probability spectrum expect ions peptide protein num_prots calc_neutral_pep_mass xpress index start_scan assumed_charge precursor_neutral_mass MZratio protein_descr pI retention_time_sec compensation_voltage precursor_intensity collision_energy inverse_reduced_ion_mobility xlink_type ppm experiment_label xcorr deltacn deltacnstar spscore sprank num_tol_term num_missed_cleavages massdiff pep_length num_saavs_min num_saavs_max peff_mods light_area heavy_area light_intensity heavy_intensity intensity_ratio fval 0.9886 230117_WJC_METTL3_WT_vs_EV_F01.02863.02863.2 0.0397 14-Jun K.TVDGPSGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 759.3763 2.81 6 2863 2 759.375773 380.6954 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.5 1267.8 - 120660 - - - -0.6716 - 0.974 0.268 - 102.9 1 2 0 -0.0005 8 0 0 0 6.62E+06 2.36E+06 - - - 0.9408 0.9741 230117_WJC_METTL3_WT_vs_EV_F01.03033.03033.2 0.359 12-Jun K.ATVEDEK.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 790.3709 3.95 12 3033 2 790.369647 396.1927 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 1298.5 - 101783 - - - -1.5385 - 0.915 0.268 - 111.3 1 2 0 -0.0012 7 0 0 0 3.39E+06 8.59E+05 - - - 0.7386 0.9261 230117_WJC_METTL3_WT_vs_EV_F01.04041.04041.2 2.43 12-May R.ITPEEAK[136.11].Y sp|P62701|RS4X_HUMAN 1 794.4265 0.84 30 4041 2 794.427057 398.2205 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.53 1478.5 - 286554 - - - 0.6583 - 1.01 0.019 - 64.7 1 2 0 0.0005 7 0 0 0 9.04E+06 1.08E+07 - - - -0.7873 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.04127.04127.2 0.0166 12-Aug K.TSQVPVK[136.11].H sp|Q9NXV2|KCTD5_HUMAN 1 765.4476 0.03 34 4127 2 765.448391 383.7311 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.41 1493.4 - 600187 - - - 1.0282 - 1.591 0.182 - 354.7 1 2 0 0.0008 7 0 0 0 5.07E+05 1.69E+07 - - - 1.8564 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.04132.04132.2 0.0183 12-Jul R.NSTIPTK.Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 759.4127 8.88 35 4132 2 759.413336 380.7136 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 1494.2 - 664054 - - - 0.8783 - 1.464 0.333 - 198.7 1 2 0 0.0007 7 0 0 0 2.67E+07 3.00E+06 - - - 2.7081 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.04157.04157.2 0.00293 18-Nov R.IAGQVAAANK.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 941.5294 1.49 38 4157 2 941.52961 471.772 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1498.4 - 622236 - - - 0.1912 - 2.1 0.305 - 320.9 1 2 0 0.0002 10 0 0 0 1.40E+07 9.35E+06 - - - 3.3646 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.04161.04161.2 0.11 12-Jul R.FTDEESR[166.11].V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 892.3802 0.74 39 4161 2 892.380063 447.1974 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1499 - 939084 - - - -0.149 - 1.282 0.293 - 161.3 1 2 0 -0.0001 7 0 0 0 2.17E+07 2.94E+07 - - - 1.9922 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.04224.04224.2 0.00443 14-Jul R.NTEEEGLK[136.11].Y "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 926.4436 1.37 42 4224 2 926.442776 464.2291 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.25 1510.1 - 429336 - - - -0.9337 - 1.491 0.391 - 268.4 1 2 0 -0.0009 8 0 0 0 3.57E+07 2.60E+07 - - - 3.1334 0.9378 230117_WJC_METTL3_WT_vs_EV_F01.04510.04510.2 0.158 16-May K.VLENAEGAR.T "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 957.488 11.53 58 4510 2 957.485104 479.7513 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.53 1559.2 - 227735 - - - -2.9818 - 1.036 0.234 - 87.4 2 2 0 -0.0029 9 0 0 0 5.66E+06 4.91E+05 - - - 0.7363 0.9486 230117_WJC_METTL3_WT_vs_EV_F01.04532.04532.2 5.24 14-May K.SVLADQGK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 816.4341 0.43 60 4532 2 816.434259 409.2243 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.55 1562.8 - 1.70E+07 - - - 0.1556 - 0.959 0.108 - 71.1 2 2 0 0.0001 8 0 0 0 3.42E+07 7.90E+07 - - - -0.4221 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.04631.04631.3 0.000285 Oct-36 R.KQDSGHLDLR.N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1167.5996 3.8 62 4631 3 1167.599438 390.2072 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1580.4 - 432813 - - - -0.1687 - 1.718 0.386 - 134.5 1 2 0 -0.0002 10 0 0 0 2.88E+07 7.56E+06 - - - 4.4239 0.9618 230117_WJC_METTL3_WT_vs_EV_F01.05171.05171.2 2.44 12-Jun K.LVEESVK[136.11].H "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 810.4578 0.45 72 5171 2 810.455183 406.2362 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 1677.5 - 609350 - - - -3.271 - 1.359 0.169 - 131.6 1 2 0 -0.0027 7 0 0 0 1.19E+07 2.62E+07 - - - 1.2604 0.9278 230117_WJC_METTL3_WT_vs_EV_F01.05422.05422.2 1.29 12-May K.MYEEHLK[136.11].R "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 956.4517 0.85 85 5422 2 956.451564 479.2331 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.38 1721 - 210451 - - - -0.1453 - 0.843 0.129 - 94.2 1 2 0 -0.0001 7 0 0 0 9.48E+06 1.12E+07 - - - -0.5474 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.05539.05539.2 2.2 12-Jul K.ITITNDK.G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 803.4389 13.36 91 5539 2 803.440247 402.7267 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1742.2 - 484275 - - - 1.6977 - 1.315 0.186 - 167.5 1 2 0 0.0014 7 0 0 0 1.39E+08 1.04E+07 - - - 1.282 0.9942 230117_WJC_METTL3_WT_vs_EV_F01.05549.05549.2 3.54 12-Apr K.ITITNDK[136.11].G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 811.4531 13.34 92 5549 2 811.454169 406.7338 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1744 - 129465 - - - 1.3383 - 1.083 0.213 - 46.4 1 2 0 0.0011 7 0 0 0 1.39E+08 1.04E+07 - - - 0.8665 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.05569.05569.2 0.0126 14-Sep K.EHC[160.03]LVGVK.G sp|Q86U44|MTA70_HUMAN 1 940.48 64.95 93 5569 2 940.483267 471.2473 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 1747.6 - 535944 - - - 3.4344 - 1.579 0.321 - 380.7 1 2 0 0.0032 8 0 0 0 8.37E+07 1.29E+06 - - - 2.7886 0.971 230117_WJC_METTL3_WT_vs_EV_F01.05801.05801.2 9.41 12-Jul K.NADELVK.Q "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 5 787.4076 9.91 98 5801 2 787.4085 394.7111 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.37 1789.5 - 795585 - - - 1.1646 - 1.122 0.048 - 178.6 1 2 0 0.0009 7 0 0 0 3.24E+07 3.27E+06 - - - -0.24 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.05803.05803.2 0.079 14-Jul K.LLEGEESR.L "sp|P08670|VIME_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P17661|DESM_HUMAN,sp|P05787|K2C8_HUMAN,sp|P41219|PERI_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 11 931.4611 1.88 99 5803 2 931.462933 466.7378 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 1789.7 - 169703 - - - 1.9947 - 1.313 0.314 - 152.5 1 2 0 0.0019 8 0 0 0 8.18E+06 4.36E+06 - - - 2.1809 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.05932.05932.2 0.396 12-May K.LAEPYGK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 776.4069 1.34 104 5932 2 776.407792 389.2107 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1812.6 - 274605 - - - 1.2068 - 1.162 0.254 - 93.9 7 2 0 0.0009 7 0 0 0 1.85E+07 1.39E+07 - - - 1.015 0.9944 230117_WJC_METTL3_WT_vs_EV_F01.06086.06086.2 0.00237 18-Aug K.GSAITGPVAK.E "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 899.5076 2.53 107 6086 2 899.50518 450.7611 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.75 1839.4 - 300931 - - - -2.7259 - 1.478 0.36 - 118.5 1 2 0 -0.0025 10 0 0 0 1.61E+07 6.36E+06 - - - 2.7897 0.9441 230117_WJC_METTL3_WT_vs_EV_F01.06136.06136.2 4.18 14-Apr R.STLEPVEK.A "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 901.4757 11.14 109 6136 2 901.476716 451.7451 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.53 1848.2 - 94154.3 - - - 1.1681 - 0.893 0.133 - 57.1 6 2 0 0.0011 8 0 0 0 6.73E+07 6.04E+06 - - - -0.6659 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.06274.06274.2 0.00286 16-Sep R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 2.14 113 6274 2 969.512914 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1873.9 - 377366 - - - 1.0675 - 1.799 0.359 - 191.1 1 2 0 0.001 9 0 0 0 8.82E+07 4.12E+07 - - - 3.3911 0.911 230117_WJC_METTL3_WT_vs_EV_F01.06498.06498.2 3.3 16-Apr K.LLADQAEAR.R "sp|P84098|RL19_HUMAN,tr|J3KTE4|J3KTE4_HUMAN,tr|A0A7I2YQG2|A0A7I2YQG2_HUMAN,tr|J3QR09|J3QR09_HUMAN" 4 985.5193 0.93 122 6498 2 985.519216 493.7669 60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1 4.37 1913.4 - 68402.7 - - - -0.0436 - 0.759 0.14 - 38 1 2 0 0 9 0 0 0 3.32E+06 3.59E+06 - - - -0.7227 0.9841 230117_WJC_METTL3_WT_vs_EV_F01.06690.06690.2 1.64 14-Jun K.VISELNGK[136.11].N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 866.4953 1.14 130 6690 2 866.496011 434.2549 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1948.2 - 221495 - - - 0.8402 - 1.111 0.113 - 107.9 1 2 0 0.0007 8 0 0 0 1.92E+07 1.67E+07 - - - 0.1928 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.06699.06699.2 0.158 14-Jul K.VISELNGK.N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 858.4811 1.14 131 6699 2 858.483122 430.2478 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1949.7 - 347057 - - - 2.3751 - 1.225 0.322 - 163.9 1 2 0 0.002 8 0 0 0 1.92E+07 1.67E+07 - - - 2.0307 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.06907.06907.2 0.00357 24-Jul K.GPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1199.6146 461.78 143 6907 2 1199.613285 600.8146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1985 - 96754.9 - - - -1.1095 - 1.563 0.334 - 65.9 1 2 0 -0.0013 13 0 0 0 8.25E+06 1.79E+04 - - - 2.6537 0.9922 230117_WJC_METTL3_WT_vs_EV_F01.06976.06976.2 1.51 14-Jul R.GTLDPVEK.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 857.4494 13.38 145 6976 2 857.450466 429.732 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.37 1997.7 - 309184 - - - 1.1872 - 1.279 0.118 - 166 1 2 0 0.001 8 0 0 0 1.05E+08 7.82E+06 - - - 0.6544 0.9709 230117_WJC_METTL3_WT_vs_EV_F01.06985.06985.2 0.0265 12-Aug R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 702.32 146 6985 2 776.377639 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1999.1 - 2.37E+06 - - - -5.2345 - 1.619 0.286 - 259.5 1 2 0 -0.0041 7 0 0 0 5.79E+09 8.24E+06 - - - 2.6788 0.991 230117_WJC_METTL3_WT_vs_EV_F01.07121.07121.2 0.0645 16-Aug K.SAAMTLNER[166.11].F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1001.484 0.79 153 7121 2 1001.480912 501.7493 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 2022.7 - 1.32E+06 - - - -3.0335 - 1.62 0.276 - 110.7 1 2 0 -0.003 9 0 0 0 1.96E+07 2.47E+07 - - - 2.4743 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.07171.07171.2 0.217 12-Jun R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 1.19 155 7171 2 776.382672 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2031.5 - 622762 - - - 1.2481 - 1.337 0.272 - 115.4 1 2 0 0.001 7 0 0 0 1.02E+08 8.55E+07 - - - 1.9699 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.07206.07206.2 0.00206 14-Jul K.GANPVEIR.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 854.461 1.81 158 7206 2 854.460833 428.2378 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 2037.6 - 296250 - - - -0.2142 - 1.275 0.286 - 183.3 1 2 0 -0.0002 8 0 0 0 6.59E+07 3.64E+07 - - - 1.8861 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.07240.07240.2 0.295 14-Jun R.ELTAVVQK[136.11].R "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 894.5266 2.14 160 7240 2 894.526665 448.2706 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.1 2043.5 - 99066.7 - - - 0.0917 - 1.14 0.256 - 153.3 1 2 0 0.0001 8 0 0 0 1.26E+07 5.88E+06 - - - 1.327 0.996 230117_WJC_METTL3_WT_vs_EV_F01.07261.07261.2 0.373 12-Aug R.IGVITNR.E sp|P62701|RS4X_HUMAN 1 771.4603 0.89 163 7261 2 771.461026 386.7374 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2047 - 448122 - - - 0.9579 - 1.557 0.098 - 234.9 1 2 0 0.0007 7 0 0 0 2.12E+07 2.38E+07 - - - 1.1675 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.07285.07285.2 0.0153 14-Sep K.VGEVIVTK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.5208 2.03 167 7285 2 851.522848 426.7677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2051 - 479919 - - - 2.4415 - 2.035 0.266 - 231.3 1 2 0 0.0021 8 0 0 0 1.24E+08 6.08E+07 - - - 3.1478 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.07300.07300.2 0.00541 14-Oct K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 2.03 168 7300 2 843.508911 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2053.8 - 1.87E+06 - - - 2.7765 - 2.261 0.356 - 303.5 1 2 0 0.0023 8 0 0 0 1.24E+08 6.08E+07 - - - 4.1301 0.9947 230117_WJC_METTL3_WT_vs_EV_F01.07419.07419.2 0.0759 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 140.7 179 7419 2 776.382466 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2074.4 - 251613 - - - 0.9828 - 1.347 0.13 - 197.6 1 2 0 0.0008 7 0 0 0 3.25E+07 2.31E+05 - - - 0.9448 0.9915 230117_WJC_METTL3_WT_vs_EV_F01.07614.07614.3 0.0359 Jul-44 R.TLVAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1299.763 0.68 189 7614 3 1299.763394 434.2616 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2108.1 - 95043.4 - - - 0.3378 - 1.323 0.215 - 45.9 1 2 0 0.0004 12 0 0 0 5.57E+06 8.18E+06 - - - 1.7128 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.07640.07640.2 0.0489 16-Aug K.VTMQNLNDR.L "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 8 1089.5237 999 192 7640 2 1089.523741 545.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.81 2112.6 - 190730 - - - 0.045 - 1.565 0.31 - 224.4 1 2 0 0 9 0 0 0 7.64E+06 0.00E+00 - - - 2.6264 0.9914 230117_WJC_METTL3_WT_vs_EV_F01.07726.07726.2 0.245 16-Jul R.VLNTNIDGR[166.11].R "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1010.5384 1.65 202 7726 2 1010.542759 506.2765 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.81 2126.9 - 94483.5 - - - 4.2858 - 1.311 0.256 - 145.9 1 2 0 0.0043 9 0 0 0 3.15E+07 1.91E+07 - - - 1.7139 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.07736.07736.2 0.00292 16-Jul R.VLNTNIDGR.R "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1000.5302 1.65 204 7736 2 1000.530423 501.2724 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.81 2128.5 - 248892 - - - 0.2649 - 1.639 0.321 - 150.1 1 2 0 0.0003 9 0 0 0 3.16E+07 1.91E+07 - - - 2.8412 0.998 230117_WJC_METTL3_WT_vs_EV_F01.07761.07761.2 0.137 14-Jul R.VLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 815.4753 0.93 207 7761 2 815.474802 408.7449 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 2132.6 - 576951 - - - -0.5727 - 1.403 0.316 - 207.4 1 2 0 -0.0005 8 0 0 0 3.63E+07 3.91E+07 - - - 2.3961 0.9628 230117_WJC_METTL3_WT_vs_EV_F01.07780.07780.2 3.57 14-Jun R.LASEGSAR.L "sp|Q9HBI6|CP4FB_HUMAN,sp|Q08477|CP4F3_HUMAN,tr|F8W978|F8W978_HUMAN" 3 789.3981 1.78 210 7780 2 789.402003 395.7063 Cytochrome P450 4F11 OS=Homo sapiens OX=9606 GN=CYP4F11 PE=1 SV=3 6 2135.6 - 195716 - - - 4.9683 - 1.233 0.165 - 141.7 1 2 0 0.0039 8 0 0 0 1.61E+07 9.08E+06 - - - 0.8902 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.07816.07816.2 0.00969 16-Jul K.DVDGAYMTK.V sp|P04264|K2C1_HUMAN 1 998.4379 137.13 221 7816 2 998.439934 500.2262 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.21 2140.8 - 186417 - - - 2.0402 - 1.3 0.431 - 115.1 1 2 0 0.002 9 0 0 0 6.78E+06 4.94E+04 - - - 2.9828 0.9269 230117_WJC_METTL3_WT_vs_EV_F01.07848.07848.2 0.488 14-Jul R.FSELTAEK.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 923.46 6.84 226 7848 2 923.466404 462.7373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2146.1 - 1.37E+06 - - - 6.9207 - 1.113 0.267 - 90.2 1 2 0 0.0064 8 0 0 0 4.25E+07 6.21E+06 - - - 1.3339 0.9564 230117_WJC_METTL3_WT_vs_EV_F01.07857.07857.2 20.2 12-Jun R.IPPVAVR[166.11].L "sp|Q14839|CHD4_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A0G2JM70|A0A0G2JM70_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|V9GYG6|V9GYG6_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 760.4835 0.001 227 7857 2 760.483539 381.249 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 2147.6 - 863342 - - - 0.0789 - 1.082 0.075 - 135.2 2 2 0 0.0001 7 0 0 0 0.00E+00 1.68E+08 - - - -0.2898 0.9695 230117_WJC_METTL3_WT_vs_EV_F01.07913.07913.2 0.000546 16-Sep Y.PDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 953.5546 999 229 7913 2 953.554677 477.7846 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2157.4 - 335524 - - - 0.0996 - 1.918 0.451 - 269.3 1 1 0 0.0001 9 0 0 0 3.39E+07 0.00E+00 - - - 4.2563 0.8586 230117_WJC_METTL3_WT_vs_EV_F01.07930.07930.2 0.0584 12-Jun D.VIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 784.4807 8.63 231 7930 2 784.480993 393.2476 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 2160.2 - 1.63E+06 - - - 0.3875 - 1.317 0.265 - 190 1 1 0 0.0003 7 0 0 0 7.80E+07 9.04E+06 - - - 1.8707 1 230117_WJC_METTL3_WT_vs_EV_F01.07941.07941.2 1.01E-05 15/18 R.YPDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 1116.6179 321.92 234 7941 2 1116.619152 559.3162 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2161.9 - 1.34E+06 - - - 1.1123 - 2.21 0.546 - 680.8 1 2 0 0.0012 10 0 0 0 8.31E+07 2.58E+05 - - - 5.2868 0.8669 230117_WJC_METTL3_WT_vs_EV_F01.08027.08027.2 0.093 12-May M.VSMVMDR.E "sp|Q9UJ98|STAG3_HUMAN,tr|D6W5U7|D6W5U7_HUMAN" 2 836.3884 2.37 248 8027 2 836.388715 419.2015 Cohesin subunit SA-3 OS=Homo sapiens OX=9606 GN=STAG3 PE=1 SV=2 5.81 2175.8 - 499266 - - - 0.324 - 1.203 0.316 - 128.2 1 1 0 0.0003 7 0 0 0 9.16E+07 3.87E+07 - - - 1.9605 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.08031.08031.2 0.0374 16-Oct R.TLLEGEESR.M sp|P04264|K2C1_HUMAN 1 1032.5088 53.11 249 8031 2 1032.509328 517.2617 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.25 2176.4 - 618703 - - - 0.5559 - 1.764 0.45 - 366.9 1 2 0 0.0006 9 0 0 0 4.52E+07 8.51E+05 - - - 4.0066 0.9792 230117_WJC_METTL3_WT_vs_EV_F01.08178.08178.2 3.45 14-Jul K.VC[160.03]NPIITK.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 943.5161 15.66 262 8178 2 943.51596 472.7653 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.19 2201.2 - 299900 - - - -0.1357 - 1.207 0.091 - 114 1 2 0 -0.0001 8 0 0 0 1.03E+08 6.57E+06 - - - 0.2805 0.9823 230117_WJC_METTL3_WT_vs_EV_F01.08183.08183.2 2.19 16-Jun R.VPPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 942.5651 1.12 264 8183 2 942.567597 472.2898 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2201.8 - 409545 - - - 2.6629 - 1.128 0.16 - 120.8 3 2 0 0.0025 9 0 0 0 3.65E+07 3.27E+07 - - - 0.3573 0.991 230117_WJC_METTL3_WT_vs_EV_F01.08215.08215.2 0.0458 12-Jun R.FC[160.03]ALEEK.C "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 895.411 0.32 267 8215 2 895.410646 448.7128 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2207.2 - 131065 - - - -0.344 - 1.074 0.231 - 118 1 2 0 -0.0003 7 0 0 0 9.90E+06 3.13E+07 - - - 0.9733 0.9899 230117_WJC_METTL3_WT_vs_EV_F01.08218.08218.2 0.267 16-Jun R.VPPPPPIAR[166.11].A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 952.5734 1.05 268 8218 2 952.573843 477.294 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2207.6 - 271596 - - - 0.5102 - 1.088 0.193 - 112.5 2 2 0 0.0005 9 0 0 0 3.77E+07 3.58E+07 - - - 0.5759 0.9956 230117_WJC_METTL3_WT_vs_EV_F01.08271.08271.2 0.117 12-Jul K.VLAAVYK[136.11].A "sp|P05062|ALDOB_HUMAN,sp|P04075|ALDOA_HUMAN,sp|P09972|ALDOC_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|A8MVZ9|A8MVZ9_HUMAN,tr|A0A3B3IS80|A0A3B3IS80_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|A0A087WXX2|A0A087WXX2_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 10 770.4782 1.93 274 8271 2 770.479373 386.2464 Fructose-bisphosphate aldolase B OS=Homo sapiens OX=9606 GN=ALDOB PE=1 SV=2 8.56 2216.8 - 624098 - - - 1.5536 - 1.46 0.114 - 181.9 1 2 0 0.0012 7 0 0 0 2.13E+08 1.10E+08 - - - 1.0817 0.9744 230117_WJC_METTL3_WT_vs_EV_F01.08318.08318.2 4.28 12-Jun K.LVTDLTK.V "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 788.4644 2.6 279 8318 2 788.465755 395.2395 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.84 2224.8 - 782134 - - - 1.7566 - 1.141 0.055 - 101.3 1 2 0 0.0014 7 0 0 0 3.00E+07 1.15E+07 - - - -0.1353 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.08322.08322.2 0.00164 18-Nov K.LLNTVEETTK[136.11].D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1154.6274 0.07 280 8322 2 1154.629517 578.321 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2225.4 - 581110 - - - 1.817 - 2.256 0.378 - 342.7 1 2 0 0.0021 10 0 0 0 1.72E+06 2.57E+07 - - - 4.1032 0.9927 230117_WJC_METTL3_WT_vs_EV_F01.08327.08327.2 0.228 12-Jul R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 404.85 282 8327 2 808.433342 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2226 - 1.42E+06 - - - 0.3365 - 1.274 0.142 - 102.3 1 2 0 0.0003 7 0 0 0 1.47E+08 3.63E+05 - - - 0.857 0.9911 230117_WJC_METTL3_WT_vs_EV_F01.08337.08337.2 0.0779 14-Jun R.ILSGVVTK.M "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 815.5117 0.87 284 8337 2 815.511779 408.7631 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 2227.5 - 688035 - - - 0.1533 - 1.44 0.104 - 92.6 2 2 0 0.0001 8 0 0 0 3.91E+07 4.50E+07 - - - 0.7744 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.08429.08429.2 0.000206 18-Aug R.ASAVSELSPR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1025.5381 0.89 301 8429 2 1025.538034 513.7763 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2242.4 - 132285 - - - -0.0585 - 1.692 0.19 - 176.8 1 2 0 -0.0001 10 0 0 0 1.29E+07 1.45E+07 - - - 1.9123 0.9458 230117_WJC_METTL3_WT_vs_EV_F01.08526.08526.3 0.108 Jul-44 K.LSAMMGAVAEKK.G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1234.6414 999 309 8526 3 1234.641325 412.5544 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2258.8 - 270320 - - - -0.0324 - 1.236 0.16 - 27.9 4 2 0 0 12 0 0 0 7.05E+06 0.00E+00 - - - 0.6325 1 230117_WJC_METTL3_WT_vs_EV_F01.08535.08535.2 2.13E-05 20-Dec K.FAEALGSTEAK[136.11].A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1130.5699 0.4 311 8535 2 1130.569966 566.2922 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2260.1 - 361043 - - - 0.0548 - 2.269 0.521 - 404 1 2 0 0.0001 11 0 0 0 6.14E+06 1.54E+07 - - - 5.1056 0.9872 230117_WJC_METTL3_WT_vs_EV_F01.08549.08549.2 7.37 12-Jun K.SEITELR.R "sp|P13645|K1C10_HUMAN,sp|Q8TDM6|DLG5_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 3 846.4447 4.45 315 8549 2 846.444926 424.2296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2262.1 - 296887 - - - 0.2705 - 1.18 0.123 - 206.6 1 2 0 0.0002 7 0 0 0 1.26E+07 2.82E+06 - - - 0.4738 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.08651.08651.2 0.0178 16-Sep R.ILQDSLGGR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 967.5326 0.33 331 8651 2 967.533381 484.7736 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2278.4 - 246968 - - - 0.7927 - 1.655 0.253 - 251.9 1 2 0 0.0008 9 0 0 0 6.98E+06 2.11E+07 - - - 2.3669 0.9771 230117_WJC_METTL3_WT_vs_EV_F01.08659.08659.2 0.0747 14-Jul K.VGVNGFGR[166.11].L sp|P04406|G3P_HUMAN 1 814.4325 0.78 334 8659 2 814.431557 408.2235 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 2279.4 - 257396 - - - -1.1652 - 1.324 0.104 - 126.3 1 2 0 -0.0009 8 0 0 0 1.93E+07 2.47E+07 - - - 0.6553 0.9736 230117_WJC_METTL3_WT_vs_EV_F01.08684.08684.2 4.43 16-Jul R.ILQDSLGGR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 957.5243 0.33 339 8684 2 957.525707 479.7694 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2283.4 - 141600 - - - 1.4235 - 1.2 0.034 - 113.7 1 2 0 0.0014 9 0 0 0 6.98E+06 2.11E+07 - - - -0.1808 0.9866 230117_WJC_METTL3_WT_vs_EV_F01.08755.08755.2 0.163 16-May R.TLSDYNIQK.E "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 21 1080.5451 1.53 348 8755 2 1080.547892 541.2798 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 5.5 2295.1 - 420645 - - - 2.5478 - 1.132 0.223 - 32.7 16 2 0 0.0028 9 0 0 0 9.12E+06 5.97E+06 - - - 0.508 0.9006 230117_WJC_METTL3_WT_vs_EV_F01.08775.08775.2 6.36 12-Jun R.LLEQGIR.V "sp|P28340|DPOD1_HUMAN,sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 7 827.4865 1.79 350 8775 2 827.485988 414.7505 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 6 2298.5 - 420219 - - - -0.6212 - 1.107 0.007 - 114 1 2 0 -0.0005 7 0 0 0 4.49E+07 2.51E+07 - - - -0.5854 0.9911 230117_WJC_METTL3_WT_vs_EV_F01.08819.08819.2 0.0653 12-Aug K.NIQVVVR[166.11].C "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 836.5108 0.31 357 8819 2 836.508693 419.2627 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 9.75 2305.4 - 1.16E+06 - - - -2.4674 - 1.425 0.265 - 281 1 2 0 -0.0021 7 0 0 0 2.68E+07 8.62E+07 - - - 2.1199 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.08901.08901.2 0.0665 12-Aug R.AMIIAER[166.11].Q "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 812.4454 1.9 363 8901 2 812.443702 407.23 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.05 2318.9 - 893250 - - - -2.0641 - 1.545 0.258 - 319.2 1 2 0 -0.0017 7 0 0 0 8.06E+07 4.25E+07 - - - 2.3245 0.9949 230117_WJC_METTL3_WT_vs_EV_F01.08913.08913.2 0.555 12-Oct R.HLQLAIR[166.11].N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 859.5267 0.81 366 8913 2 859.525486 430.7706 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2320.7 - 988689 - - - -1.4601 - 1.606 0.204 - 407.9 1 2 0 -0.0013 7 0 0 0 9.72E+07 1.20E+08 - - - 2.0484 0.9599 230117_WJC_METTL3_WT_vs_EV_F01.08921.08921.2 0.141 12-Jul R.AMIIAER.Q "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 802.4371 1.86 369 8921 2 802.43534 402.2258 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.05 2321.7 - 1.36E+06 - - - -2.2045 - 1.558 0.037 - 232.2 1 2 0 -0.0018 7 0 0 0 7.89E+07 4.25E+07 - - - 0.7187 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.08939.08939.2 0.0305 16-Jul R.NIVEAAAVR.D "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 941.5294 1.05 373 8939 2 941.52803 471.772 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 6 2324.4 - 380845 - - - -1.4869 - 1.561 0.343 - 143.3 1 2 0 -0.0014 9 0 0 0 2.38E+07 2.26E+07 - - - 2.8623 0.9867 230117_WJC_METTL3_WT_vs_EV_F01.08942.08942.2 0.198 12-Aug R.LYAVVTR.E sp|P07948|LYN_HUMAN 1 820.4807 6.3 374 8942 2 820.479879 411.2476 Tyrosine-protein kinase Lyn OS=Homo sapiens OX=9606 GN=LYN PE=1 SV=3 8.75 2324.7 - 347090 - - - -0.9872 - 1.542 0.076 - 218.8 1 2 0 -0.0008 7 0 0 0 2.31E+07 3.68E+06 - - - 0.9743 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.08960.08960.2 0.134 16-Aug R.NIVEAAAVR[166.11].D "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 951.5377 1.05 377 8960 2 951.538491 476.7761 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 6 2327.6 - 628015 - - - 0.8313 - 1.141 0.274 - 215.8 1 2 0 0.0008 9 0 0 0 2.38E+07 2.26E+07 - - - 1.4461 0.9868 230117_WJC_METTL3_WT_vs_EV_F01.08978.08978.2 2.48 12-Jun K.LIETVVK[136.11].Q "sp|Q8TAG9|EXOC6_HUMAN,tr|E7EW84|E7EW84_HUMAN" 2 808.515 1.65 378 8978 2 808.516442 405.2648 Exocyst complex component 6 OS=Homo sapiens OX=9606 GN=EXOC6 PE=1 SV=3 6 2330.7 - 261627 - - - 1.8392 - 1.179 0.103 - 84.9 1 2 0 0.0015 7 0 0 0 1.85E+07 1.13E+07 - - - 0.323 0.9939 230117_WJC_METTL3_WT_vs_EV_F01.08982.08982.2 0.172 14-Jun K.LVIEEAER.S sp|P50991|TCPD_HUMAN 1 957.5131 14.22 379 8982 2 957.512847 479.7638 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.25 2331.3 - 276366 - - - -0.2757 - 1.294 0.192 - 102.5 1 2 0 -0.0003 8 0 0 0 1.13E+07 7.98E+05 - - - 1.2364 0.9895 230117_WJC_METTL3_WT_vs_EV_F01.09007.09007.2 3.06 12-Aug K.IIDAALR.A "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 770.465 2.24 381 9007 2 770.464371 386.2398 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2335.6 - 2.58E+06 - - - -0.8657 - 1.358 0.147 - 203.4 1 2 0 -0.0007 7 0 0 0 2.87E+09 1.28E+09 - - - 1.0962 0.8805 230117_WJC_METTL3_WT_vs_EV_F01.09013.09013.2 4.45 14-May R.GLFIIDGK.G sp|P32119|PRDX2_HUMAN 1 861.496 3.56 382 9013 2 861.498809 431.7553 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 2336.5 - 185065 - - - 3.256 - 0.889 0.082 - 71.3 1 2 0 0.0028 8 0 0 0 6.19E+06 1.74E+06 - - - -0.7091 0.9948 230117_WJC_METTL3_WT_vs_EV_F01.09091.09091.2 0.809 12-Jun R.VLVDVER[166.11].G sp|P08621|RU17_HUMAN 1 838.4788 1.78 392 9091 2 838.478389 420.2467 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 4.37 2349.1 - 337278 - - - -0.4759 - 1.454 0.168 - 150.3 1 2 0 -0.0004 7 0 0 0 4.16E+07 2.34E+07 - - - 1.4678 0.9338 230117_WJC_METTL3_WT_vs_EV_F01.09159.09159.2 3.39 14-May R.IGVLDEGK.M "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 829.4545 0.51 400 9159 2 829.45408 415.7345 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 4.37 2360 - 132555 - - - -0.5461 - 1.104 0.08 - 47.2 4 2 0 -0.0005 8 0 0 0 5.89E+06 1.16E+07 - - - -0.3388 0.9793 230117_WJC_METTL3_WT_vs_EV_F01.09184.09184.2 0.301 14-Jun K.FVIATSTK[136.11].L sp|Q02878|RL6_HUMAN 1 873.5051 1.87 404 9184 2 873.507046 437.7598 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 8.75 2364 - 127965 - - - 2.2061 - 0.983 0.15 - 77.9 1 2 0 0.0019 8 0 0 0 6.30E+06 3.37E+06 - - - 0.0966 0.9929 230117_WJC_METTL3_WT_vs_EV_F01.09189.09189.2 0.617 12-Aug R.LVGEIVR.R "sp|Q13232|NDK3_HUMAN,sp|Q15021|CND1_HUMAN,sp|Q3MIP1|IPIL2_HUMAN,tr|H3BRA8|H3BRA8_HUMAN,tr|H3BMQ7|H3BMQ7_HUMAN,tr|H3BPD9|H3BPD9_HUMAN,tr|E7EN77|E7EN77_HUMAN" 7 784.4807 1.07 406 9189 2 784.481896 393.2476 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6 2364.6 - 3.19E+06 - - - 1.5386 - 1.329 0.106 - 236.4 1 2 0 0.0012 7 0 0 0 4.43E+08 4.13E+08 - - - 0.7248 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.09199.09199.2 0.953 12-Jun R.LVGEIVR[166.11].R "sp|Q13232|NDK3_HUMAN,sp|Q15021|CND1_HUMAN,sp|Q3MIP1|IPIL2_HUMAN,tr|H3BRA8|H3BRA8_HUMAN,tr|H3BMQ7|H3BMQ7_HUMAN,tr|H3BPD9|H3BPD9_HUMAN,tr|E7EN77|E7EN77_HUMAN" 7 794.489 1.32 409 9199 2 794.490382 398.2518 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6 2366.1 - 5.51E+06 - - - 1.7911 - 1.38 0.178 - 120.3 2 2 0 0.0014 7 0 0 0 5.55E+08 4.20E+08 - - - 1.2413 0.8728 230117_WJC_METTL3_WT_vs_EV_F01.09208.09208.2 0.158 14-Oct F.LLAQTTLR[166.11].N "sp|Q8TAV4|STML3_HUMAN,sp|P27105|STOM_HUMAN,tr|F8VSL7|F8VSL7_HUMAN" 3 924.5632 7.06 410 9208 2 924.564529 463.2889 Stomatin-like protein 3 OS=Homo sapiens OX=9606 GN=STOML3 PE=1 SV=1 9.75 2367.6 - 285942 - - - 1.4526 - 1.442 0.224 - 309.4 1 1 0 0.0013 8 0 0 0 1.07E+08 1.51E+07 - - - 1.799 0.9839 230117_WJC_METTL3_WT_vs_EV_F01.09246.09246.2 0.363 14-Jun R.INVELSTK.G sp|Q96PK6|RBM14_HUMAN 1 902.5073 0.5 421 9246 2 902.507049 452.2609 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6 2373.5 - 153401 - - - -0.2748 - 1.17 0.154 - 71.9 2 2 0 -0.0002 8 0 0 0 5.42E+06 1.09E+07 - - - 0.5174 0.9937 230117_WJC_METTL3_WT_vs_EV_F01.09269.09269.2 0.992 12-Jun R.DLAENIR.K tr|A0A0C4DGZ7|A0A0C4DGZ7_HUMAN 1 829.4294 2.66 425 9269 2 829.429833 415.722 Ankyrin repeat and death domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ANKDD1A PE=4 SV=1 4.37 2377.3 - 345699 - - - 0.545 - 1.123 0.203 - 131.3 1 2 0 0.0005 7 0 0 0 3.49E+07 1.31E+07 - - - 0.9078 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.09286.09286.2 0.0132 12-Aug R.FANYIDK.V "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 869.4283 1.63 427 9286 2 869.428652 435.7214 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.83 2380 - 1.34E+06 - - - 0.383 - 1.653 0.354 - 187.4 1 2 0 0.0003 7 0 0 0 5.11E+07 3.14E+07 - - - 3.248 0.9513 230117_WJC_METTL3_WT_vs_EV_F01.09304.09304.2 0.00252 14-Sep R.PVGVVVPR[166.11].G "sp|O75525|KHDR3_HUMAN,tr|H0YAQ3|H0YAQ3_HUMAN,tr|E5RJZ9|E5RJZ9_HUMAN,tr|H0YAQ1|H0YAQ1_HUMAN" 4 831.5206 1.13 430 9304 2 831.520856 416.7676 "KH domain-containing, RNA-binding, signal transduction-associated protein 3 OS=Homo sapiens OX=9606 GN=KHDRBS3 PE=1 SV=1" 10.18 2382.9 - 598613 - - - 0.3163 - 1.629 0.363 - 277.6 1 1 0 0.0003 8 0 0 0 3.68E+07 3.26E+07 - - - 3.1937 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.09312.09312.2 0.167 14-Jul K.QLIVGVNK.M "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,sp|P06276|CHLE_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|F8WF14|F8WF14_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|F8WEX7|F8WEX7_HUMAN" 13 869.5335 4.13 432 9312 2 869.5333 435.774 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2384 - 952666 - - - -0.1748 - 1.369 0.197 - 132.4 1 2 0 -0.0002 8 0 0 0 6.58E+07 1.59E+07 - - - 1.4432 0.9853 230117_WJC_METTL3_WT_vs_EV_F01.09317.09317.2 1.08 14-Jun K.QLIVGVNK[136.11].M "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,sp|P06276|CHLE_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|F8WF14|F8WF14_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|F8WEX7|F8WEX7_HUMAN" 13 877.5477 4.13 434 9317 2 877.547561 439.7811 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2384.6 - 278779 - - - -0.1037 - 1.208 0.151 - 81.9 3 2 0 -0.0001 8 0 0 0 6.58E+07 1.59E+07 - - - 0.513 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.09319.09319.2 0.0209 16-Aug R.QTVAVGVIK.N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 913.5597 4.46 435 9319 2 913.559542 457.7871 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2384.8 - 1.02E+06 - - - -0.1368 - 1.613 0.363 - 292.7 1 2 0 -0.0001 9 0 0 0 8.50E+07 1.90E+07 - - - 3.1052 0.9941 230117_WJC_METTL3_WT_vs_EV_F01.09373.09373.2 0.109 14-Jul R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 1.22 445 9373 2 898.526537 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 2393.4 - 455532 - - - 3.2509 - 1.207 0.249 - 142.7 1 2 0 0.0029 8 0 0 0 6.86E+07 5.62E+07 - - - 1.4466 0.933 230117_WJC_METTL3_WT_vs_EV_F01.09375.09375.2 4.04 12-May K.IITPLNK[136.11].D "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 805.5153 2.58 447 9375 2 805.516557 403.7649 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 8.75 2393.7 - 407065 - - - 1.5729 - 0.931 0.055 - 52.5 1 2 0 0.0013 7 0 0 0 8.79E+06 3.41E+06 - - - -0.7797 0.9872 230117_WJC_METTL3_WT_vs_EV_F01.09409.09409.2 0.904 12-May K.VVPLYGR.G "sp|Q99942|RNF5_HUMAN,tr|A0A140TA09|A0A140TA09_HUMAN" 2 802.4701 2.1 454 9409 2 802.471651 402.2423 E3 ubiquitin-protein ligase RNF5 OS=Homo sapiens OX=9606 GN=RNF5 PE=1 SV=1 8.72 2398.9 - 1.28E+06 - - - 1.9029 - 1.027 0.166 - 147.9 1 2 0 0.0015 7 0 0 0 8.46E+07 4.04E+07 - - - 0.351 0.997 230117_WJC_METTL3_WT_vs_EV_F01.09413.09413.2 0.0225 12-Jun K.VVPLYGR[166.11].G "sp|Q99942|RNF5_HUMAN,tr|A0A140TA09|A0A140TA09_HUMAN" 2 812.4784 2 456 9413 2 812.479261 407.2465 E3 ubiquitin-protein ligase RNF5 OS=Homo sapiens OX=9606 GN=RNF5 PE=1 SV=1 8.72 2399.4 - 848795 - - - 1.0671 - 1.279 0.211 - 218.2 1 2 0 0.0009 7 0 0 0 8.00E+07 3.99E+07 - - - 1.3789 0.9876 230117_WJC_METTL3_WT_vs_EV_F01.09465.09465.2 0.368 16-May K.TIAPALVSK[136.11].K "sp|P06733|ENOA_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y6I8|A0A2R8Y6I8_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 6 906.563 1.25 464 9465 2 906.564576 454.2888 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 8.41 2408 - 111841 - - - 1.7737 - 1.226 0.149 - 82 7 2 0 0.0016 9 0 0 0 9.76E+06 7.78E+06 - - - 0.353 0.9454 230117_WJC_METTL3_WT_vs_EV_F01.09473.09473.2 0.00329 14-Aug R.YPDGIISK.P sp|Q86U44|MTA70_HUMAN 1 891.4702 217.93 465 9473 2 891.472372 446.7424 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2409.4 - 1.44E+06 - - - 2.4555 - 1.555 0.372 - 182.4 1 1 0 0.0022 8 0 0 0 4.53E+08 2.08E+06 - - - 3.1194 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.09477.09477.2 0.277 16-Aug K.TIAPALVSK.K "sp|P06733|ENOA_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y6I8|A0A2R8Y6I8_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 6 898.5488 1.24 466 9477 2 898.551092 450.2817 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 8.41 2410 - 198060 - - - 2.5864 - 1.243 0.296 - 177.5 1 2 0 0.0023 9 0 0 0 1.02E+07 8.21E+06 - - - 1.8558 0.8579 230117_WJC_METTL3_WT_vs_EV_F01.09490.09490.2 6.61 12-Jul R.IAPDVLR[166.11].K "sp|Q13367|AP3B2_HUMAN,sp|O00203|AP3B1_HUMAN,tr|A0A590UK64|A0A590UK64_HUMAN,tr|A0A590UK04|A0A590UK04_HUMAN,tr|A0A5F9UJV3|A0A5F9UJV3_HUMAN,tr|A0A590UJU0|A0A590UJU0_HUMAN,tr|A0A590UKD3|A0A590UKD3_HUMAN,tr|A0A590UJE5|A0A590UJE5_HUMAN,tr|A0A590UJU7|A0A590UJU7_HUMAN,tr|A0A2R8Y2A8|A0A2R8Y2A8_HUMAN,tr|A0A590UJ60|A0A590UJ60_HUMAN,tr|A0A590UKC4|A0A590UKC4_HUMAN" 12 792.4733 1.68 470 9490 2 792.478064 397.2439 AP-3 complex subunit beta-2 OS=Homo sapiens OX=9606 GN=AP3B2 PE=1 SV=2 5.84 2411.8 - 1.47E+06 - - - 6.0015 - 1.195 0.102 - 135.5 1 2 0 0.0048 7 0 0 0 3.53E+07 2.10E+07 - - - 0.3573 0.981 230117_WJC_METTL3_WT_vs_EV_F01.09513.09513.2 0.186 12-May R.IVTTYIR.E "sp|P50570|DYN2_HUMAN,tr|K7EMQ3|K7EMQ3_HUMAN" 2 864.5069 1.46 475 9513 2 864.507357 433.2607 Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2 8.75 2415.4 - 272700 - - - 0.5252 - 1.072 0.118 - 76 1 2 0 0.0005 7 0 0 0 2.97E+07 2.03E+07 - - - 0.1327 0.9451 230117_WJC_METTL3_WT_vs_EV_F01.09564.09564.2 3.13 12-May R.IILPPEK[136.11].E sp|P49411|EFTU_HUMAN 1 816.52 3.97 483 9564 2 816.521308 409.2673 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6 2423.5 - 255639 - - - 1.5517 - 0.965 0.057 - 81.7 1 2 0 0.0013 7 0 0 0 1.18E+08 2.98E+07 - - - -0.6513 0.9289 230117_WJC_METTL3_WT_vs_EV_F01.09596.09596.2 5.9 12-Jul R.LGLVDTR.Q sp|Q6P4I2|WDR73_HUMAN 1 772.4443 9.09 490 9596 2 772.44725 387.2294 WD repeat-containing protein 73 OS=Homo sapiens OX=9606 GN=WDR73 PE=1 SV=1 5.84 2428.5 - 2.23E+06 - - - 3.8152 - 1.241 0.021 - 112.8 1 2 0 0.0029 7 0 0 0 1.62E+07 1.78E+06 - - - -0.1207 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.09598.09598.2 0.0155 18-Jul R.GYSFTTTAER[166.11].E "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1141.5279 1.34 491 9598 2 1141.528918 571.7712 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 2428.7 - 98507.3 - - - 0.8716 - 1.141 0.258 - 102.9 1 2 0 0.001 10 0 0 0 6.69E+06 5.01E+06 - - - 1.3145 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.09607.09607.2 0.00805 18-Sep K.FADLSEAANR.N "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1092.52 1.51 495 9607 2 1092.520707 547.2673 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 2429.9 - 266756 - - - 0.659 - 1.789 0.365 - 271.1 1 2 0 0.0007 10 0 0 0 2.86E+07 1.89E+07 - - - 3.3602 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.09610.09610.2 0.000175 18-Jul R.GYSFTTTAER.E "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1131.5197 1.34 496 9610 2 1131.520302 566.7671 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 2430.3 - 130171 - - - 0.5736 - 1.556 0.462 - 170.4 1 2 0 0.0006 10 0 0 0 6.69E+06 5.01E+06 - - - 3.6872 0.999 230117_WJC_METTL3_WT_vs_EV_F01.09633.09633.2 0.00133 16-Aug R.QAVDVSPLR[166.11].R "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 993.5483 1.09 500 9633 2 993.550665 497.7814 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 5.84 2434 - 115732 - - - 2.4166 - 1.432 0.354 - 151.8 1 2 0 0.0024 9 0 0 0 4.94E+06 4.54E+06 - - - 2.6937 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.09663.09663.2 4.76 14-Aug R.LLTGPVVR.G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 853.5385 2.53 506 9663 2 853.539738 427.7765 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2438.7 - 496990 - - - 1.4059 - 1.523 0.256 - 178.5 1 2 0 0.0012 8 0 0 0 4.69E+07 1.86E+07 - - - 2.2002 0.8737 230117_WJC_METTL3_WT_vs_EV_F01.09682.09682.2 0.000981 22-Jun F.SGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1155.5408 999 512 9682 2 1155.540794 578.7777 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.55 2441.3 - 121662 - - - 0.0104 - 1.31 0.327 - 116.3 1 1 0 0 12 0 0 0 5.31E+06 0.00E+00 - - - 2.1667 0.9663 230117_WJC_METTL3_WT_vs_EV_F01.09712.09712.2 3.8 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 197.86 516 9712 2 841.502235 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 2446.2 - 4.86E+06 - - - 0.0986 - 1.309 0.021 - 198.8 2 2 0 0.0001 8 0 0 0 8.36E+08 4.23E+06 - - - -0.1263 0.999 230117_WJC_METTL3_WT_vs_EV_F01.09713.09713.2 0.0417 14-Aug K.ALVAYYQK[136.11].Y "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 962.5317 3.28 517 9713 2 962.534551 482.2731 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.54 2446.4 - 175670 - - - 2.9952 - 1.677 0.341 - 241.9 1 2 0 0.0029 8 0 0 0 2.77E+07 8.45E+06 - - - 3.118 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.09760.09760.3 0.000285 15/40 R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 0.79 527 9760 3 1240.609316 414.5431 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2453.7 - 419200 - - - 1.4074 - 2.366 0.449 - 265.7 1 2 0 0.0017 11 0 0 0 1.96E+07 2.48E+07 - - - 5.9919 0.9224 230117_WJC_METTL3_WT_vs_EV_F01.09761.09761.2 14.9 12-Apr K.LVAQLYK.L "sp|O75390|CISY_HUMAN,tr|H0YIC4|H0YIC4_HUMAN,tr|B4DJV2|B4DJV2_HUMAN,tr|A0A0C4DGI3|A0A0C4DGI3_HUMAN" 4 833.5011 1.42 528 9761 2 833.501936 417.7578 "Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2" 8.59 2453.8 - 329011 - - - 1.015 - 0.96 0.123 - 30.5 35 2 0 0.0008 7 0 0 0 4.12E+07 2.90E+07 - - - -0.8699 0.9949 230117_WJC_METTL3_WT_vs_EV_F01.09762.09762.2 0.296 14-Jul K.LIPDSIGK[136.11].D "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 6 849.5051 0.33 529 9762 2 849.504815 425.7598 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.84 2453.9 - 86421.2 - - - -0.3579 - 1.111 0.279 - 97.8 1 2 0 -0.0003 8 0 0 0 4.53E+06 1.39E+07 - - - 1.4191 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.09776.09776.2 0.0596 16-Aug K.IVVVTAGVR[166.11].Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 922.5839 0.82 535 9776 2 922.584674 462.2992 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2455.9 - 565176 - - - 0.8151 - 1.619 0.249 - 188.5 1 2 0 0.0008 9 0 0 0 1.81E+08 2.21E+08 - - - 2.2738 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.09794.09794.2 0.0769 16-Sep K.IVVVTAGVR.Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 912.5757 0.81 538 9794 2 912.575656 457.2951 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2458.9 - 1.65E+06 - - - 0.0044 - 1.909 0.272 - 348.6 1 2 0 0 9 0 0 0 1.80E+08 2.21E+08 - - - 2.9206 0.997 230117_WJC_METTL3_WT_vs_EV_F01.09807.09807.2 0.433 12-Jun K.LEATMLR[166.11].L "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 842.4559 3.09 540 9807 2 842.456967 422.2352 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6 2460.9 - 553516 - - - 1.2143 - 1.326 0.195 - 85.6 1 2 0 0.001 7 0 0 0 9.81E+07 3.18E+07 - - - 1.375 0.9959 230117_WJC_METTL3_WT_vs_EV_F01.09813.09813.2 0.279 12-Jul K.LEATMLR.L "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 832.4477 1.22 542 9813 2 832.447921 417.2311 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6 2461.7 - 553621 - - - 0.2967 - 1.467 0.143 - 171 1 2 0 0.0002 7 0 0 0 3.67E+07 3.00E+07 - - - 1.3114 0.9781 230117_WJC_METTL3_WT_vs_EV_F01.09815.09815.2 4.9 12-Jun K.ILLSPER[166.11].V "sp|P24928|RPB1_HUMAN,tr|H3BVE3|H3BVE3_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 3 836.4995 0.98 543 9815 2 836.499778 419.257 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 6 2462 - 510362 - - - 0.3048 - 1.301 0.03 - 113.7 1 2 0 0.0003 7 0 0 0 1.17E+08 1.20E+08 - - - 0.0963 0.8624 230117_WJC_METTL3_WT_vs_EV_F01.09831.09831.2 0.535 12-Aug N.LNTLIQR.S "sp|P20036|DPA1_HUMAN,sp|Q00839|HNRPU_HUMAN,sp|Q8IUG5|MY18B_HUMAN,tr|A0A140T914|A0A140T914_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|F5H6I8|F5H6I8_HUMAN,tr|A0A140T9R4|A0A140T9R4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A140T9D6|A0A140T9D6_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A140T9Y9|A0A140T9Y9_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A140T9H1|A0A140T9H1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A140T9U4|A0A140T9U4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A140T9F8|A0A140T9F8_HUMAN,tr|J3KQ99|J3KQ99_HUMAN" 24 856.5131 0.24 546 9831 2 856.513426 429.2638 "HLA class II histocompatibility antigen, DP alpha 1 chain OS=Homo sapiens OX=9606 GN=HLA-DPA1 PE=1 SV=1" 9.75 2464.4 - 2.63E+06 - - - 0.4378 - 1.76 0.142 - 287.6 1 1 0 0.0004 7 0 0 0 1.06E+08 4.47E+08 - - - 1.8809 0.997 230117_WJC_METTL3_WT_vs_EV_F01.09835.09835.2 3.02 12-Jun K.ILLSPER.V "sp|P24928|RPB1_HUMAN,tr|H3BVE3|H3BVE3_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 3 826.4913 0.98 550 9835 2 826.492613 414.2529 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 6 2464.8 - 651215 - - - 1.6455 - 1.379 0.18 - 124.3 1 2 0 0.0014 7 0 0 0 1.18E+08 1.21E+08 - - - 1.3883 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.09839.09839.2 0.00131 22-Sep R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 999 552 9839 2 1380.640907 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2465.3 - 90222.3 - - - 0.0123 - 1.965 0.457 - 237.9 1 2 0 0 12 0 0 0 9.03E+06 0.00E+00 - - - 4.1937 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.09856.09856.2 0.0533 18-Aug K.IGAVEEELNR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1138.5858 0.55 554 9856 2 1138.589254 570.3002 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.25 2468.1 - 131554 - - - 3.0582 - 1.793 0.264 - 193.9 1 2 0 0.0035 10 0 0 0 6.80E+06 1.24E+07 - - - 2.6196 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.09863.09863.2 0.00279 12-Aug R.IPGIYGR.L "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 774.4388 1.06 556 9863 2 774.438292 388.2267 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.75 2469.1 - 332311 - - - -0.6869 - 1.642 0.248 - 215.8 1 2 0 -0.0005 7 0 0 0 1.58E+08 1.49E+08 - - - 2.4439 0.9311 230117_WJC_METTL3_WT_vs_EV_F01.09904.09904.2 2.33 12-Jun R.MIVGTLK[136.11].G "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 768.4659 2.62 563 9904 2 768.465665 385.2402 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 8.5 2475.5 - 678804 - - - -0.3019 - 1.106 0.061 - 123.7 4 2 0 -0.0002 7 0 0 0 4.53E+08 1.72E+08 - - - -0.4582 0.9812 230117_WJC_METTL3_WT_vs_EV_F01.09908.09908.2 4.93 12-Jun R.MIVGTLK.G "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 760.4517 2.54 564 9908 2 760.451728 381.2331 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 8.5 2476 - 1.79E+06 - - - 0.0408 - 1.091 0.131 - 152 1 2 0 0 7 0 0 0 4.34E+08 1.71E+08 - - - 0.2845 0.9928 230117_WJC_METTL3_WT_vs_EV_F01.09922.09922.2 1.89 12-Jun R.ILLEAAR[166.11].L "sp|P49189|AL9A1_HUMAN,sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 3 794.489 2.13 566 9922 2 794.489275 398.2518 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3 6 2478.3 - 489708 - - - 0.3977 - 1.429 0.092 - 122.1 1 2 0 0.0003 7 0 0 0 8.16E+07 3.82E+07 - - - 0.8515 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.09931.09931.2 0.404 18-Jun K.MLVSGAGDIK.L "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 989.5216 22.61 569 9931 2 989.521922 495.7681 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.59 2479.6 - 239565 - - - 0.3588 - 1.153 0.242 - 75.9 1 2 0 0.0004 10 0 0 0 1.69E+07 7.47E+05 - - - 1.2257 0.8824 230117_WJC_METTL3_WT_vs_EV_F01.10025.10025.2 0.0588 12-Aug G.IIEPSLR.Q "sp|P62987|RL40_HUMAN,tr|M0R1A4|M0R1A4_HUMAN,tr|M0QZ32|M0QZ32_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|M0R1M6|M0R1M6_HUMAN" 5 826.4913 1.23 580 10025 2 826.492174 414.2529 Ubiquitin-60S ribosomal protein L40 OS=Homo sapiens OX=9606 GN=UBA52 PE=1 SV=2 6 2495.1 - 1.48E+07 - - - 1.1143 - 1.771 0.14 - 241.4 1 1 0 0.0009 7 0 0 0 1.06E+09 8.59E+08 - - - 1.8857 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.10029.10029.2 0.0565 14-Sep R.VMGLVPAK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 821.4924 1.64 581 10029 2 821.49368 411.7535 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.72 2495.6 - 458740 - - - 1.5021 - 1.485 0.284 - 235.5 1 2 0 0.0012 8 0 0 0 5.41E+07 3.30E+07 - - - 2.3308 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.10076.10076.2 0.00464 12-Aug R.LMDVMAK.E sp|Q12874|SF3A3_HUMAN 1 806.403 3.16 589 10076 2 806.403372 404.2088 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2503.2 - 540419 - - - 0.4216 - 1.489 0.348 - 226.3 1 2 0 0.0003 7 0 0 0 1.59E+08 5.05E+07 - - - 2.8726 0.9846 230117_WJC_METTL3_WT_vs_EV_F01.10082.10082.2 0.016 22-Mar R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 6.77 591 10082 2 1452.642537 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2504.1 - 26491.6 - - - -0.6492 - 0.743 0.332 - 29.1 1 2 0 -0.0009 12 0 0 0 2.85E+07 4.20E+06 - - - 0.7112 0.999 230117_WJC_METTL3_WT_vs_EV_F01.10086.10086.2 0.0144 12-Jun R.LMDVMAK[136.11].E sp|Q12874|SF3A3_HUMAN 1 814.4172 3.16 592 10086 2 814.419183 408.2159 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2504.7 - 507224 - - - 2.3956 - 1.357 0.361 - 89 1 2 0 0.002 7 0 0 0 1.60E+08 5.05E+07 - - - 2.674 1 230117_WJC_METTL3_WT_vs_EV_F01.10093.10093.2 2.46E-08 22-Dec R.AQVQEFC[160.03]DYGTK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1444.6293 6.77 594 10093 2 1444.633227 723.3219 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2505.8 - 241050 - - - 2.7322 - 2.407 0.64 - 462.1 1 2 0 0.0039 12 0 0 0 2.85E+07 4.20E+06 - - - 6.078 0.9973 230117_WJC_METTL3_WT_vs_EV_F01.10111.10111.2 0.461 12-Jun -.MAAPILR.S sp|Q9Y2Z4|SYYM_HUMAN 1 770.4473 4.6 597 10111 2 770.448324 386.2309 "Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2" 9.5 2508.8 - 1.63E+06 - - - 1.3551 - 1.41 0.182 - 184.6 1 2 0 0.001 7 0 0 0 1.94E+08 4.21E+07 - - - 1.4736 0.9341 230117_WJC_METTL3_WT_vs_EV_F01.10122.10122.2 3.82 12-May -.MAAPILR[166.11].S sp|Q9Y2Z4|SYYM_HUMAN 1 780.4556 4.59 598 10122 2 780.455885 391.2351 "Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2" 9.5 2510.7 - 552316 - - - 0.4292 - 1.097 0.037 - 84.6 4 2 0 0.0003 7 0 0 0 1.93E+08 4.20E+07 - - - -0.6614 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.10163.10163.2 1.79 14-Sep R.IIAEALTR[166.11].V "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 5 895.5366 0.93 606 10163 2 895.538008 448.7756 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 2517.2 - 996931 - - - 1.5309 - 1.514 0.137 - 222.5 1 2 0 0.0014 8 0 0 0 5.89E+07 6.35E+07 - - - 1.3033 0.998 230117_WJC_METTL3_WT_vs_EV_F01.10196.10196.2 0.658 12-Aug K.EGIVALR[166.11].R sp|P40227|TCPZ_HUMAN 1 766.4577 0.52 613 10196 2 766.458388 384.2361 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 6.1 2522.4 - 1.50E+06 - - - 0.9524 - 1.653 0.148 - 322.1 1 2 0 0.0007 7 0 0 0 5.86E+07 1.12E+08 - - - 1.7264 0.9935 230117_WJC_METTL3_WT_vs_EV_F01.10207.10207.2 0.66 16-Jul K.VELQELNDR.F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1114.5619 2.77 616 10207 2 1114.565141 558.2882 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.14 2523.9 - 164628 - - - 2.9509 - 1.586 0.114 - 184.8 1 2 0 0.0033 9 0 0 0 2.31E+07 8.34E+06 - - - 1.2163 0.9023 230117_WJC_METTL3_WT_vs_EV_F01.10228.10228.2 1.31 12-Jun R.VLYSLAK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 792.4745 1.3 618 10228 2 792.470953 397.2445 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.56 2527.5 - 488531 - - - -4.5276 - 1.417 0.128 - 103.9 1 2 0 -0.0036 7 0 0 0 7.16E+07 5.53E+07 - - - 1.0897 0.9418 230117_WJC_METTL3_WT_vs_EV_F01.10273.10273.2 7.09 12-Jun R.VAPVLIR[166.11].E "sp|P30419|NMT1_HUMAN,sp|O60551|NMT2_HUMAN,tr|A0A7I2V3X4|A0A7I2V3X4_HUMAN,tr|A0A7I2V539|A0A7I2V539_HUMAN,tr|Q5VUC6|Q5VUC6_HUMAN,tr|A0A7I2V3U5|A0A7I2V3U5_HUMAN" 6 776.5148 0.77 625 10273 2 776.514052 389.2647 Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2 9.72 2534.6 - 268145 - - - -0.9362 - 1.078 0.103 - 122.4 2 2 0 -0.0007 7 0 0 0 3.43E+07 4.44E+07 - - - -0.095 0.9886 230117_WJC_METTL3_WT_vs_EV_F01.10277.10277.2 4.76 12-Jul R.LYTVVPR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 846.4963 1.63 627 10277 2 846.497694 424.2554 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 2535 - 1.03E+06 - - - 1.6007 - 1.11 0.138 - 194.8 1 2 0 0.0014 7 0 0 0 1.91E+08 1.17E+08 - - - 0.3905 0.9569 230117_WJC_METTL3_WT_vs_EV_F01.10292.10292.2 3.92 14-Jun K.MLVIEQC[160.03]K.N "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1019.5144 12.75 631 10292 2 1019.514992 510.7645 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.75 2537.2 - 90249.2 - - - 0.6062 - 0.977 0.082 - 113.5 1 2 0 0.0006 8 0 0 0 4.65E+06 3.65E+05 - - - -0.4237 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.10299.10299.2 0.0128 12-Jul R.LYTVVPR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 856.5046 1.63 633 10299 2 856.505948 429.2596 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 2538.2 - 2.11E+06 - - - 1.5633 - 1.361 0.279 - 195.5 1 2 0 0.0013 7 0 0 0 1.91E+08 1.17E+08 - - - 2.0779 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.10302.10302.2 0.0215 14-Sep K.IPAMTIAK[136.11].N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.503 2.16 634 10302 2 851.503328 426.7588 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2538.6 - 1.99E+06 - - - 0.3735 - 1.627 0.309 - 237.6 1 2 0 0.0003 8 0 0 0 2.56E+09 1.18E+09 - - - 2.7912 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.10306.10306.2 0.119 14-Aug K.IPAMTIAK.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.4888 2.16 636 10306 2 843.489337 422.7517 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2539.1 - 4.27E+06 - - - 0.6248 - 1.383 0.287 - 169.3 1 2 0 0.0005 8 0 0 0 2.56E+09 1.18E+09 - - - 2.1386 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.10338.10338.2 0.001 16-Aug R.VLPVYGGPK.G "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 928.5382 1.39 645 10338 2 928.536497 465.2764 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 8.56 2543.9 - 195879 - - - -1.8373 - 1.496 0.369 - 144 1 2 0 -0.0017 9 0 0 0 1.68E+07 1.20E+07 - - - 2.9312 0.9829 230117_WJC_METTL3_WT_vs_EV_F01.10376.10376.2 0.588 14-Aug R.LLTGPVVR[166.11].G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 863.5468 2.07 655 10376 2 863.544317 432.7807 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2549.3 - 5.14E+06 - - - -2.8846 - 1.497 0.202 - 197.1 1 2 0 -0.0025 8 0 0 0 3.81E+08 1.84E+08 - - - 1.749 0.9904 230117_WJC_METTL3_WT_vs_EV_F01.10424.10424.2 0.0388 16-Sep K.LSDGVAVLK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 908.5422 2.29 658 10424 2 908.538686 455.2784 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2557.2 - 2.61E+06 - - - -3.9041 - 1.83 0.305 - 176.8 1 2 0 -0.0035 9 0 0 0 2.51E+08 1.09E+08 - - - 3.0409 0.983 230117_WJC_METTL3_WT_vs_EV_F01.10502.10502.2 5.91 12-Aug R.LLAALER[166.11].R sp|Q96A98|TIP39_HUMAN 1 794.489 1.27 661 10502 2 794.487578 398.2518 Tuberoinfundibular peptide of 39 residues OS=Homo sapiens OX=9606 GN=PTH2 PE=1 SV=1 6 2570.4 - 7.89E+06 - - - -1.7382 - 1.757 0.073 - 201.2 3 2 0 -0.0014 7 0 0 0 1.69E+09 1.34E+09 - - - 1.1524 0.8898 230117_WJC_METTL3_WT_vs_EV_F01.10506.10506.2 2.87 12-Jun K.GDVQTIR.W sp|Q702N8|XIRP1_HUMAN 1 787.4188 999 662 10506 2 787.417482 394.7167 Xin actin-binding repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=XIRP1 PE=1 SV=1 5.84 2571 - 8.43E+06 - - - -1.6954 - 1.219 0.014 - 229.4 1 2 0 -0.0013 7 0 0 0 4.39E+08 0.00E+00 - - - -0.2285 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.10524.10524.2 0.000493 12-Jun R.LVDMMER.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 892.4147 1.16 665 10524 2 892.414507 447.2146 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 2573.7 - 3.33E+06 - - - -0.1703 - 1.423 0.426 - 128.9 1 2 0 -0.0002 7 0 0 0 2.60E+08 2.23E+08 - - - 3.3052 0.8482 230117_WJC_METTL3_WT_vs_EV_F01.10539.10539.2 0.00419 14-Sep K.PSPLLVGR.E "sp|Q13283|G3BP1_HUMAN,sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2R0|A0A7I2V2R0_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RGJ4|D6RGJ4_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|D6R9A4|D6R9A4_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|E5RI46|E5RI46_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 25 837.5072 1.14 668 10539 2 837.505519 419.7609 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 10.18 2575.9 - 1.94E+06 - - - -2.0525 - 1.745 0.373 - 331.1 1 1 0 -0.0017 8 0 0 0 1.45E+08 1.28E+08 - - - 3.4746 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.10545.10545.2 0.0739 12-Aug R.LVDMMER[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 902.4229 1.16 669 10545 2 902.422752 452.2187 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 2576.8 - 5.19E+06 - - - -0.1961 - 1.3 0.36 - 244.9 1 2 0 -0.0002 7 0 0 0 2.60E+08 2.23E+08 - - - 2.5312 0.9817 230117_WJC_METTL3_WT_vs_EV_F01.10560.10560.2 0.337 12-Aug K.LVVALSR[166.11].T "sp|Q9BPX3|CND3_HUMAN,tr|D6RA93|D6RA93_HUMAN" 2 766.494 0.01 671 10560 2 766.491431 384.2543 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 9.75 2579.1 - 2.30E+06 - - - -3.409 - 1.631 0.189 - 252 1 2 0 -0.0026 7 0 0 0 8.94E+05 8.80E+07 - - - 1.9862 0.995 230117_WJC_METTL3_WT_vs_EV_F01.10563.10563.2 1.5 12-Jun K.FIGELGK.L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 762.4276 2.2 672 10563 2 762.427578 382.2211 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2579.5 - 864208 - - - -0.0157 - 1.396 0.16 - 133.9 1 2 0 0 7 0 0 0 3.31E+08 1.50E+08 - - - 1.2798 0.9391 230117_WJC_METTL3_WT_vs_EV_F01.10580.10580.2 0.137 12-Jul K.FIGELGK[136.11].L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 770.4418 2.07 673 10580 2 770.437054 386.2282 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2582.4 - 2.04E+06 - - - -6.1471 - 1.508 0.285 - 183 1 2 0 -0.0047 7 0 0 0 3.09E+08 1.50E+08 - - - 2.4461 0.988 230117_WJC_METTL3_WT_vs_EV_F01.10606.10606.2 0.00874 14-Aug R.LGPLQVAR.V sp|P38117|ETFB_HUMAN 1 852.5181 2.63 677 10606 2 852.514697 427.2663 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 9.75 2586.4 - 5.22E+06 - - - -4.0351 - 1.764 0.285 - 279.5 1 2 0 -0.0034 8 0 0 0 3.23E+08 1.23E+08 - - - 2.8567 0.9933 230117_WJC_METTL3_WT_vs_EV_F01.10614.10614.2 0.473 12-Jul K.AIFDSLR.E "sp|Q15327|ANKR1_HUMAN,sp|A6NEQ2|F181B_HUMAN" 2 820.4443 215.79 678 10614 2 820.443986 411.2294 Ankyrin repeat domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKRD1 PE=1 SV=2 5.88 2587.7 - 834999 - - - -0.3864 - 1.258 0.196 - 154.7 1 2 0 -0.0003 7 0 0 0 1.57E+08 7.26E+05 - - - 1.2158 0.9625 230117_WJC_METTL3_WT_vs_EV_F01.10651.10651.2 1.06 12-Jul K.LDIAAVR[166.11].A "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 766.4577 0.06 686 10651 2 766.455743 384.2361 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 5.84 2593.1 - 1.38E+06 - - - -2.4985 - 1.471 0.087 - 160.3 1 2 0 -0.0019 7 0 0 0 4.00E+06 6.49E+07 - - - 0.9059 0.9853 230117_WJC_METTL3_WT_vs_EV_F01.10673.10673.2 2.04 12-Jun K.AIFAGYK.R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 768.417 0.81 688 10673 2 768.417688 385.2158 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2596.7 - 846739 - - - 0.8615 - 1.139 0.107 - 109.1 1 2 0 0.0007 7 0 0 0 2.80E+08 3.47E+08 - - - 0.2435 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.10685.10685.2 0.0848 12-Jun K.AIFAGYK[136.11].R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 776.4312 0.81 691 10685 2 776.431904 389.2229 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2598.5 - 2.95E+06 - - - 0.8732 - 1.245 0.199 - 156.8 1 2 0 0.0007 7 0 0 0 2.80E+08 3.47E+08 - - - 1.2049 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.10699.10699.2 0.0312 14-Jul K.YVPLADVK[136.11].S "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 911.5208 0.74 694 10699 2 911.521419 456.7677 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.83 2600.6 - 725550 - - - 0.7131 - 1.328 0.305 - 187.9 1 2 0 0.0006 8 0 0 0 7.36E+07 9.94E+07 - - - 2.1491 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.10704.10704.2 0.0138 16-Aug R.QEYEQLIAK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1120.5764 0.4 695 10704 2 1120.578918 561.2955 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.53 2601.4 - 442800 - - - 2.2114 - 1.665 0.343 - 227.4 1 2 0 0.0025 9 0 0 0 1.52E+07 3.82E+07 - - - 3.0486 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.10711.10711.2 0.163 12-Jul R.LPPDVLR.W sp|P78527|PRKDC_HUMAN 1 808.4807 13.77 696 10711 2 808.480965 405.2476 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2602.5 - 1.39E+06 - - - 0.3414 - 1.39 0.179 - 172.9 1 2 0 0.0003 7 0 0 0 1.72E+09 1.25E+08 - - - 1.4064 0.9945 230117_WJC_METTL3_WT_vs_EV_F01.10718.10718.2 0.729 14-Aug K.LLEATELK[136.11].G "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 923.5419 1.13 698 10718 2 923.543702 462.7782 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 2603.5 - 1.41E+06 - - - 1.9533 - 1.48 0.101 - 161.9 1 2 0 0.0018 8 0 0 0 6.13E+07 5.45E+07 - - - 0.9688 0.9927 230117_WJC_METTL3_WT_vs_EV_F01.10725.10725.2 1.09 12-Jul R.VLISSLK.D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 758.4902 0.77 700 10725 2 758.490683 380.2524 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2604.4 - 738768 - - - 0.6487 - 1.371 0.099 - 164.9 1 2 0 0.0005 7 0 0 0 1.25E+08 1.61E+08 - - - 0.7719 0.9915 230117_WJC_METTL3_WT_vs_EV_F01.10729.10729.2 0.539 12-Jun K.VLLAEYK.N sp|Q16513|PKN2_HUMAN 1 834.4851 0 701 10729 2 834.486032 418.2498 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 5.97 2605 - 1.15E+06 - - - 1.1109 - 1.231 0.121 - 120.4 1 2 0 0.0009 7 0 0 0 7.71E+07 1.97E+10 - - - 0.5929 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.10750.10750.2 0.203 12-May K.SVLTPLR[166.11].G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 794.489 1.14 706 10750 2 794.489464 398.2518 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2608.1 - 1.03E+06 - - - 0.6356 - 1.441 0.176 - 100.3 1 2 0 0.0005 7 0 0 0 6.64E+07 5.81E+07 - - - 1.4984 0.9938 230117_WJC_METTL3_WT_vs_EV_F01.10753.10753.2 0.142 12-Jun K.SVLTPLR.G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 784.4807 1.17 707 10753 2 784.480872 393.2476 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2608.5 - 1.11E+06 - - - 0.2333 - 1.103 0.225 - 136.1 1 2 0 0.0002 7 0 0 0 6.78E+07 5.81E+07 - - - 1.0134 0.9902 230117_WJC_METTL3_WT_vs_EV_F01.10759.10759.2 1.41 12-Jun R.VLISSLK[136.11].D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 766.5044 1.16 709 10759 2 766.505118 384.2595 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2609.3 - 1.93E+06 - - - 0.9485 - 1.269 0.097 - 153.6 1 2 0 0.0007 7 0 0 0 1.19E+08 1.02E+08 - - - 0.5121 0.9562 230117_WJC_METTL3_WT_vs_EV_F01.10763.10763.2 1.49 12-Apr R.LLDVYEK.E "sp|Q96EF6|FBX17_HUMAN,tr|M0R2C6|M0R2C6_HUMAN,tr|M0QZ95|M0QZ95_HUMAN" 3 878.4749 1.5 711 10763 2 878.474764 440.2447 F-box only protein 17 OS=Homo sapiens OX=9606 GN=FBXO17 PE=1 SV=1 4.37 2609.8 - 229820 - - - -0.1935 - 0.933 0.151 - 37.4 2 2 0 -0.0002 7 0 0 0 1.21E+07 8.08E+06 - - - -0.198 0.9934 230117_WJC_METTL3_WT_vs_EV_F01.10765.10765.2 0.383 14-Jul R.ILLAVNGK.V sp|O15173|PGRC2_HUMAN 1 826.5276 1.67 712 10765 2 826.527349 414.2711 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.75 2610 - 449972 - - - -0.3509 - 1.225 0.212 - 100.7 1 2 0 -0.0003 8 0 0 0 4.63E+07 2.77E+07 - - - 1.2188 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.10778.10778.2 3.38 12-Jul R.IVEGILK.R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 770.4902 2.02 717 10778 2 770.49173 386.2524 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 2611.8 - 893588 - - - 1.9974 - 1.321 0.188 - 114.4 1 2 0 0.0015 7 0 0 0 7.39E+08 3.66E+08 - - - 1.3112 0.99 230117_WJC_METTL3_WT_vs_EV_F01.10779.10779.2 4.64 12-May R.IVEGILK[136.11].R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 778.5044 2.02 718 10779 2 778.504927 390.2595 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 2611.9 - 583994 - - - 0.6885 - 1.242 0.167 - 48.6 9 2 0 0.0005 7 0 0 0 7.39E+08 3.66E+08 - - - 0.5347 0.9911 230117_WJC_METTL3_WT_vs_EV_F01.10787.10787.2 1.23 14-Jul R.ILLAVNGK[136.11].V sp|O15173|PGRC2_HUMAN 1 834.5418 1.87 721 10787 2 834.543281 418.2782 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.75 2613.1 - 381782 - - - 1.7279 - 1.164 0.146 - 87.8 1 2 0 0.0014 8 0 0 0 5.20E+07 2.78E+07 - - - 0.5769 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.10801.10801.2 0.000132 22-Aug R.HVFLTGPPGVGK.T "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1207.6713 4.41 726 10801 2 1207.674007 604.8429 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.76 2615.2 - 198548 - - - 2.2059 - 1.498 0.465 - 125.2 1 2 0 0.0027 12 0 0 0 8.40E+06 1.91E+06 - - - 3.538 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.10804.10804.2 0.0398 12-Sep K.MGITPLR.N "sp|Q12789|TF3C1_HUMAN,sp|O43325|LYRM1_HUMAN,tr|H3BNA8|H3BNA8_HUMAN" 3 786.4422 1.1 727 10804 2 786.443933 394.2284 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 9.5 2615.6 - 719878 - - - 2.21 - 1.811 0.273 - 301.5 1 2 0 0.0017 7 0 0 0 6.77E+07 6.18E+07 - - - 2.9386 0.9515 230117_WJC_METTL3_WT_vs_EV_F01.10811.10811.2 5.68 14-Jun R.ILVGSLEK.N "sp|P51003|PAPOA_HUMAN,sp|Q9NRJ5|PAPOB_HUMAN,tr|G3XAH6|G3XAH6_HUMAN" 3 857.5222 1.08 731 10811 2 857.524231 429.7684 Poly(A) polymerase alpha OS=Homo sapiens OX=9606 GN=PAPOLA PE=1 SV=4 6 2616.5 - 313414 - - - 2.3463 - 1.233 0.034 - 75.9 6 2 0 0.002 8 0 0 0 1.19E+07 1.10E+07 - - - -0.4244 0.999 230117_WJC_METTL3_WT_vs_EV_F01.10819.10819.2 0.0433 18-Aug R.IITEGFEAAK.E sp|P40227|TCPZ_HUMAN 1 1077.5706 10.57 734 10819 2 1077.572855 539.7926 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 2617.6 - 527211 - - - 2.0685 - 1.68 0.269 - 132.6 1 2 0 0.0022 10 0 0 0 3.67E+07 3.47E+06 - - - 2.4752 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.10825.10825.2 9.25E-05 26-Oct R.SLYASSPGGVYATR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1427.7045 1.6 736 10825 2 1427.7077 714.8595 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2618.5 - 93637.6 - - - 2.2456 - 1.904 0.512 - 270.2 1 2 0 0.0032 14 0 0 0 6.69E+06 4.17E+06 - - - 4.4376 0.9739 230117_WJC_METTL3_WT_vs_EV_F01.10832.10832.2 1.17 14-Jun R.VIQALAMK[136.11].G "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 880.5296 1.2 738 10832 2 880.532878 441.2721 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.72 2619.5 - 390460 - - - 3.7682 - 1.343 0.143 - 81.3 9 2 0 0.0033 8 0 0 0 2.20E+07 1.83E+07 - - - 0.5593 0.9904 230117_WJC_METTL3_WT_vs_EV_F01.10836.10836.2 0.33 12-May R.LPPDVLR[166.11].W sp|P78527|PRKDC_HUMAN 1 818.489 1.61 740 10836 2 818.491016 410.2518 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2620.1 - 728654 - - - 2.5132 - 1.211 0.205 - 67.5 9 2 0 0.0021 7 0 0 0 1.42E+08 8.83E+07 - - - 0.7348 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.10847.10847.2 6.00E-05 26-Sep R.SLYASSPGGVYATR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1437.7128 1.6 744 10847 2 1437.718903 719.8637 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2621.7 - 144602 - - - 4.27 - 1.917 0.517 - 147.3 1 2 0 0.0061 14 0 0 0 6.69E+06 4.17E+06 - - - 4.4907 0.9956 230117_WJC_METTL3_WT_vs_EV_F01.10852.10852.2 0.0746 12-Jun R.TFLVGER[166.11].V sp|P26641|EF1G_HUMAN 1 830.4526 0.88 747 10852 2 830.454598 416.2336 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.66 2622.4 - 456777 - - - 2.4384 - 1.289 0.197 - 135.3 1 2 0 0.002 7 0 0 0 1.74E+07 1.99E+07 - - - 1.2998 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.10857.10857.2 0.043 16-Jun K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 0.83 750 10857 2 983.57975 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2623 - 118501 - - - 3.4263 - 1.203 0.327 - 104.9 1 2 0 0.0034 9 0 0 0 8.89E+07 1.08E+08 - - - 1.9899 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.10858.10858.2 0.0729 12-Jul K.LTGMAFR.V "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 794.4109 0.73 751 10858 2 794.412747 398.2127 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 9.75 2623.1 - 670475 - - - 2.3325 - 1.624 0.253 - 128.8 1 2 0 0.0019 7 0 0 0 5.17E+06 7.11E+06 - - - 2.4455 0.9915 230117_WJC_METTL3_WT_vs_EV_F01.10862.10862.2 14.3 12-Jul R.LIITQVR.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 841.5385 1.01 753 10862 2 841.539873 421.7765 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 9.75 2623.6 - 9.18E+06 - - - 1.5864 - 1.413 0.062 - 181.5 1 2 0 0.0013 7 0 0 0 3.77E+08 3.73E+08 - - - 0.5939 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.10869.10869.2 0.0413 14-Aug R.VIQALAMK.G "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 872.5154 1.2 757 10869 2 872.516172 437.265 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.72 2624.4 - 740251 - - - 0.9306 - 1.728 0.401 - 165.2 1 2 0 0.0008 8 0 0 0 2.20E+07 1.83E+07 - - - 3.6522 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.10872.10872.2 0.000623 16-Oct K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 0.83 760 10872 2 993.58539 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2624.8 - 290299 - - - 0.7448 - 2.077 0.325 - 311.8 1 2 0 0.0007 9 0 0 0 8.89E+07 1.08E+08 - - - 3.5558 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.10879.10879.2 0.419 12-Jul K.LTGMAFR[166.11].V "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 804.4192 2.74 763 10879 2 804.419871 403.2169 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 9.75 2625.8 - 7.36E+06 - - - 0.8789 - 1.62 0.209 - 175.4 1 2 0 0.0007 7 0 0 0 1.62E+10 5.90E+09 - - - 2.113 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.10882.10882.2 5.87E-05 14-Sep K.MMDIVAAK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 877.4401 1.63 766 10882 2 877.440804 439.7273 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.59 2626.1 - 453406 - - - 0.7499 - 1.733 0.503 - 317.1 1 2 0 0.0007 8 0 0 0 1.65E+07 1.01E+07 - - - 4.4143 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.10886.10886.2 0.478 12-Aug R.MGLVMDR[166.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 830.4018 2.33 767 10886 2 830.400166 416.2082 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2626.7 - 427840 - - - -1.9677 - 1.679 0.212 - 276.2 1 2 0 -0.0016 7 0 0 0 1.66E+09 7.13E+08 - - - 2.2483 1 230117_WJC_METTL3_WT_vs_EV_F01.10887.10887.2 3.30E-05 22-Oct R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 768 10887 2 1474.777347 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2626.8 - 196308 - - - -0.438 - 2.057 0.495 - 210.5 1 2 0 -0.0006 12 0 0 0 3.76E+07 0.00E+00 - - - 4.5946 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.10888.10888.2 5.20E-05 20-Oct K.FGDPVVQSDMK.H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1221.57 0.68 769 10888 2 1221.571433 611.7923 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.21 2626.9 - 262972 - - - 1.1944 - 1.585 0.412 - 240.6 1 2 0 0.0015 11 0 0 0 1.20E+07 1.76E+07 - - - 3.3296 0.9969 230117_WJC_METTL3_WT_vs_EV_F01.10892.10892.2 0.598 12-Jun K.VLPTIPK[136.11].E "sp|P35606|COPB2_HUMAN,sp|Q8ND07|BBOF1_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 5 774.5095 3.69 770 10892 2 774.509744 388.262 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 8.72 2627.5 - 823449 - - - 0.346 - 1.109 0.291 - 116.6 1 2 0 0.0003 7 0 0 0 2.21E+08 5.98E+07 - - - 1.5181 0.9224 230117_WJC_METTL3_WT_vs_EV_F01.10904.10904.2 0.0992 12-Jul R.MGLVMDR.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 820.3935 2.33 775 10904 2 820.38837 411.204 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2629 - 3.03E+06 - - - -6.2897 - 1.273 0.333 - 185 1 2 0 -0.0052 7 0 0 0 1.66E+09 7.13E+08 - - - 2.2637 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.10931.10931.2 0.000688 20-Oct K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 3168.6 781 10931 2 1106.546274 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2633.1 - 368028 - - - -0.1157 - 2.027 0.431 - 251.7 1 2 0 -0.0001 11 0 0 0 2.87E+09 9.06E+05 - - - 4.1357 0.9934 230117_WJC_METTL3_WT_vs_EV_F01.10950.10950.2 0.46 12-May R.LILPEAK.V "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN,tr|A8MSZ8|A8MSZ8_HUMAN" 3 782.4902 1.35 784 10950 2 782.490783 392.2524 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 6 2636 - 2.22E+06 - - - 0.7566 - 1.021 0.232 - 92.3 1 2 0 0.0006 7 0 0 0 1.47E+08 1.09E+08 - - - 0.8202 0.9924 230117_WJC_METTL3_WT_vs_EV_F01.10952.10952.2 0.0606 16-Jul K.EIAEAYLGK.T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 992.5179 10.81 785 10952 2 992.517264 497.2662 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 2636.2 - 1.42E+06 - - - -0.6025 - 1.269 0.202 - 143.9 1 2 0 -0.0006 9 0 0 0 7.66E+07 7.09E+06 - - - 1.222 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.10954.10954.2 0.0398 14-Aug R.VITALVER.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 899.544 0.37 786 10954 2 899.543715 450.7793 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2636.4 - 1.42E+06 - - - -0.3357 - 1.662 0.248 - 209.7 1 2 0 -0.0003 8 0 0 0 3.90E+09 1.06E+10 - - - 2.4048 0.9866 230117_WJC_METTL3_WT_vs_EV_F01.10966.10966.2 3.8 14-Jun R.LLVVTDPR[166.11].A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 921.5523 2.85 789 10966 2 921.553572 461.7834 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.84 2638.2 - 548820 - - - 1.3944 - 1.179 0.099 - 104 1 2 0 0.0013 8 0 0 0 2.28E+09 8.02E+08 - - - 0.2684 0.9792 230117_WJC_METTL3_WT_vs_EV_F01.10970.10970.2 0.781 14-Jul R.VFVNPSLR[166.11].V sp|Q9HBH1|DEFM_HUMAN 1 940.537 1.06 791 10970 2 940.537462 471.2758 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 9.72 2638.7 - 1.69E+06 - - - 0.522 - 1.155 0.081 - 117.4 1 2 0 0.0005 8 0 0 0 4.78E+08 4.53E+08 - - - 0.0737 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.10985.10985.2 0.0418 12-Jun K.YGDAFIR[166.11].G sp|P62312|LSM6_HUMAN 1 850.4213 2.39 794 10985 2 850.421455 426.2179 U6 snRNA-associated Sm-like protein LSm6 OS=Homo sapiens OX=9606 GN=LSM6 PE=1 SV=1 5.84 2641.1 - 1.17E+06 - - - 0.214 - 1.481 0.166 - 107.8 1 2 0 0.0002 7 0 0 0 1.54E+08 6.43E+07 - - - 1.5114 0.9944 230117_WJC_METTL3_WT_vs_EV_F01.10994.10994.2 0.572 14-Aug R.AALLVPPR.Y sp|Q99959|PKP2_HUMAN 1 835.528 36.68 798 10994 2 835.5257 418.7713 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 9.79 2642.2 - 1.02E+06 - - - -2.7204 - 1.725 0.285 - 168.1 1 2 0 -0.0023 8 0 0 0 3.62E+08 9.87E+06 - - - 2.7897 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.11004.11004.2 0.728 12-Jul R.LNELLVK.A "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L253|I3L253_HUMAN" 3 827.5117 2.14 801 11004 2 827.511861 414.7631 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2643.5 - 2.40E+06 - - - 0.2501 - 1.688 0.156 - 151.8 1 2 0 0.0002 7 0 0 0 7.65E+08 3.57E+08 - - - 1.852 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.11006.11006.2 0.0528 14-Sep R.VITALVER[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 909.5523 0.37 803 11006 2 909.552308 455.7834 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2643.7 - 2.15E+08 - - - 0.0231 - 1.881 0.309 - 282.1 1 2 0 0 8 0 0 0 3.90E+09 1.06E+10 - - - 3.2288 0.9947 230117_WJC_METTL3_WT_vs_EV_F01.11012.11012.2 0.0486 12-Jun K.AC[160.03]TILLR.G "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 845.4793 12.02 806 11012 2 845.478971 423.7469 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 8.29 2644.4 - 3.43E+06 - - - -0.3998 - 1.165 0.256 - 218.9 1 2 0 -0.0003 7 0 0 0 5.33E+08 4.44E+07 - - - 1.4156 0.9458 230117_WJC_METTL3_WT_vs_EV_F01.11050.11050.2 0.0327 14-Aug Q.VLVLAPTR[166.11].E "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 877.5625 0.91 818 11050 2 877.563507 439.7885 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.72 2649.8 - 886757 - - - 1.1954 - 1.772 0.269 - 265.3 1 1 0 0.001 8 0 0 0 1.57E+08 1.72E+08 - - - 2.753 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.11063.11063.2 0.182 14-Aug R.VITALVER[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 909.5523 0.37 820 11063 2 909.554063 455.7834 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2651.8 - 2.31E+07 - - - 1.9526 - 1.731 0.277 - 198.8 1 2 0 0.0018 8 0 0 0 3.90E+09 1.06E+10 - - - 2.7412 0.9929 230117_WJC_METTL3_WT_vs_EV_F01.11072.11072.2 0.0445 22-Jun K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 2.25 823 11072 2 1222.66869 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2653.1 - 119615 - - - 3.1268 - 1.18 0.237 - 81.8 1 2 0 0.0038 12 0 0 0 1.10E+08 4.89E+07 - - - 1.2258 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.11081.11081.2 0.535 14-Aug K.IEISELNR.V "sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 2 972.524 144 827 11081 2 972.525101 487.2693 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2654.3 - 329406 - - - 1.1218 - 1.534 0.134 - 207.3 1 2 0 0.0011 8 0 0 0 8.44E+07 5.86E+05 - - - 1.3208 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.11083.11083.2 6.03E-05 22-Oct K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 2.25 828 11083 2 1214.65481 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2654.5 - 359735 - - - 3.4109 - 2.175 0.421 - 328.8 1 2 0 0.0041 12 0 0 0 1.10E+08 4.89E+07 - - - 4.1937 0.9922 230117_WJC_METTL3_WT_vs_EV_F01.11092.11092.2 0.589 12-Jul K.ALLLEAK[136.11].Q sp|Q9UJV9|DDX41_HUMAN 1 764.4887 0.09 831 11092 2 764.490569 383.2516 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 6.05 2655.8 - 2.34E+06 - - - 2.3911 - 1.452 0.084 - 213.6 1 2 0 0.0018 7 0 0 0 2.29E+07 2.57E+08 - - - 0.8425 0.9949 230117_WJC_METTL3_WT_vs_EV_F01.11094.11094.2 0.201 12-Jun R.LISVLNK[136.11].S "sp|Q9Y450|HBS1L_HUMAN,tr|H0YDX7|H0YDX7_HUMAN,tr|B7Z524|B7Z524_HUMAN,tr|J3QT46|J3QT46_HUMAN" 4 793.5153 0.47 832 11094 2 793.517387 397.7649 HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1 8.75 2656 - 851545 - - - 2.6427 - 1.256 0.203 - 92 1 2 0 0.0021 7 0 0 0 4.56E+07 9.78E+07 - - - 1.2619 0.9539 230117_WJC_METTL3_WT_vs_EV_F01.11096.11096.2 0.804 12-Jun R.LIPTELR[166.11].R "sp|Q96G21|IMP4_HUMAN,tr|F8WCN0|F8WCN0_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN" 4 850.5152 1.4 833 11096 2 850.518419 426.2649 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2656.2 - 198017 - - - 3.8165 - 1.164 0.118 - 96.7 3 2 0 0.0032 7 0 0 0 3.05E+08 2.18E+08 - - - 0.1796 0.996 230117_WJC_METTL3_WT_vs_EV_F01.11099.11099.2 0.109 12-Jul R.LISVLNK.S "sp|Q9Y450|HBS1L_HUMAN,tr|H0YDX7|H0YDX7_HUMAN,tr|B7Z524|B7Z524_HUMAN,tr|J3QT46|J3QT46_HUMAN" 4 785.5011 0.47 834 11099 2 785.503222 393.7578 HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1 8.75 2656.6 - 1.04E+06 - - - 2.7142 - 1.312 0.217 - 128.9 1 2 0 0.0021 7 0 0 0 4.56E+07 9.72E+07 - - - 1.5035 0.9882 230117_WJC_METTL3_WT_vs_EV_F01.11115.11115.2 0.134 12-May R.NMAPDLR[166.11].Q "sp|P35611|ADDA_HUMAN,tr|E7EV99|E7EV99_HUMAN,tr|E7ENY0|E7ENY0_HUMAN,tr|A0A804HL01|A0A804HL01_HUMAN,tr|A0A0A0MSR2|A0A0A0MSR2_HUMAN,tr|D6RAH3|D6RAH3_HUMAN,tr|D6RF25|D6RF25_HUMAN,tr|D6RJE2|D6RJE2_HUMAN" 8 825.4042 0.66 838 11115 2 825.406856 413.7094 Alpha-adducin OS=Homo sapiens OX=9606 GN=ADD1 PE=1 SV=2 5.84 2659.1 - 898961 - - - 3.1657 - 1.349 0.136 - 67.3 2 2 0 0.0026 7 0 0 0 5.59E+07 8.51E+07 - - - 0.8588 0.9898 230117_WJC_METTL3_WT_vs_EV_F01.11121.11121.2 0.613 14-Aug R.ILMAINGK[136.11].V sp|O00264|PGRC1_HUMAN 1 866.5139 0.92 840 11121 2 866.51639 434.2642 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 8.75 2660 - 2.27E+06 - - - 2.8632 - 1.3 0.135 - 168.2 1 2 0 0.0025 8 0 0 0 1.25E+08 1.36E+08 - - - 0.8286 0.9947 230117_WJC_METTL3_WT_vs_EV_F01.11134.11134.2 0.0651 12-Jun R.LIPTELR.R "sp|Q96G21|IMP4_HUMAN,tr|F8WCN0|F8WCN0_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN" 4 840.5069 1.09 844 11134 2 840.509232 421.2607 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2661.9 - 1.85E+06 - - - 2.7709 - 1.22 0.219 - 147.5 1 2 0 0.0023 7 0 0 0 2.24E+08 2.05E+08 - - - 1.2879 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.11144.11144.2 0.0126 20-Aug K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 11.17 847 11144 2 1106.550485 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2663.3 - 280933 - - - 3.6899 - 1.969 0.374 - 127.6 1 2 0 0.0041 11 0 0 0 2.68E+07 2.40E+06 - - - 3.6349 0.9902 230117_WJC_METTL3_WT_vs_EV_F01.11157.11157.2 2.27 12-May K.IIPVVVK[136.11].M "sp|Q96KG9|SCYL1_HUMAN,tr|E9PPN3|E9PPN3_HUMAN,tr|E9PK59|E9PK59_HUMAN,tr|E9PS17|E9PS17_HUMAN" 4 774.5459 1.59 852 11157 2 774.54732 388.2802 N-terminal kinase-like protein OS=Homo sapiens OX=9606 GN=SCYL1 PE=1 SV=1 8.75 2665.1 - 707713 - - - 1.8837 - 0.97 0.215 - 57.8 1 2 0 0.0015 7 0 0 0 5.15E+07 3.23E+07 - - - 0.532 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.11168.11168.2 0.116 20-Jun K.IGGIGTVPVGR.V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1024.6029 6.1 857 11168 2 1024.603172 513.3087 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2666.6 - 277115 - - - 0.2372 - 1.664 0.27 - 68.4 3 2 0 0.0002 11 0 0 0 1.18E+08 1.93E+07 - - - 2.1996 0.9804 230117_WJC_METTL3_WT_vs_EV_F01.11175.11175.2 0.494 12-May K.ILVIPSK.V sp|Q9Y2U8|MAN1_HUMAN 1 768.5109 1.13 859 11175 2 768.513809 385.2627 Inner nuclear membrane protein Man1 OS=Homo sapiens OX=9606 GN=LEMD3 PE=1 SV=2 8.75 2667.6 - 1.03E+06 - - - 3.7514 - 1.062 0.207 - 67.7 1 2 0 0.0029 7 0 0 0 2.22E+07 1.96E+07 - - - 0.7596 0.9785 230117_WJC_METTL3_WT_vs_EV_F01.11178.11178.2 8.5 12-Jun K.FIEIAAR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 818.465 0.96 860 11178 2 818.464678 410.2398 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2668.1 - 7.55E+06 - - - -0.4398 - 1.112 0.136 - 91.9 1 2 0 -0.0004 7 0 0 0 3.87E+10 4.02E+10 - - - 0.3818 0.9813 230117_WJC_METTL3_WT_vs_EV_F01.11182.11182.2 1.33 12-Jul K.SVLIMGR.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 774.4422 1.4 862 11182 2 774.444741 388.2284 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.47 2668.6 - 584762 - - - 3.2875 - 1.237 0.117 - 138.5 1 2 0 0.0025 7 0 0 0 1.21E+08 8.63E+07 - - - 0.5783 0.9958 230117_WJC_METTL3_WT_vs_EV_F01.11220.11220.2 0.0147 12-Jul K.SVLIMGR[166.11].G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 784.4505 1.65 877 11220 2 784.450551 393.2325 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.47 2673.7 - 1.58E+06 - - - 0.1096 - 1.363 0.182 - 235 1 2 0 0.0001 7 0 0 0 1.18E+08 7.13E+07 - - - 1.3665 0.9959 230117_WJC_METTL3_WT_vs_EV_F01.11235.11235.2 0.0245 14-Aug K.IGVTVLSR.L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 843.5178 0.9 881 11235 2 843.516096 422.7662 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2675.8 - 2.64E+06 - - - -2.0225 - 1.688 0.275 - 188.6 1 2 0 -0.0017 8 0 0 0 5.13E+08 5.68E+08 - - - 2.6506 0.9766 230117_WJC_METTL3_WT_vs_EV_F01.11254.11254.2 1.13 12-Jul R.VYLGALK[136.11].Y sp|Q6P2Q9|PRP8_HUMAN 1 770.4782 1.04 884 11254 2 770.477571 386.2464 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.56 2678.7 - 1.75E+06 - - - -0.7852 - 1.235 0.103 - 190 1 2 0 -0.0006 7 0 0 0 2.96E+08 2.85E+08 - - - 0.4704 0.9956 230117_WJC_METTL3_WT_vs_EV_F01.11273.11273.2 0.281 12-Jul R.VTVPLVR[166.11].R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 792.5097 0.96 890 11273 2 792.508749 397.2621 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2681.4 - 4.69E+06 - - - -1.1924 - 1.469 0.239 - 220.8 1 2 0 -0.0009 7 0 0 0 5.10E+08 5.33E+08 - - - 2.0245 0.9683 230117_WJC_METTL3_WT_vs_EV_F01.11274.11274.2 1.56 14-Jun R.ILMGSTLR[166.11].K "sp|P10644|KAP0_HUMAN,sp|P31321|KAP1_HUMAN,tr|K7EM13|K7EM13_HUMAN,tr|C9JSK5|C9JSK5_HUMAN,tr|K7EKR1|K7EKR1_HUMAN,tr|K7EPB2|K7EPB2_HUMAN,tr|H7BYW5|H7BYW5_HUMAN" 7 899.5138 1.75 891 11274 2 899.513016 450.7642 cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1A PE=1 SV=1 9.75 2681.6 - 797786 - - - -0.8638 - 1.151 0.112 - 96.8 1 2 0 -0.0008 8 0 0 0 4.71E+07 2.70E+07 - - - 0.2921 0.968 230117_WJC_METTL3_WT_vs_EV_F01.11278.11278.2 0.475 14-Jun R.VITALVER[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 909.5523 0.77 893 11278 2 909.551253 455.7834 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2682 - 368211 - - - -1.1368 - 1.302 0.095 - 78.4 2 2 0 -0.001 8 0 0 0 2.41E+07 3.14E+07 - - - 0.4038 0.9956 230117_WJC_METTL3_WT_vs_EV_F01.11285.11285.2 0.113 12-Jul R.VTVPLVR.R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 782.5014 0.96 895 11285 2 782.500573 392.258 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2683 - 4.73E+06 - - - -1.0875 - 1.466 0.232 - 206.7 1 2 0 -0.0009 7 0 0 0 5.12E+08 5.35E+08 - - - 1.9664 0.8929 230117_WJC_METTL3_WT_vs_EV_F01.11293.11293.2 1.18 14-Jul K.LVPVLSAK[136.11].A "sp|P37837|TALDO_HUMAN,tr|F2Z393|F2Z393_HUMAN" 2 833.5466 1.36 896 11293 2 833.544392 417.7806 Transaldolase OS=Homo sapiens OX=9606 GN=TALDO1 PE=1 SV=2 8.75 2684.3 - 1.01E+06 - - - -2.6369 - 1.117 0.109 - 110.1 1 2 0 -0.0022 8 0 0 0 6.47E+07 4.77E+07 - - - 0.1791 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.11308.11308.2 0.104 14-Aug K.IGVTVLSR[166.11].L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 853.5261 0.9 900 11308 2 853.526701 427.7703 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2686.4 - 2.94E+06 - - - 0.7369 - 1.723 0.27 - 169.3 1 2 0 0.0006 8 0 0 0 5.13E+08 5.68E+08 - - - 2.6759 0.9901 230117_WJC_METTL3_WT_vs_EV_F01.11314.11314.2 1.21 12-Jul K.LPYSTFR.T "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 882.46 1.15 901 11314 2 882.461368 442.2373 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.75 2687.4 - 462517 - - - 1.6035 - 1.072 0.166 - 167.8 1 2 0 0.0014 7 0 0 0 2.09E+08 1.82E+08 - - - 0.4869 0.9876 230117_WJC_METTL3_WT_vs_EV_F01.11329.11329.2 0.0156 14-Aug K.VGDFGLAR.E "sp|P21127|CD11B_HUMAN,sp|Q9UQ88|CD11A_HUMAN,sp|Q13882|PTK6_HUMAN,tr|Q5QPR4|Q5QPR4_HUMAN,tr|A0A0D9SER5|A0A0D9SER5_HUMAN,tr|A0A0D9SEN2|A0A0D9SEN2_HUMAN,tr|Q5QPR3|Q5QPR3_HUMAN,tr|A0A0D9SEI3|A0A0D9SEI3_HUMAN" 8 833.4396 1.4 908 11329 2 833.441869 417.7271 Cyclin-dependent kinase 11B OS=Homo sapiens OX=9606 GN=CDK11B PE=1 SV=4 5.81 2689.3 - 382979 - - - 2.78 - 1.415 0.077 - 147.6 1 2 0 0.0023 8 0 0 0 1.58E+07 1.13E+07 - - - 0.6559 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.11334.11334.2 0.118 12-Jun K.LPYSTFR[166.11].T "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 892.4682 1.15 911 11334 2 892.469951 447.2414 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.75 2689.9 - 1.32E+06 - - - 1.9362 - 1.15 0.254 - 152.7 1 2 0 0.0017 7 0 0 0 2.09E+08 1.82E+08 - - - 1.3593 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.11371.11371.2 2.79E-05 18-Aug K.NGQDLGVAFK[136.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1055.5491 1.44 924 11371 2 1055.550905 528.7818 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2695.2 - 264462 - - - 1.7015 - 1.907 0.377 - 264.8 1 2 0 0.0018 10 0 0 0 6.60E+07 4.58E+07 - - - 3.6268 0.9403 230117_WJC_METTL3_WT_vs_EV_F01.11375.11375.2 0.0564 14-Sep K.LTGVFAPR.P "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 859.4916 1.01 927 11375 2 859.493257 430.7531 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2695.7 - 4.84E+07 - - - 1.9418 - 1.768 0.267 - 333.6 1 1 0 0.0017 8 0 0 0 2.60E+09 2.57E+09 - - - 2.7312 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.11382.11382.2 0.663 12-Jul K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 5.82 929 11382 2 828.474506 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2696.8 - 3.40E+06 - - - 1.446 - 1.559 0.157 - 192.1 1 2 0 0.0012 7 0 0 0 1.74E+09 2.98E+08 - - - 1.6072 0.9849 230117_WJC_METTL3_WT_vs_EV_F01.11384.11384.2 0.122 12-Jun R.LVAFPTR.V "sp|O00258|GET1_HUMAN,tr|A0A3B3IT79|A0A3B3IT79_HUMAN,tr|A0A3B3ISE5|A0A3B3ISE5_HUMAN,tr|H7BYE5|H7BYE5_HUMAN,tr|B7Z1T1|B7Z1T1_HUMAN,tr|H7C384|H7C384_HUMAN,tr|A0A3B3ISE9|A0A3B3ISE9_HUMAN" 7 802.4701 2.68 930 11384 2 802.472305 402.2423 Guided entry of tail-anchored proteins factor 1 OS=Homo sapiens OX=9606 GN=GET1 PE=1 SV=2 9.75 2697 - 595990 - - - 2.7179 - 1.371 0.103 - 107.9 5 2 0 0.0022 7 0 0 0 3.86E+07 1.44E+07 - - - 0.4886 0.994 230117_WJC_METTL3_WT_vs_EV_F01.11396.11396.2 0.0881 14-Sep R.NLLLAGAK[136.11].V sp|Q9P2R3|ANFY1_HUMAN 1 806.5105 4.69 934 11396 2 806.512301 404.2625 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 8.75 2698.6 - 357904 - - - 2.1847 - 1.601 0.069 - 233.5 1 2 0 0.0018 8 0 0 0 1.08E+08 2.31E+07 - - - 0.9695 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.11402.11402.2 0.000764 14-Jul K.FGPALSVK[136.11].V "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 825.484 3.85 936 11402 2 825.485293 413.7493 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.75 2699.4 - 2.54E+06 - - - 1.5785 - 1.741 0.146 - 135.9 1 2 0 0.0013 8 0 0 0 3.44E+09 8.94E+08 - - - 1.7912 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.11411.11411.2 0.0473 12-Jul K.FMTDPIR.L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 878.432 0.94 940 11411 2 878.433275 440.2233 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2700.7 - 2.15E+06 - - - 1.4241 - 1.211 0.274 - 233.9 1 2 0 0.0013 7 0 0 0 1.65E+08 1.75E+08 - - - 1.671 0.992 230117_WJC_METTL3_WT_vs_EV_F01.11416.11416.2 1.25 12-Jul K.FMTDPIR[166.11].L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 888.4403 1.19 941 11416 2 888.441796 445.2274 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2701.4 - 3.16E+06 - - - 1.6906 - 1.143 0.161 - 187.3 1 2 0 0.0015 7 0 0 0 2.09E+08 1.76E+08 - - - 0.6532 0.958 230117_WJC_METTL3_WT_vs_EV_F01.11423.11423.2 2.61 14-May K.DGALDVKR.Q "sp|Q12912|IRAG2_HUMAN,tr|A0A1B0GU45|A0A1B0GU45_HUMAN" 2 872.4716 5.55 945 11423 2 872.474555 437.2431 "Inositol 1,4,5-triphosphate receptor associated 2 OS=Homo sapiens OX=9606 GN=IRAG2 PE=1 SV=3" 5.96 2702.3 - 2.73E+06 - - - 3.4099 - 1.193 0.109 - 83.2 5 2 0 0.003 8 0 0 0 4.48E+07 8.08E+06 - - - 0.0651 0.9627 230117_WJC_METTL3_WT_vs_EV_F01.11424.11424.2 4.14 14-Aug K.LGGLVIEK[136.11].Q "sp|Q92547|TOPB1_HUMAN,tr|A0A2R8YD63|A0A2R8YD63_HUMAN" 2 835.5259 0.34 946 11424 2 835.52676 418.7702 DNA topoisomerase 2-binding protein 1 OS=Homo sapiens OX=9606 GN=TOPBP1 PE=1 SV=3 6 2702.5 - 330698 - - - 1.0843 - 1.179 0.027 - 89.4 2 2 0 0.0009 8 0 0 0 5.54E+06 1.63E+07 - - - -0.3977 0.9827 230117_WJC_METTL3_WT_vs_EV_F01.11425.11425.2 8.23 12-Nov K.LAC[160.03]LLC[160.03]R[166.11].R "sp|P78332|RBM6_HUMAN,sp|P98175|RBM10_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 3 914.4705 0.39 947 11425 2 914.472234 458.2426 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 8.07 2702.6 - 862429 - - - 1.8426 - 1.331 0.026 - 587.4 1 2 0 0.0017 7 0 0 0 1.28E+07 3.30E+07 - - - 0.1385 0.9896 230117_WJC_METTL3_WT_vs_EV_F01.11432.11432.2 0.625 14-May K.VLEC[160.03]DIIK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 988.5263 0.51 950 11432 2 988.528651 495.2704 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 2703.6 - 288428 - - - 2.3601 - 1.116 0.205 - 61.7 4 2 0 0.0023 8 0 0 0 1.05E+07 2.04E+07 - - - 0.6165 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.11437.11437.2 4.49 14-Jul R.VLAVTAIR.E sp|P22102|PUR2_HUMAN 1 841.5385 2.43 952 11437 2 841.539839 421.7765 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2704.2 - 3.47E+06 - - - 1.546 - 1.655 0.09 - 206.9 1 2 0 0.0013 8 0 0 0 4.47E+08 1.84E+08 - - - 1.2248 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.11451.11451.2 0.62 14-Aug R.VLAVTAIR[166.11].E sp|P22102|PUR2_HUMAN 1 851.5468 2.43 956 11451 2 851.548122 426.7807 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2706.2 - 3.43E+06 - - - 1.5431 - 1.78 0.108 - 209.8 1 2 0 0.0013 8 0 0 0 4.47E+08 1.84E+08 - - - 1.5773 0.9736 230117_WJC_METTL3_WT_vs_EV_F01.11454.11454.2 0.16 18-May K.C[160.03]PFTGNVSIR[166.11].G "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1159.5683 0.92 957 11454 2 1159.572336 580.7915 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.25 2706.6 - 77253.4 - - - 3.4392 - 1.069 0.159 - 64.7 1 2 0 0.004 10 0 0 0 4.17E+06 4.52E+06 - - - 0.4004 0.9838 230117_WJC_METTL3_WT_vs_EV_F01.11461.11461.2 0.705 14-Jul K.VEVEVEVK.E "sp|Q96JP5|ZFP91_HUMAN,tr|H3BTR0|H3BTR0_HUMAN,tr|A0A0A6YYC7|A0A0A6YYC7_HUMAN" 3 929.507 99.38 959 11461 2 929.508153 465.7608 E3 ubiquitin-protein ligase ZFP91 OS=Homo sapiens OX=9606 GN=ZFP91 PE=1 SV=1 4.25 2707.6 - 3.27E+06 - - - 1.2802 - 1.419 0.006 - 126.3 1 2 0 0.0012 8 0 0 0 1.20E+09 1.21E+07 - - - 0.1404 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.11481.11481.2 0.000464 12-Aug K.MMEIMTR[166.11].E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 920.4157 0.86 968 11481 2 920.416827 461.2151 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2710.4 - 1.22E+06 - - - 1.1864 - 1.58 0.319 - 350.6 1 2 0 0.0011 7 0 0 0 1.90E+08 2.20E+08 - - - 2.8462 0.9958 230117_WJC_METTL3_WT_vs_EV_F01.11482.11482.2 0.0496 12-Jul K.MMEIMTR.E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 910.4075 0.86 969 11482 2 910.407837 456.211 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2710.5 - 3.78E+06 - - - 0.4086 - 1.091 0.264 - 113.9 1 2 0 0.0004 7 0 0 0 1.90E+08 2.20E+08 - - - 1.2668 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.11483.11483.2 0.00437 18-Nov K.YEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1178.5932 27.33 970 11483 2 1178.597424 590.3039 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2710.6 - 125276 - - - 3.6247 - 2.191 0.29 - 569 1 2 0 0.0043 10 0 0 0 2.58E+07 9.45E+05 - - - 3.371 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.11486.11486.2 0.00381 12-Jul K.MMVAGFK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 790.3961 0.87 971 11486 2 790.397154 396.2053 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2711 - 2.74E+06 - - - 1.331 - 1.413 0.451 - 251.1 1 2 0 0.0011 7 0 0 0 7.26E+09 8.30E+09 - - - 3.4672 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.11491.11491.2 0.0508 14-Oct K.IVGYVLAK[136.11].M "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN" 4 869.5466 1.42 974 11491 2 869.547242 435.7806 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 8.59 2711.7 - 2.63E+06 - - - 0.7498 - 1.565 0.293 - 240.3 1 2 0 0.0007 8 0 0 0 2.14E+08 1.51E+08 - - - 2.5557 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.11495.11495.2 0.000591 12-Jun K.MMVAGFK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 782.3819 0.88 976 11495 2 782.382452 392.1982 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2712.2 - 3.14E+06 - - - 0.703 - 1.54 0.46 - 159 1 2 0 0.0005 7 0 0 0 7.26E+09 8.30E+09 - - - 3.8065 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.11519.11519.2 0.367 14-Jul R.GLGGIMVK.R sp|O94776|MTA2_HUMAN 1 773.4469 1.38 983 11519 2 773.448114 387.7307 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 2715.6 - 1.05E+06 - - - 1.5101 - 1.18 0.284 - 130.7 1 2 0 0.0012 8 0 0 0 6.06E+07 4.39E+07 - - - 1.6374 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.11520.11520.3 9.87E-05 13/52 K.SQIHDIVLVGGSTR.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1480.7998 26.2 984 11520 3 1480.802153 494.6072 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2715.8 - 244428 - - - 1.5951 - 2.282 0.45 - 228.1 1 2 0 0.0024 14 0 0 0 1.92E+07 7.32E+05 - - - 5.749 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.11547.11547.2 0.018 14-Aug K.IYPSAYIK.V "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|A0A087WUF3|A0A087WUF3_HUMAN,tr|K7ELK2|K7ELK2_HUMAN" 4 953.5222 2.24 987 11547 2 953.523698 477.7684 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 8.5 2720.1 - 1.07E+06 - - - 1.5511 - 1.193 0.346 - 113.7 1 2 0 0.0015 8 0 0 0 6.57E+07 2.93E+07 - - - 2.1283 0.958 230117_WJC_METTL3_WT_vs_EV_F01.11551.11551.2 8.03 12-Oct K.LAPFIAK[136.11].R "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN,tr|K7ELX4|K7ELX4_HUMAN" 3 766.4833 1.77 988 11551 2 766.481946 384.2489 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 8.75 2720.7 - 3.18E+06 - - - -1.7156 - 1.354 0.063 - 245.9 1 2 0 -0.0013 7 0 0 0 5.33E+08 3.00E+08 - - - 0.4662 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.11576.11576.2 0.0655 16-Oct R.LLPAELPAK[136.11].R sp|P78527|PRKDC_HUMAN 1 958.5943 1.19 994 11576 2 958.595763 480.3044 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2724.4 - 616878 - - - 1.5596 - 1.609 0.276 - 270.4 1 2 0 0.0015 9 0 0 0 6.89E+07 5.80E+07 - - - 2.455 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.11596.11596.2 0.00482 16-Jul R.LLPAELPAK.R sp|P78527|PRKDC_HUMAN 1 950.5801 1.19 1004 11596 2 950.579275 476.2973 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2727 - 1.21E+06 - - - -0.8342 - 1.331 0.376 - 142.8 1 2 0 -0.0008 9 0 0 0 6.89E+07 5.80E+07 - - - 2.6451 0.9595 230117_WJC_METTL3_WT_vs_EV_F01.11605.11605.2 1.02 16-Aug N.LVIITAGAR.Q "sp|Q9BYZ2|LDH6B_HUMAN,sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 7 912.5757 0.97 1007 11605 2 912.576901 457.2951 L-lactate dehydrogenase A-like 6B OS=Homo sapiens OX=9606 GN=LDHAL6B PE=1 SV=3 9.75 2728.2 - 1.15E+06 - - - 1.3687 - 2.001 0.283 - 235.8 1 1 0 0.0012 9 0 0 0 2.24E+08 2.30E+08 - - - 3.1376 0.8609 230117_WJC_METTL3_WT_vs_EV_F01.11607.11607.2 0.182 16-Jul N.LVIITAGAR[166.11].Q "sp|Q9BYZ2|LDH6B_HUMAN,sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 7 922.5839 0.97 1008 11607 2 922.585804 462.2992 L-lactate dehydrogenase A-like 6B OS=Homo sapiens OX=9606 GN=LDHAL6B PE=1 SV=3 9.75 2728.4 - 1.70E+06 - - - 2.0399 - 1.606 0.208 - 116.3 2 1 0 0.0019 9 0 0 0 2.24E+08 2.30E+08 - - - 1.8128 0.9905 230117_WJC_METTL3_WT_vs_EV_F01.11628.11628.2 0.224 12-Jul R.FPGAYLK.G "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 794.4327 1.41 1015 11628 2 794.435117 398.2236 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.59 2731.4 - 1.06E+06 - - - 3.0726 - 1.424 0.111 - 121.8 1 2 0 0.0024 7 0 0 0 1.27E+08 9.05E+07 - - - 0.9801 0.9758 230117_WJC_METTL3_WT_vs_EV_F01.11632.11632.2 9.1 12-Jun K.IIDDLLK[136.11].N "sp|Q9H227|GBA3_HUMAN,tr|A0A087WTY7|A0A087WTY7_HUMAN" 2 836.5099 1.03 1018 11632 2 836.510869 419.2622 Cytosolic beta-glucosidase OS=Homo sapiens OX=9606 GN=GBA3 PE=1 SV=2 4.21 2731.7 - 1.66E+06 - - - 1.1942 - 1.249 0.047 - 79 3 2 0 0.001 7 0 0 0 8.71E+08 8.46E+08 - - - -0.1208 0.9754 230117_WJC_METTL3_WT_vs_EV_F01.11636.11636.2 0.999 14-Jul R.IGLETSLR[166.11].Y sp|Q9Y230|RUVB2_HUMAN 1 897.5159 1.67 1020 11636 2 897.512973 449.7652 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6 2732.2 - 299950 - - - -3.2635 - 1.545 0.173 - 95.6 1 2 0 -0.0029 8 0 0 0 5.42E+07 3.25E+07 - - - 1.6299 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.11639.11639.2 0.00853 12-Jul K.C[160.03]PVFVVR.W "sp|Q9C0J8|WDR33_HUMAN,tr|C9J8B4|C9J8B4_HUMAN" 2 875.4687 1.85 1022 11639 2 875.468019 438.7416 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 8.25 2732.5 - 500067 - - - -0.8281 - 1.491 0.356 - 138.7 1 2 0 -0.0007 7 0 0 0 1.24E+08 6.69E+07 - - - 2.9359 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.11651.11651.2 0.575 12-Aug R.IDGVLIR.M sp|O75663|TIPRL_HUMAN 1 784.4807 2.58 1025 11651 2 784.481513 393.2476 TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2 5.84 2734.3 - 1.50E+06 - - - 1.0504 - 1.484 0.131 - 150.4 1 2 0 0.0008 7 0 0 0 1.11E+08 4.30E+07 - - - 1.2591 0.9906 230117_WJC_METTL3_WT_vs_EV_F01.11656.11656.2 0.941 12-Aug R.VAGIFPR[166.11].L "sp|O96005|CLPT1_HUMAN,tr|K7EJ16|K7EJ16_HUMAN" 2 768.4522 0.86 1027 11656 2 768.452975 385.2334 Cleft lip and palate transmembrane protein 1 OS=Homo sapiens OX=9606 GN=CLPTM1 PE=1 SV=1 9.72 2734.9 - 817168 - - - 1.0358 - 1.334 0.078 - 220.7 1 2 0 0.0008 7 0 0 0 8.21E+07 9.56E+07 - - - 0.53 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.11659.11659.2 0.0408 14-Sep R.MVVPAALK[136.11].V "sp|P40429|RL13A_HUMAN,sp|Q6NVV1|R13P3_HUMAN,tr|M0QYS1|M0QYS1_HUMAN,tr|Q8J015|Q8J015_HUMAN,tr|A0A7I2V2L9|A0A7I2V2L9_HUMAN,tr|A0A7I2V5L3|A0A7I2V5L3_HUMAN" 6 835.5081 0.82 1028 11659 2 835.508817 418.7613 60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2 8.5 2735.3 - 1.05E+07 - - - 0.8629 - 1.652 0.269 - 326 1 2 0 0.0007 8 0 0 0 1.28E+09 1.57E+09 - - - 2.5416 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.11664.11664.2 0.416 14-Jul K.LINAVELK.K sp|P56192|SYMC_HUMAN 1 898.5488 1.1 1031 11664 2 898.549966 450.2817 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6 2735.9 - 1.28E+06 - - - 1.3333 - 1.266 0.208 - 87.2 1 2 0 0.0012 8 0 0 0 2.68E+08 2.44E+08 - - - 1.2883 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.11667.11667.2 0.132 14-Aug K.LINAVELK[136.11].K sp|P56192|SYMC_HUMAN 1 906.563 1.09 1032 11667 2 906.564196 454.2888 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6 2736.3 - 1.72E+06 - - - 1.3546 - 1.645 0.286 - 144.4 1 2 0 0.0012 8 0 0 0 2.68E+08 2.46E+08 - - - 2.6542 0.9646 230117_WJC_METTL3_WT_vs_EV_F01.11700.11700.2 12.1 12-Jun R.FPGAYLK[136.11].G "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 802.4469 1.4 1042 11700 2 802.447771 402.2307 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.59 2740.9 - 811706 - - - 1.1153 - 1.056 0.075 - 99.4 2 2 0 0.0009 7 0 0 0 1.31E+08 9.37E+07 - - - -0.3672 0.998 230117_WJC_METTL3_WT_vs_EV_F01.11702.11702.2 0.000768 14-Aug R.FGPLASVK.L "sp|O15042|SR140_HUMAN,tr|E7EW00|E7EW00_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H0Y8D9|H0Y8D9_HUMAN" 4 817.4698 0.15 1043 11702 2 817.470735 409.7422 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 8.75 2741.1 - 1.46E+06 - - - 1.156 - 1.718 0.142 - 180.9 1 2 0 0.0009 8 0 0 0 1.67E+08 1.14E+09 - - - 1.7216 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.11706.11706.2 0.00599 14-Sep R.MVLVGDVK.D "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PEU0|A0A6Q8PEU0_HUMAN,tr|A0A6Q8PHI4|A0A6Q8PHI4_HUMAN,tr|A0A6Q8PG82|A0A6Q8PG82_HUMAN" 7 859.4837 2.04 1045 11706 2 859.484745 430.7491 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 5.59 2741.5 - 2.66E+06 - - - 1.1868 - 1.536 0.35 - 336.8 1 2 0 0.001 8 0 0 0 2.89E+08 1.42E+08 - - - 2.9202 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.11709.11709.2 1.02 12-Jul K.LLQEIVR.S "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 869.5335 1.44 1047 11709 2 869.533652 435.774 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6 2741.9 - 1.52E+06 - - - 0.23 - 1.415 0.274 - 163.6 1 2 0 0.0002 7 0 0 0 9.58E+07 6.66E+07 - - - 2.1646 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.11711.11711.2 0.0462 14-Sep R.MVLVGDVK[136.11].D "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PEU0|A0A6Q8PEU0_HUMAN,tr|A0A6Q8PHI4|A0A6Q8PHI4_HUMAN,tr|A0A6Q8PG82|A0A6Q8PG82_HUMAN" 7 867.4979 2.04 1048 11711 2 867.497917 434.7562 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 5.59 2742.1 - 1.66E+06 - - - -0.0092 - 1.738 0.335 - 321.3 1 2 0 0 8 0 0 0 2.89E+08 1.41E+08 - - - 3.1823 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.11720.11720.2 0.0023 20-Aug K.VLFSSNGGVVK[136.11].G "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 1113.6274 1.22 1051 11720 2 1113.628724 557.821 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.72 2743.3 - 261440 - - - 1.2257 - 1.582 0.344 - 124.2 1 2 0 0.0014 11 0 0 0 1.40E+07 1.14E+07 - - - 2.8222 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.11725.11725.2 0.753 14-Jul R.LVSLIGSK.T "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 815.5117 1.95 1053 11725 2 815.512806 408.7631 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 2744 - 1.38E+06 - - - 1.4126 - 1.272 0.15 - 113.4 1 2 0 0.0012 8 0 0 0 1.01E+08 5.18E+07 - - - 0.8741 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.11731.11731.2 0.00808 16-Oct K.NDLAVVDVR[166.11].L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1009.5432 0.72 1056 11731 2 1009.545843 505.7789 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.21 2744.8 - 539583 - - - 2.6388 - 1.979 0.419 - 481.8 1 2 0 0.0027 9 0 0 0 1.73E+07 2.39E+07 - - - 4.1097 0.9932 230117_WJC_METTL3_WT_vs_EV_F01.11733.11733.2 0.583 12-Jul R.VAGIFPR.L "sp|O96005|CLPT1_HUMAN,tr|K7EJ16|K7EJ16_HUMAN" 2 758.4439 0.85 1057 11733 2 758.445551 380.2292 Cleft lip and palate transmembrane protein 1 OS=Homo sapiens OX=9606 GN=CLPTM1 PE=1 SV=1 9.72 2745 - 841563 - - - 2.165 - 1.305 0.133 - 152.1 1 2 0 0.0016 7 0 0 0 8.21E+07 9.61E+07 - - - 0.8663 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.11735.11735.2 0.0738 14-Jul R.LLGQIVDR.C sp|Q96I24|FUBP3_HUMAN 1 912.5393 1.49 1058 11735 2 912.541939 457.2769 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2745.2 - 1.09E+07 - - - 2.9292 - 1.443 0.218 - 86.5 1 2 0 0.0027 8 0 0 0 1.50E+09 1.01E+09 - - - 1.7563 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.11737.11737.2 0.582 12-Jul R.NLVVIPK[136.11].S sp|P15121|ALDR_HUMAN 1 789.5204 1.02 1059 11737 2 789.522284 395.7675 Aldo-keto reductase family 1 member B1 OS=Homo sapiens OX=9606 GN=AKR1B1 PE=1 SV=3 8.75 2745.5 - 343226 - - - 2.4179 - 1.325 0.187 - 112.2 1 2 0 0.0019 7 0 0 0 5.06E+07 4.96E+07 - - - 1.3133 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.11739.11739.2 0.271 14-Sep R.LLGQIVDR[166.11].C sp|Q96I24|FUBP3_HUMAN 1 922.5475 1.49 1060 11739 2 922.54891 462.281 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2745.7 - 6.75E+06 - - - 1.4894 - 1.756 0.18 - 263.6 1 2 0 0.0014 8 0 0 0 1.50E+09 1.01E+09 - - - 2.0681 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.11740.11740.2 0.163 14-Jul K.MVSAAFMK.K "sp|P25205|MCM3_HUMAN,tr|Q7Z6P5|Q7Z6P5_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 4 883.4296 2.94 1061 11740 2 883.430822 442.7221 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 8.5 2745.8 - 1.61E+06 - - - 1.4048 - 1.414 0.209 - 170.1 1 2 0 0.0012 8 0 0 0 6.33E+07 2.15E+07 - - - 1.6291 1 230117_WJC_METTL3_WT_vs_EV_F01.11744.11744.3 1.70E-10 21/84 K.DHTPSQELALTQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2270.0411 121.22 1062 11744 3 2270.045709 757.6876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2746.3 - 313845 - - - 2.0317 - 3.787 0.635 - 282.3 1 2 0 0.0046 22 0 0 0 7.12E+06 5.87E+04 - - - 8.7753 1 230117_WJC_METTL3_WT_vs_EV_F01.11756.11756.2 6.01E-11 Oct-32 N.IVSNASC[160.03]TTNC[160.03]LAPLAK.V "sp|O14556|G3PT_HUMAN,tr|K7EP73|K7EP73_HUMAN" 2 1818.8968 999 1067 11756 2 1818.90145 910.4557 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 8.06 2747.8 - 111401 - - - 2.5537 - 2.625 0.665 - 173.4 1 1 0 0.0046 17 0 0 0 6.72E+06 0.00E+00 - - - 6.3239 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.11762.11762.2 0.0671 14-Oct R.LGMGLVSR.S "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 831.4637 1.3 1071 11762 2 831.465044 416.7391 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 9.75 2748.4 - 1.78E+06 - - - 1.6669 - 2.369 0.313 - 319 1 2 0 0.0014 8 0 0 0 7.95E+07 6.12E+07 - - - 3.9535 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.11769.11769.2 0.0649 12-Jul K.YVMVVYK.R "sp|Q9BPX3|CND3_HUMAN,tr|D6RA93|D6RA93_HUMAN" 2 900.4779 1.75 1076 11769 2 900.480273 451.2462 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 8.5 2749.3 - 614553 - - - 2.6231 - 1.225 0.297 - 147.8 1 2 0 0.0024 7 0 0 0 2.77E+07 1.58E+07 - - - 1.8769 1 230117_WJC_METTL3_WT_vs_EV_F01.11789.11789.3 9.46E-08 Oct-68 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 2.3 1085 11789 3 2070.877714 691.296 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2752 - 103640 - - - 5.5156 - 2.303 0.663 - 55.1 1 2 0 0.0114 18 0 0 0 1.27E+07 5.52E+06 - - - 8.0059 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.11797.11797.2 0.000163 18-Sep K.FGEVVDC[160.03]TIK.M "sp|Q99729|ROAA_HUMAN,sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 13 1166.5642 0.31 1088 11797 2 1166.566552 584.2894 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 4.37 2753 - 118917 - - - 2.0496 - 1.832 0.407 - 248.8 1 2 0 0.0024 10 0 0 0 3.54E+06 1.13E+07 - - - 3.7362 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.11803.11803.2 0.0389 18-Jul K.LITPAVVSER[166.11].L sp|P62851|RS25_HUMAN 1 1093.6371 1.08 1089 11803 2 1093.63907 547.8258 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 6 2754 - 83439.3 - - - 1.8205 - 1.491 0.199 - 126.2 1 2 0 0.002 10 0 0 0 1.43E+07 1.33E+07 - - - 1.6252 0.9937 230117_WJC_METTL3_WT_vs_EV_F01.11809.11809.2 0.257 12-Jun R.SIFDHIK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 866.4742 0.82 1092 11809 2 866.475694 434.2444 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.46 2754.7 - 979292 - - - 1.7785 - 0.937 0.271 - 98.6 1 2 0 0.0015 7 0 0 0 5.01E+07 6.08E+07 - - - 0.8359 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.11821.11821.2 0.372 16-Oct K.VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 919.5946 2.03 1097 11821 2 919.595845 460.8046 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2756.3 - 1.69E+06 - - - 1.3506 - 1.719 0.255 - 214 1 2 0 0.0012 9 0 0 0 8.28E+08 4.07E+08 - - - 2.4913 0.9956 230117_WJC_METTL3_WT_vs_EV_F01.11822.11822.2 0.049 12-Aug R.VFVVMEK.L "sp|Q15139|KPCD1_HUMAN,sp|O94806|KPCD3_HUMAN,sp|Q9BZL6|KPCD2_HUMAN,tr|M0R2Z8|M0R2Z8_HUMAN,tr|F8WBA3|F8WBA3_HUMAN" 5 850.4623 0.14 1098 11822 2 850.460873 426.2384 Serine\threonine-protein kinase D1 OS=Homo sapiens OX=9606 GN=PRKD1 PE=1 SV=2 5.97 2756.4 - 158306 - - - -1.6321 - 1.59 0.242 - 151.1 1 2 0 -0.0014 7 0 0 0 1.75E+07 1.28E+08 - - - 2.2973 0.9692 230117_WJC_METTL3_WT_vs_EV_F01.11823.11823.2 1.95 12-May K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 2.91 1099 11823 2 828.474022 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2756.6 - 410025 - - - 0.8618 - 1.301 0.038 - 54.9 8 2 0 0.0007 7 0 0 0 4.33E+07 1.49E+07 - - - -0.2482 1 230117_WJC_METTL3_WT_vs_EV_F01.11828.11828.3 1.14E-05 15/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 2.3 1102 11828 3 2079.882592 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2757.2 - 126984 - - - 482.0383 - 2.698 0.617 - 198.2 1 2 0 1.0021 18 0 0 0 1.27E+07 5.52E+06 - - - 7.6128 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.11829.11829.2 2.29 16-Apr K.SC[160.03]AHDWVYE.- "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 3 1165.4499 - 1103 11829 2 1165.452841 583.7322 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 4.71 2757.4 - 77096 - - - 2.5587 - 0.88 0.377 - 43.6 1 2 0 0.003 9 0 0 0 - - - - - 1.4548 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.11832.11832.2 0.799 16-Nov K.VGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 911.5804 2.04 1104 11832 2 911.582358 456.7975 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2757.8 - 6.36E+06 - - - 2.1446 - 2.171 0.285 - 337.8 1 2 0 0.002 9 0 0 0 8.29E+08 4.07E+08 - - - 3.3881 0.9236 230117_WJC_METTL3_WT_vs_EV_F01.11835.11835.2 2.18 12-Jun R.ALLC[160.03]TLR.A "sp|P23434|GCSH_HUMAN,tr|H3BUG8|H3BUG8_HUMAN,tr|A0A1W2PS29|A0A1W2PS29_HUMAN,tr|A0A1W2PQX3|A0A1W2PQX3_HUMAN,tr|H3BPF0|H3BPF0_HUMAN,tr|H3BUH9|H3BUH9_HUMAN,tr|A0A1W2PQF2|A0A1W2PQF2_HUMAN,tr|A0A1W2PRH4|A0A1W2PRH4_HUMAN,tr|A0A1W2PPQ1|A0A1W2PPQ1_HUMAN,tr|A0A1W2PNX3|A0A1W2PNX3_HUMAN" 10 845.4793 0.35 1107 11835 2 845.483672 423.7469 "Glycine cleavage system H protein, mitochondrial OS=Homo sapiens OX=9606 GN=GCSH PE=1 SV=2" 8.29 2758.1 - 794425 - - - 5.1604 - 1.152 0.158 - 97.6 3 2 0 0.0044 7 0 0 0 9.24E+06 2.65E+07 - - - 0.4418 0.9504 230117_WJC_METTL3_WT_vs_EV_F01.11838.11838.2 0.0238 12-Jul K.VEPVYLR.G sp|Q8NDT2|RB15B_HUMAN 1 874.4913 0.92 1108 11838 2 874.493651 438.2529 Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3 5.97 2758.5 - 1.05E+06 - - - 2.7422 - 1.273 0.003 - 210.6 2 2 0 0.0024 7 0 0 0 1.52E+08 1.65E+08 - - - -0.3073 0.9946 230117_WJC_METTL3_WT_vs_EV_F01.11859.11859.2 0.0109 12-Jun K.LDPVLYR[166.11].K "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 884.4995 0.92 1118 11859 2 884.501527 443.257 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 5.84 2761.3 - 3.09E+06 - - - 2.2657 - 1.239 0.184 - 181.8 1 2 0 0.002 7 0 0 0 1.51E+08 1.65E+08 - - - 1.0784 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.11868.11868.3 0.0575 15/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 0.77 1122 11868 3 1166.703468 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2762.5 - 1.80E+06 - - - 0.9934 - 2.442 0.256 - 188.8 1 2 0 0.0012 11 0 0 0 3.63E+08 4.73E+08 - - - 3.9302 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.11873.11873.2 0.00114 18-Aug K.YEELQVTVGR.H sp|P35908|K22E_HUMAN 1 1192.6088 20.39 1124 11873 2 1192.612577 597.3117 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.53 2763.1 - 133100 - - - 3.1653 - 1.532 0.372 - 225.8 1 2 0 0.0038 10 0 0 0 2.91E+06 1.43E+05 - - - 2.9781 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.11886.11886.2 1.49 12-Jul R.LGLTEIR[166.11].K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 810.4839 1.18 1127 11886 2 810.484709 406.2492 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2765.1 - 1.92E+06 - - - 1.0315 - 1.619 0.151 - 155.5 1 2 0 0.0008 7 0 0 0 1.20E+09 1.02E+09 - - - 1.6827 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.11890.11890.2 0.398 12-Sep K.LEDLIVK[136.11].D "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 836.5099 1.98 1129 11890 2 836.510466 419.2622 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2765.6 - 1.41E+07 - - - 0.7125 - 2.035 0.121 - 279.6 1 2 0 0.0006 7 0 0 0 1.64E+09 8.28E+08 - - - 2.1858 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.11894.11894.2 0.173 12-Sep K.LEDLIVK.D "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 828.4957 1.98 1132 11894 2 828.496565 415.2551 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2766 - 2.36E+07 - - - 1.0803 - 2.027 0.121 - 283.4 1 2 0 0.0009 7 0 0 0 1.64E+09 8.28E+08 - - - 2.1732 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.11897.11897.3 0.00064 13/40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 0.77 1133 11897 3 1174.71807 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2766.4 - 1.26E+07 - - - 1.3288 - 2.525 0.224 - 148.3 1 2 0 0.0016 11 0 0 0 3.63E+08 4.73E+08 - - - 3.6682 0.991 230117_WJC_METTL3_WT_vs_EV_F01.11901.11901.2 3.45 12-Jun K.FLEATLR.S "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN" 2 848.4756 0.84 1137 11901 2 848.4748 425.2451 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 6 2766.8 - 530964 - - - -0.9464 - 1.375 0.164 - 119 1 2 0 -0.0008 7 0 0 0 4.38E+07 5.20E+07 - - - 1.2611 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.11904.11904.2 1.88 12-Jul R.LGLTEIR.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 800.4756 1.18 1138 11904 2 800.476206 401.2451 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2767.2 - 6.12E+06 - - - 0.7533 - 1.67 0.131 - 175.3 1 2 0 0.0006 7 0 0 0 1.20E+09 1.02E+09 - - - 1.6333 0.9566 230117_WJC_METTL3_WT_vs_EV_F01.11907.11907.2 0.0273 18-Nov L.LASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1053.6182 0.71 1139 11907 2 1053.618661 527.8164 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2767.6 - 423674 - - - 0.3948 - 2.094 0.3 - 356.1 1 1 0 0.0004 10 0 0 0 1.32E+07 1.86E+07 - - - 3.3197 0.8792 230117_WJC_METTL3_WT_vs_EV_F01.11927.11927.2 5.54 12-May K.LLSTFPR[166.11].R "sp|Q9UNN5|FAF1_HUMAN,tr|B3KT28|B3KT28_HUMAN,tr|B1ANM7|B1ANM7_HUMAN" 3 842.489 1.81 1145 11927 2 842.488827 422.2518 FAS-associated factor 1 OS=Homo sapiens OX=9606 GN=FAF1 PE=1 SV=2 9.75 2770.5 - 456184 - - - -0.1567 - 1.034 0.072 - 42.4 19 2 0 -0.0001 7 0 0 0 1.81E+08 9.96E+07 - - - -0.8925 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.11939.11939.2 0.0582 14-Aug K.LIEQYALR.E sp|Q9NUQ3|TXLNG_HUMAN 1 1004.5655 1.56 1150 11939 2 1004.565607 503.29 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2772.2 - 313754 - - - 0.1254 - 1.467 0.187 - 187.1 1 2 0 0.0001 8 0 0 0 4.53E+07 2.90E+07 - - - 1.5779 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.11946.11946.2 0.467 14-Aug K.LIEQYALR[166.11].E sp|Q9NUQ3|TXLNG_HUMAN 1 1014.5738 1.56 1153 11946 2 1014.577084 508.2942 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2773.1 - 276681 - - - 3.2851 - 1.505 0.164 - 187.2 1 2 0 0.0033 8 0 0 0 4.53E+07 2.90E+07 - - - 1.4842 0.9795 230117_WJC_METTL3_WT_vs_EV_F01.11956.11956.2 0.225 12-May K.LMPTQWR.T sp|Q99459|CDC5L_HUMAN 1 930.4746 1.17 1156 11956 2 930.474775 466.2446 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.75 2774.5 - 368562 - - - 0.2343 - 1.037 0.165 - 86.8 3 2 0 0.0002 7 0 0 0 5.12E+07 4.38E+07 - - - 0.1616 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.11965.11965.2 0.0898 12-Jul R.IGNFIVK.K "sp|Q00796|DHSO_HUMAN,tr|H0YKB3|H0YKB3_HUMAN,tr|A0A6I8PIS1|A0A6I8PIS1_HUMAN" 3 789.4749 38.84 1160 11965 2 789.476255 395.7447 Sorbitol dehydrogenase OS=Homo sapiens OX=9606 GN=SORD PE=1 SV=4 8.75 2775.8 - 779367 - - - 1.748 - 1.288 0.192 - 100.4 1 2 0 0.0014 7 0 0 0 3.67E+07 9.44E+05 - - - 1.2606 0.984 230117_WJC_METTL3_WT_vs_EV_F01.11966.11966.2 1.16 12-Jun K.LMPTQWR[166.11].T sp|Q99459|CDC5L_HUMAN 1 940.4828 1.16 1161 11966 2 940.484243 471.2487 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.75 2775.9 - 976098 - - - 1.5056 - 1.138 0.095 - 158.4 1 2 0 0.0014 7 0 0 0 5.08E+07 4.37E+07 - - - 0.1518 0.9935 230117_WJC_METTL3_WT_vs_EV_F01.11969.11969.2 0.149 14-Aug R.VLDALVAR.E sp|Q8IUR0|TPPC5_HUMAN 1 855.5178 2.2 1162 11969 2 855.519318 428.7662 Trafficking protein particle complex subunit 5 OS=Homo sapiens OX=9606 GN=TRAPPC5 PE=1 SV=1 5.81 2776.2 - 925307 - - - 1.772 - 1.358 0.115 - 166.9 1 2 0 0.0015 8 0 0 0 5.38E+07 2.45E+07 - - - 0.8128 0.974 230117_WJC_METTL3_WT_vs_EV_F01.11980.11980.2 2.05 12-Jun R.GSLHVWK.S "sp|O97980|HMHB1_HUMAN,tr|A0A1X7SBT3|A0A1X7SBT3_HUMAN" 2 825.4497 10.41 1168 11980 2 825.450405 413.7321 Minor histocompatibility protein HB-1 OS=Homo sapiens OX=9606 GN=HMHB1 PE=1 SV=1 8.76 2777.5 - 3.47E+06 - - - 0.8262 - 1.123 0.091 - 127.2 3 2 0 0.0007 7 0 0 0 1.57E+08 1.51E+07 - - - -0.1327 0.9969 230117_WJC_METTL3_WT_vs_EV_F01.11992.11992.2 0.234 14-Jul K.VPYLAVAR[166.11].T "sp|P18858|DNLI1_HUMAN,tr|F5GZ28|F5GZ28_HUMAN,tr|M0R0Q7|M0R0Q7_HUMAN,tr|B4E135|B4E135_HUMAN" 4 897.5312 1.81 1173 11992 2 897.532792 449.7729 DNA ligase 1 OS=Homo sapiens OX=9606 GN=LIG1 PE=1 SV=1 8.72 2779.2 - 521618 - - - 1.8205 - 1.276 0.22 - 103.8 1 2 0 0.0016 8 0 0 0 3.30E+07 1.83E+07 - - - 1.4005 0.9888 230117_WJC_METTL3_WT_vs_EV_F01.11994.11994.2 0.756 16-Jun R.LITGLGVGR[166.11].E sp|Q9BQG0|MBB1A_HUMAN 1 894.5526 1.19 1174 11994 2 894.555137 448.2836 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 9.75 2779.4 - 424680 - - - 2.8126 - 1.263 0.157 - 68.8 2 2 0 0.0025 9 0 0 0 1.84E+08 1.54E+08 - - - 0.7408 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.12017.12017.2 0.0132 13/24 R.GGIGAGLGGGLC[160.03]R[166.11].R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1153.5901 0.6 1182 12017 2 1153.592202 577.8023 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2782.6 - 441163 - - - 1.7823 - 2.029 0.367 - 378.9 1 2 0 0.0021 13 0 0 0 1.28E+07 2.15E+07 - - - 3.5669 0.97 230117_WJC_METTL3_WT_vs_EV_F01.12018.12018.2 0.0721 24-Jul R.GGIGAGLGGGLC[160.03]R.R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1143.5819 0.62 1183 12018 2 1143.581457 572.7982 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2782.7 - 222375 - - - -0.3664 - 1.377 0.064 - 75.3 3 2 0 -0.0004 13 0 0 0 1.32E+07 2.15E+07 - - - 0.1215 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.12030.12030.2 0.0134 14-Aug K.ILVDALQK[136.11].F "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 15 906.563 1.04 1188 12030 2 906.561739 454.2888 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 5.84 2784.5 - 400776 - - - -1.3557 - 1.534 0.21 - 137.9 1 2 0 -0.0012 8 0 0 0 7.69E+07 7.38E+07 - - - 1.8821 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.12034.12034.2 1.03E-05 20-Nov K.LATNAAVTVLR.V "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1127.6663 999 1189 12034 2 1127.667251 564.8404 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 9.75 2785 - 292204 - - - 0.8806 - 2.134 0.366 - 359.6 1 2 0 0.001 11 0 0 0 9.63E+06 0.00E+00 - - - 3.7945 0.9497 230117_WJC_METTL3_WT_vs_EV_F01.12036.12036.2 0.763 12-Jul K.FVNLYTR[166.11].E "sp|Q15650|TRIP4_HUMAN,tr|H0YL91|H0YL91_HUMAN" 2 921.4948 1.84 1190 12036 2 921.495513 461.7547 Activating signal cointegrator 1 OS=Homo sapiens OX=9606 GN=TRIP4 PE=1 SV=4 8.75 2785.3 - 504760 - - - 0.8041 - 1.167 0.006 - 130.5 2 2 0 0.0007 7 0 0 0 3.00E+07 1.64E+07 - - - -0.56 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.12038.12038.2 0.00262 14-Aug K.ILVDALQK.F "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 15 898.5488 1.03 1192 12038 2 898.550134 450.2817 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 5.84 2785.5 - 768504 - - - 1.5202 - 1.667 0.298 - 146.3 1 2 0 0.0014 8 0 0 0 7.38E+07 7.18E+07 - - - 2.7828 0.9929 230117_WJC_METTL3_WT_vs_EV_F01.12044.12044.2 0.012 12-Jul R.AAYIYIR[166.11].G "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|B4DE93|B4DE93_HUMAN,tr|E9PJL9|E9PJL9_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PLC6|E9PLC6_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN" 8 878.489 3.73 1194 12044 2 878.487283 440.2518 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.63 2786.3 - 247873 - - - -1.9078 - 1.481 0.232 - 163.7 1 2 0 -0.0017 7 0 0 0 1.07E+08 2.88E+07 - - - 1.9984 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.12072.12072.2 0.485 14-Aug R.ALLGPALK.D sp|P35250|RFC2_HUMAN 1 781.5062 1.9 1206 12072 2 781.506221 391.7604 Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3 8.8 2789.9 - 2.81E+06 - - - 0.0589 - 1.495 0.253 - 214.5 1 2 0 0 8 0 0 0 1.21E+08 6.41E+07 - - - 2.1224 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.12089.12089.2 0.315 12-Sep K.LTELLVK[136.11].A "sp|O95470|SGPL1_HUMAN,tr|H0Y3V8|H0Y3V8_HUMAN,tr|H7BXL7|H7BXL7_HUMAN" 3 822.5306 2.24 1214 12089 2 822.533468 412.2726 Sphingosine-1-phosphate lyase 1 OS=Homo sapiens OX=9606 GN=SGPL1 PE=1 SV=3 6 2792.1 - 918117 - - - 3.4807 - 1.956 0.28 - 217 1 2 0 0.0029 7 0 0 0 7.27E+07 3.24E+07 - - - 3.234 1 230117_WJC_METTL3_WT_vs_EV_F01.12095.12095.2 0.000123 17/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 17293.73 1218 12095 2 1302.609423 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2792.7 - 934956 - - - 0.1743 - 2.575 0.557 - 623.9 1 2 0 0.0002 13 0 0 0 2.04E+09 1.18E+05 - - - 5.5825 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.12100.12100.2 0.102 12-Jul K.VPVNLLR[166.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 819.5206 1.17 1221 12100 2 819.52068 410.7676 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2793.2 - 1.84E+06 - - - 0.1062 - 1.336 0.274 - 281.9 1 2 0 0.0001 7 0 0 0 1.85E+08 1.58E+08 - - - 1.9826 0.9936 230117_WJC_METTL3_WT_vs_EV_F01.12105.12105.2 0.05 12-Jun K.VPVNLLR.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 809.5123 1.17 1224 12105 2 809.51181 405.7634 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2793.9 - 2.47E+06 - - - -0.6337 - 1.171 0.249 - 159.4 1 2 0 -0.0005 7 0 0 0 1.85E+08 1.58E+08 - - - 1.3801 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.12107.12107.2 6.21E-06 20-Oct R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 4888.88 1225 12107 2 1201.608326 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2794.1 - 1.14E+06 - - - -0.6749 - 2.019 0.458 - 129.8 1 2 0 -0.0008 11 0 0 0 8.67E+09 1.77E+06 - - - 4.3242 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.12111.12111.2 0.406 12-Aug K.IDPLLPK.E sp|Q9BYD6|RM01_HUMAN 1 794.4902 2.76 1228 12111 2 794.489757 398.2524 "39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2" 5.84 2794.4 - 2.73E+06 - - - -0.5463 - 1.519 0.212 - 195.6 1 2 0 -0.0004 7 0 0 0 3.33E+08 1.21E+08 - - - 1.9313 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.12129.12129.2 0.0018 12-Sep R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 2.11 1233 12129 2 852.483536 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2796.9 - 1.82E+07 - - - -0.1396 - 1.636 0.385 - 240.7 1 2 0 -0.0001 7 0 0 0 1.94E+09 9.21E+08 - - - 3.4443 0.9333 230117_WJC_METTL3_WT_vs_EV_F01.12141.12141.2 0.0363 14-Sep R.LLASTLVH.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 852.5069 - 1238 12141 2 852.506605 427.2607 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.74 2798.4 - 1.53E+07 - - - -0.3496 - 1.576 0.381 - 221.5 1 1 0 -0.0003 8 0 0 0 - - - - - 3.2269 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.12149.12149.3 0.384 Dec-40 R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 814.91 1243 12149 3 1201.60907 401.5437 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2799.3 - 2.55E+06 - - - -0.0558 - 1.945 0.232 - 184.4 1 2 0 -0.0001 11 0 0 0 5.60E+08 6.87E+05 - - - 3.0164 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.12153.12153.2 0.201 14-Jul K.ILFTEATR.L "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 949.5233 1.98 1245 12153 2 949.524073 475.7689 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 6 2799.8 - 1.02E+06 - - - 0.833 - 1.46 0.319 - 140.1 1 2 0 0.0008 8 0 0 0 5.97E+07 3.02E+07 - - - 2.5382 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.12159.12159.2 0.0268 12-Aug R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.34 1249 12159 2 844.469555 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2800.6 - 2.87E+07 - - - 0.1184 - 1.539 0.263 - 201 1 2 0 0.0001 7 0 0 0 1.36E+10 1.02E+10 - - - 2.3496 0.96 230117_WJC_METTL3_WT_vs_EV_F01.12162.12162.2 0.0688 22-Jun K.FEDVGGNDMTLK.E "sp|O15381|NVL_HUMAN,tr|C9J6P7|C9J6P7_HUMAN,tr|E7EWK7|E7EWK7_HUMAN,tr|C9JP83|C9JP83_HUMAN" 4 1324.5969 70.11 1250 12162 2 1324.594618 663.3057 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 4.03 2801 - 251166 - - - -1.7356 - 1.441 0.087 - 80.4 2 2 0 -0.0023 12 0 0 0 6.89E+06 9.82E+04 - - - 0.5097 0.9366 230117_WJC_METTL3_WT_vs_EV_F01.12182.12182.2 0.163 12-Jun K.GLVLMSR[166.11].A "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 16 784.4505 1.07 1256 12182 2 784.450171 393.2325 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 9.75 2803.7 - 6.47E+06 - - - -0.3748 - 1.254 0 - 154.7 2 2 0 -0.0003 7 0 0 0 6.37E+08 5.97E+08 - - - -0.3764 0.9876 230117_WJC_METTL3_WT_vs_EV_F01.12187.12187.2 0.216 12-Jul K.MLEYALK.Q "sp|Q13033|STRN3_HUMAN,sp|Q9NRL3|STRN4_HUMAN,sp|O43815|STRN_HUMAN,tr|M0R0P4|M0R0P4_HUMAN,tr|G3V3G7|G3V3G7_HUMAN,tr|F5GYK2|F5GYK2_HUMAN,tr|M0R2A7|M0R2A7_HUMAN,tr|M0QYS2|M0QYS2_HUMAN,tr|M0R0W8|M0R0W8_HUMAN,tr|G3V340|G3V340_HUMAN,tr|M0QXN2|M0QXN2_HUMAN" 11 866.4572 3.92 1258 12187 2 866.455166 434.2359 Striatin-3 OS=Homo sapiens OX=9606 GN=STRN3 PE=1 SV=3 5.75 2804.3 - 1.03E+06 - - - -2.3198 - 1.224 0.277 - 175.8 1 2 0 -0.002 7 0 0 0 6.47E+07 1.65E+07 - - - 1.7267 0.9901 230117_WJC_METTL3_WT_vs_EV_F01.12188.12188.2 0.302 14-Aug R.LLEEGVLR.Q "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 927.5389 2.13 1259 12188 2 927.536458 464.7767 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 2804.4 - 296217 - - - -2.6673 - 1.394 0.284 - 177.7 1 2 0 -0.0025 8 0 0 0 1.66E+08 7.81E+07 - - - 2.1397 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.12191.12191.2 0.0462 14-Aug R.VFVSPLAK[136.11].K "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 867.5309 0.79 1260 12191 2 867.530113 434.7727 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 8.72 2804.8 - 1.68E+06 - - - -0.9533 - 1.547 0.264 - 250.5 1 2 0 -0.0008 8 0 0 0 4.21E+08 5.30E+08 - - - 2.3066 0.9763 230117_WJC_METTL3_WT_vs_EV_F01.12192.12192.2 3.46 12-Aug K.IPVIIER.Y "sp|A6NCE7|MP3B2_HUMAN,sp|Q9GZQ8|MLP3B_HUMAN,sp|Q9H492|MLP3A_HUMAN,tr|H3BTL1|H3BTL1_HUMAN" 4 838.5276 1.26 1261 12192 2 838.526387 420.2711 Microtubule-associated proteins 1A\1B light chain 3 beta 2 OS=Homo sapiens OX=9606 GN=MAP1LC3B2 PE=2 SV=1 6 2805 - 1.06E+06 - - - -1.4931 - 1.468 0.071 - 253.1 1 2 0 -0.0013 7 0 0 0 6.09E+07 4.82E+07 - - - 0.7814 0.9406 230117_WJC_METTL3_WT_vs_EV_F01.12205.12205.2 2.41 12-Jun R.ILLYAC[160.03]R.N "sp|P36954|RPB9_HUMAN,tr|K7EKS1|K7EKS1_HUMAN" 2 907.495 1.38 1267 12205 2 907.493426 454.7548 DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1 8.22 2806.5 - 211905 - - - -1.6893 - 1.166 0.092 - 116.1 1 2 0 -0.0015 7 0 0 0 1.21E+08 8.74E+07 - - - 0.2067 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.12207.12207.2 0.00644 16-Sep K.LVPVGYGIK.K sp|P24534|EF1B_HUMAN 1 944.5695 0.73 1268 12207 2 944.568782 473.292 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2806.7 - 7.52E+06 - - - -0.7644 - 1.733 0.313 - 360 1 2 0 -0.0007 9 0 0 0 1.64E+09 2.24E+09 - - - 2.9433 0.9945 230117_WJC_METTL3_WT_vs_EV_F01.12222.12222.2 0.545 14-Jun R.VFVSPLAK.K "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 859.5167 0.79 1270 12222 2 859.517332 430.7656 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 8.72 2809.1 - 5.98E+06 - - - 0.6888 - 1.207 0.185 - 103.5 1 2 0 0.0006 8 0 0 0 4.21E+08 5.30E+08 - - - 0.9746 0.9487 230117_WJC_METTL3_WT_vs_EV_F01.12223.12223.2 3.49 12-Jul R.YISGILR.K "sp|P46020|KPB1_HUMAN,sp|P46019|KPB2_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 4 820.4807 1.5 1271 12223 2 820.47991 411.2476 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 8.75 2809.2 - 1.06E+06 - - - -0.9494 - 1.243 0.036 - 138.2 1 2 0 -0.0008 7 0 0 0 9.54E+07 6.38E+07 - - - -0.0041 0.9613 230117_WJC_METTL3_WT_vs_EV_F01.12228.12228.2 0.0683 16-Sep R.NVIEAVYSR[166.11].L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1059.5588 1.48 1273 12228 2 1059.554501 530.7867 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 2809.9 - 1.23E+06 - - - -4.0847 - 1.352 0.238 - 293.6 1 2 0 -0.0043 9 0 0 0 8.98E+07 6.09E+07 - - - 1.67 0.9584 230117_WJC_METTL3_WT_vs_EV_F01.12239.12239.2 0.402 12-Aug R.ILLYAC[160.03]R[166.11].N "sp|P36954|RPB9_HUMAN,tr|K7EKS1|K7EKS1_HUMAN" 2 917.5032 1.38 1276 12239 2 917.501012 459.7589 DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1 8.22 2811.5 - 1.97E+06 - - - -2.4163 - 1.365 0.103 - 222.1 1 2 0 -0.0022 7 0 0 0 1.20E+08 8.70E+07 - - - 0.787 0.9895 230117_WJC_METTL3_WT_vs_EV_F01.12241.12241.2 0.0908 12-Jun K.LSIVPVR[166.11].R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 792.5097 0.87 1277 12241 2 792.508545 397.2621 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2811.7 - 3.97E+07 - - - -1.4498 - 1.392 0.177 - 130.3 1 2 0 -0.0011 7 0 0 0 3.52E+09 4.04E+09 - - - 1.3959 0.999 230117_WJC_METTL3_WT_vs_EV_F01.12273.12273.2 0.0036 20-Nov R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 398.45 1285 12273 2 1264.628517 633.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2816.2 - 774289 - - - -1.1189 - 2.019 0.393 - 325.4 1 2 0 -0.0014 11 0 0 0 2.68E+07 6.73E+04 - - - 3.844 0.8556 230117_WJC_METTL3_WT_vs_EV_F01.12286.12286.2 7 14-Aug R.MVDFAGVK.D "sp|P21964|COMT_HUMAN,tr|E7EUU8|E7EUU8_HUMAN,tr|E7EMS6|E7EMS6_HUMAN,tr|F8WBW9|F8WBW9_HUMAN,tr|H7BZ45|H7BZ45_HUMAN,tr|A0A7I2V3G7|A0A7I2V3G7_HUMAN,tr|A0A7I2V370|A0A7I2V370_HUMAN" 7 865.4368 1.18 1288 12286 2 865.435496 433.7257 Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT PE=1 SV=2 5.59 2818.1 - 2.90E+06 - - - -1.4779 - 0.99 0.065 - 112.7 1 2 0 -0.0013 8 0 0 0 1.29E+08 1.09E+08 - - - -0.5096 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.12293.12293.2 0.126 14-Aug K.IIGDTFVK[136.11].L sp|P49915|GUAA_HUMAN 1 899.5208 2.54 1289 12293 2 899.520453 450.7677 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.84 2819.2 - 2.04E+06 - - - -0.3513 - 1.374 0.301 - 132.1 1 2 0 -0.0003 8 0 0 0 3.40E+08 1.34E+08 - - - 2.2223 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.12302.12302.2 0.724 12-Jul K.LSIVPVR.R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 782.5014 0.87 1294 12302 2 782.501063 392.258 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2820.1 - 3.62E+07 - - - -0.4613 - 1.5 0.165 - 192.6 1 2 0 -0.0004 7 0 0 0 3.52E+09 4.04E+09 - - - 1.5443 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.12312.12312.2 0.00563 16-Sep K.VLEGMEVVR[166.11].K "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1040.5564 0.11 1297 12312 2 1040.556537 521.2855 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.53 2821.5 - 360976 - - - 0.1451 - 1.798 0.351 - 262.4 1 2 0 0.0002 9 0 0 0 7.06E+06 6.28E+07 - - - 3.3307 0.9928 230117_WJC_METTL3_WT_vs_EV_F01.12322.12322.2 15.4 12-Jul K.IILQTIK.W "sp|Q5VT40|FA78B_HUMAN,sp|O75909|CCNK_HUMAN,tr|H7C075|H7C075_HUMAN,tr|H7C3M6|H7C3M6_HUMAN,tr|G3V2Q3|G3V2Q3_HUMAN,tr|G3V5E1|G3V5E1_HUMAN" 6 827.548 0.88 1301 12322 2 827.549686 414.7813 Protein FAM78B OS=Homo sapiens OX=9606 GN=FAM78B PE=2 SV=1 8.75 2822.8 - 603128 - - - 1.989 - 1.374 0.099 - 108.4 1 2 0 0.0016 7 0 0 0 1.48E+07 1.68E+07 - - - 0.7784 0.8664 230117_WJC_METTL3_WT_vs_EV_F01.12326.12326.2 0.0078 12-Jul R.PVWADYR[166.11].R "sp|Q9Y676|RT18B_HUMAN,tr|A0A0G2JIC6|A0A0G2JIC6_HUMAN" 2 915.4478 1.23 1302 12326 2 915.449001 458.7312 "28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1" 6.26 2823.4 - 1.20E+06 - - - 1.2879 - 1.231 0.277 - 177.2 1 1 0 0.0012 7 0 0 0 5.49E+07 4.47E+07 - - - 1.7451 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.12334.12334.2 0.039 12-Jul K.YLYEIAR.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 926.4862 42.62 1307 12334 2 926.486508 464.2504 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6 2824.3 - 7.65E+06 - - - 0.367 - 1.393 0.275 - 182.4 1 2 0 0.0003 7 0 0 0 8.49E+08 1.99E+07 - - - 2.1223 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.12354.12354.2 0.000115 12-Sep R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.26 1317 12354 2 852.484393 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2827 - 6.57E+07 - - - 0.8657 - 1.685 0.353 - 238.4 1 2 0 0.0007 7 0 0 0 1.17E+10 9.23E+09 - - - 3.3013 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.12357.12357.2 0.408 14-Jul K.IIGDTFVK.L sp|P49915|GUAA_HUMAN 1 891.5066 2.52 1319 12357 2 891.507674 446.7606 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.84 2827.3 - 2.92E+06 - - - 1.2395 - 1.41 0.206 - 106.3 1 2 0 0.0011 8 0 0 0 3.49E+08 1.38E+08 - - - 1.5984 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.12362.12362.2 9.48E-05 18-Sep K.FGEVVDC[160.03]TIK.M "sp|Q99729|ROAA_HUMAN,sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 13 1166.5642 1.7 1321 12362 2 1166.564019 584.2894 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 4.37 2827.9 - 264565 - - - -0.1217 - 1.785 0.511 - 255.1 1 2 0 -0.0001 10 0 0 0 9.74E+06 5.72E+06 - - - 4.4325 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.12370.12370.2 0.0754 14-Sep R.LADIVVPR.G sp|Q9NWZ5|UCKL1_HUMAN 1 881.5335 4 1325 12370 2 881.534701 441.774 Uridine-cytidine kinase-like 1 OS=Homo sapiens OX=9606 GN=UCKL1 PE=1 SV=2 5.84 2828.9 - 416167 - - - 1.4168 - 1.962 0.249 - 236.4 1 2 0 0.0012 8 0 0 0 2.02E+07 5.05E+06 - - - 2.9124 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.12385.12385.2 0.00194 12-Aug R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.34 1331 12385 2 844.47147 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2830.9 - 5.81E+07 - - - 2.3861 - 1.582 0.333 - 206.8 1 2 0 0.002 7 0 0 0 1.36E+10 1.02E+10 - - - 2.9533 0.9 230117_WJC_METTL3_WT_vs_EV_F01.12399.12399.2 0.0173 14-Jul A.LLPALAAR[166.11].G "sp|P46531|NOTC1_HUMAN,sp|Q86Y56|DAAF5_HUMAN,sp|P08582|TRFM_HUMAN,tr|A0A7P0T8U6|A0A7P0T8U6_HUMAN,tr|A0A7P0TAK8|A0A7P0TAK8_HUMAN,tr|A0A7P0TB20|A0A7P0TB20_HUMAN,tr|A0A7P0T8W1|A0A7P0T8W1_HUMAN,tr|A0A7P0Z4H9|A0A7P0Z4H9_HUMAN,tr|A0A7P0T9V1|A0A7P0T9V1_HUMAN,tr|A0A7P0TBG2|A0A7P0TBG2_HUMAN" 10 833.5362 1.38 1339 12399 2 833.53785 417.7754 Neurogenic locus notch homolog protein 1 OS=Homo sapiens OX=9606 GN=NOTCH1 PE=1 SV=4 9.75 2832.6 - 549306 - - - 1.9279 - 1.3 0.311 - 119.1 1 1 0 0.0016 8 0 0 0 5.32E+07 3.86E+07 - - - 2.1288 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.12436.12436.2 8.62E-06 20-Oct R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 81.17 1357 12436 2 1201.611307 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2837.5 - 238808 - - - 1.8059 - 1.88 0.472 - 224.6 1 2 0 0.0022 11 0 0 0 1.87E+07 2.30E+05 - - - 4.2342 0.9919 230117_WJC_METTL3_WT_vs_EV_F01.12465.12465.2 2.55 12-Jul R.LLSVNIR.V sp|P07814|SYEP_HUMAN 1 813.5072 1.44 1368 12465 2 813.507614 407.7609 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 9.75 2841.6 - 2.52E+06 - - - 0.4622 - 1.396 0.087 - 146.3 1 2 0 0.0004 7 0 0 0 3.18E+08 2.22E+08 - - - 0.7405 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.12467.12467.2 0.00192 24-Aug R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 1370 12467 2 1302.609886 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2841.8 - 129969 - - - 0.5297 - 1.41 0.433 - 112 1 2 0 0.0007 13 0 0 0 9.30E+06 0.00E+00 - - - 3.1208 0.9708 230117_WJC_METTL3_WT_vs_EV_F01.12482.12482.2 0.000245 16-Sep R.PLISVYSEK.G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1034.5648 0.8 1374 12482 2 1034.567157 518.2897 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.42 2844 - 1.41E+06 - - - 2.2667 - 1.793 0.451 - 340.6 1 1 0 0.0023 9 0 0 0 5.91E+07 7.35E+07 - - - 4.0606 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.12501.12501.2 0.00247 18-Sep K.DVNAAIATIK.T "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 8 1014.571 5.11 1379 12501 2 1014.572247 508.2928 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 5.84 2846.8 - 372885 - - - 1.2685 - 2 0.4 - 214.4 1 2 0 0.0013 10 0 0 0 2.61E+07 5.12E+06 - - - 3.9298 0.9937 230117_WJC_METTL3_WT_vs_EV_F01.12514.12514.2 0.102 14-Sep R.LPLQDVYK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 974.5437 6.02 1381 12514 2 974.548456 488.2791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2848.8 - 382043 - - - 4.8977 - 1.552 0.278 - 204 1 2 0 0.0048 8 0 0 0 2.95E+09 4.90E+08 - - - 2.4185 0.8779 230117_WJC_METTL3_WT_vs_EV_F01.12534.12534.2 1.13 12-Jun K.TC[160.03]PLLLR[166.11].V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 881.5032 1.26 1393 12534 2 881.501597 441.7589 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2851.3 - 722374 - - - -1.8514 - 1.218 0.013 - 116.8 1 2 0 -0.0016 7 0 0 0 1.51E+09 1.20E+09 - - - -0.2386 0.9918 230117_WJC_METTL3_WT_vs_EV_F01.12542.12542.2 0.218 14-Jul K.AGLYGLPR[166.11].R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|A0A0U1RRG3|A0A0U1RRG3_HUMAN" 3 855.4842 2.14 1396 12542 2 855.486354 428.7494 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.79 2852.4 - 426383 - - - 2.5085 - 1.325 0.159 - 95.7 3 2 0 0.0021 8 0 0 0 4.95E+08 2.31E+08 - - - 0.8503 0.9973 230117_WJC_METTL3_WT_vs_EV_F01.12547.12547.2 0.014 12-Jul K.TC[160.03]PLLLR.V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 871.495 1.25 1398 12547 2 871.494166 436.7548 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2853.1 - 1.36E+06 - - - -0.9099 - 1.436 0.291 - 225.4 1 2 0 -0.0008 7 0 0 0 1.51E+09 1.20E+09 - - - 2.3367 0.9921 230117_WJC_METTL3_WT_vs_EV_F01.12548.12548.2 0.385 12-Jun K.VLFTVGK.L sp|Q9Y4C2|TCAF1_HUMAN 1 762.464 1.93 1399 12548 2 762.466158 382.2393 TRPM8 channel-associated factor 1 OS=Homo sapiens OX=9606 GN=TCAF1 PE=1 SV=3 8.72 2853.2 - 789047 - - - 2.8618 - 1.339 0.143 - 109.7 1 2 0 0.0022 7 0 0 0 2.72E+07 1.41E+07 - - - 1.0215 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.12550.12550.2 0.873 14-Aug R.LPLQDVYK[136.11].L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 982.5579 5.99 1401 12550 2 982.559686 492.2862 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2853.4 - 702582 - - - 1.835 - 1.657 0.134 - 198.1 1 2 0 0.0018 8 0 0 0 2.94E+09 4.90E+08 - - - 1.5532 0.992 230117_WJC_METTL3_WT_vs_EV_F01.12554.12554.2 1.74 12-Jun R.GDIQTLK[136.11].N sp|Q9HC62|SENP2_HUMAN 1 781.4425 1.02 1403 12554 2 781.443165 391.7285 Sentrin-specific protease 2 OS=Homo sapiens OX=9606 GN=SENP2 PE=1 SV=3 5.84 2853.9 - 1.49E+06 - - - 0.8267 - 1.188 0.147 - 182.2 1 2 0 0.0006 7 0 0 0 6.37E+08 6.26E+08 - - - 0.6724 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.12555.12555.2 0.253 12-Jun R.IGTFDLK.Y "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN" 2 792.4382 0.24 1404 12555 2 792.439224 397.2264 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 5.84 2854 - 1.16E+06 - - - 1.349 - 1.271 0.229 - 68.7 1 2 0 0.0011 7 0 0 0 2.42E+07 1.02E+08 - - - 1.4919 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.12558.12558.2 0.181 18-Jul R.SINQPVAFVR.R "sp|Q9GZT3|SLIRP_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|H0YJI1|H0YJI1_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1129.6244 1.06 1407 12558 2 1129.626553 565.8195 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 9.47 2854.4 - 110722 - - - 1.9121 - 1.38 0.181 - 118.4 1 2 0 0.0022 10 0 0 0 5.18E+06 4.88E+06 - - - 1.2762 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.12560.12560.2 0.0388 14-Aug K.LIGEYGLR.N "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 919.5127 0.8 1408 12560 2 919.514368 460.7636 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 2854.6 - 5.23E+07 - - - 1.7955 - 1.632 0.14 - 174.6 1 2 0 0.0017 8 0 0 0 2.80E+09 3.48E+09 - - - 1.5518 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.12562.12562.2 0.242 12-Jun K.INAEFLR.A "sp|Q15276|RABE1_HUMAN,tr|I3L2B8|I3L2B8_HUMAN" 2 861.4709 0.82 1409 12562 2 861.470358 431.7427 Rab GTPase-binding effector protein 1 OS=Homo sapiens OX=9606 GN=RABEP1 PE=1 SV=2 6 2854.8 - 270358 - - - -0.5734 - 1.369 0.19 - 75.1 1 2 0 -0.0005 7 0 0 0 2.02E+07 2.46E+07 - - - 1.4394 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.12568.12568.2 0.000691 16-Sep R.LYEALTPVH.- "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1041.5495 - 1412 12568 2 1041.551743 521.782 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.24 2855.6 - 780536 - - - 2.1574 - 1.593 0.41 - 283.9 1 2 0 0.0022 9 0 0 0 - - - - - 3.4156 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.12607.12607.2 0.119 14-Sep K.AGLYGLPR.R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|A0A0U1RRG3|A0A0U1RRG3_HUMAN" 3 845.4759 2.36 1424 12607 2 845.476087 423.7452 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.79 2861.2 - 9.20E+06 - - - 0.1762 - 1.913 0.323 - 280.9 1 2 0 0.0001 8 0 0 0 5.44E+08 2.31E+08 - - - 3.383 0.9938 230117_WJC_METTL3_WT_vs_EV_F01.12616.12616.2 0.154 14-Jul K.IPYTTVLR.L "sp|Q08945|SSRP1_HUMAN,tr|E9PMD4|E9PMD4_HUMAN" 2 961.5597 0.25 1429 12616 2 961.559268 481.7871 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 8.75 2862.2 - 557965 - - - -0.415 - 1.341 0.185 - 162.8 1 2 0 -0.0004 8 0 0 0 1.39E+08 5.63E+08 - - - 1.2922 0.9939 230117_WJC_METTL3_WT_vs_EV_F01.12638.12638.2 1.38 12-Jul R.WLGEPIK.A "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 841.4698 0.46 1437 12638 2 841.470117 421.7422 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6 2865.1 - 5.78E+06 - - - 0.3886 - 1.154 0.201 - 248.5 1 2 0 0.0003 7 0 0 0 1.49E+09 3.25E+09 - - - 0.9793 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.12640.12640.4 3.84E-07 17/108 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 3.11 1439 12640 4 2080.024598 521.0129 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2865.4 - 601439 - - - 0.9928 - 2.792 0.514 - 240.8 1 2 0 0.0021 19 0 0 0 4.48E+07 1.44E+07 - - - 4.0466 0.9918 230117_WJC_METTL3_WT_vs_EV_F01.12653.12653.2 0.0808 16-Sep K.AGLAPLEVR.V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 924.5393 0.84 1444 12653 2 924.538592 463.2769 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.05 2867.1 - 465131 - - - -0.729 - 1.625 0.106 - 204.1 1 2 0 -0.0007 9 0 0 0 1.38E+08 1.64E+08 - - - 1.2283 0.9939 230117_WJC_METTL3_WT_vs_EV_F01.12655.12655.2 0.0773 16-Aug K.AGLAPLEVR[166.11].V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 934.5475 0.75 1445 12655 2 934.548595 468.281 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.05 2867.3 - 522785 - - - 1.1332 - 1.626 0.052 - 168.5 1 2 0 0.0011 9 0 0 0 2.97E+07 3.97E+07 - - - 0.8311 1 230117_WJC_METTL3_WT_vs_EV_F01.12657.12657.3 4.83E-07 15/72 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 4.57 1447 12657 3 2080.016962 694.3481 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2867.5 - 265214 - - - -2.6783 - 2.793 0.607 - 229 1 2 0 -0.0056 19 0 0 0 1.18E+07 2.57E+06 - - - 7.8293 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.12658.12658.2 4.26E-05 20-Nov R.TAAENDFVTLK.K sp|P35908|K22E_HUMAN 1 1207.6085 9.95 1448 12658 2 1207.611165 604.8115 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2867.7 - 162232 - - - 2.2333 - 2.151 0.386 - 320.8 1 2 0 0.0027 11 0 0 0 4.59E+06 4.61E+05 - - - 3.9632 0.8763 230117_WJC_METTL3_WT_vs_EV_F01.12663.12663.2 0.0151 14-Jun L.VDHALIAR[166.11].C sp|Q05BV3|EMAL5_HUMAN 1 903.5166 4.04 1451 12663 2 903.517246 452.7656 Echinoderm microtubule-associated protein-like 5 OS=Homo sapiens OX=9606 GN=EML5 PE=2 SV=3 6.71 2868.2 - 1.50E+06 - - - 0.7482 - 1.293 0.282 - 142.8 1 1 0 0.0007 8 0 0 0 2.12E+08 5.24E+07 - - - 1.8986 0.9714 230117_WJC_METTL3_WT_vs_EV_F01.12669.12669.2 10.9 16-Jul K.LVPVGYGIR[166.11].K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 982.5839 0.98 1455 12669 2 982.584808 492.2992 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2868.9 - 8.09E+06 - - - 0.9017 - 1.15 0.047 - 155.9 1 2 0 0.0009 9 0 0 0 9.12E+08 9.32E+08 - - - -0.2078 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.12674.12674.2 0.648 16-Jul K.IGPLGLSPK[136.11].K sp|P30050|RL12_HUMAN 1 888.5524 1.64 1456 12674 2 888.552066 445.2835 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2869.6 - 3.94E+06 - - - -0.3793 - 1.323 0.224 - 83.5 1 2 0 -0.0003 9 0 0 0 1.52E+10 9.31E+09 - - - 1.5051 0.999 230117_WJC_METTL3_WT_vs_EV_F01.12689.12689.2 0.00362 16-Oct K.IGPLGLSPK.K sp|P30050|RL12_HUMAN 1 880.5382 1.63 1464 12689 2 880.537862 441.2764 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2871.5 - 1.16E+07 - - - -0.3873 - 1.757 0.325 - 299.3 1 2 0 -0.0003 9 0 0 0 1.53E+10 9.38E+09 - - - 3.0719 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.12703.12703.2 0.753 12-Aug R.LAILYAK.R "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 790.4953 1.13 1469 12703 2 790.495585 396.2549 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 8.59 2873.3 - 1.23E+06 - - - 0.3909 - 1.765 0.101 - 195.2 1 2 0 0.0003 7 0 0 0 3.06E+08 2.70E+08 - - - 1.5871 0.9733 230117_WJC_METTL3_WT_vs_EV_F01.12714.12714.2 1.8 16-Jul K.LVPVGYGIR.K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 972.5757 0.98 1472 12714 2 972.575124 487.2951 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2874.8 - 1.66E+07 - - - -0.5429 - 1.16 0.109 - 176.5 1 2 0 -0.0005 9 0 0 0 9.15E+08 9.37E+08 - - - 0.2753 0.9858 230117_WJC_METTL3_WT_vs_EV_F01.12721.12721.2 0.526 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 121.02 1475 12721 2 776.380747 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2875.7 - 1.05E+06 - - - -1.2314 - 1.377 0.134 - 160.1 1 2 0 -0.001 7 0 0 0 1.36E+09 1.12E+07 - - - 1.0441 0.9954 230117_WJC_METTL3_WT_vs_EV_F01.12731.12731.2 0.92 14-Oct R.LGNSLLLK.Y sp|Q10570|CPSF1_HUMAN 1 856.5382 0.43 1478 12731 2 856.537564 429.2764 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 2877 - 2.01E+06 - - - -0.746 - 1.48 0.203 - 180.2 1 2 0 -0.0006 8 0 0 0 1.44E+08 3.31E+08 - - - 1.7225 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.12756.12756.2 1.37 12-Sep K.TAISLLR[166.11].N sp|Q99959|PKP2_HUMAN 1 782.489 0.93 1483 12756 2 782.489829 392.2518 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 9.41 2880.8 - 1.97E+06 - - - 1.1118 - 1.651 0.142 - 271.1 1 2 0 0.0009 7 0 0 0 1.06E+08 1.14E+08 - - - 1.6782 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.12758.12758.2 0.466 18-Sep R.LIAAATSVLK[136.11].T "sp|P24863|CCNC_HUMAN,tr|E5RFX8|E5RFX8_HUMAN,tr|E5RI39|E5RI39_HUMAN,tr|J3KP90|J3KP90_HUMAN,tr|E5RFK5|E5RFK5_HUMAN,tr|G5E954|G5E954_HUMAN,tr|H0YBQ5|H0YBQ5_HUMAN" 7 993.6314 1.27 1485 12758 2 993.631375 497.823 Cyclin-C OS=Homo sapiens OX=9606 GN=CCNC PE=1 SV=2 8.75 2881.1 - 650121 - - - -0.007 - 1.854 0.329 - 130.2 1 2 0 0 10 0 0 0 1.63E+07 1.28E+07 - - - 3.1942 0.8621 230117_WJC_METTL3_WT_vs_EV_F01.12759.12759.2 5.18 12-May K.ILEYLDK[136.11].W "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|H0YI32|H0YI32_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 900.5048 0.04 1486 12759 2 900.505473 451.2597 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 4.37 2881.2 - 521543 - - - 0.764 - 0.953 0.031 - 48.5 6 2 0 0.0007 7 0 0 0 2.11E+07 5.95E+08 - - - -1.2304 0.9884 230117_WJC_METTL3_WT_vs_EV_F01.12764.12764.2 1.11 14-Aug K.TALLGLTK[136.11].T sp|Q9BTZ2|DHRS4_HUMAN 1 823.5259 0.95 1488 12764 2 823.525451 412.7702 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 8.41 2881.8 - 3.01E+06 - - - -0.4894 - 1.474 0.086 - 272.4 1 2 0 -0.0004 8 0 0 0 9.23E+08 9.69E+08 - - - 0.8462 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.12765.12765.2 1.42 14-Sep R.LPVDIAYK.R sp|P15924|DESP_HUMAN 1 917.5222 5.42 1489 12765 2 917.521832 459.7684 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.83 2882 - 1.82E+06 - - - -0.4218 - 1.499 0.17 - 262.8 1 2 0 -0.0004 8 0 0 0 4.19E+08 7.73E+07 - - - 1.5174 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.12770.12770.2 0.143 14-Aug K.FGGVVELR.M sp|P49247|RPIA_HUMAN 1 875.4865 1.15 1491 12770 2 875.487106 438.7505 Ribose-5-phosphate isomerase OS=Homo sapiens OX=9606 GN=RPIA PE=1 SV=3 6 2882.6 - 1.72E+06 - - - 0.6899 - 1.713 0.187 - 178 2 2 0 0.0006 8 0 0 0 2.17E+08 1.90E+08 - - - 1.9108 0.9375 230117_WJC_METTL3_WT_vs_EV_F01.12792.12792.2 0.0847 14-Oct D.IADIEALK.E "sp|Q70CQ2|UBP34_HUMAN,sp|O75792|RNH2A_HUMAN,tr|A0A2R8Y606|A0A2R8Y606_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 4 871.5015 1.76 1502 12792 2 871.501654 436.758 Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens OX=9606 GN=USP34 PE=1 SV=2 4.37 2885.2 - 5.10E+06 - - - 0.1951 - 1.868 0.27 - 261.2 1 1 0 0.0002 8 0 0 0 4.37E+08 2.48E+08 - - - 2.9197 0.9864 230117_WJC_METTL3_WT_vs_EV_F01.12803.12803.2 3.44 12-Jul R.LVNQWIK[136.11].Q "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 907.5371 0.66 1507 12803 2 907.536737 454.7758 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 8.75 2886.6 - 916112 - - - -0.3868 - 1.257 0.124 - 111.4 1 2 0 -0.0004 7 0 0 0 3.29E+07 5.03E+07 - - - 0.6815 0.9944 230117_WJC_METTL3_WT_vs_EV_F01.12840.12840.2 0.307 20-Sep K.LIADVAPSAIR[166.11].E "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1134.6636 1.65 1517 12840 2 1134.667137 568.3391 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 5.84 2891.9 - 246656 - - - 3.0917 - 1.36 0.207 - 215.9 1 2 0 0.0035 11 0 0 0 5.33E+07 3.22E+07 - - - 1.4006 0.9864 230117_WJC_METTL3_WT_vs_EV_F01.12843.12843.2 0.0453 18-Jun R.LGPSVVGLAR[166.11].Y "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 977.5897 1.33 1518 12843 2 977.590846 489.8021 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 9.75 2892.3 - 180599 - - - 1.1365 - 1.389 0.096 - 61.4 8 2 0 0.0011 10 0 0 0 4.69E+07 3.52E+07 - - - 0.2635 0.9901 230117_WJC_METTL3_WT_vs_EV_F01.12849.12849.2 0.779 12-Jun K.LYALDVR.V "sp|O94913|PCF11_HUMAN,tr|E9PKN0|E9PKN0_HUMAN,tr|E9PQF9|E9PQF9_HUMAN,tr|E9PQ01|E9PQ01_HUMAN" 4 848.4756 0.87 1521 12849 2 848.476103 425.2451 Pre-mRNA cleavage complex 2 protein Pcf11 OS=Homo sapiens OX=9606 GN=PCF11 PE=1 SV=3 5.84 2892.9 - 350506 - - - 0.5893 - 1.381 0.086 - 90.7 2 2 0 0.0005 7 0 0 0 2.79E+07 3.19E+07 - - - 0.5644 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.12856.12856.2 0.165 18-Oct R.ISGLIYEETR[166.11].G sp|P62805|H4_HUMAN 1 1189.6218 0.64 1525 12856 2 1189.623189 595.8182 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2893.8 - 212865 - - - 1.1483 - 2.368 0.327 - 304.6 1 2 0 0.0014 10 0 0 0 9.60E+06 1.51E+07 - - - 3.862 0.9932 230117_WJC_METTL3_WT_vs_EV_F01.12858.12858.2 0.0929 20-Jul R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 999 1526 12858 2 1068.658163 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 2894 - 6.34E+06 - - - 3.6186 - 1.636 0.192 - 100.7 4 2 0 0.0039 11 0 0 0 7.52E+08 0.00E+00 - - - 1.5206 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.12877.12877.2 0.00202 18-Sep R.LGPSVVGLAR.Y "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 967.5815 1.33 1532 12877 2 967.580075 484.798 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 9.75 2896.6 - 742029 - - - -1.4366 - 1.879 0.398 - 185 1 2 0 -0.0014 10 0 0 0 4.69E+07 3.52E+07 - - - 3.7408 0.9574 230117_WJC_METTL3_WT_vs_EV_F01.12881.12881.2 5.5 14-Jul K.ILGDLSYR.S "sp|Q9NVC6|MED17_HUMAN,tr|A0A1W2PNF3|A0A1W2PNF3_HUMAN,tr|E9PM72|E9PM72_HUMAN,tr|A0A1W2PQ48|A0A1W2PQ48_HUMAN,tr|A0A1W2PS27|A0A1W2PS27_HUMAN,tr|A0A1W2PR99|A0A1W2PR99_HUMAN,tr|A0A1W2PRB8|A0A1W2PRB8_HUMAN,tr|A0A1W2PPP8|A0A1W2PPP8_HUMAN,tr|A0A1W2PNW7|A0A1W2PNW7_HUMAN,tr|A0A1W2PS69|A0A1W2PS69_HUMAN,tr|A0A1W2PRX4|A0A1W2PRX4_HUMAN" 11 935.5076 1.26 1535 12881 2 935.5067 468.7611 Mediator of RNA polymerase II transcription subunit 17 OS=Homo sapiens OX=9606 GN=MED17 PE=1 SV=2 5.84 2897.1 - 842002 - - - -0.9963 - 1.208 0.072 - 111.7 1 2 0 -0.0009 8 0 0 0 2.65E+07 2.10E+07 - - - 0.1424 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.12896.12896.2 0.00426 14-Sep K.LGIYEAMK.L sp|P15924|DESP_HUMAN 1 923.4786 2.95 1541 12896 2 923.478035 462.7466 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 2899 - 2.72E+06 - - - -0.6551 - 1.779 0.253 - 195.8 1 2 0 -0.0006 8 0 0 0 2.10E+08 7.12E+07 - - - 2.6468 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.12897.12897.2 0.0072 16-Sep R.LVPLVNGVR.E "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 965.6022 2.78 1542 12897 2 965.601786 483.8084 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 9.75 2899.1 - 1.20E+06 - - - -0.4298 - 1.591 0.212 - 244.4 1 2 0 -0.0004 9 0 0 0 1.26E+08 4.51E+07 - - - 1.9501 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.12910.12910.2 2.22 16-Oct K.AIPLALEGK[136.11].D "sp|Q9NY93|DDX56_HUMAN,tr|F8WDT8|F8WDT8_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|F8WEI3|F8WEI3_HUMAN" 4 918.563 1.19 1549 12910 2 918.562963 460.2888 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 6.05 2900.8 - 566259 - - - -0.0054 - 1.613 0.149 - 273.9 1 2 0 0 9 0 0 0 3.46E+07 2.91E+07 - - - 1.5247 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.12915.12915.2 0.0684 14-Aug K.LGIYEAMK.L sp|P15924|DESP_HUMAN 1 923.4786 2.95 1551 12915 2 923.478964 462.7466 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 2901.5 - 1.30E+06 - - - 0.3508 - 1.602 0.279 - 149.1 1 2 0 0.0003 8 0 0 0 2.10E+08 7.12E+07 - - - 2.5229 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.12919.12919.2 0.00239 16-Sep K.IGPLGLSPK.K sp|P30050|RL12_HUMAN 1 880.5382 1.63 1554 12919 2 880.538829 441.2764 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2901.9 - 1.30E+06 - - - 0.7109 - 1.738 0.318 - 204.7 1 2 0 0.0006 9 0 0 0 1.53E+10 9.38E+09 - - - 2.9886 0.9135 230117_WJC_METTL3_WT_vs_EV_F01.12921.12921.2 2.22 12-May R.EFVTAFK[136.11].K "sp|P13667|PDIA4_HUMAN,tr|A0A499FI48|A0A499FI48_HUMAN" 2 848.4524 6.5 1555 12921 2 848.454339 425.2335 Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2 6.1 2902.1 - 222035 - - - 2.3384 - 0.879 0.094 - 57.4 2 2 0 0.002 7 0 0 0 3.13E+08 4.81E+07 - - - -0.8085 0.9948 230117_WJC_METTL3_WT_vs_EV_F01.12923.12923.2 0.215 12-Sep K.TELLGLK.E sp|Q69YU5|BWNIN_HUMAN 1 772.4695 1.37 1557 12923 2 772.470991 387.242 Protein BRAWNIN OS=Homo sapiens OX=9606 GN=BRAWNIN PE=1 SV=2 5.66 2902.4 - 1.73E+06 - - - 1.9884 - 1.426 0.115 - 359.5 1 2 0 0.0015 7 0 0 0 5.95E+07 4.34E+07 - - - 1.0143 0.9433 230117_WJC_METTL3_WT_vs_EV_F01.12928.12928.2 2.15 12-Aug R.FGILTEK.Y "sp|Q16134|ETFD_HUMAN,tr|B4DEQ0|B4DEQ0_HUMAN,tr|A0A804HK05|A0A804HK05_HUMAN,tr|A0A804HJT7|A0A804HJT7_HUMAN,tr|A0A804HI48|A0A804HI48_HUMAN,tr|A0A804HK66|A0A804HK66_HUMAN,tr|A0A804HL81|A0A804HL81_HUMAN,tr|A0A804HJK8|A0A804HJK8_HUMAN,tr|A0A804HI73|A0A804HI73_HUMAN,tr|A0A804HL84|A0A804HL84_HUMAN" 10 806.4538 63.09 1560 12928 2 806.458262 404.2342 "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=ETFDH PE=1 SV=2" 6 2903 - 700265 - - - 5.5267 - 1.226 0.157 - 153.6 1 2 0 0.0045 7 0 0 0 1.72E+09 2.73E+07 - - - 0.8448 0.9328 230117_WJC_METTL3_WT_vs_EV_F01.12929.12929.2 0.837 16-May R.YVMVGLASR[166.11].R "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1004.5353 0.86 1561 12929 2 1004.533801 503.2749 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 8.75 2903.1 - 199766 - - - -1.4494 - 1.042 0.145 - 67.3 3 2 0 -0.0015 9 0 0 0 1.70E+07 1.96E+07 - - - 0.0174 0.999 230117_WJC_METTL3_WT_vs_EV_F01.12936.12936.2 0.00157 16-Aug K.AFADPEVLR.R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1016.5291 3.32 1566 12936 2 1016.531772 509.2718 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2903.9 - 474950 - - - 2.6335 - 1.446 0.373 - 224.4 1 2 0 0.0027 9 0 0 0 9.70E+07 2.92E+07 - - - 2.8621 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.12938.12938.2 2.33E-07 26-Nov R.LVPGGGATEIELAK.Q sp|P50990|TCPQ_HUMAN 1 1353.7504 20.04 1568 12938 2 1353.753481 677.8825 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 2904.2 - 371341 - - - 2.2899 - 2.102 0.494 - 285.8 1 2 0 0.0031 14 0 0 0 3.50E+07 1.75E+06 - - - 4.553 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.12940.12940.2 0.109 14-Jul K.QVEELFER[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1058.5272 2.77 1570 12940 2 1058.528896 530.2709 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2904.4 - 225216 - - - 1.6069 - 1.332 0.185 - 190.8 1 2 0 0.0017 8 0 0 0 3.58E+07 1.29E+07 - - - 1.2715 0.9722 230117_WJC_METTL3_WT_vs_EV_F01.12944.12944.2 0.00623 14-Aug K.FQNALLVR.Y "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 959.5553 114.23 1572 12944 2 959.561595 480.7849 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 9.75 2905 - 560214 - - - 6.6124 - 1.743 0.182 - 199.9 1 2 0 0.0063 8 0 0 0 1.38E+08 1.21E+06 - - - 2.0589 0.9892 230117_WJC_METTL3_WT_vs_EV_F01.12947.12947.2 4.22 12-May R.TILMMGR.Y sp|P13639|EF2_HUMAN 1 820.4299 1.47 1573 12947 2 820.43119 411.2222 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 9.41 2905.4 - 6.15E+06 - - - 1.5541 - 1.108 0.143 - 100.8 1 2 0 0.0013 7 0 0 0 1.78E+08 1.21E+08 - - - 0.4218 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.12951.12951.2 0.000342 16-Aug K.AFADPEVLR[166.11].R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1026.5374 3.2 1577 12951 2 1026.540857 514.276 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2905.9 - 601889 - - - 3.4017 - 1.447 0.433 - 219.4 1 2 0 0.0035 9 0 0 0 9.37E+07 2.92E+07 - - - 3.307 0.9913 230117_WJC_METTL3_WT_vs_EV_F01.12963.12963.2 1.21 14-Sep K.LISGWVSR[166.11].S "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 926.5213 1.47 1585 12963 2 926.523915 464.2679 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 9.75 2907.2 - 953956 - - - 2.7997 - 1.289 0.151 - 161.6 1 2 0 0.0026 8 0 0 0 7.40E+07 5.05E+07 - - - 0.9211 0.992 230117_WJC_METTL3_WT_vs_EV_F01.12964.12964.2 0.633 12-Jul R.LLEIVER.Q sp|Q12792|TWF1_HUMAN 1 870.5175 1.18 1586 12964 2 870.519868 436.266 Twinfilin-1 OS=Homo sapiens OX=9606 GN=TWF1 PE=1 SV=3 4.53 2907.2 - 725852 - - - 2.757 - 1.482 0.092 - 160.5 1 2 0 0.0024 7 0 0 0 5.94E+07 5.03E+07 - - - 0.9662 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.12965.12965.2 0.0841 14-Aug K.LISGWVSR.S "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 916.5131 1.47 1587 12965 2 916.516665 459.2638 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 9.75 2907.3 - 1.06E+06 - - - 3.9432 - 1.492 0.298 - 170.2 1 2 0 0.0036 8 0 0 0 7.37E+07 5.03E+07 - - - 2.4476 0.999 230117_WJC_METTL3_WT_vs_EV_F01.12970.12970.2 0.00267 20-Sep R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 999 1589 12970 2 1201.612572 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2908 - 191638 - - - 2.8587 - 1.436 0.407 - 181.4 1 2 0 0.0034 11 0 0 0 3.32E+06 0.00E+00 - - - 3.0249 0.928 230117_WJC_METTL3_WT_vs_EV_F01.12981.12981.2 2.06 12-Jun R.FPPYYMR[166.11].R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 982.461 0.73 1596 12981 2 982.463361 492.2378 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 2909.3 - 317422 - - - 2.3736 - 0.791 0.139 - 109.4 1 2 0 0.0023 7 0 0 0 2.90E+07 3.97E+07 - - - -0.676 0.9806 230117_WJC_METTL3_WT_vs_EV_F01.12984.12984.4 0.0259 15/96 T.LLLIILTDVFIISTVLR.L sp|Q8NGY0|O10X1_HUMAN 1 1941.2278 3.92 1597 12984 4 1941.236964 486.3142 Olfactory receptor 10X1 OS=Homo sapiens OX=9606 GN=OR10X1 PE=3 SV=2 5.84 2909.7 - 2.92E+06 - - - 4.7094 - 2.056 0.416 - 90.2 1 1 0 0.0091 17 0 0 0 1.43E+08 3.65E+07 - - - 3.0946 0.9871 230117_WJC_METTL3_WT_vs_EV_F01.12985.12985.2 0.65 18-Jul R.IITEGASILR.Q "sp|Q08209|PP2BA_HUMAN,tr|E9PPC8|E9PPC8_HUMAN,tr|E9PK68|E9PK68_HUMAN" 3 1071.6288 2.86 1598 12985 2 1071.630415 536.8217 Serine\threonine-protein phosphatase 2B catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP3CA PE=1 SV=1 6 2909.9 - 328825 - - - 1.4987 - 1.263 0.082 - 94.5 1 2 0 0.0016 10 0 0 0 1.02E+07 3.57E+06 - - - 0.2979 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.13001.13001.2 3 12-Jul R.VAIFIEK.T sp|Q9P258|RCC2_HUMAN 1 818.4902 1.78 1605 13001 2 818.490772 410.2524 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2911.9 - 1.55E+06 - - - 0.7098 - 1.292 0.193 - 169 1 2 0 0.0006 7 0 0 0 1.08E+08 6.04E+07 - - - 1.2781 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.13009.13009.2 0.521 12-Aug R.VAIFIEK[136.11].T sp|Q9P258|RCC2_HUMAN 1 826.5044 1.8 1608 13009 2 826.504828 414.2595 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2912.9 - 1.17E+06 - - - 0.5287 - 1.882 0.145 - 225.7 1 2 0 0.0004 7 0 0 0 1.08E+08 5.97E+07 - - - 2.1154 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.13018.13018.2 0.00908 16-Jul K.MLVVGGIDR.V sp|Q15046|SYK_HUMAN 1 958.527 1.08 1611 13018 2 958.527554 480.2708 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2914.1 - 5.74E+06 - - - 0.5915 - 1.546 0.348 - 233.8 1 2 0 0.0006 9 0 0 0 2.00E+08 1.85E+08 - - - 2.8716 0.9792 230117_WJC_METTL3_WT_vs_EV_F01.13019.13019.2 0.902 12-May K.VLLGELK.G sp|Q05655|KPCD_HUMAN 1 770.4902 2.83 1612 13019 2 770.490111 386.2524 Protein kinase C delta type OS=Homo sapiens OX=9606 GN=PRKCD PE=1 SV=2 5.97 2914.1 - 1.53E+06 - - - -0.1038 - 1.27 0.131 - 101.8 13 2 0 -0.0001 7 0 0 0 4.59E+07 1.62E+07 - - - 0.2683 0.9524 230117_WJC_METTL3_WT_vs_EV_F01.13026.13026.2 1.56 14-Jun R.ALEGLVYR.S "sp|Q9Y4R8|TELO2_HUMAN,tr|H3BU45|H3BU45_HUMAN" 2 919.5127 3.71 1614 13026 2 919.511268 460.7636 Telomere length regulation protein TEL2 homolog OS=Homo sapiens OX=9606 GN=TELO2 PE=1 SV=2 6.05 2915.1 - 751016 - - - -1.5758 - 1.263 0.106 - 92.5 3 2 0 -0.0014 8 0 0 0 6.39E+07 1.72E+07 - - - 0.3145 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.13032.13032.2 0.0621 16-Aug K.MLVVGGIDR[166.11].V sp|Q15046|SYK_HUMAN 1 968.5353 1.07 1617 13032 2 968.535106 485.2749 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2915.8 - 2.79E+06 - - - -0.1559 - 1.776 0.256 - 279.9 1 2 0 -0.0001 9 0 0 0 1.97E+08 1.85E+08 - - - 2.5934 0.9547 230117_WJC_METTL3_WT_vs_EV_F01.13033.13033.2 0.814 12-Jul K.VLEIPYK.G "sp|P48594|SPB4_HUMAN,sp|P29508|SPB3_HUMAN,tr|C9JZ65|C9JZ65_HUMAN,tr|H0Y5H9|H0Y5H9_HUMAN" 4 860.5008 8.37 1618 13033 2 860.498386 431.2577 Serpin B4 OS=Homo sapiens OX=9606 GN=SERPINB4 PE=1 SV=2 5.97 2915.9 - 2.11E+06 - - - -2.753 - 1.185 0.176 - 133 1 2 0 -0.0024 7 0 0 0 3.63E+08 4.34E+07 - - - 0.878 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.13038.13038.2 4.15E-05 18-Oct R.LVNHFVEEFK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1260.6503 0.54 1619 13038 2 1260.65539 631.3324 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2916.6 - 1.62E+06 - - - 4.059 - 1.77 0.456 - 218 1 2 0 0.0051 10 0 0 0 4.82E+07 8.93E+07 - - - 4.0012 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.13042.13042.2 0.00554 18-Nov R.RVLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1125.687 1.47 1620 13042 2 1125.687215 563.8508 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2917.2 - 872024 - - - 0.1972 - 2.042 0.309 - 221.3 1 2 0 0.0002 10 0 0 0 4.64E+07 3.15E+07 - - - 3.316 0.9524 230117_WJC_METTL3_WT_vs_EV_F01.13049.13049.2 1.52 12-Jun R.IFVDIEK[136.11].L "sp|P06737|PYGL_HUMAN,tr|E9PK47|E9PK47_HUMAN" 2 870.4942 3.35 1623 13049 2 870.493842 436.2544 "Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL PE=1 SV=4" 4.37 2918.1 - 365719 - - - -0.4342 - 1.22 0.059 - 67.9 4 2 0 -0.0004 7 0 0 0 7.77E+07 2.32E+07 - - - -0.1622 0.9835 230117_WJC_METTL3_WT_vs_EV_F01.13051.13051.2 0.314 14-Jul R.SPAQILLR[166.11].W "sp|P14550|AK1A1_HUMAN,sp|Q96JD6|AKCL2_HUMAN,tr|G3V1C1|G3V1C1_HUMAN" 3 906.5526 3.89 1625 13051 2 906.55301 454.2836 Aldo-keto reductase family 1 member A1 OS=Homo sapiens OX=9606 GN=AKR1A1 PE=1 SV=3 9.47 2918.4 - 729127 - - - 0.4291 - 1.257 0.089 - 79.6 2 2 0 0.0004 8 0 0 0 1.04E+08 2.68E+07 - - - 0.2536 0.9868 230117_WJC_METTL3_WT_vs_EV_F01.13069.13069.2 0.963 14-Jul K.FIINSYPK[136.11].Y "sp|Q96EY7|PTCD3_HUMAN,tr|B8ZZQ4|B8ZZQ4_HUMAN" 2 988.5473 0.73 1632 13069 2 988.548998 495.2809 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 8.59 2921 - 404898 - - - 1.6995 - 1.166 0.108 - 95.1 1 2 0 0.0017 8 0 0 0 1.62E+07 2.23E+07 - - - 0.3013 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.13074.13074.2 0.209 14-Aug R.QMAAVLLR[166.11].R "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 11 910.5298 1.22 1634 13074 2 910.529801 456.2722 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 2921.7 - 408911 - - - 0.0253 - 1.501 0.168 - 186.7 1 2 0 0 8 0 0 0 9.90E+07 8.09E+07 - - - 1.5067 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.13075.13075.2 0.00617 14-Sep K.VVLVLAGR[166.11].Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 835.5519 0.77 1635 13075 2 835.552166 418.7832 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2921.7 - 4.96E+06 - - - 0.3267 - 1.673 0.364 - 312.9 1 2 0 0.0003 8 0 0 0 2.71E+09 3.52E+09 - - - 3.2815 0.9934 230117_WJC_METTL3_WT_vs_EV_F01.13077.13077.2 0.108 18-Jul R.VNC[160.03]LAPGLIK[136.11].T "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN" 3 1091.6253 0.99 1637 13077 2 1091.626493 546.8199 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 8.19 2921.9 - 141857 - - - 1.1378 - 1.217 0.16 - 101.1 1 2 0 0.0012 10 0 0 0 1.17E+07 1.19E+07 - - - 0.7706 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.13080.13080.2 0.00564 14-Aug K.VVLVLAGR.Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 825.5436 0.77 1638 13080 2 825.543488 413.7791 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2922.3 - 5.26E+06 - - - -0.1635 - 1.84 0.321 - 343.2 1 2 0 -0.0001 8 0 0 0 2.72E+09 3.53E+09 - - - 3.2509 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.13088.13088.2 0.155 18-Jun R.LGLMPPPEPK.V sp|O43395|PRPF3_HUMAN 1 1077.5893 5.95 1641 13088 2 1077.590285 539.8019 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6 2923.3 - 132587 - - - 0.9577 - 1.422 0.252 - 96.3 1 2 0 0.001 10 0 0 0 2.63E+07 4.42E+06 - - - 1.8847 0.9927 230117_WJC_METTL3_WT_vs_EV_F01.13103.13103.2 0.0332 14-Jul K.LTPVLLAK[136.11].Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 861.5779 1.7 1646 13103 2 861.577671 431.7962 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2925.3 - 5.60E+06 - - - -0.2542 - 1.19 0.207 - 148.7 1 2 0 -0.0002 8 0 0 0 5.03E+08 2.96E+08 - - - 1.0945 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.13114.13114.2 0.00218 18-Sep R.VNC[160.03]LAPGLIK.T "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN" 3 1083.6111 0.99 1652 13114 2 1083.613437 542.8128 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 8.19 2926.7 - 465291 - - - 2.2019 - 1.767 0.239 - 248.9 1 2 0 0.0024 10 0 0 0 1.17E+07 1.19E+07 - - - 2.3945 0.9949 230117_WJC_METTL3_WT_vs_EV_F01.13135.13135.2 1.03 14-Sep K.LLAEVTLK[136.11].T "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 4 893.5677 2.63 1662 13135 2 893.569116 447.7911 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 6 2929.5 - 721743 - - - 1.5634 - 1.281 0.159 - 182.9 1 2 0 0.0014 8 0 0 0 2.15E+08 8.16E+07 - - - 0.9618 0.9942 230117_WJC_METTL3_WT_vs_EV_F01.13141.13141.2 0.178 12-Aug R.FASFIER.V sp|P07196|NFL_HUMAN 1 868.4443 1.4 1666 13141 2 868.442882 435.2294 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2930.3 - 768225 - - - -1.6363 - 1.532 0.221 - 214.3 1 2 0 -0.0014 7 0 0 0 1.38E+08 9.88E+07 - - - 2.0245 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.13146.13146.2 0.0352 14-Jul K.LLAEVTLK.T "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 4 885.5535 2.63 1668 13146 2 885.554625 443.784 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 6 2930.9 - 2.35E+06 - - - 1.2489 - 1.429 0.335 - 125.9 1 2 0 0.0011 8 0 0 0 2.15E+08 8.16E+07 - - - 2.5916 0.998 230117_WJC_METTL3_WT_vs_EV_F01.13147.13147.2 0.329 12-Aug R.FASFIER[166.11].V sp|P07196|NFL_HUMAN 1 878.4526 1.4 1669 13147 2 878.454333 440.2336 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2931 - 1.28E+06 - - - 2.0035 - 1.657 0.158 - 216.1 1 2 0 0.0018 7 0 0 0 1.39E+08 9.89E+07 - - - 1.8076 0.9851 230117_WJC_METTL3_WT_vs_EV_F01.13152.13152.2 2.58 12-Aug R.LSSFIVK.E sp|P24278|ZBT25_HUMAN 1 792.4745 0.82 1671 13152 2 792.473938 397.2445 Zinc finger and BTB domain-containing protein 25 OS=Homo sapiens OX=9606 GN=ZBTB25 PE=1 SV=2 8.75 2931.6 - 1.54E+06 - - - -0.7609 - 1.788 0.005 - 156.4 2 2 0 -0.0006 7 0 0 0 7.64E+07 9.27E+07 - - - 0.7845 0.9664 230117_WJC_METTL3_WT_vs_EV_F01.13166.13166.2 5.3 20-Jun K.YGQISEVVVVK[136.11].D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1227.6954 0.95 1678 13166 2 1227.699183 614.855 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2933.4 - 109007 - - - 3.0496 - 1.223 0.084 - 79.2 2 2 0 0.0037 11 0 0 0 6.96E+06 7.32E+06 - - - 0.0704 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.13171.13171.2 0.00725 20-Sep K.YGQISEVVVVK.D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1219.6812 0.95 1679 13171 2 1219.68443 610.8479 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2934.1 - 98334.5 - - - 2.6163 - 1.501 0.392 - 167.4 1 2 0 0.0032 11 0 0 0 6.96E+06 7.32E+06 - - - 3.034 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.13175.13175.2 0.513 14-Jul R.IFNTFGPR[166.11].M "sp|Q8NBZ7|UXS1_HUMAN,tr|C9JCB7|C9JCB7_HUMAN,tr|C9JFU6|C9JFU6_HUMAN,tr|C9JE50|C9JE50_HUMAN" 4 960.5057 0.73 1681 13175 2 960.506239 481.2601 UDP-glucuronic acid decarboxylase 1 OS=Homo sapiens OX=9606 GN=UXS1 PE=1 SV=1 9.75 2934.7 - 282661 - - - 0.5914 - 1.408 0.171 - 82.7 1 2 0 0.0006 8 0 0 0 4.41E+07 6.06E+07 - - - 1.3358 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.13180.13180.2 0.131 12-Jul K.FSAFLEK.E sp|P11216|PYGB_HUMAN 1 840.4382 1.52 1683 13180 2 840.438326 421.2264 "Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB PE=1 SV=5" 6 2935.5 - 625196 - - - 0.2035 - 1.305 0.218 - 97.6 1 2 0 0.0002 7 0 0 0 4.95E+07 3.26E+07 - - - 1.4946 0.9821 230117_WJC_METTL3_WT_vs_EV_F01.13185.13185.2 0.96 16-Aug R.LLPSALGVK[136.11].K "sp|Q12873|CHD3_HUMAN,tr|A0A5F9ZHX5|A0A5F9ZHX5_HUMAN" 2 904.5837 0.75 1686 13185 2 904.583489 453.2991 Chromodomain-helicase-DNA-binding protein 3 OS=Homo sapiens OX=9606 GN=CHD3 PE=1 SV=3 8.75 2936 - 338246 - - - -0.2377 - 1.188 0.12 - 106.6 1 2 0 -0.0002 9 0 0 0 2.02E+07 2.70E+07 - - - 0.4256 0.9949 230117_WJC_METTL3_WT_vs_EV_F01.13189.13189.2 0.489 12-Jul K.VLESVFR.L sp|Q9BYE7|PCGF6_HUMAN 1 848.4756 1.54 1688 13189 2 848.477405 425.2451 Polycomb group RING finger protein 6 OS=Homo sapiens OX=9606 GN=PCGF6 PE=1 SV=2 5.97 2936.5 - 1.10E+06 - - - 2.1238 - 1.151 0.214 - 148.2 1 2 0 0.0018 7 0 0 0 5.43E+07 3.53E+07 - - - 1.0666 0.938 230117_WJC_METTL3_WT_vs_EV_F01.13191.13191.2 2.4 12-Jul K.ILMEFNK[136.11].M sp|Q9UQE7|SMC3_HUMAN 1 901.4823 1.83 1689 13191 2 901.485447 451.7484 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2936.7 - 868553 - - - 3.5186 - 1.127 0.058 - 103.8 1 2 0 0.0032 7 0 0 0 8.24E+07 4.51E+07 - - - -0.1528 0.9973 230117_WJC_METTL3_WT_vs_EV_F01.13198.13198.2 0.384 14-Jul K.IADFGLAR.L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 861.4709 2.25 1692 13198 2 861.471111 431.7427 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2937.6 - 4.03E+06 - - - 0.3006 - 1.548 0.196 - 149 2 2 0 0.0003 8 0 0 0 1.56E+08 6.93E+07 - - - 1.672 0.9179 230117_WJC_METTL3_WT_vs_EV_F01.13200.13200.2 3.4 12-May K.ILMEFNK.M sp|Q9UQE7|SMC3_HUMAN 1 893.4681 1.4 1693 13200 2 893.470225 447.7413 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2937.8 - 1.92E+06 - - - 2.4064 - 0.948 0.069 - 51.3 2 2 0 0.0022 7 0 0 0 8.36E+07 5.95E+07 - - - -0.7537 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.13204.13204.2 2.23 14-Sep K.LALDYGIK[136.11].F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 899.5208 1.27 1695 13204 2 899.521925 450.7677 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 2938.3 - 818101 - - - 1.2851 - 1.713 0.115 - 180.4 1 2 0 0.0012 8 0 0 0 3.46E+07 2.72E+07 - - - 1.5134 0.9911 230117_WJC_METTL3_WT_vs_EV_F01.13209.13209.2 1.56 14-May K.VLPITVPK[136.11].S sp|Q9ULW0|TPX2_HUMAN 1 873.5779 2.05 1697 13209 2 873.578855 437.7962 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.72 2938.9 - 1.05E+06 - - - 1.1047 - 0.832 0.281 - 37 1 2 0 0.001 8 0 0 0 8.83E+07 4.30E+07 - - - 0.5615 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.13216.13216.2 5.23 14-Jul K.IGDFGLAR.D "sp|P08922|ROS1_HUMAN,sp|P07333|CSF1R_HUMAN,sp|P51617|IRAK1_HUMAN,sp|Q96PY6|NEK1_HUMAN,sp|P51955|NEK2_HUMAN,sp|Q6P3R8|NEK5_HUMAN,sp|Q16659|MK06_HUMAN,sp|P31152|MK04_HUMAN,tr|E9PIX7|E9PIX7_HUMAN,tr|H7C2I6|H7C2I6_HUMAN,tr|K7EN18|K7EN18_HUMAN,tr|A0A494C168|A0A494C168_HUMAN,tr|F6U4U2|F6U4U2_HUMAN,tr|H7C224|H7C224_HUMAN,tr|K7ELV1|K7ELV1_HUMAN,tr|Q5H8Y1|Q5H8Y1_HUMAN,tr|A0A3B3ITQ6|A0A3B3ITQ6_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 18 847.4552 2.25 1700 13216 2 847.455234 424.7349 Proto-oncogene tyrosine-protein kinase ROS OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3 5.84 2939.8 - 908866 - - - 0.0378 - 1.789 0.144 - 114.5 1 2 0 0 8 0 0 0 9.60E+07 4.27E+07 - - - 1.8588 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.13222.13222.2 0.0208 14-Jun R.IFNTFGPR.M "sp|Q8NBZ7|UXS1_HUMAN,tr|C9JCB7|C9JCB7_HUMAN,tr|C9JFU6|C9JFU6_HUMAN,tr|C9JE50|C9JE50_HUMAN" 4 950.4974 0.71 1704 13222 2 950.497755 476.256 UDP-glucuronic acid decarboxylase 1 OS=Homo sapiens OX=9606 GN=UXS1 PE=1 SV=1 9.75 2940.5 - 1.14E+06 - - - 0.3724 - 1.324 0.308 - 93.1 1 2 0 0.0004 8 0 0 0 4.12E+07 5.82E+07 - - - 2.1622 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.13225.13225.2 0.557 12-Jul R.LALEELR.S sp|Q99496|RING2_HUMAN 1 842.4862 1.02 1707 13225 2 842.486579 422.2504 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.53 2940.8 - 1.20E+06 - - - 0.4878 - 1.549 0.116 - 174.4 1 2 0 0.0004 7 0 0 0 3.24E+08 3.19E+08 - - - 1.2842 0.9557 230117_WJC_METTL3_WT_vs_EV_F01.13228.13228.2 0.00448 14-Aug E.ILNPLVSK.A "sp|Q6NUP7|PP4R4_HUMAN,sp|Q9BSC4|NOL10_HUMAN,tr|G3V431|G3V431_HUMAN" 3 882.5539 1.06 1708 13228 2 882.554128 442.2842 Serine\threonine-protein phosphatase 4 regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PPP4R4 PE=1 SV=1 8.75 2941.2 - 2.18E+06 - - - 0.3105 - 1.428 0.437 - 143.8 1 1 0 0.0003 8 0 0 0 1.19E+08 1.12E+08 - - - 3.3431 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.13242.13242.2 0.0947 16-Aug R.ILVLNGGYR.G "sp|O60870|KIN17_HUMAN,tr|S4R357|S4R357_HUMAN" 2 1003.5815 1.83 1716 13242 2 1003.583008 502.798 DNA\RNA-binding protein KIN17 OS=Homo sapiens OX=9606 GN=KIN PE=1 SV=2 8.75 2942.9 - 485777 - - - 1.5375 - 1.591 0.236 - 168.8 1 2 0 0.0015 9 0 0 0 2.37E+07 1.29E+07 - - - 2.127 0.9937 230117_WJC_METTL3_WT_vs_EV_F01.13249.13249.2 0.117 14-May K.VLPITVPK.S sp|Q9ULW0|TPX2_HUMAN 1 865.5637 2.05 1720 13249 2 865.564 433.7891 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.72 2943.7 - 2.16E+06 - - - 0.3581 - 1.124 0.213 - 75.3 1 2 0 0.0003 8 0 0 0 8.84E+07 4.30E+07 - - - 0.9667 0.9869 230117_WJC_METTL3_WT_vs_EV_F01.13260.13260.2 0.0901 14-May K.VVNPLFEK.R "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 944.5331 0.75 1727 13260 2 944.53525 473.2738 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.97 2945 - 241592 - - - 2.2572 - 1.117 0.189 - 51 6 2 0 0.0021 8 0 0 0 1.24E+08 1.65E+08 - - - 0.4224 0.9844 230117_WJC_METTL3_WT_vs_EV_F01.13261.13261.2 0.0229 16-Jul K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 23.97 1728 13261 2 1014.539412 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 2945.1 - 742900 - - - 4.7677 - 1.53 0.164 - 105 1 2 0 0.0048 9 0 0 0 9.82E+06 4.10E+05 - - - 1.4811 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.13265.13265.2 0.389 14-Nov K.INELLLAK[136.11].E "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 920.5786 2.78 1730 13265 2 920.580329 461.2966 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 6 2945.6 - 744362 - - - 1.8586 - 1.859 0.271 - 269.2 1 2 0 0.0017 8 0 0 0 7.34E+07 2.64E+07 - - - 2.9121 0.9956 230117_WJC_METTL3_WT_vs_EV_F01.13266.13266.2 0.17 14-Jul K.VLTISTLR.L "sp|Q12830|BPTF_HUMAN,tr|F5GXF5|F5GXF5_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN,tr|A0A0A0MR81|A0A0A0MR81_HUMAN" 6 901.5597 0.82 1731 13266 2 901.559579 451.7871 Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3 9.72 2945.7 - 631788 - - - -0.0976 - 1.308 0.213 - 117.8 1 2 0 -0.0001 8 0 0 0 7.24E+07 8.83E+07 - - - 1.424 0.8644 230117_WJC_METTL3_WT_vs_EV_F01.13268.13268.2 0.00983 16-Jul H.VVVLVATVR.A "sp|P11586|C1TC_HUMAN,sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 8 954.6226 2.91 1733 13268 2 954.625372 478.3186 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.72 2946 - 519532 - - - 2.9017 - 1.388 0.306 - 105.4 1 1 0 0.0028 9 0 0 0 2.59E+07 8.89E+06 - - - 2.2488 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.13276.13276.2 0.747 14-Sep K.VVNPLFEK[136.11].R "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 952.5473 0.75 1738 13276 2 952.548492 477.2809 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.97 2946.9 - 1.06E+06 - - - 1.2325 - 1.596 0.319 - 230.7 1 2 0 0.0012 8 0 0 0 1.25E+08 1.65E+08 - - - 2.8067 0.9915 230117_WJC_METTL3_WT_vs_EV_F01.13283.13283.2 0.127 14-Jul R.LFVGSIPK[136.11].S "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 867.5309 0.9 1743 13283 2 867.531197 434.7727 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.75 2947.7 - 918216 - - - 0.2962 - 1.277 0.133 - 126.9 1 2 0 0.0003 8 0 0 0 1.64E+09 1.82E+09 - - - 0.7607 0.9737 230117_WJC_METTL3_WT_vs_EV_F01.13292.13292.2 1.33 14-Jul K.EVVVTLMK[136.11].K "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IT88|A0A3B3IT88_HUMAN" 2 925.5398 0.91 1750 13292 2 925.542736 463.7772 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 6.1 2948.9 - 562244 - - - 3.183 - 1.009 0.166 - 88 1 2 0 0.0029 8 0 0 0 5.76E+06 6.34E+06 - - - 0.2932 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.13296.13296.2 0.139 12-Jul R.NLPMHLR.R "sp|Q9P2E3|ZNFX1_HUMAN,tr|Q5JXR6|Q5JXR6_HUMAN,tr|Q5JXR7|Q5JXR7_HUMAN,tr|Q5JXR5|Q5JXR5_HUMAN" 4 879.4749 194.59 1752 13296 2 879.475931 440.7447 NFX1-type zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=ZNFX1 PE=2 SV=2 9.76 2949.3 - 3.88E+06 - - - 1.1814 - 1.355 0.227 - 198.1 1 2 0 0.001 7 0 0 0 2.36E+08 1.21E+06 - - - 1.6799 0.9871 230117_WJC_METTL3_WT_vs_EV_F01.13298.13298.2 0.394 14-May R.LFVGSIPK.S "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 859.5167 0.9 1754 13298 2 859.517417 430.7656 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.75 2949.4 - 2.72E+06 - - - 0.7877 - 1.082 0.162 - 78.2 2 2 0 0.0007 8 0 0 0 1.65E+09 1.84E+09 - - - 0.3405 0.9895 230117_WJC_METTL3_WT_vs_EV_F01.13315.13315.2 3.66 12-Jun K.FIPLYSK[136.11].V "sp|Q14694|UBP10_HUMAN,tr|J3KT19|J3KT19_HUMAN,tr|H3BVF1|H3BVF1_HUMAN" 3 874.5044 1.2 1766 13315 2 874.504306 438.2595 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.59 2951.4 - 656341 - - - -0.0972 - 1.102 0.19 - 93.6 1 2 0 -0.0001 7 0 0 0 1.32E+08 1.09E+08 - - - 0.7521 0.996 230117_WJC_METTL3_WT_vs_EV_F01.13323.13323.2 0.271 14-Aug K.LLTLVSTR[166.11].D "sp|Q9NRL2|BAZ1A_HUMAN,tr|A0A087WWN7|A0A087WWN7_HUMAN" 2 911.5679 0.82 1772 13323 2 911.568773 456.7912 Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2 9.75 2952.2 - 1.03E+06 - - - 0.9171 - 1.585 0.1 - 133.2 1 2 0 0.0008 8 0 0 0 7.27E+07 8.86E+07 - - - 1.1684 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.13333.13333.2 0.000765 12-Jul K.YGVDLIR.Y sp|Q6UXN9|WDR82_HUMAN 1 834.46 1.37 1777 13333 2 834.460267 418.2373 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 5.84 2953.5 - 1.75E+06 - - - 0.3763 - 1.385 0.231 - 171.5 1 2 0 0.0003 7 0 0 0 9.45E+07 6.92E+07 - - - 1.7791 0.996 230117_WJC_METTL3_WT_vs_EV_F01.13341.13341.2 0.698 12-Aug K.SVIISIK.G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 758.4902 1.2 1780 13341 2 758.491088 380.2524 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2954.5 - 1.13E+06 - - - 1.1826 - 1.476 0.119 - 248.8 1 2 0 0.0009 7 0 0 0 2.17E+08 1.80E+08 - - - 1.1533 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.13347.13347.2 1.77 18-Dec R.LLAEPVPGIK[136.11].A "sp|P61088|UBE2N_HUMAN,sp|Q5JXB2|UE2NL_HUMAN,tr|F8VZ29|F8VZ29_HUMAN,tr|F8VSD4|F8VSD4_HUMAN,tr|F8VV71|F8VV71_HUMAN" 5 1043.647 1.66 1784 13347 2 1043.647989 522.8308 Ubiquitin-conjugating enzyme E2 N OS=Homo sapiens OX=9606 GN=UBE2N PE=1 SV=1 6 2955.2 - 1.06E+06 - - - 0.917 - 1.819 0.277 - 374.3 1 2 0 0.001 10 0 0 0 1.46E+08 8.82E+07 - - - 2.7566 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.13349.13349.2 1.33 12-Jul K.SVIISIK[136.11].G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 766.5044 1.2 1785 13349 2 766.504877 384.2595 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2955.5 - 2.88E+06 - - - 0.634 - 1.462 0.168 - 195.8 1 2 0 0.0005 7 0 0 0 2.17E+08 1.80E+08 - - - 1.4851 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.13352.13352.2 0.00889 14-Aug R.IFTNLYGR.H "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 4 982.5236 1.12 1788 13352 2 982.522836 492.2691 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.75 2955.8 - 430430 - - - -0.7939 - 1.641 0.338 - 188.7 1 2 0 -0.0008 8 0 0 0 7.29E+07 6.51E+07 - - - 3.031 0.9742 230117_WJC_METTL3_WT_vs_EV_F01.13368.13368.2 1.2 22-Jun R.LLLGPAGGGVPK.L sp|Q96SL8|FIZ1_HUMAN 1 1077.6546 1.23 1795 13368 2 1077.657486 539.8346 Flt3-interacting zinc finger protein 1 OS=Homo sapiens OX=9606 GN=FIZ1 PE=1 SV=2 8.75 2957.8 - 212757 - - - 2.6502 - 1.24 0.095 - 54.1 3 2 0 0.0029 12 0 0 0 1.24E+07 1.01E+07 - - - 0.0946 0.9753 230117_WJC_METTL3_WT_vs_EV_F01.13369.13369.2 6.52 14-Jul K.NLILAGVK.G "sp|Q9UBE0|SAE1_HUMAN,tr|B3KNJ4|B3KNJ4_HUMAN,tr|M0QZS6|M0QZS6_HUMAN,tr|A0A590UKC5|A0A590UKC5_HUMAN,tr|M0QX65|M0QX65_HUMAN,tr|A0A590UKA0|A0A590UKA0_HUMAN,tr|A0A590UK93|A0A590UK93_HUMAN" 7 826.5276 5.4 1796 13369 2 826.527313 414.2711 SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1 PE=1 SV=1 8.75 2957.9 - 1.39E+06 - - - -0.3944 - 1.172 0.101 - 152.2 1 2 0 -0.0003 8 0 0 0 5.64E+07 1.04E+07 - - - 0.2656 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.13370.13370.2 0.675 12-Jul K.IVVLLQR.L "sp|Q06323|PSME1_HUMAN,tr|H0YLU2|H0YLU2_HUMAN" 2 839.5593 1.3 1797 13370 2 839.559438 420.7869 Proteasome activator complex subunit 1 OS=Homo sapiens OX=9606 GN=PSME1 PE=1 SV=1 9.75 2958 - 776767 - - - 0.1965 - 1.526 0.285 - 108.5 1 2 0 0.0002 7 0 0 0 3.62E+07 2.79E+07 - - - 2.4851 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.13373.13373.2 0.574 14-Jul R.ILEVLPGR.R sp|Q9UI43|MRM2_HUMAN 1 895.5491 2.86 1798 13373 2 895.549049 448.7818 "rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1" 6 2958.4 - 744704 - - - -0.0592 - 1.475 0.165 - 115.6 1 2 0 -0.0001 8 0 0 0 6.66E+07 2.33E+07 - - - 1.4318 0.999 230117_WJC_METTL3_WT_vs_EV_F01.13375.13375.2 0.25 14-Sep R.LLAAFEER.E "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 947.5076 1.29 1799 13375 2 947.508073 474.7611 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.53 2958.6 - 1.38E+06 - - - 0.4654 - 1.706 0.266 - 243.4 1 2 0 0.0004 8 0 0 0 1.66E+08 1.29E+08 - - - 2.6165 0.9854 230117_WJC_METTL3_WT_vs_EV_F01.13384.13384.2 0.0857 12-Jun K.ELVVLPR[166.11].E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 834.5203 0.51 1804 13384 2 834.520005 418.2674 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2959.7 - 2.65E+06 - - - -0.3044 - 1.176 0.141 - 165.2 1 2 0 -0.0003 7 0 0 0 1.96E+08 3.86E+08 - - - 0.596 0.9921 230117_WJC_METTL3_WT_vs_EV_F01.13385.13385.2 2.68 14-Jun K.LVALNLDR.L "sp|Q9Y3D3|RT16_HUMAN,tr|A6ND22|A6ND22_HUMAN" 2 912.5393 1.14 1805 13385 2 912.540019 457.2769 "28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1" 5.84 2959.8 - 954607 - - - 0.8252 - 1.457 0.068 - 96.1 1 2 0 0.0008 8 0 0 0 8.88E+07 7.79E+07 - - - 0.6782 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.13387.13387.2 0.000253 16-Sep R.EMGVIAAMR.D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 976.4834 2.32 1807 13387 2 976.489356 489.249 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 6.1 2960 - 118893 - - - 6.0923 - 1.729 0.452 - 197.6 1 2 0 0.0059 9 0 0 0 2.24E+07 9.65E+06 - - - 3.9617 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.13389.13389.2 0.018 14-Sep R.LLAAFEER[166.11].E "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 957.5159 1.28 1808 13389 2 957.516193 479.7652 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.53 2960.2 - 2.32E+06 - - - 0.3039 - 1.807 0.304 - 292.3 1 2 0 0.0003 8 0 0 0 1.67E+08 1.31E+08 - - - 3.0707 0.999 230117_WJC_METTL3_WT_vs_EV_F01.13393.13393.2 0.08 14-Aug R.ILEVLPGR[166.11].R sp|Q9UI43|MRM2_HUMAN 1 905.5574 2.87 1810 13393 2 905.558767 453.786 "rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1" 6 2960.6 - 807242 - - - 1.5405 - 1.593 0.258 - 145.5 1 2 0 0.0014 8 0 0 0 6.67E+07 2.33E+07 - - - 2.3504 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.13395.13395.2 0.0471 14-Jul R.IFTNLYGR[166.11].H "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 4 992.5319 1.12 1811 13395 2 992.532478 497.2732 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.75 2960.9 - 1.71E+06 - - - 0.5965 - 1.495 0.258 - 159.8 1 2 0 0.0006 8 0 0 0 7.29E+07 6.52E+07 - - - 2.1592 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.13396.13396.2 0.0053 16-Nov K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 80.83 1812 13396 2 1059.55722 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2961 - 413458 - - - 1.1156 - 1.922 0.376 - 429.3 1 2 0 0.0012 9 0 0 0 2.61E+07 3.23E+05 - - - 3.708 1 230117_WJC_METTL3_WT_vs_EV_F01.13397.13397.2 1.56E-08 24-Nov R.TTPSYVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1486.694 14.5 1813 13397 2 1486.69493 744.3543 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2961.1 - 498615 - - - 0.6329 - 2.517 0.584 - 393.9 1 2 0 0.0009 13 0 0 0 7.08E+07 4.88E+06 - - - 5.7232 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.13402.13402.2 0.078 12-Aug R.IGLLDPR[166.11].W "sp|Q15459|SF3A1_HUMAN,tr|H7C1L2|H7C1L2_HUMAN" 2 792.4733 1.39 1815 13402 2 792.473503 397.2439 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 5.84 2961.8 - 4.44E+06 - - - 0.2461 - 1.657 0.155 - 130.5 1 2 0 0.0002 7 0 0 0 3.76E+08 2.72E+08 - - - 1.7859 0.9852 230117_WJC_METTL3_WT_vs_EV_F01.13404.13404.2 1.58 12-Jul K.TIADIIR.T "sp|P49368|TCPG_HUMAN,sp|Q16878|CDO1_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 800.4756 10.66 1816 13404 2 800.476188 401.2451 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.5 2962 - 4.45E+07 - - - 0.7308 - 1.461 0.002 - 169.7 1 2 0 0.0006 7 0 0 0 2.36E+09 2.21E+08 - - - 0.2569 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.13416.13416.2 0.00373 18-Sep R.AFGSLGPGLR.L "sp|Q96JG8|MAGD4_HUMAN,tr|D6RBW3|D6RBW3_HUMAN,tr|A0A804HHZ9|A0A804HHZ9_HUMAN" 3 973.5345 14.01 1820 13416 2 973.537007 487.7745 Melanoma-associated antigen D4 OS=Homo sapiens OX=9606 GN=MAGED4 PE=1 SV=3 9.79 2963.7 - 567512 - - - 2.5597 - 1.464 0.34 - 231.3 1 2 0 0.0025 10 0 0 0 1.91E+07 1.36E+06 - - - 2.6154 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.13419.13419.2 1.01 14-Jul K.LVALNLDR[166.11].L "sp|Q9Y3D3|RT16_HUMAN,tr|A6ND22|A6ND22_HUMAN" 2 922.5475 1.14 1823 13419 2 922.548439 462.281 "28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1" 5.84 2964 - 2.49E+06 - - - 0.9788 - 1.315 0.214 - 150.2 2 2 0 0.0009 8 0 0 0 8.89E+07 7.79E+07 - - - 1.3127 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.13420.13420.2 0.0596 14-Jul K.VMMVALGR.S sp|Q9UKD2|MRT4_HUMAN 1 875.4721 0.91 1824 13420 2 875.473006 438.7433 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 9.72 2964 - 1.21E+06 - - - 1.0189 - 1.254 0.251 - 114.8 1 2 0 0.0009 8 0 0 0 6.54E+07 7.18E+07 - - - 1.5772 0.997 230117_WJC_METTL3_WT_vs_EV_F01.13421.13421.2 0.0859 12-Jun K.YVIYIER[166.11].V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 964.5257 0.83 1825 13421 2 964.5263 483.2701 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 6 2964.2 - 319730 - - - 0.5827 - 1.28 0.225 - 122.7 1 2 0 0.0006 7 0 0 0 8.95E+08 1.07E+09 - - - 1.4849 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.13425.13425.2 0.112 12-Jun K.ELVVLPR.E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 824.512 0.51 1827 13425 2 824.51281 413.2633 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2964.7 - 2.45E+06 - - - 0.9957 - 1.408 0.251 - 211.4 1 2 0 0.0008 7 0 0 0 1.96E+08 3.86E+08 - - - 1.9788 1 230117_WJC_METTL3_WT_vs_EV_F01.13426.13426.2 2.63E-06 24-Sep R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 14.46 1828 13426 2 1496.705961 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2964.8 - 122800 - - - 2.4734 - 2.157 0.561 - 226 1 2 0 0.0037 13 0 0 0 7.06E+07 4.88E+06 - - - 5.1563 0.9881 230117_WJC_METTL3_WT_vs_EV_F01.13429.13429.2 0.0195 18-Aug R.VAQLEQVYIR.G sp|P62318|SMD3_HUMAN 1 1217.6768 0.94 1829 13429 2 1217.679458 609.8457 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.97 2965.2 - 197728 - - - 2.1648 - 1.48 0.045 - 181.4 1 2 0 0.0026 10 0 0 0 4.53E+06 4.83E+06 - - - 0.4669 0.9618 230117_WJC_METTL3_WT_vs_EV_F01.13432.13432.2 7.17 14-Jul K.LLIIGPQK.T "sp|P52848|NDST1_HUMAN,tr|E7EVJ3|E7EVJ3_HUMAN" 2 880.5746 0.96 1830 13432 2 880.573621 441.2946 Bifunctional heparan sulfate N-deacetylase\N-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=NDST1 PE=1 SV=1 8.75 2965.6 - 356278 - - - -1.0993 - 1.251 0.074 - 100.4 1 2 0 -0.001 8 0 0 0 1.85E+07 1.92E+07 - - - 0.2627 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.13435.13435.2 0.883 16-Sep R.ILVGTNLVR[166.11].L sp|Q96QK1|VPS35_HUMAN 1 993.621 1.87 1831 13435 2 993.623124 497.8178 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 9.75 2966 - 876506 - - - 2.1024 - 1.69 0.145 - 198.4 1 2 0 0.0021 9 0 0 0 7.78E+07 4.17E+07 - - - 1.6294 0.9919 230117_WJC_METTL3_WT_vs_EV_F01.13437.13437.2 6.28 12-Jul K.LLDIVAR.S sp|Q12931|TRAP1_HUMAN 1 798.4963 2.27 1832 13437 2 798.497658 400.2554 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.84 2966.2 - 6.59E+06 - - - 1.6519 - 1.474 0.05 - 144.3 1 2 0 0.0013 7 0 0 0 3.15E+08 1.38E+08 - - - 0.6392 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.13438.13438.2 0.585 14-Sep R.LGALALPR[166.11].G "sp|Q6SPF0|SAMD1_HUMAN,tr|E9PIW9|E9PIW9_HUMAN" 2 819.5206 2.12 1833 13438 2 819.521673 410.7676 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.75 2966.3 - 1.20E+06 - - - 1.3178 - 2.04 0.204 - 283.7 1 2 0 0.0011 8 0 0 0 2.16E+08 1.02E+08 - - - 2.6976 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.13442.13442.2 0.000133 24-Oct K.VIDPATATSVDLR.D sp|P50991|TCPD_HUMAN 1 1356.7249 999 1835 13442 2 1356.728008 679.3697 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 2966.9 - 184257 - - - 2.2945 - 1.842 0.432 - 184 1 2 0 0.0031 13 0 0 0 9.50E+06 0.00E+00 - - - 3.7985 0.972 230117_WJC_METTL3_WT_vs_EV_F01.13443.13443.2 0.0362 22-Jul R.LLSASPVDAAIR[166.11].V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1221.6957 4.2 1836 13443 2 1221.702968 611.8551 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 5.84 2967 - 128891 - - - 5.9843 - 1.466 0.239 - 98.7 2 2 0 0.0073 12 0 0 0 7.50E+06 1.78E+06 - - - 1.676 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.13444.13444.2 0.745 12-Aug K.YVIYIER.V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 954.5175 0.83 1837 13444 2 954.519308 478.266 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 6 2967 - 2.66E+06 - - - 1.9277 - 1.699 0.264 - 280.8 1 2 0 0.0018 7 0 0 0 8.96E+08 1.07E+09 - - - 2.6698 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.13445.13445.2 0.14 16-Aug R.ILVGTNLVR.L sp|Q96QK1|VPS35_HUMAN 1 983.6128 1.87 1838 13445 2 983.614662 492.8137 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 9.75 2967.1 - 2.20E+06 - - - 1.9286 - 1.673 0.16 - 160.7 1 2 0 0.0019 9 0 0 0 7.78E+07 4.17E+07 - - - 1.711 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.13453.13453.2 0.000216 16-Jun K.ESYSIYVYK[136.11].V "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q6DN03|H2B2C_HUMAN,sp|P23527|H2B1O_HUMAN,sp|Q6DRA6|H2B2D_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN" 7 1158.5688 0.68 1842 13453 2 1158.57419 580.2917 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.1 2968.1 - 143800 - - - 4.6169 - 1.497 0.458 - 76.8 1 2 0 0.0053 9 0 0 0 1.80E+06 2.65E+06 - - - 3.5893 0.9962 230117_WJC_METTL3_WT_vs_EV_F01.13467.13467.2 0.0665 12-Jun R.VVFQEFR[166.11].Q sp|P35579|MYH9_HUMAN 1 933.4948 0.92 1851 13467 2 933.498219 467.7547 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2969.8 - 269485 - - - 3.6926 - 1.199 0.334 - 142.8 1 2 0 0.0034 7 0 0 0 2.59E+08 2.80E+08 - - - 2.0819 0.9481 230117_WJC_METTL3_WT_vs_EV_F01.13470.13470.2 2.89 16-Jun K.LPPLPAVER.V "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 990.5862 1.09 1852 13470 2 990.588762 496.3004 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6 2970.2 - 2.12E+06 - - - 2.5702 - 1.336 0.005 - 119.7 5 2 0 0.0025 9 0 0 0 1.90E+08 1.75E+08 - - - -0.397 0.9279 230117_WJC_METTL3_WT_vs_EV_F01.13491.13491.2 4.29 12-May K.LPVPGYN.- sp|Q9Y6N1|COX11_HUMAN 1 758.3963 - 1865 13491 2 758.39652 380.2054 "Cytochrome c oxidase assembly protein COX11, mitochondrial OS=Homo sapiens OX=9606 GN=COX11 PE=1 SV=3" 5.52 2972.9 - 313436 - - - 0.3033 - 1.004 0.082 - 57 6 2 0 0.0002 7 0 0 0 - - - - - -0.6884 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.13496.13496.2 0.152 12-Jun R.EALGLLR.A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 770.465 1.1 1868 13496 2 770.466129 386.2398 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2973.4 - 1.35E+06 - - - 1.416 - 1.486 0.164 - 144.3 1 2 0 0.0011 7 0 0 0 2.65E+08 2.40E+08 - - - 1.507 0.997 230117_WJC_METTL3_WT_vs_EV_F01.13498.13498.2 0.0372 20-Jun K.QAGVFEPTIVK.V "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1187.655 31.8 1870 13498 2 1187.657181 594.8348 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2973.6 - 118549 - - - 1.8162 - 1.268 0.235 - 80 1 2 0 0.0022 11 0 0 0 1.86E+07 5.83E+05 - - - 1.4184 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.13502.13502.2 0.429 14-Aug R.LLSTYLER[166.11].Y "sp|Q12769|NU160_HUMAN,tr|G3V198|G3V198_HUMAN" 2 1003.5578 1.16 1872 13502 2 1003.561698 502.7862 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 6 2974.1 - 1.79E+06 - - - 3.9181 - 1.609 0.244 - 172.4 1 2 0 0.0039 8 0 0 0 6.26E+07 5.41E+07 - - - 2.2764 0.9652 230117_WJC_METTL3_WT_vs_EV_F01.13503.13503.2 2.49 12-May K.VLLDQLR.F "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 855.5178 1.43 1873 13503 2 855.520541 428.7662 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 5.81 2974.2 - 1.33E+06 - - - 3.2016 - 1.131 0.11 - 63.4 2 2 0 0.0027 7 0 0 0 3.20E+08 2.23E+08 - - - 0.1082 0.989 230117_WJC_METTL3_WT_vs_EV_F01.13504.13504.2 0.00094 16-Oct K.LLNYAPLEK.- sp|P62875|RPAB5_HUMAN 1 1059.5964 1.2 1874 13504 2 1059.603877 530.8055 "DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1" 6 2974.3 - 485629 - - - 7.0121 - 1.802 0.371 - 260.6 1 2 0 0.0074 9 0 0 0 2.30E+07 1.91E+07 - - - 3.4826 0.998 230117_WJC_METTL3_WT_vs_EV_F01.13509.13509.2 0.722 12-Jun R.EALGLLR[166.11].A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 780.4733 1.1 1877 13509 2 780.474102 391.2439 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2975 - 4.37E+06 - - - 1.0173 - 1.67 0.147 - 146.3 1 2 0 0.0008 7 0 0 0 2.64E+08 2.40E+08 - - - 1.7514 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.13510.13510.2 0.0517 12-Jun R.YLLAMER.H "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 894.4633 3.05 1878 13510 2 894.464014 448.2389 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 2975.1 - 781537 - - - 0.7714 - 1.313 0.159 - 123.9 1 2 0 0.0007 7 0 0 0 4.24E+07 1.39E+07 - - - 1.078 0.8587 230117_WJC_METTL3_WT_vs_EV_F01.13511.13511.2 0.0712 12-Jul P.FPAALLR.V "sp|Q9H0D2|ZN541_HUMAN,sp|Q9UJV9|DDX41_HUMAN,tr|H7BXG6|H7BXG6_HUMAN,tr|M0R167|M0R167_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|A0A075B6F0|A0A075B6F0_HUMAN,tr|H0Y8L8|H0Y8L8_HUMAN" 7 786.4752 1.08 1879 13511 2 786.476777 394.2449 Zinc finger protein 541 OS=Homo sapiens OX=9606 GN=ZNF541 PE=1 SV=3 9.75 2975.2 - 1.29E+06 - - - 1.9937 - 1.396 0.228 - 160.9 1 1 0 0.0016 7 0 0 0 4.69E+08 4.35E+08 - - - 1.7816 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.13515.13515.2 0.111 16-Sep R.IVDPEIALK.L "sp|P33240|CSTF2_HUMAN,tr|A0A0A0MT56|A0A0A0MT56_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 996.5855 1.46 1881 13515 2 996.586939 499.3001 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.37 2975.7 - 2.16E+06 - - - 1.3958 - 1.786 0.332 - 162.9 1 2 0 0.0014 9 0 0 0 5.13E+08 3.50E+08 - - - 3.1706 0.9742 230117_WJC_METTL3_WT_vs_EV_F01.13519.13519.2 0.502 16-Jul R.IVDPEIALK[136.11].L "sp|P33240|CSTF2_HUMAN,tr|A0A0A0MT56|A0A0A0MT56_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 1004.5997 2.43 1882 13519 2 1004.596984 503.3072 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.37 2976.3 - 1.73E+06 - - - -2.7513 - 1.25 0.222 - 80 1 2 0 -0.0028 9 0 0 0 8.57E+08 3.52E+08 - - - 1.3254 0.9882 230117_WJC_METTL3_WT_vs_EV_F01.13520.13520.2 0.765 12-Jun K.VFFASVR.S "sp|Q9UKE5|TNIK_HUMAN,sp|O95819|M4K4_HUMAN,sp|Q8N4C8|MINK1_HUMAN,tr|A0A0D9SEY1|A0A0D9SEY1_HUMAN,tr|C9J840|C9J840_HUMAN,tr|E7EX83|E7EX83_HUMAN,tr|E7EN19|E7EN19_HUMAN,tr|H7C360|H7C360_HUMAN,tr|A0A0D9SG62|A0A0D9SG62_HUMAN,tr|G3XAA2|G3XAA2_HUMAN,tr|E7ENQ1|E7ENQ1_HUMAN,tr|H7C0P6|H7C0P6_HUMAN,tr|G5E948|G5E948_HUMAN" 13 824.4545 0.24 1883 13520 2 824.456011 413.2345 TRAF2 and NCK-interacting protein kinase OS=Homo sapiens OX=9606 GN=TNIK PE=1 SV=1 9.72 2976.3 - 1.02E+06 - - - 1.8643 - 1.16 0.121 - 116.8 1 2 0 0.0015 7 0 0 0 3.31E+07 1.36E+08 - - - 0.4045 0.9893 230117_WJC_METTL3_WT_vs_EV_F01.13521.13521.2 0.109 12-Jul R.LMFAVEK[136.11].S sp|Q5SWX8|ODR4_HUMAN 1 844.4608 0.86 1884 13521 2 844.45959 423.2377 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 6 2976.4 - 704208 - - - -1.4459 - 1.418 0.167 - 103.3 1 2 0 -0.0012 7 0 0 0 6.80E+07 7.87E+07 - - - 1.3807 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.13538.13538.2 0.0722 14-Oct R.IGVAILQR.S "sp|Q68CQ4|UTP25_HUMAN,tr|H7C2R4|H7C2R4_HUMAN" 2 868.5494 0.34 1893 13538 2 868.550729 435.282 U3 small nucleolar RNA-associated protein 25 homolog OS=Homo sapiens OX=9606 GN=UTP25 PE=1 SV=2 9.75 2978.5 - 506604 - - - 1.4875 - 1.753 0.237 - 263.4 1 2 0 0.0013 8 0 0 0 6.83E+06 2.03E+07 - - - 2.484 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.13542.13542.2 0.315 12-Jun K.VLLDQLR[166.11].F "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 865.5261 1.57 1895 13542 2 865.526655 433.7703 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 5.81 2978.9 - 5.23E+06 - - - 0.6736 - 1.358 0.179 - 104.9 1 2 0 0.0006 7 0 0 0 3.18E+08 2.03E+08 - - - 1.3325 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.13543.13543.2 0.0009 16-Sep K.VVLLTEVDK[136.11].L sp|P40938|RFC3_HUMAN 1 1022.6103 1.75 1896 13543 2 1022.611146 512.3124 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 4.37 2979 - 457596 - - - 0.8156 - 1.679 0.41 - 250.2 1 2 0 0.0008 9 0 0 0 5.44E+07 3.10E+07 - - - 3.5682 0.9705 230117_WJC_METTL3_WT_vs_EV_F01.13547.13547.2 0.155 12-Sep K.PSVYFIK[136.11].F "sp|Q99865|SPI2A_HUMAN,sp|Q56A73|SPIN4_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 9 860.4887 0.5 1897 13547 2 860.489009 431.2516 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 9.01 2979.6 - 9.53E+06 - - - 0.3115 - 2.029 0.381 - 245.1 1 1 0 0.0003 7 0 0 0 3.41E+08 6.78E+08 - - - 4.0969 0.9051 230117_WJC_METTL3_WT_vs_EV_F01.13551.13551.2 1.22 20-May R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 999 1899 13551 2 1068.658706 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 2980.1 - 995317 - - - 4.1267 - 1.269 0.06 - 43.5 5 2 0 0.0044 11 0 0 0 7.13E+07 0.00E+00 - - - -0.185 0.9738 230117_WJC_METTL3_WT_vs_EV_F01.13552.13552.2 1.94 12-Aug K.QLLYLEK.Y "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 3 905.5222 0.7 1900 13552 2 905.521837 453.7684 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 6 2980.2 - 1.90E+06 - - - -0.4219 - 1.23 0.073 - 209.5 1 2 0 -0.0004 7 0 0 0 9.82E+07 1.41E+08 - - - 0.236 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.13562.13562.2 0.03 12-Aug R.VVFQEFR.Q sp|P35579|MYH9_HUMAN 1 923.4865 0.92 1905 13562 2 923.486894 462.7505 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2981.4 - 3.24E+06 - - - 0.4245 - 1.506 0.385 - 295.9 1 2 0 0.0004 7 0 0 0 2.59E+08 2.81E+08 - - - 3.1819 0.999 230117_WJC_METTL3_WT_vs_EV_F01.13564.13564.2 0.0194 12-Jul R.VVFQEFR.Q sp|P35579|MYH9_HUMAN 1 923.4865 0.92 1907 13564 2 923.486288 462.7505 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2981.6 - 3.24E+06 - - - -0.2317 - 1.468 0.372 - 252 1 2 0 -0.0002 7 0 0 0 2.59E+08 2.81E+08 - - - 3.0049 0.8576 230117_WJC_METTL3_WT_vs_EV_F01.13567.13567.2 0.0622 12-Aug P.FPAALLR[166.11].V "sp|Q9H0D2|ZN541_HUMAN,sp|Q9UJV9|DDX41_HUMAN,tr|H7BXG6|H7BXG6_HUMAN,tr|M0R167|M0R167_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|A0A075B6F0|A0A075B6F0_HUMAN,tr|H0Y8L8|H0Y8L8_HUMAN" 7 796.4835 1.13 1909 13567 2 796.483222 399.249 Zinc finger protein 541 OS=Homo sapiens OX=9606 GN=ZNF541 PE=1 SV=3 9.75 2982 - 3.53E+06 - - - -0.3227 - 1.473 0.264 - 297.8 1 1 0 -0.0003 7 0 0 0 1.91E+08 1.69E+08 - - - 2.218 0.9649 230117_WJC_METTL3_WT_vs_EV_F01.13569.13569.2 0.273 12-Sep K.PSVYFIK.F "sp|Q99865|SPI2A_HUMAN,sp|Q56A73|SPIN4_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 9 852.4745 0.5 1910 13569 2 852.474316 427.2445 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 9.01 2982.2 - 8.36E+06 - - - -0.2639 - 2.065 0.416 - 283.8 1 1 0 -0.0002 7 0 0 0 3.41E+08 6.78E+08 - - - 4.4111 0.9942 230117_WJC_METTL3_WT_vs_EV_F01.13572.13572.2 0.245 12-Jun R.AFLGELK[136.11].T sp|P78527|PRKDC_HUMAN 1 784.4574 0.97 1912 13572 2 784.457163 393.236 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6.05 2982.4 - 4.23E+06 - - - -0.3531 - 1.327 0.187 - 120.1 1 2 0 -0.0003 7 0 0 0 1.42E+08 1.46E+08 - - - 1.3185 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.13575.13575.2 0.0333 12-Jun R.AFLGELK.T sp|P78527|PRKDC_HUMAN 1 776.4432 0.97 1913 13575 2 776.442715 389.2289 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6.05 2982.8 - 4.51E+06 - - - -0.6762 - 1.349 0.324 - 161.9 1 2 0 -0.0005 7 0 0 0 1.41E+08 1.46E+08 - - - 2.3824 1 230117_WJC_METTL3_WT_vs_EV_F01.13585.13585.2 0.000224 16-Nov K.PLYVALAQR[166.11].K "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PIK9|A0A6I8PIK9_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 25 1039.6054 1.15 1917 13585 2 1039.604375 520.81 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.18 2984.2 - 1.19E+06 - - - -0.9715 - 2.275 0.522 - 502.3 1 1 0 -0.001 9 0 0 0 4.62E+08 4.02E+08 - - - 5.2742 0.9831 230117_WJC_METTL3_WT_vs_EV_F01.13600.13600.2 0.183 14-Sep K.IADFGLAR.L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 861.4709 1.95 1925 13600 2 861.466859 431.7427 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2986 - 2.10E+07 - - - -4.6351 - 1.847 0.271 - 196.7 1 2 0 -0.004 8 0 0 0 1.11E+09 5.70E+08 - - - 2.8918 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.13601.13601.2 0.206 14-Jul K.LLQPLVPR[166.11].Y sp|Q8N8A6|DDX51_HUMAN 1 944.6047 1.1 1926 13601 2 944.605414 473.3096 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2986.1 - 867980 - - - 0.8014 - 1.318 0.182 - 126.1 1 2 0 0.0008 8 0 0 0 1.40E+08 1.28E+08 - - - 1.2178 0.9888 230117_WJC_METTL3_WT_vs_EV_F01.13612.13612.2 0.973 14-Aug K.LAVEAVLR.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 869.5335 7.34 1931 13612 2 869.532743 435.774 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 2987.4 - 1.54E+07 - - - -0.8154 - 1.582 0.081 - 218.1 1 2 0 -0.0007 8 0 0 0 6.99E+09 9.53E+08 - - - 1.0224 0.997 230117_WJC_METTL3_WT_vs_EV_F01.13613.13613.2 0.076 16-Jun K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 3.25 1932 13613 2 1014.535815 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 2987.6 - 1.15E+06 - - - 1.2222 - 1.462 0.167 - 70.6 1 2 0 0.0012 9 0 0 0 5.85E+07 1.80E+07 - - - 1.3729 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.13625.13625.2 0.788 14-Aug K.LLQLVEDR.G "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 984.5604 0.67 1939 13625 2 984.559669 493.2875 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 2988.9 - 4.81E+06 - - - -0.7374 - 1.566 0.219 - 156 1 2 0 -0.0007 8 0 0 0 1.64E+08 2.44E+08 - - - 2.011 0.9336 230117_WJC_METTL3_WT_vs_EV_F01.13626.13626.2 2.41 12-Jul R.YFEPLVK.K "sp|Q7L590|MCM10_HUMAN,tr|Q5T670|Q5T670_HUMAN" 2 894.4851 4.51 1940 13626 2 894.483621 448.2498 Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2 6 2989 - 1.36E+06 - - - -1.6591 - 1.081 0.112 - 135.8 1 2 0 -0.0015 7 0 0 0 1.38E+08 3.06E+07 - - - 0.1146 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.13639.13639.2 0.0316 14-Sep K.IINDLLAR.S "sp|P51530|DNA2_HUMAN,tr|F8VR31|F8VR31_HUMAN,tr|H0Y455|H0Y455_HUMAN" 3 926.5549 3.14 1944 13639 2 926.555576 464.2847 DNA replication ATP-dependent helicase\nuclease DNA2 OS=Homo sapiens OX=9606 GN=DNA2 PE=1 SV=3 5.84 2990.9 - 273645 - - - 0.7123 - 1.609 0.298 - 176.6 1 2 0 0.0007 8 0 0 0 3.72E+07 1.18E+07 - - - 2.6762 0.984 230117_WJC_METTL3_WT_vs_EV_F01.13645.13645.2 0.0449 14-Jul R.LLAFAEAR.A "sp|Q8WUY8|NAT14_HUMAN,sp|Q99519|NEUR1_HUMAN,tr|M0R1E3|M0R1E3_HUMAN,tr|E9PIF4|E9PIF4_HUMAN" 4 889.5022 2.1 1946 13645 2 889.498177 445.7584 Probable N-acetyltransferase 14 OS=Homo sapiens OX=9606 GN=NAT14 PE=1 SV=1 6 2991.7 - 2.76E+06 - - - -4.4688 - 1.614 0.318 - 113.5 1 2 0 -0.004 8 0 0 0 7.61E+07 3.63E+07 - - - 2.8323 0.9936 230117_WJC_METTL3_WT_vs_EV_F01.13652.13652.2 0.219 12-Aug K.ILEVDLK[136.11].N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 836.5099 0.88 1950 13652 2 836.50904 419.2622 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2992.5 - 3.58E+06 - - - -0.9922 - 1.513 0.164 - 171.2 1 2 0 -0.0008 7 0 0 0 3.33E+08 3.77E+08 - - - 1.5641 0.9812 230117_WJC_METTL3_WT_vs_EV_F01.13662.13662.2 2.66 12-May R.IINTFLK.T "sp|Q86Y56|DAAF5_HUMAN,tr|H0Y650|H0Y650_HUMAN,tr|E9PGY2|E9PGY2_HUMAN" 3 847.5167 12.77 1954 13662 2 847.516526 424.7656 Dynein axonemal assembly factor 5 OS=Homo sapiens OX=9606 GN=DNAAF5 PE=1 SV=4 8.75 2993.8 - 858539 - - - -0.2525 - 1.255 0.144 - 51.1 9 2 0 -0.0002 7 0 0 0 5.03E+07 3.94E+06 - - - 0.3979 0.9926 230117_WJC_METTL3_WT_vs_EV_F01.13667.13667.2 0.0253 14-Jul K.LLQPLVPR.Y sp|Q8N8A6|DDX51_HUMAN 1 934.5964 1.09 1956 13667 2 934.594314 468.3055 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2994.4 - 3.87E+06 - - - -2.2181 - 1.38 0.289 - 205.3 1 2 0 -0.0021 8 0 0 0 1.40E+08 1.28E+08 - - - 2.1463 0.9901 230117_WJC_METTL3_WT_vs_EV_F01.13670.13670.2 0.927 12-Jun R.YLDELMK.L "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 910.447 1.93 1957 13670 2 910.447578 456.2308 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 2994.8 - 1.02E+06 - - - 0.6294 - 1.055 0.183 - 103.2 1 2 0 0.0006 7 0 0 0 5.94E+07 3.08E+07 - - - 0.5621 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.13675.13675.2 0.0886 14-Aug K.ILDVMYSR[166.11].L sp|P78527|PRKDC_HUMAN 1 1005.5193 0.97 1959 13675 2 1005.521099 503.7669 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2995.6 - 635697 - - - 1.817 - 1.524 0.332 - 138 1 2 0 0.0018 8 0 0 0 7.57E+07 7.83E+07 - - - 2.7633 0.9923 230117_WJC_METTL3_WT_vs_EV_F01.13681.13681.2 0.126 14-Sep R.LLAFAEAR[166.11].A "sp|Q8WUY8|NAT14_HUMAN,sp|Q99519|NEUR1_HUMAN,tr|M0R1E3|M0R1E3_HUMAN,tr|E9PIF4|E9PIF4_HUMAN" 4 899.5104 2.09 1960 13681 2 899.507634 450.7625 Probable N-acetyltransferase 14 OS=Homo sapiens OX=9606 GN=NAT14 PE=1 SV=1 6 2996.5 - 454714 - - - -3.0995 - 1.847 0.244 - 238.3 1 2 0 -0.0028 8 0 0 0 7.57E+07 3.62E+07 - - - 2.6928 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.13697.13697.2 0.00431 18-Sep K.QQLLIGAYAK.A sp|Q99832|TCPH_HUMAN 1 1103.6339 13.35 1969 13697 2 1103.633245 552.8242 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.59 2998.3 - 415248 - - - -0.589 - 1.483 0.375 - 190.9 1 2 0 -0.0006 10 0 0 0 9.59E+06 7.18E+05 - - - 2.9105 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.13698.13698.2 0.255 12-Jul K.ILEVDLK.N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 828.4957 0.88 1970 13698 2 828.496398 415.2551 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2998.3 - 6.79E+06 - - - 0.8787 - 1.504 0.164 - 148.5 1 2 0 0.0007 7 0 0 0 3.33E+08 3.77E+08 - - - 1.5453 0.9947 230117_WJC_METTL3_WT_vs_EV_F01.13706.13706.2 0.0142 14-Aug R.DLAPIGIR.V "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 853.5022 0.98 1974 13706 2 853.50384 427.7584 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 5.84 2999.3 - 4.67E+06 - - - 1.9777 - 1.464 0.11 - 274.3 1 2 0 0.0017 8 0 0 0 2.54E+08 2.58E+08 - - - 1.0025 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.13707.13707.2 0.142 12-Jun K.EAVLLLK[136.11].K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 792.52 0.75 1975 13707 2 792.520886 397.2673 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 2999.4 - 2.38E+06 - - - 1.0662 - 1.421 0.233 - 130.1 1 2 0 0.0008 7 0 0 0 6.50E+08 8.68E+08 - - - 1.875 0.981 230117_WJC_METTL3_WT_vs_EV_F01.13708.13708.2 2.38 12-May R.YLDELMK[136.11].L "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 918.4612 1.92 1976 13708 2 918.461291 460.2379 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 2999.4 - 630012 - - - 0.0936 - 1.096 0.126 - 75.5 1 2 0 0.0001 7 0 0 0 5.96E+07 3.11E+07 - - - 0.2621 0.9938 230117_WJC_METTL3_WT_vs_EV_F01.13716.13716.2 0.577 12-Jun K.EAVLLLK.K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 784.5058 0.75 1981 13716 2 784.506753 393.2602 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 3000.3 - 2.89E+06 - - - 1.1625 - 1.354 0.111 - 161.3 1 2 0 0.0009 7 0 0 0 6.50E+08 8.68E+08 - - - 0.8208 0.9767 230117_WJC_METTL3_WT_vs_EV_F01.13717.13717.2 2.01 12-Jun K.VLEILGK.K "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 10 770.4902 2.47 1982 13717 2 770.493394 386.2524 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.97 3000.4 - 1.11E+06 - - - 4.1571 - 1.385 0.179 - 110.4 18 2 0 0.0032 7 0 0 0 5.09E+07 2.06E+07 - - - 0.8334 0.996 230117_WJC_METTL3_WT_vs_EV_F01.13721.13721.2 1.33 12-Jul K.VLEILGK[136.11].K "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 10 778.5044 2.57 1984 13721 2 778.505586 390.2595 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.97 3001 - 641458 - - - 1.535 - 1.43 0.161 - 95.3 3 2 0 0.0012 7 0 0 0 5.37E+07 2.09E+07 - - - 1.15 0.8781 230117_WJC_METTL3_WT_vs_EV_F01.13730.13730.2 0.703 14-Jul A.PSPGHILR.V "sp|Q63HM2|PCX4_HUMAN,tr|B5MC47|B5MC47_HUMAN,tr|H0YIY3|H0YIY3_HUMAN,tr|B6ZDM2|B6ZDM2_HUMAN" 4 875.4977 6.75 1990 13730 2 875.498507 438.7561 Pecanex-like protein 4 OS=Homo sapiens OX=9606 GN=PCNX4 PE=1 SV=4 10.18 3002 - 1.58E+06 - - - 0.8806 - 1.447 0.234 - 157.3 1 1 0 0.0008 8 0 0 0 6.62E+07 9.81E+06 - - - 1.8835 0.9058 230117_WJC_METTL3_WT_vs_EV_F01.13734.13734.2 0.000791 18-Nov T.LGSATALMIR[166.11].E "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 1041.588 1.02 1992 13734 2 1041.592228 521.8013 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3002.5 - 359487 - - - 4.039 - 2.063 0.362 - 236.1 1 1 0 0.0042 10 0 0 0 2.13E+07 2.09E+07 - - - 3.7348 0.999 230117_WJC_METTL3_WT_vs_EV_F01.13745.13745.2 0.00522 14-Sep K.ILDVMYSR.L sp|P78527|PRKDC_HUMAN 1 995.511 0.97 1998 13745 2 995.510246 498.7628 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 3003.8 - 1.69E+06 - - - -0.7594 - 1.74 0.381 - 238.6 1 2 0 -0.0008 8 0 0 0 7.57E+07 7.80E+07 - - - 3.5253 0.9936 230117_WJC_METTL3_WT_vs_EV_F01.13751.13751.2 1.97 12-Aug R.LLQIIER[166.11].Y sp|P78527|PRKDC_HUMAN 1 893.5574 1.16 2002 13751 2 893.558757 447.786 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 3004.5 - 2.73E+06 - - - 1.55 - 1.579 0.042 - 244.2 1 2 0 0.0014 7 0 0 0 2.72E+08 2.34E+08 - - - 0.7981 0.9919 230117_WJC_METTL3_WT_vs_EV_F01.13760.13760.2 1.04 18-Aug R.AVLGPVPLTR.T sp|Q96S90|LYSM1_HUMAN 1 1021.6284 4.4 2009 13760 2 1021.630628 511.8215 LysM and putative peptidoglycan-binding domain-containing protein 1 OS=Homo sapiens OX=9606 GN=LYSMD1 PE=1 SV=1 9.79 3005.5 - 208309 - - - 2.1661 - 1.52 0.09 - 118.9 2 2 0 0.0022 10 0 0 0 4.26E+06 9.68E+05 - - - 0.7393 0.9692 230117_WJC_METTL3_WT_vs_EV_F01.13775.13775.2 1.73 16-Aug K.SLTMVALAK.L "sp|P83111|LACTB_HUMAN,tr|H0YNN5|H0YNN5_HUMAN" 2 932.5365 1.33 2018 13775 2 932.539778 467.2755 "Serine beta-lactamase-like protein LACTB, mitochondrial OS=Homo sapiens OX=9606 GN=LACTB PE=1 SV=2" 8.47 3007.5 - 221100 - - - 3.5269 - 1.082 0.144 - 112.5 1 2 0 0.0033 9 0 0 0 7.02E+06 5.29E+06 - - - 0.3316 0.8655 230117_WJC_METTL3_WT_vs_EV_F01.13781.13781.2 2.26 14-Jul K.KPEEQHNK.S sp|Q9H8T0|AKTIP_HUMAN 1 1008.4989 1.78 2022 13781 2 1008.504139 505.2567 AKT-interacting protein OS=Homo sapiens OX=9606 GN=AKTIP PE=1 SV=1 6.76 3008.2 - 449588 - - - 5.2365 - 1.214 0.058 - 129 1 2 0 0.0053 8 0 0 0 2.04E+07 1.14E+07 - - - 0.0526 0.9907 230117_WJC_METTL3_WT_vs_EV_F01.13806.13806.2 0.378 14-Jul R.FLGC[160.03]VDIK.D "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 950.4895 1.52 2037 13806 2 950.491814 476.252 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 5.83 3011.2 - 1.38E+06 - - - 2.3935 - 1.018 0.219 - 129.1 1 2 0 0.0023 8 0 0 0 4.46E+07 2.93E+07 - - - 0.7116 0.9026 230117_WJC_METTL3_WT_vs_EV_F01.13810.13810.2 9.89 12-May K.FLSDIVR.V "sp|Q9NR09|BIRC6_HUMAN,tr|A0A3B3IUB9|A0A3B3IUB9_HUMAN" 2 848.4756 0.4 2041 13810 2 848.475464 425.2451 Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=BIRC6 PE=1 SV=2 5.84 3011.6 - 446877 - - - -0.1638 - 1.116 0.04 - 52.3 9 2 0 -0.0001 7 0 0 0 1.38E+07 3.42E+07 - - - -0.7421 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.13814.13814.2 0.0191 14-Jul K.AAFAPFGR.L "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 5 835.4341 1.85 2043 13814 2 835.435786 418.7243 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 9.79 3012.1 - 804820 - - - 2.0504 - 1.534 0.26 - 168.5 1 2 0 0.0017 8 0 0 0 2.29E+07 1.24E+07 - - - 2.2513 0.9837 230117_WJC_METTL3_WT_vs_EV_F01.13817.13817.2 3.32 14-Jun R.FLGC[160.03]VDIK[136.11].D "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 958.5037 1.86 2046 13817 2 958.504378 480.2591 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 5.83 3012.3 - 1.18E+06 - - - 0.6667 - 1.014 0.152 - 68.8 1 2 0 0.0006 8 0 0 0 4.34E+07 2.33E+07 - - - 0.2054 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.13818.13818.2 0.187 14-Jul K.VLVPQIPR[166.11].L sp|Q10469|MGAT2_HUMAN 1 930.589 1.1 2047 13818 2 930.590473 466.3018 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 3012.5 - 726416 - - - 1.5753 - 1.361 0.268 - 152.5 1 2 0 0.0015 8 0 0 0 1.21E+08 1.10E+08 - - - 1.9496 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.13820.13820.2 0.00044 22-Dec R.TVIIEQSWGSPK[136.11].V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1351.7227 2.7 2049 13820 2 1351.726018 676.8686 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 3012.7 - 182223 - - - 2.4428 - 2.411 0.431 - 460.2 1 2 0 0.0033 12 0 0 0 1.43E+07 5.28E+06 - - - 4.5389 1 230117_WJC_METTL3_WT_vs_EV_F01.13825.13825.2 0.00716 13/22 R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 2.7 2052 13825 2 1343.711834 672.8615 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 3013.4 - 335833 - - - 2.4693 - 2.498 0.452 - 579.1 1 2 0 0.0033 12 0 0 0 1.43E+07 5.28E+06 - - - 4.7872 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.13826.13826.2 0.00413 16-Sep K.VPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1071.5601 1.71 2053 13826 2 1071.561523 536.7873 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 3013.5 - 299520 - - - 1.3644 - 1.319 0.362 - 223.5 1 2 0 0.0015 9 0 0 0 2.05E+07 1.20E+07 - - - 2.5153 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.13831.13831.2 0.103 14-Jun K.VLVPQIPR.L sp|Q10469|MGAT2_HUMAN 1 920.5807 1.11 2056 13831 2 920.582373 461.2976 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 3014.1 - 847507 - - - 1.7771 - 1.103 0.369 - 137.1 1 2 0 0.0016 8 0 0 0 1.22E+08 1.10E+08 - - - 2.0616 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.13834.13834.2 0.167 12-May R.FC[160.03]EMLIK.R "sp|Q8WV92|MITD1_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 2 939.4558 0.61 2059 13834 2 939.457378 470.7352 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 5.99 3014.4 - 300921 - - - 1.684 - 1.09 0.253 - 62.1 1 2 0 0.0016 7 0 0 0 2.20E+07 3.58E+07 - - - 1.1822 0.9886 230117_WJC_METTL3_WT_vs_EV_F01.13837.13837.2 1.2 12-Aug K.FTAILYR.T "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 882.4963 0.75 2060 13837 2 882.500225 442.2554 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.75 3014.8 - 1.02E+06 - - - 4.4034 - 1.615 0.132 - 271.7 1 2 0 0.0039 7 0 0 0 1.94E+08 2.58E+08 - - - 1.5335 0.9059 230117_WJC_METTL3_WT_vs_EV_F01.13847.13847.2 0.0142 18-Jun K.LYTGPGLAIH.C "sp|O43670|ZN207_HUMAN,tr|J3QRS9|J3QRS9_HUMAN,tr|X6R4W8|X6R4W8_HUMAN" 3 1040.5655 - 2066 13847 2 1040.566255 521.29 BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1 6.74 3016 - 317635 - - - 0.7438 - 1.316 0.323 - 61.7 1 1 0 0.0008 10 0 0 0 - - - - - 2.1929 0.992 230117_WJC_METTL3_WT_vs_EV_F01.13853.13853.2 0.0102 16-Aug K.YDGIILPGK[136.11].- "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 982.5579 1.22 2069 13853 2 982.55607 492.2862 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.83 3016.7 - 341512 - - - -1.8452 - 1.255 0.291 - 205.1 1 2 0 -0.0018 9 0 0 0 4.12E+07 3.37E+07 - - - 1.8469 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.13857.13857.2 0.816 12-Jul K.LVYILNR[166.11].D sp|Q15393|SF3B3_HUMAN 1 899.5468 1.28 2073 13857 2 899.547692 450.7807 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 3016.9 - 2.14E+06 - - - 0.9827 - 1.432 0.159 - 143.5 1 2 0 0.0009 7 0 0 0 4.42E+08 3.45E+08 - - - 1.3528 0.9933 230117_WJC_METTL3_WT_vs_EV_F01.13863.13863.2 1.65 12-Jul R.ISPLQFR.- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 859.4916 3.06 2077 13863 2 859.492971 430.7531 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 3017.7 - 4.05E+06 - - - 1.6091 - 1.438 0.078 - 207.8 1 2 0 0.0014 7 0 0 0 5.17E+08 1.69E+08 - - - 0.7677 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.13871.13871.2 0.166 12-Jul K.LVYILNR.D sp|Q15393|SF3B3_HUMAN 1 889.5385 1.28 2083 13871 2 889.540392 445.7765 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 3018.6 - 5.25E+06 - - - 2.0842 - 1.334 0.229 - 189.7 1 2 0 0.0019 7 0 0 0 4.42E+08 3.45E+08 - - - 1.6449 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.13873.13873.2 0.00931 14-Aug K.ITAFIVER.D "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 947.544 0.64 2085 13873 2 947.547418 474.7793 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 6 3018.8 - 610818 - - - 3.5893 - 1.724 0.291 - 136.3 1 2 0 0.0034 8 0 0 0 7.97E+07 1.24E+08 - - - 2.8319 0.997 230117_WJC_METTL3_WT_vs_EV_F01.13874.13874.2 0.0989 14-Jul R.VIFTSPIK[136.11].A sp|P42285|MTREX_HUMAN 1 911.5572 1.14 2086 13874 2 911.559637 456.7859 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 8.72 3018.9 - 427005 - - - 2.7239 - 1.284 0.264 - 137.7 1 2 0 0.0025 8 0 0 0 1.46E+08 1.29E+08 - - - 1.7441 0.995 230117_WJC_METTL3_WT_vs_EV_F01.13879.13879.2 0.353 12-Aug K.NLIEVMR.K sp|Q9Y512|SAM50_HUMAN 1 873.4742 2.99 2089 13879 2 873.475913 437.7444 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 6 3019.5 - 538600 - - - 1.9348 - 1.39 0.129 - 223.1 1 2 0 0.0017 7 0 0 0 3.98E+07 1.33E+07 - - - 1.0367 0.9875 230117_WJC_METTL3_WT_vs_EV_F01.13880.13880.2 0.221 12-Jul R.ISPLQFR[166.11].- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 869.4999 3.06 2090 13880 2 869.501455 435.7572 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 3019.6 - 2.07E+06 - - - 1.8367 - 1.278 0.073 - 188.2 1 2 0 0.0016 7 0 0 0 5.17E+08 1.69E+08 - - - 0.3569 0.9959 230117_WJC_METTL3_WT_vs_EV_F01.13889.13889.2 32.1 12-Jul R.LVQLLVK.A sp|P14923|PLAK_HUMAN 1 811.5531 16.54 2094 13889 2 811.554164 406.7838 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 8.75 3020.7 - 1.23E+06 - - - 1.2803 - 1.714 0.07 - 117.1 2 2 0 0.001 7 0 0 0 3.17E+08 1.91E+07 - - - 1.1305 0.968 230117_WJC_METTL3_WT_vs_EV_F01.13901.13901.2 1.38 20-Jun R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 62.53 2099 13901 2 1068.658949 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 3022.3 - 664023 - - - 4.3541 - 1.4 0.13 - 67.5 3 2 0 0.0047 11 0 0 0 1.07E+08 1.71E+06 - - - 0.6968 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.13903.13903.2 0.0139 14-Aug K.ITAFIVER[166.11].D "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 957.5523 1.01 2100 13903 2 957.553689 479.7834 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 6 3022.5 - 2.34E+06 - - - 1.4641 - 1.725 0.32 - 196.6 1 2 0 0.0014 8 0 0 0 1.32E+08 1.30E+08 - - - 3.0485 0.9879 230117_WJC_METTL3_WT_vs_EV_F01.13923.13923.2 0.47 16-Jun R.IIFSPVAPK[136.11].E sp|O15294|OGT1_HUMAN 1 978.5994 1.36 2109 13923 2 978.600868 490.307 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 8.75 3025.1 - 533243 - - - 1.5471 - 1.123 0.16 - 58.2 3 2 0 0.0015 9 0 0 0 1.06E+08 7.80E+07 - - - 0.3448 0.9909 230117_WJC_METTL3_WT_vs_EV_F01.13932.13932.2 0.0119 14-Sep R.LATEFELR.K sp|A5YKK6|CNOT1_HUMAN 1 977.5182 0.82 2112 13932 2 977.51541 489.7664 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.53 3026.5 - 538031 - - - -2.8501 - 1.574 0.261 - 197.7 1 2 0 -0.0028 8 0 0 0 2.08E+07 2.54E+07 - - - 2.336 0.9894 230117_WJC_METTL3_WT_vs_EV_F01.13938.13938.2 0.326 12-Jun R.TIPVVFK.D "sp|P25685|DNJB1_HUMAN,tr|A0A7I2V3K7|A0A7I2V3K7_HUMAN" 2 802.4953 0.66 2116 13938 2 802.498746 402.2549 DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4 8.41 3027.1 - 1.04E+06 - - - 4.324 - 1.263 0.24 - 118.5 1 2 0 0.0035 7 0 0 0 6.14E+07 9.34E+07 - - - 1.5524 0.9848 230117_WJC_METTL3_WT_vs_EV_F01.13951.13951.2 1.25 14-Sep R.LATEFELR[166.11].K sp|A5YKK6|CNOT1_HUMAN 1 987.5265 0.84 2120 13951 2 987.529639 494.7705 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.53 3028.9 - 426732 - - - 3.2131 - 1.443 0.074 - 256.2 1 2 0 0.0032 8 0 0 0 2.18E+07 2.60E+07 - - - 0.6926 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.13953.13953.2 0.0259 16-Sep R.VPPEFLVQR.A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1083.6077 1.39 2122 13953 2 1083.608204 542.8111 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3029.2 - 671212 - - - 0.4836 - 1.474 0.248 - 253.4 1 2 0 0.0005 9 0 0 0 1.06E+08 7.68E+07 - - - 1.995 0.9681 230117_WJC_METTL3_WT_vs_EV_F01.13954.13954.2 0.0726 16-Aug K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 4.68 2123 13954 2 1014.541384 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3029.3 - 308431 - - - 6.7115 - 1.553 0.226 - 132.3 1 2 0 0.0068 9 0 0 0 9.50E+06 2.03E+06 - - - 1.9816 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.13956.13956.2 0.000105 18-Dec R.MVNHFIAEFK.R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1234.6169 3.64 2124 13956 2 1234.619394 618.3157 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 3029.5 - 247594 - - - 2.0484 - 1.934 0.2 - 492.8 1 2 0 0.0025 10 0 0 0 9.05E+06 2.48E+06 - - - 2.3585 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.13958.13958.3 0.0185 Aug-36 R.MVNHFIAEFK.R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1234.6169 3.6 2125 13958 3 1234.618024 412.5462 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 3029.7 - 1.66E+06 - - - 0.9388 - 1.399 0.307 - 57.5 1 2 0 0.0012 10 0 0 0 4.90E+07 1.36E+07 - - - 2.943 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.13959.13959.2 0.0802 12-Jul R.YYFEGIK.Q "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN" 3 918.4487 2.28 2126 13959 2 918.449852 460.2316 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 6 3029.8 - 1.25E+06 - - - 1.2325 - 1.145 0.281 - 135 1 2 0 0.0011 7 0 0 0 5.91E+07 2.59E+07 - - - 1.5451 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.13965.13965.2 0.0126 16-Aug R.VPPEFLVQR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1093.616 1.58 2129 13965 2 1093.615655 547.8153 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3030.5 - 424150 - - - -0.2697 - 1.504 0.267 - 243.5 1 2 0 -0.0003 9 0 0 0 5.35E+07 3.39E+07 - - - 2.1937 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.13966.13966.2 2.4 18-Jun R.VLAESLGPLR.E sp|Q4KMQ1|TPRN_HUMAN 1 1053.6182 0.98 2130 13966 2 1053.618578 527.8164 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 5.97 3030.7 - 405342 - - - 0.3161 - 1.425 0.223 - 69.2 3 2 0 0.0003 10 0 0 0 6.80E+07 6.95E+07 - - - 1.4634 0.9853 230117_WJC_METTL3_WT_vs_EV_F01.13971.13971.2 0.122 14-Jun R.LPWAVAGR.S sp|Q8NBX0|SCPDL_HUMAN 1 868.4919 2.04 2133 13971 2 868.492302 435.2532 Saccharopine dehydrogenase-like oxidoreductase OS=Homo sapiens OX=9606 GN=SCCPDH PE=1 SV=1 9.75 3031.3 - 833136 - - - 0.4375 - 1.174 0.109 - 88.5 1 2 0 0.0004 8 0 0 0 7.23E+07 3.54E+07 - - - 0.3298 0.9894 230117_WJC_METTL3_WT_vs_EV_F01.13982.13982.2 0.0559 20-Jul R.LLADPTGAFGK.E sp|P30044|PRDX5_HUMAN 1 1088.5866 3.11 2138 13982 2 1088.592905 545.3006 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.84 3032.7 - 172592 - - - 5.7827 - 1.561 0.324 - 77.9 2 2 0 0.0063 11 0 0 0 2.99E+07 9.64E+06 - - - 2.5023 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.13984.13984.2 0.00108 12-Jul K.LFEMAYK.K "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 900.4415 4.35 2139 13984 2 900.442949 451.228 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6 3032.9 - 2.92E+06 - - - 1.5803 - 1.463 0.405 - 164.4 1 2 0 0.0014 7 0 0 0 1.33E+09 3.05E+08 - - - 3.2375 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.13990.13990.2 0.0243 12-Jul K.LFEMAYK[136.11].K "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 908.4557 4.35 2143 13990 2 908.457219 455.2351 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6 3033.6 - 1.25E+06 - - - 1.6434 - 1.456 0.322 - 141.4 1 2 0 0.0015 7 0 0 0 1.33E+09 3.05E+08 - - - 2.6092 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.13992.13992.2 0.00824 18-Sep K.VLQSALAAIR.H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1040.6342 1.08 2145 13992 2 1040.634793 521.3244 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 3033.9 - 273750 - - - 0.542 - 1.71 0.381 - 217.8 1 2 0 0.0006 10 0 0 0 3.50E+08 3.25E+08 - - - 3.3524 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.13995.13995.2 0.000162 16-Sep R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 999 2146 13995 2 1030.592199 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 3034.3 - 5.44E+07 - - - 1.1372 - 1.973 0.428 - 240.8 1 2 0 0.0012 9 0 0 0 5.77E+09 0.00E+00 - - - 4.1678 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.14002.14002.2 0.00634 20-Jul K.VMPTLAPVVAK.L sp|Q8IWI9|MGAP_HUMAN 1 1124.6628 1.33 2149 14002 2 1124.660925 563.3387 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 8.72 3035.1 - 102670 - - - -1.6245 - 1.475 0.377 - 95 1 2 0 -0.0018 11 0 0 0 6.80E+06 5.10E+06 - - - 2.8764 0.9942 230117_WJC_METTL3_WT_vs_EV_F01.14005.14005.2 0.559 12-Aug K.IPWSALK[136.11].T "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 8 821.4891 2.73 2151 14005 2 821.490276 411.7518 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.75 3035.5 - 292698 - - - 1.462 - 1.468 0.083 - 144.9 1 2 0 0.0012 7 0 0 0 6.95E+07 2.54E+07 - - - 0.8701 0.9901 230117_WJC_METTL3_WT_vs_EV_F01.14007.14007.2 0.912 12-Jul R.LELDALR.S "sp|O60675|MAFK_HUMAN,sp|Q9ULX9|MAFF_HUMAN,sp|O15525|MAFG_HUMAN,tr|B0QY71|B0QY71_HUMAN,tr|B0QY70|B0QY70_HUMAN" 5 828.4705 0.61 2153 14007 2 828.471045 415.2425 Transcription factor MafK OS=Homo sapiens OX=9606 GN=MAFK PE=1 SV=1 4.37 3035.7 - 261349 - - - 0.6361 - 1.351 0.076 - 133.9 1 2 0 0.0005 7 0 0 0 1.97E+07 3.22E+07 - - - 0.5554 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.14010.14010.2 0.00304 14-Jul R.VLVLVPTR.E "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 895.5855 0.89 2154 14010 2 895.585988 448.8 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 9.72 3036.1 - 1.56E+06 - - - 0.5583 - 1.628 0.151 - 164.4 1 2 0 0.0005 8 0 0 0 7.41E+07 8.32E+07 - - - 1.626 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.14012.14012.2 0.0233 18-Oct K.VLQSALAAIR[166.11].H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1050.6425 1.08 2156 14012 2 1050.6428 526.3285 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 3036.3 - 2.16E+06 - - - 0.2865 - 2.122 0.426 - 314.1 1 2 0 0.0003 10 0 0 0 3.50E+08 3.25E+08 - - - 4.2874 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.14020.14020.2 0.00156 18-Dec R.VLAESLGPLR[166.11].E sp|Q4KMQ1|TPRN_HUMAN 1 1063.6265 0.96 2160 14020 2 1063.626187 532.8205 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 5.97 3037.3 - 1.09E+06 - - - -0.3084 - 1.995 0.353 - 501.2 1 2 0 -0.0003 10 0 0 0 6.89E+07 7.19E+07 - - - 3.576 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.14021.14021.2 0.102 18-Dec K.LAEALYIADR.K "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1133.6081 0.58 2161 14021 2 1133.608779 567.8113 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 3037.4 - 450232 - - - 0.6219 - 2.547 0.328 - 604.7 1 2 0 0.0007 10 0 0 0 7.28E+07 1.26E+08 - - - 4.073 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.14025.14025.2 0.00351 14/18 K.LAEALYIADR[166.11].K "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1143.6163 0.48 2163 14025 2 1143.618527 572.8154 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 3038 - 521931 - - - 1.9089 - 2.507 0.318 - 799.7 1 2 0 0.0022 10 0 0 0 7.30E+07 1.51E+08 - - - 3.9545 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.14035.14035.2 0.111 14-Jul R.YPEEFALR.D "sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN" 4 1023.5025 0.34 2167 14035 2 1023.505067 512.7585 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.53 3039.2 - 345485 - - - 2.4631 - 1.142 0.325 - 145.4 1 2 0 0.0025 8 0 0 0 1.61E+07 4.76E+07 - - - 1.8411 0.8912 230117_WJC_METTL3_WT_vs_EV_F01.14042.14042.4 0.0934 Oct-96 T.LLLIILTDVFIISTVLR.L sp|Q8NGY0|O10X1_HUMAN 1 1941.2278 4114.34 2173 14042 4 1941.233791 486.3142 Olfactory receptor 10X1 OS=Homo sapiens OX=9606 GN=OR10X1 PE=3 SV=2 5.84 3039.8 - 395662 - - - 3.0749 - 1.663 0.243 - 40.3 1 1 0 0.006 17 0 0 0 1.39E+08 3.38E+04 - - - 1.516 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.14045.14045.2 0.0298 14-Jul R.LPLATIVK[136.11].D sp|O94776|MTA2_HUMAN 1 861.5779 1.53 2174 14045 2 861.578779 431.7962 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 3040.2 - 907783 - - - 1.0318 - 1.206 0.364 - 75.2 1 2 0 0.0009 8 0 0 0 3.36E+08 2.20E+08 - - - 2.2941 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.14046.14046.2 0.000385 16-Aug K.FTPGAVMLR.V "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 990.5321 1.2 2175 14046 2 990.531429 496.2733 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.75 3040.3 - 733951 - - - -0.6491 - 1.496 0.452 - 197.7 1 2 0 -0.0006 9 0 0 0 5.52E+07 4.60E+07 - - - 3.5446 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.14052.14052.2 0.39 12-Jun R.LVWYC[160.03]AR[166.11].C "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 976.4828 1.84 2179 14052 2 976.483242 489.2487 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.22 3041 - 205320 - - - 0.424 - 1.156 0.283 - 105.4 1 2 0 0.0004 7 0 0 0 2.21E+07 1.20E+07 - - - 1.5904 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.14053.14053.2 0.071 12-Jun R.LVWYC[160.03]AR.C "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 966.4746 1.81 2180 14053 2 966.476171 484.2446 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.22 3041.2 - 323996 - - - 1.669 - 1.161 0.368 - 108.2 1 2 0 0.0016 7 0 0 0 2.26E+07 1.25E+07 - - - 2.2315 0.9614 230117_WJC_METTL3_WT_vs_EV_F01.14054.14054.2 2.31 12-May R.FPPYYMR[166.11].R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 982.461 0.99 2181 14054 2 982.462218 492.2378 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 3041.3 - 184865 - - - 1.2102 - 0.876 0.129 - 68 1 2 0 0.0012 7 0 0 0 1.74E+07 1.77E+07 - - - -0.4261 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.14056.14056.2 0.0357 12-Jun K.FYIDPYK[136.11].L sp|Q9NY12|GAR1_HUMAN 1 952.4786 0.8 2182 14056 2 952.479205 477.2466 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3041.5 - 5.21E+06 - - - 0.6667 - 1.416 0.305 - 146.5 1 2 0 0.0006 7 0 0 0 1.38E+09 1.72E+09 - - - 2.3957 0.9708 230117_WJC_METTL3_WT_vs_EV_F01.14059.14059.2 0.775 16-May R.VVSEIPVLK.T sp|Q9Y3C8|UFC1_HUMAN 1 982.6063 1.62 2184 14059 2 982.60701 492.3104 Ubiquitin-fold modifier-conjugating enzyme 1 OS=Homo sapiens OX=9606 GN=UFC1 PE=1 SV=3 5.97 3041.9 - 336107 - - - 0.7399 - 0.972 0.151 - 46.2 4 2 0 0.0007 9 0 0 0 1.15E+07 7.08E+06 - - - -0.195 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.14064.14064.2 0.00745 14-Aug R.LPLATIVK.D sp|O94776|MTA2_HUMAN 1 853.5637 1.53 2187 14064 2 853.565087 427.7891 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 3042.5 - 1.95E+06 - - - 1.6367 - 1.664 0.373 - 185.7 1 2 0 0.0014 8 0 0 0 3.36E+08 2.20E+08 - - - 3.3313 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.14075.14075.2 0.00919 14-Aug K.IDNIVLMK[136.11].D "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 952.5507 2.63 2192 14075 2 952.550969 477.2826 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 5.84 3043.9 - 2.73E+06 - - - 0.2939 - 1.589 0.277 - 148.2 1 2 0 0.0003 8 0 0 0 1.25E+08 4.74E+07 - - - 2.4835 1 230117_WJC_METTL3_WT_vs_EV_F01.14088.14088.2 4.76E-06 18-Nov R.VPLVAPEDLR[166.11].D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1117.6371 0.5 2198 14088 2 1117.639437 559.8258 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3045.5 - 516093 - - - 2.1098 - 2.431 0.521 - 493.9 1 2 0 0.0024 10 0 0 0 1.05E+09 2.08E+09 - - - 5.3679 0.9895 230117_WJC_METTL3_WT_vs_EV_F01.14092.14092.2 0.278 16-Jul K.FTPGAVMLR[166.11].V "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1000.5403 1.98 2200 14092 2 1000.540621 501.2774 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.75 3046 - 757030 - - - 0.2788 - 1.32 0.104 - 134.9 1 2 0 0.0003 9 0 0 0 4.92E+07 2.49E+07 - - - 0.6123 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.14103.14103.2 0.0822 18-Nov R.VPLVAPEDLR.D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1107.6288 0.5 2207 14103 2 1107.628936 554.8217 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3047.1 - 619892 - - - 0.1147 - 2.279 0.39 - 546.4 1 2 0 0.0001 10 0 0 0 1.05E+09 2.08E+09 - - - 4.2208 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.14107.14107.2 0.149 14-Jul K.LYLADPMK.A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 949.4943 1.64 2209 14107 2 949.493646 475.7544 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 3047.5 - 2.13E+06 - - - -0.6783 - 1.343 0.268 - 142.7 1 2 0 -0.0006 8 0 0 0 3.68E+08 2.25E+08 - - - 1.9097 0.9962 230117_WJC_METTL3_WT_vs_EV_F01.14108.14108.2 2.55 14-Jun R.AQVSLLIR[166.11].R "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 908.5683 1.27 2210 14108 2 908.568576 455.2914 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 9.79 3047.6 - 495047 - - - 0.3346 - 1.341 0.196 - 96.6 1 2 0 0.0003 8 0 0 0 6.25E+07 4.91E+07 - - - 1.3735 0.9928 230117_WJC_METTL3_WT_vs_EV_F01.14125.14125.2 0.0493 14-Jul K.LYLADPMK[136.11].A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 957.5085 1.64 2219 14125 2 957.507025 479.7615 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 3049.6 - 2.30E+06 - - - -1.53 - 1.278 0.268 - 150.6 1 2 0 -0.0015 8 0 0 0 3.69E+08 2.26E+08 - - - 1.7598 0.9342 230117_WJC_METTL3_WT_vs_EV_F01.14142.14142.2 0.0412 18-May K.NLQEAEEWYK[136.11].S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1316.6128 1.82 2229 14142 2 1316.607556 659.3137 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3051.9 - 223291 - - - -4.0073 - 1.108 0.268 - 53.2 2 2 0 -0.0053 10 0 0 0 2.01E+07 1.10E+07 - - - 1.1706 0.9716 230117_WJC_METTL3_WT_vs_EV_F01.14147.14147.2 3.12 20-Jun R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 999 2231 14147 2 1068.659314 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 3052.5 - 3.24E+06 - - - 4.6956 - 1.341 0.152 - 81 1 2 0 0.005 11 0 0 0 2.16E+08 0.00E+00 - - - 0.9559 0.9923 230117_WJC_METTL3_WT_vs_EV_F01.14149.14149.2 0.296 12-May R.LYFC[160.03]VDR.G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 971.4535 1.85 2233 14149 2 971.452341 486.734 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 5.83 3052.6 - 1.75E+06 - - - -1.1807 - 1.282 0.228 - 60 1 2 0 -0.0011 7 0 0 0 9.81E+07 5.31E+07 - - - 1.5118 0.9457 230117_WJC_METTL3_WT_vs_EV_F01.14155.14155.2 5.8 12-Jun R.IYPELLK[136.11].R "sp|Q86Y56|DAAF5_HUMAN,tr|H0Y650|H0Y650_HUMAN,tr|E9PGY2|E9PGY2_HUMAN" 3 882.5306 1.63 2237 14155 2 882.531529 442.2726 Dynein axonemal assembly factor 5 OS=Homo sapiens OX=9606 GN=DNAAF5 PE=1 SV=4 6 3053.2 - 654555 - - - 1.047 - 0.891 0.093 - 64.5 1 2 0 0.0009 7 0 0 0 4.99E+07 3.06E+07 - - - -0.6381 1 230117_WJC_METTL3_WT_vs_EV_F01.14156.14156.2 1.39E-05 18-Oct K.NLQEAEEWYK.S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1308.5986 1.82 2238 14156 2 1308.598335 655.3066 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3053.4 - 591311 - - - -0.227 - 1.969 0.55 - 352.8 1 2 0 -0.0003 10 0 0 0 2.01E+07 1.10E+07 - - - 4.9944 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.14164.14164.2 0.000326 26-Sep K.IFVGGLSPDTPEEK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1487.7508 1.43 2240 14164 2 1487.750507 744.8827 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3054.5 - 215081 - - - -0.1801 - 1.832 0.467 - 122.5 1 2 0 -0.0003 14 0 0 0 1.12E+07 7.85E+06 - - - 4.0094 0.9918 230117_WJC_METTL3_WT_vs_EV_F01.14174.14174.2 5.47 14-Jul K.LLGPVLVK.Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 837.5688 3.8 2243 14174 2 837.569751 419.7917 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 3056 - 2.54E+06 - - - 1.1653 - 1.359 0.088 - 98 1 2 0 0.001 8 0 0 0 1.21E+09 3.18E+08 - - - 0.6158 0.9779 230117_WJC_METTL3_WT_vs_EV_F01.14175.14175.2 2.67 12-Jul K.VTLGLIR[166.11].K sp|Q9NQT5|EXOS3_HUMAN 1 780.5097 1.11 2244 14175 2 780.510546 391.2621 Exosome complex component RRP40 OS=Homo sapiens OX=9606 GN=EXOSC3 PE=1 SV=3 9.72 3056.1 - 3.83E+06 - - - 1.0916 - 1.145 0.064 - 224.2 1 2 0 0.0009 7 0 0 0 7.78E+07 7.03E+07 - - - -0.0575 1 230117_WJC_METTL3_WT_vs_EV_F01.14176.14176.2 9.70E-05 20-Dec K.YFVEAGAMAVR.R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1212.5961 9.85 2245 14176 2 1212.594834 607.3053 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3056.2 - 801977 - - - -1.068 - 2.362 0.58 - 558.5 1 2 0 -0.0013 11 0 0 0 9.88E+08 1.00E+08 - - - 5.6496 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.14183.14183.2 3.49E-05 26-Aug K.IFVGGLSPDTPEEK[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1495.765 1.43 2249 14183 2 1495.765533 748.8898 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3057 - 109778 - - - 0.3731 - 1.582 0.533 - 80.6 1 2 0 0.0006 14 0 0 0 1.12E+07 7.85E+06 - - - 4.1286 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.14190.14190.2 0.467 16-Oct K.LADMGIAIR[166.11].V sp|Q9Y3I0|RTCB_HUMAN 1 968.5353 1.24 2254 14190 2 968.536382 485.2749 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.84 3057.7 - 3.02E+06 - - - 1.1615 - 1.837 0.185 - 359.7 1 2 0 0.0011 9 0 0 0 3.45E+08 2.79E+08 - - - 2.1664 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.14191.14191.2 2.55 14-Jun K.LLGPVLVK[136.11].Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 845.583 3.8 2255 14191 2 845.583293 423.7988 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 3057.8 - 2.40E+06 - - - 0.3761 - 1.304 0.185 - 69.3 1 2 0 0.0003 8 0 0 0 1.21E+09 3.18E+08 - - - 1.2079 0.9481 230117_WJC_METTL3_WT_vs_EV_F01.14199.14199.2 22.4 12-Jun R.LISSLLR[166.11].T "sp|Q9BQ52|RNZ2_HUMAN,sp|Q8NCN5|PDPR_HUMAN,sp|Q96P20|NLRP3_HUMAN,sp|Q96MN2|NALP4_HUMAN,sp|Q8NGV5|O13D1_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|A0A7I2PMC6|A0A7I2PMC6_HUMAN,tr|E7ES68|E7ES68_HUMAN,tr|A0A2R8YEG7|A0A2R8YEG7_HUMAN,tr|A8MT40|A8MT40_HUMAN,tr|A0A7I2PJH0|A0A7I2PJH0_HUMAN,tr|H3BQG3|H3BQG3_HUMAN,tr|A0A7I2PRX0|A0A7I2PRX0_HUMAN,tr|A0A7I2YME5|A0A7I2YME5_HUMAN,tr|A0A286YF94|A0A286YF94_HUMAN,tr|A0A7I2UNQ2|A0A7I2UNQ2_HUMAN,tr|A0A7I2R3P8|A0A7I2R3P8_HUMAN" 17 810.5203 1.74 2258 14199 2 810.521126 406.2674 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 9.75 3058.8 - 947762 - - - 1.0697 - 1.058 0.074 - 63.9 7 2 0 0.0009 7 0 0 0 7.51E+07 4.32E+07 - - - -0.6116 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.14209.14209.2 0.000221 16-Oct R.SPIAEAVFR.K "sp|P24666|PPAC_HUMAN,tr|D3YTI2|D3YTI2_HUMAN,tr|F2Z2Q9|F2Z2Q9_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 4 988.5342 0.1 2263 14209 2 988.537398 495.2744 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 5.72 3059.9 - 1.62E+06 - - - 3.2543 - 1.967 0.376 - 287.4 1 2 0 0.0032 9 0 0 0 1.08E+08 1.03E+09 - - - 3.7743 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.14218.14218.2 0.00307 20-Nov K.YFVEAGAMAVR[166.11].R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1222.6044 9.84 2269 14218 2 1222.604713 612.3095 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3061.1 - 1.83E+06 - - - 0.2568 - 1.507 0.434 - 257.2 1 2 0 0.0003 11 0 0 0 9.88E+08 1.00E+08 - - - 3.3559 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.14224.14224.2 0.0531 18-Sep R.VPYVIISAAK.G "sp|P28340|DPOD1_HUMAN,tr|M0QXQ2|M0QXQ2_HUMAN,tr|M0QXE6|M0QXE6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 5 1059.6328 0.11 2273 14224 2 1059.634504 530.8237 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.56 3061.7 - 285353 - - - 1.5779 - 1.676 0.231 - 158.5 1 2 0 0.0017 10 0 0 0 1.28E+07 1.13E+08 - - - 2.1881 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.14226.14226.2 0.01 22-Nov K.SPILVATAVAAR.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1167.6976 1.11 2275 14226 2 1167.697906 584.8561 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3061.9 - 231192 - - - 0.298 - 2.193 0.407 - 352.9 1 2 0 0.0003 12 0 0 0 5.75E+08 5.18E+08 - - - 4.1132 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.14228.14228.2 0.0276 12-Aug R.FTDILVR[166.11].H sp|O43143|DHX15_HUMAN 1 872.4995 1.12 2276 14228 2 872.500121 437.257 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 3062.1 - 6.42E+06 - - - 0.6854 - 1.581 0.353 - 241.9 1 2 0 0.0006 7 0 0 0 6.43E+08 5.75E+08 - - - 3.0995 0.9417 230117_WJC_METTL3_WT_vs_EV_F01.14230.14230.2 0.373 16-May R.VPPEFLVQR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1093.616 1.49 2277 14230 2 1093.621788 547.8153 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3062.3 - 372851 - - - 5.3383 - 1.113 0.187 - 72.6 1 2 0 0.0058 9 0 0 0 6.76E+07 4.55E+07 - - - 0.7301 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.14232.14232.2 0.00356 22-Dec K.SPILVATAVAAR[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1177.7058 1.11 2279 14232 2 1177.706466 589.8602 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3062.6 - 698036 - - - 0.5417 - 2.274 0.425 - 204.2 1 2 0 0.0006 12 0 0 0 5.75E+08 5.18E+08 - - - 4.3415 0.9882 230117_WJC_METTL3_WT_vs_EV_F01.14243.14243.2 0.75 12-Jun R.SLILAMK[136.11].A sp|Q7Z353|HDX_HUMAN 1 782.4815 0.53 2285 14243 2 782.483359 392.248 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 8.47 3064 - 2.32E+06 - - - 2.3157 - 1.205 0.12 - 162.4 1 2 0 0.0018 7 0 0 0 2.11E+07 3.97E+07 - - - 0.5176 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.14247.14247.2 0.00556 12-Aug R.FTDILVR.H sp|O43143|DHX15_HUMAN 1 862.4913 1.12 2287 14247 2 862.492226 432.2529 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 3064.5 - 5.72E+06 - - - 1.1281 - 1.531 0.302 - 237.5 1 2 0 0.001 7 0 0 0 6.43E+08 5.75E+08 - - - 2.6208 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.14249.14249.2 0.0381 14-Aug K.AINTFFAK[136.11].N "sp|Q71RC2|LARP4_HUMAN,tr|Q96J85|Q96J85_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 3 918.5055 1.71 2289 14249 2 918.508229 460.26 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 8.8 3064.7 - 1.34E+06 - - - 3.0223 - 1.415 0.364 - 169.8 1 2 0 0.0028 8 0 0 0 5.96E+07 3.49E+07 - - - 2.7756 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.14255.14255.2 0.0871 12-Aug K.IAWALSR.K sp|Q04760|LGUL_HUMAN 1 815.4654 1.08 2292 14255 2 815.465757 408.74 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 9.75 3065.5 - 2.82E+06 - - - 0.4709 - 1.614 0.089 - 209.2 1 2 0 0.0004 7 0 0 0 1.27E+08 1.17E+08 - - - 1.2151 0.9944 230117_WJC_METTL3_WT_vs_EV_F01.14256.14256.2 3.35 14-Aug K.GIGLAIVR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 807.5206 0.89 2293 14256 2 807.520699 404.7676 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 3065.6 - 1.82E+06 - - - 0.1313 - 1.403 0.144 - 207.7 1 2 0 0.0001 8 0 0 0 4.23E+08 4.75E+08 - - - 1.1258 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.14259.14259.2 0.0436 12-Aug R.VFDMLNR.R "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 12 893.4429 1.54 2294 14259 2 893.44383 447.7287 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3066 - 1.57E+06 - - - 1.0152 - 1.353 0.256 - 283.2 1 2 0 0.0009 7 0 0 0 7.90E+07 5.13E+07 - - - 1.8895 0.9751 230117_WJC_METTL3_WT_vs_EV_F01.14271.14271.2 0.922 12-Jun R.LILPYER.F "sp|Q14865|ARI5B_HUMAN,tr|A0A7P0TAD2|A0A7P0TAD2_HUMAN" 2 902.5226 1.49 2300 14271 2 902.52311 452.2686 AT-rich interactive domain-containing protein 5B OS=Homo sapiens OX=9606 GN=ARID5B PE=1 SV=3 6 3067.6 - 585761 - - - 0.6172 - 1.123 0.071 - 123.4 1 2 0 0.0006 7 0 0 0 2.09E+07 1.40E+07 - - - -0.0672 0.9761 230117_WJC_METTL3_WT_vs_EV_F01.14274.14274.2 0.157 16-Jul K.VLPLEEAYR.F sp|Q9H223|EHD4_HUMAN 1 1088.5866 2.32 2302 14274 2 1088.592529 545.3006 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 3067.9 - 382898 - - - 5.4373 - 1.348 0.216 - 157.6 1 2 0 0.0059 9 0 0 0 1.97E+08 8.50E+07 - - - 1.4984 0.9631 230117_WJC_METTL3_WT_vs_EV_F01.14279.14279.2 9.12 12-Jul R.QSILILK.E "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 3 813.5324 2.66 2305 14279 2 813.533808 407.7735 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 8.75 3068.5 - 3.57E+06 - - - 1.743 - 1.164 0.014 - 148.1 1 2 0 0.0014 7 0 0 0 1.04E+08 3.93E+07 - - - -0.3749 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.14289.14289.2 0.0456 14-Jul R.LLAMLEQK.N "sp|Q96EA4|SPDLY_HUMAN,tr|H0YBG5|H0YBG5_HUMAN" 2 944.5365 9.79 2311 14289 2 944.537174 473.2755 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 6 3069.7 - 1.39E+06 - - - 0.7252 - 1.522 0.353 - 101.1 1 2 0 0.0007 8 0 0 0 3.75E+07 3.84E+06 - - - 2.9148 0.8478 230117_WJC_METTL3_WT_vs_EV_F01.14296.14296.2 1.39 12-Jul D.LIISELR[166.11].E "sp|O14732|IMPA2_HUMAN,sp|P61289|PSME3_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|Q6PIP6|Q6PIP6_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN,tr|K7EL65|K7EL65_HUMAN,tr|K7ELF8|K7ELF8_HUMAN" 9 852.5308 1.81 2316 14296 2 852.531873 427.2727 Inositol monophosphatase 2 OS=Homo sapiens OX=9606 GN=IMPA2 PE=1 SV=1 6 3070.3 - 2.19E+06 - - - 1.2316 - 1.585 0.151 - 183.7 1 1 0 0.001 7 0 0 0 2.56E+08 1.42E+08 - - - 1.6153 0.994 230117_WJC_METTL3_WT_vs_EV_F01.14303.14303.2 0.595 14-Aug R.MLQAMGWK[136.11].E sp|P98175|RBM10_HUMAN 1 971.4812 0.62 2319 14303 2 971.482465 486.7479 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 8.5 3071.2 - 591947 - - - 1.2723 - 1.14 0.189 - 118.4 1 2 0 0.0012 8 0 0 0 8.55E+06 1.37E+07 - - - 0.8317 0.9956 230117_WJC_METTL3_WT_vs_EV_F01.14308.14308.2 0.644 14-Jul R.LLLIATGK.R "sp|Q9NQW6|ANLN_HUMAN,tr|H7C1K5|H7C1K5_HUMAN" 2 827.548 0.05 2322 14308 2 827.548485 414.7813 Anillin OS=Homo sapiens OX=9606 GN=ANLN PE=1 SV=2 8.75 3071.9 - 1.19E+06 - - - 0.5377 - 1.416 0.148 - 109.9 1 2 0 0.0004 8 0 0 0 3.76E+07 8.09E+08 - - - 1.183 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.14317.14317.2 0.00579 16-Sep R.LLTYNSLYK[136.11].K "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1121.6212 1.06 2329 14317 2 1121.623027 561.8179 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 8.5 3072.7 - 1.10E+06 - - - 1.6191 - 2.056 0.403 - 204.1 1 2 0 0.0018 9 0 0 0 3.69E+07 3.48E+07 - - - 4.1022 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.14323.14323.2 0.0205 18-Oct K.LPAVVTADLR.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1053.6182 1.98 2334 14323 2 1053.620057 527.8164 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.84 3073.4 - 208209 - - - 1.7198 - 2.039 0.287 - 257.3 1 2 0 0.0018 10 0 0 0 4.67E+07 2.36E+07 - - - 3.1489 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.14326.14326.2 0.00165 16-Sep R.LLTYNSLYK.K "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1113.607 1.06 2335 14326 2 1113.608423 557.8108 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 8.5 3073.8 - 1.00E+06 - - - 1.268 - 1.861 0.372 - 183.5 1 2 0 0.0014 9 0 0 0 3.69E+07 3.48E+07 - - - 3.5851 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.14333.14333.2 0.00232 16-Sep R.VLGVLEVSR.S "sp|Q9H0C8|ILKAP_HUMAN,tr|F8SNU7|F8SNU7_HUMAN,tr|H7C2I8|H7C2I8_HUMAN" 3 970.5811 3.6 2340 14333 2 970.581582 486.2978 Integrin-linked kinase-associated serine\threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1 5.97 3074.6 - 940468 - - - 0.4647 - 1.73 0.403 - 214.8 1 2 0 0.0005 9 0 0 0 4.35E+07 1.21E+07 - - - 3.6032 0.8746 230117_WJC_METTL3_WT_vs_EV_F01.14338.14338.2 15.4 12-Jul K.YPLLISR.L "sp|Q92974|ARHG2_HUMAN,tr|A0A5F9ZI21|A0A5F9ZI21_HUMAN,tr|V9GYM8|V9GYM8_HUMAN" 3 860.512 1.08 2343 14338 2 860.508571 431.2633 Rho guanine nucleotide exchange factor 2 OS=Homo sapiens OX=9606 GN=ARHGEF2 PE=1 SV=4 8.75 3075.2 - 780494 - - - -3.9721 - 1.326 0.094 - 138 1 2 0 -0.0034 7 0 0 0 6.25E+07 5.80E+07 - - - 0.6283 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.14340.14340.2 0.000346 14-Sep K.VITMFVQR.Q "sp|P13010|XRCC5_HUMAN,tr|C9JZ81|C9JZ81_HUMAN,tr|H7C0H9|H7C0H9_HUMAN" 3 992.5477 0.82 2344 14340 2 992.549013 497.2811 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 9.72 3075.6 - 550325 - - - 1.3007 - 1.979 0.405 - 260.9 1 2 0 0.0013 8 0 0 0 1.19E+08 1.45E+08 - - - 4.0906 0.9959 230117_WJC_METTL3_WT_vs_EV_F01.14342.14342.2 0.0344 16-Sep K.VLPLEEAYR[166.11].F sp|Q9H223|EHD4_HUMAN 1 1098.5949 2.49 2346 14342 2 1098.593444 550.3047 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 3075.7 - 1.33E+06 - - - -1.3071 - 1.459 0.276 - 354.3 1 2 0 -0.0014 9 0 0 0 1.24E+08 4.98E+07 - - - 2.1719 0.9917 230117_WJC_METTL3_WT_vs_EV_F01.14349.14349.2 0.452 12-Jul K.LLDLLVK.F "sp|O15050|TRNK1_HUMAN,sp|Q6P2Q9|PRP8_HUMAN,tr|A0A2R8YEM9|A0A2R8YEM9_HUMAN,tr|A0A2R8Y8A3|A0A2R8Y8A3_HUMAN" 4 812.5371 2.27 2350 14349 2 812.538524 407.2758 TPR and ankyrin repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=TRANK1 PE=2 SV=4 5.84 3076.7 - 985579 - - - 1.7021 - 1.542 0.047 - 109.8 2 2 0 0.0014 7 0 0 0 5.12E+07 2.26E+07 - - - 0.6255 0.9962 230117_WJC_METTL3_WT_vs_EV_F01.14362.14362.2 0.115 14-Jul K.VLLSALER.L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 899.544 2.27 2358 14362 2 899.546473 450.7793 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.97 3078.2 - 1.53E+06 - - - 2.7303 - 1.434 0.192 - 165.3 1 2 0 0.0025 8 0 0 0 5.82E+08 2.57E+08 - - - 1.5455 0.9948 230117_WJC_METTL3_WT_vs_EV_F01.14364.14364.2 0.367 14-Jun K.VLLSALER[166.11].L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 909.5523 2.5 2359 14364 2 909.553232 455.7834 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.97 3078.4 - 788209 - - - 1.039 - 1.292 0.156 - 96.9 1 2 0 0.0009 8 0 0 0 5.79E+08 2.31E+08 - - - 0.9656 0.9235 230117_WJC_METTL3_WT_vs_EV_F01.14366.14366.2 6.38 12-Jun K.LWNGLVK[136.11].V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 836.5 1.01 2361 14366 2 836.501685 419.2573 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 3078.7 - 1.12E+06 - - - 2.0454 - 1.135 0.025 - 63.9 9 2 0 0.0017 7 0 0 0 7.87E+07 7.83E+07 - - - -0.7999 0.8857 230117_WJC_METTL3_WT_vs_EV_F01.14386.14386.2 0.111 12-Aug S.VGAEIQR.L tr|D6RFZ9|D6RFZ9_HUMAN 1 771.4239 1.04 2373 14386 2 771.424678 386.7192 Receptor of-activated protein C kinase 1 (Fragment) OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=8 5.97 3081.1 - 335471 - - - 1.0059 - 1.436 0.236 - 192.3 1 1 0 0.0008 7 0 0 0 1.92E+07 1.85E+07 - - - 1.9304 0.9958 230117_WJC_METTL3_WT_vs_EV_F01.14389.14389.2 3.51 14-Jul K.VLETFLAK.S "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 919.5379 1.6 2374 14389 2 919.53973 460.7762 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 5.97 3081.5 - 809749 - - - 2.0238 - 1.302 0.185 - 142.2 1 2 0 0.0019 8 0 0 0 8.36E+07 5.23E+07 - - - 1.2027 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.14395.14395.2 6.39 12-Jul K.ALDLLDR.M "sp|P27361|MK03_HUMAN,sp|Q99759|M3K3_HUMAN,tr|H0YEX6|H0YEX6_HUMAN,tr|J3KRN4|J3KRN4_HUMAN,tr|J3QRB6|J3QRB6_HUMAN,tr|B3KR49|B3KR49_HUMAN,tr|E9PQW4|E9PQW4_HUMAN,tr|E9PRH7|E9PRH7_HUMAN,tr|E9PBK7|E9PBK7_HUMAN" 9 814.4549 0.87 2378 14395 2 814.45687 408.2347 Mitogen-activated protein kinase 3 OS=Homo sapiens OX=9606 GN=MAPK3 PE=1 SV=4 4.21 3082.3 - 1.32E+06 - - - 2.4581 - 1.516 0.1 - 160.3 1 2 0 0.002 7 0 0 0 3.11E+07 3.59E+07 - - - 1.0973 0.997 230117_WJC_METTL3_WT_vs_EV_F01.14396.14396.2 0.188 16-Oct R.LAEYYGLYR[166.11].D sp|Q96DV4|RM38_HUMAN 1 1156.5792 1.12 2379 14396 2 1156.582948 579.2969 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3082.4 - 309677 - - - 3.2147 - 1.804 0.171 - 370.1 1 2 0 0.0037 9 0 0 0 4.88E+07 4.37E+07 - - - 2.0098 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.14400.14400.2 0.034 16-Nov K.LNSLAIGLR.Q sp|P54886|P5CS_HUMAN 1 955.5815 1.57 2381 14400 2 955.584221 478.798 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3082.9 - 843918 - - - 2.8841 - 2.283 0.346 - 332.7 1 2 0 0.0028 9 0 0 0 6.87E+07 4.38E+07 - - - 3.9839 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.14401.14401.2 0.00184 14-Aug K.VITMFVQR[166.11].Q "sp|P13010|XRCC5_HUMAN,tr|C9JZ81|C9JZ81_HUMAN,tr|H7C0H9|H7C0H9_HUMAN" 3 1002.556 0.77 2382 14401 2 1002.560058 502.2853 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 9.72 3083 - 4.26E+06 - - - 4.0556 - 1.912 0.407 - 182.5 1 2 0 0.0041 8 0 0 0 1.22E+08 1.57E+08 - - - 4.0006 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.14403.14403.2 0.00924 16-Oct R.LAEYYGLYR.D sp|Q96DV4|RM38_HUMAN 1 1146.571 1.12 2384 14403 2 1146.573724 574.2928 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3083.2 - 531007 - - - 2.4107 - 2.094 0.302 - 437.4 1 2 0 0.0028 9 0 0 0 4.88E+07 4.37E+07 - - - 3.4089 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.14406.14406.2 0.0655 12-Aug K.LWNGLVK.V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 828.4858 1.02 2385 14406 2 828.486736 415.2502 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 3083.6 - 3.33E+06 - - - 1.1612 - 1.603 0.269 - 180.5 1 2 0 0.001 7 0 0 0 8.01E+07 7.84E+07 - - - 2.5227 0.9799 230117_WJC_METTL3_WT_vs_EV_F01.14407.14407.2 13 12-Jul K.RIYGGFK[136.11].S sp|Q14520|HABP2_HUMAN 1 847.4796 - 2386 14407 2 847.480043 424.7471 Hyaluronan-binding protein 2 OS=Homo sapiens OX=9606 GN=HABP2 PE=1 SV=1 9.99 3083.7 - 799792 - - - 0.5546 - 1.316 0.024 - 126.7 1 2 0 0.0005 7 0 0 0 - - - - - 0.0882 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.14414.14414.2 0.0354 16-Oct K.LNSLAIGLR[166.11].Q sp|P54886|P5CS_HUMAN 1 965.5897 1.59 2391 14414 2 965.592878 483.8021 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3084.6 - 974470 - - - 3.255 - 2.326 0.35 - 330.7 1 2 0 0.0031 9 0 0 0 6.95E+07 4.38E+07 - - - 4.0673 0.996 230117_WJC_METTL3_WT_vs_EV_F01.14423.14423.2 0.00273 16-Oct R.ILALDC[160.03]GLK[136.11].Y "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1009.5722 2.33 2396 14423 2 1009.57724 505.7934 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.83 3085.8 - 893246 - - - 5.0388 - 1.838 0.308 - 237.7 1 2 0 0.0051 9 0 0 0 1.46E+08 6.26E+07 - - - 3.0752 0.999 230117_WJC_METTL3_WT_vs_EV_F01.14427.14427.2 0.00421 28-Nov R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 0.27 2398 14427 2 1410.786104 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3086.2 - 227165 - - - 2.1449 - 1.607 0.311 - 162.3 1 2 0 0.003 15 0 0 0 8.22E+06 3.10E+07 - - - 2.5034 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.14431.14431.2 0.0446 16-Jul R.ILALDC[160.03]GLK.Y "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1001.558 1.67 2400 14431 2 1001.5587 501.7863 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.83 3086.7 - 1.58E+06 - - - 0.7458 - 1.727 0.233 - 92.6 1 2 0 0.0007 9 0 0 0 1.59E+08 9.53E+07 - - - 2.3424 0.998 230117_WJC_METTL3_WT_vs_EV_F01.14439.14439.2 0.0799 12-Jul R.LWEAGWK[136.11].Q sp|Q9H0D6|XRN2_HUMAN 1 896.4636 0.92 2403 14439 2 896.464485 449.2391 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 6 3087.7 - 1.09E+07 - - - 1.0006 - 1.431 0.21 - 211.4 1 2 0 0.0009 7 0 0 0 3.01E+08 3.26E+08 - - - 1.7273 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.14446.14446.2 0.013 12-Jul R.LWEAGWK.Q sp|Q9H0D6|XRN2_HUMAN 1 888.4494 0.92 2407 14446 2 888.450472 445.232 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 6 3088.6 - 8.20E+06 - - - 1.2201 - 1.351 0.358 - 220.8 1 2 0 0.0011 7 0 0 0 3.00E+08 3.26E+08 - - - 2.6381 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.14454.14454.2 0.224 12-Aug K.LSAFAFK.Q sp|O75717|WDHD1_HUMAN 1 782.4327 1.53 2411 14454 2 782.433631 392.2236 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 8.75 3089.6 - 954500 - - - 1.2206 - 1.594 0.208 - 171.2 1 2 0 0.001 7 0 0 0 2.42E+07 1.58E+07 - - - 2.0543 1 230117_WJC_METTL3_WT_vs_EV_F01.14464.14464.2 0.00328 20-Nov K.DAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1160.5561 42.83 2417 14464 2 1160.559597 581.2853 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.92 3090.8 - 238733 - - - 3.0149 - 2.436 0.454 - 476.2 1 2 0 0.0035 11 0 0 0 1.02E+07 2.37E+05 - - - 4.8018 0.9914 230117_WJC_METTL3_WT_vs_EV_F01.14472.14472.2 0.238 14-Aug K.ALYPVIPR[166.11].D sp|Q8TCS8|PNPT1_HUMAN 1 937.5625 2.36 2423 14472 2 937.562075 469.7885 "Polyribonucleotide nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PNPT1 PE=1 SV=2" 8.79 3091.8 - 533163 - - - -0.4085 - 1.353 0.147 - 229.2 1 2 0 -0.0004 8 0 0 0 5.56E+07 2.36E+07 - - - 1.0384 0.997 230117_WJC_METTL3_WT_vs_EV_F01.14473.14473.2 0.0115 18-Aug K.IMLVEPPVAK[136.11].V sp|P18583|SON_HUMAN 1 1103.6504 1.61 2424 14473 2 1103.652837 552.8325 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3091.9 - 263347 - - - 2.2054 - 1.665 0.142 - 113.7 1 2 0 0.0024 10 0 0 0 1.91E+07 1.19E+07 - - - 1.5121 0.9809 230117_WJC_METTL3_WT_vs_EV_F01.14477.14477.2 1.33 12-Jul R.VLGLLER.S "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 798.4963 1.45 2426 14477 2 798.499292 400.2554 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 5.97 3092.4 - 2.21E+06 - - - 3.6982 - 1.557 0.06 - 172.8 2 2 0 0.003 7 0 0 0 5.26E+07 3.62E+07 - - - 0.7517 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.14479.14479.2 0.00228 18-Sep K.LPAVVTADLR[166.11].L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1063.6265 2.07 2428 14479 2 1063.629455 532.8205 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.84 3092.6 - 845005 - - - 2.7641 - 1.721 0.347 - 237.3 1 2 0 0.0029 10 0 0 0 6.28E+07 3.03E+07 - - - 3.1184 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.14482.14482.2 0.3 16-Jul R.AYALAFAER[166.11].G "sp|P51659|DHB4_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HLJ0|A0A804HLJ0_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HKT2|A0A804HKT2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN,tr|A0A2R8YEG2|A0A2R8YEG2_HUMAN" 12 1020.5268 2.2 2431 14482 2 1020.525158 511.2707 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6.05 3092.9 - 270962 - - - -1.61 - 1.549 0.266 - 175.4 1 2 0 -0.0016 9 0 0 0 1.89E+07 8.59E+06 - - - 2.2712 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.14483.14483.2 0.00463 22-Jul K.SPILVATAVAAR.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1167.6976 1.11 2432 14483 2 1167.698919 584.8561 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3093.1 - 133642 - - - 1.1655 - 1.664 0.138 - 95.8 1 2 0 0.0014 12 0 0 0 5.75E+08 5.17E+08 - - - 1.3997 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.14485.14485.2 0.000172 18-Aug K.LFPGSPAIYK.L "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|F8W705|F8W705_HUMAN,tr|C9JF75|C9JF75_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|C9J6W1|C9J6W1_HUMAN,tr|H0YBN8|H0YBN8_HUMAN,tr|C9J1W9|C9J1W9_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 17 1091.6015 3.16 2433 14485 2 1091.60342 546.808 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 8.59 3093.3 - 513354 - - - 1.7296 - 1.453 0.387 - 158.5 1 2 0 0.0019 10 0 0 0 6.86E+07 2.17E+07 - - - 2.9417 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.14490.14490.2 0.102 20-Jun K.LIPGPLSPVAR[166.11].G sp|P48634|PRC2A_HUMAN 1 1128.6894 1.29 2437 14490 2 1128.693426 565.352 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3093.9 - 73438.2 - - - 3.5236 - 1.457 0.241 - 71.9 1 2 0 0.004 11 0 0 0 5.16E+08 4.01E+08 - - - 1.838 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.14494.14494.2 0.000824 18-Dec R.IATANMLGIR[166.11].K sp|Q9NX20|RM16_HUMAN 1 1068.5989 1.21 2439 14494 2 1068.601078 535.3067 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3094.4 - 600114 - - - 2.0195 - 1.957 0.401 - 459.2 1 2 0 0.0022 10 0 0 0 4.43E+07 3.66E+07 - - - 3.8762 0.9792 230117_WJC_METTL3_WT_vs_EV_F01.14495.14495.2 1.05 16-Oct R.AGVIFPVGR[166.11].L "sp|Q9P0M6|H2AW_HUMAN,sp|O75367|H2AY_HUMAN,tr|A0A7I2YQD6|A0A7I2YQD6_HUMAN,tr|B4DJC3|B4DJC3_HUMAN,tr|A0A7I2V412|A0A7I2V412_HUMAN,tr|Q5SQT3|Q5SQT3_HUMAN,tr|A0A7I2V423|A0A7I2V423_HUMAN,tr|A0A7I2V2N7|A0A7I2V2N7_HUMAN,tr|A0A7I2V4D9|A0A7I2V4D9_HUMAN,tr|D6RCF2|D6RCF2_HUMAN,tr|A0A7I2V6E9|A0A7I2V6E9_HUMAN,tr|A0A7I2YQB9|A0A7I2YQB9_HUMAN,tr|A0A7I2YQR8|A0A7I2YQR8_HUMAN" 13 924.5421 2.09 2440 14495 2 924.544721 463.2783 Core histone macro-H2A.2 OS=Homo sapiens OX=9606 GN=MACROH2A2 PE=1 SV=3 9.79 3094.5 - 807659 - - - 2.8814 - 1.446 0.03 - 346.1 1 2 0 0.0027 9 0 0 0 1.17E+08 5.59E+07 - - - 0.3287 1 230117_WJC_METTL3_WT_vs_EV_F01.14496.14496.2 0.000235 18-Nov R.IATANMLGIR.K sp|Q9NX20|RM16_HUMAN 1 1058.5907 1.14 2441 14496 2 1058.594022 530.3026 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3094.7 - 544095 - - - 3.1854 - 2.492 0.437 - 390.4 1 2 0 0.0034 10 0 0 0 4.52E+07 3.97E+07 - - - 4.8163 0.9935 230117_WJC_METTL3_WT_vs_EV_F01.14498.14498.2 0.197 16-Aug K.EVLVLTSVR.N sp|Q13371|PHLP_HUMAN 1 1014.6073 0.3 2443 14498 2 1014.611452 508.3109 Phosducin-like protein OS=Homo sapiens OX=9606 GN=PDCL PE=1 SV=3 6.1 3094.9 - 283599 - - - 4.0469 - 1.471 0.225 - 130.2 1 2 0 0.0041 9 0 0 0 5.47E+06 1.83E+07 - - - 1.8181 0.8658 230117_WJC_METTL3_WT_vs_EV_F01.14504.14504.2 12.6 12-Jun R.VVVDLLK[136.11].L "sp|O95714|HERC2_HUMAN,tr|A0A3B3IRP6|A0A3B3IRP6_HUMAN,tr|A0A0J9YVP0|A0A0J9YVP0_HUMAN" 3 792.52 1.21 2447 14504 2 792.521461 397.2673 E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens OX=9606 GN=HERC2 PE=1 SV=2 5.81 3095.6 - 660712 - - - 1.7918 - 0.95 0.004 - 78.9 2 2 0 0.0014 7 0 0 0 6.08E+06 5.03E+06 - - - -1.2269 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.14511.14511.2 0.00126 16-Oct K.TLAIELAPR[166.11].N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 992.5894 1.29 2452 14511 2 992.591579 497.302 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3096.4 - 1.18E+06 - - - 2.1943 - 1.844 0.428 - 359.5 1 2 0 0.0022 9 0 0 0 1.91E+09 1.48E+09 - - - 3.9719 0.9639 230117_WJC_METTL3_WT_vs_EV_F01.14512.14512.2 0.0125 14-Oct M.PTPVILLK.E "sp|Q99832|TCPH_HUMAN,tr|A0A0D9SG95|A0A0D9SG95_HUMAN,tr|F8WBP8|F8WBP8_HUMAN" 3 879.5793 14.01 2453 14512 2 879.581132 440.7969 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 9.18 3096.5 - 1.33E+06 - - - 2.0373 - 1.896 0.341 - 329.8 1 1 0 0.0018 8 0 0 0 9.69E+07 6.92E+06 - - - 3.4885 0.9906 230117_WJC_METTL3_WT_vs_EV_F01.14514.14514.2 0.806 12-Jul R.FLTFAER[166.11].L sp|O75691|UTP20_HUMAN 1 892.4682 0.76 2455 14514 2 892.471102 447.2414 Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3 6 3096.7 - 626290 - - - 3.2259 - 1.337 0.148 - 150.9 1 2 0 0.0029 7 0 0 0 9.12E+06 1.21E+07 - - - 1.0535 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.14523.14523.2 0.00892 16-Sep K.TLAIELAPR.N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 982.5811 1.05 2462 14523 2 982.582122 492.2978 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3097.9 - 5.67E+06 - - - 1.0086 - 1.783 0.325 - 292.6 1 2 0 0.001 9 0 0 0 1.56E+09 1.48E+09 - - - 3.1142 0.9856 230117_WJC_METTL3_WT_vs_EV_F01.14524.14524.2 1.12 12-Jul K.IGIEIIK.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 784.5058 1.24 2463 14524 2 784.507207 393.2602 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3097.9 - 3.64E+06 - - - 1.7412 - 1.523 0.001 - 112.7 2 2 0 0.0014 7 0 0 0 1.00E+07 8.09E+06 - - - 0.2464 0.9951 230117_WJC_METTL3_WT_vs_EV_F01.14525.14525.2 0.538 14-Aug K.ATALPLLK[136.11].Q sp|Q9Y2P8|RCL1_HUMAN 1 833.5466 0.67 2464 14525 2 833.548179 417.7806 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 8.8 3098 - 2.55E+06 - - - 1.9063 - 1.524 0.1 - 176.7 1 2 0 0.0016 8 0 0 0 3.10E+07 4.62E+07 - - - 1.0498 0.9936 230117_WJC_METTL3_WT_vs_EV_F01.14527.14527.2 0.565 14-Aug K.ATALPLLK.Q sp|Q9Y2P8|RCL1_HUMAN 1 825.5324 0.68 2466 14527 2 825.534179 413.7735 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 8.8 3098.2 - 1.86E+06 - - - 2.1671 - 1.496 0.089 - 191.8 1 2 0 0.0018 8 0 0 0 3.11E+07 4.57E+07 - - - 0.9126 1 230117_WJC_METTL3_WT_vs_EV_F01.14528.14528.2 0.000364 16-Oct K.MYLQAAIVR.L "sp|Q13617|CUL2_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 2 1063.5848 3.17 2467 14528 2 1063.586909 532.7997 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 8.5 3098.3 - 1.76E+06 - - - 1.9491 - 1.938 0.517 - 420.4 1 2 0 0.0021 9 0 0 0 1.46E+07 4.61E+06 - - - 4.7731 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.14529.14529.2 0.00144 18-Oct K.IMLVEPPVAK.V sp|P18583|SON_HUMAN 1 1095.6362 1.6 2468 14529 2 1095.637989 548.8254 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3098.4 - 766340 - - - 1.6301 - 2.006 0.409 - 305.5 1 2 0 0.0018 10 0 0 0 1.89E+07 1.18E+07 - - - 4.0045 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.14539.14539.2 2.80E-05 20-Oct K.LIPGPLSPVAR.G sp|P48634|PRC2A_HUMAN 1 1118.6812 1.29 2476 14539 2 1118.682392 560.3479 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3099.6 - 3.09E+06 - - - 1.0843 - 1.771 0.466 - 455.1 1 2 0 0.0012 11 0 0 0 5.17E+08 4.01E+08 - - - 4.0287 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.14540.14540.2 0.123 12-Aug R.VVEFLVK.H sp|P42773|CDN2C_HUMAN 1 832.5058 1.01 2477 14540 2 832.508193 417.2602 Cyclin-dependent kinase 4 inhibitor C OS=Homo sapiens OX=9606 GN=CDKN2C PE=1 SV=1 5.97 3099.7 - 1.98E+06 - - - 2.8252 - 1.385 0.243 - 192.3 1 2 0 0.0024 7 0 0 0 1.61E+07 1.59E+07 - - - 1.8671 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.14550.14550.2 0.131 16-Sep R.VLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 969.5859 1.42 2486 14550 2 969.589231 485.8002 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3100.8 - 1.15E+06 - - - 3.4541 - 1.95 0.252 - 207.4 1 2 0 0.0033 9 0 0 0 1.07E+09 7.53E+08 - - - 2.8333 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.14558.14558.2 0.0278 14-Aug K.VPGIFISR[166.11].M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 897.5312 0.08 2492 14558 2 897.53232 449.7729 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3101.7 - 1.63E+06 - - - 1.2947 - 1.564 0.283 - 178 1 2 0 0.0012 8 0 0 0 4.51E+07 5.31E+08 - - - 2.4797 0.9951 230117_WJC_METTL3_WT_vs_EV_F01.14565.14565.2 0.00116 18-Jul K.FMQASEDLLK[136.11].E "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 1188.594 2.38 2499 14565 2 1188.598928 595.3043 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.37 3102.6 - 202673 - - - 4.1377 - 1.296 0.352 - 37.2 3 2 0 0.0049 10 0 0 0 7.93E+06 3.33E+06 - - - 2.1499 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.14569.14569.2 0.116 12-Aug R.IAAYLFK.G "sp|Q00610|CLH1_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|J3KRF5|J3KRF5_HUMAN" 5 824.4796 1.07 2501 14569 2 824.480405 413.2471 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.59 3103.1 - 1.90E+06 - - - 0.9448 - 1.697 0.27 - 175.8 1 2 0 0.0008 7 0 0 0 3.69E+08 3.44E+08 - - - 2.7107 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.14571.14571.2 0.0218 14-Aug R.ELVITIAR[166.11].E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 923.5679 1.29 2503 14571 2 923.567767 462.7912 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3103.2 - 6.65E+06 - - - -0.1841 - 1.571 0.273 - 330.2 1 2 0 -0.0002 8 0 0 0 2.85E+08 2.22E+08 - - - 2.4197 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.14575.14575.2 5.77E-05 16-Oct R.FLAEEGFYK.F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1102.5335 1.26 2507 14575 2 1102.534227 552.274 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3103.7 - 558135 - - - 0.6485 - 1.864 0.494 - 261.6 1 2 0 0.0007 9 0 0 0 1.50E+08 1.19E+08 - - - 4.491 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.14579.14579.2 0.0102 16-Aug R.FLAEEGFYK[136.11].F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1110.5477 1.26 2509 14579 2 1110.547552 556.2811 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3104.2 - 1.08E+06 - - - -0.1441 - 1.611 0.365 - 164.3 1 2 0 -0.0002 9 0 0 0 1.50E+08 1.19E+08 - - - 3.1164 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.14580.14580.2 0.0374 20-Oct K.ILATTPSAVFR.V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1174.671 2.11 2510 14580 2 1174.673806 588.3428 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3104.3 - 872635 - - - 2.3811 - 1.681 0.321 - 305.8 1 2 0 0.0028 11 0 0 0 6.89E+07 3.27E+07 - - - 2.8161 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.14581.14581.2 0.337 20-Aug K.ILATTPSAVFR[166.11].V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1184.6793 2.11 2511 14581 2 1184.680865 593.3469 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3104.4 - 424481 - - - 1.3388 - 1.439 0.298 - 141.9 1 2 0 0.0016 11 0 0 0 6.89E+07 3.28E+07 - - - 2.2261 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.14592.14592.3 2.38E-05 Oct-48 R.LVHPGVAEVVFVK.K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1392.8129 1.66 2519 14592 3 1392.809256 465.2783 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 3105.5 - 988677 - - - -2.6321 - 2.245 0.489 - 181.9 1 2 0 -0.0037 13 0 0 0 3.39E+07 2.05E+07 - - - 6.1835 0.9947 230117_WJC_METTL3_WT_vs_EV_F01.14601.14601.2 0.121 18-Oct K.AIITALGVER.R sp|Q92616|GCN1_HUMAN 1 1041.6182 1.38 2523 14601 2 1041.615058 521.8164 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 6.05 3106.6 - 1.09E+06 - - - -3.0597 - 2.237 0.252 - 314.6 1 2 0 -0.0032 10 0 0 0 6.25E+07 4.52E+07 - - - 3.1486 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.14608.14608.2 0.0143 14-Aug K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 0.96 2526 14608 2 895.480698 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3107.5 - 1.86E+06 - - - 0.3842 - 1.412 0.31 - 173 1 2 0 0.0003 8 0 0 0 5.78E+07 6.02E+07 - - - 2.3711 0.8592 230117_WJC_METTL3_WT_vs_EV_F01.14609.14609.2 5.72 12-Jun K.ELLPEIR.E "sp|P49321|NASP_HUMAN,tr|H0YDS9|H0YDS9_HUMAN,tr|Q5T624|Q5T624_HUMAN,tr|H0YF33|H0YF33_HUMAN,tr|E9PRH9|E9PRH9_HUMAN" 5 868.5018 3.71 2527 14609 2 868.49987 435.2582 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 4.53 3107.6 - 844222 - - - -2.2429 - 1.219 0.02 - 131.2 1 2 0 -0.0019 7 0 0 0 8.93E+07 2.41E+07 - - - -0.1844 0.992 230117_WJC_METTL3_WT_vs_EV_F01.14616.14616.2 0.00723 14-Oct K.QFFVAVER[166.11].E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1004.5319 0.82 2530 14616 2 1004.528744 503.2732 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 6 3108.5 - 2.15E+06 - - - -3.1278 - 1.619 0.296 - 354.2 1 2 0 -0.0031 8 0 0 0 6.93E+07 8.48E+07 - - - 2.6794 0.9878 230117_WJC_METTL3_WT_vs_EV_F01.14622.14622.2 0.252 14-Jun R.ELVITIAR.E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 913.5597 1.29 2535 14622 2 913.558488 457.7871 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3109.2 - 987386 - - - -1.2906 - 1.389 0.157 - 199.8 1 2 0 -0.0012 8 0 0 0 2.86E+08 2.22E+08 - - - 1.1912 0.9935 230117_WJC_METTL3_WT_vs_EV_F01.14624.14624.2 0.00697 14-Aug R.IGFIEEVK.A sp|Q96P63|SPB12_HUMAN 1 933.5171 112.51 2536 14624 2 933.516912 467.7658 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 4.53 3109.4 - 2.54E+06 - - - -0.2378 - 1.469 0.132 - 146.1 1 2 0 -0.0002 8 0 0 0 1.82E+08 1.61E+06 - - - 1.1758 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.14632.14632.2 0.2 16-Oct R.GSPLLIGVR[166.11].S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 920.5683 1.6 2540 14632 2 920.567952 461.2914 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3110.4 - 4.00E+06 - - - -0.3476 - 2.114 0.393 - 443.8 1 2 0 -0.0003 9 0 0 0 2.45E+08 1.53E+08 - - - 4.1093 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.14643.14643.2 0.622 14-Aug R.GLVGEIIK.R "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 827.5117 1 2545 14643 2 827.51183 414.7631 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6 3111.8 - 7.35E+06 - - - 0.2127 - 1.427 0.225 - 210.4 1 2 0 0.0002 8 0 0 0 5.49E+09 5.48E+09 - - - 1.7752 1 230117_WJC_METTL3_WT_vs_EV_F01.14655.14655.3 8.91E-11 21/128 R.SDSPVPTAPTSGGPKPSTASAVPELATDPELEK.K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3232.5987 4.47 2550 14655 3 3232.600551 1078.5402 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3113.4 - 1.19E+06 - - - 0.5732 - 3.446 0.668 - 223.8 1 2 0 0.0019 33 0 0 0 2.50E+07 5.58E+06 - - - 8.8334 0.9565 230117_WJC_METTL3_WT_vs_EV_F01.14657.14657.2 0.0216 12-Jun K.ELLPEIR[166.11].E "sp|P49321|NASP_HUMAN,tr|H0YDS9|H0YDS9_HUMAN,tr|Q5T624|Q5T624_HUMAN,tr|H0YF33|H0YF33_HUMAN,tr|E9PRH9|E9PRH9_HUMAN" 5 878.5101 3.72 2552 14657 2 878.509259 440.2623 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 4.53 3113.6 - 989627 - - - -0.9436 - 1.371 0.009 - 130.6 1 2 0 -0.0008 7 0 0 0 8.92E+07 2.40E+07 - - - 0.107 0.8852 230117_WJC_METTL3_WT_vs_EV_F01.14658.14658.2 0.463 12-Sep S.PLLIGVR.S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,sp|Q9UP38|FZD1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 6 766.5065 1.5 2553 14658 2 766.507488 384.2605 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 10.18 3113.8 - 947495 - - - 1.2772 - 1.555 0.198 - 274 1 1 0 0.001 7 0 0 0 1.90E+07 1.27E+07 - - - 1.902 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.14661.14661.2 0.000897 16-Sep K.NFITAEELR.R "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1091.5611 1.64 2556 14661 2 1091.561965 546.7878 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.53 3114.2 - 437574 - - - 0.7705 - 1.875 0.45 - 231.6 1 2 0 0.0008 9 0 0 0 7.17E+06 4.38E+06 - - - 4.183 0.9947 230117_WJC_METTL3_WT_vs_EV_F01.14671.14671.2 0.15 12-Jun R.IFFVSAK[136.11].E "sp|O95140|MFN2_HUMAN,sp|Q8IWA4|MFN1_HUMAN,tr|A0A6Q8PGV8|A0A6Q8PGV8_HUMAN,tr|H7C5H5|H7C5H5_HUMAN,tr|A0A6Q8PFJ4|A0A6Q8PFJ4_HUMAN,tr|A0A6Q8PGA3|A0A6Q8PGA3_HUMAN,tr|A0A6Q8PGS9|A0A6Q8PGS9_HUMAN" 7 818.4782 0.6 2561 14671 2 818.477857 410.2464 Mitofusin-2 OS=Homo sapiens OX=9606 GN=MFN2 PE=1 SV=3 8.75 3115.4 - 666880 - - - -0.3897 - 1.37 0.185 - 94.5 1 2 0 -0.0003 7 0 0 0 1.76E+07 2.96E+07 - - - 1.4048 0.9958 230117_WJC_METTL3_WT_vs_EV_F01.14674.14674.2 0.349 12-Aug R.TLDTFLR.S sp|Q96SK2|TM209_HUMAN 1 864.4705 1.68 2562 14674 2 864.470719 433.2425 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 5.5 3115.9 - 1.71E+06 - - - 0.2325 - 1.339 0.184 - 223.1 1 2 0 0.0002 7 0 0 0 6.31E+07 3.75E+07 - - - 1.3249 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.14675.14675.2 0.00478 16-Aug K.FVGNIYTLK.C "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1053.5859 2.1 2563 14675 2 1053.587954 527.8002 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3115.9 - 1.78E+06 - - - 1.9666 - 1.357 0.326 - 153.5 1 2 0 0.0021 9 0 0 0 1.21E+08 5.78E+07 - - - 2.3314 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.14679.14679.2 0.0659 16-Jul K.EGLVMVEVR[166.11].K sp|Q7KZF4|SND1_HUMAN 1 1040.5564 63.2 2567 14679 2 1040.5575 521.2855 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.53 3116.4 - 405050 - - - 1.0706 - 1.319 0.286 - 87.8 1 2 0 0.0011 9 0 0 0 6.58E+08 1.04E+07 - - - 1.9541 0.9254 230117_WJC_METTL3_WT_vs_EV_F01.14689.14689.2 7.93 14-Jun R.GLVGEIIK[136.11].R "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 835.5259 1 2574 14689 2 835.525103 418.7702 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6 3117.4 - 1.54E+08 - - - -0.8988 - 1.145 0.055 - 98.9 2 2 0 -0.0008 8 0 0 0 5.49E+09 5.48E+09 - - - -0.2791 0.9929 230117_WJC_METTL3_WT_vs_EV_F01.14691.14691.2 0.233 14-Aug K.LITDEFVK[136.11].Q "sp|Q12816|TROP_HUMAN,sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN,tr|A0A087X070|A0A087X070_HUMAN,tr|G5E9N2|G5E9N2_HUMAN" 6 971.5419 1.17 2575 14691 2 971.541892 486.7782 Trophinin OS=Homo sapiens OX=9606 GN=TRO PE=1 SV=3 4.37 3117.6 - 4.77E+06 - - - -0.0062 - 1.324 0.151 - 149.5 1 2 0 0 8 0 0 0 3.42E+08 2.92E+08 - - - 1.0027 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.14693.14693.2 0.0123 16-Sep K.FVGNIYTLK[136.11].C "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1061.6001 2.1 2577 14693 2 1061.600362 531.8073 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3117.8 - 2.06E+06 - - - 0.2638 - 1.636 0.408 - 191.6 1 2 0 0.0003 9 0 0 0 1.21E+08 5.78E+07 - - - 3.4785 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.14694.14694.2 0.0435 16-Aug K.LVTEPLVLK[136.11].S sp|O43896|KIF1C_HUMAN 1 1018.6518 0.56 2578 14694 2 1018.653997 510.3332 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 6 3117.9 - 2.04E+06 - - - 2.1735 - 1.777 0.265 - 165.3 1 2 0 0.0022 9 0 0 0 3.57E+07 6.36E+07 - - - 2.6609 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.14702.14702.2 0.0145 16-Aug K.LVTEPLVLK.S sp|O43896|KIF1C_HUMAN 1 1010.6376 0.66 2583 14702 2 1010.638123 506.3261 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 6 3118.8 - 1.41E+06 - - - 0.5343 - 1.603 0.344 - 132 1 2 0 0.0005 9 0 0 0 3.57E+07 5.41E+07 - - - 2.9468 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.14704.14704.2 0.197 14-Aug K.LITDEFVK.Q "sp|Q12816|TROP_HUMAN,sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN,tr|A0A087X070|A0A087X070_HUMAN,tr|G5E9N2|G5E9N2_HUMAN" 6 963.5277 1.17 2584 14704 2 963.528154 482.7711 Trophinin OS=Homo sapiens OX=9606 GN=TRO PE=1 SV=3 4.37 3119 - 5.12E+06 - - - 0.4733 - 1.417 0.199 - 162.6 1 2 0 0.0005 8 0 0 0 3.42E+08 2.92E+08 - - - 1.5619 0.9536 230117_WJC_METTL3_WT_vs_EV_F01.14707.14707.2 3.83 12-May R.IVEGILK[136.11].R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 778.5044 1.09 2586 14707 2 778.504797 390.2595 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 3119.4 - 1.49E+06 - - - 0.5215 - 1.355 0.001 - 46.4 11 2 0 0.0004 7 0 0 0 2.78E+07 2.54E+07 - - - -0.4543 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.14708.14708.2 0.0242 16-Jun R.MGPNIYELR[166.11].T "sp|Q9BPW8|NIPS1_HUMAN,tr|C9JDV8|C9JDV8_HUMAN,tr|H7C2U6|H7C2U6_HUMAN" 3 1101.5516 1.59 2587 14708 2 1101.553206 551.7831 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.75 3119.5 - 449409 - - - 1.4262 - 1.279 0.27 - 64.3 1 2 0 0.0016 9 0 0 0 5.75E+07 3.62E+07 - - - 1.7466 0.9852 230117_WJC_METTL3_WT_vs_EV_F01.14715.14715.2 1.29 12-Aug R.TVYLFDR[166.11].R sp|A6NHR9|SMHD1_HUMAN 1 922.4788 0.83 2590 14715 2 922.478015 462.2467 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 5.5 3120.5 - 715427 - - - -0.838 - 1.215 0.158 - 260.1 1 2 0 -0.0008 7 0 0 0 1.88E+07 2.26E+07 - - - 0.8248 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.14734.14734.2 0.00651 18-Nov R.VVVDALSGLK[136.11].G "sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|F8WCN3|F8WCN3_HUMAN" 3 1007.6106 1.77 2600 14734 2 1007.614918 504.8126 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 5.81 3122.8 - 1.49E+06 - - - 4.2387 - 2.204 0.389 - 352.8 1 2 0 0.0043 10 0 0 0 9.92E+07 5.60E+07 - - - 4.1187 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.14746.14746.2 0.0197 14-Jul K.IIYIAPMR.S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 975.5576 1.39 2609 14746 2 975.559793 488.7861 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 3124.4 - 4.48E+06 - - - 2.29 - 1.484 0.256 - 156.3 1 2 0 0.0022 8 0 0 0 1.17E+08 8.40E+07 - - - 2.1216 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.14747.14747.2 0.205 16-Oct K.LGIIGVVNR.S "sp|O00429|DNM1L_HUMAN,tr|F8VZ52|F8VZ52_HUMAN" 2 939.5866 1.45 2610 14747 2 939.587694 470.8006 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 9.75 3124.5 - 1.94E+06 - - - 1.2165 - 1.989 0.352 - 243.1 1 2 0 0.0011 9 0 0 0 7.42E+07 5.12E+07 - - - 3.6299 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.14749.14749.2 0.00424 14-Aug R.LGYPVLVR[166.11].A "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 925.5625 2.11 2611 14749 2 925.563863 463.7885 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 8.75 3124.7 - 2.92E+06 - - - 1.518 - 1.582 0.369 - 162.4 1 2 0 0.0014 8 0 0 0 2.00E+08 9.48E+07 - - - 3.1494 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.14754.14754.2 0.0815 18-Jul K.GVAYTLLTPK[136.11].D "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1069.6263 2.13 2613 14754 2 1069.627478 535.8204 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.59 3125.5 - 682518 - - - 1.1041 - 1.35 0.309 - 90.7 1 2 0 0.0012 10 0 0 0 2.97E+07 1.39E+07 - - - 2.1606 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.14755.14755.2 0.000488 14-Jun R.EFADFEYR.K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1075.4611 1.27 2614 14755 2 1075.463723 538.7378 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3125.6 - 618194 - - - 2.4622 - 1.446 0.457 - 137 1 2 0 0.0026 8 0 0 0 1.46E+07 1.15E+07 - - - 3.5279 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.14761.14761.2 0.0104 16-Aug R.VLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 11 1028.5866 999 2618 14761 2 1028.588175 515.3006 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3126.2 - 4.60E+06 - - - 1.5215 - 1.825 0.386 - 222.9 1 2 0 0.0016 9 0 0 0 2.07E+09 0.00E+00 - - - 3.6319 0.8991 230117_WJC_METTL3_WT_vs_EV_F01.14769.14769.2 0.0584 14-Aug V.LDGGVAYR[166.11].H sp|Q8TBB1|LNX1_HUMAN 1 859.4427 0.8 2624 14769 2 859.443373 430.7286 E3 ubiquitin-protein ligase LNX OS=Homo sapiens OX=9606 GN=LNX1 PE=1 SV=1 5.84 3127.2 - 1.26E+06 - - - 0.74 - 1.618 0.22 - 165.5 1 1 0 0.0006 8 0 0 0 2.19E+07 2.73E+07 - - - 2.117 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.14775.14775.2 0.0137 14-Jun K.LTPLLSVR.E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 897.5648 0.97 2628 14775 2 897.56575 449.7897 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3127.9 - 1.35E+06 - - - 1.1108 - 1.416 0.107 - 118.3 1 2 0 0.001 8 0 0 0 2.53E+08 2.60E+08 - - - 0.88 0.9827 230117_WJC_METTL3_WT_vs_EV_F01.14778.14778.2 9.24 12-Jul K.IGIEIIK.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 784.5058 2.13 2630 14778 2 784.5063 393.2602 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3128.2 - 1.28E+06 - - - 0.5851 - 1.473 0.007 - 116.9 2 2 0 0.0005 7 0 0 0 1.65E+10 7.77E+09 - - - 0.1853 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.14779.14779.2 0.0935 14-Jul K.IIYIAPMR[166.11].S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 985.5658 1.39 2631 14779 2 985.567362 493.7902 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 3128.3 - 1.23E+06 - - - 1.5555 - 1.566 0.232 - 154.5 1 2 0 0.0015 8 0 0 0 1.17E+08 8.40E+07 - - - 2.1068 0.9384 230117_WJC_METTL3_WT_vs_EV_F01.14783.14783.2 3.1 12-Jul K.LVLILNK.S "sp|Q9BVP2|GNL3_HUMAN,sp|Q96RW7|HMCN1_HUMAN" 2 811.5531 0.93 2633 14783 2 811.55549 406.7838 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.75 3128.8 - 1.34E+06 - - - 2.9142 - 1.198 0 - 176.6 1 2 0 0.0024 7 0 0 0 5.54E+07 5.94E+07 - - - -0.3873 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.14784.14784.2 0.119 12-Aug R.TMLLLSR[166.11].S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 842.4923 1.91 2634 14784 2 842.494154 422.2534 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.41 3128.9 - 914437 - - - 2.1662 - 1.619 0.246 - 242.4 1 2 0 0.0018 7 0 0 0 1.01E+08 5.27E+07 - - - 2.384 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.14788.14788.2 0.00433 14-Jun R.EFADFEYR[166.11].K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1085.4693 1.27 2637 14788 2 1085.468709 543.7419 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3129.3 - 599995 - - - -0.5859 - 1.494 0.443 - 130.9 1 2 0 -0.0006 8 0 0 0 1.46E+07 1.15E+07 - - - 3.5236 0.9901 230117_WJC_METTL3_WT_vs_EV_F01.14790.14790.2 1.89 12-Apr R.TMLLLSR.S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 832.4841 1.88 2638 14790 2 832.485498 417.2493 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.41 3129.5 - 3.21E+06 - - - 1.7286 - 1.141 0.141 - 77.8 1 2 0 0.0014 7 0 0 0 9.99E+07 5.30E+07 - - - 0.4999 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.14797.14797.2 0.013 12-Jul K.VTFLITR[166.11].L "sp|A6ZKI3|RTL8C_HUMAN,sp|Q9BWD3|RTL8A_HUMAN,sp|Q17RB0|RTL8B_HUMAN" 3 858.5203 1.98 2643 14797 2 858.523017 430.2674 Retrotransposon Gag-like protein 8C OS=Homo sapiens OX=9606 GN=RTL8C PE=1 SV=1 9.72 3130.4 - 756728 - - - 3.2125 - 1.416 0.288 - 195.9 1 2 0 0.0028 7 0 0 0 6.52E+07 3.29E+07 - - - 2.2694 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.14798.14798.2 0.0783 12-Aug R.YIELLTR.S sp|P15924|DESP_HUMAN 1 906.5175 18.13 2644 14798 2 906.518598 454.266 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 3130.4 - 4.51E+06 - - - 1.2465 - 1.452 0.227 - 261.1 1 2 0 0.0011 7 0 0 0 2.25E+08 1.24E+07 - - - 1.899 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.14799.14799.2 2.63 12-Aug K.LVLILNK[136.11].S "sp|Q9BVP2|GNL3_HUMAN,sp|Q96RW7|HMCN1_HUMAN" 2 819.5673 0.93 2645 14799 2 819.567947 410.7909 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.75 3130.5 - 2.19E+06 - - - 0.7589 - 1.774 0.132 - 241.3 1 2 0 0.0006 7 0 0 0 5.54E+07 5.94E+07 - - - 1.8321 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.14801.14801.2 0.0433 14-Jul K.LLESDYFR.Y "sp|Q96HE7|ERO1A_HUMAN,tr|G3V503|G3V503_HUMAN,tr|G3V3E6|G3V3E6_HUMAN" 3 1041.5131 2.14 2647 14801 2 1041.513968 521.7638 ERO1-like protein alpha OS=Homo sapiens OX=9606 GN=ERO1A PE=1 SV=2 4.37 3130.6 - 397779 - - - 0.8228 - 1.417 0.459 - 134.5 1 2 0 0.0009 8 0 0 0 8.59E+06 4.00E+06 - - - 3.4821 0.9873 230117_WJC_METTL3_WT_vs_EV_F01.14816.14816.2 1.69 14-Jul K.LTPLLSVR[166.11].E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 907.573 0.97 2658 14816 2 907.574194 454.7938 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3132.4 - 3.57E+06 - - - 1.2903 - 1.239 0.084 - 232.4 1 2 0 0.0012 8 0 0 0 2.53E+08 2.60E+08 - - - 0.3074 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.14817.14817.2 0.0432 12-Aug K.VSTVFWK[136.11].S sp|Q14152|EIF3A_HUMAN 1 873.484 0.48 2659 14817 2 873.48595 437.7493 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.72 3132.5 - 945137 - - - 2.2439 - 1.55 0.244 - 194.8 1 2 0 0.002 7 0 0 0 2.78E+07 5.84E+07 - - - 2.2312 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.14825.14825.2 0.00244 12-Aug K.FDLMYAK.R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 886.4259 3.25 2665 14825 2 886.426966 444.2202 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3133.4 - 3.53E+06 - - - 1.2297 - 1.632 0.375 - 198.2 1 2 0 0.0011 7 0 0 0 1.09E+09 3.36E+08 - - - 3.3624 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.14826.14826.2 0.16 18-Aug R.VLLGEGVLTK[136.11].E "sp|Q96S99|PKHF1_HUMAN,sp|Q9H8W4|PKHF2_HUMAN,tr|K7ELB8|K7ELB8_HUMAN,tr|K7EIX0|K7EIX0_HUMAN" 4 1035.6419 0.73 2666 14826 2 1035.642137 518.8282 Pleckstrin homology domain-containing family F member 1 OS=Homo sapiens OX=9606 GN=PLEKHF1 PE=1 SV=3 5.97 3133.5 - 3.69E+06 - - - 0.1835 - 1.67 0.384 - 151.8 1 2 0 0.0002 10 0 0 0 3.13E+07 4.31E+07 - - - 3.3086 0.9921 230117_WJC_METTL3_WT_vs_EV_F01.14829.14829.2 0.21 14-Jul R.LVTDLLQR[166.11].E sp|Q70UQ0|IKIP_HUMAN 1 966.5738 6.82 2669 14829 2 966.574522 484.2942 Inhibitor of nuclear factor kappa-B kinase-interacting protein OS=Homo sapiens OX=9606 GN=IKBIP PE=1 SV=1 5.84 3133.8 - 1.56E+06 - - - 0.7977 - 1.289 0.119 - 126.9 1 2 0 0.0008 8 0 0 0 7.79E+07 1.14E+07 - - - 0.6853 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.14835.14835.2 0.0121 16-Sep K.GFVTADMIR.E sp|Q9UHQ9|NB5R1_HUMAN 1 1008.5063 2.04 2675 14835 2 1008.510041 505.2604 NADH-cytochrome b5 reductase 1 OS=Homo sapiens OX=9606 GN=CYB5R1 PE=1 SV=1 5.84 3134.5 - 417303 - - - 3.758 - 1.823 0.406 - 273.6 1 2 0 0.0038 9 0 0 0 1.12E+07 5.47E+06 - - - 3.7758 0.9888 230117_WJC_METTL3_WT_vs_EV_F01.14837.14837.2 0.103 16-Jul K.TLAIELAPR.N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 982.5811 1.05 2677 14837 2 982.580711 492.2978 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3134.7 - 287566 - - - -0.4274 - 1.264 0.152 - 85.5 1 2 0 -0.0004 9 0 0 0 1.56E+09 1.49E+09 - - - 0.8413 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.14843.14843.2 0.535 12-Jul R.AVTIFIR.G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 818.5014 4.24 2681 14843 2 818.50269 410.258 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3135.5 - 6.49E+06 - - - 1.5467 - 1.42 0.127 - 226.9 1 2 0 0.0013 7 0 0 0 2.72E+09 6.43E+08 - - - 1.0897 0.9937 230117_WJC_METTL3_WT_vs_EV_F01.14844.14844.2 0.487 12-Jul R.VAFVNFR[166.11].R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 861.4736 1.1 2682 14844 2 861.475254 431.7441 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 9.72 3135.5 - 1.80E+06 - - - 1.8701 - 1.561 0.054 - 190.6 1 2 0 0.0016 7 0 0 0 1.31E+08 1.19E+08 - - - 0.8504 0.9956 230117_WJC_METTL3_WT_vs_EV_F01.14845.14845.2 1.52 12-Jun R.LLC[160.03]NFMR.Q "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN,tr|B4DEV8|B4DEV8_HUMAN" 3 952.4623 1.15 2683 14845 2 952.462936 477.2384 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.25 3135.6 - 1.06E+06 - - - 0.6908 - 1.156 0.223 - 97.2 1 2 0 0.0007 7 0 0 0 3.85E+07 3.35E+07 - - - 1.1472 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.14851.14851.2 0.0331 12-Aug R.FC[160.03]DVLLR.V "sp|Q9HBE1|PATZ1_HUMAN,tr|B1ARF3|B1ARF3_HUMAN" 2 921.4742 0.67 2687 14851 2 921.475242 461.7444 "POZ-, AT hook-, and zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=PATZ1 PE=1 SV=1" 5.83 3136.3 - 530659 - - - 1.1058 - 1.384 0.287 - 231 1 2 0 0.001 7 0 0 0 1.88E+07 2.78E+07 - - - 2.1902 0.9947 230117_WJC_METTL3_WT_vs_EV_F01.14854.14854.2 0.021 12-Aug R.VAFVNFR.R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 851.4654 1.1 2688 14854 2 851.465849 426.74 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 9.72 3136.7 - 3.14E+06 - - - 0.559 - 1.577 0.074 - 280.2 1 2 0 0.0005 7 0 0 0 1.31E+08 1.18E+08 - - - 1.0308 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.14863.14863.2 0.00965 12-Jun K.FDLMYAK[136.11].R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 894.4401 3.25 2690 14863 2 894.441324 448.2273 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3138.1 - 6.15E+06 - - - 1.3953 - 1.432 0.23 - 105.6 1 2 0 0.0012 7 0 0 0 1.09E+09 3.36E+08 - - - 1.8771 0.9764 230117_WJC_METTL3_WT_vs_EV_F01.14879.14879.2 1.87 12-Jul R.ELFVMAR[166.11].E "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QSA9|J3QSA9_HUMAN" 4 874.461 6.04 2702 14879 2 874.460632 438.2378 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 6.1 3140 - 1.13E+06 - - - -0.454 - 1.451 0.014 - 224.5 1 2 0 -0.0004 7 0 0 0 2.11E+08 3.49E+07 - - - 0.3238 0.9586 230117_WJC_METTL3_WT_vs_EV_F01.14880.14880.2 0.76 16-Jun K.LISYSYMVR[166.11].G sp|P07099|HYEP_HUMAN 1 1140.5877 1.01 2703 14880 2 1140.591815 571.3011 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 8.59 3140.1 - 221695 - - - 3.6201 - 1.054 0.132 - 86.3 1 2 0 0.0041 9 0 0 0 2.09E+07 2.08E+07 - - - 0.1668 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.14884.14884.2 0.00815 16-Aug K.IPFASLASR.L sp|P35573|GDE_HUMAN 1 960.5393 0.28 2705 14884 2 960.538799 481.2769 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3140.6 - 1.65E+06 - - - -0.4862 - 1.542 0.303 - 168.7 1 2 0 -0.0005 9 0 0 0 3.23E+07 1.15E+08 - - - 2.5317 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.14888.14888.2 4.10E-05 22-Nov K.FAQALGLTEAVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1246.6921 0.86 2709 14888 2 1246.69086 624.3533 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3141.1 - 552364 - - - -1.0251 - 1.43 0.495 - 216.6 1 2 0 -0.0013 12 0 0 0 2.76E+07 3.22E+07 - - - 3.6378 1 230117_WJC_METTL3_WT_vs_EV_F01.14889.14889.2 8.99E-09 13/22 K.FAQALGLTEAVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1254.7063 0.86 2710 14889 2 1254.703384 628.3604 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3141.3 - 528208 - - - -2.3543 - 2.661 0.564 - 574.2 1 2 0 -0.003 12 0 0 0 2.76E+07 3.22E+07 - - - 5.7809 0.9926 230117_WJC_METTL3_WT_vs_EV_F01.14893.14893.2 0.0631 14-Sep R.LYELDGLR[166.11].E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 987.5265 2.87 2712 14893 2 987.523103 494.7705 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3141.8 - 659094 - - - -3.4055 - 1.76 0.303 - 298.2 1 2 0 -0.0034 8 0 0 0 7.62E+08 2.65E+08 - - - 2.9829 0.9659 230117_WJC_METTL3_WT_vs_EV_F01.14896.14896.2 6.67 12-May R.AVTIFIR[166.11].G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 828.5097 4.24 2714 14896 2 828.509375 415.2621 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3142 - 1.27E+07 - - - -0.385 - 1.213 0.071 - 104.5 2 2 0 -0.0003 7 0 0 0 2.72E+09 6.43E+08 - - - 0.0427 0.9908 230117_WJC_METTL3_WT_vs_EV_F01.14910.14910.2 0.244 12-Jul R.FLSEMLK.S sp|P15924|DESP_HUMAN 1 866.4572 11.36 2722 14910 2 866.455388 434.2359 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 3143.7 - 4.30E+06 - - - -2.0636 - 1.394 0.238 - 126.4 1 2 0 -0.0018 7 0 0 0 1.47E+08 1.29E+07 - - - 1.8508 0.9935 230117_WJC_METTL3_WT_vs_EV_F01.14918.14918.2 0.201 14-Aug R.LIEILSEK.A "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 943.559 2.16 2724 14918 2 943.559838 472.7868 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 3144.9 - 1.59E+06 - - - 0.8892 - 1.402 0.102 - 136.1 1 2 0 0.0008 8 0 0 0 5.23E+07 2.42E+07 - - - 0.8132 0.9874 230117_WJC_METTL3_WT_vs_EV_F01.14927.14927.2 0.0735 12-Jun R.IVFQEFR[166.11].Q "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN" 2 947.5104 0.78 2728 14927 2 947.508635 474.7625 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3146.1 - 1.30E+06 - - - -1.886 - 1.326 0.209 - 133.9 1 2 0 -0.0018 7 0 0 0 2.14E+08 2.73E+08 - - - 1.4782 0.8647 230117_WJC_METTL3_WT_vs_EV_F01.14933.14933.2 1.86 12-Jun K.YLPDIIK.D sp|O15355|PPM1G_HUMAN 1 860.5008 3.48 2730 14933 2 860.498862 431.2577 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 5.83 3146.8 - 2.06E+06 - - - -2.1999 - 0.923 0.141 - 117.7 1 2 0 -0.0019 7 0 0 0 2.44E+08 7.02E+07 - - - -0.1721 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.14936.14936.2 0.00987 14-Aug R.DAFVYAIK.N "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 925.4909 0.96 2731 14936 2 925.489816 463.7527 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 5.83 3147.2 - 2.95E+06 - - - -1.1918 - 1.655 0.352 - 271.7 1 2 0 -0.0011 8 0 0 0 1.78E+08 1.85E+08 - - - 3.16 0.8616 230117_WJC_METTL3_WT_vs_EV_F01.14938.14938.2 0.00247 14-Oct R.YPDGIISK.P sp|Q86U44|MTA70_HUMAN 1 891.4702 11.95 2732 14938 2 891.46851 446.7424 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3147.5 - 2.64E+06 - - - -1.8767 - 1.67 0.39 - 271.1 1 1 0 -0.0017 8 0 0 0 2.30E+08 1.92E+07 - - - 3.4677 0.9927 230117_WJC_METTL3_WT_vs_EV_F01.14952.14952.2 0.0699 16-Sep K.LFVQDLATR[166.11].V sp|P33176|KINH_HUMAN 1 1071.5952 2.02 2737 14952 2 1071.593393 536.8049 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 5.84 3149.3 - 602093 - - - -1.7003 - 1.659 0.183 - 287.7 1 2 0 -0.0018 9 0 0 0 3.78E+07 1.87E+07 - - - 1.8566 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.14960.14960.2 0.0042 18-Sep K.AYAALAALEK[136.11].L sp|Q12906|ILF3_HUMAN 1 1027.5793 13.99 2739 14960 2 1027.577001 514.7969 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.05 3150.5 - 417155 - - - -2.283 - 1.731 0.442 - 217.4 1 2 0 -0.0023 10 0 0 0 3.24E+08 2.32E+07 - - - 3.8365 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.14964.14964.2 0.0207 18-Sep R.INEILSNALK.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 3 1113.6394 3 2741 14964 2 1113.6395 557.827 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3150.9 - 1.37E+06 - - - 0.1131 - 1.77 0.244 - 207.3 1 2 0 0.0001 10 0 0 0 2.69E+07 8.94E+06 - - - 2.4369 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.14966.14966.2 0.000978 20-Nov K.ILQLVATGAVR.D "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A1B0GTT3|A0A1B0GTT3_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQQ5|A0A0U1RQQ5_HUMAN" 6 1139.7026 1.91 2742 14966 2 1139.701395 570.8586 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 9.75 3151.1 - 774466 - - - -1.095 - 2.003 0.341 - 359.6 1 2 0 -0.0012 11 0 0 0 1.80E+07 9.39E+06 - - - 3.4384 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.14975.14975.2 0.059 12-Jul K.LGFEEFK[136.11].Y "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 876.4473 2.62 2748 14975 2 876.449771 439.2309 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 3152.1 - 1.06E+06 - - - 2.8536 - 1.555 0.164 - 131.7 1 2 0 0.0025 7 0 0 0 2.95E+08 1.13E+08 - - - 1.6504 0.9727 230117_WJC_METTL3_WT_vs_EV_F01.14978.14978.2 4.52 12-Jul K.LGFEEFK.Y "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 868.4331 2.62 2749 14978 2 868.432142 435.2238 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 3152.5 - 3.48E+06 - - - -1.0686 - 1.144 0.138 - 142.2 1 2 0 -0.0009 7 0 0 0 2.96E+08 1.13E+08 - - - 0.4862 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.14983.14983.2 4.80E-06 16-Sep R.AFSYYGPLR[166.11].T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1082.5425 0.9 2751 14983 2 1082.541978 542.2785 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3153.1 - 931497 - - - -0.4369 - 1.823 0.355 - 363.7 1 2 0 -0.0005 9 0 0 0 3.41E+08 3.78E+08 - - - 3.4001 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.14987.14987.2 0.00123 16-Sep R.AFSYYGPLR.T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1072.5342 0.9 2754 14987 2 1072.537088 537.2744 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3153.5 - 1.43E+06 - - - 2.7104 - 1.702 0.459 - 272.6 1 2 0 0.0029 9 0 0 0 3.41E+08 3.78E+08 - - - 3.9688 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.14994.14994.2 0.0108 20-Oct K.LVLLGESAVGK[136.11].S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1092.6634 1.54 2758 14994 2 1092.663209 547.339 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3154.4 - 1.87E+06 - - - -0.1849 - 2.142 0.334 - 294.6 1 2 0 -0.0002 11 0 0 0 1.52E+08 9.85E+07 - - - 3.5685 0.999 230117_WJC_METTL3_WT_vs_EV_F01.14998.14998.2 0.0148 20-Sep K.LVLLGESAVGK.S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1084.6492 1.55 2759 14998 2 1084.648908 543.3319 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3155 - 1.47E+06 - - - -0.2794 - 1.855 0.305 - 218.2 1 2 0 -0.0003 11 0 0 0 1.52E+08 9.85E+07 - - - 2.9652 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.15004.15004.2 0.321 12-Aug K.YNIMLVR.L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 907.495 7.86 2763 15004 2 907.492669 454.7548 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3155.6 - 640664 - - - -2.5223 - 1.666 0.307 - 291.9 1 2 0 -0.0023 7 0 0 0 1.82E+09 2.31E+08 - - - 2.9251 0.9867 230117_WJC_METTL3_WT_vs_EV_F01.15016.15016.2 0.109 16-Jun R.LEPLYSPIR[166.11].S sp|Q9UBB9|TFP11_HUMAN 1 1096.6156 1.15 2769 15016 2 1096.614631 549.3151 Tuftelin-interacting protein 11 OS=Homo sapiens OX=9606 GN=TFIP11 PE=1 SV=1 6 3157.1 - 1.39E+06 - - - -0.8982 - 1.236 0.192 - 80.4 2 2 0 -0.001 9 0 0 0 3.31E+07 2.88E+07 - - - 0.9373 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.15028.15028.2 0.0489 12-Jul K.YNIMLVR[166.11].L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 917.5032 7.86 2773 15028 2 917.502156 459.7589 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3158.7 - 1.46E+06 - - - -1.1684 - 1.541 0.273 - 193.6 1 2 0 -0.0011 7 0 0 0 1.82E+09 2.31E+08 - - - 2.4272 0.9725 230117_WJC_METTL3_WT_vs_EV_F01.15033.15033.2 0.458 12-Aug R.LNLYELK.E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 891.5066 1.78 2775 15033 2 891.504732 446.7606 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3159.4 - 1.31E+06 - - - -2.0606 - 1.391 0.115 - 188.6 1 2 0 -0.0018 7 0 0 0 1.94E+08 1.09E+08 - - - 0.9355 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.15034.15034.2 0.424 14-Jun K.IEPPGLFR.G "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|E5RJ95|E5RJ95_HUMAN,tr|E5RIC7|E5RIC7_HUMAN,tr|E5RFS0|E5RFS0_HUMAN" 5 927.5178 0.68 2776 15034 2 927.517859 464.7662 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 6 3159.5 - 911012 - - - 0.0615 - 1.131 0.266 - 106.9 1 2 0 0.0001 8 0 0 0 8.95E+07 1.31E+08 - - - 1.3769 0.9573 230117_WJC_METTL3_WT_vs_EV_F01.15038.15038.2 0.00198 16-Aug K.YLPELMAEK[136.11].D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1100.5667 1.17 2777 15038 2 1100.560132 551.2906 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3160.1 - 958131 - - - -5.9978 - 1.535 0.337 - 199.4 1 2 0 -0.0066 9 0 0 0 1.19E+08 1.02E+08 - - - 2.7678 0.986 230117_WJC_METTL3_WT_vs_EV_F01.15045.15045.2 0.19 12-Sep R.LNLYELK[136.11].E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 899.5208 1.77 2778 15045 2 899.518786 450.7677 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3161.2 - 2.52E+06 - - - -2.2045 - 1.642 0.128 - 248.1 1 2 0 -0.002 7 0 0 0 1.94E+08 1.09E+08 - - - 1.5571 0.9142 230117_WJC_METTL3_WT_vs_EV_F01.15049.15049.2 0.182 16-Sep H.VPIILVGNK.A "sp|O75628|REM1_HUMAN,sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,sp|Q8IXI1|MIRO2_HUMAN,sp|P55042|RAD_HUMAN,sp|Q9Y3L5|RAP2C_HUMAN,tr|I3L2C6|I3L2C6_HUMAN,tr|H3BST5|H3BST5_HUMAN,tr|A0A087X2C3|A0A087X2C3_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 16 951.6117 1.95 2780 15049 2 951.612146 476.8131 GTP-binding protein REM 1 OS=Homo sapiens OX=9606 GN=REM1 PE=1 SV=2 8.72 3161.7 - 1.28E+06 - - - 0.4655 - 1.673 0.252 - 249.1 1 1 0 0.0004 9 0 0 0 9.75E+07 5.00E+07 - - - 2.391 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.15051.15051.2 0.021 16-Aug K.YLPELMAEK.D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1092.5525 1.14 2781 15051 2 1092.550325 547.2835 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3161.9 - 2.21E+06 - - - -2.021 - 1.301 0.37 - 170.3 1 2 0 -0.0022 9 0 0 0 1.19E+08 1.05E+08 - - - 2.5344 0.9821 230117_WJC_METTL3_WT_vs_EV_F01.15053.15053.2 2.53 14-Jul K.IEPPGLFR[166.11].G "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|E5RJ95|E5RJ95_HUMAN,tr|E5RIC7|E5RIC7_HUMAN,tr|E5RFS0|E5RFS0_HUMAN" 5 937.5261 0.7 2783 15053 2 937.52559 469.7703 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 6 3162.1 - 2.10E+06 - - - -0.5141 - 1.224 0.139 - 151.1 2 2 0 -0.0005 8 0 0 0 9.20E+07 1.31E+08 - - - 0.5426 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.15054.15054.2 0.0606 14-Jun R.VMLYPSR[166.11]I.- sp|P18077|RL35A_HUMAN 1 987.5451 0.8 2784 15054 2 987.546084 494.7798 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.72 3162.3 - 1.35E+06 - - - 1.0035 - 1.394 0.307 - 148.4 1 2 0 0.001 8 0 0 0 6.91E+07 8.65E+07 - - - 2.31 0.8749 230117_WJC_METTL3_WT_vs_EV_F01.15058.15058.2 0.0734 16-Sep H.VPIILVGNK[136.11].A "sp|O75628|REM1_HUMAN,sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,sp|Q8IXI1|MIRO2_HUMAN,sp|P55042|RAD_HUMAN,sp|Q9Y3L5|RAP2C_HUMAN,tr|I3L2C6|I3L2C6_HUMAN,tr|H3BST5|H3BST5_HUMAN,tr|A0A087X2C3|A0A087X2C3_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 16 959.6259 1.95 2785 15058 2 959.625185 480.8202 GTP-binding protein REM 1 OS=Homo sapiens OX=9606 GN=REM1 PE=1 SV=2 8.72 3162.8 - 906583 - - - -0.7482 - 1.865 0.246 - 239.4 1 1 0 -0.0007 9 0 0 0 9.75E+07 5.00E+07 - - - 2.6609 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.15070.15070.2 0.00799 16-Sep R.ILDSAEFIK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1042.579 0.94 2791 15070 2 1042.578919 522.2968 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3164.4 - 1.52E+08 - - - -0.0892 - 1.81 0.388 - 167.1 1 2 0 -0.0001 9 0 0 0 8.53E+09 9.07E+09 - - - 3.6233 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.15078.15078.2 0.0351 14-Jun R.VMLYPSRI.- sp|P18077|RL35A_HUMAN 1 977.5368 0.8 2797 15078 2 977.537213 489.7757 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.72 3165.2 - 3.66E+06 - - - 0.399 - 1.331 0.324 - 203.8 1 2 0 0.0004 8 0 0 0 6.88E+07 8.61E+07 - - - 2.2963 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.15087.15087.2 0.00645 12-Jul K.FADFMVK.D "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 14 856.4153 1.85 2803 15087 2 856.415768 429.2149 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 5.84 3166.2 - 719665 - - - 0.5336 - 1.223 0.364 - 132.8 1 2 0 0.0005 7 0 0 0 3.06E+07 1.66E+07 - - - 2.3672 0.9941 230117_WJC_METTL3_WT_vs_EV_F01.15100.15100.2 0.00103 12-Aug K.FADFMVK[136.11].D "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 14 864.4295 1.87 2813 15100 2 864.426805 433.222 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 5.84 3167.8 - 877926 - - - -3.1304 - 1.23 0.456 - 114.9 1 2 0 -0.0027 7 0 0 0 3.06E+07 1.64E+07 - - - 3.0641 0.8934 230117_WJC_METTL3_WT_vs_EV_F01.15101.15101.2 0.613 14-Aug R.PIVTVWER[166.11].E "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EQR8|K7EQR8_HUMAN" 3 1008.5632 3.23 2814 15101 2 1008.564139 505.2889 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 6.43 3167.9 - 506525 - - - 0.9449 - 1.552 0.223 - 212.9 1 1 0 0.001 8 0 0 0 1.39E+08 4.31E+07 - - - 2.0134 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.15104.15104.2 0.0711 12-Jul K.WDPVVLK.N sp|Q9BVJ6|UT14A_HUMAN 1 855.4854 1.28 2815 15104 2 855.485712 428.75 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 5.84 3168.3 - 1.83E+06 - - - 0.3179 - 1.03 0.315 - 152.2 1 2 0 0.0003 7 0 0 0 7.64E+07 5.96E+07 - - - 1.4612 0.9695 230117_WJC_METTL3_WT_vs_EV_F01.15105.15105.2 0.259 14-Jul R.VLFGEITR[166.11].L "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 943.5366 1.43 2816 15105 2 943.534512 472.7756 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 5.97 3168.4 - 2.13E+06 - - - -2.2522 - 1.232 0.173 - 110.4 1 2 0 -0.0021 8 0 0 0 2.96E+07 2.07E+07 - - - 0.9474 0.9871 230117_WJC_METTL3_WT_vs_EV_F01.15106.15106.2 0.249 12-Jul K.WDPVVLK[136.11].N sp|Q9BVJ6|UT14A_HUMAN 1 863.4996 1.32 2817 15106 2 863.499875 432.7571 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 5.84 3168.4 - 1.15E+06 - - - 0.2721 - 1.006 0.191 - 106.3 1 2 0 0.0002 7 0 0 0 7.59E+07 5.73E+07 - - - 0.4706 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.15107.15107.2 0.12 16-Jul R.QVLDEALLR.R sp|Q6P087|RUSD3_HUMAN 1 1055.5975 1.08 2818 15107 2 1055.597786 528.806 Mitochondrial mRNA pseudouridine synthase RPUSD3 OS=Homo sapiens OX=9606 GN=RPUSD3 PE=1 SV=3 4.37 3168.6 - 351638 - - - 0.2624 - 1.249 0.315 - 81.7 1 2 0 0.0003 9 0 0 0 2.32E+06 2.15E+06 - - - 2.0108 1 230117_WJC_METTL3_WT_vs_EV_F01.15114.15114.2 9.88E-07 13/20 R.MGAGMGFGLER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1134.519 1.97 2823 15114 2 1134.515452 568.2668 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 3169.4 - 324401 - - - -3.0877 - 2.182 0.503 - 612.4 1 2 0 -0.0035 11 0 0 0 4.66E+07 2.36E+07 - - - 4.8658 0.9361 230117_WJC_METTL3_WT_vs_EV_F01.15120.15120.2 0.397 14-Jul K.LMALGPIR.L "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 869.5157 9.95 2827 15120 2 869.512642 435.7651 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 9.75 3170.1 - 752872 - - - -3.51 - 1.391 0.143 - 93.2 2 2 0 -0.0031 8 0 0 0 1.53E+07 1.54E+06 - - - 0.9571 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.15122.15122.2 0.0141 14-Sep R.LLEIVSYK.L "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 963.5641 1.11 2829 15122 2 963.568239 482.7893 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6 3170.4 - 443582 - - - 4.3121 - 1.673 0.331 - 215.3 1 2 0 0.0042 8 0 0 0 9.81E+07 8.86E+07 - - - 3.0365 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.15126.15126.2 0.0314 16-Sep R.ILDSAEFIK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1034.5648 0.93 2832 15126 2 1034.565209 518.2897 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3170.9 - 1.33E+07 - - - 0.3837 - 1.735 0.404 - 182 1 2 0 0.0004 9 0 0 0 8.41E+09 9.06E+09 - - - 3.6189 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.15128.15128.2 0.000968 14-Sep R.VGEIVVFR.L "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 917.5335 2.65 2833 15128 2 917.533959 459.774 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.97 3171.1 - 2.12E+06 - - - 0.5526 - 1.929 0.409 - 284.1 1 2 0 0.0005 8 0 0 0 6.67E+07 2.52E+07 - - - 4.0432 0.9869 230117_WJC_METTL3_WT_vs_EV_F01.15136.15136.2 0.0526 14-Jul K.LIYLVPEK.Q "sp|Q9NZM3|ITSN2_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN,tr|E7EPJ2|E7EPJ2_HUMAN" 3 973.5848 3.97 2839 15136 2 973.585982 487.7997 Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3 6 3172 - 888244 - - - 1.1946 - 1.413 0.046 - 117.5 2 2 0 0.0012 8 0 0 0 3.44E+07 8.67E+06 - - - 0.2886 1 230117_WJC_METTL3_WT_vs_EV_F01.15141.15141.2 1.84E-07 14/28 R.NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1656.8459 5.18 2844 15141 2 1656.850641 829.4302 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3172.5 - 453374 - - - 2.8597 - 2.809 0.475 - 408.3 1 2 0 0.0047 15 0 0 0 3.14E+07 6.07E+06 - - - 5.0871 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.15148.15148.2 0.0047 12-Aug K.MDLLLTK[136.11].T "sp|Q6P3W7|SCYL2_HUMAN,tr|H0YIK6|H0YIK6_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 840.487 0.88 2849 15148 2 840.487281 421.2508 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.59 3173.2 - 1.18E+06 - - - 0.3034 - 1.763 0.214 - 258.5 1 2 0 0.0003 7 0 0 0 7.43E+07 8.43E+07 - - - 2.4181 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.15149.15149.2 0.000519 14-Aug R.VWC[160.03]VASLR.G "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 989.5117 1.01 2850 15149 2 989.514183 495.7631 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 8.22 3173.3 - 719836 - - - 2.5386 - 1.809 0.407 - 236.5 1 2 0 0.0025 8 0 0 0 1.98E+07 1.96E+07 - - - 3.8341 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.15158.15158.2 3.41 12-Jul R.LIVDVIR.F "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 826.5276 1.18 2855 15158 2 826.527808 414.2711 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.84 3174.4 - 431792 - - - 0.2045 - 1.296 0.187 - 160.7 1 2 0 0.0002 7 0 0 0 8.50E+07 7.19E+07 - - - 1.2437 0.999 230117_WJC_METTL3_WT_vs_EV_F01.15166.15166.2 0.333 16-Aug R.LLLPTPTVK.Q "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 980.627 2.42 2861 15166 2 980.628976 491.3208 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 3175.4 - 383463 - - - 1.9967 - 1.454 0.317 - 166.1 1 2 0 0.002 9 0 0 0 4.43E+08 1.84E+08 - - - 2.4647 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.15171.15171.2 0.00109 16-Sep K.ELGVGIALR.K sp|Q01469|FABP5_HUMAN 1 926.5549 12.35 2864 15171 2 926.556565 464.2847 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 6.1 3175.9 - 7.09E+06 - - - 1.7797 - 1.901 0.4 - 365.7 1 2 0 0.0016 9 0 0 0 1.66E+08 1.35E+07 - - - 3.8533 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.15176.15176.2 0.00435 28-Dec R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 6.58 2869 15176 2 1646.84227 824.4261 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3176.5 - 205316 - - - 2.8157 - 2.478 0.433 - 462.7 1 2 0 0.0046 15 0 0 0 3.64E+07 5.53E+06 - - - 4.4687 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.15180.15180.2 0.0544 12-Apr K.LVPGLFK[136.11].N "sp|P35226|BMI1_HUMAN,sp|P35227|PCGF2_HUMAN,tr|Q5T8Z6|Q5T8Z6_HUMAN,tr|A0A087X259|A0A087X259_HUMAN,tr|J3KT13|J3KT13_HUMAN,tr|R4GMX3|R4GMX3_HUMAN,tr|Q5T8Z4|Q5T8Z4_HUMAN" 7 780.4989 1.41 2871 15180 2 780.499777 391.2567 Polycomb complex protein BMI-1 OS=Homo sapiens OX=9606 GN=BMI1 PE=1 SV=2 8.75 3177 - 1.81E+06 - - - 1.1095 - 0.992 0.309 - 56.3 2 2 0 0.0009 7 0 0 0 6.34E+07 4.49E+07 - - - 1.1631 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.15181.15181.2 0.00822 16-Aug K.ANPALYVLR[166.11].E sp|Q6P2Q9|PRP8_HUMAN 1 1025.5897 1.36 2872 15181 2 1025.592657 513.8021 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.79 3177.1 - 1.90E+06 - - - 2.8491 - 1.491 0.291 - 191.2 1 2 0 0.0029 9 0 0 0 1.01E+08 7.42E+07 - - - 2.345 0.998 230117_WJC_METTL3_WT_vs_EV_F01.15182.15182.2 1.23 14-Aug K.GAIEVLIR[166.11].E "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 879.5417 1.02 2873 15182 2 879.543149 440.7781 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 6 3177.1 - 1.83E+06 - - - 1.6224 - 1.737 0.142 - 193.6 1 2 0 0.0014 8 0 0 0 5.06E+07 4.97E+07 - - - 1.7547 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.15184.15184.2 0.295 16-Aug R.LLLPTPTVK[136.11].Q "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 988.6412 2.42 2875 15184 2 988.642899 495.3279 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 3177.3 - 561184 - - - 1.7003 - 1.341 0.165 - 155.4 1 2 0 0.0017 9 0 0 0 4.43E+08 1.84E+08 - - - 1.108 0.9685 230117_WJC_METTL3_WT_vs_EV_F01.15187.15187.2 1.4 14-Jul K.LLIESLEK.Y "sp|Q8TC07|TBC15_HUMAN,tr|F8VV61|F8VV61_HUMAN,tr|C9JA93|C9JA93_HUMAN" 3 943.559 2.03 2876 15187 2 943.562286 472.7868 TBC1 domain family member 15 OS=Homo sapiens OX=9606 GN=TBC1D15 PE=1 SV=2 4.53 3177.7 - 783204 - - - 3.4836 - 1.313 0.059 - 116 1 2 0 0.0033 8 0 0 0 2.85E+07 1.41E+07 - - - 0.297 0.9739 230117_WJC_METTL3_WT_vs_EV_F01.15188.15188.2 3.28 16-Jun K.ELGVGIALR[166.11].K sp|Q01469|FABP5_HUMAN 1 936.5632 19.27 2877 15188 2 936.564895 469.2889 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 6.1 3177.8 - 514663 - - - 1.8248 - 1.035 0.116 - 77.6 2 2 0 0.0017 9 0 0 0 1.49E+08 7.75E+06 - - - -0.1377 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.15197.15197.2 0.00546 14-Jun K.FLVGFTNK[136.11].G "sp|P43307|SSRA_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|C9J5W0|C9J5W0_HUMAN" 6 932.5211 1.47 2884 15197 2 932.524328 467.2678 Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3 8.75 3178.9 - 991132 - - - 3.4584 - 1.287 0.351 - 95.4 1 2 0 0.0032 8 0 0 0 2.64E+08 1.80E+08 - - - 2.3934 0.989 230117_WJC_METTL3_WT_vs_EV_F01.15198.15198.2 0.469 12-Jul K.TLLDSLR.S sp|Q5JTH9|RRP12_HUMAN 1 816.4705 0.73 2885 15198 2 816.472829 409.2425 RRP12-like protein OS=Homo sapiens OX=9606 GN=RRP12 PE=1 SV=2 5.5 3179.1 - 545133 - - - 2.8305 - 1.321 0.114 - 202.3 1 2 0 0.0023 7 0 0 0 3.97E+07 5.46E+07 - - - 0.7644 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.15204.15204.2 0.125 12-Aug R.QMSLLLR.R sp|P25705|ATPA_HUMAN 1 859.495 1.59 2889 15204 2 859.496717 430.7548 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 9.75 3179.8 - 1.11E+06 - - - 2.0466 - 1.53 0.181 - 247.8 1 2 0 0.0018 7 0 0 0 2.58E+08 1.62E+08 - - - 1.7248 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.15209.15209.2 0.0751 16-Sep K.MLLYTEVTR[166.11].Y "sp|P31150|GDIA_HUMAN,sp|P50395|GDIB_HUMAN,tr|G5E9U5|G5E9U5_HUMAN,tr|Q5SX86|Q5SX86_HUMAN,tr|Q5SX90|Q5SX90_HUMAN,tr|V9GYF8|V9GYF8_HUMAN,tr|V9GYJ7|V9GYJ7_HUMAN" 7 1134.5983 1.28 2894 15209 2 1134.600041 568.3064 Rab GDP dissociation inhibitor alpha OS=Homo sapiens OX=9606 GN=GDI1 PE=1 SV=2 5.75 3180.4 - 326810 - - - 1.5777 - 1.532 0.233 - 337.2 1 2 0 0.0018 9 0 0 0 2.73E+07 2.14E+07 - - - 1.9955 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.15219.15219.2 0.00892 16-Sep K.LVELPYTVK.G sp|Q9NPF4|OSGEP_HUMAN 1 1060.6168 2.86 2902 15219 2 1060.618793 531.3157 Probable tRNA N6-adenosine threonylcarbamoyltransferase OS=Homo sapiens OX=9606 GN=OSGEP PE=1 SV=1 6 3181.4 - 1.32E+06 - - - 1.8338 - 1.869 0.285 - 243.2 1 2 0 0.0019 9 0 0 0 3.33E+07 1.16E+07 - - - 2.9547 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.15229.15229.2 1.84E-05 16-Aug R.AFGYYGPLR[166.11].S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1052.5319 0.98 2910 15229 2 1052.53369 527.2732 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3182.4 - 1.86E+06 - - - 1.714 - 1.607 0.4 - 284.2 1 2 0 0.0018 9 0 0 0 1.22E+09 1.23E+09 - - - 3.3672 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.15230.15230.2 0.000856 16-Aug R.AFGYYGPLR.S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1042.5236 0.97 2911 15230 2 1042.525332 522.2691 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3182.4 - 1.35E+06 - - - 1.646 - 1.49 0.41 - 276 1 2 0 0.0017 9 0 0 0 1.20E+09 1.23E+09 - - - 3.2224 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.15231.15231.2 0.0141 20-Nov R.IALTDNALIAR[166.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1179.6851 0.89 2912 15231 2 1179.687246 590.8498 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3182.5 - 163476 - - - 1.8259 - 2.061 0.133 - 303.7 1 2 0 0.0022 11 0 0 0 3.26E+07 3.66E+07 - - - 1.9791 0.9962 230117_WJC_METTL3_WT_vs_EV_F01.15234.15234.2 0.0555 14-May K.NVPYVFVR.S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 992.5444 1.12 2913 15234 2 992.548014 497.2795 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3182.9 - 511929 - - - 3.6905 - 1.065 0.388 - 89.9 1 2 0 0.0037 8 0 0 0 3.68E+08 3.28E+08 - - - 2.0955 1 230117_WJC_METTL3_WT_vs_EV_F01.15235.15235.2 0.000758 20-Nov R.VFSGLVSTGLK.V sp|P13639|EF2_HUMAN 1 1106.6336 3.78 2914 15235 2 1106.635519 554.3241 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.72 3183 - 1.17E+06 - - - 1.7702 - 2.037 0.555 - 343.1 1 2 0 0.002 11 0 0 0 1.18E+08 3.13E+07 - - - 5.0643 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.15241.15241.2 0.000704 20-Oct R.IALTDNALIAR.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1169.6768 0.89 2918 15241 2 1169.677503 585.8457 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3183.7 - 767584 - - - 0.5822 - 2.007 0.361 - 223.6 1 2 0 0.0007 11 0 0 0 3.26E+07 3.66E+07 - - - 3.5917 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.15243.15243.2 0.0336 16-Oct R.LLGYVATLK[136.11].D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 984.6099 2.35 2920 15243 2 984.611213 493.3122 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 8.59 3183.9 - 5.22E+06 - - - 1.3152 - 1.861 0.356 - 210.8 1 2 0 0.0013 9 0 0 0 3.96E+08 1.68E+08 - - - 3.4669 0.9883 230117_WJC_METTL3_WT_vs_EV_F01.15253.15253.2 2.5 12-Jul K.NLILVVR.G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 825.5436 1.12 2927 15253 2 825.544309 413.7791 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3185 - 2.70E+06 - - - 0.831 - 1.382 0.046 - 179.5 1 2 0 0.0007 7 0 0 0 1.77E+08 1.58E+08 - - - 0.4057 1 230117_WJC_METTL3_WT_vs_EV_F01.15259.15259.2 1.20E-05 16-Oct K.YMAC[160.03]C[160.03]LLYR.G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1248.5454 3.07 2930 15259 2 1248.546691 625.28 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3185.8 - 248649 - - - 1.0692 - 1.927 0.58 - 441.8 1 2 0 0.0013 9 0 0 0 1.87E+08 6.07E+07 - - - 5.2222 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.15262.15262.2 0.00179 14-Aug K.AFAMIIDK.L "sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BND9|H3BND9_HUMAN" 8 907.4837 2.87 2932 15262 2 907.484263 454.7491 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 5.88 3186.1 - 4.40E+06 - - - 0.5928 - 1.584 0.45 - 254.2 1 2 0 0.0005 8 0 0 0 9.36E+07 3.26E+07 - - - 3.7517 0.985 230117_WJC_METTL3_WT_vs_EV_F01.15265.15265.2 2.62 12-Jun K.EILFYDR[166.11].L sp|Q08J23|NSUN2_HUMAN 1 964.4894 1.78 2935 15265 2 964.48987 483.252 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.37 3186.5 - 399198 - - - 0.5371 - 1.212 0.087 - 80.2 1 2 0 0.0005 7 0 0 0 9.69E+07 5.44E+07 - - - 0.2926 1 230117_WJC_METTL3_WT_vs_EV_F01.15270.15270.2 3.84E-05 16-Aug K.YMAC[160.03]C[160.03]LLYR[166.11].G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1258.5536 3.07 2938 15270 2 1258.556521 630.2841 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3187.1 - 279888 - - - 2.3003 - 1.69 0.558 - 175.6 1 2 0 0.0029 9 0 0 0 1.87E+08 6.07E+07 - - - 4.6795 0.9724 230117_WJC_METTL3_WT_vs_EV_F01.15276.15276.2 0.0588 22-Jul K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.19 2942 15276 2 1287.756816 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3187.9 - 166175 - - - -0.813 - 1.391 0.062 - 90.8 1 2 0 -0.001 12 0 0 0 2.13E+07 1.78E+07 - - - 0.3669 0.9765 230117_WJC_METTL3_WT_vs_EV_F01.15283.15283.2 0.316 22-May K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.19 2947 15283 2 1287.757197 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3188.8 - 0 - - - -0.5172 - 1.339 0.139 - 47.7 12 2 0 -0.0007 12 0 0 0 2.13E+07 1.78E+07 - - - 0.3535 0.981 230117_WJC_METTL3_WT_vs_EV_F01.15301.15301.2 6.07 12-Jul K.NLILVVR[166.11].G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 835.5519 1.12 2956 15301 2 835.551436 418.7832 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3190.9 - 9.08E+06 - - - -0.5469 - 1.249 0.104 - 282 1 2 0 -0.0005 7 0 0 0 1.76E+08 1.57E+08 - - - 0.5135 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.15309.15309.2 0.0534 12-Jul R.FLTVMMK[136.11].H "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 876.4693 1.25 2962 15309 2 876.469345 439.2419 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.75 3191.7 - 1.52E+06 - - - 0.089 - 1.397 0.353 - 159.7 1 2 0 0.0001 7 0 0 0 2.20E+08 1.76E+08 - - - 2.7076 0.9893 230117_WJC_METTL3_WT_vs_EV_F01.15311.15311.2 6.99 14-Jul K.LIINSLYK[136.11].N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 970.5943 0.93 2964 15311 2 970.596242 486.3044 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3191.8 - 3.51E+06 - - - 2.0338 - 1.143 0.144 - 77.4 1 2 0 0.002 8 0 0 0 1.51E+08 1.61E+08 - - - 0.5071 0.9944 230117_WJC_METTL3_WT_vs_EV_F01.15316.15316.2 0.0798 16-Sep R.LPEAAFLAR.T "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 986.5549 2.6 2967 15316 2 986.555113 494.2847 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 6 3192.4 - 3.55E+06 - - - 0.1997 - 1.436 0.138 - 222.2 1 2 0 0.0002 9 0 0 0 1.92E+08 7.38E+07 - - - 1.1071 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.15323.15323.2 0.0196 12-Jul R.FLTVMMK.H "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 868.4551 1.28 2972 15323 2 868.455046 435.2348 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.75 3193.2 - 3.26E+06 - - - -0.0242 - 1.315 0.286 - 147.7 1 2 0 0 7 0 0 0 2.18E+08 1.70E+08 - - - 2.0211 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.15329.15329.2 0.0517 14-Jul K.LIINSLYK.N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 962.5801 0.93 2976 15329 2 962.579848 482.2973 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3194 - 5.59E+06 - - - -0.2286 - 1.364 0.307 - 99.2 1 2 0 -0.0002 8 0 0 0 1.51E+08 1.63E+08 - - - 2.2447 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.15330.15330.2 0.0922 14-Aug K.GLVFLNGK.L sp|L0R8F8|MIDUO_HUMAN 1 846.4963 1.71 2977 15330 2 846.497004 424.2554 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 8.75 3194 - 2.18E+06 - - - 0.7856 - 1.486 0.234 - 204.7 1 2 0 0.0007 8 0 0 0 6.74E+07 3.95E+07 - - - 1.9637 0.9296 230117_WJC_METTL3_WT_vs_EV_F01.15331.15331.2 0.0464 16-Apr K.DDAGLPPPK.A sp|O43909|EXTL3_HUMAN 1 908.4603 2.51 2978 15331 2 908.465381 455.2374 Exostosin-like 3 OS=Homo sapiens OX=9606 GN=EXTL3 PE=1 SV=1 4.21 3194.2 - 922779 - - - 5.5412 - 1.123 0.235 - 43.6 9 2 0 0.005 9 0 0 0 2.79E+07 1.11E+07 - - - 0.6845 0.987 230117_WJC_METTL3_WT_vs_EV_F01.15336.15336.2 5.49 14-Aug K.NVPYVFVR[166.11].S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 1002.5526 1.58 2981 15336 2 1002.55258 502.2836 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3194.8 - 3.94E+06 - - - -0.0409 - 1.229 0.123 - 172.6 1 2 0 0 8 0 0 0 1.90E+08 1.21E+08 - - - 0.5714 0.9962 230117_WJC_METTL3_WT_vs_EV_F01.15337.15337.2 0.159 12-Jun K.EILFYDR.L sp|Q08J23|NSUN2_HUMAN 1 954.4811 1.78 2982 15337 2 954.481247 478.2478 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.37 3194.9 - 2.08E+07 - - - 0.1729 - 1.143 0.265 - 103.9 1 2 0 0.0002 7 0 0 0 9.69E+07 5.44E+07 - - - 1.4217 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.15339.15339.2 0.00675 16-Oct R.LLVHMGLLK.S sp|P46060|RAGP1_HUMAN 1 1022.6311 5.18 2984 15339 2 1022.635577 512.3228 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 8.76 3195.1 - 1.92E+06 - - - 4.419 - 1.917 0.367 - 221.3 1 2 0 0.0045 9 0 0 0 1.44E+07 2.78E+06 - - - 3.6329 0.9903 230117_WJC_METTL3_WT_vs_EV_F01.15351.15351.2 0.0944 12-Jul R.LYIWSGR[166.11].D "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 903.4842 2.87 2992 15351 2 903.482246 452.7494 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 8.75 3196.6 - 627440 - - - -2.1716 - 1.377 0.245 - 165.7 1 2 0 -0.002 7 0 0 0 9.80E+07 3.41E+07 - - - 1.8636 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.15367.15367.2 0.0047 18-Aug R.LVQAFQFTDK.H "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 3 1195.6237 3.61 3003 15367 2 1195.624059 598.8191 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.84 3198.6 - 372241 - - - 0.2802 - 1.566 0.301 - 117.2 1 2 0 0.0003 10 0 0 0 6.01E+06 1.66E+06 - - - 2.516 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.15377.15377.2 0.321 18-Sep K.IVLLSANSIR[166.11].A "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 1094.6687 2.06 3008 15377 2 1094.668654 548.3416 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 9.75 3200 - 1.03E+06 - - - -0.0548 - 1.775 0.317 - 183.1 1 2 0 -0.0001 10 0 0 0 3.94E+07 1.91E+07 - - - 2.984 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.15379.15379.2 0.219 18-Sep K.IVLLSANSIR.A "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 1084.6604 2.01 3010 15379 2 1084.661945 543.3375 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 9.75 3200.2 - 2.50E+06 - - - 1.3838 - 1.461 0.235 - 225.4 1 2 0 0.0015 10 0 0 0 3.95E+07 1.96E+07 - - - 1.8345 1 230117_WJC_METTL3_WT_vs_EV_F01.15390.15390.2 2.48E-06 14/22 K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 484.21 3016 15390 2 1356.68825 679.3515 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3201.5 - 578147 - - - -0.1909 - 2.929 0.384 - 921.3 1 2 0 -0.0003 12 0 0 0 2.12E+07 4.37E+04 - - - 4.7048 0.999 230117_WJC_METTL3_WT_vs_EV_F01.15391.15391.2 0.0198 22-Sep K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.16 3017 15391 2 1277.751819 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3201.7 - 651840 - - - 1.7421 - 1.521 0.305 - 161.2 1 2 0 0.0022 12 0 0 0 1.19E+07 1.03E+07 - - - 2.3965 0.9941 230117_WJC_METTL3_WT_vs_EV_F01.15396.15396.2 2.71 12-Aug R.IYLYLTK.V "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 912.5321 1.78 3020 15396 2 912.533073 457.2733 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.5 3202.3 - 1.33E+06 - - - 1.1156 - 1.46 0.083 - 195.9 1 2 0 0.001 7 0 0 0 7.45E+07 4.18E+07 - - - 0.8528 0.9905 230117_WJC_METTL3_WT_vs_EV_F01.15397.15397.2 3.27 12-Aug R.IYLYLTK[136.11].V "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 920.5463 1.78 3021 15397 2 920.547008 461.2804 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.5 3202.4 - 989063 - - - 0.818 - 1.42 0.054 - 188.3 1 2 0 0.0008 7 0 0 0 7.45E+07 4.18E+07 - - - 0.5507 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.15407.15407.2 2.85E-05 20-Nov R.AVAQALEVIPR.T "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1165.6819 999 3029 15407 2 1165.680946 583.8482 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.05 3203.6 - 129534 - - - -0.8253 - 2.083 0.379 - 284 1 2 0 -0.001 11 0 0 0 2.94E+06 0.00E+00 - - - 3.8251 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.15408.15408.2 0.0279 16-Jul R.YLYLSTMER.S "sp|Q10570|CPSF1_HUMAN,tr|A0A087X101|A0A087X101_HUMAN" 2 1174.5692 0.69 3030 15408 2 1174.574125 588.2919 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6 3203.7 - 128862 - - - 4.1539 - 1.329 0.364 - 162.8 1 2 0 0.0049 9 0 0 0 3.97E+06 5.76E+06 - - - 2.5508 0.9364 230117_WJC_METTL3_WT_vs_EV_F01.15412.15412.2 0.299 16-May K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 23.14 3032 15412 2 1014.540464 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3204.3 - 3.15E+06 - - - 5.8046 - 1.465 0.162 - 47.3 10 2 0 0.0059 9 0 0 0 2.30E+08 9.94E+06 - - - 0.8937 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.15416.15416.2 0.00566 16-Aug R.YLYLSTMER[166.11].S "sp|Q10570|CPSF1_HUMAN,tr|A0A087X101|A0A087X101_HUMAN" 2 1184.5775 0.69 3036 15416 2 1184.579974 593.296 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6 3204.7 - 243399 - - - 2.075 - 1.475 0.383 - 218.5 1 2 0 0.0025 9 0 0 0 3.97E+06 5.76E+06 - - - 2.9935 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.15424.15424.2 0.00158 14-Aug R.FADFTVYR[166.11].N "sp|Q9NY61|AATF_HUMAN,tr|A0A7P0T868|A0A7P0T868_HUMAN,tr|A0A7P0TAR0|A0A7P0TAR0_HUMAN,tr|A0A7P0TBI0|A0A7P0TBI0_HUMAN,tr|A0A7P0Z4P2|A0A7P0Z4P2_HUMAN,tr|A0A7P0Z4N2|A0A7P0Z4N2_HUMAN,tr|A0A087WTH8|A0A087WTH8_HUMAN,tr|A0A7P0Z434|A0A7P0Z434_HUMAN" 8 1027.5003 1.02 3042 15424 2 1027.50332 514.7574 Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1 5.84 3205.6 - 1.11E+06 - - - 2.9859 - 1.677 0.319 - 191.8 1 2 0 0.0031 8 0 0 0 2.28E+07 2.23E+07 - - - 2.9554 0.987 230117_WJC_METTL3_WT_vs_EV_F01.15426.15426.2 0.249 14-Jun R.LLLNYAVR.L "sp|Q92989|CLP1_HUMAN,tr|E9PL17|E9PL17_HUMAN,tr|E9PKV5|E9PKV5_HUMAN" 3 960.5757 2.57 3044 15426 2 960.579225 481.2951 Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1 8.75 3205.8 - 385865 - - - 3.7196 - 1.277 0.173 - 97.1 1 2 0 0.0036 8 0 0 0 1.71E+07 6.65E+06 - - - 1.0551 0.9935 230117_WJC_METTL3_WT_vs_EV_F01.15431.15431.2 0.577 12-Jun K.FLLLQQK[136.11].Y "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 896.5575 2.06 3047 15431 2 896.558907 449.286 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 8.75 3206.4 - 876590 - - - 1.5816 - 1.221 0.151 - 95.6 1 2 0 0.0014 7 0 0 0 6.51E+07 3.15E+07 - - - 0.7885 0.9912 230117_WJC_METTL3_WT_vs_EV_F01.15436.15436.2 0.359 16-Aug R.ALVQSLLAK.E sp|Q9NX46|ADPRS_HUMAN 1 941.591 3.03 3051 15436 2 941.593017 471.8028 ADP-ribose glycohydrolase ARH3 OS=Homo sapiens OX=9606 GN=ADPRS PE=1 SV=1 8.8 3207.1 - 173587 - - - 2.1772 - 1.34 0.108 - 102 1 2 0 0.0021 9 0 0 0 1.29E+07 4.24E+06 - - - 0.6848 0.9783 230117_WJC_METTL3_WT_vs_EV_F01.15439.15439.2 0.0129 13/16 R.PAVLSGYFK.Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 980.5331 1.06 3052 15439 2 980.534977 491.2738 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.01 3207.5 - 3.06E+06 - - - 1.8959 - 2.189 0.433 - 609.5 1 1 0 0.0019 9 0 0 0 1.56E+08 1.47E+08 - - - 4.5051 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.15441.15441.2 0.0769 12-Jul K.SEFVILR.D "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 862.4913 0.97 3054 15441 2 862.492502 432.2529 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 5.72 3207.6 - 1.18E+06 - - - 1.4481 - 1.423 0.118 - 178.2 1 2 0 0.0012 7 0 0 0 6.20E+07 6.41E+07 - - - 1.0299 1 230117_WJC_METTL3_WT_vs_EV_F01.15443.15443.2 7.89E-06 18-Oct R.LITLEEEMTK.Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1205.6213 4.96 3056 15443 2 1205.624073 603.8179 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3207.9 - 400742 - - - 2.2661 - 2.048 0.501 - 274.4 1 2 0 0.0027 10 0 0 0 2.84E+07 5.72E+06 - - - 4.7415 0.8593 230117_WJC_METTL3_WT_vs_EV_F01.15449.15449.2 15.9 14-May R.LFIGGIPK.M "sp|A0AV96|RBM47_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6REZ6|D6REZ6_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 5 843.5218 1.37 3060 15449 2 843.525673 422.7682 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 8.75 3208.6 - 1.37E+06 - - - 4.5618 - 1.212 0.043 - 73.7 3 2 0 0.0038 8 0 0 0 6.15E+07 4.49E+07 - - - -0.2759 0.998 230117_WJC_METTL3_WT_vs_EV_F01.15452.15452.2 0.0591 14-Jul R.NIVLYDMR.Q "sp|Q9NV06|DCA13_HUMAN,tr|A0A087WT20|A0A087WT20_HUMAN,tr|A0A087X1F8|A0A087X1F8_HUMAN" 3 1022.5219 999 3063 15452 2 1022.525436 512.2682 DDB1- and CUL4-associated factor 13 OS=Homo sapiens OX=9606 GN=DCAF13 PE=1 SV=2 5.84 3208.9 - 750199 - - - 3.4571 - 1.308 0.371 - 141 1 2 0 0.0035 8 0 0 0 9.01E+06 0.00E+00 - - - 2.5899 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.15459.15459.2 0.000142 20-Oct R.LVEMASSLAIR.E "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1188.6536 3.98 3068 15459 2 1188.657183 595.3341 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3209.8 - 268060 - - - 2.9773 - 2.195 0.46 - 298.8 1 2 0 0.0035 11 0 0 0 5.48E+06 1.38E+06 - - - 4.5643 0.9948 230117_WJC_METTL3_WT_vs_EV_F01.15461.15461.2 0.358 12-Jul R.WGGLDLR.R sp|Q9H7N4|SFR19_HUMAN 1 815.429 0.87 3070 15461 2 815.430456 408.7218 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.84 3209.9 - 1.14E+06 - - - 1.8015 - 1.302 0.15 - 229.8 1 2 0 0.0015 7 0 0 0 5.81E+07 6.67E+07 - - - 0.9846 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.15463.15463.2 0.065 18-Jul K.SYLYPSTLVR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1197.6394 0.37 3072 15463 2 1197.640501 599.827 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 3210.1 - 325361 - - - 0.941 - 1.644 0.26 - 212.8 1 2 0 0.0011 10 0 0 0 5.15E+08 1.39E+09 - - - 2.3487 0.9751 230117_WJC_METTL3_WT_vs_EV_F01.15467.15467.2 1.43 12-Jun R.LIMQYLK[136.11].E sp|Q2TAY7|SMU1_HUMAN 1 915.5343 0.92 3074 15467 2 915.536983 458.7744 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.59 3210.7 - 4.58E+06 - - - 2.9185 - 1.06 0.135 - 94.4 1 2 0 0.0027 7 0 0 0 5.61E+07 6.10E+07 - - - 0.2219 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.15471.15471.2 0.00604 18-Oct R.LITLEEEMTK[136.11].Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1213.6355 5.79 3078 15471 2 1213.634501 607.825 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3211.1 - 695330 - - - -0.8569 - 1.838 0.435 - 258.8 1 2 0 -0.001 10 0 0 0 2.67E+07 4.61E+06 - - - 3.9526 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.15472.15472.2 0.0305 12-Jun R.WFVTC[160.03]VR.Q "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN,tr|A0A140T954|A0A140T954_HUMAN" 3 966.4746 0.84 3079 15472 2 966.476837 484.2446 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 8.25 3211.2 - 577226 - - - 2.3581 - 1.113 0.301 - 81 1 2 0 0.0023 7 0 0 0 9.80E+06 1.17E+07 - - - 1.6027 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.15474.15474.2 6.29E-06 22-Nov R.EHALLAYTLGVK.Q "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 11 1313.7343 3.51 3081 15474 2 1313.734526 657.8744 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.85 3211.4 - 238502 - - - 0.1439 - 2.05 0.383 - 186.7 1 2 0 0.0002 12 0 0 0 4.70E+06 1.34E+06 - - - 3.7585 0.9689 230117_WJC_METTL3_WT_vs_EV_F01.15475.15475.2 0.103 16-Jun R.LLDEYNLVR.S "sp|P46531|NOTC1_HUMAN,tr|A0A7P0T8U6|A0A7P0T8U6_HUMAN,tr|A0A7P0TA56|A0A7P0TA56_HUMAN,tr|A0A7P0TB20|A0A7P0TB20_HUMAN,tr|A0A7P0T8W1|A0A7P0T8W1_HUMAN" 5 1133.6081 2.43 3082 15475 2 1133.616205 567.8113 Neurogenic locus notch homolog protein 1 OS=Homo sapiens OX=9606 GN=NOTCH1 PE=1 SV=4 4.37 3211.6 - 151593 - - - 7.1727 - 1.427 0.299 - 74.3 1 2 0 0.0081 9 0 0 0 6.23E+06 2.56E+06 - - - 2.2756 0.8597 230117_WJC_METTL3_WT_vs_EV_F01.15479.15479.2 0.0293 16-Aug R.AVFPSIVGR[166.11].P "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 31 954.5526 1.26 3085 15479 2 954.555652 478.2836 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 9.79 3211.9 - 2.68E+06 - - - 3.1753 - 1.638 0.259 - 229.5 1 1 0 0.003 9 0 0 0 1.57E+09 1.25E+09 - - - 2.3807 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.15481.15481.2 0.0105 18-Jun K.VLFTGVVDAR[166.11].G sp|Q14676|MDC1_HUMAN 1 1085.6109 2.59 3087 15481 2 1085.613155 543.8127 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 5.81 3212.1 - 680929 - - - 2.1094 - 1.477 0.242 - 85.7 1 2 0 0.0023 10 0 0 0 4.59E+07 1.77E+07 - - - 1.9163 0.9913 230117_WJC_METTL3_WT_vs_EV_F01.15488.15488.2 0.146 14-Aug K.LGFESIYK[136.11].L "sp|P49643|PRI2_HUMAN,tr|A0A5F9ZHU7|A0A5F9ZHU7_HUMAN" 2 963.5157 4.38 3092 15488 2 963.519375 482.7651 DNA primase large subunit OS=Homo sapiens OX=9606 GN=PRIM2 PE=1 SV=2 6 3212.9 - 383763 - - - 3.8308 - 1.344 0.204 - 112.6 1 2 0 0.0037 8 0 0 0 4.59E+07 1.05E+07 - - - 1.4383 1 230117_WJC_METTL3_WT_vs_EV_F01.15492.15492.2 4.88E-05 16-Oct K.LGEWVGLC[160.03]K[136.11].L sp|P25398|RS12_HUMAN 1 1068.5518 2.29 3094 15492 2 1068.553669 535.2832 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3213.4 - 6.37E+06 - - - 1.794 - 2.068 0.476 - 334.1 1 2 0 0.0019 9 0 0 0 3.95E+08 1.73E+08 - - - 4.6582 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.15493.15493.2 0.0112 14-Jul K.NVPYVFVR.S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 992.5444 0.95 3095 15493 2 992.548006 497.2795 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3213.5 - 4.95E+06 - - - 3.6825 - 1.288 0.314 - 187.7 1 2 0 0.0037 8 0 0 0 4.84E+08 5.08E+08 - - - 2.1224 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.15506.15506.2 8.47E-05 14-Aug R.GFTLVGMK[136.11].M "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 859.4717 0.96 3104 15506 2 859.473344 430.7431 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.75 3215.1 - 5.37E+06 - - - 1.9012 - 1.77 0.41 - 262.6 1 2 0 0.0016 8 0 0 0 1.28E+09 1.34E+09 - - - 3.7908 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.15508.15508.2 0.000209 22-Oct K.AVASAAAALVLK.A sp|Q9Y490|TLN1_HUMAN 1 1083.6652 1.25 3106 15508 2 1083.667458 542.8399 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.8 3215.4 - 1.06E+06 - - - 2.0883 - 2.178 0.347 - 207.9 1 2 0 0.0023 12 0 0 0 3.86E+07 3.08E+07 - - - 3.6514 0.988 230117_WJC_METTL3_WT_vs_EV_F01.15516.15516.3 0.249 Nov-56 K.LVEALC[160.03]AEHQINLIK.V sp|P25398|RS12_HUMAN 1 1749.9447 2.65 3111 15516 3 1749.948673 584.3222 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.4 3216.3 - 657522 - - - 2.2469 - 1.407 0.183 - 76.2 1 2 0 0.0039 15 0 0 0 6.98E+06 2.64E+06 - - - 1.4702 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.15520.15520.2 0.212 12-Aug K.TSILVFK[136.11].D sp|Q9BRS2|RIOK1_HUMAN 1 814.5044 0.67 3113 15520 2 814.507431 408.2595 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 8.41 3216.9 - 4.79E+06 - - - 3.7323 - 1.886 0.326 - 276.5 1 2 0 0.003 7 0 0 0 4.99E+07 7.45E+07 - - - 3.4582 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.15525.15525.2 0.0875 18-Jul K.VLFTGVVDAR.G sp|Q14676|MDC1_HUMAN 1 1075.6026 2.6 3117 15525 2 1075.603468 538.8086 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 5.81 3217.4 - 835167 - - - 0.8116 - 1.383 0.26 - 163.3 1 2 0 0.0009 10 0 0 0 4.98E+07 1.92E+07 - - - 1.8662 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.15534.15534.2 0.0445 12-Aug K.LC[160.03]TFILK[136.11].N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 901.5187 1.21 3120 15534 2 901.519732 451.7666 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3218.6 - 1.39E+06 - - - 1.188 - 1.331 0.185 - 142.2 1 2 0 0.0011 7 0 0 0 4.94E+07 4.09E+07 - - - 1.3131 1 230117_WJC_METTL3_WT_vs_EV_F01.15537.15537.2 4.03E-05 16-Dec K.LGEWVGLC[160.03]K.L sp|P25398|RS12_HUMAN 1 1060.5376 2.29 3122 15537 2 1060.538863 531.2761 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3218.9 - 9.44E+06 - - - 1.2362 - 2.241 0.516 - 576.6 1 2 0 0.0013 9 0 0 0 3.95E+08 1.73E+08 - - - 5.1862 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.15538.15538.2 0.0329 12-Aug K.LC[160.03]TFILK.N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 893.5045 1.21 3123 15538 2 893.506152 447.7595 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3219 - 936264 - - - 1.8925 - 1.352 0.181 - 157.7 1 2 0 0.0017 7 0 0 0 5.54E+07 4.58E+07 - - - 1.3329 0.9893 230117_WJC_METTL3_WT_vs_EV_F01.15539.15539.2 0.0342 22-Jul K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.2 3124 15539 2 1287.759111 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3219.1 - 534378 - - - 0.9691 - 1.586 0.044 - 80.6 2 2 0 0.0012 12 0 0 0 9.69E+07 8.05E+07 - - - 0.4447 0.8793 230117_WJC_METTL3_WT_vs_EV_F01.15547.15547.2 0.101 18-Aug K.LLHHLSDLAL.T "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1130.6448 - 3130 15547 2 1130.647599 566.3297 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3219.9 - 1.42E+06 - - - 2.4809 - 1.608 0.241 - 137.2 1 1 0 0.0028 10 0 0 0 - - - - - 2.146 0.963 230117_WJC_METTL3_WT_vs_EV_F01.15548.15548.2 17.5 14-Aug K.AGLSVLLK.A "sp|Q969N2|PIGT_HUMAN,tr|A0A1W2PRZ8|A0A1W2PRZ8_HUMAN,tr|H7C2Y2|H7C2Y2_HUMAN,tr|A0A1W2PPR6|A0A1W2PPR6_HUMAN,tr|A0A1W2PPS0|A0A1W2PPS0_HUMAN,tr|A0A1W2PR92|A0A1W2PR92_HUMAN,tr|A0A1W2PPI8|A0A1W2PPI8_HUMAN,tr|A0A1W2PRG1|A0A1W2PRG1_HUMAN,tr|A0A1W2PRV7|A0A1W2PRV7_HUMAN,tr|A0A1W2PQ52|A0A1W2PQ52_HUMAN,tr|A0A1W2PRH2|A0A1W2PRH2_HUMAN,tr|A0A1W2PNP0|A0A1W2PNP0_HUMAN,tr|A0A1W2PNW9|A0A1W2PNW9_HUMAN,tr|A0A1W2PP57|A0A1W2PP57_HUMAN,tr|A0A1W2PPQ7|A0A1W2PPQ7_HUMAN,tr|A0A1W2PQ29|A0A1W2PQ29_HUMAN,tr|A0A1W2PQN1|A0A1W2PQN1_HUMAN,tr|A0A1W2PPC3|A0A1W2PPC3_HUMAN" 18 799.5167 1.25 3131 15548 2 799.518208 400.7656 GPI transamidase component PIG-T OS=Homo sapiens OX=9606 GN=PIGT PE=1 SV=1 8.8 3220 - 1.21E+06 - - - 1.8361 - 1.158 0.039 - 111.9 2 2 0 0.0015 8 0 0 0 3.75E+07 3.00E+07 - - - -0.3635 0.9932 230117_WJC_METTL3_WT_vs_EV_F01.15560.15560.2 0.588 12-Jun R.FLVTVIK.D "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 818.5266 1.88 3136 15560 2 818.528407 410.2706 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3221.4 - 1.42E+06 - - - 2.2369 - 1.31 0.134 - 124.4 1 2 0 0.0018 7 0 0 0 1.60E+08 8.48E+07 - - - 0.8857 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.15580.15580.2 0.067 16-Aug R.LIVNVNDLR[166.11].R sp|P25205|MCM3_HUMAN 1 1064.6218 6.93 3146 15580 2 1064.621878 533.3182 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.84 3224 - 1.38E+06 - - - 0.1071 - 1.402 0.3 - 179.3 1 2 0 0.0001 9 0 0 0 2.41E+08 3.48E+07 - - - 2.2343 0.9823 230117_WJC_METTL3_WT_vs_EV_F01.15590.15590.2 10.9 12-Jun R.LILEALK[136.11].Q "sp|Q8IX18|DHX40_HUMAN,sp|Q6TDP4|KLH17_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|D6RJB0|D6RJB0_HUMAN,tr|H0Y9K3|H0Y9K3_HUMAN,tr|A0A3B3ISF8|A0A3B3ISF8_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN,tr|Q0VGE6|Q0VGE6_HUMAN,tr|J3QLT4|J3QLT4_HUMAN,tr|A0A3B3IT29|A0A3B3IT29_HUMAN,tr|D6R9W6|D6R9W6_HUMAN,tr|G3V0E9|G3V0E9_HUMAN" 12 806.5357 1.29 3150 15590 2 806.535329 404.2751 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 6 3225.3 - 4.26E+06 - - - -0.4488 - 1.198 0.123 - 86.2 1 2 0 -0.0004 7 0 0 0 5.16E+07 4.02E+07 - - - 0.5218 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.15591.15591.2 5.79E-05 22-Sep R.LVPAAEEEELLR[166.11].E sp|Q9Y4B5|MTCL1_HUMAN 1 1377.7379 1.02 3151 15591 2 1377.74054 689.8762 Microtubule cross-linking factor 1 OS=Homo sapiens OX=9606 GN=MTCL1 PE=1 SV=5 4.09 3225.4 - 146958 - - - 1.9046 - 1.908 0.463 - 277.6 1 2 0 0.0026 12 0 0 0 2.45E+06 2.40E+06 - - - 4.1598 0.8541 230117_WJC_METTL3_WT_vs_EV_F01.15600.15600.2 0.426 12-Jul R.C[160.03]ILPFDK[136.11].E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 899.4666 1.27 3155 15600 2 899.462696 450.7406 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.83 3226.5 - 967425 - - - -4.3681 - 1.367 0.088 - 220.4 1 2 0 -0.0039 7 0 0 0 1.63E+08 1.29E+08 - - - 0.6803 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.15608.15608.2 0.00135 16-Aug R.AATLMMLGR.F "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PR93|A0A6I8PR93_HUMAN,tr|K7ESP1|K7ESP1_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|K7EJE9|K7EJE9_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|K7ELJ8|K7ELJ8_HUMAN,tr|K7EN19|K7EN19_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EJL5|K7EJL5_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|K7EJV7|K7EJV7_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 21 962.5041 0.96 3159 15608 2 962.502971 482.2593 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 9.79 3227.5 - 2.43E+06 - - - -1.2177 - 1.552 0.304 - 209.3 1 2 0 -0.0012 9 0 0 0 6.03E+07 6.28E+07 - - - 2.5576 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.15611.15611.2 0.466 12-Aug R.ALTALFK.E "sp|Q9UBB4|ATX10_HUMAN,tr|A0A1W2PQD2|A0A1W2PQD2_HUMAN" 2 762.464 1.68 3160 15611 2 762.464823 382.2393 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 8.8 3227.9 - 2.78E+06 - - - 1.1109 - 1.478 0.168 - 266.7 1 2 0 0.0008 7 0 0 0 6.00E+07 3.56E+07 - - - 1.5195 0.992 230117_WJC_METTL3_WT_vs_EV_F01.15612.15612.2 0.231 12-Aug R.C[160.03]ILPFDK.E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 891.4524 1.18 3161 15612 2 891.452913 446.7335 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.83 3228 - 2.65E+06 - - - 0.5474 - 1.297 0.117 - 310 1 2 0 0.0005 7 0 0 0 1.52E+08 1.29E+08 - - - 0.729 0.9903 230117_WJC_METTL3_WT_vs_EV_F01.15613.15613.2 0.117 12-Jul K.DFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 834.46 1.7 3162 15613 2 834.464004 418.2373 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.84 3228 - 4.99E+07 - - - 4.8546 - 1.396 0.251 - 169.7 1 2 0 0.0041 7 0 0 0 1.55E+09 9.12E+08 - - - 1.9507 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.15614.15614.2 0.9 14-Aug R.GLVVPVIR[166.11].N sp|P36957|ODO2_HUMAN 1 861.5675 0.87 3163 15614 2 861.56813 431.791 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3228 - 8.94E+06 - - - 0.6813 - 1.602 0.188 - 366.8 1 2 0 0.0006 8 0 0 0 1.12E+08 1.29E+08 - - - 1.8507 0.9868 230117_WJC_METTL3_WT_vs_EV_F01.15620.15620.2 3.25 12-Jul R.LWISVAR[166.11].Y sp|Q15029|U5S1_HUMAN 1 853.5049 1.61 3167 15620 2 853.504506 427.7597 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 9.75 3228.8 - 4.11E+06 - - - -0.512 - 1.331 0.11 - 231 1 2 0 -0.0004 7 0 0 0 2.07E+08 1.29E+08 - - - 0.7593 0.998 230117_WJC_METTL3_WT_vs_EV_F01.15621.15621.2 0.0385 12-Jul K.YIQELWR.K "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1006.5236 0.78 3168 15621 2 1006.523337 504.2691 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 6 3228.9 - 1.53E+06 - - - -0.2772 - 1.367 0.299 - 182.8 1 2 0 -0.0003 7 0 0 0 1.19E+08 1.52E+08 - - - 2.2399 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.15622.15622.2 0.0547 12-Jul K.YIQELWR[166.11].K "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1016.5319 0.78 3169 15622 2 1016.534137 509.2732 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 6 3228.9 - 2.35E+06 - - - 2.2144 - 1.509 0.348 - 203.6 1 2 0 0.0023 7 0 0 0 1.19E+08 1.52E+08 - - - 2.9143 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.15625.15625.2 0.00293 14-Aug R.LYNYFYDR.R "sp|Q96GD4|AURKB_HUMAN,tr|J3QR41|J3QR41_HUMAN,tr|J3QLN8|J3QLN8_HUMAN,tr|J3KTD6|J3KTD6_HUMAN,tr|J3KT86|J3KT86_HUMAN" 5 1152.524 2.12 3172 15625 2 1152.527227 577.2693 Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3 5.83 3229.2 - 410330 - - - 2.7913 - 1.47 0.409 - 215.4 1 2 0 0.0032 8 0 0 0 9.23E+06 4.35E+06 - - - 3.2228 0.9917 230117_WJC_METTL3_WT_vs_EV_F01.15629.15629.2 0.85 16-Jun K.FVPLLPGNR.S sp|P78527|PRKDC_HUMAN 1 1011.5866 1.02 3174 15629 2 1011.58821 506.8006 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3229.7 - 588331 - - - 1.64 - 1.221 0.135 - 121.2 1 2 0 0.0017 9 0 0 0 5.16E+07 5.05E+07 - - - 0.6152 0.9666 230117_WJC_METTL3_WT_vs_EV_F01.15632.15632.2 0.0961 14-Jun K.VFPLAEYR.T sp|Q86T24|KAISO_HUMAN 1 993.5284 5.63 3177 15632 2 993.525752 497.7715 Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2 5.97 3230.1 - 639269 - - - -2.632 - 1.265 0.177 - 139.3 1 2 0 -0.0026 8 0 0 0 2.25E+07 3.99E+06 - - - 1.0565 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.15636.15636.2 0.0555 16-Aug K.LLPDTILEK[136.11].L "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1048.626 0.74 3179 15636 2 1048.627908 525.3203 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 4.37 3230.6 - 577581 - - - 1.8558 - 1.357 0.22 - 134.9 1 2 0 0.0019 9 0 0 0 9.87E+07 1.34E+08 - - - 1.5485 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.15637.15637.2 0.0185 16-Jul K.FVPLLPGNR[166.11].S sp|P78527|PRKDC_HUMAN 1 1021.5948 1.01 3180 15637 2 1021.59551 511.8047 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3230.7 - 1.28E+06 - - - 0.6744 - 1.429 0.144 - 173.7 1 2 0 0.0007 9 0 0 0 5.12E+07 5.05E+07 - - - 1.1371 0.9962 230117_WJC_METTL3_WT_vs_EV_F01.15640.15640.2 0.188 14-Aug R.LLFGPTVR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 911.5468 0.95 3181 15640 2 911.547446 456.7807 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3231.1 - 3.11E+06 - - - 0.6999 - 1.344 0.18 - 182.7 1 2 0 0.0006 8 0 0 0 6.42E+07 6.78E+07 - - - 1.2619 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.15643.15643.2 0.0453 14-Jun K.FLILNPSK.R "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 930.5539 0.39 3184 15643 2 930.554723 466.2842 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 8.75 3231.5 - 956583 - - - 0.9339 - 1.263 0.297 - 89.8 1 2 0 0.0009 8 0 0 0 1.81E+07 4.62E+07 - - - 1.9386 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.15644.15644.2 0.0124 16-Oct K.LITWSPVC[160.03]R.N "sp|P07203|GPX1_HUMAN,tr|A0A2R8Y6B6|A0A2R8Y6B6_HUMAN" 2 1130.5907 2.73 3185 15644 2 1130.59605 566.3026 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 8.25 3231.6 - 729629 - - - 4.7763 - 2.139 0.328 - 320.4 1 2 0 0.0054 9 0 0 0 1.73E+07 6.34E+06 - - - 3.6616 1 230117_WJC_METTL3_WT_vs_EV_F01.15646.15646.2 0.000147 22-Oct R.LLETC[160.03]SIALVGK.Y "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN,tr|A0A3B3ISY3|A0A3B3ISY3_HUMAN" 7 1302.7217 3.07 3187 15646 2 1302.727278 652.3681 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 5.99 3231.9 - 172314 - - - 4.2634 - 2.144 0.541 - 283.8 1 2 0 0.0056 12 0 0 0 3.29E+06 1.07E+06 - - - 5.0418 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.15648.15648.2 0.388 12-Jul K.DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 844.4682 1.7 3188 15648 2 844.469026 423.2414 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.84 3232.1 - 2.53E+07 - - - 0.9509 - 1.297 0.185 - 244.5 1 2 0 0.0008 7 0 0 0 1.55E+09 9.12E+08 - - - 1.2312 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.15649.15649.2 0.0273 22-Oct K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.2 3189 15649 2 1277.751374 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3232.2 - 949043 - - - 1.3939 - 1.597 0.233 - 163.7 1 2 0 0.0018 12 0 0 0 9.39E+07 7.82E+07 - - - 1.9931 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.15650.15650.2 0.00179 16-Sep K.LLPDTILEK.L "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1040.6118 0.74 3190 15650 2 1040.611742 521.3132 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 4.37 3232.3 - 893852 - - - -0.0192 - 1.69 0.38 - 213 1 2 0 0 9 0 0 0 9.87E+07 1.33E+08 - - - 3.3657 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.15657.15657.2 1.50E-05 14-Sep K.YYVLNALK[136.11].H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 990.563 2.28 3195 15657 2 990.56459 496.2888 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.5 3233.2 - 2.44E+06 - - - 1.6375 - 1.522 0.415 - 193 1 2 0 0.0016 8 0 0 0 1.18E+08 5.19E+07 - - - 3.3725 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.15658.15658.2 0.0431 16-Sep R.LQDLLLGPK.A sp|Q8N201|INT1_HUMAN 1 995.6015 1.65 3196 15658 2 995.604004 498.808 Integrator complex subunit 1 OS=Homo sapiens OX=9606 GN=INTS1 PE=1 SV=2 5.84 3233.3 - 925413 - - - 2.4829 - 1.343 0.297 - 161.7 1 2 0 0.0025 9 0 0 0 8.92E+06 5.41E+06 - - - 2.087 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.15668.15668.2 0.0786 16-Jul R.VLGMTLIQK.C sp|Q04760|LGUL_HUMAN 1 1001.5943 1.32 3204 15668 2 1001.596959 501.8044 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3234.5 - 361618 - - - 2.6168 - 1.486 0.207 - 96.3 1 2 0 0.0026 9 0 0 0 3.28E+07 2.49E+07 - - - 1.715 0.956 230117_WJC_METTL3_WT_vs_EV_F01.15676.15676.2 1.22 14-Apr R.LLFGPTVR.L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 901.5385 0.63 3210 15676 2 901.540565 451.7765 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3235.4 - 3.26E+06 - - - 2.2484 - 0.836 0.187 - 39.9 4 2 0 0.002 8 0 0 0 6.51E+07 1.04E+08 - - - -0.3876 0.9945 230117_WJC_METTL3_WT_vs_EV_F01.15678.15678.2 0.178 12-Jun M.GVPAFFR.W sp|Q9H0D6|XRN2_HUMAN 1 792.4283 0.88 3212 15678 2 792.430226 397.2214 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 3235.6 - 565566 - - - 2.4822 - 1.111 0.239 - 142.7 1 2 0 0.002 7 0 0 0 2.31E+08 2.64E+08 - - - 1.1392 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.15682.15682.2 0.185 14-Aug R.LGDLVWGK.L "sp|Q49A26|GLYR1_HUMAN,sp|Q9UBC3|DNM3B_HUMAN,tr|K7EQB2|K7EQB2_HUMAN,tr|K7ELL0|K7ELL0_HUMAN" 4 886.4913 0.82 3215 15682 2 886.494085 444.2529 Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4 5.84 3236 - 3.11E+06 - - - 3.1946 - 1.478 0.165 - 160.3 1 2 0 0.0028 8 0 0 0 5.95E+07 7.22E+07 - - - 1.4371 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.15685.15685.2 0.00947 18-Jul R.LVPC[160.03]ILEAAK.Q "sp|Q96ER3|SAAL1_HUMAN,tr|H0YCN7|H0YCN7_HUMAN,tr|H0YEK5|H0YEK5_HUMAN,tr|J3KND1|J3KND1_HUMAN,tr|E9PMD2|E9PMD2_HUMAN,tr|E9PRZ1|E9PRZ1_HUMAN" 6 1112.6264 1.29 3217 15685 2 1112.629951 557.3205 Protein SAAL1 OS=Homo sapiens OX=9606 GN=SAAL1 PE=1 SV=2 5.99 3236.3 - 287494 - - - 3.2212 - 1.376 0.304 - 119.5 1 2 0 0.0036 10 0 0 0 7.46E+06 5.76E+06 - - - 2.1761 0.8458 230117_WJC_METTL3_WT_vs_EV_F01.15687.15687.2 4.72 14-May K.LAVSSLLR.V "sp|Q7Z3U7|MON2_HUMAN,tr|A0A286YFF8|A0A286YFF8_HUMAN" 2 857.5335 1.64 3219 15687 2 857.536255 429.774 Protein MON2 homolog OS=Homo sapiens OX=9606 GN=MON2 PE=1 SV=3 9.75 3236.6 - 386907 - - - 3.2687 - 1.207 0.018 - 51 25 2 0 0.0028 8 0 0 0 1.00E+07 6.10E+06 - - - -0.884 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.15690.15690.2 0.0308 18-Oct K.LIESAEELIR.D "sp|Q13217|DNJC3_HUMAN,tr|X6R9L0|X6R9L0_HUMAN" 2 1171.6449 1.64 3220 15690 2 1171.647299 586.8297 DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1 4.25 3236.9 - 164041 - - - 2.0877 - 2.022 0.273 - 296 1 2 0 0.0024 10 0 0 0 1.18E+07 7.22E+06 - - - 3.0219 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.15691.15691.2 0.256 18-Oct K.LIESAEELIR[166.11].D "sp|Q13217|DNJC3_HUMAN,tr|X6R9L0|X6R9L0_HUMAN" 2 1181.6531 1.64 3221 15691 2 1181.658212 591.8338 DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1 4.25 3237.1 - 144191 - - - 4.3067 - 2.188 0.358 - 262.2 1 2 0 0.0051 10 0 0 0 1.18E+07 7.22E+06 - - - 3.8691 0.9902 230117_WJC_METTL3_WT_vs_EV_F01.15697.15697.2 0.161 14-Jul K.YYVLNALK.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 982.5488 2.17 3226 15697 2 982.550886 492.2817 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.5 3237.8 - 8.32E+06 - - - 2.1556 - 1.058 0.188 - 108.7 1 2 0 0.0021 8 0 0 0 1.21E+08 5.56E+07 - - - 0.5989 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.15699.15699.2 0.0798 16-Sep R.VLGMTLIQK[136.11].C sp|Q04760|LGUL_HUMAN 1 1009.6085 1.35 3227 15699 2 1009.611961 505.8115 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3238 - 1.62E+06 - - - 3.3904 - 1.562 0.233 - 208.7 1 2 0 0.0034 9 0 0 0 3.34E+07 2.48E+07 - - - 2.0511 0.9622 230117_WJC_METTL3_WT_vs_EV_F01.15702.15702.2 1.85 16-May K.LISEEDLLR.K "sp|P01106|MYC_HUMAN,tr|A0A087WUS5|A0A087WUS5_HUMAN,tr|A0A494C1T8|A0A494C1T8_HUMAN,tr|H0YBT0|H0YBT0_HUMAN" 4 1086.5921 2.34 3230 15702 2 1086.595028 544.3033 Myc proto-oncogene protein OS=Homo sapiens OX=9606 GN=MYC PE=1 SV=1 4.14 3238.3 - 360772 - - - 2.7039 - 1.256 0.058 - 60.2 4 2 0 0.0029 9 0 0 0 4.83E+06 2.06E+06 - - - -0.1411 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.15706.15706.2 0.012 16-Jul R.FLPSPVVIK[136.11].K "sp|Q13618|CUL3_HUMAN,tr|H7C399|H7C399_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 3 1006.6307 0.62 3232 15706 2 1006.633126 504.3226 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 8.75 3238.8 - 1.86E+06 - - - 2.4557 - 1.24 0.321 - 134.8 1 2 0 0.0025 9 0 0 0 4.52E+07 7.31E+07 - - - 2.0335 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.15707.15707.2 0.000352 16-Sep K.YMTDGMLLR.E "sp|Q14562|DHX8_HUMAN,sp|O60231|DHX16_HUMAN,sp|O43143|DHX15_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|F5H658|F5H658_HUMAN" 5 1098.5202 1.24 3233 15707 2 1098.52379 550.2674 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 5.84 3238.9 - 980811 - - - 3.2799 - 1.468 0.445 - 251.1 1 2 0 0.0036 9 0 0 0 2.81E+07 2.26E+07 - - - 3.4373 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.15709.15709.2 0.00693 16-Aug R.LFEGNALLR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1031.5764 0.87 3235 15709 2 1031.580662 516.7955 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3238.9 - 5.08E+06 - - - 4.1509 - 1.71 0.391 - 218.2 1 2 0 0.0043 9 0 0 0 1.44E+09 1.65E+09 - - - 3.4797 0.9833 230117_WJC_METTL3_WT_vs_EV_F01.15714.15714.2 1.3 14-Jul K.MLLSLPEK[136.11].V "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 937.5398 1.11 3240 15714 2 937.544234 469.7772 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 5.75 3239.4 - 525980 - - - 4.7401 - 1.314 0.209 - 130.4 1 2 0 0.0044 8 0 0 0 2.23E+07 2.01E+07 - - - 1.4069 0.9885 230117_WJC_METTL3_WT_vs_EV_F01.15717.15717.2 0.00299 20-Oct R.VIGTLLGTVDK.H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1114.6598 1.09 3243 15717 2 1114.668831 558.3372 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3239.7 - 277325 - - - 8.1245 - 2.047 0.474 - 195.7 1 2 0 0.0091 11 0 0 0 1.33E+08 1.22E+08 - - - 4.4771 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.15720.15720.2 0.00218 16-Aug R.LFEGNALLR[166.11].R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1041.5847 0.87 3244 15720 2 1041.584667 521.7996 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3240.1 - 2.38E+07 - - - 0.0163 - 1.79 0.409 - 192.2 1 2 0 0 9 0 0 0 1.44E+09 1.65E+09 - - - 3.7462 1 230117_WJC_METTL3_WT_vs_EV_F01.15722.15722.2 6.25E-05 20-Nov R.VIGTLLGTVDK[136.11].H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1122.674 1.09 3246 15722 2 1122.677705 562.3443 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3240.4 - 1.68E+06 - - - 3.3224 - 2.165 0.485 - 269.3 1 2 0 0.0037 11 0 0 0 1.33E+08 1.22E+08 - - - 4.7116 0.998 230117_WJC_METTL3_WT_vs_EV_F01.15727.15727.2 0.472 14-Sep K.MLLSLPEK.V "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 929.5256 1.11 3251 15727 2 929.528721 465.7701 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 5.75 3240.9 - 1.14E+06 - - - 3.3684 - 1.831 0.228 - 286.7 1 2 0 0.0031 8 0 0 0 2.27E+07 2.05E+07 - - - 2.5483 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.15735.15735.2 0.0147 14-Jul K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 1.74 3257 15735 2 895.481638 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3241.9 - 4.31E+06 - - - 1.4339 - 1.31 0.388 - 119 1 2 0 0.0013 8 0 0 0 3.67E+09 2.12E+09 - - - 2.7208 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.15738.15738.2 3.05 14-Aug R.SLVSGLIR[166.11].L sp|Q92616|GCN1_HUMAN 1 853.5261 1.08 3260 15738 2 853.52696 427.7703 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.47 3242.2 - 1.97E+06 - - - 1.0404 - 1.611 0.154 - 238.9 1 2 0 0.0009 8 0 0 0 6.54E+07 6.05E+07 - - - 1.6163 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.15741.15741.2 0.00566 18-Oct K.LLANMVYQYK.G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1241.6478 2.17 3263 15741 2 1241.648547 621.8312 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3242.5 - 862993 - - - 0.5775 - 1.959 0.482 - 313.9 1 2 0 0.0007 10 0 0 0 3.43E+07 1.58E+07 - - - 4.4778 0.9905 230117_WJC_METTL3_WT_vs_EV_F01.15742.15742.2 1.51 14-Oct R.IAVPVLVR[166.11].D sp|P52952|NKX25_HUMAN 1 875.5832 2.13 3264 15742 2 875.584652 438.7989 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 9.75 3242.7 - 793444 - - - 1.6663 - 1.462 0.046 - 435.4 1 2 0 0.0015 8 0 0 0 2.98E+07 1.40E+07 - - - 0.5258 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.15743.15743.2 0.112 18-Aug R.IVLVDDSIVR.G sp|Q06203|PUR1_HUMAN 1 1127.655 1.78 3265 15743 2 1127.656924 564.8348 Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1 4.21 3242.8 - 617672 - - - 1.6849 - 1.85 0.166 - 217.6 1 2 0 0.0019 10 0 0 0 5.04E+07 2.83E+07 - - - 1.9836 0.999 230117_WJC_METTL3_WT_vs_EV_F01.15745.15745.2 0.00767 18-Jun R.IVLVDDSIVR[166.11].G sp|Q06203|PUR1_HUMAN 1 1137.6633 1.77 3267 15745 2 1137.664773 569.8389 Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1 4.21 3243.1 - 285544 - - - 1.3 - 1.383 0.335 - 72.1 1 2 0 0.0015 10 0 0 0 5.01E+07 2.83E+07 - - - 2.4199 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.15749.15749.2 0.161 12-Jun M.GVPAFFR[166.11].W sp|Q9H0D6|XRN2_HUMAN 1 802.4365 0.89 3269 15749 2 802.437111 402.2255 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 3243.5 - 2.47E+07 - - - 0.7253 - 1.075 0.329 - 180.2 1 2 0 0.0006 7 0 0 0 2.39E+08 2.68E+08 - - - 1.7 0.8958 230117_WJC_METTL3_WT_vs_EV_F01.15751.15751.2 0.247 12-Sep L.FGDLLLK[136.11].Q "sp|Q15147|PLCB4_HUMAN,sp|Q6P2Q9|PRP8_HUMAN,tr|A0A7P0MRI8|A0A7P0MRI8_HUMAN" 3 812.4887 1.21 3271 15751 2 812.488595 407.2516 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4 PE=1 SV=3" 5.84 3243.7 - 1.16E+06 - - - -0.1797 - 1.76 0.226 - 202 1 1 0 -0.0001 7 0 0 0 1.96E+08 1.62E+08 - - - 2.5014 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.15752.15752.2 0.000154 18-Nov K.LLANMVYQYK[136.11].G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1249.662 2.19 3272 15752 2 1249.663486 625.8383 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3243.8 - 1.05E+06 - - - 1.1651 - 1.85 0.411 - 302.5 1 2 0 0.0015 10 0 0 0 3.43E+07 1.57E+07 - - - 3.7934 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.15753.15753.2 0.00553 14-Aug K.VFNLGVYR.R "sp|O60825|F262_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN" 2 966.5287 0.59 3273 15753 2 966.532791 484.2716 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 8.72 3243.9 - 650415 - - - 4.2316 - 1.551 0.282 - 192.2 1 2 0 0.0041 8 0 0 0 3.58E+07 6.08E+07 - - - 2.4463 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.15758.15758.2 0.18 14-Jul R.IAVPVLVR.D sp|P52952|NKX25_HUMAN 1 865.5749 2.05 3276 15758 2 865.575341 433.7947 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 9.75 3244.4 - 3.26E+06 - - - 0.4829 - 1.462 0.209 - 197.1 1 2 0 0.0004 8 0 0 0 2.88E+07 1.40E+07 - - - 1.73 0.9946 230117_WJC_METTL3_WT_vs_EV_F01.15760.15760.2 0.821 14-Jul K.NLYIISVK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 956.5786 1.27 3278 15760 2 956.579484 479.2966 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3244.6 - 1.58E+06 - - - 0.9053 - 1.387 0.124 - 152.6 1 2 0 0.0009 8 0 0 0 3.05E+09 2.39E+09 - - - 0.9432 1 230117_WJC_METTL3_WT_vs_EV_F01.15761.15761.2 7.17E-06 20-Dec R.LFSGDVVLTAR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1186.6585 0.98 3279 15761 2 1186.660261 594.3365 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3244.7 - 1.06E+06 - - - 1.4478 - 2.253 0.519 - 442.1 1 2 0 0.0017 11 0 0 0 2.28E+08 2.34E+08 - - - 5.0712 0.999 230117_WJC_METTL3_WT_vs_EV_F01.15762.15762.2 0.000176 26-Oct K.VLEQLTGQTPVFSK.A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1545.8403 1.43 3280 15762 2 1545.845698 773.9274 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3244.9 - 882499 - - - 3.5185 - 1.923 0.404 - 128 1 2 0 0.0054 14 0 0 0 8.38E+06 5.84E+06 - - - 3.6641 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.15764.15764.2 0.000876 22-Oct R.VLVTGATGLLGR[166.11].A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1165.7058 1.45 3282 15764 2 1165.707039 583.8602 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3245.1 - 495859 - - - 1.0389 - 1.802 0.419 - 260.1 1 2 0 0.0012 12 0 0 0 2.64E+07 1.83E+07 - - - 3.6848 1 230117_WJC_METTL3_WT_vs_EV_F01.15765.15765.2 1.35E-05 26-Oct K.VLEQLTGQTPVFSK[136.11].A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1553.8545 1.43 3283 15765 2 1553.853816 777.9345 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3245.3 - 400978 - - - -0.4138 - 2.215 0.491 - 318.2 1 2 0 -0.0006 14 0 0 0 8.38E+06 5.84E+06 - - - 4.663 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.15770.15770.2 0.0249 14-Sep K.NLYIISVK.G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 948.5644 1.27 3286 15770 2 948.565408 475.2895 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3246 - 7.55E+06 - - - 1.0437 - 1.573 0.214 - 335.9 1 2 0 0.001 8 0 0 0 3.05E+09 2.39E+09 - - - 1.9875 1 230117_WJC_METTL3_WT_vs_EV_F01.15771.15771.2 4.91E-05 13/20 R.LFSGDVVLTAR.D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1176.6503 0.98 3287 15771 2 1176.650843 589.3324 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3246.1 - 2.47E+06 - - - 0.4844 - 2.384 0.556 - 537.9 1 2 0 0.0006 11 0 0 0 2.29E+08 2.34E+08 - - - 5.4977 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.15773.15773.2 0.067 14-Jul R.FVDGLTFK.V "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 925.4909 0.91 3289 15773 2 925.490763 463.7527 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.84 3246.3 - 1.68E+06 - - - -0.1686 - 1.345 0.306 - 126 1 2 0 -0.0002 8 0 0 0 1.80E+07 1.99E+07 - - - 2.195 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.15774.15774.2 0.102 14-Jul R.LLPSLIGR[166.11].H "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 4 877.5625 0.73 3290 15774 2 877.563372 439.7885 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 9.75 3246.4 - 1.18E+06 - - - 1.0415 - 1.382 0.237 - 172.1 1 2 0 0.0009 8 0 0 0 6.25E+07 8.62E+07 - - - 1.767 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.15775.15775.2 0.0221 22-Nov R.VLVTGATGLLGR.A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1155.6976 1.45 3291 15775 2 1155.698188 578.8561 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3246.6 - 640134 - - - 0.5451 - 1.791 0.345 - 303 1 2 0 0.0006 12 0 0 0 2.64E+07 1.83E+07 - - - 3.1223 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.15779.15779.2 0.000332 14-Aug K.FVADGIFK[136.11].A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 903.4946 1.74 3293 15779 2 903.495303 452.7546 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3247 - 3.25E+07 - - - 0.829 - 1.71 0.443 - 149.7 1 2 0 0.0007 8 0 0 0 3.67E+09 2.12E+09 - - - 3.9308 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.15787.15787.2 0.484 14-Aug K.VFNLGVYR[166.11].R "sp|O60825|F262_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN" 2 976.537 0.58 3300 15787 2 976.537253 489.2758 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 8.72 3247.8 - 4.73E+06 - - - 0.2888 - 1.716 0.182 - 213.5 1 2 0 0.0003 8 0 0 0 3.48E+07 6.01E+07 - - - 2.0138 0.9789 230117_WJC_METTL3_WT_vs_EV_F01.15789.15789.2 3.3 16-Jul K.EALEAVLIK[136.11].G "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 992.5997 1.35 3301 15789 2 992.60147 497.3072 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 4.53 3248 - 240890 - - - 1.7348 - 1.106 0.089 - 105.6 1 2 0 0.0017 9 0 0 0 1.85E+07 1.37E+07 - - - -0.0107 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.15791.15791.2 0.000654 14-Sep R.LFC[160.03]VGFTK.K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 970.4946 0.83 3303 15791 2 970.496409 486.2546 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.22 3248.2 - 1.35E+06 - - - 1.8393 - 1.794 0.354 - 223.1 1 2 0 0.0018 8 0 0 0 3.55E+08 4.28E+08 - - - 3.4178 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.15796.15796.2 0.0874 14-Jul R.LLPSLIGR.H "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 4 867.5542 0.73 3306 15796 2 867.554507 434.7844 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 9.75 3248.7 - 1.58E+06 - - - 0.3677 - 1.433 0.283 - 188.6 1 2 0 0.0003 8 0 0 0 6.25E+07 8.61E+07 - - - 2.2162 0.9906 230117_WJC_METTL3_WT_vs_EV_F01.15798.15798.2 0.354 12-Jun R.GFFNGLR[166.11].T "sp|Q9Y394|DHRS7_HUMAN,tr|H0YJ66|H0YJ66_HUMAN,tr|H0YJE4|H0YJE4_HUMAN,tr|H0YJR8|H0YJR8_HUMAN" 4 819.4267 1.33 3308 15798 2 819.427983 410.7206 Dehydrogenase\reductase SDR family member 7 OS=Homo sapiens OX=9606 GN=DHRS7 PE=1 SV=1 9.75 3248.9 - 432405 - - - 1.5743 - 1.253 0.104 - 121.4 1 2 0 0.0013 7 0 0 0 1.13E+07 8.51E+06 - - - 0.5234 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.15802.15802.2 0.0168 22-Aug K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.42 3311 15802 2 1287.76255 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3249.4 - 341994 - - - 3.6397 - 1.571 0.227 - 97.9 1 2 0 0.0047 12 0 0 0 3.10E+07 2.18E+07 - - - 1.9047 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.15804.15804.2 1.15 14-Aug K.TAVLTLIR.E "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 8 885.5648 1.4 3312 15804 2 885.566597 443.7897 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 9.41 3249.6 - 4.99E+06 - - - 2.0823 - 1.729 0.17 - 363.1 1 2 0 0.0018 8 0 0 0 1.33E+08 9.52E+07 - - - 1.9474 0.9688 230117_WJC_METTL3_WT_vs_EV_F01.15806.15806.2 0.194 14-Jul R.TVETLLLR.F "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 6 943.5702 0.57 3314 15806 2 943.571728 472.7924 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 5.66 3249.8 - 786065 - - - 1.5855 - 1.21 0.014 - 150.8 1 2 0 0.0015 8 0 0 0 7.71E+07 1.35E+08 - - - -0.2812 0.9717 230117_WJC_METTL3_WT_vs_EV_F01.15812.15812.2 1.69 14-Jun K.AVIELLEK[136.11].S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|H0Y327|H0Y327_HUMAN,tr|Q5JYA8|Q5JYA8_HUMAN,tr|Q5JYA3|Q5JYA3_HUMAN" 6 921.5626 2.48 3318 15812 2 921.562028 461.7886 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.53 3250.6 - 523263 - - - -0.6576 - 1.452 0.058 - 91.3 5 2 0 -0.0006 8 0 0 0 5.24E+07 2.11E+07 - - - 0.2817 0.8818 230117_WJC_METTL3_WT_vs_EV_F01.15819.15819.2 4.45 12-May K.VLFTC[160.03]FK[136.11].R "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 921.4874 1.98 3323 15819 2 921.487995 461.751 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 8.19 3251.3 - 1.61E+06 - - - 0.688 - 0.952 0.043 - 64.2 5 2 0 0.0006 7 0 0 0 2.77E+07 1.40E+07 - - - -1.1097 0.9914 230117_WJC_METTL3_WT_vs_EV_F01.15821.15821.2 0.973 14-Jul R.FLGGVFSK.R "sp|Q9NQV6|PRD10_HUMAN,tr|E9PLV1|E9PLV1_HUMAN" 2 853.4698 0.33 3325 15821 2 853.469707 427.7422 PR domain zinc finger protein 10 OS=Homo sapiens OX=9606 GN=PRDM10 PE=1 SV=3 8.75 3251.5 - 543852 - - - -0.0973 - 1.1 0.212 - 110.7 1 2 0 -0.0001 8 0 0 0 1.43E+07 4.40E+07 - - - 0.8943 0.9843 230117_WJC_METTL3_WT_vs_EV_F01.15840.15840.2 0.655 18-Sep K.ATLLLESGIR.L "sp|O60524|NEMF_HUMAN,tr|G3V547|G3V547_HUMAN,tr|G3V5V3|G3V5V3_HUMAN,tr|G3V4D9|G3V4D9_HUMAN" 4 1071.6288 1.1 3337 15840 2 1071.634217 536.8217 Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4 6.05 3253.9 - 207864 - - - 5.0465 - 1.6 0.174 - 165.7 1 2 0 0.0054 10 0 0 0 6.45E+06 5.88E+06 - - - 1.6364 0.8794 230117_WJC_METTL3_WT_vs_EV_F01.15841.15841.2 0.562 18-May R.LIYTAGGYFR[166.11].Q sp|Q14145|KEAP1_HUMAN 1 1169.6109 1.85 3338 15841 2 1169.617282 585.8127 Kelch-like ECH-associated protein 1 OS=Homo sapiens OX=9606 GN=KEAP1 PE=1 SV=2 8.59 3254 - 203123 - - - 5.4864 - 1.213 0.109 - 56.6 2 2 0 0.0064 10 0 0 0 1.05E+07 5.66E+06 - - - 0.2486 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.15845.15845.2 0.00171 14-Jul R.ELYPVEFR.N "sp|Q5BJF2|SGMR2_HUMAN,tr|J3KT68|J3KT68_HUMAN" 2 1051.5338 1.07 3340 15845 2 1051.531709 526.7742 Sigma intracellular receptor 2 OS=Homo sapiens OX=9606 GN=TMEM97 PE=1 SV=1 4.53 3254.6 - 502056 - - - -2.0323 - 1.453 0.368 - 222 1 2 0 -0.0021 8 0 0 0 2.09E+07 1.95E+07 - - - 2.8852 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.15847.15847.2 0.000687 18-Aug R.LVPLQEEIYR.K "sp|Q2NKX8|ERC6L_HUMAN,tr|B5MDQ0|B5MDQ0_HUMAN" 2 1258.6921 3.88 3341 15847 2 1258.693316 630.3533 DNA excision repair protein ERCC-6-like OS=Homo sapiens OX=9606 GN=ERCC6L PE=1 SV=1 4.53 3254.8 - 454811 - - - 0.9359 - 1.691 0.372 - 309.9 1 2 0 0.0012 10 0 0 0 6.57E+06 1.69E+06 - - - 3.2546 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.15850.15850.2 0.0902 14-Jun K.EMVELPLR.H "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN" 10 985.5267 0.65 3343 15850 2 985.526356 493.7706 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.53 3255 - 979160 - - - -0.3014 - 1.432 0.268 - 95.5 1 2 0 -0.0003 8 0 0 0 1.34E+07 2.05E+07 - - - 2.1033 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.15851.15851.2 0.468 16-Sep R.ILPQDVILK[136.11].F "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1045.6627 0.88 3344 15851 2 1045.663001 523.8386 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.84 3255.1 - 1.52E+06 - - - 0.3051 - 1.426 0.229 - 159.1 1 2 0 0.0003 9 0 0 0 2.94E+07 3.35E+07 - - - 1.759 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.15852.15852.2 1.01 12-Aug R.LSAILFK.L "sp|Q9NSV4|DIAP3_HUMAN,sp|Q12830|BPTF_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|J3KSK9|J3KSK9_HUMAN,tr|J3QQQ8|J3QQQ8_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN" 7 790.4953 2.26 3345 15852 2 790.497089 396.2549 Protein diaphanous homolog 3 OS=Homo sapiens OX=9606 GN=DIAPH3 PE=1 SV=4 8.75 3255.2 - 700045 - - - 2.2935 - 1.791 0.113 - 154.2 1 2 0 0.0018 7 0 0 0 1.18E+07 5.21E+06 - - - 1.7216 0.998 230117_WJC_METTL3_WT_vs_EV_F01.15857.15857.2 0.139 14-Aug K.LVWIPSER.H "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 998.5549 0.84 3348 15857 2 998.555544 500.2847 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3255.9 - 894955 - - - 0.6289 - 1.492 0.215 - 171.6 1 2 0 0.0006 8 0 0 0 6.44E+07 7.68E+07 - - - 1.8355 0.9935 230117_WJC_METTL3_WT_vs_EV_F01.15858.15858.2 0.293 16-Aug R.FFMGNQVLK.V sp|P13010|XRCC5_HUMAN 1 1082.5583 0.82 3349 15858 2 1082.557655 542.2864 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3256 - 569903 - - - -0.5838 - 1.254 0.223 - 133.7 1 2 0 -0.0006 9 0 0 0 6.20E+07 7.61E+07 - - - 1.3427 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.15859.15859.2 0.0151 18-Oct R.GLIENPALLR[166.11].W sp|O95168|NDUB4_HUMAN 1 1104.6531 1.16 3350 15859 2 1104.658382 553.3338 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3 6 3256.1 - 320156 - - - 4.8142 - 2.115 0.276 - 246.5 1 2 0 0.0053 10 0 0 0 3.70E+07 3.20E+07 - - - 3.1687 0.913 230117_WJC_METTL3_WT_vs_EV_F01.15860.15860.2 1.07 16-Jun R.ADILQVGLR.E "sp|Q9H074|PAIP1_HUMAN,tr|D6RJF2|D6RJF2_HUMAN,tr|D6REB4|D6REB4_HUMAN" 3 983.5764 4.41 3351 15860 2 983.58166 492.7955 Polyadenylate-binding protein-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAIP1 PE=1 SV=1 5.88 3256.2 - 1.16E+06 - - - 5.3682 - 1.249 0.121 - 58.9 2 2 0 0.0053 9 0 0 0 1.19E+07 2.71E+06 - - - 0.4418 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.15865.15865.2 0.102 16-Aug R.FFMGNQVLK[136.11].V sp|P13010|XRCC5_HUMAN 1 1090.5725 0.81 3354 15865 2 1090.57429 546.2935 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3256.8 - 770747 - - - 1.6533 - 1.364 0.308 - 123.9 1 2 0 0.0018 9 0 0 0 6.20E+07 7.61E+07 - - - 2.2134 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.15867.15867.2 9.07E-05 20-Oct K.MVLSGC[160.03]AIIVR.G sp|Q7KZF4|SND1_HUMAN 1 1217.6624 1.63 3356 15867 2 1217.667832 609.8385 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 8 3257.1 - 311992 - - - 4.4323 - 1.895 0.384 - 331.4 1 2 0 0.0054 11 0 0 0 2.74E+06 1.68E+06 - - - 3.6048 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.15878.15878.2 0.00463 18-Sep R.GLIENPALLR.W sp|O95168|NDUB4_HUMAN 1 1094.6448 1.16 3363 15878 2 1094.647262 548.3297 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3 6 3258.4 - 864086 - - - 2.2546 - 2.012 0.198 - 192 1 2 0 0.0025 10 0 0 0 3.70E+07 3.20E+07 - - - 2.4541 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.15881.15881.2 0.0744 18-Jul K.IVMETVPVLK[136.11].A "sp|Q9Y6K9|NEMO_HUMAN,tr|A0A087X1B1|A0A087X1B1_HUMAN,tr|A0A087WUW6|A0A087WUW6_HUMAN,tr|A0A087X0G7|A0A087X0G7_HUMAN" 4 1135.6766 4.91 3366 15881 2 1135.679469 568.8456 NF-kappa-B essential modulator OS=Homo sapiens OX=9606 GN=IKBKG PE=1 SV=2 6 3258.8 - 121156 - - - 2.5104 - 1.438 0.25 - 96.4 1 2 0 0.0029 10 0 0 0 1.62E+07 3.31E+06 - - - 1.9006 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.15884.15884.2 0.0434 16-Oct R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 0.75 3367 15884 2 960.611492 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3259.2 - 1.00E+07 - - - 1.6385 - 1.962 0.223 - 309.1 1 2 0 0.0016 9 0 0 0 1.30E+10 1.74E+10 - - - 2.6374 0.8855 230117_WJC_METTL3_WT_vs_EV_F01.15885.15885.2 1.41 14-Jun K.FVIPLHSA.- sp|Q96F86|EDC3_HUMAN 1 882.4963 - 3368 15885 2 882.500348 442.2554 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 6.74 3259.3 - 952690 - - - 4.5428 - 1.175 0.046 - 115.3 1 2 0 0.004 8 0 0 0 - - - - - -0.1341 0.9832 230117_WJC_METTL3_WT_vs_EV_F01.15892.15892.2 0.696 12-Aug K.SIELFYK[136.11].F sp|P78527|PRKDC_HUMAN 1 906.4942 0.37 3373 15892 2 906.493919 454.2544 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.72 3260.2 - 1.15E+06 - - - -0.332 - 1.136 0.144 - 218 1 2 0 -0.0003 7 0 0 0 3.16E+07 8.58E+07 - - - 0.5085 0.9519 230117_WJC_METTL3_WT_vs_EV_F01.15893.15893.2 0.0325 18-Sep H.ILSPWGAEVK[136.11].A "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1106.6215 1.1 3374 15893 2 1106.622424 554.318 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3260.3 - 994578 - - - 0.7934 - 1.759 0.321 - 169.7 1 1 0 0.0009 10 0 0 0 9.43E+07 8.56E+07 - - - 2.988 0.9875 230117_WJC_METTL3_WT_vs_EV_F01.15894.15894.2 0.473 12-Jul K.SIELFYK.F sp|P78527|PRKDC_HUMAN 1 898.48 0.35 3375 15894 2 898.481352 450.2473 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.72 3260.3 - 1.08E+06 - - - 1.4825 - 1.053 0.151 - 154.9 1 2 0 0.0013 7 0 0 0 2.99E+07 8.48E+07 - - - 0.3195 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.15897.15897.2 0.000315 16-Jun K.VLPVGVLYK.V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 986.6165 0.54 3378 15897 2 986.618343 494.3155 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3260.7 - 182159 - - - 1.9146 - 1.465 0.403 - 79.1 1 2 0 0.0019 9 0 0 0 1.30E+08 2.41E+08 - - - 3.1217 0.9931 230117_WJC_METTL3_WT_vs_EV_F01.15898.15898.2 0.0171 20-Aug K.FSPAGPVLSIR[166.11].V "sp|Q13310|PABP4_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN" 4 1152.6531 1.26 3379 15898 2 1152.650333 577.3338 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.75 3260.8 - 121974 - - - -2.3693 - 1.386 0.325 - 113.7 1 2 0 -0.0027 11 0 0 0 1.31E+07 1.04E+07 - - - 2.3236 0.9033 230117_WJC_METTL3_WT_vs_EV_F01.15901.15901.4 0.234 15/96 T.LLLIILTDVFIISTVLR.L sp|Q8NGY0|O10X1_HUMAN 1 1941.2278 999 3380 15901 4 1941.23633 486.3142 Olfactory receptor 10X1 OS=Homo sapiens OX=9606 GN=OR10X1 PE=3 SV=2 5.84 3261.3 - 763493 - - - 4.3828 - 1.908 0.293 - 107.1 1 1 0 0.0085 17 0 0 0 2.27E+07 0.00E+00 - - - 1.9982 0.9567 230117_WJC_METTL3_WT_vs_EV_F01.15904.15904.2 7.87 14-Jun K.GLVAVGER[166.11].A "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 3 809.4635 1.42 3383 15904 2 809.465116 405.739 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3261.6 - 599160 - - - 2.031 - 1.219 0.009 - 88.7 2 2 0 0.0016 8 0 0 0 2.29E+07 1.61E+07 - - - -0.4303 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.15911.15911.2 0.485 12-Jul R.VLAAFLR.R "sp|Q9HB09|B2L12_HUMAN,sp|Q99607|ELF4_HUMAN,tr|M0R1Z8|M0R1Z8_HUMAN,tr|A0A087WU18|A0A087WU18_HUMAN,tr|I6LJZ9|I6LJZ9_HUMAN,tr|A0A087WSV0|A0A087WSV0_HUMAN,tr|I6LK00|I6LK00_HUMAN,tr|I6LJZ7|I6LJZ7_HUMAN,tr|M0R1K0|M0R1K0_HUMAN,tr|M0QZM6|M0QZM6_HUMAN" 10 788.4909 3.67 3388 15911 2 788.492587 395.2527 Bcl-2-like protein 12 OS=Homo sapiens OX=9606 GN=BCL2L12 PE=1 SV=1 9.72 3262.5 - 2.37E+06 - - - 2.1915 - 1.491 0.119 - 141.4 1 2 0 0.0017 7 0 0 0 3.66E+07 9.96E+06 - - - 1.1851 0.9292 230117_WJC_METTL3_WT_vs_EV_F01.15915.15915.2 1.3 22-May K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 2.17 3391 15915 2 1277.748712 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3262.9 - 248626 - - - -0.6895 - 1.312 0.09 - 36.8 47 2 0 -0.0009 12 0 0 0 7.88E+06 3.63E+06 - - - -0.327 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.15917.15917.2 0.00684 18-Oct K.IGDLGLATLK.R "sp|Q9H4A3|WNK1_HUMAN,sp|Q96J92|WNK4_HUMAN,sp|Q9Y3S1|WNK2_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A6PVV2|A6PVV2_HUMAN,tr|K7ENT7|K7ENT7_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 9 999.5964 1.94 3392 15917 2 999.597757 500.8055 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 5.84 3263.2 - 6.65E+06 - - - 1.3105 - 2.18 0.348 - 173.7 1 2 0 0.0013 10 0 0 0 1.22E+08 6.32E+07 - - - 3.7862 0.9913 230117_WJC_METTL3_WT_vs_EV_F01.15919.15919.2 1.09 12-Jun K.AFLFVNK.G sp|Q8N0X7|SPART_HUMAN 1 837.4749 1.59 3394 15919 2 837.475078 419.7447 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3263.3 - 2.16E+07 - - - 0.2424 - 1.214 0.149 - 187.4 1 2 0 0.0002 7 0 0 0 2.22E+08 1.40E+08 - - - 0.7559 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.15922.15922.2 0.0341 14-Aug K.YFEYIMAK.E sp|P13674|P4HA1_HUMAN 1 1063.5049 2.68 3397 15922 2 1063.504884 532.7597 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3263.5 - 1.78E+06 - - - 0.0282 - 1.43 0.276 - 180.7 1 2 0 0 8 0 0 0 6.30E+07 2.35E+07 - - - 2.1583 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.15925.15925.2 0.103 16-Jul R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 0.75 3399 15925 2 952.598248 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3263.9 - 9.65E+07 - - - 2.6559 - 1.215 0.267 - 155.9 1 2 0 0.0025 9 0 0 0 1.30E+10 1.74E+10 - - - 1.5757 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.15927.15927.2 0.0207 20-Aug K.FSPAGPVLSIR.V "sp|Q13310|PABP4_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN" 4 1142.6448 1.26 3400 15927 2 1142.647226 572.3297 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.75 3264.1 - 533089 - - - 2.1284 - 1.486 0.288 - 155.2 1 2 0 0.0024 11 0 0 0 1.31E+07 1.04E+07 - - - 2.2389 1 230117_WJC_METTL3_WT_vs_EV_F01.15933.15933.3 1.05E-06 20/64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 26.62 3404 15933 3 1786.982575 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3264.8 - 322009 - - - -0.1819 - 3.63 0.509 - 376.3 1 2 0 -0.0003 17 0 0 0 7.72E+07 2.90E+06 - - - 7.4717 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.15934.15934.2 0.0475 12-Jul K.AFLFVNK[136.11].G sp|Q8N0X7|SPART_HUMAN 1 845.4891 1.59 3405 15934 2 845.490147 423.7518 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3264.8 - 2.67E+06 - - - 1.2679 - 1.256 0.253 - 202.1 1 2 0 0.0011 7 0 0 0 2.21E+08 1.40E+08 - - - 1.6315 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.15941.15941.2 0.00178 12-Jul K.QC[160.03]FLVLR.Q "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|H7C278|H7C278_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 5 934.5059 0.57 3410 15941 2 934.50738 468.2602 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 8.25 3265.5 - 1.78E+06 - - - 1.6287 - 1.432 0.386 - 263.9 1 2 0 0.0015 7 0 0 0 3.30E+07 5.79E+07 - - - 3.0293 0.8674 230117_WJC_METTL3_WT_vs_EV_F01.15950.15950.2 4.1 16-May K.VDIEAIFSK.Y "sp|Q86SE5|RALYL_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 4 1020.5492 4.44 3417 15950 2 1020.547938 511.2819 RNA-binding Raly-like protein OS=Homo sapiens OX=9606 GN=RALYL PE=1 SV=2 4.37 3266.6 - 1.41E+06 - - - -1.1994 - 1.169 0.04 - 43.1 6 2 0 -0.0012 9 0 0 0 1.50E+07 3.37E+06 - - - -0.5598 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.15958.15958.2 0.026 14-Aug K.GIAYIEFK[136.11].T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 947.5208 0.78 3422 15958 2 947.519804 474.7677 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3267.5 - 1.20E+07 - - - -1.0184 - 1.505 0.258 - 204.9 1 2 0 -0.001 8 0 0 0 5.98E+08 7.69E+08 - - - 2.1792 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.15965.15965.2 0.00439 14-Aug K.YFEYIMAK[136.11].E sp|P13674|P4HA1_HUMAN 1 1071.5191 2.67 3428 15965 2 1071.519716 536.7668 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3268.2 - 1.22E+06 - - - 0.6178 - 1.406 0.378 - 176.5 1 2 0 0.0007 8 0 0 0 6.29E+07 2.35E+07 - - - 2.8604 0.9911 230117_WJC_METTL3_WT_vs_EV_F01.15968.15968.2 0.993 12-Jul R.VLQLFTR[166.11].L "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 885.5312 1.11 3429 15968 2 885.530241 443.7729 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 9.72 3268.6 - 1.85E+06 - - - -1.0355 - 1.394 0.166 - 164.6 1 2 0 -0.0009 7 0 0 0 4.53E+07 4.07E+07 - - - 1.3193 0.867 230117_WJC_METTL3_WT_vs_EV_F01.15973.15973.2 2.36 12-Jun K.ILIWSGR.F "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 843.4967 1.49 3432 15973 2 843.492947 422.7556 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 9.75 3269.2 - 699218 - - - -4.4173 - 1.324 0.115 - 123.3 1 2 0 -0.0037 7 0 0 0 7.79E+07 5.22E+07 - - - 0.7785 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.15975.15975.2 0.00246 14-Sep K.GIAYIEFK.T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 939.5066 0.79 3433 15975 2 939.507583 470.7606 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3269.4 - 3.31E+07 - - - 1.0793 - 1.803 0.158 - 271.1 1 2 0 0.001 8 0 0 0 6.09E+08 7.70E+08 - - - 1.9854 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.15981.15981.2 0.00301 16-Sep R.VFNPYTEFK.E sp|Q96C19|EFHD2_HUMAN 1 1143.5601 1.56 3436 15981 2 1143.559129 572.7873 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 5.97 3270.1 - 541197 - - - -0.815 - 1.627 0.345 - 234 1 2 0 -0.0009 9 0 0 0 2.04E+07 1.31E+07 - - - 2.997 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.15985.15985.2 0.00334 16-Sep R.LLLQLEATK.N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1027.6277 11.68 3438 15985 2 1027.625635 514.8211 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3270.6 - 1.35E+06 - - - -2.0552 - 2.013 0.378 - 234.6 1 2 0 -0.0021 9 0 0 0 9.42E+08 8.07E+07 - - - 3.8563 0.9956 230117_WJC_METTL3_WT_vs_EV_F01.15986.15986.2 1.56 14-Oct R.TLINELVK.G "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 7 928.5593 1.11 3439 15986 2 928.56018 465.2869 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.66 3270.7 - 401282 - - - 0.9122 - 1.414 0.138 - 247.7 1 2 0 0.0008 8 0 0 0 9.26E+07 8.33E+07 - - - 1.1048 0.9539 230117_WJC_METTL3_WT_vs_EV_F01.15990.15990.2 1.23 12-Jul K.ILIEDWK[136.11].K "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A7I2V2T6|A0A7I2V2T6_HUMAN,tr|K7EPW7|K7EPW7_HUMAN" 4 923.5208 1.27 3443 15990 2 923.524308 462.7677 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 4.37 3271.1 - 793393 - - - 3.8321 - 1.348 0.027 - 132.4 1 2 0 0.0035 7 0 0 0 3.09E+07 2.44E+07 - - - 0.1855 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.15996.15996.2 0.84 12-Jul K.ILIWSGR[166.11].F "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 853.5049 1.48 3447 15996 2 853.505562 427.7597 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 9.75 3271.9 - 1.51E+06 - - - 0.7252 - 1.449 0.226 - 151.8 1 2 0 0.0006 7 0 0 0 7.73E+07 5.22E+07 - - - 1.8852 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.15998.15998.2 0.0169 16-Aug R.MNVLADALK.S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 973.5267 1.37 3449 15998 2 973.527146 487.7706 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3272 - 1.01E+06 - - - 0.5064 - 2.041 0.384 - 221 1 2 0 0.0005 9 0 0 0 7.63E+08 5.59E+08 - - - 3.9411 1 230117_WJC_METTL3_WT_vs_EV_F01.15999.15999.2 0.000826 16-Oct R.MNVLADALK[136.11].S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 981.5409 1.37 3450 15999 2 981.541978 491.7777 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3272.1 - 666831 - - - 1.1462 - 2.215 0.441 - 417.6 1 2 0 0.0011 9 0 0 0 7.63E+08 5.58E+08 - - - 4.5986 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.16004.16004.2 0.129 16-Aug R.LLLQLEATK[136.11].N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1035.6419 11.01 3453 16004 2 1035.641368 518.8282 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3272.7 - 1.01E+07 - - - -0.5591 - 1.824 0.347 - 162.7 1 2 0 -0.0006 9 0 0 0 9.45E+08 8.58E+07 - - - 3.3426 0.992 230117_WJC_METTL3_WT_vs_EV_F01.16008.16008.2 0.237 12-Jul R.LYDGLFK.V "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 10 854.4538 1.77 3457 16008 2 854.453868 428.2342 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.83 3273 - 3.79E+06 - - - 0.0737 - 1.18 0.178 - 105.3 1 2 0 0.0001 7 0 0 0 2.18E+08 1.23E+08 - - - 0.8801 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.16012.16012.2 0.00648 20-Aug K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.14 3461 16012 2 1235.759767 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3273.5 - 2.29E+06 - - - -0.3164 - 1.84 0.336 - 189.4 1 2 0 -0.0004 11 0 0 0 6.43E+08 5.66E+08 - - - 3.1721 0.9615 230117_WJC_METTL3_WT_vs_EV_F01.16013.16013.2 1.26 12-Jun R.LLLAFQK.K sp|Q14781|CBX2_HUMAN 1 831.5218 1.46 3462 16013 2 831.521723 416.7682 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.75 3273.7 - 1.98E+06 - - - -0.1227 - 1.17 0.062 - 86.4 2 2 0 -0.0001 7 0 0 0 4.10E+07 2.81E+07 - - - -0.1381 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.16019.16019.2 0.38 12-May R.LFFVGSR.E "sp|Q9UM01|YLAT1_HUMAN,sp|Q92536|YLAT2_HUMAN,sp|Q01650|LAT1_HUMAN,tr|H0YJ95|H0YJ95_HUMAN,tr|A0A0C4DGL4|A0A0C4DGL4_HUMAN,tr|G3V4Z6|G3V4Z6_HUMAN" 6 824.4545 0.96 3466 16019 2 824.456374 413.2345 Y+L amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A7 PE=1 SV=2 9.75 3274.4 - 582493 - - - 2.3046 - 1.346 0.214 - 72.6 3 2 0 0.0019 7 0 0 0 3.52E+07 3.66E+07 - - - 1.3494 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.16021.16021.2 0.0693 20-Nov K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.14 3468 16021 2 1245.771315 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3274.7 - 2.02E+06 - - - 2.3174 - 1.719 0.298 - 213.9 1 2 0 0.0029 11 0 0 0 6.41E+08 5.64E+08 - - - 2.7067 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.16023.16023.2 0.0202 18-Sep K.ILPEEITNLR.N sp|Q9H9A6|LRC40_HUMAN 1 1196.6765 1.01 3470 16023 2 1196.67782 599.3455 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3275 - 1.53E+06 - - - 1.1131 - 1.747 0.335 - 338.2 1 2 0 0.0013 10 0 0 0 5.50E+07 5.46E+07 - - - 3.0722 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.16025.16025.2 0.0387 14-Sep K.AVWLPAVK.A "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 882.5327 1.43 3472 16025 2 882.533383 442.2736 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.8 3275.2 - 666182 - - - 0.7467 - 1.529 0.186 - 282.8 1 2 0 0.0007 8 0 0 0 4.36E+07 3.05E+07 - - - 1.6952 0.9906 230117_WJC_METTL3_WT_vs_EV_F01.16028.16028.2 0.0799 16-Jul K.VIIDTLITK[136.11].L sp|O15164|TIF1A_HUMAN 1 1022.6467 1.71 3475 16028 2 1022.645964 512.3306 Transcription intermediary factor 1-alpha OS=Homo sapiens OX=9606 GN=TRIM24 PE=1 SV=3 5.81 3275.6 - 380424 - - - -0.7177 - 1.322 0.171 - 81.6 1 2 0 -0.0007 9 0 0 0 1.28E+07 7.51E+06 - - - 1.1114 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.16033.16033.2 0.252 12-Jun R.LYDGLFK[136.11].V "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 10 862.468 1.82 3478 16033 2 862.46894 432.2413 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.83 3276.1 - 8.10E+06 - - - 1.0841 - 1.272 0.219 - 104.3 1 2 0 0.0009 7 0 0 0 2.32E+08 1.28E+08 - - - 1.4206 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.16036.16036.2 0.000302 18-Sep K.ILPEEITNLR[166.11].N sp|Q9H9A6|LRC40_HUMAN 1 1206.6848 2.03 3481 16036 2 1206.686661 604.3497 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3276.4 - 1.38E+06 - - - 1.577 - 1.745 0.415 - 298.3 1 2 0 0.0019 10 0 0 0 5.13E+07 2.52E+07 - - - 3.6597 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.16037.16037.2 0.000509 20-Dec R.LVDAVLGAEIR[166.11].N "sp|Q9UBN7|HDAC6_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8Y758|A0A2R8Y758_HUMAN,tr|A0A2R8Y559|A0A2R8Y559_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 5 1164.6742 0.88 3482 16037 2 1164.677262 583.3444 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.37 3276.5 - 708402 - - - 2.6351 - 2.109 0.337 - 203.9 1 2 0 0.0031 11 0 0 0 7.58E+07 8.65E+07 - - - 3.5478 0.999 230117_WJC_METTL3_WT_vs_EV_F01.16041.16041.2 0.0425 14-Oct R.TLINELVK[136.11].G "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 7 936.5735 1.15 3484 16041 2 936.574427 469.294 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.66 3277 - 5.91E+06 - - - 0.9545 - 1.646 0.254 - 257 1 2 0 0.0009 8 0 0 0 9.69E+07 8.45E+07 - - - 2.4198 0.9952 230117_WJC_METTL3_WT_vs_EV_F01.16042.16042.2 0.47 12-Jul R.LFFVGSR[166.11].E "sp|Q9UM01|YLAT1_HUMAN,sp|Q92536|YLAT2_HUMAN,sp|Q01650|LAT1_HUMAN,tr|H0YJ95|H0YJ95_HUMAN,tr|A0A0C4DGL4|A0A0C4DGL4_HUMAN,tr|G3V4Z6|G3V4Z6_HUMAN" 6 834.4627 1.04 3485 16042 2 834.462459 418.2386 Y+L amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A7 PE=1 SV=2 9.75 3277.1 - 1.83E+06 - - - -0.3415 - 1.437 0.172 - 187.3 1 2 0 -0.0003 7 0 0 0 3.86E+07 3.73E+07 - - - 1.4601 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.16043.16043.2 0.134 18-Sep R.LAWGQPVGLR.H "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQX9|A0A0U1RQX9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 7 1095.6189 4.66 3486 16043 2 1095.621237 548.8167 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 9.75 3277.2 - 2.96E+06 - - - 2.1212 - 1.795 0.308 - 220.8 1 2 0 0.0023 10 0 0 0 1.09E+08 2.33E+07 - - - 2.9481 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.16044.16044.2 0.000517 20-Oct R.LVDAVLGAEIR.N "sp|Q9UBN7|HDAC6_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8Y758|A0A2R8Y758_HUMAN,tr|A0A2R8Y559|A0A2R8Y559_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 5 1154.6659 0.88 3487 16044 2 1154.666948 578.3402 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.37 3277.3 - 742988 - - - 0.8877 - 2.019 0.436 - 276.3 1 2 0 0.001 11 0 0 0 7.58E+07 8.65E+07 - - - 4.1617 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.16051.16051.2 0.0174 18-Aug R.VPFLVAETPR.A sp|Q13131|AAPK1_HUMAN 1 1127.6339 8.28 3492 16051 2 1127.636539 564.8242 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4 5.97 3278.2 - 441245 - - - 2.3447 - 1.654 0.309 - 178.1 1 2 0 0.0026 10 0 0 0 1.68E+07 2.03E+06 - - - 2.727 0.8972 230117_WJC_METTL3_WT_vs_EV_F01.16055.16055.2 0.102 14-Jul H.SLIPSYIR[166.11].D "sp|Q5JT25|RAB41_HUMAN,sp|P20340|RAB6A_HUMAN,sp|Q9NRW1|RAB6B_HUMAN,tr|J3KR73|J3KR73_HUMAN,tr|C9JU14|C9JU14_HUMAN" 5 957.5523 1.16 3494 16055 2 957.554074 479.7834 Ras-related protein Rab-41 OS=Homo sapiens OX=9606 GN=RAB41 PE=1 SV=2 8.46 3278.8 - 6.95E+06 - - - 1.8662 - 1.43 0.266 - 116.7 1 1 0 0.0018 8 0 0 0 1.72E+08 1.48E+08 - - - 2.0838 1 230117_WJC_METTL3_WT_vs_EV_F01.16058.16058.2 3.43E-05 16-Aug K.VIVPNMEFR.A sp|P55060|XPO2_HUMAN 1 1103.5798 1.28 3496 16058 2 1103.582871 552.7972 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.97 3279.1 - 314591 - - - 2.8272 - 1.66 0.553 - 210.1 1 2 0 0.0031 9 0 0 0 1.90E+08 1.48E+08 - - - 4.5907 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.16059.16059.2 0.000203 18-Aug R.GYFEYIEENK.Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1290.5768 1.51 3497 16059 2 1290.575976 646.2957 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3279.2 - 268949 - - - -0.664 - 1.797 0.449 - 120.1 1 2 0 -0.0009 10 0 0 0 1.40E+07 9.24E+06 - - - 3.9931 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.16064.16064.2 0.00823 18-Oct R.TVPLLLAESK[136.11].F sp|Q709C8|VP13C_HUMAN 1 1077.6525 1.11 3499 16064 2 1077.654361 539.8335 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 5.66 3279.9 - 311179 - - - 1.7167 - 1.697 0.365 - 287 1 2 0 0.0018 10 0 0 0 1.63E+07 1.48E+07 - - - 3.2125 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.16067.16067.2 0.397 14-Jul K.LLFVPC[160.03]SR.V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 990.5321 0.88 3501 16067 2 990.532877 496.2733 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.25 3280.1 - 2.11E+06 - - - 0.8127 - 1.519 0.157 - 174.7 1 2 0 0.0008 8 0 0 0 5.38E+07 6.09E+07 - - - 1.4612 0.8779 230117_WJC_METTL3_WT_vs_EV_F01.16076.16076.2 0.471 12-Sep A.IIAELLR.L "sp|Q12768|WASC5_HUMAN,sp|P16444|DPEP1_HUMAN,sp|Q9Y4D8|HECD4_HUMAN,sp|Q7L2E3|DHX30_HUMAN,sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HJX8|A0A804HJX8_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A494C150|A0A494C150_HUMAN,tr|A0A804HJG8|A0A804HJG8_HUMAN,tr|F8VWT9|F8VWT9_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|H7BXY3|H7BXY3_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|J3KPF0|J3KPF0_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 24 826.5276 1.03 3506 16076 2 826.527284 414.2711 WASH complex subunit 5 OS=Homo sapiens OX=9606 GN=WASHC5 PE=1 SV=1 6 3281.3 - 2.69E+06 - - - -0.4295 - 1.804 0.211 - 259.6 1 1 0 -0.0004 7 0 0 0 3.60E+08 3.51E+08 - - - 2.4688 1 230117_WJC_METTL3_WT_vs_EV_F01.16079.16079.2 1.16E-05 18-Nov K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 8.06 3509 16079 2 1149.580928 575.7982 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3281.7 - 156050 - - - -0.8099 - 2.102 0.478 - 312.9 1 2 0 -0.0009 10 0 0 0 1.27E+09 1.58E+08 - - - 4.6448 1 230117_WJC_METTL3_WT_vs_EV_F01.16100.16100.2 0.0061 18-Nov K.FAEAFEAIPR[166.11].A sp|P50990|TCPQ_HUMAN 1 1159.5901 7.92 3520 16100 2 1159.590888 580.8023 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3284.4 - 339353 - - - 0.6545 - 2.357 0.515 - 421.9 1 2 0 0.0008 10 0 0 0 1.27E+09 1.60E+08 - - - 5.2378 0.9833 230117_WJC_METTL3_WT_vs_EV_F01.16102.16102.2 0.781 14-Sep R.TAYLLYYR[166.11].R sp|Q14694|UBP10_HUMAN 1 1071.5629 1 3522 16102 2 1071.564019 536.7887 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.16 3284.5 - 1.04E+06 - - - 1.0891 - 1.2 0.073 - 246.7 1 2 0 0.0012 8 0 0 0 4.88E+07 4.89E+07 - - - 0.1297 0.9958 230117_WJC_METTL3_WT_vs_EV_F01.16109.16109.2 0.184 24-Sep K.LGPGAGAGFGVLR.R "sp|Q9BUL5|PHF23_HUMAN,tr|I3L1N0|I3L1N0_HUMAN,tr|I3L410|I3L410_HUMAN,tr|I3L4Q4|I3L4Q4_HUMAN" 4 1170.6509 8.89 3525 16109 2 1170.653164 586.3327 PHD finger protein 23 OS=Homo sapiens OX=9606 GN=PHF23 PE=1 SV=1 9.75 3285.5 - 455443 - - - 1.8981 - 1.473 0.153 - 105 1 2 0 0.0022 13 0 0 0 2.58E+07 2.90E+06 - - - 1.1644 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.16114.16114.2 0.0149 16-Aug K.IYPVGYFTK.E "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 1086.575 17.2 3527 16114 2 1086.577081 544.2948 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.5 3286.1 - 1.17E+06 - - - 1.9308 - 1.389 0.301 - 209.8 1 2 0 0.0021 9 0 0 0 5.06E+07 2.94E+06 - - - 2.2141 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.16115.16115.2 0.218 12-May R.EEYLLLR[166.11].L "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 944.5207 1.83 3528 16115 2 944.521191 473.2676 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.53 3286.2 - 932664 - - - 0.5696 - 1.255 0.293 - 106.2 1 2 0 0.0005 7 0 0 0 7.20E+07 3.93E+07 - - - 1.9246 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.16128.16128.2 0.000206 14-Aug K.FC[160.03]ELLIGR.G "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1006.527 999 3537 16128 2 1006.52986 504.2708 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.99 3287.6 - 876982 - - - 2.8544 - 1.803 0.459 - 194.3 1 2 0 0.0029 8 0 0 0 2.23E+07 0.00E+00 - - - 4.208 0.999 230117_WJC_METTL3_WT_vs_EV_F01.16132.16132.2 0.0747 12-Aug K.YGAFLLR[166.11].R "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 848.4784 1.11 3539 16132 2 848.480037 425.2465 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.75 3288.1 - 908666 - - - 1.9364 - 1.79 0.213 - 233.5 1 2 0 0.0016 7 0 0 0 6.27E+07 5.66E+07 - - - 2.4585 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.16144.16144.2 0.00507 20-Nov K.LLLIGDSGVGK.T "sp|P61006|RAB8A_HUMAN,sp|P51153|RAB13_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P59190|RAB15_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YL94|H0YL94_HUMAN,tr|A0A2R8YDI9|A0A2R8YDI9_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|G3V196|G3V196_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H0YLJ8|H0YLJ8_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN,tr|F5H157|F5H157_HUMAN" 19 1070.6336 1.45 3549 16144 2 1070.639076 536.3241 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.84 3289.5 - 2.19E+06 - - - 5.1521 - 2.33 0.396 - 377.2 1 2 0 0.0055 11 0 0 0 6.72E+08 4.62E+08 - - - 4.2524 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.16145.16145.2 0.434 14-Jul K.LFIGNLPR[166.11].E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 938.5577 2.15 3550 16145 2 938.559441 470.2861 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3289.6 - 1.89E+06 - - - 1.8475 - 1.462 0.185 - 163.4 1 2 0 0.0017 8 0 0 0 4.57E+09 2.13E+09 - - - 1.5523 0.997 230117_WJC_METTL3_WT_vs_EV_F01.16146.16146.2 0.127 12-Jul K.MIFVGIK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 806.4724 2.07 3551 16146 2 806.474767 404.2435 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 8.5 3289.6 - 1.76E+06 - - - 2.8953 - 1.37 0.244 - 228.4 1 2 0 0.0023 7 0 0 0 6.27E+07 3.04E+07 - - - 1.8399 0.9951 230117_WJC_METTL3_WT_vs_EV_F01.16151.16151.2 0.0404 14-Jul R.VLSIWEER[166.11].S "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1040.553 6.32 3554 16151 2 1040.553684 521.2838 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.53 3290.4 - 1.64E+06 - - - 0.6429 - 1.542 0.098 - 159.8 1 2 0 0.0007 8 0 0 0 3.30E+08 5.22E+07 - - - 1.0708 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.16161.16161.2 0.0413 16-Aug K.VIVPNMEFR[166.11].A sp|P55060|XPO2_HUMAN 1 1113.588 1.28 3559 16161 2 1113.590047 557.8013 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.97 3291.6 - 822925 - - - 1.8193 - 1.494 0.27 - 199.1 1 2 0 0.002 9 0 0 0 1.90E+08 1.48E+08 - - - 2.196 0.9954 230117_WJC_METTL3_WT_vs_EV_F01.16166.16166.2 0.22 16-Jul K.VYEAVELLK.S sp|Q8TEQ6|GEMI5_HUMAN 1 1062.5961 0.42 3561 16166 2 1062.598671 532.3053 Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3 4.53 3292.2 - 1.20E+06 - - - 2.4083 - 1.16 0.241 - 119.9 1 2 0 0.0026 9 0 0 0 3.05E+07 7.28E+07 - - - 1.2496 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.16167.16167.3 0.0323 14/36 K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 13.33 3562 16167 3 1149.583479 384.2012 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3292.3 - 638643 - - - 1.4092 - 1.823 0.409 - 326.1 1 2 0 0.0016 10 0 0 0 2.24E+07 1.68E+06 - - - 4.8532 0.958 230117_WJC_METTL3_WT_vs_EV_F01.16172.16172.2 4.01 14-May R.LISLPLSR[166.11].L "sp|Q9NRG0|CHRC1_HUMAN,tr|E5RGS9|E5RGS9_HUMAN" 2 907.573 1.76 3565 16172 2 907.573965 454.7938 Chromatin accessibility complex protein 1 OS=Homo sapiens OX=9606 GN=CHRAC1 PE=1 SV=1 9.75 3292.9 - 915202 - - - 1.0379 - 1.056 0.044 - 65 1 2 0 0.0009 8 0 0 0 1.40E+08 7.98E+07 - - - -0.47 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.16177.16177.2 0.0611 14-Aug R.LEEIPLIK.S sp|Q14152|EIF3A_HUMAN 1 953.5797 0.9 3567 16177 2 953.578103 477.7971 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 3293.5 - 1.94E+06 - - - -1.7104 - 1.651 0.247 - 131.5 1 2 0 -0.0016 8 0 0 0 1.11E+08 1.24E+08 - - - 2.377 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.16178.16178.2 0.298 16-Oct K.LTLLQVASR.Q sp|O95239|KIF4A_HUMAN 1 999.6077 2.14 3568 16178 2 999.609119 500.8111 Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3 9.75 3293.6 - 1.64E+06 - - - 1.4396 - 1.889 0.228 - 286.3 1 2 0 0.0014 9 0 0 0 4.86E+07 2.27E+07 - - - 2.5647 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.16184.16184.2 0.0888 12-Jul K.FGDFVLK[136.11].S "sp|P11172|UMPS_HUMAN,tr|F2Z303|F2Z303_HUMAN,tr|F2Z3P2|F2Z3P2_HUMAN,tr|F8WDG4|F8WDG4_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 5 832.4574 2.45 3572 16184 2 832.457965 417.236 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 5.84 3294.4 - 4.85E+06 - - - 0.6307 - 1.291 0.333 - 104.2 1 2 0 0.0005 7 0 0 0 1.04E+08 4.22E+07 - - - 2.3097 0.9892 230117_WJC_METTL3_WT_vs_EV_F01.16188.16188.2 0.0223 20-Jul M.PMFIVNTNVPR.A sp|P14174|MIF_HUMAN 1 1286.6805 5.4 3576 16188 2 1286.688117 644.3475 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 10.18 3294.9 - 102123 - - - 5.8989 - 1.537 0.32 - 159.2 1 2 0 0.0076 11 0 0 0 4.12E+06 7.62E+05 - - - 2.5649 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.16193.16193.2 0.816 12-Aug K.IIAALFK[136.11].A "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 782.5146 1.6 3579 16193 2 782.515773 392.2646 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3295.5 - 1.37E+06 - - - 1.5489 - 1.553 0.159 - 161.2 1 2 0 0.0012 7 0 0 0 4.69E+07 2.93E+07 - - - 1.6098 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.16206.16206.2 0.0262 14-Aug R.GFVLYPVK.Y sp|P62487|RPB7_HUMAN 1 921.5324 0.01 3588 16206 2 921.533054 461.7735 DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1 8.59 3297.1 - 708451 - - - 0.7205 - 1.295 0.371 - 163.9 1 2 0 0.0007 8 0 0 0 2.80E+07 2.26E+09 - - - 2.5607 0.9958 230117_WJC_METTL3_WT_vs_EV_F01.16212.16212.2 0.000889 18-Jul K.ILVEEMAPLK.G "sp|Q16670|ZSC26_HUMAN,tr|A0A087WXM4|A0A087WXM4_HUMAN,tr|A0A024RCN4|A0A024RCN4_HUMAN,tr|A0A087X2F1|A0A087X2F1_HUMAN" 4 1141.6417 999 3592 16212 2 1141.648054 571.8281 Zinc finger and SCAN domain-containing protein 26 OS=Homo sapiens OX=9606 GN=ZSCAN26 PE=1 SV=2 4.53 3297.9 - 241429 - - - 5.5814 - 1.633 0.426 - 66.8 1 2 0 0.0064 10 0 0 0 7.09E+06 0.00E+00 - - - 3.5543 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.16213.16213.2 0.0443 18-Sep K.AMTILLEEAK.A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1117.6053 2.24 3593 16213 2 1117.606547 559.8099 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3298 - 364902 - - - 1.1185 - 1.908 0.338 - 184.2 1 2 0 0.0013 10 0 0 0 5.76E+07 2.58E+07 - - - 3.3404 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.16214.16214.2 0.0102 18-Aug R.ILIAKPIMFR.G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1200.7417 1.03 3594 16214 2 1200.742768 601.3781 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3298.1 - 265031 - - - 0.9136 - 1.753 0.263 - 181.2 1 2 0 0.0011 10 0 0 0 4.47E+06 4.35E+06 - - - 2.55 0.9792 230117_WJC_METTL3_WT_vs_EV_F01.16215.16215.2 0.97 18-May R.ILIAK[136.11]PIMFR[166.11].G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1218.7641 1 3595 16215 2 1218.765873 610.3893 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3298.3 - 214062 - - - 1.4211 - 1.158 0.1 - 59.6 3 2 0 0.0017 10 0 0 0 4.47E+06 4.45E+06 - - - -0.0246 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.16221.16221.2 0.0117 18-Aug K.AMTILLEEAK[136.11].A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1125.6195 2.25 3599 16221 2 1125.619215 563.817 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3298.9 - 353006 - - - -0.2505 - 1.664 0.319 - 130.9 1 2 0 -0.0003 10 0 0 0 5.71E+07 2.54E+07 - - - 2.8184 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.16224.16224.2 1.25 12-Aug R.LSAIFLR.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 818.5014 1.51 3600 16224 2 818.503632 410.258 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3299.3 - 1.18E+06 - - - 2.6976 - 1.694 0.093 - 208.3 1 2 0 0.0022 7 0 0 0 6.49E+07 4.30E+07 - - - 1.3973 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.16229.16229.3 0.000196 Oct-36 R.ILIAK[136.11]PIMFR[166.11].G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1218.7641 4.07 3603 16229 3 1218.765328 407.262 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3299.9 - 2.66E+06 - - - 0.9739 - 1.808 0.442 - 86.9 1 2 0 0.0012 10 0 0 0 2.01E+08 4.93E+07 - - - 5.1971 0.8537 230117_WJC_METTL3_WT_vs_EV_F01.16239.16239.2 0.662 16-Nov V.IQQQYQANR[166.11].A "sp|Q8IZT6|ASPM_HUMAN,tr|A0A7P0Z491|A0A7P0Z491_HUMAN,tr|A0A7P0Z4R7|A0A7P0Z4R7_HUMAN" 3 1157.5817 0.59 3609 16239 2 1157.58272 579.7981 Abnormal spindle-like microcephaly-associated protein OS=Homo sapiens OX=9606 GN=ASPM PE=1 SV=2 8.75 3301.1 - 639612 - - - 0.8898 - 1.576 0.181 - 398.3 1 1 0 0.001 9 0 0 0 3.34E+07 5.71E+07 - - - 1.6936 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.16243.16243.2 0.00315 12-Jun R.EYFYGFR.G "sp|Q92989|CLP1_HUMAN,tr|E9PL17|E9PL17_HUMAN" 2 980.4392 5.1 3613 16243 2 980.441265 491.2269 Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1 6.1 3301.5 - 159207 - - - 2.0878 - 1.253 0.333 - 101.3 1 2 0 0.002 7 0 0 0 6.01E+06 1.18E+06 - - - 2.2145 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.16245.16245.2 0.0945 14-Jul K.LFIGNLPR.E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 928.5494 2.14 3614 16245 2 928.551052 465.282 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3301.8 - 1.18E+08 - - - 1.7393 - 1.458 0.34 - 212.7 1 2 0 0.0016 8 0 0 0 4.57E+09 2.13E+09 - - - 2.6889 0.9956 230117_WJC_METTL3_WT_vs_EV_F01.16248.16248.2 1.81 12-Aug R.LSAIFLR[166.11].L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 828.5097 1.57 3615 16248 2 828.509894 415.2621 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3302.2 - 1.14E+06 - - - 0.2414 - 1.681 0.08 - 152.2 1 2 0 0.0002 7 0 0 0 6.49E+07 4.13E+07 - - - 1.2775 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.16255.16255.2 0.00761 16-Sep K.VVDVLDSIK[136.11].T sp|P00918|CAH2_HUMAN 1 994.579 0.81 3620 16255 2 994.580957 498.2968 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.21 3302.9 - 455446 - - - 1.9556 - 1.921 0.233 - 221.3 1 2 0 0.0019 9 0 0 0 2.95E+07 3.64E+07 - - - 2.65 0.999 230117_WJC_METTL3_WT_vs_EV_F01.16261.16261.2 0.0719 20-Aug K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.14 3625 16261 2 1235.76213 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3303.6 - 2.09E+06 - - - 1.5958 - 1.791 0.246 - 202.4 1 2 0 0.002 11 0 0 0 6.43E+08 5.66E+08 - - - 2.4339 0.9859 230117_WJC_METTL3_WT_vs_EV_F01.16263.16263.2 3.2 12-Jul R.NLVLLVR[166.11].E sp|Q9H2W6|RM46_HUMAN 1 835.5519 1.08 3626 16263 2 835.553496 418.7832 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 9.75 3303.9 - 2.97E+06 - - - 1.9185 - 1.416 0.02 - 237.4 1 2 0 0.0016 7 0 0 0 6.50E+07 6.02E+07 - - - 0.2904 0.9962 230117_WJC_METTL3_WT_vs_EV_F01.16264.16264.2 2.67 12-Aug K.ILPDILK.K "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 810.5215 1.17 3627 16264 2 810.523252 406.268 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 3304 - 2.03E+06 - - - 2.1727 - 1.508 0.133 - 157.6 1 2 0 0.0018 7 0 0 0 1.14E+08 9.76E+07 - - - 1.3244 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.16268.16268.2 0.00309 18-Oct K.GFLAGYVVAK.L sp|L0R6Q1|S35U4_HUMAN 1 1023.5753 4.55 3631 16268 2 1023.577645 512.7949 SLC35A4 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=SLC35A4 PE=3 SV=1 8.59 3304.5 - 936444 - - - 2.2744 - 1.771 0.342 - 194.1 1 2 0 0.0023 10 0 0 0 3.08E+07 6.77E+06 - - - 3.1616 0.984 230117_WJC_METTL3_WT_vs_EV_F01.16269.16269.2 0.000941 20-Aug K.C[160.03]ILVASPGFVR.E sp|Q9BRX2|PELO_HUMAN 1 1217.6591 4.04 3632 16269 2 1217.668378 609.8368 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 8.25 3304.6 - 274226 - - - 7.6491 - 1.607 0.417 - 146.4 1 2 0 0.0093 11 0 0 0 2.20E+07 5.45E+06 - - - 3.4013 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.16271.16271.2 0.0621 20-Aug K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.14 3633 16271 2 1245.770468 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3304.8 - 1.43E+06 - - - 1.6375 - 1.761 0.327 - 178 1 2 0 0.002 11 0 0 0 6.46E+08 5.69E+08 - - - 2.9864 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.16276.16276.2 0.0227 14-Sep M.VLLTMIAR.V sp|O75396|SC22B_HUMAN 1 915.5576 0.68 3636 16276 2 915.561034 458.7861 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 9.72 3305.4 - 3.11E+06 - - - 3.7955 - 1.68 0.316 - 316.9 1 2 0 0.0035 8 0 0 0 9.64E+07 1.42E+08 - - - 2.9385 1 230117_WJC_METTL3_WT_vs_EV_F01.16277.16277.2 4.47E-06 14/18 K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 351.42 3637 16277 2 1146.630166 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3305.5 - 2.50E+06 - - - 1.4748 - 2.374 0.502 - 560.3 1 2 0 0.0017 10 0 0 0 7.38E+09 2.10E+07 - - - 5.1615 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.16278.16278.2 0.0234 16-Sep K.VVDVLDSIK.T sp|P00918|CAH2_HUMAN 1 986.5648 0.83 3638 16278 2 986.567139 494.2897 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.21 3305.6 - 1.38E+06 - - - 2.3587 - 1.471 0.273 - 203.9 1 2 0 0.0023 9 0 0 0 2.98E+07 3.62E+07 - - - 2.1732 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.16279.16279.2 0.0088 18-Nov K.LLADELISPK[136.11].D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1105.6474 1.1 3639 16279 2 1105.648868 553.831 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3305.7 - 1.24E+06 - - - 1.3042 - 2.032 0.359 - 236.2 1 2 0 0.0014 10 0 0 0 8.84E+07 8.03E+07 - - - 3.6712 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.16282.16282.2 0.597 12-Jul R.LIFDNLK.K "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P54707|AT12A_HUMAN,sp|P20648|ATP4A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 11 861.496 1.02 3641 16282 2 861.498138 431.7553 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.84 3306.1 - 825242 - - - 2.4771 - 1.331 0.261 - 114.7 1 2 0 0.0021 7 0 0 0 7.78E+07 7.66E+07 - - - 1.8741 0.9236 230117_WJC_METTL3_WT_vs_EV_F01.16287.16287.2 3.71 14-Jun R.LISELFQK.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN" 4 976.5593 2.9 3645 16287 2 976.558826 489.2869 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 6 3306.6 - 1.27E+06 - - - -0.5192 - 1.185 0.058 - 54.5 9 2 0 -0.0005 8 0 0 0 9.00E+07 3.10E+07 - - - -0.4451 1 230117_WJC_METTL3_WT_vs_EV_F01.16289.16289.2 8.54E-07 20-Dec K.NSLESYAFNMK.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1302.5914 95.07 3647 16289 2 1302.593223 652.303 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6 3306.9 - 524431 - - - 1.3703 - 2.452 0.595 - 747.4 1 2 0 0.0018 11 0 0 0 1.64E+07 1.72E+05 - - - 5.8614 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.16292.16292.2 0.586 12-Jul K.ILPDILK[136.11].K "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 818.5357 2.36 3648 16292 2 818.537348 410.2751 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 3307.3 - 971826 - - - 2.0243 - 1.4 0.146 - 102.8 1 2 0 0.0017 7 0 0 0 1.09E+08 4.63E+07 - - - 1.185 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.16293.16293.2 0.111 16-Jul K.AFIGFEGVK.G sp|P15924|DESP_HUMAN 1 966.5175 1.97 3649 16293 2 966.518608 484.266 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.05 3307.3 - 182506 - - - 1.1795 - 1.373 0.169 - 111.5 1 2 0 0.0011 9 0 0 0 6.40E+07 3.25E+07 - - - 1.206 0.984 230117_WJC_METTL3_WT_vs_EV_F01.16294.16294.2 1.06 12-Jun K.AFIVELR[166.11].Q sp|O43318|M3K7_HUMAN 1 856.5046 0.86 3650 16294 2 856.505272 429.2596 Mitogen-activated protein kinase kinase kinase 7 OS=Homo sapiens OX=9606 GN=MAP3K7 PE=1 SV=1 6.05 3307.4 - 518343 - - - 0.7741 - 1.297 0.045 - 133.5 1 2 0 0.0007 7 0 0 0 9.04E+06 1.06E+07 - - - 0.1972 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.16297.16297.2 0.000274 18-Dec K.LLADELISPK.D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1097.6332 1.06 3652 16297 2 1097.637686 549.8239 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3307.7 - 1.03E+06 - - - 4.0633 - 2.428 0.31 - 374.8 1 2 0 0.0045 10 0 0 0 9.02E+07 8.52E+07 - - - 3.8053 1 230117_WJC_METTL3_WT_vs_EV_F01.16304.16304.2 0.00407 16-Sep R.FDDPLLGPR[166.11].R "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 8 1038.5374 0.86 3657 16304 2 1038.538896 520.276 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.21 3308.4 - 589474 - - - 1.4742 - 2.187 0.478 - 260.8 1 2 0 0.0015 9 0 0 0 8.57E+07 9.94E+07 - - - 4.8349 0.997 230117_WJC_METTL3_WT_vs_EV_F01.16309.16309.2 0.00129 16-Jul R.IVLNGIDLK.A sp|O15294|OGT1_HUMAN 1 983.6015 2.1 3660 16309 2 983.603125 492.808 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 5.84 3308.9 - 969907 - - - 1.6196 - 1.504 0.158 - 85 1 2 0 0.0016 9 0 0 0 3.67E+07 1.75E+07 - - - 1.3882 0.997 230117_WJC_METTL3_WT_vs_EV_F01.16310.16310.2 0.0781 16-Jul R.IVLNGIDLK[136.11].A sp|O15294|OGT1_HUMAN 1 991.6157 2.1 3661 16310 2 991.616098 496.8151 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 5.84 3309 - 435132 - - - 0.3691 - 1.393 0.208 - 104.4 1 2 0 0.0004 9 0 0 0 3.67E+07 1.75E+07 - - - 1.5361 0.9656 230117_WJC_METTL3_WT_vs_EV_F01.16312.16312.2 0.519 16-Aug R.LLGLEEQLR[166.11].A "sp|P28290|ITPI2_HUMAN,tr|E9PHV5|E9PHV5_HUMAN,tr|E7EUL7|E7EUL7_HUMAN" 3 1079.6214 2.7 3663 16312 2 1079.618856 540.818 Protein ITPRID2 OS=Homo sapiens OX=9606 GN=ITPRID2 PE=1 SV=3 4.53 3309.2 - 118791 - - - -2.3832 - 1.568 0.078 - 126.6 1 2 0 -0.0026 9 0 0 0 1.49E+07 5.50E+06 - - - 0.9176 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.16315.16315.2 0.421 14-Sep R.LMGLEALK.S "sp|P48643|TCPE_HUMAN,tr|D6RIZ7|D6RIZ7_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0Y914|H0Y914_HUMAN" 4 873.4994 5.95 3664 16315 2 873.501816 437.757 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 3309.6 - 929977 - - - 2.7945 - 1.539 0.166 - 166 1 2 0 0.0024 8 0 0 0 3.51E+09 5.91E+08 - - - 1.5666 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.16316.16316.2 0.0059 16-Aug R.WLNYGGVIK.N "sp|P49642|PRI1_HUMAN,tr|F8VSB2|F8VSB2_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN" 3 1048.5706 0.75 3665 16316 2 1048.573221 525.2926 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 8.59 3309.8 - 455486 - - - 2.532 - 1.697 0.222 - 160.9 1 2 0 0.0027 9 0 0 0 6.46E+06 8.66E+06 - - - 2.2099 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.16323.16323.2 0.243 14-Aug R.LLNTFLER.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 8 1004.5655 1.41 3667 16323 2 1004.565806 503.29 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3310.8 - 509002 - - - 0.3235 - 1.648 0.213 - 139.8 1 2 0 0.0003 8 0 0 0 1.95E+08 1.38E+08 - - - 2.1208 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.16327.16327.2 0.00174 20-Nov K.LLDSITVPVAR.A sp|O00203|AP3B1_HUMAN 1 1182.6972 1.47 3669 16327 2 1182.698105 592.3559 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3311.2 - 851305 - - - 0.7458 - 2.17 0.434 - 337.8 1 2 0 0.0009 11 0 0 0 3.44E+07 2.34E+07 - - - 4.3421 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.16334.16334.2 0.031 12-Jul R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 49.1 3674 16334 2 806.39273 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 3312.1 - 1.84E+06 - - - 0.5742 - 1.515 0.272 - 190.5 1 2 0 0.0005 7 0 0 0 6.39E+07 1.30E+06 - - - 2.3661 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.16335.16335.2 0.0328 18-Sep R.LTPLQLEIQR.V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1209.7081 1.18 3675 16335 2 1209.709256 605.8613 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 3312.2 - 2.46E+06 - - - 0.9374 - 1.572 0.27 - 324.9 1 2 0 0.0011 10 0 0 0 5.95E+07 5.05E+07 - - - 2.2975 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.16336.16336.2 0.00406 18-Sep R.LTPLQLEIQR[166.11].V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1219.7164 1.18 3676 16336 2 1219.718775 610.8655 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 3312.3 - 2.31E+06 - - - 1.9537 - 1.683 0.352 - 346.9 1 2 0 0.0024 10 0 0 0 5.95E+07 5.05E+07 - - - 3.0932 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.16337.16337.2 0.425 16-Aug R.LLGLEEQLR.A "sp|P28290|ITPI2_HUMAN,tr|E9PHV5|E9PHV5_HUMAN,tr|E7EUL7|E7EUL7_HUMAN" 3 1069.6132 2.7 3677 16337 2 1069.615023 535.8139 Protein ITPRID2 OS=Homo sapiens OX=9606 GN=ITPRID2 PE=1 SV=3 4.53 3312.4 - 1.50E+06 - - - 1.7427 - 1.566 0.203 - 153 1 2 0 0.0019 9 0 0 0 1.49E+07 5.50E+06 - - - 1.8374 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.16339.16339.2 0.000128 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 349.91 3679 16339 2 1154.643015 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3312.6 - 1.07E+06 - - - 0.2945 - 1.932 0.405 - 261.3 1 2 0 0.0003 10 0 0 0 7.35E+09 2.10E+07 - - - 3.8705 1 230117_WJC_METTL3_WT_vs_EV_F01.16344.16344.2 0.0116 20-Dec K.LLDSITVPVAR[166.11].A sp|O00203|AP3B1_HUMAN 1 1192.7055 1.47 3682 16344 2 1192.7086 597.36 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3313.3 - 694629 - - - 2.605 - 2.386 0.469 - 428.6 1 2 0 0.0031 11 0 0 0 3.44E+07 2.34E+07 - - - 4.8566 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.16346.16346.2 0.126 12-Jul K.MFEFYER.V "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 13 1020.4375 2.23 3684 16346 2 1020.439446 511.226 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3313.5 - 925403 - - - 1.9041 - 1.449 0.243 - 186.5 1 2 0 0.0019 7 0 0 0 3.14E+07 1.41E+07 - - - 2.0103 1 230117_WJC_METTL3_WT_vs_EV_F01.16352.16352.2 0.000187 14/22 K.LGALTAEEIALK.M sp|Q13601|KRR1_HUMAN 1 1227.7075 1.24 3687 16352 2 1227.707813 614.861 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3314.2 - 1.30E+06 - - - 0.2924 - 2.665 0.442 - 699.6 1 2 0 0.0004 12 0 0 0 2.35E+08 1.90E+08 - - - 4.8846 0.997 230117_WJC_METTL3_WT_vs_EV_F01.16360.16360.2 10.4 12-Jul K.DVLLPLK.S sp|Q9Y385|UB2J1_HUMAN 1 796.5058 1.16 3693 16360 2 796.506899 399.2602 Ubiquitin-conjugating enzyme E2 J1 OS=Homo sapiens OX=9606 GN=UBE2J1 PE=1 SV=2 5.84 3315.1 - 215949 - - - 1.3283 - 1.502 0.142 - 204.2 1 2 0 0.0011 7 0 0 0 1.30E+07 1.12E+07 - - - 1.3784 1 230117_WJC_METTL3_WT_vs_EV_F01.16365.16365.2 3.34E-05 22-Dec K.LGALTAEEIALK[136.11].M sp|Q13601|KRR1_HUMAN 1 1235.7217 1.24 3696 16365 2 1235.720535 618.8681 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3315.8 - 6.48E+06 - - - -0.9055 - 2.476 0.43 - 455.3 1 2 0 -0.0011 12 0 0 0 2.34E+08 1.90E+08 - - - 4.6022 0.9921 230117_WJC_METTL3_WT_vs_EV_F01.16373.16373.2 0.0073 18-Jul K.IPVSGPFLVK.T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1055.6379 1.29 3702 16373 2 1055.635083 528.8262 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3316.8 - 720421 - - - -2.6856 - 1.536 0.308 - 73.8 2 2 0 -0.0028 10 0 0 0 1.96E+08 1.52E+08 - - - 2.3785 0.9407 230117_WJC_METTL3_WT_vs_EV_F01.16374.16374.2 0.0189 22-Sep R.GLLQDDAHPTLV.T "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1277.6616 - 3703 16374 2 1277.663432 639.8381 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3317 - 674993 - - - 1.4605 - 1.746 0.289 - 118.4 1 1 0 0.0019 12 0 0 0 - - - - - 2.6414 0.9936 230117_WJC_METTL3_WT_vs_EV_F01.16375.16375.2 0.000165 22-Oct R.VFASELNAGIIK[136.11].T "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1268.722 1.49 3704 16375 2 1268.729383 635.3683 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.97 3317.1 - 428022 - - - 5.8287 - 1.945 0.321 - 232.1 1 2 0 0.0074 12 0 0 0 2.66E+07 1.78E+07 - - - 3.16 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.16380.16380.2 0.0197 14-Sep K.FYSFALDK.T sp|Q96T58|MINT_HUMAN 1 989.4858 1.41 3706 16380 2 989.483986 495.7502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.83 3317.7 - 865724 - - - -1.8676 - 1.701 0.276 - 236.3 1 2 0 -0.0018 8 0 0 0 3.25E+07 2.31E+07 - - - 2.6811 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.16383.16383.2 0.00374 18-Nov K.LGLTEDQFIR.T "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1190.6295 2.57 3709 16383 2 1190.629747 596.322 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.37 3318 - 628007 - - - 0.1755 - 1.59 0.363 - 287.6 1 2 0 0.0002 10 0 0 0 2.18E+07 8.47E+06 - - - 3.0165 0.9756 230117_WJC_METTL3_WT_vs_EV_F01.16386.16386.2 0.59 12-May K.LFQLYPR.N sp|Q8IXM3|RM41_HUMAN 1 935.5229 1.47 3710 16386 2 935.527191 468.7687 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 8.75 3318.4 - 4.19E+06 - - - 4.5996 - 1.299 0.175 - 70.9 2 2 0 0.0043 7 0 0 0 2.07E+08 1.41E+08 - - - 1.0266 0.9087 230117_WJC_METTL3_WT_vs_EV_F01.16387.16387.2 0.0649 18-Aug F.LLVGTQIDLR.D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1126.671 1.49 3711 16387 2 1126.670232 564.3428 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.84 3318.5 - 560243 - - - -0.6896 - 1.886 0.303 - 191.3 1 1 0 -0.0008 10 0 0 0 2.44E+07 1.64E+07 - - - 3.0497 1 230117_WJC_METTL3_WT_vs_EV_F01.16390.16390.2 0.00538 14/22 K.VLVALASEELAK[136.11].G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1249.7373 1.66 3712 16390 2 1249.737464 625.8759 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.53 3318.9 - 1.51E+06 - - - 0.128 - 2.672 0.428 - 663.6 1 2 0 0.0002 12 0 0 0 6.94E+07 4.19E+07 - - - 4.7881 0.9876 230117_WJC_METTL3_WT_vs_EV_F01.16392.16392.2 0.366 14-Jun R.EPLLTLVK.E sp|Q13200|PSMD2_HUMAN 1 911.5692 1.87 3713 16392 2 911.567916 456.7919 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 6.1 3319.1 - 2.78E+06 - - - -1.3746 - 1.424 0.151 - 126.6 1 2 0 -0.0013 8 0 0 0 2.26E+08 1.21E+08 - - - 1.2219 0.9949 230117_WJC_METTL3_WT_vs_EV_F01.16393.16393.2 0.0451 18-Sep K.IPVSGPFLVK[136.11].T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1063.6521 1.29 3714 16393 2 1063.651078 532.8333 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3319.3 - 1.31E+06 - - - -0.9778 - 1.395 0.242 - 181.9 1 2 0 -0.001 10 0 0 0 1.96E+08 1.52E+08 - - - 1.7573 0.9763 230117_WJC_METTL3_WT_vs_EV_F01.16404.16404.2 0.247 12-Jun K.LMVIFSK.V "sp|Q9BRK5|CAB45_HUMAN,tr|A0A5F9UJX7|A0A5F9UJX7_HUMAN,tr|A0A5F9UP49|A0A5F9UP49_HUMAN,tr|G3V1E2|G3V1E2_HUMAN,tr|H0Y3T6|H0Y3T6_HUMAN" 5 836.483 0.27 3720 16404 2 836.482264 419.2488 45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1 8.75 3320.7 - 853792 - - - -0.8763 - 1.583 0.019 - 87.6 2 2 0 -0.0007 7 0 0 0 3.62E+07 1.36E+08 - - - 0.502 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.16407.16407.2 0.0562 20-Oct R.IDALLAVDPPR.A sp|P50219|MNX1_HUMAN 1 1178.6659 1.82 3722 16407 2 1178.666857 590.3402 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3321.1 - 435629 - - - 0.7924 - 2.08 0.304 - 308.8 1 2 0 0.0009 11 0 0 0 3.60E+07 1.98E+07 - - - 3.2673 1 230117_WJC_METTL3_WT_vs_EV_F01.16412.16412.2 2.43E-06 22-Nov K.VLVALASEELAK.G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1241.7231 1.66 3725 16412 2 1241.724012 621.8688 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.53 3321.7 - 5.64E+06 - - - 0.7312 - 2.33 0.535 - 350.1 1 2 0 0.0009 12 0 0 0 6.94E+07 4.19E+07 - - - 5.2178 0.9973 230117_WJC_METTL3_WT_vs_EV_F01.16414.16414.2 0.919 12-Jul K.LIIFDAR.Q "sp|Q13613|MTMR1_HUMAN,tr|Q8NEC6|Q8NEC6_HUMAN,tr|F8WA39|F8WA39_HUMAN,tr|H0YDX3|H0YDX3_HUMAN" 4 846.4963 4.48 3727 16414 2 846.497589 424.2554 Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4 5.84 3321.8 - 2.60E+06 - - - 1.4767 - 1.452 0.17 - 181.1 1 2 0 0.0013 7 0 0 0 1.13E+08 2.53E+07 - - - 1.4779 0.9856 230117_WJC_METTL3_WT_vs_EV_F01.16415.16415.2 7.39 16-Jul R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 3.6 3728 16415 2 960.610508 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3321.9 - 1.09E+06 - - - 0.6142 - 1.152 0.115 - 92.3 1 2 0 0.0006 9 0 0 0 8.91E+07 2.48E+07 - - - 0.2996 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.16416.16416.2 0.000205 20-Nov R.LLTGVEYVVGR[166.11].K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1214.6898 1.4 3729 16416 2 1214.691057 608.3522 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3322 - 1.07E+06 - - - 0.9994 - 2.265 0.434 - 316.2 1 2 0 0.0012 11 0 0 0 3.42E+07 2.44E+07 - - - 4.4579 1 230117_WJC_METTL3_WT_vs_EV_F01.16428.16428.2 5.50E-05 20-Nov R.LLTGVEYVVGR.K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1204.6816 1.61 3737 16428 2 1204.684781 603.3481 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3323.5 - 493609 - - - 2.6629 - 2.332 0.535 - 370.3 1 2 0 0.0032 11 0 0 0 3.95E+07 2.45E+07 - - - 5.2821 0.9973 230117_WJC_METTL3_WT_vs_EV_F01.16429.16429.2 0.247 16-Jul K.VILTSPLIR[166.11].D sp|Q96SI9|STRBP_HUMAN 1 1020.6571 1.92 3738 16429 2 1020.657458 511.3358 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 9.72 3323.6 - 877773 - - - 0.3635 - 1.392 0.224 - 103.9 1 2 0 0.0004 9 0 0 0 6.08E+07 3.16E+07 - - - 1.6522 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.16437.16437.2 0.0508 16-Oct R.IGLINDMVR[166.11].F sp|Q14152|EIF3A_HUMAN 1 1039.5724 1.04 3744 16437 2 1039.574471 520.7935 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.84 3324.6 - 1.70E+06 - - - 2.0201 - 1.609 0.217 - 259 1 2 0 0.0021 9 0 0 0 7.42E+07 7.14E+07 - - - 2.0191 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.16438.16438.2 0.0244 14-Jul R.LLNTFLER[166.11].L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 8 1014.5738 1.36 3745 16438 2 1014.574717 508.2942 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3324.7 - 8.24E+06 - - - 0.9521 - 1.394 0.308 - 128.9 1 2 0 0.001 8 0 0 0 1.87E+08 1.38E+08 - - - 2.3174 0.9659 230117_WJC_METTL3_WT_vs_EV_F01.16449.16449.2 9.17 12-May M.LPLSLLK.T "sp|Q9Y4Z0|LSM4_HUMAN,sp|Q969I6|S38A4_HUMAN,tr|F8VQY9|F8VQY9_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 5 782.5266 18.79 3752 16449 2 782.526125 392.2706 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 8.75 3326.1 - 900744 - - - -0.5763 - 1.393 0.004 - 58.7 1 2 0 -0.0005 7 0 0 0 2.10E+07 1.12E+06 - - - 0.1207 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.16450.16450.2 0.0522 12-Jul K.LMFEELR.N sp|Q9Y3I0|RTCB_HUMAN 1 936.4739 1.06 3753 16450 2 936.475148 469.2442 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.53 3326.1 - 2.33E+06 - - - 1.3444 - 1.41 0.283 - 178.3 1 2 0 0.0013 7 0 0 0 5.33E+07 5.04E+07 - - - 2.2195 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.16452.16452.2 0.0337 16-Aug R.IGFGSFVEK[136.11].T "sp|P05556|ITB1_HUMAN,sp|P18564|ITB6_HUMAN,tr|A0A7I2V2F9|A0A7I2V2F9_HUMAN,tr|A0A087WXP3|A0A087WXP3_HUMAN,tr|A0A7I2V5T3|A0A7I2V5T3_HUMAN,tr|H7C4K3|H7C4K3_HUMAN,tr|E7EUI6|E7EUI6_HUMAN,tr|E9PEE8|E9PEE8_HUMAN,tr|A0A7I2V5Z8|A0A7I2V5Z8_HUMAN,tr|A0A7I2V348|A0A7I2V348_HUMAN,tr|C9JPK5|C9JPK5_HUMAN" 11 990.5266 2.24 3755 16452 2 990.529092 496.2706 Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1 PE=1 SV=2 6 3326.4 - 607114 - - - 2.533 - 1.626 0.266 - 94.7 1 2 0 0.0025 9 0 0 0 1.83E+07 8.13E+06 - - - 2.4113 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.16459.16459.2 0.00515 20-Sep K.VLEVPPVVYSR.Q "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1256.7129 0.59 3760 16459 2 1256.71652 629.3637 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 5.97 3327.1 - 358690 - - - 2.902 - 1.735 0.35 - 199.8 1 2 0 0.0036 11 0 0 0 1.13E+07 1.91E+07 - - - 3.1156 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.16470.16470.2 0.541 18-Oct K.LVALAVIDEK[136.11].N sp|Q96JJ7|TMX3_HUMAN 1 1077.6525 1.82 3767 16470 2 1077.652113 539.8335 Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2 4.37 3328.5 - 234311 - - - -0.3693 - 2.043 0.372 - 184.6 1 2 0 -0.0004 10 0 0 0 1.54E+07 8.44E+06 - - - 3.7826 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.16472.16472.2 0.177 12-Sep R.LSAILFK.L "sp|Q9NSV4|DIAP3_HUMAN,sp|Q12830|BPTF_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|J3KSK9|J3KSK9_HUMAN,tr|J3QQQ8|J3QQQ8_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN" 7 790.4953 1.28 3769 16472 2 790.496606 396.2549 Protein diaphanous homolog 3 OS=Homo sapiens OX=9606 GN=DIAPH3 PE=1 SV=4 8.75 3328.7 - 1.59E+06 - - - 1.6825 - 1.55 0.122 - 238.7 1 2 0 0.0013 7 0 0 0 1.86E+07 1.45E+07 - - - 1.3303 0.9959 230117_WJC_METTL3_WT_vs_EV_F01.16473.16473.2 0.0263 16-Sep R.IGFGSFVEK.T "sp|P05556|ITB1_HUMAN,sp|P18564|ITB6_HUMAN,tr|A0A7I2V2F9|A0A7I2V2F9_HUMAN,tr|A0A087WXP3|A0A087WXP3_HUMAN,tr|A0A7I2V5T3|A0A7I2V5T3_HUMAN,tr|H7C4K3|H7C4K3_HUMAN,tr|E7EUI6|E7EUI6_HUMAN,tr|E9PEE8|E9PEE8_HUMAN,tr|A0A7I2V5Z8|A0A7I2V5Z8_HUMAN,tr|A0A7I2V348|A0A7I2V348_HUMAN,tr|C9JPK5|C9JPK5_HUMAN" 11 982.5124 2.32 3770 16473 2 982.511057 492.2635 Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1 PE=1 SV=2 6 3328.9 - 1.05E+06 - - - -1.3496 - 1.486 0.271 - 138.1 1 2 0 -0.0013 9 0 0 0 1.97E+07 8.51E+06 - - - 2.1881 0.996 230117_WJC_METTL3_WT_vs_EV_F01.16483.16483.2 0.0656 20-Nov R.IDALLAVDPPR[166.11].A sp|P50219|MNX1_HUMAN 1 1188.6742 2.17 3778 16483 2 1188.680445 595.3444 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3330.1 - 455165 - - - 5.2596 - 2.112 0.302 - 378.4 1 2 0 0.0063 11 0 0 0 4.70E+07 2.16E+07 - - - 3.2921 0.9838 230117_WJC_METTL3_WT_vs_EV_F01.16488.16488.2 1.7 14-Jul R.ALDIPLVK.N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 867.543 1.2 3781 16488 2 867.544909 434.7788 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3330.7 - 5.11E+06 - - - 2.2535 - 1.188 0.097 - 164.2 1 2 0 0.002 8 0 0 0 8.19E+07 6.80E+07 - - - 0.2764 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.16491.16491.2 0.0162 18-Nov K.LVALAVIDEK.N sp|Q96JJ7|TMX3_HUMAN 1 1069.6383 1.82 3784 16491 2 1069.639767 535.8264 Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2 4.37 3330.9 - 1.27E+06 - - - 1.3612 - 2.08 0.155 - 235.6 2 2 0 0.0015 10 0 0 0 1.54E+07 8.44E+06 - - - 2.0952 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.16494.16494.2 0.000695 16-Oct R.SLFVVVGDR.G "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 990.5498 0.35 3787 16494 2 990.554753 496.2822 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.55 3331.2 - 1.16E+06 - - - 4.969 - 2.1 0.394 - 380.2 1 2 0 0.0049 9 0 0 0 2.53E+07 7.20E+07 - - - 4.096 0.9467 230117_WJC_METTL3_WT_vs_EV_F01.16495.16495.2 2.57 12-May R.LFEGIIK.G "sp|O14936|CSKP_HUMAN,tr|A0A2U3TZM1|A0A2U3TZM1_HUMAN,tr|A0A2R8YFN5|A0A2R8YFN5_HUMAN,tr|A0A2R8YEK3|A0A2R8YEK3_HUMAN,tr|A0A2R8YE77|A0A2R8YE77_HUMAN,tr|A0A2R8Y6F8|A0A2R8Y6F8_HUMAN,tr|Q5JS79|Q5JS79_HUMAN,tr|A0A2R8Y3B3|A0A2R8Y3B3_HUMAN,tr|A0A2R8Y6D8|A0A2R8Y6D8_HUMAN,tr|A0A2U3TZN6|A0A2U3TZN6_HUMAN,tr|A0A2U3TZM4|A0A2U3TZM4_HUMAN,tr|A0A2R8YEJ7|A0A2R8YEJ7_HUMAN,tr|A0A7I2RJN6|A0A7I2RJN6_HUMAN" 13 818.4902 0.35 3788 16495 2 818.491905 410.2524 Peripheral plasma membrane protein CASK OS=Homo sapiens OX=9606 GN=CASK PE=1 SV=3 6 3331.3 - 1.06E+06 - - - 2.0941 - 1.39 0.005 - 56.1 32 2 0 0.0017 7 0 0 0 1.53E+07 4.40E+07 - - - -0.5515 0.9456 230117_WJC_METTL3_WT_vs_EV_F01.16497.16497.2 0.21 22-Apr R.MPGSVIPPPLVR[166.11].G sp|Q86YP4|P66A_HUMAN 1 1271.7299 2.58 3790 16497 2 1271.730265 636.8722 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.5 3331.6 - 177856 - - - 0.2603 - 1.079 0.14 - 23.4 52 2 0 0.0003 12 0 0 0 1.65E+07 6.38E+06 - - - -0.4915 0.9689 230117_WJC_METTL3_WT_vs_EV_F01.16499.16499.2 0.0022 26-Sep F.LLIGGGTAAFAAAR.S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1287.7299 6.26 3792 16499 2 1287.732303 644.8722 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3331.8 - 143534 - - - 1.8505 - 1.719 0.441 - 208.5 1 1 0 0.0024 14 0 0 0 1.53E+07 2.44E+06 - - - 3.657 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.16501.16501.2 0.00586 14-Oct K.VTNLLMLK.G "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|B4DI28|B4DI28_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|X6R242|X6R242_HUMAN,tr|A0A6Q8PH43|A0A6Q8PH43_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 18 930.5572 1.18 3793 16501 2 930.558908 466.2859 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.72 3332.1 - 4.44E+07 - - - 1.8097 - 2.072 0.334 - 326.5 1 2 0 0.0017 8 0 0 0 7.90E+08 6.72E+08 - - - 3.7046 0.9878 230117_WJC_METTL3_WT_vs_EV_F01.16503.16503.2 0.919 12-Jul R.LLLDSLR.K sp|Q10469|MGAT2_HUMAN 1 828.5069 1.11 3794 16503 2 828.509005 415.2607 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 5.84 3332.3 - 2.40E+06 - - - 2.5371 - 1.425 0.055 - 159.5 1 2 0 0.0021 7 0 0 0 4.16E+07 3.74E+07 - - - 0.5688 0.9869 230117_WJC_METTL3_WT_vs_EV_F01.16504.16504.2 0.552 12-Jul R.LLLDSLR[166.11].K sp|Q10469|MGAT2_HUMAN 1 838.5152 1.12 3795 16504 2 838.517464 420.2649 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 5.84 3332.4 - 2.44E+06 - - - 2.7322 - 1.438 0.055 - 159.8 1 2 0 0.0023 7 0 0 0 4.19E+07 3.75E+07 - - - 0.5975 0.9938 230117_WJC_METTL3_WT_vs_EV_F01.16505.16505.2 0.0115 12-Aug R.EAYYWLR[166.11].H sp|P46977|STT3A_HUMAN 1 1009.4897 1.35 3796 16505 2 1009.491399 505.7521 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6.1 3332.5 - 1.49E+06 - - - 1.6959 - 1.519 0.063 - 244.6 1 2 0 0.0017 7 0 0 0 4.56E+07 3.38E+07 - - - 0.8304 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.16510.16510.2 0.0112 16-Aug R.SLFVVVGDR[166.11].G "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 1000.5581 0.76 3800 16510 2 1000.560759 501.2863 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.55 3333.1 - 1.81E+06 - - - 2.6565 - 1.714 0.244 - 214.3 1 2 0 0.0027 9 0 0 0 2.12E+07 2.77E+07 - - - 2.4012 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.16512.16512.2 1.03 14-Aug R.ALDIPLVK[136.11].N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 875.5572 1.2 3802 16512 2 875.559178 438.7859 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3333.2 - 3.75E+06 - - - 2.3117 - 1.599 0.207 - 198.6 1 2 0 0.002 8 0 0 0 8.19E+07 6.80E+07 - - - 1.9849 0.968 230117_WJC_METTL3_WT_vs_EV_F01.16513.16513.2 0.0552 12-Jun R.EAYYWLR.H sp|P46977|STT3A_HUMAN 1 999.4814 1.35 3803 16513 2 999.48316 500.748 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6.1 3333.3 - 1.81E+06 - - - 1.7439 - 1.187 0.018 - 155.3 1 2 0 0.0017 7 0 0 0 4.56E+07 3.38E+07 - - - -0.2834 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.16518.16518.2 0.0283 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 0.95 3807 16518 2 1235.763098 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3333.9 - 2.02E+06 - - - 2.3791 - 1.933 0.262 - 254.5 1 2 0 0.0029 11 0 0 0 8.38E+07 8.86E+07 - - - 2.7582 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.16525.16525.2 0.0545 12-Aug K.FVSFLGR[166.11].T "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 834.4627 1.12 3811 16525 2 834.46356 418.2386 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 9.75 3334.7 - 1.91E+06 - - - 0.9779 - 1.497 0.326 - 207 1 2 0 0.0008 7 0 0 0 3.06E+08 2.72E+08 - - - 2.727 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.16529.16529.2 0.00981 20-Aug K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 0.87 3814 16529 2 1245.771046 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3335.1 - 1.14E+06 - - - 2.1015 - 1.871 0.382 - 173 1 2 0 0.0026 11 0 0 0 1.88E+08 2.15E+08 - - - 3.5564 1 230117_WJC_METTL3_WT_vs_EV_F01.16531.16531.2 7.74E-08 26-Dec F.LLIGGGTAAFAAAR.S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1287.7299 6.26 3815 16531 2 1287.733488 644.8722 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3335.5 - 242883 - - - 2.7708 - 2.19 0.588 - 412.6 1 1 0 0.0036 14 0 0 0 1.53E+07 2.44E+06 - - - 5.35 1 230117_WJC_METTL3_WT_vs_EV_F01.16536.16536.2 1.84E-05 13/18 K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 10.06 3819 16536 2 1146.631467 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3336.1 - 3.05E+06 - - - 2.6094 - 2.311 0.506 - 467.6 1 2 0 0.003 10 0 0 0 1.70E+08 1.69E+07 - - - 5.1156 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.16543.16543.2 0.25 16-Jul R.LVLQYAPSA.- "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN" 2 960.528 - 3825 16543 2 960.530537 481.2713 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 5.52 3336.9 - 9.63E+06 - - - 2.6069 - 1.438 0.273 - 111.8 1 2 0 0.0025 9 0 0 0 - - - - - 2.1075 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.16544.16544.2 0.134 14-Jul R.LIGWGQIR[166.11].R "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 951.553 0.89 3826 16544 2 951.554871 476.7838 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 9.75 3336.9 - 5.57E+06 - - - 2.0125 - 1.347 0.216 - 132.5 1 2 0 0.0019 8 0 0 0 9.75E+07 1.10E+08 - - - 1.5342 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.16545.16545.2 0.00211 16-Aug R.SPVYLTVLK[136.11].H "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1026.6205 1.55 3827 16545 2 1026.623821 514.3175 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 8.31 3337 - 1.28E+06 - - - 3.2514 - 1.629 0.352 - 177.2 1 2 0 0.0033 9 0 0 0 2.46E+07 1.58E+07 - - - 3.0515 0.9899 230117_WJC_METTL3_WT_vs_EV_F01.16551.16551.2 0.0836 14-Sep K.VTNLLMLK[136.11].G "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|B4DI28|B4DI28_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|X6R242|X6R242_HUMAN,tr|A0A6Q8PH43|A0A6Q8PH43_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 18 938.5714 1.18 3831 16551 2 938.576883 470.293 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.72 3337.8 - 9.49E+06 - - - 5.8163 - 1.506 0.312 - 234.5 1 2 0 0.0055 8 0 0 0 7.91E+08 6.72E+08 - - - 2.5786 0.9795 230117_WJC_METTL3_WT_vs_EV_F01.16552.16552.2 0.132 12-Jul K.LMFEELR[166.11].N sp|Q9Y3I0|RTCB_HUMAN 1 946.4822 1.11 3832 16552 2 946.487051 474.2484 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.53 3337.8 - 1.31E+06 - - - 5.1686 - 1.35 0.201 - 214.9 1 2 0 0.0049 7 0 0 0 5.29E+07 4.76E+07 - - - 1.4749 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.16553.16553.2 3.62 14-Jul K.VIILSLDR.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 927.5753 2.33 3833 16553 2 927.578881 464.7949 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.81 3337.9 - 1.80E+07 - - - 3.8423 - 1.792 0.276 - 187.5 1 2 0 0.0036 8 0 0 0 2.99E+08 1.28E+08 - - - 2.8377 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.16554.16554.2 0.0013 14-Aug K.VIFLENYR.V "sp|P06737|PYGL_HUMAN,sp|P11217|PYGM_HUMAN,sp|P11216|PYGB_HUMAN,tr|E9PK47|E9PK47_HUMAN,tr|H0Y4Z6|H0Y4Z6_HUMAN" 5 1052.5655 5.11 3834 16554 2 1052.569221 527.29 "Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL PE=1 SV=4" 5.97 3337.9 - 2.06E+06 - - - 3.5532 - 1.875 0.435 - 278.6 1 2 0 0.0037 8 0 0 0 8.66E+07 1.69E+07 - - - 4.1486 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.16560.16560.2 0.0015 16-Sep K.GPLMMYISK.M sp|P13639|EF2_HUMAN 1 1038.5242 0.18 3839 16560 2 1038.527817 520.2694 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 3338.7 - 2.62E+06 - - - 3.4732 - 1.949 0.442 - 366.5 1 2 0 0.0036 9 0 0 0 6.95E+07 3.96E+08 - - - 4.2351 0.986 230117_WJC_METTL3_WT_vs_EV_F01.16564.16564.2 0.633 12-Jun K.LPLLLSR.M "sp|P49902|5NTC_HUMAN,sp|O95866|G6B_HUMAN,tr|A0A140T9L8|A0A140T9L8_HUMAN,tr|A0A6Q8PHB5|A0A6Q8PHB5_HUMAN,tr|A0A140T9V1|A0A140T9V1_HUMAN,tr|A0A6Q8PHP0|A0A6Q8PHP0_HUMAN,tr|B7ZLJ5|B7ZLJ5_HUMAN,tr|A0A0G2JJG8|A0A0G2JJG8_HUMAN,tr|F8WDG3|F8WDG3_HUMAN,tr|Q5JUV4|Q5JUV4_HUMAN" 10 810.5327 0.79 3843 16564 2 810.53405 406.2736 Cytosolic purine 5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5C2 PE=1 SV=1 9.75 3338.9 - 426452 - - - 1.636 - 1.328 0.061 - 132.8 2 2 0 0.0013 7 0 0 0 1.86E+07 2.36E+07 - - - 0.2555 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.16566.16566.2 0.00166 16-Jul K.GLIDYETFK.E sp|P15924|DESP_HUMAN 1 1084.5441 2.03 3845 16566 2 1084.545606 543.2793 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3339.1 - 232028 - - - 1.4098 - 1.463 0.397 - 101.1 1 2 0 0.0015 9 0 0 0 8.93E+06 4.39E+06 - - - 3.0735 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.16569.16569.2 0.00093 16-Oct R.SAVYPLLYR.D "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H7C184|H7C184_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1080.5968 0.75 3847 16569 2 1080.602246 541.3057 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 8.31 3339.4 - 366892 - - - 5.0574 - 1.966 0.359 - 341.2 1 2 0 0.0055 9 0 0 0 6.91E+06 9.27E+06 - - - 3.6466 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.16574.16574.2 0.611 14-Sep K.LLELLPGK[136.11].V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 889.5728 2 3851 16574 2 889.575746 445.7937 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3340 - 1.71E+06 - - - 3.3061 - 1.368 0.288 - 226.6 1 2 0 0.0029 8 0 0 0 9.76E+07 4.88E+07 - - - 2.1123 1 230117_WJC_METTL3_WT_vs_EV_F01.16578.16578.2 0.000133 16-Oct K.GPLMMYISK[136.11].M sp|P13639|EF2_HUMAN 1 1046.5384 0.15 3853 16578 2 1046.53949 524.2765 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 3340.5 - 531886 - - - 1.032 - 1.874 0.511 - 303 1 2 0 0.0011 9 0 0 0 7.12E+07 4.82E+08 - - - 4.632 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.16586.16586.2 0.00126 12-Jul K.YYTLFGR.S sp|P07814|SYEP_HUMAN 1 918.46 1.14 3859 16586 2 918.460908 460.2373 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.59 3341.4 - 1.17E+06 - - - 1.0398 - 1.27 0.427 - 153.6 1 2 0 0.001 7 0 0 0 9.62E+07 8.42E+07 - - - 2.9519 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.16592.16592.2 0.877 14-Sep K.LLELLPGK.V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 881.5586 2 3863 16592 2 881.561908 441.7866 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3342.1 - 828536 - - - 3.7468 - 1.801 0.19 - 239.2 1 2 0 0.0033 8 0 0 0 9.76E+07 4.88E+07 - - - 2.2177 0.999 230117_WJC_METTL3_WT_vs_EV_F01.16593.16593.2 0.000534 18-Aug K.AAPEMVSLLK[136.11].R "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN,tr|K7EQ99|K7EQ99_HUMAN" 3 1065.5984 1.21 3864 16593 2 1065.602141 533.8065 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 6.05 3342.1 - 905501 - - - 3.5417 - 1.663 0.425 - 191.3 1 2 0 0.0038 10 0 0 0 6.37E+07 5.27E+07 - - - 3.5986 0.9798 230117_WJC_METTL3_WT_vs_EV_F01.16596.16596.2 2.41 16-Jun R.LIPDFPVAR.S sp|Q96S55|WRIP1_HUMAN 1 1026.5862 5.38 3867 16596 2 1026.586705 514.3004 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 5.84 3342.5 - 302937 - - - 0.4763 - 1.252 0.056 - 87.2 1 2 0 0.0005 9 0 0 0 5.32E+07 9.88E+06 - - - 0.1047 0.988 230117_WJC_METTL3_WT_vs_EV_F01.16604.16604.2 0.034 16-Aug K.FGLFTPGSR.L "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 980.508 0.81 3873 16604 2 980.514274 491.2613 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 9.75 3343.3 - 3.75E+06 - - - 6.4334 - 1.337 0.404 - 161.6 1 2 0 0.0063 9 0 0 0 1.74E+08 2.16E+08 - - - 2.8632 0.9922 230117_WJC_METTL3_WT_vs_EV_F01.16605.16605.2 0.156 16-Aug K.NAIVVLIPK[136.11].Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 973.6416 2.28 3874 16605 2 973.647231 487.8281 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3343.5 - 731260 - - - 5.8317 - 1.499 0.365 - 132.8 1 2 0 0.0057 9 0 0 0 1.74E+08 7.63E+07 - - - 2.9062 0.9924 230117_WJC_METTL3_WT_vs_EV_F01.16607.16607.2 0.00117 20-Aug R.LVMELSGEMVR.K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1262.6363 1.87 3876 16607 2 1262.644703 632.3254 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3343.7 - 251380 - - - 6.6718 - 1.62 0.463 - 155.5 1 2 0 0.0084 11 0 0 0 1.59E+07 8.48E+06 - - - 3.7631 0.9387 230117_WJC_METTL3_WT_vs_EV_F01.16608.16608.2 0.0144 20-May R.LVMELSGEMVR[166.11].K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1272.6445 1.89 3877 16608 2 1272.653002 637.3296 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3343.9 - 211856 - - - 6.6421 - 1.491 0.241 - 54.5 17 2 0 0.0085 11 0 0 0 1.58E+07 8.39E+06 - - - 1.3493 0.9962 230117_WJC_METTL3_WT_vs_EV_F01.16615.16615.2 0.015 12-Aug R.SFDLLVK.N sp|Q9HB71|CYBP_HUMAN 1 820.4695 2.12 3882 16615 2 820.473107 411.242 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 5.55 3344.8 - 1.24E+07 - - - 4.4511 - 1.501 0.313 - 232.5 1 2 0 0.0037 7 0 0 0 1.40E+08 6.59E+07 - - - 2.6385 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.16633.16633.2 0.0754 16-Dec K.NAIVVLIPK.Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 965.6274 2.28 3898 16633 2 965.630667 483.821 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3346.8 - 8.51E+06 - - - 3.432 - 2.029 0.447 - 551.9 1 2 0 0.0033 9 0 0 0 1.74E+08 7.63E+07 - - - 4.3885 0.9588 230117_WJC_METTL3_WT_vs_EV_F01.16634.16634.2 0.441 12-Jun K.NLFELAR.Q "sp|Q9UN37|VPS4A_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 2 861.4709 5.68 3899 16634 2 861.474429 431.7427 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 6 3346.9 - 1.20E+06 - - - 4.1522 - 1.165 0.139 - 112.8 2 2 0 0.0036 7 0 0 0 5.19E+07 9.14E+06 - - - 0.416 0.999 230117_WJC_METTL3_WT_vs_EV_F01.16637.16637.2 0.00728 20-Sep K.LISSVDPQFLK[136.11].L "sp|Q9BVG4|PBDC1_HUMAN,tr|A6NDF3|A6NDF3_HUMAN" 2 1253.7111 6.56 3902 16637 2 1253.712734 627.8628 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 5.84 3347.3 - 567603 - - - 1.3121 - 1.42 0.329 - 178 1 2 0 0.0016 11 0 0 0 2.97E+07 4.53E+06 - - - 2.4191 0.9942 230117_WJC_METTL3_WT_vs_EV_F01.16638.16638.2 0.0778 20-Aug R.VPLIGSLPEAR[166.11].L "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN,tr|K7EQG1|K7EQG1_HUMAN" 3 1160.6793 0.78 3903 16638 2 1160.68402 581.3469 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 5.97 3347.4 - 405116 - - - 4.0847 - 1.647 0.211 - 165.8 1 2 0 0.0047 11 0 0 0 4.30E+06 5.52E+06 - - - 1.9477 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.16646.16646.2 0.0917 20-Aug K.LISSVDPQFLK.L "sp|Q9BVG4|PBDC1_HUMAN,tr|A6NDF3|A6NDF3_HUMAN" 2 1245.6969 6.56 3909 16646 2 1245.698771 623.8557 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 5.84 3348.3 - 1.42E+06 - - - 1.5108 - 1.488 0.165 - 112.4 1 2 0 0.0019 11 0 0 0 2.97E+07 4.53E+06 - - - 1.3342 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.16647.16647.2 0.0139 16-Jul K.VYLGDIPLK[136.11].T "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1024.6048 1.61 3910 16647 2 1024.605754 513.3097 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.81 3348.3 - 1.11E+06 - - - 0.8989 - 1.281 0.241 - 162.3 1 2 0 0.0009 9 0 0 0 3.94E+07 2.44E+07 - - - 1.5372 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.16652.16652.2 0.0297 14-Sep R.IGVDLIMK.T "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 887.515 1.1 3913 16652 2 887.516707 444.7648 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.84 3348.9 - 1.96E+06 - - - 1.8952 - 1.381 0.284 - 153.3 1 2 0 0.0017 8 0 0 0 3.92E+07 3.57E+07 - - - 2.1117 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.16658.16658.2 0.00701 16-Oct R.LLQSLLDTR.C sp|Q13045|FLII_HUMAN 1 1057.6132 1.64 3917 16658 2 1057.616082 529.8139 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3349.6 - 3.49E+06 - - - 2.7638 - 1.93 0.394 - 335.6 1 2 0 0.0029 9 0 0 0 1.46E+07 8.88E+06 - - - 3.8524 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.16661.16661.2 0.00137 20-Oct K.ALTLIAGSPLK.L "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1082.6699 0.06 3920 16661 2 1082.670057 542.3422 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 8.8 3349.8 - 2.10E+06 - - - 0.1025 - 2.062 0.358 - 269.2 1 2 0 0.0001 11 0 0 0 2.00E+07 3.27E+08 - - - 3.6429 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.16669.16669.2 0.0478 16-Sep R.IGGISGIFK[136.11].S sp|Q9UK59|DBR1_HUMAN 1 898.5368 1.38 3926 16669 2 898.536007 450.2757 Lariat debranching enzyme OS=Homo sapiens OX=9606 GN=DBR1 PE=1 SV=2 8.75 3350.8 - 1.39E+06 - - - -0.8302 - 1.697 0.368 - 118.3 1 2 0 -0.0007 9 0 0 0 3.22E+07 2.33E+07 - - - 3.2888 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.16670.16670.2 0.000228 20-Oct K.NALESYAFNMK.S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1286.5965 999 3927 16670 2 1286.600476 644.3055 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3351 - 465692 - - - 3.0724 - 2.231 0.383 - 330.7 1 2 0 0.004 11 0 0 0 2.73E+07 0.00E+00 - - - 4.0394 0.9845 230117_WJC_METTL3_WT_vs_EV_F01.16671.16671.2 1.73 14-Aug R.DAFLTLAR.D "sp|Q92793|CBP_HUMAN,sp|Q09472|EP300_HUMAN,tr|A0A669KB12|A0A669KB12_HUMAN" 3 905.4971 2.14 3928 16671 2 905.494151 453.7558 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 5.84 3351.1 - 368147 - - - -3.2203 - 1.757 0.175 - 232.1 1 2 0 -0.0029 8 0 0 0 3.51E+07 1.64E+07 - - - 2.0324 0.9884 230117_WJC_METTL3_WT_vs_EV_F01.16674.16674.2 0.224 12-Aug K.VFDLLNR[166.11].K "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|H0Y8H2|H0Y8H2_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 885.4948 1.03 3929 16674 2 885.493569 443.7547 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 5.81 3351.5 - 759261 - - - -1.3586 - 1.357 0.171 - 209.5 1 2 0 -0.0012 7 0 0 0 2.73E+07 2.66E+07 - - - 1.2709 0.9796 230117_WJC_METTL3_WT_vs_EV_F01.16696.16696.2 0.318 12-Jul R.DLIDYVR.Y "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 892.4654 1.91 3940 16696 2 892.464372 447.24 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.21 3354.2 - 2.14E+06 - - - -1.1877 - 1.27 0.129 - 180.6 1 2 0 -0.0011 7 0 0 0 8.36E+07 4.37E+07 - - - 0.7508 0.9942 230117_WJC_METTL3_WT_vs_EV_F01.16706.16706.2 0.00105 22-Oct K.VFGAAPLENVVR.K "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 1270.7034 5.39 3945 16706 2 1270.700227 636.359 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 5.97 3355.5 - 0 - - - -2.4742 - 1.852 0.26 - 261.7 1 2 0 -0.0031 12 0 0 0 1.27E+08 2.36E+07 - - - 2.5819 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.16714.16714.2 0.0107 24-Nov K.VLIIGGGDGGVLR.E "sp|P19623|SPEE_HUMAN,tr|K7ESL0|K7ESL0_HUMAN" 2 1224.719 49 3948 16714 2 1224.716517 613.3668 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.81 3356.4 - 5.35E+06 - - - -2.0446 - 1.915 0.406 - 359.2 1 2 0 -0.0025 13 0 0 0 1.05E+08 2.14E+06 - - - 3.7064 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.16719.16719.2 0.00392 14-Oct R.IPQLLLER[166.11].Y "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 990.6101 1.08 3951 16719 2 990.609225 496.3123 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 6 3356.9 - 5.12E+06 - - - -0.9196 - 1.821 0.305 - 469 1 2 0 -0.0009 8 0 0 0 1.39E+08 1.29E+08 - - - 3.1012 0.9805 230117_WJC_METTL3_WT_vs_EV_F01.16730.16730.2 0.466 14-Aug K.GYGFGLIK.L "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 853.4698 1.36 3952 16730 2 853.467949 427.7422 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 3358.4 - 7.25E+06 - - - -2.1571 - 1.204 0.224 - 173.4 1 2 0 -0.0018 8 0 0 0 7.36E+08 5.40E+08 - - - 1.2548 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.16733.16733.2 0.0176 16-Nov R.LGC[160.03]FNLTIK[136.11].G sp|Q13547|HDAC1_HUMAN 1 1072.5831 0.5 3954 16733 2 1072.58335 537.2988 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 8.22 3358.7 - 946392 - - - 0.2778 - 1.865 0.256 - 256.7 1 2 0 0.0003 9 0 0 0 3.31E+07 6.67E+07 - - - 2.7348 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.16742.16742.2 3.25 18-Oct R.LYLINSPVVR.A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1172.6917 1.54 3956 16742 2 1172.693477 587.3531 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3360 - 7.75E+06 - - - 1.4778 - 2.031 0.263 - 443.5 1 2 0 0.0017 10 0 0 0 5.00E+08 3.24E+08 - - - 2.9607 0.9969 230117_WJC_METTL3_WT_vs_EV_F01.16743.16743.2 0.00011 18-Sep R.LYLINSPVVR[166.11].A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1182.7 1.54 3957 16743 2 1182.697908 592.3573 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3360.1 - 7.36E+06 - - - -1.7807 - 1.992 0.246 - 306.9 1 2 0 -0.0021 10 0 0 0 5.00E+08 3.24E+08 - - - 2.7809 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.16745.16745.2 0.148 14-Aug K.MALPELVR.A sp|P45974|UBP5_HUMAN 1 927.5212 18.21 3959 16745 2 927.525086 464.7679 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 5.75 3360.4 - 0 - - - 4.2188 - 1.632 0.276 - 159.5 1 2 0 0.0039 8 0 0 0 1.77E+07 9.69E+05 - - - 2.5555 0.8831 230117_WJC_METTL3_WT_vs_EV_F01.16754.16754.2 0.435 12-Jun K.ELLIFNK[136.11].Q "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 883.5259 1.11 3961 16754 2 883.524395 442.7702 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.1 3361.7 - 2.82E+06 - - - -1.6513 - 1.213 0.008 - 134.4 1 2 0 -0.0015 7 0 0 0 5.75E+08 5.16E+08 - - - -0.2885 0.988 230117_WJC_METTL3_WT_vs_EV_F01.16759.16759.2 0.977 14-Oct K.IPLGLDLK.N "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 867.543 1.52 3962 16759 2 867.541991 434.7788 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.84 3362.4 - 0 - - - -1.11 - 1.727 0.058 - 338 1 2 0 -0.001 8 0 0 0 1.33E+08 8.77E+07 - - - 1.117 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.16765.16765.2 0.0173 14-Sep R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 7851.52 3964 16765 2 1000.560188 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3363.2 - 8.54E+09 - - - 0.8545 - 2.101 0.319 - 274.9 1 2 0 0.0009 8 0 0 0 5.52E+11 7.03E+07 - - - 3.636 1 230117_WJC_METTL3_WT_vs_EV_F01.16775.16775.2 0.000992 18-Nov R.VAAAVDLIIK.S "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1011.6328 1.9 3965 16775 2 1011.626671 506.8237 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3364.8 - 5.98E+06 - - - -6.0902 - 2.508 0.473 - 379.5 1 2 0 -0.0062 10 0 0 0 1.29E+08 6.78E+07 - - - 5.0992 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.16776.16776.2 0.000293 18-Aug R.GTPLISPLIK[136.11].W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1045.6627 1.8 3966 16776 2 1045.659342 523.8386 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3364.9 - 3.45E+06 - - - -3.1941 - 1.685 0.455 - 223.9 1 2 0 -0.0033 10 0 0 0 2.57E+08 1.43E+08 - - - 3.857 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.16777.16777.2 0.00375 18-Oct R.GTPLISPLIK.W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1037.6485 1.81 3967 16777 2 1037.646378 519.8315 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3365 - 4.97E+06 - - - -2.0277 - 1.754 0.434 - 372.9 1 2 0 -0.0021 10 0 0 0 2.57E+08 1.43E+08 - - - 3.8143 0.9704 230117_WJC_METTL3_WT_vs_EV_F01.16779.16779.2 0.0595 14-Jun R.VAFTLLEK.V "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 4 919.5379 12.19 3969 16779 2 919.534222 460.7762 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 5.97 3365.2 - 1.27E+06 - - - -3.9661 - 1.482 0.22 - 90.6 1 2 0 -0.0036 8 0 0 0 7.72E+07 6.33E+06 - - - 1.8512 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.16780.16780.2 0.000285 18-Sep K.IFFAGDTIPK.S "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 5 1107.5964 2.42 3970 16780 2 1107.594772 554.8055 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.84 3365.4 - 773160 - - - -1.5123 - 1.845 0.44 - 171.6 1 2 0 -0.0017 10 0 0 0 1.04E+08 4.29E+07 - - - 3.9999 0.8509 230117_WJC_METTL3_WT_vs_EV_F01.16786.16786.2 0.967 16-Jul K.VEDLLPIMK.Q "sp|Q8NBP0|TTC13_HUMAN,tr|H0YB10|H0YB10_HUMAN" 2 1056.5889 51.68 3972 16786 2 1056.583382 529.3017 Tetratricopeptide repeat protein 13 OS=Homo sapiens OX=9606 GN=TTC13 PE=2 SV=3 4.37 3366.1 - 2.34E+06 - - - -5.2395 - 1.348 0.157 - 162.5 1 2 0 -0.0055 9 0 0 0 2.14E+08 4.14E+06 - - - 1.0628 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.16787.16787.2 1.16E-05 18-Nov R.YGLAAAVFTR.D sp|P30837|AL1B1_HUMAN 1 1067.5764 3.94 3973 16787 2 1067.573521 534.7955 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 8.75 3366.3 - 957126 - - - -2.678 - 2.352 0.355 - 400.7 1 2 0 -0.0029 10 0 0 0 4.03E+07 1.02E+07 - - - 4.0494 0.9929 230117_WJC_METTL3_WT_vs_EV_F01.16789.16789.2 0.0232 12-Jun K.FTVPMLK[136.11].E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 842.4815 0.88 3975 16789 2 842.479662 422.248 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3366.5 - 1.25E+06 - - - -2.2374 - 1.41 0.281 - 123.9 1 2 0 -0.0019 7 0 0 0 1.47E+08 1.67E+08 - - - 2.2046 0.989 230117_WJC_METTL3_WT_vs_EV_F01.16792.16792.2 0.888 16-Aug K.GSLLPTSPR.L "tr|H7C179|H7C179_HUMAN,tr|H7C128|H7C128_HUMAN,tr|H7C127|H7C127_HUMAN" 3 926.5185 1.57 3976 16792 2 926.518286 464.2665 Bromodomain-containing protein 8 (Fragment) OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=1 9.75 3366.9 - 1.40E+06 - - - -0.2644 - 1.459 0.088 - 183.1 1 2 0 -0.0002 9 0 0 0 2.40E+08 1.53E+08 - - - 0.7837 0.9537 230117_WJC_METTL3_WT_vs_EV_F01.16797.16797.2 2.91 16-Jun K.GSLLPTSPR[166.11].L "tr|H7C179|H7C179_HUMAN,tr|H7C128|H7C128_HUMAN,tr|H7C127|H7C127_HUMAN" 3 936.5268 1.51 3980 16797 2 936.5276 469.2707 Bromodomain-containing protein 8 (Fragment) OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=1 9.75 3367.4 - 1.33E+06 - - - 0.8532 - 1.242 0.012 - 72.9 4 2 0 0.0008 9 0 0 0 2.36E+08 1.57E+08 - - - -0.5126 1 230117_WJC_METTL3_WT_vs_EV_F01.16802.16802.2 0.000176 13/20 R.FGGLVLSPVGK.Q sp|Q9UJK0|TSR3_HUMAN 1 1072.6281 1.35 3982 16802 2 1072.627335 537.3213 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.75 3368 - 1.63E+06 - - - -0.6955 - 2.488 0.541 - 561.9 1 2 0 -0.0007 11 0 0 0 6.35E+07 4.71E+07 - - - 5.5024 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.16804.16804.2 0.00407 12-Aug K.FTVPMLK.E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 834.4673 0.87 3984 16804 2 834.467773 418.2409 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3368.3 - 2.04E+06 - - - 0.5105 - 1.553 0.272 - 222 1 2 0 0.0004 7 0 0 0 1.43E+08 1.66E+08 - - - 2.4446 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.16805.16805.2 0.191 20-Aug K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.12 3985 16805 2 1245.7679 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3368.4 - 797528 - - - -0.4238 - 1.678 0.319 - 193.3 1 2 0 -0.0005 11 0 0 0 1.01E+08 8.99E+07 - - - 2.7972 1 230117_WJC_METTL3_WT_vs_EV_F01.16808.16808.2 1.47E-08 22-Nov R.GYISPYFINTSK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1388.6976 2.39 3986 16808 2 1388.700906 695.3561 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3368.8 - 1.67E+06 - - - 2.3684 - 2.359 0.526 - 458.4 1 2 0 0.0033 12 0 0 0 4.98E+07 2.09E+07 - - - 5.1832 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.16820.16820.2 0.0311 12-Jun K.LFDFPGR.G sp|Q9P258|RCC2_HUMAN 1 850.4337 2.25 3990 16820 2 850.433531 426.2241 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.84 3370.6 - 529953 - - - -0.2434 - 1.345 0.237 - 99.5 1 2 0 -0.0002 7 0 0 0 2.00E+08 8.87E+07 - - - 1.7306 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.16823.16823.2 0.00373 16-Nov K.LLC[160.03]GLLAER[166.11].L sp|P14174|MIF_HUMAN 1 1053.588 0.91 3991 16823 2 1053.586841 527.8013 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3371 - 3.79E+06 - - - -1.12 - 2.147 0.261 - 414.9 1 2 0 -0.0012 9 0 0 0 1.22E+09 1.34E+09 - - - 3.1789 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.16824.16824.2 0.0038 16-Nov K.LLC[160.03]GLLAER.L sp|P14174|MIF_HUMAN 1 1043.5798 0.91 3992 16824 2 1043.578605 522.7972 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3371.1 - 2.22E+06 - - - -1.0981 - 2.127 0.412 - 425.8 1 2 0 -0.0011 9 0 0 0 1.22E+09 1.35E+09 - - - 4.2671 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.16829.16829.2 0.0491 16-Aug K.MMLDDIVSR.G "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 6 1078.5151 0.45 3995 16829 2 1078.515676 540.2648 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.21 3371.7 - 651858 - - - 0.5322 - 1.602 0.237 - 246.2 1 2 0 0.0006 9 0 0 0 2.46E+07 5.51E+07 - - - 2.1547 0.9949 230117_WJC_METTL3_WT_vs_EV_F01.16831.16831.2 0.0732 16-Aug R.GLFTGLTPR.L "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 960.5393 1.15 3996 16831 2 960.537365 481.2769 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3371.9 - 1.15E+06 - - - -1.9791 - 1.773 0.227 - 171.4 1 2 0 -0.0019 9 0 0 0 6.67E+07 5.82E+07 - - - 2.3738 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.16832.16832.2 0.0164 16-Aug R.GLFTGLTPR[166.11].L "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 970.5475 1.17 3997 16832 2 970.546566 486.281 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3372.1 - 692911 - - - -0.9994 - 1.756 0.241 - 185.4 1 2 0 -0.001 9 0 0 0 6.88E+07 5.88E+07 - - - 2.4496 0.9948 230117_WJC_METTL3_WT_vs_EV_F01.16835.16835.2 0.00776 20-Jul K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.14 3998 16835 2 1235.757023 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3372.5 - 563286 - - - -2.5369 - 1.67 0.314 - 144.8 1 2 0 -0.0031 11 0 0 0 4.97E+07 4.35E+07 - - - 2.7465 1 230117_WJC_METTL3_WT_vs_EV_F01.16839.16839.2 0.0524 18-Dec K.VYVIGSFVDK.S sp|Q7L0Y3|TM10C_HUMAN 1 1125.607 0.67 4000 16839 2 1125.607172 563.8108 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3373 - 408869 - - - 0.143 - 2.489 0.425 - 491.8 1 2 0 0.0002 10 0 0 0 3.70E+07 5.51E+07 - - - 4.7253 0.9932 230117_WJC_METTL3_WT_vs_EV_F01.16841.16841.2 0.015 14-Jul K.LGPLAFYK.G "sp|Q9UBX3|DIC_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 907.5167 1.62 4001 16841 2 907.519628 454.7656 Mitochondrial dicarboxylate carrier OS=Homo sapiens OX=9606 GN=SLC25A10 PE=1 SV=2 8.59 3373.2 - 2.13E+06 - - - 3.1823 - 1.741 0.078 - 128.2 1 2 0 0.0029 8 0 0 0 6.30E+07 3.88E+07 - - - 1.2884 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.16842.16842.2 0.00261 12-Jun R.FFLEYDR.L "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 988.4654 1.52 4002 16842 2 988.468192 495.24 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 4.37 3373.3 - 1.29E+06 - - - 2.7922 - 1.338 0.371 - 119.6 1 2 0 0.0028 7 0 0 0 2.98E+07 1.96E+07 - - - 2.7029 0.9881 230117_WJC_METTL3_WT_vs_EV_F01.16845.16845.2 0.00169 16-Sep R.YVANLFPYK.G "sp|Q15181|IPYR_HUMAN,sp|Q9H2U2|IPYR2_HUMAN,tr|D6RGV9|D6RGV9_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN,tr|D6RGI1|D6RGI1_HUMAN,tr|H0YAK2|H0YAK2_HUMAN" 7 1113.5859 2.96 4005 16845 2 1113.580749 557.8002 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 8.5 3373.6 - 1.24E+06 - - - -4.6094 - 1.504 0.425 - 192.4 1 2 0 -0.0051 9 0 0 0 1.09E+08 3.68E+07 - - - 3.3592 1 230117_WJC_METTL3_WT_vs_EV_F01.16851.16851.2 0.000766 18-Nov K.VYVIGSFVDK[136.11].S sp|Q7L0Y3|TM10C_HUMAN 1 1133.6212 0.67 4009 16851 2 1133.620585 567.8179 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3374.3 - 2.91E+06 - - - -0.5522 - 2.229 0.511 - 447.7 1 2 0 -0.0006 10 0 0 0 3.70E+07 5.51E+07 - - - 5.0524 0.97 230117_WJC_METTL3_WT_vs_EV_F01.16856.16856.2 0.773 12-Jul R.LTLLQLK.G sp|Q8NHP8|PLBL2_HUMAN 1 827.548 1.09 4012 16856 2 827.545721 414.7813 Putative phospholipase B-like 2 OS=Homo sapiens OX=9606 GN=PLBD2 PE=1 SV=2 8.75 3375 - 1.30E+06 - - - -2.8023 - 1.332 0.173 - 105.5 1 2 0 -0.0023 7 0 0 0 2.68E+07 2.45E+07 - - - 1.2264 0.9941 230117_WJC_METTL3_WT_vs_EV_F01.16861.16861.2 0.0433 12-Aug R.FVAELWK[136.11].D sp|P35580|MYH10_HUMAN 1 899.4996 0.75 4015 16861 2 899.497661 450.7571 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3375.7 - 704477 - - - -2.2001 - 1.539 0.266 - 198.3 1 2 0 -0.002 7 0 0 0 7.05E+07 9.40E+07 - - - 2.3711 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.16866.16866.2 0.0452 12-Jun K.LMIWDTR.S "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 933.4742 1.43 4018 16866 2 933.475137 467.7444 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3376.2 - 1.55E+06 - - - 0.9791 - 1.324 0.353 - 194.8 1 2 0 0.0009 7 0 0 0 2.42E+08 1.69E+08 - - - 2.5372 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.16869.16869.2 0.366 14-Aug R.LGISSLIR.E sp|P35573|GDE_HUMAN 1 857.5335 0.75 4019 16869 2 857.535008 429.774 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3376.6 - 1.02E+06 - - - 1.8145 - 1.479 0.138 - 124.5 1 2 0 0.0016 8 0 0 0 6.75E+07 9.06E+07 - - - 1.2401 0.9516 230117_WJC_METTL3_WT_vs_EV_F01.16876.16876.2 2.78 14-Jun K.IPLGLDLK[136.11].N "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 875.5572 1.9 4025 16876 2 875.556683 438.7859 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.84 3377.4 - 712971 - - - -0.5379 - 1.239 0.061 - 66.6 4 2 0 -0.0005 8 0 0 0 1.96E+08 1.03E+08 - - - -0.1312 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.16879.16879.2 1.07 12-Jun R.FVAELWK.D sp|P35580|MYH10_HUMAN 1 891.4854 0.73 4026 16879 2 891.486439 446.75 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3377.8 - 2.51E+06 - - - 1.1206 - 1.229 0.306 - 119 1 2 0 0.001 7 0 0 0 7.07E+07 9.66E+07 - - - 1.9542 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.16880.16880.2 0.00934 20-Oct K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.17 4027 16880 2 1245.768343 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3377.9 - 862092 - - - -0.0682 - 1.948 0.319 - 281 1 2 0 -0.0001 11 0 0 0 3.28E+07 2.80E+07 - - - 3.201 1 230117_WJC_METTL3_WT_vs_EV_F01.16881.16881.2 1.53E-05 20-Dec R.ALDEGDIALLK.T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1156.634 3.12 4028 16881 2 1156.636493 579.3243 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 3378.1 - 760514 - - - 2.1952 - 2.285 0.46 - 373.8 1 2 0 0.0025 11 0 0 0 2.31E+07 7.40E+06 - - - 4.6733 0.998 230117_WJC_METTL3_WT_vs_EV_F01.16885.16885.2 0.324 12-Jun R.GFELTFK[136.11].T "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 848.4524 1.1 4030 16885 2 848.45458 425.2335 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3378.6 - 455984 - - - 2.6224 - 1.347 0.281 - 121.7 1 2 0 0.0022 7 0 0 0 3.27E+07 2.98E+07 - - - 2.0596 0.9743 230117_WJC_METTL3_WT_vs_EV_F01.16887.16887.2 1.24 12-Aug K.LDDLFLK.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 862.48 0.87 4032 16887 2 862.478238 432.2473 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3378.8 - 935606 - - - -2.0661 - 1.532 0.081 - 215 1 2 0 -0.0018 7 0 0 0 1.43E+08 1.65E+08 - - - 0.9903 0.851 230117_WJC_METTL3_WT_vs_EV_F01.16895.16895.2 0.00179 16-Dec K.PLALVEEIR.N "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1038.6073 1.9 4038 16895 2 1038.612836 520.3109 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 4.53 3379.7 - 476299 - - - 5.2859 - 2.265 0.42 - 401.4 1 1 0 0.0055 9 0 0 0 1.30E+07 6.80E+06 - - - 4.5067 1 230117_WJC_METTL3_WT_vs_EV_F01.16897.16897.2 4.32E-05 20-Dec R.ALDEGDIALLK[136.11].T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1164.6482 3.16 4040 16897 2 1164.644702 583.3314 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 3380 - 388281 - - - -2.964 - 2.496 0.52 - 320.7 1 2 0 -0.0035 11 0 0 0 2.34E+07 7.40E+06 - - - 5.3551 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.16898.16898.2 0.0183 22-Jul R.VLIGNVQPGILR[166.11].F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1287.7902 2.35 4041 16898 2 1287.792208 644.9024 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3380.1 - 208764 - - - 1.5391 - 1.581 0.319 - 119.3 1 2 0 0.002 12 0 0 0 8.26E+06 3.51E+06 - - - 2.6017 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.16902.16902.2 0.0742 18-Sep R.VIAIDIDPVK.L sp|Q96RS0|TGS1_HUMAN 1 1081.6383 2.04 4043 16902 2 1081.637896 541.8264 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 4.21 3380.6 - 367406 - - - -0.3837 - 1.612 0.185 - 199.6 1 2 0 -0.0004 10 0 0 0 2.95E+07 1.45E+07 - - - 1.7401 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.16903.16903.2 0.0151 16-Jul R.YVANLFPYK[136.11].G "sp|Q15181|IPYR_HUMAN,sp|Q9H2U2|IPYR2_HUMAN,tr|D6RGV9|D6RGV9_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN,tr|D6RGI1|D6RGI1_HUMAN,tr|H0YAK2|H0YAK2_HUMAN" 7 1121.6001 3.05 4044 16903 2 1121.601268 561.8073 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 8.5 3380.6 - 790470 - - - 1.0574 - 1.338 0.268 - 146.7 1 2 0 0.0012 9 0 0 0 1.04E+08 3.42E+07 - - - 1.8625 0.9672 230117_WJC_METTL3_WT_vs_EV_F01.16904.16904.2 0.00943 16-Aug K.IDPEAFITR[166.11].H sp|Q92616|GCN1_HUMAN 1 1070.5636 1.15 4045 16904 2 1070.56171 536.2891 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3380.8 - 528693 - - - -1.7467 - 1.446 0.093 - 131 2 2 0 -0.0019 9 0 0 0 4.36E+07 3.80E+07 - - - 0.6598 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.16906.16906.2 0.00975 22-Nov R.VLIGNVQPGILR.F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1277.782 2.35 4047 16906 2 1277.785923 639.8983 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3381 - 155585 - - - 3.1046 - 2.228 0.391 - 381.4 1 2 0 0.004 12 0 0 0 8.26E+06 3.51E+06 - - - 4.0355 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.16911.16911.2 0.00353 14-Aug K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 0.79 4050 16911 2 988.574377 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3381.6 - 1.88E+06 - - - 3.8551 - 1.72 0.293 - 285.4 1 2 0 0.0038 8 0 0 0 5.52E+09 6.98E+09 - - - 2.8395 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.16912.16912.2 0.0013 18-Nov R.FGVITEVDIK[136.11].R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1127.6318 3.79 4051 16912 2 1127.63541 564.8232 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 4.37 3381.7 - 831630 - - - 3.2227 - 2.198 0.382 - 421 1 2 0 0.0036 10 0 0 0 6.11E+07 1.61E+07 - - - 4.0596 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.16914.16914.2 0.0172 18-Nov R.FGVITEVDIK.R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1119.6176 3.8 4053 16914 2 1119.619273 560.8161 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 4.37 3381.9 - 1.46E+06 - - - 1.5157 - 2.194 0.26 - 426.6 1 2 0 0.0017 10 0 0 0 6.14E+07 1.62E+07 - - - 3.154 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.16915.16915.2 0.0935 20-Oct K.LLAAFPGVTPR.V "sp|Q9Y2I1|NISCH_HUMAN,tr|C9J715|C9J715_HUMAN" 2 1140.6655 4.55 4054 16915 2 1140.66795 571.34 Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3 9.75 3382 - 384750 - - - 2.1224 - 1.827 0.232 - 256 1 2 0 0.0024 11 0 0 0 7.99E+06 1.76E+06 - - - 2.3842 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.16920.16920.2 0.00266 22-Jul R.MPGSVIPPPLVR.G sp|Q86YP4|P66A_HUMAN 1 1261.7217 7.58 4059 16920 2 1261.723278 631.8681 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.5 3382.6 - 89721.4 - - - 1.2792 - 1.518 0.339 - 111.6 1 2 0 0.0016 12 0 0 0 1.79E+06 2.36E+05 - - - 2.6426 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.16922.16922.2 1.84 12-Jul K.LDDLFLK[136.11].R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 870.4942 0.91 4060 16922 2 870.495706 436.2544 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3382.9 - 7.46E+06 - - - 1.7071 - 1.814 0.066 - 145 1 2 0 0.0015 7 0 0 0 1.38E+08 1.51E+08 - - - 1.415 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.16923.16923.2 0.00617 12-Jul K.LMIWDTR[166.11].S "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 943.4825 1.65 4061 16923 2 943.484772 472.7485 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3382.9 - 3.50E+06 - - - 2.4155 - 1.445 0.372 - 261.3 1 2 0 0.0023 7 0 0 0 2.42E+08 1.47E+08 - - - 2.9543 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.16924.16924.2 0.0901 14-Aug R.ILELDQFK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1012.5684 1.12 4062 16924 2 1012.570431 507.2915 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3382.9 - 1.29E+07 - - - 1.9594 - 1.472 0.321 - 141.2 1 2 0 0.002 8 0 0 0 3.62E+08 3.24E+08 - - - 2.5773 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.16927.16927.2 0.131 14-Jun K.LEPDILLR.A "sp|Q01433|AMPD2_HUMAN,tr|A0A7P0TB79|A0A7P0TB79_HUMAN,tr|A0A590UK85|A0A590UK85_HUMAN,tr|A0A5F9UK94|A0A5F9UK94_HUMAN,tr|E9PJF6|E9PJF6_HUMAN,tr|A0A590UJX5|A0A590UJX5_HUMAN,tr|H0Y360|H0Y360_HUMAN,tr|A0A7P0Z4H6|A0A7P0Z4H6_HUMAN,tr|E9PIJ1|E9PIJ1_HUMAN,tr|H0YF16|H0YF16_HUMAN,tr|A0A804CCZ3|A0A804CCZ3_HUMAN" 11 967.5702 3.07 4065 16927 2 967.572751 484.7924 AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2 4.37 3383.2 - 541777 - - - 2.6034 - 1.347 0.205 - 102.4 2 2 0 0.0025 8 0 0 0 1.51E+07 4.93E+06 - - - 1.3183 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.16928.16928.2 0.0828 18-Sep K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 112.8 4066 16928 2 1146.628234 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3383.3 - 475614 - - - -0.2102 - 1.666 0.249 - 164.2 1 2 0 -0.0002 10 0 0 0 7.83E+06 6.94E+04 - - - 2.3048 0.8762 230117_WJC_METTL3_WT_vs_EV_F01.16932.16932.2 0.661 14-May K.LEPDILLR[166.11].A "sp|Q01433|AMPD2_HUMAN,tr|A0A7P0TB79|A0A7P0TB79_HUMAN,tr|A0A590UK85|A0A590UK85_HUMAN,tr|A0A5F9UK94|A0A5F9UK94_HUMAN,tr|E9PJF6|E9PJF6_HUMAN,tr|A0A590UJX5|A0A590UJX5_HUMAN,tr|H0Y360|H0Y360_HUMAN,tr|A0A7P0Z4H6|A0A7P0Z4H6_HUMAN,tr|E9PIJ1|E9PIJ1_HUMAN,tr|H0YF16|H0YF16_HUMAN,tr|A0A804CCZ3|A0A804CCZ3_HUMAN" 11 977.5785 3.07 4070 16932 2 977.581615 489.7965 AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2 4.37 3383.9 - 312625 - - - 3.1844 - 1.134 0.045 - 44.6 14 2 0 0.0031 8 0 0 0 1.51E+07 4.93E+06 - - - -0.7603 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.16934.16934.2 2.64E-05 18-Oct K.C[160.03]LEPTVALLR[166.11].W "sp|Q8TCG1|CIP2A_HUMAN,tr|A0A087X211|A0A087X211_HUMAN" 2 1180.6514 2.04 4072 16934 2 1180.656475 591.333 Protein CIP2A OS=Homo sapiens OX=9606 GN=CIP2A PE=1 SV=2 5.99 3384.1 - 271371 - - - 4.3408 - 1.906 0.462 - 297.2 1 2 0 0.0051 10 0 0 0 1.71E+07 8.38E+06 - - - 4.2521 0.9933 230117_WJC_METTL3_WT_vs_EV_F01.16938.16938.2 1.07 14-Jun K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 0.79 4074 16938 2 998.581153 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3384.6 - 6.99E+07 - - - 2.3203 - 1.252 0.164 - 167.3 1 2 0 0.0023 8 0 0 0 5.50E+09 6.97E+09 - - - 0.9294 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.16939.16939.2 0.0629 14-Aug R.ILELDQFK.G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1004.5542 0.99 4075 16939 2 1004.555978 503.2844 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3384.7 - 1.47E+07 - - - 1.7232 - 1.821 0.32 - 162 1 2 0 0.0017 8 0 0 0 3.19E+08 3.22E+08 - - - 3.2117 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.16941.16941.2 0.0493 14-Jun K.VITLC[160.03]LYR.D sp|Q10570|CPSF1_HUMAN 1 1036.5739 0.24 4077 16941 2 1036.575275 519.2942 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.19 3384.8 - 1.09E+06 - - - 1.2908 - 1.119 0.256 - 96.3 1 2 0 0.0013 8 0 0 0 1.86E+07 7.60E+07 - - - 1.2705 0.9762 230117_WJC_METTL3_WT_vs_EV_F01.16943.16943.2 1.75 12-Jun R.KFDIDIR.L "sp|O00750|P3C2B_HUMAN,tr|Q5SW98|Q5SW98_HUMAN,tr|F5GWN5|F5GWN5_HUMAN" 3 905.4971 4.64 4079 16943 2 905.49919 453.7558 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta OS=Homo sapiens OX=9606 GN=PIK3C2B PE=1 SV=2 5.96 3384.9 - 804252 - - - 2.3446 - 1.128 0.113 - 83.3 3 2 0 0.0021 7 0 0 0 1.44E+07 3.11E+06 - - - 0.0435 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.16944.16944.2 0.000842 14-Sep R.VWDISGLR[166.11].K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 954.5162 2.98 4080 16944 2 954.517643 478.2654 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3385 - 661320 - - - 1.474 - 1.764 0.18 - 230.2 1 2 0 0.0014 8 0 0 0 1.06E+08 3.55E+07 - - - 2.0818 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.16951.16951.2 1.48 14-Jul R.DILLQGLK[136.11].A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 906.563 0.86 4085 16951 2 906.563625 454.2888 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3385.7 - 983740 - - - 0.7247 - 1.44 0.168 - 122.6 1 2 0 0.0007 8 0 0 0 2.59E+07 3.02E+07 - - - 1.3814 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.16953.16953.2 0.000487 18-Oct K.IVAFENAFER.L sp|O60763|USO1_HUMAN 1 1194.6033 1.05 4087 16953 2 1194.605096 598.3089 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 3386 - 864666 - - - 1.4842 - 2.037 0.364 - 258.4 1 2 0 0.0018 10 0 0 0 8.93E+06 8.49E+06 - - - 3.7149 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.16954.16954.2 0.00446 12-Jun K.FIDPFC[160.03]K.L sp|Q14684|RRP1B_HUMAN 1 925.4368 2.4 4088 16954 2 925.439802 463.7257 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.83 3386.1 - 1.16E+06 - - - 3.2709 - 1.122 0.304 - 96.5 1 2 0 0.003 7 0 0 0 4.23E+07 1.76E+07 - - - 1.6501 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.16955.16955.2 0.00163 16-Sep K.FLGELYNYR[166.11].M sp|Q9HAU5|RENT2_HUMAN 1 1183.5901 0.76 4089 16955 2 1183.591746 592.8023 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 6 3386.2 - 580969 - - - 1.3662 - 1.651 0.345 - 243.8 1 2 0 0.0016 9 0 0 0 8.15E+06 1.07E+07 - - - 3.0392 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.16956.16956.2 0.00021 18-Aug K.IVAFENAFER[166.11].L sp|O60763|USO1_HUMAN 1 1204.6116 1.05 4090 16956 2 1204.616851 603.3131 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 3386.3 - 517346 - - - 4.3649 - 1.72 0.379 - 129.7 1 2 0 0.0053 10 0 0 0 8.93E+06 8.49E+06 - - - 3.3524 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.16961.16961.2 0.000116 16-Aug R.ATLNAFLYR[166.11].T "sp|Q5T2N8|ATD3C_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 3 1077.5847 1.36 4093 16961 2 1077.586125 539.7996 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 8.79 3386.8 - 1.58E+06 - - - 1.3688 - 2.042 0.411 - 263.7 1 2 0 0.0015 9 0 0 0 7.46E+07 5.48E+07 - - - 4.1416 0.9869 230117_WJC_METTL3_WT_vs_EV_F01.16962.16962.2 0.674 14-Jul R.VWDISGLR.K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 944.508 2.98 4094 16962 2 944.511709 473.2613 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3386.9 - 4.35E+06 - - - 3.9629 - 1.571 0.105 - 210.3 1 2 0 0.0037 8 0 0 0 1.06E+08 3.56E+07 - - - 1.1777 0.9941 230117_WJC_METTL3_WT_vs_EV_F01.16963.16963.2 0.0159 12-Jul R.IPTAWFR.E "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN" 2 889.481 2.29 4095 16963 2 889.479097 445.7478 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 9.75 3386.9 - 1.70E+06 - - - -2.1653 - 1.313 0.33 - 178.9 1 2 0 -0.0019 7 0 0 0 2.41E+07 1.05E+07 - - - 2.3406 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.16969.16969.2 0.000416 18-Oct K.IEDMAVSLIR.E sp|Q15776|ZKSC8_HUMAN 1 1145.6114 0.56 4099 16969 2 1145.612902 573.813 Zinc finger protein with KRAB and SCAN domains 8 OS=Homo sapiens OX=9606 GN=ZKSCAN8 PE=1 SV=2 4.37 3387.6 - 700416 - - - 1.2718 - 2.136 0.362 - 261.7 1 2 0 0.0015 10 0 0 0 6.31E+06 1.12E+07 - - - 3.8327 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.16970.16970.2 0.0331 18-Jul K.AVFVPDIYSR.T sp|O94874|UFL1_HUMAN 1 1165.6132 1.82 4100 16970 2 1165.614214 583.8139 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.88 3387.7 - 303736 - - - 0.9051 - 1.569 0.25 - 117.1 1 2 0 0.0011 10 0 0 0 1.18E+07 6.49E+06 - - - 2.1445 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.16971.16971.2 0.129 14-Sep R.DILLQGLK.A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 898.5488 0.86 4101 16971 2 898.548806 450.2817 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3387.8 - 2.06E+06 - - - 0.0423 - 1.687 0.154 - 257.8 1 2 0 0 8 0 0 0 2.59E+07 3.02E+07 - - - 1.7556 0.999 230117_WJC_METTL3_WT_vs_EV_F01.16972.16972.2 0.0246 14-Jul K.YVVGLIIK[136.11].T "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 911.5935 1.36 4102 16972 2 911.593999 456.804 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3387.8 - 1.76E+06 - - - 0.5035 - 1.393 0.341 - 148.9 1 2 0 0.0005 8 0 0 0 6.27E+07 4.60E+07 - - - 2.5591 0.9888 230117_WJC_METTL3_WT_vs_EV_F01.16973.16973.2 0.156 22-Sep -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 1.5 4103 16973 2 1306.76906 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3387.9 - 889536 - - - 0.5969 - 1.359 0.104 - 111.2 2 2 0 0.0008 12 0 0 0 4.47E+07 2.99E+07 - - - 0.4815 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.16974.16974.2 0.0344 18-Oct R.LLLNNDNLLR[166.11].E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1206.696 1.42 4104 16974 2 1206.69639 604.3553 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3388.1 - 846196 - - - 0.3307 - 1.936 0.267 - 297.5 1 2 0 0.0004 10 0 0 0 2.47E+08 1.74E+08 - - - 2.8569 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.16975.16975.2 0.0957 18-Oct K.IEDMAVSLIR[166.11].E sp|Q15776|ZKSC8_HUMAN 1 1155.6197 0.62 4105 16975 2 1155.621325 578.8171 Zinc finger protein with KRAB and SCAN domains 8 OS=Homo sapiens OX=9606 GN=ZKSCAN8 PE=1 SV=2 4.37 3388.2 - 650658 - - - 1.3932 - 1.18 0.276 - 164.1 1 2 0 0.0016 10 0 0 0 6.31E+06 1.01E+07 - - - 1.541 0.9502 230117_WJC_METTL3_WT_vs_EV_F01.16978.16978.2 11 14-Jun K.YVVGLIIK.T "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 903.5793 1.36 4106 16978 2 903.578911 452.7969 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3388.6 - 584077 - - - -0.4748 - 0.964 0.121 - 101.4 1 2 0 -0.0004 8 0 0 0 6.27E+07 4.60E+07 - - - -0.176 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.16980.16980.2 0.00189 18-Sep R.LLLNNDNLLR.E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1196.6877 1.5 4108 16980 2 1196.68854 599.3511 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3388.8 - 181282 - - - 0.6844 - 2.005 0.413 - 230.5 1 2 0 0.0008 10 0 0 0 4.38E+08 2.92E+08 - - - 4.0329 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.16984.16984.2 0.04 14-Sep R.LELSVLYK.E "sp|Q96FW1|OTUB1_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 5 963.5641 2.25 4110 16984 2 963.565368 482.7893 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 6 3389.3 - 2.39E+06 - - - 1.3326 - 1.9 0.339 - 215.2 1 2 0 0.0013 8 0 0 0 3.28E+07 1.45E+07 - - - 3.4803 1 230117_WJC_METTL3_WT_vs_EV_F01.16985.16985.2 5.12E-05 20-Nov R.FDLALAATEAR.Q sp|Q6PD62|CTR9_HUMAN 1 1176.6139 2.37 4111 16985 2 1176.612606 589.3142 RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1 4.37 3389.4 - 889868 - - - -1.0896 - 2.363 0.442 - 367.6 1 2 0 -0.0013 11 0 0 0 1.02E+07 4.31E+06 - - - 4.6315 0.9849 230117_WJC_METTL3_WT_vs_EV_F01.16986.16986.2 1.34 14-Jul K.LPLDVLGR[166.11].V "sp|Q9UBC2|EP15R_HUMAN,tr|M0R2S2|M0R2S2_HUMAN,tr|M0R165|M0R165_HUMAN" 3 891.5417 2.86 4112 16986 2 891.541159 446.7781 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 5.84 3389.5 - 1.83E+06 - - - -0.6315 - 1.256 0.134 - 158 1 2 0 -0.0006 8 0 0 0 6.70E+07 2.34E+07 - - - 0.718 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.16988.16988.2 0.000124 20-Dec R.FDLALAATEAR[166.11].Q sp|Q6PD62|CTR9_HUMAN 1 1186.6222 2.37 4114 16988 2 1186.623749 594.3184 RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1 4.37 3389.7 - 693304 - - - 1.3408 - 2.423 0.401 - 388 1 2 0 0.0016 11 0 0 0 1.02E+07 4.31E+06 - - - 4.3964 0.9912 230117_WJC_METTL3_WT_vs_EV_F01.16992.16992.2 0.0458 12-Jun K.VLLPFTR.A sp|Q8TEM1|PO210_HUMAN 1 844.5171 2.55 4116 16992 2 844.517804 423.2658 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 9.72 3390.2 - 638073 - - - 0.8644 - 1.309 0.095 - 128 1 2 0 0.0007 7 0 0 0 6.09E+07 2.39E+07 - - - 0.5956 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.16993.16993.2 0.00278 22-Dec K.ALLTPVAIAAGR.K sp|P00390|GSHR_HUMAN 1 1151.7026 3.05 4117 16993 2 1151.704127 576.8586 "Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2" 9.79 3390.4 - 330467 - - - 1.2885 - 2.44 0.375 - 428 1 2 0 0.0015 12 0 0 0 6.08E+07 1.99E+07 - - - 4.1573 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.16996.16996.2 0.564 22-Aug -.MVPPVQVSPLIK[136.11].L sp|P56385|ATP5I_HUMAN 1 1314.7825 1.5 4120 16996 2 1314.782129 658.3985 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3390.7 - 257450 - - - -0.267 - 1.57 0.176 - 112.7 1 2 0 -0.0004 12 0 0 0 4.56E+07 3.04E+07 - - - 1.5277 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17000.17000.2 0.00175 16-Sep K.LFSELPLAK.K "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1016.5906 1.24 4122 17000 2 1016.591379 509.3026 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 6 3391.2 - 6.38E+06 - - - 0.7338 - 1.65 0.406 - 234.9 1 2 0 0.0007 9 0 0 0 1.87E+08 1.51E+08 - - - 3.4883 0.9711 230117_WJC_METTL3_WT_vs_EV_F01.17001.17001.2 0.144 14-Aug R.LFGNILDK.H "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|K7ENW7|K7ENW7_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 7 918.5175 0.29 4123 17001 2 918.51365 460.266 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 5.84 3391.3 - 3.83E+06 - - - -4.1567 - 1.429 0.253 - 124.2 1 2 0 -0.0038 8 0 0 0 2.95E+07 1.03E+08 - - - 1.9851 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.17005.17005.2 0.000208 20-Sep R.LYPEGLAQLAR.A "sp|P61421|VA0D1_HUMAN,tr|J3QL14|J3QL14_HUMAN,tr|F5GYQ1|F5GYQ1_HUMAN,tr|R4GN72|R4GN72_HUMAN" 4 1229.6768 1.24 4127 17005 2 1229.679764 615.8457 V-type proton ATPase subunit d 1 OS=Homo sapiens OX=9606 GN=ATP6V0D1 PE=1 SV=1 6 3391.8 - 910860 - - - 2.3925 - 1.543 0.433 - 285.8 1 2 0 0.0029 11 0 0 0 1.76E+07 1.42E+07 - - - 3.4116 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.17012.17012.2 0.000284 20-Sep R.LYPEGLAQLAR[166.11].A "sp|P61421|VA0D1_HUMAN,tr|J3QL14|J3QL14_HUMAN,tr|F5GYQ1|F5GYQ1_HUMAN,tr|R4GN72|R4GN72_HUMAN" 4 1239.6851 1.24 4132 17012 2 1239.689282 620.8498 V-type proton ATPase subunit d 1 OS=Homo sapiens OX=9606 GN=ATP6V0D1 PE=1 SV=1 6 3392.7 - 1.03E+06 - - - 3.3799 - 1.448 0.421 - 263.6 1 2 0 0.0042 11 0 0 0 1.76E+07 1.42E+07 - - - 3.1506 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17013.17013.2 0.014 18-Nov R.ALEAELAALR[166.11].Q sp|Q16352|AINX_HUMAN 1 1065.6058 5.63 4133 17013 2 1065.606349 533.8102 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.53 3392.7 - 4.54E+06 - - - 0.5349 - 2.081 0.253 - 535.1 1 2 0 0.0006 10 0 0 0 3.54E+08 6.29E+07 - - - 2.9551 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.17019.17019.2 0.00157 16-Jul R.LSPFMADIR.D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1048.5376 0.89 4137 17019 2 1048.540389 525.2761 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.84 3393.4 - 1.79E+06 - - - 2.7057 - 1.489 0.406 - 152.6 1 2 0 0.0028 9 0 0 0 4.08E+07 4.59E+07 - - - 3.1906 0.9904 230117_WJC_METTL3_WT_vs_EV_F01.17020.17020.2 0.0421 14-Jun R.LMGDYLLR.G "sp|O60232|ZNRD2_HUMAN,tr|H0YEK1|H0YEK1_HUMAN,tr|E9PK41|E9PK41_HUMAN,tr|H0YEB6|H0YEB6_HUMAN" 4 979.5161 2.17 4138 17020 2 979.51821 490.7653 Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1 5.84 3393.5 - 764302 - - - 2.1664 - 1.091 0.178 - 88.6 1 2 0 0.0021 8 0 0 0 3.75E+07 1.73E+07 - - - 0.6177 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.17021.17021.2 0.253 12-Aug R.LLQLWEK[136.11].N "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 936.5524 1.32 4139 17021 2 936.554792 469.2835 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 6 3393.6 - 2.35E+06 - - - 2.5508 - 1.632 0.232 - 172.6 1 2 0 0.0024 7 0 0 0 9.38E+07 7.11E+07 - - - 2.3058 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.17028.17028.2 0.0125 14-Sep K.MFAEIMMK[136.11].L "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1007.4734 0.97 4144 17028 2 1007.477402 504.744 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 5.75 3394.4 - 1.33E+06 - - - 4.0051 - 1.589 0.307 - 185.2 1 2 0 0.004 8 0 0 0 2.14E+07 2.20E+07 - - - 2.7039 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.17037.17037.2 0.00342 16-Aug K.LFSELPLAK[136.11].K "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1024.6048 1.27 4151 17037 2 1024.607595 513.3097 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 6 3395.5 - 6.48E+06 - - - 2.6957 - 1.464 0.389 - 150.7 1 2 0 0.0028 9 0 0 0 1.86E+08 1.46E+08 - - - 3.016 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.17039.17039.2 0.000119 18-Aug R.LLYEALVDC[160.03]K.K "sp|Q7L2H7|EIF3M_HUMAN,tr|J3KNJ2|J3KNJ2_HUMAN,tr|E9PRY0|E9PRY0_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 4 1222.6268 1.22 4153 17039 2 1222.633865 612.3207 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 4.37 3395.7 - 238254 - - - 5.8104 - 1.782 0.475 - 150.5 1 2 0 0.0071 10 0 0 0 9.39E+06 7.68E+06 - - - 4.1598 1 230117_WJC_METTL3_WT_vs_EV_F01.17040.17040.3 2.42E-07 17/64 K.MLQAPESVLAEHYQDLR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 2008.9916 0.96 4154 17040 3 2008.994188 670.6711 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3395.8 - 210338 - - - 1.2977 - 2.617 0.573 - 185.5 1 2 0 0.0026 17 0 0 0 4.70E+06 4.91E+06 - - - 7.358 0.9946 230117_WJC_METTL3_WT_vs_EV_F01.17045.17045.2 0.583 12-Jul R.IQLIFER.A "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 917.5335 0.81 4157 17045 2 917.536492 459.774 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 3396.4 - 6.93E+06 - - - 3.3132 - 1.534 0.156 - 131.5 1 2 0 0.003 7 0 0 0 6.02E+07 7.40E+07 - - - 1.548 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.17046.17046.2 0.000622 16-Oct R.VSLLC[160.03]PLGK.M sp|O75925|PIAS1_HUMAN 1 985.563 1.04 4158 17046 2 985.568895 493.7888 E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=9606 GN=PIAS1 PE=1 SV=2 8.19 3396.5 - 1.63E+06 - - - 5.9428 - 2.122 0.431 - 308.5 1 2 0 0.0059 9 0 0 0 1.84E+07 1.77E+07 - - - 4.3991 0.9409 230117_WJC_METTL3_WT_vs_EV_F01.17047.17047.2 0.00913 22-May R.IINEPTAAAIAY.G "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 16 1245.6605 - 4159 17047 2 1245.663409 623.8375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4 3396.6 - 1.61E+06 - - - 2.3321 - 1.484 0.386 - 61.5 1 1 0 0.0029 12 0 0 0 - - - - - 2.9297 0.9788 230117_WJC_METTL3_WT_vs_EV_F01.17048.17048.2 0.57 14-Jun K.GLLTPIIK[136.11].D "sp|O00330|ODPX_HUMAN,tr|H0YD97|H0YD97_HUMAN" 2 861.5779 1.66 4160 17048 2 861.581464 431.7962 "Pyruvate dehydrogenase protein X component, mitochondrial OS=Homo sapiens OX=9606 GN=PDHX PE=1 SV=3" 8.75 3396.7 - 1.46E+06 - - - 4.1482 - 1.173 0.187 - 76.3 1 2 0 0.0036 8 0 0 0 3.09E+07 1.86E+07 - - - 0.9023 1 230117_WJC_METTL3_WT_vs_EV_F01.17049.17049.2 1.14E-06 24-Sep R.ILGVGPDDPDLVR.A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1364.73 1.99 4161 17049 2 1364.733042 683.3723 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3396.8 - 396198 - - - 2.2437 - 2.115 0.526 - 236.6 1 2 0 0.0031 13 0 0 0 8.47E+06 4.25E+06 - - - 4.8475 0.9901 230117_WJC_METTL3_WT_vs_EV_F01.17051.17051.2 1.72 14-Jul R.YIYYLITK.K "sp|Q9Y530|OARD1_HUMAN,tr|C9JXC3|C9JXC3_HUMAN,tr|C9JNE2|C9JNE2_HUMAN" 3 1075.5954 2.2 4163 17051 2 1075.599215 538.805 ADP-ribose glycohydrolase OARD1 OS=Homo sapiens OX=9606 GN=OARD1 PE=1 SV=2 8.43 3397.1 - 332484 - - - 3.5617 - 1.205 0.214 - 106 1 2 0 0.0038 8 0 0 0 4.79E+06 2.17E+06 - - - 1.1828 1 230117_WJC_METTL3_WT_vs_EV_F01.17052.17052.2 3.91E-05 24-Oct R.ILGVGPDDPDLVR[166.11].A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1374.7383 1.99 4164 17052 2 1374.741148 688.3764 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3397.2 - 290665 - - - 2.108 - 2.133 0.506 - 293.3 1 2 0 0.0029 13 0 0 0 8.47E+06 4.25E+06 - - - 4.7216 1 230117_WJC_METTL3_WT_vs_EV_F01.17054.17054.2 7.78E-05 18-Sep K.VFEVMLATDR.S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1179.5958 1.71 4166 17054 2 1179.590607 590.8052 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3397.5 - 223813 - - - -4.3981 - 2.123 0.51 - 304.8 1 2 0 -0.0052 10 0 0 0 3.27E+07 1.91E+07 - - - 4.9076 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.17060.17060.2 0.00425 16-Jul R.LVSLYFDTK[136.11].R "sp|O00231|PSD11_HUMAN,tr|J3QRY4|J3QRY4_HUMAN,tr|J3KSW3|J3KSW3_HUMAN" 3 1092.5947 1.66 4170 17060 2 1092.597572 547.3046 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 5.83 3398.2 - 2.34E+06 - - - 2.6634 - 1.624 0.142 - 132.9 1 2 0 0.0029 9 0 0 0 6.96E+07 4.20E+07 - - - 1.4917 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17062.17062.2 0.00207 18-Nov K.VTDAIVLLDR.E "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1113.6394 3.07 4172 17062 2 1113.641164 557.827 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.21 3398.4 - 1.32E+06 - - - 1.6073 - 2.199 0.389 - 268.1 1 2 0 0.0018 10 0 0 0 2.46E+08 8.02E+07 - - - 4.1131 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17063.17063.2 8.47E-06 16-Sep R.ELLTEFGYK[136.11].G sp|P49411|EFTU_HUMAN 1 1106.5739 2.53 4173 17063 2 1106.575741 554.2942 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.53 3398.5 - 946762 - - - 1.6393 - 1.855 0.479 - 202.4 1 2 0 0.0018 9 0 0 0 5.78E+07 2.29E+07 - - - 4.3659 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17064.17064.2 0.00256 20-Oct K.IILEAALQAAK.S sp|Q08378|GOGA3_HUMAN 1 1139.6914 0.95 4174 17064 2 1139.693477 570.853 Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2 6 3398.6 - 580315 - - - 1.8136 - 1.684 0.322 - 175.1 1 2 0 0.0021 11 0 0 0 6.97E+06 7.34E+06 - - - 2.8285 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17066.17066.2 0.00104 18-Nov K.VFEVMLATDR[166.11].S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1189.6041 1.71 4176 17066 2 1189.605383 595.8093 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3398.9 - 487360 - - - 1.1079 - 2.218 0.423 - 491.5 1 2 0 0.0013 10 0 0 0 3.26E+07 1.91E+07 - - - 4.3884 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.17071.17071.2 0.0332 12-Jul R.VPFSLLR[166.11].G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 840.5097 0.99 4179 17071 2 840.51056 421.2621 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3399.6 - 1.74E+06 - - - 1.0303 - 1.269 0.188 - 212.5 1 2 0 0.0009 7 0 0 0 9.55E+07 9.69E+07 - - - 1.1841 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.17073.17073.2 0.0372 12-Jul R.VPFSLLR.G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 830.5014 0.98 4181 17073 2 830.504008 416.258 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3399.8 - 1.84E+06 - - - 3.1114 - 1.436 0.261 - 212.1 1 2 0 0.0026 7 0 0 0 9.42E+07 9.57E+07 - - - 2.1145 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17076.17076.2 0.00401 14-Sep K.VDLVLLGK[136.11].Q sp|P38117|ETFB_HUMAN 1 863.5572 2.25 4182 17076 2 863.558042 432.7859 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3400.2 - 1.25E+06 - - - 1.0283 - 1.967 0.445 - 261.8 1 2 0 0.0009 8 0 0 0 2.30E+08 1.02E+08 - - - 4.3678 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17077.17077.2 0.318 16-Sep K.VGGLLAFAK.R "sp|P28340|DPOD1_HUMAN,tr|M0R3H8|M0R3H8_HUMAN,tr|M0QXQ2|M0QXQ2_HUMAN,tr|M0QXE6|M0QXE6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 874.5276 0.99 4183 17077 2 874.529299 438.2711 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.72 3400.3 - 691866 - - - 1.8982 - 1.85 0.271 - 207.7 1 2 0 0.0017 9 0 0 0 2.25E+07 2.27E+07 - - - 2.8218 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.17087.17087.2 0.000191 18-Nov R.LGLSTLGELK.Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1029.607 2.55 4191 17087 2 1029.610214 515.8108 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3401.5 - 1.91E+06 - - - 3.1109 - 2.299 0.351 - 265.6 1 2 0 0.0032 10 0 0 0 5.05E+08 1.98E+08 - - - 3.9562 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.17088.17088.2 0.0196 14-Jun R.VLFLSTVR.T "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 933.5648 1.93 4192 17088 2 933.566256 467.7897 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 9.72 3401.6 - 2.38E+06 - - - 1.61 - 1.58 0.307 - 99.9 2 2 0 0.0015 8 0 0 0 6.13E+07 3.18E+07 - - - 2.5531 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17089.17089.2 0.000508 14-Aug K.MFGMVLEK[136.11].L sp|P55060|XPO2_HUMAN 1 961.4856 2.31 4193 17089 2 961.48745 481.7501 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.75 3401.7 - 988192 - - - 1.8763 - 1.447 0.36 - 179.2 1 2 0 0.0018 8 0 0 0 7.89E+07 3.41E+07 - - - 2.8138 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.17094.17094.2 0.00151 18-Jul R.LLYEALVDC[160.03]K[136.11].K "sp|Q7L2H7|EIF3M_HUMAN,tr|J3KNJ2|J3KNJ2_HUMAN,tr|E9PRY0|E9PRY0_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 4 1230.641 1.45 4196 17094 2 1230.640495 616.3278 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 4.37 3402.3 - 283955 - - - -0.3787 - 1.566 0.33 - 109.7 1 2 0 -0.0005 10 0 0 0 8.70E+06 6.00E+06 - - - 2.7302 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17095.17095.2 0.00357 18-Nov R.LGLSTLGELK[136.11].Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1037.6212 2.55 4197 17095 2 1037.623385 519.8179 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3402.4 - 2.86E+06 - - - 2.0952 - 2.151 0.425 - 212.6 1 2 0 0.0022 10 0 0 0 5.05E+08 1.98E+08 - - - 4.3173 0.9594 230117_WJC_METTL3_WT_vs_EV_F01.17096.17096.2 0.134 14-May R.VLFLSTVR[166.11].T "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 943.573 1.92 4198 17096 2 943.575578 472.7938 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 9.72 3402.5 - 1.58E+06 - - - 2.7078 - 1.33 0.061 - 61.9 16 2 0 0.0026 8 0 0 0 6.13E+07 3.19E+07 - - - -0.1871 0.9922 230117_WJC_METTL3_WT_vs_EV_F01.17099.17099.2 0.0411 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 8.33 4200 17099 2 1235.767316 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3402.8 - 1.05E+06 - - - 5.7924 - 1.992 0.266 - 151.6 1 2 0 0.0072 11 0 0 0 3.64E+07 4.36E+06 - - - 2.8677 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.17101.17101.2 0.0189 14-Aug K.AGPIWDLR.L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 926.4974 0.94 4201 17101 2 926.499615 464.256 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3403.1 - 1.31E+06 - - - 2.3896 - 1.522 0.295 - 285.7 1 2 0 0.0022 8 0 0 0 5.28E+08 5.62E+08 - - - 2.486 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.17102.17102.2 0.00116 16-Sep R.WGEPEPFLR.L "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 5 1129.5556 2.26 4202 17102 2 1129.556863 565.7851 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.53 3403.2 - 640910 - - - 1.0792 - 1.643 0.402 - 205.5 1 2 0 0.0012 9 0 0 0 1.46E+07 6.48E+06 - - - 3.4463 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17104.17104.2 0.00295 14-Sep K.VDLVLLGK.Q sp|P38117|ETFB_HUMAN 1 855.543 1.76 4204 17104 2 855.545606 428.7788 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3403.3 - 6.97E+06 - - - 3.0998 - 1.956 0.378 - 320.3 1 2 0 0.0027 8 0 0 0 1.49E+08 8.42E+07 - - - 3.8555 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.17108.17108.2 0.0469 22-Aug R.AAVLFATDIAAR.G "sp|Q13206|DDX10_HUMAN,tr|A0A3B3ISR7|A0A3B3ISR7_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 3 1217.6768 0.49 4208 17108 2 1217.677003 609.8457 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 5.88 3403.8 - 169529 - - - 0.1486 - 1.727 0.201 - 133.2 1 2 0 0.0002 12 0 0 0 3.33E+06 6.73E+06 - - - 1.9632 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.17111.17111.2 0.028 14-Jul K.AGPIWDLR[166.11].L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 936.5057 0.94 4209 17111 2 936.507536 469.2601 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3404.2 - 3.61E+06 - - - 1.9914 - 1.29 0.327 - 246.7 1 2 0 0.0019 8 0 0 0 5.28E+08 5.62E+08 - - - 2.2236 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17112.17112.2 0.000542 14-Aug K.MFGMVLEK.L sp|P55060|XPO2_HUMAN 1 953.4714 2.38 4210 17112 2 953.473699 477.743 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.75 3404.2 - 1.61E+06 - - - 2.3629 - 1.412 0.461 - 232.3 1 2 0 0.0023 8 0 0 0 8.83E+07 3.70E+07 - - - 3.4858 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.17115.17115.2 0.00424 16-Sep R.FAVGIVIGR[166.11].N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 940.5734 1.46 4213 17115 2 940.575939 471.294 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3404.4 - 1.99E+06 - - - 2.7451 - 1.72 0.33 - 297.7 1 2 0 0.0026 9 0 0 0 4.87E+08 3.35E+08 - - - 3.0465 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.17117.17117.2 5.29E-05 20-Aug R.IDGLAALSMDR.T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1160.586 1.77 4215 17117 2 1160.584168 581.3003 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3404.6 - 799999 - - - -1.5423 - 2.031 0.413 - 158.9 1 2 0 -0.0018 11 0 0 0 2.77E+07 1.56E+07 - - - 4.0076 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.17119.17119.2 0.000896 20-Oct R.IDGLAALSMDR[166.11].T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1170.5942 1.74 4217 17119 2 1170.598205 586.3044 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3404.7 - 449773 - - - 3.3974 - 1.907 0.393 - 243.1 1 2 0 0.004 11 0 0 0 2.53E+07 1.45E+07 - - - 3.6888 0.9937 230117_WJC_METTL3_WT_vs_EV_F01.17137.17137.2 0.00832 13/22 R.AAVLFATDIAAR[166.11].G "sp|Q13206|DDX10_HUMAN,tr|A0A3B3ISR7|A0A3B3ISR7_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 3 1227.6851 0.52 4228 17137 2 1227.692341 614.8498 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 5.88 3407 - 467125 - - - 5.9046 - 2.107 0.305 - 340 1 2 0 0.0072 12 0 0 0 3.52E+06 6.73E+06 - - - 3.2524 1 230117_WJC_METTL3_WT_vs_EV_F01.17138.17138.2 2.24E-06 22-Oct K.VLQGDLVMNVYR.D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1405.7388 1.66 4229 17138 2 1405.742598 703.8767 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3407.2 - 235253 - - - 2.7224 - 1.936 0.518 - 279.9 1 2 0 0.0038 12 0 0 0 3.52E+06 2.13E+06 - - - 4.604 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.17145.17145.2 0.047 12-Jun R.YGDFFIR.Q "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|H0Y7E6|H0Y7E6_HUMAN,tr|B0QY90|B0QY90_HUMAN" 4 916.4443 0.62 4234 17145 2 916.446351 459.2294 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 5.84 3407.9 - 1.81E+06 - - - 2.2347 - 1.402 0.374 - 104.9 1 2 0 0.002 7 0 0 0 5.75E+07 9.27E+07 - - - 2.8734 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.17149.17149.2 0.00011 22-Oct K.VLQGDLVMNVYR[166.11].D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1415.747 1.66 4238 17149 2 1415.75485 708.8808 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3408.4 - 115687 - - - 5.5158 - 2.017 0.377 - 150.2 1 2 0 0.0078 12 0 0 0 3.52E+06 2.13E+06 - - - 3.6691 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.17154.17154.2 0.462 18-Aug R.LINLVGESLR[166.11].L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1122.6636 3.84 4241 17154 2 1122.666335 562.3391 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6 3408.9 - 3.82E+06 - - - 2.4103 - 1.861 0.276 - 214.6 1 2 0 0.0027 10 0 0 0 3.58E+08 9.33E+07 - - - 2.8124 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.17157.17157.2 0.0462 12-Jul R.DGFGFIK.C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 782.3963 1.85 4242 17157 2 782.397096 392.2054 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3409.3 - 4.34E+06 - - - 1.0302 - 1.07 0.265 - 193.4 1 2 0 0.0008 7 0 0 0 7.83E+07 4.24E+07 - - - 1.2124 0.99 230117_WJC_METTL3_WT_vs_EV_F01.17163.17163.2 0.168 12-Apr R.DGFGFIK[136.11].C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 790.4105 1.99 4246 17163 2 790.411122 396.2125 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3410.1 - 1.11E+06 - - - 0.7996 - 1.013 0.213 - 69.1 2 2 0 0.0006 7 0 0 0 7.79E+07 3.91E+07 - - - 0.5205 0.9951 230117_WJC_METTL3_WT_vs_EV_F01.17166.17166.2 0.602 12-Aug R.ITLDLIR.V sp|Q8N5C6|SRBD1_HUMAN 1 842.5226 0.87 4249 17166 2 842.523105 422.2686 S1 RNA-binding domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SRBD1 PE=1 SV=2 5.84 3410.4 - 892391 - - - 0.6552 - 1.598 0.074 - 191.7 1 2 0 0.0006 7 0 0 0 3.73E+07 4.28E+07 - - - 1.0727 0.9494 230117_WJC_METTL3_WT_vs_EV_F01.17169.17169.2 0.0646 14-Sep K.FLSLPEVR.Q "sp|Q9H3G5|CPVL_HUMAN,tr|H7C0X5|H7C0X5_HUMAN" 2 959.544 3.22 4252 17169 2 959.55206 480.7793 Probable serine carboxypeptidase CPVL OS=Homo sapiens OX=9606 GN=CPVL PE=1 SV=2 6 3410.8 - 507406 - - - 8.3821 - 1.91 0.176 - 211 1 2 0 0.008 8 0 0 0 1.01E+08 3.12E+07 - - - 2.29 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.17177.17177.2 0.382 16-Aug K.AILVVFANK.Q "sp|P40616|ARL1_HUMAN,tr|B4DZG7|B4DZG7_HUMAN,tr|F8VYN9|F8VYN9_HUMAN" 3 973.5961 0.36 4258 17177 2 973.597715 487.8053 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 8.8 3411.7 - 8.21E+06 - - - 1.7071 - 1.822 0.195 - 218.2 1 2 0 0.0017 9 0 0 0 1.13E+08 3.10E+08 - - - 2.2164 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17178.17178.2 0.0259 14-Jul R.ITVLEALR.H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 913.5597 1.25 4259 17178 2 913.561176 457.7871 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3411.7 - 5.99E+06 - - - 1.6518 - 1.737 0.285 - 190.1 1 2 0 0.0015 8 0 0 0 1.67E+08 1.34E+08 - - - 2.8108 0.9785 230117_WJC_METTL3_WT_vs_EV_F01.17180.17180.2 0.00285 16-Sep F.VLVLYDEIK.K "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 3 1090.6274 0.19 4261 17180 2 1090.62916 546.321 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 4.37 3411.9 - 1.10E+06 - - - 1.6027 - 2 0.448 - 207.6 1 1 0 0.0017 9 0 0 0 2.20E+07 1.15E+08 - - - 4.3547 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.17182.17182.2 0.000379 18-Jul R.LVLSTFSNIR.E sp|Q8WVV4|POF1B_HUMAN 1 1148.6554 999 4263 17182 2 1148.660251 575.335 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 9.75 3412 - 981909 - - - 4.2589 - 1.686 0.459 - 129.3 1 2 0 0.0049 10 0 0 0 1.35E+07 0.00E+00 - - - 3.8877 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.17185.17185.2 0.0133 14-Aug K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 0.97 4265 17185 2 988.572107 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3412.3 - 2.00E+07 - - - 1.5588 - 1.603 0.357 - 331 1 2 0 0.0015 8 0 0 0 5.86E+08 6.06E+08 - - - 3.1005 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.17188.17188.2 0.000647 20-Dec K.ALADVATVLGR.A "sp|Q92542|NICA_HUMAN,tr|H0Y6T7|H0Y6T7_HUMAN" 2 1084.6241 2.48 4268 17188 2 1084.622957 543.3193 Nicastrin OS=Homo sapiens OX=9606 GN=NCSTN PE=1 SV=2 5.88 3412.5 - 1.55E+06 - - - -1.0151 - 2.137 0.226 - 351 1 2 0 -0.0011 11 0 0 0 1.28E+07 5.15E+06 - - - 2.7643 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.17194.17194.2 0.000147 18-Oct R.FFNYVPSGIR[166.11].C "sp|Q969X6|UTP4_HUMAN,tr|H3BPD7|H3BPD7_HUMAN" 2 1208.6218 1.37 4272 17194 2 1208.623683 605.3182 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 8.75 3413.3 - 1.84E+06 - - - 1.5878 - 1.681 0.421 - 253.8 1 2 0 0.0019 10 0 0 0 1.63E+07 1.19E+07 - - - 3.5997 0.9901 230117_WJC_METTL3_WT_vs_EV_F01.17195.17195.2 0.316 16-Aug R.GLVGEIIK[136.11]R[166.11].F "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1001.6352 1.85 4273 17195 2 1001.636491 501.8249 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3413.3 - 1.33E+07 - - - 1.2539 - 1.497 0.037 - 191 1 2 0 0.0013 9 0 0 0 3.26E+08 1.77E+08 - - - 0.4811 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.17196.17196.2 0.0288 14-Oct K.AGISFIIK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 847.5167 0.89 4274 17196 2 847.51829 424.7656 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.8 3413.4 - 825978 - - - 1.8289 - 1.597 0.153 - 193.3 1 2 0 0.0015 8 0 0 0 1.85E+09 2.09E+09 - - - 1.5824 0.9891 230117_WJC_METTL3_WT_vs_EV_F01.17197.17197.2 4.07 14-Aug R.LLLAALGR[166.11].R "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 835.5519 1.27 4275 17197 2 835.552382 418.7832 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 9.75 3413.5 - 502334 - - - 0.5852 - 1.406 0.059 - 181.9 1 2 0 0.0005 8 0 0 0 5.43E+07 4.29E+07 - - - 0.5043 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.17202.17202.2 0.0453 18-Oct R.LLDYVPIGPR.F "sp|P46459|NSF_HUMAN,tr|K7EQD6|K7EQD6_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 4 1141.6495 1.58 4278 17202 2 1141.653706 571.832 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.84 3414.1 - 568799 - - - 3.6447 - 1.886 0.271 - 254.6 1 2 0 0.0042 10 0 0 0 4.40E+07 2.79E+07 - - - 2.8123 0.9958 230117_WJC_METTL3_WT_vs_EV_F01.17203.17203.2 0.0541 16-Jul R.VLIFSQMTR[166.11].V "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 1103.6037 0.92 4279 17203 2 1103.60688 552.8091 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 9.72 3414.2 - 379993 - - - 2.9077 - 1.587 0.158 - 88.8 1 2 0 0.0032 9 0 0 0 2.31E+07 2.51E+07 - - - 1.5431 0.9675 230117_WJC_METTL3_WT_vs_EV_F01.17204.17204.2 0.0125 16-Oct R.LLDLELTSR.F "sp|Q9Y2Q9|RT28_HUMAN,tr|H0YAT2|H0YAT2_HUMAN,tr|E5RK86|E5RK86_HUMAN,tr|E5RGC7|E5RGC7_HUMAN,tr|E5RFH3|E5RFH3_HUMAN" 5 1058.5972 1.27 4280 17204 2 1058.605866 530.3059 "28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1" 4.37 3414.3 - 816513 - - - 8.2099 - 2.048 0.22 - 254.6 1 2 0 0.0087 9 0 0 0 3.75E+07 2.94E+07 - - - 2.7371 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.17208.17208.2 0.0218 14-Jul R.ITVLEALR[166.11].H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 923.5679 1.24 4282 17208 2 923.570393 462.7912 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3414.8 - 6.21E+06 - - - 2.6593 - 1.596 0.308 - 181.4 1 2 0 0.0025 8 0 0 0 1.68E+08 1.35E+08 - - - 2.7251 0.9751 230117_WJC_METTL3_WT_vs_EV_F01.17209.17209.2 0.000136 16-Oct F.ADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 952.5957 5.27 4283 17209 2 952.597814 477.3051 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3414.9 - 1.55E+06 - - - 2.2003 - 1.858 0.483 - 322.2 1 1 0 0.0021 9 0 0 0 5.01E+07 9.51E+06 - - - 4.4 0.988 230117_WJC_METTL3_WT_vs_EV_F01.17210.17210.2 2.59 14-Jun R.EILETLIK.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 957.5746 1.54 4284 17210 2 957.576872 479.7946 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3414.9 - 2.46E+06 - - - 2.3215 - 1.249 0.126 - 101.1 2 2 0 0.0022 8 0 0 0 1.44E+08 9.31E+07 - - - 0.507 0.9714 230117_WJC_METTL3_WT_vs_EV_F01.17211.17211.2 0.0963 18-Aug R.LLDYVPIGPR[166.11].F "sp|P46459|NSF_HUMAN,tr|K7EQD6|K7EQD6_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 4 1151.6578 1.58 4285 17211 2 1151.667182 576.8362 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.84 3415 - 462552 - - - 8.1335 - 1.852 0.285 - 186.6 1 2 0 0.0094 10 0 0 0 4.40E+07 2.79E+07 - - - 2.8633 0.999 230117_WJC_METTL3_WT_vs_EV_F01.17220.17220.2 0.104 14-Aug K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 0.97 4290 17220 2 998.580859 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3416.1 - 6.39E+06 - - - 2.0259 - 1.66 0.267 - 235.7 1 2 0 0.002 8 0 0 0 6.07E+08 6.23E+08 - - - 2.541 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.17223.17223.2 5.14 12-Jun R.EIVWLER.E "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 943.5127 1.54 4293 17223 2 943.514445 472.7636 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 4.53 3416.3 - 1.77E+06 - - - 1.8315 - 1.324 0.185 - 163.4 1 2 0 0.0017 7 0 0 0 6.27E+07 4.06E+07 - - - 1.2961 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.17231.17231.2 0.00246 16-Aug K.SSLNPILFR[166.11].G "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1055.6003 1.33 4299 17231 2 1055.60207 528.8074 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 9.47 3417.3 - 4.20E+06 - - - 1.6768 - 1.752 0.275 - 169.6 1 2 0 0.0018 9 0 0 0 1.31E+08 9.89E+07 - - - 2.6939 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.17232.17232.2 0.742 14-Sep R.IAYFTLPK.T sp|Q92900|RENT1_HUMAN 1 951.543 0.77 4300 17232 2 951.54574 476.7788 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.59 3417.3 - 3.30E+06 - - - 2.9279 - 1.666 0.284 - 249.9 1 2 0 0.0028 8 0 0 0 8.35E+07 1.08E+08 - - - 2.6772 0.9907 230117_WJC_METTL3_WT_vs_EV_F01.17233.17233.2 1.89 14-Jul K.FIIPNVVK.Y "sp|P00338|LDHA_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 3 928.5746 0.9 4301 17233 2 928.575969 465.2946 L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2 8.75 3417.4 - 4.46E+06 - - - 1.4861 - 1.094 0.164 - 162.9 1 2 0 0.0014 8 0 0 0 5.52E+07 6.12E+07 - - - 0.5228 0.999 230117_WJC_METTL3_WT_vs_EV_F01.17235.17235.2 0.0227 12-Jul K.ISFELMR.E "sp|Q9UNE7|CHIP_HUMAN,tr|H3BUD0|H3BUD0_HUMAN,tr|H3BTA3|H3BTA3_HUMAN" 3 894.4633 2.79 4303 17235 2 894.464458 448.2389 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 6 3417.5 - 965560 - - - 1.2678 - 1.405 0.31 - 115.2 1 2 0 0.0011 7 0 0 0 3.14E+07 1.13E+07 - - - 2.4077 0.9393 230117_WJC_METTL3_WT_vs_EV_F01.17236.17236.2 0.984 22-Aug K.LIETFSPTESLR.M sp|A6NGG8|PCARE_HUMAN 1 1391.7296 1.6 4304 17236 2 1391.72517 696.8721 Photoreceptor cilium actin regulator OS=Homo sapiens OX=9606 GN=PCARE PE=1 SV=1 4.53 3417.6 - 237518 - - - -3.2161 - 1.583 0.083 - 66.1 1 2 0 -0.0045 12 0 0 0 1.38E+07 8.65E+06 - - - 0.8612 0.998 230117_WJC_METTL3_WT_vs_EV_F01.17240.17240.2 3.14 14-Sep R.LLLAALGR.R "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 825.5436 1.26 4306 17240 2 825.544203 413.7791 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 9.75 3418.1 - 993414 - - - 0.7026 - 1.688 0.159 - 231 1 2 0 0.0006 8 0 0 0 5.40E+07 4.29E+07 - - - 1.7942 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.17241.17241.2 0.00377 14-Jul K.AVPSWFVR[166.11].V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 970.5264 2.54 4307 17241 2 970.52692 486.2705 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3418.2 - 2.15E+06 - - - 0.5286 - 1.585 0.269 - 203.5 1 2 0 0.0005 8 0 0 0 1.55E+08 6.09E+07 - - - 2.4168 0.996 230117_WJC_METTL3_WT_vs_EV_F01.17244.17244.2 0.509 12-Jun K.VDAFEER.H sp|P51580|TPMT_HUMAN 1 864.3977 1.23 4310 17244 2 864.398018 433.2061 Thiopurine S-methyltransferase OS=Homo sapiens OX=9606 GN=TPMT PE=1 SV=1 4.14 3418.4 - 566243 - - - 0.3135 - 1.159 0.247 - 143.8 1 2 0 0.0003 7 0 0 0 1.04E+07 8.48E+06 - - - 1.3328 0.999 230117_WJC_METTL3_WT_vs_EV_F01.17245.17245.2 0.000146 16-Oct K.LNNLVLFDK[136.11].A sp|P62851|RS25_HUMAN 1 1082.6215 1.05 4311 17245 2 1082.619846 542.318 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3418.5 - 316957 - - - -1.5703 - 2.411 0.38 - 336.2 1 2 0 -0.0017 9 0 0 0 9.15E+08 8.73E+08 - - - 4.3932 0.9699 230117_WJC_METTL3_WT_vs_EV_F01.17246.17246.2 0.394 18-Jul R.FFNYVPSGIR.C "sp|Q969X6|UTP4_HUMAN,tr|H3BPD7|H3BPD7_HUMAN" 2 1198.6135 1.36 4312 17246 2 1198.617558 600.314 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 8.75 3418.6 - 233095 - - - 3.3906 - 1.15 0.116 - 77.6 1 2 0 0.0041 10 0 0 0 1.61E+07 1.19E+07 - - - 0.2866 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.17252.17252.2 0.024 16-Jul R.AGFVPVYLR[166.11].Q "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1030.5839 0.7 4316 17252 2 1030.585237 516.2992 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 8.79 3419.2 - 2.55E+06 - - - 1.276 - 1.361 0.245 - 151.4 1 2 0 0.0013 9 0 0 0 5.33E+07 7.57E+07 - - - 1.7419 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.17253.17253.2 0.00513 18-Sep R.LGGIGQFLAK.A sp|Q08211|DHX9_HUMAN 1 1002.5862 0.84 4317 17253 2 1002.589239 502.3004 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3419.3 - 2.31E+06 - - - 3.0152 - 1.928 0.28 - 171.5 1 2 0 0.003 10 0 0 0 3.55E+08 4.23E+08 - - - 2.9406 0.9951 230117_WJC_METTL3_WT_vs_EV_F01.17254.17254.2 0.672 14-Aug R.IASFLQLK.N "sp|P42694|HELZ_HUMAN,tr|J3KT20|J3KT20_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 4 918.5539 0.57 4318 17254 2 918.55714 460.2842 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.75 3419.3 - 2.19E+06 - - - 3.5774 - 1.629 0.172 - 130.2 1 2 0 0.0033 8 0 0 0 3.91E+07 6.84E+07 - - - 1.782 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.17255.17255.2 0.0563 14-Sep K.TLVLLMGK.E "sp|P07737|PROF1_HUMAN,tr|K7EJ44|K7EJ44_HUMAN" 2 873.5358 0.85 4319 17255 2 873.535677 437.7752 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 8.41 3419.4 - 1.92E+06 - - - -0.0962 - 1.485 0.247 - 331.6 1 2 0 -0.0001 8 0 0 0 5.05E+07 5.93E+07 - - - 2.0579 0.973 230117_WJC_METTL3_WT_vs_EV_F01.17257.17257.2 4.35 12-Aug K.LPLISLR.L "sp|Q96RL7|VP13A_HUMAN,sp|Q6UXB3|LYPD2_HUMAN,sp|Q6DN12|MCTP2_HUMAN,tr|I6L8E2|I6L8E2_HUMAN" 4 810.5327 1.47 4321 17257 2 810.53174 406.2736 Vacuolar protein sorting-associated protein 13A OS=Homo sapiens OX=9606 GN=VPS13A PE=1 SV=2 9.75 3419.6 - 715555 - - - -1.214 - 1.443 0.048 - 203.9 1 2 0 -0.001 7 0 0 0 1.17E+07 8.00E+06 - - - 0.5572 0.9411 230117_WJC_METTL3_WT_vs_EV_F01.17259.17259.2 0.397 20-Aug K.NILAAASPYIR[166.11].T "sp|Q9H2C0|GAN_HUMAN,tr|A0A3B3ITY2|A0A3B3ITY2_HUMAN,tr|A0A0S2Z5G5|A0A0S2Z5G5_HUMAN" 3 1197.6745 1.06 4323 17259 2 1197.681344 599.8445 Gigaxonin OS=Homo sapiens OX=9606 GN=GAN PE=1 SV=1 8.75 3419.9 - 397481 - - - 5.691 - 1.533 0.095 - 105 1 2 0 0.0068 11 0 0 0 2.43E+06 2.31E+06 - - - 0.8963 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.17261.17261.2 4.29 14-Jul R.EILETLIK[136.11].G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 965.5888 1.54 4324 17261 2 965.589608 483.8017 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3420.1 - 7.34E+06 - - - 0.786 - 1.66 0.131 - 185.6 1 2 0 0.0008 8 0 0 0 1.44E+08 9.31E+07 - - - 1.5369 0.998 230117_WJC_METTL3_WT_vs_EV_F01.17264.17264.2 0.176 14-Jun R.VIPLPQWK.A sp|Q96ES7|SGF29_HUMAN 1 979.5855 1.79 4326 17264 2 979.586347 490.8 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 8.72 3420.4 - 2.12E+06 - - - 0.8769 - 1.169 0.304 - 124.6 1 2 0 0.0009 8 0 0 0 3.16E+07 1.76E+07 - - - 1.757 0.998 230117_WJC_METTL3_WT_vs_EV_F01.17271.17271.2 0.0152 14-Jul K.AVPSWFVR.V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 960.5181 2.54 4331 17271 2 960.518604 481.2663 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3421.1 - 6.54E+06 - - - 0.4862 - 1.309 0.27 - 139 1 2 0 0.0005 8 0 0 0 1.57E+08 6.18E+07 - - - 1.8472 0.9653 230117_WJC_METTL3_WT_vs_EV_F01.17272.17272.2 0.105 16-Jul K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 1273.68 4332 17272 2 1014.541273 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3421.1 - 7.85E+06 - - - 6.602 - 1.588 0.198 - 109.2 1 2 0 0.0067 9 0 0 0 2.95E+08 2.32E+05 - - - 1.8393 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.17279.17279.2 0.000191 16-Aug R.AGFVPVYLR.Q "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1020.5757 0.71 4338 17279 2 1020.576974 511.2951 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 8.79 3422 - 3.48E+06 - - - 1.2953 - 1.519 0.428 - 206.2 1 2 0 0.0013 9 0 0 0 5.34E+07 7.57E+07 - - - 3.4112 0.9562 230117_WJC_METTL3_WT_vs_EV_F01.17286.17286.2 0.00444 20-Sep R.QLYHLGVVEAY.S sp|Q08211|DHX9_HUMAN 1 1290.6608 - 4345 17286 2 1290.663006 646.3377 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.24 3422.7 - 233973 - - - 1.6798 - 1.572 0.379 - 147.1 1 1 0 0.0022 11 0 0 0 - - - - - 3.0633 0.999 230117_WJC_METTL3_WT_vs_EV_F01.17289.17289.2 0.00406 22-Oct -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 1.42 4346 17289 2 1306.771248 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3423.1 - 160984 - - - 2.2713 - 1.695 0.303 - 209.5 1 2 0 0.003 12 0 0 0 3.51E+07 2.47E+07 - - - 2.6664 0.995 230117_WJC_METTL3_WT_vs_EV_F01.17294.17294.2 0.619 12-Aug K.YLELFQR[166.11].Q "sp|Q9UBQ6|EXTL2_HUMAN,tr|C9JEG3|C9JEG3_HUMAN" 2 977.521 0.95 4351 17294 2 977.520511 489.7678 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 6 3423.7 - 359775 - - - -0.4869 - 1.521 0.154 - 237.4 1 2 0 -0.0005 7 0 0 0 8.94E+06 9.46E+06 - - - 1.5071 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17298.17298.2 0.0211 16-Nov K.LNNLVLFDK.A sp|P62851|RS25_HUMAN 1 1074.6073 1.05 4353 17298 2 1074.608215 538.3109 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3424.3 - 7.23E+07 - - - 0.8087 - 2.398 0.354 - 417.7 1 2 0 0.0009 9 0 0 0 9.15E+08 8.73E+08 - - - 4.1857 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17300.17300.2 0.000716 14-Aug K.MVGFIIGR.G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 891.5 1.4 4355 17300 2 891.499987 446.7573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3424.4 - 3.68E+06 - - - -0.0639 - 1.487 0.416 - 223 1 2 0 -0.0001 8 0 0 0 5.01E+08 3.59E+08 - - - 3.3102 0.9903 230117_WJC_METTL3_WT_vs_EV_F01.17301.17301.2 0.808 12-Jul K.GLLDDLR.N sp|Q07065|CKAP4_HUMAN 1 800.4392 1.36 4356 17301 2 800.440213 401.2269 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.21 3424.6 - 984589 - - - 1.2431 - 1.194 0.121 - 175.8 1 2 0 0.001 7 0 0 0 3.23E+07 2.38E+07 - - - 0.4962 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.17302.17302.2 0.0106 14-Sep R.TFLVPEIK.S sp|Q9P1Y5|CAMP3_HUMAN 1 945.5535 1.09 4357 17302 2 945.554375 473.784 Calmodulin-regulated spectrin-associated protein 3 OS=Homo sapiens OX=9606 GN=CAMSAP3 PE=1 SV=2 5.66 3424.7 - 844457 - - - 0.9053 - 1.465 0.317 - 283 1 2 0 0.0009 8 0 0 0 1.31E+07 1.21E+07 - - - 2.5338 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17305.17305.2 0.000287 18-Aug R.LGGIGQFLAK[136.11].A sp|Q08211|DHX9_HUMAN 1 1010.6004 0.84 4359 17305 2 1010.602531 506.3075 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3425 - 4.83E+07 - - - 2.0928 - 1.791 0.374 - 145.5 1 2 0 0.0021 10 0 0 0 3.55E+08 4.21E+08 - - - 3.4294 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17307.17307.2 0.0768 14-Jul K.LFIGMISK.K "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 907.5201 1.49 4360 17307 2 907.521187 454.7673 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.75 3425.3 - 1.00E+06 - - - 1.1856 - 1.484 0.351 - 124.3 1 2 0 0.0011 8 0 0 0 9.54E+06 6.41E+06 - - - 2.8237 0.9904 230117_WJC_METTL3_WT_vs_EV_F01.17311.17311.2 0.627 18-May K.VALDLDPYVK.K sp|O95295|SNAPN_HUMAN 1 1131.6176 1.78 4364 17311 2 1131.618791 566.8161 SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN PE=1 SV=1 4.21 3425.5 - 1.57E+06 - - - 1.0737 - 1.104 0.162 - 68 1 2 0 0.0012 10 0 0 0 2.46E+07 1.38E+07 - - - 0.5133 0.9962 230117_WJC_METTL3_WT_vs_EV_F01.17313.17313.2 0.472 18-Jun K.VALDLDPYVK[136.11].K sp|O95295|SNAPN_HUMAN 1 1139.6318 1.78 4366 17313 2 1139.633588 570.8232 SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN PE=1 SV=1 4.21 3425.7 - 950382 - - - 1.59 - 1.204 0.223 - 69.7 1 2 0 0.0018 10 0 0 0 2.46E+07 1.38E+07 - - - 1.2057 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.17315.17315.2 0.0649 20-Sep K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 2.38 4368 17315 2 1245.771454 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3426 - 577133 - - - 2.429 - 1.761 0.307 - 179.4 1 2 0 0.003 11 0 0 0 3.46E+07 1.45E+07 - - - 2.8384 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.17320.17320.2 0.00455 14-Jul K.LFDFVNAK.K "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 952.5018 0.46 4371 17320 2 952.503385 477.2582 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 5.84 3426.7 - 2.17E+06 - - - 1.6451 - 1.335 0.369 - 103.8 1 2 0 0.0016 8 0 0 0 5.51E+07 1.20E+08 - - - 2.6373 0.9672 230117_WJC_METTL3_WT_vs_EV_F01.17321.17321.2 0.00401 16-Oct D.IPIILVGNK.S "sp|P55040|GEM_HUMAN,sp|Q8IXI2|MIRO1_HUMAN,tr|H7BXZ6|H7BXZ6_HUMAN" 3 965.6274 2.04 4372 17321 2 965.628273 483.821 GTP-binding protein GEM OS=Homo sapiens OX=9606 GN=GEM PE=1 SV=1 8.75 3426.8 - 499153 - - - 0.9527 - 2.089 0.317 - 255.7 1 1 0 0.0009 9 0 0 0 8.57E+06 4.21E+06 - - - 3.5133 0.999 230117_WJC_METTL3_WT_vs_EV_F01.17323.17323.2 2.13 14-Sep K.GWGLLGPR[166.11].N "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 864.4845 1.05 4374 17323 2 864.485479 433.2495 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 9.75 3427 - 770108 - - - 1.0839 - 1.776 0.215 - 344.9 1 2 0 0.0009 8 0 0 0 1.98E+07 1.89E+07 - - - 2.361 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17325.17325.2 0.00012 22-Sep R.IVPGQFLAVDPK.G sp|Q15393|SF3B3_HUMAN 1 1282.7285 1.21 4376 17325 2 1282.730485 642.3715 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3427.3 - 379429 - - - 1.5288 - 1.975 0.478 - 195.1 1 2 0 0.002 12 0 0 0 1.50E+07 1.23E+07 - - - 4.3616 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.17328.17328.2 0.00627 22-Sep R.ILYIVASDPYSR.L "sp|Q9ULT8|HECD1_HUMAN,tr|H0YJD4|H0YJD4_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN,tr|H0YJP0|H0YJP0_HUMAN" 4 1395.7398 3.12 4379 17328 2 1395.741342 698.8772 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 5.83 3427.7 - 143133 - - - 1.0926 - 1.899 0.414 - 311.5 1 2 0 0.0015 12 0 0 0 3.30E+06 1.06E+06 - - - 3.7858 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17336.17336.2 0.301 14-Oct R.IVEVLLMK[136.11].D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 951.5918 0.96 4385 17336 2 951.593561 476.8032 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3428.5 - 5.86E+06 - - - 1.8243 - 2.043 0.277 - 264.4 1 2 0 0.0017 8 0 0 0 2.67E+08 2.79E+08 - - - 3.241 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.17337.17337.2 2.27 16-Sep K.RVLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1037.7073 1.24 4386 17337 2 1037.709369 519.8609 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3428.5 - 3.14E+06 - - - 1.9611 - 1.674 0.245 - 142 1 2 0 0.002 9 0 0 0 1.21E+08 9.71E+07 - - - 2.3405 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.17342.17342.2 0.2 12-Jul R.GFLYFNR[166.11].Q sp|Q10570|CPSF1_HUMAN 1 925.4686 1.58 4391 17342 2 925.47021 463.7416 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3428.8 - 650208 - - - 1.7861 - 1.453 0.184 - 185.9 1 2 0 0.0017 7 0 0 0 9.41E+06 5.94E+06 - - - 1.5834 0.9911 230117_WJC_METTL3_WT_vs_EV_F01.17345.17345.2 0.452 12-Jun K.GLLDDLR[166.11].N sp|Q07065|CKAP4_HUMAN 1 810.4475 1.36 4393 17345 2 810.448314 406.231 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.21 3429.2 - 2.06E+06 - - - 1.0192 - 1.192 0.132 - 154 1 2 0 0.0008 7 0 0 0 3.23E+07 2.38E+07 - - - 0.5722 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.17346.17346.2 0.0513 18-Nov R.LINLVGESLR.L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1112.6554 3.89 4394 17346 2 1112.657333 557.335 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6 3429.3 - 2.41E+06 - - - 1.7741 - 2.415 0.303 - 316.4 1 2 0 0.002 10 0 0 0 3.93E+08 1.01E+08 - - - 3.7394 0.9922 230117_WJC_METTL3_WT_vs_EV_F01.17347.17347.2 0.376 14-Aug R.AYILNLVK.Q sp|P50991|TCPD_HUMAN 1 932.5695 7.61 4395 17347 2 932.572886 467.292 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.63 3429.4 - 1.45E+06 - - - 3.6265 - 1.373 0.191 - 202.9 1 2 0 0.0034 8 0 0 0 1.94E+09 2.55E+08 - - - 1.4067 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17351.17351.2 0.00695 24-Oct K.LLPHQLYGVVPQA.- "sp|P18887|XRCC1_HUMAN,tr|F5H8D7|F5H8D7_HUMAN" 2 1433.8031 - 4399 17351 2 1433.802781 717.9088 DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2 6.74 3430 - 433345 - - - -0.212 - 2.048 0.368 - 210.5 1 2 0 -0.0003 13 0 0 0 - - - - - 3.5988 1 230117_WJC_METTL3_WT_vs_EV_F01.17356.17356.2 0.00419 18-Oct K.VVDLLAPYAK.G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1087.6277 1.67 4402 17356 2 1087.630108 544.8211 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3430.7 - 3.09E+06 - - - 2.1708 - 2.096 0.502 - 357.8 1 2 0 0.0024 10 0 0 0 4.72E+08 2.83E+08 - - - 4.8137 1 230117_WJC_METTL3_WT_vs_EV_F01.17357.17357.2 6.00E-06 18-Oct K.VVDLLAPYAK[136.11].G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1095.6419 1.71 4403 17357 2 1095.644206 548.8282 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3430.7 - 2.17E+06 - - - 2.0618 - 1.982 0.498 - 354.2 1 2 0 0.0023 10 0 0 0 4.89E+08 2.86E+08 - - - 4.6281 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17358.17358.2 0.126 16-Nov K.R[166.11]VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1057.7239 1.24 4404 17358 2 1057.725844 529.8692 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3430.7 - 6.63E+06 - - - 1.8625 - 1.71 0.305 - 223.4 1 2 0 0.002 9 0 0 0 1.21E+08 9.71E+07 - - - 2.8452 0.998 230117_WJC_METTL3_WT_vs_EV_F01.17359.17359.2 0.216 14-Aug K.GWGLLGPR.N "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 854.4763 0.89 4405 17359 2 854.477888 428.2454 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 9.75 3430.8 - 1.51E+06 - - - 1.8912 - 1.668 0.163 - 231.4 1 2 0 0.0016 8 0 0 0 1.74E+07 1.96E+07 - - - 1.7874 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17360.17360.2 0.000694 22-Sep R.IVPGQFLAVDPK[136.11].G sp|Q15393|SF3B3_HUMAN 1 1290.7427 1.24 4406 17360 2 1290.744684 646.3786 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3430.9 - 960212 - - - 1.5185 - 1.766 0.494 - 134.4 1 2 0 0.002 12 0 0 0 1.79E+07 1.45E+07 - - - 4.1855 0.9086 230117_WJC_METTL3_WT_vs_EV_F01.17363.17363.2 0.113 14-Aug R.MYLSLIAK.S sp|Q99959|PKP2_HUMAN 1 937.5307 0.43 4409 17363 2 937.536524 469.7726 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 8.34 3431.1 - 380605 - - - 6.2387 - 1.312 0.13 - 150.4 1 2 0 0.0058 8 0 0 0 5.11E+06 1.18E+07 - - - 0.8183 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.17365.17365.2 0.00608 18-Jul K.VIPYIASQFR.K sp|Q9NU22|MDN1_HUMAN 1 1192.6604 0.35 4411 17365 2 1192.661136 597.3375 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 8.72 3431.4 - 174463 - - - 0.5802 - 1.471 0.306 - 141.5 1 2 0 0.0007 10 0 0 0 1.91E+06 5.50E+06 - - - 2.3782 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17370.17370.2 0.0011 20-Nov R.LYPVLQQSLVR[166.11].A sp|Q5RKV6|EXOS6_HUMAN 1 1324.7742 0.8 4414 17370 2 1324.778076 663.3944 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.75 3432.1 - 1.35E+06 - - - 2.8941 - 1.724 0.402 - 235.5 1 2 0 0.0038 11 0 0 0 1.50E+07 1.88E+07 - - - 3.4824 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17371.17371.2 0.0015 18-Nov -.MLIEDVDALK.S "sp|Q9P2N5|RBM27_HUMAN,tr|U3KPZ7|U3KPZ7_HUMAN" 2 1145.6002 0.69 4415 17371 2 1145.603844 573.8074 RNA-binding protein 27 OS=Homo sapiens OX=9606 GN=RBM27 PE=1 SV=2 4.03 3432.2 - 742386 - - - 3.1713 - 1.948 0.388 - 331.8 1 2 0 0.0036 10 0 0 0 9.70E+06 1.41E+07 - - - 3.7669 1 230117_WJC_METTL3_WT_vs_EV_F01.17373.17373.2 0.000187 13/24 K.LLLGAGAVAYGVR.E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1258.7398 1.37 4417 17373 2 1258.74222 630.3772 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3432.5 - 681990 - - - 1.9567 - 2.451 0.507 - 548.3 1 2 0 0.0025 13 0 0 0 1.86E+08 1.36E+08 - - - 5.0858 1 230117_WJC_METTL3_WT_vs_EV_F01.17377.17377.2 1.35E-05 16/24 K.LLLGAGAVAYGVR[166.11].E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1268.748 1.37 4421 17377 2 1268.750625 635.3813 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3433 - 552162 - - - 2.0477 - 2.844 0.473 - 855.3 1 2 0 0.0026 13 0 0 0 1.86E+08 1.36E+08 - - - 5.2163 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.17378.17378.2 0.391 16-Oct K.SLPSLVPLR[166.11].L "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 990.6101 1.75 4422 17378 2 990.613304 496.3123 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 9.47 3433.1 - 496081 - - - 3.198 - 1.822 0.292 - 241.5 1 2 0 0.0032 9 0 0 0 1.22E+07 6.97E+06 - - - 2.9324 0.9474 230117_WJC_METTL3_WT_vs_EV_F01.17389.17389.2 0.000332 22-Jul R.VINEPTAAALAY.G "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1231.6449 - 4432 17389 2 1231.646897 616.8297 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4 3434.5 - 576105 - - - 1.6596 - 1.59 0.346 - 98.2 1 1 0 0.002 12 0 0 0 - - - - - 2.8161 0.9917 230117_WJC_METTL3_WT_vs_EV_F01.17390.17390.2 3.31 18-Aug R.LASMATLLAR.A sp|Q96P11|NSUN5_HUMAN 1 1045.5954 1.33 4433 17390 2 1045.59803 523.805 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 9.75 3434.6 - 295640 - - - 2.5144 - 1.479 0.096 - 112.5 1 2 0 0.0026 10 0 0 0 1.31E+08 9.89E+07 - - - 0.8417 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.17391.17391.2 0.626 16-Jun R.AFLGQVLVR.R "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1001.6022 0.34 4434 17391 2 1001.604101 501.8084 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 9.79 3434.6 - 2.53E+06 - - - 1.897 - 1.406 0.309 - 98.6 2 2 0 0.0019 9 0 0 0 1.02E+08 2.99E+08 - - - 2.174 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.17393.17393.2 0.0439 16-Sep R.TPLDLAAFK.G "sp|O15084|ANR28_HUMAN,tr|B4DIW9|B4DIW9_HUMAN" 2 974.5437 1.9 4436 17393 2 974.545267 488.2791 Serine\threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5 5.5 3434.8 - 819560 - - - 1.6254 - 1.947 0.283 - 223.1 1 2 0 0.0016 9 0 0 0 1.88E+07 9.94E+06 - - - 3.0584 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17401.17401.2 0.0363 14-Nov R.IVEVLLMK.D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 943.5776 0.96 4443 17401 2 943.579541 472.7961 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3435.7 - 3.82E+07 - - - 2.0306 - 2.192 0.371 - 393.1 1 2 0 0.0019 8 0 0 0 2.67E+08 2.79E+08 - - - 4.1476 0.9797 230117_WJC_METTL3_WT_vs_EV_F01.17403.17403.2 2.12 12-May R.DFYFSVK[136.11].L sp|Q9NY12|GAR1_HUMAN 1 912.4473 0.7 4445 17403 2 912.448179 457.2309 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3435.9 - 4.69E+06 - - - 0.9962 - 1.1 0.09 - 100.5 1 2 0 0.0009 7 0 0 0 8.30E+07 1.19E+08 - - - 0.0075 0.996 230117_WJC_METTL3_WT_vs_EV_F01.17404.17404.2 0.518 14-Aug R.LLNIWQER.S sp|Q9NQG5|RPR1B_HUMAN 1 1070.5873 3.23 4446 17404 2 1070.591064 536.3009 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 6 3435.9 - 3.51E+06 - - - 3.5354 - 1.886 0.135 - 214.4 1 2 0 0.0038 8 0 0 0 1.06E+08 3.29E+07 - - - 1.9504 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.17405.17405.2 0.00721 12-Jun R.DFYFSVK.L sp|Q9NY12|GAR1_HUMAN 1 904.4331 0.71 4447 17405 2 904.435725 453.2238 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3436 - 2.26E+06 - - - 2.9355 - 1.097 0.334 - 154.2 1 2 0 0.0027 7 0 0 0 8.27E+07 1.17E+08 - - - 1.8004 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17408.17408.2 0.0169 16-Oct R.TPLDLAAFK[136.11].G "sp|O15084|ANR28_HUMAN,tr|B4DIW9|B4DIW9_HUMAN" 2 982.5579 2.33 4450 17408 2 982.559859 492.2862 Serine\threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5 5.5 3436.2 - 1.47E+06 - - - 2.0111 - 1.934 0.341 - 333.9 1 2 0 0.002 9 0 0 0 2.45E+07 1.05E+07 - - - 3.4672 0.9969 230117_WJC_METTL3_WT_vs_EV_F01.17410.17410.2 0.305 12-Jul R.VLFSLVK.R "sp|Q14999|CUL7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 2 804.5109 0.59 4452 17410 2 804.512871 403.2627 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 8.72 3436.4 - 1.23E+06 - - - 2.4176 - 1.519 0.163 - 155.8 1 2 0 0.0019 7 0 0 0 5.81E+06 9.91E+06 - - - 1.5689 0.9951 230117_WJC_METTL3_WT_vs_EV_F01.17411.17411.2 0.142 14-Jun K.AITAATLK.F sp|P11277|SPTB1_HUMAN 1 787.4804 0.81 4453 17411 2 787.481194 394.7475 "Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB PE=1 SV=5" 8.8 3436.5 - 1.21E+06 - - - 1.0667 - 1.345 0.144 - 101.1 1 2 0 0.0008 8 0 0 0 9.28E+06 1.14E+07 - - - 0.9982 0.9888 230117_WJC_METTL3_WT_vs_EV_F01.17412.17412.2 0.251 16-Jul K.LESIASVFK.D sp|Q9UKJ3|GPTC8_HUMAN 1 992.5542 0.08 4454 17412 2 992.552644 497.2844 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 6 3436.6 - 1.03E+06 - - - -1.615 - 1.511 0.162 - 87.9 1 2 0 -0.0016 9 0 0 0 5.18E+06 6.12E+07 - - - 1.4312 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17415.17415.2 0.123 20-Jul K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.3 4457 17415 2 1235.761764 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3437 - 633378 - - - 1.2996 - 1.738 0.367 - 144.5 1 2 0 0.0016 11 0 0 0 1.09E+07 8.40E+06 - - - 3.2464 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.17416.17416.2 0.0501 12-Jul R.WLLDNVR[166.11].K "sp|Q14409|GLPK3_HUMAN,sp|P32189|GLPK_HUMAN,tr|H7C2A0|H7C2A0_HUMAN" 3 924.5057 0.59 4458 17416 2 924.508507 463.2601 Glycerol kinase 3 OS=Homo sapiens OX=9606 GN=GK3P PE=2 SV=2 5.84 3437.1 - 630944 - - - 3.0676 - 1.389 0.261 - 131.8 1 2 0 0.0028 7 0 0 0 7.11E+06 1.21E+07 - - - 2.009 1 230117_WJC_METTL3_WT_vs_EV_F01.17418.17418.2 2.03E-05 15/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 3.48 4460 17418 2 1484.909251 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3437.3 - 614093 - - - 0.9199 - 2.49 0.578 - 620.4 1 2 0 0.0014 15 0 0 0 4.99E+07 1.43E+07 - - - 5.5526 0.9897 230117_WJC_METTL3_WT_vs_EV_F01.17420.17420.2 0.00908 24-Sep R.SLLVNPEGPTLMR[166.11].L "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1435.7733 2.24 4462 17420 2 1435.769511 718.8939 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.72 3437.6 - 218586 - - - -2.6077 - 1.846 0.197 - 305.5 1 2 0 -0.0037 13 0 0 0 2.90E+06 1.30E+06 - - - 2.0682 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17423.17423.2 0.162 14-Oct K.IDLTLLNR.L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 956.5655 1.22 4463 17423 2 956.567671 479.29 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.84 3438 - 3.87E+06 - - - 2.2894 - 2.182 0.291 - 332 1 2 0 0.0022 8 0 0 0 1.33E+08 1.09E+08 - - - 3.5428 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17425.17425.2 0.0248 14-Sep R.LLNIWQER[166.11].S sp|Q9NQG5|RPR1B_HUMAN 1 1080.5955 3.23 4465 17425 2 1080.596643 541.3051 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 6 3438.1 - 3.99E+06 - - - 1.0124 - 1.972 0.284 - 277.2 1 2 0 0.0011 8 0 0 0 1.06E+08 3.29E+07 - - - 3.1863 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.17426.17426.3 8.08E-05 13/48 K.LLLGAGAVAYGVR.E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1258.7398 1.49 4466 17426 3 1258.741504 420.5872 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3438.1 - 2.42E+06 - - - 1.3879 - 2.23 0.374 - 214.9 1 2 0 0.0017 13 0 0 0 1.88E+07 1.27E+07 - - - 4.8837 1 230117_WJC_METTL3_WT_vs_EV_F01.17427.17427.2 0.0001 18-Nov K.WVGVILDEAK.G "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1128.6179 3.14 4467 17427 2 1128.619818 565.3162 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3438.2 - 1.80E+06 - - - 1.6906 - 2.238 0.52 - 417.6 1 2 0 0.0019 10 0 0 0 2.09E+08 6.66E+07 - - - 5.1297 1 230117_WJC_METTL3_WT_vs_EV_F01.17428.17428.2 1.47E-06 18-Dec K.VVDDEIYYFR.K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1317.6241 2.04 4468 17428 2 1317.624554 659.8193 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3438.3 - 1.96E+06 - - - 0.3309 - 2.114 0.543 - 554.3 1 2 0 0.0004 10 0 0 0 2.70E+07 1.32E+07 - - - 5.141 1 230117_WJC_METTL3_WT_vs_EV_F01.17431.17431.2 0.000156 28-Dec R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 4.51 4471 17431 2 1494.918932 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3438.6 - 500603 - - - 1.8576 - 2.165 0.505 - 384.6 1 2 0 0.0028 15 0 0 0 6.48E+07 1.43E+07 - - - 4.6691 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.17433.17433.2 0.139 12-Aug K.TYDLLFK.L sp|P61026|RAB10_HUMAN 1 898.48 1.02 4472 17433 2 898.479793 450.2473 Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1 5.5 3438.9 - 764536 - - - -0.2526 - 1.473 0.247 - 204.2 1 2 0 -0.0002 7 0 0 0 2.19E+07 2.15E+07 - - - 2.0925 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.17438.17438.2 0.000215 13/22 R.YVVGVLEAAGVR[166.11].Y sp|Q9H9S5|FKRP_HUMAN 1 1241.7007 0.36 4476 17438 2 1241.70284 621.8576 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 6 3439.4 - 1.16E+06 - - - 1.6896 - 2.28 0.139 - 525 1 2 0 0.0021 12 0 0 0 9.52E+06 2.62E+07 - - - 2.2355 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.17439.17439.2 3.64E-05 18-Nov K.WVGVILDEAK[136.11].G "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1136.6321 3 4477 17439 2 1136.632 569.3233 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3439.5 - 1.06E+06 - - - -0.0968 - 2.094 0.46 - 336.7 1 2 0 -0.0001 10 0 0 0 2.00E+08 6.66E+07 - - - 4.5015 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17440.17440.2 4.30E-05 18-Nov K.VVDDEIYYFR[166.11].K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1327.6324 2.03 4478 17440 2 1327.634778 664.8235 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3439.6 - 1.92E+06 - - - 1.8002 - 1.818 0.437 - 475.6 1 2 0 0.0024 10 0 0 0 2.70E+07 1.33E+07 - - - 3.9364 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17441.17441.2 0.0077 16-Aug R.TFTNVYWMK[136.11].V sp|Q9HBH1|DEFM_HUMAN 1 1196.578 0.96 4479 17441 2 1196.581007 599.2963 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 8.26 3439.7 - 584876 - - - 2.5414 - 1.548 0.41 - 202 1 2 0 0.003 9 0 0 0 5.65E+06 5.91E+06 - - - 3.3325 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17445.17445.2 0.0171 16-Nov R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 0.92 4481 17445 2 997.606948 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3440.3 - 2.14E+07 - - - 1.7853 - 2.322 0.399 - 328.9 1 2 0 0.0018 9 0 0 0 4.11E+09 4.45E+09 - - - 4.4246 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.17448.17448.2 0.249 18-Sep K.VALAVSLNLR[166.11].T "sp|Q03426|KIME_HUMAN,tr|F5GXC0|F5GXC0_HUMAN,tr|F5H163|F5H163_HUMAN,tr|F5H092|F5H092_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|F5H368|F5H368_HUMAN,tr|A0A1W2PS16|A0A1W2PS16_HUMAN" 7 1064.6581 1.08 4484 17448 2 1064.661215 533.3364 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 9.72 3440.5 - 1.59E+06 - - - 2.8798 - 1.817 0.287 - 218.2 1 2 0 0.0031 10 0 0 0 1.18E+07 1.09E+07 - - - 2.8267 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17452.17452.2 0.000598 18-Oct R.VVLPIEAPIR[166.11].M sp|P00403|COX2_HUMAN 1 1115.6942 1.56 4488 17452 2 1115.695715 558.8544 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 5.97 3440.9 - 933591 - - - 1.3579 - 1.983 0.428 - 400.6 1 2 0 0.0015 10 0 0 0 6.36E+08 4.08E+08 - - - 4.1127 0.9836 230117_WJC_METTL3_WT_vs_EV_F01.17460.17460.2 0.282 16-Apr R.MLPPPPMWR[166.11].R "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 5 1133.5753 0.75 4495 17460 2 1133.578268 567.795 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 9.5 3441.8 - 605128 - - - 2.5759 - 1.107 0.214 - 37.2 16 2 0 0.0029 9 0 0 0 1.80E+07 2.40E+07 - - - 0.3769 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17466.17466.2 0.0112 16-Sep R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.92 4499 17466 2 989.592703 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3442.6 - 7.17E+07 - - - 1.7543 - 2.071 0.398 - 237.8 1 2 0 0.0017 9 0 0 0 4.12E+09 4.46E+09 - - - 4.0863 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17467.17467.2 0.0269 16-Oct K.VVLPC[160.03]NLLR[166.11].M "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1092.6353 9.7 4500 17467 2 1092.636315 547.3249 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 8.22 3442.6 - 2.78E+06 - - - 0.9235 - 1.523 0.41 - 426.4 1 2 0 0.001 9 0 0 0 7.56E+08 7.80E+07 - - - 3.286 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17468.17468.2 0.000706 18-Aug R.VVLPIEAPIR.M sp|P00403|COX2_HUMAN 1 1105.6859 1.56 4501 17468 2 1105.6883 553.8502 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 5.97 3442.7 - 3.02E+06 - - - 2.1435 - 1.631 0.416 - 244.2 1 2 0 0.0024 10 0 0 0 6.36E+08 4.08E+08 - - - 3.4783 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.17469.17469.2 0.0248 18-Dec K.VALAVSLNLR.T "sp|Q03426|KIME_HUMAN,tr|F5GXC0|F5GXC0_HUMAN,tr|F5H163|F5H163_HUMAN,tr|F5H092|F5H092_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|F5H368|F5H368_HUMAN,tr|A0A1W2PS16|A0A1W2PS16_HUMAN" 7 1054.6499 1.08 4502 17469 2 1054.652349 528.3322 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 9.72 3442.8 - 937842 - - - 2.342 - 2.368 0.317 - 424.7 1 2 0 0.0025 10 0 0 0 1.18E+07 1.09E+07 - - - 3.7878 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.17474.17474.2 0.00266 26-Sep K.LGGSAVISLEGKPL.- "sp|P23528|COF1_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PK25|E9PK25_HUMAN" 3 1339.7711 11.36 4507 17474 2 1339.771903 670.8928 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6 3443.5 - 153989 - - - 0.5867 - 1.673 0.307 - 101.4 1 2 0 0.0008 14 0 0 0 2.09E+06 1.84E+05 - - - 2.5997 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.17483.17483.2 0.0798 18-Oct K.IYVISLAEPR.L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1159.6601 1.26 4514 17483 2 1159.665518 580.8373 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3444.6 - 363686 - - - 4.6634 - 1.866 0.372 - 329.1 1 2 0 0.0054 10 0 0 0 1.92E+08 1.52E+08 - - - 3.5281 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.17487.17487.2 0.0179 18-Aug K.IYVISLAEPR[166.11].L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1169.6684 1.26 4516 17487 2 1169.669108 585.8415 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3445.1 - 275063 - - - 0.6224 - 1.734 0.212 - 166.4 1 2 0 0.0007 10 0 0 0 1.91E+08 1.52E+08 - - - 2.143 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.17488.17488.2 0.0226 14-Aug K.FYFEELGK[136.11].Y sp|Q10471|GALT2_HUMAN 1 1039.5106 0.79 4517 17488 2 1039.509333 520.7626 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3445.2 - 475899 - - - -1.2169 - 1.305 0.36 - 131.1 1 2 0 -0.0013 8 0 0 0 5.72E+07 7.25E+07 - - - 2.5024 0.992 230117_WJC_METTL3_WT_vs_EV_F01.17494.17494.2 0.408 16-May R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 8937.03 4522 17494 2 1006.569943 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3445.9 - 6.86E+08 - - - 0.0447 - 1.024 0.242 - 53 1 2 0 0 9 0 0 0 2.55E+11 2.85E+07 - - - 0.897 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.17496.17496.2 0.00649 14-Sep K.DIVYIGLR.D "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN" 2 947.544 75.47 4523 17496 2 947.543235 474.7793 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 5.84 3446.1 - 1.50E+06 - - - -0.8253 - 1.755 0.333 - 332.6 1 2 0 -0.0008 8 0 0 0 2.73E+07 3.62E+05 - - - 3.1967 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.17500.17500.2 0.364 18-Oct R.FSNLLGTVYR[166.11].R "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN,tr|C9J544|C9J544_HUMAN" 3 1178.6323 0.65 4527 17500 2 1178.632486 590.3234 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 8.75 3446.6 - 608330 - - - 0.1341 - 1.703 0.176 - 307.8 1 2 0 0.0002 10 0 0 0 8.68E+06 1.34E+07 - - - 1.827 0.978 230117_WJC_METTL3_WT_vs_EV_F01.17507.17507.2 0.00233 20-Oct R.FLPEFAGTQLK.L sp|Q9UBZ4|APEX2_HUMAN 1 1249.6707 1.6 4532 17507 2 1249.664673 625.8426 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 6 3447.5 - 2.51E+06 - - - -4.8021 - 1.653 0.311 - 325.4 1 2 0 -0.006 11 0 0 0 1.17E+08 7.30E+07 - - - 2.6958 0.885 230117_WJC_METTL3_WT_vs_EV_F01.17516.17516.2 0.00603 14-Jul K.FDTPFLPK.P sp|Q14684|RRP1B_HUMAN 1 963.5066 1.3 4538 17516 2 963.509074 482.7606 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.84 3448.5 - 926495 - - - 2.5999 - 1.35 0.314 - 104.7 1 1 0 0.0025 8 0 0 0 1.56E+08 1.21E+08 - - - 2.2645 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17522.17522.2 0.000193 18-Oct R.AAGVVLEMIR[166.11].E "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN,tr|M0QXI6|M0QXI6_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 4 1067.6037 1.59 4543 17522 2 1067.604949 534.8091 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6.05 3449.2 - 734826 - - - 1.1971 - 2.116 0.423 - 363.3 1 2 0 0.0013 10 0 0 0 6.02E+07 3.80E+07 - - - 4.257 1 230117_WJC_METTL3_WT_vs_EV_F01.17525.17525.2 2.12E-07 13/18 N.PEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1087.5662 442.39 4544 17525 2 1087.564349 544.7904 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.43 3449.6 - 3.79E+06 - - - -1.7102 - 2.536 0.443 - 746 1 1 0 -0.0019 10 0 0 0 1.38E+08 3.11E+05 - - - 4.91 0.9951 230117_WJC_METTL3_WT_vs_EV_F01.17529.17529.2 0.0105 12-Jun K.FIDPFC[160.03]R.L sp|P56182|RRP1_HUMAN 1 953.4429 1.11 4548 17529 2 953.441139 477.7287 Ribosomal RNA processing protein 1 homolog A OS=Homo sapiens OX=9606 GN=RRP1 PE=1 SV=1 5.83 3450 - 2.06E+06 - - - -1.8711 - 1.169 0.38 - 99.9 1 2 0 -0.0018 7 0 0 0 1.96E+07 1.77E+07 - - - 2.3419 0.8942 230117_WJC_METTL3_WT_vs_EV_F01.17534.17534.2 0.00743 14-Sep K.FDTPFLPK[136.11].P sp|Q14684|RRP1B_HUMAN 1 971.5208 1.43 4552 17534 2 971.519044 486.7677 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.84 3450.6 - 703241 - - - -1.7756 - 1.717 0.436 - 226 1 1 0 -0.0017 8 0 0 0 1.75E+08 1.22E+08 - - - 3.8911 0.9462 230117_WJC_METTL3_WT_vs_EV_F01.17538.17538.2 0.000177 18-Nov R.LLFNDVQTLK[136.11].D "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1197.6849 1.36 4553 17538 2 1197.674838 599.8497 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.84 3451.2 - 1.59E+06 - - - -8.3795 - 2.215 0.401 - 327.1 1 2 0 -0.01 10 0 0 0 3.93E+07 2.89E+07 - - - 4.2194 1 230117_WJC_METTL3_WT_vs_EV_F01.17541.17541.2 0.000399 16-Nov R.PLVALLDGR.D "sp|P56545|CTBP2_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|E7ESU7|E7ESU7_HUMAN,tr|E7EUB3|E7EUB3_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|E7EPF8|E7EPF8_HUMAN,tr|E9PGB1|E9PGB1_HUMAN" 7 952.5706 1.62 4555 17541 2 952.564777 477.2926 C-terminal-binding protein 2 OS=Homo sapiens OX=9606 GN=CTBP2 PE=1 SV=1 6.27 3451.6 - 2.51E+06 - - - -6.0772 - 2.347 0.437 - 505.6 1 1 0 -0.0058 9 0 0 0 1.07E+08 6.58E+07 - - - 4.735 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.17559.17559.2 0.238 14-Sep R.GIFEPFGK.L "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 893.4647 0.78 4563 17559 2 893.463665 447.7396 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 6 3453.7 - 1.13E+06 - - - -1.1629 - 1.51 0.271 - 278 1 2 0 -0.001 8 0 0 0 1.39E+08 1.78E+08 - - - 2.2852 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17563.17563.2 0.0207 16-Nov K.IAFAITAIK.G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 946.5852 1.2 4564 17563 2 946.586774 474.2999 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3454.3 - 3.71E+06 - - - 1.7114 - 2.336 0.349 - 326.8 1 2 0 0.0016 9 0 0 0 5.18E+09 4.33E+09 - - - 4.0728 0.927 230117_WJC_METTL3_WT_vs_EV_F01.17564.17564.2 0.395 12-May K.LVLPMIK.E "sp|O00410|IPO5_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 2 812.5194 2.68 4565 17564 2 812.516805 407.267 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 8.75 3454.4 - 0 - - - -3.1716 - 1.291 0.115 - 82.1 1 2 0 -0.0026 7 0 0 0 3.87E+07 1.44E+07 - - - 0.6989 1 230117_WJC_METTL3_WT_vs_EV_F01.17574.17574.2 6.65E-07 20-Dec R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 999 4571 17574 2 1201.606445 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3455.6 - 956798 - - - -2.2403 - 2.645 0.549 - 688.3 1 2 0 -0.0027 11 0 0 0 2.23E+07 0.00E+00 - - - 5.7264 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17575.17575.2 0.012 16-Dec K.IAFAITAIK[136.11].G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 954.5994 1.2 4572 17575 2 954.601795 478.307 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3455.8 - 2.60E+06 - - - 2.5571 - 2.4 0.325 - 338.6 1 2 0 0.0024 9 0 0 0 5.18E+09 4.33E+09 - - - 3.9735 0.8697 230117_WJC_METTL3_WT_vs_EV_F01.17583.17583.2 0.0166 16-Aug K.LAFNSLLEK[136.11].A "sp|O75400|PR40A_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 2 1041.595 1.46 4575 17583 2 1041.587549 521.8048 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 6 3456.8 - 2.41E+06 - - - -7.1506 - 1.492 0.268 - 142 1 2 0 -0.0074 9 0 0 0 1.34E+08 9.19E+07 - - - 2.1757 0.9805 230117_WJC_METTL3_WT_vs_EV_F01.17585.17585.2 0.0544 14-Jul R.FLDDLGLK.F sp|Q14126|DSG2_HUMAN 1 919.5015 1.36 4577 17585 2 919.496772 460.758 Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2 4.21 3457.1 - 2.59E+06 - - - -5.1245 - 1.674 0.34 - 111.9 1 2 0 -0.0047 8 0 0 0 4.77E+07 3.51E+07 - - - 3.1046 0.9929 230117_WJC_METTL3_WT_vs_EV_F01.17586.17586.2 0.00217 20-Aug R.FLPEFAGTQLK[136.11].L sp|Q9UBZ4|APEX2_HUMAN 1 1257.6849 1.6 4578 17586 2 1257.681614 629.8497 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 6 3457.2 - 2.37E+06 - - - -2.5921 - 1.494 0.312 - 183 1 2 0 -0.0033 11 0 0 0 1.17E+08 7.30E+07 - - - 2.4304 0.9251 230117_WJC_METTL3_WT_vs_EV_F01.17602.17602.2 0.0379 16-Sep K.SALLALGLK.C sp|Q12874|SF3A3_HUMAN 1 884.5695 3.49 4582 17602 2 884.563679 443.292 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3459.4 - 1.54E+06 - - - -6.5851 - 1.86 0.224 - 242.8 1 2 0 -0.0058 9 0 0 0 2.69E+08 7.70E+07 - - - 2.489 0.9607 230117_WJC_METTL3_WT_vs_EV_F01.17603.17603.2 1.83 14-Aug K.GLGILSLK[136.11].Q sp|Q92616|GCN1_HUMAN 1 807.5309 0.86 4583 17603 2 807.527987 404.7727 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.75 3459.5 - 1.53E+06 - - - -3.6568 - 1.474 0.165 - 188.2 1 2 0 -0.003 8 0 0 0 3.84E+07 4.49E+07 - - - 1.4289 0.997 230117_WJC_METTL3_WT_vs_EV_F01.17606.17606.2 0.789 14-Aug R.AYILNLVK.Q sp|P50991|TCPD_HUMAN 1 932.5695 7.6 4585 17606 2 932.569404 467.292 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.63 3459.9 - 9.01E+06 - - - -0.1072 - 1.387 0.233 - 221.3 1 2 0 -0.0001 8 0 0 0 2.82E+08 3.71E+07 - - - 1.7486 1 230117_WJC_METTL3_WT_vs_EV_F01.17608.17608.2 7.66E-07 13/20 R.MGPGIGAILER.S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1112.6012 2.12 4586 17608 2 1112.595685 557.3079 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.75 3460.1 - 5.87E+06 - - - -4.9694 - 2.358 0.558 - 583.8 1 2 0 -0.0055 11 0 0 0 2.38E+08 1.12E+08 - - - 5.4812 1 230117_WJC_METTL3_WT_vs_EV_F01.17609.17609.2 2.25E-07 13/20 R.MGPGIGAILER[166.11].S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1122.6095 2.12 4587 17609 2 1122.606632 562.312 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.75 3460.1 - 2.65E+06 - - - -2.5405 - 2.06 0.565 - 573.7 1 2 0 -0.0029 11 0 0 0 2.38E+08 1.12E+08 - - - 5.1683 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17616.17616.2 0.00741 18-Sep R.LGLPGEVFGR[166.11].S sp|O95409|ZIC2_HUMAN 1 1053.5847 2.6 4591 17616 2 1053.587321 527.7996 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 6 3460.8 - 3.20E+06 - - - 2.5352 - 1.789 0.432 - 179.2 1 2 0 0.0027 10 0 0 0 3.09E+08 1.19E+08 - - - 3.8545 0.9962 230117_WJC_METTL3_WT_vs_EV_F01.17618.17618.2 0.0495 18-Aug R.LGLPGEVFGR.S sp|O95409|ZIC2_HUMAN 1 1043.5764 2.61 4593 17618 2 1043.574739 522.7955 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 6 3461 - 6.94E+06 - - - -1.5725 - 1.625 0.273 - 130.9 1 2 0 -0.0016 10 0 0 0 3.10E+08 1.19E+08 - - - 2.4121 0.9858 230117_WJC_METTL3_WT_vs_EV_F01.17619.17619.2 0.00759 20-Dec R.ALTALGLAVPR.G sp|Q9BVQ7|SPA5L_HUMAN 1 1080.6655 5.78 4594 17619 2 1080.660003 541.34 Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2 9.79 3461.1 - 4.38E+06 - - - -5.1135 - 2.458 0.284 - 585.8 1 2 0 -0.0055 11 0 0 0 4.53E+07 7.84E+06 - - - 3.5698 0.999 230117_WJC_METTL3_WT_vs_EV_F01.17621.17621.2 0.0209 18-Oct R.LAGLSAALLR.T "sp|P51649|SSDH_HUMAN,tr|A0A5F9ZH98|A0A5F9ZH98_HUMAN,tr|C9J8Q5|C9J8Q5_HUMAN" 3 983.6128 0.88 4596 17621 2 983.615837 492.8137 "Succinate-semialdehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH5A1 PE=1 SV=2" 9.75 3461.4 - 1.52E+06 - - - 3.1232 - 1.941 0.315 - 243.3 1 2 0 0.0031 10 0 0 0 2.56E+07 2.90E+07 - - - 3.2178 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.17644.17644.2 0.0215 16-Sep K.SALLALGLK[136.11].C sp|Q12874|SF3A3_HUMAN 1 892.5837 3.51 4607 17644 2 892.584279 447.2991 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3464.3 - 2.17E+06 - - - 0.6442 - 1.584 0.219 - 219.3 1 2 0 0.0006 9 0 0 0 2.69E+08 7.65E+07 - - - 1.989 0.9511 230117_WJC_METTL3_WT_vs_EV_F01.17648.17648.2 0.0828 16-Jul K.IFTQLEEFR[166.11].A sp|O60306|AQR_HUMAN 1 1191.6163 0.73 4609 17648 2 1191.608184 596.8154 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 4.53 3464.8 - 1.08E+06 - - - -6.8478 - 1.73 0.353 - 173.1 1 2 0 -0.0082 9 0 0 0 1.88E+07 2.57E+07 - - - 3.2314 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17650.17650.2 0.000601 16-Sep K.IFTQLEEFR.A sp|O60306|AQR_HUMAN 1 1181.6081 0.76 4611 17650 2 1181.610906 591.8113 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 4.53 3465 - 1.42E+06 - - - 2.3967 - 1.974 0.468 - 319.4 1 2 0 0.0028 9 0 0 0 1.87E+07 2.45E+07 - - - 4.4642 0.9951 230117_WJC_METTL3_WT_vs_EV_F01.17651.17651.2 0.00128 20-Oct R.ALTALGLAVPR[166.11].G sp|Q9BVQ7|SPA5L_HUMAN 1 1090.6738 5.78 4612 17651 2 1090.670174 546.3442 Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2 9.79 3465.1 - 1.05E+06 - - - -3.3236 - 2.02 0.345 - 229.3 1 2 0 -0.0036 11 0 0 0 4.53E+07 7.84E+06 - - - 3.4901 0.9946 230117_WJC_METTL3_WT_vs_EV_F01.17655.17655.2 2.27 14-Jul K.GLGILSLK.Q sp|Q92616|GCN1_HUMAN 1 799.5167 0.85 4614 17655 2 799.517821 400.7656 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.75 3465.6 - 1.23E+06 - - - 1.3521 - 1.338 0.153 - 153.4 2 2 0 0.0011 8 0 0 0 3.80E+07 4.45E+07 - - - 0.9144 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.17657.17657.2 0.00016 20-Oct K.LGNPIVPLNIR.L sp|P78527|PRKDC_HUMAN 1 1204.7292 0.93 4616 17657 2 1204.727856 603.3719 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3465.9 - 884202 - - - -1.109 - 1.947 0.428 - 328.3 1 2 0 -0.0013 11 0 0 0 1.69E+07 1.82E+07 - - - 4.0043 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.17658.17658.2 0.0028 18-Oct K.LTYGTMVFVR[166.11].S sp|Q15067|ACOX1_HUMAN 1 1195.6299 1.09 4617 17658 2 1195.628361 598.8222 Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3 8.75 3466 - 746746 - - - -1.2755 - 1.756 0.409 - 296.8 1 2 0 -0.0015 10 0 0 0 1.24E+07 1.14E+07 - - - 3.633 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.17663.17663.2 0.0146 14-Aug K.IIDFGLAR.R "sp|Q86YV6|MYLK4_HUMAN,sp|Q32MK0|MYLK3_HUMAN,sp|Q9H1R3|MYLK2_HUMAN,sp|P53778|MK12_HUMAN,sp|O15264|MK13_HUMAN,sp|P45983|MK08_HUMAN,sp|Q16539|MK14_HUMAN,sp|P45984|MK09_HUMAN,sp|Q15759|MK11_HUMAN,sp|P53779|MK10_HUMAN,sp|Q15746|MYLK_HUMAN,tr|A0A286YFD7|A0A286YFD7_HUMAN,tr|A0A286YES0|A0A286YES0_HUMAN,tr|A0A286YEQ0|A0A286YEQ0_HUMAN,tr|A0A286YEX7|A0A286YEX7_HUMAN,tr|A0A286YFC0|A0A286YFC0_HUMAN,tr|B5MDL5|B5MDL5_HUMAN,tr|A0A286YES9|A0A286YES9_HUMAN,tr|A0A286YF97|A0A286YF97_HUMAN,tr|D6RCB1|D6RCB1_HUMAN,tr|A0A286YF19|A0A286YF19_HUMAN,tr|A0A286YFN2|A0A286YFN2_HUMAN,tr|D6RJF9|D6RJF9_HUMAN,tr|A0A286YEY0|A0A286YEY0_HUMAN,tr|Q5R3E6|Q5R3E6_HUMAN,tr|A0A286YEV8|A0A286YEV8_HUMAN,tr|B4E0K5|B4E0K5_HUMAN,tr|A0A286YF85|A0A286YF85_HUMAN,tr|A0A286YFI3|A0A286YFI3_HUMAN,tr|F8W9R5|F8W9R5_HUMAN,tr|A0A2R8Y4U5|A0A2R8Y4U5_HUMAN,tr|A0A286YFM6|A0A286YFM6_HUMAN,tr|A0A286YEV3|A0A286YEV3_HUMAN,tr|A0A286YF83|A0A286YF83_HUMAN,tr|A0A286YFJ6|A0A286YFJ6_HUMAN,tr|A0A286YF62|A0A286YF62_HUMAN,tr|A0A286YF02|A0A286YF02_HUMAN,tr|J3KNK1|J3KNK1_HUMAN,tr|A0A286YEQ7|A0A286YEQ7_HUMAN,tr|A0A286YFJ4|A0A286YFJ4_HUMAN,tr|A0A1W2PPZ3|A0A1W2PPZ3_HUMAN,tr|A0A286YEN5|A0A286YEN5_HUMAN,tr|A0A286YFA6|A0A286YFA6_HUMAN,tr|A0A1P0B7D2|A0A1P0B7D2_HUMAN,tr|A0A1W2PRF2|A0A1W2PRF2_HUMAN,tr|D7R525|D7R525_HUMAN,tr|A0A286YF35|A0A286YF35_HUMAN,tr|A0A286YFB6|A0A286YFB6_HUMAN,tr|A0A286YFE2|A0A286YFE2_HUMAN,tr|A0A286YEW9|A0A286YEW9_HUMAN,tr|E7EX54|E7EX54_HUMAN" 51 903.5178 2.64 4620 17663 2 903.51872 452.7662 Myosin light chain kinase family member 4 OS=Homo sapiens OX=9606 GN=MYLK4 PE=1 SV=2 5.84 3466.6 - 1.06E+06 - - - 1.016 - 1.835 0.134 - 166.6 1 2 0 0.0009 8 0 0 0 3.60E+07 1.36E+07 - - - 1.8613 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17664.17664.2 0.00254 20-Aug K.LGNPIVPLNIR[166.11].L sp|P78527|PRKDC_HUMAN 1 1214.7375 0.93 4621 17664 2 1214.737536 608.376 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3466.7 - 1.05E+06 - - - 0.0609 - 1.723 0.359 - 169.3 1 2 0 0.0001 11 0 0 0 1.69E+07 1.82E+07 - - - 3.1644 1 230117_WJC_METTL3_WT_vs_EV_F01.17675.17675.2 1.82E-05 13/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 6.58 4630 17675 2 1484.912071 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3468.1 - 545932 - - - 2.819 - 2.321 0.52 - 379.2 1 2 0 0.0042 15 0 0 0 8.28E+07 1.26E+07 - - - 4.9505 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.17677.17677.2 0.0703 16-Jul K.ALQFLEEVK.V sp|P40227|TCPZ_HUMAN 1 1075.5914 11 4631 17677 2 1075.590648 538.803 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 3468.3 - 3.04E+06 - - - -0.6629 - 1.678 0.238 - 140.8 1 2 0 -0.0007 9 0 0 0 5.75E+07 5.23E+06 - - - 2.2961 0.9935 230117_WJC_METTL3_WT_vs_EV_F01.17678.17678.2 0.00869 14-Jun R.GLFIIDGK.G sp|P32119|PRDX2_HUMAN 1 861.496 2.47 4632 17678 2 861.494531 431.7553 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3468.4 - 1.41E+06 - - - -1.7098 - 1.354 0.272 - 143.9 1 2 0 -0.0015 8 0 0 0 5.62E+08 2.27E+08 - - - 1.9636 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.17682.17682.2 0.000873 20-Sep K.FSPAGPILSIR.L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1156.6604 1.03 4634 17682 2 1156.659515 579.3375 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3468.9 - 1.68E+06 - - - -0.8032 - 1.902 0.265 - 309.1 1 2 0 -0.0009 11 0 0 0 9.42E+08 9.16E+08 - - - 2.7372 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.17684.17684.2 0.00107 14-Aug R.GLFIIDGK[136.11].G sp|P32119|PRDX2_HUMAN 1 869.5102 2.47 4636 17684 2 869.509049 435.7624 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3469.1 - 1.55E+06 - - - -1.3283 - 1.516 0.383 - 282.9 1 2 0 -0.0012 8 0 0 0 5.62E+08 2.27E+08 - - - 3.1243 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.17696.17696.2 0.0132 12-Jun K.SYFLIVR.K sp|O00429|DNM1L_HUMAN 1 896.512 7.7 4646 17696 2 896.511856 449.2633 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 8.46 3470.6 - 300814 - - - -0.1484 - 1.26 0.406 - 99.6 1 2 0 -0.0001 7 0 0 0 2.43E+07 3.16E+06 - - - 2.772 1 230117_WJC_METTL3_WT_vs_EV_F01.17700.17700.2 4.34E-07 18-Dec K.VGDQILLAIK.G sp|Q6P1L8|RM14_HUMAN 1 1068.6543 1.75 4648 17700 2 1068.652929 535.3344 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3471.1 - 1.75E+06 - - - -1.2792 - 2.741 0.52 - 503.6 1 2 0 -0.0014 10 0 0 0 1.09E+08 6.25E+07 - - - 5.6958 0.9768 230117_WJC_METTL3_WT_vs_EV_F01.17701.17701.2 0.00275 18-Nov D.TLDNDIMLIK.L "sp|P35030|TRY3_HUMAN,tr|A0A7P0MNE9|A0A7P0MNE9_HUMAN" 2 1174.6268 68.28 4649 17701 2 1174.629102 588.3207 Trypsin-3 OS=Homo sapiens OX=9606 GN=PRSS3 PE=1 SV=2 4.21 3471.3 - 1.51E+06 - - - 1.993 - 1.909 0.48 - 253.9 1 1 0 0.0023 10 0 0 0 1.24E+08 1.81E+06 - - - 4.3903 0.9467 230117_WJC_METTL3_WT_vs_EV_F01.17703.17703.2 3.8 12-Apr K.FIPEFIR[166.11].K "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|A0A804HIK9|A0A804HIK9_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 5 930.5203 13.37 4651 17703 2 930.520283 466.2674 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6 3471.5 - 470097 - - - 0.0258 - 1.06 0.101 - 44.3 7 2 0 0 7 0 0 0 8.83E+08 6.61E+07 - - - -0.4059 1 230117_WJC_METTL3_WT_vs_EV_F01.17705.17705.2 4.19E-06 13/20 K.VLADLAIYEPK[136.11].T sp|Q9BYC9|RM20_HUMAN 1 1238.7002 0.83 4653 17705 2 1238.701696 620.3574 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3471.8 - 268831 - - - 1.2158 - 2.384 0.438 - 475.9 1 2 0 0.0015 11 0 0 0 1.96E+07 2.36E+07 - - - 4.6258 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17709.17709.2 0.01 16-Oct R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 0.89 4656 17709 2 997.605622 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3472.1 - 1.94E+06 - - - 0.4561 - 2.236 0.435 - 271.7 1 2 0 0.0005 9 0 0 0 2.35E+08 2.62E+08 - - - 4.5818 1 230117_WJC_METTL3_WT_vs_EV_F01.17713.17713.2 1.46E-05 18-Nov K.LGDDIDLIVR[166.11].C sp|O15371|EIF3D_HUMAN 1 1137.6269 1.08 4658 17713 2 1137.622978 569.8207 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3472.5 - 360728 - - - -3.4554 - 2.414 0.477 - 308 1 2 0 -0.0039 10 0 0 0 3.25E+08 3.01E+08 - - - 5.0228 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17717.17717.2 0.0288 16-Sep R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.89 4661 17717 2 989.59211 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3472.9 - 4.34E+06 - - - 1.155 - 2.047 0.229 - 208.8 1 2 0 0.0011 9 0 0 0 2.23E+08 2.51E+08 - - - 2.8045 1 230117_WJC_METTL3_WT_vs_EV_F01.17720.17720.2 3.18E-05 18-Dec K.LGDDIDLIVR.C sp|O15371|EIF3D_HUMAN 1 1127.6186 1.08 4663 17720 2 1127.610785 564.8166 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3473.3 - 981066 - - - -6.9651 - 2.369 0.475 - 351.7 1 2 0 -0.0079 10 0 0 0 3.25E+08 3.01E+08 - - - 4.9543 0.991 230117_WJC_METTL3_WT_vs_EV_F01.17721.17721.2 0.00123 14-Aug R.GLFIIDDK[136.11].G "sp|Q06830|PRDX1_HUMAN,sp|Q13162|PRDX4_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|H7C3T4|H7C3T4_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 5 927.5157 2.1 4664 17721 2 927.515822 464.7651 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.21 3473.4 - 458285 - - - 0.1488 - 1.761 0.003 - 232 1 2 0 0.0001 8 0 0 0 1.82E+09 8.66E+08 - - - 0.7698 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.17723.17723.2 0.0387 20-Oct K.ANLIVLGAVPR[166.11].L "sp|Q8IUR7|ARMC8_HUMAN,tr|G5E9V6|G5E9V6_HUMAN,tr|C9J8P8|C9J8P8_HUMAN,tr|C9JBY2|C9JBY2_HUMAN,tr|G5E9V7|G5E9V7_HUMAN,tr|C9JAA7|C9JAA7_HUMAN,tr|B7Z637|B7Z637_HUMAN" 7 1131.7003 2.56 4666 17723 2 1131.700164 566.8575 Armadillo repeat-containing protein 8 OS=Homo sapiens OX=9606 GN=ARMC8 PE=1 SV=2 9.79 3473.6 - 273315 - - - -0.1626 - 2.143 0.29 - 252.5 1 2 0 -0.0002 11 0 0 0 2.16E+07 8.44E+06 - - - 3.2448 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.17728.17728.2 0.000358 18-Nov K.VGDQILLAIK[136.11].G sp|Q6P1L8|RM14_HUMAN 1 1076.6685 1.75 4669 17728 2 1076.667343 539.3415 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3474.3 - 3.19E+06 - - - -1.0709 - 2.095 0.427 - 320.9 1 2 0 -0.0012 10 0 0 0 1.09E+08 6.25E+07 - - - 4.2588 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.17729.17729.2 0.0192 14-Sep K.TTQLLFLK.A sp|O94874|UFL1_HUMAN 1 962.5801 1.91 4670 17729 2 962.58087 482.2973 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 8.41 3474.4 - 1.13E+06 - - - 0.8332 - 1.563 0.289 - 200.2 1 2 0 0.0008 8 0 0 0 2.47E+07 1.29E+07 - - - 2.5222 0.9308 230117_WJC_METTL3_WT_vs_EV_F01.17731.17731.2 2.82 12-Apr K.DFLLSLK.T sp|Q86UP2|KTN1_HUMAN 1 834.4851 0.47 4672 17731 2 834.48672 418.2498 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.84 3474.6 - 681550 - - - 1.9353 - 0.972 0.105 - 51.3 12 2 0 0.0016 7 0 0 0 1.15E+07 2.43E+07 - - - -0.756 1 230117_WJC_METTL3_WT_vs_EV_F01.17734.17734.2 0.000119 18-Oct R.FQSLGVAFYR.G "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1186.6135 1.56 4674 17734 2 1186.612708 594.314 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 8.75 3475 - 2.36E+06 - - - -0.6624 - 2.089 0.474 - 327.8 1 2 0 -0.0008 10 0 0 0 5.51E+07 3.53E+07 - - - 4.598 0.9605 230117_WJC_METTL3_WT_vs_EV_F01.17736.17736.2 0.836 12-May R.IIFDDFR[166.11].E sp|P46977|STT3A_HUMAN 1 934.4788 1.07 4675 17736 2 934.479294 468.2467 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.21 3475.2 - 564156 - - - 0.5415 - 0.937 0.11 - 64 1 2 0 0.0005 7 0 0 0 1.55E+08 1.45E+08 - - - -0.3529 0.9242 230117_WJC_METTL3_WT_vs_EV_F01.17737.17737.2 0.288 16-Jul R.AVPPFVFTR.R "sp|O75896|TUSC2_HUMAN,tr|G3V0I0|G3V0I0_HUMAN,tr|F2Z2A9|F2Z2A9_HUMAN" 3 1032.5757 2.13 4676 17737 2 1032.581065 517.2951 Tumor suppressor candidate 2 OS=Homo sapiens OX=9606 GN=TUSC2 PE=1 SV=3 9.79 3475.2 - 996399 - - - 5.2422 - 1.284 0.116 - 115.8 2 2 0 0.0054 9 0 0 0 1.79E+07 8.41E+06 - - - 0.4848 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17738.17738.2 0.000328 20-Sep K.VYGAILVAVER.L sp|Q9Y6J9|TAF6L_HUMAN 1 1188.6867 1.13 4677 17738 2 1188.687913 595.3506 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 5.97 3475.3 - 1.57E+06 - - - 1.0549 - 2 0.452 - 225.4 1 2 0 0.0013 11 0 0 0 3.48E+07 3.07E+07 - - - 4.2542 0.9896 230117_WJC_METTL3_WT_vs_EV_F01.17743.17743.2 0.0913 16-Aug K.FLLENSVLK.M "sp|Q92696|PGTA_HUMAN,tr|H0YMG5|H0YMG5_HUMAN,tr|H0YKZ8|H0YKZ8_HUMAN,tr|H0YLG7|H0YLG7_HUMAN" 4 1061.6121 10.09 4680 17743 2 1061.610846 531.8133 Geranylgeranyl transferase type-2 subunit alpha OS=Homo sapiens OX=9606 GN=RABGGTA PE=1 SV=2 6 3475.9 - 1.67E+06 - - - -1.1784 - 1.382 0.174 - 154.1 1 2 0 -0.0013 9 0 0 0 2.80E+07 2.77E+06 - - - 1.2618 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.17744.17744.2 0.0612 20-Dec K.VLADLAIYEPK.T sp|Q9BYC9|RM20_HUMAN 1 1230.686 0.83 4681 17744 2 1230.685829 616.3503 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3476.1 - 1.16E+06 - - - -0.1308 - 2.053 0.274 - 288.4 1 2 0 -0.0002 11 0 0 0 1.96E+07 2.36E+07 - - - 3.0106 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.17745.17745.2 0.15 18-Aug K.ALLAEGVILR.R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1053.6546 1.38 4682 17745 2 1053.655869 527.8346 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3476.1 - 1.52E+06 - - - 1.1759 - 1.905 0.166 - 164.3 1 2 0 0.0012 10 0 0 0 3.37E+08 2.45E+08 - - - 2.0656 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.17746.17746.2 1.69 12-Jul K.ITWSIIR[166.11].E sp|P38606|VATA_HUMAN 1 897.5312 1.17 4683 17746 2 897.532814 449.7729 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 9.75 3476.2 - 872733 - - - 1.8451 - 1.495 0.187 - 137.8 1 2 0 0.0017 7 0 0 0 1.57E+07 1.33E+07 - - - 1.6958 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17748.17748.2 0.00574 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 8937.03 4684 17748 2 1006.570931 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3476.5 - 2.23E+08 - - - 1.0263 - 1.939 0.476 - 258.8 1 2 0 0.001 9 0 0 0 2.55E+11 2.85E+07 - - - 4.4721 0.9937 230117_WJC_METTL3_WT_vs_EV_F01.17751.17751.2 0.163 12-Jul R.SIFDGFR.D sp|O94888|UBXN7_HUMAN 1 840.413 1.6 4686 17751 2 840.413537 421.2138 UBX domain-containing protein 7 OS=Homo sapiens OX=9606 GN=UBXN7 PE=1 SV=2 5.55 3476.8 - 439724 - - - 0.6354 - 1.228 0.162 - 160.7 1 2 0 0.0005 7 0 0 0 1.42E+07 8.90E+06 - - - 0.8881 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.17752.17752.2 1.01 13/18 K.ALLAEGVILR[166.11].R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1063.6629 1.38 4687 17752 2 1063.663291 532.8387 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3476.9 - 1.51E+06 - - - 0.3676 - 2.011 0.119 - 734 1 2 0 0.0004 10 0 0 0 3.37E+08 2.45E+08 - - - 1.8699 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.17754.17754.2 0.0291 18-Sep K.LLYPLQEVER[166.11].F "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 1268.7004 0.99 4689 17754 2 1268.702886 635.3575 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.53 3477.1 - 438268 - - - 1.9532 - 1.786 0.282 - 310.2 1 2 0 0.0025 10 0 0 0 1.07E+07 1.09E+07 - - - 2.742 0.9871 230117_WJC_METTL3_WT_vs_EV_F01.17755.17755.2 0.625 14-Aug K.TTQLLFLK[136.11].A sp|O94874|UFL1_HUMAN 1 970.5943 3.57 4690 17755 2 970.598852 486.3044 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 8.41 3477.2 - 408876 - - - 4.7229 - 1.393 0.213 - 153.7 1 2 0 0.0046 8 0 0 0 3.32E+07 9.30E+06 - - - 1.6124 0.9765 230117_WJC_METTL3_WT_vs_EV_F01.17764.17764.2 0.39 20-Aug R.ELLIIGGVAAR.D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1110.6761 1.15 4696 17764 2 1110.674526 556.3453 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3478.2 - 230259 - - - -1.4118 - 1.749 0.045 - 172 2 2 0 -0.0016 11 0 0 0 3.92E+08 3.42E+08 - - - 0.7508 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.17767.17767.2 0.323 14-Aug K.ISALALLK.M sp|Q92905|CSN5_HUMAN 1 827.548 1.43 4697 17767 2 827.550159 414.7813 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 8.75 3478.6 - 287154 - - - 2.5606 - 1.957 0.179 - 122.6 1 2 0 0.0021 8 0 0 0 3.23E+07 2.26E+07 - - - 2.3874 0.9854 230117_WJC_METTL3_WT_vs_EV_F01.17768.17768.2 0.328 12-Jul K.DFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 834.46 0.75 4698 17768 2 834.459024 418.2373 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.84 3478.7 - 394165 - - - -1.1133 - 1.356 0.13 - 128.4 1 2 0 -0.0009 7 0 0 0 1.72E+07 2.28E+07 - - - 0.9658 1 230117_WJC_METTL3_WT_vs_EV_F01.17770.17770.2 0.000971 20-Dec R.LLYC[160.03]TTGVLLR.R "sp|Q6P158|DHX57_HUMAN,sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 3 1307.7271 0.7 4700 17770 2 1307.727472 654.8708 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 8.22 3479 - 339425 - - - 0.2508 - 2.379 0.466 - 655.2 1 2 0 0.0003 11 0 0 0 1.04E+07 1.49E+07 - - - 4.8273 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.17771.17771.2 0.00487 18-Nov R.IAEFAFEYAR.N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1215.5924 2.42 4701 17771 2 1215.591096 608.8035 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3479.1 - 292590 - - - -1.0925 - 2.261 0.291 - 419.7 1 2 0 -0.0013 10 0 0 0 3.66E+07 1.51E+07 - - - 3.4671 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.17774.17774.2 0.851 14-Oct R.NLLTGLVR.H "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 884.5444 1.3 4702 17774 2 884.543728 443.2795 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 9.75 3479.5 - 7.57E+06 - - - -0.7043 - 1.561 0.276 - 397.1 1 2 0 -0.0006 8 0 0 0 1.86E+08 1.43E+08 - - - 2.4224 0.997 230117_WJC_METTL3_WT_vs_EV_F01.17776.17776.2 0.598 14-Nov K.ISALALLK[136.11].M sp|Q92905|CSN5_HUMAN 1 835.5622 1.43 4704 17776 2 835.561661 418.7884 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 8.75 3479.7 - 2.00E+06 - - - -0.6929 - 1.887 0.154 - 227.2 1 2 0 -0.0006 8 0 0 0 3.17E+07 2.21E+07 - - - 2.0934 0.9944 230117_WJC_METTL3_WT_vs_EV_F01.17777.17777.2 0.181 16-Jun R.LNVLANVIR[166.11].K "sp|Q02218|ODO1_HUMAN,sp|Q9ULD0|OGDHL_HUMAN,tr|E9PFG7|E9PFG7_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|A0A0D9SFS3|A0A0D9SFS3_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 6 1020.6319 0.96 4705 17777 2 1020.631678 511.3232 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 9.75 3479.8 - 1.27E+06 - - - -0.2508 - 1.559 0.15 - 96.6 2 2 0 -0.0003 9 0 0 0 1.73E+07 1.80E+07 - - - 1.299 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17779.17779.2 0.000229 20-Nov R.LLYC[160.03]TTGVLLR[166.11].R "sp|Q6P158|DHX57_HUMAN,sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 3 1317.7354 0.7 4707 17779 2 1317.73621 659.875 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 8.22 3480.1 - 1.05E+06 - - - 0.6041 - 2.067 0.449 - 513.2 1 2 0 0.0008 11 0 0 0 1.04E+07 1.49E+07 - - - 4.3213 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17781.17781.2 0.000193 18-Sep K.LLYPLQEVER.F "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 1258.6921 1 4709 17781 2 1258.695945 630.3533 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.53 3480.4 - 493986 - - - 3.0246 - 1.798 0.408 - 340.9 1 2 0 0.0038 10 0 0 0 1.06E+07 1.06E+07 - - - 3.6909 0.9934 230117_WJC_METTL3_WT_vs_EV_F01.17782.17782.2 0.0247 22-Sep R.LPVPESITGFAR.L "sp|Q8N5K1|CISD2_HUMAN,tr|I3L1N9|I3L1N9_HUMAN,tr|A0A2R8Y540|A0A2R8Y540_HUMAN" 3 1285.703 1.4 4710 17782 2 1285.706852 643.8588 CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1 6 3480.5 - 341157 - - - 2.9672 - 1.601 0.127 - 256.7 1 2 0 0.0038 12 0 0 0 5.02E+06 3.58E+06 - - - 1.2161 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.17788.17788.2 0.0142 20-Nov R.ELLIIGGVAAR[166.11].D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1120.6844 1.15 4714 17788 2 1120.686524 561.3495 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3481.3 - 780197 - - - 1.9274 - 2.131 0.372 - 342.9 1 2 0 0.0022 11 0 0 0 3.96E+08 3.45E+08 - - - 3.8347 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17791.17791.2 3.94E-06 14/22 K.TPAILYTYSGLR.N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1353.7293 2.33 4717 17791 2 1353.729947 677.8719 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3481.7 - 481546 - - - 0.5134 - 2.901 0.362 - 809.4 1 2 0 0.0007 12 0 0 0 1.64E+07 7.05E+06 - - - 4.5169 0.9877 230117_WJC_METTL3_WT_vs_EV_F01.17792.17792.2 0.716 22-Aug R.LAAQSLDTSGLR.H sp|P07199|CENPB_HUMAN 1 1230.6568 0.93 4718 17792 2 1230.658066 616.3357 Major centromere autoantigen B OS=Homo sapiens OX=9606 GN=CENPB PE=1 SV=2 5.84 3481.8 - 407450 - - - 1.0165 - 1.476 0.038 - 120 1 2 0 0.0013 12 0 0 0 1.62E+07 1.75E+07 - - - 0.3457 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17794.17794.2 0.0396 18-Sep R.LPLLAVC[160.03]DYK.Q "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1190.6369 0.72 4720 17794 2 1190.638383 596.3257 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.83 3482 - 304882 - - - 1.2187 - 2.109 0.394 - 259.5 1 2 0 0.0015 10 0 0 0 8.02E+06 1.11E+07 - - - 4.0335 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17798.17798.2 0.0056 14-Jul K.LMWIPDTK.G sp|P61962|DCAF7_HUMAN 1 1002.5208 1.83 4722 17798 2 1002.52185 502.2677 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.84 3482.6 - 1.42E+06 - - - 1.0085 - 1.46 0.422 - 221.1 1 2 0 0.001 8 0 0 0 5.83E+07 3.18E+07 - - - 3.2989 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17799.17799.2 0.000263 14-Jul K.GFGFGLVK[136.11].L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 831.4734 1.18 4723 17799 2 831.473751 416.744 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3482.6 - 748807 - - - 0.3921 - 1.555 0.407 - 159.9 1 2 0 0.0003 8 0 0 0 3.08E+08 2.60E+08 - - - 3.3785 0.8745 230117_WJC_METTL3_WT_vs_EV_F01.17802.17802.2 0.0191 14-Jul R.LLNVWQVR.S "sp|Q15061|WDR43_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 2 1026.5974 1.87 4725 17802 2 1026.587962 514.306 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 9.75 3482.9 - 6.04E+06 - - - -9.2422 - 1.679 0.302 - 149.8 1 2 0 -0.0095 8 0 0 0 8.17E+07 4.36E+07 - - - 2.8315 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.17804.17804.2 0.00423 18-Nov R.IAEFAFEYAR[166.11].N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1225.6007 2.42 4726 17804 2 1225.602111 613.8076 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3483.1 - 1.42E+06 - - - 1.1562 - 2.193 0.243 - 454.4 1 2 0 0.0014 10 0 0 0 3.66E+07 1.51E+07 - - - 3.0273 0.999 230117_WJC_METTL3_WT_vs_EV_F01.17805.17805.2 0.005 16-Sep R.LIDFLESGK.T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1020.5492 1.52 4727 17805 2 1020.549495 511.2819 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3483.2 - 2.12E+06 - - - 0.3263 - 1.438 0.345 - 166 1 2 0 0.0003 9 0 0 0 1.82E+08 1.20E+08 - - - 2.64 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.17807.17807.2 0.00235 20-Oct K.VLVIGELGVGK.T sp|Q13637|RAB32_HUMAN 1 1082.6699 1.24 4729 17807 2 1082.674551 542.3422 Ras-related protein Rab-32 OS=Homo sapiens OX=9606 GN=RAB32 PE=1 SV=3 5.97 3483.4 - 1.05E+06 - - - 4.2534 - 2.026 0.401 - 170 1 2 0 0.0046 11 0 0 0 7.09E+06 5.73E+06 - - - 3.9114 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17809.17809.2 3.42 13/22 K.TPAILYTYSGLR[166.11].N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1363.7375 2.33 4731 17809 2 1363.738618 682.876 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3483.6 - 815219 - - - 0.8037 - 2.929 0.367 - 667.9 1 2 0 0.0011 12 0 0 0 1.64E+07 7.05E+06 - - - 4.5789 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.17815.17815.2 0.354 12-Jul K.FIGELFK[136.11].L "sp|O43432|IF4G3_HUMAN,sp|Q04637|IF4G1_HUMAN,tr|A0A804HJV5|A0A804HJV5_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|A0A0U1RQK7|A0A0U1RQK7_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|A0A0A0MSA7|A0A0A0MSA7_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 11 860.4887 1.31 4735 17815 2 860.49037 431.2516 Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2 6 3484.4 - 1.69E+06 - - - 1.8931 - 1.313 0.189 - 116.5 1 2 0 0.0016 7 0 0 0 7.71E+07 5.87E+07 - - - 1.2993 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.17817.17817.2 0.0656 16-Aug K.VNIIPIIAK[136.11].A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 987.6572 1.07 4737 17817 2 987.658538 494.8359 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3484.5 - 872468 - - - 1.3517 - 1.366 0.256 - 191.4 1 2 0 0.0013 9 0 0 0 6.08E+07 5.67E+07 - - - 1.8337 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.17818.17818.2 0.00549 18-Sep K.ILETLYTLGK.A "sp|Q5W0V3|FHI2A_HUMAN,tr|Q5W0V4|Q5W0V4_HUMAN" 2 1149.6645 48.03 4738 17818 2 1149.668029 575.8395 FHF complex subunit HOOK interacting protein 2A OS=Homo sapiens OX=9606 GN=FHIP2A PE=1 SV=1 6 3484.6 - 325818 - - - 3.047 - 1.98 0.425 - 173.8 1 2 0 0.0035 10 0 0 0 9.43E+06 1.96E+05 - - - 4.0857 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.17819.17819.2 0.00647 20-Aug K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.53 4739 17819 2 1235.762834 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3484.7 - 182149 - - - 2.1655 - 1.588 0.29 - 85.7 1 2 0 0.0027 11 0 0 0 6.62E+06 4.33E+06 - - - 2.4332 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17821.17821.2 0.00344 16-Nov K.IAFAITAIK.G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 946.5852 1.2 4740 17821 2 946.58578 474.2999 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3485 - 1.81E+06 - - - 0.6613 - 2.3 0.353 - 291.8 1 2 0 0.0006 9 0 0 0 5.18E+09 4.33E+09 - - - 4.0577 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.17822.17822.2 0.109 12-Jul K.LMVPLLK.F "sp|O00410|IPO5_HUMAN,sp|O60518|RNBP6_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 3 812.5194 1.63 4741 17822 2 812.52094 407.267 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 8.75 3485.1 - 971417 - - - 1.9175 - 1.384 0.179 - 171.5 1 2 0 0.0016 7 0 0 0 2.24E+07 1.37E+07 - - - 1.3923 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.17823.17823.2 0.000522 22-Nov K.LPVGTTATLYFR.D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1337.7343 1.18 4742 17823 2 1337.733926 669.8744 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3485.2 - 594094 - - - -0.3072 - 2.134 0.394 - 323.7 1 2 0 -0.0004 12 0 0 0 1.42E+07 1.21E+07 - - - 3.9454 1 230117_WJC_METTL3_WT_vs_EV_F01.17825.17825.2 1.16E-05 14/22 K.LPVGTTATLYFR[166.11].D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1347.7426 1.16 4744 17825 2 1347.745149 674.8786 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3485.5 - 454099 - - - 1.8861 - 2.239 0.522 - 347.3 1 2 0 0.0025 12 0 0 0 1.45E+07 1.25E+07 - - - 5.0165 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.17828.17828.2 0.000499 20-Sep K.C[160.03]LYALEEGIVR.Y "sp|Q9P0M9|RM27_HUMAN,tr|H7C5U8|H7C5U8_HUMAN,tr|D6RAN8|D6RAN8_HUMAN" 3 1321.67 0.88 4747 17828 2 1321.673345 661.8423 "39S ribosomal protein L27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL27 PE=1 SV=1" 4.53 3485.9 - 156646 - - - 2.5135 - 1.705 0.341 - 164.7 1 2 0 0.0033 11 0 0 0 3.03E+06 3.44E+06 - - - 3.002 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.17831.17831.2 0.454 16-Nov K.IAFAITAIK[136.11].G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 954.5994 1.2 4749 17831 2 954.601063 478.307 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3486.3 - 1.33E+06 - - - 1.7903 - 2.266 0.223 - 229.9 1 2 0 0.0017 9 0 0 0 5.18E+09 4.33E+09 - - - 3.0541 0.9796 230117_WJC_METTL3_WT_vs_EV_F01.17833.17833.2 0.0657 14-Jun K.TILSLMTR[166.11].E sp|P53396|ACLY_HUMAN 1 943.54 1.12 4750 17833 2 943.543365 472.7773 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.41 3486.5 - 1.27E+06 - - - 3.5579 - 1.342 0.096 - 115.7 1 2 0 0.0034 8 0 0 0 5.81E+07 5.21E+07 - - - 0.6362 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.17834.17834.2 0.0289 20-Nov K.EVFSMAGVVVR[166.11].A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1202.6357 1.96 4751 17834 2 1202.635755 602.3251 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.1 3486.6 - 1.10E+06 - - - 0.0466 - 2.065 0.43 - 484.4 1 2 0 0.0001 11 0 0 0 3.17E+08 1.61E+08 - - - 4.1786 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.17835.17835.2 0.236 12-Aug K.GVIFYLR.D "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 9 866.5014 3.97 4752 17835 2 866.50203 434.258 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 8.75 3486.6 - 823138 - - - 0.6994 - 1.655 0.086 - 229 1 2 0 0.0006 7 0 0 0 6.16E+07 1.55E+07 - - - 1.2723 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.17836.17836.2 0.463 16-May R.AVDVGAFLR[166.11].D "sp|Q96BT3|CENPT_HUMAN,tr|H3BUW2|H3BUW2_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 3 956.5319 1 4753 17836 2 956.532283 479.2732 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 5.88 3486.7 - 615130 - - - 0.415 - 1.363 0.207 - 57.5 1 2 0 0.0004 9 0 0 0 4.19E+07 4.19E+07 - - - 1.4657 0.9942 230117_WJC_METTL3_WT_vs_EV_F01.17842.17842.2 0.449 14-Aug R.GLFIIDDK.G "sp|Q06830|PRDX1_HUMAN,sp|Q13162|PRDX4_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|H7C3T4|H7C3T4_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 5 919.5015 2.1 4758 17842 2 919.502335 460.758 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.21 3487.3 - 1.58E+07 - - - 0.9255 - 1.827 0.004 - 305 1 2 0 0.0009 8 0 0 0 1.82E+09 8.66E+08 - - - 0.8879 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.17845.17845.2 0.0132 16-Sep K.VNIIPIIAK.A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 979.643 1.06 4760 17845 2 979.643942 490.8288 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3487.6 - 1.35E+06 - - - 0.9585 - 1.7 0.414 - 282.7 1 2 0 0.0009 9 0 0 0 6.36E+07 6.02E+07 - - - 3.6336 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.17846.17846.2 0.0152 16-Jul K.FPTLWSGAR[166.11].S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1043.5428 1.04 4761 17846 2 1043.544751 522.7787 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 9.75 3487.6 - 1.23E+06 - - - 1.884 - 1.496 0.272 - 156.2 1 2 0 0.002 9 0 0 0 7.14E+07 6.84E+07 - - - 2.2147 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.17848.17848.2 0.239 20-Oct K.SEIEYYAMLAK[136.11].T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1324.6464 0.83 4763 17848 2 1324.651587 663.3305 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3487.9 - 204689 - - - 3.8856 - 1.749 0.199 - 361 1 2 0 0.0051 11 0 0 0 9.09E+06 1.09E+07 - - - 2.0215 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17849.17849.2 3.82E-05 20-Sep K.SEIEYYAMLAK.T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1316.6322 0.83 4764 17849 2 1316.635085 659.3234 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3488 - 166626 - - - 2.1608 - 1.855 0.521 - 196.3 1 2 0 0.0028 11 0 0 0 9.09E+06 1.09E+07 - - - 4.5597 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.17852.17852.2 0.0146 14-Aug K.GFGFGLVK.L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 823.4592 1.19 4765 17852 2 823.460115 412.7369 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3488.4 - 1.48E+07 - - - 1.0808 - 1.44 0.38 - 206.7 1 2 0 0.0009 8 0 0 0 3.11E+08 2.63E+08 - - - 2.9471 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.17853.17853.2 0.0844 16-Oct R.LAVLPYELR.F "sp|Q9ULX3|NOB1_HUMAN,tr|H3BUR4|H3BUR4_HUMAN" 2 1072.6281 1.11 4766 17853 2 1072.629947 537.3213 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 6 3488.6 - 1.79E+06 - - - 1.7397 - 2.092 0.191 - 477.9 1 2 0 0.0019 9 0 0 0 1.53E+08 1.38E+08 - - - 2.5866 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.17854.17854.2 0.802 14-Jul K.TILSLMTR.E sp|P53396|ACLY_HUMAN 1 933.5317 1.11 4767 17854 2 933.532658 467.7731 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.41 3488.6 - 4.54E+06 - - - 0.9855 - 1.281 0.315 - 164.8 1 2 0 0.0009 8 0 0 0 5.90E+07 5.33E+07 - - - 2.1142 0.9537 230117_WJC_METTL3_WT_vs_EV_F01.17856.17856.2 0.000316 14-Sep S.PLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 906.5526 1.22 4769 17856 2 906.554475 454.2836 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 10.18 3488.9 - 775312 - - - 2.0451 - 1.935 0.282 - 327.7 1 1 0 0.0019 8 0 0 0 8.07E+07 6.61E+07 - - - 3.1141 0.999 230117_WJC_METTL3_WT_vs_EV_F01.17861.17861.2 0.0182 18-Oct K.WELNPEIVAR.H sp|Q9BYD2|RM09_HUMAN 1 1225.6455 0.93 4772 17861 2 1225.649732 613.83 "39S ribosomal protein L9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL9 PE=1 SV=2" 4.53 3489.5 - 129842 - - - 3.4349 - 2.149 0.315 - 294.2 1 2 0 0.0042 10 0 0 0 5.12E+06 5.48E+06 - - - 3.5016 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.17866.17866.2 1.07 14-Aug K.IYQVLDFR.L "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1052.5655 1.54 4775 17866 2 1052.568167 527.29 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 5.84 3490.1 - 958887 - - - 2.5519 - 1.71 0.212 - 212.1 1 2 0 0.0027 8 0 0 0 4.17E+07 2.72E+07 - - - 2.224 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17868.17868.2 0.00222 12-Jun R.IIFDDFR.E sp|P46977|STT3A_HUMAN 1 924.4705 1.11 4777 17868 2 924.470865 463.2425 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.21 3490.3 - 782955 - - - 0.3753 - 1.331 0.422 - 107.2 1 2 0 0.0003 7 0 0 0 1.47E+08 1.32E+08 - - - 3.0638 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.17875.17875.2 0.0408 14-Sep K.IYQVLDFR[166.11].L "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1062.5738 2.09 4782 17875 2 1062.576119 532.2942 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 5.84 3491.1 - 1.37E+06 - - - 2.2286 - 1.736 0.296 - 306 1 2 0 0.0024 8 0 0 0 6.33E+07 3.03E+07 - - - 2.8901 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.17880.17880.2 0.0411 14-Jul R.IGLNLFNK.K "sp|Q6DN90|IQEC1_HUMAN,sp|Q5JU85|IQEC2_HUMAN,tr|A0A0C4DGT3|A0A0C4DGT3_HUMAN,tr|A0A1W2PRJ5|A0A1W2PRJ5_HUMAN,tr|A0A2R8Y7T6|A0A2R8Y7T6_HUMAN,tr|A0A6Q8PFR7|A0A6Q8PFR7_HUMAN,tr|A0A3B3IRZ4|A0A3B3IRZ4_HUMAN,tr|A0A2R8Y695|A0A2R8Y695_HUMAN,tr|A0A3B3IU98|A0A3B3IU98_HUMAN,tr|A0A1W2PR28|A0A1W2PR28_HUMAN" 10 917.5335 2.16 4785 17880 2 917.53513 459.774 IQ motif and SEC7 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=IQSEC1 PE=1 SV=1 8.75 3491.8 - 1.37E+06 - - - 1.8288 - 1.305 0.294 - 106.7 1 2 0 0.0017 8 0 0 0 2.67E+07 1.24E+07 - - - 2.0148 1 230117_WJC_METTL3_WT_vs_EV_F01.17886.17886.2 1.39E-07 26-Oct K.NVGLDIEAEVPAVK.D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1452.7824 3.09 4791 17886 2 1452.790526 727.3985 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 3492.6 - 64543 - - - 5.5865 - 2.138 0.587 - 247.3 1 2 0 0.0081 14 0 0 0 6.32E+06 2.05E+06 - - - 5.2809 0.996 230117_WJC_METTL3_WT_vs_EV_F01.17890.17890.2 0.000982 18-Sep R.AVAGWEEVLR.W "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1128.5928 0.6 4793 17890 2 1128.598838 565.3037 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 4.53 3493.1 - 878752 - - - 5.3872 - 1.803 0.367 - 192.5 1 2 0 0.0061 10 0 0 0 4.67E+06 7.79E+06 - - - 3.3951 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.17891.17891.2 0.123 14-Jul R.DILIDPIR.V "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 953.5546 1.83 4794 17891 2 953.555269 477.7846 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3493.2 - 2.02E+06 - - - 0.7205 - 1.341 0.286 - 190.8 1 2 0 0.0007 8 0 0 0 4.21E+07 2.30E+07 - - - 2.0381 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.17894.17894.2 3.55E-06 20-Nov R.YIVQVSPLGIR.L sp|Q10570|CPSF1_HUMAN 1 1243.7289 1.37 4797 17894 2 1243.730953 622.8717 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3493.5 - 813430 - - - 1.6845 - 1.885 0.375 - 482.1 1 2 0 0.0021 11 0 0 0 4.04E+07 2.96E+07 - - - 3.525 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.17895.17895.3 0.00273 Oct-40 K.LAVAHPLLLLR.H sp|Q8N201|INT1_HUMAN 1 1214.7863 1.51 4798 17895 3 1214.786674 405.936 Integrator complex subunit 1 OS=Homo sapiens OX=9606 GN=INTS1 PE=1 SV=2 9.76 3493.6 - 485035 - - - 0.2972 - 1.798 0.35 - 57.6 1 2 0 0.0004 11 0 0 0 4.88E+06 3.23E+06 - - - 4.1087 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.17899.17899.2 0.000949 20-Oct R.YIVQVSPLGIR[166.11].L sp|Q10570|CPSF1_HUMAN 1 1253.7371 1.37 4800 17899 2 1253.738101 627.8758 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3494.1 - 713479 - - - 0.7761 - 1.661 0.426 - 255.8 1 2 0 0.001 11 0 0 0 4.04E+07 2.96E+07 - - - 3.5598 0.9602 230117_WJC_METTL3_WT_vs_EV_F01.17900.17900.2 0.00366 14-Aug S.PLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 896.5444 1.23 4801 17900 2 896.546741 449.2795 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 10.18 3494.2 - 734003 - - - 2.6658 - 1.746 0.42 - 233.5 1 1 0 0.0024 8 0 0 0 8.13E+07 6.61E+07 - - - 3.8232 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.17901.17901.2 1.55 14-Sep R.IVEVLLIK.D "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 925.6212 1.16 4802 17901 2 925.621921 463.8179 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6 3494.4 - 572095 - - - 0.7735 - 1.495 0.184 - 138.3 1 2 0 0.0007 8 0 0 0 3.19E+07 2.76E+07 - - - 1.6126 0.9934 230117_WJC_METTL3_WT_vs_EV_F01.17904.17904.2 0.247 Jun-32 R.ASSGGGAGGAAGYAPVK.Y sp|P25067|CO8A2_HUMAN 1 1376.6684 2.75 4805 17904 2 1376.670305 689.3415 Collagen alpha-2(VIII) chain OS=Homo sapiens OX=9606 GN=COL8A2 PE=1 SV=2 8.63 3494.8 - 234122 - - - 1.3533 - 1.256 0.176 - 53.5 2 2 0 0.0019 17 0 0 0 2.73E+07 9.95E+06 - - - 0.7663 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.17910.17910.2 0.979 12-Jun R.ISPWLLR[166.11].V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 893.5362 0.33 4809 17910 2 893.537134 447.7754 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3495.5 - 1.91E+06 - - - 0.9972 - 1.412 0.195 - 142 1 2 0 0.0009 7 0 0 0 4.90E+07 1.50E+08 - - - 1.5742 0.998 230117_WJC_METTL3_WT_vs_EV_F01.17912.17912.2 0.0519 14-Jul R.GIFPVLC[160.03]K[136.11].D "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 940.5296 1.94 4811 17912 2 940.532559 471.2721 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 8.22 3495.8 - 716924 - - - 3.1886 - 1.591 0.268 - 153.6 1 2 0 0.003 8 0 0 0 6.62E+07 3.42E+07 - - - 2.42 0.979 230117_WJC_METTL3_WT_vs_EV_F01.17913.17913.2 4.06 20-Jun -.MSLLMISENVK.L "sp|O75449|KTNA1_HUMAN,tr|B7ZBC9|B7ZBC9_HUMAN,tr|B7ZBC8|B7ZBC8_HUMAN" 3 1263.6567 8.11 4812 17913 2 1263.659352 632.8356 Katanin p60 ATPase-containing subunit A1 OS=Homo sapiens OX=9606 GN=KATNA1 PE=1 SV=1 5.75 3495.9 - 353016 - - - 2.1137 - 1.161 0.084 - 142.9 1 2 0 0.0027 11 0 0 0 8.59E+06 1.06E+06 - - - 0.0644 0.999 230117_WJC_METTL3_WT_vs_EV_F01.17921.17921.2 0.0101 12-Aug R.ISPWLLR.V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 883.528 0.32 4818 17921 2 883.528432 442.7713 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3496.9 - 2.52E+06 - - - 0.5195 - 1.553 0.279 - 222.8 1 2 0 0.0005 7 0 0 0 4.76E+07 1.48E+08 - - - 2.4963 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17922.17922.2 0.0062 16-Oct K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 0.7 4819 17922 2 993.586312 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 3497 - 1.65E+06 - - - 1.6727 - 2.131 0.289 - 417.1 1 2 0 0.0017 9 0 0 0 1.31E+07 1.88E+07 - - - 3.3639 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.17923.17923.2 1.42 14-Sep R.IVEVLLIK[136.11].D "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 933.6354 1.16 4820 17923 2 933.635659 467.825 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6 3497.1 - 1.34E+06 - - - 0.2721 - 1.641 0.311 - 135 1 2 0 0.0003 8 0 0 0 3.09E+07 2.67E+07 - - - 2.8318 1 230117_WJC_METTL3_WT_vs_EV_F01.17924.17924.2 2.69E-07 13/22 R.VFIGNLNTALVK[136.11].K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1295.7693 0.66 4821 17924 2 1295.770639 648.8919 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3497.2 - 1.04E+06 - - - 1.0542 - 2.645 0.571 - 427.1 1 2 0 0.0014 12 0 0 0 1.14E+08 1.72E+08 - - - 5.8172 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.17925.17925.2 2.13E-05 22-Sep R.VFIGNLNTALVK.K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1287.7551 0.66 4822 17925 2 1287.761741 644.8848 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3497.3 - 1.02E+06 - - - 5.178 - 2.058 0.466 - 179.7 1 2 0 0.0067 12 0 0 0 1.14E+08 1.71E+08 - - - 4.3798 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17933.17933.2 0.00368 14-Sep K.WLTLEVC[160.03]R.E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1075.5485 1.64 4828 17933 2 1075.551324 538.7815 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3498.2 - 5.44E+06 - - - 2.6712 - 1.861 0.33 - 424.4 1 2 0 0.0029 8 0 0 0 1.27E+08 7.75E+07 - - - 3.3507 1 230117_WJC_METTL3_WT_vs_EV_F01.17934.17934.2 1.07E-05 20-Oct R.IVLLDSSLEYK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1278.7071 10.67 4829 17934 2 1278.707915 640.3608 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3498.3 - 3.55E+06 - - - 0.6225 - 2.302 0.535 - 266.4 1 2 0 0.0008 11 0 0 0 2.35E+09 2.21E+08 - - - 5.2478 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17951.17951.2 0.00478 14-Sep K.WLTLEVC[160.03]R[166.11].E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1085.5567 1.63 4844 17951 2 1085.558322 543.7856 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3500.3 - 2.18E+06 - - - 1.4748 - 1.811 0.405 - 433.5 1 2 0 0.0016 8 0 0 0 1.27E+08 7.74E+07 - - - 3.8229 0.9952 230117_WJC_METTL3_WT_vs_EV_F01.17954.17954.2 0.036 12-Jul R.YLNFFTK[136.11].A sp|P12004|PCNA_HUMAN 1 939.4946 1.42 4847 17954 2 939.493871 470.7546 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3500.6 - 890155 - - - -0.727 - 1.304 0.243 - 140.2 1 2 0 -0.0007 7 0 0 0 8.77E+07 6.17E+07 - - - 1.6766 0.9958 230117_WJC_METTL3_WT_vs_EV_F01.17955.17955.2 0.703 12-Jun R.YLNFFTK.A sp|P12004|PCNA_HUMAN 1 931.4804 1.37 4848 17955 2 931.481518 466.7475 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3500.7 - 827381 - - - 1.2496 - 1.156 0.218 - 78.7 1 2 0 0.0012 7 0 0 0 8.44E+07 6.15E+07 - - - 1.1101 1 230117_WJC_METTL3_WT_vs_EV_F01.17957.17957.2 0.000191 20-Dec K.FATEAAITILR[166.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1214.6898 11.95 4850 17957 2 1214.691933 608.3522 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3500.9 - 447000 - - - 1.7206 - 2.471 0.482 - 572.1 1 2 0 0.0021 11 0 0 0 1.83E+09 1.53E+08 - - - 5.0476 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.17962.17962.2 0.21 18-Oct K.IIQLLDDYPK[136.11].C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1224.6845 1.04 4853 17962 2 1224.68599 613.3495 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3501.6 - 948697 - - - 1.184 - 2.241 0.371 - 256 1 2 0 0.0014 10 0 0 0 5.40E+08 5.21E+08 - - - 4.0331 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.17963.17963.2 0.00239 16-Sep R.FLVQLDDYR.F "sp|Q9HAD4|WDR41_HUMAN,tr|D6RE66|D6RE66_HUMAN,tr|B4DK73|B4DK73_HUMAN,tr|D6RH33|D6RH33_HUMAN,tr|D6RA22|D6RA22_HUMAN,tr|B4DHS8|B4DHS8_HUMAN,tr|D6R9E7|D6R9E7_HUMAN,tr|H0YAA3|H0YAA3_HUMAN,tr|D6RBY6|D6RBY6_HUMAN,tr|H0YAI6|H0YAI6_HUMAN,tr|D6RB94|D6RB94_HUMAN" 11 1167.5924 1.73 4854 17963 2 1167.592868 584.8035 WD repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=WDR41 PE=1 SV=3 4.21 3501.7 - 383643 - - - 0.3803 - 1.779 0.457 - 323.7 1 2 0 0.0004 9 0 0 0 1.39E+07 8.02E+06 - - - 4.0828 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.17964.17964.2 0.0145 14-Sep K.NVFNALIR.L "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 945.5396 1.27 4855 17964 2 945.540736 473.7771 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 9.75 3501.8 - 662522 - - - 1.2014 - 1.63 0.303 - 303.8 1 2 0 0.0011 8 0 0 0 6.76E+07 5.34E+07 - - - 2.7521 0.9927 230117_WJC_METTL3_WT_vs_EV_F01.17972.17972.2 0.288 12-Aug R.WLITLNK.Q "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 886.5276 1.16 4861 17972 2 886.528839 444.2711 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 8.75 3502.7 - 3.39E+06 - - - 1.3536 - 1.401 0.079 - 290.3 1 2 0 0.0012 7 0 0 0 3.08E+08 2.64E+08 - - - 0.6925 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.17973.17973.3 0.00187 15/40 K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 10.08 4862 17973 3 1204.68313 402.5678 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3502.8 - 2.51E+06 - - - 1.2925 - 2.217 0.369 - 252.8 1 2 0 0.0016 11 0 0 0 5.60E+07 5.56E+06 - - - 4.9153 0.9549 230117_WJC_METTL3_WT_vs_EV_F01.17974.17974.2 9.91E-05 20-Dec F.ILFGVYGDVQR.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 1265.6768 1.35 4863 17974 2 1265.681048 633.8457 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 5.84 3502.9 - 1.26E+06 - - - 3.3389 - 2.042 0.473 - 581.8 1 1 0 0.0042 11 0 0 0 2.05E+07 1.52E+07 - - - 4.4646 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.17979.17979.2 0.000105 18-Nov R.LMDEAVLALR[166.11].N sp|Q92616|GCN1_HUMAN 1 1139.6248 0.67 4866 17979 2 1139.628292 570.8197 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3503.5 - 630995 - - - 3.0642 - 1.958 0.442 - 402.9 1 2 0 0.0035 10 0 0 0 1.47E+07 2.19E+07 - - - 4.1801 0.9928 230117_WJC_METTL3_WT_vs_EV_F01.17982.17982.2 0.175 18-Jul K.LQVLVGDVLK[136.11].T "sp|Q9UNQ2|DIM1_HUMAN,tr|A0A494C0G7|A0A494C0G7_HUMAN,tr|B4DRY2|B4DRY2_HUMAN,tr|A0A0C4DGB1|A0A0C4DGB1_HUMAN,tr|A0A7P0T9J1|A0A7P0T9J1_HUMAN,tr|A0A7P0Z4I0|A0A7P0Z4I0_HUMAN,tr|A0A7P0T9Y7|A0A7P0T9Y7_HUMAN,tr|D6RCL3|D6RCL3_HUMAN" 8 1090.6841 0.61 4868 17982 2 1090.685374 546.3493 Probable dimethyladenosine transferase OS=Homo sapiens OX=9606 GN=DIMT1 PE=1 SV=1 5.84 3503.8 - 1.78E+06 - - - 1.1259 - 1.473 0.08 - 99.9 1 2 0 0.0012 10 0 0 0 8.82E+06 1.45E+07 - - - 0.7126 0.8657 230117_WJC_METTL3_WT_vs_EV_F01.17985.17985.2 1.15 22-Jun R.IIYVPLPDAATR.R "sp|Q8NB90|AFG2H_HUMAN,tr|A0A6Q8PGU6|A0A6Q8PGU6_HUMAN" 2 1327.75 6.11 4871 17985 2 1327.743511 664.8823 ATPase family protein 2 homolog OS=Homo sapiens OX=9606 GN=SPATA5 PE=1 SV=3 5.84 3504.2 - 423522 - - - -4.8774 - 1.488 0.158 - 101 4 2 0 -0.0065 12 0 0 0 6.26E+06 1.02E+06 - - - 0.9827 0.994 230117_WJC_METTL3_WT_vs_EV_F01.17987.17987.2 0.0343 20-Jul K.VLLQSALSLGR.S "sp|Q96T51|RUFY1_HUMAN,tr|H0Y9Y8|H0Y9Y8_HUMAN,tr|J3KPP6|J3KPP6_HUMAN" 3 1155.6976 1.69 4873 17987 2 1155.702434 578.8561 RUN and FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RUFY1 PE=1 SV=2 9.72 3504.4 - 301301 - - - 4.2191 - 1.435 0.268 - 102.3 1 2 0 0.0049 11 0 0 0 4.15E+06 2.46E+06 - - - 1.996 1 230117_WJC_METTL3_WT_vs_EV_F01.17991.17991.2 2.38E-05 18-Nov K.IIQLLDDYPK.C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1216.6703 1.04 4875 17991 2 1216.670311 609.3424 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3505 - 7.60E+06 - - - -0.0238 - 2.339 0.536 - 414.1 1 2 0 0 10 0 0 0 5.40E+08 5.21E+08 - - - 5.3717 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.17994.17994.2 0.0231 14-Jun R.AFFSSYLK[136.11].S "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 969.5051 0.87 4878 17994 2 969.507027 485.7598 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.63 3505.3 - 750298 - - - 1.968 - 1.162 0.259 - 89.8 1 2 0 0.0019 8 0 0 0 2.74E+07 3.15E+07 - - - 1.4062 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.17997.17997.2 0.000706 18-Jul R.LMDEAVLALR.N sp|Q92616|GCN1_HUMAN 1 1129.6165 0.72 4881 17997 2 1129.619344 565.8155 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3505.7 - 444251 - - - 2.4911 - 1.792 0.437 - 128.5 1 2 0 0.0028 10 0 0 0 1.68E+07 2.34E+07 - - - 3.8961 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18011.18011.2 0.0297 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 3189.24 4892 18011 2 1006.571272 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3507.4 - 2.39E+06 - - - 1.365 - 1.83 0.444 - 242.3 1 2 0 0.0014 9 0 0 0 1.92E+08 6.03E+04 - - - 4.0683 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.18012.18012.2 0.0045 14-Jul R.AFFSSYLK.S "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 961.4909 0.87 4893 18012 2 961.491945 481.7527 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.63 3507.5 - 1.35E+06 - - - 1.0671 - 1.329 0.364 - 142 1 2 0 0.001 8 0 0 0 2.74E+07 3.15E+07 - - - 2.587 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.18014.18014.2 0.102 14-Jul R.NILIVLTK[136.11].L "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN,tr|H0Y815|H0Y815_HUMAN" 3 920.615 0.81 4895 18014 2 920.614885 461.3148 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 8.75 3507.7 - 356434 - - - -0.1293 - 1.29 0.333 - 116.7 1 2 0 -0.0001 8 0 0 0 1.13E+07 1.39E+07 - - - 2.2685 0.996 230117_WJC_METTL3_WT_vs_EV_F01.18021.18021.2 0.00425 20-Nov R.YGLIGLNGIGK[136.11].S "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1111.6481 3.35 4900 18021 2 1111.645256 556.8313 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.59 3508.5 - 873864 - - - -2.5539 - 2.004 0.293 - 220.3 1 2 0 -0.0028 11 0 0 0 1.26E+08 3.75E+07 - - - 3.0847 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.18022.18022.2 0.0003 16-Aug K.AENPYLFLR.G "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN" 2 1121.5869 1.46 4901 18022 2 1121.586439 561.8007 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 6.05 3508.6 - 811923 - - - -0.4511 - 1.694 0.328 - 202 1 2 0 -0.0005 9 0 0 0 1.14E+07 7.81E+06 - - - 2.9884 0.9903 230117_WJC_METTL3_WT_vs_EV_F01.18026.18026.2 3.93 14-Jul R.TLIEELPS.- sp|Q9UHR6|ZNHI2_HUMAN 1 900.4804 - 4903 18026 2 900.479958 451.2475 Zinc finger HIT domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZNHIT2 PE=1 SV=1 3.79 3509.1 - 781906 - - - -0.5064 - 1.166 0.201 - 119.3 1 2 0 -0.0005 8 0 0 0 - - - - - 0.9886 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18029.18029.2 0.00874 14-Sep R.LSVLLGLK.K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 841.5637 2.25 4905 18029 2 841.565375 421.7891 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3509.5 - 532212 - - - 2.0022 - 2.022 0.339 - 201.5 1 2 0 0.0017 8 0 0 0 1.19E+07 5.28E+06 - - - 3.6678 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.18031.18031.2 0.00841 16-Aug K.AAIDWFDGK.E "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1021.4869 1.06 4907 18031 2 1021.491323 511.7507 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.21 3509.7 - 523320 - - - 4.3339 - 1.808 0.391 - 153.3 1 2 0 0.0044 9 0 0 0 7.36E+06 6.96E+06 - - - 3.6409 0.999 230117_WJC_METTL3_WT_vs_EV_F01.18034.18034.2 0.0298 18-Sep K.SFIMSSTLIR.H sp|Q9UEG4|ZN629_HUMAN 1 1153.6165 1.33 4910 18034 2 1153.617607 577.8155 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.47 3510.1 - 443583 - - - 0.9336 - 1.428 0.327 - 188.4 1 2 0 0.0011 10 0 0 0 9.38E+06 7.04E+06 - - - 2.4504 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.18035.18035.2 0.252 14-Jun R.FLLETVVR.V "sp|Q5R372|RBG1L_HUMAN,tr|A0A0U1RRM5|A0A0U1RRM5_HUMAN,tr|A0A0C4DG54|A0A0C4DG54_HUMAN,tr|A0A804HKD7|A0A804HKD7_HUMAN" 4 975.5753 0.44 4911 18035 2 975.576065 488.7949 Rab GTPase-activating protein 1-like OS=Homo sapiens OX=9606 GN=RABGAP1L PE=1 SV=1 6 3510.3 - 347047 - - - 0.7667 - 1.304 0.188 - 84.9 1 2 0 0.0007 8 0 0 0 6.87E+06 1.56E+07 - - - 1.2299 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18040.18040.2 1.02E-06 20-Oct R.IVLLDSSLEYK[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1286.7213 10.66 4915 18040 2 1286.723033 644.3679 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3510.9 - 6.16E+06 - - - 1.3321 - 2.345 0.326 - 276.9 1 2 0 0.0017 11 0 0 0 2.35E+09 2.21E+08 - - - 3.7539 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18042.18042.2 0.04 20-Sep R.YGLIGLNGIGK.S "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1103.6339 2.69 4916 18042 2 1103.635721 552.8242 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.59 3511.1 - 7.66E+06 - - - 1.6545 - 1.865 0.322 - 164.6 1 2 0 0.0018 11 0 0 0 9.47E+07 3.52E+07 - - - 3.1048 0.9838 230117_WJC_METTL3_WT_vs_EV_F01.18044.18044.2 0.331 20-May K.LPVVISQC[160.03]GEM.- "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1231.5941 - 4918 18044 2 1231.596681 616.8043 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4 3511.2 - 2.15E+06 - - - 2.1119 - 0.923 0.21 - 51.7 2 2 0 0.0026 11 0 0 0 - - - - - 0.24 1 230117_WJC_METTL3_WT_vs_EV_F01.18045.18045.2 1.27E-07 18-Nov R.EC[160.03]LNLWGYER.V sp|Q86U44|MTA70_HUMAN 1 1338.6027 21.55 4919 18045 2 1338.606096 670.3086 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3511.3 - 1.58E+06 - - - 2.5586 - 2.162 0.568 - 672.2 1 2 0 0.0034 10 0 0 0 8.34E+07 3.87E+06 - - - 5.3874 0.998 230117_WJC_METTL3_WT_vs_EV_F01.18049.18049.2 0.0209 16-Jul K.NFDMVIVYK[136.11].D sp|Q9Y5B9|SP16H_HUMAN 1 1135.5827 1.03 4923 18049 2 1135.584356 568.7986 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.83 3511.7 - 858054 - - - 1.4433 - 1.317 0.257 - 117.5 1 2 0 0.0016 9 0 0 0 9.23E+06 8.95E+06 - - - 1.7353 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18055.18055.2 0.0217 18-Sep R.FLLADNLYC[160.03]K.A sp|P61758|PFD3_HUMAN 1 1255.6271 3.62 4927 18055 2 1255.630632 628.8208 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 5.83 3512.4 - 2.13E+06 - - - 2.8169 - 1.972 0.378 - 200.7 1 2 0 0.0035 10 0 0 0 5.97E+07 1.65E+07 - - - 3.7272 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18057.18057.2 0.000613 16-Jul K.NFDMVIVYK.D sp|Q9Y5B9|SP16H_HUMAN 1 1127.5685 0.95 4929 18057 2 1127.570021 564.7915 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.83 3512.5 - 708667 - - - 1.3338 - 1.58 0.439 - 141.6 1 2 0 0.0015 9 0 0 0 9.21E+06 9.65E+06 - - - 3.6063 0.9947 230117_WJC_METTL3_WT_vs_EV_F01.18059.18059.2 0.0198 24-Jul R.LPLLPPESPGPLR[166.11].Q "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN,tr|A0A669KAX5|A0A669KAX5_HUMAN" 6 1394.8161 3.86 4931 18059 2 1394.816888 698.4153 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 6 3512.8 - 129513 - - - 0.5606 - 1.554 0.134 - 110.5 2 2 0 0.0008 13 0 0 0 5.57E+06 1.44E+06 - - - 1.0274 1 230117_WJC_METTL3_WT_vs_EV_F01.18063.18063.2 2.88E-06 18-Oct K.VEDAMLMFDK.T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|A0A6Q8PHP1|A0A6Q8PHP1_HUMAN" 6 1197.541 4.32 4933 18063 2 1197.544611 599.7778 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.03 3513.2 - 1.15E+06 - - - 3.0304 - 2.202 0.559 - 380.8 1 2 0 0.0036 10 0 0 0 2.80E+07 6.48E+06 - - - 5.372 1 230117_WJC_METTL3_WT_vs_EV_F01.18064.18064.2 2.44E-06 18-Nov K.VDDAMLMFDK.T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1183.5253 1.41 4934 18064 2 1183.528738 592.7699 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 3.93 3513.3 - 1.20E+06 - - - 2.8778 - 2.045 0.601 - 386.1 1 2 0 0.0034 10 0 0 0 4.76E+07 3.39E+07 - - - 5.4758 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18065.18065.2 0.0293 18-Nov K.VDDAMLMFDK[136.11].T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1191.5395 1.4 4935 18065 2 1191.538993 596.777 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 3.93 3513.4 - 949507 - - - -0.4524 - 2.506 0.273 - 424.2 1 2 0 -0.0005 10 0 0 0 4.75E+07 3.39E+07 - - - 3.6215 0.9543 230117_WJC_METTL3_WT_vs_EV_F01.18066.18066.2 0.0955 14-Sep K.LASFFLSR.V "sp|Q8IZL8|PELP1_HUMAN,tr|E7EV54|E7EV54_HUMAN,tr|C9JFV4|C9JFV4_HUMAN,tr|I3L4P1|I3L4P1_HUMAN,tr|I3L445|I3L445_HUMAN" 5 939.5178 0.48 4936 18066 2 939.525672 470.7662 "Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2" 9.75 3513.4 - 698776 - - - 8.3766 - 1.605 0.262 - 243.2 1 2 0 0.0079 8 0 0 0 7.08E+06 1.47E+07 - - - 2.4006 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.18067.18067.2 3.19E-05 18-Sep R.FGFGFGNGMK[136.11].Q "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 8 1068.4942 0.6 4937 18067 2 1068.498316 535.2544 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 8.75 3513.5 - 582627 - - - 3.8175 - 1.738 0.531 - 120.3 1 2 0 0.0041 10 0 0 0 5.47E+06 9.16E+06 - - - 4.5045 0.998 230117_WJC_METTL3_WT_vs_EV_F01.18071.18071.2 0.03 20-Oct R.C[160.03]LAPMMSEVIR.L "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 1305.6243 1.17 4941 18071 2 1305.628586 653.8194 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 5.99 3513.9 - 206098 - - - 3.2559 - 1.653 0.281 - 295.3 1 2 0 0.0043 11 0 0 0 2.82E+06 2.41E+06 - - - 2.4748 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.18073.18073.2 0.000481 28-Sep R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 9.46 4943 18073 2 1494.920696 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3514.2 - 102892 - - - 3.0376 - 1.781 0.396 - 177.2 1 2 0 0.0045 15 0 0 0 2.04E+07 2.16E+06 - - - 3.3834 0.9969 230117_WJC_METTL3_WT_vs_EV_F01.18077.18077.2 0.0184 14-Aug R.ADLIAYLK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 905.5222 1.76 4945 18077 2 905.524088 453.7684 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 5.88 3514.7 - 1.57E+06 - - - 2.064 - 1.482 0.166 - 155.4 1 2 0 0.0019 8 0 0 0 3.44E+07 1.95E+07 - - - 1.4529 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.18079.18079.2 0.000484 20-Aug R.AVVPSYIPLVK[136.11].K sp|P36551|HEM6_HUMAN 1 1192.7311 1.08 4947 18079 2 1192.734871 597.3728 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3514.8 - 2.49E+06 - - - 3.165 - 1.604 0.369 - 222.8 1 2 0 0.0038 11 0 0 0 2.07E+08 1.92E+08 - - - 3.0435 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.18080.18080.2 1.02E-05 20-Oct R.AVVPSYIPLVK.K sp|P36551|HEM6_HUMAN 1 1184.7169 1.08 4948 18080 2 1184.720909 593.3657 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3514.9 - 2.27E+06 - - - 3.3873 - 1.741 0.422 - 384.5 1 2 0 0.004 11 0 0 0 2.07E+08 1.92E+08 - - - 3.6566 1 230117_WJC_METTL3_WT_vs_EV_F01.18082.18082.2 2.04E-05 14/24 K.VLATTFDPYLGGR.N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1408.7351 12.58 4950 18082 2 1408.738233 705.3748 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3515.1 - 1.28E+06 - - - 2.2488 - 2.66 0.505 - 540 1 2 0 0.0032 13 0 0 0 6.68E+07 5.31E+06 - - - 5.2808 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18085.18085.2 0.127 18-Nov K.EVLLVALGSR.Q sp|Q10570|CPSF1_HUMAN 1 1055.6339 1.6 4953 18085 2 1055.636328 528.8242 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6.1 3515.5 - 707199 - - - 2.3048 - 2.348 0.29 - 368.6 1 2 0 0.0024 10 0 0 0 1.24E+07 7.74E+06 - - - 3.5647 0.9098 230117_WJC_METTL3_WT_vs_EV_F01.18086.18086.2 0.00116 20-Jul R.LVHPGVAEVVF.V "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1165.6495 - 4954 18086 2 1165.653184 583.832 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.24 3515.6 - 693423 - - - 3.1219 - 1.62 0.348 - 138.7 1 1 0 0.0036 11 0 0 0 - - - - - 2.9153 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.18087.18087.2 8.38E-05 28-Nov R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 5.3 4955 18087 2 1484.913477 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3515.7 - 618546 - - - 3.7659 - 2.21 0.487 - 297.6 1 2 0 0.0056 15 0 0 0 6.33E+06 1.19E+06 - - - 4.5858 1 230117_WJC_METTL3_WT_vs_EV_F01.18089.18089.2 2.47E-10 13/30 K.VLAQNSGFDLQETLVK.L sp|P40227|TCPZ_HUMAN 1 1760.9309 999 4957 18089 2 1760.93438 881.4727 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3516 - 327037 - - - 1.9961 - 2.952 0.513 - 513.8 1 2 0 0.0035 16 0 0 0 3.05E+06 0.00E+00 - - - 5.4902 0.9868 230117_WJC_METTL3_WT_vs_EV_F01.18090.18090.2 0.282 24-Sep R.LPLLPPESPGPLR.Q "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN,tr|A0A669KAX5|A0A669KAX5_HUMAN" 6 1384.8078 3.86 4958 18090 2 1384.81604 693.4112 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 6 3516.1 - 316958 - - - 5.9243 - 1.933 0.222 - 227 1 2 0 0.0082 13 0 0 0 5.57E+06 1.44E+06 - - - 2.3696 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.18097.18097.2 0.0158 14-Aug R.LDTIFFAK.Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 953.5222 2.42 4963 18097 2 953.525617 477.7684 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3517 - 1.90E+07 - - - 3.5636 - 1.714 0.32 - 188.2 1 2 0 0.0034 8 0 0 0 1.78E+08 7.37E+07 - - - 3.0285 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.18098.18098.2 0.0138 14-Jul R.LDTIFFAK[136.11].Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 961.5364 2.42 4964 18098 2 961.539206 481.7755 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3517 - 9.66E+06 - - - 2.8985 - 1.644 0.257 - 136.6 1 2 0 0.0028 8 0 0 0 1.78E+08 7.37E+07 - - - 2.4377 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18101.18101.2 0.000203 16-Aug R.FLSPEFIPR[166.11].R "sp|P49406|RM19_HUMAN,tr|A0A0A0MRF4|A0A0A0MRF4_HUMAN" 2 1114.6051 0.49 4967 18101 2 1114.607616 558.3098 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 6 3517.2 - 2.72E+06 - - - 2.3013 - 1.717 0.404 - 218.8 1 2 0 0.0026 9 0 0 0 1.89E+07 3.88E+07 - - - 3.5881 0.9903 230117_WJC_METTL3_WT_vs_EV_F01.18102.18102.2 0.708 14-Jun R.GIFEPFGR.L "sp|Q14498|RBM39_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 5 921.4709 0.58 4968 18102 2 921.473018 461.7427 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 6 3517.3 - 1.85E+06 - - - 2.3506 - 1.371 0.091 - 96.1 1 2 0 0.0022 8 0 0 0 8.17E+07 1.40E+08 - - - 0.6641 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18103.18103.2 0.0158 14-Sep K.NILTEIYR.L sp|Q15907|RB11B_HUMAN 1 1020.5604 1.8 4969 18103 2 1020.563052 511.2875 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 6 3517.3 - 1.65E+06 - - - 2.6035 - 1.712 0.39 - 303.1 1 2 0 0.0027 8 0 0 0 5.10E+07 2.83E+07 - - - 3.5423 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.18104.18104.2 0.801 14-Aug K.ILILQGLK.Q "sp|Q9UNX4|WDR3_HUMAN,tr|D6RCT0|D6RCT0_HUMAN" 2 896.6059 0.98 4970 18104 2 896.60763 449.3102 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 8.75 3517.4 - 1.47E+06 - - - 1.9418 - 1.679 0.179 - 167.8 1 2 0 0.0017 8 0 0 0 2.54E+07 2.58E+07 - - - 1.9254 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.18109.18109.2 1.24E-05 24-Oct K.VLATTFDPYLGGR[166.11].N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1418.7433 12.52 4975 18109 2 1418.749932 710.3789 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3518 - 397088 - - - 4.6499 - 2.093 0.443 - 221.4 1 2 0 0.0066 13 0 0 0 6.64E+07 5.31E+06 - - - 4.2066 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18112.18112.2 0.0176 16-Sep R.AVALYFIDK[136.11].L "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN,tr|E5RIC7|E5RIC7_HUMAN" 4 1046.5892 1.39 4977 18112 2 1046.591846 524.3019 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 5.88 3518.3 - 6.46E+06 - - - 2.5445 - 1.93 0.378 - 286.1 1 2 0 0.0027 9 0 0 0 5.92E+07 4.26E+07 - - - 3.7343 0.9959 230117_WJC_METTL3_WT_vs_EV_F01.18114.18114.2 0.0193 14-Sep K.NILTEIYR[166.11].L sp|Q15907|RB11B_HUMAN 1 1030.5687 1.75 4978 18114 2 1030.573538 516.2916 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 6 3518.5 - 1.96E+06 - - - 4.7285 - 1.781 0.269 - 299 1 2 0 0.0049 8 0 0 0 4.91E+07 2.81E+07 - - - 2.767 0.997 230117_WJC_METTL3_WT_vs_EV_F01.18119.18119.2 0.000651 18-Oct K.VLALLDVPDK[136.11].S sp|Q9NX62|IMPA3_HUMAN 1 1089.6525 1.06 4983 18119 2 1089.6566 545.8335 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.21 3518.9 - 1.39E+06 - - - 3.7526 - 2.02 0.187 - 277.3 1 2 0 0.0041 10 0 0 0 5.95E+07 5.60E+07 - - - 2.3835 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18123.18123.2 0.0125 18-Oct R.LITTQQWLIK[136.11].L sp|P00846|ATP6_HUMAN 1 1250.7478 0.96 4987 18123 2 1250.750671 626.3812 ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1 8.75 3519.4 - 472700 - - - 2.2882 - 1.94 0.437 - 229.3 1 2 0 0.0029 10 0 0 0 9.07E+06 9.44E+06 - - - 4.1175 1 230117_WJC_METTL3_WT_vs_EV_F01.18126.18126.2 7.71E-12 15/38 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 6.74 4990 18126 2 2187.047933 1094.5262 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3519.8 - 233849 - - - 4.603 - 3.299 0.701 - 597.4 1 2 0 0.0101 20 0 0 0 5.46E+06 8.10E+05 - - - 7.15 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18135.18135.2 0.00205 18-Sep R.IC[160.03]DDELILIK.N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1230.653 9.69 4997 18135 2 1230.655672 616.3338 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3521 - 7.98E+06 - - - 2.1907 - 1.816 0.302 - 174.7 1 2 0 0.0027 10 0 0 0 1.22E+09 1.26E+08 - - - 2.9361 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.18138.18138.2 0.00285 20-Sep R.LLALNSLYSPK.L sp|P78527|PRKDC_HUMAN 1 1217.702 1.33 5000 18138 2 1217.705658 609.8583 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.59 3521.1 - 1.46E+06 - - - 3.0254 - 1.963 0.322 - 213 1 2 0 0.0037 11 0 0 0 8.41E+07 6.31E+07 - - - 3.2427 1 230117_WJC_METTL3_WT_vs_EV_F01.18140.18140.2 7.21E-06 13/18 R.IC[160.03]DDELILIK[136.11].N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1238.6672 9.7 5002 18140 2 1238.669988 620.3409 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3521.3 - 920653 - - - 2.2702 - 2.798 0.393 - 395.6 1 2 0 0.0028 10 0 0 0 1.22E+09 1.26E+08 - - - 4.8148 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.18142.18142.2 0.00373 16-Aug K.IIGNLLYYR.Y "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1123.639 1.15 5004 18142 2 1123.64332 562.8268 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.59 3521.5 - 629252 - - - 3.8625 - 1.893 0.362 - 117.3 1 2 0 0.0043 9 0 0 0 5.03E+07 4.36E+07 - - - 3.5596 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18144.18144.2 1.44E-05 22-Dec R.IGPLSPFTNAYR[166.11].R "sp|O75486|SUPT3_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 2 1344.7066 1.74 5006 18144 2 1344.711317 673.3606 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 8.75 3521.7 - 483527 - - - 3.5405 - 2.179 0.464 - 311.9 1 2 0 0.0048 12 0 0 0 2.13E+07 1.23E+07 - - - 4.5159 0.9892 230117_WJC_METTL3_WT_vs_EV_F01.18145.18145.3 0.325 Jul-40 R.AVVPSYIPLVK[136.11].K sp|P36551|HEM6_HUMAN 1 1192.7311 1.05 5007 18145 3 1192.733225 398.5843 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3521.8 - 291574 - - - 1.785 - 1.407 0.175 - 47.4 1 2 0 0.0021 11 0 0 0 3.19E+06 3.03E+06 - - - 1.4605 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18147.18147.2 0.000337 28-Aug R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 9.46 5009 18147 2 1494.915513 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3522.1 - 81773.8 - - - -0.4295 - 1.848 0.44 - 160.3 1 2 0 -0.0006 15 0 0 0 2.04E+07 2.16E+06 - - - 3.8004 0.9947 230117_WJC_METTL3_WT_vs_EV_F01.18150.18150.2 0.0473 14-Aug K.IDHILDAL.- "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 908.4967 - 5010 18150 2 908.499769 455.2556 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.2 3522.5 - 3.16E+06 - - - 3.3418 - 1.537 0.168 - 168.2 1 2 0 0.003 8 0 0 0 - - - - - 1.5772 1 230117_WJC_METTL3_WT_vs_EV_F01.18152.18152.3 2.21E-11 17/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 4.01 5012 18152 3 2187.047233 730.0199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3522.7 - 984008 - - - 4.283 - 3.358 0.656 - 271.9 1 2 0 0.0094 20 0 0 0 8.70E+06 2.17E+06 - - - 8.7899 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18153.18153.2 0.00382 20-Nov K.VLTPELYAELR.A "sp|P12277|KCRB_HUMAN,tr|G3V461|G3V461_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 3 1302.7184 0.87 5013 18153 2 1302.722304 652.3665 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.53 3522.8 - 801789 - - - 3.0329 - 2.423 0.386 - 523.7 1 2 0 0.004 11 0 0 0 7.32E+07 8.45E+07 - - - 4.2849 0.9905 230117_WJC_METTL3_WT_vs_EV_F01.18158.18158.2 0.483 12-Aug K.FLELLPK.D "sp|P63010|AP2B1_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 5 858.5215 1.61 5018 18158 2 858.524463 430.268 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 6 3523.5 - 379630 - - - 3.4618 - 1.23 0.199 - 162.6 1 2 0 0.003 7 0 0 0 3.95E+07 2.44E+07 - - - 1.1658 0.983 230117_WJC_METTL3_WT_vs_EV_F01.18162.18162.2 0.264 14-Aug R.DVDFELIK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 985.5212 5.16 5020 18162 2 985.525764 493.7679 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3524 - 4.42E+06 - - - 4.6686 - 1.27 0.215 - 165.6 1 2 0 0.0046 8 0 0 0 9.49E+08 1.84E+08 - - - 1.3484 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.18165.18165.2 0.00983 16-Oct R.SSIAGLLLK.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 900.5644 4.5 5023 18165 2 900.567545 451.2895 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.47 3524.3 - 1.97E+06 - - - 3.4723 - 1.779 0.307 - 207.9 1 2 0 0.0031 9 0 0 0 4.26E+07 9.47E+06 - - - 2.9741 0.998 230117_WJC_METTL3_WT_vs_EV_F01.18167.18167.2 0.00868 16-Dec R.LGIQLDFEK.N "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1061.5757 4.28 5025 18167 2 1061.580243 531.7951 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.37 3524.5 - 1.26E+06 - - - 4.2691 - 2.167 0.275 - 321.1 1 2 0 0.0045 9 0 0 0 1.10E+07 2.57E+06 - - - 3.3081 0.9575 230117_WJC_METTL3_WT_vs_EV_F01.18180.18180.2 0.00561 16-Jul K.TVTAMDVVY.A sp|P62805|H4_HUMAN 1 997.479 - 5036 18180 2 997.480569 499.7468 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 3.8 3526 - 5.98E+06 - - - 1.5389 - 1.341 0.432 - 130.1 1 1 0 0.0015 9 0 0 0 - - - - - 3.0801 1 230117_WJC_METTL3_WT_vs_EV_F01.18182.18182.2 5.10E-05 18-Oct R.VVYIFGPPVK.E sp|P49915|GUAA_HUMAN 1 1117.6536 4.74 5038 18182 2 1117.655355 559.8341 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 8.56 3526.1 - 869491 - - - 1.5989 - 2.1 0.472 - 422.6 1 2 0 0.0018 10 0 0 0 2.23E+07 4.70E+06 - - - 4.5976 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.18190.18190.2 0.00342 14-Sep R.LFGALLER[166.11].G sp|Q9BVI4|NOC4L_HUMAN 1 927.5417 1.1 5044 18190 2 927.543478 464.7781 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3527 - 1.14E+07 - - - 1.8932 - 1.993 0.214 - 291.3 1 2 0 0.0018 8 0 0 0 2.11E+08 1.92E+08 - - - 2.701 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.18194.18194.3 0.013 15/36 R.FSVLLLHGIR.F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1153.6972 2.73 5048 18194 3 1153.698416 385.573 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3527.4 - 2.11E+06 - - - 1.0852 - 2.408 0.425 - 262.3 1 2 0 0.0013 10 0 0 0 1.89E+07 6.95E+06 - - - 5.8445 0.9877 230117_WJC_METTL3_WT_vs_EV_F01.18196.18196.2 0.339 14-Jul R.LYPVLLVK[136.11].Q "sp|Q7Z7F7|RM55_HUMAN,tr|X6RIW1|X6RIW1_HUMAN" 2 951.6248 1.06 5050 18196 2 951.626621 476.8197 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 8.59 3527.5 - 1.37E+06 - - - 1.8715 - 0.903 0.222 - 121.7 1 2 0 0.0018 8 0 0 0 3.07E+07 2.89E+07 - - - 0.3724 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18198.18198.2 4.33E-05 22-Nov R.LLQTIAVLEAQR.S sp|Q8IYH5|ZZZ3_HUMAN 1 1353.798 3.93 5052 18198 2 1353.798837 677.9063 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 6 3527.8 - 951553 - - - 0.6183 - 2.364 0.36 - 486.2 1 2 0 0.0008 12 0 0 0 6.20E+06 1.57E+06 - - - 3.9634 1 230117_WJC_METTL3_WT_vs_EV_F01.18200.18200.2 0.000169 22-Nov K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 17.44 5054 18200 2 1474.74595 738.3781 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3528 - 737737 - - - 2.9449 - 2.557 0.515 - 448.1 1 2 0 0.0043 12 0 0 0 9.17E+06 5.26E+05 - - - 5.3137 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18201.18201.2 7.83E-05 20-Oct R.LLMLGLDNAGK.T "sp|P36404|ARL2_HUMAN,tr|V9GYD0|V9GYD0_HUMAN" 2 1143.6322 2.32 5055 18201 2 1143.635304 572.8234 ADP-ribosylation factor-like protein 2 OS=Homo sapiens OX=9606 GN=ARL2 PE=1 SV=4 5.84 3528.1 - 650950 - - - 2.7316 - 1.888 0.411 - 208.3 1 2 0 0.0031 11 0 0 0 5.81E+06 2.50E+06 - - - 3.7949 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18202.18202.3 0.217 13/36 R.FSVLLLHGIR[166.11].F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1163.7054 2.64 5056 18202 3 1163.704743 388.9091 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3528.2 - 609065 - - - -0.5938 - 2.44 0.279 - 154.9 1 2 0 -0.0007 10 0 0 0 1.91E+07 7.23E+06 - - - 4.2554 1 230117_WJC_METTL3_WT_vs_EV_F01.18203.18203.2 8.04E-08 20-Nov R.FPC[160.03]VVYINEVR.V sp|Q69YN4|VIR_HUMAN 1 1394.7017 3.95 5057 18203 2 1394.699835 698.3581 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 5.99 3528.3 - 470387 - - - -1.3064 - 2.364 0.502 - 598.5 1 2 0 -0.0018 11 0 0 0 6.23E+06 1.58E+06 - - - 5.0757 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.18207.18207.2 0.486 18-Sep K.VLALLDVPDK.S sp|Q9NX62|IMPA3_HUMAN 1 1081.6383 0.97 5060 18207 2 1081.639066 541.8264 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.21 3528.8 - 1.84E+06 - - - 0.698 - 2.006 0.189 - 241.5 1 2 0 0.0008 10 0 0 0 5.45E+07 5.60E+07 - - - 2.3799 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18209.18209.2 0.00871 14-Aug R.LFGALLER.G sp|Q9BVI4|NOC4L_HUMAN 1 917.5335 1.04 5061 18209 2 917.535664 459.774 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3529 - 1.96E+06 - - - 2.4108 - 1.86 0.289 - 213 1 2 0 0.0022 8 0 0 0 2.22E+08 2.14E+08 - - - 3.0465 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.18210.18210.2 5.08 12-Aug R.LLDFLQK.R "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 875.5117 1.35 5062 18210 2 875.513785 438.7631 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.84 3529.1 - 880980 - - - 2.434 - 1.61 0.103 - 156.5 1 2 0 0.0021 7 0 0 0 1.12E+08 8.31E+07 - - - 1.3101 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.18215.18215.2 0.014 14-Jul K.TFIFLNAK[136.11].Q "sp|O60934|NBN_HUMAN,tr|A0A0C4DG07|A0A0C4DG07_HUMAN,tr|E5RGR7|E5RGR7_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 4 960.5524 1.15 5067 18215 2 960.554691 481.2835 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 8.41 3529.4 - 302205 - - - 2.382 - 1.24 0.358 - 104.6 1 2 0 0.0023 8 0 0 0 1.23E+07 1.06E+07 - - - 2.3332 0.9942 230117_WJC_METTL3_WT_vs_EV_F01.18219.18219.2 4.41 14-Sep K.IISLDAWR.V "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 972.5393 1.73 5069 18219 2 972.543205 487.2769 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.84 3530 - 553849 - - - 4.0502 - 1.814 0.147 - 169.5 1 2 0 0.0039 8 0 0 0 4.13E+07 2.39E+07 - - - 1.9216 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18220.18220.2 0.00122 16-Sep R.VVLPYLVPK.L sp|Q92616|GCN1_HUMAN 1 1026.6478 1.18 5070 18220 2 1026.64962 514.3312 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.56 3530.1 - 956480 - - - 1.8176 - 1.595 0.381 - 243 1 2 0 0.0019 9 0 0 0 6.21E+07 5.28E+07 - - - 3.2052 0.9906 230117_WJC_METTL3_WT_vs_EV_F01.18228.18228.2 1.14 16-Sep R.TLADIIMEK.L "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1032.5525 0.67 5075 18228 2 1032.552182 517.2835 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.37 3531.1 - 1.16E+06 - - - -0.3399 - 1.477 0.104 - 170.5 1 2 0 -0.0004 9 0 0 0 2.81E+07 4.17E+07 - - - 0.9374 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.18230.18230.2 0.000527 20-Oct K.AVFVLGDAELK.G "sp|Q93074|MED12_HUMAN,tr|Q7Z3Z5|Q7Z3Z5_HUMAN" 2 1160.6441 0.25 5077 18230 2 1160.648881 581.3293 Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens OX=9606 GN=MED12 PE=1 SV=4 4.37 3531.4 - 256775 - - - 4.0977 - 2.13 0.402 - 261 1 2 0 0.0048 11 0 0 0 6.99E+06 2.79E+07 - - - 4.0542 0.9931 230117_WJC_METTL3_WT_vs_EV_F01.18233.18233.2 0.0136 20-Nov R.LDVEEVDLSLR[166.11].L "sp|P57678|GEMI4_HUMAN,tr|I3L2C7|I3L2C7_HUMAN" 2 1296.6801 0.62 5080 18233 2 1296.68714 649.3473 Gem-associated protein 4 OS=Homo sapiens OX=9606 GN=GEMIN4 PE=1 SV=2 3.92 3531.8 - 145556 - - - 5.4547 - 1.544 0.342 - 244.3 1 2 0 0.0071 11 0 0 0 1.53E+06 2.46E+06 - - - 2.7399 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.18240.18240.2 0.0121 14-Sep K.LDYILGLK[136.11].L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 941.5677 0.8 5085 18240 2 941.570846 471.7911 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3532.5 - 3.92E+06 - - - 3.3211 - 1.904 0.303 - 245.2 1 2 0 0.0031 8 0 0 0 4.96E+08 6.17E+08 - - - 3.2201 1 230117_WJC_METTL3_WT_vs_EV_F01.18241.18241.2 9.07E-08 13/22 K.LFVTNDAATILR[166.11].E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1342.7484 7.81 5086 18241 2 1342.752091 672.3815 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3532.6 - 1.70E+06 - - - 2.7332 - 2.627 0.482 - 553 1 2 0 0.0037 12 0 0 0 6.59E+09 8.44E+08 - - - 5.1412 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.18242.18242.2 0.0149 16-Nov R.LSMMLLDSR[166.11].A "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1074.5441 4.02 5087 18242 2 1074.548915 538.2793 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.84 3532.8 - 1.58E+06 - - - 4.4745 - 2.295 0.399 - 458.2 1 2 0 0.0048 9 0 0 0 9.87E+07 2.45E+07 - - - 4.3899 0.9932 230117_WJC_METTL3_WT_vs_EV_F01.18243.18243.2 2.74 14-Jul R.LLILMEAR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 957.5681 1.58 5088 18243 2 957.571062 479.7913 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6 3532.9 - 960626 - - - 3.0692 - 1.518 0.127 - 133.8 1 2 0 0.0029 8 0 0 0 5.70E+07 3.62E+07 - - - 1.2369 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18244.18244.2 0.000243 20-Sep K.AVFVLGDAELK[136.11].G "sp|Q93074|MED12_HUMAN,tr|Q7Z3Z5|Q7Z3Z5_HUMAN" 2 1168.6583 0.21 5089 18244 2 1168.660781 585.3364 Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens OX=9606 GN=MED12 PE=1 SV=4 4.37 3533 - 367661 - - - 2.1016 - 1.814 0.364 - 155.7 1 2 0 0.0025 11 0 0 0 6.99E+06 3.37E+07 - - - 3.3398 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18250.18250.2 0.0216 14-Aug K.LDYILGLK.L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 933.5535 0.8 5094 18250 2 933.554987 467.784 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3533.6 - 1.70E+06 - - - 1.5725 - 1.73 0.312 - 198 1 2 0 0.0015 8 0 0 0 4.98E+08 6.22E+08 - - - 2.9981 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18255.18255.2 0.00351 14-Oct R.VVDLLVIK.G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 897.5899 2.11 5097 18255 2 897.592154 449.8022 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3534.2 - 5.51E+06 - - - 2.5056 - 1.89 0.395 - 282 1 2 0 0.0022 8 0 0 0 1.85E+08 8.76E+07 - - - 3.8777 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.18261.18261.2 0.297 16-Aug R.VVLPYLVPK[136.11].L sp|Q92616|GCN1_HUMAN 1 1034.662 1.18 5101 18261 2 1034.664973 518.3383 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.56 3534.9 - 3.39E+06 - - - 2.9179 - 1.279 0.273 - 177.9 1 2 0 0.003 9 0 0 0 6.21E+07 5.28E+07 - - - 1.7683 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18263.18263.2 0.00417 18-Oct K.LAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1142.627 3.17 5103 18263 2 1142.62964 572.3208 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3535 - 1.95E+06 - - - 2.2798 - 2.097 0.294 - 388.9 1 2 0 0.0026 10 0 0 0 9.29E+08 2.93E+08 - - - 3.2786 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18264.18264.2 0.0822 16-Sep K.VLEALQVLR[166.11].C "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1049.6472 1.33 5104 18264 2 1049.649052 525.8309 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.97 3535.1 - 997014 - - - 1.7168 - 1.993 0.29 - 197.8 1 2 0 0.0018 9 0 0 0 7.06E+07 5.31E+07 - - - 3.1775 0.9889 230117_WJC_METTL3_WT_vs_EV_F01.18265.18265.2 1.08 20-Jul R.QLIPGDEFALR.E "sp|P61371|ISL1_HUMAN,tr|D6RBJ1|D6RBJ1_HUMAN" 2 1257.6717 2.63 5105 18265 2 1257.675876 629.8431 Insulin gene enhancer protein ISL-1 OS=Homo sapiens OX=9606 GN=ISL1 PE=1 SV=1 4.37 3535.3 - 420609 - - - 3.291 - 1.419 0.132 - 156.5 1 2 0 0.0041 11 0 0 0 4.31E+06 1.64E+06 - - - 0.9614 0.9947 230117_WJC_METTL3_WT_vs_EV_F01.18269.18269.2 0.092 16-Aug K.LFLVQLQEK[136.11].A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1124.6685 1.38 5107 18269 2 1124.673388 563.3415 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3535.8 - 1.05E+06 - - - 4.3497 - 1.393 0.3 - 155.2 1 2 0 0.0049 9 0 0 0 6.34E+07 4.61E+07 - - - 2.2142 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18272.18272.2 0.0068 18-Aug K.YLAIAPPIIK.Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1097.6849 1.94 5110 18272 2 1097.686136 549.8497 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3535.9 - 2.19E+06 - - - 1.1552 - 1.636 0.391 - 215.2 1 2 0 0.0013 10 0 0 0 2.21E+08 1.14E+08 - - - 3.3026 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.18281.18281.2 0.179 18-Jul K.LTPEYLQLMK.Y "sp|O94905|ERLN2_HUMAN,tr|E5RHW4|E5RHW4_HUMAN" 2 1234.6631 2.65 5117 18281 2 1234.663287 618.3388 Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1 6 3536.8 - 638854 - - - 0.1142 - 1.718 0.327 - 119.1 1 2 0 0.0001 10 0 0 0 5.09E+07 1.92E+07 - - - 2.9667 0.9946 230117_WJC_METTL3_WT_vs_EV_F01.18282.18282.2 0.114 12-Jun K.FLELLPK[136.11].D "sp|P63010|AP2B1_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 5 866.5357 1.62 5118 18282 2 866.536901 434.2751 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 6 3536.9 - 666548 - - - 1.3964 - 0.976 0.264 - 65.1 1 2 0 0.0012 7 0 0 0 3.95E+07 2.45E+07 - - - 0.9136 0.9623 230117_WJC_METTL3_WT_vs_EV_F01.18283.18283.2 5.07 12-Jul R.SLSDLFR.R "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 836.4392 1.1 5119 18283 2 836.440569 419.2269 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 5.55 3537.1 - 520109 - - - 1.6152 - 1.187 0.002 - 186.3 1 2 0 0.0014 7 0 0 0 3.15E+07 2.85E+07 - - - -0.4015 0.9849 230117_WJC_METTL3_WT_vs_EV_F01.18285.18285.2 0.299 20-Aug K.YGLLPSHASYL.- sp|Q86U90|YRDC_HUMAN 1 1219.6237 - 5121 18285 2 1219.622701 610.8191 "YrdC domain-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=YRDC PE=1 SV=1" 6.74 3537.3 - 457538 - - - -0.8388 - 1.268 0.153 - 106.5 1 2 0 -0.001 11 0 0 0 - - - - - 0.8131 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18288.18288.2 0.0364 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 677.88 5123 18288 2 1006.571949 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3537.7 - 904345 - - - 2.0376 - 1.786 0.341 - 258.5 1 2 0 0.0021 9 0 0 0 8.43E+07 1.24E+05 - - - 3.2369 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.18290.18290.2 4.35E-05 18-Jul K.YLAIAPPIIK[136.11].Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1105.6991 1.94 5125 18290 2 1105.698036 553.8568 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3537.9 - 1.95E+06 - - - -0.9333 - 1.623 0.467 - 155.3 1 2 0 -0.001 10 0 0 0 2.21E+08 1.14E+08 - - - 3.8417 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18291.18291.2 0.00401 14-Oct R.VVDLLVIK[136.11].G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 905.6041 2.11 5126 18291 2 905.60402 453.8093 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3537.9 - 1.71E+06 - - - -0.0939 - 1.706 0.496 - 265.1 1 2 0 -0.0001 8 0 0 0 1.85E+08 8.73E+07 - - - 4.3154 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18292.18292.2 0.0101 16-Aug K.LFLVQLQEK.A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1116.6543 1.17 5127 18292 2 1116.657117 559.3344 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3537.9 - 917737 - - - 2.5263 - 1.796 0.4 - 198.1 1 2 0 0.0028 9 0 0 0 5.15E+07 4.40E+07 - - - 3.6886 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.18297.18297.2 0.00244 16-Aug K.VLEALQVLR.C "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1039.639 1.33 5130 18297 2 1039.638379 520.8268 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.97 3538.6 - 5.46E+06 - - - -0.5781 - 1.948 0.341 - 233.7 1 2 0 -0.0006 9 0 0 0 7.06E+07 5.31E+07 - - - 3.4885 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.18298.18298.2 0.0292 18-Nov K.LAVNMVPFPR[166.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1152.6353 3.17 5131 18298 2 1152.633733 577.3249 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3538.6 - 7.59E+06 - - - -1.3638 - 1.935 0.314 - 529.3 1 2 0 -0.0016 10 0 0 0 9.29E+08 2.93E+08 - - - 3.2023 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18299.18299.2 0.00199 14-Aug R.YQDILVFR.S "sp|P19623|SPEE_HUMAN,tr|K7EKM4|K7EKM4_HUMAN" 2 1052.5655 5.7 5132 18299 2 1052.565447 527.29 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.84 3538.7 - 3.31E+06 - - - -0.0323 - 1.858 0.431 - 206.6 1 2 0 0 8 0 0 0 7.88E+07 1.38E+07 - - - 4.0927 1 230117_WJC_METTL3_WT_vs_EV_F01.18301.18301.2 0.00182 20-Nov K.LIVAYVDDLDR[166.11].R "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1300.6902 1.24 5134 18301 2 1300.693474 651.3524 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 3.93 3539 - 931425 - - - 2.4887 - 2.396 0.478 - 506.5 1 2 0 0.0032 11 0 0 0 1.67E+07 1.35E+07 - - - 4.9343 1 230117_WJC_METTL3_WT_vs_EV_F01.18308.18308.2 1.53E-07 15/30 R.IINEPTAAAIAYGLDK.R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1658.8879 52.06 5139 18308 2 1658.892342 830.4512 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3539.8 - 1.78E+06 - - - 2.6554 - 2.751 0.545 - 412.5 1 2 0 0.0044 16 0 0 0 3.17E+07 6.08E+05 - - - 5.5529 1 230117_WJC_METTL3_WT_vs_EV_F01.18309.18309.2 3.53E-05 20-Dec K.LIVAYVDDLDR.R "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1290.682 1.24 5140 18309 2 1290.685984 646.3483 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 3.93 3540 - 1.05E+06 - - - 3.1123 - 2.322 0.492 - 597.7 1 2 0 0.004 11 0 0 0 1.67E+07 1.35E+07 - - - 4.9526 0.982 230117_WJC_METTL3_WT_vs_EV_F01.18317.18317.2 1.58 12-Jul R.ALLFIPR.R "sp|P08238|HS90B_HUMAN,sp|O00585|CCL21_HUMAN,tr|Q5VZ73|Q5VZ73_HUMAN" 3 828.5222 2.13 5146 18317 2 828.5213 415.2684 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 9.79 3540.9 - 2.42E+06 - - - -1.0368 - 1.4 0.09 - 213.5 1 2 0 -0.0009 7 0 0 0 5.24E+08 2.46E+08 - - - 0.7716 0.9916 230117_WJC_METTL3_WT_vs_EV_F01.18318.18318.2 2.39 12-Sep R.ISFFLEK.E "sp|Q96FF9|CDCA5_HUMAN,tr|B5MBX0|B5MBX0_HUMAN" 2 882.4851 0.7 5147 18318 2 882.484757 442.2498 Sororin OS=Homo sapiens OX=9606 GN=CDCA5 PE=1 SV=1 6 3541 - 1.01E+06 - - - -0.3943 - 1.349 0.143 - 164.2 1 2 0 -0.0003 7 0 0 0 2.24E+07 3.21E+07 - - - 1.0456 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18324.18324.2 0.000456 18-Oct R.VLITTDLLAR.G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 1113.6758 1.57 5151 18324 2 1113.675722 557.8452 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3541.8 - 3.84E+06 - - - -0.0341 - 2.081 0.441 - 312 1 2 0 0 10 0 0 0 2.81E+08 1.80E+08 - - - 4.3438 0.9922 230117_WJC_METTL3_WT_vs_EV_F01.18327.18327.3 0.105 Jul-36 K.LAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1142.627 2.82 5154 18327 3 1142.626827 381.883 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3542.1 - 1.41E+06 - - - -0.182 - 1.598 0.196 - 87.1 2 2 0 -0.0002 10 0 0 0 8.67E+06 3.07E+06 - - - 1.9548 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18332.18332.2 0.00562 18-Oct R.VLITTDLLAR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 1123.684 1.57 5157 18332 2 1123.684877 562.8493 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3542.8 - 1.41E+06 - - - 0.7538 - 2.088 0.396 - 284.4 1 2 0 0.0008 10 0 0 0 2.81E+08 1.80E+08 - - - 4.0206 0.998 230117_WJC_METTL3_WT_vs_EV_F01.18334.18334.2 0.0753 12-Jun R.AVFWDIK.N sp|Q6P2Q9|PRP8_HUMAN 1 877.4698 1.18 5159 18334 2 877.470015 439.7422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3543 - 1.01E+06 - - - 0.2564 - 1.34 0.269 - 161.7 1 2 0 0.0002 7 0 0 0 7.22E+07 6.14E+07 - - - 1.9551 0.9812 230117_WJC_METTL3_WT_vs_EV_F01.18336.18336.2 0.852 12-Jun R.SLSDLFR[166.11].R "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 846.4475 1.13 5161 18336 2 846.448558 424.231 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 5.55 3543.2 - 571680 - - - 1.2641 - 1.34 0.01 - 134.8 1 2 0 0.0011 7 0 0 0 3.13E+07 2.78E+07 - - - 0.0419 0.9949 230117_WJC_METTL3_WT_vs_EV_F01.18339.18339.2 0.00403 16-Sep R.NFFGPEFVK.M sp|Q12923|PTN13_HUMAN 1 1083.5389 0.07 5164 18339 2 1083.536862 542.7767 Tyrosine-protein phosphatase non-receptor type 13 OS=Homo sapiens OX=9606 GN=PTPN13 PE=1 SV=2 6 3543.5 - 625602 - - - -1.9104 - 1.435 0.304 - 132.1 1 2 0 -0.0021 9 0 0 0 6.57E+06 9.88E+07 - - - 2.3306 0.999 230117_WJC_METTL3_WT_vs_EV_F01.18344.18344.2 0.00017 16-Jul K.LLQDFFNGK.E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1080.5604 6.44 5167 18344 2 1080.563889 541.2875 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3544.1 - 1.45E+06 - - - 3.2335 - 1.538 0.41 - 132 1 2 0 0.0035 9 0 0 0 8.03E+07 1.25E+07 - - - 3.3136 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.18351.18351.2 0.181 16-Aug R.LIDFLEC[160.03]GK[136.11].T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1101.562 0.81 5172 18351 2 1101.562485 551.7883 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3544.9 - 7.13E+06 - - - 0.4566 - 1.609 0.335 - 154.2 1 2 0 0.0005 9 0 0 0 1.43E+08 1.77E+08 - - - 2.8911 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18352.18352.2 0.000416 16-Sep K.ATSILEFYR[166.11].E "sp|P09001|RM03_HUMAN,tr|D6RC14|D6RC14_HUMAN,tr|E7ETU7|E7ETU7_HUMAN,tr|H0Y9G6|H0Y9G6_HUMAN,tr|E9PF06|E9PF06_HUMAN" 5 1108.5792 1.01 5173 18352 2 1108.581615 555.2969 "39S ribosomal protein L3, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL3 PE=1 SV=1" 6.05 3545 - 2.95E+06 - - - 2.1514 - 1.705 0.45 - 281.3 1 2 0 0.0024 9 0 0 0 2.67E+07 2.64E+07 - - - 3.9076 1 230117_WJC_METTL3_WT_vs_EV_F01.18354.18354.2 4.40E-06 13/22 R.APVVAIAVLDGR[166.11].G "sp|Q15334|L2GL1_HUMAN,tr|A0A087WW77|A0A087WW77_HUMAN" 2 1189.7058 2.17 5175 18354 2 1189.702257 595.8602 Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens OX=9606 GN=LLGL1 PE=1 SV=3 5.88 3545.3 - 533969 - - - -3.0016 - 2.867 0.519 - 659.4 1 2 0 -0.0036 12 0 0 0 8.69E+06 4.01E+06 - - - 5.6445 1 230117_WJC_METTL3_WT_vs_EV_F01.18363.18363.2 0.000102 22-Dec K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 7.81 5183 18363 2 1332.742612 667.3774 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3546.4 - 3.21E+07 - - - 1.8466 - 2.575 0.506 - 543.3 1 2 0 0.0025 12 0 0 0 6.60E+09 8.45E+08 - - - 5.2662 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18365.18365.2 8.51E-05 16-Sep R.LIDFLEC[160.03]GK.T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1093.5478 0.68 5185 18365 2 1093.549962 547.7812 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3546.5 - 1.50E+07 - - - 1.9935 - 1.713 0.493 - 190.2 1 2 0 0.0022 9 0 0 0 1.50E+08 2.23E+08 - - - 4.2388 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.18366.18366.2 0.226 20-Jun K.LVAASQAALGL.- "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 1012.5917 - 5186 18366 2 1012.593479 507.3031 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.52 3546.6 - 3.59E+06 - - - 1.7608 - 1.245 0.197 - 64.2 1 2 0 0.0018 11 0 0 0 - - - - - 1.0883 0.9594 230117_WJC_METTL3_WT_vs_EV_F01.18367.18367.2 3.29 12-May R.LDFNLIR[166.11].V "sp|P31939|PUR9_HUMAN,tr|C9JLK0|C9JLK0_HUMAN" 2 899.5104 1.52 5187 18367 2 899.510764 450.7625 Bifunctional purine biosynthesis protein ATIC OS=Homo sapiens OX=9606 GN=ATIC PE=1 SV=3 5.84 3546.7 - 2.54E+06 - - - 0.3802 - 1.283 0.025 - 70.1 6 2 0 0.0003 7 0 0 0 1.73E+07 1.14E+07 - - - -0.3325 1 230117_WJC_METTL3_WT_vs_EV_F01.18370.18370.2 2.76E-05 18-Oct K.FYALDPSFPR.M sp|Q08J23|NSUN2_HUMAN 1 1211.5975 1.98 5190 18370 2 1211.600132 606.806 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3547 - 948307 - - - 2.1649 - 2.016 0.561 - 320.9 1 2 0 0.0026 10 0 0 0 1.36E+07 6.84E+06 - - - 5.1407 1 230117_WJC_METTL3_WT_vs_EV_F01.18372.18372.2 4.10E-06 26-Dec K.VLIPSYAAGSIIGK.G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|F8W659|F8W659_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|F8VYI3|F8VYI3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|I3L2B5|I3L2B5_HUMAN" 8 1387.8075 2.42 5192 18372 2 1387.810148 694.911 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.56 3547.2 - 800517 - - - 1.9066 - 2.237 0.524 - 273.2 1 2 0 0.0026 14 0 0 0 8.24E+06 3.41E+06 - - - 4.9309 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18373.18373.2 0.00376 18-Oct K.MLLAISELNK.N sp|Q9H694|BICC1_HUMAN 1 1130.6369 3.71 5193 18373 2 1130.63863 566.3257 Protein bicaudal C homolog 1 OS=Homo sapiens OX=9606 GN=BICC1 PE=1 SV=2 5.75 3547.3 - 729426 - - - 1.5027 - 2.154 0.408 - 244.9 1 2 0 0.0017 10 0 0 0 3.85E+06 1.04E+06 - - - 4.1958 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18374.18374.2 0.00401 20-Oct K.LDPGLIMEQVK[136.11].V sp|Q9Y5L4|TIM13_HUMAN 1 1249.6832 2.53 5194 18374 2 1249.686476 625.8489 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3547.4 - 710761 - - - 2.6535 - 1.93 0.353 - 354.1 1 2 0 0.0033 11 0 0 0 1.86E+07 7.32E+06 - - - 3.426 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.18375.18375.2 0.0176 14-Aug R.VPTIFPLR[166.11].G sp|Q96EK4|THA11_HUMAN 1 951.5781 39.52 5195 18375 2 951.581437 476.7963 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 9.72 3547.6 - 871719 - - - 3.4984 - 1.659 0.354 - 216.2 1 2 0 0.0033 8 0 0 0 6.36E+08 1.61E+07 - - - 3.1813 1 230117_WJC_METTL3_WT_vs_EV_F01.18376.18376.2 5.89E-05 28-Oct R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 20.38 5196 18376 2 1484.911133 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3547.7 - 489036 - - - 2.1873 - 2.219 0.503 - 277.9 1 2 0 0.0032 15 0 0 0 2.50E+06 1.23E+05 - - - 4.7147 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18382.18382.2 0.0194 14/20 K.LALDVEIATYR.K "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1262.6871 958.6 5200 18382 2 1262.690134 632.3508 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 3548.5 - 2.68E+06 - - - 2.44 - 2.782 0.337 - 953.1 1 2 0 0.0031 11 0 0 0 5.09E+08 5.31E+05 - - - 4.297 0.9901 230117_WJC_METTL3_WT_vs_EV_F01.18383.18383.2 0.21 16-Dec K.TLGILGLGR.L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 898.56 2.11 5201 18383 2 898.56448 450.2873 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3548.6 - 1.28E+06 - - - 4.9835 - 1.857 0.161 - 427.5 1 2 0 0.0045 9 0 0 0 6.19E+08 2.94E+08 - - - 2.0194 0.9437 230117_WJC_METTL3_WT_vs_EV_F01.18385.18385.2 0.00304 18-Sep N.MVVDAVLAIK.Y "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1057.6206 11.62 5203 18385 2 1057.623286 529.8176 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.59 3548.7 - 1.41E+06 - - - 2.5841 - 1.687 0.361 - 189.6 1 1 0 0.0027 10 0 0 0 2.45E+07 2.11E+06 - - - 3.1662 0.9973 230117_WJC_METTL3_WT_vs_EV_F01.18387.18387.2 0.159 16-Dec K.TLGILGLGR[166.11].L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 908.5683 2.12 5205 18387 2 908.56981 455.2914 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3548.9 - 1.02E+06 - - - 1.6928 - 1.922 0.074 - 450 1 2 0 0.0015 9 0 0 0 6.18E+08 2.91E+08 - - - 1.4773 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18388.18388.2 0.0428 18-Dec R.ILELDQELIK.A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1212.6966 1.33 5206 18388 2 1212.699052 607.3556 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3549 - 939719 - - - 2.059 - 2.195 0.254 - 365.3 1 2 0 0.0025 10 0 0 0 4.96E+07 3.74E+07 - - - 3.1107 1 230117_WJC_METTL3_WT_vs_EV_F01.18389.18389.2 2.03E-05 13/22 K.IPGIIIAASAVR[166.11].A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1189.7422 2.34 5207 18389 2 1189.745782 595.8784 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3549.2 - 303061 - - - 2.9998 - 2.693 0.417 - 568.9 1 2 0 0.0036 12 0 0 0 1.00E+08 4.29E+07 - - - 4.7264 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.18390.18390.2 0.176 20-Dec R.LGIPDAVSYIK[136.11].K sp|O94874|UFL1_HUMAN 1 1182.674 2.88 5208 18390 2 1182.674967 592.3443 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.83 3549.3 - 460628 - - - 0.8388 - 1.748 0.293 - 276.6 1 2 0 0.001 11 0 0 0 3.47E+07 1.20E+07 - - - 2.7156 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.18391.18391.2 0.0183 14-Aug R.FLFPEGIK[136.11].G "sp|O75891|AL1L1_HUMAN,sp|Q3SY69|AL1L2_HUMAN,tr|C9IZ36|C9IZ36_HUMAN,tr|A0A494C1M4|A0A494C1M4_HUMAN" 4 957.5415 1.06 5209 18391 2 957.540129 479.778 Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L1 PE=1 SV=2 6 3549.4 - 257770 - - - -1.436 - 1.542 0.343 - 139.4 1 2 0 -0.0014 8 0 0 0 2.08E+07 1.97E+07 - - - 2.8801 0.9969 230117_WJC_METTL3_WT_vs_EV_F01.18392.18392.2 0.583 14-Jul R.LTFLNSFK.M "sp|Q9Y487|VPP2_HUMAN,sp|Q93050|VPP1_HUMAN,tr|F5H1T6|F5H1T6_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 5 968.5331 0.9 5210 18392 2 968.536044 485.2738 V-type proton ATPase 116 kDa subunit a2 OS=Homo sapiens OX=9606 GN=ATP6V0A2 PE=1 SV=2 8.75 3549.6 - 218919 - - - 3.0211 - 1.395 0.248 - 92 1 2 0 0.0029 8 0 0 0 3.06E+06 3.39E+06 - - - 1.8758 0.9667 230117_WJC_METTL3_WT_vs_EV_F01.18396.18396.2 4.64 14-Jul R.DVDFELIK.V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 977.507 3.05 5213 18396 2 977.508468 489.7608 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3550 - 817671 - - - 1.5396 - 1.118 0.04 - 122.9 1 2 0 0.0015 8 0 0 0 1.06E+09 3.47E+08 - - - -0.3276 1 230117_WJC_METTL3_WT_vs_EV_F01.18398.18398.2 0.000502 14/22 R.FLAVGLVDNTVR[166.11].L sp|Q15393|SF3B3_HUMAN 1 1312.7379 1.15 5214 18398 2 1312.740948 657.3762 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3550.3 - 7.45E+06 - - - 2.3554 - 2.574 0.526 - 817.2 1 2 0 0.0031 12 0 0 0 1.74E+08 1.52E+08 - - - 5.4127 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.18399.18399.2 0.0254 14-Aug R.IGVMSLIR.K "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 887.5263 1.51 5215 18399 2 887.528247 444.7704 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 3550.3 - 2.98E+06 - - - 2.2399 - 1.527 0.338 - 186.5 1 2 0 0.002 8 0 0 0 4.53E+07 3.00E+07 - - - 2.8135 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18400.18400.2 0.0418 18-Nov R.ILELDQELIK[136.11].A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1220.7108 1.33 5216 18400 2 1220.713315 611.3627 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3550.4 - 2.00E+06 - - - 2.0971 - 2.298 0.226 - 319.2 1 2 0 0.0026 10 0 0 0 4.96E+07 3.73E+07 - - - 3.0319 1 230117_WJC_METTL3_WT_vs_EV_F01.18401.18401.2 0.00316 22-Dec K.IPGIIIAASAVR.A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1179.7339 2.34 5217 18401 2 1179.742195 590.8742 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3550.5 - 1.37E+06 - - - 6.9948 - 2.406 0.441 - 468.3 1 2 0 0.0083 12 0 0 0 1.01E+08 4.30E+07 - - - 4.6057 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.18402.18402.2 0.0846 20-Sep K.LALDMEISAYR.K "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN" 2 1280.6435 1.2 5218 18402 2 1280.649112 641.329 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.37 3550.6 - 628013 - - - 4.4033 - 2.296 0.285 - 352 1 2 0 0.0056 11 0 0 0 1.42E+07 1.19E+07 - - - 3.3927 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.18403.18403.2 0.442 12-Aug K.ILVDLLK.L "sp|Q6P582|MZT2A_HUMAN,sp|Q6NZ67|MZT2B_HUMAN,tr|H7C202|H7C202_HUMAN,tr|B8ZZ87|B8ZZ87_HUMAN,tr|A0A494C0V9|A0A494C0V9_HUMAN,tr|H7BZ50|H7BZ50_HUMAN,tr|H7C173|H7C173_HUMAN" 7 812.5371 2.26 5219 18403 2 812.539631 407.2758 Mitotic-spindle organizing protein 2A OS=Homo sapiens OX=9606 GN=MZT2A PE=1 SV=2 5.84 3550.7 - 611384 - - - 3.0645 - 1.867 0.214 - 170.4 1 2 0 0.0025 7 0 0 0 3.04E+07 1.35E+07 - - - 2.5991 1 230117_WJC_METTL3_WT_vs_EV_F01.18406.18406.2 7.66E-09 24-Dec -.MLSEVLLVSAPGK[136.11].V "sp|Q03426|KIME_HUMAN,tr|F5GXC0|F5GXC0_HUMAN,tr|F5H163|F5H163_HUMAN,tr|F5H092|F5H092_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|F5H368|F5H368_HUMAN,tr|A0A1W2PS16|A0A1W2PS16_HUMAN" 7 1350.7672 80.99 5222 18406 2 1350.769836 676.3909 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 5.75 3551.1 - 341164 - - - 1.9337 - 2.268 0.579 - 386.3 1 2 0 0.0026 13 0 0 0 7.88E+08 9.73E+06 - - - 5.4184 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.18410.18410.2 0.000972 20-Dec K.LDPGLIMEQVK.V sp|Q9Y5L4|TIM13_HUMAN 1 1241.669 2.43 5225 18410 2 1241.673984 621.8418 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3551.8 - 1.29E+06 - - - 4.0462 - 2.013 0.411 - 502.3 1 2 0 0.005 11 0 0 0 1.71E+07 7.05E+06 - - - 3.9677 0.977 230117_WJC_METTL3_WT_vs_EV_F01.18414.18414.2 0.00742 16-Sep R.PLVETIFER[166.11].G "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 1112.6105 1.06 5228 18414 2 1112.612371 557.3125 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.53 3552.1 - 2.73E+06 - - - 1.6547 - 1.915 0.444 - 359.3 1 1 0 0.0018 9 0 0 0 5.97E+07 5.64E+07 - - - 4.1995 0.8937 230117_WJC_METTL3_WT_vs_EV_F01.18416.18416.2 0.201 12-Jul H.ILLWDTR[166.11].N "sp|Q9BTV6|DPH7_HUMAN,sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 3 925.5261 0.54 5230 18416 2 925.528267 463.7703 Diphthine methyltransferase OS=Homo sapiens OX=9606 GN=DPH7 PE=1 SV=2 5.84 3552.2 - 1.12E+06 - - - 2.3716 - 1.41 0.285 - 194.5 1 1 0 0.0022 7 0 0 0 9.45E+06 1.74E+07 - - - 2.234 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18424.18424.2 0.00297 22-Sep R.FLAVGLVDNTVR.L sp|Q15393|SF3B3_HUMAN 1 1302.7296 1.15 5236 18424 2 1302.733093 652.3721 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3553 - 7.14E+06 - - - 2.692 - 1.999 0.413 - 236.9 1 2 0 0.0035 12 0 0 0 1.74E+08 1.52E+08 - - - 3.9128 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18425.18425.3 3.50E-05 Nov-44 R.FLAVGLVDNTVR.L sp|Q15393|SF3B3_HUMAN 1 1302.7296 2.02 5237 18425 3 1302.734185 435.2505 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3553.1 - 402013 - - - 3.5303 - 2.012 0.438 - 143.2 1 2 0 0.0046 12 0 0 0 2.18E+07 1.08E+07 - - - 5.3599 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18426.18426.2 0.000257 22-Dec K.LIVDPALDPALR.R "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN,tr|C9J2Z9|C9J2Z9_HUMAN" 3 1291.75 2.83 5238 18426 2 1291.751757 646.8823 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.21 3553.2 - 778482 - - - 1.3702 - 1.99 0.423 - 394.5 1 2 0 0.0018 12 0 0 0 4.27E+07 1.51E+07 - - - 3.9753 0.9514 230117_WJC_METTL3_WT_vs_EV_F01.18431.18431.2 0.000218 20-Nov R.LLDLVVQPVPR.P sp|Q8WYP5|ELYS_HUMAN 1 1247.7602 1.42 5243 18431 2 1247.764032 624.8874 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.84 3553.8 - 248530 - - - 3.1048 - 2.19 0.374 - 545.9 1 1 0 0.0039 11 0 0 0 1.85E+07 1.31E+07 - - - 3.9228 0.9904 230117_WJC_METTL3_WT_vs_EV_F01.18434.18434.2 0.0286 20-Aug K.NLIDAGVDALR[166.11].V "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1165.6331 1.16 5246 18434 2 1165.62855 583.8238 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.21 3554.1 - 150599 - - - -3.8666 - 1.729 0.338 - 138.5 1 2 0 -0.0045 11 0 0 0 4.39E+06 3.79E+06 - - - 3.0173 1 230117_WJC_METTL3_WT_vs_EV_F01.18435.18435.2 0.00279 28-Dec R.LGALQGDPEALTLYR.E sp|Q9P253|VPS18_HUMAN 1 1615.857 13.47 5247 18435 2 1615.861729 808.9358 Vacuolar protein sorting-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=VPS18 PE=1 SV=2 4.37 3554.3 - 125199 - - - 2.9439 - 2.075 0.523 - 388.6 1 2 0 0.0048 15 0 0 0 2.59E+06 1.92E+05 - - - 4.697 0.9954 230117_WJC_METTL3_WT_vs_EV_F01.18437.18437.2 0.00212 14-Sep K.MLLVDELR.D "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 987.5423 0.96 5248 18437 2 987.540829 494.7784 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 4.37 3554.5 - 1.37E+07 - - - -1.4926 - 1.768 0.191 - 398.2 1 2 0 -0.0015 8 0 0 0 1.54E+08 1.60E+08 - - - 2.1699 0.8849 230117_WJC_METTL3_WT_vs_EV_F01.18440.18440.2 0.0116 16-Jul N.LLLNYGLYR.K "sp|Q92769|HDAC2_HUMAN,sp|Q13547|HDAC1_HUMAN,tr|E5RHE7|E5RHE7_HUMAN,tr|E5RGV4|E5RGV4_HUMAN,tr|H3BM24|H3BM24_HUMAN,tr|E5RJ04|E5RJ04_HUMAN,tr|E5RG37|E5RG37_HUMAN,tr|E5RH52|E5RH52_HUMAN,tr|E5RK19|E5RK19_HUMAN,tr|E5RFP9|E5RFP9_HUMAN,tr|E5RFI6|E5RFI6_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 12 1123.639 1.55 5250 18440 2 1123.643517 562.8268 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 8.59 3554.8 - 1.88E+06 - - - 4.0378 - 1.784 0.359 - 124.5 1 1 0 0.0045 9 0 0 0 1.97E+07 1.27E+07 - - - 3.3658 0.9793 230117_WJC_METTL3_WT_vs_EV_F01.18443.18443.2 0.00421 22-Nov L.PLIPIVVEQTGR.G sp|Q16740|CLPP_HUMAN 1 1320.7765 1.63 5253 18443 2 1320.778907 661.3955 "ATP-dependent Clp protease proteolytic subunit, mitochondrial OS=Homo sapiens OX=9606 GN=CLPP PE=1 SV=1" 6.43 3555.1 - 856898 - - - 1.7952 - 2.464 0.428 - 278.6 1 1 0 0.0024 12 0 0 0 1.29E+07 7.92E+06 - - - 4.5742 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.18444.18444.2 0.00938 18-Oct K.VALLDFGATR.E sp|Q8NI60|COQ8A_HUMAN 1 1061.5869 1.74 5254 18444 2 1061.59154 531.8007 "Atypical kinase COQ8A, mitochondrial OS=Homo sapiens OX=9606 GN=COQ8A PE=1 SV=1" 5.81 3555.2 - 697251 - - - 4.3284 - 1.918 0.374 - 234.5 1 2 0 0.0046 10 0 0 0 8.65E+06 4.96E+06 - - - 3.6199 0.9664 230117_WJC_METTL3_WT_vs_EV_F01.18446.18446.2 0.00324 14/22 H.IISELILTAQER[166.11].D sp|Q96I24|FUBP3_HUMAN 1 1394.8009 1.62 5256 18446 2 1394.804822 698.4077 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3555.5 - 500938 - - - 2.8477 - 2.584 0.398 - 702.2 1 1 0 0.004 12 0 0 0 1.64E+07 1.01E+07 - - - 4.4773 0.8858 230117_WJC_METTL3_WT_vs_EV_F01.18450.18450.2 0.836 20-Jul R.VFEFGGPEVLK[136.11].L "sp|Q08257|QOR_HUMAN,tr|C9JH92|C9JH92_HUMAN,tr|A6NP24|A6NP24_HUMAN" 3 1228.6583 2.82 5260 18450 2 1228.667961 615.3364 Quinone oxidoreductase OS=Homo sapiens OX=9606 GN=CRYZ PE=1 SV=1 4.53 3556 - 336685 - - - 7.8427 - 1.41 0.212 - 95.5 3 2 0 0.0096 11 0 0 0 7.00E+06 2.48E+06 - - - 1.3202 0.9289 230117_WJC_METTL3_WT_vs_EV_F01.18453.18453.2 0.124 18-Oct S.GVAVSDGVIK.V "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PS23|E9PS23_HUMAN" 4 943.5338 2.03 5261 18453 2 943.535694 472.7742 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 5.84 3556.4 - 3.98E+06 - - - 1.9586 - 1.765 0.257 - 219.3 1 1 0 0.0018 10 0 0 0 8.56E+08 4.22E+08 - - - 2.5245 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.18455.18455.2 0.000856 20-Oct R.LGIPDAVSYIK.K sp|O94874|UFL1_HUMAN 1 1174.6598 2.39 5263 18455 2 1174.665084 588.3372 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.83 3556.6 - 1.97E+06 - - - 4.5196 - 2.058 0.402 - 180 1 2 0 0.0053 11 0 0 0 3.37E+07 1.41E+07 - - - 3.961 0.9479 230117_WJC_METTL3_WT_vs_EV_F01.18457.18457.2 27.7 12-Jun K.MIADFLR[166.11].E "sp|Q96R72|OR4K3_HUMAN,sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 4 874.461 1.76 5265 18457 2 874.466062 438.2378 Olfactory receptor 4K3 OS=Homo sapiens OX=9606 GN=OR4K3 PE=3 SV=3 5.59 3556.8 - 884216 - - - 5.7555 - 1.426 0.117 - 111.3 1 2 0 0.005 7 0 0 0 4.62E+07 2.63E+07 - - - 1.028 1 230117_WJC_METTL3_WT_vs_EV_F01.18458.18458.2 0.000344 13/22 H.IISELILTAQER.D sp|Q96I24|FUBP3_HUMAN 1 1384.7926 1.62 5266 18458 2 1384.797722 693.4036 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3557 - 801463 - - - 3.7132 - 2.588 0.471 - 655 1 1 0 0.0051 12 0 0 0 1.66E+07 1.03E+07 - - - 5.0201 0.9917 230117_WJC_METTL3_WT_vs_EV_F01.18473.18473.2 2.02 12-Jul K.MIADFLR.E "sp|Q96R72|OR4K3_HUMAN,sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 4 864.4528 1.69 5278 18473 2 864.456662 433.2337 Olfactory receptor 4K3 OS=Homo sapiens OX=9606 GN=OR4K3 PE=3 SV=3 5.59 3558.7 - 855686 - - - 4.515 - 1.441 0.229 - 230.2 1 2 0 0.0039 7 0 0 0 4.28E+07 2.53E+07 - - - 1.8888 0.999 230117_WJC_METTL3_WT_vs_EV_F01.18478.18478.2 6.16E-05 18-Oct R.YLYTLVITDK[136.11].E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1235.6893 1.46 5283 18478 2 1235.693582 618.8519 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3559.3 - 177667 - - - 3.4726 - 1.958 0.367 - 262.9 1 2 0 0.0043 10 0 0 0 1.25E+09 8.51E+08 - - - 3.6259 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18480.18480.2 0.000631 22-Jul R.LVPVSFEDPEFK.S tr|F5GXE4|F5GXE4_HUMAN 1 1405.7129 5.78 5285 18480 2 1405.717234 703.8637 Arginyl-tRNA--protein transferase 1 OS=Homo sapiens OX=9606 GN=ATE1 PE=1 SV=1 4.14 3559.6 - 53200.1 - - - 3.0597 - 1.566 0.473 - 87.1 1 2 0 0.0043 12 0 0 0 5.16E+06 8.93E+05 - - - 3.7134 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.18483.18483.2 0.00517 14-Sep K.LWGVIDVK.R "sp|Q9UHD1|CHRD1_HUMAN,tr|E9PHZ2|E9PHZ2_HUMAN" 2 928.5382 5.92 5286 18483 2 928.538737 465.2764 Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2 5.84 3560 - 1.37E+06 - - - 0.5751 - 1.628 0.306 - 202.3 1 2 0 0.0005 8 0 0 0 3.77E+07 6.37E+06 - - - 2.7708 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18484.18484.2 0.00021 18-Sep R.YLYTLVITDK.E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1227.6751 1.46 5287 18484 2 1227.678031 614.8448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3560.1 - 1.50E+06 - - - 2.3948 - 1.857 0.323 - 203.8 1 2 0 0.0029 10 0 0 0 1.24E+09 8.50E+08 - - - 3.1535 1 230117_WJC_METTL3_WT_vs_EV_F01.18486.18486.2 1.59E-06 20-Nov K.FGEPVLAGFAR[166.11].S sp|O15067|PUR4_HUMAN 1 1172.6218 4.21 5289 18486 2 1172.62918 587.3182 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 6 3560.4 - 884690 - - - 6.3243 - 2.119 0.496 - 395 1 2 0 0.0074 11 0 0 0 7.35E+07 1.75E+07 - - - 4.7336 0.8733 230117_WJC_METTL3_WT_vs_EV_F01.18487.18487.2 0.385 18-Jun K.LWTMPISSVR[166.11].F "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1198.6408 2.63 5290 18487 2 1198.647262 600.3277 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3560.5 - 351047 - - - 5.4036 - 1.424 0.02 - 94.1 1 2 0 0.0065 10 0 0 0 1.72E+07 6.56E+06 - - - 0.1733 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18493.18493.2 0.00496 16-Aug R.ILFLDPSGK[136.11].V sp|O95881|TXD12_HUMAN 1 996.5735 1.12 5294 18493 2 996.575298 499.294 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3561.3 - 3.41E+06 - - - 1.7711 - 1.645 0.365 - 182.8 1 2 0 0.0018 9 0 0 0 1.17E+09 1.04E+09 - - - 3.1763 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.18494.18494.2 0.000592 20-Dec R.ILDVGFEEELK[136.11].Q "sp|Q9NVP1|DDX18_HUMAN,tr|H7C452|H7C452_HUMAN" 2 1298.6849 1.04 5295 18494 2 1298.690681 650.3497 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 4 3561.4 - 897261 - - - 4.4252 - 2.311 0.434 - 472 1 2 0 0.0057 11 0 0 0 2.77E+07 2.66E+07 - - - 4.5108 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.18496.18496.2 0.433 14-Sep R.LEELQLFK.N "sp|Q96PZ0|PUS7_HUMAN,sp|O95025|SEM3D_HUMAN,sp|O15041|SEM3E_HUMAN,tr|A0A2R8YCX5|A0A2R8YCX5_HUMAN,tr|E7EUH7|E7EUH7_HUMAN" 5 1018.5699 0.66 5297 18496 2 1018.569777 510.2922 Pseudouridylate synthase 7 homolog OS=Homo sapiens OX=9606 GN=PUS7 PE=1 SV=2 4.53 3561.6 - 245545 - - - -0.1188 - 1.708 0.241 - 175.4 1 2 0 -0.0001 8 0 0 0 1.15E+07 1.73E+07 - - - 2.4355 0.995 230117_WJC_METTL3_WT_vs_EV_F01.18499.18499.2 0.631 16-Sep R.FLSGLELVK.Q "sp|Q96S44|PRPK_HUMAN,tr|Q5JZ02|Q5JZ02_HUMAN" 2 1004.5906 1.28 5298 18499 2 1004.59334 503.3026 EKC\KEOPS complex subunit TP53RK OS=Homo sapiens OX=9606 GN=TP53RK PE=1 SV=2 6 3562 - 1.88E+06 - - - 2.6946 - 1.597 0.124 - 172 1 2 0 0.0027 9 0 0 0 5.80E+07 4.54E+07 - - - 1.3103 0.9892 230117_WJC_METTL3_WT_vs_EV_F01.18500.18500.2 0.76 14-May K.DLYSALIK.L sp|O75844|FACE1_HUMAN 1 921.5171 1.04 5299 18500 2 921.516587 461.7658 CAAX prenyl protease 1 homolog OS=Homo sapiens OX=9606 GN=ZMPSTE24 PE=1 SV=2 5.83 3562.1 - 1.31E+06 - - - -0.5936 - 1.157 0.266 - 67.9 13 2 0 -0.0005 8 0 0 0 4.66E+07 4.48E+07 - - - 0.9477 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18507.18507.2 0.000366 16-Oct K.YMAEALLLR.A sp|O94826|TOM70_HUMAN 1 1078.5845 1.7 5304 18507 2 1078.58617 540.2995 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 6 3563 - 627300 - - - 1.5465 - 2.021 0.441 - 263.8 1 2 0 0.0017 9 0 0 0 1.64E+07 9.65E+06 - - - 4.3332 0.9906 230117_WJC_METTL3_WT_vs_EV_F01.18509.18509.2 0.283 14-Jul K.IGGIFAFK.V "sp|P22307|SCP2_HUMAN,tr|H0YF61|H0YF61_HUMAN" 2 851.4905 1.87 5306 18509 2 851.489167 426.7525 Sterol carrier protein 2 OS=Homo sapiens OX=9606 GN=SCP2 PE=1 SV=2 8.75 3563.3 - 387171 - - - -1.5949 - 1.583 0.154 - 93.5 1 2 0 -0.0014 8 0 0 0 1.00E+07 5.36E+06 - - - 1.5633 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18513.18513.2 0.000549 16-Sep K.GIFLGDQWR.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1090.556 2.53 5308 18513 2 1090.556539 546.2853 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3563.8 - 6.75E+06 - - - 0.5135 - 1.6 0.421 - 298 1 2 0 0.0006 9 0 0 0 2.24E+08 8.83E+07 - - - 3.5101 0.9865 230117_WJC_METTL3_WT_vs_EV_F01.18516.18516.2 0.0328 12-Jul K.AFFSPFR.L sp|Q92626|PXDN_HUMAN 1 870.4388 0.82 5311 18516 2 870.438558 436.2267 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 9.79 3564 - 1.12E+06 - - - -0.3056 - 1.344 0.092 - 142.1 1 2 0 -0.0003 7 0 0 0 2.01E+07 2.46E+07 - - - 0.6572 0.9772 230117_WJC_METTL3_WT_vs_EV_F01.18517.18517.2 0.00159 18-Nov R.IPLNPYLNLH.S "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 1192.6604 - 5312 18517 2 1192.662055 597.3375 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.74 3564.1 - 973924 - - - 1.3508 - 2.09 0.414 - 418.9 1 1 0 0.0016 10 0 0 0 - - - - - 4.1559 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18518.18518.2 0.0024 16-Sep K.LEVDIPLVK.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1024.6168 2.24 5313 18518 2 1024.618624 513.3157 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3564.2 - 769909 - - - 1.7333 - 1.796 0.381 - 231.1 1 2 0 0.0018 9 0 0 0 2.27E+08 1.01E+08 - - - 3.5486 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18520.18520.2 0.00124 20-Nov R.ILMLGLDAAGK[136.11].T sp|P62330|ARF6_HUMAN 1 1108.6406 1.28 5315 18520 2 1108.642057 555.3276 ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2 5.84 3564.4 - 419432 - - - 1.344 - 2 0.345 - 238.1 1 2 0 0.0015 11 0 0 0 1.31E+07 1.03E+07 - - - 3.4638 1 230117_WJC_METTL3_WT_vs_EV_F01.18521.18521.2 2.23E-09 14/26 K.FYGPEGPYGVFAGR.D sp|O00264|PGRC1_HUMAN 1 1515.7147 1.52 5316 18521 2 1515.718752 758.8646 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3564.6 - 346835 - - - 2.6971 - 2.49 0.675 - 760.4 1 2 0 0.0041 14 0 0 0 5.87E+07 3.85E+07 - - - 6.3146 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18526.18526.2 0.00309 16-Aug K.GIFLGDQWR[166.11].D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1100.5642 2.51 5319 18526 2 1100.56549 551.2894 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3565.2 - 3.20E+06 - - - 1.1276 - 1.452 0.413 - 207.3 1 2 0 0.0012 9 0 0 0 2.22E+08 8.82E+07 - - - 3.17 0.9788 230117_WJC_METTL3_WT_vs_EV_F01.18527.18527.2 2.4 12-Jul R.SILEYLR.V sp|Q8N1G4|LRC47_HUMAN 1 892.5018 1.48 5320 18527 2 892.500497 447.2582 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 5.72 3565.3 - 1.09E+06 - - - -1.4801 - 1.302 0.133 - 202 1 2 0 -0.0013 7 0 0 0 6.11E+07 4.13E+07 - - - 0.8591 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18529.18529.2 0.0302 12-Aug R.YDLWNLK[136.11].Y sp|Q9ULW3|ABT1_HUMAN 1 958.5004 0.58 5322 18529 2 958.501539 480.2575 Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1 5.83 3565.5 - 464688 - - - 1.2217 - 1.574 0.308 - 191.2 1 2 0 0.0012 7 0 0 0 1.68E+07 2.89E+07 - - - 2.7528 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.18531.18531.2 7.46E-07 22-Dec K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 406.78 5324 18531 2 1382.680135 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3565.8 - 373283 - - - -2.0938 - 2.346 0.419 - 407.3 1 2 0 -0.0029 12 0 0 0 2.49E+07 6.13E+04 - - - 4.3785 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18532.18532.2 3.38E-06 14/26 K.FYGPEGPYGVFAGR[166.11].D sp|O00264|PGRC1_HUMAN 1 1525.7229 1.52 5325 18532 2 1525.725991 763.8687 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3565.9 - 305356 - - - 2.0036 - 1.977 0.518 - 276.1 1 2 0 0.0031 14 0 0 0 5.87E+07 3.85E+07 - - - 4.5764 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18548.18548.2 0.000459 20-Nov R.MLDMGFEPQIR[166.11].R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1345.6398 1.23 5336 18548 2 1345.640328 673.8272 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3567.8 - 797097 - - - 0.3939 - 1.982 0.452 - 497.4 1 2 0 0.0005 11 0 0 0 2.23E+08 1.80E+08 - - - 4.23 0.997 230117_WJC_METTL3_WT_vs_EV_F01.18550.18550.2 0.0115 18-Jun K.FYALDPSFPR[166.11].M sp|Q08J23|NSUN2_HUMAN 1 1221.6058 1.55 5338 18550 2 1221.609588 611.8102 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3568 - 816456 - - - 3.118 - 1.254 0.311 - 116.9 1 2 0 0.0038 10 0 0 0 3.52E+07 2.27E+07 - - - 1.9686 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18551.18551.2 5.21E-05 20-Sep R.MLDMGFEPQIR.R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1335.6315 1.24 5339 18551 2 1335.634905 668.823 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3568.1 - 678376 - - - 2.5284 - 2.043 0.486 - 319.2 1 2 0 0.0034 11 0 0 0 2.23E+08 1.80E+08 - - - 4.5622 0.9912 230117_WJC_METTL3_WT_vs_EV_F01.18556.18556.2 0.22 12-Aug R.SILEYLR[166.11].V sp|Q8N1G4|LRC47_HUMAN 1 902.5101 2 5342 18556 2 902.510297 452.2623 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 5.72 3568.8 - 2.94E+06 - - - 0.2316 - 1.404 0.087 - 244.5 1 2 0 0.0002 7 0 0 0 8.28E+07 4.13E+07 - - - 0.7587 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18557.18557.2 6.03E-06 22-Dec K.GLTPSQIGVILR[166.11].D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1262.7586 0.89 5343 18557 2 1262.759792 632.3866 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3568.9 - 1.15E+06 - - - 0.9503 - 2.33 0.317 - 530.1 1 2 0 0.0012 12 0 0 0 1.03E+08 1.16E+08 - - - 3.6076 0.975 230117_WJC_METTL3_WT_vs_EV_F01.18558.18558.2 0.26 12-Jul R.FQLQLLR[166.11].E sp|Q9P2R3|ANFY1_HUMAN 1 926.5577 1.02 5344 18558 2 926.560523 464.2861 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 9.75 3569.1 - 975120 - - - 3.0392 - 1.487 0.014 - 141.9 2 2 0 0.0028 7 0 0 0 1.73E+07 1.70E+07 - - - 0.2662 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18559.18559.2 1.98E-06 22-Oct K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 0.9 5345 18559 2 1252.751952 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3569.2 - 912867 - - - 1.3011 - 2.031 0.291 - 427.7 1 2 0 0.0016 12 0 0 0 1.04E+08 1.16E+08 - - - 3.0541 0.991 230117_WJC_METTL3_WT_vs_EV_F01.18560.18560.2 0.113 14-Aug K.AFSIDIIR.H "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 933.5284 0.02 5346 18560 2 933.531341 467.7715 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.88 3569.3 - 758137 - - - 3.1858 - 1.618 0.079 - 217.3 1 2 0 0.003 8 0 0 0 1.67E+07 8.60E+08 - - - 1.0748 1 230117_WJC_METTL3_WT_vs_EV_F01.18566.18566.2 3.22E-07 20-Oct K.FGEPVLAGFAR.S sp|O15067|PUR4_HUMAN 1 1162.6135 3.16 5351 18566 2 1162.615931 582.314 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 6 3570.1 - 773301 - - - 2.0961 - 2.298 0.451 - 302.6 1 2 0 0.0024 11 0 0 0 7.55E+07 2.39E+07 - - - 4.6222 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.18568.18568.2 0.507 14-Jul R.EMVLEIIR.E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1001.558 1.42 5352 18568 2 1001.560006 501.7863 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3570.3 - 5.70E+06 - - - 2.0498 - 1.63 0.119 - 224.5 1 2 0 0.0021 8 0 0 0 6.62E+08 4.67E+08 - - - 1.3928 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.18569.18569.2 0.0537 14-Sep K.MAILQIMK[136.11].E "sp|Q13263|TIF1B_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 2 954.5486 1.52 5353 18569 2 954.550863 478.2816 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 8.5 3570.4 - 2.70E+06 - - - 2.3917 - 1.866 0.224 - 348.7 1 2 0 0.0023 8 0 0 0 1.39E+08 9.11E+07 - - - 2.5761 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18570.18570.2 0.0333 14-Sep K.MAILQIMK.E "sp|Q13263|TIF1B_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 2 946.5344 1.52 5354 18570 2 946.535511 474.2745 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 8.5 3570.4 - 3.61E+06 - - - 1.1949 - 1.853 0.312 - 347.3 1 2 0 0.0011 8 0 0 0 1.39E+08 9.11E+07 - - - 3.2053 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.18571.18571.2 0.0536 16-Aug K.ILLITEDLK.N sp|Q08752|PPID_HUMAN 1 1056.6431 3.08 5355 18571 2 1056.644917 529.3288 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 4.37 3570.5 - 1.17E+06 - - - 1.7546 - 1.739 0.191 - 171.1 1 2 0 0.0019 9 0 0 0 4.63E+07 1.50E+07 - - - 2.0519 0.999 230117_WJC_METTL3_WT_vs_EV_F01.18572.18572.2 0.00359 14-Aug R.GFGFVQFK[136.11].N "sp|Q9NW13|RBM28_HUMAN,tr|C9JE21|C9JE21_HUMAN" 2 936.4949 0.79 5356 18572 2 936.495614 469.2547 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 8.75 3570.6 - 1.15E+06 - - - 0.7742 - 1.502 0.303 - 193.1 1 2 0 0.0007 8 0 0 0 2.59E+07 3.28E+07 - - - 2.5056 0.8853 230117_WJC_METTL3_WT_vs_EV_F01.18574.18574.2 2.39 12-Jun R.WMAQYID.- "sp|Q9Y6B6|SAR1B_HUMAN,tr|Q9H029|Q9H029_HUMAN" 2 925.4004 - 5358 18574 2 925.401626 463.7075 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 4.3 3570.8 - 810913 - - - 1.3367 - 0.694 0.131 - 65.9 1 2 0 0.0012 7 0 0 0 - - - - - -1.1492 0.9973 230117_WJC_METTL3_WT_vs_EV_F01.18576.18576.2 0.195 14-Jul K.MMDSLFLK.L sp|O00566|MPP10_HUMAN 1 983.482 1.18 5360 18576 2 983.483995 492.7483 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 5.59 3570.9 - 514810 - - - 2.0173 - 1.242 0.254 - 117.7 1 2 0 0.002 8 0 0 0 9.98E+06 8.44E+06 - - - 1.57 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.18577.18577.2 0.513 12-Jun R.DLFALAR.K sp|Q9Y4W6|AFG32_HUMAN 1 804.4494 1.36 5361 18577 2 804.450449 403.232 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.84 3571.1 - 495820 - - - 1.3189 - 1.206 0.187 - 157.4 1 2 0 0.0011 7 0 0 0 1.99E+07 1.46E+07 - - - 1.0153 1 230117_WJC_METTL3_WT_vs_EV_F01.18585.18585.2 0.000135 16-Nov K.LYMVLITTK.N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 3 1080.6253 1.52 5367 18585 2 1080.627859 541.3199 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 8.59 3572 - 2.52E+06 - - - 2.3644 - 2.031 0.529 - 405.4 1 2 0 0.0026 9 0 0 0 2.46E+07 1.62E+07 - - - 4.9972 0.9914 230117_WJC_METTL3_WT_vs_EV_F01.18586.18586.2 0.0762 14-Jul R.GFGFVQFK.N "sp|Q9NW13|RBM28_HUMAN,tr|C9JE21|C9JE21_HUMAN" 2 928.4807 0.75 5368 18586 2 928.483618 465.2476 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 8.75 3572.1 - 2.05E+06 - - - 3.1546 - 1.279 0.177 - 118.1 1 2 0 0.0029 8 0 0 0 2.61E+07 3.48E+07 - - - 1.0896 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.18587.18587.2 0.104 14-Sep K.VALLLLEK.E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 897.5899 1.3 5369 18587 2 897.591462 449.8022 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3572.2 - 1.87E+06 - - - 1.7346 - 1.767 0.185 - 252.3 1 2 0 0.0016 8 0 0 0 3.20E+07 2.47E+07 - - - 2.1239 0.9806 230117_WJC_METTL3_WT_vs_EV_F01.18588.18588.2 0.554 12-Jul R.FQLQLLR.E sp|Q9P2R3|ANFY1_HUMAN 1 916.5494 1.03 5370 18588 2 916.551629 459.282 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 9.75 3572.3 - 1.47E+06 - - - 2.3916 - 1.384 0.017 - 201.1 1 2 0 0.0022 7 0 0 0 1.75E+07 1.70E+07 - - - 0.1956 0.9944 230117_WJC_METTL3_WT_vs_EV_F01.18590.18590.2 0.000142 16-Sep R.FEELTNLIR[166.11].T "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE4|H3BPE4_HUMAN" 3 1143.6163 0.98 5372 18590 2 1143.620495 572.8154 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.53 3572.5 - 1.09E+06 - - - 3.6297 - 1.587 0.178 - 252.4 1 2 0 0.0042 9 0 0 0 3.75E+07 3.81E+07 - - - 1.6905 1 230117_WJC_METTL3_WT_vs_EV_F01.18591.18591.2 6.83E-08 13/22 K.AFAVGVQQVLLK.V sp|O95373|IPO7_HUMAN 1 1271.7602 1.76 5373 18591 2 1271.764347 636.8874 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 8.8 3572.6 - 811869 - - - 3.2939 - 2.692 0.598 - 550.6 1 2 0 0.0042 12 0 0 0 3.77E+07 2.14E+07 - - - 6.0621 1 230117_WJC_METTL3_WT_vs_EV_F01.18592.18592.2 7.83E-06 22-Dec K.AFAVGVQQVLLK[136.11].V sp|O95373|IPO7_HUMAN 1 1279.7744 1.76 5374 18592 2 1279.77751 640.8945 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 8.8 3572.8 - 634649 - - - 2.4629 - 2.446 0.537 - 520.8 1 2 0 0.0032 12 0 0 0 3.77E+07 2.14E+07 - - - 5.3598 0.9935 230117_WJC_METTL3_WT_vs_EV_F01.18593.18593.2 0.0392 18-Sep K.ALQEFDLALR.G "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1174.6346 0.66 5375 18593 2 1174.641319 588.3246 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 4.37 3572.9 - 483744 - - - 5.7005 - 1.807 0.317 - 218.6 1 2 0 0.0067 10 0 0 0 1.47E+07 2.22E+07 - - - 3.0318 0.9941 230117_WJC_METTL3_WT_vs_EV_F01.18594.18594.2 0.0949 16-Jun K.YMLPLDNLK.V "sp|Q9UQ16|DYN3_HUMAN,sp|P50570|DYN2_HUMAN,tr|E5RHK8|E5RHK8_HUMAN" 3 1105.5842 10.97 5376 18594 2 1105.583532 553.7994 Dynamin-3 OS=Homo sapiens OX=9606 GN=DNM3 PE=1 SV=4 5.83 3573 - 462724 - - - -0.5744 - 1.268 0.228 - 61.1 1 2 0 -0.0006 9 0 0 0 4.47E+06 4.08E+05 - - - 1.4117 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.18599.18599.2 0.115 14-Aug R.EMVLEIIR[166.11].E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1011.5662 1.42 5380 18599 2 1011.568234 506.7904 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3573.6 - 1.19E+07 - - - 1.988 - 1.764 0.259 - 420.2 1 2 0 0.002 8 0 0 0 6.63E+08 4.67E+08 - - - 2.6651 0.9941 230117_WJC_METTL3_WT_vs_EV_F01.18601.18601.2 0.0999 12-Jun R.EIFITFR.V sp|Q96EY1|DNJA3_HUMAN 1 924.5069 1.82 5381 18601 2 924.50824 463.2607 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.1 3573.9 - 2.73E+06 - - - 1.4462 - 1.174 0.194 - 120 2 2 0 0.0013 7 0 0 0 4.79E+07 2.63E+07 - - - 0.8473 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.18603.18603.2 0.0478 16-Aug R.LLYGMALVR[166.11].F "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3R6|A0A7I2V3R6_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V4V0|A0A7I2V4V0_HUMAN,tr|A0A7I2V5R7|A0A7I2V5R7_HUMAN,tr|A0A7I2V653|A0A7I2V653_HUMAN,tr|A0A7I2YQI7|A0A7I2YQI7_HUMAN" 7 1044.6029 1.3 5383 18603 2 1044.604572 523.3087 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 8.75 3574.1 - 1.04E+06 - - - 1.5604 - 1.58 0.193 - 130.5 1 2 0 0.0016 9 0 0 0 2.35E+07 1.81E+07 - - - 1.7893 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.18606.18606.2 0.0479 16-Sep R.SLIAEVLVK.L sp|O95969|SG1D2_HUMAN 1 970.6063 122.59 5386 18606 2 970.608439 486.3104 Secretoglobin family 1D member 2 OS=Homo sapiens OX=9606 GN=SCGB1D2 PE=2 SV=1 5.72 3574.5 - 767693 - - - 2.2213 - 1.664 0.259 - 178.5 1 2 0 0.0022 9 0 0 0 4.36E+07 3.56E+05 - - - 2.4265 0.9958 230117_WJC_METTL3_WT_vs_EV_F01.18613.18613.2 0.0489 16-Sep R.ILFLDPSGK.V sp|O95881|TXD12_HUMAN 1 988.5593 1.12 5391 18613 2 988.564903 495.2869 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3575.3 - 2.45E+07 - - - 5.6345 - 1.709 0.406 - 215.4 1 2 0 0.0056 9 0 0 0 1.17E+09 1.04E+09 - - - 3.5884 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18614.18614.4 6.39E-07 23/120 R.KHAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2325.1812 1.63 5392 18614 4 2325.191067 582.3026 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3575.4 - 1.18E+06 - - - 4.2354 - 3.905 0.478 - 285.7 1 2 0 0.0098 21 0 0 0 7.19E+06 4.40E+06 - - - 3.8342 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18618.18618.2 0.00013 16-Nov R.LYSVSYLLK[136.11].D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1092.631 0.75 5394 18618 2 1092.631546 547.3228 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.5 3576 - 2.10E+06 - - - 0.4558 - 2.088 0.337 - 311.7 1 2 0 0.0005 9 0 0 0 6.08E+07 8.05E+07 - - - 3.6598 0.999 230117_WJC_METTL3_WT_vs_EV_F01.18619.18619.2 0.00967 16-Sep R.LLYGMALVR.F "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3R6|A0A7I2V3R6_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V4V0|A0A7I2V4V0_HUMAN,tr|A0A7I2V5R7|A0A7I2V5R7_HUMAN,tr|A0A7I2V653|A0A7I2V653_HUMAN,tr|A0A7I2YQI7|A0A7I2YQI7_HUMAN" 7 1034.5947 1.28 5395 18619 2 1034.596849 518.3046 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 8.75 3576.1 - 903532 - - - 2.1032 - 1.596 0.291 - 202.9 1 2 0 0.0022 9 0 0 0 2.32E+07 1.81E+07 - - - 2.5421 1 230117_WJC_METTL3_WT_vs_EV_F01.18620.18620.2 1.59E-05 22-Dec R.MGLAISLVATEK[136.11].E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 1239.6988 1.39 5396 18620 2 1239.699115 620.8567 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.75 3576.1 - 1.74E+06 - - - 0.246 - 2.528 0.502 - 398.9 1 2 0 0.0003 12 0 0 0 5.91E+07 4.24E+07 - - - 5.1889 1 230117_WJC_METTL3_WT_vs_EV_F01.18624.18624.2 0.000619 14/22 R.MGLAISLVATEK.E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 1231.6846 1.39 5398 18624 2 1231.689636 616.8496 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.75 3576.6 - 1.53E+06 - - - 4.0806 - 2.814 0.529 - 760.6 1 2 0 0.005 12 0 0 0 5.92E+07 4.24E+07 - - - 5.6688 0.981 230117_WJC_METTL3_WT_vs_EV_F01.18628.18628.2 0.227 12-Jun R.DLFALAR[166.11].K sp|Q9Y4W6|AFG32_HUMAN 1 814.4577 1.36 5402 18628 2 814.460439 408.2361 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.84 3577.1 - 558371 - - - 3.4145 - 1.116 0.167 - 161.7 1 2 0 0.0028 7 0 0 0 1.99E+07 1.46E+07 - - - 0.6213 1 230117_WJC_METTL3_WT_vs_EV_F01.18632.18632.2 1.09E-06 18-Nov K.FYALDPSFPR.M sp|Q08J23|NSUN2_HUMAN 1 1211.5975 1.69 5405 18632 2 1211.599424 606.806 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3577.6 - 900894 - - - 1.5806 - 2.034 0.608 - 402.4 1 2 0 0.0019 10 0 0 0 2.00E+07 1.19E+07 - - - 5.5129 0.9707 230117_WJC_METTL3_WT_vs_EV_F01.18636.18636.2 0.798 14-Jun K.SIGDIFLK[136.11].Y "sp|Q9H8V3|ECT2_HUMAN,tr|H7C3G1|H7C3G1_HUMAN" 2 899.5208 1.19 5408 18636 2 899.523984 450.7677 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 5.55 3578 - 1.23E+06 - - - 3.5741 - 1.046 0.164 - 82.2 1 2 0 0.0032 8 0 0 0 2.35E+07 1.98E+07 - - - 0.3869 0.9926 230117_WJC_METTL3_WT_vs_EV_F01.18637.18637.2 0.135 14-Jul R.NILIDFTK.K "sp|P19367|HXK1_HUMAN,sp|P52789|HXK2_HUMAN,tr|E9PB90|E9PB90_HUMAN" 3 962.5437 1.34 5409 18637 2 962.547085 482.2791 Hexokinase-1 OS=Homo sapiens OX=9606 GN=HK1 PE=1 SV=3 5.84 3578.1 - 789452 - - - 3.5344 - 1.399 0.183 - 121.2 1 2 0 0.0034 8 0 0 0 1.18E+07 8.82E+06 - - - 1.4042 0.9867 230117_WJC_METTL3_WT_vs_EV_F01.18640.18640.2 9.31 12-Jul K.EVILPIK.V sp|Q4G0P3|HYDIN_HUMAN 1 810.5215 1.44 5412 18640 2 810.52375 406.268 Hydrocephalus-inducing protein homolog OS=Homo sapiens OX=9606 GN=HYDIN PE=1 SV=3 6.1 3578.5 - 581512 - - - 2.7871 - 1.557 0.022 - 212.2 1 2 0 0.0023 7 0 0 0 2.66E+07 1.85E+07 - - - 0.6057 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.18642.18642.2 0.313 14-Aug K.GPFLLGIK.A sp|P21399|ACOHC_HUMAN 1 843.5218 4.32 5414 18642 2 843.5234 422.7682 Cytoplasmic aconitate hydratase OS=Homo sapiens OX=9606 GN=ACO1 PE=1 SV=3 8.75 3578.7 - 480906 - - - 1.8672 - 1.581 0.092 - 173.5 1 2 0 0.0016 8 0 0 0 3.75E+06 8.69E+05 - - - 1.1015 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.18645.18645.2 3.85E-05 20-Aug K.LVNIYDSMPLR.Y sp|Q9UBQ6|EXTL2_HUMAN 1 1319.6908 0.64 5417 18645 2 1319.696871 660.8527 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 5.84 3579.1 - 425172 - - - 4.6321 - 2.123 0.441 - 225 1 2 0 0.0061 11 0 0 0 3.49E+06 5.46E+06 - - - 4.3329 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.18650.18650.2 0.0786 18-Nov K.ALQEFDLALR[166.11].G "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1184.6429 0.68 5421 18650 2 1184.645587 593.3287 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 4.37 3579.7 - 603898 - - - 2.2741 - 1.924 0.26 - 385.2 1 2 0 0.0027 10 0 0 0 1.47E+07 2.17E+07 - - - 2.7872 0.999 230117_WJC_METTL3_WT_vs_EV_F01.18653.18653.2 0.00301 16-Sep R.ELGELIPLR[166.11].Q "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1048.6156 1.2 5423 18653 2 1048.619416 525.3151 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.53 3580 - 1.71E+06 - - - 3.6238 - 1.738 0.42 - 338.9 1 2 0 0.0038 9 0 0 0 2.20E+07 1.84E+07 - - - 3.741 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18661.18661.2 1.38E-05 24-Oct K.LFPDTPLALDANK[136.11].K sp|Q12906|ILF3_HUMAN 1 1421.7646 0.74 5431 18661 2 1421.768192 711.8896 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3580.8 - 361028 - - - 2.5398 - 1.976 0.503 - 282.5 1 2 0 0.0036 13 0 0 0 1.46E+07 1.98E+07 - - - 4.503 0.9111 230117_WJC_METTL3_WT_vs_EV_F01.18667.18667.2 0.00615 14/20 F.IGAIAIGDLVK[136.11].S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1076.6685 6.28 5435 18667 2 1076.672372 539.3415 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 3581.7 - 5.98E+06 - - - 3.6 - 2.244 0.288 - 428.3 1 1 0 0.0039 11 0 0 0 2.56E+08 4.08E+07 - - - 3.3535 1 230117_WJC_METTL3_WT_vs_EV_F01.18671.18671.2 0.00148 18-Oct R.VLLMELEEAR[166.11].G sp|P12270|TPR_HUMAN 1 1211.6459 1.46 5439 18671 2 1211.65083 606.8302 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3582 - 1.19E+06 - - - 4.0441 - 2.211 0.464 - 430.1 1 2 0 0.0049 10 0 0 0 4.25E+07 2.90E+07 - - - 4.6813 0.9908 230117_WJC_METTL3_WT_vs_EV_F01.18672.18672.2 0.00732 14-Aug R.LYLLQGIR.N "sp|Q9Y5A7|NUB1_HUMAN,tr|H3BM74|H3BM74_HUMAN,tr|H3BM14|H3BM14_HUMAN" 3 974.5913 1.78 5440 18672 2 974.597647 488.3029 NEDD8 ultimate buster 1 OS=Homo sapiens OX=9606 GN=NUB1 PE=1 SV=2 8.75 3582.2 - 1.03E+06 - - - 6.5104 - 1.744 0.348 - 180.1 1 2 0 0.0063 8 0 0 0 1.12E+07 6.28E+06 - - - 3.2868 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.18676.18676.2 7.95E-06 24-Nov K.LFPDTPLALDANK.K sp|Q12906|ILF3_HUMAN 1 1413.7504 0.74 5444 18676 2 1413.756931 707.8825 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3582.7 - 550858 - - - 4.6331 - 1.876 0.468 - 368.9 1 2 0 0.0066 13 0 0 0 1.46E+07 1.98E+07 - - - 4.1103 1 230117_WJC_METTL3_WT_vs_EV_F01.18677.18677.2 0.00035 18-Dec K.TLVQILTEPR.N sp|O76031|CLPX_HUMAN 1 1168.6816 2.24 5445 18677 2 1168.687698 585.3481 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3582.8 - 507449 - - - 5.2409 - 2.206 0.462 - 617.7 1 2 0 0.0061 10 0 0 0 2.57E+07 1.15E+07 - - - 4.6598 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18679.18679.2 0.0722 16-Nov K.LALFQAIGK.E "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 959.5804 1.55 5447 18679 2 959.582696 480.7975 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 8.75 3583.1 - 361354 - - - 2.3896 - 2.103 0.307 - 260.3 1 2 0 0.0023 9 0 0 0 6.39E+06 4.14E+06 - - - 3.4584 0.939 230117_WJC_METTL3_WT_vs_EV_F01.18682.18682.2 1.32 20-Jun K.VEVSEDEPASK.A sp|O75683|SURF6_HUMAN 1 1188.551 0.94 5450 18682 2 1188.551561 595.2828 Surfeit locus protein 6 OS=Homo sapiens OX=9606 GN=SURF6 PE=1 SV=3 4 3583.5 - 324170 - - - 0.4611 - 1.006 0.062 - 46.7 2 2 0 0.0005 11 0 0 0 7.50E+06 7.95E+06 - - - -0.6195 0.9919 230117_WJC_METTL3_WT_vs_EV_F01.18690.18690.2 0.268 18-Jun K.FLALYLHGAA.- "sp|Q9BZE1|RM37_HUMAN,tr|A6NHR2|A6NHR2_HUMAN" 2 1074.5862 - 5457 18690 2 1074.58938 538.3004 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 6.74 3584.4 - 2.12E+06 - - - 2.9444 - 1.114 0.23 - 81.8 1 2 0 0.0032 10 0 0 0 - - - - - 1.0401 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18691.18691.2 0.00505 12-Sep K.C[160.03]ALDFFR.Q sp|P51970|NDUA8_HUMAN 1 927.4273 1.5 5458 18691 2 927.429094 464.7209 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3584.4 - 1.13E+06 - - - 1.9635 - 1.79 0.362 - 382.7 1 2 0 0.0018 7 0 0 0 3.05E+07 2.04E+07 - - - 3.5589 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.18692.18692.2 0.0679 12-Sep K.C[160.03]ALDFFR[166.11].Q sp|P51970|NDUA8_HUMAN 1 937.4355 1.49 5459 18692 2 937.437437 469.725 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3584.5 - 913488 - - - 2.0204 - 1.559 0.305 - 430.8 1 2 0 0.0019 7 0 0 0 3.04E+07 2.03E+07 - - - 2.7001 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18693.18693.2 0.0153 16-Oct K.LQDPFSLYR.C sp|P21912|SDHB_HUMAN 1 1137.5819 3.75 5460 18693 2 1137.584017 569.7982 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.84 3584.6 - 713038 - - - 1.897 - 2.108 0.249 - 293.6 1 2 0 0.0022 9 0 0 0 5.64E+07 1.51E+07 - - - 3.0369 0.9844 230117_WJC_METTL3_WT_vs_EV_F01.18694.18694.2 0.441 12-Jul R.NYLSIFR.K sp|P07384|CAN1_HUMAN 1 911.4865 16.46 5461 18694 2 911.485773 456.7505 Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1 8.75 3584.7 - 635912 - - - -0.7998 - 1.166 0.168 - 168.1 1 2 0 -0.0007 7 0 0 0 2.07E+07 1.26E+06 - - - 0.7682 1 230117_WJC_METTL3_WT_vs_EV_F01.18696.18696.2 6.45E-07 22/28 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 1.44 5463 18696 2 1458.761332 730.386 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3584.9 - 414016 - - - 2.6564 - 3.971 0.612 - 1858.4 1 2 0 0.0039 15 0 0 0 1.92E+08 1.34E+08 - - - 6.9504 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18697.18697.2 2.26E-05 18-Oct K.LGMNLMNELK.Q "sp|Q16890|TPD53_HUMAN,tr|E9PNK6|E9PNK6_HUMAN,tr|E9PNQ9|E9PNQ9_HUMAN,tr|E9PPQ1|E9PPQ1_HUMAN,tr|J3KNE7|J3KNE7_HUMAN" 5 1161.5886 2.69 5464 18697 2 1161.590991 581.8016 Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1 6 3585 - 412172 - - - 2.0575 - 2.224 0.428 - 249.9 1 2 0 0.0024 10 0 0 0 8.95E+06 3.33E+06 - - - 4.4326 0.9459 230117_WJC_METTL3_WT_vs_EV_F01.18700.18700.2 2.17 12-May K.SMLNFLK.K "sp|Q7Z6Z7|HUWE1_HUMAN,tr|A0A087X1S3|A0A087X1S3_HUMAN" 2 851.4575 4.82 5467 18700 2 851.459884 426.736 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 8.47 3585.3 - 232609 - - - 2.7882 - 1.04 0.066 - 53.3 1 2 0 0.0024 7 0 0 0 6.27E+06 1.30E+06 - - - -0.348 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.18708.18708.2 0.0202 18-Sep R.LGLLGLPAPK[136.11].N sp|Q99459|CDC5L_HUMAN 1 985.6416 1.16 5473 18708 2 985.643072 493.8281 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3586.2 - 7.28E+06 - - - 1.5411 - 1.888 0.091 - 152.2 1 2 0 0.0015 10 0 0 0 1.28E+08 1.10E+08 - - - 1.4866 1 230117_WJC_METTL3_WT_vs_EV_F01.18709.18709.2 4.16E-06 16/28 R.LPAAGVGDMVMATVK[136.11].K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1466.7717 1.44 5474 18709 2 1466.773365 734.3931 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3586.3 - 5.65E+06 - - - 1.1645 - 3.332 0.534 - 861.7 1 2 0 0.0017 15 0 0 0 1.92E+08 1.34E+08 - - - 5.9436 1 230117_WJC_METTL3_WT_vs_EV_F01.18710.18710.3 1.05E-07 15/56 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 1.53 5475 18710 3 1458.759082 487.2598 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3586.4 - 4.01E+06 - - - 1.114 - 2.841 0.49 - 389.5 1 2 0 0.0016 15 0 0 0 6.85E+07 4.46E+07 - - - 6.7272 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18711.18711.2 0.3 14-Jul R.LLLEEIYR[166.11].G "sp|Q9Y2P8|RCL1_HUMAN,tr|Q5VZU2|Q5VZU2_HUMAN,tr|Q5VZU3|Q5VZU3_HUMAN" 3 1057.6047 0.74 5476 18711 2 1057.607334 529.8096 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 4.53 3586.4 - 3.64E+06 - - - 2.4745 - 1.657 0.373 - 172.1 1 2 0 0.0026 8 0 0 0 2.28E+07 3.08E+07 - - - 3.3182 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18712.18712.2 0.003 13/22 K.YILAATLDNTLK[136.11].L sp|P61964|WDR5_HUMAN 1 1342.7588 1.37 5477 18712 2 1342.760764 672.3867 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 5.83 3586.5 - 3.38E+06 - - - 1.4865 - 2.285 0.414 - 391.7 1 2 0 0.002 12 0 0 0 3.91E+07 2.85E+07 - - - 4.2725 1 230117_WJC_METTL3_WT_vs_EV_F01.18713.18713.2 0.109 13/20 K.PLVVQVPTFAR.R sp|O00257|CBX4_HUMAN 1 1225.7183 2.97 5478 18713 2 1225.720544 613.8664 E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3 10.18 3586.7 - 1.15E+06 - - - 1.8365 - 2.296 0.491 - 628.1 1 1 0 0.0023 11 0 0 0 5.11E+06 1.72E+06 - - - 4.9153 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18717.18717.2 0.00152 20-Sep K.LFVINEVC[160.03]EMK[136.11].N sp|Q8TDN6|BRX1_HUMAN 1 1388.6923 -1 5482 18717 2 1388.693296 695.3534 Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2 4.53 3587.1 - 433518 - - - 0.6848 - 1.903 0.358 - 262.4 1 2 0 0.001 11 0 0 0 0.00E+00 0.00E+00 - - - 3.4255 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18722.18722.2 0.00674 14-Jul R.LLLEEIYR.G "sp|Q9Y2P8|RCL1_HUMAN,tr|Q5VZU2|Q5VZU2_HUMAN,tr|Q5VZU3|Q5VZU3_HUMAN" 3 1047.5964 0.74 5485 18722 2 1047.598765 524.8055 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 4.53 3587.7 - 3.11E+06 - - - 2.2127 - 1.725 0.325 - 185.8 1 2 0 0.0023 8 0 0 0 2.28E+07 3.08E+07 - - - 3.0851 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18723.18723.2 0.00151 20-Nov K.LGLENAEALIR[166.11].L sp|P10155|RO60_HUMAN 1 1207.68 2.42 5486 18723 2 1207.683522 604.8473 60 kDa SS-A\Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2 4.53 3587.7 - 3.07E+06 - - - 2.9105 - 2.107 0.379 - 307.8 1 2 0 0.0035 11 0 0 0 3.89E+07 1.61E+07 - - - 3.8553 1 230117_WJC_METTL3_WT_vs_EV_F01.18724.18724.2 4.39E-08 17/30 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 19.63 5487 18724 2 1686.897204 844.4543 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3587.8 - 2.92E+06 - - - 1.849 - 3.26 0.588 - 840.5 1 2 0 0.0031 16 0 0 0 8.64E+07 4.40E+06 - - - 6.2883 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.18726.18726.2 0.117 12-Jul R.TIFSYFK.G sp|Q9UJV9|DDX41_HUMAN 1 904.4695 1.21 5489 18726 2 904.469288 453.242 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 8.26 3587.9 - 2.57E+06 - - - -0.1846 - 1.266 0.199 - 159.6 1 2 0 -0.0002 7 0 0 0 4.89E+07 4.04E+07 - - - 1.2581 1 230117_WJC_METTL3_WT_vs_EV_F01.18728.18728.2 0.000116 20-Dec R.LYEAYLPETFR.R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1400.6976 2.34 5491 18728 2 1400.701 701.3561 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3588 - 1.66E+06 - - - 2.4152 - 2.484 0.498 - 527.6 1 2 0 0.0034 11 0 0 0 6.48E+07 2.77E+07 - - - 5.1796 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18732.18732.2 0.0185 18-Oct K.TLVQILTEPR[166.11].N sp|O76031|CLPX_HUMAN 1 1178.6898 2.24 5495 18732 2 1178.691876 590.3522 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3588.4 - 896330 - - - 1.7248 - 2.093 0.432 - 405.1 1 2 0 0.002 10 0 0 0 2.57E+07 1.15E+07 - - - 4.2928 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18737.18737.2 0.00399 14-Aug K.IGELFALR.H "sp|Q9NWS8|RMND1_HUMAN,tr|A0A804HHW6|A0A804HHW6_HUMAN,tr|A0A087WXU0|A0A087WXU0_HUMAN,tr|A0A2R8Y4J4|A0A2R8Y4J4_HUMAN,tr|A0A804HKF8|A0A804HKF8_HUMAN,tr|A0A804HLE1|A0A804HLE1_HUMAN" 6 917.5335 0.28 5500 18737 2 917.53376 459.774 Required for meiotic nuclear division protein 1 homolog OS=Homo sapiens OX=9606 GN=RMND1 PE=1 SV=2 6 3588.8 - 767639 - - - 0.3357 - 1.456 0.395 - 177.2 1 2 0 0.0003 8 0 0 0 3.77E+06 1.36E+07 - - - 3.0914 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18740.18740.2 0.00541 16-Oct K.LLQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1118.5748 13.53 5502 18740 2 1118.577423 560.2947 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3589.2 - 1.03E+06 - - - 2.3333 - 2.109 0.399 - 340.5 1 2 0 0.0026 9 0 0 0 5.42E+08 4.01E+07 - - - 4.146 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18742.18742.2 0.00272 20-Oct R.LYEAYLPETFR[166.11].R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1410.7059 2.36 5503 18742 2 1410.710841 706.3602 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3589.4 - 3.19E+06 - - - 3.5117 - 2.073 0.436 - 209.6 1 2 0 0.005 11 0 0 0 6.54E+07 2.77E+07 - - - 4.2318 1 230117_WJC_METTL3_WT_vs_EV_F01.18744.18744.2 2.91E-08 22-Dec K.FGEAIGMGFPVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1259.6464 0.94 5505 18744 2 1259.648474 630.8305 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3589.5 - 1.73E+06 - - - 1.6624 - 2.548 0.541 - 487.5 1 2 0 0.0021 12 0 0 0 1.52E+08 1.62E+08 - - - 5.4971 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18745.18745.2 0.00542 22-Oct K.GGIVGMTLPIAR.D "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 1183.6747 1.45 5506 18745 2 1183.676726 592.8446 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 9.75 3589.6 - 1.26E+06 - - - 1.6998 - 1.748 0.394 - 247.7 1 2 0 0.002 12 0 0 0 2.16E+07 1.49E+07 - - - 3.4199 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.18746.18746.2 0.00737 12-Jul R.VWSDFLR.V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 921.4709 2.31 5507 18746 2 921.472093 461.7427 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.81 3589.7 - 1.08E+06 - - - 1.3468 - 1.478 0.263 - 243 1 2 0 0.0012 7 0 0 0 1.97E+07 8.52E+06 - - - 2.2211 1 230117_WJC_METTL3_WT_vs_EV_F01.18748.18748.2 5.27E-07 15/30 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 18.37 5509 18748 2 1696.904404 849.4585 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3590 - 541970 - - - 1.2075 - 3.046 0.556 - 635.9 1 2 0 0.002 16 0 0 0 8.09E+07 4.40E+06 - - - 5.8854 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.18749.18749.2 1.32 12-Jul K.IAFIAWK[136.11].S "sp|Q5UIP0|RIF1_HUMAN,tr|H7BZN3|H7BZN3_HUMAN" 2 855.5098 1.22 5510 18749 2 855.51077 428.7622 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 8.75 3590.1 - 426981 - - - 1.1221 - 1.432 0.168 - 122.5 1 2 0 0.001 7 0 0 0 3.85E+06 3.15E+06 - - - 1.4193 0.9843 230117_WJC_METTL3_WT_vs_EV_F01.18752.18752.2 0.13 12-Jul R.AVIFITK.R "sp|P47992|XCL1_HUMAN,sp|Q9UBD3|XCL2_HUMAN" 2 790.4953 10.32 5513 18752 2 790.497575 396.2549 Lymphotactin OS=Homo sapiens OX=9606 GN=XCL1 PE=1 SV=1 8.8 3590.5 - 264052 - - - 2.9083 - 1.6 0.001 - 156.1 1 2 0 0.0023 7 0 0 0 3.67E+06 3.56E+05 - - - 0.5369 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18755.18755.2 0.00438 20-Dec K.LGLENAEALIR.L sp|P10155|RO60_HUMAN 1 1197.6717 2.42 5515 18755 2 1197.672355 599.8431 60 kDa SS-A\Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2 4.53 3590.9 - 1.01E+06 - - - 0.516 - 2.037 0.357 - 302.7 1 2 0 0.0006 11 0 0 0 3.89E+07 1.61E+07 - - - 3.6023 1 230117_WJC_METTL3_WT_vs_EV_F01.18759.18759.3 1.43E-12 20/60 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 18.64 5518 18759 3 1686.898794 563.3053 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3591.2 - 5.67E+06 - - - 2.7915 - 3.877 0.629 - 600 1 2 0 0.0047 16 0 0 0 6.21E+07 3.33E+06 - - - 9.0283 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18763.18763.2 0.0142 14-Aug R.WVVPVLPK.G "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 936.5797 1.77 5522 18763 2 936.581435 469.2971 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3591.4 - 1.69E+06 - - - 1.8802 - 1.579 0.406 - 261.6 1 2 0 0.0018 8 0 0 0 1.32E+07 7.45E+06 - - - 3.4168 1 230117_WJC_METTL3_WT_vs_EV_F01.18764.18764.2 0.000166 18-Nov R.EDIVVPVYLR.E "sp|P51784|UBP11_HUMAN,tr|G5E9A6|G5E9A6_HUMAN" 2 1201.6707 5.83 5523 18764 2 1201.675268 601.8426 Ubiquitin carboxyl-terminal hydrolase 11 OS=Homo sapiens OX=9606 GN=USP11 PE=1 SV=3 4.37 3591.5 - 1.54E+06 - - - 3.823 - 2.41 0.509 - 512.3 1 2 0 0.0046 10 0 0 0 2.60E+07 4.46E+06 - - - 5.2543 0.996 230117_WJC_METTL3_WT_vs_EV_F01.18765.18765.2 0.197 14-Jun R.WVVPVLPK[136.11].G "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 944.5939 1.77 5524 18765 2 944.596013 473.3042 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3591.6 - 1.22E+06 - - - 2.2645 - 1.191 0.236 - 108.7 1 2 0 0.0021 8 0 0 0 1.32E+07 7.45E+06 - - - 1.3106 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18766.18766.2 0.00138 18-Dec K.TNVALMC[160.03]MLR.E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1207.5876 1.28 5525 18766 2 1207.590857 604.8011 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 7.91 3591.6 - 1.16E+06 - - - 2.7344 - 2.242 0.432 - 599.9 1 2 0 0.0033 10 0 0 0 8.73E+06 6.84E+06 - - - 4.4843 1 230117_WJC_METTL3_WT_vs_EV_F01.18768.18768.2 0.000173 13/18 K.TNVALMC[160.03]MLR[166.11].E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1217.5958 1.28 5527 18768 2 1217.599133 609.8052 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 7.91 3591.8 - 662451 - - - 2.7168 - 2.629 0.481 - 717.9 1 2 0 0.0033 10 0 0 0 8.73E+06 6.84E+06 - - - 5.2907 0.9888 230117_WJC_METTL3_WT_vs_EV_F01.18775.18775.2 0.42 12-Aug R.LQFLFAK.D "sp|Q7Z3K3|POGZ_HUMAN,tr|H0YCT3|H0YCT3_HUMAN" 2 865.5062 1.05 5534 18775 2 865.509088 433.7604 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 8.75 3592.7 - 280352 - - - 3.3657 - 1.279 0.159 - 174.4 1 2 0 0.0029 7 0 0 0 8.12E+06 7.75E+06 - - - 0.9942 0.999 230117_WJC_METTL3_WT_vs_EV_F01.18778.18778.2 0.0178 16-Aug R.ILFLDPSGK[136.11].V sp|O95881|TXD12_HUMAN 1 996.5735 0.98 5536 18778 2 996.576252 499.294 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3593 - 771090 - - - 2.7283 - 1.615 0.336 - 142.3 1 2 0 0.0027 9 0 0 0 2.47E+07 2.53E+07 - - - 2.9086 1 230117_WJC_METTL3_WT_vs_EV_F01.18780.18780.2 6.31E-07 22-Dec K.FGEAIGMGFPVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1251.6322 0.94 5538 18780 2 1251.634603 626.8234 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3593.1 - 5.38E+06 - - - 1.9359 - 2.335 0.534 - 436.2 1 2 0 0.0024 12 0 0 0 1.52E+08 1.62E+08 - - - 5.2156 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18781.18781.2 0.841 14-Aug K.MDELQLFR[166.11].G "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0T971|A0A7P0T971_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7P0Z4D1|A0A7P0Z4D1_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0T946|A0A7P0T946_HUMAN,tr|A0A7P0TBK7|A0A7P0TBK7_HUMAN" 14 1060.5251 1.02 5539 18781 2 1060.527458 531.2698 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.37 3593.1 - 3.68E+06 - - - 2.2366 - 1.984 0.27 - 302.9 1 2 0 0.0024 8 0 0 0 1.93E+07 1.89E+07 - - - 3.1008 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18782.18782.2 0.000546 14-Sep K.MDELQLFR.G "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0T971|A0A7P0T971_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7P0Z4D1|A0A7P0Z4D1_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0T946|A0A7P0T946_HUMAN,tr|A0A7P0TBK7|A0A7P0TBK7_HUMAN" 14 1050.5168 1.09 5540 18782 2 1050.51898 526.2657 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.37 3593.1 - 3.65E+06 - - - 2.0599 - 2.092 0.228 - 501.5 1 2 0 0.0022 8 0 0 0 2.08E+07 1.90E+07 - - - 2.9505 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.18783.18783.2 0.00424 14-Sep K.YLELLGYR[166.11].K "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 7 1035.5629 1.64 5541 18783 2 1035.565448 518.7887 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6 3593.2 - 2.43E+06 - - - 2.5068 - 1.932 0.187 - 284.7 1 2 0 0.0026 8 0 0 0 1.56E+07 9.48E+06 - - - 2.4075 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18784.18784.2 0.0152 14-Sep R.EALAFIIR[166.11].S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 941.5574 1.01 5542 18784 2 941.559335 471.786 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3593.2 - 2.33E+06 - - - 2.0848 - 1.827 0.311 - 331 1 2 0 0.002 8 0 0 0 3.15E+07 3.13E+07 - - - 3.1551 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18787.18787.2 0.0222 14-Aug R.EALAFIIR.S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 931.5491 1.02 5545 18787 2 931.550516 466.7818 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3593.4 - 1.85E+06 - - - 1.5179 - 1.795 0.295 - 264.7 1 2 0 0.0014 8 0 0 0 3.19E+07 3.13E+07 - - - 2.9838 1 230117_WJC_METTL3_WT_vs_EV_F01.18788.18788.2 1.11E-07 13/22 R.LLYMAIDGVAPR.A sp|Q9H0D6|XRN2_HUMAN 1 1317.7115 1.08 5546 18788 2 1317.714115 659.863 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3593.5 - 1.84E+06 - - - 1.9898 - 2.555 0.51 - 783.1 1 2 0 0.0026 12 0 0 0 6.66E+07 6.15E+07 - - - 5.2752 0.999 230117_WJC_METTL3_WT_vs_EV_F01.18789.18789.2 0.0398 20-Nov K.NPLIINSIIDK.A "sp|Q9UNQ2|DIM1_HUMAN,tr|A0A494C0G7|A0A494C0G7_HUMAN,tr|B4DRY2|B4DRY2_HUMAN,tr|A0A7P0T8X7|A0A7P0T8X7_HUMAN,tr|A0A0C4DGB1|A0A0C4DGB1_HUMAN,tr|A0A7P0T967|A0A7P0T967_HUMAN,tr|A0A7P0T9J1|A0A7P0T9J1_HUMAN,tr|A0A7P0Z4I0|A0A7P0Z4I0_HUMAN,tr|A0A7P0T9Y7|A0A7P0T9Y7_HUMAN,tr|D6RCL3|D6RCL3_HUMAN" 10 1238.7234 0.84 5547 18789 2 1238.726666 620.369 Probable dimethyladenosine transferase OS=Homo sapiens OX=9606 GN=DIMT1 PE=1 SV=1 5.84 3593.5 - 1.71E+06 - - - 2.6059 - 2.076 0.25 - 359.1 1 2 0 0.0032 11 0 0 0 1.21E+07 1.44E+07 - - - 2.8625 1 230117_WJC_METTL3_WT_vs_EV_F01.18790.18790.2 6.62E-06 22-Dec R.LLYMAIDGVAPR[166.11].A sp|Q9H0D6|XRN2_HUMAN 1 1327.7198 1.08 5548 18790 2 1327.728743 664.8672 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3593.6 - 1.53E+06 - - - 6.7635 - 2.311 0.574 - 596.3 1 2 0 0.009 12 0 0 0 6.65E+07 6.13E+07 - - - 5.4818 0.9859 230117_WJC_METTL3_WT_vs_EV_F01.18794.18794.2 0.039 20-Jun R.VLPSITTEILK.S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1212.7329 1.46 5552 18794 2 1212.730511 607.3737 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 3593.9 - 694671 - - - -2.0029 - 1.062 0.303 - 77.1 1 2 0 -0.0024 11 0 0 0 5.35E+08 3.66E+08 - - - 1.4409 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.18797.18797.2 0.0102 14-Jul K.YLELLGYR.K "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 7 1025.5546 1.66 5554 18797 2 1025.557084 513.7846 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6 3594.3 - 2.64E+06 - - - 2.4397 - 1.495 0.374 - 181.6 1 2 0 0.0025 8 0 0 0 1.57E+07 9.48E+06 - - - 3.0154 0.969 230117_WJC_METTL3_WT_vs_EV_F01.18799.18799.2 0.00703 18-Aug R.VLGLGLGC[160.03]LR.L "sp|Q9BRJ7|TIRR_HUMAN,tr|W4VSQ8|W4VSQ8_HUMAN,tr|K7EIN2|K7EIN2_HUMAN,tr|K7ENA3|K7ENA3_HUMAN" 4 1056.6114 3.97 5556 18799 2 1056.620088 529.313 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3594.4 - 3.03E+06 - - - 8.2367 - 1.663 0.318 - 167.4 1 2 0 0.0087 10 0 0 0 2.43E+07 6.11E+06 - - - 2.8067 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.18800.18800.2 0.00312 22-Oct K.GGIVGMTLPIAR[166.11].D "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 1193.683 1.41 5557 18800 2 1193.689116 597.8488 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 9.75 3594.4 - 3.00E+06 - - - 5.137 - 2.124 0.335 - 273.3 1 2 0 0.0061 12 0 0 0 2.09E+07 1.49E+07 - - - 3.4954 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.18805.18805.2 0.0099 12-Jul R.LQFLFAK[136.11].D "sp|Q7Z3K3|POGZ_HUMAN,tr|H0YCT3|H0YCT3_HUMAN" 2 873.5204 1.01 5562 18805 2 873.524824 437.7675 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 8.75 3595 - 870860 - - - 5.0932 - 1.734 0.329 - 139.6 1 2 0 0.0044 7 0 0 0 8.25E+06 8.17E+06 - - - 3.2137 1 230117_WJC_METTL3_WT_vs_EV_F01.18807.18807.2 5.06E-05 22-Oct R.VIQEGLEGLVLK.D sp|P49916|DNLI3_HUMAN 1 1296.7653 2.42 5564 18807 2 1296.771455 649.3899 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 4.53 3595.3 - 486770 - - - 4.7441 - 2.132 0.501 - 265.5 1 2 0 0.0062 12 0 0 0 2.84E+06 1.18E+06 - - - 4.7314 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18808.18808.2 0.000125 20-Nov R.VYPQAVYFPIR.T "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1351.7289 2.27 5565 18808 2 1351.733177 676.8717 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.56 3595.4 - 465758 - - - 3.1952 - 2.154 0.429 - 549.9 1 2 0 0.0043 11 0 0 0 3.98E+06 1.76E+06 - - - 4.284 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18818.18818.2 0.311 20-Oct K.LVFLGLDNAGK.T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1145.6445 1.56 5573 18818 2 1145.647864 573.8295 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3596.7 - 1.79E+07 - - - 2.9721 - 2.025 0.353 - 268 1 2 0 0.0034 11 0 0 0 4.89E+08 3.14E+08 - - - 3.5559 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18819.18819.2 0.0507 16-Oct K.VNIIPIIAK.A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 979.643 1.08 5574 18819 2 979.645131 490.8288 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3596.8 - 5.65E+06 - - - 2.1722 - 2.07 0.333 - 391.2 1 2 0 0.0021 9 0 0 0 3.84E+07 3.55E+07 - - - 3.6047 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.18820.18820.2 3.99E-05 16-Aug R.LVLDWDSVR.A "sp|Q68EM7|RHG17_HUMAN,tr|C9IZD3|C9IZD3_HUMAN,tr|I3L4P6|I3L4P6_HUMAN" 3 1101.5819 2.11 5575 18820 2 1101.585738 551.7982 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4.21 3596.8 - 4.01E+06 - - - 3.5213 - 1.755 0.427 - 229.3 1 2 0 0.0039 9 0 0 0 4.58E+07 2.17E+07 - - - 3.8209 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18821.18821.2 0.0467 16-Aug K.WPGDILAYK.E sp|Q9UG63|ABCF2_HUMAN 1 1061.5546 1.39 5576 18821 2 1061.556448 531.7846 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 5.83 3596.9 - 2.27E+06 - - - 1.7578 - 1.921 0.296 - 213.7 1 2 0 0.0019 9 0 0 0 1.85E+07 1.33E+07 - - - 3.1154 0.9969 230117_WJC_METTL3_WT_vs_EV_F01.18823.18823.2 0.13 12-Aug R.NITLWLK[136.11].Y "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 894.5418 0.78 5578 18823 2 894.543922 448.2782 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 8.75 3597.1 - 1.50E+06 - - - 2.3286 - 1.303 0.225 - 206.1 1 2 0 0.0021 7 0 0 0 8.74E+06 1.12E+07 - - - 1.5408 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18824.18824.2 8.21E-05 20-Dec R.VLPSITTEILK[136.11].S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1220.7471 1.46 5579 18824 2 1220.7499 611.3808 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 3597.2 - 1.39E+06 - - - 2.2609 - 1.992 0.414 - 492.5 1 2 0 0.0028 11 0 0 0 5.35E+08 3.66E+08 - - - 3.9622 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.18826.18826.2 0.562 16-Aug R.ALLLSTYIK.F "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|A0A0G2JS82|A0A0G2JS82_HUMAN,tr|A0A0G2JQM1|A0A0G2JQM1_HUMAN" 4 1020.6219 1.23 5581 18826 2 1020.621053 511.3182 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 8.63 3597.5 - 954888 - - - -0.8622 - 1.747 0.179 - 155.8 1 2 0 -0.0009 9 0 0 0 1.25E+07 1.02E+07 - - - 1.9769 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18827.18827.3 0.00108 Dec-44 R.LLYMAIDGVAPR.A sp|Q9H0D6|XRN2_HUMAN 1 1317.7115 0.69 5582 18827 3 1317.713185 440.2444 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3597.6 - 813372 - - - 1.284 - 1.974 0.326 - 215.8 1 2 0 0.0017 12 0 0 0 3.55E+06 5.14E+06 - - - 4.0591 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.18830.18830.2 0.000528 20-Aug R.FYSLLDPSYAK.N sp|P46977|STT3A_HUMAN 1 1302.6496 2.17 5585 18830 2 1302.655829 652.3321 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 5.83 3598 - 382528 - - - 4.7787 - 1.48 0.408 - 136.6 1 2 0 0.0062 11 0 0 0 4.71E+06 2.18E+06 - - - 3.1131 0.9823 230117_WJC_METTL3_WT_vs_EV_F01.18831.18831.2 7.2 12-Jun K.ELLALLK[136.11].C "sp|Q92560|BAP1_HUMAN,sp|Q8NA66|CNBD1_HUMAN,sp|Q8NGS7|O13C8_HUMAN,sp|Q8NGV5|O13D1_HUMAN,sp|Q8NGS4|O13F1_HUMAN,tr|A0A087WTB2|A0A087WTB2_HUMAN,tr|F8W6N3|F8W6N3_HUMAN,tr|H0Y8E8|H0Y8E8_HUMAN,tr|H0YC59|H0YC59_HUMAN,tr|A0A286YF94|A0A286YF94_HUMAN" 10 806.5357 1.5 5586 18831 2 806.538466 404.2751 Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Homo sapiens OX=9606 GN=BAP1 PE=1 SV=2 6.1 3598.1 - 276970 - - - 3.4406 - 1.366 0.089 - 108.7 1 2 0 0.0028 7 0 0 0 2.36E+06 1.57E+06 - - - 0.6857 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.18835.18835.2 0.0587 20-Oct K.NPLIINSIIDK[136.11].A "sp|Q9UNQ2|DIM1_HUMAN,tr|A0A494C0G7|A0A494C0G7_HUMAN,tr|B4DRY2|B4DRY2_HUMAN,tr|A0A7P0T8X7|A0A7P0T8X7_HUMAN,tr|A0A0C4DGB1|A0A0C4DGB1_HUMAN,tr|A0A7P0T967|A0A7P0T967_HUMAN,tr|A0A7P0T9J1|A0A7P0T9J1_HUMAN,tr|A0A7P0Z4I0|A0A7P0Z4I0_HUMAN,tr|A0A7P0T9Y7|A0A7P0T9Y7_HUMAN,tr|D6RCL3|D6RCL3_HUMAN" 10 1246.7376 0.97 5589 18835 2 1246.74284 624.3761 Probable dimethyladenosine transferase OS=Homo sapiens OX=9606 GN=DIMT1 PE=1 SV=1 5.84 3598.6 - 377731 - - - 4.1725 - 1.767 0.245 - 260.6 1 2 0 0.0052 11 0 0 0 8.65E+06 8.89E+06 - - - 2.389 0.999 230117_WJC_METTL3_WT_vs_EV_F01.18837.18837.2 0.000473 16-Sep R.MADFWLTEK.D sp|Q9NRX2|RM17_HUMAN 1 1139.5321 1.29 5590 18837 2 1139.53657 570.7733 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 4.37 3598.8 - 957024 - - - 3.8946 - 1.864 0.442 - 207.1 1 2 0 0.0044 9 0 0 0 1.58E+07 1.22E+07 - - - 4.1058 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18838.18838.2 0.0373 16-Sep K.SLLAWQSLR.R "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1072.6029 1.19 5591 18838 2 1072.605945 537.3087 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 9.47 3598.9 - 472135 - - - 2.8119 - 2.064 0.33 - 303 1 2 0 0.003 9 0 0 0 9.85E+06 8.31E+06 - - - 3.5739 0.9954 230117_WJC_METTL3_WT_vs_EV_F01.18840.18840.2 1.35 16-Jul R.ALLLSTYIK[136.11].F "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|A0A0G2JS82|A0A0G2JS82_HUMAN,tr|A0A0G2JQM1|A0A0G2JQM1_HUMAN" 4 1028.6361 1.23 5593 18840 2 1028.637027 515.3253 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 8.63 3599 - 565337 - - - 0.8691 - 1.479 0.123 - 129.8 1 2 0 0.0009 9 0 0 0 1.25E+07 1.02E+07 - - - 1.0814 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.18841.18841.2 0.0334 14-Jun R.QAFYFALR.D "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1014.5287 1.06 5594 18841 2 1014.532626 508.2716 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.75 3599.1 - 409519 - - - 3.8688 - 1.364 0.286 - 87.7 1 2 0 0.0039 8 0 0 0 1.05E+07 9.93E+06 - - - 2.0884 0.9933 230117_WJC_METTL3_WT_vs_EV_F01.18842.18842.2 0.331 12-Jun R.LWLAALK.D sp|Q9P2D3|HTR5B_HUMAN 1 813.5113 2.83 5595 18842 2 813.512905 407.7629 HEAT repeat-containing protein 5B OS=Homo sapiens OX=9606 GN=HEATR5B PE=1 SV=2 8.75 3599.2 - 57041.1 - - - 2.0221 - 1.289 0.134 - 86.9 1 2 0 0.0016 7 0 0 0 1.92E+06 6.76E+05 - - - 0.8346 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.18848.18848.2 0.033 16-Sep R.GDLLFLTNR.V "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 1047.5713 1.11 5599 18848 2 1047.574286 524.7929 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.84 3600 - 1.40E+06 - - - 2.8552 - 1.483 0.246 - 207.9 1 2 0 0.003 9 0 0 0 1.46E+07 1.32E+07 - - - 1.9971 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.18850.18850.2 0.000862 14-Jul R.ELSPLFLR.F sp|O75691|UTP20_HUMAN 1 973.5597 1.02 5601 18850 2 973.562766 487.7871 Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3 6.1 3600.3 - 787809 - - - 3.1832 - 1.462 0.361 - 179.5 1 2 0 0.0031 8 0 0 0 1.17E+07 1.15E+07 - - - 2.8518 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.18851.18851.2 0.0616 16-Sep R.VLAINILGR.F sp|O43747|AP1G1_HUMAN 1 967.6179 0.41 5602 18851 2 967.620841 484.8162 AP-1 complex subunit gamma-1 OS=Homo sapiens OX=9606 GN=AP1G1 PE=1 SV=5 9.72 3600.4 - 695061 - - - 3.0901 - 1.896 0.3 - 248.9 1 2 0 0.003 9 0 0 0 7.83E+06 1.90E+07 - - - 3.1067 0.9288 230117_WJC_METTL3_WT_vs_EV_F01.18852.18852.2 5.71 12-Jun R.NAFDLFK[136.11].L "sp|Q99549|MPP8_HUMAN,tr|A0A0A0MT47|A0A0A0MT47_HUMAN" 2 861.4476 0.93 5603 18852 2 861.451069 431.7311 M-phase phosphoprotein 8 OS=Homo sapiens OX=9606 GN=MPHOSPH8 PE=1 SV=2 5.84 3600.5 - 681095 - - - 4.0223 - 1.213 0.043 - 113.4 1 2 0 0.0035 7 0 0 0 5.26E+06 5.62E+06 - - - -0.0307 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18857.18857.2 0.00163 13/26 K.YILVTGGVISGIGK.G "sp|P17812|PYRG1_HUMAN,sp|Q9NRF8|PYRG2_HUMAN,tr|A0A3B3ITH9|A0A3B3ITH9_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 7 1375.8075 2.2 5608 18857 2 1375.811553 688.911 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 8.59 3601.2 - 305297 - - - 2.9445 - 2.369 0.436 - 457.6 1 2 0 0.0041 14 0 0 0 6.48E+06 2.94E+06 - - - 4.4243 0.998 230117_WJC_METTL3_WT_vs_EV_F01.18860.18860.2 0.000181 26-Nov K.YILVTGGVISGIGK[136.11].G "sp|P17812|PYRG1_HUMAN,sp|Q9NRF8|PYRG2_HUMAN,tr|A0A3B3ITH9|A0A3B3ITH9_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 7 1383.8217 2.2 5611 18860 2 1383.82869 692.9181 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 8.59 3601.6 - 183046 - - - 5.0498 - 1.802 0.518 - 246 1 2 0 0.007 14 0 0 0 6.48E+06 2.94E+06 - - - 4.3426 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.18865.18865.2 0.0156 14-Jul R.ILFFNTPK.K "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 978.5539 1.31 5614 18865 2 978.55659 490.2842 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 8.75 3602.1 - 5.03E+06 - - - 2.796 - 1.57 0.372 - 128.6 1 2 0 0.0027 8 0 0 0 1.06E+08 8.11E+07 - - - 3.1482 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.18866.18866.2 0.0371 14-Jul R.ILFFNTPK[136.11].K "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 986.5681 1.4 5615 18866 2 986.570106 494.2913 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 8.75 3602.1 - 3.15E+06 - - - 2.0799 - 1.508 0.325 - 113.9 1 2 0 0.0021 8 0 0 0 1.16E+08 8.30E+07 - - - 2.6797 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.18867.18867.2 0.0538 12-Jul K.LIFYDLR.G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 938.5226 1.19 5616 18867 2 938.524439 470.2686 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3602.1 - 3.05E+06 - - - 2.0095 - 1.463 0.339 - 195.5 1 2 0 0.0019 7 0 0 0 7.69E+07 6.47E+07 - - - 2.7499 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18868.18868.2 5.62E-05 18-Aug K.ELLTSFGPLK[136.11].A "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1111.6369 1.66 5617 18868 2 1111.639147 556.8257 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6.1 3602.2 - 2.60E+06 - - - 2.0564 - 1.816 0.454 - 202.2 1 2 0 0.0023 10 0 0 0 8.67E+07 5.23E+07 - - - 4.0589 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18869.18869.2 0.043 16-Oct R.FEALNLSFK.N "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 12 1067.5651 1.58 5618 18869 2 1067.56752 534.7898 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 6 3602.3 - 1.03E+06 - - - 2.2228 - 1.905 0.317 - 276.3 1 2 0 0.0024 9 0 0 0 1.29E+08 8.17E+07 - - - 3.2461 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18870.18870.2 0.0003 14-Aug R.QAFYFALR[166.11].D "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1024.537 1.06 5619 18870 2 1024.537493 513.2758 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.75 3602.3 - 994441 - - - 0.5095 - 1.634 0.364 - 252.3 1 2 0 0.0005 8 0 0 0 1.05E+07 9.93E+06 - - - 3.2103 0.9807 230117_WJC_METTL3_WT_vs_EV_F01.18872.18872.2 0.237 12-Jul R.FPFEIVK.M "sp|Q9UQ16|DYN3_HUMAN,sp|Q05193|DYN1_HUMAN,sp|P50570|DYN2_HUMAN,tr|A0A0D9SFB1|A0A0D9SFB1_HUMAN,tr|A0A1B0GU67|A0A1B0GU67_HUMAN,tr|A0A0D9SFE4|A0A0D9SFE4_HUMAN,tr|H7C5U0|H7C5U0_HUMAN,tr|E5RIK2|E5RIK2_HUMAN,tr|K7EMQ3|K7EMQ3_HUMAN,tr|A0A0U1RQP1|A0A0U1RQP1_HUMAN,tr|E5RHK8|E5RHK8_HUMAN" 11 878.4902 0.77 5621 18872 2 878.494013 440.2524 Dynamin-3 OS=Homo sapiens OX=9606 GN=DNM3 PE=1 SV=4 6 3602.5 - 442653 - - - 4.3506 - 1.297 0.183 - 143.8 2 2 0 0.0038 7 0 0 0 8.91E+06 1.16E+07 - - - 1.081 1 230117_WJC_METTL3_WT_vs_EV_F01.18877.18877.2 5.29E-06 15/26 R.ALMGSPQLVAAVVR.T "sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9J826|C9J826_HUMAN" 5 1410.8017 999 5626 18877 2 1410.805624 706.4081 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 9.79 3603.1 - 351415 - - - 2.7779 - 2.799 0.49 - 695.3 1 2 0 0.0039 14 0 0 0 1.53E+07 0.00E+00 - - - 5.2418 0.9911 230117_WJC_METTL3_WT_vs_EV_F01.18881.18881.2 0.237 18-Jul K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.21 5628 18881 2 1086.647619 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3603.6 - 460226 - - - 3.578 - 1.481 0.155 - 120.4 1 2 0 0.0039 10 0 0 0 5.75E+08 4.75E+08 - - - 1.2808 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.18884.18884.2 0.00424 20-Jul K.YLLDSC[160.03]APLLR[166.11].Y sp|Q92616|GCN1_HUMAN 1 1329.699 1.15 5631 18884 2 1329.699521 665.8568 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.83 3603.9 - 375517 - - - 0.3708 - 1.569 0.33 - 149.5 1 2 0 0.0005 11 0 0 0 1.35E+07 1.17E+07 - - - 2.6968 0.9284 230117_WJC_METTL3_WT_vs_EV_F01.18885.18885.2 2.54 12-Jul R.NLPFLIK[136.11].K sp|Q86TB9|PATL1_HUMAN 1 851.536 1.22 5632 18885 2 851.537314 426.7753 Protein PAT1 homolog 1 OS=Homo sapiens OX=9606 GN=PATL1 PE=1 SV=2 8.75 3604 - 311761 - - - 1.5137 - 0.988 0.023 - 152.4 1 2 0 0.0013 7 0 0 0 2.04E+07 1.68E+07 - - - -0.8278 0.9913 230117_WJC_METTL3_WT_vs_EV_F01.18886.18886.2 2.2 16-Aug K.ALLSALELK[136.11].K sp|P49454|CENPF_HUMAN 1 964.6048 1.44 5633 18886 2 964.605964 483.3097 Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3 6.05 3604.1 - 253502 - - - 1.1725 - 1.518 0.08 - 117.7 4 2 0 0.0011 9 0 0 0 7.01E+06 4.86E+06 - - - 0.5701 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.18888.18888.2 0.0335 16-Oct K.ALLSALELK.K sp|P49454|CENPF_HUMAN 1 956.5906 1.31 5635 18888 2 956.590536 479.3026 Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3 6.05 3604.3 - 246932 - - - -0.1014 - 1.896 0.2 - 227.1 1 2 0 -0.0001 9 0 0 0 6.35E+06 4.86E+06 - - - 2.369 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18891.18891.2 0.00712 13/24 R.LIEETISIAMATK[136.11].E "sp|O95249|GOSR1_HUMAN,tr|E9PCW1|E9PCW1_HUMAN,tr|G5E9T8|G5E9T8_HUMAN" 3 1426.7833 0.75 5638 18891 2 1426.786705 714.3989 Golgi SNAP receptor complex member 1 OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 4.53 3604.7 - 100911 - - - 2.4089 - 2.305 0.419 - 394.4 1 2 0 0.0034 13 0 0 0 5.92E+06 7.92E+06 - - - 4.2779 0.999 230117_WJC_METTL3_WT_vs_EV_F01.18896.18896.2 0.331 14-Aug R.FLIQNVLR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1011.6105 1.46 5641 18896 2 1011.611462 506.8125 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.75 3605.3 - 2.14E+06 - - - 0.9796 - 1.565 0.269 - 270.4 1 2 0 0.001 8 0 0 0 2.19E+08 1.50E+08 - - - 2.3783 0.999 230117_WJC_METTL3_WT_vs_EV_F01.18897.18897.2 0.00772 12-Jun R.EFIEMWR[166.11].L "sp|Q7L0Y3|TM10C_HUMAN,tr|C9JVB6|C9JVB6_HUMAN" 2 1019.4774 0.73 5642 18897 2 1019.479812 510.746 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 4.53 3605.4 - 850543 - - - 2.3581 - 1.478 0.329 - 140.8 1 2 0 0.0024 7 0 0 0 1.00E+07 1.37E+07 - - - 2.7082 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.18904.18904.2 0.0166 14-Jul R.FLIQNVLR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1001.6022 1.46 5647 18904 2 1001.60396 501.8084 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.75 3606.3 - 1.10E+07 - - - 1.7562 - 1.33 0.313 - 164.5 1 2 0 0.0018 8 0 0 0 2.19E+08 1.50E+08 - - - 2.2124 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18907.18907.2 0.00209 18-Dec R.IPDEIIDMVK.E "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1171.6159 2.02 5650 18907 2 1171.617661 586.8152 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 4.03 3606.5 - 1.84E+06 - - - 1.5355 - 1.952 0.393 - 391 1 2 0 0.0018 10 0 0 0 7.73E+07 3.82E+07 - - - 3.8101 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18911.18911.2 0.000225 24-Nov R.LIEETISIAMATK[136.11].E "sp|O95249|GOSR1_HUMAN,tr|E9PCW1|E9PCW1_HUMAN,tr|G5E9T8|G5E9T8_HUMAN" 3 1426.7833 0.75 5654 18911 2 1426.785988 714.3989 Golgi SNAP receptor complex member 1 OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 4.53 3607 - 646287 - - - 1.9064 - 2.047 0.408 - 290.9 1 2 0 0.0027 13 0 0 0 5.92E+06 7.92E+06 - - - 3.8922 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.18913.18913.2 0.000278 20-Aug R.SLMIQTLEAVK[136.11].R "sp|Q9Y2R9|RT07_HUMAN,tr|J3QKW2|J3QKW2_HUMAN,tr|J3QLS3|J3QLS3_HUMAN,tr|J3QQS1|J3QQS1_HUMAN,tr|J3KSI8|J3KSI8_HUMAN" 5 1239.6988 1.03 5655 18913 2 1239.699486 620.8567 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 5.72 3607.2 - 1.07E+06 - - - 0.5453 - 1.849 0.385 - 170.3 1 2 0 0.0007 11 0 0 0 1.22E+07 1.17E+07 - - - 3.5472 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.18916.18916.2 0.0159 18-Aug R.LWTPPEDYR[166.11]L.- "sp|Q9BYD1|RM13_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 2 1298.6535 1.56 5657 18916 2 1298.654247 650.334 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.37 3607.6 - 698466 - - - 0.6076 - 1.831 0.273 - 288.6 1 2 0 0.0008 10 0 0 0 3.05E+07 1.95E+07 - - - 2.7455 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.18917.18917.2 0.000663 18-Aug R.YDLGGLVMVK.D sp|Q15274|NADC_HUMAN 1 1093.5842 0.45 5658 18917 2 1093.588329 547.7994 Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Homo sapiens OX=9606 GN=QPRT PE=1 SV=3 5.83 3607.6 - 3.82E+06 - - - 3.8058 - 1.638 0.449 - 151.8 1 2 0 0.0042 10 0 0 0 5.74E+07 1.28E+08 - - - 3.7334 0.9585 230117_WJC_METTL3_WT_vs_EV_F01.18918.18918.2 0.0487 16-Aug R.MVNHFIAEF.K "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1106.5219 - 5659 18918 2 1106.524516 554.2682 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.22 3607.7 - 2.85E+06 - - - 2.3633 - 1.818 0.366 - 240.4 1 1 0 0.0026 9 0 0 0 - - - - - 3.4727 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18919.18919.2 0.0448 18-Nov R.FEELC[160.03]SDLFR.S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1314.5914 50.31 5660 18919 2 1314.592999 658.303 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.14 3607.8 - 1.61E+06 - - - 1.1874 - 1.928 0.345 - 391.6 1 2 0 0.0016 10 0 0 0 1.50E+07 2.99E+05 - - - 3.4211 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18920.18920.2 0.000343 20-Oct R.SLMIQTLEAVK.R "sp|Q9Y2R9|RT07_HUMAN,tr|J3QKW2|J3QKW2_HUMAN,tr|J3QLS3|J3QLS3_HUMAN,tr|J3QQS1|J3QQS1_HUMAN,tr|J3KSI8|J3KSI8_HUMAN" 5 1231.6846 1.03 5661 18920 2 1231.68813 616.8496 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 5.72 3607.9 - 1.25E+06 - - - 2.8579 - 1.985 0.389 - 312.6 1 2 0 0.0035 11 0 0 0 1.22E+07 1.17E+07 - - - 3.7678 0.998 230117_WJC_METTL3_WT_vs_EV_F01.18922.18922.2 0.111 16-Sep R.TFVLEVMGR.H "sp|Q01813|PFKAP_HUMAN,sp|P17858|PFKAL_HUMAN,sp|P08237|PFKAM_HUMAN,tr|A0A2R8Y891|A0A2R8Y891_HUMAN,tr|Q5VSR5|Q5VSR5_HUMAN,tr|F8VZI0|F8VZI0_HUMAN,tr|A0A7I2V3Z0|A0A7I2V3Z0_HUMAN" 7 1050.5532 0.06 5663 18922 2 1050.556584 526.2839 "ATP-dependent 6-phosphofructokinase, platelet type OS=Homo sapiens OX=9606 GN=PFKP PE=1 SV=2" 5.66 3608.2 - 710762 - - - 3.2193 - 1.774 0.238 - 259.6 1 2 0 0.0034 9 0 0 0 1.04E+07 1.79E+08 - - - 2.4562 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18923.18923.2 0.000338 20-Oct K.FLEMC[160.03]NDLLAR[166.11].V "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1390.6613 7.43 5664 18923 2 1390.662961 696.3379 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.37 3608.3 - 638401 - - - 1.2217 - 1.992 0.43 - 328.6 1 2 0 0.0017 11 0 0 0 4.92E+07 6.62E+06 - - - 4.0807 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.18924.18924.2 0.00191 18-Aug K.LYGEFADPFK.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1185.5706 1.85 5665 18924 2 1185.574695 593.7926 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3608.5 - 469008 - - - 3.4321 - 1.484 0.396 - 152.4 1 2 0 0.0041 10 0 0 0 2.24E+07 1.21E+07 - - - 3.0664 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18925.18925.2 0.000272 22-Nov K.IIATVLMTEDIK[136.11].L "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 1353.7669 0.17 5666 18925 2 1353.768947 677.8907 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 3608.6 - 402348 - - - 1.5202 - 2.28 0.408 - 258.4 1 2 0 0.0021 12 0 0 0 2.12E+06 1.25E+07 - - - 4.2224 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.18929.18929.2 0.0364 12-Jun R.VLVWDLR.N "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 899.5229 1.52 5669 18929 2 899.524974 450.7687 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.81 3609.1 - 1.05E+06 - - - 2.319 - 1.467 0.34 - 214.2 1 2 0 0.0021 7 0 0 0 8.92E+07 5.86E+07 - - - 2.7658 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.18930.18930.2 0.197 12-Jul K.LIFYDLR[166.11].G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 948.5308 1.18 5670 18930 2 948.532485 475.2727 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3609.1 - 866526 - - - 1.7522 - 1.444 0.254 - 188.7 1 2 0 0.0017 7 0 0 0 7.66E+07 6.47E+07 - - - 2.0807 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18931.18931.2 0.000327 16-Aug R.SPTWFGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1059.5502 0.94 5671 18931 2 1059.551701 530.7824 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3609.2 - 2.13E+06 - - - 1.4497 - 1.825 0.397 - 358.1 1 2 0 0.0015 9 0 0 0 2.94E+08 3.12E+08 - - - 3.7132 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18935.18935.2 0.000282 16-Sep K.LFTTMELMR.W sp|O00232|PSD12_HUMAN 1 1140.5671 1.79 5675 18935 2 1140.568922 571.2908 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 6 3609.6 - 546717 - - - 1.565 - 1.879 0.424 - 243.1 1 2 0 0.0018 9 0 0 0 3.39E+07 1.89E+07 - - - 3.9969 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.18939.18939.2 0.0069 14-Aug K.FEFLGINR.Q sp|Q8N3X1|FNBP4_HUMAN 1 994.5236 1.64 5679 18939 2 994.524046 498.2691 Formin-binding protein 4 OS=Homo sapiens OX=9606 GN=FNBP4 PE=1 SV=3 6 3610.2 - 338809 - - - 0.4324 - 1.79 0.267 - 197.9 1 2 0 0.0004 8 0 0 0 1.54E+07 9.38E+06 - - - 2.7689 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.18950.18950.2 0.31 16-Oct K.ELIEELIAK[136.11].S "sp|P78316|NOP14_HUMAN,tr|E9PFK5|E9PFK5_HUMAN" 2 1064.6209 0.76 5688 18950 2 1064.621324 533.3177 Nucleolar protein 14 OS=Homo sapiens OX=9606 GN=NOP14 PE=1 SV=3 4.25 3611.5 - 6.66E+06 - - - 0.4199 - 2.071 0.275 - 322.2 1 2 0 0.0004 9 0 0 0 4.67E+07 6.13E+07 - - - 3.1782 0.9914 230117_WJC_METTL3_WT_vs_EV_F01.18958.18958.2 0.151 12-Aug K.LYSLFLK.Y "sp|Q9P2R7|SUCB1_HUMAN,tr|Q5T9Q5|Q5T9Q5_HUMAN,tr|A0A0U1RRI1|A0A0U1RRI1_HUMAN,tr|A0A2R8YDQ9|A0A2R8YDQ9_HUMAN,tr|A0A2R8Y6Y7|A0A2R8Y6Y7_HUMAN,tr|Q5T9Q8|Q5T9Q8_HUMAN" 6 882.5215 2.91 5694 18958 2 882.521189 442.268 "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLA2 PE=1 SV=3" 8.59 3612.2 - 1.15E+06 - - - -0.3422 - 1.311 0.15 - 203.7 1 2 0 -0.0003 7 0 0 0 2.12E+07 7.27E+06 - - - 1.0068 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.18959.18959.2 0.00537 16-Jul K.LFTTMELMR[166.11].W sp|O00232|PSD12_HUMAN 1 1150.5754 1.8 5695 18959 2 1150.579431 576.295 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 6 3612.3 - 1.12E+06 - - - 3.4974 - 1.581 0.407 - 108.4 1 2 0 0.004 9 0 0 0 3.37E+07 1.87E+07 - - - 3.371 0.992 230117_WJC_METTL3_WT_vs_EV_F01.18963.18963.2 0.381 12-Jul R.NLPFLIK.K sp|Q86TB9|PATL1_HUMAN 1 843.5218 1.24 5699 18963 2 843.523177 422.7682 Protein PAT1 homolog 1 OS=Homo sapiens OX=9606 GN=PATL1 PE=1 SV=2 8.75 3612.7 - 645628 - - - 1.6028 - 1.129 0.164 - 159.3 1 2 0 0.0014 7 0 0 0 2.14E+07 1.73E+07 - - - 0.6363 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.18968.18968.2 5.49E-06 20-Dec K.IGDFGLVTSLK.N "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 3 1148.6441 64.73 5702 18968 2 1148.646213 575.3293 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 5.84 3613.2 - 1.98E+06 - - - 1.8178 - 2.449 0.275 - 272.3 1 2 0 0.0021 11 0 0 0 5.08E+07 7.85E+05 - - - 3.4945 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.18969.18969.2 0.073 16-Nov R.ALVAVLLSR.T sp|Q92616|GCN1_HUMAN 1 940.607 1.06 5703 18969 2 940.60681 471.3108 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.79 3613.4 - 1.37E+06 - - - -0.151 - 2.189 0.181 - 467.4 1 2 0 -0.0001 9 0 0 0 2.04E+07 1.92E+07 - - - 2.6444 0.9865 230117_WJC_METTL3_WT_vs_EV_F01.18972.18972.2 0.582 12-Jul R.YILDYLR[166.11].D "sp|Q96CX2|KCD12_HUMAN,sp|Q68DU8|KCD16_HUMAN" 2 964.5257 2.21 5706 18972 2 964.525962 483.2701 BTB\POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1 5.83 3613.8 - 328349 - - - 0.2322 - 1.325 0.07 - 183.2 1 2 0 0.0002 7 0 0 0 2.94E+07 1.33E+07 - - - 0.4496 0.9272 230117_WJC_METTL3_WT_vs_EV_F01.18976.18976.2 0.0218 14-Jun K.NSLESYAF.N "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 929.4131 - 5707 18976 2 929.412419 465.7138 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4 3614.2 - 2.16E+06 - - - -0.6929 - 1.298 0.484 - 113.8 1 1 0 -0.0006 8 0 0 0 - - - - - 3.4023 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.18977.18977.2 0.286 18-Jul R.ILVATNLFGR.G "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 6 1102.6499 1.32 5708 18977 2 1102.650489 552.3322 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 9.75 3614.3 - 1.00E+07 - - - 0.5532 - 1.446 0.268 - 149 1 2 0 0.0006 10 0 0 0 4.56E+08 3.47E+08 - - - 2.0497 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.18979.18979.2 0.952 16-Nov R.ALVAVLLSR[166.11].T sp|Q92616|GCN1_HUMAN 1 950.6152 1.07 5710 18979 2 950.615242 476.3149 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.79 3614.4 - 2.55E+06 - - - 0.021 - 2.041 0.103 - 600.3 1 2 0 0 9 0 0 0 2.06E+07 1.92E+07 - - - 1.8658 1 230117_WJC_METTL3_WT_vs_EV_F01.18980.18980.2 6.53E-06 20-Oct K.LYLNETFSELR.L "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C3Z5|H7C3Z5_HUMAN" 3 1383.7034 4.24 5711 18980 2 1383.704203 692.859 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 4.53 3614.5 - 1.15E+06 - - - 0.5579 - 2.464 0.533 - 340.5 1 2 0 0.0008 11 0 0 0 8.85E+06 2.09E+06 - - - 5.417 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.18987.18987.2 0.806 16-Sep K.GLALWEAYR.E "sp|Q15020|SART3_HUMAN,tr|F8VVK9|F8VVK9_HUMAN,tr|A0A494C0L2|A0A494C0L2_HUMAN,tr|F8W667|F8W667_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN,tr|F8VZM2|F8VZM2_HUMAN" 6 1077.5607 3.45 5717 18987 2 1077.561413 539.7876 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 3615.5 - 3.44E+06 - - - 0.6338 - 1.998 0.246 - 474.2 1 2 0 0.0007 9 0 0 0 3.38E+07 9.79E+06 - - - 2.8602 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.18989.18989.2 0.0204 16-Oct R.YLTVAAVFR.G "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 5 1038.5862 2.87 5718 18989 2 1038.587048 520.3004 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3615.7 - 2.34E+06 - - - 0.8011 - 1.883 0.439 - 346.6 1 2 0 0.0008 9 0 0 0 1.26E+09 4.39E+08 - - - 4.1141 0.9894 230117_WJC_METTL3_WT_vs_EV_F01.18996.18996.2 0.0926 14-Jul K.TIWSTMLR.L "sp|Q16850|CP51A_HUMAN,tr|H7C0D0|H7C0D0_HUMAN" 2 1006.527 1.39 5725 18996 2 1006.527788 504.2708 Lanosterol 14-alpha demethylase OS=Homo sapiens OX=9606 GN=CYP51A1 PE=1 SV=4 9.41 3616.4 - 449930 - - - 0.7958 - 1.061 0.17 - 91.3 1 2 0 0.0008 8 0 0 0 6.02E+06 4.32E+06 - - - 0.4749 1 230117_WJC_METTL3_WT_vs_EV_F01.19001.19001.2 0.00907 20-Oct K.FLC[160.03]YLSQAGFR.V sp|Q7Z2T5|TRM1L_HUMAN 1 1360.6598 1.21 5730 19001 2 1360.657143 681.3372 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 8.22 3617.1 - 186214 - - - -1.9468 - 2.234 0.466 - 406.3 1 2 0 -0.0026 11 0 0 0 1.08E+07 8.98E+06 - - - 4.6565 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19004.19004.2 0.00116 20-Nov K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 0.95 5731 19004 2 1197.720631 599.8679 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3617.5 - 8.80E+06 - - - -0.5252 - 2.364 0.427 - 515.7 1 2 0 -0.0006 11 0 0 0 1.47E+09 1.55E+09 - - - 4.5221 1 230117_WJC_METTL3_WT_vs_EV_F01.19005.19005.2 4.31E-08 14/20 K.VANVSLLALYK.G sp|P62266|RS23_HUMAN 1 1189.7071 0.95 5732 19005 2 1189.706727 595.8608 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3617.5 - 6.98E+06 - - - -0.2799 - 2.798 0.471 - 947 1 2 0 -0.0003 11 0 0 0 1.47E+09 1.55E+09 - - - 5.3031 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.19007.19007.2 1.28E-05 24-Nov K.AEPLLGAPGELLK.Q sp|P17482|HXB9_HUMAN 1 1306.7497 2.58 5734 19007 2 1306.746047 654.3821 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 3617.8 - 740777 - - - -2.7595 - 2.1 0.484 - 340.8 1 2 0 -0.0036 13 0 0 0 2.72E+07 1.06E+07 - - - 4.5189 0.9918 230117_WJC_METTL3_WT_vs_EV_F01.19010.19010.2 0.246 12-Jul R.FVLNLIK[136.11].L sp|Q8TDN6|BRX1_HUMAN 1 853.5517 0.76 5737 19010 2 853.552923 427.7831 Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2 8.75 3618.2 - 286129 - - - 1.4621 - 1.319 0.094 - 123.8 1 2 0 0.0012 7 0 0 0 5.76E+07 7.55E+07 - - - 0.6122 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.19013.19013.2 0.0634 14-Jul K.TVALWDLR[166.11].N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 982.5475 1.98 5738 19013 2 982.547398 492.281 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3618.6 - 9.83E+06 - - - -0.1405 - 1.311 0.24 - 178.4 1 2 0 -0.0001 8 0 0 0 8.60E+08 4.34E+08 - - - 1.6303 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.19015.19015.2 0.339 14-Jul K.TVALWDLR.N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 972.5393 1.98 5740 19015 2 972.538544 487.2769 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3618.8 - 1.59E+07 - - - -0.7424 - 1.454 0.281 - 201.1 1 2 0 -0.0007 8 0 0 0 8.60E+08 4.34E+08 - - - 2.2452 0.995 230117_WJC_METTL3_WT_vs_EV_F01.19021.19021.2 0.019 20-Oct K.FLC[160.03]YLSQAGFR[166.11].V sp|Q7Z2T5|TRM1L_HUMAN 1 1370.6681 1.21 5746 19021 2 1370.674409 686.3413 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 8.22 3619.4 - 1.04E+06 - - - 4.6306 - 1.582 0.295 - 239.5 1 2 0 0.0063 11 0 0 0 1.08E+07 8.98E+06 - - - 2.4587 0.9928 230117_WJC_METTL3_WT_vs_EV_F01.19022.19022.2 0.0498 12-Aug R.FVLNLIK.L sp|Q8TDN6|BRX1_HUMAN 1 845.5375 0.76 5747 19022 2 845.536408 423.776 Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2 8.75 3619.5 - 1.02E+06 - - - -1.2619 - 1.576 0.153 - 185.1 1 2 0 -0.0011 7 0 0 0 5.76E+07 7.55E+07 - - - 1.6121 1 230117_WJC_METTL3_WT_vs_EV_F01.19023.19023.2 1.27E-05 22-Dec K.SLAMEMVLTGDR.L sp|P30084|ECHM_HUMAN 1 1321.637 1.66 5748 19023 2 1321.637651 661.8258 "Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4" 4.37 3619.6 - 877631 - - - 0.4865 - 2.502 0.493 - 323.1 1 2 0 0.0006 12 0 0 0 9.85E+06 5.93E+06 - - - 5.0951 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.19030.19030.2 0.0405 22-Jul K.FGEAIGMGFPVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1259.6464 1.01 5754 19030 2 1259.646511 630.8305 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3620.5 - 658029 - - - 0.104 - 1.42 0.292 - 56.3 2 2 0 0.0001 12 0 0 0 1.66E+08 1.64E+08 - - - 1.9858 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.19032.19032.2 0.225 16-Nov R.LDALLAELR.A sp|Q96L58|B3GT6_HUMAN 1 1012.5917 0.95 5756 19032 2 1012.591411 507.3031 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 4.37 3620.7 - 1.83E+06 - - - -0.2815 - 2.6 0.188 - 471.2 1 2 0 -0.0003 9 0 0 0 2.36E+07 2.48E+07 - - - 3.1938 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19034.19034.2 1.70E-05 20-Nov R.LAVDLSEVVIK.W "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1184.7016 0.24 5758 19034 2 1184.701557 593.3581 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.37 3621 - 1.67E+06 - - - -0.0701 - 2.367 0.385 - 321.5 1 2 0 -0.0001 11 0 0 0 2.34E+07 9.85E+07 - - - 4.2155 1 230117_WJC_METTL3_WT_vs_EV_F01.19037.19037.2 3.85E-05 22-Dec K.SLAMEMVLTGDR[166.11].L sp|P30084|ECHM_HUMAN 1 1331.6453 1.66 5761 19037 2 1331.648901 666.8299 "Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4" 4.37 3621.4 - 621399 - - - 2.7207 - 2.452 0.521 - 572.2 1 2 0 0.0036 12 0 0 0 9.85E+06 5.93E+06 - - - 5.2479 1 230117_WJC_METTL3_WT_vs_EV_F01.19041.19041.2 1.16E-05 18-Oct R.FEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1252.6088 11.42 5763 19041 2 1252.609225 627.3117 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3621.9 - 1.10E+07 - - - 0.3377 - 2.149 0.595 - 373.3 1 2 0 0.0004 10 0 0 0 1.09E+09 9.56E+07 - - - 5.5709 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19042.19042.2 0.194 18-Oct R.FLLQDTVELR[166.11].E "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1242.6848 1.85 5764 19042 2 1242.685086 622.3497 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3621.9 - 6.22E+06 - - - 0.2639 - 2.065 0.414 - 430.3 1 2 0 0.0003 10 0 0 0 2.32E+08 1.25E+08 - - - 4.1228 0.9846 230117_WJC_METTL3_WT_vs_EV_F01.19043.19043.2 12.4 12-Jul R.VLFLIPK.N "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q5JV98|Q5JV98_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|H0Y630|H0Y630_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 13 828.5473 2.18 5765 19043 2 828.5472 415.2809 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 8.72 3622 - 4.07E+06 - - - -0.1352 - 1.205 0.116 - 155.6 1 2 0 -0.0001 7 0 0 0 4.88E+07 2.23E+07 - - - 0.4886 0.999 230117_WJC_METTL3_WT_vs_EV_F01.19046.19046.2 0.0054 18-Dec K.IEVIEIMTDR[166.11].G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1227.6408 0.85 5768 19046 2 1227.639249 614.8277 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3622.2 - 1.63E+06 - - - -1.2992 - 2.52 0.344 - 658.1 1 2 0 -0.0016 10 0 0 0 2.21E+08 2.61E+08 - - - 4.1612 0.999 230117_WJC_METTL3_WT_vs_EV_F01.19053.19053.2 3.97E-05 20-Dec K.TPPPVLIFAEK.K sp|Q9UJV9|DDX41_HUMAN 1 1210.6962 1.59 5773 19053 2 1210.694313 606.3554 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3623.1 - 1.13E+06 - - - -1.5264 - 2.114 0.445 - 422.3 1 2 0 -0.0018 11 0 0 0 1.53E+08 9.57E+07 - - - 4.3523 0.9547 230117_WJC_METTL3_WT_vs_EV_F01.19054.19054.2 1.5 12-Jun K.WMGIAFR[166.11].L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 889.4508 1.16 5774 19054 2 889.449674 445.7327 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.75 3623.1 - 1.90E+06 - - - -1.2648 - 1.045 0.14 - 144 1 2 0 -0.0011 7 0 0 0 3.56E+07 3.06E+07 - - - 0.2142 0.999 230117_WJC_METTL3_WT_vs_EV_F01.19056.19056.2 0.109 18-Oct R.FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1262.6171 11.42 5776 19056 2 1262.616377 632.3158 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3623.3 - 714204 - - - -0.5504 - 2.043 0.295 - 416.8 1 2 0 -0.0007 10 0 0 0 1.09E+09 9.56E+07 - - - 3.2138 0.9728 230117_WJC_METTL3_WT_vs_EV_F01.19057.19057.2 0.00108 12-Jul L.SGFLVWR[166.11].R "sp|Q9NP84|TNR12_HUMAN,sp|Q96T88|UHRF1_HUMAN,tr|I3L1J9|I3L1J9_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 6 873.4736 1.36 5777 19057 2 873.474559 437.7441 Tumor necrosis factor receptor superfamily member 12A OS=Homo sapiens OX=9606 GN=TNFRSF12A PE=1 SV=1 9.47 3623.5 - 467562 - - - 1.0487 - 1.665 0.429 - 170 1 1 0 0.0009 7 0 0 0 2.26E+07 1.66E+07 - - - 3.8247 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19058.19058.2 0.00168 14/22 R.APGSGLALLPLK.L "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 1135.6965 8.67 5778 19058 2 1135.697373 568.8555 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 8.8 3623.6 - 129145 - - - 0.7731 - 2.065 0.274 - 287.5 1 2 0 0.0009 12 0 0 0 1.07E+07 1.24E+06 - - - 2.9724 0.9658 230117_WJC_METTL3_WT_vs_EV_F01.19059.19059.2 0.00162 24-Nov K.AEPLLGAPGELLK[136.11].Q sp|P17482|HXB9_HUMAN 1 1314.7639 2.64 5779 19059 2 1314.755681 658.3892 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 3623.7 - 0 - - - -6.2156 - 1.772 0.37 - 208.1 1 2 0 -0.0082 13 0 0 0 2.71E+07 1.03E+07 - - - 3.2396 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.19060.19060.3 0.0727 Sep-40 K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 1 5780 19060 3 1197.719867 400.2477 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3623.9 - 62714.1 - - - -1.163 - 1.951 0.209 - 84.5 1 2 0 -0.0014 11 0 0 0 6.01E+06 6.03E+06 - - - 2.7684 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19067.19067.2 0.000289 20-Dec R.IGFVGFPSVGK.S sp|Q9Y295|DRG1_HUMAN 1 1106.6124 1.71 5785 19067 2 1106.613975 554.3135 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 8.75 3624.7 - 4.49E+06 - - - 1.3952 - 2.006 0.439 - 412.5 1 2 0 0.0015 11 0 0 0 9.32E+07 5.45E+07 - - - 4.1662 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.19068.19068.2 0.738 14-Jul R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 0.74 5786 19068 2 898.523348 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 3624.8 - 1.42E+06 - - - -0.2983 - 1.508 0.26 - 105 1 2 0 -0.0003 8 0 0 0 1.66E+07 2.24E+07 - - - 2.2002 1 230117_WJC_METTL3_WT_vs_EV_F01.19069.19069.2 3.71E-08 15/24 M.PVAVMAESAFSFK.K "sp|Q99627|CSN8_HUMAN,tr|F8WEF2|F8WEF2_HUMAN,tr|E9PGT6|E9PGT6_HUMAN" 3 1382.6904 1.09 5787 19069 2 1382.689078 692.3525 COP9 signalosome complex subunit 8 OS=Homo sapiens OX=9606 GN=COPS8 PE=1 SV=1 6.43 3624.9 - 391777 - - - -0.9727 - 2.589 0.577 - 804 1 2 0 -0.0013 13 0 0 0 5.58E+06 5.10E+06 - - - 5.7438 0.9954 230117_WJC_METTL3_WT_vs_EV_F01.19073.19073.2 0.124 20-Sep K.TPPPVLIFAEK[136.11].K sp|Q9UJV9|DDX41_HUMAN 1 1218.7104 1.58 5789 19073 2 1218.71232 610.3625 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3625.4 - 8.76E+06 - - - 1.6074 - 1.061 0.251 - 131.1 1 2 0 0.002 11 0 0 0 1.51E+08 9.57E+07 - - - 1.0545 0.9935 230117_WJC_METTL3_WT_vs_EV_F01.19076.19076.2 0.0229 14-Jul R.DLTDYLMK[136.11].L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 1005.4932 1.12 5792 19076 2 1005.491839 503.7539 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3625.7 - 418255 - - - -1.3874 - 1.331 0.254 - 146.2 1 2 0 -0.0014 8 0 0 0 5.50E+07 4.91E+07 - - - 1.779 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19079.19079.2 0.000609 24-Nov R.ILLAEVPTMAVEK[136.11].V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1420.8091 5.9 5793 19079 2 1420.810691 711.4118 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3626.1 - 540419 - - - 1.1275 - 2.099 0.418 - 354.5 1 2 0 0.0016 13 0 0 0 4.98E+07 8.45E+06 - - - 4.0308 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.19083.19083.2 0.0524 14-Jul R.DFVNYLVR[166.11].L sp|Q08211|DHX9_HUMAN 1 1034.5425 0.87 5796 19083 2 1034.543845 518.2785 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.84 3626.5 - 3.66E+07 - - - 1.3475 - 1.443 0.352 - 192.6 1 2 0 0.0014 8 0 0 0 3.37E+08 3.89E+08 - - - 2.7465 0.9839 230117_WJC_METTL3_WT_vs_EV_F01.19085.19085.2 0.0972 16-Jun R.YQFTPAFLR.L "sp|Q13432|U119A_HUMAN,sp|A6NIH7|U119B_HUMAN,tr|K7EN86|K7EN86_HUMAN,tr|C9JSK0|C9JSK0_HUMAN,tr|K7EJU3|K7EJU3_HUMAN" 5 1141.592 1.32 5798 19085 2 1141.597826 571.8033 Protein unc-119 homolog A OS=Homo sapiens OX=9606 GN=UNC119 PE=1 SV=1 8.75 3626.7 - 438462 - - - 5.0771 - 1.397 0.22 - 94.4 1 2 0 0.0058 9 0 0 0 3.57E+06 2.70E+06 - - - 1.6313 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19106.19106.2 0.15 16-Sep R.VEFILEQMR.L sp|O00232|PSD12_HUMAN 1 1163.6009 1.75 5816 19106 2 1163.60103 582.8077 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.53 3629.1 - 907315 - - - 0.1289 - 2.055 0.391 - 349.9 1 2 0 0.0001 9 0 0 0 1.70E+07 9.72E+06 - - - 4.0127 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19109.19109.2 0.000134 16-Sep K.GLDFALLQK[136.11].V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1011.5844 1.35 5818 19109 2 1011.585186 506.7995 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3629.4 - 572477 - - - 0.7454 - 1.882 0.458 - 246.5 1 2 0 0.0008 9 0 0 0 3.41E+07 2.53E+07 - - - 4.2529 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.19111.19111.3 0.00107 16/40 R.ILVTLLHTLER.M sp|Q9BWD1|THIC_HUMAN 1 1306.7973 1.36 5820 19111 3 1306.798474 436.6064 "Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2" 6.75 3629.6 - 675345 - - - 0.9198 - 2.816 0.405 - 462.6 1 2 0 0.0012 11 0 0 0 8.59E+06 6.31E+06 - - - 5.9962 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19112.19112.2 0.000603 12-Jul K.DYVDLFR.H sp|P78527|PRKDC_HUMAN 1 926.4498 0.33 5821 19112 2 926.451179 464.2322 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.21 3629.7 - 554161 - - - 1.5079 - 1.382 0.396 - 221.7 1 2 0 0.0014 7 0 0 0 1.45E+07 4.44E+07 - - - 2.9905 0.9927 230117_WJC_METTL3_WT_vs_EV_F01.19113.19113.2 0.0332 16-Jul K.ITPLMAAFR.K "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1018.5634 2.93 5822 19113 2 1018.56539 510.289 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 9.75 3629.8 - 373940 - - - 1.9812 - 1.543 0.093 - 133.2 3 2 0 0.002 9 0 0 0 1.23E+07 4.22E+06 - - - 0.7689 0.999 230117_WJC_METTL3_WT_vs_EV_F01.19116.19116.2 5.24E-05 26-Oct K.LNLVDLAGSENIGR.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1469.7838 0.01 5825 19116 2 1469.782261 735.8992 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 3630.2 - 0 - - - -1.0519 - 2.019 0.402 - 213.7 1 2 0 -0.0015 14 0 0 0 1.02E+06 8.94E+07 - - - 3.7728 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19121.19121.2 3.40E-06 22-Dec K.IIENELEGFGIR.L sp|Q9Y295|DRG1_HUMAN 1 1388.73 1.38 5828 19121 2 1388.731323 695.3723 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3630.8 - 143631 - - - 0.9671 - 2.569 0.412 - 508.6 1 2 0 0.0013 12 0 0 0 1.01E+07 7.29E+06 - - - 4.5662 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19124.19124.2 9.56E-05 22-Sep K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 3.29 5831 19124 2 1263.691749 632.853 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3630.9 - 244080 - - - 0.2635 - 1.91 0.481 - 130 1 2 0 0.0003 12 0 0 0 1.92E+07 5.82E+06 - - - 4.2962 1 230117_WJC_METTL3_WT_vs_EV_F01.19125.19125.3 0.000291 14/40 R.ILVTLLHTLER[166.11].M sp|Q9BWD1|THIC_HUMAN 1 1316.8055 1.36 5832 19125 3 1316.807554 439.9425 "Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2" 6.75 3631 - 96819.6 - - - 1.5279 - 2.93 0.471 - 460.4 1 2 0 0.002 11 0 0 0 8.59E+06 6.31E+06 - - - 6.8445 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.19128.19128.2 0.00175 16-Sep K.GFGFVSFER[166.11].H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1054.5112 0.97 5833 19128 2 1054.507889 528.2629 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3631.4 - 1.57E+06 - - - -3.0934 - 1.753 0.425 - 264.3 1 2 0 -0.0033 9 0 0 0 4.81E+08 4.98E+08 - - - 3.803 1 230117_WJC_METTL3_WT_vs_EV_F01.19129.19129.2 5.34E-07 16/20 M.PPYTVVYFPVR.G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1336.718 1.15 5834 19129 2 1336.719432 669.3663 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3631.5 - 612472 - - - 1.102 - 2.881 0.562 - 1246.9 1 2 0 0.0015 11 0 0 0 6.51E+07 5.66E+07 - - - 6.054 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.19130.19130.2 0.0343 14-Oct R.ITNWLVLK.N "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN,tr|H3BRT3|H3BRT3_HUMAN" 3 985.5961 2.14 5835 19130 2 985.599822 493.8053 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 8.75 3631.7 - 541092 - - - 3.8241 - 1.745 0.239 - 202.5 1 2 0 0.0038 8 0 0 0 5.36E+06 2.50E+06 - - - 2.4842 1 230117_WJC_METTL3_WT_vs_EV_F01.19131.19131.2 6.11E-08 18/20 M.PPYTVVYFPVR[166.11].G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1346.7262 1.14 5836 19131 2 1346.732149 674.3704 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3631.8 - 497722 - - - 4.3958 - 2.996 0.509 - 912.1 1 2 0 0.0059 11 0 0 0 6.51E+07 5.72E+07 - - - 5.767 0.9225 230117_WJC_METTL3_WT_vs_EV_F01.19134.19134.2 0.819 16-May K.ILVTPWDYR.L sp|Q8TF46|DI3L1_HUMAN 1 1161.6182 0.05 5839 19134 2 1161.622773 581.8164 DIS3-like exonuclease 1 OS=Homo sapiens OX=9606 GN=DIS3L PE=1 SV=2 5.84 3632.2 - 365685 - - - 3.898 - 1.206 0.066 - 60.6 3 2 0 0.0045 9 0 0 0 2.01E+06 4.45E+07 - - - -0.1442 1 230117_WJC_METTL3_WT_vs_EV_F01.19135.19135.2 0.00126 24-Dec R.LDYLGVSYGLTPR[166.11].L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1462.7695 0.83 5840 19135 2 1462.772769 732.3921 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.83 3632.3 - 312210 - - - 2.2006 - 2.277 0.491 - 288.5 1 2 0 0.0032 13 0 0 0 1.65E+06 1.99E+06 - - - 4.7784 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19137.19137.2 4.09E-06 22-Dec K.YMGAAAMYLISK.R "sp|Q9H7Z7|PGES2_HUMAN,tr|A0A7I2V5T7|A0A7I2V5T7_HUMAN,tr|A6NHH0|A6NHH0_HUMAN,tr|X6RJ95|X6RJ95_HUMAN,tr|A0A7I2V5X6|A0A7I2V5X6_HUMAN" 5 1317.6461 3.12 5842 19137 2 1317.648817 659.8303 Prostaglandin E synthase 2 OS=Homo sapiens OX=9606 GN=PTGES2 PE=1 SV=1 8.5 3632.6 - 243120 - - - 2.0499 - 1.903 0.514 - 288.8 1 2 0 0.0027 12 0 0 0 2.80E+06 8.99E+05 - - - 4.5295 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19140.19140.2 0.00657 20-Jul R.YLLEQDFPGMR.L "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN" 2 1367.6544 2.74 5845 19140 2 1367.654516 684.8345 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.37 3633 - 128924 - - - 0.1053 - 1.645 0.351 - 144.7 1 2 0 0.0001 11 0 0 0 4.19E+06 1.53E+06 - - - 2.9799 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.19143.19143.2 7.38E-05 14-Aug R.DFVNYLVR.L sp|Q08211|DHX9_HUMAN 1 1024.5342 0.87 5847 19143 2 1024.537757 513.2744 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.84 3633.3 - 7.58E+06 - - - 3.4904 - 1.655 0.419 - 270.5 1 2 0 0.0036 8 0 0 0 3.37E+08 3.89E+08 - - - 3.6541 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19145.19145.2 1.55E-05 16-Oct K.GFGFVSFER.H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1044.5029 0.97 5849 19145 2 1044.505709 523.2587 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3633.4 - 8.40E+06 - - - 2.7075 - 1.833 0.458 - 405.7 1 2 0 0.0028 9 0 0 0 4.81E+08 4.98E+08 - - - 4.176 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19146.19146.2 0.00412 16-Sep K.GLDFALLQK.V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1003.5702 1.05 5850 19146 2 1003.573161 502.7924 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3633.4 - 4.45E+06 - - - 2.9186 - 1.874 0.464 - 221.3 1 2 0 0.0029 9 0 0 0 3.31E+07 3.17E+07 - - - 4.2842 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19147.19147.2 0.000726 16-Aug R.SPTWFGIPR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1069.5584 1 5851 19147 2 1069.560761 535.7865 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3633.5 - 1.96E+06 - - - 2.1747 - 1.682 0.366 - 333.2 1 2 0 0.0023 9 0 0 0 3.08E+08 3.07E+08 - - - 3.2479 1 230117_WJC_METTL3_WT_vs_EV_F01.19148.19148.2 6.12E-05 14/24 R.ILLAEVPTMAVEK.V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1412.7949 5.9 5852 19148 2 1412.798011 707.4047 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3633.6 - 1.83E+06 - - - 2.2098 - 2.485 0.464 - 589.4 1 2 0 0.0031 13 0 0 0 4.98E+07 8.45E+06 - - - 4.8034 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19149.19149.2 0.0029 14-Sep K.IDILTELR[166.11].D "sp|O00139|KIF2A_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 981.5734 1.14 5853 19149 2 981.575821 491.794 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.37 3633.6 - 1.57E+06 - - - 2.4491 - 2.01 0.317 - 280.1 1 2 0 0.0024 8 0 0 0 6.84E+07 5.98E+07 - - - 3.4871 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19151.19151.2 0.00917 18-Sep K.LEPAFLSGLR.C "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1101.6182 1.93 5855 19151 2 1101.620942 551.8164 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3633.8 - 1.18E+06 - - - 2.4482 - 1.982 0.425 - 261.8 1 2 0 0.0027 10 0 0 0 3.46E+07 1.79E+07 - - - 4.0888 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.19152.19152.2 0.0103 20-Sep R.TVPILFASTVR.R sp|Q6P1M0|S27A4_HUMAN 1 1202.7023 0.3 5856 19152 2 1202.706568 602.3584 Long-chain fatty acid transport protein 4 OS=Homo sapiens OX=9606 GN=SLC27A4 PE=1 SV=1 9.41 3633.8 - 987164 - - - 3.5412 - 1.658 0.363 - 274.2 1 2 0 0.0043 11 0 0 0 1.05E+07 3.45E+07 - - - 3.0886 1 230117_WJC_METTL3_WT_vs_EV_F01.19153.19153.2 0.00113 14/20 K.MALDIEIATYR[166.11].K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1304.6674 1.44 5857 19153 2 1304.678388 653.341 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3633.9 - 967444 - - - 8.4274 - 2.863 0.493 - 894.7 1 2 0 0.011 11 0 0 0 1.56E+08 1.09E+08 - - - 5.5244 0.996 230117_WJC_METTL3_WT_vs_EV_F01.19154.19154.2 0.173 16-Nov K.LTQILSYLR[166.11].Q sp|Q13123|RED_HUMAN 1 1115.6578 1.45 5858 19154 2 1115.664685 558.8362 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3634 - 942013 - - - 6.1578 - 2.323 0.408 - 550 1 2 0 0.0069 9 0 0 0 1.05E+08 7.24E+07 - - - 4.4908 0.995 230117_WJC_METTL3_WT_vs_EV_F01.19156.19156.2 0.000152 20-Nov R.LEPLVNDLTLR.L sp|Q70UQ0|IKIP_HUMAN 1 1281.7293 1.79 5860 19156 2 1281.737228 641.8719 Inhibitor of nuclear factor kappa-B kinase-interacting protein OS=Homo sapiens OX=9606 GN=IKBIP PE=1 SV=1 4.37 3634.2 - 252022 - - - 6.2228 - 2.155 0.393 - 552 1 2 0 0.008 11 0 0 0 1.64E+07 9.15E+06 - - - 4.0182 0.9919 230117_WJC_METTL3_WT_vs_EV_F01.19157.19157.2 0.317 12-May K.LGDLFFR.V "sp|Q70EL1|UBP54_HUMAN,tr|H7C1E9|H7C1E9_HUMAN,tr|A0A7P0T9N2|A0A7P0T9N2_HUMAN,tr|A0A7P0T9K1|A0A7P0T9K1_HUMAN,tr|A0A804D9U3|A0A804D9U3_HUMAN" 5 866.465 2.3 5861 19157 2 866.46586 434.2398 Inactive ubiquitin carboxyl-terminal hydrolase 54 OS=Homo sapiens OX=9606 GN=USP54 PE=1 SV=4 5.84 3634.4 - 228343 - - - 0.9487 - 1.331 0.095 - 55.4 1 2 0 0.0008 7 0 0 0 2.04E+06 8.89E+05 - - - 0.6484 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19161.19161.2 0.0122 18-Sep K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.21 5864 19161 2 1086.645865 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3634.8 - 1.02E+06 - - - 1.9638 - 1.674 0.297 - 223.8 1 2 0 0.0021 10 0 0 0 5.75E+08 4.75E+08 - - - 2.6721 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19164.19164.2 0.00281 16-Nov K.LTQILSYLR.Q sp|Q13123|RED_HUMAN 1 1105.6495 1.45 5866 19164 2 1105.651527 553.832 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3635.1 - 2.95E+06 - - - 1.7926 - 2.263 0.378 - 577.4 1 2 0 0.002 9 0 0 0 1.05E+08 7.24E+07 - - - 4.195 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19165.19165.2 7.16E-05 22-Oct K.NIEDVIAQGIGK.L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1255.6772 2.75 5867 19165 2 1255.680041 628.8459 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3635.2 - 911800 - - - 2.2498 - 2.182 0.462 - 214.8 1 2 0 0.0028 12 0 0 0 4.71E+06 1.71E+06 - - - 4.5054 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.19168.19168.3 0.00334 Oct-36 R.DFLLK[136.11]PELLR[166.11].A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1260.7561 1.19 5870 19168 3 1260.757669 421.2593 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3635.4 - 662431 - - - 1.2611 - 2.144 0.442 - 121.2 1 2 0 0.0016 10 0 0 0 3.95E+07 3.33E+07 - - - 5.6948 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19170.19170.2 0.000773 18-Oct K.C[160.03]LEEFELLGK.A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1236.606 1.02 5872 19170 2 1236.609604 619.3103 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3635.6 - 579079 - - - 2.8942 - 1.857 0.437 - 276.6 1 2 0 0.0036 10 0 0 0 9.93E+06 9.75E+06 - - - 3.9953 0.9061 230117_WJC_METTL3_WT_vs_EV_F01.19171.19171.2 0.0157 22-Jul K.GPAVGIDLGTTY.S "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1162.587 - 5873 19171 2 1162.587357 582.3008 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 3.8 3635.7 - 532700 - - - 0.3036 - 1.362 0.339 - 144 1 1 0 0.0004 12 0 0 0 - - - - - 2.3577 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19173.19173.2 0.0401 18-Nov R.LLLDTLQLSK.- "sp|O15357|SHIP2_HUMAN,tr|H7BXR2|H7BXR2_HUMAN" 2 1142.6911 1.51 5875 19173 2 1142.693665 572.3528 "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 OS=Homo sapiens OX=9606 GN=INPPL1 PE=1 SV=2" 5.84 3635.9 - 436513 - - - 2.2666 - 2.089 0.384 - 268.6 1 2 0 0.0026 10 0 0 0 9.61E+06 6.36E+06 - - - 3.9327 0.933 230117_WJC_METTL3_WT_vs_EV_F01.19174.19174.2 2.46 12-Aug R.WLLELSK[136.11].K sp|P35573|GDE_HUMAN 1 895.5259 0.68 5876 19174 2 895.521263 448.7702 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 6 3636 - 390424 - - - -5.1266 - 1.5 0.191 - 168.7 1 2 0 -0.0046 7 0 0 0 1.71E+07 2.50E+07 - - - 1.735 1 230117_WJC_METTL3_WT_vs_EV_F01.19176.19176.2 2.93E-05 24-Dec R.LDYLGVSYGLTPR.L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1452.7613 0.86 5878 19176 2 1452.764042 727.3879 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.83 3636.3 - 270070 - - - 1.9012 - 2.27 0.474 - 406.1 1 2 0 0.0028 13 0 0 0 2.73E+06 3.19E+06 - - - 4.6451 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.19181.19181.2 0.0301 14-Jul R.FYTIEILK.V sp|P12273|PIP_HUMAN 1 1025.5797 143.11 5881 19181 2 1025.582738 513.7971 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 6 3637 - 3.73E+06 - - - 2.9291 - 1.518 0.301 - 129.4 1 2 0 0.003 8 0 0 0 4.50E+08 3.15E+06 - - - 2.5221 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.19182.19182.3 0.0323 13/36 R.DFLLKPELLR.A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1242.7336 1.19 5882 19182 3 1242.736831 415.2518 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3637.1 - 2.33E+06 - - - 2.5927 - 2.319 0.338 - 223.2 1 2 0 0.0032 10 0 0 0 3.95E+07 3.33E+07 - - - 4.764 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19183.19183.2 0.0146 14-Oct K.LLQQLFLK[136.11].A sp|Q9P287|BCCIP_HUMAN 1 1009.6416 1.35 5883 19183 2 1009.644103 505.8281 BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1 8.75 3637.2 - 2.42E+06 - - - 2.5256 - 1.858 0.298 - 247.1 1 2 0 0.0026 8 0 0 0 2.41E+07 1.78E+07 - - - 3.1096 0.9719 230117_WJC_METTL3_WT_vs_EV_F01.19184.19184.2 0.995 16-Aug R.LLIDEAILK[136.11].C "sp|P49591|SYSC_HUMAN,tr|Q5T5C7|Q5T5C7_HUMAN" 2 1034.6467 1.74 5884 19184 2 1034.649339 518.3306 "Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3" 4.37 3637.2 - 948675 - - - 2.5526 - 1.131 0.082 - 134.4 1 2 0 0.0026 9 0 0 0 1.09E+07 6.27E+06 - - - 0.002 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19188.19188.2 9.43E-05 18-Sep K.GIFLGDDEWR[166.11].E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1216.5752 1.74 5888 19188 2 1216.579142 609.2949 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3637.7 - 605436 - - - 3.2345 - 1.901 0.493 - 252.3 1 2 0 0.0039 10 0 0 0 3.04E+07 1.75E+07 - - - 4.4741 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.19189.19189.2 0.0314 16-Aug K.YAFVNWINK.A "sp|P13797|PLST_HUMAN,sp|P13796|PLSL_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|Q5TBN3|Q5TBN3_HUMAN,tr|U3KQI3|U3KQI3_HUMAN" 5 1153.592 0.02 5889 19189 2 1153.593937 577.8033 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 8.59 3637.9 - 498366 - - - 1.6531 - 1.568 0.24 - 134.3 1 2 0 0.0019 9 0 0 0 2.87E+06 1.33E+08 - - - 2.1143 1 230117_WJC_METTL3_WT_vs_EV_F01.19190.19190.2 5.39E-09 26-Dec R.FIAVGYVDDTQFVR.F "sp|P04439|HLAA_HUMAN,tr|A0A140T953|A0A140T953_HUMAN,tr|A0A140T941|A0A140T941_HUMAN,tr|A0A1W2PQS8|A0A1W2PQS8_HUMAN,tr|A0A0G2JI36|A0A0G2JI36_HUMAN,tr|A0A140T8W8|A0A140T8W8_HUMAN,tr|Q9GJ45|Q9GJ45_HUMAN,tr|Q53Z42|Q53Z42_HUMAN,tr|Q5RJ27|Q5RJ27_HUMAN,tr|Q53YP1|Q53YP1_HUMAN,tr|Q5SRN5|Q5SRN5_HUMAN,tr|A0A1W2PS24|A0A1W2PS24_HUMAN,tr|A0A0G2JIF2|A0A0G2JIF2_HUMAN,tr|A0A1W2PQD0|A0A1W2PQD0_HUMAN,tr|A0A1W2PRZ0|A0A1W2PRZ0_HUMAN,tr|A0A140T9U0|A0A140T9U0_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A0G2JPD3|A0A0G2JPD3_HUMAN,tr|A0A140T9W2|A0A140T9W2_HUMAN,tr|O78179|O78179_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|A0A1W2PPQ2|A0A1W2PPQ2_HUMAN,tr|A0A140T9T1|A0A140T9T1_HUMAN,tr|Q5SPM2|Q5SPM2_HUMAN,tr|Q5SUL5|Q5SUL5_HUMAN,tr|A0A140T8Y4|A0A140T8Y4_HUMAN,tr|A0A140T975|A0A140T975_HUMAN,tr|A0A140TA03|A0A140TA03_HUMAN,tr|A0A140TA13|A0A140TA13_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A1W2PSE7|A0A1W2PSE7_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|A0A1W2PPF8|A0A1W2PPF8_HUMAN,tr|D9J307|D9J307_HUMAN,tr|A0A140T937|A0A140T937_HUMAN,tr|Q5SRN7|Q5SRN7_HUMAN,tr|A0A1W2PR61|A0A1W2PR61_HUMAN,tr|A0A140T912|A0A140T912_HUMAN,tr|A0A140T9M0|A0A140T9M0_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN,tr|A0A1W2PS39|A0A1W2PS39_HUMAN,tr|A0A140T9Z6|A0A140T9Z6_HUMAN,tr|A0A140T9M5|A0A140T9M5_HUMAN,tr|A0A140T930|A0A140T930_HUMAN,tr|A0A140T9Z4|A0A140T9Z4_HUMAN,tr|B0UXQ0|B0UXQ0_HUMAN,tr|A0A0G2JL56|A0A0G2JL56_HUMAN" 48 1628.8199 3.66 5890 19190 2 1628.824624 815.4172 "HLA class I histocompatibility antigen, A alpha chain OS=Homo sapiens OX=9606 GN=HLA-A PE=1 SV=2" 4.21 3638 - 389483 - - - 2.926 - 2.771 0.665 - 479.9 1 2 0 0.0048 14 0 0 0 4.75E+06 1.30E+06 - - - 6.5088 0.9923 230117_WJC_METTL3_WT_vs_EV_F01.19191.19191.2 0.00178 24-Jul R.LLPPEDTQELIFK.D sp|O60287|NPA1P_HUMAN 1 1541.8341 0.89 5891 19191 2 1541.844205 771.9243 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 4.14 3638.1 - 229941 - - - 6.5467 - 1.663 0.442 - 97.7 1 2 0 0.0101 13 0 0 0 1.41E+06 1.59E+06 - - - 3.6078 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19194.19194.2 0.000508 18-Nov K.C[160.03]LEEFELLGK[136.11].A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1244.6202 1.02 5893 19194 2 1244.61998 623.3174 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3638.5 - 1.72E+06 - - - -0.1968 - 1.916 0.435 - 351.5 1 2 0 -0.0002 10 0 0 0 9.93E+06 9.75E+06 - - - 4.0688 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19196.19196.2 0.0115 14-Sep K.LLQQLFLK.A sp|Q9P287|BCCIP_HUMAN 1 1001.6274 1.35 5894 19196 2 1001.6287 501.821 BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1 8.75 3638.7 - 2.94E+06 - - - 1.3448 - 1.784 0.3 - 195.7 1 2 0 0.0013 8 0 0 0 2.41E+07 1.78E+07 - - - 3.0022 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19197.19197.2 0.00803 16-Sep K.ASSLISLLK.Q "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 930.575 3.6 5895 19197 2 930.576785 466.2948 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.8 3638.8 - 1.03E+06 - - - 1.9364 - 1.913 0.403 - 289 1 2 0 0.0018 9 0 0 0 4.58E+07 1.27E+07 - - - 3.8936 1 230117_WJC_METTL3_WT_vs_EV_F01.19198.19198.2 4.27E-06 18-Oct K.GIFLGDDEWR.E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1206.5669 1.76 5896 19198 2 1206.569874 604.2907 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3638.9 - 1.20E+06 - - - 2.4342 - 2.283 0.481 - 335.5 1 2 0 0.0029 10 0 0 0 3.11E+07 1.76E+07 - - - 4.8969 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.19199.19199.2 0.0317 16-Aug K.VQWGVFVPR.D sp|Q8IWA0|WDR75_HUMAN 1 1086.5974 1.43 5897 19199 2 1086.599021 544.306 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 9.72 3638.9 - 830157 - - - 1.4458 - 1.509 0.255 - 241 1 2 0 0.0016 9 0 0 0 1.98E+07 1.38E+07 - - - 2.1143 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19200.19200.2 0.00522 20-Oct K.LLSAVDILGEK.F sp|Q14191|WRN_HUMAN 1 1156.6703 0.84 5898 19200 2 1156.672615 579.3424 Werner syndrome ATP-dependent helicase OS=Homo sapiens OX=9606 GN=WRN PE=1 SV=2 4.37 3639.1 - 735634 - - - 1.9669 - 2.198 0.354 - 183.9 1 2 0 0.0023 11 0 0 0 5.42E+06 6.48E+06 - - - 3.7854 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.19201.19201.2 0.0114 14-Jul R.LSFAVPFR.E sp|P78527|PRKDC_HUMAN 1 935.5229 1.16 5899 19201 2 935.522247 468.7687 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3639.1 - 726281 - - - -0.6852 - 1.831 0.279 - 147.2 1 2 0 -0.0006 8 0 0 0 3.35E+07 2.89E+07 - - - 2.9257 0.9945 230117_WJC_METTL3_WT_vs_EV_F01.19203.19203.2 0.00779 22-Aug K.TPLPPELADVQA.- "sp|Q9Y5V0|ZN706_HUMAN,tr|H0YC70|H0YC70_HUMAN" 2 1249.6554 - 5901 19203 2 1249.659712 625.835 Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1 3.67 3639.4 - 581798 - - - 3.4361 - 1.635 0.171 - 196.4 1 2 0 0.0043 12 0 0 0 - - - - - 1.5963 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.19204.19204.2 0.00465 14-Aug K.LGTLFAFK[136.11].K sp|Q6F5E8|CARL2_HUMAN 1 903.5309 6.04 5902 19204 2 903.535066 452.7727 "Capping protein, Arp2\3 and myosin-I linker protein 2 OS=Homo sapiens OX=9606 GN=CARMIL2 PE=1 SV=2" 8.75 3639.5 - 429318 - - - 4.5665 - 1.741 0.264 - 132.9 2 2 0 0.0041 8 0 0 0 2.92E+07 4.83E+06 - - - 2.5274 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.19205.19205.2 0.00558 16-Oct K.FALNSLLQR[166.11].Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1070.6112 2.26 5903 19205 2 1070.610335 536.3129 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.75 3639.6 - 413790 - - - -0.807 - 1.721 0.422 - 319.4 1 2 0 -0.0009 9 0 0 0 6.03E+07 2.67E+07 - - - 3.7283 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19207.19207.2 1.74E-05 24-Sep R.LLPPEDTQELIFK[136.11].D sp|O60287|NPA1P_HUMAN 1 1549.8483 0.85 5905 19207 2 1549.850589 775.9314 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 4.14 3639.8 - 196741 - - - 1.4698 - 1.972 0.461 - 174.1 1 2 0 0.0023 13 0 0 0 1.35E+06 1.59E+06 - - - 4.188 0.9959 230117_WJC_METTL3_WT_vs_EV_F01.19211.19211.2 0.221 12-Jun R.EYLYFLK.H sp|Q8N1N4|K2C78_HUMAN 1 974.5113 27.85 5908 19211 2 974.51445 488.2629 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 6.1 3640.3 - 5.24E+06 - - - 3.2119 - 1.248 0.271 - 141.9 1 2 0 0.0031 7 0 0 0 3.50E+07 1.26E+06 - - - 1.7436 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.19212.19212.2 0.00166 14-Oct R.LSFAVPFR[166.11].E sp|P78527|PRKDC_HUMAN 1 945.5312 1.16 5909 19212 2 945.533927 473.7729 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3640.4 - 1.93E+06 - - - 2.9285 - 1.972 0.342 - 346.3 1 2 0 0.0028 8 0 0 0 3.35E+07 2.89E+07 - - - 3.6141 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19213.19213.2 0.000185 16-Sep K.VQWGVFVPR[166.11].D sp|Q8IWA0|WDR75_HUMAN 1 1096.6057 1.59 5910 19213 2 1096.607788 549.3101 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 9.72 3640.5 - 1.21E+06 - - - 1.8858 - 1.864 0.428 - 404.4 1 2 0 0.0021 9 0 0 0 1.89E+07 1.19E+07 - - - 4.0031 0.9774 230117_WJC_METTL3_WT_vs_EV_F01.19216.19216.2 0.000114 16-Nov K.IIDGLLVMR[166.11].K "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1038.6135 3.19 5913 19216 2 1038.621725 520.314 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.84 3640.9 - 645630 - - - 7.9125 - 2.131 0.249 - 317.1 1 2 0 0.0082 9 0 0 0 1.72E+08 5.39E+07 - - - 3.0664 1 230117_WJC_METTL3_WT_vs_EV_F01.19227.19227.2 3.00E-07 16-Oct K.VFDAIMNFK.K sp|P13639|EF2_HUMAN 1 1083.5423 3.95 5922 19227 2 1083.544265 542.7784 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.81 3642.4 - 2.95E+06 - - - 1.8107 - 1.935 0.585 - 298.5 1 2 0 0.002 9 0 0 0 1.27E+08 3.22E+07 - - - 5.2709 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19230.19230.2 6.99E-06 16-Sep K.MC[160.03]LFAGFQR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1128.5209 0.84 5925 19230 2 1128.522544 565.2677 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3642.6 - 491674 - - - 1.4958 - 1.977 0.344 - 298.8 1 2 0 0.0017 9 0 0 0 9.67E+07 1.15E+08 - - - 3.5531 0.9947 230117_WJC_METTL3_WT_vs_EV_F01.19232.19232.2 0.432 14-Jun R.IPLNDLFR.C sp|P13473|LAMP2_HUMAN 1 986.5549 6.91 5927 19232 2 986.558792 494.2847 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3642.8 - 176626 - - - 3.9288 - 1.5 0.226 - 120.1 1 2 0 0.0039 8 0 0 0 1.21E+08 1.75E+07 - - - 1.9319 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19235.19235.2 0.000534 18-Sep R.LMALLGQALK[136.11].W sp|Q2TAY7|SMU1_HUMAN 1 1064.6507 1.07 5928 19235 2 1064.65243 533.3326 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.75 3643.2 - 2.29E+06 - - - 1.5902 - 1.79 0.334 - 288 1 2 0 0.0017 10 0 0 0 5.56E+07 5.20E+07 - - - 3.1325 1 230117_WJC_METTL3_WT_vs_EV_F01.19236.19236.2 9.70E-06 18-Oct K.TIC[160.03]AEFAILR.M "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1192.6274 1.3 5929 19236 2 1192.630111 597.321 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.66 3643.2 - 1.92E+06 - - - 2.2488 - 1.942 0.51 - 323.8 1 2 0 0.0027 10 0 0 0 2.66E+07 2.04E+07 - - - 4.6597 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19238.19238.3 0.00978 Sep-36 R.LFDQAFGLPR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1162.6135 0.8 5931 19238 3 1162.613204 388.5451 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3643.4 - 399006 - - - -0.2494 - 1.586 0.371 - 94.6 1 2 0 -0.0003 10 0 0 0 3.68E+06 4.59E+06 - - - 4.0232 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.19243.19243.2 0.0039 18-Sep R.DFLLKPELLR.A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1242.7336 2.02 5934 19243 2 1242.734684 622.3741 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3644.1 - 892499 - - - 0.865 - 1.835 0.285 - 317.6 1 2 0 0.0011 10 0 0 0 1.12E+07 5.53E+06 - - - 2.8401 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.19244.19244.2 0.000114 20-Oct K.ILVSLIEVAQK.L sp|Q9BSL1|UBAC1_HUMAN 1 1211.7489 3.31 5935 19244 2 1211.754067 606.8817 Ubiquitin-associated domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBAC1 PE=1 SV=1 6 3644.2 - 573713 - - - 4.2435 - 2.029 0.435 - 198.3 1 2 0 0.0051 11 0 0 0 3.97E+06 1.20E+06 - - - 4.1664 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.19245.19245.2 0.0267 16-Aug K.SGILPILVK[136.11].C sp|O00505|IMA4_HUMAN 1 946.6307 1.36 5936 19245 2 946.631906 474.3226 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3644.3 - 2.90E+06 - - - 1.3226 - 1.33 0.349 - 132.3 1 2 0 0.0013 9 0 0 0 5.78E+07 4.26E+07 - - - 2.4434 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19246.19246.2 0.000851 16-Oct K.VFDAIMNFK[136.11].K sp|P13639|EF2_HUMAN 1 1091.5565 3.94 5937 19246 2 1091.557505 546.7855 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.81 3644.4 - 2.71E+06 - - - 0.918 - 1.756 0.377 - 217 1 2 0 0.001 9 0 0 0 1.27E+08 3.22E+07 - - - 3.4541 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19249.19249.2 0.193 16-Sep K.GLSLGFLEK.K sp|Q9NU22|MDN1_HUMAN 1 962.5437 0.49 5940 19249 2 962.544993 482.2791 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6 3644.7 - 629230 - - - 1.361 - 1.741 0.269 - 180.3 1 2 0 0.0013 9 0 0 0 1.27E+07 2.58E+07 - - - 2.6315 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.19250.19250.2 0.000931 18-Aug R.DFLLK[136.11]PELLR[166.11].A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1260.7561 2.15 5941 19250 2 1260.756601 631.3853 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3644.9 - 497923 - - - 0.414 - 1.606 0.371 - 231.6 1 2 0 0.0005 10 0 0 0 1.19E+07 5.53E+06 - - - 3.1034 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19252.19252.2 0.000687 22-Nov K.GALPLDTVTFYK.V sp|P30040|ERP29_HUMAN 1 1323.7075 1.39 5943 19252 2 1323.709257 662.861 Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4 5.83 3645.1 - 365052 - - - 1.3621 - 2.148 0.405 - 314.7 1 2 0 0.0018 12 0 0 0 8.74E+06 6.28E+06 - - - 4.0434 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.19256.19256.2 0.00427 18-Sep R.LEPVIMELER[166.11].Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1237.6616 0.56 5946 19256 2 1237.663833 619.8381 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3645.6 - 8.14E+06 - - - 1.8204 - 1.632 0.333 - 322.3 1 2 0 0.0023 10 0 0 0 6.65E+07 1.20E+08 - - - 2.867 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19258.19258.2 8.39E-06 16-Nov K.SGILPILVK.C sp|O00505|IMA4_HUMAN 1 938.6165 1.36 5947 19258 2 938.617788 470.3155 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3645.9 - 8.66E+06 - - - 1.4212 - 2.18 0.439 - 283.7 1 2 0 0.0013 9 0 0 0 5.78E+07 4.25E+07 - - - 4.5377 0.9793 230117_WJC_METTL3_WT_vs_EV_F01.19259.19259.2 0.154 16-Nov S.GDLLSEVER.N "sp|O14513|NCKP5_HUMAN,tr|A0A0A0MSE4|A0A0A0MSE4_HUMAN,tr|A0A0A0MS79|A0A0A0MS79_HUMAN" 3 1016.5138 9.29 5948 19259 2 1016.515378 509.2642 Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=2 4.14 3645.9 - 4.40E+06 - - - 1.514 - 2.323 0.401 - 529.1 1 1 0 0.0015 9 0 0 0 1.05E+08 1.13E+07 - - - 4.4407 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.19260.19260.2 1.09 14-Aug R.VLLLPLER.D sp|O95071|UBR5_HUMAN 1 951.6117 2 5949 19260 2 951.613461 476.8131 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3646.1 - 1.36E+06 - - - 1.8474 - 1.65 0.113 - 217 1 2 0 0.0018 8 0 0 0 3.05E+07 1.53E+07 - - - 1.3854 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19262.19262.2 8.61E-07 22-Dec K.GALPLDTVTFYK[136.11].V sp|P30040|ERP29_HUMAN 1 1331.7217 1.39 5951 19262 2 1331.723981 666.8681 Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4 5.83 3646.3 - 981415 - - - 1.7474 - 2.326 0.197 - 498.4 1 2 0 0.0023 12 0 0 0 8.74E+06 6.28E+06 - - - 2.7164 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19264.19264.3 0.00756 Sep-36 R.LFDQAFGLPR[166.11].L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1172.6218 0.8 5953 19264 3 1172.624543 391.8812 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3646.6 - 823184 - - - 2.3699 - 1.354 0.366 - 79 1 2 0 0.0028 10 0 0 0 3.68E+06 4.59E+06 - - - 3.5048 0.9973 230117_WJC_METTL3_WT_vs_EV_F01.19266.19266.2 0.375 14-Aug K.LDFNWVTR.W "sp|Q86W92|LIPB1_HUMAN,tr|F5GZP6|F5GZP6_HUMAN" 2 1049.5294 1.35 5955 19266 2 1049.530144 525.772 Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2 5.84 3646.9 - 445605 - - - 0.6803 - 1.381 0.208 - 143.4 1 2 0 0.0007 8 0 0 0 4.85E+06 3.60E+06 - - - 1.5506 0.9691 230117_WJC_METTL3_WT_vs_EV_F01.19267.19267.3 0.155 Jul-36 K.SAEFLLHMLK[136.11].N "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 1195.6515 0.8 5956 19267 3 1195.652087 399.5578 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 6.47 3647 - 398262 - - - 0.5194 - 1.29 0.139 - 43.9 1 2 0 0.0006 10 0 0 0 2.32E+06 2.92E+06 - - - 0.8332 0.9941 230117_WJC_METTL3_WT_vs_EV_F01.19269.19269.3 0.0394 Jul-36 K.FLPFSFEHIR[166.11].E "sp|Q93050|VPP1_HUMAN,tr|F5H1T6|F5H1T6_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 4 1301.6796 1.34 5958 19269 3 1301.679597 434.9005 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 6.75 3647.2 - 286278 - - - -0.0123 - 1.424 0.225 - 49.3 1 2 0 0 10 0 0 0 3.65E+06 2.73E+06 - - - 2.0808 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.19272.19272.2 7.21E-05 16-Oct K.MC[160.03]LFAGFQR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1138.5291 0.84 5960 19272 2 1138.533235 570.2718 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3647.6 - 2.15E+07 - - - 3.609 - 1.959 0.34 - 603.1 1 2 0 0.0041 9 0 0 0 9.65E+07 1.15E+08 - - - 3.4963 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.19274.19274.2 0.000231 18-Sep K.SVPDEIILLR.S sp|Q9H9A6|LRC40_HUMAN 1 1153.6707 2.62 5961 19274 2 1153.675776 577.8426 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.37 3647.8 - 2.63E+06 - - - 4.4224 - 1.785 0.454 - 381.3 1 2 0 0.0051 10 0 0 0 3.11E+07 1.19E+07 - - - 4.01 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.19276.19276.2 0.0105 18-Sep R.NIQGLFAPLK.L "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1099.639 0.27 5963 19276 2 1099.64103 550.8268 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 8.75 3647.9 - 954087 - - - 1.8642 - 1.444 0.303 - 193.1 1 2 0 0.0021 10 0 0 0 6.14E+06 2.27E+07 - - - 2.3039 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19278.19278.2 0.000534 13/24 R.ALGLGLVSPAQLR.V "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|A8MRA7|A8MRA7_HUMAN" 3 1293.7769 2.83 5965 19278 2 1293.779361 647.8957 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 9.79 3648.1 - 834160 - - - 1.9246 - 2.742 0.228 - 729.4 1 2 0 0.0025 13 0 0 0 8.15E+06 2.88E+06 - - - 3.3131 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19281.19281.2 0.0287 14-Aug K.MIDLIIPR[166.11].G sp|P54886|P5CS_HUMAN 1 979.5764 1.46 5968 19281 2 979.578341 490.7955 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 5.59 3648.5 - 698979 - - - 1.9886 - 1.726 0.314 - 182.8 3 2 0 0.0019 8 0 0 0 1.17E+07 8.00E+06 - - - 2.7926 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.19284.19284.3 0.00846 Nov-40 R.FPFLGVHFTPR.M "sp|Q9H9P8|L2HDH_HUMAN,tr|C9JVN9|C9JVN9_HUMAN" 2 1316.703 11.08 5971 19284 3 1316.705044 439.9083 "L-2-hydroxyglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=L2HGDH PE=1 SV=3" 9.76 3648.9 - 264706 - - - 1.5698 - 2.414 0.179 - 94.8 1 2 0 0.0021 11 0 0 0 2.74E+06 2.47E+05 - - - 3.0387 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.19285.19285.3 0.0147 Oct-36 K.FLPFSFEHIR.E "sp|Q93050|VPP1_HUMAN,tr|F5H1T6|F5H1T6_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 4 1291.6713 1.34 5972 19285 3 1291.673049 431.5644 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 6.75 3649 - 263414 - - - 1.3208 - 1.49 0.289 - 110.1 1 2 0 0.0017 10 0 0 0 3.65E+06 2.73E+06 - - - 2.9262 1 230117_WJC_METTL3_WT_vs_EV_F01.19286.19286.2 4.34E-05 15/32 R.AAVEEGIVLGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1683.8978 4.05 5973 19286 2 1683.901832 842.9562 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3649.1 - 263091 - - - 2.3998 - 2.856 0.542 - 617.1 1 2 0 0.004 17 0 0 0 1.98E+06 4.88E+05 - - - 5.623 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19289.19289.2 0.00487 16-Oct K.IIDGLLVMR.K "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1028.6052 3.19 5974 19289 2 1028.607911 515.3099 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.84 3649.5 - 2.72E+06 - - - 2.5996 - 1.925 0.345 - 245.5 1 2 0 0.0027 9 0 0 0 1.72E+08 5.39E+07 - - - 3.4831 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.19291.19291.2 1.2 14-Jul R.VLLLPLER[166.11].D sp|O95071|UBR5_HUMAN 1 961.62 1.94 5976 19291 2 961.622692 481.8173 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3649.7 - 1.48E+06 - - - 2.8275 - 1.575 0.225 - 164.5 1 2 0 0.0027 8 0 0 0 3.05E+07 1.57E+07 - - - 2.072 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.19292.19292.2 0.0875 14-Jul K.MIDLIIPR.G sp|P54886|P5CS_HUMAN 1 969.5681 1.43 5977 19292 2 969.571131 485.7913 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 5.59 3649.8 - 1.23E+06 - - - 3.1024 - 1.589 0.211 - 197.2 3 2 0 0.003 8 0 0 0 1.17E+07 8.20E+06 - - - 1.7821 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.19293.19293.2 0.198 14-Jul R.IPLNDLFR[166.11].C sp|P13473|LAMP2_HUMAN 1 996.5632 6.64 5978 19293 2 996.566666 499.2889 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3649.8 - 1.17E+06 - - - 3.492 - 1.575 0.217 - 144.8 1 2 0 0.0035 8 0 0 0 1.23E+08 1.86E+07 - - - 2.0127 0.9969 230117_WJC_METTL3_WT_vs_EV_F01.19296.19296.2 0.00672 12-Aug R.IQLLVFK[136.11].H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 867.5673 0.67 5981 19296 2 867.569608 434.7909 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3650.2 - 349129 - - - 2.6315 - 1.722 0.123 - 187.4 1 2 0 0.0023 7 0 0 0 1.77E+07 2.65E+07 - - - 1.6708 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.19301.19301.2 0.00786 24-Aug K.FIAELGVPLSQVK.S sp|Q86T24|KAISO_HUMAN 1 1399.8075 7.3 5986 19301 2 1399.813044 700.911 Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2 6 3650.8 - 222627 - - - 3.9591 - 1.717 0.339 - 140.5 2 2 0 0.0055 13 0 0 0 3.48E+06 4.76E+05 - - - 2.7961 1 230117_WJC_METTL3_WT_vs_EV_F01.19302.19302.2 1.90E-05 24-Nov R.LLPGEEC[160.03]VLDGLR[166.11].V sp|O95248|MTMR5_HUMAN 1 1479.7631 1.32 5987 19302 2 1479.765975 740.8888 Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4 4.14 3651 - 207481 - - - 1.953 - 2.132 0.515 - 237.1 1 2 0 0.0029 13 0 0 0 2.49E+06 1.88E+06 - - - 4.7869 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.19304.19304.2 0.0337 20-Oct R.IGQLFFGVPPK.Q sp|Q7L5D6|GET4_HUMAN 1 1201.6859 0.41 5989 19304 2 1201.688175 601.8502 Golgi to ER traffic protein 4 homolog OS=Homo sapiens OX=9606 GN=GET4 PE=1 SV=1 8.75 3651.2 - 332319 - - - 1.8682 - 1.983 0.204 - 223.4 1 2 0 0.0022 11 0 0 0 1.06E+07 2.57E+07 - - - 2.3991 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.19308.19308.2 0.216 16-Sep R.LQLPVWEYK.D sp|O43143|DHX15_HUMAN 1 1174.6386 1.91 5992 19308 2 1174.641088 588.3266 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 3651.7 - 4.76E+06 - - - 2.0789 - 1.654 0.22 - 248.6 1 2 0 0.0024 9 0 0 0 9.65E+07 5.05E+07 - - - 2.1209 0.9879 230117_WJC_METTL3_WT_vs_EV_F01.19310.19310.2 0.118 12-Jul R.IQLLVFK.H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 859.5531 0.67 5994 19310 2 859.555959 430.7838 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3651.9 - 1.28E+06 - - - 3.2971 - 1.491 0.08 - 157.2 1 2 0 0.0028 7 0 0 0 1.77E+07 2.65E+07 - - - 0.8967 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.19311.19311.2 0.0111 20-Oct K.LIDFGSGALLK.D "sp|P11309|PIM1_HUMAN,sp|Q86V86|PIM3_HUMAN" 2 1132.6492 0.03 5995 19311 2 1132.654628 567.3319 Serine\threonine-protein kinase pim-1 OS=Homo sapiens OX=9606 GN=PIM1 PE=1 SV=4 5.84 3652 - 668032 - - - 4.7826 - 1.971 0.335 - 172.2 1 2 0 0.0054 11 0 0 0 1.96E+06 6.61E+07 - - - 3.3492 0.9899 230117_WJC_METTL3_WT_vs_EV_F01.19313.19313.2 0.382 12-Jul R.DYLQLLR[166.11].K sp|L0R6Q1|S35U4_HUMAN 1 929.521 1.58 5997 19313 2 929.523878 465.7678 SLC35A4 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=SLC35A4 PE=3 SV=1 5.84 3652.3 - 616726 - - - 3.1102 - 1.363 0.126 - 204 1 2 0 0.0029 7 0 0 0 6.38E+06 4.05E+06 - - - 0.952 1 230117_WJC_METTL3_WT_vs_EV_F01.19314.19314.2 0.000101 15/22 K.LSTIALALGVER[166.11].T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1251.7426 2.07 5998 19314 2 1251.747112 626.8786 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3652.4 - 506258 - - - 3.599 - 2.705 0.424 - 889.2 1 2 0 0.0045 12 0 0 0 2.81E+07 1.36E+07 - - - 4.7895 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19317.19317.2 0.0723 16-Oct R.NEVVGLIFR.L "sp|Q8NBU5|ATAD1_HUMAN,tr|A0A7P0TAM5|A0A7P0TAM5_HUMAN,tr|A0A7P0T9B4|A0A7P0T9B4_HUMAN,tr|A0A7P0Z4J1|A0A7P0Z4J1_HUMAN,tr|A0A7P0T7Z9|A0A7P0T7Z9_HUMAN,tr|A0A7P0T9U2|A0A7P0T9U2_HUMAN" 6 1045.592 0.98 6001 19317 2 1045.593724 523.8033 Outer mitochondrial transmembrane helix translocase OS=Homo sapiens OX=9606 GN=ATAD1 PE=1 SV=1 6 3652.8 - 324962 - - - 1.6201 - 1.766 0.325 - 320.6 1 2 0 0.0017 9 0 0 0 1.25E+06 1.27E+06 - - - 3.0862 0.9948 230117_WJC_METTL3_WT_vs_EV_F01.19318.19318.2 0.482 14-Jul K.GLLDVLPK.N "sp|O95071|UBR5_HUMAN,tr|E7ET84|E7ET84_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 853.5273 3.31 6002 19318 2 853.529875 427.7709 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.84 3652.9 - 304051 - - - 3.0122 - 1.429 0.178 - 128.3 1 2 0 0.0026 8 0 0 0 1.49E+06 4.50E+05 - - - 1.4315 0.999 230117_WJC_METTL3_WT_vs_EV_F01.19322.19322.2 0.0186 18-Oct R.LEPVIMELER.Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1227.6533 0.52 6005 19322 2 1227.657022 614.8339 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3653.4 - 1.18E+06 - - - 3.0237 - 1.869 0.31 - 287.7 1 2 0 0.0037 10 0 0 0 6.23E+07 1.19E+08 - - - 3.0752 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19324.19324.2 0.0122 14-Sep K.ILTPIIFK.E "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5L9|H7C5L9_HUMAN" 4 943.6106 0.75 6006 19324 2 943.613639 472.8126 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 8.75 3653.6 - 1.86E+06 - - - 3.1782 - 1.909 0.462 - 228.1 1 2 0 0.003 8 0 0 0 1.25E+07 1.66E+07 - - - 4.4024 1 230117_WJC_METTL3_WT_vs_EV_F01.19326.19326.2 1.66E-05 13/22 K.LSTIALALGVER.T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1241.7343 2.03 6008 19326 2 1241.737627 621.8744 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3653.7 - 2.38E+06 - - - 2.6495 - 2.568 0.449 - 699.6 1 2 0 0.0033 12 0 0 0 2.76E+07 1.36E+07 - - - 4.8378 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19327.19327.2 0.00459 16-Sep K.EAEILEVLR[166.11].H sp|P36551|HEM6_HUMAN 1 1080.6054 0.95 6009 19327 2 1080.605388 541.31 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.25 3653.8 - 1.44E+06 - - - -0.0527 - 2.007 0.293 - 229.9 1 2 0 -0.0001 9 0 0 0 9.86E+06 1.04E+07 - - - 3.2205 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19328.19328.2 0.00484 16-Sep K.LLIYWASTR.E sp|P06312|KV401_HUMAN 1 1121.6233 203.26 6010 19328 2 1121.624982 561.8189 Immunoglobulin kappa variable 4-1 OS=Homo sapiens OX=9606 GN=IGKV4-1 PE=1 SV=1 8.75 3653.9 - 1.24E+06 - - - 1.4729 - 1.987 0.355 - 282.5 1 2 0 0.0017 9 0 0 0 3.05E+07 1.50E+05 - - - 3.649 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19329.19329.2 0.0286 18-Sep R.AVLDALLEGK[136.11].A "sp|P46821|MAP1B_HUMAN,sp|P78559|MAP1A_HUMAN,tr|E9PGC8|E9PGC8_HUMAN" 3 1035.6056 3.13 6011 19329 2 1035.606163 518.8101 Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2 4.37 3653.9 - 1.15E+06 - - - 0.5813 - 1.946 0.302 - 262.8 1 2 0 0.0006 10 0 0 0 8.54E+07 2.73E+07 - - - 3.1298 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.19330.19330.2 0.0309 12-Jul R.DYLQLLR.K sp|L0R6Q1|S35U4_HUMAN 1 919.5127 1.59 6012 19330 2 919.515025 460.7636 SLC35A4 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=SLC35A4 PE=3 SV=1 5.84 3654 - 999596 - - - 2.51 - 1.257 0.246 - 254.4 1 2 0 0.0023 7 0 0 0 6.38E+06 4.01E+06 - - - 1.582 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.19331.19331.2 0.122 14-Sep K.GLLQLQWK[136.11].Q sp|O94826|TOM70_HUMAN 1 992.5899 1.46 6013 19331 2 992.592166 497.3022 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.75 3654.1 - 965742 - - - 2.3313 - 1.79 0.227 - 238.5 1 2 0 0.0023 8 0 0 0 7.13E+06 4.88E+06 - - - 2.4728 0.9238 230117_WJC_METTL3_WT_vs_EV_F01.19334.19334.2 4.44 16-Jun R.ESLTGPPYL.- "sp|Q9BRA0|LSMD1_HUMAN,tr|I3L4V0|I3L4V0_HUMAN,tr|I3L310|I3L310_HUMAN,tr|I3L3Z2|I3L3Z2_HUMAN,tr|A0A0B4J297|A0A0B4J297_HUMAN" 5 975.4913 - 6016 19334 2 975.494911 488.7529 "N-alpha-acetyltransferase 38, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA38 PE=1 SV=1" 4 3654.4 - 551587 - - - 3.6884 - 1.163 0.077 - 57.2 4 2 0 0.0036 9 0 0 0 - - - - - -0.2235 1 230117_WJC_METTL3_WT_vs_EV_F01.19335.19335.2 1.30E-06 20-Nov R.FSTIEEFSYIR[166.11].R "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1400.6852 1.21 6017 19335 2 1400.68852 701.3499 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 4.53 3654.5 - 520095 - - - 2.4045 - 2.259 0.506 - 408.6 1 2 0 0.0034 11 0 0 0 3.04E+06 2.51E+06 - - - 4.9818 0.9939 230117_WJC_METTL3_WT_vs_EV_F01.19336.19336.2 0.623 20-Jul K.ELFPIQMEGVK[136.11].L "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 1297.6832 1.09 6018 19336 2 1297.685725 649.8489 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.53 3654.7 - 463934 - - - 1.9766 - 1.397 0.129 - 120.1 1 2 0 0.0026 11 0 0 0 5.76E+06 5.31E+06 - - - 0.8974 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.19337.19337.2 0.00417 12-Jul K.FFFDPVR[166.11].K "sp|Q9NRZ9|HELLS_HUMAN,tr|A0A087WSW7|A0A087WSW7_HUMAN,tr|B1ALG6|B1ALG6_HUMAN,tr|A0A0B4J1V9|A0A0B4J1V9_HUMAN,tr|F6XU50|F6XU50_HUMAN" 5 936.4733 1.14 6019 19337 2 936.475607 469.2439 Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1 5.84 3654.8 - 435156 - - - 2.455 - 1.303 0.37 - 115.4 1 2 0 0.0023 7 0 0 0 4.88E+06 4.27E+06 - - - 2.6117 0.9721 230117_WJC_METTL3_WT_vs_EV_F01.19338.19338.2 0.000293 24-Aug R.SYEAVAAAAASVY.N sp|Q9BWF3|RBM4_HUMAN 1 1271.6034 - 6020 19338 2 1271.604409 636.809 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4 3654.9 - 427246 - - - 0.8069 - 1.708 0.467 - 173.9 1 1 0 0.001 13 0 0 0 - - - - - 3.8639 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19339.19339.2 0.000146 20-Nov K.ELFPIQMEGVK.L "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 1289.669 1.07 6021 19339 2 1289.672508 645.8418 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.53 3655.1 - 421693 - - - 2.7511 - 1.969 0.36 - 356.7 1 2 0 0.0035 11 0 0 0 5.76E+06 5.36E+06 - - - 3.5317 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19341.19341.2 0.113 20-Nov K.GPILMELQTYR.Y "sp|P08559|ODPA_HUMAN,sp|P29803|ODPAT_HUMAN" 2 1319.6908 3.56 6023 19341 2 1319.695061 660.8527 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 6 3655.3 - 350561 - - - 3.2606 - 2.244 0.437 - 463.9 1 2 0 0.0043 11 0 0 0 3.41E+06 9.57E+05 - - - 4.4539 0.9933 230117_WJC_METTL3_WT_vs_EV_F01.19342.19342.2 0.0323 20-Sep K.LLEVQILEVQR.A "sp|Q8IWJ2|GCC2_HUMAN,tr|H7BYJ9|H7BYJ9_HUMAN" 2 1338.7871 1.29 6024 19342 2 1338.794138 670.4008 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.53 3655.5 - 323555 - - - 5.2563 - 1.733 0.283 - 296.2 1 2 0 0.007 11 0 0 0 3.27E+06 2.54E+06 - - - 2.6165 1 230117_WJC_METTL3_WT_vs_EV_F01.19347.19347.2 0.00019 18-Oct R.IIVAIDGWPR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1148.6581 3.02 6028 19347 2 1148.664398 575.3364 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3656 - 3.94E+06 - - - 5.4403 - 2.279 0.471 - 351.3 1 2 0 0.0062 10 0 0 0 7.28E+07 2.41E+07 - - - 4.8171 0.9612 230117_WJC_METTL3_WT_vs_EV_F01.19348.19348.2 0.116 14-Jul K.GLLQLQWK.Q sp|O94826|TOM70_HUMAN 1 984.5757 1.48 6029 19348 2 984.581428 493.2951 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.75 3656 - 2.09E+06 - - - 5.8665 - 1.374 0.18 - 131.8 1 2 0 0.0058 8 0 0 0 7.23E+06 4.88E+06 - - - 1.3269 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.19351.19351.2 5.69E-05 18-Dec K.SVVTSIFGVK[136.11].N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1043.6106 1.9 6032 19351 2 1043.616241 522.8126 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3656.3 - 1.38E+06 - - - 5.3602 - 2.285 0.435 - 382 1 2 0 0.0056 10 0 0 0 2.50E+07 1.31E+07 - - - 4.5588 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.19353.19353.2 0.00102 18-Oct K.LYSVVSQLIR[166.11].C "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 1186.6949 1.16 6034 19353 2 1186.701325 594.3547 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3656.6 - 1.27E+06 - - - 5.3898 - 1.87 0.392 - 374.6 1 2 0 0.0064 10 0 0 0 4.69E+06 4.05E+06 - - - 3.6815 0.9954 230117_WJC_METTL3_WT_vs_EV_F01.19356.19356.2 0.235 14-Oct K.LAIVLFTK.E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 903.5793 1.98 6037 19356 2 903.583653 452.7969 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3657 - 615352 - - - 4.7732 - 2.032 0.201 - 269.7 1 2 0 0.0043 8 0 0 0 3.08E+06 1.55E+06 - - - 2.6626 0.9959 230117_WJC_METTL3_WT_vs_EV_F01.19358.19358.2 0.00232 18-Sep R.LFLTMEINPK.V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 1204.6526 12.3 6039 19358 2 1204.65955 603.3336 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3657.2 - 402529 - - - 5.7851 - 2.06 0.379 - 250.3 1 2 0 0.007 10 0 0 0 3.50E+06 2.85E+05 - - - 3.8554 0.9774 230117_WJC_METTL3_WT_vs_EV_F01.19359.19359.2 0.908 14-Jul K.LAIVLFTK[136.11].E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 911.5935 1.98 6040 19359 2 911.597405 456.804 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3657.4 - 356582 - - - 4.2398 - 1.659 0.063 - 111.2 2 2 0 0.0039 8 0 0 0 3.08E+06 1.55E+06 - - - 0.8974 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.19360.19360.3 0.126 13/44 K.LSTIALALGVER.T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1241.7343 1.6 6041 19360 3 1241.74001 414.9187 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3657.5 - 339641 - - - 4.5686 - 2.253 0.296 - 140.1 1 2 0 0.0057 12 0 0 0 1.43E+06 8.92E+05 - - - 4.09 0.9482 230117_WJC_METTL3_WT_vs_EV_F01.19361.19361.2 1.8 12-Jun R.IIIWNLR[166.11].S sp|Q14149|MORC3_HUMAN 1 936.5784 3.54 6042 19361 2 936.583175 469.2965 MORC family CW-type zinc finger protein 3 OS=Homo sapiens OX=9606 GN=MORC3 PE=1 SV=3 9.75 3657.6 - 226111 - - - 5.0535 - 1.338 0.097 - 82 1 2 0 0.0047 7 0 0 0 3.07E+06 8.66E+05 - - - 0.6786 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19367.19367.2 0.00235 16-Sep K.VFSIGPVFR[166.11].A sp|P14868|SYDC_HUMAN 1 1030.5839 1.06 6046 19367 2 1030.585284 516.2992 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3658.3 - 5.35E+06 - - - 1.3216 - 1.67 0.327 - 318.6 1 2 0 0.0014 9 0 0 0 2.99E+07 2.81E+07 - - - 2.9394 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.19369.19369.2 0.000452 16-Oct K.VFSIGPVFR.A sp|P14868|SYDC_HUMAN 1 1020.5757 1.06 6048 19369 2 1020.580511 511.2951 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3658.5 - 4.88E+06 - - - 4.761 - 1.783 0.394 - 394 1 2 0 0.0049 9 0 0 0 2.99E+07 2.81E+07 - - - 3.6226 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.19370.19370.2 0.000363 16-Oct R.QINWTVLYR.R "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1191.64 0.94 6049 19370 2 1191.645957 596.8273 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 8.75 3658.6 - 1.39E+06 - - - 4.9629 - 2.253 0.412 - 614.5 1 2 0 0.0059 9 0 0 0 2.89E+07 3.08E+07 - - - 4.4321 0.9855 230117_WJC_METTL3_WT_vs_EV_F01.19371.19371.2 0.0957 14-Aug R.SIFDYALR.S "sp|Q99570|PI3R4_HUMAN,tr|D6RBB7|D6RBB7_HUMAN,tr|D6RJ98|D6RJ98_HUMAN,tr|D6RAC3|D6RAC3_HUMAN" 4 983.5076 2.16 6050 19371 2 983.512565 492.7611 Phosphoinositide 3-kinase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PIK3R4 PE=1 SV=3 5.55 3658.8 - 870898 - - - 5.0157 - 1.218 0.278 - 149.5 1 2 0 0.0049 8 0 0 0 2.60E+06 1.21E+06 - - - 1.6875 0.997 230117_WJC_METTL3_WT_vs_EV_F01.19372.19372.2 0.00617 18-Aug K.LLVLSALAEK.L sp|Q13395|TARB1_HUMAN 1 1055.659 1.62 6051 19372 2 1055.663665 528.8368 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6 3658.9 - 1.02E+06 - - - 4.3745 - 1.596 0.338 - 126.8 1 2 0 0.0046 10 0 0 0 3.08E+06 1.90E+06 - - - 2.841 0.999 230117_WJC_METTL3_WT_vs_EV_F01.19374.19374.2 0.00315 20-Dec R.GVIFTEAFVAR.H sp|O94874|UFL1_HUMAN 1 1208.6554 2.35 6053 19374 2 1208.660235 605.335 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 6 3659.2 - 479388 - - - 4.0342 - 2.459 0.382 - 335.7 1 2 0 0.0049 11 0 0 0 6.52E+06 2.78E+06 - - - 4.295 0.9836 230117_WJC_METTL3_WT_vs_EV_F01.19375.19375.2 1.3 12-Jun R.IIIWNLR.S sp|Q14149|MORC3_HUMAN 1 926.5702 0.39 6054 19375 2 926.572748 464.2924 MORC family CW-type zinc finger protein 3 OS=Homo sapiens OX=9606 GN=MORC3 PE=1 SV=3 9.75 3659.3 - 446914 - - - 2.7801 - 1.261 0.092 - 84.4 1 2 0 0.0026 7 0 0 0 4.37E+06 1.13E+07 - - - 0.4545 0.9881 230117_WJC_METTL3_WT_vs_EV_F01.19377.19377.2 0.0886 12-Aug R.LDFLPLK.C "sp|Q8WV99|ZFN2B_HUMAN,tr|F8WEE4|F8WEE4_HUMAN,tr|E9PFU9|E9PFU9_HUMAN,tr|C9J1R6|C9J1R6_HUMAN,tr|B4DEN4|B4DEN4_HUMAN,tr|A0A087X0D9|A0A087X0D9_HUMAN,tr|B8ZZ56|B8ZZ56_HUMAN,tr|E7EV05|E7EV05_HUMAN" 8 844.5058 0.84 6056 19377 2 844.511217 423.2602 AN1-type zinc finger protein 2B OS=Homo sapiens OX=9606 GN=ZFAND2B PE=1 SV=1 5.84 3659.5 - 330351 - - - 6.3659 - 1.907 0.235 - 202.3 1 2 0 0.0054 7 0 0 0 4.12E+06 4.91E+06 - - - 2.8204 1 230117_WJC_METTL3_WT_vs_EV_F01.19378.19378.2 1.61E-05 14/24 R.IPSPLGYAAIPIK[136.11].F sp|Q9Y3A4|RRP7A_HUMAN 1 1346.8053 1.58 6057 19378 2 1346.808123 674.4099 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 8.59 3659.7 - 307786 - - - 2.0783 - 2.06 0.548 - 290.1 1 2 0 0.0028 13 0 0 0 3.88E+07 2.45E+07 - - - 4.9425 0.9155 230117_WJC_METTL3_WT_vs_EV_F01.19379.19379.2 0.77 14-Aug R.SIFDYALR[166.11].S "sp|Q99570|PI3R4_HUMAN,tr|D6RBB7|D6RBB7_HUMAN,tr|D6RJ98|D6RJ98_HUMAN,tr|D6RAC3|D6RAC3_HUMAN" 4 993.5159 3.08 6058 19379 2 993.523382 497.7652 Phosphoinositide 3-kinase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PIK3R4 PE=1 SV=3 5.55 3659.8 - 420312 - - - 7.5288 - 1.259 0.236 - 141.6 1 2 0 0.0075 8 0 0 0 2.54E+06 8.25E+05 - - - 1.4764 1 230117_WJC_METTL3_WT_vs_EV_F01.19383.19383.2 6.45E-07 13/22 R.LC[160.03]LTDEEVVFVR[166.11].L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1488.7522 -1 6062 19383 2 1488.753007 745.3834 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3660.3 - 156169 - - - 0.5515 - 2.652 0.56 - 750.2 1 2 0 0.0008 12 0 0 0 0.00E+00 0.00E+00 - - - 5.7431 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19388.19388.2 0.000552 18-Aug R.LWIANYSLPR[166.11].A sp|O43172|PRP4_HUMAN 1 1241.6796 3.22 6065 19388 2 1241.681343 621.8471 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3661 - 3.84E+06 - - - 1.3933 - 2.064 0.267 - 204.7 1 2 0 0.0017 10 0 0 0 7.08E+07 2.20E+07 - - - 3.0352 1 230117_WJC_METTL3_WT_vs_EV_F01.19390.19390.2 3.09E-07 16-Oct K.MDLVTYFGK.R sp|P09543|CN37_HUMAN 1 1072.5263 4.43 6067 19390 2 1072.529417 537.2704 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 5.59 3661.2 - 1.90E+06 - - - 2.8894 - 2.237 0.524 - 487.4 1 2 0 0.0031 9 0 0 0 9.91E+06 2.24E+06 - - - 5.2396 1 230117_WJC_METTL3_WT_vs_EV_F01.19391.19391.2 4.57E-06 18-Oct K.ELPEYYELIR.K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1323.6711 1.63 6068 19391 2 1323.674042 662.8428 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3661.4 - 1.39E+06 - - - 2.2468 - 2.121 0.501 - 391.8 1 2 0 0.003 10 0 0 0 1.01E+07 6.21E+06 - - - 4.8392 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.19392.19392.2 0.000318 16-Sep R.LSYPTFFPR.F "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1126.5811 1.91 6069 19392 2 1126.57892 564.2978 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 8.75 3661.5 - 1.23E+06 - - - -1.9626 - 1.661 0.435 - 213 1 2 0 -0.0022 9 0 0 0 1.07E+07 5.59E+06 - - - 3.7212 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19393.19393.2 0.00133 16-Oct K.ISVNDFIIK[136.11].A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1055.6106 0.73 6070 19393 2 1055.613817 528.8126 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 3661.6 - 1.12E+06 - - - 3.003 - 1.955 0.39 - 191.9 1 2 0 0.0032 9 0 0 0 6.08E+06 8.38E+06 - - - 3.86 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.19394.19394.2 0.016 12-Aug K.QFLDYFK.T "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 959.4753 1.41 6071 19394 2 959.477374 480.7449 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.83 3661.7 - 804454 - - - 2.1939 - 1.478 0.253 - 231.7 1 2 0 0.0021 7 0 0 0 6.24E+06 4.44E+06 - - - 2.1469 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19395.19395.2 5.38E-05 18-Oct K.ELPEYYELIR[166.11].K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1333.6793 1.63 6072 19395 2 1333.682064 667.8469 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3661.9 - 799502 - - - 2.044 - 1.94 0.448 - 403.5 1 2 0 0.0027 10 0 0 0 1.01E+07 6.21E+06 - - - 4.1988 1 230117_WJC_METTL3_WT_vs_EV_F01.19396.19396.2 0.000253 17/26 K.VLELDPALAPVVSR.E "sp|O00170|AIP_HUMAN,tr|A0A804HKK3|A0A804HKK3_HUMAN,tr|A0A804HKL7|A0A804HKL7_HUMAN,tr|A0A804HJ46|A0A804HJ46_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN" 6 1477.8504 5.17 6073 19396 2 1477.853437 739.9325 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 4.37 3662 - 732793 - - - 2.0347 - 2.985 0.526 - 743.4 1 2 0 0.003 14 0 0 0 1.05E+07 2.04E+06 - - - 5.6694 1 230117_WJC_METTL3_WT_vs_EV_F01.19397.19397.2 2.32E-06 14/22 R.VVYSAFLMATPR.L sp|Q15029|U5S1_HUMAN 1 1353.7115 1.34 6074 19397 2 1353.714765 677.863 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.72 3662.1 - 694122 - - - 2.4171 - 2.722 0.521 - 750.5 1 2 0 0.0033 12 0 0 0 6.80E+06 5.06E+06 - - - 5.5228 0.9875 230117_WJC_METTL3_WT_vs_EV_F01.19398.19398.2 0.117 12-Jul K.QFLDYFK[136.11].T "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 967.4895 1.26 6075 19398 2 967.492328 484.752 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.83 3662.2 - 548151 - - - 2.9551 - 1.184 0.155 - 147.6 1 2 0 0.0029 7 0 0 0 6.55E+06 5.18E+06 - - - 0.7201 0.997 230117_WJC_METTL3_WT_vs_EV_F01.19400.19400.2 0.619 12-Jun R.YVLNFLR.T "sp|Q8NC69|KCTD6_HUMAN,tr|F5H7I0|F5H7I0_HUMAN" 2 923.5229 2.43 6077 19400 2 923.52503 462.7687 BTB\POZ domain-containing protein KCTD6 OS=Homo sapiens OX=9606 GN=KCTD6 PE=1 SV=2 8.75 3662.5 - 389716 - - - 2.3194 - 1.262 0.243 - 125.2 1 2 0 0.0021 7 0 0 0 1.75E+06 7.21E+05 - - - 1.5724 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19402.19402.2 0.00668 22-Dec K.VLGTEELYGYLK[136.11].K "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1391.7428 1.14 6079 19402 2 1391.745985 696.8787 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.53 3662.8 - 347062 - - - 2.3007 - 2.223 0.434 - 322 1 2 0 0.0032 12 0 0 0 6.75E+06 5.92E+06 - - - 4.3474 1 230117_WJC_METTL3_WT_vs_EV_F01.19404.19404.2 4.78E-07 15/24 V.ALVMLQEDELLSK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1495.8047 1.47 6081 19404 2 1495.80665 748.9096 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3663 - 286267 - - - 1.2823 - 2.864 0.401 - 667.1 1 1 0 0.0019 13 0 0 0 1.73E+07 1.18E+07 - - - 4.7027 1 230117_WJC_METTL3_WT_vs_EV_F01.19406.19406.2 0.000308 13/20 K.MALDIEIAAYR[166.11].K "sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,sp|P12036|NFH_HUMAN,sp|P07196|NFL_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 6 1274.6568 1.29 6083 19406 2 1274.660962 638.3357 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.37 3663.3 - 260434 - - - 3.2424 - 2.795 0.504 - 865.1 1 2 0 0.0041 11 0 0 0 5.30E+06 4.11E+06 - - - 5.5428 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19411.19411.2 0.00188 22-Sep R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.19 6087 19411 2 1323.803338 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3663.8 - 6.87E+06 - - - 2.0887 - 1.806 0.4 - 213.8 1 2 0 0.0028 12 0 0 0 1.96E+09 1.65E+09 - - - 3.5499 1 230117_WJC_METTL3_WT_vs_EV_F01.19412.19412.2 4.77E-06 14/22 R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.19 6088 19412 2 1315.789755 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3663.9 - 6.29E+06 - - - 2.5703 - 2.508 0.584 - 569.1 1 2 0 0.0034 12 0 0 0 1.96E+09 1.65E+09 - - - 5.7727 1 230117_WJC_METTL3_WT_vs_EV_F01.19413.19413.2 3.78E-06 14/24 V.ALVMLQEDELLSK.M sp|Q96A49|SYAP1_HUMAN 1 1487.7905 1.47 6089 19413 2 1487.794449 744.9025 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3663.9 - 6.26E+06 - - - 2.6328 - 2.875 0.505 - 718.6 1 1 0 0.0039 13 0 0 0 1.73E+07 1.18E+07 - - - 5.4801 1 230117_WJC_METTL3_WT_vs_EV_F01.19414.19414.2 2.96E-07 22-Dec K.VLGTEELYGYLK.K "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1383.7286 1.14 6090 19414 2 1383.731734 692.8716 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.53 3664 - 2.82E+06 - - - 2.2772 - 2.377 0.502 - 385.8 1 2 0 0.0032 12 0 0 0 6.75E+06 5.92E+06 - - - 5.026 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19415.19415.2 0.00447 16-Aug R.YVALTSLLK.T sp|O43747|AP1G1_HUMAN 1 1006.6063 1.48 6091 19415 2 1006.609363 504.3104 AP-1 complex subunit gamma-1 OS=Homo sapiens OX=9606 GN=AP1G1 PE=1 SV=5 8.59 3664 - 2.47E+06 - - - 3.0598 - 1.71 0.533 - 132.6 1 2 0 0.0031 9 0 0 0 4.58E+06 3.09E+06 - - - 4.5289 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.19416.19416.2 0.678 16-Sep R.VLEALLPLK.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 994.6427 1.77 6092 19416 2 994.645825 498.3286 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3664.1 - 2.22E+06 - - - 3.173 - 1.836 0.279 - 261.3 1 2 0 0.0032 9 0 0 0 7.30E+07 4.13E+07 - - - 2.8585 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.19419.19419.2 0.0806 14-Aug K.FITIFGTR.S "sp|P08758|ANXA5_HUMAN,tr|D6RBL5|D6RBL5_HUMAN,tr|D6RBE9|D6RBE9_HUMAN" 3 953.5335 0.72 6095 19419 2 953.536083 477.774 Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5 PE=1 SV=2 9.75 3664.5 - 1.03E+06 - - - 2.7592 - 1.72 0.176 - 186.1 1 2 0 0.0026 8 0 0 0 3.20E+06 4.44E+06 - - - 1.9757 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.19420.19420.2 0.0329 14-Jun K.GLLDVLPK[136.11].N "sp|O95071|UBR5_HUMAN,tr|E7ET84|E7ET84_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 861.5415 2.54 6096 19420 2 861.54279 431.778 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.84 3664.6 - 907176 - - - 1.4927 - 1.271 0.364 - 79.5 1 2 0 0.0013 8 0 0 0 6.54E+06 2.57E+06 - - - 2.4523 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19421.19421.2 6.10E-05 18-Aug R.FMEPYIFGSR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 1255.5935 1.34 6097 19421 2 1255.597256 628.804 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 6 3664.7 - 879690 - - - 2.9914 - 1.797 0.518 - 248.3 1 2 0 0.0038 10 0 0 0 3.59E+06 2.68E+06 - - - 4.5018 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.19425.19425.2 0.68 12-Jun R.LWAELLR[166.11].T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN" 3 909.5312 1.84 6101 19425 2 909.532999 455.7729 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 6 3665.2 - 399339 - - - 2.0241 - 1.346 0.153 - 102.8 1 2 0 0.0018 7 0 0 0 4.05E+06 2.20E+06 - - - 1.112 1 230117_WJC_METTL3_WT_vs_EV_F01.19432.19432.2 1.71E-07 18-Nov R.LWIANYSLPR.A sp|O43172|PRP4_HUMAN 1 1231.6713 3.16 6107 19432 2 1231.677431 616.8429 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3666.1 - 3.60E+06 - - - 4.9429 - 2.394 0.548 - 611.9 1 2 0 0.0061 10 0 0 0 7.12E+07 2.26E+07 - - - 5.5233 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19433.19433.2 0.0743 16-Nov R.VLEALLPLK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1002.6569 1.77 6108 19433 2 1002.660405 502.3357 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3666.2 - 3.02E+06 - - - 3.5266 - 2.029 0.399 - 396.3 1 2 0 0.0035 9 0 0 0 7.30E+07 4.13E+07 - - - 4.0339 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.19435.19435.2 0.0075 18-Nov K.TFTLSATLLR[166.11].H sp|Q9UEG4|ZN629_HUMAN 1 1131.6527 0.26 6110 19435 2 1131.651784 566.8336 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.41 3666.3 - 1.60E+06 - - - -0.8351 - 1.909 0.162 - 384.4 1 2 0 -0.0009 10 0 0 0 2.21E+06 8.55E+06 - - - 2.042 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.19437.19437.2 0.0707 16-Oct K.GVILLIVDK.A "sp|P78344|IF4G2_HUMAN,tr|H0YE44|H0YE44_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 8 968.627 2.04 6112 19437 2 968.630791 485.3208 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.84 3666.6 - 1.23E+06 - - - 3.8952 - 1.89 0.18 - 288.1 1 2 0 0.0038 9 0 0 0 7.48E+06 3.66E+06 - - - 2.2109 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19439.19439.2 0.000616 16-Oct K.IFAFDLDAK[136.11].R sp|Q96P11|NSUN5_HUMAN 1 1046.5528 0.82 6114 19439 2 1046.556726 524.2837 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 4.21 3666.8 - 1.21E+06 - - - 3.7542 - 1.938 0.459 - 231.1 1 2 0 0.0039 9 0 0 0 6.56E+06 7.96E+06 - - - 4.3441 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.19441.19441.2 0.696 14-Sep R.QWELLLEK.M "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SFF6|A0A0D9SFF6_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN,tr|A0A5F9ZHC3|A0A5F9ZHC3_HUMAN" 5 1057.5808 0.66 6116 19441 2 1057.58394 529.7977 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 3667 - 1.08E+06 - - - 2.9719 - 1.66 0.254 - 287.4 1 2 0 0.0031 8 0 0 0 7.02E+06 1.07E+07 - - - 2.4446 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.19443.19443.2 0.000387 16-Jul R.LSYPTFFPR[166.11].F "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1136.5894 2.42 6118 19443 2 1136.594423 569.302 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 8.75 3667.3 - 889320 - - - 4.4185 - 1.543 0.382 - 116.8 1 2 0 0.005 9 0 0 0 1.64E+07 6.76E+06 - - - 3.1157 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19444.19444.2 0.00115 16/24 K.LGLSLVVPGGGIK.K sp|Q99747|SNAG_HUMAN 1 1208.7493 2.62 6119 19444 2 1208.753398 605.3819 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3667.4 - 799224 - - - 3.4242 - 2.765 0.292 - 621 1 2 0 0.0041 13 0 0 0 6.16E+06 2.35E+06 - - - 3.8067 1 230117_WJC_METTL3_WT_vs_EV_F01.19445.19445.3 7.21E-07 19/56 K.LLQVASPFLEPHLVR.M "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1717.9879 4.18 6120 19445 3 1717.996275 573.6699 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 6.75 3667.5 - 702417 - - - 4.8598 - 3.546 0.566 - 431.9 1 2 0 0.0083 15 0 0 0 4.26E+06 1.02E+06 - - - 8.151 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.19446.19446.2 0.0276 12-Jul K.FGFIGFK[136.11].S sp|Q9Y4C8|RBM19_HUMAN 1 822.452 0.97 6121 19446 2 822.452909 412.2333 Probable RNA-binding protein 19 OS=Homo sapiens OX=9606 GN=RBM19 PE=1 SV=3 8.75 3667.7 - 662160 - - - 1.1527 - 1.518 0.285 - 116.8 1 2 0 0.0009 7 0 0 0 2.15E+06 2.21E+06 - - - 2.4682 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.19447.19447.3 0.000565 13/44 R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.16 6122 19447 3 1323.804203 442.2741 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3667.8 - 619858 - - - 2.7421 - 2.379 0.398 - 223.5 1 2 0 0.0036 12 0 0 0 3.49E+07 3.02E+07 - - - 5.3786 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19448.19448.2 0.334 14/24 K.LGLSLVVPGGGIK[136.11].K sp|Q99747|SNAG_HUMAN 1 1216.7635 2.62 6123 19448 2 1216.767031 609.389 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3667.9 - 342303 - - - 2.9357 - 2.345 0.362 - 407.6 1 2 0 0.0036 13 0 0 0 6.16E+06 2.35E+06 - - - 3.901 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.19449.19449.2 0.00653 16-Aug R.TFLHTVC[160.03]FY.- sp|Q9NP77|SSU72_HUMAN 1 1186.5481 - 6124 19449 2 1186.551273 594.2813 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 OS=Homo sapiens OX=9606 GN=SSU72 PE=1 SV=1 6.4 3668.1 - 304130 - - - 2.6598 - 1.351 0.346 - 138.9 1 2 0 0.0032 9 0 0 0 - - - - - 2.4659 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.19451.19451.2 0.169 12-Jul R.LWAELLR.T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN" 3 899.5229 1.8 6125 19451 2 899.525044 450.7687 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 6 3668.3 - 648512 - - - 2.3968 - 1.523 0.184 - 196.2 1 2 0 0.0022 7 0 0 0 4.03E+06 2.23E+06 - - - 1.7323 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.19453.19453.3 0.00193 Nov-44 R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.05 6127 19453 3 1315.787627 439.6027 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3668.5 - 2.49E+06 - - - 0.953 - 2.026 0.475 - 142.6 1 2 0 0.0013 12 0 0 0 3.53E+07 3.36E+07 - - - 5.7925 1 230117_WJC_METTL3_WT_vs_EV_F01.19454.19454.2 4.44E-09 20-Dec R.FFDEESYSLLR.K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1404.6561 1.65 6128 19454 2 1404.656764 703.3353 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3668.5 - 2.01E+06 - - - 0.44 - 2.483 0.587 - 328.7 1 2 0 0.0006 11 0 0 0 1.25E+08 7.56E+07 - - - 5.8367 1 230117_WJC_METTL3_WT_vs_EV_F01.19455.19455.2 2.08E-10 13/20 R.FFDEESYSLLR[166.11].K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1414.6644 1.65 6129 19455 2 1414.665583 708.3395 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3668.6 - 1.78E+06 - - - 0.8249 - 2.566 0.514 - 413.9 1 2 0 0.0012 11 0 0 0 1.25E+08 7.56E+07 - - - 5.3863 1 230117_WJC_METTL3_WT_vs_EV_F01.19456.19456.2 0.0022 14/24 R.IITLTGPTNAIFK[136.11].A sp|Q15365|PCBP1_HUMAN 1 1395.8217 3.59 6130 19456 2 1395.822991 698.9181 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3668.7 - 1.69E+06 - - - 0.9235 - 2.616 0.459 - 479.6 1 2 0 0.0013 13 0 0 0 2.34E+08 6.52E+07 - - - 4.8989 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.19458.19458.2 0.0167 14-Jun R.ILPWSTFR.L "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1018.56 1.19 6132 19458 2 1018.562298 510.2873 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3668.9 - 1.15E+06 - - - 2.2542 - 1.231 0.318 - 123.2 1 2 0 0.0023 8 0 0 0 2.07E+07 1.75E+07 - - - 2.0158 1 230117_WJC_METTL3_WT_vs_EV_F01.19459.19459.2 0.000205 14/22 K.ATGILLYGLASR.L "sp|P47897|SYQ_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|F2Z2V6|F2Z2V6_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 9 1233.7081 0.86 6133 19459 2 1233.711287 617.8613 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 8.79 3669 - 1.05E+06 - - - 2.5654 - 2.669 0.412 - 680.3 1 2 0 0.0032 12 0 0 0 4.77E+06 5.56E+06 - - - 4.6661 0.9338 230117_WJC_METTL3_WT_vs_EV_F01.19462.19462.2 7.15 14-May K.KDDFDWGK.Y "sp|Q96RT8|GCP5_HUMAN,tr|A0A0G2JPW5|A0A0G2JPW5_HUMAN,tr|A0A0G2JSA7|A0A0G2JSA7_HUMAN,tr|A0A0G2JQX1|A0A0G2JQX1_HUMAN,tr|A0A0G2JQK2|A0A0G2JQK2_HUMAN,tr|A0A087X1Z1|A0A087X1Z1_HUMAN,tr|A0A087WVZ8|A0A087WVZ8_HUMAN,tr|A0A0G2JS51|A0A0G2JS51_HUMAN,tr|A0A087WVL9|A0A087WVL9_HUMAN" 9 1009.4505 11.5 6136 19462 2 1009.451799 505.7325 Gamma-tubulin complex component 5 OS=Homo sapiens OX=9606 GN=TUBGCP5 PE=1 SV=1 4.43 3669.3 - 711913 - - - 1.2759 - 0.735 0.15 - 73.1 1 2 0 0.0013 8 0 0 0 1.43E+07 1.24E+06 - - - -0.7801 1 230117_WJC_METTL3_WT_vs_EV_F01.19470.19470.2 0.000609 18-Dec R.LGLDDFESLK[136.11].V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1143.5903 0.44 6142 19470 2 1143.59026 572.8024 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3670.3 - 4.69E+06 - - - -0.0393 - 2.566 0.507 - 342.2 1 2 0 0 10 0 0 0 6.57E+07 1.50E+08 - - - 5.4161 0.93 230117_WJC_METTL3_WT_vs_EV_F01.19472.19472.2 0.0215 14-Jun K.NALESYAF.N "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 913.4181 - 6144 19472 2 913.418683 457.7164 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4 3670.5 - 2.97E+06 - - - 0.5857 - 1.243 0.391 - 125.7 1 1 0 0.0005 8 0 0 0 - - - - - 2.5848 1 230117_WJC_METTL3_WT_vs_EV_F01.19473.19473.2 4.57E-06 16-Dec K.LPFPIIDDR[166.11].N sp|P30041|PRDX6_HUMAN 1 1094.6 1.28 6145 19473 2 1094.600682 548.3073 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.21 3670.6 - 1.72E+06 - - - 0.6541 - 2.331 0.514 - 670.7 1 2 0 0.0007 9 0 0 0 1.65E+08 1.28E+08 - - - 5.2856 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19474.19474.2 0.00234 18-Oct R.LGLDDFESLK.V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1135.5761 0.44 6146 19474 2 1135.577346 568.7953 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3670.7 - 1.59E+06 - - - 1.0928 - 2.121 0.454 - 202.5 1 2 0 0.0012 10 0 0 0 6.57E+07 1.50E+08 - - - 4.4926 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19478.19478.2 0.00018 18-Oct R.VIEQLLVGLK.D "sp|Q9BTW9|TBCD_HUMAN,tr|A0A804HJ32|A0A804HJ32_HUMAN,tr|A0A804HKT8|A0A804HKT8_HUMAN,tr|A0A804HHW7|A0A804HHW7_HUMAN,tr|A0A804HL21|A0A804HL21_HUMAN,tr|A0A804HKB9|A0A804HKB9_HUMAN,tr|A0A804HJY5|A0A804HJY5_HUMAN,tr|A0A804HI02|A0A804HI02_HUMAN,tr|A0A804HIU1|A0A804HIU1_HUMAN,tr|A0A804HJ57|A0A804HJ57_HUMAN,tr|A0A804HLF8|A0A804HLF8_HUMAN,tr|A0A804HL62|A0A804HL62_HUMAN,tr|A0A804HIC0|A0A804HIC0_HUMAN,tr|J3KR97|J3KR97_HUMAN,tr|A0A804HI57|A0A804HI57_HUMAN,tr|A0A804HIN6|A0A804HIN6_HUMAN,tr|A0A804HLI2|A0A804HLI2_HUMAN" 17 1110.7012 1.45 6150 19478 2 1110.703803 556.3579 Tubulin-specific chaperone D OS=Homo sapiens OX=9606 GN=TBCD PE=1 SV=2 5.97 3671.2 - 545098 - - - 2.3021 - 2.18 0.386 - 199.2 1 2 0 0.0026 10 0 0 0 3.26E+06 2.24E+06 - - - 4.0665 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.19479.19479.2 0.00028 13/22 R.NIPGITLLNVSK[136.11].L "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1275.7642 0.88 6151 19479 2 1275.77053 638.8894 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.75 3671.3 - 216791 - - - 4.9719 - 2.144 0.475 - 395.7 1 2 0 0.0063 12 0 0 0 1.96E+06 2.23E+06 - - - 4.5541 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19481.19481.2 3.60E-05 22-Oct R.EALLAEMGVAVR.E sp|O43896|KIF1C_HUMAN 1 1257.6751 0.41 6153 19481 2 1257.675938 629.8448 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 4.53 3671.6 - 149246 - - - 0.6599 - 2.096 0.325 - 348.6 1 2 0 0.0008 12 0 0 0 8.75E+05 2.14E+06 - - - 3.3883 0.8642 230117_WJC_METTL3_WT_vs_EV_F01.19485.19485.2 0.113 14-Jul R.WALGQVFR.Q "sp|P26572|MGAT1_HUMAN,tr|D6RF69|D6RF69_HUMAN" 2 975.529 1.16 6156 19485 2 976.534001 488.7718 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 9.75 3672.1 - 1.48E+06 - - - 1030.1744 - 1.44 0.277 - 122.6 1 2 0 1.005 8 0 0 0 1.97E+07 1.70E+07 - - - 1.8711 0.9885 230117_WJC_METTL3_WT_vs_EV_F01.19487.19487.2 0.551 16-Aug K.LSPEELLLR.W "sp|P13797|PLST_HUMAN,sp|Q14651|PLSI_HUMAN,sp|P13796|PLSL_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|C9JAM8|C9JAM8_HUMAN" 5 1068.6179 3 6158 19487 2 1068.61792 535.3162 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.53 3672.3 - 1.56E+06 - - - 0.0094 - 1.338 0.103 - 92.3 1 2 0 0 9 0 0 0 2.05E+07 6.82E+06 - - - 0.6441 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.19488.19488.2 0.00771 18-Aug R.FLVPIESIER[166.11].A sp|Q14249|NUCG_HUMAN 1 1211.6789 4.12 6159 19488 2 1211.677961 606.8467 "Endonuclease G, mitochondrial OS=Homo sapiens OX=9606 GN=ENDOG PE=1 SV=4" 4.53 3672.4 - 766381 - - - -0.8113 - 1.833 0.41 - 201.8 1 2 0 -0.001 10 0 0 0 2.41E+07 5.86E+06 - - - 3.7604 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.19497.19497.2 0.0016 14-Jun K.LVYVDLLR.E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 989.591 1.96 6166 19497 2 989.593974 495.8028 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.84 3673.6 - 226752 - - - 3.0386 - 1.403 0.379 - 145.6 1 2 0 0.003 8 0 0 0 4.55E+07 2.32E+07 - - - 2.8606 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.19499.19499.2 0.00581 14-Aug R.WALGQVFR[166.11].Q "sp|P26572|MGAT1_HUMAN,tr|D6RF69|D6RF69_HUMAN" 2 985.5373 1.1 6168 19499 2 985.536579 493.7759 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 9.75 3673.7 - 725903 - - - -0.7377 - 1.747 0.39 - 307.8 1 2 0 -0.0007 8 0 0 0 1.86E+07 1.69E+07 - - - 3.6039 1 230117_WJC_METTL3_WT_vs_EV_F01.19502.19502.2 4.03E-05 14/24 R.TPFTTAQLLALER.K sp|P28360|MSX1_HUMAN 1 1459.8035 1.81 6171 19502 2 1459.803811 730.909 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3674 - 0 - - - 0.2274 - 2.714 0.529 - 622.4 1 2 0 0.0003 13 0 0 0 1.56E+07 8.62E+06 - - - 5.5106 0.999 230117_WJC_METTL3_WT_vs_EV_F01.19505.19505.2 0.0017 14-Aug K.LVYVDLLR[166.11].E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 999.5992 1.98 6172 19505 2 999.598422 500.8069 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.84 3674.4 - 2.90E+06 - - - -0.8153 - 1.622 0.398 - 235.6 1 2 0 -0.0008 8 0 0 0 4.55E+07 2.30E+07 - - - 3.4391 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19507.19507.2 0.00195 20-Oct R.LLGLGVTDFSR[166.11].A "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 1186.6585 0.67 6173 19507 2 1186.661503 594.3365 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 5.84 3674.6 - 884177 - - - 2.4944 - 2.091 0.426 - 287.2 1 2 0 0.003 11 0 0 0 9.14E+06 1.36E+07 - - - 4.182 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.19509.19509.2 0.0254 22-Sep R.GILLFGPPGTGK.S "sp|Q9UN37|VPS4A_HUMAN,sp|O75351|VPS4B_HUMAN,sp|Q6PIW4|FIGL1_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 4 1155.6652 4.96 6175 19509 2 1155.671081 578.8399 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 8.75 3674.7 - 413115 - - - 5.0932 - 1.894 0.303 - 175 1 2 0 0.0059 12 0 0 0 1.10E+07 2.22E+06 - - - 2.9576 1 230117_WJC_METTL3_WT_vs_EV_F01.19510.19510.2 7.54E-06 14/24 R.TPFTTAQLLALER[166.11].K sp|P28360|MSX1_HUMAN 1 1469.8117 1.81 6176 19510 2 1469.812687 735.9132 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3674.9 - 371451 - - - 0.6382 - 2.935 0.547 - 672.9 1 2 0 0.0009 13 0 0 0 1.56E+07 8.62E+06 - - - 5.8442 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19512.19512.2 0.051 18-Sep R.LLLQIPSTIR[166.11].S sp|Q16394|EXT1_HUMAN 1 1162.7313 0.78 6178 19512 2 1162.732831 582.3729 Exostosin-1 OS=Homo sapiens OX=9606 GN=EXT1 PE=1 SV=2 9.75 3675.1 - 201370 - - - 1.3047 - 1.771 0.264 - 219.8 1 2 0 0.0015 10 0 0 0 2.79E+06 3.58E+06 - - - 2.5858 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.19515.19515.2 0.306 14-Jun K.GVLSDLTK.V "sp|Q8NG11|TSN14_HUMAN,tr|A6NEP9|A6NEP9_HUMAN,tr|H7BXY6|H7BXY6_HUMAN" 3 831.4702 5.82 6179 19515 2 831.471016 416.7424 Tetraspanin-14 OS=Homo sapiens OX=9606 GN=TSPAN14 PE=1 SV=1 5.84 3675.5 - 375364 - - - 1.0018 - 1.339 0.189 - 115 1 2 0 0.0008 8 0 0 0 1.23E+07 2.12E+06 - - - 1.3171 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19521.19521.2 0.0459 18-Oct K.LFLELEPQVR[166.11].D "sp|Q13098|CSN1_HUMAN,tr|A0A096LP07|A0A096LP07_HUMAN,tr|A8K070|A8K070_HUMAN,tr|C9JFE4|C9JFE4_HUMAN,tr|A0A096LPJ3|A0A096LPJ3_HUMAN" 5 1252.7055 1.24 6183 19521 2 1252.707605 627.36 COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4 4.53 3676.2 - 1.06E+06 - - - 1.686 - 2.098 0.285 - 390.8 1 2 0 0.0021 10 0 0 0 8.88E+06 7.15E+06 - - - 3.2137 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.19522.19522.2 0.00201 16-Aug K.DVDLEFLAK[136.11].M "sp|P55072|TERA_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN" 6 1056.5583 0.73 6184 19522 2 1056.561376 529.2864 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.03 3676.3 - 2.25E+06 - - - 2.9331 - 1.573 0.253 - 146.5 1 2 0 0.0031 9 0 0 0 1.23E+07 1.69E+07 - - - 2.2192 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19524.19524.2 2.24 22-Oct K.LILSLEGGYNLR[166.11].A "sp|Q9UBN7|HDAC6_HUMAN,tr|A0A2R8YCS4|A0A2R8YCS4_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 3 1356.7641 0.63 6186 19524 2 1356.766174 679.3893 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 6 3676.5 - 1.02E+06 - - - 1.55 - 2.139 0.305 - 269.2 1 2 0 0.0021 12 0 0 0 3.49E+06 5.51E+06 - - - 3.2936 0.997 230117_WJC_METTL3_WT_vs_EV_F01.19528.19528.2 0.0629 22-Dec K.LILSLEGGYNLR.A "sp|Q9UBN7|HDAC6_HUMAN,tr|A0A2R8YCS4|A0A2R8YCS4_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 3 1346.7558 0.63 6190 19528 2 1346.751517 674.3852 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 6 3677.1 - 707830 - - - -3.181 - 2.409 0.396 - 509.3 1 2 0 -0.0043 12 0 0 0 3.49E+06 5.51E+06 - - - 4.2779 0.995 230117_WJC_METTL3_WT_vs_EV_F01.19529.19529.2 0.45 12-Jun K.LFGELFK[136.11].L "sp|Q15032|R3HD1_HUMAN,tr|A0A804HIA8|A0A804HIA8_HUMAN,tr|H7C207|H7C207_HUMAN" 3 860.4887 1.03 6191 19529 2 860.490136 431.2516 R3H domain-containing protein 1 OS=Homo sapiens OX=9606 GN=R3HDM1 PE=1 SV=3 6 3677.2 - 703657 - - - 1.6212 - 1.272 0.16 - 87.2 1 2 0 0.0014 7 0 0 0 6.43E+06 6.26E+06 - - - 0.9846 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.19531.19531.2 0.018 16-Sep R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 6.85 6193 19531 2 1006.574766 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3677.5 - 584723 - - - 4.8362 - 1.792 0.43 - 196.6 1 2 0 0.0049 9 0 0 0 4.05E+06 5.91E+05 - - - 3.9031 1 230117_WJC_METTL3_WT_vs_EV_F01.19532.19532.2 0.000515 13/24 R.ILDIDNVDLAMGK[136.11].M sp|O43615|TIM44_HUMAN 1 1423.7472 2.76 6194 19532 2 1423.748795 712.8809 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3677.6 - 582336 - - - 1.1083 - 2.585 0.463 - 512.1 1 2 0 0.0016 13 0 0 0 2.60E+07 9.43E+06 - - - 4.8977 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.19535.19535.3 0.0357 Dec-48 R.TPFTTAQLLALER[166.11].K sp|P28360|MSX1_HUMAN 1 1469.8117 2.21 6197 19535 3 1469.811169 490.9445 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3678 - 405645 - - - -0.3946 - 1.965 0.221 - 212.5 1 2 0 -0.0006 13 0 0 0 3.27E+06 1.48E+06 - - - 2.8352 1 230117_WJC_METTL3_WT_vs_EV_F01.19541.19541.2 9.00E-05 16-Dec K.TLEEILLER[166.11].A "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 3 1124.6317 2.02 6202 19541 2 1124.634683 563.3231 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.25 3678.6 - 3.59E+06 - - - 2.688 - 2.516 0.462 - 480.3 1 2 0 0.003 9 0 0 0 8.29E+07 4.10E+07 - - - 5.1217 1 230117_WJC_METTL3_WT_vs_EV_F01.19543.19543.2 3.44E-05 14/24 R.ILDIDNVDLAMGK.M sp|O43615|TIM44_HUMAN 1 1415.733 2.76 6204 19543 2 1415.736454 708.8738 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3678.7 - 2.05E+06 - - - 2.4277 - 2.717 0.589 - 600.8 1 2 0 0.0034 13 0 0 0 2.60E+07 9.43E+06 - - - 5.9556 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19545.19545.2 0.000297 16-Oct K.IPSVLFLGK.L sp|Q8IW75|SPA12_HUMAN 1 972.6008 49.63 6206 19545 2 972.60384 487.3077 Serpin A12 OS=Homo sapiens OX=9606 GN=SERPINA12 PE=1 SV=1 8.75 3679 - 1.32E+06 - - - 3.1215 - 2.097 0.451 - 251.1 1 2 0 0.003 9 0 0 0 1.00E+07 2.02E+05 - - - 4.5135 0.9918 230117_WJC_METTL3_WT_vs_EV_F01.19546.19546.2 0.0282 16-Jul K.LSPEELLLR[166.11].W "sp|P13797|PLST_HUMAN,sp|Q14651|PLSI_HUMAN,sp|P13796|PLSL_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|C9JAM8|C9JAM8_HUMAN" 5 1078.6262 2.61 6207 19546 2 1078.629534 540.3204 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.53 3679.1 - 1.31E+06 - - - 3.1095 - 1.611 0.093 - 136.6 1 2 0 0.0034 9 0 0 0 7.64E+07 2.93E+07 - - - 1.1064 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.19547.19547.2 0.0171 18-Oct K.SLLFVNTLER.S "sp|Q9NY93|DDX56_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1190.6659 0.71 6208 19547 2 1190.670357 596.3402 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 5.72 3679.2 - 648831 - - - 3.724 - 2.082 0.311 - 363.8 1 2 0 0.0044 10 0 0 0 1.67E+07 2.36E+07 - - - 3.3836 1 230117_WJC_METTL3_WT_vs_EV_F01.19548.19548.2 8.76E-07 13/22 K.YDAFLASESLIK[136.11].Q sp|P62906|RL10A_HUMAN 1 1363.7115 0.86 6209 19548 2 1363.716625 682.863 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.37 3679.3 - 566508 - - - 3.7706 - 2.684 0.566 - 565.5 1 2 0 0.0051 12 0 0 0 8.35E+07 9.74E+07 - - - 5.8176 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19550.19550.2 0.00874 20-Nov K.ILEAVTLVQLK[136.11].E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1233.7788 0.87 6211 19550 2 1233.78187 617.8967 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6 3679.6 - 531050 - - - 2.5086 - 2.321 0.385 - 254.6 1 2 0 0.0031 11 0 0 0 9.53E+06 1.10E+07 - - - 4.1614 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.19551.19551.2 5.75E-06 16-Aug R.WLVFDEADR[166.11].L "sp|Q9H8H2|DDX31_HUMAN,tr|F8WAJ0|F8WAJ0_HUMAN" 2 1159.5537 0.8 6212 19551 2 1159.557746 580.7841 Probable ATP-dependent RNA helicase DDX31 OS=Homo sapiens OX=9606 GN=DDX31 PE=1 SV=2 4.03 3679.7 - 457292 - - - 3.4513 - 1.969 0.436 - 163 1 2 0 0.004 9 0 0 0 2.78E+06 3.46E+06 - - - 4.2202 0.9916 230117_WJC_METTL3_WT_vs_EV_F01.19553.19553.2 2.15 14-Aug R.LPLFGLGR[166.11].L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 881.5362 1.31 6214 19553 2 881.53907 441.7754 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3680 - 365733 - - - 3.2069 - 1.488 0.122 - 232.4 1 2 0 0.0028 8 0 0 0 2.66E+08 2.03E+08 - - - 1.1398 1 230117_WJC_METTL3_WT_vs_EV_F01.19556.19556.2 1.80E-05 13/24 R.IITLAGPTNAIFK.A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1357.7969 2.63 6215 19556 2 1357.799791 679.9057 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3680.4 - 632305 - - - 2.1019 - 2.411 0.544 - 575 1 2 0 0.0029 13 0 0 0 7.20E+08 2.74E+08 - - - 5.3167 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.19559.19559.2 0.281 14-Aug R.LPLFGLGR.L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 871.528 1.31 6218 19559 2 871.528439 436.7713 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3680.7 - 395390 - - - 0.5347 - 1.48 0.144 - 194.4 1 2 0 0.0005 8 0 0 0 2.66E+08 2.03E+08 - - - 1.2868 1 230117_WJC_METTL3_WT_vs_EV_F01.19561.19561.2 2.85E-06 15/20 K.ILEAVTLVQLK.E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1225.7646 0.87 6220 19561 2 1225.766175 613.8896 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6 3681 - 204936 - - - 1.3053 - 2.96 0.421 - 545.3 1 2 0 0.0016 11 0 0 0 9.53E+06 1.10E+07 - - - 5.0857 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.19562.19562.2 0.0529 12-Jun R.SGMFWLR[166.11].F sp|P31930|QCR1_HUMAN 1 905.4457 1.04 6221 19562 2 905.447181 453.7301 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 9.47 3681.1 - 203828 - - - 1.6202 - 1.414 0.288 - 132.7 1 2 0 0.0015 7 0 0 0 7.86E+06 7.59E+06 - - - 2.2654 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.19568.19568.2 0.0149 16-Oct R.MADLSELLK.E "sp|P30519|HMOX2_HUMAN,tr|I3L276|I3L276_HUMAN,tr|I3L159|I3L159_HUMAN,tr|I3L463|I3L463_HUMAN,tr|I3L4P8|I3L4P8_HUMAN,tr|A0A1B0GXH0|A0A1B0GXH0_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 8 1018.5369 0.69 6225 19568 2 1018.535506 510.2757 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 4.37 3681.9 - 1.39E+06 - - - -1.3519 - 2.051 0.271 - 328.2 1 2 0 -0.0014 9 0 0 0 1.03E+07 1.49E+07 - - - 3.1203 0.999 230117_WJC_METTL3_WT_vs_EV_F01.19569.19569.2 0.00322 18-Oct R.LTC[160.03]LGVWLDK[136.11].V sp|Q9NWT1|PK1IP_HUMAN 1 1211.6464 0.97 6226 19569 2 1211.649295 606.8305 p21-activated protein kinase-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAK1IP1 PE=1 SV=2 5.83 3682 - 920843 - - - 2.405 - 1.933 0.241 - 275.7 1 2 0 0.0029 10 0 0 0 6.84E+06 7.06E+06 - - - 2.6598 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.19570.19570.2 0.164 16-Sep R.MADLSELLK[136.11].E "sp|P30519|HMOX2_HUMAN,tr|I3L276|I3L276_HUMAN,tr|I3L159|I3L159_HUMAN,tr|I3L463|I3L463_HUMAN,tr|I3L4P8|I3L4P8_HUMAN,tr|A0A1B0GXH0|A0A1B0GXH0_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 8 1026.5511 0.83 6227 19570 2 1026.55292 514.2828 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 4.37 3682.2 - 893769 - - - 1.7895 - 1.635 0.193 - 196.3 1 2 0 0.0018 9 0 0 0 1.01E+07 1.23E+07 - - - 1.8883 0.8837 230117_WJC_METTL3_WT_vs_EV_F01.19571.19571.2 0.124 16-Sep L.GVLASDLQR.V "sp|O15381|NVL_HUMAN,tr|E9PH71|E9PH71_HUMAN,tr|F8WF01|F8WF01_HUMAN,tr|E7EWK7|E7EWK7_HUMAN,tr|E9PGD8|E9PGD8_HUMAN" 5 957.5243 0.71 6228 19571 2 957.526896 479.7694 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 5.84 3682.3 - 642500 - - - 2.6652 - 1.961 0.176 - 258 1 1 0 0.0026 9 0 0 0 4.40E+06 6.22E+06 - - - 2.2885 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.19572.19572.2 0.0467 16-Aug R.VVVLGLLPR.G "sp|Q15102|PA1B3_HUMAN,tr|M0R389|M0R389_HUMAN" 2 964.6433 1.39 6229 19572 2 964.646487 483.3289 Platelet-activating factor acetylhydrolase IB subunit alpha1 OS=Homo sapiens OX=9606 GN=PAFAH1B3 PE=1 SV=1 9.72 3682.4 - 635988 - - - 3.2655 - 1.693 0.288 - 205.3 1 2 0 0.0032 9 0 0 0 5.71E+06 4.10E+06 - - - 2.6904 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19573.19573.2 0.000842 18-Nov R.VLALEILPER[166.11].V sp|Q56A73|SPIN4_HUMAN 1 1161.6997 0.66 6230 19573 2 1161.703114 581.8571 Spindlin-4 OS=Homo sapiens OX=9606 GN=SPIN4 PE=1 SV=1 4.53 3682.6 - 608562 - - - 2.956 - 2.357 0.4 - 405.6 1 2 0 0.0034 10 0 0 0 4.39E+06 6.70E+06 - - - 4.3876 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19574.19574.2 0.000439 16-Oct K.WQALLVQIR[166.11].K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1135.6741 0.95 6231 19574 2 1135.676926 568.8443 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.75 3682.7 - 451185 - - - 2.4585 - 2.038 0.329 - 305.5 1 2 0 0.0028 9 0 0 0 1.81E+07 1.91E+07 - - - 3.5299 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.19576.19576.2 0.125 20-Jul R.FIMILTEHLVR[166.11].C "sp|Q09161|NCBP1_HUMAN,tr|X6R941|X6R941_HUMAN" 2 1380.7827 0.04 6233 19576 2 1380.784782 691.3986 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 6.75 3682.9 - 344350 - - - 1.5093 - 1.558 0.17 - 153.6 1 2 0 0.0021 11 0 0 0 9.65E+04 2.15E+06 - - - 1.4955 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.19586.19586.2 0.0503 22-Aug K.LILISTNGSFIR[166.11].L sp|Q6UXN9|WDR82_HUMAN 1 1342.7848 1 6240 19586 2 1342.788588 672.3997 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 9.75 3684.1 - 634143 - - - 2.8165 - 1.632 0.259 - 202.9 1 2 0 0.0038 12 0 0 0 1.66E+07 1.66E+07 - - - 2.2415 1 230117_WJC_METTL3_WT_vs_EV_F01.19587.19587.2 0.000293 26-Nov K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 3.36 6241 19587 2 1541.847016 771.9299 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3684.2 - 1.12E+06 - - - 1.0844 - 2.477 0.461 - 430.4 1 2 0 0.0017 14 0 0 0 1.74E+08 5.19E+07 - - - 4.7216 0.9969 230117_WJC_METTL3_WT_vs_EV_F01.19589.19589.2 0.045 22-Nov K.LILISTNGSFIR.L sp|Q6UXN9|WDR82_HUMAN 1 1332.7765 1 6243 19589 2 1332.783356 667.3955 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 9.75 3684.3 - 626384 - - - 5.1171 - 1.991 0.363 - 404.1 1 2 0 0.0068 12 0 0 0 1.66E+07 1.66E+07 - - - 3.5319 1 230117_WJC_METTL3_WT_vs_EV_F01.19590.19590.2 8.70E-07 13/26 K.LLDAVDTYIPVPAR[166.11].D sp|P49411|EFTU_HUMAN 1 1551.8536 3.36 6244 19590 2 1551.85647 776.9341 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3684.5 - 466300 - - - 1.8404 - 2.763 0.561 - 593.2 1 2 0 0.0029 14 0 0 0 1.74E+08 5.19E+07 - - - 5.734 0.999 230117_WJC_METTL3_WT_vs_EV_F01.19591.19591.2 2.06 12-Aug K.FDLIWNR.A "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|H0YEW4|H0YEW4_HUMAN,tr|A8MRA7|A8MRA7_HUMAN,tr|H0YD21|H0YD21_HUMAN" 5 962.4974 3.94 6245 19591 2 962.498176 482.256 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 5.84 3684.6 - 427989 - - - 0.8052 - 1.844 0.2 - 254.9 1 2 0 0.0008 7 0 0 0 9.49E+06 2.41E+06 - - - 2.4569 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.19592.19592.2 0.000854 28-Oct R.VGPDVVTDPAFLVTR.S sp|Q9NV31|IMP3_HUMAN 1 1584.8512 1.29 6246 19592 2 1584.848306 793.4329 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3684.7 - 241719 - - - -1.7995 - 2.152 0.411 - 256.6 1 2 0 -0.0029 15 0 0 0 1.02E+07 7.91E+06 - - - 3.96 1 230117_WJC_METTL3_WT_vs_EV_F01.19595.19595.2 0.000717 24-Dec R.IITLAGPTNAIFK[136.11].A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1365.8111 2.63 6247 19595 2 1365.815481 683.9128 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3685.1 - 1.43E+07 - - - 3.1805 - 2.515 0.441 - 447.2 1 2 0 0.0043 13 0 0 0 7.20E+08 2.74E+08 - - - 4.6639 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.19597.19597.2 0.0023 20-Dec K.LWDLASGTLYK.E sp|O75529|TAF5L_HUMAN 1 1265.6656 1.21 6249 19597 2 1265.669372 633.8401 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 5.83 3685.4 - 1.75E+06 - - - 2.9889 - 1.846 0.399 - 544.1 1 2 0 0.0038 11 0 0 0 2.06E+07 1.71E+07 - - - 3.6452 1 230117_WJC_METTL3_WT_vs_EV_F01.19598.19598.2 6.67E-07 20-Dec K.LWDLASGTLYK[136.11].E sp|O75529|TAF5L_HUMAN 1 1273.6798 1.22 6250 19598 2 1273.684945 637.8472 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 5.83 3685.5 - 1.68E+06 - - - 4.0481 - 2.312 0.521 - 466.1 1 2 0 0.0052 11 0 0 0 2.10E+07 1.72E+07 - - - 5.1548 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.19599.19599.2 0.0957 12-Jul K.LYSLLFR[166.11].R sp|Q9UDW1|QCR9_HUMAN 1 920.5359 1.42 6251 19599 2 920.539124 461.2752 Cytochrome b-c1 complex subunit 9 OS=Homo sapiens OX=9606 GN=UQCR10 PE=1 SV=3 8.75 3685.6 - 1.65E+06 - - - 3.4925 - 1.385 0.207 - 156.1 1 2 0 0.0032 7 0 0 0 1.57E+07 1.11E+07 - - - 1.6009 0.9897 230117_WJC_METTL3_WT_vs_EV_F01.19600.19600.2 0.491 16-Aug K.NLLNLDVIK.K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1040.623 1.06 6252 19600 2 1040.628187 521.3188 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3685.7 - 1.13E+06 - - - 4.9884 - 1.722 0.186 - 179.1 1 2 0 0.0052 9 0 0 0 4.59E+07 4.31E+07 - - - 1.9855 1 230117_WJC_METTL3_WT_vs_EV_F01.19601.19601.2 7.58E-05 13/22 K.QVVPFVYQTIVK.D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1419.8126 1.86 6253 19601 2 1419.817243 710.9136 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 3685.9 - 1.05E+06 - - - 3.2786 - 2.348 0.519 - 583.5 1 2 0 0.0047 12 0 0 0 1.24E+07 6.69E+06 - - - 5.1187 0.9887 230117_WJC_METTL3_WT_vs_EV_F01.19602.19602.2 0.27 14-Jul R.LWLLDDSK.T "sp|O43639|NCK2_HUMAN,sp|P16333|NCK1_HUMAN,tr|E7EPF5|E7EPF5_HUMAN,tr|E7ERP6|E7ERP6_HUMAN,tr|C9J0K5|C9J0K5_HUMAN,tr|C9K098|C9K098_HUMAN,tr|C9J869|C9J869_HUMAN,tr|C9JVV5|C9JVV5_HUMAN,tr|E9PEE2|E9PEE2_HUMAN,tr|H7C5C7|H7C5C7_HUMAN" 10 988.5229 1.53 6254 19602 2 988.527792 495.2687 Cytoplasmic protein NCK2 OS=Homo sapiens OX=9606 GN=NCK2 PE=1 SV=2 4.21 3686 - 777685 - - - 4.9013 - 1.606 0.186 - 139.2 1 2 0 0.0048 8 0 0 0 5.48E+06 3.57E+06 - - - 1.8421 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19604.19604.2 0.000239 22-Oct K.QVVPFVYQTIVK[136.11].D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1427.8268 1.86 6256 19604 2 1427.831414 714.9207 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 3686.3 - 716981 - - - 3.2399 - 1.923 0.484 - 241.3 1 2 0 0.0046 12 0 0 0 1.24E+07 6.69E+06 - - - 4.3349 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19606.19606.2 0.000117 28-Nov R.VGPDVVTDPAFLVTR[166.11].S sp|Q9NV31|IMP3_HUMAN 1 1594.8594 1.29 6258 19606 2 1594.864662 798.437 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3686.5 - 324049 - - - 3.2818 - 1.842 0.427 - 282.5 1 2 0 0.0052 15 0 0 0 1.02E+07 7.91E+06 - - - 3.695 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19607.19607.2 0.00589 20-Aug K.IDAELVLPTIR.S "sp|O95985|TOP3B_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 2 1238.7234 1.1 6259 19607 2 1238.725599 620.369 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 4.37 3686.7 - 273320 - - - 1.7445 - 1.77 0.394 - 145.7 1 2 0 0.0022 11 0 0 0 5.31E+06 4.83E+06 - - - 3.495 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19612.19612.2 0.0252 16-Sep K.NLLNLDVIK[136.11].K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1048.6372 1.06 6263 19612 2 1048.63962 525.3259 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3687.2 - 4.82E+06 - - - 2.3116 - 1.929 0.268 - 268.7 1 2 0 0.0024 9 0 0 0 4.59E+07 4.31E+07 - - - 2.9204 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19613.19613.2 0.000349 16-Sep K.WQALLVQIR.K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1125.6659 0.89 6264 19613 2 1125.669382 563.8402 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.75 3687.3 - 4.61E+06 - - - 3.1253 - 1.991 0.451 - 328.8 1 2 0 0.0035 9 0 0 0 1.70E+07 1.91E+07 - - - 4.3632 0.97 230117_WJC_METTL3_WT_vs_EV_F01.19616.19616.2 2.32 26-Jul K.VVIGMDVAASEFYR[166.11].N "sp|P13929|ENOB_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN" 2 1565.7787 2.06 6267 19616 2 1565.78103 783.8966 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.37 3687.6 - 2.01E+06 - - - 1.4657 - 1.097 0.063 - 105 1 2 0 0.0023 14 0 0 0 5.47E+07 2.65E+07 - - - -0.2621 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19618.19618.3 0.00252 Dec-52 K.LLDAVDTYIPVPAR[166.11].D sp|P49411|EFTU_HUMAN 1 1551.8536 3.18 6269 19618 3 1551.8579 518.2918 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3687.7 - 1.18E+06 - - - 2.7619 - 1.624 0.347 - 134.3 1 2 0 0.0043 14 0 0 0 2.83E+07 8.90E+06 - - - 3.6961 1 230117_WJC_METTL3_WT_vs_EV_F01.19620.19620.2 3.28E-07 22-Oct K.LFGYEPTIYYPK[136.11].R "sp|Q8NCW5|NNRE_HUMAN,tr|A0A7P0Z426|A0A7P0Z426_HUMAN,tr|Q5T3I4|Q5T3I4_HUMAN,tr|A0A7P0T9Y2|A0A7P0T9Y2_HUMAN,tr|A0A7P0TAG8|A0A7P0TAG8_HUMAN,tr|Q5T3I3|Q5T3I3_HUMAN" 6 1497.7635 1.35 6271 19620 2 1497.76794 749.889 NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2 6 3688 - 1.09E+06 - - - 2.9517 - 2.021 0.529 - 295.1 1 2 0 0.0044 12 0 0 0 1.09E+07 8.11E+06 - - - 4.7981 1 230117_WJC_METTL3_WT_vs_EV_F01.19626.19626.2 7.48E-07 22-Oct K.MYLGYEYVTAIR.N sp|P02787|TRFE_HUMAN 1 1477.7275 -1 6277 19626 2 1477.729545 739.871 Serotransferrin OS=Homo sapiens OX=9606 GN=TF PE=1 SV=3 5.75 3688.8 - 401788 - - - 1.3588 - 2.239 0.49 - 326.3 1 2 0 0.002 12 0 0 0 0.00E+00 0.00E+00 - - - 4.7803 0.9941 230117_WJC_METTL3_WT_vs_EV_F01.19627.19627.2 0.129 16-Jun R.VVVLGLLPR[166.11].G "sp|Q15102|PA1B3_HUMAN,tr|M0R389|M0R389_HUMAN" 2 974.6516 1.39 6278 19627 2 974.653339 488.3331 Platelet-activating factor acetylhydrolase IB subunit alpha1 OS=Homo sapiens OX=9606 GN=PAFAH1B3 PE=1 SV=1 9.72 3688.9 - 385719 - - - 1.777 - 1.287 0.169 - 71.4 2 2 0 0.0017 9 0 0 0 5.71E+06 4.10E+06 - - - 0.8842 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.19632.19632.3 5.01E-06 17/52 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 3.18 6281 19632 3 1541.849206 514.9557 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3689.4 - 3.02E+06 - - - 2.5048 - 2.579 0.44 - 284.8 1 2 0 0.0039 14 0 0 0 2.83E+07 8.90E+06 - - - 5.9622 1 230117_WJC_METTL3_WT_vs_EV_F01.19633.19633.2 0.00018 20-Dec R.LLESLDQLELR.V sp|O95816|BAG2_HUMAN 1 1327.7347 8.95 6282 19633 2 1327.737893 664.8746 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.14 3689.4 - 2.21E+06 - - - 2.3815 - 2.556 0.454 - 521.9 1 2 0 0.0032 11 0 0 0 2.83E+08 3.16E+07 - - - 4.932 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.19634.19634.2 0.0343 14-Sep R.LWDFIENR.E "sp|Q9H000|MKRN2_HUMAN,tr|A0A7I2V5D2|A0A7I2V5D2_HUMAN,tr|A0A7I2YQI0|A0A7I2YQI0_HUMAN,tr|C9J494|C9J494_HUMAN" 4 1091.54 1.9 6283 19634 2 1091.538912 546.7773 Probable E3 ubiquitin-protein ligase makorin-2 OS=Homo sapiens OX=9606 GN=MKRN2 PE=1 SV=2 4.37 3689.5 - 1.17E+06 - - - -0.9913 - 1.914 0.347 - 298.4 1 2 0 -0.0011 8 0 0 0 1.61E+07 8.49E+06 - - - 3.5615 1 230117_WJC_METTL3_WT_vs_EV_F01.19638.19638.2 1.10E-07 13/20 K.IDAELVLPTIR[166.11].S "sp|O95985|TOP3B_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 2 1248.7317 1.09 6287 19638 2 1248.734832 625.3731 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 4.37 3690 - 375295 - - - 2.5017 - 2.661 0.555 - 977.7 1 2 0 0.0031 11 0 0 0 5.27E+06 4.83E+06 - - - 5.7869 1 230117_WJC_METTL3_WT_vs_EV_F01.19642.19642.2 4.23E-05 22-Dec K.LFGYEPTIYYPK.R "sp|Q8NCW5|NNRE_HUMAN,tr|A0A7P0Z426|A0A7P0Z426_HUMAN,tr|Q5T3I4|Q5T3I4_HUMAN,tr|A0A7P0T9Y2|A0A7P0T9Y2_HUMAN,tr|A0A7P0TAG8|A0A7P0TAG8_HUMAN,tr|Q5T3I3|Q5T3I3_HUMAN" 6 1489.7493 1.35 6290 19642 2 1489.751417 745.8819 NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2 6 3690.6 - 1.26E+06 - - - 1.4083 - 2.357 0.492 - 416.3 1 2 0 0.0021 12 0 0 0 1.09E+07 8.11E+06 - - - 4.9302 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.19645.19645.2 0.0653 18-Nov R.NALPALLIYK.G sp|Q13371|PHLP_HUMAN 1 1114.675 2.32 6292 19645 2 1114.678789 558.3448 Phosducin-like protein OS=Homo sapiens OX=9606 GN=PDCL PE=1 SV=3 8.59 3690.9 - 2.53E+06 - - - 3.3714 - 1.44 0.258 - 352.5 1 2 0 0.0038 10 0 0 0 7.57E+06 3.27E+06 - - - 1.9632 0.996 230117_WJC_METTL3_WT_vs_EV_F01.19646.19646.2 0.00689 14-Sep R.LWDFIENR[166.11].E "sp|Q9H000|MKRN2_HUMAN,tr|A0A7I2V5D2|A0A7I2V5D2_HUMAN,tr|A0A7I2YQI0|A0A7I2YQI0_HUMAN,tr|C9J494|C9J494_HUMAN" 4 1101.5483 1.89 6293 19646 2 1101.544763 551.7814 Probable E3 ubiquitin-protein ligase makorin-2 OS=Homo sapiens OX=9606 GN=MKRN2 PE=1 SV=2 4.37 3690.9 - 1.49E+06 - - - -3.1783 - 1.785 0.394 - 210.4 1 2 0 -0.0035 8 0 0 0 1.60E+07 8.49E+06 - - - 3.6975 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19650.19650.2 6.59E-05 20-Oct R.LLESLDQLELR[166.11].V sp|O95816|BAG2_HUMAN 1 1337.743 8.95 6297 19650 2 1337.74394 669.8788 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.14 3691.3 - 1.17E+06 - - - 0.7019 - 2.224 0.409 - 292.2 1 2 0 0.0009 11 0 0 0 2.83E+08 3.16E+07 - - - 4.2239 1 230117_WJC_METTL3_WT_vs_EV_F01.19652.19652.2 8.20E-06 14/22 R.LLTWVIGTGSPR[166.11].L sp|Q92616|GCN1_HUMAN 1 1308.7429 1.18 6299 19652 2 1308.743955 655.3787 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.75 3691.4 - 1.12E+06 - - - 0.774 - 2.385 0.535 - 827.7 1 2 0 0.001 12 0 0 0 6.50E+06 5.52E+06 - - - 5.2792 1 230117_WJC_METTL3_WT_vs_EV_F01.19654.19654.2 1.04E-08 13/24 K.LVDSMGWELASVR[166.11].R "sp|O94761|RECQ4_HUMAN,tr|A0A087WTJ0|A0A087WTJ0_HUMAN,tr|A0A087X072|A0A087X072_HUMAN" 3 1471.7369 0.77 6301 19654 2 1471.734939 736.8757 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.37 3691.7 - 617589 - - - -1.3121 - 2.273 0.539 - 542.9 1 2 0 -0.0019 13 0 0 0 2.00E+06 2.59E+06 - - - 5.1288 0.9933 230117_WJC_METTL3_WT_vs_EV_F01.19656.19656.2 0.00669 12-Jun R.EFEFLMR.Q sp|P85037|FOXK1_HUMAN 1 970.4582 2.57 6303 19656 2 970.456389 486.2364 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 4.53 3691.9 - 440984 - - - -1.9063 - 1.323 0.289 - 142.5 1 2 0 -0.0019 7 0 0 0 3.05E+06 1.19E+06 - - - 2.0619 0.9633 230117_WJC_METTL3_WT_vs_EV_F01.19658.19658.2 0.531 12-May R.EFEFLMR[166.11].Q sp|P85037|FOXK1_HUMAN 1 980.4665 2.57 6305 19658 2 980.464109 491.2405 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 4.53 3692.2 - 293471 - - - -2.4478 - 1.02 0.261 - 64.4 2 2 0 -0.0024 7 0 0 0 3.05E+06 1.19E+06 - - - 0.8963 1 230117_WJC_METTL3_WT_vs_EV_F01.19670.19670.2 0.000412 20-Nov K.VGEVTYVELFK[136.11].D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1290.6951 1.83 6315 19670 2 1290.698998 646.3548 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.53 3693.3 - 530215 - - - 3.0162 - 2.413 0.482 - 594.7 1 2 0 0.0039 11 0 0 0 1.28E+08 6.98E+07 - - - 4.9828 1 230117_WJC_METTL3_WT_vs_EV_F01.19674.19674.2 6.99E-07 22-Nov R.ELYLEDSPLELK.L sp|Q8TEM1|PO210_HUMAN 1 1447.7446 2.51 6319 19674 2 1447.748058 724.8796 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4 3693.9 - 305577 - - - 2.3699 - 2.413 0.526 - 373 1 2 0 0.0034 12 0 0 0 4.15E+06 1.65E+06 - - - 5.2427 1 230117_WJC_METTL3_WT_vs_EV_F01.19675.19675.2 1.67E-05 15/26 R.LIVVLEGASLETVK[136.11].V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1477.8847 0.95 6320 19675 2 1477.885926 739.9496 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3694 - 297747 - - - 0.8323 - 2.93 0.492 - 703.4 1 2 0 0.0012 14 0 0 0 3.59E+06 3.79E+06 - - - 5.3722 0.8772 230117_WJC_METTL3_WT_vs_EV_F01.19676.19676.2 1.43 14-Jul K.IPEFIAFR.N sp|Q14CX7|NAA25_HUMAN 1 991.5491 0.06 6321 19676 2 991.554467 496.7818 "N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA25 PE=1 SV=1" 6 3694.1 - 213257 - - - 5.4107 - 1.176 0.091 - 104.1 1 2 0 0.0054 8 0 0 0 2.46E+06 3.86E+07 - - - 0.2004 1 230117_WJC_METTL3_WT_vs_EV_F01.19679.19679.2 0.000154 22-Nov R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.1 6323 19679 2 1315.791718 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3694.5 - 350779 - - - 4.0622 - 2.098 0.495 - 356.6 1 2 0 0.0053 12 0 0 0 2.42E+07 2.19E+07 - - - 4.645 0.9949 230117_WJC_METTL3_WT_vs_EV_F01.19680.19680.2 0.506 12-Sep R.YVLSFLR.T "sp|Q96SI1|KCD15_HUMAN,tr|V9GYY8|V9GYY8_HUMAN,tr|K7EN63|K7EN63_HUMAN" 3 896.512 3.18 6324 19680 2 896.514036 449.2633 BTB\POZ domain-containing protein KCTD15 OS=Homo sapiens OX=9606 GN=KCTD15 PE=1 SV=1 8.75 3694.6 - 314687 - - - 2.2833 - 1.515 0.104 - 262.1 1 2 0 0.002 7 0 0 0 3.27E+06 1.03E+06 - - - 1.1248 1 230117_WJC_METTL3_WT_vs_EV_F01.19681.19681.2 3.90E-05 18-Sep R.AEVVSLLLDR.K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1113.6394 1.26 6325 19681 2 1113.642997 557.827 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3694.7 - 3.81E+06 - - - 3.2533 - 2.114 0.483 - 304.1 1 2 0 0.0036 10 0 0 0 4.37E+07 3.46E+07 - - - 4.6968 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19682.19682.2 0.0229 18-Dec R.AEVVSLLLDR[166.11].K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1123.6476 1.56 6326 19682 2 1123.65091 562.8311 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3694.8 - 3.13E+06 - - - 2.9066 - 2.169 0.399 - 716.5 1 2 0 0.0033 10 0 0 0 5.44E+07 3.49E+07 - - - 4.1482 1 230117_WJC_METTL3_WT_vs_EV_F01.19689.19689.2 0.000117 15/26 R.LIVVLEGASLETVK.V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1469.8705 0.95 6333 19689 2 1469.874687 735.9425 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3695.6 - 624648 - - - 2.8513 - 3.048 0.554 - 725.9 1 2 0 0.0042 14 0 0 0 3.59E+06 3.79E+06 - - - 5.9283 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19690.19690.2 0.00377 24-Dec R.LSAYVSYGGLLMR.L "sp|P52434|RPAB3_HUMAN,tr|C9JLU1|C9JLU1_HUMAN" 2 1428.7435 1.09 6334 19690 2 1428.744615 715.379 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4" 8.59 3695.7 - 622999 - - - 0.765 - 2.303 0.417 - 432.2 1 2 0 0.0011 13 0 0 0 3.72E+06 3.41E+06 - - - 4.2616 1 230117_WJC_METTL3_WT_vs_EV_F01.19691.19691.2 0.00045 22-Dec R.LLEITEGSEFLR.L "sp|Q86U28|ISCA2_HUMAN,tr|J3QSS7|J3QSS7_HUMAN" 2 1405.7453 3.72 6335 19691 2 1405.74875 703.8799 "Iron-sulfur cluster assembly 2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=ISCA2 PE=1 SV=2" 4.25 3695.8 - 519128 - - - 2.4571 - 2.34 0.45 - 468.8 1 2 0 0.0035 12 0 0 0 3.86E+06 1.04E+06 - - - 4.6005 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.19692.19692.2 2.81E-05 13/24 R.LSAYVSYGGLLMR[166.11].L "sp|P52434|RPAB3_HUMAN,tr|C9JLU1|C9JLU1_HUMAN" 2 1438.7518 1.09 6336 19692 2 1438.757461 720.3832 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4" 8.59 3696 - 488077 - - - 3.9402 - 2.378 0.45 - 514.1 1 2 0 0.0057 13 0 0 0 3.72E+06 3.41E+06 - - - 4.5862 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.19695.19695.2 1.72 14-Aug R.TLTDLLLR.F "sp|O76024|WFS1_HUMAN,tr|A0A669KAX3|A0A669KAX3_HUMAN,tr|H0Y9G5|H0Y9G5_HUMAN" 3 943.5702 -1 6339 19695 2 943.573085 472.7924 Wolframin OS=Homo sapiens OX=9606 GN=WFS1 PE=1 SV=2 5.5 3696.4 - 239290 - - - 3.0236 - 1.286 0.21 - 120.5 1 2 0 0.0029 8 0 0 0 0.00E+00 0.00E+00 - - - 1.3498 0.9818 230117_WJC_METTL3_WT_vs_EV_F01.19697.19697.2 0.289 24-Jun K.LVDSMGWELASVR.R "sp|O94761|RECQ4_HUMAN,tr|A0A087WTJ0|A0A087WTJ0_HUMAN,tr|A0A087X072|A0A087X072_HUMAN" 3 1461.7286 0.81 6341 19697 2 1461.734674 731.8716 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.37 3696.6 - 212302 - - - 4.1554 - 1.279 0.225 - 40.4 5 2 0 0.0061 13 0 0 0 2.09E+06 2.59E+06 - - - 1.0203 1 230117_WJC_METTL3_WT_vs_EV_F01.19701.19701.2 0.0114 13/20 R.VLITTLITAGR[166.11].L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1166.7262 1.02 6344 19701 2 1166.728832 584.3704 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3697.1 - 3.18E+06 - - - 2.231 - 2.638 0.447 - 609.8 1 2 0 0.0026 11 0 0 0 1.12E+07 1.10E+07 - - - 4.9659 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19702.19702.2 0.116 20-Nov R.VLITTLITAGR.L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1156.718 1.04 6345 19702 2 1156.72049 579.3663 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3697.2 - 3.02E+06 - - - 2.1881 - 2.24 0.368 - 399.7 1 2 0 0.0025 11 0 0 0 1.14E+07 1.10E+07 - - - 3.94 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.19703.19703.2 0.00328 22-Dec K.DAGVIAGLNVLR.L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1196.6877 0.07 6346 19703 2 1196.69252 599.3511 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3697.2 - 2.79E+06 - - - 4.0102 - 1.562 0.354 - 353.3 1 2 0 0.0048 12 0 0 0 6.08E+06 8.26E+07 - - - 2.8276 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19707.19707.2 0.0165 18-Oct R.EALLAALGYK[136.11].N sp|Q9BU76|MMTA2_HUMAN 1 1055.6106 0.67 6350 19707 2 1055.613402 528.8126 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3697.6 - 1.44E+06 - - - 2.6099 - 2.338 0.337 - 291.1 1 2 0 0.0028 10 0 0 0 3.33E+07 5.00E+07 - - - 3.8999 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.19708.19708.2 0.0706 14-Sep K.INFDALLK.F "sp|P55061|BI1_HUMAN,tr|F8VX73|F8VX73_HUMAN,tr|F8W201|F8W201_HUMAN,tr|F8VSI7|F8VSI7_HUMAN,tr|F8VVJ4|F8VVJ4_HUMAN,tr|F8VPI1|F8VPI1_HUMAN,tr|F8W086|F8W086_HUMAN,tr|F8VQQ5|F8VQQ5_HUMAN,tr|F8VQW0|F8VQW0_HUMAN,tr|F8VR05|F8VR05_HUMAN,tr|F8W1G3|F8W1G3_HUMAN" 11 932.5331 1.35 6351 19708 2 932.5357 467.2738 Bax inhibitor 1 OS=Homo sapiens OX=9606 GN=TMBIM6 PE=1 SV=2 5.84 3697.8 - 1.27E+06 - - - 2.7688 - 1.583 0.295 - 159.4 1 2 0 0.0026 8 0 0 0 2.27E+06 1.68E+06 - - - 2.6044 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.19709.19709.2 0.0144 18-Sep R.EALLAALGYK.N sp|Q9BU76|MMTA2_HUMAN 1 1047.5964 0.74 6352 19709 2 1047.601103 524.8055 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3697.9 - 1.24E+06 - - - 4.4445 - 2.182 0.346 - 187.8 1 2 0 0.0047 10 0 0 0 3.33E+07 4.48E+07 - - - 3.773 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.19715.19715.2 0.00139 12-Jul R.FANYIDK.V "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 869.4283 1.28 6358 19715 2 869.43058 435.7214 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.83 3698.6 - 602383 - - - 2.6006 - 1.492 0.351 - 107.5 1 2 0 0.0023 7 0 0 0 2.90E+06 2.26E+06 - - - 2.9006 0.9862 230117_WJC_METTL3_WT_vs_EV_F01.19717.19717.2 1.72 12-Jul R.AFLPLLK.A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 800.516 1.3 6360 19717 2 800.516813 401.2653 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3698.9 - 428464 - - - 1.0019 - 1.22 0.081 - 225.6 1 2 0 0.0008 7 0 0 0 2.13E+07 1.63E+07 - - - 0.2691 0.9941 230117_WJC_METTL3_WT_vs_EV_F01.19720.19720.2 4.3 12-Jun R.EIFDLIR.S "sp|Q9Y3D0|CIA2B_HUMAN,tr|H3BNV7|H3BNV7_HUMAN,tr|J3KS95|J3KS95_HUMAN" 3 904.5018 2.42 6362 19720 2 904.50359 453.2582 Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1 4.37 3699.3 - 4.55E+06 - - - 1.9591 - 1.222 0.168 - 195.5 1 2 0 0.0018 7 0 0 0 3.59E+07 1.48E+07 - - - 0.9166 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.19726.19726.2 0.00149 20-Nov K.VAPGFQFFATR[166.11].R sp|Q9NU22|MDN1_HUMAN 1 1249.6483 1.07 6368 19726 2 1249.65399 625.8314 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 9.72 3699.8 - 957282 - - - 4.5429 - 2 0.35 - 480 1 2 0 0.0057 11 0 0 0 4.86E+06 4.55E+06 - - - 3.4994 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.19728.19728.2 0.341 14-Aug K.VLIVVPFR.E "sp|Q68CQ4|UTP25_HUMAN,tr|H7C2R4|H7C2R4_HUMAN" 2 941.6062 1.56 6370 19728 2 941.608306 471.8104 U3 small nucleolar RNA-associated protein 25 homolog OS=Homo sapiens OX=9606 GN=UTP25 PE=1 SV=2 9.72 3700.1 - 409572 - - - 2.2122 - 1.697 0.22 - 151.2 1 2 0 0.0021 8 0 0 0 2.76E+06 1.77E+06 - - - 2.2603 1 230117_WJC_METTL3_WT_vs_EV_F01.19729.19729.2 6.83E-06 13/22 K.FATEDEAWAFVR.K sp|O60930|RNH1_HUMAN 1 1440.6674 1.59 6371 19729 2 1440.66782 721.341 Ribonuclease H1 OS=Homo sapiens OX=9606 GN=RNASEH1 PE=1 SV=2 4.14 3700.2 - 377752 - - - 0.3054 - 2.705 0.557 - 581.6 1 2 0 0.0004 12 0 0 0 1.74E+06 1.10E+06 - - - 5.7731 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.19730.19730.2 0.00168 20-Sep K.YAVLYQPLFDK.R "sp|P55209|NP1L1_HUMAN,tr|F8VUX1|F8VUX1_HUMAN,tr|F8W543|F8W543_HUMAN,tr|F8W118|F8W118_HUMAN,tr|F8VRJ2|F8VRJ2_HUMAN,tr|F8W0J6|F8W0J6_HUMAN,tr|F8VV59|F8VV59_HUMAN,tr|B7Z9C2|B7Z9C2_HUMAN,tr|F8VXI6|F8VXI6_HUMAN,tr|H0YHC3|H0YHC3_HUMAN,tr|H0YIV4|H0YIV4_HUMAN,tr|F5H4R6|F5H4R6_HUMAN,tr|H0YH88|H0YH88_HUMAN,tr|F8W020|F8W020_HUMAN,tr|F8VVB5|F8VVB5_HUMAN,tr|F8VY35|F8VY35_HUMAN" 16 1355.7125 2.65 6372 19730 2 1355.715348 678.8635 Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1 5.83 3700.4 - 374947 - - - 2.072 - 1.671 0.306 - 276.3 1 2 0 0.0028 11 0 0 0 3.11E+07 1.17E+07 - - - 2.6892 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.19741.19741.2 0.173 14-Aug R.YELALILK[136.11].A sp|P82932|RT06_HUMAN 1 969.599 2.55 6382 19741 2 969.599148 485.8068 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3701.5 - 415372 - - - 0.133 - 1.544 0.282 - 178.5 1 2 0 0.0001 8 0 0 0 1.89E+07 7.40E+06 - - - 2.4339 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.19746.19746.2 0.000247 18-Dec R.IINDLLQSLR.S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1183.6925 2.06 6385 19746 2 1183.69793 592.8535 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3702 - 1.89E+06 - - - 4.611 - 2.361 0.206 - 456.2 1 2 0 0.0055 10 0 0 0 1.63E+08 7.91E+07 - - - 2.9588 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.19747.19747.2 0.000502 14-Oct R.YELALILK.A sp|P82932|RT06_HUMAN 1 961.5848 2.55 6386 19747 2 961.588345 481.7997 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3702.2 - 808900 - - - 3.6669 - 1.782 0.358 - 256.1 1 2 0 0.0035 8 0 0 0 1.89E+07 7.40E+06 - - - 3.4265 0.9956 230117_WJC_METTL3_WT_vs_EV_F01.19750.19750.2 0.0323 20-Nov R.LALVISELEGK[136.11].A "sp|Q12899|TRI26_HUMAN,tr|A2AE48|A2AE48_HUMAN" 2 1178.7002 1.31 6389 19750 2 1178.70685 590.3574 Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1 4.53 3702.5 - 317689 - - - 5.6503 - 2.457 0.282 - 343.7 1 2 0 0.0067 11 0 0 0 8.50E+06 6.47E+06 - - - 3.5536 0.997 230117_WJC_METTL3_WT_vs_EV_F01.19754.19754.2 0.143 14-Aug R.LSFFGLEK.L "sp|Q9ULF5|S39AA_HUMAN,tr|E7EV45|E7EV45_HUMAN,tr|E7ENT5|E7ENT5_HUMAN" 3 939.5066 0.62 6393 19754 2 939.509046 470.7606 Zinc transporter ZIP10 OS=Homo sapiens OX=9606 GN=SLC39A10 PE=1 SV=2 6 3703 - 289702 - - - 2.6365 - 1.373 0.232 - 149.8 1 2 0 0.0025 8 0 0 0 2.81E+06 4.56E+06 - - - 1.7098 1 230117_WJC_METTL3_WT_vs_EV_F01.19766.19766.2 0.00107 18-Nov R.LGLEDFESLK[136.11].V sp|Q15208|STK38_HUMAN 1 1157.606 0.55 6404 19766 2 1157.610201 579.8103 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3704.4 - 770059 - - - 3.6679 - 2.28 0.447 - 265.7 1 2 0 0.0042 10 0 0 0 1.76E+08 3.18E+08 - - - 4.6417 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.19769.19769.2 0.0025 13/20 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 5.24 6407 19769 2 1276.709067 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3704.7 - 580267 - - - 4.9847 - 2.699 0.376 - 860.6 1 2 0 0.0064 11 0 0 0 8.58E+06 1.64E+06 - - - 4.5021 0.9829 230117_WJC_METTL3_WT_vs_EV_F01.19770.19770.2 0.00608 14-Aug R.LEDPLLWR.T sp|Q96EX3|DC2I2_HUMAN 1 1040.5655 0.82 6408 19770 2 1040.574214 521.29 Cytoplasmic dynein 2 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC2I2 PE=1 SV=2 4.37 3704.9 - 413792 - - - 8.3926 - 1.822 0.396 - 175.8 1 2 0 0.0087 8 0 0 0 2.42E+06 2.94E+06 - - - 3.7725 1 230117_WJC_METTL3_WT_vs_EV_F01.19772.19772.2 1.55E-06 18-Nov K.LFGYEMAEFK[136.11].V sp|Q9UKD2|MRT4_HUMAN 1 1241.5882 0.7 6410 19772 2 1241.592504 621.8014 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 4.53 3705.1 - 365580 - - - 3.4689 - 1.815 0.58 - 266.9 1 2 0 0.0043 10 0 0 0 4.57E+06 6.57E+06 - - - 4.9874 0.9125 230117_WJC_METTL3_WT_vs_EV_F01.19774.19774.2 0.00719 18-Sep R.LGLEDFESLK.V sp|Q15208|STK38_HUMAN 1 1149.5918 0.55 6412 19774 2 1150.599307 575.8032 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3705.3 - 386681 - - - 876.4433 - 1.896 0.424 - 152.6 1 2 0 1.0076 10 0 0 0 1.76E+08 3.18E+08 - - - 3.642 0.998 230117_WJC_METTL3_WT_vs_EV_F01.19775.19775.2 0.59 14-Aug K.VAIIIPFR.N "sp|P15291|B4GT1_HUMAN,sp|O43286|B4GT5_HUMAN,tr|Q86XA6|Q86XA6_HUMAN" 3 927.5906 0.31 6413 19775 2 927.593917 464.8026 "Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5" 9.72 3705.4 - 188559 - - - 3.605 - 1.789 0.259 - 207.3 1 2 0 0.0033 8 0 0 0 7.09E+06 2.32E+07 - - - 2.7072 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.19781.19781.2 0.664 18-Oct R.IINDLLQSLR[166.11].S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1193.7007 2.06 6417 19781 2 1193.705995 597.8576 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3706.3 - 6.17E+06 - - - 4.4006 - 2.174 0.171 - 244.8 1 2 0 0.0053 10 0 0 0 1.63E+08 7.91E+07 - - - 2.47 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.19783.19783.2 0.161 14-Jul K.VAIIIPFR[166.11].N "sp|P15291|B4GT1_HUMAN,sp|O43286|B4GT5_HUMAN,tr|Q86XA6|Q86XA6_HUMAN" 3 937.5988 0.95 6419 19783 2 937.601218 469.8067 "Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5" 9.72 3706.4 - 539041 - - - 2.5331 - 1.719 0.171 - 173 1 2 0 0.0024 8 0 0 0 6.13E+06 6.44E+06 - - - 1.9371 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19784.19784.2 0.000662 22-Jul K.VLLSPDYLPAMR.R sp|Q7Z6Z7|HUWE1_HUMAN 1 1373.7377 3.02 6420 19784 2 1373.741385 687.8761 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.81 3706.5 - 408664 - - - 2.6766 - 1.809 0.396 - 119.6 1 2 0 0.0037 12 0 0 0 6.77E+06 2.24E+06 - - - 3.5244 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.19795.19795.2 0.00127 18-Nov R.IEGLLAAFPK.L "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|E9PK34|E9PK34_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 4 1057.6172 2.49 6429 19795 2 1057.620703 529.8159 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6 3707.7 - 806437 - - - 3.3292 - 2.287 0.374 - 284.4 1 2 0 0.0035 10 0 0 0 1.71E+07 6.84E+06 - - - 4.1113 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.19796.19796.2 0.00689 16-Sep K.ALEVYDLIR.T "sp|Q9H5X1|CIA2A_HUMAN,tr|H0YKV4|H0YKV4_HUMAN" 2 1090.6023 1.44 6430 19796 2 1090.605571 546.3084 Cytosolic iron-sulfur assembly component 2A OS=Homo sapiens OX=9606 GN=CIAO2A PE=1 SV=1 4.37 3707.8 - 831511 - - - 3.0359 - 2.035 0.342 - 370 1 2 0 0.0033 9 0 0 0 1.04E+07 7.23E+06 - - - 3.6215 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.19803.19803.2 0.000144 18-Dec K.VAEITELILK[136.11].A "sp|Q06265|EXOS9_HUMAN,tr|D6R905|D6R905_HUMAN,tr|H0Y9L5|H0Y9L5_HUMAN,tr|D6RIY6|D6RIY6_HUMAN" 4 1135.6944 1.23 6437 19803 2 1135.700574 568.8545 Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3 4.53 3708.7 - 496072 - - - 5.4575 - 2.375 0.418 - 472.8 1 2 0 0.0062 10 0 0 0 1.88E+07 1.53E+07 - - - 4.5409 1 230117_WJC_METTL3_WT_vs_EV_F01.19804.19804.2 1.54E-08 26-Nov K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 2.79 6438 19804 2 1762.800838 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3708.8 - 457729 - - - 3.2551 - 2.362 0.675 - 362.1 1 2 0 0.0057 14 0 0 0 4.56E+06 1.63E+06 - - - 6.1816 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.19805.19805.2 0.0071 18-Oct R.TALYNYIFAK.K "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1202.6336 1.49 6439 19805 2 1202.640462 602.3241 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 8.17 3709 - 440185 - - - 5.7391 - 2.072 0.39 - 300.9 1 2 0 0.0069 10 0 0 0 5.18E+06 3.48E+06 - - - 3.9529 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.19807.19807.2 0.563 22-Oct R.AVVMTPVPLFSK.Q sp|O14976|GAK_HUMAN 1 1287.7261 2.26 6441 19807 2 1287.729733 644.8703 Cyclin-G-associated kinase OS=Homo sapiens OX=9606 GN=GAK PE=1 SV=2 8.8 3709.2 - 363713 - - - 2.836 - 1.796 0.093 - 277.3 1 2 0 0.0037 12 0 0 0 3.30E+06 1.46E+06 - - - 1.2675 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.19809.19809.2 0.00211 22-Oct R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.08 6443 19809 2 1323.807712 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3709.5 - 296818 - - - 5.3928 - 1.712 0.439 - 260.3 1 2 0 0.0071 12 0 0 0 2.72E+06 2.51E+06 - - - 3.6959 1 230117_WJC_METTL3_WT_vs_EV_F01.19810.19810.2 2.60E-06 13/26 K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 2.79 6444 19810 2 1772.815198 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3709.6 - 230398 - - - 6.6719 - 2.64 0.639 - 597.2 1 2 0 0.0118 14 0 0 0 4.56E+06 1.63E+06 - - - 6.1931 1 230117_WJC_METTL3_WT_vs_EV_F01.19811.19811.3 2.02E-10 20/76 K.FEAHPNDLYVEGLPENIPFR.S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2356.1488 7.61 6445 19811 3 2356.161166 786.3902 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3709.7 - 218336 - - - 5.2497 - 3.854 0.663 - 358.4 1 2 0 0.0124 20 0 0 0 7.54E+06 9.90E+05 - - - 9.2013 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19812.19812.2 0.00012 14/24 R.LENLGIPEEELLR.Q sp|Q01658|NC2B_HUMAN 1 1523.8195 2.3 6446 19812 2 1523.822992 762.917 Protein Dr1 OS=Homo sapiens OX=9606 GN=DR1 PE=1 SV=1 4.09 3709.9 - 212279 - - - 2.2765 - 2.865 0.363 - 555 1 2 0 0.0035 13 0 0 0 1.95E+06 8.50E+05 - - - 4.4225 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.19813.19813.2 0.0359 14-Aug R.GLDIYVWR[166.11].G sp|Q13045|FLII_HUMAN 1 1030.5475 1.03 6447 19813 2 1030.550766 516.281 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3710 - 205984 - - - 3.1343 - 1.731 0.325 - 183.1 1 2 0 0.0032 8 0 0 0 6.12E+06 5.92E+06 - - - 3.0953 0.9925 230117_WJC_METTL3_WT_vs_EV_F01.19820.19820.2 0.211 14-May R.LLFFAPTR.R sp|Q07820|MCL1_HUMAN 1 963.5542 3.29 6453 19820 2 963.554503 482.7844 Induced myeloid leukemia cell differentiation protein Mcl-1 OS=Homo sapiens OX=9606 GN=MCL1 PE=1 SV=3 9.75 3710.7 - 1.09E+06 - - - 0.3269 - 1.317 0.16 - 93.3 3 2 0 0.0003 8 0 0 0 7.30E+06 2.22E+06 - - - 0.84 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.19821.19821.2 0.0118 12-Jun R.EAYFWLR.Q sp|Q8TCJ2|STT3B_HUMAN 1 983.4865 1.05 6454 19821 2 983.487841 492.7505 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1 6.1 3710.8 - 941633 - - - 1.3615 - 1.164 0.346 - 161.5 1 2 0 0.0013 7 0 0 0 4.32E+06 4.13E+06 - - - 2.0773 0.999 230117_WJC_METTL3_WT_vs_EV_F01.19823.19823.2 0.00688 12-May R.EAYFWLR[166.11].Q sp|Q8TCJ2|STT3B_HUMAN 1 993.4948 1.07 6456 19823 2 993.497023 497.7547 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1 6.1 3710.9 - 922706 - - - 2.2657 - 1.31 0.368 - 126.5 1 2 0 0.0023 7 0 0 0 4.35E+06 4.04E+06 - - - 2.6139 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.19824.19824.2 0.0163 18-Sep R.TEVVSLLLDR.K "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1143.6499 2.17 6457 19824 2 1143.655128 572.8322 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 3711 - 902458 - - - 4.5372 - 2.063 0.373 - 289.6 1 2 0 0.0052 10 0 0 0 1.48E+07 6.80E+06 - - - 3.8157 0.9949 230117_WJC_METTL3_WT_vs_EV_F01.19825.19825.2 0.172 12-Jul K.LTFLDLR.N "sp|Q9H9A6|LRC40_HUMAN,tr|X6R5P2|X6R5P2_HUMAN" 2 876.5069 1.53 6458 19825 2 876.508227 439.2607 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.84 3711 - 525071 - - - 1.5105 - 1.422 0.109 - 196.3 1 2 0 0.0013 7 0 0 0 6.55E+06 4.28E+06 - - - 0.9612 0.993 230117_WJC_METTL3_WT_vs_EV_F01.19834.19834.2 0.325 16-Jul K.LQLSLADFR[166.11].R "sp|O00541|PESC_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 2 1071.5952 0.99 6465 19834 2 1071.599904 536.8049 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 5.84 3712.1 - 471888 - - - 4.3757 - 1.604 0.21 - 148.3 1 2 0 0.0047 9 0 0 0 1.62E+07 1.64E+07 - - - 1.9576 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.19835.19835.2 0.00619 16-Sep K.LQLSLADFR.R "sp|O00541|PESC_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 2 1061.5869 0.98 6466 19835 2 1061.591347 531.8007 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 5.84 3712.1 - 359149 - - - 4.1466 - 1.849 0.396 - 304.1 1 2 0 0.0044 9 0 0 0 1.61E+07 1.63E+07 - - - 3.7427 0.9969 230117_WJC_METTL3_WT_vs_EV_F01.19836.19836.2 0.134 14-Jun R.NYFGLFPR.V sp|Q8WUF5|IASPP_HUMAN 1 1012.5131 2.18 6467 19836 2 1012.513052 507.2638 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.75 3712.2 - 1.22E+06 - - - 0.001 - 1.104 0.316 - 141.2 1 2 0 0 8 0 0 0 1.17E+07 5.35E+06 - - - 1.6734 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.19837.19837.2 0.511 14-Aug K.DFLIPIGK.A "sp|P11177|ODPB_HUMAN,tr|F8WF02|F8WF02_HUMAN,tr|C9J634|C9J634_HUMAN" 3 901.5273 1.64 6468 19837 2 901.528173 451.7709 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 5.84 3712.2 - 870036 - - - 0.9639 - 1.663 0.26 - 273.7 1 2 0 0.0009 8 0 0 0 3.91E+07 2.38E+07 - - - 2.4951 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.19840.19840.2 2.49 14-Aug K.DFLIPIGK[136.11].A "sp|P11177|ODPB_HUMAN,tr|F8WF02|F8WF02_HUMAN,tr|C9J634|C9J634_HUMAN" 3 909.5415 1.97 6471 19840 2 909.54182 455.778 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 5.84 3712.4 - 613303 - - - 0.3474 - 1.652 0.157 - 271.9 1 2 0 0.0003 8 0 0 0 3.17E+07 1.61E+07 - - - 1.7145 1 230117_WJC_METTL3_WT_vs_EV_F01.19842.19842.2 0.00221 20-Nov R.VAQFLVIYAPR.R sp|Q9H2M9|RBGPR_HUMAN 1 1275.7339 1.71 6473 19842 2 1275.735429 638.8742 Rab3 GTPase-activating protein non-catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP2 PE=1 SV=1 8.72 3712.6 - 278021 - - - 1.1648 - 2.582 0.437 - 575.2 1 2 0 0.0015 11 0 0 0 3.44E+06 2.01E+06 - - - 4.8343 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.19843.19843.3 1.98E-05 13/40 R.MLIPYIEHWPR.A "sp|O75208|COQ9_HUMAN,tr|H3BPY0|H3BPY0_HUMAN,tr|H3BNT2|H3BNT2_HUMAN" 3 1453.754 2.1 6474 19843 3 1453.759296 485.592 "Ubiquinone biosynthesis protein COQ9, mitochondrial OS=Homo sapiens OX=9606 GN=COQ9 PE=1 SV=1" 6.5 3712.6 - 65633.9 - - - 3.6244 - 2.636 0.507 - 284.3 1 2 0 0.0053 11 0 0 0 3.15E+06 1.50E+06 - - - 6.9446 0.9949 230117_WJC_METTL3_WT_vs_EV_F01.19844.19844.2 0.000246 22-Oct K.QYPISLVLAPTR.E "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1356.7765 1.12 6475 19844 2 1356.785026 679.3955 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.75 3712.8 - 96331.9 - - - 6.2575 - 2.085 0.415 - 346.3 1 2 0 0.0085 12 0 0 0 1.86E+06 1.66E+06 - - - 4.0368 1 230117_WJC_METTL3_WT_vs_EV_F01.19845.19845.2 0.0143 13/24 K.LLC[160.03]DSVVLQPYLR.E "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN,tr|H0YBB4|H0YBB4_HUMAN" 3 1574.8491 3.02 6476 19845 2 1574.851501 788.4318 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.83 3712.9 - 0 - - - 1.5563 - 2.614 0.519 - 622.4 1 2 0 0.0025 13 0 0 0 2.37E+06 7.85E+05 - - - 5.3397 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19846.19846.2 0.000413 24-Nov K.IYVDDGLISLQVK.Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1461.8079 -1 6477 19846 2 1461.809094 731.9112 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3713 - 0 - - - 0.8195 - 2.189 0.436 - 291.1 1 2 0 0.0012 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2717 1 230117_WJC_METTL3_WT_vs_EV_F01.19847.19847.2 3.57E-06 24-Nov R.LGIGMDTC[160.03]VIPLR.H "sp|P49903|SPS1_HUMAN,tr|Q5T5U6|Q5T5U6_HUMAN" 2 1443.7578 2.45 6478 19847 2 1443.75998 722.8862 "Selenide, water dikinase 1 OS=Homo sapiens OX=9606 GN=SEPHS1 PE=1 SV=2" 5.83 3713.1 - 122257 - - - 1.5155 - 2.25 0.481 - 314.3 1 2 0 0.0022 13 0 0 0 1.34E+06 5.46E+05 - - - 4.6743 0.9227 230117_WJC_METTL3_WT_vs_EV_F01.19848.19848.2 0.263 24-Jun R.LGIGMDTC[160.03]VIPLR[166.11].H "sp|P49903|SPS1_HUMAN,tr|Q5T5U6|Q5T5U6_HUMAN" 2 1453.7661 -1 6479 19848 2 1453.763992 727.8903 "Selenide, water dikinase 1 OS=Homo sapiens OX=9606 GN=SEPHS1 PE=1 SV=2" 5.83 3713.3 - 0 - - - -1.4239 - 1.317 0.069 - 57.2 6 2 0 -0.0021 13 0 0 0 0.00E+00 0.00E+00 - - - -0.0909 0.9238 230117_WJC_METTL3_WT_vs_EV_F01.19852.19852.2 0.271 14-Sep L.IALALLAR.R sp|P43116|PE2R2_HUMAN 1 839.5593 999 6482 19852 2 839.560032 420.7869 Prostaglandin E2 receptor EP2 subtype OS=Homo sapiens OX=9606 GN=PTGER2 PE=1 SV=2 9.75 3713.7 - 2.74E+06 - - - 0.904 - 1.943 0.182 - 386.8 1 1 0 0.0008 8 0 0 0 5.30E+06 0.00E+00 - - - 2.3883 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.19856.19856.2 0.179 16-Aug R.VLLPVLLNK.N sp|O00186|STXB3_HUMAN 1 1007.6743 1.68 6486 19856 2 1007.676487 504.8444 Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2 8.72 3714.2 - 2.16E+06 - - - 2.1674 - 1.856 0.243 - 158.4 1 2 0 0.0022 9 0 0 0 5.74E+06 3.41E+06 - - - 2.6242 1 230117_WJC_METTL3_WT_vs_EV_F01.19858.19858.2 2.77E-06 16/28 R.VMAGALEGDIFIGPK.A "sp|P61163|ACTZ_HUMAN,sp|P42025|ACTY_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 4 1516.796 1.37 6488 19858 2 1516.79759 759.4053 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4.37 3714.4 - 1.98E+06 - - - 1.0806 - 2.917 0.576 - 833.6 1 2 0 0.0016 15 0 0 0 8.85E+06 6.44E+06 - - - 5.9268 1 230117_WJC_METTL3_WT_vs_EV_F01.19860.19860.2 5.28E-07 15/22 R.LPADTC[160.03]LLEFAR.L "sp|Q8NF37|PCAT1_HUMAN,tr|A0A0G2JQ62|A0A0G2JQ62_HUMAN,tr|A0A0G2JRI7|A0A0G2JRI7_HUMAN" 3 1404.7071 1.16 6490 19860 2 1404.709797 703.3608 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 4.37 3714.7 - 1.42E+06 - - - 1.8943 - 2.721 0.565 - 985.8 1 2 0 0.0027 12 0 0 0 3.77E+06 3.25E+06 - - - 5.8471 0.9958 230117_WJC_METTL3_WT_vs_EV_F01.19861.19861.2 2.72E-05 14-Sep R.NYFGLFPR[166.11].V sp|Q8WUF5|IASPP_HUMAN 1 1022.5213 1.91 6491 19861 2 1022.517891 512.2679 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.75 3714.8 - 1.37E+06 - - - -3.3545 - 1.763 0.411 - 253 1 2 0 -0.0034 8 0 0 0 1.18E+07 6.18E+06 - - - 3.7857 1 230117_WJC_METTL3_WT_vs_EV_F01.19863.19863.2 1.59E-08 13/26 R.IMGIPEEEQMGLLR.V sp|P35579|MYH9_HUMAN 1 1614.8109 1.52 6493 19863 2 1614.812344 808.4128 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3715.1 - 1.27E+06 - - - 0.8639 - 2.481 0.646 - 422 1 2 0 0.0014 14 0 0 0 5.49E+06 3.62E+06 - - - 6.0922 1 230117_WJC_METTL3_WT_vs_EV_F01.19864.19864.2 7.82E-06 13/24 K.IYVDDGLISLQVK[136.11].Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1469.8221 1.35 6494 19864 2 1469.824267 735.9183 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3715.2 - 1.27E+06 - - - 1.477 - 2.507 0.625 - 408.2 1 2 0 0.0022 13 0 0 0 5.15E+06 3.81E+06 - - - 6.0154 1 230117_WJC_METTL3_WT_vs_EV_F01.19866.19866.2 0.00117 13/22 R.LPADTC[160.03]LLEFAR[166.11].L "sp|Q8NF37|PCAT1_HUMAN,tr|A0A0G2JQ62|A0A0G2JQ62_HUMAN,tr|A0A0G2JRI7|A0A0G2JRI7_HUMAN" 3 1414.7154 1.16 6496 19866 2 1414.71729 708.365 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 4.37 3715.5 - 1.07E+06 - - - 1.3317 - 2.53 0.447 - 746.3 1 2 0 0.0019 12 0 0 0 3.77E+06 3.25E+06 - - - 4.7843 1 230117_WJC_METTL3_WT_vs_EV_F01.19867.19867.2 0.00471 20-Oct R.LFEAEAQDLFR.D sp|Q9H223|EHD4_HUMAN 1 1337.6616 2.36 6497 19867 2 1337.662415 669.8381 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3715.6 - 863946 - - - 0.6347 - 2.337 0.463 - 336.9 1 2 0 0.0008 11 0 0 0 1.73E+07 7.36E+06 - - - 4.7568 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19868.19868.2 0.000193 20-Dec K.NLIEMSELEIK.H sp|Q9Y5X3|SNX5_HUMAN 1 1317.685 10.97 6498 19868 2 1317.686241 659.8498 Sorting nexin-5 OS=Homo sapiens OX=9606 GN=SNX5 PE=1 SV=1 4.25 3715.7 - 845812 - - - 0.9388 - 2.272 0.45 - 455 1 2 0 0.0012 11 0 0 0 2.75E+06 2.51E+05 - - - 4.5844 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19872.19872.2 0.00118 16-Dec K.LFSNVLILK.S "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1045.6536 1.17 6501 19872 2 1045.654942 523.8341 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.75 3716.4 - 798622 - - - 1.314 - 1.807 0.402 - 316.4 1 2 0 0.0014 9 0 0 0 4.90E+06 4.19E+06 - - - 3.7215 0.999 230117_WJC_METTL3_WT_vs_EV_F01.19873.19873.2 0.223 12-Sep K.NFGIWLR[166.11].Y "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 914.5002 0.84 6502 19873 2 914.501683 458.2574 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 9.75 3716.4 - 5.99E+06 - - - 1.6304 - 1.688 0.236 - 407.1 1 2 0 0.0015 7 0 0 0 1.32E+08 1.58E+08 - - - 2.4425 0.9948 230117_WJC_METTL3_WT_vs_EV_F01.19874.19874.2 0.0644 18-Sep R.TLLLDGNPFR.V sp|Q9H9A6|LRC40_HUMAN 1 1144.6241 0.76 6503 19874 2 1144.620097 573.3193 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.5 3716.5 - 1.55E+06 - - - -3.4605 - 1.886 0.368 - 280.3 1 2 0 -0.004 10 0 0 0 1.15E+07 1.50E+07 - - - 3.5288 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.19875.19875.2 0.657 14-Aug K.LLILALER[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 949.62 1.29 6504 19875 2 949.621749 475.8173 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6 3716.6 - 1.35E+06 - - - 1.8702 - 1.721 0.133 - 219.8 1 2 0 0.0018 8 0 0 0 3.44E+07 2.67E+07 - - - 1.6602 1 230117_WJC_METTL3_WT_vs_EV_F01.19876.19876.2 0.0317 20-Nov R.LFEAEAQDLFR[166.11].D sp|Q9H223|EHD4_HUMAN 1 1347.6698 2.36 6505 19876 2 1347.67082 674.8422 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3716.8 - 964514 - - - 0.7301 - 2.358 0.509 - 392.2 1 2 0 0.001 11 0 0 0 1.73E+07 7.36E+06 - - - 5.1208 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19878.19878.2 4.06E-06 18-Sep R.C[160.03]LFQSPLFAK[136.11].A sp|Q86X55|CARM1_HUMAN 1 1217.6358 1.53 6507 19878 2 1217.635802 609.8252 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 8.22 3717 - 877699 - - - -0.0115 - 1.843 0.441 - 209.6 1 2 0 0 10 0 0 0 5.47E+06 3.59E+06 - - - 4.0048 0.8667 230117_WJC_METTL3_WT_vs_EV_F01.19879.19879.2 0.0596 16-Jul K.EAVWAVTNY.T "sp|P52292|IMA1_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 4 1051.4975 - 6508 19879 2 1051.499262 526.756 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 4 3717.1 - 790411 - - - 1.7128 - 1.132 0.322 - 101.5 1 1 0 0.0018 9 0 0 0 - - - - - 1.7774 1 230117_WJC_METTL3_WT_vs_EV_F01.19880.19880.2 4.03E-10 16/24 K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 0.28 6509 19880 2 1600.746236 801.3794 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3717.3 - 643517 - - - 1.2032 - 2.745 0.661 - 694.4 1 2 0 0.0019 13 0 0 0 4.56E+06 1.61E+07 - - - 6.5142 1 230117_WJC_METTL3_WT_vs_EV_F01.19881.19881.2 0.000132 18-Dec K.LLDEVFFSEK.L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1225.6231 1.62 6510 19881 2 1225.624421 613.8188 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3717.4 - 516347 - - - 1.1145 - 2.372 0.429 - 402.1 1 2 0 0.0014 10 0 0 0 1.74E+08 1.07E+08 - - - 4.6201 0.9151 230117_WJC_METTL3_WT_vs_EV_F01.19882.19882.2 0.00499 18-Aug G.MEELIPLVNK.L sp|P50570|DYN2_HUMAN 1 1184.6475 1.04 6511 19882 2 1184.648326 593.331 Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2 4.53 3717.5 - 468572 - - - 0.7006 - 1.584 0.27 - 152.6 1 1 0 0.0008 10 0 0 0 2.94E+06 2.83E+06 - - - 2.3188 0.8653 230117_WJC_METTL3_WT_vs_EV_F01.19883.19883.2 0.0577 14/20 R.PTTFAIIENLK[136.11].Y sp|Q96EU7|C1GLC_HUMAN 1 1253.7111 0.82 6512 19883 2 1253.711546 627.8628 C1GALT1-specific chaperone 1 OS=Homo sapiens OX=9606 GN=C1GALT1C1 PE=1 SV=1 6.43 3717.7 - 420278 - - - 0.3645 - 1.266 0.305 - 187.8 1 1 0 0.0005 11 0 0 0 2.13E+06 2.58E+06 - - - 1.9316 0.942 230117_WJC_METTL3_WT_vs_EV_F01.19885.19885.2 0.14 18-Jul R.FPPVVFYTPK.E "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1193.6485 4.96 6514 19885 2 1193.65638 597.8315 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3717.9 - 360587 - - - 6.6167 - 1.348 0.223 - 88 2 2 0 0.0079 10 0 0 0 1.98E+06 3.98E+05 - - - 1.3847 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.19886.19886.2 1.99 14-Aug K.SLLAGLLK[136.11].K "sp|P31751|AKT2_HUMAN,tr|M0R0P9|M0R0P9_HUMAN,tr|J3QKW1|J3QKW1_HUMAN,tr|J3QL45|J3QL45_HUMAN,tr|M0R283|M0R283_HUMAN,tr|M0QZW8|M0QZW8_HUMAN" 6 821.5466 0.8 6515 19886 2 821.547424 411.7806 RAC-beta serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=AKT2 PE=1 SV=2 8.47 3718.1 - 340138 - - - 1.0152 - 1.562 0.252 - 205.1 1 2 0 0.0008 8 0 0 0 2.25E+06 2.82E+06 - - - 2.247 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.19888.19888.2 0.0554 14-Sep K.SVWALLQR[166.11].N sp|Q5VUD6|DIK1B_HUMAN 1 981.5635 1.25 6517 19888 2 981.565974 491.789 Divergent protein kinase domain 1B OS=Homo sapiens OX=9606 GN=DIPK1B PE=1 SV=3 9.47 3718.3 - 314172 - - - 2.5001 - 1.492 0.224 - 236 1 2 0 0.0025 8 0 0 0 2.76E+06 2.21E+06 - - - 1.9014 1 230117_WJC_METTL3_WT_vs_EV_F01.19894.19894.2 8.13E-05 18-Nov K.LLDEVFFSEK[136.11].L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1233.6373 1.62 6522 19894 2 1233.638754 617.8259 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3718.9 - 1.44E+07 - - - 1.2151 - 2.266 0.471 - 304.9 1 2 0 0.0015 10 0 0 0 1.74E+08 1.07E+08 - - - 4.8027 1 230117_WJC_METTL3_WT_vs_EV_F01.19895.19895.2 5.51E-06 15/22 R.IYGLGSLALYEK.A sp|P36542|ATPG_HUMAN 1 1325.7231 1.6 6523 19895 2 1325.724945 663.8688 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6 3719 - 1.34E+07 - - - 1.3887 - 2.777 0.535 - 682.7 1 2 0 0.0018 12 0 0 0 2.73E+08 1.70E+08 - - - 5.6793 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.19896.19896.2 0.0154 18-Aug R.TLLLDGNPFR[166.11].V sp|Q9H9A6|LRC40_HUMAN 1 1154.6323 0.76 6524 19896 2 1154.631784 578.3234 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.5 3719 - 5.31E+06 - - - -0.4711 - 1.538 0.259 - 200.7 1 2 0 -0.0005 10 0 0 0 1.15E+07 1.52E+07 - - - 2.1554 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.19897.19897.3 7.79E-05 17/68 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 2.58 6525 19897 3 1918.067537 640.3618 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3719.1 - 4.77E+06 - - - 2.0474 - 2.48 0.415 - 189.6 1 2 0 0.0039 18 0 0 0 1.48E+07 5.72E+06 - - - 5.4274 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19899.19899.2 0.00338 16-Aug K.VIPTLALLK.D sp|O14530|TXND9_HUMAN 1 966.6478 2.18 6527 19899 2 966.648799 484.3312 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 8.72 3719.2 - 3.97E+06 - - - 1.0811 - 1.312 0.386 - 143.6 1 2 0 0.001 9 0 0 0 7.92E+06 3.63E+06 - - - 2.6773 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19903.19903.2 0.00398 16-Sep K.TLFPLIEAK[136.11].K sp|P13010|XRCC5_HUMAN 1 1038.6205 1.03 6531 19903 2 1038.623063 520.3175 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.66 3719.4 - 2.91E+06 - - - 2.4841 - 1.551 0.375 - 240 1 2 0 0.0026 9 0 0 0 4.38E+08 4.25E+08 - - - 3.0797 0.9854 230117_WJC_METTL3_WT_vs_EV_F01.19904.19904.2 0.0152 14-Sep R.NLFEQLVR[166.11].R "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VV47|F8VV47_HUMAN,tr|F8VUW9|F8VUW9_HUMAN,tr|F8VWY4|F8VWY4_HUMAN,tr|F8VRD2|F8VRD2_HUMAN,tr|F8VVY0|F8VVY0_HUMAN,tr|F8VZ66|F8VZ66_HUMAN,tr|F8VWX0|F8VWX0_HUMAN,tr|F8VS54|F8VS54_HUMAN,tr|F8W0L1|F8W0L1_HUMAN,tr|F8VVE5|F8VVE5_HUMAN,tr|F8VV39|F8VV39_HUMAN,tr|F8VXH1|F8VXH1_HUMAN" 13 1027.569 2.25 6532 19904 2 1027.576128 514.7918 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 6 3719.5 - 2.87E+06 - - - 6.9368 - 1.685 0.324 - 298.9 1 2 0 0.0071 8 0 0 0 1.25E+07 5.57E+06 - - - 3.0054 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19905.19905.2 0.000671 18-Oct R.C[160.03]LFQSPLFAK.A sp|Q86X55|CARM1_HUMAN 1 1209.6216 1.47 6533 19905 2 1209.624943 605.8181 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 8.22 3719.6 - 2.69E+06 - - - 2.7504 - 1.457 0.433 - 276.4 1 2 0 0.0033 10 0 0 0 5.28E+06 3.59E+06 - - - 3.2887 1 230117_WJC_METTL3_WT_vs_EV_F01.19906.19906.2 3.49E-05 13/20 R.EVWALVQAGIR.D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1240.6928 1.47 6534 19906 2 1240.694122 621.3537 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.1 3719.6 - 2.62E+06 - - - 1.0599 - 2.448 0.516 - 688.4 1 2 0 0.0013 11 0 0 0 1.08E+07 7.33E+06 - - - 5.2737 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19911.19911.2 1.76E-05 20-Sep R.EYIDYEFSVLK.E "sp|Q8IZH2|XRN1_HUMAN,tr|C9JCZ8|C9JCZ8_HUMAN" 2 1404.6813 -1 6539 19911 2 1404.67976 703.3479 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.14 3720.2 - 1.15E+06 - - - -1.0956 - 1.934 0.476 - 239.5 1 2 0 -0.0015 11 0 0 0 0.00E+00 0.00E+00 - - - 4.3406 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19915.19915.2 0.00913 14-Sep K.IPDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1069.5584 1.26 6542 19915 2 1069.560479 535.7865 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3720.5 - 4.44E+06 - - - 1.9111 - 1.741 0.371 - 415.5 1 2 0 0.002 8 0 0 0 7.53E+09 5.99E+09 - - - 3.4528 0.9751 230117_WJC_METTL3_WT_vs_EV_F01.19916.19916.2 1.91E-05 16-Jul K.VYFLPITPH.Y "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1085.591 - 6543 19916 2 1085.593421 543.8028 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6.71 3720.6 - 3.03E+06 - - - 2.2605 - 1.78 0.509 - 243.5 1 1 0 0.0025 9 0 0 0 - - - - - 4.4679 1 230117_WJC_METTL3_WT_vs_EV_F01.19917.19917.2 5.44E-07 14/22 R.IYGLGSLALYEK[136.11].A sp|P36542|ATPG_HUMAN 1 1333.7373 1.6 6544 19917 2 1333.739873 667.8759 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6 3720.6 - 2.70E+06 - - - 1.9262 - 2.781 0.544 - 584 1 2 0 0.0026 12 0 0 0 2.73E+08 1.70E+08 - - - 5.7494 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19919.19919.2 0.00652 18-Sep K.SVLIGEFLEK[136.11].V "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1141.6474 0.93 6546 19919 2 1141.648832 571.831 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 3720.8 - 1.04E+06 - - - 1.2316 - 1.925 0.449 - 275.3 1 2 0 0.0014 10 0 0 0 1.35E+08 1.46E+08 - - - 4.185 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19920.19920.2 0.00894 18-Sep K.SVLIGEFLEK.V "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1133.6332 0.93 6547 19920 2 1133.634539 567.8239 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 3720.9 - 735593 - - - 1.1582 - 2.02 0.43 - 273 1 2 0 0.0013 10 0 0 0 1.35E+08 1.46E+08 - - - 4.1791 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19925.19925.2 0.000477 20-Aug R.EYIDYEFSVLK[136.11].E "sp|Q8IZH2|XRN1_HUMAN,tr|C9JCZ8|C9JCZ8_HUMAN" 2 1412.6955 1.65 6552 19925 2 1412.699023 707.355 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.14 3721.5 - 111744 - - - 2.4945 - 1.59 0.375 - 178.1 1 2 0 0.0035 11 0 0 0 2.28E+06 1.38E+06 - - - 3.0642 1 230117_WJC_METTL3_WT_vs_EV_F01.19929.19929.2 3.88E-08 15/22 K.ALEDAFLAIDAK.L sp|O15355|PPM1G_HUMAN 1 1275.6711 2.9 6554 19929 2 1275.672949 638.8428 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.03 3722 - 3.19E+06 - - - 1.4745 - 2.691 0.57 - 683.1 1 2 0 0.0019 12 0 0 0 2.60E+07 8.98E+06 - - - 5.8551 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19930.19930.2 0.00162 18-Sep K.ELLGQGLLLR[166.11].S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1120.6844 0.92 6555 19930 2 1120.686406 561.3495 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3722.1 - 2.64E+06 - - - 1.8221 - 1.998 0.35 - 294 1 2 0 0.002 10 0 0 0 1.41E+08 1.53E+08 - - - 3.5575 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19931.19931.2 0.00218 18-Oct R.GPILLPYQFR[166.11].M "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1212.6894 1.09 6556 19931 2 1212.692227 607.352 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 8.75 3722.2 - 1.36E+06 - - - 2.2908 - 2.251 0.409 - 377.7 1 2 0 0.0028 10 0 0 0 1.79E+07 1.64E+07 - - - 4.3258 0.997 230117_WJC_METTL3_WT_vs_EV_F01.19932.19932.2 2.62E-05 18-Oct R.GPILLPYQFR.M "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1202.6812 1.09 6557 19932 2 1202.687914 602.3479 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 8.75 3722.2 - 1.28E+06 - - - 5.6 - 2.026 0.432 - 436.8 1 2 0 0.0067 10 0 0 0 1.79E+07 1.64E+07 - - - 4.2005 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19933.19933.2 0.157 18-Nov R.VDLPLAVLSK.M "sp|Q9H773|DCTP1_HUMAN,tr|H3BSA6|H3BSA6_HUMAN" 2 1053.6434 11.8 6558 19933 2 1053.644161 527.829 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 5.81 3722.3 - 1.14E+06 - - - 0.7251 - 2.218 0.393 - 290.3 1 2 0 0.0008 10 0 0 0 4.75E+07 4.03E+06 - - - 4.167 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.19938.19938.2 0.00742 22-Dec R.TFLESPLDVGIK.L "sp|Q8TEU7|RPGF6_HUMAN,tr|B7Z7Y1|B7Z7Y1_HUMAN,tr|E9PCH4|E9PCH4_HUMAN,tr|D6RE77|D6RE77_HUMAN,tr|A0A5F9ZHG7|A0A5F9ZHG7_HUMAN" 5 1317.718 0.12 6563 19938 2 1317.722935 659.8663 Rap guanine nucleotide exchange factor 6 OS=Homo sapiens OX=9606 GN=RAPGEF6 PE=1 SV=2 4.37 3723 - 355809 - - - 3.7315 - 2.478 0.402 - 396.8 1 2 0 0.0049 12 0 0 0 3.24E+07 2.65E+08 - - - 4.3963 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19944.19944.2 0.0224 13/22 K.LANILFTQELAR.R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1387.7823 1.42 6567 19944 2 1387.78175 694.8985 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3723.7 - 1.88E+06 - - - -0.4323 - 2.968 0.274 - 719 1 2 0 -0.0006 12 0 0 0 3.26E+07 2.29E+07 - - - 3.927 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19945.19945.2 0.0346 16/22 K.LANILFTQELAR[166.11].R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1397.7906 1.4 6568 19945 2 1397.791164 699.9026 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3723.9 - 1.85E+06 - - - 0.3892 - 2.631 0.296 - 1214.5 1 2 0 0.0005 12 0 0 0 3.20E+07 2.29E+07 - - - 3.7724 0.999 230117_WJC_METTL3_WT_vs_EV_F01.19946.19946.2 0.0376 18-Sep K.ELLGQGLLLR.S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1110.6761 0.92 6569 19946 2 1110.677849 556.3453 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3723.9 - 1.01E+07 - - - 1.5801 - 1.758 0.248 - 309 1 2 0 0.0018 10 0 0 0 1.41E+08 1.53E+08 - - - 2.447 0.9525 230117_WJC_METTL3_WT_vs_EV_F01.19949.19949.2 0.00601 14-Jul F.GPILNFLR.H "sp|Q8N5Z5|KCD17_HUMAN,tr|H7C323|H7C323_HUMAN,tr|B0QYB2|B0QYB2_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 5 928.5494 0.56 6572 19949 2 928.550047 465.282 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 9.75 3724.2 - 1.43E+06 - - - 0.6569 - 1.717 0.323 - 203.9 1 1 0 0.0006 8 0 0 0 1.60E+07 2.86E+07 - - - 3.0568 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19950.19950.2 0.000744 18-Aug K.QLEDILVLAK[136.11].Q "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A0A6YYJ5|A0A0A6YYJ5_HUMAN" 8 1148.6896 2.66 6573 19950 2 1148.69115 575.3521 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.37 3724.3 - 854120 - - - 1.3276 - 1.769 0.341 - 136.8 1 2 0 0.0015 10 0 0 0 1.35E+07 5.06E+06 - - - 3.1513 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.19951.19951.2 0.0176 20-Aug K.IESLPPLLIGK[136.11].F "sp|Q8N9N7|LRC57_HUMAN,tr|A0A3B3ISV5|A0A3B3ISV5_HUMAN,tr|H3BSW0|H3BSW0_HUMAN" 3 1186.7417 2.38 6574 19951 2 1186.743168 594.3781 Leucine-rich repeat-containing protein 57 OS=Homo sapiens OX=9606 GN=LRRC57 PE=1 SV=1 6 3724.4 - 745136 - - - 1.2699 - 1.366 0.354 - 138.1 1 2 0 0.0015 11 0 0 0 9.19E+06 3.86E+06 - - - 2.4989 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.19952.19952.2 0.11 12-May K.DAFLVFR.S "sp|Q9Y6D6|BIG1_HUMAN,sp|Q9Y6D5|BIG2_HUMAN,tr|A0A7P0T7Z2|A0A7P0T7Z2_HUMAN,tr|A0A7P0T9L9|A0A7P0T9L9_HUMAN,tr|A0A7P0TA34|A0A7P0TA34_HUMAN,tr|A0A7P0T9L6|A0A7P0T9L6_HUMAN" 6 866.465 1.46 6575 19952 2 866.466036 434.2398 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens OX=9606 GN=ARFGEF1 PE=1 SV=2 5.84 3724.6 - 728242 - - - 1.1518 - 1.169 0.222 - 68.5 1 2 0 0.001 7 0 0 0 5.10E+06 3.48E+06 - - - 1.1751 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.19953.19953.2 0.00854 12-Jul K.DAFLVFR[166.11].S "sp|Q9Y6D6|BIG1_HUMAN,sp|Q9Y6D5|BIG2_HUMAN,tr|A0A7P0T7Z2|A0A7P0T7Z2_HUMAN,tr|A0A7P0T9L9|A0A7P0T9L9_HUMAN,tr|A0A7P0TA34|A0A7P0TA34_HUMAN,tr|A0A7P0T9L6|A0A7P0T9L6_HUMAN" 6 876.4733 1.46 6576 19953 2 876.47638 439.2439 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens OX=9606 GN=ARFGEF1 PE=1 SV=2 5.84 3724.7 - 471403 - - - 3.505 - 1.57 0.323 - 202.9 1 2 0 0.0031 7 0 0 0 5.10E+06 3.48E+06 - - - 2.855 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.19954.19954.2 0.0409 20-Oct K.ALLLSSVLSEK[136.11].G "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1166.7002 3.11 6577 19954 2 1166.704555 584.3574 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 6.05 3724.8 - 464718 - - - 3.7413 - 2.227 0.307 - 246.5 1 2 0 0.0044 11 0 0 0 1.37E+07 4.40E+06 - - - 3.4731 0.9611 230117_WJC_METTL3_WT_vs_EV_F01.19958.19958.2 0.0267 12-Aug L.PDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 946.4661 1.32 6579 19958 2 946.46614 474.2403 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 6.27 3725.4 - 2.95E+06 - - - 0.0412 - 1.814 0.387 - 281.3 1 1 0 0 7 0 0 0 4.87E+07 3.69E+07 - - - 3.7864 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.19959.19959.2 0.000443 20-Nov K.ALLLSSVLSEK.G "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1158.686 3.11 6580 19959 2 1158.685517 580.3503 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 6.05 3725.5 - 1.96E+06 - - - -0.4082 - 2.337 0.377 - 393.9 1 2 0 -0.0005 11 0 0 0 1.37E+07 4.40E+06 - - - 4.1218 1 230117_WJC_METTL3_WT_vs_EV_F01.19965.19965.2 2.05E-05 20-Sep K.SFYGSTLFLC[160.03]R.R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1349.6438 1.17 6586 19965 2 1349.636731 675.8292 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 7.94 3726.2 - 484317 - - - -5.2436 - 1.885 0.527 - 257.1 1 2 0 -0.0071 11 0 0 0 1.05E+07 8.96E+06 - - - 4.6461 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.19970.19970.2 0.00118 14-Sep K.IPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1059.5502 1.26 6590 19970 2 1059.552075 530.7824 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3726.8 - 5.34E+08 - - - 1.8027 - 1.792 0.48 - 492.9 1 2 0 0.0019 8 0 0 0 7.53E+09 5.99E+09 - - - 4.345 1 230117_WJC_METTL3_WT_vs_EV_F01.19974.19974.2 9.75E-08 14/22 K.IYDALDVSLIER.G sp|P54136|SYRC_HUMAN 1 1405.7453 1.56 6593 19974 2 1405.743696 703.8799 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.03 3727.2 - 1.67E+06 - - - -1.1382 - 2.773 0.607 - 856.4 1 2 0 -0.0016 12 0 0 0 3.04E+07 1.94E+07 - - - 6.2074 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19975.19975.2 0.00327 16-Aug R.ILDTLGLLR.Q "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN,tr|A0A087WWF4|A0A087WWF4_HUMAN" 3 1012.6281 1.21 6594 19975 2 1012.629956 507.3213 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 5.84 3727.2 - 1.40E+06 - - - 1.8516 - 1.944 0.384 - 139.5 1 2 0 0.0019 9 0 0 0 1.72E+07 1.42E+07 - - - 3.7998 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19978.19978.2 0.0121 14-Sep R.MGLLAVLR.S "sp|O95394|AGM1_HUMAN,tr|D6RF77|D6RF77_HUMAN,tr|D6RC77|D6RC77_HUMAN,tr|D6RCQ8|D6RCQ8_HUMAN,tr|A0A494C099|A0A494C099_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C163|A0A494C163_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|D6RCD1|D6RCD1_HUMAN" 9 871.5313 1.69 6597 19978 2 871.53301 436.7729 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 9.5 3727.5 - 556669 - - - 1.9116 - 2.008 0.375 - 300.1 1 2 0 0.0017 8 0 0 0 5.46E+06 3.22E+06 - - - 3.9128 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.19982.19982.2 0.121 14-Aug R.LSLELFGR.V "sp|O95071|UBR5_HUMAN,tr|E5RFK7|E5RFK7_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 933.5284 1.69 6600 19982 2 933.528117 467.7715 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 6 3727.9 - 1.39E+06 - - - -0.2678 - 1.629 0.263 - 178 1 2 0 -0.0003 8 0 0 0 2.44E+07 1.45E+07 - - - 2.4551 1 230117_WJC_METTL3_WT_vs_EV_F01.19984.19984.2 8.51E-05 13/22 K.IYDALDVSLIER[166.11].G sp|P54136|SYRC_HUMAN 1 1415.7536 1.56 6602 19984 2 1415.753441 708.8841 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.03 3728.2 - 693000 - - - -0.0883 - 2.665 0.542 - 663.8 1 2 0 -0.0001 12 0 0 0 3.04E+07 1.94E+07 - - - 5.6233 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.19985.19985.2 8.27E-05 20-Oct K.SFYGSTLFLC[160.03]R[166.11].R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1359.6521 1.17 6603 19985 2 1359.656718 680.8333 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 7.94 3728.3 - 336853 - - - 3.4126 - 1.872 0.481 - 342.6 1 2 0 0.0046 11 0 0 0 1.05E+07 8.96E+06 - - - 4.2884 0.9542 230117_WJC_METTL3_WT_vs_EV_F01.19991.19991.2 0.0355 12-Aug L.PDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 956.4744 1.98 6607 19991 2 956.47428 479.2445 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 6.27 3729.1 - 1.70E+06 - - - -0.0951 - 1.787 0.37 - 267.7 1 1 0 -0.0001 7 0 0 0 7.38E+07 3.73E+07 - - - 3.6133 0.9938 230117_WJC_METTL3_WT_vs_EV_F01.19995.19995.2 0.00773 18-Jul R.LVLVNAVYFR.G "sp|P35237|SPB6_HUMAN,tr|A0A087X1N8|A0A087X1N8_HUMAN,tr|A0A2R8Y6A7|A0A2R8Y6A7_HUMAN,tr|A0A024QZX5|A0A024QZX5_HUMAN,tr|A0A2R8YD12|A0A2R8YD12_HUMAN" 5 1192.6968 0.64 6611 19995 2 1192.703614 597.3557 Serpin B6 OS=Homo sapiens OX=9606 GN=SERPINB6 PE=1 SV=3 8.75 3729.6 - 442122 - - - 5.6888 - 1.806 0.324 - 120.7 1 2 0 0.0068 10 0 0 0 7.78E+06 1.21E+07 - - - 3.0819 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.19996.19996.2 0.000313 18-Oct K.GIYLWDVEGR[166.11].K sp|P04181|OAT_HUMAN 1 1216.6116 1.44 6612 19996 2 1216.611897 609.3131 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.37 3729.7 - 432114 - - - 0.2499 - 1.956 0.442 - 347 1 2 0 0.0003 10 0 0 0 9.37E+06 6.52E+06 - - - 4.1782 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.19997.19997.2 0.00899 20-Nov K.IFTMAEVYGIR[166.11].T sp|Q96P70|IPO9_HUMAN 1 1308.6776 0.71 6613 19997 2 1308.67704 655.3461 Importin-9 OS=Homo sapiens OX=9606 GN=IPO9 PE=1 SV=3 6 3729.8 - 314215 - - - -0.4004 - 2.307 0.405 - 357.5 1 2 0 -0.0005 11 0 0 0 4.05E+06 5.68E+06 - - - 4.2936 1 230117_WJC_METTL3_WT_vs_EV_F01.20002.20002.2 0.000171 13/24 R.LLLFSSATDAAIR.V "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1376.7664 0.37 6616 20002 2 1376.765887 689.3905 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.84 3730.5 - 208229 - - - -0.3479 - 2.65 0.547 - 623.9 1 2 0 -0.0005 13 0 0 0 7.76E+06 2.10E+07 - - - 5.5822 1 230117_WJC_METTL3_WT_vs_EV_F01.20003.20003.2 2.35E-05 18-Oct K.GIYLWDVEGR.K sp|P04181|OAT_HUMAN 1 1206.6033 1.42 6617 20003 2 1206.599839 604.3089 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.37 3730.7 - 229885 - - - -2.8874 - 1.996 0.496 - 342.9 1 2 0 -0.0035 10 0 0 0 9.70E+06 6.80E+06 - - - 4.6326 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.20004.20004.2 0.0117 20-Dec R.ASEAVLWEALR.K "sp|Q9Y5V3|MAGD1_HUMAN,sp|Q96JG8|MAGD4_HUMAN" 2 1243.6561 44.83 6618 20004 2 1243.654463 622.8353 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 4.53 3730.8 - 195379 - - - -1.3058 - 1.819 0.295 - 390.8 1 2 0 -0.0016 11 0 0 0 6.76E+06 1.51E+05 - - - 2.8379 1 230117_WJC_METTL3_WT_vs_EV_F01.20005.20005.2 0.00138 13/20 R.NAVLAIYTIYR[166.11].N "sp|P53618|COPB_HUMAN,tr|E9PP73|E9PP73_HUMAN" 2 1305.732 3.16 6619 20005 2 1305.731556 653.8733 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 8.59 3730.9 - 0 - - - -0.3722 - 2.612 0.403 - 706.3 1 2 0 -0.0005 11 0 0 0 3.68E+07 1.16E+07 - - - 4.6147 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.20012.20012.2 0.0111 18-Aug K.IINFAPSLLR.L "sp|O15397|IPO8_HUMAN,tr|F5H2I3|F5H2I3_HUMAN" 2 1142.6812 1.29 6623 20012 2 1142.68589 572.3479 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 9.75 3731.6 - 566996 - - - 4.1228 - 2.067 0.409 - 179.4 1 2 0 0.0047 10 0 0 0 4.54E+07 3.52E+07 - - - 4.0872 0.9945 230117_WJC_METTL3_WT_vs_EV_F01.20013.20013.2 0.34 14-May R.SLPVFPFR.E "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 961.5385 1.42 6624 20013 2 961.54039 481.7765 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 9.47 3731.8 - 501490 - - - 1.9261 - 1.105 0.22 - 88.8 1 2 0 0.0019 8 0 0 0 1.37E+07 9.64E+06 - - - 0.9665 1 230117_WJC_METTL3_WT_vs_EV_F01.20015.20015.2 0.000151 20-Oct K.IFTMAEVYGIR.T sp|Q96P70|IPO9_HUMAN 1 1298.6693 0.79 6626 20015 2 1298.671906 650.3419 Importin-9 OS=Homo sapiens OX=9606 GN=IPO9 PE=1 SV=3 6 3732 - 202545 - - - 2.0113 - 2.142 0.473 - 294.4 1 2 0 0.0026 11 0 0 0 5.51E+06 6.97E+06 - - - 4.5944 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20016.20016.2 0.000132 24-Oct R.VETPVLPPVLVPR[166.11].H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1424.8631 2.18 6627 20016 2 1424.864926 713.4388 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3732.1 - 0 - - - 1.3117 - 1.788 0.412 - 244.5 1 2 0 0.0019 13 0 0 0 1.95E+07 8.94E+06 - - - 3.5748 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.20018.20018.2 0.073 28-Jul R.LTPSASLPPAQLLLR.A "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 1575.9348 -1 6629 20018 2 1575.935077 788.9747 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 9.75 3732.4 - 0 - - - 0.158 - 1.127 0.293 - 100.6 1 2 0 0.0002 15 0 0 0 0.00E+00 0.00E+00 - - - 1.499 0.9674 230117_WJC_METTL3_WT_vs_EV_F01.20021.20021.2 0.778 12-Jul K.LLDDLFR[166.11].K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 900.4944 1 6630 20021 2 900.492813 451.2545 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3732.8 - 753932 - - - -1.8046 - 1.364 0.09 - 126.9 1 2 0 -0.0016 7 0 0 0 1.89E+08 1.90E+08 - - - 0.6888 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.20022.20022.3 0.0643 Nov-40 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 23.61 6631 20022 3 1276.704681 426.5748 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3732.9 - 229957 - - - 1.5493 - 1.934 0.132 - 287.6 1 2 0 0.002 11 0 0 0 1.37E+07 5.79E+05 - - - 1.8849 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20023.20023.2 0.0233 18-Sep K.IINFAPSLLR[166.11].L "sp|O15397|IPO8_HUMAN,tr|F5H2I3|F5H2I3_HUMAN" 2 1152.6894 1.29 6632 20023 2 1152.691465 577.352 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 9.75 3733 - 982940 - - - 1.749 - 2.076 0.383 - 248.2 1 2 0 0.002 10 0 0 0 4.54E+07 3.52E+07 - - - 3.9081 0.9928 230117_WJC_METTL3_WT_vs_EV_F01.20024.20024.2 0.0963 18-Jul R.AAFVLPEFAR.K "sp|P19623|SPEE_HUMAN,tr|K7EL89|K7EL89_HUMAN" 2 1119.6077 5.52 6633 20024 2 1119.605243 560.8111 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 6.05 3733.1 - 647341 - - - -2.1767 - 1.51 0.266 - 101.2 1 2 0 -0.0024 10 0 0 0 5.77E+07 1.05E+07 - - - 2.1552 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.20028.20028.2 0.0115 14-Oct R.NLIEWLNK[136.11].Y sp|Q96DG6|CMBL_HUMAN 1 1036.5797 0.88 6635 20028 2 1036.580409 519.2971 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 6 3733.6 - 4.64E+06 - - - 0.7023 - 1.808 0.266 - 329 1 2 0 0.0007 8 0 0 0 1.35E+08 1.53E+08 - - - 2.7916 0.9954 230117_WJC_METTL3_WT_vs_EV_F01.20029.20029.2 0.0943 12-Jul R.WLSQYID.- "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 923.4389 - 6636 20029 2 923.439493 462.7267 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.3 3733.7 - 1.52E+06 - - - 0.6606 - 1.147 0.222 - 114.1 1 2 0 0.0006 7 0 0 0 - - - - - 1.1151 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.20030.20030.2 0.539 12-Sep K.LLDDLFR.K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 890.4862 0.99 6637 20030 2 890.486324 446.2504 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3733.8 - 2.75E+06 - - - 0.1752 - 1.382 0.205 - 250.9 1 2 0 0.0002 7 0 0 0 1.91E+08 1.93E+08 - - - 1.5802 1 230117_WJC_METTL3_WT_vs_EV_F01.20031.20031.2 9.72E-06 18-Dec R.SPVTFLSDLR.S sp|A5YKK6|CNOT1_HUMAN 1 1133.6081 2.34 6638 20031 2 1133.603707 567.8113 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 5.55 3733.9 - 710382 - - - -3.8523 - 2.539 0.499 - 523.2 1 2 0 -0.0044 10 0 0 0 7.64E+06 3.26E+06 - - - 5.3261 1 230117_WJC_METTL3_WT_vs_EV_F01.20032.20032.2 1.83E-09 14/20 R.WGAFAQSILER[166.11].G sp|Q13472|TOP3A_HUMAN 1 1286.6647 0.01 6639 20032 2 1286.65745 644.3396 DNA topoisomerase 3-alpha OS=Homo sapiens OX=9606 GN=TOP3A PE=1 SV=1 6 3734.1 - 653666 - - - -5.6277 - 2.929 0.624 - 874.8 1 2 0 -0.0072 11 0 0 0 1.55E+05 1.12E+07 - - - 6.5548 0.993 230117_WJC_METTL3_WT_vs_EV_F01.20034.20034.2 2.86E-05 18-Oct R.LNDYIFSFDK.M sp|P54136|SYRC_HUMAN 1 1260.6027 1.69 6641 20034 2 1260.59682 631.3086 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.21 3734.3 - 473323 - - - -4.6279 - 2.128 0.445 - 464.5 1 2 0 -0.0058 10 0 0 0 7.40E+06 4.37E+06 - - - 4.4339 0.9852 230117_WJC_METTL3_WT_vs_EV_F01.20035.20035.2 0.000187 18-Oct R.LNDYIFSFDK[136.11].M sp|P54136|SYRC_HUMAN 1 1268.6169 1.69 6642 20035 2 1268.60944 635.3157 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.21 3734.4 - 465193 - - - -5.8442 - 2.131 0.446 - 500.1 1 2 0 -0.0074 10 0 0 0 7.40E+06 4.37E+06 - - - 4.4447 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.20037.20037.2 0.0165 14-Jul K.LDGFPLLR[166.11].R "sp|P09661|RU2A_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 2 939.5417 1.1 6644 20037 2 939.543427 470.7781 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 5.84 3734.7 - 334276 - - - 1.8147 - 1.718 0.257 - 123.1 1 2 0 0.0017 8 0 0 0 4.49E+06 4.08E+06 - - - 2.5708 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20039.20039.2 0.00286 20-Sep K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 127.48 6645 20039 2 1276.703095 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3734.9 - 2.85E+07 - - - 0.307 - 2.008 0.384 - 395.2 1 2 0 0.0004 11 0 0 0 1.26E+09 9.92E+06 - - - 3.763 1 230117_WJC_METTL3_WT_vs_EV_F01.20042.20042.2 1.00E-09 13/26 K.FYGPAGPYGIFAGR[166.11].D sp|O15173|PGRC2_HUMAN 1 1481.7331 1.48 6648 20042 2 1481.734414 741.8738 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3735.2 - 335224 - - - 0.8834 - 2.356 0.662 - 645.9 1 2 0 0.0013 14 0 0 0 5.04E+07 3.41E+07 - - - 6.0806 1 230117_WJC_METTL3_WT_vs_EV_F01.20047.20047.2 0.000355 18-Nov R.QEVVDLLLAR[166.11].G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1164.6742 1.23 6650 20047 2 1164.675261 583.3444 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3735.9 - 1.30E+06 - - - 0.917 - 2.289 0.446 - 589.7 1 2 0 0.0011 10 0 0 0 5.77E+07 4.68E+07 - - - 4.6463 1 230117_WJC_METTL3_WT_vs_EV_F01.20048.20048.2 3.84E-06 13/20 K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 8.86 6651 20048 2 1184.71457 593.3637 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3736.1 - 1.08E+06 - - - 1.4324 - 2.702 0.531 - 654 1 2 0 0.0017 11 0 0 0 1.88E+09 2.13E+08 - - - 5.6514 1 230117_WJC_METTL3_WT_vs_EV_F01.20049.20049.2 1.28E-06 14/24 R.VETPVLPPVLVPR.H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1414.8548 2.18 6652 20049 2 1414.853268 708.4347 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3736.2 - 1.65E+06 - - - -1.0736 - 2.376 0.56 - 461.7 1 2 0 -0.0015 13 0 0 0 1.95E+07 8.94E+06 - - - 5.3978 0.981 230117_WJC_METTL3_WT_vs_EV_F01.20050.20050.2 0.156 14-Jul R.DWVLNEFK.H "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1049.5182 1.6 6653 20050 2 1049.517187 525.7664 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3736.3 - 1.58E+06 - - - -0.9614 - 1.258 0.131 - 193 1 2 0 -0.001 8 0 0 0 1.19E+08 7.43E+07 - - - 0.7005 1 230117_WJC_METTL3_WT_vs_EV_F01.20051.20051.2 4.02E-07 13/22 K.YLGPAVLMQAYR.W sp|P21912|SDHB_HUMAN 1 1380.7224 3.13 6654 20051 2 1380.723123 691.3685 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 8.59 3736.4 - 1.55E+06 - - - 0.5294 - 2.235 0.467 - 531.9 1 2 0 0.0007 12 0 0 0 2.75E+07 8.79E+06 - - - 4.6061 1 230117_WJC_METTL3_WT_vs_EV_F01.20054.20054.2 1.66E-10 15/26 K.FYGPAGPYGIFAGR.D sp|O15173|PGRC2_HUMAN 1 1471.7248 1.48 6657 20054 2 1471.722984 736.8697 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3736.7 - 1.11E+06 - - - -1.2577 - 2.582 0.579 - 863.3 1 2 0 -0.0019 14 0 0 0 5.04E+07 3.41E+07 - - - 5.6973 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20055.20055.2 0.252 20-Oct -.MLLFVEQVASK.G "sp|Q71RC2|LARP4_HUMAN,tr|F8W1Z5|F8W1Z5_HUMAN" 2 1263.6897 0.31 6658 20055 2 1263.691629 632.8521 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 5.75 3736.8 - 1.08E+06 - - - 1.5304 - 2.131 0.345 - 302.9 1 2 0 0.0019 11 0 0 0 2.05E+07 6.52E+07 - - - 3.6353 0.9955 230117_WJC_METTL3_WT_vs_EV_F01.20057.20057.2 0.0294 22-Sep K.YLGPAVLMQAYR[166.11].W sp|P21912|SDHB_HUMAN 1 1390.7307 3.33 6660 20057 2 1390.730788 696.3726 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 8.59 3737.1 - 592536 - - - 0.0906 - 1.319 0.209 - 175.2 1 2 0 0.0001 12 0 0 0 1.98E+07 5.94E+06 - - - 1.3131 1 230117_WJC_METTL3_WT_vs_EV_F01.20062.20062.2 0.000827 18-Dec R.QEVVDLLLAR.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1154.6659 1.23 6663 20062 2 1154.664327 578.3402 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3737.8 - 4.86E+06 - - - -1.3822 - 2.37 0.491 - 775.1 1 2 0 -0.0016 10 0 0 0 5.77E+07 4.68E+07 - - - 5.0756 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.20063.20063.2 0.000922 22-Nov R.AVLTFALDSVER[166.11].K "sp|Q9NQT4|EXOS5_HUMAN,tr|M0R050|M0R050_HUMAN" 2 1329.7168 0.81 6664 20063 2 1329.72253 665.8657 Exosome complex component RRP46 OS=Homo sapiens OX=9606 GN=EXOSC5 PE=1 SV=1 4.37 3737.8 - 3.37E+06 - - - 4.3197 - 2.093 0.277 - 264.5 1 2 0 0.0057 12 0 0 0 1.26E+07 1.56E+07 - - - 3.0285 1 230117_WJC_METTL3_WT_vs_EV_F01.20065.20065.2 6.45E-07 20-Dec K.TAVETAVLLLR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1194.7211 8.83 6666 20065 2 1194.723158 598.3678 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3737.9 - 2.26E+06 - - - 1.6866 - 2.586 0.573 - 597.6 1 2 0 0.002 11 0 0 0 1.87E+09 2.12E+08 - - - 5.8428 1 230117_WJC_METTL3_WT_vs_EV_F01.20066.20066.2 4.15E-06 16-Sep K.YDWDLLAAR[166.11].S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1131.5588 1.67 6667 20066 2 1131.559446 566.7867 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3738 - 1.07E+06 - - - 0.5453 - 1.973 0.488 - 349.6 1 2 0 0.0006 9 0 0 0 9.95E+07 5.96E+07 - - - 4.6112 0.9896 230117_WJC_METTL3_WT_vs_EV_F01.20067.20067.2 8.39 14-Jul R.LIFLDSIK[136.11].S "sp|Q99996|AKAP9_HUMAN,tr|A0A0A0MRF6|A0A0A0MRF6_HUMAN,tr|A0A7P0TBH8|A0A7P0TBH8_HUMAN,tr|A0A7P0TAX3|A0A7P0TAX3_HUMAN,tr|A0A7P0T9A9|A0A7P0T9A9_HUMAN,tr|A0A7P0T8N5|A0A7P0T8N5_HUMAN,tr|A0A7P0TBI4|A0A7P0TBI4_HUMAN,tr|A0A7P0Z4Q5|A0A7P0Z4Q5_HUMAN,tr|A0A7P0Z4N5|A0A7P0Z4N5_HUMAN,tr|A0A7P0TAD6|A0A7P0TAD6_HUMAN,tr|A0A7P0T939|A0A7P0T939_HUMAN,tr|A0A7P0T928|A0A7P0T928_HUMAN,tr|A0A7P0TAA2|A0A7P0TAA2_HUMAN" 13 955.5834 1.39 6668 20067 2 955.584799 478.799 A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4 5.84 3738 - 747766 - - - 1.4965 - 1.219 0.11 - 113 1 2 0 0.0014 8 0 0 0 5.60E+06 4.04E+06 - - - 0.4503 1 230117_WJC_METTL3_WT_vs_EV_F01.20069.20069.2 9.63E-07 20-Dec K.TYSYLTPDLWK.E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1385.6867 0.31 6670 20069 2 1385.687419 693.8506 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.5 3738.2 - 536166 - - - 0.5059 - 2.334 0.513 - 381.4 1 2 0 0.0007 11 0 0 0 5.04E+06 1.65E+07 - - - 5.1227 0.9755 230117_WJC_METTL3_WT_vs_EV_F01.20073.20073.2 1.25 12-Jul K.DIILPFR.V "sp|Q96CW1|AP2M1_HUMAN,tr|A0A087WY71|A0A087WY71_HUMAN,tr|C9JJ47|C9JJ47_HUMAN,tr|E9PFW3|E9PFW3_HUMAN" 4 872.512 1.66 6672 20073 2 872.511208 437.2633 AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2 5.84 3738.7 - 633520 - - - -0.8951 - 1.579 0 - 235.5 1 2 0 -0.0008 7 0 0 0 2.55E+07 1.54E+07 - - - 0.4881 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20074.20074.2 0.00287 14-Aug R.IWYLLDGK[136.11].M "sp|Q9BYD1|RM13_HUMAN,tr|E5RFI2|E5RFI2_HUMAN" 2 1014.563 1.13 6673 20074 2 1014.563476 508.2888 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 5.83 3738.9 - 497915 - - - 0.5007 - 1.793 0.348 - 182.2 1 2 0 0.0005 8 0 0 0 2.02E+07 1.79E+07 - - - 3.3722 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.20081.20081.3 0.000116 15/40 K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 8.29 6678 20081 3 1184.713325 395.9116 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3739.6 - 984879 - - - 0.3815 - 2.749 0.39 - 295 1 2 0 0.0005 11 0 0 0 6.33E+07 7.64E+06 - - - 5.7607 0.981 230117_WJC_METTL3_WT_vs_EV_F01.20082.20082.2 1.26 16-Aug K.DGLLGAELR.L sp|P43026|GDF5_HUMAN 1 942.5134 3.85 6679 20082 2 942.515233 472.264 Growth\differentiation factor 5 OS=Homo sapiens OX=9606 GN=GDF5 PE=1 SV=3 4.37 3739.8 - 433213 - - - 1.8971 - 1.529 0.004 - 102.2 3 2 0 0.0018 9 0 0 0 8.95E+06 2.32E+06 - - - 0.0853 1 230117_WJC_METTL3_WT_vs_EV_F01.20084.20084.2 1.46E-05 18-Nov R.DAVLLVFANK.Q "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 5 1088.623 1.97 6681 20084 2 1088.624272 545.3188 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 5.84 3740 - 1.37E+06 - - - 1.1721 - 2.378 0.446 - 440.2 1 2 0 0.0013 10 0 0 0 1.97E+08 1.00E+08 - - - 4.7527 1 230117_WJC_METTL3_WT_vs_EV_F01.20086.20086.2 0.00331 18-Nov R.DAVLLVFANK[136.11].Q "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 5 1096.6372 1.97 6683 20086 2 1096.638535 549.3259 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 5.84 3740.3 - 729703 - - - 1.221 - 2.471 0.43 - 554.2 1 2 0 0.0013 10 0 0 0 1.95E+08 9.89E+07 - - - 4.7416 0.9455 230117_WJC_METTL3_WT_vs_EV_F01.20089.20089.2 0.00478 22-Dec K.PYR[166.11]PWGTEIGAF.- "sp|Q9Y5J3|HEY1_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 4 1402.6909 3.44 6686 20089 2 1402.690818 702.3527 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 6.43 3740.7 - 487244 - - - -0.0627 - 1.962 0.336 - 447.5 1 1 0 -0.0001 12 0 0 0 1.30E+07 3.77E+06 - - - 3.296 1 230117_WJC_METTL3_WT_vs_EV_F01.20090.20090.2 1.62E-05 13/20 K.FDGILGMAYPR.L "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1238.6118 10.9 6687 20090 2 1238.611771 620.3132 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.84 3740.8 - 414448 - - - -0.0065 - 2.414 0.454 - 613.8 1 2 0 0 11 0 0 0 2.65E+07 2.43E+06 - - - 4.7783 0.9956 230117_WJC_METTL3_WT_vs_EV_F01.20096.20096.3 0.0603 Oct-36 K.LFDIRPIWSR.N "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U4|Q5T7U4_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1301.7244 1.58 6693 20096 3 1301.725821 434.9154 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 9.6 3741.6 - 262609 - - - 1.0601 - 1.611 0.192 - 104.5 1 2 0 0.0014 10 0 0 0 2.21E+06 1.40E+06 - - - 2.0729 1 230117_WJC_METTL3_WT_vs_EV_F01.20104.20104.2 2.67E-06 16-Oct K.YDWDLLAAR.S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1121.5506 1.66 6700 20104 2 1121.550933 561.7826 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3742.5 - 1.15E+07 - - - 0.3335 - 1.995 0.558 - 419.2 1 2 0 0.0004 9 0 0 0 1.00E+08 6.03E+07 - - - 5.1603 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20109.20109.2 1.17E-05 13/28 R.LPLPSPALEYTLGSR.L sp|Q8IU81|I2BP1_HUMAN 1 1612.8825 2.77 6705 20109 2 1612.884117 807.4485 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3742.8 - 1.17E+06 - - - 1.0286 - 2.432 0.389 - 401 1 2 0 0.0017 15 0 0 0 6.70E+07 2.42E+07 - - - 4.0986 0.9949 230117_WJC_METTL3_WT_vs_EV_F01.20110.20110.2 0.00444 14-Jul K.WGVSDFIK.A "sp|Q92540|SMG7_HUMAN,tr|E9PD50|E9PD50_HUMAN,tr|B1ALB4|B1ALB4_HUMAN" 3 950.4862 1.93 6706 20110 2 950.483979 476.2504 Protein SMG7 OS=Homo sapiens OX=9606 GN=SMG7 PE=1 SV=2 5.84 3742.9 - 793987 - - - -2.303 - 1.204 0.406 - 103.3 1 2 0 -0.0022 8 0 0 0 4.71E+06 2.44E+06 - - - 2.5989 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.20116.20116.3 0.00247 15/40 K.TAVETAVLLLR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1194.7211 8.46 6710 20116 3 1194.719855 399.2477 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3743.6 - 563480 - - - -1.0781 - 2.403 0.447 - 305.1 1 2 0 -0.0013 11 0 0 0 6.32E+07 7.47E+06 - - - 6.0139 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20121.20121.2 0.000853 18-Sep R.LLVVYPWTQR.F "sp|P69892|HBG2_HUMAN,sp|P69891|HBG1_HUMAN,sp|P02042|HBD_HUMAN,sp|P02100|HBE_HUMAN,sp|P68871|HBB_HUMAN,tr|A0A2R8Y7R2|A0A2R8Y7R2_HUMAN,tr|E9PEW8|E9PEW8_HUMAN,tr|E9PFT6|E9PFT6_HUMAN,tr|F8W6P5|F8W6P5_HUMAN,tr|A0A2R8Y7X9|A0A2R8Y7X9_HUMAN" 10 1273.7183 999 6714 20121 2 1273.718834 637.8664 Hemoglobin subunit gamma-2 OS=Homo sapiens OX=9606 GN=HBG2 PE=1 SV=2 8.75 3744.2 - 5.89E+06 - - - 0.4247 - 1.815 0.378 - 365.5 1 2 0 0.0005 10 0 0 0 7.81E+07 0.00E+00 - - - 3.4966 1 230117_WJC_METTL3_WT_vs_EV_F01.20124.20124.2 1.81E-05 20/30 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 8.46 6716 20124 2 1549.885126 775.9487 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3744.6 - 2.72E+06 - - - 1.5059 - 3.293 0.521 - 1332 1 2 0 0.0023 16 0 0 0 7.60E+08 8.99E+07 - - - 5.8185 1 230117_WJC_METTL3_WT_vs_EV_F01.20126.20126.2 0.00678 13/20 R.TLVLLDNLNVR[166.11].E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1278.7535 1.37 6718 20126 2 1278.752807 640.384 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3744.8 - 3.08E+06 - - - -0.5466 - 2.676 0.416 - 683.2 1 2 0 -0.0007 11 0 0 0 6.31E+07 4.60E+07 - - - 4.7762 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20127.20127.2 0.00317 16-Nov K.SLTYLSILR.N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 3 1064.623 1.22 6719 20127 2 1064.62393 533.3188 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 8.46 3744.9 - 2.74E+06 - - - 0.8773 - 1.825 0.418 - 469.5 1 2 0 0.0009 9 0 0 0 1.57E+07 1.28E+07 - - - 3.8685 1 230117_WJC_METTL3_WT_vs_EV_F01.20128.20128.2 5.77E-09 15/22 K.LYDNLLEQNLIR.V sp|O00231|PSD11_HUMAN 1 1502.8093 1.79 6720 20128 2 1502.806259 752.4119 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3745 - 2.39E+06 - - - -2.0189 - 3.114 0.561 - 940.5 1 2 0 -0.003 12 0 0 0 4.05E+07 2.26E+07 - - - 6.1724 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.20129.20129.2 0.187 14-Sep R.SLLSILQR.S "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 928.5706 2.25 6721 20129 2 928.569873 465.2926 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 9.47 3745.2 - 1.85E+06 - - - -0.7463 - 1.882 0.197 - 332 1 2 0 -0.0007 8 0 0 0 1.30E+07 5.76E+06 - - - 2.4029 1 230117_WJC_METTL3_WT_vs_EV_F01.20130.20130.2 0.000271 16/28 R.LPLPSPALEYTLGSR[166.11].L sp|Q8IU81|I2BP1_HUMAN 1 1622.8907 2.77 6722 20130 2 1622.882421 812.4526 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3745.3 - 2.27E+06 - - - -5.1186 - 2.679 0.481 - 630.6 1 2 0 -0.0083 15 0 0 0 6.70E+07 2.42E+07 - - - 5.0138 1 230117_WJC_METTL3_WT_vs_EV_F01.20131.20131.2 1.90E-05 25/30 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 999 6723 20131 2 1786.999508 894.5093 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3745.4 - 1.61E+06 - - - -2.5305 - 4.807 0.629 - 2181.9 1 2 0 -0.0045 16 0 0 0 3.89E+07 0.00E+00 - - - 7.5455 1 230117_WJC_METTL3_WT_vs_EV_F01.20132.20132.2 2.53E-08 15/22 K.LYDNLLEQNLIR[166.11].V sp|O00231|PSD11_HUMAN 1 1512.8176 1.79 6724 20132 2 1512.817746 757.4161 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3745.6 - 1.54E+06 - - - 0.121 - 3.1 0.583 - 891 1 2 0 0.0002 12 0 0 0 4.05E+07 2.26E+07 - - - 6.3239 0.9944 230117_WJC_METTL3_WT_vs_EV_F01.20136.20136.2 0.702 12-Jul R.VTLLLFK.D "sp|Q9Y3C4|TPRKB_HUMAN,sp|Q86YN1|DOPP1_HUMAN,tr|H7C1Z8|H7C1Z8_HUMAN,tr|H7BXT6|H7BXT6_HUMAN" 4 832.5422 1.51 6728 20136 2 832.54207 417.2784 EKC\KEOPS complex subunit TPRKB OS=Homo sapiens OX=9606 GN=TPRKB PE=1 SV=1 8.72 3746.1 - 955751 - - - -0.1874 - 1.482 0.132 - 174.5 1 2 0 -0.0002 7 0 0 0 2.75E+06 1.82E+06 - - - 1.2624 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.20137.20137.2 0.00102 18-Sep R.LWGDIYFNPK[136.11].T sp|Q15029|U5S1_HUMAN 1 1259.643 1.78 6729 20137 2 1259.641994 630.8288 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.83 3746.2 - 935582 - - - -0.8058 - 1.804 0.19 - 205.6 2 2 0 -0.001 10 0 0 0 1.18E+07 6.59E+06 - - - 1.9564 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20138.20138.2 0.00024 24-Nov R.ATVGILITTIASK[136.11].G "sp|Q92973|TNPO1_HUMAN,tr|A0A7P0T9C0|A0A7P0T9C0_HUMAN,tr|A0A7P0TBF0|A0A7P0TBF0_HUMAN,tr|A0A7P0T944|A0A7P0T944_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 5 1294.7952 1.82 6730 20138 2 1294.795844 648.4049 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 8.8 3746.3 - 715041 - - - 0.5337 - 1.845 0.446 - 268.8 1 2 0 0.0007 13 0 0 0 3.79E+06 2.08E+06 - - - 3.9069 1 230117_WJC_METTL3_WT_vs_EV_F01.20146.20146.3 1.07E-05 13/60 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 89.71 6736 20146 3 1787.005662 596.6753 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3747.4 - 4.86E+06 - - - 0.9133 - 2.868 0.582 - 286.4 1 2 0 0.0016 16 0 0 0 1.55E+08 1.73E+06 - - - 7.7317 1 230117_WJC_METTL3_WT_vs_EV_F01.20148.20148.2 4.28E-05 19/30 R.ALIAGGGAPEIELALR[166.11].L sp|P50991|TCPD_HUMAN 1 1559.8911 8.45 6738 20148 2 1559.891181 780.9528 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3747.5 - 5.69E+06 - - - 0.0763 - 2.986 0.433 - 1369.3 1 2 0 0.0001 16 0 0 0 7.59E+08 8.98E+07 - - - 4.9286 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.20149.20149.2 0.00709 12-Jul K.NMFAIWR.V "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 936.464 0.95 6739 20149 2 936.46428 469.2393 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3747.6 - 5.26E+06 - - - 0.3065 - 1.158 0.379 - 165.2 1 2 0 0.0003 7 0 0 0 3.30E+07 3.47E+07 - - - 2.305 1 230117_WJC_METTL3_WT_vs_EV_F01.20150.20150.2 2.11E-05 18-Nov K.GIGFLTSGWR[166.11].F sp|Q8IXM3|RM41_HUMAN 1 1102.5799 1.18 6740 20150 2 1102.581218 552.2972 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 9.75 3747.6 - 4.14E+06 - - - 1.1963 - 2.286 0.484 - 449.8 1 2 0 0.0013 10 0 0 0 3.44E+07 2.91E+07 - - - 4.9233 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.20151.20151.2 0.102 16-Nov R.NLLGLALGR.L sp|Q8N5L8|RP25L_HUMAN 1 925.5709 1.14 6741 20151 2 925.57121 463.7927 Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1 9.75 3747.6 - 3.02E+06 - - - 0.3338 - 1.786 0.148 - 430.7 1 2 0 0.0003 9 0 0 0 6.12E+07 5.35E+07 - - - 1.8119 1 230117_WJC_METTL3_WT_vs_EV_F01.20153.20153.2 7.86E-10 14/20 R.PMEVFMC[160.03]SVLK.R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1339.6338 1.14 6743 20153 2 1339.634093 670.8242 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3747.7 - 2.84E+06 - - - 0.1911 - 2.802 0.669 - 814.6 1 1 0 0.0003 11 0 0 0 2.63E+07 2.31E+07 - - - 6.7694 1 230117_WJC_METTL3_WT_vs_EV_F01.20155.20155.3 7.05E-09 19/60 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 8.37 6745 20155 3 1549.884646 517.6349 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3747.8 - 2.53E+06 - - - 1.1962 - 3.255 0.53 - 599.9 1 2 0 0.0019 16 0 0 0 4.44E+07 5.31E+06 - - - 7.4767 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20156.20156.2 0.00168 16-Sep R.MLFDYLADK.H "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V570|A0A7I2V570_HUMAN,tr|A0A7I2V2Q9|A0A7I2V2Q9_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V5K7|A0A7I2V5K7_HUMAN,tr|A0A7I2V3W9|A0A7I2V3W9_HUMAN,tr|H0YBR5|H0YBR5_HUMAN,tr|A0A7I2V429|A0A7I2V429_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN,tr|A0A161SXE1|A0A161SXE1_HUMAN" 20 1114.5369 0.41 6746 20156 2 1114.538281 558.2757 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 4.21 3747.9 - 3.57E+06 - - - 1.2543 - 1.512 0.451 - 168.5 1 2 0 0.0014 9 0 0 0 3.11E+07 7.54E+07 - - - 3.5677 1 230117_WJC_METTL3_WT_vs_EV_F01.20157.20157.2 1.28E-07 13/20 R.PMEVFMC[160.03]SVLK[136.11].R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1347.648 1.14 6747 20157 2 1347.650191 674.8313 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3747.9 - 2.06E+06 - - - 1.5983 - 2.664 0.6 - 601.1 1 1 0 0.0022 11 0 0 0 2.63E+07 2.31E+07 - - - 6.1226 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20160.20160.2 0.01 20-Sep R.VFSWGFGGYGR.L sp|Q9P258|RCC2_HUMAN 1 1231.5774 1.87 6750 20160 2 1231.579358 616.796 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 8.72 3748.3 - 968924 - - - 1.5549 - 1.94 0.373 - 272.9 1 2 0 0.0019 11 0 0 0 9.84E+06 5.27E+06 - - - 3.5881 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20161.20161.2 0.000937 16-Sep R.GFFGFPGPR.S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 980.4868 2.22 6751 20161 2 980.486926 491.2507 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3748.4 - 774034 - - - 0.0908 - 1.793 0.474 - 241.4 1 2 0 0.0001 9 0 0 0 3.05E+07 1.38E+07 - - - 4.2312 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20164.20164.2 0.000887 13/20 R.VFSWGFGGYGR[166.11].L sp|Q9P258|RCC2_HUMAN 1 1241.5857 1.87 6754 20164 2 1241.587745 621.8001 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 8.72 3748.6 - 456791 - - - 1.6366 - 2.136 0.456 - 165.5 1 2 0 0.002 11 0 0 0 9.84E+06 5.27E+06 - - - 4.4615 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.20165.20165.2 0.000849 13/26 K.IPPPVIMVQNVSFK.Y sp|Q9UG63|ABCF2_HUMAN 1 1567.8796 2.83 6755 20165 2 1567.880036 784.9471 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.75 3748.8 - 439368 - - - 0.2647 - 2.141 0.3 - 512.1 1 2 0 0.0004 14 0 0 0 6.52E+06 2.30E+06 - - - 3.167 1 230117_WJC_METTL3_WT_vs_EV_F01.20167.20167.3 3.25E-07 15/52 K.IPPPVIMVQNVSFK.Y sp|Q9UG63|ABCF2_HUMAN 1 1567.8796 3.47 6756 20167 3 1567.88106 523.6338 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.75 3749 - 1.56E+06 - - - 0.9178 - 3.004 0.52 - 497.6 1 2 0 0.0014 14 0 0 0 4.10E+06 1.18E+06 - - - 7.2602 0.9884 230117_WJC_METTL3_WT_vs_EV_F01.20169.20169.2 2.64 16-Aug R.NLLGLALGR[166.11].L sp|Q8N5L8|RP25L_HUMAN 1 935.5792 1.14 6758 20169 2 935.57888 468.7969 Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1 9.75 3749.2 - 2.37E+07 - - - -0.311 - 1.205 0.161 - 228.9 1 2 0 -0.0003 9 0 0 0 6.12E+07 5.35E+07 - - - 0.7696 0.8951 230117_WJC_METTL3_WT_vs_EV_F01.20170.20170.2 5.82 18-Jul K.ISLLTDSLLK.V "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN,tr|Q5T2X4|Q5T2X4_HUMAN" 3 1101.6645 -1 6759 20170 2 1101.664872 551.8395 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.84 3749.2 - 7.53E+06 - - - 0.3141 - 0.865 0.057 - 66.6 1 2 0 0.0003 10 0 0 0 0.00E+00 0.00E+00 - - - -0.9429 1 230117_WJC_METTL3_WT_vs_EV_F01.20172.20172.3 1.74E-10 23/76 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 3.26 6761 20172 3 2197.088129 733.3694 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3749.4 - 3.99E+06 - - - 0.8525 - 4.488 0.585 - 588.4 1 2 0 0.0019 20 0 0 0 9.19E+06 2.82E+06 - - - 8.7041 0.999 230117_WJC_METTL3_WT_vs_EV_F01.20174.20174.2 0.0319 16-Aug R.GSLITSLLR[166.11].S sp|Q53FA7|QORX_HUMAN 1 968.5894 0.91 6763 20174 2 968.589444 485.302 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3749.7 - 3.45E+06 - - - 0.0444 - 1.871 0.266 - 164.7 1 2 0 0 9 0 0 0 6.99E+06 7.68E+06 - - - 2.8181 0.9822 230117_WJC_METTL3_WT_vs_EV_F01.20175.20175.3 1.52 Dec-56 R.LPLPSPALEYTLGSR.L sp|Q8IU81|I2BP1_HUMAN 1 1612.8825 2.57 6764 20175 3 1612.883976 538.6348 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3749.7 - 2.91E+06 - - - 0.9412 - 1.813 0.094 - 201.5 1 2 0 0.0015 15 0 0 0 9.73E+06 3.78E+06 - - - 1.1401 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.20176.20176.2 0.105 16-Oct R.GSLITSLLR.S sp|Q53FA7|QORX_HUMAN 1 958.5811 0.91 6765 20176 2 958.580723 480.2978 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3749.8 - 2.73E+06 - - - -0.4256 - 1.897 0.217 - 272.3 1 2 0 -0.0004 9 0 0 0 6.99E+06 7.68E+06 - - - 2.496 1 230117_WJC_METTL3_WT_vs_EV_F01.20177.20177.2 5.76E-06 18-Oct R.VFYYLVQDLK.C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1286.6911 0.95 6766 20177 2 1286.695665 644.3528 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3749.9 - 2.09E+06 - - - 3.5673 - 2.204 0.457 - 345.4 1 2 0 0.0046 10 0 0 0 1.05E+08 1.11E+08 - - - 4.6209 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.20178.20178.2 0.0165 12-Aug R.WIVNLIR.N "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 15 912.5545 0.93 6767 20178 2 912.554749 457.2845 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 9.75 3750 - 1.70E+06 - - - 0.2488 - 1.48 0.223 - 392.8 1 2 0 0.0002 7 0 0 0 5.53E+07 5.93E+07 - - - 1.9302 1 230117_WJC_METTL3_WT_vs_EV_F01.20179.20179.2 7.94E-07 18-Nov R.VFYYLVQDLK[136.11].C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1294.7053 0.95 6768 20179 2 1294.710225 648.3599 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3750.1 - 1.53E+06 - - - 3.8233 - 2.384 0.549 - 488.2 1 2 0 0.005 10 0 0 0 1.05E+08 1.11E+08 - - - 5.5194 0.9893 230117_WJC_METTL3_WT_vs_EV_F01.20180.20180.3 1.72 Jul-40 R.TLVLLDNLNVR.E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1268.7452 -1 6769 20180 3 1268.743932 423.9224 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3750.2 - 1.40E+06 - - - -1.0278 - 1.43 0.228 - 42.7 1 2 0 -0.0013 11 0 0 0 0.00E+00 0.00E+00 - - - 2.0977 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20188.20188.2 0.000483 20-Aug K.TVLELQYVLDK[136.11].L "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1327.7479 1.15 6776 20188 2 1327.747919 664.8812 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.37 3751.1 - 3.66E+06 - - - 0.0377 - 1.79 0.47 - 147.7 1 2 0 0.0001 11 0 0 0 2.67E+08 2.33E+08 - - - 4.0874 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20190.20190.2 8.19E-05 18-Oct R.YVEFNLLYDR.G "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1330.6558 1.07 6778 20190 2 1330.656489 666.3352 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.37 3751.2 - 4.56E+06 - - - 0.5539 - 1.914 0.457 - 360.8 1 2 0 0.0007 10 0 0 0 2.57E+07 2.39E+07 - - - 4.2283 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20191.20191.2 0.000327 18-Sep K.YFSSMAEFLK.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1221.574 1.26 6779 20191 2 1221.575536 611.7943 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 3751.3 - 4.44E+06 - - - 1.2598 - 1.737 0.397 - 159.2 1 2 0 0.0015 10 0 0 0 4.17E+07 3.31E+07 - - - 3.514 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20194.20194.2 0.00191 14-Sep R.YGLEC[160.03]LFR.Y "sp|Q6PKG0|LARP1_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN" 3 1056.5063 0.73 6782 20194 2 1056.507163 529.2604 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 5.99 3751.6 - 2.74E+06 - - - 0.8623 - 1.865 0.347 - 310 1 2 0 0.0009 8 0 0 0 7.92E+06 1.09E+07 - - - 3.4834 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20195.20195.2 0.000301 16-Sep R.GFFGFPGPR[166.11].S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 990.4951 2.26 6783 20195 2 990.494925 496.2548 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3751.7 - 2.03E+06 - - - -0.1837 - 1.76 0.465 - 216.7 1 2 0 -0.0002 9 0 0 0 3.05E+07 1.35E+07 - - - 4.1109 1 230117_WJC_METTL3_WT_vs_EV_F01.20201.20201.2 1.53E-08 22-Dec K.C[160.03]PLDPYFIMPDK.C "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 3 1494.6887 -1 6789 20201 2 1494.690064 748.3516 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4.21 3752.4 - 907476 - - - 0.9065 - 2.535 0.604 - 319 1 2 0 0.0014 12 0 0 0 0.00E+00 0.00E+00 - - - 5.9492 0.9617 230117_WJC_METTL3_WT_vs_EV_F01.20205.20205.2 0.00851 22-Aug Y.VLNPLAPEFIPR.A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1364.7816 33.38 6793 20205 2 1364.783241 683.3981 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.97 3753 - 419719 - - - 1.1863 - 1.998 0.32 - 177.7 1 1 0 0.0016 12 0 0 0 2.83E+06 8.49E+04 - - - 3.2252 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.20211.20211.2 0.0557 12-Aug R.WIVNLIR[166.11].N "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 15 922.5628 0.93 6798 20211 2 922.562826 462.2887 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 9.75 3753.6 - 3.15E+07 - - - 0.0369 - 1.442 0.257 - 379.6 1 2 0 0 7 0 0 0 5.53E+07 5.93E+07 - - - 2.099 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.20213.20213.2 0.00516 18-Sep R.YVEFNLLYDR[166.11].G "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1340.664 1.07 6800 20213 2 1340.663676 671.3393 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.37 3753.7 - 9.85E+06 - - - -0.2581 - 1.846 0.368 - 234 1 2 0 -0.0003 10 0 0 0 2.57E+07 2.39E+07 - - - 3.4701 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.20214.20214.2 0.00547 22-Sep K.LGAIFLEGVTVK.G sp|O60942|MCE1_HUMAN 1 1245.7333 25.71 6801 20214 2 1245.738596 623.8739 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 6 3753.7 - 9.66E+06 - - - 4.2714 - 1.797 0.399 - 179.8 1 2 0 0.0053 12 0 0 0 2.48E+07 9.64E+05 - - - 3.5285 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.20216.20216.2 0.00058 14-Sep R.WLLSDYVK.V "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN,tr|C9JZH6|C9JZH6_HUMAN" 3 1022.5437 -1 6803 20216 2 1022.544713 512.2791 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.83 3753.9 - 5.42E+06 - - - 1.0073 - 1.728 0.281 - 367.3 1 2 0 0.001 8 0 0 0 0.00E+00 0.00E+00 - - - 2.7658 0.9554 230117_WJC_METTL3_WT_vs_EV_F01.20217.20217.2 3.46 16-Jun M.KPSWLQC[160.03]RK[136.11].V "sp|Q9H6R3|ACSS3_HUMAN,tr|A0A0B4J1R2|A0A0B4J1R2_HUMAN" 2 1209.6532 - 6804 20217 2 1209.653134 605.8339 "Acyl-CoA synthetase short-chain family member 3, mitochondrial OS=Homo sapiens OX=9606 GN=ACSS3 PE=1 SV=1" 10.06 3753.9 - 5.13E+06 - - - -0.0521 - 1.216 0.018 - 106.3 1 2 0 -0.0001 9 0 0 0 - - - - - -0.2603 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.20219.20219.2 0.107 14-Oct R.LLLEDLVK.K "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 941.5797 1.52 6806 20219 2 941.579649 471.7971 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 4.37 3754.1 - 4.25E+06 - - - -0.0903 - 1.669 0.2 - 235.2 1 2 0 -0.0001 8 0 0 0 7.05E+06 4.65E+06 - - - 2.063 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.20221.20221.2 0.0341 14-Sep K.TMLTELLR[166.11].G "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 985.5506 1.34 6808 20221 2 985.550732 493.7826 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 5.66 3754.3 - 3.08E+06 - - - 0.1613 - 1.825 0.352 - 356 1 2 0 0.0002 8 0 0 0 6.89E+06 5.14E+06 - - - 3.4552 0.9933 230117_WJC_METTL3_WT_vs_EV_F01.20222.20222.2 0.000223 20-Sep R.YLLLLAAGDPR.E "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1200.6867 3.9 6809 20222 2 1200.682389 601.3506 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.84 3754.4 - 2.50E+06 - - - -3.5563 - 1.888 0.335 - 177.4 1 2 0 -0.0043 11 0 0 0 9.09E+06 2.33E+06 - - - 3.2332 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.20223.20223.2 0.0222 12-Jul K.LFFLQVK[136.11].E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 901.5517 0.82 6810 20223 2 901.552463 451.7831 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3754.5 - 1.92E+06 - - - 0.874 - 1.286 0.174 - 139.9 1 2 0 0.0008 7 0 0 0 9.72E+06 1.19E+07 - - - 1.1229 0.9922 230117_WJC_METTL3_WT_vs_EV_F01.20224.20224.2 0.0736 16-Sep K.INMLVIELK[136.11].S "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1079.6504 1 6811 20224 2 1079.655087 540.8325 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3754.7 - 1.91E+06 - - - 4.3384 - 1.517 0.214 - 161.8 1 2 0 0.0047 9 0 0 0 3.21E+06 3.22E+06 - - - 1.8258 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.20225.20225.2 9.84E-05 24-Nov R.FADALGLELAQVK.V sp|O95685|PPR3D_HUMAN 1 1373.7555 4.9 6812 20225 2 1373.754396 687.885 Protein phosphatase 1 regulatory subunit 3D OS=Homo sapiens OX=9606 GN=PPP1R3D PE=1 SV=1 4.37 3754.8 - 1.82E+06 - - - -0.7796 - 2.337 0.423 - 279.7 1 2 0 -0.0011 13 0 0 0 3.54E+06 7.22E+05 - - - 4.3436 0.9956 230117_WJC_METTL3_WT_vs_EV_F01.20227.20227.2 0.185 16-Aug R.LELPADLLR[166.11].Q "sp|Q96NU1|SAM11_HUMAN,tr|A0A087WYW1|A0A087WYW1_HUMAN,tr|A0A087WX24|A0A087WX24_HUMAN,tr|A0A087X1J5|A0A087X1J5_HUMAN,tr|A0A087X223|A0A087X223_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|A0A087WXB3|A0A087WXB3_HUMAN,tr|H7C3J6|H7C3J6_HUMAN,tr|A0A087WYU3|A0A087WYU3_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 10 1048.6156 3.35 6814 20227 2 1048.614733 525.3151 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3 4.37 3755.1 - 1.64E+06 - - - -0.8421 - 1.546 0.204 - 128.1 1 2 0 -0.0009 9 0 0 0 1.68E+07 5.02E+06 - - - 1.8079 0.8905 230117_WJC_METTL3_WT_vs_EV_F01.20228.20228.2 2.24 28-May R.DLLNHAFFAEDTGLR[166.11].V "sp|Q9BYP7|WNK3_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN" 2 1727.8507 0.001 6815 20228 2 1727.848949 864.9326 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 4.54 3755.2 - 1.45E+06 - - - -0.9868 - 1.034 0.101 - 28.4 7 2 0 -0.0017 15 0 0 0 0.00E+00 5.36E+06 - - - -0.5089 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20233.20233.2 0.00093 18-Oct R.QEVVELLLAR.G "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1168.6816 1.34 6819 20233 2 1168.683323 585.3481 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.53 3755.7 - 2.90E+06 - - - 1.4974 - 2.258 0.391 - 421.9 1 2 0 0.0018 10 0 0 0 1.49E+07 1.12E+07 - - - 4.2018 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20234.20234.2 2.49E-05 16-Aug R.LTSFITVFK.Y "sp|Q13617|CUL2_HUMAN,tr|Q5T2B5|Q5T2B5_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 3 1054.6063 1.94 6820 20234 2 1054.608111 528.3104 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 8.75 3755.8 - 2.32E+06 - - - 1.7333 - 2.042 0.335 - 187.7 1 2 0 0.0018 9 0 0 0 1.26E+07 6.48E+06 - - - 3.5802 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20237.20237.2 3.41E-06 16-Oct R.NSYLEVLLK.L sp|Q15084|PDIA6_HUMAN 1 1077.607 0.5 6823 20237 2 1077.608035 539.8108 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 6 3756 - 1.69E+06 - - - 0.9503 - 2.055 0.462 - 349.5 1 2 0 0.001 9 0 0 0 1.18E+07 2.35E+07 - - - 4.5368 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.20242.20242.2 0.0357 14-Sep R.WLLSDYVK[136.11].V "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN,tr|C9JZH6|C9JZH6_HUMAN" 3 1030.5579 -1 6828 20242 2 1030.560521 516.2862 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.83 3756.5 - 932688 - - - 2.5598 - 1.692 0.267 - 244.4 1 2 0 0.0026 8 0 0 0 0.00E+00 0.00E+00 - - - 2.5984 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.20243.20243.2 0.0145 14-Aug K.AIFLFVDK[136.11].T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 959.5572 1.17 6829 20243 2 959.558616 480.7859 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3756.6 - 589284 - - - 1.5236 - 1.522 0.363 - 226.2 1 2 0 0.0015 8 0 0 0 1.05E+07 9.00E+06 - - - 2.9884 1 230117_WJC_METTL3_WT_vs_EV_F01.20252.20252.2 2.08E-05 20-Oct K.LLVYEALEYAK.R "sp|Q96DB5|RMD1_HUMAN,tr|H0YB83|H0YB83_HUMAN,tr|E5RH53|E5RH53_HUMAN,tr|H0YB03|H0YB03_HUMAN" 4 1310.7122 -1 6837 20252 2 1310.714763 656.3634 Regulator of microtubule dynamics protein 1 OS=Homo sapiens OX=9606 GN=RMDN1 PE=1 SV=1 4.53 3757.8 - 253938 - - - 1.9516 - 2.059 0.509 - 341.9 1 2 0 0.0026 11 0 0 0 0.00E+00 0.00E+00 - - - 4.7534 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.20254.20254.2 0.00955 18-Oct R.DLASVQALLR[166.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1094.6323 0.86 6839 20254 2 1094.637689 548.3234 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3757.9 - 5.96E+06 - - - 4.8975 - 2.08 0.333 - 328.8 1 2 0 0.0054 10 0 0 0 2.49E+07 2.90E+07 - - - 3.5431 0.9902 230117_WJC_METTL3_WT_vs_EV_F01.20255.20255.2 0.727 16-Jul K.LEATINELV.- sp|P10599|THIO_HUMAN 1 1000.5441 - 6840 20255 2 1000.548852 501.2793 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 3.79 3758 - 2.39E+06 - - - 4.7724 - 1.593 0.204 - 94.4 1 2 0 0.0048 9 0 0 0 - - - - - 1.8933 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.20256.20256.2 0.00672 14-Aug K.AIFLFVDK.T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 951.543 1.17 6841 20256 2 951.545982 476.7788 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3758.1 - 1.57E+06 - - - 3.1822 - 1.548 0.293 - 227.2 1 2 0 0.003 8 0 0 0 1.05E+07 9.00E+06 - - - 2.522 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.20258.20258.2 0.0068 16-Aug K.ELTLGNLLR.M "sp|Q9H4H8|FA83D_HUMAN,tr|A0A087WXK8|A0A087WXK8_HUMAN" 2 1027.6026 0.57 6843 20258 2 1027.607591 514.8086 Protein FAM83D OS=Homo sapiens OX=9606 GN=FAM83D PE=1 SV=3 6.1 3758.4 - 751096 - - - 4.8618 - 1.746 0.336 - 139.3 1 2 0 0.005 9 0 0 0 6.21E+06 1.10E+07 - - - 3.1335 1 230117_WJC_METTL3_WT_vs_EV_F01.20261.20261.2 1.19E-08 28-Dec L.LVSVSALTLATETVR.S sp|P50991|TCPD_HUMAN 1 1558.893 11.68 6846 20261 2 1558.896413 780.4538 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6 3758.8 - 505565 - - - 2.1746 - 2.726 0.608 - 515.9 1 1 0 0.0034 15 0 0 0 1.00E+07 8.60E+05 - - - 5.9961 0.9937 230117_WJC_METTL3_WT_vs_EV_F01.20262.20262.2 0.103 18-Jul K.EGLSFLGGLR.S "sp|Q6WKZ4|RFIP1_HUMAN,tr|E7EX40|E7EX40_HUMAN" 2 1047.5713 1.11 6847 20262 2 1047.57483 524.7929 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 6.1 3758.9 - 493028 - - - 3.3745 - 1.424 0.194 - 106.4 1 2 0 0.0035 10 0 0 0 2.24E+06 2.02E+06 - - - 1.4594 1 230117_WJC_METTL3_WT_vs_EV_F01.20264.20264.2 1.75E-06 22-Nov K.FLQDTIEEMALK[136.11].N sp|O95202|LETM1_HUMAN 1 1444.7363 4.75 6849 20264 2 1444.738505 723.3754 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.14 3759.2 - 458097 - - - 1.5138 - 2.34 0.511 - 351.7 1 2 0 0.0022 12 0 0 0 3.59E+07 7.57E+06 - - - 5.0515 0.9825 230117_WJC_METTL3_WT_vs_EV_F01.20266.20266.2 2.2 12-Jun K.ELLEFLR[166.11].L sp|Q96L94|SNX22_HUMAN 1 928.5257 1.17 6851 20266 2 928.528529 465.2701 Sorting nexin-22 OS=Homo sapiens OX=9606 GN=SNX22 PE=1 SV=1 4.53 3759.4 - 421562 - - - 3.0058 - 1.392 0.056 - 104 1 2 0 0.0028 7 0 0 0 1.52E+06 1.29E+06 - - - 0.5017 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.20268.20268.2 0.00178 24-Aug R.FSPLMTAAVLGTR.G "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 1362.733 -1 6853 20268 2 1362.730975 682.3738 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 9.75 3759.7 - 354560 - - - -1.4544 - 1.735 0.392 - 165.5 1 2 0 -0.002 13 0 0 0 0.00E+00 0.00E+00 - - - 3.3499 0.9389 230117_WJC_METTL3_WT_vs_EV_F01.20272.20272.2 5.86 12-Jul K.LIEFLLK.A "sp|Q5H9R7|PP6R3_HUMAN,tr|H7BXH2|H7BXH2_HUMAN,tr|E9PNN8|E9PNN8_HUMAN,tr|E9PKF6|E9PKF6_HUMAN,tr|E9PKG4|E9PKG4_HUMAN" 5 874.5528 1.97 6856 20272 2 874.558685 438.2837 Serine\threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PPP6R3 PE=1 SV=2 6 3760.2 - 312221 - - - 6.7394 - 1.532 0.137 - 122.8 1 2 0 0.0059 7 0 0 0 4.98E+06 2.52E+06 - - - 1.4027 0.9912 230117_WJC_METTL3_WT_vs_EV_F01.20273.20273.2 0.0358 22-Aug K.LLPELLQPYTER.V sp|Q13057|COASY_HUMAN 1 1470.8082 5.1 6857 20273 2 1470.816475 736.4114 Bifunctional coenzyme A synthase OS=Homo sapiens OX=9606 GN=COASY PE=1 SV=4 4.53 3760.3 - 141952 - - - 5.6058 - 1.719 0.286 - 191.6 1 2 0 0.0082 12 0 0 0 1.38E+06 2.70E+05 - - - 2.5762 0.982 230117_WJC_METTL3_WT_vs_EV_F01.20289.20289.2 1.45 14-Jul K.ALIIIWAK[136.11].V "sp|P57678|GEMI4_HUMAN,tr|I3L4M4|I3L4M4_HUMAN,tr|E7EN12|E7EN12_HUMAN,tr|I3L4A4|I3L4A4_HUMAN,tr|I3L2C7|I3L2C7_HUMAN,tr|I3L399|I3L399_HUMAN" 6 934.6095 0.96 6873 20289 2 934.612216 468.312 Gem-associated protein 4 OS=Homo sapiens OX=9606 GN=GEMIN4 PE=1 SV=2 8.8 3762.3 - 143273 - - - 2.8803 - 1.452 0.036 - 119.9 1 2 0 0.0027 8 0 0 0 9.02E+05 9.35E+05 - - - 0.4308 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20290.20290.2 0.0998 26-Dec K.ALLAVIGADSVTLK[136.11].N sp|Q9NYH9|UTP6_HUMAN 1 1377.8323 1.53 6874 20290 2 1377.835622 689.9234 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3762.4 - 134943 - - - 2.435 - 2.515 0.333 - 413 1 2 0 0.0034 14 0 0 0 8.75E+06 5.70E+06 - - - 3.8139 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20295.20295.2 0.00111 20-Dec R.AFITNIPFDVK[136.11].W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1271.7005 2.34 6878 20295 2 1271.70273 636.8575 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3763 - 1.94E+06 - - - 1.7347 - 1.975 0.453 - 499.4 1 2 0 0.0022 11 0 0 0 7.07E+07 3.02E+07 - - - 4.2273 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.20296.20296.2 0.0442 14-Jul K.EILIPVFK.N sp|P53396|ACLY_HUMAN 1 957.5899 1.37 6879 20296 2 957.591315 479.8022 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3763 - 1.93E+06 - - - 1.4724 - 1.406 0.229 - 160.8 1 2 0 0.0014 8 0 0 0 4.62E+07 3.37E+07 - - - 1.7596 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.20297.20297.2 0.0125 14-Jul K.EILIPVFK[136.11].N sp|P53396|ACLY_HUMAN 1 965.6041 1.37 6880 20297 2 965.605533 483.8093 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3763.1 - 1.66E+06 - - - 1.4789 - 1.46 0.372 - 162.8 1 2 0 0.0014 8 0 0 0 4.63E+07 3.37E+07 - - - 2.9295 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.20298.20298.2 0.195 26-Oct K.LLTGELLPTDGMIR.K sp|Q9UG63|ABCF2_HUMAN 1 1527.8331 2.15 6881 20298 2 1527.831643 764.9238 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.37 3763.2 - 1.48E+06 - - - -0.9307 - 2.276 0.327 - 203.4 1 2 0 -0.0014 14 0 0 0 2.00E+07 9.30E+06 - - - 3.5196 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20300.20300.2 0.00392 14/26 K.ALLAVIGADSVTLK.N sp|Q9NYH9|UTP6_HUMAN 1 1369.8181 1.48 6883 20300 2 1369.8198 685.9163 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3763.4 - 936231 - - - 1.2651 - 2.795 0.396 - 777.2 1 2 0 0.0017 14 0 0 0 7.70E+06 5.21E+06 - - - 4.5446 1 230117_WJC_METTL3_WT_vs_EV_F01.20302.20302.2 0.00469 15/26 K.LLTGELLPTDGMIR[166.11].K sp|Q9UG63|ABCF2_HUMAN 1 1537.8413 2.15 6885 20302 2 1537.844121 769.9279 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.37 3763.6 - 738602 - - - 1.8116 - 2.498 0.447 - 588.2 1 2 0 0.0028 14 0 0 0 2.00E+07 9.30E+06 - - - 4.639 0.962 230117_WJC_METTL3_WT_vs_EV_F01.20304.20304.2 1.44 16-Jun R.EPLFLDLPK.S "sp|O60911|CATL2_HUMAN,tr|A0A7P0T983|A0A7P0T983_HUMAN,tr|A0A7P0Z415|A0A7P0Z415_HUMAN" 3 1070.6012 1.83 6887 20304 2 1070.605115 536.3079 Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 SV=2 4.37 3763.7 - 686457 - - - 3.6587 - 1.136 0.131 - 63.7 2 2 0 0.0039 9 0 0 0 1.84E+06 1.01E+06 - - - 0.2418 1 230117_WJC_METTL3_WT_vs_EV_F01.20306.20306.2 8.45E-06 24-Nov R.ALDPAAAAYLFQR.Q "sp|O75376|NCOR1_HUMAN,tr|E7EVK1|E7EVK1_HUMAN" 2 1405.7354 1.88 6889 20306 2 1405.742333 703.875 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 5.88 3764 - 330897 - - - 4.9319 - 2.649 0.414 - 511.7 1 2 0 0.0069 13 0 0 0 2.49E+06 1.32E+06 - - - 4.5969 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.20312.20312.2 0.223 14-Aug K.QDILTIFK[136.11].R "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV8|B0QYV8_HUMAN" 2 984.5735 1.77 6893 20312 2 984.577529 493.294 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3764.7 - 1.22E+06 - - - 4.0586 - 1.504 0.262 - 177.8 1 2 0 0.004 8 0 0 0 2.71E+07 1.53E+07 - - - 2.2058 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20313.20313.2 0.0162 18/22 R.ALLANALTSALR[166.11].L "sp|P57088|TMM33_HUMAN,tr|D6RAA6|D6RAA6_HUMAN" 2 1222.7273 1.19 6894 20313 2 1222.729745 612.3709 Transmembrane protein 33 OS=Homo sapiens OX=9606 GN=TMEM33 PE=1 SV=2 9.79 3764.8 - 1.19E+06 - - - 2.007 - 2.544 0.302 - 1715.2 1 2 0 0.0025 12 0 0 0 2.12E+07 1.78E+07 - - - 3.7276 0.9968 230117_WJC_METTL3_WT_vs_EV_F01.20314.20314.2 1.38 12-Aug R.TLLEFLK[136.11].R "sp|Q14232|EI2BA_HUMAN,tr|F5H0D0|F5H0D0_HUMAN,tr|H0YGG4|H0YGG4_HUMAN" 3 870.5306 0.93 6895 20314 2 870.531822 436.2726 Translation initiation factor eIF-2B subunit alpha OS=Homo sapiens OX=9606 GN=EIF2B1 PE=1 SV=1 5.66 3764.9 - 838573 - - - 1.398 - 1.395 0.165 - 229.9 1 2 0 0.0012 7 0 0 0 1.52E+07 1.64E+07 - - - 1.3141 0.9942 230117_WJC_METTL3_WT_vs_EV_F01.20317.20317.2 0.0441 24-Aug R.GAAGALLVYDITR.R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1318.7245 2.7 6898 20317 2 1318.729208 660.3695 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3765.3 - 219807 - - - 3.5694 - 1.35 0.265 - 96 2 2 0 0.0047 13 0 0 0 2.66E+06 9.88E+05 - - - 1.6326 1 230117_WJC_METTL3_WT_vs_EV_F01.20318.20318.2 1.24E-08 13/28 R.VMAGALEGDIFIGPK.A "sp|P61163|ACTZ_HUMAN,sp|P42025|ACTY_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 4 1516.796 1.22 6899 20318 2 1516.798416 759.4053 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4.37 3765.4 - 183967 - - - 1.6251 - 2.524 0.526 - 475.2 1 2 0 0.0025 15 0 0 0 1.71E+06 1.40E+06 - - - 5.2015 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.20321.20321.2 0.565 20-Aug K.LFPGFEIETVK.N "sp|P08243|ASNS_HUMAN,tr|F8WEJ5|F8WEJ5_HUMAN" 2 1278.686 0.19 6901 20321 2 1278.687342 640.3503 Asparagine synthetase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=ASNS PE=1 SV=4 4.53 3765.9 - 234266 - - - 1.0573 - 1.304 0.199 - 134.6 1 2 0 0.0014 11 0 0 0 3.28E+06 1.71E+07 - - - 1.2285 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.20323.20323.2 5.44E-05 20-Nov R.ELGLGLGLGLK[136.11].E "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 1076.6685 1.03 6902 20323 2 1076.673448 539.3415 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 6.1 3766.1 - 3.28E+06 - - - 4.5994 - 2.056 0.421 - 320.8 1 2 0 0.005 11 0 0 0 1.28E+07 1.23E+07 - - - 4.0988 0.9954 230117_WJC_METTL3_WT_vs_EV_F01.20324.20324.2 4.55E-05 20-Nov R.ELGLGLGLGLK.E "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 1068.6543 0.96 6903 20324 2 1068.660763 535.3344 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 6.1 3766.2 - 3.48E+06 - - - 6.0515 - 1.723 0.469 - 298.3 1 2 0 0.0065 11 0 0 0 9.80E+06 1.02E+07 - - - 3.9748 1 230117_WJC_METTL3_WT_vs_EV_F01.20325.20325.3 2.59E-11 19/72 K.LGGSLADSYLDEGFLLDKK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2040.0415 2.94 6904 20325 3 2040.04527 681.0211 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.23 3766.3 - 1.65E+06 - - - 1.8294 - 4.254 0.631 - 609.8 1 2 0 0.0037 19 0 0 0 4.05E+06 1.38E+06 - - - 9.1311 0.9919 230117_WJC_METTL3_WT_vs_EV_F01.20326.20326.2 1.05 12-Jun R.IIWQFIK.E "sp|P48735|IDHP_HUMAN,tr|H0YL11|H0YL11_HUMAN" 2 946.564 2.65 6905 20326 2 946.564683 474.2893 "Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2" 8.75 3766.4 - 1.19E+06 - - - 0.6962 - 1.112 0.177 - 79.2 1 2 0 0.0007 7 0 0 0 6.57E+06 2.48E+06 - - - 0.6845 0.9953 230117_WJC_METTL3_WT_vs_EV_F01.20327.20327.2 0.181 18-Apr R.LFALVLTPTR.E sp|Q9H0S4|DDX47_HUMAN 1 1129.6859 1.25 6906 20327 2 1129.68907 565.8502 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 9.75 3766.5 - 1.06E+06 - - - 2.7795 - 1.357 0.283 - 30 20 2 0 0.0031 10 0 0 0 3.54E+06 2.83E+06 - - - 1.4012 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20329.20329.2 0.00899 18-Sep R.FC[160.03]IWTESAFR.K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1315.6019 0.92 6908 20329 2 1315.601911 658.8082 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3766.7 - 811932 - - - -0.0243 - 1.969 0.388 - 333.5 1 2 0 0 10 0 0 0 2.08E+07 2.26E+07 - - - 3.7979 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.20331.20331.2 0.181 18-Sep K.LGLFPSNFVK.E sp|Q9Y5K6|CD2AP_HUMAN 1 1120.6281 0.99 6910 20331 2 1120.628294 561.3213 CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1 8.75 3766.8 - 779957 - - - 0.1901 - 1.813 0.163 - 135 1 2 0 0.0002 10 0 0 0 8.49E+06 8.56E+06 - - - 1.9056 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.20334.20334.2 0.000221 20-Aug R.NFLSTPQFLYR.W "sp|Q9BUN8|DERL1_HUMAN,tr|E5RGY0|E5RGY0_HUMAN,tr|B4E1G1|B4E1G1_HUMAN" 3 1384.7139 0.79 6913 20334 2 1384.711713 693.3642 Derlin-1 OS=Homo sapiens OX=9606 GN=DERL1 PE=1 SV=1 8.75 3767.1 - 520321 - - - -1.6054 - 1.767 0.436 - 244.7 1 2 0 -0.0022 11 0 0 0 2.48E+06 3.12E+06 - - - 3.8006 1 230117_WJC_METTL3_WT_vs_EV_F01.20341.20341.2 0.000731 14/20 R.AFITNIPFDVK.W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1263.6863 2.57 6919 20341 2 1263.68859 632.8504 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3767.9 - 1.97E+07 - - - 1.7932 - 2.288 0.477 - 777.5 1 2 0 0.0023 11 0 0 0 1.15E+09 4.47E+08 - - - 4.8025 0.9551 230117_WJC_METTL3_WT_vs_EV_F01.20342.20342.2 0.00351 22-Sep K.AAAIGIDLGTTY.S "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1164.6027 - 6920 20342 2 1164.605296 583.3086 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 3.8 3768.1 - 1.96E+06 - - - 2.2686 - 1.841 0.357 - 298.6 1 1 0 0.0026 12 0 0 0 - - - - - 3.2828 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.20343.20343.3 0.00362 18/40 R.AALLELWELR[166.11]R[166.11].Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1388.8043 0.79 6921 20343 3 1388.811479 463.942 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.19 3768.2 - 1.68E+06 - - - 5.162 - 2.789 0.303 - 779.6 1 2 0 0.0072 11 0 0 0 7.17E+06 9.08E+06 - - - 4.83 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.20344.20344.2 0.00172 18-Nov K.LTLSALIDGK[136.11].N "sp|Q9Y277|VDAC3_HUMAN,sp|P21796|VDAC1_HUMAN" 2 1037.6212 2.83 6922 20344 2 1037.626355 519.8179 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.84 3768.3 - 1.61E+06 - - - 4.9575 - 2.282 0.309 - 307.6 1 2 0 0.0051 10 0 0 0 2.79E+08 9.88E+07 - - - 3.6246 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20345.20345.3 3.25E-05 17/40 R.AALLELWELRR.Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1368.7878 0.78 6923 20345 3 1368.79381 457.2699 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.19 3768.4 - 1.21E+06 - - - 4.4127 - 2.852 0.406 - 620.6 1 2 0 0.006 11 0 0 0 7.11E+06 9.08E+06 - - - 6.0421 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.20346.20346.2 0.0775 18-Sep R.LFALVLTPTR[166.11].E sp|Q9H0S4|DDX47_HUMAN 1 1139.6942 1.14 6924 20346 2 1139.700294 570.8544 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 9.75 3768.6 - 617254 - - - 5.347 - 2.156 0.4 - 248.4 1 2 0 0.0061 10 0 0 0 1.32E+07 1.16E+07 - - - 4.1379 1 230117_WJC_METTL3_WT_vs_EV_F01.20350.20350.2 1.70E-08 14/24 K.ILTFDQLALDSPK[136.11].G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1467.8064 0.74 6928 20350 2 1467.806006 734.9105 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3769.1 - 276390 - - - -0.2998 - 2.77 0.487 - 593.2 1 2 0 -0.0004 13 0 0 0 3.55E+08 4.83E+08 - - - 5.2527 0.9913 230117_WJC_METTL3_WT_vs_EV_F01.20352.20352.2 0.715 16-Oct R.ALQLLYDLR.Y "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1103.6339 1.29 6930 20352 2 1103.640451 552.8242 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.88 3769.4 - 202186 - - - 5.9404 - 2.07 0.232 - 278.5 1 2 0 0.0066 9 0 0 0 2.10E+07 1.63E+07 - - - 2.8573 0.9939 230117_WJC_METTL3_WT_vs_EV_F01.20353.20353.2 0.00436 12-Aug R.YGLVFFR.Q "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN,tr|F6WRY4|F6WRY4_HUMAN" 4 900.4858 1.1 6931 20353 2 900.490601 451.2502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.75 3769.5 - 190961 - - - 5.3604 - 1.747 0.273 - 204.3 1 2 0 0.0048 7 0 0 0 5.71E+06 5.21E+06 - - - 2.8236 1 230117_WJC_METTL3_WT_vs_EV_F01.20354.20354.2 6.59E-05 14/24 K.ILTFDQLALDSPK.G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1459.7922 -1 6932 20354 2 1459.797123 730.9034 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3769.6 - 182051 - - - 3.3409 - 2.716 0.525 - 665.8 1 2 0 0.0049 13 0 0 0 0.00E+00 0.00E+00 - - - 5.4815 0.9487 230117_WJC_METTL3_WT_vs_EV_F01.20356.20356.3 0.221 Jul-40 K.NAAIAVLEELK.K "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1169.6656 1.43 6934 20356 3 1169.671273 390.8958 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.53 3769.9 - 155633 - - - 4.8595 - 1.37 0.192 - 43.6 1 2 0 0.0057 11 0 0 0 1.29E+06 9.01E+05 - - - 1.5734 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.20362.20362.2 0.00654 18-Oct R.LTTLELLEVR[166.11].R "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1195.7052 0.79 6939 20362 2 1195.710458 598.8599 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.53 3770.6 - 4.39E+06 - - - 4.4317 - 2.006 0.387 - 343.7 1 2 0 0.0053 10 0 0 0 4.35E+07 5.50E+07 - - - 3.8409 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.20363.20363.3 0.00106 Dec-56 R.LFPLIQAMHPTLAGK.L "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 1635.9171 1.17 6940 20363 3 1635.924258 546.313 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.76 3770.7 - 266880 - - - 4.3945 - 2.195 0.38 - 127.5 1 2 0 0.0072 15 0 0 0 2.63E+06 2.25E+06 - - - 4.8261 1 230117_WJC_METTL3_WT_vs_EV_F01.20364.20364.2 0.0609 18-Dec R.FC[160.03]IWTESAFR[166.11].K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1325.6102 0.92 6941 20364 2 1325.613116 663.8124 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3770.8 - 3.37E+06 - - - 2.1899 - 2.347 0.535 - 576 1 2 0 0.0029 10 0 0 0 2.08E+07 2.26E+07 - - - 5.373 1 230117_WJC_METTL3_WT_vs_EV_F01.20365.20365.2 3.62E-05 18-Dec R.LTTLELLEVR.R "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1185.6969 0.71 6942 20365 2 1185.699606 593.8557 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.53 3770.8 - 3.30E+06 - - - 2.2915 - 2.46 0.478 - 613.8 1 2 0 0.0027 10 0 0 0 4.93E+07 6.94E+07 - - - 5.0833 1 230117_WJC_METTL3_WT_vs_EV_F01.20370.20370.2 1.67E-06 20-Nov R.FSYLAVIEGAK[136.11].F "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 1204.6583 2.46 6947 20370 2 1204.660146 603.3364 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 6 3771.2 - 1.17E+06 - - - 1.5116 - 2.06 0.557 - 329.8 1 2 0 0.0018 11 0 0 0 1.79E+07 7.25E+06 - - - 5.1095 0.9372 230117_WJC_METTL3_WT_vs_EV_F01.20371.20371.2 0.00889 16-Jun R.LFPLIQTMH.S "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 9 1098.5896 - 6948 20371 2 1098.591007 550.3021 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.74 3771.3 - 694559 - - - 1.2926 - 1.343 0.362 - 106.5 1 1 0 0.0014 9 0 0 0 - - - - - 2.5675 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.20372.20372.3 0.00292 Dec-40 R.LFDVLHEPFLK.V sp|P07992|ERCC1_HUMAN 1 1356.7442 3.52 6949 20372 3 1356.747582 453.2553 DNA excision repair protein ERCC-1 OS=Homo sapiens OX=9606 GN=ERCC1 PE=1 SV=1 5.32 3771.5 - 650609 - - - 2.5119 - 2.536 0.461 - 201.8 1 2 0 0.0034 11 0 0 0 2.80E+06 7.97E+05 - - - 6.3224 1 230117_WJC_METTL3_WT_vs_EV_F01.20373.20373.2 1.05E-06 22-Nov R.LFTNFSGADLLK[136.11].L "sp|Q12800|TFCP2_HUMAN,tr|F8VWL0|F8VWL0_HUMAN" 2 1332.7169 2.22 6950 20373 2 1332.719516 667.3657 Alpha-globin transcription factor CP2 OS=Homo sapiens OX=9606 GN=TFCP2 PE=1 SV=2 5.84 3771.6 - 626769 - - - 1.9607 - 2.389 0.581 - 328.5 1 2 0 0.0026 12 0 0 0 1.90E+07 8.53E+06 - - - 5.6229 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.20374.20374.2 0.00262 18-Oct R.EYLLDMIPPR.S "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 3 1245.6427 2.21 6951 20374 2 1245.647626 623.8286 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.37 3771.7 - 569410 - - - 3.9185 - 1.741 0.418 - 339.3 1 2 0 0.0049 10 0 0 0 1.31E+07 5.96E+06 - - - 3.6745 0.9647 230117_WJC_METTL3_WT_vs_EV_F01.20375.20375.2 1.13 20-Jul R.AALLELWELR[166.11]R[166.11].Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1388.8043 0.36 6952 20375 2 1388.807949 695.4094 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.19 3771.9 - 493196 - - - 2.6202 - 1.304 0.034 - 84.1 2 2 0 0.0036 11 0 0 0 4.88E+05 1.35E+06 - - - -0.1254 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.20376.20376.2 0.0029 20-Aug R.LYLQPWPVDVK.V "sp|Q9NWX5|ASB6_HUMAN,tr|F6TX30|F6TX30_HUMAN" 2 1356.7442 6.07 6953 20376 2 1356.74511 679.3794 Ankyrin repeat and SOCS box protein 6 OS=Homo sapiens OX=9606 GN=ASB6 PE=1 SV=1 5.83 3772 - 449830 - - - 0.6899 - 1.358 0.37 - 194.3 1 2 0 0.0009 11 0 0 0 9.43E+06 1.55E+06 - - - 2.6014 1 230117_WJC_METTL3_WT_vs_EV_F01.20380.20380.2 4.27E-05 22-Dec K.MFIGGLSWDTTK[136.11].K "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 1362.6733 1.11 6957 20380 2 1362.675513 682.3439 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 5.59 3772.5 - 392966 - - - 1.6071 - 2.153 0.488 - 384.5 1 2 0 0.0022 12 0 0 0 5.64E+07 5.08E+07 - - - 4.6624 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.20386.20386.2 1.07 14-Jul R.LLLTPWVK[136.11].F sp|Q14152|EIF3A_HUMAN 1 976.6201 0.88 6962 20386 2 976.6205 489.3173 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.75 3773.1 - 1.88E+06 - - - 0.4208 - 1.414 0.269 - 123.7 1 2 0 0.0004 8 0 0 0 3.09E+07 3.53E+07 - - - 2.0725 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.20387.20387.2 0.256 20-May R.VLPSIVNEVLK.S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1209.7333 1.37 6963 20387 2 1209.736816 605.8739 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3773.1 - 1.52E+06 - - - 2.9271 - 1.175 0.305 - 76.6 1 2 0 0.0035 11 0 0 0 1.36E+08 9.93E+07 - - - 1.7289 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20388.20388.2 9.00E-06 20-Oct R.FSYLAVIEGAK.F "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 1196.6441 2.42 6964 20388 2 1196.645421 599.3293 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 6 3773.1 - 1.17E+06 - - - 1.083 - 2.056 0.428 - 280 1 2 0 0.0013 11 0 0 0 1.79E+07 7.39E+06 - - - 4.1516 1 230117_WJC_METTL3_WT_vs_EV_F01.20390.20390.2 2.13E-05 13/24 R.PVGTSLFLQTALR.G sp|Q9H9S5|FKRP_HUMAN 1 1401.798 1 6966 20390 2 1401.799825 701.9063 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 10.18 3773.3 - 504488 - - - 1.3019 - 2.646 0.521 - 487.7 1 1 0 0.0018 13 0 0 0 7.91E+06 7.89E+06 - - - 5.3859 1 230117_WJC_METTL3_WT_vs_EV_F01.20391.20391.2 1.80E-06 28-Dec K.ELVGPPLAETVFTPK.T sp|P49792|RBP2_HUMAN 1 1596.8763 1.87 6967 20391 2 1596.877122 799.4454 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3773.3 - 370604 - - - 0.5085 - 2.315 0.568 - 415.1 1 2 0 0.0008 15 0 0 0 1.05E+07 5.61E+06 - - - 5.2997 1 230117_WJC_METTL3_WT_vs_EV_F01.20394.20394.2 6.86E-07 13/22 K.MFIGGLSWDTTK.K "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 1354.6591 1.11 6968 20394 2 1354.659648 678.3368 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 5.59 3773.7 - 2.52E+06 - - - 0.3876 - 2.231 0.594 - 454.9 1 2 0 0.0005 12 0 0 0 5.64E+07 5.08E+07 - - - 5.5395 1 230117_WJC_METTL3_WT_vs_EV_F01.20396.20396.2 0.00475 16/20 R.IPDQLVILDMK.H "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1283.7159 1.18 6970 20396 2 1283.71815 642.8652 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.21 3773.9 - 1.36E+06 - - - 1.7449 - 3.13 0.471 - 1397.3 1 2 0 0.0022 11 0 0 0 5.74E+07 4.85E+07 - - - 5.6059 1 230117_WJC_METTL3_WT_vs_EV_F01.20398.20398.2 0.00213 16/20 R.IPDQLVILDMK[136.11].H "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1291.7301 1.18 6972 20398 2 1291.726988 646.8723 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.21 3774.2 - 1.07E+06 - - - -2.4169 - 3.088 0.453 - 1180.4 1 2 0 -0.0031 11 0 0 0 5.74E+07 4.85E+07 - - - 5.4361 0.9946 230117_WJC_METTL3_WT_vs_EV_F01.20399.20399.2 0.00452 18-Sep R.ELIEMLAISR.N "sp|Q9NPJ6|MED4_HUMAN,tr|Q5T911|Q5T911_HUMAN" 2 1173.6427 2.02 6973 20399 2 1173.649365 587.8286 Mediator of RNA polymerase II transcription subunit 4 OS=Homo sapiens OX=9606 GN=MED4 PE=1 SV=1 4.53 3774.3 - 682401 - - - 5.6406 - 2.034 0.297 - 240.3 1 2 0 0.0066 10 0 0 0 6.85E+06 3.39E+06 - - - 3.2144 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20400.20400.2 0.00084 18-Oct K.LQDMLDGFIK.K "sp|P55010|IF5_HUMAN,tr|H0YM54|H0YM54_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YMJ8|H0YMJ8_HUMAN,tr|H0YN40|H0YN40_HUMAN" 5 1178.6005 1.31 6974 20400 2 1178.603106 590.3075 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 4.21 3774.5 - 563170 - - - 2.1721 - 2.068 0.407 - 201.6 1 2 0 0.0026 10 0 0 0 6.55E+06 5.00E+06 - - - 4.0744 1 230117_WJC_METTL3_WT_vs_EV_F01.20403.20403.2 5.06E-07 14/28 K.ELVGPPLAETVFTPK[136.11].T sp|P49792|RBP2_HUMAN 1 1604.8905 1.87 6977 20403 2 1604.891684 803.4525 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3774.9 - 257280 - - - 0.7315 - 2.346 0.566 - 448.3 1 2 0 0.0012 15 0 0 0 1.05E+07 5.61E+06 - - - 5.3175 1 230117_WJC_METTL3_WT_vs_EV_F01.20405.20405.2 2.32E-06 Nov-32 R.STGEAFVQFASQEIAEK.A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1840.8843 -1 6979 20405 2 1840.889686 921.4494 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3775.1 - 197028 - - - 2.9209 - 2.6 0.576 - 302.1 1 2 0 0.0054 17 0 0 0 0.00E+00 0.00E+00 - - - 5.6428 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20410.20410.2 1.28E-05 30-Dec R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 59.01 6983 20410 2 1549.883781 775.9487 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3775.8 - 411908 - - - 0.6381 - 2.256 0.447 - 465.7 1 2 0 0.001 16 0 0 0 6.42E+06 1.09E+05 - - - 4.3425 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20412.20412.2 0.000267 14-Aug R.FSLDFNLR.T "sp|Q96MM3|ZFP42_HUMAN,sp|P25490|TYY1_HUMAN,sp|O15391|TYY2_HUMAN,tr|H0YJV7|H0YJV7_HUMAN" 4 1010.5185 2.09 6984 20412 2 1010.518841 506.2665 Zinc finger protein 42 homolog OS=Homo sapiens OX=9606 GN=ZFP42 PE=1 SV=2 5.84 3776 - 5.01E+06 - - - 0.3068 - 1.801 0.411 - 210.4 1 2 0 0.0003 8 0 0 0 1.76E+07 8.40E+06 - - - 3.851 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.20413.20413.2 0.000321 14-Aug R.DWVLNEFR[166.11].S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1087.5326 1.12 6985 20413 2 1087.53337 544.7736 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3776.1 - 3.71E+06 - - - 0.6952 - 1.804 0.307 - 370.1 1 2 0 0.0008 8 0 0 0 2.53E+07 2.27E+07 - - - 3.0877 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.20415.20415.2 0.000626 13/24 R.LAALPNVYEVISK.S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1415.8024 2.42 6987 20415 2 1415.806834 708.9085 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3776.2 - 5.14E+06 - - - 3.1198 - 2.381 0.332 - 449.3 1 2 0 0.0044 13 0 0 0 1.50E+07 6.17E+06 - - - 3.7183 1 230117_WJC_METTL3_WT_vs_EV_F01.20428.20428.2 8.82E-05 16-Sep K.FPEILATLR.G sp|P54198|HIRA_HUMAN 1 1058.6124 3.07 7000 20428 2 1058.612648 530.3135 Protein HIRA OS=Homo sapiens OX=9606 GN=HIRA PE=1 SV=2 6 3777.7 - 1.22E+06 - - - 0.205 - 2.051 0.475 - 231.5 1 2 0 0.0002 9 0 0 0 3.64E+06 1.19E+06 - - - 4.6274 1 230117_WJC_METTL3_WT_vs_EV_F01.20430.20430.2 2.35E-10 15/36 R.YEGILYTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2100.0627 -1 7002 20430 2 2100.061686 1051.0386 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3777.9 - 1.03E+06 - - - -0.4671 - 3.103 0.644 - 403.6 1 2 0 -0.001 19 0 0 0 0.00E+00 0.00E+00 - - - 6.5813 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.20431.20431.3 0.0226 Dec-40 K.LLPQFLLHLDK[136.11].L "sp|Q8N4J0|CARME_HUMAN,tr|Q5T8V1|Q5T8V1_HUMAN,tr|Q5T8U9|Q5T8U9_HUMAN" 3 1343.8057 1.37 7003 20431 3 1343.807034 448.9425 Carnosine N-methyltransferase OS=Homo sapiens OX=9606 GN=CARNMT1 PE=1 SV=1 6.74 3778.1 - 981569 - - - 1.024 - 2.178 0.343 - 183.6 1 2 0 0.0014 11 0 0 0 3.04E+06 2.22E+06 - - - 4.5751 0.9765 230117_WJC_METTL3_WT_vs_EV_F01.20433.20433.2 3.29 16-Sep R.ALQLLYDLR[166.11].Y "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1113.6422 1.29 7004 20433 2 1113.642674 557.8284 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.88 3778.3 - 282031 - - - 0.4571 - 1.334 0.018 - 144.4 1 2 0 0.0005 9 0 0 0 2.10E+07 1.63E+07 - - - 0.0075 1 230117_WJC_METTL3_WT_vs_EV_F01.20434.20434.2 5.80E-13 18/36 R.YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2108.0769 -1 7005 20434 2 2108.089413 1055.0457 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3778.4 - 81567.9 - - - 5.9514 - 3.438 0.671 - 868.5 1 2 0 0.0125 19 0 0 0 0.00E+00 0.00E+00 - - - 7.0291 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20436.20436.2 0.00105 14-Aug R.DWVLNEFR.S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1077.5243 1.12 7007 20436 2 1077.526954 539.7694 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3778.5 - 3.64E+06 - - - 2.4222 - 1.828 0.402 - 369.9 1 2 0 0.0026 8 0 0 0 2.53E+07 2.27E+07 - - - 3.8286 0.9949 230117_WJC_METTL3_WT_vs_EV_F01.20439.20439.2 0.0674 12-Aug R.FVFLLDR.G sp|Q13045|FLII_HUMAN 1 908.512 1.97 7010 20439 2 908.513442 455.2633 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3778.8 - 1.02E+06 - - - 1.5993 - 1.578 0.065 - 252.8 1 2 0 0.0015 7 0 0 0 1.15E+07 5.83E+06 - - - 0.966 0.9964 230117_WJC_METTL3_WT_vs_EV_F01.20441.20441.2 0.335 16-Sep K.LGFMSAFVK.A "sp|P36957|ODO2_HUMAN,tr|Q86SW4|Q86SW4_HUMAN" 2 998.5259 1.04 7012 20441 2 998.52733 500.2702 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 8.75 3779 - 823207 - - - 1.4081 - 1.318 0.187 - 142.6 1 2 0 0.0014 9 0 0 0 4.30E+06 4.15E+06 - - - 1.2206 0.9942 230117_WJC_METTL3_WT_vs_EV_F01.20444.20444.2 0.0106 12-Jul R.FVFLLDR[166.11].G sp|Q13045|FLII_HUMAN 1 918.5203 -1 7015 20444 2 918.52112 460.2674 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3779.4 - 696722 - - - 0.9374 - 1.481 0.081 - 195.7 1 2 0 0.0009 7 0 0 0 0.00E+00 0.00E+00 - - - 0.8833 1 230117_WJC_METTL3_WT_vs_EV_F01.20448.20448.2 2.94E-06 16/26 K.LLAESVTEVEIFGK.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1533.829 -1 7019 20448 2 1533.831604 767.9218 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 3779.9 - 402648 - - - 1.6808 - 3.209 0.537 - 810.5 1 2 0 0.0026 14 0 0 0 0.00E+00 0.00E+00 - - - 5.9324 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.20460.20460.2 0.000626 16-Nov K.QVDLIDLVR.W sp|Q9UKN8|TF3C4_HUMAN 1 1069.6132 -1 7030 20460 2 1069.61723 535.8139 General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2 4.21 3781.5 - 509193 - - - 3.806 - 2.18 0.319 - 438.3 1 2 0 0.0041 9 0 0 0 0.00E+00 0.00E+00 - - - 3.6505 0.9934 230117_WJC_METTL3_WT_vs_EV_F01.20463.20463.2 0.00902 16-Aug R.DSVVLSLLK[136.11].Q sp|O43264|ZW10_HUMAN 1 980.5997 1.21 7033 20463 2 980.601839 491.3072 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 5.84 3781.9 - 293056 - - - 2.1324 - 1.565 0.073 - 138.2 1 2 0 0.0021 9 0 0 0 4.83E+06 3.99E+06 - - - 0.8753 0.9837 230117_WJC_METTL3_WT_vs_EV_F01.20464.20464.2 0.0701 18-Sep K.NGFLLDGFPR.T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1134.5822 15.6 7034 20464 2 1134.585737 568.2984 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3782.1 - 266859 - - - 3.1227 - 1.155 0.157 - 130.7 1 2 0 0.0035 10 0 0 0 8.99E+06 5.77E+05 - - - 0.6017 0.9851 230117_WJC_METTL3_WT_vs_EV_F01.20469.20469.2 0.00324 18-Aug R.VLQDFYLELR[166.11].K "sp|Q9UJA3|MCM8_HUMAN,tr|A0A494C100|A0A494C100_HUMAN" 2 1304.7004 -1 7039 20469 2 1304.70967 653.3575 DNA helicase MCM8 OS=Homo sapiens OX=9606 GN=MCM8 PE=1 SV=2 4.37 3782.7 - 145177 - - - 7.0989 - 1.711 0.346 - 217.8 1 2 0 0.0093 10 0 0 0 0.00E+00 0.00E+00 - - - 3.0928 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20478.20478.2 0.000371 18-Nov K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.71 7047 20478 2 1168.708521 585.3606 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3783.7 - 2.20E+06 - - - 1.5367 - 2.244 0.406 - 349.3 1 2 0 0.0018 10 0 0 0 9.85E+09 5.76E+09 - - - 4.2953 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20479.20479.2 0.0106 18-Nov K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.71 7048 20479 2 1176.722339 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3783.7 - 1.84E+06 - - - 1.2016 - 2.217 0.346 - 361.6 1 2 0 0.0014 10 0 0 0 9.85E+09 5.76E+09 - - - 3.8184 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20480.20480.2 0.279 18-Dec R.VDILDPALLR[166.11].S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1133.6684 1.99 7049 20480 2 1133.670045 567.8415 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3783.7 - 1.58E+06 - - - 1.4687 - 2.435 0.332 - 451.6 1 2 0 0.0017 10 0 0 0 2.44E+08 1.22E+08 - - - 3.9767 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20481.20481.2 0.00883 18-Oct K.DFLLQQTMLR[166.11].V sp|Q04760|LGUL_HUMAN 1 1273.6728 1.15 7050 20481 2 1273.673543 637.8437 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 5.84 3783.8 - 456767 - - - 0.5731 - 2.086 0.334 - 496.2 1 2 0 0.0007 10 0 0 0 1.92E+07 1.67E+07 - - - 3.56 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.20482.20482.2 0.00637 14-Sep R.LFSWLVNR.L "sp|O43795|MYO1B_HUMAN,sp|Q8WXR4|MYO3B_HUMAN,tr|F5H2J1|F5H2J1_HUMAN,tr|A0A0U1RRI3|A0A0U1RRI3_HUMAN,tr|E9PDF6|E9PDF6_HUMAN" 5 1033.5709 1.16 7051 20482 2 1033.571896 517.7927 Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3 9.75 3783.9 - 373579 - - - 0.9627 - 1.881 0.287 - 236.1 1 2 0 0.001 8 0 0 0 3.21E+06 2.76E+06 - - - 3.066 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.20483.20483.2 7.12E-05 12-Sep R.YMDLLWR.Y "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 995.4899 1.44 7052 20483 2 995.491478 498.7522 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 5.84 3784 - 347419 - - - 1.6123 - 1.483 0.374 - 248.1 1 2 0 0.0016 7 0 0 0 4.86E+06 3.38E+06 - - - 3.0515 0.9973 230117_WJC_METTL3_WT_vs_EV_F01.20485.20485.2 0.00317 18-Oct K.NGFLLDGFPR[166.11].T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1144.5905 1.23 7054 20485 2 1144.595868 573.3025 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3784.2 - 310439 - - - 4.7213 - 1.682 0.385 - 276.5 1 2 0 0.0054 10 0 0 0 1.31E+07 1.06E+07 - - - 3.3343 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.20486.20486.3 7.94E-06 17/48 R.WLPLGLGLNHLGK.G "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1416.8242 2.58 7055 20486 3 1416.825452 473.282 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 8.76 3784.3 - 259809 - - - 0.9154 - 2.98 0.389 - 410.3 1 2 0 0.0013 13 0 0 0 9.38E+06 3.64E+06 - - - 5.8371 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20489.20489.2 0.000111 14-Aug R.GFC[160.03]FITFK[136.11].E "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1026.5088 1.12 7057 20489 2 1026.510013 514.2617 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.22 3784.6 - 5.78E+07 - - - 1.1583 - 1.542 0.543 - 250.6 1 2 0 0.0012 8 0 0 0 2.13E+08 1.89E+08 - - - 4.3574 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20490.20490.2 0.000138 18-Sep K.LVFPQDLLEK.G "sp|Q8TCT9|HM13_HUMAN,tr|A0A3B3IT72|A0A3B3IT72_HUMAN,tr|A0A0S2Z6F0|A0A0S2Z6F0_HUMAN,tr|A0A3B3IUB5|A0A3B3IUB5_HUMAN,tr|A0A075B6F6|A0A075B6F6_HUMAN" 5 1200.6754 1.86 7058 20490 2 1200.677464 601.345 Minor histocompatibility antigen H13 OS=Homo sapiens OX=9606 GN=HM13 PE=1 SV=1 4.37 3784.7 - 2.15E+06 - - - 1.6982 - 1.692 0.411 - 204.5 1 2 0 0.002 10 0 0 0 1.52E+07 8.19E+06 - - - 3.544 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20491.20491.2 0.0654 18-Aug R.VDILDPALLR.S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1123.6601 1.99 7059 20491 2 1123.661252 562.8373 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3784.7 - 2.44E+07 - - - 1.0163 - 1.979 0.369 - 206.5 1 2 0 0.0011 10 0 0 0 2.44E+08 1.22E+08 - - - 3.6714 0.995 230117_WJC_METTL3_WT_vs_EV_F01.20492.20492.2 0.113 14-Jul R.YLIYDIIK.F sp|O60942|MCE1_HUMAN 1 1039.5954 5.09 7060 20492 2 1039.594468 520.805 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 5.83 3784.8 - 3.47E+06 - - - -0.8811 - 1.218 0.283 - 151.9 1 2 0 -0.0009 8 0 0 0 2.76E+07 5.42E+06 - - - 1.7257 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20493.20493.2 0.000988 18-Oct R.GLAVFISDIR[166.11].N "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|M0R2D9|M0R2D9_HUMAN,tr|E9PR62|E9PR62_HUMAN" 4 1099.6265 1.74 7061 20493 2 1099.627007 550.8205 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 5.84 3784.8 - 2.53E+06 - - - 0.4474 - 2.053 0.423 - 496.8 1 2 0 0.0005 10 0 0 0 2.52E+07 1.45E+07 - - - 4.1729 1 230117_WJC_METTL3_WT_vs_EV_F01.20495.20495.2 1.83E-07 13/26 K.GLIGNLYLNDSPLK[136.11].N sp|Q8IW92|GLBL2_HUMAN 1 1523.8439 0.76 7063 20495 2 1523.848169 762.9292 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 5.83 3784.9 - 1.39E+06 - - - 2.8054 - 2.78 0.578 - 722.5 1 2 0 0.0043 14 0 0 0 7.79E+06 1.02E+07 - - - 5.8746 1 230117_WJC_METTL3_WT_vs_EV_F01.20496.20496.2 4.52E-07 13/26 K.GLIGNLYLNDSPLK.N sp|Q8IW92|GLBL2_HUMAN 1 1515.8297 0.76 7064 20496 2 1515.832392 758.9221 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 5.83 3785 - 1.32E+06 - - - 1.7799 - 2.626 0.549 - 385.4 1 2 0 0.0027 14 0 0 0 7.79E+06 1.02E+07 - - - 5.5178 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20497.20497.2 0.000446 18-Sep R.TLVEDLFADK.H "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1149.5918 1.69 7065 20497 2 1149.593845 575.8032 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.03 3785.1 - 1.32E+06 - - - 1.818 - 1.909 0.369 - 185.2 1 2 0 0.0021 10 0 0 0 4.32E+07 2.56E+07 - - - 3.5706 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.20499.20499.2 0.0958 20-May K.GMDVYGYLLAR.E sp|Q9UJX3|APC7_HUMAN 1 1256.6223 3.05 7067 20499 2 1256.624862 629.3184 Anaphase-promoting complex subunit 7 OS=Homo sapiens OX=9606 GN=ANAPC7 PE=1 SV=4 5.83 3785.3 - 801199 - - - 2.0038 - 1.128 0.304 - 84.8 1 2 0 0.0025 11 0 0 0 2.14E+06 7.00E+05 - - - 1.6114 1 230117_WJC_METTL3_WT_vs_EV_F01.20504.20504.2 1.11E-06 13/22 R.GNSIIMLEALER.V "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1344.7071 1.26 7070 20504 2 1344.708832 673.3608 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3785.9 - 8.80E+06 - - - 1.2612 - 2.638 0.522 - 762.3 1 2 0 0.0017 12 0 0 0 6.15E+07 4.89E+07 - - - 5.4482 0.999 230117_WJC_METTL3_WT_vs_EV_F01.20506.20506.2 0.0202 20-Dec R.LEYC[160.03]EALAMLR.E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1367.6577 1.62 7072 20506 2 1367.656142 684.8361 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3786.1 - 6.05E+06 - - - -1.1706 - 2.291 0.369 - 620.2 1 2 0 -0.0016 11 0 0 0 2.44E+07 1.51E+07 - - - 4.0085 1 230117_WJC_METTL3_WT_vs_EV_F01.20507.20507.2 0.00171 20-Dec R.LEYC[160.03]EALAMLR[166.11].E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1377.666 1.62 7073 20507 2 1377.663975 689.8403 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3786.1 - 4.72E+06 - - - -1.4793 - 2.532 0.502 - 783.8 1 2 0 -0.002 11 0 0 0 2.44E+07 1.51E+07 - - - 5.2613 1 230117_WJC_METTL3_WT_vs_EV_F01.20509.20509.2 3.30E-06 17/34 K.IAIIGAGIGGTSAAYYLR.Q "sp|Q9UHG3|PCYOX_HUMAN,tr|F8W8W4|F8W8W4_HUMAN" 2 1765.9727 2.2 7075 20509 2 1765.972715 883.9936 Prenylcysteine oxidase 1 OS=Homo sapiens OX=9606 GN=PCYOX1 PE=1 SV=3 8.59 3786.3 - 3.13E+06 - - - 0.0255 - 3.198 0.466 - 833.5 1 2 0 0 18 0 0 0 8.27E+06 3.76E+06 - - - 5.341 0.9965 230117_WJC_METTL3_WT_vs_EV_F01.20510.20510.2 0.000924 22-Oct R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 2671.91 7076 20510 2 1603.758247 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3786.4 - 2.73E+06 - - - -3.5498 - 1.974 0.499 - 280.3 1 2 0 -0.0057 12 0 0 0 1.28E+10 4.81E+06 - - - 4.5142 0.9773 230117_WJC_METTL3_WT_vs_EV_F01.20511.20511.2 0.716 14-Jun -.MLPLSLLK.T "sp|Q9Y4Z0|LSM4_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 913.5671 2.25 7077 20511 2 913.566265 457.7908 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 8.5 3786.4 - 2.44E+06 - - - -0.8713 - 1.067 0.175 - 121.3 1 2 0 -0.0008 8 0 0 0 1.24E+07 5.53E+06 - - - 0.5289 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.20512.20512.3 0.029 Nov-36 K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.62 7078 20512 3 1168.705243 390.5762 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3786.5 - 2.24E+06 - - - -1.2681 - 2.088 0.343 - 150.6 1 2 0 -0.0015 10 0 0 0 4.76E+07 2.94E+07 - - - 4.5137 0.9642 230117_WJC_METTL3_WT_vs_EV_F01.20513.20513.2 0.0653 16-Nov L.PSIVNEVLK.S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 997.5808 2.08 7079 20513 2 997.582419 499.7977 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 6.43 3786.6 - 2.10E+06 - - - 1.6259 - 2.21 0.273 - 325.7 1 1 0 0.0016 9 0 0 0 3.88E+06 1.87E+06 - - - 3.351 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20514.20514.2 1.49E-05 13/34 K.IAIIGAGIGGTSAAYYLR[166.11].Q "sp|Q9UHG3|PCYOX_HUMAN,tr|F8W8W4|F8W8W4_HUMAN" 2 1775.9809 -1 7080 20514 2 1775.982982 888.9977 Prenylcysteine oxidase 1 OS=Homo sapiens OX=9606 GN=PCYOX1 PE=1 SV=3 8.59 3786.7 - 1.83E+06 - - - 1.1498 - 2.472 0.448 - 458 1 2 0 0.002 18 0 0 0 0.00E+00 0.00E+00 - - - 4.5743 0.9756 230117_WJC_METTL3_WT_vs_EV_F01.20515.20515.2 0.0216 16-Dec L.PSIVNEVLK[136.11].S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1005.595 -1 7081 20515 2 1005.596125 503.8048 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 6.43 3786.8 - 1.22E+06 - - - 1.1217 - 2.292 0.35 - 383.8 1 1 0 0.0011 9 0 0 0 0.00E+00 0.00E+00 - - - 4.0253 1 230117_WJC_METTL3_WT_vs_EV_F01.20516.20516.2 0.183 16/28 R.LLAEIGAVTLVSAPR.P "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1508.8926 87.93 7082 20516 2 1508.89219 755.4536 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 6 3787 - 1.15E+06 - - - -0.2909 - 2.964 0.441 - 910.7 1 1 0 -0.0004 15 0 0 0 3.13E+06 3.56E+04 - - - 4.9694 0.9882 230117_WJC_METTL3_WT_vs_EV_F01.20517.20517.2 2.27 14-Jul R.SGLLGELR.N "sp|O60336|MABP1_HUMAN,tr|D6RHX7|D6RHX7_HUMAN" 2 843.4814 23.71 7083 20517 2 843.481677 422.748 Mitogen-activated protein kinase-binding protein 1 OS=Homo sapiens OX=9606 GN=MAPKBP1 PE=1 SV=4 5.72 3787.1 - 1.11E+06 - - - 0.3082 - 1.386 0.067 - 156 1 2 0 0.0003 8 0 0 0 2.11E+07 8.89E+05 - - - 0.5203 1 230117_WJC_METTL3_WT_vs_EV_F01.20519.20519.2 0.000763 22-Oct R.DLAQDEAVWLER[166.11].G "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1453.7077 -1 7085 20519 2 1453.703654 727.8611 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 3.92 3787.3 - 603063 - - - -2.7681 - 2.174 0.494 - 269.3 1 2 0 -0.004 12 0 0 0 0.00E+00 0.00E+00 - - - 4.7317 0.999 230117_WJC_METTL3_WT_vs_EV_F01.20522.20522.2 0.00324 14-Sep K.QFLPFLQR[166.11].A "sp|Q7KZF4|SND1_HUMAN,tr|H7C597|H7C597_HUMAN" 2 1057.5948 1.12 7087 20522 2 1057.594063 529.8047 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 9.75 3787.5 - 657818 - - - -0.7167 - 1.912 0.324 - 274.8 1 2 0 -0.0008 8 0 0 0 3.20E+07 2.86E+07 - - - 3.3886 1 230117_WJC_METTL3_WT_vs_EV_F01.20523.20523.3 3.90E-06 13/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 3363.17 7088 20523 3 1603.767106 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3787.6 - 1.52E+06 - - - 1.9741 - 2.401 0.554 - 239 1 2 0 0.0032 12 0 0 0 1.56E+09 4.63E+05 - - - 7.1435 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20533.20533.2 4.13E-05 22-Sep R.LLVFGGMVEYGK[136.11].Y "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 1319.7039 2.4 7094 20533 2 1319.706806 660.8592 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 6 3788.7 - 953832 - - - 2.2058 - 1.802 0.512 - 221.9 1 2 0 0.0029 12 0 0 0 8.34E+06 3.47E+06 - - - 4.3712 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.20542.20542.2 0.00111 24-Dec R.LAAVALINAAIQK[136.11].G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1302.8115 1.07 7099 20542 2 1302.810248 652.413 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3789.8 - 5.36E+06 - - - -0.9395 - 2.561 0.424 - 484.1 1 2 0 -0.0012 13 0 0 0 1.98E+07 1.84E+07 - - - 4.5858 1 230117_WJC_METTL3_WT_vs_EV_F01.20551.20551.2 8.55E-06 16/24 R.LAAVALINAAIQK.G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1294.7973 1.1 7106 20551 2 1294.795117 648.4059 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3790.7 - 0 - - - -1.6644 - 3.317 0.355 - 935.2 1 2 0 -0.0022 13 0 0 0 2.02E+07 1.84E+07 - - - 4.7398 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20554.20554.2 0.00018 14-Aug R.GFC[160.03]FITFK.E "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1018.4946 1.12 7109 20554 2 1018.495465 510.2546 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.22 3791.1 - 320136 - - - 0.8257 - 1.567 0.475 - 248.9 1 2 0 0.0008 8 0 0 0 2.13E+08 1.89E+08 - - - 3.9037 0.8549 230117_WJC_METTL3_WT_vs_EV_F01.20556.20556.2 0.0127 12-Jun R.TFHIFYY.M "sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 3 989.4647 - 7111 20556 2 989.465284 495.7396 Myosin-11 OS=Homo sapiens OX=9606 GN=MYH11 PE=1 SV=3 6.4 3791.3 - 250988 - - - 0.5862 - 1.096 0.331 - 123 1 1 0 0.0006 7 0 0 0 - - - - - 1.776 1 230117_WJC_METTL3_WT_vs_EV_F01.20560.20560.2 1.61E-11 15/24 R.WSTLVEDYGMELR.K sp|O00232|PSD12_HUMAN 1 1597.7446 0.14 7115 20560 2 1597.744209 799.8796 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.14 3791.9 - 73347.6 - - - -0.2723 - 3.008 0.654 - 936.3 1 2 0 -0.0004 13 0 0 0 8.98E+06 6.50E+07 - - - 6.6978 1 230117_WJC_METTL3_WT_vs_EV_F01.20570.20570.2 5.55E-06 15/24 R.TLVSGLLLEDSVR.V sp|A0A2Z4LIS9|FXO3B_HUMAN 1 1400.7875 -1 7123 20570 2 1400.785323 701.401 Forkhead box protein O3B OS=Homo sapiens OX=9606 GN=FOXO3B PE=1 SV=1 4.37 3793 - 481557 - - - -1.5506 - 2.309 0.52 - 388.3 1 2 0 -0.0022 13 0 0 0 0.00E+00 0.00E+00 - - - 5.0287 1 230117_WJC_METTL3_WT_vs_EV_F01.20571.20571.2 0.000267 13/20 K.SIDPALSMLIK[136.11].S sp|Q9H501|ESF1_HUMAN 1 1194.6773 1.07 7124 20571 2 1194.675176 598.3459 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 5.55 3793.2 - 412151 - - - -1.8164 - 2.231 0.504 - 396 1 2 0 -0.0022 11 0 0 0 8.05E+06 7.50E+06 - - - 4.9337 1 230117_WJC_METTL3_WT_vs_EV_F01.20572.20572.2 1.03E-05 20-Dec K.SIDPALSMLIK.S sp|Q9H501|ESF1_HUMAN 1 1186.6631 1.07 7125 20572 2 1186.657143 594.3388 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 5.55 3793.3 - 410127 - - - -5.0587 - 2.303 0.492 - 335.5 1 2 0 -0.006 11 0 0 0 8.05E+06 7.50E+06 - - - 4.9298 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.20576.20576.2 0.00359 24-Oct K.C[160.03]LAPTYLGEFSLR.G "sp|P49366|DHYS_HUMAN,tr|Q5J8M5|Q5J8M5_HUMAN,tr|M0R264|M0R264_HUMAN,tr|A0A087WZK0|A0A087WZK0_HUMAN,tr|M0R1T2|M0R1T2_HUMAN" 5 1525.7599 1.4 7129 20576 2 1525.76578 763.8872 Deoxyhypusine synthase OS=Homo sapiens OX=9606 GN=DHPS PE=1 SV=1 5.99 3793.8 - 339723 - - - 3.8538 - 1.81 0.363 - 330.8 1 2 0 0.0059 13 0 0 0 4.42E+06 3.16E+06 - - - 3.2431 0.9419 230117_WJC_METTL3_WT_vs_EV_F01.20580.20580.3 1.15 Nov-48 R.LAAVALINAAIQK[136.11].G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1302.8115 2.46 7133 20580 3 1302.810744 435.2778 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3794.4 - 198304 - - - -0.5588 - 1.393 0.12 - 157.7 1 2 0 -0.0007 13 0 0 0 4.55E+06 1.85E+06 - - - 0.7764 1 230117_WJC_METTL3_WT_vs_EV_F01.20581.20581.2 3.80E-06 13/22 R.IMVANIEEVLQR[166.11].G "sp|O75396|SC22B_HUMAN,tr|A0A087X1A9|A0A087X1A9_HUMAN" 2 1423.7733 4.65 7134 20581 2 1423.763753 712.8939 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 4.53 3794.5 - 167034 - - - -6.6738 - 2.616 0.484 - 721.8 1 2 0 -0.0095 12 0 0 0 1.04E+07 2.24E+06 - - - 5.1431 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.20582.20582.3 0.00445 Dec-48 K.LYGLLDPSVFHVK[136.11].Y sp|Q9BVI4|NOC4L_HUMAN 1 1494.8326 1.21 7135 20582 3 1494.832683 499.2848 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.74 3794.6 - 154321 - - - 0.0549 - 2.608 0.424 - 184.8 1 2 0 0.0001 13 0 0 0 3.15E+06 2.61E+06 - - - 5.8662 0.9849 230117_WJC_METTL3_WT_vs_EV_F01.20583.20583.3 0.145 Oct-48 K.LYGLLDPSVFHVK.Y sp|Q9BVI4|NOC4L_HUMAN 1 1486.8184 1.21 7136 20583 3 1486.815448 496.6134 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.74 3794.7 - 135355 - - - -1.9861 - 1.512 0.248 - 48.8 2 2 0 -0.003 13 0 0 0 3.15E+06 2.61E+06 - - - 2.2858 0.9921 230117_WJC_METTL3_WT_vs_EV_F01.20586.20586.2 0.0192 20-Jun K.VFLGNVETFIK[136.11].Q "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHA0|A0A6Q8PHA0_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF69|A0A6Q8PF69_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PGR0|A0A6Q8PGR0_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN,tr|A0A6Q8PFN8|A0A6Q8PFN8_HUMAN" 16 1273.7162 1.32 7138 20586 2 1273.715979 637.8654 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 5.97 3795 - 1.13E+06 - - - -0.1531 - 1.31 0.182 - 80.1 2 2 0 -0.0002 11 0 0 0 4.49E+07 3.41E+07 - - - 0.9812 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20587.20587.2 0.0488 16-Aug K.EIIDLVLDR[166.11].L "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 9 1094.6211 3.2 7139 20587 2 1094.622628 548.3178 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.03 3795.1 - 6.84E+06 - - - 1.4005 - 1.836 0.321 - 281 1 2 0 0.0015 9 0 0 0 5.52E+08 1.72E+08 - - - 3.1692 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.20588.20588.2 0.000579 16-Sep K.ELALSALLK[136.11].F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 964.6048 0.96 7140 20588 2 964.60434 483.3097 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3795.1 - 5.29E+06 - - - -0.5111 - 1.767 0.368 - 287.6 1 2 0 -0.0005 9 0 0 0 3.88E+07 4.06E+07 - - - 3.4059 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.20589.20589.2 0.00121 16-Sep K.ELALSALLK.F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 956.5906 0.96 7141 20589 2 956.589521 479.3026 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3795.2 - 5.00E+06 - - - -1.1625 - 1.819 0.368 - 263 1 2 0 -0.0011 9 0 0 0 3.88E+07 4.06E+07 - - - 3.4896 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.20591.20591.2 0.00493 12-Jul R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 57.25 7143 20591 2 808.432616 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 3795.3 - 2.28E+06 - - - -0.5616 - 1.664 0.286 - 125.6 1 2 0 -0.0005 7 0 0 0 1.30E+07 2.27E+05 - - - 2.7668 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.20593.20593.2 0.0022 18-Aug K.INEWLTLVEK.E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1243.6812 0.99 7145 20593 2 1243.680206 622.8479 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.53 3795.4 - 2.08E+06 - - - -0.8306 - 1.94 0.384 - 190.3 1 2 0 -0.001 10 0 0 0 1.75E+07 1.76E+07 - - - 3.7267 1 230117_WJC_METTL3_WT_vs_EV_F01.20596.20596.2 2.63E-11 15/24 R.WSTLVEDYGMELR.K sp|O00232|PSD12_HUMAN 1 1597.7446 0.14 7148 20596 2 1597.745001 799.8796 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.14 3795.6 - 1.59E+06 - - - 0.2234 - 2.742 0.678 - 887.6 1 2 0 0.0004 13 0 0 0 8.98E+06 6.50E+07 - - - 6.6374 1 230117_WJC_METTL3_WT_vs_EV_F01.20597.20597.2 3.04E-07 18-Sep K.GPDWILGEIK.T "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 6 1126.6023 2.22 7149 20597 2 1126.599681 564.3084 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 4.37 3795.7 - 1.41E+06 - - - -2.2892 - 2.032 0.487 - 368.1 1 2 0 -0.0026 10 0 0 0 1.04E+07 4.70E+06 - - - 4.6163 1 230117_WJC_METTL3_WT_vs_EV_F01.20598.20598.2 6.44E-07 18/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 7150 20598 2 1343.614916 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3795.8 - 1.23E+06 - - - 2.5707 - 2.979 0.53 - 1268.2 1 1 0 0.0035 10 0 0 0 5.23E+07 0.00E+00 - - - 6.0014 0.9759 230117_WJC_METTL3_WT_vs_EV_F01.20599.20599.2 0.197 18-Jul K.GPDWILGEIK.T "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 6 1126.6023 2.22 7151 20599 2 1126.599681 564.3084 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 4.37 3795.9 - 1.41E+06 - - - -2.2892 - 1.355 0.171 - 141.4 1 2 0 -0.0026 10 0 0 0 1.04E+07 4.70E+06 - - - 1.1512 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20601.20601.2 0.000989 14-Aug R.LMLLESWR.S "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 1046.5583 0.72 7153 20601 2 1046.559354 524.2864 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 6 3796 - 979481 - - - 1.0195 - 1.698 0.423 - 233.5 1 2 0 0.0011 8 0 0 0 4.81E+06 6.63E+06 - - - 3.7617 1 230117_WJC_METTL3_WT_vs_EV_F01.20602.20602.2 1.82E-09 20-Nov K.C[160.03]GPMVLDALIK.L "sp|P21912|SDHB_HUMAN,tr|A0A087WWT1|A0A087WWT1_HUMAN,tr|A0A087WXX8|A0A087WXX8_HUMAN" 3 1215.6356 1.14 7154 20602 2 1215.633686 608.8251 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.83 3796.1 - 953767 - - - -1.5342 - 2.521 0.607 - 389.2 1 2 0 -0.0019 11 0 0 0 5.75E+06 5.02E+06 - - - 6.0251 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.20603.20603.2 0.000206 18-Sep K.GPDWILGEIK[136.11].T "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 6 1134.6165 2.22 7155 20603 2 1134.621011 568.3155 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 4.37 3796.2 - 905835 - - - 4.011 - 1.934 0.416 - 225.4 1 2 0 0.0046 10 0 0 0 1.04E+07 4.70E+06 - - - 3.9533 1 230117_WJC_METTL3_WT_vs_EV_F01.20616.20616.2 0.00113 14/22 K.VESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1404.75 1.07 7165 20616 2 1404.748846 703.3823 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3797.6 - 2.23E+06 - - - -0.855 - 2.342 0.504 - 421.2 1 2 0 -0.0012 12 0 0 0 1.11E+07 1.03E+07 - - - 5.0023 0.998 230117_WJC_METTL3_WT_vs_EV_F01.20619.20619.2 0.00528 18-Oct K.VGDPVYLLGQ.- "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN" 2 1059.5601 - 7168 20619 2 1059.559155 530.7873 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 3.8 3798 - 1.84E+06 - - - -0.8551 - 1.698 0.284 - 284.6 1 2 0 -0.0009 10 0 0 0 - - - - - 2.6162 1 230117_WJC_METTL3_WT_vs_EV_F01.20621.20621.2 2.65E-09 15/30 K.IITLEEGDIILTGTPK.G sp|Q6P587|FAHD1_HUMAN 1 1711.9608 2.3 7170 20621 2 1711.957373 856.9877 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3798.2 - 984694 - - - -1.9831 - 3.248 0.623 - 614.9 1 2 0 -0.0034 16 0 0 0 9.70E+06 4.21E+06 - - - 6.5377 0.9942 230117_WJC_METTL3_WT_vs_EV_F01.20625.20625.2 0.00297 20-Oct K.VFLGNVETFIK.Q "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHA0|A0A6Q8PHA0_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF69|A0A6Q8PF69_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PGR0|A0A6Q8PGR0_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN,tr|A0A6Q8PFN8|A0A6Q8PFN8_HUMAN" 16 1265.702 1.29 7173 20625 2 1265.697897 633.8583 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 5.97 3798.7 - 403614 - - - -3.2211 - 1.688 0.364 - 277.8 1 2 0 -0.0041 11 0 0 0 4.36E+07 3.37E+07 - - - 3.1445 1 230117_WJC_METTL3_WT_vs_EV_F01.20629.20629.2 8.80E-06 24-Oct K.LFQEDDEIPLYLK[136.11].G "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6RGV5|D6RGV5_HUMAN" 4 1629.8381 1.84 7175 20629 2 1629.833987 815.9263 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 3.92 3799.3 - 499295 - - - -2.5481 - 2.154 0.515 - 264.7 1 2 0 -0.0042 13 0 0 0 1.95E+07 1.06E+07 - - - 4.8129 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.20630.20630.2 0.0314 14-Jul K.QELLELFK[136.11].E "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1026.5841 1.29 7176 20630 2 1026.584058 514.2993 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 4.53 3799.3 - 1.67E+06 - - - -0.039 - 1.496 0.264 - 168.4 1 2 0 0 8 0 0 0 1.69E+07 1.32E+07 - - - 2.2057 1 230117_WJC_METTL3_WT_vs_EV_F01.20631.20631.2 0.00136 20-Nov R.IISLETYNLLR.E "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1333.7606 2 7177 20631 2 1333.762085 667.8876 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 3799.4 - 1.03E+06 - - - 1.1494 - 2.332 0.451 - 352.4 1 2 0 0.0015 11 0 0 0 8.87E+06 4.43E+06 - - - 4.6622 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.20640.20640.3 0.00942 Aug-60 K.IITLEEGDIILTGTPK[136.11].G sp|Q6P587|FAHD1_HUMAN 1 1719.975 3.02 7186 20640 3 1719.975151 574.3323 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3800.6 - 0 - - - 0.1064 - 1.56 0.275 - 55.8 1 2 0 0.0002 16 0 0 0 2.75E+06 9.13E+05 - - - 2.7469 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.20642.20642.2 0.288 18-Oct K.INEWLTLVEK[136.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1251.6954 0.99 7187 20642 2 1251.692575 626.855 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.53 3800.9 - 554416 - - - -2.2881 - 2.265 0.289 - 429.8 1 2 0 -0.0029 10 0 0 0 1.75E+07 1.76E+07 - - - 3.4568 0.9837 230117_WJC_METTL3_WT_vs_EV_F01.20644.20644.2 0.381 14-Jul R.KIPVPANR[166.11].Y "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 903.553 - 7189 20644 2 903.552838 452.7838 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 11 3801.2 - 1.29E+06 - - - -0.1306 - 1.502 0.043 - 137.1 2 2 0 -0.0001 8 0 0 0 - - - - - 0.451 0.9896 230117_WJC_METTL3_WT_vs_EV_F01.20649.20649.2 0.0527 14-Jul R.EVMLILIR[166.11].E sp|O75533|SF3B1_HUMAN 1 995.6077 0.86 7194 20649 2 995.604939 498.8111 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.1 3801.8 - 368904 - - - -2.7672 - 1.594 0.231 - 196 1 2 0 -0.0028 8 0 0 0 6.72E+06 7.80E+06 - - - 2.1525 0.9973 230117_WJC_METTL3_WT_vs_EV_F01.20651.20651.2 0.193 14-Aug R.EVMLILIR.E sp|O75533|SF3B1_HUMAN 1 985.5994 0.85 7196 20651 2 985.598471 493.807 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.1 3802.1 - 320267 - - - -0.9669 - 1.692 0.234 - 278.8 1 2 0 -0.001 8 0 0 0 6.72E+06 7.92E+06 - - - 2.3551 1 230117_WJC_METTL3_WT_vs_EV_F01.20653.20653.2 2.28E-06 22-Nov R.LLTFMGMAVENK[136.11].E "sp|Q7L2H7|EIF3M_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 2 1360.6974 0.61 7197 20653 2 1360.694479 681.356 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6 3802.3 - 1.12E+06 - - - -2.1687 - 2.188 0.567 - 405.2 1 2 0 -0.003 12 0 0 0 8.67E+06 1.41E+07 - - - 5.2881 1 230117_WJC_METTL3_WT_vs_EV_F01.20655.20655.2 0.00143 13/22 K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.8 7198 20655 2 1317.703366 659.862 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3802.5 - 3.08E+06 - - - -4.5602 - 2.595 0.582 - 374.6 1 2 0 -0.006 12 0 0 0 2.50E+08 3.12E+08 - - - 5.8468 1 230117_WJC_METTL3_WT_vs_EV_F01.20657.20657.2 3.97E-06 14/24 K.LFQEDDEIPLYLK.G "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6RGV5|D6RGV5_HUMAN" 4 1621.8239 1.84 7200 20657 2 1621.829284 811.9192 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 3.92 3802.6 - 1.35E+06 - - - 3.2951 - 2.617 0.53 - 507.3 1 2 0 0.0053 13 0 0 0 1.95E+07 1.06E+07 - - - 5.423 1 230117_WJC_METTL3_WT_vs_EV_F01.20658.20658.2 7.52E-10 19/30 R.LMNDMTAVALNYGIYK.Q sp|Q92598|HS105_HUMAN 1 1815.8899 17.8 7201 20658 2 1815.894445 908.9522 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.83 3802.8 - 1.20E+06 - - - 2.4875 - 3.535 0.706 - 1318.1 1 2 0 0.0045 16 0 0 0 2.27E+07 1.27E+06 - - - 7.3585 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.20659.20659.2 0.00633 18-Sep K.AEVLWLMGAK[136.11].S sp|O94906|PRP6_HUMAN 1 1124.6144 0.96 7202 20659 2 1124.616347 563.3145 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.05 3802.9 - 623930 - - - 1.7739 - 1.616 0.316 - 308.1 1 2 0 0.002 10 0 0 0 1.93E+07 2.01E+07 - - - 2.714 1 230117_WJC_METTL3_WT_vs_EV_F01.20660.20660.2 5.29E-05 18-Oct -.MFLYNLTLQR.A "sp|Q15393|SF3B3_HUMAN,tr|H3BMB0|H3BMB0_HUMAN,tr|I3L4G7|I3L4G7_HUMAN" 3 1297.6853 0.23 7203 20660 2 1297.682443 649.8499 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.5 3803 - 582524 - - - -2.1847 - 2.237 0.5 - 374.7 1 2 0 -0.0028 10 0 0 0 3.05E+07 1.35E+08 - - - 4.9805 1 230117_WJC_METTL3_WT_vs_EV_F01.20661.20661.2 1.28E-07 16/34 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.9 7204 20661 2 1968.068435 985.0433 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3803.1 - 421938 - - - -1.8368 - 2.397 0.537 - 440.5 1 2 0 -0.0036 18 0 0 0 6.64E+06 3.49E+06 - - - 5.1555 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.20666.20666.2 0.000819 18-Sep K.AEVLWLMGAK.S sp|O94906|PRP6_HUMAN 1 1116.6002 0.95 7207 20666 2 1116.597488 559.3074 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.05 3803.7 - 1.52E+06 - - - -2.3858 - 1.771 0.498 - 318.3 1 2 0 -0.0027 10 0 0 0 1.91E+07 2.00E+07 - - - 4.3137 1 230117_WJC_METTL3_WT_vs_EV_F01.20667.20667.2 7.86E-07 13/22 R.VALDMTTLTIMR.Y "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 4 1363.7203 1.36 7208 20667 2 1363.717866 682.8674 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.81 3803.8 - 965448 - - - -1.8164 - 2.769 0.553 - 751 1 2 0 -0.0025 12 0 0 0 1.71E+07 1.26E+07 - - - 5.8045 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20668.20668.2 0.000324 20-Oct K.GVPTGFILPIR[166.11].D "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1178.7051 5.38 7209 20668 2 1178.707267 590.3598 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 3803.9 - 1.28E+06 - - - 1.8393 - 1.927 0.359 - 383.2 1 2 0 0.0022 11 0 0 0 2.72E+08 5.06E+07 - - - 3.4664 1 230117_WJC_METTL3_WT_vs_EV_F01.20669.20669.3 1.56E-08 17/44 K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.78 7210 20669 3 1317.707948 440.2437 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3804 - 905635 - - - -1.0829 - 2.682 0.617 - 523.4 1 2 0 -0.0014 12 0 0 0 1.36E+07 1.75E+07 - - - 8.1531 0.9946 230117_WJC_METTL3_WT_vs_EV_F01.20670.20670.2 0.0303 14-Jun R.EIFNFVLK[136.11].A sp|P78527|PRKDC_HUMAN 1 1016.5786 1.46 7211 20670 2 1016.576929 509.2966 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6.1 3804.1 - 787679 - - - -1.6615 - 1.283 0.315 - 123.7 1 2 0 -0.0017 8 0 0 0 2.16E+07 1.48E+07 - - - 2.1186 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.20671.20671.2 0.00221 12-Jul K.VFFDLMR[166.11].E "sp|P11234|RALB_HUMAN,sp|P11233|RALA_HUMAN" 2 936.4767 1.08 7212 20671 2 936.476332 469.2456 Ras-related protein Ral-B OS=Homo sapiens OX=9606 GN=RALB PE=1 SV=1 5.81 3804.2 - 719766 - - - -0.3705 - 1.42 0.36 - 216.3 1 2 0 -0.0003 7 0 0 0 1.13E+07 1.04E+07 - - - 2.8109 1 230117_WJC_METTL3_WT_vs_EV_F01.20672.20672.2 5.88E-08 15/28 K.GVYPDLLATSGDYLR[166.11].V sp|P61962|DCAF7_HUMAN 1 1648.8336 2.46 7213 20672 2 1648.830771 825.4241 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3804.3 - 592593 - - - -1.72 - 2.499 0.648 - 477.6 1 2 0 -0.0028 15 0 0 0 1.93E+07 7.84E+06 - - - 6.078 0.9142 230117_WJC_METTL3_WT_vs_EV_F01.20673.20673.2 0.0103 20-Oct K.FVPYLIAGIQH.S "sp|P12268|IMDH2_HUMAN,sp|P20839|IMDH1_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|C9J381|C9J381_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN,tr|A0A3B3IRL5|A0A3B3IRL5_HUMAN" 8 1256.6917 - 7214 20673 2 1256.69341 629.3531 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 6.74 3804.5 - 0 - - - 1.3257 - 1.549 0.269 - 309.4 1 1 0 0.0017 11 0 0 0 - - - - - 2.2111 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.20674.20674.2 0.000212 Nov-34 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.9 7215 20674 2 1976.084173 989.0504 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3804.6 - 0 - - - -1.0511 - 2.068 0.49 - 215.1 1 2 0 -0.0021 18 0 0 0 6.64E+06 3.49E+06 - - - 4.4458 1 230117_WJC_METTL3_WT_vs_EV_F01.20677.20677.2 0.000303 22-Dec K.TVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1309.6952 0.8 7216 20677 2 1309.69349 655.8549 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3805 - 6.60E+07 - - - -1.2866 - 2.566 0.531 - 299.9 1 2 0 -0.0017 12 0 0 0 2.50E+08 3.12E+08 - - - 5.4419 1 230117_WJC_METTL3_WT_vs_EV_F01.20678.20678.2 1.87E-08 14/22 K.GAVEALAAALAH.L sp|Q9NR30|DDX21_HUMAN 1 1092.5928 - 7217 20678 2 1092.590774 547.3037 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.24 3805 - 1.89E+07 - - - -1.8159 - 2.941 0.45 - 748.6 1 1 0 -0.002 12 0 0 0 - - - - - 5.2025 1 230117_WJC_METTL3_WT_vs_EV_F01.20679.20679.2 1.55E-06 16/28 K.GVYPDLLATSGDYLR.V sp|P61962|DCAF7_HUMAN 1 1638.8253 2.46 7218 20679 2 1638.817187 820.4199 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3805.2 - 4.56E+06 - - - -4.9731 - 2.738 0.624 - 573.1 1 2 0 -0.0081 15 0 0 0 1.93E+07 7.84E+06 - - - 6.1236 1 230117_WJC_METTL3_WT_vs_EV_F01.20680.20680.3 2.89E-07 19/44 K.TVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1309.6952 0.78 7219 20680 3 1309.689429 437.5723 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3805.3 - 3.67E+06 - - - -4.3873 - 3.213 0.56 - 673.2 1 2 0 -0.0057 12 0 0 0 1.36E+07 1.75E+07 - - - 8.0172 0.9845 230117_WJC_METTL3_WT_vs_EV_F01.20682.20682.2 0.00661 14-Sep R.LLDFLNVK[136.11].N sp|Q8NDZ4|DIK2A_HUMAN 1 968.5786 0.72 7221 20682 2 968.573874 485.2966 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 5.84 3805.5 - 3.23E+06 - - - -4.8979 - 1.53 0.394 - 190.5 1 2 0 -0.0047 8 0 0 0 7.76E+06 1.08E+07 - - - 3.2322 0.978 230117_WJC_METTL3_WT_vs_EV_F01.20685.20685.2 0.00636 14-Sep R.LLDFLNVK.N sp|Q8NDZ4|DIK2A_HUMAN 1 960.5644 0.72 7224 20685 2 960.559762 481.2895 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 5.84 3805.9 - 2.59E+06 - - - -4.8472 - 1.543 0.322 - 190.1 1 2 0 -0.0047 8 0 0 0 7.76E+06 1.08E+07 - - - 2.7259 1 230117_WJC_METTL3_WT_vs_EV_F01.20688.20688.2 2.84E-06 15/26 R.WSSMEIMEAYSVAR.Q "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|Q5TG81|Q5TG81_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 5 1658.7433 0.95 7227 20688 2 1658.730479 830.3789 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 4.53 3806.3 - 1.93E+06 - - - -7.7076 - 2.802 0.659 - 717.9 1 2 0 -0.0128 14 0 0 0 1.16E+07 1.22E+07 - - - 6.4899 0.9723 230117_WJC_METTL3_WT_vs_EV_F01.20689.20689.2 5.48E-05 18-Sep K.FTMVQVWPVR.Q "sp|P38606|VATA_HUMAN,tr|C9JA17|C9JA17_HUMAN,tr|C9JVW8|C9JVW8_HUMAN" 3 1261.6641 1.83 7228 20689 2 1261.656545 631.8394 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 9.75 3806.4 - 1.92E+06 - - - -6.027 - 1.974 0.332 - 329.9 1 2 0 -0.0076 10 0 0 0 8.64E+06 4.72E+06 - - - 3.389 1 230117_WJC_METTL3_WT_vs_EV_F01.20694.20694.2 4.00E-08 18/26 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.67 7233 20694 2 1487.770545 744.8959 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3807.1 - 1.26E+06 - - - -4.5168 - 2.834 0.499 - 962.3 1 2 0 -0.0067 14 0 0 0 3.25E+07 1.95E+07 - - - 5.3386 0.8767 230117_WJC_METTL3_WT_vs_EV_F01.20698.20698.2 0.0675 22-Aug R.LLTFMGMAVENK.E "sp|Q7L2H7|EIF3M_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 2 1352.6832 0.61 7236 20698 2 1352.675258 677.3489 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6 3807.6 - 0 - - - -5.8935 - 1.425 0.216 - 171.4 1 2 0 -0.008 12 0 0 0 8.67E+06 1.42E+07 - - - 1.5658 0.9684 230117_WJC_METTL3_WT_vs_EV_F01.20699.20699.2 0.0507 18-Aug K.YALVWGLSVK[136.11].H sp|Q9Y295|DRG1_HUMAN 1 1142.6579 -1 7237 20699 2 1142.653792 572.3362 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 8.59 3807.6 - 310850 - - - -3.6223 - 1.615 0.184 - 114 2 2 0 -0.0041 10 0 0 0 0.00E+00 0.00E+00 - - - 1.6022 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20703.20703.2 0.000224 16-Jul K.LLYTFPGWK[136.11].V "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1131.6208 1.8 7241 20703 2 1131.621597 566.8177 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 8.59 3807.8 - 1.47E+06 - - - 0.6893 - 1.617 0.535 - 147.6 1 2 0 0.0008 9 0 0 0 1.87E+07 1.04E+07 - - - 4.3826 1 230117_WJC_METTL3_WT_vs_EV_F01.20705.20705.2 0.000164 18-Oct K.VLEAELLVLR[166.11].Q sp|P07196|NFL_HUMAN 1 1163.7153 0.69 7243 20705 2 1163.713321 582.8649 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.53 3807.9 - 1.40E+06 - - - -1.7264 - 2.009 0.522 - 335.8 1 2 0 -0.002 10 0 0 0 6.28E+06 9.06E+06 - - - 4.8432 1 230117_WJC_METTL3_WT_vs_EV_F01.20707.20707.2 1.14E-05 13/22 K.FLETVELQISLK[136.11].N sp|P62906|RL10A_HUMAN 1 1426.8163 0.99 7245 20707 2 1426.816012 714.4154 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.53 3808.1 - 1.14E+06 - - - -0.1892 - 2.581 0.567 - 469.5 1 2 0 -0.0003 12 0 0 0 8.44E+06 8.53E+06 - - - 5.7236 0.9782 230117_WJC_METTL3_WT_vs_EV_F01.20710.20710.2 0.156 20-Aug K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 999 7248 20710 2 1184.71761 593.3637 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3808.5 - 0 - - - 3.9984 - 1.309 0.14 - 108.8 1 2 0 0.0047 11 0 0 0 2.35E+06 0.00E+00 - - - 0.802 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.20716.20716.3 0.000121 13/52 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.66 7252 20716 3 1487.77424 496.933 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3809.2 - 374676 - - - -2.0332 - 1.745 0.442 - 150.1 1 2 0 -0.003 14 0 0 0 5.65E+06 3.40E+06 - - - 4.9466 0.8721 230117_WJC_METTL3_WT_vs_EV_F01.20720.20720.2 0.00926 18-Jul R.LGFEGGQTPF.Y "sp|Q9P015|RM15_HUMAN,tr|E5RHF4|E5RHF4_HUMAN" 2 1051.4975 - 7256 20720 2 1051.497089 526.756 "39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1" 4 3809.5 - 739697 - - - -0.3538 - 1.282 0.356 - 110.4 1 1 0 -0.0004 10 0 0 0 - - - - - 2.3637 0.9962 230117_WJC_METTL3_WT_vs_EV_F01.20724.20724.2 0.000243 16-Aug R.YEGFFGLYR[166.11].G "sp|O75746|CMC1_HUMAN,sp|Q9UJS0|CMC2_HUMAN" 2 1160.553 0.83 7260 20724 2 1160.554269 581.2838 Calcium-binding mitochondrial carrier protein Aralar1 OS=Homo sapiens OX=9606 GN=SLC25A12 PE=1 SV=2 6 3809.8 - 283554 - - - 1.0805 - 1.591 0.11 - 196.1 1 2 0 0.0013 9 0 0 0 2.88E+06 3.48E+06 - - - 1.1965 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20725.20725.2 3.08E-05 16-Aug K.LLYTFPGWK.V "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1123.6066 1.8 7261 20725 2 1123.607333 562.8106 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 8.59 3809.8 - 247366 - - - 0.6372 - 1.747 0.509 - 166.1 1 2 0 0.0007 9 0 0 0 1.87E+07 1.04E+07 - - - 4.4143 0.9771 230117_WJC_METTL3_WT_vs_EV_F01.20728.20728.2 0.00122 22-Oct K.FLETVELQISLK.N sp|P62906|RL10A_HUMAN 1 1418.8021 0.99 7264 20728 2 1418.794357 710.4083 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.53 3810.1 - 102013 - - - -5.4447 - 1.669 0.374 - 167.3 1 2 0 -0.0077 12 0 0 0 8.44E+06 8.53E+06 - - - 3.1487 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.20738.20738.2 6.75E-05 20-Dec K.GIFNGFSVTLK.E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1181.6445 1.16 7272 20738 2 1181.640777 591.8295 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3811.4 - 4.48E+06 - - - -3.116 - 2.311 0.416 - 353 1 2 0 -0.0037 11 0 0 0 1.09E+07 9.38E+06 - - - 4.3785 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.20739.20739.2 6.00E-07 20-Nov K.GIFNGFSVTLK[136.11].E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1189.6587 1.16 7273 20739 2 1189.656898 595.8366 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3811.5 - 4.24E+06 - - - -1.4803 - 2.152 0.382 - 255 1 2 0 -0.0018 11 0 0 0 1.09E+07 9.38E+06 - - - 3.9352 1 230117_WJC_METTL3_WT_vs_EV_F01.20740.20740.2 1.23E-08 16/24 R.GAVGALLVYDIAK.H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1288.7391 1.58 7274 20740 2 1288.735133 645.3768 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3811.6 - 2.43E+06 - - - -3.0689 - 3.293 0.444 - 1540.1 1 2 0 -0.004 13 0 0 0 4.24E+07 2.69E+07 - - - 5.3779 0.9969 230117_WJC_METTL3_WT_vs_EV_F01.20741.20741.2 0.00234 12-Aug R.WQFLTLR.E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 962.5338 1.61 7275 20741 2 962.531372 482.2742 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 9.75 3811.8 - 1.92E+06 - - - -2.509 - 1.663 0.377 - 295.5 1 2 0 -0.0024 7 0 0 0 6.01E+06 3.74E+06 - - - 3.4364 0.9928 230117_WJC_METTL3_WT_vs_EV_F01.20742.20742.2 0.0172 14-Aug K.DTLGLFLR[166.11].E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 943.5366 1.51 7276 20742 2 943.53461 472.7756 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.84 3811.9 - 1.91E+06 - - - -2.1483 - 1.58 0.232 - 231.3 1 2 0 -0.002 8 0 0 0 5.79E+07 3.83E+07 - - - 2.1335 0.9936 230117_WJC_METTL3_WT_vs_EV_F01.20743.20743.2 0.0457 14-Aug R.VLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 881.6062 1.33 7277 20743 2 881.603227 441.8104 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3812 - 1.73E+06 - - - -3.3983 - 1.701 0.341 - 165.6 1 2 0 -0.003 8 0 0 0 2.95E+07 2.22E+07 - - - 3.1608 1 230117_WJC_METTL3_WT_vs_EV_F01.20744.20744.2 3.45E-07 13/20 K.FMELLEPLNER.K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1389.6962 -1 7278 20744 2 1389.691757 695.8554 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.25 3812.1 - 1.71E+06 - - - -3.2237 - 2.509 0.545 - 790.7 1 2 0 -0.0045 11 0 0 0 0.00E+00 0.00E+00 - - - 5.5535 0.9926 230117_WJC_METTL3_WT_vs_EV_F01.20745.20745.2 0.192 14-Sep R.VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 891.6145 1.33 7279 20745 2 891.611574 446.8145 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3812.3 - 1.51E+06 - - - -3.2738 - 1.908 0.255 - 358.2 1 2 0 -0.0029 8 0 0 0 2.95E+07 2.22E+07 - - - 2.872 0.9685 230117_WJC_METTL3_WT_vs_EV_F01.20746.20746.2 0.00057 12-Aug R.WQFLTLR[166.11].E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 972.5421 1.61 7280 20746 2 972.536489 487.2783 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 9.75 3812.4 - 1.27E+06 - - - -5.7252 - 1.652 0.314 - 296.8 1 2 0 -0.0056 7 0 0 0 6.01E+06 3.74E+06 - - - 2.949 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20747.20747.2 9.04E-06 13/28 K.FGANAILGVSLAVC[160.03]K.A "sp|P13929|ENOB_HUMAN,sp|P06733|ENOA_HUMAN,sp|P09104|ENOG_HUMAN,tr|E5RI09|E5RI09_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|E5RG95|E5RG95_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN,tr|K7EPM1|K7EPM1_HUMAN,tr|K7EKN2|K7EKN2_HUMAN" 12 1518.8228 3.07 7281 20747 2 1518.822247 760.4187 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 8.22 3812.5 - 1.13E+06 - - - -0.3871 - 2.042 0.51 - 391.6 1 2 0 -0.0006 15 0 0 0 3.15E+06 1.03E+06 - - - 4.5629 1 230117_WJC_METTL3_WT_vs_EV_F01.20748.20748.2 8.36E-05 14/20 R.LLGAALPLLTK[136.11].E "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1116.7362 0.8 7282 20748 2 1116.732925 559.3754 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 8.75 3812.7 - 1.03E+06 - - - -2.9165 - 2.608 0.449 - 416.8 1 2 0 -0.0033 11 0 0 0 1.70E+06 2.11E+06 - - - 4.9495 1 230117_WJC_METTL3_WT_vs_EV_F01.20749.20749.2 1.89E-09 17/28 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.28 7283 20749 2 1548.924969 775.4692 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3812.8 - 1.03E+06 - - - 0.6714 - 3.64 0.637 - 667.5 1 2 0 0.001 15 0 0 0 7.44E+07 5.83E+07 - - - 6.922 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.20751.20751.2 0.000192 16-Sep R.LVSYYYFLR[166.11].F sp|Q7LGA3|HS2ST_HUMAN 1 1232.6469 0.99 7285 20751 2 1232.644013 617.3307 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 8.5 3813.1 - 945649 - - - -2.3551 - 1.751 0.403 - 293.5 1 2 0 -0.0029 9 0 0 0 9.18E+06 9.27E+06 - - - 3.6373 1 230117_WJC_METTL3_WT_vs_EV_F01.20759.20759.2 2.47E-05 16-Oct K.C[160.03]MPTFQFFK.K sp|P10599|THIO_HUMAN 1 1204.5409 2.67 7292 20759 2 1204.541077 603.2777 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3814 - 2.56E+06 - - - 0.1278 - 1.726 0.574 - 240.6 1 2 0 0.0002 9 0 0 0 3.66E+07 1.37E+07 - - - 4.8596 1 230117_WJC_METTL3_WT_vs_EV_F01.20760.20760.2 0.000124 13/24 R.GAVGALLVYDIAK[136.11].H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1296.7533 1.58 7293 20760 2 1296.754084 649.3839 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3814.1 - 2.42E+06 - - - 0.6138 - 3.045 0.503 - 920.9 1 2 0 0.0008 13 0 0 0 4.24E+07 2.69E+07 - - - 5.6137 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20761.20761.2 0.00165 16-Sep R.LVSYYYFLR.F sp|Q7LGA3|HS2ST_HUMAN 1 1222.6386 0.99 7294 20761 2 1222.640521 612.3266 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 8.5 3814.2 - 1.68E+06 - - - 1.5336 - 1.666 0.446 - 314.3 1 2 0 0.0019 9 0 0 0 9.18E+06 9.27E+06 - - - 3.8113 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.20762.20762.2 0.00784 16-Jul K.C[160.03]MPTFQFFK[136.11].K sp|P10599|THIO_HUMAN 1 1212.5551 2.67 7295 20762 2 1212.555001 607.2848 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3814.3 - 1.18E+06 - - - -0.1006 - 1.147 0.443 - 99.2 1 2 0 -0.0001 9 0 0 0 3.66E+07 1.37E+07 - - - 2.7097 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.20764.20764.3 6.40E-06 19/60 R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 12.12 7297 20764 3 1756.909479 586.6429 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3814.6 - 765500 - - - 1.4349 - 2.606 0.435 - 456.1 1 2 0 0.0025 16 0 0 0 3.43E+07 2.83E+06 - - - 5.8467 1 230117_WJC_METTL3_WT_vs_EV_F01.20766.20766.2 4.68E-06 15/24 K.ILESSQTLLSVLK.R "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1429.8392 4.19 7299 20766 2 1429.838506 715.9269 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 6 3814.9 - 701288 - - - -0.4826 - 2.899 0.567 - 551.5 1 2 0 -0.0007 13 0 0 0 1.36E+07 3.25E+06 - - - 5.9604 1 230117_WJC_METTL3_WT_vs_EV_F01.20768.20768.2 1.77E-07 18/28 K.LLGASELPIVTPALR[166.11].A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1558.9322 1.27 7301 20768 2 1558.933042 780.4734 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3815.1 - 638581 - - - 0.5408 - 3.469 0.571 - 682.4 1 2 0 0.0008 15 0 0 0 7.91E+07 6.21E+07 - - - 6.3162 1 230117_WJC_METTL3_WT_vs_EV_F01.20769.20769.2 0.00294 18-Nov K.MAEMLVELVR[166.11].R sp|Q9Y605|MOFA1_HUMAN 1 1199.6282 2.5 7302 20769 2 1199.628156 600.8214 MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1 4.53 3815.2 - 611165 - - - -0.0125 - 2.307 0.445 - 605.7 1 2 0 0 10 0 0 0 1.44E+07 5.76E+06 - - - 4.6612 1 230117_WJC_METTL3_WT_vs_EV_F01.20770.20770.2 5.27E-15 18/30 R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 15.3 7303 20770 2 1756.908719 879.4608 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3815.4 - 610823 - - - 1.0023 - 3.714 0.586 - 1189.6 1 2 0 0.0018 16 0 0 0 5.95E+07 3.89E+06 - - - 6.5945 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.20771.20771.2 0.0066 18-Oct R.IYLDMLNVYK.C "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 11 1270.6631 1.65 7304 20771 2 1270.663248 636.3388 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.83 3815.5 - 549765 - - - 0.0803 - 1.845 0.226 - 243.4 1 2 0 0.0001 10 0 0 0 1.57E+07 9.52E+06 - - - 2.4198 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.20772.20772.2 0.0231 18-Oct K.DLIGVQNLLK[136.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1119.6743 1 7305 20772 2 1119.673879 560.8444 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3815.6 - 549010 - - - -0.3849 - 2.081 0.357 - 284 1 2 0 -0.0004 10 0 0 0 1.54E+07 1.53E+07 - - - 3.7233 0.994 230117_WJC_METTL3_WT_vs_EV_F01.20776.20776.2 0.0482 20-Jul K.FMELLEPLNER[166.11].K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1399.7045 1.09 7309 20776 2 1399.701754 700.8595 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.25 3816.2 - 223244 - - - -1.9668 - 1.49 0.281 - 146.6 1 2 0 -0.0028 11 0 0 0 2.87E+06 2.63E+06 - - - 2.1944 0.9976 230117_WJC_METTL3_WT_vs_EV_F01.20778.20778.2 0.0451 14-Aug K.AWGILTFK.G "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 934.5276 1.35 7310 20778 2 934.528577 468.2711 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 8.8 3816.4 - 7.86E+06 - - - 1.0037 - 1.443 0.196 - 279.7 1 2 0 0.0009 8 0 0 0 7.11E+07 5.27E+07 - - - 1.5944 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20781.20781.2 0.000466 22-Aug K.IGLIQFC[160.03]LSAPK.T sp|P50991|TCPD_HUMAN 1 1345.7428 9.07 7313 20781 2 1345.745058 673.8787 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3816.6 - 1.70E+06 - - - 1.6823 - 1.906 0.426 - 248.6 1 2 0 0.0023 12 0 0 0 1.20E+08 1.33E+07 - - - 3.8838 1 230117_WJC_METTL3_WT_vs_EV_F01.20783.20783.2 4.65E-06 20-Nov K.YFFFDDGNGLK.G sp|P61009|SPCS3_HUMAN 1 1321.5979 1.3 7315 20783 2 1321.597147 661.8062 Signal peptidase complex subunit 3 OS=Homo sapiens OX=9606 GN=SPCS3 PE=1 SV=1 4.21 3816.8 - 373140 - - - -0.572 - 1.882 0.586 - 334 1 2 0 -0.0008 11 0 0 0 4.96E+06 3.80E+06 - - - 5.0796 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20785.20785.2 0.000274 22-Oct R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 -1 7316 20785 2 1603.764656 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3817.1 - 1.98E+08 - - - 0.4464 - 1.957 0.507 - 278.3 1 2 0 0.0007 12 0 0 0 0.00E+00 0.00E+00 - - - 4.5521 1 230117_WJC_METTL3_WT_vs_EV_F01.20788.20788.2 0.00102 15/30 R.LMNETTAVALAYGIYK[136.11].Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1764.9212 15.17 7318 20788 2 1764.916535 883.4679 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3817.4 - 1.10E+06 - - - -2.6194 - 3.132 0.581 - 493.1 1 2 0 -0.0046 16 0 0 0 5.90E+07 3.89E+06 - - - 6.1377 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.20789.20789.2 1.49E-05 16-Sep R.FTGLESIFR[166.11].A sp|Q8N4Q0|PTGR3_HUMAN 1 1078.5687 0.71 7319 20789 2 1078.567588 540.2916 Prostaglandin reductase 3 OS=Homo sapiens OX=9606 GN=ZADH2 PE=1 SV=1 6 3817.4 - 1.24E+07 - - - -0.9985 - 1.761 0.522 - 276.4 1 2 0 -0.0011 9 0 0 0 3.00E+07 4.23E+07 - - - 4.5333 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.20791.20791.2 0.00749 18-Sep K.DLIGVQNLLK.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1111.6601 1 7321 20791 2 1111.659461 556.8373 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3817.5 - 9.39E+06 - - - -0.5838 - 2.034 0.328 - 220.4 1 2 0 -0.0006 10 0 0 0 1.54E+07 1.53E+07 - - - 3.4452 1 230117_WJC_METTL3_WT_vs_EV_F01.20792.20792.3 2.02E-05 15/56 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.17 7322 20792 3 1548.925079 517.3153 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3817.6 - 6.76E+06 - - - 0.7425 - 2.935 0.499 - 346.5 1 2 0 0.0011 15 0 0 0 9.54E+06 8.14E+06 - - - 6.9126 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.20793.20793.3 0.000318 Nov-56 K.LLGASELPIVTPALR[166.11].A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1558.9322 1.18 7323 20793 3 1558.931771 520.6513 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3817.6 - 5.52E+06 - - - -0.2745 - 2.161 0.509 - 197.6 1 2 0 -0.0004 15 0 0 0 9.90E+06 8.36E+06 - - - 6.2254 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.20794.20794.2 0.0152 18-Oct R.IYLDMLNVYK[136.11].C "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 11 1278.6773 2.43 7324 20794 2 1278.676558 640.3459 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.83 3817.7 - 5.36E+06 - - - -0.6163 - 1.908 0.43 - 326.5 1 2 0 -0.0008 10 0 0 0 2.36E+07 9.70E+06 - - - 4.0201 1 230117_WJC_METTL3_WT_vs_EV_F01.20796.20796.2 6.93E-06 22-Dec K.IGLIQFC[160.03]LSAPK[136.11].T sp|P50991|TCPD_HUMAN 1 1353.757 9.03 7326 20796 2 1353.757887 677.8858 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3817.8 - 3.58E+06 - - - 0.6596 - 2.497 0.48 - 573.6 1 2 0 0.0009 12 0 0 0 1.20E+08 1.33E+07 - - - 4.9938 0.9912 230117_WJC_METTL3_WT_vs_EV_F01.20797.20797.2 0.0428 16-Oct R.NALDLLLPK[136.11].L "sp|P30566|PUR8_HUMAN,tr|A0A096LNY5|A0A096LNY5_HUMAN,tr|A0A1B0GTJ7|A0A1B0GTJ7_HUMAN,tr|A0A1B0GWJ0|A0A1B0GWJ0_HUMAN,tr|A0A1B0GWF8|A0A1B0GWF8_HUMAN,tr|A0A096LNY4|A0A096LNY4_HUMAN,tr|A0A1B0GTG9|A0A1B0GTG9_HUMAN,tr|A0A7P0T9A7|A0A7P0T9A7_HUMAN,tr|A0A096LNY6|A0A096LNY6_HUMAN,tr|A0A096LP92|A0A096LP92_HUMAN,tr|A0A7P0Z472|A0A7P0Z472_HUMAN" 11 1003.6157 2.49 7327 20797 2 1003.614375 502.8151 Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2 5.84 3817.8 - 1.92E+06 - - - -1.3521 - 1.499 0.173 - 222 1 2 0 -0.0014 9 0 0 0 1.04E+07 4.16E+06 - - - 1.4895 0.9973 230117_WJC_METTL3_WT_vs_EV_F01.20800.20800.2 1.82 18-Sep K.QLLLIAGLTR.E "sp|Q9UJX2|CDC23_HUMAN,tr|D6RCF8|D6RCF8_HUMAN,tr|D6RBY8|D6RBY8_HUMAN,tr|H0Y936|H0Y936_HUMAN" 4 1096.6968 1.03 7330 20800 2 1096.69544 549.3557 Cell division cycle protein 23 homolog OS=Homo sapiens OX=9606 GN=CDC23 PE=1 SV=3 9.75 3818 - 1.70E+06 - - - -1.2665 - 2.021 0.214 - 216.5 1 2 0 -0.0014 10 0 0 0 5.41E+06 5.25E+06 - - - 2.5851 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.20801.20801.3 0.019 Oct-48 R.GAVGALLVYDIAK.H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1288.7391 1.64 7331 20801 3 1288.738784 430.587 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3818.1 - 1.70E+06 - - - -0.2359 - 1.651 0.29 - 114.1 1 2 0 -0.0003 13 0 0 0 2.99E+06 1.83E+06 - - - 3.1325 0.9752 230117_WJC_METTL3_WT_vs_EV_F01.20802.20802.2 1.02 12-Jun K.DLVEWLK[136.11].L "sp|Q9P2D1|CHD7_HUMAN,sp|Q14554|PDIA5_HUMAN" 2 909.5051 2.15 7332 20802 2 909.504805 455.7598 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.37 3818.2 - 1.15E+06 - - - -0.3452 - 1.045 0.144 - 139 1 2 0 -0.0003 7 0 0 0 5.52E+06 2.57E+06 - - - 0.244 0.9803 230117_WJC_METTL3_WT_vs_EV_F01.20803.20803.2 2.89 12-Jun R.DLLDVLK[136.11].S "sp|Q9Y6R4|M3K4_HUMAN,tr|J3KNB8|J3KNB8_HUMAN,tr|F5H538|F5H538_HUMAN,tr|F5H4R1|F5H4R1_HUMAN" 4 822.4942 0.77 7333 20803 2 822.494208 412.2544 Mitogen-activated protein kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP3K4 PE=1 SV=2 4.21 3818.4 - 974626 - - - -0.0146 - 1.254 0.07 - 127.5 1 2 0 0 7 0 0 0 1.66E+06 2.14E+06 - - - 0.2752 1 230117_WJC_METTL3_WT_vs_EV_F01.20805.20805.2 1.37E-05 20-Nov R.LHQLLALTLWK.E "sp|Q7L5D6|GET4_HUMAN,tr|C9JPA8|C9JPA8_HUMAN,tr|C9JHN8|C9JHN8_HUMAN,tr|C9JY46|C9JY46_HUMAN" 4 1334.8074 -1 7335 20805 2 1334.812197 668.411 Golgi to ER traffic protein 4 homolog OS=Homo sapiens OX=9606 GN=GET4 PE=1 SV=1 8.76 3818.6 - 941004 - - - 3.5616 - 2.363 0.514 - 415.4 1 2 0 0.0048 11 0 0 0 0.00E+00 0.00E+00 - - - 5.1622 0.9879 230117_WJC_METTL3_WT_vs_EV_F01.20806.20806.2 0.85 18-Aug R.EYLLDMIPPR.S "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 3 1245.6427 -1 7336 20806 2 1245.642795 623.8286 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.37 3818.6 - 621759 - - - 0.0401 - 0.982 0.217 - 137.4 1 2 0 0.0001 10 0 0 0 0.00E+00 0.00E+00 - - - 0.593 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.20808.20808.3 1.82E-05 Sep-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 7337 20808 3 1603.763425 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3818.9 - 4.10E+07 - - - -0.3211 - 1.775 0.515 - 143.7 1 2 0 -0.0005 12 0 0 0 4.43E+08 0.00E+00 - - - 5.8721 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.20810.20810.2 6.00E-05 18-Nov K.IMLPWDPTGK[136.11].L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1164.6093 1.86 7339 20810 2 1164.608474 583.3119 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3819.1 - 4.01E+06 - - - -0.6801 - 1.881 0.47 - 449.2 1 2 0 -0.0008 10 0 0 0 7.03E+07 3.77E+07 - - - 4.2757 0.9917 230117_WJC_METTL3_WT_vs_EV_F01.20811.20811.2 0.00181 16-Sep R.FVC[160.03]PVILFK[136.11].G "sp|Q8NCE2|MTMRE_HUMAN,tr|B4DJ23|B4DJ23_HUMAN" 2 1129.6449 0.73 7340 20811 2 1129.641915 565.8297 Myotubularin-related protein 14 OS=Homo sapiens OX=9606 GN=MTMR14 PE=1 SV=2 8.22 3819.2 - 3.13E+06 - - - -2.6637 - 1.635 0.251 - 243.1 1 2 0 -0.003 9 0 0 0 5.82E+06 7.99E+06 - - - 2.3163 1 230117_WJC_METTL3_WT_vs_EV_F01.20812.20812.2 4.13E-08 14/20 K.WYLENVYPELR.V sp|Q10471|GALT2_HUMAN 1 1480.7351 0.94 7341 20812 2 1480.733944 741.3748 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3819.3 - 2.03E+06 - - - -0.7571 - 2.501 0.495 - 776 1 2 0 -0.0011 11 0 0 0 3.99E+07 4.26E+07 - - - 5.1766 1 230117_WJC_METTL3_WT_vs_EV_F01.20813.20813.2 1.16E-05 18-Oct R.AFDLFNPNFK[136.11].S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1219.6117 1.63 7342 20813 2 1219.610904 610.8131 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3819.4 - 2.02E+06 - - - -0.66 - 1.959 0.514 - 278.3 1 2 0 -0.0008 10 0 0 0 2.72E+07 1.67E+07 - - - 4.7141 1 230117_WJC_METTL3_WT_vs_EV_F01.20816.20816.2 7.44E-05 14/22 R.VPFLVLEC[160.03]PNLK[136.11].L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1435.7989 1.15 7345 20816 2 1435.799221 718.9067 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3819.8 - 1.70E+06 - - - 0.2528 - 2.595 0.516 - 822.9 1 2 0 0.0004 12 0 0 0 1.76E+07 1.53E+07 - - - 5.3611 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.20817.20817.2 0.0528 18-Nov K.ILDVLEEIPK[136.11].N "sp|Q16718|NDUA5_HUMAN,tr|C9IZN5|C9IZN5_HUMAN,tr|H7BYD0|H7BYD0_HUMAN,tr|A0A087X1G1|A0A087X1G1_HUMAN,tr|F8WAS3|F8WAS3_HUMAN,tr|A0A7I2V2W4|A0A7I2V2W4_HUMAN,tr|A0A7I2V3L8|A0A7I2V3L8_HUMAN" 7 1175.6893 2.29 7346 20817 2 1175.687406 588.8519 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3 4.14 3819.9 - 1.59E+06 - - - -1.6033 - 2.143 0.301 - 194 1 2 0 -0.0019 10 0 0 0 8.00E+07 3.50E+07 - - - 3.3911 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20830.20830.2 8.36E-06 18-Jul R.AFDLFNPNFK.S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1211.5975 1.64 7357 20830 2 1211.597748 606.806 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3821.6 - 1.57E+06 - - - 0.1973 - 1.712 0.447 - 132.8 1 2 0 0.0002 10 0 0 0 2.74E+07 1.67E+07 - - - 3.8432 0.9951 230117_WJC_METTL3_WT_vs_EV_F01.20831.20831.2 0.028 12-Jul R.EIALWFR.A "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 933.5072 1.26 7358 20831 2 933.505755 467.7609 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6.1 3821.6 - 1.57E+06 - - - -1.5886 - 1.398 0.28 - 253.9 1 2 0 -0.0015 7 0 0 0 1.82E+07 1.44E+07 - - - 2.1702 0.9959 230117_WJC_METTL3_WT_vs_EV_F01.20832.20832.2 0.258 12-Jul R.EIALWFR[166.11].A "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 943.5155 1.26 7359 20832 2 943.513833 472.765 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6.1 3821.7 - 1.56E+06 - - - -1.7753 - 1.633 0.253 - 275.7 1 2 0 -0.0017 7 0 0 0 1.80E+07 1.44E+07 - - - 2.4631 1 230117_WJC_METTL3_WT_vs_EV_F01.20836.20836.2 0.000698 17/22 R.VPFLVLEC[160.03]PNLK.L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1427.7847 1.15 7363 20836 2 1427.785864 714.8996 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3822.1 - 686683 - - - 0.8447 - 2.865 0.529 - 1388.9 1 2 0 0.0012 12 0 0 0 1.76E+07 1.53E+07 - - - 5.7173 0.9597 230117_WJC_METTL3_WT_vs_EV_F01.20837.20837.2 1.89 14-Jun K.LFGLPNDS.- "sp|Q96J01|THOC3_HUMAN,tr|D6REC9|D6REC9_HUMAN" 2 861.4232 - 7364 20837 2 861.42328 431.7189 THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1 3.8 3822.1 - 665306 - - - 0.0546 - 0.956 0.117 - 83.9 1 2 0 0 8 0 0 0 - - - - - -0.2306 0.9657 230117_WJC_METTL3_WT_vs_EV_F01.20838.20838.2 0.000129 18-Nov L.C[160.03]FVYPLDFAR.T "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 4 1286.6118 1.06 7365 20838 2 1286.611643 644.3132 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 5.83 3822.3 - 588967 - - - -0.1057 - 2.003 0.441 - 466.5 1 1 0 -0.0001 10 0 0 0 5.72E+06 5.39E+06 - - - 4.2372 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.20844.20844.2 0.00793 18-Oct K.IMLPWDPTGK.L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1156.5951 1.86 7369 20844 2 1156.593523 579.3048 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3823 - 8.31E+06 - - - -1.3341 - 1.854 0.478 - 390.9 1 2 0 -0.0015 10 0 0 0 7.03E+07 3.78E+07 - - - 4.2942 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20846.20846.2 5.71E-05 13/20 K.IFGVTTLDIVR.A "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1232.7129 1.2 7371 20846 2 1232.714607 617.3637 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 5.84 3823.2 - 3.71E+06 - - - 1.4067 - 2.335 0.385 - 669.3 1 2 0 0.0017 11 0 0 0 4.43E+07 3.68E+07 - - - 4.1781 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20847.20847.2 0.00416 20-Nov K.FLFVDADQIVR.T sp|Q9NYU2|UGGG1_HUMAN 1 1321.703 9 7372 20847 2 1321.702985 661.8588 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.21 3823.3 - 2.08E+06 - - - -0.0393 - 2.077 0.404 - 363.1 1 2 0 -0.0001 11 0 0 0 5.70E+07 6.34E+06 - - - 4.0023 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20848.20848.2 0.00717 18-Oct K.VVILNVDLLK.L "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1124.7169 1.26 7373 20848 2 1124.717981 563.3657 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 5.81 3823.4 - 2.07E+06 - - - 0.9647 - 1.793 0.349 - 364.5 1 2 0 0.0011 10 0 0 0 7.22E+06 5.73E+06 - - - 3.2482 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.20849.20849.2 3.13E-05 22-Aug K.LVGQSIIAYLQK.K "sp|P53621|COPA_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 3 1331.7813 0.72 7374 20849 2 1331.780085 666.8979 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 8.59 3823.5 - 1.97E+06 - - - -0.9026 - 2.027 0.474 - 139.5 1 2 0 -0.0012 12 0 0 0 6.99E+06 9.67E+06 - - - 4.4007 1 230117_WJC_METTL3_WT_vs_EV_F01.20850.20850.2 0.00106 16-Sep R.FYNLVLLPR.V "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1133.6597 1.2 7375 20850 2 1133.65874 567.8371 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 3823.6 - 1.89E+06 - - - -0.8609 - 1.832 0.524 - 327.9 1 2 0 -0.001 9 0 0 0 4.44E+07 3.69E+07 - - - 4.6624 0.9956 230117_WJC_METTL3_WT_vs_EV_F01.20854.20854.2 0.00501 16-Sep K.TEILPPFFK.H sp|O75533|SF3B1_HUMAN 1 1090.6063 0.99 7379 20854 2 1090.603441 546.3104 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.66 3824 - 1.09E+06 - - - -2.6059 - 1.622 0.346 - 318.3 1 2 0 -0.0028 9 0 0 0 6.27E+07 6.34E+07 - - - 2.9949 0.9852 230117_WJC_METTL3_WT_vs_EV_F01.20855.20855.2 1.33E-05 18-Oct K.FSDFLLDPYK[136.11].Y sp|Q9UIG0|BAZ1B_HUMAN 1 1251.6267 1 7380 20855 2 1251.637834 626.8206 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 4.21 3824.1 - 765262 - - - 8.9028 - 1.863 0.483 - 251.6 1 2 0 0.0111 10 0 0 0 1.21E+07 1.21E+07 - - - 4.3417 1 230117_WJC_METTL3_WT_vs_EV_F01.20858.20858.2 4.51E-09 15/30 K.LPPPLSAPVAGLAALK.A sp|Q14781|CBX2_HUMAN 1 1513.9232 1.83 7383 20858 2 1513.92469 757.9689 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.75 3824.5 - 372318 - - - 0.9835 - 2.451 0.596 - 543.4 1 2 0 0.0015 16 0 0 0 3.22E+06 1.77E+06 - - - 5.6467 0.984 230117_WJC_METTL3_WT_vs_EV_F01.20864.20864.2 0.0936 16-Jul K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 5193.2 7387 20864 2 1014.537901 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3825.2 - 3.06E+07 - - - 3.2784 - 1.5 0.082 - 98.1 2 2 0 0.0033 9 0 0 0 2.98E+08 5.75E+04 - - - 0.6842 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.20865.20865.3 3.18E-06 Oct-56 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 592.33 7388 20865 3 1658.909884 553.977 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3825.2 - 1.54E+07 - - - 0.4925 - 2.272 0.476 - 143.8 1 2 0 0.0008 15 0 0 0 1.94E+08 3.27E+05 - - - 5.9881 1 230117_WJC_METTL3_WT_vs_EV_F01.20866.20866.2 3.41E-07 15/28 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 311.87 7389 20866 2 1658.903907 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3825.2 - 2.23E+07 - - - -3.1105 - 2.973 0.561 - 793.2 1 2 0 -0.0052 15 0 0 0 2.27E+08 7.28E+05 - - - 5.8617 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20867.20867.2 0.0566 20-Sep K.IFGVTTLDIVR[166.11].A "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1242.7211 1.19 7390 20867 2 1242.721343 622.3678 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 5.84 3825.3 - 1.25E+07 - - - 0.1609 - 1.856 0.418 - 249.3 1 2 0 0.0002 11 0 0 0 4.43E+07 3.71E+07 - - - 3.8013 1 230117_WJC_METTL3_WT_vs_EV_F01.20869.20869.2 4.78E-06 13/24 K.ILGVWDTAVSLGK.L sp|Q53RT3|APRV1_HUMAN 1 1357.7606 43.86 7392 20869 2 1357.757766 679.8876 Retroviral-like aspartic protease 1 OS=Homo sapiens OX=9606 GN=ASPRV1 PE=1 SV=1 5.84 3825.4 - 5.32E+06 - - - -2.0519 - 2.604 0.568 - 549.7 1 2 0 -0.0028 13 0 0 0 1.90E+07 4.33E+05 - - - 5.6917 1 230117_WJC_METTL3_WT_vs_EV_F01.20870.20870.2 8.12E-08 15/22 R.VPDGMVGLIIGR.G "sp|Q92945|FUBP2_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 1225.6853 2.2 7393 20870 2 1225.685006 613.8499 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.81 3825.5 - 4.98E+06 - - - -0.2219 - 2.543 0.608 - 997.3 1 2 0 -0.0003 12 0 0 0 3.55E+07 1.61E+07 - - - 5.9874 0.999 230117_WJC_METTL3_WT_vs_EV_F01.20871.20871.2 0.000529 14-Aug K.FGFYEVFK[136.11].V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1043.5208 1.05 7394 20871 2 1043.519228 522.7677 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3825.6 - 4.75E+06 - - - -1.4767 - 1.658 0.511 - 138 1 2 0 -0.0015 8 0 0 0 3.67E+07 3.49E+07 - - - 4.3397 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.20872.20872.2 0.0108 18-Aug K.YSDIDIILLK[136.11].G "sp|Q92973|TNPO1_HUMAN,tr|A0A7P0T9C0|A0A7P0T9C0_HUMAN,tr|A0A7P0TBF0|A0A7P0TBF0_HUMAN,tr|A0A7P0T944|A0A7P0T944_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 5 1199.6893 1.13 7395 20872 2 1199.688875 600.8519 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 4.21 3825.6 - 4.69E+06 - - - -0.3468 - 1.549 0.396 - 120.7 1 2 0 -0.0004 10 0 0 0 1.40E+07 1.24E+07 - - - 3.1872 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.20873.20873.2 0.0051 14-Sep K.FGFYEVFK.V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1035.5066 1.05 7396 20873 2 1035.505003 518.7606 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3825.7 - 4.56E+06 - - - -1.5123 - 1.721 0.433 - 187.4 1 2 0 -0.0016 8 0 0 0 3.67E+07 3.49E+07 - - - 3.876 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.20874.20874.2 0.0123 14-Sep R.ETILNLLR[166.11].K "sp|Q6P158|DHX57_HUMAN,tr|A0A087WZ11|A0A087WZ11_HUMAN" 2 980.5894 0.86 7397 20874 2 980.587486 491.302 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 6.1 3825.8 - 3.34E+06 - - - -1.9529 - 2.009 0.35 - 282.2 1 2 0 -0.0019 8 0 0 0 6.88E+06 8.04E+06 - - - 3.7295 1 230117_WJC_METTL3_WT_vs_EV_F01.20875.20875.2 2.42E-09 19/34 K.ILDSFAAAPVPTTTLVLK.S sp|P18583|SON_HUMAN 1 1856.0659 1.68 7398 20875 2 1856.066694 929.0402 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3825.9 - 3.16E+06 - - - 0.4267 - 3.456 0.619 - 713.1 1 2 0 0.0008 18 0 0 0 2.53E+07 1.51E+07 - - - 6.6616 1 230117_WJC_METTL3_WT_vs_EV_F01.20876.20876.2 1.73E-08 14/26 K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.17 7399 20876 2 1408.827583 705.4218 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3826.1 - 3.11E+06 - - - -0.9817 - 2.857 0.527 - 770.6 1 2 0 -0.0014 14 0 0 0 2.58E+08 2.22E+08 - - - 5.5673 0.9176 230117_WJC_METTL3_WT_vs_EV_F01.20877.20877.2 0.000441 20-Nov K.LTPLILK[136.11]PFGN.S "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1219.742 1.48 7400 20877 2 1219.741257 610.8783 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 8.75 3826.2 - 2.74E+06 - - - -0.605 - 1.659 0.368 - 412.2 1 1 0 -0.0007 11 0 0 0 3.17E+07 2.14E+07 - - - 3.1282 1 230117_WJC_METTL3_WT_vs_EV_F01.20878.20878.2 0.00304 20-Nov K.ILLTQENPFFR[166.11].K sp|Q08J23|NSUN2_HUMAN 1 1386.7535 2.31 7401 20878 2 1386.753759 694.384 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3826.3 - 2.49E+06 - - - 0.1824 - 2.558 0.438 - 460.4 1 2 0 0.0003 11 0 0 0 9.29E+07 4.02E+07 - - - 4.8168 1 230117_WJC_METTL3_WT_vs_EV_F01.20879.20879.2 3.71E-06 15/26 K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.17 7402 20879 2 1416.83869 709.4289 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3826.4 - 2.44E+06 - - - -3.1591 - 2.785 0.569 - 846.4 1 2 0 -0.0045 14 0 0 0 2.58E+08 2.22E+08 - - - 5.8125 1 230117_WJC_METTL3_WT_vs_EV_F01.20880.20880.2 5.59E-08 19/34 K.ILDSFAAAPVPTTTLVLK[136.11].S sp|P18583|SON_HUMAN 1 1864.0801 1.68 7403 20880 2 1864.076999 933.0473 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3826.5 - 2.31E+06 - - - -1.6646 - 3.449 0.607 - 707.7 1 2 0 -0.0031 18 0 0 0 2.53E+07 1.51E+07 - - - 6.5672 1 230117_WJC_METTL3_WT_vs_EV_F01.20885.20885.2 2.60E-06 18-Dec F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 7407 20885 2 1343.611765 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3827.2 - 1.09E+06 - - - 0.2255 - 2.616 0.618 - 539.5 1 1 0 0.0003 10 0 0 0 1.90E+07 0.00E+00 - - - 6.2897 0.9908 230117_WJC_METTL3_WT_vs_EV_F01.20886.20886.2 0.0125 16-Jun R.QVLLEIFSK.N "sp|Q9NVU0|RPC5_HUMAN,tr|A0A0C4DH01|A0A0C4DH01_HUMAN" 2 1075.6277 1.36 7408 20886 2 1075.625102 538.8211 DNA-directed RNA polymerase III subunit RPC5 OS=Homo sapiens OX=9606 GN=POLR3E PE=1 SV=1 6 3827.2 - 288176 - - - -2.459 - 1.257 0.323 - 62.9 1 2 0 -0.0026 9 0 0 0 3.79E+06 2.79E+06 - - - 2.0876 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.20887.20887.2 0.216 16-Aug K.TEILPPFFK[136.11].H sp|O75533|SF3B1_HUMAN 1 1098.6205 0.99 7409 20887 2 1098.621047 550.3175 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.66 3827.3 - 5.48E+06 - - - 0.5134 - 1.78 0.291 - 260.1 1 2 0 0.0006 9 0 0 0 6.27E+07 6.34E+07 - - - 2.8583 1 230117_WJC_METTL3_WT_vs_EV_F01.20893.20893.2 5.02E-05 22-Dec R.YGLFPANYVELR[166.11].Q sp|Q14247|SRC8_HUMAN 1 1450.7484 2.15 7415 20893 2 1450.746095 726.3815 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 6 3827.8 - 0 - - - -1.6033 - 2.426 0.485 - 340.1 1 2 0 -0.0023 12 0 0 0 1.70E+07 7.91E+06 - - - 4.9543 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20901.20901.2 0.000879 20-Nov K.LFTAESLIGLK.N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1190.6911 1.81 7421 20901 2 1190.691577 596.3528 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6 3828.8 - 6.55E+06 - - - 0.4216 - 2.112 0.418 - 358.4 1 2 0 0.0005 11 0 0 0 4.92E+07 2.72E+07 - - - 4.1507 0.9458 230117_WJC_METTL3_WT_vs_EV_F01.20902.20902.2 0.00523 20-Nov K.LTPLILKPFGN.S "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1211.7278 1.48 7422 20902 2 1211.728086 606.8712 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 8.75 3828.8 - 4.22E+06 - - - 0.2402 - 1.644 0.366 - 364.8 1 1 0 0.0003 11 0 0 0 3.17E+07 2.14E+07 - - - 3.089 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20903.20903.2 1.78E-06 18-Oct K.MPLIGLGTWK.S "sp|P14550|AK1A1_HUMAN,sp|P15121|ALDR_HUMAN,tr|V9GYG2|V9GYG2_HUMAN,tr|E9PCX2|E9PCX2_HUMAN,tr|Q5T621|Q5T621_HUMAN,tr|V9GYP9|V9GYP9_HUMAN,tr|E9PEF9|E9PEF9_HUMAN" 7 1114.6209 1.03 7423 20903 2 1114.622143 558.3177 Aldo-keto reductase family 1 member A1 OS=Homo sapiens OX=9606 GN=AKR1A1 PE=1 SV=3 8.5 3828.9 - 2.01E+06 - - - 1.1268 - 2.163 0.357 - 326.6 1 2 0 0.0013 10 0 0 0 1.73E+07 1.67E+07 - - - 3.8309 1 230117_WJC_METTL3_WT_vs_EV_F01.20905.20905.2 8.88E-06 18-Dec K.MPLIGLGTWK[136.11].S "sp|P14550|AK1A1_HUMAN,sp|P15121|ALDR_HUMAN,tr|V9GYG2|V9GYG2_HUMAN,tr|E9PCX2|E9PCX2_HUMAN,tr|Q5T621|Q5T621_HUMAN,tr|V9GYP9|V9GYP9_HUMAN,tr|E9PEF9|E9PEF9_HUMAN" 7 1122.6351 1.03 7425 20905 2 1122.637472 562.3248 Aldo-keto reductase family 1 member A1 OS=Homo sapiens OX=9606 GN=AKR1A1 PE=1 SV=3 8.5 3829.1 - 1.82E+06 - - - 2.1245 - 2.289 0.463 - 529.8 1 2 0 0.0024 10 0 0 0 1.73E+07 1.67E+07 - - - 4.7715 1 230117_WJC_METTL3_WT_vs_EV_F01.20906.20906.3 3.96E-07 17/52 K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.14 7426 20906 3 1408.829058 470.6169 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3829.2 - 1.77E+06 - - - 0.0653 - 3.133 0.587 - 380 1 2 0 0.0001 14 0 0 0 4.73E+07 4.15E+07 - - - 8.1193 1 230117_WJC_METTL3_WT_vs_EV_F01.20907.20907.3 7.33E-08 19/52 K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.14 7427 20907 3 1416.842232 473.2883 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3829.3 - 1.58E+06 - - - -0.6592 - 3.161 0.549 - 470.1 1 2 0 -0.0009 14 0 0 0 4.73E+07 4.15E+07 - - - 7.7191 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20908.20908.2 0.0125 13/22 K.ALLVEVQLLESK[136.11].T sp|O00231|PSD11_HUMAN 1 1348.8057 2.46 7428 20908 2 1348.806279 675.4101 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.53 3829.4 - 1.30E+06 - - - 0.4159 - 2.607 0.329 - 573.3 1 2 0 0.0006 12 0 0 0 1.54E+07 6.27E+06 - - - 3.992 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.20910.20910.2 0.0182 14-Sep K.TFFLEALR.G "sp|Q9H0R4|HDHD2_HUMAN,tr|K7ER15|K7ER15_HUMAN" 2 995.544 1.66 7430 20910 2 995.544396 498.7793 Haloacid dehalogenase-like hydrolase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=HDHD2 PE=1 SV=1 5.66 3829.7 - 1.22E+06 - - - 0.3807 - 1.606 0.383 - 307.9 1 2 0 0.0004 8 0 0 0 6.27E+06 3.78E+06 - - - 3.2985 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.20912.20912.2 4.32 20-Dec K.LLLIPQGAILR.A sp|Q9ULM3|YETS2_HUMAN 1 1205.786 6.46 7432 20912 2 1205.785357 603.9003 YEATS domain-containing protein 2 OS=Homo sapiens OX=9606 GN=YEATS2 PE=1 SV=2 9.75 3830 - 1.11E+06 - - - -0.5158 - 2.155 0.319 - 477.8 1 2 0 -0.0006 11 0 0 0 1.82E+07 2.83E+06 - - - 3.474 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.20913.20913.2 0.00358 14-Sep K.TFFLEALR[166.11].G "sp|Q9H0R4|HDHD2_HUMAN,tr|K7ER15|K7ER15_HUMAN" 2 1005.5523 1.66 7433 20913 2 1005.552163 503.7834 Haloacid dehalogenase-like hydrolase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=HDHD2 PE=1 SV=1 5.66 3830.1 - 1.01E+06 - - - -0.1233 - 1.438 0.316 - 299.3 1 2 0 -0.0001 8 0 0 0 6.27E+06 3.78E+06 - - - 2.4705 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20918.20918.2 0.000234 16-Sep R.GFAFVYFER[166.11].L sp|Q13595|TRA2A_HUMAN 1 1144.5581 0.86 7436 20918 2 1144.558345 573.2863 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3830.8 - 2.58E+07 - - - 0.2132 - 1.91 0.395 - 382.1 1 2 0 0.0002 9 0 0 0 5.46E+07 6.34E+07 - - - 3.8305 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.20919.20919.2 0.505 16-Oct R.GFAFVYFER.L sp|Q13595|TRA2A_HUMAN 1 1134.5498 0.86 7437 20919 2 1134.550089 568.2822 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3830.8 - 2.32E+07 - - - 0.2274 - 1.993 0.379 - 506.1 1 2 0 0.0003 9 0 0 0 5.46E+07 6.34E+07 - - - 3.8354 1 230117_WJC_METTL3_WT_vs_EV_F01.20921.20921.2 0.000698 16-Oct R.YLTVAAIFR.G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1052.6019 2.58 7439 20921 2 1052.601115 527.3082 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3830.9 - 1.47E+07 - - - -0.7135 - 1.889 0.531 - 341.2 1 2 0 -0.0008 9 0 0 0 2.72E+07 1.05E+07 - - - 4.8028 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.20922.20922.2 0.00011 16-Aug K.VSFLLPTLR.K "sp|Q9UFC0|LRWD1_HUMAN,tr|H7C5S6|H7C5S6_HUMAN" 2 1044.6332 1.52 7440 20922 2 1044.633257 523.3239 Leucine-rich repeat and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRWD1 PE=1 SV=2 9.72 3831 - 8.04E+06 - - - 0.0862 - 1.519 0.41 - 200.2 1 2 0 0.0001 9 0 0 0 1.49E+07 9.77E+06 - - - 3.2787 1 230117_WJC_METTL3_WT_vs_EV_F01.20923.20923.2 0.000662 16-Oct R.YLTVAAIFR[166.11].G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1062.6101 2.61 7441 20923 2 1062.611117 532.3123 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3831 - 5.60E+06 - - - 0.9232 - 1.935 0.495 - 347.2 1 2 0 0.001 9 0 0 0 2.77E+07 1.06E+07 - - - 4.6065 1 230117_WJC_METTL3_WT_vs_EV_F01.20924.20924.2 1.84E-06 14/24 K.MVFINNIALAQIK[136.11].N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1481.852 0.96 7442 20924 2 1481.850314 741.9333 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3831.1 - 4.92E+06 - - - -1.1081 - 2.781 0.562 - 562.9 1 2 0 -0.0016 13 0 0 0 1.42E+07 1.48E+07 - - - 5.8165 1 230117_WJC_METTL3_WT_vs_EV_F01.20926.20926.2 2.78E-11 14/24 K.MVFINNIALAQIK.N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1473.8378 0.96 7444 20926 2 1473.838284 737.9262 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3831.3 - 4.48E+06 - - - 0.3582 - 2.921 0.611 - 662.1 1 2 0 0.0005 13 0 0 0 1.42E+07 1.48E+07 - - - 6.3048 1 230117_WJC_METTL3_WT_vs_EV_F01.20929.20929.2 0.0294 13/26 R.LFLVGSSLNGFGTR.S "sp|Q6PIY7|GLD2_HUMAN,tr|D6RAF2|D6RAF2_HUMAN" 2 1466.7882 -1 7447 20929 2 1466.786656 734.4014 Poly(A) RNA polymerase GLD2 OS=Homo sapiens OX=9606 GN=TENT2 PE=1 SV=1 9.75 3831.6 - 2.08E+06 - - - -1.0281 - 2.609 0.505 - 368.5 1 2 0 -0.0015 14 0 0 0 0.00E+00 0.00E+00 - - - 5.1769 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.20930.20930.2 0.00233 14-Jul K.ETLLAMFK.Y sp|P26639|SYTC_HUMAN 1 951.5099 2.72 7448 20930 2 951.509679 476.7622 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 6.1 3831.7 - 2.05E+06 - - - -0.2743 - 1.58 0.476 - 155.8 1 2 0 -0.0003 8 0 0 0 4.28E+06 1.57E+06 - - - 3.9362 1 230117_WJC_METTL3_WT_vs_EV_F01.20931.20931.2 2.39E-08 14/26 K.ELIELTEASLVSVR.K "sp|Q8N5A5|ZGPAT_HUMAN,tr|X6RGY1|X6RGY1_HUMAN" 2 1557.8614 2.37 7449 20931 2 1557.864145 779.938 Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3 4.25 3831.8 - 1.91E+06 - - - 1.7697 - 3.116 0.547 - 732.5 1 2 0 0.0028 14 0 0 0 4.42E+06 1.87E+06 - - - 5.9324 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.20932.20932.2 0.00316 24-Dec R.ILFIGGITAPTVR[166.11].Q sp|P48651|PTSS1_HUMAN 1 1366.8212 -1 7450 20932 2 1366.819411 684.4179 Phosphatidylserine synthase 1 OS=Homo sapiens OX=9606 GN=PTDSS1 PE=1 SV=1 9.75 3832 - 1.75E+06 - - - -1.303 - 2.459 0.396 - 533.5 1 2 0 -0.0018 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2745 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20934.20934.2 1.52E-05 30-Dec K.LFVEALGQIGPAPPLK.V "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1648.9552 6.16 7452 20934 2 1648.957424 825.4849 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3832.2 - 1.43E+06 - - - 1.3311 - 1.787 0.486 - 202.4 1 2 0 0.0022 16 0 0 0 7.75E+06 1.26E+06 - - - 4.0572 1 230117_WJC_METTL3_WT_vs_EV_F01.20936.20936.2 4.23E-07 20-Oct R.GGYFDEFGIIR.D "sp|P11413|G6PD_HUMAN,tr|E7EM57|E7EM57_HUMAN,tr|E7EUI8|E7EUI8_HUMAN" 3 1272.6139 3.36 7454 20936 2 1272.616277 637.3142 Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4 4.37 3832.4 - 1.26E+06 - - - 1.8772 - 1.829 0.564 - 238.1 1 2 0 0.0024 11 0 0 0 4.02E+06 1.20E+06 - - - 4.8393 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.20937.20937.2 0.000861 12-Jul K.YPVWLWK.R "sp|Q13084|RM28_HUMAN,tr|A2IDC6|A2IDC6_HUMAN,tr|A2IDC7|A2IDC7_HUMAN,tr|Q4TT37|Q4TT37_HUMAN" 4 990.5327 0.58 7455 20937 2 990.531803 496.2736 "39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4" 8.59 3832.5 - 1.17E+06 - - - -0.9298 - 1.539 0.298 - 194.8 1 2 0 -0.0009 7 0 0 0 3.37E+06 5.79E+06 - - - 2.6078 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.20939.20939.2 4.89E-05 24-Sep K.TLLTFC[160.03]TNGVLLR.T "sp|Q9H6S0|YTDC2_HUMAN,tr|D6RA70|D6RA70_HUMAN" 2 1506.8228 1.91 7456 20939 2 1506.819679 754.4187 3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2 7.91 3832.7 - 232319 - - - -2.0945 - 1.87 0.461 - 212.6 1 2 0 -0.0032 13 0 0 0 2.50E+06 1.31E+06 - - - 4.0514 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.20941.20941.2 0.00607 16-Sep K.IGFPWSEIR[166.11].N "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 1113.5847 0.25 7458 20941 2 1113.586823 557.7996 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 6 3832.9 - 2.16E+06 - - - 1.9514 - 1.638 0.44 - 244.3 1 2 0 0.0022 9 0 0 0 1.29E+07 5.11E+07 - - - 3.7178 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.20943.20943.2 0.0013 16-Aug K.IGFPWSEIR.N "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 1103.5764 0.25 7460 20943 2 1103.576344 552.7955 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 6 3833.1 - 1.66E+06 - - - -0.0326 - 1.602 0.359 - 207.9 1 2 0 0 9 0 0 0 1.29E+07 5.06E+07 - - - 3.0559 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.20944.20944.2 1.23 14-Jul R.VIFGLFGK.T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 879.5218 0.68 7461 20944 2 879.521506 440.7682 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.72 3833.1 - 1.62E+06 - - - -0.3627 - 1.442 0.22 - 140.5 1 2 0 -0.0003 8 0 0 0 1.76E+07 2.61E+07 - - - 1.7698 1 230117_WJC_METTL3_WT_vs_EV_F01.20948.20948.2 4.07E-05 13/26 K.VLFLLGADGGC[160.03]ITR[166.11].Q "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1500.7998 -1 7465 20948 2 1500.806843 751.4072 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 5.8 3833.6 - 552161 - - - 4.6895 - 2.854 0.561 - 535.1 1 2 0 0.007 14 0 0 0 0.00E+00 0.00E+00 - - - 5.814 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.20950.20950.2 0.009 16-Sep K.IIAATFLFK.W sp|Q13907|IDI1_HUMAN 1 1022.6165 6.28 7467 20950 2 1022.617058 512.3155 Isopentenyl-diphosphate Delta-isomerase 1 OS=Homo sapiens OX=9606 GN=IDI1 PE=1 SV=2 8.75 3833.8 - 413932 - - - 0.5906 - 1.628 0.27 - 175.9 1 2 0 0.0006 9 0 0 0 3.86E+06 6.15E+05 - - - 2.445 0.9515 230117_WJC_METTL3_WT_vs_EV_F01.20951.20951.3 7.45E-07 Nov-36 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 7468 20951 3 1343.609093 448.8778 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3834 - 158875 - - - -1.7632 - 1.997 0.582 - 259.6 1 1 0 -0.0024 10 0 0 0 1.23E+06 0.00E+00 - - - 7.048 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.20966.20966.3 9.02E-07 14/60 R.TPEQVAEEEYLLQELR.K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1945.9633 1.5 7481 20966 3 1945.958184 649.6617 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3835.7 - 94682.4 - - - -2.6224 - 2.795 0.539 - 246 1 2 0 -0.0051 16 0 0 0 5.98E+06 3.97E+06 - - - 7.1852 1 230117_WJC_METTL3_WT_vs_EV_F01.20970.20970.3 1.21E-06 17/60 R.TPEQVAEEEYLLQELR[166.11].K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1955.9716 1.62 7485 20970 3 1955.965495 652.9978 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3836.2 - 69525.7 - - - -3.0992 - 2.873 0.577 - 362.2 1 2 0 -0.0061 16 0 0 0 7.83E+06 4.83E+06 - - - 7.6792 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.20971.20971.3 0.000359 Nov-48 K.MVFINNIALAQIK.N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1473.8378 0.87 7486 20971 3 1473.833532 492.2865 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3836.4 - 65653 - - - -2.866 - 2.135 0.366 - 202.2 1 2 0 -0.0042 13 0 0 0 2.97E+06 3.42E+06 - - - 4.6758 1 230117_WJC_METTL3_WT_vs_EV_F01.20973.20973.2 2.08E-06 30-Nov R.LIADLGSTSITNLGFR[166.11].D sp|Q92520|FAM3C_HUMAN 1 1686.918 -1 7488 20973 2 1686.910718 844.4663 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 5.84 3836.6 - 0 - - - -4.3197 - 2.288 0.527 - 339.2 1 2 0 -0.0073 16 0 0 0 0.00E+00 0.00E+00 - - - 4.966 1 230117_WJC_METTL3_WT_vs_EV_F01.20974.20974.2 5.37E-14 18/30 R.TPEQVAEEEYLLQELR.K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1945.9633 1.21 7489 20974 2 1945.958808 973.9889 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3836.7 - 0 - - - -2.3017 - 4.016 0.635 - 1182.3 1 2 0 -0.0045 16 0 0 0 5.38E+06 4.43E+06 - - - 7.1478 1 230117_WJC_METTL3_WT_vs_EV_F01.20975.20975.2 1.99E-07 14/24 K.VLGTAFDPFLGGK.N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1320.7078 8.94 7490 20975 2 1320.705774 661.3612 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3836.9 - 0 - - - -1.5249 - 2.387 0.595 - 462.8 1 2 0 -0.002 13 0 0 0 5.00E+08 5.59E+07 - - - 5.668 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.20977.20977.2 0.107 14-Aug K.LLELLWNK[136.11].Y "sp|Q92905|CSN5_HUMAN,tr|E5RHH5|E5RHH5_HUMAN" 2 1035.6208 -1 7491 20977 2 1035.619222 518.8177 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 6 3837.1 - 288299 - - - -1.5401 - 1.651 0.253 - 156.5 1 2 0 -0.0016 8 0 0 0 0.00E+00 0.00E+00 - - - 2.4213 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.20979.20979.2 0.00806 20-Oct K.ELGIWEPLAVK.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1253.702 10.06 7493 20979 2 1253.703278 627.8583 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3837.3 - 3.01E+06 - - - 1.0401 - 1.943 0.436 - 352 1 2 0 0.0013 11 0 0 0 1.37E+09 1.36E+08 - - - 4.0578 0.9921 230117_WJC_METTL3_WT_vs_EV_F01.20986.20986.2 0.00355 20-Oct K.ELGIWEPLAVK[136.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1261.7162 10.06 7497 20986 2 1261.712323 631.8654 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3837.9 - 4.01E+06 - - - -3.0522 - 1.918 0.247 - 369.4 1 2 0 -0.0039 11 0 0 0 1.37E+09 1.36E+08 - - - 2.626 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.20988.20988.2 0.00758 14-Aug K.EALLELLR.L sp|Q13895|BYST_HUMAN 1 955.5702 1.02 7499 20988 2 955.568746 478.7924 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3838 - 266391 - - - -1.5551 - 1.879 0.392 - 252.8 1 2 0 -0.0015 8 0 0 0 5.94E+07 5.85E+07 - - - 3.8381 1 230117_WJC_METTL3_WT_vs_EV_F01.20992.20992.2 3.69E-05 14/24 K.LLEQALVIEEQLR.R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1552.8825 1.57 7503 20992 2 1552.880272 777.4485 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3838.4 - 0 - - - -1.4077 - 3.12 0.506 - 856.8 1 2 0 -0.0022 13 0 0 0 2.87E+07 1.83E+07 - - - 5.6979 0.9093 230117_WJC_METTL3_WT_vs_EV_F01.20995.20995.2 8.44 12-Jun K.LWYVLLK.E sp|Q9HD33|RM47_HUMAN 1 933.5688 -1 7506 20995 2 933.567206 467.7917 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 8.59 3838.7 - 0 - - - -1.6806 - 1.202 0.038 - 89.5 1 2 0 -0.0016 7 0 0 0 0.00E+00 0.00E+00 - - - -0.0959 1 230117_WJC_METTL3_WT_vs_EV_F01.20997.20997.2 8.47E-05 15/24 K.LLEQALVIEEQLR[166.11].R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1562.8907 1.59 7508 20997 2 1562.886353 782.4526 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3838.9 - 474469 - - - -2.7993 - 2.736 0.416 - 1005.9 1 2 0 -0.0044 13 0 0 0 2.83E+07 1.78E+07 - - - 4.6954 1 230117_WJC_METTL3_WT_vs_EV_F01.21001.21001.2 2.65E-06 26-Nov K.LGLVGVNLTLDGVK[136.11].S "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 1404.8432 1.39 7510 21001 2 1404.84032 703.4289 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 3839.5 - 1.93E+06 - - - -2.0258 - 2.868 0.503 - 358.4 1 2 0 -0.0028 14 0 0 0 8.31E+07 5.99E+07 - - - 5.3993 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21003.21003.2 0.0162 14-Sep K.EALLELLR[166.11].L sp|Q13895|BYST_HUMAN 1 965.5785 1.02 7512 21003 2 965.579968 483.7965 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3839.6 - 3.30E+06 - - - 1.5183 - 2.02 0.358 - 334.8 1 2 0 0.0015 8 0 0 0 5.94E+07 5.85E+07 - - - 3.8052 1 230117_WJC_METTL3_WT_vs_EV_F01.21004.21004.2 4.63E-09 16/24 K.VLGTAFDPFLGGK[136.11].N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1328.722 9.04 7513 21004 2 1328.722482 665.3683 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3839.6 - 2.08E+06 - - - 0.3718 - 2.817 0.644 - 749.3 1 2 0 0.0005 13 0 0 0 5.07E+08 5.61E+07 - - - 6.4555 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21006.21006.3 3.04E-05 13/56 K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 0.75 7515 21006 3 1521.87983 508.2991 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3839.8 - 1.19E+06 - - - 2.903 - 2.309 0.359 - 294.2 1 2 0 0.0044 15 0 0 0 1.08E+07 1.43E+07 - - - 4.7248 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.21007.21007.2 1.56E-05 30-Sep R.IASLPVEVQEVSLLDK.L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1738.9717 2.73 7516 21007 2 1738.966304 870.4931 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.14 3839.8 - 0 - - - -3.084 - 1.798 0.517 - 179.1 1 2 0 -0.0054 16 0 0 0 4.19E+07 1.53E+07 - - - 4.3002 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21009.21009.2 0.00348 13/24 K.ALVLANPEVSLWR.K "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 1466.8245 1.19 7518 21009 2 1466.823928 734.4196 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6.05 3839.9 - 297684 - - - -0.4234 - 2.595 0.409 - 639.2 1 2 0 -0.0006 13 0 0 0 1.17E+07 9.83E+06 - - - 4.5091 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21010.21010.2 0.00142 20-Nov K.SLPASLSFLVK.L "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN" 5 1160.6805 -1 7519 21010 2 1160.682792 581.3475 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 8.47 3840 - 389708 - - - 1.9652 - 1.823 0.432 - 239 1 2 0 0.0023 11 0 0 0 0.00E+00 0.00E+00 - - - 3.8555 1 230117_WJC_METTL3_WT_vs_EV_F01.21012.21012.2 1.12E-06 13/28 R.LISEILSESVVPDVR.S "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 11 1654.9142 -1 7521 21012 2 1654.905193 828.4644 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.14 3840.2 - 0 - - - -5.4136 - 2.814 0.584 - 513.7 1 2 0 -0.009 15 0 0 0 0.00E+00 0.00E+00 - - - 5.8952 1 230117_WJC_METTL3_WT_vs_EV_F01.21013.21013.2 3.73E-08 14/30 R.LPC[160.03]IYLVDSGGAYLPR.Q "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJW5|A0A804HJW5_HUMAN,tr|A0A0G2JM88|A0A0G2JM88_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HIH3|A0A804HIH3_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|D6RDF7|D6RDF7_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HJW2|A0A804HJW2_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|D6R9R1|D6R9R1_HUMAN,tr|A0A804HHS4|A0A804HHS4_HUMAN,tr|A0A0S2Z5R4|A0A0S2Z5R4_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 16 1792.9182 2.14 7522 21013 2 1792.911065 897.4664 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.83 3840.3 - 0 - - - -3.9751 - 3.043 0.663 - 618.2 1 2 0 -0.0071 16 0 0 0 4.67E+06 2.19E+06 - - - 6.6717 1 230117_WJC_METTL3_WT_vs_EV_F01.21016.21016.2 8.69E-05 28-Dec R.LISEILSESVVPDVR[166.11].S "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 11 1664.9224 1.52 7525 21016 2 1664.918523 833.4685 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.14 3840.7 - 0 - - - -2.3419 - 2.551 0.539 - 323.4 1 2 0 -0.0039 15 0 0 0 4.03E+06 2.65E+06 - - - 5.3232 1 230117_WJC_METTL3_WT_vs_EV_F01.21017.21017.2 1.56E-07 14/26 K.NLPIYSEEIVEMYK.G "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1726.8488 3.04 7526 21017 2 1726.84407 864.4317 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3840.9 - 0 - - - -2.7246 - 2.972 0.613 - 505.7 1 2 0 -0.0047 14 0 0 0 1.80E+07 5.94E+06 - - - 6.3005 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.21018.21018.2 0.00379 24-Aug K.LTSTVMLWLQTNK.S "sp|P47756|CAPZB_HUMAN,tr|B1AK87|B1AK87_HUMAN,tr|B1AK88|B1AK88_HUMAN,tr|B1AK85|B1AK85_HUMAN" 4 1533.8225 -1 7527 21018 2 1533.824985 767.9185 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4 8.75 3841 - 0 - - - 1.6201 - 1.284 0.334 - 74.8 1 2 0 0.0025 13 0 0 0 0.00E+00 0.00E+00 - - - 2.1487 1 230117_WJC_METTL3_WT_vs_EV_F01.21025.21025.2 0.00025 22-Dec K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 1.27 7531 21025 2 1314.79009 658.4028 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3841.9 - 2.38E+07 - - - -0.7864 - 2.313 0.533 - 512.3 1 2 0 -0.001 12 0 0 0 2.05E+08 1.61E+08 - - - 5.1838 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21026.21026.2 4.04E-05 20-Nov K.LLPAITILGC[160.03]R.V "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 2 1225.7217 2.49 7532 21026 2 1225.72271 613.8681 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 8.25 3842 - 5.08E+06 - - - 0.8534 - 2.082 0.391 - 425 1 2 0 0.001 11 0 0 0 3.11E+07 1.25E+07 - - - 3.9124 1 230117_WJC_METTL3_WT_vs_EV_F01.21027.21027.2 8.01E-10 18/28 K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 0.77 7533 21027 2 1521.872576 761.945 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3842.1 - 3.84E+06 - - - -1.8635 - 3.116 0.626 - 988.8 1 2 0 -0.0028 15 0 0 0 1.66E+07 2.15E+07 - - - 6.458 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.21028.21028.3 4.67E-05 13/48 K.LLEQALVIEEQLR.R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1552.8825 1.56 7534 21028 3 1552.881815 518.6348 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3842.2 - 3.76E+06 - - - -0.4141 - 2.711 0.454 - 268.6 1 2 0 -0.0006 13 0 0 0 1.68E+07 1.08E+07 - - - 6.3055 1 230117_WJC_METTL3_WT_vs_EV_F01.21029.21029.2 9.28E-10 20/28 K.TVAGQDAVIVLLGTR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1511.8671 0.77 7535 21029 2 1511.864802 756.9408 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3842.3 - 3.06E+06 - - - -1.5478 - 3.258 0.667 - 1233.8 1 2 0 -0.0023 15 0 0 0 1.66E+07 2.15E+07 - - - 6.8705 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.21030.21030.3 8.32E-08 18/56 K.TVAGQDAVIVLLGTR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1511.8671 0.44 7536 21030 3 1511.866476 504.963 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3842.4 - 2.53E+06 - - - -0.4405 - 2.882 0.526 - 540.9 1 2 0 -0.0007 15 0 0 0 1.10E+07 2.49E+07 - - - 7.1662 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.21031.21031.3 0.000483 14/48 K.LLEQALVIEEQLR[166.11].R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1562.8907 1.56 7537 21031 3 1562.89337 521.9709 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3842.6 - 2.39E+06 - - - 1.6905 - 2.557 0.345 - 360.6 1 2 0 0.0026 13 0 0 0 1.68E+07 1.08E+07 - - - 4.9311 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21033.21033.2 0.00854 13/24 K.ALVLANPEVSLWR.K "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 1466.8245 1.19 7539 21033 2 1466.824832 734.4196 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6.05 3842.8 - 2.04E+06 - - - 0.1929 - 2.425 0.33 - 575.3 1 2 0 0.0003 13 0 0 0 1.17E+07 9.83E+06 - - - 3.7518 1 230117_WJC_METTL3_WT_vs_EV_F01.21034.21034.2 0.00146 22-Oct R.LALFNPDVC[160.03]WDR.N sp|O00483|NDUA4_HUMAN 1 1504.7133 2.57 7540 21034 2 1504.711069 753.3639 Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1 4.21 3842.9 - 1.74E+06 - - - -1.472 - 2.346 0.481 - 375.6 1 2 0 -0.0022 12 0 0 0 1.50E+07 5.84E+06 - - - 4.8366 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.21035.21035.2 0.0204 24-Nov K.ALVLANPEVSLWR[166.11].K "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 1476.8328 1.19 7541 21035 2 1476.829987 739.4237 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6.05 3843.1 - 1.38E+06 - - - -1.9176 - 2.258 0.26 - 495.3 1 2 0 -0.0028 13 0 0 0 1.17E+07 9.83E+06 - - - 3.0509 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.21037.21037.2 0.00648 18-Oct K.EFLFNPYLTR[166.11].K "sp|P13378|HXD8_HUMAN,sp|P31273|HXC8_HUMAN,sp|P17481|HXB8_HUMAN,tr|I3L3R1|I3L3R1_HUMAN,tr|I3L383|I3L383_HUMAN,tr|A0A0A0MSX5|A0A0A0MSX5_HUMAN,tr|A0A0A0MTF4|A0A0A0MTF4_HUMAN" 7 1308.6742 1.37 7543 21037 2 1308.672896 655.3444 Homeobox protein Hox-D8 OS=Homo sapiens OX=9606 GN=HOXD8 PE=1 SV=2 6.1 3843.3 - 1.23E+06 - - - -0.9911 - 1.667 0.294 - 258.7 1 2 0 -0.0013 10 0 0 0 1.50E+07 1.10E+07 - - - 2.6385 1 230117_WJC_METTL3_WT_vs_EV_F01.21038.21038.2 1.14E-08 15/24 R.LGSTIFVANLDFK.V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1423.7711 1.86 7544 21038 2 1423.769957 712.8928 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3843.4 - 1.03E+06 - - - -0.8147 - 3.163 0.559 - 924.8 1 2 0 -0.0012 13 0 0 0 5.50E+07 2.95E+07 - - - 6.1248 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21044.21044.3 0.00139 Dec-44 K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 1.39 7550 21044 3 1314.789768 439.271 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3844.2 - 773196 - - - -1.0313 - 2.246 0.417 - 206.2 1 2 0 -0.0014 12 0 0 0 3.46E+06 2.48E+06 - - - 5.4316 1 230117_WJC_METTL3_WT_vs_EV_F01.21051.21051.2 3.24E-09 16/24 R.LGSTIFVANLDFK[136.11].V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1431.7853 1.88 7556 21051 2 1431.784724 716.8999 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3845 - 677923 - - - -0.4142 - 3.185 0.561 - 1068.7 1 2 0 -0.0006 13 0 0 0 5.45E+07 2.90E+07 - - - 6.1576 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.21054.21054.2 0.00777 18-Jul K.EFLFNPYLTR.K "sp|P13378|HXD8_HUMAN,sp|P31273|HXC8_HUMAN,sp|P17481|HXB8_HUMAN,tr|I3L3R1|I3L3R1_HUMAN,tr|I3L383|I3L383_HUMAN,tr|A0A0A0MSX5|A0A0A0MSX5_HUMAN,tr|A0A0A0MTF4|A0A0A0MTF4_HUMAN" 7 1298.6659 1.35 7559 21054 2 1298.667453 650.3402 Homeobox protein Hox-D8 OS=Homo sapiens OX=9606 GN=HOXD8 PE=1 SV=2 6.1 3845.3 - 227601 - - - 1.1781 - 1.674 0.31 - 148.4 1 2 0 0.0015 10 0 0 0 1.48E+07 1.10E+07 - - - 2.7683 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.21060.21060.2 0.00725 20-Aug R.QLLEEMLTSYR[166.11].L sp|O75688|PPM1B_HUMAN 1 1391.6994 0.49 7563 21060 2 1391.697528 696.857 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3846.1 - 4.43E+06 - - - -1.3609 - 2.08 0.36 - 277.1 1 2 0 -0.0019 11 0 0 0 5.80E+07 1.18E+08 - - - 3.6806 0.9961 230117_WJC_METTL3_WT_vs_EV_F01.21061.21061.2 0.236 20-Jul K.TLPLFYGSIVR[166.11].F "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1274.7262 1.33 7564 21061 2 1274.72599 638.3704 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 8.41 3846.2 - 4.42E+06 - - - -0.1875 - 1.49 0.197 - 166.5 1 2 0 -0.0002 11 0 0 0 3.65E+07 2.75E+07 - - - 1.5748 0.9769 230117_WJC_METTL3_WT_vs_EV_F01.21063.21063.2 4.16 20-Jun K.VPPPWLIAMQR.Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1306.722 0.99 7566 21063 2 1306.724755 654.3683 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3846.3 - 3.95E+06 - - - 2.1099 - 1.064 0.107 - 68.6 1 2 0 0.0028 11 0 0 0 1.66E+07 1.68E+07 - - - -0.0017 0.9981 230117_WJC_METTL3_WT_vs_EV_F01.21066.21066.2 0.00818 14-Aug R.QVLPFLLR.R "sp|O14981|BTAF1_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 2 984.612 1.66 7569 21066 2 984.610752 493.3133 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 9.75 3846.5 - 2.27E+06 - - - -1.3051 - 1.658 0.33 - 270.7 1 2 0 -0.0013 8 0 0 0 5.54E+06 3.34E+06 - - - 3.0029 0.8551 230117_WJC_METTL3_WT_vs_EV_F01.21073.21073.2 0.595 18-Jun K.GYGFVSFFNK.W "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN" 4 1164.5604 1.06 7576 21073 2 1164.555094 583.2875 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 8.59 3847.1 - 1.40E+06 - - - -4.5519 - 1.136 0.186 - 100.9 1 2 0 -0.0053 10 0 0 0 6.68E+06 6.27E+06 - - - 0.7691 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21074.21074.2 9.92E-06 30-Oct R.IASLPVEVQEVSLLDK[136.11].L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1746.9859 2.73 7577 21074 2 1746.988065 874.5002 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.14 3847.3 - 772839 - - - 1.2582 - 2.149 0.49 - 237.2 1 2 0 0.0022 16 0 0 0 4.19E+07 1.53E+07 - - - 4.5402 0.9473 230117_WJC_METTL3_WT_vs_EV_F01.21076.21076.2 3.46 22-May R.QALMPTLEALYR.Q "sp|Q92793|CBP_HUMAN,sp|Q09472|EP300_HUMAN,tr|A0A669KB12|A0A669KB12_HUMAN,tr|I3L466|I3L466_HUMAN" 4 1404.7435 -1 7579 21076 2 1404.747711 703.379 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 6 3847.4 - 660916 - - - 2.982 - 1.266 0.011 - 83.7 1 2 0 0.0042 12 0 0 0 0.00E+00 0.00E+00 - - - -0.2585 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.21077.21077.2 1.57E-05 24-Sep R.QMDIIVSEVSMIR[166.11].D "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1529.7821 -1 7580 21077 2 1529.779096 765.8983 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.37 3847.5 - 474394 - - - -1.9676 - 1.922 0.432 - 236.4 1 2 0 -0.003 13 0 0 0 0.00E+00 0.00E+00 - - - 3.9077 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21080.21080.2 1.37E-05 22-Jul R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 3982.21 7582 21080 2 1603.763662 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3847.9 - 3.09E+08 - - - -0.1733 - 1.66 0.549 - 135.9 1 2 0 -0.0003 12 0 0 0 2.77E+09 6.95E+05 - - - 4.4293 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21083.21083.2 1.82E-05 16-Aug R.MLYVWALC[160.03]R.D "sp|O43615|TIM44_HUMAN,tr|M0QXM9|M0QXM9_HUMAN" 2 1210.5991 2.43 7583 21083 2 1210.600008 606.3068 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 7.98 3848.1 - 584448 - - - 0.7451 - 1.826 0.37 - 309.9 1 2 0 0.0009 9 0 0 0 1.39E+07 5.71E+06 - - - 3.5155 0.9928 230117_WJC_METTL3_WT_vs_EV_F01.21085.21085.2 0.00028 16-Nov K.TLDDLFPLR.S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1088.5866 1.82 7585 21085 2 1088.581977 545.3006 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.21 3848.2 - 393135 - - - -4.256 - 1.795 0.421 - 429.6 1 2 0 -0.0046 9 0 0 0 4.31E+07 2.37E+07 - - - 3.8415 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.21086.21086.2 0.00334 18-Sep K.ADLGALELWR.T sp|Q99523|SORT_HUMAN 1 1142.6084 102.37 7586 21086 2 1142.606487 572.3115 Sortilin OS=Homo sapiens OX=9606 GN=SORT1 PE=1 SV=3 4.37 3848.3 - 0 - - - -1.6812 - 1.909 0.397 - 175.8 1 2 0 -0.0019 10 0 0 0 3.44E+06 3.37E+04 - - - 3.7774 1 230117_WJC_METTL3_WT_vs_EV_F01.21095.21095.2 7.67E-06 14/26 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.94 7593 21095 2 1669.895686 835.9552 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3849.5 - 282266 - - - -0.1461 - 2.403 0.565 - 571.5 1 2 0 -0.0002 14 0 0 0 2.67E+08 2.83E+08 - - - 5.4141 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.21102.21102.3 0.0403 Jul-40 K.VPPPWLIAMQR.Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1306.722 1.65 7600 21102 3 1306.724757 436.5813 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3850.4 - 161458 - - - 2.1114 - 1.716 0.273 - 94.3 1 2 0 0.0028 11 0 0 0 4.00E+06 2.42E+06 - - - 3.117 1 230117_WJC_METTL3_WT_vs_EV_F01.21103.21103.2 9.17E-10 13/26 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.94 7601 21103 2 1661.885889 831.9481 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3850.6 - 137646 - - - 2.5026 - 2.52 0.578 - 501.5 1 2 0 0.0042 14 0 0 0 2.67E+08 2.83E+08 - - - 5.6282 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21104.21104.3 0.0012 Oct-40 K.VPPPWLIAMQR[166.11].Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1316.7303 1.24 7602 21104 3 1316.733325 439.9174 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3850.7 - 131021 - - - 2.3217 - 2.01 0.345 - 158.4 1 2 0 0.0031 11 0 0 0 2.07E+06 1.67E+06 - - - 4.3688 1 230117_WJC_METTL3_WT_vs_EV_F01.21111.21111.3 7.90E-06 19/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 7608 21111 3 1603.768946 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3851.6 - 1.21E+08 - - - 3.1214 - 2.98 0.589 - 515.7 1 2 0 0.005 12 0 0 0 7.58E+08 0.00E+00 - - - 8.132 1 230117_WJC_METTL3_WT_vs_EV_F01.21112.21112.2 0.000186 16-Oct R.MLYVWALC[160.03]R[166.11].D "sp|O43615|TIM44_HUMAN,tr|M0QXM9|M0QXM9_HUMAN" 2 1220.6074 2.35 7609 21112 2 1220.607774 611.311 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 7.98 3851.7 - 916638 - - - 0.3261 - 2.103 0.528 - 410.7 1 2 0 0.0004 9 0 0 0 1.37E+07 5.82E+06 - - - 5.0913 1 230117_WJC_METTL3_WT_vs_EV_F01.21114.21114.2 9.02E-05 20-Dec K.VAVFFGGLSIK[136.11].K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1144.6736 0.84 7611 21114 2 1144.67257 573.3441 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3851.9 - 4.03E+06 - - - -0.8832 - 2.212 0.497 - 454.2 1 2 0 -0.001 11 0 0 0 4.20E+07 5.00E+07 - - - 4.8592 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.21115.21115.2 0.0237 16-Oct K.TLDDLFPLR[166.11].S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1098.5949 1.9 7612 21115 2 1098.594325 550.3047 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.21 3852 - 4.01E+06 - - - -0.5052 - 1.991 0.326 - 311.2 1 2 0 -0.0006 9 0 0 0 4.28E+07 2.26E+07 - - - 3.4409 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.21116.21116.2 0.00164 16-Oct K.ITFLLQAIR.N "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1073.6597 1.41 7613 21116 2 1073.65768 537.8371 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 3852.1 - 9.45E+06 - - - -1.8963 - 2.017 0.435 - 267 1 2 0 -0.002 9 0 0 0 5.10E+07 3.61E+07 - - - 4.2831 1 230117_WJC_METTL3_WT_vs_EV_F01.21120.21120.2 3.14E-06 24-Dec R.VLLFTDDVALVSK.A "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1418.8021 1.48 7617 21120 2 1418.801333 710.4083 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.21 3852.6 - 2.20E+06 - - - -0.5279 - 2.722 0.609 - 414.2 1 2 0 -0.0008 13 0 0 0 1.25E+07 8.44E+06 - - - 6.1089 1 230117_WJC_METTL3_WT_vs_EV_F01.21121.21121.3 7.73E-11 16/56 R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 1.31 7618 21121 3 2001.972857 668.3319 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3852.7 - 2.18E+06 - - - -0.4376 - 3.412 0.629 - 537.4 1 2 0 -0.0009 15 0 0 0 5.25E+06 4.02E+06 - - - 8.755 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.21123.21123.2 0.00113 22-Dec K.TLQTISLLGYMK.H sp|O60264|SMCA5_HUMAN 1 1366.753 1.19 7620 21123 2 1366.751592 684.3838 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 8.26 3853 - 1.23E+06 - - - -1.0477 - 2.015 0.405 - 341.5 1 2 0 -0.0014 12 0 0 0 6.41E+06 5.37E+06 - - - 3.8753 0.9376 230117_WJC_METTL3_WT_vs_EV_F01.21125.21125.2 0.763 26-Aug K.NLPIYSEEIVEMYK[136.11].G "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1734.863 -1 7622 21125 2 1734.858273 868.4388 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3853.2 - 663167 - - - -2.7103 - 1.142 0.168 - 67.7 1 2 0 -0.0047 14 0 0 0 0.00E+00 0.00E+00 - - - 0.6136 1 230117_WJC_METTL3_WT_vs_EV_F01.21128.21128.2 1.70E-09 14/28 R.HFYWYLTNEGIQYLR[166.11].D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2011.982 -1 7625 21128 2 2011.980808 1006.9983 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3853.6 - 407671 - - - -0.5939 - 2.519 0.615 - 525 1 2 0 -0.0012 15 0 0 0 0.00E+00 0.00E+00 - - - 5.8544 1 230117_WJC_METTL3_WT_vs_EV_F01.21132.21132.2 4.33E-08 13/20 R.DINAVLIDMER.Q "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1287.6493 1.5 7628 21132 2 1287.6392 644.8319 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.03 3854.1 - 1.70E+06 - - - -7.8337 - 2.615 0.582 - 824.6 1 2 0 -0.0101 11 0 0 0 1.74E+07 1.16E+07 - - - 5.9369 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21134.21134.2 0.00291 14-Aug R.DFLLDIAR.Q "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 961.5233 1.41 7630 21134 2 961.523863 481.7689 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 3854.2 - 1.74E+06 - - - 0.6042 - 1.54 0.406 - 307.7 1 2 0 0.0006 8 0 0 0 6.01E+07 4.26E+07 - - - 3.3418 0.9963 230117_WJC_METTL3_WT_vs_EV_F01.21136.21136.2 0.0832 14-Jul R.DFLLDIAR[166.11].Q "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 971.5316 1.41 7632 21136 2 971.532456 486.7731 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 3854.5 - 1.51E+06 - - - 0.9305 - 1.368 0.169 - 199.3 1 2 0 0.0009 8 0 0 0 6.02E+07 4.28E+07 - - - 1.234 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21137.21137.2 0.000502 24-Dec K.AAILPTSIFLTNK[136.11].K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1395.8217 0.48 7633 21137 2 1395.82359 698.9181 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3854.6 - 1.46E+06 - - - 1.3526 - 2.106 0.456 - 390.8 1 2 0 0.0019 13 0 0 0 7.40E+07 1.54E+08 - - - 4.3199 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.21138.21138.2 0.0612 20-Dec K.VPPPWLIAMQR[166.11].Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1316.7303 0.39 7634 21138 2 1316.730108 659.3724 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3854.7 - 1.12E+06 - - - -0.1215 - 1.746 0.236 - 489.2 1 2 0 -0.0002 11 0 0 0 4.56E+06 1.17E+07 - - - 2.2917 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21139.21139.2 0.0394 18-Dec R.MALLATVLGR.F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1043.6161 2.13 7635 21139 2 1043.616958 522.8153 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.5 3854.8 - 1.07E+06 - - - 0.7876 - 2.428 0.415 - 662.1 1 2 0 0.0008 10 0 0 0 6.44E+07 3.02E+07 - - - 4.582 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.21140.21140.3 3.91E-05 Nov-48 K.GFVHPDPLWIPFK.E "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 1551.8238 1.31 7636 21140 3 1551.824986 518.2819 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 6.74 3854.9 - 1.00E+06 - - - 0.7507 - 1.82 0.212 - 153.7 1 2 0 0.0012 13 0 0 0 4.64E+06 3.56E+06 - - - 2.5269 1 230117_WJC_METTL3_WT_vs_EV_F01.21141.21141.2 8.89E-06 24-Dec R.VLLFTDDVALVSK[136.11].A "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1426.8163 1.48 7637 21141 2 1426.821228 714.4154 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.21 3855.1 - 949315 - - - 3.4665 - 2.614 0.486 - 408.8 1 2 0 0.0049 13 0 0 0 1.25E+07 8.44E+06 - - - 5.0952 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.21143.21143.3 0.00375 Dec-44 R.EGFLDTLVVLHR.A "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 1397.7667 0.91 7639 21143 3 1397.764564 466.9295 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.32 3855.3 - 806492 - - - -1.5282 - 2.018 0.325 - 130 1 2 0 -0.0021 12 0 0 0 2.43E+06 2.67E+06 - - - 4.109 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21152.21152.2 0.023 18-Oct R.SDLVLLYELK[136.11].Q sp|Q9NPF5|DMAP1_HUMAN 1 1199.6893 1.24 7647 21152 2 1199.689675 600.8519 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.37 3856.4 - 2.03E+07 - - - 0.3201 - 2.14 0.39 - 329.6 1 2 0 0.0004 10 0 0 0 6.15E+07 4.96E+07 - - - 4.0451 1 230117_WJC_METTL3_WT_vs_EV_F01.21154.21154.2 0.000559 18-Sep R.DFILPISDVR.A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|Q4VXM0|Q4VXM0_HUMAN,tr|Q4VXM1|Q4VXM1_HUMAN" 5 1173.6394 3 7649 21154 2 1173.638316 587.827 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.21 3856.6 - 2.76E+07 - - - -0.9015 - 2.034 0.515 - 367.1 1 2 0 -0.0011 10 0 0 0 6.16E+07 2.05E+07 - - - 4.8263 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.21155.21155.2 0.00272 16-Oct K.ITFLLQAIR[166.11].N "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1083.668 1.42 7650 21155 2 1083.66786 542.8413 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 3856.6 - 1.63E+07 - - - -0.1163 - 1.877 0.26 - 378.8 1 2 0 -0.0001 9 0 0 0 5.13E+07 3.61E+07 - - - 2.783 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.21156.21156.3 7.60E-05 Dec-52 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.88 7651 21156 3 1669.894849 557.6393 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3856.6 - 1.19E+07 - - - -0.6473 - 2.034 0.47 - 188.2 1 2 0 -0.0011 14 0 0 0 3.01E+07 3.42E+07 - - - 5.6666 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21158.21158.3 0.000437 Oct-52 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.88 7653 21158 3 1661.87953 554.9679 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3856.7 - 9.68E+06 - - - -1.3238 - 2.018 0.476 - 117.8 1 2 0 -0.0022 14 0 0 0 3.01E+07 3.42E+07 - - - 5.7122 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.21159.21159.2 0.00625 18-Aug R.DFILPISDVR[166.11].A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|Q4VXM0|Q4VXM0_HUMAN,tr|Q4VXM1|Q4VXM1_HUMAN" 5 1183.6476 3 7654 21159 2 1183.646516 592.8311 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.21 3856.8 - 8.54E+06 - - - -0.953 - 1.813 0.455 - 243.8 1 2 0 -0.0011 10 0 0 0 6.16E+07 2.05E+07 - - - 4.0621 0.9947 230117_WJC_METTL3_WT_vs_EV_F01.21160.21160.2 0.058 16-May R.YSFIQALVR.R sp|Q92621|NU205_HUMAN 1 1095.6077 1.5 7655 21160 2 1095.606716 548.8111 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 8.75 3856.8 - 8.51E+06 - - - -0.8799 - 1.255 0.266 - 74.3 1 2 0 -0.001 9 0 0 0 1.96E+07 1.31E+07 - - - 1.6625 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.21163.21163.2 0.000716 20-Sep R.TSLGNVVLLLK[136.11].S "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1163.7369 1.42 7658 21163 2 1163.736097 582.8757 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 8.41 3857 - 6.94E+06 - - - -0.6986 - 2.016 0.389 - 206.7 1 2 0 -0.0008 11 0 0 0 3.17E+07 2.22E+07 - - - 3.8106 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21165.21165.2 0.00469 24-Oct K.IAVPLIQGYTVLR[166.11].L sp|Q8IW92|GLBL2_HUMAN 1 1451.874 0.86 7660 21165 2 1451.873818 726.9443 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3857.1 - 4.44E+06 - - - -0.095 - 1.992 0.422 - 343.1 1 2 0 -0.0001 13 0 0 0 1.17E+07 1.36E+07 - - - 3.9265 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21166.21166.2 0.000323 24-Sep K.IAVPLIQGYTVLR.L sp|Q8IW92|GLBL2_HUMAN 1 1441.8657 0.86 7661 21166 2 1441.867366 721.9401 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3857.1 - 3.78E+06 - - - 1.1652 - 1.861 0.451 - 167.3 1 2 0 0.0017 13 0 0 0 1.17E+07 1.37E+07 - - - 3.9657 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.21168.21168.2 0.0359 24-Jul K.LIHIPINNIIVGG.- sp|P60059|SC61G_HUMAN 1 1371.8238 - 7663 21168 2 1371.825636 686.9192 Protein transport protein Sec61 subunit gamma OS=Homo sapiens OX=9606 GN=SEC61G PE=1 SV=1 6.74 3857.3 - 2.83E+06 - - - 1.3231 - 1.627 0.276 - 93.7 1 2 0 0.0018 13 0 0 0 - - - - - 2.3282 1 230117_WJC_METTL3_WT_vs_EV_F01.21173.21173.2 1.02E-05 15/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 7667 21173 2 1343.607001 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3857.7 - 1.48E+06 - - - -3.3202 - 2.77 0.549 - 881.8 1 1 0 -0.0045 10 0 0 0 2.29E+07 0.00E+00 - - - 5.9384 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.21174.21174.2 0.000885 20-Sep K.YNVEAVELLIR[166.11].N "sp|A5YKK6|CNOT1_HUMAN,tr|H3BMZ2|H3BMZ2_HUMAN" 2 1327.7375 2.14 7668 21174 2 1327.737736 664.876 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.53 3857.9 - 872691 - - - 0.1612 - 1.761 0.391 - 281.3 1 2 0 0.0002 11 0 0 0 1.45E+07 6.77E+06 - - - 3.4597 1 230117_WJC_METTL3_WT_vs_EV_F01.21175.21175.2 4.11E-06 24-Nov K.AAILPTSIFLTNK.K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1387.8075 0.48 7669 21175 2 1387.807364 694.911 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3857.9 - 1.44E+07 - - - -0.0994 - 2.295 0.514 - 306.3 1 2 0 -0.0001 13 0 0 0 7.40E+07 1.54E+08 - - - 4.9695 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.21176.21176.2 0.0139 20-Oct R.TSLGNVVLLLK.S "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1155.7227 1.42 7670 21176 2 1155.721794 578.8686 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 8.41 3857.9 - 6.89E+06 - - - -0.7926 - 2.288 0.408 - 313.5 1 2 0 -0.0009 11 0 0 0 3.17E+07 2.22E+07 - - - 4.2933 1 230117_WJC_METTL3_WT_vs_EV_F01.21177.21177.2 1.50E-09 22-Nov K.ITAEEMYDIFGK.Y sp|Q9Y3B4|SF3B6_HUMAN 1 1415.6643 1.99 7671 21177 2 1415.662982 708.8394 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.14 3858 - 4.00E+06 - - - -0.9084 - 2.472 0.632 - 433.4 1 2 0 -0.0013 12 0 0 0 1.72E+07 8.63E+06 - - - 6.0898 1 230117_WJC_METTL3_WT_vs_EV_F01.21181.21181.2 0.000556 20-Dec R.FDEISFVNFAR[166.11].G sp|Q08945|SSRP1_HUMAN 1 1353.6593 0.61 7675 21181 2 1353.658606 677.8369 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3858.4 - 1.78E+06 - - - -0.4913 - 2.362 0.45 - 653.5 1 2 0 -0.0007 11 0 0 0 9.34E+06 1.52E+07 - - - 4.6897 1 230117_WJC_METTL3_WT_vs_EV_F01.21182.21182.2 4.35E-06 20-Dec R.WPDPEDLLTPR.W sp|Q8TAE8|G45IP_HUMAN 1 1337.6616 1.53 7676 21182 2 1337.662928 669.8381 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.03 3858.5 - 1.71E+06 - - - 1.0182 - 2.337 0.534 - 585.2 1 2 0 0.0014 11 0 0 0 8.45E+06 5.54E+06 - - - 5.2811 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.21183.21183.2 0.0143 16-Jul R.DIVQFVPFR.E "sp|Q96FN4|CPNE2_HUMAN,sp|O75131|CPNE3_HUMAN,sp|O95741|CPNE6_HUMAN,sp|Q86YQ8|CPNE8_HUMAN,sp|Q8IYJ1|CPNE9_HUMAN,sp|Q9UBL6|CPNE7_HUMAN,sp|Q9HCH3|CPNE5_HUMAN,sp|Q96A23|CPNE4_HUMAN,tr|E7ENV7|E7ENV7_HUMAN" 9 1119.6077 2.84 7677 21183 2 1119.611748 560.8111 Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3 5.84 3858.6 - 1.57E+06 - - - 3.6334 - 1.585 0.398 - 169.8 1 2 0 0.0041 9 0 0 0 1.28E+07 4.50E+06 - - - 3.3118 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21188.21188.2 0.0403 18-Dec R.MALLATVLGR[166.11].F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1053.6244 2.13 7679 21188 2 1053.624694 527.8195 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.5 3859.2 - 396818 - - - 0.2733 - 2.417 0.412 - 635 1 2 0 0.0003 10 0 0 0 6.44E+07 3.02E+07 - - - 4.5473 0.9921 230117_WJC_METTL3_WT_vs_EV_F01.21190.21190.2 2.47E-06 13/26 K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 14.96 7681 21190 2 1613.793293 807.9078 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3859.4 - 1.08E+06 - - - -4.8352 - 2.136 0.479 - 308.8 1 2 0 -0.0078 14 0 0 0 1.82E+09 1.22E+08 - - - 4.481 1 230117_WJC_METTL3_WT_vs_EV_F01.21191.21191.2 2.91E-06 13/22 K.ITAEEMYDIFGK[136.11].Y sp|Q9Y3B4|SF3B6_HUMAN 1 1423.6785 1.99 7682 21191 2 1423.678646 712.8465 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.14 3859.6 - 616543 - - - 0.125 - 2.633 0.623 - 678.5 1 2 0 0.0002 12 0 0 0 1.72E+07 8.63E+06 - - - 6.1897 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21194.21194.2 0.00981 18-Oct R.SDLVLLYELK.Q sp|Q9NPF5|DMAP1_HUMAN 1 1191.6751 1.2 7685 21194 2 1191.675997 596.8448 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.37 3859.9 - 580754 - - - 0.7603 - 2.28 0.4 - 218.4 1 2 0 0.0009 10 0 0 0 5.90E+07 4.92E+07 - - - 4.2956 1 230117_WJC_METTL3_WT_vs_EV_F01.21197.21197.2 5.10E-06 18-Nov R.TMYLLGYIPK.D "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1197.6468 0.99 7688 21197 2 1197.648411 599.8307 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 8.17 3860.3 - 463086 - - - 1.3719 - 2.012 0.532 - 437.4 1 2 0 0.0016 10 0 0 0 9.17E+06 9.26E+06 - - - 4.9213 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21200.21200.2 8.25E-05 26-Nov R.WEGPLSVSVFAATK.E sp|O43505|B4GA1_HUMAN 1 1490.7769 0.64 7691 21200 2 1490.779623 746.3957 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 6 3860.7 - 290901 - - - 1.8064 - 1.742 0.525 - 268.5 1 2 0 0.0027 14 0 0 0 5.06E+06 7.92E+06 - - - 4.3106 0.9923 230117_WJC_METTL3_WT_vs_EV_F01.21201.21201.3 0.0889 Sep-40 R.LILWYFEHQLK.H sp|Q03701|CEBPZ_HUMAN 1 1488.8129 0.84 7692 21201 3 1488.81318 497.2783 CCAAT\enhancer-binding protein zeta OS=Homo sapiens OX=9606 GN=CEBPZ PE=1 SV=3 6.75 3860.9 - 251883 - - - 0.1733 - 1.399 0.21 - 87.5 1 2 0 0.0003 11 0 0 0 5.96E+06 7.13E+06 - - - 1.8351 0.991 230117_WJC_METTL3_WT_vs_EV_F01.21202.21202.2 6.93E-05 20-Oct K.LWC[160.03]SLADYYIR[166.11].S sp|Q9HCS7|SYF1_HUMAN 1 1468.7048 -1 7693 21202 2 1468.698646 735.3597 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 5.83 3861 - 234574 - - - -4.2187 - 1.993 0.339 - 300.7 1 2 0 -0.0062 11 0 0 0 0.00E+00 0.00E+00 - - - 3.4086 1 230117_WJC_METTL3_WT_vs_EV_F01.21203.21203.2 1.42E-11 14/30 R.VIFLEDDDVAAVVDGR[166.11].L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1741.8762 -1 7694 21203 2 1741.868128 871.9454 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 3.71 3861.1 - 222733 - - - -4.6341 - 3.205 0.655 - 629.3 1 2 0 -0.0081 16 0 0 0 0.00E+00 0.00E+00 - - - 6.7398 1 230117_WJC_METTL3_WT_vs_EV_F01.21204.21204.2 1.06E-06 13/20 K.LWC[160.03]SLADYYIR.S sp|Q9HCS7|SYF1_HUMAN 1 1458.6966 -1 7695 21204 2 1458.690597 730.3556 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 5.83 3861.2 - 190198 - - - -4.0961 - 2.743 0.563 - 806.5 1 2 0 -0.006 11 0 0 0 0.00E+00 0.00E+00 - - - 5.9272 0.997 230117_WJC_METTL3_WT_vs_EV_F01.21212.21212.2 0.000174 20-Dec R.FDEISFVNFAR.G sp|Q08945|SSRP1_HUMAN 1 1343.651 0.61 7702 21212 2 1343.65801 672.8328 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3862 - 1.52E+06 - - - 5.2164 - 1.97 0.383 - 405.7 1 2 0 0.007 11 0 0 0 9.56E+06 1.56E+07 - - - 3.7019 0.9926 230117_WJC_METTL3_WT_vs_EV_F01.21218.21218.2 0.013 12-Jul K.YFLWVVK.F sp|P62993|GRB2_HUMAN 1 953.5375 5.85 7708 21218 2 953.536761 477.776 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 8.59 3862.4 - 962830 - - - -0.7488 - 1.332 0.186 - 150.7 1 2 0 -0.0007 7 0 0 0 7.82E+06 1.34E+06 - - - 1.3229 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.21219.21219.3 1.82E-06 Nov-52 K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 14.44 7709 21219 3 1613.800838 538.941 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3862.5 - 808981 - - - -0.1599 - 2.259 0.372 - 194 1 2 0 -0.0003 14 0 0 0 5.59E+08 3.87E+07 - - - 4.853 1 230117_WJC_METTL3_WT_vs_EV_F01.21221.21221.2 1.93E-07 14/26 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 4.33 7711 21221 2 1535.792156 768.9025 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3862.6 - 704070 - - - 1.0574 - 2.531 0.516 - 554.1 1 2 0 0.0016 14 0 0 0 9.99E+07 2.31E+07 - - - 5.182 0.9224 230117_WJC_METTL3_WT_vs_EV_F01.21224.21224.2 5.07 12-Jun K.YFLWVVK[136.11].F sp|P62993|GRB2_HUMAN 1 961.5517 -1 7714 21224 2 961.553019 481.7831 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 8.59 3862.8 - 369364 - - - 1.3977 - 0.905 0.053 - 109 1 2 0 0.0013 7 0 0 0 0.00E+00 0.00E+00 - - - -0.8843 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.21230.21230.2 0.105 14-Jul R.TLFGFLGK.L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 881.5011 1.51 7718 21230 2 881.501639 441.7578 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3863.4 - 6.56E+06 - - - 0.6228 - 1.22 0.355 - 144.3 1 2 0 0.0005 8 0 0 0 3.93E+07 2.60E+07 - - - 2.2626 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21231.21231.2 0.0935 14-Oct K.VALLDVFR.E "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 931.5491 2.85 7719 21231 2 931.549597 466.7818 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.81 3863.5 - 7.17E+06 - - - 0.5314 - 2.003 0.315 - 510.4 1 2 0 0.0005 8 0 0 0 1.05E+08 3.66E+07 - - - 3.4625 1 230117_WJC_METTL3_WT_vs_EV_F01.21232.21232.2 0.000181 14/22 K.TLGVDLVALATR[166.11].V "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1237.727 2.4 7720 21232 2 1237.728906 619.8708 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.5 3863.6 - 7.43E+06 - - - 1.5747 - 2.486 0.494 - 584.4 1 2 0 0.0019 12 0 0 0 4.75E+07 1.98E+07 - - - 5.0852 1 230117_WJC_METTL3_WT_vs_EV_F01.21233.21233.2 6.97E-05 13/20 R.PLEVFMC[160.03]SVLK.R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1321.6774 5.27 7721 21233 2 1321.675383 661.846 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.38 3863.6 - 6.68E+06 - - - -1.5382 - 2.321 0.547 - 525.6 1 1 0 -0.002 11 0 0 0 4.11E+07 7.78E+06 - - - 5.3583 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.21235.21235.2 0.0277 14-Jul R.TLFGFLGK[136.11].L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 889.5153 1.51 7723 21235 2 889.515509 445.7649 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3863.8 - 4.70E+06 - - - 0.2462 - 1.027 0.372 - 149.1 1 2 0 0.0002 8 0 0 0 3.93E+07 2.60E+07 - - - 1.8689 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.21237.21237.2 0.268 14-Aug K.VALLDVFR[166.11].E "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 941.5574 2.85 7725 21237 2 941.557969 471.786 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.81 3864 - 3.21E+06 - - - 0.6341 - 1.845 0.159 - 313.4 1 2 0 0.0006 8 0 0 0 1.05E+08 3.66E+07 - - - 2.0624 1 230117_WJC_METTL3_WT_vs_EV_F01.21238.21238.2 8.22E-06 13/20 R.PLEVFMC[160.03]SVLK[136.11].R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1329.6916 5.21 7726 21238 2 1329.690956 665.8531 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.38 3864.1 - 2.80E+06 - - - -0.4964 - 2.617 0.559 - 509.1 1 1 0 -0.0007 11 0 0 0 4.06E+07 7.78E+06 - - - 5.7721 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21239.21239.2 4.05E-05 14/20 K.LEDVLPLAFTR.L "sp|Q5SSJ5|HP1B3_HUMAN,tr|B0QZK4|B0QZK4_HUMAN,tr|Q5SWC8|Q5SWC8_HUMAN" 3 1272.7078 0.66 7727 21239 2 1272.709361 637.3612 Heterochromatin protein 1-binding protein 3 OS=Homo sapiens OX=9606 GN=HP1BP3 PE=1 SV=1 4.37 3864.2 - 2.73E+06 - - - 1.2359 - 2.363 0.351 - 725.2 1 2 0 0.0016 11 0 0 0 7.21E+06 1.09E+07 - - - 3.9593 1 230117_WJC_METTL3_WT_vs_EV_F01.21240.21240.2 1.86E-05 20-Nov R.DSLIFLVDASK.A sp|P12956|XRCC6_HUMAN 1 1206.6496 0.92 7728 21240 2 1206.65111 604.3321 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.21 3864.3 - 2.55E+06 - - - 1.2481 - 2.318 0.459 - 365.6 1 2 0 0.0015 11 0 0 0 3.79E+07 4.12E+07 - - - 4.705 1 230117_WJC_METTL3_WT_vs_EV_F01.21244.21244.3 1.94E-09 17/52 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 4.66 7732 21244 3 1535.793264 512.9375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3864.8 - 1.52E+06 - - - 1.7789 - 2.987 0.575 - 439.3 1 2 0 0.0027 14 0 0 0 2.88E+07 6.17E+06 - - - 7.858 1 230117_WJC_METTL3_WT_vs_EV_F01.21246.21246.2 2.14E-10 19/28 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 3.27 7734 21246 2 1700.900614 851.4565 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3865.1 - 1.43E+06 - - - 1.2417 - 3.6 0.647 - 1043 1 2 0 0.0021 15 0 0 0 5.07E+08 1.55E+08 - - - 6.9683 0.9911 230117_WJC_METTL3_WT_vs_EV_F01.21247.21247.2 0.206 24-Dec R.LIGEMNSLFDEVR.Q "sp|Q9P2W9|STX18_HUMAN,tr|D6RF48|D6RF48_HUMAN" 2 1521.7497 -1 7735 21247 2 1521.753704 761.8821 Syntaxin-18 OS=Homo sapiens OX=9606 GN=STX18 PE=1 SV=1 4.14 3865.2 - 1.40E+06 - - - 2.6121 - 1.105 0.207 - 205.4 1 2 0 0.004 13 0 0 0 0.00E+00 0.00E+00 - - - 0.8249 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21249.21249.2 8.85E-05 26-Dec K.TFAPEEISAMVLTK[136.11].M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1543.8047 4.33 7737 21249 2 1543.806927 772.9096 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3865.5 - 1.24E+06 - - - 1.4218 - 2.122 0.464 - 360.2 1 2 0 0.0022 14 0 0 0 9.99E+07 2.31E+07 - - - 4.3554 1 230117_WJC_METTL3_WT_vs_EV_F01.21253.21253.2 1.27E-06 18/28 R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 3.27 7740 21253 2 1710.903023 856.4607 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3866.1 - 7.87E+06 - - - -2.1912 - 3.533 0.576 - 899.2 1 2 0 -0.0037 15 0 0 0 5.07E+08 1.55E+08 - - - 6.3972 1 230117_WJC_METTL3_WT_vs_EV_F01.21255.21255.3 3.12E-09 20/56 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 3.94 7742 21255 3 1700.898592 567.9734 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3866.2 - 6.81E+06 - - - 0.0529 - 3.464 0.617 - 672.1 1 2 0 0.0001 15 0 0 0 1.45E+08 3.67E+07 - - - 8.6609 1 230117_WJC_METTL3_WT_vs_EV_F01.21257.21257.2 1.38E-05 14/26 R.VLLATLSIPITPER.T sp|Q14152|EIF3A_HUMAN 1 1521.913 1.03 7744 21257 2 1521.912313 761.9638 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3866.4 - 4.25E+06 - - - -0.4711 - 2.903 0.498 - 476.7 1 2 0 -0.0007 14 0 0 0 5.80E+07 5.64E+07 - - - 5.3934 1 230117_WJC_METTL3_WT_vs_EV_F01.21260.21260.2 1.08E-08 19/28 K.VSALDLAVLDQVEAR.L "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 6 1597.8675 2.39 7747 21260 2 1597.869449 799.941 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.03 3866.8 - 2.47E+06 - - - 1.1972 - 3.703 0.487 - 1531.1 1 2 0 0.0019 15 0 0 0 6.11E+06 2.55E+06 - - - 5.856 1 230117_WJC_METTL3_WT_vs_EV_F01.21262.21262.2 1.19E-08 26-Dec K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 14.95 7749 21262 2 1621.812992 811.9149 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3867 - 2.21E+06 - - - -1.4206 - 2.353 0.626 - 346.6 1 2 0 -0.0023 14 0 0 0 1.82E+09 1.22E+08 - - - 5.8112 1 230117_WJC_METTL3_WT_vs_EV_F01.21263.21263.2 6.78E-07 15/26 K.LFIYNPTTGEFLGR.T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1626.8406 1.66 7750 21263 2 1626.837912 814.4276 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3867.1 - 2.05E+06 - - - -1.648 - 2.639 0.501 - 687.9 1 2 0 -0.0027 14 0 0 0 3.86E+07 2.32E+07 - - - 5.1757 1 230117_WJC_METTL3_WT_vs_EV_F01.21265.21265.2 3.11E-07 13/22 R.LEGLTDEINFLR.Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1418.7405 1.47 7752 21265 2 1418.740311 710.3775 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3867.4 - 1.58E+06 - - - -0.1649 - 2.816 0.553 - 733.2 1 2 0 -0.0002 12 0 0 0 2.44E+07 1.66E+07 - - - 5.8495 1 230117_WJC_METTL3_WT_vs_EV_F01.21266.21266.2 1.27E-05 13/22 K.VPDGMVGFIIGR[166.11].G "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 3 1269.6779 8.18 7753 21266 2 1269.677059 635.8462 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 5.81 3867.5 - 1.18E+06 - - - -0.6608 - 2.301 0.465 - 651.5 1 2 0 -0.0008 12 0 0 0 3.09E+07 3.77E+06 - - - 4.6679 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.21267.21267.2 2.00E-05 16-Aug K.YPENFFLLR.G "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|C9J9S3|C9J9S3_HUMAN,tr|E7ETD8|E7ETD8_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 12 1197.6182 7.15 7754 21267 2 1197.617323 599.8164 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 6 3867.6 - 970534 - - - -0.7699 - 1.89 0.464 - 237 1 2 0 -0.0009 9 0 0 0 4.52E+06 6.32E+05 - - - 4.3095 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.21268.21268.2 0.00122 14-Aug R.FFFNLGVK[136.11].A sp|Q01804|OTUD4_HUMAN 1 978.5418 0.94 7755 21268 2 978.542434 490.2782 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 8.75 3867.8 - 896645 - - - 0.608 - 1.33 0.393 - 135.6 1 2 0 0.0006 8 0 0 0 3.78E+06 4.00E+06 - - - 2.8036 1 230117_WJC_METTL3_WT_vs_EV_F01.21269.21269.2 2.00E-05 15/28 K.LLDTVDDMLANDIAR.L "sp|Q9H4M9|EHD1_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 3 1673.8294 -1 7756 21269 2 1673.824953 837.922 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 3.77 3867.9 - 872588 - - - -2.6783 - 2.893 0.597 - 608.2 1 2 0 -0.0045 15 0 0 0 0.00E+00 0.00E+00 - - - 6.0607 1 230117_WJC_METTL3_WT_vs_EV_F01.21276.21276.2 3.50E-08 14/22 R.LEGLTDEINFLR[166.11].Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1428.7488 1.64 7762 21276 2 1428.749137 715.3817 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3868.5 - 4.10E+06 - - - 0.2254 - 2.804 0.526 - 908.9 1 2 0 0.0003 12 0 0 0 2.44E+07 1.48E+07 - - - 5.6388 1 230117_WJC_METTL3_WT_vs_EV_F01.21277.21277.2 3.77E-06 26-Dec K.LFIYNPTTGEFLGR[166.11].T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1636.8489 1.66 7763 21277 2 1636.851618 819.4317 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3868.5 - 3.98E+06 - - - 1.6831 - 2.02 0.537 - 406.1 1 2 0 0.0028 14 0 0 0 3.86E+07 2.32E+07 - - - 4.7708 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21280.21280.3 0.00081 Aug-52 R.VLLATLSIPITPER.T sp|Q14152|EIF3A_HUMAN 1 1521.913 1.03 7766 21280 3 1521.913941 508.3116 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3868.7 - 2.56E+06 - - - 0.5986 - 1.845 0.379 - 86 1 2 0 0.0009 14 0 0 0 5.22E+06 5.04E+06 - - - 4.3929 1 230117_WJC_METTL3_WT_vs_EV_F01.21281.21281.2 8.56E-06 18-Nov R.WYEWLDPSIK.K sp|Q99459|CDC5L_HUMAN 1 1335.6499 1.62 7767 21281 2 1335.649611 668.8322 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3868.8 - 2.53E+06 - - - -0.2456 - 1.978 0.51 - 420.7 1 2 0 -0.0003 10 0 0 0 1.73E+07 1.06E+07 - - - 4.7117 0.8684 230117_WJC_METTL3_WT_vs_EV_F01.21283.21283.2 0.000133 22-Sep R.DYLHLPPEIVPA.T "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1362.7184 - 7769 21283 2 1362.715949 682.3665 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.35 3868.9 - 1.57E+06 - - - -1.7641 - 1.717 0.404 - 162.6 1 1 0 -0.0024 12 0 0 0 - - - - - 3.4465 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.21286.21286.2 0.00468 14-Aug R.FFFNLGVK.A sp|Q01804|OTUD4_HUMAN 1 970.5276 0.96 7772 21286 2 970.527338 486.2711 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 8.75 3869.3 - 1.28E+06 - - - -0.3101 - 1.387 0.458 - 141.8 1 2 0 -0.0003 8 0 0 0 3.86E+06 4.00E+06 - - - 3.4103 1 230117_WJC_METTL3_WT_vs_EV_F01.21287.21287.2 1.94E-06 14/26 R.VFGAPEVLENLEVK[136.11].S sp|Q8TEM1|PO210_HUMAN 1 1550.8436 2.51 7773 21287 2 1550.845139 776.4291 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.25 3869.4 - 1.04E+06 - - - 1.0182 - 2.57 0.504 - 486.5 1 2 0 0.0016 14 0 0 0 1.05E+07 4.18E+06 - - - 5.1317 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21288.21288.3 3.19E-05 Oct-36 K.YRPLFDYFLK.C "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 1360.718 1.15 7774 21288 3 1360.716351 454.5799 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.5 3869.6 - 855184 - - - -1.1817 - 2.055 0.437 - 136 1 2 0 -0.0016 10 0 0 0 3.24E+06 2.81E+06 - - - 5.5152 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21289.21289.2 0.00915 20-Oct K.IALGIPLPEIK.N "sp|P31327|CPSM_HUMAN,tr|A0A669KBF2|A0A669KBF2_HUMAN" 2 1162.7325 2.21 7775 21289 2 1162.733796 582.3735 "Carbamoyl-phosphate synthase [ammonia], mitochondrial OS=Homo sapiens OX=9606 GN=CPS1 PE=1 SV=2" 6 3869.7 - 823970 - - - 1.0751 - 2.087 0.291 - 253 1 2 0 0.0013 11 0 0 0 2.08E+06 9.44E+05 - - - 3.1803 1 230117_WJC_METTL3_WT_vs_EV_F01.21291.21291.2 3.20E-07 13/26 K.MLGLTVSLIQDAGR[166.11].T "sp|Q9Y3E5|PTH2_HUMAN,tr|J3KQ48|J3KQ48_HUMAN" 2 1482.8104 -1 7777 21291 2 1482.811616 742.4125 "Peptidyl-tRNA hydrolase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PTRH2 PE=1 SV=1" 5.59 3870 - 397480 - - - 0.841 - 2.362 0.529 - 553.7 1 2 0 0.0012 14 0 0 0 0.00E+00 0.00E+00 - - - 5.1047 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.21295.21295.3 6.00E-05 15/56 R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 3.94 7780 21295 3 1710.906428 571.3095 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3870.4 - 5.52E+06 - - - -0.2011 - 2.744 0.466 - 380.9 1 2 0 -0.0003 15 0 0 0 1.44E+08 3.66E+07 - - - 6.3693 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21296.21296.2 5.70E-06 13/20 R.GVTFLFPIQAK.T sp|Q9NR30|DDX21_HUMAN 1 1219.6965 0.84 7781 21296 2 1219.696439 610.8555 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3870.4 - 3.18E+06 - - - -0.0459 - 2.426 0.365 - 754.7 1 2 0 -0.0001 11 0 0 0 1.03E+08 1.22E+08 - - - 4.1344 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.21305.21305.2 0.00186 14-Sep R.FPLFGGWK[136.11].T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 958.5156 1.47 7790 21305 2 958.514705 480.2651 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3871.5 - 424093 - - - -0.9588 - 1.65 0.405 - 302.5 1 2 0 -0.0009 8 0 0 0 1.92E+07 1.31E+07 - - - 3.5424 1 230117_WJC_METTL3_WT_vs_EV_F01.21306.21306.2 4.06E-07 14/24 R.APLPDLYPFGTMR.G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1476.7435 1.74 7791 21306 2 1476.741134 739.379 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3871.7 - 399956 - - - -1.6171 - 2.332 0.544 - 577.6 1 2 0 -0.0024 13 0 0 0 1.65E+07 9.52E+06 - - - 5.2314 1 230117_WJC_METTL3_WT_vs_EV_F01.21307.21307.2 0.000639 18-Oct K.YLMIEEYLTK.E sp|O95817|BAG3_HUMAN 1 1301.6577 6.68 7792 21307 2 1301.650802 651.8361 BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3 4.53 3871.8 - 297491 - - - -5.3194 - 2.008 0.519 - 316 1 2 0 -0.0069 10 0 0 0 6.80E+06 1.02E+06 - - - 4.8181 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.21311.21311.2 0.00109 20-Nov R.GVTFLFPIQAK[136.11].T sp|Q9NR30|DDX21_HUMAN 1 1227.7107 0.97 7795 21311 2 1227.710974 614.8626 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3872.3 - 1.20E+07 - - - 0.2273 - 2.115 0.315 - 394.2 1 2 0 0.0003 11 0 0 0 9.98E+07 1.03E+08 - - - 3.3939 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21313.21313.2 0.0148 13/20 K.SGAYLIPLLER[166.11].L "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1240.7055 1.26 7796 21313 2 1240.707693 621.36 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.72 3872.6 - 7.46E+06 - - - 1.7732 - 2.336 0.341 - 653.3 1 2 0 0.0022 11 0 0 0 3.34E+08 2.66E+08 - - - 3.8542 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.21316.21316.2 0.00132 18-Oct K.FSLFAGGMLR.V sp|Q9BVK6|TMED9_HUMAN 1 1097.5692 1.26 7799 21316 2 1097.568581 549.7919 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 9.75 3872.7 - 1.95E+06 - - - -0.5512 - 2.157 0.431 - 365.8 1 2 0 -0.0006 10 0 0 0 2.22E+07 1.77E+07 - - - 4.3699 1 230117_WJC_METTL3_WT_vs_EV_F01.21317.21317.3 1.80E-08 14/52 K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 14.44 7800 21317 3 1621.81299 541.6124 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3872.8 - 1.39E+06 - - - -1.4219 - 2.519 0.611 - 278.7 1 2 0 -0.0023 14 0 0 0 5.59E+08 3.87E+07 - - - 7.8066 1 230117_WJC_METTL3_WT_vs_EV_F01.21319.21319.2 0.0244 15/26 R.IADQFLGAMYTLPR.Q "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN,tr|R4GMP9|R4GMP9_HUMAN" 3 1594.8177 999 7802 21319 2 1594.823757 798.4162 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 5.84 3873 - 773000 - - - 3.7672 - 3.351 0.485 - 792.1 1 2 0 0.006 14 0 0 0 2.82E+06 0.00E+00 - - - 5.6559 1 230117_WJC_METTL3_WT_vs_EV_F01.21321.21321.2 7.33E-05 24-Dec R.APLPDLYPFGTMR[166.11].G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1486.7518 1.83 7804 21321 2 1486.755005 744.3832 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3873.3 - 590626 - - - 2.1611 - 2.177 0.519 - 476.1 1 2 0 0.0032 13 0 0 0 1.57E+07 8.58E+06 - - - 4.87 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21329.21329.2 0.000766 18-Oct K.FEELNMDLFR.S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1312.6122 3.84 7810 21329 2 1312.612529 657.3134 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.14 3874 - 2.64E+06 - - - 0.2712 - 2.195 0.431 - 378.7 1 2 0 0.0004 10 0 0 0 7.97E+07 2.08E+07 - - - 4.4187 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.21331.21331.2 0.0374 14-Jul K.FYSFLVLK.K "sp|Q9H4I0|RD21L_HUMAN,sp|O60216|RAD21_HUMAN,tr|A0A804HJ87|A0A804HJ87_HUMAN,tr|E5RI01|E5RI01_HUMAN,tr|E5RG18|E5RG18_HUMAN,tr|E5RFZ5|E5RFZ5_HUMAN" 6 1015.5743 2.95 7812 21331 2 1015.574642 508.7944 Double-strand-break repair protein rad21-like protein 1 OS=Homo sapiens OX=9606 GN=RAD21L1 PE=2 SV=3 8.59 3874.1 - 1.17E+06 - - - 0.3811 - 1.293 0.267 - 110.1 1 2 0 0.0004 8 0 0 0 4.75E+07 1.61E+07 - - - 1.7879 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.21332.21332.2 0.00498 16-Sep R.IIFVDEVFK.L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1108.6168 4.72 7813 21332 2 1108.621979 555.3157 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 4.37 3874.2 - 1.12E+06 - - - 4.6283 - 1.619 0.365 - 170.2 1 2 0 0.0051 9 0 0 0 5.82E+07 1.23E+07 - - - 3.1292 0.9417 230117_WJC_METTL3_WT_vs_EV_F01.21333.21333.2 0.000111 12-Sep Y.SSFLFWR.M sp|Q13015|AF1Q_HUMAN 1 941.4759 5.75 7814 21333 2 941.474814 471.7452 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 9.47 3874.3 - 722603 - - - -1.1939 - 1.747 0.509 - 330.8 1 1 0 -0.0011 7 0 0 0 7.46E+06 1.30E+06 - - - 4.5679 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21334.21334.2 0.00228 18-Oct K.FEELNMDLFR[166.11].S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1322.6204 3.78 7815 21334 2 1322.621802 662.3175 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.14 3874.4 - 562077 - - - 1.0275 - 2.115 0.352 - 327.9 1 2 0 0.0014 10 0 0 0 7.97E+07 2.11E+07 - - - 3.7313 0.9808 230117_WJC_METTL3_WT_vs_EV_F01.21335.21335.2 0.237 20-Aug R.SGIVEYLSLVK[136.11].G "sp|P49642|PRI1_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN,tr|F8VNY2|F8VNY2_HUMAN" 3 1214.7002 1.71 7816 21335 2 1214.699007 608.3574 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 5.72 3874.5 - 399447 - - - -0.9739 - 1.315 0.124 - 111.5 1 2 0 -0.0012 11 0 0 0 1.23E+07 7.19E+06 - - - 0.6973 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.21337.21337.2 0.000425 20-Nov R.SGIVEYLSLVK.G "sp|P49642|PRI1_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN,tr|F8VNY2|F8VNY2_HUMAN" 3 1206.686 1.71 7818 21337 2 1206.691425 604.3503 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 5.72 3874.8 - 347702 - - - 4.5041 - 2.113 0.461 - 272.7 1 2 0 0.0054 11 0 0 0 1.23E+07 7.19E+06 - - - 4.4681 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21338.21338.2 0.00491 20-Oct K.LSDLDYMQFIR[166.11].L sp|P82933|RT09_HUMAN 1 1409.6889 1.02 7819 21338 2 1409.691388 705.8517 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.21 3874.9 - 251824 - - - 1.7954 - 2.489 0.385 - 567.9 1 2 0 0.0025 11 0 0 0 2.08E+07 2.05E+07 - - - 4.3507 1 230117_WJC_METTL3_WT_vs_EV_F01.21345.21345.2 9.29E-07 16/26 R.VLLATLSIPITPER[166.11].T sp|Q14152|EIF3A_HUMAN 1 1531.9213 1.05 7823 21345 2 1531.920015 766.9679 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3875.6 - 1.52E+06 - - - -0.8388 - 3.102 0.501 - 807.5 1 2 0 -0.0013 14 0 0 0 4.08E+07 3.88E+07 - - - 5.5818 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.21347.21347.2 0.0484 18-Aug K.FSLFAGGMLR[166.11].V sp|Q9BVK6|TMED9_HUMAN 1 1107.5775 1.27 7824 21347 2 1107.578131 554.796 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 9.75 3875.8 - 460095 - - - 0.6094 - 1.446 0.302 - 143.8 1 2 0 0.0007 10 0 0 0 2.22E+07 1.75E+07 - - - 2.3008 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21348.21348.2 0.000574 14-Aug R.GFVFITFK[136.11].E "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 965.5466 0.77 7825 21348 2 965.546959 483.7806 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3875.9 - 549797 - - - 0.3822 - 1.612 0.445 - 273.6 1 2 0 0.0004 8 0 0 0 3.45E+07 4.49E+07 - - - 3.7677 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21349.21349.2 0.000249 16-Jul R.IIFVDEVFK[136.11].L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1116.631 4.72 7826 21349 2 1116.631741 559.3228 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 4.37 3876 - 0 - - - 0.6206 - 1.503 0.478 - 105.3 1 2 0 0.0007 9 0 0 0 5.82E+07 1.23E+07 - - - 3.7501 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21350.21350.3 0.0233 13/44 R.LLALLDALASHK[136.11].A "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 1271.7693 2.06 7827 21350 3 1271.768208 424.9304 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6.74 3876 - 0 - - - -0.8374 - 2.306 0.376 - 281.4 1 2 0 -0.0011 12 0 0 0 9.31E+06 4.52E+06 - - - 5.0477 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.21352.21352.2 0.00208 20-Oct K.NVPGLAILLSK.D sp|Q9BUL9|RPP25_HUMAN 1 1123.6965 1.14 7829 21352 2 1123.698249 562.8555 Ribonuclease P protein subunit p25 OS=Homo sapiens OX=9606 GN=RPP25 PE=1 SV=1 8.75 3876.2 - 0 - - - 1.5609 - 1.578 0.262 - 229.4 1 2 0 0.0018 11 0 0 0 1.38E+07 1.21E+07 - - - 2.2096 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.21356.21356.2 0.0356 14-Aug R.WLLDFASK.R "sp|P33121|ACSL1_HUMAN,tr|B7Z3Z9|B7Z3Z9_HUMAN,tr|E7EPM6|E7EPM6_HUMAN" 3 978.5175 1.97 7833 21356 2 978.518079 490.266 Long-chain-fatty-acid--CoA ligase 1 OS=Homo sapiens OX=9606 GN=ACSL1 PE=1 SV=1 5.84 3876.7 - 175526 - - - 0.6244 - 1.55 0.213 - 184.2 1 2 0 0.0006 8 0 0 0 2.76E+06 1.41E+06 - - - 1.9358 1 230117_WJC_METTL3_WT_vs_EV_F01.21362.21362.2 0.00294 13/20 K.LSDLDYMQFIR.L sp|P82933|RT09_HUMAN 1 1399.6806 1.02 7837 21362 2 1399.680125 700.8476 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.21 3877.5 - 3.17E+06 - - - -0.3301 - 3.033 0.422 - 1058.4 1 2 0 -0.0005 11 0 0 0 2.08E+07 2.05E+07 - - - 5.1593 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.21363.21363.2 0.000374 14-Aug R.GFVFITFK.E "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 957.5324 0.77 7838 21363 2 957.532132 479.7735 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3877.5 - 4.19E+06 - - - -0.2694 - 1.574 0.44 - 255 1 2 0 -0.0003 8 0 0 0 3.45E+07 4.49E+07 - - - 3.6589 1 230117_WJC_METTL3_WT_vs_EV_F01.21364.21364.2 5.10E-06 14/24 R.LLSFSPEEFPTLK.A sp|Q5JSZ5|PRC2B_HUMAN 1 1506.797 1.41 7839 21364 2 1506.800875 754.4058 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3877.7 - 2.27E+06 - - - 2.5737 - 2.299 0.523 - 629.8 1 2 0 0.0039 13 0 0 0 9.82E+07 6.95E+07 - - - 5.0392 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.21365.21365.2 0.0523 16-Jul K.TTPLLSFLK[136.11].N sp|Q9BZI7|REN3B_HUMAN 1 1026.6205 0.9 7840 21365 2 1026.621829 514.3175 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 8.41 3877.8 - 2.22E+06 - - - 1.3111 - 1.468 0.276 - 163.1 1 2 0 0.0013 9 0 0 0 3.61E+07 3.99E+07 - - - 2.1898 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.21367.21367.3 0.0314 Nov-44 R.LLALLDALASHK.A "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 1263.7551 2.06 7842 21367 3 1263.754091 422.259 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6.74 3878 - 2.01E+06 - - - -0.777 - 2.626 0.278 - 195.9 1 2 0 -0.001 12 0 0 0 9.31E+06 4.52E+06 - - - 4.3153 1 230117_WJC_METTL3_WT_vs_EV_F01.21368.21368.2 0.000462 22-Dec K.LADFALLC[160.03]LDGK.R "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 1334.6904 999 7843 21368 2 1334.688125 668.3525 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 4.21 3878.2 - 1.62E+06 - - - -1.7225 - 3.053 0.463 - 613.8 1 2 0 -0.0023 12 0 0 0 7.41E+06 0.00E+00 - - - 5.3967 1 230117_WJC_METTL3_WT_vs_EV_F01.21369.21369.2 5.00E-09 17/26 R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 25.65 7844 21369 2 1581.809905 791.9109 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3878.3 - 1.55E+06 - - - 1.6823 - 3.234 0.63 - 760.9 1 2 0 0.0027 14 0 0 0 3.88E+07 1.51E+06 - - - 6.6387 1 230117_WJC_METTL3_WT_vs_EV_F01.21370.21370.2 2.10E-05 13/24 R.ELPTAFDYVEFTR[166.11].S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1596.7699 1.05 7845 21370 2 1596.776476 799.3922 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.14 3878.4 - 1.25E+06 - - - 4.0908 - 2.629 0.493 - 787.4 1 2 0 0.0065 13 0 0 0 2.10E+07 2.00E+07 - - - 5.1611 0.999 230117_WJC_METTL3_WT_vs_EV_F01.21372.21372.2 0.00295 20-Oct K.TLDVFNITIAR[166.11].Q sp|Q96RL7|VP13A_HUMAN 1 1271.7113 0.77 7847 21372 2 1271.710767 636.8629 Vacuolar protein sorting-associated protein 13A OS=Homo sapiens OX=9606 GN=VPS13A PE=1 SV=2 5.5 3878.7 - 799176 - - - -0.4246 - 1.797 0.337 - 210.7 1 2 0 -0.0005 11 0 0 0 3.78E+06 4.92E+06 - - - 3.1155 0.9907 230117_WJC_METTL3_WT_vs_EV_F01.21376.21376.2 0.0382 20-Jul R.VWIPDPDEVWR[166.11].S sp|Q9ULV0|MYO5B_HUMAN 1 1420.7015 -1 7851 21376 2 1420.698114 711.358 Unconventional myosin-Vb OS=Homo sapiens OX=9606 GN=MYO5B PE=1 SV=3 4.03 3879.2 - 612418 - - - -2.3629 - 1.475 0.261 - 157.9 1 2 0 -0.0034 11 0 0 0 0.00E+00 0.00E+00 - - - 2.0191 0.9969 230117_WJC_METTL3_WT_vs_EV_F01.21377.21377.2 0.0124 Jun-36 R.LAESLLALSQQEELADLPK.D sp|Q9BVJ6|UT14A_HUMAN 1 2067.11 -1 7852 21377 2 2067.110053 1034.5623 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4 3879.4 - 567575 - - - 0.0489 - 1.477 0.242 - 22.8 2 2 0 0.0001 19 0 0 0 0.00E+00 0.00E+00 - - - 1.6528 0.9559 230117_WJC_METTL3_WT_vs_EV_F01.21378.21378.3 0.165 Jul-40 K.SGAYLIPLLER.L "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1230.6972 1.09 7853 21378 3 1230.697589 411.2397 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.72 3879.5 - 375516 - - - 0.2974 - 1.449 0.121 - 39.3 4 2 0 0.0004 11 0 0 0 1.20E+06 1.11E+06 - - - 0.6639 0.9582 230117_WJC_METTL3_WT_vs_EV_F01.21381.21381.2 0.35 22-Mar R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 7855 21381 2 1603.765275 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3879.8 - 1.68E+07 - - - 0.8324 - 0.74 0.177 - 29.1 1 2 0 0.0013 12 0 0 0 3.61E+09 0.00E+00 - - - -0.4444 1 230117_WJC_METTL3_WT_vs_EV_F01.21385.21385.2 0.000189 24-Sep R.LLSFSPEEFPTLK[136.11].A sp|Q5JSZ5|PRC2B_HUMAN 1 1514.8112 1.41 7858 21385 2 1514.815247 758.4129 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3880.2 - 1.69E+07 - - - 2.6736 - 2.101 0.495 - 216.2 1 2 0 0.004 13 0 0 0 9.82E+07 6.95E+07 - - - 4.6012 1 230117_WJC_METTL3_WT_vs_EV_F01.21388.21388.3 3.15E-05 14/52 R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 13.02 7861 21388 3 1581.808989 528.2764 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3880.5 - 5.48E+06 - - - 1.1032 - 2.717 0.503 - 418.3 1 2 0 0.0017 14 0 0 0 1.05E+07 8.09E+05 - - - 6.8037 1 230117_WJC_METTL3_WT_vs_EV_F01.21391.21391.2 3.17E-06 16/26 R.ILSVQGTEPLVLFK.E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1542.9021 1.28 7864 21391 2 1542.903933 772.4583 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3880.8 - 4.02E+06 - - - 1.1679 - 2.654 0.56 - 781.9 1 2 0 0.0018 14 0 0 0 2.26E+07 1.76E+07 - - - 5.626 1 230117_WJC_METTL3_WT_vs_EV_F01.21392.21392.2 5.86E-06 22-Oct K.LTAYAMTIPFVR.Q "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1381.7428 1.4 7865 21392 2 1381.743369 691.8787 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 3880.9 - 3.59E+06 - - - 0.4169 - 2.092 0.503 - 443.7 1 2 0 0.0006 12 0 0 0 8.75E+06 6.25E+06 - - - 4.6981 1 230117_WJC_METTL3_WT_vs_EV_F01.21394.21394.2 6.81E-07 16/26 R.ILSVQGTEPLVLFK[136.11].E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1550.9163 1.28 7867 21394 2 1550.918327 776.4654 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3881.1 - 3.34E+06 - - - 1.287 - 2.807 0.569 - 851.6 1 2 0 0.002 14 0 0 0 2.26E+07 1.76E+07 - - - 5.8331 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21397.21397.2 8.50E-05 22-Oct K.LTAYAMTIPFVR[166.11].Q "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1391.7511 1.4 7870 21397 2 1391.75064 696.8828 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 3881.4 - 2.58E+06 - - - -0.3039 - 2.081 0.455 - 443.1 1 2 0 -0.0004 12 0 0 0 8.75E+06 6.25E+06 - - - 4.3297 1 230117_WJC_METTL3_WT_vs_EV_F01.21398.21398.2 8.47E-06 13/24 R.ELYAFFGDSLATR.F sp|Q9Y6J9|TAF6L_HUMAN 1 1488.7249 1.24 7871 21398 2 1488.721578 745.3697 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4.37 3881.5 - 2.40E+06 - - - -2.2281 - 2.415 0.571 - 566.2 1 2 0 -0.0033 13 0 0 0 8.68E+06 6.99E+06 - - - 5.5203 0.999 230117_WJC_METTL3_WT_vs_EV_F01.21401.21401.2 0.134 20-Sep K.NVPGLAILLSK[136.11].D sp|Q9BUL9|RPP25_HUMAN 1 1131.7107 1.14 7874 21401 2 1131.711239 566.8626 Ribonuclease P protein subunit p25 OS=Homo sapiens OX=9606 GN=RPP25 PE=1 SV=1 8.75 3881.9 - 2.01E+06 - - - 0.4807 - 1.601 0.305 - 176.5 1 2 0 0.0005 11 0 0 0 1.38E+07 1.21E+07 - - - 2.5667 1 230117_WJC_METTL3_WT_vs_EV_F01.21404.21404.3 5.73E-06 13/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 7876 21404 3 1603.766259 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3882.3 - 2.87E+07 - - - 1.446 - 2.44 0.559 - 248.6 1 2 0 0.0023 12 0 0 0 3.12E+08 0.00E+00 - - - 7.2441 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.21405.21405.2 0.0013 18-Aug R.YVLGMQELFR[166.11].G "sp|Q96J01|THOC3_HUMAN,tr|D6RGZ2|D6RGZ2_HUMAN" 2 1264.6513 1.03 7877 21405 2 1264.649748 633.333 THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1 6 3882.4 - 1.46E+06 - - - -1.266 - 1.389 0.322 - 203 1 2 0 -0.0016 10 0 0 0 2.70E+07 2.62E+07 - - - 2.336 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.21408.21408.2 0.000829 16-Aug K.TTPLLSFLK.N sp|Q9BZI7|REN3B_HUMAN 1 1018.6063 0.9 7880 21408 2 1018.609438 510.3104 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 8.41 3882.6 - 4.16E+06 - - - 3.0974 - 1.546 0.378 - 283.4 1 2 0 0.0032 9 0 0 0 3.58E+07 3.99E+07 - - - 3.0923 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.21410.21410.2 0.00058 18-Nov R.LLEVYDQLFK.S "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1266.686 1.75 7882 21410 2 1266.690905 634.3503 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3882.7 - 2.83E+06 - - - 3.8802 - 2.181 0.443 - 420.4 1 2 0 0.0049 10 0 0 0 1.75E+07 1.00E+07 - - - 4.4881 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21412.21412.2 8.41E-05 16-Aug K.AFVPAILFK[136.11].D sp|Q9HAU5|RENT2_HUMAN 1 1012.6201 1 7884 21412 2 1012.6213 507.3173 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3882.8 - 2.20E+06 - - - 1.1959 - 1.689 0.473 - 225.4 1 2 0 0.0012 9 0 0 0 1.30E+07 1.30E+07 - - - 4.0506 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.21414.21414.2 0.00147 16-Jul K.AFVPAILFK.D sp|Q9HAU5|RENT2_HUMAN 1 1004.6059 1 7886 21414 2 1004.606595 503.3102 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3883 - 1.85E+06 - - - 0.7028 - 1.46 0.403 - 160.3 1 2 0 0.0007 9 0 0 0 1.30E+07 1.30E+07 - - - 3.1122 1 230117_WJC_METTL3_WT_vs_EV_F01.21416.21416.2 0.0274 14/26 K.TGAAGAEALSLLLK.R "sp|Q9P2N6|KANL3_HUMAN,tr|C9J5A4|C9J5A4_HUMAN,tr|A0A590UJ53|A0A590UJ53_HUMAN" 3 1313.7555 3.82 7888 21416 2 1313.756539 657.885 KAT8 regulatory NSL complex subunit 3 OS=Homo sapiens OX=9606 GN=KANSL3 PE=1 SV=2 5.66 3883.2 - 1.13E+06 - - - 0.816 - 2.78 0.474 - 631 1 2 0 0.0011 14 0 0 0 6.73E+06 1.76E+06 - - - 5.1074 1 230117_WJC_METTL3_WT_vs_EV_F01.21420.21420.2 4.18E-10 13/28 K.LLMSEDYFTQAMEVK[136.11].A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1811.8565 -1 7892 21420 2 1811.851796 906.9355 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.14 3883.7 - 827052 - - - -2.6012 - 2.942 0.603 - 473.8 1 2 0 -0.0047 15 0 0 0 0.00E+00 0.00E+00 - - - 6.1463 0.9109 230117_WJC_METTL3_WT_vs_EV_F01.21421.21421.2 0.485 Jun-32 R.ASSGGGAGGAAGYAPVK.Y sp|P25067|CO8A2_HUMAN 1 1376.6684 2.19 7893 21421 2 1376.66455 689.3415 Collagen alpha-2(VIII) chain OS=Homo sapiens OX=9606 GN=COL8A2 PE=1 SV=2 8.63 3883.8 - 748184 - - - -2.8271 - 1.24 0.112 - 55.3 1 2 0 -0.0039 17 0 0 0 4.72E+06 2.16E+06 - - - 0.3959 1 230117_WJC_METTL3_WT_vs_EV_F01.21422.21422.2 5.72E-07 14/26 R.IPDVAALSMGFSVK.E "sp|O75787|RENR_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GV24|A0A1B0GV24_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GW13|A0A1B0GW13_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN,tr|A0A1B0GV60|A0A1B0GV60_HUMAN" 12 1433.7588 2.78 7894 21422 2 1433.760756 717.8867 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 5.84 3883.9 - 732379 - - - 1.3384 - 2.388 0.532 - 409.7 1 2 0 0.0019 14 0 0 0 6.17E+06 2.22E+06 - - - 5.1541 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.21423.21423.2 0.00398 16-Nov K.IPALDLLIK.L "sp|P78527|PRKDC_HUMAN,tr|F5GX40|F5GX40_HUMAN" 2 994.6427 1.07 7895 21423 2 994.644084 498.3286 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 3884.1 - 654385 - - - 1.4226 - 2 0.14 - 293.4 1 2 0 0.0014 9 0 0 0 4.11E+06 3.84E+06 - - - 2.0799 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21426.21426.2 1.80E-05 28-Sep K.LLMSEDYFTQAMEVK.A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1803.8423 -1 7897 21426 2 1803.841675 902.9284 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.14 3884.4 - 212620 - - - -0.3515 - 2.132 0.483 - 65.3 1 2 0 -0.0006 15 0 0 0 0.00E+00 0.00E+00 - - - 4.4695 1 230117_WJC_METTL3_WT_vs_EV_F01.21428.21428.2 7.43E-06 13/24 R.VVSTFGVIFDPVK.Q sp|Q9P2D1|CHD7_HUMAN 1 1406.781 0.79 7899 21428 2 1406.781616 704.3978 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 5.81 3884.6 - 4.78E+06 - - - 0.4713 - 2.503 0.609 - 502.9 1 2 0 0.0007 13 0 0 0 1.22E+07 1.53E+07 - - - 5.8936 0.9885 230117_WJC_METTL3_WT_vs_EV_F01.21429.21429.2 0.133 22-Jun R.GLFIIDPNGVIK.H sp|P30048|PRDX3_HUMAN 1 1284.7442 2.28 7900 21429 2 1284.744221 643.3794 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3884.6 - 3.04E+06 - - - 0.0366 - 1.254 0.135 - 84.3 1 2 0 0 12 0 0 0 3.51E+07 1.54E+07 - - - 0.6336 1 230117_WJC_METTL3_WT_vs_EV_F01.21431.21431.2 1.83E-05 18/26 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.41 7902 21431 2 1672.882545 837.4479 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3884.8 - 2.73E+06 - - - 0.7885 - 3.334 0.595 - 1544.2 1 2 0 0.0013 14 0 0 0 2.54E+07 6.19E+07 - - - 6.4571 1 230117_WJC_METTL3_WT_vs_EV_F01.21433.21433.2 5.00E-05 18-Oct R.AEVWDLDMLR.S sp|Q6P2E9|EDC4_HUMAN 1 1246.6016 1.65 7904 21433 2 1246.599971 624.3081 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 4.03 3885 - 2.19E+06 - - - -1.3132 - 2.226 0.483 - 539.2 1 2 0 -0.0016 10 0 0 0 4.21E+06 2.55E+06 - - - 4.8415 1 230117_WJC_METTL3_WT_vs_EV_F01.21435.21435.2 0.00315 13/24 K.DAAIYLVTSLASK.A sp|P55060|XPO2_HUMAN 1 1350.7395 0.84 7906 21435 2 1350.73979 676.377 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.83 3885.1 - 1.89E+06 - - - 0.228 - 2.535 0.501 - 483.6 1 2 0 0.0003 13 0 0 0 5.89E+06 7.04E+06 - - - 5.1287 1 230117_WJC_METTL3_WT_vs_EV_F01.21440.21440.2 1.79E-07 30-Aug R.LFVGNLPADITEDEFK[136.11].R sp|P23246|SFPQ_HUMAN 1 1814.9182 -1 7911 21440 2 1814.921737 908.4664 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3885.6 - 582587 - - - 1.9593 - 2.152 0.609 - 120.9 1 2 0 0.0036 16 0 0 0 0.00E+00 0.00E+00 - - - 5.4222 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.21445.21445.2 0.0103 14-Aug R.FPLFGGWK.T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 950.5014 1.74 7915 21445 2 950.501576 476.258 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3886.3 - 2.52E+06 - - - 0.1599 - 1.596 0.321 - 249.1 1 2 0 0.0002 8 0 0 0 4.66E+07 2.67E+07 - - - 2.8218 1 230117_WJC_METTL3_WT_vs_EV_F01.21447.21447.3 4.38E-08 24/52 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.86 7916 21447 3 1672.883043 558.6344 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3886.5 - 5.96E+06 - - - 1.0862 - 3.775 0.52 - 1025.7 1 2 0 0.0018 14 0 0 0 3.46E+07 4.04E+07 - - - 7.8673 1 230117_WJC_METTL3_WT_vs_EV_F01.21449.21449.2 6.80E-08 21/26 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.41 7918 21449 2 1662.873384 832.4438 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3886.7 - 6.07E+06 - - - 0.2574 - 3.656 0.616 - 2008.5 1 2 0 0.0004 14 0 0 0 2.54E+07 6.19E+07 - - - 6.8438 1 230117_WJC_METTL3_WT_vs_EV_F01.21450.21450.2 8.80E-07 18/26 K.LFSLELVDESGEIR[166.11].A sp|P27694|RFA1_HUMAN 1 1615.8333 0.05 7919 21450 2 1615.830511 808.9239 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4 3886.8 - 3.25E+06 - - - -1.7093 - 3.155 0.525 - 1542.6 1 2 0 -0.0028 14 0 0 0 1.64E+06 3.01E+07 - - - 5.8011 1 230117_WJC_METTL3_WT_vs_EV_F01.21451.21451.2 1.22E-08 15/24 R.TGTLVEEAFWIDK[136.11].L "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 1515.7701 0.63 7920 21451 2 1515.760642 758.8923 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.14 3887 - 1.93E+06 - - - -6.214 - 2.775 0.625 - 999.7 1 2 0 -0.0094 13 0 0 0 4.94E+06 7.80E+06 - - - 6.2738 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.21452.21452.2 9.28E-08 15/24 R.FGQDIISPLLSVK.E "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V414|A0A7I2V414_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|J3KNG4|J3KNG4_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|G3V5F3|G3V5F3_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|A0A7I2V4B9|A0A7I2V4B9_HUMAN,tr|H0YJY1|H0YJY1_HUMAN,tr|H0YJS6|H0YJS6_HUMAN,tr|G3V363|G3V363_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2V5R9|A0A7I2V5R9_HUMAN,tr|G3V4I1|G3V4I1_HUMAN,tr|A0A7I2V3Y3|A0A7I2V3Y3_HUMAN" 24 1415.8024 1.45 7921 21452 2 1415.802982 708.9085 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 5.84 3887 - 1.82E+06 - - - 0.3991 - 2.409 0.218 - 660.1 1 2 0 0.0006 13 0 0 0 2.25E+07 1.55E+07 - - - 2.9075 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21453.21453.2 0.00146 13/22 R.GLFIIDPNGVIK[136.11].H sp|P30048|PRDX3_HUMAN 1 1292.7584 2.28 7922 21453 2 1292.760637 647.3865 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3887.2 - 857166 - - - 1.7505 - 2.282 0.309 - 401.2 1 2 0 0.0023 12 0 0 0 3.51E+07 1.54E+07 - - - 3.4934 1 230117_WJC_METTL3_WT_vs_EV_F01.21456.21456.2 7.24E-06 14/32 R.LWVGGLGPNTSLAALAR.E sp|Q8NDT2|RB15B_HUMAN 1 1694.9468 -1 7925 21456 2 1694.946115 848.4807 Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3 9.75 3887.6 - 456021 - - - -0.3982 - 2.777 0.544 - 421.7 1 2 0 -0.0007 17 0 0 0 0.00E+00 0.00E+00 - - - 5.5699 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21457.21457.2 0.000205 18-Oct K.DAITQALFLR[166.11].E sp|Q9UNX4|WDR3_HUMAN 1 1156.648 1.07 7926 21457 2 1156.649093 579.3313 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.84 3887.7 - 445105 - - - 0.964 - 2.33 0.33 - 268.1 1 2 0 0.0011 10 0 0 0 1.73E+07 1.63E+07 - - - 3.8391 1 230117_WJC_METTL3_WT_vs_EV_F01.21458.21458.2 0.000303 18-Oct K.DAITQALFLR.E sp|Q9UNX4|WDR3_HUMAN 1 1146.6397 0.86 7927 21458 2 1146.641078 574.3271 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.84 3887.8 - 438689 - - - 1.1948 - 2.375 0.483 - 280.9 1 2 0 0.0014 10 0 0 0 1.80E+07 2.09E+07 - - - 5.0225 1 230117_WJC_METTL3_WT_vs_EV_F01.21459.21459.2 1.02E-07 14/26 R.SAAQMEVASFLLSK.E sp|Q12834|CDC20_HUMAN 1 1480.7596 -1 7928 21459 2 1480.762744 741.3871 Cell division cycle protein 20 homolog OS=Homo sapiens OX=9606 GN=CDC20 PE=1 SV=2 5.72 3888 - 352913 - - - 2.1462 - 2.849 0.547 - 789.5 1 2 0 0.0032 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7075 1 230117_WJC_METTL3_WT_vs_EV_F01.21460.21460.2 3.59E-08 17/32 R.LWVGGLGPNTSLAALAR[166.11].E sp|Q8NDT2|RB15B_HUMAN 1 1704.9551 -1 7929 21460 2 1704.953957 853.4848 Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3 9.75 3888.1 - 341742 - - - -0.6469 - 3.021 0.599 - 786.3 1 2 0 -0.0011 17 0 0 0 0.00E+00 0.00E+00 - - - 6.183 0.9954 230117_WJC_METTL3_WT_vs_EV_F01.21461.21461.2 0.249 30-Jul R.LFVGNLPADITEDEFK.R sp|P23246|SFPQ_HUMAN 1 1806.904 -1 7930 21461 2 1806.90368 904.4593 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3888.2 - 271076 - - - -0.1666 - 1.222 0.273 - 27.6 2 2 0 -0.0003 16 0 0 0 0.00E+00 0.00E+00 - - - 1.4157 1 230117_WJC_METTL3_WT_vs_EV_F01.21463.21463.2 3.19E-08 16/30 R.IGNVEISQVTIVGIIR[166.11].H "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 1720.0122 -1 7932 21463 2 1720.010377 861.0134 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 6 3888.5 - 245238 - - - -1.0831 - 3.34 0.604 - 876.5 1 2 0 -0.0019 16 0 0 0 0.00E+00 0.00E+00 - - - 6.4665 0.9935 230117_WJC_METTL3_WT_vs_EV_F01.21464.21464.2 0.076 24-Nov R.MLAIYDGFDGFAK.G "sp|Q01813|PFKAP_HUMAN,tr|H0Y3Y3|H0Y3Y3_HUMAN,tr|A0A7I2V3Z0|A0A7I2V3Z0_HUMAN,tr|B1APP6|B1APP6_HUMAN" 4 1446.6853 -1 7933 21464 2 1446.684677 724.3499 "ATP-dependent 6-phosphofructokinase, platelet type OS=Homo sapiens OX=9606 GN=PFKP PE=1 SV=2" 4.21 3888.6 - 215997 - - - -0.4569 - 1.528 0.155 - 184.3 1 2 0 -0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 1.2737 1 230117_WJC_METTL3_WT_vs_EV_F01.21472.21472.2 0.000161 22-Dec R.NFGASLLLPGLK[136.11].Q "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN,tr|D6RJC7|D6RJC7_HUMAN" 4 1236.7322 1.69 7940 21472 2 1236.733077 619.3734 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 8.75 3889.3 - 1.42E+06 - - - 0.7423 - 2.112 0.565 - 426.8 1 2 0 0.0009 12 0 0 0 3.15E+07 1.86E+07 - - - 5.181 1 230117_WJC_METTL3_WT_vs_EV_F01.21474.21474.2 8.36E-08 15/26 K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.77 7942 21474 2 1651.933658 826.9731 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3889.4 - 849358 - - - 1.2174 - 2.599 0.607 - 667.6 1 2 0 0.002 14 0 0 0 1.08E+08 1.40E+08 - - - 5.9205 1 230117_WJC_METTL3_WT_vs_EV_F01.21475.21475.2 0.000122 22-Dec K.SLPVSVPVWGFK.E sp|Q96B36|AKTS1_HUMAN 1 1314.7336 4.61 7943 21475 2 1314.734989 658.3741 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 8.47 3889.4 - 542864 - - - 1.0496 - 2.021 0.505 - 413.9 1 2 0 0.0014 12 0 0 0 7.59E+06 1.65E+06 - - - 4.6218 0.9553 230117_WJC_METTL3_WT_vs_EV_F01.21479.21479.2 0.0714 24-Aug R.LLSTEWGLPSIVK.S "sp|Q9Y3B1|PLD3B_HUMAN,tr|E9PL81|E9PL81_HUMAN" 2 1441.8181 -1 7947 21479 2 1441.824616 721.9163 PRELI domain containing protein 3B OS=Homo sapiens OX=9606 GN=PRELID3B PE=1 SV=2 6 3889.9 - 0 - - - 4.5422 - 1.428 0.098 - 85.1 2 2 0 0.0065 13 0 0 0 0.00E+00 0.00E+00 - - - 0.5427 1 230117_WJC_METTL3_WT_vs_EV_F01.21485.21485.2 9.35E-09 26-Dec K.LYTLVTYVPVTTFK.N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1643.9174 0.77 7952 21485 2 1643.917637 822.966 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3890.6 - 8.49E+06 - - - 0.1156 - 2.458 0.617 - 490.5 1 2 0 0.0002 14 0 0 0 1.08E+08 1.40E+08 - - - 5.855 1 230117_WJC_METTL3_WT_vs_EV_F01.21486.21486.2 6.42E-12 18/34 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.88 7953 21486 2 1936.013004 969.0131 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3890.7 - 2.62E+06 - - - 0.7309 - 4.061 0.669 - 847.6 1 2 0 0.0014 18 0 0 0 3.77E+07 4.30E+07 - - - 7.4273 1 230117_WJC_METTL3_WT_vs_EV_F01.21487.21487.3 1.18E-10 21/68 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.86 7954 21487 3 1936.011865 646.3445 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3890.7 - 2.47E+06 - - - 0.1426 - 3.118 0.671 - 479.4 1 2 0 0.0003 18 0 0 0 2.34E+07 2.72E+07 - - - 8.8526 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21488.21488.3 0.00153 Sep-52 K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.77 7955 21488 3 1651.933236 551.6512 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3890.8 - 2.44E+06 - - - 0.9619 - 1.771 0.328 - 58.6 1 2 0 0.0016 14 0 0 0 1.58E+07 2.06E+07 - - - 3.7153 1 230117_WJC_METTL3_WT_vs_EV_F01.21490.21490.2 3.04E-12 21/34 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.88 7957 21490 2 1926.004007 964.0089 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3890.9 - 1.91E+06 - - - 0.3572 - 4.173 0.713 - 1284.4 1 2 0 0.0007 18 0 0 0 3.77E+07 4.30E+07 - - - 7.8194 1 230117_WJC_METTL3_WT_vs_EV_F01.21493.21493.2 0.000648 13/24 K.NVLIVEDIIDTGK.T sp|P00492|HPRT_HUMAN 1 1427.7872 1.11 7960 21493 2 1427.789813 714.9009 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.03 3891.1 - 850486 - - - 1.8574 - 2.643 0.515 - 531 1 2 0 0.0027 13 0 0 0 9.74E+06 8.79E+06 - - - 5.3384 1 230117_WJC_METTL3_WT_vs_EV_F01.21494.21494.2 0.000304 13/20 K.LLTQYILNLGK.Y sp|O00203|AP3B1_HUMAN 1 1274.7598 1.45 7961 21494 2 1274.761981 638.3872 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 8.59 3891.2 - 613391 - - - 1.6921 - 2.583 0.512 - 633.1 1 2 0 0.0022 11 0 0 0 1.09E+07 7.56E+06 - - - 5.3891 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21497.21497.2 0.00291 18-Oct R.GVVLFPWQAR.L sp|Q9Y2S7|PDIP2_HUMAN 1 1171.6502 2.01 7964 21497 2 1171.651122 586.8324 Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1 9.75 3891.4 - 484132 - - - 0.775 - 1.895 0.345 - 327.2 1 2 0 0.0009 10 0 0 0 4.85E+06 2.41E+06 - - - 3.3731 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21500.21500.2 0.000121 20-Oct K.VLAISDLVIYR.T "sp|Q9HBF4|ZFYV1_HUMAN,tr|G3V5N8|G3V5N8_HUMAN" 2 1260.7442 -1 7967 21500 2 1260.745137 631.3794 Zinc finger FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZFYVE1 PE=1 SV=1 5.81 3891.7 - 283199 - - - 0.7638 - 2.162 0.393 - 388.7 1 2 0 0.001 11 0 0 0 0.00E+00 0.00E+00 - - - 4.0292 1 230117_WJC_METTL3_WT_vs_EV_F01.21503.21503.2 6.12E-05 22-Dec R.LFQVEYAIEAIK.L sp|P28066|PSA5_HUMAN 1 1422.7759 2.06 7968 21503 2 1422.777588 712.3952 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 4.53 3892.1 - 2.05E+06 - - - 1.2089 - 2.395 0.447 - 447.8 1 2 0 0.0017 12 0 0 0 3.37E+07 1.64E+07 - - - 4.64 1 230117_WJC_METTL3_WT_vs_EV_F01.21505.21505.3 8.84E-09 22/68 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.86 7970 21505 3 1926.004369 643.0084 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3892.3 - 2.06E+06 - - - 0.5452 - 2.943 0.57 - 377.9 1 2 0 0.001 18 0 0 0 2.34E+07 2.72E+07 - - - 7.5825 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.21506.21506.2 0.388 16-Oct K.SLDIYSFIK.E "sp|Q9NR50|EI2BG_HUMAN,tr|H0Y580|H0Y580_HUMAN" 2 1084.5805 0.73 7971 21506 2 1084.580279 543.2975 Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens OX=9606 GN=EIF2B3 PE=1 SV=1 5.55 3892.4 - 817793 - - - -0.1687 - 1.746 0.321 - 273.9 1 2 0 -0.0002 9 0 0 0 7.63E+06 1.05E+07 - - - 3.0242 1 230117_WJC_METTL3_WT_vs_EV_F01.21508.21508.2 0.000307 16/24 R.VLGATLLPDLIQK.V "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN,tr|H0YDG0|H0YDG0_HUMAN" 5 1379.8388 1.64 7973 21508 2 1379.83961 690.9267 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.81 3892.7 - 636244 - - - 0.5856 - 2.838 0.515 - 762.9 1 2 0 0.0008 13 0 0 0 1.14E+07 6.96E+06 - - - 5.5217 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.21509.21509.3 0.0037 Nov-40 R.SIIGMIDMFHK.Y "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1290.6464 999 7974 21509 3 1290.646283 431.2228 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.46 3892.8 - 617103 - - - -0.1294 - 2.214 0.47 - 118.1 1 2 0 -0.0002 11 0 0 0 7.53E+06 0.00E+00 - - - 6.0379 1 230117_WJC_METTL3_WT_vs_EV_F01.21510.21510.2 0.000163 20-Nov R.EALDVLGAVLK[136.11].A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1134.674 1.32 7975 21510 2 1134.674704 568.3443 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3892.9 - 587889 - - - 0.6425 - 2.208 0.51 - 325.8 1 2 0 0.0007 11 0 0 0 6.45E+07 4.90E+07 - - - 4.9504 1 230117_WJC_METTL3_WT_vs_EV_F01.21512.21512.2 1.14E-05 14/20 R.EALDVLGAVLK.A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1126.6598 1.32 7977 21512 2 1126.661015 564.3372 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3893.2 - 527807 - - - 1.1006 - 2.454 0.488 - 664.7 1 2 0 0.0012 11 0 0 0 6.45E+07 4.90E+07 - - - 5.0735 1 230117_WJC_METTL3_WT_vs_EV_F01.21513.21513.2 1.73E-05 15/24 R.VLGATLLPDLIQK[136.11].V "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN,tr|H0YDG0|H0YDG0_HUMAN" 5 1387.853 1.64 7978 21513 2 1387.855139 694.9338 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.81 3893.3 - 420497 - - - 1.5398 - 2.719 0.563 - 725.3 1 2 0 0.0021 13 0 0 0 1.14E+07 6.96E+06 - - - 5.7659 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21514.21514.2 2.17E-05 18-Sep K.DWVFLNYTYK[136.11].R "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN" 2 1355.6641 0.25 7979 21514 2 1355.663756 678.8393 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.83 3893.4 - 418819 - - - -0.2825 - 2.057 0.451 - 285.8 1 2 0 -0.0004 10 0 0 0 1.01E+06 4.03E+06 - - - 4.3852 1 230117_WJC_METTL3_WT_vs_EV_F01.21519.21519.2 3.60E-05 20-Nov K.TLC[160.03]PLC[160.03]FSILK.G "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1350.704 1.14 7984 21519 2 1350.703098 676.3593 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 7.74 3894.1 - 346872 - - - -0.6426 - 2.074 0.502 - 317.9 1 2 0 -0.0009 11 0 0 0 4.51E+06 3.95E+06 - - - 4.7219 1 230117_WJC_METTL3_WT_vs_EV_F01.21521.21521.2 0.000847 14/28 R.TIAIIAEGIPEALTR.K sp|P53396|ACLY_HUMAN 1 1566.8981 -1 7986 21521 2 1566.900778 784.4563 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.53 3894.4 - 233408 - - - 1.704 - 2.883 0.522 - 690.8 1 2 0 0.0027 15 0 0 0 0.00E+00 0.00E+00 - - - 5.4988 1 230117_WJC_METTL3_WT_vs_EV_F01.21527.21527.2 0.0013 20-Dec K.IALLNVELELK.A sp|Q99832|TCPH_HUMAN 1 1253.7595 12.52 7991 21527 2 1253.761077 627.887 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.53 3894.9 - 2.11E+06 - - - 1.2666 - 2.557 0.445 - 597.7 1 2 0 0.0016 11 0 0 0 1.18E+08 9.39E+06 - - - 4.867 1 230117_WJC_METTL3_WT_vs_EV_F01.21530.21530.2 4.77E-06 18-Aug R.VYNALVAFIR.A sp|Q9BW92|SYTM_HUMAN 1 1164.6655 0.52 7994 21530 2 1164.669322 583.34 "Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1" 8.72 3895.2 - 399297 - - - 3.2567 - 2.025 0.558 - 195.5 1 2 0 0.0038 10 0 0 0 3.96E+06 7.56E+06 - - - 5.1307 1 230117_WJC_METTL3_WT_vs_EV_F01.21532.21532.2 2.77E-10 14/26 R.VIVSDVQESFIWVR.Y sp|Q15393|SF3B3_HUMAN 1 1675.8934 1.39 7996 21532 2 1675.892775 838.954 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3895.4 - 293988 - - - -0.3473 - 2.93 0.564 - 568.5 1 2 0 -0.0006 14 0 0 0 1.16E+07 8.36E+06 - - - 5.9042 1 230117_WJC_METTL3_WT_vs_EV_F01.21534.21534.2 3.58E-08 24-Oct K.FDFPVSYLPGPVK.A "sp|Q9NXE4|NSMA3_HUMAN,tr|A0A7P0T8J0|A0A7P0T8J0_HUMAN,tr|A0A7P0Z453|A0A7P0Z453_HUMAN,tr|C9J647|C9J647_HUMAN,tr|A0A7P0TAZ0|A0A7P0TAZ0_HUMAN,tr|A0A7P0T9J6|A0A7P0T9J6_HUMAN,tr|A0A7P0TB24|A0A7P0TB24_HUMAN" 7 1464.7653 3.5 7998 21534 2 1464.766236 733.3899 Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3 5.83 3895.6 - 196076 - - - 0.637 - 2.072 0.609 - 244.1 1 2 0 0.0009 13 0 0 0 3.78E+06 1.08E+06 - - - 5.4085 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21543.21543.2 0.0152 13/18 K.LLEPVLLLGK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1093.7111 1.68 8005 21543 2 1093.711147 547.8628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3896.6 - 4.07E+06 - - - 0.0585 - 2.518 0.313 - 508.3 1 2 0 0.0001 10 0 0 0 7.65E+08 4.57E+08 - - - 3.9305 1 230117_WJC_METTL3_WT_vs_EV_F01.21544.21544.2 0.000219 15/18 K.C[160.03]MQLTDFILK[136.11].F "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1275.6447 0.68 8006 21544 2 1275.647565 638.8296 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.83 3896.7 - 3.84E+06 - - - 2.2726 - 2.519 0.529 - 686.5 1 2 0 0.0029 10 0 0 0 1.41E+07 2.08E+07 - - - 5.5261 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.21545.21545.2 0.00198 15/18 K.LLEPVLLLGK[136.11].E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1101.7253 1.68 8007 21545 2 1101.728405 551.8699 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3896.8 - 3.00E+06 - - - 2.8337 - 2.454 0.312 - 681.8 1 2 0 0.0031 10 0 0 0 7.65E+08 4.57E+08 - - - 3.8503 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.21546.21546.2 0.0234 20-Nov K.IALLNVELELK[136.11].A sp|Q99832|TCPH_HUMAN 1 1261.7737 12.52 8008 21546 2 1261.776444 631.8941 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.53 3896.9 - 1.60E+06 - - - 2.1834 - 2.512 0.235 - 446.2 1 2 0 0.0028 11 0 0 0 1.18E+08 9.39E+06 - - - 3.2676 1 230117_WJC_METTL3_WT_vs_EV_F01.21547.21547.2 2.59E-07 14/26 R.VIVSDVQESFIWVR[166.11].Y sp|Q15393|SF3B3_HUMAN 1 1685.9016 1.58 8009 21547 2 1685.903211 843.9581 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3897.1 - 1.21E+06 - - - 0.9396 - 2.962 0.616 - 581 1 2 0 0.0016 14 0 0 0 1.32E+07 8.36E+06 - - - 6.3152 1 230117_WJC_METTL3_WT_vs_EV_F01.21550.21550.2 7.81E-08 24-Dec K.YVFLDPLAGAVTK[136.11].T "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|A8MWX3|WASH4_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 6 1400.7795 2.39 8012 21550 2 1400.782633 701.397 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 5.83 3897.4 - 648567 - - - 2.2345 - 2.354 0.593 - 354.8 1 2 0 0.0031 13 0 0 0 1.19E+07 4.99E+06 - - - 5.6172 1 230117_WJC_METTL3_WT_vs_EV_F01.21554.21554.2 1.27E-11 18/32 R.VLALSVETDYTFPLAEK[136.11].V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN" 5 1903.007 -1 8016 21554 2 1903.007914 952.5108 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 4.14 3898 - 409003 - - - 0.4824 - 4.237 0.692 - 893 1 2 0 0.0009 17 0 0 0 0.00E+00 0.00E+00 - - - 7.7016 0.9944 230117_WJC_METTL3_WT_vs_EV_F01.21556.21556.2 0.195 14-Sep K.QFLIDWVR.K "sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 2 1075.5815 -1 8018 21556 2 1075.58585 538.798 ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2 5.84 3898.2 - 383060 - - - 4.0769 - 1.672 0.187 - 225.1 1 2 0 0.0044 8 0 0 0 0.00E+00 0.00E+00 - - - 1.9711 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.21557.21557.2 8.10E-05 22-Nov R.IAAQDYIIGVFR[166.11].K "sp|Q96RR1|PEO1_HUMAN,tr|A0A2R8Y4V4|A0A2R8Y4V4_HUMAN,tr|A0A2R8Y746|A0A2R8Y746_HUMAN" 3 1374.7535 0.82 8019 21557 2 1374.759527 688.384 Twinkle mtDNA helicase OS=Homo sapiens OX=9606 GN=TWNK PE=1 SV=1 5.84 3898.4 - 381532 - - - 4.3797 - 2.305 0.37 - 297.5 1 2 0 0.006 12 0 0 0 4.27E+06 5.21E+06 - - - 3.9692 1 230117_WJC_METTL3_WT_vs_EV_F01.21560.21560.2 6.27E-06 14/20 K.DPWDAVLLEER[166.11].S "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 1351.6648 2.11 8022 21560 2 1351.667453 676.8397 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 3.92 3898.7 - 343020 - - - 1.999 - 2.878 0.612 - 990.2 1 2 0 0.0027 11 0 0 0 4.53E+06 2.15E+06 - - - 6.4201 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21561.21561.2 0.000325 13/24 K.ALEVAEYLTPVLK.E "sp|Q9NT62|ATG3_HUMAN,tr|F8WDI0|F8WDI0_HUMAN" 2 1444.8177 2.69 8023 21561 2 1444.820288 723.4161 Ubiquitin-like-conjugating enzyme ATG3 OS=Homo sapiens OX=9606 GN=ATG3 PE=1 SV=1 4.53 3898.9 - 298894 - - - 1.7684 - 2.41 0.362 - 623.6 1 2 0 0.0026 13 0 0 0 2.59E+06 9.63E+05 - - - 3.9715 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.21564.21564.2 0.0425 16-Sep R.WLTYFMAVK[136.11].S "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1165.6085 -1 8025 21564 2 1165.611162 583.8115 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 8.59 3899.2 - 99570 - - - 2.2512 - 1.453 0.255 - 161.7 1 2 0 0.0026 9 0 0 0 0.00E+00 0.00E+00 - - - 2.0045 1 230117_WJC_METTL3_WT_vs_EV_F01.21565.21565.2 1.03E-05 18-Nov K.LFEISDIVIK.D sp|Q9NSD9|SYFB_HUMAN 1 1175.6802 1.59 8026 21565 2 1175.680982 588.8474 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 4.37 3899.3 - 981038 - - - 0.6856 - 2.151 0.518 - 350.2 1 2 0 0.0008 10 0 0 0 1.11E+07 6.96E+06 - - - 5.0046 1 230117_WJC_METTL3_WT_vs_EV_F01.21566.21566.2 0.00796 18-Nov K.QEVPIIIVFR[166.11].A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1222.7313 1.27 8027 21566 2 1222.731932 612.3729 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3899.4 - 572889 - - - 0.5054 - 2.126 0.504 - 482 1 2 0 0.0006 10 0 0 0 2.00E+07 1.58E+07 - - - 4.8687 1 230117_WJC_METTL3_WT_vs_EV_F01.21568.21568.2 1.18E-06 24-Dec R.LDPETLESLGLIK[136.11].Q "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 1434.8061 1.62 8029 21568 2 1434.813013 718.4103 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 4.14 3899.6 - 472695 - - - 4.8097 - 2.318 0.537 - 598.3 1 2 0 0.0069 13 0 0 0 1.71E+07 1.05E+07 - - - 5.1628 1 230117_WJC_METTL3_WT_vs_EV_F01.21569.21569.2 2.94E-05 22-Nov R.EVAAGYLVPLLR.S sp|Q13395|TARB1_HUMAN 1 1299.7551 2.77 8030 21569 2 1299.756419 650.8848 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6.1 3899.7 - 333167 - - - 1.0356 - 2.49 0.494 - 538.3 1 2 0 0.0013 12 0 0 0 2.01E+06 7.25E+05 - - - 5.0896 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21570.21570.2 0.00106 14-Sep K.SFDLLILK[136.11].E "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 955.5834 1.01 8031 21570 2 955.583782 478.799 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 5.55 3899.8 - 327972 - - - 0.4322 - 1.871 0.452 - 215 1 2 0 0.0004 8 0 0 0 5.17E+06 5.10E+06 - - - 4.2688 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.21571.21571.2 0.00377 14-Aug K.YLFDLPLK.V sp|Q5VUJ6|LRCH2_HUMAN 1 1007.5692 3.05 8032 21571 2 1007.57333 504.7919 Leucine-rich repeat and calponin homology domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LRCH2 PE=1 SV=2 5.83 3900 - 310224 - - - 4.1297 - 1.474 0.417 - 192.8 1 2 0 0.0042 8 0 0 0 2.39E+06 7.85E+05 - - - 3.2898 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.21572.21572.2 0.00431 18-Aug R.LIFQVLDAVK.Y "sp|Q14012|KCC1A_HUMAN,tr|C9JES6|C9JES6_HUMAN" 2 1144.6856 -1 8033 21572 2 1144.684551 573.3501 Calcium\calmodulin-dependent protein kinase type 1 OS=Homo sapiens OX=9606 GN=CAMK1 PE=1 SV=1 5.84 3900.1 - 260200 - - - -0.9129 - 1.542 0.272 - 122.8 1 2 0 -0.001 10 0 0 0 0.00E+00 0.00E+00 - - - 2.2585 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.21573.21573.2 0.00208 18-Aug K.EYLPFLNTLK[136.11].K "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN" 12 1244.6896 2.15 8034 21573 2 1244.694118 623.3521 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 6.1 3900.2 - 224070 - - - 3.6097 - 1.605 0.298 - 150.2 1 2 0 0.0045 10 0 0 0 3.65E+06 1.70E+06 - - - 2.5612 1 230117_WJC_METTL3_WT_vs_EV_F01.21574.21574.2 2.41E-07 22-Dec R.LGAPGFAWEPFR.G "sp|Q9HCM7|FBSL_HUMAN,tr|A0A3B3IRR3|A0A3B3IRR3_HUMAN,tr|A0A7P0Z485|A0A7P0Z485_HUMAN" 3 1346.6772 2.68 8035 21574 2 1346.6748 674.3459 Fibrosin-1-like protein OS=Homo sapiens OX=9606 GN=FBRSL1 PE=1 SV=4 6 3900.3 - 214564 - - - -1.7502 - 2.438 0.536 - 557.5 1 2 0 -0.0024 12 0 0 0 1.90E+06 7.09E+05 - - - 5.344 1 230117_WJC_METTL3_WT_vs_EV_F01.21575.21575.2 7.28E-07 20-Oct R.FVASYLEYAFR[166.11].K sp|Q96GM8|TOE1_HUMAN 1 1374.6848 -1 8036 21575 2 1374.679645 688.3497 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 6 3900.4 - 168992 - - - -3.7194 - 2.169 0.547 - 283.7 1 2 0 -0.0051 11 0 0 0 0.00E+00 0.00E+00 - - - 5.1741 0.9676 230117_WJC_METTL3_WT_vs_EV_F01.21577.21577.2 3.04 26-Jun K.KAC[160.03]TGLSGPGSGSK[136.11].S "tr|I3L2J0|I3L2J0_HUMAN,tr|A0A7P0T9K5|A0A7P0T9K5_HUMAN" 2 1313.6489 - 8038 21577 2 1313.650602 657.8317 Protein capicua homolog OS=Homo sapiens OX=9606 GN=CIC PE=1 SV=1 9.31 3900.7 - 177926 - - - 1.2956 - 1.178 0.068 - 96.5 4 2 0 0.0017 14 0 0 0 - - - - - -0.3151 1 230117_WJC_METTL3_WT_vs_EV_F01.21587.21587.2 0.000567 18-Nov K.QEVPIIIVFR.A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1212.723 1.27 8046 21587 2 1212.723906 607.3688 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3902 - 475421 - - - 0.7108 - 2.108 0.512 - 444.4 1 2 0 0.0009 10 0 0 0 2.00E+07 1.58E+07 - - - 4.9039 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21588.21588.2 0.000306 16-Sep R.DIDAFWLQR[166.11].Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1172.5854 1.56 8047 21588 2 1172.585934 587.3 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3902.1 - 1.13E+06 - - - 0.4742 - 1.813 0.439 - 265.5 1 2 0 0.0006 9 0 0 0 2.38E+07 1.53E+07 - - - 4.0046 0.9928 230117_WJC_METTL3_WT_vs_EV_F01.21592.21592.2 0.0352 16-May R.MDPAWHPWL.- "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1151.5222 - 8051 21592 2 1151.522019 576.7684 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 5.06 3902.4 - 400293 - - - -0.1884 - 1.086 0.243 - 62.6 1 2 0 -0.0002 9 0 0 0 - - - - - 1.0744 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.21599.21599.2 1.48E-05 22-Sep R.EVAAGYLVPLLR[166.11].S sp|Q13395|TARB1_HUMAN 1 1309.7633 -1 8058 21599 2 1309.763906 655.8889 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6.1 3903.1 - 0 - - - 0.4298 - 2.005 0.328 - 267.3 1 2 0 0.0006 12 0 0 0 0.00E+00 0.00E+00 - - - 3.2938 1 230117_WJC_METTL3_WT_vs_EV_F01.21600.21600.2 4.69E-09 13/24 K.TVQTAVFLYSLYK.E "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 1531.8286 -1 8059 21600 2 1531.828226 766.9216 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.17 3903.2 - 0 - - - -0.265 - 2.742 0.59 - 444.2 1 2 0 -0.0004 13 0 0 0 0.00E+00 0.00E+00 - - - 5.9874 1 230117_WJC_METTL3_WT_vs_EV_F01.21602.21602.2 4.04E-06 16/24 K.VFSATLGLVDIVK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1368.8108 1.1 8061 21602 2 1368.817008 685.4127 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3903.5 - 0 - - - 4.5331 - 2.784 0.559 - 710.9 1 2 0 0.0062 13 0 0 0 1.21E+08 1.10E+08 - - - 5.7957 0.9783 230117_WJC_METTL3_WT_vs_EV_F01.21603.21603.2 1.45E-06 15/26 Y.VAIQAVLSLYASGR[166.11].T "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 19 1456.8277 0.8 8062 21603 2 1456.829026 729.4211 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 8.72 3903.6 - 0 - - - 0.8869 - 2.804 0.378 - 972 1 1 0 0.0013 14 0 0 0 2.12E+06 2.66E+06 - - - 4.4199 1 230117_WJC_METTL3_WT_vs_EV_F01.21604.21604.2 1.89E-08 Nov-32 R.EIISEMGELGVLGPTIK.G "sp|Q92947|GCDH_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKT3|K7EKT3_HUMAN" 3 1784.9594 -1 8063 21604 2 1784.95911 893.487 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.25 3903.8 - 0 - - - -0.1557 - 2.659 0.596 - 271.5 1 2 0 -0.0003 17 0 0 0 0.00E+00 0.00E+00 - - - 5.8473 0.8841 230117_WJC_METTL3_WT_vs_EV_F01.21610.21610.2 0.256 14-Jul N.GVSQLIQR.E sp|P48201|AT5G3_HUMAN 1 899.5189 0.86 8068 21610 2 899.519188 450.7667 "ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1" 9.75 3904.3 - 8.21E+06 - - - 0.3591 - 1.631 0.214 - 223.9 1 1 0 0.0003 8 0 0 0 9.01E+07 1.04E+08 - - - 2.0969 1 230117_WJC_METTL3_WT_vs_EV_F01.21611.21611.2 4.86E-05 13/24 K.VFSATLGLVDIVK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1360.7966 1.1 8069 21611 2 1360.797557 681.4056 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3904.4 - 4.68E+06 - - - 0.7011 - 2.558 0.539 - 445.4 1 2 0 0.001 13 0 0 0 1.21E+08 1.10E+08 - - - 5.4323 1 230117_WJC_METTL3_WT_vs_EV_F01.21612.21612.2 5.45E-08 15/28 K.IVFVPGC[160.03]SIPLTIVK.S sp|P54136|SYRC_HUMAN 1 1641.9528 1.54 8070 21612 2 1641.953476 821.9837 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3904.5 - 2.89E+06 - - - 0.4196 - 2.577 0.623 - 534.7 1 2 0 0.0007 15 0 0 0 3.37E+07 2.20E+07 - - - 5.9696 1 230117_WJC_METTL3_WT_vs_EV_F01.21614.21614.3 2.43E-06 24/52 K.LPLFPEPLHVFAPR.A "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|K7ENW7|K7ENW7_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 7 1631.9188 0.84 8072 21614 3 1631.923424 544.9802 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 6.75 3904.6 - 2.53E+06 - - - 2.8433 - 3.99 0.562 - 1130.9 1 2 0 0.0046 14 0 0 0 1.07E+07 1.27E+07 - - - 8.4819 1 230117_WJC_METTL3_WT_vs_EV_F01.21615.21615.2 0.00165 14/22 K.IILDLISESPIK.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1339.7963 1.17 8073 21615 2 1339.798824 670.9054 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3904.8 - 2.51E+06 - - - 1.907 - 2.784 0.526 - 644.9 1 2 0 0.0026 12 0 0 0 5.42E+08 4.62E+08 - - - 5.6193 1 230117_WJC_METTL3_WT_vs_EV_F01.21616.21616.2 7.33E-05 15/22 K.IILDLISESPIK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1347.8105 1.17 8074 21616 2 1347.811118 674.9125 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3904.9 - 2.44E+06 - - - 0.4815 - 2.828 0.507 - 745.1 1 2 0 0.0006 12 0 0 0 5.42E+08 4.62E+08 - - - 5.5208 1 230117_WJC_METTL3_WT_vs_EV_F01.21617.21617.2 2.76E-06 14/28 K.IVFVPGC[160.03]SIPLTIVK[136.11].S sp|P54136|SYRC_HUMAN 1 1649.967 1.54 8075 21617 2 1649.966915 825.9908 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3905 - 2.41E+06 - - - -0.0436 - 2.387 0.522 - 469.8 1 2 0 -0.0001 15 0 0 0 3.37E+07 2.20E+07 - - - 5.0355 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21620.21620.2 0.000115 14-Oct K.NFAFLEFR[166.11].S "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1052.5319 1.16 8078 21620 2 1052.53269 527.2732 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3905.3 - 1.64E+06 - - - 0.7639 - 1.795 0.334 - 533.9 1 2 0 0.0008 8 0 0 0 1.44E+07 1.24E+07 - - - 3.272 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.21621.21621.3 0.0107 Dec-48 R.FFVTTLPAFFHAK[136.11].D sp|Q9H1E5|TMX4_HUMAN 1 1532.8271 1.95 8079 21621 3 1532.834381 511.9497 Thioredoxin-related transmembrane protein 4 OS=Homo sapiens OX=9606 GN=TMX4 PE=1 SV=1 8.76 3905.5 - 1.47E+06 - - - 4.7357 - 2.193 0.32 - 97.6 1 2 0 0.0073 13 0 0 0 7.52E+06 3.85E+06 - - - 4.2348 1 230117_WJC_METTL3_WT_vs_EV_F01.21626.21626.2 1.23E-05 22-Dec K.VVYTSLQWASLQ.- "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN" 2 1393.7242 - 8084 21626 2 1393.719141 697.8694 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 5.49 3906.1 - 748831 - - - -3.6054 - 2.301 0.513 - 322.5 1 2 0 -0.005 12 0 0 0 - - - - - 5.0211 1 230117_WJC_METTL3_WT_vs_EV_F01.21629.21629.2 0.0749 16/24 K.LDNLLLDTEGFVK.L sp|Q16513|PKN2_HUMAN 1 1475.7872 -1 8086 21629 2 1475.790435 738.9009 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.03 3906.6 - 1.90E+06 - - - 2.2185 - 2.822 0.4 - 592.5 1 2 0 0.0033 13 0 0 0 0.00E+00 0.00E+00 - - - 4.657 1 230117_WJC_METTL3_WT_vs_EV_F01.21630.21630.2 2.22E-05 16-Oct R.DIDAFWLQR.Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1162.5771 1.56 8087 21630 2 1162.575911 582.2958 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3906.6 - 8.56E+06 - - - -1.0296 - 2.144 0.505 - 368.2 1 2 0 -0.0012 9 0 0 0 2.38E+07 1.53E+07 - - - 4.977 0.9942 230117_WJC_METTL3_WT_vs_EV_F01.21633.21633.2 3.35 16-Sep R.LLPDFLLER[166.11].R "sp|Q12894|IFRD2_HUMAN,tr|H7C444|H7C444_HUMAN,tr|A0A0R4J2F6|A0A0R4J2F6_HUMAN" 3 1124.6469 0.15 8090 21633 2 1124.646646 563.3307 Interferon-related developmental regulator 2 OS=Homo sapiens OX=9606 GN=IFRD2 PE=1 SV=3 4.37 3906.9 - 2.91E+06 - - - -0.2401 - 1.694 0.113 - 128.4 2 2 0 -0.0003 9 0 0 0 1.28E+06 8.56E+06 - - - 1.266 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.21637.21637.3 0.000488 Dec-48 R.LLGNTFVALSDLR.C "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1417.7929 3.77 8094 21637 3 1417.793528 473.6049 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.84 3907.5 - 1.55E+06 - - - 0.4324 - 1.966 0.446 - 212.2 1 2 0 0.0006 13 0 0 0 4.82E+06 1.28E+06 - - - 5.3451 0.9918 230117_WJC_METTL3_WT_vs_EV_F01.21640.21640.2 0.0666 24-Nov K.LDNLLLDTEGFVK[136.11].L sp|Q16513|PKN2_HUMAN 1 1483.8014 -1 8097 21640 2 1483.79828 742.908 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.03 3907.8 - 1.12E+06 - - - -2.0764 - 1.697 0.212 - 179.2 1 2 0 -0.0031 13 0 0 0 0.00E+00 0.00E+00 - - - 1.9632 1 230117_WJC_METTL3_WT_vs_EV_F01.21646.21646.2 2.30E-11 18/26 K.FGGDFLVYPGDPLR.F "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN" 4 1551.7722 999 8103 21646 2 1551.769995 776.8934 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.21 3908.6 - 839178 - - - -1.4074 - 3.311 0.671 - 1027 1 2 0 -0.0022 14 0 0 0 1.18E+07 0.00E+00 - - - 7.0008 0.8563 230117_WJC_METTL3_WT_vs_EV_F01.21647.21647.3 0.471 Aug-48 R.LLGNTFVALSDLR[166.11].C "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1427.8012 -1 8104 21647 3 1427.797444 476.941 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.84 3908.8 - 755660 - - - -2.6201 - 1.338 0.147 - 61 1 2 0 -0.0037 13 0 0 0 0.00E+00 0.00E+00 - - - 0.9673 1 230117_WJC_METTL3_WT_vs_EV_F01.21652.21652.2 1.71E-05 13/26 K.EIGLLADEIEIYGK.S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1561.8239 -1 8108 21652 2 1561.822142 781.9192 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4 3909.3 - 1.91E+06 - - - -1.1512 - 2.481 0.494 - 453.8 1 2 0 -0.0018 14 0 0 0 0.00E+00 0.00E+00 - - - 4.9694 0.9957 230117_WJC_METTL3_WT_vs_EV_F01.21654.21654.2 0.167 18-Oct K.VVLPTFILER.R sp|Q96SU4|OSBL9_HUMAN 1 1185.7121 -1 8110 21654 2 1185.709811 593.8633 Oxysterol-binding protein-related protein 9 OS=Homo sapiens OX=9606 GN=OSBPL9 PE=1 SV=2 5.97 3909.5 - 1.88E+06 - - - -1.9684 - 1.517 0.319 - 257.8 1 2 0 -0.0023 10 0 0 0 0.00E+00 0.00E+00 - - - 2.5596 1 230117_WJC_METTL3_WT_vs_EV_F01.21658.21658.2 2.53E-05 14-Sep R.FDMIFIVK.D "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1011.5463 2.07 8114 21658 2 1011.546589 506.7804 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 5.84 3910.1 - 898265 - - - 0.261 - 1.839 0.525 - 206.7 1 2 0 0.0003 8 0 0 0 3.24E+06 1.57E+06 - - - 4.756 1 230117_WJC_METTL3_WT_vs_EV_F01.21659.21659.2 3.70E-06 13/24 R.FDNVLPVSLAFDK.C "sp|O95352|ATG7_HUMAN,tr|H7BZ92|H7BZ92_HUMAN,tr|H7C2R3|H7C2R3_HUMAN,tr|H7C2J8|H7C2J8_HUMAN" 4 1463.766 -1 8115 21659 2 1463.764267 732.8903 Ubiquitin-like modifier-activating enzyme ATG7 OS=Homo sapiens OX=9606 GN=ATG7 PE=1 SV=1 4.21 3910.2 - 885570 - - - -1.2051 - 2.499 0.48 - 576.4 1 2 0 -0.0018 13 0 0 0 0.00E+00 0.00E+00 - - - 4.9364 1 230117_WJC_METTL3_WT_vs_EV_F01.21660.21660.2 8.19E-08 15/26 K.EIGLLADEIEIYGK[136.11].S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1569.8381 -1 8116 21660 2 1569.840409 785.9263 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4 3910.3 - 736549 - - - 1.4454 - 2.806 0.589 - 688.7 1 2 0 0.0023 14 0 0 0 0.00E+00 0.00E+00 - - - 5.9798 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.21670.21670.2 0.000371 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 850.99 8125 21670 2 1603.762534 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3911.6 - 1.61E+06 - - - -0.8767 - 1.82 0.487 - 169.1 1 2 0 -0.0014 12 0 0 0 2.07E+08 2.43E+05 - - - 4.2132 1 230117_WJC_METTL3_WT_vs_EV_F01.21675.21675.2 0.000957 16-Dec R.IDLAVLLGK.T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 940.5957 1.97 8130 21675 2 940.596105 471.3051 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3912 - 388214 - - - 0.4114 - 2.394 0.504 - 383.9 1 2 0 0.0004 9 0 0 0 5.74E+08 2.92E+08 - - - 5.289 1 230117_WJC_METTL3_WT_vs_EV_F01.21683.21683.2 0.00536 16-Dec R.IDLAVLLGK[136.11].T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 948.6099 1.97 8135 21683 2 948.609364 475.3122 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3913 - 3.04E+07 - - - -0.584 - 2.454 0.488 - 380.4 1 2 0 -0.0006 9 0 0 0 5.74E+08 2.92E+08 - - - 5.2423 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.21686.21686.2 0.00683 15/26 K.VLLLSSPGLEELYR.C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1587.8872 1.07 8138 21686 2 1587.885878 794.9509 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3913.4 - 3.78E+06 - - - -0.8382 - 2.665 0.346 - 680.2 1 2 0 -0.0013 14 0 0 0 3.51E+07 3.26E+07 - - - 4.0559 1 230117_WJC_METTL3_WT_vs_EV_F01.21687.21687.2 4.56E-05 20-Nov K.LPDVYGVFQFK.V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1311.6863 1.13 8139 21687 2 1311.687656 656.8504 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.83 3913.4 - 3.62E+06 - - - 1.0155 - 2.294 0.468 - 411.5 1 2 0 0.0013 11 0 0 0 2.54E+07 2.24E+07 - - - 4.7434 0.999 230117_WJC_METTL3_WT_vs_EV_F01.21690.21690.2 0.113 14-Aug K.ENLLDFIK[136.11].H "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 998.5528 2.18 8142 21690 2 998.552374 500.2837 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.37 3913.7 - 3.01E+06 - - - -0.4236 - 1.878 0.307 - 203.9 1 2 0 -0.0004 8 0 0 0 1.32E+08 6.07E+07 - - - 3.209 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.21694.21694.2 0.0106 16-Aug K.DLPPILLVR.G sp|P55011|S12A2_HUMAN 1 1034.6488 999 8146 21694 2 1034.649263 518.3317 Solute carrier family 12 member 2 OS=Homo sapiens OX=9606 GN=SLC12A2 PE=1 SV=1 5.84 3914 - 2.03E+06 - - - 0.4311 - 1.237 0.377 - 242.6 1 2 0 0.0004 9 0 0 0 5.38E+06 0.00E+00 - - - 2.4407 1 230117_WJC_METTL3_WT_vs_EV_F01.21695.21695.2 0.000357 14/24 R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 1.53 8147 21695 2 1448.796788 725.4024 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3914.2 - 1.71E+06 - - - 4.4879 - 3.109 0.502 - 842.4 1 2 0 0.0065 13 0 0 0 1.60E+08 1.04E+08 - - - 5.6579 1 230117_WJC_METTL3_WT_vs_EV_F01.21696.21696.2 0.000411 15/24 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.54 8148 21696 2 1438.784294 720.3983 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3914.3 - 1.57E+06 - - - 1.5833 - 3.108 0.479 - 845.5 1 2 0 0.0023 13 0 0 0 1.61E+08 1.04E+08 - - - 5.4886 1 230117_WJC_METTL3_WT_vs_EV_F01.21706.21706.2 2.90E-05 16-Sep R.FWYFVSQLK[136.11].K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1224.6423 0.74 8157 21706 2 1224.642553 613.3284 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3915.3 - 5.12E+06 - - - 0.2221 - 1.79 0.526 - 302 1 2 0 0.0003 9 0 0 0 5.76E+07 7.82E+07 - - - 4.6103 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21708.21708.2 5.11E-05 16-Sep R.FWYFVSQLK.K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1216.6281 0.74 8159 21708 2 1216.628193 609.3213 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3915.4 - 3.70E+06 - - - 0.0921 - 1.705 0.418 - 250.2 1 2 0 0.0001 9 0 0 0 5.76E+07 7.81E+07 - - - 3.6719 1 230117_WJC_METTL3_WT_vs_EV_F01.21710.21710.2 3.27E-07 13/20 K.LPDVYGVFQFK[136.11].V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1319.7005 1.17 8161 21710 2 1319.702085 660.8575 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.83 3915.6 - 2.78E+06 - - - 1.1828 - 2.337 0.559 - 637 1 2 0 0.0016 11 0 0 0 2.63E+07 2.25E+07 - - - 5.4657 0.999 230117_WJC_METTL3_WT_vs_EV_F01.21713.21713.2 0.000344 20-Sep K.NFGLIASYLER[166.11].K "sp|O75376|NCOR1_HUMAN,tr|E7EVU5|E7EVU5_HUMAN,tr|J3KS51|J3KS51_HUMAN,tr|E7EW50|E7EW50_HUMAN,tr|A0A088AWL3|A0A088AWL3_HUMAN" 5 1291.68 1.7 8164 21713 2 1291.678625 646.8473 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 6 3915.9 - 838516 - - - -1.0699 - 2.042 0.376 - 279.9 1 2 0 -0.0014 11 0 0 0 7.01E+06 4.12E+06 - - - 3.7491 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.21715.21715.2 0.00226 16-Sep K.WPLSLIINR[166.11].K "sp|Q9BSJ2|GCP2_HUMAN,tr|F2Z2B9|F2Z2B9_HUMAN,tr|A0A804HL95|A0A804HL95_HUMAN,tr|A0A804HJ08|A0A804HJ08_HUMAN,tr|A0A804HJQ4|A0A804HJQ4_HUMAN,tr|A0A804HJS9|A0A804HJS9_HUMAN,tr|A0A804HI27|A0A804HI27_HUMAN" 7 1120.6632 1.77 8166 21715 2 1120.661695 561.3389 Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2 9.75 3916.2 - 690064 - - - -1.3742 - 1.759 0.39 - 194.1 1 2 0 -0.0015 9 0 0 0 5.39E+06 3.04E+06 - - - 3.5549 1 230117_WJC_METTL3_WT_vs_EV_F01.21719.21719.2 1.48E-06 16/26 K.VLLLSSPGLEELYR[166.11].C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1597.8955 1.07 8168 21719 2 1597.892877 799.955 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3916.8 - 3.49E+06 - - - -1.6284 - 2.981 0.448 - 802.2 1 2 0 -0.0026 14 0 0 0 3.51E+07 3.26E+07 - - - 5.0901 0.9945 230117_WJC_METTL3_WT_vs_EV_F01.21720.21720.2 0.0463 16-Aug K.YLDFVFAVK.N "sp|P13473|LAMP2_HUMAN,tr|H0YCG2|H0YCG2_HUMAN" 2 1100.5906 6.4 8169 21720 2 1100.589651 551.3026 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.83 3916.8 - 3.54E+06 - - - -0.8922 - 1.016 0.347 - 121.6 1 2 0 -0.001 9 0 0 0 1.71E+07 2.68E+06 - - - 1.6496 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.21722.21722.3 0.000708 Dec-48 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.61 8171 21722 3 1438.781898 480.6013 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3917.1 - 1.55E+06 - - - -0.082 - 2.661 0.381 - 238.6 1 2 0 -0.0001 13 0 0 0 1.33E+07 8.30E+06 - - - 5.4413 0.9935 230117_WJC_METTL3_WT_vs_EV_F01.21723.21723.2 0.00139 22-Sep R.LLFPAVDDNLLK[136.11].F "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1364.7795 1.8 8172 21723 2 1364.774404 683.397 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 4.21 3917.2 - 1.54E+06 - - - -3.7361 - 1.874 0.373 - 221.6 1 2 0 -0.0051 12 0 0 0 2.22E+07 1.24E+07 - - - 3.4469 0.9973 230117_WJC_METTL3_WT_vs_EV_F01.21725.21725.2 0.000369 22-Sep R.LNMGEIETLDDY.- "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1411.6177 - 8174 21725 2 1411.613732 706.8161 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 3.43 3917.5 - 1.24E+06 - - - -2.8195 - 1.832 0.463 - 217.3 1 2 0 -0.004 12 0 0 0 - - - - - 4.0524 0.9885 230117_WJC_METTL3_WT_vs_EV_F01.21729.21729.2 0.0149 14-Jul R.SVFLTFLR.M "sp|Q9H1I8|ASCC2_HUMAN,tr|B1AH59|B1AH59_HUMAN" 2 981.5648 16.85 8178 21729 2 981.561417 491.7897 Activating signal cointegrator 1 complex subunit 2 OS=Homo sapiens OX=9606 GN=ASCC2 PE=1 SV=3 9.47 3917.9 - 961678 - - - -3.3987 - 1.619 0.265 - 140.7 1 2 0 -0.0033 8 0 0 0 5.85E+06 3.47E+05 - - - 2.4504 1 230117_WJC_METTL3_WT_vs_EV_F01.21734.21734.2 4.28E-06 22-Nov R.YFPTQALNFAFK[136.11].D "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 1453.7485 1.09 8183 21734 2 1453.744419 727.8815 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.59 3918.6 - 718450 - - - -2.8327 - 2.051 0.501 - 401.2 1 2 0 -0.0041 12 0 0 0 6.49E+07 5.93E+07 - - - 4.6301 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.21742.21742.2 0.00518 14-Sep R.ILEFFGLK.K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 965.5586 1.7 8189 21742 2 965.558919 483.7866 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3919.5 - 2.02E+06 - - - 0.3252 - 1.693 0.348 - 203.9 1 2 0 0.0003 8 0 0 0 4.11E+07 2.42E+07 - - - 3.1991 1 230117_WJC_METTL3_WT_vs_EV_F01.21744.21744.2 7.99E-06 20-Dec K.AFVDFLSDEIK.E sp|Q07021|C1QBP_HUMAN 1 1282.6445 2.02 8191 21744 2 1282.642759 642.3295 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.03 3919.7 - 1.10E+06 - - - -1.3722 - 2.251 0.579 - 459.4 1 2 0 -0.0018 11 0 0 0 1.44E+07 7.14E+06 - - - 5.5119 0.9954 230117_WJC_METTL3_WT_vs_EV_F01.21745.21745.2 0.0883 16-Aug K.EVNLVLLLK.N "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1039.6641 999 8192 21745 2 1039.668923 520.8393 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 6.1 3919.9 - 993347 - - - 4.6082 - 1.724 0.26 - 287.3 1 2 0 0.0048 9 0 0 0 9.07E+06 0.00E+00 - - - 2.5355 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.21748.21748.2 0.0257 14-Sep K.LYDFYLFK.C sp|Q2TAL8|QRIC1_HUMAN 1 1107.5641 2.28 8195 21748 2 1107.566012 554.7893 Transcriptional regulator QRICH1 OS=Homo sapiens OX=9606 GN=QRICH1 PE=1 SV=1 5.83 3920.2 - 586876 - - - 1.7408 - 1.411 0.3 - 209 1 2 0 0.0019 8 0 0 0 7.48E+06 3.28E+06 - - - 2.2946 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.21751.21751.2 0.0263 16-Sep R.DDLLGFALR.E sp|Q9Y617|SERC_HUMAN 1 1018.5447 2.12 8198 21751 2 1018.544798 510.2796 Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1 PE=1 SV=2 4.21 3920.6 - 498336 - - - 0.052 - 1.74 0.277 - 226.6 1 2 0 0.0001 9 0 0 0 1.42E+07 6.68E+06 - - - 2.6893 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21753.21753.2 2.82 13/24 R.LGPLLLDPSLAVR[166.11].E sp|Q7Z4Q2|HEAT3_HUMAN 1 1372.8318 1.2 8200 21753 2 1372.83351 687.4232 HEAT repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=HEATR3 PE=1 SV=2 5.84 3920.9 - 432112 - - - 1.2769 - 2.308 0.288 - 483 1 2 0 0.0018 13 0 0 0 4.84E+06 4.03E+06 - - - 3.3142 1 230117_WJC_METTL3_WT_vs_EV_F01.21763.21763.2 1.21E-06 20-Nov K.AFVDFLSDEIK[136.11].E sp|Q07021|C1QBP_HUMAN 1 1290.6587 2.34 8209 21763 2 1290.65884 646.3366 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.03 3922.1 - 155646 - - - 0.0938 - 2.059 0.526 - 371.3 1 2 0 0.0001 11 0 0 0 1.67E+07 7.14E+06 - - - 4.8798 1 230117_WJC_METTL3_WT_vs_EV_F01.21767.21767.2 5.66E-05 22-Oct K.WLAPDGLIFPDR.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1398.7296 0.81 8213 21767 2 1398.73545 700.3721 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3922.2 - 493289 - - - 4.1924 - 2.15 0.558 - 366.2 1 2 0 0.0059 12 0 0 0 6.70E+07 8.24E+07 - - - 5.1746 0.9978 230117_WJC_METTL3_WT_vs_EV_F01.21773.21773.2 4.14E-06 26-Aug R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.13 8219 21773 2 1478.891077 740.4549 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3922.6 - 137691 - - - -2.7886 - 1.709 0.565 - 167.1 1 2 0 -0.0041 14 0 0 0 1.20E+08 1.07E+08 - - - 4.5576 1 230117_WJC_METTL3_WT_vs_EV_F01.21782.21782.2 4.91E-06 14/26 R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.13 8226 21782 2 1470.884482 736.4478 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3923.8 - 5.26E+06 - - - 2.3666 - 2.584 0.612 - 400.3 1 2 0 0.0035 14 0 0 0 1.20E+08 1.07E+08 - - - 5.9425 1 230117_WJC_METTL3_WT_vs_EV_F01.21783.21783.2 0.00191 18-Nov R.IQFFAIEIAR.N sp|Q9BVG4|PBDC1_HUMAN 1 1206.6761 4.05 8227 21783 2 1206.681071 604.3453 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 6 3923.9 - 1.70E+06 - - - 4.1246 - 2.272 0.464 - 391.2 1 2 0 0.005 10 0 0 0 5.07E+06 1.25E+06 - - - 4.7573 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.21784.21784.3 9.40E-05 17/52 R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.27 8228 21784 3 1478.899715 493.9723 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3924 - 1.06E+06 - - - 3.0523 - 2.152 0.468 - 350.5 1 2 0 0.0045 14 0 0 0 2.82E+07 2.23E+07 - - - 5.7932 1 230117_WJC_METTL3_WT_vs_EV_F01.21786.21786.3 9.39E-07 19/52 R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.27 8230 21786 3 1470.885848 491.3009 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3924.3 - 998038 - - - 3.2953 - 2.87 0.615 - 364.3 1 2 0 0.0048 14 0 0 0 2.82E+07 2.23E+07 - - - 8.1972 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.21787.21787.2 0.00211 22-Oct R.FSPIPFPPLSYK.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1391.7489 16.35 8231 21787 2 1391.753858 696.8817 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3924.4 - 837412 - - - 3.5445 - 1.828 0.331 - 190.1 1 2 0 0.0049 12 0 0 0 1.00E+07 6.14E+05 - - - 3.0714 1 230117_WJC_METTL3_WT_vs_EV_F01.21793.21793.2 1.44E-05 15/28 R.ELALALQEALEPAVR.L sp|Q5RKV6|EXOS6_HUMAN 1 1621.9039 0.88 8237 21793 2 1621.90858 811.9592 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 4.25 3925.2 - 506103 - - - 2.8719 - 3.23 0.447 - 857.2 1 2 0 0.0047 15 0 0 0 2.14E+06 2.43E+06 - - - 5.2237 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21796.21796.3 0.000818 14/56 R.ELALALQEALEPAVR.L sp|Q5RKV6|EXOS6_HUMAN 1 1621.9039 1.22 8240 21796 3 1621.910997 541.6419 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 4.25 3925.6 - 469363 - - - 4.3622 - 2.618 0.386 - 205.4 1 2 0 0.0071 15 0 0 0 1.75E+06 1.43E+06 - - - 5.3528 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.21798.21798.2 0.0003 18-Oct R.SLGPVELLLR[166.11].G "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1105.6735 2.62 8242 21798 2 1105.676851 553.844 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.72 3925.8 - 375971 - - - 3.0624 - 1.957 0.439 - 299.1 1 2 0 0.0034 10 0 0 0 5.90E+06 2.25E+06 - - - 4.1565 0.9777 230117_WJC_METTL3_WT_vs_EV_F01.21799.21799.2 1.27 18-Jun K.LVLLGVDLSK[136.11].L "sp|Q96E29|MTEF3_HUMAN,tr|E5RIK9|E5RIK9_HUMAN" 2 1063.6732 -1 8243 21799 2 1063.675924 532.8439 "Transcription termination factor 3, mitochondrial OS=Homo sapiens OX=9606 GN=MTERF3 PE=1 SV=2" 5.84 3926 - 355120 - - - 2.5168 - 0.981 0.157 - 38 1 2 0 0.0027 10 0 0 0 0.00E+00 0.00E+00 - - - 0.1462 0.9748 230117_WJC_METTL3_WT_vs_EV_F01.21802.21802.2 0.845 16-Jun R.FYELLVTGR.Y "sp|Q9UPS6|SET1B_HUMAN,tr|A0A0A0MQV9|A0A0A0MQV9_HUMAN" 2 1096.5917 9.39 8245 21802 2 1096.595893 549.3031 Histone-lysine N-methyltransferase SETD1B OS=Homo sapiens OX=9606 GN=SETD1B PE=1 SV=3 6 3926.3 - 315212 - - - 3.8273 - 1.233 0.149 - 113.1 2 2 0 0.0042 9 0 0 0 9.25E+06 9.85E+05 - - - 0.6117 0.9975 230117_WJC_METTL3_WT_vs_EV_F01.21805.21805.2 0.243 14-Jul R.SWLLPVIR[166.11].D sp|Q5JTH9|RRP12_HUMAN 1 992.6047 1.43 8248 21805 2 992.604332 497.3096 RRP12-like protein OS=Homo sapiens OX=9606 GN=RRP12 PE=1 SV=2 9.47 3926.5 - 321840 - - - -0.3274 - 1.626 0.208 - 276.8 1 2 0 -0.0003 8 0 0 0 6.19E+06 4.32E+06 - - - 2.0433 1 230117_WJC_METTL3_WT_vs_EV_F01.21806.21806.2 1.10E-07 13/26 K.TYVLNPLAPEFIPR.A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1628.8926 2.87 8249 21806 2 1628.894125 815.4536 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.66 3926.7 - 157233 - - - 0.9184 - 2.493 0.583 - 491.9 1 2 0 0.0015 14 0 0 0 5.86E+06 2.04E+06 - - - 5.6389 1 230117_WJC_METTL3_WT_vs_EV_F01.21807.21807.2 2.09E-11 16/30 K.LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1793.9075 0.9 8250 21807 2 1793.909256 897.961 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3926.7 - 116709 - - - 0.9789 - 3.075 0.626 - 671 1 2 0 0.0018 16 0 0 0 2.76E+07 3.08E+07 - - - 6.4258 1 230117_WJC_METTL3_WT_vs_EV_F01.21817.21817.2 2.43E-05 18/30 K.LFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1783.8992 0.9 8258 21817 2 1783.898604 892.9569 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3928 - 7.49E+06 - - - -0.3509 - 3.183 0.58 - 920.2 1 2 0 -0.0006 16 0 0 0 2.76E+07 3.08E+07 - - - 6.1712 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.21818.21818.2 9.30E-05 13/18 R.VVTDLISLIR.Q sp|P38432|COIL_HUMAN 1 1127.6914 1.1 8259 21818 2 1127.690548 564.853 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3928.1 - 4.03E+06 - - - -0.7644 - 2.209 0.37 - 627.2 1 2 0 -0.0009 10 0 0 0 1.04E+07 9.44E+06 - - - 3.9858 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21819.21819.2 0.000348 13/18 R.VVTDLISLIR[166.11].Q sp|P38432|COIL_HUMAN 1 1137.6997 1.1 8260 21819 2 1137.701185 569.8571 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3928.2 - 3.98E+06 - - - 1.3228 - 2.253 0.419 - 611.5 1 2 0 0.0015 10 0 0 0 1.04E+07 9.44E+06 - - - 4.4025 1 230117_WJC_METTL3_WT_vs_EV_F01.21822.21822.3 1.73E-07 19/60 K.LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1793.9075 0.95 8263 21822 3 1793.912264 598.9764 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3928.6 - 2.32E+06 - - - 2.6557 - 3.199 0.598 - 468.7 1 2 0 0.0048 16 0 0 0 4.82E+06 5.09E+06 - - - 8.1895 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.21824.21824.3 0.000441 Nov-60 K.LFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1783.8992 -1 8265 21824 3 1783.902369 595.6404 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3928.8 - 1.86E+06 - - - 1.7596 - 2.463 0.459 - 128.7 1 2 0 0.0031 16 0 0 0 0.00E+00 0.00E+00 - - - 5.9693 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.21825.21825.2 0.000335 13/22 R.EMLAVSVLAAVR[166.11].G sp|Q9NX62|IMPA3_HUMAN 1 1267.7198 -1 8266 21825 2 1267.720713 634.8672 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 6.1 3928.9 - 6.01E+06 - - - 0.7494 - 1.76 0.347 - 298.5 1 2 0 0.0009 12 0 0 0 0.00E+00 0.00E+00 - - - 3.0911 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21826.21826.2 0.0019 18-Oct R.DAVLLLFANK.Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1102.6386 2.16 8267 21826 2 1102.640685 552.3266 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3929 - 1.32E+06 - - - 1.8492 - 2.178 0.395 - 450.5 1 2 0 0.002 10 0 0 0 2.13E+07 9.84E+06 - - - 4.1306 0.9646 230117_WJC_METTL3_WT_vs_EV_F01.21828.21828.3 0.000407 21/72 K.LLHHLSDLALTLPTDAVSI.C "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2028.1255 - 8269 21828 3 2028.13172 677.0491 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.05 3929.3 - 1.18E+06 - - - 3.0462 - 3.083 0.433 - 451.5 1 1 0 0.0062 19 0 0 0 - - - - - 6.1319 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.21829.21829.3 0.00654 Nov-44 K.WLAPDGLIFPDR[166.11].A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1408.7379 0.8 8270 21829 3 1408.740114 470.5866 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3929.4 - 1.05E+06 - - - 1.6029 - 2.181 0.364 - 146.6 1 2 0 0.0023 12 0 0 0 2.36E+06 2.96E+06 - - - 4.7591 1 230117_WJC_METTL3_WT_vs_EV_F01.21833.21833.2 8.17E-05 20-Oct K.LDTSQWPLLLK[136.11].N "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1320.7533 0.63 8274 21833 2 1320.756793 661.3839 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 5.84 3929.9 - 1.01E+06 - - - 2.6538 - 2.433 0.491 - 431.4 1 2 0 0.0035 11 0 0 0 2.39E+06 3.76E+06 - - - 5.0717 1 230117_WJC_METTL3_WT_vs_EV_F01.21834.21834.2 1.10E-05 20-Nov R.FLEEFITPIVK[136.11].V "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 1342.7628 -1 8275 21834 2 1342.765115 672.3887 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.53 3930.1 - 980377 - - - 1.7315 - 2.152 0.495 - 329.8 1 2 0 0.0023 11 0 0 0 0.00E+00 0.00E+00 - - - 4.7696 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.21836.21836.3 0.0125 14/52 K.TYVLNPLAPEFIPR.A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1628.8926 0.94 8277 21836 3 1628.896887 543.9715 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.66 3930.3 - 958390 - - - 2.614 - 2.193 0.266 - 231.9 1 2 0 0.0043 14 0 0 0 2.74E+06 2.92E+06 - - - 3.5913 1 230117_WJC_METTL3_WT_vs_EV_F01.21841.21841.2 0.00187 18-Dec R.DAVLLLFANK[136.11].Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1110.6528 2.19 8281 21841 2 1110.652768 556.3337 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3930.9 - 2.32E+06 - - - -0.0702 - 2.676 0.514 - 758.5 1 2 0 -0.0001 10 0 0 0 2.18E+07 9.96E+06 - - - 5.5849 1 230117_WJC_METTL3_WT_vs_EV_F01.21843.21843.2 0.00115 20-Nov R.LFEFAGYDVLR[166.11].L sp|P54136|SYRC_HUMAN 1 1338.6848 -1 8283 21843 2 1338.685898 670.3497 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3931 - 1.14E+06 - - - 0.8516 - 2.362 0.463 - 423.9 1 2 0 0.0011 11 0 0 0 0.00E+00 0.00E+00 - - - 4.7855 0.9566 230117_WJC_METTL3_WT_vs_EV_F01.21844.21844.2 0.0305 16-Sep N.VLIIGELLK.Q "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 996.6583 26.66 8284 21844 2 996.658587 499.3364 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.97 3931.1 - 1.11E+06 - - - 0.2689 - 1.796 0.361 - 244.5 1 1 0 0.0003 9 0 0 0 4.46E+06 1.67E+05 - - - 3.4013 0.9962 230117_WJC_METTL3_WT_vs_EV_F01.21847.21847.2 0.0199 16-Jul R.GYPTLLLFR.G sp|Q8NBS9|TXND5_HUMAN 1 1078.6175 1.57 8287 21847 2 1078.615564 540.316 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 8.75 3931.3 - 812771 - - - -1.8097 - 1.55 0.306 - 215.7 1 2 0 -0.002 9 0 0 0 1.42E+07 9.04E+06 - - - 2.5684 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21848.21848.2 0.00155 18-Nov R.DALLLIFANK.Q "sp|P36406|TRI23_HUMAN,sp|P62330|ARF6_HUMAN" 2 1116.6543 1.68 8288 21848 2 1116.654389 559.3344 E3 ubiquitin-protein ligase TRIM23 OS=Homo sapiens OX=9606 GN=TRIM23 PE=1 SV=1 5.84 3931.4 - 780810 - - - 0.0833 - 2.452 0.396 - 385.1 1 2 0 0.0001 10 0 0 0 1.64E+07 9.79E+06 - - - 4.4694 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21854.21854.2 0.000355 22-Sep R.DYVFYLAVGNYR[166.11].L sp|Q9Y3D6|FIS1_HUMAN 1 1488.7277 -1 8294 21854 2 1488.730178 745.3711 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 5.83 3932 - 254964 - - - 1.6746 - 1.925 0.447 - 305.5 1 2 0 0.0025 12 0 0 0 0.00E+00 0.00E+00 - - - 4.065 1 230117_WJC_METTL3_WT_vs_EV_F01.21862.21862.2 3.12E-09 14/30 R.IIGATDSSGELMFLMK.W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1711.8525 1.3 8301 21862 2 1711.853527 856.9335 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3932.9 - 4.14E+06 - - - 0.6116 - 3.14 0.619 - 382.1 1 2 0 0.001 16 0 0 0 2.20E+07 1.69E+07 - - - 6.4257 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.21865.21865.2 0.00678 18-Sep R.GLIPVFALGR.A "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1041.6335 3.01 8304 21865 2 1041.63345 521.824 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 9.75 3933 - 2.53E+06 - - - -0.049 - 1.652 0.271 - 229 1 2 0 -0.0001 10 0 0 0 6.83E+06 2.27E+06 - - - 2.4438 1 230117_WJC_METTL3_WT_vs_EV_F01.21866.21866.2 1.68E-05 16-Oct K.APWELLELR[166.11].V "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A6Q8PF15|A0A6Q8PF15_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN,tr|A0A6Q8PFC1|A0A6Q8PFC1_HUMAN" 6 1135.6265 0.69 8305 21866 2 1135.624468 568.8205 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.53 3933.1 - 2.42E+06 - - - -1.8025 - 1.973 0.489 - 507.2 1 2 0 -0.002 9 0 0 0 4.83E+06 6.96E+06 - - - 4.6181 1 230117_WJC_METTL3_WT_vs_EV_F01.21867.21867.2 0.00369 13/20 K.VTDLLGGLFSK[136.11].T "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1156.6583 2.34 8306 21867 2 1156.658382 579.3364 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.81 3933.1 - 2.26E+06 - - - 0.0493 - 2.813 0.45 - 910.2 1 2 0 0.0001 11 0 0 0 8.34E+07 3.57E+07 - - - 5.1626 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21871.21871.2 0.0145 18-Aug R.GLIPVFALGR[166.11].A "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1051.6418 -1 8310 21871 2 1051.642985 526.8282 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 9.75 3933.4 - 1.30E+06 - - - 1.1544 - 1.61 0.383 - 121.2 1 2 0 0.0012 10 0 0 0 0.00E+00 0.00E+00 - - - 3.1988 1 230117_WJC_METTL3_WT_vs_EV_F01.21874.21874.2 3.68E-07 26-Dec R.ILLDIDNDTESTAL.- sp|Q68EM7|RHG17_HUMAN 1 1531.7617 - 8313 21874 2 1531.762272 766.8881 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 3.37 3933.7 - 928939 - - - 0.3512 - 2.378 0.507 - 362.8 1 2 0 0.0005 14 0 0 0 - - - - - 4.9594 1 230117_WJC_METTL3_WT_vs_EV_F01.21880.21880.2 9.21E-09 14/30 R.IIGATDSSGELMFLMK[136.11].W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1719.8667 1.3 8318 21880 2 1719.866063 860.9406 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3934.3 - 3.62E+06 - - - -0.3587 - 2.848 0.606 - 387.9 1 2 0 -0.0006 16 0 0 0 2.20E+07 1.69E+07 - - - 6.0899 1 230117_WJC_METTL3_WT_vs_EV_F01.21885.21885.2 2.60E-08 14/24 K.SVDPTLALSVYLR[166.11].A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1442.8009 1.04 8323 21885 2 1442.801518 722.4077 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.55 3934.6 - 2.65E+06 - - - 0.463 - 2.809 0.614 - 625.5 1 2 0 0.0007 13 0 0 0 1.54E+07 1.47E+07 - - - 6.2266 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21887.21887.2 0.0897 18-Oct R.DALLLIFANK[136.11].Q "sp|P36406|TRI23_HUMAN,sp|P62330|ARF6_HUMAN" 2 1124.6685 1.68 8325 21887 2 1124.669217 563.3415 E3 ubiquitin-protein ligase TRIM23 OS=Homo sapiens OX=9606 GN=TRIM23 PE=1 SV=1 5.84 3934.8 - 2.18E+06 - - - 0.6411 - 2.162 0.314 - 256.6 1 2 0 0.0007 10 0 0 0 1.64E+07 9.79E+06 - - - 3.5122 0.9812 230117_WJC_METTL3_WT_vs_EV_F01.21891.21891.3 0.0547 Dec-40 K.IRFLILPDMLK.N sp|P62318|SMD3_HUMAN 1 1357.8156 1.4 8329 21891 3 1357.81469 453.6125 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 8.75 3935.1 - 946270 - - - -0.6437 - 2.656 0.345 - 327.8 1 2 1 -0.0009 11 0 0 0 3.02E+06 2.16E+06 - - - 5.1612 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.21892.21892.2 6.60E-05 20-Dec K.LDTSQWPLLLK.N "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1312.7391 0.96 8330 21892 2 1312.743707 657.3768 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 5.84 3935.2 - 945411 - - - 3.5186 - 2.163 0.426 - 479 1 2 0 0.0046 11 0 0 0 8.50E+06 8.89E+06 - - - 4.2731 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.21893.21893.2 0.0331 16-Sep R.LVTLEEFLK.A "sp|P80303|NUCB2_HUMAN,tr|H0YD18|H0YD18_HUMAN,tr|E9PKG6|E9PKG6_HUMAN" 3 1090.6274 1.71 8331 21893 2 1090.626446 546.321 Nucleobindin-2 OS=Homo sapiens OX=9606 GN=NUCB2 PE=1 SV=3 4.53 3935.3 - 822935 - - - -0.8857 - 1.906 0.286 - 189.7 1 2 0 -0.001 9 0 0 0 4.21E+06 2.46E+06 - - - 3.0191 1 230117_WJC_METTL3_WT_vs_EV_F01.21902.21902.2 3.35E-11 18/30 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 0.95 8338 21902 2 1807.923541 904.9689 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3936.3 - 1.59E+07 - - - 0.2163 - 3.507 0.627 - 1042 1 2 0 0.0004 16 0 0 0 1.32E+08 1.40E+08 - - - 6.7568 1 230117_WJC_METTL3_WT_vs_EV_F01.21903.21903.2 3.90E-10 18/30 K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 0.95 8339 21903 2 1797.9162 899.9647 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3936.4 - 1.46E+07 - - - 0.7342 - 3.5 0.648 - 966.7 1 2 0 0.0013 16 0 0 0 1.32E+08 1.40E+08 - - - 6.9067 1 230117_WJC_METTL3_WT_vs_EV_F01.21905.21905.3 2.92E-07 15/60 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 0.91 8341 21905 3 1807.925583 603.6483 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3936.5 - 5.40E+06 - - - 1.3457 - 2.771 0.543 - 315.2 1 2 0 0.0024 16 0 0 0 2.90E+07 3.19E+07 - - - 7.2084 1 230117_WJC_METTL3_WT_vs_EV_F01.21906.21906.2 2.77E-07 20-Dec K.YPSPFFVFGEK.L sp|Q08211|DHX9_HUMAN 1 1316.6441 0.97 8342 21906 2 1316.645365 659.3293 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3936.5 - 4.67E+06 - - - 0.9418 - 2.403 0.589 - 599.6 1 2 0 0.0012 11 0 0 0 1.73E+08 1.79E+08 - - - 5.7627 1 230117_WJC_METTL3_WT_vs_EV_F01.21907.21907.2 1.86E-05 20-Oct R.VINQMLEFAFR.Y "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 1366.7067 -1 8343 21907 2 1366.708736 684.3606 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 5.97 3936.6 - 3.86E+06 - - - 1.459 - 2.37 0.446 - 304.9 1 2 0 0.002 11 0 0 0 0.00E+00 0.00E+00 - - - 4.6689 1 230117_WJC_METTL3_WT_vs_EV_F01.21909.21909.2 8.51E-09 22-Dec R.FSTFFDDAPVFR.L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1447.6772 -1 8345 21909 2 1447.679442 724.8459 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3936.7 - 2.53E+06 - - - 1.5376 - 2.289 0.589 - 444.6 1 2 0 0.0022 12 0 0 0 0.00E+00 0.00E+00 - - - 5.5696 1 230117_WJC_METTL3_WT_vs_EV_F01.21910.21910.2 8.17E-07 14/20 R.VINQMLEFAFR[166.11].Y "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 1376.715 -1 8346 21910 2 1376.716724 689.3648 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 5.97 3936.8 - 2.42E+06 - - - 1.2435 - 2.614 0.539 - 828.3 1 2 0 0.0017 11 0 0 0 0.00E+00 0.00E+00 - - - 5.6209 1 230117_WJC_METTL3_WT_vs_EV_F01.21912.21912.2 1.28E-05 18/24 K.TPFLLVGTQIDLR.D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1471.8399 1.41 8348 21912 2 1471.837932 736.9272 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3937 - 2.12E+06 - - - -1.3133 - 3.069 0.559 - 1324.8 1 2 0 -0.0019 13 0 0 0 2.92E+07 2.08E+07 - - - 6.0471 1 230117_WJC_METTL3_WT_vs_EV_F01.21913.21913.2 0.000929 18-Dec K.AWLLSMIQSK[136.11].C "sp|Q9UBU9|NXF1_HUMAN,tr|E9PLA7|E9PLA7_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1183.6515 0.88 8349 21913 2 1183.650186 592.833 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 8.8 3937.1 - 1.79E+06 - - - -1.0814 - 2.42 0.462 - 534.5 1 2 0 -0.0013 10 0 0 0 6.54E+06 7.42E+06 - - - 4.9198 1 230117_WJC_METTL3_WT_vs_EV_F01.21914.21914.2 6.60E-06 13/22 R.FSTFFDDAPVFR[166.11].L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1457.6855 -1 8350 21914 2 1457.686337 729.85 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3937.1 - 1.55E+06 - - - 0.5838 - 2.435 0.546 - 503.3 1 2 0 0.0009 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4151 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.21915.21915.3 3.04E-05 Nov-40 R.SVVTVIDVFYK.Y sp|Q5D862|FILA2_HUMAN 1 1268.7016 -1 8351 21915 3 1268.701389 423.9078 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 5.55 3937.3 - 1.51E+06 - - - -0.1978 - 2.394 0.422 - 202.6 1 2 0 -0.0003 11 0 0 0 0.00E+00 0.00E+00 - - - 5.7248 1 230117_WJC_METTL3_WT_vs_EV_F01.21918.21918.2 4.01E-06 28-Nov K.ELLFLSNANPSLLER[166.11].H "sp|P51398|RT29_HUMAN,tr|V9GYF7|V9GYF7_HUMAN,tr|V9GYA7|V9GYA7_HUMAN,tr|V9GYW1|V9GYW1_HUMAN,tr|V9GZ61|V9GZ61_HUMAN" 5 1724.9337 -1 8354 21918 2 1724.942207 863.4741 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 4.53 3937.7 - 743326 - - - 4.9573 - 2.355 0.482 - 347.5 1 2 0 0.0086 15 0 0 0 0.00E+00 0.00E+00 - - - 4.7042 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.21919.21919.2 0.0148 28-Dec R.FALQLGDPSTGLLIR[166.11].A "sp|Q86TN4|TRPT1_HUMAN,tr|F5H6B6|F5H6B6_HUMAN,tr|F5H8A0|F5H8A0_HUMAN" 3 1609.9067 -1 8355 21919 2 1609.911813 805.9606 tRNA 2'-phosphotransferase 1 OS=Homo sapiens OX=9606 GN=TRPT1 PE=1 SV=2 5.84 3937.8 - 704210 - - - 3.1685 - 2.31 0.343 - 307.9 1 2 0 0.0051 15 0 0 0 0.00E+00 0.00E+00 - - - 3.6312 0.9434 230117_WJC_METTL3_WT_vs_EV_F01.21920.21920.2 1.48 22-Sep K.LNTLETEEWFFK[136.11].D "sp|P07948|LYN_HUMAN,tr|E5RJ37|E5RJ37_HUMAN" 2 1563.7701 0.89 8356 21920 2 1563.766183 782.8923 Tyrosine-protein kinase Lyn OS=Homo sapiens OX=9606 GN=LYN PE=1 SV=3 4.25 3937.9 - 472834 - - - -2.4799 - 1.214 0.14 - 130.1 1 2 0 -0.0039 12 0 0 0 3.89E+06 4.35E+06 - - - 0.5841 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.21921.21921.2 0.0681 14-Aug R.AAFLNFFR[166.11].D sp|Q5JTZ9|SYAM_HUMAN 1 994.5264 2.15 8357 21921 2 994.52654 498.2705 "Alanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=AARS2 PE=1 SV=1" 9.79 3938.1 - 396191 - - - 0.1337 - 1.548 0.34 - 202.5 1 2 0 0.0001 8 0 0 0 5.50E+06 2.56E+06 - - - 2.8701 1 230117_WJC_METTL3_WT_vs_EV_F01.21924.21924.2 0.00984 20-Nov K.YPSPFFVFGEK[136.11].L sp|Q08211|DHX9_HUMAN 1 1324.6583 0.97 8358 21924 2 1324.65839 663.3364 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3938.4 - 1.86E+07 - - - 0.0491 - 2.246 0.504 - 529.1 1 2 0 0.0001 11 0 0 0 1.73E+08 1.79E+08 - - - 4.9525 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.21926.21926.2 0.0106 14-Jul R.GFGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 921.5204 1.09 8360 21926 2 921.520185 461.7675 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3938.5 - 1.35E+07 - - - -0.2062 - 1.372 0.466 - 146.6 1 2 0 -0.0002 8 0 0 0 7.10E+08 6.51E+08 - - - 3.4367 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.21927.21927.2 0.000416 14-Aug R.GFGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 913.5062 1.09 8361 21927 2 913.50598 457.7604 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3938.6 - 1.09E+07 - - - -0.2135 - 1.466 0.456 - 207.2 1 2 0 -0.0002 8 0 0 0 7.10E+08 6.51E+08 - - - 3.5627 1 230117_WJC_METTL3_WT_vs_EV_F01.21928.21928.2 8.64E-05 20-Oct R.ASILNTWISLK.Q "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN" 2 1244.7129 1.57 8362 21928 2 1244.713952 623.3637 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 8.8 3938.6 - 7.19E+06 - - - 0.8669 - 2.363 0.477 - 211.3 1 2 0 0.0011 11 0 0 0 3.52E+07 2.24E+07 - - - 4.8901 1 230117_WJC_METTL3_WT_vs_EV_F01.21929.21929.2 0.000632 13/24 N.IVGLVGVDQFLVK.T sp|P13639|EF2_HUMAN 1 1385.8282 -1 8363 21929 2 1385.828887 693.9214 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3938.7 - 6.22E+06 - - - 0.4683 - 2.733 0.496 - 499.6 1 1 0 0.0006 13 0 0 0 0.00E+00 0.00E+00 - - - 5.2846 1 230117_WJC_METTL3_WT_vs_EV_F01.21930.21930.2 3.86E-05 14/24 K.TPFLLVGTQIDLR[166.11].D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1481.8481 1.41 8364 21930 2 1481.847926 741.9313 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3938.7 - 5.42E+06 - - - -0.141 - 3.093 0.579 - 754.8 1 2 0 -0.0002 13 0 0 0 2.92E+07 2.08E+07 - - - 6.2154 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.21931.21931.2 7.24E-05 20-Nov R.ASILNTWISLK[136.11].Q "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN" 2 1252.7271 1.57 8365 21931 2 1252.729968 627.3708 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 8.8 3938.7 - 4.27E+06 - - - 2.311 - 2.255 0.42 - 460.4 1 2 0 0.0029 11 0 0 0 3.52E+07 2.25E+07 - - - 4.342 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.21932.21932.2 0.000475 16-Oct K.GVIDLIFEK.A "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 1032.5855 1.88 8366 21932 2 1032.585491 517.3001 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 3938.8 - 3.45E+06 - - - -0.0552 - 1.783 0.379 - 243.1 1 2 0 -0.0001 9 0 0 0 1.29E+07 6.86E+06 - - - 3.5133 1 230117_WJC_METTL3_WT_vs_EV_F01.21934.21934.2 0.000854 13/24 N.IVGLVGVDQFLVK[136.11].T sp|P13639|EF2_HUMAN 1 1393.8424 -1 8368 21934 2 1393.842595 697.9285 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3938.9 - 2.68E+06 - - - 0.1126 - 2.424 0.479 - 463.9 1 1 0 0.0002 13 0 0 0 0.00E+00 0.00E+00 - - - 4.8513 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.21935.21935.2 0.0139 20-Sep R.IFGLLMGTLQK[136.11].F sp|Q9H307|PININ_HUMAN 1 1227.7141 1.09 8369 21935 2 1227.713705 614.8643 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3939 - 2.51E+06 - - - -0.294 - 1.955 0.344 - 183.9 1 2 0 -0.0004 11 0 0 0 8.70E+07 7.96E+07 - - - 3.3952 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.21936.21936.3 0.000157 Dec-48 K.TPFLLVGTQIDLR.D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1471.8399 1.45 8370 21936 3 1471.840076 491.6206 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3939 - 2.49E+06 - - - 0.1434 - 2.375 0.433 - 209.3 1 2 0 0.0002 13 0 0 0 8.35E+06 5.77E+06 - - - 5.7127 1 230117_WJC_METTL3_WT_vs_EV_F01.21938.21938.2 0.000133 14/22 K.VPGLYVIDSIVR.Q "sp|O95104|SCAF4_HUMAN,sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 3 1329.7656 1.56 8372 21938 2 1329.767065 665.8901 SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3 5.81 3939.2 - 2.09E+06 - - - 1.0739 - 2.545 0.453 - 832.5 1 2 0 0.0014 12 0 0 0 1.24E+07 7.91E+06 - - - 4.8443 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.21940.21940.2 0.00839 16-Oct K.LLELDSFLK.E "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|K9J957|K9J957_HUMAN,tr|B7Z8D3|B7Z8D3_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 5 1076.6118 1.21 8374 21940 2 1076.61274 539.3132 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.37 3939.4 - 1.92E+06 - - - 0.9084 - 1.83 0.261 - 208 1 2 0 0.001 9 0 0 0 1.63E+07 1.36E+07 - - - 2.7168 1 230117_WJC_METTL3_WT_vs_EV_F01.21941.21941.2 7.18E-06 13/22 K.VPGLYVIDSIVR[166.11].Q "sp|O95104|SCAF4_HUMAN,sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 3 1339.7739 1.56 8375 21941 2 1339.773122 670.8942 SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3 5.81 3939.5 - 1.81E+06 - - - -0.5859 - 2.53 0.508 - 786.9 1 2 0 -0.0008 12 0 0 0 1.24E+07 7.91E+06 - - - 5.2351 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.21945.21945.3 0.000282 Nov-48 K.TPFLLVGTQIDLR[166.11].D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1481.8481 1.45 8378 21945 3 1481.849432 494.9567 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3939.8 - 405013 - - - 0.8753 - 2.338 0.355 - 160.7 1 2 0 0.0013 13 0 0 0 8.35E+06 5.77E+06 - - - 4.8002 1 230117_WJC_METTL3_WT_vs_EV_F01.21946.21946.2 2.14E-05 30-Dec K.LFIGGLSFETTDDSLR[166.11].E "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1779.8918 0.45 8379 21946 2 1779.892394 890.9532 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.03 3939.9 - 470732 - - - 0.3056 - 2.519 0.536 - 357.8 1 2 0 0.0005 16 0 0 0 3.02E+06 6.71E+06 - - - 5.2711 1 230117_WJC_METTL3_WT_vs_EV_F01.21947.21947.3 1.93E-07 13/60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 71.45 8380 21947 3 1796.004662 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3940 - 2.85E+07 - - - 0.1659 - 2.683 0.527 - 297.2 1 2 0 0.0003 16 0 0 0 1.64E+08 2.29E+06 - - - 6.9478 1 230117_WJC_METTL3_WT_vs_EV_F01.21948.21948.2 0.000466 20-Dec R.IFGLLMGTLQK.F sp|Q9H307|PININ_HUMAN 1 1219.6999 1.09 8381 21948 2 1219.69986 610.8572 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3940 - 1.48E+07 - - - -0.0049 - 2.372 0.486 - 456.9 1 2 0 0 11 0 0 0 8.70E+07 7.96E+07 - - - 4.9672 1 230117_WJC_METTL3_WT_vs_EV_F01.21950.21950.2 2.49E-08 18/30 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 999 8383 21950 2 1796.004503 899.0095 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3940.1 - 5.99E+06 - - - 0.0774 - 3.791 0.645 - 1234.8 1 2 0 0.0001 16 0 0 0 4.09E+07 0.00E+00 - - - 7.0813 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21953.21953.2 0.0067 18-Nov K.FLLLQGLVEK[136.11].E "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 1166.7154 0.9 8386 21953 2 1166.715422 584.365 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 6 3940.2 - 4.27E+06 - - - -0.0206 - 2.112 0.386 - 423.8 1 2 0 0 10 0 0 0 1.48E+07 1.65E+07 - - - 3.9789 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.21954.21954.2 0.879 20-Dec K.LALGIPLPELR.N "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1190.7387 2.12 8387 21954 2 1190.739099 596.3766 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3940.3 - 4.09E+06 - - - 0.3401 - 2.562 0.261 - 403 1 2 0 0.0004 11 0 0 0 4.48E+07 2.11E+07 - - - 3.5137 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.21956.21956.2 0.0355 13/18 K.FLLLQGLVEK.E "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 1158.7012 0.9 8389 21956 2 1158.69857 580.3579 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 6 3940.4 - 2.94E+06 - - - -2.3095 - 2.391 0.377 - 624.5 1 2 0 -0.0027 10 0 0 0 1.48E+07 1.65E+07 - - - 4.2579 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21957.21957.2 0.000437 18-Nov K.IATLISSFLK.E "sp|O95394|AGM1_HUMAN,tr|A0A494C1E2|A0A494C1E2_HUMAN,tr|J3KN95|J3KN95_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C1Q4|A0A494C1Q4_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|A0A087WT27|A0A087WT27_HUMAN" 7 1091.659 2.44 8390 21957 2 1091.659174 546.8368 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 8.75 3940.4 - 2.57E+06 - - - 0.1163 - 2.361 0.373 - 290.7 1 2 0 0.0001 10 0 0 0 6.84E+06 2.80E+06 - - - 4.1939 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.21958.21958.2 6.84E-05 18-Aug K.SLESFVELMK.T sp|Q6KB66|K2C80_HUMAN 1 1181.6002 30.57 8391 21958 2 1181.60037 591.8074 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 4.53 3940.5 - 2.25E+06 - - - 0.1346 - 1.829 0.477 - 151.1 1 2 0 0.0002 10 0 0 0 6.13E+06 2.01E+05 - - - 4.2494 1 230117_WJC_METTL3_WT_vs_EV_F01.21960.21960.2 1.02E-06 14/24 K.WAIAQLNYADMLK.R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1535.7806 1.18 8393 21960 2 1535.776715 768.8976 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.83 3940.6 - 1.46E+06 - - - -2.5524 - 2.815 0.494 - 595.4 1 2 0 -0.0039 13 0 0 0 4.60E+06 3.91E+06 - - - 5.3447 0.9611 230117_WJC_METTL3_WT_vs_EV_F01.21961.21961.2 0.00791 12-Aug G.FGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 856.4847 1.18 8394 21961 2 856.484497 429.2496 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3940.8 - 1.43E+06 - - - -0.2499 - 1.807 0.434 - 178.6 1 1 0 -0.0002 7 0 0 0 6.71E+06 5.70E+06 - - - 4.1212 1 230117_WJC_METTL3_WT_vs_EV_F01.21962.21962.2 0.000255 12-Sep G.FGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 864.4989 1.18 8395 21962 2 864.498989 433.2567 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3940.8 - 1.31E+06 - - - 0.0902 - 1.828 0.53 - 230 1 1 0 0.0001 7 0 0 0 6.71E+06 5.70E+06 - - - 4.8669 0.9948 230117_WJC_METTL3_WT_vs_EV_F01.21964.21964.2 0.000887 22-Nov K.YDNMAELFAVVK.T "sp|Q9UK41|VPS28_HUMAN,tr|E9PR04|E9PR04_HUMAN,tr|E9PQR7|E9PQR7_HUMAN,tr|E9PM90|E9PM90_HUMAN" 4 1398.6853 4.78 8397 21964 2 1398.682193 700.3499 Vacuolar protein sorting-associated protein 28 homolog OS=Homo sapiens OX=9606 GN=VPS28 PE=1 SV=1 4.37 3941 - 1.22E+06 - - - -2.2485 - 1.594 0.308 - 182 1 2 0 -0.0031 12 0 0 0 5.64E+06 1.18E+06 - - - 2.5417 0.996 230117_WJC_METTL3_WT_vs_EV_F01.21967.21967.2 0.497 18-Sep K.IATLISSFLK[136.11].E "sp|O95394|AGM1_HUMAN,tr|A0A494C1E2|A0A494C1E2_HUMAN,tr|J3KN95|J3KN95_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C1Q4|A0A494C1Q4_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|A0A087WT27|A0A087WT27_HUMAN" 7 1099.6732 2.69 8399 21967 2 1099.673562 550.8439 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 8.75 3941.3 - 941040 - - - 0.2864 - 1.362 0.195 - 141.5 1 2 0 0.0003 10 0 0 0 6.84E+06 2.54E+06 - - - 1.3436 1 230117_WJC_METTL3_WT_vs_EV_F01.21968.21968.2 1.12E-07 15/22 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 2640.46 8400 21968 2 1459.791293 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3941.4 - 2.29E+07 - - - -0.6528 - 3.105 0.594 - 1021.2 1 2 0 -0.001 12 0 0 0 1.15E+09 4.36E+05 - - - 6.4091 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.21969.21969.3 1.74E-06 15/44 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 216.38 8401 21969 3 1459.791075 487.6047 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3941.4 - 2.61E+06 - - - -0.8022 - 2.901 0.437 - 441.9 1 2 0 -0.0012 12 0 0 0 1.07E+08 4.97E+05 - - - 6.364 1 230117_WJC_METTL3_WT_vs_EV_F01.21972.21972.2 1.02E-05 18-Dec K.ADLTALFLPR[166.11].Q sp|Q13045|FLII_HUMAN 1 1125.6422 1.84 8404 21972 2 1125.642894 563.8284 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.88 3941.7 - 1.72E+06 - - - 0.6476 - 2.479 0.546 - 468.4 1 2 0 0.0007 10 0 0 0 2.02E+07 1.10E+07 - - - 5.6076 1 230117_WJC_METTL3_WT_vs_EV_F01.21973.21973.2 1.43E-06 15/22 K.ITVNEVELLVMK.A "sp|Q9UNM6|PSD13_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 2 1386.7792 1.39 8405 21973 2 1386.778633 694.3969 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 4.53 3941.7 - 1.54E+06 - - - -0.437 - 3.164 0.581 - 979.3 1 2 0 -0.0006 12 0 0 0 2.05E+07 1.48E+07 - - - 6.3628 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.21975.21975.2 0.00217 20-Sep K.LWALQDFSC[160.03]LK.T "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 1379.6908 -1 8407 21975 2 1379.688187 690.8527 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.83 3941.9 - 1.41E+06 - - - -1.8635 - 1.972 0.442 - 326 1 2 0 -0.0026 11 0 0 0 0.00E+00 0.00E+00 - - - 4.1418 1 230117_WJC_METTL3_WT_vs_EV_F01.21985.21985.2 8.73E-06 13/22 K.ITVNEVELLVMK[136.11].A "sp|Q9UNM6|PSD13_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 2 1394.7934 1.39 8415 21985 2 1394.793531 698.404 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 4.53 3942.9 - 1.93E+06 - - - 0.066 - 2.869 0.488 - 600.5 1 2 0 0.0001 12 0 0 0 2.05E+07 1.48E+07 - - - 5.4185 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.21987.21987.2 0.0555 22-Nov R.VALILQNVDLPN.- "sp|Q04446|GLGB_HUMAN,tr|E9PGM4|E9PGM4_HUMAN" 2 1307.7449 - 8417 21987 2 1307.744274 654.8797 "1,4-alpha-glucan-branching enzyme OS=Homo sapiens OX=9606 GN=GBE1 PE=1 SV=3" 3.8 3943.1 - 1.53E+06 - - - -0.4802 - 2.189 0.381 - 256.5 1 2 0 -0.0006 12 0 0 0 - - - - - 3.9162 0.9902 230117_WJC_METTL3_WT_vs_EV_F01.21988.21988.2 0.0658 12-Jun K.ELFSFFR.D "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 944.4756 1.88 8418 21988 2 944.474457 473.2451 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6.1 3943.1 - 1.15E+06 - - - -1.2134 - 1.34 0.184 - 151.3 1 2 0 -0.0011 7 0 0 0 6.70E+06 3.57E+06 - - - 1.327 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.21994.21994.2 0.195 22-Nov K.VLLVLELQGLQK.N sp|Q14697|GANAB_HUMAN 1 1351.8439 1.62 8424 21994 2 1351.841698 676.9292 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 5.97 3943.9 - 589435 - - - -1.62 - 2.324 0.41 - 390 1 2 0 -0.0022 12 0 0 0 6.65E+06 4.11E+06 - - - 4.2874 1 230117_WJC_METTL3_WT_vs_EV_F01.21995.21995.2 0.133 13/22 K.VLLVLELQGLQK[136.11].N sp|Q14697|GANAB_HUMAN 1 1359.8581 1.62 8425 21995 2 1359.858884 680.9363 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 5.97 3944 - 549617 - - - 0.5854 - 2.597 0.442 - 550.3 1 2 0 0.0008 12 0 0 0 6.65E+06 4.11E+06 - - - 4.8164 0.9944 230117_WJC_METTL3_WT_vs_EV_F01.21998.21998.2 0.0111 24-Sep R.LLDISASSTEQIL.- "sp|O43615|TIM44_HUMAN,tr|M0QXM9|M0QXM9_HUMAN" 2 1388.7399 - 8426 21998 2 1388.735928 695.3772 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.67 3944.4 - 1.02E+07 - - - -2.8429 - 1.895 0.298 - 257.4 1 2 0 -0.0039 13 0 0 0 - - - - - 2.8814 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.22001.22001.2 0.0147 20-Nov K.AIVEFLSNLAR[166.11].H sp|Q13112|CAF1B_HUMAN 1 1241.7007 1.62 8429 22001 2 1241.701458 621.8576 Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1 6.05 3944.5 - 1.96E+06 - - - 0.5766 - 1.936 0.27 - 492.8 1 2 0 0.0007 11 0 0 0 1.00E+07 6.16E+06 - - - 2.8221 0.9972 230117_WJC_METTL3_WT_vs_EV_F01.22002.22002.2 0.643 16-Sep R.DILALMEVK.M sp|Q96EK4|THA11_HUMAN 1 1030.5733 1.57 8430 22002 2 1030.572089 516.2939 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 4.37 3944.6 - 1.81E+06 - - - -1.144 - 1.979 0.194 - 254 1 2 0 -0.0012 9 0 0 0 5.53E+06 3.52E+06 - - - 2.4483 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.22008.22008.3 5.66E-05 14/52 K.QIALAVLSTELAVR[166.11].K "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1492.8852 -1 8436 22008 3 1492.882749 498.6357 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3945.4 - 768227 - - - -1.6746 - 2.422 0.381 - 328.5 1 2 0 -0.0025 14 0 0 0 0.00E+00 0.00E+00 - - - 5.1379 0.9843 230117_WJC_METTL3_WT_vs_EV_F01.22009.22009.3 0.0298 Nov-56 R.ELLFHPALFEVPSLK.L "sp|Q9UHY1|NRBP_HUMAN,tr|F8W6G1|F8W6G1_HUMAN" 2 1738.9658 2.66 8437 22009 3 1738.961292 580.6625 Nuclear receptor-binding protein OS=Homo sapiens OX=9606 GN=NRBP1 PE=1 SV=1 5.4 3945.5 - 735421 - - - -2.5889 - 1.453 0.271 - 84.7 1 2 0 -0.0045 15 0 0 0 4.14E+06 1.56E+06 - - - 2.5351 1 230117_WJC_METTL3_WT_vs_EV_F01.22010.22010.2 0.0189 17/26 K.QIALAVLSTELAVR[166.11].K "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1492.8852 -1 8438 22010 2 1492.886935 747.4499 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3945.6 - 703197 - - - 1.1294 - 3.05 0.441 - 1159.6 1 2 0 0.0017 14 0 0 0 0.00E+00 0.00E+00 - - - 5.0961 1 230117_WJC_METTL3_WT_vs_EV_F01.22012.22012.2 8.32E-07 17/28 R.VLAFLSSVAGDALTR[166.11].H sp|Q92616|GCN1_HUMAN 1 1528.8489 1.4 8440 22012 2 1528.849918 765.4317 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3945.9 - 557486 - - - 0.6901 - 3.283 0.575 - 1161.8 1 2 0 0.0011 15 0 0 0 5.55E+06 3.96E+06 - - - 6.2102 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.22017.22017.2 7.69E-05 18-Nov K.ADLTALFLPR.Q sp|Q13045|FLII_HUMAN 1 1115.6339 1.81 8444 22017 2 1115.634052 558.8242 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.88 3946.6 - 1.23E+06 - - - 0.1407 - 2.509 0.299 - 378.6 1 2 0 0.0002 10 0 0 0 2.04E+07 1.13E+07 - - - 3.817 1 230117_WJC_METTL3_WT_vs_EV_F01.22019.22019.2 6.88E-08 26-Dec K.LYSPSQIGAFVLMK.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1552.8323 4.62 8446 22019 2 1552.833825 777.4234 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3946.8 - 1.19E+07 - - - 0.9582 - 2.616 0.598 - 453.9 1 2 0 0.0015 14 0 0 0 1.16E+08 2.51E+07 - - - 5.8706 1 230117_WJC_METTL3_WT_vs_EV_F01.22020.22020.2 0.012 20-Dec K.DFAPVIVEAFK.H "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1234.6598 2.12 8447 22020 2 1234.66106 618.3372 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.37 3946.8 - 3.74E+06 - - - 1.0408 - 2.275 0.509 - 431.3 1 2 0 0.0013 11 0 0 0 2.50E+07 1.18E+07 - - - 5.0237 1 230117_WJC_METTL3_WT_vs_EV_F01.22021.22021.2 5.74E-09 15/26 K.LYSPSQIGAFVLMK[136.11].M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1560.8465 4.62 8448 22021 2 1560.847291 781.4305 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3946.9 - 3.00E+06 - - - 0.4831 - 2.87 0.631 - 697.3 1 2 0 0.0008 14 0 0 0 1.16E+08 2.51E+07 - - - 6.3471 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.22022.22022.2 0.000574 16-Sep R.NLPFDFTWK.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1166.576 2.76 8449 22022 2 1166.578465 584.2953 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3947 - 2.10E+06 - - - 2.0736 - 1.656 0.287 - 214.1 1 2 0 0.0024 9 0 0 0 2.29E+08 8.31E+07 - - - 2.6193 0.8995 230117_WJC_METTL3_WT_vs_EV_F01.22023.22023.3 0.0109 13/56 R.VLAFLSSVAGDALTR[166.11].H sp|Q92616|GCN1_HUMAN 1 1528.8489 1.23 8450 22023 3 1529.852146 510.6236 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3947.1 - 1.97E+06 - - - 656.2343 - 2.374 0.217 - 207.8 1 2 0 1.0033 15 0 0 0 3.89E+06 3.17E+06 - - - 2.9374 1 230117_WJC_METTL3_WT_vs_EV_F01.22025.22025.2 2.64E-07 18/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 -1 8452 22025 2 1591.948214 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3947.3 - 1.80E+06 - - - 2.0195 - 2.998 0.527 - 760.9 1 2 0 0.0032 15 0 0 0 0.00E+00 0.00E+00 - - - 5.6318 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.22026.22026.2 0.00109 20-Nov K.DFAPVIVEAFK[136.11].H "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1242.674 2.23 8453 22026 2 1242.673486 622.3443 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.37 3947.4 - 1.66E+06 - - - -0.3935 - 2.033 0.463 - 367.3 1 2 0 -0.0005 11 0 0 0 2.50E+07 1.12E+07 - - - 4.38 1 230117_WJC_METTL3_WT_vs_EV_F01.22027.22027.2 0.000341 15/20 K.TPVLFDIYEIK.E sp|P50995|ANX11_HUMAN 1 1336.7279 6.49 8454 22027 2 1336.72902 669.3712 Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1 4.37 3947.5 - 1.51E+06 - - - 0.8715 - 3.21 0.545 - 1320.8 1 2 0 0.0012 11 0 0 0 6.24E+06 9.62E+05 - - - 6.221 1 230117_WJC_METTL3_WT_vs_EV_F01.22028.22028.2 3.07E-06 15/32 R.AIGLSPMSFPTADLTLK.M "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1760.9383 -1 8455 22028 2 1760.940222 881.4764 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.88 3947.6 - 1.48E+06 - - - 1.1153 - 3.024 0.518 - 668.8 1 2 0 0.002 17 0 0 0 0.00E+00 0.00E+00 - - - 5.5869 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22030.22030.3 2.01E-06 13/56 R.VLAFLSSVAGDALTR.H sp|Q92616|GCN1_HUMAN 1 1518.8406 1.15 8457 22030 3 1518.841759 507.2875 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3947.9 - 1.39E+06 - - - 0.7677 - 2.255 0.457 - 198.3 1 2 0 0.0012 15 0 0 0 3.55E+06 3.08E+06 - - - 5.7566 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.22032.22032.2 0.0102 18-Sep R.EEIYEYIIFR.G "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 1373.6867 -1 8459 22032 2 1373.686853 687.8506 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.25 3948.1 - 1.25E+06 - - - 0.0983 - 2.037 0.392 - 335.4 1 2 0 0.0001 10 0 0 0 0.00E+00 0.00E+00 - - - 3.9222 1 230117_WJC_METTL3_WT_vs_EV_F01.22035.22035.2 1.72E-08 18/32 R.AIGLSPMSFPTADLTLK[136.11].M "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1768.9525 -1 8462 22035 2 1768.952571 885.4835 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.88 3948.5 - 1.09E+06 - - - 0.0639 - 3.425 0.611 - 1026.4 1 2 0 0.0001 17 0 0 0 0.00E+00 0.00E+00 - - - 6.5805 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.22039.22039.2 0.000145 18-Dec R.LLELQYFISR[166.11].D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1290.7211 -1 8465 22039 2 1290.72368 646.3678 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 6 3948.9 - 4.60E+06 - - - 1.9656 - 2.29 0.429 - 639.2 1 2 0 0.0025 10 0 0 0 0.00E+00 0.00E+00 - - - 4.5215 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22040.22040.3 0.000914 14/56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 5.19 8466 22040 3 1591.945063 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3948.9 - 2.39E+07 - - - 0.0402 - 2.599 0.417 - 204.7 1 2 0 0.0001 15 0 0 0 1.10E+08 2.12E+07 - - - 5.6814 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22041.22041.3 3.58E-05 13/52 K.LYSPSQIGAFVLMK.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1552.8323 4.99 8467 22041 3 1552.832333 518.6181 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3949 - 1.03E+07 - - - -0.0026 - 2.521 0.502 - 308.7 1 2 0 0 14 0 0 0 3.61E+07 7.23E+06 - - - 6.5941 1 230117_WJC_METTL3_WT_vs_EV_F01.22042.22042.3 7.34E-15 21/72 R.GPLLVQDVVFTDEMAHFDR.E sp|P04040|CATA_HUMAN 1 2188.0623 999 8468 22042 3 2188.063401 730.3614 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 4.22 3949 - 9.09E+06 - - - 0.5078 - 3.872 0.737 - 607.2 1 2 0 0.0011 19 0 0 0 2.01E+07 0.00E+00 - - - 10.0825 1 230117_WJC_METTL3_WT_vs_EV_F01.22043.22043.2 1.43E-08 14/28 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 -1 8469 22043 2 1601.95354 801.9839 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3949 - 7.84E+06 - - - 0.1692 - 2.846 0.652 - 457.6 1 2 0 0.0003 15 0 0 0 0.00E+00 0.00E+00 - - - 6.428 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.22044.22044.2 0.000139 16-Oct R.NLPFDFTWK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1174.5902 2.75 8470 22044 2 1174.588947 588.3024 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3949.1 - 4.78E+06 - - - -1.1059 - 1.78 0.502 - 292.5 1 2 0 -0.0013 9 0 0 0 2.29E+08 8.31E+07 - - - 4.4165 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.22047.22047.2 0.00736 18-Oct R.LLELQYFISR.D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1280.7129 -1 8473 22047 2 1280.712623 641.3637 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 6 3949.2 - 3.57E+06 - - - -0.1952 - 2.164 0.342 - 440.5 1 2 0 -0.0003 10 0 0 0 0.00E+00 0.00E+00 - - - 3.7217 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22049.22049.2 3.46E-06 22-Dec R.TLITFAGMIPYR.T "sp|Q8N1F7|NUP93_HUMAN,tr|H3BV15|H3BV15_HUMAN" 2 1381.7428 -1 8475 22049 2 1381.742824 691.8787 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 8.41 3949.4 - 2.65E+06 - - - 0.0224 - 2.491 0.364 - 532.7 1 2 0 0 12 0 0 0 0.00E+00 0.00E+00 - - - 4.1309 0.999 230117_WJC_METTL3_WT_vs_EV_F01.22050.22050.2 0.0681 14-Aug K.ISLIQIFR.A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 988.607 -1 8476 22050 2 988.607971 495.3108 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.75 3949.4 - 2.50E+06 - - - 1.0307 - 1.857 0.202 - 179.7 1 2 0 0.001 8 0 0 0 0.00E+00 0.00E+00 - - - 2.3994 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22051.22051.3 7.20E-07 Dec-52 K.LYSPSQIGAFVLMK[136.11].M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1560.8465 4.99 8477 22051 3 1560.847374 521.2895 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3949.5 - 2.35E+06 - - - 0.5362 - 2.422 0.477 - 220.9 1 2 0 0.0008 14 0 0 0 3.61E+07 7.23E+06 - - - 6.2087 1 230117_WJC_METTL3_WT_vs_EV_F01.22053.22053.2 0.000492 22-Nov K.LLPLVSDEVFIR.D sp|P11216|PYGB_HUMAN 1 1399.8075 4.45 8479 22053 2 1399.808369 700.911 "Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB PE=1 SV=5" 4.37 3949.6 - 2.23E+06 - - - 0.6194 - 2.344 0.531 - 426.8 1 2 0 0.0009 12 0 0 0 6.71E+06 1.51E+06 - - - 5.2041 1 230117_WJC_METTL3_WT_vs_EV_F01.22054.22054.2 4.38E-07 16/24 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 1.85 8480 22054 2 1509.887857 755.9512 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3949.6 - 2.17E+06 - - - -0.0139 - 3.009 0.61 - 937.3 1 2 0 0 13 0 0 0 2.96E+07 1.60E+07 - - - 6.3738 1 230117_WJC_METTL3_WT_vs_EV_F01.22062.22062.3 8.41E-05 15/56 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 5.19 8487 22062 3 1601.953712 534.9917 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3950.2 - 5.56E+06 - - - 0.2765 - 2.889 0.521 - 222.1 1 2 0 0.0004 15 0 0 0 1.04E+08 2.00E+07 - - - 7.1168 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.22064.22064.2 0.00738 18-Nov K.LLELQELVLR.L "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|A0A087WYC0|A0A087WYC0_HUMAN" 3 1224.7442 -1 8489 22064 2 1224.74401 613.3794 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 4.53 3950.3 - 2.47E+06 - - - -0.1339 - 2.384 0.286 - 417.4 1 2 0 -0.0002 10 0 0 0 0.00E+00 0.00E+00 - - - 3.5784 1 230117_WJC_METTL3_WT_vs_EV_F01.22065.22065.2 2.21E-07 24-Dec K.MFVLDEADEMLSR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 11 1564.7141 -1 8490 22065 2 1564.713024 783.3643 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 3.92 3950.4 - 2.26E+06 - - - -0.6787 - 2.429 0.572 - 446.3 1 2 0 -0.0011 13 0 0 0 0.00E+00 0.00E+00 - - - 5.5432 1 230117_WJC_METTL3_WT_vs_EV_F01.22066.22066.2 3.47E-13 17/26 R.FGDPEC[160.03]QVILPLLK.S sp|P22102|PUR2_HUMAN 1 1627.8644 -1 8491 22066 2 1627.862927 814.9395 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.37 3950.5 - 2.06E+06 - - - -0.8834 - 3.274 0.702 - 800 1 2 0 -0.0014 14 0 0 0 0.00E+00 0.00E+00 - - - 7.2018 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.22067.22067.2 1.52 18-Sep K.VLLDIFTGVR.L sp|P49916|DNLI3_HUMAN 1 1131.6652 1.96 8492 22067 2 1131.665005 566.8399 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 5.81 3950.5 - 2.03E+06 - - - -0.1679 - 1.975 0.239 - 199.4 1 2 0 -0.0002 10 0 0 0 4.66E+06 2.37E+06 - - - 2.7059 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.22068.22068.2 0.0199 13/28 R.ALVEVLGPYEPLLSR.V "sp|Q86VR2|RETR3_HUMAN,tr|K7EMF4|K7EMF4_HUMAN,tr|K7ELM8|K7ELM8_HUMAN,tr|K7EJ34|K7EJ34_HUMAN,tr|K7ENF4|K7ENF4_HUMAN,tr|K7ENZ6|K7ENZ6_HUMAN" 6 1654.9294 -1 8493 22068 2 1654.93408 828.472 Reticulophagy regulator 3 OS=Homo sapiens OX=9606 GN=RETREG3 PE=1 SV=1 4.53 3950.6 - 1.55E+06 - - - 2.8231 - 2.667 0.343 - 506.5 1 2 0 0.0047 15 0 0 0 0.00E+00 0.00E+00 - - - 3.9847 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.22069.22069.3 0.0113 13/44 R.EGGFLLLHTLLR.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1367.7925 1.35 8494 22069 3 1367.792313 456.9381 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.85 3950.7 - 1.20E+06 - - - -0.1521 - 2.287 0.383 - 210.8 1 2 0 -0.0002 12 0 0 0 3.44E+06 2.55E+06 - - - 5.103 1 230117_WJC_METTL3_WT_vs_EV_F01.22070.22070.2 4.66E-10 13/26 R.FGDPEC[160.03]QVILPLLK[136.11].S sp|P22102|PUR2_HUMAN 1 1635.8786 1.7 8495 22070 2 1635.879269 818.9466 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.37 3950.8 - 1.20E+06 - - - 0.4303 - 2.562 0.571 - 346.3 1 2 0 0.0007 14 0 0 0 5.83E+06 3.43E+06 - - - 5.619 1 230117_WJC_METTL3_WT_vs_EV_F01.22071.22071.2 1.12E-06 13/24 R.IGLFYMDNDLITR[166.11].N "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN" 2 1579.7944 -1 8496 22071 2 1579.796553 790.9045 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.21 3950.9 - 1.09E+06 - - - 1.3723 - 2.426 0.529 - 601 1 2 0 0.0022 13 0 0 0 0.00E+00 0.00E+00 - - - 5.2221 1 230117_WJC_METTL3_WT_vs_EV_F01.22072.22072.2 0.000256 15/28 R.ALVEVLGPYEPLLSR[166.11].V "sp|Q86VR2|RETR3_HUMAN,tr|K7EMF4|K7EMF4_HUMAN,tr|K7ELM8|K7ELM8_HUMAN,tr|K7EJ34|K7EJ34_HUMAN,tr|K7ENF4|K7ENF4_HUMAN,tr|K7ENZ6|K7ENZ6_HUMAN" 6 1664.9377 -1 8497 22072 2 1664.936933 833.4761 Reticulophagy regulator 3 OS=Homo sapiens OX=9606 GN=RETREG3 PE=1 SV=1 4.53 3951.1 - 938347 - - - -0.4475 - 2.595 0.476 - 618 1 2 0 -0.0007 15 0 0 0 0.00E+00 0.00E+00 - - - 4.9009 1 230117_WJC_METTL3_WT_vs_EV_F01.22075.22075.2 0.000542 13/28 K.ITGMLLEIDNSELLH.M "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YER0|H0YER0_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 23 1696.8706 - 8500 22075 2 1696.871762 849.4426 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.13 3951.4 - 825633 - - - 0.7007 - 2.63 0.455 - 410.3 1 1 0 0.0012 15 0 0 0 - - - - - 4.7786 0.9722 230117_WJC_METTL3_WT_vs_EV_F01.22078.22078.2 1.65 24-Aug K.VLAPELIPSILEK.F "sp|P50748|KNTC1_HUMAN,tr|E7ES84|E7ES84_HUMAN" 2 1420.8541 -1 8503 22078 2 1420.854048 711.4343 Kinetochore-associated protein 1 OS=Homo sapiens OX=9606 GN=KNTC1 PE=1 SV=1 4.53 3951.8 - 641043 - - - -0.0493 - 1.035 0.125 - 56.7 1 2 0 -0.0001 13 0 0 0 0.00E+00 0.00E+00 - - - 0.0525 1 230117_WJC_METTL3_WT_vs_EV_F01.22080.22080.2 2.97E-06 26-Nov K.LSPVVGAVYGPELY.A "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 7 1462.7708 - 8504 22080 2 1462.772745 732.3927 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4 3952.1 - 1.33E+06 - - - 1.342 - 2.274 0.488 - 352.9 1 1 0 0.002 14 0 0 0 - - - - - 4.7064 1 230117_WJC_METTL3_WT_vs_EV_F01.22082.22082.2 0.00028 14/20 K.ILDVEIIFNER.G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1359.7398 1.27 8506 22082 2 1359.737567 680.8772 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3952.3 - 5.85E+06 - - - -1.6547 - 2.589 0.41 - 839.5 1 2 0 -0.0022 11 0 0 0 7.93E+07 6.24E+07 - - - 4.642 1 230117_WJC_METTL3_WT_vs_EV_F01.22083.22083.2 0.000304 13/24 R.NVIVLQTVLQEVR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1519.8961 1.85 8507 22083 2 1519.89674 760.9554 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3952.3 - 4.42E+06 - - - 0.3895 - 2.618 0.489 - 600.8 1 2 0 0.0006 13 0 0 0 2.96E+07 1.60E+07 - - - 5.1226 1 230117_WJC_METTL3_WT_vs_EV_F01.22084.22084.2 5.82E-06 13/26 K.GYAFIEFASFEDAK[136.11].E "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 10 1601.7493 0.68 8508 22084 2 1601.748102 801.8819 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.14 3952.3 - 2.86E+06 - - - -0.7635 - 2.27 0.571 - 491.6 1 2 0 -0.0012 14 0 0 0 1.10E+07 1.63E+07 - - - 5.3152 1 230117_WJC_METTL3_WT_vs_EV_F01.22085.22085.3 9.91E-06 15/48 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 -1 8509 22085 3 1509.888586 504.3032 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3952.4 - 2.38E+06 - - - 0.4689 - 2.777 0.524 - 402.8 1 2 0 0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 7.1511 1 230117_WJC_METTL3_WT_vs_EV_F01.22086.22086.2 3.50E-09 16/30 L.SLGLETAGGVMTALIK.R "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1559.8593 4.31 8510 22086 2 1559.860005 780.9369 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.72 3952.4 - 2.32E+06 - - - 0.4648 - 3.05 0.606 - 746.7 1 1 0 0.0007 16 0 0 0 6.99E+06 1.62E+06 - - - 6.2583 1 230117_WJC_METTL3_WT_vs_EV_F01.22087.22087.2 8.63E-07 14/24 R.IGLFYMDNDLITR.N "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN" 2 1569.7861 -1 8511 22087 2 1569.789737 785.9003 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.21 3952.5 - 1.92E+06 - - - 2.3073 - 3.068 0.577 - 817.1 1 2 0 0.0036 13 0 0 0 0.00E+00 0.00E+00 - - - 6.1787 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.22088.22088.2 0.127 16-Sep K.ILNIFGVIK.G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1015.643 -1 8512 22088 2 1015.642935 508.8288 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3952.5 - 1.59E+06 - - - -0.067 - 1.93 0.299 - 176.1 1 2 0 -0.0001 9 0 0 0 0.00E+00 0.00E+00 - - - 3.1516 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.22091.22091.2 0.000987 20-Dec K.DTLTYFIYSVK.N sp|O75446|SAP30_HUMAN 1 1348.6915 -1 8515 22091 2 1348.689497 675.353 Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1 5.83 3952.8 - 1.19E+06 - - - -1.4622 - 2.121 0.417 - 588.3 1 2 0 -0.002 11 0 0 0 0.00E+00 0.00E+00 - - - 4.1544 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22092.22092.2 0.000699 16-Sep K.ILNIFGVIK[136.11].G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1023.6572 -1 8516 22092 2 1023.65742 512.8359 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3952.8 - 1.14E+06 - - - 0.212 - 1.972 0.416 - 182.9 1 2 0 0.0002 9 0 0 0 0.00E+00 0.00E+00 - - - 4.078 0.999 230117_WJC_METTL3_WT_vs_EV_F01.22095.22095.2 0.802 22-Nov K.IVILPDYLEIAR.D sp|P45974|UBP5_HUMAN 1 1413.8232 -1 8519 22095 2 1413.821423 707.9189 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 4.37 3953.1 - 738593 - - - -1.2229 - 2.111 0.397 - 317.8 1 2 0 -0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 3.9386 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22104.22104.3 0.00312 13/40 K.ILDVEIIFNER[166.11].G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1369.7481 -1 8527 22104 3 1369.747467 457.59 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3953.9 - 3.49E+06 - - - -0.4526 - 2.274 0.326 - 320.8 1 2 0 -0.0006 11 0 0 0 0.00E+00 0.00E+00 - - - 4.5083 1 230117_WJC_METTL3_WT_vs_EV_F01.22105.22105.2 2.87E-07 13/22 R.NMLQFNLQILPK.S "sp|O15371|EIF3D_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 3 1457.8065 -1 8528 22105 2 1457.80686 729.9105 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 8.75 3954 - 2.89E+06 - - - 0.2771 - 2.693 0.516 - 706.1 1 2 0 0.0004 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4586 1 230117_WJC_METTL3_WT_vs_EV_F01.22106.22106.2 6.72E-07 22-Nov R.NMLQFNLQILPK[136.11].S "sp|O15371|EIF3D_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 3 1465.8207 1.09 8529 22106 2 1465.822406 733.9176 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 8.75 3954.1 - 2.52E+06 - - - 1.1939 - 2.301 0.561 - 458.4 1 2 0 0.0018 12 0 0 0 6.32E+06 5.82E+06 - - - 5.3767 1 230117_WJC_METTL3_WT_vs_EV_F01.22107.22107.2 1.69E-07 14/26 R.IVEPYVTWGFPNLK[136.11].S "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1669.8959 -1 8530 22107 2 1669.896962 835.9552 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6 3954.1 - 2.02E+06 - - - 0.618 - 2.534 0.598 - 605.8 1 2 0 0.001 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7908 1 230117_WJC_METTL3_WT_vs_EV_F01.22110.22110.2 0.000236 13/24 R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 8533 22110 2 1349.790313 675.9026 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3954.3 - 1.70E+06 - - - -0.2274 - 2.703 0.412 - 446.1 1 2 0 -0.0003 13 0 0 0 0.00E+00 0.00E+00 - - - 4.636 1 230117_WJC_METTL3_WT_vs_EV_F01.22115.22115.2 3.05E-13 17/28 K.YFDTVPVAAAMC[160.03]VLK.T sp|Q15393|SF3B3_HUMAN 1 1683.8364 -1 8538 22115 2 1683.835454 842.9255 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.83 3954.8 - 1.23E+06 - - - -0.5832 - 3.202 0.673 - 725.9 1 2 0 -0.001 15 0 0 0 0.00E+00 0.00E+00 - - - 6.8727 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.22116.22116.2 0.00391 26-Dec R.LPLPYGFSAMQGWR.V sp|O15355|PPM1G_HUMAN 1 1621.8075 -1 8539 22116 2 1621.810433 811.911 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 8.75 3954.9 - 1.09E+06 - - - 1.7968 - 1.68 0.361 - 262 1 2 0 0.0029 14 0 0 0 0.00E+00 0.00E+00 - - - 3.0083 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22117.22117.3 2.30E-05 16/48 R.VNILEVASGAVLR.S sp|Q12788|TBL3_HUMAN 1 1339.7823 2.22 8540 22117 3 1339.781883 447.6014 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3955 - 946108 - - - -0.3486 - 3.297 0.504 - 490.9 1 2 0 -0.0005 13 0 0 0 7.89E+06 3.55E+06 - - - 7.3936 0.9192 230117_WJC_METTL3_WT_vs_EV_F01.22120.22120.2 1.25 24-Jun R.ILPSLEDTLSLVK.R "sp|Q9NX74|DUS2L_HUMAN,tr|E7EUN9|E7EUN9_HUMAN,tr|J3QLD5|J3QLD5_HUMAN" 3 1426.8283 -1 8543 22120 2 1426.834466 714.4214 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like OS=Homo sapiens OX=9606 GN=DUS2 PE=1 SV=1 4.37 3955.3 - 816072 - - - 4.3236 - 1.228 0.108 - 48.1 6 2 0 0.0062 13 0 0 0 0.00E+00 0.00E+00 - - - 0.0163 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22122.22122.3 3.04E-07 16/48 R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 8544 22122 3 1349.788746 450.9375 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3955.5 - 1.99E+06 - - - -1.3884 - 2.984 0.497 - 527.8 1 2 0 -0.0019 13 0 0 0 0.00E+00 0.00E+00 - - - 7.0447 1 230117_WJC_METTL3_WT_vs_EV_F01.22125.22125.2 1.70E-05 20-Sep K.SVFGGLVNYFK.S "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1229.6445 -1 8547 22125 2 1229.644995 615.8295 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 8.31 3955.7 - 1.41E+07 - - - 0.4359 - 1.985 0.533 - 215.4 1 2 0 0.0005 11 0 0 0 0.00E+00 0.00E+00 - - - 4.8323 1 230117_WJC_METTL3_WT_vs_EV_F01.22126.22126.2 5.33E-06 24-Dec K.LGAGTFQLDQWLR.A sp|P50219|MNX1_HUMAN 1 1503.7834 -1 8548 22126 2 1503.783374 752.899 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 5.84 3955.8 - 9.74E+06 - - - -0.0259 - 2.805 0.449 - 523.9 1 2 0 0 13 0 0 0 0.00E+00 0.00E+00 - - - 5.0044 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.22129.22129.2 0.00813 20-Aug K.FVSISDLLVPK.D sp|P50395|GDIB_HUMAN 1 1216.7067 12.45 8551 22129 2 1216.70757 609.3606 Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2 5.84 3955.9 - 6.52E+06 - - - 0.6945 - 1.442 0.257 - 128.6 1 2 0 0.0008 11 0 0 0 1.89E+07 1.52E+06 - - - 1.9291 0.9983 230117_WJC_METTL3_WT_vs_EV_F01.22130.22130.2 4.69E-06 16/24 K.LAGFLDLTEQEFR[166.11].L "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 1547.7859 0.91 8552 22130 2 1547.79338 774.9002 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.14 3956 - 4.57E+06 - - - 4.814 - 2.744 0.362 - 1163.8 1 2 0 0.0075 13 0 0 0 4.61E+07 5.04E+07 - - - 4.3031 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.22131.22131.2 0.0061 14-Sep R.TLFLELIR.A sp|Q96GM8|TOE1_HUMAN 1 1003.6066 -1 8553 22131 2 1003.60644 502.8106 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 5.66 3956 - 4.46E+06 - - - -0.1764 - 1.718 0.331 - 340.9 1 2 0 -0.0002 8 0 0 0 0.00E+00 0.00E+00 - - - 3.1178 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.22134.22134.2 4.90E-05 18-Oct R.LGIYTVLFER.L "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 1209.6758 -1 8556 22134 2 1209.680201 605.8452 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 6 3956.2 - 3.49E+06 - - - 3.6712 - 1.897 0.415 - 277.1 1 2 0 0.0044 10 0 0 0 0.00E+00 0.00E+00 - - - 3.892 1 230117_WJC_METTL3_WT_vs_EV_F01.22135.22135.3 1.72E-06 16/48 K.LFYADHPFIFLVR.D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1636.8766 3.54 8557 22135 3 1636.87764 546.6328 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3956.2 - 3.48E+06 - - - 0.6445 - 2.953 0.553 - 264.5 1 2 0 0.0011 13 0 0 0 1.05E+08 2.96E+07 - - - 7.641 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22136.22136.3 7.04E-05 15/48 R.IESILMSLPLTAR.W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1442.8167 1.45 8558 22136 3 1442.81645 481.9462 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3956.3 - 2.52E+06 - - - -0.1643 - 2.851 0.427 - 301.7 1 2 0 -0.0002 13 0 0 0 1.10E+07 7.60E+06 - - - 6.1411 1 230117_WJC_METTL3_WT_vs_EV_F01.22137.22137.2 0.00037 26-Dec K.LDDIFEPVLIPEPK.L "sp|Q14008|CKAP5_HUMAN,tr|H0YEK7|H0YEK7_HUMAN,tr|H0YCF6|H0YCF6_HUMAN" 3 1623.876 -1 8559 22137 2 1623.876374 812.9453 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 3.92 3956.4 - 2.44E+06 - - - 0.2451 - 2.381 0.571 - 437.1 1 2 0 0.0004 14 0 0 0 0.00E+00 0.00E+00 - - - 5.4353 0.9969 230117_WJC_METTL3_WT_vs_EV_F01.22138.22138.2 0.33 20-Sep K.ATLWYVPLSLK[136.11].N "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1297.7526 -1 8560 22138 2 1297.754502 649.8836 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 8.63 3956.4 - 2.29E+06 - - - 1.4964 - 1.577 0.146 - 194.3 1 2 0 0.0019 11 0 0 0 0.00E+00 0.00E+00 - - - 1.351 0.9948 230117_WJC_METTL3_WT_vs_EV_F01.22139.22139.2 0.444 22-Jul M.VLESVVADLLNR.F sp|Q709C8|VP13C_HUMAN 1 1326.7507 -1 8561 22139 2 1326.751485 664.3826 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.37 3956.5 - 2.14E+06 - - - 0.5796 - 1.42 0.164 - 93.3 2 2 0 0.0008 12 0 0 0 0.00E+00 0.00E+00 - - - 1.0402 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.22140.22140.2 0.0939 22-Sep R.NDGVLLLQALTR.S sp|O60763|USO1_HUMAN 1 1311.7511 -1 8562 22140 2 1311.751736 656.8828 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 5.84 3956.6 - 2.07E+06 - - - 0.523 - 1.451 0.28 - 179.7 1 2 0 0.0007 12 0 0 0 0.00E+00 0.00E+00 - - - 2.0883 0.9413 230117_WJC_METTL3_WT_vs_EV_F01.22141.22141.2 0.00151 24-Dec K.TVTNAVVTVPAYF.N "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1380.7289 - 8563 22141 2 1380.729304 691.3717 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.18 3956.7 - 2.03E+06 - - - 0.2803 - 1.615 0.363 - 270.1 1 1 0 0.0004 13 0 0 0 - - - - - 2.9522 1 230117_WJC_METTL3_WT_vs_EV_F01.22143.22143.2 2.10E-07 24-Nov K.LGAGTFQLDQWLR[166.11].A sp|P50219|MNX1_HUMAN 1 1513.7917 -1 8564 22143 2 1513.790303 757.9031 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 5.84 3956.9 - 717384 - - - -0.9116 - 2.759 0.488 - 503.3 1 2 0 -0.0014 13 0 0 0 0.00E+00 0.00E+00 - - - 5.2496 0.9318 230117_WJC_METTL3_WT_vs_EV_F01.22145.22145.2 0.923 20-Jul R.VTWEPAPGEVK.G "sp|Q99715|COCA1_HUMAN,tr|D6RGG3|D6RGG3_HUMAN" 2 1211.6186 1860.43 8566 22145 2 1211.616116 606.8166 Collagen alpha-1(XII) chain OS=Homo sapiens OX=9606 GN=COL12A1 PE=1 SV=2 4.53 3957 - 1.65E+07 - - - -2.0823 - 1.29 0.074 - 181 1 2 0 -0.0025 11 0 0 0 7.56E+08 4.06E+05 - - - 0.2756 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.22146.22146.2 0.0164 20-Sep K.LILPELGPVFK[136.11].Q "sp|Q6P3W7|SCYL2_HUMAN,tr|H0YIK6|H0YIK6_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 1232.7624 0.66 8567 22146 2 1232.762201 617.3885 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6 3957 - 8.82E+06 - - - -0.1582 - 1.63 0.401 - 268.4 1 2 0 -0.0002 11 0 0 0 3.84E+07 5.78E+07 - - - 3.3244 1 230117_WJC_METTL3_WT_vs_EV_F01.22148.22148.3 1.59E-07 16/60 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 -1 8569 22148 3 1663.9507 555.6576 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3957.1 - 3.59E+06 - - - -0.1034 - 2.891 0.556 - 261.6 1 2 0 -0.0002 16 0 0 0 0.00E+00 0.00E+00 - - - 7.4627 0.949 230117_WJC_METTL3_WT_vs_EV_F01.22149.22149.2 1.04 24-Apr K.AFTYSSTLISHK[136.11]R[166.11].L sp|A8MUV8|ZN727_HUMAN 1 1527.8164 0.001 8570 22149 2 1527.819735 764.9155 Putative zinc finger protein 727 OS=Homo sapiens OX=9606 GN=ZNF727 PE=5 SV=3 9.99 3957.1 - 3.42E+06 - - - 2.1521 - 0.974 0.099 - 42 3 2 0 0.0033 13 0 0 0 0.00E+00 8.40E+07 - - - -0.5096 1 230117_WJC_METTL3_WT_vs_EV_F01.22150.22150.2 4.37E-17 23/34 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 7.35 8571 22150 2 1911.948492 956.9806 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3957.2 - 3.26E+06 - - - 1.0026 - 4.261 0.645 - 1911.3 1 2 0 0.0019 18 0 0 0 1.07E+08 1.46E+07 - - - 7.368 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.22151.22151.2 8.72E-05 20-Nov K.GFLSGLLDNVK.Q "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1161.6394 2.81 8572 22151 2 1161.638415 581.827 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.84 3957.2 - 3.08E+06 - - - -0.8256 - 2.156 0.381 - 349.1 1 2 0 -0.001 11 0 0 0 8.57E+07 3.05E+07 - - - 3.9331 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22153.22153.3 4.27E-07 15/60 K.INEAIVAVQAIIADPK[136.11].T sp|Q9Y224|RTRAF_HUMAN 1 1671.9651 -1 8574 22153 3 1671.964392 558.329 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3957.3 - 2.94E+06 - - - -0.4067 - 2.79 0.534 - 180.9 1 2 0 -0.0007 16 0 0 0 0.00E+00 0.00E+00 - - - 7.1261 1 230117_WJC_METTL3_WT_vs_EV_F01.22155.22155.2 1.28E-08 16/30 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 -1 8576 22155 2 1663.950677 832.9827 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3957.4 - 2.40E+06 - - - -0.1172 - 3.268 0.48 - 807.2 1 2 0 -0.0002 16 0 0 0 0.00E+00 0.00E+00 - - - 5.4976 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.22156.22156.3 0.00052 Nov-48 R.IESILMSLPLTAR[166.11].W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1452.825 1.45 8577 22156 3 1452.825519 485.2823 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3957.5 - 2.19E+06 - - - 0.3868 - 2.041 0.314 - 190.8 1 2 0 0.0006 13 0 0 0 1.10E+07 7.60E+06 - - - 3.975 1 230117_WJC_METTL3_WT_vs_EV_F01.22157.22157.3 4.18E-09 13/48 K.LFYADHPFIFLVR[166.11].D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1646.8849 3.54 8578 22157 3 1646.885434 549.9689 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3957.5 - 2.02E+06 - - - 0.3516 - 2.953 0.602 - 188.3 1 2 0 0.0006 13 0 0 0 1.05E+08 2.96E+07 - - - 8.1874 1 230117_WJC_METTL3_WT_vs_EV_F01.22158.22158.2 1.41E-09 19/30 K.INEAIVAVQAIIADPK[136.11].T sp|Q9Y224|RTRAF_HUMAN 1 1671.9651 -1 8579 22158 2 1671.963533 836.9898 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3957.6 - 1.40E+06 - - - -0.9205 - 3.726 0.506 - 1219.9 1 2 0 -0.0015 16 0 0 0 0.00E+00 0.00E+00 - - - 6.0116 0.999 230117_WJC_METTL3_WT_vs_EV_F01.22160.22160.2 0.00458 20-Dec K.DVLLPWYNAYR.F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1408.7139 1.06 8581 22160 2 1408.711917 705.3642 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3957.7 - 1.31E+06 - - - -1.4332 - 2.202 0.433 - 496.7 1 2 0 -0.002 11 0 0 0 1.36E+07 1.29E+07 - - - 4.3739 1 230117_WJC_METTL3_WT_vs_EV_F01.22162.22162.2 2.81E-05 20-Dec K.DVLLPWYNAYR[166.11].F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1418.7222 1.73 8583 22162 2 1418.721175 710.3684 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3957.8 - 961146 - - - -0.7267 - 2.272 0.54 - 500.3 1 2 0 -0.001 11 0 0 0 2.63E+07 1.52E+07 - - - 5.2492 1 230117_WJC_METTL3_WT_vs_EV_F01.22164.22164.2 5.08E-05 14/24 R.AAALVLQTIWGYK.E "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A804HK15|A0A804HK15_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN,tr|A0A804HIL4|A0A804HIL4_HUMAN" 7 1432.8078 -1 8584 22164 2 1432.812581 717.4112 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 8.63 3958 - 968754 - - - 3.3117 - 2.945 0.486 - 681.9 1 2 0 0.0047 13 0 0 0 0.00E+00 0.00E+00 - - - 5.4012 1 230117_WJC_METTL3_WT_vs_EV_F01.22166.22166.2 6.94E-06 13/18 K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 57.74 8586 22166 2 1146.628246 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3958.2 - 1.66E+07 - - - -0.1997 - 2.385 0.554 - 502.6 1 2 0 -0.0002 10 0 0 0 1.55E+08 2.68E+06 - - - 5.559 1 230117_WJC_METTL3_WT_vs_EV_F01.22172.22172.2 5.73E-10 20/34 K.LGGSLADSYLDEGFLLDK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1919.9608 -1 8592 22172 2 1919.958844 960.9877 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3958.5 - 4.50E+06 - - - -1.0057 - 4.078 0.684 - 1578.5 1 2 0 -0.0019 18 0 0 0 0.00E+00 0.00E+00 - - - 7.5482 1 230117_WJC_METTL3_WT_vs_EV_F01.22174.22174.2 1.06E-05 22-Oct K.GVNSYPSLFIFR.S "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0TB22|A0A7P0TB22_HUMAN,tr|A0A7P0Z4F2|A0A7P0Z4F2_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN,tr|E7EP04|E7EP04_HUMAN,tr|A0A7P0T9B7|A0A7P0T9B7_HUMAN,tr|A0A494C1G5|A0A494C1G5_HUMAN,tr|A0A7P0TB83|A0A7P0TB83_HUMAN" 10 1398.7296 1.94 8594 22174 2 1398.729142 700.3721 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 8.75 3958.6 - 3.69E+06 - - - -0.3174 - 2.361 0.564 - 222 1 2 0 -0.0004 12 0 0 0 2.52E+07 1.30E+07 - - - 5.467 1 230117_WJC_METTL3_WT_vs_EV_F01.22181.22181.2 1.95E-08 14/26 K.VVIGMDVAASEFFR.S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1539.7756 1.94 8599 22181 2 1539.773137 770.8951 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.37 3959.3 - 1.04E+07 - - - -1.5671 - 2.838 0.634 - 738.3 1 2 0 -0.0024 14 0 0 0 7.72E+07 3.99E+07 - - - 6.3406 1 230117_WJC_METTL3_WT_vs_EV_F01.22185.22185.2 4.29E-10 17/28 K.AVLDSYEYFAVLAAK.E sp|P82664|RT10_HUMAN 1 1658.8556 1.3 8603 22185 2 1658.850711 830.4351 "28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2" 4.37 3959.7 - 2.66E+06 - - - -2.9321 - 3.332 0.682 - 824.8 1 2 0 -0.0049 15 0 0 0 1.15E+07 8.87E+06 - - - 7.0358 1 230117_WJC_METTL3_WT_vs_EV_F01.22186.22186.2 1.82E-05 19/28 K.AVLDSYEYFAVLAAK[136.11].E sp|P82664|RT10_HUMAN 1 1666.8698 1.3 8604 22186 2 1666.863682 834.4422 "28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2" 4.37 3959.8 - 2.10E+06 - - - -3.6554 - 3.506 0.639 - 1039.5 1 2 0 -0.0061 15 0 0 0 1.15E+07 8.87E+06 - - - 6.8429 0.8626 230117_WJC_METTL3_WT_vs_EV_F01.22197.22197.2 0.000526 18-Sep K.ANINVENAFF.T sp|P61006|RAB8A_HUMAN 1 1137.5455 - 8613 22197 2 1137.542434 569.78 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 4 3960.8 - 2.32E+06 - - - -2.6724 - 1.965 0.492 - 145.1 1 1 0 -0.003 10 0 0 0 - - - - - 4.5595 0.9974 230117_WJC_METTL3_WT_vs_EV_F01.22199.22199.2 0.00181 20-Sep R.FILLAC[160.03]DGLFK.V "sp|Q9H0C8|ILKAP_HUMAN,tr|F8SNU7|F8SNU7_HUMAN,tr|H7C2I8|H7C2I8_HUMAN" 3 1295.6948 11.6 8615 22199 2 1295.691724 648.8547 Integrin-linked kinase-associated serine\threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1 5.83 3961 - 1.12E+06 - - - -2.3594 - 1.864 0.383 - 232.3 1 2 0 -0.0031 11 0 0 0 5.47E+06 4.72E+05 - - - 3.5535 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.22206.22206.2 0.00275 20-Oct K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 999 8620 22206 2 1106.545759 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3961.8 - 2.46E+06 - - - -0.5811 - 2.217 0.437 - 241.5 1 2 0 -0.0006 11 0 0 0 3.04E+07 0.00E+00 - - - 4.4223 1 230117_WJC_METTL3_WT_vs_EV_F01.22208.22208.3 2.28E-06 Dec-52 K.LLPVLVHTFWIDTK.N sp|Q13505|MTX1_HUMAN 1 1680.9603 1.1 8622 22208 3 1680.962237 561.3274 Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1 PE=1 SV=3 6.74 3962 - 1.83E+06 - - - 1.144 - 2.402 0.536 - 166.5 1 2 0 0.0019 14 0 0 0 6.13E+06 5.57E+06 - - - 6.8441 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.22211.22211.2 0.000838 16-Sep R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 81.18 8625 22211 2 1006.568207 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3962.3 - 1.46E+06 - - - -1.68 - 1.836 0.475 - 206 1 2 0 -0.0017 9 0 0 0 9.44E+06 1.16E+05 - - - 4.3066 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22213.22213.3 0.0315 19/52 K.LNLQFLTLHDYLLR[166.11].N "sp|O60306|AQR_HUMAN,tr|H0YH15|H0YH15_HUMAN" 2 1767.9911 1.21 8627 22213 3 1767.990024 590.3376 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 6.74 3962.5 - 1.13E+06 - - - -0.6148 - 3.643 0.396 - 667 1 2 0 -0.0011 14 0 0 0 5.58E+06 4.61E+06 - - - 6.3904 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22217.22217.3 0.000412 16/52 K.LLPVLVHTFWIDTK[136.11].N sp|Q13505|MTX1_HUMAN 1 1688.9745 1.1 8631 22217 3 1688.976162 563.9988 Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1 PE=1 SV=3 6.74 3963 - 863981 - - - 0.9757 - 2.258 0.411 - 315.8 1 2 0 0.0016 14 0 0 0 6.13E+06 5.57E+06 - - - 5.2863 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.22221.22221.2 0.000108 22-Sep R.LTLAELNQILYR[166.11].C sp|P35573|GDE_HUMAN 1 1455.8325 1.36 8635 22221 2 1455.833417 728.9235 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 6 3963.6 - 689244 - - - 0.6402 - 2.117 0.315 - 213.9 1 2 0 0.0009 12 0 0 0 1.35E+07 9.90E+06 - - - 3.3407 1 230117_WJC_METTL3_WT_vs_EV_F01.22231.22231.2 7.03E-08 15/28 R.LGLEFFDQPAVPLAR[166.11].A "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1681.9067 1.22 8644 22231 2 1681.903532 841.9606 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 4.37 3964.4 - 2.09E+06 - - - -1.8907 - 3.041 0.58 - 597.9 1 2 0 -0.0032 15 0 0 0 3.59E+07 2.94E+07 - - - 6.0582 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.22234.22234.2 0.152 14-Oct R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 8.29 8647 22234 2 1000.559396 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3964.7 - 1.46E+06 - - - 0.063 - 2.139 0.262 - 345.8 1 2 0 0.0001 8 0 0 0 9.37E+06 1.13E+06 - - - 3.2693 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.22239.22239.3 0.000751 14/56 R.LGLEFFDQPAVPLAR.A "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1671.8984 1.19 8650 22239 3 1671.89784 558.3068 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 4.37 3965.1 - 1.67E+06 - - - -0.3601 - 2.274 0.429 - 118.7 1 2 0 -0.0006 15 0 0 0 1.32E+07 1.10E+07 - - - 5.4665 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22240.22240.3 0.000954 13/44 R.FFALPYVDHFLR[166.11].L sp|Q9HD33|RM47_HUMAN 1 1533.8008 0.94 8651 22240 3 1533.79968 512.2742 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 6.74 3965.2 - 2.56E+06 - - - -0.7243 - 2.291 0.463 - 152 1 2 0 -0.0011 12 0 0 0 9.01E+06 9.63E+06 - - - 5.9995 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.22242.22242.3 0.00112 16/56 R.LGLEFFDQPAVPLAR[166.11].A "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1681.9067 1.19 8653 22242 3 1681.903318 561.6428 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 4.37 3965.3 - 2.33E+06 - - - -2.0179 - 3.205 0.435 - 335.3 1 2 0 -0.0034 15 0 0 0 1.32E+07 1.10E+07 - - - 6.428 1 230117_WJC_METTL3_WT_vs_EV_F01.22243.22243.2 0.000503 24-Dec R.ALTLGALTLPLAR[166.11].L sp|Q9BSJ8|ESYT1_HUMAN 1 1318.8212 1.29 8654 22243 2 1318.820454 660.4179 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 9.79 3965.4 - 2.23E+06 - - - -0.5596 - 2.249 0.481 - 558.8 1 2 0 -0.0007 13 0 0 0 1.87E+07 1.45E+07 - - - 4.6736 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.22244.22244.3 3.40E-06 16/44 R.FFALPYVDHFLR.L sp|Q9HD33|RM47_HUMAN 1 1523.7925 0.96 8655 22244 3 1523.790945 508.9381 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 6.74 3965.5 - 1.78E+06 - - - -1.0343 - 2.73 0.394 - 262.8 1 2 0 -0.0016 12 0 0 0 9.01E+06 9.38E+06 - - - 5.716 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.22248.22248.2 0.169 20-Aug K.LVPDLLAIVQR[166.11].K "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1245.7684 1.2 8659 22248 2 1245.768274 623.8915 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.84 3965.9 - 1.11E+06 - - - -0.1236 - 1.581 0.236 - 198.6 1 2 0 -0.0002 11 0 0 0 1.09E+07 9.09E+06 - - - 2.0232 1 230117_WJC_METTL3_WT_vs_EV_F01.22251.22251.2 0.00409 22-Dec R.LELLAAYEEVIR[166.11].E "sp|Q16643|DREB_HUMAN,tr|D6RFI1|D6RFI1_HUMAN,tr|D6R9W4|D6R9W4_HUMAN" 3 1427.79 -1 8662 22251 2 1427.789429 714.9023 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.25 3966.3 - 1.03E+06 - - - -0.3656 - 2.803 0.384 - 556.1 1 2 0 -0.0005 12 0 0 0 0.00E+00 0.00E+00 - - - 4.589 1 230117_WJC_METTL3_WT_vs_EV_F01.22258.22258.2 4.16E-06 17/26 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.24 8667 22258 2 1676.898781 839.4565 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3967.2 - 2.74E+07 - - - 0.1664 - 3.193 0.546 - 1068.2 1 2 0 0.0003 14 0 0 0 1.10E+08 8.90E+07 - - - 5.987 1 230117_WJC_METTL3_WT_vs_EV_F01.22260.22260.2 0.000207 13/26 M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 1.24 8669 22260 2 1686.906118 844.4607 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3967.3 - 2.16E+07 - - - -0.3877 - 2.959 0.545 - 513.7 1 2 0 -0.0007 14 0 0 0 1.10E+08 8.90E+07 - - - 5.7885 1 230117_WJC_METTL3_WT_vs_EV_F01.22262.22262.3 8.54E-08 14/52 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.43 8671 22262 3 1676.89868 559.9734 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3967.3 - 1.28E+07 - - - 0.1061 - 2.833 0.57 - 267.8 1 2 0 0.0002 14 0 0 0 4.14E+07 2.90E+07 - - - 7.6623 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22264.22264.3 6.75E-07 Dec-52 M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 1.43 8673 22264 3 1686.90599 563.3095 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3967.4 - 9.57E+06 - - - -0.4636 - 2.526 0.498 - 201.4 1 2 0 -0.0008 14 0 0 0 4.14E+07 2.90E+07 - - - 6.5546 1 230117_WJC_METTL3_WT_vs_EV_F01.22265.22265.2 4.31E-09 14/22 K.LIC[160.03]C[160.03]DILDVLDK.H "sp|P62258|1433E_HUMAN,tr|K7EIT4|K7EIT4_HUMAN" 2 1475.7364 1.56 8674 22265 2 1475.735559 738.8755 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 3.93 3967.5 - 8.80E+06 - - - -0.5618 - 2.684 0.63 - 686.6 1 2 0 -0.0008 12 0 0 0 2.92E+07 1.87E+07 - - - 6.2917 0.9206 230117_WJC_METTL3_WT_vs_EV_F01.22267.22267.2 0.678 20-Apr K.DLTNVQNLQK[136.11]K[136.11].H "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1315.7431 0.05 8676 22267 2 1315.741678 658.8788 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.59 3967.5 - 6.14E+06 - - - -1.0534 - 0.851 0.172 - 21.8 2 2 0 -0.0014 11 0 0 0 1.13E+06 2.15E+07 - - - -0.26 1 230117_WJC_METTL3_WT_vs_EV_F01.22269.22269.2 0.00109 13/22 R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 999 8678 22269 2 1328.716771 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3967.6 - 4.94E+06 - - - -1.4871 - 2.546 0.467 - 475.2 1 2 0 -0.002 12 0 0 0 2.94E+07 0.00E+00 - - - 4.9485 0.8588 230117_WJC_METTL3_WT_vs_EV_F01.22271.22271.2 1.64 20-Jun R.SPAMSTLLDIK.S sp|O94812|BAIP3_HUMAN 1 1174.6268 3.18 8680 22271 2 1174.621728 588.3207 BAI1-associated protein 3 OS=Homo sapiens OX=9606 GN=BAIAP3 PE=1 SV=2 5.55 3967.7 - 3.69E+06 - - - -4.2848 - 1.369 0.142 - 90.8 4 2 0 -0.005 11 0 0 0 2.07E+07 6.53E+06 - - - 0.669 1 230117_WJC_METTL3_WT_vs_EV_F01.22272.22272.2 6.50E-07 14/26 K.MQLMELAILNGTYR.D "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1651.8426 -1 8681 22272 2 1651.84116 826.9286 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 5.75 3967.8 - 3.65E+06 - - - -0.8621 - 2.963 0.608 - 560.2 1 2 0 -0.0014 14 0 0 0 0.00E+00 0.00E+00 - - - 6.257 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.22273.22273.3 9.84E-05 13/52 K.MQLMELAILNGTYR.D "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1651.8426 1.85 8682 22273 3 1651.841981 551.6215 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 5.75 3967.8 - 3.62E+06 - - - -0.365 - 2.115 0.425 - 198.8 1 2 0 -0.0006 14 0 0 0 1.17E+07 6.32E+06 - - - 5.2688 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.22274.22274.2 0.000458 26-Oct K.VPGLPTPIENMILR[166.11].Y "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1558.8781 1.29 8683 22274 2 1558.877233 780.4463 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3967.9 - 3.43E+06 - - - -0.5273 - 1.892 0.282 - 165.6 1 2 0 -0.0008 14 0 0 0 1.77E+07 1.37E+07 - - - 2.7237 0.9875 230117_WJC_METTL3_WT_vs_EV_F01.22276.22276.2 0.322 12-Jul K.DVLDSVL.- sp|P81605|DCD_HUMAN 1 759.4014 - 8685 22276 2 759.400443 380.708 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.56 3968.1 - 3.19E+06 - - - -1.3063 - 1.227 0.202 - 168.4 1 2 0 -0.001 7 0 0 0 - - - - - 1.1809 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22278.22278.2 0.00938 16-Oct R.FLILPDMLK.N sp|P62318|SMD3_HUMAN 1 1088.6304 1.34 8686 22278 2 1088.630662 545.3225 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.84 3968.3 - 2.41E+07 - - - 0.2508 - 1.842 0.408 - 364.9 1 2 0 0.0003 9 0 0 0 7.64E+07 5.69E+07 - - - 3.8216 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.22279.22279.2 0.036 16-Aug R.FLILPDMLK[136.11].N sp|P62318|SMD3_HUMAN 1 1096.6446 1.34 8687 22279 2 1096.644741 549.3296 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.84 3968.3 - 2.13E+07 - - - 0.1386 - 1.618 0.324 - 193.7 1 2 0 0.0002 9 0 0 0 7.64E+07 5.69E+07 - - - 2.8261 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.22282.22282.2 0.32 16-Sep K.AGLVELLLR.E "sp|Q13425|SNTB2_HUMAN,tr|A0A140TA73|A0A140TA73_HUMAN" 2 982.6175 -1 8690 22282 2 982.616614 492.316 Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1 6.05 3968.4 - 5.08E+06 - - - -0.918 - 2.211 0.288 - 292.7 1 2 0 -0.0009 9 0 0 0 0.00E+00 0.00E+00 - - - 3.4634 1 230117_WJC_METTL3_WT_vs_EV_F01.22285.22285.2 2.58E-05 14/22 R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 -1 8693 22285 2 1301.707547 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3968.6 - 2.97E+06 - - - -0.2312 - 2.855 0.492 - 495.8 1 2 0 -0.0003 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4351 1 230117_WJC_METTL3_WT_vs_EV_F01.22286.22286.3 2.48E-06 21/64 K.LPIFFFGTHETAFLGPK[136.11].D sp|O75475|PSIP1_HUMAN 1 1929.028 1.1 8694 22286 3 1929.020568 644.0166 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 6.75 3968.7 - 2.75E+06 - - - -3.8563 - 3.573 0.588 - 515.7 1 2 0 -0.0074 17 0 0 0 1.05E+07 9.54E+06 - - - 8.3106 0.999 230117_WJC_METTL3_WT_vs_EV_F01.22288.22288.2 0.000375 13/20 K.LSSDVLTLLIK[136.11].Q "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN" 3 1208.7471 0.2 8696 22288 2 1208.746121 605.3808 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 5.84 3968.8 - 1.95E+06 - - - -0.843 - 2.565 0.263 - 281.2 1 2 0 -0.001 11 0 0 0 5.50E+06 2.73E+07 - - - 3.5314 1 230117_WJC_METTL3_WT_vs_EV_F01.22289.22289.2 4.14E-05 16/24 R.IASGLGLAWIVGR[166.11].V "sp|O14880|MGST3_HUMAN,tr|Q5VV87|Q5VV87_HUMAN,tr|Q5VV89|Q5VV89_HUMAN" 3 1321.7746 -1 8697 22289 2 1321.771994 661.8946 Microsomal glutathione S-transferase 3 OS=Homo sapiens OX=9606 GN=MGST3 PE=1 SV=1 9.75 3968.9 - 1.45E+06 - - - -1.9534 - 3.158 0.451 - 1309.9 1 2 0 -0.0026 13 0 0 0 0.00E+00 0.00E+00 - - - 5.3226 1 230117_WJC_METTL3_WT_vs_EV_F01.22290.22290.4 7.44E-11 26/162 R.PHNVQPNWITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 3130.6312 -1 8698 22290 4 3130.637766 783.6651 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.14 3969 - 1.35E+06 - - - 2.0922 - 3.981 0.591 - 239.7 1 1 0 0.0066 28 0 0 0 0.00E+00 0.00E+00 - - - 4.7972 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22292.22292.3 0.0149 16/48 R.C[160.03]LFTLLGHLDYIR.T "sp|P53621|COPA_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ITX2|A0A3B3ITX2_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 6 1619.8494 3.85 8700 22292 3 1619.850082 540.9571 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 6.73 3969.2 - 1.08E+06 - - - 0.4309 - 2.655 0.386 - 399.3 1 2 0 0.0007 13 0 0 0 4.50E+06 1.17E+06 - - - 5.4908 0.9946 230117_WJC_METTL3_WT_vs_EV_F01.22295.22295.2 0.498 20-Oct K.VNLLSVLEAAK[136.11].M sp|Q9BRX8|PXL2A_HUMAN 1 1163.7005 -1 8703 22295 2 1163.698582 582.8575 Peroxiredoxin-like 2A OS=Homo sapiens OX=9606 GN=PRXL2A PE=1 SV=3 5.97 3969.5 - 809238 - - - -1.6688 - 1.672 0.229 - 280.4 1 2 0 -0.0019 11 0 0 0 0.00E+00 0.00E+00 - - - 2.1223 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.22304.22304.2 0.00532 24-Oct K.IPLKPPPLELLNV.- sp|O15504|NUP42_HUMAN 1 1441.8908 1.89 8711 22304 2 1441.890745 721.9527 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 3970.4 - 2.11E+06 - - - -0.0645 - 1.988 0.385 - 290.9 1 2 0 -0.0001 13 0 0 0 8.03E+06 4.24E+06 - - - 3.6481 1 230117_WJC_METTL3_WT_vs_EV_F01.22305.22305.2 1.25E-06 14-Nov R.C[160.03]FLSWLVK.L sp|Q92900|RENT1_HUMAN 1 1051.5525 0.36 8712 22305 2 1051.552573 526.7835 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.22 3970.5 - 2.10E+06 - - - 0.0941 - 2.132 0.57 - 501.6 1 2 0 0.0001 8 0 0 0 5.47E+06 1.50E+07 - - - 5.5342 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.22306.22306.2 0.000926 20-Sep K.LVLADLLEPVK[136.11].T sp|Q9BVJ6|UT14A_HUMAN 1 1216.7522 1.69 8713 22306 2 1216.7511 609.3834 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3970.5 - 1.98E+06 - - - -0.9254 - 1.821 0.365 - 187.8 1 2 0 -0.0011 11 0 0 0 2.73E+07 1.61E+07 - - - 3.358 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22308.22308.3 3.88E-06 17/68 K.LLGTIYTAAEEIEAVGGK.A sp|Q6YN16|HSDL2_HUMAN 1 1833.9724 -1 8715 22308 3 1833.971438 612.3314 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3970.7 - 1.80E+06 - - - -0.5218 - 3.17 0.495 - 411.8 1 2 0 -0.001 18 0 0 0 0.00E+00 0.00E+00 - - - 6.9314 1 230117_WJC_METTL3_WT_vs_EV_F01.22312.22312.2 7.66E-07 14/22 K.QFEELTLGEFLK.L "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1452.75 -1 8719 22312 2 1452.750367 727.3823 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.25 3971.1 - 1.32E+06 - - - 0.2203 - 2.763 0.511 - 884.3 1 2 0 0.0003 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4892 1 230117_WJC_METTL3_WT_vs_EV_F01.22314.22314.2 1.58E-09 19/34 K.LLGTIYTAAEEIEAVGGK.A sp|Q6YN16|HSDL2_HUMAN 1 1833.9724 -1 8721 22314 2 1833.972015 917.9935 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3971.4 - 1.23E+06 - - - -0.2072 - 3.898 0.636 - 1300.9 1 2 0 -0.0004 18 0 0 0 0.00E+00 0.00E+00 - - - 7.0831 1 230117_WJC_METTL3_WT_vs_EV_F01.22318.22318.2 7.86E-05 28-Dec K.VNALLPTETFIPVIR[166.11].G "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1691.985 -1 8725 22318 2 1691.990282 846.9998 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.97 3971.9 - 879242 - - - 3.1436 - 2.427 0.537 - 323.3 1 2 0 0.0053 15 0 0 0 0.00E+00 0.00E+00 - - - 5.1855 0.9982 230117_WJC_METTL3_WT_vs_EV_F01.22320.22320.2 0.00374 20-Jul K.TFSFAIPLIEK[136.11].L sp|Q9NR30|DDX21_HUMAN 1 1272.7209 0.93 8726 22320 2 1272.720117 637.3677 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.66 3972.1 - 872204 - - - -0.6349 - 1.29 0.388 - 111.9 1 2 0 -0.0008 11 0 0 0 9.53E+07 1.03E+08 - - - 2.5954 1 230117_WJC_METTL3_WT_vs_EV_F01.22321.22321.2 1.11E-06 18-Oct K.GGFDWNLVFK.W sp|Q10471|GALT2_HUMAN 1 1181.5869 -1 8727 22321 2 1181.585846 591.8007 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.84 3972.2 - 3.60E+06 - - - -0.9301 - 1.956 0.564 - 211.9 1 2 0 -0.0011 10 0 0 0 0.00E+00 0.00E+00 - - - 5.079 1 230117_WJC_METTL3_WT_vs_EV_F01.22323.22323.2 0.000343 15/22 K.GDLDLELVLLC[160.03]K[136.11].E "sp|Q12906|ILF3_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 1394.7571 -1 8729 22323 2 1394.758698 698.3858 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.03 3972.3 - 4.07E+06 - - - 1.1794 - 3.019 0.549 - 1003.5 1 2 0 0.0016 12 0 0 0 0.00E+00 0.00E+00 - - - 6.0026 1 230117_WJC_METTL3_WT_vs_EV_F01.22324.22324.2 7.06E-07 14/22 K.GDLDLELVLLC[160.03]K.E "sp|Q12906|ILF3_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 1386.7429 -1 8730 22324 2 1386.744069 694.3787 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.03 3972.4 - 3.65E+06 - - - 0.8769 - 2.902 0.593 - 821.9 1 2 0 0.0012 12 0 0 0 0.00E+00 0.00E+00 - - - 6.2238 0.9733 230117_WJC_METTL3_WT_vs_EV_F01.22327.22327.2 5.02 12-Jul K.NIFLLFK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 893.5375 -1 8733 22327 2 893.538095 447.776 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.75 3972.6 - 1.89E+06 - - - 0.6939 - 1.232 0.023 - 201.2 1 2 0 0.0006 7 0 0 0 0.00E+00 0.00E+00 - - - -0.1282 0.9365 230117_WJC_METTL3_WT_vs_EV_F01.22328.22328.2 0.00393 16-Aug K.NVALLSQLY.H sp|Q15717|ELAV1_HUMAN 1 1019.5651 - 8734 22328 2 1019.565933 510.7898 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 5.52 3972.8 - 1.27E+06 - - - 0.7709 - 1.434 0.346 - 146.7 1 1 0 0.0008 9 0 0 0 - - - - - 2.6392 1 230117_WJC_METTL3_WT_vs_EV_F01.22329.22329.2 3.87E-08 13/26 R.VLDVNLMGTFNVIR[166.11].L "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 1599.8682 -1 8735 22329 2 1599.869372 800.9414 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 5.81 3972.9 - 1.24E+06 - - - 0.7213 - 2.562 0.539 - 592.6 1 2 0 0.0012 14 0 0 0 0.00E+00 0.00E+00 - - - 5.3826 0.988 230117_WJC_METTL3_WT_vs_EV_F01.22331.22331.2 0.982 18-Sep K.DLALYENLFK[136.11].K "sp|Q9BVQ7|SPA5L_HUMAN,tr|H0YCA5|H0YCA5_HUMAN" 2 1232.6532 -1 8737 22331 2 1232.65633 617.3339 Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2 4.37 3973.1 - 1.14E+06 - - - 2.5068 - 1.31 0.105 - 183.5 1 2 0 0.0031 10 0 0 0 0.00E+00 0.00E+00 - - - 0.5693 0.9572 230117_WJC_METTL3_WT_vs_EV_F01.22332.22332.2 8.93 12-May K.NIFLLFK[136.11].K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 901.5517 -1 8738 22332 2 901.552235 451.7831 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.75 3973.2 - 1.03E+06 - - - 0.6212 - 1.182 0.001 - 74.9 1 2 0 0.0006 7 0 0 0 0.00E+00 0.00E+00 - - - -0.422 0.9759 230117_WJC_METTL3_WT_vs_EV_F01.22335.22335.2 0.149 22-Jun K.QFEELTLGEFLK[136.11].L "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1460.7642 -1 8741 22335 2 1460.770986 731.3894 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.25 3973.6 - 942428 - - - 4.6133 - 1.384 0.192 - 54.4 4 2 0 0.0067 12 0 0 0 0.00E+00 0.00E+00 - - - 1.0431 1 230117_WJC_METTL3_WT_vs_EV_F01.22336.22336.3 3.38E-07 14/56 K.NLAEALLTYETLDAK.E sp|Q96TA2|YMEL1_HUMAN 1 1663.8669 1.75 8742 22336 3 1663.869854 555.6296 ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX=9606 GN=YME1L1 PE=1 SV=2 4.14 3973.7 - 858378 - - - 1.7946 - 2.896 0.481 - 333.6 1 2 0 0.003 15 0 0 0 2.67E+06 1.53E+06 - - - 6.6765 1 230117_WJC_METTL3_WT_vs_EV_F01.22337.22337.2 0.000101 15/26 K.IVQVALNGLENILR.L "sp|O60684|IMA7_HUMAN,sp|O15131|IMA6_HUMAN,sp|P52294|IMA5_HUMAN" 3 1550.9144 -1 8743 22337 2 1550.916182 776.4645 Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1 6 3973.9 - 787731 - - - 1.1316 - 3.129 0.505 - 1024.1 1 2 0 0.0018 14 0 0 0 0.00E+00 0.00E+00 - - - 5.6329 0.9887 230117_WJC_METTL3_WT_vs_EV_F01.22338.22338.2 0.309 22-Oct K.IIIPPFLAYGEK.G sp|Q96AY3|FKB10_HUMAN 1 1359.7802 -1 8744 22338 2 1359.785314 680.8974 Peptidyl-prolyl cis-trans isomerase FKBP10 OS=Homo sapiens OX=9606 GN=FKBP10 PE=1 SV=1 6 3974 - 721814 - - - 3.7425 - 1.325 0.189 - 313.8 1 2 0 0.0051 12 0 0 0 0.00E+00 0.00E+00 - - - 1.1758 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22342.22342.2 0.000519 22-Nov K.LTLIDPETLLPR.L "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1379.8024 1.49 8747 22342 2 1379.802861 690.9085 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 4.37 3974.4 - 628071 - - - 0.3218 - 2.265 0.405 - 381.6 1 2 0 0.0004 12 0 0 0 4.92E+06 3.31E+06 - - - 4.1834 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22343.22343.3 0.496 16/44 K.C[160.03]LVFSLIGLHFK[136.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1440.8043 0.84 8748 22343 3 1440.804505 481.2754 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3974.5 - 5.06E+06 - - - 0.1576 - 2.539 0.395 - 364.6 1 2 0 0.0002 12 0 0 0 1.44E+07 1.72E+07 - - - 5.5265 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22344.22344.3 7.46E-06 17/44 K.C[160.03]LVFSLIGLHFK.L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1432.7901 0.84 8749 22344 3 1432.789517 478.604 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3974.5 - 3.58E+06 - - - -0.3915 - 2.677 0.464 - 524.9 1 2 0 -0.0006 12 0 0 0 1.44E+07 1.72E+07 - - - 6.4424 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.22345.22345.2 0.00384 16-Oct R.VNILFDFVK.K sp|P55010|IF5_HUMAN 1 1093.6172 -1 8750 22345 2 1093.618494 547.8159 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.81 3974.6 - 3.56E+06 - - - 1.1997 - 2.163 0.404 - 463.6 1 2 0 0.0013 9 0 0 0 0.00E+00 0.00E+00 - - - 4.2565 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.22346.22346.2 0.0708 16-Sep R.VNILFDFVK[136.11].K sp|P55010|IF5_HUMAN 1 1101.6314 -1 8751 22346 2 1101.629043 551.823 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.81 3974.6 - 3.15E+06 - - - -2.1232 - 1.882 0.287 - 331.7 1 2 0 -0.0023 9 0 0 0 0.00E+00 0.00E+00 - - - 2.9894 0.9945 230117_WJC_METTL3_WT_vs_EV_F01.22347.22347.2 0.213 14-Aug K.GSLLDFLK.E "sp|P07947|YES_HUMAN,sp|P09769|FGR_HUMAN,sp|P07948|LYN_HUMAN,sp|P08631|HCK_HUMAN,sp|P06241|FYN_HUMAN,sp|P12931|SRC_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|J3QRU1|J3QRU1_HUMAN" 9 891.5066 -1 8752 22347 2 891.506136 446.7606 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 3974.7 - 3.13E+06 - - - -0.4857 - 1.476 0.165 - 216.8 1 2 0 -0.0004 8 0 0 0 0.00E+00 0.00E+00 - - - 1.4338 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22348.22348.2 0.00942 18-Nov K.STLLLLLTGK[136.11].L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1065.6889 0.99 8753 22348 2 1065.689083 533.8517 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3974.7 - 2.76E+06 - - - 0.1745 - 2.243 0.433 - 460.3 1 2 0 0.0002 10 0 0 0 1.14E+07 1.16E+07 - - - 4.4939 1 230117_WJC_METTL3_WT_vs_EV_F01.22352.22352.2 0.000424 24-Dec R.LLSLISIALPENK.V "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1409.8494 3.06 8757 22352 2 1409.850107 705.932 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 6 3975 - 2.13E+06 - - - 0.5249 - 2.691 0.526 - 438.9 1 2 0 0.0007 13 0 0 0 7.75E+06 2.53E+06 - - - 5.4664 1 230117_WJC_METTL3_WT_vs_EV_F01.22355.22355.2 4.00E-09 13/22 R.LGDPLEAFPVFK.K "sp|Q86UY6|NAA40_HUMAN,tr|F5H2C9|F5H2C9_HUMAN" 2 1331.7125 1.53 8760 22355 2 1331.716546 666.8635 N-alpha-acetyltransferase 40 OS=Homo sapiens OX=9606 GN=NAA40 PE=1 SV=1 4.37 3975.3 - 960548 - - - 3.0089 - 2.705 0.556 - 616.4 1 2 0 0.004 12 0 0 0 9.88E+06 6.48E+06 - - - 5.7646 1 230117_WJC_METTL3_WT_vs_EV_F01.22360.22360.2 4.43E-07 14/28 R.AVPVWDVLASGYVSR.A "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 8 1617.8515 -1 8765 22360 2 1617.860362 809.933 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.88 3975.9 - 365384 - - - 5.4826 - 2.14 0.557 - 411 1 2 0 0.0089 15 0 0 0 0.00E+00 0.00E+00 - - - 5.0227 1 230117_WJC_METTL3_WT_vs_EV_F01.22364.22364.2 5.63E-05 18-Oct K.STLLLLLTGK.L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1057.6747 -1 8768 22364 2 1057.67543 529.8446 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3976.4 - 5.83E+06 - - - 0.693 - 2.198 0.58 - 331.4 1 2 0 0.0007 10 0 0 0 0.00E+00 0.00E+00 - - - 5.5229 1 230117_WJC_METTL3_WT_vs_EV_F01.22367.22367.2 5.88E-06 18-Oct R.DFVVGALILR.S sp|Q9NUD5|ZCHC3_HUMAN 1 1101.6546 -1 8771 22367 2 1101.652441 551.8346 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 5.84 3976.5 - 2.18E+06 - - - -1.987 - 1.85 0.552 - 434.7 1 2 0 -0.0022 10 0 0 0 0.00E+00 0.00E+00 - - - 4.8346 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22368.22368.2 1.78E-05 18-Sep R.DFVVGALILR[166.11].S sp|Q9NUD5|ZCHC3_HUMAN 1 1111.6629 -1 8772 22368 2 1111.663551 556.8387 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 5.84 3976.6 - 2.14E+06 - - - 0.5856 - 1.736 0.463 - 325.3 1 2 0 0.0006 10 0 0 0 0.00E+00 0.00E+00 - - - 4.0002 0.9951 230117_WJC_METTL3_WT_vs_EV_F01.22369.22369.2 0.0423 14-Jul R.GFGFILFK.D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 927.5218 0.9 8773 22369 2 927.522081 464.7682 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3976.7 - 1.44E+06 - - - 0.276 - 1.268 0.194 - 147.5 1 2 0 0.0003 8 0 0 0 4.49E+07 4.97E+07 - - - 1.1899 1 230117_WJC_METTL3_WT_vs_EV_F01.22371.22371.2 0.000244 20-Oct R.LWGLTEMFPER.V sp|Q9NS69|TOM22_HUMAN 1 1377.6751 1.28 8775 22371 2 1377.676158 689.8448 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 4.53 3977 - 1.18E+06 - - - 0.7622 - 2.119 0.498 - 377.1 1 2 0 0.001 11 0 0 0 9.11E+06 7.11E+06 - - - 4.7504 1 230117_WJC_METTL3_WT_vs_EV_F01.22374.22374.2 0.000702 14/26 K.IFFIDPNERPVTLY.H "sp|O95619|YETS4_HUMAN,tr|F8W1B9|F8W1B9_HUMAN,tr|F8VTR4|F8VTR4_HUMAN" 3 1722.8981 -1 8778 22374 2 1722.899268 862.4563 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 4.37 3977.3 - 984765 - - - 0.6733 - 2.609 0.488 - 407.2 1 1 0 0.0012 14 0 0 0 0.00E+00 0.00E+00 - - - 5.0515 1 230117_WJC_METTL3_WT_vs_EV_F01.22378.22378.3 2.83E-10 17/60 R.LLLLLGAAAAAASQTR.G sp|Q12849|GRSF1_HUMAN 1 1538.9144 -1 8782 22378 3 1538.917263 513.9788 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 9.75 3977.7 - 488982 - - - 1.8429 - 3.106 0.63 - 350 1 2 0 0.0028 16 0 0 0 0.00E+00 0.00E+00 - - - 8.4711 1 230117_WJC_METTL3_WT_vs_EV_F01.22383.22383.2 4.30E-08 18/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 5.35 8786 22383 2 1591.945537 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3978.3 - 3.84E+06 - - - 0.338 - 3.034 0.61 - 692.7 1 2 0 0.0005 15 0 0 0 3.26E+07 6.10E+06 - - - 6.275 1 230117_WJC_METTL3_WT_vs_EV_F01.22387.22387.3 1.27E-08 27/80 N.WITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 2344.2539 6.03 8790 22387 3 2344.256953 782.4253 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3978.6 - 2.94E+06 - - - 1.2895 - 3.672 0.649 - 627.3 1 1 0 0.003 21 0 0 0 2.94E+07 4.88E+06 - - - 8.8933 1 230117_WJC_METTL3_WT_vs_EV_F01.22388.22388.3 1.94E-05 15/52 K.FLTLPPVLHLQLMR.F "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1676.98 1.91 8791 22388 3 1676.982557 560.0006 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 9.76 3978.7 - 1.76E+06 - - - 1.5224 - 2.626 0.486 - 290.2 1 2 0 0.0026 14 0 0 0 7.34E+06 3.84E+06 - - - 6.5235 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.22389.22389.2 4.49E-06 14/22 K.IIDEDGLLNLIR[166.11].T "sp|P35251|RFC1_HUMAN,tr|H0Y8U4|H0Y8U4_HUMAN" 2 1392.7852 -1 8792 22389 2 1392.786107 697.3999 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 4.03 3978.8 - 1.68E+06 - - - 0.6512 - 2.382 0.274 - 555.2 1 2 0 0.0009 12 0 0 0 0.00E+00 0.00E+00 - - - 3.3482 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.22391.22391.2 0.00226 16-Jul K.EVWDYVFFK[136.11].E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PRP1|A0A6I8PRP1_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 1239.6056 -1 8794 22391 2 1239.603397 620.8101 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.37 3978.9 - 1.57E+06 - - - -1.7457 - 1.652 0.43 - 176.9 1 2 0 -0.0022 9 0 0 0 0.00E+00 0.00E+00 - - - 3.6686 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.22392.22392.2 0.328 16-Oct K.IAILGFAFK.K sp|O60701|UGDH_HUMAN 1 978.5902 -1 8795 22392 2 978.591347 490.3024 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 8.75 3979 - 1.46E+06 - - - 1.1322 - 2.219 0.358 - 269.7 1 2 0 0.0011 9 0 0 0 0.00E+00 0.00E+00 - - - 3.9908 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22394.22394.3 0.00553 14/52 K.FLTLPPVLHLQLMR[166.11].F "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1686.9883 -1 8797 22394 3 1686.991438 563.3367 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 9.76 3979.2 - 1.14E+06 - - - 1.8755 - 2.591 0.423 - 201.2 1 2 0 0.0032 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7852 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.22397.22397.2 0.0102 16-Sep K.IAILGFAFK[136.11].K sp|O60701|UGDH_HUMAN 1 986.6044 -1 8800 22397 2 986.604294 494.3095 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 8.75 3979.6 - 882193 - - - -0.147 - 2.047 0.308 - 176 1 2 0 -0.0001 9 0 0 0 0.00E+00 0.00E+00 - - - 3.3884 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.22398.22398.2 4.80E-06 22-Dec R.TEDFIIDTLELR[166.11].S sp|Q01780|EXOSX_HUMAN 1 1473.759 -1 8801 22398 2 1473.764676 737.8868 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 3.92 3979.7 - 842250 - - - 3.8208 - 2.484 0.422 - 618.7 1 2 0 0.0056 12 0 0 0 0.00E+00 0.00E+00 - - - 4.5501 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.22399.22399.2 0.00384 24-Nov R.VSELQVLLGYAGR.N "sp|O75925|PIAS1_HUMAN,tr|H3BSI8|H3BSI8_HUMAN" 2 1403.7773 -1 8802 22399 2 1403.778209 702.8959 E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=9606 GN=PIAS1 PE=1 SV=2 5.97 3979.8 - 757922 - - - 0.6725 - 2.129 0.25 - 336 1 2 0 0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 2.8266 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22404.22404.3 3.14E-05 14/56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 5.09 8806 22404 3 1591.946239 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3980.4 - 2.77E+06 - - - 0.7789 - 2.038 0.475 - 210.7 1 2 0 0.0012 15 0 0 0 1.88E+07 3.69E+06 - - - 5.6932 1 230117_WJC_METTL3_WT_vs_EV_F01.22405.22405.2 7.22E-09 13/28 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 5.52 8807 22405 2 1601.951481 801.9839 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3980.6 - 933897 - - - -1.1161 - 2.535 0.586 - 443.2 1 2 0 -0.0018 15 0 0 0 2.33E+07 4.23E+06 - - - 5.6556 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.22408.22408.2 0.599 18-Aug K.FLLFSSLVTK[136.11].E "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V686|A0A7I2V686_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 1161.6889 -1 8810 22408 2 1161.691226 581.8517 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 8.75 3980.8 - 1.44E+06 - - - 2.0048 - 1.587 0.237 - 122.8 1 2 0 0.0023 10 0 0 0 0.00E+00 0.00E+00 - - - 2.0799 1 230117_WJC_METTL3_WT_vs_EV_F01.22411.22411.3 1.42E-07 20/56 R.TVFRPPLDIYDVLIR.L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0C4DFX0|A0A0C4DFX0_HUMAN" 2 1816.0247 0.89 8813 22411 3 1816.023363 606.3488 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.63 3981 - 1.25E+06 - - - -0.7395 - 3.078 0.579 - 411.5 1 2 0 -0.0013 15 0 0 0 1.05E+07 1.18E+07 - - - 7.9286 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.22414.22414.3 0.000201 15/60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 1.2 8816 22414 3 1796.00522 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3981.3 - 860319 - - - 0.4766 - 2.564 0.348 - 394 1 2 0 0.0009 16 0 0 0 2.09E+06 1.74E+06 - - - 4.8356 1 230117_WJC_METTL3_WT_vs_EV_F01.22415.22415.2 0.00416 20-Dec R.YFGELLADLSR.K sp|Q8WVV4|POF1B_HUMAN 1 1282.6558 -1 8817 22415 2 1282.651636 642.3352 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 4.37 3981.4 - 822086 - - - -3.209 - 2.223 0.548 - 460.3 1 2 0 -0.0041 11 0 0 0 0.00E+00 0.00E+00 - - - 5.2483 0.9398 230117_WJC_METTL3_WT_vs_EV_F01.22422.22422.3 0.303 Sep-60 R.LLLLLGAAAAAASQTR[166.11].G sp|Q12849|GRSF1_HUMAN 1 1548.9227 -1 8824 22422 3 1548.927451 517.3148 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 9.75 3982.3 - 244227 - - - 3.0692 - 1.421 0.114 - 42.2 1 2 0 0.0048 16 0 0 0 0.00E+00 0.00E+00 - - - 0.7112 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.22426.22426.2 0.104 18-Dec R.ILGLLDAYLK[136.11].T sp|P26641|EF1G_HUMAN 1 1125.6889 0.89 8826 22426 2 1125.688439 563.8517 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3982.7 - 2.18E+07 - - - -0.4069 - 2.396 0.317 - 355.5 1 2 0 -0.0005 10 0 0 0 8.66E+07 9.68E+07 - - - 3.8213 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.22428.22428.2 0.0026 18-Oct R.ILGLLDAYLK.T sp|P26641|EF1G_HUMAN 1 1117.6747 0.89 8828 22428 2 1117.674748 559.8446 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3982.8 - 1.99E+07 - - - 0.0456 - 2.198 0.296 - 239.7 1 2 0 0.0001 10 0 0 0 8.66E+07 9.68E+07 - - - 3.4255 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22430.22430.3 4.61E-07 14/56 R.TVFR[166.11]PPLDIYDVLIR[166.11].L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0C4DFX0|A0A0C4DFX0_HUMAN" 2 1836.0412 0.88 8830 22430 3 1836.041069 613.021 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.63 3982.9 - 3.16E+06 - - - -0.0964 - 2.548 0.534 - 230.4 1 2 0 -0.0002 15 0 0 0 1.05E+07 1.20E+07 - - - 6.9341 0.9984 230117_WJC_METTL3_WT_vs_EV_F01.22431.22431.2 0.00216 20-Nov K.TFSFAIPLIER.L sp|Q9BQ39|DDX50_HUMAN 1 1292.7129 -1 8831 22431 2 1292.710506 647.3637 ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1 5.66 3982.9 - 3.01E+06 - - - -1.831 - 1.847 0.426 - 388.4 1 2 0 -0.0024 11 0 0 0 0.00E+00 0.00E+00 - - - 3.8465 1 230117_WJC_METTL3_WT_vs_EV_F01.22433.22433.2 1.03E-10 20/30 K.LPIVNEDDELVAIIAR.T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1778.9778 2.03 8833 22433 2 1778.975029 890.4962 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3983.1 - 2.67E+06 - - - -1.5661 - 3.893 0.688 - 1173.7 1 2 0 -0.0028 16 0 0 0 2.03E+07 1.00E+07 - - - 7.4633 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.22436.22436.3 1.63E-05 16/60 R.IPAEVLILNSIVLPHK.E "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 2 1755.0658 2.4 8836 22436 3 1755.064108 586.0292 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 6.75 3983.3 - 1.79E+06 - - - -0.988 - 3.084 0.361 - 355.4 1 2 0 -0.0017 16 0 0 0 7.18E+06 3.00E+06 - - - 5.4541 1 230117_WJC_METTL3_WT_vs_EV_F01.22437.22437.2 9.79E-13 19/30 K.LPIVNEDDELVAIIAR[166.11].T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1788.9861 2.03 8837 22437 2 1788.984153 895.5003 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3983.4 - 1.66E+06 - - - -1.0799 - 3.689 0.676 - 917.2 1 2 0 -0.0019 16 0 0 0 2.03E+07 1.00E+07 - - - 7.2426 0.999 230117_WJC_METTL3_WT_vs_EV_F01.22439.22439.3 0.00218 Aug-44 K.LIQLMEEIMAEK.E "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1446.7462 -1 8839 22439 3 1446.745936 483.256 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.25 3983.6 - 1.37E+06 - - - -0.1991 - 1.763 0.308 - 122 1 2 0 -0.0003 12 0 0 0 0.00E+00 0.00E+00 - - - 3.5455 0.9404 230117_WJC_METTL3_WT_vs_EV_F01.22441.22441.2 0.0726 14-Sep R.EC[160.03]LNLWGY.E sp|Q86U44|MTA70_HUMAN 1 1053.459 - 8841 22441 2 1053.458486 527.7368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3983.9 - 1.11E+06 - - - -0.4566 - 1.862 0.351 - 314.3 1 1 0 -0.0005 8 0 0 0 - - - - - 3.5082 0.9936 230117_WJC_METTL3_WT_vs_EV_F01.22444.22444.3 0.662 Aug-44 K.LIQLMEEIMAEK[136.11].E "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1454.7604 -1 8844 22444 3 1454.76108 485.9274 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.25 3984.2 - 953191 - - - 0.4509 - 1.832 0.161 - 87.4 2 2 0 0.0007 12 0 0 0 0.00E+00 0.00E+00 - - - 1.8736 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22445.22445.2 1.99E-05 18-Dec K.NIFAILQSVK.A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1131.6652 1.88 8845 22445 2 1131.667085 566.8399 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3984.4 - 871017 - - - 1.6701 - 2.121 0.34 - 317 1 2 0 0.0019 10 0 0 0 3.44E+07 1.83E+07 - - - 3.6504 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22447.22447.2 0.605 14/22 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 1.01 8846 22447 2 1344.865694 673.4385 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3984.6 - 4.65E+06 - - - 2.4159 - 2.427 0.373 - 677.2 1 2 0 0.0032 12 0 0 0 2.07E+08 2.04E+08 - - - 4.1279 0.9962 230117_WJC_METTL3_WT_vs_EV_F01.22448.22448.2 0.0141 15/22 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 1.01 8847 22448 2 1336.843607 669.4314 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3984.7 - 4.22E+06 - - - -3.4694 - 2.487 0.372 - 784.1 1 2 0 -0.0046 12 0 0 0 2.07E+08 2.04E+08 - - - 4.1843 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22450.22450.2 1.26 18-Oct K.NIFAILQSVK[136.11].A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1139.6794 -1 8849 22450 2 1139.680554 570.847 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3984.7 - 1.11E+07 - - - 1.017 - 2.049 0.326 - 231.1 1 2 0 0.0012 10 0 0 0 0.00E+00 0.00E+00 - - - 3.4508 1 230117_WJC_METTL3_WT_vs_EV_F01.22451.22451.3 1.64E-08 14/60 K.LPIVNEDDELVAIIAR.T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1778.9778 2.35 8850 22451 3 1778.980599 593.9999 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3984.8 - 8.10E+06 - - - 1.5649 - 2.921 0.589 - 241.8 1 2 0 0.0028 16 0 0 0 2.19E+07 9.30E+06 - - - 7.8564 1 230117_WJC_METTL3_WT_vs_EV_F01.22452.22452.2 4.28E-06 15/22 R.LGPLLDILADSR.H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1281.7293 1.49 8851 22452 2 1281.731788 641.8719 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3984.8 - 6.86E+06 - - - 1.9786 - 2.872 0.542 - 1026.9 1 2 0 0.0025 12 0 0 0 4.67E+07 3.13E+07 - - - 5.8193 1 230117_WJC_METTL3_WT_vs_EV_F01.22453.22453.2 7.24E-05 14/22 R.LGPLLDILADSR[166.11].H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1291.7375 1.49 8852 22453 2 1291.739257 646.876 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3984.9 - 4.72E+06 - - - 1.3432 - 2.896 0.457 - 841.7 1 2 0 0.0017 12 0 0 0 4.67E+07 3.13E+07 - - - 5.2137 0.9554 230117_WJC_METTL3_WT_vs_EV_F01.22454.22454.2 0.0019 14-Aug K.KEDLVFIF.W "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 1009.5484 2.38 8853 22454 2 1009.549282 505.7815 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.37 3985 - 4.00E+06 - - - 0.84 - 1.518 0.376 - 175.2 1 1 0 0.0008 8 0 0 0 8.29E+06 3.48E+06 - - - 3.0767 1 230117_WJC_METTL3_WT_vs_EV_F01.22455.22455.2 5.61E-07 14/22 K.VNFLPEIITLSK.E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1372.7966 -1 8854 22455 2 1372.799891 687.4056 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.97 3985 - 3.47E+06 - - - 2.3951 - 2.306 0.548 - 568.2 1 2 0 0.0033 12 0 0 0 0.00E+00 0.00E+00 - - - 5.2859 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22456.22456.3 1.14E-05 15/60 K.LPIVNEDDELVAIIAR[166.11].T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1788.9861 2.25 8855 22456 3 1788.988881 597.336 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3985.1 - 3.19E+06 - - - 1.5629 - 2.621 0.475 - 283.1 1 2 0 0.0028 16 0 0 0 2.19E+07 9.73E+06 - - - 6.3074 1 230117_WJC_METTL3_WT_vs_EV_F01.22460.22460.2 4.07E-07 24-Nov R.GNSIIMLEALERV.- "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1443.7756 -1 8859 22460 2 1443.777106 722.8951 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3985.5 - 2.03E+06 - - - 1.0777 - 2.613 0.503 - 478.4 1 2 0 0.0016 13 0 0 0 0.00E+00 0.00E+00 - - - 5.2208 1 230117_WJC_METTL3_WT_vs_EV_F01.22461.22461.2 3.02E-06 15/24 R.SDFFLEGPFMPPR.M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1538.7228 2.27 8860 22461 2 1538.724505 770.3687 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3985.6 - 1.97E+06 - - - 1.1172 - 2.974 0.566 - 722.7 1 2 0 0.0017 13 0 0 0 1.63E+07 7.16E+06 - - - 6.0182 0.9234 230117_WJC_METTL3_WT_vs_EV_F01.22463.22463.2 0.000276 20-Sep K.IIGINGDFFAN.M "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|F5H7Y1|F5H7Y1_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 4 1179.5924 - 8862 22463 2 1179.593644 590.8035 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 3.8 3985.8 - 1.27E+06 - - - 1.0343 - 1.772 0.24 - 171.2 1 1 0 0.0012 11 0 0 0 - - - - - 2.3609 1 230117_WJC_METTL3_WT_vs_EV_F01.22465.22465.2 1.20E-06 17/24 R.TDGALLVNAMFFK.P "sp|P50454|SERPH_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN" 6 1425.7326 -1 8864 22465 2 1425.725952 713.8736 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.5 3986.1 - 1.14E+06 - - - -4.679 - 2.909 0.484 - 1205.2 1 1 0 -0.0067 13 0 0 0 0.00E+00 0.00E+00 - - - 5.3543 1 230117_WJC_METTL3_WT_vs_EV_F01.22466.22466.2 3.07E-06 17/28 R.SILNADVAELLVVEK.D sp|Q8WVM0|TFB1M_HUMAN 1 1611.9083 -1 8865 22466 2 1611.913638 806.9614 "Dimethyladenosine transferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=TFB1M PE=1 SV=1" 4.14 3986.2 - 892862 - - - 3.288 - 3.447 0.545 - 842.6 1 2 0 0.0053 15 0 0 0 0.00E+00 0.00E+00 - - - 6.1072 0.971 230117_WJC_METTL3_WT_vs_EV_F01.22469.22469.2 1.38 24-Jun R.EYMSPDIALLYLK.H sp|Q7RTY7|OVCH1_HUMAN 1 1554.8004 4.3 8867 22469 2 1554.803859 778.4075 Ovochymase-1 OS=Homo sapiens OX=9606 GN=OVCH1 PE=2 SV=2 4.37 3986.6 - 1.58E+06 - - - 2.2453 - 0.998 0.115 - 69.1 1 2 0 0.0035 13 0 0 0 5.29E+06 1.23E+06 - - - -0.1158 1 230117_WJC_METTL3_WT_vs_EV_F01.22470.22470.2 1.10E-11 19/30 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 -1 8868 22470 2 1751.865582 876.9399 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3986.6 - 1.07E+07 - - - 0.2449 - 3.58 0.679 - 1143.2 1 2 0 0.0004 16 0 0 0 0.00E+00 0.00E+00 - - - 7.1915 1 230117_WJC_METTL3_WT_vs_EV_F01.22471.22471.3 0.000154 17/60 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 -1 8869 22471 3 1751.865557 584.9623 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3986.7 - 7.39E+06 - - - 0.2306 - 3.182 0.541 - 506.2 1 2 0 0.0004 16 0 0 0 0.00E+00 0.00E+00 - - - 7.5415 1 230117_WJC_METTL3_WT_vs_EV_F01.22472.22472.2 3.73E-09 14/30 K.VGEVTYVELLMDAEGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1759.8794 -1 8870 22472 2 1759.880069 880.947 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3986.7 - 4.77E+06 - - - 0.4068 - 3.092 0.665 - 493.2 1 2 0 0.0007 16 0 0 0 0.00E+00 0.00E+00 - - - 6.7277 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.22473.22473.3 1.41E-05 17/44 K.LR[166.11]EC[160.03]LPLIIFLR[166.11].N sp|P62701|RS4X_HUMAN 1 1561.9281 0.94 8871 22473 3 1561.928584 521.65 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3986.8 - 4.45E+06 - - - 0.2907 - 2.885 0.49 - 572.9 1 2 1 0.0005 12 0 0 0 7.31E+07 7.80E+07 - - - 6.9397 1 230117_WJC_METTL3_WT_vs_EV_F01.22474.22474.3 1.02E-06 15/44 K.LREC[160.03]LPLIIFLR.N sp|P62701|RS4X_HUMAN 1 1541.9116 0.94 8872 22474 3 1541.911508 514.9778 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3986.8 - 4.16E+06 - - - -0.0532 - 2.908 0.589 - 486 1 2 1 -0.0001 12 0 0 0 7.31E+07 7.80E+07 - - - 8.0656 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22475.22475.3 1.33E-07 13/60 K.VGEVTYVELLMDAEGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1759.8794 -1 8873 22475 3 1759.878983 587.6337 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3986.9 - 2.91E+06 - - - -0.2102 - 2.713 0.539 - 247.4 1 2 0 -0.0004 16 0 0 0 0.00E+00 0.00E+00 - - - 7.1101 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22477.22477.3 4.20E-05 15/44 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 1.01 8875 22477 3 1336.847804 446.6234 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3987 - 2.28E+06 - - - -0.3299 - 2.535 0.528 - 306.6 1 2 0 -0.0004 12 0 0 0 1.80E+07 1.79E+07 - - - 7.0049 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22479.22479.3 4.34E-06 15/44 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 1.01 8877 22479 3 1344.862627 449.2948 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3987.1 - 2.22E+06 - - - 0.1353 - 2.665 0.499 - 304.2 1 2 0 0.0002 12 0 0 0 1.80E+07 1.79E+07 - - - 6.8203 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22480.22480.3 5.36E-06 13/44 R.LFVWEILHSTIR[166.11].K "sp|Q09161|NCBP1_HUMAN,tr|X6R941|X6R941_HUMAN" 2 1522.8536 -1 8878 22480 3 1522.853994 508.6251 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 6.75 3987.1 - 2.02E+06 - - - 0.2883 - 2.425 0.399 - 219.9 1 2 0 0.0004 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4437 1 230117_WJC_METTL3_WT_vs_EV_F01.22482.22482.2 0.0027 18-Dec K.LASDLLEWIR.R "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|G3V2W4|G3V2W4_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 14 1214.6659 -1 8880 22482 2 1214.665001 608.3402 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.37 3987.3 - 1.87E+06 - - - -0.7591 - 2.575 0.422 - 550 1 2 0 -0.0009 10 0 0 0 0.00E+00 0.00E+00 - - - 4.7978 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.22483.22483.2 0.0327 20-Oct R.FLIPVLNGLEK[136.11].K "sp|Q92797|SYMPK_HUMAN,tr|A0A087WUE9|A0A087WUE9_HUMAN" 2 1249.7526 -1 8881 22483 2 1249.755463 625.8836 Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2 6 3987.4 - 1.55E+06 - - - 2.3229 - 1.629 0.276 - 311.9 1 2 0 0.0029 11 0 0 0 0.00E+00 0.00E+00 - - - 2.3987 0.9966 230117_WJC_METTL3_WT_vs_EV_F01.22485.22485.2 0.0199 16-Sep R.MDLFSALIK.G "sp|Q9C0C9|UBE2O_HUMAN,tr|K7ES11|K7ES11_HUMAN" 2 1036.5627 1.29 8883 22485 2 1036.566546 519.2886 (E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3 5.59 3987.5 - 1.39E+06 - - - 3.7065 - 1.557 0.255 - 141 1 2 0 0.0038 9 0 0 0 4.59E+06 3.55E+06 - - - 2.2042 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.22487.22487.2 0.000501 16-Oct R.QLYLPMLFK[136.11].V "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN" 13 1159.6555 -1 8885 22487 2 1159.655445 580.835 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3987.7 - 900185 - - - -0.0371 - 1.718 0.451 - 272.6 1 2 0 0 9 0 0 0 0.00E+00 0.00E+00 - - - 3.9377 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.22490.22490.3 0.00838 Aug-44 R.LGPLLDILADSR[166.11].H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1291.7375 -1 8887 22490 3 1291.736099 431.5865 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3988 - 387533 - - - -1.1016 - 1.656 0.332 - 95.8 1 2 0 -0.0014 12 0 0 0 0.00E+00 0.00E+00 - - - 3.6392 1 230117_WJC_METTL3_WT_vs_EV_F01.22492.22492.2 5.14E-06 13/22 R.YLDFSSIITEVR.A sp|Q8N1N4|K2C78_HUMAN 1 1441.7453 -1 8889 22492 2 1441.746272 721.8799 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.37 3988.1 - 5.05E+06 - - - 0.677 - 2.592 0.598 - 589 1 2 0 0.001 12 0 0 0 0.00E+00 0.00E+00 - - - 5.9635 1 230117_WJC_METTL3_WT_vs_EV_F01.22493.22493.2 4.87E-06 18/28 K.LGLLGLANSLAIEGR.K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1495.8722 -1 8890 22493 2 1495.873107 748.9434 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3988.2 - 3.76E+06 - - - 0.5876 - 3.7 0.537 - 1175.3 1 2 0 0.0009 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2236 1 230117_WJC_METTL3_WT_vs_EV_F01.22494.22494.2 0.000418 13/22 K.SVEELLEAELLK.V "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 1371.7497 -1 8891 22494 2 1371.749868 686.8821 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.09 3988.2 - 3.67E+06 - - - 0.113 - 2.638 0.443 - 478.7 1 2 0 0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 4.8652 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.22495.22495.2 0.065 20-Oct K.LGELPSWILMR[166.11].D "sp|P56134|ATPK_HUMAN,tr|G3V325|G3V325_HUMAN,tr|C9JU26|C9JU26_HUMAN,tr|C9JJT5|C9JJT5_HUMAN" 4 1323.7248 -1 8892 22495 2 1323.728943 662.8697 "ATP synthase subunit f, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MF PE=1 SV=3" 6 3988.3 - 2.73E+06 - - - 3.0928 - 1.859 0.375 - 265.6 1 2 0 0.0041 11 0 0 0 0.00E+00 0.00E+00 - - - 3.4868 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22496.22496.2 0.000187 18-Sep K.VLVYELLLGK.G sp|Q96P11|NSUN5_HUMAN 1 1145.706 1.7 8893 22496 2 1145.707211 573.8603 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 5.97 3988.4 - 2.27E+06 - - - 1.0596 - 1.882 0.385 - 238 1 2 0 0.0012 10 0 0 0 8.37E+06 4.93E+06 - - - 3.6493 1 230117_WJC_METTL3_WT_vs_EV_F01.22497.22497.2 3.58E-05 16/28 K.LGLLGLANSLAIEGR[166.11].K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1505.8805 -1 8894 22497 2 1505.881852 753.9475 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3988.5 - 1.66E+06 - - - 0.8991 - 3.234 0.583 - 984.3 1 2 0 0.0014 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2323 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22498.22498.3 0.000342 17/56 K.LGLLGLANSLAIEGR.K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1495.8722 -1 8895 22498 3 1495.871588 499.6314 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3988.6 - 1.63E+06 - - - -0.4278 - 2.716 0.432 - 245.6 1 2 0 -0.0006 15 0 0 0 0.00E+00 0.00E+00 - - - 5.9634 0.9555 230117_WJC_METTL3_WT_vs_EV_F01.22499.22499.2 0.0209 18-Aug K.VLVYELLLGK[136.11].G sp|Q96P11|NSUN5_HUMAN 1 1153.7202 -1 8896 22499 2 1153.725657 577.8674 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 5.97 3988.6 - 1.63E+06 - - - 4.7325 - 1.608 0.055 - 148.3 2 2 0 0.0055 10 0 0 0 0.00E+00 0.00E+00 - - - 0.6369 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22500.22500.3 0.000305 Dec-44 K.SVEELLEAELLK.V "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 1371.7497 3 8897 22500 3 1371.749995 458.2572 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.09 3988.7 - 1.43E+06 - - - 0.2056 - 2.256 0.302 - 312.4 1 2 0 0.0003 12 0 0 0 3.53E+06 1.18E+06 - - - 4.1621 0.9967 230117_WJC_METTL3_WT_vs_EV_F01.22502.22502.2 0.00605 26-Sep R.LLQSPC[160.03]PFC[160.03]DSPVF.- sp|Q9UKN8|TF3C4_HUMAN 1 1665.7531 - 8899 22502 2 1665.756495 833.8838 General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2 3.8 3989 - 1.21E+06 - - - 2.0375 - 1.278 0.235 - 135.1 1 2 0 0.0034 14 0 0 0 - - - - - 1.3912 0.9979 230117_WJC_METTL3_WT_vs_EV_F01.22503.22503.3 0.109 Jul-44 R.YLDFSSIITEVR.A sp|Q8N1N4|K2C78_HUMAN 1 1441.7453 -1 8900 22503 3 1441.745909 481.589 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.37 3989.1 - 1.15E+06 - - - 0.4252 - 1.501 0.271 - 84.8 1 2 0 0.0006 12 0 0 0 0.00E+00 0.00E+00 - - - 2.6869 1 230117_WJC_METTL3_WT_vs_EV_F01.22504.22504.2 1.60E-07 13/24 R.SDFFLEGPFMPPR[166.11].M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1548.7311 2.43 8901 22504 2 1548.734456 775.3728 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3989.2 - 1.00E+06 - - - 2.1953 - 2.413 0.508 - 462.2 1 2 0 0.0034 13 0 0 0 1.62E+07 6.65E+06 - - - 5.0528 0.9948 230117_WJC_METTL3_WT_vs_EV_F01.22508.22508.2 0.0687 26-Jun R.ALVENC[160.03]LVPDLWIR.Y "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 1696.8971 -1 8905 22508 2 1696.895904 849.4558 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.37 3989.7 - 866625 - - - -0.683 - 1.278 0.261 - 69.2 1 2 0 -0.0012 14 0 0 0 0.00E+00 0.00E+00 - - - 1.5839 1 230117_WJC_METTL3_WT_vs_EV_F01.22511.22511.2 3.71E-17 24/38 K.MLLDPMGGIVMTNDGNAILR.E "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 2130.0636 -1 8907 22511 2 2130.065435 1066.0391 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.21 3990 - 3.74E+06 - - - 0.884 - 4.112 0.723 - 1742.9 1 2 0 0.0019 20 0 0 0 0.00E+00 0.00E+00 - - - 7.8566 1 230117_WJC_METTL3_WT_vs_EV_F01.22515.22515.2 1.45E-05 20-Dec K.TLSYLLPLLQR[166.11].L sp|Q9NUL7|DDX28_HUMAN 1 1325.7946 1.03 8911 22515 2 1325.795472 663.9046 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3990.2 - 6.65E+06 - - - 0.6253 - 2.046 0.54 - 485.3 1 2 0 0.0008 11 0 0 0 2.66E+07 2.59E+07 - - - 4.9658 1 230117_WJC_METTL3_WT_vs_EV_F01.22516.22516.3 7.73E-09 16/52 R.LLNNAFEELVAFQR.A "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1662.873 -1 8912 22516 3 1662.872811 555.2983 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.53 3990.3 - 6.54E+06 - - - -0.0872 - 2.869 0.561 - 318.1 1 2 0 -0.0001 14 0 0 0 0.00E+00 0.00E+00 - - - 7.5955 1 230117_WJC_METTL3_WT_vs_EV_F01.22517.22517.2 2.04E-05 13/20 K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 1.03 8913 22517 2 1315.786824 658.9005 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3990.3 - 5.44E+06 - - - 0.3428 - 2.145 0.608 - 613.9 1 2 0 0.0005 11 0 0 0 2.66E+07 2.59E+07 - - - 5.596 0.8975 230117_WJC_METTL3_WT_vs_EV_F01.22519.22519.2 0.024 18-Jul E.QEEDISSLIR.S sp|P78527|PRKDC_HUMAN 1 1188.5986 7.37 8915 22519 2 1188.598819 595.3066 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.14 3990.4 - 4.72E+06 - - - 0.1573 - 1.414 0.314 - 121.8 1 1 0 0.0002 10 0 0 0 4.80E+07 6.52E+06 - - - 2.3271 1 230117_WJC_METTL3_WT_vs_EV_F01.22521.22521.2 1.01E-07 14/26 R.LLNNAFEELVAFQR.A "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1662.873 -1 8917 22521 2 1662.86856 832.4438 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.53 3990.5 - 3.94E+06 - - - -2.6436 - 3.027 0.592 - 793 1 2 0 -0.0044 14 0 0 0 0.00E+00 0.00E+00 - - - 6.1915 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.22522.22522.2 0.0011 18-Nov K.LNMILVQILK.Q "sp|O14980|XPO1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 1183.7363 -1 8918 22522 2 1183.736596 592.8754 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3990.6 - 2.87E+06 - - - 0.2915 - 2.309 0.401 - 447.5 1 2 0 0.0003 10 0 0 0 0.00E+00 0.00E+00 - - - 4.3385 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22525.22525.3 1.04E-05 Oct-48 K.GIVSEEAYILFVR.K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1494.8082 0.99 8921 22525 3 1494.807871 499.2767 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.53 3990.7 - 2.22E+06 - - - -0.2402 - 1.793 0.501 - 54.3 1 2 0 -0.0004 13 0 0 0 6.23E+06 6.27E+06 - - - 5.7086 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.22526.22526.2 0.000201 20-Sep K.EYPFILDAFQR.E sp|P42285|MTREX_HUMAN 1 1397.698 0.97 8922 22526 2 1397.697181 699.8563 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 3990.8 - 2.21E+06 - - - -0.5516 - 1.731 0.433 - 292.2 1 2 0 -0.0008 11 0 0 0 1.06E+07 1.09E+07 - - - 3.7233 0.9393 230117_WJC_METTL3_WT_vs_EV_F01.22527.22527.2 0.000778 22-Nov K.LR[166.11]EC[160.03]LPLIIFLR[166.11].N sp|P62701|RS4X_HUMAN 1 1561.9281 -1 8923 22527 2 1561.929231 781.9713 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3990.9 - 2.03E+06 - - - 0.7049 - 2.293 0.406 - 112.9 1 2 1 0.0011 12 0 0 0 0.00E+00 0.00E+00 - - - 4.2229 1 230117_WJC_METTL3_WT_vs_EV_F01.22528.22528.2 9.73E-08 16/22 K.LREC[160.03]LPLIIFLR.N sp|P62701|RS4X_HUMAN 1 1541.9116 -1 8924 22528 2 1541.911994 771.9631 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3991 - 2.00E+06 - - - 0.262 - 3.228 0.602 - 324.2 1 2 1 0.0004 12 0 0 0 0.00E+00 0.00E+00 - - - 6.5706 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.22529.22529.3 1.81E-05 13/40 K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 1.05 8925 22529 3 1315.78578 439.6027 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3991.1 - 1.49E+06 - - - -0.4507 - 2.255 0.38 - 323.1 1 2 0 -0.0006 11 0 0 0 4.44E+06 4.25E+06 - - - 5.0865 1 230117_WJC_METTL3_WT_vs_EV_F01.22532.22532.2 4.03E-09 16/28 K.GVFVQSVLPYFVATK.L "sp|Q53GQ0|DHB12_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN" 2 1653.913 -1 8927 22532 2 1653.914035 827.9638 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 8.59 3991.5 - 5.31E+06 - - - 0.6076 - 2.754 0.603 - 632.1 1 2 0 0.001 15 0 0 0 0.00E+00 0.00E+00 - - - 5.9851 1 230117_WJC_METTL3_WT_vs_EV_F01.22533.22533.2 2.54E-08 18/28 R.LPFLSSSNLSLDVLR.G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1659.9196 -1 8928 22533 2 1659.919948 830.9671 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3991.6 - 2.70E+07 - - - 0.2265 - 3.571 0.577 - 1174.7 1 2 0 0.0004 15 0 0 0 0.00E+00 0.00E+00 - - - 6.432 1 230117_WJC_METTL3_WT_vs_EV_F01.22534.22534.2 7.38E-06 22-Dec R.NLQNLLILTAIK[136.11].A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1360.8533 0.99 8929 22534 2 1360.85396 681.4339 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3991.6 - 2.09E+07 - - - 0.4578 - 2.501 0.535 - 437.8 1 2 0 0.0006 12 0 0 0 5.77E+07 5.84E+07 - - - 5.4043 1 230117_WJC_METTL3_WT_vs_EV_F01.22535.22535.2 3.18E-06 13/22 R.NLQNLLILTAIK.A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1352.8391 -1 8930 22535 2 1352.839364 677.4268 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3991.6 - 2.08E+07 - - - 0.1678 - 2.581 0.571 - 516.4 1 2 0 0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 5.7531 1 230117_WJC_METTL3_WT_vs_EV_F01.22536.22536.2 3.67E-08 17/28 R.LPFLSSSNLSLDVLR[166.11].G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1669.9278 -1 8931 22536 2 1669.927945 835.9712 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3991.7 - 1.93E+07 - - - 0.0617 - 3.397 0.645 - 940.1 1 2 0 0.0001 15 0 0 0 0.00E+00 0.00E+00 - - - 6.8115 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.22539.22539.2 0.166 13/24 K.GIVSEEAYILFVR.K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1494.8082 1.12 8934 22539 2 1494.80775 748.4114 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.53 3991.8 - 4.51E+06 - - - -0.3211 - 2.324 0.348 - 423.7 1 2 0 -0.0005 13 0 0 0 1.39E+07 1.24E+07 - - - 3.7755 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.22540.22540.2 0.00801 18-Oct K.LNMILVQILK[136.11].Q "sp|O14980|XPO1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 1191.7505 -1 8935 22540 2 1191.752673 596.8825 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3991.9 - 4.33E+06 - - - 1.8645 - 1.821 0.298 - 233.7 1 2 0 0.0022 10 0 0 0 0.00E+00 0.00E+00 - - - 2.9144 0.9939 230117_WJC_METTL3_WT_vs_EV_F01.22543.22543.2 0.265 22-Oct K.IILNTAVAEFFK.S "sp|Q9H9A5|CNO10_HUMAN,tr|H7C1X9|H7C1X9_HUMAN" 2 1364.7704 -1 8938 22543 2 1364.771095 683.3925 CCR4-NOT transcription complex subunit 10 OS=Homo sapiens OX=9606 GN=CNOT10 PE=1 SV=1 6 3992.1 - 7.01E+06 - - - 0.518 - 1.459 0.122 - 161.1 1 2 0 0.0007 12 0 0 0 0.00E+00 0.00E+00 - - - 0.9358 0.9989 230117_WJC_METTL3_WT_vs_EV_F01.22544.22544.2 0.000464 20-Oct K.EYPFILDAFQR[166.11].E sp|P42285|MTREX_HUMAN 1 1407.7062 1.02 8939 22544 2 1407.704469 704.8604 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 3992.2 - 2.71E+06 - - - -1.2453 - 1.819 0.439 - 392.1 1 2 0 -0.0018 11 0 0 0 1.12E+07 1.11E+07 - - - 3.9014 1 230117_WJC_METTL3_WT_vs_EV_F01.22545.22545.2 3.17E-11 21/32 K.LFEMVLGPAAYNVPLPK.K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1858.0063 2.01 8940 22545 2 1858.0108 930.0104 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6 3992.3 - 2.70E+06 - - - 2.4338 - 3.898 0.632 - 1533.2 1 2 0 0.0045 17 0 0 0 1.04E+07 5.16E+06 - - - 7.0523 1 230117_WJC_METTL3_WT_vs_EV_F01.22546.22546.2 1.77E-08 15/24 K.GNLEVLLFTIQSK.L "sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 5 1460.8239 -1 8941 22546 2 1460.827112 731.4192 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6 3992.4 - 2.56E+06 - - - 2.2118 - 3.065 0.565 - 1053.8 1 2 0 0.0032 13 0 0 0 0.00E+00 0.00E+00 - - - 6.0877 1 230117_WJC_METTL3_WT_vs_EV_F01.22547.22547.2 2.12E-07 17/22 K.LGTLSALDILIK.N "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1255.7751 -1 8942 22547 2 1255.774781 628.8948 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 5.84 3992.5 - 2.46E+06 - - - -0.2851 - 3.235 0.53 - 1403.1 1 2 0 -0.0004 12 0 0 0 0.00E+00 0.00E+00 - - - 6.0445 1 230117_WJC_METTL3_WT_vs_EV_F01.22548.22548.2 2.08E-08 16/26 R.ISLPLPNFSSLNLR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1569.8879 1.65 8943 22548 2 1569.889493 785.9512 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3992.6 - 2.31E+06 - - - 1.0287 - 2.656 0.554 - 673.3 1 2 0 0.0016 14 0 0 0 1.64E+07 9.97E+06 - - - 5.5836 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22549.22549.3 4.43E-05 Dec-44 R.NLQNLLILTAIK.A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1352.8391 -1 8944 22549 3 1352.838321 451.9537 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3992.7 - 2.21E+06 - - - -0.6032 - 2.53 0.442 - 358.6 1 2 0 -0.0008 12 0 0 0 0.00E+00 0.00E+00 - - - 6.0405 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.22550.22550.3 2.59E-05 Dec-60 R.FLLPEYLPYAGIFHER.G "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1964.0196 -1 8945 22550 3 1964.023171 655.6805 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 5.4 3992.8 - 2.16E+06 - - - 1.808 - 1.883 0.426 - 140.2 1 2 0 0.0036 16 0 0 0 0.00E+00 0.00E+00 - - - 4.9123 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.22552.22552.2 0.000881 18-Aug R.SPNDLLALFR.Y "sp|Q92626|PXDN_HUMAN,tr|H7C1W1|H7C1W1_HUMAN" 2 1144.6241 0.18 8946 22552 2 1144.624925 573.3193 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 5.55 3993 - 512037 - - - 0.7575 - 1.793 0.357 - 105.9 1 2 0 0.0009 10 0 0 0 7.79E+06 4.43E+07 - - - 3.3073 1 230117_WJC_METTL3_WT_vs_EV_F01.22553.22553.2 8.62E-06 26-Nov K.LPVDFSNIPTYLLK.D "sp|Q9NXR7|BABA2_HUMAN,tr|F8W733|F8W733_HUMAN" 2 1618.897 -1 8947 22553 2 1618.896566 810.4558 BRISC and BRCA1-A complex member 2 OS=Homo sapiens OX=9606 GN=BABAM2 PE=1 SV=2 5.83 3993.1 - 706521 - - - -0.2959 - 2.231 0.501 - 174.3 1 2 0 -0.0005 14 0 0 0 0.00E+00 0.00E+00 - - - 4.7549 1 230117_WJC_METTL3_WT_vs_EV_F01.22554.22554.2 3.04E-07 16/26 R.VISGVLQLGNIVFK[136.11].K sp|P35579|MYH9_HUMAN 1 1493.9061 -1 8948 22554 2 1493.906246 747.9603 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.72 3993.1 - 1.41E+07 - - - 0.0971 - 3.189 0.631 - 717.9 1 2 0 0.0001 14 0 0 0 0.00E+00 0.00E+00 - - - 6.6117 1 230117_WJC_METTL3_WT_vs_EV_F01.22555.22555.3 2.05E-07 13/64 R.AFLQGGQEATDIALLLR.D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1814.989 -1 8949 22555 3 1814.989788 606.0036 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3993.2 - 9.24E+06 - - - 0.4077 - 2.847 0.547 - 239.2 1 2 0 0.0007 17 0 0 0 0.00E+00 0.00E+00 - - - 7.2815 0.8986 230117_WJC_METTL3_WT_vs_EV_F01.22556.22556.2 0.0495 18-Jun K.VEDLTFTSPF.C "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1154.5496 - 8950 22556 2 1154.550145 578.2821 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 3.67 3993.2 - 9.00E+06 - - - 0.5102 - 1.251 0.341 - 100.9 1 1 0 0.0006 10 0 0 0 - - - - - 2.1845 1 230117_WJC_METTL3_WT_vs_EV_F01.22557.22557.2 3.91E-09 19/32 R.AFLQGGQEATDIALLLR.D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1814.989 -1 8951 22557 2 1814.990619 908.5018 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3993.3 - 5.56E+06 - - - 0.8656 - 3.596 0.677 - 1195.6 1 2 0 0.0016 17 0 0 0 0.00E+00 0.00E+00 - - - 7.1873 1 230117_WJC_METTL3_WT_vs_EV_F01.22558.22558.2 4.75E-05 13/22 K.LGTLSALDILIK[136.11].N "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1263.7893 -1 8952 22558 2 1263.789607 632.9019 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 5.84 3993.3 - 5.48E+06 - - - 0.2121 - 2.628 0.51 - 609 1 2 0 0.0003 12 0 0 0 0.00E+00 0.00E+00 - - - 5.3501 1 230117_WJC_METTL3_WT_vs_EV_F01.22563.22563.3 2.04E-08 19/60 K.IFEIFGPVAHPFYVLR.F sp|Q96HR8|NAF1_HUMAN 1 1904.0349 -1 8957 22563 3 1904.036848 635.6856 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 6.75 3993.6 - 3.14E+06 - - - 1.0357 - 3.653 0.565 - 513.4 1 2 0 0.002 16 0 0 0 0.00E+00 0.00E+00 - - - 8.1628 1 230117_WJC_METTL3_WT_vs_EV_F01.22565.22565.3 0.000438 18/72 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 8959 22565 3 1911.181487 638.0676 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3993.7 - 2.70E+06 - - - 0.3218 - 3.272 0.517 - 462.7 1 2 0 0.0006 19 0 0 0 0.00E+00 0.00E+00 - - - 7.2162 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22566.22566.2 2.84E-06 28-Sep K.LTILQSLGDPLYYGK.L "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 1679.9134 -1 8960 22566 2 1679.913952 840.964 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.83 3993.8 - 2.65E+06 - - - 0.3143 - 2.113 0.43 - 242.6 1 2 0 0.0005 15 0 0 0 0.00E+00 0.00E+00 - - - 4.0561 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22567.22567.3 1.45E-06 Sep-44 K.TSDLIVLGLPWK.T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1340.7704 -1 8961 22567 3 1340.770804 447.9307 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3993.8 - 2.37E+06 - - - 0.3103 - 1.799 0.526 - 116.8 1 2 0 0.0004 12 0 0 0 0.00E+00 0.00E+00 - - - 6.032 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.22569.22569.2 2.25E-05 24-Nov K.GNLEVLLFTIQSK[136.11].L "sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 5 1468.8381 0.98 8963 22569 2 1468.839927 735.4263 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6 3994 - 2.24E+06 - - - 1.2568 - 2.142 0.427 - 450.5 1 2 0 0.0018 13 0 0 0 6.82E+06 6.95E+06 - - - 4.1493 1 230117_WJC_METTL3_WT_vs_EV_F01.22570.22570.2 0.00669 15/36 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 8964 22570 2 1911.181662 956.5977 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3994.1 - 2.02E+06 - - - 0.4134 - 2.585 0.451 - 481.4 1 2 0 0.0008 19 0 0 0 0.00E+00 0.00E+00 - - - 4.7068 1 230117_WJC_METTL3_WT_vs_EV_F01.22571.22571.2 1.05E-10 15/32 R.AFLQGGQEATDIALLLR[166.11].D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1824.9973 -1 8965 22571 2 1824.995225 913.5059 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3994.1 - 2.00E+06 - - - -1.1469 - 3.232 0.673 - 766.2 1 2 0 -0.0021 17 0 0 0 0.00E+00 0.00E+00 - - - 6.8952 1 230117_WJC_METTL3_WT_vs_EV_F01.22573.22573.2 1.18E-05 15/26 R.ISLPLPNFSSLNLR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1579.8961 1.65 8966 22573 2 1579.896534 790.9554 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3994.4 - 1.14E+06 - - - 0.2443 - 2.191 0.503 - 575.7 1 2 0 0.0004 14 0 0 0 1.64E+07 9.97E+06 - - - 4.7243 1 230117_WJC_METTL3_WT_vs_EV_F01.22578.22578.2 5.86E-08 22-Dec K.TSDLIVLGLPWK.T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1340.7704 2.43 8971 22578 2 1340.772328 671.3925 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3994.6 - 5.78E+06 - - - 1.4469 - 2.521 0.598 - 543.7 1 2 0 0.0019 12 0 0 0 9.88E+07 4.07E+07 - - - 5.8901 0.9144 230117_WJC_METTL3_WT_vs_EV_F01.22580.22580.2 1.97 18-Apr R.C[160.03]FSTTLLYC[160.03]R.K sp|P60893|GPR85_HUMAN 1 1319.6002 999 8973 22580 2 1319.597988 660.8074 Probable G-protein coupled receptor 85 OS=Homo sapiens OX=9606 GN=GPR85 PE=1 SV=1 8.06 3994.7 - 4.87E+06 - - - -1.6982 - 1.098 0.117 - 41.8 3 2 0 -0.0022 10 0 0 0 2.35E+07 0.00E+00 - - - -0.0477 1 230117_WJC_METTL3_WT_vs_EV_F01.22583.22583.2 1.09E-05 13/20 R.VLDLVEVLVTK[136.11].Q "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1234.7628 -1 8976 22583 2 1234.764225 618.3887 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.37 3994.8 - 2.56E+06 - - - 1.1622 - 2.702 0.565 - 527.3 1 2 0 0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 5.9026 1 230117_WJC_METTL3_WT_vs_EV_F01.22584.22584.2 4.59E-05 18-Oct K.FDTIYQILLK.K "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 1252.7067 2.97 8977 22584 2 1252.706544 627.3606 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 5.83 3994.9 - 2.27E+06 - - - -0.1445 - 1.981 0.493 - 305.3 1 2 0 -0.0002 10 0 0 0 1.25E+07 4.20E+06 - - - 4.5904 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22587.22587.2 0.000734 22-Nov R.SQALIEELLLYK.R sp|Q5VT52|RPRD2_HUMAN 1 1418.8021 -1 8980 22587 2 1418.804726 710.4083 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3995.1 - 1.92E+06 - - - 1.8635 - 2.291 0.344 - 296.9 1 2 0 0.0026 12 0 0 0 0.00E+00 0.00E+00 - - - 3.7622 1 230117_WJC_METTL3_WT_vs_EV_F01.22588.22588.3 3.71E-10 16/52 R.HPYFYAPELLFFAK.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 1741.8868 -1 8981 22588 3 1741.889052 581.6362 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6.75 3995.1 - 1.78E+06 - - - 1.2842 - 3.175 0.624 - 475 1 2 0 0.0022 14 0 0 0 0.00E+00 0.00E+00 - - - 8.5666 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.22589.22589.2 0.000901 14/20 R.VLDLVEVLVTK.Q "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1226.7486 -1 8982 22589 2 1226.750756 614.3816 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.37 3995.2 - 1.77E+06 - - - 1.7656 - 1.586 0.442 - 347.5 1 2 0 0.0022 11 0 0 0 0.00E+00 0.00E+00 - - - 3.5526 0.9971 230117_WJC_METTL3_WT_vs_EV_F01.22590.22590.2 0.0496 22-Aug K.NVLITDFFGSVR.K "sp|Q92643|GPI8_HUMAN,tr|B1AK81|B1AK81_HUMAN,tr|A6NEM5|A6NEM5_HUMAN" 3 1366.7245 2.09 8983 22590 2 1366.728183 684.3695 GPI-anchor transamidase OS=Homo sapiens OX=9606 GN=PIGK PE=1 SV=2 5.84 3995.2 - 1.70E+06 - - - 2.694 - 1.564 0.211 - 129.3 1 2 0 0.0037 12 0 0 0 6.74E+06 3.22E+06 - - - 1.7751 0.9988 230117_WJC_METTL3_WT_vs_EV_F01.22591.22591.2 0.00423 18-Aug K.EFEPLLNWMK[136.11].D "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 1313.6569 -1 8984 22591 2 1313.656747 657.8357 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 4.53 3995.3 - 1.58E+06 - - - -0.1507 - 1.601 0.317 - 252.1 1 2 0 -0.0002 10 0 0 0 0.00E+00 0.00E+00 - - - 2.696 1 230117_WJC_METTL3_WT_vs_EV_F01.22594.22594.2 8.84E-08 16/24 R.DPTYFGPVLNYLR[166.11].H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1563.7961 0.8 8986 22594 2 1563.800916 782.9053 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3995.7 - 2.22E+06 - - - 3.0803 - 2.889 0.659 - 981.3 1 2 0 0.0048 13 0 0 0 8.96E+06 1.12E+07 - - - 6.6297 1 230117_WJC_METTL3_WT_vs_EV_F01.22597.22597.2 2.55E-12 17/26 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 -1 8989 22597 2 1537.76812 769.8922 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3995.9 - 8.69E+06 - - - -1.0899 - 3.246 0.721 - 888.9 1 2 0 -0.0017 14 0 0 0 0.00E+00 0.00E+00 - - - 7.3205 1 230117_WJC_METTL3_WT_vs_EV_F01.22598.22598.2 4.92E-07 22-Dec K.FFDDPMLLELAK.Q "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1437.7214 -1 8990 22598 2 1437.721335 719.868 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.03 3995.9 - 5.28E+06 - - - -0.0376 - 2.457 0.554 - 216 1 2 0 -0.0001 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4981 1 230117_WJC_METTL3_WT_vs_EV_F01.22601.22601.2 1.38E-05 15/26 K.TLAESALQLLYTAK.E sp|Q9Y490|TLN1_HUMAN 1 1520.845 -1 8993 22601 2 1520.847439 761.4298 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.66 3996.1 - 2.08E+06 - - - 1.5971 - 2.46 0.477 - 509.4 1 2 0 0.0024 14 0 0 0 0.00E+00 0.00E+00 - - - 4.8223 0.9952 230117_WJC_METTL3_WT_vs_EV_F01.22602.22602.2 3.92E-08 16/26 K.DAAGIAMEAIAFAR.N sp|P08240|SRPRA_HUMAN 1 1405.7024 -1 8994 22602 2 1405.711343 703.8585 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 4.37 3996.1 - 2.05E+06 - - - 6.3726 - 2.896 0.363 - 902.4 1 2 0 0.009 14 0 0 0 0.00E+00 0.00E+00 - - - 4.3877 1 230117_WJC_METTL3_WT_vs_EV_F01.22603.22603.2 1.20E-07 16/28 R.ATSFLLALEPELEAR[166.11].L "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1668.8962 -1 8995 22603 2 1668.898278 835.4554 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.25 3996.2 - 2.05E+06 - - - 1.2409 - 3.21 0.559 - 852.1 1 2 0 0.0021 15 0 0 0 0.00E+00 0.00E+00 - - - 6.0365 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.22604.22604.3 0.000607 Dec-48 R.GNTAAYLLYAFTR.L sp|P54136|SYRC_HUMAN 1 1459.746 -1 8996 22604 3 1459.746729 487.5893 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.59 3996.3 - 1.89E+06 - - - 0.5234 - 1.862 0.302 - 162.7 1 2 0 0.0008 13 0 0 0 0.00E+00 0.00E+00 - - - 3.5923 1 230117_WJC_METTL3_WT_vs_EV_F01.22605.22605.2 1.14E-07 14/26 K.TLAESALQLLYTAK[136.11].E sp|Q9Y490|TLN1_HUMAN 1 1528.8592 -1 8997 22605 2 1528.861888 765.4369 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.66 3996.3 - 1.81E+06 - - - 1.7516 - 2.436 0.481 - 449.5 1 2 0 0.0027 14 0 0 0 0.00E+00 0.00E+00 - - - 4.8271 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.22606.22606.3 0.000523 15/56 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 -1 8998 22606 3 1519.910011 507.6435 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3996.4 - 1.66E+06 - - - 0.9198 - 2.396 0.363 - 257.2 1 2 0 0.0014 15 0 0 0 0.00E+00 0.00E+00 - - - 4.8668 1 230117_WJC_METTL3_WT_vs_EV_F01.22608.22608.3 9.25E-08 18/52 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 4.4 9000 22608 3 1537.770656 513.5972 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3996.5 - 1.62E+06 - - - 0.5593 - 3.217 0.595 - 578.4 1 2 0 0.0009 14 0 0 0 1.58E+07 3.60E+06 - - - 8.2786 0.9998 230117_WJC_METTL3_WT_vs_EV_F01.22611.22611.3 0.00177 13/68 R.LDSVLLLSSMNLPGGELR.R "sp|Q13868|EXOS2_HUMAN,tr|A3KFL1|A3KFL1_HUMAN,tr|A3KFL2|A3KFL2_HUMAN,tr|A3KFL5|A3KFL5_HUMAN" 4 1913.0292 2.35 9003 22611 3 1913.03356 638.6837 Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2 4.37 3996.8 - 1.25E+06 - - - 2.2796 - 2.433 0.348 - 152.8 1 2 0 0.0044 18 0 0 0 4.40E+06 1.87E+06 - - - 4.6327 0.9909 230117_WJC_METTL3_WT_vs_EV_F01.22612.22612.2 0.18 22-Nov K.FVFFNIPQIQYK[136.11].N "sp|P82663|RT25_HUMAN,tr|E7EPW2|E7EPW2_HUMAN" 2 1550.8377 -1 9004 22612 2 1550.841762 776.4261 "28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1" 8.59 3996.9 - 1.22E+06 - - - 2.6276 - 1.432 0.113 - 212.3 1 2 0 0.0041 12 0 0 0 0.00E+00 0.00E+00 - - - 0.8191 1 230117_WJC_METTL3_WT_vs_EV_F01.22613.22613.3 5.64E-10 18/72 R.LPVVIGGLLDVDC[160.03]SEDVIK.N "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2040.0813 -1 9005 22613 3 2040.085604 681.0344 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 3.84 3997.1 - 1.17E+06 - - - 2.1127 - 3.64 0.6 - 592.8 1 2 0 0.0043 19 0 0 0 0.00E+00 0.00E+00 - - - 8.4024 1 230117_WJC_METTL3_WT_vs_EV_F01.22617.22617.2 5.76E-05 14/26 K.DMLEAGILDTYLGK[136.11].Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1545.784 -1 9008 22617 2 1545.785022 773.8993 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3997.4 - 4.93E+06 - - - 0.6637 - 2.886 0.569 - 516.5 1 2 0 0.001 14 0 0 0 0.00E+00 0.00E+00 - - - 5.903 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.22619.22619.3 0.00173 13/52 K.ILGGSVLHLVLALR.G sp|Q15843|NEDD8_HUMAN 1 1459.9239 -1 9010 22619 3 1459.925028 487.6486 NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1 9.76 3997.5 - 4.00E+06 - - - 0.7939 - 2.306 0.435 - 254.8 1 2 0 0.0012 14 0 0 0 0.00E+00 0.00E+00 - - - 5.6099 1 230117_WJC_METTL3_WT_vs_EV_F01.22620.22620.2 3.06E-06 22-Dec K.AYVVLGQFLVLK[136.11].K sp|O75531|BAF_HUMAN 1 1356.8261 -1 9011 22620 2 1356.828378 679.4203 Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1 8.63 3997.5 - 2.73E+06 - - - 1.7091 - 2.504 0.551 - 470.4 1 2 0 0.0023 12 0 0 0 0.00E+00 0.00E+00 - - - 5.5251 1 230117_WJC_METTL3_WT_vs_EV_F01.22621.22621.2 1.16E-06 15/22 K.AILC[160.03]LLLGGVER.D "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1312.7537 -1 9012 22621 2 1312.756017 657.3841 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 6.04 3997.5 - 2.45E+06 - - - 1.7703 - 2.6 0.513 - 1198.9 1 2 0 0.0023 12 0 0 0 0.00E+00 0.00E+00 - - - 5.3434 1 230117_WJC_METTL3_WT_vs_EV_F01.22622.22622.2 7.47E-07 22-Sep K.NTPFLYDLVMTH.A "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|E9PIC4|E9PIC4_HUMAN,tr|E9PNS2|E9PNS2_HUMAN,tr|E9PNS6|E9PNS6_HUMAN,tr|C9JAJ9|C9JAJ9_HUMAN,tr|E9PC52|E9PC52_HUMAN" 7 1449.6962 - 9013 22622 2 1449.697254 725.8554 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.08 3997.6 - 2.44E+06 - - - 0.7015 - 2.25 0.608 - 288.6 1 1 0 0.001 12 0 0 0 - - - - - 5.6651 1 230117_WJC_METTL3_WT_vs_EV_F01.22624.22624.3 7.95E-07 21/52 K.ILGGSVLHLVLALR[166.11].G sp|Q15843|NEDD8_HUMAN 1 1469.9321 -1 9015 22624 3 1469.933014 490.9847 NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1 9.76 3997.7 - 2.21E+06 - - - 0.5953 - 3.077 0.59 - 770.6 1 2 0 0.0009 14 0 0 0 0.00E+00 0.00E+00 - - - 8.1046 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.22625.22625.2 0.00972 28-Nov R.ATSFLLALEPELEAR.L "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1658.8879 -1 9016 22625 2 1658.889613 830.4512 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.25 3997.7 - 2.16E+06 - - - 1.0103 - 2.071 0.456 - 246.4 1 2 0 0.0017 15 0 0 0 0.00E+00 0.00E+00 - - - 4.1984 1 230117_WJC_METTL3_WT_vs_EV_F01.22626.22626.2 2.73E-08 20/28 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 -1 9017 22626 2 1519.910063 760.9616 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3997.8 - 1.78E+06 - - - 0.954 - 3.161 0.568 - 1692.6 1 2 0 0.0014 15 0 0 0 0.00E+00 0.00E+00 - - - 6.0653 1 230117_WJC_METTL3_WT_vs_EV_F01.22628.22628.2 1.19E-06 22-Dec K.AYVVLGQFLVLK.K sp|O75531|BAF_HUMAN 1 1348.8119 -1 9019 22628 2 1348.814309 675.4132 Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1 8.63 3997.9 - 1.59E+06 - - - 1.8164 - 2.335 0.58 - 461.4 1 2 0 0.0024 12 0 0 0 0.00E+00 0.00E+00 - - - 5.5554 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.22629.22629.3 0.0223 13/56 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 -1 9020 22629 3 1529.917135 510.9796 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3998 - 1.58E+06 - - - 0.1647 - 2.221 0.361 - 170 1 2 0 0.0003 15 0 0 0 0.00E+00 0.00E+00 - - - 4.6469 1 230117_WJC_METTL3_WT_vs_EV_F01.22631.22631.2 1.60E-06 14/24 R.LLDEWFTLDEVPK.G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1603.8134 -1 9022 22631 2 1603.817898 802.914 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 3.92 3998.2 - 1.10E+06 - - - 2.8202 - 2.458 0.475 - 602.1 1 2 0 0.0045 13 0 0 0 0.00E+00 0.00E+00 - - - 4.8561 1 230117_WJC_METTL3_WT_vs_EV_F01.22632.22632.2 1.39E-07 17/28 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 -1 9023 22632 2 1529.923482 765.9657 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3998.2 - 949267 - - - 4.3133 - 2.979 0.612 - 816 1 2 0 0.0066 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2429 0.9943 230117_WJC_METTL3_WT_vs_EV_F01.22633.22633.3 0.0151 Oct-52 K.DMLEAGILDTYLGK[136.11].Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1545.784 -1 9024 22633 3 1545.784809 516.2686 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3998.3 - 943447 - - - 0.5259 - 1.48 0.211 - 84.1 1 2 0 0.0008 14 0 0 0 0.00E+00 0.00E+00 - - - 1.9341 0.9991 230117_WJC_METTL3_WT_vs_EV_F01.22638.22638.2 0.0557 16-Jul K.LLLPWLEAR.L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1109.6597 -1 9028 22638 2 1109.661197 555.8371 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6 3998.7 - 9.19E+06 - - - 1.3346 - 1.559 0.301 - 242 1 2 0 0.0015 9 0 0 0 0.00E+00 0.00E+00 - - - 2.5484 1 230117_WJC_METTL3_WT_vs_EV_F01.22640.22640.2 5.72E-05 14/20 K.GIVLLEELLPK.G sp|Q9Y3D6|FIS1_HUMAN 1 1222.7537 -1 9030 22640 2 1222.754935 612.3841 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 4.53 3998.8 - 2.34E+06 - - - 1.0296 - 2.565 0.517 - 789.1 1 2 0 0.0013 11 0 0 0 0.00E+00 0.00E+00 - - - 5.4074 1 230117_WJC_METTL3_WT_vs_EV_F01.22642.22642.3 1.85E-05 15/44 K.FFEVILIDPFHK[136.11].A "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 4 1511.8268 -1 9032 22642 3 1511.828631 504.9495 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 5.32 3999 - 2.07E+06 - - - 1.2191 - 2.538 0.488 - 231.8 1 2 0 0.0018 12 0 0 0 0.00E+00 0.00E+00 - - - 6.5618 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.22643.22643.2 0.0208 18-Jul K.DAVIEFLLDK.S "sp|Q9BY42|RTF2_HUMAN,tr|A0A0A0MQR2|A0A0A0MQR2_HUMAN,tr|A2A2L6|A2A2L6_HUMAN,tr|A2A2L5|A2A2L5_HUMAN" 4 1161.6281 -1 9033 22643 2 1161.630643 581.8213 Replication termination factor 2 OS=Homo sapiens OX=9606 GN=RTF2 PE=1 SV=3 4.03 3999.1 - 1.72E+06 - - - 2.1539 - 1.583 0.263 - 99.2 1 2 0 0.0025 10 0 0 0 0.00E+00 0.00E+00 - - - 2.2648 1 230117_WJC_METTL3_WT_vs_EV_F01.22647.22647.2 8.90E-06 24-Nov K.LVDQNIFSFYLSR.D "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1600.8249 -1 9037 22647 2 1600.82403 801.4197 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.84 3999.4 - 1.51E+06 - - - -0.5703 - 2.175 0.488 - 287.1 1 2 0 -0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 4.6393 0.9947 230117_WJC_METTL3_WT_vs_EV_F01.22648.22648.3 0.00751 21/80 K.IAGAGLLFVGGGIGGTILYAK[136.11].W "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1955.1335 -1 9038 22648 3 1955.128362 652.7185 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.59 3999.5 - 1.50E+06 - - - -2.6453 - 2.926 0.207 - 425.7 1 2 0 -0.0052 21 0 0 0 0.00E+00 0.00E+00 - - - 3.4204 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.23266.23266.2 0.00504 16-Aug R.IAIYELLFK[136.11].E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1116.6674 1.39 9068 23266 2 1116.668903 559.341 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4120.7 - 58142.4 - - - 1.3164 - 1.83 0.385 - 159.4 1 2 0 0.0015 9 0 0 0 1.44E+08 1.04E+08 - - - 3.6325 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.23268.23268.3 0.000906 15/52 R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 3.69 9069 23268 3 1486.872638 496.6312 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4120.9 - 298122 - - - 0.5011 - 2.701 0.482 - 289 1 2 0 0.0007 14 0 0 0 7.93E+06 2.15E+06 - - - 6.5542 1 230117_WJC_METTL3_WT_vs_EV_F01.23269.23269.2 0.0019 16/26 R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 12.57 9070 23269 2 1486.876355 744.4432 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4121.1 - 185609 - - - 3.0009 - 2.872 0.52 - 942.8 1 2 0 0.0045 14 0 0 0 8.07E+06 6.42E+05 - - - 5.5278 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.23270.23270.2 0.0206 14/16 R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.39 9071 23270 2 1108.655684 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4121.2 - 1.37E+06 - - - 2.2108 - 2.404 0.277 - 423.9 1 2 0 0.0025 9 0 0 0 1.44E+08 1.04E+08 - - - 3.6237 0.999 230117_WJC_METTL3_WT_vs_EV_F01.23278.23278.2 0.0105 20-Sep K.TVLQELINVLK[136.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1276.7846 -1 9079 23278 2 1276.787426 639.3996 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.66 4122.2 - 152327 - - - 2.2228 - 1.704 0.279 - 208.9 1 2 0 0.0028 11 0 0 0 0.00E+00 0.00E+00 - - - 2.5426 1 230117_WJC_METTL3_WT_vs_EV_F01.23280.23280.3 3.91E-05 15/52 K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.84 9081 23280 3 1618.969173 540.6625 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4122.5 - 127958 - - - 2.0871 - 2.716 0.494 - 231.3 1 2 0 0.0034 14 0 0 0 1.47E+07 7.99E+06 - - - 6.702 1 230117_WJC_METTL3_WT_vs_EV_F01.23281.23281.2 1.05E-06 16/26 K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.53 9082 23281 2 1618.971279 810.4902 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4122.6 - 127823 - - - 3.388 - 2.538 0.564 - 472.5 1 2 0 0.0055 14 0 0 0 3.49E+07 2.28E+07 - - - 5.5422 1 230117_WJC_METTL3_WT_vs_EV_F01.23282.23282.2 1.23E-10 19/28 R.LTSFIGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1516.8865 7.71 9083 23282 2 1516.889208 759.4505 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 4122.8 - 122186 - - - 1.7978 - 3.254 0.624 - 1088.2 1 2 0 0.0027 15 0 0 0 2.17E+07 2.82E+06 - - - 6.5498 1 230117_WJC_METTL3_WT_vs_EV_F01.23285.23285.3 1.97E-06 31/56 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 6.19 9086 23285 3 1581.912763 528.3103 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4123.1 - 107562 - - - 2.3743 - 4.586 0.596 - 1956.1 1 2 0 0.0038 15 0 0 0 4.55E+07 7.35E+06 - - - 9.1579 1 230117_WJC_METTL3_WT_vs_EV_F01.23287.23287.2 1.91E-06 16/26 K.ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1626.98 1.53 9088 23287 2 1626.982353 814.4973 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4123.4 - 86067.3 - - - 1.4499 - 2.496 0.501 - 523.5 1 2 0 0.0024 14 0 0 0 3.49E+07 2.28E+07 - - - 5.036 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.23292.23292.3 0.000343 13/56 R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 -1 9092 23292 3 1555.900099 519.6409 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 4123.8 - 3.76E+07 - - - -0.419 - 2.634 0.419 - 164.7 1 2 0 -0.0007 15 0 0 0 0.00E+00 0.00E+00 - - - 5.7384 1 230117_WJC_METTL3_WT_vs_EV_F01.23293.23293.2 0.157 17/28 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 7.69 9093 23293 2 1581.907789 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4123.8 - 2.95E+07 - - - -0.77 - 3.499 0.536 - 1154.5 1 2 0 -0.0012 15 0 0 0 5.27E+07 6.85E+06 - - - 6.0788 1 230117_WJC_METTL3_WT_vs_EV_F01.23295.23295.2 7.71E-06 14/30 K.LGFAGLVQEISFGTTK.D "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1666.893 6.31 9095 23295 2 1666.891744 834.4538 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 4123.9 - 9.70E+06 - - - -0.7673 - 2.995 0.606 - 496.4 1 2 0 -0.0013 16 0 0 0 1.89E+07 2.99E+06 - - - 6.2134 0.9997 230117_WJC_METTL3_WT_vs_EV_F01.23298.23298.3 0.000121 Oct-52 K.ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1626.98 1.84 9098 23298 3 1626.978917 543.3339 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4124 - 7.10E+06 - - - -0.662 - 1.78 0.453 - 137.7 1 2 0 -0.0011 14 0 0 0 1.47E+07 7.99E+06 - - - 5.1226 1 230117_WJC_METTL3_WT_vs_EV_F01.23300.23300.2 5.84E-05 26-Aug R.APIASIHSFELDLL.- sp|Q13015|AF1Q_HUMAN 1 1524.8188 - 9100 23300 2 1524.816414 763.4167 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 4.35 4124.1 - 5.03E+06 - - - -1.5615 - 1.942 0.528 - 181.2 1 2 0 -0.0024 14 0 0 0 - - - - - 4.6056 1 230117_WJC_METTL3_WT_vs_EV_F01.23301.23301.2 4.62E-05 15/28 R.QVLLSAAEAAEVILR[166.11].V sp|P78371|TCPB_HUMAN 1 1591.9173 -1 9101 23301 2 1591.911206 796.9659 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4124.2 - 3.96E+06 - - - -3.8136 - 3.23 0.519 - 851.5 1 2 0 -0.0061 15 0 0 0 0.00E+00 0.00E+00 - - - 5.755 0.9939 230117_WJC_METTL3_WT_vs_EV_F01.23302.23302.3 1.19 Jun-56 R.LTSFIGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1516.8865 7.63 9102 23302 3 1516.885423 506.6361 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 4124.2 - 3.36E+06 - - - -0.6975 - 1.447 0.255 - 59.8 1 2 0 -0.0011 15 0 0 0 4.92E+06 6.44E+05 - - - 2.3468 1 230117_WJC_METTL3_WT_vs_EV_F01.23304.23304.2 5.09E-07 14/24 K.SLEEIYLFSLPIK[136.11].E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN,tr|H3BNG3|H3BNG3_HUMAN,tr|H0YE27|H0YE27_HUMAN" 7 1558.8738 0.55 9104 23304 2 1558.872008 780.4442 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.53 4124.3 - 3.27E+06 - - - -1.1476 - 2.827 0.569 - 565.7 1 2 0 -0.0018 13 0 0 0 3.58E+06 6.54E+06 - - - 5.9103 1 230117_WJC_METTL3_WT_vs_EV_F01.23306.23306.2 1.80E-07 26-Dec R.LLVPTQFVGAIIGK[136.11].E "sp|O00425|IF2B3_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 3 1462.9003 -1 9106 23306 2 1462.900071 732.4574 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 4124.5 - 2.75E+06 - - - -0.1477 - 2.515 0.58 - 353.3 1 2 0 -0.0002 14 0 0 0 0.00E+00 0.00E+00 - - - 5.6392 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.23307.23307.2 0.00268 22-Jun R.TFC[160.03]QLILDPIFK.V sp|P13639|EF2_HUMAN 1 1493.7952 -1 9107 23307 2 1493.797149 747.9049 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.5 4124.5 - 2.47E+06 - - - 1.2893 - 1.442 0.445 - 107.3 1 2 0 0.0019 12 0 0 0 0.00E+00 0.00E+00 - - - 3.2903 0.9994 230117_WJC_METTL3_WT_vs_EV_F01.23310.23310.2 0.000665 22-Sep R.LLTSFLPAQLLR.L "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|H0YFX4|H0YFX4_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 14 1370.8286 -1 9109 23310 2 1370.828257 686.4216 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 9.75 4124.8 - 391046 - - - -0.2298 - 1.806 0.448 - 218.2 1 2 0 -0.0003 12 0 0 0 0.00E+00 0.00E+00 - - - 3.9052 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.23312.23312.2 0.00834 13/20 K.GIVLLEELLPK.G sp|Q9Y3D6|FIS1_HUMAN 1 1222.7537 1.94 9111 23312 2 1222.757504 612.3841 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 4.53 4125.1 - 961892 - - - 3.1306 - 2.332 0.42 - 640.9 1 2 0 0.0038 11 0 0 0 3.73E+06 1.92E+06 - - - 4.4325 1 230117_WJC_METTL3_WT_vs_EV_F01.23314.23314.2 5.31E-06 26-Dec R.DYLHLPPEIVPATL.H "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1576.8501 - 9113 23314 2 1576.854224 789.4323 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.35 4125.4 - 631246 - - - 2.6185 - 2.062 0.557 - 452.5 1 1 0 0.0041 14 0 0 0 - - - - - 4.9697 1 230117_WJC_METTL3_WT_vs_EV_F01.23315.23315.2 3.95E-10 16/32 R.WVGGPEIELIAIATGGR.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1737.9414 20.98 9114 23315 2 1737.945166 869.978 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 4125.5 - 626480 - - - 2.1842 - 2.862 0.604 - 579.9 1 2 0 0.0038 17 0 0 0 2.93E+06 1.40E+05 - - - 6.0862 0.9992 230117_WJC_METTL3_WT_vs_EV_F01.23316.23316.2 0.00905 20-Aug K.GIVLLEELLPK[136.11].G sp|Q9Y3D6|FIS1_HUMAN 1 1230.7679 -1 9115 23316 2 1230.770913 616.3912 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 4.53 4125.6 - 563447 - - - 2.4676 - 1.788 0.32 - 189.5 1 2 0 0.003 11 0 0 0 0.00E+00 0.00E+00 - - - 2.9756 0.9986 230117_WJC_METTL3_WT_vs_EV_F01.23317.23317.3 0.00994 Nov-52 R.LISQIVSSITASLR[166.11].F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1496.8802 3.69 9116 23317 3 1496.887914 499.9673 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4125.7 - 554541 - - - 5.1781 - 1.922 0.395 - 187.3 1 2 0 0.0077 14 0 0 0 7.93E+06 2.15E+06 - - - 4.6781 1 230117_WJC_METTL3_WT_vs_EV_F01.23318.23318.2 3.54E-08 30-Dec K.LGFAGLVQEISFGTTK[136.11].D "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1674.9072 -1 9117 23318 2 1674.909735 838.4609 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 4125.9 - 446966 - - - 1.4998 - 2.963 0.551 - 306 1 2 0 0.0025 16 0 0 0 0.00E+00 0.00E+00 - - - 5.7804 0.9925 230117_WJC_METTL3_WT_vs_EV_F01.23319.23319.2 0.00333 18-Aug R.C[160.03]WAGSLWLFK[136.11].D sp|Q9BQA1|MEP50_HUMAN 1 1274.6362 0.33 9118 23319 2 1274.642473 638.3254 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 4126 - 438189 - - - 4.9606 - 1.391 0.315 - 211.9 1 2 0 0.0063 10 0 0 0 1.13E+06 3.40E+06 - - - 2.2868 1 230117_WJC_METTL3_WT_vs_EV_F01.23321.23321.2 9.23E-08 13/28 K.FDVILLEPPLEEYYR.E "sp|Q9HCE5|MET14_HUMAN,tr|D6RBL4|D6RBL4_HUMAN" 2 1894.9717 999 9120 23321 2 1894.974526 948.4931 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4 4126.3 - 360040 - - - 1.5087 - 2.549 0.612 - 388.8 1 2 0 0.0029 15 0 0 0 2.10E+06 0.00E+00 - - - 5.8608 0.9995 230117_WJC_METTL3_WT_vs_EV_F01.23322.23322.2 0.000445 24-Aug R.DLYEDELVPLFEK.A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1608.7923 2.18 9121 23322 2 1608.794242 805.4034 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 4126.4 - 326008 - - - 1.2034 - 1.447 0.444 - 153.8 1 2 0 0.0019 13 0 0 0 2.41E+06 1.11E+06 - - - 3.2681 0.9977 230117_WJC_METTL3_WT_vs_EV_F01.23328.23328.2 0.00847 26-May K.VWINTSDIILVGLR.D "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 3 1597.9192 1.12 9126 23328 2 1597.924791 799.9669 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 5.81 4127.2 - 255660 - - - 3.5127 - 1.239 0.391 - 65.2 1 2 0 0.0056 14 0 0 0 1.68E+06 1.50E+06 - - - 2.465 1 230117_WJC_METTL3_WT_vs_EV_F01.23358.23358.2 2.16E-07 14/32 R.AQLGVQAFADALLIIPK.V sp|P40227|TCPZ_HUMAN 1 1767.0295 -1 9134 23358 2 1767.041711 884.522 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.88 4132.2 - 227345 - - - 6.9348 - 3.208 0.609 - 417.3 1 2 0 0.0123 17 0 0 0 0.00E+00 0.00E+00 - - - 6.401 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.23471.23471.2 0.0336 16-Nov R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.86 9151 23471 2 1108.654351 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4152.4 - 373416 - - - 1.0084 - 2.359 0.283 - 318.3 1 2 0 0.0011 9 0 0 0 9.27E+06 4.98E+06 - - - 3.6138 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.23474.23474.2 3.22E-06 26-Oct K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.57 9152 23474 2 1618.970081 810.4902 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4152.8 - 0 - - - 2.648 - 2.068 0.443 - 209 1 2 0 0.0043 14 0 0 0 3.16E+06 2.01E+06 - - - 4.135 0.9987 230117_WJC_METTL3_WT_vs_EV_F01.23477.23477.2 0.000258 28-Jul R.LTSFIGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1516.8865 10.87 9154 23477 2 1516.889564 759.4505 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 4153.1 - 64487.4 - - - 2.0325 - 1.709 0.255 - 128.7 1 2 0 0.0031 15 0 0 0 1.73E+06 1.60E+05 - - - 2.241 0.9999 230117_WJC_METTL3_WT_vs_EV_F01.23479.23479.3 0.00385 Oct-56 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 8.66 9155 23479 3 1581.91103 528.3103 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4153.4 - 117632 - - - 1.2788 - 2.296 0.455 - 190.4 1 2 0 0.002 15 0 0 0 3.46E+06 3.99E+05 - - - 5.7811 1 230117_WJC_METTL3_WT_vs_EV_F01.23486.23486.2 0.00271 15/28 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 10.12 9157 23486 2 1581.911541 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4154.3 - 0 - - - 1.6019 - 3.093 0.603 - 919.5 1 2 0 0.0025 15 0 0 0 5.09E+06 5.03E+05 - - - 6.27 0.9996 230117_WJC_METTL3_WT_vs_EV_F01.23511.23511.2 0.000297 26-Jul R.APIASIHSFELDLL.- sp|Q13015|AF1Q_HUMAN 1 1524.8188 - 9160 23511 2 1524.821073 763.4167 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 4.35 4158.8 - 15998.6 - - - 1.4939 - 1.453 0.515 - 145.2 1 2 0 0.0023 14 0 0 0 - - - - - 3.7817 0.981 230117_WJC_METTL3_WT_vs_EV_F01.23642.23642.2 0.661 22-Mar R.LLTSFLPAQLLR.L "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|H0YFX4|H0YFX4_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 14 1370.8286 1.31 9178 23642 2 1370.833612 686.4216 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 9.75 4182 - 9492.8 - - - 3.6766 - 0.879 0.277 - 27.9 1 2 0 0.005 12 0 0 0 5.88E+05 4.48E+05 - - - 0.746 0.9993 230117_WJC_METTL3_WT_vs_EV_F01.23644.23644.2 0.00894 16-Sep R.IAIYELLFK[136.11].E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1116.6674 1.49 9179 23644 2 1116.670408 559.341 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4182.3 - 290149 - - - 2.6642 - 2.109 0.277 - 227 1 2 0 0.003 9 0 0 0 3.23E+07 2.17E+07 - - - 3.2448 0.9985 230117_WJC_METTL3_WT_vs_EV_F01.23646.23646.2 0.0247 16-Jun R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.49 9180 23646 2 1108.655786 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4182.5 - 32043.7 - - - 2.3028 - 1.454 0.285 - 84.9 1 2 0 0.0026 9 0 0 0 3.18E+07 2.13E+07 - - - 2.2281 0.9893 230117_WJC_METTL3_WT_vs_EV_F01.23650.23650.2 0.206 26-May K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.54 9182 23650 2 1618.96988 810.4902 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4183 - 7035.59 - - - 2.5238 - 1.074 0.195 - 45.7 1 2 0 0.0041 14 0 0 0 1.33E+07 8.64E+06 - - - 0.6591 0.999 230117_WJC_METTL3_WT_vs_EV_F01.23656.23656.3 0.0951 Jun-56 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 6.6 9185 23656 3 1581.912622 528.3103 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4183.8 - 13886 - - - 2.2852 - 1.349 0.36 - 54.5 1 2 0 0.0036 15 0 0 0 1.94E+07 2.94E+06 - - - 3.3338 1 230117_WJC_METTL3_WT_vs_EV_F01.23661.23661.2 0.00889 13/28 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 8.37 9186 23661 2 1581.913107 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4184.7 - 7142.42 - - - 2.5918 - 2.817 0.573 - 622.9 1 2 0 0.0041 15 0 0 0 1.50E+07 1.79E+06 - - - 5.8181 0.9753 230117_WJC_METTL3_WT_vs_EV_F01.23667.23667.2 1.57 26-Mar R.LLVPTQFVGAIIGK[136.11].E "sp|O00425|IF2B3_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 3 1462.9003 1.3 9189 23667 2 1462.905223 732.4574 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 4185.5 - 15710.7 - - - 3.3741 - 0.712 0.302 - 28.8 1 2 0 0.0049 14 0 0 0 1.24E+06 9.54E+05 - - - 0.4176 0.8708 230117_WJC_METTL3_WT_vs_EV_F02.03618.03618.2 20.2 12-Apr K.LAEQAER.Y "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|I3L0W5|I3L0W5_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB1|A2IDB1_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|F8WEB6|F8WEB6_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 22 815.4137 2.6 9216 3618 2 815.413683 408.7141 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.53 1400.7 - 108488 - - - -0.0589 - 0.942 0.042 - 47.7 2 2 0 0 7 0 0 0 1.83E+06 7.06E+05 - - - -0.9726 0.8571 230117_WJC_METTL3_WT_vs_EV_F02.03638.03638.2 3.36 14-May K.SFATASHR.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 875.425 0.72 9218 3638 2 875.423029 438.7198 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.49 1404.1 - 29667.5 - - - -2.2115 - 0.94 0.127 - 73.1 1 2 0 -0.0019 8 0 0 0 1.69E+06 2.33E+06 - - - -0.2082 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.04117.04117.2 0.00588 12-Aug K.TSQVPVK[136.11].H sp|Q9NXV2|KCTD5_HUMAN 1 765.4476 0.03 9229 4117 2 765.448158 383.7311 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.41 1490.2 - 624106 - - - 0.7238 - 1.737 0.262 - 350.6 1 2 0 0.0006 7 0 0 0 4.16E+05 1.45E+07 - - - 2.7255 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.04118.04118.2 0.0382 12-Jul R.NSTIPTK.Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 759.4127 9.45 9230 4118 2 759.413295 380.7136 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 1490.3 - 453506 - - - 0.8243 - 1.438 0.259 - 218.8 1 2 0 0.0006 7 0 0 0 2.43E+07 2.57E+06 - - - 2.1048 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.04150.04150.2 0.0011 18-Oct R.IAGQVAAANK.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 941.5294 1.52 9234 4150 2 941.529828 471.772 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1495.8 - 384244 - - - 0.4227 - 2.015 0.292 - 260.5 1 2 0 0.0004 10 0 0 0 1.23E+07 8.08E+06 - - - 3.1532 0.9929 230117_WJC_METTL3_WT_vs_EV_F02.04225.04225.2 0.0028 14-Jul R.NTEEEGLK[136.11].Y "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 926.4436 1.4 9236 4225 2 926.440775 464.2291 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.25 1509.2 - 233953 - - - -3.0936 - 1.41 0.368 - 179.4 1 2 0 -0.0029 8 0 0 0 3.00E+07 2.14E+07 - - - 2.7944 0.9895 230117_WJC_METTL3_WT_vs_EV_F02.04253.04253.2 0.478 12-Jul R.EAQVNVR[166.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 824.438 0.05 9237 4253 2 824.437568 413.2263 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1514.1 - 702679 - - - -0.507 - 1.341 0.13 - 248.3 1 2 0 -0.0004 7 0 0 0 1.42E+07 2.69E+08 - - - 0.9308 0.9938 230117_WJC_METTL3_WT_vs_EV_F02.04258.04258.2 0.112 12-Jul R.EAQVNVR.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 814.4297 0.05 9238 4258 2 814.429238 408.2221 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1514.8 - 586466 - - - -0.5869 - 1.17 0.25 - 274.7 1 2 0 -0.0005 7 0 0 0 1.43E+07 2.70E+08 - - - 1.3848 0.8583 230117_WJC_METTL3_WT_vs_EV_F02.04438.04438.2 3.51 12-May K.EQSIVEK.F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 831.4338 860.84 9247 4438 2 831.432522 416.7242 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 1546.2 - 2.73E+07 - - - -1.5347 - 1.172 0.016 - 167.5 2 2 0 -0.0013 7 0 0 0 7.56E+08 8.78E+05 - - - -0.4728 0.9842 230117_WJC_METTL3_WT_vs_EV_F02.04511.04511.2 0.112 16-May K.VLENAEGAR.T "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 957.488 17.73 9250 4511 2 957.485653 479.7513 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.53 1558.8 - 148097 - - - -2.4084 - 1.036 0.327 - 86.2 1 2 0 -0.0023 9 0 0 0 5.06E+06 2.85E+05 - - - 1.5578 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.04529.04529.2 0.016 14-Jun K.SVLADQGK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 816.4341 0.47 9252 4529 2 816.434489 409.2243 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.55 1561.8 - 1.86E+07 - - - 0.4373 - 1.283 0.326 - 95.4 1 2 0 0.0004 8 0 0 0 3.11E+07 6.58E+07 - - - 2.2003 0.988 230117_WJC_METTL3_WT_vs_EV_F02.05043.05043.2 0.391 16-Jul K.TIAPQNAPR[166.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 976.5329 0.15 9261 5043 2 976.534461 489.2738 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1654.7 - 826108 - - - 1.5483 - 1.16 0.119 - 87.8 1 2 0 0.0015 9 0 0 0 2.62E+07 1.76E+08 - - - 0.3488 0.9953 230117_WJC_METTL3_WT_vs_EV_F02.05521.05521.2 2.55 12-Jul K.ITITNDK.G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 803.4389 12.89 9275 5521 2 803.440585 402.7267 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1739.7 - 457844 - - - 2.1184 - 1.3 0.17 - 174.4 1 2 0 0.0017 7 0 0 0 1.20E+08 9.32E+06 - - - 1.1274 0.9832 230117_WJC_METTL3_WT_vs_EV_F02.05530.05530.2 8.64 12-May K.ITITNDK[136.11].G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 811.4531 12.89 9277 5530 2 811.455107 406.7338 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1741.2 - 98963.3 - - - 2.4943 - 1.081 0.141 - 73 1 2 0 0.002 7 0 0 0 1.20E+08 9.32E+06 - - - 0.3286 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.05534.05534.2 0.00467 14-Aug K.EHC[160.03]LVGVK.G sp|Q86U44|MTA70_HUMAN 1 940.48 62.95 9278 5534 2 940.484098 471.2473 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 1741.8 - 813095 - - - 4.318 - 1.535 0.285 - 311.8 1 2 0 0.0041 8 0 0 0 6.65E+07 1.06E+06 - - - 2.4372 0.9938 230117_WJC_METTL3_WT_vs_EV_F02.05789.05789.2 0.0495 14-Jun K.LLEGEESR.L "sp|P08670|VIME_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P17661|DESM_HUMAN,sp|P05787|K2C8_HUMAN,sp|P41219|PERI_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 11 931.4611 1.72 9282 5789 2 931.462285 466.7378 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 1788.3 - 179012 - - - 1.299 - 1.125 0.192 - 117.7 1 2 0 0.0012 8 0 0 0 7.21E+06 4.20E+06 - - - 0.814 0.9944 230117_WJC_METTL3_WT_vs_EV_F02.05913.05913.2 0.163 12-May K.LAEPYGK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 776.4069 1.25 9285 5913 2 776.407443 389.2107 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1810.7 - 298334 - - - 0.7573 - 1.242 0.184 - 98.1 2 2 0 0.0006 7 0 0 0 1.54E+07 1.23E+07 - - - 0.9521 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.06250.06250.2 0.000876 16-Oct R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 2.15 9295 6250 2 969.513336 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1871 - 330292 - - - 1.5028 - 2.019 0.421 - 302.4 1 2 0 0.0015 9 0 0 0 7.69E+07 3.57E+07 - - - 4.1827 0.854 230117_WJC_METTL3_WT_vs_EV_F02.06667.06667.2 3.9 14-May K.VISELNGK[136.11].N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 866.4953 1.18 9311 6667 2 866.497312 434.2549 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1945.8 - 263075 - - - 2.3416 - 0.933 0 - 74.2 1 2 0 0.002 8 0 0 0 1.70E+07 1.44E+07 - - - -1.1688 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.06686.06686.2 0.0129 14-Jul K.VISELNGK.N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 858.4811 1.18 9312 6686 2 858.482971 430.2478 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1949.2 - 364545 - - - 2.1992 - 1.242 0.361 - 165.2 1 2 0 0.0019 8 0 0 0 1.70E+07 1.44E+07 - - - 2.3604 0.998 230117_WJC_METTL3_WT_vs_EV_F02.06962.06962.2 0.152 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 593.21 9322 6962 2 776.382693 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1997.3 - 1.52E+06 - - - 1.2751 - 1.408 0.215 - 183.1 1 2 0 0.001 7 0 0 0 4.99E+09 8.42E+06 - - - 1.7129 0.9932 230117_WJC_METTL3_WT_vs_EV_F02.06964.06964.2 3.06 14-Jul R.GTLDPVEK.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 857.4494 13.43 9323 6964 2 857.450306 429.732 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.37 1997.6 - 368978 - - - 1.0006 - 1.248 0.143 - 132.4 1 2 0 0.0009 8 0 0 0 8.86E+07 6.60E+06 - - - 0.7651 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.07091.07091.2 0.0183 16-Aug K.SAAMTLNER[166.11].F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1001.484 0.82 9330 7091 2 1001.484528 501.7493 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 2019.6 - 674086 - - - 0.5771 - 1.557 0.367 - 130.2 1 2 0 0.0006 9 0 0 0 1.69E+07 2.05E+07 - - - 3.0324 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.07105.07105.2 0.00585 16-Jul K.SAAMTLNER.F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 991.4757 0.82 9331 7105 2 991.474555 496.7451 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 2021.9 - 323638 - - - -1.1347 - 1.682 0.419 - 201.2 1 2 0 -0.0011 9 0 0 0 1.69E+07 2.05E+07 - - - 3.6397 0.9965 230117_WJC_METTL3_WT_vs_EV_F02.07161.07161.2 0.341 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 1.17 9334 7161 2 776.383862 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2031.7 - 582998 - - - 2.7808 - 1.274 0.25 - 175.9 1 2 0 0.0022 7 0 0 0 9.78E+07 8.38E+07 - - - 1.6541 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.07200.07200.2 0.00439 14-Jul K.GANPVEIR.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 854.461 1.87 9337 7200 2 854.461772 428.2378 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 2038.6 - 422897 - - - 0.8848 - 1.409 0.279 - 175.5 1 2 0 0.0008 8 0 0 0 5.83E+07 3.11E+07 - - - 2.1356 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.07267.07267.2 0.0314 14-Sep K.VGEVIVTK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.5208 2.07 9340 7267 2 851.522812 426.7677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2050.6 - 420347 - - - 2.3992 - 2.011 0.335 - 212.6 1 2 0 0.002 8 0 0 0 1.13E+08 5.45E+07 - - - 3.6217 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.07287.07287.2 0.0117 14-Oct K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 2.07 9344 7287 2 843.508391 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2053.9 - 1.78E+06 - - - 2.16 - 2.155 0.341 - 300.5 1 2 0 0.0018 8 0 0 0 1.13E+08 5.45E+07 - - - 3.8747 0.943 230117_WJC_METTL3_WT_vs_EV_F02.07408.07408.2 4.09 12-May R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 188.66 9352 7408 2 776.381065 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2075.2 - 198760 - - - -0.8218 - 1.084 0.096 - 91 2 2 0 -0.0006 7 0 0 0 2.70E+07 1.43E+05 - - - -0.129 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.07602.07602.3 0.0163 Aug-44 R.TLVAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1299.763 0.37 9361 7602 3 1299.764181 434.2616 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2108.8 - 142604 - - - 0.9432 - 1.479 0.336 - 66.1 1 2 0 0.0012 12 0 0 0 2.96E+06 7.90E+06 - - - 3.3705 0.9935 230117_WJC_METTL3_WT_vs_EV_F02.07615.07615.2 2.14 16-Jun K.VTMQNLNDR.L "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 8 1089.5237 999 9363 7615 2 1089.525033 545.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.81 2110.9 - 133883 - - - 1.2308 - 1.185 0.169 - 109.9 1 2 0 0.0013 9 0 0 0 6.71E+06 0.00E+00 - - - 0.7799 0.9241 230117_WJC_METTL3_WT_vs_EV_F02.07640.07640.2 6.16 12-May K.EVSTYIK.K "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 838.4436 2.37 9366 7640 2 838.445904 420.2291 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.1 2115.1 - 287999 - - - 2.7074 - 0.895 0.096 - 129.3 1 2 0 0.0023 7 0 0 0 1.71E+07 7.22E+06 - - - -0.6021 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.07712.07712.2 0.00426 16-Jul R.VLNTNIDGR.R "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1000.5302 1.56 9372 7712 2 1000.5312 501.2724 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.81 2127.4 - 236395 - - - 1.0414 - 1.624 0.295 - 165.3 1 2 0 0.001 9 0 0 0 2.82E+07 1.81E+07 - - - 2.6224 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.07718.07718.2 0.0185 16-Jul R.VLNTNIDGR[166.11].R "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1010.5384 1.55 9374 7718 2 1010.540447 506.2765 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.81 2128.2 - 250684 - - - 1.9979 - 1.573 0.328 - 140.1 1 2 0 0.002 9 0 0 0 2.81E+07 1.81E+07 - - - 2.7735 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.07741.07741.2 0.174 14-Aug R.VLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 815.4753 0.92 9376 7741 2 815.474363 408.7449 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 2132.1 - 485416 - - - -1.111 - 1.491 0.295 - 271.3 1 2 0 -0.0009 8 0 0 0 2.99E+07 3.25E+07 - - - 2.4243 0.9455 230117_WJC_METTL3_WT_vs_EV_F02.07753.07753.2 4.48 14-May R.LASEGSAR.L "sp|Q9HBI6|CP4FB_HUMAN,sp|Q08477|CP4F3_HUMAN,tr|F8W978|F8W978_HUMAN" 3 789.3981 2.04 9380 7753 2 789.400059 395.7063 Cytochrome P450 4F11 OS=Homo sapiens OX=9606 GN=CYP4F11 PE=1 SV=3 6 2133.7 - 171538 - - - 2.5057 - 0.952 0.089 - 104.9 1 2 0 0.002 8 0 0 0 1.41E+07 6.90E+06 - - - -0.4506 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.07775.07775.2 0.00035 16-Jul K.DVDGAYMTK.V sp|P04264|K2C1_HUMAN 1 998.4379 26.75 9384 7775 2 998.439801 500.2262 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.21 2137.1 - 152620 - - - 1.907 - 1.252 0.523 - 109.3 1 2 0 0.0019 9 0 0 0 7.02E+06 2.62E+05 - - - 3.5535 0.9849 230117_WJC_METTL3_WT_vs_EV_F02.07815.07815.2 0.389 14-Aug R.FSELTAEK.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 923.46 7.16 9389 7815 2 923.463874 462.7373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2143.8 - 1.33E+06 - - - 4.181 - 1.193 0.218 - 120.7 1 2 0 0.0039 8 0 0 0 3.60E+07 5.03E+06 - - - 1.1822 0.9845 230117_WJC_METTL3_WT_vs_EV_F02.07824.07824.2 13.6 12-Jul R.IPPVAVR[166.11].L "sp|Q14839|CHD4_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A0G2JM70|A0A0G2JM70_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|V9GYG6|V9GYG6_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 760.4835 0.001 9390 7824 2 760.483869 381.249 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 2145.4 - 547534 - - - 0.5128 - 1.115 0.12 - 182.8 1 2 0 0.0004 7 0 0 0 0.00E+00 1.56E+08 - - - 0.2721 0.9684 230117_WJC_METTL3_WT_vs_EV_F02.07882.07882.2 9.30E-05 16-Oct Y.PDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 953.5546 999 9392 7882 2 953.55455 477.7846 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2155.6 - 441563 - - - -0.0336 - 1.955 0.456 - 369.1 1 1 0 0 9 0 0 0 3.17E+07 0.00E+00 - - - 4.3485 1 230117_WJC_METTL3_WT_vs_EV_F02.07906.07906.2 0.000348 13/18 R.YPDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 1116.6179 592.58 9395 7906 2 1116.620099 559.3162 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2159.6 - 533746 - - - 1.9604 - 2.173 0.543 - 460.2 1 2 0 0.0022 10 0 0 0 8.23E+07 1.39E+05 - - - 5.2173 0.8803 230117_WJC_METTL3_WT_vs_EV_F02.07912.07912.2 0.111 12-Jun D.VIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 784.4807 7.81 9396 7912 2 784.481486 393.2476 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 2160.6 - 1.34E+06 - - - 1.016 - 1.273 0.281 - 156.2 1 1 0 0.0008 7 0 0 0 6.88E+07 8.81E+06 - - - 1.881 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.07981.07981.2 0.000371 16-Oct R.TLLEGEESR.M sp|P04264|K2C1_HUMAN 1 1032.5088 49.94 9405 7981 2 1032.509824 517.2617 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.25 2172.2 - 458599 - - - 1.0363 - 1.749 0.418 - 369.1 1 2 0 0.0011 9 0 0 0 4.02E+07 8.04E+05 - - - 3.7454 0.9493 230117_WJC_METTL3_WT_vs_EV_F02.08002.08002.2 17.5 12-May R.IPPVAVR[166.11].L "sp|Q14839|CHD4_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A0G2JM70|A0A0G2JM70_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|V9GYG6|V9GYG6_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 760.4835 0.001 9408 8002 2 760.483501 381.249 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 2175.6 - 318367 - - - 0.0289 - 1.088 0.072 - 94.1 3 2 0 0 7 0 0 0 0.00E+00 1.56E+08 - - - -0.3731 0.9613 230117_WJC_METTL3_WT_vs_EV_F02.08154.08154.2 0.417 12-May R.FC[160.03]ALEEK.C "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 895.411 0.31 9427 8154 2 895.409752 448.7128 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2200.9 - 190912 - - - -1.3424 - 0.938 0.206 - 74 1 2 0 -0.0012 7 0 0 0 8.35E+06 2.72E+07 - - - 0.3593 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.08225.08225.2 0.132 14-Jul K.C[160.03]GEALGLK.Q "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 846.4269 0.49 9434 8225 2 846.428844 424.2207 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.99 2213.4 - 149941 - - - 2.2506 - 1.608 0.277 - 174.5 1 2 0 0.0019 8 0 0 0 1.63E+07 3.35E+07 - - - 2.5189 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.08233.08233.2 0.0876 12-Sep K.VLAAVYK[136.11].A "sp|P05062|ALDOB_HUMAN,sp|P04075|ALDOA_HUMAN,sp|P09972|ALDOC_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|A8MVZ9|A8MVZ9_HUMAN,tr|A0A3B3IS80|A0A3B3IS80_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|A0A087WXX2|A0A087WXX2_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 10 770.4782 1.93 9435 8233 2 770.479325 386.2464 Fructose-bisphosphate aldolase B OS=Homo sapiens OX=9606 GN=ALDOB PE=1 SV=2 8.56 2214.7 - 692156 - - - 1.4913 - 1.658 0.185 - 330 1 2 0 0.0011 7 0 0 0 1.86E+08 9.61E+07 - - - 2.0091 0.9111 230117_WJC_METTL3_WT_vs_EV_F02.08241.08241.2 0.308 16-Aug R.PSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 969.5243 0.75 9437 8241 2 969.525538 485.7694 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.43 2216 - 181229 - - - 1.2315 - 1.77 0.201 - 201.6 1 1 0 0.0012 9 0 0 0 9.25E+06 1.24E+07 - - - 2.1771 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.08272.08272.2 0.0493 12-Jun R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 244.05 9441 8272 2 808.433126 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2221.1 - 1.14E+06 - - - 0.0693 - 1.386 0.255 - 67.6 1 2 0 0.0001 7 0 0 0 1.26E+08 5.18E+05 - - - 1.9587 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.08279.08279.2 0.00247 18-Nov K.LLNTVEETTK[136.11].D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1154.6274 0.15 9443 8279 2 1154.628874 578.321 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2222.1 - 488950 - - - 1.2601 - 2.304 0.38 - 337.3 1 2 0 0.0015 10 0 0 0 3.41E+06 2.34E+07 - - - 4.177 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.08286.08286.2 0.0193 18-Sep K.LLNTVEETTK.D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1146.6132 0.15 9445 8286 2 1146.616651 574.3139 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2223.1 - 490783 - - - 2.9932 - 1.533 0.297 - 212 1 2 0 0.0034 10 0 0 0 3.41E+06 2.34E+07 - - - 2.4261 0.9949 230117_WJC_METTL3_WT_vs_EV_F02.08298.08298.2 0.156 16-May R.VPPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 942.5651 1.1 9447 8298 2 942.56591 472.2898 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2225 - 157189 - - - 0.8731 - 1.19 0.233 - 55.7 4 2 0 0.0008 9 0 0 0 2.91E+07 2.65E+07 - - - 0.996 0.9878 230117_WJC_METTL3_WT_vs_EV_F02.08301.08301.2 0.781 12-Jul K.LVTDLTK.V "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 788.4644 3.66 9448 8301 2 788.465057 395.2395 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.84 2225.5 - 711439 - - - 0.8713 - 1.316 0.062 - 148.5 1 2 0 0.0007 7 0 0 0 2.77E+07 7.55E+06 - - - 0.3688 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.08302.08302.2 0.322 14-Jul R.ILSGVVTK.M "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 815.5117 0.86 9449 8302 2 815.512262 408.7631 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 2225.6 - 527052 - - - 0.7455 - 1.544 0.16 - 121 1 2 0 0.0006 8 0 0 0 3.58E+07 4.19E+07 - - - 1.5326 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.08400.08400.2 0.156 18-Aug R.ASAVSELSPR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1025.5381 0.82 9462 8400 2 1025.53909 513.7763 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2241.7 - 132585 - - - 0.9712 - 1.655 0.224 - 164.3 1 2 0 0.001 10 0 0 0 1.08E+07 1.32E+07 - - - 2.1014 0.9282 230117_WJC_METTL3_WT_vs_EV_F02.08425.08425.2 1.1 12-Jun R.LLPAEVK[136.11].A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 776.4887 1.26 9465 8425 2 776.487624 389.2516 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6 2245.9 - 2.13E+06 - - - -1.4385 - 1.161 0.116 - 90.3 8 2 0 -0.0011 7 0 0 0 2.42E+08 1.92E+08 - - - -0.033 0.9851 230117_WJC_METTL3_WT_vs_EV_F02.08485.08485.2 4.5 12-May K.SEITELR.R "sp|P13645|K1C10_HUMAN,sp|Q8TDM6|DLG5_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 3 846.4447 3.96 9470 8485 2 846.445041 424.2296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2256 - 260170 - - - 0.4064 - 1.068 0.146 - 133.3 1 2 0 0.0003 7 0 0 0 1.08E+07 2.74E+06 - - - 0.3277 1 230117_WJC_METTL3_WT_vs_EV_F02.08489.08489.2 5.35E-06 13/20 K.FAEALGSTEAK[136.11].A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1130.5699 0.35 9471 8489 2 1130.570665 566.2922 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2256.6 - 331004 - - - 0.6731 - 2.447 0.548 - 528.4 1 2 0 0.0008 11 0 0 0 4.96E+06 1.43E+07 - - - 5.5091 0.9678 230117_WJC_METTL3_WT_vs_EV_F02.08636.08636.2 1.19 16-May R.ILQDSLGGR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 957.5243 0.36 9495 8636 2 957.525723 479.7694 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2280.2 - 143175 - - - 1.4402 - 0.86 0.147 - 61.1 1 2 0 0.0014 9 0 0 0 6.42E+06 1.80E+07 - - - -0.31 0.9554 230117_WJC_METTL3_WT_vs_EV_F02.08728.08728.2 0.895 12-Jul R.LLEQGIR.V "sp|P28340|DPOD1_HUMAN,sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 7 827.4865 1.7 9507 8728 2 827.486127 414.7505 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 6 2295.4 - 315889 - - - -0.4532 - 1.289 0.006 - 148.8 1 2 0 -0.0004 7 0 0 0 3.82E+07 2.24E+07 - - - -0.1104 0.9947 230117_WJC_METTL3_WT_vs_EV_F02.08792.08792.2 0.0747 12-Aug K.NIQVVVR[166.11].C "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 836.5108 0.32 9518 8792 2 836.508971 419.2627 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 9.75 2305.4 - 1.60E+06 - - - -2.1351 - 1.458 0.299 - 280.2 1 2 0 -0.0018 7 0 0 0 2.58E+07 8.08E+07 - - - 2.4436 0.9864 230117_WJC_METTL3_WT_vs_EV_F02.08858.08858.2 0.0773 12-Jun R.AMIIAER[166.11].Q "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 812.4454 1.97 9525 8858 2 812.443165 407.23 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.05 2316.2 - 589908 - - - -2.7251 - 1.413 0.235 - 197.6 1 2 0 -0.0022 7 0 0 0 6.38E+07 3.24E+07 - - - 1.8714 0.998 230117_WJC_METTL3_WT_vs_EV_F02.08929.08929.2 0.291 12-Sep R.HLQLAIR.N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 849.5185 0.82 9537 8929 2 849.519027 425.7665 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2327.4 - 254914 - - - 0.6545 - 1.578 0.179 - 340.7 1 2 0 0.0006 7 0 0 0 9.32E+07 1.14E+08 - - - 1.8083 0.9677 230117_WJC_METTL3_WT_vs_EV_F02.08931.08931.2 14.1 12-Aug R.HLQLAIR[166.11].N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 859.5267 0.82 9538 8931 2 859.527713 430.7706 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2327.7 - 466994 - - - 1.1309 - 1.225 0.001 - 268.1 1 2 0 0.001 7 0 0 0 9.31E+07 1.14E+08 - - - -0.3089 0.9503 230117_WJC_METTL3_WT_vs_EV_F02.08938.08938.2 3.56 12-Jun K.LIETVVK[136.11].Q "sp|Q8TAG9|EXOC6_HUMAN,tr|E7EW84|E7EW84_HUMAN" 2 808.515 1.65 9539 8938 2 808.515983 405.2648 Exocyst complex component 6 OS=Homo sapiens OX=9606 GN=EXOC6 PE=1 SV=3 6 2328.8 - 219064 - - - 1.2715 - 0.887 0.101 - 75.3 1 2 0 0.001 7 0 0 0 1.51E+07 9.16E+06 - - - -0.5933 0.9928 230117_WJC_METTL3_WT_vs_EV_F02.08941.08941.2 0.284 14-Jun K.LVIEEAER.S sp|P50991|TCPD_HUMAN 1 957.5131 16.79 9540 8941 2 957.513087 479.7638 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.25 2329.2 - 140107 - - - -0.0251 - 1.105 0.225 - 118.4 1 2 0 0 8 0 0 0 9.42E+06 5.61E+05 - - - 1.004 0.9865 230117_WJC_METTL3_WT_vs_EV_F02.08975.08975.2 0.239 12-Aug K.IIDAALR.A "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 770.465 2.27 9542 8975 2 770.464309 386.2398 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2335.1 - 1.95E+06 - - - -0.9462 - 1.317 0.14 - 204.4 1 2 0 -0.0007 7 0 0 0 2.40E+09 1.06E+09 - - - 0.9473 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.09056.09056.2 0.392 12-Jul R.VLVDVER[166.11].G sp|P08621|RU17_HUMAN 1 838.4788 1.75 9553 9056 2 838.478907 420.2467 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 4.37 2348.2 - 469783 - - - 0.1419 - 1.511 0.163 - 184.7 1 2 0 0.0001 7 0 0 0 3.38E+07 1.94E+07 - - - 1.5528 0.9942 230117_WJC_METTL3_WT_vs_EV_F02.09152.09152.2 0.732 12-Jul R.LVGEIVR.R "sp|Q13232|NDK3_HUMAN,sp|Q15021|CND1_HUMAN,sp|Q3MIP1|IPIL2_HUMAN,tr|H3BRA8|H3BRA8_HUMAN,tr|H3BMQ7|H3BMQ7_HUMAN,tr|H3BPD9|H3BPD9_HUMAN,tr|E7EN77|E7EN77_HUMAN" 7 784.4807 1.09 9567 9152 2 784.481708 393.2476 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6 2363.4 - 1.62E+06 - - - 1.2989 - 1.345 0.12 - 183.7 1 2 0 0.001 7 0 0 0 4.19E+08 3.83E+08 - - - 0.8661 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.09160.09160.2 3.59 12-Jul R.LVGEIVR[166.11].R "sp|Q13232|NDK3_HUMAN,sp|Q15021|CND1_HUMAN,sp|Q3MIP1|IPIL2_HUMAN,tr|H3BRA8|H3BRA8_HUMAN,tr|H3BMQ7|H3BMQ7_HUMAN,tr|H3BPD9|H3BPD9_HUMAN,tr|E7EN77|E7EN77_HUMAN" 7 794.489 1.59 9569 9160 2 794.4904 398.2518 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6 2364.6 - 3.37E+06 - - - 1.8137 - 1.545 0.16 - 151.8 1 2 0 0.0014 7 0 0 0 6.25E+08 3.94E+08 - - - 1.6007 0.9212 230117_WJC_METTL3_WT_vs_EV_F02.09215.09215.2 0.0439 12-Jul R.PVIVAYK.K "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 788.4796 0.42 9580 9215 2 788.48115 395.2471 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 9.01 2373.5 - 744549 - - - 1.9328 - 1.446 0.296 - 157.5 1 1 0 0.0015 7 0 0 0 2.99E+07 7.11E+07 - - - 2.3953 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.09239.09239.2 0.0144 12-Aug R.FANYIDK.V "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 869.4283 1.65 9582 9239 2 869.428235 435.7214 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.83 2377.5 - 1.13E+06 - - - -0.0966 - 1.652 0.431 - 187.5 1 2 0 -0.0001 7 0 0 0 4.61E+07 2.80E+07 - - - 3.8149 0.9712 230117_WJC_METTL3_WT_vs_EV_F02.09269.09269.2 3.45 14-Jun R.GLDVEDVK.F "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 6 873.4444 0.94 9584 9269 2 873.443586 437.7295 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 2382.6 - 208345 - - - -0.8896 - 1.114 0.136 - 95.8 1 2 0 -0.0008 8 0 0 0 1.21E+07 1.28E+07 - - - 0.3708 0.8953 230117_WJC_METTL3_WT_vs_EV_F02.09276.09276.2 0.0378 14-Aug R.PVGVVVPR[166.11].G "sp|O75525|KHDR3_HUMAN,tr|H0YAQ3|H0YAQ3_HUMAN,tr|E5RJZ9|E5RJZ9_HUMAN,tr|H0YAQ1|H0YAQ1_HUMAN" 4 831.5206 1.15 9587 9276 2 831.520656 416.7676 "KH domain-containing, RNA-binding, signal transduction-associated protein 3 OS=Homo sapiens OX=9606 GN=KHDRBS3 PE=1 SV=1" 10.18 2383.6 - 425150 - - - 0.0758 - 1.37 0.319 - 230.5 1 1 0 0.0001 8 0 0 0 3.05E+07 2.64E+07 - - - 2.3466 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.09306.09306.2 0.00713 16-Aug R.QTVAVGVIK.N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 913.5597 4.27 9591 9306 2 913.560725 457.7871 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2388.5 - 1.18E+06 - - - 1.1581 - 1.739 0.404 - 289.9 1 2 0 0.0011 9 0 0 0 6.63E+07 1.55E+07 - - - 3.6254 0.9597 230117_WJC_METTL3_WT_vs_EV_F02.09321.09321.2 1.85 14-Jun K.VIPELNGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 868.5018 2.7 9593 9321 2 868.503189 435.2582 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2391 - 1.71E+06 - - - 1.5786 - 0.866 0.128 - 95 1 2 0 0.0014 8 0 0 0 8.98E+07 3.32E+07 - - - -0.4479 0.9953 230117_WJC_METTL3_WT_vs_EV_F02.09340.09340.2 0.255 14-May R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 1.14 9600 9340 2 898.525802 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 2393.7 - 236252 - - - 2.4329 - 1.058 0.276 - 84.8 1 2 0 0.0022 8 0 0 0 5.77E+07 5.07E+07 - - - 1.2489 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.09377.09377.2 0.155 12-Jun K.VVPLYGR.G "sp|Q99942|RNF5_HUMAN,tr|A0A140TA09|A0A140TA09_HUMAN" 2 802.4701 2.6 9607 9377 2 802.471976 402.2423 E3 ubiquitin-protein ligase RNF5 OS=Homo sapiens OX=9606 GN=RNF5 PE=1 SV=1 8.72 2399.6 - 1.10E+06 - - - 2.3079 - 1.135 0.279 - 221 1 2 0 0.0019 7 0 0 0 9.12E+07 3.50E+07 - - - 1.5024 0.9349 230117_WJC_METTL3_WT_vs_EV_F02.09434.09434.2 0.00625 14-Jul R.YPDGIISK.P sp|Q86U44|MTA70_HUMAN 1 891.4702 219.87 9619 9434 2 891.472096 446.7424 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2408.9 - 1.62E+06 - - - 2.1459 - 1.313 0.385 - 144.7 1 1 0 0.0019 8 0 0 0 3.81E+08 1.73E+06 - - - 2.7053 0.9884 230117_WJC_METTL3_WT_vs_EV_F02.09445.09445.2 2.93 12-Jun R.IAPDVLR[166.11].K "sp|Q13367|AP3B2_HUMAN,sp|O00203|AP3B1_HUMAN,tr|A0A590UK64|A0A590UK64_HUMAN,tr|A0A590UK04|A0A590UK04_HUMAN,tr|A0A5F9UJV3|A0A5F9UJV3_HUMAN,tr|A0A590UJU0|A0A590UJU0_HUMAN,tr|A0A590UKD3|A0A590UKD3_HUMAN,tr|A0A590UJE5|A0A590UJE5_HUMAN,tr|A0A590UJU7|A0A590UJU7_HUMAN,tr|A0A2R8Y2A8|A0A2R8Y2A8_HUMAN,tr|A0A590UJ60|A0A590UJ60_HUMAN,tr|A0A590UKC4|A0A590UKC4_HUMAN" 12 792.4733 1.57 9622 9445 2 792.475074 397.2439 AP-3 complex subunit beta-2 OS=Homo sapiens OX=9606 GN=AP3B2 PE=1 SV=2 5.84 2410.6 - 903811 - - - 2.2285 - 1.108 0.154 - 119.7 1 2 0 0.0018 7 0 0 0 2.30E+07 1.46E+07 - - - 0.5028 0.9885 230117_WJC_METTL3_WT_vs_EV_F02.09461.09461.2 2.73 16-Jul K.TIAPALVSK.K "sp|P06733|ENOA_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y6I8|A0A2R8Y6I8_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 6 898.5488 0.39 9628 9461 2 898.549888 450.2817 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 8.41 2412.8 - 219573 - - - 1.2465 - 1.133 0.132 - 112.7 1 2 0 0.0011 9 0 0 0 9.25E+06 2.36E+07 - - - 0.3769 0.9556 230117_WJC_METTL3_WT_vs_EV_F02.09474.09474.2 0.13 12-May R.IVTTYIR.E "sp|P50570|DYN2_HUMAN,tr|K7EMQ3|K7EMQ3_HUMAN" 2 864.5069 1.55 9631 9474 2 864.505993 433.2607 Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2 8.75 2414.7 - 174064 - - - -1.0526 - 1.079 0.116 - 79.3 1 2 0 -0.0009 7 0 0 0 2.55E+07 1.64E+07 - - - 0.1384 0.9555 230117_WJC_METTL3_WT_vs_EV_F02.09497.09497.2 1.77 12-May R.IVTTYIR[166.11].E "sp|P50570|DYN2_HUMAN,tr|K7EMQ3|K7EMQ3_HUMAN" 2 874.5152 1.55 9633 9497 2 874.515127 438.2649 Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2 8.75 2418.6 - 431384 - - - -0.0526 - 1.105 0.052 - 71.5 1 2 0 0 7 0 0 0 2.55E+07 1.64E+07 - - - -0.2586 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.09532.09532.2 0.193 14-Aug R.LVTTGVLK.Q sp|P07305|H10_HUMAN 1 829.5273 1.07 9640 9532 2 829.528168 415.7709 Histone H1.0 OS=Homo sapiens OX=9606 GN=H1-0 PE=1 SV=3 8.75 2423.9 - 586011 - - - 1.0416 - 1.805 0.2 - 239.1 1 2 0 0.0009 8 0 0 0 2.74E+07 2.57E+07 - - - 2.299 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.09538.09538.2 0.0221 18-Jun R.GYSFTTTAER[166.11].E "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1141.5279 1.34 9643 9538 2 1141.527946 571.7712 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 2424.7 - 90731.6 - - - 0.0201 - 1.259 0.348 - 94 1 2 0 0 10 0 0 0 6.06E+06 4.53E+06 - - - 2.2542 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.09540.09540.2 0.00293 18-Aug R.GYSFTTTAER.E "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1131.5197 1.32 9644 9540 2 1131.520746 566.7671 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 2424.9 - 146125 - - - 0.966 - 1.489 0.395 - 256 1 2 0 0.0011 10 0 0 0 6.06E+06 4.58E+06 - - - 3.0694 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.09551.09551.2 0.0219 18-Sep K.FADLSEAANR.N "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1092.52 1.47 9646 9551 2 1092.52145 547.2673 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 2426.7 - 183418 - - - 1.3391 - 1.783 0.357 - 280.4 1 2 0 0.0015 10 0 0 0 2.60E+07 1.77E+07 - - - 3.2915 0.9872 230117_WJC_METTL3_WT_vs_EV_F02.09605.09605.2 0.103 16-May R.QAVDVSPLR[166.11].R "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 993.5483 0.79 9657 9605 2 993.550309 497.7814 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 5.84 2435 - 99450 - - - 2.0583 - 1.107 0.161 - 63.4 2 2 0 0.002 9 0 0 0 3.65E+06 4.63E+06 - - - 0.3891 0.9937 230117_WJC_METTL3_WT_vs_EV_F02.09636.09636.2 4.71 14-May R.LLTGPVVR.G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 853.5385 2.53 9665 9636 2 853.539442 427.7765 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2439.7 - 380985 - - - 1.0591 - 1.24 0.152 - 68.5 1 2 0 0.0009 8 0 0 0 3.92E+07 1.55E+07 - - - 0.8122 0.9886 230117_WJC_METTL3_WT_vs_EV_F02.09656.09656.2 0.595 12-Jun K.LEPVPLK.G "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN" 2 794.4902 2.54 9671 9656 2 794.49057 398.2524 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6 2442.7 - 1.26E+06 - - - 0.477 - 1.158 0.134 - 167.6 1 2 0 0.0004 7 0 0 0 6.22E+07 2.45E+07 - - - 0.4954 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.09662.09662.2 0.0281 14-Jul K.ALVAYYQK[136.11].Y "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 962.5317 3.13 9673 9662 2 962.533123 482.2731 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.54 2443.5 - 265695 - - - 1.5116 - 1.485 0.255 - 142.6 1 2 0 0.0015 8 0 0 0 2.67E+07 8.53E+06 - - - 2.1165 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.09722.09722.2 0.0631 12-Jul R.LGPETFR[166.11].Q sp|P57086|SCND1_HUMAN 1 828.4369 1.8 9686 9722 2 828.438214 415.2257 SCAN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCAND1 PE=1 SV=1 6 2452.7 - 242368 - - - 1.5584 - 1.257 0.229 - 134 1 2 0 0.0013 7 0 0 0 3.59E+07 2.00E+07 - - - 1.4567 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.09725.09725.3 0.00511 Dec-40 R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 1.16 9687 9725 3 1240.608697 414.5431 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2453.1 - 211227 - - - 0.9084 - 1.551 0.326 - 126.3 1 2 0 0.0011 11 0 0 0 2.64E+07 2.27E+07 - - - 3.4211 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.09738.09738.2 0.0329 16-Jul K.IVVVTAGVR[166.11].Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 922.5839 0.82 9690 9738 2 922.584635 462.2992 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2455.1 - 512554 - - - 0.7728 - 1.521 0.246 - 122.5 1 2 0 0.0007 9 0 0 0 1.54E+08 1.88E+08 - - - 2.071 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.09752.09752.2 0.0162 16-Aug K.IVVVTAGVR.Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 912.5757 0.8 9692 9752 2 912.576116 457.2951 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2457.4 - 1.36E+06 - - - 0.5085 - 1.747 0.307 - 265.4 1 2 0 0.0005 9 0 0 0 1.51E+08 1.88E+08 - - - 2.9224 0.9573 230117_WJC_METTL3_WT_vs_EV_F02.09768.09768.2 1.67 12-Jun K.LEATMLR[166.11].L "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 842.4559 3.98 9696 9768 2 842.455111 422.2352 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6 2459.8 - 265709 - - - -0.9888 - 1.198 0.071 - 83.9 1 2 0 -0.0008 7 0 0 0 1.02E+08 2.56E+07 - - - 0.1376 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.09780.09780.2 0.0252 22-Jul R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 137.89 9698 9780 2 1380.643831 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2461.8 - 101518 - - - 2.1302 - 1.414 0.29 - 118.6 1 2 0 0.0029 12 0 0 0 6.62E+06 4.80E+04 - - - 2.0935 0.9784 230117_WJC_METTL3_WT_vs_EV_F02.09786.09786.2 2.5 14-Jun R.ILADEALK.L sp|Q08426|ECHP_HUMAN 1 871.5015 1.22 9701 9786 2 871.50215 436.758 Peroxisomal bifunctional enzyme OS=Homo sapiens OX=9606 GN=EHHADH PE=1 SV=3 4.37 2462.5 - 391838 - - - 0.7642 - 1.081 0.116 - 48.9 2 2 0 0.0007 8 0 0 0 8.66E+06 7.13E+06 - - - -0.002 0.9877 230117_WJC_METTL3_WT_vs_EV_F02.09799.09799.2 1.59 12-Jun K.ILLSPER.V "sp|P24928|RPB1_HUMAN,tr|H3BVE3|H3BVE3_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 3 826.4913 0.98 9706 9799 2 826.493976 414.2529 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 6 2464.2 - 349002 - - - 3.2947 - 1.329 0.128 - 120.3 1 2 0 0.0027 7 0 0 0 9.54E+07 9.72E+07 - - - 0.8868 0.8483 230117_WJC_METTL3_WT_vs_EV_F02.09808.09808.2 1.35 12-Aug N.LNTLIQR.S "sp|P20036|DPA1_HUMAN,sp|Q00839|HNRPU_HUMAN,sp|Q8IUG5|MY18B_HUMAN,tr|A0A140T914|A0A140T914_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|F5H6I8|F5H6I8_HUMAN,tr|A0A140T9R4|A0A140T9R4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A140T9D6|A0A140T9D6_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A140T9Y9|A0A140T9Y9_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A140T9H1|A0A140T9H1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A140T9U4|A0A140T9U4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A140T9F8|A0A140T9F8_HUMAN,tr|J3KQ99|J3KQ99_HUMAN" 24 856.5131 0.26 9709 9808 2 856.513879 429.2638 "HLA class II histocompatibility antigen, DP alpha 1 chain OS=Homo sapiens OX=9606 GN=HLA-DPA1 PE=1 SV=1" 9.75 2465.4 - 2.45E+06 - - - 0.9667 - 1.641 0.14 - 284.2 1 1 0 0.0008 7 0 0 0 9.08E+07 3.54E+08 - - - 1.6442 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.09813.09813.2 0.0181 18-Nov K.IGAVEEELNR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1138.5858 0.76 9712 9813 2 1138.589971 570.3002 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.25 2466.1 - 134664 - - - 3.6879 - 2.01 0.354 - 403.4 1 2 0 0.0042 10 0 0 0 5.54E+06 7.26E+06 - - - 3.603 0.8829 230117_WJC_METTL3_WT_vs_EV_F02.09829.09829.2 0.206 12-Jun N.VDEFVK[136.11]R.L sp|Q9NVH2|INT7_HUMAN 1 899.4956 - 9716 9829 2 899.496932 450.7551 Integrator complex subunit 7 OS=Homo sapiens OX=9606 GN=INTS7 PE=1 SV=1 6.04 2468.6 - 501054 - - - 1.4619 - 1.367 0.251 - 110 1 1 0 0.0013 7 0 0 0 - - - - - 1.885 0.999 230117_WJC_METTL3_WT_vs_EV_F02.09857.09857.2 0.0213 18-Jul K.MLVSGAGDIK.L "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 989.5216 29.9 9720 9857 2 989.522164 495.7681 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.59 2473.1 - 303737 - - - 0.6033 - 1.491 0.315 - 87.5 1 2 0 0.0006 10 0 0 0 1.32E+07 4.41E+05 - - - 2.4824 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.09891.09891.2 0.0843 12-Jul R.MIVGTLK.G "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 760.4517 2.59 9727 9891 2 760.451868 381.2331 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 8.5 2478.5 - 1.60E+06 - - - 0.2249 - 1.306 0.203 - 199.7 1 2 0 0.0002 7 0 0 0 3.64E+08 1.40E+08 - - - 1.3862 0.9936 230117_WJC_METTL3_WT_vs_EV_F02.09908.09908.2 0.693 12-Jul R.ILLEAAR[166.11].L "sp|P49189|AL9A1_HUMAN,sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 3 794.489 2.19 9730 9908 2 794.488755 398.2518 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3 6 2481.2 - 707208 - - - -0.2568 - 1.424 0.139 - 182 1 2 0 -0.0002 7 0 0 0 6.76E+07 3.08E+07 - - - 1.1876 0.9459 230117_WJC_METTL3_WT_vs_EV_F02.09926.09926.2 3.27 12-May R.ILLEAAR.L "sp|P49189|AL9A1_HUMAN,sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 3 784.4807 2.21 9734 9926 2 784.480292 393.2476 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3 6 2483.9 - 1.66E+06 - - - -0.5061 - 1.255 0.054 - 67.8 7 2 0 -0.0004 7 0 0 0 6.87E+07 3.11E+07 - - - -0.2181 0.999 230117_WJC_METTL3_WT_vs_EV_F02.09981.09981.2 0.0321 16-Aug R.SLVNLGGSK.S sp|P04264|K2C1_HUMAN 1 873.492 55.3 9740 9981 2 873.4919 437.7533 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.47 2493 - 389099 - - - -0.0939 - 1.46 0.375 - 220.8 1 2 0 -0.0001 9 0 0 0 4.86E+07 8.78E+05 - - - 2.9056 0.9724 230117_WJC_METTL3_WT_vs_EV_F02.09991.09991.2 8.5 12-Jul K.LGPEAFR[166.11].F sp|P33908|MA1A1_HUMAN 1 798.4264 0.42 9742 9991 2 798.426752 400.2205 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 6 2494.6 - 497274 - - - 0.4935 - 1.178 0.045 - 170 1 2 0 0.0004 7 0 0 0 5.47E+07 1.29E+08 - - - -0.1077 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.09996.09996.2 0.00547 14-Jul R.VMGLVPAK.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 813.4782 1.65 9744 9996 2 813.478148 407.7464 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.72 2495.3 - 141394 - - - -0.1205 - 1.333 0.29 - 133.1 1 2 0 -0.0001 8 0 0 0 4.41E+07 2.68E+07 - - - 2.0498 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.10021.10021.2 0.145 14-Sep R.VMGLVPAK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 821.4924 1.65 9749 10021 2 821.493264 411.7535 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.72 2499.2 - 531221 - - - 0.9957 - 1.432 0.193 - 245.2 1 2 0 0.0008 8 0 0 0 4.41E+07 2.67E+07 - - - 1.5492 1 230117_WJC_METTL3_WT_vs_EV_F02.10040.10040.2 2.54E-07 22-Oct R.AQVQEFC[160.03]DYGTK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1444.6293 6.51 9753 10040 2 1444.630953 723.3219 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2502.1 - 125853 - - - 1.1581 - 1.942 0.682 - 274.8 1 2 0 0.0017 12 0 0 0 2.48E+07 3.82E+06 - - - 5.8241 0.9114 230117_WJC_METTL3_WT_vs_EV_F02.10043.10043.2 2.14 22-Feb R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 6.51 9754 10043 2 1452.64433 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2502.5 - 32601.9 - - - 0.5851 - 0.619 0.198 - 13.6 2 2 0 0.0008 12 0 0 0 2.48E+07 3.82E+06 - - - -0.8934 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.10056.10056.2 0.0385 12-Jul R.LMDVMAK.E sp|Q12874|SF3A3_HUMAN 1 806.403 3.01 9757 10056 2 806.402303 404.2088 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2504.6 - 387861 - - - -0.904 - 1.434 0.321 - 164.6 1 2 0 -0.0007 7 0 0 0 1.24E+08 4.11E+07 - - - 2.5538 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.10067.10067.2 0.0116 12-Jul R.LMDVMAK[136.11].E sp|Q12874|SF3A3_HUMAN 1 814.4172 3.01 9758 10067 2 814.417688 408.2159 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2506.5 - 496850 - - - 0.5599 - 1.422 0.379 - 136.7 1 2 0 0.0005 7 0 0 0 1.24E+08 4.11E+07 - - - 2.9557 0.9496 230117_WJC_METTL3_WT_vs_EV_F02.10099.10099.2 0.379 12-May -.MAAPILR.S sp|Q9Y2Z4|SYYM_HUMAN 1 770.4473 4.03 9762 10099 2 770.447157 386.2309 "Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2" 9.5 2512 - 1.80E+06 - - - -0.1596 - 1.26 0.026 - 116.1 4 2 0 -0.0001 7 0 0 0 1.37E+08 3.39E+07 - - - -0.3037 0.9922 230117_WJC_METTL3_WT_vs_EV_F02.10125.10125.2 0.765 12-Jun K.IFGGEIK.T "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 15 762.4276 1 9767 10125 2 762.428507 382.2211 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 2516.4 - 1.72E+06 - - - 1.2027 - 1.318 0.099 - 91.5 1 2 0 0.0009 7 0 0 0 1.43E+08 1.43E+08 - - - 0.6468 0.9876 230117_WJC_METTL3_WT_vs_EV_F02.10135.10135.2 1.8 14-Jul R.IIAEALTR[166.11].V "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 5 895.5366 0.93 9769 10135 2 895.538048 448.7756 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 2518 - 868489 - - - 1.5756 - 1.258 0.099 - 133 2 2 0 0.0014 8 0 0 0 4.92E+07 5.28E+07 - - - 0.3295 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.10168.10168.2 0.608 16-Aug K.VELQELNDR.F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1114.5619 2.8 9776 10168 2 1114.565918 558.2882 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.14 2523.2 - 157663 - - - 3.6481 - 1.787 0.255 - 294.6 1 2 0 0.0041 9 0 0 0 1.87E+07 6.67E+06 - - - 2.6027 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.10170.10170.2 0.829 12-Aug K.EGIVALR[166.11].R sp|P40227|TCPZ_HUMAN 1 766.4577 0.52 9777 10170 2 766.458416 384.2361 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 6.1 2523.5 - 766913 - - - 0.989 - 1.604 0.154 - 263.7 1 2 0 0.0008 7 0 0 0 4.87E+07 9.44E+07 - - - 1.6754 0.9321 230117_WJC_METTL3_WT_vs_EV_F02.10186.10186.3 0.0538 Apr-64 R.AQVQEFC[160.03]DYGTKEEC[160.03]MK.A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2121.8806 5.9 9780 10186 3 2121.883601 708.3008 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2526.1 - 36001.6 - - - 1.4317 - 1.005 0.418 - 9.7 1 2 1 0.003 17 0 0 0 1.28E+06 2.17E+05 - - - 3.212 0.9794 230117_WJC_METTL3_WT_vs_EV_F02.10204.10204.2 0.0904 12-Jun R.VLYSLAK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 792.4745 1.3 9784 10204 2 792.47289 397.2445 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.56 2528.8 - 511326 - - - -2.0833 - 1.442 0.132 - 125.2 1 2 0 -0.0017 7 0 0 0 6.18E+07 4.77E+07 - - - 1.1752 0.9238 230117_WJC_METTL3_WT_vs_EV_F02.10239.10239.2 9.64 12-Jun R.LYTVVPR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 846.4963 1.71 9789 10239 2 846.49666 424.2554 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 2534.4 - 1.06E+06 - - - 0.3792 - 0.961 0.046 - 138.7 1 2 0 0.0003 7 0 0 0 1.78E+08 1.04E+08 - - - -0.7454 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.10268.10268.2 0.304 14-Aug K.IPAMTIAK.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.4888 2.16 9796 10268 2 843.488714 422.7517 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2538.6 - 8.91E+06 - - - -0.1138 - 1.315 0.29 - 185.5 1 2 0 -0.0001 8 0 0 0 2.06E+09 9.50E+08 - - - 2.0088 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.10270.10270.2 0.0472 12-Jun R.LYTVVPR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 856.5046 1.69 9797 10270 2 856.505142 429.2596 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 2538.9 - 1.93E+06 - - - 0.6223 - 1.287 0.232 - 142.8 1 2 0 0.0005 7 0 0 0 1.78E+08 1.05E+08 - - - 1.5539 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.10283.10283.2 0.00472 16-May R.VLPVYGGPK.G "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 928.5382 1.68 9802 10283 2 928.539264 465.2764 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 8.56 2540.7 - 135923 - - - 1.1427 - 1.215 0.28 - 64.5 1 2 0 0.0011 9 0 0 0 2.03E+07 1.21E+07 - - - 1.6722 0.9943 230117_WJC_METTL3_WT_vs_EV_F02.10333.10333.2 0.45 14-Aug R.LLTGPVVR[166.11].G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 863.5468 2.13 9815 10333 2 863.545507 432.7807 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2548 - 2.76E+06 - - - -1.5066 - 1.555 0.216 - 195.8 1 2 0 -0.0013 8 0 0 0 3.33E+08 1.56E+08 - - - 1.9674 0.9793 230117_WJC_METTL3_WT_vs_EV_F02.10345.10345.2 4.01 14-Jul R.LLTGPVVR.G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 853.5385 2.13 9816 10345 2 853.536289 427.7765 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2549.9 - 6.27E+06 - - - -2.6349 - 1.41 0.186 - 138 1 2 0 -0.0022 8 0 0 0 3.33E+08 1.56E+08 - - - 1.4503 0.995 230117_WJC_METTL3_WT_vs_EV_F02.10388.10388.2 0.091 16-Sep K.LSDGVAVLK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 908.5422 2.47 9820 10388 2 908.540142 455.2784 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2556.9 - 1.26E+06 - - - -2.3015 - 1.777 0.261 - 162.1 1 2 0 -0.0021 9 0 0 0 2.25E+08 9.10E+07 - - - 2.6314 0.9519 230117_WJC_METTL3_WT_vs_EV_F02.10462.10462.2 3.07 12-Jun K.GDVQTIR.W sp|Q702N8|XIRP1_HUMAN 1 787.4188 530.44 9822 10462 2 787.417353 394.7167 Xin actin-binding repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=XIRP1 PE=1 SV=1 5.84 2569.5 - 7.36E+06 - - - -1.8592 - 1.234 0.098 - 215.9 1 2 0 -0.0015 7 0 0 0 3.96E+08 7.47E+05 - - - 0.4306 0.9761 230117_WJC_METTL3_WT_vs_EV_F02.10466.10466.2 5.6 12-Jul R.LLAALER[166.11].R sp|Q96A98|TIP39_HUMAN 1 794.489 1.27 9823 10466 2 794.487905 398.2518 Tuberoinfundibular peptide of 39 residues OS=Homo sapiens OX=9606 GN=PTH2 PE=1 SV=1 6 2570 - 3.09E+06 - - - -1.3266 - 1.592 0.054 - 152.2 3 2 0 -0.0011 7 0 0 0 1.49E+09 1.17E+09 - - - 0.6997 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.10484.10484.2 0.000631 12-Aug R.LVDMMER.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 892.4147 1.14 9827 10484 2 892.41473 447.2146 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 2572.7 - 1.84E+06 - - - 0.0796 - 1.344 0.509 - 241.4 1 2 0 0.0001 7 0 0 0 1.96E+08 1.71E+08 - - - 3.7372 0.9921 230117_WJC_METTL3_WT_vs_EV_F02.10505.10505.2 0.255 12-Jun R.LVDMMER[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 902.4229 1.14 9830 10505 2 902.422194 452.2187 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 2576 - 4.24E+06 - - - -0.8145 - 1.134 0.252 - 121.8 1 2 0 -0.0007 7 0 0 0 1.96E+08 1.71E+08 - - - 1.3005 0.9661 230117_WJC_METTL3_WT_vs_EV_F02.10515.10515.2 0.00431 14-Sep K.PSPLLVGR.E "sp|Q13283|G3BP1_HUMAN,sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2R0|A0A7I2V2R0_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RGJ4|D6RGJ4_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|D6R9A4|D6R9A4_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|E5RI46|E5RI46_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 25 837.5072 0.9 9833 10515 2 837.508689 419.7609 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 10.18 2577.3 - 1.64E+06 - - - 1.7325 - 1.733 0.374 - 328.1 1 1 0 0.0015 8 0 0 0 1.09E+08 1.21E+08 - - - 3.4612 0.9826 230117_WJC_METTL3_WT_vs_EV_F02.10516.10516.2 1.86 14-Aug R.VVLLAEGR.L sp|O43865|SAHH2_HUMAN 1 855.5178 4.15 9834 10516 2 855.515643 428.7662 S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1 PE=1 SV=2 5.97 2577.4 - 1.10E+06 - - - -2.5236 - 1.486 0.177 - 237.3 1 2 0 -0.0022 8 0 0 0 4.37E+07 1.05E+07 - - - 1.5422 0.9954 230117_WJC_METTL3_WT_vs_EV_F02.10534.10534.2 0.0949 12-Jul K.FIGELGK.L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 762.4276 2.26 9836 10534 2 762.426888 382.2211 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2580.3 - 1.23E+06 - - - -0.9207 - 1.492 0.205 - 185.7 1 2 0 -0.0007 7 0 0 0 2.70E+08 1.19E+08 - - - 1.8227 0.9773 230117_WJC_METTL3_WT_vs_EV_F02.10548.10548.2 0.0602 12-Jul K.FIGELGK[136.11].L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 770.4418 2.21 9839 10548 2 770.438473 386.2282 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2582.5 - 2.21E+06 - - - -4.3053 - 1.452 0.284 - 176.5 1 2 0 -0.0033 7 0 0 0 2.63E+08 1.19E+08 - - - 2.3193 0.991 230117_WJC_METTL3_WT_vs_EV_F02.10563.10563.2 0.00836 14-Aug R.LGPLQVAR.V sp|P38117|ETFB_HUMAN 1 852.5181 2.59 9842 10563 2 852.515341 427.2663 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 9.75 2584.7 - 5.07E+06 - - - -3.2797 - 1.671 0.279 - 252.7 1 2 0 -0.0028 8 0 0 0 2.61E+08 1.01E+08 - - - 2.6493 0.9926 230117_WJC_METTL3_WT_vs_EV_F02.10616.10616.2 3.82 12-Jul K.LDIAAVR[166.11].A "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 766.4577 0.09 9856 10616 2 766.45761 384.2361 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 5.84 2592.1 - 764589 - - - -0.0626 - 1.511 0.087 - 161.1 1 2 0 0 7 0 0 0 4.36E+06 5.10E+07 - - - 0.9915 0.9789 230117_WJC_METTL3_WT_vs_EV_F02.10632.10632.2 3.88 12-Jun K.AIFAGYK.R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 768.417 0.81 9857 10632 2 768.417257 385.2158 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2594.8 - 628809 - - - 0.3006 - 1.084 0.112 - 115 1 2 0 0.0002 7 0 0 0 2.38E+08 2.95E+08 - - - 0.1237 0.8774 230117_WJC_METTL3_WT_vs_EV_F02.10638.10638.2 2.64 12-Apr R.LPPDVLR[166.11].W sp|P78527|PRKDC_HUMAN 1 818.489 15.35 9859 10638 2 818.488791 410.2518 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2595.7 - 778496 - - - -0.2053 - 1.031 0.068 - 45.2 15 2 0 -0.0002 7 0 0 0 1.19E+09 7.78E+07 - - - -0.8854 0.9944 230117_WJC_METTL3_WT_vs_EV_F02.10640.10640.2 0.23 12-Jun K.AIFAGYK[136.11].R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 776.4312 0.81 9860 10640 2 776.431493 389.2229 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2595.9 - 2.21E+06 - - - 0.3439 - 1.136 0.219 - 149.2 1 2 0 0.0003 7 0 0 0 2.38E+08 2.95E+08 - - - 1.0625 0.9492 230117_WJC_METTL3_WT_vs_EV_F02.10651.10651.2 0.362 12-Jul R.FLAPYGR.Q "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 822.4388 0.3 9861 10651 2 822.436103 412.2267 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 8.75 2597.7 - 671604 - - - -3.3085 - 1.288 0.163 - 197.5 1 2 0 -0.0027 7 0 0 0 6.80E+07 2.28E+08 - - - 1.046 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.10667.10667.2 0.0395 14-Jun K.YVPLADVK[136.11].S "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 911.5208 0.72 9862 10667 2 911.521067 456.7677 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.83 2600.5 - 618793 - - - 0.3269 - 1.262 0.32 - 128.8 1 2 0 0.0003 8 0 0 0 5.65E+07 7.84E+07 - - - 2.1062 0.9964 230117_WJC_METTL3_WT_vs_EV_F02.10671.10671.2 0.249 16-Aug R.QEYEQLIAK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1120.5764 0.49 9863 10671 2 1120.58192 561.2955 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.53 2601.1 - 256443 - - - 4.8903 - 1.661 0.349 - 235.6 1 2 0 0.0055 9 0 0 0 1.44E+07 2.94E+07 - - - 3.085 0.9904 230117_WJC_METTL3_WT_vs_EV_F02.10678.10678.2 0.369 12-Jun R.VLISSLK.D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 758.4902 0.93 9865 10678 2 758.491415 380.2524 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2602.2 - 316211 - - - 1.6137 - 1.283 0.092 - 95.2 1 2 0 0.0012 7 0 0 0 1.09E+08 1.17E+08 - - - 0.5097 0.9794 230117_WJC_METTL3_WT_vs_EV_F02.10682.10682.2 0.249 12-May K.VLLAEYK.N sp|Q16513|PKN2_HUMAN 1 834.4851 0 9866 10682 2 834.485996 418.2498 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 5.97 2602.7 - 1.03E+06 - - - 1.0677 - 1.144 0.071 - 80.9 1 2 0 0.0009 7 0 0 0 6.32E+07 1.70E+10 - - - -0.0086 0.9875 230117_WJC_METTL3_WT_vs_EV_F02.10684.10684.2 0.923 12-Jun R.LPPDVLR.W sp|P78527|PRKDC_HUMAN 1 808.4807 11.22 9867 10684 2 808.481205 405.2476 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2602.9 - 979579 - - - 0.6382 - 1.145 0.125 - 116.7 1 2 0 0.0005 7 0 0 0 9.24E+08 8.23E+07 - - - 0.3931 0.9917 230117_WJC_METTL3_WT_vs_EV_F02.10699.10699.2 0.768 14-Aug K.LLEATELK[136.11].G "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 923.5419 1.13 9873 10699 2 923.543996 462.7782 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 2604.9 - 863889 - - - 2.2717 - 1.456 0.079 - 158.5 1 2 0 0.0021 8 0 0 0 4.76E+07 4.23E+07 - - - 0.7569 0.9879 230117_WJC_METTL3_WT_vs_EV_F02.10709.10709.2 1.28 12-May K.SVLTPLR[166.11].G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 794.489 1.11 9875 10709 2 794.489781 398.2518 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2606.5 - 866973 - - - 1.0346 - 1.136 0.123 - 90.1 1 2 0 0.0008 7 0 0 0 5.64E+07 5.08E+07 - - - 0.3533 0.9953 230117_WJC_METTL3_WT_vs_EV_F02.10713.10713.2 1.74 12-Jun R.VLISSLK[136.11].D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 766.5044 1.17 9876 10713 2 766.505267 384.2595 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2607 - 1.72E+06 - - - 1.1429 - 1.302 0.156 - 141.4 1 2 0 0.0009 7 0 0 0 1.07E+08 9.20E+07 - - - 1.0291 0.9894 230117_WJC_METTL3_WT_vs_EV_F02.10717.10717.2 1.09 12-Jun K.SVLTPLR.G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 784.4807 1.14 9878 10717 2 784.481094 393.2476 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2607.6 - 1.21E+06 - - - 0.5163 - 1.143 0.145 - 128.2 1 2 0 0.0004 7 0 0 0 5.82E+07 5.09E+07 - - - 0.5353 0.9911 230117_WJC_METTL3_WT_vs_EV_F02.10724.10724.2 0.127 12-May R.LLDVYEK.E "sp|Q96EF6|FBX17_HUMAN,tr|M0R2C6|M0R2C6_HUMAN,tr|M0QZ95|M0QZ95_HUMAN" 3 878.4749 1.94 9882 10724 2 878.47803 440.2447 F-box only protein 17 OS=Homo sapiens OX=9606 GN=FBXO17 PE=1 SV=1 4.37 2608.5 - 189949 - - - 3.5243 - 1.154 0.238 - 56.9 1 2 0 0.0031 7 0 0 0 1.11E+07 5.72E+06 - - - 1.2517 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.10731.10731.2 1.53 14-Aug R.ILLAVNGK.V sp|O15173|PGRC2_HUMAN 1 826.5276 1.66 9884 10731 2 826.529533 414.2711 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.75 2609.4 - 318145 - - - 2.2915 - 1.341 0.248 - 142.5 1 2 0 0.0019 8 0 0 0 4.30E+07 2.60E+07 - - - 1.7571 0.9969 230117_WJC_METTL3_WT_vs_EV_F02.10746.10746.2 1.41 12-Aug R.IVEGILK.R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 770.4902 2.04 9890 10746 2 770.491145 386.2524 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 2611.4 - 1.98E+06 - - - 1.2382 - 1.611 0.109 - 173.9 1 2 0 0.001 7 0 0 0 6.62E+08 3.25E+08 - - - 1.3567 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.10770.10770.2 6.81E-05 26-Aug R.SLYASSPGGVYATR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1427.7045 1.88 9896 10770 2 1427.710229 714.8595 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2615 - 77781 - - - 4.0169 - 1.731 0.468 - 148.3 1 2 0 0.0057 14 0 0 0 6.92E+06 3.67E+06 - - - 3.8728 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.10773.10773.2 0.0357 12-Aug K.MGITPLR.N "sp|Q12789|TF3C1_HUMAN,sp|O43325|LYRM1_HUMAN,tr|H3BNA8|H3BNA8_HUMAN" 3 786.4422 1.18 9897 10773 2 786.443488 394.2284 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 9.5 2615.5 - 603231 - - - 1.6441 - 1.775 0.287 - 215.4 1 2 0 0.0013 7 0 0 0 5.73E+07 4.85E+07 - - - 2.9785 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.10777.10777.2 0.0526 18-Aug R.IITEGFEAAK.E sp|P40227|TCPZ_HUMAN 1 1077.5706 9.64 9900 10777 2 1077.572467 539.7926 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 2616 - 362654 - - - 1.7085 - 1.506 0.333 - 130.6 1 2 0 0.0018 10 0 0 0 3.43E+07 3.56E+06 - - - 2.6429 0.9906 230117_WJC_METTL3_WT_vs_EV_F02.10783.10783.2 1.28 12-Jun R.LLIGEPR.G sp|Q9H0L4|CSTFT_HUMAN 1 796.4807 3.01 9902 10783 2 796.482107 399.2476 Cleavage stimulation factor subunit 2 tau variant OS=Homo sapiens OX=9606 GN=CSTF2T PE=1 SV=1 6 2616.8 - 1.64E+06 - - - 1.7803 - 1.249 0.109 - 112.1 1 2 0 0.0014 7 0 0 0 1.20E+08 3.98E+07 - - - 0.5501 0.9928 230117_WJC_METTL3_WT_vs_EV_F02.10798.10798.2 9.21 14-Jun R.VIQALAMK[136.11].G "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 880.5296 1.21 9909 10798 2 880.531161 441.2721 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.72 2618.8 - 307012 - - - 1.8182 - 1.245 0.141 - 91.9 1 2 0 0.0016 8 0 0 0 2.07E+07 1.71E+07 - - - 0.7428 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.10800.10800.2 0.00688 26-Oct R.SLYASSPGGVYATR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1437.7128 1.88 9910 10800 2 1437.71737 719.8637 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2619 - 119178 - - - 3.2037 - 2.244 0.462 - 189.2 1 2 0 0.0046 14 0 0 0 6.92E+06 3.67E+06 - - - 4.4802 0.8744 230117_WJC_METTL3_WT_vs_EV_F02.10807.10807.2 0.392 16-Jul R.PGPLLVSAR.R sp|Q9NUL7|DDX28_HUMAN 1 908.5444 1.23 9914 10807 2 908.545906 455.2795 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 10.18 2619.9 - 101367 - - - 1.7115 - 1.477 0.226 - 112.1 1 1 0 0.0016 9 0 0 0 7.56E+07 6.14E+07 - - - 1.8381 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.10811.10811.2 0.002 14-Sep R.VIQALAMK.G "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 872.5154 1.21 9915 10811 2 872.516753 437.265 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.72 2620.5 - 462367 - - - 1.5965 - 1.679 0.425 - 224 1 2 0 0.0014 8 0 0 0 2.07E+07 1.71E+07 - - - 3.7425 0.9947 230117_WJC_METTL3_WT_vs_EV_F02.10812.10812.2 0.26 12-Jun R.TFLVGER[166.11].V sp|P26641|EF1G_HUMAN 1 830.4526 0.76 9916 10812 2 830.454524 416.2336 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.66 2620.7 - 404947 - - - 2.3493 - 1.298 0.17 - 138.4 1 2 0 0.002 7 0 0 0 1.27E+07 1.66E+07 - - - 1.1224 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.10813.10813.2 0.193 12-Aug K.LTGMAFR.V "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 794.4109 -1 9917 10813 2 794.412354 398.2127 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 9.75 2620.8 - 841702 - - - 1.8378 - 1.737 0.27 - 192.8 1 2 0 0.0015 7 0 0 0 0.00E+00 0.00E+00 - - - 2.7843 0.9846 230117_WJC_METTL3_WT_vs_EV_F02.10824.10824.2 1.14 16-Jun K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 0.84 9921 10824 2 993.585249 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2622.3 - 170899 - - - 0.6029 - 1.144 0.141 - 90.5 3 2 0 0.0006 9 0 0 0 7.81E+07 9.34E+07 - - - 0.2583 0.989 230117_WJC_METTL3_WT_vs_EV_F02.10831.10831.2 18.1 12-Jul R.LIITQVR.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 841.5385 0.99 9925 10831 2 841.540355 421.7765 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 9.75 2623.2 - 7.02E+06 - - - 2.1591 - 1.355 0.07 - 176.4 1 2 0 0.0018 7 0 0 0 3.76E+08 3.78E+08 - - - 0.5201 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.10842.10842.2 0.00163 14-Aug K.MMDIVAAK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 877.4401 1.69 9928 10842 2 877.441299 439.7273 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.59 2624.9 - 277860 - - - 1.314 - 1.529 0.511 - 213.7 1 2 0 0.0012 8 0 0 0 1.52E+07 9.00E+06 - - - 4.0955 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.10844.10844.2 0.211 12-Aug R.MGLVMDR[166.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 830.4018 2.32 9930 10844 2 830.401207 416.2082 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2625.1 - 353245 - - - -0.7141 - 1.572 0.269 - 253.2 1 2 0 -0.0006 7 0 0 0 1.36E+09 5.86E+08 - - - 2.4609 0.9896 230117_WJC_METTL3_WT_vs_EV_F02.10848.10848.2 0.1 12-Apr K.VLPTIPK[136.11].E "sp|P35606|COPB2_HUMAN,sp|Q8ND07|BBOF1_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 5 774.5095 3.09 9931 10848 2 774.510378 388.262 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 8.72 2625.7 - 1.09E+06 - - - 1.1646 - 1.002 0.247 - 35.5 9 2 0 0.0009 7 0 0 0 1.69E+08 5.45E+07 - - - 0.4451 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.10852.10852.2 6.44E-06 20-Sep K.FGDPVVQSDMK.H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1221.57 0.75 9932 10852 2 1221.570312 611.7923 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.21 2626.3 - 287214 - - - 0.2767 - 1.552 0.369 - 213 1 2 0 0.0003 11 0 0 0 1.21E+07 1.61E+07 - - - 2.9554 0.9663 230117_WJC_METTL3_WT_vs_EV_F02.10855.10855.2 0.0018 13/16 R.PGPLLVSAR[166.11].R sp|Q9NUL7|DDX28_HUMAN 1 918.5526 9.69 9935 10855 2 918.554727 460.2836 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 10.18 2626.6 - 1.11E+06 - - - 2.2927 - 2.005 0.37 - 508 1 1 0 0.0021 9 0 0 0 7.00E+08 7.22E+07 - - - 3.7857 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.10860.10860.2 0.00374 12-Aug R.MGLVMDR.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 820.3935 2.32 9938 10860 2 820.393043 411.204 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2627.1 - 1.72E+06 - - - -0.5936 - 1.66 0.342 - 255.2 1 2 0 -0.0005 7 0 0 0 1.36E+09 5.86E+08 - - - 3.1727 1 230117_WJC_METTL3_WT_vs_EV_F02.10864.10864.2 2.12E-06 22-Sep R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 9939 10864 2 1474.77934 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2627.7 - 319593 - - - 0.9134 - 2.041 0.533 - 172.3 1 2 0 0.0013 12 0 0 0 3.63E+07 0.00E+00 - - - 4.8545 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.10895.10895.2 0.00671 20-Jul K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 4349.16 9943 10895 2 1106.546207 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2632.6 - 245380 - - - -0.1762 - 1.732 0.388 - 104.1 1 2 0 -0.0002 11 0 0 0 2.35E+09 5.41E+05 - - - 3.3926 0.9944 230117_WJC_METTL3_WT_vs_EV_F02.10910.10910.2 1.41 12-Jun R.LILPEAK.V "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN,tr|A8MSZ8|A8MSZ8_HUMAN" 3 782.4902 1.36 9945 10910 2 782.491042 392.2524 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 6 2634.9 - 1.43E+06 - - - 1.0876 - 1.064 0.225 - 124.5 1 2 0 0.0009 7 0 0 0 1.14E+08 8.38E+07 - - - 0.8991 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.10918.10918.2 0.0013 16-Aug K.EIAEAYLGK.T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 992.5179 10.52 9948 10918 2 992.518436 497.2662 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 2636 - 1.24E+06 - - - 0.5783 - 1.416 0.27 - 222.3 1 2 0 0.0006 9 0 0 0 6.15E+07 5.85E+06 - - - 2.0413 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.10928.10928.2 0.00532 14-Sep R.VITALVER.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 899.544 0.36 9950 10928 2 899.543828 450.7793 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2637.5 - 1.71E+06 - - - -0.2101 - 1.738 0.339 - 241.4 1 2 0 -0.0002 8 0 0 0 3.46E+09 9.59E+09 - - - 3.2118 0.9586 230117_WJC_METTL3_WT_vs_EV_F02.10934.10934.2 0.55 14-Jul R.VFVNPSLR[166.11].V sp|Q9HBH1|DEFM_HUMAN 1 940.537 1.05 9953 10934 2 940.537591 471.2758 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 9.72 2638.3 - 1.54E+06 - - - 0.6592 - 1.091 0.039 - 139.3 1 2 0 0.0006 8 0 0 0 4.00E+08 3.82E+08 - - - -0.4085 0.9353 230117_WJC_METTL3_WT_vs_EV_F02.10944.10944.2 2.77 14-Jun R.LLVVTDPR[166.11].A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 921.5523 3.09 9958 10944 2 921.550586 461.7834 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.84 2639.6 - 585193 - - - -1.8458 - 1.146 0.103 - 95.9 1 2 0 -0.0017 8 0 0 0 2.00E+09 6.46E+08 - - - 0.2122 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.10957.10957.2 0.0658 14-Jun R.AALLVPPR.Y sp|Q99959|PKP2_HUMAN 1 835.528 23.38 9965 10957 2 835.527196 418.7713 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 9.79 2641.2 - 458323 - - - -0.93 - 1.596 0.282 - 98.5 1 2 0 -0.0008 8 0 0 0 2.92E+08 1.25E+07 - - - 2.5336 0.9681 230117_WJC_METTL3_WT_vs_EV_F02.10958.10958.2 0.13 14-Jul R.AVAEMVLK[136.11].G sp|Q96CU9|FXRD1_HUMAN 1 867.4979 5.66 9966 10958 2 867.495947 434.7562 FAD-dependent oxidoreductase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FOXRED1 PE=1 SV=2 6.05 2641.3 - 351958 - - - -2.2801 - 1.154 0.197 - 145.6 1 2 0 -0.002 8 0 0 0 6.97E+07 1.23E+07 - - - 0.9274 0.9933 230117_WJC_METTL3_WT_vs_EV_F02.10967.10967.2 1.4 12-Jul R.LNELLVK.A "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L253|I3L253_HUMAN" 3 827.5117 2.13 9969 10967 2 827.511899 414.7631 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2642.6 - 1.43E+06 - - - 0.2961 - 1.642 0.073 - 169.4 3 2 0 0.0002 7 0 0 0 6.07E+08 2.84E+08 - - - 0.9383 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.10976.10976.2 0.0559 12-May K.AC[160.03]TILLR.G "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 845.4793 11.92 9972 10976 2 845.479957 423.7469 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 8.29 2643.8 - 3.47E+06 - - - 0.7664 - 1.257 0.218 - 144.8 1 2 0 0.0006 7 0 0 0 4.44E+08 3.72E+07 - - - 1.3757 0.9523 230117_WJC_METTL3_WT_vs_EV_F02.10995.10995.2 4.45 14-Jul K.ILPVGGIK.E "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN,tr|K7ERR6|K7ERR6_HUMAN" 4 795.5218 1.29 9976 10995 2 795.52146 398.7682 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 8.75 2646.6 - 963080 - - - -0.4588 - 1.128 0.06 - 92 1 2 0 -0.0004 8 0 0 0 5.39E+07 4.19E+07 - - - -0.1527 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.11001.11001.2 0.174 14-Aug R.AIVPLEAR.M "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 867.5178 1.86 9979 11001 2 867.520055 434.7662 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 6.05 2647.4 - 229628 - - - 2.5971 - 1.455 0.226 - 253.1 1 2 0 0.0023 8 0 0 0 1.02E+08 5.48E+07 - - - 1.8405 0.936 230117_WJC_METTL3_WT_vs_EV_F02.11019.11019.2 0.0621 14-Aug Q.VLVLAPTR[166.11].E "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 877.5625 0.91 9984 11019 2 877.563356 439.7885 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.72 2650 - 798948 - - - 1.0233 - 1.632 0.278 - 294.6 1 1 0 0.0009 8 0 0 0 1.19E+08 1.30E+08 - - - 2.5713 0.999 230117_WJC_METTL3_WT_vs_EV_F02.11021.11021.2 0.0436 14-Aug R.VITALVER[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 909.5523 0.36 9985 11021 2 909.553015 455.7834 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2650.2 - 5.90E+07 - - - 0.8004 - 1.533 0.291 - 263.4 1 2 0 0.0007 8 0 0 0 3.46E+09 9.58E+09 - - - 2.4786 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.11026.11026.2 0.0151 14-Aug R.NSLYDMAR.Y "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 968.4386 2.6 9987 11026 2 968.439581 485.2266 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.84 2650.9 - 122424 - - - 1.0481 - 1.529 0.321 - 198.4 1 2 0 0.001 8 0 0 0 4.25E+06 1.63E+06 - - - 2.6922 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.11028.11028.2 0.00382 22-Sep K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 2.31 9989 11028 2 1222.665527 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2651.1 - 75929.8 - - - 0.5398 - 1.898 0.374 - 196.2 1 2 0 0.0007 12 0 0 0 9.43E+07 4.07E+07 - - - 3.4892 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.11031.11031.2 0.00219 14-Jun R.VFVNPSLR.V sp|Q9HBH1|DEFM_HUMAN 1 930.5287 1.05 9990 11031 2 930.529516 466.2716 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 9.72 2651.6 - 603541 - - - 0.8758 - 1.525 0.184 - 137.3 2 2 0 0.0008 8 0 0 0 4.00E+08 3.82E+08 - - - 1.538 1 230117_WJC_METTL3_WT_vs_EV_F02.11041.11041.2 3.61E-05 22-Dec K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 2.31 9993 11041 2 1214.652363 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2652.9 - 451705 - - - 1.3963 - 2.418 0.446 - 493.9 1 2 0 0.0017 12 0 0 0 9.47E+07 4.10E+07 - - - 4.6578 0.991 230117_WJC_METTL3_WT_vs_EV_F02.11048.11048.2 0.193 12-Jul R.LISVLNK.S "sp|Q9Y450|HBS1L_HUMAN,tr|H0YDX7|H0YDX7_HUMAN,tr|B7Z524|B7Z524_HUMAN,tr|J3QT46|J3QT46_HUMAN" 4 785.5011 0.47 9997 11048 2 785.502777 393.7578 HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1 8.75 2653.8 - 791199 - - - 2.1477 - 1.386 0.079 - 107.5 1 2 0 0.0017 7 0 0 0 3.60E+07 7.70E+07 - - - 0.6583 0.9075 230117_WJC_METTL3_WT_vs_EV_F02.11049.11049.2 1.13 12-Jun R.LIPTELR[166.11].R "sp|Q96G21|IMP4_HUMAN,tr|F8WCN0|F8WCN0_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN" 4 850.5152 1.32 9998 11049 2 850.519355 426.2649 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2654 - 171985 - - - 4.917 - 1.19 0.123 - 111 5 2 0 0.0042 7 0 0 0 2.40E+08 1.82E+08 - - - 0.1871 0.9962 230117_WJC_METTL3_WT_vs_EV_F02.11065.11065.2 0.0526 18-Jul K.STVVPVPYEK.M "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1117.6019 1.02 10005 11065 2 1117.603185 559.8082 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.72 2656.1 - 256262 - - - 1.1265 - 1.208 0.221 - 162.5 1 2 0 0.0013 10 0 0 0 1.52E+07 1.49E+07 - - - 1.2004 0.9112 230117_WJC_METTL3_WT_vs_EV_F02.11075.11075.2 5.77 12-Apr R.NMAPDLR[166.11].Q "sp|P35611|ADDA_HUMAN,tr|E7EV99|E7EV99_HUMAN,tr|E7ENY0|E7ENY0_HUMAN,tr|A0A804HL01|A0A804HL01_HUMAN,tr|A0A0A0MSR2|A0A0A0MSR2_HUMAN,tr|D6RAH3|D6RAH3_HUMAN,tr|D6RF25|D6RF25_HUMAN,tr|D6RJE2|D6RJE2_HUMAN" 8 825.4042 0.57 10009 11075 2 825.406245 413.7094 Alpha-adducin OS=Homo sapiens OX=9606 GN=ADD1 PE=1 SV=2 5.84 2657.5 - 1.07E+06 - - - 2.4255 - 0.97 0.071 - 35.7 4 2 0 0.002 7 0 0 0 4.63E+07 8.09E+07 - - - -0.8007 0.8786 230117_WJC_METTL3_WT_vs_EV_F02.11077.11077.2 5 12-May R.LISVLNK[136.11].S "sp|Q9Y450|HBS1L_HUMAN,tr|H0YDX7|H0YDX7_HUMAN,tr|B7Z524|B7Z524_HUMAN,tr|J3QT46|J3QT46_HUMAN" 4 793.5153 0.47 10010 11077 2 793.517072 397.7649 HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1 8.75 2657.8 - 535912 - - - 2.2457 - 0.95 0.026 - 58.4 2 2 0 0.0018 7 0 0 0 3.60E+07 7.71E+07 - - - -1.0645 0.9963 230117_WJC_METTL3_WT_vs_EV_F02.11089.11089.2 0.187 12-Jun R.LIPTELR.R "sp|Q96G21|IMP4_HUMAN,tr|F8WCN0|F8WCN0_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN" 4 840.5069 1.05 10016 11089 2 840.508125 421.2607 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2659.3 - 2.10E+06 - - - 1.4539 - 1.236 0.203 - 163.8 1 2 0 0.0012 7 0 0 0 1.83E+08 1.74E+08 - - - 1.2113 0.988 230117_WJC_METTL3_WT_vs_EV_F02.11107.11107.2 0.373 18-Jun K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 2.1 10020 11107 2 1008.598657 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2662.1 - 192922 - - - 1.86 - 1.163 0.144 - 64.5 2 2 0 0.0019 10 0 0 0 1.32E+07 6.29E+06 - - - 0.391 0.9939 230117_WJC_METTL3_WT_vs_EV_F02.11115.11115.2 4.7 12-Jun K.IIPVVVK[136.11].M "sp|Q96KG9|SCYL1_HUMAN,tr|E9PPN3|E9PPN3_HUMAN,tr|E9PK59|E9PK59_HUMAN,tr|E9PS17|E9PS17_HUMAN" 4 774.5459 1.64 10023 11115 2 774.546767 388.2802 N-terminal kinase-like protein OS=Homo sapiens OX=9606 GN=SCYL1 PE=1 SV=1 8.75 2663.2 - 598636 - - - 1.1697 - 1.016 0.235 - 86.6 1 2 0 0.0009 7 0 0 0 4.52E+07 2.76E+07 - - - 0.8267 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.11126.11126.2 0.145 14-Jul K.GIYALAAR.D "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 833.4759 0.85 10027 11126 2 833.477602 417.7452 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 8.75 2664.6 - 699714 - - - 1.9965 - 1.327 0.242 - 131.3 1 2 0 0.0017 8 0 0 0 6.43E+07 7.59E+07 - - - 1.6812 0.9938 230117_WJC_METTL3_WT_vs_EV_F02.11128.11128.2 1.16 12-Jul K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 0.96 10029 11128 2 828.474957 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2664.8 - 1.31E+06 - - - 1.9904 - 1.455 0.09 - 181.4 1 2 0 0.0016 7 0 0 0 3.45E+10 3.58E+10 - - - 0.8934 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.11132.11132.2 0.263 20-Jul K.IGGIGTVPVGR.V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1024.6029 4.6 10031 11132 2 1024.605258 513.3087 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2665.5 - 355874 - - - 2.2731 - 1.666 0.328 - 109.1 1 2 0 0.0023 11 0 0 0 8.34E+07 1.81E+07 - - - 2.8437 0.962 230117_WJC_METTL3_WT_vs_EV_F02.11135.11135.2 7.97 12-May K.FIEIAAR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 818.465 0.96 10032 11135 2 818.464782 410.2398 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2665.9 - 3.23E+06 - - - -0.3128 - 1.016 0.144 - 60.5 3 2 0 -0.0003 7 0 0 0 3.46E+10 3.58E+10 - - - -0.0583 0.9933 230117_WJC_METTL3_WT_vs_EV_F02.11185.11185.2 0.0204 14-Sep K.IGVTVLSR.L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 843.5178 0.93 10048 11185 2 843.514993 422.7662 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2673 - 3.88E+06 - - - -3.3301 - 1.813 0.301 - 270.3 1 2 0 -0.0028 8 0 0 0 4.64E+08 5.01E+08 - - - 3.0577 0.9756 230117_WJC_METTL3_WT_vs_EV_F02.11208.11208.2 0.557 14-Jul R.ILMGSTLR[166.11].K "sp|P10644|KAP0_HUMAN,sp|P31321|KAP1_HUMAN,tr|K7EM13|K7EM13_HUMAN,tr|C9JSK5|C9JSK5_HUMAN,tr|K7EKR1|K7EKR1_HUMAN,tr|K7EPB2|K7EPB2_HUMAN,tr|H7BYW5|H7BYW5_HUMAN" 7 899.5138 1.65 10055 11208 2 899.51258 450.7642 cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1A PE=1 SV=1 9.75 2676.3 - 845743 - - - -1.3485 - 1.267 0.127 - 123.1 1 2 0 -0.0012 8 0 0 0 3.98E+07 2.41E+07 - - - 0.6924 0.9898 230117_WJC_METTL3_WT_vs_EV_F02.11214.11214.2 0.689 12-Jul R.VYLGALK[136.11].Y sp|Q6P2Q9|PRP8_HUMAN 1 770.4782 1.03 10057 11214 2 770.477297 386.2464 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.56 2677 - 1.97E+06 - - - -1.1408 - 1.457 0.139 - 182.2 1 2 0 -0.0009 7 0 0 0 2.37E+08 2.31E+08 - - - 1.26 0.9814 230117_WJC_METTL3_WT_vs_EV_F02.11228.11228.2 6.06 12-Sep K.LGITQLR.F "sp|Q9Y285|SYFA_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 3 799.4916 2.63 10059 11228 2 799.490594 400.7531 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 9.75 2679.2 - 3.10E+06 - - - -1.2433 - 1.766 0 - 233 1 2 0 -0.001 7 0 0 0 1.62E+08 6.16E+07 - - - 0.8427 0.9945 230117_WJC_METTL3_WT_vs_EV_F02.11236.11236.2 0.199 12-Jul R.VTVPLVR.R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 782.5014 0.97 10062 11236 2 782.500837 392.258 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2680.3 - 4.68E+06 - - - -0.7502 - 1.388 0.201 - 193.3 1 2 0 -0.0006 7 0 0 0 4.31E+08 4.45E+08 - - - 1.5643 0.9226 230117_WJC_METTL3_WT_vs_EV_F02.11254.11254.2 0.315 14-Aug K.LVPVLSAK[136.11].A "sp|P37837|TALDO_HUMAN,tr|F2Z393|F2Z393_HUMAN" 2 833.5466 1.44 10065 11254 2 833.544474 417.7806 Transaldolase OS=Homo sapiens OX=9606 GN=TALDO1 PE=1 SV=2 8.75 2683.1 - 851049 - - - -2.5386 - 1.074 0.152 - 155.7 1 2 0 -0.0021 8 0 0 0 5.27E+07 3.66E+07 - - - 0.3783 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.11264.11264.2 0.291 12-Jun R.VTVPLVR[166.11].R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 792.5097 0.97 10068 11264 2 792.510529 397.2621 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2684.5 - 9.50E+06 - - - 1.0536 - 1.382 0.213 - 152.4 1 2 0 0.0008 7 0 0 0 4.31E+08 4.44E+08 - - - 1.6391 0.9315 230117_WJC_METTL3_WT_vs_EV_F02.11268.11268.2 0.0344 14-Sep K.LTGVFAPR.P "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 859.4916 1.02 10070 11268 2 859.491578 430.7531 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2685 - 6.63E+06 - - - -0.0116 - 1.832 0.279 - 344 1 1 0 0 8 0 0 0 2.29E+09 2.25E+09 - - - 2.9276 0.9905 230117_WJC_METTL3_WT_vs_EV_F02.11270.11270.2 0.508 12-Jun K.LPYSTFR.T "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 882.46 1.18 10072 11270 2 882.460923 442.2373 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.75 2685.2 - 590924 - - - 1.0992 - 1.06 0.175 - 157.5 1 2 0 0.001 7 0 0 0 1.82E+08 1.54E+08 - - - 0.5179 0.9915 230117_WJC_METTL3_WT_vs_EV_F02.11280.11280.2 0.696 12-Jun K.LPYSTFR[166.11].T "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 892.4682 1.18 10076 11280 2 892.469784 447.2414 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.75 2686.7 - 1.45E+06 - - - 1.7491 - 1.075 0.182 - 112.7 1 2 0 0.0016 7 0 0 0 1.82E+08 1.53E+08 - - - 0.6139 0.9883 230117_WJC_METTL3_WT_vs_EV_F02.11290.11290.2 0.115 14-Sep K.VGDFGLAR.E "sp|P21127|CD11B_HUMAN,sp|Q9UQ88|CD11A_HUMAN,sp|Q13882|PTK6_HUMAN,tr|Q5QPR4|Q5QPR4_HUMAN,tr|A0A0D9SER5|A0A0D9SER5_HUMAN,tr|A0A0D9SEN2|A0A0D9SEN2_HUMAN,tr|Q5QPR3|Q5QPR3_HUMAN,tr|A0A0D9SEI3|A0A0D9SEI3_HUMAN" 8 833.4396 1.33 10081 11290 2 833.442217 417.7271 Cyclin-dependent kinase 11B OS=Homo sapiens OX=9606 GN=CDK11B PE=1 SV=4 5.81 2688 - 329858 - - - 3.1976 - 1.494 0.085 - 220.9 1 2 0 0.0027 8 0 0 0 1.08E+07 8.11E+06 - - - 0.8787 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.11321.11321.2 0.0257 18-Jul K.NGQDLGVAFK[136.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1055.5491 1.46 10091 11321 2 1055.549907 528.7818 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2692.6 - 183149 - - - 0.756 - 1.653 0.26 - 152 1 2 0 0.0008 10 0 0 0 6.06E+07 4.15E+07 - - - 2.364 0.962 230117_WJC_METTL3_WT_vs_EV_F02.11330.11330.2 1.18 12-Jul R.LIVNIAK[136.11].V sp|Q15058|KIF14_HUMAN 1 777.5204 1.59 10096 11330 2 777.521402 389.7675 Kinesin-like protein KIF14 OS=Homo sapiens OX=9606 GN=KIF14 PE=1 SV=1 8.75 2693.7 - 534437 - - - 1.3209 - 0.986 0.079 - 86 1 2 0 0.001 7 0 0 0 1.79E+07 1.13E+07 - - - -0.4205 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.11339.11339.2 0.882 12-Jul K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 1.56 10099 11339 2 828.474585 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2694.9 - 2.91E+06 - - - 1.5414 - 1.525 0.162 - 192.4 1 2 0 0.0013 7 0 0 0 3.18E+08 2.04E+08 - - - 1.5742 0.9543 230117_WJC_METTL3_WT_vs_EV_F02.11347.11347.2 0.37 12-Jun K.FIEIAAR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 818.465 1.07 10102 11347 2 818.467086 410.2398 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2696 - 2.54E+06 - - - 2.5022 - 1.31 0.005 - 86.2 4 2 0 0.002 7 0 0 0 1.62E+08 1.51E+08 - - - -0.3361 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.11354.11354.2 0.0465 12-Jul K.FMTDPIR.L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 878.432 0.94 10104 11354 2 878.43354 440.2233 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2697 - 1.29E+06 - - - 1.7258 - 1.239 0.259 - 236.3 1 2 0 0.0015 7 0 0 0 1.36E+08 1.45E+08 - - - 1.6325 0.992 230117_WJC_METTL3_WT_vs_EV_F02.11356.11356.2 0.8 14-Jul R.NLLLAGAK[136.11].V sp|Q9P2R3|ANFY1_HUMAN 1 806.5105 4.2 10105 11356 2 806.511627 404.2625 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 8.75 2697.2 - 368077 - - - 1.349 - 1.514 0.045 - 151.1 1 2 0 0.0011 8 0 0 0 9.16E+07 2.18E+07 - - - 0.6239 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.11360.11360.2 2.58 14-Aug K.FGPALSVK[136.11].V "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 825.484 3.95 10106 11360 2 825.485933 413.7493 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.75 2697.8 - 2.30E+06 - - - 2.3538 - 1.77 0.144 - 185.6 1 2 0 0.0019 8 0 0 0 3.01E+09 7.64E+08 - - - 1.826 0.8478 230117_WJC_METTL3_WT_vs_EV_F02.11367.11367.2 2.38 14-Apr R.AALLVPPR.Y sp|Q99959|PKP2_HUMAN 1 835.528 8.22 10109 11367 2 835.527914 418.7713 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 9.79 2698.6 - 227605 - - - -0.0706 - 1.003 0.085 - 23.3 51 2 0 -0.0001 8 0 0 0 1.77E+07 2.15E+06 - - - -1.0849 1 230117_WJC_METTL3_WT_vs_EV_F02.11371.11371.2 7.84E-08 18-Dec K.NGQDLGVAFK.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1047.5349 1.63 10110 11371 2 1047.537314 524.7747 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2699.2 - 1.01E+06 - - - 2.2959 - 2.544 0.56 - 719.5 1 2 0 0.0024 10 0 0 0 6.78E+07 4.15E+07 - - - 5.7828 0.9835 230117_WJC_METTL3_WT_vs_EV_F02.11378.11378.2 1.35 12-May K.FMTDPIR[166.11].L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 888.4403 1.01 10113 11378 2 888.442392 445.2274 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2700.1 - 2.57E+06 - - - 2.3614 - 0.829 0.251 - 87.5 1 2 0 0.0021 7 0 0 0 1.46E+08 1.44E+08 - - - 0.3 0.9935 230117_WJC_METTL3_WT_vs_EV_F02.11380.11380.2 0.194 14-Aug K.ALSVGLVK.G "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 3 785.5011 1.64 10114 11380 2 785.502707 393.7578 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 8.8 2700.5 - 702239 - - - 2.0586 - 1.381 0.116 - 179 1 2 0 0.0016 8 0 0 0 1.26E+08 7.65E+07 - - - 0.8708 0.9946 230117_WJC_METTL3_WT_vs_EV_F02.11386.11386.2 0.149 14-Jun K.VLEC[160.03]DIIK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 988.5263 0.4 10118 11386 2 988.526731 495.2704 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 2701.1 - 270091 - - - 0.4178 - 1.262 0.179 - 92.2 1 2 0 0.0004 8 0 0 0 1.11E+07 2.76E+07 - - - 1.0648 0.9485 230117_WJC_METTL3_WT_vs_EV_F02.11388.11388.2 2.38 20-Jun K.ETTIDGEELVK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1240.6278 1.39 10119 11388 2 1240.631851 621.3212 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4 2701.3 - 165140 - - - 3.2548 - 1.084 0.082 - 107.5 1 2 0 0.004 11 0 0 0 5.47E+06 3.93E+06 - - - -0.1364 0.9947 230117_WJC_METTL3_WT_vs_EV_F02.11397.11397.2 2.15 14-Jul R.VLAVTAIR.E sp|P22102|PUR2_HUMAN 1 841.5385 2.46 10122 11397 2 841.539928 421.7765 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2702.6 - 2.33E+06 - - - 1.6517 - 1.518 0.087 - 208.1 1 2 0 0.0014 8 0 0 0 3.93E+08 1.60E+08 - - - 0.942 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.11403.11403.2 0.125 12-Aug R.IVYLYTK[136.11].K sp|P49207|RL34_HUMAN 1 906.5306 0.73 10125 11403 2 906.532329 454.2726 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 8.5 2703.3 - 7.12E+06 - - - 1.9018 - 1.642 0.348 - 233.2 1 2 0 0.0017 7 0 0 0 9.02E+08 1.23E+09 - - - 3.1821 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.11404.11404.2 1.15 14-Aug R.VLAVTAIR[166.11].E sp|P22102|PUR2_HUMAN 1 851.5468 2.46 10126 11404 2 851.548506 426.7807 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2703.4 - 1.51E+06 - - - 1.994 - 1.749 0.105 - 205.3 1 2 0 0.0017 8 0 0 0 3.93E+08 1.60E+08 - - - 1.502 0.9955 230117_WJC_METTL3_WT_vs_EV_F02.11428.11428.2 0.0366 18-May K.C[160.03]PFTGNVSIR[166.11].G "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1159.5683 1.04 10136 11428 2 1159.571196 580.7915 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.25 2706.6 - 115980 - - - 2.4561 - 1.086 0.274 - 78.3 1 2 0 0.0028 10 0 0 0 4.25E+06 4.09E+06 - - - 1.2942 0.9932 230117_WJC_METTL3_WT_vs_EV_F02.11430.11430.2 0.142 12-Jun K.MMEIMTR.E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 910.4075 0.83 10137 11430 2 910.407476 456.211 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2706.8 - 2.96E+06 - - - 0.0121 - 1.079 0.236 - 74.7 1 2 0 0 7 0 0 0 1.49E+08 1.79E+08 - - - 1.025 0.9627 230117_WJC_METTL3_WT_vs_EV_F02.11432.11432.2 3.22 14-Jul K.IVGYVLAK.M "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN" 4 861.5324 1.43 10138 11432 2 861.532302 431.7735 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 8.59 2707 - 566093 - - - -0.1021 - 0.976 0.123 - 82.3 1 2 0 -0.0001 8 0 0 0 1.91E+08 1.34E+08 - - - -0.1238 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.11435.11435.2 0.0024 12-Jul K.MMEIMTR[166.11].E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 920.4157 0.83 10139 11435 2 920.416173 461.2151 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2707.4 - 1.32E+06 - - - 0.4759 - 1.479 0.16 - 231.3 1 2 0 0.0004 7 0 0 0 1.49E+08 1.79E+08 - - - 1.4627 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.11437.11437.2 0.0936 16-Sep R.MVGGVLVER[166.11].T sp|Q9UHV9|PFD2_HUMAN 1 968.5353 0.35 10141 11437 2 968.537272 485.2749 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 5.75 2707.6 - 1.42E+06 - - - 2.0805 - 1.543 0.245 - 184.2 1 2 0 0.002 9 0 0 0 8.98E+07 2.55E+08 - - - 2.1047 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.11438.11438.2 0.909 18-Sep K.YEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1178.5932 245.94 10142 11438 2 1178.592811 590.3039 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2707.8 - 115328 - - - -0.2893 - 1.96 0.257 - 352.1 1 2 0 -0.0003 10 0 0 0 2.65E+07 1.08E+05 - - - 2.8175 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.11443.11443.2 0.00119 12-Jul K.MMVAGFK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 790.3961 0.87 10144 11443 2 790.396895 396.2053 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2708.4 - 1.89E+06 - - - 1.0033 - 1.541 0.5 - 239.9 1 2 0 0.0008 7 0 0 0 5.73E+09 6.57E+09 - - - 4.1039 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.11452.11452.2 0.000408 12-Jul K.MMVAGFK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 782.3819 0.87 10146 11452 2 782.382636 392.1982 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2709.7 - 3.24E+06 - - - 0.9382 - 1.588 0.484 - 212.3 1 2 0 0.0007 7 0 0 0 5.73E+09 6.57E+09 - - - 4.081 0.998 230117_WJC_METTL3_WT_vs_EV_F02.11455.11455.2 0.797 14-Aug K.IVGYVLAK[136.11].M "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN" 4 869.5466 1.43 10147 11455 2 869.547338 435.7806 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 8.59 2710.1 - 1.86E+06 - - - 0.8602 - 1.265 0.271 - 150.8 1 2 0 0.0007 8 0 0 0 1.91E+08 1.34E+08 - - - 1.7513 0.9385 230117_WJC_METTL3_WT_vs_EV_F02.11466.11466.2 11.5 14-Aug R.K[136.11]QNLLASR.E "sp|O00555|CAC1A_HUMAN,tr|A0A1B0GTI4|A0A1B0GTI4_HUMAN,tr|A0A1C7CYY9|A0A1C7CYY9_HUMAN,tr|A0A1B0GU81|A0A1B0GU81_HUMAN,tr|A0A590UJK2|A0A590UJK2_HUMAN,tr|B5TYJ1|B5TYJ1_HUMAN,tr|A0A1B0GTW2|A0A1B0GTW2_HUMAN,tr|A0A384DVW2|A0A384DVW2_HUMAN,tr|A0A1B0GTN7|A0A1B0GTN7_HUMAN,tr|A0A087WW63|A0A087WW63_HUMAN,tr|A0A1B0GU74|A0A1B0GU74_HUMAN,tr|A0A1B0GUS3|A0A1B0GUS3_HUMAN" 12 936.5596 - 10149 11466 2 936.560531 469.2871 Voltage-dependent P\Q-type calcium channel subunit alpha-1A OS=Homo sapiens OX=9606 GN=CACNA1A PE=1 SV=3 11 2711.9 - 1.03E+06 - - - 0.9791 - 1.07 0.048 - 95.5 5 2 0 0.0009 8 0 0 0 - - - - - -0.7129 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.11474.11474.3 0.000163 Oct-52 K.SQIHDIVLVGGSTR.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1480.7998 31.96 10151 11474 3 1480.80248 494.6072 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2713.1 - 224014 - - - 1.8159 - 2.094 0.429 - 136.3 1 2 0 0.0027 14 0 0 0 1.60E+07 5.00E+05 - - - 5.2863 0.965 230117_WJC_METTL3_WT_vs_EV_F02.11480.11480.2 1.21 14-Jun R.GLGGIMVK.R sp|O94776|MTA2_HUMAN 1 773.4469 1.23 10154 11480 2 773.44837 387.7307 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 2713.9 - 973308 - - - 1.8411 - 1.076 0.074 - 100.2 2 2 0 0.0014 8 0 0 0 4.75E+07 3.85E+07 - - - -0.3264 0.9285 230117_WJC_METTL3_WT_vs_EV_F02.11524.11524.2 5.67 12-Jul K.LAPFIAK[136.11].R "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN,tr|K7ELX4|K7ELX4_HUMAN" 3 766.4833 1.7 10166 11524 2 766.481782 384.2489 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 8.75 2720.2 - 1.94E+06 - - - -1.9296 - 1.286 0.046 - 131.3 1 2 0 -0.0015 7 0 0 0 3.94E+08 2.31E+08 - - - 0.1773 0.9945 230117_WJC_METTL3_WT_vs_EV_F02.11551.11551.2 0.893 14-Aug R.TIAPIIGR.T sp|Q99459|CDC5L_HUMAN 1 839.5229 1.17 10175 11551 2 839.522682 420.7687 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.41 2724 - 604390 - - - -0.2454 - 1.318 0.194 - 203.4 1 2 0 -0.0002 8 0 0 0 2.51E+07 2.14E+07 - - - 1.3066 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.11561.11561.2 0.0135 16-Oct R.LLSPLSSAR[166.11].L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 952.5581 1.13 10178 11561 2 952.556943 477.2863 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 2725.5 - 897667 - - - -1.2157 - 1.752 0.318 - 269.6 1 2 0 -0.0012 9 0 0 0 2.04E+08 1.81E+08 - - - 3.0117 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.11578.11578.2 0.00329 16-Sep R.LLPAELPAK[136.11].R sp|P78527|PRKDC_HUMAN 1 958.5943 1.17 10188 11578 2 958.597742 480.3044 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2727.5 - 562703 - - - 3.6241 - 1.67 0.326 - 239.5 1 2 0 0.0035 9 0 0 0 5.29E+07 4.51E+07 - - - 2.9314 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.11587.11587.2 0.0234 16-Sep R.LLSPLSSAR.L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 942.5498 1.12 10192 11587 2 942.550041 472.2822 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 2728.6 - 2.97E+06 - - - 0.2228 - 1.835 0.286 - 292.9 1 2 0 0.0002 9 0 0 0 2.04E+08 1.81E+08 - - - 2.9095 0.932 230117_WJC_METTL3_WT_vs_EV_F02.11590.11590.2 0.12 16-Sep N.LVIITAGAR.Q "sp|Q9BYZ2|LDH6B_HUMAN,sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 7 912.5757 0.97 10193 11590 2 912.576839 457.2951 L-lactate dehydrogenase A-like 6B OS=Homo sapiens OX=9606 GN=LDHAL6B PE=1 SV=3 9.75 2729.1 - 1.42E+06 - - - 1.3007 - 1.771 0.241 - 287.6 1 1 0 0.0012 9 0 0 0 1.84E+08 1.89E+08 - - - 2.4742 0.98 230117_WJC_METTL3_WT_vs_EV_F02.11596.11596.2 4.21 12-Jun K.IIDDLLK[136.11].N "sp|Q9H227|GBA3_HUMAN,tr|A0A087WTY7|A0A087WTY7_HUMAN" 2 836.5099 1.04 10197 11596 2 836.510816 419.2622 Cytosolic beta-glucosidase OS=Homo sapiens OX=9606 GN=GBA3 PE=1 SV=2 4.21 2729.7 - 945566 - - - 1.1309 - 1.309 0.044 - 64.7 3 2 0 0.0009 7 0 0 0 7.05E+08 6.79E+08 - - - 0.0057 0.9754 230117_WJC_METTL3_WT_vs_EV_F02.11600.11600.2 3.33 14-May R.IGLETSLR[166.11].Y sp|Q9Y230|RUVB2_HUMAN 1 897.5159 1.61 10199 11600 2 897.51685 449.7652 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6 2730.1 - 262518 - - - 1.0562 - 1.13 0.092 - 46.9 3 2 0 0.0009 8 0 0 0 4.23E+07 2.62E+07 - - - -0.1243 0.937 230117_WJC_METTL3_WT_vs_EV_F02.11605.11605.2 0.0154 16-Sep N.LVIITAGAR[166.11].Q "sp|Q9BYZ2|LDH6B_HUMAN,sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 7 922.5839 0.97 10201 11605 2 922.585682 462.2992 L-lactate dehydrogenase A-like 6B OS=Homo sapiens OX=9606 GN=LDHAL6B PE=1 SV=3 9.75 2730.8 - 3.61E+06 - - - 1.9077 - 1.768 0.266 - 277 1 1 0 0.0018 9 0 0 0 1.84E+08 1.89E+08 - - - 2.6537 0.9945 230117_WJC_METTL3_WT_vs_EV_F02.11618.11618.2 0.313 12-Jul R.IDGVLIR.M sp|O75663|TIPRL_HUMAN 1 784.4807 2.54 10206 11618 2 784.481548 393.2476 TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2 5.84 2732.5 - 1.25E+06 - - - 1.095 - 1.382 0.114 - 110.8 1 2 0 0.0009 7 0 0 0 8.27E+07 3.25E+07 - - - 0.9079 0.9925 230117_WJC_METTL3_WT_vs_EV_F02.11629.11629.2 0.972 12-Jul R.VAGIFPR[166.11].L "sp|O96005|CLPT1_HUMAN,tr|K7EJ16|K7EJ16_HUMAN" 2 768.4522 0.79 10210 11629 2 768.452637 385.2334 Cleft lip and palate transmembrane protein 1 OS=Homo sapiens OX=9606 GN=CLPTM1 PE=1 SV=1 9.72 2733.9 - 1.08E+06 - - - 0.596 - 1.238 0.142 - 171.2 1 2 0 0.0005 7 0 0 0 6.04E+07 7.60E+07 - - - 0.7661 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.11635.11635.2 0.00141 14-Aug R.FGPLASVK.L "sp|O15042|SR140_HUMAN,tr|E7EW00|E7EW00_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H0Y8D9|H0Y8D9_HUMAN" 4 817.4698 0.15 10212 11635 2 817.470589 409.7422 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 8.75 2734.8 - 1.97E+06 - - - 0.9774 - 1.686 0.347 - 200.7 1 2 0 0.0008 8 0 0 0 1.36E+08 9.18E+08 - - - 3.1791 0.966 230117_WJC_METTL3_WT_vs_EV_F02.11656.11656.2 5.84 12-Jul R.FPGAYLK[136.11].G "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 802.4469 1.5 10219 11656 2 802.448843 402.2307 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.59 2737.9 - 755852 - - - 2.4513 - 1.104 0.066 - 131 1 2 0 0.002 7 0 0 0 1.07E+08 7.17E+07 - - - -0.1586 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.11663.11663.2 0.147 14-Jul R.MVLVGDVK.D "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PEU0|A0A6Q8PEU0_HUMAN,tr|A0A6Q8PHI4|A0A6Q8PHI4_HUMAN,tr|A0A6Q8PG82|A0A6Q8PG82_HUMAN" 7 859.4837 2.02 10221 11663 2 859.484379 430.7491 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 5.59 2738.8 - 1.64E+06 - - - 0.7609 - 1.33 0.267 - 174.5 1 2 0 0.0007 8 0 0 0 2.36E+08 1.17E+08 - - - 1.8729 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.11673.11673.2 0.0223 14-Sep R.MVLVGDVK[136.11].D "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PEU0|A0A6Q8PEU0_HUMAN,tr|A0A6Q8PHI4|A0A6Q8PHI4_HUMAN,tr|A0A6Q8PG82|A0A6Q8PG82_HUMAN" 7 867.4979 2.02 10224 11673 2 867.498242 434.7562 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 5.59 2740.2 - 1.60E+06 - - - 0.3654 - 1.891 0.35 - 327.5 1 2 0 0.0003 8 0 0 0 2.36E+08 1.17E+08 - - - 3.5475 0.9857 230117_WJC_METTL3_WT_vs_EV_F02.11678.11678.2 3.84 14-Aug K.NIILGGVK.A "sp|P22314|UBA1_HUMAN,tr|Q5JRS3|Q5JRS3_HUMAN,tr|Q5JRS2|Q5JRS2_HUMAN,tr|Q5JRS0|Q5JRS0_HUMAN,tr|Q5JRS1|Q5JRS1_HUMAN,tr|Q5JRR9|Q5JRR9_HUMAN" 6 812.512 2.46 10226 11678 2 812.513077 407.2633 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 8.75 2741 - 273317 - - - 1.3391 - 1.211 0.082 - 157.5 1 2 0 0.0011 8 0 0 0 3.92E+07 1.59E+07 - - - 0.2237 0.9942 230117_WJC_METTL3_WT_vs_EV_F02.11688.11688.2 0.24 14-Jun K.MVSAAFMK.K "sp|P25205|MCM3_HUMAN,tr|Q7Z6P5|Q7Z6P5_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 4 883.4296 2.91 10230 11688 2 883.430595 442.7221 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 8.5 2742.2 - 1.46E+06 - - - 1.1478 - 1.226 0.193 - 132.6 3 2 0 0.001 8 0 0 0 5.69E+07 1.96E+07 - - - 0.8676 0.9951 230117_WJC_METTL3_WT_vs_EV_F02.11691.11691.2 0.921 14-Jun R.LVSLIGSK.T "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 815.5117 1.95 10231 11691 2 815.512547 408.7631 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 2742.6 - 366128 - - - 1.095 - 1.335 0.148 - 92 1 2 0 0.0009 8 0 0 0 7.64E+07 3.93E+07 - - - 1.0053 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.11693.11693.2 0.192 14-Aug K.LINAVELK[136.11].K sp|P56192|SYMC_HUMAN 1 906.563 1.08 10233 11693 2 906.564737 454.2888 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6 2742.8 - 3.02E+06 - - - 1.9513 - 1.626 0.209 - 164.8 1 2 0 0.0018 8 0 0 0 2.23E+08 2.06E+08 - - - 2.0502 1 230117_WJC_METTL3_WT_vs_EV_F02.11696.11696.3 1.56E-10 14/84 K.DHTPSQELALTQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2270.0411 173.84 10234 11696 3 2270.042167 757.6876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2743.2 - 171982 - - - 0.4714 - 3.305 0.676 - 116.9 1 2 0 0.0011 22 0 0 0 5.87E+06 3.38E+04 - - - 8.9106 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.11698.11698.2 0.000396 16-Sep K.NDLAVVDVR[166.11].L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1009.5432 0.75 10235 11698 2 1009.545846 505.7789 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.21 2743.4 - 467658 - - - 2.6418 - 1.721 0.283 - 356.3 1 2 0 0.0027 9 0 0 0 1.50E+07 1.99E+07 - - - 2.7011 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.11702.11702.2 0.275 14-Sep R.LLGQIVDR[166.11].C sp|Q96I24|FUBP3_HUMAN 1 922.5475 1.48 10237 11702 2 922.549048 462.281 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2743.9 - 5.71E+06 - - - 1.6389 - 1.775 0.196 - 267.9 1 2 0 0.0015 8 0 0 0 1.16E+09 7.84E+08 - - - 2.2187 0.9675 230117_WJC_METTL3_WT_vs_EV_F02.11703.11703.2 4.3 16-Jun R.LILENHAAK[136.11].L "sp|Q9ULL1|PKHG1_HUMAN,tr|H0YD71|H0YD71_HUMAN" 2 1015.5906 0.01 10238 11703 2 1015.593341 508.8026 Pleckstrin homology domain-containing family G member 1 OS=Homo sapiens OX=9606 GN=PLEKHG1 PE=1 SV=2 6.75 2744 - 504708 - - - 2.7186 - 1.187 0.058 - 63.9 1 2 0 0.0028 9 0 0 0 1.82E+05 1.81E+07 - - - -0.0355 0.9173 230117_WJC_METTL3_WT_vs_EV_F02.11717.11717.2 5.05 12-Jul R.VAGIFPR.L "sp|O96005|CLPT1_HUMAN,tr|K7EJ16|K7EJ16_HUMAN" 2 758.4439 0.8 10244 11717 2 758.446776 380.2292 Cleft lip and palate transmembrane protein 1 OS=Homo sapiens OX=9606 GN=CLPTM1 PE=1 SV=1 9.72 2746 - 368415 - - - 3.7801 - 1.195 0.021 - 111.1 1 2 0 0.0029 7 0 0 0 6.40E+07 8.00E+07 - - - -0.2403 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.11727.11727.2 0.0508 14-Oct R.LGMGLVSR.S "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 831.4637 1.38 10248 11727 2 831.465649 416.7391 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 9.75 2747.2 - 1.66E+06 - - - 2.3946 - 2.316 0.335 - 318.7 1 2 0 0.002 8 0 0 0 6.40E+07 4.63E+07 - - - 4.0476 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.11729.11729.2 0.0243 20-Aug K.LLAETVAPAVR[166.11].G "sp|Q9BSJ8|ESYT1_HUMAN,tr|F8VZB1|F8VZB1_HUMAN" 2 1148.6793 0.001 10250 11729 2 1148.681194 575.3469 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6 2747.5 - 344878 - - - 1.6671 - 1.609 0.335 - 175.1 1 2 0 0.0019 11 0 0 0 0.00E+00 2.15E+07 - - - 2.8014 0.9277 230117_WJC_METTL3_WT_vs_EV_F02.11739.11739.2 2.69 14-Jun R.LVSLIGSK[136.11].T "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 823.5259 1.96 10255 11739 2 823.52748 412.7702 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 2748.8 - 1.12E+06 - - - 1.9744 - 1.05 0.047 - 67.3 5 2 0 0.0016 8 0 0 0 7.71E+07 3.93E+07 - - - -0.7775 0.9919 230117_WJC_METTL3_WT_vs_EV_F02.11744.11744.2 0.0153 18-Jun K.FGEVVDC[160.03]TIK.M "sp|Q99729|ROAA_HUMAN,sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 13 1166.5642 0.77 10258 11744 2 1166.570433 584.2894 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 4.37 2749.4 - 33269.9 - - - 5.3765 - 1.221 0.393 - 94.9 1 2 0 0.0063 10 0 0 0 3.05E+06 3.97E+06 - - - 2.4991 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.11746.11746.2 0.0336 14-Sep R.LLGQIVDR.C sp|Q96I24|FUBP3_HUMAN 1 912.5393 1.48 10259 11746 2 912.541316 457.2769 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2749.7 - 3.27E+07 - - - 2.2465 - 1.787 0.288 - 207.8 1 2 0 0.0021 8 0 0 0 1.16E+09 7.85E+08 - - - 2.9184 1 230117_WJC_METTL3_WT_vs_EV_F02.11754.11754.3 2.75E-07 15/68 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 2.46 10264 11754 3 2070.868165 691.296 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2750.9 - 110785 - - - 0.9045 - 2.894 0.749 - 236.8 1 2 0 0.0019 18 0 0 0 1.14E+07 4.64E+06 - - - 9.5362 0.964 230117_WJC_METTL3_WT_vs_EV_F02.11757.11757.2 1.17 20-Apr K.HFSGLEEAVYR.N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1306.6306 7.7 10265 11757 2 1306.631269 654.3226 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 2751.3 - 157819 - - - 0.512 - 1.113 0.103 - 27.4 7 2 0 0.0007 11 0 0 0 4.33E+06 5.62E+05 - - - -0.2863 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.11761.11761.3 0.000156 13/40 K.HFSGLEEAVYR.N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1306.6306 12.34 10267 11761 3 1306.634657 436.5508 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 2751.7 - 512090 - - - 3.1049 - 2.198 0.386 - 294.5 1 2 0 0.0041 11 0 0 0 1.52E+07 1.23E+06 - - - 5.0797 1 230117_WJC_METTL3_WT_vs_EV_F02.11762.11762.3 2.52E-10 15/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 2.46 10268 11762 3 2078.882645 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2751.9 - 170830 - - - 1.0357 - 3.054 0.697 - 247.7 1 2 0 0.0022 18 0 0 0 1.14E+07 4.64E+06 - - - 9.0903 1 230117_WJC_METTL3_WT_vs_EV_F02.11763.11763.2 8.37E-08 Aug-32 N.IVSNASC[160.03]TTNC[160.03]LAPLAK.V "sp|O14556|G3PT_HUMAN,tr|K7EP73|K7EP73_HUMAN" 2 1818.8968 999 10269 11763 2 1818.904578 910.4557 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 8.06 2752 - 66543.7 - - - 4.2735 - 1.811 0.608 - 115.7 1 1 0 0.0078 17 0 0 0 2.26E+06 0.00E+00 - - - 4.9893 0.97 230117_WJC_METTL3_WT_vs_EV_F02.11779.11779.2 1.4 12-Jun R.SIFDHIK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 866.4742 0.9 10275 11779 2 866.476155 434.2444 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.46 2754.1 - 1.11E+06 - - - 2.3105 - 0.873 0.172 - 95.3 1 2 0 0.002 7 0 0 0 4.39E+07 4.89E+07 - - - -0.1196 0.999 230117_WJC_METTL3_WT_vs_EV_F02.11782.11782.2 0.00494 12-Jul R.VFVVMEK.L "sp|Q15139|KPCD1_HUMAN,sp|O94806|KPCD3_HUMAN,sp|Q9BZL6|KPCD2_HUMAN,tr|M0R2Z8|M0R2Z8_HUMAN,tr|F8WBA3|F8WBA3_HUMAN" 5 850.4623 0.36 10276 11782 2 850.464249 426.2384 Serine\threonine-protein kinase D1 OS=Homo sapiens OX=9606 GN=PRKD1 PE=1 SV=2 5.97 2754.6 - 191734 - - - 2.3376 - 1.404 0.339 - 111.8 1 2 0 0.002 7 0 0 0 1.51E+07 4.16E+07 - - - 2.6194 0.9908 230117_WJC_METTL3_WT_vs_EV_F02.11786.11786.2 0.213 16-May K.ESYSVYVYK[136.11].V "sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 10 1144.5532 1.38 10278 11786 2 1144.556288 573.2839 Histone H2B type 2-F OS=Homo sapiens OX=9606 GN=H2BC18 PE=1 SV=3 6.1 2755 - 56578.1 - - - 2.7059 - 0.993 0.247 - 80.8 1 2 0 0.0031 9 0 0 0 7.36E+06 5.32E+06 - - - 0.844 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.11790.11790.2 0.00351 14-Jul R.ILDAPEIR[166.11].N sp|Q12834|CDC20_HUMAN 1 935.5316 1.84 10279 11790 2 935.533963 468.7731 Cell division cycle protein 20 homolog OS=Homo sapiens OX=9606 GN=CDC20 PE=1 SV=2 4.37 2755.6 - 317882 - - - 2.5771 - 1.655 0.291 - 128.4 1 2 0 0.0024 8 0 0 0 1.96E+07 1.07E+07 - - - 2.709 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.11798.11798.2 0.0101 24-Aug R.SILSPGGSC[160.03]GPIK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1279.6686 0.92 10283 11798 2 1279.668869 640.8416 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 7.94 2756.6 - 112080 - - - 0.2313 - 1.644 0.309 - 117.4 1 2 0 0.0003 13 0 0 0 4.42E+06 4.81E+06 - - - 2.5991 0.9911 230117_WJC_METTL3_WT_vs_EV_F02.11799.11799.2 0.498 20-Jul R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 1.24 10284 11799 2 1166.706079 584.3584 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2756.7 - 105583 - - - 3.2313 - 1.349 0.17 - 121.8 1 2 0 0.0038 11 0 0 0 6.19E+07 4.98E+07 - - - 1.1053 0.9704 230117_WJC_METTL3_WT_vs_EV_F02.11804.11804.2 0.013 12-Jul K.LDPVLYR.K "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 874.4913 0.93 10287 11804 2 874.49346 438.2529 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 5.84 2757.3 - 798242 - - - 2.5238 - 1.275 0.02 - 220 1 2 0 0.0022 7 0 0 0 1.25E+08 1.34E+08 - - - -0.0422 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.11807.11807.2 0.439 16-Sep K.VGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 911.5804 2.02 10288 11807 2 911.582526 456.7975 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2757.7 - 2.50E+06 - - - 2.3289 - 1.899 0.223 - 202.2 1 2 0 0.0021 9 0 0 0 7.49E+08 3.70E+08 - - - 2.5428 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.11808.11808.2 0.023 16-Nov K.VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 919.5946 2.02 10289 11808 2 919.596399 460.8046 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2757.8 - 1.79E+06 - - - 1.953 - 2.305 0.252 - 313.8 1 2 0 0.0018 9 0 0 0 7.49E+08 3.70E+08 - - - 3.3176 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.11812.11812.2 0.000836 18-Sep K.YEELQVTVGR.H sp|P35908|K22E_HUMAN 1 1192.6088 18.66 10291 11812 2 1192.613811 597.3117 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.53 2758.3 - 132642 - - - 4.2 - 1.68 0.353 - 274.8 1 2 0 0.005 10 0 0 0 2.89E+06 1.55E+05 - - - 3.0948 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.11814.11814.3 0.0929 16/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 0.78 10292 11814 3 1166.70533 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2758.6 - 2.80E+06 - - - 2.5893 - 2.618 0.264 - 246.9 1 2 0 0.003 11 0 0 0 3.06E+08 3.91E+08 - - - 4.2165 0.9178 230117_WJC_METTL3_WT_vs_EV_F02.11816.11816.2 0.0383 16-Aug L.ASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 940.5342 1.09 10294 11816 2 940.537362 471.2744 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 2758.8 - 271791 - - - 3.3821 - 1.67 0.372 - 180.9 1 1 0 0.0032 9 0 0 0 2.16E+07 1.98E+07 - - - 3.2712 0.9048 230117_WJC_METTL3_WT_vs_EV_F02.11817.11817.2 0.16 18-Sep L.LASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1053.6182 0.74 10295 11817 2 1053.621496 527.8164 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2759 - 191541 - - - 3.0856 - 1.583 0.337 - 211.6 1 1 0 0.0033 10 0 0 0 1.16E+07 1.55E+07 - - - 2.8112 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.11825.11825.3 0.000365 15/40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 0.78 10299 11825 3 1174.71832 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2759.9 - 6.18E+06 - - - 1.5416 - 2.784 0.275 - 209 1 2 0 0.0018 11 0 0 0 3.05E+08 3.90E+08 - - - 4.5142 0.9876 230117_WJC_METTL3_WT_vs_EV_F02.11826.11826.2 0.112 12-Jun K.LDPVLYR[166.11].K "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 884.4995 0.93 10300 11826 2 884.501046 443.257 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 5.84 2760 - 2.63E+06 - - - 1.7219 - 1.155 0.115 - 182.9 1 2 0 0.0015 7 0 0 0 1.25E+08 1.34E+08 - - - 0.3465 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.11827.11827.2 1.41 12-Sep K.LEDLIVK[136.11].D "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 836.5099 2 10301 11827 2 836.510387 419.2622 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2760.1 - 1.71E+06 - - - 0.618 - 2.067 0.12 - 220.9 1 2 0 0.0005 7 0 0 0 1.43E+09 7.15E+08 - - - 2.2278 0.998 230117_WJC_METTL3_WT_vs_EV_F02.11852.11852.2 2.29 12-Aug R.LGLTEIR[166.11].K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 810.4839 1.17 10310 11852 2 810.484672 406.2492 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2763.5 - 1.16E+06 - - - 0.9858 - 1.731 0.129 - 193.7 1 2 0 0.0008 7 0 0 0 1.05E+09 8.96E+08 - - - 1.7321 0.8932 230117_WJC_METTL3_WT_vs_EV_F02.11854.11854.2 6.44 12-May R.NLGLYVK.T "sp|Q14697|GANAB_HUMAN,tr|E9PKU7|E9PKU7_HUMAN,tr|F5H6X6|F5H6X6_HUMAN" 3 805.4698 0.21 10312 11854 2 805.470793 403.7422 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 8.59 2763.7 - 614979 - - - 1.2452 - 0.994 0.002 - 74.3 2 2 0 0.001 7 0 0 0 2.01E+07 9.51E+07 - - - -1.0981 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.11857.11857.2 1.18 12-Aug K.LEDLIVK.D "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 828.4957 2 10314 11857 2 828.496698 415.2551 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2764 - 1.59E+07 - - - 1.2408 - 1.87 0.065 - 203.6 1 2 0 0.001 7 0 0 0 1.42E+09 7.12E+08 - - - 1.5041 0.9928 230117_WJC_METTL3_WT_vs_EV_F02.11868.11868.2 1.51 12-Jun K.FLEATLR.S "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN" 2 848.4756 0.78 10317 11868 2 848.475562 425.2451 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 6 2765.7 - 530575 - - - -0.0483 - 1.371 0.132 - 121.3 1 2 0 0 7 0 0 0 3.78E+07 4.84E+07 - - - 1.0157 0.9907 230117_WJC_METTL3_WT_vs_EV_F02.11869.11869.2 2.11 12-May R.LGLTEIR.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 800.4756 1.17 10318 11869 2 800.476248 401.2451 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2765.8 - 4.12E+06 - - - 0.8058 - 1.419 0.085 - 75.9 3 2 0 0.0006 7 0 0 0 1.05E+09 8.97E+08 - - - 0.5643 0.9887 230117_WJC_METTL3_WT_vs_EV_F02.11873.11873.2 0.374 12-Jun K.FLEATLR[166.11].S "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN" 2 858.4839 0.78 10319 11873 2 858.486267 430.2492 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 6 2766.4 - 765966 - - - 2.7886 - 1.176 0.158 - 118.6 1 2 0 0.0024 7 0 0 0 3.77E+07 4.84E+07 - - - 0.7209 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.11878.11878.2 0.0123 18-Jul K.LITPAVVSER[166.11].L sp|P62851|RS25_HUMAN 1 1093.6371 1.07 10322 11878 2 1093.639797 547.8258 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 6 2766.9 - 188938 - - - 2.4853 - 1.444 0.317 - 142 1 2 0 0.0027 10 0 0 0 1.17E+07 1.09E+07 - - - 2.4071 0.9919 230117_WJC_METTL3_WT_vs_EV_F02.11905.11905.2 0.459 14-Aug K.LIEQYALR.E sp|Q9NUQ3|TXLNG_HUMAN 1 1004.5655 1.53 10331 11905 2 1004.565551 503.29 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2770.6 - 273851 - - - 0.0697 - 1.11 0.206 - 181.7 1 2 0 0.0001 8 0 0 0 4.11E+07 2.68E+07 - - - 0.8772 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.11915.11915.2 1.67 14-Aug K.LIEQYALR[166.11].E sp|Q9NUQ3|TXLNG_HUMAN 1 1014.5738 1.53 10335 11915 2 1014.575401 508.2942 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2772 - 312017 - - - 1.6263 - 1.465 0.168 - 178.4 1 2 0 0.0016 8 0 0 0 4.11E+07 2.68E+07 - - - 1.433 0.9746 230117_WJC_METTL3_WT_vs_EV_F02.11921.11921.2 0.105 12-May K.LMPTQWR.T sp|Q99459|CDC5L_HUMAN 1 930.4746 1.14 10338 11921 2 930.475388 466.2446 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.75 2772.8 - 291669 - - - 0.8931 - 1.054 0.119 - 90.2 3 2 0 0.0008 7 0 0 0 4.51E+07 3.95E+07 - - - -0.1268 0.9191 230117_WJC_METTL3_WT_vs_EV_F02.11929.11929.2 2.4 12-Jun K.LMPTQWR[166.11].T sp|Q99459|CDC5L_HUMAN 1 940.4828 1.14 10340 11929 2 940.485357 471.2487 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.75 2774 - 1.02E+06 - - - 2.6901 - 1.009 0.038 - 160.1 1 2 0 0.0025 7 0 0 0 4.52E+07 3.96E+07 - - - -0.6507 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.11930.11930.2 0.233 12-Aug R.IGNFIVK.K "sp|Q00796|DHSO_HUMAN,tr|H0YKB3|H0YKB3_HUMAN,tr|A0A6I8PIS1|A0A6I8PIS1_HUMAN" 3 789.4749 25.03 10341 11930 2 789.476374 395.7447 Sorbitol dehydrogenase OS=Homo sapiens OX=9606 GN=SORD PE=1 SV=4 8.75 2774.1 - 616887 - - - 1.8987 - 1.537 0.161 - 135.6 1 2 0 0.0015 7 0 0 0 3.36E+07 1.34E+06 - - - 1.5916 0.9801 230117_WJC_METTL3_WT_vs_EV_F02.11963.11963.2 0.178 12-Jul K.FAISLPK.A "sp|Q9BXM0|PRAX_HUMAN,tr|A0A669KBF1|A0A669KBF1_HUMAN,tr|A0A6Q8PGB6|A0A6Q8PGB6_HUMAN" 3 774.464 0.95 10353 11963 2 774.464706 388.2393 Periaxin OS=Homo sapiens OX=9606 GN=PRX PE=1 SV=2 8.75 2778.6 - 475200 - - - 0.9426 - 1.391 0.01 - 157.8 2 2 0 0.0007 7 0 0 0 6.61E+07 6.99E+07 - - - 0.0259 0.9965 230117_WJC_METTL3_WT_vs_EV_F02.11970.11970.2 0.169 16-Aug R.LITGLGVGR[166.11].E sp|Q9BQG0|MBB1A_HUMAN 1 894.5526 1.27 10354 11970 2 894.552869 448.2836 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 9.75 2779.7 - 427663 - - - 0.2772 - 1.261 0.236 - 137.2 1 2 0 0.0002 9 0 0 0 1.60E+08 1.26E+08 - - - 1.4549 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.11977.11977.2 0.0906 24-Nov R.GGIGAGLGGGLC[160.03]R[166.11].R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1153.5901 0.57 10358 11977 2 1153.591282 577.8023 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2780.5 - 371660 - - - 0.9848 - 1.811 0.304 - 273.3 1 2 0 0.0011 13 0 0 0 1.04E+07 1.82E+07 - - - 2.8102 0.9744 230117_WJC_METTL3_WT_vs_EV_F02.11982.11982.2 1.24 12-Jul K.FVNLYTR.E "sp|Q15650|TRIP4_HUMAN,tr|H0YL91|H0YL91_HUMAN" 2 911.4865 1.71 10360 11982 2 911.485365 456.7505 Activating signal cointegrator 1 OS=Homo sapiens OX=9606 GN=TRIP4 PE=1 SV=4 8.75 2781.1 - 247683 - - - -1.2474 - 1.227 0.125 - 129.1 1 2 0 -0.0011 7 0 0 0 2.39E+07 1.40E+07 - - - 0.6121 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.11983.11983.2 0.0209 24-Aug R.GGIGAGLGGGLC[160.03]R.R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1143.5819 0.57 10361 11983 2 1143.583273 572.7982 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2781.3 - 142030 - - - 1.2216 - 1.503 0.249 - 132.2 1 2 0 0.0014 13 0 0 0 1.04E+07 1.82E+07 - - - 1.9254 0.9881 230117_WJC_METTL3_WT_vs_EV_F02.11997.11997.2 1.2 12-May R.FALVTPK[136.11].K sp|P49792|RBP2_HUMAN 1 782.4782 1.16 10368 11997 2 782.478576 392.2464 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.75 2783.1 - 827040 - - - 0.5112 - 1.171 0.142 - 61.5 2 2 0 0.0004 7 0 0 0 6.44E+07 5.53E+07 - - - 0.4554 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.12001.12001.2 0.00252 20-Nov K.LATNAAVTVLR.V "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1127.6663 167.04 10370 12001 2 1127.663381 564.8404 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 9.75 2783.6 - 214261 - - - -2.5513 - 2.175 0.354 - 403.4 1 2 0 -0.0029 11 0 0 0 8.76E+06 5.24E+04 - - - 3.7568 0.9705 230117_WJC_METTL3_WT_vs_EV_F02.12006.12006.2 0.0394 12-Jul R.AAYIYIR[166.11].G "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|B4DE93|B4DE93_HUMAN,tr|E9PJL9|E9PJL9_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PLC6|E9PLC6_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN" 8 878.489 3.36 10372 12006 2 878.485364 440.2518 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.63 2784.2 - 210336 - - - -4.0923 - 1.372 0.255 - 173 1 2 0 -0.0036 7 0 0 0 8.47E+07 2.52E+07 - - - 1.9254 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.12009.12009.2 0.0202 14-Jul K.ILVDALQK.F "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 15 898.5488 1.04 10373 12009 2 898.550128 450.2817 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 5.84 2784.6 - 559752 - - - 1.5136 - 1.525 0.208 - 97 1 2 0 0.0014 8 0 0 0 5.95E+07 5.71E+07 - - - 1.8496 0.9939 230117_WJC_METTL3_WT_vs_EV_F02.12018.12018.2 0.662 12-Jul K.ILLVDER.S "sp|A5YKK6|CNOT1_HUMAN,tr|H3BMZ2|H3BMZ2_HUMAN" 2 856.5018 1.12 10376 12018 2 856.504019 429.2582 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.37 2785.8 - 1.33E+06 - - - 2.5698 - 1.438 0.123 - 175.7 1 2 0 0.0022 7 0 0 0 7.14E+07 6.36E+07 - - - 1.0998 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.12034.12034.2 0.201 14-Oct R.ALLGPALK.D sp|P35250|RFC2_HUMAN 1 781.5062 1.92 10383 12034 2 781.506022 391.7604 Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3 8.8 2787.9 - 1.58E+06 - - - -0.1958 - 1.656 0.242 - 303.8 1 2 0 -0.0002 8 0 0 0 9.70E+07 5.06E+07 - - - 2.3496 0.997 230117_WJC_METTL3_WT_vs_EV_F02.12035.12035.2 0.59 12-Jul K.ILLVDER[166.11].S "sp|A5YKK6|CNOT1_HUMAN,tr|H3BMZ2|H3BMZ2_HUMAN" 2 866.5101 1.14 10384 12035 2 866.5091 434.2623 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.37 2787.9 - 1.72E+06 - - - -1.1402 - 1.519 0.27 - 184 1 2 0 -0.001 7 0 0 0 7.14E+07 6.27E+07 - - - 2.3595 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.12043.12043.2 0.597 12-Aug K.LTELLVK[136.11].A "sp|O95470|SGPL1_HUMAN,tr|H0Y3V8|H0Y3V8_HUMAN,tr|H7BXL7|H7BXL7_HUMAN" 3 822.5306 2.47 10387 12043 2 822.531539 412.2726 Sphingosine-1-phosphate lyase 1 OS=Homo sapiens OX=9606 GN=SGPL1 PE=1 SV=3 6 2789.1 - 566956 - - - 1.1355 - 1.498 0.237 - 166.6 1 2 0 0.0009 7 0 0 0 6.60E+07 2.68E+07 - - - 2.0717 0.9928 230117_WJC_METTL3_WT_vs_EV_F02.12050.12050.2 0.262 14-Aug K.ILVDALQK[136.11].F "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 15 906.563 1.06 10390 12050 2 906.564312 454.2888 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 5.84 2789.9 - 1.32E+06 - - - 1.4825 - 1.434 0.079 - 175.8 1 2 0 0.0013 8 0 0 0 6.05E+07 5.72E+07 - - - 0.7112 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.12055.12055.2 0.015 12-Aug K.VPVNLLR[166.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 819.5206 1.16 10393 12055 2 819.520539 410.7676 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2790.6 - 682311 - - - -0.0659 - 1.551 0.318 - 342.5 1 2 0 -0.0001 7 0 0 0 1.44E+08 1.25E+08 - - - 2.7804 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.12058.12058.2 0.773 12-Aug K.LTELLVK.A "sp|O95470|SGPL1_HUMAN,tr|H0Y3V8|H0Y3V8_HUMAN,tr|H7BXL7|H7BXL7_HUMAN" 3 814.5164 2.01 10395 12058 2 814.515509 408.2655 Sphingosine-1-phosphate lyase 1 OS=Homo sapiens OX=9606 GN=SGPL1 PE=1 SV=3 6 2790.9 - 853456 - - - -1.1 - 1.553 0.248 - 158.8 1 2 0 -0.0009 7 0 0 0 7.44E+07 3.71E+07 - - - 2.2672 1 230117_WJC_METTL3_WT_vs_EV_F02.12063.12063.2 0.00483 13/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 10398 12063 2 1302.610234 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2791.5 - 1.93E+06 - - - 0.7969 - 2.33 0.524 - 353.3 1 2 0 0.001 13 0 0 0 1.61E+09 0.00E+00 - - - 5.0819 0.9956 230117_WJC_METTL3_WT_vs_EV_F02.12064.12064.2 0.125 12-Jul K.VPVNLLR.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 809.5123 1.16 10399 12064 2 809.51232 405.7634 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2791.7 - 1.31E+06 - - - -0.0037 - 1.263 0.216 - 233.4 1 2 0 0 7 0 0 0 1.44E+08 1.25E+08 - - - 1.3762 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.12066.12066.2 0.264 18-Aug K.QLVTNAC[160.03]LIK[136.11].E "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 3 1166.6573 0.2 10401 12066 2 1166.658235 584.3359 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 8.22 2791.9 - 178007 - - - 0.8186 - 1.568 0.115 - 168.6 1 2 0 0.001 10 0 0 0 8.69E+05 4.28E+06 - - - 1.1456 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.12076.12076.2 1.45E-05 20-Nov R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 9785.23 10407 12076 2 1201.60983 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2793.1 - 852731 - - - 0.5767 - 2.04 0.476 - 184.5 1 2 0 0.0007 11 0 0 0 6.81E+09 6.96E+05 - - - 4.4852 0.9969 230117_WJC_METTL3_WT_vs_EV_F02.12086.12086.2 0.0709 12-Jul K.IDPLLPK.E sp|Q9BYD6|RM01_HUMAN 1 794.4902 2.62 10412 12086 2 794.489775 398.2524 "39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2" 5.84 2794.4 - 1.94E+06 - - - -0.5236 - 1.397 0.251 - 138.1 1 2 0 -0.0004 7 0 0 0 2.49E+08 9.52E+07 - - - 1.9541 0.9691 230117_WJC_METTL3_WT_vs_EV_F02.12087.12087.2 0.418 12-Jul K.IDPLLPK[136.11].E sp|Q9BYD6|RM01_HUMAN 1 802.5044 2.6 10413 12087 2 802.503487 402.2595 "39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2" 5.84 2794.4 - 1.68E+06 - - - -1.1265 - 1.088 0.151 - 102.5 1 2 0 -0.0009 7 0 0 0 2.47E+08 9.52E+07 - - - 0.4232 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.12097.12097.2 0.00143 12-Sep R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.98 10415 12097 2 852.482561 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2796.1 - 1.37E+07 - - - -1.2833 - 1.415 0.361 - 228.9 1 2 0 -0.0011 7 0 0 0 1.66E+09 8.37E+08 - - - 2.8069 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.12116.12116.2 0.000367 12-Aug R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.37 10423 12116 2 844.469164 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2798.6 - 1.67E+07 - - - -0.3446 - 1.597 0.326 - 175.9 1 2 0 -0.0003 7 0 0 0 1.14E+10 8.35E+09 - - - 2.932 0.9879 230117_WJC_METTL3_WT_vs_EV_F02.12120.12120.3 1.05 Oct-40 R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 505.04 10426 12120 3 1201.609144 401.5437 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2799 - 2.36E+06 - - - 0.0058 - 1.512 0.168 - 114.2 1 2 0 0 11 0 0 0 4.19E+08 8.30E+05 - - - 1.5875 0.9017 230117_WJC_METTL3_WT_vs_EV_F02.12124.12124.2 0.00825 14-Aug R.LLASTLVH.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 852.5069 - 10428 12124 2 852.506365 427.2607 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.74 2799.5 - 1.75E+07 - - - -0.6311 - 1.554 0.342 - 193.3 1 1 0 -0.0005 8 0 0 0 - - - - - 2.8964 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.12125.12125.2 1.48 14-Jun K.ILFTEATR.L "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 949.5233 1.73 10429 12125 2 949.523581 475.7689 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 6 2799.6 - 1.27E+06 - - - 0.3149 - 1.29 0.271 - 100.9 1 2 0 0.0003 8 0 0 0 4.19E+07 2.42E+07 - - - 1.8105 0.9463 230117_WJC_METTL3_WT_vs_EV_F02.12129.12129.4 0.33 13/96 T.LLLIILTDVFIISTVLR.L sp|Q8NGY0|O10X1_HUMAN 1 1941.2278 999 10431 12129 4 1941.232628 486.3142 Olfactory receptor 10X1 OS=Homo sapiens OX=9606 GN=OR10X1 PE=3 SV=2 5.84 2800.1 - 581227 - - - 2.4758 - 1.917 0.26 - 84.2 1 1 0 0.0048 17 0 0 0 2.09E+07 0.00E+00 - - - 1.7137 0.9871 230117_WJC_METTL3_WT_vs_EV_F02.12133.12133.2 0.00108 14-Sep R.TFGVSPLR.R sp|Q5T750|XP32_HUMAN 1 875.4865 23.24 10435 12133 2 875.492375 438.7505 Skin-specific protein 32 OS=Homo sapiens OX=9606 GN=XP32 PE=1 SV=1 9.41 2800.6 - 383184 - - - 6.7083 - 1.516 0.364 - 168.1 1 2 0 0.0059 8 0 0 0 8.77E+07 3.77E+06 - - - 2.9825 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.12155.12155.2 0.0436 16-Jun K.LVPVGYGIK[136.11].K sp|P24534|EF1B_HUMAN 1 952.5837 0.73 10441 12155 2 952.58367 477.2991 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2803.8 - 753985 - - - -0.0357 - 1.344 0.373 - 88.9 1 2 0 0 9 0 0 0 1.36E+09 1.86E+09 - - - 2.6513 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.12156.12156.2 0.0702 12-Aug K.MLEYALK.Q "sp|Q13033|STRN3_HUMAN,sp|Q9NRL3|STRN4_HUMAN,sp|O43815|STRN_HUMAN,tr|M0R0P4|M0R0P4_HUMAN,tr|G3V3G7|G3V3G7_HUMAN,tr|F5GYK2|F5GYK2_HUMAN,tr|M0R2A7|M0R2A7_HUMAN,tr|M0QYS2|M0QYS2_HUMAN,tr|M0R0W8|M0R0W8_HUMAN,tr|G3V340|G3V340_HUMAN,tr|M0QXN2|M0QXN2_HUMAN" 11 866.4572 4.6 10442 12156 2 866.456412 434.2359 Striatin-3 OS=Homo sapiens OX=9606 GN=STRN3 PE=1 SV=3 5.75 2803.9 - 1.17E+06 - - - -0.8818 - 1.453 0.314 - 223 1 2 0 -0.0008 7 0 0 0 4.78E+07 1.04E+07 - - - 2.5438 0.995 230117_WJC_METTL3_WT_vs_EV_F02.12163.12163.2 0.393 14-Jul R.LLEEGVLR.Q "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 927.5389 2.03 10446 12163 2 927.538389 464.7767 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 2804.7 - 434235 - - - -0.5854 - 1.338 0.222 - 140.9 1 2 0 -0.0005 8 0 0 0 1.32E+08 6.48E+07 - - - 1.5587 0.9546 230117_WJC_METTL3_WT_vs_EV_F02.12169.12169.2 0.387 12-Jul R.ILLYAC[160.03]R.N "sp|P36954|RPB9_HUMAN,tr|K7EKS1|K7EKS1_HUMAN" 2 907.495 1.27 10449 12169 2 907.49319 454.7548 DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1 8.22 2805.6 - 368589 - - - -1.9493 - 1.349 0.071 - 156.2 1 2 0 -0.0018 7 0 0 0 9.91E+07 7.80E+07 - - - 0.5134 0.999 230117_WJC_METTL3_WT_vs_EV_F02.12174.12174.2 0.0234 16-Sep K.LVPVGYGIK.K sp|P24534|EF1B_HUMAN 1 944.5695 0.73 10451 12174 2 944.569155 473.292 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2806.2 - 3.20E+06 - - - -0.3695 - 1.771 0.329 - 316.8 1 2 0 -0.0003 9 0 0 0 1.36E+09 1.86E+09 - - - 3.1244 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.12181.12181.2 0.0337 16-Sep R.NVIEAVYSR[166.11].L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1059.5588 1.44 10455 12181 2 1059.558997 530.7867 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 2807.1 - 337598 - - - 0.1586 - 1.605 0.274 - 241.7 1 2 0 0.0002 9 0 0 0 7.63E+07 5.31E+07 - - - 2.4335 0.9665 230117_WJC_METTL3_WT_vs_EV_F02.12184.12184.2 3.55 12-Jul K.IPVIIER.Y "sp|A6NCE7|MP3B2_HUMAN,sp|Q9GZQ8|MLP3B_HUMAN,sp|Q9H492|MLP3A_HUMAN,tr|H3BTL1|H3BTL1_HUMAN" 4 838.5276 1.32 10456 12184 2 838.526039 420.2711 Microtubule-associated proteins 1A\1B light chain 3 beta 2 OS=Homo sapiens OX=9606 GN=MAP1LC3B2 PE=2 SV=1 6 2807.4 - 874902 - - - -1.9081 - 1.399 0.083 - 193.1 1 2 0 -0.0016 7 0 0 0 4.75E+07 3.60E+07 - - - 0.7174 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.12203.12203.2 0.144 14-Aug R.VFVSPLAK.K "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 859.5167 0.76 10461 12203 2 859.518621 430.7656 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 8.72 2810.2 - 5.83E+06 - - - 2.1884 - 1.401 0.285 - 224.3 1 2 0 0.0019 8 0 0 0 3.35E+08 4.39E+08 - - - 2.1624 0.9908 230117_WJC_METTL3_WT_vs_EV_F02.12223.12223.2 0.00205 12-Jul K.LSIVPVR[166.11].R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 792.5097 0.86 10467 12223 2 792.50851 397.2621 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2813 - 3.13E+07 - - - -1.494 - 1.503 0.163 - 167.3 1 2 0 -0.0012 7 0 0 0 2.82E+09 3.28E+09 - - - 1.5356 1 230117_WJC_METTL3_WT_vs_EV_F02.12229.12229.2 5.71E-06 20-Dec R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 250.28 10469 12229 2 1264.629597 633.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2813.7 - 869403 - - - -0.2649 - 2.415 0.52 - 296.5 1 2 0 -0.0003 11 0 0 0 2.53E+07 1.01E+05 - - - 5.2668 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.12247.12247.2 0.225 14-Jul K.TPVIVTLK[136.11].E "sp|Q9Y4L1|HYOU1_HUMAN,tr|A0A087WWI4|A0A087WWI4_HUMAN,tr|K7EQK2|K7EQK2_HUMAN,tr|A0A087WW13|A0A087WW13_HUMAN,tr|Q9BST8|Q9BST8_HUMAN,tr|J3KTF1|J3KTF1_HUMAN,tr|A0A494C039|A0A494C039_HUMAN,tr|J3QL06|J3QL06_HUMAN,tr|A0A087X214|A0A087X214_HUMAN,tr|A0A087X054|A0A087X054_HUMAN,tr|E9PJ21|E9PJ21_HUMAN,tr|J3QLE9|J3QLE9_HUMAN,tr|J3QQH7|J3QQH7_HUMAN" 13 877.5728 0.99 10474 12247 2 877.57423 439.7937 Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1 8.41 2816.4 - 371767 - - - 1.6238 - 1.458 0.245 - 105.9 1 2 0 0.0014 8 0 0 0 1.15E+07 1.17E+07 - - - 1.9873 0.9963 230117_WJC_METTL3_WT_vs_EV_F02.12258.12258.2 0.188 12-Jul K.LSIVPVR.R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 782.5014 0.86 10475 12258 2 782.501405 392.258 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2818.1 - 6.29E+07 - - - -0.0243 - 1.495 0.166 - 183.9 1 2 0 0 7 0 0 0 2.82E+09 3.28E+09 - - - 1.5412 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.12260.12260.2 0.00162 14-Aug R.VFVSPLAK[136.11].K "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 867.5309 0.76 10476 12260 2 867.530296 434.7727 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 8.72 2818.4 - 1.58E+06 - - - -0.7423 - 1.642 0.479 - 210.7 1 2 0 -0.0006 8 0 0 0 3.35E+08 4.39E+08 - - - 4.0743 0.9932 230117_WJC_METTL3_WT_vs_EV_F02.12264.12264.2 0.107 14-Aug R.MVDFAGVK.D "sp|P21964|COMT_HUMAN,tr|E7EUU8|E7EUU8_HUMAN,tr|E7EMS6|E7EMS6_HUMAN,tr|F8WBW9|F8WBW9_HUMAN,tr|H7BZ45|H7BZ45_HUMAN,tr|A0A7I2V3G7|A0A7I2V3G7_HUMAN,tr|A0A7I2V370|A0A7I2V370_HUMAN" 7 865.4368 1.27 10477 12264 2 865.435726 433.7257 Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT PE=1 SV=2 5.59 2818.9 - 1.36E+06 - - - -1.2121 - 1.13 0.302 - 119.4 1 2 0 -0.001 8 0 0 0 1.08E+08 8.47E+07 - - - 1.6398 0.9957 230117_WJC_METTL3_WT_vs_EV_F02.12270.12270.2 0.237 16-Jun K.VLEGMEVVR[166.11].K "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1040.5564 0.14 10478 12270 2 1040.557775 521.2855 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.53 2819.9 - 224714 - - - 1.3349 - 1.291 0.195 - 101.5 2 2 0 0.0014 9 0 0 0 8.58E+06 6.01E+07 - - - 1.0853 0.9827 230117_WJC_METTL3_WT_vs_EV_F02.12281.12281.2 8.57 12-Jul K.IILQTIK.W "sp|Q5VT40|FA78B_HUMAN,sp|O75909|CCNK_HUMAN,tr|H7C075|H7C075_HUMAN,tr|H7C3M6|H7C3M6_HUMAN,tr|G3V2Q3|G3V2Q3_HUMAN,tr|G3V5E1|G3V5E1_HUMAN" 6 827.548 0.95 10484 12281 2 827.549529 414.7813 Protein FAM78B OS=Homo sapiens OX=9606 GN=FAM78B PE=2 SV=1 8.75 2821.2 - 587657 - - - 1.7993 - 1.282 0.041 - 99 1 2 0 0.0015 7 0 0 0 1.36E+07 1.43E+07 - - - 0.1305 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.12304.12304.2 0.185 12-Jun K.YLYEIAR.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 926.4862 47.26 10497 12304 2 926.486548 464.2504 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6 2824 - 1.39E+07 - - - 0.4102 - 1.224 0.254 - 124.2 1 2 0 0.0004 7 0 0 0 8.12E+08 1.72E+07 - - - 1.5574 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.12321.12321.2 0.00242 12-Aug R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.3 10503 12321 2 852.484192 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2826.4 - 5.73E+07 - - - 0.6299 - 1.53 0.299 - 198.5 1 2 0 0.0005 7 0 0 0 9.76E+09 7.51E+09 - - - 2.5967 0.9702 230117_WJC_METTL3_WT_vs_EV_F02.12327.12327.2 2.55 12-Jul K.GVTLGFR[166.11].Y "sp|P32969|RL9_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 4 758.4314 0.001 10506 12327 2 758.432715 380.223 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 9.75 2827 - 1.66E+06 - - - 1.6758 - 1.29 0.006 - 234 2 2 0 0.0013 7 0 0 0 0.00E+00 9.99E+07 - - - -0.2427 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.12329.12329.2 0.715 14-Aug K.IIGDTFVK.L sp|P49915|GUAA_HUMAN 1 891.5066 2.55 10507 12329 2 891.507644 446.7606 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.84 2827.2 - 1.75E+06 - - - 1.2058 - 1.553 0.176 - 141.7 1 2 0 0.0011 8 0 0 0 3.08E+08 1.21E+08 - - - 1.6682 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.12342.12342.2 0.0018 12-Aug R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.37 10513 12342 2 844.471184 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2828.7 - 5.15E+07 - - - 2.0474 - 1.587 0.301 - 198.7 1 2 0 0.0017 7 0 0 0 1.14E+10 8.35E+09 - - - 2.727 0.9951 230117_WJC_METTL3_WT_vs_EV_F02.12347.12347.2 1.43 14-Jul R.ITPELLTR.G sp|P19367|HXK1_HUMAN 1 941.5546 1.97 10516 12347 2 941.556008 471.7846 Hexokinase-1 OS=Homo sapiens OX=9606 GN=HK1 PE=1 SV=3 6 2829.3 - 301380 - - - 1.5145 - 1.269 0.166 - 130.6 1 2 0 0.0014 8 0 0 0 1.21E+07 6.13E+06 - - - 0.9851 0.9969 230117_WJC_METTL3_WT_vs_EV_F02.12387.12387.2 0.232 14-Jun R.LADIVVPR.G sp|Q9NWZ5|UCKL1_HUMAN 1 881.5335 3.88 10534 12387 2 881.535499 441.774 Uridine-cytidine kinase-like 1 OS=Homo sapiens OX=9606 GN=UCKL1 PE=1 SV=2 5.84 2834.6 - 313738 - - - 2.3221 - 1.499 0.192 - 84.8 2 2 0 0.002 8 0 0 0 1.86E+07 4.78E+06 - - - 1.5449 0.8574 230117_WJC_METTL3_WT_vs_EV_F02.12403.12403.2 0.529 16-Aug E.VDELPSLMK.L "sp|Q9UHL0|DDX25_HUMAN,tr|E9PR46|E9PR46_HUMAN,tr|J3QL17|J3QL17_HUMAN,tr|J3QRJ6|J3QRJ6_HUMAN" 4 1030.5369 5.55 10543 12403 2 1030.536326 516.2757 ATP-dependent RNA helicase DDX25 OS=Homo sapiens OX=9606 GN=DDX25 PE=1 SV=2 4.37 2836.6 - 1.58E+06 - - - -0.5405 - 1.852 0.207 - 186.6 1 1 0 -0.0006 9 0 0 0 1.33E+08 2.40E+07 - - - 2.3526 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.12406.12406.2 0.0214 20-May R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 114.71 10544 12406 2 1201.611467 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2837 - 197443 - - - 1.9391 - 1.485 0.336 - 33.6 24 2 0 0.0023 11 0 0 0 1.18E+07 1.03E+05 - - - 1.9751 0.9944 230117_WJC_METTL3_WT_vs_EV_F02.12422.12422.2 1.72 12-Jul R.LLSVNIR.V sp|P07814|SYEP_HUMAN 1 813.5072 1.43 10551 12422 2 813.507651 407.7609 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 9.75 2839 - 1.04E+06 - - - 0.5077 - 1.31 0.15 - 128.9 1 2 0 0.0004 7 0 0 0 2.60E+08 1.82E+08 - - - 1.0044 0.9603 230117_WJC_METTL3_WT_vs_EV_F02.12428.12428.2 15.8 12-Jun K.LLIQVER[166.11].S sp|Q96RL7|VP13A_HUMAN 1 879.5417 1.15 10555 12428 2 879.543471 440.7781 Vacuolar protein sorting-associated protein 13A OS=Homo sapiens OX=9606 GN=VPS13A PE=1 SV=2 6 2839.7 - 497819 - - - 1.9885 - 1.252 0 - 103.7 2 2 0 0.0017 7 0 0 0 2.96E+07 2.57E+07 - - - -0.3819 0.95 230117_WJC_METTL3_WT_vs_EV_F02.12431.12431.2 0.00608 16-Sep R.PLISVYSEK.G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1034.5648 0.8 10556 12431 2 1034.567699 518.2897 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.42 2840.1 - 1.05E+06 - - - 2.7905 - 1.665 0.408 - 299.7 1 1 0 0.0029 9 0 0 0 4.87E+07 6.11E+07 - - - 3.5285 0.9969 230117_WJC_METTL3_WT_vs_EV_F02.12433.12433.2 0.321 14-Jul K.LIGEYGLR.N "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 919.5127 0.8 10557 12433 2 919.513554 460.7636 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 2840.4 - 1.52E+06 - - - 0.9103 - 1.411 0.176 - 111.8 1 2 0 0.0008 8 0 0 0 2.31E+09 2.89E+09 - - - 1.3791 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.12468.12468.2 0.00519 18-Oct K.DVNAAIATIK.T "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 8 1014.571 4.88 10565 12468 2 1014.572458 508.2928 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 5.84 2845.7 - 414014 - - - 1.4765 - 2.091 0.393 - 230.7 1 2 0 0.0015 10 0 0 0 2.09E+07 4.29E+06 - - - 4.0022 0.9918 230117_WJC_METTL3_WT_vs_EV_F02.12475.12475.2 0.0584 14-Aug R.LPLQDVYK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 974.5437 5.77 10568 12475 2 974.548771 488.2791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2846.6 - 307805 - - - 5.2209 - 1.571 0.266 - 167.5 1 2 0 0.0051 8 0 0 0 2.57E+09 4.45E+08 - - - 2.3664 0.9862 230117_WJC_METTL3_WT_vs_EV_F02.12498.12498.2 2.82 12-May R.IGTFDLK[136.11].Y "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN" 2 800.4524 0.15 10581 12498 2 800.453475 401.2335 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 5.84 2849.6 - 800799 - - - 1.3992 - 1.256 0.095 - 52.3 3 2 0 0.0011 7 0 0 0 2.08E+07 1.38E+08 - - - 0.2514 0.9798 230117_WJC_METTL3_WT_vs_EV_F02.12502.12502.2 0.184 12-Jul K.TC[160.03]PLLLR[166.11].V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 881.5032 1.25 10583 12502 2 881.502339 441.7589 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2850.1 - 638871 - - - -1.0096 - 1.315 0.104 - 174.7 1 2 0 -0.0009 7 0 0 0 1.30E+09 1.04E+09 - - - 0.6765 0.9855 230117_WJC_METTL3_WT_vs_EV_F02.12503.12503.2 1.14 14-Jun K.AGLYGLPR[166.11].R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|A0A0U1RRG3|A0A0U1RRG3_HUMAN" 3 855.4842 2.19 10584 12503 2 855.485249 428.7494 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.79 2850.2 - 371429 - - - 1.2169 - 1.146 0.122 - 81.9 2 2 0 0.001 8 0 0 0 4.14E+08 1.89E+08 - - - 0.2183 0.9834 230117_WJC_METTL3_WT_vs_EV_F02.12512.12512.2 0.0344 12-Jun R.IGTFDLK.Y "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN" 2 792.4382 0.27 10590 12512 2 792.442454 397.2264 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 5.84 2851.3 - 725802 - - - 5.425 - 1.229 0.287 - 68.4 1 2 0 0.0043 7 0 0 0 2.01E+07 7.41E+07 - - - 1.8128 0.8638 230117_WJC_METTL3_WT_vs_EV_F02.12513.12513.2 12 12-May R.GDIQTLK.N sp|Q9HC62|SENP2_HUMAN 1 773.4283 0.85 10591 12513 2 773.429681 387.7214 Sentrin-specific protease 2 OS=Homo sapiens OX=9606 GN=SENP2 PE=1 SV=3 5.84 2851.4 - 599879 - - - 1.761 - 1.064 0.008 - 97.9 16 2 0 0.0014 7 0 0 0 3.97E+08 4.69E+08 - - - -1.2417 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.12517.12517.2 0.0169 12-Jun K.TC[160.03]PLLLR.V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 871.495 1.24 10593 12517 2 871.494219 436.7548 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2852 - 1.38E+06 - - - -0.8491 - 1.426 0.345 - 174.3 1 2 0 -0.0007 7 0 0 0 1.30E+09 1.04E+09 - - - 2.7134 0.9927 230117_WJC_METTL3_WT_vs_EV_F02.12518.12518.2 0.635 12-Jun R.GDIQTLK[136.11].N sp|Q9HC62|SENP2_HUMAN 1 781.4425 1.02 10594 12518 2 781.443389 391.7285 Sentrin-specific protease 2 OS=Homo sapiens OX=9606 GN=SENP2 PE=1 SV=3 5.84 2852.1 - 1.15E+06 - - - 1.1133 - 1.24 0.132 - 184.9 1 2 0 0.0009 7 0 0 0 5.39E+08 5.31E+08 - - - 0.6973 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.12521.12521.2 0.0014 16-Aug R.LYEALTPVH.- "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1041.5495 - 10595 12521 2 1041.551488 521.782 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.24 2852.5 - 767362 - - - 1.9125 - 1.414 0.361 - 196.3 1 2 0 0.002 9 0 0 0 - - - - - 2.7089 0.993 230117_WJC_METTL3_WT_vs_EV_F02.12522.12522.2 0.183 12-Jun K.VLFTVGK.L sp|Q9Y4C2|TCAF1_HUMAN 1 762.464 1.98 10596 12522 2 762.466613 382.2393 TRPM8 channel-associated factor 1 OS=Homo sapiens OX=9606 GN=TCAF1 PE=1 SV=3 8.72 2852.6 - 633300 - - - 3.4585 - 1.391 0.179 - 110.4 1 2 0 0.0026 7 0 0 0 2.22E+07 1.12E+07 - - - 1.408 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.12526.12526.2 1.16 14-Jul R.LPLQDVYK[136.11].L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 982.5579 5.74 10598 12526 2 982.559917 492.2862 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2853.1 - 840995 - - - 2.0701 - 1.557 0.112 - 170.5 1 2 0 0.002 8 0 0 0 2.55E+09 4.45E+08 - - - 1.2029 0.9952 230117_WJC_METTL3_WT_vs_EV_F02.12552.12552.2 0.167 14-Jul K.LSAAIVLK[136.11].N sp|Q8WUM0|NU133_HUMAN 1 821.5466 1.82 10605 12552 2 821.548147 411.7806 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 8.75 2857.1 - 729373 - - - 1.8952 - 1.404 0.183 - 72.2 6 2 0 0.0016 8 0 0 0 5.25E+07 2.89E+07 - - - 1.0679 0.9871 230117_WJC_METTL3_WT_vs_EV_F02.12555.12555.2 0.0196 18-Jul R.TIAQDYGVLK.A "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1106.5972 1.5 10606 12555 2 1106.602508 554.3059 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.5 2857.5 - 146093 - - - 4.8193 - 1.299 0.258 - 115.8 1 2 0 0.0053 10 0 0 0 1.19E+07 7.94E+06 - - - 1.6751 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.12568.12568.2 0.016 14-Aug K.AGLYGLPR.R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|A0A0U1RRG3|A0A0U1RRG3_HUMAN" 3 845.4759 2.38 10612 12568 2 845.47675 423.7452 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.79 2859.3 - 7.66E+06 - - - 0.9604 - 1.656 0.396 - 203.8 1 2 0 0.0008 8 0 0 0 4.50E+08 1.89E+08 - - - 3.4869 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.12579.12579.4 0.000132 11/108 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 3.44 10616 12579 4 2080.021593 521.0129 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2860.8 - 405722 - - - -0.4519 - 1.728 0.436 - 58.9 1 2 0 -0.0009 19 0 0 0 4.50E+07 1.31E+07 - - - 3.2057 0.9964 230117_WJC_METTL3_WT_vs_EV_F02.12587.12587.2 0.153 14-Jul K.IPYTTVLR.L "sp|Q08945|SSRP1_HUMAN,tr|E9PMD4|E9PMD4_HUMAN" 2 961.5597 0.27 10620 12587 2 961.560929 481.7871 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 8.75 2861.8 - 373413 - - - 1.3125 - 1.271 0.198 - 156.2 1 2 0 0.0013 8 0 0 0 1.28E+08 4.80E+08 - - - 1.2263 0.9908 230117_WJC_METTL3_WT_vs_EV_F02.12592.12592.2 0.259 18-Aug R.TIAQDYGVLK[136.11].A "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1114.6114 1.59 10622 12592 2 1114.610772 558.313 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.5 2862.4 - 149394 - - - -0.541 - 1.234 0.192 - 110.7 1 2 0 -0.0006 10 0 0 0 1.36E+07 8.53E+06 - - - 1.0458 0.9962 230117_WJC_METTL3_WT_vs_EV_F02.12598.12598.2 0.555 12-Jun R.WLGEPIK.A "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 841.4698 0.46 10624 12598 2 841.470866 421.7422 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6 2863.2 - 4.43E+06 - - - 1.2787 - 1.141 0.234 - 197.1 1 2 0 0.0011 7 0 0 0 1.25E+09 2.72E+09 - - - 1.1869 1 230117_WJC_METTL3_WT_vs_EV_F02.12600.12600.3 3.44E-07 13/72 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 4.04 10625 12600 3 2080.028347 694.3481 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2863.4 - 272344 - - - 2.7952 - 2.371 0.613 - 156.2 1 2 0 0.0058 19 0 0 0 1.21E+07 2.99E+06 - - - 7.4937 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.12606.12606.2 0.0659 20-Jul R.TAAENDFVTLK.K sp|P35908|K22E_HUMAN 1 1207.6085 9.76 10626 12606 2 1207.608895 604.8115 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2864.4 - 83040.4 - - - 0.3536 - 1.463 0.311 - 85 1 2 0 0.0004 11 0 0 0 4.38E+06 4.48E+05 - - - 2.3672 0.9168 230117_WJC_METTL3_WT_vs_EV_F02.12618.12618.2 0.0223 14-Aug L.VDHALIAR[166.11].C sp|Q05BV3|EMAL5_HUMAN 1 903.5166 4.11 10630 12618 2 903.517086 452.7656 Echinoderm microtubule-associated protein-like 5 OS=Homo sapiens OX=9606 GN=EML5 PE=2 SV=3 6.71 2866 - 950542 - - - 0.5711 - 1.604 0.26 - 220.3 1 1 0 0.0005 8 0 0 0 1.88E+08 4.57E+07 - - - 2.3862 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.12619.12619.2 0.0597 16-Oct K.AGLAPLEVR.V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 924.5393 0.75 10631 12619 2 924.540054 463.2769 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.05 2866.1 - 476349 - - - 0.8523 - 1.873 0.204 - 259.1 1 2 0 0.0008 9 0 0 0 2.48E+07 3.30E+07 - - - 2.363 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.12622.12622.2 0.042 12-Jul R.VAFLVSR.L sp|Q6ICC9|RTL6_HUMAN 1 790.4701 0.53 10632 12622 2 790.470653 396.2423 Retrotransposon Gag-like protein 6 OS=Homo sapiens OX=9606 GN=RTL6 PE=2 SV=1 9.72 2866.5 - 931704 - - - 0.6692 - 1.532 0.311 - 150.8 1 2 0 0.0005 7 0 0 0 3.19E+07 6.03E+07 - - - 2.6895 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.12623.12623.2 0.114 16-Aug K.AGLAPLEVR[166.11].V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 934.5475 0.75 10633 12623 2 934.547679 468.281 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.05 2866.7 - 514477 - - - 0.153 - 1.613 0.263 - 167.2 1 2 0 0.0001 9 0 0 0 2.61E+07 3.47E+07 - - - 2.3666 0.9651 230117_WJC_METTL3_WT_vs_EV_F02.12639.12639.2 5.01 16-Jun K.LVPVGYGIR[166.11].K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 982.5839 0.97 10641 12639 2 982.585913 492.2992 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2868.4 - 5.09E+06 - - - 2.0263 - 1.004 0.089 - 97.9 1 2 0 0.002 9 0 0 0 7.98E+08 8.21E+08 - - - -0.2907 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.12645.12645.2 0.0371 16-Sep K.IGPLGLSPK[136.11].K sp|P30050|RL12_HUMAN 1 888.5524 1.63 10644 12645 2 888.552076 445.2835 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2869.1 - 2.28E+06 - - - -0.368 - 1.522 0.264 - 161 1 2 0 -0.0003 9 0 0 0 1.23E+10 7.58E+09 - - - 2.206 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.12657.12657.2 0.0358 16-Sep K.IGPLGLSPK.K sp|P30050|RL12_HUMAN 1 880.5382 1.62 10648 12657 2 880.538602 441.2764 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2870.9 - 8.69E+06 - - - 0.4531 - 1.577 0.282 - 235.7 1 2 0 0.0004 9 0 0 0 1.24E+10 7.63E+09 - - - 2.4416 0.995 230117_WJC_METTL3_WT_vs_EV_F02.12669.12669.2 0.303 12-Jun K.FLEPTLR.L "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 874.4913 1.04 10651 12669 2 874.493014 438.2529 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 2872.6 - 9.33E+06 - - - 2.0137 - 1.353 0.143 - 177.7 1 2 0 0.0018 7 0 0 0 4.01E+08 3.87E+08 - - - 1.0546 0.997 230117_WJC_METTL3_WT_vs_EV_F02.12673.12673.2 0.159 12-Aug R.LAILYAK.R "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 790.4953 1.11 10653 12673 2 790.495113 396.2549 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 8.59 2873.1 - 790221 - - - -0.2062 - 1.876 0.106 - 205.1 1 2 0 -0.0002 7 0 0 0 2.51E+08 2.27E+08 - - - 1.8173 0.9956 230117_WJC_METTL3_WT_vs_EV_F02.12674.12674.2 0.147 12-Jun R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 138.85 10654 12674 2 776.381812 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2873.2 - 790713 - - - 0.1404 - 1.338 0.184 - 112.4 1 2 0 0.0001 7 0 0 0 1.16E+09 8.33E+06 - - - 1.3226 0.9732 230117_WJC_METTL3_WT_vs_EV_F02.12680.12680.2 7.08 16-Jul K.LVPVGYGIR.K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 972.5757 0.97 10656 12680 2 972.575323 487.2951 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2874 - 1.08E+07 - - - -0.3383 - 1.185 0.089 - 172.9 1 2 0 -0.0003 9 0 0 0 8.03E+08 8.28E+08 - - - 0.1893 0.997 230117_WJC_METTL3_WT_vs_EV_F02.12691.12691.2 0.264 14-Oct R.LGNSLLLK.Y sp|Q10570|CPSF1_HUMAN 1 856.5382 0.29 10660 12691 2 856.537472 429.2764 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 2875.5 - 1.55E+06 - - - -0.8534 - 1.573 0.239 - 184.7 1 2 0 -0.0007 8 0 0 0 1.23E+08 4.28E+08 - - - 2.1722 0.9944 230117_WJC_METTL3_WT_vs_EV_F02.12720.12720.2 0.425 12-Oct K.TAISLLR[166.11].N sp|Q99959|PKP2_HUMAN 1 782.489 1.04 10665 12720 2 782.491951 392.2518 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 9.41 2879.9 - 687751 - - - 3.8237 - 1.783 0.127 - 277.3 1 2 0 0.003 7 0 0 0 8.20E+07 7.88E+07 - - - 1.8104 0.9901 230117_WJC_METTL3_WT_vs_EV_F02.12738.12738.2 2.79 14-Aug R.LPVDIAYK.R sp|P15924|DESP_HUMAN 1 917.5222 5.66 10671 12738 2 917.520981 459.7684 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.83 2882.3 - 1.42E+06 - - - -1.3493 - 1.42 0.175 - 191.8 1 2 0 -0.0012 8 0 0 0 3.37E+08 5.95E+07 - - - 1.3907 0.9965 230117_WJC_METTL3_WT_vs_EV_F02.12739.12739.2 0.00627 18-Sep R.LIAAATSVLK[136.11].T "sp|P24863|CCNC_HUMAN,tr|E5RFX8|E5RFX8_HUMAN,tr|E5RI39|E5RI39_HUMAN,tr|J3KP90|J3KP90_HUMAN,tr|E5RFK5|E5RFK5_HUMAN,tr|G5E954|G5E954_HUMAN,tr|H0YBQ5|H0YBQ5_HUMAN" 7 993.6314 1.55 10672 12739 2 993.629387 497.823 Cyclin-C OS=Homo sapiens OX=9606 GN=CCNC PE=1 SV=2 8.75 2882.5 - 418512 - - - -2.0078 - 1.716 0.31 - 138.2 1 2 0 -0.002 10 0 0 0 1.41E+07 9.11E+06 - - - 2.8373 0.9016 230117_WJC_METTL3_WT_vs_EV_F02.12760.12760.2 0.258 14-Sep D.IADIEALK.E "sp|Q70CQ2|UBP34_HUMAN,sp|O75792|RNH2A_HUMAN,tr|A0A2R8Y606|A0A2R8Y606_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 4 871.5015 1.69 10682 12760 2 871.50141 436.758 Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens OX=9606 GN=USP34 PE=1 SV=2 4.37 2885.1 - 3.71E+06 - - - -0.0849 - 1.787 0.233 - 189 1 1 0 -0.0001 8 0 0 0 3.37E+08 1.99E+08 - - - 2.5128 0.9706 230117_WJC_METTL3_WT_vs_EV_F02.12762.12762.2 0.165 14-Jul K.FGELVMTK.E "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 923.4786 3.24 10684 12762 2 923.477311 462.7466 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6 2885.2 - 1.13E+06 - - - -1.4391 - 1.032 0.198 - 129.1 1 2 0 -0.0013 8 0 0 0 1.98E+08 6.12E+07 - - - 0.598 0.9052 230117_WJC_METTL3_WT_vs_EV_F02.12768.12768.2 1.91 12-May R.LVNQWIK.Q "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 899.5229 0.79 10688 12768 2 899.524836 450.7687 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 8.75 2886 - 1.00E+06 - - - 2.1656 - 0.988 0.011 - 64.5 1 2 0 0.0019 7 0 0 0 2.90E+07 3.67E+07 - - - -0.9166 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.12778.12778.2 0.167 14-Sep K.TALLGLTK[136.11].T sp|Q9BTZ2|DHRS4_HUMAN 1 823.5259 0.95 10693 12778 2 823.52602 412.7702 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 8.41 2887.2 - 2.52E+07 - - - 0.2016 - 1.563 0.174 - 354.3 1 2 0 0.0002 8 0 0 0 7.50E+08 7.93E+08 - - - 1.6731 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.12782.12782.2 0.127 14-Aug K.FGELVMTK[136.11].E "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 931.4928 3.25 10695 12782 2 931.49375 466.7537 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6 2887.7 - 1.25E+06 - - - 0.9769 - 1.347 0.236 - 152.6 1 2 0 0.0009 8 0 0 0 2.01E+08 6.20E+07 - - - 1.6822 0.9826 230117_WJC_METTL3_WT_vs_EV_F02.12800.12800.2 0.148 20-Jun R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 999 10701 12800 2 1068.658827 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 2890 - 3.71E+06 - - - 4.2399 - 1.518 0.162 - 72.8 4 2 0 0.0045 11 0 0 0 6.80E+08 0.00E+00 - - - 1.0963 0.9951 230117_WJC_METTL3_WT_vs_EV_F02.12813.12813.2 0.232 12-Jul K.LYALDVR.V "sp|O94913|PCF11_HUMAN,tr|E9PKN0|E9PKN0_HUMAN,tr|E9PQF9|E9PQF9_HUMAN,tr|E9PQ01|E9PQ01_HUMAN" 4 848.4756 0.74 10705 12813 2 848.475519 425.2451 Pre-mRNA cleavage complex 2 protein Pcf11 OS=Homo sapiens OX=9606 GN=PCF11 PE=1 SV=3 5.84 2891.8 - 581337 - - - -0.099 - 1.349 0.182 - 125.4 1 2 0 -0.0001 7 0 0 0 2.32E+07 3.14E+07 - - - 1.3338 0.9862 230117_WJC_METTL3_WT_vs_EV_F02.12815.12815.2 2.72 14-Jul K.ILGDLSYR.S "sp|Q9NVC6|MED17_HUMAN,tr|A0A1W2PNF3|A0A1W2PNF3_HUMAN,tr|E9PM72|E9PM72_HUMAN,tr|A0A1W2PQ48|A0A1W2PQ48_HUMAN,tr|A0A1W2PS27|A0A1W2PS27_HUMAN,tr|A0A1W2PR99|A0A1W2PR99_HUMAN,tr|A0A1W2PRB8|A0A1W2PRB8_HUMAN,tr|A0A1W2PPP8|A0A1W2PPP8_HUMAN,tr|A0A1W2PNW7|A0A1W2PNW7_HUMAN,tr|A0A1W2PS69|A0A1W2PS69_HUMAN,tr|A0A1W2PRX4|A0A1W2PRX4_HUMAN" 11 935.5076 1.41 10706 12815 2 935.507682 468.7611 Mediator of RNA polymerase II transcription subunit 17 OS=Homo sapiens OX=9606 GN=MED17 PE=1 SV=2 5.84 2892 - 1.40E+06 - - - 0.0534 - 1.106 0.156 - 117.6 1 2 0 0.0001 8 0 0 0 2.62E+07 1.86E+07 - - - 0.4971 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.12827.12827.2 0.185 20-Nov K.LIADVAPSAIR[166.11].E "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1134.6636 1.76 10711 12827 2 1134.66429 568.3391 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 5.84 2893.5 - 712711 - - - 0.5826 - 2.023 0.239 - 339.1 1 2 0 0.0007 11 0 0 0 5.12E+07 2.91E+07 - - - 2.7121 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.12829.12829.2 0.0513 18-Oct R.ISGLIYEETR[166.11].G sp|P62805|H4_HUMAN 1 1189.6218 0.64 10712 12829 2 1189.620805 595.8182 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2893.7 - 286486 - - - -0.8557 - 2.22 0.352 - 305.9 1 2 0 -0.001 10 0 0 0 1.03E+07 1.60E+07 - - - 3.8666 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.12833.12833.4 0.00506 Nov-96 T.LLLIILTDVFIISTVLR.L sp|Q8NGY0|O10X1_HUMAN 1 1941.2278 1.84 10714 12833 4 1941.233592 486.3142 Olfactory receptor 10X1 OS=Homo sapiens OX=9606 GN=OR10X1 PE=3 SV=2 5.84 2894.2 - 720807 - - - 2.9723 - 1.671 0.454 - 30.5 1 1 0 0.0058 17 0 0 0 6.39E+07 3.47E+07 - - - 3.3543 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.12857.12857.2 7.55 16-Sep K.AIPLALEGK[136.11].D "sp|Q9NY93|DDX56_HUMAN,tr|F8WDT8|F8WDT8_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|F8WEI3|F8WEI3_HUMAN" 4 918.563 1.05 10723 12857 2 918.563447 460.2888 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 6.05 2897.5 - 581616 - - - 0.5215 - 1.467 0.192 - 202.5 1 2 0 0.0005 9 0 0 0 2.80E+07 2.66E+07 - - - 1.5676 0.9922 230117_WJC_METTL3_WT_vs_EV_F02.12858.12858.2 0.0663 14-Jun R.VIAQLEIR.Q "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|E9PLY5|E9PLY5_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A669KBB0|A0A669KBB0_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A5F9ZGX0|A0A5F9ZGX0_HUMAN" 10 940.5706 4.53 10724 12858 2 940.57266 471.2926 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.97 2897.6 - 492776 - - - 2.2263 - 1.27 0.157 - 70.9 2 2 0 0.0021 8 0 0 0 1.20E+07 2.65E+06 - - - 0.7863 0.9957 230117_WJC_METTL3_WT_vs_EV_F02.12879.12879.2 0.427 12-Sep K.TELLGLK.E sp|Q69YU5|BWNIN_HUMAN 1 772.4695 1.42 10733 12879 2 772.471982 387.242 Protein BRAWNIN OS=Homo sapiens OX=9606 GN=BRAWNIN PE=1 SV=2 5.66 2900.4 - 1.46E+06 - - - 3.2713 - 1.517 0.186 - 366 1 2 0 0.0025 7 0 0 0 5.34E+07 3.76E+07 - - - 1.7344 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.12885.12885.2 0.297 12-Sep K.TELLGLK[136.11].E sp|Q69YU5|BWNIN_HUMAN 1 780.4837 1.46 10737 12885 2 780.485486 391.2491 Protein BRAWNIN OS=Homo sapiens OX=9606 GN=BRAWNIN PE=1 SV=2 5.66 2901.1 - 1.01E+06 - - - 2.346 - 1.655 0.166 - 364.7 1 2 0 0.0018 7 0 0 0 5.10E+07 3.49E+07 - - - 1.8628 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.12890.12890.2 0.0131 16-Aug R.LVPLVNGVR.E "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 965.6022 2.97 10740 12890 2 965.604916 483.8084 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 9.75 2901.7 - 1.73E+06 - - - 2.8117 - 1.635 0.38 - 235.3 1 2 0 0.0027 9 0 0 0 1.17E+08 3.95E+07 - - - 3.2692 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.12892.12892.2 0.0113 16-Aug K.AFADPEVLR.R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1016.5291 2.9 10742 12892 2 1016.532928 509.2718 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2901.9 - 425228 - - - 3.7707 - 1.404 0.273 - 235.7 1 2 0 0.0038 9 0 0 0 7.95E+07 2.74E+07 - - - 2.0379 0.9956 230117_WJC_METTL3_WT_vs_EV_F02.12893.12893.2 0.408 12-Jul R.VFLQQLK.G "sp|Q13487|SNPC2_HUMAN,tr|M0QXY9|M0QXY9_HUMAN" 2 874.5276 0.1 10743 12893 2 874.529237 438.2711 snRNA-activating protein complex subunit 2 OS=Homo sapiens OX=9606 GN=SNAPC2 PE=1 SV=1 8.72 2902 - 282407 - - - 1.8273 - 1.29 0.171 - 114.6 1 2 0 0.0016 7 0 0 0 1.07E+07 1.10E+08 - - - 1.1104 0.9845 230117_WJC_METTL3_WT_vs_EV_F02.12894.12894.2 0.00566 14-Jul K.FQNALLVR.Y "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 959.5553 3612.82 10744 12894 2 959.561149 480.7849 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 9.75 2902.1 - 194303 - - - 6.1476 - 1.543 0.272 - 139.7 1 2 0 0.0059 8 0 0 0 1.13E+08 3.13E+04 - - - 2.3562 0.9452 230117_WJC_METTL3_WT_vs_EV_F02.12901.12901.2 0.25 14-Sep K.LISGWVSR[166.11].S "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 926.5213 3.45 10749 12901 2 926.526591 464.2679 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 9.75 2902.9 - 346485 - - - 5.6879 - 1.262 0.164 - 164.8 1 2 0 0.0053 8 0 0 0 1.37E+08 3.97E+07 - - - 0.9525 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.12902.12902.2 2.31E-05 26-Oct R.LVPGGGATEIELAK.Q sp|P50990|TCPQ_HUMAN 1 1353.7504 24.23 10750 12902 2 1353.754681 677.8825 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 2903.1 - 293865 - - - 3.1764 - 1.998 0.486 - 200.2 1 2 0 0.0043 14 0 0 0 2.85E+07 1.17E+06 - - - 4.3662 0.9882 230117_WJC_METTL3_WT_vs_EV_F02.12907.12907.2 3.22 12-May R.TILMMGR.Y sp|P13639|EF2_HUMAN 1 820.4299 1.51 10753 12907 2 820.431951 411.2222 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 9.41 2903.7 - 5.32E+06 - - - 2.4816 - 1.122 0.158 - 96.7 1 2 0 0.002 7 0 0 0 1.56E+08 1.04E+08 - - - 0.5721 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.12913.12913.2 0.000545 16-Aug K.AFADPEVLR[166.11].R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1026.5374 2.77 10757 12913 2 1026.540705 514.276 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2904.4 - 549516 - - - 3.2537 - 1.552 0.427 - 222.6 1 2 0 0.0033 9 0 0 0 7.61E+07 2.74E+07 - - - 3.4654 0.9641 230117_WJC_METTL3_WT_vs_EV_F02.12914.12914.2 2.14 12-Jun R.LLEIVER.Q sp|Q12792|TWF1_HUMAN 1 870.5175 1.28 10758 12914 2 870.521388 436.266 Twinfilin-1 OS=Homo sapiens OX=9606 GN=TWF1 PE=1 SV=3 4.53 2904.5 - 485741 - - - 4.5031 - 1.447 0.064 - 118.3 1 2 0 0.0039 7 0 0 0 4.97E+07 3.89E+07 - - - 0.6832 0.8972 230117_WJC_METTL3_WT_vs_EV_F02.12915.12915.2 0.369 18-Aug R.RVLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1125.687 1.48 10759 12915 2 1125.695595 563.8508 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2904.6 - 218300 - - - 7.6416 - 1.602 0.134 - 172.7 1 2 0 0.0086 10 0 0 0 3.54E+07 2.39E+07 - - - 1.3434 0.9915 230117_WJC_METTL3_WT_vs_EV_F02.12921.12921.2 0.159 14-Jul K.LISGWVSR.S "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 916.5131 1.46 10763 12921 2 916.51747 459.2638 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 9.75 2905.3 - 1.02E+06 - - - 4.8215 - 1.381 0.277 - 125.3 1 2 0 0.0044 8 0 0 0 5.71E+07 3.91E+07 - - - 2.0591 0.9915 230117_WJC_METTL3_WT_vs_EV_F02.12930.12930.2 0.771 14-Jul R.ILLVGEPR.V "sp|Q8IXI2|MIRO1_HUMAN,tr|J3KSR5|J3KSR5_HUMAN" 2 895.5491 1.45 10768 12930 2 895.551623 448.7818 Mitochondrial Rho GTPase 1 OS=Homo sapiens OX=9606 GN=RHOT1 PE=1 SV=2 6 2906.6 - 183575 - - - 2.815 - 1.389 0.124 - 127 1 2 0 0.0025 8 0 0 0 2.46E+07 1.70E+07 - - - 0.9471 0.9026 230117_WJC_METTL3_WT_vs_EV_F02.12933.12933.2 4.66 14-Jul R.IAYLSEVK.E sp|P36508|ZNF76_HUMAN 1 921.5171 10.1 10770 12933 2 921.519812 461.7658 Zinc finger protein 76 OS=Homo sapiens OX=9606 GN=ZNF76 PE=1 SV=2 6 2906.9 - 460345 - - - 2.9061 - 1.083 0.021 - 78.6 2 2 0 0.0027 8 0 0 0 3.91E+07 3.87E+06 - - - -0.6987 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.12934.12934.2 0.144 16-Jul R.LVPLVNGVR[166.11].E "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 975.6105 2.97 10771 12934 2 975.613114 488.8125 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 9.75 2907 - 1.30E+06 - - - 2.7091 - 1.289 0.256 - 119.6 1 2 0 0.0026 9 0 0 0 1.17E+08 3.95E+07 - - - 1.6654 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.12956.12956.2 0.149 16-Jul K.MLVVGGIDR[166.11].V sp|Q15046|SYK_HUMAN 1 968.5353 1.12 10781 12956 2 968.537325 485.2749 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2909.9 - 2.60E+06 - - - 2.1352 - 1.6 0.307 - 216.8 1 2 0 0.0021 9 0 0 0 1.71E+08 1.53E+08 - - - 2.6676 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.12958.12958.2 3.13 12-Jun R.VAIFIEK.T sp|Q9P258|RCC2_HUMAN 1 818.4902 1.76 10782 12958 2 818.491913 410.2524 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2910.1 - 1.62E+06 - - - 2.1039 - 1.27 0.191 - 111.8 1 2 0 0.0017 7 0 0 0 9.38E+07 5.32E+07 - - - 1.2085 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.12966.12966.2 0.18 12-Aug R.VAIFIEK[136.11].T sp|Q9P258|RCC2_HUMAN 1 826.5044 1.77 10786 12966 2 826.504925 414.2595 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2911.2 - 1.45E+06 - - - 0.6461 - 1.962 0.145 - 231 1 2 0 0.0005 7 0 0 0 9.38E+07 5.30E+07 - - - 2.2473 0.9934 230117_WJC_METTL3_WT_vs_EV_F02.12973.12973.2 0.199 14-Aug R.SPAQILLR[166.11].W "sp|P14550|AK1A1_HUMAN,sp|Q96JD6|AKCL2_HUMAN,tr|G3V1C1|G3V1C1_HUMAN" 3 906.5526 4.38 10789 12973 2 906.552186 454.2836 Aldo-keto reductase family 1 member A1 OS=Homo sapiens OX=9606 GN=AKR1A1 PE=1 SV=3 9.47 2912.1 - 303783 - - - -0.4798 - 1.211 0.225 - 116.9 1 2 0 -0.0004 8 0 0 0 1.01E+08 2.31E+07 - - - 1.2801 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.12978.12978.2 0.0211 16-Aug K.MLVVGGIDR.V sp|Q15046|SYK_HUMAN 1 958.527 1.12 10791 12978 2 958.527421 480.2708 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2912.7 - 4.78E+06 - - - 0.4528 - 1.659 0.327 - 285.5 1 2 0 0.0004 9 0 0 0 1.72E+08 1.53E+08 - - - 2.9206 0.9643 230117_WJC_METTL3_WT_vs_EV_F02.12980.12980.2 1.1 12-May K.VLLGELK.G sp|Q05655|KPCD_HUMAN 1 770.4902 3.06 10792 12980 2 770.489514 386.2524 Protein kinase C delta type OS=Homo sapiens OX=9606 GN=PRKCD PE=1 SV=2 5.97 2912.9 - 731066 - - - -0.8787 - 1.228 0.134 - 89.9 11 2 0 -0.0007 7 0 0 0 3.45E+07 1.13E+07 - - - 0.2161 0.9881 230117_WJC_METTL3_WT_vs_EV_F02.12987.12987.2 1.01 12-Jun K.ELVTLYR.R sp|Q8TD55|PKHO2_HUMAN 1 892.5018 1.16 10795 12987 2 892.503512 447.2582 Pleckstrin homology domain-containing family O member 2 OS=Homo sapiens OX=9606 GN=PLEKHO2 PE=1 SV=1 6.1 2913.8 - 1.15E+06 - - - 1.898 - 1.244 0.091 - 151.6 1 2 0 0.0017 7 0 0 0 3.88E+07 3.33E+07 - - - 0.4044 0.9469 230117_WJC_METTL3_WT_vs_EV_F02.12992.12992.2 5.6 12-Jul K.TVYSILR[166.11].H "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 860.4995 0.65 10798 12992 2 860.499233 431.257 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 8.41 2914.4 - 2.25E+06 - - - -0.337 - 1.09 0.056 - 153.8 1 2 0 -0.0003 7 0 0 0 1.95E+08 3.01E+08 - - - -0.2724 0.9897 230117_WJC_METTL3_WT_vs_EV_F02.12993.12993.2 0.225 14-Jul K.GYGFGMVK[136.11].L "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RFL1|E5RFL1_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 6 865.4248 1.26 10799 12993 2 865.424538 433.7197 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 8.59 2914.5 - 832097 - - - -0.2565 - 1.113 0.199 - 67 1 2 0 -0.0002 8 0 0 0 3.12E+07 2.47E+07 - - - 0.8336 0.9794 230117_WJC_METTL3_WT_vs_EV_F02.13023.13023.2 1.91 14-Jul K.LEPVVFEK[136.11].V "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 967.547 3.39 10808 13023 2 967.546538 484.7808 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 2918.7 - 875645 - - - -0.461 - 1.213 0.108 - 148.8 1 2 0 -0.0004 8 0 0 0 1.16E+08 3.42E+07 - - - 0.4209 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.13034.13034.2 0.00655 14-Sep K.VVLVLAGR[166.11].Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 835.5519 0.78 10810 13034 2 835.551902 418.7832 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2920.5 - 5.48E+06 - - - 0.0108 - 1.817 0.341 - 294.8 1 2 0 0 8 0 0 0 1.97E+09 2.50E+09 - - - 3.3607 0.996 230117_WJC_METTL3_WT_vs_EV_F02.13036.13036.2 0.561 14-Aug K.FIINSYPK[136.11].Y "sp|Q96EY7|PTCD3_HUMAN,tr|B8ZZQ4|B8ZZQ4_HUMAN" 2 988.5473 0.89 10812 13036 2 988.548206 495.2809 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 8.59 2920.7 - 381731 - - - 0.8983 - 1.353 0.167 - 126.6 1 2 0 0.0009 8 0 0 0 1.50E+07 1.68E+07 - - - 1.186 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.13039.13039.2 0.0291 14-Sep K.VVLVLAGR.Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 825.5436 0.78 10813 13039 2 825.544008 413.7791 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2921.1 - 5.63E+06 - - - 0.4664 - 1.869 0.448 - 395.8 1 2 0 0.0004 8 0 0 0 1.97E+09 2.51E+09 - - - 4.236 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.13040.13040.2 0.773 14-Jul R.QMAAVLLR[166.11].R "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 11 910.5298 1.31 10814 13040 2 910.53 456.2722 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 2921.2 - 869979 - - - 0.2438 - 1.654 0.152 - 144.9 1 2 0 0.0002 8 0 0 0 6.81E+07 5.21E+07 - - - 1.6812 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.13049.13049.2 0.000823 18-Aug R.VNC[160.03]LAPGLIK[136.11].T "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN" 3 1091.6253 0.81 10821 13049 2 1091.62577 546.8199 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 8.19 2922.4 - 182778 - - - 0.4754 - 1.668 0.397 - 194.3 1 2 0 0.0005 10 0 0 0 6.96E+06 8.64E+06 - - - 3.4012 0.9359 230117_WJC_METTL3_WT_vs_EV_F02.13053.13053.2 2.52 12-Jun K.FEPTVFR[166.11].D "sp|Q9Y6E2|BZW2_HUMAN,tr|F8WDX8|F8WDX8_HUMAN,tr|E7EMS9|E7EMS9_HUMAN,tr|E9PFE3|E9PFE3_HUMAN,tr|E7ETZ4|E7ETZ4_HUMAN,tr|C9JF98|C9JF98_HUMAN,tr|Q75MG1|Q75MG1_HUMAN" 7 904.4682 0.61 10823 13053 2 904.467162 453.2414 Basic leucine zipper and W2 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=BZW2 PE=1 SV=1 6 2922.9 - 517773 - - - -1.1731 - 0.933 0.151 - 71.5 1 2 0 -0.0011 7 0 0 0 1.71E+07 2.80E+07 - - - -0.0638 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.13061.13061.2 0.016 14-Jul K.LTPVLLAK[136.11].Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 861.5779 1.55 10829 13061 2 861.578393 431.7962 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2923.7 - 4.57E+06 - - - 0.5838 - 1.253 0.262 - 163.3 1 2 0 0.0005 8 0 0 0 3.30E+08 2.12E+08 - - - 1.6562 0.9757 230117_WJC_METTL3_WT_vs_EV_F02.13064.13064.2 2.43 12-Jul R.AFGIPVR[166.11].C sp|Q00535|CDK5_HUMAN 1 768.4522 1.38 10832 13064 2 768.45322 385.2334 Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3 9.79 2924 - 741882 - - - 1.3547 - 1.157 0.05 - 150.1 1 2 0 0.001 7 0 0 0 9.59E+07 6.95E+07 - - - -0.128 0.866 230117_WJC_METTL3_WT_vs_EV_F02.13067.13067.2 0.0486 12-Jul K.PIIFDC[160.03]R[166.11].S "sp|P35232|PHB_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 4 929.4668 2.4 10833 13067 2 929.466476 465.7407 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 6.22 2924.4 - 134759 - - - -0.3949 - 1.366 0.312 - 159 1 1 0 -0.0004 7 0 0 0 8.79E+06 3.67E+06 - - - 2.3335 0.9618 230117_WJC_METTL3_WT_vs_EV_F02.13083.13083.2 0.0199 12-Jul R.LSSFIVK.E sp|P24278|ZBT25_HUMAN 1 792.4745 0.82 10842 13083 2 792.472779 397.2445 Zinc finger and BTB domain-containing protein 25 OS=Homo sapiens OX=9606 GN=ZBTB25 PE=1 SV=2 8.75 2926.5 - 1.68E+06 - - - -2.2234 - 1.672 0.031 - 110.4 2 2 0 -0.0018 7 0 0 0 5.29E+07 6.47E+07 - - - 0.7636 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.13088.13088.2 0.374 14-Jun K.LTPVLLAK.Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 853.5637 1.55 10845 13088 2 853.564189 427.7891 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2927.1 - 4.87E+06 - - - 0.5846 - 1.092 0.261 - 91.2 1 2 0 0.0005 8 0 0 0 3.30E+08 2.12E+08 - - - 1.234 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.13090.13090.3 0.143 14/40 K.FAAQELIEVKR.G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1302.7296 48 10847 13090 3 1302.731752 435.2505 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2927.4 - 922413 - - - 1.6627 - 2.171 0.146 - 152.6 1 2 0 0.0022 11 0 0 0 5.58E+07 1.16E+06 - - - 2.3693 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.13091.13091.2 1.14 14-Sep K.LLAEVTLK[136.11].T "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 4 893.5677 2.67 10848 13091 2 893.569185 447.7911 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 6 2927.5 - 497340 - - - 1.6406 - 1.348 0.227 - 185.6 1 2 0 0.0015 8 0 0 0 1.78E+08 6.67E+07 - - - 1.6178 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.13095.13095.2 0.0238 12-Aug R.FASFIER[166.11].V sp|P07196|NFL_HUMAN 1 878.4526 1.43 10850 13095 2 878.453066 440.2336 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2928 - 1.15E+06 - - - 0.5612 - 1.736 0.249 - 211 1 2 0 0.0005 7 0 0 0 1.05E+08 7.35E+07 - - - 2.6277 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.13101.13101.2 0.0469 14-Aug K.LLAEVTLK.T "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 4 885.5535 2.67 10854 13101 2 885.55446 443.784 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 6 2928.7 - 2.07E+06 - - - 1.0626 - 1.406 0.303 - 148 1 2 0 0.0009 8 0 0 0 1.78E+08 6.67E+07 - - - 2.3063 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.13113.13113.2 0.756 14-Aug K.IADFGLAR.L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 861.4709 2.36 10861 13113 2 861.470964 431.7427 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2930.2 - 1.19E+06 - - - 0.13 - 1.739 0.199 - 155.5 2 2 0 0.0001 8 0 0 0 1.25E+08 5.31E+07 - - - 2.0451 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.13118.13118.2 0.341 14-Jul R.IFNTFGPR[166.11].M "sp|Q8NBZ7|UXS1_HUMAN,tr|C9JCB7|C9JCB7_HUMAN,tr|C9JFU6|C9JFU6_HUMAN,tr|C9JE50|C9JE50_HUMAN" 4 960.5057 0.76 10863 13118 2 960.505732 481.2601 UDP-glucuronic acid decarboxylase 1 OS=Homo sapiens OX=9606 GN=UXS1 PE=1 SV=1 9.75 2930.9 - 477412 - - - 0.0635 - 1.485 0.288 - 109.5 1 2 0 0.0001 8 0 0 0 3.74E+07 4.92E+07 - - - 2.3607 0.9947 230117_WJC_METTL3_WT_vs_EV_F02.13120.13120.2 0.0249 20-Jul K.YGQISEVVVVK[136.11].D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1227.6954 0.9 10864 13120 2 1227.699255 614.855 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2931.1 - 168027 - - - 3.1083 - 1.156 0.274 - 121.5 1 2 0 0.0038 11 0 0 0 5.97E+06 6.65E+06 - - - 1.4557 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.13122.13122.2 0.356 12-Jul R.FASFIER.V sp|P07196|NFL_HUMAN 1 868.4443 1.42 10866 13122 2 868.445365 435.2294 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2931.3 - 3.51E+06 - - - 1.2229 - 1.507 0.105 - 150.9 1 2 0 0.0011 7 0 0 0 1.04E+08 7.35E+07 - - - 1.1157 0.9966 230117_WJC_METTL3_WT_vs_EV_F02.13136.13136.2 0.0281 12-Jul K.VVIDAFR.L sp|O00487|PSDE_HUMAN 1 818.465 1.95 10874 13136 2 818.466394 410.2398 26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1 5.81 2933.1 - 5.90E+06 - - - 1.6568 - 1.382 0.166 - 230.8 1 2 0 0.0014 7 0 0 0 3.92E+08 2.01E+08 - - - 1.2918 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.13142.13142.2 0.945 12-Jul K.ILMEFNK[136.11].M sp|Q9UQE7|SMC3_HUMAN 1 901.4823 1.53 10875 13142 2 901.482985 451.7484 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2934 - 573896 - - - 0.7876 - 1.227 0.201 - 108.9 1 2 0 0.0007 7 0 0 0 7.06E+07 4.61E+07 - - - 1.1736 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.13143.13143.2 4.77E-06 20-Oct K.YGQISEVVVVK.D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1219.6812 0.9 10876 13143 2 1219.684647 610.8479 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2934.1 - 150330 - - - 2.7942 - 2.019 0.473 - 305.5 1 2 0 0.0034 11 0 0 0 5.97E+06 6.65E+06 - - - 4.4342 0.9876 230117_WJC_METTL3_WT_vs_EV_F02.13144.13144.2 0.861 12-Jul K.ILMEFNK.M sp|Q9UQE7|SMC3_HUMAN 1 893.4681 1.73 10877 13144 2 893.469912 447.7413 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2934.2 - 1.44E+06 - - - 2.056 - 1.139 0.129 - 102.3 1 2 0 0.0018 7 0 0 0 6.93E+07 4.02E+07 - - - 0.4056 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.13147.13147.2 2.44 14-Jul K.LALDYGIK[136.11].F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 899.5208 0.83 10878 13147 2 899.521569 450.7677 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 2934.6 - 685786 - - - 0.8894 - 1.521 0.142 - 95.7 1 2 0 0.0008 8 0 0 0 4.00E+07 4.81E+07 - - - 1.3544 0.997 230117_WJC_METTL3_WT_vs_EV_F02.13156.13156.2 0.174 14-Aug K.IGDFGLAR.D "sp|P08922|ROS1_HUMAN,sp|P07333|CSF1R_HUMAN,sp|P51617|IRAK1_HUMAN,sp|Q96PY6|NEK1_HUMAN,sp|P51955|NEK2_HUMAN,sp|Q6P3R8|NEK5_HUMAN,sp|Q16659|MK06_HUMAN,sp|P31152|MK04_HUMAN,tr|E9PIX7|E9PIX7_HUMAN,tr|H7C2I6|H7C2I6_HUMAN,tr|K7EN18|K7EN18_HUMAN,tr|A0A494C168|A0A494C168_HUMAN,tr|F6U4U2|F6U4U2_HUMAN,tr|H7C224|H7C224_HUMAN,tr|K7ELV1|K7ELV1_HUMAN,tr|Q5H8Y1|Q5H8Y1_HUMAN,tr|A0A3B3ITQ6|A0A3B3ITQ6_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 18 847.4552 2.42 10882 13156 2 847.455802 424.7349 Proto-oncogene tyrosine-protein kinase ROS OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3 5.84 2935.8 - 1.11E+06 - - - 0.708 - 1.896 0.063 - 171.6 1 2 0 0.0006 8 0 0 0 8.33E+07 3.44E+07 - - - 1.4356 0.9933 230117_WJC_METTL3_WT_vs_EV_F02.13158.13158.2 2.97 14-May K.VLPITVPK[136.11].S sp|Q9ULW0|TPX2_HUMAN 1 873.5779 2.05 10883 13158 2 873.578919 437.7962 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.72 2936 - 734314 - - - 1.1779 - 0.841 0.322 - 33.7 2 2 0 0.001 8 0 0 0 6.86E+07 3.35E+07 - - - 0.7622 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.13163.13163.2 2.07 12-Jul R.LALEELR.S sp|Q99496|RING2_HUMAN 1 842.4862 1.05 10886 13163 2 842.486757 422.2504 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.53 2936.6 - 933509 - - - 0.6991 - 1.605 0.114 - 174.2 1 2 0 0.0006 7 0 0 0 3.01E+08 2.87E+08 - - - 1.3819 0.9493 230117_WJC_METTL3_WT_vs_EV_F02.13172.13172.2 0.0783 16-Aug Y.GYIVAAVVK.L sp|Q8NGI9|OR5A2_HUMAN 1 918.5539 98.54 10889 13172 2 918.55464 460.2842 Olfactory receptor 5A2 OS=Homo sapiens OX=9606 GN=OR5A2 PE=2 SV=1 8.59 2937.8 - 506449 - - - 0.8557 - 1.529 0.356 - 157.3 1 1 0 0.0008 9 0 0 0 2.19E+07 2.23E+05 - - - 2.8986 0.9549 230117_WJC_METTL3_WT_vs_EV_F02.13175.13175.2 2.67 14-May K.VLTISTLR[166.11].L "sp|Q12830|BPTF_HUMAN,tr|F5GXF5|F5GXF5_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN,tr|A0A0A0MR81|A0A0A0MR81_HUMAN" 6 911.5679 0.82 10892 13175 2 911.567722 456.7912 Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3 9.72 2938.2 - 220497 - - - -0.2359 - 1.022 0.13 - 43.5 4 2 0 -0.0002 8 0 0 0 6.32E+07 7.70E+07 - - - -0.2022 0.9393 230117_WJC_METTL3_WT_vs_EV_F02.13179.13179.2 0.00324 14-Sep E.ILNPLVSK.A "sp|Q6NUP7|PP4R4_HUMAN,sp|Q9BSC4|NOL10_HUMAN,tr|G3V431|G3V431_HUMAN" 3 882.5539 1.06 10894 13179 2 882.553628 442.2842 Serine\threonine-protein phosphatase 4 regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PPP4R4 PE=1 SV=1 8.75 2938.7 - 1.32E+06 - - - -0.2561 - 1.467 0.419 - 191.8 1 1 0 -0.0002 8 0 0 0 1.01E+08 9.53E+07 - - - 3.2914 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.13187.13187.2 0.00932 16-Jul K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 28.52 10899 13187 2 1014.535955 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 2939.6 - 576882 - - - 1.3602 - 1.482 0.233 - 91.7 1 2 0 0.0014 9 0 0 0 1.70E+07 5.96E+05 - - - 1.8996 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.13189.13189.2 0.0893 16-Aug R.ILVLNGGYR.G "sp|O60870|KIN17_HUMAN,tr|S4R357|S4R357_HUMAN" 2 1003.5815 1.83 10901 13189 2 1003.58256 502.798 DNA\RNA-binding protein KIN17 OS=Homo sapiens OX=9606 GN=KIN PE=1 SV=2 8.75 2939.9 - 567078 - - - 1.0911 - 1.625 0.223 - 191.2 1 2 0 0.0011 9 0 0 0 2.09E+07 1.14E+07 - - - 2.0923 0.9937 230117_WJC_METTL3_WT_vs_EV_F02.13190.13190.2 0.162 14-Jun K.VLTISTLR.L "sp|Q12830|BPTF_HUMAN,tr|F5GXF5|F5GXF5_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN,tr|A0A0A0MR81|A0A0A0MR81_HUMAN" 6 901.5597 0.82 10902 13190 2 901.560599 451.7871 Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3 9.72 2940 - 378362 - - - 1.0338 - 1.228 0.157 - 79.3 1 2 0 0.0009 8 0 0 0 6.29E+07 7.67E+07 - - - 0.8197 0.9782 230117_WJC_METTL3_WT_vs_EV_F02.13194.13194.2 1.32 14-Aug K.LIGQLNLK.D "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 897.5648 1.59 10904 13194 2 897.565649 449.7897 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 2940.6 - 510860 - - - 0.9983 - 1.35 0.002 - 114 1 2 0 0.0009 8 0 0 0 1.69E+07 1.06E+07 - - - -0.0394 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.13203.13203.2 0.0866 14-May K.VLPITVPK.S sp|Q9ULW0|TPX2_HUMAN 1 865.5637 2.04 10911 13203 2 865.564119 433.7891 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.72 2941.6 - 1.85E+06 - - - 0.4956 - 1.142 0.382 - 74.3 1 2 0 0.0004 8 0 0 0 6.86E+07 3.36E+07 - - - 2.2628 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.13214.13214.2 0.23 14-Sep K.INELLLAK[136.11].E "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 920.5786 2.47 10918 13214 2 920.580081 461.2966 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 6 2942.9 - 620274 - - - 1.5892 - 1.554 0.217 - 172.1 1 2 0 0.0015 8 0 0 0 6.13E+07 2.48E+07 - - - 1.9728 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.13226.13226.2 1.08 14-Aug K.VVNPLFEK[136.11].R "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 952.5473 0.77 10926 13226 2 952.548799 477.2809 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.97 2944.4 - 1.10E+06 - - - 1.5548 - 1.644 0.334 - 164.2 1 2 0 0.0015 8 0 0 0 1.09E+08 1.42E+08 - - - 3.0068 0.9927 230117_WJC_METTL3_WT_vs_EV_F02.13232.13232.2 0.264 14-Jun R.LFVGSIPK[136.11].S "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 867.5309 0.91 10930 13232 2 867.531038 434.7727 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.75 2945.1 - 719326 - - - 0.113 - 1.281 0.155 - 91.5 1 2 0 0.0001 8 0 0 0 1.47E+09 1.62E+09 - - - 0.9327 0.9878 230117_WJC_METTL3_WT_vs_EV_F02.13233.13233.2 2.34 16-Jul K.LLSGNLALR[166.11].S sp|Q53S58|TM177_HUMAN 1 965.5897 0.99 10931 13233 2 965.590357 483.8021 Transmembrane protein 177 OS=Homo sapiens OX=9606 GN=TMEM177 PE=1 SV=1 9.75 2945.2 - 294531 - - - 0.6442 - 1.441 0.071 - 115.1 3 2 0 0.0006 9 0 0 0 9.31E+06 9.36E+06 - - - 0.409 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.13238.13238.2 0.119 12-Aug R.NLPMHLR.R "sp|Q9P2E3|ZNFX1_HUMAN,tr|Q5JXR6|Q5JXR6_HUMAN,tr|Q5JXR7|Q5JXR7_HUMAN,tr|Q5JXR5|Q5JXR5_HUMAN" 4 879.4749 309.42 10934 13238 2 879.475875 440.7447 NFX1-type zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=ZNFX1 PE=2 SV=2 9.76 2945.8 - 2.86E+06 - - - 1.1177 - 1.65 0.307 - 241.8 1 2 0 0.001 7 0 0 0 2.07E+08 6.68E+05 - - - 2.8949 0.9926 230117_WJC_METTL3_WT_vs_EV_F02.13248.13248.2 0.184 14-Sep K.ALELTGLK[136.11].V "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 851.5208 0.54 10940 13248 2 851.521812 426.7677 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6.05 2947 - 4.79E+06 - - - 1.2249 - 1.719 0.002 - 250 1 2 0 0.001 8 0 0 0 1.14E+08 2.11E+08 - - - 0.6893 0.962 230117_WJC_METTL3_WT_vs_EV_F02.13252.13252.2 3.68 12-May K.FIPLYSK[136.11].V "sp|Q14694|UBP10_HUMAN,tr|J3KT19|J3KT19_HUMAN,tr|H3BVF1|H3BVF1_HUMAN" 3 874.5044 1.15 10944 13252 2 874.506607 438.2595 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.59 2947.5 - 208443 - - - 2.534 - 0.964 0.118 - 49.2 1 2 0 0.0022 7 0 0 0 1.10E+08 9.56E+07 - - - -0.2043 0.9386 230117_WJC_METTL3_WT_vs_EV_F02.13256.13256.2 3.42 16-Oct H.VVVLVATVR[166.11].A "sp|P11586|C1TC_HUMAN,sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 8 964.6309 2.81 10946 13256 2 964.632486 483.3227 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.72 2948 - 278598 - - - 1.6732 - 2.116 0.21 - 247.2 2 1 0 0.0016 9 0 0 0 2.65E+07 9.41E+06 - - - 2.6255 0.9851 230117_WJC_METTL3_WT_vs_EV_F02.13260.13260.2 1.01 12-Jul K.TIADIIR.T "sp|P49368|TCPG_HUMAN,sp|Q16878|CDO1_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 800.4756 10.76 10948 13260 2 800.476472 401.2451 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.5 2948.5 - 2.16E+06 - - - 1.0856 - 1.158 0.095 - 202.6 1 2 0 0.0009 7 0 0 0 2.08E+09 1.94E+08 - - - 0.2072 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.13278.13278.2 0.000662 12-Jul K.YGVDLIR.Y sp|Q6UXN9|WDR82_HUMAN 1 834.46 1.39 10957 13278 2 834.461739 418.2373 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 5.84 2950.8 - 1.14E+06 - - - 2.1403 - 1.56 0.169 - 167.7 1 2 0 0.0018 7 0 0 0 8.14E+07 5.84E+07 - - - 1.6977 0.9741 230117_WJC_METTL3_WT_vs_EV_F02.13280.13280.2 1.02 12-Aug R.SVTLLIK.G sp|P40227|TCPZ_HUMAN 1 772.5058 8.13 10958 13280 2 772.506946 387.2602 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 8.47 2951 - 1.52E+06 - - - 1.4304 - 1.178 0.037 - 202.9 1 2 0 0.0011 7 0 0 0 3.40E+09 4.18E+08 - - - -0.167 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.13296.13296.2 1.04 12-Jul K.SVIISIK[136.11].G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 766.5044 1.19 10966 13296 2 766.505338 384.2595 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2953.1 - 771027 - - - 1.2355 - 1.325 0.186 - 192.6 1 2 0 0.0009 7 0 0 0 2.03E+08 1.71E+08 - - - 1.3062 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.13297.13297.2 0.0567 14-Jul R.IFTNLYGR.H "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 4 982.5236 1.16 10967 13297 2 982.524683 492.2691 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.75 2953.3 - 546435 - - - 1.086 - 1.443 0.235 - 107 1 2 0 0.0011 8 0 0 0 6.79E+07 5.84E+07 - - - 1.8824 0.9947 230117_WJC_METTL3_WT_vs_EV_F02.13304.13304.2 0.582 12-Jul K.SVIISIK.G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 758.4902 1.18 10970 13304 2 758.491372 380.2524 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2954.2 - 1.24E+06 - - - 1.557 - 1.276 0.153 - 192.3 1 2 0 0.0012 7 0 0 0 2.03E+08 1.71E+08 - - - 0.943 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.13312.13312.2 0.00582 14-Aug K.VVNPLFEK.R "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 944.5331 0.75 10977 13312 2 944.533594 473.2738 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.97 2955 - 1.90E+06 - - - 0.504 - 1.652 0.338 - 195.4 1 2 0 0.0005 8 0 0 0 1.07E+08 1.42E+08 - - - 3.0513 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.13322.13322.2 4.23 18-Nov R.LLAEPVPGIK[136.11].A "sp|P61088|UBE2N_HUMAN,sp|Q5JXB2|UE2NL_HUMAN,tr|F8VZ29|F8VZ29_HUMAN,tr|F8VSD4|F8VSD4_HUMAN,tr|F8VV71|F8VV71_HUMAN" 5 1043.647 1.65 10980 13322 2 1043.648494 522.8308 Ubiquitin-conjugating enzyme E2 N OS=Homo sapiens OX=9606 GN=UBE2N PE=1 SV=1 6 2956.4 - 1.04E+06 - - - 1.4009 - 1.828 0.17 - 298.2 1 2 0 0.0015 10 0 0 0 1.30E+08 7.88E+07 - - - 1.9799 0.9811 230117_WJC_METTL3_WT_vs_EV_F02.13324.13324.2 0.476 14-Jul K.NLILAGVK.G "sp|Q9UBE0|SAE1_HUMAN,tr|B3KNJ4|B3KNJ4_HUMAN,tr|M0QZS6|M0QZS6_HUMAN,tr|A0A590UKC5|A0A590UKC5_HUMAN,tr|M0QX65|M0QX65_HUMAN,tr|A0A590UKA0|A0A590UKA0_HUMAN,tr|A0A590UK93|A0A590UK93_HUMAN" 7 826.5276 4.63 10982 13324 2 826.527591 414.2711 SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1 PE=1 SV=1 8.75 2956.7 - 902628 - - - -0.0581 - 1.342 0.053 - 142.3 1 2 0 0 8 0 0 0 5.06E+07 1.09E+07 - - - 0.3196 0.9944 230117_WJC_METTL3_WT_vs_EV_F02.13326.13326.2 0.755 12-Jul R.IGLLDPR[166.11].W "sp|Q15459|SF3A1_HUMAN,tr|H7C1L2|H7C1L2_HUMAN" 2 792.4733 1.39 10983 13326 2 792.473891 397.2439 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 5.84 2956.9 - 2.41E+06 - - - 0.7357 - 1.36 0.145 - 96.3 2 2 0 0.0006 7 0 0 0 3.39E+08 2.44E+08 - - - 0.9516 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.13329.13329.2 0.416 12-Jul K.IVVLLQR.L "sp|Q06323|PSME1_HUMAN,tr|H0YLU2|H0YLU2_HUMAN" 2 839.5593 1.45 10985 13329 2 839.560809 420.7869 Proteasome activator complex subunit 1 OS=Homo sapiens OX=9606 GN=PSME1 PE=1 SV=1 9.75 2957.2 - 527971 - - - 1.8295 - 1.435 0.182 - 112.4 1 2 0 0.0015 7 0 0 0 3.53E+07 2.44E+07 - - - 1.5291 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.13335.13335.2 0.625 14-Jul R.ILEVLPGR.R sp|Q9UI43|MRM2_HUMAN 1 895.5491 2.83 10987 13335 2 895.55133 448.7818 "rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1" 6 2958.1 - 376756 - - - 2.4879 - 1.446 0.22 - 115 1 2 0 0.0022 8 0 0 0 6.28E+07 2.22E+07 - - - 1.7775 1 230117_WJC_METTL3_WT_vs_EV_F02.13339.13339.2 5.60E-08 24-Oct R.TTPSYVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1486.694 13.51 10989 13339 2 1486.70066 744.3543 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2958.6 - 235633 - - - 4.4871 - 2.364 0.563 - 284 1 2 0 0.0067 13 0 0 0 6.50E+07 4.81E+06 - - - 5.4053 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.13340.13340.2 0.0657 14-Aug R.IFTNLYGR[166.11].H "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 4 992.5319 1.16 10990 13340 2 992.532897 497.2732 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.75 2958.7 - 1.62E+06 - - - 1.0186 - 1.474 0.23 - 179.2 1 2 0 0.001 8 0 0 0 6.79E+07 5.88E+07 - - - 1.9096 0.9932 230117_WJC_METTL3_WT_vs_EV_F02.13345.13345.2 0.271 12-Jul K.ELVVLPR[166.11].E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 834.5203 0.5 10993 13345 2 834.519173 418.2674 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2959.3 - 1.56E+06 - - - -1.3013 - 1.395 0.216 - 176.7 1 2 0 -0.0011 7 0 0 0 1.81E+08 3.64E+08 - - - 1.6908 0.9953 230117_WJC_METTL3_WT_vs_EV_F02.13347.13347.2 1.9 14-Jul K.LVALNLDR.L "sp|Q9Y3D3|RT16_HUMAN,tr|A6ND22|A6ND22_HUMAN" 2 912.5393 1.13 10994 13347 2 912.539039 457.2769 "28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1" 5.84 2959.5 - 1.18E+06 - - - -0.2488 - 1.546 0.146 - 132.1 1 2 0 -0.0002 8 0 0 0 8.12E+07 7.18E+07 - - - 1.4332 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.13349.13349.2 0.000347 16-Sep K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 451.95 10995 13349 2 1059.557143 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2959.7 - 549237 - - - 1.0429 - 1.702 0.396 - 299.7 1 2 0 0.0011 9 0 0 0 2.39E+07 5.30E+04 - - - 3.504 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.13355.13355.2 0.0753 14-Jul R.ILEVLPGR[166.11].R sp|Q9UI43|MRM2_HUMAN 1 905.5574 2.8 10997 13355 2 905.560299 453.786 "rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1" 6 2960.6 - 462970 - - - 3.2323 - 1.564 0.285 - 127.9 1 2 0 0.0029 8 0 0 0 6.20E+07 2.21E+07 - - - 2.494 0.9954 230117_WJC_METTL3_WT_vs_EV_F02.13361.13361.2 11.3 12-Aug K.LLDIVAR[166.11].S sp|Q12931|TRAP1_HUMAN 1 808.5046 1.94 11000 13361 2 808.50577 405.2596 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.84 2961.4 - 3.09E+06 - - - 1.436 - 1.792 0.021 - 207.3 1 2 0 0.0012 7 0 0 0 2.99E+08 1.54E+08 - - - 1.0441 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.13369.13369.2 0.567 12-Jun K.ELVVLPR.E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 824.512 0.5 11002 13369 2 824.513351 413.2633 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2962.5 - 1.36E+06 - - - 1.6519 - 1.395 0.198 - 206 1 2 0 0.0014 7 0 0 0 1.82E+08 3.64E+08 - - - 1.5578 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.13376.13376.2 0.599 14-Aug K.LVALNLDR[166.11].L "sp|Q9Y3D3|RT16_HUMAN,tr|A6ND22|A6ND22_HUMAN" 2 922.5475 1.15 11006 13376 2 922.54808 462.281 "28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1" 5.84 2963.4 - 2.34E+06 - - - 0.5897 - 1.365 0.247 - 211.2 1 2 0 0.0005 8 0 0 0 8.24E+07 7.18E+07 - - - 1.8036 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.13378.13378.2 0.0256 14-Jul K.VMMVALGR.S sp|Q9UKD2|MRT4_HUMAN 1 875.4721 1.38 11007 13378 2 875.473549 438.7433 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 9.72 2963.6 - 1.15E+06 - - - 1.6391 - 1.363 0.317 - 108.2 1 2 0 0.0014 8 0 0 0 6.03E+07 4.36E+07 - - - 2.3159 0.9935 230117_WJC_METTL3_WT_vs_EV_F02.13380.13380.2 0.0272 18-Oct R.VAQLEQVYIR[166.11].G sp|P62318|SMD3_HUMAN 1 1227.6851 0.95 11009 13380 2 1227.688653 614.8498 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.97 2963.9 - 181679 - - - 2.9006 - 1.893 0.05 - 286.2 1 2 0 0.0036 10 0 0 0 4.58E+06 4.82E+06 - - - 1.1905 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.13381.13381.2 1.44E-05 24-Oct R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 13.51 11010 13381 2 1496.707712 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2964 - 86662.9 - - - 3.6433 - 1.853 0.501 - 271.6 1 2 0 0.0055 13 0 0 0 6.50E+07 4.81E+06 - - - 4.3227 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.13385.13385.2 0.027 12-Jul K.YVIYIER.V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 954.5175 0.82 11011 13385 2 954.518221 478.266 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 6 2964.6 - 2.26E+06 - - - 0.7889 - 1.439 0.211 - 218.3 1 2 0 0.0008 7 0 0 0 9.09E+08 1.10E+09 - - - 1.7524 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.13387.13387.2 0.805 14-Aug R.LGALALPR[166.11].G "sp|Q6SPF0|SAMD1_HUMAN,tr|E9PIW9|E9PIW9_HUMAN" 2 819.5206 2.09 11012 13387 2 819.521675 410.7676 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.75 2964.8 - 878357 - - - 1.3203 - 1.989 0.181 - 232.4 1 2 0 0.0011 8 0 0 0 2.05E+08 9.80E+07 - - - 2.4514 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.13389.13389.2 0.023 14-Jul K.VMMVALGR[166.11].S sp|Q9UKD2|MRT4_HUMAN 1 885.4804 1.38 11013 13389 2 885.481018 443.7475 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 9.72 2965 - 1.62E+06 - - - 0.716 - 1.432 0.353 - 204.7 1 2 0 0.0006 8 0 0 0 6.02E+07 4.35E+07 - - - 2.731 0.9839 230117_WJC_METTL3_WT_vs_EV_F02.13391.13391.2 1.19 16-Apr K.ESYSIYVYK[136.11].V "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q6DN03|H2B2C_HUMAN,sp|P23527|H2B1O_HUMAN,sp|Q6DRA6|H2B2D_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN" 7 1158.5688 0.73 11015 13391 2 1158.569702 580.2917 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.1 2965.3 - 180515 - - - 0.7432 - 0.936 0.201 - 39 2 2 0 0.0009 9 0 0 0 1.86E+06 2.54E+06 - - - 0.1995 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.13398.13398.2 0.00108 24-Aug K.VIDPATATSVDLR.D sp|P50991|TCPD_HUMAN 1 1356.7249 999 11019 13398 2 1356.728556 679.3697 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 2966.2 - 184419 - - - 2.6984 - 1.615 0.37 - 101.6 1 2 0 0.0037 13 0 0 0 9.47E+06 0.00E+00 - - - 3.0029 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.13402.13402.2 0.0117 12-Jul R.VVFQEFR[166.11].Q sp|P35579|MYH9_HUMAN 1 933.4948 0.9 11021 13402 2 933.496949 467.7547 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2966.7 - 429806 - - - 2.3321 - 1.366 0.34 - 200.4 1 2 0 0.0022 7 0 0 0 2.31E+08 2.56E+08 - - - 2.5398 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.13406.13406.2 0.0905 16-Aug R.ILVGTNLVR.L sp|Q96QK1|VPS35_HUMAN 1 983.6128 1.91 11024 13406 2 983.614883 492.8137 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 9.75 2967.1 - 1.71E+06 - - - 2.1533 - 1.647 0.163 - 158.4 1 2 0 0.0021 9 0 0 0 7.47E+07 3.91E+07 - - - 1.6878 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.13407.13407.2 1.8 16-Jul R.ILVGTNLVR[166.11].L sp|Q96QK1|VPS35_HUMAN 1 993.621 1.91 11025 13407 2 993.623077 497.8178 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 9.75 2967.2 - 991937 - - - 2.0551 - 1.388 0.222 - 117 1 2 0 0.002 9 0 0 0 7.47E+07 3.91E+07 - - - 1.6286 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.13415.13415.2 0.00407 22-Jul R.LLSASPVDAAIR[166.11].V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1221.6957 5.67 11028 13415 2 1221.697859 611.8551 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 5.84 2968.4 - 145708 - - - 1.8024 - 1.633 0.432 - 92.3 1 2 0 0.0022 12 0 0 0 7.75E+06 1.37E+06 - - - 3.5214 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.13430.13430.2 0.408 14-Aug R.LLSTYLER[166.11].Y "sp|Q12769|NU160_HUMAN,tr|G3V198|G3V198_HUMAN" 2 1003.5578 1.18 11034 13430 2 1003.560468 502.7862 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 6 2970.4 - 1.31E+06 - - - 2.6924 - 1.618 0.287 - 185.6 1 2 0 0.0027 8 0 0 0 6.13E+07 5.22E+07 - - - 2.6112 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.13440.13440.2 0.0355 12-Jul R.YLLAMER.H "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 894.4633 3.15 11040 13440 2 894.464762 448.2389 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 2971.5 - 587316 - - - 1.6077 - 1.531 0.188 - 177.8 1 2 0 0.0014 7 0 0 0 3.89E+07 1.23E+07 - - - 1.7787 0.996 230117_WJC_METTL3_WT_vs_EV_F02.13443.13443.2 1.06 12-Jun K.IFTFAEK[136.11].Y "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 4 862.468 0.12 11042 13443 2 862.468545 432.2413 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 6 2971.8 - 836107 - - - 0.6261 - 1.303 0.183 - 74.5 1 2 0 0.0005 7 0 0 0 6.35E+07 5.16E+08 - - - 1.2311 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.13444.13444.2 0.237 12-Jul R.EALGLLR.A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 770.465 1.08 11043 13444 2 770.466546 386.2398 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2971.9 - 1.36E+06 - - - 1.9573 - 1.607 0.155 - 180.4 1 2 0 0.0015 7 0 0 0 2.40E+08 2.23E+08 - - - 1.6884 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.13445.13445.2 0.00114 16-Aug R.MPVGSPLLR[166.11].D "sp|Q9NVS2|RT18A_HUMAN,tr|Q5QPA5|Q5QPA5_HUMAN" 2 978.556 1.47 11044 13445 2 978.557318 490.2853 "39S ribosomal protein S18a, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18A PE=1 SV=1" 9.5 2972.1 - 401758 - - - 1.3551 - 1.64 0.284 - 147.2 1 2 0 0.0013 9 0 0 0 9.45E+07 6.43E+07 - - - 2.5694 0.997 230117_WJC_METTL3_WT_vs_EV_F02.13449.13449.2 0.171 12-Jun R.EALGLLR[166.11].A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 780.4733 1.08 11046 13449 2 780.474333 391.2439 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2972.5 - 2.53E+06 - - - 1.3133 - 1.384 0.178 - 137.6 1 2 0 0.001 7 0 0 0 2.40E+08 2.23E+08 - - - 1.3851 0.8703 230117_WJC_METTL3_WT_vs_EV_F02.13455.13455.2 0.0186 12-Jul P.FPAALLR.V "sp|Q9H0D2|ZN541_HUMAN,sp|Q9UJV9|DDX41_HUMAN,tr|H7BXG6|H7BXG6_HUMAN,tr|M0R167|M0R167_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|A0A075B6F0|A0A075B6F0_HUMAN,tr|H0Y8L8|H0Y8L8_HUMAN" 7 786.4752 0.96 11049 13455 2 786.476365 394.2449 Zinc finger protein 541 OS=Homo sapiens OX=9606 GN=ZNF541 PE=1 SV=3 9.75 2973.2 - 668924 - - - 1.4698 - 1.363 0.238 - 135.2 1 1 0 0.0012 7 0 0 0 4.29E+08 4.46E+08 - - - 1.7798 0.9798 230117_WJC_METTL3_WT_vs_EV_F02.13458.13458.2 0.021 16-Aug K.LLNYAPLEK.- sp|P62875|RPAB5_HUMAN 1 1059.5964 1.2 11050 13458 2 1059.604122 530.8055 "DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1" 6 2973.6 - 425900 - - - 7.2433 - 1.516 0.347 - 179.5 1 2 0 0.0077 9 0 0 0 2.16E+07 1.79E+07 - - - 2.8053 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.13465.13465.2 0.0198 20-Jul K.QAGVFEPTIVK.V "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1187.655 53.82 11055 13465 2 1187.65843 594.8348 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2974.5 - 181986 - - - 2.8678 - 1.482 0.343 - 155.6 1 2 0 0.0034 11 0 0 0 1.79E+07 3.32E+05 - - - 2.6375 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.13468.13468.2 0.0472 16-Sep R.IVDPEIALK.L "sp|P33240|CSTF2_HUMAN,tr|A0A0A0MT56|A0A0A0MT56_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 996.5855 3.22 11056 13468 2 996.587183 499.3001 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.37 2974.9 - 1.61E+06 - - - 1.6406 - 1.829 0.333 - 171.7 1 2 0 0.0016 9 0 0 0 1.03E+09 3.20E+08 - - - 3.2468 0.996 230117_WJC_METTL3_WT_vs_EV_F02.13469.13469.2 0.0707 12-Jul R.LMFAVEK[136.11].S sp|Q5SWX8|ODR4_HUMAN 1 844.4608 0.9 11057 13469 2 844.460836 423.2377 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 6 2975 - 692185 - - - 0.0296 - 1.407 0.178 - 111.9 1 2 0 0 7 0 0 0 5.32E+07 5.94E+07 - - - 1.4376 0.9755 230117_WJC_METTL3_WT_vs_EV_F02.13470.13470.2 0.00406 12-Oct K.PSVYFIK[136.11].F "sp|Q99865|SPI2A_HUMAN,sp|Q56A73|SPIN4_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 9 860.4887 0.5 11058 13470 2 860.489636 431.2516 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 9.01 2975 - 2.05E+06 - - - 1.0401 - 1.965 0.387 - 328.3 1 1 0 0.0009 7 0 0 0 3.09E+08 6.19E+08 - - - 4.0394 0.9751 230117_WJC_METTL3_WT_vs_EV_F02.13471.13471.2 0.44 16-Jul R.IVDPEIALK[136.11].L "sp|P33240|CSTF2_HUMAN,tr|A0A0A0MT56|A0A0A0MT56_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 1004.5997 2.86 11059 13471 2 1004.598314 503.3072 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.37 2975.1 - 804852 - - - -1.4274 - 1.118 0.183 - 72.6 1 2 0 -0.0014 9 0 0 0 8.83E+08 3.08E+08 - - - 0.7149 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.13482.13482.2 0.00684 14-Jul K.MMMVLGAK.W "sp|Q14839|CHD4_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|F5H6N4|F5H6N4_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 17 879.438 1.19 11066 13482 2 879.43961 440.7263 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.5 2976.4 - 523560 - - - 1.7886 - 1.311 0.268 - 149.2 1 2 0 0.0016 8 0 0 0 2.50E+07 2.11E+07 - - - 1.8366 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.13492.13492.2 0.0358 12-Jul R.VVFQEFR.Q sp|P35579|MYH9_HUMAN 1 923.4865 0.9 11071 13492 2 923.487472 462.7505 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2977.6 - 3.76E+06 - - - 1.0504 - 1.452 0.376 - 236.9 1 2 0 0.001 7 0 0 0 2.31E+08 2.56E+08 - - - 2.9995 0.9904 230117_WJC_METTL3_WT_vs_EV_F02.13494.13494.2 0.579 12-Jul K.QLLYLEK.Y "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 3 905.5222 0.92 11072 13494 2 905.522942 453.7684 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 6 2977.8 - 1.25E+06 - - - 0.7984 - 1.178 0.134 - 165.3 1 2 0 0.0007 7 0 0 0 7.64E+07 8.30E+07 - - - 0.5496 0.9779 230117_WJC_METTL3_WT_vs_EV_F02.13511.13511.2 2.61 20-Jul R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 999 11078 13511 2 1068.659363 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 2980.1 - 339423 - - - 4.7415 - 1.453 0.171 - 80.2 2 2 0 0.0051 11 0 0 0 6.09E+07 0.00E+00 - - - 1.1787 0.965 230117_WJC_METTL3_WT_vs_EV_F02.13513.13513.2 0.000418 12-Sep K.PSVYFIK.F "sp|Q99865|SPI2A_HUMAN,sp|Q56A73|SPIN4_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 9 852.4745 0.5 11079 13513 2 852.474374 427.2445 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 9.01 2980.3 - 7.48E+06 - - - -0.1959 - 2.038 0.408 - 276.4 1 1 0 -0.0002 7 0 0 0 3.09E+08 6.19E+08 - - - 4.3103 0.9922 230117_WJC_METTL3_WT_vs_EV_F02.13515.13515.2 1.18 14-Aug K.IADFGLAR[166.11].L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 871.4791 1.99 11080 13515 2 871.478839 436.7468 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2980.5 - 1.84E+06 - - - -0.3247 - 1.355 0.151 - 179.8 1 2 0 -0.0003 8 0 0 0 1.03E+09 5.21E+08 - - - 1.0724 0.9426 230117_WJC_METTL3_WT_vs_EV_F02.13529.13529.2 0.00776 16-Aug K.PLYVALAQR[166.11].K "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PIK9|A0A6I8PIK9_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 25 1039.6054 1.14 11087 13529 2 1039.605208 520.81 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.18 2982.3 - 362050 - - - -0.1703 - 1.677 0.375 - 227.2 1 1 0 -0.0002 9 0 0 0 4.50E+08 3.95E+08 - - - 3.3064 0.9349 230117_WJC_METTL3_WT_vs_EV_F02.13532.13532.2 0.892 12-May R.AFLGELK.T sp|P78527|PRKDC_HUMAN 1 776.4432 1.02 11088 13532 2 776.442462 389.2289 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6.05 2982.7 - 2.85E+06 - - - -1.002 - 1.17 0.061 - 107.4 2 2 0 -0.0008 7 0 0 0 1.25E+08 1.23E+08 - - - -0.1457 0.9645 230117_WJC_METTL3_WT_vs_EV_F02.13544.13544.2 1.36 14-Aug K.IADFGLAR.L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 861.4709 1.98 11094 13544 2 861.467034 431.7427 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2984.2 - 2.24E+07 - - - -4.432 - 1.708 0.175 - 170.1 1 2 0 -0.0038 8 0 0 0 1.03E+09 5.20E+08 - - - 1.9469 0.9906 230117_WJC_METTL3_WT_vs_EV_F02.13556.13556.2 0.0277 12-Jul R.YFEPLVK.K "sp|Q7L590|MCM10_HUMAN,tr|Q5T670|Q5T670_HUMAN" 2 894.4851 3.59 11101 13556 2 894.484236 448.2498 Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2 6 2985.7 - 487591 - - - -0.9715 - 1.314 0.181 - 130.6 1 2 0 -0.0009 7 0 0 0 1.13E+08 3.16E+07 - - - 1.2428 0.9564 230117_WJC_METTL3_WT_vs_EV_F02.13562.13562.2 0.492 14-Jul K.LLQPLVPR[166.11].Y sp|Q8N8A6|DDX51_HUMAN 1 944.6047 1.05 11103 13562 2 944.603478 473.3096 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2986.5 - 781279 - - - -1.2481 - 1.14 0.108 - 92.8 1 2 0 -0.0012 8 0 0 0 1.12E+08 1.06E+08 - - - 0.2335 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.13566.13566.2 2.98 14-Nov K.LAVEAVLR[166.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 879.5417 7.24 11105 13566 2 879.541131 440.7781 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 2986.9 - 3.34E+06 - - - -0.6719 - 1.8 0.129 - 541.2 1 2 0 -0.0006 8 0 0 0 6.56E+09 9.06E+08 - - - 1.7663 0.997 230117_WJC_METTL3_WT_vs_EV_F02.13571.13571.2 7.29 14-Aug K.LAVEAVLR.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 869.5335 7.21 11108 13571 2 869.532355 435.774 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 2987.4 - 1.97E+07 - - - -1.2616 - 1.82 0.218 - 232.9 1 2 0 -0.0011 8 0 0 0 6.59E+09 9.14E+08 - - - 2.4569 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.13573.13573.2 0.505 14-Aug K.LLQLVEDR.G "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 984.5604 0.55 11110 13573 2 984.559545 493.2875 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 2987.5 - 5.26E+06 - - - -0.8633 - 1.561 0.235 - 177.9 1 2 0 -0.0008 8 0 0 0 1.69E+08 3.09E+08 - - - 2.1195 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.13588.13588.2 0.0159 14-Jul K.IINDLLAR.S "sp|P51530|DNA2_HUMAN,tr|F8VR31|F8VR31_HUMAN,tr|H0Y455|H0Y455_HUMAN" 3 926.5549 3.09 11115 13588 2 926.553155 464.2847 DNA replication ATP-dependent helicase\nuclease DNA2 OS=Homo sapiens OX=9606 GN=DNA2 PE=1 SV=3 5.84 2989.5 - 351344 - - - -1.9006 - 1.386 0.349 - 121.3 1 2 0 -0.0018 8 0 0 0 3.12E+07 1.01E+07 - - - 2.6026 0.9882 230117_WJC_METTL3_WT_vs_EV_F02.13592.13592.2 0.414 12-Jul K.ILEVDLK[136.11].N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 836.5099 0.85 11117 13592 2 836.508699 419.2622 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2989.9 - 2.39E+06 - - - -1.3999 - 1.495 0.13 - 124.2 1 2 0 -0.0012 7 0 0 0 2.97E+08 3.50E+08 - - - 1.275 0.9894 230117_WJC_METTL3_WT_vs_EV_F02.13608.13608.2 0.138 14-Aug K.LLQPLVPR.Y sp|Q8N8A6|DDX51_HUMAN 1 934.5964 1.05 11121 13608 2 934.594599 468.3055 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2992.4 - 2.14E+06 - - - -1.9131 - 1.494 0.188 - 228.8 1 2 0 -0.0018 8 0 0 0 1.12E+08 1.06E+08 - - - 1.6398 0.9751 230117_WJC_METTL3_WT_vs_EV_F02.13609.13609.2 5.55 12-Jun R.IINTFLK.T "sp|Q86Y56|DAAF5_HUMAN,tr|H0Y650|H0Y650_HUMAN,tr|E9PGY2|E9PGY2_HUMAN" 3 847.5167 10.47 11122 13609 2 847.515287 424.7656 Dynein axonemal assembly factor 5 OS=Homo sapiens OX=9606 GN=DNAAF5 PE=1 SV=4 8.75 2992.5 - 1.15E+06 - - - -1.7144 - 1.256 0.147 - 81.3 1 2 0 -0.0015 7 0 0 0 4.17E+07 3.98E+06 - - - 0.8485 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.13616.13616.2 0.0552 14-Jul K.ILDVMYSR[166.11].L sp|P78527|PRKDC_HUMAN 1 1005.5193 0.98 11124 13616 2 1005.520039 503.7669 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2993.4 - 346452 - - - 0.7628 - 1.422 0.307 - 98.4 1 2 0 0.0008 8 0 0 0 6.71E+07 6.84E+07 - - - 2.3701 0.9964 230117_WJC_METTL3_WT_vs_EV_F02.13618.13618.2 0.429 12-Jun R.YLDELMK.L "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 910.447 1.7 11125 13618 2 910.44759 456.2308 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 2993.6 - 1.23E+06 - - - 0.6425 - 1.15 0.249 - 95.7 1 2 0 0.0006 7 0 0 0 4.64E+07 2.73E+07 - - - 1.3228 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.13639.13639.2 0.257 12-Jun K.ILEVDLK.N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 828.4957 0.86 11134 13639 2 828.496134 415.2551 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2996.7 - 7.50E+06 - - - 0.5601 - 1.48 0.167 - 119.5 1 2 0 0.0005 7 0 0 0 3.02E+08 3.52E+08 - - - 1.5165 0.999 230117_WJC_METTL3_WT_vs_EV_F02.13643.13643.2 0.00209 18-Sep K.QQLLIGAYAK.A sp|Q99832|TCPH_HUMAN 1 1103.6339 15.54 11138 13643 2 1103.633473 552.8242 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.59 2997.1 - 272039 - - - -0.3824 - 1.572 0.378 - 192.1 1 2 0 -0.0004 10 0 0 0 7.43E+06 4.78E+05 - - - 3.0954 0.9815 230117_WJC_METTL3_WT_vs_EV_F02.13646.13646.2 0.211 14-Aug R.DLAPIGIR[166.11].V "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 863.5104 1.29 11139 13646 2 863.512264 432.7625 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 5.84 2997.5 - 1.44E+06 - - - 2.1332 - 1.443 0.001 - 190.6 1 2 0 0.0018 8 0 0 0 2.14E+08 1.66E+08 - - - 0.1538 0.9918 230117_WJC_METTL3_WT_vs_EV_F02.13653.13653.2 0.038 14-Aug R.DLAPIGIR.V "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 853.5022 1.05 11142 13653 2 853.504427 427.7584 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 5.84 2998.4 - 2.59E+06 - - - 2.6655 - 1.481 0.093 - 272.5 1 2 0 0.0023 8 0 0 0 2.37E+08 2.25E+08 - - - 0.9116 0.9926 230117_WJC_METTL3_WT_vs_EV_F02.13654.13654.2 6.83 12-May K.EAVLLLK[136.11].K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 792.52 0.75 11143 13654 2 792.521362 397.2673 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 2998.5 - 1.89E+06 - - - 1.6668 - 1.238 0.184 - 94.6 7 2 0 0.0013 7 0 0 0 6.86E+08 9.19E+08 - - - 0.6986 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.13655.13655.2 0.00147 12-Aug K.C[160.03]FLTAMR[166.11].E "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN" 3 907.4283 1.63 11144 13655 2 907.429449 454.7215 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 8.25 2998.6 - 706398 - - - 1.2122 - 1.527 0.357 - 231.6 1 2 0 0.0011 7 0 0 0 3.38E+07 2.07E+07 - - - 3.0187 0.9874 230117_WJC_METTL3_WT_vs_EV_F02.13665.13665.2 0.771 12-May K.VLEILGK.K "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 10 770.4902 2.42 11150 13665 2 770.491517 386.2524 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.97 2999.9 - 584777 - - - 1.721 - 1.319 0.15 - 94.9 35 2 0 0.0013 7 0 0 0 5.22E+07 2.16E+07 - - - 0.336 0.9938 230117_WJC_METTL3_WT_vs_EV_F02.13667.13667.2 0.509 12-Jun K.EAVLLLK.K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 784.5058 0.75 11152 13667 2 784.506975 393.2602 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 3000 - 2.15E+06 - - - 1.4455 - 1.303 0.127 - 176 1 2 0 0.0011 7 0 0 0 6.85E+08 9.19E+08 - - - 0.8173 0.9935 230117_WJC_METTL3_WT_vs_EV_F02.13669.13669.2 1.1 12-Jun K.VLEILGK[136.11].K "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 10 778.5044 2.52 11154 13669 2 778.505394 390.2595 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.97 3000.2 - 323240 - - - 1.2884 - 1.271 0.179 - 85.8 6 2 0 0.001 7 0 0 0 5.45E+07 2.16E+07 - - - 0.775 0.9876 230117_WJC_METTL3_WT_vs_EV_F02.13672.13672.2 0.126 20-May K.ITVTSEVPFSK.R "sp|P35268|RL22_HUMAN,tr|K7EKS7|K7EKS7_HUMAN,tr|K7ERI7|K7ERI7_HUMAN,tr|K7EMH1|K7EMH1_HUMAN,tr|K7ELC4|K7ELC4_HUMAN,tr|K7EP65|K7EP65_HUMAN,tr|K7EJT5|K7EJT5_HUMAN" 7 1206.6496 0.08 11155 13672 2 1206.654749 604.3321 60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2 6 3000.6 - 156179 - - - 4.2639 - 1.436 0.227 - 45.3 5 2 0 0.0051 11 0 0 0 2.47E+06 3.19E+07 - - - 1.3827 0.9055 230117_WJC_METTL3_WT_vs_EV_F02.13685.13685.2 0.397 14-Sep A.PSPGHILR.V "sp|Q63HM2|PCX4_HUMAN,tr|B5MC47|B5MC47_HUMAN,tr|H0YIY3|H0YIY3_HUMAN,tr|B6ZDM2|B6ZDM2_HUMAN" 4 875.4977 3.14 11163 13685 2 875.498694 438.7561 Pecanex-like protein 4 OS=Homo sapiens OX=9606 GN=PCNX4 PE=1 SV=4 10.18 3002.1 - 1.07E+06 - - - 1.0942 - 1.6 0.225 - 214.7 1 1 0 0.001 8 0 0 0 7.04E+07 2.24E+07 - - - 2.1201 0.9715 230117_WJC_METTL3_WT_vs_EV_F02.13696.13696.2 2.25 12-Jul R.MLIQQFR.Y "sp|Q7L5Y9|MAEA_HUMAN,tr|B4DVN3|B4DVN3_HUMAN,tr|B4DQT1|B4DQT1_HUMAN,tr|E7ESC7|E7ESC7_HUMAN" 4 934.5059 1.46 11170 13696 2 934.508769 468.2602 E3 ubiquitin-protein transferase MAEA OS=Homo sapiens OX=9606 GN=MAEA PE=1 SV=1 9.5 3003.4 - 326799 - - - 3.1161 - 1.124 0.108 - 139.7 1 2 0 0.0029 7 0 0 0 2.82E+07 1.93E+07 - - - 0.2082 0.9899 230117_WJC_METTL3_WT_vs_EV_F02.13703.13703.2 0.828 12-Jul R.LLQIIER[166.11].Y sp|P78527|PRKDC_HUMAN 1 893.5574 1.18 11172 13703 2 893.558195 447.786 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 3004.4 - 8.68E+06 - - - 0.921 - 1.402 0.051 - 187.9 1 2 0 0.0008 7 0 0 0 2.94E+08 2.50E+08 - - - 0.4881 0.99 230117_WJC_METTL3_WT_vs_EV_F02.13716.13716.2 0.57 14-Jun R.FIVLNPTR[166.11].F "sp|Q9NZW5|PALS2_HUMAN,tr|B8ZZG1|B8ZZG1_HUMAN" 2 968.5683 4.43 11180 13716 2 968.568185 485.2914 Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2 PE=1 SV=2 9.75 3006 - 561516 - - - -0.0898 - 1.305 0.145 - 124.5 2 2 0 -0.0001 8 0 0 0 7.63E+07 1.72E+07 - - - 0.7803 0.9829 230117_WJC_METTL3_WT_vs_EV_F02.13728.13728.2 0.893 16-Aug K.SLTMVALAK.L "sp|P83111|LACTB_HUMAN,tr|H0YNN5|H0YNN5_HUMAN" 2 932.5365 1.53 11189 13728 2 932.536256 467.2755 "Serine beta-lactamase-like protein LACTB, mitochondrial OS=Homo sapiens OX=9606 GN=LACTB PE=1 SV=2" 8.47 3007.5 - 196050 - - - -0.2499 - 1.241 0.108 - 130.6 1 2 0 -0.0002 9 0 0 0 7.49E+06 4.89E+06 - - - 0.4633 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.13749.13749.2 0.0219 14-Sep K.LALDYGIK.F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 891.5066 1.77 11200 13749 2 891.50789 446.7606 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 3010.1 - 5.46E+06 - - - 1.4818 - 1.71 0.224 - 197.5 1 2 0 0.0013 8 0 0 0 3.02E+08 1.71E+08 - - - 2.3131 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.13751.13751.2 0.00578 22-Oct R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 2.33 11202 13751 2 1343.712558 672.8615 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 3010.3 - 232234 - - - 3.0081 - 1.925 0.396 - 193.3 1 2 0 0.004 12 0 0 0 1.37E+07 5.88E+06 - - - 3.6878 0.859 230117_WJC_METTL3_WT_vs_EV_F02.13755.13755.2 0.00338 12-Jul R.FESILPR[166.11].P sp|Q08211|DHX9_HUMAN 1 870.4839 0.88 11204 13755 2 870.485512 436.2492 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3010.8 - 3.94E+06 - - - 1.8829 - 1.664 0.149 - 171.2 1 1 0 0.0016 7 0 0 0 1.28E+08 1.45E+08 - - - 1.7545 0.9966 230117_WJC_METTL3_WT_vs_EV_F02.13757.13757.2 0.179 14-Jul R.FLGC[160.03]VDIK.D "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 950.4895 1.57 11206 13757 2 950.490826 476.252 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 5.83 3010.9 - 1.56E+06 - - - 1.354 - 1.16 0.243 - 134.7 1 2 0 0.0013 8 0 0 0 4.20E+07 2.68E+07 - - - 1.283 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.13761.13761.2 0.014 14-Jul K.AAFAPFGR.L "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 5 835.4341 1.65 11208 13761 2 835.43583 418.7243 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 9.79 3011.4 - 664327 - - - 2.1031 - 1.523 0.263 - 172.7 1 2 0 0.0018 8 0 0 0 2.16E+07 1.31E+07 - - - 2.2517 0.9949 230117_WJC_METTL3_WT_vs_EV_F02.13763.13763.2 0.493 14-May K.VLVPQIPR[166.11].L sp|Q10469|MGAT2_HUMAN 1 930.589 1.08 11210 13763 2 930.590303 466.3018 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 3011.7 - 380699 - - - 1.3927 - 1.148 0.221 - 71.1 2 2 0 0.0013 8 0 0 0 1.06E+08 9.78E+07 - - - 0.9547 0.9833 230117_WJC_METTL3_WT_vs_EV_F02.13768.13768.2 2.8 14-Jul R.FLGC[160.03]VDIK[136.11].D "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 958.5037 1.92 11212 13768 2 958.505214 480.2591 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 5.83 3012.4 - 686884 - - - 1.5389 - 1.117 0.102 - 105.8 1 2 0 0.0015 8 0 0 0 4.09E+07 2.13E+07 - - - 0.1276 0.999 230117_WJC_METTL3_WT_vs_EV_F02.13777.13777.2 0.000487 12-Aug R.FC[160.03]EMLIK.R "sp|Q8WV92|MITD1_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 2 939.4558 0.45 11218 13777 2 939.458259 470.7352 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 5.99 3013.5 - 346200 - - - 2.6217 - 1.412 0.372 - 184.6 1 2 0 0.0025 7 0 0 0 1.69E+07 3.75E+07 - - - 2.881 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.13779.13779.2 0.000639 22-Oct R.TVIIEQSWGSPK[136.11].V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1351.7227 2.33 11220 13779 2 1351.7261 676.8686 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 3013.7 - 219938 - - - 2.5035 - 2.12 0.452 - 285.5 1 2 0 0.0034 12 0 0 0 1.37E+07 5.88E+06 - - - 4.3555 0.9947 230117_WJC_METTL3_WT_vs_EV_F02.13783.13783.2 0.595 12-Jul K.FTAILYR.T "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 882.4963 0.71 11222 13783 2 882.498954 442.2554 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.75 3014.2 - 1.72E+06 - - - 2.9632 - 1.543 0.132 - 208 1 2 0 0.0026 7 0 0 0 1.62E+08 2.28E+08 - - - 1.3894 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.13789.13789.2 0.00508 16-Oct K.VPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1071.5601 1.66 11226 13789 2 1071.563652 536.7873 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 3014.9 - 238111 - - - 3.3512 - 1.614 0.322 - 303.8 1 2 0 0.0036 9 0 0 0 1.75E+07 1.05E+07 - - - 2.8031 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.13790.13790.2 0.00665 16-Aug K.YDGIILPGK.- "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 974.5437 1.3 11227 13790 2 974.546824 488.2791 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.83 3015.1 - 236923 - - - 3.223 - 1.423 0.285 - 193.7 1 2 0 0.0031 9 0 0 0 3.40E+07 2.61E+07 - - - 2.1656 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.13797.13797.2 0.0302 14-Aug K.VLVPQIPR.L sp|Q10469|MGAT2_HUMAN 1 920.5807 1.06 11232 13797 2 920.582912 461.2976 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 3015.9 - 854925 - - - 2.3626 - 1.389 0.405 - 269.6 1 2 0 0.0022 8 0 0 0 1.04E+08 9.76E+07 - - - 3.0226 0.9858 230117_WJC_METTL3_WT_vs_EV_F02.13801.13801.2 1.42 12-Jun R.ISPLQFR.- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 859.4916 3.1 11234 13801 2 859.492162 430.7531 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 3016.4 - 2.69E+06 - - - 0.6678 - 1.258 0.072 - 164.7 1 2 0 0.0006 7 0 0 0 4.39E+08 1.42E+08 - - - 0.2999 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.13802.13802.2 0.909 12-Jul K.LVYILNR[166.11].D sp|Q15393|SF3B3_HUMAN 1 899.5468 1.33 11235 13802 2 899.547632 450.7807 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 3016.4 - 2.64E+06 - - - 0.916 - 1.541 0.178 - 160.2 1 2 0 0.0008 7 0 0 0 3.59E+08 2.71E+08 - - - 1.7256 0.8913 230117_WJC_METTL3_WT_vs_EV_F02.13803.13803.2 0.595 16-Jun K.SSSMTTLAK.N "sp|Q6ZVL6|K154L_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 4 924.4586 10.67 11236 13803 2 924.455047 463.2366 UPF0606 protein KIAA1549L OS=Homo sapiens OX=9606 GN=KIAA1549L PE=2 SV=2 8.47 3016.5 - 644731 - - - -3.879 - 1.352 0.125 - 86.9 2 2 0 -0.0036 9 0 0 0 4.19E+07 3.93E+06 - - - 0.7012 0.9951 230117_WJC_METTL3_WT_vs_EV_F02.13804.13804.2 0.000112 16-Oct K.YDGIILPGK[136.11].- "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 982.5579 1.3 11237 13804 2 982.554663 492.2862 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.83 3016.7 - 379203 - - - -3.2772 - 1.6 0.412 - 308.3 1 2 0 -0.0032 9 0 0 0 3.40E+07 2.61E+07 - - - 3.4428 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.13808.13808.2 0.378 12-Jun K.LVYILNR.D sp|Q15393|SF3B3_HUMAN 1 889.5385 1.32 11239 13808 2 889.540021 445.7765 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 3017.2 - 5.48E+06 - - - 1.6672 - 1.225 0.202 - 152.2 1 2 0 0.0015 7 0 0 0 3.61E+08 2.74E+08 - - - 1.1755 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.13809.13809.2 0.0724 14-Sep K.ITAFIVER[166.11].D "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 957.5523 0.79 11240 13809 2 957.553586 479.7834 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 6 3017.3 - 586729 - - - 1.3566 - 1.859 0.303 - 224.3 1 2 0 0.0013 8 0 0 0 8.58E+07 1.09E+08 - - - 3.1486 0.8631 230117_WJC_METTL3_WT_vs_EV_F02.13810.13810.2 2.51 20-May R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 185 11241 13810 2 1068.6599 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 3017.4 - 549828 - - - 5.244 - 1.248 0.097 - 49.5 5 2 0 0.0056 11 0 0 0 8.49E+07 4.59E+05 - - - 0.0428 0.8661 230117_WJC_METTL3_WT_vs_EV_F02.13811.13811.2 0.0977 14-Aug F.GPVLNYLR[166.11].H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 940.537 0.82 11242 13811 2 940.539517 471.2758 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3017.6 - 480841 - - - 2.707 - 1.624 0.223 - 222.2 1 1 0 0.0025 8 0 0 0 4.51E+07 5.49E+07 - - - 2.1497 0.9896 230117_WJC_METTL3_WT_vs_EV_F02.13813.13813.2 0.182 18-Jun K.ILAEESYLYK[136.11].H sp|Q9NVX0|HAUS2_HUMAN 1 1235.6529 1.56 11244 13813 2 1235.659596 618.8337 HAUS augmin-like complex subunit 2 OS=Homo sapiens OX=9606 GN=HAUS2 PE=1 SV=1 4.53 3017.8 - 157066 - - - 5.415 - 1.379 0.315 - 62.7 1 2 0 0.0067 10 0 0 0 4.36E+06 2.80E+06 - - - 2.2625 0.9899 230117_WJC_METTL3_WT_vs_EV_F02.13815.13815.2 1.94 14-Sep K.TLLAPLSR.G "sp|Q8IWL3|HSC20_HUMAN,tr|B0QYH2|B0QYH2_HUMAN" 2 869.5335 1.76 11245 13815 2 869.535093 435.774 Iron-sulfur cluster co-chaperone protein HscB OS=Homo sapiens OX=9606 GN=HSCB PE=1 SV=3 9.41 3018.1 - 2.79E+06 - - - 1.8872 - 1.214 0.12 - 268.4 1 2 0 0.0016 8 0 0 0 6.14E+07 3.49E+07 - - - 0.5117 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.13816.13816.2 0.209 14-Jul R.NLLSVAYK.N "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB2|A2IDB2_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|K7EIT4|K7EIT4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 22 906.5175 1.52 11246 13816 2 906.520254 454.266 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 8.59 3018.2 - 616397 - - - 3.0733 - 1.514 0.215 - 132.1 1 2 0 0.0028 8 0 0 0 5.21E+08 3.43E+08 - - - 1.879 0.9193 230117_WJC_METTL3_WT_vs_EV_F02.13819.13819.2 0.962 18-Jun K.ILAEESYLYK.H sp|Q9NVX0|HAUS2_HUMAN 1 1227.6387 1.56 11249 13819 2 1227.645864 614.8266 HAUS augmin-like complex subunit 2 OS=Homo sapiens OX=9606 GN=HAUS2 PE=1 SV=1 4.53 3018.5 - 178738 - - - 5.8315 - 1.271 0.137 - 77.2 1 2 0 0.0072 10 0 0 0 4.36E+06 2.80E+06 - - - 0.72 0.9212 230117_WJC_METTL3_WT_vs_EV_F02.13822.13822.2 7.41 12-Jul R.ISPLQFR[166.11].- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 869.4999 3.1 11250 13822 2 869.501781 435.7572 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 3018.9 - 2.86E+06 - - - 2.2116 - 1.099 0.002 - 163.6 2 2 0 0.0019 7 0 0 0 4.38E+08 1.41E+08 - - - -0.7802 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.13824.13824.2 0.0861 14-Jul K.ITAFIVER.D "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 947.544 0.67 11252 13824 2 947.546112 474.7793 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 6 3019.1 - 1.26E+06 - - - 2.211 - 1.408 0.286 - 127.8 1 2 0 0.0021 8 0 0 0 6.92E+07 1.04E+08 - - - 2.1847 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.13825.13825.2 0.00866 14-Aug K.VGVNGFGR.L sp|P04406|G3P_HUMAN 1 804.4242 2.58 11253 13825 2 804.425138 403.2194 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 3019.2 - 1.13E+06 - - - 1.1213 - 1.602 0.357 - 199.7 1 2 0 0.0009 8 0 0 0 4.91E+07 1.90E+07 - - - 3.0988 0.9951 230117_WJC_METTL3_WT_vs_EV_F02.13830.13830.2 2.62 12-Jul R.LVQLLVK.A sp|P14923|PLAK_HUMAN 1 811.5531 17 11256 13830 2 811.554407 406.7838 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 8.75 3019.8 - 1.28E+06 - - - 1.5797 - 1.63 0.056 - 100.9 1 2 0 0.0013 7 0 0 0 2.93E+08 1.72E+07 - - - 1.0023 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.13835.13835.2 0.00865 14-Aug R.VIFTSPIK[136.11].A sp|P42285|MTREX_HUMAN 1 911.5572 1.1 11259 13835 2 911.557467 456.7859 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 8.72 3020.5 - 1.17E+06 - - - 0.3434 - 1.405 0.324 - 202.2 1 2 0 0.0003 8 0 0 0 1.27E+08 1.16E+08 - - - 2.4595 0.9614 230117_WJC_METTL3_WT_vs_EV_F02.13838.13838.4 0.0812 Nov-96 T.LLLIILTDVFIISTVLR.L sp|Q8NGY0|O10X1_HUMAN 1 1941.2278 2777.02 11260 13838 4 1941.235054 486.3142 Olfactory receptor 10X1 OS=Homo sapiens OX=9606 GN=OR10X1 PE=3 SV=2 5.84 3020.9 - 1.81E+06 - - - 3.7255 - 1.625 0.331 - 66.9 1 1 0 0.0072 17 0 0 0 7.57E+07 2.72E+04 - - - 2.2736 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.13847.13847.2 0.134 18-Oct R.YPVNSVNILK.A "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1145.6445 26.45 11263 13847 2 1145.648297 573.8295 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.59 3022.1 - 391334 - - - 3.3501 - 1.736 0.32 - 256.8 1 2 0 0.0038 10 0 0 0 1.80E+07 6.79E+05 - - - 2.943 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.13851.13851.2 0.0202 12-Jul R.YYFEGIK.Q "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN" 3 918.4487 2.36 11264 13851 2 918.449374 460.2316 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 6 3022.7 - 1.30E+06 - - - 0.7121 - 1.232 0.307 - 140.7 1 2 0 0.0007 7 0 0 0 6.05E+07 2.57E+07 - - - 1.9694 0.9797 230117_WJC_METTL3_WT_vs_EV_F02.13861.13861.2 0.322 16-May R.VPPEFLVQR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1093.616 1.51 11271 13861 2 1093.617012 547.8153 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3023.7 - 194446 - - - 0.9711 - 1.059 0.156 - 54.1 6 2 0 0.0011 9 0 0 0 2.55E+07 1.69E+07 - - - 0.0111 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.13865.13865.2 0.0138 12-Jun K.FYIDPYK.L sp|Q9NY12|GAR1_HUMAN 1 944.4644 0.79 11272 13865 2 944.466258 473.2395 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3024.3 - 2.25E+06 - - - 1.999 - 1.183 0.307 - 132 1 2 0 0.0019 7 0 0 0 1.01E+09 1.28E+09 - - - 1.8404 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.13871.13871.2 0.103 12-Jul R.TIPVVFK.D "sp|P25685|DNJB1_HUMAN,tr|A0A7I2V3K7|A0A7I2V3K7_HUMAN" 2 802.4953 0.7 11276 13871 2 802.496789 402.2549 DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4 8.41 3025 - 1.58E+06 - - - 1.8854 - 1.281 0.304 - 167.3 1 2 0 0.0015 7 0 0 0 5.80E+07 8.33E+07 - - - 2.0705 0.987 230117_WJC_METTL3_WT_vs_EV_F02.13878.13878.2 0.308 16-Jun R.VPPEFLVQR.A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1083.6077 1.21 11280 13878 2 1083.609624 542.8111 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3025.8 - 503131 - - - 1.794 - 1.271 0.08 - 95.3 1 2 0 0.0019 9 0 0 0 2.65E+07 2.19E+07 - - - 0.325 0.965 230117_WJC_METTL3_WT_vs_EV_F02.13879.13879.2 0.662 12-May R.FPPYYMR[166.11].R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 982.461 0.8 11281 13879 2 982.459883 492.2378 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 3025.9 - 266531 - - - -1.1665 - 0.93 0.209 - 72.8 1 2 0 -0.0011 7 0 0 0 1.44E+07 1.81E+07 - - - 0.3544 0.9567 230117_WJC_METTL3_WT_vs_EV_F02.13887.13887.2 1.5 14-Jul R.SLASLALR.V sp|Q68D91|MBLC2_HUMAN 1 829.5022 1.58 11283 13887 2 829.502817 415.7584 Acyl-coenzyme A thioesterase MBLAC2 OS=Homo sapiens OX=9606 GN=MBLAC2 PE=1 SV=3 9.47 3027.1 - 545358 - - - 0.8017 - 1.14 0.032 - 118 2 2 0 0.0007 8 0 0 0 2.38E+07 1.51E+07 - - - -0.4622 0.9763 230117_WJC_METTL3_WT_vs_EV_F02.13895.13895.2 2.4 14-Sep R.LATEFELR[166.11].K sp|A5YKK6|CNOT1_HUMAN 1 987.5265 0.9 11287 13895 2 987.526156 494.7705 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.53 3028.1 - 286647 - - - -0.3139 - 1.353 0.042 - 251.1 1 2 0 -0.0003 8 0 0 0 2.01E+07 2.23E+07 - - - 0.2629 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.13896.13896.2 4.29E-06 13/18 R.MVNHFIAEFK.R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1234.6169 3.45 11288 13896 2 1234.619686 618.3157 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 3028.2 - 321225 - - - 2.2849 - 2.135 0.32 - 563 1 2 0 0.0028 10 0 0 0 8.12E+06 2.36E+06 - - - 3.5207 0.9892 230117_WJC_METTL3_WT_vs_EV_F02.13900.13900.2 0.164 14-Jun R.LPWAVAGR.S sp|Q8NBX0|SCPDL_HUMAN 1 868.4919 2.19 11289 13900 2 868.493038 435.2532 Saccharopine dehydrogenase-like oxidoreductase OS=Homo sapiens OX=9606 GN=SCCPDH PE=1 SV=1 9.75 3028.8 - 837211 - - - 1.285 - 1.265 0.09 - 105.3 1 2 0 0.0011 8 0 0 0 7.91E+07 3.61E+07 - - - 0.4144 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.13904.13904.3 0.000178 Nov-36 R.MVNHFIAEFK.R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1234.6169 1.26 11290 13904 3 1234.619656 412.5462 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 3029.4 - 1.32E+06 - - - 2.2606 - 1.773 0.399 - 113.2 1 2 0 0.0028 10 0 0 0 4.37E+07 3.46E+07 - - - 4.6601 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.13906.13906.2 0.00311 12-Aug K.LFEMAYK.K "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 900.4415 4.26 11291 13906 2 900.442225 451.228 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6 3029.6 - 2.99E+06 - - - 0.7763 - 1.421 0.395 - 202.7 1 2 0 0.0007 7 0 0 0 9.90E+08 2.33E+08 - - - 3.0716 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.13908.13908.2 1.68 18-Oct R.VLAESLGPLR.E sp|Q4KMQ1|TPRN_HUMAN 1 1053.6182 1.06 11292 13908 2 1053.617393 527.8164 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 5.97 3029.8 - 325237 - - - -0.8086 - 1.734 0.23 - 257 1 2 0 -0.0009 10 0 0 0 5.45E+07 5.15E+07 - - - 2.2759 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.13917.13917.2 0.0793 12-Jun K.LFEMAYK[136.11].K "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 908.4557 4.21 11297 13917 2 908.457221 455.2351 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6 3031 - 1.99E+06 - - - 1.6456 - 1.384 0.331 - 108.6 1 2 0 0.0015 7 0 0 0 9.90E+08 2.35E+08 - - - 2.515 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.13918.13918.2 0.00404 18-Aug K.VLQSALAAIR.H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1040.6342 1.06 11298 13918 2 1040.634906 521.3244 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 3031.1 - 332406 - - - 0.6506 - 1.626 0.357 - 174.3 1 2 0 0.0007 10 0 0 0 2.75E+08 2.59E+08 - - - 3.0345 0.9722 230117_WJC_METTL3_WT_vs_EV_F02.13925.13925.2 7.45 12-Jul R.LELDALR.S "sp|O60675|MAFK_HUMAN,sp|Q9ULX9|MAFF_HUMAN,sp|O15525|MAFG_HUMAN,tr|B0QY71|B0QY71_HUMAN,tr|B0QY70|B0QY70_HUMAN" 5 828.4705 0.61 11303 13925 2 828.470627 415.2425 Transcription factor MafK OS=Homo sapiens OX=9606 GN=MAFK PE=1 SV=1 4.37 3032 - 454581 - - - 0.1316 - 1.25 0.033 - 130 1 2 0 0.0001 7 0 0 0 1.87E+07 3.07E+07 - - - -0.0083 0.9858 230117_WJC_METTL3_WT_vs_EV_F02.13926.13926.2 0.35 14-Sep K.IAADILIK.E "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 855.543 0.91 11304 13926 2 855.540362 428.7788 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.84 3032.1 - 400809 - - - -3.0297 - 1.647 0.198 - 144.2 1 2 0 -0.0026 8 0 0 0 1.56E+07 1.71E+07 - - - 2.0074 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.13930.13930.2 0.00179 16-Sep R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 999 11306 13930 2 1030.593227 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 3032.6 - 1.88E+07 - - - 2.1347 - 2.003 0.397 - 239.6 1 2 0 0.0022 9 0 0 0 4.62E+09 0.00E+00 - - - 3.9822 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.13931.13931.2 0.0354 18-Oct K.VLQSALAAIR[166.11].H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1050.6425 1.06 11307 13931 2 1050.644217 526.3285 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 3032.7 - 499078 - - - 1.6352 - 2.258 0.278 - 330.5 1 2 0 0.0017 10 0 0 0 2.75E+08 2.59E+08 - - - 3.3672 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.13942.13942.2 0.000115 28-Jul K.NQVALNPQNTVFDAK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1657.8424 999 11316 13942 2 1657.842912 829.9285 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3034 - 99630.9 - - - 0.3185 - 1.626 0.468 - 105.9 1 2 0 0.0005 15 0 0 0 3.42E+06 0.00E+00 - - - 3.6926 0.9969 230117_WJC_METTL3_WT_vs_EV_F02.13945.13945.2 0.000881 14-Jul R.VLVLVPTR.E "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 895.5855 0.91 11317 13945 2 895.586667 448.8 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 9.72 3034.4 - 1.23E+06 - - - 1.3165 - 1.5 0.146 - 163.1 1 2 0 0.0012 8 0 0 0 6.05E+07 6.66E+07 - - - 1.3418 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.13959.13959.2 0.534 16-Aug R.IIFSPVAPK.E sp|O15294|OGT1_HUMAN 1 970.5852 1.26 11326 13959 2 970.585583 486.2999 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 8.75 3036.1 - 1.13E+06 - - - 0.442 - 1.576 0.267 - 153.5 1 2 0 0.0004 9 0 0 0 7.30E+07 5.81E+07 - - - 2.3289 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.13963.13963.2 0.433 18-Oct K.LAEALYIADR[166.11].K "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1143.6163 1.51 11329 13963 2 1143.617122 572.8154 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 3036.6 - 263949 - - - 0.6803 - 1.984 0.125 - 314.9 1 2 0 0.0008 10 0 0 0 4.86E+07 3.23E+07 - - - 1.8764 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.13964.13964.2 2.04 18-Nov K.LAEALYIADR.K "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1133.6081 0.58 11330 13964 2 1133.611533 567.8113 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 3036.8 - 259370 - - - 3.0513 - 2.512 0.298 - 462.8 1 2 0 0.0035 10 0 0 0 6.49E+07 1.11E+08 - - - 3.812 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.13975.13975.2 0.00198 16-Aug K.FTPGAVMLR.V "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 990.5321 1.36 11337 13975 2 990.532697 496.2733 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.75 3038 - 260543 - - - 0.631 - 1.387 0.361 - 150.2 1 2 0 0.0006 9 0 0 0 4.61E+07 3.38E+07 - - - 2.6536 0.9969 230117_WJC_METTL3_WT_vs_EV_F02.13979.13979.2 0.0736 12-Jul R.NLVSYLK.Q "sp|Q96T37|RBM15_HUMAN,sp|Q8NDT2|RB15B_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 5 835.4804 0.74 11339 13979 2 835.481061 418.7475 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 8.59 3038.5 - 742822 - - - 0.8462 - 1.352 0.19 - 168.9 1 2 0 0.0007 7 0 0 0 2.31E+07 3.12E+07 - - - 1.3997 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.13982.13982.2 0.00281 18-Oct R.VLAESLGPLR[166.11].E sp|Q4KMQ1|TPRN_HUMAN 1 1063.6265 1.25 11342 13982 2 1063.627358 532.8205 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 5.97 3038.7 - 1.09E+06 - - - 0.7926 - 1.866 0.305 - 363.7 1 2 0 0.0008 10 0 0 0 5.43E+07 4.35E+07 - - - 3.0347 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.13983.13983.2 0.0672 14-Jul R.YPEEFALR.D "sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN" 4 1023.5025 0.36 11343 13983 2 1023.502617 512.7585 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.53 3038.9 - 349174 - - - 0.0694 - 1.217 0.335 - 140.8 1 2 0 0.0001 8 0 0 0 1.50E+07 4.20E+07 - - - 2.1076 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.13988.13988.2 0.111 12-Jul R.LVWYC[160.03]AR[166.11].C "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 976.4828 1.72 11346 13988 2 976.483122 489.2487 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.22 3039.5 - 540161 - - - 0.3011 - 1.256 0.343 - 144.5 1 2 0 0.0003 7 0 0 0 2.09E+07 1.21E+07 - - - 2.2965 0.9949 230117_WJC_METTL3_WT_vs_EV_F02.13992.13992.2 0.216 14-Aug R.VVIQEMLK[136.11].T sp|P40938|RFC3_HUMAN 1 966.5663 3.45 11347 13992 2 966.566246 484.2904 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 5.97 3040.1 - 437999 - - - -0.0962 - 1.337 0.188 - 107 1 2 0 -0.0001 8 0 0 0 7.39E+07 2.14E+07 - - - 1.3055 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.13993.13993.2 0.0107 14-Jul R.LPLATIVK[136.11].D sp|O94776|MTA2_HUMAN 1 861.5779 1.51 11348 13993 2 861.577705 431.7962 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 3040.2 - 393072 - - - -0.2147 - 1.23 0.363 - 78.8 1 2 0 -0.0002 8 0 0 0 2.55E+08 1.69E+08 - - - 2.3464 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.13995.13995.2 0.0162 12-Jul R.LVWYC[160.03]AR.C "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 966.4746 1.72 11350 13995 2 966.476678 484.2446 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.22 3040.4 - 437999 - - - 2.1935 - 1.236 0.34 - 150.8 1 2 0 0.0021 7 0 0 0 2.08E+07 1.21E+07 - - - 2.2229 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.14001.14001.2 0.0209 12-Jul K.FYIDPYK[136.11].L sp|Q9NY12|GAR1_HUMAN 1 952.4786 0.79 11353 14001 2 952.480378 477.2466 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3041.2 - 1.81E+06 - - - 1.8982 - 1.518 0.348 - 196.8 1 2 0 0.0018 7 0 0 0 1.01E+09 1.28E+09 - - - 2.9333 0.9907 230117_WJC_METTL3_WT_vs_EV_F02.14002.14002.2 0.0882 16-Jul R.VVSEIPVLK.T sp|Q9Y3C8|UFC1_HUMAN 1 982.6063 1.65 11354 14002 2 982.609395 492.3104 Ubiquitin-fold modifier-conjugating enzyme 1 OS=Homo sapiens OX=9606 GN=UFC1 PE=1 SV=3 5.97 3041.4 - 215633 - - - 3.1671 - 1.091 0.237 - 97.5 1 2 0 0.0031 9 0 0 0 1.26E+07 7.63E+06 - - - 1.0425 0.9964 230117_WJC_METTL3_WT_vs_EV_F02.14005.14005.2 0.346 12-Jul R.LFVLTTK.N sp|Q96RS6|NUDC1_HUMAN 1 820.5058 2.67 11355 14005 2 820.506896 411.2602 NudC domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NUDCD1 PE=1 SV=2 8.75 3041.8 - 599553 - - - 1.2858 - 1.537 0.111 - 133.2 1 2 0 0.0011 7 0 0 0 3.28E+07 1.23E+07 - - - 1.2225 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.14017.14017.2 0.00878 14-Sep K.IDNIVLMK[136.11].D "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 952.5507 2.61 11359 14017 2 952.551385 477.2826 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 5.84 3043.3 - 1.22E+06 - - - 0.7307 - 1.902 0.275 - 171.8 1 2 0 0.0007 8 0 0 0 9.91E+07 3.80E+07 - - - 3.0109 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.14023.14023.2 1.65 14-Jun R.AQVSLLIR[166.11].R "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 908.5683 1.22 11362 14023 2 908.569383 455.2914 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 9.79 3044 - 1.17E+06 - - - 1.2228 - 1.296 0.23 - 100.5 1 2 0 0.0011 8 0 0 0 5.18E+07 4.26E+07 - - - 1.5214 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.14031.14031.2 0.00857 16-Jul K.FTPGAVMLR[166.11].V "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1000.5403 2.06 11366 14031 2 1000.541294 501.2774 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.75 3045 - 451520 - - - 0.9515 - 1.321 0.291 - 131.8 1 2 0 0.001 9 0 0 0 4.23E+07 2.05E+07 - - - 1.9954 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.14048.14048.2 0.000278 18-Oct R.VPLVAPEDLR[166.11].D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1117.6371 0.5 11376 14048 2 1117.638657 559.8258 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3047 - 505337 - - - 1.4119 - 2.141 0.41 - 390.4 1 2 0 0.0016 10 0 0 0 8.20E+08 1.63E+09 - - - 4.1937 0.998 230117_WJC_METTL3_WT_vs_EV_F02.14051.14051.2 0.0377 14-Aug R.EAVLSLYR.A sp|L0R8F8|MIDUO_HUMAN 1 949.5233 0.99 11377 14051 2 949.524075 475.7689 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 6.1 3047.4 - 1.73E+06 - - - 0.8352 - 1.372 0.242 - 196.1 1 2 0 0.0008 8 0 0 0 4.68E+07 4.70E+07 - - - 1.782 0.8923 230117_WJC_METTL3_WT_vs_EV_F02.14053.14053.2 3.58 20-May R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 999 11378 14053 2 1068.658679 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 3047.6 - 1.11E+06 - - - 4.1014 - 1.245 0.04 - 57.7 3 2 0 0.0044 11 0 0 0 1.49E+08 0.00E+00 - - - -0.2853 0.9684 230117_WJC_METTL3_WT_vs_EV_F02.14060.14060.2 0.248 14-Aug R.EAVLSLYR[166.11].A sp|L0R8F8|MIDUO_HUMAN 1 959.5316 1.1 11383 14060 2 959.534043 480.7731 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 6.1 3048.4 - 2.22E+06 - - - 2.5961 - 1.334 0.004 - 181.8 1 2 0 0.0025 8 0 0 0 4.68E+07 4.26E+07 - - - -0.0611 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.14067.14067.2 0.00487 14-Jul K.LYLADPMK.A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 949.4943 1.53 11388 14067 2 949.493241 475.7544 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 3049.3 - 1.51E+06 - - - -1.1048 - 1.362 0.405 - 149.4 1 2 0 -0.001 8 0 0 0 2.64E+08 1.73E+08 - - - 2.9638 0.9818 230117_WJC_METTL3_WT_vs_EV_F02.14069.14069.2 0.15 12-Jun R.LYFC[160.03]VDR.G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 971.4535 1.72 11390 14069 2 971.450717 486.734 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 5.83 3049.5 - 341826 - - - -2.8524 - 1.188 0.283 - 88.9 1 2 0 -0.0028 7 0 0 0 7.99E+07 4.66E+07 - - - 1.6762 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.14073.14073.2 7.80E-05 18-Nov R.VPLVAPEDLR.D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1107.6288 0.5 11392 14073 2 1107.631049 554.8217 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3050 - 875329 - - - 2.0223 - 2.267 0.396 - 647 1 2 0 0.0022 10 0 0 0 8.20E+08 1.63E+09 - - - 4.2497 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.14082.14082.2 0.0263 14-Aug K.LYLADPMK[136.11].A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 957.5085 1.53 11395 14082 2 957.508609 479.7615 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 3051.4 - 3.14E+06 - - - 0.1243 - 1.617 0.325 - 177.5 1 2 0 0.0001 8 0 0 0 2.64E+08 1.72E+08 - - - 2.8908 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14094.14094.2 0.000558 18-Aug K.NLQEAEEWYK.S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1308.5986 1.9 11401 14094 2 1308.598762 655.3066 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3052.8 - 244739 - - - 0.0993 - 1.732 0.518 - 172.3 1 2 0 0.0001 10 0 0 0 1.75E+07 9.21E+06 - - - 4.4001 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.14103.14103.2 0.000107 18-Oct K.NLQEAEEWYK[136.11].S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1316.6128 1.92 11406 14103 2 1316.615433 659.3137 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3053.9 - 241441 - - - 1.9755 - 1.799 0.457 - 316.8 1 2 0 0.0026 10 0 0 0 1.77E+07 9.21E+06 - - - 4.0547 0.9888 230117_WJC_METTL3_WT_vs_EV_F02.14107.14107.2 1.76 12-Jul K.VTLGLIR.K sp|Q9NQT5|EXOS3_HUMAN 1 770.5014 1.08 11408 14107 2 770.502416 386.258 Exosome complex component RRP40 OS=Homo sapiens OX=9606 GN=EXOSC3 PE=1 SV=3 9.72 3054.4 - 719287 - - - 1.2875 - 1.497 0.01 - 187 1 2 0 0.001 7 0 0 0 4.87E+07 4.50E+07 - - - 0.3929 0.908 230117_WJC_METTL3_WT_vs_EV_F02.14117.14117.3 0.365 Jun-68 R.VAPEEHPVLLTEAPLNPK.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1953.0571 5.56 11414 14117 3 1953.055895 652.0263 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 3055.6 - 171388 - - - -0.6313 - 1.388 0.153 - 19.2 16 2 0 -0.0012 18 0 0 0 3.91E+06 7.04E+05 - - - 0.5046 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.14123.14123.2 0.0384 14-Aug R.VWAEYALK[136.11].R sp|Q6P2Q9|PRP8_HUMAN 1 986.5317 1.28 11419 14123 2 986.534218 494.2731 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3056.3 - 2.48E+06 - - - 2.5848 - 1.454 0.337 - 261 1 2 0 0.0026 8 0 0 0 1.97E+08 1.55E+08 - - - 2.6582 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.14125.14125.2 0.0125 26-Jun K.IFVGGLSPDTPEEK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1487.7508 1.34 11420 14125 2 1487.754543 744.8827 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3056.5 - 219534 - - - 2.5327 - 1.405 0.351 - 41.7 2 2 0 0.0038 14 0 0 0 7.37E+06 5.52E+06 - - - 2.3511 0.998 230117_WJC_METTL3_WT_vs_EV_F02.14130.14130.2 0.011 16-Sep R.VPPEFLVQR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1093.616 1.53 11423 14130 2 1093.617201 547.8153 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3057.1 - 313084 - - - 1.1439 - 1.372 0.237 - 257.7 1 2 0 0.0013 9 0 0 0 2.15E+07 1.40E+07 - - - 1.7061 0.9951 230117_WJC_METTL3_WT_vs_EV_F02.14134.14134.2 0.138 20-May K.YFVEAGAMAVR[166.11].R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1222.6044 10.38 11425 14134 2 1222.604754 612.3095 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3057.6 - 107412 - - - 0.2904 - 1.183 0.227 - 88.1 1 2 0 0.0004 11 0 0 0 9.28E+08 8.94E+07 - - - 1.1721 1 230117_WJC_METTL3_WT_vs_EV_F02.14136.14136.2 0.000262 20-Dec K.YFVEAGAMAVR.R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1212.5961 10.38 11426 14136 2 1212.596724 607.3053 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3057.8 - 1.49E+06 - - - 0.4907 - 2.396 0.584 - 546.7 1 2 0 0.0006 11 0 0 0 9.29E+08 8.95E+07 - - - 5.7181 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.14146.14146.2 0.0505 12-Aug R.FTDILVR.H sp|O43143|DHX15_HUMAN 1 862.4913 1.13 11432 14146 2 862.492114 432.2529 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 3059 - 1.97E+07 - - - 0.9983 - 1.499 0.309 - 255.9 1 2 0 0.0009 7 0 0 0 4.94E+08 4.39E+08 - - - 2.6056 0.9917 230117_WJC_METTL3_WT_vs_EV_F02.14147.14147.2 2.41 14-Jul K.LLGPVLVK.Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 837.5688 3.78 11433 14147 2 837.569011 419.7917 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 3059.2 - 889678 - - - 0.2818 - 1.483 0.075 - 82.1 1 2 0 0.0002 8 0 0 0 1.04E+09 2.76E+08 - - - 0.7834 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.14148.14148.2 0.0107 12-Jul R.FTDILVR[166.11].H sp|O43143|DHX15_HUMAN 1 872.4995 1.12 11434 14148 2 872.501081 437.257 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 3059.2 - 1.88E+07 - - - 1.7857 - 1.468 0.373 - 170.6 1 2 0 0.0016 7 0 0 0 4.95E+08 4.41E+08 - - - 3.0119 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14155.14155.2 0.109 12-Aug R.VFDMLNR[166.11].R "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 12 903.4512 1.57 11440 14155 2 903.453126 452.7329 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3060 - 1.43E+06 - - - 2.1396 - 1.748 0.422 - 266.7 1 2 0 0.0019 7 0 0 0 6.40E+07 4.07E+07 - - - 3.9268 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.14157.14157.2 0.00408 16-Nov K.LADMGIAIR[166.11].V sp|Q9Y3I0|RTCB_HUMAN 1 968.5353 1.27 11441 14157 2 968.536908 485.2749 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.84 3060.2 - 3.24E+06 - - - 1.7046 - 2.069 0.154 - 394.7 1 2 0 0.0017 9 0 0 0 2.74E+08 2.15E+08 - - - 2.2814 0.9603 230117_WJC_METTL3_WT_vs_EV_F02.14158.14158.2 6.29 14-Jun K.LLGPVLVK[136.11].Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 845.583 3.78 11442 14158 2 845.583163 423.7988 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 3060.3 - 1.21E+06 - - - 0.2223 - 1.058 0.088 - 58.5 2 2 0 0.0002 8 0 0 0 1.04E+09 2.76E+08 - - - -0.2735 0.9529 230117_WJC_METTL3_WT_vs_EV_F02.14159.14159.2 13.3 12-Jun R.LISSLLR[166.11].T "sp|Q9BQ52|RNZ2_HUMAN,sp|Q8NCN5|PDPR_HUMAN,sp|Q96P20|NLRP3_HUMAN,sp|Q96MN2|NALP4_HUMAN,sp|Q8NGV5|O13D1_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|A0A7I2PMC6|A0A7I2PMC6_HUMAN,tr|E7ES68|E7ES68_HUMAN,tr|A0A2R8YEG7|A0A2R8YEG7_HUMAN,tr|A8MT40|A8MT40_HUMAN,tr|A0A7I2PJH0|A0A7I2PJH0_HUMAN,tr|H3BQG3|H3BQG3_HUMAN,tr|A0A7I2PRX0|A0A7I2PRX0_HUMAN,tr|A0A7I2YME5|A0A7I2YME5_HUMAN,tr|A0A286YF94|A0A286YF94_HUMAN,tr|A0A7I2UNQ2|A0A7I2UNQ2_HUMAN,tr|A0A7I2R3P8|A0A7I2R3P8_HUMAN" 17 810.5203 1.63 11443 14159 2 810.520786 406.2674 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 9.75 3060.4 - 1.64E+06 - - - 0.6502 - 1.148 0.062 - 59.8 9 2 0 0.0005 7 0 0 0 4.69E+07 2.87E+07 - - - -0.4902 1 230117_WJC_METTL3_WT_vs_EV_F02.14162.14162.2 2.50E-05 26-Oct K.IFVGGLSPDTPEEK[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1495.765 1.34 11446 14162 2 1495.767813 748.8898 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3060.8 - 332923 - - - 1.8974 - 2.096 0.583 - 295.2 1 2 0 0.0028 14 0 0 0 7.37E+06 5.52E+06 - - - 5.2032 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.14173.14173.2 0.0358 18-Aug R.VPYVIISAAK.G "sp|P28340|DPOD1_HUMAN,tr|M0QXQ2|M0QXQ2_HUMAN,tr|M0QXE6|M0QXE6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 5 1059.6328 0.14 11452 14173 2 1059.633989 530.8237 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.56 3062.1 - 474914 - - - 1.0919 - 1.643 0.287 - 149.5 1 2 0 0.0012 10 0 0 0 9.24E+06 6.72E+07 - - - 2.5464 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.14177.14177.2 0.352 12-Aug R.VFDMLNR.R "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 12 893.4429 1.57 11454 14177 2 893.443714 447.7287 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3062.6 - 2.83E+06 - - - 0.8853 - 1.365 0.316 - 283.7 1 2 0 0.0008 7 0 0 0 6.38E+07 4.07E+07 - - - 2.3606 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14185.14185.2 0.00658 22-Dec K.SPILVATAVAAR[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1177.7058 1.1 11460 14185 2 1177.7067 589.8602 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3063.6 - 321351 - - - 0.7404 - 2.184 0.349 - 253.3 1 2 0 0.0009 12 0 0 0 5.80E+08 5.26E+08 - - - 3.6738 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.14191.14191.2 0.0658 14-Jul K.AINTFFAK[136.11].N "sp|Q71RC2|LARP4_HUMAN,tr|Q96J85|Q96J85_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 3 918.5055 1.59 11464 14191 2 918.507003 460.26 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 8.8 3064.3 - 951263 - - - 1.6875 - 1.33 0.375 - 127.7 1 2 0 0.0015 8 0 0 0 5.15E+07 3.23E+07 - - - 2.6703 0.983 230117_WJC_METTL3_WT_vs_EV_F02.14194.14194.2 0.43 12-Jul R.SLILAMK[136.11].A sp|Q7Z353|HDX_HUMAN 1 782.4815 0.52 11465 14194 2 782.483689 392.248 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 8.47 3064.7 - 1.05E+06 - - - 2.7374 - 1.421 0.035 - 214.2 1 2 0 0.0021 7 0 0 0 1.86E+07 3.55E+07 - - - 0.4121 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.14198.14198.2 0.159 14-Sep R.LPLATIVK.D sp|O94776|MTA2_HUMAN 1 853.5637 1.51 11467 14198 2 853.564733 427.7891 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 3065.2 - 1.49E+06 - - - 1.2219 - 1.429 0.269 - 208 1 2 0 0.001 8 0 0 0 2.53E+08 1.67E+08 - - - 2.1041 1 230117_WJC_METTL3_WT_vs_EV_F02.14203.14203.2 0.000766 22-Dec K.SPILVATAVAAR.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1167.6976 1.1 11468 14203 2 1167.698605 584.8561 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3066 - 1.95E+06 - - - 0.8966 - 2.441 0.486 - 542.6 1 2 0 0.001 12 0 0 0 5.80E+08 5.26E+08 - - - 4.9783 0.9941 230117_WJC_METTL3_WT_vs_EV_F02.14213.14213.2 3.5 14-Aug K.GIGLAIVR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 807.5206 0.93 11473 14213 2 807.520658 404.7676 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 3067.1 - 1.64E+06 - - - 0.0805 - 1.492 0.117 - 205.2 1 2 0 0.0001 8 0 0 0 4.13E+08 4.43E+08 - - - 1.1119 0.9593 230117_WJC_METTL3_WT_vs_EV_F02.14218.14218.2 1.56 12-Jun R.LILPYER.F "sp|Q14865|ARI5B_HUMAN,tr|A0A7P0TAD2|A0A7P0TAD2_HUMAN" 2 902.5226 1.51 11476 14218 2 902.522072 452.2686 AT-rich interactive domain-containing protein 5B OS=Homo sapiens OX=9606 GN=ARID5B PE=1 SV=3 6 3067.8 - 811797 - - - -0.533 - 1.193 0.052 - 117.3 1 2 0 -0.0005 7 0 0 0 1.89E+07 1.25E+07 - - - -0.0159 0.981 230117_WJC_METTL3_WT_vs_EV_F02.14220.14220.2 0.931 14-Jun K.YGIPLAYK[136.11].K "sp|Q96PY6|NEK1_HUMAN,tr|H0Y8M6|H0Y8M6_HUMAN" 2 931.5259 0.08 11478 14220 2 931.525289 466.7702 Serine\threonine-protein kinase Nek1 OS=Homo sapiens OX=9606 GN=NEK1 PE=1 SV=2 8.5 3068 - 229762 - - - -0.6065 - 1.03 0.191 - 61.6 1 2 0 -0.0006 8 0 0 0 8.35E+06 1.11E+08 - - - 0.5407 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.14226.14226.2 0.0111 16-Sep K.VLPLEEAYR.F sp|Q9H223|EHD4_HUMAN 1 1088.5866 1.9 11482 14226 2 1088.588143 545.3006 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 3068.7 - 614991 - - - 1.4082 - 1.529 0.341 - 332.8 1 2 0 0.0015 9 0 0 0 1.79E+08 9.41E+07 - - - 2.7876 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.14233.14233.2 0.00512 14-Aug R.MLQAMGWK.E sp|P98175|RBM10_HUMAN 1 963.467 0.66 11487 14233 2 963.46828 482.7408 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 8.5 3069.6 - 534970 - - - 1.2984 - 1.489 0.336 - 136.4 1 2 0 0.0013 8 0 0 0 8.56E+06 1.30E+07 - - - 2.723 0.9854 230117_WJC_METTL3_WT_vs_EV_F02.14242.14242.2 0.154 14-Sep R.MLQAMGWK[136.11].E sp|P98175|RBM10_HUMAN 1 971.4812 0.66 11492 14242 2 971.47784 486.7479 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 8.5 3070.7 - 609100 - - - -3.4885 - 1.444 0.286 - 189.3 1 2 0 -0.0034 8 0 0 0 8.56E+06 1.30E+07 - - - 2.2604 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.14247.14247.2 0.0442 14-Aug R.LLAMLEQK.N "sp|Q96EA4|SPDLY_HUMAN,tr|H0YBG5|H0YBG5_HUMAN" 2 944.5365 9.38 11495 14247 2 944.536866 473.2755 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 6 3071.3 - 1.17E+06 - - - 0.3991 - 1.508 0.387 - 142.5 1 2 0 0.0004 8 0 0 0 3.09E+07 3.29E+06 - - - 3.1382 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.14255.14255.2 0.197 16-Sep K.VLPLEEAYR[166.11].F sp|Q9H223|EHD4_HUMAN 1 1098.5949 2.47 11501 14255 2 1098.595732 550.3047 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 3072.3 - 1.27E+06 - - - 0.7755 - 1.349 0.264 - 272.1 1 2 0 0.0009 9 0 0 0 1.33E+08 5.41E+07 - - - 1.8567 0.9945 230117_WJC_METTL3_WT_vs_EV_F02.14265.14265.2 0.205 12-Jul K.YPLLISR.L "sp|Q92974|ARHG2_HUMAN,tr|A0A5F9ZI21|A0A5F9ZI21_HUMAN,tr|V9GYM8|V9GYM8_HUMAN" 3 860.512 1.03 11507 14265 2 860.512314 431.2633 Rho guanine nucleotide exchange factor 2 OS=Homo sapiens OX=9606 GN=ARHGEF2 PE=1 SV=4 8.75 3073.5 - 1.03E+06 - - - 0.3777 - 1.429 0.12 - 165.4 1 2 0 0.0003 7 0 0 0 5.51E+07 5.37E+07 - - - 1.0583 0.9922 230117_WJC_METTL3_WT_vs_EV_F02.14267.14267.2 0.0724 16-Jul R.VLGVLEVSR.S "sp|Q9H0C8|ILKAP_HUMAN,tr|F8SNU7|F8SNU7_HUMAN,tr|H7C2I8|H7C2I8_HUMAN" 3 970.5811 3.54 11509 14267 2 970.579389 486.2978 Integrin-linked kinase-associated serine\threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1 5.97 3073.8 - 681410 - - - -1.7948 - 1.474 0.227 - 85.3 1 2 0 -0.0017 9 0 0 0 4.07E+07 1.15E+07 - - - 1.8395 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.14275.14275.2 0.00211 14-Jul K.VITMFVQR.Q "sp|P13010|XRCC5_HUMAN,tr|C9JZ81|C9JZ81_HUMAN,tr|H7C0H9|H7C0H9_HUMAN" 3 992.5477 0.76 11515 14275 2 992.552026 497.2811 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 9.72 3074.6 - 336649 - - - 4.3363 - 1.56 0.37 - 133.7 1 2 0 0.0043 8 0 0 0 1.04E+08 1.37E+08 - - - 3.1136 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.14284.14284.2 0.19 18-Aug K.LPAVVTADLR.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1053.6182 2.1 11520 14284 2 1053.619668 527.8164 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.84 3075.8 - 296406 - - - 1.3506 - 1.843 0.299 - 153.7 1 2 0 0.0014 10 0 0 0 4.57E+07 2.18E+07 - - - 2.9556 0.9769 230117_WJC_METTL3_WT_vs_EV_F02.14296.14296.2 15.1 12-Aug K.LLDLLVK.F "sp|O15050|TRNK1_HUMAN,sp|Q6P2Q9|PRP8_HUMAN,tr|A0A2R8YEM9|A0A2R8YEM9_HUMAN,tr|A0A2R8Y8A3|A0A2R8Y8A3_HUMAN" 4 812.5371 2.65 11526 14296 2 812.538274 407.2758 TPR and ankyrin repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=TRANK1 PE=2 SV=4 5.84 3077.3 - 531794 - - - 1.3944 - 1.243 0.042 - 131.9 2 2 0 0.0011 7 0 0 0 4.56E+07 1.72E+07 - - - -0.0944 0.9943 230117_WJC_METTL3_WT_vs_EV_F02.14299.14299.2 0.0324 18-Jul R.VPLVAPEDLR[166.11].D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1117.6371 0.5 11528 14299 2 1117.635364 559.8258 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3077.6 - 104755 - - - -1.5345 - 1.535 0.237 - 135.1 1 2 0 -0.0017 10 0 0 0 8.20E+08 1.63E+09 - - - 1.9871 0.9933 230117_WJC_METTL3_WT_vs_EV_F02.14304.14304.2 0.356 14-May K.VLLSALER[166.11].L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 909.5523 2.56 11531 14304 2 909.554153 455.7834 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.97 3078.1 - 512202 - - - 2.0516 - 1.131 0.195 - 76.4 1 2 0 0.0019 8 0 0 0 5.46E+08 2.14E+08 - - - 0.852 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.14305.14305.2 0.243 12-Jul K.LWNGLVK[136.11].V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 836.5 1.03 11532 14305 2 836.501512 419.2573 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 3078.2 - 562638 - - - 1.8386 - 1.366 0.25 - 101.2 1 2 0 0.0015 7 0 0 0 6.15E+07 5.96E+07 - - - 1.8752 0.9157 230117_WJC_METTL3_WT_vs_EV_F02.14313.14313.2 0.232 12-Sep S.VGAEIQR.L tr|D6RFZ9|D6RFZ9_HUMAN 1 771.4239 0.98 11536 14313 2 771.424787 386.7192 Receptor of-activated protein C kinase 1 (Fragment) OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=8 5.97 3079.2 - 742970 - - - 1.1472 - 1.726 0.199 - 229.6 1 1 0 0.0009 7 0 0 0 1.70E+07 1.73E+07 - - - 2.24 0.9928 230117_WJC_METTL3_WT_vs_EV_F02.14314.14314.2 0.596 16-Sep R.LAEYYGLYR[166.11].D sp|Q96DV4|RM38_HUMAN 1 1156.5792 1.18 11537 14314 2 1156.582396 579.2969 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3079.4 - 569210 - - - 2.7374 - 1.741 0.054 - 271.8 1 2 0 0.0032 9 0 0 0 4.24E+07 3.60E+07 - - - 1.0429 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14316.14316.2 0.0321 16-Sep R.LAEYYGLYR.D sp|Q96DV4|RM38_HUMAN 1 1146.571 1.17 11539 14316 2 1146.572453 574.2928 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3079.6 - 406857 - - - 1.3021 - 2.094 0.316 - 299.8 1 2 0 0.0015 9 0 0 0 4.24E+07 3.62E+07 - - - 3.5127 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14326.14326.2 0.112 16-Oct K.LNSLAIGLR.Q sp|P54886|P5CS_HUMAN 1 955.5815 1.52 11545 14326 2 955.583469 478.798 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3080.9 - 485831 - - - 2.0972 - 2.25 0.331 - 267.8 1 2 0 0.002 9 0 0 0 6.67E+07 4.38E+07 - - - 3.8312 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.14328.14328.2 0.00816 16-Jul K.LLVLDPAQR.L sp|P50750|CDK9_HUMAN 1 1023.6077 1.85 11547 14328 2 1023.609404 512.8111 Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3 5.84 3081 - 565819 - - - 1.6842 - 1.778 0.344 - 147.9 1 2 0 0.0017 9 0 0 0 3.92E+07 2.12E+07 - - - 3.2462 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.14335.14335.2 0.151 14-Jul K.VLETFLAK.S "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 919.5379 1.6 11552 14335 2 919.539352 460.7762 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 5.97 3081.7 - 1.32E+06 - - - 1.6128 - 1.394 0.352 - 140.1 1 2 0 0.0015 8 0 0 0 7.07E+07 4.42E+07 - - - 2.6422 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14343.14343.2 0.0101 16-Sep K.LNSLAIGLR[166.11].Q sp|P54886|P5CS_HUMAN 1 965.5897 1.53 11558 14343 2 965.592094 483.8021 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3082.8 - 895707 - - - 2.4431 - 2.185 0.383 - 249.5 1 2 0 0.0024 9 0 0 0 6.71E+07 4.39E+07 - - - 4.1304 0.9821 230117_WJC_METTL3_WT_vs_EV_F02.14344.14344.2 1.24 14-Jul R.LMTEILGR[166.11].Q "sp|O43809|CPSF5_HUMAN,tr|H3BV41|H3BV41_HUMAN,tr|H3BND3|H3BND3_HUMAN" 3 941.5244 1.32 11559 14344 2 941.525708 471.7695 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3082.9 - 913992 - - - 1.4338 - 1.393 0.005 - 141.7 1 2 0 0.0014 8 0 0 0 6.20E+07 4.69E+07 - - - 0.0772 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.14349.14349.2 0.000841 14-Aug K.VITMFVQR[166.11].Q "sp|P13010|XRCC5_HUMAN,tr|C9JZ81|C9JZ81_HUMAN,tr|H7C0H9|H7C0H9_HUMAN" 3 1002.556 0.76 11562 14349 2 1002.559035 502.2853 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 9.72 3083.5 - 4.56E+06 - - - 3.0352 - 1.796 0.353 - 156.3 1 2 0 0.003 8 0 0 0 1.04E+08 1.36E+08 - - - 3.4133 0.9931 230117_WJC_METTL3_WT_vs_EV_F02.14354.14354.2 1.98 12-Jun R.FPLVSVR.N "sp|Q8NFF5|FAD1_HUMAN,tr|Q5T196|Q5T196_HUMAN" 2 816.4858 4.29 11565 14354 2 816.488421 409.2502 FAD synthase OS=Homo sapiens OX=9606 GN=FLAD1 PE=1 SV=1 9.75 3084.1 - 616961 - - - 3.2419 - 1.318 0.188 - 94.1 1 2 0 0.0026 7 0 0 0 5.41E+07 1.26E+07 - - - 1.3036 0.9467 230117_WJC_METTL3_WT_vs_EV_F02.14358.14358.2 1.46 12-Jun K.EIMLGLK.R "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 802.4623 1.57 11567 14358 2 802.461221 402.2384 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.1 3084.6 - 1.20E+06 - - - -1.296 - 1.146 0.087 - 127.9 1 2 0 -0.001 7 0 0 0 1.21E+08 7.68E+07 - - - 0.1151 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.14361.14361.2 0.00112 20-Sep K.DAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1160.5561 63.5 11569 14361 2 1160.557742 581.2853 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.92 3085 - 348298 - - - 1.4166 - 2.239 0.398 - 246.6 1 2 0 0.0016 11 0 0 0 1.11E+07 1.75E+05 - - - 4.1606 0.9926 230117_WJC_METTL3_WT_vs_EV_F02.14362.14362.2 0.262 12-Jul R.LWEAGWK[136.11].Q sp|Q9H0D6|XRN2_HUMAN 1 896.4636 0.95 11570 14362 2 896.466809 449.2391 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 6 3085 - 1.13E+07 - - - 3.593 - 1.409 0.178 - 205.3 1 2 0 0.0032 7 0 0 0 2.79E+08 2.94E+08 - - - 1.4411 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.14372.14372.2 0.00211 16-Aug R.ILALDC[160.03]GLK.Y "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1001.558 2.06 11575 14372 2 1001.55795 501.7863 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.83 3086.2 - 1.12E+06 - - - -0.003 - 1.947 0.322 - 117.2 1 2 0 0 9 0 0 0 1.28E+08 6.19E+07 - - - 3.3469 0.9954 230117_WJC_METTL3_WT_vs_EV_F02.14381.14381.2 0.00621 28-Sep R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 0.21 11580 14381 2 1410.78923 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3087.4 - 171092 - - - 4.3607 - 1.732 0.268 - 127.5 1 2 0 0.0062 15 0 0 0 8.73E+06 4.20E+07 - - - 2.3689 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.14386.14386.2 0.146 12-Aug K.LSAFAFK.Q sp|O75717|WDHD1_HUMAN 1 782.4327 1.63 11582 14386 2 782.433622 392.2236 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 8.75 3088 - 663500 - - - 1.209 - 1.453 0.224 - 152.5 1 2 0 0.0009 7 0 0 0 2.45E+07 1.50E+07 - - - 1.879 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.14387.14387.2 0.395 12-Jul K.LSAFAFK[136.11].Q sp|O75717|WDHD1_HUMAN 1 790.4469 1.64 11583 14387 2 790.448978 396.2307 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 8.75 3088.1 - 569367 - - - 2.6593 - 1.479 0.163 - 98.8 1 2 0 0.0021 7 0 0 0 2.55E+07 1.55E+07 - - - 1.4843 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.14394.14394.2 0.000332 18-Sep K.LFPGSPAIYK.L "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|F8W705|F8W705_HUMAN,tr|C9JF75|C9JF75_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|C9J6W1|C9J6W1_HUMAN,tr|H0YBN8|H0YBN8_HUMAN,tr|C9J1W9|C9J1W9_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 17 1091.6015 1.9 11586 14394 2 1091.604274 546.808 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 8.59 3089 - 378216 - - - 2.5119 - 1.5 0.422 - 222 1 2 0 0.0027 10 0 0 0 2.47E+07 1.30E+07 - - - 3.2888 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.14399.14399.2 0.0332 12-Jul R.FLDPEFR.E sp|Q5VUA4|ZN318_HUMAN 1 922.4549 1.54 11589 14399 2 922.456823 462.2347 Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2 4.37 3089.6 - 1.16E+06 - - - 2.1193 - 1.358 0.295 - 175.1 1 2 0 0.002 7 0 0 0 4.19E+07 2.72E+07 - - - 2.1889 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.14401.14401.2 0.0232 16-Oct R.ILALDC[160.03]GLK[136.11].Y "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1009.5722 2.12 11590 14401 2 1009.575514 505.7934 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.83 3089.8 - 2.02E+06 - - - 3.3291 - 1.989 0.269 - 255.6 1 2 0 0.0034 9 0 0 0 1.32E+08 6.25E+07 - - - 3.0161 0.998 230117_WJC_METTL3_WT_vs_EV_F02.14404.14404.2 0.157 18-Aug K.IMLVEPPVAK[136.11].V sp|P18583|SON_HUMAN 1 1103.6504 1.51 11593 14404 2 1103.653231 552.8325 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3090.2 - 224094 - - - 2.5624 - 1.662 0.215 - 116 1 2 0 0.0028 10 0 0 0 1.19E+07 7.88E+06 - - - 2.0461 0.9753 230117_WJC_METTL3_WT_vs_EV_F02.14417.14417.2 3.15 12-Jun R.VLGLLER.S "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 798.4963 1.45 11600 14417 2 798.497623 400.2554 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 5.97 3091.9 - 1.98E+06 - - - 1.608 - 1.307 0.016 - 107.8 2 2 0 0.0013 7 0 0 0 4.57E+07 3.15E+07 - - - -0.1274 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.14418.14418.2 0.018 16-Jul R.AYALAFAER[166.11].G "sp|P51659|DHB4_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HLJ0|A0A804HLJ0_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HKT2|A0A804HKT2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN,tr|A0A2R8YEG2|A0A2R8YEG2_HUMAN" 12 1020.5268 2.06 11601 14418 2 1020.526143 511.2707 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6.05 3092 - 376040 - - - -0.6448 - 1.687 0.394 - 176.9 1 2 0 -0.0007 9 0 0 0 2.19E+07 1.06E+07 - - - 3.4638 0.9904 230117_WJC_METTL3_WT_vs_EV_F02.14420.14420.2 0.264 16-Jul K.EVLVLTSVR.N sp|Q13371|PHLP_HUMAN 1 1014.6073 0.31 11603 14420 2 1014.609417 508.3109 Phosducin-like protein OS=Homo sapiens OX=9606 GN=PDCL PE=1 SV=3 6.1 3092.3 - 283757 - - - 2.0412 - 1.413 0.092 - 111 2 2 0 0.0021 9 0 0 0 4.60E+06 1.47E+07 - - - 0.5856 1 230117_WJC_METTL3_WT_vs_EV_F02.14426.14426.2 0.000206 18-Oct R.IATANMLGIR.K sp|Q9NX20|RM16_HUMAN 1 1058.5907 1.15 11607 14426 2 1058.592738 530.3026 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3093.1 - 283665 - - - 1.9724 - 2.344 0.47 - 279.7 1 2 0 0.0021 10 0 0 0 3.93E+07 3.40E+07 - - - 4.8896 0.9753 230117_WJC_METTL3_WT_vs_EV_F02.14428.14428.2 2.32 14-Jun K.GGSLSSIR.R tr|A0A669KBC5|A0A669KBC5_HUMAN 1 775.4188 0.26 11609 14428 2 775.420956 388.7167 Protein unc-80 homolog OS=Homo sapiens OX=9606 GN=UNC80 PE=1 SV=1 9.75 3093.3 - 203255 - - - 2.7585 - 1.226 0.098 - 100.9 3 2 0 0.0021 8 0 0 0 5.44E+06 2.07E+07 - - - 0.1655 0.8619 230117_WJC_METTL3_WT_vs_EV_F02.14433.14433.2 43.8 12-May K.RIYGGFK[136.11].S sp|Q14520|HABP2_HUMAN 1 847.4796 - 11612 14433 2 847.481422 424.7471 Hyaluronan-binding protein 2 OS=Homo sapiens OX=9606 GN=HABP2 PE=1 SV=1 9.99 3093.9 - 1.28E+06 - - - 2.1818 - 0.827 0.095 - 45.5 5 2 0 0.0018 7 0 0 0 - - - - - -1.172 0.9582 230117_WJC_METTL3_WT_vs_EV_F02.14435.14435.2 1.37 16-Oct R.AGVIFPVGR[166.11].L "sp|Q9P0M6|H2AW_HUMAN,sp|O75367|H2AY_HUMAN,tr|A0A7I2YQD6|A0A7I2YQD6_HUMAN,tr|B4DJC3|B4DJC3_HUMAN,tr|A0A7I2V412|A0A7I2V412_HUMAN,tr|Q5SQT3|Q5SQT3_HUMAN,tr|A0A7I2V423|A0A7I2V423_HUMAN,tr|A0A7I2V2N7|A0A7I2V2N7_HUMAN,tr|A0A7I2V4D9|A0A7I2V4D9_HUMAN,tr|D6RCF2|D6RCF2_HUMAN,tr|A0A7I2V6E9|A0A7I2V6E9_HUMAN,tr|A0A7I2YQB9|A0A7I2YQB9_HUMAN,tr|A0A7I2YQR8|A0A7I2YQR8_HUMAN" 13 924.5421 1.5 11614 14435 2 924.545629 463.2783 Core histone macro-H2A.2 OS=Homo sapiens OX=9606 GN=MACROH2A2 PE=1 SV=3 9.79 3094.1 - 613615 - - - 3.8635 - 1.381 0.04 - 310.4 1 2 0 0.0036 9 0 0 0 8.09E+07 5.41E+07 - - - 0.2692 0.9019 230117_WJC_METTL3_WT_vs_EV_F02.14436.14436.2 0.0107 14-Aug N.YIAPEILR.G "sp|P41743|KPCI_HUMAN,sp|Q05513|KPCZ_HUMAN,tr|E9PBE1|E9PBE1_HUMAN" 3 973.5597 0.36 11615 14436 2 973.562713 487.7871 Protein kinase C iota type OS=Homo sapiens OX=9606 GN=PRKCI PE=1 SV=2 6 3094.2 - 484811 - - - 3.1287 - 1.436 0.362 - 231.5 1 1 0 0.003 8 0 0 0 1.36E+07 3.78E+07 - - - 2.8051 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.14440.14440.2 0.0482 18-Oct R.IATANMLGIR[166.11].K sp|Q9NX20|RM16_HUMAN 1 1068.5989 1.17 11617 14440 2 1068.601311 535.3067 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3094.8 - 800710 - - - 2.2375 - 1.786 0.303 - 292.2 1 2 0 0.0024 10 0 0 0 3.83E+07 3.26E+07 - - - 2.8971 0.9914 230117_WJC_METTL3_WT_vs_EV_F02.14442.14442.2 0.0902 12-Jun R.FLTFAER[166.11].L sp|O75691|UTP20_HUMAN 1 892.4682 0.9 11619 14442 2 892.471518 447.2414 Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3 6 3095 - 825954 - - - 3.692 - 1.317 0.215 - 95 2 2 0 0.0033 7 0 0 0 1.07E+07 1.18E+07 - - - 1.366 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.14450.14450.2 0.0347 16-Sep K.TLAIELAPR[166.11].N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 992.5894 1.28 11624 14450 2 992.592724 497.302 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3096.1 - 972175 - - - 3.3478 - 1.745 0.407 - 296.8 1 2 0 0.0033 9 0 0 0 1.91E+09 1.48E+09 - - - 3.6568 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.14455.14455.3 2.86E-05 14/48 R.LVHPGVAEVVFVK[136.11].K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1400.8271 1.37 11629 14455 3 1400.830667 467.9497 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 3096.6 - 732733 - - - 2.5306 - 2.572 0.485 - 270.7 1 2 0 0.0035 13 0 0 0 1.84E+07 1.34E+07 - - - 6.5076 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.14462.14462.2 0.0374 14-Aug K.VPGIFISR.M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 887.5229 0.17 11634 14462 2 887.525543 444.7687 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3097.4 - 1.56E+06 - - - 2.9915 - 1.502 0.311 - 224.4 2 2 0 0.0027 8 0 0 0 7.40E+07 4.44E+08 - - - 2.4296 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.14463.14463.2 0.0996 16-Sep K.TLAIELAPR.N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 982.5811 1.04 11635 14463 2 982.583771 492.2978 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3097.4 - 1.25E+06 - - - 2.6868 - 1.818 0.269 - 292.6 1 2 0 0.0026 9 0 0 0 1.55E+09 1.49E+09 - - - 2.7563 0.9489 230117_WJC_METTL3_WT_vs_EV_F02.14465.14465.2 0.00818 14-Sep M.PTPVILLK.E "sp|Q99832|TCPH_HUMAN,tr|A0A0D9SG95|A0A0D9SG95_HUMAN,tr|F8WBP8|F8WBP8_HUMAN" 3 879.5793 13.87 11637 14465 2 879.581094 440.7969 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 9.18 3097.7 - 683703 - - - 1.9941 - 1.701 0.313 - 269.9 1 1 0 0.0018 8 0 0 0 1.17E+08 8.46E+06 - - - 2.9544 0.9942 230117_WJC_METTL3_WT_vs_EV_F02.14466.14466.2 0.905 14-Aug K.ATALPLLK.Q sp|Q9Y2P8|RCL1_HUMAN 1 825.5324 0.75 11638 14466 2 825.534877 413.7735 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 8.8 3097.8 - 451273 - - - 3.0126 - 1.56 0.129 - 174.7 1 2 0 0.0025 8 0 0 0 3.23E+07 4.29E+07 - - - 1.3342 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.14467.14467.2 0.0166 20-Jul K.LIPGPLSPVAR[166.11].G sp|P48634|PRC2A_HUMAN 1 1128.6894 1.27 11639 14467 2 1128.691785 565.352 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3097.9 - 378258 - - - 2.0697 - 1.529 0.352 - 158.2 1 2 0 0.0023 11 0 0 0 4.79E+08 3.78E+08 - - - 2.7888 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.14472.14472.2 1.32 14-Aug R.IGFIEEVK.A sp|Q96P63|SPB12_HUMAN 1 933.5171 58.08 11642 14472 2 933.518963 467.7658 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 4.53 3098.6 - 1.07E+06 - - - 1.9593 - 1.625 0.155 - 131 1 2 0 0.0018 8 0 0 0 1.47E+08 2.54E+06 - - - 1.6495 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.14474.14474.2 15 12-Oct K.IGIEIIK.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 784.5058 1.2 11644 14474 2 784.506727 393.2602 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3098.8 - 701638 - - - 1.1294 - 1.822 0.025 - 244.4 1 2 0 0.0009 7 0 0 0 6.16E+06 5.13E+06 - - - 1.1263 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.14479.14479.2 0.0284 18-Nov K.LPAVVTADLR[166.11].L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1063.6265 2.43 11647 14479 2 1063.628129 532.8205 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.84 3099.4 - 1.11E+06 - - - 1.5174 - 2.054 0.314 - 494.3 1 2 0 0.0016 10 0 0 0 8.48E+07 3.48E+07 - - - 3.3688 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14481.14481.2 0.00177 18-Sep K.IMLVEPPVAK.V sp|P18583|SON_HUMAN 1 1095.6362 1.8 11649 14481 2 1095.637841 548.8254 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3099.6 - 492528 - - - 1.495 - 1.947 0.364 - 230.2 1 2 0 0.0016 10 0 0 0 3.80E+07 2.12E+07 - - - 3.5888 0.9938 230117_WJC_METTL3_WT_vs_EV_F02.14483.14483.2 0.613 20-Jul M.VPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1175.7278 3.6 11651 14483 2 1175.72914 588.8712 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.72 3099.9 - 282566 - - - 1.144 - 1.397 0.119 - 89 1 2 0 0.0013 11 0 0 0 1.38E+07 3.82E+06 - - - 0.8239 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.14490.14490.2 0.0547 12-Sep R.VVEFLVK.H sp|P42773|CDN2C_HUMAN 1 832.5058 1.2 11657 14490 2 832.506942 417.2602 Cyclin-dependent kinase 4 inhibitor C OS=Homo sapiens OX=9606 GN=CDKN2C PE=1 SV=1 5.97 3100.7 - 1.62E+06 - - - 1.3225 - 1.425 0.253 - 220.9 1 2 0 0.0011 7 0 0 0 2.19E+07 1.82E+07 - - - 2.0315 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.14491.14491.2 0.089 16-Sep R.VLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 969.5859 1.43 11658 14491 2 969.587966 485.8002 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3100.8 - 1.17E+06 - - - 2.1494 - 1.927 0.251 - 216 1 2 0 0.0021 9 0 0 0 9.59E+08 6.72E+08 - - - 2.792 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.14492.14492.2 0.149 16-Jun R.VLQALEGLK[136.11].M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 977.6001 1.43 11659 14492 2 977.604066 489.8073 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3100.8 - 1.04E+06 - - - 4.0753 - 1.476 0.321 - 87.8 1 2 0 0.004 9 0 0 0 9.58E+08 6.72E+08 - - - 2.537 0.9885 230117_WJC_METTL3_WT_vs_EV_F02.14496.14496.2 0.151 18-Jun K.WTLLQEQGTK.T "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1202.6295 8.15 11663 14496 2 1202.633554 602.322 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6 3101.3 - 149614 - - - 3.3393 - 1.435 0.123 - 71 1 2 0 0.004 10 0 0 0 1.45E+06 1.77E+05 - - - 0.9563 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14502.14502.2 8.40E-05 20-Aug K.LIPGPLSPVAR.G sp|P48634|PRC2A_HUMAN 1 1118.6812 1.27 11667 14502 2 1118.682494 560.3479 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3102.1 - 2.61E+06 - - - 1.1755 - 1.603 0.472 - 296.6 1 2 0 0.0013 11 0 0 0 4.80E+08 3.78E+08 - - - 3.8033 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.14503.14503.2 0.133 12-Sep R.IAAYLFK.G "sp|Q00610|CLH1_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|J3KRF5|J3KRF5_HUMAN" 5 824.4796 1.07 11668 14503 2 824.480693 413.2471 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.59 3102.1 - 1.36E+06 - - - 1.2941 - 1.736 0.258 - 231.4 1 2 0 0.0011 7 0 0 0 3.26E+08 3.03E+08 - - - 2.694 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.14504.14504.2 0.00604 14-Sep K.VPGIFISR[166.11].M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 897.5312 1.57 11669 14504 2 897.53185 449.7729 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3102.2 - 1.10E+06 - - - 0.771 - 1.633 0.361 - 252.3 1 2 0 0.0007 8 0 0 0 4.99E+07 3.18E+07 - - - 3.1862 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.14505.14505.2 0.00286 16-Oct R.FLAEEGFYK[136.11].F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1110.5477 1.25 11670 14505 2 1110.548523 556.2811 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3102.4 - 587439 - - - 0.7303 - 1.982 0.406 - 259.9 1 2 0 0.0008 9 0 0 0 1.22E+08 9.72E+07 - - - 4.0186 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14506.14506.2 6.31E-05 16-Aug R.FLAEEGFYK.F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1102.5335 1.25 11671 14506 2 1102.535855 552.274 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3102.5 - 476083 - - - 2.1251 - 1.54 0.498 - 154.5 1 2 0 0.0023 9 0 0 0 1.22E+08 9.72E+07 - - - 3.9677 0.9797 230117_WJC_METTL3_WT_vs_EV_F02.14511.14511.2 0.162 20-Jun K.ILATTPSAVFR.V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1174.671 1.93 11674 14511 2 1174.671941 588.3428 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3103.2 - 204884 - - - 0.7934 - 1.271 0.089 - 80.3 5 2 0 0.0009 11 0 0 0 5.76E+07 2.99E+07 - - - 0.0346 0.9949 230117_WJC_METTL3_WT_vs_EV_F02.14514.14514.2 0.125 14-Jul R.ELVITIAR[166.11].E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 923.5679 1.23 11675 14514 2 923.568357 462.7912 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3103.6 - 3.54E+06 - - - 0.4548 - 1.349 0.156 - 215 1 2 0 0.0004 8 0 0 0 4.14E+08 3.35E+08 - - - 1.096 0.9928 230117_WJC_METTL3_WT_vs_EV_F02.14537.14537.2 0.105 14-Sep K.QFFVAVER[166.11].E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1004.5319 1.09 11690 14537 2 1004.530824 503.2732 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 6 3106.3 - 1.42E+06 - - - -1.0572 - 1.44 0.184 - 226.4 1 2 0 -0.0011 8 0 0 0 7.44E+07 6.85E+07 - - - 1.4994 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.14542.14542.2 0.000478 18-Dec K.AIITALGVER.R sp|Q92616|GCN1_HUMAN 1 1041.6182 1.54 11693 14542 2 1041.618163 521.8164 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 6.05 3106.9 - 800841 - - - -0.0787 - 2.465 0.24 - 472.8 1 2 0 -0.0001 10 0 0 0 5.91E+07 3.84E+07 - - - 3.3319 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.14545.14545.2 0.00481 14-Aug K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 0.95 11696 14545 2 895.481261 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3107.3 - 631817 - - - 1.0129 - 1.338 0.315 - 170.9 1 2 0 0.0009 8 0 0 0 4.86E+07 5.12E+07 - - - 2.2455 0.9947 230117_WJC_METTL3_WT_vs_EV_F02.14549.14549.2 0.108 12-Jun R.FWETLDR.Y "sp|Q6P1J9|CDC73_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN" 2 965.4607 1.66 11698 14549 2 965.459884 483.7376 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 4.37 3107.8 - 1.45E+06 - - - -0.8255 - 1.315 0.235 - 161.7 1 2 0 -0.0008 7 0 0 0 4.25E+07 2.56E+07 - - - 1.6441 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.14556.14556.2 0.00271 20-Aug K.ILATTPSAVFR[166.11].V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1184.6793 1.93 11703 14556 2 1184.676861 593.3469 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3108.5 - 506100 - - - -2.0411 - 1.619 0.396 - 169.5 1 2 0 -0.0024 11 0 0 0 5.76E+07 2.99E+07 - - - 3.2685 0.9897 230117_WJC_METTL3_WT_vs_EV_F02.14558.14558.2 0.695 14-Jul R.ELVITIAR.E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 913.5597 1.23 11704 14558 2 913.558566 457.7871 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3108.7 - 2.21E+07 - - - -1.2052 - 1.514 0.134 - 283.8 1 2 0 -0.0011 8 0 0 0 4.14E+08 3.35E+08 - - - 1.2813 1 230117_WJC_METTL3_WT_vs_EV_F02.14574.14574.3 1.75E-07 15/128 R.SDSPVPTAPTSGGPKPSTASAVPELATDPELEK.K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3232.5987 5.91 11709 14574 3 3232.605688 1078.5402 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3110.9 - 806532 - - - 2.1623 - 2.817 0.582 - 101.3 1 2 0 0.007 33 0 0 0 1.65E+07 2.79E+06 - - - 7.4095 0.9916 230117_WJC_METTL3_WT_vs_EV_F02.14576.14576.2 0.491 14-Aug R.GLVGEIIK.R "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 827.5117 1.02 11710 14576 2 827.511237 414.7631 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6 3111.1 - 6.96E+06 - - - -0.5039 - 1.253 0.187 - 210.1 1 2 0 -0.0004 8 0 0 0 4.85E+09 4.74E+09 - - - 1.1023 0.8648 230117_WJC_METTL3_WT_vs_EV_F02.14578.14578.2 0.118 16-Jul R.GTSSGFGR[166.11]P.Q "sp|Q5TIE3|VW5B1_HUMAN,tr|H0YED8|H0YED8_HUMAN" 2 874.4172 0.01 11712 14578 2 874.418165 438.2159 von Willebrand factor A domain-containing protein 5B1 OS=Homo sapiens OX=9606 GN=VWA5B1 PE=1 SV=2 9.75 3111.3 - 1.05E+06 - - - 1.0464 - 1.142 0.315 - 112.9 1 1 0 0.0009 9 0 0 0 8.28E+05 9.02E+07 - - - 1.7514 0.8976 230117_WJC_METTL3_WT_vs_EV_F02.14581.14581.2 6.54 12-Jun R.LILQIGR.G "sp|Q9NP73|ALG13_HUMAN,tr|A0A096LNJ4|A0A096LNJ4_HUMAN,tr|A0A087WX43|A0A087WX43_HUMAN,tr|A0A087WTT9|A0A087WTT9_HUMAN,tr|D6RE84|D6RE84_HUMAN,tr|A0A096LP10|A0A096LP10_HUMAN,tr|A0A096LNL2|A0A096LNL2_HUMAN,tr|A0A1B0GVW6|A0A1B0GVW6_HUMAN" 8 811.528 1.64 11713 14581 2 811.526915 406.7713 Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 OS=Homo sapiens OX=9606 GN=ALG13 PE=1 SV=2 9.75 3111.7 - 632421 - - - -1.3037 - 0.958 0.103 - 79.7 1 2 0 -0.0011 7 0 0 0 2.12E+07 1.29E+07 - - - -0.3345 0.9951 230117_WJC_METTL3_WT_vs_EV_F02.14584.14584.2 0.152 12-Jun R.FPYYLSR.H sp|Q8NAF0|ZN579_HUMAN 1 944.4756 1.57 11715 14584 2 944.476489 473.2451 Zinc finger protein 579 OS=Homo sapiens OX=9606 GN=ZNF579 PE=1 SV=2 8.59 3112.1 - 491296 - - - 0.9381 - 1.141 0.211 - 97.9 1 2 0 0.0009 7 0 0 0 3.29E+07 2.10E+07 - - - 1.0171 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14585.14585.2 0.15 16-Nov R.GSPLLIGVR[166.11].S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 920.5683 1.49 11716 14585 2 920.56813 461.2914 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3112.1 - 4.75E+06 - - - -0.1543 - 2.211 0.415 - 579.3 1 2 0 -0.0001 9 0 0 0 2.00E+08 1.34E+08 - - - 4.4016 0.9952 230117_WJC_METTL3_WT_vs_EV_F02.14593.14593.2 5.59 12-Jun R.ELLEIVK[136.11].K sp|P31153|METK2_HUMAN 1 850.5255 1.27 11722 14593 2 850.52526 426.27 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 4.53 3113.1 - 847193 - - - -0.3057 - 1.543 0.141 - 123.7 1 2 0 -0.0003 7 0 0 0 6.80E+07 5.34E+07 - - - 1.4566 0.9357 230117_WJC_METTL3_WT_vs_EV_F02.14594.14594.2 0.284 12-Sep S.PLLIGVR[166.11].S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,sp|Q9UP38|FZD1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 6 776.5148 1.45 11723 14594 2 776.515956 389.2647 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 10.18 3113.3 - 475682 - - - 1.5157 - 1.946 0.189 - 228.1 1 1 0 0.0012 7 0 0 0 1.52E+07 1.05E+07 - - - 2.5461 0.9449 230117_WJC_METTL3_WT_vs_EV_F02.14598.14598.2 0.0417 12-Jun R.IFFVSAK.E "sp|O95140|MFN2_HUMAN,sp|Q8IWA4|MFN1_HUMAN,tr|A0A6Q8PGV8|A0A6Q8PGV8_HUMAN,tr|H7C5H5|H7C5H5_HUMAN,tr|A0A6Q8PFJ4|A0A6Q8PFJ4_HUMAN,tr|A0A6Q8PGA3|A0A6Q8PGA3_HUMAN,tr|A0A6Q8PGS9|A0A6Q8PGS9_HUMAN" 7 810.464 0.65 11725 14598 2 810.459606 406.2393 Mitofusin-2 OS=Homo sapiens OX=9606 GN=MFN2 PE=1 SV=3 8.75 3113.7 - 803418 - - - -5.392 - 1.379 0.274 - 99.3 1 2 0 -0.0044 7 0 0 0 1.63E+07 2.51E+07 - - - 2.0816 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.14599.14599.2 0.0159 16-Jun R.VYSYALALK.H "sp|Q9UKK9|NUDT5_HUMAN,tr|A6NFX8|A6NFX8_HUMAN" 2 1026.575 3.85 11726 14599 2 1026.573991 514.2948 ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1 8.47 3113.9 - 1.40E+06 - - - -0.9663 - 1.334 0.286 - 93.5 1 2 0 -0.001 9 0 0 0 3.94E+07 1.02E+07 - - - 1.9868 0.979 230117_WJC_METTL3_WT_vs_EV_F02.14602.14602.2 0.0351 12-Jun K.ELLPEIR[166.11].E "sp|P49321|NASP_HUMAN,tr|H0YDS9|H0YDS9_HUMAN,tr|Q5T624|Q5T624_HUMAN,tr|H0YF33|H0YF33_HUMAN,tr|E9PRH9|E9PRH9_HUMAN" 5 878.5101 3.16 11727 14602 2 878.510166 440.2623 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 4.53 3114.3 - 456520 - - - 0.0888 - 1.39 0.015 - 136.2 1 2 0 0.0001 7 0 0 0 7.45E+07 2.36E+07 - - - 0.1952 0.996 230117_WJC_METTL3_WT_vs_EV_F02.14607.14607.2 0.0886 12-Jun R.IFFVSAK[136.11].E "sp|O95140|MFN2_HUMAN,sp|Q8IWA4|MFN1_HUMAN,tr|A0A6Q8PGV8|A0A6Q8PGV8_HUMAN,tr|H7C5H5|H7C5H5_HUMAN,tr|A0A6Q8PFJ4|A0A6Q8PFJ4_HUMAN,tr|A0A6Q8PGA3|A0A6Q8PGA3_HUMAN,tr|A0A6Q8PGS9|A0A6Q8PGS9_HUMAN" 7 818.4782 1.05 11729 14607 2 818.477445 410.2464 Mitofusin-2 OS=Homo sapiens OX=9606 GN=MFN2 PE=1 SV=3 8.75 3114.9 - 434337 - - - -0.8931 - 1.438 0.235 - 101.6 1 2 0 -0.0007 7 0 0 0 3.72E+07 3.52E+07 - - - 1.9275 0.9943 230117_WJC_METTL3_WT_vs_EV_F02.14609.14609.2 0.162 14-Jul K.LITDEFVK.Q "sp|Q12816|TROP_HUMAN,sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN,tr|A0A087X070|A0A087X070_HUMAN,tr|G5E9N2|G5E9N2_HUMAN" 6 963.5277 1.17 11730 14609 2 963.528158 482.7711 Trophinin OS=Homo sapiens OX=9606 GN=TRO PE=1 SV=3 4.37 3115.2 - 1.02E+06 - - - 0.4774 - 1.235 0.18 - 106.7 1 2 0 0.0005 8 0 0 0 3.16E+08 2.69E+08 - - - 1.0069 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.14611.14611.2 0.000615 16-Aug K.NFITAEELR.R "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1091.5611 1.94 11731 14611 2 1091.559395 546.7878 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.53 3115.5 - 311383 - - - -1.584 - 1.876 0.407 - 172.8 1 2 0 -0.0017 9 0 0 0 6.62E+06 3.42E+06 - - - 3.8667 0.8742 230117_WJC_METTL3_WT_vs_EV_F02.14614.14614.2 1.62 18-Jun K.SVGGAC[160.03]VLVA.- "sp|P46776|RL27A_HUMAN,tr|E9PLX7|E9PLX7_HUMAN,tr|E9PJD9|E9PJD9_HUMAN" 3 931.4797 - 11732 14614 2 931.478427 466.7471 60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2 5.24 3115.9 - 4.54E+06 - - - -1.3699 - 0.854 0.128 - 69.7 1 2 0 -0.0013 10 0 0 0 - - - - - -0.4545 0.9964 230117_WJC_METTL3_WT_vs_EV_F02.14621.14621.2 0.155 12-Sep R.TLDTFLR.S sp|Q96SK2|TM209_HUMAN 1 864.4705 1.6 11737 14621 2 864.469663 433.2425 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 5.5 3116.7 - 1.74E+06 - - - -0.989 - 1.435 0.259 - 261.3 1 2 0 -0.0009 7 0 0 0 5.11E+07 3.19E+07 - - - 2.0981 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.14622.14622.2 0.0559 14-Sep K.LITDEFVK[136.11].Q "sp|Q12816|TROP_HUMAN,sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN,tr|A0A087X070|A0A087X070_HUMAN,tr|G5E9N2|G5E9N2_HUMAN" 6 971.5419 1.17 11738 14622 2 971.542696 486.7782 Trophinin OS=Homo sapiens OX=9606 GN=TRO PE=1 SV=3 4.37 3116.8 - 1.73E+06 - - - 0.8214 - 1.469 0.262 - 174.8 1 2 0 0.0008 8 0 0 0 3.16E+08 2.69E+08 - - - 2.1358 0.9388 230117_WJC_METTL3_WT_vs_EV_F02.14625.14625.2 0.435 16-Jun K.LVTEPLVLK[136.11].S sp|O43896|KIF1C_HUMAN 1 1018.6518 1.09 11741 14625 2 1018.657152 510.3332 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 6 3117.2 - 706904 - - - 5.2707 - 1.262 0.157 - 104.1 3 2 0 0.0054 9 0 0 0 3.46E+07 3.18E+07 - - - 0.659 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.14628.14628.2 0.0163 16-Aug K.EGLVMVEVR[166.11].K sp|Q7KZF4|SND1_HUMAN 1 1040.5564 67.66 11744 14628 2 1040.555224 521.2855 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.53 3117.6 - 183748 - - - -1.1167 - 1.485 0.282 - 134.1 1 2 0 -0.0012 9 0 0 0 5.58E+08 8.25E+06 - - - 2.2674 0.9741 230117_WJC_METTL3_WT_vs_EV_F02.14630.14630.2 0.904 14-Jul R.GLVGEIIK[136.11].R "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 835.5259 1.02 11745 14630 2 835.525975 418.7702 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6 3117.8 - 8.08E+07 - - - 0.1448 - 1.267 0.038 - 131.3 1 2 0 0.0001 8 0 0 0 4.85E+09 4.74E+09 - - - 0.0354 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14633.14633.2 0.025 16-Oct K.FVGNIYTLK[136.11].C "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1061.6001 1.99 11747 14633 2 1061.601887 531.8073 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3118.1 - 1.02E+06 - - - 1.7003 - 1.634 0.445 - 239.7 1 2 0 0.0018 9 0 0 0 1.12E+08 5.63E+07 - - - 3.7478 0.996 230117_WJC_METTL3_WT_vs_EV_F02.14639.14639.2 0.577 12-Sep R.TLDTFLR[166.11].S sp|Q96SK2|TM209_HUMAN 1 874.4788 1.61 11751 14639 2 874.478469 438.2467 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 5.5 3118.9 - 1.06E+06 - - - -0.3648 - 1.307 0.236 - 251.9 1 2 0 -0.0003 7 0 0 0 5.11E+07 3.18E+07 - - - 1.6323 0.865 230117_WJC_METTL3_WT_vs_EV_F02.14640.14640.2 4.97 12-Jun R.TVYLFDR[166.11].R sp|A6NHR9|SMHD1_HUMAN 1 922.4788 0.81 11752 14640 2 922.478184 462.2467 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 5.5 3119.1 - 905966 - - - -0.6548 - 0.925 0.057 - 148.8 1 2 0 -0.0006 7 0 0 0 1.74E+07 2.14E+07 - - - -0.7852 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.14645.14645.2 0.00308 16-Aug R.MGPNIYELR[166.11].T "sp|Q9BPW8|NIPS1_HUMAN,tr|C9JDV8|C9JDV8_HUMAN,tr|H7C2U6|H7C2U6_HUMAN" 3 1101.5516 1.43 11755 14645 2 1101.551581 551.7831 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.75 3119.7 - 1.12E+06 - - - -0.049 - 1.51 0.434 - 144.1 1 2 0 -0.0001 9 0 0 0 4.68E+07 3.27E+07 - - - 3.4388 0.9764 230117_WJC_METTL3_WT_vs_EV_F02.14646.14646.2 0.245 12-Aug R.LMDLLQK[136.11].K sp|Q9UJV9|DDX41_HUMAN 1 867.4979 0.95 11756 14646 2 867.497933 434.7562 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.84 3119.8 - 3.16E+06 - - - 0.0092 - 1.412 0.001 - 165.7 1 2 0 0 7 0 0 0 6.72E+07 7.06E+07 - - - 0.1416 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.14647.14647.2 0.00962 16-Jul K.LVTEPLVLK.S sp|O43896|KIF1C_HUMAN 1 1010.6376 0.79 11757 14647 2 1010.637372 506.3261 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 6 3119.8 - 1.99E+06 - - - -0.2088 - 1.383 0.364 - 108 1 2 0 -0.0002 9 0 0 0 3.55E+07 4.49E+07 - - - 2.6675 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.14648.14648.2 0.0345 18-Nov R.VVVDALSGLK.G "sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|F8WCN3|F8WCN3_HUMAN" 3 999.5964 1.74 11758 14648 2 999.595782 500.8055 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 5.81 3119.9 - 1.01E+06 - - - -0.6653 - 2.118 0.37 - 350.3 1 2 0 -0.0007 10 0 0 0 9.25E+07 5.32E+07 - - - 3.8684 0.9489 230117_WJC_METTL3_WT_vs_EV_F02.14669.14669.2 3.74 14-Jun K.FYGELALK.K "sp|P78527|PRKDC_HUMAN,tr|F5GX40|F5GX40_HUMAN" 2 939.5066 1.15 11768 14669 2 939.506623 470.7606 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 3122.6 - 639287 - - - 0.0575 - 1.088 0.043 - 72.5 1 2 0 0.0001 8 0 0 0 4.17E+07 3.62E+07 - - - -0.387 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.14670.14670.2 0.0186 14-Jun R.EFADFEYR[166.11].K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1085.4693 1.19 11769 14670 2 1085.471869 543.7419 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3122.8 - 313385 - - - 2.3253 - 1.445 0.434 - 113.6 1 2 0 0.0025 8 0 0 0 1.27E+07 1.07E+07 - - - 3.3559 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.14673.14673.2 0.000157 14-Jul R.EFADFEYR.K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1075.4611 1.19 11770 14673 2 1075.461384 538.7378 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3123.1 - 406551 - - - 0.2873 - 1.665 0.522 - 225.6 1 2 0 0.0003 8 0 0 0 1.27E+07 1.07E+07 - - - 4.434 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.14675.14675.2 0.00342 18-Oct R.VVVDALSGLK[136.11].G "sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|F8WCN3|F8WCN3_HUMAN" 3 1007.6106 1.73 11771 14675 2 1007.615276 504.8126 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 5.81 3123.4 - 1.22E+06 - - - 4.594 - 2.13 0.452 - 307.1 1 2 0 0.0046 10 0 0 0 9.22E+07 5.32E+07 - - - 4.4886 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.14681.14681.2 0.168 16-Oct K.LGIIGVVNR.S "sp|O00429|DNM1L_HUMAN,tr|F8VZ52|F8VZ52_HUMAN" 2 939.5866 1.46 11775 14681 2 939.58752 470.8006 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 9.75 3124.1 - 1.23E+06 - - - 1.0313 - 1.851 0.335 - 222.6 1 2 0 0.001 9 0 0 0 6.05E+07 4.15E+07 - - - 3.2963 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.14685.14685.2 0.0959 14-Sep K.IIYIAPMR.S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 975.5576 1.35 11777 14685 2 975.558088 488.7861 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 3124.6 - 2.63E+06 - - - 0.5423 - 1.538 0.259 - 247.6 1 2 0 0.0005 8 0 0 0 9.22E+07 6.81E+07 - - - 2.2521 0.9957 230117_WJC_METTL3_WT_vs_EV_F02.14695.14695.2 0.0929 12-Jul R.YIELLTR.S sp|P15924|DESP_HUMAN 1 906.5175 13.46 11783 14695 2 906.517748 454.266 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 3125.9 - 1.37E+07 - - - 0.3089 - 1.239 0.211 - 211.4 1 2 0 0.0003 7 0 0 0 2.03E+08 1.51E+07 - - - 1.2784 0.995 230117_WJC_METTL3_WT_vs_EV_F02.14701.14701.2 0.504 12-Jul R.TMLLLSR[166.11].S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 842.4923 1.84 11787 14701 2 842.491661 422.2534 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.41 3126.6 - 1.71E+06 - - - -0.7929 - 1.389 0.215 - 197.3 1 2 0 -0.0007 7 0 0 0 7.55E+07 4.10E+07 - - - 1.6699 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.14710.14710.2 0.012 14-Jun K.LTPLLSVR.E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 897.5648 0.98 11794 14710 2 897.566275 449.7897 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3127.5 - 1.26E+06 - - - 1.6957 - 1.398 0.189 - 115.7 1 2 0 0.0015 8 0 0 0 2.41E+08 2.46E+08 - - - 1.4469 0.999 230117_WJC_METTL3_WT_vs_EV_F02.14711.14711.2 0.968 16-Aug K.LGIIGVVNR[166.11].S "sp|O00429|DNM1L_HUMAN,tr|F8VZ52|F8VZ52_HUMAN" 2 949.5948 1.46 11795 14711 2 949.59688 475.8047 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 9.75 3127.6 - 2.28E+06 - - - 2.1683 - 1.725 0.259 - 141.8 1 2 0 0.0021 9 0 0 0 6.05E+07 4.15E+07 - - - 2.5307 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.14714.14714.2 0.26 14-Aug K.IIYIAPMR[166.11].S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 985.5658 1.35 11797 14714 2 985.567453 493.7902 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 3127.9 - 1.40E+06 - - - 1.6478 - 1.572 0.214 - 213.3 1 2 0 0.0016 8 0 0 0 9.22E+07 6.82E+07 - - - 1.9854 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.14718.14718.2 0.00096 14-Sep R.LGYPVLVR[166.11].A "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 925.5625 2.11 11800 14718 2 925.56512 463.7885 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 8.75 3128.4 - 3.03E+06 - - - 2.8761 - 1.73 0.41 - 242.5 1 2 0 0.0027 8 0 0 0 1.75E+08 8.31E+07 - - - 3.7215 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.14720.14720.2 0.0261 18-Sep R.AGLTEPVLIR[166.11].L sp|Q8TDD1|DDX54_HUMAN 1 1077.6422 0.45 11802 14720 2 1077.644467 539.8284 ATP-dependent RNA helicase DDX54 OS=Homo sapiens OX=9606 GN=DDX54 PE=1 SV=2 6.05 3128.6 - 488000 - - - 2.1361 - 1.506 0.296 - 176.5 1 2 0 0.0023 10 0 0 0 7.77E+06 1.73E+07 - - - 2.3695 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.14723.14723.2 0.00157 12-Sep R.TMLLLSR.S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 832.4841 1.85 11803 14723 2 832.484613 417.2493 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.41 3129 - 3.22E+06 - - - 0.6655 - 1.77 0.253 - 447.8 1 2 0 0.0006 7 0 0 0 7.62E+07 4.12E+07 - - - 2.7187 0.9816 230117_WJC_METTL3_WT_vs_EV_F02.14725.14725.2 3.72 12-Aug K.IGIEIIK.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 784.5058 2.14 11805 14725 2 784.507985 393.2602 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3129.2 - 2.41E+06 - - - 2.7329 - 1.371 0.043 - 145.8 1 2 0 0.0021 7 0 0 0 1.96E+07 9.19E+06 - - - 0.3577 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.14727.14727.2 0.0495 12-Jul K.VTFLITR[166.11].L "sp|A6ZKI3|RTL8C_HUMAN,sp|Q9BWD3|RTL8A_HUMAN,sp|Q17RB0|RTL8B_HUMAN" 3 858.5203 2.18 11807 14727 2 858.522259 430.2674 Retrotransposon Gag-like protein 8C OS=Homo sapiens OX=9606 GN=RTL8C PE=1 SV=1 9.72 3129.5 - 647382 - - - 2.3296 - 1.405 0.272 - 171.2 1 2 0 0.002 7 0 0 0 7.27E+07 3.33E+07 - - - 2.1268 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14728.14728.2 0.000648 14-Jul K.LLESDYFR.Y "sp|Q96HE7|ERO1A_HUMAN,tr|G3V503|G3V503_HUMAN,tr|G3V3E6|G3V3E6_HUMAN" 3 1041.5131 2.21 11808 14728 2 1041.514423 521.7638 ERO1-like protein alpha OS=Homo sapiens OX=9606 GN=ERO1A PE=1 SV=2 4.37 3129.6 - 408894 - - - 1.2597 - 1.4 0.453 - 132.4 1 2 0 0.0013 8 0 0 0 8.05E+06 3.64E+06 - - - 3.4012 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.14733.14733.2 2.16 12-Aug K.LVLILNK[136.11].S "sp|Q9BVP2|GNL3_HUMAN,sp|Q96RW7|HMCN1_HUMAN" 2 819.5673 0.97 11811 14733 2 819.568167 410.7909 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.75 3130.2 - 1.39E+06 - - - 1.0274 - 1.553 0.145 - 206.7 1 2 0 0.0008 7 0 0 0 5.90E+07 6.08E+07 - - - 1.5065 0.9691 230117_WJC_METTL3_WT_vs_EV_F02.14734.14734.2 4.47 12-Jun K.LVLILNK.S "sp|Q9BVP2|GNL3_HUMAN,sp|Q96RW7|HMCN1_HUMAN" 2 811.5531 0.97 11812 14734 2 811.554172 406.7838 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.75 3130.3 - 1.32E+06 - - - 1.2901 - 1.288 0.001 - 122.3 2 2 0 0.001 7 0 0 0 5.90E+07 6.08E+07 - - - -0.2845 0.9839 230117_WJC_METTL3_WT_vs_EV_F02.14746.14746.2 0.04 14-Jul K.LTPLLSVR[166.11].E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 907.573 0.98 11820 14746 2 907.574819 454.7938 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3131.8 - 5.89E+06 - - - 1.9789 - 1.243 0.07 - 215.5 1 2 0 0.0018 8 0 0 0 2.41E+08 2.46E+08 - - - 0.2135 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.14748.14748.2 0.00197 12-Sep K.VSTVFWK[136.11].S sp|Q14152|EIF3A_HUMAN 1 873.484 0.44 11822 14748 2 873.486677 437.7493 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.72 3132 - 1.22E+06 - - - 3.0762 - 1.67 0.317 - 237.6 1 2 0 0.0027 7 0 0 0 2.34E+07 5.32E+07 - - - 3.0064 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.14755.14755.2 0.000683 12-Aug K.FDLMYAK.R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 886.4259 3.25 11827 14755 2 886.42742 444.2202 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3132.9 - 2.25E+06 - - - 1.7418 - 1.655 0.357 - 211.3 1 2 0 0.0015 7 0 0 0 1.00E+09 3.08E+08 - - - 3.2736 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14765.14765.2 0.00791 18-Sep R.VLLGEGVLTK[136.11].E "sp|Q96S99|PKHF1_HUMAN,sp|Q9H8W4|PKHF2_HUMAN,tr|K7ELB8|K7ELB8_HUMAN,tr|K7EIX0|K7EIX0_HUMAN" 4 1035.6419 0.73 11835 14765 2 1035.642142 518.8282 Pleckstrin homology domain-containing family F member 1 OS=Homo sapiens OX=9606 GN=PLEKHF1 PE=1 SV=3 5.97 3133.9 - 1.64E+06 - - - 0.1883 - 1.887 0.447 - 210.8 1 2 0 0.0002 10 0 0 0 3.18E+07 4.36E+07 - - - 4.1149 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.14769.14769.2 0.00423 16-Sep K.GFVTADMIR.E sp|Q9UHQ9|NB5R1_HUMAN 1 1008.5063 1.9 11839 14769 2 1008.508978 505.2604 NADH-cytochrome b5 reductase 1 OS=Homo sapiens OX=9606 GN=CYB5R1 PE=1 SV=1 5.84 3134.3 - 457735 - - - 2.704 - 1.778 0.412 - 250.9 1 2 0 0.0027 9 0 0 0 1.22E+07 6.46E+06 - - - 3.7481 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.14779.14779.2 0.799 12-Jul R.AVTIFIR.G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 818.5014 4.34 11845 14779 2 818.502582 410.258 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3135.5 - 3.72E+06 - - - 1.4148 - 1.53 0.14 - 225.2 1 2 0 0.0012 7 0 0 0 2.59E+09 5.98E+08 - - - 1.4222 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.14780.14780.2 0.0151 12-Aug R.FC[160.03]DVLLR.V "sp|Q9HBE1|PATZ1_HUMAN,tr|B1ARF3|B1ARF3_HUMAN" 2 921.4742 0.36 11846 14780 2 921.475138 461.7444 "POZ-, AT hook-, and zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=PATZ1 PE=1 SV=1" 5.83 3135.7 - 404916 - - - 0.993 - 1.418 0.288 - 234.4 1 2 0 0.0009 7 0 0 0 1.93E+07 5.32E+07 - - - 2.2745 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.14786.14786.2 3.5 12-Jun R.LLC[160.03]NFMR.Q "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN,tr|B4DEV8|B4DEV8_HUMAN" 3 952.4623 0.98 11849 14786 2 952.463232 477.2384 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.25 3136.4 - 820030 - - - 1.0016 - 1.201 0.256 - 99.2 1 2 0 0.001 7 0 0 0 3.15E+07 3.21E+07 - - - 1.5119 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.14788.14788.2 0.00202 12-Jul K.FDLMYAK[136.11].R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 894.4401 3.25 11850 14788 2 894.440319 448.2273 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3136.7 - 5.78E+06 - - - 0.2717 - 1.432 0.233 - 143.7 1 2 0 0.0002 7 0 0 0 1.00E+09 3.08E+08 - - - 1.8996 0.9893 230117_WJC_METTL3_WT_vs_EV_F02.14790.14790.2 0.468 12-Aug R.VAFVNFR.R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 851.4654 1.14 11851 14790 2 851.466833 426.74 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 9.72 3136.9 - 4.67E+06 - - - 1.7147 - 1.337 0.066 - 241.3 1 2 0 0.0015 7 0 0 0 1.22E+08 1.08E+08 - - - 0.4483 0.9942 230117_WJC_METTL3_WT_vs_EV_F02.14807.14807.2 0.152 14-Jul R.LYELDGLR[166.11].E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 987.5265 2.83 11861 14807 2 987.524075 494.7705 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3139 - 894244 - - - -2.4212 - 1.512 0.306 - 161.6 1 2 0 -0.0024 8 0 0 0 6.83E+08 2.41E+08 - - - 2.5473 0.9873 230117_WJC_METTL3_WT_vs_EV_F02.14808.14808.2 0.584 16-Jul K.LISYSYMVR[166.11].G sp|P07099|HYEP_HUMAN 1 1140.5877 1.11 11862 14808 2 1140.588807 571.3011 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 8.59 3139.1 - 402614 - - - 0.9828 - 1.195 0.104 - 119.7 1 2 0 0.0011 9 0 0 0 2.08E+07 1.87E+07 - - - 0.3242 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.14809.14809.2 0.0266 16-Aug K.IPFASLASR[166.11].L sp|P35573|GDE_HUMAN 1 970.5475 1.48 11863 14809 2 970.545949 486.281 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3139.2 - 827815 - - - -1.6352 - 1.427 0.318 - 104.7 1 2 0 -0.0016 9 0 0 0 2.77E+07 1.87E+07 - - - 2.4179 0.9949 230117_WJC_METTL3_WT_vs_EV_F02.14812.14812.2 0.0202 12-Jul R.ELFVMAR.E "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QSA9|J3QSA9_HUMAN" 4 864.4528 5.32 11864 14812 2 864.452199 433.2337 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 6.1 3139.6 - 3.94E+06 - - - -0.6478 - 1.602 0.141 - 236 1 2 0 -0.0006 7 0 0 0 1.91E+08 3.60E+07 - - - 1.5754 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14823.14823.2 0.00471 16-Sep K.IPFASLASR.L sp|P35573|GDE_HUMAN 1 960.5393 0.31 11871 14823 2 960.54003 481.2769 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3141 - 1.32E+06 - - - 0.7954 - 1.742 0.402 - 226.5 1 2 0 0.0008 9 0 0 0 2.85E+07 9.12E+07 - - - 3.6157 0.9899 230117_WJC_METTL3_WT_vs_EV_F02.14827.14827.2 0.357 12-Jun R.AVTIFIR[166.11].G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 828.5097 4.32 11874 14827 2 828.509555 415.2621 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3141.4 - 8.40E+06 - - - -0.1678 - 1.443 0.082 - 145.7 1 2 0 -0.0001 7 0 0 0 2.60E+09 6.00E+08 - - - 0.8086 1 230117_WJC_METTL3_WT_vs_EV_F02.14830.14830.2 2.36E-06 22-Nov K.FAQALGLTEAVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1254.7063 1.02 11876 14830 2 1254.705415 628.3604 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3141.7 - 718133 - - - -0.7356 - 2.329 0.499 - 398 1 2 0 -0.0009 12 0 0 0 3.13E+07 3.06E+07 - - - 4.9508 0.9921 230117_WJC_METTL3_WT_vs_EV_F02.14847.14847.2 0.0905 12-Jul R.IVFQEFR[166.11].Q "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN" 2 947.5104 0.77 11883 14847 2 947.509613 474.7625 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3144 - 1.86E+06 - - - -0.8538 - 1.357 0.178 - 172 1 2 0 -0.0008 7 0 0 0 1.70E+08 2.21E+08 - - - 1.3227 0.998 230117_WJC_METTL3_WT_vs_EV_F02.14850.14850.2 8.02E-07 13/22 K.FAQALGLTEAVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1246.6921 1.02 11885 14850 2 1246.689098 624.3533 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3144.4 - 1.70E+06 - - - -2.4385 - 2.262 0.41 - 431.8 1 2 0 -0.003 12 0 0 0 3.13E+07 3.06E+07 - - - 4.216 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.14868.14868.2 0.0106 14-Aug R.DAFVYAIK.N "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 925.4909 0.85 11890 14868 2 925.489564 463.7527 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 5.83 3147 - 2.33E+06 - - - -1.4641 - 1.555 0.321 - 281.8 1 2 0 -0.0014 8 0 0 0 1.34E+08 1.58E+08 - - - 2.743 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.14872.14872.2 0.000242 18-Sep K.AYAALAALEK[136.11].L sp|Q12906|ILF3_HUMAN 1 1027.5793 26.06 11892 14872 2 1027.57691 514.7969 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.05 3147.5 - 1.24E+06 - - - -2.3716 - 1.811 0.47 - 221.5 1 2 0 -0.0024 10 0 0 0 2.54E+08 9.75E+06 - - - 4.1694 0.9572 230117_WJC_METTL3_WT_vs_EV_F02.14878.14878.2 1.19 12-Jul K.YLPDIIK.D sp|O15355|PPM1G_HUMAN 1 860.5008 3.64 11895 14878 2 860.498771 431.2577 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 5.83 3148.1 - 1.13E+06 - - - -2.3056 - 1.04 0.21 - 146.4 1 2 0 -0.002 7 0 0 0 1.89E+08 5.20E+07 - - - 0.7157 0.9936 230117_WJC_METTL3_WT_vs_EV_F02.14893.14893.2 0.552 12-Jun K.FLSVLER[166.11].Q sp|P07099|HYEP_HUMAN 1 872.4995 1.06 11902 14893 2 872.499955 437.257 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 6 3150.1 - 2.44E+06 - - - 0.4951 - 1.435 0.116 - 120.3 2 2 0 0.0004 7 0 0 0 7.96E+07 7.53E+07 - - - 0.9075 0.9473 230117_WJC_METTL3_WT_vs_EV_F02.14896.14896.2 0.0923 12-Jul K.LGFEEFK.Y "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 868.4331 2.43 11905 14896 2 868.43128 435.2238 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 3150.3 - 3.30E+06 - - - -2.0612 - 1.093 0.153 - 133.4 1 2 0 -0.0018 7 0 0 0 2.28E+08 9.37E+07 - - - 0.4523 0.9654 230117_WJC_METTL3_WT_vs_EV_F02.14898.14898.2 0.0634 12-Jul K.LGFEEFK[136.11].Y "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 876.4473 2.43 11907 14898 2 876.443968 439.2309 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 3150.6 - 1.36E+06 - - - -3.7675 - 1.556 0.157 - 138.1 1 2 0 -0.0033 7 0 0 0 2.28E+08 9.37E+07 - - - 1.6004 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.14907.14907.2 0.0578 18-Sep R.INEILSNALK.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 3 1113.6394 8.32 11911 14907 2 1113.640371 557.827 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3151.8 - 0 - - - 0.8953 - 1.836 0.28 - 207 1 2 0 0.001 10 0 0 0 2.29E+07 2.76E+06 - - - 2.8047 0.937 230117_WJC_METTL3_WT_vs_EV_F02.14915.14915.2 3.87 12-Jul K.YVLALVK[136.11].K "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 812.5251 1.06 11914 14915 2 812.522761 407.2698 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.59 3153 - 305850 - - - -2.9107 - 1.263 0.124 - 168.6 1 2 0 -0.0024 7 0 0 0 5.36E+07 5.03E+07 - - - 0.6959 0.9949 230117_WJC_METTL3_WT_vs_EV_F02.14918.14918.2 0.21 16-Aug R.ILDSAEFIK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1042.579 0.93 11915 14918 2 1042.577275 522.2968 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3153.4 - 1.98E+06 - - - -1.6661 - 1.663 0.225 - 117.3 1 2 0 -0.0017 9 0 0 0 7.65E+09 8.24E+09 - - - 2.1738 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.14927.14927.2 0.717 16-Oct R.AFSYYGPLR[166.11].T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1082.5425 0.92 11919 14927 2 1082.540043 542.2785 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3154.4 - 1.42E+06 - - - -2.2244 - 2.102 0.33 - 412.7 1 2 0 -0.0024 9 0 0 0 2.95E+08 3.20E+08 - - - 3.6268 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.14929.14929.2 2.87E-05 16-Sep R.AFSYYGPLR.T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1072.5342 0.92 11920 14929 2 1072.530809 537.2744 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3154.6 - 1.34E+06 - - - -3.144 - 1.798 0.521 - 300.2 1 2 0 -0.0034 9 0 0 0 2.95E+08 3.20E+08 - - - 4.5853 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.14930.14930.2 0.0109 20-Oct K.LVLLGESAVGK[136.11].S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1092.6634 1.38 11921 14930 2 1092.663157 547.339 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3154.7 - 1.27E+06 - - - -0.2325 - 1.986 0.303 - 239.4 1 2 0 -0.0003 11 0 0 0 1.40E+08 1.01E+08 - - - 3.135 0.9952 230117_WJC_METTL3_WT_vs_EV_F02.14943.14943.2 0.0599 12-Jul K.YNIMLVR.L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 907.495 8.26 11927 14943 2 907.493088 454.7548 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3156.3 - 2.32E+06 - - - -2.0606 - 1.54 0.282 - 214.9 1 2 0 -0.0019 7 0 0 0 1.74E+09 2.10E+08 - - - 2.4914 0.996 230117_WJC_METTL3_WT_vs_EV_F02.14955.14955.2 0.266 12-Jul K.YNIMLVR[166.11].L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 917.5032 8.26 11933 14955 2 917.502724 459.7589 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3157.9 - 937463 - - - -0.5493 - 1.393 0.221 - 192.1 1 2 0 -0.0005 7 0 0 0 1.74E+09 2.10E+08 - - - 1.7234 0.9915 230117_WJC_METTL3_WT_vs_EV_F02.14968.14968.2 0.0411 20-Aug K.LVLLGESAVGK.S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1084.6492 1.38 11937 14968 2 1084.647433 543.3319 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3159.6 - 5.45E+06 - - - -1.6392 - 1.521 0.203 - 151.1 1 2 0 -0.0018 11 0 0 0 1.40E+08 1.01E+08 - - - 1.6743 0.985 230117_WJC_METTL3_WT_vs_EV_F02.14970.14970.2 0.497 12-Jul R.LNLYELK.E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 891.5066 1.75 11938 14970 2 891.505474 446.7606 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3159.8 - 2.04E+06 - - - -1.2283 - 1.427 0.131 - 137.5 2 2 0 -0.0011 7 0 0 0 1.81E+08 1.03E+08 - - - 1.0004 0.9956 230117_WJC_METTL3_WT_vs_EV_F02.14972.14972.2 0.706 12-Jul R.LNLYELK[136.11].E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 899.5208 1.75 11940 14972 2 899.521208 450.7677 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3160.1 - 1.59E+06 - - - 0.488 - 1.534 0.108 - 134.4 1 2 0 0.0004 7 0 0 0 1.81E+08 1.03E+08 - - - 1.1943 0.999 230117_WJC_METTL3_WT_vs_EV_F02.14979.14979.2 0.00419 16-Aug K.YLPELMAEK[136.11].D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1100.5667 1.14 11941 14979 2 1100.567013 551.2906 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3161.2 - 915258 - - - 0.2544 - 1.552 0.312 - 208.3 1 2 0 0.0003 9 0 0 0 1.01E+08 8.82E+07 - - - 2.617 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.14982.14982.2 0.00179 16-Oct R.ILDSAEFIK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1034.5648 0.93 11942 14982 2 1034.564837 518.2897 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3161.6 - 3.99E+08 - - - 0.0242 - 1.971 0.482 - 221.1 1 2 0 0 9 0 0 0 7.67E+09 8.26E+09 - - - 4.5641 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.14986.14986.2 0.0336 14-Jun R.VMLYPSR[166.11]I.- sp|P18077|RL35A_HUMAN 1 987.5451 0.77 11944 14986 2 987.544931 494.7798 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.72 3162 - 1.23E+06 - - - -0.164 - 1.481 0.321 - 151.9 1 2 0 -0.0002 8 0 0 0 6.06E+07 7.87E+07 - - - 2.5963 0.9969 230117_WJC_METTL3_WT_vs_EV_F02.14992.14992.2 0.0027 16-Aug K.YLPELMAEK.D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1092.5525 1.14 11945 14992 2 1092.549701 547.2835 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3162.9 - 4.11E+06 - - - -2.5921 - 1.496 0.445 - 186.4 1 2 0 -0.0028 9 0 0 0 1.01E+08 8.85E+07 - - - 3.4922 0.9605 230117_WJC_METTL3_WT_vs_EV_F02.15003.15003.2 0.114 12-Jun R.AWYPLGR.L "sp|P46977|STT3A_HUMAN,sp|Q8TCJ2|STT3B_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 5 861.4497 1.6 11951 15003 2 861.447952 431.7321 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 8.79 3164.3 - 323601 - - - -2.0558 - 1.187 0.146 - 128.5 1 2 0 -0.0018 7 0 0 0 1.92E+07 1.20E+07 - - - 0.662 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.15009.15009.2 2.42 14-Jul R.VMLYPSRI.- sp|P18077|RL35A_HUMAN 1 977.5368 0.77 11955 15009 2 977.537207 489.7757 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.72 3165 - 1.05E+06 - - - 0.3928 - 1.487 0.141 - 239.3 1 2 0 0.0004 8 0 0 0 6.06E+07 7.87E+07 - - - 1.2789 0.997 230117_WJC_METTL3_WT_vs_EV_F02.15015.15015.2 0.195 14-Jun K.IEPPGLFR[166.11].G "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|E5RJ95|E5RJ95_HUMAN,tr|E5RIC7|E5RIC7_HUMAN,tr|E5RFS0|E5RFS0_HUMAN" 5 937.5261 0.8 11959 15015 2 937.527961 469.7703 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 6 3165.8 - 2.01E+06 - - - 2.0149 - 1.252 0.238 - 140 1 2 0 0.0019 8 0 0 0 3.87E+07 4.85E+07 - - - 1.4761 0.9446 230117_WJC_METTL3_WT_vs_EV_F02.15018.15018.2 1.06 12-Jul K.LILEYVK.A "sp|Q7L5N1|CSN6_HUMAN,tr|E7EM64|E7EM64_HUMAN" 2 876.5321 1.98 11962 15018 2 876.536452 439.2733 COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1 6 3166.2 - 819068 - - - 5.0164 - 1.347 0.085 - 145.5 1 2 0 0.0044 7 0 0 0 2.55E+07 1.28E+07 - - - 0.6113 0.8589 230117_WJC_METTL3_WT_vs_EV_F02.15023.15023.2 0.453 16-Sep H.VPIILVGNK.A "sp|O75628|REM1_HUMAN,sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,sp|Q8IXI1|MIRO2_HUMAN,sp|P55042|RAD_HUMAN,sp|Q9Y3L5|RAP2C_HUMAN,tr|I3L2C6|I3L2C6_HUMAN,tr|H3BST5|H3BST5_HUMAN,tr|A0A087X2C3|A0A087X2C3_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 16 951.6117 2.14 11965 15023 2 951.61214 476.8131 GTP-binding protein REM 1 OS=Homo sapiens OX=9606 GN=REM1 PE=1 SV=2 8.72 3166.7 - 2.84E+06 - - - 0.4592 - 1.567 0.204 - 252.6 1 1 0 0.0004 9 0 0 0 8.23E+07 3.84E+07 - - - 1.8471 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.15024.15024.2 0.00316 12-Aug K.FADFMVK.D "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 14 856.4153 2.04 11966 15024 2 856.413684 429.2149 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 5.84 3166.8 - 1.35E+06 - - - -1.8998 - 1.599 0.477 - 156.1 1 2 0 -0.0016 7 0 0 0 3.38E+07 1.65E+07 - - - 4.0509 0.996 230117_WJC_METTL3_WT_vs_EV_F02.15030.15030.2 0.0151 12-Jul K.WDPVVLK.N sp|Q9BVJ6|UT14A_HUMAN 1 855.4854 1.29 11970 15030 2 855.484892 428.75 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 5.84 3167.6 - 1.79E+06 - - - -0.6406 - 1.029 0.358 - 144.7 1 2 0 -0.0005 7 0 0 0 7.17E+07 5.54E+07 - - - 1.7756 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.15031.15031.2 0.0319 12-Aug K.WDPVVLK[136.11].N sp|Q9BVJ6|UT14A_HUMAN 1 863.4996 1.35 11971 15031 2 863.498908 432.7571 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 5.84 3167.7 - 1.08E+06 - - - -0.8477 - 1.235 0.291 - 152.1 1 2 0 -0.0007 7 0 0 0 7.17E+07 5.30E+07 - - - 1.8589 0.8918 230117_WJC_METTL3_WT_vs_EV_F02.15042.15042.2 0.673 14-Sep R.PIVTVWER[166.11].E "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EQR8|K7EQR8_HUMAN" 3 1008.5632 5.89 11980 15042 2 1008.564226 505.2889 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 6.43 3168.9 - 834801 - - - 1.0312 - 1.603 0.206 - 310.4 1 1 0 0.001 8 0 0 0 2.53E+08 4.29E+07 - - - 1.9853 0.9933 230117_WJC_METTL3_WT_vs_EV_F02.15044.15044.2 5.66E-06 20-Dec R.MGAGMGFGLER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1134.519 2.01 11982 15044 2 1134.513724 568.2668 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 3169.2 - 489334 - - - -4.6108 - 2.034 0.483 - 447.4 1 2 0 -0.0052 11 0 0 0 4.62E+07 2.30E+07 - - - 4.5275 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.15059.15059.2 0.0772 16-Jul R.ILDSAEFIK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1034.5648 0.93 11991 15059 2 1034.565242 518.2897 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3171.1 - 7.30E+06 - - - 0.4156 - 1.459 0.364 - 102.1 1 2 0 0.0004 9 0 0 0 7.67E+09 8.26E+09 - - - 2.8222 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15060.15060.2 0.0202 14-Sep R.LLEIVSYK.L "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 963.5641 1.1 11992 15060 2 963.565891 482.7893 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6 3171.3 - 750416 - - - 1.8753 - 1.805 0.363 - 234.1 1 2 0 0.0018 8 0 0 0 8.21E+07 7.48E+07 - - - 3.5027 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.15066.15066.2 0.0936 12-Jul K.MDLLLTK[136.11].T "sp|Q6P3W7|SCYL2_HUMAN,tr|H0YIK6|H0YIK6_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 840.487 0.81 11996 15066 2 840.486874 421.2508 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.59 3172 - 1.61E+06 - - - -0.1808 - 1.515 0.212 - 159.9 1 2 0 -0.0002 7 0 0 0 5.75E+07 7.14E+07 - - - 1.9231 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15072.15072.2 0.0015 14-Aug R.VWC[160.03]VASLR.G "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 989.5117 0.74 12000 15072 2 989.513124 495.7631 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 8.22 3172.8 - 898502 - - - 1.4684 - 1.644 0.405 - 229 1 2 0 0.0015 8 0 0 0 1.96E+07 2.67E+07 - - - 3.5312 1 230117_WJC_METTL3_WT_vs_EV_F02.15073.15073.2 3.71E-07 13/28 R.NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1656.8459 6.06 12001 15073 2 1656.850546 829.4302 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3172.9 - 196337 - - - 2.8023 - 2.681 0.544 - 356.1 1 2 0 0.0046 15 0 0 0 2.77E+07 4.57E+06 - - - 5.4821 0.958 230117_WJC_METTL3_WT_vs_EV_F02.15079.15079.2 0.933 12-Jun R.DLGAYLR.Q "sp|Q9BRT2|UQCC2_HUMAN,tr|Q5TAQ0|Q5TAQ0_HUMAN,tr|V5IRT4|V5IRT4_HUMAN" 3 806.4287 0.63 12005 15079 2 806.432341 404.2216 Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1 5.84 3173.6 - 970870 - - - 4.5733 - 1.171 0.144 - 93.7 1 2 0 0.0037 7 0 0 0 1.14E+07 1.81E+07 - - - 0.6036 0.995 230117_WJC_METTL3_WT_vs_EV_F02.15083.15083.2 0.541 12-Aug R.LIVDVIR.F "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 826.5276 0.96 12009 15083 2 826.527287 414.2711 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.84 3174.1 - 818732 - - - -0.4259 - 1.475 0.164 - 209.3 1 2 0 -0.0004 7 0 0 0 7.37E+07 7.65E+07 - - - 1.4837 0.9585 230117_WJC_METTL3_WT_vs_EV_F02.15084.15084.2 1.13 14-Aug K.GAIEVLIR.E "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 869.5335 1.1 12010 15084 2 869.53893 435.774 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 6 3174.2 - 345840 - - - 6.2999 - 1.524 0.162 - 165 1 2 0 0.0055 8 0 0 0 4.18E+07 3.81E+07 - - - 1.5065 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.15089.15089.2 2.56E-06 14-Oct R.VGEIVVFR.L "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 917.5335 2.26 12013 15089 2 917.534543 459.774 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.97 3174.8 - 3.82E+06 - - - 1.1891 - 2.154 0.407 - 424.7 1 2 0 0.0011 8 0 0 0 5.69E+07 2.52E+07 - - - 4.361 0.998 230117_WJC_METTL3_WT_vs_EV_F02.15090.15090.2 0.0818 16-Jul R.LLLPTPTVK.Q "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 980.627 2.43 12014 15090 2 980.629461 491.3208 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 3174.9 - 490389 - - - 2.4913 - 1.366 0.279 - 124.3 1 2 0 0.0024 9 0 0 0 4.15E+08 1.70E+08 - - - 2.0032 1 230117_WJC_METTL3_WT_vs_EV_F02.15095.15095.2 0.00104 13/28 R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 9.22 12019 15095 2 1646.835211 824.4261 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3175.6 - 231514 - - - -1.4707 - 2.571 0.507 - 510.9 1 2 0 -0.0024 15 0 0 0 3.83E+07 4.16E+06 - - - 5.1065 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.15099.15099.2 0.00182 16-Sep K.ELGVGIALR.K sp|Q01469|FABP5_HUMAN 1 926.5549 12.59 12021 15099 2 926.555704 464.2847 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 6.1 3176.1 - 7.46E+06 - - - 0.8505 - 1.811 0.426 - 364.8 1 2 0 0.0008 9 0 0 0 1.43E+08 1.13E+07 - - - 3.9053 0.9941 230117_WJC_METTL3_WT_vs_EV_F02.15100.15100.2 0.0495 12-Apr K.LVPGLFK[136.11].N "sp|P35226|BMI1_HUMAN,sp|P35227|PCGF2_HUMAN,tr|Q5T8Z6|Q5T8Z6_HUMAN,tr|A0A087X259|A0A087X259_HUMAN,tr|J3KT13|J3KT13_HUMAN,tr|R4GMX3|R4GMX3_HUMAN,tr|Q5T8Z4|Q5T8Z4_HUMAN" 7 780.4989 1.31 12022 15100 2 780.499229 391.2567 Polycomb complex protein BMI-1 OS=Homo sapiens OX=9606 GN=BMI1 PE=1 SV=2 8.75 3176.2 - 1.43E+06 - - - 0.4074 - 1.038 0.267 - 50.3 2 2 0 0.0003 7 0 0 0 5.41E+07 4.14E+07 - - - 0.9967 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.15102.15102.2 1.11 14-Aug K.GAIEVLIR[166.11].E "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 879.5417 1.12 12024 15102 2 879.542348 440.7781 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 6 3176.4 - 1.30E+06 - - - 0.7117 - 1.716 0.143 - 185.1 1 2 0 0.0006 8 0 0 0 4.18E+07 3.75E+07 - - - 1.7256 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.15103.15103.2 0.0154 16-Sep K.ANPALYVLR[166.11].E sp|Q6P2Q9|PRP8_HUMAN 1 1025.5897 1.36 12025 15103 2 1025.591241 513.8021 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.79 3176.5 - 920263 - - - 1.4684 - 1.466 0.296 - 190.3 1 2 0 0.0015 9 0 0 0 8.36E+07 6.15E+07 - - - 2.3335 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.15112.15112.2 0.0507 14-Jun K.FLVGFTNK[136.11].G "sp|P43307|SSRA_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|C9J5W0|C9J5W0_HUMAN" 6 932.5211 1.51 12032 15112 2 932.524011 467.2678 Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3 8.75 3177.6 - 566731 - - - 3.1184 - 1.31 0.29 - 78 1 2 0 0.0029 8 0 0 0 2.10E+08 1.39E+08 - - - 1.9964 0.9906 230117_WJC_METTL3_WT_vs_EV_F02.15113.15113.2 0.515 16-Jul R.LLLPTPTVK[136.11].Q "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 988.6412 2.43 12033 15113 2 988.643241 495.3279 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 3177.8 - 514184 - - - 2.0462 - 1.206 0.138 - 115.6 1 2 0 0.002 9 0 0 0 4.15E+08 1.70E+08 - - - 0.6015 0.9964 230117_WJC_METTL3_WT_vs_EV_F02.15119.15119.2 0.187 12-Jun R.QMSLLLR.R sp|P25705|ATPA_HUMAN 1 859.495 1.5 12037 15119 2 859.49664 430.7548 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 9.75 3178.5 - 643388 - - - 1.957 - 1.384 0.167 - 146.5 1 2 0 0.0017 7 0 0 0 2.31E+08 1.54E+08 - - - 1.3036 0.9862 230117_WJC_METTL3_WT_vs_EV_F02.15124.15124.2 0.664 16-Jun K.MLLYTEVTR[166.11].Y "sp|P31150|GDIA_HUMAN,sp|P50395|GDIB_HUMAN,tr|G5E9U5|G5E9U5_HUMAN,tr|Q5SX86|Q5SX86_HUMAN,tr|Q5SX90|Q5SX90_HUMAN,tr|V9GYF8|V9GYF8_HUMAN,tr|V9GYJ7|V9GYJ7_HUMAN" 7 1134.5983 1.12 12040 15124 2 1134.598769 568.3064 Rab GDP dissociation inhibitor alpha OS=Homo sapiens OX=9606 GN=GDI1 PE=1 SV=2 5.75 3179.1 - 187198 - - - 0.4565 - 1.165 0.12 - 107.1 1 2 0 0.0005 9 0 0 0 2.13E+07 1.90E+07 - - - 0.369 0.9676 230117_WJC_METTL3_WT_vs_EV_F02.15125.15125.2 0.00415 24-Jul K.LFIGGLNTETNEK[136.11].A "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN,tr|H3BNC1|H3BNC1_HUMAN" 7 1442.7497 0.57 12041 15125 2 1442.75715 722.3821 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 4.53 3179.2 - 198625 - - - 5.1922 - 1.387 0.167 - 118.9 1 2 0 0.0075 13 0 0 0 9.22E+05 1.61E+06 - - - 1.1117 0.9554 230117_WJC_METTL3_WT_vs_EV_F02.15138.15138.2 0.0929 18-Aug R.FLSTTIVYPK[136.11].Y sp|Q8N5W9|RFLB_HUMAN 1 1175.6682 1.98 12051 15138 2 1175.6759 588.8414 Refilin-B OS=Homo sapiens OX=9606 GN=RFLNB PE=1 SV=1 8.59 3180.8 - 358498 - - - 6.5818 - 1.395 0.221 - 138.5 1 2 0 0.0077 10 0 0 0 1.18E+07 5.94E+06 - - - 1.6001 0.9911 230117_WJC_METTL3_WT_vs_EV_F02.15141.15141.2 1.45 16-Jul R.VGVAAVGNR[166.11].L "sp|Q6TDP4|KLH17_HUMAN,tr|Q0VGE6|Q0VGE6_HUMAN" 2 851.4853 0.91 12052 15141 2 851.486482 426.7499 Kelch-like protein 17 OS=Homo sapiens OX=9606 GN=KLHL17 PE=1 SV=1 9.72 3181.2 - 1.61E+06 - - - 1.4234 - 1.438 0.091 - 136.7 3 2 0 0.0012 9 0 0 0 4.46E+07 4.89E+07 - - - 0.5505 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.15146.15146.2 1.11 14-Jul K.LLIESLEK.Y "sp|Q8TC07|TBC15_HUMAN,tr|F8VV61|F8VV61_HUMAN,tr|C9JA93|C9JA93_HUMAN" 3 943.559 1.97 12056 15146 2 943.560161 472.7868 TBC1 domain family member 15 OS=Homo sapiens OX=9606 GN=TBC1D15 PE=1 SV=2 4.53 3181.6 - 718757 - - - 1.2315 - 1.571 0.206 - 109.9 1 2 0 0.0012 8 0 0 0 2.52E+07 1.28E+07 - - - 1.9245 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15147.15147.2 0.000525 16-Aug R.AFGYYGPLR[166.11].S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1052.5319 0.99 12057 15147 2 1052.533213 527.2732 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3181.7 - 647173 - - - 1.2608 - 1.719 0.394 - 225.6 1 2 0 0.0013 9 0 0 0 1.24E+09 1.26E+09 - - - 3.518 0.9962 230117_WJC_METTL3_WT_vs_EV_F02.15152.15152.2 0.017 18-Jul K.VLPAVVDIEK.L sp|Q68DQ2|CRBG3_HUMAN 1 1081.6383 3.74 12062 15152 2 1081.642536 541.8264 Very large A-kinase anchor protein OS=Homo sapiens OX=9606 GN=CRYBG3 PE=1 SV=3 4.37 3182.3 - 72551.6 - - - 3.9061 - 1.484 0.282 - 85.1 1 2 0 0.0042 10 0 0 0 3.70E+06 9.89E+05 - - - 2.2244 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15156.15156.2 3.26E-05 16-Oct R.AFGYYGPLR.S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1042.5236 0.99 12064 15156 2 1042.525237 522.2691 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3182.9 - 927578 - - - 1.5549 - 1.8 0.414 - 416.8 1 2 0 0.0016 9 0 0 0 1.24E+09 1.26E+09 - - - 3.7988 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.15160.15160.2 1.90E-05 20-Nov R.VFSGLVSTGLK[136.11].V sp|P13639|EF2_HUMAN 1 1114.6478 4.06 12068 15160 2 1114.650432 558.3312 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.72 3183.4 - 140542 - - - 2.3972 - 1.994 0.478 - 332.7 1 2 0 0.0027 11 0 0 0 1.06E+08 2.60E+07 - - - 4.4377 0.9946 230117_WJC_METTL3_WT_vs_EV_F02.15163.15163.2 0.226 12-Jun R.QMSLLLR[166.11].R sp|P25705|ATPA_HUMAN 1 869.5032 1.56 12069 15163 2 869.50467 435.7589 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 9.75 3183.8 - 3.06E+06 - - - 1.6584 - 1.385 0.117 - 161 1 2 0 0.0014 7 0 0 0 2.31E+08 1.48E+08 - - - 0.9367 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.15164.15164.2 2.37E-06 20-Dec R.VFSGLVSTGLK.V sp|P13639|EF2_HUMAN 1 1106.6336 3.84 12070 15164 2 1106.635457 554.3241 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.72 3183.9 - 1.12E+06 - - - 1.7142 - 2.184 0.407 - 409.5 1 2 0 0.0019 11 0 0 0 9.93E+07 2.59E+07 - - - 4.1597 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.15165.15165.2 0.03 16-Aug K.LVELPYTVK.G sp|Q9NPF4|OSGEP_HUMAN 1 1060.6168 3.43 12071 15165 2 1060.619329 531.3157 Probable tRNA N6-adenosine threonylcarbamoyltransferase OS=Homo sapiens OX=9606 GN=OSGEP PE=1 SV=1 6 3184 - 1.26E+06 - - - 2.3392 - 1.615 0.345 - 181.9 1 2 0 0.0025 9 0 0 0 2.46E+07 7.16E+06 - - - 2.9751 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.15167.15167.2 0.00426 20-Dec R.IALTDNALIAR[166.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1179.6851 0.89 12073 15167 2 1179.686379 590.8498 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3184.3 - 318144 - - - 1.091 - 2.215 0.091 - 404.6 1 2 0 0.0013 11 0 0 0 2.68E+07 3.01E+07 - - - 1.8641 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.15173.15173.2 0.00197 16-Sep K.APGFAQMLK.E sp|P50990|TCPQ_HUMAN 1 961.5055 4.26 12077 15173 2 961.507595 481.76 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.8 3185 - 836923 - - - 2.155 - 1.65 0.327 - 159.4 1 2 0 0.0021 9 0 0 0 1.80E+07 4.23E+06 - - - 2.9043 0.9916 230117_WJC_METTL3_WT_vs_EV_F02.15174.15174.2 2.59 12-Jul K.NLILVVR[166.11].G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 835.5519 1.13 12078 15174 2 835.553305 418.7832 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3185.1 - 4.59E+06 - - - 1.6899 - 1.473 0.047 - 249 1 2 0 0.0014 7 0 0 0 1.69E+08 1.50E+08 - - - 0.6149 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.15175.15175.2 0.00135 20-Sep R.IALTDNALIAR.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1169.6768 0.89 12079 15175 2 1169.679469 585.8457 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3185.2 - 423715 - - - 2.263 - 1.826 0.344 - 177.7 1 2 0 0.0026 11 0 0 0 2.68E+07 3.01E+07 - - - 3.2099 0.9854 230117_WJC_METTL3_WT_vs_EV_F02.15182.15182.2 1.22 12-Jul K.NLILVVR.G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 825.5436 1.13 12084 15182 2 825.544486 413.7791 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3186 - 4.22E+06 - - - 1.0454 - 1.327 0.039 - 172.2 1 2 0 0.0009 7 0 0 0 1.69E+08 1.50E+08 - - - 0.2252 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.15183.15183.2 0.0126 14-Jul K.NVPYVFVR.S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 992.5444 1.16 12085 15183 2 992.546548 497.2795 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3186.1 - 1.45E+06 - - - 2.2135 - 1.167 0.367 - 200.8 1 2 0 0.0022 8 0 0 0 3.22E+08 2.78E+08 - - - 2.2167 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15187.15187.2 0.00419 14-Aug K.AFAMIIDK.L "sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BND9|H3BND9_HUMAN" 8 907.4837 2.57 12088 15187 2 907.485346 454.7491 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 5.88 3186.6 - 1.79E+06 - - - 1.7863 - 1.598 0.421 - 211.4 1 2 0 0.0016 8 0 0 0 7.92E+07 3.08E+07 - - - 3.5637 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.15189.15189.2 0.154 16-Oct R.LLGYVATLK[136.11].D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 984.6099 2.37 12089 15189 2 984.611213 493.3122 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 8.59 3186.8 - 3.51E+06 - - - 1.3152 - 1.964 0.319 - 221.3 1 2 0 0.0013 9 0 0 0 3.56E+08 1.50E+08 - - - 3.3495 1 230117_WJC_METTL3_WT_vs_EV_F02.15206.15206.2 2.11E-05 16-Oct K.YMAC[160.03]C[160.03]LLYR.G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1248.5454 3 12100 15206 2 1248.544257 625.28 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3188.7 - 795826 - - - -0.8802 - 1.939 0.615 - 417.5 1 2 0 -0.0011 9 0 0 0 2.11E+08 7.02E+07 - - - 5.4987 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.15209.15209.2 0.0191 12-Jun K.EILFYDR.L sp|Q08J23|NSUN2_HUMAN 1 954.4811 1.9 12103 15209 2 954.481405 478.2478 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.37 3189 - 1.48E+06 - - - 0.3384 - 1.454 0.345 - 165.6 1 2 0 0.0003 7 0 0 0 1.08E+08 5.66E+07 - - - 2.7751 1 230117_WJC_METTL3_WT_vs_EV_F02.15212.15212.2 5.81E-05 16-Sep K.YMAC[160.03]C[160.03]LLYR[166.11].G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1258.5536 3 12104 15212 2 1258.551815 630.2841 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3189.4 - 451076 - - - -1.439 - 1.737 0.59 - 281.2 1 2 0 -0.0018 9 0 0 0 2.11E+08 7.02E+07 - - - 4.9956 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.15224.15224.2 0.0244 22-Jul K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.27 12110 15224 2 1287.757667 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3191 - 336031 - - - -0.1522 - 1.624 0.222 - 94.1 1 2 0 -0.0002 12 0 0 0 2.42E+07 1.91E+07 - - - 1.9565 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.15235.15235.2 0.0239 12-Aug R.FLTVMMK[136.11].H "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 876.4693 1.22 12116 15235 2 876.469869 439.2419 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.75 3192.3 - 4.47E+06 - - - 0.6868 - 1.45 0.324 - 198.4 1 2 0 0.0006 7 0 0 0 2.25E+08 1.85E+08 - - - 2.6112 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.15236.15236.2 0.113 18-Jun R.LVVLGIRPIR.L sp|Q92900|RENT1_HUMAN 1 1134.7601 1.07 12117 15236 2 1134.759096 568.3873 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 12 3192.4 - 341385 - - - -0.883 - 1.25 0.429 - 50.8 1 2 0 -0.001 10 0 0 0 8.94E+06 8.33E+06 - - - 2.8321 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.15237.15237.2 0.096 12-Aug R.FLTVMMK.H "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 868.4551 1.25 12118 15237 2 868.454545 435.2348 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.75 3192.5 - 3.42E+06 - - - -0.6011 - 1.453 0.205 - 208.8 1 2 0 -0.0005 7 0 0 0 2.24E+08 1.80E+08 - - - 1.7388 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.15245.15245.2 0.0427 16-Aug R.LPEAAFLAR.T "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 986.5549 2.6 12123 15245 2 986.555173 494.2847 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 6 3193.4 - 2.36E+06 - - - 0.2605 - 1.456 0.168 - 174.7 1 2 0 0.0003 9 0 0 0 1.93E+08 7.43E+07 - - - 1.3687 0.9751 230117_WJC_METTL3_WT_vs_EV_F02.15255.15255.2 0.35 12-Jun R.LYIWSGR[166.11].D "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 903.4842 2.25 12131 15255 2 903.482473 452.7494 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 8.75 3194.5 - 730767 - - - -1.9203 - 1.248 0.163 - 121.3 1 2 0 -0.0017 7 0 0 0 7.43E+07 3.31E+07 - - - 0.9463 0.999 230117_WJC_METTL3_WT_vs_EV_F02.15259.15259.2 0.00988 14-Aug K.LIINSLYK.N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 962.5801 0.96 12132 15259 2 962.581025 482.2973 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3195.1 - 1.25E+07 - - - 0.9942 - 1.354 0.326 - 126.2 1 2 0 0.001 8 0 0 0 1.58E+08 1.64E+08 - - - 2.3626 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.15261.15261.2 4.54 12-Sep K.YAWVLDK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 14 893.4647 2.33 12133 15261 2 893.465242 447.7396 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 3195.4 - 2.34E+06 - - - 0.6022 - 1.557 0.158 - 264.1 1 2 0 0.0005 7 0 0 0 9.13E+07 3.91E+07 - - - 1.6107 0.9129 230117_WJC_METTL3_WT_vs_EV_F02.15262.15262.2 0.404 12-Apr K.LVFDGLR[166.11].K sp|P15924|DESP_HUMAN 1 828.4733 37.84 12134 15262 2 828.471843 415.2439 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.84 3195.5 - 1.25E+06 - - - -1.7683 - 1.054 0.132 - 56.7 3 2 0 -0.0015 7 0 0 0 1.49E+09 3.94E+07 - - - -0.031 0.9645 230117_WJC_METTL3_WT_vs_EV_F02.15277.15277.2 2.96 14-Jul K.GLVFLNGK.L sp|L0R8F8|MIDUO_HUMAN 1 846.4963 1.73 12143 15277 2 846.497791 424.2554 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 8.75 3197.2 - 3.15E+06 - - - 1.7153 - 1.108 0.04 - 175.2 1 2 0 0.0015 8 0 0 0 6.79E+07 3.92E+07 - - - -0.3547 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.15283.15283.2 0.633 14-Jul K.LIINSLYK[136.11].N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 970.5943 0.96 12147 15283 2 970.594038 486.3044 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3197.8 - 4.32E+06 - - - -0.237 - 1.206 0.262 - 92 1 2 0 -0.0002 8 0 0 0 1.58E+08 1.64E+08 - - - 1.541 0.9839 230117_WJC_METTL3_WT_vs_EV_F02.15285.15285.2 0.275 14-Jul R.VLNLEALK.Q "sp|Q6NSW5|DE10B_HUMAN,sp|Q8TCE6|DEN10_HUMAN,tr|A0A3B3IRE4|A0A3B3IRE4_HUMAN" 3 898.5488 3.56 12149 15285 2 898.550119 450.2817 Putative DENN domain-containing protein 10 B OS=Homo sapiens OX=9606 GN=DENND10P1 PE=5 SV=1 5.97 3198.1 - 772552 - - - 1.5035 - 1.396 0.014 - 91 1 2 0 0.0014 8 0 0 0 1.37E+07 3.84E+06 - - - 0.1501 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.15290.15290.2 0.00138 18-Oct R.LVQAFQFTDK.H "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 3 1195.6237 2.46 12151 15290 2 1195.622274 598.8191 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.84 3198.8 - 313890 - - - -1.2128 - 1.633 0.352 - 207.5 1 2 0 -0.0014 10 0 0 0 5.80E+06 2.36E+06 - - - 3.0093 0.9938 230117_WJC_METTL3_WT_vs_EV_F02.15292.15292.2 0.695 18-Jul K.IVLLSANSIR.A "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 1084.6604 1.97 12152 15292 2 1084.660426 543.3375 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 9.75 3199 - 2.95E+06 - - - -0.0166 - 1.352 0.166 - 135.5 1 2 0 0 10 0 0 0 3.23E+07 1.64E+07 - - - 1.1089 0.9945 230117_WJC_METTL3_WT_vs_EV_F02.15297.15297.2 0.0446 22-Sep K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.26 12155 15297 2 1277.748198 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3199.6 - 345098 - - - -1.0918 - 1.589 0.202 - 125.8 1 2 0 -0.0014 12 0 0 0 2.48E+07 1.97E+07 - - - 1.751 0.9816 230117_WJC_METTL3_WT_vs_EV_F02.15306.15306.2 1.31 16-Jun R.YLYLSTMER.S "sp|Q10570|CPSF1_HUMAN,tr|A0A087X101|A0A087X101_HUMAN" 2 1174.5692 0.92 12162 15306 2 1174.572012 588.2919 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6 3200.8 - 271148 - - - 2.3549 - 1.136 0.11 - 116 1 2 0 0.0028 9 0 0 0 3.79E+06 4.13E+06 - - - 0.2215 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15310.15310.2 4.13E-05 22-Dec K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 298.65 12164 15310 2 1356.688155 679.3515 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3201.3 - 615008 - - - -0.2609 - 2.666 0.385 - 564.1 1 2 0 -0.0004 12 0 0 0 1.60E+07 5.37E+04 - - - 4.4646 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.15317.15317.2 0.0336 14-Jul R.FADFTVYR[166.11].N "sp|Q9NY61|AATF_HUMAN,tr|A0A7P0T868|A0A7P0T868_HUMAN,tr|A0A7P0TAR0|A0A7P0TAR0_HUMAN,tr|A0A7P0TBI0|A0A7P0TBI0_HUMAN,tr|A0A7P0Z4P2|A0A7P0Z4P2_HUMAN,tr|A0A7P0Z4N2|A0A7P0Z4N2_HUMAN,tr|A0A087WTH8|A0A087WTH8_HUMAN,tr|A0A7P0Z434|A0A7P0Z434_HUMAN" 8 1027.5003 1.01 12169 15317 2 1027.503442 514.7574 Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1 5.84 3202.1 - 1.50E+06 - - - 3.1046 - 1.504 0.411 - 138.5 1 2 0 0.0032 8 0 0 0 1.91E+07 1.89E+07 - - - 3.3065 0.9969 230117_WJC_METTL3_WT_vs_EV_F02.15318.15318.2 0.992 12-Aug R.IYLYLTK.V "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 912.5321 1.8 12170 15318 2 912.532763 457.2733 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.5 3202.2 - 1.35E+06 - - - 0.7759 - 1.696 0.095 - 234.8 1 2 0 0.0007 7 0 0 0 6.09E+07 3.38E+07 - - - 1.4163 0.9939 230117_WJC_METTL3_WT_vs_EV_F02.15319.15319.2 0.797 12-Aug R.IYLYLTK[136.11].V "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 920.5463 1.83 12171 15319 2 920.547143 461.2804 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.5 3202.3 - 980959 - - - 0.9646 - 1.492 0.073 - 218.3 1 2 0 0.0009 7 0 0 0 6.08E+07 3.33E+07 - - - 0.8477 0.9951 230117_WJC_METTL3_WT_vs_EV_F02.15322.15322.2 0.085 16-Aug R.YLYLSTMER[166.11].S "sp|Q10570|CPSF1_HUMAN,tr|A0A087X101|A0A087X101_HUMAN" 2 1184.5775 0.92 12174 15322 2 1184.575525 593.296 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6 3202.7 - 294938 - - - -1.6808 - 1.485 0.275 - 224.2 1 2 0 -0.002 9 0 0 0 3.79E+06 4.13E+06 - - - 2.2155 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.15336.15336.2 0.897 12-Jul K.FLLLQQK[136.11].Y "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 896.5575 2.04 12184 15336 2 896.559189 449.286 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 8.75 3204.5 - 576060 - - - 1.8961 - 1.311 0.217 - 120.1 1 2 0 0.0017 7 0 0 0 5.56E+07 2.72E+07 - - - 1.5012 0.8809 230117_WJC_METTL3_WT_vs_EV_F02.15337.15337.2 0.184 16-Jun K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 44.75 12185 15337 2 1014.54153 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3204.5 - 4.53E+06 - - - 6.8554 - 1.396 0.138 - 70.1 2 2 0 0.007 9 0 0 0 2.04E+08 4.55E+06 - - - 0.8888 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.15338.15338.2 0.0367 14-Jul R.LLLNYAVR.L "sp|Q92989|CLP1_HUMAN,tr|E9PL17|E9PL17_HUMAN,tr|E9PKV5|E9PKV5_HUMAN" 3 960.5757 1.44 12186 15338 2 960.577762 481.2951 Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1 8.75 3204.6 - 701567 - - - 2.1966 - 1.45 0.262 - 144.9 1 2 0 0.0021 8 0 0 0 1.39E+08 9.70E+07 - - - 2.0961 0.9722 230117_WJC_METTL3_WT_vs_EV_F02.15343.15343.2 0.000679 13/16 R.PAVLSGYFK.Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 980.5331 1.06 12189 15343 2 980.53548 491.2738 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.01 3205.4 - 1.44E+06 - - - 2.4089 - 2.201 0.41 - 656 1 1 0 0.0024 9 0 0 0 1.50E+08 1.41E+08 - - - 4.3509 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.15344.15344.2 0.0115 18-Aug K.LVIIEGDLER[166.11].T "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1165.6582 1.22 12190 15344 2 1165.657749 583.8364 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.14 3205.6 - 566075 - - - -0.3946 - 1.854 0.347 - 203.6 1 2 0 -0.0005 10 0 0 0 2.20E+07 1.80E+07 - - - 3.327 0.996 230117_WJC_METTL3_WT_vs_EV_F02.15345.15345.2 0.0799 12-Jul K.SEFVILR[166.11].D "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 872.4995 1 12191 15345 2 872.502429 437.257 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 5.72 3205.7 - 514606 - - - 3.3307 - 1.656 0.16 - 250.1 1 2 0 0.0029 7 0 0 0 5.76E+07 5.74E+07 - - - 1.8201 0.9963 230117_WJC_METTL3_WT_vs_EV_F02.15346.15346.2 0.00103 14-Aug R.NIVLYDMR.Q "sp|Q9NV06|DCA13_HUMAN,tr|A0A087WT20|A0A087WT20_HUMAN,tr|A0A087X1F8|A0A087X1F8_HUMAN" 3 1022.5219 999 12192 15346 2 1022.526687 512.2682 DDB1- and CUL4-associated factor 13 OS=Homo sapiens OX=9606 GN=DCAF13 PE=1 SV=2 5.84 3205.8 - 449939 - - - 4.6806 - 1.355 0.391 - 202.5 1 2 0 0.0048 8 0 0 0 7.67E+06 0.00E+00 - - - 2.8437 1 230117_WJC_METTL3_WT_vs_EV_F02.15349.15349.2 4.26E-06 18-Sep R.LITLEEEMTK.Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1205.6213 3.68 12195 15349 2 1205.626714 603.8179 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3206.2 - 227470 - - - 4.4566 - 2.016 0.545 - 201.6 1 2 0 0.0054 10 0 0 0 2.87E+07 7.80E+06 - - - 5.0217 0.9907 230117_WJC_METTL3_WT_vs_EV_F02.15354.15354.2 0.159 12-Jun R.QPVILWK.E sp|Q9UKN8|TF3C4_HUMAN 1 882.5327 0.84 12199 15354 2 882.535607 442.2736 General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2 8.75 3206.8 - 468867 - - - 3.2667 - 1.161 0.213 - 123 1 2 0 0.0029 7 0 0 0 1.13E+07 1.34E+07 - - - 1.0863 0.9937 230117_WJC_METTL3_WT_vs_EV_F02.15356.15356.2 0.0599 14-Aug K.LGFESIYK.L "sp|P49643|PRI2_HUMAN,tr|A0A5F9ZHU7|A0A5F9ZHU7_HUMAN" 2 955.5015 1.98 12200 15356 2 955.504778 478.758 DNA primase large subunit OS=Homo sapiens OX=9606 GN=PRIM2 PE=1 SV=2 6 3207.1 - 1.12E+06 - - - 3.4474 - 1.412 0.191 - 128.8 1 2 0 0.0033 8 0 0 0 1.68E+07 8.46E+06 - - - 1.4912 0.9668 230117_WJC_METTL3_WT_vs_EV_F02.15358.15358.2 3.95 14-Jun R.LFIGGIPK.M "sp|A0AV96|RBM47_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6REZ6|D6REZ6_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 5 843.5218 1.24 12202 15358 2 843.526281 422.7682 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 8.75 3207.3 - 1.42E+06 - - - 5.2826 - 1.353 0.161 - 102.1 1 2 0 0.0045 8 0 0 0 4.81E+07 3.87E+07 - - - 1.1405 0.9952 230117_WJC_METTL3_WT_vs_EV_F02.15361.15361.2 0.0739 12-Jun R.WFVTC[160.03]VR.Q "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN,tr|A0A140T954|A0A140T954_HUMAN" 3 966.4746 0.81 12205 15361 2 966.478123 484.2446 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 8.25 3207.6 - 308460 - - - 3.6887 - 1.17 0.316 - 97.4 1 2 0 0.0036 7 0 0 0 8.33E+06 1.03E+07 - - - 1.8713 0.9591 230117_WJC_METTL3_WT_vs_EV_F02.15368.15368.2 0.0809 12-Jun R.WGGLDLR.R sp|Q9H7N4|SFR19_HUMAN 1 815.429 0.92 12210 15368 2 815.431274 408.7218 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.84 3208.5 - 2.09E+06 - - - 2.8047 - 1.136 0.054 - 175.3 1 2 0 0.0023 7 0 0 0 4.95E+07 5.40E+07 - - - -0.1568 0.9943 230117_WJC_METTL3_WT_vs_EV_F02.15371.15371.2 0.172 12-Jul R.LIMQYLK[136.11].E sp|Q2TAY7|SMU1_HUMAN 1 915.5343 0.92 12213 15371 2 915.535971 458.7744 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.59 3208.7 - 1.74E+06 - - - 1.8131 - 1.264 0.154 - 135.5 1 2 0 0.0017 7 0 0 0 6.02E+07 6.52E+07 - - - 0.9203 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.15372.15372.2 0.000327 18-Sep R.LITLEEEMTK[136.11].Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1213.6355 4.39 12214 15372 2 1213.637946 607.825 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3208.8 - 339317 - - - 1.9816 - 1.78 0.505 - 206.2 1 2 0 0.0024 10 0 0 0 2.78E+07 6.34E+06 - - - 4.3797 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.15374.15374.2 0.000169 20-Aug R.LVEMASSLAIR.E "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1188.6536 4.52 12216 15374 2 1188.658944 595.3341 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3209.1 - 167366 - - - 4.4588 - 1.763 0.447 - 145.1 1 2 0 0.0053 11 0 0 0 7.06E+06 1.56E+06 - - - 3.8748 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.15376.15376.2 0.146 12-Jul K.SEFVILR.D "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 862.4913 1 12217 15376 2 862.492296 432.2529 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 5.72 3209.3 - 2.45E+06 - - - 1.2093 - 1.638 0.162 - 329.1 1 2 0 0.001 7 0 0 0 5.76E+07 5.74E+07 - - - 1.8008 0.9211 230117_WJC_METTL3_WT_vs_EV_F02.15390.15390.2 0.00465 16-Sep R.AVFPSIVGR[166.11].P "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 31 954.5526 1.24 12228 15390 2 954.555974 478.2836 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 9.79 3211 - 1.39E+06 - - - 3.5126 - 1.817 0.365 - 249.2 1 1 0 0.0034 9 0 0 0 1.06E+09 8.50E+08 - - - 3.4635 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.15392.15392.2 0.0786 18-Sep K.SYLYPSTLVR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1197.6394 0.36 12230 15392 2 1197.640442 599.827 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 3211.2 - 736665 - - - 0.8918 - 1.879 0.318 - 324.6 1 2 0 0.0011 10 0 0 0 4.31E+08 1.19E+09 - - - 3.15 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.15397.15397.2 0.0159 16-Nov K.LGEWVGLC[160.03]K[136.11].L sp|P25398|RS12_HUMAN 1 1068.5518 2.24 12233 15397 2 1068.553081 535.2832 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3211.8 - 3.96E+06 - - - 1.2437 - 2.163 0.396 - 433.3 1 2 0 0.0013 9 0 0 0 3.52E+08 1.57E+08 - - - 4.1974 0.9319 230117_WJC_METTL3_WT_vs_EV_F02.15398.15398.2 0.00588 16-Aug R.AVFPSIVGR.P "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 31 944.5444 1.23 12234 15398 2 944.54593 473.2795 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 9.79 3211.9 - 2.58E+06 - - - 1.6717 - 1.566 0.293 - 247.1 1 1 0 0.0016 9 0 0 0 1.05E+09 8.49E+08 - - - 2.5022 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.15402.15402.2 0.0593 18-Jul K.VLFTGVVDAR[166.11].G sp|Q14676|MDC1_HUMAN 1 1085.6109 2.56 12237 15402 2 1085.610999 543.8127 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 5.81 3212.4 - 551969 - - - 0.1234 - 1.462 0.276 - 128.6 1 2 0 0.0001 10 0 0 0 4.42E+07 1.73E+07 - - - 2.1396 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15416.15416.2 0.000437 14-Aug R.GFTLVGMK[136.11].M "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 859.4717 0.95 12245 15416 2 859.472986 430.7431 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.75 3214 - 3.72E+06 - - - 1.4846 - 1.676 0.41 - 259.6 1 2 0 0.0013 8 0 0 0 8.85E+08 9.28E+08 - - - 3.6263 1 230117_WJC_METTL3_WT_vs_EV_F02.15425.15425.2 0.275 13/22 K.AVASAAAALVLK.A sp|Q9Y490|TLN1_HUMAN 1 1083.6652 1.14 12250 15425 2 1083.666978 542.8399 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.8 3215.1 - 766282 - - - 1.6453 - 2.668 0.44 - 402.1 1 2 0 0.0018 12 0 0 0 3.01E+07 2.63E+07 - - - 4.8723 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.15429.15429.2 0.466 12-Aug K.TSILVFK[136.11].D sp|Q9BRS2|RIOK1_HUMAN 1 814.5044 0.62 12252 15429 2 814.506519 408.2595 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 8.41 3215.6 - 1.75E+06 - - - 2.6126 - 1.89 0.326 - 301.9 1 2 0 0.0021 7 0 0 0 4.09E+07 6.64E+07 - - - 3.4652 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.15437.15437.2 0.000276 14-Aug K.NVPYVFVR.S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 992.5444 0.83 12257 15437 2 992.545332 497.2795 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3216.6 - 1.75E+06 - - - 0.9884 - 1.405 0.453 - 260.7 1 2 0 0.001 8 0 0 0 1.16E+08 1.40E+08 - - - 3.4121 0.8528 230117_WJC_METTL3_WT_vs_EV_F02.15445.15445.2 0.114 18-Aug K.LLHHLSDLAL.T "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1130.6448 - 12260 15445 2 1130.646548 566.3297 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3217.6 - 1.06E+06 - - - 1.5513 - 1.577 0.182 - 155.6 1 1 0 0.0018 10 0 0 0 - - - - - 1.6562 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.15447.15447.2 0.0437 18-Jul K.VLFTGVVDAR.G sp|Q14676|MDC1_HUMAN 1 1075.6026 2.65 12261 15447 2 1075.603062 538.8086 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 5.81 3217.8 - 684422 - - - 0.4342 - 1.658 0.192 - 133 2 2 0 0.0005 10 0 0 0 4.83E+07 1.82E+07 - - - 1.7358 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.15449.15449.2 6.39E-05 16-Nov K.LGEWVGLC[160.03]K.L sp|P25398|RS12_HUMAN 1 1060.5376 2.24 12262 15449 2 1060.538627 531.2761 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3218.1 - 5.10E+06 - - - 1.0136 - 2.207 0.438 - 452.6 1 2 0 0.0011 9 0 0 0 3.52E+08 1.57E+08 - - - 4.566 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.15450.15450.2 0.0524 12-Aug K.LC[160.03]TFILK[136.11].N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 901.5187 1.2 12263 15450 2 901.519262 451.7666 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3218.1 - 484521 - - - 0.6667 - 1.461 0.169 - 134.4 1 2 0 0.0006 7 0 0 0 3.43E+07 2.87E+07 - - - 1.4903 0.9827 230117_WJC_METTL3_WT_vs_EV_F02.15452.15452.2 14 14-Aug K.AGLSVLLK.A "sp|Q969N2|PIGT_HUMAN,tr|A0A1W2PRZ8|A0A1W2PRZ8_HUMAN,tr|H7C2Y2|H7C2Y2_HUMAN,tr|A0A1W2PPR6|A0A1W2PPR6_HUMAN,tr|A0A1W2PPS0|A0A1W2PPS0_HUMAN,tr|A0A1W2PR92|A0A1W2PR92_HUMAN,tr|A0A1W2PPI8|A0A1W2PPI8_HUMAN,tr|A0A1W2PRG1|A0A1W2PRG1_HUMAN,tr|A0A1W2PRV7|A0A1W2PRV7_HUMAN,tr|A0A1W2PQ52|A0A1W2PQ52_HUMAN,tr|A0A1W2PRH2|A0A1W2PRH2_HUMAN,tr|A0A1W2PNP0|A0A1W2PNP0_HUMAN,tr|A0A1W2PNW9|A0A1W2PNW9_HUMAN,tr|A0A1W2PP57|A0A1W2PP57_HUMAN,tr|A0A1W2PPQ7|A0A1W2PPQ7_HUMAN,tr|A0A1W2PQ29|A0A1W2PQ29_HUMAN,tr|A0A1W2PQN1|A0A1W2PQN1_HUMAN,tr|A0A1W2PPC3|A0A1W2PPC3_HUMAN" 18 799.5167 1.22 12265 15452 2 799.518064 400.7656 GPI transamidase component PIG-T OS=Homo sapiens OX=9606 GN=PIGT PE=1 SV=1 8.8 3218.3 - 627069 - - - 1.656 - 1.096 0.108 - 111.1 1 2 0 0.0013 8 0 0 0 2.68E+07 2.18E+07 - - - 0.1147 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.15453.15453.2 7.92E-05 22-Dec R.EHALLAYTLGVK.Q "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 11 1313.7343 6.33 12266 15453 2 1313.739099 657.8744 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.85 3218.4 - 476608 - - - 3.6248 - 2.136 0.407 - 223.5 1 2 0 0.0048 12 0 0 0 6.03E+06 9.51E+05 - - - 4.0425 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.15454.15454.2 0.691 14-Aug K.ILEDSFLK.S sp|Q9Y6X8|ZHX2_HUMAN 1 963.5277 6.42 12267 15454 2 963.529609 482.7711 Zinc fingers and homeoboxes protein 2 OS=Homo sapiens OX=9606 GN=ZHX2 PE=1 SV=1 4.37 3218.6 - 403179 - - - 1.9833 - 1.349 0.23 - 135 1 2 0 0.0019 8 0 0 0 2.27E+07 3.54E+06 - - - 1.642 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.15455.15455.2 0.013 22-Jun R.EHALLAYTLGVK[136.11].Q "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 11 1321.7485 5.68 12268 15455 2 1321.754001 661.8815 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.85 3218.7 - 174162 - - - 4.1339 - 1.581 0.371 - 100 1 2 0 0.0055 12 0 0 0 5.88E+06 1.03E+06 - - - 2.9847 0.9957 230117_WJC_METTL3_WT_vs_EV_F02.15460.15460.2 0.21 12-Jun K.LC[160.03]TFILK.N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 893.5045 1.21 12271 15460 2 893.505505 447.7595 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3219.3 - 951911 - - - 1.1684 - 1.171 0.211 - 82.6 1 2 0 0.001 7 0 0 0 3.61E+07 2.98E+07 - - - 1.0993 0.998 230117_WJC_METTL3_WT_vs_EV_F02.15476.15476.2 0.0626 22-Oct K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.19 12280 15476 2 1287.759013 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3221.2 - 663361 - - - 0.893 - 1.523 0.219 - 169.1 1 2 0 0.0011 12 0 0 0 6.83E+07 5.76E+07 - - - 1.7651 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.15478.15478.2 0.233 12-Jul R.FLVTVIK.D "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 818.5266 1.54 12281 15478 2 818.527866 410.2706 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3221.5 - 1.93E+06 - - - 1.576 - 1.392 0.141 - 170.9 1 2 0 0.0013 7 0 0 0 1.03E+08 6.71E+07 - - - 1.13 0.9324 230117_WJC_METTL3_WT_vs_EV_F02.15482.15482.2 3.63 14-May K.VGRPTASK.A sp|Q9H1E3|NUCKS_HUMAN 1 814.4661 0.13 12284 15482 2 814.467605 408.2403 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 OS=Homo sapiens OX=9606 GN=NUCKS1 PE=1 SV=1 11 3221.9 - 1.80E+06 - - - 1.8466 - 1.115 0.041 - 80.6 9 2 0 0.0015 8 0 0 0 2.65E+08 2.07E+09 - - - -0.7546 0.908 230117_WJC_METTL3_WT_vs_EV_F02.15483.15483.2 1.22 14-Jul K.NVPYVFVR[166.11].S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 1002.5526 0.36 12285 15483 2 1002.558433 502.2836 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3221.9 - 1.69E+06 - - - 5.7972 - 1.157 0.152 - 81.3 1 2 0 0.0058 8 0 0 0 3.16E+07 8.86E+07 - - - 0.6017 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.15506.15506.2 0.0556 16-Aug R.LIVNVNDLR[166.11].R sp|P25205|MCM3_HUMAN 1 1064.6218 5.75 12298 15506 2 1064.62344 533.3182 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.84 3224.8 - 1.41E+06 - - - 1.5743 - 1.568 0.25 - 195.3 1 2 0 0.0017 9 0 0 0 1.35E+08 2.35E+07 - - - 2.1883 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.15507.15507.2 0.000345 16-Oct R.AATLMMLGR.F "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PR93|A0A6I8PR93_HUMAN,tr|K7ESP1|K7ESP1_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|K7EJE9|K7EJE9_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|K7ELJ8|K7ELJ8_HUMAN,tr|K7EN19|K7EN19_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EJL5|K7EJL5_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|K7EJV7|K7EJV7_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 21 962.5041 0.99 12299 15507 2 962.504979 482.2593 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 9.79 3224.9 - 1.08E+06 - - - 0.8686 - 1.732 0.35 - 267.5 1 2 0 0.0008 9 0 0 0 4.89E+07 4.96E+07 - - - 3.2149 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.15513.15513.2 0.0809 14-Jul R.LLEC[160.03]YFTR[166.11].S "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1110.5407 2.23 12303 15513 2 1110.542612 556.2776 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.99 3225.8 - 374590 - - - 1.6893 - 1.44 0.258 - 117.1 1 2 0 0.0019 8 0 0 0 2.34E+07 1.05E+07 - - - 2.0457 0.9803 230117_WJC_METTL3_WT_vs_EV_F02.15516.15516.2 4.03 12-Jun K.DFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 834.46 1.82 12304 15516 2 834.461166 418.2373 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.84 3226.2 - 4.89E+07 - - - 1.4536 - 1.146 0.073 - 122.4 1 2 0 0.0012 7 0 0 0 1.20E+09 6.58E+08 - - - 0.0116 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.15518.15518.2 0.017 14-Jul R.LYNYFYDR.R "sp|Q96GD4|AURKB_HUMAN,tr|J3QR41|J3QR41_HUMAN,tr|J3QLN8|J3QLN8_HUMAN,tr|J3KTD6|J3KTD6_HUMAN,tr|J3KT86|J3KT86_HUMAN" 5 1152.524 2.56 12306 15518 2 1152.526222 577.2693 Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3 5.83 3226.4 - 471950 - - - 1.9193 - 1.302 0.296 - 138.6 1 2 0 0.0022 8 0 0 0 7.32E+06 2.86E+06 - - - 2.0225 0.9845 230117_WJC_METTL3_WT_vs_EV_F02.15523.15523.2 0.141 12-Aug R.C[160.03]ILPFDK.E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 891.4524 1.26 12308 15523 2 891.451674 446.7335 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.83 3227 - 1.58E+06 - - - -0.8424 - 1.442 0.08 - 317.2 1 2 0 -0.0008 7 0 0 0 1.32E+08 1.04E+08 - - - 0.7914 0.9849 230117_WJC_METTL3_WT_vs_EV_F02.15526.15526.2 0.0432 12-Jul K.YIQELWR[166.11].K "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1016.5319 0.77 12311 15526 2 1016.527156 509.2732 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 6 3227.2 - 1.88E+06 - - - -4.6531 - 1.553 0.355 - 194 1 2 0 -0.0047 7 0 0 0 1.03E+08 1.34E+08 - - - 3.0563 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.15528.15528.2 4.63E-06 20-Aug K.WEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1215.6288 0.82 12313 15528 2 1215.629726 608.8217 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3227.4 - 362181 - - - 0.7543 - 1.832 0.491 - 127.8 1 2 0 0.0009 11 0 0 0 3.79E+07 4.62E+07 - - - 4.305 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.15534.15534.2 0.485 14-Aug R.GLVVPVIR[166.11].N sp|P36957|ODO2_HUMAN 1 861.5675 0.87 12317 15534 2 861.567549 431.791 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3228.2 - 7.08E+06 - - - 0.007 - 1.738 0.241 - 374.8 1 2 0 0 8 0 0 0 8.07E+07 9.31E+07 - - - 2.488 0.9888 230117_WJC_METTL3_WT_vs_EV_F02.15535.15535.2 5.73 12-Jul R.LWISVAR[166.11].Y sp|Q15029|U5S1_HUMAN 1 853.5049 1.56 12318 15535 2 853.504738 427.7597 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 9.75 3228.2 - 6.71E+06 - - - -0.2402 - 1.359 0.101 - 244.1 1 2 0 -0.0002 7 0 0 0 1.60E+08 1.03E+08 - - - 0.7589 0.9774 230117_WJC_METTL3_WT_vs_EV_F02.15541.15541.2 0.0865 14-Jun K.VFPLAEYR.T sp|Q86T24|KAISO_HUMAN 1 993.5284 5.04 12322 15541 2 993.526154 497.7715 Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2 5.97 3228.9 - 290548 - - - -2.2274 - 1.266 0.192 - 129.6 1 2 0 -0.0022 8 0 0 0 1.84E+07 3.66E+06 - - - 1.1698 0.9585 230117_WJC_METTL3_WT_vs_EV_F02.15544.15544.2 2.07 16-May K.FVPLLPGNR.S sp|P78527|PRKDC_HUMAN 1 1011.5866 1.04 12323 15544 2 1011.587012 506.8006 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3229.3 - 582048 - - - 0.4557 - 1.051 0.079 - 75 2 2 0 0.0005 9 0 0 0 4.51E+07 4.31E+07 - - - -0.3662 0.9916 230117_WJC_METTL3_WT_vs_EV_F02.15546.15546.2 2.25 14-Jun R.GLVVPVIR.N sp|P36957|ODO2_HUMAN 1 851.5593 0.87 12325 15546 2 851.559284 426.7869 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3229.4 - 2.52E+06 - - - 0.0129 - 1.391 0.113 - 180.6 1 2 0 0 8 0 0 0 8.07E+07 9.31E+07 - - - 0.8709 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.15551.15551.2 0.0128 22-Oct K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.21 12328 15551 2 1277.750912 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3230.1 - 758630 - - - 1.0323 - 1.627 0.358 - 210.6 1 2 0 0.0013 12 0 0 0 3.38E+07 2.80E+07 - - - 2.9655 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15552.15552.2 0.0513 18-Oct K.ALVLTEIGPK.R sp|O14732|IMPA2_HUMAN 1 1039.6277 49.9 12329 15552 2 1039.629529 520.8211 Inositol monophosphatase 2 OS=Homo sapiens OX=9606 GN=IMPA2 PE=1 SV=1 6.05 3230.2 - 360972 - - - 1.7141 - 1.93 0.392 - 308.2 1 2 0 0.0018 10 0 0 0 8.51E+06 1.71E+05 - - - 3.7711 0.9884 230117_WJC_METTL3_WT_vs_EV_F02.15553.15553.2 0.556 16-Jun K.FVPLLPGNR[166.11].S sp|P78527|PRKDC_HUMAN 1 1021.5948 1.04 12330 15553 2 1021.595889 511.8047 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3230.3 - 1.23E+06 - - - 1.0454 - 1.238 0.098 - 125.3 1 2 0 0.0011 9 0 0 0 4.51E+07 4.32E+07 - - - 0.3822 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.15554.15554.2 0.132 14-Jul K.FLILNPSK.R "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 930.5539 0.34 12331 15554 2 930.554589 466.2842 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 8.75 3230.5 - 778270 - - - 0.7899 - 1.279 0.335 - 110.5 1 2 0 0.0007 8 0 0 0 1.59E+07 4.62E+07 - - - 2.2572 0.9949 230117_WJC_METTL3_WT_vs_EV_F02.15555.15555.2 0.0219 16-Jul K.LITWSPVC[160.03]R.N "sp|P07203|GPX1_HUMAN,tr|A0A2R8Y6B6|A0A2R8Y6B6_HUMAN" 2 1130.5907 1.76 12332 15555 2 1130.596192 566.3026 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 8.25 3230.6 - 412683 - - - 4.9019 - 1.611 0.303 - 168.8 1 2 0 0.0055 9 0 0 0 8.91E+06 5.07E+06 - - - 2.6568 0.9965 230117_WJC_METTL3_WT_vs_EV_F02.15556.15556.2 0.0707 20-Sep R.FIDTTLAITSR.F "sp|Q9Y5J9|TIM8B_HUMAN,tr|G3XAN8|G3XAN8_HUMAN" 2 1236.6714 1.72 12333 15556 2 1236.669992 619.343 Mitochondrial import inner membrane translocase subunit Tim8 B OS=Homo sapiens OX=9606 GN=TIMM8B PE=1 SV=1 5.84 3230.7 - 249303 - - - -1.141 - 1.656 0.246 - 178.3 1 2 0 -0.0014 11 0 0 0 2.41E+06 1.40E+06 - - - 2.222 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.15561.15561.2 0.168 14-Sep R.LLFGPTVR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 911.5468 0.92 12336 15561 2 911.547912 456.7807 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3231.2 - 2.91E+06 - - - 1.2111 - 1.393 0.187 - 241.4 1 2 0 0.0011 8 0 0 0 5.71E+07 6.19E+07 - - - 1.4215 0.8679 230117_WJC_METTL3_WT_vs_EV_F02.15562.15562.2 5.39 16-May R.VVLGEFGVR[166.11].N "sp|O15160|RPAC1_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 6 984.5632 8.39 12337 15562 2 984.563537 493.2889 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 5.97 3231.3 - 6.56E+06 - - - 0.3565 - 0.936 0.005 - 71.5 1 2 0 0.0004 9 0 0 0 6.50E+08 7.74E+07 - - - -1.1135 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.15563.15563.2 0.0157 14-Jul R.LGDLVWGK.L "sp|Q49A26|GLYR1_HUMAN,sp|Q9UBC3|DNM3B_HUMAN,tr|K7EQB2|K7EQB2_HUMAN,tr|K7ELL0|K7ELL0_HUMAN" 4 886.4913 0.8 12338 15563 2 886.491891 444.2529 Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4 5.84 3231.3 - 2.58E+06 - - - 0.7197 - 1.478 0.331 - 127.1 1 2 0 0.0006 8 0 0 0 5.02E+07 6.25E+07 - - - 2.6639 0.999 230117_WJC_METTL3_WT_vs_EV_F02.15565.15565.2 0.0169 16-Aug K.LLPDTILEK[136.11].L "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1048.626 0.81 12340 15565 2 1048.625766 525.3203 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 4.37 3231.5 - 1.15E+06 - - - -0.1869 - 1.551 0.354 - 161.6 1 2 0 -0.0002 9 0 0 0 8.71E+07 1.08E+08 - - - 2.9253 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.15566.15566.2 0.073 16-Jul R.LQDLLLGPK.A sp|Q8N201|INT1_HUMAN 1 995.6015 1.53 12341 15566 2 995.602368 498.808 Integrator complex subunit 1 OS=Homo sapiens OX=9606 GN=INTS1 PE=1 SV=2 5.84 3231.6 - 860939 - - - 0.8397 - 1.187 0.227 - 101.7 1 2 0 0.0008 9 0 0 0 8.50E+06 5.55E+06 - - - 1.2133 0.9938 230117_WJC_METTL3_WT_vs_EV_F02.15568.15568.2 0.9 22-Jun R.LLETC[160.03]SIALVGK[136.11].Y "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN,tr|A0A3B3ISY3|A0A3B3ISY3_HUMAN" 7 1310.7359 2.82 12343 15568 2 1310.739424 656.3752 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 5.99 3231.9 - 141010 - - - 2.6703 - 1.234 0.208 - 84.7 1 2 0 0.0035 12 0 0 0 3.62E+06 1.29E+06 - - - 1.1294 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.15570.15570.2 0.225 12-Jul K.DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 844.4682 1.82 12344 15570 2 844.469101 423.2414 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.84 3232.1 - 1.36E+07 - - - 1.0397 - 1.245 0.258 - 246.5 1 2 0 0.0009 7 0 0 0 1.20E+09 6.57E+08 - - - 1.6407 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.15571.15571.2 0.111 12-Aug K.YIQELWR.K "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1006.5236 0.77 12345 15571 2 1006.52432 504.2691 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 6 3232.2 - 6.69E+06 - - - 0.6994 - 1.615 0.317 - 275 1 2 0 0.0007 7 0 0 0 1.03E+08 1.34E+08 - - - 2.9009 0.9733 230117_WJC_METTL3_WT_vs_EV_F02.15572.15572.2 1.58 14-Jul R.LLPEQLIK[136.11].E "sp|Q92621|NU205_HUMAN,sp|Q8TBZ9|TEX47_HUMAN" 2 960.6099 1.35 12346 15572 2 960.612551 481.3122 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 6 3232.3 - 1.71E+06 - - - 2.741 - 0.955 0.163 - 83.3 1 2 0 0.0026 8 0 0 0 5.25E+07 3.88E+07 - - - 0.1052 0.999 230117_WJC_METTL3_WT_vs_EV_F02.15577.15577.2 0.0164 22-Aug R.LLETC[160.03]SIALVGK.Y "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN,tr|A0A3B3ISY3|A0A3B3ISY3_HUMAN" 7 1302.7217 2.94 12351 15577 2 1302.727139 652.3681 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 5.99 3232.9 - 247340 - - - 4.1567 - 1.836 0.512 - 168.7 1 2 0 0.0054 12 0 0 0 3.78E+06 1.29E+06 - - - 4.4196 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.15586.15586.2 0.0468 12-Jun M.GVPAFFR.W sp|Q9H0D6|XRN2_HUMAN 1 792.4283 0.83 12358 15586 2 792.428828 397.2214 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 3234 - 528540 - - - 0.718 - 1.168 0.271 - 147.4 1 2 0 0.0006 7 0 0 0 1.64E+08 1.97E+08 - - - 1.5345 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.15587.15587.2 0.064 14-Aug R.YVLSSYLR.C "sp|Q9BRT9|SLD5_HUMAN,tr|E5RH56|E5RH56_HUMAN,tr|E5RFF9|E5RFF9_HUMAN" 3 999.5389 1.89 12359 15587 2 999.539974 500.7767 DNA replication complex GINS protein SLD5 OS=Homo sapiens OX=9606 GN=GINS4 PE=1 SV=1 8.59 3234.1 - 409945 - - - 1.0425 - 1.568 0.331 - 177.4 1 2 0 0.001 8 0 0 0 8.62E+06 4.56E+06 - - - 2.842 0.999 230117_WJC_METTL3_WT_vs_EV_F02.15589.15589.2 0.00611 22-Jul K.NYIQGINLVQAK.K "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1359.7511 3.39 12361 15589 2 1359.752107 680.8828 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 8.59 3234.3 - 90975.4 - - - 0.7773 - 1.42 0.333 - 116 1 2 0 0.0011 12 0 0 0 4.74E+06 1.40E+06 - - - 2.4228 0.9966 230117_WJC_METTL3_WT_vs_EV_F02.15592.15592.2 0.183 14-Jul R.LLFGPTVR.L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 901.5385 0.77 12362 15592 2 901.539521 451.7765 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3234.7 - 4.28E+06 - - - 1.0904 - 1.352 0.18 - 136.4 1 2 0 0.001 8 0 0 0 5.76E+07 7.48E+07 - - - 1.2797 0.9774 230117_WJC_METTL3_WT_vs_EV_F02.15594.15594.2 0.363 14-Jul K.LAVSSLLR.V "sp|Q7Z3U7|MON2_HUMAN,tr|A0A286YFF8|A0A286YFF8_HUMAN" 2 857.5335 1.57 12364 15594 2 857.536895 429.774 Protein MON2 homolog OS=Homo sapiens OX=9606 GN=MON2 PE=1 SV=3 9.75 3235 - 598494 - - - 4.015 - 1.454 0.083 - 116.3 1 2 0 0.0034 8 0 0 0 9.75E+06 6.20E+06 - - - 0.7819 0.9938 230117_WJC_METTL3_WT_vs_EV_F02.15599.15599.2 0.0336 14-Aug K.YYVLNALK.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 982.5488 2.37 12367 15599 2 982.548866 492.2817 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.5 3235.7 - 4.45E+06 - - - 0.0997 - 1.18 0.206 - 164.1 1 2 0 0.0001 8 0 0 0 1.18E+08 4.97E+07 - - - 1.0617 0.9896 230117_WJC_METTL3_WT_vs_EV_F02.15600.15600.2 0.475 16-May K.LITWSPVC[160.03]R[166.11].N "sp|P07203|GPX1_HUMAN,tr|A0A2R8Y6B6|A0A2R8Y6B6_HUMAN" 2 1140.5989 1.84 12368 15600 2 1140.601211 571.3067 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 8.25 3235.8 - 170558 - - - 2.0086 - 1.166 0.158 - 62.6 2 2 0 0.0023 9 0 0 0 9.34E+06 5.07E+06 - - - 0.5171 0.9966 230117_WJC_METTL3_WT_vs_EV_F02.15601.15601.2 0.0118 16-Sep R.VLGMTLIQK.C sp|Q04760|LGUL_HUMAN 1 1001.5943 1.22 12369 15601 2 1001.597966 501.8044 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3235.9 - 629315 - - - 3.6222 - 1.69 0.215 - 194.9 1 2 0 0.0036 9 0 0 0 2.58E+07 2.11E+07 - - - 2.1459 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.15602.15602.2 0.0607 18-Nov K.LIESAEELIR.D "sp|Q13217|DNJC3_HUMAN,tr|X6R9L0|X6R9L0_HUMAN" 2 1171.6449 1.86 12370 15602 2 1171.644114 586.8297 DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1 4.25 3236 - 500575 - - - -0.6307 - 1.863 0.206 - 336 1 2 0 -0.0007 10 0 0 0 8.48E+06 4.56E+06 - - - 2.299 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15603.15603.2 0.0392 18-Nov K.LIESAEELIR[166.11].D "sp|Q13217|DNJC3_HUMAN,tr|X6R9L0|X6R9L0_HUMAN" 2 1181.6531 1.86 12371 15603 2 1181.656293 591.8338 DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1 4.25 3236.1 - 316917 - - - 2.6827 - 2.313 0.395 - 310.9 1 2 0 0.0032 10 0 0 0 8.48E+06 4.56E+06 - - - 4.2981 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.15609.15609.2 0.00169 18-Sep R.LVPC[160.03]ILEAAK.Q "sp|Q96ER3|SAAL1_HUMAN,tr|H0YCN7|H0YCN7_HUMAN,tr|H0YEK5|H0YEK5_HUMAN,tr|J3KND1|J3KND1_HUMAN,tr|E9PMD2|E9PMD2_HUMAN,tr|E9PRZ1|E9PRZ1_HUMAN" 6 1112.6264 1.16 12375 15609 2 1112.628002 557.3205 Protein SAAL1 OS=Homo sapiens OX=9606 GN=SAAL1 PE=1 SV=2 5.99 3236.9 - 734450 - - - 1.4695 - 1.63 0.378 - 224.3 1 2 0 0.0016 10 0 0 0 6.40E+06 5.51E+06 - - - 3.1962 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.15611.15611.2 0.0156 16-Oct R.VLGMTLIQK[136.11].C sp|Q04760|LGUL_HUMAN 1 1009.6085 1.25 12377 15611 2 1009.611061 505.8115 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3237 - 2.96E+06 - - - 2.499 - 1.582 0.251 - 261.2 1 2 0 0.0025 9 0 0 0 2.63E+07 2.11E+07 - - - 2.2211 0.9755 230117_WJC_METTL3_WT_vs_EV_F02.15613.15613.2 0.000222 16-Jul K.YMTDGMLLR.E "sp|Q14562|DHX8_HUMAN,sp|O60231|DHX16_HUMAN,sp|O43143|DHX15_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|F5H658|F5H658_HUMAN" 5 1098.5202 1.16 12379 15613 2 1098.526027 550.2674 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 5.84 3237.1 - 850867 - - - 5.3162 - 1.316 0.213 - 134.1 1 2 0 0.0058 9 0 0 0 2.39E+07 2.05E+07 - - - 1.4068 0.9704 230117_WJC_METTL3_WT_vs_EV_F02.15616.15616.2 0.213 14-Jun K.MLLSLPEK[136.11].V "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 937.5398 1.11 12382 15616 2 937.544989 469.7772 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 5.75 3237.5 - 285368 - - - 5.5454 - 1.262 0.24 - 72.2 2 2 0 0.0052 8 0 0 0 1.24E+07 1.11E+07 - - - 1.3793 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.15629.15629.2 0.00402 16-Sep R.LFEGNALLR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1031.5764 0.88 12391 15629 2 1031.578365 516.7955 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3239.1 - 4.08E+06 - - - 1.9242 - 1.768 0.447 - 286.3 1 2 0 0.002 9 0 0 0 8.98E+08 1.03E+09 - - - 3.9905 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.15634.15634.2 0.166 14-Aug K.MLLSLPEK.V "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 929.5256 1.11 12396 15634 2 929.52672 465.7701 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 5.75 3239.7 - 495091 - - - 1.2157 - 1.668 0.191 - 213.7 1 2 0 0.0011 8 0 0 0 1.24E+07 1.11E+07 - - - 1.9944 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.15635.15635.2 0.00306 16-Aug K.LISEEDLLR.K "sp|P01106|MYC_HUMAN,tr|A0A087WUS5|A0A087WUS5_HUMAN,tr|A0A494C1T8|A0A494C1T8_HUMAN,tr|H0YBT0|H0YBT0_HUMAN" 4 1086.5921 0.13 12397 15635 2 1086.59425 544.3033 Myc proto-oncogene protein OS=Homo sapiens OX=9606 GN=MYC PE=1 SV=1 4.14 3239.8 - 494077 - - - 1.9879 - 1.605 0.361 - 168.8 1 2 0 0.0022 9 0 0 0 8.33E+06 6.44E+07 - - - 3.0754 0.995 230117_WJC_METTL3_WT_vs_EV_F02.15637.15637.2 6.39E-05 18-Oct K.LLANMVYQYK.G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1241.6478 2.02 12399 15637 2 1241.642795 621.8312 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3240.1 - 286304 - - - -4.0551 - 1.836 0.498 - 285.6 1 2 0 -0.005 10 0 0 0 2.12E+07 1.05E+07 - - - 4.4136 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.15640.15640.2 0.000598 16-Jul R.LFEGNALLR[166.11].R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1041.5847 0.87 12400 15640 2 1041.583964 521.7996 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3240.5 - 1.13E+07 - - - -0.6586 - 1.714 0.394 - 138.1 1 2 0 -0.0007 9 0 0 0 8.93E+08 1.02E+09 - - - 3.5097 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.15642.15642.2 0.00455 16-Sep R.FLPSPVVIK[136.11].K "sp|Q13618|CUL3_HUMAN,tr|H7C399|H7C399_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 3 1006.6307 0.63 12402 15642 2 1006.632672 504.3226 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 8.75 3240.7 - 1.67E+06 - - - 2.0047 - 1.262 0.317 - 237.6 1 2 0 0.002 9 0 0 0 3.17E+07 5.06E+07 - - - 2.0549 0.9884 230117_WJC_METTL3_WT_vs_EV_F02.15648.15648.2 1.02 14-Jun R.AFLLDPDR.C sp|Q9BTY7|HGH1_HUMAN 1 945.492 1.42 12408 15648 2 945.493571 473.7533 Protein HGH1 homolog OS=Homo sapiens OX=9606 GN=HGH1 PE=1 SV=1 4.21 3241.5 - 1.60E+06 - - - 1.6806 - 1.166 0.156 - 73.6 4 2 0 0.0016 8 0 0 0 8.10E+06 5.71E+06 - - - 0.387 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.15650.15650.2 0.00945 18-Aug K.LLANMVYQYK[136.11].G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1249.662 1.98 12410 15650 2 1249.662369 625.8383 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3241.7 - 268350 - - - 0.2713 - 1.371 0.325 - 125.8 1 2 0 0.0003 10 0 0 0 2.12E+07 1.07E+07 - - - 2.3221 0.9885 230117_WJC_METTL3_WT_vs_EV_F02.15651.15651.2 1.62 14-Nov R.IAVPVLVR[166.11].D sp|P52952|NKX25_HUMAN 1 875.5832 1.95 12411 15651 2 875.585849 438.7989 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 9.75 3241.9 - 240017 - - - 3.0334 - 1.57 0.056 - 567 1 2 0 0.0027 8 0 0 0 1.98E+07 1.02E+07 - - - 0.8142 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.15656.15656.2 0.000575 14-Sep K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 1.77 12414 15656 2 895.481814 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3242.5 - 1.12E+07 - - - 1.6304 - 1.874 0.428 - 209.8 1 2 0 0.0015 8 0 0 0 2.50E+09 1.41E+09 - - - 4.096 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.15659.15659.2 0.00115 20-Dec R.VIGTLLGTVDK[136.11].H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1122.674 1.11 12417 15659 2 1122.675173 562.3443 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3242.7 - 2.05E+06 - - - 1.0671 - 2.474 0.411 - 347.6 1 2 0 0.0012 11 0 0 0 9.32E+07 8.37E+07 - - - 4.5268 1 230117_WJC_METTL3_WT_vs_EV_F02.15660.15660.2 1.31E-05 20-Dec R.VIGTLLGTVDK.H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1114.6598 1.12 12418 15660 2 1114.661755 558.3372 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3242.8 - 1.85E+06 - - - 1.7763 - 2.459 0.52 - 302.6 1 2 0 0.002 11 0 0 0 9.38E+07 8.39E+07 - - - 5.3151 0.9356 230117_WJC_METTL3_WT_vs_EV_F02.15663.15663.2 0.109 12-Aug L.FGDLLLK[136.11].Q "sp|Q15147|PLCB4_HUMAN,sp|Q6P2Q9|PRP8_HUMAN,tr|A0A7P0MRI8|A0A7P0MRI8_HUMAN" 3 812.4887 1.24 12421 15663 2 812.489864 407.2516 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4 PE=1 SV=3" 5.84 3243.2 - 538671 - - - 1.3822 - 1.81 0.219 - 152.4 1 1 0 0.0011 7 0 0 0 1.44E+08 1.16E+08 - - - 2.5382 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.15664.15664.2 0.131 18-Sep R.IVLVDDSIVR.G sp|Q06203|PUR1_HUMAN 1 1127.655 2.33 12422 15664 2 1127.657731 564.8348 Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1 4.21 3243.3 - 374996 - - - 2.4006 - 1.847 0.23 - 226.1 1 2 0 0.0027 10 0 0 0 3.98E+07 1.71E+07 - - - 2.4516 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.15668.15668.2 0.882 14-Aug R.SLVSGLIR[166.11].L sp|Q92616|GCN1_HUMAN 1 853.5261 1.11 12424 15668 2 853.526299 427.7703 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.47 3243.8 - 1.53E+06 - - - 0.266 - 1.489 0.172 - 236.5 1 2 0 0.0002 8 0 0 0 4.75E+07 4.27E+07 - - - 1.512 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.15669.15669.2 0.0153 16-Jun R.FLPSPVVIK.K "sp|Q13618|CUL3_HUMAN,tr|H7C399|H7C399_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 3 998.6165 0.62 12425 15669 2 998.617603 500.3155 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 8.75 3243.9 - 2.68E+06 - - - 1.1506 - 1.231 0.295 - 97.4 1 2 0 0.0011 9 0 0 0 3.17E+07 5.08E+07 - - - 1.8208 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.15671.15671.2 0.11 14-Sep R.IAVPVLVR.D sp|P52952|NKX25_HUMAN 1 865.5749 1.86 12427 15671 2 865.575017 433.7947 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 9.75 3244 - 1.24E+06 - - - 0.1086 - 1.682 0.319 - 354.2 1 2 0 0.0001 8 0 0 0 1.89E+07 1.02E+07 - - - 2.9654 0.995 230117_WJC_METTL3_WT_vs_EV_F02.15672.15672.2 0.0314 14-Aug K.VFNLGVYR[166.11].R "sp|O60825|F262_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN" 2 976.537 0.59 12428 15672 2 976.536077 489.2758 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 8.72 3244.1 - 1.18E+06 - - - -0.9155 - 1.642 0.162 - 240.9 1 2 0 -0.0009 8 0 0 0 2.65E+07 4.52E+07 - - - 1.7329 1 230117_WJC_METTL3_WT_vs_EV_F02.15674.15674.2 6.09E-05 20-Nov R.LFSGDVVLTAR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1186.6585 1.01 12430 15674 2 1186.659276 594.3365 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3244.4 - 661558 - - - 0.6177 - 2.227 0.506 - 374.1 1 2 0 0.0007 11 0 0 0 2.05E+08 2.02E+08 - - - 4.944 0.997 230117_WJC_METTL3_WT_vs_EV_F02.15676.15676.2 0.00269 18-Sep R.IVLVDDSIVR[166.11].G sp|Q06203|PUR1_HUMAN 1 1137.6633 2.08 12432 15676 2 1137.660231 569.8389 Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1 4.21 3244.6 - 406438 - - - -2.6924 - 1.686 0.428 - 233 1 2 0 -0.0031 10 0 0 0 3.56E+07 1.71E+07 - - - 3.6593 1 230117_WJC_METTL3_WT_vs_EV_F02.15677.15677.2 4.32E-05 13/20 R.LFSGDVVLTAR.D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1176.6503 1.01 12433 15677 2 1176.650341 589.3324 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3244.8 - 387892 - - - 0.0578 - 2.438 0.564 - 534.4 1 2 0 0.0001 11 0 0 0 2.05E+08 2.02E+08 - - - 5.6175 0.994 230117_WJC_METTL3_WT_vs_EV_F02.15680.15680.2 0.713 14-Aug K.NLYIISVK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 956.5786 1.32 12434 15680 2 956.57979 479.2966 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3245.2 - 1.10E+06 - - - 1.2252 - 1.354 0.119 - 187.9 1 2 0 0.0012 8 0 0 0 3.25E+09 2.46E+09 - - - 0.8336 0.981 230117_WJC_METTL3_WT_vs_EV_F02.15681.15681.2 0.486 14-Jul R.NLEIQSWR[166.11].S "sp|O94823|AT10B_HUMAN,tr|A0A2R8YDI5|A0A2R8YDI5_HUMAN" 2 1054.5435 0.73 12435 15681 2 1054.543842 528.279 Phospholipid-transporting ATPase VB OS=Homo sapiens OX=9606 GN=ATP10B PE=1 SV=2 6 3245.3 - 458951 - - - 0.312 - 1.367 0.028 - 144.9 1 2 0 0.0003 8 0 0 0 2.04E+07 2.80E+07 - - - 0.1905 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.15686.15686.2 0.008 14-Sep K.NLYIISVK.G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 948.5644 1.32 12440 15686 2 948.564585 475.2895 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3245.9 - 799064 - - - 0.1761 - 1.551 0.201 - 300.5 1 2 0 0.0002 8 0 0 0 3.25E+09 2.46E+09 - - - 1.8492 1 230117_WJC_METTL3_WT_vs_EV_F02.15687.15687.2 0.000297 26-Dec K.VLEQLTGQTPVFSK.A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1545.8403 1.71 12441 15687 2 1545.845744 773.9274 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3246 - 623552 - - - 3.5482 - 2.614 0.478 - 184.7 1 2 0 0.0055 14 0 0 0 4.86E+06 2.85E+06 - - - 4.9811 1 230117_WJC_METTL3_WT_vs_EV_F02.15688.15688.2 3.27E-06 26-Oct K.VLEQLTGQTPVFSK[136.11].A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1553.8545 1.71 12442 15688 2 1553.854543 777.9345 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3246.1 - 405009 - - - 0.0541 - 2.241 0.525 - 304.4 1 2 0 0.0001 14 0 0 0 4.86E+06 2.85E+06 - - - 4.9436 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15690.15690.2 0.00123 22-Oct R.VLVTGATGLLGR[166.11].A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1165.7058 1.55 12444 15690 2 1165.708528 583.8602 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3246.4 - 229827 - - - 2.3162 - 1.907 0.482 - 287.7 1 2 0 0.0027 12 0 0 0 2.27E+07 1.46E+07 - - - 4.2987 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.15691.15691.2 0.0416 18-Jun R.LIYTAGGYFR.Q sp|Q14145|KEAP1_HUMAN 1 1159.6026 2.3 12445 15691 2 1159.604714 580.8086 Kelch-like ECH-associated protein 1 OS=Homo sapiens OX=9606 GN=KEAP1 PE=1 SV=2 8.59 3246.5 - 233062 - - - 1.8274 - 1.116 0.286 - 82.9 1 2 0 0.0021 10 0 0 0 7.30E+06 3.17E+06 - - - 1.4591 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.15694.15694.2 0.0109 14-Jul K.FVADGIFK[136.11].A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 903.4946 1.77 12446 15694 2 903.495134 452.7546 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3246.9 - 3.96E+07 - - - 0.642 - 1.448 0.343 - 129.3 1 2 0 0.0006 8 0 0 0 2.51E+09 1.41E+09 - - - 2.6907 0.9239 230117_WJC_METTL3_WT_vs_EV_F02.15695.15695.2 0.152 12-Sep L.FGDLLLK.Q "sp|Q15147|PLCB4_HUMAN,sp|Q6P2Q9|PRP8_HUMAN,tr|A0A7P0MRI8|A0A7P0MRI8_HUMAN" 3 804.4745 1.25 12447 15695 2 804.475216 403.2445 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4 PE=1 SV=3" 5.84 3247 - 3.12E+06 - - - 0.8391 - 1.736 0.219 - 211.2 1 1 0 0.0007 7 0 0 0 1.44E+08 1.16E+08 - - - 2.406 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.15701.15701.2 0.0014 22-Nov R.VLVTGATGLLGR.A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1155.6976 1.55 12453 15701 2 1155.699182 578.8561 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3247.5 - 427260 - - - 1.4052 - 2.18 0.464 - 332 1 2 0 0.0016 12 0 0 0 2.27E+07 1.46E+07 - - - 4.5181 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.15703.15703.2 0.0176 18-Jun R.LIYTAGGYFR[166.11].Q sp|Q14145|KEAP1_HUMAN 1 1169.6109 2.3 12455 15703 2 1169.613736 585.8127 Kelch-like ECH-associated protein 1 OS=Homo sapiens OX=9606 GN=KEAP1 PE=1 SV=2 8.59 3247.7 - 192198 - - - 2.4547 - 1.328 0.307 - 70.4 1 2 0 0.0029 10 0 0 0 7.30E+06 3.17E+06 - - - 2.0994 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.15706.15706.2 0.0858 14-Jul R.LLPSLIGR[166.11].H "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 4 877.5625 0.76 12456 15706 2 877.564222 439.7885 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 9.75 3248.1 - 2.99E+06 - - - 2.0101 - 1.184 0.278 - 190.4 1 2 0 0.0018 8 0 0 0 5.82E+07 7.62E+07 - - - 1.6031 0.9919 230117_WJC_METTL3_WT_vs_EV_F02.15707.15707.2 0.218 14-Jul R.LLPSLIGR.H "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 4 867.5542 0.76 12457 15707 2 867.554283 434.7844 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 9.75 3248.2 - 1.74E+06 - - - 0.1095 - 1.367 0.118 - 183.5 1 2 0 0.0001 8 0 0 0 5.82E+07 7.62E+07 - - - 0.8554 0.9954 230117_WJC_METTL3_WT_vs_EV_F02.15709.15709.2 0.955 14-Jul K.TAVLTLIR.E "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 8 885.5648 1.41 12459 15709 2 885.565016 443.7897 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 9.41 3248.3 - 2.02E+06 - - - 0.297 - 1.378 0.165 - 203.8 1 2 0 0.0003 8 0 0 0 1.34E+08 9.50E+07 - - - 1.2266 0.9836 230117_WJC_METTL3_WT_vs_EV_F02.15710.15710.2 3.11 12-Aug K.LLTSLLK[136.11].Q sp|O60763|USO1_HUMAN 1 794.5357 0.47 12460 15710 2 794.535342 398.2751 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 8.75 3248.4 - 1.69E+06 - - - -0.4393 - 1.094 0.169 - 157.5 1 2 0 -0.0003 7 0 0 0 1.33E+07 2.83E+07 - - - 0.5738 0.8492 230117_WJC_METTL3_WT_vs_EV_F02.15711.15711.2 4.29 12-Jun K.LLTSLLK.Q sp|O60763|USO1_HUMAN 1 786.5215 0.55 12461 15711 2 786.523466 394.268 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 8.75 3248.5 - 1.68E+06 - - - 2.5111 - 0.969 0.018 - 76.8 3 2 0 0.002 7 0 0 0 1.33E+07 2.43E+07 - - - -1.1396 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.15712.15712.2 3.20E-05 14-Sep R.LFC[160.03]VGFTK.K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 970.4946 0.84 12462 15712 2 970.493727 486.2546 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.22 3248.5 - 1.27E+06 - - - -0.9243 - 1.75 0.365 - 218.7 1 2 0 -0.0009 8 0 0 0 3.02E+08 3.59E+08 - - - 3.4244 0.99 230117_WJC_METTL3_WT_vs_EV_F02.15713.15713.2 0.468 16-Aug R.LWGEPVNLR.E "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 1082.5873 0.91 12463 15713 2 1082.585854 542.3009 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 6 3248.7 - 769719 - - - -1.3163 - 1.545 0.145 - 183.2 1 2 0 -0.0014 9 0 0 0 1.02E+07 1.12E+07 - - - 1.3701 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.15714.15714.2 0.104 14-Jul R.FVDGLTFK.V "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 925.4909 0.9 12464 15714 2 925.49155 463.7527 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.84 3248.7 - 742948 - - - 0.6818 - 1.274 0.298 - 122.2 1 2 0 0.0006 8 0 0 0 1.12E+07 1.25E+07 - - - 1.9722 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.15718.15718.2 0.000401 14-Sep R.LFC[160.03]VGFTK[136.11].K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 978.5088 0.84 12466 15718 2 978.508853 490.2617 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.22 3249.3 - 5.07E+06 - - - 0.0296 - 1.679 0.402 - 255.3 1 2 0 0 8 0 0 0 3.02E+08 3.59E+08 - - - 3.573 0.9685 230117_WJC_METTL3_WT_vs_EV_F02.15720.15720.2 1.98 14-Jun R.SLVSGLIR.L sp|Q92616|GCN1_HUMAN 1 843.5178 1.11 12468 15720 2 843.518747 422.7662 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.47 3249.4 - 5.40E+06 - - - 1.1203 - 1.152 0.051 - 136.3 2 2 0 0.0009 8 0 0 0 4.75E+07 4.27E+07 - - - -0.2903 0.9954 230117_WJC_METTL3_WT_vs_EV_F02.15727.15727.2 0.0653 16-Jul K.LIPPQDILR[166.11].D sp|Q96A65|EXOC4_HUMAN 1 1073.6472 1.51 12473 15727 2 1073.646568 537.8309 Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1 5.84 3250.3 - 275346 - - - -0.6352 - 1.21 0.28 - 115.9 1 2 0 -0.0007 9 0 0 0 9.76E+06 6.48E+06 - - - 1.6603 0.9922 230117_WJC_METTL3_WT_vs_EV_F02.15731.15731.2 0.369 14-Jul K.AVIELLEK[136.11].S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|H0Y327|H0Y327_HUMAN,tr|Q5JYA8|Q5JYA8_HUMAN,tr|Q5JYA3|Q5JYA3_HUMAN" 6 921.5626 2.13 12475 15731 2 921.563272 461.7886 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.53 3250.8 - 527796 - - - 0.6923 - 1.449 0.075 - 149 1 2 0 0.0006 8 0 0 0 5.89E+07 2.76E+07 - - - 0.7133 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.15734.15734.2 0.0213 14-Sep R.TVETLLLR.F "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 6 943.5702 0.65 12478 15734 2 943.570999 472.7924 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 5.66 3251.1 - 353948 - - - 0.8129 - 1.725 0.225 - 257.8 1 2 0 0.0008 8 0 0 0 8.92E+07 1.38E+08 - - - 2.347 0.9856 230117_WJC_METTL3_WT_vs_EV_F02.15742.15742.2 0.115 16-Sep K.EALEAVLIK[136.11].G "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 992.5997 1.88 12484 15742 2 992.605269 497.3072 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 4.53 3252.1 - 298715 - - - 5.5622 - 1.487 0.25 - 182.9 1 2 0 0.0055 9 0 0 0 2.01E+07 1.07E+07 - - - 2.0336 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.15749.15749.2 0.437 12-Aug R.LSAILFK.L "sp|Q9NSV4|DIAP3_HUMAN,sp|Q12830|BPTF_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|J3KSK9|J3KSK9_HUMAN,tr|J3QQQ8|J3QQQ8_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN" 7 790.4953 2.39 12489 15749 2 790.495687 396.2549 Protein diaphanous homolog 3 OS=Homo sapiens OX=9606 GN=DIAPH3 PE=1 SV=4 8.75 3253 - 589921 - - - 0.5199 - 1.624 0.136 - 174.1 1 2 0 0.0004 7 0 0 0 1.06E+07 4.45E+06 - - - 1.5818 0.9239 230117_WJC_METTL3_WT_vs_EV_F02.15751.15751.2 1.78 12-Apr K.VLFTC[160.03]FK[136.11].R "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 921.4874 1.86 12491 15751 2 921.488228 461.751 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 8.19 3253.2 - 995190 - - - 0.9409 - 0.95 0.108 - 49.3 15 2 0 0.0009 7 0 0 0 1.82E+07 9.80E+06 - - - -0.8495 0.9953 230117_WJC_METTL3_WT_vs_EV_F02.15754.15754.2 0.0536 16-Jul R.FFMGNQVLK[136.11].V sp|P13010|XRCC5_HUMAN 1 1090.5725 0.8 12492 15754 2 1090.573211 546.2935 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3253.6 - 528715 - - - 0.6639 - 1.253 0.19 - 96.5 1 2 0 0.0007 9 0 0 0 5.15E+07 6.42E+07 - - - 1.0966 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.15755.15755.2 1.95 18-Sep K.ATLLLESGIR[166.11].L "sp|O60524|NEMF_HUMAN,tr|G3V547|G3V547_HUMAN,tr|G3V5V3|G3V5V3_HUMAN,tr|G3V4D9|G3V4D9_HUMAN" 4 1081.6371 1.02 12493 15755 2 1081.63651 541.8258 Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4 6.05 3253.7 - 366781 - - - -0.5261 - 1.803 0.163 - 184.7 1 2 0 -0.0006 10 0 0 0 7.72E+06 7.59E+06 - - - 1.8901 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.15756.15756.2 0.00488 14-Jul R.ELYPVEFR.N "sp|Q5BJF2|SGMR2_HUMAN,tr|J3KT68|J3KT68_HUMAN" 2 1051.5338 1.22 12494 15756 2 1051.532229 526.7742 Sigma intracellular receptor 2 OS=Homo sapiens OX=9606 GN=TMEM97 PE=1 SV=1 4.53 3253.8 - 444072 - - - -1.5378 - 1.397 0.405 - 206.1 1 2 0 -0.0016 8 0 0 0 1.72E+07 1.41E+07 - - - 3.0401 0.9902 230117_WJC_METTL3_WT_vs_EV_F02.15760.15760.2 0.128 16-Jul R.FFMGNQVLK.V sp|P13010|XRCC5_HUMAN 1 1082.5583 0.8 12496 15760 2 1082.556587 542.2864 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3254.3 - 522659 - - - -1.5704 - 1.303 0.232 - 105.7 1 2 0 -0.0017 9 0 0 0 5.15E+07 6.42E+07 - - - 1.5197 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.15762.15762.2 0.000443 18-Sep R.LVPLQEEIYR.K "sp|Q2NKX8|ERC6L_HUMAN,tr|B5MDQ0|B5MDQ0_HUMAN" 2 1258.6921 5.25 12498 15762 2 1258.692338 630.3533 DNA excision repair protein ERCC-6-like OS=Homo sapiens OX=9606 GN=ERCC6L PE=1 SV=1 4.53 3254.6 - 347551 - - - 0.1589 - 1.734 0.405 - 379.3 1 2 0 0.0002 10 0 0 0 7.70E+06 1.47E+06 - - - 3.5687 0.9578 230117_WJC_METTL3_WT_vs_EV_F02.15767.15767.2 0.331 12-May K.FVSELWK.D sp|P35579|MYH9_HUMAN 1 907.4804 0.72 12501 15767 2 907.481608 454.7475 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6 3255.2 - 1.65E+06 - - - 1.3818 - 1.161 0 - 68.5 1 2 0 0.0013 7 0 0 0 9.27E+07 1.29E+08 - - - -0.4864 0.999 230117_WJC_METTL3_WT_vs_EV_F02.15769.15769.2 0.0397 14-Jul K.EMVELPLR[166.11].H "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN" 10 995.5349 0.68 12503 15769 2 995.535169 498.7747 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.53 3255.4 - 474605 - - - 0.2471 - 1.606 0.305 - 189.1 1 2 0 0.0002 8 0 0 0 1.64E+07 2.41E+07 - - - 2.7225 0.9946 230117_WJC_METTL3_WT_vs_EV_F02.15772.15772.2 0.379 14-Jun K.EMVELPLR.H "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN" 10 985.5267 0.68 12504 15772 2 985.529079 493.7706 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.53 3255.8 - 693063 - - - 2.4616 - 1.365 0.158 - 97.5 1 2 0 0.0024 8 0 0 0 1.64E+07 2.40E+07 - - - 1.1457 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.15773.15773.2 0.0493 18-Oct R.GLIENPALLR[166.11].W sp|O95168|NDUB4_HUMAN 1 1104.6531 1.22 12505 15773 2 1104.652156 553.3338 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3 6 3255.9 - 461667 - - - -0.822 - 2.113 0.3 - 245 1 2 0 -0.0009 10 0 0 0 4.28E+07 3.51E+07 - - - 3.3447 0.9934 230117_WJC_METTL3_WT_vs_EV_F02.15774.15774.2 0.873 16-Aug R.ILPQDVILK[136.11].F "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1045.6627 0.97 12506 15774 2 1045.662758 523.8386 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.84 3256 - 697833 - - - 0.0727 - 1.344 0.153 - 117.4 1 2 0 0.0001 9 0 0 0 3.87E+07 3.99E+07 - - - 1.0264 0.9841 230117_WJC_METTL3_WT_vs_EV_F02.15776.15776.2 0.0708 16-Aug R.YMVALQIAR[166.11].E sp|Q7KZ85|SPT6H_HUMAN 1 1073.5931 1.33 12508 15776 2 1073.593586 537.8038 Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2 8.75 3256.3 - 254042 - - - 0.4471 - 1.369 0.044 - 165.9 1 2 0 0.0005 9 0 0 0 9.13E+06 6.87E+06 - - - 0.2745 0.9951 230117_WJC_METTL3_WT_vs_EV_F02.15783.15783.2 0.541 16-Jul R.ILPQDVILK.F "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1037.6485 0.97 12511 15783 2 1037.649549 519.8315 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.84 3257.2 - 1.28E+06 - - - 1.0283 - 1.194 0.196 - 112.6 1 2 0 0.0011 9 0 0 0 3.87E+07 3.99E+07 - - - 1.0013 0.9408 230117_WJC_METTL3_WT_vs_EV_F02.15784.15784.2 0.0185 20-Aug K.MVLSGC[160.03]AIIVR.G sp|Q7KZF4|SND1_HUMAN 1 1217.6624 1.74 12512 15784 2 1217.670285 609.8385 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 8 3257.3 - 263468 - - - 6.4468 - 1.575 0.137 - 153.5 1 2 0 0.0078 11 0 0 0 3.97E+06 2.28E+06 - - - 1.2793 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.15799.15799.2 0.00464 18-Oct K.VPVLISPTLK[136.11].H sp|P42684|ABL2_HUMAN 1 1073.694 2.66 12520 15799 2 1073.695699 537.8543 Tyrosine-protein kinase ABL2 OS=Homo sapiens OX=9606 GN=ABL2 PE=1 SV=1 8.72 3259.2 - 290577 - - - 1.5992 - 1.473 0.391 - 208.4 1 2 0 0.0017 10 0 0 0 1.55E+07 5.84E+06 - - - 3.0095 0.9935 230117_WJC_METTL3_WT_vs_EV_F02.15807.15807.2 0.668 12-Jul K.SIELFYK[136.11].F sp|P78527|PRKDC_HUMAN 1 906.4942 1.14 12526 15807 2 906.495322 454.2544 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.72 3260.1 - 1.13E+06 - - - 1.2157 - 1.178 0.166 - 168.6 1 2 0 0.0011 7 0 0 0 1.93E+07 1.70E+07 - - - 0.7858 0.9681 230117_WJC_METTL3_WT_vs_EV_F02.15814.15814.2 0.85 12-Jun K.SIELFYK.F sp|P78527|PRKDC_HUMAN 1 898.48 0.5 12531 15814 2 898.482361 450.2473 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.72 3261 - 1.50E+06 - - - 2.6055 - 0.903 0.165 - 109.7 1 2 0 0.0023 7 0 0 0 2.78E+07 5.57E+07 - - - -0.0643 0.9948 230117_WJC_METTL3_WT_vs_EV_F02.15815.15815.2 0.904 12-Aug R.VLAAFLR.R "sp|Q9HB09|B2L12_HUMAN,sp|Q99607|ELF4_HUMAN,tr|M0R1Z8|M0R1Z8_HUMAN,tr|A0A087WU18|A0A087WU18_HUMAN,tr|I6LJZ9|I6LJZ9_HUMAN,tr|A0A087WSV0|A0A087WSV0_HUMAN,tr|I6LK00|I6LK00_HUMAN,tr|I6LJZ7|I6LJZ7_HUMAN,tr|M0R1K0|M0R1K0_HUMAN,tr|M0QZM6|M0QZM6_HUMAN" 10 788.4909 3.32 12532 15815 2 788.493172 395.2527 Bcl-2-like protein 12 OS=Homo sapiens OX=9606 GN=BCL2L12 PE=1 SV=1 9.72 3261.1 - 983581 - - - 2.9335 - 1.6 0.117 - 199.4 1 2 0 0.0023 7 0 0 0 2.65E+07 7.98E+06 - - - 1.3937 0.9918 230117_WJC_METTL3_WT_vs_EV_F02.15816.15816.2 0.0548 22-Aug K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.42 12533 15816 2 1287.761163 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3261.3 - 220466 - - - 2.5626 - 1.424 0.121 - 108.2 1 2 0 0.0033 12 0 0 0 1.66E+07 1.17E+07 - - - 0.8637 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.15821.15821.2 0.0754 20-Aug K.ALILVGGYGTR.L "sp|Q9Y5P6|GMPPB_HUMAN,tr|A0A7I2V691|A0A7I2V691_HUMAN,tr|A0A7I2V2Y5|A0A7I2V2Y5_HUMAN,tr|A0A7I2YQI5|A0A7I2YQI5_HUMAN,tr|A0A7I2V4B5|A0A7I2V4B5_HUMAN" 5 1118.6448 1.09 12536 15821 2 1118.644785 560.3297 Mannose-1-phosphate guanyltransferase beta OS=Homo sapiens OX=9606 GN=GMPPB PE=1 SV=2 8.79 3261.9 - 246347 - - - -0.008 - 1.941 0.217 - 146.2 1 2 0 0 11 0 0 0 1.02E+07 9.41E+06 - - - 2.4379 0.9908 230117_WJC_METTL3_WT_vs_EV_F02.15823.15823.2 0.00808 22-Aug K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.35 12538 15823 2 1277.753508 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3262.2 - 223284 - - - 3.064 - 1.606 0.096 - 111.4 1 2 0 0.0039 12 0 0 0 9.10E+06 6.76E+06 - - - 0.9953 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.15829.15829.2 0.0211 16-Sep R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 0.76 12542 15829 2 960.611605 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3263 - 1.01E+07 - - - 1.7562 - 1.838 0.23 - 251.2 1 2 0 0.0017 9 0 0 0 9.29E+09 1.22E+10 - - - 2.5002 0.9607 230117_WJC_METTL3_WT_vs_EV_F02.15832.15832.2 0.0291 18-Nov H.ILSPWGAEVK.A "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1098.6073 1.04 12545 15832 2 1098.609221 550.3109 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3263.3 - 838590 - - - 1.7067 - 1.965 0.311 - 334.4 1 1 0 0.0019 10 0 0 0 5.60E+07 5.37E+07 - - - 3.223 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.15837.15837.2 0.00205 20-Oct K.FSPAGPVLSIR[166.11].V "sp|Q13310|PABP4_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN" 4 1152.6531 1.18 12550 15837 2 1152.65878 577.3338 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.75 3264 - 147364 - - - 4.959 - 1.677 0.491 - 254.9 1 2 0 0.0057 11 0 0 0 8.41E+06 7.13E+06 - - - 4.0644 0.9768 230117_WJC_METTL3_WT_vs_EV_F02.15841.15841.2 1.64 12-May K.AFLFVNK.G sp|Q8N0X7|SPART_HUMAN 1 837.4749 1.39 12552 15841 2 837.476144 419.7447 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3264.5 - 8.77E+06 - - - 1.5153 - 1.144 0.096 - 128.9 4 2 0 0.0013 7 0 0 0 1.47E+08 1.06E+08 - - - -0.093 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15842.15842.2 9.40E-05 18-Oct K.IGDLGLATLK.R "sp|Q9H4A3|WNK1_HUMAN,sp|Q96J92|WNK4_HUMAN,sp|Q9Y3S1|WNK2_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A6PVV2|A6PVV2_HUMAN,tr|K7ENT7|K7ENT7_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 9 999.5964 2.04 12553 15842 2 999.599092 500.8055 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 5.84 3264.5 - 3.01E+06 - - - 2.6461 - 1.932 0.441 - 209.3 1 2 0 0.0026 10 0 0 0 7.53E+07 3.69E+07 - - - 4.1356 1 230117_WJC_METTL3_WT_vs_EV_F02.15843.15843.3 1.59E-06 21/64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 18.61 12554 15843 3 1786.985718 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3264.7 - 1.09E+06 - - - 1.577 - 3.736 0.51 - 440.2 1 2 0 0.0028 17 0 0 0 5.39E+07 2.89E+06 - - - 7.5549 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.15845.15845.2 0.00419 20-Aug K.FSPAGPVLSIR.V "sp|Q13310|PABP4_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN" 4 1142.6448 1.13 12556 15845 2 1142.645113 572.3297 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.75 3264.9 - 761972 - - - 0.2792 - 1.62 0.296 - 144.4 1 2 0 0.0003 11 0 0 0 8.41E+06 7.46E+06 - - - 2.5322 0.9792 230117_WJC_METTL3_WT_vs_EV_F02.15846.15846.2 5.93 12-Jul R.SVINLLR.N "sp|Q96AT9|RPE_HUMAN,sp|Q2QD12|RPEL1_HUMAN,tr|C9J6A7|C9J6A7_HUMAN" 3 813.5072 1.52 12557 15846 2 813.508678 407.7609 Ribulose-phosphate 3-epimerase OS=Homo sapiens OX=9606 GN=RPE PE=1 SV=1 9.47 3265.1 - 698610 - - - 1.7701 - 1.192 0.055 - 121.5 1 2 0 0.0014 7 0 0 0 1.13E+07 7.44E+06 - - - 0.0033 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.15852.15852.2 0.0128 12-Jul K.AFLFVNK[136.11].G sp|Q8N0X7|SPART_HUMAN 1 845.4891 1.39 12561 15852 2 845.489795 423.7518 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3265.8 - 2.58E+06 - - - 0.8516 - 1.339 0.248 - 194.4 1 2 0 0.0007 7 0 0 0 1.47E+08 1.06E+08 - - - 1.7975 0.9581 230117_WJC_METTL3_WT_vs_EV_F02.15854.15854.2 0.00463 18-Nov H.ILSPWGAEVK[136.11].A "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1106.6215 1.07 12563 15854 2 1106.621705 554.318 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3265.9 - 1.93E+06 - - - 0.1437 - 2.123 0.327 - 311.7 1 1 0 0.0002 10 0 0 0 5.78E+07 5.41E+07 - - - 3.5576 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.15860.15860.2 6.56E-05 14-Sep K.YFEYIMAK[136.11].E sp|P13674|P4HA1_HUMAN 1 1071.5191 2.74 12569 15860 2 1071.52166 536.7668 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3266.7 - 284385 - - - 2.4321 - 1.524 0.458 - 224.5 1 2 0 0.0026 8 0 0 0 4.10E+07 1.49E+07 - - - 3.6937 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.15866.15866.2 0.00011 14-Jul K.YFEYIMAK.E sp|P13674|P4HA1_HUMAN 1 1063.5049 2.74 12574 15866 2 1063.504733 532.7597 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3267.4 - 1.22E+06 - - - -0.1138 - 1.544 0.484 - 125.9 1 2 0 -0.0001 8 0 0 0 4.10E+07 1.49E+07 - - - 3.9258 0.9893 230117_WJC_METTL3_WT_vs_EV_F02.15867.15867.2 0.106 14-Aug K.GIAYIEFK.T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 939.5066 0.82 12575 15867 2 939.507921 470.7606 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3267.5 - 385508 - - - 1.4391 - 1.298 0.081 - 141.2 1 2 0 0.0014 8 0 0 0 5.03E+08 6.14E+08 - - - 0.4255 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.15872.15872.2 6.11E-05 16-Aug K.VLPVGVLYK.V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 986.6165 0.56 12578 15872 2 986.616378 494.3155 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3268.1 - 1.84E+06 - - - -0.077 - 1.569 0.462 - 171.2 1 2 0 -0.0001 9 0 0 0 9.64E+07 1.73E+08 - - - 3.7565 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.15873.15873.3 4.42E-05 16/36 R.ILIAKPIMFR.G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1200.7417 0.84 12579 15873 3 1200.740755 401.2545 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3268.2 - 1.97E+06 - - - -0.7629 - 2.421 0.295 - 258.8 1 2 0 -0.0009 10 0 0 0 3.10E+07 3.70E+07 - - - 4.4109 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.15874.15874.2 0.0067 18-Sep R.LGFVAGVINR[166.11].E "sp|Q93050|VPP1_HUMAN,tr|K7EN36|K7EN36_HUMAN,tr|K7EPG4|K7EPG4_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 5 1054.6163 2.34 12580 15874 2 1054.616426 528.3154 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 9.75 3268.3 - 798448 - - - 0.1346 - 1.833 0.33 - 218.6 1 2 0 0.0001 10 0 0 0 2.75E+07 1.17E+07 - - - 3.1697 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15877.15877.2 0.000362 18-Oct K.AFADSSYLLR[166.11].H "sp|Q9H5H4|ZN768_HUMAN,tr|H3BS42|H3BS42_HUMAN" 2 1151.585 1.05 12583 15877 2 1151.5876 576.7998 Zinc finger protein 768 OS=Homo sapiens OX=9606 GN=ZNF768 PE=1 SV=2 5.88 3268.7 - 686710 - - - 2.2195 - 1.506 0.478 - 311.9 1 2 0 0.0026 10 0 0 0 9.81E+06 9.34E+06 - - - 3.7136 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15882.15882.2 0.00285 12-Aug K.QC[160.03]FLVLR.Q "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|H7C278|H7C278_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 5 934.5059 0.53 12586 15882 2 934.507294 468.2602 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 8.25 3269.4 - 884503 - - - 1.5366 - 1.599 0.42 - 377.5 1 2 0 0.0014 7 0 0 0 2.13E+07 3.99E+07 - - - 3.6299 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.15891.15891.2 0.00211 20-Nov R.ILMVGLDAAGK.T "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|F5H1V1|F5H1V1_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|F5H6T5|F5H6T5_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|F8WDB3|F8WDB3_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 11 1086.6107 1.81 12594 15891 2 1086.612028 544.3126 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3270.3 - 2.25E+06 - - - 1.2065 - 2.286 0.431 - 345.9 1 2 0 0.0013 11 0 0 0 2.37E+08 1.31E+08 - - - 4.4607 0.9178 230117_WJC_METTL3_WT_vs_EV_F02.15893.15893.2 0.182 16-Jun K.VDIEAIFSK.Y "sp|Q86SE5|RALYL_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 4 1020.5492 5.95 12595 15893 2 1020.547177 511.2819 RNA-binding Raly-like protein OS=Homo sapiens OX=9606 GN=RALYL PE=1 SV=2 4.37 3270.5 - 709424 - - - -1.945 - 1.285 0.072 - 51.3 3 2 0 -0.002 9 0 0 0 1.26E+07 2.12E+06 - - - 0.0845 0.9916 230117_WJC_METTL3_WT_vs_EV_F02.15895.15895.2 0.841 12-Jul R.VLQLFTR[166.11].L "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 885.5312 1.16 12597 15895 2 885.530386 443.7729 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 9.72 3270.8 - 1.97E+06 - - - -0.8718 - 1.404 0.158 - 156.1 1 2 0 -0.0008 7 0 0 0 3.31E+07 2.85E+07 - - - 1.2829 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.15905.15905.2 0.0449 14-Aug K.GIAYIEFK[136.11].T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 947.5208 0.82 12604 15905 2 947.519553 474.7677 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3272 - 9.71E+06 - - - -1.2833 - 1.551 0.249 - 205.6 1 2 0 -0.0012 8 0 0 0 5.01E+08 6.14E+08 - - - 2.2034 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15908.15908.2 0.000115 16-Aug R.VFNPYTEFK.E sp|Q96C19|EFHD2_HUMAN 1 1143.5601 2.08 12606 15908 2 1143.562145 572.7873 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 5.97 3272.4 - 611736 - - - 1.8224 - 1.575 0.452 - 179.9 1 2 0 0.0021 9 0 0 0 1.89E+07 9.09E+06 - - - 3.693 0.9954 230117_WJC_METTL3_WT_vs_EV_F02.15909.15909.2 0.528 12-Jul K.ILIWSGR.F "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 843.4967 1.58 12607 15909 2 843.496045 422.7556 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 9.75 3272.4 - 1.95E+06 - - - -0.7445 - 1.427 0.209 - 183 1 2 0 -0.0006 7 0 0 0 7.26E+07 4.58E+07 - - - 1.7111 0.9848 230117_WJC_METTL3_WT_vs_EV_F02.15916.15916.2 0.134 12-Jun R.LLLAFQK.K sp|Q14781|CBX2_HUMAN 1 831.5218 1.42 12612 15916 2 831.522126 416.7682 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.75 3273.2 - 2.24E+06 - - - 0.362 - 1.278 0.069 - 91.5 1 2 0 0.0003 7 0 0 0 2.85E+07 2.01E+07 - - - 0.3278 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.15920.15920.2 0.121 12-Jul K.ILIWSGR[166.11].F "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 853.5049 1.58 12614 15920 2 853.505896 427.7597 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 9.75 3273.8 - 5.76E+06 - - - 1.1166 - 1.49 0.15 - 153.2 1 2 0 0.001 7 0 0 0 7.25E+07 4.58E+07 - - - 1.4121 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.15922.15922.2 0.00436 16-Oct R.LLLQLEATK.N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1027.6277 11.12 12616 15922 2 1027.625021 514.8211 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3274 - 3.51E+06 - - - -2.6527 - 2.064 0.342 - 263.4 1 2 0 -0.0027 9 0 0 0 6.77E+08 6.09E+07 - - - 3.6626 0.9856 230117_WJC_METTL3_WT_vs_EV_F02.15925.15925.2 0.178 18-Nov R.LAWGQPVGLR[166.11].H "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQX9|A0A0U1RQX9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 7 1105.6272 3.58 12619 15925 2 1105.62377 553.8209 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 9.75 3274.4 - 1.60E+06 - - - -3.0869 - 1.688 0.206 - 320.2 1 2 0 -0.0034 10 0 0 0 1.01E+08 2.82E+07 - - - 2.0228 0.9639 230117_WJC_METTL3_WT_vs_EV_F02.15928.15928.2 0.816 12-Jul R.TPILLIR.D "sp|P28300|LYOX_HUMAN,tr|A0A7P0SNB0|A0A7P0SNB0_HUMAN" 2 824.5484 1.91 12622 15928 2 824.547522 413.2815 Protein-lysine 6-oxidase OS=Homo sapiens OX=9606 GN=LOX PE=1 SV=2 9.41 3274.8 - 699296 - - - -1.0333 - 1.389 0.026 - 131.5 1 2 0 -0.0009 7 0 0 0 6.31E+06 3.30E+06 - - - 0.2739 0.9425 230117_WJC_METTL3_WT_vs_EV_F02.15932.15932.2 8.7 12-Jul R.LYDGLFK.V "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 10 854.4538 1.84 12624 15932 2 854.453422 428.2342 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.83 3275.2 - 2.19E+06 - - - -0.4482 - 1.12 0.043 - 99 1 2 0 -0.0004 7 0 0 0 1.66E+08 9.01E+07 - - - -0.2824 0.9938 230117_WJC_METTL3_WT_vs_EV_F02.15937.15937.2 0.557 14-Sep R.TLINELVK.G "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 7 928.5593 1.16 12627 15937 2 928.559474 465.2869 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.66 3275.9 - 729881 - - - 0.1518 - 1.348 0.149 - 232.6 1 2 0 0.0001 8 0 0 0 7.05E+07 6.09E+07 - - - 1.0421 0.9946 230117_WJC_METTL3_WT_vs_EV_F02.15940.15940.2 0.657 12-Jun K.ILIEDWK[136.11].K "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A7I2V2T6|A0A7I2V2T6_HUMAN,tr|K7EPW7|K7EPW7_HUMAN" 4 923.5208 1.28 12630 15940 2 923.521547 462.7677 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 4.37 3276.2 - 908090 - - - 0.8424 - 1.402 0.115 - 92.2 1 2 0 0.0008 7 0 0 0 2.87E+07 2.24E+07 - - - 0.9608 0.9882 230117_WJC_METTL3_WT_vs_EV_F02.15941.15941.2 1.47 12-May R.LFFVGSR.E "sp|Q9UM01|YLAT1_HUMAN,sp|Q92536|YLAT2_HUMAN,sp|Q01650|LAT1_HUMAN,tr|H0YJ95|H0YJ95_HUMAN,tr|A0A0C4DGL4|A0A0C4DGL4_HUMAN,tr|G3V4Z6|G3V4Z6_HUMAN" 6 824.4545 0.86 12631 15941 2 824.455604 413.2345 Y+L amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A7 PE=1 SV=2 9.75 3276.3 - 428004 - - - 1.3706 - 1.206 0.163 - 62.1 12 2 0 0.0011 7 0 0 0 2.28E+07 2.67E+07 - - - 0.356 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.15942.15942.2 0.0172 20-Jul K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.13 12632 15942 2 1235.760793 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3276.4 - 364102 - - - 0.5139 - 1.686 0.322 - 134.2 1 2 0 0.0006 11 0 0 0 4.19E+08 3.71E+08 - - - 2.8322 0.997 230117_WJC_METTL3_WT_vs_EV_F02.15946.15946.2 0.151 16-Sep R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 0.76 12635 15946 2 952.596914 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3276.9 - 4.01E+08 - - - 1.2555 - 1.511 0.155 - 259.7 1 2 0 0.0012 9 0 0 0 9.29E+09 1.22E+10 - - - 1.3796 1 230117_WJC_METTL3_WT_vs_EV_F02.15948.15948.2 4.13E-05 16-Oct R.MNVLADALK[136.11].S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 981.5409 1.36 12636 15948 2 981.538212 491.7777 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3277.1 - 2.22E+06 - - - -2.6907 - 2.147 0.453 - 419.6 1 2 0 -0.0026 9 0 0 0 5.52E+08 4.04E+08 - - - 4.5965 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.15949.15949.2 0.0891 18-Oct K.ILPEEITNLR.N sp|Q9H9A6|LRC40_HUMAN 1 1196.6765 1 12637 15949 2 1196.67634 599.3455 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3277.3 - 1.18E+06 - - - -0.1237 - 1.675 0.338 - 382.5 1 2 0 -0.0001 10 0 0 0 4.09E+07 4.08E+07 - - - 2.9772 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.15950.15950.2 0.221 16-Aug R.LLLQLEATK[136.11].N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1035.6419 10.77 12638 15950 2 1035.64232 518.8282 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3277.3 - 3.55E+06 - - - 0.3602 - 1.735 0.372 - 157.5 1 2 0 0.0004 9 0 0 0 6.55E+08 6.08E+07 - - - 3.3826 0.9933 230117_WJC_METTL3_WT_vs_EV_F02.15951.15951.2 0.534 20-Sep K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.13 12639 15951 2 1245.772743 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3277.4 - 1.91E+06 - - - 3.4637 - 1.41 0.2 - 105.1 1 2 0 0.0043 11 0 0 0 4.19E+08 3.71E+08 - - - 1.4463 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.15960.15960.2 0.0234 12-Aug R.LYDGLFK[136.11].V "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 10 862.468 1.84 12646 15960 2 862.468956 432.2413 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.83 3278.4 - 2.97E+06 - - - 1.1026 - 1.612 0.32 - 183.9 1 2 0 0.001 7 0 0 0 1.62E+08 8.76E+07 - - - 2.9171 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.15967.15967.2 5.22E-05 16-Sep R.MNVLADALK.S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 973.5267 1.36 12652 15967 2 973.527247 487.7706 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3279.3 - 4.93E+06 - - - 0.6102 - 2.124 0.422 - 341.2 1 2 0 0.0006 9 0 0 0 5.52E+08 4.04E+08 - - - 4.337 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.15970.15970.2 0.000745 16-Jul K.VLPVGVLYK[136.11].V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 994.6307 0.56 12654 15970 2 994.631082 498.3226 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3279.6 - 4.98E+06 - - - 0.4303 - 1.502 0.431 - 145.4 1 2 0 0.0004 9 0 0 0 9.64E+07 1.73E+08 - - - 3.4011 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.15971.15971.2 0.47 16-Sep K.AGIPVYAWK[136.11].G sp|P23526|SAHH_HUMAN 1 1011.5633 -1 12655 15971 2 1011.564427 506.7889 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 8.63 3279.7 - 1.22E+06 - - - 1.1121 - 1.481 0.19 - 145.6 1 2 0 0.0011 9 0 0 0 0.00E+00 0.00E+00 - - - 1.5801 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15972.15972.2 0.000398 18-Sep K.ILPEEITNLR[166.11].N sp|Q9H9A6|LRC40_HUMAN 1 1206.6848 2.19 12656 15972 2 1206.687446 604.3497 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3279.8 - 860782 - - - 2.2276 - 1.763 0.44 - 332.3 1 2 0 0.0027 10 0 0 0 3.16E+07 1.44E+07 - - - 3.8727 1 230117_WJC_METTL3_WT_vs_EV_F02.15974.15974.2 6.18E-06 14/20 R.LVDAVLGAEIR[166.11].N "sp|Q9UBN7|HDAC6_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8Y758|A0A2R8Y758_HUMAN,tr|A0A2R8Y559|A0A2R8Y559_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 5 1164.6742 0.85 12658 15974 2 1164.676096 583.3444 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.37 3280.1 - 538172 - - - 1.6339 - 2.552 0.478 - 441.8 1 2 0 0.0019 11 0 0 0 5.02E+07 5.89E+07 - - - 5.1054 0.9942 230117_WJC_METTL3_WT_vs_EV_F02.15979.15979.2 0.861 12-May R.LFFVGSR[166.11].E "sp|Q9UM01|YLAT1_HUMAN,sp|Q92536|YLAT2_HUMAN,sp|Q01650|LAT1_HUMAN,tr|H0YJ95|H0YJ95_HUMAN,tr|A0A0C4DGL4|A0A0C4DGL4_HUMAN,tr|G3V4Z6|G3V4Z6_HUMAN" 6 834.4627 0.85 12660 15979 2 834.462648 418.2386 Y+L amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A7 PE=1 SV=2 9.75 3280.8 - 1.19E+06 - - - -0.115 - 1.205 0.213 - 100 1 2 0 -0.0001 7 0 0 0 2.28E+07 2.68E+07 - - - 1.2051 0.9752 230117_WJC_METTL3_WT_vs_EV_F02.15980.15980.2 0.00361 18-Nov R.LAWGQPVGLR.H "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQX9|A0A0U1RQX9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 7 1095.6189 3.68 12661 15980 2 1095.623946 548.8167 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 9.75 3280.9 - 722470 - - - 4.5938 - 1.89 0.026 - 290.4 1 2 0 0.005 10 0 0 0 9.52E+07 2.59E+07 - - - 1.0083 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.15981.15981.2 0.142 14-Sep K.AVWLPAVK.A "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 882.5327 1.34 12662 15981 2 882.534984 442.2736 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.8 3281 - 836865 - - - 2.5608 - 1.407 0.179 - 274.3 1 2 0 0.0023 8 0 0 0 3.27E+07 2.44E+07 - - - 1.3922 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.15983.15983.2 0.00272 18-Oct R.VPFLVAETPR.A sp|Q13131|AAPK1_HUMAN 1 1127.6339 7.19 12664 15983 2 1127.635815 564.8242 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4 5.97 3281.3 - 385806 - - - 1.7027 - 1.808 0.384 - 292.6 1 2 0 0.0019 10 0 0 0 1.19E+07 1.65E+06 - - - 3.5297 0.9898 230117_WJC_METTL3_WT_vs_EV_F02.15986.15986.2 0.873 14-Jul R.TLINELVK[136.11].G "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 7 936.5735 1.2 12665 15986 2 936.575048 469.294 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.66 3281.6 - 1.85E+06 - - - 1.6176 - 1.308 0.084 - 147.4 1 2 0 0.0015 8 0 0 0 7.41E+07 6.16E+07 - - - 0.4707 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.15994.15994.2 0.0263 14-Jul R.LLGWIQNK[136.11].L "sp|O75369|FLNB_HUMAN,sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN,tr|F8WE98|F8WE98_HUMAN" 11 978.5742 2.92 12671 15994 2 978.575517 490.2944 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 8.75 3282.5 - 520921 - - - 1.3438 - 1.311 0.32 - 108.8 1 2 0 0.0013 8 0 0 0 6.75E+07 2.31E+07 - - - 2.2208 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.15998.15998.2 0.00711 14-Jul K.LLFVPC[160.03]SR[166.11].V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 1000.5403 0.9 12673 15998 2 1000.539759 501.2774 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.25 3283 - 1.46E+06 - - - -0.5827 - 1.643 0.275 - 148.9 1 2 0 -0.0006 8 0 0 0 3.89E+07 4.34E+07 - - - 2.5695 0.9898 230117_WJC_METTL3_WT_vs_EV_F02.16000.16000.2 0.108 14-Jul K.LLFVPC[160.03]SR.V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 990.5321 0.9 12675 16000 2 990.535265 496.2733 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.25 3283.2 - 1.47E+06 - - - 3.2235 - 1.528 0.091 - 139.4 1 2 0 0.0032 8 0 0 0 3.92E+07 4.34E+07 - - - 0.9908 1 230117_WJC_METTL3_WT_vs_EV_F02.16003.16003.2 6.22E-06 16-Sep K.VIVPNMEFR.A sp|P55060|XPO2_HUMAN 1 1103.5798 1.27 12676 16003 2 1103.580138 552.7972 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.97 3283.6 - 1.97E+06 - - - 0.3507 - 1.915 0.599 - 273.6 1 2 0 0.0004 9 0 0 0 1.23E+08 9.63E+07 - - - 5.3448 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.16004.16004.2 0.012 18-Sep R.TVPLLLAESK[136.11].F sp|Q709C8|VP13C_HUMAN 1 1077.6525 1.08 12677 16004 2 1077.65426 539.8335 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 5.66 3283.7 - 327578 - - - 1.623 - 1.521 0.249 - 207.2 1 2 0 0.0017 10 0 0 0 8.78E+06 8.11E+06 - - - 2.0501 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.16007.16007.2 0.000126 18-Oct R.GYFEYIEENK.Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1290.5768 1.24 12680 16007 2 1290.578156 646.2957 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3284 - 365784 - - - 1.0251 - 1.854 0.505 - 318.2 1 2 0 0.0013 10 0 0 0 9.79E+06 7.92E+06 - - - 4.4937 1 230117_WJC_METTL3_WT_vs_EV_F02.16015.16015.2 7.68E-06 18-Dec K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 7.7 12686 16015 2 1149.58413 575.7982 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3285 - 498668 - - - 1.9755 - 2.263 0.481 - 561.4 1 2 0 0.0023 10 0 0 0 9.14E+08 1.19E+08 - - - 4.8726 0.9712 230117_WJC_METTL3_WT_vs_EV_F02.16018.16018.2 0.0424 16-May R.EPLSLINVR[166.11].K sp|Q96HS1|PGAM5_HUMAN 1 1049.6109 0.02 12687 16018 2 1049.60963 525.8127 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 6.1 3285.5 - 403038 - - - -1.1766 - 1.238 0.168 - 50.9 8 2 0 -0.0012 9 0 0 0 2.84E+05 1.58E+07 - - - 0.4957 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.16020.16020.2 0.000279 14-Oct R.TAYLLYYR.R sp|Q14694|UBP10_HUMAN 1 1061.5546 0.92 12689 16020 2 1061.556534 531.7846 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.16 3285.7 - 1.21E+06 - - - 1.8388 - 1.65 0.392 - 470.1 1 2 0 0.002 8 0 0 0 3.32E+07 3.60E+07 - - - 3.446 0.9969 230117_WJC_METTL3_WT_vs_EV_F02.16022.16022.2 0.0328 24-Jul K.LGPGAGAGFGVLR.R "sp|Q9BUL5|PHF23_HUMAN,tr|I3L1N0|I3L1N0_HUMAN,tr|I3L410|I3L410_HUMAN,tr|I3L4Q4|I3L4Q4_HUMAN" 4 1170.6509 4.89 12691 16022 2 1170.653278 586.3327 PHD finger protein 23 OS=Homo sapiens OX=9606 GN=PHF23 PE=1 SV=1 9.75 3286 - 339848 - - - 1.9955 - 1.469 0.19 - 86.6 1 2 0 0.0023 13 0 0 0 8.00E+06 1.64E+06 - - - 1.4306 1 230117_WJC_METTL3_WT_vs_EV_F02.16028.16028.2 0.000965 18-Dec K.FAEAFEAIPR[166.11].A sp|P50990|TCPQ_HUMAN 1 1159.5901 7.6 12694 16028 2 1159.593824 580.8023 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3286.7 - 304999 - - - 3.1865 - 2.39 0.511 - 507 1 2 0 0.0037 10 0 0 0 9.16E+08 1.21E+08 - - - 5.2461 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.16032.16032.2 0.0332 14-Jul K.ELPTVVFR[166.11].A sp|Q9BVP2|GNL3_HUMAN 1 969.5523 0.9 12696 16032 2 969.555205 485.7834 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 6.1 3287.2 - 1.36E+07 - - - 3.0096 - 1.43 0.329 - 109.1 1 2 0 0.0029 8 0 0 0 1.12E+08 1.24E+08 - - - 2.5488 0.9935 230117_WJC_METTL3_WT_vs_EV_F02.16044.16044.2 1.77 12-Jul R.MIEFVVR[166.11].E "sp|O15042|SR140_HUMAN,tr|E7ET15|E7ET15_HUMAN" 2 902.4923 1.32 12706 16044 2 902.494206 452.2534 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 5.75 3288.6 - 473324 - - - 2.0798 - 1.305 0.134 - 177.5 1 2 0 0.0019 7 0 0 0 3.27E+07 2.47E+07 - - - 0.8736 0.9436 230117_WJC_METTL3_WT_vs_EV_F02.16050.16050.2 1.58 12-May R.QLSVLFR.K sp|Q96HR3|MED30_HUMAN 1 861.5072 2.59 12710 16050 2 861.509514 431.7609 Mediator of RNA polymerase II transcription subunit 30 OS=Homo sapiens OX=9606 GN=MED30 PE=1 SV=1 9.75 3289.4 - 556177 - - - 2.6419 - 1.111 0.045 - 110.2 2 2 0 0.0023 7 0 0 0 2.09E+07 8.07E+06 - - - -0.4283 0.8958 230117_WJC_METTL3_WT_vs_EV_F02.16051.16051.2 3.23 14-Apr R.ILVIGLSR[166.11].E sp|Q8N201|INT1_HUMAN 1 879.5781 1.23 12711 16051 2 879.579853 440.7963 Integrator complex subunit 1 OS=Homo sapiens OX=9606 GN=INTS1 PE=1 SV=2 9.75 3289.6 - 279672 - - - 1.9839 - 0.965 0.085 - 29 20 2 0 0.0017 8 0 0 0 8.63E+06 7.01E+06 - - - -1.0204 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.16052.16052.2 0.0284 14-Jul K.ELPTVVFR.A sp|Q9BVP2|GNL3_HUMAN 1 959.544 0.9 12712 16052 2 959.545441 480.7793 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 6.1 3289.6 - 3.45E+06 - - - 1.484 - 1.335 0.364 - 188.7 1 2 0 0.0014 8 0 0 0 1.12E+08 1.24E+08 - - - 2.6005 0.9893 230117_WJC_METTL3_WT_vs_EV_F02.16053.16053.2 0.236 14-Sep R.TAYLLYYR[166.11].R sp|Q14694|UBP10_HUMAN 1 1071.5629 0.92 12713 16053 2 1071.565772 536.7887 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.16 3289.7 - 650723 - - - 2.725 - 1.256 0.137 - 292.3 1 2 0 0.0029 8 0 0 0 3.32E+07 3.61E+07 - - - 0.7394 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16054.16054.2 4.47E-05 14-Aug K.FC[160.03]ELLIGR.G "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1006.527 999 12714 16054 2 1006.529082 504.2708 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.99 3289.7 - 630643 - - - 2.0814 - 1.757 0.45 - 215 1 2 0 0.0021 8 0 0 0 1.95E+08 0.00E+00 - - - 4.0639 0.998 230117_WJC_METTL3_WT_vs_EV_F02.16062.16062.2 0.339 14-Jul K.LFIGNLPR[166.11].E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 938.5577 2.15 12720 16062 2 938.559572 470.2861 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3290.6 - 1.12E+06 - - - 1.9871 - 1.388 0.242 - 133.6 1 2 0 0.0019 8 0 0 0 3.24E+09 1.50E+09 - - - 1.8166 0.953 230117_WJC_METTL3_WT_vs_EV_F02.16072.16072.2 2.98 12-Jun K.VWEGFIK.C "sp|Q92797|SYMPK_HUMAN,tr|M0R033|M0R033_HUMAN" 2 877.4698 1.73 12726 16072 2 877.471534 439.7422 Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2 5.97 3291.8 - 480948 - - - 1.9875 - 0.933 0.093 - 78.2 1 2 0 0.0017 7 0 0 0 1.05E+07 6.04E+06 - - - -0.4924 0.9833 230117_WJC_METTL3_WT_vs_EV_F02.16076.16076.2 0.939 12-Jun K.VFGIQLK.E "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN" 3 803.4905 3.34 12728 16076 2 803.492286 402.7525 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 8.72 3292.3 - 1.06E+06 - - - 2.1917 - 1.061 0.137 - 101.8 1 2 0 0.0018 7 0 0 0 6.92E+07 2.07E+07 - - - 0.2399 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.16079.16079.2 0.00161 16-Oct K.VIVPNMEFR[166.11].A sp|P55060|XPO2_HUMAN 1 1113.588 1.27 12729 16079 2 1113.58897 557.8013 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.97 3292.7 - 1.67E+06 - - - 0.8522 - 1.941 0.42 - 417.5 1 2 0 0.0009 9 0 0 0 1.22E+08 9.60E+07 - - - 4.0615 0.9957 230117_WJC_METTL3_WT_vs_EV_F02.16080.16080.2 0.165 12-Jul K.MIFVGIK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 806.4724 2 12730 16080 2 806.472896 404.2435 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 8.5 3292.9 - 1.22E+06 - - - 0.5753 - 1.409 0.145 - 170.8 1 2 0 0.0005 7 0 0 0 3.89E+07 1.94E+07 - - - 1.1983 0.9963 230117_WJC_METTL3_WT_vs_EV_F02.16082.16082.2 0.282 14-Aug R.VLSIWEER[166.11].S "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1040.553 5.61 12732 16082 2 1040.555451 521.2838 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.53 3293 - 2.13E+06 - - - 2.3411 - 1.468 0.163 - 205.1 1 2 0 0.0024 8 0 0 0 2.27E+08 4.04E+07 - - - 1.402 0.9841 230117_WJC_METTL3_WT_vs_EV_F02.16083.16083.2 0.00244 20-Nov K.LLLIGDSGVGK.T "sp|P61006|RAB8A_HUMAN,sp|P51153|RAB13_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P59190|RAB15_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YL94|H0YL94_HUMAN,tr|A0A2R8YDI9|A0A2R8YDI9_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|G3V196|G3V196_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H0YLJ8|H0YLJ8_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN,tr|F5H157|F5H157_HUMAN" 19 1070.6336 1.44 12733 16083 2 1070.642527 536.3241 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.84 3293.1 - 900742 - - - 8.3754 - 2.193 0.371 - 350 1 2 0 0.009 11 0 0 0 3.71E+08 2.57E+08 - - - 3.9027 0.9822 230117_WJC_METTL3_WT_vs_EV_F02.16090.16090.2 13.1 12-Jul R.LILQIGR[166.11].G "sp|Q9NP73|ALG13_HUMAN,tr|A0A096LNJ4|A0A096LNJ4_HUMAN,tr|A0A087WX43|A0A087WX43_HUMAN,tr|A0A087WTT9|A0A087WTT9_HUMAN,tr|D6RE84|D6RE84_HUMAN,tr|A0A096LP10|A0A096LP10_HUMAN,tr|A0A096LNL2|A0A096LNL2_HUMAN,tr|A0A1B0GVW6|A0A1B0GVW6_HUMAN" 8 821.5362 1.15 12736 16090 2 821.537683 411.7754 Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 OS=Homo sapiens OX=9606 GN=ALG13 PE=1 SV=2 9.75 3294 - 1.34E+07 - - - 1.7528 - 1.523 0 - 180.4 4 2 0 0.0014 7 0 0 0 4.76E+08 4.14E+08 - - - 0.1046 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.16091.16091.2 0.122 14-Jul K.ELPTVVFR.A sp|Q9BVP2|GNL3_HUMAN 1 959.544 0.9 12737 16091 2 959.546514 480.7793 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 6.1 3294 - 2.09E+06 - - - 2.6023 - 1.378 0.337 - 149 1 2 0 0.0025 8 0 0 0 1.12E+08 1.24E+08 - - - 2.4963 0.997 230117_WJC_METTL3_WT_vs_EV_F02.16098.16098.2 0.179 12-Jul K.LFQLYPR[166.11].N sp|Q8IXM3|RM41_HUMAN 1 945.5312 1.01 12742 16098 2 945.532268 473.7729 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 8.75 3294.9 - 878958 - - - 1.1739 - 1.574 0.122 - 178.3 1 2 0 0.0011 7 0 0 0 9.92E+07 9.82E+07 - - - 1.3791 0.9696 230117_WJC_METTL3_WT_vs_EV_F02.16099.16099.2 0.198 14-Aug R.LEEIPLIK.S sp|Q14152|EIF3A_HUMAN 1 953.5797 0.94 12743 16099 2 953.576656 477.7971 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 3294.9 - 1.11E+06 - - - -3.2278 - 1.474 0.165 - 140.6 1 2 0 -0.0031 8 0 0 0 7.22E+07 7.65E+07 - - - 1.4289 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.16105.16105.2 0.15 16-Aug K.LTLLQVASR.Q sp|O95239|KIF4A_HUMAN 1 999.6077 2.08 12746 16105 2 999.609044 500.8111 Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3 9.75 3295.7 - 1.70E+06 - - - 1.3645 - 1.745 0.225 - 156.5 1 2 0 0.0014 9 0 0 0 3.14E+07 1.51E+07 - - - 2.3131 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.16106.16106.2 0.000672 16-Sep K.VYEAVELLK.S sp|Q8TEQ6|GEMI5_HUMAN 1 1062.5961 0.36 12747 16106 2 1062.597617 532.3053 Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3 4.53 3295.8 - 933265 - - - 1.4163 - 1.412 0.398 - 220.9 1 2 0 0.0015 9 0 0 0 2.11E+07 5.94E+07 - - - 2.9783 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.16107.16107.2 0.0706 14-Sep R.LISLPLSR.L "sp|Q9NRG0|CHRC1_HUMAN,tr|E5RGS9|E5RGS9_HUMAN" 2 897.5648 1.83 12748 16107 2 897.565572 449.7897 Chromatin accessibility complex protein 1 OS=Homo sapiens OX=9606 GN=CHRAC1 PE=1 SV=1 9.75 3295.8 - 941626 - - - 0.9125 - 1.686 0.211 - 209 1 2 0 0.0008 8 0 0 0 7.36E+07 4.02E+07 - - - 2.1746 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.16108.16108.3 0.0805 Dec-36 K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 13.38 12749 16108 3 1149.582453 384.2012 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3296 - 624160 - - - 0.5167 - 1.687 0.331 - 241.6 1 2 0 0.0006 10 0 0 0 1.49E+07 1.11E+06 - - - 3.7574 0.9551 230117_WJC_METTL3_WT_vs_EV_F02.16113.16113.2 1.84 14-May R.LISLPLSR[166.11].L "sp|Q9NRG0|CHRC1_HUMAN,tr|E5RGS9|E5RGS9_HUMAN" 2 907.573 1.83 12752 16113 2 907.574832 454.7938 Chromatin accessibility complex protein 1 OS=Homo sapiens OX=9606 GN=CHRAC1 PE=1 SV=1 9.75 3296.6 - 1.65E+06 - - - 1.9932 - 1.064 0.042 - 64.2 1 2 0 0.0018 8 0 0 0 7.36E+07 4.02E+07 - - - -0.4623 0.9964 230117_WJC_METTL3_WT_vs_EV_F02.16115.16115.2 0.383 12-Aug K.IIAALFK.A "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 774.5004 1.79 12754 16115 2 774.50046 388.2575 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3296.8 - 567008 - - - 0.1278 - 1.466 0.169 - 145.5 1 2 0 0.0001 7 0 0 0 3.03E+07 1.69E+07 - - - 1.5013 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.16119.16119.2 0.0115 12-Jul K.FGDFVLK[136.11].S "sp|P11172|UMPS_HUMAN,tr|F2Z303|F2Z303_HUMAN,tr|F2Z3P2|F2Z3P2_HUMAN,tr|F8WDG4|F8WDG4_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 5 832.4574 2.36 12756 16119 2 832.458113 417.236 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 5.84 3297.3 - 885418 - - - 0.8084 - 1.606 0.328 - 122.1 1 2 0 0.0007 7 0 0 0 7.00E+07 2.97E+07 - - - 2.9645 0.9899 230117_WJC_METTL3_WT_vs_EV_F02.16120.16120.2 4.55 12-May K.IIAALFK[136.11].A "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 782.5146 1.76 12757 16120 2 782.51584 392.2646 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3297.5 - 413268 - - - 1.6345 - 1.249 0.099 - 59.4 1 2 0 0.0013 7 0 0 0 2.99E+07 1.69E+07 - - - 0.4763 0.9838 230117_WJC_METTL3_WT_vs_EV_F02.16125.16125.2 2.5 14-Aug K.GGLGLILK.R "sp|O75832|PSD10_HUMAN,tr|B1AJY5|B1AJY5_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 3 769.5062 1.59 12762 16125 2 769.508812 385.7604 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 8.75 3298 - 421550 - - - 3.4269 - 1.263 0.135 - 145.2 1 2 0 0.0026 8 0 0 0 7.70E+07 4.83E+07 - - - 0.7415 0.998 230117_WJC_METTL3_WT_vs_EV_F02.16136.16136.2 0.0273 14-Jul R.GFVLYPVK.Y sp|P62487|RPB7_HUMAN 1 921.5324 0.01 12769 16136 2 921.53401 461.7735 DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1 8.59 3299.4 - 394138 - - - 1.7579 - 1.131 0.317 - 126.6 1 2 0 0.0016 8 0 0 0 2.07E+07 1.58E+09 - - - 1.7531 0.9393 230117_WJC_METTL3_WT_vs_EV_F02.16138.16138.2 0.0174 14-Oct R.PLELSDFR.M "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 975.5025 1.6 12771 16138 2 975.503819 488.7585 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.37 3299.6 - 488212 - - - 1.305 - 1.799 0.243 - 373.4 1 1 0 0.0013 8 0 0 0 5.07E+07 3.18E+07 - - - 2.6065 0.8586 230117_WJC_METTL3_WT_vs_EV_F02.16139.16139.2 1.25 14-Sep R.PLELSDFR[166.11].M "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 985.5108 1.68 12772 16139 2 985.512452 493.7627 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.37 3299.8 - 305977 - - - 1.6601 - 1.699 0.145 - 237.2 1 1 0 0.0016 8 0 0 0 5.02E+07 2.99E+07 - - - 1.71 0.9858 230117_WJC_METTL3_WT_vs_EV_F02.16146.16146.2 0.391 16-May R.IVATLPYIK[136.11].Q "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1024.6412 1.24 12777 16146 2 1024.642747 513.3279 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 8.59 3300.6 - 459004 - - - 1.4922 - 1.126 0.157 - 39.5 5 2 0 0.0015 9 0 0 0 1.22E+08 9.84E+07 - - - 0.2312 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.16147.16147.2 0.0853 18-Aug K.AMTILLEEAK.A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1117.6053 2.06 12778 16147 2 1117.60895 559.8099 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3300.7 - 216002 - - - 3.2686 - 2.015 0.29 - 179.1 1 2 0 0.0037 10 0 0 0 4.52E+07 2.19E+07 - - - 3.1374 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.16148.16148.2 0.000817 18-Aug K.ILVEEMAPLK.G "sp|Q16670|ZSC26_HUMAN,tr|A0A087WXM4|A0A087WXM4_HUMAN,tr|A0A024RCN4|A0A024RCN4_HUMAN,tr|A0A087X2F1|A0A087X2F1_HUMAN" 4 1141.6417 999 12779 16148 2 1141.645534 571.8281 Zinc finger and SCAN domain-containing protein 26 OS=Homo sapiens OX=9606 GN=ZSCAN26 PE=1 SV=2 4.53 3300.9 - 194561 - - - 3.3741 - 1.646 0.358 - 77.5 1 2 0 0.0039 10 0 0 0 4.05E+06 0.00E+00 - - - 3.075 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.16152.16152.2 0.115 18-Sep K.AMTILLEEAK[136.11].A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1125.6195 2.06 12781 16152 2 1125.620787 563.817 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3301.4 - 292175 - - - 1.146 - 1.726 0.273 - 221.9 1 2 0 0.0013 10 0 0 0 4.53E+07 2.19E+07 - - - 2.5805 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.16155.16155.2 0.148 12-Jul R.LSAIFLR.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 818.5014 1.55 12784 16155 2 818.502119 410.258 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3301.6 - 821506 - - - 0.8491 - 1.699 0.084 - 161.7 1 2 0 0.0007 7 0 0 0 4.99E+07 3.22E+07 - - - 1.3407 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.16156.16156.2 0.0102 18-Aug K.GFLAGYVVAK.L sp|L0R6Q1|S35U4_HUMAN 1 1023.5753 3.22 12785 16156 2 1023.575676 512.7949 SLC35A4 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=SLC35A4 PE=3 SV=1 8.59 3301.7 - 247180 - - - 0.3507 - 1.424 0.391 - 106 1 2 0 0.0004 10 0 0 0 1.98E+07 6.16E+06 - - - 2.9155 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.16165.16165.2 3.01 12-Aug R.LSAIFLR[166.11].L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 828.5097 1.59 12790 16165 2 828.510157 415.2621 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3302.8 - 799973 - - - 0.5588 - 1.732 0.136 - 170.7 1 2 0 0.0005 7 0 0 0 4.96E+07 3.11E+07 - - - 1.7858 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.16171.16171.2 0.167 18-Aug K.LLADELISPK[136.11].D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1105.6474 1.08 12794 16171 2 1105.64807 553.831 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3303.5 - 539650 - - - 0.5825 - 1.789 0.312 - 121.7 1 2 0 0.0006 10 0 0 0 6.96E+07 6.46E+07 - - - 2.9688 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16173.16173.2 0.000367 16-Sep K.YEDGIALLR[166.11].N "sp|Q9UJX3|APC7_HUMAN,tr|H0YIW2|H0YIW2_HUMAN" 2 1058.5636 0.98 12796 16173 2 1058.564882 530.2891 Anaphase-promoting complex subunit 7 OS=Homo sapiens OX=9606 GN=ANAPC7 PE=1 SV=4 4.37 3303.7 - 354870 - - - 1.23 - 1.653 0.415 - 175.1 1 2 0 0.0013 9 0 0 0 1.37E+07 1.40E+07 - - - 3.5598 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.16174.16174.2 0.0237 12-May R.EYFYGFR.G "sp|Q92989|CLP1_HUMAN,tr|E9PL17|E9PL17_HUMAN" 2 980.4392 3.91 12797 16174 2 980.440767 491.2269 Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1 6.1 3303.8 - 279257 - - - 1.5799 - 1.095 0.245 - 71 1 2 0 0.0015 7 0 0 0 5.28E+06 1.35E+06 - - - 1.1376 0.9817 230117_WJC_METTL3_WT_vs_EV_F02.16178.16178.2 4.59 12-Jun R.NLVLLVR[166.11].E sp|Q9H2W6|RM46_HUMAN 1 835.5519 1.04 12799 16178 2 835.552698 418.7832 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 9.75 3304.3 - 1.12E+06 - - - 0.9634 - 1.382 0.002 - 158.4 1 2 0 0.0008 7 0 0 0 4.91E+07 4.74E+07 - - - 0.0806 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.16179.16179.2 0.0722 16-Nov K.VVDVLDSIK[136.11].T sp|P00918|CAH2_HUMAN 1 994.579 0.84 12800 16179 2 994.579829 498.2968 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.21 3304.4 - 732372 - - - 0.8215 - 2.052 0.215 - 349.4 1 2 0 0.0008 9 0 0 0 2.30E+07 2.74E+07 - - - 2.7083 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.16186.16186.2 1.47 12-Jul K.ILPDILK.K "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 810.5215 1.74 12805 16186 2 810.522204 406.268 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 3305.1 - 937545 - - - 0.8797 - 1.557 0.159 - 131.9 1 2 0 0.0007 7 0 0 0 1.01E+08 5.80E+07 - - - 1.6181 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16187.16187.2 0.00595 16-Sep R.FDDPLLGPR[166.11].R "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 8 1038.5374 0.92 12806 16187 2 1038.537817 520.276 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.21 3305.2 - 294551 - - - 0.4352 - 1.73 0.435 - 220.5 1 2 0 0.0005 9 0 0 0 7.18E+07 7.83E+07 - - - 3.8395 1 230117_WJC_METTL3_WT_vs_EV_F02.16193.16193.2 1.61E-05 13/18 K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 374.47 12810 16193 2 1146.630622 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3305.9 - 1.27E+06 - - - 1.8724 - 2.32 0.532 - 496.1 1 2 0 0.0021 10 0 0 0 6.93E+09 1.85E+07 - - - 5.3187 0.9954 230117_WJC_METTL3_WT_vs_EV_F02.16196.16196.2 15.5 12-Aug R.NLVLLVR.E sp|Q9H2W6|RM46_HUMAN 1 825.5436 1.04 12813 16196 2 825.544725 413.7791 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 9.75 3306.1 - 742304 - - - 1.3349 - 1.489 0.1 - 272.2 1 2 0 0.0011 7 0 0 0 4.91E+07 4.74E+07 - - - 1.0407 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.16198.16198.2 0.0203 20-Sep K.C[160.03]ILVASPGFVR.E sp|Q9BRX2|PELO_HUMAN 1 1217.6591 4.59 12815 16198 2 1217.662564 609.8368 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 8.25 3306.3 - 427533 - - - 2.8744 - 1.773 0.171 - 210.8 1 2 0 0.0035 11 0 0 0 1.64E+07 3.57E+06 - - - 1.8521 0.9946 230117_WJC_METTL3_WT_vs_EV_F02.16200.16200.2 0.319 14-May K.LFIGNLPR.E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 928.5494 2.15 12816 16200 2 928.550984 465.282 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3306.5 - 7.54E+07 - - - 1.666 - 1.099 0.218 - 107.2 1 2 0 0.0015 8 0 0 0 3.24E+09 1.50E+09 - - - 0.9354 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.16201.16201.2 0.0373 20-Oct K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.17 12817 16201 2 1235.762478 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3306.6 - 2.41E+06 - - - 1.8774 - 1.945 0.304 - 327.1 1 2 0 0.0023 11 0 0 0 6.11E+07 5.23E+07 - - - 3.0853 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.16203.16203.2 0.0717 20-Sep K.C[160.03]ILVASPGFVR[166.11].E sp|Q9BRX2|PELO_HUMAN 1 1227.6673 4.59 12819 16203 2 1227.667807 614.8409 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 8.25 3306.8 - 274620 - - - 0.3853 - 1.78 0.217 - 236.5 1 2 0 0.0005 11 0 0 0 1.64E+07 3.57E+06 - - - 2.2035 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.16208.16208.2 0.0242 16-Sep K.VVDVLDSIK.T sp|P00918|CAH2_HUMAN 1 986.5648 0.84 12822 16208 2 986.565555 494.2897 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.21 3307.4 - 796244 - - - 0.7531 - 1.453 0.3 - 168.7 1 2 0 0.0007 9 0 0 0 2.30E+07 2.72E+07 - - - 2.3375 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16210.16210.2 0.0682 20-Sep K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.17 12823 16210 2 1245.76953 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3307.6 - 1.64E+06 - - - 0.8846 - 1.843 0.378 - 225.9 1 2 0 0.0011 11 0 0 0 6.11E+07 5.23E+07 - - - 3.4865 1 230117_WJC_METTL3_WT_vs_EV_F02.16215.16215.2 6.95E-05 20-Oct K.NSLESYAFNMK.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1302.5914 154.74 12827 16215 2 1302.594164 652.303 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6 3308.1 - 750809 - - - 2.0928 - 2.224 0.51 - 402 1 2 0 0.0027 11 0 0 0 1.33E+07 8.63E+04 - - - 4.9693 1 230117_WJC_METTL3_WT_vs_EV_F02.16216.16216.2 0.00599 20-Oct K.LLDSITVPVAR[166.11].A sp|O00203|AP3B1_HUMAN 1 1192.7055 1.37 12828 16216 2 1192.710332 597.36 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3308.2 - 393586 - - - 4.0572 - 2.122 0.492 - 299.4 1 2 0 0.0048 11 0 0 0 2.78E+07 2.03E+07 - - - 4.7087 0.996 230117_WJC_METTL3_WT_vs_EV_F02.16220.16220.2 0.0752 16-Jul R.IVLNGIDLK.A sp|O15294|OGT1_HUMAN 1 983.6015 2.18 12830 16220 2 983.602989 492.808 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 5.84 3308.8 - 837326 - - - 1.4813 - 1.223 0.206 - 83.6 1 2 0 0.0015 9 0 0 0 2.87E+07 1.32E+07 - - - 1.1444 0.9965 230117_WJC_METTL3_WT_vs_EV_F02.16221.16221.2 0.0063 16-Jun R.IVLNGIDLK[136.11].A sp|O15294|OGT1_HUMAN 1 991.6157 2.18 12831 16221 2 991.616349 496.8151 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 5.84 3308.8 - 302022 - - - 0.6222 - 1.489 0.156 - 71.5 1 2 0 0.0006 9 0 0 0 2.87E+07 1.32E+07 - - - 1.3448 0.996 230117_WJC_METTL3_WT_vs_EV_F02.16222.16222.2 0.563 12-Jul K.ILPDILK[136.11].K "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 818.5357 2.38 12832 16222 2 818.53568 410.2751 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 3308.9 - 1.04E+06 - - - -0.0134 - 1.441 0.172 - 116.2 1 2 0 0 7 0 0 0 9.91E+07 4.16E+07 - - - 1.469 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16224.16224.2 0.00549 16-Oct R.WLNYGGVIK.N "sp|P49642|PRI1_HUMAN,tr|F8VSB2|F8VSB2_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN" 3 1048.5706 0.66 12834 16224 2 1048.57154 525.2926 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 8.59 3309.1 - 369265 - - - 0.9289 - 1.904 0.382 - 266 1 2 0 0.001 9 0 0 0 5.52E+06 8.33E+06 - - - 3.7251 0.9941 230117_WJC_METTL3_WT_vs_EV_F02.16225.16225.2 0.267 16-Aug R.LLGLEEQLR[166.11].A "sp|P28290|ITPI2_HUMAN,tr|E9PHV5|E9PHV5_HUMAN,tr|E7EUL7|E7EUL7_HUMAN" 3 1079.6214 3.29 12835 16225 2 1079.621192 540.818 Protein ITPRID2 OS=Homo sapiens OX=9606 GN=ITPRID2 PE=1 SV=3 4.53 3309.2 - 191786 - - - -0.2195 - 1.536 0.129 - 141.1 1 2 0 -0.0002 9 0 0 0 1.10E+07 3.34E+06 - - - 1.2354 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.16232.16232.2 0.00018 20-Nov K.LLDSITVPVAR.A sp|O00203|AP3B1_HUMAN 1 1182.6972 1.37 12840 16232 2 1182.696501 592.3559 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3310.1 - 1.62E+06 - - - -0.6105 - 2.111 0.405 - 329.7 1 2 0 -0.0007 11 0 0 0 2.79E+07 2.03E+07 - - - 4.0534 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.16234.16234.2 0.000735 18-Nov R.LTPLQLEIQR[166.11].V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1219.7164 1.19 12842 16234 2 1219.715632 610.8655 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 3310.3 - 1.37E+06 - - - -0.6231 - 1.851 0.411 - 473.8 1 2 0 -0.0008 10 0 0 0 5.51E+07 4.63E+07 - - - 3.7951 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.16235.16235.2 0.0174 18-Sep R.LTPLQLEIQR.V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1209.7081 1.19 12843 16235 2 1209.708221 605.8613 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 3310.4 - 1.20E+06 - - - 0.0818 - 1.633 0.261 - 346.1 1 2 0 0.0001 10 0 0 0 5.51E+07 4.63E+07 - - - 2.3376 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.16243.16243.2 0.0407 12-Jul R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 34.97 12849 16243 2 806.392572 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 3311.3 - 3.00E+06 - - - 0.3782 - 1.547 0.246 - 188.2 1 2 0 0.0003 7 0 0 0 5.14E+07 1.47E+06 - - - 2.2404 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.16244.16244.2 0.007 12-Aug K.MFEFYER.V "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 13 1020.4375 2.23 12850 16244 2 1020.438776 511.226 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3311.5 - 1.15E+06 - - - 1.2475 - 1.325 0.189 - 306.6 1 2 0 0.0013 7 0 0 0 2.44E+07 1.09E+07 - - - 1.3282 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.16251.16251.2 0.000453 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 369.91 12854 16251 2 1154.643288 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3312.4 - 725774 - - - 0.5309 - 1.998 0.468 - 262 1 2 0 0.0006 10 0 0 0 6.85E+09 1.85E+07 - - - 4.4294 0.9926 230117_WJC_METTL3_WT_vs_EV_F02.16255.16255.2 0.347 16-Jul R.LLGLEEQLR.A "sp|P28290|ITPI2_HUMAN,tr|E9PHV5|E9PHV5_HUMAN,tr|E7EUL7|E7EUL7_HUMAN" 3 1069.6132 3.29 12858 16255 2 1069.613161 535.8139 Protein ITPRID2 OS=Homo sapiens OX=9606 GN=ITPRID2 PE=1 SV=3 4.53 3312.8 - 484941 - - - 0.0019 - 1.207 0.188 - 110.6 1 2 0 0 9 0 0 0 1.10E+07 3.34E+06 - - - 0.9739 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16259.16259.2 0.00944 13/22 K.LGALTAEEIALK.M sp|Q13601|KRR1_HUMAN 1 1227.7075 1.2 12860 16259 2 1227.710325 614.861 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3313.3 - 1.25E+06 - - - 2.3385 - 2.059 0.42 - 442 1 2 0 0.0029 12 0 0 0 1.73E+08 1.45E+08 - - - 4.0425 1 230117_WJC_METTL3_WT_vs_EV_F02.16266.16266.2 0.000466 14/22 K.LGALTAEEIALK[136.11].M sp|Q13601|KRR1_HUMAN 1 1235.7217 1.19 12865 16266 2 1235.72044 618.8681 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3314 - 2.47E+06 - - - -0.9824 - 2.416 0.496 - 551.3 1 2 0 -0.0012 12 0 0 0 1.73E+08 1.45E+08 - - - 5.0251 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.16269.16269.2 0.0115 14-Jun K.FYSFALDK.T sp|Q96T58|MINT_HUMAN 1 989.4858 1.12 12868 16269 2 989.485981 495.7502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.83 3314.4 - 404443 - - - 0.1486 - 1.293 0.3 - 76.8 1 2 0 0.0001 8 0 0 0 2.62E+07 2.35E+07 - - - 2.0317 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.16270.16270.2 0.0015 22-Oct R.VFASELNAGIIK[136.11].T "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1268.722 1.46 12869 16270 2 1268.724041 635.3683 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.97 3314.5 - 355835 - - - 1.6182 - 1.782 0.371 - 240.8 1 2 0 0.0021 12 0 0 0 1.95E+07 1.34E+07 - - - 3.3007 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16275.16275.2 0.00304 18-Dec K.LLADELISPK.D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1097.6332 1.04 12872 16275 2 1097.634427 549.8239 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3315.2 - 1.73E+06 - - - 1.0942 - 2.069 0.316 - 370.2 1 2 0 0.0012 10 0 0 0 7.10E+07 6.81E+07 - - - 3.4041 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.16276.16276.2 9.31 12-Jul K.DVLLPLK.S sp|Q9Y385|UB2J1_HUMAN 1 796.5058 1.12 12873 16276 2 796.505898 399.2602 Ubiquitin-conjugating enzyme E2 J1 OS=Homo sapiens OX=9606 GN=UBE2J1 PE=1 SV=2 5.84 3315.3 - 614534 - - - 0.0716 - 1.555 0.159 - 214.8 1 2 0 0.0001 7 0 0 0 1.15E+07 1.02E+07 - - - 1.6142 0.9914 230117_WJC_METTL3_WT_vs_EV_F02.16278.16278.2 0.0011 18-Sep K.IPVSGPFLVK.T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1055.6379 1.28 12875 16278 2 1055.63448 528.8262 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3315.6 - 381704 - - - -3.2568 - 1.629 0.309 - 148.9 1 2 0 -0.0034 10 0 0 0 1.70E+08 1.33E+08 - - - 2.6843 0.998 230117_WJC_METTL3_WT_vs_EV_F02.16281.16281.2 0.851 12-Jul K.LFQLYPR.N sp|Q8IXM3|RM41_HUMAN 1 935.5229 1.65 12876 16281 2 935.52479 468.7687 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 8.75 3316 - 3.01E+06 - - - 2.0331 - 1.629 0.166 - 208.5 1 2 0 0.0019 7 0 0 0 1.28E+08 7.79E+07 - - - 1.8126 0.9918 230117_WJC_METTL3_WT_vs_EV_F02.16282.16282.2 0.0258 12-Jul K.LMVIFSK.V "sp|Q9BRK5|CAB45_HUMAN,tr|A0A5F9UJX7|A0A5F9UJX7_HUMAN,tr|A0A5F9UP49|A0A5F9UP49_HUMAN,tr|G3V1E2|G3V1E2_HUMAN,tr|H0Y3T6|H0Y3T6_HUMAN" 5 836.483 0.27 12877 16282 2 836.482545 419.2488 45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1 8.75 3316.1 - 550358 - - - -0.5404 - 1.456 0.122 - 150.3 1 2 0 -0.0005 7 0 0 0 3.09E+07 1.15E+08 - - - 1.1324 0.9649 230117_WJC_METTL3_WT_vs_EV_F02.16288.16288.2 0.00149 18-Nov K.LGLTEDQFIR.T "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1190.6295 2.61 12881 16288 2 1190.622342 596.322 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.37 3316.9 - 628411 - - - -6.0439 - 1.633 0.359 - 297.5 1 2 0 -0.0072 10 0 0 0 1.51E+07 5.78E+06 - - - 3.0592 0.9954 230117_WJC_METTL3_WT_vs_EV_F02.16295.16295.2 0.0818 18-Aug K.IPVSGPFLVK[136.11].T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1063.6521 1.28 12884 16295 2 1063.651937 532.8333 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3317.8 - 1.23E+06 - - - -0.1702 - 1.365 0.205 - 139.6 1 2 0 -0.0002 10 0 0 0 1.70E+08 1.33E+08 - - - 1.4236 0.9872 230117_WJC_METTL3_WT_vs_EV_F02.16300.16300.2 1.9 14-Jul R.EPLLTLVK.E sp|Q13200|PSMD2_HUMAN 1 911.5692 1.87 12887 16300 2 911.568696 456.7919 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 6.1 3318.3 - 1.18E+06 - - - -0.5189 - 1.289 0.133 - 141.7 1 2 0 -0.0005 8 0 0 0 2.19E+08 1.17E+08 - - - 0.7888 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.16306.16306.2 0.665 16-Jul K.VILTSPLIR[166.11].D sp|Q96SI9|STRBP_HUMAN 1 1020.6571 1.95 12893 16306 2 1020.657477 511.3358 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 9.72 3319.1 - 399674 - - - 0.3821 - 1.372 0.292 - 115.4 1 2 0 0.0004 9 0 0 0 5.46E+07 2.80E+07 - - - 2.1126 1 230117_WJC_METTL3_WT_vs_EV_F02.16313.16313.2 0.00221 14/22 K.VLVALASEELAK[136.11].G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1249.7373 1.66 12897 16313 2 1249.741328 625.8759 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.53 3320 - 719332 - - - 3.2199 - 2.587 0.432 - 678 1 2 0 0.004 12 0 0 0 5.97E+07 3.60E+07 - - - 4.7314 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.16319.16319.2 0.000134 13/22 K.VLVALASEELAK.G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1241.7231 1.66 12900 16319 2 1241.723344 621.8688 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.53 3320.7 - 2.22E+06 - - - 0.1933 - 2.429 0.433 - 468.5 1 2 0 0.0002 12 0 0 0 5.98E+07 3.60E+07 - - - 4.5742 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.16320.16320.2 0.101 20-Oct R.IDALLAVDPPR.A sp|P50219|MNX1_HUMAN 1 1178.6659 1.9 12901 16320 2 1178.668618 590.3402 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3320.9 - 756146 - - - 2.2865 - 2.123 0.303 - 297.5 1 2 0 0.0027 11 0 0 0 3.31E+07 1.74E+07 - - - 3.3147 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.16323.16323.2 0.0144 18-Sep K.LGLTEDQFIR[166.11].T "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1200.6378 2.61 12904 16323 2 1200.638844 601.3262 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.37 3321.3 - 380531 - - - 0.8629 - 1.73 0.272 - 163.9 1 2 0 0.001 10 0 0 0 1.51E+07 5.78E+06 - - - 2.5796 1 230117_WJC_METTL3_WT_vs_EV_F02.16331.16331.2 7.93E-05 20-Nov R.LLTGVEYVVGR.K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1204.6816 1.63 12909 16331 2 1204.684075 603.3481 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3322.4 - 214194 - - - 2.0769 - 2.353 0.476 - 351.2 1 2 0 0.0025 11 0 0 0 3.23E+07 1.99E+07 - - - 4.8708 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.16335.16335.2 0.0619 16-Nov R.IGLINDMVR[166.11].F sp|Q14152|EIF3A_HUMAN 1 1039.5724 1.07 12911 16335 2 1039.572194 520.7935 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.84 3322.9 - 586407 - - - -0.1703 - 1.784 0.241 - 298 1 2 0 -0.0002 9 0 0 0 7.52E+07 7.03E+07 - - - 2.4956 1 230117_WJC_METTL3_WT_vs_EV_F02.16343.16343.2 1.85E-05 20-Nov R.LLTGVEYVVGR[166.11].K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1214.6898 1.63 12917 16343 2 1214.691888 608.3522 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3323.8 - 510382 - - - 1.6836 - 2.385 0.506 - 393.2 1 2 0 0.002 11 0 0 0 3.23E+07 1.99E+07 - - - 5.1291 0.9593 230117_WJC_METTL3_WT_vs_EV_F02.16348.16348.2 0.0556 12-Jul K.LMFEELR.N sp|Q9Y3I0|RTCB_HUMAN 1 936.4739 0.97 12920 16348 2 936.479784 469.2442 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.53 3324.4 - 2.16E+06 - - - 6.2949 - 1.32 0.217 - 148.1 1 2 0 0.0059 7 0 0 0 7.24E+07 7.43E+07 - - - 1.5216 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.16350.16350.2 0.069 16-Aug R.IGFGSFVEK[136.11].T "sp|P05556|ITB1_HUMAN,sp|P18564|ITB6_HUMAN,tr|A0A7I2V2F9|A0A7I2V2F9_HUMAN,tr|A0A087WXP3|A0A087WXP3_HUMAN,tr|A0A7I2V5T3|A0A7I2V5T3_HUMAN,tr|H7C4K3|H7C4K3_HUMAN,tr|E7EUI6|E7EUI6_HUMAN,tr|E9PEE8|E9PEE8_HUMAN,tr|A0A7I2V5Z8|A0A7I2V5Z8_HUMAN,tr|A0A7I2V348|A0A7I2V348_HUMAN,tr|C9JPK5|C9JPK5_HUMAN" 11 990.5266 3.45 12922 16350 2 990.528626 496.2706 Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1 PE=1 SV=2 6 3324.7 - 356805 - - - 2.0625 - 1.588 0.255 - 91.9 1 2 0 0.002 9 0 0 0 1.68E+07 4.87E+06 - - - 2.2618 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.16351.16351.2 0.082 20-Jun K.VLEVPPVVYSR[166.11].Q "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1266.7211 0.55 12923 16351 2 1266.723013 634.3678 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 5.97 3324.8 - 326682 - - - 1.4763 - 1.612 0.209 - 137.9 1 2 0 0.0019 11 0 0 0 7.74E+06 1.41E+07 - - - 1.8758 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.16357.16357.2 0.00581 16-Jun R.LFGTTVTFK[136.11].F "sp|Q15904|VAS1_HUMAN,tr|A0A0C4DGX8|A0A0C4DGX8_HUMAN" 2 1020.5735 5.01 12927 16357 2 1020.575154 511.294 V-type proton ATPase subunit S1 OS=Homo sapiens OX=9606 GN=ATP6AP1 PE=1 SV=2 8.75 3325.5 - 3.48E+06 - - - 1.5883 - 1.348 0.294 - 68.3 1 2 0 0.0016 9 0 0 0 1.56E+08 3.10E+07 - - - 2.0759 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.16358.16358.2 0.0806 16-Sep K.ALLSTVLSR.S "sp|Q5H9F3|BCORL_HUMAN,tr|H7C4B2|H7C4B2_HUMAN" 2 958.5811 2.37 12928 16358 2 958.580405 480.2978 BCL-6 corepressor-like protein 1 OS=Homo sapiens OX=9606 GN=BCORL1 PE=1 SV=1 9.79 3325.6 - 1.85E+06 - - - -0.7574 - 1.813 0.203 - 183.7 1 2 0 -0.0007 9 0 0 0 1.11E+07 4.67E+06 - - - 2.2614 0.9953 230117_WJC_METTL3_WT_vs_EV_F02.16363.16363.2 0.745 18-Sep K.LVALAVIDEK.N sp|Q96JJ7|TMX3_HUMAN 1 1069.6383 1.79 12933 16363 2 1069.638257 535.8264 Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2 4.37 3326.2 - 1.07E+06 - - - -0.0505 - 1.633 0.126 - 122.9 1 2 0 -0.0001 10 0 0 0 1.54E+07 8.57E+06 - - - 1.3405 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.16370.16370.2 0.125 18-Aug K.LVALAVIDEK[136.11].N sp|Q96JJ7|TMX3_HUMAN 1 1077.6525 1.79 12938 16370 2 1077.652644 539.8335 Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2 4.37 3327.1 - 612359 - - - 0.1234 - 2.056 0.326 - 91 1 2 0 0.0001 10 0 0 0 1.54E+07 8.57E+06 - - - 3.4607 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.16373.16373.2 0.791 12-Jul K.LIIFDAR.Q "sp|Q13613|MTMR1_HUMAN,tr|Q8NEC6|Q8NEC6_HUMAN,tr|F8WA39|F8WA39_HUMAN,tr|H0YDX3|H0YDX3_HUMAN" 4 846.4963 4.56 12940 16373 2 846.497032 424.2554 Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4 5.84 3327.4 - 2.39E+06 - - - 0.8187 - 1.545 0.16 - 170 1 2 0 0.0007 7 0 0 0 9.83E+07 2.16E+07 - - - 1.6009 0.9886 230117_WJC_METTL3_WT_vs_EV_F02.16376.16376.2 0.38 12-Jul K.LWVLETK[136.11].E "sp|Q15061|WDR43_HUMAN,tr|C9JEE7|C9JEE7_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 3 895.5259 7.55 12943 16376 2 895.524383 448.7702 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3327.7 - 472158 - - - -1.6426 - 1.396 0.18 - 122.7 1 2 0 -0.0015 7 0 0 0 3.74E+08 4.95E+07 - - - 1.4271 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16380.16380.2 0.0196 14-Sep K.VTNLLMLK[136.11].G "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|B4DI28|B4DI28_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|X6R242|X6R242_HUMAN,tr|A0A6Q8PH43|A0A6Q8PH43_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 18 938.5714 1.16 12945 16380 2 938.572698 470.293 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.72 3328.2 - 8.75E+06 - - - 1.3574 - 1.988 0.353 - 241.1 1 2 0 0.0013 8 0 0 0 7.30E+08 6.27E+08 - - - 3.7202 0.916 230117_WJC_METTL3_WT_vs_EV_F02.16382.16382.2 0.00292 20-Sep R.VGAGAPVYLAA.V "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 14 987.5389 - 12947 16382 2 987.539414 494.7767 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 5.49 3328.3 - 782109 - - - 0.4881 - 1.504 0.306 - 105.8 1 1 0 0.0005 11 0 0 0 - - - - - 2.405 0.997 230117_WJC_METTL3_WT_vs_EV_F02.16390.16390.2 0.167 12-Sep R.LSAILFK.L "sp|Q9NSV4|DIAP3_HUMAN,sp|Q12830|BPTF_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|J3KSK9|J3KSK9_HUMAN,tr|J3QQQ8|J3QQQ8_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN" 7 790.4953 1.21 12952 16390 2 790.496467 396.2549 Protein diaphanous homolog 3 OS=Homo sapiens OX=9606 GN=DIAPH3 PE=1 SV=4 8.75 3329.3 - 1.07E+06 - - - 1.5067 - 1.531 0.133 - 240.7 1 2 0 0.0012 7 0 0 0 1.77E+07 1.46E+07 - - - 1.3725 0.9956 230117_WJC_METTL3_WT_vs_EV_F02.16391.16391.2 17.1 14-Aug K.ALLPVLAK[136.11].R "sp|O75127|PTCD1_HUMAN,tr|G3V325|G3V325_HUMAN" 2 831.5673 1.33 12953 16391 2 831.567487 416.7909 "Pentatricopeptide repeat-containing protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD1 PE=1 SV=2" 8.8 3329.4 - 590304 - - - 0.1948 - 1.221 0.243 - 137.6 2 2 0 0.0002 8 0 0 0 1.43E+07 1.08E+07 - - - 1.3035 0.864 230117_WJC_METTL3_WT_vs_EV_F02.16395.16395.2 2.29 12-Jun R.EAYYWLR.H sp|P46977|STT3A_HUMAN 1 999.4814 1.3 12955 16395 2 999.481732 500.748 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6.1 3329.9 - 664708 - - - 0.3152 - 0.932 0.008 - 99.1 1 2 0 0.0003 7 0 0 0 3.54E+07 2.72E+07 - - - -1.1231 0.9863 230117_WJC_METTL3_WT_vs_EV_F02.16396.16396.2 1.66 14-Jul R.ALDIPLVK.N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 867.543 1.25 12956 16396 2 867.545036 434.7788 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3330 - 2.31E+06 - - - 2.3999 - 1.193 0.117 - 168.5 1 2 0 0.0021 8 0 0 0 8.87E+07 7.10E+07 - - - 0.4367 0.9731 230117_WJC_METTL3_WT_vs_EV_F02.16397.16397.2 4.58 26-Jul R.IAGPAIPSVVAYPK.R "tr|A0A7I2YQF4|A0A7I2YQF4_HUMAN,tr|A0A7I2V549|A0A7I2V549_HUMAN,tr|A0A7I2V602|A0A7I2V602_HUMAN" 3 1381.7969 0.75 12957 16397 2 1381.79819 691.9057 Non-specific serine\threonine protein kinase OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=1 8.59 3330.1 - 526722 - - - 0.9068 - 1.156 0.058 - 121.1 1 2 0 0.0013 14 0 0 0 1.85E+07 2.45E+07 - - - -0.1672 0.9934 230117_WJC_METTL3_WT_vs_EV_F02.16398.16398.2 0.101 20-Oct R.IDALLAVDPPR[166.11].A sp|P50219|MNX1_HUMAN 1 1188.6742 1.9 12958 16398 2 1188.679394 595.3444 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3330.2 - 314456 - - - 4.3755 - 2.049 0.14 - 313.7 1 2 0 0.0052 11 0 0 0 3.20E+07 1.69E+07 - - - 2.014 0.9792 230117_WJC_METTL3_WT_vs_EV_F02.16404.16404.2 0.135 18-Jul K.GVEGSAGAGK.E tr|A0A5F9UQ55|A0A5F9UQ55_HUMAN 1 831.4086 0.36 12962 16404 2 831.412817 416.7116 F-box\WD repeat-containing protein 4 OS=Homo sapiens OX=9606 GN=FBXW4 PE=1 SV=1 6 3331.1 - 671570 - - - 5.0168 - 1.44 0.226 - 57.9 6 2 0 0.0042 10 0 0 0 2.00E+07 5.63E+07 - - - 1.3792 0.9607 230117_WJC_METTL3_WT_vs_EV_F02.16405.16405.2 0.125 12-May R.EAYYWLR[166.11].H sp|P46977|STT3A_HUMAN 1 1009.4897 1.31 12963 16405 2 1009.490235 505.7521 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6.1 3331.1 - 890457 - - - 0.5428 - 1.154 0.021 - 102.9 1 2 0 0.0005 7 0 0 0 3.48E+07 2.66E+07 - - - -0.3502 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.16417.16417.2 2.47 14-Jul R.ALDIPLVK[136.11].N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 875.5572 1.25 12971 16417 2 875.558479 438.7859 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3332.5 - 4.22E+06 - - - 1.5133 - 1.345 0.222 - 144.6 1 2 0 0.0013 8 0 0 0 8.87E+07 7.10E+07 - - - 1.5742 0.9593 230117_WJC_METTL3_WT_vs_EV_F02.16420.16420.2 1.76 16-Jul R.LVLQYAPSA.- "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN" 2 960.528 - 12974 16420 2 960.527073 481.2713 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 5.52 3332.8 - 1.19E+06 - - - -0.9995 - 1.104 0.115 - 91.2 1 2 0 -0.001 9 0 0 0 - - - - - 0.1763 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.16422.16422.2 0.459 12-Aug R.LFEGIIK.G "sp|O14936|CSKP_HUMAN,tr|A0A2U3TZM1|A0A2U3TZM1_HUMAN,tr|A0A2R8YFN5|A0A2R8YFN5_HUMAN,tr|A0A2R8YEK3|A0A2R8YEK3_HUMAN,tr|A0A2R8YE77|A0A2R8YE77_HUMAN,tr|A0A2R8Y6F8|A0A2R8Y6F8_HUMAN,tr|Q5JS79|Q5JS79_HUMAN,tr|A0A2R8Y3B3|A0A2R8Y3B3_HUMAN,tr|A0A2R8Y6D8|A0A2R8Y6D8_HUMAN,tr|A0A2U3TZN6|A0A2U3TZN6_HUMAN,tr|A0A2U3TZM4|A0A2U3TZM4_HUMAN,tr|A0A2R8YEJ7|A0A2R8YEJ7_HUMAN,tr|A0A7I2RJN6|A0A7I2RJN6_HUMAN" 13 818.4902 0.33 12976 16422 2 818.490754 410.2524 Peripheral plasma membrane protein CASK OS=Homo sapiens OX=9606 GN=CASK PE=1 SV=3 6 3333 - 865119 - - - 0.6879 - 1.645 0.13 - 166.4 1 2 0 0.0006 7 0 0 0 1.26E+07 3.81E+07 - - - 1.5781 0.999 230117_WJC_METTL3_WT_vs_EV_F02.16426.16426.2 0.00366 22-Jul R.MPGSVIPPPLVR[166.11].G sp|Q86YP4|P66A_HUMAN 1 1271.7299 4.04 12980 16426 2 1271.729811 636.8722 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.5 3333.5 - 160290 - - - -0.0967 - 1.599 0.356 - 102.7 1 2 0 -0.0001 12 0 0 0 1.28E+07 3.17E+06 - - - 2.9054 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.16431.16431.2 0.0427 12-Jun K.LWYTLDR[166.11].A sp|P00387|NB5R3_HUMAN 1 975.5053 2.1 12983 16431 2 975.505076 488.7599 NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3 5.84 3334.1 - 1.43E+06 - - - -0.2676 - 1.534 0.206 - 115.6 1 2 0 -0.0003 7 0 0 0 3.39E+07 1.61E+07 - - - 1.9182 1 230117_WJC_METTL3_WT_vs_EV_F02.16435.16435.2 7.05E-06 26-Dec F.LLIGGGTAAFAAAR.S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1287.7299 5.1 12987 16435 2 1287.733104 644.8722 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3334.6 - 436729 - - - 2.4726 - 2.312 0.571 - 436.6 1 1 0 0.0032 14 0 0 0 8.51E+06 1.67E+06 - - - 5.3606 0.999 230117_WJC_METTL3_WT_vs_EV_F02.16439.16439.2 0.00446 12-Aug K.FVSFLGR[166.11].T "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 834.4627 1.23 12989 16439 2 834.462869 418.2386 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 9.75 3335.1 - 1.73E+06 - - - 0.1498 - 1.489 0.326 - 208.8 1 2 0 0.0001 7 0 0 0 1.75E+08 1.43E+08 - - - 2.7102 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.16440.16440.2 0.0291 12-Jun K.LMFEELR[166.11].N sp|Q9Y3I0|RTCB_HUMAN 1 946.4822 0.97 12990 16440 2 946.483803 474.2484 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.53 3335.2 - 1.79E+06 - - - 1.737 - 1.275 0.311 - 146.4 1 2 0 0.0016 7 0 0 0 7.24E+07 7.44E+07 - - - 2.1073 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.16446.16446.2 0.00121 16-Aug K.GPLMMYISK.M sp|P13639|EF2_HUMAN 1 1038.5242 0.1 12995 16446 2 1038.525912 520.2694 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 3335.8 - 1.51E+06 - - - 1.6389 - 1.917 0.451 - 276.8 1 2 0 0.0017 9 0 0 0 4.42E+07 4.57E+08 - - - 4.2542 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.16447.16447.2 0.0855 12-Aug K.FVSFLGR.T "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 824.4545 1.12 12996 16447 2 824.455767 413.2345 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 9.75 3335.9 - 2.26E+06 - - - 1.5683 - 1.494 0.336 - 203.8 1 2 0 0.0013 7 0 0 0 1.59E+08 1.42E+08 - - - 2.7943 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.16455.16455.2 0.00424 14-Aug K.VTNLLMLK.G "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|B4DI28|B4DI28_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|X6R242|X6R242_HUMAN,tr|A0A6Q8PH43|A0A6Q8PH43_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 18 930.5572 1.16 13003 16455 2 930.558844 466.2859 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.72 3336.7 - 2.90E+07 - - - 1.7409 - 1.754 0.353 - 198.9 1 2 0 0.0016 8 0 0 0 7.30E+08 6.27E+08 - - - 3.3424 1 230117_WJC_METTL3_WT_vs_EV_F02.16456.16456.2 4.23E-05 18-Dec K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 15.69 13004 16456 2 1146.630574 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3336.8 - 4.26E+06 - - - 1.8306 - 2.16 0.497 - 401.9 1 2 0 0.0021 10 0 0 0 1.80E+08 1.15E+07 - - - 4.8608 0.8493 230117_WJC_METTL3_WT_vs_EV_F02.16457.16457.2 0.124 12-Jul Q.AAILHLK.R "sp|Q68DA7|FMN1_HUMAN,sp|Q8NHP7|EXD1_HUMAN,tr|H0YM30|H0YM30_HUMAN,tr|A0A5F9ZHS8|A0A5F9ZHS8_HUMAN" 4 764.4909 1.81 13005 16457 2 764.492189 383.2527 Formin-1 OS=Homo sapiens OX=9606 GN=FMN1 PE=1 SV=3 8.8 3336.9 - 3.27E+06 - - - 1.7397 - 1.263 0.254 - 185 1 1 0 0.0013 7 0 0 0 5.90E+07 3.26E+07 - - - 1.6565 0.9576 230117_WJC_METTL3_WT_vs_EV_F02.16458.16458.2 0.00524 12-Aug Q.AAILHLK[136.11].R "sp|Q68DA7|FMN1_HUMAN,sp|Q8NHP7|EXD1_HUMAN,tr|H0YM30|H0YM30_HUMAN,tr|A0A5F9ZHS8|A0A5F9ZHS8_HUMAN" 4 772.5051 1.78 13006 16458 2 772.5064 387.2598 Formin-1 OS=Homo sapiens OX=9606 GN=FMN1 PE=1 SV=3 8.8 3336.9 - 2.53E+06 - - - 1.7359 - 1.567 0.36 - 248.3 1 1 0 0.0013 7 0 0 0 6.05E+07 3.40E+07 - - - 3.1227 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16460.16460.2 0.00318 16-Dec R.SPVYLTVLK[136.11].H "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1026.6205 1.64 13008 16460 2 1026.623209 514.3175 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 8.31 3337.2 - 874848 - - - 2.6553 - 2.22 0.401 - 455.9 1 2 0 0.0027 9 0 0 0 1.54E+07 9.39E+06 - - - 4.3092 0.9769 230117_WJC_METTL3_WT_vs_EV_F02.16462.16462.2 0.00424 13/26 F.LLIGGGTAAFAAAR[166.11].S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1297.7382 5.1 13010 16462 2 1297.740993 649.8764 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3337.4 - 154855 - - - 2.1599 - 2.258 0.473 - 431 1 1 0 0.0028 14 0 0 0 8.51E+06 1.67E+06 - - - 4.5776 0.999 230117_WJC_METTL3_WT_vs_EV_F02.16465.16465.2 0.0542 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.09 13012 16465 2 1235.762915 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3337.8 - 1.93E+06 - - - 2.231 - 1.95 0.232 - 219.3 1 2 0 0.0028 11 0 0 0 2.96E+07 2.72E+07 - - - 2.5603 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16466.16466.2 0.0013 13/20 K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.09 13013 16466 2 1245.771078 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3337.9 - 1.77E+06 - - - 2.1272 - 2.272 0.344 - 474.2 1 2 0 0.0027 11 0 0 0 2.96E+07 2.72E+07 - - - 3.801 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.16467.16467.2 0.00113 14-Aug K.VIFLENYR.V "sp|P06737|PYGL_HUMAN,sp|P11217|PYGM_HUMAN,sp|P11216|PYGB_HUMAN,tr|E9PK47|E9PK47_HUMAN,tr|H0Y4Z6|H0Y4Z6_HUMAN" 5 1052.5655 5.38 13014 16467 2 1052.569207 527.29 "Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL PE=1 SV=4" 5.97 3338 - 4.52E+06 - - - 3.5399 - 1.88 0.436 - 260.3 1 2 0 0.0037 8 0 0 0 4.57E+07 8.49E+06 - - - 4.164 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.16469.16469.2 5.9 16-Aug R.SLFVVVGDR[166.11].G "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 1000.5581 0.06 13016 16469 2 1000.560737 501.2863 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.55 3338.1 - 1.69E+06 - - - 2.6345 - 1.531 0.186 - 167 1 2 0 0.0026 9 0 0 0 3.33E+06 5.79E+07 - - - 1.6462 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.16470.16470.2 0.000607 16-Sep R.SLFVVVGDR.G "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 990.5498 0.48 13017 16470 2 990.553861 496.2822 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.55 3338.2 - 1.18E+06 - - - 4.0684 - 2.119 0.451 - 276 1 2 0 0.004 9 0 0 0 2.06E+07 4.30E+07 - - - 4.5433 0.9832 230117_WJC_METTL3_WT_vs_EV_F02.16472.16472.2 3.02 12-Oct K.LPLLLSR.M "sp|P49902|5NTC_HUMAN,sp|O95866|G6B_HUMAN,tr|A0A140T9L8|A0A140T9L8_HUMAN,tr|A0A6Q8PHB5|A0A6Q8PHB5_HUMAN,tr|A0A140T9V1|A0A140T9V1_HUMAN,tr|A0A6Q8PHP0|A0A6Q8PHP0_HUMAN,tr|B7ZLJ5|B7ZLJ5_HUMAN,tr|A0A0G2JJG8|A0A0G2JJG8_HUMAN,tr|F8WDG3|F8WDG3_HUMAN,tr|Q5JUV4|Q5JUV4_HUMAN" 10 810.5327 0.75 13019 16472 2 810.535844 406.2736 Cytosolic purine 5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5C2 PE=1 SV=1 9.75 3338.5 - 489990 - - - 3.8493 - 1.733 0.019 - 428 1 2 0 0.0031 7 0 0 0 1.12E+07 1.51E+07 - - - 0.9226 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.16474.16474.2 0.00111 16-Sep K.GLIDYETFK.E sp|P15924|DESP_HUMAN 1 1084.5441 2.68 13021 16474 2 1084.54844 543.2793 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3338.8 - 373762 - - - 4.0229 - 1.792 0.344 - 196 1 2 0 0.0044 9 0 0 0 5.04E+06 1.88E+06 - - - 3.268 0.9954 230117_WJC_METTL3_WT_vs_EV_F02.16480.16480.2 0.0463 14-Aug R.LIGWGQIR[166.11].R "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 951.553 0.86 13026 16480 2 951.556191 476.7838 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 9.75 3339.5 - 4.01E+06 - - - 3.3997 - 1.384 0.233 - 182.8 1 2 0 0.0032 8 0 0 0 5.01E+07 5.84E+07 - - - 1.741 1 230117_WJC_METTL3_WT_vs_EV_F02.16481.16481.2 1.49E-05 16-Sep K.GPLMMYISK[136.11].M sp|P13639|EF2_HUMAN 1 1046.5384 1.81 13027 16481 2 1046.540873 524.2765 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 3339.6 - 959460 - - - 2.3535 - 1.99 0.542 - 383.4 1 2 0 0.0025 9 0 0 0 2.31E+07 1.28E+07 - - - 5.0342 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.16482.16482.2 0.57 14-Jul K.VIILSLDR.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 927.5753 2.35 13028 16482 2 927.577014 464.7949 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.81 3339.6 - 1.03E+07 - - - 1.8295 - 1.662 0.27 - 196.8 1 2 0 0.0017 8 0 0 0 1.99E+08 8.49E+07 - - - 2.5669 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.16483.16483.2 0.101 14-Aug R.LIGWGQIR.R "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 941.5447 0.84 13029 16483 2 941.546398 471.7796 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 9.75 3339.6 - 4.12E+06 - - - 1.8183 - 1.639 0.239 - 176.9 1 2 0 0.0017 8 0 0 0 4.88E+07 5.80E+07 - - - 2.2959 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.16492.16492.2 7.44E-05 18-Aug K.AAPEMVSLLK[136.11].R "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN,tr|K7EQ99|K7EQ99_HUMAN" 3 1065.5984 1.17 13036 16492 2 1065.601573 533.8065 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 6.05 3340.8 - 1.05E+06 - - - 3.0086 - 1.638 0.429 - 194.9 1 2 0 0.0032 10 0 0 0 4.29E+07 3.66E+07 - - - 3.586 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.16494.16494.2 0.51 14-Sep K.LLELLPGK.V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 881.5586 2.18 13038 16494 2 881.560355 441.7866 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3340.9 - 1.53E+06 - - - 1.9851 - 1.75 0.195 - 256.8 1 2 0 0.0018 8 0 0 0 7.44E+07 3.42E+07 - - - 2.1685 0.9857 230117_WJC_METTL3_WT_vs_EV_F02.16500.16500.2 0.0492 14-Jul K.GGNPFLFR.Q "sp|Q9HAS0|NJMU_HUMAN,tr|J9JIC5|J9JIC5_HUMAN" 2 906.4712 1.76 13044 16500 2 906.469512 454.2429 Protein Njmu-R1 OS=Homo sapiens OX=9606 GN=C17orf75 PE=1 SV=2 9.75 3341.7 - 257187 - - - -1.8467 - 1.248 0.222 - 133.4 1 2 0 -0.0017 8 0 0 0 2.18E+06 1.23E+06 - - - 1.3483 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.16505.16505.2 0.0903 12-Jul R.SFDLLVK[136.11].N sp|Q9HB71|CYBP_HUMAN 1 828.4837 2.18 13047 16505 2 828.486235 415.2491 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 5.55 3342.3 - 3.82E+06 - - - 3.1141 - 1.364 0.338 - 181.5 1 2 0 0.0026 7 0 0 0 9.76E+07 4.47E+07 - - - 2.5202 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.16506.16506.2 0.000176 12-Aug K.YYTLFGR.S sp|P07814|SYEP_HUMAN 1 918.46 1.12 13048 16506 2 918.461914 460.2373 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.59 3342.3 - 2.65E+06 - - - 2.1351 - 1.591 0.415 - 191 1 2 0 0.002 7 0 0 0 7.16E+07 6.39E+07 - - - 3.5769 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16507.16507.2 0.0112 16-Nov K.NAIVVLIPK.Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 965.6274 2.08 13049 16507 2 965.629615 483.821 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3342.4 - 2.39E+06 - - - 2.3425 - 1.693 0.453 - 303.3 1 2 0 0.0023 9 0 0 0 1.42E+08 6.81E+07 - - - 3.9093 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.16508.16508.2 0.518 14-Sep K.LLELLPGK[136.11].V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 889.5728 2.2 13050 16508 2 889.574241 445.7937 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3342.5 - 2.02E+06 - - - 1.6143 - 1.533 0.228 - 234.3 1 2 0 0.0014 8 0 0 0 7.52E+07 3.42E+07 - - - 2.0131 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16509.16509.2 0.335 16-Sep K.NAIVVLIPK[136.11].Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 973.6416 2.08 13051 16509 2 973.643326 487.8281 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3342.6 - 1.19E+06 - - - 1.821 - 1.76 0.396 - 205.5 1 2 0 0.0018 9 0 0 0 1.42E+08 6.81E+07 - - - 3.6008 0.993 230117_WJC_METTL3_WT_vs_EV_F02.16511.16511.2 0.724 16-Jun R.LIPDFPVAR.S sp|Q96S55|WRIP1_HUMAN 1 1026.5862 5.15 13053 16511 2 1026.58686 514.3004 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 5.84 3342.7 - 573357 - - - 0.6273 - 1.246 0.171 - 89.1 2 2 0 0.0006 9 0 0 0 3.55E+07 6.91E+06 - - - 0.8056 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.16512.16512.2 0.00477 20-Aug R.LVMELSGEMVR.K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1262.6363 2.56 13054 16512 2 1262.642091 632.3254 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3342.9 - 272043 - - - 4.6031 - 1.617 0.323 - 139.5 1 2 0 0.0058 11 0 0 0 1.30E+07 5.07E+06 - - - 2.7249 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.16516.16516.2 0.0127 12-Aug R.SFDLLVK.N sp|Q9HB71|CYBP_HUMAN 1 820.4695 2.16 13056 16516 2 820.472155 411.242 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 5.55 3343.4 - 1.17E+07 - - - 3.2908 - 1.304 0.338 - 232.1 1 2 0 0.0027 7 0 0 0 9.81E+07 4.54E+07 - - - 2.3777 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.16519.16519.2 0.00361 20-Jul R.LVMELSGEMVR[166.11].K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1272.6445 2.56 13059 16519 2 1272.645538 637.3296 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3343.7 - 430444 - - - 0.7771 - 1.522 0.331 - 119.5 1 2 0 0.001 11 0 0 0 1.30E+07 5.07E+06 - - - 2.6217 0.999 230117_WJC_METTL3_WT_vs_EV_F02.16531.16531.2 0.0186 20-Sep K.LISSVDPQFLK.L "sp|Q9BVG4|PBDC1_HUMAN,tr|A6NDF3|A6NDF3_HUMAN" 2 1245.6969 8.08 13069 16531 2 1245.698905 623.8557 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 5.84 3345.2 - 3.20E+06 - - - 1.6184 - 1.439 0.329 - 177.4 1 2 0 0.002 11 0 0 0 2.38E+07 2.94E+06 - - - 2.4549 0.992 230117_WJC_METTL3_WT_vs_EV_F02.16535.16535.2 0.0487 14-Jul R.WPVDLVEK.L "sp|P06737|PYGL_HUMAN,tr|E9PK47|E9PK47_HUMAN" 2 984.528 18.24 13073 16535 2 984.53157 493.2713 "Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL PE=1 SV=4" 4.37 3345.5 - 1.25E+06 - - - 3.5926 - 1.344 0.195 - 132 1 2 0 0.0035 8 0 0 0 1.18E+08 6.45E+06 - - - 1.3718 0.9761 230117_WJC_METTL3_WT_vs_EV_F02.16537.16537.2 1.27 16-Aug R.ALAYFEQLK.L "sp|O43592|XPOT_HUMAN,tr|F5GYW6|F5GYW6_HUMAN,tr|F8WDU6|F8WDU6_HUMAN" 3 1081.5808 4.64 13075 16537 2 1081.585545 541.7977 Exportin-T OS=Homo sapiens OX=9606 GN=XPOT PE=1 SV=2 6.05 3345.8 - 1.03E+06 - - - 4.3899 - 1.374 0.132 - 157.3 1 2 0 0.0047 9 0 0 0 5.27E+06 1.14E+06 - - - 0.9337 0.9647 230117_WJC_METTL3_WT_vs_EV_F02.16539.16539.2 0.358 18-Sep K.IIVAC[160.03]IETLR.K "sp|Q14008|CKAP5_HUMAN,tr|E9PQH5|E9PQH5_HUMAN" 2 1186.6744 2.88 13077 16539 2 1186.680367 594.3445 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 5.99 3346 - 619061 - - - 5.0452 - 1.496 0.109 - 202.8 1 2 0 0.006 10 0 0 0 5.06E+06 1.76E+06 - - - 0.9685 0.997 230117_WJC_METTL3_WT_vs_EV_F02.16541.16541.2 0.261 14-Jun K.SIILEGFK.S sp|O95347|SMC2_HUMAN 1 905.5222 0.15 13079 16541 2 905.524557 453.7684 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 5.72 3346.3 - 438697 - - - 2.5819 - 1.23 0.273 - 83.5 1 2 0 0.0023 8 0 0 0 2.54E+06 1.68E+07 - - - 1.681 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.16550.16550.2 0.0617 14-Sep R.IGVDLIMK.T "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 887.515 1.19 13086 16550 2 887.517519 444.7648 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.84 3347.4 - 1.60E+06 - - - 2.8101 - 1.397 0.361 - 155.3 1 2 0 0.0025 8 0 0 0 3.34E+07 2.81E+07 - - - 2.7149 0.985 230117_WJC_METTL3_WT_vs_EV_F02.16551.16551.2 0.507 12-Jun K.NLFELAR.Q "sp|Q9UN37|VPS4A_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 2 861.4709 7.03 13087 16551 2 861.472738 431.7427 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 6 3347.5 - 1.24E+06 - - - 2.1893 - 1.058 0.148 - 128.6 1 2 0 0.0019 7 0 0 0 4.64E+07 6.60E+06 - - - 0.3122 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.16553.16553.2 0.037 12-Aug K.VFDLLNR.K "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|H0Y8H2|H0Y8H2_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 875.4865 1.27 13089 16553 2 875.486395 438.7505 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 5.81 3347.7 - 915847 - - - -0.1222 - 1.659 0.172 - 272.8 1 2 0 -0.0001 7 0 0 0 1.99E+07 1.56E+07 - - - 1.9153 0.9895 230117_WJC_METTL3_WT_vs_EV_F02.16554.16554.2 0.128 16-Jun K.VYLGDIPLK[136.11].T "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1024.6048 1.25 13090 16554 2 1024.6053 513.3097 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.81 3347.8 - 870404 - - - 0.4558 - 1.151 0.151 - 121.3 1 2 0 0.0005 9 0 0 0 3.42E+07 2.73E+07 - - - 0.563 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.16555.16555.2 0.000322 16-Oct R.LLQSLLDTR.C sp|Q13045|FLII_HUMAN 1 1057.6132 1.23 13091 16555 2 1057.616102 529.8139 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3347.9 - 837145 - - - 2.7827 - 1.863 0.43 - 343.6 1 2 0 0.0029 9 0 0 0 2.04E+07 1.66E+07 - - - 4.0161 1 230117_WJC_METTL3_WT_vs_EV_F02.16557.16557.2 0.000877 20-Nov K.NALESYAFNMK.S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1286.5965 295.37 13093 16557 2 1286.600131 644.3055 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3348.1 - 322467 - - - 2.8043 - 2.395 0.464 - 484.7 1 2 0 0.0036 11 0 0 0 2.62E+07 8.86E+04 - - - 4.8297 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.16574.16574.2 0.0125 16-Aug K.FGLFTPGSR.L "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 980.508 0.64 13105 16574 2 980.508043 491.2613 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 9.75 3350.1 - 7.07E+06 - - - 0.0785 - 1.797 0.362 - 236.2 1 2 0 0.0001 9 0 0 0 1.20E+08 1.87E+08 - - - 3.4104 0.999 230117_WJC_METTL3_WT_vs_EV_F02.16577.16577.2 0.0169 20-Sep K.ALTLIAGSPLK.L "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1082.6699 0.05 13107 16577 2 1082.669586 542.3422 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 8.8 3350.4 - 1.41E+06 - - - -0.3325 - 1.98 0.298 - 218.7 1 2 0 -0.0004 11 0 0 0 1.69E+07 3.31E+08 - - - 3.0899 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.16587.16587.2 5.33E-06 22-Nov K.VFGAAPLENVVR.K "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 1270.7034 5.95 13114 16587 2 1270.703926 636.359 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 5.97 3351.6 - 1.81E+06 - - - 0.4368 - 2.084 0.457 - 406.1 1 2 0 0.0006 12 0 0 0 1.18E+08 1.98E+07 - - - 4.3483 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.16597.16597.2 1.1 14-Aug R.DAFLTLAR.D "sp|Q92793|CBP_HUMAN,sp|Q09472|EP300_HUMAN,tr|A0A669KB12|A0A669KB12_HUMAN" 3 905.4971 1.42 13121 16597 2 905.499919 453.7558 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 5.84 3352.9 - 1.29E+06 - - - 3.1497 - 1.699 0.216 - 250.3 1 2 0 0.0029 8 0 0 0 2.15E+07 1.52E+07 - - - 2.2341 0.9846 230117_WJC_METTL3_WT_vs_EV_F02.16603.16603.2 0.205 12-Jul R.DLIDYVR.Y "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 892.4654 2.16 13123 16603 2 892.46481 447.24 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.21 3353.6 - 1.21E+06 - - - -0.6969 - 1.271 0.126 - 212.5 1 2 0 -0.0006 7 0 0 0 6.90E+07 3.19E+07 - - - 0.7313 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.16613.16613.2 0.0147 24-Dec K.VLIIGGGDGGVLR.E "sp|P19623|SPEE_HUMAN,tr|K7ESL0|K7ESL0_HUMAN" 2 1224.719 14.9 13128 16613 2 1224.716589 613.3668 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.81 3354.9 - 2.86E+06 - - - -1.9858 - 1.919 0.419 - 417.6 1 2 0 -0.0024 13 0 0 0 9.69E+07 6.51E+06 - - - 3.8078 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.16623.16623.2 0.00413 14-Oct R.IPQLLLER[166.11].Y "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 990.6101 1.04 13131 16623 2 990.607607 496.3123 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 6 3356.3 - 4.92E+06 - - - -2.553 - 1.952 0.353 - 508.6 1 2 0 -0.0025 8 0 0 0 1.42E+08 1.36E+08 - - - 3.6647 0.9964 230117_WJC_METTL3_WT_vs_EV_F02.16643.16643.2 0.00219 18-Sep R.LYLINSPVVR.A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1172.6917 1.53 13136 16643 2 1172.696687 587.3531 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3359 - 1.77E+06 - - - 4.2151 - 1.76 0.257 - 345.2 1 2 0 0.0049 10 0 0 0 5.22E+08 3.40E+08 - - - 2.5156 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.16650.16650.2 0.00278 18-Jul K.IFFAGDTIPK[136.11].S "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 5 1115.6106 2.58 13137 16650 2 1115.612819 558.8126 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.84 3360.1 - 707182 - - - 1.9469 - 1.655 0.423 - 64 2 2 0 0.0022 10 0 0 0 8.14E+07 3.15E+07 - - - 3.4364 0.9855 230117_WJC_METTL3_WT_vs_EV_F02.16653.16653.2 0.000408 18-Oct R.LYLINSPVVR[166.11].A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1182.7 1.53 13138 16653 2 1182.694521 592.3573 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3360.5 - 2.01E+06 - - - -4.6445 - 2.04 0.281 - 374.3 1 2 0 -0.0055 10 0 0 0 5.22E+08 3.40E+08 - - - 3.1048 0.8869 230117_WJC_METTL3_WT_vs_EV_F02.16660.16660.2 0.136 12-Jun K.ELLIFNK[136.11].Q "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 883.5259 1.07 13140 16660 2 883.524176 442.7702 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.1 3361.4 - 2.26E+06 - - - -1.8992 - 1.28 0.002 - 131.9 1 2 0 -0.0017 7 0 0 0 5.95E+08 5.58E+08 - - - -0.1626 1 230117_WJC_METTL3_WT_vs_EV_F02.16671.16671.2 0.00105 18-Dec R.VAAAVDLIIK.S "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1011.6328 2.63 13144 16671 2 1011.625221 506.8237 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3362.7 - 3.75E+06 - - - -7.5235 - 2.523 0.457 - 443.9 1 2 0 -0.0076 10 0 0 0 1.28E+08 4.86E+07 - - - 4.9972 0.99 230117_WJC_METTL3_WT_vs_EV_F02.16674.16674.2 0.148 14-Aug R.VAFTLLEK.V "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 4 919.5379 7.02 13147 16674 2 919.535096 460.7762 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 5.97 3363.1 - 2.69E+06 - - - -3.0156 - 1.581 0.261 - 201.5 1 2 0 -0.0028 8 0 0 0 8.55E+07 1.22E+07 - - - 2.3494 0.9957 230117_WJC_METTL3_WT_vs_EV_F02.16677.16677.2 1.11 14-Sep K.IPLGLDLK.N "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 867.543 1.48 13148 16677 2 867.54443 434.7788 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.84 3363.5 - 0 - - - 1.7014 - 1.714 0.061 - 306.2 1 2 0 0.0015 8 0 0 0 1.33E+08 9.03E+07 - - - 1.1162 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.16678.16678.2 0.000397 18-Sep R.GTPLISPLIK.W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1037.6485 1.66 13149 16678 2 1037.645573 519.8315 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3363.6 - 2.35E+06 - - - -2.8035 - 1.61 0.439 - 321.1 1 2 0 -0.0029 10 0 0 0 2.54E+08 1.53E+08 - - - 3.6119 0.9732 230117_WJC_METTL3_WT_vs_EV_F02.16697.16697.2 0.584 16-Jun K.GSLLPTSPR[166.11].L "tr|H7C179|H7C179_HUMAN,tr|H7C128|H7C128_HUMAN,tr|H7C127|H7C127_HUMAN" 3 936.5268 1.57 13154 16697 2 936.526356 469.2707 Bromodomain-containing protein 8 (Fragment) OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=1 9.75 3366.2 - 1.19E+06 - - - -0.4752 - 1.426 0.066 - 73.6 5 2 0 -0.0004 9 0 0 0 1.96E+08 1.25E+08 - - - 0.2428 1 230117_WJC_METTL3_WT_vs_EV_F02.16698.16698.2 2.77E-07 22-Dec R.GYISPYFINTSK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1388.6976 3.04 13155 16698 2 1388.698246 695.3561 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3366.4 - 2.39E+06 - - - 0.4529 - 2.442 0.485 - 542.7 1 2 0 0.0006 12 0 0 0 6.06E+07 2.00E+07 - - - 4.9722 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.16699.16699.2 0.000489 18-Sep R.GTPLISPLIK[136.11].W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1045.6627 1.66 13156 16699 2 1045.660151 523.8386 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3366.4 - 6.98E+06 - - - -2.4205 - 1.7 0.462 - 280.3 1 2 0 -0.0025 10 0 0 0 2.54E+08 1.53E+08 - - - 3.9337 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.16700.16700.2 0.0081 18-Dec R.YGLAAAVFTR[166.11].D sp|P30837|AL1B1_HUMAN 1 1077.5847 5.37 13157 16700 2 1077.582153 539.7996 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 8.75 3366.6 - 993894 - - - -2.3172 - 2.335 0.359 - 441.7 1 2 0 -0.0025 10 0 0 0 5.22E+07 9.72E+06 - - - 4.0588 0.995 230117_WJC_METTL3_WT_vs_EV_F02.16702.16702.2 0.141 14-Jul K.GYGFGLIK.L "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 853.4698 1.38 13158 16702 2 853.468963 427.7422 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 3366.8 - 9.68E+06 - - - -0.969 - 1.084 0.336 - 130.9 1 2 0 -0.0008 8 0 0 0 7.04E+08 5.11E+08 - - - 1.7657 0.9906 230117_WJC_METTL3_WT_vs_EV_F02.16705.16705.2 2.16 16-Jul K.GSLLPTSPR.L "tr|H7C179|H7C179_HUMAN,tr|H7C128|H7C128_HUMAN,tr|H7C127|H7C127_HUMAN" 3 926.5185 1.43 13159 16705 2 926.520326 464.2665 Bromodomain-containing protein 8 (Fragment) OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=1 9.75 3367.2 - 1.81E+06 - - - 1.9374 - 1.287 0.109 - 144.7 1 2 0 0.0018 9 0 0 0 1.97E+08 1.38E+08 - - - 0.5755 1 230117_WJC_METTL3_WT_vs_EV_F02.16708.16708.2 6.84E-05 20-Nov R.FGGLVLSPVGK.Q sp|Q9UJK0|TSR3_HUMAN 1 1072.6281 1.46 13160 16708 2 1072.622308 537.3213 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.75 3367.6 - 1.08E+06 - - - -5.3821 - 2.194 0.511 - 387.5 1 2 0 -0.0058 11 0 0 0 6.00E+07 4.11E+07 - - - 4.939 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.16714.16714.2 0.182 14-Aug R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 7060.9 13162 16714 2 1000.559656 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3368.4 - 1.89E+09 - - - 0.3228 - 1.95 0.283 - 234.1 1 2 0 0.0003 8 0 0 0 5.08E+11 7.19E+07 - - - 3.1453 0.9935 230117_WJC_METTL3_WT_vs_EV_F02.16720.16720.2 0.00712 12-Jul K.FTVPMLK.E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 834.4673 0.87 13163 16720 2 834.466579 418.2409 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3369.3 - 1.41E+06 - - - -0.9203 - 1.442 0.178 - 159.6 1 2 0 -0.0008 7 0 0 0 1.10E+08 1.26E+08 - - - 1.5153 1 230117_WJC_METTL3_WT_vs_EV_F02.16721.16721.2 0.000492 18-Nov R.YGLAAAVFTR.D sp|P30837|AL1B1_HUMAN 1 1067.5764 5.4 13164 16721 2 1067.576552 534.7955 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 8.75 3369.5 - 1.38E+06 - - - 0.1611 - 2.287 0.522 - 347.4 1 2 0 0.0002 10 0 0 0 5.44E+07 1.01E+07 - - - 5.2055 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.16728.16728.2 0.147 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.15 13168 16728 2 1235.758324 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3370.3 - 1.21E+06 - - - -1.4841 - 1.893 0.349 - 257.5 1 2 0 -0.0018 11 0 0 0 1.01E+08 8.82E+07 - - - 3.3445 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.16729.16729.2 0.22 20-Oct K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.12 13169 16729 2 1245.768218 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3370.5 - 953982 - - - -0.1686 - 2.057 0.396 - 305.9 1 2 0 -0.0002 11 0 0 0 9.98E+07 8.89E+07 - - - 3.9169 1 230117_WJC_METTL3_WT_vs_EV_F02.16733.16733.2 0.000162 13/20 R.FGGLVLSPVGK[136.11].Q sp|Q9UJK0|TSR3_HUMAN 1 1080.6423 1.5 13170 16733 2 1080.64524 541.3284 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.75 3371 - 807253 - - - 2.7382 - 2.339 0.497 - 504.5 1 2 0 0.003 11 0 0 0 5.99E+07 3.99E+07 - - - 5.0096 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.16739.16739.2 0.0118 16-Aug R.GLFTGLTPR[166.11].L "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 970.5475 1.18 13174 16739 2 970.546343 486.281 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3371.8 - 795919 - - - -1.2292 - 1.788 0.24 - 175.3 1 2 0 -0.0012 9 0 0 0 4.02E+07 3.41E+07 - - - 2.4944 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.16744.16744.2 0.000653 12-Jul R.FFLEYDR.L "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 988.4654 2.79 13177 16744 2 988.467704 495.24 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 4.37 3372.5 - 1.23E+06 - - - 2.2985 - 1.436 0.403 - 163.8 1 2 0 0.0023 7 0 0 0 2.25E+07 8.07E+06 - - - 3.1634 0.998 230117_WJC_METTL3_WT_vs_EV_F02.16746.16746.2 0.193 16-Oct K.LLC[160.03]GLLAER[166.11].L sp|P14174|MIF_HUMAN 1 1053.588 0.92 13179 16746 2 1053.586642 527.8013 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3372.6 - 1.16E+07 - - - -1.3089 - 1.992 0.265 - 330 1 2 0 -0.0014 9 0 0 0 7.12E+08 7.73E+08 - - - 2.9916 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.16747.16747.2 0.0021 16-Oct K.LLC[160.03]GLLAER.L sp|P14174|MIF_HUMAN 1 1043.5798 0.92 13180 16747 2 1043.577726 522.7972 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3372.6 - 6.21E+06 - - - -1.9404 - 2.058 0.398 - 331.3 1 2 0 -0.002 9 0 0 0 7.15E+08 7.77E+08 - - - 4.068 0.9499 230117_WJC_METTL3_WT_vs_EV_F02.16748.16748.2 6.85E-05 20-Dec Q.WGTLTDC[160.03]VVMR.D "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 14 1336.6268 0.85 13181 16748 2 1336.625547 669.3207 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.83 3372.7 - 1.25E+06 - - - -0.921 - 2.078 0.475 - 450.7 1 1 0 -0.0012 11 0 0 0 1.37E+07 1.62E+07 - - - 4.5276 0.9722 230117_WJC_METTL3_WT_vs_EV_F02.16752.16752.2 0.029 14-Aug K.LGPLAFYK.G "sp|Q9UBX3|DIC_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 907.5167 1.71 13183 16752 2 907.520652 454.7656 Mitochondrial dicarboxylate carrier OS=Homo sapiens OX=9606 GN=SLC25A10 PE=1 SV=2 8.59 3373.3 - 1.51E+06 - - - 4.3107 - 1.517 0.065 - 147.9 1 2 0 0.0039 8 0 0 0 3.92E+07 2.29E+07 - - - 0.7767 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.16754.16754.2 0.0863 16-Aug R.GLFTGLTPR.L "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 960.5393 1.17 13184 16754 2 960.538645 481.2769 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3373.5 - 922095 - - - -0.6465 - 1.753 0.332 - 153.3 1 2 0 -0.0006 9 0 0 0 4.06E+07 3.47E+07 - - - 3.1169 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.16755.16755.2 0.0135 16-Aug R.YVANLFPYK[136.11].G "sp|Q15181|IPYR_HUMAN,sp|Q9H2U2|IPYR2_HUMAN,tr|D6RGV9|D6RGV9_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN,tr|D6RGI1|D6RGI1_HUMAN,tr|H0YAK2|H0YAK2_HUMAN" 7 1121.6001 2.74 13185 16755 2 1121.60039 561.8073 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 8.5 3373.6 - 590547 - - - 0.2746 - 1.436 0.306 - 178.6 1 2 0 0.0003 9 0 0 0 7.62E+07 2.79E+07 - - - 2.3479 0.9941 230117_WJC_METTL3_WT_vs_EV_F02.16760.16760.2 0.347 14-Jul R.QVFLATWK.D "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 991.5491 0 13188 16760 2 991.548852 496.7818 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.75 3374.2 - 817974 - - - -0.2521 - 1.244 0.211 - 137.2 1 2 0 -0.0003 8 0 0 0 1.50E+07 1.23E+10 - - - 1.2578 1 230117_WJC_METTL3_WT_vs_EV_F02.16761.16761.2 3.57E-05 18-Dec K.VYVIGSFVDK[136.11].S sp|Q7L0Y3|TM10C_HUMAN 1 1133.6212 0.74 13189 16761 2 1133.62128 567.8179 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3374.4 - 1.04E+06 - - - 0.0609 - 2.18 0.474 - 454.6 1 2 0 0.0001 10 0 0 0 2.48E+07 3.34E+07 - - - 4.7173 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16764.16764.2 0.0717 18-Nov K.VYVIGSFVDK.S sp|Q7L0Y3|TM10C_HUMAN 1 1125.607 0.74 13192 16764 2 1125.609793 563.8108 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3374.6 - 877397 - - - 2.4716 - 2.377 0.411 - 408.6 1 2 0 0.0028 10 0 0 0 2.48E+07 3.34E+07 - - - 4.4926 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.16769.16769.2 0.0127 12-Jul R.FVAELWK[136.11].D sp|P35580|MYH10_HUMAN 1 899.4996 0.75 13195 16769 2 899.49903 450.7571 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3375.4 - 1.62E+06 - - - -0.6782 - 1.492 0.304 - 152.7 1 2 0 -0.0006 7 0 0 0 5.05E+07 6.77E+07 - - - 2.5539 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.16770.16770.2 0.00876 14-Jul K.LGPLAFYK[136.11].G "sp|Q9UBX3|DIC_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 915.5309 1.77 13196 16770 2 915.531163 458.7727 Mitochondrial dicarboxylate carrier OS=Homo sapiens OX=9606 GN=SLC25A10 PE=1 SV=2 8.59 3375.5 - 1.07E+06 - - - 0.2436 - 1.259 0.275 - 108 1 2 0 0.0002 8 0 0 0 3.86E+07 2.18E+07 - - - 1.7667 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.16774.16774.2 0.019 12-Jul K.LMIWDTR.S "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 933.4742 1.45 13198 16774 2 933.474991 467.7444 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3375.9 - 3.85E+06 - - - 0.8227 - 1.426 0.389 - 272 1 2 0 0.0008 7 0 0 0 2.07E+08 1.43E+08 - - - 3.0383 0.9963 230117_WJC_METTL3_WT_vs_EV_F02.16776.16776.2 0.00809 18-Aug K.APGLGLVLER.V "sp|Q9Y606|TRUA_HUMAN,tr|G8JLB3|G8JLB3_HUMAN,tr|F5H1S9|F5H1S9_HUMAN" 3 1023.6077 1.85 13200 16776 2 1023.605763 512.8111 tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3 6.05 3376.1 - 1.28E+06 - - - -1.8728 - 1.609 0.309 - 106.1 1 2 0 -0.0019 10 0 0 0 2.88E+07 1.56E+07 - - - 2.6503 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.16778.16778.2 0.00747 22-Jul R.VLIGNVQPGILR.F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1277.782 2.99 13202 16778 2 1277.783445 639.8983 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3376.4 - 404938 - - - 1.1653 - 1.811 0.337 - 168.5 1 2 0 0.0015 12 0 0 0 6.12E+06 2.04E+06 - - - 3.0922 0.9387 230117_WJC_METTL3_WT_vs_EV_F02.16779.16779.2 2.98 20-Oct R.ALDEGDIALLK.T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1156.634 2.96 13203 16779 2 1156.638408 579.3243 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 3376.5 - 379307 - - - 3.8508 - 1.145 0.08 - 113.6 1 2 0 0.0045 11 0 0 0 1.30E+07 4.37E+06 - - - -0.0032 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.16784.16784.2 0.713 12-Jun R.FVAELWK.D sp|P35580|MYH10_HUMAN 1 891.4854 0.73 13206 16784 2 891.485781 446.75 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3377.1 - 2.07E+06 - - - 0.3825 - 1.309 0.295 - 107.6 1 2 0 0.0003 7 0 0 0 5.12E+07 6.97E+07 - - - 2.0729 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.16787.16787.2 0.487 14-Oct R.LGISSLIR.E sp|P35573|GDE_HUMAN 1 857.5335 0.74 13209 16787 2 857.533733 429.774 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3377.5 - 658356 - - - 0.3277 - 1.707 0.202 - 206.3 1 2 0 0.0003 8 0 0 0 4.10E+07 5.54E+07 - - - 2.1456 0.9677 230117_WJC_METTL3_WT_vs_EV_F02.16792.16792.2 1.01 12-Aug K.LDDLFLK.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 862.48 1 13212 16792 2 862.477674 432.2473 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3378.1 - 538811 - - - -2.7201 - 1.604 0.08 - 224 1 2 0 -0.0023 7 0 0 0 1.03E+08 1.04E+08 - - - 1.1283 0.999 230117_WJC_METTL3_WT_vs_EV_F02.16797.16797.2 0.221 12-Jul R.GFELTFK[136.11].T "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 848.4524 1.45 13217 16797 2 848.453211 425.2335 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3378.5 - 266131 - - - 1.0089 - 1.512 0.284 - 174.3 1 2 0 0.0009 7 0 0 0 5.45E+07 3.75E+07 - - - 2.4483 1 230117_WJC_METTL3_WT_vs_EV_F02.16799.16799.2 3.77E-06 20-Dec R.ALDEGDIALLK[136.11].T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1164.6482 2.96 13219 16799 2 1164.646492 583.3314 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 3378.8 - 116144 - - - -1.427 - 2.595 0.524 - 321.8 1 2 0 -0.0017 11 0 0 0 1.30E+07 4.37E+06 - - - 5.4904 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.16802.16802.2 0.176 18-Jul R.FGVITEVDIK.R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1119.6176 4.86 13220 16802 2 1119.6169 560.8161 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 4.37 3379.2 - 1.40E+06 - - - -0.6038 - 1.617 0.303 - 155.4 1 2 0 -0.0007 10 0 0 0 5.70E+07 1.17E+07 - - - 2.6202 0.9792 230117_WJC_METTL3_WT_vs_EV_F02.16804.16804.2 0.0522 16-Jun K.IDPEAFITR[166.11].H sp|Q92616|GCN1_HUMAN 1 1070.5636 1.2 13222 16804 2 1070.560811 536.2891 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3379.3 - 750411 - - - -2.5865 - 1.089 0.289 - 69.4 1 2 0 -0.0028 9 0 0 0 3.33E+07 2.79E+07 - - - 1.4213 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.16813.16813.2 4.20E-05 18-Nov R.FGVITEVDIK[136.11].R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1127.6318 4.85 13228 16813 2 1127.635301 564.8232 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 4.37 3380.3 - 1.33E+06 - - - 3.126 - 2.049 0.332 - 414.4 1 2 0 0.0035 10 0 0 0 5.69E+07 1.17E+07 - - - 3.4944 0.9697 230117_WJC_METTL3_WT_vs_EV_F02.16814.16814.2 0.00028 16-Nov K.PLALVEEIR.N "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1038.6073 1.82 13229 16814 2 1038.609954 520.3109 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 4.53 3380.5 - 549607 - - - 2.5111 - 2.107 0.414 - 328.1 1 1 0 0.0026 9 0 0 0 9.96E+06 5.49E+06 - - - 4.2541 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.16818.16818.2 0.0363 20-Sep R.ALAAQLPVLPR.S "sp|Q96GK7|FAH2A_HUMAN,tr|C9JGM0|C9JGM0_HUMAN" 2 1147.7077 3.47 13233 16818 2 1147.709846 574.8611 Fumarylacetoacetate hydrolase domain-containing protein 2A OS=Homo sapiens OX=9606 GN=FAHD2A PE=1 SV=1 9.79 3381 - 289499 - - - 1.8454 - 1.83 0.36 - 214.8 1 2 0 0.0021 11 0 0 0 5.98E+06 1.72E+06 - - - 3.3341 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.16823.16823.2 4.59 12-Aug K.LDDLFLK[136.11].R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 870.4942 1.03 13237 16823 2 870.495304 436.2544 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3381.6 - 7.83E+06 - - - 1.2453 - 1.933 0.126 - 207.5 1 2 0 0.0011 7 0 0 0 1.02E+08 9.84E+07 - - - 2.0596 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.16825.16825.2 0.0128 14-Sep K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 0.82 13239 16825 2 988.573318 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3381.8 - 3.24E+06 - - - 2.7838 - 1.898 0.38 - 372.1 1 2 0 0.0028 8 0 0 0 4.49E+09 5.49E+09 - - - 3.7794 0.9523 230117_WJC_METTL3_WT_vs_EV_F02.16826.16826.2 2.47 12-Jun R.LYEFIVR.H sp|Q13472|TOP3A_HUMAN 1 938.5226 1.22 13240 16826 2 938.525935 470.2686 DNA topoisomerase 3-alpha OS=Homo sapiens OX=9606 GN=TOP3A PE=1 SV=1 6 3381.8 - 1.03E+06 - - - 3.6035 - 1.24 0.046 - 93.5 1 2 0 0.0034 7 0 0 0 2.61E+07 2.13E+07 - - - 0.0613 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.16827.16827.2 0.000604 16-Sep K.FLGELYNYR[166.11].M sp|Q9HAU5|RENT2_HUMAN 1 1183.5901 0.71 13241 16827 2 1183.592144 592.8023 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 6 3382 - 513144 - - - 1.7024 - 1.65 0.383 - 246 1 2 0 0.002 9 0 0 0 5.10E+06 7.23E+06 - - - 3.318 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.16830.16830.2 0.117 20-Oct K.LLAAFPGVTPR.V "sp|Q9Y2I1|NISCH_HUMAN,tr|C9J715|C9J715_HUMAN" 2 1140.6655 3.49 13244 16830 2 1140.668759 571.34 Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3 9.75 3382.4 - 386996 - - - 2.8317 - 1.804 0.224 - 254.6 1 2 0 0.0032 11 0 0 0 1.06E+07 3.04E+06 - - - 2.2906 0.8812 230117_WJC_METTL3_WT_vs_EV_F02.16831.16831.2 5.13 14-May K.LEPDILLR[166.11].A "sp|Q01433|AMPD2_HUMAN,tr|A0A7P0TB79|A0A7P0TB79_HUMAN,tr|A0A590UK85|A0A590UK85_HUMAN,tr|A0A5F9UK94|A0A5F9UK94_HUMAN,tr|E9PJF6|E9PJF6_HUMAN,tr|A0A590UJX5|A0A590UJX5_HUMAN,tr|H0Y360|H0Y360_HUMAN,tr|A0A7P0Z4H6|A0A7P0Z4H6_HUMAN,tr|E9PIJ1|E9PIJ1_HUMAN,tr|H0YF16|H0YF16_HUMAN,tr|A0A804CCZ3|A0A804CCZ3_HUMAN" 11 977.5785 3.03 13245 16831 2 977.582661 489.7965 AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2 4.37 3382.5 - 185468 - - - 4.2544 - 1.132 0.098 - 41.1 9 2 0 0.0042 8 0 0 0 1.18E+07 3.89E+06 - - - -0.2888 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.16834.16834.2 0.00181 12-Jul K.LMIWDTR[166.11].S "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 943.4825 1.83 13247 16834 2 943.484342 472.7485 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3382.8 - 4.45E+06 - - - 1.9598 - 1.473 0.34 - 271.9 1 2 0 0.0018 7 0 0 0 2.04E+08 1.12E+08 - - - 2.7788 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.16836.16836.2 0.268 14-Jul R.ILELDQFK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1012.5684 1.08 13249 16836 2 1012.570925 507.2915 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3383 - 1.63E+07 - - - 2.4472 - 1.379 0.308 - 115.4 1 2 0 0.0025 8 0 0 0 2.63E+08 2.43E+08 - - - 2.2843 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.16837.16837.2 0.489 14-Aug R.ILELDQFK.G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1004.5542 1.02 13250 16837 2 1004.558698 503.2844 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3383.1 - 1.46E+07 - - - 4.4308 - 1.801 0.266 - 169 1 2 0 0.0044 8 0 0 0 2.46E+08 2.42E+08 - - - 2.7787 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.16838.16838.2 1.52 14-Aug R.VWDISGLR[166.11].K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 954.5162 3.1 13251 16838 2 954.518091 478.2654 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3383.2 - 458685 - - - 1.9434 - 1.618 0.14 - 161.8 1 2 0 0.0019 8 0 0 0 7.61E+07 2.46E+07 - - - 1.5257 1 230117_WJC_METTL3_WT_vs_EV_F02.16840.16840.2 6.31E-06 18-Oct K.IVAFENAFER.L sp|O60763|USO1_HUMAN 1 1194.6033 0.94 13253 16840 2 1194.605729 598.3089 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 3383.4 - 225463 - - - 2.0141 - 2.028 0.522 - 259.2 1 2 0 0.0024 10 0 0 0 6.74E+06 7.18E+06 - - - 4.8693 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.16845.16845.2 0.126 14-Jul K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 0.82 13256 16845 2 998.580907 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3383.9 - 2.93E+07 - - - 2.0739 - 1.45 0.284 - 223.3 1 2 0 0.0021 8 0 0 0 4.49E+09 5.49E+09 - - - 2.2586 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16852.16852.2 1.66E-06 16-Oct R.YVANLFPYK.G "sp|Q15181|IPYR_HUMAN,sp|Q9H2U2|IPYR2_HUMAN,tr|D6RGV9|D6RGV9_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN,tr|D6RGI1|D6RGI1_HUMAN,tr|H0YAK2|H0YAK2_HUMAN" 7 1113.5859 3 13261 16852 2 1113.588951 557.8002 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 8.5 3384.7 - 2.64E+06 - - - 2.756 - 1.72 0.521 - 291.1 1 2 0 0.0031 9 0 0 0 3.15E+07 1.05E+07 - - - 4.4571 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.16855.16855.2 0.000158 18-Oct K.IVAFENAFER[166.11].L sp|O60763|USO1_HUMAN 1 1204.6116 0.94 13264 16855 2 1204.615158 603.3131 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 3385.1 - 562214 - - - 2.9595 - 1.553 0.508 - 228.5 1 2 0 0.0036 10 0 0 0 6.74E+06 7.18E+06 - - - 4.0207 0.99 230117_WJC_METTL3_WT_vs_EV_F02.16856.16856.2 0.0329 14-Jul K.LEPDILLR.A "sp|Q01433|AMPD2_HUMAN,tr|A0A7P0TB79|A0A7P0TB79_HUMAN,tr|A0A590UK85|A0A590UK85_HUMAN,tr|A0A5F9UK94|A0A5F9UK94_HUMAN,tr|E9PJF6|E9PJF6_HUMAN,tr|A0A590UJX5|A0A590UJX5_HUMAN,tr|H0Y360|H0Y360_HUMAN,tr|A0A7P0Z4H6|A0A7P0Z4H6_HUMAN,tr|E9PIJ1|E9PIJ1_HUMAN,tr|H0YF16|H0YF16_HUMAN,tr|A0A804CCZ3|A0A804CCZ3_HUMAN" 11 967.5702 3.03 13265 16856 2 967.574747 484.7924 AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2 4.37 3385.2 - 428349 - - - 4.6663 - 1.481 0.215 - 137 1 2 0 0.0045 8 0 0 0 1.18E+07 3.89E+06 - - - 1.812 0.9803 230117_WJC_METTL3_WT_vs_EV_F02.16861.16861.2 0.0183 14-Aug R.VWDISGLR.K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 944.508 3.1 13268 16861 2 944.512706 473.2613 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3385.9 - 4.45E+06 - - - 5.0185 - 1.735 0.098 - 270.8 1 2 0 0.0047 8 0 0 0 7.61E+07 2.46E+07 - - - 1.4252 1 230117_WJC_METTL3_WT_vs_EV_F02.16865.16865.2 4.87E-06 18-Nov K.C[160.03]LEPTVALLR[166.11].W "sp|Q8TCG1|CIP2A_HUMAN,tr|A0A087X211|A0A087X211_HUMAN" 2 1180.6514 2.02 13272 16865 2 1180.653135 591.333 Protein CIP2A OS=Homo sapiens OX=9606 GN=CIP2A PE=1 SV=2 5.99 3386.3 - 487822 - - - 1.5119 - 2.168 0.507 - 422.3 1 2 0 0.0018 10 0 0 0 1.58E+07 7.81E+06 - - - 4.9451 0.9925 230117_WJC_METTL3_WT_vs_EV_F02.16867.16867.2 0.0589 12-May K.FIDPFC[160.03]K.L sp|Q14684|RRP1B_HUMAN 1 925.4368 3.56 13273 16867 2 925.438752 463.7257 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.83 3386.5 - 1.35E+06 - - - 2.1363 - 0.992 0.24 - 77.6 1 2 0 0.002 7 0 0 0 3.45E+07 9.70E+06 - - - 0.7876 0.9924 230117_WJC_METTL3_WT_vs_EV_F02.16871.16871.2 3.16 14-Jul R.DILLQGLK[136.11].A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 906.563 0.82 13276 16871 2 906.562802 454.2888 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3386.9 - 2.01E+06 - - - -0.1831 - 1.402 0.131 - 139.9 1 2 0 -0.0002 8 0 0 0 2.03E+07 2.49E+07 - - - 1.0276 0.9941 230117_WJC_METTL3_WT_vs_EV_F02.16872.16872.2 0.125 12-Jun R.GFELTFK.T "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 840.4382 1.5 13277 16872 2 840.437703 421.2264 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3387 - 1.94E+06 - - - -0.5378 - 1.104 0.276 - 118.7 1 2 0 -0.0005 7 0 0 0 5.45E+07 3.63E+07 - - - 1.3929 0.9697 230117_WJC_METTL3_WT_vs_EV_F02.16874.16874.2 0.404 22-Sep -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 1.49 13279 16874 2 1306.766238 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3387.2 - 1.04E+06 - - - -1.5626 - 1.455 0.082 - 139.3 1 2 0 -0.002 12 0 0 0 3.04E+07 2.04E+07 - - - 0.6327 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.16875.16875.2 0.0142 18-Oct R.LLLNNDNLLR[166.11].E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1206.696 1.55 13280 16875 2 1206.696962 604.3553 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3387.4 - 789556 - - - 0.8047 - 2.055 0.259 - 270.1 1 2 0 0.001 10 0 0 0 3.41E+08 2.20E+08 - - - 2.9642 0.9945 230117_WJC_METTL3_WT_vs_EV_F02.16876.16876.2 0.117 22-Aug -.MVPPVQVSPLIK[136.11].L sp|P56385|ATP5I_HUMAN 1 1314.7825 1.48 13281 16876 2 1314.780748 658.3985 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3387.5 - 625685 - - - -1.3173 - 1.467 0.249 - 111.1 1 2 0 -0.0017 12 0 0 0 2.97E+07 2.01E+07 - - - 1.8879 0.9955 230117_WJC_METTL3_WT_vs_EV_F02.16878.16878.2 0.005 20-Jul R.LYPEGLAQLAR.A "sp|P61421|VA0D1_HUMAN,tr|J3QL14|J3QL14_HUMAN,tr|F5GYQ1|F5GYQ1_HUMAN,tr|R4GN72|R4GN72_HUMAN" 4 1229.6768 1.39 13283 16878 2 1229.677008 615.8457 V-type proton ATPase subunit d 1 OS=Homo sapiens OX=9606 GN=ATP6V0D1 PE=1 SV=1 6 3387.8 - 368446 - - - 0.1513 - 1.405 0.182 - 147.1 1 2 0 0.0002 11 0 0 0 1.48E+07 1.06E+07 - - - 1.3051 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.16884.16884.2 0.000507 18-Oct R.LLLNNDNLLR.E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1196.6877 1.55 13288 16884 2 1196.688409 599.3511 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3388.3 - 1.48E+06 - - - 0.5749 - 2.06 0.477 - 313.2 1 2 0 0.0007 10 0 0 0 3.41E+08 2.20E+08 - - - 4.5812 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.16886.16886.2 0.0288 14-Aug R.LELSVLYK.E "sp|Q96FW1|OTUB1_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 5 963.5641 2.01 13290 16886 2 963.565714 482.7893 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 6 3388.6 - 790056 - - - 1.6916 - 1.924 0.23 - 169.6 1 2 0 0.0016 8 0 0 0 2.20E+07 1.09E+07 - - - 2.7129 1 230117_WJC_METTL3_WT_vs_EV_F02.16889.16889.2 3.21E-05 20-Nov R.FDLALAATEAR.Q sp|Q6PD62|CTR9_HUMAN 1 1176.6139 1.78 13293 16889 2 1176.615762 589.3142 RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1 4.37 3388.9 - 360939 - - - 1.5927 - 2.462 0.512 - 398.1 1 2 0 0.0019 11 0 0 0 9.06E+06 5.08E+06 - - - 5.2594 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.16892.16892.2 0.0266 14-Jul K.YVVGLIIK[136.11].T "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 911.5935 1.37 13294 16892 2 911.593523 456.804 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3389.2 - 3.31E+06 - - - -0.0186 - 1.381 0.291 - 150.7 1 2 0 0 8 0 0 0 4.82E+07 3.53E+07 - - - 2.1639 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.16893.16893.2 0.252 16-Jul R.EPGEFALLR[166.11].S sp|O43505|B4GA1_HUMAN 1 1040.553 3.47 13295 16893 2 1040.552405 521.2838 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 4.53 3389.3 - 2.43E+06 - - - -0.5862 - 1.555 0.313 - 181.7 1 2 0 -0.0006 9 0 0 0 4.50E+08 1.30E+08 - - - 2.6298 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.16894.16894.2 0.141 14-Sep R.DILLQGLK.A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 898.5488 0.81 13296 16894 2 898.548236 450.2817 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3389.4 - 3.80E+06 - - - -0.5921 - 1.641 0.17 - 260.3 1 2 0 -0.0005 8 0 0 0 2.03E+07 2.50E+07 - - - 1.7903 0.9219 230117_WJC_METTL3_WT_vs_EV_F02.16895.16895.2 2.83 14-Jun K.LPLDVLGR[166.11].V "sp|Q9UBC2|EP15R_HUMAN,tr|M0R2S2|M0R2S2_HUMAN,tr|M0R165|M0R165_HUMAN" 3 891.5417 3.46 13297 16895 2 891.540365 446.7781 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 5.84 3389.4 - 2.00E+06 - - - -1.5221 - 1.085 0.089 - 97.6 1 2 0 -0.0014 8 0 0 0 6.09E+07 1.76E+07 - - - -0.056 0.9957 230117_WJC_METTL3_WT_vs_EV_F02.16896.16896.2 0.0421 16-Aug K.IDPEAFITR.H sp|Q92616|GCN1_HUMAN 1 1060.5553 1.2 13298 16896 2 1060.552622 531.2849 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3389.5 - 1.86E+06 - - - -2.5345 - 1.582 0.355 - 224.5 1 2 0 -0.0027 9 0 0 0 3.37E+07 2.80E+07 - - - 2.9892 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.16899.16899.2 0.167 14-Aug R.LELSVLYK[136.11].E "sp|Q96FW1|OTUB1_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 5 971.5783 2.17 13301 16899 2 971.58062 486.7964 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 6 3389.9 - 1.36E+06 - - - 2.4043 - 1.792 0.147 - 145 1 2 0 0.0023 8 0 0 0 2.38E+07 1.09E+07 - - - 1.8853 0.993 230117_WJC_METTL3_WT_vs_EV_F02.16900.16900.2 0.0763 18-Oct K.IEDMAVSLIR[166.11].E sp|Q15776|ZKSC8_HUMAN 1 1155.6197 1.06 13302 16900 2 1155.614994 578.8171 Zinc finger protein with KRAB and SCAN domains 8 OS=Homo sapiens OX=9606 GN=ZKSCAN8 PE=1 SV=2 4.37 3390.1 - 678747 - - - -4.0853 - 2.001 0.367 - 226 1 2 0 -0.0047 10 0 0 0 5.92E+06 5.59E+06 - - - 3.6864 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.16902.16902.2 0.00379 18-Jul K.AVFVPDIYSR.T sp|O94874|UFL1_HUMAN 1 1165.6132 1.63 13304 16902 2 1165.611483 583.8139 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.88 3390.3 - 356310 - - - -1.4379 - 1.742 0.342 - 125.8 1 2 0 -0.0017 10 0 0 0 1.05E+07 6.43E+06 - - - 3.1158 0.9964 230117_WJC_METTL3_WT_vs_EV_F02.16905.16905.2 0.0401 14-Aug K.YVVGLIIK.T "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 903.5793 1.37 13305 16905 2 903.5785 452.7969 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3390.7 - 3.66E+06 - - - -0.9296 - 1.417 0.264 - 181.3 1 2 0 -0.0008 8 0 0 0 4.82E+07 3.53E+07 - - - 2.0418 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.16906.16906.2 0.00388 22-Dec K.ALLTPVAIAAGR.K sp|P00390|GSHR_HUMAN 1 1151.7026 3.33 13306 16906 2 1151.704861 576.8586 "Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2" 9.79 3390.8 - 874226 - - - 1.9258 - 2.404 0.358 - 428.6 1 2 0 0.0022 12 0 0 0 4.95E+07 1.49E+07 - - - 3.9924 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.16909.16909.2 4.41E-05 20-Oct R.FDLALAATEAR[166.11].Q sp|Q6PD62|CTR9_HUMAN 1 1186.6222 1.78 13309 16909 2 1186.625566 594.3184 RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1 4.37 3391.2 - 369754 - - - 2.872 - 2.135 0.436 - 255.2 1 2 0 0.0034 11 0 0 0 9.06E+06 5.08E+06 - - - 4.3121 0.994 230117_WJC_METTL3_WT_vs_EV_F02.16915.16915.2 0.0279 16-May K.LFSELPLAK.K "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1016.5906 1.23 13313 16915 2 1016.590867 509.3026 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 6 3391.9 - 4.68E+06 - - - 0.2302 - 1.087 0.239 - 71 1 2 0 0.0002 9 0 0 0 1.58E+08 1.28E+08 - - - 1.0475 0.9874 230117_WJC_METTL3_WT_vs_EV_F02.16920.16920.2 0.614 14-Jun R.LLEPFEVR[166.11].T sp|Q8WUY1|THEM6_HUMAN 1 1011.5629 18.57 13316 16920 2 1011.56339 506.7887 Protein THEM6 OS=Homo sapiens OX=9606 GN=THEM6 PE=1 SV=2 4.53 3392.4 - 834861 - - - 0.5319 - 1.075 0.156 - 98.6 1 2 0 0.0005 8 0 0 0 2.77E+09 1.49E+08 - - - 0.4112 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.16922.16922.2 4.66E-05 24-Aug R.ILGVGPDDPDLVR.A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1364.73 2.67 13318 16922 2 1364.7315 683.3723 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3392.7 - 0 - - - 1.1138 - 1.612 0.462 - 130.3 1 2 0 0.0015 13 0 0 0 6.00E+06 2.25E+06 - - - 3.6783 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.16926.16926.2 0.0217 13/18 R.ALEAELAALR[166.11].Q sp|Q16352|AINX_HUMAN 1 1065.6058 4.75 13320 16926 2 1065.606913 533.8102 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.53 3393.2 - 3.51E+06 - - - 1.0642 - 2.113 0.269 - 771.9 1 2 0 0.0011 10 0 0 0 2.22E+08 4.67E+07 - - - 3.1157 0.9963 230117_WJC_METTL3_WT_vs_EV_F02.16928.16928.2 0.0356 16-Aug R.LLVAVLTSR[166.11].A "sp|Q9P2E5|CHPF2_HUMAN,tr|G5E9W2|G5E9W2_HUMAN,tr|C9JZF7|C9JZF7_HUMAN" 3 980.6258 1.15 13322 16928 2 980.629968 491.3202 Chondroitin sulfate glucuronyltransferase OS=Homo sapiens OX=9606 GN=CHPF2 PE=2 SV=2 9.75 3393.5 - 617351 - - - 4.2646 - 1.63 0.281 - 130.5 1 2 0 0.0042 9 0 0 0 5.05E+06 4.38E+06 - - - 2.5286 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.16929.16929.2 0.00104 24-Oct R.ILGVGPDDPDLVR[166.11].A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1374.7383 2.61 13323 16929 2 1374.741767 688.3764 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3393.6 - 382942 - - - 2.5583 - 1.735 0.381 - 243 1 2 0 0.0035 13 0 0 0 5.87E+06 2.25E+06 - - - 3.2681 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.16931.16931.2 7.83E-06 26-Aug R.EAGNINQSLLTLGR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1494.803 0.07 13325 16931 2 1494.804148 748.4088 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.1 3393.9 - 174988 - - - 0.784 - 2.007 0.432 - 162.1 1 2 0 0.0012 14 0 0 0 1.30E+05 1.85E+06 - - - 3.9796 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.16935.16935.2 0.174 12-Aug R.LLQLWEK[136.11].N "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 936.5524 1.31 13327 16935 2 936.554412 469.2835 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 6 3394.4 - 2.25E+06 - - - 2.1451 - 1.647 0.231 - 184.8 1 2 0 0.002 7 0 0 0 8.03E+07 6.14E+07 - - - 2.3275 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.16940.16940.2 0.00852 14-Jul R.LMGDYLLR.G "sp|O60232|ZNRD2_HUMAN,tr|H0YEK1|H0YEK1_HUMAN,tr|E9PK41|E9PK41_HUMAN,tr|H0YEB6|H0YEB6_HUMAN" 4 979.5161 1.78 13332 16940 2 979.520118 490.7653 Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1 5.84 3394.9 - 693826 - - - 4.1143 - 1.529 0.333 - 118 1 2 0 0.004 8 0 0 0 3.50E+07 1.96E+07 - - - 2.7799 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.16941.16941.2 0.0518 18-Aug K.AVFVPDIYSR[166.11].T sp|O94874|UFL1_HUMAN 1 1175.6214 1.64 13333 16941 2 1175.624456 588.818 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.88 3395.1 - 289131 - - - 2.5748 - 1.522 0.328 - 233.8 1 2 0 0.003 10 0 0 0 1.05E+07 6.38E+06 - - - 2.6351 0.9173 230117_WJC_METTL3_WT_vs_EV_F02.16942.16942.2 5.83 12-Jun K.GIGEFFR[166.11].L "sp|Q15004|PAF15_HUMAN,tr|H0YMA4|H0YMA4_HUMAN,tr|A0A0U1RQM0|A0A0U1RQM0_HUMAN,tr|H0YKX3|H0YKX3_HUMAN" 4 834.4264 1.54 13334 16942 2 834.427986 418.2205 PCNA-associated factor OS=Homo sapiens OX=9606 GN=PCLAF PE=1 SV=1 6 3395.2 - 254186 - - - 1.951 - 0.826 0.094 - 91.2 1 2 0 0.0016 7 0 0 0 2.03E+07 1.31E+07 - - - -0.8709 0.928 230117_WJC_METTL3_WT_vs_EV_F02.16950.16950.2 0.00065 22-Jun R.IINEPTAAAIAY.G "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 16 1245.6605 - 13340 16950 2 1245.664222 623.8375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4 3396 - 1.11E+06 - - - 2.9848 - 1.485 0.412 - 73.1 1 1 0 0.0037 12 0 0 0 - - - - - 3.1233 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.16954.16954.2 0.013 18-Sep K.VFEVMLATDR.S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1179.5958 1.72 13344 16954 2 1179.597209 590.8052 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3396.4 - 251362 - - - 1.1987 - 2.096 0.379 - 357.7 1 2 0 0.0014 10 0 0 0 3.32E+07 1.93E+07 - - - 3.9055 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.16955.16955.2 0.000396 18-Aug K.VFEVMLATDR[166.11].S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1189.6041 1.72 13345 16955 2 1189.606063 595.8093 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3396.5 - 125250 - - - 1.6796 - 1.936 0.411 - 235 1 2 0 0.002 10 0 0 0 3.32E+07 1.93E+07 - - - 3.92 0.999 230117_WJC_METTL3_WT_vs_EV_F02.16958.16958.2 0.00825 14-Sep K.MFAEIMMK[136.11].L "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1007.4734 0.96 13346 16958 2 1007.476504 504.744 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 5.75 3396.9 - 1.79E+06 - - - 3.1137 - 1.671 0.351 - 234.5 1 2 0 0.0031 8 0 0 0 2.11E+07 2.19E+07 - - - 3.181 0.9962 230117_WJC_METTL3_WT_vs_EV_F02.16959.16959.2 0.138 18-Sep K.VTDAIVLLDR.E "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1113.6394 2.75 13347 16959 2 1113.642969 557.827 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.21 3397.1 - 832804 - - - 3.2282 - 1.627 0.19 - 130.2 1 2 0 0.0036 10 0 0 0 2.06E+08 7.47E+07 - - - 1.8018 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.16960.16960.2 0.014 18-Oct R.LGLSTLGELK.Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1029.607 2.59 13348 16960 2 1029.609338 515.8108 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3397.1 - 4.22E+06 - - - 2.2601 - 1.911 0.275 - 201.5 1 2 0 0.0023 10 0 0 0 3.82E+08 1.48E+08 - - - 2.8791 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.16961.16961.2 0.000404 16-Aug R.ELLTEFGYK[136.11].G sp|P49411|EFTU_HUMAN 1 1106.5739 2.99 13349 16961 2 1106.574218 554.2942 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.53 3397.2 - 548268 - - - 0.263 - 1.799 0.35 - 162.8 1 2 0 0.0003 9 0 0 0 6.33E+07 2.12E+07 - - - 3.3249 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.16962.16962.2 1.13E-06 18-Oct R.LLYEALVDC[160.03]K[136.11].K "sp|Q7L2H7|EIF3M_HUMAN,tr|J3KNJ2|J3KNJ2_HUMAN,tr|E9PRY0|E9PRY0_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 4 1230.641 1 13350 16962 2 1230.636943 616.3278 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 4.37 3397.4 - 440522 - - - -3.265 - 1.877 0.502 - 320.8 1 2 0 -0.004 10 0 0 0 7.28E+06 7.28E+06 - - - 4.5051 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.16963.16963.2 0.0332 12-Jul K.LLLDMYK.S "sp|O75150|BRE1B_HUMAN,tr|H3BP71|H3BP71_HUMAN" 2 894.4885 0.79 13351 16963 2 894.490553 448.2515 E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5 5.83 3397.5 - 382450 - - - 2.322 - 1.466 0.334 - 128.4 1 2 0 0.0021 7 0 0 0 1.05E+07 1.32E+07 - - - 2.7194 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.16969.16969.2 0.000213 18-Sep R.LGLSTLGELK[136.11].Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1037.6212 2.59 13355 16969 2 1037.622733 519.8179 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3398.3 - 421312 - - - 1.4668 - 1.995 0.436 - 156.8 1 2 0 0.0015 10 0 0 0 3.82E+08 1.48E+08 - - - 4.1886 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.16971.16971.2 0.00837 16-Jul R.ELLTEFGYK.G sp|P49411|EFTU_HUMAN 1 1098.5597 2.98 13357 16971 2 1098.560599 550.2871 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.53 3398.3 - 1.35E+06 - - - 0.7938 - 1.419 0.445 - 154.1 1 2 0 0.0009 9 0 0 0 6.32E+07 2.12E+07 - - - 3.3399 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.16972.16972.2 0.0759 12-Jul R.VPFSLLR.G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 830.5014 0.98 13358 16972 2 830.501947 416.258 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3398.4 - 506793 - - - 0.6297 - 1.437 0.247 - 209.8 1 2 0 0.0005 7 0 0 0 9.41E+07 9.55E+07 - - - 2.014 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.16977.16977.2 0.0714 16-Aug R.LVSLYFDTK[136.11].R "sp|O00231|PSD11_HUMAN,tr|J3QRY4|J3QRY4_HUMAN,tr|J3KSW3|J3KSW3_HUMAN" 3 1092.5947 1.68 13361 16977 2 1092.59603 547.3046 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 5.83 3399 - 1.59E+06 - - - 1.2521 - 1.827 0.118 - 202.9 1 2 0 0.0014 9 0 0 0 7.35E+07 4.39E+07 - - - 1.6557 0.9966 230117_WJC_METTL3_WT_vs_EV_F02.16978.16978.2 0.101 12-Jul R.VPFSLLR[166.11].G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 840.5097 0.98 13362 16978 2 840.510419 421.2621 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3399.1 - 1.15E+06 - - - 0.8626 - 1.304 0.194 - 220.3 1 2 0 0.0007 7 0 0 0 9.43E+07 9.66E+07 - - - 1.3147 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.16986.16986.2 0.013 14-Jul R.VLFLSTVR.T "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 933.5648 2.07 13368 16986 2 933.565681 467.7897 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 9.72 3400.1 - 1.61E+06 - - - 0.994 - 1.618 0.343 - 134.2 1 2 0 0.0009 8 0 0 0 6.93E+07 3.34E+07 - - - 3.0254 1 230117_WJC_METTL3_WT_vs_EV_F02.16987.16987.2 0.00138 14-Sep K.VDLVLLGK[136.11].Q sp|P38117|ETFB_HUMAN 1 863.5572 2.43 13369 16987 2 863.557605 432.7859 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3400.1 - 1.02E+06 - - - 0.5223 - 2.11 0.473 - 314.2 1 2 0 0.0005 8 0 0 0 2.15E+08 8.83E+07 - - - 4.7864 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.16996.16996.2 0.00657 22-Aug K.VLQGDLVMNVYR[166.11].D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1415.747 2.29 13378 16996 2 1415.750527 708.8808 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3401.2 - 105046 - - - 2.4623 - 1.724 0.314 - 171.8 1 2 0 0.0035 12 0 0 0 4.46E+06 1.95E+06 - - - 2.7922 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.16998.16998.2 0.00706 20-Aug K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 4.01 13379 16998 2 1235.762025 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3401.4 - 1.12E+06 - - - 1.5108 - 1.796 0.298 - 144 1 2 0 0.0019 11 0 0 0 3.68E+07 9.16E+06 - - - 2.8255 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17000.17000.2 0.00307 14-Sep K.VDLVLLGK.Q sp|P38117|ETFB_HUMAN 1 855.543 1.77 13380 17000 2 855.544999 428.7788 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3401.6 - 5.07E+06 - - - 2.3903 - 1.997 0.443 - 311.7 1 2 0 0.002 8 0 0 0 1.18E+08 6.67E+07 - - - 4.3983 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17003.17003.2 0.0452 16-Aug K.VGGLLAFAK.R "sp|P28340|DPOD1_HUMAN,tr|M0R3H8|M0R3H8_HUMAN,tr|M0QXQ2|M0QXQ2_HUMAN,tr|M0QXE6|M0QXE6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 874.5276 1.09 13383 17003 2 874.528892 438.2711 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.72 3401.8 - 2.50E+06 - - - 1.4328 - 1.725 0.343 - 161.2 1 2 0 0.0013 9 0 0 0 2.53E+07 2.32E+07 - - - 3.1514 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.17004.17004.2 0.02 14-Aug K.AGPIWDLR.L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 926.4974 0.92 13384 17004 2 926.498013 464.256 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3401.8 - 1.75E+06 - - - 0.6606 - 1.578 0.295 - 286.3 1 2 0 0.0006 8 0 0 0 4.81E+08 5.25E+08 - - - 2.5954 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17010.17010.2 2.34E-05 20-Oct R.IDGLAALSMDR.T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1160.586 1.6 13388 17010 2 1160.586736 581.3003 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3402.5 - 1.34E+06 - - - 0.6704 - 2.204 0.425 - 250 1 2 0 0.0008 11 0 0 0 3.21E+07 2.00E+07 - - - 4.3177 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.17012.17012.2 0.00351 22-Dec R.AAVLFATDIAAR[166.11].G "sp|Q13206|DDX10_HUMAN,tr|A0A3B3ISR7|A0A3B3ISR7_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 3 1227.6851 0.66 13390 17012 2 1227.689375 614.8498 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 5.88 3402.8 - 329426 - - - 3.4887 - 2.087 0.287 - 276.7 1 2 0 0.0043 12 0 0 0 4.58E+06 6.97E+06 - - - 3.0953 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17018.17018.2 0.0546 14-Sep K.AGPIWDLR[166.11].L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 936.5057 0.92 13394 17018 2 936.507197 469.2601 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3403.5 - 5.32E+06 - - - 1.6295 - 1.753 0.301 - 377.7 1 2 0 0.0015 8 0 0 0 4.81E+08 5.25E+08 - - - 2.9566 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.17019.17019.2 0.00481 14-Aug K.MFGMVLEK.L sp|P55060|XPO2_HUMAN 1 953.4714 2.17 13395 17019 2 953.473614 477.743 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.75 3403.5 - 2.16E+06 - - - 2.2738 - 1.37 0.424 - 186.5 1 2 0 0.0022 8 0 0 0 8.71E+07 4.01E+07 - - - 3.1214 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17029.17029.2 0.000334 20-Sep R.IDGLAALSMDR[166.11].T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1170.5942 1.62 13401 17029 2 1170.595602 586.3044 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3404.8 - 294662 - - - 1.1738 - 2.07 0.457 - 196.6 1 2 0 0.0014 11 0 0 0 3.22E+07 1.98E+07 - - - 4.3842 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.17033.17033.2 0.0418 14-Sep K.IMLAIITK.M "sp|P78412|IRX6_HUMAN,sp|P78414|IRX1_HUMAN,sp|P78413|IRX4_HUMAN,sp|Q9BZI1|IRX2_HUMAN,sp|P78411|IRX5_HUMAN,sp|P78415|IRX3_HUMAN,tr|D6RAS8|D6RAS8_HUMAN" 7 901.5671 0.67 13403 17033 2 901.568017 451.7908 Iroquois-class homeodomain protein IRX-6 OS=Homo sapiens OX=9606 GN=IRX6 PE=1 SV=3 8.75 3405.2 - 614940 - - - 1.0604 - 1.463 0.358 - 153.3 1 2 0 0.001 8 0 0 0 1.34E+07 2.01E+07 - - - 2.8324 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17037.17037.2 0.000112 22-Nov R.AAVLFATDIAAR.G "sp|Q13206|DDX10_HUMAN,tr|A0A3B3ISR7|A0A3B3ISR7_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 3 1217.6768 0.7 13407 17037 2 1217.680053 609.8457 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 5.88 3405.7 - 206889 - - - 2.6534 - 2.367 0.303 - 426.7 1 2 0 0.0032 12 0 0 0 4.64E+06 6.64E+06 - - - 3.545 0.9614 230117_WJC_METTL3_WT_vs_EV_F02.17040.17040.2 0.00052 14-Sep K.PFYPALIR[166.11].Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 985.5625 0.73 13408 17040 2 985.563753 493.7885 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.18 3406.1 - 7.54E+06 - - - 1.314 - 1.73 0.34 - 359.7 1 1 0 0.0013 8 0 0 0 7.00E+07 9.64E+07 - - - 3.2049 0.9953 230117_WJC_METTL3_WT_vs_EV_F02.17042.17042.2 0.0063 18-Oct R.LVLSTFSNIR.E sp|Q8WVV4|POF1B_HUMAN 1 1148.6554 999 13410 17042 2 1148.662242 575.335 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 9.75 3406.3 - 584982 - - - 5.9922 - 1.769 0.433 - 247.5 1 2 0 0.0069 10 0 0 0 1.25E+07 0.00E+00 - - - 3.8292 0.9595 230117_WJC_METTL3_WT_vs_EV_F02.17043.17043.2 5.03 16-Sep K.AILVVFANK.Q "sp|P40616|ARL1_HUMAN,tr|B4DZG7|B4DZG7_HUMAN,tr|F8VYN9|F8VYN9_HUMAN" 3 973.5961 0.34 13411 17043 2 973.59708 487.8053 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 8.8 3406.4 - 5.18E+06 - - - 1.0549 - 1.16 0.011 - 174.6 1 2 0 0.001 9 0 0 0 9.39E+07 2.78E+08 - - - -0.4487 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17048.17048.2 0.00053 12-Jul R.YGDFFIR.Q "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|H0Y7E6|H0Y7E6_HUMAN,tr|B0QY90|B0QY90_HUMAN" 4 916.4443 0.6 13414 17048 2 916.445492 459.2294 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 5.84 3407 - 2.56E+06 - - - 1.2974 - 1.574 0.484 - 141.5 1 2 0 0.0012 7 0 0 0 5.28E+07 8.75E+07 - - - 4.0528 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.17050.17050.2 0.0805 12-Aug R.DGFGFIK.C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 782.3963 1.53 13416 17050 2 782.397181 392.2054 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3407.2 - 1.91E+06 - - - 1.1388 - 1.074 0.305 - 227.4 1 2 0 0.0009 7 0 0 0 6.65E+07 4.34E+07 - - - 1.5197 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.17053.17053.2 0.194 18-Sep R.LINLVGESLR[166.11].L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1122.6636 3.75 13417 17053 2 1122.664447 562.3391 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6 3407.6 - 1.21E+06 - - - 0.7286 - 1.932 0.159 - 266.2 1 2 0 0.0008 10 0 0 0 3.09E+08 8.24E+07 - - - 2.0533 0.8921 230117_WJC_METTL3_WT_vs_EV_F02.17057.17057.2 0.806 14-Jul K.FLSLPEVR.Q "sp|Q9H3G5|CPVL_HUMAN,tr|H7C0X5|H7C0X5_HUMAN" 2 959.544 2.82 13421 17057 2 959.549365 480.7793 Probable serine carboxypeptidase CPVL OS=Homo sapiens OX=9606 GN=CPVL PE=1 SV=2 6 3407.9 - 404795 - - - 5.5735 - 1.354 0.057 - 128.4 1 2 0 0.0053 8 0 0 0 3.43E+07 1.22E+07 - - - 0.3743 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.17064.17064.2 0.0508 12-Jun R.DGFGFIK[136.11].C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 790.4105 1.95 13426 17064 2 790.412145 396.2125 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3408.7 - 1.67E+06 - - - 2.0938 - 1.319 0.278 - 145.9 1 2 0 0.0017 7 0 0 0 6.46E+07 3.31E+07 - - - 1.9711 0.9962 230117_WJC_METTL3_WT_vs_EV_F02.17066.17066.2 0.089 18-Jun R.IFLPPPPGIR.K "sp|Q8IX18|DHX40_HUMAN,tr|F5H625|F5H625_HUMAN" 2 1105.6648 1.75 13428 17066 2 1105.668006 553.8397 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 9.75 3408.9 - 213602 - - - 2.8987 - 1.331 0.244 - 68.6 1 2 0 0.0032 10 0 0 0 1.43E+07 8.15E+06 - - - 1.6403 0.98 230117_WJC_METTL3_WT_vs_EV_F02.17070.17070.2 0.0105 20-Nov K.ALADVATVLGR.A "sp|Q92542|NICA_HUMAN,tr|H0Y6T7|H0Y6T7_HUMAN" 2 1084.6241 2.33 13430 17070 2 1084.61871 543.3193 Nicastrin OS=Homo sapiens OX=9606 GN=NCSTN PE=1 SV=2 5.88 3409.4 - 578082 - - - -4.9307 - 1.959 0.278 - 308.3 1 2 0 -0.0053 11 0 0 0 1.23E+07 5.26E+06 - - - 2.9117 0.967 230117_WJC_METTL3_WT_vs_EV_F02.17071.17071.2 0.00132 16-Sep F.VLVLYDEIK.K "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 3 1090.6274 0.22 13431 17071 2 1090.627395 546.321 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 4.37 3409.4 - 488278 - - - -0.0156 - 1.953 0.437 - 260.5 1 1 0 0 9 0 0 0 2.23E+07 9.99E+07 - - - 4.2052 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17072.17072.2 0.000205 18-Aug R.FFNYVPSGIR[166.11].C "sp|Q969X6|UTP4_HUMAN,tr|H3BPD7|H3BPD7_HUMAN" 2 1208.6218 1.24 13432 17072 2 1208.623669 605.3182 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 8.75 3409.5 - 722807 - - - 1.5762 - 1.547 0.4 - 195.2 1 2 0 0.0019 10 0 0 0 1.20E+07 9.65E+06 - - - 3.2127 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.17077.17077.2 0.297 14-May R.ITVLEALR.H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 913.5597 1.21 13435 17077 2 913.561825 457.7871 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3410.2 - 2.80E+06 - - - 2.3622 - 1.403 0.294 - 90.4 1 2 0 0.0022 8 0 0 0 1.58E+08 1.30E+08 - - - 2.233 0.9924 230117_WJC_METTL3_WT_vs_EV_F02.17083.17083.2 0.187 16-Jul R.GLVGEIIK[136.11]R[166.11].F "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1001.6352 1.82 13439 17083 2 1001.635653 501.8249 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3410.8 - 7.58E+06 - - - 0.4173 - 1.387 0.11 - 129.7 1 2 0 0.0004 9 0 0 0 2.96E+08 1.62E+08 - - - 0.7998 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17091.17091.2 0.00671 14-Sep R.ITVLEALR[166.11].H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 923.5679 1.2 13445 17091 2 923.570313 462.7912 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3411.9 - 6.20E+06 - - - 2.5726 - 1.865 0.392 - 294.8 1 2 0 0.0024 8 0 0 0 1.58E+08 1.32E+08 - - - 3.8153 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.17093.17093.2 0.044 14-Oct K.AGISFIIK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 847.5167 0.89 13447 17093 2 847.51811 424.7656 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.8 3412 - 2.17E+06 - - - 1.6165 - 1.661 0.146 - 255.8 1 2 0 0.0014 8 0 0 0 2.02E+09 2.27E+09 - - - 1.6493 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.17094.17094.2 0.00556 14-Oct R.LDNIFLTR.M "sp|Q9BQ52|RNZ2_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|V9GYS7|V9GYS7_HUMAN,tr|J3QLK4|J3QLK4_HUMAN,tr|V9GYU5|V9GYU5_HUMAN,tr|V9GZ72|V9GZ72_HUMAN,tr|J3QL08|J3QL08_HUMAN,tr|J3QRS2|J3QRS2_HUMAN" 8 990.5498 0.14 13448 17094 2 990.553945 496.2822 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 5.84 3412.1 - 3.42E+06 - - - 4.1532 - 1.882 0.392 - 361.6 1 2 0 0.0041 8 0 0 0 3.89E+07 2.68E+08 - - - 3.8421 0.9939 230117_WJC_METTL3_WT_vs_EV_F02.17095.17095.2 1.06 14-Jul R.EILETLIK[136.11].G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 965.5888 1.55 13449 17095 2 965.590728 483.8017 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3412.2 - 1.06E+06 - - - 1.946 - 1.446 0.1 - 150.1 1 2 0 0.0019 8 0 0 0 1.64E+08 1.06E+08 - - - 0.8913 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.17100.17100.2 0.0728 16-Aug R.VLIFSQMTR[166.11].V "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 1103.6037 0.94 13454 17100 2 1103.605233 552.8091 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 9.72 3412.8 - 329743 - - - 1.4154 - 1.715 0.267 - 177.3 1 2 0 0.0016 9 0 0 0 2.26E+07 2.40E+07 - - - 2.5731 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.17103.17103.2 0.021 18-Oct R.LLDYVPIGPR.F "sp|P46459|NSF_HUMAN,tr|K7EQD6|K7EQD6_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 4 1141.6495 1.51 13456 17103 2 1141.653042 571.832 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.84 3413.1 - 1.88E+06 - - - 3.0631 - 2.039 0.336 - 293.4 1 2 0 0.0035 10 0 0 0 4.38E+07 2.90E+07 - - - 3.5103 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17104.17104.2 0.0125 14-Sep K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 0.96 13457 17104 2 988.572295 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3413.2 - 5.59E+06 - - - 1.749 - 1.779 0.36 - 380.2 1 2 0 0.0017 8 0 0 0 5.32E+08 5.53E+08 - - - 3.4368 0.9627 230117_WJC_METTL3_WT_vs_EV_F02.17105.17105.2 0.00954 16-Aug F.ADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 952.5957 12.43 13458 17105 2 952.597768 477.3051 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3413.3 - 2.72E+06 - - - 2.152 - 1.624 0.414 - 209.7 1 1 0 0.0021 9 0 0 0 4.09E+07 3.29E+06 - - - 3.501 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.17106.17106.2 0.0464 16-Oct R.LLDLELTSR.F "sp|Q9Y2Q9|RT28_HUMAN,tr|H0YAT2|H0YAT2_HUMAN,tr|E5RK86|E5RK86_HUMAN,tr|E5RGC7|E5RGC7_HUMAN,tr|E5RFH3|E5RFH3_HUMAN" 5 1058.5972 1.28 13459 17106 2 1058.602062 530.3059 "28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1" 4.37 3413.3 - 1.69E+06 - - - 4.6165 - 2.073 0.243 - 280 1 2 0 0.0049 9 0 0 0 3.38E+07 2.65E+07 - - - 2.9433 0.9933 230117_WJC_METTL3_WT_vs_EV_F02.17107.17107.2 1.22 14-Sep K.LILAGALR[166.11].L "sp|Q13614|MTMR2_HUMAN,tr|A0A6Q8PHS7|A0A6Q8PHS7_HUMAN,tr|C9JEX3|C9JEX3_HUMAN,tr|A0A6Q8PGS5|A0A6Q8PGS5_HUMAN,tr|A0A6Q8PHL9|A0A6Q8PHL9_HUMAN" 5 835.5519 1.26 13460 17107 2 835.553423 418.7832 Myotubularin-related protein 2 OS=Homo sapiens OX=9606 GN=MTMR2 PE=1 SV=4 9.75 3413.5 - 1.50E+06 - - - 1.8311 - 1.72 0.035 - 247.3 2 2 0 0.0015 8 0 0 0 5.77E+07 4.57E+07 - - - 0.8002 0.9949 230117_WJC_METTL3_WT_vs_EV_F02.17112.17112.2 1.35 14-Jul R.EILETLIK.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 957.5746 1.55 13464 17112 2 957.57702 479.7946 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3414.1 - 1.37E+07 - - - 2.476 - 1.357 0.167 - 175.3 1 2 0 0.0024 8 0 0 0 1.64E+08 1.06E+08 - - - 1.1944 0.9489 230117_WJC_METTL3_WT_vs_EV_F02.17114.17114.2 3.21 14-Jun K.FIIPNVVK[136.11].Y "sp|P00338|LDHA_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 3 936.5888 0.91 13466 17114 2 936.590186 469.3017 L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2 8.75 3414.2 - 3.31E+06 - - - 1.4916 - 1.047 0.047 - 96.5 2 2 0 0.0014 8 0 0 0 5.40E+07 5.96E+07 - - - -0.6082 0.9927 230117_WJC_METTL3_WT_vs_EV_F02.17118.17118.2 0.204 12-Jul K.ISFELMR.E "sp|Q9UNE7|CHIP_HUMAN,tr|H3BUD0|H3BUD0_HUMAN,tr|H3BTA3|H3BTA3_HUMAN" 3 894.4633 3.31 13470 17118 2 894.461237 448.2389 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 6 3414.5 - 649353 - - - -2.3332 - 1.435 0.278 - 127.1 1 2 0 -0.0021 7 0 0 0 3.29E+07 9.93E+06 - - - 2.238 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.17124.17124.2 0.0372 16-Sep K.SSLNPILFR.G "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1045.592 1.37 13474 17124 2 1045.594543 523.8033 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 9.47 3415.1 - 2.32E+06 - - - 2.4034 - 1.758 0.237 - 276.4 1 2 0 0.0025 9 0 0 0 1.30E+08 9.48E+07 - - - 2.4229 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17125.17125.2 0.0408 14-Sep K.LMNLWTER[166.11].F "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1071.5411 0.35 13475 17125 2 1071.543917 536.7778 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 3415.2 - 4.99E+06 - - - 2.656 - 1.83 0.375 - 389.4 1 2 0 0.0028 8 0 0 0 2.69E+08 7.78E+08 - - - 3.6324 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.17126.17126.2 0.00557 16-Jul K.SSLNPILFR[166.11].G "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1055.6003 1.37 13476 17126 2 1055.603164 528.8074 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 9.47 3415.3 - 2.35E+06 - - - 2.7131 - 1.705 0.255 - 132.4 1 2 0 0.0029 9 0 0 0 1.30E+08 9.44E+07 - - - 2.4672 0.9963 230117_WJC_METTL3_WT_vs_EV_F02.17127.17127.2 2.79 12-Jun R.EIVWLER.E "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 943.5127 1.63 13477 17127 2 943.514807 472.7636 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 4.53 3415.3 - 2.26E+06 - - - 2.2151 - 1.352 0.183 - 198.1 1 2 0 0.0021 7 0 0 0 5.61E+07 3.44E+07 - - - 1.3476 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17135.17135.2 0.00366 18-Sep R.LGGIGQFLAK[136.11].A sp|Q08211|DHX9_HUMAN 1 1010.6004 0.83 13483 17135 2 1010.602771 506.3075 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3416.3 - 779744 - - - 2.3303 - 1.799 0.351 - 178.8 1 2 0 0.0024 10 0 0 0 3.61E+08 4.38E+08 - - - 3.2719 0.999 230117_WJC_METTL3_WT_vs_EV_F02.17136.17136.2 0.00117 16-Sep K.LNNLVLFDK[136.11].A sp|P62851|RS25_HUMAN 1 1082.6215 1.05 13484 17136 2 1082.620164 542.318 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3416.3 - 551077 - - - -1.2765 - 2.243 0.364 - 226.9 1 2 0 -0.0014 9 0 0 0 1.06E+09 1.01E+09 - - - 4.0661 0.8648 230117_WJC_METTL3_WT_vs_EV_F02.17137.17137.2 3.07 12-May K.EGIILFK.E sp|P05455|LA_HUMAN 1 818.4902 1.03 13485 17137 2 818.490079 410.2524 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 6.1 3416.5 - 390302 - - - -0.1368 - 0.978 0.007 - 83.9 1 2 0 -0.0001 7 0 0 0 1.07E+08 1.04E+08 - - - -0.9778 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.17140.17140.2 2.09 14-Aug R.IAYFTLPK.T sp|Q92900|RENT1_HUMAN 1 951.543 0.66 13486 17140 2 951.546022 476.7788 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.59 3416.9 - 3.16E+06 - - - 3.2242 - 1.513 0.248 - 178.3 1 2 0 0.0031 8 0 0 0 4.58E+07 6.98E+07 - - - 2.1207 0.9939 230117_WJC_METTL3_WT_vs_EV_F02.17141.17141.2 0.0425 14-Jul K.AVPSWFVR[166.11].V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 970.5264 2.17 13487 17141 2 970.526547 486.2705 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3416.9 - 3.07E+06 - - - 0.1443 - 1.386 0.14 - 189.1 1 2 0 0.0001 8 0 0 0 1.31E+08 6.06E+07 - - - 1.0595 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.17142.17142.2 4.11 14-Sep R.LLLAALGR.R "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 825.5436 1.24 13488 17142 2 825.545671 413.7791 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 9.75 3417 - 4.15E+06 - - - 2.4808 - 1.671 0.132 - 223.8 1 2 0 0.002 8 0 0 0 5.66E+07 4.57E+07 - - - 1.5638 0.9907 230117_WJC_METTL3_WT_vs_EV_F02.17146.17146.2 0.255 22-Aug -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 1.59 13491 17146 2 1306.769881 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3417.5 - 279843 - - - 1.2252 - 1.398 0.081 - 109.5 1 2 0 0.0016 12 0 0 0 1.20E+07 7.52E+06 - - - 0.5203 0.958 230117_WJC_METTL3_WT_vs_EV_F02.17147.17147.2 0.0696 14-May R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 393.48 13492 17147 2 1000.556694 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3417.5 - 2.62E+06 - - - -2.6375 - 0.986 0.255 - 61.4 1 2 0 -0.0026 8 0 0 0 1.78E+08 4.52E+05 - - - 0.8811 0.9546 230117_WJC_METTL3_WT_vs_EV_F02.17148.17148.2 2.87 16-May R.AGFVPVYLR[166.11].Q "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1030.5839 0.67 13493 17148 2 1030.584577 516.2992 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 8.79 3417.6 - 1.74E+06 - - - 0.6356 - 1.055 0.046 - 71.9 1 2 0 0.0007 9 0 0 0 5.17E+07 7.74E+07 - - - -0.4646 0.9854 230117_WJC_METTL3_WT_vs_EV_F02.17149.17149.2 1.92 14-May R.IASFLQLK.N "sp|P42694|HELZ_HUMAN,tr|J3KT20|J3KT20_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 4 918.5539 0.63 13494 17149 2 918.555846 460.2842 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.75 3417.6 - 1.54E+06 - - - 2.1686 - 1.234 0.106 - 50.4 2 2 0 0.002 8 0 0 0 4.19E+07 6.64E+07 - - - 0.323 0.9841 230117_WJC_METTL3_WT_vs_EV_F02.17150.17150.2 8.26 12-Jul K.LPLISLR.L "sp|Q96RL7|VP13A_HUMAN,sp|Q6UXB3|LYPD2_HUMAN,sp|Q6DN12|MCTP2_HUMAN,tr|I6L8E2|I6L8E2_HUMAN" 4 810.5327 1.39 13495 17150 2 810.53288 406.2736 Vacuolar protein sorting-associated protein 13A OS=Homo sapiens OX=9606 GN=VPS13A PE=1 SV=2 9.75 3417.7 - 221336 - - - 0.1925 - 1.266 0.076 - 135 1 2 0 0.0002 7 0 0 0 1.45E+07 1.04E+07 - - - 0.3496 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.17153.17153.2 0.0103 14-Jun K.AVPSWFVR.V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 960.5181 2.31 13496 17153 2 960.51941 481.2663 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3418.1 - 4.45E+06 - - - 1.3253 - 1.32 0.355 - 102.6 1 2 0 0.0013 8 0 0 0 1.47E+08 6.36E+07 - - - 2.5 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17155.17155.2 0.00022 18-Sep R.VLISTDVWAR[166.11].G "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1168.648 0.95 13498 17155 2 1168.648468 585.3313 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.81 3418.3 - 1.86E+06 - - - 0.4193 - 1.984 0.468 - 232.9 1 2 0 0.0005 10 0 0 0 2.27E+08 2.40E+08 - - - 4.4099 0.9948 230117_WJC_METTL3_WT_vs_EV_F02.17170.17170.2 0.273 14-Jun R.VIPLPQWK.A sp|Q96ES7|SGF29_HUMAN 1 979.5855 1.67 13509 17170 2 979.587035 490.8 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 8.72 3420 - 435227 - - - 1.5792 - 1.141 0.206 - 102.4 1 2 0 0.0015 8 0 0 0 2.72E+07 1.63E+07 - - - 0.9598 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17174.17174.2 0.00641 18-Sep K.VALDLDPYVK.K sp|O95295|SNAPN_HUMAN 1 1131.6176 1.98 13513 17174 2 1131.618401 566.8161 SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN PE=1 SV=1 4.21 3420.4 - 1.08E+06 - - - 0.729 - 1.958 0.456 - 268.4 1 2 0 0.0008 10 0 0 0 3.09E+07 1.56E+07 - - - 4.2843 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.17180.17180.2 0.193 16-Dec K.RVLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1037.7073 1.2 13517 17180 2 1037.708836 519.8609 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3421.2 - 622108 - - - 1.4474 - 1.873 0.244 - 247 1 2 0 0.0015 9 0 0 0 1.96E+08 1.63E+08 - - - 2.6582 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17185.17185.2 0.00423 16-Nov K.LNNLVLFDK.A sp|P62851|RS25_HUMAN 1 1074.6073 1.05 13520 17185 2 1074.607947 538.3109 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3421.9 - 8.53E+07 - - - 0.5593 - 2.456 0.356 - 414.2 1 2 0 0.0006 9 0 0 0 1.06E+09 1.01E+09 - - - 4.2697 0.9903 230117_WJC_METTL3_WT_vs_EV_F02.17186.17186.2 1.52 12-Jun K.GLLDDLR.N sp|Q07065|CKAP4_HUMAN 1 800.4392 1.33 13521 17186 2 800.440173 401.2269 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.21 3421.9 - 1.97E+06 - - - 1.1931 - 1.201 0.118 - 138 1 2 0 0.001 7 0 0 0 3.64E+07 2.73E+07 - - - 0.4926 0.9724 230117_WJC_METTL3_WT_vs_EV_F02.17187.17187.2 1.52 14-Jul R.TFLVPEIK.S sp|Q9P1Y5|CAMP3_HUMAN 1 945.5535 0.92 13522 17187 2 945.553266 473.784 Calmodulin-regulated spectrin-associated protein 3 OS=Homo sapiens OX=9606 GN=CAMSAP3 PE=1 SV=2 5.66 3422 - 1.19E+06 - - - -0.2676 - 1.089 0.114 - 139.5 1 2 0 -0.0003 8 0 0 0 1.41E+07 1.53E+07 - - - 0.1401 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.17188.17188.2 0.0712 20-Aug K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 2.05 13523 17188 2 1245.770098 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3422.1 - 1.16E+06 - - - 1.3405 - 1.754 0.308 - 138 1 2 0 0.0017 11 0 0 0 3.59E+07 1.75E+07 - - - 2.8354 0.9799 230117_WJC_METTL3_WT_vs_EV_F02.17189.17189.2 0.0463 20-Sep R.LYPVLQQSLVR.A sp|Q5RKV6|EXOS6_HUMAN 1 1314.766 0.8 13524 17189 2 1314.774399 658.3903 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.75 3422.2 - 849944 - - - 6.4095 - 1.425 0.306 - 243.7 1 2 0 0.0084 11 0 0 0 1.08E+07 1.36E+07 - - - 2.2566 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17192.17192.2 0.000675 18-Sep K.VALDLDPYVK[136.11].K sp|O95295|SNAPN_HUMAN 1 1139.6318 1.99 13525 17192 2 1139.634084 570.8232 SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN PE=1 SV=1 4.21 3422.6 - 1.07E+06 - - - 2.0252 - 1.825 0.408 - 175.2 1 2 0 0.0023 10 0 0 0 3.08E+07 1.55E+07 - - - 3.733 0.9737 230117_WJC_METTL3_WT_vs_EV_F02.17194.17194.2 0.355 12-May K.GLLDDLR[166.11].N sp|Q07065|CKAP4_HUMAN 1 810.4475 1.33 13527 17194 2 810.448462 406.231 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.21 3422.9 - 1.56E+06 - - - 1.2018 - 1.132 0.071 - 81 2 2 0 0.001 7 0 0 0 3.65E+07 2.75E+07 - - - -0.1765 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.17204.17204.2 0.0113 14-Jun K.LFIGMISK.K "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 907.5201 1.61 13534 17204 2 907.521957 454.7673 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.75 3424.2 - 577782 - - - 2.0341 - 1.339 0.333 - 85.8 1 2 0 0.0018 8 0 0 0 1.14E+07 7.08E+06 - - - 2.3804 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.17206.17206.2 0.909 14-Jul K.GIEILLEK[136.11].L "sp|Q15397|PUM3_HUMAN,tr|S4R3K8|S4R3K8_HUMAN" 2 921.5626 0.65 13535 17206 2 921.563818 461.7886 Pumilio homolog 3 OS=Homo sapiens OX=9606 GN=PUM3 PE=1 SV=3 4.53 3424.4 - 660797 - - - 1.2848 - 1.36 0.193 - 97.1 1 2 0 0.0012 8 0 0 0 5.40E+06 8.28E+06 - - - 1.3935 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.17208.17208.2 26.4 16-Oct K.R[166.11]VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1057.7239 1.2 13536 17208 2 1057.727126 529.8692 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3424.6 - 2.24E+06 - - - 3.0745 - 1.853 0.281 - 182.9 1 2 0 0.0033 9 0 0 0 1.96E+08 1.63E+08 - - - 2.8999 0.996 230117_WJC_METTL3_WT_vs_EV_F02.17209.17209.2 0.922 12-Jun K.YLELFQR[166.11].Q "sp|Q9UBQ6|EXTL2_HUMAN,tr|C9JEG3|C9JEG3_HUMAN" 2 977.521 1 13537 17209 2 977.522685 489.7678 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 6 3424.7 - 390871 - - - 1.737 - 1.341 0.164 - 122.2 1 2 0 0.0017 7 0 0 0 9.86E+06 9.89E+06 - - - 1.1815 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17218.17218.2 1.31E-05 14-Aug K.MVGFIIGR.G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 891.5 1.41 13544 17218 2 891.499485 446.7573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3425.9 - 6.02E+06 - - - -0.627 - 1.635 0.526 - 170.6 1 2 0 -0.0006 8 0 0 0 3.93E+08 2.79E+08 - - - 4.4086 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.17221.17221.2 0.721 14-Aug K.GWGLLGPR[166.11].N "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 864.4845 0.99 13547 17221 2 864.484868 433.2495 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 9.75 3426.2 - 460764 - - - 0.3771 - 1.499 0.198 - 235.2 1 2 0 0.0003 8 0 0 0 1.66E+07 1.68E+07 - - - 1.7242 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17224.17224.2 0.00457 22-Sep R.ILYIVASDPYSR.L "sp|Q9ULT8|HECD1_HUMAN,tr|H0YJD4|H0YJD4_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN,tr|H0YJP0|H0YJP0_HUMAN" 4 1395.7398 5.65 13550 17224 2 1395.74055 698.8772 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 5.83 3426.6 - 279131 - - - 0.5252 - 1.935 0.381 - 297.9 1 2 0 0.0007 12 0 0 0 4.07E+06 7.19E+05 - - - 3.5917 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.17228.17228.2 0.011 14-Aug K.LFDFVNAK.K "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 952.5018 0.44 13552 17228 2 952.502435 477.2582 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 5.84 3427.1 - 1.76E+06 - - - 0.6478 - 1.453 0.352 - 139.8 1 2 0 0.0006 8 0 0 0 4.23E+07 9.65E+07 - - - 2.7675 0.9731 230117_WJC_METTL3_WT_vs_EV_F02.17230.17230.2 0.00545 16-Dec D.IPIILVGNK.S "sp|P55040|GEM_HUMAN,sp|Q8IXI2|MIRO1_HUMAN,tr|H7BXZ6|H7BXZ6_HUMAN" 3 965.6274 2.03 13554 17230 2 965.628938 483.821 GTP-binding protein GEM OS=Homo sapiens OX=9606 GN=GEM PE=1 SV=1 8.75 3427.3 - 714724 - - - 1.6414 - 2.219 0.339 - 372.5 1 1 0 0.0016 9 0 0 0 7.37E+06 3.62E+06 - - - 3.8503 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17231.17231.2 0.0001 22-Sep R.IVPGQFLAVDPK.G sp|Q15393|SF3B3_HUMAN 1 1282.7285 1.25 13555 17231 2 1282.731111 642.3715 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3427.4 - 670187 - - - 2.0168 - 1.982 0.474 - 183.1 1 2 0 0.0026 12 0 0 0 2.41E+07 1.93E+07 - - - 4.3412 0.9574 230117_WJC_METTL3_WT_vs_EV_F02.17235.17235.2 0.0755 22-Jul R.VINEPTAAALAY.G "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1231.6449 - 13558 17235 2 1231.646507 616.8297 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4 3427.9 - 1.96E+06 - - - 1.3429 - 1.601 0.377 - 109.8 1 1 0 0.0017 12 0 0 0 - - - - - 3.0633 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17236.17236.2 0.00504 18-Nov R.LINLVGESLR.L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1112.6554 4.54 13559 17236 2 1112.656558 557.335 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6 3428 - 1.37E+06 - - - 1.0776 - 2.357 0.27 - 363.7 1 2 0 0.0012 10 0 0 0 4.93E+07 1.09E+07 - - - 3.4281 0.9871 230117_WJC_METTL3_WT_vs_EV_F02.17238.17238.2 2.24 20-Aug K.VIVGGVDLLAK[136.11].A "sp|Q9Y496|KIF3A_HUMAN,tr|A0A087X011|A0A087X011_HUMAN,tr|H7C2F6|H7C2F6_HUMAN,tr|J3KPF9|J3KPF9_HUMAN,tr|E9PES4|E9PES4_HUMAN" 5 1090.6841 0.47 13561 17238 2 1090.684829 546.3493 Kinesin-like protein KIF3A OS=Homo sapiens OX=9606 GN=KIF3A PE=1 SV=4 5.81 3428.3 - 437620 - - - 0.6262 - 1.249 0.099 - 80.7 1 2 0 0.0007 11 0 0 0 4.99E+06 1.07E+07 - - - 0.3735 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.17240.17240.2 0.0882 24-Aug K.LLPHQLYGVVPQA.- "sp|P18887|XRCC1_HUMAN,tr|F5H8D7|F5H8D7_HUMAN" 2 1433.8031 - 13563 17240 2 1433.801653 717.9088 DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2 6.74 3428.6 - 128438 - - - -0.9987 - 1.725 0.332 - 140 1 2 0 -0.0014 13 0 0 0 - - - - - 2.892 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17245.17245.2 0.434 14-Oct R.IVEVLLMK[136.11].D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 951.5918 1.02 13566 17245 2 951.593295 476.8032 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3429.1 - 3.78E+06 - - - 1.5448 - 2.063 0.23 - 237 1 2 0 0.0015 8 0 0 0 2.91E+08 2.86E+08 - - - 2.9234 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.17247.17247.2 0.00294 22-Aug R.IVPGQFLAVDPK[136.11].G sp|Q15393|SF3B3_HUMAN 1 1290.7427 1.25 13568 17247 2 1290.746424 646.3786 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3429.3 - 718844 - - - 2.8666 - 1.76 0.298 - 141.5 1 2 0 0.0037 12 0 0 0 2.41E+07 1.93E+07 - - - 2.7283 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.17253.17253.2 0.187 14-Sep K.GWGLLGPR.N "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 854.4763 0.98 13572 17253 2 854.477376 428.2454 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 9.75 3430 - 858764 - - - 1.292 - 1.578 0.21 - 276.6 1 2 0 0.0011 8 0 0 0 1.70E+07 1.72E+07 - - - 1.9675 0.8621 230117_WJC_METTL3_WT_vs_EV_F02.17260.17260.2 0.885 14-Jul R.MYLSLIAK.S sp|Q99959|PKP2_HUMAN 1 937.5307 0.39 13579 17260 2 937.535285 469.7726 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 8.34 3431 - 131097 - - - 4.9172 - 1.177 0.049 - 105.4 1 2 0 0.0046 8 0 0 0 4.21E+06 1.09E+07 - - - -0.107 0.9969 230117_WJC_METTL3_WT_vs_EV_F02.17262.17262.2 0.00916 18-Jul K.VIPYIASQFR.K sp|Q9NU22|MDN1_HUMAN 1 1192.6604 0.23 13581 17262 2 1192.663686 597.3375 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 8.72 3431.2 - 95061.7 - - - 2.7183 - 1.4 0.237 - 101.9 1 2 0 0.0032 10 0 0 0 1.73E+06 7.52E+06 - - - 1.7297 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.17268.17268.2 0.221 14-Oct R.IVEVLLMK.D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 943.5776 1 13586 17268 2 943.58189 472.7961 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3432 - 1.18E+07 - - - 4.52 - 2.123 0.352 - 304.7 1 2 0 0.0043 8 0 0 0 2.92E+08 2.90E+08 - - - 3.91 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.17269.17269.2 0.00494 20-Jul K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.27 13587 17269 2 1235.765156 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3432.1 - 270760 - - - 4.0445 - 1.76 0.313 - 160.5 1 2 0 0.005 11 0 0 0 1.98E+07 1.55E+07 - - - 2.8806 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17270.17270.2 0.000803 18-Oct K.VVDLLAPYAK.G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1087.6277 1.65 13588 17270 2 1087.630081 544.8211 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3432.1 - 3.32E+06 - - - 2.146 - 2.068 0.46 - 382 1 2 0 0.0023 10 0 0 0 5.22E+08 3.17E+08 - - - 4.4659 1 230117_WJC_METTL3_WT_vs_EV_F02.17271.17271.2 0.00182 18-Dec K.VVDLLAPYAK[136.11].G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1095.6419 1.65 13589 17271 2 1095.644523 548.8282 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3432.2 - 2.51E+06 - - - 2.3511 - 2.196 0.502 - 506.9 1 2 0 0.0026 10 0 0 0 5.23E+08 3.17E+08 - - - 4.9437 0.9857 230117_WJC_METTL3_WT_vs_EV_F02.17272.17272.2 0.682 12-Jun R.GFLYFNR.Q sp|Q10570|CPSF1_HUMAN 1 915.4603 1.58 13590 17272 2 915.460915 458.7374 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3432.2 - 1.06E+06 - - - 0.686 - 1.039 0.153 - 133.7 1 2 0 0.0006 7 0 0 0 8.30E+06 5.26E+06 - - - 0.2921 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.17275.17275.2 0.0397 14-Jul R.GIVTFQFR[166.11].G sp|P26572|MGAT1_HUMAN 1 976.537 0.41 13593 17275 2 976.539177 489.2758 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 9.75 3432.5 - 518391 - - - 2.259 - 1.631 0.264 - 195 1 2 0 0.0022 8 0 0 0 4.88E+06 1.18E+07 - - - 2.4656 1 230117_WJC_METTL3_WT_vs_EV_F02.17280.17280.2 0.000137 13/24 K.LLLGAGAVAYGVR[166.11].E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1268.748 1.41 13598 17280 2 1268.751155 635.3813 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3433.1 - 213618 - - - 2.4654 - 2.496 0.437 - 558.7 1 2 0 0.0031 13 0 0 0 2.34E+08 1.65E+08 - - - 4.6153 1 230117_WJC_METTL3_WT_vs_EV_F02.17285.17285.2 0.000106 24-Dec K.LLLGAGAVAYGVR.E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1258.7398 1.41 13601 17285 2 1258.742253 630.3772 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3433.6 - 492409 - - - 1.9829 - 2.296 0.47 - 437.1 1 2 0 0.0025 13 0 0 0 2.34E+08 1.65E+08 - - - 4.6449 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.17306.17306.2 1.06 16-May R.AFLGQVLVR.R "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1001.6022 0.32 13618 17306 2 1001.603916 501.8084 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 9.79 3436.2 - 5.44E+06 - - - 1.7123 - 1.337 0.261 - 78.9 2 2 0 0.0017 9 0 0 0 1.02E+08 3.20E+08 - - - 1.674 0.8947 230117_WJC_METTL3_WT_vs_EV_F02.17307.17307.2 0.101 12-May R.DFYFSVK.L sp|Q9NY12|GAR1_HUMAN 1 904.4331 0.68 13619 17307 2 904.438408 453.2238 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3436.3 - 2.35E+06 - - - 5.902 - 0.993 0.207 - 95.5 1 2 0 0.0053 7 0 0 0 7.50E+07 1.10E+08 - - - 0.546 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17308.17308.2 0.00447 20-Oct R.LYPVLQQSLVR[166.11].A sp|Q5RKV6|EXOS6_HUMAN 1 1324.7742 1.04 13620 17308 2 1324.776956 663.3944 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.75 3436.4 - 1.93E+06 - - - 2.0487 - 1.781 0.438 - 365 1 2 0 0.0027 11 0 0 0 4.81E+07 4.61E+07 - - - 3.8366 0.9868 230117_WJC_METTL3_WT_vs_EV_F02.17309.17309.2 0.596 14-Jul R.LLNIWQER.S sp|Q9NQG5|RPR1B_HUMAN 1 1070.5873 3.25 13621 17309 2 1070.592307 536.3009 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 6 3436.5 - 1.78E+06 - - - 4.6965 - 1.805 0.103 - 148.1 1 2 0 0.005 8 0 0 0 9.72E+07 2.99E+07 - - - 1.5813 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.17310.17310.2 0.13 16-Oct R.TPLDLAAFK[136.11].G "sp|O15084|ANR28_HUMAN,tr|B4DIW9|B4DIW9_HUMAN" 2 982.5579 1.71 13622 17310 2 982.56055 492.2862 Serine\threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5 5.5 3436.6 - 1.32E+06 - - - 2.7143 - 1.751 0.373 - 305.3 1 2 0 0.0027 9 0 0 0 1.78E+07 1.04E+07 - - - 3.4158 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.17312.17312.2 0.692 12-Jun R.VLFSLVK.R "sp|Q14999|CUL7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 2 804.5109 1.01 13624 17312 2 804.512921 403.2627 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 8.72 3436.8 - 845158 - - - 2.4798 - 1.502 0.164 - 112.2 2 2 0 0.002 7 0 0 0 6.31E+06 6.24E+06 - - - 1.4062 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.17313.17313.2 0.0562 12-Jul R.WLLDNVR[166.11].K "sp|Q14409|GLPK3_HUMAN,sp|P32189|GLPK_HUMAN,tr|H7C2A0|H7C2A0_HUMAN" 3 924.5057 0.94 13625 17313 2 924.507496 463.2601 Glycerol kinase 3 OS=Homo sapiens OX=9606 GN=GK3P PE=2 SV=2 5.84 3437 - 576889 - - - 1.974 - 1.402 0.297 - 155.7 1 2 0 0.0018 7 0 0 0 1.23E+07 1.31E+07 - - - 2.3047 1 230117_WJC_METTL3_WT_vs_EV_F02.17316.17316.2 8.75E-06 18-Nov K.WVGVILDEAK.G "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1128.6179 2.23 13628 17316 2 1128.623645 565.3162 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3437.4 - 436805 - - - 5.0814 - 2.279 0.503 - 322.8 1 2 0 0.0057 10 0 0 0 3.76E+07 1.69E+07 - - - 5.0537 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17320.17320.2 0.000577 14-Aug K.MVGFIIGR[166.11].G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 901.5083 1.41 13631 17320 2 901.509939 451.7614 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3437.8 - 1.05E+06 - - - 1.8025 - 1.715 0.467 - 219 1 2 0 0.0016 8 0 0 0 3.94E+08 2.80E+08 - - - 4.1166 0.9673 230117_WJC_METTL3_WT_vs_EV_F02.17322.17322.2 1.18 16-Apr R.VDQNEAEVK.K sp|Q68D86|C102B_HUMAN 1 1030.4931 21.87 13632 17322 2 1030.493432 516.2538 Coiled-coil domain-containing protein 102B OS=Homo sapiens OX=9606 GN=CCDC102B PE=1 SV=4 4.14 3438.1 - 1.43E+06 - - - 0.3183 - 1.096 0.131 - 45.8 10 2 0 0.0003 9 0 0 0 2.66E+07 1.21E+06 - - - -0.173 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17324.17324.3 2.67E-05 14/48 K.LLLGAGAVAYGVR.E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1258.7398 1.36 13634 17324 3 1258.74449 420.5872 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3438.3 - 1.35E+06 - - - 3.7601 - 2.231 0.43 - 229.5 1 2 0 0.0047 13 0 0 0 1.99E+07 1.46E+07 - - - 5.5084 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.17325.17325.2 0.0359 14-Aug R.LLNIWQER[166.11].S sp|Q9NQG5|RPR1B_HUMAN 1 1080.5955 3.25 13635 17325 2 1080.599707 541.3051 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 6 3438.5 - 1.11E+06 - - - 3.8479 - 1.928 0.197 - 221 1 2 0 0.0042 8 0 0 0 9.72E+07 2.99E+07 - - - 2.4747 1 230117_WJC_METTL3_WT_vs_EV_F02.17326.17326.2 1.72E-07 18-Dec K.VVDDEIYYFR.K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1317.6241 2.16 13636 17326 2 1317.624071 659.8193 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3438.6 - 736646 - - - -0.0357 - 2.047 0.55 - 475.2 1 2 0 0 10 0 0 0 2.64E+07 1.22E+07 - - - 5.1029 0.9723 230117_WJC_METTL3_WT_vs_EV_F02.17327.17327.2 0.594 14-Jun K.AITAATLK.F sp|P11277|SPTB1_HUMAN 1 787.4804 0.92 13637 17327 2 787.483921 394.7475 "Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB PE=1 SV=5" 8.8 3438.7 - 421807 - - - 4.5296 - 1.268 0.154 - 111.5 1 2 0 0.0036 8 0 0 0 9.64E+06 1.05E+07 - - - 0.8934 1 230117_WJC_METTL3_WT_vs_EV_F02.17329.17329.2 1.57E-07 16-Sep R.TFTNVYWMK.V sp|Q9HBH1|DEFM_HUMAN 1 1188.5638 1.17 13639 17329 2 1188.566967 595.2892 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 8.26 3439 - 330510 - - - 2.6932 - 2.054 0.546 - 254.4 1 2 0 0.0032 9 0 0 0 7.09E+06 6.05E+06 - - - 5.1551 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17330.17330.2 0.00152 13/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 3.25 13640 17330 2 1484.911127 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3439.1 - 268639 - - - 2.1833 - 2.255 0.454 - 389.9 1 2 0 0.0032 15 0 0 0 2.04E+07 6.28E+06 - - - 4.3924 0.9522 230117_WJC_METTL3_WT_vs_EV_F02.17331.17331.2 0.226 12-Apr R.VLFSLVK[136.11].R "sp|Q14999|CUL7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 2 812.5251 1.12 13641 17331 2 812.527793 407.2698 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 8.72 3439.2 - 250600 - - - 3.2824 - 1.17 0.107 - 43.2 8 2 0 0.0027 7 0 0 0 6.21E+06 5.56E+06 - - - -0.0755 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.17337.17337.2 1.07E-05 22-Oct R.YVVGVLEAAGVR[166.11].Y sp|Q9H9S5|FKRP_HUMAN 1 1241.7007 0.42 13645 17337 2 1241.703205 621.8576 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 6 3439.9 - 2.09E+06 - - - 1.9836 - 1.929 0.206 - 253.1 1 2 0 0.0025 12 0 0 0 1.30E+07 3.08E+07 - - - 2.2904 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.17341.17341.2 0.0295 18-Oct K.VALAVSLNLR.T "sp|Q03426|KIME_HUMAN,tr|F5GXC0|F5GXC0_HUMAN,tr|F5H163|F5H163_HUMAN,tr|F5H092|F5H092_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|F5H368|F5H368_HUMAN,tr|A0A1W2PS16|A0A1W2PS16_HUMAN" 7 1054.6499 0.94 13649 17341 2 1054.652399 528.3322 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 9.72 3440.1 - 1.19E+06 - - - 2.3894 - 2.274 0.254 - 297.5 1 2 0 0.0025 10 0 0 0 1.28E+07 1.37E+07 - - - 3.2094 0.9756 230117_WJC_METTL3_WT_vs_EV_F02.17343.17343.2 1.12 14-May K.LFAELEIK.R "sp|O75937|DNJC8_HUMAN,tr|S4R3J5|S4R3J5_HUMAN" 2 961.5484 1.09 13651 17343 2 961.548902 481.7815 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.53 3440.3 - 626807 - - - 0.4867 - 1.233 0.07 - 47.4 3 2 0 0.0005 8 0 0 0 9.97E+06 9.12E+06 - - - -0.0236 0.9626 230117_WJC_METTL3_WT_vs_EV_F02.17344.17344.2 0.192 20-Aug K.ALVMYSNLDLK[136.11].T sp|O95900|TRUB2_HUMAN 1 1273.6832 1.04 13652 17344 2 1273.691132 637.8489 Mitochondrial mRNA pseudouridine synthase TRUB2 OS=Homo sapiens OX=9606 GN=TRUB2 PE=1 SV=1 5.88 3440.4 - 553108 - - - 6.259 - 1.513 0.192 - 225.8 1 2 0 0.008 11 0 0 0 3.47E+06 3.34E+06 - - - 1.5768 1 230117_WJC_METTL3_WT_vs_EV_F02.17350.17350.2 9.70E-07 22-Oct R.YVVGVLEAAGVR.Y sp|Q9H9S5|FKRP_HUMAN 1 1231.6925 0.42 13656 17350 2 1231.694494 616.8535 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 6 3441.1 - 900286 - - - 1.6416 - 2.074 0.53 - 219.5 1 2 0 0.002 12 0 0 0 1.30E+07 3.08E+07 - - - 4.8743 1 230117_WJC_METTL3_WT_vs_EV_F02.17353.17353.2 0.00019 28-Dec R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 5.82 13659 17353 2 1494.920016 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3441.4 - 344275 - - - 2.5828 - 2.208 0.51 - 379.9 1 2 0 0.0039 15 0 0 0 6.01E+07 1.03E+07 - - - 4.754 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17357.17357.2 0.00152 16-Oct R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 0.97 13661 17357 2 997.606817 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3442 - 5.30E+06 - - - 1.654 - 2.209 0.44 - 289.8 1 2 0 0.0016 9 0 0 0 3.30E+09 3.40E+09 - - - 4.5832 1 230117_WJC_METTL3_WT_vs_EV_F02.17360.17360.2 1.46E-05 18-Nov K.VVDDEIYYFR[166.11].K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1327.6324 2.16 13664 17360 2 1327.635248 664.8235 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3442.3 - 672464 - - - 2.1542 - 1.911 0.515 - 374.8 1 2 0 0.0029 10 0 0 0 2.64E+07 1.23E+07 - - - 4.6516 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.17362.17362.2 0.698 12-Jul K.TSFFLVR[166.11].E sp|Q8TDD1|DDX54_HUMAN 1 878.489 0.81 13666 17362 2 878.490722 440.2518 ATP-dependent RNA helicase DDX54 OS=Homo sapiens OX=9606 GN=DDX54 PE=1 SV=2 9.41 3442.5 - 331502 - - - 2.0069 - 1.517 0.328 - 208.6 1 2 0 0.0018 7 0 0 0 8.37E+06 1.03E+07 - - - 2.7835 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17364.17364.2 0.106 14-Oct K.IDLTLLNR[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 966.5738 1.16 13667 17364 2 966.574702 484.2942 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.84 3442.7 - 1.84E+07 - - - 0.9839 - 2.282 0.318 - 354.1 1 2 0 0.001 8 0 0 0 1.38E+08 1.19E+08 - - - 3.8778 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17370.17370.2 0.000208 18-Oct K.WVGVILDEAK[136.11].G "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1136.6321 2.23 13672 17370 2 1136.634131 569.3233 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3443.3 - 805974 - - - 1.7781 - 2.014 0.429 - 253.5 1 2 0 0.002 10 0 0 0 3.76E+07 1.69E+07 - - - 4.1632 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17371.17371.2 0.000368 18-Oct R.VVLPIEAPIR[166.11].M sp|P00403|COX2_HUMAN 1 1115.6942 1.6 13673 17371 2 1115.694698 558.8544 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 5.97 3443.4 - 656766 - - - 0.4464 - 1.871 0.435 - 423.6 1 2 0 0.0005 10 0 0 0 5.74E+08 3.59E+08 - - - 4.0024 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17376.17376.2 0.000507 16-Nov R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.97 13677 17376 2 989.592124 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3444 - 4.61E+07 - - - 1.1692 - 2.261 0.352 - 335.4 1 2 0 0.0012 9 0 0 0 3.31E+09 3.41E+09 - - - 4.0007 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.17378.17378.2 0.0294 16-Aug K.VVLPC[160.03]NLLR[166.11].M "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1092.6353 1.72 13678 17378 2 1092.636535 547.3249 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 8.22 3444.3 - 5.32E+06 - - - 1.1248 - 1.341 0.354 - 266.1 1 2 0 0.0012 9 0 0 0 1.24E+08 7.23E+07 - - - 2.5041 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17379.17379.2 0.000962 18-Aug R.VVLPIEAPIR.M sp|P00403|COX2_HUMAN 1 1105.6859 1.6 13679 17379 2 1105.688222 553.8502 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 5.97 3444.3 - 6.77E+06 - - - 2.0729 - 1.704 0.415 - 239.2 1 2 0 0.0023 10 0 0 0 5.74E+08 3.59E+08 - - - 3.5932 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.17387.17387.2 0.0092 26-Sep K.LGGSAVISLEGKPL.- "sp|P23528|COF1_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PK25|E9PK25_HUMAN" 3 1339.7711 10.8 13687 17387 2 1339.772525 670.8928 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6 3445.2 - 395886 - - - 1.0509 - 1.647 0.244 - 125.1 1 2 0 0.0014 14 0 0 0 4.34E+06 4.02E+05 - - - 2.0948 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17389.17389.2 0.00915 18-Nov R.FSNLLGTVYR[166.11].R "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN,tr|C9J544|C9J544_HUMAN" 3 1178.6323 1.06 13689 17389 2 1178.633511 590.3234 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 8.75 3445.4 - 240711 - - - 1.0037 - 1.741 0.37 - 351.3 1 2 0 0.0012 10 0 0 0 1.02E+07 9.59E+06 - - - 3.3211 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17392.17392.2 0.00936 16-Sep R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 9946.69 13691 17392 2 1006.570424 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3445.8 - 2.86E+07 - - - 0.5226 - 1.875 0.447 - 190.1 1 2 0 0.0005 9 0 0 0 2.31E+11 2.32E+07 - - - 4.161 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17398.17398.2 0.316 18-Sep K.IYVISLAEPR.L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1159.6601 1.26 13696 17398 2 1159.662974 580.8373 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3446.5 - 418980 - - - 2.4697 - 2.087 0.376 - 333.9 1 2 0 0.0029 10 0 0 0 1.83E+08 1.44E+08 - - - 3.8709 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17400.17400.2 0.00474 18-Oct R.LLFNDVQTLK[136.11].D "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1197.6849 1.13 13698 17400 2 1197.68828 599.8497 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.84 3446.8 - 383633 - - - 2.8438 - 1.934 0.38 - 229.5 1 2 0 0.0034 10 0 0 0 3.05E+07 2.70E+07 - - - 3.6877 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.17402.17402.2 0.0361 14-Jul R.AYILNLVK.Q sp|P50991|TCPD_HUMAN 1 932.5695 7.37 13699 17402 2 932.570479 467.292 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.63 3447 - 2.39E+07 - - - 1.0455 - 1.47 0.327 - 182.5 1 2 0 0.001 8 0 0 0 1.97E+09 2.67E+08 - - - 2.6178 0.9102 230117_WJC_METTL3_WT_vs_EV_F02.17403.17403.2 6.1 16-Jul K.DDIILFSGK[136.11].V sp|O75635|SPB7_HUMAN 1 1014.5477 0.001 13700 17403 2 1014.545447 508.2811 Serpin B7 OS=Homo sapiens OX=9606 GN=SERPINB7 PE=1 SV=1 4.21 3447 - 689324 - - - -2.2325 - 1.274 0.054 - 85 1 2 0 -0.0023 9 0 0 0 0.00E+00 1.03E+07 - - - 0.1397 0.9154 230117_WJC_METTL3_WT_vs_EV_F02.17404.17404.2 0.0233 18-Oct N.PEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1087.5662 999 13701 17404 2 1087.56426 544.7904 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.43 3447.1 - 882550 - - - -1.7921 - 2.225 0.439 - 390.7 1 1 0 -0.0019 10 0 0 0 1.24E+08 0.00E+00 - - - 4.5152 0.9773 230117_WJC_METTL3_WT_vs_EV_F02.17407.17407.2 5.01 12-May K.LLLDMYR.S "sp|Q5VTR2|BRE1A_HUMAN,sp|O60308|CE104_HUMAN,tr|A0A6Q8PH38|A0A6Q8PH38_HUMAN,tr|A0A6Q8PHR0|A0A6Q8PHR0_HUMAN,tr|A0A6Q8PGF0|A0A6Q8PGF0_HUMAN,tr|J3QLL3|J3QLL3_HUMAN,tr|A0A6Q8PH69|A0A6Q8PH69_HUMAN,tr|A0A6Q8PHE1|A0A6Q8PHE1_HUMAN,tr|Q5SR27|Q5SR27_HUMAN,tr|A0A6Q8PGB3|A0A6Q8PGB3_HUMAN,tr|A0A6Q8PFR4|A0A6Q8PFR4_HUMAN" 11 922.4946 11.26 13704 17407 2 922.496525 462.2546 E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2 5.84 3447.4 - 566072 - - - 2.0607 - 1.023 0.12 - 51.8 1 2 0 0.0019 7 0 0 0 3.94E+06 3.50E+05 - - - -0.0012 0.9673 230117_WJC_METTL3_WT_vs_EV_F02.17417.17417.2 0.0019 14-Sep K.FDTPFLPK.P sp|Q14684|RRP1B_HUMAN 1 963.5066 1.39 13712 17417 2 963.508369 482.7606 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.84 3448.6 - 657441 - - - 1.8682 - 1.685 0.401 - 183.1 1 1 0 0.0018 8 0 0 0 1.37E+08 9.88E+07 - - - 3.5758 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17418.17418.2 0.0024 20-Oct R.FLPEFAGTQLK.L sp|Q9UBZ4|APEX2_HUMAN 1 1249.6707 1.86 13713 17418 2 1249.672799 625.8426 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 6 3448.8 - 627287 - - - 1.7004 - 1.739 0.329 - 318.7 1 2 0 0.0021 11 0 0 0 1.03E+08 5.53E+07 - - - 2.9672 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.17422.17422.2 0.0684 18-Jun K.IYVISLAEPR[166.11].L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1169.6684 1.26 13716 17422 2 1169.668793 585.8415 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3449.2 - 1.44E+06 - - - 0.3531 - 1.708 0.25 - 116.1 3 2 0 0.0004 10 0 0 0 1.83E+08 1.44E+08 - - - 2.1685 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.17424.17424.2 0.0164 12-Jul K.FIDPFC[160.03]R.L sp|P56182|RRP1_HUMAN 1 953.4429 1.07 13718 17424 2 953.441259 477.7287 Ribosomal RNA processing protein 1 homolog A OS=Homo sapiens OX=9606 GN=RRP1 PE=1 SV=1 5.83 3449.5 - 786029 - - - -1.7453 - 1.337 0.419 - 135.8 1 2 0 -0.0017 7 0 0 0 1.58E+07 1.47E+07 - - - 3.0554 1 230117_WJC_METTL3_WT_vs_EV_F02.17449.17449.2 5.14E-05 18-Nov R.AAGVVLEMIR[166.11].E "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN,tr|M0QXI6|M0QXI6_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 4 1067.6037 1.5 13734 17449 2 1067.607437 534.8091 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6.05 3452.6 - 1.39E+06 - - - 3.5275 - 2.305 0.477 - 583.3 1 2 0 0.0038 10 0 0 0 4.98E+07 3.32E+07 - - - 4.8939 1 230117_WJC_METTL3_WT_vs_EV_F02.17463.17463.2 0.000284 16-Nov R.PLVALLDGR.D "sp|P56545|CTBP2_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|E7ESU7|E7ESU7_HUMAN,tr|E7EUB3|E7EUB3_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|E7EPF8|E7EPF8_HUMAN,tr|E9PGB1|E9PGB1_HUMAN" 7 952.5706 1.57 13740 17463 2 952.568502 477.2926 C-terminal-binding protein 2 OS=Homo sapiens OX=9606 GN=CTBP2 PE=1 SV=1 6.27 3454.3 - 2.60E+06 - - - -2.1668 - 2.351 0.423 - 516.5 1 1 0 -0.0021 9 0 0 0 9.71E+07 6.19E+07 - - - 4.6377 1 230117_WJC_METTL3_WT_vs_EV_F02.17468.17468.2 3.18E-06 20-Dec R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 999 13742 17468 2 1201.602604 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3454.9 - 1.66E+06 - - - -5.4369 - 2.603 0.582 - 688 1 2 0 -0.0065 11 0 0 0 1.48E+07 0.00E+00 - - - 5.9256 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17482.17482.2 0.0156 16-Oct K.IAFAITAIK.G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 946.5852 1.19 13748 17482 2 946.587443 474.2999 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3456.6 - 0 - - - 2.4182 - 2.127 0.3 - 265.5 1 2 0 0.0023 9 0 0 0 5.16E+09 4.34E+09 - - - 3.4395 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.17486.17486.2 0.0867 16-Oct K.IAFAITAIK[136.11].G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 954.5994 1.19 13749 17486 2 954.602663 478.307 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3457.1 - 2.28E+06 - - - 3.4664 - 2.155 0.261 - 229.5 1 2 0 0.0033 9 0 0 0 5.16E+09 4.34E+09 - - - 3.189 0.999 230117_WJC_METTL3_WT_vs_EV_F02.17488.17488.2 0.0695 14-Sep R.GIFEPFGK.L "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 893.4647 0.86 13750 17488 2 893.466136 447.7396 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 6 3457.3 - 2.32E+06 - - - 1.6027 - 1.362 0.333 - 234.6 1 2 0 0.0014 8 0 0 0 1.21E+08 1.39E+08 - - - 2.4319 0.955 230117_WJC_METTL3_WT_vs_EV_F02.17490.17490.2 0.0343 14-Nov Y.LDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 843.5066 905.98 13751 17490 2 843.50679 422.7606 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.84 3457.5 - 1.79E+06 - - - 0.262 - 2.036 0.293 - 358 1 1 0 0.0002 8 0 0 0 1.06E+08 1.18E+05 - - - 3.3493 0.9962 230117_WJC_METTL3_WT_vs_EV_F02.17491.17491.2 0.000706 14/20 R.MGPGIGAILER[166.11].S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1122.6095 2.44 13752 17491 2 1122.605679 562.312 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.75 3457.6 - 1.48E+06 - - - -3.3894 - 2.073 0.411 - 533.1 1 2 0 -0.0038 11 0 0 0 2.24E+08 9.19E+07 - - - 4.0476 0.993 230117_WJC_METTL3_WT_vs_EV_F02.17504.17504.2 0.439 18-Jul R.LGLPGEVFGR.S sp|O95409|ZIC2_HUMAN 1 1043.5764 2.55 13760 17504 2 1043.576254 522.7955 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 6 3459.3 - 1.83E+06 - - - -0.1207 - 1.253 0.189 - 92.1 1 2 0 -0.0001 10 0 0 0 2.95E+08 1.15E+08 - - - 1.0665 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.17513.17513.2 0.396 12-Jul K.IVVLFYK.A "sp|Q9Y6E2|BZW2_HUMAN,sp|Q7L1Q6|BZW1_HUMAN,tr|B5MCH7|B5MCH7_HUMAN,tr|E9PFD4|E9PFD4_HUMAN,tr|E7ETZ4|E7ETZ4_HUMAN,tr|B5MCE7|B5MCE7_HUMAN" 6 880.5422 1.47 13762 17513 2 880.542767 441.2784 Basic leucine zipper and W2 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=BZW2 PE=1 SV=1 8.59 3460.6 - 0 - - - 0.6144 - 1.506 0.164 - 146.8 1 2 0 0.0005 7 0 0 0 2.62E+07 1.78E+07 - - - 1.5495 1 230117_WJC_METTL3_WT_vs_EV_F02.17516.17516.2 8.10E-08 14/20 R.MGPGIGAILER.S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1112.6012 2.45 13764 17516 2 1112.596519 557.3079 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.75 3460.9 - 5.75E+06 - - - -4.2198 - 2.409 0.603 - 701.8 1 2 0 -0.0047 11 0 0 0 2.26E+08 9.21E+07 - - - 5.8718 0.9781 230117_WJC_METTL3_WT_vs_EV_F02.17523.17523.2 0.0022 20-Nov R.ALTALGLAVPR.G sp|Q9BVQ7|SPA5L_HUMAN 1 1080.6655 5.78 13769 17523 2 1080.659239 541.34 Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2 9.79 3461.7 - 3.05E+06 - - - -5.8205 - 2.338 0.303 - 484.1 1 2 0 -0.0063 11 0 0 0 3.97E+07 6.87E+06 - - - 3.5745 0.9797 230117_WJC_METTL3_WT_vs_EV_F02.17524.17524.2 0.0491 16-Sep K.SALLALGLK.C sp|Q12874|SF3A3_HUMAN 1 884.5695 3.36 13770 17524 2 884.565281 443.292 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3461.8 - 1.08E+06 - - - -4.7741 - 1.847 0.265 - 232.1 1 2 0 -0.0042 9 0 0 0 2.82E+08 8.40E+07 - - - 2.772 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.17533.17533.2 0.0217 12-Aug K.ELEFYLR.K "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 968.4967 0.88 13775 17533 2 968.498088 485.2556 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.53 3462.7 - 3.41E+06 - - - 1.3991 - 1.508 0.165 - 425.6 1 2 0 0.0014 7 0 0 0 3.30E+08 3.76E+08 - - - 1.5609 0.9935 230117_WJC_METTL3_WT_vs_EV_F02.17538.17538.2 0.449 16-Jul K.LAFNSLLEK.A "sp|O75400|PR40A_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 2 1033.5808 1.9 13776 17538 2 1033.582405 517.7977 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 6 3463.4 - 6.93E+06 - - - 1.5558 - 1.403 0.146 - 110.1 5 2 0 0.0016 9 0 0 0 1.21E+08 6.39E+07 - - - 0.7862 0.9859 230117_WJC_METTL3_WT_vs_EV_F02.17541.17541.2 1.37 14-Aug K.GLGILSLK[136.11].Q sp|Q92616|GCN1_HUMAN 1 807.5309 0.8 13779 17541 2 807.528692 404.7727 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.75 3463.7 - 2.17E+06 - - - -2.7838 - 1.838 0.134 - 200.1 1 2 0 -0.0022 8 0 0 0 3.77E+07 4.74E+07 - - - 1.8658 0.9834 230117_WJC_METTL3_WT_vs_EV_F02.17542.17542.2 0.094 16-Sep K.YPQLLPGIR[166.11].G sp|P23526|SAHH_HUMAN 1 1065.621 1.09 13780 17542 2 1065.61669 533.8178 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 8.75 3463.8 - 1.05E+06 - - - -4.0774 - 1.571 0.293 - 251.2 1 2 0 -0.0043 9 0 0 0 4.82E+07 4.40E+07 - - - 2.5106 0.9905 230117_WJC_METTL3_WT_vs_EV_F02.17543.17543.2 0.0839 16-Sep K.IFTQLEEFR[166.11].A sp|O60306|AQR_HUMAN 1 1191.6163 0.83 13781 17543 2 1191.610562 596.8154 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 4.53 3464 - 0 - - - -4.8522 - 1.973 0.408 - 310.2 1 2 0 -0.0058 9 0 0 0 2.36E+07 2.84E+07 - - - 4.0187 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17548.17548.2 0.0019 18-Oct R.LGLPGEVFGR[166.11].S sp|O95409|ZIC2_HUMAN 1 1053.5847 2.55 13783 17548 2 1053.585093 527.7996 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 6 3464.6 - 704132 - - - 0.4205 - 1.885 0.42 - 258.9 1 2 0 0.0004 10 0 0 0 2.94E+08 1.15E+08 - - - 3.9125 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.17553.17553.2 4.51E-05 16-Oct K.IFTQLEEFR.A sp|O60306|AQR_HUMAN 1 1181.6081 0.84 13786 17553 2 1181.606181 591.8113 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 4.53 3465.2 - 833402 - - - -1.6021 - 2.039 0.418 - 388.1 1 2 0 -0.0019 9 0 0 0 2.36E+07 2.80E+07 - - - 4.1889 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17554.17554.2 0.0674 18-Oct R.LAGLSAALLR.T "sp|P51649|SSDH_HUMAN,tr|A0A5F9ZH98|A0A5F9ZH98_HUMAN,tr|C9J8Q5|C9J8Q5_HUMAN" 3 983.6128 1.07 13787 17554 2 983.615218 492.8137 "Succinate-semialdehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH5A1 PE=1 SV=2" 9.75 3465.3 - 519429 - - - 2.4939 - 2.064 0.317 - 265.7 1 2 0 0.0025 10 0 0 0 2.77E+07 2.59E+07 - - - 3.4043 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17560.17560.2 0.0428 16-Sep K.SALLALGLK[136.11].C sp|Q12874|SF3A3_HUMAN 1 892.5837 3.38 13790 17560 2 892.584501 447.2991 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3466.1 - 3.42E+06 - - - 0.8929 - 1.993 0.284 - 264.5 1 2 0 0.0008 9 0 0 0 2.82E+08 8.33E+07 - - - 3.1335 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17565.17565.2 0.000952 20-Aug K.LGNPIVPLNIR.L sp|P78527|PRKDC_HUMAN 1 1204.7292 0.85 13795 17565 2 1204.731055 603.3719 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3466.8 - 756131 - - - 1.5464 - 1.757 0.42 - 207.3 1 2 0 0.0019 11 0 0 0 1.47E+07 1.72E+07 - - - 3.6672 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.17567.17567.2 0.795 20-Sep R.ALTALGLAVPR[166.11].G sp|Q9BVQ7|SPA5L_HUMAN 1 1090.6738 5.78 13797 17567 2 1090.675258 546.3442 Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2 9.79 3467.1 - 619366 - - - 1.3377 - 1.725 0.179 - 175.2 1 2 0 0.0015 11 0 0 0 3.97E+07 6.87E+06 - - - 1.8376 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.17575.17575.2 0.000232 20-Aug K.LGNPIVPLNIR[166.11].L sp|P78527|PRKDC_HUMAN 1 1214.7375 0.85 13803 17575 2 1214.734626 608.376 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3467.9 - 324997 - - - -2.3347 - 1.688 0.439 - 175.8 1 2 0 -0.0028 11 0 0 0 1.47E+07 1.72E+07 - - - 3.6989 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.17578.17578.2 0.00987 14-Sep K.IIDFGLAR.R "sp|Q86YV6|MYLK4_HUMAN,sp|Q32MK0|MYLK3_HUMAN,sp|Q9H1R3|MYLK2_HUMAN,sp|P53778|MK12_HUMAN,sp|O15264|MK13_HUMAN,sp|P45983|MK08_HUMAN,sp|Q16539|MK14_HUMAN,sp|P45984|MK09_HUMAN,sp|Q15759|MK11_HUMAN,sp|P53779|MK10_HUMAN,sp|Q15746|MYLK_HUMAN,tr|A0A286YFD7|A0A286YFD7_HUMAN,tr|A0A286YES0|A0A286YES0_HUMAN,tr|A0A286YEQ0|A0A286YEQ0_HUMAN,tr|A0A286YEX7|A0A286YEX7_HUMAN,tr|A0A286YFC0|A0A286YFC0_HUMAN,tr|B5MDL5|B5MDL5_HUMAN,tr|A0A286YES9|A0A286YES9_HUMAN,tr|A0A286YF97|A0A286YF97_HUMAN,tr|D6RCB1|D6RCB1_HUMAN,tr|A0A286YF19|A0A286YF19_HUMAN,tr|A0A286YFN2|A0A286YFN2_HUMAN,tr|D6RJF9|D6RJF9_HUMAN,tr|A0A286YEY0|A0A286YEY0_HUMAN,tr|Q5R3E6|Q5R3E6_HUMAN,tr|A0A286YEV8|A0A286YEV8_HUMAN,tr|B4E0K5|B4E0K5_HUMAN,tr|A0A286YF85|A0A286YF85_HUMAN,tr|A0A286YFI3|A0A286YFI3_HUMAN,tr|F8W9R5|F8W9R5_HUMAN,tr|A0A2R8Y4U5|A0A2R8Y4U5_HUMAN,tr|A0A286YFM6|A0A286YFM6_HUMAN,tr|A0A286YEV3|A0A286YEV3_HUMAN,tr|A0A286YF83|A0A286YF83_HUMAN,tr|A0A286YFJ6|A0A286YFJ6_HUMAN,tr|A0A286YF62|A0A286YF62_HUMAN,tr|A0A286YF02|A0A286YF02_HUMAN,tr|J3KNK1|J3KNK1_HUMAN,tr|A0A286YEQ7|A0A286YEQ7_HUMAN,tr|A0A286YFJ4|A0A286YFJ4_HUMAN,tr|A0A1W2PPZ3|A0A1W2PPZ3_HUMAN,tr|A0A286YEN5|A0A286YEN5_HUMAN,tr|A0A286YFA6|A0A286YFA6_HUMAN,tr|A0A1P0B7D2|A0A1P0B7D2_HUMAN,tr|A0A1W2PRF2|A0A1W2PRF2_HUMAN,tr|D7R525|D7R525_HUMAN,tr|A0A286YF35|A0A286YF35_HUMAN,tr|A0A286YFB6|A0A286YFB6_HUMAN,tr|A0A286YFE2|A0A286YFE2_HUMAN,tr|A0A286YEW9|A0A286YEW9_HUMAN,tr|E7EX54|E7EX54_HUMAN" 51 903.5178 3.7 13805 17578 2 903.519193 452.7662 Myosin light chain kinase family member 4 OS=Homo sapiens OX=9606 GN=MYLK4 PE=1 SV=2 5.84 3468.3 - 506263 - - - 1.5395 - 1.992 0.062 - 219.2 1 2 0 0.0014 8 0 0 0 3.80E+07 1.03E+07 - - - 1.5769 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.17582.17582.2 0.000945 16-Aug K.ALQFLEEVK.V sp|P40227|TCPZ_HUMAN 1 1075.5914 32.27 13808 17582 2 1075.591833 538.803 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 3468.7 - 1.03E+06 - - - 0.4388 - 1.729 0.327 - 198.6 1 2 0 0.0005 9 0 0 0 4.85E+07 1.50E+06 - - - 3.0401 1 230117_WJC_METTL3_WT_vs_EV_F02.17589.17589.2 4.77E-06 14/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 4.7 13812 17589 2 1484.910843 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3469.5 - 1.69E+06 - - - 1.992 - 2.454 0.545 - 492.9 1 2 0 0.003 15 0 0 0 4.22E+07 8.99E+06 - - - 5.2725 0.9789 230117_WJC_METTL3_WT_vs_EV_F02.17596.17596.2 0.0314 14-Jun R.GLFIIDGK.G sp|P32119|PRDX2_HUMAN 1 861.496 2.37 13816 17596 2 861.493009 431.7553 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3470.5 - 1.57E+06 - - - -3.4765 - 1.415 0.244 - 129.7 1 2 0 -0.003 8 0 0 0 3.12E+08 1.31E+08 - - - 1.8892 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17598.17598.2 8.47E-05 20-Oct K.FSPAGPILSIR.L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1156.6604 1.03 13818 17598 2 1156.660705 579.3375 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3470.7 - 5.54E+06 - - - 0.2256 - 1.993 0.348 - 411.1 1 2 0 0.0003 11 0 0 0 7.11E+08 6.90E+08 - - - 3.4769 1 230117_WJC_METTL3_WT_vs_EV_F02.17599.17599.2 8.80E-06 18-Dec K.VGDQILLAIK.G sp|Q6P1L8|RM14_HUMAN 1 1068.6543 1.63 13819 17599 2 1068.650129 535.3344 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3470.9 - 1.67E+06 - - - -3.8993 - 2.493 0.498 - 453.9 1 2 0 -0.0042 10 0 0 0 8.31E+07 5.10E+07 - - - 5.2677 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.17605.17605.2 0.00167 14-Aug R.GLFIIDGK[136.11].G sp|P32119|PRDX2_HUMAN 1 869.5102 2.37 13822 17605 2 869.508459 435.7624 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3471.7 - 1.32E+06 - - - -2.0069 - 1.508 0.388 - 278.4 1 2 0 -0.0017 8 0 0 0 3.12E+08 1.31E+08 - - - 3.1451 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.17606.17606.2 0.541 14-Aug K.IIDFGLAR[166.11].R "sp|Q86YV6|MYLK4_HUMAN,sp|Q32MK0|MYLK3_HUMAN,sp|Q9H1R3|MYLK2_HUMAN,sp|P53778|MK12_HUMAN,sp|O15264|MK13_HUMAN,sp|P45983|MK08_HUMAN,sp|Q16539|MK14_HUMAN,sp|P45984|MK09_HUMAN,sp|Q15759|MK11_HUMAN,sp|P53779|MK10_HUMAN,sp|Q15746|MYLK_HUMAN,tr|A0A286YFD7|A0A286YFD7_HUMAN,tr|A0A286YES0|A0A286YES0_HUMAN,tr|A0A286YEQ0|A0A286YEQ0_HUMAN,tr|A0A286YEX7|A0A286YEX7_HUMAN,tr|A0A286YFC0|A0A286YFC0_HUMAN,tr|B5MDL5|B5MDL5_HUMAN,tr|A0A286YES9|A0A286YES9_HUMAN,tr|A0A286YF97|A0A286YF97_HUMAN,tr|D6RCB1|D6RCB1_HUMAN,tr|A0A286YF19|A0A286YF19_HUMAN,tr|A0A286YFN2|A0A286YFN2_HUMAN,tr|D6RJF9|D6RJF9_HUMAN,tr|A0A286YEY0|A0A286YEY0_HUMAN,tr|Q5R3E6|Q5R3E6_HUMAN,tr|A0A286YEV8|A0A286YEV8_HUMAN,tr|B4E0K5|B4E0K5_HUMAN,tr|A0A286YF85|A0A286YF85_HUMAN,tr|A0A286YFI3|A0A286YFI3_HUMAN,tr|F8W9R5|F8W9R5_HUMAN,tr|A0A2R8Y4U5|A0A2R8Y4U5_HUMAN,tr|A0A286YFM6|A0A286YFM6_HUMAN,tr|A0A286YEV3|A0A286YEV3_HUMAN,tr|A0A286YF83|A0A286YF83_HUMAN,tr|A0A286YFJ6|A0A286YFJ6_HUMAN,tr|A0A286YF62|A0A286YF62_HUMAN,tr|A0A286YF02|A0A286YF02_HUMAN,tr|J3KNK1|J3KNK1_HUMAN,tr|A0A286YEQ7|A0A286YEQ7_HUMAN,tr|A0A286YFJ4|A0A286YFJ4_HUMAN,tr|A0A1W2PPZ3|A0A1W2PPZ3_HUMAN,tr|A0A286YEN5|A0A286YEN5_HUMAN,tr|A0A286YFA6|A0A286YFA6_HUMAN,tr|A0A1P0B7D2|A0A1P0B7D2_HUMAN,tr|A0A1W2PRF2|A0A1W2PRF2_HUMAN,tr|D7R525|D7R525_HUMAN,tr|A0A286YF35|A0A286YF35_HUMAN,tr|A0A286YFB6|A0A286YFB6_HUMAN,tr|A0A286YFE2|A0A286YFE2_HUMAN,tr|A0A286YEW9|A0A286YEW9_HUMAN,tr|E7EX54|E7EX54_HUMAN" 51 913.5261 3.72 13823 17606 2 913.529025 457.7703 Myosin light chain kinase family member 4 OS=Homo sapiens OX=9606 GN=MYLK4 PE=1 SV=2 5.84 3471.8 - 602076 - - - 3.2325 - 1.789 0.279 - 140.9 1 2 0 0.003 8 0 0 0 3.78E+07 1.02E+07 - - - 2.855 0.9295 230117_WJC_METTL3_WT_vs_EV_F02.17607.17607.2 0.0477 18-Oct D.TLDNDIMLIK.L "sp|P35030|TRY3_HUMAN,tr|A0A7P0MNE9|A0A7P0MNE9_HUMAN" 2 1174.6268 90.06 13824 17607 2 1174.631081 588.3207 Trypsin-3 OS=Homo sapiens OX=9606 GN=PRSS3 PE=1 SV=2 4.21 3471.9 - 1.95E+06 - - - 3.6778 - 1.941 0.403 - 216.9 1 1 0 0.0043 10 0 0 0 9.22E+07 1.02E+06 - - - 3.8674 0.9768 230117_WJC_METTL3_WT_vs_EV_F02.17608.17608.2 1.2 12-May K.QFLLLSR.Q sp|Q5T447|HECD3_HUMAN 1 875.5229 3 13825 17608 2 875.52202 438.7687 E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens OX=9606 GN=HECTD3 PE=1 SV=1 9.75 3472 - 390843 - - - -0.9914 - 1.394 0.119 - 73.6 8 2 0 -0.0009 7 0 0 0 8.25E+06 2.75E+06 - - - 0.5688 0.9226 230117_WJC_METTL3_WT_vs_EV_F02.17609.17609.2 0.00389 28-Jul R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 6.36 13826 17609 2 1494.904512 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3472.1 - 0 - - - -7.7884 - 1.735 0.379 - 107.9 1 2 0 -0.0116 15 0 0 0 6.54E+07 1.03E+07 - - - 3.1913 0.9628 230117_WJC_METTL3_WT_vs_EV_F02.17613.17613.2 0.000338 26-Sep R.GLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1541.7726 - 13828 17613 2 1541.772427 771.8936 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3472.6 - 838608 - - - -0.0947 - 1.989 0.441 - 86.5 1 1 0 -0.0001 14 0 0 0 - - - - - 4.0238 0.9957 230117_WJC_METTL3_WT_vs_EV_F02.17616.17616.2 1.84 12-Jul K.SLDIFIK.A sp|Q9H583|HEAT1_HUMAN 1 834.4851 0.4 13831 17616 2 834.48698 418.2498 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.55 3473 - 477607 - - - 2.2469 - 1.333 0.176 - 171.6 1 2 0 0.0019 7 0 0 0 8.35E+06 2.08E+07 - - - 1.2511 1 230117_WJC_METTL3_WT_vs_EV_F02.17617.17617.2 2.08E-06 13/20 K.VLADLAIYEPK[136.11].T sp|Q9BYC9|RM20_HUMAN 1 1238.7002 1.1 13832 17617 2 1238.707353 620.3574 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3473.2 - 433450 - - - 5.7827 - 2.437 0.438 - 519.7 1 2 0 0.0072 11 0 0 0 1.72E+07 1.56E+07 - - - 4.6836 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17621.17621.2 0.0185 16-Dec R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 0.87 13834 17621 2 997.606516 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3473.6 - 4.96E+06 - - - 1.3522 - 2.496 0.382 - 367.5 1 2 0 0.0013 9 0 0 0 1.80E+08 2.08E+08 - - - 4.5083 0.9951 230117_WJC_METTL3_WT_vs_EV_F02.17622.17622.2 0.39 12-Jul K.FIPEFIR.K "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|A0A804HIK9|A0A804HIK9_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 5 920.512 14.55 13835 17622 2 920.511728 461.2633 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6 3473.7 - 747257 - - - -0.2835 - 1.339 0.198 - 172.7 1 2 0 -0.0003 7 0 0 0 7.10E+08 4.88E+07 - - - 1.4283 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.17623.17623.2 0.000386 18-Sep K.VGDQILLAIK[136.11].G sp|Q6P1L8|RM14_HUMAN 1 1076.6685 1.63 13836 17623 2 1076.667337 539.3415 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3473.8 - 3.93E+06 - - - -1.0765 - 1.856 0.393 - 189.8 1 2 0 -0.0012 10 0 0 0 8.31E+07 5.10E+07 - - - 3.6695 0.9869 230117_WJC_METTL3_WT_vs_EV_F02.17624.17624.2 0.0253 16-Sep K.FLLENSVLK.M "sp|Q92696|PGTA_HUMAN,tr|H0YMG5|H0YMG5_HUMAN,tr|H0YKZ8|H0YKZ8_HUMAN,tr|H0YLG7|H0YLG7_HUMAN" 4 1061.6121 14.9 13837 17624 2 1061.609395 531.8133 Geranylgeranyl transferase type-2 subunit alpha OS=Homo sapiens OX=9606 GN=RABGGTA PE=1 SV=2 6 3473.9 - 3.03E+06 - - - -2.5452 - 1.64 0.18 - 211.4 1 2 0 -0.0027 9 0 0 0 2.06E+07 1.38E+06 - - - 1.8008 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.17626.17626.2 0.348 12-Aug K.SLDIFIK[136.11].A sp|Q9H583|HEAT1_HUMAN 1 842.4993 0.65 13839 17626 2 842.499469 422.2569 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.55 3474.2 - 1.08E+06 - - - 0.1947 - 1.269 0.262 - 182.8 1 2 0 0.0002 7 0 0 0 1.60E+07 2.45E+07 - - - 1.7309 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17631.17631.2 0.083 16-Sep R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.88 13843 17631 2 989.592506 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3474.8 - 2.20E+06 - - - 1.5552 - 2.069 0.304 - 218.7 1 2 0 0.0015 9 0 0 0 1.73E+08 1.97E+08 - - - 3.3893 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17632.17632.2 0.000305 18-Oct R.FQSLGVAFYR.G "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1186.6135 1.27 13844 17632 2 1186.613242 594.314 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 8.75 3474.9 - 1.10E+06 - - - -0.2124 - 2.008 0.468 - 306.4 1 2 0 -0.0003 10 0 0 0 4.72E+07 3.72E+07 - - - 4.4435 0.9868 230117_WJC_METTL3_WT_vs_EV_F02.17633.17633.2 0.228 12-May K.FIPEFIR[166.11].K "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|A0A804HIK9|A0A804HIK9_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 5 930.5203 14.91 13845 17633 2 930.521638 466.2674 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6 3474.9 - 450411 - - - 1.482 - 1.051 0.147 - 77.1 1 2 0 0.0014 7 0 0 0 7.08E+08 4.75E+07 - - - 0.2839 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17635.17635.2 0.000303 18-Oct K.LLYPLQEVER.F "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 1258.6921 0.79 13847 17635 2 1258.693491 630.3533 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.53 3475.2 - 357182 - - - 1.0749 - 1.95 0.376 - 426.4 1 2 0 0.0014 10 0 0 0 5.99E+06 7.56E+06 - - - 3.6818 1 230117_WJC_METTL3_WT_vs_EV_F02.17639.17639.2 5.49E-09 18-Nov K.LGDDIDLIVR.C sp|O15371|EIF3D_HUMAN 1 1127.6186 1.1 13849 17639 2 1127.616798 564.8166 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3475.8 - 2.12E+06 - - - -1.6326 - 2.449 0.438 - 351.7 1 2 0 -0.0018 10 0 0 0 2.35E+08 2.13E+08 - - - 4.7756 0.9716 230117_WJC_METTL3_WT_vs_EV_F02.17641.17641.2 0.00214 14-Aug R.GLFIIDDK[136.11].G "sp|Q06830|PRDX1_HUMAN,sp|Q13162|PRDX4_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|H7C3T4|H7C3T4_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 5 927.5157 2.2 13851 17641 2 927.513824 464.7651 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.21 3475.9 - 1.16E+06 - - - -2.0054 - 1.834 0.002 - 261.1 1 2 0 -0.0019 8 0 0 0 1.43E+09 6.51E+08 - - - 0.8844 0.9718 230117_WJC_METTL3_WT_vs_EV_F02.17645.17645.2 0.144 16-Mar R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 9946.69 13854 17645 2 1006.569916 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3476.4 - 2.84E+08 - - - 0.0179 - 0.686 0.28 - 26.5 1 2 0 0 9 0 0 0 2.31E+11 2.32E+07 - - - 0.0187 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.17648.17648.2 0.289 18-Oct K.ALLAEGVILR.R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1053.6546 1.39 13856 17648 2 1053.657357 527.8346 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3476.7 - 820484 - - - 2.5881 - 1.961 0.143 - 271.2 1 2 0 0.0027 10 0 0 0 2.55E+08 1.83E+08 - - - 1.9762 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.17650.17650.2 0.00125 20-Dec K.VLADLAIYEPK.T sp|Q9BYC9|RM20_HUMAN 1 1230.686 1.1 13858 17650 2 1230.685341 616.3503 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3477 - 507084 - - - -0.5273 - 2.095 0.338 - 323.6 1 2 0 -0.0006 11 0 0 0 1.72E+07 1.56E+07 - - - 3.5379 0.9834 230117_WJC_METTL3_WT_vs_EV_F02.17654.17654.2 0.575 12-Jul K.ITWSIIR[166.11].E sp|P38606|VATA_HUMAN 1 897.5312 1.11 13862 17654 2 897.535927 449.7729 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 9.75 3477.5 - 357320 - - - 5.3135 - 1.561 0.175 - 135.2 1 2 0 0.0048 7 0 0 0 1.03E+07 9.29E+06 - - - 1.7431 0.998 230117_WJC_METTL3_WT_vs_EV_F02.17655.17655.2 0.000634 18-Aug K.LLYPLQEVER[166.11].F "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 1268.7004 0.76 13863 17655 2 1268.705734 635.3575 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.53 3477.6 - 322957 - - - 4.198 - 1.7 0.367 - 255.7 1 2 0 0.0053 10 0 0 0 6.08E+06 8.04E+06 - - - 3.2311 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.17657.17657.2 0.022 16-Sep R.ITELMQVLK[136.11].D "sp|P28288|ABCD3_HUMAN,tr|A0A3B3ITW3|A0A3B3ITW3_HUMAN" 2 1081.6297 0.73 13865 17657 2 1081.633744 541.8221 ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3 PE=1 SV=1 6 3477.9 - 208748 - - - 3.7684 - 1.916 0.234 - 133.9 1 2 0 0.0041 9 0 0 0 5.82E+06 8.01E+06 - - - 2.6492 1 230117_WJC_METTL3_WT_vs_EV_F02.17658.17658.2 0.000235 20-Nov R.LLYC[160.03]TTGVLLR.R "sp|Q6P158|DHX57_HUMAN,sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 3 1307.7271 0.6 13866 17658 2 1307.730674 654.8708 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 8.22 3478 - 140940 - - - 2.6993 - 2.252 0.488 - 546.6 1 2 0 0.0035 11 0 0 0 7.61E+06 1.27E+07 - - - 4.8404 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.17662.17662.2 0.263 18-Nov K.ALLAEGVILR[166.11].R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1063.6629 1.39 13869 17662 2 1063.663578 532.8387 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3478.3 - 3.46E+06 - - - 0.6374 - 1.849 0.157 - 559.7 1 2 0 0.0007 10 0 0 0 2.55E+08 1.83E+08 - - - 1.9161 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.17664.17664.2 0.0192 12-Jul R.IIFDDFR[166.11].E sp|P46977|STT3A_HUMAN 1 934.4788 1.16 13871 17664 2 934.479071 468.2467 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.21 3478.4 - 818823 - - - 0.3028 - 1.154 0.3 - 155.4 1 2 0 0.0003 7 0 0 0 1.20E+08 1.04E+08 - - - 1.7106 1 230117_WJC_METTL3_WT_vs_EV_F02.17666.17666.2 5.83E-05 20-Sep K.VYGAILVAVER.L sp|Q9Y6J9|TAF6L_HUMAN 1 1188.6867 0.88 13873 17666 2 1188.68648 595.3506 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 5.97 3478.5 - 664571 - - - -0.1506 - 1.902 0.523 - 254.8 1 2 0 -0.0002 11 0 0 0 2.30E+07 2.61E+07 - - - 4.643 0.9901 230117_WJC_METTL3_WT_vs_EV_F02.17667.17667.2 0.996 12-Jun K.DFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 834.46 0.87 13874 17667 2 834.459904 418.2373 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.84 3478.6 - 378231 - - - -0.0587 - 1.361 0.103 - 124.1 1 2 0 0 7 0 0 0 9.61E+06 1.10E+07 - - - 0.7784 0.998 230117_WJC_METTL3_WT_vs_EV_F02.17670.17670.2 0.476 14-Oct R.NLLTGLVR.H "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 884.5444 1.28 13875 17670 2 884.544218 443.2795 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 9.75 3479 - 1.17E+06 - - - -0.1504 - 1.465 0.267 - 323.5 1 2 0 -0.0001 8 0 0 0 1.50E+08 1.17E+08 - - - 2.1647 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17671.17671.2 7.53E-05 20-Oct R.LLYC[160.03]TTGVLLR[166.11].R "sp|Q6P158|DHX57_HUMAN,sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 3 1317.7354 0.6 13876 17671 2 1317.736536 659.875 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 8.22 3479.2 - 715070 - - - 0.8515 - 1.938 0.436 - 427.5 1 2 0 0.0011 11 0 0 0 7.61E+06 1.27E+07 - - - 4.0509 0.9908 230117_WJC_METTL3_WT_vs_EV_F02.17673.17673.2 0.484 14-Jul K.TTQLLFLK[136.11].A sp|O94874|UFL1_HUMAN 1 970.5943 2.78 13878 17673 2 970.595854 486.3044 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 8.41 3479.4 - 502853 - - - 1.6341 - 1.269 0.106 - 121.8 1 2 0 0.0016 8 0 0 0 1.61E+07 5.80E+06 - - - 0.5419 0.9834 230117_WJC_METTL3_WT_vs_EV_F02.17674.17674.2 0.467 14-Aug K.ISALALLK[136.11].M sp|Q92905|CSN5_HUMAN 1 835.5622 1.59 13879 17674 2 835.561245 418.7884 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 8.75 3479.5 - 309735 - - - -1.1908 - 1.39 0.118 - 109.6 1 2 0 -0.001 8 0 0 0 2.52E+07 1.58E+07 - - - 0.9054 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.17675.17675.2 0.97 14-Aug K.ISALALLK.M sp|Q92905|CSN5_HUMAN 1 827.548 1.59 13880 17675 2 827.549054 414.7813 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 8.75 3479.7 - 289066 - - - 1.2253 - 1.902 0.188 - 97.4 2 2 0 0.001 8 0 0 0 2.52E+07 1.58E+07 - - - 2.2338 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17679.17679.2 0.0334 16-Oct R.LNVLANVIR[166.11].K "sp|Q02218|ODO1_HUMAN,sp|Q9ULD0|OGDHL_HUMAN,tr|E9PFG7|E9PFG7_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|A0A0D9SFS3|A0A0D9SFS3_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 6 1020.6319 0.96 13882 17679 2 1020.632992 511.3232 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 9.75 3480.2 - 604505 - - - 1.0366 - 2.164 0.267 - 293.3 1 2 0 0.0011 9 0 0 0 1.32E+07 1.38E+07 - - - 3.246 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17680.17680.2 0.0098 18-Oct R.IAEFAFEYAR.N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1215.5924 2.6 13883 17680 2 1215.593206 608.8035 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3480.3 - 1.24E+06 - - - 0.6433 - 2.358 0.252 - 371.8 1 2 0 0.0008 10 0 0 0 3.29E+07 1.26E+07 - - - 3.2964 0.9943 230117_WJC_METTL3_WT_vs_EV_F02.17683.17683.2 0.0162 18-Aug R.LPLLAVC[160.03]DYK.Q "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1190.6369 0.66 13886 17683 2 1190.635644 596.3257 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.83 3480.6 - 509178 - - - -1.0818 - 1.379 0.241 - 162 1 2 0 -0.0013 10 0 0 0 5.21E+06 7.86E+06 - - - 1.7176 1 230117_WJC_METTL3_WT_vs_EV_F02.17684.17684.2 4.07E-06 13/22 K.TPAILYTYSGLR.N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1353.7293 2.41 13887 17684 2 1353.732232 677.8719 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3480.8 - 383749 - - - 2.2013 - 2.667 0.494 - 692.1 1 2 0 0.003 12 0 0 0 1.51E+07 6.28E+06 - - - 5.2698 0.9881 230117_WJC_METTL3_WT_vs_EV_F02.17685.17685.2 2.85 12-Jun R.LLPAFLK.V sp|Q9NW08|RPC2_HUMAN 1 800.516 0.84 13888 17685 2 800.516841 401.2653 DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2 8.75 3480.9 - 353909 - - - 1.0368 - 1.085 0.144 - 88.5 1 2 0 0.0008 7 0 0 0 3.94E+06 4.69E+06 - - - 0.3628 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17691.17691.2 0.14 20-Dec R.ELLIIGGVAAR.D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1110.6761 1.12 13892 17691 2 1110.676981 556.3453 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3481.6 - 690162 - - - 0.7986 - 2.486 0.282 - 386.3 1 2 0 0.0009 11 0 0 0 2.84E+08 2.54E+08 - - - 3.5872 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17693.17693.2 0.0096 20-Jul R.ELLIIGGVAAR[166.11].D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1120.6844 1.13 13894 17693 2 1120.68483 561.3495 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3481.9 - 585536 - - - 0.4158 - 1.857 0.343 - 119.6 1 2 0 0.0005 11 0 0 0 2.84E+08 2.51E+08 - - - 3.2487 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.17694.17694.2 0.00344 18-Nov R.IAEFAFEYAR[166.11].N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1225.6007 2.6 13895 17694 2 1225.600582 613.8076 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3482 - 552971 - - - -0.0914 - 2.196 0.239 - 425.7 1 2 0 -0.0001 10 0 0 0 3.29E+07 1.26E+07 - - - 3.002 0.9939 230117_WJC_METTL3_WT_vs_EV_F02.17696.17696.2 0.00586 22-Jul R.LPVPESITGFAR.L "sp|Q8N5K1|CISD2_HUMAN,tr|I3L1N9|I3L1N9_HUMAN,tr|A0A2R8Y540|A0A2R8Y540_HUMAN" 3 1285.703 0.9 13897 17696 2 1285.702443 643.8588 CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1 6 3482.3 - 317269 - - - -0.462 - 1.597 0.143 - 102.3 1 2 0 -0.0006 12 0 0 0 4.21E+06 4.70E+06 - - - 1.3287 1 230117_WJC_METTL3_WT_vs_EV_F02.17698.17698.2 0.39 13/22 K.TPAILYTYSGLR[166.11].N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1363.7375 2.41 13899 17698 2 1363.736084 682.876 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3482.5 - 288192 - - - -1.0545 - 2.963 0.4 - 702 1 2 0 -0.0014 12 0 0 0 1.51E+07 6.28E+06 - - - 4.8529 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17706.17706.2 0.000357 14-Sep K.LMWIPDTK.G sp|P61962|DCAF7_HUMAN 1 1002.5208 1.79 13905 17706 2 1002.523066 502.2677 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.84 3483.5 - 1.44E+06 - - - 2.2214 - 1.678 0.389 - 310.2 1 2 0 0.0022 8 0 0 0 5.28E+07 2.94E+07 - - - 3.4745 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17711.17711.2 0.000811 22-Dec K.LPVGTTATLYFR.D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1337.7343 1.3 13910 17711 2 1337.735535 669.8744 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3484.2 - 185518 - - - 0.8955 - 2.174 0.453 - 352.4 1 2 0 0.0012 12 0 0 0 1.50E+07 1.15E+07 - - - 4.4298 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17715.17715.2 0.000281 14-Aug K.GFGFGLVK[136.11].L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 831.4734 1.14 13912 17715 2 831.474652 416.744 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3484.7 - 2.06E+06 - - - 1.4757 - 1.345 0.45 - 212.9 1 2 0 0.0012 8 0 0 0 2.42E+08 2.13E+08 - - - 3.2582 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17719.17719.2 0.000347 22-Oct K.LPVGTTATLYFR[166.11].D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1347.7426 1.3 13916 17719 2 1347.74568 674.8786 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3485.1 - 503606 - - - 2.2801 - 2.053 0.408 - 171.8 1 2 0 0.0031 12 0 0 0 1.50E+07 1.15E+07 - - - 3.9461 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.17720.17720.2 0.00187 20-Sep K.VLVIGELGVGK.T sp|Q13637|RAB32_HUMAN 1 1082.6699 1.33 13917 17720 2 1082.673465 542.3422 Ras-related protein Rab-32 OS=Homo sapiens OX=9606 GN=RAB32 PE=1 SV=3 5.97 3485.2 - 449017 - - - 3.2503 - 1.982 0.429 - 137.1 1 2 0 0.0035 11 0 0 0 5.56E+06 4.17E+06 - - - 4.0592 0.9896 230117_WJC_METTL3_WT_vs_EV_F02.17724.17724.2 0.486 16-Aug R.LIDFLESGK.T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1020.5492 1.48 13919 17724 2 1020.552096 511.2819 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3485.7 - 193124 - - - 2.8749 - 1.171 0.179 - 132.8 1 2 0 0.0029 9 0 0 0 1.37E+08 9.24E+07 - - - 0.8189 0.991 230117_WJC_METTL3_WT_vs_EV_F02.17727.17727.2 4.83 12-Jul K.FIGELFK[136.11].L "sp|O43432|IF4G3_HUMAN,sp|Q04637|IF4G1_HUMAN,tr|A0A804HJV5|A0A804HJV5_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|A0A0U1RQK7|A0A0U1RQK7_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|A0A0A0MSA7|A0A0A0MSA7_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 11 860.4887 1.31 13920 17727 2 860.489129 431.2516 Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2 6 3486.1 - 636438 - - - 0.4509 - 1.246 0.126 - 118.1 1 2 0 0.0004 7 0 0 0 6.27E+07 4.78E+07 - - - 0.6684 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17728.17728.2 0.00129 18-Oct K.ILETLYTLGK.A "sp|Q5W0V3|FHI2A_HUMAN,tr|Q5W0V4|Q5W0V4_HUMAN" 2 1149.6645 999 13921 17728 2 1149.665883 575.8395 FHF complex subunit HOOK interacting protein 2A OS=Homo sapiens OX=9606 GN=FHIP2A PE=1 SV=1 6 3486.2 - 190913 - - - 1.1803 - 1.98 0.4 - 219 1 2 0 0.0014 10 0 0 0 6.54E+06 0.00E+00 - - - 3.9017 0.9908 230117_WJC_METTL3_WT_vs_EV_F02.17732.17732.2 0.0284 14-Aug K.TILSLMTR[166.11].E sp|P53396|ACLY_HUMAN 1 943.54 1.07 13923 17732 2 943.544301 472.7773 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.41 3486.8 - 1.04E+06 - - - 4.5499 - 1.517 0.206 - 191.6 1 2 0 0.0043 8 0 0 0 5.03E+07 4.71E+07 - - - 1.818 0.998 230117_WJC_METTL3_WT_vs_EV_F02.17740.17740.2 0.322 16-Sep K.IAFAITAIK[136.11].G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 954.5994 1.19 13930 17740 2 954.602242 478.307 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3487.8 - 2.01E+06 - - - 3.0254 - 1.835 0.205 - 136.9 1 2 0 0.0029 9 0 0 0 5.16E+09 4.34E+09 - - - 2.3104 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17744.17744.2 0.000471 14-Aug K.GFGFGLVK.L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 823.4592 1.14 13933 17744 2 823.459458 412.7369 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3488.1 - 6.75E+06 - - - 0.283 - 1.513 0.446 - 212.9 1 2 0 0.0002 8 0 0 0 2.42E+08 2.12E+08 - - - 3.584 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.17747.17747.2 0.0485 16-Aug K.VNIIPIIAK[136.11].A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 987.6572 1.04 13936 17747 2 987.659116 494.8359 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3488.3 - 1.15E+06 - - - 1.9369 - 1.37 0.238 - 188.5 1 2 0 0.0019 9 0 0 0 4.85E+07 4.65E+07 - - - 1.709 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.17749.17749.2 0.144 12-Jul K.GVIFYLR.D "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 9 866.5014 3.42 13938 17749 2 866.501956 434.258 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 8.75 3488.6 - 542090 - - - 0.614 - 1.571 0.158 - 164.7 1 2 0 0.0005 7 0 0 0 3.77E+07 1.10E+07 - - - 1.6391 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.17752.17752.2 0.0082 16-Jul K.VNIIPIIAK.A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 979.643 1.04 13939 17752 2 979.643869 490.8288 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3489 - 764610 - - - 0.884 - 1.316 0.303 - 160.4 1 2 0 0.0009 9 0 0 0 4.85E+07 4.65E+07 - - - 2.0731 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.17753.17753.2 0.349 16-Jun R.AVDVGAFLR[166.11].D "sp|Q96BT3|CENPT_HUMAN,tr|H3BUW2|H3BUW2_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 3 956.5319 0.92 13940 17753 2 956.532579 479.2732 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 5.88 3489 - 686625 - - - 0.7245 - 1.484 0.194 - 93.3 1 2 0 0.0007 9 0 0 0 2.95E+07 3.19E+07 - - - 1.6157 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17758.17758.2 0.00184 16-Aug K.FPTLWSGAR[166.11].S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1043.5428 1.02 13943 17758 2 1043.544683 522.7787 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 9.75 3489.5 - 1.31E+06 - - - 1.8188 - 1.551 0.362 - 174 1 2 0 0.0019 9 0 0 0 4.50E+07 4.43E+07 - - - 2.9839 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.17759.17759.2 0.0524 16-Sep R.LAVLPYELR.F "sp|Q9ULX3|NOB1_HUMAN,tr|H3BUR4|H3BUR4_HUMAN" 2 1072.6281 1.13 13944 17759 2 1072.630863 537.3213 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 6 3489.6 - 974146 - - - 2.5936 - 2.04 0.217 - 396.6 1 2 0 0.0028 9 0 0 0 1.10E+08 9.73E+07 - - - 2.7055 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17767.17767.2 0.0514 20-Oct K.SEIEYYAMLAK[136.11].T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1324.6464 0.89 13950 17767 2 1324.646951 663.3305 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3490.8 - 699352 - - - 0.3858 - 2.017 0.32 - 369.4 1 2 0 0.0005 11 0 0 0 6.99E+06 7.86E+06 - - - 3.3024 1 230117_WJC_METTL3_WT_vs_EV_F02.17768.17768.2 1.31E-05 20-Nov K.SEIEYYAMLAK.T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1316.6322 0.89 13951 17768 2 1316.630423 659.3234 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3490.9 - 552344 - - - -1.38 - 2.305 0.457 - 323.5 1 2 0 -0.0018 11 0 0 0 6.99E+06 7.81E+06 - - - 4.6749 0.999 230117_WJC_METTL3_WT_vs_EV_F02.17770.17770.2 0.00264 18-Sep K.WSEALVLYDR[166.11].V sp|Q9UHB9|SRP68_HUMAN 1 1260.6378 1.58 13953 17770 2 1260.636016 631.3262 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.37 3491.2 - 503971 - - - -1.4215 - 2.118 0.408 - 327.1 1 2 0 -0.0018 10 0 0 0 6.27E+06 3.96E+06 - - - 4.1487 1 230117_WJC_METTL3_WT_vs_EV_F02.17771.17771.2 1.96E-08 13/26 K.NVGLDIEAEVPAVK.D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1452.7824 999 13954 17771 2 1452.782085 727.3985 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 3491.3 - 443040 - - - -0.2237 - 2.489 0.616 - 473 1 2 0 -0.0003 14 0 0 0 4.54E+06 0.00E+00 - - - 5.879 0.9962 230117_WJC_METTL3_WT_vs_EV_F02.17774.17774.2 3.66 14-Jul K.TILSLMTR.E sp|P53396|ACLY_HUMAN 1 933.5317 1.07 13955 17774 2 933.53326 467.7731 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.41 3491.7 - 4.51E+06 - - - 1.6304 - 1.155 0.235 - 132.3 1 2 0 0.0015 8 0 0 0 5.12E+07 4.80E+07 - - - 1.2108 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17775.17775.2 0.00886 12-Jul R.IIFDDFR.E sp|P46977|STT3A_HUMAN 1 924.4705 1.16 13956 17775 2 924.472149 463.2425 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.21 3491.8 - 1.39E+06 - - - 1.7643 - 1.459 0.373 - 152.7 1 2 0 0.0016 7 0 0 0 1.20E+08 1.03E+08 - - - 2.9924 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.17777.17777.2 0.0111 14-Sep K.IYQVLDFR.L "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1052.5655 1.38 13958 17777 2 1052.566675 527.29 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 5.84 3492 - 2.62E+06 - - - 1.1344 - 1.927 0.211 - 335.1 1 2 0 0.0012 8 0 0 0 3.08E+07 2.24E+07 - - - 2.5774 1 230117_WJC_METTL3_WT_vs_EV_F02.17779.17779.2 1.94E-05 18-Nov K.WSEALVLYDR.V sp|Q9UHB9|SRP68_HUMAN 1 1250.6295 1.7 13960 17779 2 1250.632436 626.322 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.37 3492.2 - 821365 - - - 2.3172 - 2.246 0.54 - 450.1 1 2 0 0.0029 10 0 0 0 6.27E+06 3.69E+06 - - - 5.2871 0.9461 230117_WJC_METTL3_WT_vs_EV_F02.17780.17780.2 1.17 14-Oct S.PLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 906.5526 1.28 13961 17780 2 906.552651 454.2836 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 10.18 3492.3 - 782996 - - - 0.0331 - 2.092 0.267 - 404.4 1 1 0 0 8 0 0 0 5.94E+07 4.65E+07 - - - 3.2392 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.17781.17781.2 0.00334 20-Aug R.VLSTDVDVILR.K sp|Q9NUJ1|ABHDA_HUMAN 1 1228.7027 16.31 13962 17781 2 1228.707675 615.3586 "Palmitoyl-protein thioesterase ABHD10, mitochondrial OS=Homo sapiens OX=9606 GN=ABHD10 PE=1 SV=1" 4.21 3492.5 - 729140 - - - 4.0465 - 1.762 0.386 - 141.5 1 2 0 0.005 11 0 0 0 3.50E+06 2.15E+05 - - - 3.4228 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17789.17789.2 0.0754 14-Sep K.IYQVLDFR[166.11].L "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1062.5738 1.3 13968 17789 2 1062.575297 532.2942 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 5.84 3493.5 - 1.20E+06 - - - 1.455 - 1.902 0.266 - 311.3 1 2 0 0.0015 8 0 0 0 3.08E+07 2.36E+07 - - - 2.9442 0.9881 230117_WJC_METTL3_WT_vs_EV_F02.17794.17794.2 0.383 14-Jun R.DILIDPIR[166.11].V "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 963.5629 1.73 13973 17794 2 963.563218 482.7887 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3494.1 - 339032 - - - 0.3798 - 1.159 0.136 - 105.3 1 2 0 0.0004 8 0 0 0 2.58E+07 1.49E+07 - - - 0.4904 0.998 230117_WJC_METTL3_WT_vs_EV_F02.17801.17801.2 0.031 14-Jul R.IGLNLFNK.K "sp|Q6DN90|IQEC1_HUMAN,sp|Q5JU85|IQEC2_HUMAN,tr|A0A0C4DGT3|A0A0C4DGT3_HUMAN,tr|A0A1W2PRJ5|A0A1W2PRJ5_HUMAN,tr|A0A2R8Y7T6|A0A2R8Y7T6_HUMAN,tr|A0A6Q8PFR7|A0A6Q8PFR7_HUMAN,tr|A0A3B3IRZ4|A0A3B3IRZ4_HUMAN,tr|A0A2R8Y695|A0A2R8Y695_HUMAN,tr|A0A3B3IU98|A0A3B3IU98_HUMAN,tr|A0A1W2PR28|A0A1W2PR28_HUMAN" 10 917.5335 2.08 13978 17801 2 917.535045 459.774 IQ motif and SEC7 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=IQSEC1 PE=1 SV=1 8.75 3495.1 - 1.37E+06 - - - 1.7362 - 1.245 0.275 - 106.5 1 2 0 0.0016 8 0 0 0 1.80E+07 8.64E+06 - - - 1.7326 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17802.17802.2 0.00203 20-Nov R.YIVQVSPLGIR.L sp|Q10570|CPSF1_HUMAN 1 1243.7289 1.22 13979 17802 2 1243.729991 622.8717 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3495.2 - 1.50E+06 - - - 0.911 - 2.101 0.428 - 462.1 1 2 0 0.0011 11 0 0 0 2.43E+07 1.99E+07 - - - 4.2103 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.17805.17805.2 0.309 14-Jul R.DILIDPIR.V "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 953.5546 1.73 13982 17805 2 953.555919 477.7846 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3495.5 - 718904 - - - 1.4021 - 1.302 0.267 - 178.8 1 2 0 0.0013 8 0 0 0 2.57E+07 1.49E+07 - - - 1.8086 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.17811.17811.2 1.52 12-Jul R.ISPWLLR[166.11].V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 893.5362 0.33 13986 17811 2 893.536791 447.7754 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3496.3 - 1.06E+06 - - - 0.6133 - 1.423 0.189 - 168.8 1 2 0 0.0005 7 0 0 0 3.39E+07 1.02E+08 - - - 1.5545 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17812.17812.2 0.000128 20-Oct R.YIVQVSPLGIR[166.11].L sp|Q10570|CPSF1_HUMAN 1 1253.7371 1.22 13987 17812 2 1253.738095 627.8758 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3496.4 - 2.79E+06 - - - 0.7713 - 1.732 0.543 - 346.3 1 2 0 0.001 11 0 0 0 2.43E+07 1.99E+07 - - - 4.5372 0.9741 230117_WJC_METTL3_WT_vs_EV_F02.17814.17814.2 0.000771 14-Sep S.PLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 896.5444 1.42 13989 17814 2 896.545166 449.2795 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 10.18 3496.5 - 1.09E+06 - - - 0.909 - 1.877 0.41 - 295.7 1 1 0 0.0008 8 0 0 0 5.07E+07 3.57E+07 - - - 3.9681 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17817.17817.2 2.62E-05 22-Aug R.VFIGNLNTALVK[136.11].K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1295.7693 0.56 13992 17817 2 1295.769713 648.8919 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3496.9 - 691363 - - - 0.3396 - 1.779 0.488 - 154.8 1 2 0 0.0004 12 0 0 0 6.07E+07 1.08E+08 - - - 4.1609 0.9963 230117_WJC_METTL3_WT_vs_EV_F02.17818.17818.2 0.0376 14-Jul R.GIFPVLC[160.03]K[136.11].D "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 940.5296 2.02 13993 17818 2 940.532848 471.2721 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 8.22 3497.1 - 648794 - - - 3.4959 - 1.527 0.226 - 156.8 1 2 0 0.0033 8 0 0 0 5.49E+07 2.71E+07 - - - 1.9859 0.998 230117_WJC_METTL3_WT_vs_EV_F02.17820.17820.2 9.20E-05 22-Oct R.VFIGNLNTALVK.K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1287.7551 0.56 13995 17820 2 1287.761675 644.8848 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3497.3 - 502948 - - - 5.1268 - 2.201 0.453 - 191.5 1 2 0 0.0066 12 0 0 0 6.07E+07 1.08E+08 - - - 4.4605 0.9848 230117_WJC_METTL3_WT_vs_EV_F02.17829.17829.2 0.0201 20-Aug K.FSPAGPILSIR[166.11].L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1166.6687 -1 14003 17829 2 1166.673915 584.3416 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3498.4 - 202450 - - - 4.458 - 1.2 0.243 - 99.8 1 2 0 0.0052 11 0 0 0 0.00E+00 0.00E+00 - - - 1.3274 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.17831.17831.2 0.0966 12-Jun R.ISPWLLR.V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 883.528 0.36 14005 17831 2 883.529055 442.7713 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3498.6 - 1.27E+06 - - - 1.2246 - 1.338 0.158 - 115.7 1 2 0 0.0011 7 0 0 0 3.19E+07 8.91E+07 - - - 1.1303 1 230117_WJC_METTL3_WT_vs_EV_F02.17832.17832.2 2.36E-06 20-Oct R.IVLLDSSLEYK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1278.7071 10.55 14006 17832 2 1278.70967 640.3608 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3498.7 - 1.18E+06 - - - 1.995 - 2.361 0.56 - 283.9 1 2 0 0.0026 11 0 0 0 1.91E+09 1.81E+08 - - - 5.5004 0.941 230117_WJC_METTL3_WT_vs_EV_F02.17835.17835.2 0.314 May-32 R.ASSGGGAGGAAGYAPVK.Y sp|P25067|CO8A2_HUMAN 1 1376.6684 2.58 14009 17835 2 1376.6672 689.3415 Collagen alpha-2(VIII) chain OS=Homo sapiens OX=9606 GN=COL8A2 PE=1 SV=2 8.63 3499.1 - 788434 - - - -0.9022 - 1.181 0.142 - 33.9 24 2 0 -0.0012 17 0 0 0 2.26E+07 8.76E+06 - - - -0.1181 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17836.17836.2 3.23 14-Oct R.IVEVLLIK.D "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 925.6212 1.18 14010 17836 2 925.622765 463.8179 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6 3499.2 - 662211 - - - 1.6854 - 2.106 0.303 - 205.9 1 2 0 0.0016 8 0 0 0 2.16E+07 1.84E+07 - - - 3.5247 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17842.17842.2 0.00767 14-Oct K.WLTLEVC[160.03]R.E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1075.5485 1.65 14014 17842 2 1075.551572 538.7815 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3500 - 8.40E+06 - - - 2.9018 - 1.952 0.418 - 546.1 1 2 0 0.0031 8 0 0 0 9.03E+07 5.47E+07 - - - 4.1446 1 230117_WJC_METTL3_WT_vs_EV_F02.17843.17843.2 0.000249 20-Oct K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 12.05 14015 17843 2 1204.683112 603.3481 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3500 - 1.10E+07 - - - 1.2775 - 2.259 0.541 - 377 1 2 0 0.0015 11 0 0 0 1.51E+09 1.26E+08 - - - 5.2409 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17844.17844.2 0.002 14-Sep K.WLTLEVC[160.03]R[166.11].E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1085.5567 1.64 14016 17844 2 1085.559494 543.7856 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3500.1 - 5.45E+06 - - - 2.5544 - 1.845 0.397 - 444.8 1 2 0 0.0028 8 0 0 0 8.89E+07 5.42E+07 - - - 3.8196 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.17848.17848.2 1.68 14-Aug R.IVEVLLIK[136.11].D "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 933.6354 1.22 14020 17848 2 933.636095 467.825 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6 3500.3 - 2.11E+06 - - - 0.739 - 1.613 0.328 - 125 1 2 0 0.0007 8 0 0 0 2.27E+07 1.86E+07 - - - 2.9053 1 230117_WJC_METTL3_WT_vs_EV_F02.17849.17849.2 0.000177 16-Oct K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 0.9 14021 17849 2 983.577294 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 3500.4 - 1.58E+06 - - - 0.9293 - 2.144 0.495 - 370.7 1 2 0 0.0009 9 0 0 0 2.81E+07 3.11E+07 - - - 4.9032 1 230117_WJC_METTL3_WT_vs_EV_F02.17850.17850.2 1.10E-05 20-Dec K.FATEAAITILR[166.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1214.6898 12.04 14022 17850 2 1214.692302 608.3522 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3500.5 - 1.46E+06 - - - 2.0244 - 2.352 0.556 - 580.1 1 2 0 0.0025 11 0 0 0 1.51E+09 1.26E+08 - - - 5.4605 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.17852.17852.2 0.00122 16-Jul R.FLVQLDDYR.F "sp|Q9HAD4|WDR41_HUMAN,tr|D6RE66|D6RE66_HUMAN,tr|B4DK73|B4DK73_HUMAN,tr|D6RH33|D6RH33_HUMAN,tr|D6RA22|D6RA22_HUMAN,tr|B4DHS8|B4DHS8_HUMAN,tr|D6R9E7|D6R9E7_HUMAN,tr|H0YAA3|H0YAA3_HUMAN,tr|D6RBY6|D6RBY6_HUMAN,tr|H0YAI6|H0YAI6_HUMAN,tr|D6RB94|D6RB94_HUMAN" 11 1167.5924 1.64 14024 17852 2 1167.593109 584.8035 WD repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=WDR41 PE=1 SV=3 4.21 3500.7 - 1.18E+06 - - - 0.5867 - 1.727 0.479 - 173.5 1 2 0 0.0007 9 0 0 0 9.42E+06 5.75E+06 - - - 4.1594 0.9774 230117_WJC_METTL3_WT_vs_EV_F02.17855.17855.2 0.453 14-Jul K.NVFNALIR.L "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 945.5396 1.31 14027 17855 2 945.542693 473.7771 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 9.75 3501 - 763049 - - - 3.2711 - 1.265 0.093 - 146.9 1 2 0 0.0031 8 0 0 0 5.01E+07 3.81E+07 - - - 0.4359 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17860.17860.2 0.00356 18-Sep K.IIQLLDDYPK[136.11].C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1224.6845 1.03 14030 17860 2 1224.684435 613.3495 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3501.7 - 620808 - - - -0.0857 - 2.076 0.453 - 210.3 1 2 0 -0.0001 10 0 0 0 3.98E+08 3.86E+08 - - - 4.4257 0.9673 230117_WJC_METTL3_WT_vs_EV_F02.17864.17864.2 0.00037 20-Sep F.ILFGVYGDVQR.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 1265.6768 1.34 14034 17864 2 1265.676925 633.8457 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 5.84 3502 - 348963 - - - 0.0814 - 1.84 0.463 - 280.9 1 1 0 0.0001 11 0 0 0 1.81E+07 1.35E+07 - - - 4.1102 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17868.17868.3 0.00539 14/40 K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 9.58 14036 17868 3 1204.682893 402.5678 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3502.4 - 1.21E+06 - - - 1.0957 - 2.029 0.318 - 210.5 1 2 0 0.0013 11 0 0 0 4.23E+07 4.41E+06 - - - 4.095 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.17869.17869.2 0.149 12-Jun R.YLNFFTK[136.11].A sp|P12004|PCNA_HUMAN 1 939.4946 1.32 14037 17869 2 939.496431 470.7546 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3502.6 - 995606 - - - 1.9979 - 1.313 0.245 - 107.2 1 2 0 0.0019 7 0 0 0 6.24E+07 4.73E+07 - - - 1.7128 0.9556 230117_WJC_METTL3_WT_vs_EV_F02.17873.17873.2 0.679 14-Jul R.AFFSSYLK[136.11].S "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 969.5051 0.83 14041 17873 2 969.508478 485.7598 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.63 3503 - 297909 - - - 3.4647 - 1.045 0.119 - 103.7 1 2 0 0.0034 8 0 0 0 2.00E+07 2.41E+07 - - - 0.0516 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.17878.17878.2 0.0366 12-Jul R.YLNFFTK.A sp|P12004|PCNA_HUMAN 1 931.4804 1.3 14044 17878 2 931.481958 466.7475 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3503.6 - 1.95E+06 - - - 1.722 - 1.312 0.368 - 145.1 1 2 0 0.0016 7 0 0 0 6.15E+07 4.72E+07 - - - 2.619 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17880.17880.2 0.0161 16-Oct K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 0.89 14046 17880 2 993.586007 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 3503.8 - 1.50E+06 - - - 1.3658 - 2.189 0.287 - 418.3 1 2 0 0.0014 9 0 0 0 2.78E+07 3.11E+07 - - - 3.4269 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17881.17881.2 0.000189 18-Nov R.LMDEAVLALR[166.11].N sp|Q92616|GCN1_HUMAN 1 1139.6248 0.84 14047 17881 2 1139.627639 570.8197 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3503.9 - 1.07E+06 - - - 2.4912 - 2.008 0.442 - 329.1 1 2 0 0.0028 10 0 0 0 1.17E+07 1.39E+07 - - - 4.2506 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.17883.17883.2 0.00151 20-Sep K.ALGYFAVVTGK.G "sp|O60313|OPA1_HUMAN,tr|A0A2R8YD53|A0A2R8YD53_HUMAN,tr|C9JMB8|C9JMB8_HUMAN,tr|A0A2R8YDM2|A0A2R8YDM2_HUMAN,tr|E5KLJ9|E5KLJ9_HUMAN,tr|A0A2R8Y4Q3|A0A2R8Y4Q3_HUMAN,tr|A0A2R8Y3X5|A0A2R8Y3X5_HUMAN,tr|A0A2R8YGE5|A0A2R8YGE5_HUMAN,tr|A0A2R8YFD1|A0A2R8YFD1_HUMAN,tr|A0A2R8YE78|A0A2R8YE78_HUMAN" 10 1124.623 1.9 14049 17883 2 1124.62605 563.3188 "Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3" 8.63 3504.1 - 607437 - - - 2.7156 - 1.698 0.433 - 145 1 2 0 0.0031 11 0 0 0 7.04E+06 3.70E+06 - - - 3.6705 0.9904 230117_WJC_METTL3_WT_vs_EV_F02.17887.17887.2 0.542 12-Aug R.WLITLNK.Q "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 886.5276 1.16 14051 17887 2 886.528248 444.2711 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 8.75 3504.6 - 2.52E+06 - - - 0.6869 - 1.38 0.068 - 271.5 1 2 0 0.0006 7 0 0 0 2.12E+08 1.84E+08 - - - 0.5636 0.8532 230117_WJC_METTL3_WT_vs_EV_F02.17895.17895.2 0.014 14-May E.AAFADNLK.W "sp|Q8IZS8|CA2D3_HUMAN,tr|B4DSF6|B4DSF6_HUMAN" 2 848.4392 0.62 14057 17895 2 848.439905 425.2269 Voltage-dependent calcium channel subunit alpha-2\delta-3 OS=Homo sapiens OX=9606 GN=CACNA2D3 PE=1 SV=1 5.88 3505.6 - 1.36E+06 - - - 0.8097 - 1.378 0.23 - 95.3 1 1 0 0.0007 8 0 0 0 1.66E+07 2.69E+07 - - - 1.7066 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.17896.17896.2 0.00332 14-Jul R.AFFSSYLK.S "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 961.4909 0.83 14058 17896 2 961.491947 481.7527 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.63 3505.7 - 1.39E+06 - - - 1.0692 - 1.276 0.346 - 136.1 1 2 0 0.001 8 0 0 0 2.00E+07 2.40E+07 - - - 2.3313 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.17906.17906.2 0.00415 16-Jul R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 850.03 14067 17906 2 1006.570531 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3506.9 - 3.78E+06 - - - 0.6289 - 1.519 0.33 - 119.2 1 2 0 0.0006 9 0 0 0 1.64E+08 1.93E+05 - - - 2.6876 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.17913.17913.2 0.00638 22-Aug R.IIYVPLPDAATR.R "sp|Q8NB90|AFG2H_HUMAN,tr|A0A6Q8PGU6|A0A6Q8PGU6_HUMAN" 2 1327.75 3.77 14073 17913 2 1327.749213 664.8823 ATPase family protein 2 homolog OS=Homo sapiens OX=9606 GN=SPATA5 PE=1 SV=3 5.84 3507.8 - 597737 - - - -0.5829 - 1.779 0.334 - 200.1 1 2 0 -0.0008 12 0 0 0 4.36E+06 1.16E+06 - - - 3.0234 1 230117_WJC_METTL3_WT_vs_EV_F02.17918.17918.2 0.000518 20-Dec R.YGLIGLNGIGK[136.11].S "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1111.6481 2.71 14076 17918 2 1111.647611 556.8313 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.59 3508.4 - 765367 - - - -0.4354 - 2.255 0.455 - 318.8 1 2 0 -0.0005 11 0 0 0 6.03E+07 2.22E+07 - - - 4.6012 0.9917 230117_WJC_METTL3_WT_vs_EV_F02.17919.17919.2 1.38 14-Jul K.LILTPFER[166.11].N "sp|Q9H089|LSG1_HUMAN,tr|F8WFC6|F8WFC6_HUMAN" 2 997.5836 1.37 14077 17919 2 997.583986 499.7991 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 6 3508.5 - 1.47E+06 - - - 0.4 - 1.348 0.109 - 137.7 1 2 0 0.0004 8 0 0 0 3.57E+07 2.60E+07 - - - 0.7466 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.17921.17921.2 0.00036 16-Sep K.AENPYLFLR.G "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN" 2 1121.5869 1.65 14079 17921 2 1121.586463 561.8007 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 6.05 3508.8 - 781012 - - - -0.4297 - 1.798 0.36 - 295.1 1 2 0 -0.0005 9 0 0 0 8.98E+06 5.45E+06 - - - 3.3971 0.9926 230117_WJC_METTL3_WT_vs_EV_F02.17922.17922.2 0.0199 16-Jun K.AENPYLFLR[166.11].G "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN" 2 1131.5952 1.65 14080 17922 2 1131.593213 566.8049 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 6.05 3508.9 - 651958 - - - -1.7692 - 1.437 0.242 - 87.7 1 2 0 -0.002 9 0 0 0 8.76E+06 5.30E+06 - - - 1.8767 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.17923.17923.2 0.629 18-Aug K.SFIMSSTLIR[166.11].H sp|Q9UEG4|ZN629_HUMAN 1 1163.6248 1.08 14081 17923 2 1163.62482 582.8197 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.47 3509.1 - 368491 - - - 0.0172 - 1.571 0.221 - 196.1 1 2 0 0 10 0 0 0 6.87E+06 6.38E+06 - - - 1.9342 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.17929.17929.2 0.01 14-Sep R.NILIVLTK[136.11].L "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN,tr|H0Y815|H0Y815_HUMAN" 3 920.615 0.87 14086 17929 2 920.61602 461.3148 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 8.75 3509.6 - 364098 - - - 1.1036 - 1.433 0.356 - 194 1 2 0 0.001 8 0 0 0 9.19E+06 1.06E+07 - - - 2.7551 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.17930.17930.2 0.00416 16-Aug K.AAIDWFDGK.E "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1021.4869 1.04 14087 17930 2 1021.490846 511.7507 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.21 3509.7 - 289486 - - - 3.8669 - 1.822 0.388 - 145.5 1 2 0 0.004 9 0 0 0 5.63E+06 5.43E+06 - - - 3.6412 0.9878 230117_WJC_METTL3_WT_vs_EV_F02.17931.17931.2 0.513 18-Jul K.SFIMSSTLIR.H sp|Q9UEG4|ZN629_HUMAN 1 1153.6165 1.11 14088 17931 2 1153.620358 577.8155 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.47 3509.9 - 252574 - - - 3.3183 - 1.356 0.166 - 119.5 3 2 0 0.0038 10 0 0 0 6.71E+06 6.07E+06 - - - 0.9028 0.994 230117_WJC_METTL3_WT_vs_EV_F02.17934.17934.2 0.0312 14-Aug R.NILIVLTK.L "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN,tr|H0Y815|H0Y815_HUMAN" 3 912.6008 0.87 14089 17934 2 912.602196 457.3077 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 8.75 3510.3 - 412402 - - - 1.5253 - 1.53 0.088 - 196.4 2 2 0 0.0014 8 0 0 0 9.19E+06 1.06E+07 - - - 0.8386 1 230117_WJC_METTL3_WT_vs_EV_F02.17935.17935.2 1.62E-06 18-Nov R.EC[160.03]LNLWGYER.V sp|Q86U44|MTA70_HUMAN 1 1338.6027 23.77 14090 17935 2 1338.605315 670.3086 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3510.4 - 571047 - - - 1.9752 - 2.055 0.522 - 628.1 1 2 0 0.0026 10 0 0 0 6.51E+07 2.74E+06 - - - 4.9062 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.17938.17938.2 0.0359 14-Sep R.LSVLLGLK.K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 841.5637 2.38 14093 17938 2 841.565497 421.7891 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3510.8 - 218468 - - - 2.1472 - 2.07 0.33 - 217.9 1 2 0 0.0018 8 0 0 0 8.12E+06 3.42E+06 - - - 3.6721 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.17944.17944.2 0.000304 20-Oct R.YGLIGLNGIGK.S "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1103.6339 2.69 14097 17944 2 1103.637229 552.8242 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.59 3511.5 - 3.75E+06 - - - 3.0209 - 2.039 0.33 - 231 1 2 0 0.0033 11 0 0 0 5.92E+07 2.20E+07 - - - 3.4047 1 230117_WJC_METTL3_WT_vs_EV_F02.17946.17946.2 0.000328 18-Sep R.FLLADNLYC[160.03]K.A sp|P61758|PFD3_HUMAN 1 1255.6271 3.68 14099 17946 2 1255.629829 628.8208 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 5.83 3511.7 - 1.58E+06 - - - 2.1774 - 2.048 0.482 - 200.4 1 2 0 0.0027 10 0 0 0 4.37E+07 1.19E+07 - - - 4.6012 0.9556 230117_WJC_METTL3_WT_vs_EV_F02.17947.17947.2 0.0226 18-Aug G.AGALQVVGLK[136.11].T sp|Q9P1Q0|VPS54_HUMAN 1 962.6004 1.97 14100 17947 2 962.601713 482.3075 Vacuolar protein sorting-associated protein 54 OS=Homo sapiens OX=9606 GN=VPS54 PE=1 SV=2 8.8 3511.7 - 1.46E+06 - - - 1.3474 - 1.589 0.362 - 140 1 1 0 0.0013 10 0 0 0 1.53E+08 7.76E+07 - - - 3.007 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.17948.17948.2 0.0104 20-Jul K.LPVVISQC[160.03]GEM.- "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1231.5941 - 14101 17948 2 1231.595387 616.8043 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4 3511.8 - 855884 - - - 1.0612 - 1.137 0.295 - 99.1 1 2 0 0.0013 11 0 0 0 - - - - - 1.5668 1 230117_WJC_METTL3_WT_vs_EV_F02.17949.17949.2 1.37E-05 16-Sep K.NFDMVIVYK.D sp|Q9Y5B9|SP16H_HUMAN 1 1127.5685 1.09 14102 17949 2 1127.571966 564.7915 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.83 3511.9 - 719990 - - - 3.0588 - 1.821 0.549 - 231.5 1 2 0 0.0034 9 0 0 0 7.59E+06 6.97E+06 - - - 4.8289 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.17951.17951.2 0.000448 14-Aug R.LSVLLGLK[136.11].K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 849.5779 2.38 14104 17951 2 849.579685 425.7962 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3512.2 - 311418 - - - 2.1128 - 1.747 0.17 - 130.8 1 2 0 0.0018 8 0 0 0 7.91E+06 3.32E+06 - - - 1.9787 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.17955.17955.2 0.381 14-Jun R.VLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 815.4753 0.13 14108 17955 2 815.476438 408.7449 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 3512.7 - 231042 - - - 1.4335 - 1.306 0.269 - 88.6 1 2 0 0.0012 8 0 0 0 4.17E+06 3.32E+07 - - - 1.8326 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17958.17958.2 0.0062 20-Sep R.IVLLDSSLEYK[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1286.7213 10.54 14110 17958 2 1286.72351 644.3679 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3513 - 297828 - - - 1.7028 - 1.945 0.323 - 246.1 1 2 0 0.0022 11 0 0 0 1.91E+09 1.81E+08 - - - 3.2257 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.17964.17964.2 0.00186 18-Jul R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 23.77 14116 17964 2 1348.609643 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3513.6 - 252543 - - - -0.9625 - 1.555 0.415 - 180.4 1 2 0 -0.0013 10 0 0 0 6.51E+07 2.74E+06 - - - 3.3381 1 230117_WJC_METTL3_WT_vs_EV_F02.17968.17968.2 8.40E-05 18-Oct K.VEDAMLMFDK.T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|A0A6Q8PHP1|A0A6Q8PHP1_HUMAN" 6 1197.541 4.73 14118 17968 2 1197.546399 599.7778 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.03 3514.1 - 1.31E+06 - - - 4.5234 - 2.24 0.478 - 330.3 1 2 0 0.0054 10 0 0 0 2.79E+07 5.89E+06 - - - 4.8209 0.9919 230117_WJC_METTL3_WT_vs_EV_F02.17969.17969.2 0.071 14-Jul R.ADLIAYLK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 905.5222 1.57 14119 17969 2 905.525402 453.7684 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 5.88 3514.2 - 622970 - - - 3.5151 - 1.404 0.17 - 106.7 1 2 0 0.0032 8 0 0 0 2.39E+07 1.52E+07 - - - 1.319 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.17972.17972.2 0.00111 28-Nov R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 5.01 14122 17972 2 1484.906147 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3514.6 - 334506 - - - -1.1704 - 2.074 0.458 - 278.9 1 2 0 -0.0017 15 0 0 0 1.43E+07 2.86E+06 - - - 4.2167 0.9955 230117_WJC_METTL3_WT_vs_EV_F02.17973.17973.2 0.000173 20-Nov K.LALDMEINAYR.K sp|Q03252|LMNB2_HUMAN 1 1307.6544 0.97 14123 17973 2 1307.662183 654.8345 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.37 3514.8 - 259872 - - - 5.9733 - 2.427 0.335 - 515.5 1 2 0 0.0078 11 0 0 0 2.09E+06 2.16E+06 - - - 3.9115 1 230117_WJC_METTL3_WT_vs_EV_F02.17974.17974.2 1.93E-10 30-Oct K.VLAQNSGFDLQETLVK.L sp|P40227|TCPZ_HUMAN 1 1760.9309 1.86 14124 17974 2 1760.934784 881.4727 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3514.9 - 187685 - - - 2.2255 - 2.586 0.624 - 226.7 1 2 0 0.0039 16 0 0 0 2.25E+06 1.21E+06 - - - 5.9845 0.9956 230117_WJC_METTL3_WT_vs_EV_F02.17976.17976.2 0.0769 28-Jun R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 5.26 14126 17976 2 1494.92168 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3515.1 - 101487 - - - 3.6959 - 1.62 0.264 - 60.2 3 2 0 0.0055 15 0 0 0 1.58E+07 3.01E+06 - - - 1.9621 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.17982.17982.2 3.03E-05 20-Aug R.AVVPSYIPLVK.K sp|P36551|HEM6_HUMAN 1 1184.7169 1.11 14130 17982 2 1184.720544 593.3657 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3515.8 - 1.60E+06 - - - 3.0792 - 1.649 0.363 - 235 1 2 0 0.0036 11 0 0 0 1.86E+08 1.67E+08 - - - 3.074 1 230117_WJC_METTL3_WT_vs_EV_F02.17983.17983.2 3.05E-05 13/24 K.VLATTFDPYLGGR.N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1408.7351 12.84 14131 17983 2 1408.739278 705.3748 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3515.9 - 1.33E+06 - - - 2.9906 - 2.596 0.562 - 387.7 1 2 0 0.0042 13 0 0 0 5.33E+07 4.15E+06 - - - 5.639 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.17985.17985.2 0.0025 16-Jul R.FLSPEFIPR[166.11].R "sp|P49406|RM19_HUMAN,tr|A0A0A0MRF4|A0A0A0MRF4_HUMAN" 2 1114.6051 0.55 14133 17985 2 1114.608868 558.3098 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 6 3516.1 - 1.00E+06 - - - 3.4245 - 1.494 0.374 - 140.7 1 2 0 0.0038 9 0 0 0 1.75E+07 3.19E+07 - - - 2.9636 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.17988.17988.2 0.0444 18-Oct K.EVLLVALGSR.Q sp|Q10570|CPSF1_HUMAN 1 1055.6339 1.43 14136 17988 2 1055.636119 528.8242 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6.1 3516.5 - 412805 - - - 2.1068 - 2.24 0.313 - 309.4 1 2 0 0.0022 10 0 0 0 2.10E+07 1.47E+07 - - - 3.6032 0.9908 230117_WJC_METTL3_WT_vs_EV_F02.17992.17992.2 0.0249 24-Sep R.LPLLPPESPGPLR.Q "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN,tr|A0A669KAX5|A0A669KAX5_HUMAN" 6 1384.8078 3.39 14140 17992 2 1384.816571 693.4112 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 6 3517 - 143854 - - - 6.3077 - 1.968 0.315 - 226.4 1 2 0 0.0087 13 0 0 0 2.07E+06 6.13E+05 - - - 3.1024 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.17994.17994.2 0.00853 14-Aug K.NILTEIYR.L sp|Q15907|RB11B_HUMAN 1 1020.5604 1.83 14141 17994 2 1020.564177 511.2875 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 6 3517.2 - 651111 - - - 3.7058 - 1.665 0.338 - 241.1 1 2 0 0.0038 8 0 0 0 3.91E+07 2.14E+07 - - - 3.0739 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.17996.17996.2 0.026 14-Sep R.LDTIFFAK.Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 953.5222 2.44 14142 17996 2 953.525029 477.7684 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3517.4 - 1.89E+07 - - - 2.947 - 1.709 0.299 - 250.5 1 2 0 0.0028 8 0 0 0 1.49E+08 6.10E+07 - - - 2.8648 0.998 230117_WJC_METTL3_WT_vs_EV_F02.17997.17997.2 0.0708 16-Aug R.FLSPEFIPR.R "sp|P49406|RM19_HUMAN,tr|A0A0A0MRF4|A0A0A0MRF4_HUMAN" 2 1104.5968 0.52 14143 17997 2 1104.598668 553.3057 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 6 3517.5 - 3.00E+06 - - - 1.7083 - 1.41 0.23 - 136.6 1 2 0 0.0019 9 0 0 0 1.58E+07 3.05E+07 - - - 1.7332 0.9927 230117_WJC_METTL3_WT_vs_EV_F02.17999.17999.2 0.0401 14-Sep K.NILTEIYR[166.11].L sp|Q15907|RB11B_HUMAN 1 1030.5687 1.84 14145 17999 2 1030.573982 516.2916 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 6 3517.7 - 1.46E+06 - - - 5.1593 - 1.716 0.242 - 305.3 1 2 0 0.0053 8 0 0 0 3.91E+07 2.12E+07 - - - 2.4553 0.9947 230117_WJC_METTL3_WT_vs_EV_F02.18000.18000.2 0.746 14-Aug K.ILILQGLK.Q "sp|Q9UNX4|WDR3_HUMAN,tr|D6RCT0|D6RCT0_HUMAN" 2 896.6059 1.09 14146 18000 2 896.609001 449.3102 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 8.75 3517.8 - 1.40E+06 - - - 3.4709 - 1.64 0.151 - 171.4 1 2 0 0.0031 8 0 0 0 1.97E+07 1.80E+07 - - - 1.6473 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.18001.18001.2 0.209 14-Aug R.ADLIAYLK[136.11].K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 913.5364 1.57 14147 18001 2 913.539772 457.7755 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 5.88 3517.9 - 1.12E+06 - - - 3.6704 - 1.699 0.183 - 161.6 1 2 0 0.0034 8 0 0 0 2.39E+07 1.52E+07 - - - 1.9902 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.18002.18002.2 0.697 18-Oct K.VLALLDVPDK.S sp|Q9NX62|IMPA3_HUMAN 1 1081.6383 0.91 14148 18002 2 1081.642742 541.8264 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.21 3518.1 - 698699 - - - 4.0966 - 2.045 0.17 - 288.4 1 2 0 0.0044 10 0 0 0 4.93E+07 5.42E+07 - - - 2.2921 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.18003.18003.2 0.000211 24-Sep K.VLATTFDPYLGGR[166.11].N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1418.7433 12.67 14149 18003 2 1418.749453 710.3789 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3518.2 - 341279 - - - 4.3123 - 2.052 0.457 - 179.7 1 2 0 0.0061 13 0 0 0 5.26E+07 4.15E+06 - - - 4.2593 0.9952 230117_WJC_METTL3_WT_vs_EV_F02.18009.18009.2 0.367 14-Aug R.GIFEPFGR.L "sp|Q14498|RBM39_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 5 921.4709 1.01 14153 18009 2 921.473618 461.7427 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 6 3518.9 - 1.01E+06 - - - 3.0017 - 1.559 0.15 - 172 1 2 0 0.0028 8 0 0 0 7.91E+07 7.79E+07 - - - 1.4872 0.9871 230117_WJC_METTL3_WT_vs_EV_F02.18012.18012.2 0.0145 18-Nov K.VLALLDVPDK[136.11].S sp|Q9NX62|IMPA3_HUMAN 1 1089.6525 0.91 14156 18012 2 1089.659286 545.8335 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.21 3519.3 - 940734 - - - 6.2176 - 2.105 0.202 - 341.9 1 2 0 0.0068 10 0 0 0 4.94E+07 5.42E+07 - - - 2.6085 0.9969 230117_WJC_METTL3_WT_vs_EV_F02.18013.18013.2 0.00472 20-Sep R.LLALNSLYSPK.L sp|P78527|PRKDC_HUMAN 1 1217.702 1.33 14157 18013 2 1217.707911 609.8583 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.59 3519.4 - 888096 - - - 4.8756 - 1.765 0.364 - 179.2 1 2 0 0.0059 11 0 0 0 8.81E+07 6.62E+07 - - - 3.2646 0.9963 230117_WJC_METTL3_WT_vs_EV_F02.18016.18016.2 0.00261 18-Oct R.LITTQQWLIK[136.11].L sp|P00846|ATP6_HUMAN 1 1250.7478 1.1 14160 18016 2 1250.753413 626.3812 ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1 8.75 3519.8 - 376490 - - - 4.4805 - 1.897 0.253 - 239.8 1 2 0 0.0056 10 0 0 0 8.23E+06 7.49E+06 - - - 2.6951 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.18018.18018.2 0.000561 18-Oct R.LITTQQWLIK.L sp|P00846|ATP6_HUMAN 1 1242.7336 1.1 14162 18018 2 1242.740345 622.3741 ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1 8.75 3520 - 309443 - - - 5.4203 - 1.922 0.469 - 202.1 1 2 0 0.0067 10 0 0 0 8.23E+06 7.49E+06 - - - 4.3267 1 230117_WJC_METTL3_WT_vs_EV_F02.18027.18027.2 1.15E-10 13/38 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 9.74 14171 18027 2 2187.052975 1094.5262 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3521.2 - 40842.3 - - - 6.9084 - 2.96 0.564 - 406.2 1 2 0 0.0151 20 0 0 0 6.34E+06 6.51E+05 - - - 5.8699 0.9957 230117_WJC_METTL3_WT_vs_EV_F02.18029.18029.2 0.0061 16-Sep R.AVALYFIDK[136.11].L "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN,tr|E5RIC7|E5RIC7_HUMAN" 4 1046.5892 1.29 14172 18029 2 1046.595441 524.3019 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 5.88 3521.5 - 1.05E+06 - - - 5.9794 - 1.817 0.436 - 285.8 1 2 0 0.0063 9 0 0 0 4.17E+07 3.23E+07 - - - 3.987 1 230117_WJC_METTL3_WT_vs_EV_F02.18031.18031.2 5.37E-06 15/18 R.IC[160.03]DDELILIK.N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1230.653 9.85 14173 18031 2 1230.65614 616.3338 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3521.7 - 1.41E+07 - - - 2.571 - 2.844 0.426 - 586.4 1 2 0 0.0032 10 0 0 0 1.30E+09 1.32E+08 - - - 5.1039 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18032.18032.2 0.00395 14-Sep R.LDTIFFAK[136.11].Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 961.5364 2.48 14174 18032 2 961.538627 481.7755 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3521.8 - 3.13E+06 - - - 2.2963 - 1.867 0.301 - 242.3 1 2 0 0.0022 8 0 0 0 1.44E+08 5.82E+07 - - - 3.1465 1 230117_WJC_METTL3_WT_vs_EV_F02.18034.18034.2 5.23E-05 13/18 R.IC[160.03]DDELILIK[136.11].N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1238.6672 9.86 14176 18034 2 1238.671107 620.3409 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3522 - 1.95E+06 - - - 3.1736 - 2.839 0.416 - 366.9 1 2 0 0.0039 10 0 0 0 1.30E+09 1.32E+08 - - - 5.0249 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.18035.18035.2 0.00149 16-Oct K.IIGNLLYYR[166.11].Y "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1133.6472 1.22 14177 18035 2 1133.652317 567.8309 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.59 3522.1 - 1.13E+06 - - - 4.4696 - 2.011 0.287 - 211.1 1 2 0 0.0051 9 0 0 0 5.28E+07 4.34E+07 - - - 3.1804 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.18036.18036.2 0.0193 16-Aug K.IIGNLLYYR.Y "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1123.639 1.22 14178 18036 2 1123.644213 562.8268 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.59 3522.2 - 1.01E+06 - - - 4.6572 - 1.8 0.268 - 117.3 1 2 0 0.0052 9 0 0 0 5.28E+07 4.34E+07 - - - 2.7193 1 230117_WJC_METTL3_WT_vs_EV_F02.18039.18039.3 6.20E-11 17/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 5.1 14181 18039 3 2187.051518 730.0199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3522.6 - 315802 - - - 6.2422 - 3.233 0.597 - 271.7 1 2 0 0.0137 20 0 0 0 1.08E+07 2.12E+06 - - - 8.0389 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18046.18046.3 0.0639 13/36 R.FSVLLLHGIR.F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1153.6972 2.56 14186 18046 3 1153.700131 385.573 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3523.5 - 1.29E+06 - - - 2.5717 - 2.164 0.33 - 206.1 1 2 0 0.003 10 0 0 0 1.55E+07 6.07E+06 - - - 4.4728 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.18048.18048.2 0.000102 20-Sep K.VLTPELYAELR[166.11].A "sp|P12277|KCRB_HUMAN,tr|G3V461|G3V461_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 3 1312.7266 0.84 14188 18048 2 1312.724132 657.3706 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.53 3523.7 - 694752 - - - -1.8976 - 2.021 0.389 - 218.5 1 2 0 -0.0025 11 0 0 0 7.16E+07 8.52E+07 - - - 3.8168 0.8573 230117_WJC_METTL3_WT_vs_EV_F02.18049.18049.2 2.19 14-Jun R.LYPVLLVK.Q "sp|Q7Z7F7|RM55_HUMAN,tr|X6RIW1|X6RIW1_HUMAN" 2 943.6106 1.09 14189 18049 2 943.614861 472.8126 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 8.59 3523.8 - 614320 - - - 4.4732 - 0.973 0.097 - 77.5 1 2 0 0.0042 8 0 0 0 2.62E+07 2.41E+07 - - - -0.3264 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.18050.18050.3 0.556 Dec-36 R.FSVLLLHGIR[166.11].F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1163.7054 2.51 14190 18050 3 1163.708347 388.9091 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3523.9 - 586290 - - - 2.5032 - 2.168 0.214 - 109.7 1 2 0 0.0029 10 0 0 0 1.55E+07 6.18E+06 - - - 3.1849 0.9735 230117_WJC_METTL3_WT_vs_EV_F02.18051.18051.2 0.454 14-Jun K.NLEIELLK.L "sp|Q9NVX0|HAUS2_HUMAN,tr|H3BP24|H3BP24_HUMAN,tr|J3QT48|J3QT48_HUMAN,tr|H3BQU2|H3BQU2_HUMAN,tr|H3BP16|H3BP16_HUMAN" 5 970.5699 2.93 14191 18051 2 970.572424 486.2922 HAUS augmin-like complex subunit 2 OS=Homo sapiens OX=9606 GN=HAUS2 PE=1 SV=1 4.53 3524.1 - 334026 - - - 2.6026 - 1.287 0.064 - 81.4 3 2 0 0.0025 8 0 0 0 5.05E+06 1.72E+06 - - - 0.0607 0.8871 230117_WJC_METTL3_WT_vs_EV_F02.18058.18058.2 0.00514 16-Aug K.TVTAMDVVY.A sp|P62805|H4_HUMAN 1 997.479 - 14196 18058 2 997.482166 499.7468 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 3.8 3525 - 1.66E+06 - - - 3.1399 - 1.301 0.383 - 154.5 1 1 0 0.0031 9 0 0 0 - - - - - 2.6301 0.995 230117_WJC_METTL3_WT_vs_EV_F02.18059.18059.2 0.106 14-Aug K.IDHILDAL.- "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 908.4967 - 14197 18059 2 908.499657 455.2556 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.2 3525.1 - 746272 - - - 3.2185 - 1.558 0.16 - 181.1 1 2 0 0.0029 8 0 0 0 - - - - - 1.5591 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.18060.18060.2 0.0552 14-Jul R.DVDFELIK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 985.5212 5.07 14198 18060 2 985.522447 493.7679 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3525.1 - 1.13E+06 - - - 1.3029 - 1.101 0.267 - 120.1 1 2 0 0.0013 8 0 0 0 8.84E+08 1.74E+08 - - - 1.3029 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.18063.18063.2 0.0377 16-Aug R.SSIAGLLLK.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 900.5644 8.14 14201 18063 2 900.565282 451.2895 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.47 3525.4 - 480961 - - - 0.9594 - 1.629 0.254 - 139.6 1 2 0 0.0009 9 0 0 0 4.15E+07 5.10E+06 - - - 2.3285 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18065.18065.2 0.000354 22-Sep R.IGPLSPFTNAYR[166.11].R "sp|O75486|SUPT3_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 2 1344.7066 1.7 14203 18065 2 1344.707989 673.3606 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 8.75 3525.7 - 383192 - - - 1.0657 - 2.023 0.408 - 149.8 1 2 0 0.0014 12 0 0 0 2.05E+07 1.21E+07 - - - 3.9079 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18074.18074.2 0.00129 18-Aug R.VVYIFGPPVK.E sp|P49915|GUAA_HUMAN 1 1117.6536 5.64 14210 18074 2 1117.655001 559.8341 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 8.56 3526.6 - 982149 - - - 1.2822 - 1.683 0.42 - 248.4 1 2 0 0.0014 10 0 0 0 2.09E+07 3.71E+06 - - - 3.5958 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18082.18082.2 0.00867 14-Oct R.LFGALLER[166.11].G sp|Q9BVI4|NOC4L_HUMAN 1 927.5417 1.15 14216 18082 2 927.542432 464.7781 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3527.6 - 4.90E+06 - - - 0.7655 - 2.215 0.203 - 345.8 1 2 0 0.0007 8 0 0 0 1.38E+08 1.20E+08 - - - 2.9386 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.18084.18084.2 0.0172 16-Sep R.VILLENLTR.F "sp|Q14999|CUL7_HUMAN,tr|A0A669KB95|A0A669KB95_HUMAN,tr|A0A669KAU7|A0A669KAU7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 4 1069.6495 1.51 14218 18084 2 1069.654026 535.832 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 5.97 3527.8 - 1.41E+06 - - - 4.1892 - 1.808 0.314 - 212.6 1 2 0 0.0045 9 0 0 0 2.24E+07 1.48E+07 - - - 3.0721 0.9874 230117_WJC_METTL3_WT_vs_EV_F02.18086.18086.2 1 12-Jun K.FLELLPK.D "sp|P63010|AP2B1_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 5 858.5215 1.61 14220 18086 2 858.523069 430.268 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 6 3528.1 - 540861 - - - 1.838 - 1.172 0.128 - 111 2 2 0 0.0016 7 0 0 0 3.20E+07 1.99E+07 - - - 0.3543 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.18088.18088.2 4.53E-06 22-Dec R.LLQTIAVLEAQR.S sp|Q8IYH5|ZZZ3_HUMAN 1 1353.798 4.42 14222 18088 2 1353.803545 677.9063 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 6 3528.3 - 389899 - - - 4.0959 - 2.148 0.332 - 615.8 1 2 0 0.0055 12 0 0 0 7.14E+06 1.62E+06 - - - 3.503 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.18090.18090.2 0.00103 20-Oct R.LLMLGLDNAGK.T "sp|P36404|ARL2_HUMAN,tr|V9GYD0|V9GYD0_HUMAN" 2 1143.6322 2.82 14224 18090 2 1143.636505 572.8234 ADP-ribosylation factor-like protein 2 OS=Homo sapiens OX=9606 GN=ARL2 PE=1 SV=4 5.84 3528.6 - 291652 - - - 3.7818 - 1.777 0.369 - 203.5 1 2 0 0.0043 11 0 0 0 5.59E+06 1.98E+06 - - - 3.3204 0.9297 230117_WJC_METTL3_WT_vs_EV_F02.18091.18091.2 2.29 18-Aug R.FSVLLLHGIR[166.11].F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1163.7054 6.5 14225 18091 2 1163.709158 582.86 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3528.7 - 250014 - - - 3.2001 - 1.127 0.035 - 85.5 1 2 0 0.0037 10 0 0 0 7.69E+06 1.18E+06 - - - -0.3679 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18095.18095.2 0.0148 14-Oct R.LFGALLER.G sp|Q9BVI4|NOC4L_HUMAN 1 917.5335 0.98 14227 18095 2 917.534697 459.774 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3529.2 - 5.59E+06 - - - 1.3569 - 2.051 0.213 - 301.8 1 2 0 0.0012 8 0 0 0 1.12E+08 1.15E+08 - - - 2.7803 0.9814 230117_WJC_METTL3_WT_vs_EV_F02.18098.18098.2 1.18 14-Jun R.LYPVLLVK[136.11].Q "sp|Q7Z7F7|RM55_HUMAN,tr|X6RIW1|X6RIW1_HUMAN" 2 951.6248 1.09 14230 18098 2 951.627624 476.8197 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 8.59 3529.5 - 659720 - - - 2.9255 - 1.014 0.182 - 75.3 1 2 0 0.0028 8 0 0 0 2.62E+07 2.41E+07 - - - 0.4263 1 230117_WJC_METTL3_WT_vs_EV_F02.18101.18101.2 0.000108 22-Dec K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 23.39 14233 18101 2 1474.74447 738.3781 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3529.9 - 379195 - - - 1.9414 - 2.72 0.547 - 585 1 2 0 0.0029 12 0 0 0 9.01E+06 3.85E+05 - - - 5.7131 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.18106.18106.2 0.0854 16-Jul R.VVLPYLVPK.L sp|Q92616|GCN1_HUMAN 1 1026.6478 1.14 14236 18106 2 1026.649621 514.3312 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.56 3530.6 - 1.49E+06 - - - 1.8185 - 1.337 0.288 - 133.1 1 2 0 0.0019 9 0 0 0 4.65E+07 4.08E+07 - - - 2.0078 0.9964 230117_WJC_METTL3_WT_vs_EV_F02.18107.18107.2 19.3 12-Aug R.LLDFLQK.R "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 875.5117 1.33 14237 18107 2 875.512269 438.7631 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.84 3530.7 - 5.95E+06 - - - 0.7024 - 1.523 0.124 - 158.5 1 2 0 0.0006 7 0 0 0 8.93E+07 6.73E+07 - - - 1.2896 1 230117_WJC_METTL3_WT_vs_EV_F02.18111.18111.2 2.37E-05 16-Oct R.LSMMLLDSR[166.11].A "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1074.5441 3.94 14241 18111 2 1074.546601 538.2793 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.84 3530.9 - 1.95E+06 - - - 2.321 - 2.056 0.479 - 314.4 1 2 0 0.0025 9 0 0 0 8.11E+07 2.06E+07 - - - 4.6633 0.9783 230117_WJC_METTL3_WT_vs_EV_F02.18113.18113.2 1.26 14-Jul K.IISLDAWR.V "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 972.5393 1.92 14243 18113 2 972.541501 487.2769 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.84 3531.1 - 607001 - - - 2.2981 - 1.481 0.011 - 84.9 3 2 0 0.0022 8 0 0 0 3.05E+07 1.59E+07 - - - 0.0928 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18119.18119.2 0.000436 16-Nov K.LYSLSVLYK.G "sp|O15498|YKT6_HUMAN,tr|A0A7I2V530|A0A7I2V530_HUMAN,tr|A0A7I2V3S2|A0A7I2V3S2_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 6 1084.6168 5.95 14247 18119 2 1084.61832 543.3157 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 8.5 3531.9 - 516743 - - - 1.3572 - 2.143 0.43 - 292.8 1 2 0 0.0015 9 0 0 0 2.00E+07 3.37E+06 - - - 4.4216 1 230117_WJC_METTL3_WT_vs_EV_F02.18123.18123.2 1.09E-05 20-Oct R.FPC[160.03]VVYINEVR.V sp|Q69YN4|VIR_HUMAN 1 1394.7017 2.29 14251 18123 2 1394.702393 698.3581 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 5.99 3532.4 - 136042 - - - 0.5277 - 2.123 0.51 - 464.6 1 2 0 0.0007 11 0 0 0 4.70E+06 2.06E+06 - - - 4.8442 1 230117_WJC_METTL3_WT_vs_EV_F02.18134.18134.2 9.16E-07 13/22 K.LFVTNDAATILR[166.11].E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1342.7484 8.01 14257 18134 2 1342.752362 672.3815 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3533.7 - 3.27E+06 - - - 2.935 - 2.586 0.485 - 541.5 1 2 0 0.0039 12 0 0 0 5.89E+09 7.35E+08 - - - 5.1219 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18135.18135.2 0.00176 14-Sep K.LDYILGLK[136.11].L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 941.5677 0.77 14258 18135 2 941.569152 471.7911 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3533.8 - 2.66E+06 - - - 1.5219 - 1.921 0.297 - 267.2 1 2 0 0.0014 8 0 0 0 4.06E+08 5.25E+08 - - - 3.2031 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18139.18139.2 0.0137 20-Oct K.AVFVLGDAELK[136.11].G "sp|Q93074|MED12_HUMAN,tr|Q7Z3Z5|Q7Z3Z5_HUMAN" 2 1168.6583 0.26 14262 18139 2 1168.659375 585.3364 Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens OX=9606 GN=MED12 PE=1 SV=4 4.37 3534.3 - 259664 - - - 0.8985 - 1.646 0.354 - 201.9 1 2 0 0.001 11 0 0 0 6.57E+06 2.56E+07 - - - 3.0035 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18142.18142.2 0.0168 14-Sep K.LDYILGLK.L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 933.5535 0.79 14263 18142 2 933.555612 467.784 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3534.6 - 863685 - - - 2.242 - 1.892 0.304 - 264.3 1 2 0 0.0021 8 0 0 0 4.06E+08 5.15E+08 - - - 3.2088 0.9911 230117_WJC_METTL3_WT_vs_EV_F02.18145.18145.2 0.0993 14-Jul R.QMFLATWK.D sp|Q10567|AP1B1_HUMAN 1 1023.5212 0.53 14266 18145 2 1023.522471 512.7679 AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2 8.75 3534.9 - 322802 - - - 1.2682 - 1.154 0.146 - 116.1 1 2 0 0.0013 8 0 0 0 5.46E+06 1.04E+07 - - - 0.5509 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.18146.18146.2 2.18 14-Jul R.LLILMEAR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 967.5764 1.48 14267 18146 2 967.576941 484.7955 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6 3535 - 304697 - - - 0.5664 - 1.611 0.254 - 170.6 1 2 0 0.0005 8 0 0 0 4.18E+07 2.82E+07 - - - 2.355 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18152.18152.2 0.00362 14-Oct R.VVDLLVIK.G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 897.5899 2.14 14271 18152 2 897.590443 449.8022 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3535.8 - 2.48E+06 - - - 0.5994 - 1.71 0.434 - 275.3 1 2 0 0.0005 8 0 0 0 1.45E+08 6.78E+07 - - - 3.8644 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18155.18155.2 0.00135 18-Oct K.LAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1142.627 3.17 14274 18155 2 1142.629325 572.3208 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3536 - 812353 - - - 2.0042 - 2.039 0.304 - 387.6 1 2 0 0.0023 10 0 0 0 7.83E+08 2.47E+08 - - - 3.2743 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.18156.18156.2 2.5 14-Jul R.LLILMEAR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 957.5681 1.48 14275 18156 2 957.56877 479.7913 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6 3536.1 - 684499 - - - 0.6757 - 1.653 0.195 - 156.6 1 2 0 0.0006 8 0 0 0 4.18E+07 2.82E+07 - - - 1.9969 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.18157.18157.2 0.0535 16-Oct K.LFLVQLQEK[136.11].A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1124.6685 1.18 14276 18157 2 1124.672539 563.3415 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3536.2 - 596866 - - - 3.5948 - 1.884 0.335 - 292.1 1 2 0 0.004 9 0 0 0 4.26E+07 3.60E+07 - - - 3.3465 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.18161.18161.2 0.00475 18-Aug K.YLAIAPPIIK.Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1097.6849 1.9 14278 18161 2 1097.685278 549.8497 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3536.6 - 3.16E+06 - - - 0.3735 - 1.507 0.305 - 220.8 1 2 0 0.0004 10 0 0 0 1.82E+08 9.54E+07 - - - 2.4384 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.18162.18162.3 6.85E-05 15/44 K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 7.98 14279 18162 3 1332.741032 445.254 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3536.7 - 7.76E+06 - - - 0.661 - 2.403 0.449 - 340.8 1 2 0 0.0009 12 0 0 0 1.06E+08 1.33E+07 - - - 5.9758 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.18163.18163.2 0.103 16-Jun K.VLEALQVLR[166.11].C "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1049.6472 1.36 14280 18163 2 1049.647857 525.8309 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.97 3536.8 - 2.61E+06 - - - 0.5783 - 1.704 0.222 - 90.5 13 2 0 0.0006 9 0 0 0 6.00E+07 4.40E+07 - - - 1.7248 0.9804 230117_WJC_METTL3_WT_vs_EV_F02.18166.18166.2 1.97 12-Jun K.FLELLPK[136.11].D "sp|P63010|AP2B1_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 5 866.5357 1.62 14283 18166 2 866.535473 434.2751 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 6 3537.1 - 1.11E+06 - - - -0.2516 - 0.99 0.184 - 68.9 1 2 0 -0.0002 7 0 0 0 3.20E+07 1.98E+07 - - - 0.3681 0.9938 230117_WJC_METTL3_WT_vs_EV_F02.18167.18167.2 0.000347 20-Oct K.YGLLPSHASYL.- sp|Q86U90|YRDC_HUMAN 1 1219.6237 - 14284 18167 2 1219.621804 610.8191 "YrdC domain-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=YRDC PE=1 SV=1" 6.74 3537.3 - 755793 - - - -1.5743 - 1.676 0.202 - 184.5 1 2 0 -0.0019 11 0 0 0 - - - - - 1.9294 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18172.18172.2 0.0323 16-Sep R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 1380.15 14288 18172 2 1006.570854 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3537.9 - 1.07E+07 - - - 0.9498 - 1.637 0.348 - 199.4 1 2 0 0.001 9 0 0 0 1.24E+08 9.02E+04 - - - 3.0369 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18174.18174.2 0.00373 16-Oct K.VLEALQVLR.C "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1039.639 1.36 14289 18174 2 1039.638543 520.8268 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.97 3538.1 - 740210 - - - -0.4203 - 2.121 0.423 - 381.4 1 2 0 -0.0004 9 0 0 0 6.00E+07 4.40E+07 - - - 4.3404 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18176.18176.2 0.0135 16-Aug K.LFLVQLQEK.A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1116.6543 1.14 14291 18176 2 1116.655547 559.3344 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3538.2 - 690045 - - - 1.1203 - 1.783 0.386 - 214.6 1 2 0 0.0013 9 0 0 0 4.08E+07 3.58E+07 - - - 3.5646 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18188.18188.2 0.016 18-Aug K.YLAIAPPIIK[136.11].Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1105.6991 1.9 14301 18188 2 1105.700111 553.8568 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3539.6 - 1.14E+07 - - - 0.9433 - 1.6 0.359 - 196.8 1 2 0 0.001 10 0 0 0 1.81E+08 9.52E+07 - - - 3.0042 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18190.18190.2 0.00108 14-Sep R.VVDLLVIK[136.11].G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 905.6041 2.14 14303 18190 2 905.604191 453.8093 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3539.8 - 1.10E+07 - - - 0.095 - 1.774 0.443 - 198.7 1 2 0 0.0001 8 0 0 0 1.45E+08 6.78E+07 - - - 4.0418 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.18191.18191.2 0.00211 14-Sep R.YQDILVFR.S "sp|P19623|SPEE_HUMAN,tr|K7EKM4|K7EKM4_HUMAN" 2 1052.5655 5.59 14304 18191 2 1052.571904 527.29 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.84 3539.9 - 7.32E+06 - - - 6.1022 - 1.954 0.443 - 252.8 1 2 0 0.0064 8 0 0 0 7.13E+07 1.28E+07 - - - 4.3313 0.9877 230117_WJC_METTL3_WT_vs_EV_F02.18193.18193.2 3.17 12-Aug R.SLSDLFR.R "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 836.4392 1.12 14306 18193 2 836.43931 419.2269 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 5.55 3540.1 - 3.07E+06 - - - 0.11 - 1.554 0.016 - 221.5 1 2 0 0.0001 7 0 0 0 2.44E+07 2.18E+07 - - - 0.5559 1 230117_WJC_METTL3_WT_vs_EV_F02.18194.18194.2 1.34E-06 15/30 R.IINEPTAAAIAYGLDK.R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1658.8879 38.22 14307 18194 2 1658.88787 830.4512 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3540.2 - 3.06E+06 - - - -0.0404 - 2.722 0.529 - 381.5 1 2 0 -0.0001 16 0 0 0 3.19E+07 8.33E+05 - - - 5.4101 1 230117_WJC_METTL3_WT_vs_EV_F02.18195.18195.2 0.000156 20-Nov K.LIVAYVDDLDR.R "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1290.682 1.27 14308 18195 2 1290.68349 646.3483 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 3.93 3540.3 - 2.83E+06 - - - 1.18 - 2.257 0.484 - 512 1 2 0 0.0015 11 0 0 0 1.41E+07 1.11E+07 - - - 4.8175 1 230117_WJC_METTL3_WT_vs_EV_F02.18197.18197.2 4.54E-05 20-Nov K.LIVAYVDDLDR[166.11].R "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1300.6902 1.27 14310 18197 2 1300.692554 651.3524 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 3.93 3540.6 - 1.85E+06 - - - 1.7814 - 2.273 0.503 - 488.4 1 2 0 0.0023 11 0 0 0 1.41E+07 1.11E+07 - - - 4.9767 0.9253 230117_WJC_METTL3_WT_vs_EV_F02.18201.18201.2 0.305 16-Sep R.NFFGPEFVK.M sp|Q12923|PTN13_HUMAN 1 1083.5389 0.12 14314 18201 2 1083.535013 542.7767 Tyrosine-protein phosphatase non-receptor type 13 OS=Homo sapiens OX=9606 GN=PTPN13 PE=1 SV=2 6 3541.1 - 701099 - - - -3.6169 - 1.149 0.195 - 153.9 1 2 0 -0.0039 9 0 0 0 5.96E+06 5.04E+07 - - - 0.8819 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18204.18204.2 0.0283 18-Nov K.LAVNMVPFPR[166.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1152.6353 3.17 14316 18204 2 1152.635922 577.3249 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3541.5 - 1.54E+07 - - - 0.5353 - 2.027 0.286 - 531.2 1 2 0 0.0006 10 0 0 0 7.83E+08 2.47E+08 - - - 3.1254 0.9851 230117_WJC_METTL3_WT_vs_EV_F02.18206.18206.2 0.494 12-Jul R.ALLFIPR.R "sp|P08238|HS90B_HUMAN,sp|O00585|CCL21_HUMAN,tr|Q5VZ73|Q5VZ73_HUMAN" 3 828.5222 2.11 14317 18206 2 828.522184 415.2684 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 9.79 3541.7 - 3.27E+06 - - - 0.0302 - 1.373 0.073 - 212 2 2 0 0 7 0 0 0 4.43E+08 2.09E+08 - - - 0.4501 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.18209.18209.2 0.0193 16-Jun K.LLQDFFNGK.E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1080.5604 9.4 14320 18209 2 1080.56082 541.2875 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3541.9 - 5.10E+06 - - - 0.3933 - 1.267 0.291 - 78.1 1 2 0 0.0004 9 0 0 0 8.57E+07 9.11E+06 - - - 1.8748 0.9803 230117_WJC_METTL3_WT_vs_EV_F02.18210.18210.2 0.535 12-May R.GWLNIVR.H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 856.4919 1.82 14321 18210 2 856.491589 429.2532 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 9.75 3541.9 - 2.15E+06 - - - -0.3888 - 1.004 0.214 - 85.6 3 2 0 -0.0003 7 0 0 0 2.04E+07 1.12E+07 - - - 0.421 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.18214.18214.3 0.0758 Aug-36 K.LAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1142.627 3.11 14325 18214 3 1142.627424 381.883 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3542.3 - 464289 - - - 0.3404 - 1.677 0.221 - 105.4 1 2 0 0.0004 10 0 0 0 6.01E+06 1.93E+06 - - - 2.5137 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18218.18218.2 0.00183 18-Oct R.VLITTDLLAR.G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 1113.6758 1.52 14327 18218 2 1113.676788 557.8452 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3542.8 - 3.46E+06 - - - 0.9231 - 2.127 0.34 - 301.9 1 2 0 0.001 10 0 0 0 2.91E+08 1.91E+08 - - - 3.6585 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18219.18219.2 0.000129 18-Oct R.VLITTDLLAR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 1123.684 1.52 14328 18219 2 1123.685474 562.8493 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3542.9 - 2.95E+06 - - - 1.2851 - 2.109 0.464 - 252.3 1 2 0 0.0014 10 0 0 0 2.91E+08 1.91E+08 - - - 4.5506 0.9439 230117_WJC_METTL3_WT_vs_EV_F02.18220.18220.2 6.59 12-Jul R.ALLFIPR[166.11].R "sp|P08238|HS90B_HUMAN,sp|O00585|CCL21_HUMAN,tr|Q5VZ73|Q5VZ73_HUMAN" 3 838.5304 2.11 14329 18220 2 838.530861 420.2725 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 9.79 3543 - 1.96E+06 - - - 0.5152 - 1.157 0.018 - 249.8 3 2 0 0.0004 7 0 0 0 4.42E+08 2.09E+08 - - - -0.5772 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.18222.18222.2 0.0162 12-Jul R.AVFWDIK.N sp|Q6P2Q9|PRP8_HUMAN 1 877.4698 1.14 14331 18222 2 877.471073 439.7422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3543.2 - 839558 - - - 1.4622 - 1.245 0.299 - 203.6 1 2 0 0.0013 7 0 0 0 6.03E+07 5.27E+07 - - - 1.9434 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.18229.18229.2 0.833 14-Aug R.DVDFELIK.V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 977.507 3.33 14336 18229 2 977.508741 489.7608 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3544 - 2.36E+06 - - - 1.8189 - 1.523 0.234 - 171.3 1 2 0 0.0018 8 0 0 0 9.53E+08 2.86E+08 - - - 2.0375 1 230117_WJC_METTL3_WT_vs_EV_F02.18230.18230.2 3.53E-05 18-Sep K.FYALDPSFPR.M sp|Q08J23|NSUN2_HUMAN 1 1211.5975 1.71 14337 18230 2 1211.59757 606.806 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3544.1 - 601297 - - - 0.0503 - 1.783 0.535 - 268 1 2 0 0.0001 10 0 0 0 1.15E+07 6.75E+06 - - - 4.6067 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18235.18235.2 0.0641 22-Oct R.APVVAIAVLDGR[166.11].G "sp|Q15334|L2GL1_HUMAN,tr|A0A087WW77|A0A087WW77_HUMAN" 2 1189.7058 2.07 14342 18235 2 1189.704945 595.8602 Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens OX=9606 GN=LLGL1 PE=1 SV=3 5.88 3544.7 - 282045 - - - -0.7422 - 2.47 0.412 - 351.7 1 2 0 -0.0009 12 0 0 0 8.41E+06 4.07E+06 - - - 4.4629 1 230117_WJC_METTL3_WT_vs_EV_F02.18238.18238.2 0.00316 22-Dec K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 8.01 14344 18238 2 1332.741897 667.3774 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3545.1 - 1.57E+07 - - - 1.3101 - 2.446 0.532 - 565.3 1 2 0 0.0017 12 0 0 0 5.89E+09 7.35E+08 - - - 5.3233 0.9946 230117_WJC_METTL3_WT_vs_EV_F02.18240.18240.2 0.0463 16-Sep R.LIDFLEC[160.03]GK[136.11].T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1101.562 0.93 14345 18240 2 1101.558592 551.7883 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3545.3 - 8.45E+06 - - - -3.0774 - 1.721 0.342 - 215 1 2 0 -0.0034 9 0 0 0 1.31E+08 1.40E+08 - - - 3.1366 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.18241.18241.2 0.0135 12-May R.AVFWDIK[136.11].N sp|Q6P2Q9|PRP8_HUMAN 1 885.484 1.14 14346 18241 2 885.485057 443.7493 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3545.3 - 3.99E+06 - - - 1.205 - 1.381 0.297 - 101.8 1 2 0 0.0011 7 0 0 0 6.04E+07 5.28E+07 - - - 2.2571 0.999 230117_WJC_METTL3_WT_vs_EV_F02.18243.18243.2 5.53E-05 28-Aug R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 27.46 14348 18243 2 1484.90879 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3545.5 - 278918 - - - 0.6095 - 1.866 0.268 - 175.5 1 2 0 0.0009 15 0 0 0 8.05E+06 2.93E+05 - - - 2.5538 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18251.18251.2 5.87E-05 20-Dec K.LDPGLIMEQVK.V sp|Q9Y5L4|TIM13_HUMAN 1 1241.669 2.27 14354 18251 2 1241.672743 621.8418 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3546.5 - 1.79E+06 - - - 3.0467 - 2.179 0.432 - 527.1 1 2 0 0.0038 11 0 0 0 1.87E+07 8.26E+06 - - - 4.3376 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.18253.18253.2 0.000659 13/22 R.FLAVGLVDNTVR.L sp|Q15393|SF3B3_HUMAN 1 1302.7296 1.13 14356 18253 2 1302.736272 652.3721 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3546.7 - 1.62E+06 - - - 5.1323 - 2.119 0.367 - 510.2 1 2 0 0.0067 12 0 0 0 1.82E+08 1.61E+08 - - - 3.7254 0.8526 230117_WJC_METTL3_WT_vs_EV_F02.18254.18254.2 1.43 12-Aug Y.LFSLPIK.E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|Q5JVC1|Q5JVC1_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN,tr|H3BNG3|H3BNG3_HUMAN,tr|H0YE27|H0YE27_HUMAN,tr|Q5JVC2|Q5JVC2_HUMAN" 9 816.5109 0.84 14357 18254 2 816.511862 409.2627 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 8.75 3546.9 - 1.42E+06 - - - 1.1463 - 1.585 0.156 - 200.6 1 1 0 0.0009 7 0 0 0 8.54E+06 1.01E+07 - - - 1.6523 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18256.18256.2 0.00799 18-Jul K.MLLAISELNK.N sp|Q9H694|BICC1_HUMAN 1 1130.6369 4.03 14359 18256 2 1130.638806 566.3257 Protein bicaudal C homolog 1 OS=Homo sapiens OX=9606 GN=BICC1 PE=1 SV=2 5.75 3547.1 - 1.01E+06 - - - 1.6584 - 1.773 0.319 - 99.1 3 2 0 0.0019 10 0 0 0 4.65E+06 1.15E+06 - - - 2.7819 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18258.18258.2 0.000793 26-Nov K.VLIPSYAAGSIIGK.G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|F8W659|F8W659_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|F8VYI3|F8VYI3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|I3L2B5|I3L2B5_HUMAN" 8 1387.8075 2.45 14361 18258 2 1387.807379 694.911 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.56 3547.4 - 803602 - - - -0.0886 - 2.005 0.501 - 194.1 1 2 0 -0.0001 14 0 0 0 9.43E+06 3.85E+06 - - - 4.487 1 230117_WJC_METTL3_WT_vs_EV_F02.18259.18259.2 2.85E-08 13/24 -.MLSEVLLVSAPGK[136.11].V "sp|Q03426|KIME_HUMAN,tr|F5GXC0|F5GXC0_HUMAN,tr|F5H163|F5H163_HUMAN,tr|F5H092|F5H092_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|F5H368|F5H368_HUMAN,tr|A0A1W2PS16|A0A1W2PS16_HUMAN" 7 1350.7672 5.56 14362 18259 2 1350.76789 676.3909 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 5.75 3547.5 - 692828 - - - 0.4931 - 2.513 0.598 - 464.6 1 2 0 0.0007 13 0 0 0 2.26E+07 4.06E+06 - - - 5.8226 0.9427 230117_WJC_METTL3_WT_vs_EV_F02.18266.18266.2 0.0269 12-Jul H.ILLWDTR.N "sp|Q9BTV6|DPH7_HUMAN,sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 3 915.5178 0.45 14368 18266 2 915.518638 458.7662 Diphthine methyltransferase OS=Homo sapiens OX=9606 GN=DPH7 PE=1 SV=2 5.84 3548.4 - 4.76E+06 - - - 0.9131 - 1.511 0.322 - 218.1 1 1 0 0.0008 7 0 0 0 5.67E+08 1.25E+09 - - - 2.7269 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18268.18268.2 0.00966 14/20 K.LALDVEIATYR.K "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1262.6871 981.49 14369 18268 2 1262.690481 632.3508 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 3548.6 - 3.06E+06 - - - 2.7148 - 2.796 0.313 - 936.4 1 2 0 0.0034 11 0 0 0 4.52E+08 4.61E+05 - - - 4.1332 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.18270.18270.2 0.036 18-Dec R.ILELDQELIK.A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1212.6966 1.38 14371 18270 2 1212.69955 607.3556 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3548.8 - 1.23E+06 - - - 2.4697 - 2.093 0.254 - 366.9 1 2 0 0.003 10 0 0 0 5.91E+07 4.29E+07 - - - 2.9778 0.9953 230117_WJC_METTL3_WT_vs_EV_F02.18273.18273.2 0.399 16-Oct K.TLGILGLGR[166.11].L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 908.5683 2.16 14374 18273 2 908.570268 455.2914 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3549.2 - 740666 - - - 2.1969 - 1.55 0.114 - 328.1 1 2 0 0.002 9 0 0 0 5.34E+08 2.47E+08 - - - 1.1503 0.9685 230117_WJC_METTL3_WT_vs_EV_F02.18275.18275.2 0.0458 14-Jun R.FLFPEGIK[136.11].G "sp|O75891|AL1L1_HUMAN,sp|Q3SY69|AL1L2_HUMAN,tr|C9IZ36|C9IZ36_HUMAN,tr|A0A494C1M4|A0A494C1M4_HUMAN" 4 957.5415 1.24 14376 18275 2 957.53845 479.778 Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L1 PE=1 SV=2 6 3549.4 - 189543 - - - -3.1894 - 1.193 0.263 - 79.7 2 2 0 -0.0031 8 0 0 0 1.27E+07 1.02E+07 - - - 1.3803 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18276.18276.2 2.76E-05 26-Nov K.VLIPSYAAGSIIGK[136.11].G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|F8W659|F8W659_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|F8VYI3|F8VYI3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|I3L2B5|I3L2B5_HUMAN" 8 1395.8217 2.45 14377 18276 2 1395.820398 698.9181 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.56 3549.6 - 182210 - - - -0.9342 - 1.901 0.507 - 276.6 1 2 0 -0.0013 14 0 0 0 9.43E+06 3.85E+06 - - - 4.3973 0.8943 230117_WJC_METTL3_WT_vs_EV_F02.18278.18278.2 11.1 14-Jun R.LTFLNSFK.M "sp|Q9Y487|VPP2_HUMAN,sp|Q93050|VPP1_HUMAN,tr|F5H1T6|F5H1T6_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 5 968.5331 0.66 14379 18278 2 968.536044 485.2738 V-type proton ATPase 116 kDa subunit a2 OS=Homo sapiens OX=9606 GN=ATP6V0A2 PE=1 SV=2 8.75 3549.8 - 121711 - - - 3.0211 - 1.094 0.015 - 57.8 2 2 0 0.0029 8 0 0 0 2.41E+06 3.63E+06 - - - -0.7126 0.9913 230117_WJC_METTL3_WT_vs_EV_F02.18281.18281.2 2.1 16-Oct K.TLGILGLGR.L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 898.56 2.16 14380 18281 2 898.564232 450.2873 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3550.2 - 3.37E+06 - - - 4.7075 - 1.769 0.172 - 332.9 1 2 0 0.0042 9 0 0 0 5.35E+08 2.48E+08 - - - 1.9603 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.18283.18283.2 0.247 14-May R.IGVMSLIR.K "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 887.5263 1.46 14382 18283 2 887.527246 444.7704 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 3550.4 - 2.79E+06 - - - 1.1121 - 1.222 0.266 - 62 1 2 0 0.001 8 0 0 0 4.02E+07 2.75E+07 - - - 1.61 1 230117_WJC_METTL3_WT_vs_EV_F02.18284.18284.2 0.0127 22-Oct K.IPGIIIAASAVR.A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1179.7339 2.4 14383 18284 2 1179.741689 590.8742 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3550.5 - 1.08E+06 - - - 6.5659 - 2.287 0.468 - 330.5 1 2 0 0.0077 12 0 0 0 8.47E+07 3.53E+07 - - - 4.6718 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.18285.18285.2 0.0275 16-Aug R.YYIDADLLR[166.11].E sp|Q7Z3B4|NUP54_HUMAN 1 1150.5898 2.02 14384 18285 2 1150.592378 576.3022 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.21 3550.5 - 1.05E+06 - - - 2.2449 - 1.606 0.329 - 189.7 1 2 0 0.0026 9 0 0 0 7.93E+07 3.93E+07 - - - 2.8408 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18286.18286.2 0.000962 20-Nov R.LGIPDAVSYIK.K sp|O94874|UFL1_HUMAN 1 1174.6598 2.5 14385 18286 2 1174.661933 588.3372 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.83 3550.7 - 995879 - - - 1.8371 - 1.984 0.452 - 212.1 1 2 0 0.0022 11 0 0 0 3.36E+07 1.34E+07 - - - 4.2322 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18287.18287.2 0.00326 14-Aug R.VPTIFPLR[166.11].G sp|Q96EK4|THA11_HUMAN 1 951.5781 38.14 14386 18287 2 951.580106 476.7963 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 9.72 3550.8 - 659056 - - - 2.0997 - 1.683 0.404 - 237.9 1 2 0 0.002 8 0 0 0 5.23E+08 1.37E+07 - - - 3.5944 0.9954 230117_WJC_METTL3_WT_vs_EV_F02.18288.18288.2 0.00597 20-Nov K.LALDMEISAYR.K "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN" 2 1280.6435 1.68 14387 18288 2 1280.651489 641.329 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.37 3550.9 - 432410 - - - 6.2594 - 2.488 0.377 - 591 1 2 0 0.008 11 0 0 0 1.46E+07 8.73E+06 - - - 4.2888 1 230117_WJC_METTL3_WT_vs_EV_F02.18289.18289.2 0.00314 14/22 K.IPGIIIAASAVR[166.11].A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1189.7422 2.43 14388 18289 2 1189.751079 595.8784 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3551.1 - 423753 - - - 7.452 - 2.78 0.479 - 735.6 1 2 0 0.0089 12 0 0 0 8.38E+07 3.45E+07 - - - 5.2664 0.9459 230117_WJC_METTL3_WT_vs_EV_F02.18291.18291.2 0.721 20-Aug K.NLIDAGVDALR[166.11].V "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1165.6331 1.21 14390 18291 2 1165.629772 583.8238 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.21 3551.3 - 226730 - - - -2.8182 - 1.479 0.109 - 131.7 2 2 0 -0.0033 11 0 0 0 5.12E+06 4.22E+06 - - - 0.7693 0.9242 230117_WJC_METTL3_WT_vs_EV_F02.18296.18296.2 10.5 14-Jul K.MLLVDELR.D "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 987.5423 0.95 14393 18296 2 987.541742 494.7784 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 4.37 3552 - 2.04E+07 - - - -0.5681 - 1.169 0.009 - 180.6 1 2 0 -0.0006 8 0 0 0 1.38E+08 1.45E+08 - - - -0.4218 0.999 230117_WJC_METTL3_WT_vs_EV_F02.18299.18299.2 0.657 12-Aug K.ILVDLLK.L "sp|Q6P582|MZT2A_HUMAN,sp|Q6NZ67|MZT2B_HUMAN,tr|H7C202|H7C202_HUMAN,tr|B8ZZ87|B8ZZ87_HUMAN,tr|A0A494C0V9|A0A494C0V9_HUMAN,tr|H7BZ50|H7BZ50_HUMAN,tr|H7C173|H7C173_HUMAN" 7 812.5371 2.36 14396 18299 2 812.539052 407.2758 Mitotic-spindle organizing protein 2A OS=Homo sapiens OX=9606 GN=MZT2A PE=1 SV=2 5.84 3552.2 - 1.60E+06 - - - 2.3519 - 1.849 0.222 - 173.6 1 2 0 0.0019 7 0 0 0 2.99E+07 1.27E+07 - - - 2.6276 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.18300.18300.3 0.000417 Dec-44 R.FLAVGLVDNTVR.L sp|Q15393|SF3B3_HUMAN 1 1302.7296 3.02 14397 18300 3 1302.733924 435.2505 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3552.3 - 1.38E+06 - - - 3.3299 - 2.016 0.434 - 159.4 1 2 0 0.0043 12 0 0 0 2.11E+07 6.98E+06 - - - 5.3209 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.18304.18304.2 0.0873 12-Aug K.ILVDLLK[136.11].L "sp|Q6P582|MZT2A_HUMAN,sp|Q6NZ67|MZT2B_HUMAN,tr|H7C202|H7C202_HUMAN,tr|B8ZZ87|B8ZZ87_HUMAN,tr|A0A494C0V9|A0A494C0V9_HUMAN,tr|H7BZ50|H7BZ50_HUMAN,tr|H7C173|H7C173_HUMAN" 7 820.5513 2.36 14401 18304 2 820.552351 411.2829 Mitotic-spindle organizing protein 2A OS=Homo sapiens OX=9606 GN=MZT2A PE=1 SV=2 5.84 3552.9 - 838947 - - - 1.2309 - 1.775 0.232 - 139.6 1 2 0 0.001 7 0 0 0 2.99E+07 1.27E+07 - - - 2.5724 1 230117_WJC_METTL3_WT_vs_EV_F02.18308.18308.2 4.75E-06 28-Oct R.LGALQGDPEALTLYR.E sp|Q9P253|VPS18_HUMAN 1 1615.857 11.42 14405 18308 2 1615.858866 808.9358 Vacuolar protein sorting-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=VPS18 PE=1 SV=2 4.37 3553.4 - 240137 - - - 1.1721 - 2.14 0.53 - 215.5 1 2 0 0.0019 15 0 0 0 2.74E+06 2.40E+05 - - - 4.8255 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18312.18312.2 0.00167 22-Nov K.LIVDPALDPALR.R "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN,tr|C9J2Z9|C9J2Z9_HUMAN" 3 1291.75 2.68 14407 18312 2 1291.753499 646.8823 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.21 3553.9 - 977412 - - - 2.7188 - 1.933 0.425 - 361.3 1 2 0 0.0035 12 0 0 0 3.94E+07 1.47E+07 - - - 3.9131 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.18314.18314.2 0.173 16-Nov R.LALILC[160.03]VTK.A sp|P31944|CASPE_HUMAN 1 1029.6256 8.74 14409 18314 2 1029.627641 515.8201 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 8.22 3554 - 910831 - - - 1.9444 - 2.018 0.159 - 209.1 1 2 0 0.002 9 0 0 0 1.68E+07 1.93E+06 - - - 2.246 0.9421 230117_WJC_METTL3_WT_vs_EV_F02.18315.18315.2 0.00631 16-Aug N.LLLNYGLYR.K "sp|Q92769|HDAC2_HUMAN,sp|Q13547|HDAC1_HUMAN,tr|E5RHE7|E5RHE7_HUMAN,tr|E5RGV4|E5RGV4_HUMAN,tr|H3BM24|H3BM24_HUMAN,tr|E5RJ04|E5RJ04_HUMAN,tr|E5RG37|E5RG37_HUMAN,tr|E5RH52|E5RH52_HUMAN,tr|E5RK19|E5RK19_HUMAN,tr|E5RFP9|E5RFP9_HUMAN,tr|E5RFI6|E5RFI6_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 12 1123.639 1.4 14410 18315 2 1123.640664 562.8268 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 8.59 3554.1 - 902922 - - - 1.4987 - 1.82 0.257 - 186.5 1 1 0 0.0017 9 0 0 0 1.48E+07 1.06E+07 - - - 2.6711 0.9676 230117_WJC_METTL3_WT_vs_EV_F02.18317.18317.2 0.00492 20-Nov R.LLDLVVQPVPR.P sp|Q8WYP5|ELYS_HUMAN 1 1247.7602 1.41 14412 18317 2 1247.763083 624.8874 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.84 3554.4 - 325647 - - - 2.3442 - 2.287 0.357 - 534.7 1 1 0 0.0029 11 0 0 0 1.65E+07 1.17E+07 - - - 3.9148 0.9693 230117_WJC_METTL3_WT_vs_EV_F02.18319.18319.2 0.0774 22-Oct L.PLIPIVVEQTGR.G sp|Q16740|CLPP_HUMAN 1 1320.7765 1.7 14414 18319 2 1320.777794 661.3955 "ATP-dependent Clp protease proteolytic subunit, mitochondrial OS=Homo sapiens OX=9606 GN=CLPP PE=1 SV=1" 6.43 3554.6 - 195235 - - - 0.9525 - 2.044 0.366 - 244.7 1 1 0 0.0013 12 0 0 0 1.08E+07 6.33E+06 - - - 3.6249 1 230117_WJC_METTL3_WT_vs_EV_F02.18325.18325.2 2.25E-05 22-Nov R.FLAVGLVDNTVR[166.11].L sp|Q15393|SF3B3_HUMAN 1 1312.7379 1.13 14419 18325 2 1312.740385 657.3762 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3555.4 - 9.25E+06 - - - 1.9265 - 2.278 0.532 - 462.3 1 2 0 0.0025 12 0 0 0 1.82E+08 1.61E+08 - - - 5.1358 0.9839 230117_WJC_METTL3_WT_vs_EV_F02.18332.18332.2 1.95 16-Jun R.IAYSLLGLK.D sp|P29317|EPHA2_HUMAN 1 976.5957 2.25 14425 18332 2 976.598689 489.3051 Ephrin type-A receptor 2 OS=Homo sapiens OX=9606 GN=EPHA2 PE=1 SV=2 8.59 3556.1 - 69565.5 - - - 3.0422 - 1.381 0.124 - 65.2 5 2 0 0.003 9 0 0 0 1.69E+06 7.50E+05 - - - 0.5776 0.9078 230117_WJC_METTL3_WT_vs_EV_F02.18335.18335.2 0.00715 18-Sep S.GVAVSDGVIK.V "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PS23|E9PS23_HUMAN" 4 943.5338 2.02 14426 18335 2 943.535243 472.7742 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 5.84 3556.5 - 1.88E+06 - - - 1.4806 - 1.541 0.256 - 164.5 1 1 0 0.0014 10 0 0 0 8.61E+08 4.27E+08 - - - 2.1384 1 230117_WJC_METTL3_WT_vs_EV_F02.18337.18337.2 0.00015 15/22 H.IISELILTAQER.D sp|Q96I24|FUBP3_HUMAN 1 1384.7926 1.78 14428 18337 2 1384.797284 693.4036 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3556.8 - 590189 - - - 3.3969 - 2.631 0.487 - 870 1 1 0 0.0047 12 0 0 0 1.50E+07 8.45E+06 - - - 5.1818 0.9753 230117_WJC_METTL3_WT_vs_EV_F02.18339.18339.2 0.00449 14/22 H.IISELILTAQER[166.11].D sp|Q96I24|FUBP3_HUMAN 1 1394.8009 1.78 14430 18339 2 1394.803835 698.4077 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3557 - 434649 - - - 2.1401 - 2.691 0.366 - 737.2 1 1 0 0.003 12 0 0 0 1.50E+07 8.45E+06 - - - 4.348 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.18345.18345.2 0.809 14-Jul R.SSLLLGFR.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 891.5178 0.84 14435 18345 2 891.520292 446.7662 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 9.47 3557.8 - 5.14E+06 - - - 2.793 - 1.8 0.202 - 198.2 1 2 0 0.0025 8 0 0 0 5.86E+07 6.94E+07 - - - 2.3049 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.18351.18351.2 8.70E-05 18-Sep R.YLYTLVITDK[136.11].E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1235.6893 1.47 14440 18351 2 1235.694159 618.8519 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3558.4 - 425974 - - - 3.9395 - 2.078 0.375 - 216.7 1 2 0 0.0049 10 0 0 0 1.23E+09 8.35E+08 - - - 3.8508 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.18360.18360.2 0.315 12-Aug K.MIADFLR.E "sp|Q96R72|OR4K3_HUMAN,sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 4 864.4528 2.31 14447 18360 2 864.4541 433.2337 Olfactory receptor 4K3 OS=Homo sapiens OX=9606 GN=OR4K3 PE=3 SV=3 5.59 3559.5 - 976073 - - - 1.5513 - 1.48 0.226 - 273.7 1 2 0 0.0013 7 0 0 0 5.14E+07 2.23E+07 - - - 1.952 0.9432 230117_WJC_METTL3_WT_vs_EV_F02.18362.18362.2 6.32 12-Jun K.MIADFLR[166.11].E "sp|Q96R72|OR4K3_HUMAN,sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 4 874.461 2.43 14449 18362 2 874.465076 438.2378 Olfactory receptor 4K3 OS=Homo sapiens OX=9606 GN=OR4K3 PE=3 SV=3 5.59 3559.7 - 492817 - - - 4.628 - 1.228 0.097 - 144.9 1 2 0 0.004 7 0 0 0 5.04E+07 2.07E+07 - - - 0.407 0.9385 230117_WJC_METTL3_WT_vs_EV_F02.18363.18363.2 0.00158 13/20 R.LLDLVVQPVPR[166.11].P sp|Q8WYP5|ELYS_HUMAN 1 1257.7684 1.41 14450 18363 2 1257.772829 629.8915 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.84 3559.9 - 460922 - - - 3.4991 - 2.425 0.337 - 891.2 1 1 0 0.0044 11 0 0 0 1.65E+07 1.17E+07 - - - 3.9251 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.18364.18364.2 0.308 14-Jul K.DVIEEYFK.C sp|P25398|RS12_HUMAN 1 1041.5019 2.61 14451 18364 2 1041.505518 521.7582 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.14 3560 - 432411 - - - 3.495 - 1.665 0.361 - 159.8 1 2 0 0.0036 8 0 0 0 1.02E+07 3.90E+06 - - - 3.2438 0.995 230117_WJC_METTL3_WT_vs_EV_F02.18365.18365.2 0.208 14-Sep R.LEELQLFK.N "sp|Q96PZ0|PUS7_HUMAN,sp|O95025|SEM3D_HUMAN,sp|O15041|SEM3E_HUMAN,tr|A0A2R8YCX5|A0A2R8YCX5_HUMAN,tr|E7EUH7|E7EUH7_HUMAN" 5 1018.5699 0.53 14452 18365 2 1018.574725 510.2922 Pseudouridylate synthase 7 homolog OS=Homo sapiens OX=9606 GN=PUS7 PE=1 SV=2 4.53 3560.1 - 301497 - - - 4.739 - 1.715 0.254 - 190.8 1 2 0 0.0048 8 0 0 0 9.43E+06 1.76E+07 - - - 2.5424 0.9906 230117_WJC_METTL3_WT_vs_EV_F02.18373.18373.2 0.717 14-Jun K.DLYSALIK.L sp|O75844|FACE1_HUMAN 1 921.5171 1.08 14458 18373 2 921.517458 461.7658 CAAX prenyl protease 1 homolog OS=Homo sapiens OX=9606 GN=ZMPSTE24 PE=1 SV=2 5.83 3561 - 839170 - - - 0.3516 - 1.126 0.172 - 103.2 1 2 0 0.0003 8 0 0 0 4.47E+07 4.15E+07 - - - 0.6692 1 230117_WJC_METTL3_WT_vs_EV_F02.18378.18378.2 4.22E-06 16-Nov K.YMAEALLLR.A sp|O94826|TOM70_HUMAN 1 1078.5845 1.77 14462 18378 2 1078.587119 540.2995 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 6 3561.5 - 891448 - - - 2.4263 - 2.129 0.486 - 321.9 1 2 0 0.0026 9 0 0 0 1.74E+07 9.84E+06 - - - 4.8159 1 230117_WJC_METTL3_WT_vs_EV_F02.18379.18379.2 0.00226 20-Dec R.ILDVGFEEELK[136.11].Q "sp|Q9NVP1|DDX18_HUMAN,tr|H7C452|H7C452_HUMAN" 2 1298.6849 0.93 14463 18379 2 1298.688302 650.3497 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 4 3561.7 - 2.10E+06 - - - 2.5934 - 2.199 0.464 - 456.6 1 2 0 0.0034 11 0 0 0 2.57E+07 2.75E+07 - - - 4.5988 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.18381.18381.2 0.109 18-Aug K.LWTMPISSVR[166.11].F "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1198.6408 2.02 14465 18381 2 1198.641648 600.3277 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3561.9 - 547895 - - - 0.72 - 1.589 0.143 - 195.5 1 2 0 0.0009 10 0 0 0 1.26E+07 6.25E+06 - - - 1.3896 0.9952 230117_WJC_METTL3_WT_vs_EV_F02.18382.18382.2 0.0555 20-Aug K.GLLPTPDEFPR.F sp|Q9C0J8|WDR33_HUMAN 1 1240.6452 1.14 14466 18382 2 1240.644405 621.3299 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 4.37 3562.1 - 1.05E+06 - - - -0.6311 - 1.182 0.288 - 111.9 1 2 0 -0.0008 11 0 0 0 1.11E+07 9.75E+06 - - - 1.6203 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.18383.18383.2 0.0632 14-Jul K.IGGIFAFK.V "sp|P22307|SCP2_HUMAN,tr|H0YF61|H0YF61_HUMAN" 2 851.4905 1.46 14467 18383 2 851.48967 426.7525 Sterol carrier protein 2 OS=Homo sapiens OX=9606 GN=SCP2 PE=1 SV=2 8.75 3562.2 - 461344 - - - -1.0041 - 1.537 0.223 - 86.7 1 2 0 -0.0009 8 0 0 0 7.67E+06 5.26E+06 - - - 1.9842 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18384.18384.2 1.22E-05 22-Aug R.LVPVSFEDPEFK.S tr|F5GXE4|F5GXE4_HUMAN 1 1405.7129 6.08 14468 18384 2 1405.713302 703.8637 Arginyl-tRNA--protein transferase 1 OS=Homo sapiens OX=9606 GN=ATE1 PE=1 SV=1 4.14 3562.3 - 237025 - - - 0.2625 - 1.763 0.479 - 96.8 1 2 0 0.0004 12 0 0 0 3.60E+06 5.92E+05 - - - 4.0707 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18389.18389.2 0.00752 16-Aug K.GIFLGDQWR.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1090.556 2.43 14471 18389 2 1090.557662 546.2853 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3562.9 - 1.00E+07 - - - 1.5432 - 1.454 0.426 - 226.3 1 2 0 0.0017 9 0 0 0 1.83E+08 7.54E+07 - - - 3.2698 0.9957 230117_WJC_METTL3_WT_vs_EV_F02.18390.18390.2 0.107 16-Apr R.ILFLDPSGK[136.11].V sp|O95881|TXD12_HUMAN 1 996.5735 1.11 14472 18390 2 996.575685 499.294 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3562.9 - 9.30E+06 - - - 2.1594 - 0.891 0.34 - 43.2 1 2 0 0.0022 9 0 0 0 9.15E+08 8.26E+08 - - - 1.2177 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18399.18399.2 0.00202 16-Sep K.GIFLGDQWR[166.11].D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1100.5642 2.42 14479 18399 2 1100.566943 551.2894 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3563.7 - 3.71E+06 - - - 2.4478 - 1.668 0.415 - 293.4 1 2 0 0.0027 9 0 0 0 1.82E+08 7.52E+07 - - - 3.5855 0.9776 230117_WJC_METTL3_WT_vs_EV_F02.18400.18400.2 0.000125 18-Nov R.IPLNPYLNLH.S "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 1192.6604 - 14480 18400 2 1192.661463 597.3375 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.74 3563.8 - 747657 - - - 0.8544 - 2.111 0.436 - 450.4 1 1 0 0.001 10 0 0 0 - - - - - 4.3465 1 230117_WJC_METTL3_WT_vs_EV_F02.18402.18402.2 0.000238 20-Nov R.ILMLGLDAAGK[136.11].T sp|P62330|ARF6_HUMAN 1 1108.6406 0.76 14482 18402 2 1108.643009 555.3276 ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2 5.84 3564 - 410085 - - - 2.2027 - 2.189 0.482 - 233.1 1 2 0 0.0024 11 0 0 0 9.36E+06 1.24E+07 - - - 4.7197 1 230117_WJC_METTL3_WT_vs_EV_F02.18403.18403.2 2.38E-08 26-Nov K.FYGPEGPYGVFAGR.D sp|O00264|PGRC1_HUMAN 1 1515.7147 1.49 14483 18403 2 1515.71522 758.8646 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3564.2 - 312148 - - - 0.3668 - 2.274 0.631 - 399.5 1 2 0 0.0006 14 0 0 0 5.17E+07 3.46E+07 - - - 5.763 1 230117_WJC_METTL3_WT_vs_EV_F02.18404.18404.2 5.17E-06 26-Dec K.FYGPEGPYGVFAGR[166.11].D sp|O00264|PGRC1_HUMAN 1 1525.7229 1.49 14484 18404 2 1525.725646 763.8687 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3564.3 - 264412 - - - 1.7775 - 1.877 0.556 - 194.5 1 2 0 0.0027 14 0 0 0 5.17E+07 3.46E+07 - - - 4.7269 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18405.18405.2 0.0149 16-Aug K.LEVDIPLVK.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1024.6168 2.57 14485 18405 2 1024.618881 513.3157 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3564.4 - 262362 - - - 1.9842 - 1.678 0.311 - 157 1 2 0 0.002 9 0 0 0 2.21E+08 8.62E+07 - - - 2.8349 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.18408.18408.2 0.0029 24-Jul R.LFLAGYDPTPTMR.D sp|O75436|VP26A_HUMAN 1 1480.7384 2.1 14488 18408 2 1480.73476 741.3765 Vacuolar protein sorting-associated protein 26A OS=Homo sapiens OX=9606 GN=VPS26A PE=1 SV=2 5.84 3564.8 - 171685 - - - -2.4825 - 1.745 0.381 - 148.7 1 2 0 -0.0037 13 0 0 0 1.54E+06 7.31E+05 - - - 3.2828 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.18413.18413.2 7.05E-05 22-Oct K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 393.59 14491 18413 2 1382.679822 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3565.3 - 1.23E+06 - - - -2.3201 - 2.073 0.464 - 264.5 1 2 0 -0.0032 12 0 0 0 2.39E+07 6.07E+04 - - - 4.3852 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18422.18422.2 0.000853 16-Sep K.LEVDIPLVK[136.11].S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1032.631 2.41 14498 18422 2 1032.63199 517.3228 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3566.4 - 2.04E+06 - - - 0.9122 - 1.919 0.444 - 216.7 1 2 0 0.0009 9 0 0 0 2.07E+08 8.60E+07 - - - 4.2058 0.9962 230117_WJC_METTL3_WT_vs_EV_F02.18426.18426.2 0.911 18-May R.VIALGLPVPR[166.11].Y sp|A3KMH1|VWA8_HUMAN 1 1043.6731 1.21 14502 18426 2 1043.674509 522.8438 von Willebrand factor A domain-containing protein 8 OS=Homo sapiens OX=9606 GN=VWA8 PE=1 SV=2 9.72 3566.9 - 302351 - - - 1.3778 - 1.504 0.223 - 38.1 28 2 0 0.0014 10 0 0 0 3.98E+06 3.29E+06 - - - 1.1804 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.18431.18431.3 0.000386 18/80 R.KHAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2325.1812 1.41 14505 18431 3 2325.188879 776.0677 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3567.5 - 73162.2 - - - 3.2944 - 3.277 0.51 - 331.7 1 2 0 0.0077 21 0 0 0 5.24E+06 3.72E+06 - - - 7.0695 0.999 230117_WJC_METTL3_WT_vs_EV_F02.18432.18432.2 0.00156 14-Sep R.GFGFVQFK[136.11].N "sp|Q9NW13|RBM28_HUMAN,tr|C9JE21|C9JE21_HUMAN" 2 936.4949 0.75 14506 18432 2 936.497234 469.2547 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 8.75 3567.6 - 219229 - - - 2.504 - 1.524 0.332 - 173.7 1 2 0 0.0023 8 0 0 0 1.97E+07 2.64E+07 - - - 2.7632 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18433.18433.2 0.0179 20-Sep R.MLDMGFEPQIR[166.11].R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1345.6398 1.23 14507 18433 2 1345.641402 673.8272 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3567.8 - 181197 - - - 1.192 - 1.881 0.384 - 299.2 1 2 0 0.0016 11 0 0 0 1.77E+08 1.44E+08 - - - 3.5859 0.9864 230117_WJC_METTL3_WT_vs_EV_F02.18436.18436.2 0.0863 12-Aug R.SILEYLR[166.11].V sp|Q8N1G4|LRC47_HUMAN 1 902.5101 1.51 14508 18436 2 902.509435 452.2623 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 5.72 3568.1 - 2.28E+06 - - - -0.7235 - 1.402 0.098 - 203.2 1 2 0 -0.0007 7 0 0 0 5.90E+07 3.92E+07 - - - 0.8353 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.18437.18437.2 0.512 14-Aug R.EMVLEIIR[166.11].E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1011.5662 1.38 14509 18437 2 1011.567245 506.7904 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3568.2 - 1.26E+06 - - - 1.0103 - 1.66 0.178 - 248.4 1 2 0 0.001 8 0 0 0 5.16E+08 3.74E+08 - - - 1.8839 1 230117_WJC_METTL3_WT_vs_EV_F02.18440.18440.2 2.49E-05 20-Sep R.MLDMGFEPQIR.R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1335.6315 1.23 14512 18440 2 1335.633029 668.823 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3568.6 - 573455 - - - 1.1238 - 2.034 0.503 - 316.1 1 2 0 0.0015 11 0 0 0 1.77E+08 1.44E+08 - - - 4.6764 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18442.18442.2 0.00181 18-Sep K.FYALDPSFPR[166.11].M sp|Q08J23|NSUN2_HUMAN 1 1221.6058 1.35 14514 18442 2 1221.606474 611.8102 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3568.9 - 553269 - - - 0.5689 - 1.566 0.393 - 274.2 1 2 0 0.0007 10 0 0 0 2.49E+07 1.85E+07 - - - 3.1954 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.18448.18448.2 0.106 16-Oct K.ILLITEDLK.N sp|Q08752|PPID_HUMAN 1 1056.6431 2.93 14518 18448 2 1056.644919 529.3288 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 4.37 3569.6 - 590626 - - - 1.7565 - 1.887 0.194 - 293.5 1 2 0 0.0019 9 0 0 0 3.97E+07 1.36E+07 - - - 2.3104 0.9856 230117_WJC_METTL3_WT_vs_EV_F02.18449.18449.2 0.93 12-Jul R.FQLQLLR.E sp|Q9P2R3|ANFY1_HUMAN 1 916.5494 0.85 14519 18449 2 916.55074 459.282 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 9.75 3569.8 - 869206 - - - 1.4216 - 1.251 0.064 - 201.5 1 2 0 0.0013 7 0 0 0 1.35E+07 1.59E+07 - - - 0.2229 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.18450.18450.2 0.251 14-Sep K.VALLLLEK.E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 897.5899 1.29 14520 18450 2 897.590923 449.8022 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3569.8 - 619294 - - - 1.1341 - 1.564 0.186 - 272.6 1 2 0 0.001 8 0 0 0 2.74E+07 2.13E+07 - - - 1.7634 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18458.18458.2 0.0049 14-Sep K.MAILQIMK[136.11].E "sp|Q13263|TIF1B_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 2 954.5486 1.49 14526 18458 2 954.550485 478.2816 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 8.5 3570.9 - 8.20E+06 - - - 1.9957 - 1.83 0.321 - 336.3 1 2 0 0.0019 8 0 0 0 1.20E+08 8.03E+07 - - - 3.2339 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18459.18459.2 0.000144 22-Nov K.GLTPSQIGVILR[166.11].D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1262.7586 0.86 14527 18459 2 1262.760131 632.3866 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3570.9 - 3.31E+06 - - - 1.2188 - 2.33 0.366 - 499.2 1 2 0 0.0015 12 0 0 0 8.53E+07 9.91E+07 - - - 3.9694 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.18460.18460.2 1.53 14-Jul R.EMVLEIIR.E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1001.558 1.38 14528 18460 2 1001.558537 501.7863 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3571 - 1.66E+07 - - - 0.5831 - 1.556 0.178 - 219.4 1 2 0 0.0006 8 0 0 0 5.16E+08 3.74E+08 - - - 1.6889 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18461.18461.2 1.02E-05 22-Nov K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 0.86 14529 18461 2 1252.75023 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3571 - 2.64E+06 - - - -0.0734 - 2.355 0.329 - 521 1 2 0 -0.0001 12 0 0 0 8.53E+07 9.91E+07 - - - 3.7247 0.9916 230117_WJC_METTL3_WT_vs_EV_F02.18462.18462.2 0.674 12-Jun R.FQLQLLR[166.11].E sp|Q9P2R3|ANFY1_HUMAN 1 926.5577 0.9 14530 18462 2 926.559079 464.2861 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 9.75 3571.1 - 2.18E+06 - - - 1.4807 - 1.364 0.078 - 88 1 2 0 0.0014 7 0 0 0 1.52E+07 1.69E+07 - - - 0.6003 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.18463.18463.2 0.00073 14-Aug K.VALLLLEK[136.11].E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 905.6041 1.29 14531 18463 2 905.60453 453.8093 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3571.2 - 2.17E+06 - - - 0.4693 - 2.201 0.108 - 190.6 1 2 0 0.0004 8 0 0 0 2.74E+07 2.13E+07 - - - 2.2179 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18466.18466.2 9.61E-05 20-Oct R.YFGPNLLNTVK[136.11].Q "sp|P62487|RPB7_HUMAN,tr|E9PIU7|E9PIU7_HUMAN,tr|E9PKH3|E9PKH3_HUMAN,tr|H0YEE4|H0YEE4_HUMAN" 4 1272.6958 1.04 14534 18466 2 1272.698209 637.3552 DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1 8.59 3571.5 - 582558 - - - 1.914 - 1.744 0.444 - 239.4 1 2 0 0.0024 11 0 0 0 6.45E+06 6.22E+06 - - - 3.8242 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.18471.18471.2 0.0186 14-Oct K.MAILQIMK.E "sp|Q13263|TIF1B_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 2 946.5344 1.49 14537 18471 2 946.537365 474.2745 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 8.5 3572.1 - 8.11E+06 - - - 3.1536 - 1.925 0.338 - 386.5 1 2 0 0.003 8 0 0 0 1.20E+08 8.03E+07 - - - 3.5118 0.9914 230117_WJC_METTL3_WT_vs_EV_F02.18472.18472.2 0.754 14-Jun R.GFGFVQFK.N "sp|Q9NW13|RBM28_HUMAN,tr|C9JE21|C9JE21_HUMAN" 2 928.4807 0.71 14538 18472 2 928.484096 465.2476 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 8.75 3572.2 - 1.53E+06 - - - 3.6694 - 1.094 0.277 - 82 1 2 0 0.0034 8 0 0 0 1.99E+07 2.79E+07 - - - 1.3568 1 230117_WJC_METTL3_WT_vs_EV_F02.18473.18473.2 6.28E-07 16-Oct K.LYMVLITTK.N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 3 1080.6253 1.54 14539 18473 2 1080.626902 541.3199 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 8.59 3572.3 - 1.63E+06 - - - 1.4788 - 1.946 0.525 - 341 1 2 0 0.0016 9 0 0 0 2.25E+07 1.46E+07 - - - 4.8443 0.9941 230117_WJC_METTL3_WT_vs_EV_F02.18475.18475.2 0.351 12-Jul R.DLFALAR.K sp|Q9Y4W6|AFG32_HUMAN 1 804.4494 1.25 14541 18475 2 804.451473 403.232 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.84 3572.5 - 749779 - - - 2.5918 - 1.286 0.175 - 223.3 1 2 0 0.0021 7 0 0 0 1.54E+07 1.24E+07 - - - 1.1299 0.9955 230117_WJC_METTL3_WT_vs_EV_F02.18476.18476.2 0.262 12-Jun R.DLFALAR[166.11].K sp|Q9Y4W6|AFG32_HUMAN 1 814.4577 1.24 14542 18476 2 814.458743 408.2361 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.84 3572.7 - 665424 - - - 1.3322 - 1.138 0.217 - 171 1 2 0 0.0011 7 0 0 0 1.54E+07 1.24E+07 - - - 1.053 1 230117_WJC_METTL3_WT_vs_EV_F02.18478.18478.2 4.81E-07 20-Sep K.FGEPVLAGFAR.S sp|O15067|PUR4_HUMAN 1 1162.6135 2.62 14544 18478 2 1162.619231 582.314 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 6 3572.9 - 470625 - - - 4.9346 - 2.086 0.532 - 188 1 2 0 0.0057 11 0 0 0 5.73E+07 2.18E+07 - - - 4.9576 0.9944 230117_WJC_METTL3_WT_vs_EV_F02.18479.18479.2 2.45 18-Nov R.LLDEQFAVLR.G sp|O75146|HIP1R_HUMAN 1 1202.6659 0.36 14545 18479 2 1202.67396 602.3402 Huntingtin-interacting protein 1-related protein OS=Homo sapiens OX=9606 GN=HIP1R PE=1 SV=2 4.37 3573.1 - 229142 - - - 6.6827 - 2.358 0.413 - 339.8 1 2 0 0.008 10 0 0 0 4.33E+06 1.20E+07 - - - 4.4833 0.9836 230117_WJC_METTL3_WT_vs_EV_F02.18482.18482.2 0.428 12-May R.EIFITFR.V sp|Q96EY1|DNJA3_HUMAN 1 924.5069 1.79 14546 18482 2 924.510684 463.2607 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.1 3573.5 - 869546 - - - 4.0897 - 1.234 0.213 - 78.3 3 2 0 0.0038 7 0 0 0 3.77E+07 2.10E+07 - - - 1.0661 1 230117_WJC_METTL3_WT_vs_EV_F02.18486.18486.2 2.29E-06 13/22 K.AFAVGVQQVLLK.V sp|O95373|IPO7_HUMAN 1 1271.7602 1.86 14550 18486 2 1271.762019 636.8874 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 8.8 3574 - 251649 - - - 1.4633 - 2.578 0.597 - 567.7 1 2 0 0.0019 12 0 0 0 3.24E+07 1.74E+07 - - - 5.9416 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.18488.18488.2 0.546 16-Jun R.LLYGMALVR[166.11].F "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3R6|A0A7I2V3R6_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V4V0|A0A7I2V4V0_HUMAN,tr|A0A7I2V5R7|A0A7I2V5R7_HUMAN,tr|A0A7I2V653|A0A7I2V653_HUMAN,tr|A0A7I2YQI7|A0A7I2YQI7_HUMAN" 7 1044.6029 1.38 14552 18488 2 1044.604965 523.3087 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 8.75 3574.2 - 193134 - - - 1.9366 - 1.466 0.253 - 74.4 2 2 0 0.002 9 0 0 0 1.90E+07 1.38E+07 - - - 1.8813 1 230117_WJC_METTL3_WT_vs_EV_F02.18489.18489.2 0.000129 22-Oct K.AFAVGVQQVLLK[136.11].V sp|O95373|IPO7_HUMAN 1 1279.7744 1.86 14553 18489 2 1279.77803 640.8945 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 8.8 3574.4 - 164042 - - - 2.8693 - 2.216 0.491 - 312.8 1 2 0 0.0037 12 0 0 0 3.24E+07 1.74E+07 - - - 4.76 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18492.18492.2 0.000966 18-Aug K.FYALDPSFPR.M sp|Q08J23|NSUN2_HUMAN 1 1211.5975 1.74 14555 18492 2 1211.598576 606.806 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3574.7 - 766934 - - - 0.8807 - 1.514 0.457 - 225.4 1 2 0 0.0011 10 0 0 0 2.68E+07 1.54E+07 - - - 3.5738 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.18496.18496.2 0.025 16-Oct R.SLIAEVLVK.L sp|O95969|SG1D2_HUMAN 1 970.6063 999 14558 18496 2 970.609098 486.3104 Secretoglobin family 1D member 2 OS=Homo sapiens OX=9606 GN=SCGB1D2 PE=2 SV=1 5.72 3575.2 - 887462 - - - 2.9002 - 1.712 0.271 - 243.8 1 2 0 0.0028 9 0 0 0 3.37E+07 0.00E+00 - - - 2.5972 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18504.18504.2 0.00204 16-Oct R.LYSVSYLLK[136.11].D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1092.631 0.69 14564 18504 2 1092.633214 547.3228 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.5 3576.2 - 1.77E+06 - - - 1.9824 - 2.064 0.452 - 233.5 1 2 0 0.0022 9 0 0 0 5.37E+07 7.83E+07 - - - 4.4752 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18505.18505.2 0.00497 18-Sep K.ALQEFDLALR.G "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1174.6346 0.67 14565 18505 2 1174.637565 588.3246 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 4.37 3576.4 - 769467 - - - 2.5046 - 1.855 0.32 - 238.7 1 2 0 0.0029 10 0 0 0 1.30E+07 1.96E+07 - - - 3.1283 0.8503 230117_WJC_METTL3_WT_vs_EV_F02.18506.18506.2 0.664 14-Sep V.ILSILLSK[136.11].A "sp|Q6UXB4|CLC4G_HUMAN,sp|Q02040|AK17A_HUMAN,tr|A0A7I2V4C7|A0A7I2V4C7_HUMAN,tr|M0R277|M0R277_HUMAN,tr|A0A7I2V4U5|A0A7I2V4U5_HUMAN" 5 893.6041 1.04 14566 18506 2 893.606873 447.8093 C-type lectin domain family 4 member G OS=Homo sapiens OX=9606 GN=CLEC4G PE=1 SV=1 8.75 3576.5 - 634598 - - - 3.0976 - 1.722 0.213 - 180.2 1 1 0 0.0028 8 0 0 0 1.34E+07 1.29E+07 - - - 2.2525 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.18507.18507.2 0.00131 18-Jul K.VFLSGMPELR.L "sp|Q9Y6Q5|AP1M2_HUMAN,sp|Q9BXS5|AP1M1_HUMAN,tr|E7ENJ6|E7ENJ6_HUMAN,tr|K7EJL1|K7EJL1_HUMAN,tr|K7EJJ1|K7EJJ1_HUMAN,tr|K7EMG5|K7EMG5_HUMAN,tr|K7EPR4|K7EPR4_HUMAN" 7 1147.606 1.1 14567 18507 2 1147.609536 574.8103 AP-1 complex subunit mu-2 OS=Homo sapiens OX=9606 GN=AP1M2 PE=1 SV=4 5.97 3576.6 - 553388 - - - 3.1117 - 1.65 0.311 - 138 1 2 0 0.0036 10 0 0 0 9.40E+06 8.55E+06 - - - 2.7347 1 230117_WJC_METTL3_WT_vs_EV_F02.18514.18514.2 1.81E-05 13/22 R.MGLAISLVATEK[136.11].E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 1239.6988 1.35 14572 18514 2 1239.694189 620.8567 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.75 3577.6 - 1.37E+06 - - - -3.7275 - 2.625 0.486 - 492.6 1 2 0 -0.0046 12 0 0 0 5.16E+07 3.83E+07 - - - 5.1684 0.9966 230117_WJC_METTL3_WT_vs_EV_F02.18515.18515.2 0.438 12-Jun R.EIFITFR[166.11].V sp|Q96EY1|DNJA3_HUMAN 1 934.5152 1.79 14573 18515 2 934.516587 468.2649 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.1 3577.6 - 2.49E+06 - - - 1.5131 - 1.252 0.207 - 146.3 1 2 0 0.0014 7 0 0 0 3.73E+07 2.08E+07 - - - 1.2816 0.999 230117_WJC_METTL3_WT_vs_EV_F02.18516.18516.2 0.0496 18-Nov K.ALQEFDLALR[166.11].G "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1184.6429 0.68 14574 18516 2 1184.645908 593.3287 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 4.37 3577.7 - 1.39E+06 - - - 2.5451 - 1.874 0.27 - 433.3 1 2 0 0.003 10 0 0 0 1.30E+07 1.93E+07 - - - 2.7874 1 230117_WJC_METTL3_WT_vs_EV_F02.18524.18524.2 6.98E-05 13/22 R.MGLAISLVATEK.E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 1231.6846 1.36 14580 18524 2 1231.687685 616.8496 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.75 3578.8 - 1.05E+06 - - - 2.4966 - 2.609 0.535 - 553.1 1 2 0 0.0031 12 0 0 0 5.19E+07 3.83E+07 - - - 5.5147 0.997 230117_WJC_METTL3_WT_vs_EV_F02.18527.18527.2 0.0782 14-Aug K.SIGDIFLK[136.11].Y "sp|Q9H8V3|ECT2_HUMAN,tr|H7C3G1|H7C3G1_HUMAN" 2 899.5208 1.01 14583 18527 2 899.52177 450.7677 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 5.55 3579.1 - 502637 - - - 1.1128 - 1.218 0.238 - 167.1 1 2 0 0.001 8 0 0 0 1.36E+07 1.35E+07 - - - 1.3933 0.9902 230117_WJC_METTL3_WT_vs_EV_F02.18534.18534.2 0.00328 16-Aug R.ILFLDPSGK.V sp|O95881|TXD12_HUMAN 1 988.5593 1.11 14588 18534 2 988.566159 495.2869 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3579.9 - 5.66E+07 - - - 6.905 - 1.69 0.407 - 176.5 1 2 0 0.0068 9 0 0 0 9.14E+08 8.26E+08 - - - 3.563 0.9913 230117_WJC_METTL3_WT_vs_EV_F02.18537.18537.2 0.0125 14-Aug R.LYLLQGIR.N "sp|Q9Y5A7|NUB1_HUMAN,tr|H3BM74|H3BM74_HUMAN,tr|H3BM14|H3BM14_HUMAN" 3 974.5913 1.64 14591 18537 2 974.597478 488.3029 NEDD8 ultimate buster 1 OS=Homo sapiens OX=9606 GN=NUB1 PE=1 SV=2 8.75 3580.1 - 2.23E+06 - - - 6.337 - 1.739 0.337 - 200.8 1 2 0 0.0062 8 0 0 0 9.60E+06 5.85E+06 - - - 3.1969 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.18538.18538.2 0.0422 18-Jul K.DLFGPALSVK[136.11].V tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN 1 1053.595 0.44 14592 18538 2 1053.598282 527.8048 Polyadenylate-binding protein OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=1 5.84 3580.2 - 1.80E+06 - - - 3.1179 - 1.437 0.253 - 113.1 1 2 0 0.0033 10 0 0 0 4.07E+06 9.34E+06 - - - 1.9206 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.18540.18540.2 0.0154 16-Sep R.ELGELIPLR.Q "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1038.6073 1.22 14594 18540 2 1038.612459 520.3109 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.53 3580.4 - 1.77E+06 - - - 4.9229 - 1.623 0.332 - 220.9 1 2 0 0.0051 9 0 0 0 1.41E+07 1.16E+07 - - - 2.8926 0.9969 230117_WJC_METTL3_WT_vs_EV_F02.18542.18542.2 0.0643 14-Jul K.GPFLLGIK.A sp|P21399|ACOHC_HUMAN 1 843.5218 4.64 14596 18542 2 843.524583 422.7682 Cytoplasmic aconitate hydratase OS=Homo sapiens OX=9606 GN=ACO1 PE=1 SV=3 8.75 3580.7 - 743143 - - - 3.2696 - 1.598 0.211 - 124.1 1 2 0 0.0028 8 0 0 0 3.19E+06 6.87E+05 - - - 2.0123 0.9789 230117_WJC_METTL3_WT_vs_EV_F02.18546.18546.2 0.871 12-Jun K.AFFDFGK.D sp|O15091|MRPP3_HUMAN 1 830.3963 0.73 14600 18546 2 830.398862 416.2054 Mitochondrial ribonuclease P catalytic subunit OS=Homo sapiens OX=9606 GN=PRORP PE=1 SV=2 5.88 3581.2 - 436229 - - - 3.0973 - 1.138 0.13 - 106.1 1 2 0 0.0026 7 0 0 0 3.75E+06 5.14E+06 - - - 0.41 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.18551.18551.2 0.00131 16-Sep R.ELGELIPLR[166.11].Q "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1048.6156 1.24 14603 18551 2 1048.621068 525.3151 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.53 3581.8 - 1.02E+06 - - - 5.1992 - 1.843 0.395 - 353.1 1 2 0 0.0055 9 0 0 0 1.38E+07 1.11E+07 - - - 3.7256 0.9324 230117_WJC_METTL3_WT_vs_EV_F02.18552.18552.2 0.0295 13/20 F.IGAIAIGDLVK[136.11].S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1076.6685 6.84 14604 18552 2 1076.67177 539.3415 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 3581.9 - 2.64E+06 - - - 3.0409 - 2.16 0.29 - 393.1 1 1 0 0.0033 11 0 0 0 1.39E+08 2.04E+07 - - - 3.2652 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.18554.18554.2 0.0148 14-Sep K.SYYLGLLR.S "sp|Q96LB3|IFT74_HUMAN,tr|E5RJK3|E5RJK3_HUMAN,tr|E5RGX6|E5RGX6_HUMAN,tr|A0A3B3IT46|A0A3B3IT46_HUMAN,tr|E5RIF0|E5RIF0_HUMAN,tr|E5RH29|E5RH29_HUMAN" 6 983.544 2.25 14606 18554 2 983.547526 492.7793 Intraflagellar transport protein 74 homolog OS=Homo sapiens OX=9606 GN=IFT74 PE=1 SV=1 8.31 3582.1 - 505425 - - - 3.5677 - 1.309 0.379 - 330.2 1 2 0 0.0035 8 0 0 0 1.29E+07 5.75E+06 - - - 2.6513 0.996 230117_WJC_METTL3_WT_vs_EV_F02.18555.18555.2 0.169 12-Jul R.NYLSIFR.K sp|P07384|CAN1_HUMAN 1 911.4865 2.71 14607 18555 2 911.487695 456.7505 Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1 8.75 3582.2 - 466215 - - - 1.3089 - 1.249 0.189 - 175.7 1 2 0 0.0012 7 0 0 0 3.28E+06 1.21E+06 - - - 1.1411 1 230117_WJC_METTL3_WT_vs_EV_F02.18557.18557.2 4.98E-05 18-Dec K.TLVQILTEPR.N sp|O76031|CLPX_HUMAN 1 1168.6816 2.13 14609 18557 2 1168.684622 585.3481 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3582.4 - 308884 - - - 2.6089 - 2.23 0.469 - 639.2 1 2 0 0.003 10 0 0 0 3.54E+06 1.66E+06 - - - 4.7427 0.9842 230117_WJC_METTL3_WT_vs_EV_F02.18559.18559.2 2.07 12-Jul K.DLLLPIK[136.11].T "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 3 818.5357 1.4 14611 18559 2 818.537274 410.2751 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 5.84 3582.7 - 198087 - - - 1.9339 - 1.442 0.002 - 206.3 1 2 0 0.0016 7 0 0 0 1.42E+07 1.02E+07 - - - 0.2151 0.9919 230117_WJC_METTL3_WT_vs_EV_F02.18561.18561.2 9.11 12-Jul K.EVILPIK.V sp|Q4G0P3|HYDIN_HUMAN 1 810.5215 1.4 14613 18561 2 810.522251 406.268 Hydrocephalus-inducing protein homolog OS=Homo sapiens OX=9606 GN=HYDIN PE=1 SV=3 6.1 3582.9 - 153852 - - - 0.9377 - 1.573 0.023 - 211.7 1 2 0 0.0008 7 0 0 0 1.42E+07 1.02E+07 - - - 0.6459 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18568.18568.2 0.000715 16-Sep K.LLQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1118.5748 13.47 14618 18568 2 1118.5774 560.2947 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3583.6 - 1.14E+06 - - - 2.3128 - 1.937 0.416 - 270.7 1 2 0 0.0026 9 0 0 0 2.79E+08 2.07E+07 - - - 4.0255 1 230117_WJC_METTL3_WT_vs_EV_F02.18569.18569.2 0.0125 18-Oct R.VLLMELEEAR[166.11].G sp|P12270|TPR_HUMAN 1 1211.6459 1.36 14619 18569 2 1211.648511 606.8302 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3583.7 - 988581 - - - 2.1302 - 2.377 0.524 - 416.8 1 2 0 0.0026 10 0 0 0 2.04E+07 1.51E+07 - - - 5.3273 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18571.18571.2 0.0149 12-Sep K.C[160.03]ALDFFR.Q sp|P51970|NDUA8_HUMAN 1 927.4273 1.36 14621 18571 2 927.428701 464.7209 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3583.9 - 560585 - - - 1.5397 - 1.699 0.341 - 317.6 1 2 0 0.0014 7 0 0 0 1.44E+07 1.06E+07 - - - 3.2386 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18575.18575.2 0.0153 12-Sep K.C[160.03]ALDFFR[166.11].Q sp|P51970|NDUA8_HUMAN 1 937.4355 1.36 14625 18575 2 937.437737 469.725 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3584.3 - 420360 - - - 2.3404 - 1.691 0.352 - 362.8 1 2 0 0.0022 7 0 0 0 1.44E+07 1.06E+07 - - - 3.3047 0.9898 230117_WJC_METTL3_WT_vs_EV_F02.18577.18577.2 0.0724 20-Aug R.LPPEFSPVIIK.E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1238.7275 0.42 14627 18577 2 1238.733285 620.371 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6 3584.5 - 380774 - - - 4.7016 - 1.588 0.206 - 102.3 1 2 0 0.0058 11 0 0 0 6.55E+06 1.57E+07 - - - 1.8118 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.18578.18578.2 0.302 16-Jul K.LQDPFSLYR.C sp|P21912|SDHB_HUMAN 1 1137.5819 3.97 14628 18578 2 1137.583126 569.7982 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.84 3584.6 - 322257 - - - 1.1138 - 1.707 0.205 - 91.1 4 2 0 0.0013 9 0 0 0 3.51E+07 8.84E+06 - - - 1.8328 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18580.18580.2 0.000288 24-Sep K.LFPDTPLALDANK[136.11].K sp|Q12906|ILF3_HUMAN 1 1421.7646 0.78 14630 18580 2 1421.769312 711.8896 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3584.9 - 280154 - - - 3.3276 - 1.809 0.459 - 214.1 1 2 0 0.0047 13 0 0 0 1.41E+07 1.80E+07 - - - 3.9511 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18582.18582.2 2.15E-06 24-Dec K.LFPDTPLALDANK.K sp|Q12906|ILF3_HUMAN 1 1413.7504 1.42 14632 18582 2 1413.752943 707.8825 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3585.1 - 249265 - - - 1.8122 - 2.02 0.501 - 250.6 1 2 0 0.0026 13 0 0 0 2.33E+06 1.64E+06 - - - 4.5451 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18583.18583.2 0.059 16-Oct K.LALFQAIGK.E "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 959.5804 1.1 14633 18583 2 959.582366 480.7975 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 8.75 3585.3 - 232775 - - - 2.0457 - 2.029 0.308 - 156.8 2 2 0 0.002 9 0 0 0 2.93E+06 2.66E+06 - - - 3.2278 0.9832 230117_WJC_METTL3_WT_vs_EV_F02.18585.18585.2 0.637 18-May R.LYYDGEWYIR.G "sp|Q5PSV4|BRM1L_HUMAN,tr|H0YHD0|H0YHD0_HUMAN" 2 1376.6401 1.18 14635 18585 2 1376.641992 689.3273 Breast cancer metastasis-suppressor 1-like protein OS=Homo sapiens OX=9606 GN=BRMS1L PE=1 SV=2 4.37 3585.5 - 161386 - - - 1.3729 - 1.076 0.118 - 78.3 1 2 0 0.0019 10 0 0 0 1.76E+06 1.49E+06 - - - 0.1164 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18587.18587.2 0.000445 16-Oct K.LLQDFFNGR.D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1108.5665 13.36 14636 18587 2 1108.569597 555.2905 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3585.8 - 4.84E+07 - - - 2.7549 - 2.06 0.448 - 389.9 1 2 0 0.0031 9 0 0 0 2.80E+08 2.10E+07 - - - 4.4398 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18589.18589.2 0.00128 18-Aug K.FLALYLHGAA.- "sp|Q9BZE1|RM37_HUMAN,tr|A6NHR2|A6NHR2_HUMAN" 2 1074.5862 - 14638 18589 2 1074.588686 538.3004 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 6.74 3586 - 5.65E+06 - - - 2.2986 - 1.664 0.365 - 155.2 1 2 0 0.0025 10 0 0 0 - - - - - 3.1575 1 230117_WJC_METTL3_WT_vs_EV_F02.18591.18591.2 7.90E-07 20/28 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 1.44 14640 18591 2 1458.759562 730.386 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3586.1 - 1.67E+06 - - - 1.443 - 3.812 0.584 - 1537.8 1 2 0 0.0021 15 0 0 0 1.85E+08 1.29E+08 - - - 6.6437 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18592.18592.2 0.000192 22-Oct K.YILAATLDNTLK[136.11].L sp|P61964|WDR5_HUMAN 1 1342.7588 1.53 14641 18592 2 1342.761061 672.3867 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 5.83 3586.2 - 1.44E+06 - - - 1.7077 - 2.132 0.43 - 225.6 1 2 0 0.0023 12 0 0 0 3.54E+07 2.32E+07 - - - 4.2082 1 230117_WJC_METTL3_WT_vs_EV_F02.18593.18593.2 2.26E-05 18/28 R.LPAAGVGDMVMATVK[136.11].K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1466.7717 1.44 14642 18593 2 1466.77401 734.3931 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3586.4 - 1.34E+06 - - - 1.6042 - 3.748 0.55 - 1110.8 1 2 0 0.0024 15 0 0 0 1.85E+08 1.29E+08 - - - 6.3508 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18595.18595.2 0.00693 14-Aug R.LLLEEIYR[166.11].G "sp|Q9Y2P8|RCL1_HUMAN,tr|Q5VZU2|Q5VZU2_HUMAN,tr|Q5VZU3|Q5VZU3_HUMAN" 3 1057.6047 0.76 14644 18595 2 1057.606981 529.8096 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 4.53 3586.6 - 1.06E+06 - - - 2.1407 - 1.856 0.321 - 239.6 1 2 0 0.0023 8 0 0 0 2.10E+07 2.79E+07 - - - 3.2763 1 230117_WJC_METTL3_WT_vs_EV_F02.18596.18596.2 3.29E-06 18-Dec K.LGMNLMNELK.Q "sp|Q16890|TPD53_HUMAN,tr|E9PNK6|E9PNK6_HUMAN,tr|E9PNQ9|E9PNQ9_HUMAN,tr|E9PPQ1|E9PPQ1_HUMAN,tr|J3KNE7|J3KNE7_HUMAN" 5 1161.5886 1.86 14645 18596 2 1161.591088 581.8016 Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1 6 3586.7 - 1.05E+06 - - - 2.141 - 2.547 0.503 - 357.9 1 2 0 0.0025 10 0 0 0 2.95E+06 1.58E+06 - - - 5.365 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18599.18599.2 0.0161 18-Oct K.TLVQILTEPR[166.11].N sp|O76031|CLPX_HUMAN 1 1178.6898 2.27 14648 18599 2 1178.692197 590.3522 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3587.1 - 660183 - - - 1.9971 - 2.045 0.423 - 380.2 1 2 0 0.0024 10 0 0 0 1.53E+07 6.75E+06 - - - 4.1614 0.9933 230117_WJC_METTL3_WT_vs_EV_F02.18602.18602.2 0.00302 12-Jul R.TIFSYFK.G sp|Q9UJV9|DDX41_HUMAN 1 904.4695 1.16 14651 18602 2 904.470908 453.242 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 8.26 3587.5 - 536872 - - - 1.6065 - 1.252 0.137 - 156.3 1 2 0 0.0015 7 0 0 0 2.49E+07 2.14E+07 - - - 0.7645 0.967 230117_WJC_METTL3_WT_vs_EV_F02.18603.18603.2 1.18 12-Jun K.LIPFLEK.L sp|Q05D32|CTSL2_HUMAN 1 858.5215 1.25 14652 18603 2 858.523201 430.268 CTD small phosphatase-like protein 2 OS=Homo sapiens OX=9606 GN=CTDSPL2 PE=1 SV=2 6 3587.6 - 392635 - - - 1.9918 - 1.02 0.086 - 96.9 1 2 0 0.0017 7 0 0 0 2.57E+06 2.05E+06 - - - -0.2616 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18611.18611.2 0.0373 18-Jul R.LGLLGLPAPK[136.11].N sp|Q99459|CDC5L_HUMAN 1 985.6416 1.15 14659 18611 2 985.643325 493.8281 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3588.4 - 2.36E+06 - - - 1.7978 - 1.764 0.318 - 94.6 1 2 0 0.0018 10 0 0 0 9.74E+07 8.50E+07 - - - 2.9735 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.18612.18612.2 0.0172 18-Nov R.LGLLGLPAPK.N sp|Q99459|CDC5L_HUMAN 1 977.6274 1.13 14660 18612 2 977.628404 489.821 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3588.5 - 2.14E+06 - - - 1.0751 - 2.269 0.116 - 293.1 1 2 0 0.0011 10 0 0 0 9.76E+07 8.61E+07 - - - 2.1845 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.18614.18614.2 0.175 14-Jul R.LLLEEIYR.G "sp|Q9Y2P8|RCL1_HUMAN,tr|Q5VZU2|Q5VZU2_HUMAN,tr|Q5VZU3|Q5VZU3_HUMAN" 3 1047.5964 0.76 14662 18614 2 1047.597775 524.8055 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 4.53 3588.6 - 984041 - - - 1.2677 - 1.653 0.266 - 176 1 2 0 0.0013 8 0 0 0 2.10E+07 2.79E+07 - - - 2.5211 0.9343 230117_WJC_METTL3_WT_vs_EV_F02.18615.18615.2 0.0955 18-Aug K.MIIENFEALK.S "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1206.6318 1.37 14663 18615 2 1206.638605 604.3232 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 4.53 3588.6 - 930799 - - - 5.6015 - 1.356 0.119 - 148.1 1 2 0 0.0068 10 0 0 0 1.41E+07 1.03E+07 - - - 0.7679 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.18616.18616.3 2.66E-06 14/56 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 1.49 14664 18616 3 1458.758673 487.2598 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3588.7 - 885804 - - - 0.8336 - 2.469 0.409 - 299.2 1 2 0 0.0012 15 0 0 0 5.67E+07 3.81E+07 - - - 5.458 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18617.18617.2 0.0015 20-Nov R.LYEAYLPETFR.R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1400.6976 2.4 14665 18617 2 1400.700978 701.3561 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3588.8 - 756846 - - - 2.3995 - 2.25 0.37 - 428.8 1 2 0 0.0034 11 0 0 0 4.98E+07 2.07E+07 - - - 3.9665 1 230117_WJC_METTL3_WT_vs_EV_F02.18619.18619.2 2.64E-05 20-Sep R.IFVFEPPPGVK.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 1228.6856 2.12 14667 18619 2 1228.68653 615.3501 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3588.9 - 433107 - - - 0.7602 - 2.074 0.499 - 260 1 2 0 0.0009 11 0 0 0 3.90E+06 1.84E+06 - - - 4.6997 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.18627.18627.2 0.000104 20-Oct R.IFVFEPPPGVK[136.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 1236.6998 2.12 14674 18627 2 1236.704445 619.3572 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3589.8 - 323840 - - - 3.7592 - 1.98 0.461 - 303.8 1 2 0 0.0046 11 0 0 0 3.90E+06 1.84E+06 - - - 4.2924 1 230117_WJC_METTL3_WT_vs_EV_F02.18630.18630.2 1.74E-06 15/30 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 17.16 14676 18630 2 1686.898254 844.4543 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3590.1 - 6.76E+06 - - - 2.4714 - 3.024 0.526 - 604.5 1 2 0 0.0042 16 0 0 0 7.66E+07 4.47E+06 - - - 5.6453 0.9671 230117_WJC_METTL3_WT_vs_EV_F02.18631.18631.2 1 12-Mar R.LFLEFER.K "sp|O43663|PRC1_HUMAN,sp|Q96I25|SPF45_HUMAN,tr|H0YL53|H0YL53_HUMAN" 3 952.5018 2.3 14677 18631 2 952.504302 477.2582 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 3590.2 - 2.87E+06 - - - 2.6079 - 1.068 0.175 - 24.8 25 2 0 0.0025 7 0 0 0 1.77E+07 7.70E+06 - - - -0.0832 1 230117_WJC_METTL3_WT_vs_EV_F02.18632.18632.2 0.000423 20-Dec K.LALDMEIATYR.K "sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|Q14CN4|K2C72_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 4 1294.6591 29.94 14678 18632 2 1294.660062 648.3368 "Keratin, type II cytoskeletal 74 OS=Homo sapiens OX=9606 GN=KRT74 PE=1 SV=2" 4.37 3590.3 - 2.17E+06 - - - 0.7253 - 2.675 0.481 - 710.8 1 2 0 0.0009 11 0 0 0 7.67E+06 2.56E+05 - - - 5.2552 0.9951 230117_WJC_METTL3_WT_vs_EV_F02.18633.18633.2 0.00809 14-Aug K.YLELLGYR[166.11].K "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 7 1035.5629 1.68 14679 18633 2 1035.566405 518.7887 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6 3590.4 - 1.36E+06 - - - 3.431 - 1.713 0.141 - 187.1 1 2 0 0.0036 8 0 0 0 1.17E+07 6.98E+06 - - - 1.7046 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.18635.18635.2 0.0116 12-Jun R.VWSDFLR.V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 921.4709 2.01 14681 18635 2 921.472329 461.7427 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.81 3590.6 - 902388 - - - 1.6029 - 1.358 0.285 - 164 1 2 0 0.0015 7 0 0 0 9.04E+06 4.50E+06 - - - 2.1152 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.18637.18637.2 0.00112 14-Jul R.WVVPVLPK[136.11].G "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 944.5939 1.95 14683 18637 2 944.597317 473.3042 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3590.8 - 679353 - - - 3.645 - 1.466 0.411 - 101.8 1 2 0 0.0034 8 0 0 0 6.69E+06 3.43E+06 - - - 3.2293 1 230117_WJC_METTL3_WT_vs_EV_F02.18642.18642.2 7.93E-08 13/30 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 16.79 14688 18642 2 1696.902609 849.4585 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3591.5 - 484012 - - - 0.1497 - 3.007 0.607 - 421.3 1 2 0 0.0003 16 0 0 0 7.50E+07 4.47E+06 - - - 6.2309 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18646.18646.2 0.0262 20-Sep R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 6.06 14691 18646 2 1068.656854 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 3592 - 464466 - - - 2.3937 - 2.128 0.291 - 190.4 1 2 0 0.0026 11 0 0 0 1.70E+08 2.80E+07 - - - 3.2325 1 230117_WJC_METTL3_WT_vs_EV_F02.18648.18648.3 5.81E-11 25/60 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 19.25 14692 18648 3 1686.897771 563.3053 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3592.2 - 6.23E+06 - - - 2.1851 - 3.987 0.617 - 828.1 1 2 0 0.0037 16 0 0 0 4.70E+07 2.44E+06 - - - 8.9666 1 230117_WJC_METTL3_WT_vs_EV_F02.18649.18649.2 2.90E-05 13/20 R.LYEAYLPETFR[166.11].R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1410.7059 2.4 14693 18649 2 1410.709484 706.3602 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3592.3 - 2.50E+06 - - - 2.5498 - 2.601 0.509 - 688.5 1 2 0 0.0036 11 0 0 0 4.98E+07 2.07E+07 - - - 5.3853 1 230117_WJC_METTL3_WT_vs_EV_F02.18652.18652.2 3.79E-05 16/22 K.FGEAIGMGFPVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1259.6464 0.98 14696 18652 2 1259.651898 630.8305 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3592.7 - 1.81E+06 - - - 4.3806 - 2.821 0.513 - 935.2 1 2 0 0.0055 12 0 0 0 1.90E+08 1.95E+08 - - - 5.557 1 230117_WJC_METTL3_WT_vs_EV_F02.18656.18656.2 0.000179 18-Nov R.EDIVVPVYLR.E "sp|P51784|UBP11_HUMAN,tr|G5E9A6|G5E9A6_HUMAN" 2 1201.6707 12.91 14700 18656 2 1201.677704 601.8426 Ubiquitin carboxyl-terminal hydrolase 11 OS=Homo sapiens OX=9606 GN=USP11 PE=1 SV=3 4.37 3593.2 - 1.06E+06 - - - 5.8502 - 2.462 0.497 - 519 1 2 0 0.007 10 0 0 0 2.30E+07 1.78E+06 - - - 5.2245 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.18657.18657.2 0.000682 13/22 K.GGIVGMTLPIAR.D "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 1183.6747 1.06 14701 18657 2 1183.68064 592.8446 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 9.75 3593.3 - 888142 - - - 5.0064 - 2.204 0.402 - 500 1 2 0 0.0059 12 0 0 0 1.41E+07 1.33E+07 - - - 4.0877 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18658.18658.3 7.20E-07 19/60 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 18.96 14702 18658 3 1696.910758 566.6414 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3593.5 - 489823 - - - 4.952 - 3.074 0.458 - 342.7 1 2 0 0.0084 16 0 0 0 4.63E+07 2.44E+06 - - - 6.5253 1 230117_WJC_METTL3_WT_vs_EV_F02.18660.18660.2 1.30E-06 20-Nov K.VIAEDEVLWYR.L "sp|Q8N3Y1|FBXW8_HUMAN,tr|A0A499FIY5|A0A499FIY5_HUMAN" 2 1391.7085 0.58 14704 18660 2 1391.714718 696.8615 F-box\WD repeat-containing protein 8 OS=Homo sapiens OX=9606 GN=FBXW8 PE=1 SV=2 4.14 3593.7 - 477332 - - - 4.4564 - 2.457 0.556 - 376.4 1 2 0 0.0062 11 0 0 0 2.73E+06 4.74E+06 - - - 5.5775 1 230117_WJC_METTL3_WT_vs_EV_F02.18662.18662.2 0.00152 13/18 K.TNVALMC[160.03]MLR[166.11].E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1217.5958 1.3 14706 18662 2 1217.601051 609.8052 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 7.91 3594 - 406064 - - - 4.2921 - 2.342 0.471 - 712.5 1 2 0 0.0052 10 0 0 0 6.34E+06 4.87E+06 - - - 4.8936 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.18670.18670.2 0.00271 14-Aug K.YLELLGYR.K "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 7 1025.5546 1.68 14713 18670 2 1025.559429 513.7846 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6 3594.9 - 3.08E+06 - - - 4.7262 - 1.682 0.406 - 247.5 1 2 0 0.0048 8 0 0 0 1.17E+07 6.98E+06 - - - 3.6064 1 230117_WJC_METTL3_WT_vs_EV_F02.18672.18672.2 8.34E-08 22-Dec K.FGEAIGMGFPVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1251.6322 0.98 14715 18672 2 1251.633352 626.8234 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3595 - 6.54E+06 - - - 0.9364 - 2.269 0.541 - 471.4 1 2 0 0.0012 12 0 0 0 1.90E+08 1.95E+08 - - - 5.1923 0.9745 230117_WJC_METTL3_WT_vs_EV_F02.18673.18673.2 2.22 16-May R.TTLLPGLLK.T sp|Q9NSD9|SYFB_HUMAN 1 954.6114 2.87 14716 18673 2 954.61215 478.313 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 8.41 3595 - 5.87E+06 - - - 0.8192 - 0.952 0.133 - 69.4 1 2 0 0.0008 9 0 0 0 1.64E+07 5.70E+06 - - - -0.1192 0.999 230117_WJC_METTL3_WT_vs_EV_F02.18675.18675.2 0.095 14-Jul R.EALAFIIR[166.11].S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 941.5574 0.9 14718 18675 2 941.557976 471.786 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3595.1 - 2.87E+06 - - - 0.6415 - 1.661 0.258 - 206.4 1 2 0 0.0006 8 0 0 0 8.86E+06 9.87E+06 - - - 2.4768 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18676.18676.2 0.0137 14-Jul R.EALAFIIR.S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 931.5491 1.3 14719 18676 2 931.549724 466.7818 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3595.1 - 2.65E+06 - - - 0.6677 - 1.694 0.3 - 201.2 1 2 0 0.0006 8 0 0 0 3.20E+07 2.47E+07 - - - 2.8463 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.18677.18677.2 0.0445 18-Aug R.VLGLGLGC[160.03]LR[166.11].L "sp|Q9BRJ7|TIRR_HUMAN,tr|W4VSQ8|W4VSQ8_HUMAN,tr|K7EIN2|K7EIN2_HUMAN,tr|K7ENA3|K7ENA3_HUMAN" 4 1066.6197 4.52 14720 18677 2 1066.621339 534.3171 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3595.2 - 2.52E+06 - - - 1.5788 - 1.793 0.272 - 190.9 1 2 0 0.0017 10 0 0 0 2.02E+07 4.46E+06 - - - 2.6793 1 230117_WJC_METTL3_WT_vs_EV_F02.18678.18678.2 6.19E-07 13/22 R.LLYMAIDGVAPR[166.11].A sp|Q9H0D6|XRN2_HUMAN 1 1327.7198 1.04 14721 18678 2 1327.724855 664.8672 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3595.2 - 2.46E+06 - - - 3.8351 - 2.389 0.557 - 662.1 1 2 0 0.0051 12 0 0 0 2.34E+07 2.24E+07 - - - 5.4448 1 230117_WJC_METTL3_WT_vs_EV_F02.18679.18679.2 9.58E-07 22-Nov R.LLYMAIDGVAPR.A sp|Q9H0D6|XRN2_HUMAN 1 1317.7115 1.04 14722 18679 2 1317.712587 659.863 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3595.3 - 2.45E+06 - - - 0.8302 - 2.43 0.495 - 601.8 1 2 0 0.0011 12 0 0 0 2.34E+07 2.24E+07 - - - 5.0329 0.9032 230117_WJC_METTL3_WT_vs_EV_F02.18680.18680.2 4.01 16-Jun R.TTLLPGLLK[136.11].T sp|Q9NSD9|SYFB_HUMAN 1 962.6256 2.86 14723 18680 2 962.625825 482.3201 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 8.41 3595.3 - 2.24E+06 - - - 0.267 - 0.92 0.044 - 91.2 1 2 0 0.0003 9 0 0 0 1.63E+07 5.70E+06 - - - -0.8753 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18681.18681.2 0.00377 18-Oct K.TNVALMC[160.03]MLR.E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1207.5876 1.3 14724 18681 2 1207.589087 604.8011 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 7.91 3595.4 - 2.23E+06 - - - 1.2686 - 2.121 0.426 - 434.9 1 2 0 0.0015 10 0 0 0 6.34E+06 4.87E+06 - - - 4.2857 0.9705 230117_WJC_METTL3_WT_vs_EV_F02.18683.18683.2 0.0972 20-Jul R.SEGVVAVLLTK.K "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1114.6598 2.13 14726 18683 2 1114.665447 558.3372 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.72 3595.5 - 2.96E+06 - - - 5.0885 - 1.355 0.172 - 142.6 1 2 0 0.0057 11 0 0 0 1.19E+07 5.58E+06 - - - 1.1315 0.9949 230117_WJC_METTL3_WT_vs_EV_F02.18691.18691.2 0.982 12-Aug R.LQFLFAK.D "sp|Q7Z3K3|POGZ_HUMAN,tr|H0YCT3|H0YCT3_HUMAN" 2 865.5062 0.8 14733 18691 2 865.506232 433.7604 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 8.75 3596.2 - 858398 - - - 0.0659 - 1.291 0.187 - 192.6 1 2 0 0.0001 7 0 0 0 3.07E+06 3.84E+06 - - - 1.2315 0.9512 230117_WJC_METTL3_WT_vs_EV_F02.18692.18692.2 0.00055 18-Nov R.VLGLGLGC[160.03]LR.L "sp|Q9BRJ7|TIRR_HUMAN,tr|W4VSQ8|W4VSQ8_HUMAN,tr|K7EIN2|K7EIN2_HUMAN,tr|K7ENA3|K7ENA3_HUMAN" 4 1056.6114 4.69 14734 18692 2 1056.620757 529.313 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3596.3 - 2.12E+06 - - - 8.8699 - 2.085 0.184 - 287.8 1 2 0 0.0094 10 0 0 0 2.09E+07 4.46E+06 - - - 2.448 0.9948 230117_WJC_METTL3_WT_vs_EV_F02.18695.18695.2 0.144 14-Jul R.WVVPVLPK.G "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 936.5797 1.89 14737 18695 2 936.582797 469.2971 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3596.6 - 986841 - - - 3.3345 - 1.432 0.199 - 167.2 1 2 0 0.0031 8 0 0 0 6.48E+06 3.43E+06 - - - 1.5928 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.18697.18697.2 0.000113 16-Aug R.LVLDWDSVR.A "sp|Q68EM7|RHG17_HUMAN,tr|C9IZD3|C9IZD3_HUMAN,tr|I3L4P6|I3L4P6_HUMAN" 3 1101.5819 2.34 14739 18697 2 1101.585719 551.7982 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4.21 3596.9 - 842578 - - - 3.5041 - 1.784 0.368 - 198.8 1 2 0 0.0039 9 0 0 0 2.20E+07 9.42E+06 - - - 3.4325 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.18698.18698.2 0.000634 20-Sep R.VLPSITTEILK.S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1212.7329 1.48 14740 18698 2 1212.736413 607.3737 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 3597 - 824682 - - - 2.8638 - 1.876 0.274 - 218.3 1 2 0 0.0035 11 0 0 0 3.33E+08 2.25E+08 - - - 2.7657 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18700.18700.2 0.000177 13/20 R.VLPSITTEILK[136.11].S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1220.7471 1.48 14742 18700 2 1220.75058 611.3808 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 3597.2 - 599000 - - - 2.8179 - 1.954 0.414 - 536.5 1 2 0 0.0034 11 0 0 0 3.33E+08 2.25E+08 - - - 3.9099 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.18701.18701.2 0.00439 12-Jul R.LQFLFAK[136.11].D "sp|Q7Z3K3|POGZ_HUMAN,tr|H0YCT3|H0YCT3_HUMAN" 2 873.5204 1.1 14743 18701 2 873.524074 437.7675 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 8.75 3597.4 - 593244 - - - 4.2346 - 1.472 0.377 - 133.1 1 2 0 0.0037 7 0 0 0 2.98E+06 2.71E+06 - - - 3.0494 1 230117_WJC_METTL3_WT_vs_EV_F02.18705.18705.2 5.39E-06 20-Oct R.VYPQAVYFPIR.T "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1351.7289 1.67 14747 18705 2 1351.733497 676.8717 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.56 3597.9 - 364039 - - - 3.4319 - 2.219 0.469 - 392.6 1 2 0 0.0046 11 0 0 0 1.50E+06 9.01E+05 - - - 4.6598 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18708.18708.2 0.000142 22-Oct R.VIQEGLEGLVLK.D sp|P49916|DNLI3_HUMAN 1 1296.7653 -1 14750 18708 2 1296.76984 649.3899 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 4.53 3598.3 - 331136 - - - 3.4987 - 1.963 0.473 - 239.6 1 2 0 0.0045 12 0 0 0 0.00E+00 0.00E+00 - - - 4.3078 1 230117_WJC_METTL3_WT_vs_EV_F02.18711.18711.2 4.04E-07 13/26 K.IVIPNEESVVIYYK[136.11].L sp|P42285|MTREX_HUMAN 1 1672.9167 -1 14752 18711 2 1672.916533 837.4656 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.53 3598.6 - 167195 - - - -0.1148 - 2.379 0.623 - 360.8 1 2 0 -0.0002 14 0 0 0 0.00E+00 0.00E+00 - - - 5.8173 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.18713.18713.2 0.178 20-Sep K.LVFLGLDNAGK.T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1145.6445 1.63 14754 18713 2 1145.6479 573.8295 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3598.8 - 1.20E+07 - - - 3.0035 - 1.747 0.373 - 219.6 1 2 0 0.0034 11 0 0 0 3.18E+08 1.95E+08 - - - 3.3041 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18714.18714.2 4.78E-05 20-Oct K.LVFLGLDNAGK[136.11].T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1153.6587 1.63 14755 18714 2 1153.661881 577.8366 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3598.8 - 8.48E+06 - - - 2.7929 - 1.994 0.412 - 272.2 1 2 0 0.0032 11 0 0 0 3.18E+08 1.95E+08 - - - 3.95 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18716.18716.2 0.0032 18-Oct R.YLNWIGVPTK[136.11].V "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|A0A1W2PNV9|A0A1W2PNV9_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN,tr|F6XNB3|F6XNB3_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 9 1197.6637 0.34 14757 18716 2 1197.66715 599.8391 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.59 3599 - 1.14E+06 - - - 2.843 - 1.94 0.362 - 345.6 1 2 0 0.0034 10 0 0 0 4.01E+06 1.19E+07 - - - 3.5634 0.999 230117_WJC_METTL3_WT_vs_EV_F02.18718.18718.2 0.0998 16-Sep R.ALLLSTYIK.F "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|A0A0G2JS82|A0A0G2JS82_HUMAN,tr|A0A0G2JQM1|A0A0G2JQM1_HUMAN" 4 1020.6219 1.23 14759 18718 2 1020.623277 511.3182 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 8.63 3599.2 - 680871 - - - 1.3168 - 1.95 0.216 - 229.5 2 2 0 0.0013 9 0 0 0 5.09E+06 4.15E+06 - - - 2.4335 0.999 230117_WJC_METTL3_WT_vs_EV_F02.18719.18719.2 0.215 16-Sep R.ALLLSTYIK[136.11].F "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|A0A0G2JS82|A0A0G2JS82_HUMAN,tr|A0A0G2JQM1|A0A0G2JQM1_HUMAN" 4 1028.6361 1.23 14760 18719 2 1028.638847 515.3253 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 8.63 3599.3 - 643538 - - - 2.6384 - 1.875 0.274 - 241.4 1 2 0 0.0027 9 0 0 0 5.09E+06 4.15E+06 - - - 2.8825 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18721.18721.2 0.0303 16-Oct R.LNILDTLSK.F "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1015.5914 1.49 14762 18721 2 1015.593943 508.803 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 5.84 3599.6 - 587056 - - - 2.5424 - 1.934 0.303 - 268.9 1 2 0 0.0026 9 0 0 0 2.33E+06 1.56E+06 - - - 3.1864 0.9445 230117_WJC_METTL3_WT_vs_EV_F02.18723.18723.2 3.37 20-Jul R.FYSLLDPSYAK.N sp|P46977|STT3A_HUMAN 1 1302.6496 2.46 14764 18723 2 1302.652914 652.3321 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 5.83 3599.8 - 205962 - - - 2.541 - 1.094 0.036 - 94.1 1 2 0 0.0033 11 0 0 0 2.14E+06 8.70E+05 - - - -0.4511 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18724.18724.2 0.0538 16-Aug R.VLAINILGR.F sp|O43747|AP1G1_HUMAN 1 967.6179 0.54 14765 18724 2 967.619388 484.8162 AP-1 complex subunit gamma-1 OS=Homo sapiens OX=9606 GN=AP1G1 PE=1 SV=5 9.72 3599.9 - 170882 - - - 1.5884 - 1.806 0.268 - 211.2 1 2 0 0.0015 9 0 0 0 4.81E+06 8.94E+06 - - - 2.7301 0.9609 230117_WJC_METTL3_WT_vs_EV_F02.18726.18726.2 13.9 12-May K.ELLALLK[136.11].C "sp|Q92560|BAP1_HUMAN,sp|Q8NA66|CNBD1_HUMAN,sp|Q8NGS7|O13C8_HUMAN,sp|Q8NGV5|O13D1_HUMAN,sp|Q8NGS4|O13F1_HUMAN,tr|A0A087WTB2|A0A087WTB2_HUMAN,tr|F8W6N3|F8W6N3_HUMAN,tr|H0Y8E8|H0Y8E8_HUMAN,tr|H0YC59|H0YC59_HUMAN,tr|A0A286YF94|A0A286YF94_HUMAN" 10 806.5357 0.16 14767 18726 2 806.537862 404.2751 Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Homo sapiens OX=9606 GN=BAP1 PE=1 SV=2 6.1 3600.2 - 120844 - - - 2.6918 - 1.234 0.017 - 80.6 1 2 0 0.0022 7 0 0 0 5.32E+06 3.40E+07 - - - -0.1679 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.18730.18730.2 0.0403 14-Jul R.ILFFNTPK.K "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 978.5539 1.32 14769 18730 2 978.556286 490.2842 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 8.75 3600.8 - 2.76E+06 - - - 2.4853 - 1.46 0.355 - 136 1 2 0 0.0024 8 0 0 0 8.21E+07 6.20E+07 - - - 2.8036 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.18731.18731.2 0.18 12-Jul K.LIFYDLR.G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 938.5226 1.15 14770 18731 2 938.525 470.2686 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3600.8 - 1.67E+06 - - - 2.6073 - 1.44 0.344 - 192.9 1 2 0 0.0024 7 0 0 0 5.29E+07 4.60E+07 - - - 2.7364 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18732.18732.2 0.0111 14-Aug R.ILFFNTPK[136.11].K "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 986.5681 1.31 14771 18732 2 986.569462 494.2913 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 8.75 3600.9 - 1.68E+06 - - - 1.4272 - 1.675 0.37 - 174.7 1 2 0 0.0014 8 0 0 0 8.21E+07 6.26E+07 - - - 3.329 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.18733.18733.2 0.399 12-Jun R.VLVWDLR[166.11].N "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 909.5312 1.09 14772 18733 2 909.531945 455.7729 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.81 3600.9 - 1.53E+06 - - - 0.8653 - 1.454 0.256 - 205.1 1 2 0 0.0008 7 0 0 0 6.70E+07 6.14E+07 - - - 2.1176 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18734.18734.2 0.000582 16-Sep R.MADFWLTEK.D sp|Q9NRX2|RM17_HUMAN 1 1139.5321 1.3 14773 18734 2 1139.534381 570.7733 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 4.37 3601 - 1.05E+06 - - - 1.9736 - 1.876 0.484 - 226.9 1 2 0 0.0022 9 0 0 0 8.58E+06 6.58E+06 - - - 4.4353 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18735.18735.2 0.000117 14-Sep R.QAFYFALR.D "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1014.5287 1.51 14774 18735 2 1014.531051 508.2716 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.75 3601 - 918321 - - - 2.3163 - 1.667 0.44 - 281.4 1 2 0 0.0024 8 0 0 0 8.12E+06 5.38E+06 - - - 3.8313 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.18736.18736.2 0.00222 18-Jul R.FPPVVFYTPK.E "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1193.6485 0.72 14775 18736 2 1193.649978 597.8315 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3601.1 - 776712 - - - 1.2533 - 1.515 0.31 - 169.3 1 2 0 0.0015 10 0 0 0 1.25E+07 1.73E+07 - - - 2.4897 0.999 230117_WJC_METTL3_WT_vs_EV_F02.18737.18737.2 0.0268 16-Sep R.GDLLFLTNR.V "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 1047.5713 1.23 14776 18737 2 1047.573092 524.7929 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.84 3601.1 - 765442 - - - 1.7154 - 1.621 0.263 - 217.6 1 2 0 0.0018 9 0 0 0 8.06E+06 6.57E+06 - - - 2.3804 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18738.18738.2 0.0415 18-Aug R.LWTPPEDYRL.- "sp|Q9BYD1|RM13_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 2 1288.6452 1.55 14777 18738 2 1288.64821 645.3299 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.37 3601.2 - 691496 - - - 2.3451 - 1.756 0.351 - 303.3 1 2 0 0.003 10 0 0 0 1.72E+07 1.11E+07 - - - 3.2041 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18739.18739.2 9.51E-05 14-Sep R.QAFYFALR[166.11].D "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1024.537 1.73 14778 18739 2 1024.538544 513.2758 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.75 3601.2 - 614108 - - - 1.5353 - 1.748 0.409 - 343.1 1 2 0 0.0016 8 0 0 0 1.06E+07 6.11E+06 - - - 3.7457 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.18740.18740.2 0.0219 18-Sep K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.21 14779 18740 2 1086.646976 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3601.3 - 565202 - - - 2.9863 - 1.789 0.265 - 225.5 1 2 0 0.0032 10 0 0 0 4.85E+08 4.01E+08 - - - 2.6209 1 230117_WJC_METTL3_WT_vs_EV_F02.18742.18742.2 5.49E-05 15/26 R.ALMGSPQLVAAVVR.T "sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9J826|C9J826_HUMAN" 5 1410.8017 999 14781 18742 2 1410.805691 706.4081 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 9.79 3601.4 - 464434 - - - 2.8253 - 2.76 0.498 - 674.1 1 2 0 0.004 14 0 0 0 1.48E+07 0.00E+00 - - - 5.2656 0.999 230117_WJC_METTL3_WT_vs_EV_F02.18743.18743.2 0.00485 14-Jun R.ELSPLFLR.F sp|O75691|UTP20_HUMAN 1 973.5597 1.07 14782 18743 2 973.560345 487.7871 Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3 6.1 3601.5 - 449468 - - - 0.6964 - 1.52 0.298 - 165.5 1 2 0 0.0007 8 0 0 0 7.30E+06 6.80E+06 - - - 2.5046 0.9953 230117_WJC_METTL3_WT_vs_EV_F02.18744.18744.2 1.36 14-Sep K.C[160.03]QLLFALK[136.11].V "sp|Q9BRJ7|TIRR_HUMAN,tr|K7EIN2|K7EIN2_HUMAN" 2 999.5667 0.97 14783 18744 2 999.566886 500.7906 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3601.6 - 425650 - - - 0.2121 - 1.369 0.17 - 172.6 1 2 0 0.0002 8 0 0 0 1.03E+07 1.07E+07 - - - 1.2438 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18751.18751.2 1.23 16-Sep R.FEALNLSFK.N "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 12 1067.5651 2.75 14788 18751 2 1067.567411 534.7898 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 6 3602.4 - 8.78E+06 - - - 2.1207 - 1.937 0.318 - 204.7 1 2 0 0.0023 9 0 0 0 1.15E+08 4.17E+07 - - - 3.3018 0.999 230117_WJC_METTL3_WT_vs_EV_F02.18752.18752.2 0.00905 14-Jul R.FLIQNVLR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1011.6105 1.44 14789 18752 2 1011.612284 506.8125 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.75 3602.5 - 4.29E+06 - - - 1.7922 - 1.674 0.248 - 204 1 2 0 0.0018 8 0 0 0 1.58E+08 1.10E+08 - - - 2.426 0.9261 230117_WJC_METTL3_WT_vs_EV_F02.18753.18753.2 7.41 12-Jun R.LTIAILR.H "sp|Q5XPI4|RN123_HUMAN,sp|Q96B70|LENG9_HUMAN,tr|C9J266|C9J266_HUMAN,tr|A0A087WVD1|A0A087WVD1_HUMAN,tr|C9JS59|C9JS59_HUMAN" 5 798.5327 2.27 14790 18753 2 798.533575 400.2736 E3 ubiquitin-protein ligase RNF123 OS=Homo sapiens OX=9606 GN=RNF123 PE=1 SV=1 9.75 3602.5 - 1.87E+06 - - - 1.0657 - 1.033 0.002 - 160.9 1 2 0 0.0009 7 0 0 0 8.28E+07 3.64E+07 - - - -0.8416 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18757.18757.2 0.000441 20-Aug K.YLLDSC[160.03]APLLR.Y sp|Q92616|GCN1_HUMAN 1 1319.6908 1.16 14794 18757 2 1319.691401 660.8527 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.83 3602.7 - 1.13E+06 - - - 0.4872 - 1.8 0.403 - 197.8 1 2 0 0.0006 11 0 0 0 8.84E+06 7.65E+06 - - - 3.6075 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18758.18758.2 1.10E-05 20-Oct K.YLLDSC[160.03]APLLR[166.11].Y sp|Q92616|GCN1_HUMAN 1 1329.699 1.16 14795 18758 2 1329.700172 665.8568 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.83 3602.8 - 1.03E+06 - - - 0.8603 - 1.912 0.505 - 355.6 1 2 0 0.0011 11 0 0 0 8.84E+06 7.65E+06 - - - 4.524 0.9928 230117_WJC_METTL3_WT_vs_EV_F02.18760.18760.2 0.0973 18-Jun R.LWTPPEDYR[166.11]L.- "sp|Q9BYD1|RM13_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 2 1298.6535 1.56 14797 18760 2 1298.650999 650.334 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.37 3602.9 - 924700 - - - -1.8935 - 1.502 0.244 - 159.9 1 2 0 -0.0025 10 0 0 0 1.74E+07 1.11E+07 - - - 1.9779 0.9904 230117_WJC_METTL3_WT_vs_EV_F02.18763.18763.2 2.9 12-Jun R.TLIGFLR.S "sp|O15116|LSM1_HUMAN,tr|E5RH18|E5RH18_HUMAN,tr|E5RJ47|E5RJ47_HUMAN" 3 818.5014 1.56 14800 18763 2 818.502463 410.258 U6 snRNA-associated Sm-like protein LSm1 OS=Homo sapiens OX=9606 GN=LSM1 PE=1 SV=1 9.41 3603.1 - 809985 - - - 1.2694 - 1.237 0.106 - 145.6 1 2 0 0.001 7 0 0 0 1.85E+07 1.19E+07 - - - 0.4975 0.9831 230117_WJC_METTL3_WT_vs_EV_F02.18764.18764.2 0.236 16-Jul K.ALLSALELK[136.11].K sp|P49454|CENPF_HUMAN 1 964.6048 1.13 14801 18764 2 964.60616 483.3097 Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3 6.05 3603.2 - 802098 - - - 1.3757 - 1.342 0.077 - 88.1 6 2 0 0.0013 9 0 0 0 4.33E+06 3.84E+06 - - - 0.1127 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18765.18765.2 0.000871 24-Dec R.LIEETISIAMATK[136.11].E "sp|O95249|GOSR1_HUMAN,tr|E9PCW1|E9PCW1_HUMAN,tr|G5E9T8|G5E9T8_HUMAN" 3 1426.7833 0.67 14802 18765 2 1426.78672 714.3989 Golgi SNAP receptor complex member 1 OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 4.53 3603.3 - 704537 - - - 2.4194 - 2.052 0.45 - 350.6 1 2 0 0.0035 13 0 0 0 3.70E+06 5.56E+06 - - - 4.2085 0.9928 230117_WJC_METTL3_WT_vs_EV_F02.18766.18766.2 0.426 16-May K.ALLSALELK.K sp|P49454|CENPF_HUMAN 1 956.5906 1.07 14803 18766 2 956.591098 479.3026 Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3 6.05 3603.4 - 687839 - - - 0.4861 - 1.096 0.224 - 50.7 2 2 0 0.0005 9 0 0 0 4.11E+06 3.84E+06 - - - 0.826 0.997 230117_WJC_METTL3_WT_vs_EV_F02.18767.18767.2 0.00428 18-Nov R.IPDEIIDMVK.E "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1171.6159 2.22 14804 18767 2 1171.612868 586.8152 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 4.03 3603.5 - 569658 - - - -2.5554 - 1.906 0.364 - 328.8 1 2 0 -0.003 10 0 0 0 5.07E+07 2.28E+07 - - - 3.529 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.18769.18769.2 0.0293 12-May R.EFIEMWR[166.11].L "sp|Q7L0Y3|TM10C_HUMAN,tr|C9JVB6|C9JVB6_HUMAN" 2 1019.4774 0.88 14806 18769 2 1019.477175 510.746 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 4.53 3603.6 - 513070 - - - -0.2285 - 1.306 0.288 - 110.1 1 2 0 -0.0002 7 0 0 0 8.65E+06 9.83E+06 - - - 2.014 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18770.18770.2 0.00991 24-Dec R.LIEETISIAMATK.E "sp|O95249|GOSR1_HUMAN,tr|E9PCW1|E9PCW1_HUMAN,tr|G5E9T8|G5E9T8_HUMAN" 3 1418.7691 0.67 14807 18770 2 1418.773378 710.3918 Golgi SNAP receptor complex member 1 OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 4.53 3603.8 - 424050 - - - 3.0378 - 1.962 0.382 - 366 1 2 0 0.0043 13 0 0 0 3.70E+06 5.56E+06 - - - 3.5908 0.8989 230117_WJC_METTL3_WT_vs_EV_F02.18775.18775.2 0.0126 16-Jul R.MVNHFIAEF.K "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1106.5219 - 14810 18775 2 1106.52614 554.2682 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.22 3604.2 - 5.13E+06 - - - 3.8309 - 1.549 0.415 - 180.1 1 1 0 0.0042 9 0 0 0 - - - - - 3.3709 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18776.18776.2 3.43E-05 16-Aug R.SPTWFGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1059.5502 0.97 14811 18776 2 1059.551505 530.7824 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3604.3 - 4.22E+06 - - - 1.2647 - 1.926 0.351 - 368.6 1 2 0 0.0013 9 0 0 0 4.67E+08 4.82E+08 - - - 3.5293 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18778.18778.2 0.00428 18-Oct R.FEELC[160.03]SDLFR.S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1314.5914 34.49 14813 18778 2 1314.592716 658.303 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.14 3604.4 - 2.32E+06 - - - 0.9722 - 1.967 0.461 - 379.4 1 2 0 0.0013 10 0 0 0 1.12E+07 3.24E+05 - - - 4.3339 0.9576 230117_WJC_METTL3_WT_vs_EV_F02.18779.18779.2 4.29 12-Jun R.TLIGFLR[166.11].S "sp|O15116|LSM1_HUMAN,tr|E5RH18|E5RH18_HUMAN,tr|E5RJ47|E5RJ47_HUMAN" 3 828.5097 1.52 14814 18779 2 828.509621 415.2621 U6 snRNA-associated Sm-like protein LSm1 OS=Homo sapiens OX=9606 GN=LSM1 PE=1 SV=1 9.41 3604.4 - 2.19E+06 - - - -0.0881 - 1.092 0.063 - 147.5 1 2 0 -0.0001 7 0 0 0 1.80E+07 1.19E+07 - - - -0.2148 0.9711 230117_WJC_METTL3_WT_vs_EV_F02.18780.18780.2 1.77 12-Jun R.NLPFLIK[136.11].K sp|Q86TB9|PATL1_HUMAN 1 851.536 1.11 14815 18780 2 851.536351 426.7753 Protein PAT1 homolog 1 OS=Homo sapiens OX=9606 GN=PATL1 PE=1 SV=2 8.75 3604.5 - 2.06E+06 - - - 0.3828 - 1.075 0.084 - 141.2 1 2 0 0.0003 7 0 0 0 1.67E+07 1.50E+07 - - - -0.1095 1 230117_WJC_METTL3_WT_vs_EV_F02.18781.18781.2 2.94E-05 13/18 R.IPDEIIDMVK[136.11].E "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1179.6301 2.21 14816 18781 2 1179.631916 590.8223 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 4.03 3604.6 - 1.79E+06 - - - 1.5717 - 2.373 0.427 - 533.7 1 2 0 0.0019 10 0 0 0 5.04E+07 2.28E+07 - - - 4.6064 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18784.18784.2 2.93E-05 18-Sep K.LYGEFADPFK.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1185.5706 1.99 14819 18784 2 1185.572249 593.7926 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3604.7 - 1.22E+06 - - - 1.369 - 1.624 0.532 - 233.5 1 2 0 0.0016 10 0 0 0 1.66E+07 8.35E+06 - - - 4.3233 0.9864 230117_WJC_METTL3_WT_vs_EV_F02.18786.18786.2 0.359 12-Jun K.LYSLFLK[136.11].Y "sp|Q9P2R7|SUCB1_HUMAN,tr|Q5T9Q5|Q5T9Q5_HUMAN,tr|A0A0U1RRI1|A0A0U1RRI1_HUMAN,tr|A0A2R8YDQ9|A0A2R8YDQ9_HUMAN,tr|A0A2R8Y6Y7|A0A2R8Y6Y7_HUMAN,tr|Q5T9Q8|Q5T9Q8_HUMAN" 6 890.5357 2.67 14821 18786 2 890.537945 446.2751 "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLA2 PE=1 SV=3" 8.59 3604.9 - 668721 - - - 2.5311 - 1.102 0.155 - 90 1 2 0 0.0023 7 0 0 0 1.80E+07 6.74E+06 - - - 0.4929 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18787.18787.2 3.92E-05 22-Sep K.IIATVLMTEDIK[136.11].L "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 1353.7669 0.07 14822 18787 2 1353.769295 677.8907 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 3605 - 650423 - - - 1.7773 - 2.284 0.454 - 172.6 1 2 0 0.0024 12 0 0 0 6.11E+05 8.26E+06 - - - 4.5666 0.9928 230117_WJC_METTL3_WT_vs_EV_F02.18795.18795.2 0.0571 14-Jun K.FEFLGINR.Q sp|Q8N3X1|FNBP4_HUMAN 1 994.5236 1.2 14828 18795 2 994.522595 498.2691 Formin-binding protein 4 OS=Homo sapiens OX=9606 GN=FNBP4 PE=1 SV=3 6 3606 - 1.43E+06 - - - -1.0266 - 1.443 0.181 - 104.8 1 2 0 -0.001 8 0 0 0 9.84E+06 8.22E+06 - - - 1.4836 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18796.18796.2 0.000238 14-Oct R.TSFLLNLR.R "sp|O00159|MYO1C_HUMAN,tr|F5H6E2|F5H6E2_HUMAN" 2 962.5549 0.4 14829 18796 2 962.556422 482.2847 Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4 9.41 3606.1 - 758331 - - - 1.5646 - 1.681 0.467 - 274 1 2 0 0.0015 8 0 0 0 2.81E+06 6.95E+06 - - - 4.0562 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18797.18797.2 0.045 20-Sep K.FLC[160.03]YLSQAGFR.V sp|Q7Z2T5|TRM1L_HUMAN 1 1360.6598 2.41 14830 18797 2 1360.661571 681.3372 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 8.22 3606.2 - 574496 - - - 1.3075 - 1.587 0.341 - 265 1 2 0 0.0018 11 0 0 0 7.85E+06 3.25E+06 - - - 2.8085 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.18798.18798.2 0.000475 20-Oct R.ELAMQTFGVLK[136.11].E sp|Q9NVP1|DDX18_HUMAN 1 1243.6726 0.001 14831 18798 2 1243.677891 622.8436 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 6.1 3606.3 - 496998 - - - 4.2584 - 2.06 0.427 - 229.7 1 2 0 0.0053 11 0 0 0 0.00E+00 1.60E+06 - - - 4.1482 0.9858 230117_WJC_METTL3_WT_vs_EV_F02.18803.18803.2 0.153 30-Jul K.QLTQILPVNSLQTEDR.M tr|I3L1N3|I3L1N3_HUMAN 1 1853.9847 999 14836 18803 2 1853.988758 927.9996 Phosphorylase b kinase regulatory subunit (Fragment) OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=1 4.37 3607 - 255273 - - - 2.1937 - 1.526 0.055 - 112.3 2 2 0 0.0041 16 0 0 0 4.74E+06 0.00E+00 - - - 0.3506 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.18809.18809.2 3.38 16-Nov K.ELIEELIAK[136.11].S "sp|P78316|NOP14_HUMAN,tr|E9PFK5|E9PFK5_HUMAN" 2 1064.6209 0.73 14840 18809 2 1064.622212 533.3177 Nucleolar protein 14 OS=Homo sapiens OX=9606 GN=NOP14 PE=1 SV=3 4.25 3607.6 - 5.82E+06 - - - 1.254 - 1.899 0.222 - 376.8 1 2 0 0.0013 9 0 0 0 3.32E+07 4.55E+07 - - - 2.5357 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.18810.18810.2 0.0294 16-Sep K.GLALWEAYR.E "sp|Q15020|SART3_HUMAN,tr|F8VVK9|F8VVK9_HUMAN,tr|A0A494C0L2|A0A494C0L2_HUMAN,tr|F8W667|F8W667_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN,tr|F8VZM2|F8VZM2_HUMAN" 6 1077.5607 3.25 14841 18810 2 1077.561552 539.7876 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 3607.7 - 2.56E+06 - - - 0.7628 - 1.975 0.22 - 465 1 2 0 0.0008 9 0 0 0 2.55E+07 7.85E+06 - - - 2.6346 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.18811.18811.2 0.0156 16-Aug K.LFTTMELMR[166.11].W sp|O00232|PSD12_HUMAN 1 1150.5754 1.79 14842 18811 2 1150.578302 576.295 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 6 3607.7 - 2.09E+06 - - - 2.5161 - 1.517 0.328 - 151.7 1 2 0 0.0029 9 0 0 0 2.46E+07 1.37E+07 - - - 2.6683 0.999 230117_WJC_METTL3_WT_vs_EV_F02.18812.18812.2 2.15 16-Dec R.ALVAVLLSR[166.11].T sp|Q92616|GCN1_HUMAN 1 950.6152 1.12 14843 18812 2 950.616192 476.3149 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.79 3607.9 - 1.97E+06 - - - 1.0204 - 2.123 0.168 - 693 1 2 0 0.001 9 0 0 0 1.70E+07 1.52E+07 - - - 2.4595 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.18814.18814.2 0.0245 18-Oct K.LYGEFADPFK[136.11].L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1193.5848 1.99 14845 18814 2 1193.588987 597.7997 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3608.1 - 1.12E+06 - - - 3.4861 - 1.395 0.431 - 228.3 1 2 0 0.0042 10 0 0 0 1.66E+07 8.35E+06 - - - 3.1523 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18816.18816.2 0.000488 20-Dec K.FLC[160.03]YLSQAGFR[166.11].V sp|Q7Z2T5|TRM1L_HUMAN 1 1370.6681 2.41 14847 18816 2 1370.671656 686.3413 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 8.22 3608.3 - 653630 - - - 2.6221 - 2.176 0.447 - 589.3 1 2 0 0.0036 11 0 0 0 7.85E+06 3.25E+06 - - - 4.4447 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18825.18825.2 0.00134 20-Oct K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 0.93 14854 18825 2 1197.722147 599.8679 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3609.3 - 6.93E+06 - - - 0.7406 - 2.239 0.437 - 370.9 1 2 0 0.0009 11 0 0 0 1.24E+09 1.33E+09 - - - 4.4489 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18826.18826.2 0.00137 20-Oct K.IGDFGLVTSLK.N "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 3 1148.6441 5.44 14855 18826 2 1148.64632 575.3293 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 5.84 3609.4 - 5.76E+06 - - - 1.9109 - 2.173 0.361 - 212.9 1 2 0 0.0022 11 0 0 0 4.25E+07 7.82E+06 - - - 3.8062 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18827.18827.2 3.66E-07 20-Dec K.VANVSLLALYK.G sp|P62266|RS23_HUMAN 1 1189.7071 0.93 14856 18827 2 1189.707605 595.8608 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3609.4 - 4.93E+06 - - - 0.4581 - 2.589 0.361 - 668.8 1 2 0 0.0005 11 0 0 0 1.24E+09 1.33E+09 - - - 4.2806 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.18828.18828.2 0.0381 16-Oct R.ALVAVLLSR.T sp|Q92616|GCN1_HUMAN 1 940.607 0.97 14857 18828 2 940.60762 471.3108 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.79 3609.5 - 3.76E+06 - - - 0.7102 - 2.074 0.169 - 410.8 1 2 0 0.0007 9 0 0 0 1.48E+07 1.52E+07 - - - 2.3994 1 230117_WJC_METTL3_WT_vs_EV_F02.18832.18832.2 5.00E-05 20-Sep K.LYLNETFSELR.L "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C3Z5|H7C3Z5_HUMAN" 3 1383.7034 3.27 14861 18832 2 1383.704393 692.859 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 4.53 3609.9 - 908548 - - - 0.6952 - 2.379 0.511 - 256.1 1 2 0 0.001 11 0 0 0 6.03E+06 1.84E+06 - - - 5.1595 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.18833.18833.2 0.0637 18-Oct R.SIIFANYIAR.D "sp|Q7L523|RRAGA_HUMAN,sp|Q5VZM2|RRAGB_HUMAN,tr|Q5VZM0|Q5VZM0_HUMAN" 3 1166.6448 1.71 14862 18833 2 1166.645262 584.3297 Ras-related GTP-binding protein A OS=Homo sapiens OX=9606 GN=RRAGA PE=1 SV=1 8.46 3610 - 732379 - - - 0.4012 - 1.756 0.308 - 310.8 1 2 0 0.0005 10 0 0 0 7.96E+06 4.66E+06 - - - 2.8874 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.18834.18834.2 0.00426 24-Aug R.IELVVAPAGVTLK[136.11].E "sp|P20839|IMDH1_HUMAN,tr|C9J381|C9J381_HUMAN,tr|C9K0R9|C9K0R9_HUMAN,tr|A0A3B3IRL5|A0A3B3IRL5_HUMAN" 4 1316.8159 1.02 14863 18834 2 1316.815557 659.4152 Inosine-5'-monophosphate dehydrogenase 1 OS=Homo sapiens OX=9606 GN=IMPDH1 PE=1 SV=2 6 3610.2 - 650654 - - - -0.2514 - 1.882 0.37 - 137.1 1 2 0 -0.0003 13 0 0 0 7.04E+06 6.92E+06 - - - 3.3966 1 230117_WJC_METTL3_WT_vs_EV_F02.18837.18837.2 0.000345 18-Dec R.ILVATNLFGR.G "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 6 1102.6499 1.38 14864 18837 2 1102.650242 552.3322 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 9.75 3610.6 - 1.91E+07 - - - 0.3292 - 2.343 0.456 - 503.1 1 2 0 0.0004 10 0 0 0 4.12E+08 2.99E+08 - - - 4.7855 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18838.18838.2 0.0731 18-Nov R.ILVATNLFGR[166.11].G "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 6 1112.6581 1.38 14865 18838 2 1112.659456 557.3364 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 9.75 3610.6 - 1.63E+07 - - - 1.1747 - 2.15 0.375 - 429.4 1 2 0 0.0013 10 0 0 0 4.12E+08 2.99E+08 - - - 3.947 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18839.18839.2 0.00154 18-Oct R.FLLQDTVELR.E "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1232.6765 1.87 14866 18839 2 1232.676504 617.3455 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3610.6 - 8.18E+06 - - - 0.013 - 2.196 0.359 - 403.1 1 2 0 0 10 0 0 0 2.07E+08 1.11E+08 - - - 3.8883 1 230117_WJC_METTL3_WT_vs_EV_F02.18845.18845.2 6.92E-05 13/22 K.TALALEVGDIVK.V sp|P46109|CRKL_HUMAN 1 1227.7075 10.55 14872 18845 2 1227.708888 614.861 Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1 4.37 3611.1 - 1.43E+06 - - - 1.168 - 2.119 0.487 - 414.3 1 2 0 0.0014 12 0 0 0 1.09E+07 1.03E+06 - - - 4.6134 1 230117_WJC_METTL3_WT_vs_EV_F02.18848.18848.2 2.33E-05 24-Dec K.AEPLLGAPGELLK.Q sp|P17482|HXB9_HUMAN 1 1306.7497 3.11 14875 18848 2 1306.748365 654.3821 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 3611.4 - 1.01E+06 - - - -0.9857 - 2.131 0.498 - 432.5 1 2 0 -0.0013 13 0 0 0 2.14E+07 6.87E+06 - - - 4.6606 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18855.18855.2 0.0254 16-Oct R.YLTVAAVFR.G "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 5 1038.5862 2.84 14880 18855 2 1038.587034 520.3004 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3612.3 - 1.74E+07 - - - 0.7876 - 2.083 0.459 - 371.5 1 2 0 0.0008 9 0 0 0 1.21E+09 4.27E+08 - - - 4.5539 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.18859.18859.2 0.288 14-Aug K.TVALWDLR.N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 972.5393 1.94 14884 18859 2 972.539916 487.2769 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3612.5 - 3.28E+06 - - - 0.6684 - 1.419 0.263 - 256.5 1 2 0 0.0006 8 0 0 0 7.16E+08 3.69E+08 - - - 2.0388 0.997 230117_WJC_METTL3_WT_vs_EV_F02.18861.18861.2 0.0409 14-Jul K.TVALWDLR[166.11].N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 982.5475 1.94 14886 18861 2 982.547727 492.281 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3612.7 - 1.75E+06 - - - 0.1944 - 1.316 0.236 - 177.7 1 2 0 0.0002 8 0 0 0 7.16E+08 3.69E+08 - - - 1.6122 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.18872.18872.2 0.0588 12-Sep R.FVLNLIK.L sp|Q8TDN6|BRX1_HUMAN 1 845.5375 0.75 14894 18872 2 845.536846 423.776 Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2 8.75 3613.9 - 670433 - - - -0.7439 - 1.726 0.14 - 234.9 1 2 0 -0.0006 7 0 0 0 4.38E+07 5.86E+07 - - - 1.8043 1 230117_WJC_METTL3_WT_vs_EV_F02.18877.18877.2 6.09E-06 18-Nov R.FEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1252.6088 11.79 14897 18877 2 1252.607199 627.3117 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3614.5 - 1.03E+07 - - - -1.2797 - 2.146 0.564 - 396.1 1 2 0 -0.0016 10 0 0 0 9.90E+08 8.40E+07 - - - 5.3377 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.18880.18880.2 0.0317 16-Oct R.LDALLAELR[166.11].A sp|Q96L58|B3GT6_HUMAN 1 1022.6 1.45 14900 18880 2 1022.599278 512.3073 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 4.37 3614.9 - 2.77E+06 - - - -0.6728 - 2.214 0.168 - 318.4 1 2 0 -0.0007 9 0 0 0 2.72E+07 1.88E+07 - - - 2.581 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.18881.18881.2 0.125 14-Aug R.ILLTLGIR.L "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 897.6011 0.93 14901 18881 2 897.599241 449.8078 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 9.75 3615 - 2.07E+06 - - - -2.1134 - 1.68 0.329 - 196.2 1 2 0 -0.0019 8 0 0 0 1.11E+07 1.20E+07 - - - 3.0351 1 230117_WJC_METTL3_WT_vs_EV_F02.18883.18883.2 3.34E-05 22-Dec K.SLAMEMVLTGDR.L sp|P30084|ECHM_HUMAN 1 1321.637 1.27 14903 18883 2 1321.635482 661.8258 "Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4" 4.37 3615.2 - 1.33E+06 - - - -1.1546 - 2.429 0.491 - 245.3 1 2 0 -0.0015 12 0 0 0 8.52E+06 6.70E+06 - - - 5.0022 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.18886.18886.2 0.000196 22-Nov K.SLAMEMVLTGDR[166.11].L sp|P30084|ECHM_HUMAN 1 1331.6453 1.25 14906 18886 2 1331.642598 666.8299 "Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4" 4.37 3615.6 - 1.14E+06 - - - -2.0125 - 2.273 0.417 - 388.3 1 2 0 -0.0027 12 0 0 0 8.52E+06 6.82E+06 - - - 4.2806 0.998 230117_WJC_METTL3_WT_vs_EV_F02.18887.18887.2 0.0314 18-Oct R.FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1262.6171 11.79 14907 18887 2 1262.614364 632.3158 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3615.8 - 967606 - - - -2.1448 - 2.065 0.37 - 347.2 1 2 0 -0.0027 10 0 0 0 9.90E+08 8.40E+07 - - - 3.797 0.8998 230117_WJC_METTL3_WT_vs_EV_F02.18891.18891.2 0.641 16-Aug K.FSLFSAAVR[166.11].E "sp|Q96ER9|MITOK_HUMAN,sp|Q8NDN9|RCBT1_HUMAN" 2 1006.5475 4.99 14911 18891 2 1006.543231 504.281 Mitochondrial potassium channel OS=Homo sapiens OX=9606 GN=CCDC51 PE=1 SV=2 9.75 3616.3 - 494134 - - - -4.277 - 1.48 0.105 - 148.6 1 2 0 -0.0043 9 0 0 0 1.41E+07 2.82E+06 - - - 0.9494 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18896.18896.2 0.00993 18-Nov K.IEVIEIMTDR[166.11].G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1227.6408 0.87 14914 18896 2 1227.640344 614.8277 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3616.9 - 4.68E+06 - - - -0.4073 - 2.424 0.317 - 532.5 1 2 0 -0.0005 10 0 0 0 1.82E+08 2.10E+08 - - - 3.8537 0.9785 230117_WJC_METTL3_WT_vs_EV_F02.18897.18897.2 8.63 12-Jun R.VLFLIPK.N "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q5JV98|Q5JV98_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|H0Y630|H0Y630_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 13 828.5473 2.06 14915 18897 2 828.547649 415.2809 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 8.72 3616.9 - 2.99E+06 - - - 0.4067 - 1.118 0.122 - 127.3 3 2 0 0.0003 7 0 0 0 3.22E+07 1.57E+07 - - - 0.0823 0.9907 230117_WJC_METTL3_WT_vs_EV_F02.18899.18899.2 0.0615 12-Aug K.WMGIAFR[166.11].L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 889.4508 1.16 14917 18899 2 889.450366 445.7327 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.75 3617.1 - 2.62E+06 - - - -0.4868 - 1.115 0.22 - 269 1 2 0 -0.0004 7 0 0 0 2.84E+07 2.46E+07 - - - 1.0107 0.9964 230117_WJC_METTL3_WT_vs_EV_F02.18901.18901.2 0.111 12-Aug K.WMGIAFR.L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 879.4425 1.17 14919 18901 2 879.442034 440.7285 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.75 3617.2 - 2.04E+06 - - - -0.5629 - 1.391 0.236 - 256.1 1 2 0 -0.0005 7 0 0 0 2.88E+07 2.46E+07 - - - 1.8296 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.18902.18902.2 0.027 12-Jun R.VLFLIPK[136.11].N "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q5JV98|Q5JV98_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|H0Y630|H0Y630_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 13 836.5615 2.06 14920 18902 2 836.561055 419.288 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 8.72 3617.4 - 1.45E+06 - - - -0.5463 - 1.341 0.366 - 77.5 1 2 0 -0.0005 7 0 0 0 3.22E+07 1.57E+07 - - - 2.6738 0.9907 230117_WJC_METTL3_WT_vs_EV_F02.18904.18904.2 0.136 18-Aug R.FLITSNLELR.K tr|H0Y4V9|H0Y4V9_HUMAN 1 1204.6816 0.9 14922 18904 2 1204.679249 603.3481 La-related protein 4B (Fragment) OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=1 6 3617.6 - 1.02E+06 - - - -1.9291 - 1.616 0.188 - 188.6 1 2 0 -0.0023 10 0 0 0 1.53E+07 1.69E+07 - - - 1.7685 0.999 230117_WJC_METTL3_WT_vs_EV_F02.18909.18909.2 0.0218 18-Dec K.IEVIEIMTDR.G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1217.6326 0.87 14925 18909 2 1217.631064 609.8236 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3618.2 - 2.81E+06 - - - -1.2401 - 2.392 0.343 - 626 1 2 0 -0.0015 10 0 0 0 1.82E+08 2.10E+08 - - - 4.0083 0.9442 230117_WJC_METTL3_WT_vs_EV_F02.18913.18913.2 0.0228 12-Aug L.SGFLVWR[166.11].R "sp|Q9NP84|TNR12_HUMAN,sp|Q96T88|UHRF1_HUMAN,tr|I3L1J9|I3L1J9_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 6 873.4736 1.64 14929 18913 2 873.474969 437.7441 Tumor necrosis factor receptor superfamily member 12A OS=Homo sapiens OX=9606 GN=TNFRSF12A PE=1 SV=1 9.47 3618.4 - 794512 - - - 1.5181 - 1.75 0.258 - 256.3 1 1 0 0.0013 7 0 0 0 1.48E+07 9.01E+06 - - - 2.7193 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18917.18917.2 0.000357 20-Dec R.IGFVGFPSVGK.S sp|Q9Y295|DRG1_HUMAN 1 1106.6124 1.98 14931 18917 2 1106.613644 554.3135 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 8.75 3618.9 - 4.40E+06 - - - 1.0961 - 2.064 0.446 - 369.5 1 2 0 0.0012 11 0 0 0 6.86E+07 3.47E+07 - - - 4.2951 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.18919.18919.2 0.164 16-Sep R.VEFILEQMR.L sp|O00232|PSD12_HUMAN 1 1163.6009 1.97 14933 18919 2 1163.600288 582.8077 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.53 3619.2 - 1.12E+06 - - - -0.5088 - 2.025 0.38 - 450.7 1 2 0 -0.0006 9 0 0 0 1.32E+07 6.70E+06 - - - 3.8887 1 230117_WJC_METTL3_WT_vs_EV_F02.18926.18926.2 1.69E-06 13/20 K.TPPPVLIFAEK.K sp|Q9UJV9|DDX41_HUMAN 1 1210.6962 1.64 14938 18926 2 1210.69705 606.3554 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3620.1 - 5.97E+06 - - - 0.7343 - 2.193 0.472 - 520.1 1 2 0 0.0009 11 0 0 0 9.71E+07 5.91E+07 - - - 4.6513 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18929.18929.2 0.0473 14/22 K.IIENELEGFGIR.L sp|Q9Y295|DRG1_HUMAN 1 1388.73 1.79 14941 18929 2 1388.731362 695.3723 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3620.4 - 698429 - - - 0.9952 - 2.308 0.39 - 663.3 1 2 0 0.0014 12 0 0 0 1.64E+07 9.16E+06 - - - 4.1218 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18930.18930.2 0.00265 13/22 K.IIENELEGFGIR[166.11].L sp|Q9Y295|DRG1_HUMAN 1 1398.7383 1.79 14942 18930 2 1398.740624 700.3764 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3620.6 - 529092 - - - 1.6972 - 2.564 0.361 - 489 1 2 0 0.0024 12 0 0 0 1.64E+07 9.16E+06 - - - 4.184 1 230117_WJC_METTL3_WT_vs_EV_F02.18931.18931.2 4.13E-05 14/24 R.ILLAEVPTMAVEK[136.11].V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1420.8091 6.16 14943 18931 2 1420.807686 711.4118 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3620.7 - 488755 - - - -0.9875 - 2.606 0.477 - 571.1 1 2 0 -0.0014 13 0 0 0 5.45E+07 8.84E+06 - - - 5.0219 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18932.18932.2 4.42E-05 20-Oct R.YLLEQDFPGMR.L "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN" 2 1367.6544 2.16 14944 18932 2 1367.657429 684.8345 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.37 3620.8 - 429619 - - - 2.2352 - 1.903 0.346 - 415.8 1 2 0 0.0031 11 0 0 0 2.95E+06 1.37E+06 - - - 3.3362 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.18933.18933.3 0.00765 15/40 R.ILVTLLHTLER[166.11].M sp|Q9BWD1|THIC_HUMAN 1 1316.8055 1.33 14945 18933 3 1316.806907 439.9425 "Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2" 6.75 3621 - 423385 - - - 1.0366 - 2.804 0.346 - 321.7 1 2 0 0.0014 11 0 0 0 1.09E+07 8.15E+06 - - - 5.3262 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.18934.18934.2 4.41E-07 22-Oct K.YMGAAAMYLISK.R "sp|Q9H7Z7|PGES2_HUMAN,tr|A0A7I2V5T7|A0A7I2V5T7_HUMAN,tr|A6NHH0|A6NHH0_HUMAN,tr|X6RJ95|X6RJ95_HUMAN,tr|A0A7I2V5X6|A0A7I2V5X6_HUMAN" 5 1317.6461 3.33 14946 18934 2 1317.645861 659.8303 Prostaglandin E synthase 2 OS=Homo sapiens OX=9606 GN=PTGES2 PE=1 SV=1 8.5 3621.1 - 311630 - - - -0.1935 - 2.002 0.477 - 218.5 1 2 0 -0.0003 12 0 0 0 4.91E+06 1.48E+06 - - - 4.3905 0.9957 230117_WJC_METTL3_WT_vs_EV_F02.18936.18936.2 0.0356 16-Jul R.YQFTPAFLR.L "sp|Q13432|U119A_HUMAN,sp|A6NIH7|U119B_HUMAN,tr|K7EN86|K7EN86_HUMAN,tr|C9JSK0|C9JSK0_HUMAN,tr|K7EJU3|K7EJU3_HUMAN" 5 1141.592 1.81 14948 18936 2 1141.595556 571.8033 Protein unc-119 homolog A OS=Homo sapiens OX=9606 GN=UNC119 PE=1 SV=1 8.75 3621.4 - 299041 - - - 3.0887 - 1.494 0.194 - 130.7 1 2 0 0.0035 9 0 0 0 2.80E+06 1.54E+06 - - - 1.6342 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.18938.18938.2 0.0253 16-Jul K.ITPLMAAFR.K "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1018.5634 2.18 14950 18938 2 1018.565391 510.289 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 9.75 3621.6 - 208447 - - - 1.9822 - 1.569 0.243 - 136.8 2 2 0 0.002 9 0 0 0 9.59E+06 4.41E+06 - - - 2.0038 0.9953 230117_WJC_METTL3_WT_vs_EV_F02.18939.18939.2 7.01E-05 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 8.49 14951 18939 2 1006.576266 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3621.7 - 194343 - - - 6.3264 - 1.873 0.469 - 267.8 1 2 0 0.0064 9 0 0 0 4.08E+07 4.81E+06 - - - 4.3185 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.18940.18940.2 0.00221 24-Sep R.LDYLGVSYGLTPR[166.11].L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1462.7695 0.95 14952 18940 2 1462.774233 732.3921 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.83 3621.9 - 162137 - - - 3.2015 - 2.032 0.47 - 127.8 1 2 0 0.0047 13 0 0 0 6.92E+06 7.26E+06 - - - 4.3307 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.18946.18946.2 0.0177 14-Aug R.DFVNYLVR[166.11].L sp|Q08211|DHX9_HUMAN 1 1034.5425 0.93 14956 18946 2 1034.545004 518.2785 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.84 3622.7 - 3.92E+07 - - - 2.4678 - 1.738 0.303 - 266.2 1 2 0 0.0026 8 0 0 0 2.69E+08 2.89E+08 - - - 2.9452 1 230117_WJC_METTL3_WT_vs_EV_F02.18947.18947.2 0.000189 20-Nov K.FAVALLDDSVR.V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1204.6452 2.15 14957 18947 2 1204.647842 603.3299 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 4.21 3622.8 - 2.17E+06 - - - 2.2031 - 2.38 0.489 - 415.9 1 2 0 0.0027 11 0 0 0 2.45E+07 1.14E+07 - - - 4.9976 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.18952.18952.2 0.13 16-Sep K.GLDFALLQK[136.11].V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1011.5844 1.22 14962 18952 2 1011.587971 506.7995 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3623.2 - 1.24E+06 - - - 3.4985 - 1.775 0.37 - 206.5 1 2 0 0.0035 9 0 0 0 5.07E+07 4.16E+07 - - - 3.4327 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18953.18953.2 0.0119 18-Oct R.TLDLPIYVTR.V "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 5 1189.6707 0.41 14963 18953 2 1189.671655 595.8426 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.5 3623.3 - 1.24E+06 - - - 0.8246 - 1.759 0.363 - 364.4 1 2 0 0.001 10 0 0 0 9.15E+06 2.21E+07 - - - 3.2982 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.18954.18954.2 0.00471 16-Sep R.VSFELFADK.V "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|F8WE65|F8WE65_HUMAN,tr|A0A7I2V5J5|A0A7I2V5J5_HUMAN" 4 1054.5335 -1 14964 18954 2 1054.538571 528.274 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 4.37 3623.4 - 957375 - - - 4.7974 - 1.917 0.384 - 249.8 1 2 0 0.0051 9 0 0 0 0.00E+00 0.00E+00 - - - 3.7583 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.18955.18955.2 0.017 14-Aug R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 0.95 14965 18955 2 898.525564 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 3623.5 - 767556 - - - 2.168 - 1.677 0.116 - 142.7 1 2 0 0.0019 8 0 0 0 1.14E+07 1.19E+07 - - - 1.4564 1 230117_WJC_METTL3_WT_vs_EV_F02.18956.18956.2 2.10E-06 14/24 R.LDYLGVSYGLTPR.L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1452.7613 0.95 14966 18956 2 1452.765071 727.3879 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.83 3623.6 - 405658 - - - 2.6095 - 2.569 0.579 - 548.5 1 2 0 0.0038 13 0 0 0 6.92E+06 7.26E+06 - - - 5.7379 1 230117_WJC_METTL3_WT_vs_EV_F02.18957.18957.2 1.87E-07 17/20 M.PPYTVVYFPVR[166.11].G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1346.7262 1.24 14967 18957 2 1346.734381 674.3704 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3623.7 - 368984 - - - 6.0532 - 2.68 0.515 - 495.1 1 2 0 0.0082 11 0 0 0 7.52E+07 6.07E+07 - - - 5.5091 0.999 230117_WJC_METTL3_WT_vs_EV_F02.18965.18965.2 0.181 20-Oct R.IGFVGFPSVGK[136.11].S sp|Q9Y295|DRG1_HUMAN 1 1114.6266 2.02 14974 18965 2 1114.628417 558.3206 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 8.75 3624.8 - 4.37E+06 - - - 1.6023 - 1.577 0.289 - 208.2 1 2 0 0.0018 11 0 0 0 6.85E+07 3.40E+07 - - - 2.4073 0.999 230117_WJC_METTL3_WT_vs_EV_F02.18967.18967.2 0.00164 16-Aug K.GLDFALLQK.V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1003.5702 1.21 14976 18967 2 1003.573571 502.7924 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3624.9 - 1.16E+07 - - - 3.3271 - 1.766 0.366 - 181.6 1 2 0 0.0033 9 0 0 0 4.97E+07 4.12E+07 - - - 3.3886 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.18968.18968.2 0.00399 14-Aug R.DLTDYLMK.L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 997.479 1.15 14977 18968 2 997.482317 499.7468 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3624.9 - 8.29E+06 - - - 3.2913 - 1.513 0.376 - 189.8 1 2 0 0.0033 8 0 0 0 7.21E+07 6.26E+07 - - - 3.066 1 230117_WJC_METTL3_WT_vs_EV_F02.18971.18971.2 1.32E-06 15/22 K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 2.06 14980 18971 2 1263.693371 632.853 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3625.2 - 3.25E+06 - - - 1.5471 - 2.394 0.51 - 557.7 1 2 0 0.002 12 0 0 0 2.48E+07 1.20E+07 - - - 5.1042 1 230117_WJC_METTL3_WT_vs_EV_F02.18973.18973.2 2.11E-06 17/20 M.PPYTVVYFPVR.G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1336.718 1.21 14982 18973 2 1336.718753 669.3663 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3625.4 - 2.59E+06 - - - 0.594 - 2.991 0.564 - 1457.1 1 2 0 0.0008 11 0 0 0 7.52E+07 6.19E+07 - - - 6.1703 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.18975.18975.2 0.0311 14-Oct R.ITNWLVLK.N "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN,tr|H3BRT3|H3BRT3_HUMAN" 3 985.5961 -1 14984 18975 2 985.598273 493.8053 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 8.75 3625.6 - 1.73E+06 - - - 2.2524 - 2.074 0.417 - 226.5 1 2 0 0.0022 8 0 0 0 0.00E+00 0.00E+00 - - - 4.3203 0.9914 230117_WJC_METTL3_WT_vs_EV_F02.18980.18980.2 0.0545 12-May K.DYVDLFR.H sp|P78527|PRKDC_HUMAN 1 926.4498 0.43 14989 18980 2 926.453767 464.2322 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.21 3626.2 - 794825 - - - 4.3014 - 1.17 0.296 - 103.6 1 2 0 0.004 7 0 0 0 1.91E+07 4.46E+07 - - - 1.7235 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.18982.18982.2 0.00588 20-Sep R.LEPLVNDLTLR.L sp|Q70UQ0|IKIP_HUMAN 1 1281.7293 2.7 14991 18982 2 1281.735478 641.8719 Inhibitor of nuclear factor kappa-B kinase-interacting protein OS=Homo sapiens OX=9606 GN=IKBIP PE=1 SV=1 4.37 3626.5 - 686457 - - - 4.8575 - 1.757 0.359 - 302.2 1 2 0 0.0062 11 0 0 0 3.30E+07 1.22E+07 - - - 3.2153 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.18988.18988.2 0.00025 16-Sep K.GFGFVSFER[166.11].H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1054.5112 0.99 14996 18988 2 1054.515305 528.2629 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3627.1 - 1.33E+07 - - - 3.9393 - 1.8 0.446 - 277.3 1 2 0 0.0042 9 0 0 0 5.46E+08 5.53E+08 - - - 4.0343 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.18989.18989.2 2.60E-05 16-Sep K.GFGFVSFER.H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1044.5029 0.99 14997 18989 2 1044.506956 523.2587 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3627.2 - 1.02E+07 - - - 3.9014 - 1.937 0.387 - 310.3 1 2 0 0.0041 9 0 0 0 5.46E+08 5.53E+08 - - - 3.8108 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.18990.18990.2 0.00186 16-Nov K.LTQILSYLR.Q sp|Q13123|RED_HUMAN 1 1105.6495 1.44 14998 18990 2 1105.653958 553.832 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3627.3 - 5.80E+06 - - - 3.9913 - 2.328 0.412 - 595.1 1 2 0 0.0044 9 0 0 0 1.24E+08 8.66E+07 - - - 4.5273 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.18991.18991.2 0.214 16-Nov K.LTQILSYLR[166.11].Q sp|Q13123|RED_HUMAN 1 1115.6578 1.43 14999 18991 2 1115.66255 558.8362 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3627.3 - 5.52E+06 - - - 4.2441 - 2.31 0.415 - 602.9 1 2 0 0.0047 9 0 0 0 1.24E+08 8.65E+07 - - - 4.5269 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.18992.18992.2 0.00494 14-Sep K.IDILTELR[166.11].D "sp|O00139|KIF2A_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 981.5734 1.07 15000 18992 2 981.577384 491.794 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.37 3627.4 - 3.10E+06 - - - 4.0415 - 2.019 0.32 - 283.5 1 2 0 0.004 8 0 0 0 9.35E+07 8.71E+07 - - - 3.5223 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.18994.18994.2 2.31E-05 22-Dec K.NIEDVIAQGIGK.L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1255.6772 2.08 15002 18994 2 1255.681074 628.8459 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3627.6 - 1.85E+06 - - - 3.0724 - 2.124 0.468 - 275.1 1 2 0 0.0039 12 0 0 0 2.51E+07 1.21E+07 - - - 4.4785 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.18996.18996.2 0.000965 20-Nov K.TPPPVLIFAEK[136.11].K sp|Q9UJV9|DDX41_HUMAN 1 1218.7104 1.64 15004 18996 2 1218.714416 610.3625 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3627.8 - 1.32E+06 - - - 3.3273 - 1.438 0.385 - 337.6 1 2 0 0.0041 11 0 0 0 9.71E+07 5.91E+07 - - - 2.866 0.9924 230117_WJC_METTL3_WT_vs_EV_F02.18997.18997.2 0.077 20-Oct R.TVPILFASTVR.R sp|Q6P1M0|S27A4_HUMAN 1 1202.7023 0.55 15005 18997 2 1202.709563 602.3584 Long-chain fatty acid transport protein 4 OS=Homo sapiens OX=9606 GN=SLC27A4 PE=1 SV=1 9.41 3627.9 - 717166 - - - 6.0314 - 1.648 0.369 - 259.5 1 2 0 0.0073 11 0 0 0 1.20E+07 2.19E+07 - - - 3.1156 1 230117_WJC_METTL3_WT_vs_EV_F02.18998.18998.2 0.000139 13/18 K.C[160.03]LEEFELLGK.A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1236.606 1.02 15006 18998 2 1236.610918 619.3103 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3628 - 704160 - - - 3.9568 - 2.132 0.523 - 442.9 1 2 0 0.0049 10 0 0 0 1.31E+07 1.29E+07 - - - 5.0155 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.19001.19001.2 0.0203 24-May R.LLPPEDTQELIFK[136.11].D sp|O60287|NPA1P_HUMAN 1 1549.8483 1.14 15009 19001 2 1549.851394 775.9314 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 4.14 3628.4 - 76969.6 - - - 1.9892 - 1.35 0.287 - 51.1 1 2 0 0.0031 13 0 0 0 2.09E+06 1.82E+06 - - - 1.93 0.997 230117_WJC_METTL3_WT_vs_EV_F02.19002.19002.2 0.00817 Jul-34 K.SSGPTSLFAVTVAPPGAR.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1713.905 1.06 15010 19002 2 1713.903958 857.9598 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3628.5 - 0 - - - -0.5986 - 1.333 0.31 - 46 1 2 0 -0.001 18 0 0 0 8.46E+05 8.01E+05 - - - 2.037 1 230117_WJC_METTL3_WT_vs_EV_F02.19005.19005.2 0.00159 20-Nov R.LMMDPLTGLNR[166.11].G "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1269.6449 0.94 15012 19005 2 1269.648563 635.8297 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.84 3628.9 - 3.24E+06 - - - 2.8977 - 2.163 0.499 - 356.6 1 2 0 0.0037 11 0 0 0 2.51E+07 2.67E+07 - - - 4.8125 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19007.19007.2 0.0057 14-Jul R.DLTDYLMK[136.11].L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 1005.4932 1.15 15014 19007 2 1005.494949 503.7539 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3629 - 8.62E+06 - - - 1.7056 - 1.438 0.382 - 150.7 1 2 0 0.0017 8 0 0 0 7.22E+07 6.26E+07 - - - 2.9575 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19008.19008.2 0.000241 20-Aug R.LMMDPLTGLNR.G "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1259.6366 0.83 15015 19008 2 1259.638829 630.8256 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.84 3629.1 - 2.69E+06 - - - 1.7584 - 1.623 0.46 - 189.3 1 2 0 0.0022 11 0 0 0 2.21E+07 2.65E+07 - - - 3.7479 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.19009.19009.3 0.00101 Nov-36 R.DFLLKPELLR.A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1242.7336 1.03 15016 19009 3 1242.73602 415.2518 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3629.1 - 2.33E+06 - - - 1.9401 - 2.149 0.438 - 164.6 1 2 0 0.0024 10 0 0 0 3.37E+07 3.27E+07 - - - 5.6567 0.9952 230117_WJC_METTL3_WT_vs_EV_F02.19010.19010.2 0.124 18-Jul K.LLLGDLAPVR.G sp|Q9NUQ8|ABCF3_HUMAN 1 1065.6546 4.76 15017 19010 2 1065.655779 533.8346 ATP-binding cassette sub-family F member 3 OS=Homo sapiens OX=9606 GN=ABCF3 PE=1 SV=2 5.84 3629.2 - 2.26E+06 - - - 1.0782 - 1.338 0.158 - 94.2 1 2 0 0.0011 10 0 0 0 1.61E+07 3.37E+06 - - - 1.0204 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19016.19016.2 0.113 18-Sep R.LLLDTLQLSK.- "sp|O15357|SHIP2_HUMAN,tr|H7BXR2|H7BXR2_HUMAN" 2 1142.6911 2.64 15021 19016 2 1142.693521 572.3528 "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 OS=Homo sapiens OX=9606 GN=INPPL1 PE=1 SV=2" 5.84 3629.9 - 736430 - - - 2.1406 - 1.838 0.357 - 177 1 2 0 0.0024 10 0 0 0 1.12E+07 4.23E+06 - - - 3.376 0.9896 230117_WJC_METTL3_WT_vs_EV_F02.19017.19017.2 0.474 12-Aug R.WLLELSK[136.11].K sp|P35573|GDE_HUMAN 1 895.5259 0.69 15022 19017 2 895.524034 448.7702 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 6 3630 - 1.13E+06 - - - -2.0323 - 1.539 0.178 - 169.7 1 2 0 -0.0018 7 0 0 0 1.76E+07 2.56E+07 - - - 1.7212 0.9808 230117_WJC_METTL3_WT_vs_EV_F02.19018.19018.2 0.00154 18-Nov K.TIC[160.03]AEFAILR.M "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1192.6274 0.99 15023 19018 2 1192.62073 597.321 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.66 3630.1 - 1.07E+06 - - - -5.617 - 1.634 0.43 - 388.6 1 2 0 -0.0067 10 0 0 0 2.36E+07 2.38E+07 - - - 3.5855 0.9949 230117_WJC_METTL3_WT_vs_EV_F02.19019.19019.2 0.208 18-Jun K.LLLGDLAPVR[166.11].G sp|Q9NUQ8|ABCF3_HUMAN 1 1075.6629 6.6 15024 19019 2 1075.664908 538.8387 ATP-binding cassette sub-family F member 3 OS=Homo sapiens OX=9606 GN=ABCF3 PE=1 SV=2 5.84 3630.1 - 557901 - - - 1.8668 - 1.157 0.229 - 72.8 2 2 0 0.002 10 0 0 0 2.22E+07 3.37E+06 - - - 1.0044 1 230117_WJC_METTL3_WT_vs_EV_F02.19020.19020.2 1.01E-08 26-Dec R.FIAVGYVDDTQFVR.F "sp|P04439|HLAA_HUMAN,tr|A0A140T953|A0A140T953_HUMAN,tr|A0A140T941|A0A140T941_HUMAN,tr|A0A1W2PQS8|A0A1W2PQS8_HUMAN,tr|A0A0G2JI36|A0A0G2JI36_HUMAN,tr|A0A140T8W8|A0A140T8W8_HUMAN,tr|Q9GJ45|Q9GJ45_HUMAN,tr|Q53Z42|Q53Z42_HUMAN,tr|Q5RJ27|Q5RJ27_HUMAN,tr|Q53YP1|Q53YP1_HUMAN,tr|Q5SRN5|Q5SRN5_HUMAN,tr|A0A1W2PS24|A0A1W2PS24_HUMAN,tr|A0A0G2JIF2|A0A0G2JIF2_HUMAN,tr|A0A1W2PQD0|A0A1W2PQD0_HUMAN,tr|A0A1W2PRZ0|A0A1W2PRZ0_HUMAN,tr|A0A140T9U0|A0A140T9U0_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A0G2JPD3|A0A0G2JPD3_HUMAN,tr|A0A140T9W2|A0A140T9W2_HUMAN,tr|O78179|O78179_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|A0A1W2PPQ2|A0A1W2PPQ2_HUMAN,tr|A0A140T9T1|A0A140T9T1_HUMAN,tr|Q5SPM2|Q5SPM2_HUMAN,tr|Q5SUL5|Q5SUL5_HUMAN,tr|A0A140T8Y4|A0A140T8Y4_HUMAN,tr|A0A140T975|A0A140T975_HUMAN,tr|A0A140TA03|A0A140TA03_HUMAN,tr|A0A140TA13|A0A140TA13_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A1W2PSE7|A0A1W2PSE7_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|A0A1W2PPF8|A0A1W2PPF8_HUMAN,tr|D9J307|D9J307_HUMAN,tr|A0A140T937|A0A140T937_HUMAN,tr|Q5SRN7|Q5SRN7_HUMAN,tr|A0A1W2PR61|A0A1W2PR61_HUMAN,tr|A0A140T912|A0A140T912_HUMAN,tr|A0A140T9M0|A0A140T9M0_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN,tr|A0A1W2PS39|A0A1W2PS39_HUMAN,tr|A0A140T9Z6|A0A140T9Z6_HUMAN,tr|A0A140T9M5|A0A140T9M5_HUMAN,tr|A0A140T930|A0A140T930_HUMAN,tr|A0A140T9Z4|A0A140T9Z4_HUMAN,tr|B0UXQ0|B0UXQ0_HUMAN,tr|A0A0G2JL56|A0A0G2JL56_HUMAN" 48 1628.8199 2.97 15025 19020 2 1628.824739 815.4172 "HLA class I histocompatibility antigen, A alpha chain OS=Homo sapiens OX=9606 GN=HLA-A PE=1 SV=2" 4.21 3630.3 - 303786 - - - 2.9966 - 2.728 0.676 - 462.3 1 2 0 0.0049 14 0 0 0 4.67E+06 1.57E+06 - - - 6.5508 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.19021.19021.2 0.0979 12-Jun K.LGDLFFR.V "sp|Q70EL1|UBP54_HUMAN,tr|H7C1E9|H7C1E9_HUMAN,tr|A0A7P0T9N2|A0A7P0T9N2_HUMAN,tr|A0A7P0T9K1|A0A7P0T9K1_HUMAN,tr|A0A804D9U3|A0A804D9U3_HUMAN" 5 866.465 1.61 15026 19021 2 866.466984 434.2398 Inactive ubiquitin carboxyl-terminal hydrolase 54 OS=Homo sapiens OX=9606 GN=USP54 PE=1 SV=4 5.84 3630.4 - 189403 - - - 2.2459 - 1.452 0.197 - 84.9 1 2 0 0.0019 7 0 0 0 2.12E+06 1.32E+06 - - - 1.6771 1 230117_WJC_METTL3_WT_vs_EV_F02.19023.19023.2 1.31E-05 13/20 K.MALDIEIATYR[166.11].K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1304.6674 1.5 15027 19023 2 1304.67045 653.341 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3630.6 - 7.64E+06 - - - 2.3431 - 2.78 0.513 - 792.2 1 2 0 0.0031 11 0 0 0 2.05E+08 1.37E+08 - - - 5.595 1 230117_WJC_METTL3_WT_vs_EV_F02.19028.19028.2 1.63E-05 18-Oct K.GIFLGDDEWR[166.11].E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1216.5752 1.67 15031 19028 2 1216.575307 609.2949 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3631.2 - 555728 - - - 0.0822 - 1.998 0.581 - 336.2 1 2 0 0.0001 10 0 0 0 2.59E+07 1.56E+07 - - - 5.2642 1 230117_WJC_METTL3_WT_vs_EV_F02.19033.19033.2 2.53E-05 18-Oct K.GIFLGDDEWR.E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1206.5669 1.67 15034 19033 2 1206.566857 604.2907 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3631.9 - 609595 - - - -0.0663 - 2.159 0.552 - 337 1 2 0 -0.0001 10 0 0 0 2.59E+07 1.56E+07 - - - 5.2664 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.19035.19035.2 0.13 16-Jun K.VQWGVFVPR.D sp|Q8IWA0|WDR75_HUMAN 1 1086.5974 1.34 15036 19035 2 1086.599393 544.306 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 9.72 3632.1 - 657232 - - - 1.7882 - 1.36 0.209 - 102.8 1 2 0 0.0019 9 0 0 0 2.02E+07 1.50E+07 - - - 1.4736 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.19036.19036.2 0.116 14-Sep K.LLQQLFLK[136.11].A sp|Q9P287|BCCIP_HUMAN 1 1009.6416 1.4 15037 19036 2 1009.64401 505.8281 BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1 8.75 3632.2 - 637212 - - - 2.4335 - 1.701 0.202 - 166 1 2 0 0.0025 8 0 0 0 2.95E+07 2.11E+07 - - - 2.1343 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.19038.19038.2 0.573 18-Oct R.LLLDTLQLSK[136.11].- "sp|O15357|SHIP2_HUMAN,tr|H7BXR2|H7BXR2_HUMAN" 2 1150.7053 2.64 15039 19038 2 1150.706914 576.3599 "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 OS=Homo sapiens OX=9606 GN=INPPL1 PE=1 SV=2" 5.84 3632.4 - 234413 - - - 1.4243 - 1.779 0.203 - 201.5 1 2 0 0.0016 10 0 0 0 1.12E+07 4.23E+06 - - - 2.1478 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.19043.19043.2 0.15 14-Aug K.LLQQLFLK.A sp|Q9P287|BCCIP_HUMAN 1 1001.6274 1.39 15042 19043 2 1001.631035 501.821 BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1 8.75 3633.1 - 1.14E+06 - - - 3.676 - 1.665 0.25 - 165.4 1 2 0 0.0037 8 0 0 0 2.95E+07 2.12E+07 - - - 2.424 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19044.19044.2 7.92E-05 16-Oct K.ASSLISLLK.Q "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 930.575 2.51 15043 19044 2 930.578044 466.2948 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.8 3633.2 - 939172 - - - 3.2894 - 2.01 0.42 - 363.1 1 2 0 0.0031 9 0 0 0 3.34E+07 1.33E+07 - - - 4.1619 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19045.19045.2 0.000606 16-Aug K.FALNSLLQR.Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1060.6029 2.21 15044 19045 2 1060.604122 531.3087 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.75 3633.3 - 1.10E+06 - - - 1.1248 - 1.832 0.41 - 205.2 1 2 0 0.0012 9 0 0 0 4.34E+07 1.96E+07 - - - 3.8204 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.19048.19048.2 0.00459 22-Aug K.TPLPPELADVQA.- "sp|Q9Y5V0|ZN706_HUMAN,tr|H0YC70|H0YC70_HUMAN" 2 1249.6554 - 15047 19048 2 1249.660578 625.835 Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1 3.67 3633.7 - 307502 - - - 4.1291 - 1.492 0.372 - 161 1 2 0 0.0052 12 0 0 0 - - - - - 2.8397 0.9891 230117_WJC_METTL3_WT_vs_EV_F02.19054.19054.2 0.138 18-Sep K.C[160.03]LEEFELLGK[136.11].A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1244.6202 1.02 15052 19054 2 1244.618292 623.3174 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3634.4 - 362539 - - - -1.5531 - 1.148 0.27 - 141.9 1 2 0 -0.0019 10 0 0 0 1.31E+07 1.29E+07 - - - 1.4199 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19055.19055.2 0.000301 18-Dec R.LMALLGQALK[136.11].W sp|Q2TAY7|SMU1_HUMAN 1 1064.6507 0.88 15053 19055 2 1064.653724 533.3326 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.75 3634.5 - 1.65E+06 - - - 2.8056 - 2.135 0.35 - 465.2 1 2 0 0.003 10 0 0 0 3.76E+07 4.26E+07 - - - 3.7423 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19056.19056.2 0.0158 14-Aug R.LSFAVPFR.E sp|P78527|PRKDC_HUMAN 1 935.5229 1.15 15054 19056 2 935.524933 468.7687 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3634.5 - 1.58E+06 - - - 2.1859 - 1.961 0.277 - 202 1 2 0 0.002 8 0 0 0 2.61E+07 2.26E+07 - - - 3.1174 1 230117_WJC_METTL3_WT_vs_EV_F02.19057.19057.2 4.43E-07 16-Nov K.VFDAIMNFK.K sp|P13639|EF2_HUMAN 1 1083.5423 3.72 15055 19057 2 1083.545216 542.7784 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.81 3634.6 - 1.56E+06 - - - 2.6884 - 1.991 0.557 - 356 1 2 0 0.0029 9 0 0 0 7.49E+07 2.01E+07 - - - 5.1464 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.19058.19058.2 0.00187 14-Oct R.LSFAVPFR[166.11].E sp|P78527|PRKDC_HUMAN 1 945.5312 1.15 15056 19058 2 945.53386 473.7729 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3634.7 - 1.54E+06 - - - 2.8577 - 1.899 0.351 - 362.5 1 2 0 0.0027 8 0 0 0 2.60E+07 2.25E+07 - - - 3.5669 0.997 230117_WJC_METTL3_WT_vs_EV_F02.19059.19059.2 0.128 16-Sep K.IIDGLLVMR[166.11].K "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1038.6135 3.27 15057 19059 2 1038.617712 520.314 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.84 3634.8 - 882662 - - - 4.0487 - 1.892 0.231 - 199.8 1 2 0 0.0042 9 0 0 0 1.06E+08 3.25E+07 - - - 2.5906 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.19060.19060.2 0.00211 16-Oct K.FALNSLLQR[166.11].Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1070.6112 2.35 15058 19060 2 1070.614721 536.3129 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.75 3634.9 - 818760 - - - 3.2897 - 1.963 0.422 - 410.1 1 2 0 0.0035 9 0 0 0 4.30E+07 1.83E+07 - - - 4.1081 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.19067.19067.2 0.0647 12-Jun R.EYLYFLK.H sp|Q8N1N4|K2C78_HUMAN 1 974.5113 23.32 15063 19067 2 974.512454 488.2629 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 6.1 3635.8 - 1.91E+06 - - - 1.1637 - 1.231 0.348 - 122.9 1 2 0 0.0011 7 0 0 0 4.25E+07 1.82E+06 - - - 2.2695 0.999 230117_WJC_METTL3_WT_vs_EV_F02.19074.19074.2 0.00649 18-Oct R.LFDQAFGLPR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1162.6135 1.18 15069 19074 2 1162.61814 582.314 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3636.7 - 2.31E+07 - - - 3.9962 - 2.113 0.417 - 493.7 1 2 0 0.0046 10 0 0 0 3.56E+08 3.02E+08 - - - 4.2077 0.9938 230117_WJC_METTL3_WT_vs_EV_F02.19079.19079.2 0.208 14-Jun R.IPLNDLFR.C sp|P13473|LAMP2_HUMAN 1 986.5549 5.35 15073 19079 2 986.558178 494.2847 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3637.3 - 578556 - - - 3.3065 - 1.471 0.166 - 115.6 1 2 0 0.0033 8 0 0 0 7.72E+07 1.44E+07 - - - 1.43 0.9933 230117_WJC_METTL3_WT_vs_EV_F02.19081.19081.3 0.0401 Jul-36 K.SAEFLLHMLK[136.11].N "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 1195.6515 0.85 15075 19081 3 1195.656476 399.5578 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 6.47 3637.6 - 217231 - - - 4.1902 - 1.492 0.27 - 61 1 2 0 0.005 10 0 0 0 1.86E+06 2.19E+06 - - - 2.7174 0.997 230117_WJC_METTL3_WT_vs_EV_F02.19083.19083.3 0.00697 Sep-36 R.LFDQAFGLPR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1162.6135 0.8 15077 19083 3 1162.617469 388.5451 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3637.8 - 151356 - - - 3.419 - 1.322 0.321 - 88.1 1 2 0 0.004 10 0 0 0 2.15E+06 2.69E+06 - - - 2.933 0.999 230117_WJC_METTL3_WT_vs_EV_F02.19088.19088.2 0.00156 16-Aug K.VFDAIMNFK[136.11].K sp|P13639|EF2_HUMAN 1 1091.5565 3.69 15080 19088 2 1091.55577 546.7855 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.81 3638.5 - 1.46E+06 - - - -0.6715 - 1.669 0.38 - 124.8 1 2 0 -0.0007 9 0 0 0 7.43E+07 2.01E+07 - - - 3.3293 0.9965 230117_WJC_METTL3_WT_vs_EV_F02.19089.19089.2 0.0486 16-Jul K.ASSLISLLK[136.11].Q "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 938.5892 2.47 15081 19089 2 938.590665 470.3019 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.8 3638.6 - 1.06E+06 - - - 1.579 - 1.448 0.174 - 81.1 2 2 0 0.0015 9 0 0 0 3.27E+07 1.32E+07 - - - 1.2622 0.9929 230117_WJC_METTL3_WT_vs_EV_F02.19093.19093.3 0.00034 Oct-36 K.FLPFSFEHIR[166.11].E "sp|Q93050|VPP1_HUMAN,tr|F5H1T6|F5H1T6_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 4 1301.6796 1.36 15085 19093 3 1301.689049 434.9005 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 6.75 3639.1 - 127707 - - - 7.2491 - 1.784 0.374 - 116 1 2 0 0.0094 10 0 0 0 2.43E+06 1.79E+06 - - - 4.3976 0.9847 230117_WJC_METTL3_WT_vs_EV_F02.19094.19094.2 0.0104 22-Aug K.GALPLDTVTFYK.V sp|P30040|ERP29_HUMAN 1 1323.7075 1.49 15086 19094 2 1323.714829 662.861 Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4 5.83 3639.3 - 123444 - - - 5.5715 - 1.539 0.245 - 113.5 1 2 0 0.0074 12 0 0 0 4.61E+06 3.09E+06 - - - 1.9826 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19098.19098.2 0.000329 16-Oct K.SGILPILVK.C sp|O00505|IMA4_HUMAN 1 938.6165 1.25 15088 19098 2 938.619071 470.3155 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3639.8 - 2.39E+06 - - - 2.7881 - 1.971 0.417 - 220.7 1 2 0 0.0026 9 0 0 0 2.79E+07 2.23E+07 - - - 4.0832 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.19099.19099.2 0.0418 16-Sep K.SGILPILVK[136.11].C sp|O00505|IMA4_HUMAN 1 946.6307 1.25 15089 19099 2 946.632489 474.3226 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3639.9 - 2.27E+06 - - - 1.9385 - 1.319 0.34 - 151.2 1 2 0 0.0018 9 0 0 0 2.79E+07 2.23E+07 - - - 2.3527 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.19100.19100.2 1.71E-05 16-Oct K.MC[160.03]LFAGFQR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1128.5209 0.87 15090 19100 2 1128.526495 565.2677 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3640 - 3.22E+06 - - - 4.9968 - 2.052 0.357 - 604.7 1 2 0 0.0056 9 0 0 0 5.40E+07 6.19E+07 - - - 3.7556 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.19102.19102.2 0.0447 14-Aug R.LLASFFDR.N sp|Q96RE7|NACC1_HUMAN 1 967.5127 2.2 15092 19102 2 967.516841 484.7636 Nucleus accumbens-associated protein 1 OS=Homo sapiens OX=9606 GN=NACC1 PE=1 SV=1 5.84 3640.3 - 681546 - - - 4.2625 - 1.724 0.235 - 161.1 1 2 0 0.0041 8 0 0 0 7.14E+06 3.25E+06 - - - 2.418 0.9519 230117_WJC_METTL3_WT_vs_EV_F02.19103.19103.2 0.378 16-Jul K.GLSLGFLEK.K sp|Q9NU22|MDN1_HUMAN 1 962.5437 0.31 15093 19103 2 962.548014 482.2791 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6 3640.4 - 569759 - - - 4.4995 - 1.533 0.026 - 107.8 1 2 0 0.0043 9 0 0 0 7.33E+06 2.35E+07 - - - 0.4677 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19105.19105.3 0.000686 Oct-36 K.FLPFSFEHIR.E "sp|Q93050|VPP1_HUMAN,tr|F5H1T6|F5H1T6_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 4 1291.6713 1.36 15095 19105 3 1291.676392 431.5644 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 6.75 3640.6 - 282298 - - - 3.9089 - 1.649 0.392 - 114.4 1 2 0 0.005 10 0 0 0 2.43E+06 1.79E+06 - - - 4.3697 0.9793 230117_WJC_METTL3_WT_vs_EV_F02.19108.19108.2 0.31 16-Jun R.LTAILLQIK.C "sp|Q5TKA1|LIN9_HUMAN,tr|C9J5J4|C9J5J4_HUMAN,tr|H0Y322|H0Y322_HUMAN,tr|H7C4T7|H7C4T7_HUMAN" 4 1011.6692 2.2 15098 19108 2 1011.673703 506.8419 Protein lin-9 homolog OS=Homo sapiens OX=9606 GN=LIN9 PE=1 SV=1 8.75 3641 - 224794 - - - 4.4333 - 1.367 0.194 - 52.9 5 2 0 0.0045 9 0 0 0 1.84E+06 8.38E+05 - - - 1.0647 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.19113.19113.2 1.13E-05 16-Oct K.MC[160.03]LFAGFQR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1138.5291 0.87 15102 19113 2 1138.535038 570.2718 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3641.7 - 6.13E+06 - - - 5.1927 - 1.962 0.344 - 602.9 1 2 0 0.0059 9 0 0 0 5.40E+07 6.19E+07 - - - 3.5297 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19114.19114.2 0.0004 18-Nov R.LEPVIMELER[166.11].Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1237.6616 0.55 15103 19114 2 1237.665687 619.8381 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3641.8 - 6.04E+06 - - - 3.3184 - 1.999 0.446 - 483.2 1 2 0 0.0041 10 0 0 0 4.45E+07 8.11E+07 - - - 4.2673 0.998 230117_WJC_METTL3_WT_vs_EV_F02.19120.19120.2 0.164 16-Jul R.LQLPVWEYK[136.11].D sp|O43143|DHX15_HUMAN 1 1182.6528 2.97 15109 19120 2 1182.65608 592.3337 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 3642.3 - 1.58E+06 - - - 2.7345 - 1.488 0.263 - 170.6 1 2 0 0.0032 9 0 0 0 8.83E+07 2.98E+07 - - - 2.1323 0.9952 230117_WJC_METTL3_WT_vs_EV_F02.19121.19121.2 0.000554 18-Sep K.SVPDEIILLR.S sp|Q9H9A6|LRC40_HUMAN 1 1153.6707 2.25 15110 19121 2 1153.677806 577.8426 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.37 3642.4 - 1.41E+06 - - - 6.182 - 1.913 0.433 - 368.2 1 2 0 0.0071 10 0 0 0 2.48E+07 1.10E+07 - - - 4.0475 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.19125.19125.2 0.00512 20-Dec K.MALDIEIATYR.K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1294.6591 1.5 15114 19125 2 1294.664056 648.3368 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3642.9 - 1.03E+06 - - - 3.8103 - 2.42 0.381 - 620.5 1 2 0 0.0049 11 0 0 0 2.05E+08 1.36E+08 - - - 4.2443 0.9923 230117_WJC_METTL3_WT_vs_EV_F02.19127.19127.2 0.107 18-Sep K.TIC[160.03]AEFAILR[166.11].M "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1202.6357 1.24 15116 19127 2 1202.636346 602.3251 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.66 3643.1 - 593846 - - - 0.538 - 1.304 0.132 - 154.1 1 2 0 0.0006 10 0 0 0 2.32E+07 1.87E+07 - - - 0.7567 0.9963 230117_WJC_METTL3_WT_vs_EV_F02.19129.19129.2 0.787 14-Aug R.VLLLPLER.D sp|O95071|UBR5_HUMAN 1 951.6117 1.73 15118 19129 2 951.614406 476.8131 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3643.3 - 492328 - - - 2.8404 - 1.631 0.149 - 227.8 1 2 0 0.0027 8 0 0 0 1.57E+07 9.08E+06 - - - 1.616 0.9475 230117_WJC_METTL3_WT_vs_EV_F02.19136.19136.2 0.062 16-Nov S.GDLLSEVER.N "sp|O14513|NCKP5_HUMAN,tr|A0A0A0MSE4|A0A0A0MSE4_HUMAN,tr|A0A0A0MS79|A0A0A0MS79_HUMAN" 3 1016.5138 10.64 15124 19136 2 1016.517073 509.2642 Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=2 4.14 3644.2 - 2.70E+06 - - - 3.1815 - 2.128 0.356 - 545.3 1 1 0 0.0032 9 0 0 0 7.07E+07 6.64E+06 - - - 3.8542 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.19137.19137.2 0.686 14-Jul R.VLLLPLER[166.11].D sp|O95071|UBR5_HUMAN 1 961.62 1.51 15125 19137 2 961.622126 481.8173 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3644.3 - 1.61E+06 - - - 2.2389 - 1.556 0.257 - 163.7 1 2 0 0.0022 8 0 0 0 1.58E+07 1.04E+07 - - - 2.2719 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19140.19140.2 0.011 24-Dec R.ALGLGLVSPAQLR.V "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|A8MRA7|A8MRA7_HUMAN" 3 1293.7769 2.91 15128 19140 2 1293.778996 647.8957 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 9.79 3644.6 - 626773 - - - 1.6425 - 2.627 0.312 - 553.1 1 2 0 0.0021 13 0 0 0 6.28E+06 2.16E+06 - - - 3.8236 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19141.19141.2 0.0003 22-Nov K.GALPLDTVTFYK[136.11].V sp|P30040|ERP29_HUMAN 1 1331.7217 1.53 15129 19141 2 1331.722683 666.8681 Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4 5.83 3644.7 - 549626 - - - 0.7727 - 2.171 0.226 - 372.5 1 2 0 0.001 12 0 0 0 4.61E+06 3.02E+06 - - - 2.7496 1 230117_WJC_METTL3_WT_vs_EV_F02.19144.19144.2 7.84E-06 24-Nov R.LLPGEEC[160.03]VLDGLR.V sp|O95248|MTMR5_HUMAN 1 1469.7548 1.46 15132 19144 2 1469.753061 735.8847 Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4 4.14 3645.1 - 201140 - - - -1.1934 - 2.246 0.552 - 394.6 1 2 0 -0.0018 13 0 0 0 2.94E+06 2.02E+06 - - - 5.1942 0.9433 230117_WJC_METTL3_WT_vs_EV_F02.19148.19148.2 0.203 14-Jul R.FYTIEILK.V sp|P12273|PIP_HUMAN 1 1025.5797 175.54 15135 19148 2 1025.582734 513.7971 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 6 3645.6 - 3.25E+06 - - - 2.9252 - 1.174 0.02 - 135.1 1 2 0 0.003 8 0 0 0 3.56E+08 2.03E+06 - - - -0.3284 0.999 230117_WJC_METTL3_WT_vs_EV_F02.19149.19149.2 0.00104 20-Sep R.FLMSLVNQVPK.L "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 1274.7057 1 15136 19149 2 1274.709729 638.3601 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 8.75 3645.8 - 1.01E+06 - - - 3.1764 - 1.864 0.334 - 241.5 1 2 0 0.004 11 0 0 0 4.94E+07 4.94E+07 - - - 3.1913 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19150.19150.2 0.0357 14-Aug K.MIDLIIPR.G sp|P54886|P5CS_HUMAN 1 969.5681 1.59 15137 19150 2 969.570861 485.7913 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 5.59 3645.8 - 2.07E+06 - - - 2.8239 - 1.745 0.341 - 252.9 1 2 0 0.0027 8 0 0 0 7.82E+06 4.93E+06 - - - 3.2379 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.19152.19152.2 1.48 14-Jul K.MIDLIIPR[166.11].G sp|P54886|P5CS_HUMAN 1 979.5764 1.63 15139 19152 2 979.579667 490.7955 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 5.59 3646 - 1.14E+06 - - - 3.3423 - 1.554 0.275 - 167.8 1 2 0 0.0033 8 0 0 0 7.79E+06 4.79E+06 - - - 2.4007 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.19153.19153.2 0.0121 24-Nov K.FIAELGVPLSQVK.S sp|Q86T24|KAISO_HUMAN 1 1399.8075 5.66 15140 19153 2 1399.812204 700.911 Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2 6 3646.1 - 797070 - - - 3.359 - 1.937 0.376 - 317.5 1 2 0 0.0047 13 0 0 0 2.97E+06 5.25E+05 - - - 3.5135 1 230117_WJC_METTL3_WT_vs_EV_F02.19155.19155.2 0.000888 24-Nov R.LLPGEEC[160.03]VLDGLR[166.11].V sp|O95248|MTMR5_HUMAN 1 1479.7631 1.46 15142 19155 2 1479.76761 740.8888 Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4 4.14 3646.3 - 685750 - - - 3.0579 - 2.164 0.514 - 378.4 1 2 0 0.0045 13 0 0 0 2.94E+06 2.02E+06 - - - 4.8172 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19156.19156.2 4.89E-05 Dec-32 R.AAVEEGIVLGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1683.8978 -1 15143 19156 2 1683.90185 842.9562 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3646.5 - 503428 - - - 2.4105 - 2.453 0.326 - 371.4 1 2 0 0.0041 17 0 0 0 0.00E+00 0.00E+00 - - - 3.6536 0.9922 230117_WJC_METTL3_WT_vs_EV_F02.19159.19159.2 0.757 20-Jun K.LFGALTPLEPR[166.11].L "sp|O14617|AP3D1_HUMAN,tr|A0A087WYN6|A0A087WYN6_HUMAN,tr|A0A2R8Y4J3|A0A2R8Y4J3_HUMAN" 3 1222.6949 2.88 15146 19159 2 1222.699809 612.3547 AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1 6 3646.9 - 292195 - - - 3.9912 - 1.442 0.244 - 63.9 3 2 0 0.0049 11 0 0 0 6.89E+06 2.39E+06 - - - 1.6187 0.9871 230117_WJC_METTL3_WT_vs_EV_F02.19161.19161.2 0.484 14-Jun K.GLLDVLPK.N "sp|O95071|UBR5_HUMAN,tr|E7ET84|E7ET84_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 853.5273 5.37 15148 19161 2 853.529875 427.7709 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.84 3647.1 - 255108 - - - 3.0122 - 1.178 0.19 - 83.7 3 2 0 0.0026 8 0 0 0 1.14E+06 2.13E+05 - - - 0.7245 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.19162.19162.2 0.00179 Sep-32 R.AAVEEGIVLGGGC[160.03]ALLR[166.11].C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1693.9061 -1 15149 19162 2 1693.90989 847.9603 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3647.2 - 161914 - - - 2.2605 - 1.649 0.384 - 112 1 2 0 0.0038 17 0 0 0 0.00E+00 0.00E+00 - - - 3.1057 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19164.19164.2 0.00585 18-Sep R.LEPVIMELER.Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1227.6533 0.54 15150 19164 2 1227.656026 614.8339 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3647.5 - 1.37E+06 - - - 2.2124 - 1.913 0.378 - 347.7 1 2 0 0.0027 10 0 0 0 4.32E+07 7.99E+07 - - - 3.6427 0.9791 230117_WJC_METTL3_WT_vs_EV_F02.19166.19166.2 0.0136 12-Aug R.IQLLVFK[136.11].H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 867.5673 0.68 15151 19166 2 867.572612 434.7909 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3647.7 - 1.76E+06 - - - 6.0941 - 1.89 0.13 - 217.9 1 2 0 0.0053 7 0 0 0 1.78E+07 2.61E+07 - - - 2.0165 0.9597 230117_WJC_METTL3_WT_vs_EV_F02.19167.19167.2 0.00397 12-Aug R.IQLLVFK.H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 859.5531 0.68 15152 19167 2 859.558664 430.7838 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3647.8 - 1.07E+06 - - - 6.444 - 1.707 0.119 - 213.1 1 2 0 0.0055 7 0 0 0 1.78E+07 2.61E+07 - - - 1.6125 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.19168.19168.2 0.00663 14-Aug K.ILTPIIFK.E "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5L9|H7C5L9_HUMAN" 4 943.6106 0.83 15153 19168 2 943.612912 472.8126 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 8.75 3647.9 - 1.17E+06 - - - 2.4078 - 1.592 0.378 - 164.7 1 2 0 0.0023 8 0 0 0 9.65E+06 1.16E+07 - - - 3.2346 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19169.19169.2 0.0148 18-Sep R.AVLDALLEGK[136.11].A "sp|P46821|MAP1B_HUMAN,sp|P78559|MAP1A_HUMAN,tr|E9PGC8|E9PGC8_HUMAN" 3 1035.6056 2.12 15154 19169 2 1035.60598 518.8101 Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2 4.37 3647.9 - 1.04E+06 - - - 0.4046 - 1.865 0.285 - 223.5 1 2 0 0.0004 10 0 0 0 7.10E+07 3.35E+07 - - - 2.8856 1 230117_WJC_METTL3_WT_vs_EV_F02.19171.19171.2 3.59E-05 15/22 K.LSTIALALGVER[166.11].T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1251.7426 2.23 15156 19171 2 1251.745922 626.8786 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3648.1 - 730732 - - - 2.6483 - 2.773 0.442 - 921.1 1 2 0 0.0033 12 0 0 0 3.49E+07 1.56E+07 - - - 4.9882 1 230117_WJC_METTL3_WT_vs_EV_F02.19173.19173.2 9.14E-08 20-Nov R.FSTIEEFSYIR.R "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1390.6769 1.28 15158 19173 2 1390.685329 696.3457 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 4.53 3648.3 - 635408 - - - 6.074 - 2.41 0.57 - 507.7 1 2 0 0.0084 11 0 0 0 2.89E+06 2.25E+06 - - - 5.628 1 230117_WJC_METTL3_WT_vs_EV_F02.19174.19174.2 1.51E-07 20-Nov R.FSTIEEFSYIR[166.11].R "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1400.6852 1.28 15159 19174 2 1400.690106 701.3499 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 4.53 3648.4 - 570858 - - - 3.5368 - 2.243 0.544 - 403.3 1 2 0 0.005 11 0 0 0 2.89E+06 2.25E+06 - - - 5.2428 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19175.19175.2 7.17E-05 20-Dec K.ELFPIQMEGVK.L "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 1289.669 0.79 15160 19175 2 1289.673669 645.8418 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.53 3648.5 - 567167 - - - 3.6513 - 1.966 0.44 - 433.1 1 2 0 0.0047 11 0 0 0 4.36E+06 5.52E+06 - - - 4.1181 1 230117_WJC_METTL3_WT_vs_EV_F02.19176.19176.2 0.00672 13/20 K.LLEVQILEVQR.A "sp|Q8IWJ2|GCC2_HUMAN,tr|H7BYJ9|H7BYJ9_HUMAN" 2 1338.7871 1.59 15161 19176 2 1338.792455 670.4008 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.53 3648.6 - 539089 - - - 3.9991 - 2.573 0.517 - 807.1 1 2 0 0.0054 11 0 0 0 3.38E+06 2.13E+06 - - - 5.4145 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19177.19177.2 0.103 20-Nov K.GPILMELQTYR.Y "sp|P08559|ODPA_HUMAN,sp|P29803|ODPAT_HUMAN" 2 1319.6908 2.52 15162 19177 2 1319.69505 660.8527 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 6 3648.8 - 531247 - - - 3.2523 - 2.188 0.45 - 460.5 1 2 0 0.0043 11 0 0 0 3.02E+06 1.20E+06 - - - 4.4815 1 230117_WJC_METTL3_WT_vs_EV_F02.19180.19180.2 2.42E-05 20-Dec K.LLEVQILEVQR[166.11].A "sp|Q8IWJ2|GCC2_HUMAN,tr|H7BYJ9|H7BYJ9_HUMAN" 2 1348.7954 1.59 15165 19180 2 1348.799333 675.405 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.53 3649.1 - 357064 - - - 2.9374 - 2.247 0.464 - 509.7 1 2 0 0.004 11 0 0 0 3.38E+06 2.13E+06 - - - 4.657 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.19181.19181.2 0.0237 20-Aug K.ELFPIQMEGVK[136.11].L "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 1297.6832 0.79 15166 19181 2 1297.686074 649.8489 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.53 3649.2 - 356516 - - - 2.2455 - 1.72 0.271 - 151.4 1 2 0 0.0029 11 0 0 0 4.36E+06 5.52E+06 - - - 2.5088 0.991 230117_WJC_METTL3_WT_vs_EV_F02.19182.19182.2 0.0858 20-Aug K.LIDFGSGALLK.D "sp|P11309|PIM1_HUMAN,sp|Q86V86|PIM3_HUMAN" 2 1132.6492 0.04 15167 19182 2 1132.653983 567.3319 Serine\threonine-protein kinase pim-1 OS=Homo sapiens OX=9606 GN=PIM1 PE=1 SV=4 5.84 3649.3 - 339907 - - - 4.2131 - 1.343 0.242 - 102.6 1 2 0 0.0048 11 0 0 0 1.74E+06 4.01E+07 - - - 1.6247 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.19189.19189.2 0.000246 15/22 K.LSTIALALGVER.T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1241.7343 2.22 15173 19189 2 1241.740813 621.8744 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3650.1 - 3.44E+06 - - - 5.2153 - 2.655 0.396 - 846.3 1 2 0 0.0065 12 0 0 0 3.47E+07 1.56E+07 - - - 4.533 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.19190.19190.2 0.0427 16-Sep K.EAEILEVLR[166.11].H sp|P36551|HEM6_HUMAN 1 1080.6054 1.1 15174 19190 2 1080.608956 541.31 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.25 3650.2 - 1.81E+06 - - - 3.2491 - 1.979 0.285 - 256.2 1 2 0 0.0035 9 0 0 0 1.14E+07 1.04E+07 - - - 3.1197 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.19191.19191.2 0.00205 18-Oct R.IIVAIDGWPR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1148.6581 2.38 15175 19191 2 1148.663823 575.3364 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3650.3 - 1.70E+06 - - - 4.9397 - 2.045 0.363 - 303.5 1 2 0 0.0057 10 0 0 0 8.05E+07 3.38E+07 - - - 3.7172 0.999 230117_WJC_METTL3_WT_vs_EV_F02.19192.19192.2 0.0142 16-Aug K.LLIYWASTR.E sp|P06312|KV401_HUMAN 1 1121.6233 34.47 15176 19192 2 1121.627201 561.8189 Immunoglobulin kappa variable 4-1 OS=Homo sapiens OX=9606 GN=IGKV4-1 PE=1 SV=1 8.75 3650.4 - 1.43E+06 - - - 3.4512 - 1.847 0.359 - 210.6 1 2 0 0.0039 9 0 0 0 4.48E+07 1.30E+06 - - - 3.4664 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.19194.19194.2 0.000465 18-Oct K.SVVTSIFGVK[136.11].N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1043.6106 1.85 15178 19194 2 1043.616434 522.8126 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3650.6 - 1.25E+06 - - - 5.5452 - 2.199 0.438 - 284.1 1 2 0 0.0058 10 0 0 0 3.27E+07 1.77E+07 - - - 4.4738 0.9925 230117_WJC_METTL3_WT_vs_EV_F02.19195.19195.2 0.27 14-Sep K.GLLQLQWK[136.11].Q sp|O94826|TOM70_HUMAN 1 992.5899 1.36 15179 19195 2 992.595032 497.3022 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.75 3650.8 - 1.19E+06 - - - 5.2187 - 1.698 0.247 - 238.5 1 2 0 0.0052 8 0 0 0 6.05E+06 4.44E+06 - - - 2.4605 0.9868 230117_WJC_METTL3_WT_vs_EV_F02.19198.19198.2 0.0609 12-Jul R.DYLQLLR[166.11].K sp|L0R6Q1|S35U4_HUMAN 1 929.521 1.87 15182 19198 2 929.526022 465.7678 SLC35A4 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=SLC35A4 PE=3 SV=1 5.84 3651.1 - 733428 - - - 5.4168 - 1.369 0.269 - 212.9 1 2 0 0.005 7 0 0 0 6.65E+06 3.55E+06 - - - 2.0214 0.9935 230117_WJC_METTL3_WT_vs_EV_F02.19199.19199.2 0.00116 18-Sep K.SVPDEIILLR[166.11].S sp|Q9H9A6|LRC40_HUMAN 1 1163.6789 2.24 15183 19199 2 1163.685068 582.8467 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.37 3651.3 - 520018 - - - 5.2626 - 1.529 0.33 - 195.8 1 2 0 0.0061 10 0 0 0 2.41E+07 1.07E+07 - - - 2.6617 0.9145 230117_WJC_METTL3_WT_vs_EV_F02.19203.19203.2 0.004 24-Jul R.SYEAVAAAAASVY.N sp|Q9BWF3|RBM4_HUMAN 1 1271.6034 - 15187 19203 2 1271.607393 636.809 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4 3651.8 - 312128 - - - 3.1535 - 1.622 0.37 - 129.2 1 1 0 0.004 13 0 0 0 - - - - - 3.0139 0.9919 230117_WJC_METTL3_WT_vs_EV_F02.19206.19206.3 0.291 Nov-44 K.LSTIALALGVER.T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1241.7343 1.74 15190 19206 3 1241.741701 414.9187 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3652.2 - 244744 - - - 5.9304 - 2.177 0.253 - 115.4 1 2 0 0.0074 12 0 0 0 1.63E+06 9.40E+05 - - - 3.515 0.965 230117_WJC_METTL3_WT_vs_EV_F02.19209.19209.2 0.233 14-Jul K.LAIVLFTK[136.11].E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 911.5935 1.75 15192 19209 2 911.598722 456.804 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3652.5 - 370372 - - - 5.6846 - 1.639 0.106 - 118.4 1 2 0 0.0052 8 0 0 0 3.63E+06 2.07E+06 - - - 1.3124 0.998 230117_WJC_METTL3_WT_vs_EV_F02.19210.19210.2 0.0847 18-Oct R.IIVAIDGWPR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1138.6499 2.39 15193 19210 2 1138.652939 570.3322 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3652.6 - 1.13E+07 - - - 2.6874 - 2.108 0.136 - 382.3 1 2 0 0.0031 10 0 0 0 8.02E+07 3.35E+07 - - - 2.1261 0.9952 230117_WJC_METTL3_WT_vs_EV_F02.19214.19214.2 0.234 14-Jul K.GLLQLQWK.Q sp|O94826|TOM70_HUMAN 1 984.5757 1.28 15197 19214 2 984.578684 493.2951 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.75 3652.9 - 1.14E+06 - - - 3.0795 - 1.248 0.245 - 106.2 1 2 0 0.003 8 0 0 0 6.18E+06 4.82E+06 - - - 1.5178 1 230117_WJC_METTL3_WT_vs_EV_F02.19217.19217.2 5.93E-05 16-Nov R.QINWTVLYR[166.11].R "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1201.6483 1.03 15200 19217 2 1201.648935 601.8314 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 8.75 3653.1 - 911806 - - - 0.5176 - 2.28 0.433 - 754.7 1 2 0 0.0006 9 0 0 0 4.06E+07 3.93E+07 - - - 4.6233 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.19218.19218.2 0.0704 18-Jul K.LLVLSALAEK.L sp|Q13395|TARB1_HUMAN 1 1055.659 1.41 15201 19218 2 1055.661621 528.8368 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6 3653.1 - 851881 - - - 2.4383 - 1.516 0.331 - 103.9 1 2 0 0.0026 10 0 0 0 4.65E+06 3.30E+06 - - - 2.6464 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.19219.19219.2 0.316 14-Aug K.LAIVLFTK.E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 903.5793 1.75 15202 19219 2 903.581187 452.7969 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3653.2 - 712450 - - - 2.0441 - 1.737 0.18 - 168.2 1 2 0 0.0018 8 0 0 0 3.63E+06 2.07E+06 - - - 2.0352 0.9915 230117_WJC_METTL3_WT_vs_EV_F02.19220.19220.2 1.16 18-Jun R.IIGYGLPFPK.N sp|Q9UDY4|DNJB4_HUMAN 1 1103.6379 5.89 15203 19220 2 1103.638641 552.8262 DnaJ homolog subfamily B member 4 OS=Homo sapiens OX=9606 GN=DNAJB4 PE=1 SV=1 8.59 3653.3 - 294925 - - - 0.6551 - 1.292 0.122 - 60.2 1 2 0 0.0007 10 0 0 0 2.68E+06 4.55E+05 - - - 0.657 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19222.19222.2 0.000448 20-Dec K.ILALASFEVEK.T sp|Q8WZA0|LZIC_HUMAN 1 1218.686 12.84 15205 19222 2 1218.687929 610.3503 Protein LZIC OS=Homo sapiens OX=9606 GN=LZIC PE=1 SV=1 4.53 3653.5 - 281948 - - - 1.5911 - 1.912 0.348 - 303.8 1 2 0 0.0019 11 0 0 0 3.36E+06 2.61E+05 - - - 3.3641 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.19226.19226.2 0.000393 16-Oct K.VFSIGPVFR[166.11].A sp|P14868|SYDC_HUMAN 1 1030.5839 1.14 15207 19226 2 1030.589186 516.2992 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3654.1 - 5.08E+06 - - - 5.1078 - 1.955 0.447 - 397.5 1 2 0 0.0053 9 0 0 0 4.13E+07 3.63E+07 - - - 4.2804 0.9898 230117_WJC_METTL3_WT_vs_EV_F02.19227.19227.2 0.00434 16-Sep K.VFSIGPVFR.A sp|P14868|SYDC_HUMAN 1 1020.5757 1.12 15208 19227 2 1020.582781 511.2951 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3654.2 - 5.03E+06 - - - 6.9853 - 1.761 0.393 - 315.6 1 2 0 0.0071 9 0 0 0 4.02E+07 3.59E+07 - - - 3.5786 1 230117_WJC_METTL3_WT_vs_EV_F02.19228.19228.2 3.34E-05 16-Nov R.QINWTVLYR.R "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1191.64 1.07 15209 19228 2 1191.646659 596.8273 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 8.75 3654.3 - 1.97E+06 - - - 5.552 - 2.366 0.502 - 759.6 1 2 0 0.0066 9 0 0 0 4.20E+07 3.93E+07 - - - 5.2382 0.9363 230117_WJC_METTL3_WT_vs_EV_F02.19232.19232.2 0.257 20-Jun K.LFGALTPLEPR.L "sp|O14617|AP3D1_HUMAN,tr|A0A087WYN6|A0A087WYN6_HUMAN,tr|A0A2R8Y4J3|A0A2R8Y4J3_HUMAN" 3 1212.6867 3.99 15213 19232 2 1212.681723 607.3506 AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1 6 3654.8 - 488806 - - - -4.0703 - 1.371 0.199 - 55.2 2 2 0 -0.0049 11 0 0 0 2.32E+06 5.81E+05 - - - 1.2284 1 230117_WJC_METTL3_WT_vs_EV_F02.19233.19233.2 4.50E-06 22-Oct R.LC[160.03]LTDEEVVFVR.L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1478.7439 5 15214 19233 2 1478.748241 740.3792 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3654.9 - 436522 - - - 2.9248 - 2.082 0.573 - 338.5 1 2 0 0.0043 12 0 0 0 6.73E+06 1.35E+06 - - - 5.2013 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.19234.19234.2 0.00237 18-Aug K.ELPEYYELIR[166.11].K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1333.6793 1.6 15215 19234 2 1333.685009 667.8469 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3655 - 290372 - - - 4.2521 - 1.627 0.358 - 298.7 1 2 0 0.0057 10 0 0 0 1.45E+07 9.02E+06 - - - 3.042 1 230117_WJC_METTL3_WT_vs_EV_F02.19236.19236.2 2.50E-06 22-Nov R.LC[160.03]LTDEEVVFVR[166.11].L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1488.7522 4.98 15217 19236 2 1488.759599 745.3834 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3655.3 - 179342 - - - 4.9793 - 2.317 0.537 - 521.1 1 2 0 0.0074 12 0 0 0 6.70E+06 1.35E+06 - - - 5.2159 0.9962 230117_WJC_METTL3_WT_vs_EV_F02.19244.19244.2 0.0377 18-Jul R.LWIANYSLPR[166.11].A sp|O43172|PRP4_HUMAN 1 1241.6796 3.12 15224 19244 2 1241.683748 621.8471 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3656.4 - 4.48E+06 - - - 3.3302 - 1.765 0.187 - 162.4 2 2 0 0.0041 10 0 0 0 1.04E+08 3.35E+07 - - - 1.8723 1 230117_WJC_METTL3_WT_vs_EV_F02.19246.19246.2 4.45E-06 16-Oct K.MDLVTYFGK.R sp|P09543|CN37_HUMAN 1 1072.5263 3.38 15226 19246 2 1072.530496 537.2704 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 5.59 3656.5 - 2.86E+06 - - - 3.8955 - 2.115 0.504 - 444.6 1 2 0 0.0042 9 0 0 0 1.31E+07 3.87E+06 - - - 4.9293 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.19247.19247.2 0.0008 18-Oct K.ELPEYYELIR.K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1323.6711 1.6 15227 19247 2 1323.675468 662.8428 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3656.7 - 1.84E+06 - - - 3.3241 - 1.688 0.412 - 381.9 1 2 0 0.0044 10 0 0 0 1.45E+07 9.02E+06 - - - 3.544 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.19248.19248.2 0.00184 16-Oct K.ISVNDFIIK[136.11].A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1055.6106 0.73 15228 19248 2 1055.614383 528.8126 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 3656.8 - 1.44E+06 - - - 3.5392 - 1.859 0.346 - 190.1 1 2 0 0.0037 9 0 0 0 9.28E+06 1.26E+07 - - - 3.3892 1 230117_WJC_METTL3_WT_vs_EV_F02.19249.19249.2 0.00915 20-Dec R.GVIFTEAFVAR.H sp|O94874|UFL1_HUMAN 1 1208.6554 1.84 15229 19249 2 1208.660849 605.335 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 6 3656.9 - 1.33E+06 - - - 4.5422 - 2.606 0.434 - 375.4 1 2 0 0.0055 11 0 0 0 7.67E+06 4.17E+06 - - - 4.8359 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19251.19251.2 0.000273 13/24 R.IPSPLGYAAIPIK[136.11].F sp|Q9Y3A4|RRP7A_HUMAN 1 1346.8053 1.41 15231 19251 2 1346.80614 674.4099 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 8.59 3657.2 - 488348 - - - 0.6059 - 2.012 0.432 - 267.9 1 2 0 0.0008 13 0 0 0 5.04E+07 3.57E+07 - - - 4.0258 0.9484 230117_WJC_METTL3_WT_vs_EV_F02.19256.19256.3 0.378 Sep-36 R.LWIANYSLPR.A sp|O43172|PRP4_HUMAN 1 1231.6713 3.41 15236 19256 3 1231.676346 411.5644 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3657.8 - 253084 - - - 4.062 - 1.432 0.146 - 110.1 1 2 0 0.005 10 0 0 0 1.88E+06 5.53E+05 - - - 1.215 0.9511 230117_WJC_METTL3_WT_vs_EV_F02.19257.19257.2 5.12E-05 24-Oct V.ALVMLQEDELLSK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1495.8047 1.5 15237 19257 2 1495.809803 748.9096 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3657.9 - 195256 - - - 3.3901 - 2.366 0.415 - 295.9 1 1 0 0.0051 13 0 0 0 3.68E+07 2.45E+07 - - - 4.3149 1 230117_WJC_METTL3_WT_vs_EV_F02.19262.19262.2 0.00263 26-Dec K.VLELDPALAPVVSR.E "sp|O00170|AIP_HUMAN,tr|A0A804HKK3|A0A804HKK3_HUMAN,tr|A0A804HKL7|A0A804HKL7_HUMAN,tr|A0A804HJ46|A0A804HJ46_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN" 6 1477.8504 5.23 15241 19262 2 1477.854929 739.9325 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 4.37 3658.5 - 2.22E+06 - - - 3.0443 - 2.597 0.459 - 276 1 2 0 0.0045 14 0 0 0 2.07E+07 3.96E+06 - - - 4.8247 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.19263.19263.2 0.00635 16-Sep K.ISVNDFIIK.A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1047.5964 0.74 15242 19263 2 1047.60105 524.8055 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 3658.6 - 2.08E+06 - - - 4.3939 - 1.699 0.336 - 142.4 1 2 0 0.0046 9 0 0 0 9.22E+06 1.24E+07 - - - 3.0547 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19264.19264.2 9.11E-05 18-Sep R.FFLSSGLIDK[136.11].V sp|Q9BTV4|TMM43_HUMAN 1 1133.6212 1 15243 19264 2 1133.622945 567.8179 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 5.84 3658.6 - 1.84E+06 - - - 1.5296 - 1.773 0.47 - 177.2 1 2 0 0.0017 10 0 0 0 1.12E+07 1.11E+07 - - - 4.1104 0.9527 230117_WJC_METTL3_WT_vs_EV_F02.19265.19265.2 1.89 12-Jun K.QFLDYFK.T "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 959.4753 1.4 15244 19265 2 959.478359 480.7449 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.83 3658.8 - 1.50E+06 - - - 3.2205 - 1.184 0.045 - 145.3 1 2 0 0.0031 7 0 0 0 8.87E+06 6.34E+06 - - - -0.0924 1 230117_WJC_METTL3_WT_vs_EV_F02.19266.19266.2 0.000245 22-Dec R.VVYSAFLMATPR.L sp|Q15029|U5S1_HUMAN 1 1353.7115 1.45 15245 19266 2 1353.717311 677.863 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.72 3658.9 - 1.11E+06 - - - 4.2978 - 2.539 0.498 - 535.3 1 2 0 0.0058 12 0 0 0 8.89E+06 6.12E+06 - - - 5.169 1 230117_WJC_METTL3_WT_vs_EV_F02.19267.19267.2 8.21E-05 13/24 V.ALVMLQEDELLSK.M sp|Q96A49|SYAP1_HUMAN 1 1487.7905 1.5 15246 19267 2 1487.793658 744.9025 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3659 - 1.00E+06 - - - 2.1011 - 2.672 0.516 - 592.8 1 1 0 0.0031 13 0 0 0 3.68E+07 2.45E+07 - - - 5.3736 0.973 230117_WJC_METTL3_WT_vs_EV_F02.19268.19268.2 0.64 12-Jun K.QFLDYFK[136.11].T "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 967.4895 1.44 15247 19268 2 967.493813 484.752 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.83 3659.1 - 988230 - - - 4.49 - 1.052 0.229 - 107.7 1 2 0 0.0043 7 0 0 0 9.22E+06 6.39E+06 - - - 0.8917 0.9816 230117_WJC_METTL3_WT_vs_EV_F02.19269.19269.2 0.0652 14-May K.GLLDVLPK[136.11].N "sp|O95071|UBR5_HUMAN,tr|E7ET84|E7ET84_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 861.5415 2.45 15248 19269 2 861.544868 431.778 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.84 3659.2 - 655772 - - - 3.9046 - 1.3 0.2 - 45 9 2 0 0.0034 8 0 0 0 1.71E+07 6.99E+06 - - - 0.8822 1 230117_WJC_METTL3_WT_vs_EV_F02.19270.19270.2 9.38E-06 22-Sep K.VLGTEELYGYLK.K "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1383.7286 1.07 15249 19270 2 1383.733784 692.8716 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.53 3659.4 - 577411 - - - 3.7587 - 1.959 0.526 - 170.7 1 2 0 0.0052 12 0 0 0 1.37E+07 1.28E+07 - - - 4.6937 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19271.19271.2 2.73E-05 18-Aug R.FMEPYIFGSR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 1255.5935 1.31 15250 19271 2 1255.594745 628.804 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 6 3659.5 - 568873 - - - 0.9916 - 1.79 0.503 - 252 1 2 0 0.0012 10 0 0 0 3.90E+06 2.97E+06 - - - 4.3809 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.19277.19277.2 0.0309 20-Nov R.TSLALDESLFR[166.11].G "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|H0YJH9|H0YJH9_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 5 1260.6589 1.53 15255 19277 2 1260.663207 631.3367 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.37 3660.2 - 324944 - - - 3.3871 - 2.28 0.318 - 410.7 1 2 0 0.0043 11 0 0 0 3.00E+07 1.96E+07 - - - 3.618 1 230117_WJC_METTL3_WT_vs_EV_F02.19278.19278.2 3.04E-05 20-Oct K.MALDIEIAAYR.K "sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,sp|P12036|NFH_HUMAN,sp|P07196|NFL_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 6 1264.6486 1.37 15256 19278 2 1264.653207 633.3316 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.37 3660.4 - 1.08E+06 - - - 3.6753 - 2.481 0.444 - 473.4 1 2 0 0.0046 11 0 0 0 1.17E+07 8.54E+06 - - - 4.7771 0.9898 230117_WJC_METTL3_WT_vs_EV_F02.19279.19279.2 0.232 16-Oct K.GVILLIVDK.A "sp|P78344|IF4G2_HUMAN,tr|H0YE44|H0YE44_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 8 968.627 1.88 15257 19279 2 968.631643 485.3208 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.84 3660.5 - 935460 - - - 4.7748 - 1.916 0.127 - 255.3 1 2 0 0.0046 9 0 0 0 1.30E+07 6.90E+06 - - - 1.8587 0.9867 230117_WJC_METTL3_WT_vs_EV_F02.19281.19281.2 1.39 16-Aug R.VLEALLPLK.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 994.6427 1.65 15259 19281 2 994.648938 498.3286 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3660.8 - 504113 - - - 6.3028 - 1.735 0.271 - 168.1 1 2 0 0.0063 9 0 0 0 9.77E+07 5.92E+07 - - - 2.6347 1 230117_WJC_METTL3_WT_vs_EV_F02.19282.19282.2 4.13E-06 22-Nov R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 -1 15260 19282 2 1315.791447 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3660.9 - 228278 - - - 3.8562 - 2.173 0.56 - 332.4 1 2 0 0.0051 12 0 0 0 0.00E+00 0.00E+00 - - - 5.2176 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19289.19289.2 0.00152 22-Oct R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.33 15265 19289 2 1323.803593 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3661.9 - 2.07E+06 - - - 2.2813 - 1.703 0.408 - 269 1 2 0 0.003 12 0 0 0 1.87E+09 1.41E+09 - - - 3.4544 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19290.19290.2 0.00369 16-Sep R.VLEALLPLK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1002.6569 1.65 15266 19290 2 1002.65967 502.3357 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3661.9 - 1.48E+06 - - - 2.7936 - 1.928 0.451 - 244.8 1 2 0 0.0028 9 0 0 0 9.75E+07 5.90E+07 - - - 4.2704 0.9931 230117_WJC_METTL3_WT_vs_EV_F02.19291.19291.2 0.0186 18-Jul R.VTIMGIYSIK[136.11].K "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 3 1131.6453 1.44 15267 19291 2 1131.650101 566.8299 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 8.56 3662 - 1.35E+06 - - - 4.2266 - 1.516 0.227 - 118.2 1 2 0 0.0048 10 0 0 0 2.17E+07 1.51E+07 - - - 1.8775 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19292.19292.2 0.000696 16-Oct K.IFAFDLDAK[136.11].R sp|Q96P11|NSUN5_HUMAN 1 1046.5528 0.74 15268 19292 2 1046.555418 524.2837 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 4.21 3662.1 - 961458 - - - 2.5044 - 1.947 0.455 - 220.1 1 2 0 0.0026 9 0 0 0 1.03E+07 1.39E+07 - - - 4.3284 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.19295.19295.2 0.0095 18-Oct K.VPSLVGSFIR[166.11].S "sp|P78417|GSTO1_HUMAN,tr|Q5TA02|Q5TA02_HUMAN" 2 1083.6316 0.49 15271 19295 2 1083.634315 542.8231 Glutathione S-transferase omega-1 OS=Homo sapiens OX=9606 GN=GSTO1 PE=1 SV=2 9.72 3662.4 - 206492 - - - 2.5055 - 1.689 0.217 - 183.3 1 2 0 0.0027 10 0 0 0 1.34E+06 2.76E+06 - - - 2.1059 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.19298.19298.2 0.353 24-Oct K.LGLSLVVPGGGIK[136.11].K sp|Q99747|SNAG_HUMAN 1 1216.7635 2.77 15274 19298 2 1216.766998 609.389 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3662.8 - 196753 - - - 2.9085 - 1.717 0.198 - 156.8 2 2 0 0.0035 13 0 0 0 1.13E+07 4.08E+06 - - - 1.7553 0.9882 230117_WJC_METTL3_WT_vs_EV_F02.19302.19302.2 1.27 14-May R.QWELLLEK[136.11].M "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SFF6|A0A0D9SFF6_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN,tr|A0A5F9ZHC3|A0A5F9ZHC3_HUMAN" 5 1065.595 0.82 15276 19302 2 1065.597832 533.8048 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 3663.3 - 1.30E+06 - - - 2.6605 - 1.17 0.153 - 87.6 1 2 0 0.0028 8 0 0 0 1.41E+07 1.72E+07 - - - 0.6437 0.9611 230117_WJC_METTL3_WT_vs_EV_F02.19304.19304.2 0.628 14-Jun R.QWELLLEK.M "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SFF6|A0A0D9SFF6_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN,tr|A0A5F9ZHC3|A0A5F9ZHC3_HUMAN" 5 1057.5808 0.82 15278 19304 2 1057.585994 529.7977 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 3663.5 - 1.11E+06 - - - 4.914 - 1.303 0.134 - 112.1 1 2 0 0.0052 8 0 0 0 1.41E+07 1.72E+07 - - - 0.8273 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.19305.19305.2 0.448 15/24 K.LGLSLVVPGGGIK.K sp|Q99747|SNAG_HUMAN 1 1208.7493 2.77 15279 19305 2 1208.755399 605.3819 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3663.7 - 967216 - - - 5.0796 - 2.676 0.32 - 516.8 1 2 0 0.0061 13 0 0 0 1.13E+07 4.08E+06 - - - 3.9289 0.919 230117_WJC_METTL3_WT_vs_EV_F02.19306.19306.2 0.239 14-May R.ILPWSTFR[166.11].L "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1028.5683 0.74 15280 19306 2 1028.573845 515.2914 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3663.8 - 844423 - - - 5.4182 - 0.998 0.201 - 79.4 1 2 0 0.0056 8 0 0 0 1.08E+07 1.45E+07 - - - 0.5178 0.9862 230117_WJC_METTL3_WT_vs_EV_F02.19307.19307.2 0.105 12-Jul R.LWAELLR.T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN" 3 899.5229 1.79 15281 19307 2 899.527172 450.7687 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 6 3663.9 - 550081 - - - 4.7625 - 1.485 0.175 - 189.2 1 2 0 0.0043 7 0 0 0 6.30E+06 3.52E+06 - - - 1.5851 0.89 230117_WJC_METTL3_WT_vs_EV_F02.19310.19310.2 0.196 12-Jun R.LWAELLR[166.11].T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN" 3 909.5312 1.79 15284 19310 2 909.53833 455.7729 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 6 3664.3 - 360737 - - - 7.8854 - 1.371 0.18 - 117.5 1 2 0 0.0072 7 0 0 0 6.30E+06 3.52E+06 - - - 1.368 1 230117_WJC_METTL3_WT_vs_EV_F02.19314.19314.2 3.19E-10 20-Dec R.FFDEESYSLLR.K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1404.6561 1.78 15288 19314 2 1404.660069 703.3353 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3664.8 - 151534 - - - 2.7929 - 2.472 0.633 - 389.1 1 2 0 0.0039 11 0 0 0 8.93E+07 5.02E+07 - - - 6.1634 0.988 230117_WJC_METTL3_WT_vs_EV_F02.19319.19319.2 0.0205 14/22 K.ATGILLYGLASR.L "sp|P47897|SYQ_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|F2Z2V6|F2Z2V6_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 9 1233.7081 1.66 15292 19319 2 1233.717783 617.8613 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 8.79 3665.3 - 542150 - - - 7.8309 - 2.239 0.396 - 648.7 1 2 0 0.0097 12 0 0 0 1.40E+07 8.42E+06 - - - 4.0836 1 230117_WJC_METTL3_WT_vs_EV_F02.19320.19320.2 0.00282 20-Nov R.FFDEESYSLLR[166.11].K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1414.6644 1.78 15293 19320 2 1414.66849 708.3395 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3665.5 - 314734 - - - 2.8798 - 2.342 0.54 - 293 1 2 0 0.0041 11 0 0 0 8.93E+07 5.02E+07 - - - 5.3303 1 230117_WJC_METTL3_WT_vs_EV_F02.19322.19322.3 1.24E-06 18/56 K.LLQVASPFLEPHLVR.M "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1717.9879 3.14 15295 19322 3 1717.992568 573.6699 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 6.75 3665.7 - 236836 - - - 2.702 - 3.44 0.485 - 395.7 1 2 0 0.0046 15 0 0 0 8.01E+06 2.56E+06 - - - 7.1698 0.993 230117_WJC_METTL3_WT_vs_EV_F02.19323.19323.2 0.00263 18-Aug K.YGIDEYLELK[136.11].Y "sp|P51649|SSDH_HUMAN,tr|C9J8Q5|C9J8Q5_HUMAN,tr|A0A5F9ZI23|A0A5F9ZI23_HUMAN" 3 1249.6322 0.47 15296 19323 2 1249.639068 625.8234 "Succinate-semialdehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH5A1 PE=1 SV=2" 4.14 3665.8 - 156184 - - - 5.52 - 1.667 0.314 - 153.2 1 2 0 0.0069 10 0 0 0 2.29E+06 4.89E+06 - - - 2.7845 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19332.19332.2 7.53E-05 24-Nov R.IITLTGPTNAIFK[136.11].A sp|Q15365|PCBP1_HUMAN 1 1395.8217 3.33 15304 19332 2 1395.824558 698.9181 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3666.7 - 540765 - - - 2.0461 - 2.294 0.462 - 323.5 1 2 0 0.0029 13 0 0 0 1.82E+08 5.47E+07 - - - 4.5834 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19333.19333.3 0.0197 Sep-44 R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 0.89 15305 19333 3 1315.788444 439.6027 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3666.8 - 532033 - - - 1.574 - 1.781 0.347 - 98.1 1 2 0 0.0021 12 0 0 0 2.08E+07 2.33E+07 - - - 4.008 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19334.19334.3 0.00385 Sep-44 R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1 15306 19334 3 1323.804233 442.2741 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3666.9 - 531828 - - - 2.7648 - 1.734 0.35 - 103 1 2 0 0.0037 12 0 0 0 2.05E+07 2.06E+07 - - - 3.9669 1 230117_WJC_METTL3_WT_vs_EV_F02.19337.19337.2 0.00103 18-Nov R.LGLDDFESLK[136.11].V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1143.5903 0.42 15309 19337 2 1143.594763 572.8024 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3667.1 - 363782 - - - 3.8982 - 2.109 0.49 - 244.2 1 2 0 0.0045 10 0 0 0 3.46E+07 8.20E+07 - - - 4.7417 1 230117_WJC_METTL3_WT_vs_EV_F02.19338.19338.2 2.52E-07 18-Nov K.TFTLSATLLR.H sp|Q9UEG4|ZN629_HUMAN 1 1121.6445 0.39 15310 19338 2 1121.650748 561.8295 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.41 3667.2 - 359979 - - - 5.6069 - 2.224 0.541 - 395.8 1 2 0 0.0063 10 0 0 0 5.93E+06 1.51E+07 - - - 5.266 0.998 230117_WJC_METTL3_WT_vs_EV_F02.19339.19339.2 0.003 18-Jul R.VIEQLLVGLK.D "sp|Q9BTW9|TBCD_HUMAN,tr|A0A804HJ32|A0A804HJ32_HUMAN,tr|A0A804HKT8|A0A804HKT8_HUMAN,tr|A0A804HHW7|A0A804HHW7_HUMAN,tr|A0A804HL21|A0A804HL21_HUMAN,tr|A0A804HKB9|A0A804HKB9_HUMAN,tr|A0A804HJY5|A0A804HJY5_HUMAN,tr|A0A804HI02|A0A804HI02_HUMAN,tr|A0A804HIU1|A0A804HIU1_HUMAN,tr|A0A804HJ57|A0A804HJ57_HUMAN,tr|A0A804HLF8|A0A804HLF8_HUMAN,tr|A0A804HL62|A0A804HL62_HUMAN,tr|A0A804HIC0|A0A804HIC0_HUMAN,tr|J3KR97|J3KR97_HUMAN,tr|A0A804HI57|A0A804HI57_HUMAN,tr|A0A804HIN6|A0A804HIN6_HUMAN,tr|A0A804HLI2|A0A804HLI2_HUMAN" 17 1110.7012 1.42 15311 19339 2 1110.706318 556.3579 Tubulin-specific chaperone D OS=Homo sapiens OX=9606 GN=TBCD PE=1 SV=2 5.97 3667.3 - 189832 - - - 4.5665 - 1.836 0.391 - 103.1 1 2 0 0.0051 10 0 0 0 4.82E+06 3.39E+06 - - - 3.6233 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19346.19346.2 0.000296 16-Oct K.LPFPIIDDR[166.11].N sp|P30041|PRDX6_HUMAN 1 1094.6 1.32 15316 19346 2 1094.600919 548.3073 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.21 3668.2 - 1.35E+06 - - - 0.8706 - 2.131 0.453 - 359.9 1 2 0 0.001 9 0 0 0 6.42E+07 4.85E+07 - - - 4.5754 1 230117_WJC_METTL3_WT_vs_EV_F02.19347.19347.2 8.59E-06 13/26 R.WSSLAC[160.03]NIALDAVK.M "sp|P49368|TCPG_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1546.7814 -1 15317 19347 2 1546.781043 774.398 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.83 3668.3 - 1.06E+06 - - - -0.2075 - 2.586 0.543 - 428.2 1 2 0 -0.0003 14 0 0 0 0.00E+00 0.00E+00 - - - 5.4358 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.19349.19349.3 0.000104 13/56 K.LLQVASPFLEPHLVR[166.11].M "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1727.9962 3.05 15319 19349 3 1727.996384 577.006 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 6.75 3668.6 - 946998 - - - 0.1088 - 2.344 0.434 - 159.7 1 2 0 0.0002 15 0 0 0 7.79E+06 2.56E+06 - - - 5.6014 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.19353.19353.2 0.000517 22-Dec R.NIPGITLLNVSK[136.11].L "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1275.7642 1.06 15323 19353 2 1275.768827 638.8894 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.75 3669.1 - 745205 - - - 3.637 - 2.117 0.342 - 340.7 1 2 0 0.0046 12 0 0 0 2.58E+06 2.42E+06 - - - 3.5389 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19362.19362.2 0.114 18-Sep R.LGLDDFESLK.V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1135.5761 0.42 15330 19362 2 1135.576293 568.7953 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3670.4 - 675117 - - - 0.1656 - 2.238 0.406 - 160.9 1 2 0 0.0002 10 0 0 0 3.46E+07 8.22E+07 - - - 4.2883 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19364.19364.2 0.00222 18-Sep R.FLVPIESIER[166.11].A sp|Q14249|NUCG_HUMAN 1 1211.6789 2.57 15332 19364 2 1211.682244 606.8467 "Endonuclease G, mitochondrial OS=Homo sapiens OX=9606 GN=ENDOG PE=1 SV=4" 4.53 3670.6 - 234187 - - - 2.7235 - 1.955 0.403 - 314.3 1 2 0 0.0033 10 0 0 0 1.48E+07 5.76E+06 - - - 3.8878 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.19373.19373.2 0.00224 14-Aug K.LVYVDLLR.E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 989.591 1.82 15341 19373 2 989.59575 495.8028 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.84 3671.8 - 104753 - - - 4.8333 - 1.754 0.355 - 241.5 1 2 0 0.0048 8 0 0 0 2.40E+07 1.32E+07 - - - 3.3562 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19381.19381.2 0.000444 14-Jul R.WALGQVFR.Q "sp|P26572|MGAT1_HUMAN,tr|D6RF69|D6RF69_HUMAN" 2 975.529 2.23 15347 19381 2 975.529569 488.7718 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 9.75 3672.8 - 756497 - - - 0.5464 - 1.61 0.387 - 172.1 1 2 0 0.0005 8 0 0 0 1.26E+07 5.63E+06 - - - 3.3355 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19383.19383.2 0.00213 20-Dec R.LLGLGVTDFSR[166.11].A "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 1186.6585 0.8 15349 19383 2 1186.65938 594.3365 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 5.84 3673.1 - 1.27E+06 - - - 0.7053 - 2.407 0.416 - 467.7 1 2 0 0.0008 11 0 0 0 5.80E+06 7.24E+06 - - - 4.4895 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19384.19384.2 0.000692 20-Nov R.LLGLGVTDFSR.A "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 1176.6503 0.81 15350 19384 2 1176.650184 589.3324 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 5.84 3673.2 - 858954 - - - -0.0756 - 2.359 0.413 - 345.5 1 2 0 -0.0001 11 0 0 0 5.86E+06 7.24E+06 - - - 4.4131 0.9604 230117_WJC_METTL3_WT_vs_EV_F02.19386.19386.2 6.17 14-May K.KDDFDWGK.Y "sp|Q96RT8|GCP5_HUMAN,tr|A0A0G2JPW5|A0A0G2JPW5_HUMAN,tr|A0A0G2JSA7|A0A0G2JSA7_HUMAN,tr|A0A0G2JQX1|A0A0G2JQX1_HUMAN,tr|A0A0G2JQK2|A0A0G2JQK2_HUMAN,tr|A0A087X1Z1|A0A087X1Z1_HUMAN,tr|A0A087WVZ8|A0A087WVZ8_HUMAN,tr|A0A0G2JS51|A0A0G2JS51_HUMAN,tr|A0A087WVL9|A0A087WVL9_HUMAN" 9 1009.4505 17.69 15352 19386 2 1009.451615 505.7325 Gamma-tubulin complex component 5 OS=Homo sapiens OX=9606 GN=TUBGCP5 PE=1 SV=1 4.43 3673.5 - 644724 - - - 1.0937 - 0.935 0.098 - 78.9 1 2 0 0.0011 8 0 0 0 5.22E+06 2.95E+05 - - - -0.4382 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19387.19387.2 1.52 22-Nov K.LILSLEGGYNLR[166.11].A "sp|Q9UBN7|HDAC6_HUMAN,tr|A0A2R8YCS4|A0A2R8YCS4_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 3 1356.7641 0.42 15353 19387 2 1356.764791 679.3893 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 6 3673.6 - 553443 - - - 0.5307 - 2.156 0.317 - 362.9 1 2 0 0.0007 12 0 0 0 1.34E+06 3.24E+06 - - - 3.4035 1 230117_WJC_METTL3_WT_vs_EV_F02.19388.19388.2 1.62E-05 16/24 R.TPFTTAQLLALER.K sp|P28360|MSX1_HUMAN 1 1459.8035 1.6 15354 19388 2 1459.800715 730.909 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3673.7 - 474554 - - - -1.8934 - 2.844 0.558 - 898.1 1 2 0 -0.0028 13 0 0 0 9.85E+06 6.14E+06 - - - 5.8441 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.19390.19390.2 0.0454 18-Sep R.LLLQIPSTIR[166.11].S sp|Q16394|EXT1_HUMAN 1 1162.7313 1.16 15356 19390 2 1162.731474 582.3729 Exostosin-1 OS=Homo sapiens OX=9606 GN=EXT1 PE=1 SV=2 9.75 3674 - 447756 - - - 0.1376 - 1.659 0.257 - 229.9 1 2 0 0.0002 10 0 0 0 2.33E+06 2.00E+06 - - - 2.3522 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.19393.19393.2 0.0365 18-Oct K.LFLELEPQVR[166.11].D "sp|Q13098|CSN1_HUMAN,tr|A0A096LP07|A0A096LP07_HUMAN,tr|A8K070|A8K070_HUMAN,tr|C9JFE4|C9JFE4_HUMAN,tr|A0A096LPJ3|A0A096LPJ3_HUMAN" 5 1252.7055 1.25 15359 19393 2 1252.703201 627.36 COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4 4.53 3674.4 - 369676 - - - -1.8296 - 2.067 0.275 - 377.4 1 2 0 -0.0023 10 0 0 0 5.17E+06 4.13E+06 - - - 3.0982 0.9929 230117_WJC_METTL3_WT_vs_EV_F02.19396.19396.2 0.532 14-Jul K.GVLSDLTK.V "sp|Q8NG11|TSN14_HUMAN,tr|A6NEP9|A6NEP9_HUMAN,tr|H7BXY6|H7BXY6_HUMAN" 3 831.4702 11.91 15362 19396 2 831.47 416.7424 Tetraspanin-14 OS=Homo sapiens OX=9606 GN=TSPAN14 PE=1 SV=1 5.84 3674.8 - 331980 - - - -0.2201 - 1.401 0.141 - 148.9 1 2 0 -0.0002 8 0 0 0 6.00E+06 5.04E+05 - - - 1.0993 0.9353 230117_WJC_METTL3_WT_vs_EV_F02.19400.19400.2 3.03 22-Jun K.LILSTDTLEELK.E "sp|Q9BRT2|UQCC2_HUMAN,tr|Q5TAQ0|Q5TAQ0_HUMAN,tr|V5IRT4|V5IRT4_HUMAN" 3 1373.7654 -1 15366 19400 2 1373.766567 687.89 Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1 4.14 3675.3 - 256226 - - - 0.8764 - 1.147 0.018 - 75.8 4 2 0 0.0012 12 0 0 0 0.00E+00 0.00E+00 - - - -0.7345 1 230117_WJC_METTL3_WT_vs_EV_F02.19405.19405.2 0.0025 14/24 R.ILDIDNVDLAMGK.M sp|O43615|TIM44_HUMAN 1 1415.733 2.67 15370 19405 2 1415.734446 708.8738 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3675.7 - 2.76E+06 - - - 1.0094 - 2.438 0.52 - 553.7 1 2 0 0.0014 13 0 0 0 1.80E+07 6.73E+06 - - - 5.1685 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19406.19406.2 0.000315 16-Aug K.DVDLEFLAK[136.11].M "sp|P55072|TERA_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN" 6 1056.5583 0.76 15371 19406 2 1056.560139 529.2864 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.03 3675.7 - 2.40E+06 - - - 1.7623 - 1.627 0.36 - 150.3 1 2 0 0.0019 9 0 0 0 7.38E+06 9.77E+06 - - - 3.1075 1 230117_WJC_METTL3_WT_vs_EV_F02.19407.19407.2 6.47E-05 24-Dec R.TPFTTAQLLALER[166.11].K sp|P28360|MSX1_HUMAN 1 1469.8117 1.6 15372 19407 2 1469.813761 735.9132 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3675.8 - 1.80E+06 - - - 1.3689 - 2.719 0.537 - 421.3 1 2 0 0.002 13 0 0 0 9.85E+06 6.14E+06 - - - 5.5739 1 230117_WJC_METTL3_WT_vs_EV_F02.19410.19410.2 0.00507 13/24 R.ILDIDNVDLAMGK[136.11].M sp|O43615|TIM44_HUMAN 1 1423.7472 2.67 15375 19410 2 1423.749578 712.8809 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3676.1 - 1.16E+06 - - - 1.6583 - 2.577 0.447 - 499.4 1 2 0 0.0024 13 0 0 0 1.80E+07 6.73E+06 - - - 4.7713 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19411.19411.2 0.00189 16-Aug K.IPSVLFLGK.L sp|Q8IW75|SPA12_HUMAN 1 972.6008 173.18 15376 19411 2 972.601922 487.3077 Serpin A12 OS=Homo sapiens OX=9606 GN=SERPINA12 PE=1 SV=1 8.75 3676.1 - 1.01E+06 - - - 1.1495 - 1.766 0.369 - 128.2 1 2 0 0.0011 9 0 0 0 5.28E+06 3.05E+04 - - - 3.4114 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.19412.19412.2 0.0331 16-Jun K.AYELALYLR[166.11].R "tr|G5E9Q6|G5E9Q6_HUMAN,tr|C9J0J7|C9J0J7_HUMAN" 2 1120.6156 1.42 15377 19412 2 1120.615853 561.3151 Profilin OS=Homo sapiens OX=9606 GN=PFN2 PE=1 SV=1 6.05 3676.2 - 993702 - - - 0.2115 - 1.242 0.297 - 76.1 1 2 0 0.0002 9 0 0 0 6.06E+06 4.28E+06 - - - 1.8616 0.9722 230117_WJC_METTL3_WT_vs_EV_F02.19413.19413.2 0.938 18-Jun R.LLLQIPSTIR.S sp|Q16394|EXT1_HUMAN 1 1152.723 1.16 15378 19413 2 1152.725356 577.3688 Exostosin-1 OS=Homo sapiens OX=9606 GN=EXT1 PE=1 SV=2 9.75 3676.3 - 950891 - - - 2.0057 - 1.405 0.024 - 71.7 5 2 0 0.0023 10 0 0 0 2.33E+06 2.00E+06 - - - -0.1455 0.994 230117_WJC_METTL3_WT_vs_EV_F02.19414.19414.2 9.12 12-Jun M.GLLSILR.K "sp|P36405|ARL3_HUMAN,sp|Q14517|FAT1_HUMAN,tr|A0A087WVP1|A0A087WVP1_HUMAN" 3 770.5014 1.45 15379 19414 2 770.502072 386.258 ADP-ribosylation factor-like protein 3 OS=Homo sapiens OX=9606 GN=ARL3 PE=1 SV=2 9.75 3676.4 - 931619 - - - 0.841 - 1.154 0.187 - 110.6 1 2 0 0.0006 7 0 0 0 3.33E+06 2.31E+06 - - - 0.8758 0.9864 230117_WJC_METTL3_WT_vs_EV_F02.19416.19416.2 1.43 12-Jun K.LFGELFK[136.11].L "sp|Q15032|R3HD1_HUMAN,tr|A0A804HIA8|A0A804HIA8_HUMAN,tr|H7C207|H7C207_HUMAN" 3 860.4887 1.17 15381 19416 2 860.488555 431.2516 R3H domain-containing protein 1 OS=Homo sapiens OX=9606 GN=R3HDM1 PE=1 SV=3 6 3676.6 - 713521 - - - -0.2162 - 1.382 0.092 - 74.8 2 2 0 -0.0002 7 0 0 0 3.59E+06 3.06E+06 - - - 0.6111 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19418.19418.2 3.67E-05 20-Nov K.ILEAVTLVQLK[136.11].E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1233.7788 0.86 15383 19418 2 1233.780373 617.8967 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6 3676.8 - 494218 - - - 1.2952 - 2.293 0.401 - 280.6 1 2 0 0.0016 11 0 0 0 5.17E+06 6.01E+06 - - - 4.2473 1 230117_WJC_METTL3_WT_vs_EV_F02.19419.19419.2 3.56E-07 13/22 K.YDAFLASESLIK[136.11].Q sp|P62906|RL10A_HUMAN 1 1363.7115 0.8 15384 19419 2 1363.715136 682.863 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.37 3677 - 457989 - - - 2.6787 - 2.695 0.58 - 566.1 1 2 0 0.0037 12 0 0 0 3.44E+07 4.27E+07 - - - 5.9323 0.8888 230117_WJC_METTL3_WT_vs_EV_F02.19420.19420.2 3.12 14-May K.DLPPLLLK.L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 907.5743 1.06 15385 19420 2 907.574817 454.7944 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.84 3677.1 - 289056 - - - 0.6192 - 0.984 0.036 - 62.1 5 2 0 0.0006 8 0 0 0 2.60E+06 2.44E+06 - - - -1.0542 0.9809 230117_WJC_METTL3_WT_vs_EV_F02.19423.19423.2 0.707 14-Jul K.ELEPFLLR[166.11].R sp|O14646|CHD1_HUMAN 1 1025.5785 0.65 15387 19423 2 1025.582867 513.7965 Chromodomain-helicase-DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=CHD1 PE=1 SV=2 4.53 3677.4 - 512240 - - - 4.2561 - 1.462 0.115 - 192.4 1 2 0 0.0044 8 0 0 0 2.05E+06 3.16E+06 - - - 1.0345 1 230117_WJC_METTL3_WT_vs_EV_F02.19426.19426.2 5.11E-05 14/24 R.IITLAGPTNAIFK.A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1357.7969 2.69 15390 19426 2 1357.802859 679.9057 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3677.7 - 1.56E+06 - - - 4.3615 - 2.736 0.54 - 613.3 1 2 0 0.0059 13 0 0 0 3.28E+08 1.22E+08 - - - 5.6108 0.9951 230117_WJC_METTL3_WT_vs_EV_F02.19427.19427.2 2.18 16-Jul K.LSPEELLLR[166.11].W "sp|P13797|PLST_HUMAN,sp|Q14651|PLSI_HUMAN,sp|P13796|PLSL_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|C9JAM8|C9JAM8_HUMAN" 5 1078.6262 2.41 15391 19427 2 1078.628994 540.3204 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.53 3677.9 - 1.29E+06 - - - 2.6089 - 1.503 0.144 - 135.5 1 2 0 0.0028 9 0 0 0 4.00E+07 1.66E+07 - - - 1.2825 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.19429.19429.2 0.135 18-Oct K.SLLFVNTLER.S "sp|Q9NY93|DDX56_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1190.6659 0.56 15393 19429 2 1190.670849 596.3402 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 5.72 3678.1 - 996919 - - - 4.1372 - 2.148 0.217 - 363.8 1 2 0 0.0049 10 0 0 0 8.03E+06 1.43E+07 - - - 2.7763 1 230117_WJC_METTL3_WT_vs_EV_F02.19431.19431.2 1.08E-07 16/20 K.ILEAVTLVQLK.E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1225.7646 0.86 15395 19431 2 1225.768508 613.8896 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6 3678.4 - 727620 - - - 3.2086 - 3.066 0.427 - 667.3 1 2 0 0.0039 11 0 0 0 5.17E+06 6.01E+06 - - - 5.2245 0.971 230117_WJC_METTL3_WT_vs_EV_F02.19433.19433.2 2.3 14-Jul R.LPLFGLGR[166.11].L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 881.5362 1.29 15397 19433 2 881.539807 441.7754 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3678.6 - 414318 - - - 4.0429 - 1.319 0.1 - 195.7 1 2 0 0.0036 8 0 0 0 1.11E+08 8.60E+07 - - - 0.6135 0.992 230117_WJC_METTL3_WT_vs_EV_F02.19435.19435.2 0.694 12-Jun K.LLDFLC[160.03]R.Q "sp|O75170|PP6R2_HUMAN,sp|Q8IZL8|PELP1_HUMAN,tr|E7EV54|E7EV54_HUMAN,tr|C9JFV4|C9JFV4_HUMAN,tr|I3L445|I3L445_HUMAN" 5 935.4899 0.55 15399 19435 2 935.49307 468.7522 Serine\threonine-protein phosphatase 6 regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PPP6R2 PE=1 SV=2 5.83 3678.9 - 255816 - - - 3.4175 - 1.314 0.186 - 87.8 1 2 0 0.0032 7 0 0 0 2.32E+06 4.18E+06 - - - 1.279 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.19441.19441.2 0.892 14-Sep R.LPLFGLGR.L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 871.528 1.29 15403 19441 2 871.52973 436.7713 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3679.6 - 1.83E+06 - - - 2.016 - 1.757 0.123 - 376.5 1 2 0 0.0018 8 0 0 0 1.11E+08 8.60E+07 - - - 1.6487 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.19444.19444.2 0.00385 12-Jun R.SGMFWLR[166.11].F sp|P31930|QCR1_HUMAN 1 905.4457 1.18 15406 19444 2 905.449743 453.7301 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 9.47 3679.9 - 648683 - - - 4.4497 - 1.473 0.368 - 138.6 1 2 0 0.004 7 0 0 0 3.81E+06 3.24E+06 - - - 2.985 0.9945 230117_WJC_METTL3_WT_vs_EV_F02.19445.19445.2 0.00195 18-Nov R.LTC[160.03]LGVWLDK[136.11].V sp|Q9NWT1|PK1IP_HUMAN 1 1211.6464 1.12 15407 19445 2 1211.652759 606.8305 p21-activated protein kinase-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAK1IP1 PE=1 SV=2 5.83 3680 - 525933 - - - 5.2639 - 2.115 0.234 - 372.9 1 2 0 0.0064 10 0 0 0 3.77E+06 3.37E+06 - - - 2.8582 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.19448.19448.2 0.0355 16-Aug R.VVVLGLLPR.G "sp|Q15102|PA1B3_HUMAN,tr|M0R389|M0R389_HUMAN" 2 964.6433 1.39 15410 19448 2 964.646442 483.3289 Platelet-activating factor acetylhydrolase IB subunit alpha1 OS=Homo sapiens OX=9606 GN=PAFAH1B3 PE=1 SV=1 9.72 3680.4 - 316981 - - - 3.2188 - 1.971 0.288 - 210 1 2 0 0.0031 9 0 0 0 2.42E+06 1.75E+06 - - - 3.1302 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.19451.19451.2 0.068 18-Sep R.VLALEILPER[166.11].V sp|Q56A73|SPIN4_HUMAN 1 1161.6997 0.59 15413 19451 2 1161.704593 581.8571 Spindlin-4 OS=Homo sapiens OX=9606 GN=SPIN4 PE=1 SV=1 4.53 3680.8 - 283480 - - - 4.2291 - 2.17 0.429 - 266.7 1 2 0 0.0049 10 0 0 0 2.03E+06 3.46E+06 - - - 4.3706 0.9886 230117_WJC_METTL3_WT_vs_EV_F02.19452.19452.2 6.09E-05 13/24 R.VESPVLPPVLVPR.H "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN" 2 1400.8391 2.47 15414 19452 2 1400.849905 701.4268 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 5.97 3680.9 - 398680 - - - 7.6868 - 1.838 0.468 - 438.1 1 2 0 0.0108 13 0 0 0 5.71E+06 2.31E+06 - - - 4.0565 0.9895 230117_WJC_METTL3_WT_vs_EV_F02.19454.19454.2 0.0147 22-Sep K.LILISTNGSFIR[166.11].L sp|Q6UXN9|WDR82_HUMAN 1 1342.7848 1 15416 19454 2 1342.794825 672.3997 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 9.75 3681.2 - 189194 - - - 7.4614 - 2.07 0.412 - 217.7 1 2 0 0.01 12 0 0 0 6.97E+06 6.98E+06 - - - 3.9952 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19464.19464.2 0.00285 24-Aug R.IITLAGPTNAIFK[136.11].A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1365.8111 2.69 15424 19464 2 1365.813931 683.9128 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3682.3 - 1.23E+07 - - - 2.0457 - 1.811 0.303 - 160.3 1 2 0 0.0028 13 0 0 0 3.28E+08 1.22E+08 - - - 2.8023 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19466.19466.2 0.0096 16-Nov K.WQALLVQIR[166.11].K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1135.6741 1.19 15426 19466 2 1135.678269 568.8443 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.75 3682.6 - 1.88E+06 - - - 3.641 - 2.127 0.402 - 538.9 1 2 0 0.0041 9 0 0 0 9.13E+06 7.70E+06 - - - 4.1923 0.9828 230117_WJC_METTL3_WT_vs_EV_F02.19467.19467.3 0.285 Dec-40 R.FIMILTEHLVR[166.11].C "sp|Q09161|NCBP1_HUMAN,tr|X6R941|X6R941_HUMAN" 2 1380.7827 0.85 15427 19467 3 1380.791568 461.2682 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 6.75 3682.7 - 1.84E+06 - - - 6.4239 - 2.149 0.219 - 191.6 1 2 0 0.0089 11 0 0 0 4.23E+06 4.97E+06 - - - 3.1524 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19468.19468.3 0.00757 13/40 R.FIMILTEHLVR.C "sp|Q09161|NCBP1_HUMAN,tr|X6R941|X6R941_HUMAN" 2 1370.7744 0.86 15428 19468 3 1370.779852 457.9321 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 6.75 3682.8 - 1.53E+06 - - - 3.9569 - 2.587 0.337 - 217.4 1 2 0 0.0054 11 0 0 0 4.34E+06 5.03E+06 - - - 4.9959 1 230117_WJC_METTL3_WT_vs_EV_F02.19470.19470.2 4.47E-07 18/26 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 3.44 15430 19470 2 1541.849645 771.9299 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3683.1 - 1.46E+06 - - - 2.7895 - 3.038 0.506 - 1171.6 1 2 0 0.0043 14 0 0 0 7.94E+07 2.31E+07 - - - 5.5655 1 230117_WJC_METTL3_WT_vs_EV_F02.19471.19471.2 0.00601 14/22 K.LILISTNGSFIR.L sp|Q6UXN9|WDR82_HUMAN 1 1332.7765 1 15431 19471 2 1332.78568 667.3955 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 9.75 3683.2 - 1.36E+06 - - - 6.8609 - 2.454 0.455 - 654.1 1 2 0 0.0091 12 0 0 0 6.97E+06 6.98E+06 - - - 4.7608 1 230117_WJC_METTL3_WT_vs_EV_F02.19472.19472.2 2.44E-06 14/22 K.QVVPFVYQTIVK.D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1419.8126 1.91 15432 19472 2 1419.81597 710.9136 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 3683.3 - 1.18E+06 - - - 2.382 - 2.449 0.57 - 618.7 1 2 0 0.0034 12 0 0 0 5.03E+06 2.63E+06 - - - 5.6066 0.9927 230117_WJC_METTL3_WT_vs_EV_F02.19473.19473.2 0.0286 18-Oct K.SLLFVNTLER[166.11].S "sp|Q9NY93|DDX56_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1200.6742 0.75 15433 19473 2 1200.681233 601.3444 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 5.72 3683.5 - 991262 - - - 5.8634 - 2.087 0.259 - 269.5 1 2 0 0.007 10 0 0 0 7.98E+06 1.06E+07 - - - 3.0054 0.9965 230117_WJC_METTL3_WT_vs_EV_F02.19474.19474.2 0.195 16-Aug R.MADLSELLK.E "sp|P30519|HMOX2_HUMAN,tr|I3L276|I3L276_HUMAN,tr|I3L159|I3L159_HUMAN,tr|I3L463|I3L463_HUMAN,tr|I3L4P8|I3L4P8_HUMAN,tr|A0A1B0GXH0|A0A1B0GXH0_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 8 1018.5369 0.98 15434 19474 2 1018.539389 510.2757 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 4.37 3683.6 - 896448 - - - 2.4604 - 1.507 0.172 - 134.6 1 2 0 0.0025 9 0 0 0 4.58E+06 4.66E+06 - - - 1.4971 1 230117_WJC_METTL3_WT_vs_EV_F02.19475.19475.2 1.97E-05 20-Nov K.LGGNEIVSFLK.G "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 4 1175.655 4.5 15435 19475 2 1175.660261 588.8348 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6 3683.7 - 792125 - - - 4.4545 - 2.492 0.465 - 296.2 1 2 0 0.0052 11 0 0 0 1.96E+07 4.35E+06 - - - 4.944 0.9885 230117_WJC_METTL3_WT_vs_EV_F02.19476.19476.2 0.127 16-Sep K.NLLNLDVIK.K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1040.623 1.1 15436 19476 2 1040.629375 521.3188 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3683.9 - 732346 - - - 6.13 - 1.811 0.259 - 244.8 1 2 0 0.0064 9 0 0 0 1.85E+07 1.68E+07 - - - 2.6701 1 230117_WJC_METTL3_WT_vs_EV_F02.19477.19477.2 2.67E-06 22-Dec K.QVVPFVYQTIVK[136.11].D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1427.8268 1.91 15437 19477 2 1427.83018 714.9207 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 3684 - 674039 - - - 2.3756 - 2.189 0.532 - 396.5 1 2 0 0.0034 12 0 0 0 5.03E+06 2.63E+06 - - - 5.0307 1 230117_WJC_METTL3_WT_vs_EV_F02.19478.19478.2 1.49E-05 20-Sep K.LGGNEIVSFLK[136.11].G "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 4 1183.6692 4.58 15438 19478 2 1183.674661 592.8419 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6 3684.1 - 557640 - - - 4.5933 - 2.127 0.49 - 156.1 1 2 0 0.0054 11 0 0 0 1.99E+07 4.35E+06 - - - 4.7001 1 230117_WJC_METTL3_WT_vs_EV_F02.19479.19479.2 9.28E-06 19/26 K.LLDAVDTYIPVPAR[166.11].D sp|P49411|EFTU_HUMAN 1 1551.8536 3.44 15439 19479 2 1551.858083 776.9341 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3684.3 - 498567 - - - 2.8798 - 3.081 0.587 - 1428.1 1 2 0 0.0045 14 0 0 0 7.94E+07 2.31E+07 - - - 6.1989 0.995 230117_WJC_METTL3_WT_vs_EV_F02.19481.19481.2 0.0256 18-Aug R.VLALEILPER.V sp|Q56A73|SPIN4_HUMAN 1 1151.6914 0.65 15441 19481 2 1151.696287 576.853 Spindlin-4 OS=Homo sapiens OX=9606 GN=SPIN4 PE=1 SV=1 4.53 3684.5 - 470234 - - - 4.2346 - 1.694 0.227 - 127.8 1 2 0 0.0049 10 0 0 0 2.25E+06 3.46E+06 - - - 2.1874 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19485.19485.2 2.98E-05 22-Aug K.VVLEGPAPWGFR.L "sp|Q9NR12|PDLI7_HUMAN,tr|D6RF83|D6RF83_HUMAN,tr|D6RAN1|D6RAN1_HUMAN,tr|H7BYK4|H7BYK4_HUMAN,tr|D6RH06|D6RH06_HUMAN" 5 1326.7085 4.64 15444 19485 2 1326.70971 664.3615 PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1 5.97 3684.9 - 937479 - - - 0.9444 - 1.909 0.458 - 224.9 1 2 0 0.0013 12 0 0 0 9.02E+06 1.94E+06 - - - 4.1247 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19486.19486.2 0.0232 16-Oct K.NLLNLDVIK[136.11].K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1048.6372 1.1 15445 19486 2 1048.6393 525.3259 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3684.9 - 578920 - - - 2.0064 - 1.974 0.295 - 318.1 1 2 0 0.0021 9 0 0 0 1.86E+07 1.69E+07 - - - 3.1867 0.9805 230117_WJC_METTL3_WT_vs_EV_F02.19487.19487.2 2.04 26-Aug K.VVIGMDVAASEFYR[166.11].N "sp|P13929|ENOB_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN" 2 1565.7787 2.02 15446 19487 2 1565.778914 783.8966 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.37 3684.9 - 434558 - - - 0.1143 - 1.131 0.12 - 119.5 1 2 0 0.0002 14 0 0 0 2.99E+07 1.48E+07 - - - 0.2362 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.19490.19490.2 2.68 12-Aug K.FDLIWNR.A "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|H0YEW4|H0YEW4_HUMAN,tr|A8MRA7|A8MRA7_HUMAN,tr|H0YD21|H0YD21_HUMAN" 5 962.4974 3.11 15449 19490 2 962.498656 482.256 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 5.84 3685.2 - 345877 - - - 1.3039 - 1.826 0.205 - 287.1 1 2 0 0.0013 7 0 0 0 3.57E+06 1.15E+06 - - - 2.4626 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19492.19492.2 0.00104 22-Sep K.LFGYEPTIYYPK[136.11].R "sp|Q8NCW5|NNRE_HUMAN,tr|A0A7P0Z426|A0A7P0Z426_HUMAN,tr|Q5T3I4|Q5T3I4_HUMAN,tr|A0A7P0T9Y2|A0A7P0T9Y2_HUMAN,tr|A0A7P0TAG8|A0A7P0TAG8_HUMAN,tr|Q5T3I3|Q5T3I3_HUMAN" 6 1497.7635 1.69 15451 19492 2 1497.764246 749.889 NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2 6 3685.3 - 221321 - - - 0.4854 - 2.059 0.467 - 217.4 1 2 0 0.0007 12 0 0 0 5.66E+06 3.35E+06 - - - 4.3903 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.19503.19503.3 0.00121 13/52 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 3.77 15460 19503 3 1541.847709 514.9557 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3686.6 - 1.71E+06 - - - 1.5339 - 1.978 0.414 - 165.8 1 2 0 0.0024 14 0 0 0 1.18E+07 3.11E+06 - - - 4.9677 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19504.19504.2 0.0253 14-Sep R.LWDFIENR.E "sp|Q9H000|MKRN2_HUMAN,tr|A0A7I2V5D2|A0A7I2V5D2_HUMAN,tr|A0A7I2YQI0|A0A7I2YQI0_HUMAN,tr|C9J494|C9J494_HUMAN" 4 1091.54 1.84 15461 19504 2 1091.541029 546.7773 Probable E3 ubiquitin-protein ligase makorin-2 OS=Homo sapiens OX=9606 GN=MKRN2 PE=1 SV=2 4.37 3686.6 - 1.24E+06 - - - 0.9482 - 2.03 0.377 - 301.6 1 2 0 0.001 8 0 0 0 8.30E+06 4.51E+06 - - - 3.9606 1 230117_WJC_METTL3_WT_vs_EV_F02.19506.19506.2 0.000193 22-Nov K.LFGYEPTIYYPK.R "sp|Q8NCW5|NNRE_HUMAN,tr|A0A7P0Z426|A0A7P0Z426_HUMAN,tr|Q5T3I4|Q5T3I4_HUMAN,tr|A0A7P0T9Y2|A0A7P0T9Y2_HUMAN,tr|A0A7P0TAG8|A0A7P0TAG8_HUMAN,tr|Q5T3I3|Q5T3I3_HUMAN" 6 1489.7493 1.69 15463 19506 2 1489.752187 745.8819 NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2 6 3686.9 - 968647 - - - 1.9252 - 2.272 0.476 - 370.4 1 2 0 0.0029 12 0 0 0 5.66E+06 3.35E+06 - - - 4.7151 1 230117_WJC_METTL3_WT_vs_EV_F02.19514.19514.2 0.000101 22-Nov R.LLTWVIGTGSPR[166.11].L sp|Q92616|GCN1_HUMAN 1 1308.7429 1.63 15471 19514 2 1308.751779 655.3787 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.75 3687.8 - 455382 - - - 6.7523 - 2.347 0.512 - 535.8 1 2 0 0.0088 12 0 0 0 4.39E+06 2.69E+06 - - - 5.0646 1 230117_WJC_METTL3_WT_vs_EV_F02.19515.19515.2 1.33E-06 13/28 R.VGPDVVTDPAFLVTR[166.11].S sp|Q9NV31|IMP3_HUMAN 1 1594.8594 1.62 15472 19515 2 1594.864182 798.437 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3687.9 - 424988 - - - 2.9808 - 2.215 0.547 - 382.3 1 2 0 0.0048 15 0 0 0 5.00E+06 3.09E+06 - - - 5.0348 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.19516.19516.2 0.119 14-Jul R.LWLLDDSK.T "sp|O43639|NCK2_HUMAN,sp|P16333|NCK1_HUMAN,tr|E7EPF5|E7EPF5_HUMAN,tr|E7ERP6|E7ERP6_HUMAN,tr|C9J0K5|C9J0K5_HUMAN,tr|C9K098|C9K098_HUMAN,tr|C9J869|C9J869_HUMAN,tr|C9JVV5|C9JVV5_HUMAN,tr|E9PEE2|E9PEE2_HUMAN,tr|H7C5C7|H7C5C7_HUMAN" 10 988.5229 1.24 15473 19516 2 988.524265 495.2687 Cytoplasmic protein NCK2 OS=Homo sapiens OX=9606 GN=NCK2 PE=1 SV=2 4.21 3688 - 397593 - - - 1.3333 - 1.585 0.166 - 129 1 2 0 0.0013 8 0 0 0 2.17E+06 1.76E+06 - - - 1.6558 1 230117_WJC_METTL3_WT_vs_EV_F02.19524.19524.2 1.00E-05 20-Dec K.VGEVTYVELFK[136.11].D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1290.6951 1.84 15480 19524 2 1290.697456 646.3548 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.53 3689 - 2.04E+06 - - - 1.8215 - 2.604 0.54 - 650.8 1 2 0 0.0024 11 0 0 0 5.56E+07 3.02E+07 - - - 5.6177 1 230117_WJC_METTL3_WT_vs_EV_F02.19525.19525.2 1.97E-05 20-Dec R.LLESLDQLELR.V sp|O95816|BAG2_HUMAN 1 1327.7347 9.92 15481 19525 2 1327.738567 664.8746 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.14 3689 - 1.53E+07 - - - 2.8891 - 2.538 0.481 - 520 1 2 0 0.0038 11 0 0 0 1.71E+08 1.73E+07 - - - 5.1121 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.19527.19527.2 0.0683 16-Aug R.EILSPLFPR.N "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1070.6124 -1 15483 19527 2 1070.613932 536.3135 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6.1 3689.2 - 1.27E+06 - - - 1.402 - 1.463 0.251 - 175.1 1 2 0 0.0015 9 0 0 0 0.00E+00 0.00E+00 - - - 1.9952 1 230117_WJC_METTL3_WT_vs_EV_F02.19528.19528.2 2.07E-05 16/28 R.VGPDVVTDPAFLVTR.S sp|Q9NV31|IMP3_HUMAN 1 1584.8512 1.62 15484 19528 2 1584.855556 793.4329 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3689.3 - 1.08E+06 - - - 2.775 - 2.595 0.5 - 639.4 1 2 0 0.0044 15 0 0 0 5.00E+06 3.09E+06 - - - 5.0771 0.9922 230117_WJC_METTL3_WT_vs_EV_F02.19530.19530.2 1.43 12-Jul R.YVLSFLR.T "sp|Q96SI1|KCD15_HUMAN,tr|V9GYY8|V9GYY8_HUMAN,tr|K7EN63|K7EN63_HUMAN" 3 896.512 2.78 15486 19530 2 896.514985 449.2633 BTB\POZ domain-containing protein KCTD15 OS=Homo sapiens OX=9606 GN=KCTD15 PE=1 SV=1 8.75 3689.6 - 912937 - - - 3.3418 - 1.437 0.146 - 181.6 1 2 0 0.003 7 0 0 0 1.95E+06 7.02E+05 - - - 1.2672 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.19533.19533.2 0.0056 16-Aug R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 -1 15489 19533 2 1006.571767 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3690 - 613294 - - - 1.8568 - 1.616 0.341 - 134.2 1 2 0 0.0019 9 0 0 0 0.00E+00 0.00E+00 - - - 2.9476 1 230117_WJC_METTL3_WT_vs_EV_F02.19534.19534.2 8.20E-06 22-Oct R.ELYLEDSPLELK.L sp|Q8TEM1|PO210_HUMAN 1 1447.7446 1.86 15490 19534 2 1447.747181 724.8796 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4 3690.1 - 611113 - - - 1.7641 - 2.261 0.473 - 285.2 1 2 0 0.0026 12 0 0 0 2.01E+06 1.08E+06 - - - 4.6803 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19535.19535.2 0.0199 14/24 R.LSAYVSYGGLLMR.L "sp|P52434|RPAB3_HUMAN,tr|C9JLU1|C9JLU1_HUMAN" 2 1428.7435 1.06 15491 19535 2 1428.74415 715.379 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4" 8.59 3690.2 - 609686 - - - 0.4395 - 2.591 0.402 - 608.6 1 2 0 0.0006 13 0 0 0 2.36E+06 2.24E+06 - - - 4.4534 1 230117_WJC_METTL3_WT_vs_EV_F02.19536.19536.2 1.32E-05 20-Dec K.IDAELVLPTIR[166.11].S "sp|O95985|TOP3B_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 2 1248.7317 1.13 15492 19536 2 1248.736903 625.3731 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 4.37 3690.4 - 606665 - - - 4.1602 - 2.602 0.562 - 806.6 1 2 0 0.0052 11 0 0 0 2.32E+06 2.05E+06 - - - 5.7773 1 230117_WJC_METTL3_WT_vs_EV_F02.19537.19537.2 1.91E-06 20-Dec K.IDAELVLPTIR.S "sp|O95985|TOP3B_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 2 1238.7234 0.88 15493 19537 2 1238.729489 620.369 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 4.37 3690.5 - 542401 - - - 4.8849 - 2.688 0.455 - 395 1 2 0 0.0061 11 0 0 0 1.69E+06 1.91E+06 - - - 5.0747 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19539.19539.2 6.88E-06 24-Oct K.LVDSMGWELASVR[166.11].R "sp|O94761|RECQ4_HUMAN,tr|A0A087WTJ0|A0A087WTJ0_HUMAN,tr|A0A087X072|A0A087X072_HUMAN" 3 1471.7369 0.9 15495 19539 2 1471.737951 736.8757 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.37 3690.7 - 499100 - - - 0.7345 - 1.815 0.49 - 218.4 1 2 0 0.0011 13 0 0 0 1.01E+06 1.12E+06 - - - 4.1897 1 230117_WJC_METTL3_WT_vs_EV_F02.19547.19547.2 0.000313 18-Oct R.AEVVSLLLDR.K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1113.6394 1.26 15502 19547 2 1113.643391 557.827 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3691.6 - 2.34E+06 - - - 3.6071 - 2.289 0.484 - 411.4 1 2 0 0.004 10 0 0 0 5.01E+07 3.97E+07 - - - 4.9261 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19551.19551.2 0.000919 14-Jul K.YWYLGPLK.L "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A0G2JLD0|A0A0G2JLD0_HUMAN,tr|E9PG39|E9PG39_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A0G2JLG5|A0A0G2JLG5_HUMAN,tr|A0A3B3ISZ0|A0A3B3ISZ0_HUMAN" 8 1038.5539 2.21 15506 19551 2 1038.555652 520.2842 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 8.5 3691.9 - 1.02E+06 - - - 1.7313 - 1.521 0.358 - 212.7 1 2 0 0.0018 8 0 0 0 7.48E+06 3.38E+06 - - - 2.9494 1 230117_WJC_METTL3_WT_vs_EV_F02.19554.19554.2 0.021 13/20 R.VLITTLITAGR[166.11].L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1166.7262 0.94 15509 19554 2 1166.728194 584.3704 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3692.3 - 662685 - - - 1.6842 - 2.571 0.455 - 541.7 1 2 0 0.002 11 0 0 0 1.42E+07 1.51E+07 - - - 4.9556 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.19557.19557.2 0.0033 18-Nov R.LIESLFTIQK[136.11].M "sp|Q12789|TF3C1_HUMAN,tr|H3BU37|H3BU37_HUMAN" 2 1198.7053 0.91 15512 19557 2 1198.710032 600.3599 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 6 3692.7 - 582839 - - - 3.9684 - 1.886 0.382 - 271.5 1 2 0 0.0048 10 0 0 0 3.99E+06 4.37E+06 - - - 3.6319 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.19560.19560.2 0.0135 12-May R.EFEFLMR.Q sp|P85037|FOXK1_HUMAN 1 970.4582 4.18 15515 19560 2 970.460401 486.2364 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 4.53 3693.1 - 534422 - - - 2.2278 - 1.206 0.277 - 96.9 1 2 0 0.0022 7 0 0 0 2.27E+06 5.42E+05 - - - 1.6797 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19562.19562.2 0.0303 20-Dec R.VLITTLITAGR.L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1156.718 0.94 15517 19562 2 1156.720482 579.3663 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3693.4 - 456071 - - - 2.1812 - 2.205 0.39 - 464.4 1 2 0 0.0025 11 0 0 0 1.42E+07 1.51E+07 - - - 4.0599 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19565.19565.2 0.00307 18-Oct K.IELFADVVPK.T "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 1129.6383 1.69 15519 19565 2 1129.641116 565.8264 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.37 3693.7 - 4.20E+06 - - - 2.4831 - 2.108 0.414 - 281.3 1 2 0 0.0028 10 0 0 0 6.87E+07 4.06E+07 - - - 4.1795 1 230117_WJC_METTL3_WT_vs_EV_F02.19566.19566.2 5.17E-05 15/26 R.LIVVLEGASLETVK.V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1469.8705 1.12 15520 19566 2 1469.872502 735.9425 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3693.8 - 387835 - - - 1.3647 - 3.005 0.54 - 720.6 1 2 0 0.002 14 0 0 0 3.16E+06 2.82E+06 - - - 5.7899 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19570.19570.2 0.00193 22-Dec R.LLEITEGSEFLR.L "sp|Q86U28|ISCA2_HUMAN,tr|J3QSS7|J3QSS7_HUMAN" 2 1405.7453 2.43 15524 19570 2 1405.749424 703.8799 "Iron-sulfur cluster assembly 2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=ISCA2 PE=1 SV=2" 4.25 3694.3 - 418272 - - - 2.9365 - 2.291 0.454 - 485.6 1 2 0 0.0041 12 0 0 0 3.23E+06 1.33E+06 - - - 4.5742 0.999 230117_WJC_METTL3_WT_vs_EV_F02.19571.19571.2 0.000789 20-Oct K.TMVMEALSLAK[136.11].S "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1200.6338 0.001 15525 19571 2 1200.634413 601.3242 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 5.66 3694.4 - 334707 - - - 0.538 - 1.612 0.305 - 190.1 1 2 0 0.0006 11 0 0 0 0.00E+00 4.37E+06 - - - 2.5852 1 230117_WJC_METTL3_WT_vs_EV_F02.19572.19572.2 0.00976 13/26 R.LIVVLEGASLETVK[136.11].V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1477.8847 1.12 15526 19572 2 1477.890357 739.9496 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3694.5 - 322248 - - - 3.8305 - 2.767 0.419 - 475.8 1 2 0 0.0057 14 0 0 0 3.16E+06 2.82E+06 - - - 4.688 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.19575.19575.2 0.000136 24-Nov R.LSAYVSYGGLLMR[166.11].L "sp|P52434|RPAB3_HUMAN,tr|C9JLU1|C9JLU1_HUMAN" 2 1438.7518 1.01 15529 19575 2 1438.751386 720.3832 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4" 8.59 3694.9 - 265140 - - - -0.2822 - 1.889 0.34 - 342.5 1 2 0 -0.0004 13 0 0 0 2.41E+06 2.38E+06 - - - 3.1845 0.9864 230117_WJC_METTL3_WT_vs_EV_F02.19576.19576.2 1.83 12-Jun R.AFLPLLK.A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 800.516 1.31 15530 19576 2 800.516441 401.2653 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3695 - 244669 - - - 0.5372 - 1.224 0.092 - 181.3 1 2 0 0.0004 7 0 0 0 1.57E+07 1.20E+07 - - - 0.3608 0.999 230117_WJC_METTL3_WT_vs_EV_F02.19579.19579.2 1.22E-05 22-Nov R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 -1 15533 19579 2 1315.790928 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3695.4 - 132841 - - - 3.4618 - 2.124 0.351 - 335.5 1 2 0 0.0046 12 0 0 0 0.00E+00 0.00E+00 - - - 3.6141 0.997 230117_WJC_METTL3_WT_vs_EV_F02.19586.19586.2 0.00727 18-Oct R.EALLAALGYK[136.11].N sp|Q9BU76|MMTA2_HUMAN 1 1055.6106 0.78 15538 19586 2 1055.616357 528.8126 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3696.1 - 1.22E+06 - - - 5.4092 - 2.364 0.339 - 316.6 1 2 0 0.0057 10 0 0 0 2.50E+07 3.18E+07 - - - 3.9446 0.9963 230117_WJC_METTL3_WT_vs_EV_F02.19587.19587.2 0.00806 18-Sep R.EALLAALGYK.N sp|Q9BU76|MMTA2_HUMAN 1 1047.5964 0.63 15539 19587 2 1047.602452 524.8055 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3696.3 - 939206 - - - 5.7322 - 2.204 0.371 - 219.4 1 2 0 0.006 10 0 0 0 2.50E+07 3.97E+07 - - - 3.9852 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.19588.19588.2 0.000767 20-Oct K.VAPGFQFFATR.R sp|Q9NU22|MDN1_HUMAN 1 1239.64 0.85 15540 19588 2 1239.645762 620.8273 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 9.72 3696.4 - 696516 - - - 4.6134 - 1.955 0.409 - 304.9 1 2 0 0.0057 11 0 0 0 4.08E+06 4.79E+06 - - - 3.8736 0.9622 230117_WJC_METTL3_WT_vs_EV_F02.19592.19592.2 0.00012 22-Aug K.VIHDNFGIVEGL.M "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1311.6823 - 15544 19592 2 1311.686009 656.8484 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.35 3696.9 - 373024 - - - 2.8261 - 2.173 0.412 - 218 1 1 0 0.0037 12 0 0 0 - - - - - 4.1249 1 230117_WJC_METTL3_WT_vs_EV_F02.19594.19594.2 6.22E-07 22-Dec K.FATEDEAWAFVR.K sp|O60930|RNH1_HUMAN 1 1440.6674 1.1 15546 19594 2 1440.673488 721.341 Ribonuclease H1 OS=Homo sapiens OX=9606 GN=RNASEH1 PE=1 SV=2 4.14 3697.2 - 369366 - - - 4.2397 - 2.627 0.534 - 469.1 1 2 0 0.0061 12 0 0 0 2.53E+06 2.30E+06 - - - 5.5245 0.9725 230117_WJC_METTL3_WT_vs_EV_F02.19596.19596.2 0.406 14-May K.VLIVVPFR.E "sp|Q68CQ4|UTP25_HUMAN,tr|H7C2R4|H7C2R4_HUMAN" 2 941.6062 1.43 15548 19596 2 941.610892 471.8104 U3 small nucleolar RNA-associated protein 25 homolog OS=Homo sapiens OX=9606 GN=UTP25 PE=1 SV=2 9.72 3697.4 - 342577 - - - 4.9585 - 1.278 0.224 - 52.2 5 2 0 0.0047 8 0 0 0 3.21E+06 2.25E+06 - - - 1.1216 0.9886 230117_WJC_METTL3_WT_vs_EV_F02.19604.19604.2 0.00335 16-Jun K.TFDPYIIIR[166.11].A sp|Q13601|KRR1_HUMAN 1 1146.6313 0.001 15555 19604 2 1146.637834 574.3229 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 5.5 3698.4 - 1.85E+06 - - - 5.7281 - 1.356 0.333 - 104.6 1 2 0 0.0066 9 0 0 0 0.00E+00 1.89E+07 - - - 2.3795 0.9955 230117_WJC_METTL3_WT_vs_EV_F02.19605.19605.2 0.000394 20-Oct K.VAPGFQFFATR[166.11].R sp|Q9NU22|MDN1_HUMAN 1 1249.6483 0.85 15556 19605 2 1249.655273 625.8314 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 9.72 3698.6 - 656967 - - - 5.5696 - 1.919 0.353 - 311.6 1 2 0 0.007 11 0 0 0 4.08E+06 4.79E+06 - - - 3.4094 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19608.19608.2 0.0143 14-Aug R.YELALILK.A sp|P82932|RT06_HUMAN 1 961.5848 2.45 15559 19608 2 961.587201 481.7997 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3698.7 - 1.87E+06 - - - 2.4772 - 1.588 0.417 - 194.7 1 2 0 0.0024 8 0 0 0 1.23E+07 5.00E+06 - - - 3.515 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.19613.19613.2 0.0166 20-Nov R.LALVISELEGK[136.11].A "sp|Q12899|TRI26_HUMAN,tr|A2AE48|A2AE48_HUMAN" 2 1178.7002 1.07 15564 19613 2 1178.704018 590.3574 Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1 4.53 3699.2 - 951525 - - - 3.2476 - 2.375 0.332 - 312 1 2 0 0.0038 11 0 0 0 4.80E+06 4.50E+06 - - - 3.832 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19614.19614.2 0.0634 14-Aug R.YELALILK[136.11].A sp|P82932|RT06_HUMAN 1 969.599 2.47 15565 19614 2 969.60133 485.8068 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3699.2 - 745664 - - - 2.3835 - 1.592 0.404 - 186.8 1 2 0 0.0023 8 0 0 0 1.24E+07 5.00E+06 - - - 3.4266 0.9768 230117_WJC_METTL3_WT_vs_EV_F02.19628.19628.2 0.39 12-Jul R.AFLPLLK[136.11].A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 808.5302 1.32 15577 19628 2 808.533142 405.2724 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3700.9 - 3.18E+06 - - - 3.6251 - 1.372 0.072 - 239.5 1 2 0 0.0029 7 0 0 0 1.58E+07 1.20E+07 - - - 0.574 0.9937 230117_WJC_METTL3_WT_vs_EV_F02.19631.19631.2 0.726 14-Aug R.LSFFGLEK.L "sp|Q9ULF5|S39AA_HUMAN,tr|E7EV45|E7EV45_HUMAN,tr|E7ENT5|E7ENT5_HUMAN" 3 939.5066 0.47 15580 19631 2 939.507337 470.7606 Zinc transporter ZIP10 OS=Homo sapiens OX=9606 GN=SLC39A10 PE=1 SV=2 6 3701.3 - 970739 - - - 0.8175 - 1.252 0.153 - 143.2 1 2 0 0.0008 8 0 0 0 2.57E+06 5.46E+06 - - - 0.8486 0.9734 230117_WJC_METTL3_WT_vs_EV_F02.19636.19636.2 0.995 14-Jun K.VAIIIPFR.N "sp|P15291|B4GT1_HUMAN,sp|O43286|B4GT5_HUMAN,tr|Q86XA6|Q86XA6_HUMAN" 3 927.5906 0.66 15585 19636 2 927.595682 464.8026 "Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5" 9.72 3702 - 328856 - - - 5.5078 - 1.667 0.117 - 112.4 1 2 0 0.0051 8 0 0 0 5.69E+06 8.67E+06 - - - 1.4448 0.9738 230117_WJC_METTL3_WT_vs_EV_F02.19642.19642.2 0.000497 18-Dec R.IINDLLQSLR.S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1183.6925 2.12 15589 19642 2 1183.701346 592.8535 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3702.8 - 2.04E+06 - - - 7.4969 - 2.317 0.171 - 471.1 1 2 0 0.0089 10 0 0 0 9.79E+07 4.62E+07 - - - 2.6467 0.9814 230117_WJC_METTL3_WT_vs_EV_F02.19643.19643.2 0.646 18-Sep R.IINDLLQSLR[166.11].S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1193.7007 2.12 15590 19643 2 1193.708789 597.8576 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3702.8 - 926215 - - - 6.7412 - 2.072 0.202 - 204.5 1 2 0 0.008 10 0 0 0 9.79E+07 4.62E+07 - - - 2.564 1 230117_WJC_METTL3_WT_vs_EV_F02.19644.19644.2 0.000168 18-Nov R.LGLEDFESLK[136.11].V sp|Q15208|STK38_HUMAN 1 1157.606 0.57 15591 19644 2 1157.609018 579.8103 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3702.9 - 1.17E+06 - - - 2.646 - 2.551 0.478 - 312.6 1 2 0 0.0031 10 0 0 0 1.88E+08 3.27E+08 - - - 5.1846 1 230117_WJC_METTL3_WT_vs_EV_F02.19649.19649.2 0.00649 18-Nov R.LGLEDFESLK.V sp|Q15208|STK38_HUMAN 1 1149.5918 0.57 15596 19649 2 1149.59405 575.8032 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3703.2 - 586822 - - - 1.9964 - 2.287 0.46 - 286.7 1 2 0 0.0023 10 0 0 0 1.88E+08 3.27E+08 - - - 4.7469 1 230117_WJC_METTL3_WT_vs_EV_F02.19655.19655.2 0.00676 22-Dec Y.AIYELAVASFPK.K "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6R9C3|D6R9C3_HUMAN" 4 1307.7125 2.28 15602 19655 2 1307.716072 654.8635 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 6.05 3703.9 - 164116 - - - 2.7017 - 2.647 0.465 - 525.7 1 1 0 0.0035 12 0 0 0 3.59E+06 1.57E+06 - - - 5.0356 0.8951 230117_WJC_METTL3_WT_vs_EV_F02.19656.19656.2 1.63 18-Jun K.ILFDGIPLEK.M sp|P22033|MUTA_HUMAN 1 1143.654 1.66 15603 19656 2 1143.659726 572.8343 "Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4" 4.37 3704 - 150119 - - - 5.04 - 1.164 0.093 - 66.4 1 2 0 0.0058 10 0 0 0 1.58E+07 9.54E+06 - - - 0.15 1 230117_WJC_METTL3_WT_vs_EV_F02.19659.19659.2 1.11E-07 14/26 K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 2.59 15606 19659 2 1772.81246 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3704.4 - 118633 - - - 5.1275 - 2.673 0.659 - 783 1 2 0 0.0091 14 0 0 0 4.70E+06 1.81E+06 - - - 6.3728 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19665.19665.2 0.00222 16-Sep K.ALEVYDLIR.T "sp|Q9H5X1|CIA2A_HUMAN,tr|H0YKV4|H0YKV4_HUMAN" 2 1090.6023 1.65 15611 19665 2 1090.603842 546.3084 Cytosolic iron-sulfur assembly component 2A OS=Homo sapiens OX=9606 GN=CIAO2A PE=1 SV=1 4.37 3705 - 3.15E+06 - - - 1.4506 - 2.038 0.399 - 379.1 1 2 0 0.0016 9 0 0 0 9.30E+06 5.63E+06 - - - 4.0473 0.999 230117_WJC_METTL3_WT_vs_EV_F02.19671.19671.2 0.035 14-Aug K.VAIIIPFR[166.11].N "sp|P15291|B4GT1_HUMAN,sp|O43286|B4GT5_HUMAN,tr|Q86XA6|Q86XA6_HUMAN" 3 937.5988 0.84 15617 19671 2 937.599579 469.8067 "Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5" 9.72 3705.4 - 1.54E+06 - - - 0.785 - 1.838 0.22 - 254.6 1 2 0 0.0007 8 0 0 0 5.48E+06 6.48E+06 - - - 2.5014 0.999 230117_WJC_METTL3_WT_vs_EV_F02.19673.19673.2 0.157 18-Aug R.IEGLLAAFPK[136.11].L "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|E9PK34|E9PK34_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 4 1065.6314 2.38 15619 19673 2 1065.633979 533.823 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6 3705.5 - 1.29E+06 - - - 2.4371 - 1.866 0.264 - 125.2 1 2 0 0.0026 10 0 0 0 2.56E+07 1.07E+07 - - - 2.7313 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19675.19675.2 0.000473 18-Aug R.TALYNYIFAK.K "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1202.6336 2.94 15621 19675 2 1202.633974 602.3241 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 8.17 3705.7 - 817981 - - - 0.3442 - 1.608 0.451 - 172.2 1 2 0 0.0004 10 0 0 0 5.23E+06 1.78E+06 - - - 3.6978 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.19676.19676.2 0.00108 20-Dec K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 6.77 15622 19676 2 1276.706894 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3705.8 - 735950 - - - 3.2827 - 2.644 0.304 - 727.4 1 2 0 0.0042 11 0 0 0 4.93E+06 7.29E+05 - - - 3.9153 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19677.19677.2 0.000459 22-Oct R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.01 15623 19677 2 1323.803413 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3705.9 - 623871 - - - 2.1453 - 2.057 0.389 - 258.3 1 2 0 0.0028 12 0 0 0 2.64E+06 2.62E+06 - - - 3.811 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.19678.19678.2 0.0211 12-May R.EAYFWLR[166.11].Q sp|Q8TCJ2|STT3B_HUMAN 1 993.4948 1.03 15624 19678 2 993.49537 497.7547 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1 6.1 3706 - 534479 - - - 0.6019 - 1.298 0.336 - 115.6 1 2 0 0.0006 7 0 0 0 4.55E+06 4.43E+06 - - - 2.3489 1 230117_WJC_METTL3_WT_vs_EV_F02.19679.19679.2 1.60E-07 26-Nov K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 2.59 15625 19679 2 1762.800064 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3706.1 - 491772 - - - 2.816 - 2.353 0.632 - 369.5 1 2 0 0.005 14 0 0 0 4.70E+06 1.81E+06 - - - 5.8547 0.9927 230117_WJC_METTL3_WT_vs_EV_F02.19681.19681.2 0.0112 20-Aug R.TFAVTDELVFK.D sp|O60826|CCD22_HUMAN 1 1268.6653 999 15627 19681 2 1268.661659 635.3399 Coiled-coil domain-containing protein 22 OS=Homo sapiens OX=9606 GN=CCDC22 PE=1 SV=1 4.37 3706.4 - 312778 - - - -2.8345 - 1.592 0.307 - 176.7 1 2 0 -0.0036 11 0 0 0 9.32E+05 0.00E+00 - - - 2.5653 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.19682.19682.2 1.95E-05 13/24 R.LENLGIPEEELLR.Q sp|Q01658|NC2B_HUMAN 1 1523.8195 2.98 15628 19682 2 1523.817978 762.917 Protein Dr1 OS=Homo sapiens OX=9606 GN=DR1 PE=1 SV=1 4.09 3706.5 - 307609 - - - -1.0139 - 2.85 0.37 - 412 1 2 0 -0.0015 13 0 0 0 2.16E+06 7.26E+05 - - - 4.4613 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.19686.19686.2 0.00835 12-Jul R.EAYFWLR.Q sp|Q8TCJ2|STT3B_HUMAN 1 983.4865 1.02 15631 19686 2 983.48812 492.7505 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1 6.1 3706.9 - 471543 - - - 1.6452 - 1.29 0.328 - 209.1 1 2 0 0.0016 7 0 0 0 4.61E+06 4.54E+06 - - - 2.2699 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19687.19687.2 6.45E-05 18-Aug K.LFGYEMAEFK[136.11].V sp|Q9UKD2|MRT4_HUMAN 1 1241.5882 0.63 15632 19687 2 1241.589973 621.8014 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 4.53 3707 - 354401 - - - 1.4304 - 1.502 0.477 - 143 1 2 0 0.0018 10 0 0 0 3.53E+06 5.59E+06 - - - 3.6991 0.9723 230117_WJC_METTL3_WT_vs_EV_F02.19691.19691.2 8.98 12-Jun R.FIPPWLK.K "sp|O43491|E41L2_HUMAN,tr|E9PIG0|E9PIG0_HUMAN,tr|A0A2R8Y5B3|A0A2R8Y5B3_HUMAN,tr|E9PII3|E9PII3_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|E9PK52|E9PK52_HUMAN,tr|E9PRG1|E9PRG1_HUMAN,tr|E9PJP4|E9PJP4_HUMAN,tr|E9PQD2|E9PQD2_HUMAN,tr|E9PQN0|E9PQN0_HUMAN" 10 899.5269 2.06 15636 19691 2 899.5287 450.7707 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 8.75 3707.4 - 219841 - - - 1.9899 - 1.053 0.088 - 92.7 1 2 0 0.0018 7 0 0 0 5.19E+07 2.51E+07 - - - -0.146 0.9948 230117_WJC_METTL3_WT_vs_EV_F02.19693.19693.2 0.00684 14-Aug R.GLDIYVWR[166.11].G sp|Q13045|FLII_HUMAN 1 1030.5475 1.09 15638 19693 2 1030.55357 516.281 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3707.6 - 134332 - - - 5.8551 - 1.763 0.371 - 219.2 1 2 0 0.006 8 0 0 0 4.76E+06 4.36E+06 - - - 3.4894 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19697.19697.2 0.072 14-Jul R.LLFFAPTR.R sp|Q07820|MCL1_HUMAN 1 963.5542 4.74 15641 19697 2 963.555629 482.7844 Induced myeloid leukemia cell differentiation protein Mcl-1 OS=Homo sapiens OX=9606 GN=MCL1 PE=1 SV=3 9.75 3708.1 - 1.11E+06 - - - 1.4955 - 1.557 0.354 - 183.5 1 2 0 0.0014 8 0 0 0 8.13E+06 1.71E+06 - - - 2.9905 0.9954 230117_WJC_METTL3_WT_vs_EV_F02.19707.19707.2 1.37 12-Aug K.LTFLDLR.N "sp|Q9H9A6|LRC40_HUMAN,tr|X6R5P2|X6R5P2_HUMAN" 2 876.5069 1.31 15648 19707 2 876.507161 439.2607 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.84 3709.1 - 941037 - - - 0.2944 - 1.594 0.096 - 261.3 1 2 0 0.0003 7 0 0 0 6.46E+06 4.92E+06 - - - 1.2273 0.975 230117_WJC_METTL3_WT_vs_EV_F02.19708.19708.2 0.00725 16-Sep K.GLFEVNPWK[136.11].R "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1096.5797 1.55 15649 19708 2 1096.584728 549.2971 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 6 3709.2 - 1.43E+06 - - - 4.6025 - 1.63 0.075 - 199.8 1 2 0 0.005 9 0 0 0 1.45E+07 9.35E+06 - - - 1.0069 0.9243 230117_WJC_METTL3_WT_vs_EV_F02.19709.19709.2 0.149 20-Sep K.LIGNHPDVLPF.A "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 1220.6554 - 15650 19709 2 1220.657552 611.335 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 5.08 3709.3 - 1.42E+06 - - - 1.7966 - 1.581 0.288 - 185 1 1 0 0.0022 11 0 0 0 - - - - - 2.4066 1 230117_WJC_METTL3_WT_vs_EV_F02.19710.19710.2 2.09E-08 17/22 R.LPADTC[160.03]LLEFAR.L "sp|Q8NF37|PCAT1_HUMAN,tr|A0A0G2JQ62|A0A0G2JQ62_HUMAN,tr|A0A0G2JRI7|A0A0G2JRI7_HUMAN" 3 1404.7071 1.42 15651 19710 2 1404.709394 703.3608 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 4.37 3709.5 - 963132 - - - 1.6075 - 2.834 0.633 - 1381.3 1 2 0 0.0023 12 0 0 0 5.25E+06 3.71E+06 - - - 6.4565 1 230117_WJC_METTL3_WT_vs_EV_F02.19713.19713.2 0.00291 14/20 R.VAQFLVIYAPR.R sp|Q9H2M9|RBGPR_HUMAN 1 1275.7339 1.54 15654 19713 2 1275.73689 638.8742 Rab3 GTPase-activating protein non-catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP2 PE=1 SV=1 8.72 3709.9 - 784479 - - - 2.31 - 2.895 0.441 - 1042.4 1 2 0 0.0029 11 0 0 0 3.86E+06 2.51E+06 - - - 5.1729 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.19716.19716.2 0.775 12-Jul K.LTFLDLR[166.11].N "sp|Q9H9A6|LRC40_HUMAN,tr|X6R5P2|X6R5P2_HUMAN" 2 886.5152 1.34 15657 19716 2 886.517409 444.2649 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.84 3710.3 - 554674 - - - 2.5222 - 1.541 0.16 - 200.8 1 2 0 0.0022 7 0 0 0 6.79E+06 5.06E+06 - - - 1.5922 0.9125 230117_WJC_METTL3_WT_vs_EV_F02.19717.19717.2 0.126 14-Sep L.IALALLAR.R sp|P43116|PE2R2_HUMAN 1 839.5593 999 15658 19717 2 839.560614 420.7869 Prostaglandin E2 receptor EP2 subtype OS=Homo sapiens OX=9606 GN=PTGER2 PE=1 SV=2 9.75 3710.4 - 533952 - - - 1.5973 - 1.885 0.17 - 378.1 1 1 0 0.0013 8 0 0 0 5.19E+06 0.00E+00 - - - 2.2081 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.19719.19719.2 3.59E-06 20-Oct R.VAQFLVIYAPR[166.11].R sp|Q9H2M9|RBGPR_HUMAN 1 1285.7422 1.59 15660 19719 2 1285.742613 643.8784 Rab3 GTPase-activating protein non-catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP2 PE=1 SV=1 8.72 3710.6 - 514979 - - - 0.3111 - 2.339 0.231 - 485.5 1 2 0 0.0004 11 0 0 0 4.00E+06 2.51E+06 - - - 3.0457 0.9952 230117_WJC_METTL3_WT_vs_EV_F02.19720.19720.2 0.0385 16-Aug R.VLLPVLLNK[136.11].N sp|O00186|STXB3_HUMAN 1 1015.6885 1.91 15661 19720 2 1015.691969 508.8515 Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2 8.72 3710.8 - 504413 - - - 3.4125 - 1.617 0.172 - 132.5 1 2 0 0.0035 9 0 0 0 6.41E+06 3.35E+06 - - - 1.7006 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.19722.19722.3 4.53E-08 14/40 R.MLIPYIEHWPR.A "sp|O75208|COQ9_HUMAN,tr|H3BPY0|H3BPY0_HUMAN,tr|H3BNT2|H3BNT2_HUMAN" 3 1453.754 2.81 15663 19722 3 1453.759527 485.592 "Ubiquinone biosynthesis protein COQ9, mitochondrial OS=Homo sapiens OX=9606 GN=COQ9 PE=1 SV=1" 6.5 3711 - 393298 - - - 3.7833 - 2.696 0.494 - 319.1 1 2 0 0.0055 11 0 0 0 1.49E+06 5.32E+05 - - - 6.8635 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19725.19725.2 0.000195 Jun-32 R.IQEIIEQLDVTTSEYEK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2037.0154 -1 15666 19725 2 2037.020607 1019.515 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3711.4 - 311241 - - - 2.565 - 1.792 0.45 - 77.9 1 2 0 0.0052 17 0 0 0 0.00E+00 0.00E+00 - - - 3.7972 0.9969 230117_WJC_METTL3_WT_vs_EV_F02.19727.19727.2 0.075 24-Sep K.ALLLVPASVNC[160.03]LR.L sp|Q5SRE5|NU188_HUMAN 1 1424.8174 -1 15667 19727 2 1424.817628 713.416 Nucleoporin NUP188 OS=Homo sapiens OX=9606 GN=NUP188 PE=1 SV=1 8.29 3711.7 - 435598 - - - 0.1909 - 1.787 0.142 - 228.8 1 2 0 0.0003 13 0 0 0 0.00E+00 0.00E+00 - - - 1.5797 1 230117_WJC_METTL3_WT_vs_EV_F02.19728.19728.2 1.01E-06 24-Sep R.LGIGMDTC[160.03]VIPLR.H "sp|P49903|SPS1_HUMAN,tr|Q5T5U6|Q5T5U6_HUMAN" 2 1443.7578 2.74 15668 19728 2 1443.758195 722.8862 "Selenide, water dikinase 1 OS=Homo sapiens OX=9606 GN=SEPHS1 PE=1 SV=2" 5.83 3711.9 - 0 - - - 0.2791 - 2.211 0.512 - 199.9 1 2 0 0.0004 13 0 0 0 1.47E+06 5.37E+05 - - - 4.8589 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19730.19730.2 0.000802 14-Aug R.NYFGLFPR.V sp|Q8WUF5|IASPP_HUMAN 1 1012.5131 2.28 15670 19730 2 1012.513742 507.2638 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.75 3712 - 2.70E+06 - - - 0.6825 - 1.411 0.426 - 286.4 1 2 0 0.0007 8 0 0 0 1.39E+07 6.09E+06 - - - 3.2256 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.19732.19732.2 0.043 12-Aug K.NFGIWLR[166.11].Y "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 914.5002 0.74 15672 19732 2 914.500978 458.2574 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 9.75 3712.1 - 2.22E+06 - - - 0.8595 - 1.661 0.25 - 331.6 1 2 0 0.0008 7 0 0 0 1.25E+08 1.69E+08 - - - 2.495 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19733.19733.2 0.0098 16-Sep K.LQLSLADFR.R "sp|O00541|PESC_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 2 1061.5869 0.9 15673 19733 2 1061.588103 531.8007 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 5.84 3712.2 - 2.20E+06 - - - 1.0908 - 1.936 0.428 - 309.5 1 2 0 0.0012 9 0 0 0 9.47E+06 1.05E+07 - - - 4.1131 1 230117_WJC_METTL3_WT_vs_EV_F02.19735.19735.2 3.61E-08 26-Dec R.IMGIPEEEQMGLLR.V sp|P35579|MYH9_HUMAN 1 1614.8109 1.26 15675 19735 2 1614.81313 808.4128 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3712.3 - 1.34E+06 - - - 1.3506 - 2.485 0.642 - 328.3 1 2 0 0.0022 14 0 0 0 4.06E+06 3.22E+06 - - - 6.0664 1 230117_WJC_METTL3_WT_vs_EV_F02.19736.19736.2 1.23E-06 26-Aug R.IMGIPEEEQMGLLR[166.11].V sp|P35579|MYH9_HUMAN 1 1624.8192 1.26 15676 19736 2 1624.829787 813.4169 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3712.4 - 1.73E+06 - - - 6.5041 - 1.862 0.544 - 143 1 2 0 0.0106 14 0 0 0 4.06E+06 3.22E+06 - - - 4.6157 1 230117_WJC_METTL3_WT_vs_EV_F02.19738.19738.2 3.56E-06 24-Nov K.IYVDDGLISLQVK[136.11].Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1469.8221 1.35 15678 19738 2 1469.822222 735.9183 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3712.5 - 1.22E+06 - - - 0.0857 - 2.264 0.509 - 301.1 1 2 0 0.0001 13 0 0 0 9.99E+06 7.42E+06 - - - 4.8976 1 230117_WJC_METTL3_WT_vs_EV_F02.19740.19740.2 0.000123 14/28 R.VMAGALEGDIFIGPK.A "sp|P61163|ACTZ_HUMAN,sp|P42025|ACTY_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 4 1516.796 1.53 15680 19740 2 1516.795991 759.4053 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4.37 3712.7 - 986557 - - - 0.0264 - 2.68 0.537 - 588.2 1 2 0 0 15 0 0 0 1.75E+07 1.14E+07 - - - 5.4309 0.9963 230117_WJC_METTL3_WT_vs_EV_F02.19741.19741.2 0.0371 14-Jun R.NYFGLFPR[166.11].V sp|Q8WUF5|IASPP_HUMAN 1 1022.5213 2.28 15681 19741 2 1022.51969 512.2679 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.75 3712.7 - 956696 - - - -1.5951 - 1.265 0.365 - 91.9 1 2 0 -0.0016 8 0 0 0 1.42E+07 6.23E+06 - - - 2.4453 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19742.19742.2 0.312 14-Sep K.LLILALER[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 949.62 1.28 15682 19742 2 949.620605 475.8173 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6 3712.8 - 788149 - - - 0.6655 - 1.893 0.248 - 313.3 1 2 0 0.0006 8 0 0 0 4.08E+07 3.19E+07 - - - 2.7972 1 230117_WJC_METTL3_WT_vs_EV_F02.19743.19743.2 5.06E-05 14/24 K.LLC[160.03]DSVVLQPYLR.E "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN,tr|H0YBB4|H0YBB4_HUMAN" 3 1574.8491 2.85 15683 19743 2 1574.851005 788.4318 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.83 3713 - 683540 - - - 1.2414 - 2.71 0.57 - 821.1 1 2 0 0.002 13 0 0 0 4.24E+06 1.49E+06 - - - 5.8091 1 230117_WJC_METTL3_WT_vs_EV_F02.19744.19744.2 0.00154 20-Sep R.LFEAEAQDLFR.D sp|Q9H223|EHD4_HUMAN 1 1337.6616 2.37 15684 19744 2 1337.663182 669.8381 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3713.1 - 637630 - - - 1.2081 - 2.23 0.459 - 269.7 1 2 0 0.0016 11 0 0 0 3.03E+07 1.28E+07 - - - 4.6003 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19748.19748.2 0.000596 18-Nov K.VAEITELILK[136.11].A "sp|Q06265|EXOS9_HUMAN,tr|D6R905|D6R905_HUMAN,tr|H0Y9L5|H0Y9L5_HUMAN,tr|D6RIY6|D6RIY6_HUMAN" 4 1135.6944 1.19 15687 19748 2 1135.695309 568.8545 Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3 4.53 3713.5 - 289415 - - - 0.8215 - 2.05 0.396 - 281.4 1 2 0 0.0009 10 0 0 0 2.01E+07 1.69E+07 - - - 3.9693 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.19752.19752.2 0.0602 18-Oct R.TLLLDGNPFR.V sp|Q9H9A6|LRC40_HUMAN 1 1144.6241 0.7 15691 19752 2 1144.621705 573.3193 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.5 3713.9 - 935503 - - - -2.0557 - 2.012 0.394 - 387.7 1 2 0 -0.0024 10 0 0 0 1.70E+07 2.44E+07 - - - 3.9018 1 230117_WJC_METTL3_WT_vs_EV_F02.19753.19753.2 2.11E-09 19/24 K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 0.33 15692 19753 2 1600.743975 801.3794 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3714 - 526587 - - - -0.2093 - 2.95 0.663 - 1322.2 1 2 0 -0.0003 13 0 0 0 1.02E+07 3.05E+07 - - - 6.7143 1 230117_WJC_METTL3_WT_vs_EV_F02.19755.19755.2 0.000791 20-Dec R.LFEAEAQDLFR[166.11].D sp|Q9H223|EHD4_HUMAN 1 1347.6698 2.37 15694 19755 2 1347.668236 674.8422 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3714.2 - 479573 - - - -1.1872 - 2.522 0.48 - 514.4 1 2 0 -0.0016 11 0 0 0 3.03E+07 1.28E+07 - - - 5.0883 0.9258 230117_WJC_METTL3_WT_vs_EV_F02.19757.19757.2 0.00269 18-Aug G.MEELIPLVNK.L sp|P50570|DYN2_HUMAN 1 1184.6475 1.15 15696 19757 2 1184.650819 593.331 Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2 4.53 3714.5 - 303066 - - - 2.8051 - 1.619 0.346 - 154.9 1 1 0 0.0033 10 0 0 0 3.80E+06 3.31E+06 - - - 2.9404 1 230117_WJC_METTL3_WT_vs_EV_F02.19758.19758.2 1.44E-06 13/22 K.YGLEGTVFFEEK[136.11].D "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1425.6907 3.04 15697 19758 2 1425.690984 713.8527 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.25 3714.6 - 288691 - - - 0.1655 - 2.351 0.558 - 351.1 1 2 0 0.0002 12 0 0 0 6.75E+06 2.22E+06 - - - 5.4115 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.19759.19759.2 0.133 16-Aug K.LFSNVLILK.S "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1045.6536 1.24 15698 19759 2 1045.654691 523.8341 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.75 3714.7 - 263332 - - - 1.074 - 1.663 0.256 - 126.8 2 2 0 0.0011 9 0 0 0 9.56E+06 7.72E+06 - - - 2.2685 0.9957 230117_WJC_METTL3_WT_vs_EV_F02.19765.19765.2 0.00769 12-Jul K.NFGIWLR.Y "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 904.4919 0.74 15703 19765 2 904.492364 453.2532 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 9.75 3715.3 - 3.39E+06 - - - 0.4887 - 1.518 0.115 - 277.4 1 2 0 0.0004 7 0 0 0 1.25E+08 1.69E+08 - - - 1.2128 1 230117_WJC_METTL3_WT_vs_EV_F02.19766.19766.2 2.95E-05 18-Oct K.LLDEVFFSEK.L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1225.6231 1.66 15704 19766 2 1225.624525 613.8188 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3715.3 - 422126 - - - 1.1994 - 1.834 0.54 - 287.6 1 2 0 0.0015 10 0 0 0 2.12E+08 1.28E+08 - - - 4.7219 1 230117_WJC_METTL3_WT_vs_EV_F02.19769.19769.2 1.55E-05 18-Oct K.LLDEVFFSEK[136.11].L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1233.6373 1.66 15705 19769 2 1233.639302 617.8259 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3715.8 - 9.24E+06 - - - 1.6593 - 2.177 0.47 - 269.6 1 2 0 0.002 10 0 0 0 2.12E+08 1.28E+08 - - - 4.6833 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19770.19770.2 5.11E-05 24-Oct K.IYVDDGLISLQVK.Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1461.8079 1.24 15706 19770 2 1461.809117 731.9112 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3715.8 - 3.06E+06 - - - 0.8353 - 1.981 0.421 - 221.5 1 2 0 0.0012 13 0 0 0 9.99E+06 8.03E+06 - - - 3.9046 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.19771.19771.2 0.00961 14-Sep R.NLFEQLVR.R "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VV47|F8VV47_HUMAN,tr|F8VUW9|F8VUW9_HUMAN,tr|F8VWY4|F8VWY4_HUMAN,tr|F8VRD2|F8VRD2_HUMAN,tr|F8VVY0|F8VVY0_HUMAN,tr|F8VZ66|F8VZ66_HUMAN,tr|F8VWX0|F8VWX0_HUMAN,tr|F8VS54|F8VS54_HUMAN,tr|F8W0L1|F8W0L1_HUMAN,tr|F8VVE5|F8VVE5_HUMAN,tr|F8VV39|F8VV39_HUMAN,tr|F8VXH1|F8VXH1_HUMAN" 13 1017.5607 2.52 15707 19771 2 1017.561822 509.7876 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 6 3715.9 - 4.50E+06 - - - 1.0732 - 1.517 0.252 - 324.6 1 2 0 0.0011 8 0 0 0 9.86E+06 3.92E+06 - - - 2.1588 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19772.19772.2 0.0225 16-Sep K.LFSNVLILK[136.11].S "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1053.6678 1.24 15708 19772 2 1053.669774 527.8412 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.75 3716 - 3.74E+06 - - - 1.9038 - 1.428 0.364 - 181.8 1 2 0 0.002 9 0 0 0 9.56E+06 7.72E+06 - - - 2.7596 1 230117_WJC_METTL3_WT_vs_EV_F02.19773.19773.2 2.67E-07 14/22 K.ALEDAFLAIDAK.L sp|O15355|PPM1G_HUMAN 1 1275.6711 2.29 15709 19773 2 1275.67302 638.8428 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.03 3716.1 - 3.08E+06 - - - 1.5302 - 2.701 0.541 - 587.9 1 2 0 0.002 12 0 0 0 3.12E+07 1.36E+07 - - - 5.6506 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19775.19775.2 0.000803 18-Sep R.C[160.03]LFQSPLFAK[136.11].A sp|Q86X55|CARM1_HUMAN 1 1217.6358 1.51 15711 19775 2 1217.635905 609.8252 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 8.22 3716.2 - 2.73E+06 - - - 0.0731 - 1.654 0.44 - 204.7 1 2 0 0.0001 10 0 0 0 1.04E+07 6.89E+06 - - - 3.6954 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.19776.19776.2 0.0913 16-Jul K.VIPTLALLK[136.11].D sp|O14530|TXND9_HUMAN 1 974.662 2.14 15712 19776 2 974.662377 488.3383 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 8.72 3716.4 - 2.72E+06 - - - 0.434 - 1.045 0.289 - 76.7 1 2 0 0.0004 9 0 0 0 1.17E+07 5.47E+06 - - - 1.3028 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19778.19778.2 0.00562 16-Sep K.TLFPLIEAK[136.11].K sp|P13010|XRCC5_HUMAN 1 1038.6205 1.02 15714 19778 2 1038.622365 520.3175 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.66 3716.5 - 2.50E+06 - - - 1.812 - 1.479 0.34 - 240.6 1 2 0 0.0019 9 0 0 0 4.54E+08 4.46E+08 - - - 2.6839 0.9683 230117_WJC_METTL3_WT_vs_EV_F02.19780.19780.2 0.00972 16-Oct V.TLLAAEFLK.Q "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 1004.5906 6.17 15716 19780 2 1004.591465 503.3026 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 5.66 3716.8 - 2.01E+06 - - - 0.8282 - 1.693 0.413 - 267.9 1 1 0 0.0008 9 0 0 0 3.82E+06 6.19E+05 - - - 3.6144 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.19782.19782.2 0.75 14-Jul K.SLLAGLLK[136.11].K "sp|P31751|AKT2_HUMAN,tr|M0R0P9|M0R0P9_HUMAN,tr|J3QKW1|J3QKW1_HUMAN,tr|J3QL45|J3QL45_HUMAN,tr|M0R283|M0R283_HUMAN,tr|M0QZW8|M0QZW8_HUMAN" 6 821.5466 0.86 15718 19782 2 821.547245 411.7806 RAC-beta serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=AKT2 PE=1 SV=2 8.47 3717 - 1.70E+06 - - - 0.7973 - 1.25 0.204 - 158.3 1 2 0 0.0007 8 0 0 0 2.93E+06 3.39E+06 - - - 1.2205 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19784.19784.2 0.000459 24-Oct R.GLLPGLLPAPADK[136.11].L sp|Q6P2E9|EDC4_HUMAN 1 1268.7584 1.81 15720 19784 2 1268.760654 635.3865 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 5.84 3717.2 - 1.58E+06 - - - 1.797 - 2.127 0.228 - 322.4 1 2 0 0.0023 13 0 0 0 5.90E+06 3.27E+06 - - - 2.6613 0.9936 230117_WJC_METTL3_WT_vs_EV_F02.19785.19785.2 0.61 14-Aug K.SVWALLQR[166.11].N sp|Q5VUD6|DIK1B_HUMAN 1 981.5635 0.97 15721 19785 2 981.566471 491.789 Divergent protein kinase domain 1B OS=Homo sapiens OX=9606 GN=DIPK1B PE=1 SV=3 9.47 3717.4 - 1.38E+06 - - - 3.0064 - 1.413 0.158 - 167.1 1 2 0 0.0029 8 0 0 0 3.53E+06 3.64E+06 - - - 1.2497 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19791.19791.2 0.000621 16-Oct K.TLFPLIEAK.K sp|P13010|XRCC5_HUMAN 1 1030.6063 1.02 15726 19791 2 1030.609072 516.3104 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.66 3718 - 4.12E+06 - - - 2.7062 - 1.546 0.379 - 296.5 1 2 0 0.0028 9 0 0 0 4.53E+08 4.45E+08 - - - 3.0998 0.9866 230117_WJC_METTL3_WT_vs_EV_F02.19796.19796.2 0.0142 14-Oct R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 10.09 15731 19796 2 1000.566961 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3718.5 - 576904 - - - 7.6237 - 2.274 0.293 - 329.6 1 2 0 0.0076 8 0 0 0 8.33E+06 8.26E+05 - - - 3.6804 1 230117_WJC_METTL3_WT_vs_EV_F02.19797.19797.2 1.03E-05 13/20 R.EVWALVQAGIR.D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1240.6928 1.56 15732 19797 2 1240.696169 621.3537 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.1 3718.6 - 514745 - - - 2.7098 - 2.595 0.48 - 646.5 1 2 0 0.0034 11 0 0 0 1.68E+07 1.08E+07 - - - 5.1649 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19798.19798.2 4.80E-05 20-Oct R.EYIDYEFSVLK.E "sp|Q8IZH2|XRN1_HUMAN,tr|C9JCZ8|C9JCZ8_HUMAN" 2 1404.6813 -1 15733 19798 2 1404.680893 703.3479 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.14 3718.7 - 479466 - - - -0.289 - 1.839 0.473 - 296.6 1 2 0 -0.0004 11 0 0 0 0.00E+00 0.00E+00 - - - 4.1825 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19801.19801.2 0.000143 13/22 R.TFLESPLDVGIK.L "sp|Q8TEU7|RPGF6_HUMAN,tr|B7Z7Y1|B7Z7Y1_HUMAN,tr|E9PCH4|E9PCH4_HUMAN,tr|D6RE77|D6RE77_HUMAN,tr|A0A5F9ZHG7|A0A5F9ZHG7_HUMAN" 5 1317.718 0.09 15736 19801 2 1317.722751 659.8663 Rap guanine nucleotide exchange factor 6 OS=Homo sapiens OX=9606 GN=RAPGEF6 PE=1 SV=2 4.37 3719.1 - 312172 - - - 3.5918 - 2.275 0.38 - 456.1 1 2 0 0.0047 12 0 0 0 5.25E+07 5.94E+08 - - - 4.009 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19803.19803.2 0.00392 12-Jul K.DAFLVFR[166.11].S "sp|Q9Y6D6|BIG1_HUMAN,sp|Q9Y6D5|BIG2_HUMAN,tr|A0A7P0T7Z2|A0A7P0T7Z2_HUMAN,tr|A0A7P0T9L9|A0A7P0T9L9_HUMAN,tr|A0A7P0TA34|A0A7P0TA34_HUMAN,tr|A0A7P0T9L6|A0A7P0T9L6_HUMAN" 6 876.4733 1.61 15738 19803 2 876.474926 439.2439 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens OX=9606 GN=ARFGEF1 PE=1 SV=2 5.84 3719.4 - 238462 - - - 1.846 - 1.61 0.351 - 198.7 1 2 0 0.0016 7 0 0 0 3.78E+06 2.36E+06 - - - 3.142 1 230117_WJC_METTL3_WT_vs_EV_F02.19810.19810.2 6.23E-07 14/22 R.IYGLGSLALYEK[136.11].A sp|P36542|ATPG_HUMAN 1 1333.7373 1.6 15744 19810 2 1333.739911 667.8759 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6 3720.2 - 2.18E+06 - - - 1.9547 - 2.694 0.493 - 515.1 1 2 0 0.0026 12 0 0 0 6.09E+08 3.80E+08 - - - 5.289 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19811.19811.2 0.00138 18-Oct K.SVLIGEFLEK[136.11].V "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1141.6474 0.91 15745 19811 2 1141.648681 571.831 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 3720.3 - 676115 - - - 1.0993 - 1.965 0.454 - 344.6 1 2 0 0.0013 10 0 0 0 1.82E+08 2.00E+08 - - - 4.2794 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19812.19812.2 0.00202 18-Oct K.SVLIGEFLEK.V "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1133.6332 0.91 15746 19812 2 1133.634164 567.8239 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 3720.4 - 574998 - - - 0.8274 - 2.096 0.452 - 351.9 1 2 0 0.0009 10 0 0 0 1.82E+08 1.99E+08 - - - 4.4448 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.19815.19815.2 0.00274 18-Sep K.ELLGQGLLLR[166.11].S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1120.6844 0.9 15749 19815 2 1120.689642 561.3495 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3720.8 - 255298 - - - 4.7096 - 1.962 0.339 - 260.2 1 2 0 0.0053 10 0 0 0 2.75E+08 3.07E+08 - - - 3.4244 1 230117_WJC_METTL3_WT_vs_EV_F02.19816.19816.2 3.25E-06 15/22 K.ALEDAFLAIDAK[136.11].L sp|O15355|PPM1G_HUMAN 1 1283.6853 2.26 15750 19816 2 1283.689726 642.8499 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.03 3720.9 - 243377 - - - 3.4728 - 2.7 0.52 - 679.2 1 2 0 0.0045 12 0 0 0 3.12E+07 1.38E+07 - - - 5.4937 0.9965 230117_WJC_METTL3_WT_vs_EV_F02.19817.19817.2 0.132 14-Aug R.NIPMLFVR.G sp|P62310|LSM3_HUMAN 1 988.5528 2.48 15751 19817 2 988.555096 495.2837 U6 snRNA-associated Sm-like protein LSm3 OS=Homo sapiens OX=9606 GN=LSM3 PE=1 SV=2 9.75 3721.1 - 229670 - - - 2.3145 - 1.295 0.219 - 193.4 1 2 0 0.0023 8 0 0 0 6.07E+07 2.45E+07 - - - 1.4375 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.19818.19818.2 0.0195 18-Oct R.VDLPLAVLSK.M "sp|Q9H773|DCTP1_HUMAN,tr|H3BSA6|H3BSA6_HUMAN" 2 1053.6434 4.84 15752 19818 2 1053.640135 527.829 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 5.81 3721.2 - 139844 - - - -3.0959 - 2.104 0.423 - 227.4 1 2 0 -0.0033 10 0 0 0 8.91E+07 1.84E+07 - - - 4.2405 0.9852 230117_WJC_METTL3_WT_vs_EV_F02.19821.19821.2 0.459 16-Jun K.VIPTLALLK.D sp|O14530|TXND9_HUMAN 1 966.6478 2.16 15755 19821 2 966.648517 484.3312 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 8.72 3721.6 - 112122 - - - 0.7893 - 0.948 0.203 - 51.9 2 2 0 0.0008 9 0 0 0 1.18E+07 5.47E+06 - - - 0.2512 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.19825.19825.2 0.0033 18-Nov R.GPILLPYQFR[166.11].M "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1212.6894 0.87 15757 19825 2 1212.694649 607.352 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 8.75 3722.1 - 510742 - - - 4.288 - 2.274 0.359 - 518.5 1 2 0 0.0052 10 0 0 0 1.67E+07 1.93E+07 - - - 3.9841 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.19828.19828.3 0.00747 17/76 R.LALVTGGEIASTFDHPELVK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2096.1154 999 15760 19828 3 2096.113041 699.7124 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 3722.4 - 168870 - - - -1.1116 - 2.078 0.301 - 199.2 1 2 0 -0.0023 20 0 0 0 5.42E+06 0.00E+00 - - - 3.6696 1 230117_WJC_METTL3_WT_vs_EV_F02.19830.19830.2 0.00816 14-Oct K.IPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1059.5502 1.24 15761 19830 2 1059.550948 530.7824 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3722.7 - 1.21E+08 - - - 0.739 - 2.08 0.463 - 541.9 1 2 0 0.0008 8 0 0 0 6.65E+09 5.34E+09 - - - 4.6693 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19832.19832.2 0.0198 18-Sep K.ELLGQGLLLR.S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1110.6761 0.9 15762 19832 2 1110.677667 556.3453 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3722.9 - 2.00E+07 - - - 1.4163 - 2.013 0.317 - 315.6 1 2 0 0.0016 10 0 0 0 2.75E+08 3.07E+08 - - - 3.3347 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.19833.19833.2 0.179 14-Jul R.LSLELFGR.V "sp|O95071|UBR5_HUMAN,tr|E5RFK7|E5RFK7_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 933.5284 1.92 15763 19833 2 933.529351 467.7715 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 6 3723 - 4.36E+06 - - - 1.0541 - 1.571 0.238 - 125 1 2 0 0.001 8 0 0 0 4.11E+07 2.14E+07 - - - 2.1609 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.19834.19834.2 0.00999 20-Oct R.VLLQAFDVVER[166.11].S sp|Q15750|TAB1_HUMAN 1 1297.727 0.49 15764 19834 2 1297.726428 649.8708 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 OS=Homo sapiens OX=9606 GN=TAB1 PE=1 SV=1 4.37 3723.1 - 3.73E+06 - - - -0.4076 - 2.175 0.23 - 328.6 2 2 0 -0.0005 11 0 0 0 3.14E+07 6.43E+07 - - - 2.7072 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.19835.19835.2 0.046 14-Jul R.LSLELFGR[166.11].V "sp|O95071|UBR5_HUMAN,tr|E5RFK7|E5RFK7_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 943.5366 1.91 15765 19835 2 943.5371 472.7756 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 6 3723.2 - 2.96E+06 - - - 0.4907 - 1.604 0.164 - 144 1 2 0 0.0005 8 0 0 0 4.11E+07 2.15E+07 - - - 1.6772 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.19836.19836.2 0.00206 14/22 K.LANILFTQELAR.R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1387.7823 1.33 15766 19836 2 1387.780394 694.8985 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3723.4 - 2.11E+06 - - - -1.4094 - 2.997 0.298 - 892.8 1 2 0 -0.002 12 0 0 0 5.87E+07 4.42E+07 - - - 4.1294 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19837.19837.2 0.00487 20-Oct K.ALLLSSVLSEK.G "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1158.686 2.59 15767 19837 2 1158.689001 580.3503 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 6.05 3723.5 - 1.60E+06 - - - 2.5986 - 2.225 0.32 - 273.7 1 2 0 0.003 11 0 0 0 2.57E+07 9.92E+06 - - - 3.5671 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19838.19838.2 0.00049 18-Oct K.QLEDILVLAK[136.11].Q "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A0A6YYJ5|A0A0A6YYJ5_HUMAN" 8 1148.6896 2.89 15768 19838 2 1148.68982 575.3521 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.37 3723.6 - 1.50E+06 - - - 0.1698 - 1.915 0.339 - 249.9 1 2 0 0.0002 10 0 0 0 3.33E+07 1.15E+07 - - - 3.3584 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19841.19841.2 0.00239 20-Aug K.IESLPPLLIGK[136.11].F "sp|Q8N9N7|LRC57_HUMAN,tr|A0A3B3ISV5|A0A3B3ISV5_HUMAN,tr|H3BSW0|H3BSW0_HUMAN" 3 1186.7417 2.25 15771 19841 2 1186.743312 594.3781 Leucine-rich repeat-containing protein 57 OS=Homo sapiens OX=9606 GN=LRRC57 PE=1 SV=1 6 3724 - 1.20E+06 - - - 1.3912 - 1.551 0.458 - 141.4 1 2 0 0.0017 11 0 0 0 1.86E+07 8.27E+06 - - - 3.6106 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.19843.19843.2 0.468 14-Nov R.LAWALALR[166.11].G sp|Q92621|NU205_HUMAN 1 922.5628 2.42 15773 19843 2 922.564164 462.2887 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 9.75 3724.3 - 891145 - - - 1.4872 - 1.607 0.203 - 388.4 1 2 0 0.0014 8 0 0 0 9.76E+06 4.03E+06 - - - 1.9706 0.9897 230117_WJC_METTL3_WT_vs_EV_F02.19844.19844.2 0.203 12-May K.DAFLVFR.S "sp|Q9Y6D6|BIG1_HUMAN,sp|Q9Y6D5|BIG2_HUMAN,tr|A0A7P0T7Z2|A0A7P0T7Z2_HUMAN,tr|A0A7P0T9L9|A0A7P0T9L9_HUMAN,tr|A0A7P0TA34|A0A7P0TA34_HUMAN,tr|A0A7P0T9L6|A0A7P0T9L6_HUMAN" 6 866.465 1.61 15774 19844 2 866.464843 434.2398 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens OX=9606 GN=ARFGEF1 PE=1 SV=2 5.84 3724.4 - 751672 - - - -0.2251 - 1.19 0.166 - 74 1 2 0 -0.0002 7 0 0 0 3.78E+06 2.36E+06 - - - 0.8182 0.999 230117_WJC_METTL3_WT_vs_EV_F02.19846.19846.2 0.366 20-Aug K.ALLLSSVLSEK[136.11].G "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1166.7002 2.59 15776 19846 2 1166.702121 584.3574 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 6.05 3724.6 - 598421 - - - 1.6551 - 1.897 0.222 - 125 1 2 0 0.0019 11 0 0 0 2.57E+07 9.92E+06 - - - 2.4122 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19851.19851.2 0.00784 15/22 K.LANILFTQELAR[166.11].R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1397.7906 1.33 15779 19851 2 1397.792018 699.9026 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3725.2 - 3.45E+06 - - - 1.0001 - 2.714 0.299 - 1018.2 1 2 0 0.0014 12 0 0 0 5.86E+07 4.42E+07 - - - 3.876 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.19852.19852.2 0.00836 16-Aug R.ILDTLGLLR[166.11].Q "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN,tr|A0A087WWF4|A0A087WWF4_HUMAN" 3 1022.6364 1.07 15780 19852 2 1022.638676 512.3255 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 5.84 3725.3 - 1.76E+06 - - - 2.2735 - 1.715 0.326 - 153.5 1 2 0 0.0023 9 0 0 0 4.41E+07 4.12E+07 - - - 3.0087 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19856.19856.2 0.00181 16-Sep R.ILDTLGLLR.Q "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN,tr|A0A087WWF4|A0A087WWF4_HUMAN" 3 1012.6281 1.07 15784 19856 2 1012.628657 507.3213 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 5.84 3725.6 - 1.89E+06 - - - 0.5688 - 2.039 0.337 - 202.1 1 2 0 0.0006 9 0 0 0 4.41E+07 4.12E+07 - - - 3.5911 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19858.19858.2 0.104 14-Aug R.MGLLAVLR.S "sp|O95394|AGM1_HUMAN,tr|D6RF77|D6RF77_HUMAN,tr|D6RC77|D6RC77_HUMAN,tr|D6RCQ8|D6RCQ8_HUMAN,tr|A0A494C099|A0A494C099_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C163|A0A494C163_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|D6RCD1|D6RCD1_HUMAN" 9 871.5313 1.65 15786 19858 2 871.531885 436.7729 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 9.5 3725.8 - 957000 - - - 0.6207 - 1.824 0.322 - 211.8 1 2 0 0.0005 8 0 0 0 8.85E+06 5.37E+06 - - - 3.2318 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19859.19859.2 0.00537 20-Oct K.SFYGSTLFLC[160.03]R[166.11].R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1359.6521 1.52 15787 19859 2 1359.654656 680.8333 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 7.94 3726 - 755241 - - - 1.8961 - 1.787 0.367 - 345.2 1 2 0 0.0026 11 0 0 0 1.26E+07 8.26E+06 - - - 3.3213 0.9962 230117_WJC_METTL3_WT_vs_EV_F02.19860.19860.2 0.0144 18-Sep K.NIFSVPEIVR.E "sp|O60645|EXOC3_HUMAN,tr|D6RB59|D6RB59_HUMAN" 2 1172.6554 2.33 15788 19860 2 1172.655066 587.335 Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3 6 3726.1 - 570951 - - - -0.2499 - 1.544 0.184 - 233.4 1 2 0 -0.0003 10 0 0 0 1.30E+07 5.60E+06 - - - 1.6124 0.9706 230117_WJC_METTL3_WT_vs_EV_F02.19864.19864.2 0.47 24-Jul R.TLVSGLLLEDSVR[166.11].V sp|A0A2Z4LIS9|FXO3B_HUMAN 1 1410.7958 0.37 15792 19864 2 1410.794439 706.4052 Forkhead box protein O3B OS=Homo sapiens OX=9606 GN=FOXO3B PE=1 SV=1 4.37 3726.6 - 514062 - - - -0.9399 - 1.438 0.073 - 150.8 2 2 0 -0.0013 13 0 0 0 2.43E+06 6.62E+06 - - - 0.3776 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19868.19868.2 0.00454 14-Aug K.IPDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1069.5584 1.24 15794 19868 2 1069.558555 535.7865 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3727.1 - 6.07E+08 - - - 0.1122 - 1.65 0.489 - 368.8 1 2 0 0.0001 8 0 0 0 6.65E+09 5.34E+09 - - - 4.163 0.9015 230117_WJC_METTL3_WT_vs_EV_F02.19870.19870.2 0.0143 12-Aug L.PDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 946.4661 1.27 15796 19870 2 946.464479 474.2403 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 6.27 3727.3 - 4.10E+06 - - - -1.7137 - 1.784 0.42 - 280.1 1 1 0 -0.0016 7 0 0 0 4.17E+07 3.29E+07 - - - 3.9768 1 230117_WJC_METTL3_WT_vs_EV_F02.19871.19871.2 1.97E-05 20-Dec K.SFYGSTLFLC[160.03]R.R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1349.6438 1.52 15797 19871 2 1349.645851 675.8292 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 7.94 3727.4 - 2.12E+06 - - - 1.5137 - 2.348 0.541 - 470.9 1 2 0 0.002 11 0 0 0 1.26E+07 8.26E+06 - - - 5.3453 0.9191 230117_WJC_METTL3_WT_vs_EV_F02.19873.19873.3 0.197 Oct-48 R.GAAGALLVYDITR.R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1318.7245 1.38 15799 19873 3 1318.727227 440.5821 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3727.7 - 1.15E+06 - - - 2.0671 - 1.579 0.064 - 168 4 2 0 0.0027 13 0 0 0 7.43E+06 5.39E+06 - - - 0.2126 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19875.19875.3 0.00814 Sep-36 K.LTLLTLHFPR.L "sp|Q92889|XPF_HUMAN,tr|A0A804HKF9|A0A804HKF9_HUMAN" 2 1209.7234 2.56 15801 19875 3 1209.723848 404.2484 DNA repair endonuclease XPF OS=Homo sapiens OX=9606 GN=ERCC4 PE=1 SV=3 9.76 3727.9 - 0 - - - 0.3877 - 2.013 0.306 - 78.2 1 2 0 0.0005 10 0 0 0 4.19E+06 1.64E+06 - - - 3.9947 1 230117_WJC_METTL3_WT_vs_EV_F02.19878.19878.2 6.77E-05 13/22 K.IYDALDVSLIER[166.11].G sp|P54136|SYRC_HUMAN 1 1415.7536 1.5 15802 19878 2 1415.752137 708.8841 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.03 3728.3 - 1.61E+06 - - - -1.0094 - 2.696 0.577 - 699.1 1 2 0 -0.0014 12 0 0 0 4.08E+07 2.73E+07 - - - 5.9118 0.9802 230117_WJC_METTL3_WT_vs_EV_F02.19883.19883.2 0.218 20-Sep K.LIAELWDSGIK[136.11].A "sp|P49590|SYHM_HUMAN,tr|A0A2R8Y5P7|A0A2R8Y5P7_HUMAN,tr|A0A2R8Y6I1|A0A2R8Y6I1_HUMAN,tr|B4DQ67|B4DQ67_HUMAN,tr|D6RB22|D6RB22_HUMAN,tr|A0A2R8Y3N3|A0A2R8Y3N3_HUMAN" 6 1251.6954 0.001 15807 19883 2 1251.691883 626.855 "Histidine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=HARS2 PE=1 SV=1" 4.37 3728.9 - 290889 - - - -2.8409 - 1.548 0.186 - 212 1 2 0 -0.0036 11 0 0 0 0.00E+00 9.04E+06 - - - 1.5958 1 230117_WJC_METTL3_WT_vs_EV_F02.19884.19884.2 0.00141 22-Dec R.LFSNFSGADLLK.L "sp|Q9NZI7|UBIP1_HUMAN,tr|F8WEP8|F8WEP8_HUMAN" 2 1310.6871 3.79 15808 19884 2 1310.688618 656.3508 Upstream-binding protein 1 OS=Homo sapiens OX=9606 GN=UBP1 PE=1 SV=1 5.84 3729 - 340620 - - - 1.194 - 2.519 0.456 - 321.2 1 2 0 0.0016 12 0 0 0 9.77E+06 2.58E+06 - - - 4.8394 0.9695 230117_WJC_METTL3_WT_vs_EV_F02.19887.19887.2 0.0276 12-Sep L.PDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 956.4744 1.27 15809 19887 2 956.474719 479.2445 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 6.27 3729.4 - 1.79E+06 - - - 0.3638 - 1.847 0.405 - 333.4 1 1 0 0.0003 7 0 0 0 4.17E+07 3.29E+07 - - - 3.9763 0.9875 230117_WJC_METTL3_WT_vs_EV_F02.19888.19888.2 1.3 18-Jul R.FPPVVFYTPK.E "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1193.6485 1.2 15810 19888 2 1193.649045 597.8315 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3729.6 - 349515 - - - 0.4717 - 1.105 0.151 - 85.1 1 2 0 0.0006 10 0 0 0 6.10E+06 5.06E+06 - - - 0.4348 1 230117_WJC_METTL3_WT_vs_EV_F02.19889.19889.2 0.000541 14/22 K.IYDALDVSLIER.G sp|P54136|SYRC_HUMAN 1 1405.7453 1.5 15811 19889 2 1405.744127 703.8799 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.03 3729.7 - 2.31E+06 - - - -0.8316 - 2.709 0.601 - 776.5 1 2 0 -0.0012 12 0 0 0 4.08E+07 2.73E+07 - - - 6.1018 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.19890.19890.2 0.0503 18-Sep R.NVEELVIVLK.K "sp|P53618|COPB_HUMAN,tr|E9PP73|E9PP73_HUMAN" 2 1154.6911 3.2 15812 19890 2 1154.691037 578.3528 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 4.53 3729.8 - 732648 - - - -0.0329 - 1.76 0.227 - 191.6 1 2 0 0 10 0 0 0 1.55E+07 4.86E+06 - - - 2.2956 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19891.19891.2 0.000505 13/22 K.IDVLQAEVAALK.T "sp|Q96QF0|RAB3I_HUMAN,tr|H0YI02|H0YI02_HUMAN,tr|J3KPG1|J3KPG1_HUMAN" 3 1268.734 3.99 15813 19891 2 1268.734892 635.3743 Rab-3A-interacting protein OS=Homo sapiens OX=9606 GN=RAB3IP PE=1 SV=1 4.37 3729.9 - 616549 - - - 0.7007 - 2.207 0.381 - 447.7 1 2 0 0.0009 12 0 0 0 2.09E+07 5.24E+06 - - - 3.9377 1 230117_WJC_METTL3_WT_vs_EV_F02.19892.19892.2 0.00652 13/24 R.LLLFSSATDAAIR.V "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1376.7664 0.31 15814 19892 2 1376.764604 689.3905 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.84 3730.1 - 472633 - - - -1.2798 - 2.838 0.504 - 583 1 2 0 -0.0018 13 0 0 0 1.28E+07 4.17E+07 - - - 5.4401 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19893.19893.2 0.00114 22-Nov K.YLGPAVLMQAYR.W sp|P21912|SDHB_HUMAN 1 1380.7224 1.87 15815 19893 2 1380.724989 691.3685 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 8.59 3730.2 - 426568 - - - 1.8809 - 1.946 0.441 - 369 1 2 0 0.0026 12 0 0 0 5.33E+06 2.85E+06 - - - 4.0492 0.9947 230117_WJC_METTL3_WT_vs_EV_F02.19894.19894.2 0.0259 20-Dec R.ASEAVLWEALR.K "sp|Q9Y5V3|MAGD1_HUMAN,sp|Q96JG8|MAGD4_HUMAN" 2 1243.6561 16.41 15816 19894 2 1243.651563 622.8353 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 4.53 3730.3 - 396468 - - - -3.6377 - 1.978 0.379 - 417.1 1 2 0 -0.0045 11 0 0 0 1.48E+07 9.00E+05 - - - 3.6841 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.19895.19895.2 0.000814 24-Sep R.LVDIIAAVPPQYR.K "sp|Q9H9T3|ELP3_HUMAN,tr|E5RIZ7|E5RIZ7_HUMAN,tr|E5RIC0|E5RIC0_HUMAN,tr|E5RHY2|E5RHY2_HUMAN,tr|E5RHR2|E5RHR2_HUMAN" 5 1453.8293 1.8 15817 19895 2 1453.828349 727.9219 Elongator complex protein 3 OS=Homo sapiens OX=9606 GN=ELP3 PE=1 SV=2 5.84 3730.5 - 252046 - - - -0.6541 - 2.303 0.39 - 297.1 1 2 0 -0.001 13 0 0 0 1.08E+07 6.01E+06 - - - 4.0623 0.9919 230117_WJC_METTL3_WT_vs_EV_F02.19899.19899.2 0.139 12-Jul K.LLDDLFR[166.11].K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 900.4944 0.98 15819 19899 2 900.493165 451.2545 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3731 - 411940 - - - -1.4137 - 1.327 0.224 - 131.2 1 2 0 -0.0013 7 0 0 0 2.49E+08 2.55E+08 - - - 1.5915 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.19900.19900.2 0.00346 13/20 R.NAVLAIYTIYR.N "sp|P53618|COPB_HUMAN,tr|E9PP73|E9PP73_HUMAN" 2 1295.7238 4.07 15820 19900 2 1295.722865 648.8692 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 8.59 3731.1 - 345911 - - - -0.7 - 2.475 0.331 - 671.4 1 2 0 -0.0009 11 0 0 0 6.10E+07 1.50E+07 - - - 3.9371 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19901.19901.2 8.79E-07 13/24 K.LDNLLLDTEGYVK.L "sp|Q16512|PKN1_HUMAN,tr|K7EL10|K7EL10_HUMAN" 2 1491.7821 2.11 15821 19901 2 1491.78094 746.8983 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 4.03 3731.2 - 0 - - - -0.7608 - 2.641 0.401 - 365 1 2 0 -0.0011 13 0 0 0 4.12E+06 1.96E+06 - - - 4.4949 1 230117_WJC_METTL3_WT_vs_EV_F02.19902.19902.2 0.00162 20-Dec R.ILVYLVQEINR[166.11].A "sp|Q9Y487|VPP2_HUMAN,tr|Q8TBM3|Q8TBM3_HUMAN,tr|A0A6Q8PFU6|A0A6Q8PFU6_HUMAN" 3 1368.8005 0.54 15822 19902 2 1368.800728 685.4075 V-type proton ATPase 116 kDa subunit a2 OS=Homo sapiens OX=9606 GN=ATP6V0A2 PE=1 SV=2 6 3731.4 - 0 - - - 0.1987 - 2.538 0.505 - 607.7 1 2 0 0.0003 11 0 0 0 2.44E+06 4.52E+06 - - - 5.2904 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.19903.19903.2 0.0105 24-Oct K.LDNLLLDTEGYVK[136.11].L "sp|Q16512|PKN1_HUMAN,tr|K7EL10|K7EL10_HUMAN" 2 1499.7963 -1 15823 19903 2 1499.801486 750.9054 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 4.03 3731.5 - 0 - - - 3.4745 - 1.922 0.284 - 311.1 1 2 0 0.0052 13 0 0 0 0.00E+00 0.00E+00 - - - 2.8139 0.9954 230117_WJC_METTL3_WT_vs_EV_F02.19907.19907.2 0.0587 12-Jul R.WLSQYID.- "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 923.4389 - 15825 19907 2 923.438821 462.7267 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.3 3732 - 4.99E+06 - - - -0.0671 - 1.203 0.237 - 119.3 1 2 0 -0.0001 7 0 0 0 - - - - - 1.3771 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.19908.19908.2 0.000247 18-Oct K.GIYLWDVEGR.K sp|P04181|OAT_HUMAN 1 1206.6033 1.46 15826 19908 2 1206.600708 604.3089 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.37 3732.1 - 2.46E+06 - - - -2.1672 - 1.986 0.481 - 351.5 1 2 0 -0.0026 10 0 0 0 1.11E+07 7.58E+06 - - - 4.508 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.19909.19909.2 0.0774 14-Jun R.NLIEWLNK[136.11].Y sp|Q96DG6|CMBL_HUMAN 1 1036.5797 0.9 15827 19909 2 1036.582207 519.2971 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 6 3732.2 - 2.39E+07 - - - 2.4369 - 1.401 0.264 - 128.3 1 2 0 0.0025 8 0 0 0 1.71E+08 1.90E+08 - - - 2.007 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.19910.19910.2 0.263 12-Jul K.LLDDLFR.K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 890.4862 0.98 15828 19910 2 890.486528 446.2504 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3732.2 - 1.34E+07 - - - 0.4043 - 1.454 0.147 - 167.1 1 2 0 0.0004 7 0 0 0 2.49E+08 2.54E+08 - - - 1.3127 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.19911.19911.2 0.0158 18-Aug K.IINFAPSLLR.L "sp|O15397|IPO8_HUMAN,tr|F5H2I3|F5H2I3_HUMAN" 2 1142.6812 1.27 15829 19911 2 1142.684087 572.3479 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 9.75 3732.3 - 1.18E+07 - - - 2.5449 - 2.043 0.386 - 154.9 1 2 0 0.0029 10 0 0 0 5.48E+07 4.31E+07 - - - 3.8852 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19912.19912.2 0.551 18-Aug K.IINFAPSLLR[166.11].L "sp|O15397|IPO8_HUMAN,tr|F5H2I3|F5H2I3_HUMAN" 2 1152.6894 1.27 15830 19912 2 1152.690409 577.352 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 9.75 3732.3 - 9.96E+06 - - - 0.8328 - 1.837 0.268 - 209.2 1 2 0 0.001 10 0 0 0 5.48E+07 4.31E+07 - - - 2.7176 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.19914.19914.2 0.0433 18-Aug R.LVLVNAVYFR.G "sp|P35237|SPB6_HUMAN,tr|A0A087X1N8|A0A087X1N8_HUMAN,tr|A0A2R8Y6A7|A0A2R8Y6A7_HUMAN,tr|A0A024QZX5|A0A024QZX5_HUMAN,tr|A0A2R8YD12|A0A2R8YD12_HUMAN" 5 1192.6968 0.38 15832 19914 2 1192.701695 597.3557 Serpin B6 OS=Homo sapiens OX=9606 GN=SERPINB6 PE=1 SV=3 8.75 3732.5 - 5.25E+06 - - - 4.0798 - 2.006 0.323 - 182.7 1 2 0 0.0049 10 0 0 0 1.01E+07 2.66E+07 - - - 3.3683 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19916.19916.2 1.38E-05 15/24 R.AGLNGLQLAVLAR.L sp|Q96S55|WRIP1_HUMAN 1 1294.7721 4.09 15834 19916 2 1294.772953 648.3933 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 9.79 3732.8 - 3.63E+06 - - - 0.6434 - 2.383 0.197 - 814.9 1 2 0 0.0008 13 0 0 0 1.17E+07 2.85E+06 - - - 2.7245 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19917.19917.2 0.00952 13/20 R.NAVLAIYTIYR[166.11].N "sp|P53618|COPB_HUMAN,tr|E9PP73|E9PP73_HUMAN" 2 1305.732 4.07 15835 19917 2 1305.736154 653.8733 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 8.59 3732.9 - 3.38E+06 - - - 3.1492 - 2.365 0.3 - 622.9 1 2 0 0.0041 11 0 0 0 6.10E+07 1.50E+07 - - - 3.5841 0.973 230117_WJC_METTL3_WT_vs_EV_F02.19918.19918.2 8.08E-05 22-Nov K.LLQVASPFLEPH.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1349.7343 - 15836 19918 2 1349.736798 675.8744 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 5.24 3733 - 2.36E+06 - - - 1.8233 - 1.774 0.456 - 332 1 1 0 0.0025 12 0 0 0 - - - - - 3.9165 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19922.19922.2 7.70E-05 24-Oct R.VETPVLPPVLVPR[166.11].H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1424.8631 1.61 15840 19922 2 1424.863607 713.4388 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3733.6 - 1.14E+06 - - - 0.386 - 1.943 0.444 - 242.8 1 2 0 0.0006 13 0 0 0 1.17E+07 7.27E+06 - - - 4.025 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19930.19930.2 0.0133 14-Nov R.NLIEWLNK.Y sp|Q96DG6|CMBL_HUMAN 1 1028.5655 0.9 15847 19930 2 1028.567559 515.29 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 6 3734.5 - 7.68E+06 - - - 2.0203 - 1.926 0.272 - 393.5 1 2 0 0.0021 8 0 0 0 1.72E+08 1.91E+08 - - - 3.0261 1 230117_WJC_METTL3_WT_vs_EV_F02.19931.19931.3 8.60E-09 20/60 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 90.28 15848 19931 3 1787.006563 596.6753 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3734.6 - 1.46E+06 - - - 1.4175 - 3.811 0.579 - 685.5 1 2 0 0.0025 16 0 0 0 2.28E+08 2.53E+06 - - - 8.4274 1 230117_WJC_METTL3_WT_vs_EV_F02.19932.19932.2 1.53E-06 14/20 R.WGAFAQSILER[166.11].G sp|Q13472|TOP3A_HUMAN 1 1286.6647 0.001 15849 19932 2 1286.663847 644.3396 DNA topoisomerase 3-alpha OS=Homo sapiens OX=9606 GN=TOP3A PE=1 SV=1 6 3734.7 - 985320 - - - -0.656 - 2.804 0.623 - 881.5 1 2 0 -0.0008 11 0 0 0 0.00E+00 1.35E+07 - - - 6.4314 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.19934.19934.2 0.0771 14-Jun R.SLPVFPFR.E "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 961.5385 1.32 15851 19934 2 961.539798 481.7765 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 9.47 3735 - 653920 - - - 1.3104 - 1.213 0.228 - 177.9 1 2 0 0.0013 8 0 0 0 8.79E+06 6.67E+06 - - - 1.307 1 230117_WJC_METTL3_WT_vs_EV_F02.19935.19935.2 0.000761 13/24 R.VETPVLPPVLVPR.H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1414.8548 1.61 15852 19935 2 1414.853223 708.4347 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3735.1 - 592319 - - - -1.1054 - 2.3 0.544 - 402.7 1 2 0 -0.0016 13 0 0 0 1.17E+07 7.27E+06 - - - 5.1962 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.19937.19937.2 0.000163 18-Nov R.SPVTFLSDLR.S sp|A5YKK6|CNOT1_HUMAN 1 1133.6081 1.41 15854 19937 2 1133.605929 567.8113 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 5.55 3735.4 - 524145 - - - -1.8922 - 1.989 0.48 - 371.1 1 2 0 -0.0021 10 0 0 0 9.99E+06 7.10E+06 - - - 4.505 0.999 230117_WJC_METTL3_WT_vs_EV_F02.19938.19938.3 0.0265 Oct-40 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 25.47 15855 19938 3 1276.704643 426.5748 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3735.5 - 510195 - - - 1.5195 - 2.092 0.227 - 205.5 1 2 0 0.0019 11 0 0 0 8.32E+06 3.27E+05 - - - 3.1672 1 230117_WJC_METTL3_WT_vs_EV_F02.19939.19939.2 1.46E-05 13/20 K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 9.09 15856 19939 2 1184.715769 593.3637 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3735.6 - 287746 - - - 2.4445 - 2.669 0.527 - 699.7 1 2 0 0.0029 11 0 0 0 2.16E+09 2.38E+08 - - - 5.5883 1 230117_WJC_METTL3_WT_vs_EV_F02.19942.19942.2 0.000407 13/20 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 82.14 15858 19942 2 1276.704084 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3736 - 4.99E+07 - - - 1.0817 - 2.715 0.424 - 899 1 2 0 0.0014 11 0 0 0 1.22E+09 1.48E+07 - - - 4.8742 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.19944.19944.2 0.000896 18-Sep R.AAFVLPEFAR.K "sp|P19623|SPEE_HUMAN,tr|K7EL89|K7EL89_HUMAN" 2 1119.6077 5.26 15859 19944 2 1119.606598 560.8111 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 6.05 3736.2 - 4.86E+06 - - - -0.9664 - 1.969 0.421 - 211.1 1 2 0 -0.0011 10 0 0 0 3.85E+07 7.32E+06 - - - 4.0413 1 230117_WJC_METTL3_WT_vs_EV_F02.19946.19946.2 0.000214 18-Nov R.QEVVDLLLAR[166.11].G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1164.6742 1.27 15861 19946 2 1164.673888 583.3444 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3736.4 - 3.26E+06 - - - -0.2619 - 2.184 0.474 - 579.9 1 2 0 -0.0003 10 0 0 0 7.72E+07 6.05E+07 - - - 4.7223 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.19949.19949.2 0.0369 20-Aug -.MLLFVEQVASK.G "sp|Q71RC2|LARP4_HUMAN,tr|F8W1Z5|F8W1Z5_HUMAN" 2 1263.6897 0.38 15864 19949 2 1263.690654 632.8521 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 5.75 3736.5 - 2.26E+06 - - - 0.7589 - 1.651 0.366 - 153.7 1 2 0 0.001 11 0 0 0 1.87E+07 4.86E+07 - - - 3.1003 0.8521 230117_WJC_METTL3_WT_vs_EV_F02.19951.19951.2 8.04 14-Jun R.LIFLDSIK.S "sp|Q99996|AKAP9_HUMAN,tr|A0A0A0MRF6|A0A0A0MRF6_HUMAN,tr|A0A7P0TBH8|A0A7P0TBH8_HUMAN,tr|A0A7P0TAX3|A0A7P0TAX3_HUMAN,tr|A0A7P0T9A9|A0A7P0T9A9_HUMAN,tr|A0A7P0T8N5|A0A7P0T8N5_HUMAN,tr|A0A7P0TBI4|A0A7P0TBI4_HUMAN,tr|A0A7P0Z4Q5|A0A7P0Z4Q5_HUMAN,tr|A0A7P0Z4N5|A0A7P0Z4N5_HUMAN,tr|A0A7P0TAD6|A0A7P0TAD6_HUMAN,tr|A0A7P0T939|A0A7P0T939_HUMAN,tr|A0A7P0T928|A0A7P0T928_HUMAN,tr|A0A7P0TAA2|A0A7P0TAA2_HUMAN" 13 947.5692 1.22 15865 19951 2 947.568102 474.7919 A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4 5.84 3736.6 - 1.33E+06 - - - -1.126 - 0.968 0.053 - 81.5 1 2 0 -0.0011 8 0 0 0 5.85E+06 4.78E+06 - - - -0.666 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.19952.19952.2 0.2 14-Jul R.LIFLDSIK[136.11].S "sp|Q99996|AKAP9_HUMAN,tr|A0A0A0MRF6|A0A0A0MRF6_HUMAN,tr|A0A7P0TBH8|A0A7P0TBH8_HUMAN,tr|A0A7P0TAX3|A0A7P0TAX3_HUMAN,tr|A0A7P0T9A9|A0A7P0T9A9_HUMAN,tr|A0A7P0T8N5|A0A7P0T8N5_HUMAN,tr|A0A7P0TBI4|A0A7P0TBI4_HUMAN,tr|A0A7P0Z4Q5|A0A7P0Z4Q5_HUMAN,tr|A0A7P0Z4N5|A0A7P0Z4N5_HUMAN,tr|A0A7P0TAD6|A0A7P0TAD6_HUMAN,tr|A0A7P0T939|A0A7P0T939_HUMAN,tr|A0A7P0T928|A0A7P0T928_HUMAN,tr|A0A7P0TAA2|A0A7P0TAA2_HUMAN" 13 955.5834 1.22 15866 19952 2 955.584135 478.799 A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4 5.84 3736.7 - 1.14E+06 - - - 0.8016 - 1.298 0.225 - 116.6 1 2 0 0.0008 8 0 0 0 5.85E+06 4.78E+06 - - - 1.4892 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.19957.19957.2 1.51E-05 16-Sep K.YDWDLLAAR[166.11].S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1131.5588 1.82 15871 19957 2 1131.559134 566.7867 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3737 - 1.16E+06 - - - 0.2695 - 1.919 0.47 - 323.8 1 2 0 0.0003 9 0 0 0 8.50E+07 4.68E+07 - - - 4.398 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.19961.19961.2 0.00525 18-Oct R.QEVVDLLLAR.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1154.6659 1.11 15873 19961 2 1154.662571 578.3402 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3737.4 - 1.12E+07 - - - -2.903 - 2.243 0.422 - 480.9 1 2 0 -0.0034 10 0 0 0 4.32E+07 3.89E+07 - - - 4.4117 1 230117_WJC_METTL3_WT_vs_EV_F02.19962.19962.2 1.25E-10 15/26 K.FYGPAGPYGIFAGR[166.11].D sp|O15173|PGRC2_HUMAN 1 1481.7331 1.16 15874 19962 2 1481.730654 741.8738 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3737.6 - 1.07E+06 - - - -1.6541 - 2.545 0.671 - 787 1 2 0 -0.0025 14 0 0 0 7.52E+06 6.48E+06 - - - 6.3404 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19964.19964.2 0.0058 22-Nov R.AVLTFALDSVER[166.11].K "sp|Q9NQT4|EXOS5_HUMAN,tr|M0R050|M0R050_HUMAN" 2 1329.7168 0.91 15876 19964 2 1329.719065 665.8657 Exosome complex component RRP46 OS=Homo sapiens OX=9606 GN=EXOSC5 PE=1 SV=1 4.37 3737.7 - 6.26E+06 - - - 1.7139 - 2.143 0.333 - 275.7 1 2 0 0.0023 12 0 0 0 2.15E+07 2.36E+07 - - - 3.5053 0.9933 230117_WJC_METTL3_WT_vs_EV_F02.19968.19968.2 0.65 16-Sep K.DGLLGAELR.L sp|P43026|GDF5_HUMAN 1 942.5134 4.39 15880 19968 2 942.516882 472.264 Growth\differentiation factor 5 OS=Homo sapiens OX=9606 GN=GDF5 PE=1 SV=3 4.37 3738.1 - 2.12E+06 - - - 3.6466 - 1.588 0.187 - 134.8 3 2 0 0.0034 9 0 0 0 9.73E+06 2.22E+06 - - - 1.5459 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19969.19969.2 0.00123 14-Sep R.IWYLLDGK[136.11].M "sp|Q9BYD1|RM13_HUMAN,tr|E5RFI2|E5RFI2_HUMAN" 2 1014.563 0.44 15881 19969 2 1014.563405 508.2888 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 5.83 3738.2 - 1.75E+06 - - - 0.4307 - 1.974 0.401 - 293 1 2 0 0.0004 8 0 0 0 3.18E+06 7.16E+06 - - - 4.0537 0.981 230117_WJC_METTL3_WT_vs_EV_F02.19970.19970.2 2.95 12-Jul K.DIILPFR[166.11].V "sp|Q96CW1|AP2M1_HUMAN,tr|A0A087WY71|A0A087WY71_HUMAN,tr|C9JJ47|C9JJ47_HUMAN,tr|E9PFW3|E9PFW3_HUMAN" 4 882.5203 1.1 15882 19970 2 882.521334 442.2674 AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2 5.84 3738.3 - 1.68E+06 - - - 1.2181 - 1.37 0 - 231.4 1 2 0 0.0011 7 0 0 0 6.32E+06 5.76E+06 - - - 0.0382 0.988 230117_WJC_METTL3_WT_vs_EV_F02.19971.19971.2 0.0313 16-Oct K.YLGLLENLR[166.11].V "sp|O00159|MYO1C_HUMAN,tr|F5H6E2|F5H6E2_HUMAN" 2 1099.6265 10.85 15883 19971 2 1099.629757 550.8205 Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4 6 3738.4 - 1.61E+06 - - - 2.9483 - 1.629 0.04 - 275 1 2 0 0.0032 9 0 0 0 9.04E+07 8.33E+06 - - - 0.7471 0.9848 230117_WJC_METTL3_WT_vs_EV_F02.19973.19973.2 0.203 12-Jul K.DIILPFR.V "sp|Q96CW1|AP2M1_HUMAN,tr|A0A087WY71|A0A087WY71_HUMAN,tr|C9JJ47|C9JJ47_HUMAN,tr|E9PFW3|E9PFW3_HUMAN" 4 872.512 1.02 15885 19973 2 872.512109 437.2633 AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2 5.84 3738.7 - 1.32E+06 - - - 0.1375 - 1.534 0 - 233 1 2 0 0.0001 7 0 0 0 4.50E+06 4.43E+06 - - - 0.3967 1 230117_WJC_METTL3_WT_vs_EV_F02.19975.19975.2 1.19E-05 14/24 R.AIVFVVDSAAFQR.E "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1421.7667 1.53 15887 19975 2 1421.768118 711.8906 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.88 3739 - 1.06E+06 - - - 0.9974 - 2.78 0.459 - 854.6 1 2 0 0.0014 13 0 0 0 5.28E+06 3.44E+06 - - - 5.0549 1 230117_WJC_METTL3_WT_vs_EV_F02.19977.19977.2 7.10E-05 14/24 R.AIVFVVDSAAFQR[166.11].E "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1431.775 1.62 15889 19977 2 1431.772753 716.8948 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.88 3739.2 - 825741 - - - -1.5484 - 2.742 0.489 - 857.2 1 2 0 -0.0022 13 0 0 0 5.28E+06 3.25E+06 - - - 5.2409 1 230117_WJC_METTL3_WT_vs_EV_F02.19980.19980.2 3.77E-10 13/28 R.LYGPSSVSFADDFVR.S "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 1658.794 999 15892 19980 2 1658.796739 830.4043 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.21 3739.6 - 409829 - - - 1.6289 - 2.675 0.61 - 500.7 1 2 0 0.0027 15 0 0 0 2.60E+06 0.00E+00 - - - 5.9647 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.19983.19983.3 0.0331 Aug-32 K.EFIHILYFR.H "sp|Q9NZ32|ARP10_HUMAN,tr|G3V2Q5|G3V2Q5_HUMAN,tr|G3V5Y4|G3V5Y4_HUMAN,tr|F6S9Y6|F6S9Y6_HUMAN,tr|V9GYX7|V9GYX7_HUMAN" 5 1236.6655 2.63 15894 19983 3 1236.667865 413.2291 Actin-related protein 10 OS=Homo sapiens OX=9606 GN=ACTR10 PE=1 SV=1 6.85 3740 - 791997 - - - 1.889 - 1.569 0.303 - 75.7 1 2 0 0.0023 9 0 0 0 4.92E+06 1.87E+06 - - - 3.275 1 230117_WJC_METTL3_WT_vs_EV_F02.19984.19984.2 2.75E-05 16-Oct K.YDWDLLAAR.S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1121.5506 1.82 15895 19984 2 1121.552041 561.7826 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3740 - 5.92E+06 - - - 1.3214 - 1.883 0.569 - 416.5 1 2 0 0.0015 9 0 0 0 8.50E+07 4.68E+07 - - - 5.0741 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.19986.19986.3 4.71E-05 15/40 K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 8.4 15897 19986 3 1184.713577 395.9116 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3740.2 - 3.28E+06 - - - 0.5942 - 2.821 0.427 - 341.4 1 2 0 0.0007 11 0 0 0 5.32E+07 6.33E+06 - - - 6.2466 1 230117_WJC_METTL3_WT_vs_EV_F02.19989.19989.2 2.39E-05 13/20 K.FDGILGMAYPR.L "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1238.6118 15.45 15900 19989 2 1238.61167 620.3132 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.84 3740.6 - 1.24E+06 - - - -0.088 - 2.412 0.456 - 784.2 1 2 0 -0.0001 11 0 0 0 2.33E+07 1.51E+06 - - - 4.7908 0.9375 230117_WJC_METTL3_WT_vs_EV_F02.19990.19990.2 3.17E-05 20-Oct K.FEQLVSIGSSY.N sp|Q9NXV2|KCTD5_HUMAN 1 1228.5976 - 15901 19990 2 1228.596238 615.3061 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4 3740.7 - 1.22E+06 - - - -1.0833 - 1.73 0.494 - 352.8 1 1 0 -0.0013 11 0 0 0 - - - - - 4.1721 0.9938 230117_WJC_METTL3_WT_vs_EV_F02.19991.19991.3 0.000842 Dec-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 89.94 15902 19991 3 1803.023749 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3740.8 - 788956 - - - -4.8147 - 2.593 0.318 - 193.2 1 2 0 -0.0087 16 0 0 0 2.27E+08 2.53E+06 - - - 4.5278 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.19995.19995.3 0.0259 Nov-40 K.TAVETAVLLLR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1194.7211 8.4 15906 19995 3 1194.72173 399.2477 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3741.4 - 499272 - - - 0.4913 - 2.065 0.3 - 124.1 1 2 0 0.0006 11 0 0 0 5.32E+07 6.33E+06 - - - 3.9445 0.9933 230117_WJC_METTL3_WT_vs_EV_F02.19997.19997.3 0.179 Jul-36 K.LFDIRPIWSR.N "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U4|Q5T7U4_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1301.7244 1.99 15908 19997 3 1301.726127 434.9154 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 9.6 3741.6 - 480518 - - - 1.2952 - 1.617 0.177 - 55.5 2 2 0 0.0017 10 0 0 0 3.84E+06 1.93E+06 - - - 1.7771 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.20000.20000.2 0.434 20-Oct K.TYSYLTPDLWK.E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1385.6867 0.19 15911 20000 2 1385.687987 693.8506 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.5 3742 - 398629 - - - 0.9158 - 1.464 0.251 - 239.1 1 2 0 0.0013 11 0 0 0 2.10E+06 1.10E+07 - - - 1.9256 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20001.20001.2 0.00377 20-Nov R.IAIQGIITAIK[136.11].Y sp|Q6NSI4|RADX_HUMAN 1 1147.742 3.69 15912 20001 2 1147.743695 574.8783 RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2 8.75 3742.1 - 372731 - - - 1.4812 - 2.129 0.286 - 194.1 1 2 0 0.0017 11 0 0 0 7.02E+06 1.90E+06 - - - 3.1971 0.8953 230117_WJC_METTL3_WT_vs_EV_F02.20003.20003.2 4.65 16-May K.EFIHILYFR[166.11].H "sp|Q9NZ32|ARP10_HUMAN,tr|G3V2Q5|G3V2Q5_HUMAN,tr|G3V5Y4|G3V5Y4_HUMAN,tr|F6S9Y6|F6S9Y6_HUMAN,tr|V9GYX7|V9GYX7_HUMAN" 5 1246.6738 -1 15913 20003 2 1246.676223 624.3442 Actin-related protein 10 OS=Homo sapiens OX=9606 GN=ACTR10 PE=1 SV=1 6.85 3742.4 - 280464 - - - 1.9444 - 0.883 0.039 - 95 1 2 0 0.0024 9 0 0 0 0.00E+00 0.00E+00 - - - -1.0317 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20005.20005.2 0.00181 18-Sep R.DAVLLVFANK.Q "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 5 1088.623 1.94 15915 20005 2 1088.623505 545.3188 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 5.84 3742.5 - 3.29E+06 - - - 0.4676 - 2.011 0.405 - 427.9 1 2 0 0.0005 10 0 0 0 1.85E+08 9.54E+07 - - - 3.9823 1 230117_WJC_METTL3_WT_vs_EV_F02.20006.20006.2 3.95E-07 14/26 K.FYGPAGPYGIFAGR.D sp|O15173|PGRC2_HUMAN 1 1471.7248 1.38 15916 20006 2 1471.725397 736.8697 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3742.6 - 1.82E+06 - - - 0.3819 - 2.35 0.539 - 778.8 1 2 0 0.0006 14 0 0 0 3.32E+07 2.41E+07 - - - 5.166 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20008.20008.2 0.000107 18-Nov R.LLVVYPWTQR.F "sp|P69892|HBG2_HUMAN,sp|P69891|HBG1_HUMAN,sp|P02042|HBD_HUMAN,sp|P02100|HBE_HUMAN,sp|P68871|HBB_HUMAN,tr|A0A2R8Y7R2|A0A2R8Y7R2_HUMAN,tr|E9PEW8|E9PEW8_HUMAN,tr|E9PFT6|E9PFT6_HUMAN,tr|F8W6P5|F8W6P5_HUMAN,tr|A0A2R8Y7X9|A0A2R8Y7X9_HUMAN" 10 1273.7183 999 15918 20008 2 1273.720117 637.8664 Hemoglobin subunit gamma-2 OS=Homo sapiens OX=9606 GN=HBG2 PE=1 SV=2 8.75 3742.7 - 1.44E+06 - - - 1.432 - 2.073 0.38 - 560.7 1 2 0 0.0018 10 0 0 0 2.83E+07 0.00E+00 - - - 3.882 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20015.20015.2 0.00114 20-Dec R.IAIQGIITAIK.Y sp|Q6NSI4|RADX_HUMAN 1 1139.7278 3.69 15923 20015 2 1139.728191 570.8712 RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2 8.75 3743.4 - 1.32E+06 - - - 0.3475 - 2.123 0.382 - 300.5 1 2 0 0.0004 11 0 0 0 7.02E+06 1.90E+06 - - - 3.8989 0.9948 230117_WJC_METTL3_WT_vs_EV_F02.20016.20016.2 0.648 14-Aug R.SLLSILQR.S "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 928.5706 2.03 15924 20016 2 928.570781 465.2926 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 9.47 3743.5 - 872405 - - - 0.2315 - 1.503 0.119 - 235.6 1 2 0 0.0002 8 0 0 0 1.26E+07 6.23E+06 - - - 1.1488 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20017.20017.3 4.86E-05 Dec-44 R.ALAVHLLDLGLR.R sp|Q86Y56|DAAF5_HUMAN 1 1289.782 0.41 15925 20017 3 1289.782131 430.9346 Dynein axonemal assembly factor 5 OS=Homo sapiens OX=9606 GN=DNAAF5 PE=1 SV=4 6.79 3743.6 - 698021 - - - 0.1357 - 2.081 0.3 - 218.6 1 2 0 0.0002 12 0 0 0 2.62E+06 6.35E+06 - - - 3.916 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.20018.20018.2 0.646 12-Aug R.VTLLLFK.D "sp|Q9Y3C4|TPRKB_HUMAN,sp|Q86YN1|DOPP1_HUMAN,tr|H7C1Z8|H7C1Z8_HUMAN,tr|H7BXT6|H7BXT6_HUMAN" 4 832.5422 1.68 15926 20018 2 832.543635 417.2784 EKC\KEOPS complex subunit TPRKB OS=Homo sapiens OX=9606 GN=TPRKB PE=1 SV=1 8.72 3743.8 - 500590 - - - 1.6924 - 1.688 0.121 - 224 1 2 0 0.0014 7 0 0 0 3.26E+06 1.94E+06 - - - 1.5931 0.9889 230117_WJC_METTL3_WT_vs_EV_F02.20027.20027.2 0.000331 14-Sep R.IWYLLDGK.M "sp|Q9BYD1|RM13_HUMAN,tr|E5RFI2|E5RFI2_HUMAN" 2 1006.5488 0.69 15933 20027 2 1006.545531 504.2817 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 5.83 3744.7 - 731130 - - - -3.2159 - 1.757 0.221 - 249.1 1 2 0 -0.0032 8 0 0 0 5.63E+06 8.16E+06 - - - 2.3721 1 230117_WJC_METTL3_WT_vs_EV_F02.20032.20032.2 0.00397 16/28 R.LPLPSPALEYTLGSR.L sp|Q8IU81|I2BP1_HUMAN 1 1612.8825 2.86 15936 20032 2 1612.886541 807.4485 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3745.3 - 456801 - - - 2.5315 - 2.686 0.463 - 634.8 1 2 0 0.0041 15 0 0 0 6.48E+07 2.27E+07 - - - 4.8886 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20033.20033.2 0.00267 13/20 R.TLVLLDNLNVR[166.11].E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1278.7535 1.3 15937 20033 2 1278.755316 640.384 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3745.4 - 758235 - - - 1.4154 - 2.503 0.395 - 695 1 2 0 0.0018 11 0 0 0 5.31E+07 4.08E+07 - - - 4.4399 1 230117_WJC_METTL3_WT_vs_EV_F02.20035.20035.2 1.72E-08 13/22 K.LYDNLLEQNLIR.V sp|O00231|PSD11_HUMAN 1 1502.8093 1.8 15939 20035 2 1502.810445 752.4119 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3745.7 - 306325 - - - 0.7666 - 2.906 0.56 - 761.4 1 2 0 0.0012 12 0 0 0 4.26E+07 2.36E+07 - - - 5.9837 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20036.20036.2 0.0056 18-Jul R.LWGDIYFNPK[136.11].T sp|Q15029|U5S1_HUMAN 1 1259.643 1.45 15940 20036 2 1259.644075 630.8288 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.83 3745.8 - 300153 - - - 0.8463 - 1.639 0.336 - 126.1 1 2 0 0.0011 10 0 0 0 8.30E+06 5.71E+06 - - - 2.9015 0.9931 230117_WJC_METTL3_WT_vs_EV_F02.20038.20038.2 0.0517 20-Aug R.YLLQPLGDFSR.A "sp|Q7Z3U7|MON2_HUMAN,tr|A0A286YFF8|A0A286YFF8_HUMAN" 2 1307.6874 -1 15942 20038 2 1307.691127 654.851 Protein MON2 homolog OS=Homo sapiens OX=9606 GN=MON2 PE=1 SV=3 5.84 3746 - 130157 - - - 2.86 - 1.516 0.13 - 213.6 1 2 0 0.0037 11 0 0 0 0.00E+00 0.00E+00 - - - 1.1256 0.9949 230117_WJC_METTL3_WT_vs_EV_F02.20041.20041.2 0.582 16-Aug R.LVLDPYLLK[136.11].Y "sp|Q9Y2R5|RT17_HUMAN,tr|I3L0E3|I3L0E3_HUMAN,tr|E9PE17|E9PE17_HUMAN" 3 1080.6674 0.95 15943 20041 2 1080.667917 541.341 "28S ribosomal protein S17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS17 PE=1 SV=1" 5.83 3746.5 - 1.16E+06 - - - 0.4479 - 1.359 0.159 - 125 1 2 0 0.0005 9 0 0 0 3.48E+07 3.69E+07 - - - 1.1027 1 230117_WJC_METTL3_WT_vs_EV_F02.20043.20043.3 4.53E-15 28/76 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 3.38 15945 20043 3 2197.090056 733.3694 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3746.8 - 965669 - - - 1.7296 - 5.271 0.635 - 1077.2 1 2 0 0.0038 20 0 0 0 9.00E+06 2.66E+06 - - - 9.6512 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.20044.20044.2 0.0017 16-Oct K.SLTYLSILR.N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 3 1064.623 1.37 15946 20044 2 1064.626712 533.3188 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 8.46 3746.9 - 894829 - - - 3.4904 - 1.861 0.434 - 336.7 1 2 0 0.0037 9 0 0 0 1.31E+07 9.62E+06 - - - 4.0423 0.999 230117_WJC_METTL3_WT_vs_EV_F02.20045.20045.2 0.000282 16-Oct K.SLTYLSILR[166.11].N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 3 1074.6313 1.42 15947 20045 2 1074.630202 538.3229 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 8.46 3747 - 1.39E+06 - - - -0.9901 - 1.835 0.393 - 313.4 1 2 0 -0.0011 9 0 0 0 1.31E+07 9.27E+06 - - - 3.6996 1 230117_WJC_METTL3_WT_vs_EV_F02.20046.20046.2 2.52E-07 13/22 K.LYDNLLEQNLIR[166.11].V sp|O00231|PSD11_HUMAN 1 1512.8176 1.8 15948 20046 2 1512.820814 757.4161 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3747.1 - 572810 - - - 2.149 - 2.939 0.544 - 622.6 1 2 0 0.0033 12 0 0 0 4.26E+07 2.36E+07 - - - 5.8945 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.20047.20047.2 0.364 16-Sep R.NLLGLALGR[166.11].L sp|Q8N5L8|RP25L_HUMAN 1 935.5792 1.11 15949 20047 2 935.581803 468.7969 Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1 9.75 3747.3 - 535196 - - - 2.8132 - 1.602 0.225 - 285.7 1 2 0 0.0026 9 0 0 0 4.98E+07 4.48E+07 - - - 2.0654 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.20048.20048.2 0.000942 18-Oct R.LWGDIYFNPK.T sp|Q15029|U5S1_HUMAN 1 1251.6288 1.42 15950 20048 2 1251.633643 626.8217 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.83 3747.4 - 526527 - - - 3.8622 - 2.168 0.429 - 289.9 1 2 0 0.0048 10 0 0 0 8.30E+06 5.82E+06 - - - 4.368 1 230117_WJC_METTL3_WT_vs_EV_F02.20049.20049.2 8.42E-05 18-Nov K.GIGFLTSGWR[166.11].F sp|Q8IXM3|RM41_HUMAN 1 1102.5799 1.18 15951 20049 2 1102.58492 552.2972 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 9.75 3747.5 - 669188 - - - 4.5539 - 2.103 0.476 - 455.3 1 2 0 0.005 10 0 0 0 3.41E+07 2.90E+07 - - - 4.6301 0.9948 230117_WJC_METTL3_WT_vs_EV_F02.20051.20051.2 6.56E-05 14/28 R.LPLPSPALEYTLGSR[166.11].L sp|Q8IU81|I2BP1_HUMAN 1 1622.8907 2.86 15953 20051 2 1622.884286 812.4526 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3747.8 - 1.67E+06 - - - -3.9695 - 1.786 0.498 - 272.2 1 2 0 -0.0064 15 0 0 0 6.48E+07 2.27E+07 - - - 4.1431 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20053.20053.2 0.012 13/24 R.ATVGILITTIASK.G "sp|Q92973|TNPO1_HUMAN,tr|A0A7P0T9C0|A0A7P0T9C0_HUMAN,tr|A0A7P0TBF0|A0A7P0TBF0_HUMAN,tr|A0A7P0T944|A0A7P0T944_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 5 1286.781 2.01 15955 20053 2 1286.783836 644.3978 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 8.8 3748.1 - 243385 - - - 2.2405 - 2.268 0.343 - 520.6 1 2 0 0.0029 13 0 0 0 4.15E+06 2.06E+06 - - - 3.6752 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.20054.20054.3 0.026 Sep-40 R.LIHPVQFVFLR.K "sp|Q2TAA5|ALG11_HUMAN,tr|A0A7P0T8Y4|A0A7P0T8Y4_HUMAN,tr|A0A3B3IS90|A0A3B3IS90_HUMAN" 3 1367.8078 1.08 15956 20054 3 1367.812324 456.9432 "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Homo sapiens OX=9606 GN=ALG11 PE=1 SV=2" 9.76 3748.2 - 178535 - - - 3.3243 - 1.822 0.315 - 125.6 1 2 0 0.0045 11 0 0 0 1.69E+06 1.56E+06 - - - 3.755 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20058.20058.2 0.000735 16-Sep R.GFFGFPGPR.S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 980.4868 1.68 15960 20058 2 980.488094 491.2507 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3748.7 - 125841 - - - 1.282 - 1.649 0.392 - 242.1 1 2 0 0.0013 9 0 0 0 1.84E+06 1.10E+06 - - - 3.3829 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20062.20062.2 0.000295 16-Aug K.FFPLIEVNK.V "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1105.6172 0.85 15963 20062 2 1105.619995 553.8159 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6 3749.2 - 4.76E+06 - - - 2.5443 - 1.614 0.427 - 173 1 2 0 0.0028 9 0 0 0 8.08E+07 9.51E+07 - - - 3.5789 0.9499 230117_WJC_METTL3_WT_vs_EV_F02.20064.20064.2 1.85E-05 20-Nov R.PMEVFMC[160.03]SVLK[136.11].R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1347.648 1.16 15965 20064 2 1347.651863 674.8313 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3749.4 - 1.35E+06 - - - 2.839 - 1.972 0.365 - 415.6 1 1 0 0.0038 11 0 0 0 2.95E+07 2.54E+07 - - - 3.5727 1 230117_WJC_METTL3_WT_vs_EV_F02.20065.20065.2 9.68E-05 18/30 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 8.32 15966 20065 2 1549.886052 775.9487 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3749.5 - 1.14E+06 - - - 2.1034 - 2.968 0.493 - 1019.4 1 2 0 0.0033 16 0 0 0 7.64E+08 9.18E+07 - - - 5.3559 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20067.20067.2 0.00463 20-Sep R.IFGGLDMLAEK[136.11].L sp|Q92688|AN32B_HUMAN 1 1200.6304 0.95 15968 20067 2 1200.630886 601.3225 Acidic leucine-rich nuclear phosphoprotein 32 family member B OS=Homo sapiens OX=9606 GN=ANP32B PE=1 SV=1 4.37 3749.7 - 940219 - - - 0.4081 - 1.509 0.406 - 125.3 1 2 0 0.0005 11 0 0 0 3.81E+06 4.00E+06 - - - 3.1526 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.20072.20072.2 0.00306 20-Sep R.VFSWGFGGYGR.L sp|Q9P258|RCC2_HUMAN 1 1231.5774 2.1 15973 20072 2 1231.576404 616.796 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 8.72 3750.2 - 404285 - - - -0.8436 - 1.896 0.4 - 203.6 1 2 0 -0.001 11 0 0 0 1.12E+07 5.31E+06 - - - 3.7257 1 230117_WJC_METTL3_WT_vs_EV_F02.20075.20075.2 0.00256 14/26 R.LEALLEAADPEVLR.R tr|D6RHC4|D6RHC4_HUMAN 1 1537.8352 2.07 15976 20075 2 1537.837359 769.9249 Ankyrin repeat and KH domain-containing protein 1 (Fragment) OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4 3750.6 - 321665 - - - 1.4208 - 2.895 0.488 - 626.5 1 2 0 0.0022 14 0 0 0 3.28E+06 1.59E+06 - - - 5.3122 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20078.20078.2 0.000102 24-Aug R.LYSTSASPLVLLR.T "sp|Q9Y2Z9|COQ6_HUMAN,tr|A0A0D9SFJ1|A0A0D9SFJ1_HUMAN" 2 1418.8133 -1 15979 20078 2 1418.815771 710.4139 "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial OS=Homo sapiens OX=9606 GN=COQ6 PE=1 SV=2" 8.75 3751 - 198485 - - - 1.7303 - 1.896 0.486 - 83.2 1 2 0 0.0025 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2718 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20081.20081.2 0.00113 20-Nov K.TVLELQYVLDK.L "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1319.7337 1.16 15981 20081 2 1319.734672 660.8741 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.37 3751.4 - 4.74E+07 - - - 0.76 - 2.252 0.433 - 267.1 1 2 0 0.001 11 0 0 0 2.10E+08 1.81E+08 - - - 4.435 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20084.20084.2 0.0501 18-Oct K.GIGFLTSGWR.F sp|Q8IXM3|RM41_HUMAN 1 1092.5716 1.18 15984 20084 2 1092.574694 547.2931 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 9.75 3751.5 - 7.27E+06 - - - 2.8053 - 1.882 0.447 - 321 1 2 0 0.0031 10 0 0 0 3.41E+07 2.90E+07 - - - 4.1066 1 230117_WJC_METTL3_WT_vs_EV_F02.20086.20086.2 8.30E-09 13/20 R.PMEVFMC[160.03]SVLK.R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1339.6338 1.16 15986 20086 2 1339.63622 670.8242 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3751.6 - 3.92E+06 - - - 1.7788 - 2.71 0.621 - 628.4 1 1 0 0.0024 11 0 0 0 2.94E+07 2.54E+07 - - - 6.3239 1 230117_WJC_METTL3_WT_vs_EV_F02.20087.20087.2 0.0003 20/30 R.ALIAGGGAPEIELALR[166.11].L sp|P50991|TCPD_HUMAN 1 1559.8911 8.25 15987 20087 2 1559.893252 780.9528 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3751.7 - 3.17E+06 - - - 1.4039 - 2.977 0.445 - 1617.2 1 2 0 0.0022 16 0 0 0 7.65E+08 9.27E+07 - - - 5.0091 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.20090.20090.2 0.0826 16-Aug R.GSLITSLLR.S sp|Q53FA7|QORX_HUMAN 1 958.5811 1.05 15990 20090 2 958.582827 480.2978 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3752.1 - 1.27E+06 - - - 1.7693 - 1.874 0.237 - 178.3 1 2 0 0.0017 9 0 0 0 5.60E+06 5.34E+06 - - - 2.608 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20091.20091.3 0.00667 Dec-44 K.LYDNLLEQNLIR.V sp|O00231|PSD11_HUMAN 1 1502.8093 1.17 15991 20091 3 1502.812841 501.9437 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3752.2 - 1.21E+06 - - - 2.3609 - 2.327 0.255 - 332.6 1 2 0 0.0035 12 0 0 0 2.13E+06 1.83E+06 - - - 3.7231 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20093.20093.3 0.000473 Oct-40 R.TLVLLDNLNVR.E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1268.7452 1.78 15993 20093 3 1268.74692 423.9224 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3752.5 - 664132 - - - 1.3273 - 1.919 0.302 - 187.4 1 2 0 0.0017 11 0 0 0 1.21E+06 6.80E+05 - - - 3.7582 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20094.20094.2 0.0018 26-Nov K.IPPPVIMVQNVSFK.Y sp|Q9UG63|ABCF2_HUMAN 1 1567.8796 2.75 15994 20094 2 1567.882104 784.9471 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.75 3752.6 - 617776 - - - 1.5837 - 2.098 0.421 - 357.2 1 2 0 0.0025 14 0 0 0 7.63E+06 2.78E+06 - - - 4.0092 0.9928 230117_WJC_METTL3_WT_vs_EV_F02.20099.20099.3 0.0183 Jun-40 R.TLVLLDNLNVR[166.11].E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1278.7535 -1 15999 20099 3 1278.755404 427.2584 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3753.3 - 292863 - - - 1.4843 - 1.596 0.18 - 65.8 2 2 0 0.0019 11 0 0 0 0.00E+00 0.00E+00 - - - 1.7351 0.9799 230117_WJC_METTL3_WT_vs_EV_F02.20102.20102.2 0.837 14-May K.IPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1059.5502 2.57 16001 20102 2 1059.555036 530.7824 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3753.6 - 858534 - - - 4.5972 - 1.313 0.178 - 73.8 1 2 0 0.0049 8 0 0 0 5.08E+06 1.97E+06 - - - 1.1755 1 230117_WJC_METTL3_WT_vs_EV_F02.20104.20104.3 2.96E-07 14/60 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 7.61 16003 20104 3 1549.883907 517.6349 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3753.7 - 3.29E+06 - - - 0.7194 - 2.631 0.596 - 371.8 1 2 0 0.0011 16 0 0 0 3.28E+07 4.31E+06 - - - 7.6666 0.9892 230117_WJC_METTL3_WT_vs_EV_F02.20105.20105.2 2.51 14-Jun R.YGLEC[160.03]LFR[166.11].Y "sp|Q6PKG0|LARP1_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN" 3 1066.5145 0.92 16004 20105 2 1066.515084 534.2645 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 5.99 3753.8 - 2.06E+06 - - - 0.527 - 1.132 0.15 - 103.6 1 2 0 0.0006 8 0 0 0 8.82E+06 9.58E+06 - - - 0.5227 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20106.20106.2 0.0125 14-Sep R.YGLEC[160.03]LFR.Y "sp|Q6PKG0|LARP1_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN" 3 1056.5063 0.73 16005 20106 2 1056.507064 529.2604 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 5.99 3753.8 - 1.74E+06 - - - 0.7686 - 1.868 0.402 - 309.7 1 2 0 0.0008 8 0 0 0 8.79E+06 1.21E+07 - - - 3.8945 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20109.20109.2 0.0505 16-Oct R.GSLITSLLR[166.11].S sp|Q53FA7|QORX_HUMAN 1 968.5894 1.05 16008 20109 2 968.590188 485.302 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3754.1 - 1.11E+06 - - - 0.8125 - 2.025 0.244 - 279.9 1 2 0 0.0008 9 0 0 0 5.60E+06 5.34E+06 - - - 2.8842 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20111.20111.2 0.00133 20-Oct R.VFSWGFGGYGR[166.11].L sp|Q9P258|RCC2_HUMAN 1 1241.5857 2.08 16010 20111 2 1241.5853 621.8001 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 8.72 3754.3 - 808971 - - - -0.3326 - 1.691 0.44 - 76.3 1 2 0 -0.0004 11 0 0 0 1.11E+07 5.31E+06 - - - 3.7118 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20112.20112.2 0.000125 16-Aug R.GFFGFPGPR[166.11].S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 990.4951 2.02 16011 20112 2 990.495277 496.2548 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3754.3 - 776529 - - - 0.1716 - 1.496 0.423 - 156.5 1 2 0 0.0002 9 0 0 0 3.43E+07 1.70E+07 - - - 3.3305 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.20113.20113.2 0.00115 18-Aug R.VFYYLVQDLK.C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1286.6911 0.93 16012 20113 2 1286.696658 644.3528 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3754.4 - 744706 - - - 4.339 - 1.773 0.429 - 209.6 1 2 0 0.0056 10 0 0 0 7.72E+07 8.27E+07 - - - 3.8063 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20118.20118.2 0.000546 18-Jul K.LFQLQTLGLK.G "sp|Q9ULM6|CNOT6_HUMAN,sp|Q96LI5|CNO6L_HUMAN,tr|D6RGK9|D6RGK9_HUMAN,tr|H0Y9C1|H0Y9C1_HUMAN,tr|H0Y9Z5|H0Y9Z5_HUMAN" 5 1159.6965 1.21 16016 20118 2 1159.695816 580.8555 CCR4-NOT transcription complex subunit 6 OS=Homo sapiens OX=9606 GN=CNOT6 PE=1 SV=2 8.75 3754.8 - 569341 - - - -0.5855 - 1.847 0.423 - 113.4 1 2 0 -0.0007 10 0 0 0 5.00E+06 4.13E+06 - - - 3.8777 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.20119.20119.2 0.213 12-Jul R.WIVNLIR[166.11].N "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 15 922.5628 0.89 16017 20119 2 922.562982 462.2887 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 9.75 3754.8 - 5.25E+06 - - - 0.2059 - 1.425 0.276 - 277.8 1 2 0 0.0002 7 0 0 0 3.63E+07 4.09E+07 - - - 2.2017 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.20122.20122.2 0.000355 18-Oct R.YVEFNLLYDR.G "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1330.6558 1.51 16020 20122 2 1330.662884 666.3352 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.37 3755 - 5.69E+06 - - - 5.3598 - 1.951 0.465 - 286.8 1 2 0 0.0071 10 0 0 0 2.35E+07 1.56E+07 - - - 4.3388 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.20124.20124.2 0.000721 18-Oct K.YFSSMAEFLK.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1221.574 1.21 16022 20124 2 1221.572112 611.7943 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 3755.1 - 1.08E+06 - - - -1.5431 - 1.662 0.445 - 225.5 1 2 0 -0.0019 10 0 0 0 5.44E+07 4.50E+07 - - - 3.7452 0.9163 230117_WJC_METTL3_WT_vs_EV_F02.20125.20125.3 0.936 Dec-60 R.ALIAGGGAPEIELALR[166.11].L sp|P50991|TCPD_HUMAN 1 1559.8911 7.61 16023 20125 3 1559.891015 520.971 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3755.1 - 854739 - - - -0.0301 - 1.576 0.058 - 169.9 1 2 0 0 16 0 0 0 3.28E+07 4.31E+06 - - - 0.3538 1 230117_WJC_METTL3_WT_vs_EV_F02.20128.20128.2 1.48E-07 18-Nov R.VFYYLVQDLK[136.11].C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1294.7053 0.94 16024 20128 2 1294.706605 648.3599 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3755.5 - 5.35E+06 - - - 1.0273 - 2.397 0.545 - 482 1 2 0 0.0013 10 0 0 0 7.74E+07 8.27E+07 - - - 5.5062 1 230117_WJC_METTL3_WT_vs_EV_F02.20133.20133.3 2.67E-05 16/52 K.IPPPVIMVQNVSFK.Y sp|Q9UG63|ABCF2_HUMAN 1 1567.8796 4.12 16029 20133 3 1567.879942 523.6338 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.75 3756 - 1.00E+06 - - - 0.2047 - 3.068 0.486 - 554 1 2 0 0.0003 14 0 0 0 4.13E+06 1.00E+06 - - - 6.9375 0.9925 230117_WJC_METTL3_WT_vs_EV_F02.20139.20139.2 2.56 14-Sep R.LLLEDLVK.K "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 941.5797 1.73 16035 20139 2 941.580054 471.7971 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 4.37 3756.8 - 509920 - - - 0.3399 - 1.35 0.12 - 194.3 1 2 0 0.0003 8 0 0 0 3.11E+06 1.80E+06 - - - 0.8323 0.9903 230117_WJC_METTL3_WT_vs_EV_F02.20152.20152.2 0.0267 20-Jul R.YLLLLAAGDPR.E "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1200.6867 3.02 16047 20152 2 1200.682485 601.3506 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.84 3758.1 - 721955 - - - -3.4763 - 1.644 0.313 - 141.5 1 2 0 -0.0042 11 0 0 0 6.04E+06 2.00E+06 - - - 2.6964 0.9852 230117_WJC_METTL3_WT_vs_EV_F02.20155.20155.2 1.62 14-Aug R.LLLEDLVK[136.11].K "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 949.5939 1.73 16050 20155 2 949.593656 475.8042 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 4.37 3758.5 - 348707 - - - -0.2928 - 1.075 0.179 - 132.8 1 2 0 -0.0003 8 0 0 0 3.11E+06 1.80E+06 - - - 0.5811 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20159.20159.2 0.000274 18-Nov R.QEVVELLLAR.G "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1168.6816 0.95 16052 20159 2 1168.681801 585.3481 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.53 3759 - 2.41E+06 - - - 0.1951 - 2.383 0.412 - 481.7 1 2 0 0.0002 10 0 0 0 7.86E+06 8.25E+06 - - - 4.5078 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20160.20160.2 0.00231 14-Sep R.WLLSDYVK.V "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN,tr|C9JZH6|C9JZH6_HUMAN" 3 1022.5437 1.99 16053 20160 2 1022.545603 512.2791 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.83 3759.1 - 1.71E+06 - - - 1.8777 - 1.727 0.296 - 400.8 1 2 0 0.0019 8 0 0 0 7.22E+06 3.64E+06 - - - 2.8745 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20161.20161.3 0.0189 16/40 R.AALLELWELR[166.11]R[166.11].Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1388.8043 0.61 16054 20161 3 1388.805425 463.942 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.19 3759.3 - 1.60E+06 - - - 0.8028 - 2.634 0.225 - 608.6 1 2 0 0.0011 11 0 0 0 2.75E+06 4.50E+06 - - - 3.7996 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20163.20163.2 0.00636 16-Sep R.LTSFITVFK.Y "sp|Q13617|CUL2_HUMAN,tr|Q5T2B5|Q5T2B5_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 3 1054.6063 3.2 16056 20163 2 1054.608751 528.3104 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 8.75 3759.5 - 1.24E+06 - - - 2.3402 - 2.058 0.361 - 243.3 1 2 0 0.0025 9 0 0 0 9.34E+06 2.92E+06 - - - 3.7946 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.20169.20169.2 0.00279 12-Aug K.LFFLQVK[136.11].E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 901.5517 0.9 16062 20169 2 901.553441 451.7831 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3760.3 - 829144 - - - 1.9588 - 1.666 0.238 - 220.1 1 2 0 0.0018 7 0 0 0 5.50E+06 6.09E+06 - - - 2.4156 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.20172.20172.2 0.219 12-Jun K.LFFLQVK.E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 893.5375 0.9 16065 20172 2 893.538276 447.776 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3760.7 - 575352 - - - 0.8964 - 1.353 0.155 - 108.8 1 2 0 0.0008 7 0 0 0 5.50E+06 6.09E+06 - - - 1.1435 1 230117_WJC_METTL3_WT_vs_EV_F02.20173.20173.2 3.79E-05 20-Sep K.LLVYEALEYAK.R "sp|Q96DB5|RMD1_HUMAN,tr|H0YB83|H0YB83_HUMAN,tr|E5RH53|E5RH53_HUMAN,tr|H0YB03|H0YB03_HUMAN" 4 1310.7122 0.06 16066 20173 2 1310.712267 656.3634 Regulator of microtubule dynamics protein 1 OS=Homo sapiens OX=9606 GN=RMDN1 PE=1 SV=1 4.53 3760.8 - 566712 - - - 0.0473 - 1.947 0.526 - 247.3 1 2 0 0.0001 11 0 0 0 2.26E+06 3.52E+07 - - - 4.7285 1 230117_WJC_METTL3_WT_vs_EV_F02.20177.20177.2 0.00161 22-Dec Y.VLNPLAPEFIPR.A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1364.7816 32.47 16070 20177 2 1364.786258 683.3981 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.97 3761.4 - 413340 - - - 3.3969 - 2.392 0.451 - 469.9 1 1 0 0.0046 12 0 0 0 2.89E+06 8.91E+04 - - - 4.6654 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20180.20180.2 0.00216 14-Aug K.AIFLFVDK[136.11].T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 959.5572 1.41 16072 20180 2 959.558605 480.7859 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3761.6 - 1.65E+06 - - - 1.5122 - 1.514 0.341 - 238.2 1 2 0 0.0014 8 0 0 0 9.19E+06 6.51E+06 - - - 2.8101 0.9903 230117_WJC_METTL3_WT_vs_EV_F02.20181.20181.2 1.22 16-Jun K.LEATINELV.- sp|P10599|THIO_HUMAN 1 1000.5441 - 16073 20181 2 1000.54429 501.2793 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 3.79 3761.7 - 4.48E+06 - - - 0.2129 - 1.228 0.143 - 73.1 1 2 0 0.0002 9 0 0 0 - - - - - 0.6913 0.9664 230117_WJC_METTL3_WT_vs_EV_F02.20182.20182.2 1.13 12-Aug R.IIWELIK.E "sp|O75874|IDHC_HUMAN,tr|C9JLU6|C9JLU6_HUMAN,tr|C9J4N6|C9J4N6_HUMAN,tr|C9JJE5|C9JJE5_HUMAN" 4 913.5637 8.66 16074 20182 2 913.563175 457.7891 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 6 3761.7 - 3.45E+06 - - - -0.5637 - 1.274 0.043 - 156.8 1 2 0 -0.0005 7 0 0 0 2.36E+07 2.73E+06 - - - 0.1257 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20183.20183.2 0.00363 22-Dec K.LGAIFLEGVTVK.G sp|O60942|MCE1_HUMAN 1 1245.7333 47.63 16075 20183 2 1245.7379 623.8739 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 6 3761.8 - 2.77E+06 - - - 3.7127 - 2.342 0.436 - 400.9 1 2 0 0.0046 12 0 0 0 1.09E+07 2.29E+05 - - - 4.499 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20184.20184.2 0.00595 18-Nov R.DLASVQALLR.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1084.6241 0.67 16076 20184 2 1084.62524 543.3193 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3761.8 - 2.70E+06 - - - 1.0898 - 2.287 0.319 - 438.9 1 2 0 0.0012 10 0 0 0 9.63E+06 1.43E+07 - - - 3.7058 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.20185.20185.2 0.0047 14-Aug K.AIFLFVDK.T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 951.543 1.14 16077 20185 2 951.543058 476.7788 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3761.9 - 1.98E+06 - - - 0.1093 - 1.493 0.357 - 233.2 1 2 0 0.0001 8 0 0 0 5.11E+06 4.49E+06 - - - 2.8865 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20188.20188.2 0.000277 20-Oct R.AFITNIPFDVK[136.11].W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1271.7005 2.69 16080 20188 2 1271.702233 636.8575 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3762 - 1.17E+06 - - - 1.3439 - 1.953 0.474 - 334 1 2 0 0.0017 11 0 0 0 3.39E+08 1.26E+08 - - - 4.3522 1 230117_WJC_METTL3_WT_vs_EV_F02.20189.20189.2 8.51E-06 24-Dec R.FSPLMTAAVLGTR.G "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 1362.733 1.15 16081 20189 2 1362.732759 682.3738 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 9.75 3762.1 - 835657 - - - -0.1453 - 2.376 0.499 - 438.8 1 2 0 -0.0002 13 0 0 0 2.15E+06 1.87E+06 - - - 4.9477 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.20190.20190.2 0.00689 18-Aug R.SAVVEMLIMR.G "sp|Q13418|ILK_HUMAN,tr|A0A087WWY6|A0A087WWY6_HUMAN,tr|A0A0A0MTH3|A0A0A0MTH3_HUMAN" 3 1147.6093 -1 16082 20190 2 1147.613953 574.8119 Integrin-linked protein kinase OS=Homo sapiens OX=9606 GN=ILK PE=1 SV=2 5.72 3762.2 - 693155 - - - 4.0231 - 1.716 0.382 - 207.4 1 2 0 0.0046 10 0 0 0 0.00E+00 0.00E+00 - - - 3.3683 1 230117_WJC_METTL3_WT_vs_EV_F02.20192.20192.2 1.55E-05 14/24 R.ALDPAAAAYLFQR.Q "sp|O75376|NCOR1_HUMAN,tr|E7EVK1|E7EVK1_HUMAN" 2 1405.7354 -1 16084 20192 2 1405.731895 703.875 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 5.88 3762.5 - 493083 - - - -2.4934 - 2.978 0.47 - 976.9 1 2 0 -0.0035 13 0 0 0 0.00E+00 0.00E+00 - - - 5.312 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20193.20193.2 0.00119 24-Sep K.LGNLFLNEDLEVK[136.11].L sp|P53350|PLK1_HUMAN 1 1510.8123 -1 16085 20193 2 1510.814418 756.4134 Serine\threonine-protein kinase PLK1 OS=Homo sapiens OX=9606 GN=PLK1 PE=1 SV=1 4.14 3762.6 - 488106 - - - 1.4284 - 1.567 0.382 - 244.6 1 2 0 0.0022 13 0 0 0 0.00E+00 0.00E+00 - - - 3.0146 1 230117_WJC_METTL3_WT_vs_EV_F02.20202.20202.2 0.000677 18-Dec R.LTTLELLEVR[166.11].R "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1195.7052 0.74 16093 20202 2 1195.709286 598.8599 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.53 3763.7 - 3.53E+06 - - - 3.4515 - 2.387 0.456 - 661.4 1 2 0 0.0041 10 0 0 0 1.16E+07 1.56E+07 - - - 4.8363 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.20204.20204.2 0.0069 18/22 R.ALLANALTSALR[166.11].L "sp|P57088|TMM33_HUMAN,tr|D6RAA6|D6RAA6_HUMAN" 2 1222.7273 1.16 16095 20204 2 1222.732254 612.3709 Transmembrane protein 33 OS=Homo sapiens OX=9606 GN=TMEM33 PE=1 SV=2 9.79 3763.9 - 2.21E+06 - - - 4.059 - 2.629 0.275 - 1663.5 1 2 0 0.005 12 0 0 0 6.64E+06 5.73E+06 - - - 3.6139 1 230117_WJC_METTL3_WT_vs_EV_F02.20205.20205.2 0.0175 18-Dec R.FC[160.03]IWTESAFR[166.11].K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1325.6102 -1 16096 20205 2 1325.614962 663.8124 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3764.1 - 2.14E+06 - - - 3.5825 - 2.23 0.45 - 634.2 1 2 0 0.0047 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6018 1 230117_WJC_METTL3_WT_vs_EV_F02.20207.20207.2 0.00375 18-Dec R.FC[160.03]IWTESAFR.K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1315.6019 0.84 16098 20207 2 1315.606602 658.8082 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3764.3 - 1.38E+06 - - - 3.5413 - 2.393 0.483 - 661.5 1 2 0 0.0047 10 0 0 0 6.32E+06 7.54E+06 - - - 5.0425 0.9824 230117_WJC_METTL3_WT_vs_EV_F02.20209.20209.2 0.241 12-Jul R.IIWQFIK.E "sp|P48735|IDHP_HUMAN,tr|H0YL11|H0YL11_HUMAN" 2 946.564 3.08 16100 20209 2 946.568061 474.2893 "Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2" 8.75 3764.6 - 1.20E+06 - - - 4.2649 - 1.245 0.185 - 120 1 2 0 0.004 7 0 0 0 3.01E+06 9.78E+05 - - - 1.1005 1 230117_WJC_METTL3_WT_vs_EV_F02.20210.20210.2 1.02E-06 16/26 K.LLTGELLPTDGMIR.K sp|Q9UG63|ABCF2_HUMAN 1 1527.8331 -1 16101 20210 2 1527.838192 764.9238 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.37 3764.7 - 1.12E+06 - - - 3.3557 - 2.966 0.504 - 679.1 1 2 0 0.0051 14 0 0 0 0.00E+00 0.00E+00 - - - 5.4902 1 230117_WJC_METTL3_WT_vs_EV_F02.20211.20211.2 2.12E-09 17/28 L.LVSVSALTLATETVR.S sp|P50991|TCPD_HUMAN 1 1558.893 136.13 16102 20211 2 1558.897309 780.4538 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6 3764.8 - 885088 - - - 2.7494 - 3.089 0.644 - 1055.9 1 1 0 0.0043 15 0 0 0 6.71E+07 4.93E+05 - - - 6.5691 1 230117_WJC_METTL3_WT_vs_EV_F02.20212.20212.2 0.000626 16/26 K.ALLAVIGADSVTLK.N sp|Q9NYH9|UTP6_HUMAN 1 1369.8181 1.32 16103 20212 2 1369.822546 685.9163 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3765 - 708987 - - - 3.2698 - 2.965 0.428 - 1038.5 1 2 0 0.0045 14 0 0 0 1.81E+06 1.37E+06 - - - 4.9283 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20217.20217.2 0.0253 13/26 K.ALLAVIGADSVTLK[136.11].N sp|Q9NYH9|UTP6_HUMAN 1 1377.8323 -1 16108 20217 2 1377.836484 689.9234 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3765.6 - 544733 - - - 3.0606 - 2.501 0.339 - 650.4 1 2 0 0.0042 14 0 0 0 0.00E+00 0.00E+00 - - - 3.8439 0.9973 230117_WJC_METTL3_WT_vs_EV_F02.20218.20218.2 0.0314 14-Sep K.EILIPVFK[136.11].N sp|P53396|ACLY_HUMAN 1 965.6041 1.39 16109 20218 2 965.608256 483.8093 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3765.8 - 542282 - - - 4.2989 - 1.422 0.379 - 260.4 1 2 0 0.0042 8 0 0 0 2.15E+07 1.55E+07 - - - 2.9008 0.973 230117_WJC_METTL3_WT_vs_EV_F02.20219.20219.2 1.17 12-Jul R.TLLEFLK[136.11].R "sp|Q14232|EI2BA_HUMAN,tr|F5H0D0|F5H0D0_HUMAN,tr|H0YGG4|H0YGG4_HUMAN" 3 870.5306 -1 16110 20219 2 870.534287 436.2726 Translation initiation factor eIF-2B subunit alpha OS=Homo sapiens OX=9606 GN=EIF2B1 PE=1 SV=1 5.66 3765.9 - 474813 - - - 4.2296 - 1.319 0.114 - 158 1 2 0 0.0037 7 0 0 0 0.00E+00 0.00E+00 - - - 0.7591 0.9908 230117_WJC_METTL3_WT_vs_EV_F02.20221.20221.2 0.329 14-Jul -.MLPLSLLK[136.11].T "sp|Q9Y4Z0|LSM4_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 921.5813 7.98 16111 20221 2 921.581368 461.7979 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 8.5 3766.2 - 224468 - - - 0.1161 - 1.049 0.214 - 120.9 1 2 0 0.0001 8 0 0 0 2.18E+07 2.73E+06 - - - 0.7658 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20223.20223.2 0.09 14-Aug K.EILIPVFK.N sp|P53396|ACLY_HUMAN 1 957.5899 1.39 16113 20223 2 957.59054 479.8022 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3766.3 - 2.99E+06 - - - 0.6631 - 1.642 0.325 - 226.6 1 2 0 0.0006 8 0 0 0 2.15E+07 1.55E+07 - - - 2.9369 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20224.20224.2 0.000611 20-Nov R.ELGLGLGLGLK.E "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 1068.6543 1.13 16114 20224 2 1068.656871 535.3344 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 6.1 3766.4 - 1.18E+06 - - - 2.4096 - 1.709 0.37 - 339.1 1 2 0 0.0026 11 0 0 0 5.70E+06 5.02E+06 - - - 3.2228 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20227.20227.2 0.000271 20-Nov R.ELGLGLGLGLK[136.11].E "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 1076.6685 1.13 16117 20227 2 1076.669321 539.3415 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 6.1 3766.6 - 963618 - - - 0.7663 - 1.719 0.495 - 362.2 1 2 0 0.0008 11 0 0 0 5.70E+06 5.02E+06 - - - 4.1624 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20228.20228.2 0.114 14-Aug K.QDILTIFK[136.11].R "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV8|B0QYV8_HUMAN" 2 984.5735 1.79 16118 20228 2 984.575068 493.294 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3766.6 - 739594 - - - 1.5591 - 1.766 0.28 - 221.1 1 2 0 0.0015 8 0 0 0 9.57E+06 5.35E+06 - - - 2.8238 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20231.20231.2 0.0001 20-Sep R.FSYLAVIEGAK[136.11].F "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 1204.6583 -1 16121 20231 2 1204.657333 603.3364 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 6 3766.9 - 536970 - - - -0.8235 - 1.713 0.502 - 184.3 1 2 0 -0.001 11 0 0 0 0.00E+00 0.00E+00 - - - 4.2045 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20234.20234.2 0.0185 18-Oct R.DLASVQALLR[166.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1094.6323 0.67 16124 20234 2 1094.633211 548.3234 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3767.2 - 399009 - - - 0.8067 - 1.946 0.348 - 299.1 1 2 0 0.0009 10 0 0 0 9.72E+06 1.45E+07 - - - 3.4694 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.20235.20235.2 0.398 12-Aug R.YGLVFFR.Q "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN,tr|F6WRY4|F6WRY4_HUMAN" 4 900.4858 1.22 16125 20235 2 900.485796 451.2502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.75 3767.3 - 376263 - - - 0.0244 - 1.704 0.249 - 221 1 2 0 0 7 0 0 0 2.78E+06 2.28E+06 - - - 2.5689 0.8656 230117_WJC_METTL3_WT_vs_EV_F02.20236.20236.2 0.101 22-Jun K.AAAIGIDLGTTY.S "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1164.6027 - 16126 20236 2 1164.604212 583.3086 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 3.8 3767.4 - 330924 - - - 1.3378 - 1.466 0.229 - 125.9 1 1 0 0.0016 12 0 0 0 - - - - - 1.7384 1 230117_WJC_METTL3_WT_vs_EV_F02.20238.20238.2 2.14E-05 13/24 K.ILTFDQLALDSPK.G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1459.7922 0.76 16128 20238 2 1459.794442 730.9034 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3767.5 - 302407 - - - 1.5043 - 2.714 0.569 - 602 1 2 0 0.0022 13 0 0 0 6.26E+07 8.28E+07 - - - 5.8054 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20242.20242.2 0.00384 20-Dec R.AFITNIPFDVK.W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1263.6863 2.62 16131 20242 2 1263.687853 632.8504 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3768 - 9.47E+07 - - - 1.21 - 2.142 0.455 - 557.1 1 2 0 0.0015 11 0 0 0 3.31E+08 1.26E+08 - - - 4.4618 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.20246.20246.2 0.00984 20-Sep R.VLPSIVNEVLK.S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1209.7333 1.41 16135 20246 2 1209.738136 605.8739 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3768.2 - 1.85E+06 - - - 4.0182 - 1.631 0.401 - 254.6 1 2 0 0.0049 11 0 0 0 1.02E+08 7.25E+07 - - - 3.3246 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20247.20247.2 0.00198 18-Oct K.LGLFPSNFVK.E sp|Q9Y5K6|CD2AP_HUMAN 1 1120.6281 1.58 16136 20247 2 1120.629882 561.3213 CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1 8.75 3768.3 - 1.65E+06 - - - 1.6071 - 1.888 0.324 - 218.8 1 2 0 0.0018 10 0 0 0 3.61E+06 2.28E+06 - - - 3.2074 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20248.20248.2 0.00268 18-Sep R.LFALVLTPTR.E sp|Q9H0S4|DDX47_HUMAN 1 1129.6859 1.02 16137 20248 2 1129.687748 565.8502 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 9.75 3768.5 - 1.40E+06 - - - 1.6093 - 2.067 0.292 - 227.1 1 2 0 0.0018 10 0 0 0 4.21E+06 4.11E+06 - - - 3.2239 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20249.20249.2 0.00741 18-Nov R.LFALVLTPTR[166.11].E sp|Q9H0S4|DDX47_HUMAN 1 1139.6942 1.06 16138 20249 2 1139.695378 570.8544 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 9.75 3768.6 - 1.26E+06 - - - 1.0336 - 2.252 0.399 - 474.3 1 2 0 0.0012 10 0 0 0 4.21E+06 3.99E+06 - - - 4.2537 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20251.20251.2 0.00136 12-Aug R.YGLVFFR[166.11].Q "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN,tr|F6WRY4|F6WRY4_HUMAN" 4 910.494 1.22 16140 20251 2 910.494378 456.2543 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.75 3768.8 - 1.09E+06 - - - 0.3668 - 1.773 0.377 - 280.4 1 2 0 0.0003 7 0 0 0 2.78E+06 2.28E+06 - - - 3.64 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.20252.20252.2 0.000448 16-Aug R.DGFVC[160.03]ALLR.F "sp|Q8WUY1|THEM6_HUMAN,tr|H0YAR9|H0YAR9_HUMAN" 2 1049.5328 -1 16141 20252 2 1049.531206 525.7737 Protein THEM6 OS=Homo sapiens OX=9606 GN=THEM6 PE=1 SV=2 5.83 3769 - 934716 - - - -1.5197 - 1.442 0.477 - 204.3 1 2 0 -0.0016 9 0 0 0 0.00E+00 0.00E+00 - - - 3.6226 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20256.20256.2 0.000681 18-Oct R.EYLLDMIPPR.S "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 3 1245.6427 3.38 16145 20256 2 1245.64642 623.8286 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.37 3769.5 - 604522 - - - 2.9503 - 1.9 0.413 - 339 1 2 0 0.0037 10 0 0 0 1.10E+07 3.26E+06 - - - 3.8819 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.20257.20257.3 0.0321 Dec-40 R.AFITNIPFDVK.W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1263.6863 4.47 16146 20257 3 1263.688654 422.2361 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3769.6 - 588547 - - - 1.8438 - 1.855 0.223 - 228.4 1 2 0 0.0023 11 0 0 0 1.15E+06 2.57E+05 - - - 2.7809 1 230117_WJC_METTL3_WT_vs_EV_F02.20260.20260.2 6.68E-07 14/28 K.ELVGPPLAETVFTPK.T sp|P49792|RBP2_HUMAN 1 1596.8763 2.21 16149 20260 2 1596.8806 799.4454 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3770 - 458306 - - - 2.6865 - 2.32 0.535 - 552.7 1 2 0 0.0043 15 0 0 0 8.73E+06 3.95E+06 - - - 5.0602 1 230117_WJC_METTL3_WT_vs_EV_F02.20265.20265.2 0.00469 20-Dec R.VLPSIVNEVLK[136.11].S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1217.7475 1.4 16153 20265 2 1217.752949 609.881 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3770.8 - 3.81E+06 - - - 4.4952 - 2.27 0.458 - 536.3 1 2 0 0.0055 11 0 0 0 1.02E+08 7.27E+07 - - - 4.6398 0.9943 230117_WJC_METTL3_WT_vs_EV_F02.20267.20267.2 0.549 14-Aug R.LLLTPWVK.F sp|Q14152|EIF3A_HUMAN 1 968.6059 0.9 16155 20267 2 968.609965 485.3102 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.75 3771 - 2.27E+06 - - - 4.2081 - 1.537 0.23 - 181.9 1 2 0 0.0041 8 0 0 0 8.33E+06 9.23E+06 - - - 2.0349 1 230117_WJC_METTL3_WT_vs_EV_F02.20270.20270.2 0.0256 15/20 R.IPDQLVILDMK.H "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1283.7159 1.35 16158 20270 2 1283.719952 642.8652 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.21 3771.4 - 1.02E+06 - - - 3.1487 - 2.954 0.449 - 1001.5 1 2 0 0.004 11 0 0 0 2.52E+07 1.87E+07 - - - 5.2862 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20271.20271.3 0.00475 Oct-44 R.LLHLPLSLTALK.L sp|Q9BTT6|LRRC1_HUMAN 1 1317.8384 2.88 16159 20271 3 1317.842855 440.2867 Leucine-rich repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRRC1 PE=1 SV=1 8.76 3771.5 - 1.00E+06 - - - 3.3745 - 2.05 0.382 - 173.2 1 2 0 0.0044 12 0 0 0 1.65E+06 5.74E+05 - - - 4.7874 1 230117_WJC_METTL3_WT_vs_EV_F02.20272.20272.2 0.000485 17/20 R.IPDQLVILDMK[136.11].H "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1291.7301 1.35 16160 20272 2 1291.732211 646.8723 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.21 3771.6 - 881666 - - - 1.6265 - 3.184 0.484 - 1464 1 2 0 0.0021 11 0 0 0 2.52E+07 1.87E+07 - - - 5.7482 0.998 230117_WJC_METTL3_WT_vs_EV_F02.20274.20274.2 0.000495 14-Jul R.FSLDFNLR.T "sp|Q96MM3|ZFP42_HUMAN,sp|P25490|TYY1_HUMAN,sp|O15391|TYY2_HUMAN,tr|H0YJV7|H0YJV7_HUMAN" 4 1010.5185 -1 16162 20274 2 1010.522763 506.2665 Zinc finger protein 42 homolog OS=Homo sapiens OX=9606 GN=ZFP42 PE=1 SV=2 5.84 3771.9 - 761998 - - - 4.1879 - 1.674 0.358 - 155 1 2 0 0.0042 8 0 0 0 0.00E+00 0.00E+00 - - - 3.2377 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.20276.20276.2 0.00124 18-Sep K.LQDMLDGFIK.K "sp|P55010|IF5_HUMAN,tr|H0YM54|H0YM54_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YMJ8|H0YMJ8_HUMAN,tr|H0YN40|H0YN40_HUMAN" 5 1178.6005 0.54 16164 20276 2 1178.604676 590.3075 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 4.21 3772.1 - 570890 - - - 3.5042 - 2.086 0.317 - 163.9 1 2 0 0.0041 10 0 0 0 1.72E+06 3.21E+06 - - - 3.4334 0.9626 230117_WJC_METTL3_WT_vs_EV_F02.20277.20277.2 0.0507 18-Jul R.ELIEMLAISR.N "sp|Q9NPJ6|MED4_HUMAN,tr|Q5T911|Q5T911_HUMAN" 2 1173.6427 -1 16165 20277 2 1173.652641 587.8286 Mediator of RNA polymerase II transcription subunit 4 OS=Homo sapiens OX=9606 GN=MED4 PE=1 SV=1 4.53 3772.3 - 508667 - - - 8.4319 - 1.697 0.289 - 120.3 1 2 0 0.0099 10 0 0 0 0.00E+00 0.00E+00 - - - 2.6487 0.9962 230117_WJC_METTL3_WT_vs_EV_F02.20287.20287.2 0.151 16-Aug K.LGFMSAFVK.A "sp|P36957|ODO2_HUMAN,tr|Q86SW4|Q86SW4_HUMAN" 2 998.5259 -1 16174 20287 2 998.526632 500.2702 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 8.75 3773.5 - 760729 - - - 0.709 - 1.432 0.158 - 122.8 1 2 0 0.0007 9 0 0 0 0.00E+00 0.00E+00 - - - 1.2466 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.20289.20289.2 7.08E-05 14-Aug R.DWVLNEFR[166.11].S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1087.5326 1.23 16176 20289 2 1087.536006 544.7736 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3773.7 - 726154 - - - 3.119 - 1.746 0.351 - 360.6 1 2 0 0.0034 8 0 0 0 2.91E+07 2.36E+07 - - - 3.3133 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20297.20297.3 0.00348 Sep-40 K.LLPQFLLHLDK[136.11].L "sp|Q8N4J0|CARME_HUMAN,tr|Q5T8V1|Q5T8V1_HUMAN,tr|Q5T8U9|Q5T8U9_HUMAN" 3 1343.8057 -1 16184 20297 3 1343.809355 448.9425 Carnosine N-methyltransferase OS=Homo sapiens OX=9606 GN=CARNMT1 PE=1 SV=1 6.74 3774.7 - 298855 - - - 2.7511 - 1.773 0.34 - 98 1 2 0 0.0037 11 0 0 0 0.00E+00 0.00E+00 - - - 3.9565 1 230117_WJC_METTL3_WT_vs_EV_F02.20299.20299.2 3.83E-07 16/28 K.ELVGPPLAETVFTPK[136.11].T sp|P49792|RBP2_HUMAN 1 1604.8905 2.21 16186 20299 2 1604.896671 803.4525 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3775 - 219224 - - - 3.8389 - 2.5 0.564 - 667.1 1 2 0 0.0062 15 0 0 0 8.73E+06 3.95E+06 - - - 5.4575 0.9913 230117_WJC_METTL3_WT_vs_EV_F02.20302.20302.2 0.126 12-Aug R.FVFLLDR.G sp|Q13045|FLII_HUMAN 1 908.512 1.96 16189 20302 2 908.514856 455.2633 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3775.4 - 172037 - - - 3.1557 - 1.63 0.067 - 247.3 1 2 0 0.0029 7 0 0 0 1.23E+07 6.25E+06 - - - 1.0831 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.20303.20303.2 0.00695 13/24 R.LAALPNVYEVISK[136.11].S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1423.8166 3.34 16190 20303 2 1423.822862 712.9156 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3775.5 - 169788 - - - 4.3861 - 2.374 0.377 - 437.2 1 2 0 0.0062 13 0 0 0 7.24E+06 2.17E+06 - - - 4.0425 0.9942 230117_WJC_METTL3_WT_vs_EV_F02.20305.20305.2 0.0806 16-Oct K.LGFMSAFVK[136.11].A "sp|P36957|ODO2_HUMAN,tr|Q86SW4|Q86SW4_HUMAN" 2 1006.5401 0.91 16191 20305 2 1006.543619 504.2773 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 8.75 3775.9 - 1.58E+06 - - - 3.4723 - 1.34 0.228 - 180.6 1 2 0 0.0035 9 0 0 0 2.77E+06 3.04E+06 - - - 1.5706 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.20307.20307.2 0.0167 14-Aug R.DWVLNEFR.S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1077.5243 1.24 16193 20307 2 1077.528316 539.7694 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3776 - 8.73E+06 - - - 3.6862 - 1.823 0.357 - 364.7 1 2 0 0.004 8 0 0 0 2.91E+07 2.35E+07 - - - 3.4876 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20311.20311.2 9.22E-07 16-Oct K.MTILQTYFR.Q sp|O75348|VATG1_HUMAN 1 1171.606 0.68 16197 20311 2 1171.609401 586.8103 V-type proton ATPase subunit G 1 OS=Homo sapiens OX=9606 GN=ATP6V1G1 PE=1 SV=3 8.5 3776.4 - 1.95E+06 - - - 2.9327 - 2.196 0.401 - 292.2 1 2 0 0.0034 9 0 0 0 4.20E+06 6.19E+06 - - - 4.2775 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.20314.20314.2 0.00824 13/24 R.LAALPNVYEVISK.S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1415.8024 3.34 16200 20314 2 1415.80706 708.9085 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3776.7 - 1.46E+06 - - - 3.2794 - 2.386 0.303 - 421.4 1 2 0 0.0046 13 0 0 0 7.24E+06 2.17E+06 - - - 3.5094 0.9905 230117_WJC_METTL3_WT_vs_EV_F02.20315.20315.2 0.0291 12-Jul R.FVFLLDR[166.11].G sp|Q13045|FLII_HUMAN 1 918.5203 1.96 16201 20315 2 918.52262 460.2674 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3776.8 - 1.46E+06 - - - 2.5704 - 1.46 0.071 - 196.5 1 2 0 0.0024 7 0 0 0 1.23E+07 6.25E+06 - - - 0.7638 1 230117_WJC_METTL3_WT_vs_EV_F02.20318.20318.2 6.93E-08 17/26 K.LLAESVTEVEIFGK.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1533.829 1.26 16204 20318 2 1533.832913 767.9218 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 3777.2 - 1.10E+06 - - - 2.5342 - 3.252 0.555 - 865.3 1 2 0 0.0039 14 0 0 0 6.43E+06 5.10E+06 - - - 6.0983 1 230117_WJC_METTL3_WT_vs_EV_F02.20319.20319.2 9.81E-06 16/26 K.LLAESVTEVEIFGK[136.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1541.8432 1.24 16205 20319 2 1541.847143 771.9289 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 3777.4 - 1.05E+06 - - - 2.5405 - 3.004 0.55 - 789.3 1 2 0 0.0039 14 0 0 0 6.43E+06 5.19E+06 - - - 5.8623 1 230117_WJC_METTL3_WT_vs_EV_F02.20322.20322.2 7.05E-07 13/20 K.IVFAAGNFWGR.T sp|P04181|OAT_HUMAN 1 1236.6404 -1 16208 20322 2 1236.645935 619.3275 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 9.75 3777.7 - 865932 - - - 4.4944 - 2.398 0.549 - 539.9 1 2 0 0.0056 11 0 0 0 0.00E+00 0.00E+00 - - - 5.4603 1 230117_WJC_METTL3_WT_vs_EV_F02.20323.20323.2 1.28E-08 15/36 R.YEGILYTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2100.0627 -1 16209 20323 2 2100.070612 1051.0386 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3777.9 - 791618 - - - 3.7832 - 3.251 0.597 - 429 1 2 0 0.0079 19 0 0 0 0.00E+00 0.00E+00 - - - 6.3465 1 230117_WJC_METTL3_WT_vs_EV_F02.20324.20324.2 2.46E-13 19/36 R.YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2108.0769 -1 16210 20324 2 2108.082004 1055.0457 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3778 - 636507 - - - 2.4368 - 3.759 0.695 - 930 1 2 0 0.0051 19 0 0 0 0.00E+00 0.00E+00 - - - 7.4281 0.9908 230117_WJC_METTL3_WT_vs_EV_F02.20327.20327.2 0.00213 16-Aug R.DSVVLSLLK[136.11].Q sp|O43264|ZW10_HUMAN 1 980.5997 0.86 16212 20327 2 980.605191 491.3072 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 5.84 3778.3 - 119265 - - - 5.5507 - 1.604 0.282 - 187.1 1 2 0 0.0054 9 0 0 0 2.51E+06 2.93E+06 - - - 2.4891 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20328.20328.2 0.0227 18-Jul K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.57 16213 20328 2 1168.708488 585.3606 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3778.3 - 6.95E+06 - - - 1.5085 - 1.43 0.41 - 134 1 2 0 0.0018 10 0 0 0 2.25E+09 1.43E+09 - - - 3.0671 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20329.20329.2 0.102 18-Sep K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.57 16214 20329 2 1176.722451 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3778.4 - 5.35E+06 - - - 1.2968 - 1.986 0.365 - 209.7 1 2 0 0.0015 10 0 0 0 2.25E+09 1.43E+09 - - - 3.6516 0.9496 230117_WJC_METTL3_WT_vs_EV_F02.20333.20333.2 0.00783 18-Jul R.VLQDFYLELR[166.11].K "sp|Q9UJA3|MCM8_HUMAN,tr|A0A494C100|A0A494C100_HUMAN" 2 1304.7004 -1 16218 20333 2 1304.711943 653.3575 DNA helicase MCM8 OS=Homo sapiens OX=9606 GN=MCM8 PE=1 SV=2 4.37 3778.7 - 139996 - - - 8.8411 - 1.75 0.245 - 234.3 1 2 0 0.0115 10 0 0 0 0.00E+00 0.00E+00 - - - 2.409 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.20348.20348.2 0.0564 14-Sep K.VNLAELFK.G sp|P30044|PRDX5_HUMAN 1 932.5331 2.06 16231 20348 2 932.532349 467.2738 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.97 3780.6 - 2.28E+07 - - - -0.8246 - 2.02 0.356 - 280.6 1 2 0 -0.0008 8 0 0 0 1.40E+08 6.81E+07 - - - 3.7907 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.20349.20349.2 0.00141 14-Jul K.VNLAELFK[136.11].G sp|P30044|PRDX5_HUMAN 1 940.5473 2.05 16232 20349 2 940.54645 471.2809 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.97 3780.6 - 1.05E+07 - - - -0.9229 - 1.713 0.356 - 137.7 1 2 0 -0.0009 8 0 0 0 1.41E+08 6.85E+07 - - - 3.2935 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20350.20350.2 0.0016 18-Dec R.VDILDPALLR.S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1123.6601 1.84 16233 20350 2 1123.661256 562.8373 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3780.7 - 4.71E+06 - - - 1.0199 - 2.531 0.399 - 454.5 1 2 0 0.0011 10 0 0 0 6.42E+07 3.50E+07 - - - 4.5797 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20352.20352.3 0.00852 Dec-36 K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.66 16235 20352 3 1168.704828 390.5762 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3780.9 - 2.93E+06 - - - -1.6232 - 2.233 0.351 - 182.3 1 2 0 -0.0019 10 0 0 0 5.83E+06 3.51E+06 - - - 4.7989 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20353.20353.2 0.177 18-Dec R.VDILDPALLR[166.11].S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1133.6684 1.84 16236 20353 2 1133.669741 567.8415 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3781.1 - 2.81E+06 - - - 1.2005 - 2.305 0.32 - 457.2 1 2 0 0.0014 10 0 0 0 6.42E+07 3.50E+07 - - - 3.7351 1 230117_WJC_METTL3_WT_vs_EV_F02.20354.20354.2 0.000338 13/22 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 3102.34 16237 20354 2 1603.76091 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3781.2 - 2.53E+06 - - - -1.8893 - 2.043 0.532 - 433.9 1 2 0 -0.003 12 0 0 0 4.05E+09 1.30E+06 - - - 4.8492 0.9812 230117_WJC_METTL3_WT_vs_EV_F02.20355.20355.3 3.68 Nov-36 K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.66 16238 20355 3 1176.718313 393.2476 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3781.3 - 2.05E+06 - - - -2.2197 - 1.9 0.163 - 141.7 1 2 0 -0.0026 10 0 0 0 5.83E+06 3.51E+06 - - - 2.2311 1 230117_WJC_METTL3_WT_vs_EV_F02.20356.20356.2 2.17E-05 14/22 R.GNSIIMLEALER.V "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1344.7071 1.1 16239 20356 2 1344.704309 673.3608 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3781.4 - 1.82E+06 - - - -2.1023 - 2.709 0.552 - 842 1 2 0 -0.0028 12 0 0 0 1.41E+07 1.28E+07 - - - 5.7394 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.20357.20357.2 0.00712 14-Aug R.YLIYDIIK.F sp|O60942|MCE1_HUMAN 1 1039.5954 171.5 16240 20357 2 1039.59324 520.805 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 5.83 3781.6 - 1.64E+06 - - - -2.0623 - 1.433 0.354 - 187.7 1 2 0 -0.0021 8 0 0 0 9.22E+06 5.37E+04 - - - 2.74 0.9722 230117_WJC_METTL3_WT_vs_EV_F02.20358.20358.2 1.78 12-Jul K.YLFTLIR.A sp|P57740|NU107_HUMAN 1 924.5433 1.18 16241 20358 2 924.545386 463.2789 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 8.75 3781.7 - 1.57E+06 - - - 2.2681 - 1.105 0.076 - 175.4 1 2 0 0.0021 7 0 0 0 1.23E+07 1.04E+07 - - - -0.082 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.20359.20359.2 0.0789 14-Nov K.QFLPFLQR.A "sp|Q7KZF4|SND1_HUMAN,tr|H7C597|H7C597_HUMAN" 2 1047.5866 1.42 16242 20359 2 1047.585863 524.8006 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 9.75 3781.8 - 1.43E+06 - - - -0.6567 - 1.985 0.267 - 505.8 1 2 0 -0.0007 8 0 0 0 1.76E+07 1.24E+07 - - - 3.0806 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20360.20360.2 0.00352 18-Oct R.GLAVFISDIR[166.11].N "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|M0R2D9|M0R2D9_HUMAN,tr|E9PR62|E9PR62_HUMAN" 4 1099.6265 1.72 16243 20360 2 1099.625967 550.8205 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 5.84 3782 - 1.14E+06 - - - -0.4984 - 2.098 0.404 - 398.5 1 2 0 -0.0005 10 0 0 0 1.09E+07 6.31E+06 - - - 4.0931 0.9776 230117_WJC_METTL3_WT_vs_EV_F02.20361.20361.2 0.845 22-Oct R.SFTPVFLGSALK[136.11].N "sp|Q96RP9|EFGM_HUMAN,tr|F8WAU4|F8WAU4_HUMAN,tr|C9IZ01|C9IZ01_HUMAN" 3 1273.7162 1.62 16244 20361 2 1273.719909 637.8654 "Elongation factor G, mitochondrial OS=Homo sapiens OX=9606 GN=GFM1 PE=1 SV=2" 8.47 3782.1 - 1.11E+06 - - - 2.9324 - 1.254 0.09 - 204 1 2 0 0.0037 12 0 0 0 1.58E+07 9.77E+06 - - - 0.3001 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.20362.20362.2 1.2 20-Oct R.LEYC[160.03]EALAMLR.E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1367.6577 1.13 16245 20362 2 1367.656748 684.8361 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3782.2 - 1.09E+06 - - - -0.7275 - 1.93 0.185 - 393.9 1 2 0 -0.001 11 0 0 0 7.50E+06 6.61E+06 - - - 2.1858 1 230117_WJC_METTL3_WT_vs_EV_F02.20363.20363.2 0.0068 13/20 R.LEYC[160.03]EALAMLR[166.11].E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1377.666 -1 16246 20363 2 1377.660642 689.8403 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3782.4 - 851230 - - - -3.8986 - 2.513 0.436 - 878.9 1 2 0 -0.0054 11 0 0 0 0.00E+00 0.00E+00 - - - 4.7524 1 230117_WJC_METTL3_WT_vs_EV_F02.20367.20367.2 7.29E-06 16/24 R.LPSDVVTGYLALR.K "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1402.782 1.44 16250 20367 2 1402.776995 702.3983 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 5.84 3782.9 - 686591 - - - -3.5793 - 2.916 0.515 - 1136.2 1 2 0 -0.005 13 0 0 0 3.55E+06 2.46E+06 - - - 5.5899 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20371.20371.3 0.001 Jul-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 1947.88 16253 20371 3 1603.765056 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3783.3 - 2.71E+06 - - - 0.6959 - 1.514 0.376 - 82.6 1 2 0 0.0011 12 0 0 0 8.06E+08 4.14E+05 - - - 3.8814 1 230117_WJC_METTL3_WT_vs_EV_F02.20386.20386.2 0.0574 15/24 R.LAAVALINAAIQK.G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1294.7973 1.18 16266 20386 2 1294.795925 648.4059 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3785 - 772070 - - - -1.0403 - 3.231 0.352 - 803.5 1 2 0 -0.0013 13 0 0 0 3.68E+06 3.11E+06 - - - 4.6505 0.999 230117_WJC_METTL3_WT_vs_EV_F02.20387.20387.2 0.0012 16-Jul R.SIQMLTLLR.A "sp|Q13445|TMED1_HUMAN,tr|K7EIN4|K7EIN4_HUMAN,tr|K7EQ63|K7EQ63_HUMAN" 3 1073.6267 1.05 16267 20387 2 1073.629698 537.8206 Transmembrane emp24 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TMED1 PE=1 SV=1 9.47 3785.1 - 1.73E+06 - - - 2.7915 - 1.727 0.317 - 153.6 1 2 0 0.003 9 0 0 0 4.63E+06 4.41E+06 - - - 2.9621 1 230117_WJC_METTL3_WT_vs_EV_F02.20390.20390.2 0.0133 18-Dec R.LSDYLFTLAR.Y "sp|Q96EY8|MMAB_HUMAN,tr|S4R3P5|S4R3P5_HUMAN" 2 1197.6394 3.15 16270 20390 2 1197.640488 599.827 Corrinoid adenosyltransferase OS=Homo sapiens OX=9606 GN=MMAB PE=1 SV=1 5.84 3785.5 - 1.53E+06 - - - 0.9302 - 2.422 0.474 - 480.1 1 2 0 0.0011 10 0 0 0 3.09E+06 9.82E+05 - - - 5.0108 0.9685 230117_WJC_METTL3_WT_vs_EV_F02.20393.20393.2 1.61E-07 13/26 R.IGPYQPNVPVGIDY.V "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1530.7718 - 16273 20393 2 1530.771711 766.3932 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 3.8 3785.8 - 1.25E+06 - - - -0.0875 - 2.157 0.47 - 383.5 1 1 0 -0.0001 14 0 0 0 - - - - - 4.4414 0.9916 230117_WJC_METTL3_WT_vs_EV_F02.20394.20394.2 0.108 16-May R.FLYIWPNAR[166.11].L "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HKH3|A0A804HKH3_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 11 1188.6319 1.78 16274 20394 2 1188.631047 595.3232 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 8.75 3786 - 1.03E+06 - - - -0.7462 - 1.177 0.231 - 69.7 1 2 0 -0.0009 9 0 0 0 6.89E+06 3.87E+06 - - - 1.2184 0.9335 230117_WJC_METTL3_WT_vs_EV_F02.20396.20396.2 0.952 12-May R.YMDLLWR.Y "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 995.4899 0.66 16276 20396 2 995.492676 498.7522 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 5.84 3786.2 - 713260 - - - 2.8157 - 0.829 0.146 - 54.5 1 2 0 0.0028 7 0 0 0 2.67E+06 4.03E+06 - - - -0.4757 0.9931 230117_WJC_METTL3_WT_vs_EV_F02.20398.20398.2 6.07 14-Aug R.SGLLGELR.N "sp|O60336|MABP1_HUMAN,tr|D6RHX7|D6RHX7_HUMAN" 2 843.4814 11.11 16278 20398 2 843.482279 422.748 Mitogen-activated protein kinase-binding protein 1 OS=Homo sapiens OX=9606 GN=MAPKBP1 PE=1 SV=4 5.72 3786.5 - 665924 - - - 1.022 - 1.369 0.104 - 192.8 1 2 0 0.0009 8 0 0 0 8.60E+06 7.74E+05 - - - 0.7561 0.995 230117_WJC_METTL3_WT_vs_EV_F02.20399.20399.2 0.00979 22-Aug R.LLVFGGMVEYGK[136.11].Y "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 1319.7039 1.81 16279 20399 2 1319.702079 660.8592 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 6 3786.6 - 634322 - - - -1.3761 - 1.516 0.254 - 180.1 1 2 0 -0.0018 12 0 0 0 2.82E+06 1.56E+06 - - - 2.0112 1 230117_WJC_METTL3_WT_vs_EV_F02.20400.20400.2 5.76E-06 14/24 R.LAAVALINAAIQK[136.11].G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1302.8115 1.18 16280 20400 2 1302.811196 652.413 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3786.7 - 531209 - - - -0.2118 - 3.045 0.481 - 692.3 1 2 0 -0.0003 13 0 0 0 3.68E+06 3.11E+06 - - - 5.4514 0.8541 230117_WJC_METTL3_WT_vs_EV_F02.20406.20406.2 0.011 12-Jul Y.TLLWPLR.D sp|Q14166|TTL12_HUMAN 1 897.5436 4.78 16285 20406 2 897.544425 449.7791 Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens OX=9606 GN=TTLL12 PE=1 SV=2 9.41 3787.6 - 22729.5 - - - 0.8935 - 1.41 0.212 - 213.7 1 1 0 0.0008 7 0 0 0 4.68E+06 9.78E+05 - - - 1.6953 1 230117_WJC_METTL3_WT_vs_EV_F02.20413.20413.2 4.47E-10 16/24 R.WSTLVEDYGMELR.K sp|O00232|PSD12_HUMAN 1 1597.7446 0.04 16291 20413 2 1597.748263 799.8796 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.14 3788.5 - 802027 - - - 2.2651 - 2.784 0.671 - 1050.2 1 2 0 0.0036 13 0 0 0 4.19E+06 1.05E+08 - - - 6.6237 0.9892 230117_WJC_METTL3_WT_vs_EV_F02.20414.20414.2 1.59 12-May R.EFALWLK.D "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 905.5011 0.81 16292 20414 2 905.50204 453.7578 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 6.1 3788.6 - 770676 - - - 1.0491 - 1.22 0.103 - 124.4 1 2 0 0.001 7 0 0 0 2.28E+06 2.82E+06 - - - 0.4315 1 230117_WJC_METTL3_WT_vs_EV_F02.20415.20415.2 2.44E-05 20-Dec K.SIDPALSMLIK.S sp|Q9H501|ESF1_HUMAN 1 1186.6631 1.3 16293 20415 2 1186.659643 594.3388 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 5.55 3788.8 - 729660 - - - -2.952 - 2.256 0.493 - 334.7 1 2 0 -0.0035 11 0 0 0 2.50E+06 1.92E+06 - - - 4.8822 1 230117_WJC_METTL3_WT_vs_EV_F02.20417.20417.2 5.06E-08 17/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 16295 20417 2 1343.611013 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3789 - 607280 - - - -0.3342 - 2.964 0.543 - 1152.3 1 1 0 -0.0004 10 0 0 0 2.87E+07 0.00E+00 - - - 6.0843 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20419.20419.2 0.00447 18-Aug K.NGFLLDGFPR[166.11].T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1144.5905 1.3 16297 20419 2 1144.591805 573.3025 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3789.3 - 582395 - - - 1.1716 - 1.682 0.385 - 163.7 1 2 0 0.0013 10 0 0 0 8.57E+06 6.61E+06 - - - 3.3356 1 230117_WJC_METTL3_WT_vs_EV_F02.20420.20420.2 0.000585 13/22 K.TVLLLADQMISR.L "sp|P48730|KC1D_HUMAN,sp|P49674|KC1E_HUMAN,tr|B0QY36|B0QY36_HUMAN,tr|B0QY34|B0QY34_HUMAN,tr|H7BYT1|H7BYT1_HUMAN,tr|J3QQI9|J3QQI9_HUMAN,tr|A0A669KBC0|A0A669KBC0_HUMAN,tr|H0Y645|H0Y645_HUMAN,tr|B0QY35|B0QY35_HUMAN,tr|H0Y2N6|H0Y2N6_HUMAN" 10 1358.7592 1.96 16298 20420 2 1358.76023 680.3869 Casein kinase I isoform delta OS=Homo sapiens OX=9606 GN=CSNK1D PE=1 SV=2 5.5 3789.4 - 542746 - - - 0.7787 - 2.784 0.471 - 697.1 1 2 0 0.0011 12 0 0 0 3.57E+06 1.82E+06 - - - 5.2135 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.20423.20423.2 0.000215 18-Aug K.LVFPQDLLEK[136.11].G "sp|Q8TCT9|HM13_HUMAN,tr|A0A3B3IT72|A0A3B3IT72_HUMAN,tr|A0A0S2Z6F0|A0A0S2Z6F0_HUMAN,tr|A0A3B3IUB5|A0A3B3IUB5_HUMAN,tr|A0A075B6F6|A0A075B6F6_HUMAN" 5 1208.6896 1.83 16301 20423 2 1208.694132 605.3521 Minor histocompatibility antigen H13 OS=Homo sapiens OX=9606 GN=HM13 PE=1 SV=1 4.37 3789.8 - 478126 - - - 3.7288 - 1.553 0.352 - 167 1 2 0 0.0045 10 0 0 0 6.29E+06 3.44E+06 - - - 2.8682 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20424.20424.2 0.13 20-Dec R.VYGALMWSLGK.V "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|C9JDQ8|C9JDQ8_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 7 1223.6373 3.68 16302 20424 2 1223.637999 612.8259 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 8.56 3789.9 - 393108 - - - 0.599 - 2.154 0.383 - 408.8 1 2 0 0.0007 11 0 0 0 6.39E+06 1.74E+06 - - - 3.9454 1 230117_WJC_METTL3_WT_vs_EV_F02.20426.20426.2 3.82E-05 24-Dec R.TLVSGLLLEDSVR.V sp|A0A2Z4LIS9|FXO3B_HUMAN 1 1400.7875 2.46 16304 20426 2 1400.785071 701.401 Forkhead box protein O3B OS=Homo sapiens OX=9606 GN=FOXO3B PE=1 SV=1 4.37 3790.2 - 260483 - - - -1.7305 - 2.361 0.493 - 386.2 1 2 0 -0.0024 13 0 0 0 1.54E+06 6.29E+05 - - - 4.8864 0.9773 230117_WJC_METTL3_WT_vs_EV_F02.20430.20430.2 1.08 20-Sep R.VYGALMWSLGK[136.11].V "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|C9JDQ8|C9JDQ8_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 7 1231.6515 3.76 16307 20430 2 1231.648762 616.833 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 8.56 3790.7 - 614107 - - - -2.1954 - 1.391 0.165 - 168.5 1 2 0 -0.0027 11 0 0 0 6.53E+06 1.74E+06 - - - 1.1516 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20433.20433.2 0.058 18-Aug K.INEWLTLVEK[136.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1251.6954 1.13 16310 20433 2 1251.696074 626.855 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.53 3790.9 - 1.92E+06 - - - 0.5073 - 2.109 0.249 - 325.6 1 2 0 0.0006 10 0 0 0 1.03E+07 9.13E+06 - - - 2.9628 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.20435.20435.2 0.00539 16-Sep K.ELALSALLK[136.11].F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 964.6048 0.95 16312 20435 2 964.60439 483.3097 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3791.1 - 1.58E+06 - - - -0.4593 - 1.797 0.349 - 274.1 1 2 0 -0.0004 9 0 0 0 2.20E+07 2.31E+07 - - - 3.3142 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20436.20436.2 0.00402 16-Sep K.ELALSALLK.F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 956.5906 0.95 16313 20436 2 956.590776 479.3026 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3791.1 - 1.34E+06 - - - 0.1495 - 1.785 0.322 - 248.3 1 2 0 0.0001 9 0 0 0 2.20E+07 2.31E+07 - - - 3.0955 0.9769 230117_WJC_METTL3_WT_vs_EV_F02.20437.20437.2 0.587 12-Jun K.LDDLFLK.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 862.48 1.98 16314 20437 2 862.479773 432.2473 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3791.2 - 852374 - - - -0.2864 - 1.474 0 - 114.1 1 2 0 -0.0002 7 0 0 0 6.24E+06 3.16E+06 - - - 0.2703 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.20438.20438.2 6.66E-05 16-Nov K.MAVLALLAK[136.11].L sp|P78527|PRKDC_HUMAN 1 936.5922 0.96 16315 20438 2 936.590823 469.3034 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.5 3791.3 - 649147 - - - -1.4275 - 2.117 0.34 - 354.4 1 2 0 -0.0013 9 0 0 0 1.69E+06 1.76E+06 - - - 3.7216 1 230117_WJC_METTL3_WT_vs_EV_F02.20453.20453.2 1.23E-10 30-Nov R.LMNDMTAVALNYGIYK.Q sp|Q92598|HS105_HUMAN 1 1815.8899 -1 16326 20453 2 1815.891451 908.9522 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.83 3792.9 - 0 - - - 0.8387 - 2.427 0.708 - 404.2 1 2 0 0.0015 16 0 0 0 0.00E+00 0.00E+00 - - - 6.4497 0.9961 230117_WJC_METTL3_WT_vs_EV_F02.20454.20454.2 0.438 12-May R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 2.3 16327 20454 2 808.432733 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 3793 - 0 - - - -0.4169 - 1.278 0.271 - 58 2 2 0 -0.0003 7 0 0 0 1.35E+07 5.86E+06 - - - 1.6853 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.20460.20460.2 9.21E-05 20-Nov K.GVPTGFILPIR[166.11].D "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1178.7051 5.02 16331 20460 2 1178.701061 590.3598 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 3793.7 - 5.71E+06 - - - -3.4258 - 1.869 0.43 - 346.6 1 2 0 -0.004 11 0 0 0 1.05E+08 2.09E+07 - - - 3.9076 0.9608 230117_WJC_METTL3_WT_vs_EV_F02.20463.20463.2 0.0163 12-Jul K.LWDLYLR.T "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 977.5335 1.57 16334 20463 2 977.53059 489.774 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.84 3794.1 - 2.63E+06 - - - -2.9278 - 1.544 0.089 - 211.1 1 2 0 -0.0029 7 0 0 0 6.93E+06 4.40E+06 - - - 1.0738 1 230117_WJC_METTL3_WT_vs_EV_F02.20464.20464.2 2.67E-10 18/30 K.IITLEEGDIILTGTPK.G sp|Q6P587|FAHD1_HUMAN 1 1711.9608 3.3 16335 20464 2 1711.95318 856.9877 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3794.2 - 2.53E+06 - - - -4.4323 - 3.526 0.642 - 967.9 1 2 0 -0.0076 16 0 0 0 5.93E+06 1.80E+06 - - - 6.8786 0.9835 230117_WJC_METTL3_WT_vs_EV_F02.20465.20465.2 6.15E-05 18-Nov R.VFGFSLITNK.V sp|P00491|PNPH_HUMAN 1 1124.623 3.06 16336 20465 2 1124.618676 563.3188 Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2 8.72 3794.4 - 1.86E+06 - - - -3.8413 - 1.676 0.254 - 331.7 1 2 0 -0.0043 10 0 0 0 8.25E+06 2.70E+06 - - - 2.3571 0.9502 230117_WJC_METTL3_WT_vs_EV_F02.20466.20466.2 0.442 12-Jul K.LWDLYLR[166.11].T "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 987.5417 1.54 16337 20466 2 987.538263 494.7781 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.84 3794.5 - 1.84E+06 - - - -3.5026 - 1.491 0.115 - 148.9 1 2 0 -0.0035 7 0 0 0 6.67E+06 4.32E+06 - - - 1.155 1 230117_WJC_METTL3_WT_vs_EV_F02.20467.20467.2 7.29E-05 22-Dec R.LLTFMGMAVENK[136.11].E "sp|Q7L2H7|EIF3M_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 2 1360.6974 0.77 16338 20467 2 1360.692156 681.356 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6 3794.6 - 1.82E+06 - - - -3.876 - 2.493 0.593 - 469.4 1 2 0 -0.0053 12 0 0 0 3.78E+06 4.91E+06 - - - 5.8228 1 230117_WJC_METTL3_WT_vs_EV_F02.20469.20469.2 0.00123 13/22 K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.8 16340 20469 2 1317.700458 659.862 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3794.9 - 1.66E+06 - - - -6.767 - 2.523 0.525 - 334.4 1 2 0 -0.0089 12 0 0 0 1.49E+08 1.87E+08 - - - 5.3509 1 230117_WJC_METTL3_WT_vs_EV_F02.20470.20470.2 0.263 24-Dec K.LILLITQVTASEK.T sp|Q15061|WDR43_HUMAN 1 1427.8599 -1 16341 20470 2 1427.855916 714.9372 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3795 - 1.63E+06 - - - -2.8126 - 2.515 0.449 - 404.6 1 2 0 -0.004 13 0 0 0 0.00E+00 0.00E+00 - - - 4.7231 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.20472.20472.3 0.000108 Dec-60 K.IITLEEGDIILTGTPK.G sp|Q6P587|FAHD1_HUMAN 1 1711.9608 -1 16343 20472 3 1711.959857 571.6609 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3795.3 - 1.41E+06 - - - -0.5321 - 2.521 0.479 - 205 1 2 0 -0.0009 16 0 0 0 0.00E+00 0.00E+00 - - - 6.2527 1 230117_WJC_METTL3_WT_vs_EV_F02.20476.20476.2 0.00225 30-Dec K.IITLEEGDIILTGTPK[136.11].G sp|Q6P587|FAHD1_HUMAN 1 1719.975 -1 16347 20476 2 1719.968546 860.9948 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3795.8 - 1.30E+06 - - - -3.7338 - 2.757 0.475 - 301.8 1 2 0 -0.0064 16 0 0 0 0.00E+00 0.00E+00 - - - 5.0407 1 230117_WJC_METTL3_WT_vs_EV_F02.20477.20477.2 8.54E-05 14/24 K.LILLITQVTASEK[136.11].T sp|Q15061|WDR43_HUMAN 1 1435.8741 -1 16348 20477 2 1435.869974 718.9443 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3795.9 - 1.14E+06 - - - -2.8958 - 3.048 0.482 - 652.2 1 2 0 -0.0042 13 0 0 0 0.00E+00 0.00E+00 - - - 5.4601 1 230117_WJC_METTL3_WT_vs_EV_F02.20482.20482.2 2.50E-06 22-Sep K.TVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1309.6952 0.8 16352 20482 2 1309.696005 655.8549 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3796.3 - 5.74E+06 - - - 0.6337 - 1.818 0.59 - 159.7 1 2 0 0.0008 12 0 0 0 1.49E+08 1.87E+08 - - - 4.9712 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.20483.20483.3 1.42E-06 Dec-44 K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.65 16353 20483 3 1317.708836 440.2437 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3796.4 - 4.50E+06 - - - -0.409 - 2.293 0.521 - 258.5 1 2 0 -0.0005 12 0 0 0 8.68E+06 1.34E+07 - - - 6.6487 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.20484.20484.2 0.0445 18-Aug K.AEVLWLMGAK.S sp|O94906|PRP6_HUMAN 1 1116.6002 0.77 16354 20484 2 1116.599713 559.3074 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.05 3796.4 - 1.47E+06 - - - -0.3932 - 1.611 0.359 - 152.8 1 2 0 -0.0004 10 0 0 0 9.02E+06 1.18E+07 - - - 3.0235 1 230117_WJC_METTL3_WT_vs_EV_F02.20487.20487.2 4.82E-07 14/26 R.WSSMEIMEAYSVAR.Q "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|Q5TG81|Q5TG81_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 5 1658.7433 0.92 16357 20487 2 1658.739486 830.3789 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 4.53 3796.7 - 0 - - - -2.2776 - 2.604 0.629 - 571.8 1 2 0 -0.0038 14 0 0 0 2.93E+06 3.19E+06 - - - 6.0873 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20489.20489.2 0.00215 22-Aug K.SLLVNPVLFPNR[166.11].E sp|Q9BUB7|TMM70_HUMAN 1 1377.8008 -1 16359 20489 2 1377.801193 689.9077 "Transmembrane protein 70, mitochondrial OS=Homo sapiens OX=9606 GN=TMEM70 PE=1 SV=2" 9.47 3796.9 - 0 - - - 0.2918 - 1.803 0.391 - 192.2 1 2 0 0.0004 12 0 0 0 0.00E+00 0.00E+00 - - - 3.4797 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20494.20494.2 0.00654 16-Aug K.EIIDLVLDR[166.11].L "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 9 1094.6211 3.3 16363 20494 2 1094.622431 548.3178 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.03 3797.4 - 4.97E+06 - - - 1.2205 - 1.746 0.438 - 290.8 1 2 0 0.0013 9 0 0 0 3.06E+08 9.27E+07 - - - 3.888 0.9591 230117_WJC_METTL3_WT_vs_EV_F02.20495.20495.2 2.21 20-Jun K.C[160.03]GPMVLDALIK.L "sp|P21912|SDHB_HUMAN,tr|A0A087WWT1|A0A087WWT1_HUMAN,tr|A0A087WXX8|A0A087WXX8_HUMAN" 3 1215.6356 0.92 16364 20495 2 1215.635419 608.8251 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.83 3797.5 - 0 - - - -0.1086 - 0.976 0.114 - 45.1 1 2 0 -0.0001 11 0 0 0 2.82E+06 3.08E+06 - - - -0.1828 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.20499.20499.2 0.0152 18-Oct K.VGDPVYLLGQ.- "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN" 2 1059.5601 - 16368 20499 2 1059.559728 530.7873 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 3.8 3798 - 896969 - - - -0.3143 - 1.877 0.265 - 314.3 1 2 0 -0.0003 10 0 0 0 - - - - - 2.7558 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.20502.20502.2 0.0254 24-Nov R.LELYAQATEALLK.T "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1461.8079 -1 16370 20502 2 1461.804729 731.9112 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 4.53 3798.3 - 0 - - - -2.1665 - 2.061 0.313 - 157.4 1 2 0 -0.0032 13 0 0 0 0.00E+00 0.00E+00 - - - 3.2079 1 230117_WJC_METTL3_WT_vs_EV_F02.20504.20504.2 7.13E-06 18-Nov -.MFLYNLTLQR.A "sp|Q15393|SF3B3_HUMAN,tr|H3BMB0|H3BMB0_HUMAN,tr|I3L4G7|I3L4G7_HUMAN" 3 1297.6853 0.09 16371 20504 2 1297.687735 649.8499 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.5 3798.5 - 1.55E+06 - - - 1.8934 - 2.282 0.495 - 429.9 1 2 0 0.0025 10 0 0 0 1.02E+07 1.15E+08 - - - 4.9993 1 230117_WJC_METTL3_WT_vs_EV_F02.20506.20506.3 4.06E-09 17/44 K.TVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1309.6952 0.65 16373 20506 3 1309.69567 437.5723 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3798.8 - 1.00E+06 - - - 0.378 - 3.09 0.58 - 544.8 1 2 0 0.0005 12 0 0 0 8.68E+06 1.34E+07 - - - 8.1334 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20507.20507.2 1.05E-05 16-Sep K.LLYTFPGWK.V "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1123.6066 1.61 16374 20507 2 1123.608122 562.8106 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 8.59 3798.9 - 994563 - - - 1.3394 - 1.946 0.483 - 241.3 1 2 0 0.0015 9 0 0 0 1.09E+07 6.74E+06 - - - 4.5341 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20508.20508.2 0.00238 16-Aug K.LLYTFPGWK[136.11].V "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1131.6208 1.61 16375 20508 2 1131.621039 566.8177 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 8.59 3799 - 923582 - - - 0.1962 - 1.755 0.351 - 143.1 1 2 0 0.0002 9 0 0 0 1.09E+07 6.74E+06 - - - 3.2607 1 230117_WJC_METTL3_WT_vs_EV_F02.20510.20510.2 2.09E-08 14/28 K.GVYPDLLATSGDYLR.V sp|P61962|DCAF7_HUMAN 1 1638.8253 2.23 16377 20510 2 1638.826308 820.4199 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3799.2 - 857669 - - - 0.5925 - 2.735 0.604 - 446.7 1 2 0 0.001 15 0 0 0 6.47E+06 2.90E+06 - - - 5.9755 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20515.20515.2 0.013 22-Nov R.VALDMTTLTIMR[166.11].Y "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 4 1373.7286 1.04 16382 20515 2 1373.728726 687.8716 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.81 3799.9 - 602989 - - - 0.0823 - 2.18 0.322 - 403 1 2 0 0.0001 12 0 0 0 6.64E+06 6.38E+06 - - - 3.4698 0.9536 230117_WJC_METTL3_WT_vs_EV_F02.20524.20524.2 3.36E-06 13/22 K.GAVEALAAALAH.L sp|Q9NR30|DDX21_HUMAN 1 1092.5928 - 16389 20524 2 1092.591882 547.3037 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.24 3801 - 220661 - - - -0.8018 - 2.685 0.392 - 667.8 1 1 0 -0.0009 12 0 0 0 - - - - - 4.5348 1 230117_WJC_METTL3_WT_vs_EV_F02.20527.20527.2 4.24E-09 15/26 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.47 16392 20527 2 1487.775522 744.8959 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3801.2 - 525672 - - - -1.1715 - 2.744 0.556 - 733.8 1 2 0 -0.0017 14 0 0 0 3.36E+07 2.29E+07 - - - 5.6801 1 230117_WJC_METTL3_WT_vs_EV_F02.20528.20528.2 0.000704 18-Nov K.VLEAELLVLR[166.11].Q sp|P07196|NFL_HUMAN 1 1163.7153 0.82 16393 20528 2 1163.715073 582.8649 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.53 3801.2 - 106736 - - - -0.2208 - 2.255 0.446 - 425 1 2 0 -0.0003 10 0 0 0 9.94E+06 1.21E+07 - - - 4.6048 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.20530.20530.2 0.000287 20-Oct K.GIFNGFSVTLK[136.11].E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1189.6587 1.13 16395 20530 2 1189.663375 595.8366 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3801.4 - 0 - - - 3.9642 - 2.066 0.369 - 224.6 1 2 0 0.0047 11 0 0 0 1.53E+07 1.36E+07 - - - 3.7279 1 230117_WJC_METTL3_WT_vs_EV_F02.20532.20532.2 2.25E-07 22-Dec K.FLETVELQISLK[136.11].N sp|P62906|RL10A_HUMAN 1 1426.8163 1.06 16397 20532 2 1426.818621 714.4154 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.53 3801.6 - 0 - - - 1.6393 - 2.463 0.554 - 372.2 1 2 0 0.0023 12 0 0 0 4.64E+06 4.38E+06 - - - 5.5038 1 230117_WJC_METTL3_WT_vs_EV_F02.20540.20540.2 6.52E-10 15/26 R.YSALFLGVAYGATR[166.11].Y sp|P56385|ATP5I_HUMAN 1 1497.7855 1.47 16403 20540 2 1497.785745 749.9 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3802.6 - 1.93E+06 - - - 0.1402 - 2.823 0.664 - 665.2 1 2 0 0.0002 14 0 0 0 3.36E+07 2.29E+07 - - - 6.5495 1 230117_WJC_METTL3_WT_vs_EV_F02.20541.20541.2 1.27E-05 20-Dec K.GIFNGFSVTLK.E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1181.6445 1.13 16404 20541 2 1181.643471 591.8295 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3802.7 - 1.10E+06 - - - -0.8361 - 2.342 0.447 - 375.2 1 2 0 -0.001 11 0 0 0 1.53E+07 1.36E+07 - - - 4.6444 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.20542.20542.3 9.55E-06 15/52 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.55 16405 20542 3 1487.775982 496.933 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3802.8 - 734166 - - - -0.8624 - 2.001 0.466 - 154 1 2 0 -0.0013 14 0 0 0 5.46E+06 3.54E+06 - - - 5.5785 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.20544.20544.2 0.00485 12-Aug R.WQFLTLR.E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 962.5338 1.27 16407 20544 2 962.533775 482.2742 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 9.75 3803.1 - 542986 - - - -0.0125 - 1.529 0.371 - 296 1 2 0 0 7 0 0 0 7.45E+06 5.87E+06 - - - 3.1266 1 230117_WJC_METTL3_WT_vs_EV_F02.20545.20545.2 0.000348 20-Dec K.FMELLEPLNER.K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1389.6962 -1 16408 20545 2 1389.692648 695.8554 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.25 3803.2 - 428512 - - - -2.5826 - 2.46 0.469 - 667.8 1 2 0 -0.0036 11 0 0 0 0.00E+00 0.00E+00 - - - 4.9391 0.9945 230117_WJC_METTL3_WT_vs_EV_F02.20546.20546.2 0.00493 12-Aug R.WQFLTLR[166.11].E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 972.5421 1.27 16409 20546 2 972.538476 487.2783 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 9.75 3803.3 - 403189 - - - -3.6821 - 1.712 0.398 - 295.8 1 2 0 -0.0036 7 0 0 0 7.45E+06 5.87E+06 - - - 3.6831 0.999 230117_WJC_METTL3_WT_vs_EV_F02.20547.20547.2 3.98 20-Dec K.FMELLEPLNER[166.11].K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1399.7045 0.81 16410 20547 2 1399.703175 700.8595 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.25 3803.5 - 383321 - - - -0.9516 - 1.825 0.4 - 243.2 1 2 0 -0.0013 11 0 0 0 4.15E+06 5.12E+06 - - - 3.6224 1 230117_WJC_METTL3_WT_vs_EV_F02.20553.20553.2 0.00042 20-Dec R.LLGAALPLLTK[136.11].E "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1116.7362 0.85 16416 20553 2 1116.734927 559.3754 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 8.75 3804.3 - 231642 - - - -1.1238 - 2.443 0.438 - 273.2 1 2 0 -0.0013 11 0 0 0 4.10E+06 4.83E+06 - - - 4.6921 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.20558.20558.2 0.0644 14-Sep R.VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 891.6145 1.37 16421 20558 2 891.614 446.8145 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3804.9 - 178765 - - - -0.5529 - 1.942 0.229 - 362.2 1 2 0 -0.0005 8 0 0 0 1.64E+07 1.20E+07 - - - 2.734 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.20559.20559.2 0.0677 22-Sep K.FLETVELQISLK.N sp|P62906|RL10A_HUMAN 1 1418.8021 1.05 16422 20559 2 1418.802379 710.4083 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.53 3805 - 166545 - - - 0.2093 - 1.438 0.223 - 83.5 1 2 0 0.0003 12 0 0 0 4.64E+06 4.43E+06 - - - 1.6438 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.20563.20563.2 0.114 14-Aug R.VLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 881.6062 1.37 16425 20563 2 881.606171 441.8104 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3805.4 - 4.12E+06 - - - -0.059 - 1.78 0.321 - 224.6 1 2 0 -0.0001 8 0 0 0 1.64E+07 1.20E+07 - - - 3.1509 1 230117_WJC_METTL3_WT_vs_EV_F02.20564.20564.2 0.000156 13/24 R.GAVGALLVYDIAK[136.11].H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1296.7533 1.41 16426 20564 2 1296.753636 649.3839 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3805.4 - 2.74E+06 - - - 0.2684 - 2.948 0.498 - 846.1 1 2 0 0.0003 13 0 0 0 2.08E+07 1.48E+07 - - - 5.4939 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.20569.20569.2 0.00122 16-Aug K.C[160.03]MPTFQFFK.K sp|P10599|THIO_HUMAN 1 1204.5409 3.02 16431 20569 2 1204.540913 603.2777 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3805.8 - 1.06E+06 - - - -0.0083 - 1.403 0.414 - 136.5 1 2 0 0 9 0 0 0 3.40E+07 1.12E+07 - - - 3.0784 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20573.20573.2 0.0207 16-Sep K.DLSDFPLIK.K "sp|P20585|MSH3_HUMAN,tr|A0A590UJN8|A0A590UJN8_HUMAN,tr|A0A590UKC9|A0A590UKC9_HUMAN,tr|A0A590UJW0|A0A590UJW0_HUMAN" 4 1046.5648 2.74 16435 20573 2 1046.565749 524.2897 DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4 4.21 3806.3 - 581174 - - - 0.8953 - 1.656 0.355 - 205.7 1 2 0 0.0009 9 0 0 0 2.37E+06 8.64E+05 - - - 3.122 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.20576.20576.2 0.0497 16-Aug R.LVFGFLNGR.A "sp|P00491|PNPH_HUMAN,tr|G3V2H3|G3V2H3_HUMAN,tr|G3V5M2|G3V5M2_HUMAN" 3 1021.5709 2.21 16438 20576 2 1021.574365 511.7927 Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2 9.75 3806.7 - 285832 - - - 3.3909 - 1.349 0.385 - 194.3 1 2 0 0.0035 9 0 0 0 3.29E+06 1.49E+06 - - - 2.7496 1 230117_WJC_METTL3_WT_vs_EV_F02.20577.20577.2 1.47E-06 24-Nov K.MLVLDEADEMLNK[136.11].G "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1527.7404 0.001 16439 20577 2 1527.739633 764.8775 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 3.92 3806.8 - 244165 - - - -0.5132 - 2.399 0.541 - 320 1 2 0 -0.0008 13 0 0 0 0.00E+00 1.46E+06 - - - 5.2824 0.9963 230117_WJC_METTL3_WT_vs_EV_F02.20585.20585.2 0.0124 16-Aug R.FTGLESIFR[166.11].A sp|Q8N4Q0|PTGR3_HUMAN 1 1078.5687 0.84 16445 20585 2 1078.566399 540.2916 Prostaglandin reductase 3 OS=Homo sapiens OX=9606 GN=ZADH2 PE=1 SV=1 6 3807.8 - 736924 - - - -2.1009 - 1.56 0.34 - 163.3 1 2 0 -0.0023 9 0 0 0 2.64E+07 3.15E+07 - - - 2.838 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20586.20586.2 5.27E-05 16-Aug K.C[160.03]MPTFQFFK[136.11].K sp|P10599|THIO_HUMAN 1 1212.5551 3.02 16446 20586 2 1212.557071 607.2848 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3807.9 - 1.28E+06 - - - 1.6065 - 1.281 0.512 - 140.9 1 2 0 0.0019 9 0 0 0 3.40E+07 1.12E+07 - - - 3.5385 1 230117_WJC_METTL3_WT_vs_EV_F02.20588.20588.2 4.52E-09 17/28 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.45 16448 20588 2 1548.927029 775.4692 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3808.2 - 499803 - - - 2.0014 - 3.558 0.594 - 651.1 1 2 0 0.0031 15 0 0 0 1.12E+08 7.75E+07 - - - 6.5477 1 230117_WJC_METTL3_WT_vs_EV_F02.20590.20590.2 1.95E-06 18/28 K.LLGASELPIVTPALR[166.11].A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1558.9322 1.44 16450 20590 2 1558.936041 780.4734 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3808.5 - 363694 - - - 2.4645 - 3.403 0.55 - 669.3 1 2 0 0.0038 15 0 0 0 1.12E+08 7.75E+07 - - - 6.113 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20592.20592.2 0.0048 18-Oct K.DLIGVQNLLK[136.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1119.6743 0.73 16452 20592 2 1119.675919 560.8444 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3808.7 - 345400 - - - 1.437 - 1.951 0.43 - 278.8 1 2 0 0.0016 10 0 0 0 3.02E+06 4.14E+06 - - - 4.082 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20593.20593.2 0.00564 18-Oct R.IYLDMLNVYK[136.11].C "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 11 1278.6773 5.89 16453 20593 2 1278.677993 640.3459 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.83 3808.8 - 323193 - - - 0.506 - 1.865 0.416 - 274.2 1 2 0 0.0006 10 0 0 0 1.68E+07 2.85E+06 - - - 3.8531 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20594.20594.2 0.00149 18-Oct K.DLIGVQNLLK.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1111.6601 0.67 16454 20594 2 1111.662922 556.8373 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3809 - 316202 - - - 2.5296 - 2.031 0.374 - 265.6 1 2 0 0.0028 10 0 0 0 2.79E+06 4.14E+06 - - - 3.7802 0.999 230117_WJC_METTL3_WT_vs_EV_F02.20595.20595.2 0.00129 18-Sep K.DSPFGLSFVR.F "sp|P18887|XRCC1_HUMAN,tr|M0R1U8|M0R1U8_HUMAN,tr|M0R0D2|M0R0D2_HUMAN,tr|M0QYS5|M0QYS5_HUMAN,tr|F5H8D7|F5H8D7_HUMAN,tr|M0QZ96|M0QZ96_HUMAN" 6 1123.5662 0.92 16455 20595 2 1123.568626 562.7904 DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2 5.84 3809.1 - 214420 - - - 2.1512 - 1.44 0.333 - 225.9 1 2 0 0.0024 10 0 0 0 1.60E+06 1.74E+06 - - - 2.5176 0.9883 230117_WJC_METTL3_WT_vs_EV_F02.20605.20605.2 0.00497 16-Aug R.FVC[160.03]PVILFK[136.11].G "sp|Q8NCE2|MTMRE_HUMAN,tr|B4DJ23|B4DJ23_HUMAN" 2 1129.6449 1.46 16464 20605 2 1129.64153 565.8297 Myotubularin-related protein 14 OS=Homo sapiens OX=9606 GN=MTMR14 PE=1 SV=2 8.22 3810.4 - 362167 - - - -3.0045 - 1.46 0.277 - 183.3 1 2 0 -0.0034 9 0 0 0 1.46E+07 9.97E+06 - - - 2.1807 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.20606.20606.2 0.0358 18-Jul R.LWNETVELFR[166.11].A sp|Q8WUY9|DEP1B_HUMAN 1 1315.68 -1 16465 20606 2 1315.680036 658.8473 DEP domain-containing protein 1B OS=Homo sapiens OX=9606 GN=DEPDC1B PE=1 SV=2 4.53 3810.5 - 0 - - - 0.022 - 1.409 0.237 - 172.2 1 2 0 0 10 0 0 0 0.00E+00 0.00E+00 - - - 1.7486 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20607.20607.2 0.000163 22-Jul K.IGLIQFC[160.03]LSAPK.T sp|P50991|TCPD_HUMAN 1 1345.7428 10.35 16466 20607 2 1345.745311 673.8787 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3810.5 - 1.43E+06 - - - 1.8703 - 1.801 0.376 - 156.1 1 2 0 0.0025 12 0 0 0 7.36E+07 7.11E+06 - - - 3.3654 0.9934 230117_WJC_METTL3_WT_vs_EV_F02.20608.20608.2 0.0012 18-Sep K.IMLPWDPTGK.L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1156.5951 1.76 16467 20608 2 1156.590282 579.3048 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3810.6 - 609991 - - - -4.1363 - 1.658 0.462 - 312.3 1 2 0 -0.0048 10 0 0 0 8.70E+07 4.95E+07 - - - 3.8631 1 230117_WJC_METTL3_WT_vs_EV_F02.20609.20609.2 3.29E-12 15/30 R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 11.23 16468 20609 2 1756.915594 879.4608 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3810.6 - 544250 - - - 4.9155 - 3.459 0.604 - 845.5 1 2 0 0.0086 16 0 0 0 3.05E+07 2.72E+06 - - - 6.5504 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20611.20611.2 0.000263 18-Oct K.IMLPWDPTGK[136.11].L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1164.6093 1.75 16470 20611 2 1164.61264 583.3119 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3810.8 - 345275 - - - 2.8971 - 1.7 0.443 - 348.3 1 2 0 0.0034 10 0 0 0 8.69E+07 4.95E+07 - - - 3.7931 1 230117_WJC_METTL3_WT_vs_EV_F02.20612.20612.2 0.000232 13/22 R.VIQELLVDYYVK.L "sp|Q9H6D7|HAUS4_HUMAN,tr|H0YJ09|H0YJ09_HUMAN,tr|G3V4X7|G3V4X7_HUMAN,tr|G3V5A5|G3V5A5_HUMAN,tr|G3V541|G3V541_HUMAN,tr|H0YIZ6|H0YIZ6_HUMAN,tr|G3V5Z2|G3V5Z2_HUMAN" 7 1480.8177 -1 16471 20612 2 1480.810394 741.4161 HAUS augmin-like complex subunit 4 OS=Homo sapiens OX=9606 GN=HAUS4 PE=1 SV=1 4.37 3810.9 - 0 - - - -4.956 - 2.226 0.469 - 623.5 1 2 0 -0.0073 12 0 0 0 0.00E+00 0.00E+00 - - - 4.6082 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20615.20615.2 0.00237 14-Aug K.AWGILTFK[136.11].G "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 942.5418 1.22 16473 20615 2 942.542787 472.2782 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 8.8 3811.1 - 3.27E+06 - - - 1.0058 - 1.507 0.396 - 263.5 1 2 0 0.0009 8 0 0 0 6.08E+07 4.97E+07 - - - 3.2025 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20619.20619.2 1.47E-05 20-Sep K.YFFFDDGNGLK.G sp|P61009|SPCS3_HUMAN 1 1321.5979 0.99 16477 20619 2 1321.598238 661.8062 Signal peptidase complex subunit 3 OS=Homo sapiens OX=9606 GN=SPCS3 PE=1 SV=1 4.21 3811.6 - 494753 - - - 0.2535 - 1.582 0.563 - 217.8 1 2 0 0.0003 11 0 0 0 4.21E+06 4.27E+06 - - - 4.4401 0.9173 230117_WJC_METTL3_WT_vs_EV_F02.20621.20621.2 0.00152 14-Aug R.PFSVDFFR.K "sp|Q9NYH9|UTP6_HUMAN,tr|J3QSA7|J3QSA7_HUMAN,tr|J3KRR8|J3KRR8_HUMAN" 3 1013.4971 1.31 16479 20621 2 1013.496544 507.7558 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 6.27 3811.8 - 304709 - - - -0.516 - 1.588 0.354 - 229.5 1 1 0 -0.0005 8 0 0 0 2.32E+06 1.77E+06 - - - 3.0503 0.9905 230117_WJC_METTL3_WT_vs_EV_F02.20622.20622.2 0.0152 18-Aug R.IYLDMLNVYK.C "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 11 1270.6631 1.48 16480 20622 2 1270.659398 636.3388 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.83 3812 - 287089 - - - -2.9496 - 1.64 0.262 - 170.2 1 2 0 -0.0037 10 0 0 0 3.22E+06 2.17E+06 - - - 2.3558 1 230117_WJC_METTL3_WT_vs_EV_F02.20624.20624.2 0.000285 14/22 K.IGLIQFC[160.03]LSAPK[136.11].T sp|P50991|TCPD_HUMAN 1 1353.757 10.35 16482 20624 2 1353.75515 677.8858 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3812.2 - 211828 - - - -1.3621 - 2.736 0.458 - 785.3 1 2 0 -0.0018 12 0 0 0 7.36E+07 7.11E+06 - - - 5.0715 0.9957 230117_WJC_METTL3_WT_vs_EV_F02.20629.20629.2 0.668 12-Jun K.DLVEWLK[136.11].L "sp|Q9P2D1|CHD7_HUMAN,sp|Q14554|PDIA5_HUMAN" 2 909.5051 1.82 16487 20629 2 909.506368 455.7598 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.37 3812.9 - 131765 - - - 1.3733 - 1.217 0.194 - 143.5 1 2 0 0.0012 7 0 0 0 3.53E+06 1.95E+06 - - - 1.0958 1 230117_WJC_METTL3_WT_vs_EV_F02.20635.20635.2 2.11E-06 22-Oct K.GIDPFSLDALSK.E sp|P40227|TCPZ_HUMAN 1 1261.6554 9.72 16492 20635 2 1261.653858 631.835 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3813.4 - 1.13E+07 - - - -1.2365 - 2.079 0.607 - 315 1 2 0 -0.0016 12 0 0 0 5.74E+08 5.90E+07 - - - 5.4495 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.20636.20636.2 0.00635 18-Jun R.AFDLFNPNFK.S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1211.5975 1.5 16493 20636 2 1211.596298 606.806 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3813.5 - 7.51E+06 - - - -0.9995 - 1.413 0.426 - 94 1 2 0 -0.0012 10 0 0 0 2.99E+07 1.99E+07 - - - 3.1521 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.20637.20637.3 0.000692 Aug-60 R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 18.99 16494 20637 3 1756.906076 586.6429 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3813.5 - 7.32E+06 - - - -0.502 - 1.975 0.45 - 105.6 1 2 0 -0.0009 16 0 0 0 2.69E+07 1.41E+06 - - - 5.3031 1 230117_WJC_METTL3_WT_vs_EV_F02.20638.20638.2 6.48E-07 18-Aug R.AFDLFNPNFK[136.11].S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1219.6117 1.5 16495 20638 2 1219.611243 610.8131 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3813.6 - 5.14E+06 - - - -0.3821 - 1.892 0.583 - 189.1 1 2 0 -0.0005 10 0 0 0 2.99E+07 1.99E+07 - - - 5.1267 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.20640.20640.2 0.0699 22-Aug R.VPFLVLEC[160.03]PNLK.L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1427.7847 1.25 16497 20640 2 1427.783916 714.8996 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3813.6 - 3.29E+06 - - - -0.5197 - 1.732 0.349 - 253.9 1 2 0 -0.0007 12 0 0 0 1.53E+07 1.23E+07 - - - 3.0637 0.9965 230117_WJC_METTL3_WT_vs_EV_F02.20641.20641.2 0.291 12-Jul R.EIALWFR[166.11].A "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 943.5155 1.17 16498 20641 2 943.513423 472.765 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6.1 3813.7 - 3.10E+06 - - - -2.2098 - 1.528 0.354 - 250.5 1 2 0 -0.0021 7 0 0 0 1.64E+07 1.40E+07 - - - 2.9983 1 230117_WJC_METTL3_WT_vs_EV_F02.20643.20643.2 9.78E-06 22-Oct R.VPFLVLEC[160.03]PNLK[136.11].L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1435.7989 1.25 16500 20643 2 1435.79675 718.9067 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3813.8 - 2.47E+06 - - - -1.4682 - 2.223 0.531 - 426.4 1 2 0 -0.0021 12 0 0 0 1.53E+07 1.23E+07 - - - 5.0642 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.20644.20644.2 0.000774 18-Oct R.ISYSLFTALR[166.11].V "sp|Q53GQ0|DHB12_HUMAN,tr|E9PI21|E9PI21_HUMAN,tr|A0A1B0GW85|A0A1B0GW85_HUMAN,tr|A0A1B0GU83|A0A1B0GU83_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN" 5 1179.6527 1.46 16501 20644 2 1179.650326 590.8336 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 8.75 3813.8 - 2.43E+06 - - - -2.037 - 1.996 0.456 - 298.7 1 2 0 -0.0024 10 0 0 0 6.06E+06 4.16E+06 - - - 4.3375 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20645.20645.2 0.00022 20-Jul K.WYLENVYPELR.V sp|Q10471|GALT2_HUMAN 1 1480.7351 1.01 16502 20645 2 1480.734666 741.3748 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3813.9 - 1.81E+06 - - - -0.2695 - 1.616 0.463 - 181.5 1 2 0 -0.0004 11 0 0 0 4.60E+07 4.54E+07 - - - 3.759 1 230117_WJC_METTL3_WT_vs_EV_F02.20647.20647.3 3.07E-07 13/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 2397.82 16503 20647 3 1603.762811 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3814.1 - 1.02E+07 - - - -0.704 - 2.333 0.62 - 256.6 1 2 0 -0.0011 12 0 0 0 4.07E+08 1.70E+05 - - - 7.8003 0.9596 230117_WJC_METTL3_WT_vs_EV_F02.20650.20650.2 0.000551 18-Oct L.C[160.03]FVYPLDFAR[166.11].T "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 4 1296.62 1.19 16505 20650 2 1296.620034 649.3173 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 5.83 3814.4 - 660427 - - - -0.0116 - 1.805 0.416 - 351.4 1 1 0 0 10 0 0 0 6.29E+06 5.28E+06 - - - 3.762 1 230117_WJC_METTL3_WT_vs_EV_F02.20651.20651.3 6.04E-07 20/56 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.29 16506 20651 3 1548.924621 517.3153 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3814.6 - 1.13E+06 - - - 0.4468 - 3.483 0.566 - 661.1 1 2 0 0.0007 15 0 0 0 9.73E+06 7.56E+06 - - - 8.1064 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.20652.20652.2 0.00989 18-Oct K.ILDVLEEIPK[136.11].N "sp|Q16718|NDUA5_HUMAN,tr|C9IZN5|C9IZN5_HUMAN,tr|H7BYD0|H7BYD0_HUMAN,tr|A0A087X1G1|A0A087X1G1_HUMAN,tr|F8WAS3|F8WAS3_HUMAN,tr|A0A7I2V2W4|A0A7I2V2W4_HUMAN,tr|A0A7I2V3L8|A0A7I2V3L8_HUMAN" 7 1175.6893 2.28 16507 20652 2 1175.687564 588.8519 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3 4.14 3814.7 - 788437 - - - -1.4689 - 2.053 0.27 - 178.1 1 2 0 -0.0017 10 0 0 0 6.20E+07 2.72E+07 - - - 3.0425 1 230117_WJC_METTL3_WT_vs_EV_F02.20653.20653.3 4.69E-07 20/56 K.LLGASELPIVTPALR[166.11].A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1558.9322 1.34 16508 20653 3 1558.932913 520.6513 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3814.8 - 781258 - - - 0.458 - 3.166 0.606 - 696.6 1 2 0 0.0007 15 0 0 0 9.63E+06 7.16E+06 - - - 8.3033 1 230117_WJC_METTL3_WT_vs_EV_F02.20654.20654.2 5.98E-05 13/22 K.GIDPFSLDALSK[136.11].E sp|P40227|TCPZ_HUMAN 1 1269.6696 9.65 16509 20654 2 1269.668948 635.8421 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3815 - 688957 - - - -0.5277 - 2.557 0.532 - 500.9 1 2 0 -0.0007 12 0 0 0 5.73E+08 5.94E+07 - - - 5.4404 0.9937 230117_WJC_METTL3_WT_vs_EV_F02.20657.20657.2 0.127 18-Oct K.QLLLIAGLTR.E "sp|Q9UJX2|CDC23_HUMAN,tr|D6RCF8|D6RCF8_HUMAN,tr|D6RBY8|D6RBY8_HUMAN,tr|H0Y936|H0Y936_HUMAN" 4 1096.6968 1.09 16512 20657 2 1096.694953 549.3557 Cell division cycle protein 23 homolog OS=Homo sapiens OX=9606 GN=CDC23 PE=1 SV=3 9.75 3815.4 - 402304 - - - -1.7106 - 2.174 0.106 - 301.5 1 2 0 -0.0019 10 0 0 0 3.64E+06 3.33E+06 - - - 1.991 0.988 230117_WJC_METTL3_WT_vs_EV_F02.20659.20659.2 1.06 14-May K.LFGLPNDS.- "sp|Q96J01|THOC3_HUMAN,tr|D6REC9|D6REC9_HUMAN" 2 861.4232 - 16514 20659 2 861.423614 431.7189 THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1 3.8 3815.6 - 256692 - - - 0.4423 - 0.956 0.212 - 61.1 1 2 0 0.0004 8 0 0 0 - - - - - 0.471 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.20665.20665.2 0.123 14-Jul R.ETILNLLR[166.11].K "sp|Q6P158|DHX57_HUMAN,tr|A0A087WZ11|A0A087WZ11_HUMAN" 2 980.5894 0.84 16520 20665 2 980.588874 491.302 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 6.1 3816.4 - 150961 - - - -0.5374 - 1.764 0.281 - 178.3 1 2 0 -0.0005 8 0 0 0 4.59E+06 5.46E+06 - - - 2.8281 0.9948 230117_WJC_METTL3_WT_vs_EV_F02.20666.20666.2 0.331 14-Aug R.ETILNLLR.K "sp|Q6P158|DHX57_HUMAN,tr|A0A087WZ11|A0A087WZ11_HUMAN" 2 970.5811 0.84 16521 20666 2 970.578828 486.2978 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 6.1 3816.5 - 124341 - - - -2.3728 - 1.813 0.244 - 224.4 1 2 0 -0.0023 8 0 0 0 4.59E+06 5.46E+06 - - - 2.6369 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20672.20672.2 0.0206 14-Sep K.FGFYEVFK.V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1035.5066 1.02 16526 20672 2 1035.507639 518.7606 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3817.3 - 4.45E+06 - - - 1.0333 - 1.745 0.382 - 181.4 1 2 0 0.0011 8 0 0 0 4.87E+07 4.75E+07 - - - 3.5413 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20673.20673.2 0.00031 14-Aug K.FGFYEVFK[136.11].V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1043.5208 1.02 16527 20673 2 1043.521042 522.7677 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3817.3 - 4.32E+06 - - - 0.2616 - 1.638 0.493 - 134.1 1 2 0 0.0003 8 0 0 0 4.87E+07 4.75E+07 - - - 4.1705 0.9977 230117_WJC_METTL3_WT_vs_EV_F02.20674.20674.2 0.0525 12-Jun R.EIALWFR.A "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 933.5072 1.18 16528 20674 2 933.507163 467.7609 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6.1 3817.4 - 3.49E+06 - - - -0.0803 - 1.278 0.294 - 198.5 1 2 0 -0.0001 7 0 0 0 1.65E+07 1.40E+07 - - - 1.9897 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20676.20676.2 0.0568 16-Oct K.TEILPPFFK[136.11].H sp|O75533|SF3B1_HUMAN 1 1098.6205 0.99 16530 20676 2 1098.621091 550.3175 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.66 3817.5 - 2.27E+06 - - - 0.5534 - 1.903 0.353 - 426.8 1 2 0 0.0006 9 0 0 0 7.54E+07 7.62E+07 - - - 3.5095 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20678.20678.2 0.0266 18-Aug K.FSDFLLDPYK[136.11].Y sp|Q9UIG0|BAZ1B_HUMAN 1 1251.6267 1.12 16532 20678 2 1251.627899 626.8206 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 4.21 3817.6 - 1.17E+06 - - - 0.9651 - 1.852 0.394 - 162.9 1 2 0 0.0012 10 0 0 0 1.58E+07 1.41E+07 - - - 3.6709 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20679.20679.2 0.000114 20-Sep K.FLFVDADQIVR.T sp|Q9NYU2|UGGG1_HUMAN 1 1321.703 8.81 16533 20679 2 1321.702946 661.8588 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.21 3817.6 - 1.08E+06 - - - -0.0689 - 1.969 0.47 - 227.3 1 2 0 -0.0001 11 0 0 0 6.67E+07 7.57E+06 - - - 4.3453 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20680.20680.2 0.000589 20-Oct K.ILLTQENPFFR.K sp|Q08J23|NSUN2_HUMAN 1 1376.7452 2.09 16534 20680 2 1376.747289 689.3799 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3817.7 - 1.05E+06 - - - 1.4912 - 1.917 0.485 - 389 1 2 0 0.0021 11 0 0 0 1.07E+08 5.12E+07 - - - 4.383 1 230117_WJC_METTL3_WT_vs_EV_F02.20683.20683.2 0.000271 16-Sep R.FYNLVLLPR[166.11].V "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1143.668 1.15 16537 20683 2 1143.667902 572.8413 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 3817.9 - 643328 - - - -0.0734 - 2.093 0.555 - 364.7 1 2 0 -0.0001 9 0 0 0 5.27E+07 4.60E+07 - - - 5.277 0.9107 230117_WJC_METTL3_WT_vs_EV_F02.20689.20689.2 6.53 18-Apr K.ILDVLEEIPK.N "sp|Q16718|NDUA5_HUMAN,tr|C9IZN5|C9IZN5_HUMAN,tr|H7BYD0|H7BYD0_HUMAN,tr|A0A087X1G1|A0A087X1G1_HUMAN,tr|F8WAS3|F8WAS3_HUMAN,tr|A0A7I2V2W4|A0A7I2V2W4_HUMAN,tr|A0A7I2V3L8|A0A7I2V3L8_HUMAN" 7 1167.6751 2.28 16541 20689 2 1167.674714 584.8448 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3 4.14 3818.4 - 1.66E+07 - - - -0.3229 - 0.774 0.142 - 40.4 1 2 0 -0.0004 10 0 0 0 6.20E+07 2.72E+07 - - - -0.6254 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20692.20692.2 0.000198 20-Sep K.IFGVTTLDIVR[166.11].A "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1242.7211 0.97 16542 20692 2 1242.721997 622.3678 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 5.84 3818.6 - 7.79E+06 - - - 0.6872 - 2.028 0.295 - 257.7 1 2 0 0.0009 11 0 0 0 3.68E+07 3.80E+07 - - - 3.1323 1 230117_WJC_METTL3_WT_vs_EV_F02.20694.20694.2 9.60E-06 16-Aug R.FYNLVLLPR.V "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1133.6597 1.16 16544 20694 2 1133.659642 567.8371 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 3818.7 - 3.89E+06 - - - -0.0653 - 1.813 0.524 - 266.4 1 2 0 -0.0001 9 0 0 0 5.35E+07 4.60E+07 - - - 4.6326 1 230117_WJC_METTL3_WT_vs_EV_F02.20695.20695.2 2.60E-07 24-Nov K.ILGVWDTAVSLGK.L sp|Q53RT3|APRV1_HUMAN 1 1357.7606 999 16545 20695 2 1357.759309 679.8876 Retroviral-like aspartic protease 1 OS=Homo sapiens OX=9606 GN=ASPRV1 PE=1 SV=1 5.84 3818.7 - 3.26E+06 - - - -0.9155 - 2.238 0.593 - 360.1 1 2 0 -0.0012 13 0 0 0 2.43E+07 0.00E+00 - - - 5.4881 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.20696.20696.2 0.0917 20-May R.NTISLLVAGLK.K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1127.6914 1.5 16546 20696 2 1127.691039 564.853 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.75 3818.7 - 2.99E+06 - - - -0.329 - 1.208 0.374 - 72.5 1 2 0 -0.0004 11 0 0 0 1.31E+07 8.75E+06 - - - 2.3144 0.999 230117_WJC_METTL3_WT_vs_EV_F02.20697.20697.2 0.00424 22-Apr R.VPDGMVGLIIGR.G "sp|Q92945|FUBP2_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 1225.6853 2.22 16547 20697 2 1225.688037 613.8499 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.81 3818.8 - 2.81E+06 - - - 2.251 - 1.051 0.47 - 71.5 1 2 0 0.0028 12 0 0 0 4.42E+07 1.99E+07 - - - 2.6424 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20698.20698.2 0.0201 20-Jun K.ILLTQENPFFR[166.11].K sp|Q08J23|NSUN2_HUMAN 1 1386.7535 2.2 16548 20698 2 1386.753969 694.384 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3818.8 - 2.24E+06 - - - 0.3339 - 1.541 0.46 - 126.5 1 2 0 0.0005 11 0 0 0 1.14E+08 5.20E+07 - - - 3.6082 1 230117_WJC_METTL3_WT_vs_EV_F02.20703.20703.2 3.87E-08 15/20 K.WYLENVYPELR[166.11].V sp|Q10471|GALT2_HUMAN 1 1490.7433 1.01 16552 20703 2 1490.742688 746.3789 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3819.3 - 2.57E+06 - - - -0.434 - 2.542 0.428 - 985 1 2 0 -0.0006 11 0 0 0 4.60E+07 4.54E+07 - - - 4.7259 1 230117_WJC_METTL3_WT_vs_EV_F02.20705.20705.2 4.11E-06 15/28 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 915.01 16553 20705 2 1658.901475 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3819.5 - 189364 - - - -4.5765 - 2.964 0.563 - 861.9 1 2 0 -0.0076 15 0 0 0 4.25E+08 4.64E+05 - - - 5.8682 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.20706.20706.3 0.0149 Sep-56 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 572.96 16554 20706 3 1658.905452 553.977 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3819.5 - 314957 - - - -2.1791 - 1.753 0.347 - 72.1 1 2 0 -0.0036 15 0 0 0 3.63E+08 6.34E+05 - - - 3.8724 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20710.20710.2 9.92E-06 22-Sep R.YGLFPANYVELR[166.11].Q sp|Q14247|SRC8_HUMAN 1 1450.7484 1.81 16558 20710 2 1450.750003 726.3815 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 6 3820 - 0 - - - 1.0905 - 1.903 0.453 - 213.7 1 2 0 0.0016 12 0 0 0 9.76E+06 5.39E+06 - - - 4.0793 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.20716.20716.2 0.0118 18-Sep K.YSDIDIILLK[136.11].G "sp|Q92973|TNPO1_HUMAN,tr|A0A7P0T9C0|A0A7P0T9C0_HUMAN,tr|A0A7P0TBF0|A0A7P0TBF0_HUMAN,tr|A0A7P0T944|A0A7P0T944_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 5 1199.6893 0.85 16562 20716 2 1199.694121 600.8519 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 4.21 3820.6 - 3.48E+06 - - - 4.026 - 1.432 0.379 - 155 1 2 0 0.0048 10 0 0 0 1.62E+07 1.90E+07 - - - 2.8411 0.8991 230117_WJC_METTL3_WT_vs_EV_F02.20717.20717.2 0.00133 20-Aug K.LTPLILK[136.11]PFGN.S "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1219.742 1.13 16563 20717 2 1219.742267 610.8783 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 8.75 3820.7 - 2.70E+06 - - - 0.223 - 1.527 0.288 - 194.2 1 1 0 0.0003 11 0 0 0 3.36E+07 2.97E+07 - - - 2.3132 1 230117_WJC_METTL3_WT_vs_EV_F02.20721.20721.2 2.69E-08 17/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 16567 20721 2 1343.612625 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3821 - 1.94E+06 - - - 0.8656 - 3.009 0.551 - 1152.3 1 1 0 0.0012 10 0 0 0 1.67E+07 0.00E+00 - - - 6.1852 1 230117_WJC_METTL3_WT_vs_EV_F02.20723.20723.2 2.26E-07 14/26 K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.09 16569 20723 2 1408.8283 705.4218 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3821.3 - 840093 - - - -0.4727 - 2.865 0.536 - 788.7 1 2 0 -0.0007 14 0 0 0 3.39E+08 3.12E+08 - - - 5.6411 1 230117_WJC_METTL3_WT_vs_EV_F02.20724.20724.2 1.98E-07 14/26 K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.09 16570 20724 2 1416.843023 709.4289 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3821.4 - 696588 - - - -0.1009 - 2.796 0.567 - 737.9 1 2 0 -0.0001 14 0 0 0 3.39E+08 3.12E+08 - - - 5.809 0.9412 230117_WJC_METTL3_WT_vs_EV_F02.20725.20725.2 0.0008 14-Jul R.IILLFDAH.K "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|C9JDQ8|C9JDQ8_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 7 940.5382 - 16571 20725 2 940.538707 471.2764 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 5.08 3821.6 - 499346 - - - 0.5359 - 1.398 0.375 - 137 1 1 0 0.0005 8 0 0 0 - - - - - 2.8211 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.20726.20726.2 0.0351 16-Aug K.VLGALLFVK.G sp|Q8IUR0|TPPC5_HUMAN 1 958.6215 3.62 16572 20726 2 958.622253 480.318 Trafficking protein particle complex subunit 5 OS=Homo sapiens OX=9606 GN=TRAPPC5 PE=1 SV=1 8.72 3821.7 - 329796 - - - 0.7448 - 1.373 0.297 - 101.3 1 2 0 0.0007 9 0 0 0 1.05E+06 2.90E+05 - - - 2.1515 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20731.20731.2 0.00329 20-Nov K.LFTAESLIGLK.N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1190.6911 2 16576 20731 2 1190.690418 596.3528 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6 3822.2 - 1.04E+07 - - - -0.5518 - 2.029 0.399 - 358 1 2 0 -0.0007 11 0 0 0 6.67E+07 3.34E+07 - - - 3.9019 1 230117_WJC_METTL3_WT_vs_EV_F02.20732.20732.2 0.000115 13/22 K.ALLVEVQLLESK.T sp|O00231|PSD11_HUMAN 1 1340.7915 2.2 16577 20732 2 1340.792177 671.403 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.53 3822.4 - 2.19E+06 - - - 0.4915 - 2.781 0.444 - 642.2 1 2 0 0.0007 12 0 0 0 1.92E+07 8.74E+06 - - - 5.0114 0.9969 230117_WJC_METTL3_WT_vs_EV_F02.20734.20734.2 0.0152 14-Aug K.DLEDLFYK[136.11].Y "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1049.5161 1.18 16579 20734 2 1049.51323 525.7653 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.03 3822.6 - 1.32E+06 - - - -2.7136 - 1.668 0.409 - 215.5 1 2 0 -0.0028 8 0 0 0 1.13E+07 9.59E+06 - - - 3.604 1 230117_WJC_METTL3_WT_vs_EV_F02.20735.20735.2 4.28E-08 Dec-34 K.ILDSFAAAPVPTTTLVLK.S sp|P18583|SON_HUMAN 1 1856.0659 1.74 16580 20735 2 1856.069086 929.0402 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3822.7 - 1.32E+06 - - - 1.7155 - 2.643 0.59 - 296.1 1 2 0 0.0032 18 0 0 0 4.41E+07 2.54E+07 - - - 5.7872 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.20736.20736.2 0.269 14-Sep K.VVVWDWVR.R "sp|Q5TAQ9|DCAF8_HUMAN,tr|V9GY54|V9GY54_HUMAN" 2 1057.5709 3.77 16581 20736 2 1057.571555 529.7927 DDB1- and CUL4-associated factor 8 OS=Homo sapiens OX=9606 GN=DCAF8 PE=1 SV=1 5.81 3822.9 - 1.30E+06 - - - 0.6184 - 1.787 0.242 - 323.9 1 2 0 0.0007 8 0 0 0 6.66E+06 1.77E+06 - - - 2.5791 1 230117_WJC_METTL3_WT_vs_EV_F02.20737.20737.2 4.79E-08 22-Dec R.YGLFPANYVELR.Q sp|Q14247|SRC8_HUMAN 1 1440.7402 1.93 16582 20737 2 1440.744052 721.3774 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 6 3823 - 1.27E+06 - - - 2.7076 - 2.393 0.527 - 483 1 2 0 0.0039 12 0 0 0 1.84E+07 9.56E+06 - - - 5.228 1 230117_WJC_METTL3_WT_vs_EV_F02.20738.20738.2 2.00E-09 19/34 K.ILDSFAAAPVPTTTLVLK[136.11].S sp|P18583|SON_HUMAN 1 1864.0801 1.74 16583 20738 2 1864.078271 933.0473 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3823.1 - 1.16E+06 - - - -0.9823 - 3.546 0.667 - 668.8 1 2 0 -0.0018 18 0 0 0 4.41E+07 2.54E+07 - - - 7.079 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20739.20739.2 0.0106 22-Dec K.ALLVEVQLLESK[136.11].T sp|O00231|PSD11_HUMAN 1 1348.8057 2.21 16584 20739 2 1348.806721 675.4101 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.53 3823.3 - 1.12E+06 - - - 0.7436 - 2.426 0.31 - 488.1 1 2 0 0.001 12 0 0 0 1.92E+07 8.70E+06 - - - 3.6622 0.997 230117_WJC_METTL3_WT_vs_EV_F02.20741.20741.2 0.707 16-Jul K.TLLEILDGK[136.11].L "sp|Q86YM7|HOME1_HUMAN,tr|Q86YM6|Q86YM6_HUMAN" 2 1008.5947 1.43 16586 20741 2 1008.596553 505.3046 Homer protein homolog 1 OS=Homo sapiens OX=9606 GN=HOMER1 PE=1 SV=2 4.37 3823.5 - 664912 - - - 1.8749 - 1.315 0.217 - 107.9 1 2 0 0.0019 9 0 0 0 2.23E+06 1.55E+06 - - - 1.4354 0.979 230117_WJC_METTL3_WT_vs_EV_F02.20742.20742.2 0.0136 30-Jun K.LPPPLSAPVAGLAALK.A sp|Q14781|CBX2_HUMAN 1 1513.9232 2.28 16587 20742 2 1513.922687 757.9689 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.75 3823.7 - 376718 - - - -0.3395 - 1.347 0.097 - 71.2 2 2 0 -0.0005 16 0 0 0 6.38E+06 2.79E+06 - - - 0.3552 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.20743.20743.3 2.75E-06 Dec-52 K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.22 16588 20743 3 1416.8411 473.2883 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3823.8 - 363602 - - - -1.4582 - 2.63 0.487 - 243.4 1 2 0 -0.0021 14 0 0 0 4.99E+07 4.09E+07 - - - 6.5388 0.999 230117_WJC_METTL3_WT_vs_EV_F02.20746.20746.2 3.70E-05 18-Sep K.MPLIGLGTWK.S "sp|P14550|AK1A1_HUMAN,sp|P15121|ALDR_HUMAN,tr|V9GYG2|V9GYG2_HUMAN,tr|E9PCX2|E9PCX2_HUMAN,tr|Q5T621|Q5T621_HUMAN,tr|V9GYP9|V9GYP9_HUMAN,tr|E9PEF9|E9PEF9_HUMAN" 7 1114.6209 0.69 16589 20746 2 1114.62012 558.3177 Aldo-keto reductase family 1 member A1 OS=Homo sapiens OX=9606 GN=AKR1A1 PE=1 SV=3 8.5 3824.2 - 326964 - - - -0.6881 - 1.88 0.35 - 241.1 1 2 0 -0.0008 10 0 0 0 1.32E+07 1.90E+07 - - - 3.3879 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.20747.20747.2 0.0138 14-Jul K.TFFLEALR[166.11].G "sp|Q9H0R4|HDHD2_HUMAN,tr|K7ER15|K7ER15_HUMAN" 2 1005.5523 1.65 16590 20747 2 1005.551191 503.7834 Haloacid dehalogenase-like hydrolase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=HDHD2 PE=1 SV=1 5.66 3824.3 - 139662 - - - -1.0899 - 1.207 0.358 - 167.1 1 2 0 -0.0011 8 0 0 0 7.24E+06 4.38E+06 - - - 2.2523 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.20749.20749.2 0.000109 14-Jul K.ETLLAMFK.Y sp|P26639|SYTC_HUMAN 1 951.5099 2.18 16592 20749 2 951.509264 476.7622 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 6.1 3824.6 - 282473 - - - -0.7104 - 1.465 0.469 - 150.3 1 2 0 -0.0007 8 0 0 0 6.48E+06 2.97E+06 - - - 3.6565 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.20750.20750.2 0.2 20-Oct K.LLLIPQGAILR.A sp|Q9ULM3|YETS2_HUMAN 1 1205.786 4.89 16593 20750 2 1205.784631 603.9003 YEATS domain-containing protein 2 OS=Homo sapiens OX=9606 GN=YEATS2 PE=1 SV=2 9.75 3824.7 - 159319 - - - -1.1179 - 2.094 0.265 - 349.4 1 2 0 -0.0013 11 0 0 0 2.06E+07 4.22E+06 - - - 2.9972 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20753.20753.2 0.000794 16-Aug R.GFAFVYFER[166.11].L sp|Q13595|TRA2A_HUMAN 1 1144.5581 0.85 16594 20753 2 1144.559565 573.2863 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3825.1 - 3.35E+06 - - - 1.2791 - 1.845 0.393 - 285.7 1 2 0 0.0015 9 0 0 0 6.77E+07 7.99E+07 - - - 3.7152 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20759.20759.2 1.42E-05 16-Sep K.VSFLLPTLR.K "sp|Q9UFC0|LRWD1_HUMAN,tr|H7C5S6|H7C5S6_HUMAN" 2 1044.6332 1.58 16598 20759 2 1044.633379 523.3239 Leucine-rich repeat and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRWD1 PE=1 SV=2 9.72 3825.8 - 2.08E+06 - - - 0.2029 - 1.603 0.504 - 258.4 1 2 0 0.0002 9 0 0 0 2.15E+07 1.35E+07 - - - 4.1286 1 230117_WJC_METTL3_WT_vs_EV_F02.20760.20760.2 7.46E-05 16-Oct R.YLTVAAIFR.G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1052.6019 3.09 16599 20760 2 1052.602117 527.3082 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3825.9 - 1.82E+06 - - - 0.2385 - 1.962 0.5 - 329.7 1 2 0 0.0003 9 0 0 0 4.26E+07 1.38E+07 - - - 4.6837 1 230117_WJC_METTL3_WT_vs_EV_F02.20761.20761.3 5.48E-05 16/52 K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.22 16600 20761 3 1408.8287 470.6169 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3826.1 - 2.11E+06 - - - -0.1888 - 3.199 0.546 - 381.6 1 2 0 -0.0003 14 0 0 0 4.99E+07 4.09E+07 - - - 7.7176 0.9752 230117_WJC_METTL3_WT_vs_EV_F02.20763.20763.2 0.394 14-Jul R.VIFGLFGK.T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 879.5218 0.61 16602 20763 2 879.520463 440.7682 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.72 3826.3 - 550901 - - - -1.5486 - 0.982 0.242 - 109.3 1 2 0 -0.0014 8 0 0 0 3.10E+07 5.05E+07 - - - 0.7732 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.20765.20765.2 0.0439 16-Aug K.TSVVGLFLR.H "sp|Q9UJX4|APC5_HUMAN,tr|F5GY68|F5GY68_HUMAN,tr|F5H0F9|F5H0F9_HUMAN,tr|F5GZ05|F5GZ05_HUMAN,tr|F5H3S5|F5H3S5_HUMAN" 5 990.5862 0.57 16604 20765 2 990.58493 496.3004 Anaphase-promoting complex subunit 5 OS=Homo sapiens OX=9606 GN=ANAPC5 PE=1 SV=2 9.41 3826.6 - 255527 - - - -1.2982 - 1.376 0.389 - 133 1 2 0 -0.0013 9 0 0 0 1.49E+06 2.62E+06 - - - 2.8372 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20769.20769.2 0.0647 16-Sep R.GFAFVYFER.L sp|Q13595|TRA2A_HUMAN 1 1134.5498 0.85 16606 20769 2 1134.550403 568.2822 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3827.1 - 1.87E+06 - - - 0.5042 - 1.896 0.401 - 415.4 1 2 0 0.0006 9 0 0 0 6.77E+07 7.99E+07 - - - 3.8534 0.9234 230117_WJC_METTL3_WT_vs_EV_F02.20774.20774.3 1.78E-05 Nov-36 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 16611 20774 3 1343.609049 448.8778 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3827.7 - 136621 - - - -1.7959 - 1.786 0.537 - 258.1 1 1 0 -0.0024 10 0 0 0 2.37E+06 0.00E+00 - - - 6.2201 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20783.20783.2 0.0172 16-Aug R.YLTVAAIFR[166.11].G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1062.6101 3.1 16618 20783 2 1062.610359 532.3123 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3828.7 - 1.33E+06 - - - 0.2099 - 1.945 0.394 - 210.7 1 2 0 0.0002 9 0 0 0 4.26E+07 1.38E+07 - - - 3.8757 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20784.20784.2 0.00017 13/30 K.LFVEALGQIGPAPPLK.V "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1648.9552 7 16619 20784 2 1648.957903 825.4849 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3828.9 - 1.11E+06 - - - 1.6216 - 1.685 0.475 - 203.8 1 2 0 0.0027 16 0 0 0 8.72E+06 1.25E+06 - - - 3.8313 1 230117_WJC_METTL3_WT_vs_EV_F02.20785.20785.2 1.10E-06 13/26 K.ELIELTEASLVSVR.K "sp|Q8N5A5|ZGPAT_HUMAN,tr|X6RGY1|X6RGY1_HUMAN" 2 1557.8614 2.86 16620 20785 2 1557.864251 779.938 Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3 4.25 3829 - 1.05E+06 - - - 1.8378 - 2.977 0.569 - 589.9 1 2 0 0.0029 14 0 0 0 6.44E+06 2.25E+06 - - - 5.9803 0.9894 230117_WJC_METTL3_WT_vs_EV_F02.20786.20786.2 0.0582 22-Oct R.YFVAELAAMNIK.V sp|Q9H9Y6|RPA2_HUMAN 1 1368.7112 8.73 16621 20786 2 1368.709306 685.3629 DNA-directed RNA polymerase I subunit RPA2 OS=Homo sapiens OX=9606 GN=POLR1B PE=1 SV=2 6 3829.1 - 688318 - - - -1.3538 - 1.736 0.115 - 215 1 2 0 -0.0019 12 0 0 0 7.39E+06 8.46E+05 - - - 1.3411 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.20789.20789.2 0.0158 14-Sep R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 999 16624 20789 2 1000.558338 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3829.5 - 436367 - - - -0.9944 - 1.988 0.284 - 283.1 1 2 0 -0.001 8 0 0 0 4.57E+06 0.00E+00 - - - 3.2107 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.20790.20790.2 0.00156 24-Aug R.ILFIGGITAPTVR.Q sp|P48651|PTSS1_HUMAN 1 1356.8129 0.87 16625 20790 2 1356.810865 679.4137 Phosphatidylserine synthase 1 OS=Homo sapiens OX=9606 GN=PTDSS1 PE=1 SV=1 9.75 3829.6 - 381345 - - - -1.5161 - 2.008 0.414 - 153 1 2 0 -0.0021 13 0 0 0 3.24E+06 3.75E+06 - - - 3.8874 0.9912 230117_WJC_METTL3_WT_vs_EV_F02.20791.20791.2 0.0169 18-Oct R.QALTDFLLAR[166.11].K "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1156.648 0.82 16626 20791 2 1156.644227 579.3313 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.84 3829.8 - 313108 - - - -3.243 - 1.938 0.238 - 186 1 2 0 -0.0038 10 0 0 0 6.99E+06 8.55E+06 - - - 2.6446 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.20797.20797.2 0.0279 16-Jul K.IELPELFDR.G "sp|Q9Y2Z4|SYYM_HUMAN,tr|H0YHS6|H0YHS6_HUMAN" 2 1130.5972 1.4 16631 20797 2 1130.597954 566.3059 "Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2" 4.14 3830.4 - 1.07E+06 - - - 0.689 - 1.767 0.164 - 166.2 1 2 0 0.0008 9 0 0 0 1.84E+07 1.32E+07 - - - 1.899 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.20803.20803.2 0.0168 18-Sep K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.59 16635 20803 2 1168.70616 585.3606 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3831.2 - 223968 - - - -0.4834 - 1.64 0.313 - 157 1 2 0 -0.0006 10 0 0 0 6.36E+06 4.01E+06 - - - 2.7335 0.9889 230117_WJC_METTL3_WT_vs_EV_F02.20807.20807.2 0.0208 14-Jul R.VIFGLFGK[136.11].T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 887.536 0.61 16637 20807 2 887.533085 444.7753 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.72 3831.7 - 6.05E+06 - - - -3.3125 - 1.375 0.329 - 141.8 1 2 0 -0.0029 8 0 0 0 3.10E+07 5.05E+07 - - - 2.4305 0.9904 230117_WJC_METTL3_WT_vs_EV_F02.20808.20808.2 0.0562 14-Oct K.LLELLWNK.Y "sp|Q92905|CSN5_HUMAN,tr|E5RHH5|E5RHH5_HUMAN" 2 1027.6066 1.18 16638 20808 2 1027.60372 514.8106 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 6 3831.8 - 305090 - - - -2.8192 - 2.028 0.148 - 291.7 1 2 0 -0.0029 8 0 0 0 7.49E+06 6.33E+06 - - - 2.2656 1 230117_WJC_METTL3_WT_vs_EV_F02.20812.20812.2 3.37E-06 20-Sep R.GGYFDEFGIIR.D "sp|P11413|G6PD_HUMAN,tr|E7EM57|E7EM57_HUMAN,tr|E7EUI8|E7EUI8_HUMAN" 3 1272.6139 4.69 16642 20812 2 1272.609585 637.3142 Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4 4.37 3832.3 - 829421 - - - -3.3812 - 1.771 0.593 - 197.2 1 2 0 -0.0043 11 0 0 0 5.74E+06 1.22E+06 - - - 4.9657 1 230117_WJC_METTL3_WT_vs_EV_F02.20830.20830.3 5.51E-09 17/60 R.TPEQVAEEEYLLQELR.K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1945.9633 -1 16658 20830 3 1945.958932 649.6617 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3834.7 - 314944 - - - -2.238 - 3.178 0.604 - 370.8 1 2 0 -0.0044 16 0 0 0 0.00E+00 0.00E+00 - - - 8.2396 1 230117_WJC_METTL3_WT_vs_EV_F02.20831.20831.3 3.36E-08 15/60 R.TPEQVAEEEYLLQELR[166.11].K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1955.9716 1.3 16659 20831 3 1955.969021 652.9978 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3834.8 - 293872 - - - -1.2965 - 2.845 0.573 - 260.2 1 2 0 -0.0025 16 0 0 0 3.89E+06 2.99E+06 - - - 7.6105 1 230117_WJC_METTL3_WT_vs_EV_F02.20832.20832.2 3.33E-08 14/26 R.VVAVFVQGPAWQFK[136.11].G "sp|Q6P1J9|CDC73_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1582.8751 1.7 16660 20832 2 1582.874953 792.4448 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.72 3835 - 235916 - - - -0.115 - 2.937 0.594 - 627.4 1 2 0 -0.0002 14 0 0 0 4.60E+06 2.70E+06 - - - 6.1319 1 230117_WJC_METTL3_WT_vs_EV_F02.20834.20834.2 1.16E-06 14/24 K.MVFINNIALAQIK[136.11].N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1481.852 1.05 16662 20834 2 1481.852071 741.9333 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3835.2 - 175012 - - - 0.0776 - 2.686 0.535 - 567.2 1 2 0 0.0001 13 0 0 0 3.65E+07 3.49E+07 - - - 5.5283 0.9866 230117_WJC_METTL3_WT_vs_EV_F02.20837.20837.2 0.000471 18-Sep K.EFVEAVLELR.K "sp|O75367|H2AY_HUMAN,tr|B4DJC3|B4DJC3_HUMAN" 2 1203.6499 0.72 16665 20837 2 1203.643442 602.8322 Core histone macro-H2A.1 OS=Homo sapiens OX=9606 GN=MACROH2A1 PE=1 SV=4 4.25 3835.6 - 111459 - - - -5.3977 - 1.857 0.44 - 289.6 1 2 0 -0.0065 10 0 0 0 1.37E+07 1.91E+07 - - - 4.0165 1 230117_WJC_METTL3_WT_vs_EV_F02.20838.20838.2 2.84E-07 Oct-32 R.FLVGPYQNTIGAAFVAK[136.11].V "sp|Q969Q5|RAB24_HUMAN,tr|D6RFW3|D6RFW3_HUMAN" 2 1802.9811 -1 16666 20838 2 1802.967555 902.4978 Ras-related protein Rab-24 OS=Homo sapiens OX=9606 GN=RAB24 PE=1 SV=1 8.59 3835.7 - 106828 - - - -7.4882 - 2.451 0.553 - 194.5 1 2 0 -0.0135 17 0 0 0 0.00E+00 0.00E+00 - - - 5.3253 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20841.20841.3 0.00196 Nov-60 K.LPPPLSAPVAGLAALK.A sp|Q14781|CBX2_HUMAN 1 1513.9232 4.41 16669 20841 3 1513.922342 505.6483 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.75 3836.1 - 74190.4 - - - -0.5674 - 1.769 0.372 - 91.2 1 2 0 -0.0009 16 0 0 0 2.97E+06 6.72E+05 - - - 4.1508 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20846.20846.2 0.00754 20-Nov K.ELGIWEPLAVK.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1253.702 10.12 16673 20846 2 1253.701169 627.8583 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3836.7 - 1.26E+07 - - - -0.6421 - 2.114 0.4 - 453.8 1 2 0 -0.0008 11 0 0 0 1.33E+09 1.31E+08 - - - 4.0202 1 230117_WJC_METTL3_WT_vs_EV_F02.20847.20847.2 1.02E-06 14/24 K.MVFINNIALAQIK.N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1473.8378 1.05 16674 20847 2 1473.837651 737.9262 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3836.8 - 7.14E+06 - - - -0.0712 - 2.584 0.626 - 579 1 2 0 -0.0001 13 0 0 0 3.65E+07 3.49E+07 - - - 6.1011 1 230117_WJC_METTL3_WT_vs_EV_F02.20850.20850.2 5.63E-06 13/24 K.VLGTAFDPFLGGK.N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1320.7078 8.62 16677 20850 2 1320.707327 661.3612 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3836.9 - 5.88E+06 - - - -0.3491 - 2.248 0.523 - 410.4 1 2 0 -0.0005 13 0 0 0 4.95E+08 5.74E+07 - - - 4.9827 1 230117_WJC_METTL3_WT_vs_EV_F02.20852.20852.2 4.73E-14 20/30 R.TPEQVAEEEYLLQELR.K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1945.9633 -1 16679 20852 2 1945.963663 973.9889 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3837.2 - 2.50E+06 - - - 0.1932 - 4.095 0.638 - 1403.9 1 2 0 0.0004 16 0 0 0 0.00E+00 0.00E+00 - - - 7.2191 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20853.20853.2 0.0185 14-Oct K.EALLELLR[166.11].L sp|Q13895|BYST_HUMAN 1 965.5785 1.18 16680 20853 2 965.578635 483.7965 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3837.3 - 1.72E+06 - - - 0.1377 - 2.126 0.362 - 379.9 2 2 0 0.0001 8 0 0 0 5.19E+07 4.41E+07 - - - 3.855 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20854.20854.2 0.00488 14-Aug K.EALLELLR.L sp|Q13895|BYST_HUMAN 1 955.5702 1.18 16681 20854 2 955.570378 478.7924 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3837.4 - 1.40E+06 - - - 0.1528 - 1.858 0.349 - 211.8 1 2 0 0.0001 8 0 0 0 5.19E+07 4.41E+07 - - - 3.4871 0.926 230117_WJC_METTL3_WT_vs_EV_F02.20856.20856.2 0.00315 22-Nov R.LYGLQEALEIAR.E "sp|Q9UGU0|TCF20_HUMAN,tr|A9JX13|A9JX13_HUMAN" 2 1374.7507 -1 16683 20856 2 1375.7541 688.3826 Transcription factor 20 OS=Homo sapiens OX=9606 GN=TCF20 PE=1 SV=3 4.53 3837.7 - 1.33E+06 - - - 729.8661 - 1.944 0.338 - 475.5 1 2 0 1.0034 12 0 0 0 0.00E+00 0.00E+00 - - - 2.9715 1 230117_WJC_METTL3_WT_vs_EV_F02.20857.20857.2 4.56E-07 30-Dec R.LIADLGSTSITNLGFR.D sp|Q92520|FAM3C_HUMAN 1 1676.9097 1.55 16684 20857 2 1676.91288 839.4621 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 5.84 3837.8 - 1.26E+06 - - - 1.8755 - 2.607 0.526 - 309.4 1 2 0 0.0031 16 0 0 0 3.39E+06 2.18E+06 - - - 5.2808 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20859.20859.2 0.0313 22-Aug R.LYGLQEALEIAR[166.11].E "sp|Q9UGU0|TCF20_HUMAN,tr|A9JX13|A9JX13_HUMAN" 2 1384.759 0.24 16686 20859 2 1384.759742 693.3868 Transcription factor 20 OS=Homo sapiens OX=9606 GN=TCF20 PE=1 SV=3 4.53 3838.1 - 893907 - - - 0.5459 - 1.62 0.364 - 125.9 1 2 0 0.0008 12 0 0 0 6.50E+06 2.68E+07 - - - 2.9986 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20860.20860.2 0.0013 22-Dec R.LALFNPDVC[160.03]WDR.N sp|O00483|NDUA4_HUMAN 1 1504.7133 2.06 16687 20860 2 1504.716994 753.3639 Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1 4.21 3838.2 - 791167 - - - 2.4656 - 2.541 0.403 - 576.5 1 2 0 0.0037 12 0 0 0 1.57E+07 7.62E+06 - - - 4.4701 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.20861.20861.3 0.295 Nov-48 K.MVFINNIALAQIK[136.11].N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1481.852 0.59 16688 20861 3 1481.849756 494.9579 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3838.3 - 531628 - - - -1.4846 - 2.08 0.348 - 224.7 1 2 0 -0.0022 13 0 0 0 1.26E+06 2.13E+06 - - - 4.4049 0.9924 230117_WJC_METTL3_WT_vs_EV_F02.20864.20864.2 0.0179 20-Sep K.ELGIWEPLAVK[136.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1261.7162 10.12 16689 20864 2 1261.712619 631.8654 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3838.7 - 471334 - - - -2.8176 - 1.663 0.284 - 286.8 1 2 0 -0.0036 11 0 0 0 1.33E+09 1.31E+08 - - - 2.5135 1 230117_WJC_METTL3_WT_vs_EV_F02.20867.20867.2 7.51E-06 15/26 K.LGLVGVNLTLDGVK.S "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 1396.829 1.33 16692 20867 2 1396.828224 699.4218 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 3839 - 0 - - - -0.5312 - 2.961 0.509 - 714.8 1 2 0 -0.0007 14 0 0 0 5.60E+07 4.22E+07 - - - 5.5243 1 230117_WJC_METTL3_WT_vs_EV_F02.20870.20870.2 1.93E-07 14/30 R.LIADLGSTSITNLGFR[166.11].D sp|Q92520|FAM3C_HUMAN 1 1686.918 -1 16695 20870 2 1686.910748 844.4663 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 5.84 3839.4 - 0 - - - -4.3019 - 2.645 0.584 - 560.9 1 2 0 -0.0073 16 0 0 0 0.00E+00 0.00E+00 - - - 5.7435 1 230117_WJC_METTL3_WT_vs_EV_F02.20871.20871.2 3.05E-06 14/30 R.IASLPVEVQEVSLLDK.L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1738.9717 2.8 16696 20871 2 1738.967102 870.4931 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.14 3839.5 - 0 - - - -2.6251 - 2.428 0.522 - 434.2 1 2 0 -0.0046 16 0 0 0 2.43E+07 8.66E+06 - - - 5.076 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.20872.20872.2 0.000373 22-Nov R.LALFNPDVC[160.03]WDR[166.11].N sp|O00483|NDUA4_HUMAN 1 1514.7216 2.03 16697 20872 2 1514.720084 758.3681 Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1 4.21 3839.6 - 0 - - - -0.9705 - 1.867 0.443 - 446.5 1 2 0 -0.0015 12 0 0 0 1.59E+07 7.82E+06 - - - 3.9553 1 230117_WJC_METTL3_WT_vs_EV_F02.20874.20874.2 6.40E-09 15/28 K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 0.72 16699 20874 2 1521.872749 761.945 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3839.9 - 0 - - - -1.7498 - 3.023 0.602 - 659.3 1 2 0 -0.0027 15 0 0 0 1.43E+07 1.97E+07 - - - 6.2063 1 230117_WJC_METTL3_WT_vs_EV_F02.20876.20876.2 7.92E-05 13/24 K.LLEQALVIEEQLR.R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1552.8825 1.48 16701 20876 2 1552.881837 777.4485 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3840 - 0 - - - -0.3999 - 2.98 0.488 - 710.7 1 2 0 -0.0006 13 0 0 0 2.08E+07 1.41E+07 - - - 5.4476 0.9927 230117_WJC_METTL3_WT_vs_EV_F02.20882.20882.3 2.33E-06 13/56 K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 0.89 16707 20882 3 1521.863549 508.2991 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3840.7 - 162120 - - - -7.795 - 2.498 0.499 - 280.9 1 2 0 -0.0119 15 0 0 0 9.07E+06 1.02E+07 - - - 6.4889 1 230117_WJC_METTL3_WT_vs_EV_F02.20885.20885.2 4.25E-06 24-Aug K.VLGTAFDPFLGGK[136.11].N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1328.722 8.62 16708 20885 2 1328.721215 665.3683 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3841.1 - 4.97E+06 - - - -0.5818 - 2.09 0.645 - 164 1 2 0 -0.0008 13 0 0 0 4.95E+08 5.74E+07 - - - 5.6967 1 230117_WJC_METTL3_WT_vs_EV_F02.20886.20886.2 1.48E-06 14/26 K.LGLVGVNLTLDGVK[136.11].S "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 1404.8432 1.33 16709 20886 2 1404.842848 703.4289 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 3841.2 - 4.04E+06 - - - -0.2264 - 3.005 0.573 - 643.5 1 2 0 -0.0003 14 0 0 0 5.60E+07 4.22E+07 - - - 6.0342 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.20887.20887.2 1.05E-05 20-Dec K.TLPLFYGSIVR[166.11].F "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1274.7262 1.38 16710 20887 2 1274.724597 638.3704 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 8.41 3841.3 - 1.98E+06 - - - -1.2803 - 2.159 0.267 - 554.2 1 2 0 -0.0016 11 0 0 0 3.51E+07 2.53E+07 - - - 3.0946 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20888.20888.2 0.0112 20-Dec K.LLPAITILGC[160.03]R.V "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 2 1225.7217 2.58 16711 20888 2 1225.722562 613.8681 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 8.25 3841.4 - 1.79E+06 - - - 0.7326 - 2.139 0.401 - 478.6 1 2 0 0.0009 11 0 0 0 2.05E+07 7.94E+06 - - - 4.0594 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.20891.20891.3 3.89E-05 14/48 K.LLEQALVIEEQLR.R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1552.8825 1.92 16714 20891 3 1552.883021 518.6348 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3841.8 - 1.24E+06 - - - 0.3626 - 2.593 0.479 - 367.1 1 2 0 0.0006 13 0 0 0 1.13E+07 5.89E+06 - - - 6.4636 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.20894.20894.2 0.00233 20-Sep R.LLLQAIQSFEK.K "sp|O14920|IKKB_HUMAN,tr|A0A499FJS7|A0A499FJS7_HUMAN" 2 1288.7391 2.16 16717 20894 2 1288.737186 645.3768 Inhibitor of nuclear factor kappa-B kinase subunit beta OS=Homo sapiens OX=9606 GN=IKBKB PE=1 SV=1 6 3842.2 - 954840 - - - -1.4759 - 1.837 0.364 - 260 1 2 0 -0.0019 11 0 0 0 1.16E+07 5.37E+06 - - - 3.3741 1 230117_WJC_METTL3_WT_vs_EV_F02.20895.20895.2 0.000109 13/24 K.ALVLANPEVSLWR.K "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 1466.8245 1.08 16718 20895 2 1466.822447 734.4196 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6.05 3842.3 - 939021 - - - -1.433 - 2.646 0.447 - 666.1 1 2 0 -0.0021 13 0 0 0 1.08E+07 1.00E+07 - - - 4.8392 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.20896.20896.3 1.21E-06 16/56 K.TVAGQDAVIVLLGTR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1511.8671 0.89 16719 20896 3 1511.866108 504.963 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3842.5 - 846770 - - - -0.6839 - 2.669 0.527 - 442.3 1 2 0 -0.001 15 0 0 0 9.09E+06 1.02E+07 - - - 6.9769 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20897.20897.2 0.00453 18-Oct K.EFLFNPYLTR[166.11].K "sp|P13378|HXD8_HUMAN,sp|P31273|HXC8_HUMAN,sp|P17481|HXB8_HUMAN,tr|I3L3R1|I3L3R1_HUMAN,tr|I3L383|I3L383_HUMAN,tr|A0A0A0MSX5|A0A0A0MSX5_HUMAN,tr|A0A0A0MTF4|A0A0A0MTF4_HUMAN" 7 1308.6742 2.16 16720 20897 2 1308.674277 655.3444 Homeobox protein Hox-D8 OS=Homo sapiens OX=9606 GN=HOXD8 PE=1 SV=2 6.1 3842.6 - 845235 - - - 0.0642 - 1.825 0.364 - 439.1 1 2 0 0.0001 10 0 0 0 1.53E+07 7.10E+06 - - - 3.4087 1 230117_WJC_METTL3_WT_vs_EV_F02.20898.20898.2 1.45E-06 17/28 K.TVAGQDAVIVLLGTR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1511.8671 0.72 16721 20898 2 1511.864758 756.9408 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3842.7 - 828671 - - - -1.5769 - 3.099 0.623 - 776.8 1 2 0 -0.0024 15 0 0 0 1.43E+07 1.97E+07 - - - 6.4225 0.9066 230117_WJC_METTL3_WT_vs_EV_F02.20901.20901.2 0.327 20-Oct K.SLPASLSFLVK.L "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN" 5 1160.6805 0.94 16724 20901 2 1160.687659 581.3475 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 8.47 3843.1 - 643599 - - - 6.1585 - 1.229 0.158 - 169 1 2 0 0.0071 11 0 0 0 6.43E+06 6.87E+06 - - - 0.7636 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.20902.20902.2 0.000471 16/24 K.LLEQALVIEEQLR[166.11].R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1562.8907 1.49 16725 20902 2 1562.889835 782.4526 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3843.3 - 623713 - - - -0.5714 - 2.765 0.373 - 1200.7 1 2 0 -0.0009 13 0 0 0 2.08E+07 1.40E+07 - - - 4.406 1 230117_WJC_METTL3_WT_vs_EV_F02.20903.20903.2 0.0401 13/26 K.NLPIYSEEIVEMYK.G "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1726.8488 1.12 16726 20903 2 1726.846914 864.4317 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3843.4 - 578711 - - - -1.0777 - 2.612 0.48 - 442.5 1 2 0 -0.0019 14 0 0 0 1.08E+07 9.63E+06 - - - 4.9951 1 230117_WJC_METTL3_WT_vs_EV_F02.20906.20906.2 3.23E-05 22-Dec R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 6186.32 16728 20906 2 1603.763487 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3843.7 - 4.71E+08 - - - -0.2825 - 2.03 0.545 - 370.9 1 2 0 -0.0005 12 0 0 0 4.93E+09 7.97E+05 - - - 4.9292 0.9608 230117_WJC_METTL3_WT_vs_EV_F02.20907.20907.2 0.00065 20-Sep D.GMVPFVFVGTK[136.11].E "sp|P51114|FXR1_HUMAN,sp|Q06787|FMR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 9 1188.6457 1 16729 20907 2 1188.645835 595.3301 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 8.75 3843.9 - 430902 - - - 0.154 - 1.71 0.43 - 177.6 1 1 0 0.0002 11 0 0 0 3.53E+06 3.55E+06 - - - 3.6683 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.20908.20908.2 0.00613 22-Nov K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 1.2 16730 20908 2 1314.791034 658.4028 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3843.9 - 1.36E+07 - - - -0.0685 - 2.13 0.466 - 384.7 1 2 0 -0.0001 12 0 0 0 6.41E+07 5.35E+07 - - - 4.4723 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20910.20910.2 0.00143 20-Dec R.QLLEEMLTSYR[166.11].L sp|O75688|PPM1B_HUMAN 1 1391.6994 0.45 16732 20910 2 1391.698938 696.857 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3844 - 1.18E+07 - - - -0.3478 - 2.352 0.429 - 648.5 1 2 0 -0.0005 11 0 0 0 1.84E+07 4.12E+07 - - - 4.5231 1 230117_WJC_METTL3_WT_vs_EV_F02.20911.20911.2 9.92E-05 20-Dec R.QLLEEMLTSYR.L sp|O75688|PPM1B_HUMAN 1 1381.6912 0.45 16733 20911 2 1381.692718 691.8529 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3844.1 - 4.91E+06 - - - 1.1334 - 2.511 0.547 - 750.8 1 2 0 0.0016 11 0 0 0 1.84E+07 4.12E+07 - - - 5.5713 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.20913.20913.3 0.000282 15/48 K.LLEQALVIEEQLR[166.11].R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1562.8907 1.92 16735 20913 3 1562.890991 521.9709 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3844.2 - 2.94E+06 - - - 0.1683 - 2.581 0.358 - 468.9 1 2 0 0.0003 13 0 0 0 1.13E+07 5.89E+06 - - - 5.1021 1 230117_WJC_METTL3_WT_vs_EV_F02.20917.20917.2 1.25E-08 13/24 R.LGSTIFVANLDFK.V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1423.7711 1.93 16739 20917 2 1423.773109 712.8928 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3844.7 - 1.32E+06 - - - 1.3991 - 3.045 0.543 - 670.4 1 2 0 0.002 13 0 0 0 1.41E+07 7.28E+06 - - - 5.9088 1 230117_WJC_METTL3_WT_vs_EV_F02.20921.20921.2 8.33E-06 14/30 R.LPC[160.03]IYLVDSGGAYLPR.Q "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJW5|A0A804HJW5_HUMAN,tr|A0A0G2JM88|A0A0G2JM88_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HIH3|A0A804HIH3_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|D6RDF7|D6RDF7_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HJW2|A0A804HJW2_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|D6R9R1|D6R9R1_HUMAN,tr|A0A804HHS4|A0A804HHS4_HUMAN,tr|A0A0S2Z5R4|A0A0S2Z5R4_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 16 1792.9182 -1 16743 20921 2 1792.920577 897.4664 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.83 3845.3 - 993158 - - - 1.3302 - 2.901 0.615 - 596.2 1 2 0 0.0024 16 0 0 0 0.00E+00 0.00E+00 - - - 6.2011 1 230117_WJC_METTL3_WT_vs_EV_F02.20922.20922.2 9.36E-06 14/24 R.LGSTIFVANLDFK[136.11].V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1431.7853 1.93 16744 20922 2 1431.785651 716.8999 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3845.4 - 989141 - - - 0.2333 - 3.118 0.534 - 826.7 1 2 0 0.0003 13 0 0 0 1.41E+07 7.28E+06 - - - 5.9037 1 230117_WJC_METTL3_WT_vs_EV_F02.20929.20929.2 0.000148 13/22 K.LVTLPVSFAQLK[136.11].N sp|Q96AG4|LRC59_HUMAN 1 1322.8053 1.2 16750 20929 2 1322.803832 662.4099 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3846.2 - 1.89E+07 - - - -1.1279 - 2.389 0.489 - 480.2 1 2 0 -0.0015 12 0 0 0 6.38E+07 5.31E+07 - - - 4.9437 1 230117_WJC_METTL3_WT_vs_EV_F02.20931.20931.2 0.000223 16-Oct R.MLYVWALC[160.03]R.D "sp|O43615|TIM44_HUMAN,tr|M0QXM9|M0QXM9_HUMAN" 2 1210.5991 1.41 16752 20931 2 1210.599834 606.3068 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 7.98 3846.4 - 1.51E+06 - - - 0.6014 - 2.107 0.493 - 497 1 2 0 0.0007 9 0 0 0 4.74E+06 3.35E+06 - - - 4.8382 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.20937.20937.3 9.58E-05 14/44 K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 1.15 16758 20937 3 1314.790543 439.271 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3847.2 - 874076 - - - -0.4419 - 2.51 0.453 - 345.7 1 2 0 -0.0006 12 0 0 0 1.75E+06 1.52E+06 - - - 6.1412 1 230117_WJC_METTL3_WT_vs_EV_F02.20938.20938.2 2.69E-07 15/26 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.94 16759 20938 2 1669.889122 835.9552 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3847.3 - 822064 - - - -4.0769 - 2.719 0.56 - 681.5 1 2 0 -0.0068 14 0 0 0 5.82E+07 6.20E+07 - - - 5.6851 1 230117_WJC_METTL3_WT_vs_EV_F02.20939.20939.2 1.27E-06 18-Nov K.GYGFVSFFNK.W "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN" 4 1164.5604 1.62 16760 20939 2 1164.557151 583.2875 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 8.59 3847.4 - 807448 - - - -2.7856 - 2.023 0.595 - 393.7 1 2 0 -0.0032 10 0 0 0 2.91E+06 1.80E+06 - - - 5.4014 1 230117_WJC_METTL3_WT_vs_EV_F02.20940.20940.3 9.85E-12 15/56 R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 1.14 16761 20940 3 2001.972769 668.3319 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3847.5 - 884222 - - - -0.4815 - 3.091 0.652 - 504.1 1 2 0 -0.001 15 0 0 0 1.89E+06 1.66E+06 - - - 8.7535 1 230117_WJC_METTL3_WT_vs_EV_F02.20941.20941.2 5.29E-05 20-Oct R.DINAVLIDMER.Q "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1287.6493 1.88 16762 20941 2 1287.63705 644.8319 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.03 3847.7 - 722467 - - - -9.5034 - 2.114 0.488 - 360 1 2 0 -0.0122 11 0 0 0 5.60E+06 2.98E+06 - - - 4.6666 0.98 230117_WJC_METTL3_WT_vs_EV_F02.20942.20942.3 0.0483 Nov-44 K.LVTLPVSFAQLK[136.11].N sp|Q96AG4|LRC59_HUMAN 1 1322.8053 1.15 16763 20942 3 1322.803844 441.9424 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3847.8 - 691334 - - - -1.1188 - 1.278 0.223 - 83.7 1 2 0 -0.0015 12 0 0 0 1.75E+06 1.52E+06 - - - 1.7057 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.20943.20943.2 0.0131 14-Sep R.QVLPFLLR.R "sp|O14981|BTAF1_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 2 984.612 -1 16764 20943 2 984.611968 493.3133 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 9.75 3847.9 - 683146 - - - -0.0701 - 1.729 0.341 - 283.8 1 2 0 -0.0001 8 0 0 0 0.00E+00 0.00E+00 - - - 3.211 0.9477 230117_WJC_METTL3_WT_vs_EV_F02.20944.20944.3 0.733 Sep-40 R.QLLEEMLTSYR[166.11].L sp|O75688|PPM1B_HUMAN 1 1391.6994 -1 16765 20944 3 1391.697648 464.9071 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3848.1 - 632669 - - - -1.2747 - 1.504 0.128 - 115.1 1 2 0 -0.0018 11 0 0 0 0.00E+00 0.00E+00 - - - 1.126 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.20945.20945.3 0.000279 Dec-44 R.EGFLDTLVVLHR.A "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 1397.7667 -1 16766 20945 3 1397.766545 466.9295 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.32 3848.2 - 568959 - - - -0.1109 - 2.35 0.38 - 149 1 2 0 -0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1449 1 230117_WJC_METTL3_WT_vs_EV_F02.20950.20950.2 7.21E-10 26-Dec R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.94 16770 20950 2 1661.88496 831.9481 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3848.7 - 1.81E+06 - - - 1.9436 - 2.431 0.578 - 392.8 1 2 0 0.0032 14 0 0 0 5.82E+07 6.20E+07 - - - 5.5382 0.8975 230117_WJC_METTL3_WT_vs_EV_F02.20951.20951.2 0.0107 16-Jul R.FYTLIPHDF.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1151.5651 - 16771 20951 2 1151.567235 576.7898 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.08 3848.8 - 751031 - - - 1.8132 - 1.127 0.364 - 114 1 1 0 0.0021 9 0 0 0 - - - - - 2.0747 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.20953.20953.3 0.00161 Oct-52 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.93 16773 20953 3 1661.88422 554.9679 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3848.9 - 401160 - - - 1.4983 - 2.054 0.453 - 114.3 1 2 0 0.0025 14 0 0 0 9.63E+06 1.04E+07 - - - 5.5027 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20963.20963.2 0.00433 28-Jul R.HFYWYLTNEGIQYLR[166.11].D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2011.982 -1 16783 20963 2 2011.983361 1006.9983 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3849.9 - 0 - - - 0.675 - 1.565 0.381 - 64.2 1 2 0 0.0014 15 0 0 0 0.00E+00 0.00E+00 - - - 2.9558 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20968.20968.3 0.000176 15/52 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.93 16786 20968 3 1669.894909 557.6393 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3850.7 - 4.16E+06 - - - -0.6114 - 2.086 0.409 - 286.5 1 2 0 -0.001 14 0 0 0 9.63E+06 1.04E+07 - - - 5.0536 1 230117_WJC_METTL3_WT_vs_EV_F02.20971.20971.2 0.000902 16-Nov K.TLDDLFPLR.S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1088.5866 1.01 16789 20971 2 1088.58889 545.3006 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.21 3850.9 - 2.23E+06 - - - 2.0945 - 2.314 0.459 - 404.8 1 2 0 0.0023 9 0 0 0 1.13E+07 1.12E+07 - - - 4.8577 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20972.20972.2 9.33E-05 16-Aug K.ITFLLQAIR.N "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1073.6597 1.41 16790 20972 2 1073.660495 537.8371 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 3850.9 - 2.06E+06 - - - 0.7256 - 1.96 0.308 - 198.9 1 2 0 0.0008 9 0 0 0 1.31E+07 9.33E+06 - - - 3.2625 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20973.20973.2 0.642 20-Nov K.VSVFFGGLSIK.K "sp|O00148|DX39A_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|A0A0D9SEM9|A0A0D9SEM9_HUMAN" 3 1152.6543 1.4 16791 20973 2 1152.655808 577.3344 ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2 8.72 3851 - 1.88E+06 - - - 1.3118 - 1.761 0.305 - 344.5 1 2 0 0.0015 11 0 0 0 9.48E+06 6.78E+06 - - - 2.8241 1 230117_WJC_METTL3_WT_vs_EV_F02.20974.20974.2 3.20E-05 20-Dec K.VAVFFGGLSIK[136.11].K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1144.6736 0.81 16792 20974 2 1144.673758 573.3441 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3851.1 - 1.84E+06 - - - 0.1546 - 2.573 0.562 - 561.5 1 2 0 0.0002 11 0 0 0 1.25E+07 1.55E+07 - - - 5.7485 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20975.20975.2 0.00272 16-Sep K.TLDDLFPLR[166.11].S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1098.5949 1.74 16793 20975 2 1098.595586 550.3047 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.21 3851.1 - 1.52E+06 - - - 0.6426 - 1.859 0.434 - 255.1 1 2 0 0.0007 9 0 0 0 9.78E+06 5.63E+06 - - - 4.0401 1 230117_WJC_METTL3_WT_vs_EV_F02.20976.20976.2 1.48E-05 20-Dec K.VAVFFGGLSIK.K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1136.6594 0.81 16794 20976 2 1136.660061 569.337 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3851.2 - 1.24E+06 - - - 0.5982 - 2.526 0.539 - 583.6 1 2 0 0.0007 11 0 0 0 1.25E+07 1.55E+07 - - - 5.5286 1 230117_WJC_METTL3_WT_vs_EV_F02.20977.20977.2 1.23E-05 24-Nov R.VLLFTDDVALVSK.A "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1418.8021 1.21 16795 20977 2 1418.80382 710.4083 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.21 3851.3 - 1.02E+06 - - - 1.225 - 2.497 0.637 - 267.6 1 2 0 0.0017 13 0 0 0 4.11E+06 3.38E+06 - - - 6.0939 1 230117_WJC_METTL3_WT_vs_EV_F02.20978.20978.2 0.00142 18-Dec R.DFILPISDVR.A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|Q4VXM0|Q4VXM0_HUMAN,tr|Q4VXM1|Q4VXM1_HUMAN" 5 1173.6394 2.54 16796 20978 2 1173.639512 587.827 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.21 3851.4 - 891474 - - - 0.1176 - 2.476 0.511 - 630.2 1 2 0 0.0001 10 0 0 0 1.44E+07 5.68E+06 - - - 5.3459 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.20979.20979.2 0.00171 14-Aug R.DFLLDIAR.Q "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 961.5233 1.39 16797 20979 2 961.525998 481.7689 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 3851.5 - 629143 - - - 2.8247 - 1.564 0.406 - 316.4 1 2 0 0.0027 8 0 0 0 1.71E+07 1.23E+07 - - - 3.3877 1 230117_WJC_METTL3_WT_vs_EV_F02.20981.20981.2 0.0783 18-Dec R.MALLATVLGR.F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1043.6161 2.36 16799 20981 2 1043.615625 522.8153 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.5 3851.7 - 474688 - - - -0.4896 - 2.418 0.451 - 630.6 1 2 0 -0.0005 10 0 0 0 2.15E+07 9.08E+06 - - - 4.8365 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.20983.20983.2 0.0024 22-Oct K.TLQTISLLGYMK.H sp|O60264|SMCA5_HUMAN 1 1366.753 -1 16801 20983 2 1366.759017 684.3838 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 8.26 3852 - 351319 - - - 4.3848 - 1.588 0.439 - 192.8 1 2 0 0.006 12 0 0 0 0.00E+00 0.00E+00 - - - 3.4984 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.20985.20985.3 0.00142 Sep-40 K.VPPPWLIAMQR.Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1306.722 -1 16803 20985 3 1306.724574 436.5813 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3852.2 - 272916 - - - 1.9713 - 2.053 0.352 - 135.4 1 2 0 0.0026 11 0 0 0 0.00E+00 0.00E+00 - - - 4.5072 1 230117_WJC_METTL3_WT_vs_EV_F02.20989.20989.2 6.52E-07 16/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 16806 20989 2 1343.613193 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3852.7 - 1.11E+06 - - - 1.2883 - 2.793 0.537 - 1007.8 1 1 0 0.0017 10 0 0 0 4.57E+06 0.00E+00 - - - 5.8737 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.20991.20991.2 0.0167 18-Dec R.SDLVLLYELK[136.11].Q sp|Q9NPF5|DMAP1_HUMAN 1 1199.6893 1.14 16808 20991 2 1199.691427 600.8519 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.37 3852.9 - 3.65E+06 - - - 1.7805 - 2.453 0.407 - 518.4 1 2 0 0.0021 10 0 0 0 1.39E+07 1.22E+07 - - - 4.5511 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.20992.20992.2 0.0527 16-Nov K.ITFLLQAIR[166.11].N "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1083.668 1.41 16809 20992 2 1083.668988 542.8413 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 3853 - 3.32E+06 - - - 0.9246 - 1.818 0.238 - 379.1 1 2 0 0.001 9 0 0 0 1.31E+07 9.33E+06 - - - 2.5278 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.20993.20993.2 0.0178 14-Jul R.DFLLDIAR[166.11].Q "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 971.5316 1.38 16810 20993 2 971.531781 486.7731 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 3853.2 - 2.35E+06 - - - 0.2357 - 1.363 0.341 - 198.3 1 2 0 0.0002 8 0 0 0 1.71E+07 1.23E+07 - - - 2.4936 1 230117_WJC_METTL3_WT_vs_EV_F02.20994.20994.2 6.47E-05 15/24 K.AAILPTSIFLTNK[136.11].K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1395.8217 0.49 16811 20994 2 1395.821566 698.9181 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3853.3 - 1.50E+06 - - - -0.0974 - 2.463 0.502 - 595.6 1 2 0 -0.0001 13 0 0 0 2.57E+07 5.24E+07 - - - 5.0621 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.20996.20996.2 1.96 18-Dec R.MALLATVLGR[166.11].F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1053.6244 2.36 16813 20996 2 1053.625 527.8195 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.5 3853.6 - 1.19E+06 - - - 0.5638 - 2.213 0.314 - 652 1 2 0 0.0006 10 0 0 0 2.15E+07 9.08E+06 - - - 3.5773 1 230117_WJC_METTL3_WT_vs_EV_F02.21004.21004.2 2.49E-07 26-Sep R.WEGPLSVSVFAATK.E sp|O43505|B4GA1_HUMAN 1 1490.7769 1.1 16821 21004 2 1490.78021 746.3957 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 6 3854.6 - 376243 - - - 2.2002 - 2.151 0.588 - 199.8 1 2 0 0.0033 14 0 0 0 1.99E+06 1.81E+06 - - - 5.305 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.21011.21011.2 0.00159 12-Aug K.YFLWVVK.F sp|P62993|GRB2_HUMAN 1 953.5375 3.69 16827 21011 2 953.53716 477.776 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 8.59 3855.6 - 611849 - - - -0.3303 - 1.446 0.298 - 207.2 1 2 0 -0.0003 7 0 0 0 4.46E+06 1.21E+06 - - - 2.4105 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21012.21012.2 4.84E-05 24-Nov K.AAILPTSIFLTNK.K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1387.8075 0.49 16828 21012 2 1387.80802 694.911 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3855.7 - 4.54E+06 - - - 0.3733 - 2.232 0.456 - 298.5 1 2 0 0.0005 13 0 0 0 2.57E+07 5.24E+07 - - - 4.4695 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21013.21013.2 0.000159 20-Sep R.TSLGNVVLLLK.S "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1155.7227 1.74 16829 21013 2 1155.722985 578.8686 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 8.41 3855.7 - 4.26E+06 - - - 0.2379 - 2.083 0.441 - 214.9 1 2 0 0.0003 11 0 0 0 1.35E+07 7.75E+06 - - - 4.2833 0.9987 230117_WJC_METTL3_WT_vs_EV_F02.21014.21014.2 0.908 16-Aug R.DLLFQALGR.T sp|Q9NSD9|SYFB_HUMAN 1 1031.5764 3.86 16830 21014 2 1031.578372 516.7955 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 5.84 3855.8 - 3.94E+06 - - - 1.931 - 1.59 0.251 - 196.2 1 2 0 0.002 9 0 0 0 1.78E+07 4.63E+06 - - - 2.2359 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21015.21015.2 0.0019 20-Oct R.TSLGNVVLLLK[136.11].S "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1163.7369 1.74 16831 21015 2 1163.737291 582.8757 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 8.41 3855.9 - 2.48E+06 - - - 0.3274 - 2.047 0.393 - 222.9 1 2 0 0.0004 11 0 0 0 1.35E+07 7.75E+06 - - - 3.8815 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21016.21016.2 0.000511 18-Aug R.DFILPISDVR[166.11].A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|Q4VXM0|Q4VXM0_HUMAN,tr|Q4VXM1|Q4VXM1_HUMAN" 5 1183.6476 2.89 16832 21016 2 1183.647571 592.8311 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.21 3855.9 - 2.14E+06 - - - -0.0617 - 1.866 0.426 - 224.4 1 2 0 -0.0001 10 0 0 0 1.66E+07 5.72E+06 - - - 3.9286 1 230117_WJC_METTL3_WT_vs_EV_F02.21017.21017.2 9.80E-10 13/22 K.ITAEEMYDIFGK.Y sp|Q9Y3B4|SF3B6_HUMAN 1 1415.6643 2.12 16833 21017 2 1415.663782 708.8394 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.14 3856 - 2.13E+06 - - - -0.3433 - 2.727 0.657 - 726 1 2 0 -0.0005 12 0 0 0 5.49E+06 2.59E+06 - - - 6.533 1 230117_WJC_METTL3_WT_vs_EV_F02.21018.21018.2 0.000119 20-Nov R.FDEISFVNFAR[166.11].G sp|Q08945|SSRP1_HUMAN 1 1353.6593 0.83 16834 21018 2 1353.658341 677.8369 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3856.1 - 1.81E+06 - - - -0.687 - 2.226 0.462 - 546.3 1 2 0 -0.0009 11 0 0 0 6.80E+06 8.15E+06 - - - 4.6178 1 230117_WJC_METTL3_WT_vs_EV_F02.21021.21021.2 4.25E-05 15/24 K.IAVPLIQGYTVLR[166.11].L sp|Q8IW92|GLBL2_HUMAN 1 1451.874 0.91 16837 21021 2 1451.878058 726.9443 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3856.5 - 1.33E+06 - - - 2.8253 - 2.392 0.49 - 762.1 1 2 0 0.0041 13 0 0 0 4.56E+06 4.99E+06 - - - 4.8972 1 230117_WJC_METTL3_WT_vs_EV_F02.21022.21022.2 3.47E-07 22-Nov K.ITAEEMYDIFGK[136.11].Y sp|Q9Y3B4|SF3B6_HUMAN 1 1423.6785 2.12 16838 21022 2 1423.677993 712.8465 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.14 3856.6 - 1.10E+06 - - - -0.3336 - 2.486 0.619 - 515.1 1 2 0 -0.0005 12 0 0 0 5.49E+06 2.59E+06 - - - 6.0089 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21023.21023.2 0.00142 24-Dec K.IAVPLIQGYTVLR.L sp|Q8IW92|GLBL2_HUMAN 1 1441.8657 0.92 16839 21023 2 1441.865828 721.9401 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3856.7 - 1.03E+06 - - - 0.0985 - 2.158 0.447 - 478.6 1 2 0 0.0001 13 0 0 0 4.59E+06 4.99E+06 - - - 4.3166 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.21024.21024.2 0.00148 24-Oct K.LIHIPINNIIVGG.- sp|P60059|SC61G_HUMAN 1 1371.8238 - 16840 21024 2 1371.827735 686.9192 Protein transport protein Sec61 subunit gamma OS=Homo sapiens OX=9606 GN=SEC61G PE=1 SV=1 6.74 3856.9 - 900001 - - - 2.8531 - 2.023 0.394 - 227.8 1 2 0 0.0039 13 0 0 0 - - - - - 3.7582 0.9817 230117_WJC_METTL3_WT_vs_EV_F02.21026.21026.2 0.00317 16-Oct K.LGAFLWMQR.N "sp|Q96EI5|TCAL4_HUMAN,sp|Q9H3H9|TCAL2_HUMAN,tr|A2RQR6|A2RQR6_HUMAN" 3 1120.5852 -1 16842 21026 2 1120.57861 561.2999 Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2 9.75 3857.1 - 680480 - - - -5.8541 - 2.094 0.375 - 455.9 1 2 0 -0.0066 9 0 0 0 0.00E+00 0.00E+00 - - - 3.9469 0.9942 230117_WJC_METTL3_WT_vs_EV_F02.21034.21034.2 0.00021 20-Dec R.FDEISFVNFAR.G sp|Q08945|SSRP1_HUMAN 1 1343.651 0.83 16848 21034 2 1343.659272 672.8328 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3858 - 524917 - - - 6.1556 - 1.926 0.383 - 383 1 2 0 0.0083 11 0 0 0 6.87E+06 8.32E+06 - - - 3.6404 1 230117_WJC_METTL3_WT_vs_EV_F02.21036.21036.2 1.84E-08 17/28 K.VILESEVIAEAVGVK.K sp|O15226|NKRF_HUMAN 1 1554.8869 1.04 16850 21036 2 1554.889703 778.4507 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.25 3858.2 - 379027 - - - 1.8188 - 3.461 0.642 - 756.1 1 2 0 0.0028 15 0 0 0 9.29E+06 8.94E+06 - - - 6.8344 0.9978 230117_WJC_METTL3_WT_vs_EV_F02.21039.21039.2 0.113 20-Sep K.VPPPWLIAMQR[166.11].Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1316.7303 1.3 16853 21039 2 1316.73141 659.3724 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3858.6 - 223851 - - - 0.8673 - 1.528 0.2 - 234.4 1 2 0 0.0011 11 0 0 0 1.37E+07 1.06E+07 - - - 1.6648 0.999 230117_WJC_METTL3_WT_vs_EV_F02.21057.21057.2 0.0013 14-Aug R.TLFGFLGK.L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 881.5011 1.52 16868 21057 2 881.503339 441.7578 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3860.8 - 255730 - - - 2.5513 - 1.41 0.36 - 180.7 1 2 0 0.0022 8 0 0 0 2.57E+07 1.69E+07 - - - 2.7355 1 230117_WJC_METTL3_WT_vs_EV_F02.21058.21058.2 2.52E-09 14/26 K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 15.48 16869 21058 2 1613.794602 807.9078 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3861 - 1.71E+06 - - - -4.024 - 2.399 0.561 - 451.5 1 2 0 -0.0065 14 0 0 0 5.91E+08 3.82E+07 - - - 5.3784 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21059.21059.2 0.000329 13/20 K.LEDVLPLAFTR.L "sp|Q5SSJ5|HP1B3_HUMAN,tr|B0QZK4|B0QZK4_HUMAN,tr|Q5SWC8|Q5SWC8_HUMAN" 3 1272.7078 0.8 16870 21059 2 1272.70858 637.3612 Heterochromatin protein 1-binding protein 3 OS=Homo sapiens OX=9606 GN=HP1BP3 PE=1 SV=1 4.37 3861.1 - 738113 - - - 0.6223 - 2.494 0.371 - 580.7 1 2 0 0.0008 11 0 0 0 6.78E+06 8.49E+06 - - - 4.2532 1 230117_WJC_METTL3_WT_vs_EV_F02.21060.21060.2 2.80E-06 14/20 R.PLEVFMC[160.03]SVLK[136.11].R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1329.6916 4.76 16871 21060 2 1329.688955 665.8531 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.38 3861.2 - 533881 - - - -2.0012 - 2.681 0.616 - 622.6 1 1 0 -0.0027 11 0 0 0 3.28E+07 6.88E+06 - - - 6.2578 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21061.21061.3 1.28E-06 14/52 K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 15.16 16872 21061 3 1613.799487 538.941 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3861.3 - 486291 - - - -0.997 - 2.527 0.573 - 297.5 1 2 0 -0.0016 14 0 0 0 1.40E+08 9.22E+06 - - - 7.3916 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21063.21063.2 0.000228 13/20 R.DSLIFLVDASK[136.11].A sp|P12956|XRCC6_HUMAN 1 1214.6638 0.81 16874 21063 2 1214.664946 608.3392 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.21 3861.6 - 469084 - - - 0.9402 - 2.195 0.35 - 459 1 2 0 0.0011 11 0 0 0 2.54E+07 3.12E+07 - - - 3.7525 1 230117_WJC_METTL3_WT_vs_EV_F02.21065.21065.2 3.23E-07 13/26 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 4.42 16876 21065 2 1535.794005 768.9025 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3861.9 - 364364 - - - 2.2614 - 2.37 0.515 - 470 1 2 0 0.0035 14 0 0 0 6.46E+07 1.46E+07 - - - 5.0091 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21066.21066.2 0.00765 16-Sep R.DIVQFVPFR[166.11].E "sp|Q96FN4|CPNE2_HUMAN,sp|O75131|CPNE3_HUMAN,sp|O95741|CPNE6_HUMAN,sp|Q86YQ8|CPNE8_HUMAN,sp|Q8IYJ1|CPNE9_HUMAN,sp|Q9UBL6|CPNE7_HUMAN,sp|Q9HCH3|CPNE5_HUMAN,sp|Q96A23|CPNE4_HUMAN,tr|E7ENV7|E7ENV7_HUMAN" 9 1129.616 3.01 16877 21066 2 1129.616516 565.8153 Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3 5.84 3862 - 339277 - - - 0.5011 - 1.841 0.377 - 317.8 1 2 0 0.0006 9 0 0 0 8.33E+06 2.77E+06 - - - 3.591 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21068.21068.2 0.00577 20-Dec R.ILEFIAVSQLR.G "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN,tr|K7ER27|K7ER27_HUMAN" 4 1287.7551 1.03 16879 21068 2 1287.755918 644.8848 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 6 3862.3 - 289734 - - - 0.6562 - 2.334 0.437 - 615.8 1 2 0 0.0008 11 0 0 0 3.01E+06 2.92E+06 - - - 4.5613 0.9716 230117_WJC_METTL3_WT_vs_EV_F02.21071.21071.2 1.45 24-Dec R.VIYAMAEDGLLFK.F "sp|P30825|SL7A1_HUMAN,sp|P52569|CTR2_HUMAN,tr|A0A1W2PR06|A0A1W2PR06_HUMAN" 3 1468.7636 8.89 16882 21071 2 1468.764058 735.3891 High affinity cationic amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A1 PE=1 SV=1 4.37 3862.6 - 250684 - - - 0.32 - 1.333 0.019 - 190.4 1 2 0 0.0005 13 0 0 0 1.20E+07 1.35E+06 - - - -0.0811 0.997 230117_WJC_METTL3_WT_vs_EV_F02.21073.21073.2 0.0593 24-Jun R.VIYAMAEDGLLFK[136.11].F "sp|P30825|SL7A1_HUMAN,sp|P52569|CTR2_HUMAN,tr|A0A1W2PR06|A0A1W2PR06_HUMAN" 3 1476.7778 8.73 16884 21073 2 1476.780591 739.3962 High affinity cationic amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A1 PE=1 SV=1 4.37 3862.9 - 230948 - - - 1.8981 - 1.235 0.268 - 66.9 2 2 0 0.0028 13 0 0 0 1.18E+07 1.35E+06 - - - 1.4268 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.21077.21077.3 0.000891 Dec-36 K.YRPLFDYFLK.C "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 1360.718 1.29 16887 21077 3 1360.716952 454.5799 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.5 3863.4 - 28885.4 - - - -0.7401 - 2.117 0.289 - 174.6 1 2 0 -0.001 10 0 0 0 2.26E+06 1.75E+06 - - - 3.9521 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.21081.21081.2 0.28 14-Aug K.VALLDVFR[166.11].E "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 941.5574 2.62 16891 21081 2 941.559256 471.786 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.81 3863.7 - 278832 - - - 2.0009 - 1.858 0.226 - 325.9 1 2 0 0.0019 8 0 0 0 5.12E+07 1.95E+07 - - - 2.578 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.21083.21083.2 0.0072 14-Sep R.VFLWGSFR[166.11].D "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1020.5421 1.07 16893 21083 2 1020.543892 511.2783 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 9.72 3863.9 - 232400 - - - 1.7981 - 1.54 0.302 - 409.8 1 2 0 0.0018 8 0 0 0 4.68E+06 4.38E+06 - - - 2.5732 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.21085.21085.2 1.10E-05 16-Sep K.YPENFFLLR.G "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|C9J9S3|C9J9S3_HUMAN,tr|E7ETD8|E7ETD8_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 12 1197.6182 8.2 16895 21085 2 1197.615558 599.8164 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 6 3864.1 - 87828.5 - - - -2.2436 - 1.869 0.505 - 358.4 1 2 0 -0.0027 9 0 0 0 2.85E+06 3.48E+05 - - - 4.5794 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.21087.21087.2 0.000585 26-Nov K.EILALIPNQNALLK.D sp|Q7L2Z9|CENPQ_HUMAN 1 1548.9239 -1 16897 21087 2 1548.928787 775.4692 Centromere protein Q OS=Homo sapiens OX=9606 GN=CENPQ PE=1 SV=1 6.1 3864.3 - 49701.9 - - - 3.1364 - 2.184 0.401 - 304.4 1 2 0 0.0049 14 0 0 0 0.00E+00 0.00E+00 - - - 3.9615 0.999 230117_WJC_METTL3_WT_vs_EV_F02.21091.21091.2 0.00272 14-Aug R.TLFGFLGK[136.11].L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 889.5153 1.51 16899 21091 2 889.515253 445.7649 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3864.8 - 1.59E+06 - - - -0.0416 - 1.444 0.368 - 179 1 2 0 0 8 0 0 0 2.56E+07 1.69E+07 - - - 2.8671 1 230117_WJC_METTL3_WT_vs_EV_F02.21092.21092.2 0.000915 14/22 K.TLGVDLVALATR[166.11].V "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1237.727 2.66 16900 21092 2 1237.728525 619.8708 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.5 3864.8 - 1.66E+06 - - - 1.2668 - 2.489 0.463 - 601.6 1 2 0 0.0016 12 0 0 0 4.29E+07 1.61E+07 - - - 4.8595 1 230117_WJC_METTL3_WT_vs_EV_F02.21095.21095.3 4.25E-10 16/52 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 5.18 16903 21095 3 1535.791078 512.9375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3865.2 - 536198 - - - 0.3555 - 2.979 0.599 - 399.9 1 2 0 0.0005 14 0 0 0 1.17E+07 2.26E+06 - - - 8.119 1 230117_WJC_METTL3_WT_vs_EV_F02.21096.21096.2 8.24E-07 13/26 K.TFAPEEISAMVLTK[136.11].M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1543.8047 4.42 16904 21096 2 1543.802157 772.9096 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3865.2 - 533653 - - - -1.668 - 2.221 0.537 - 451.6 1 2 0 -0.0026 14 0 0 0 6.46E+07 1.46E+07 - - - 5.0089 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21097.21097.2 1.24E-05 20-Oct K.DFPLSGYVELR.Y sp|O75489|NDUS3_HUMAN 1 1294.6558 1.7 16905 21097 2 1294.657227 648.3352 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 4.37 3865.4 - 377131 - - - 1.1393 - 1.902 0.414 - 354.5 1 2 0 0.0015 11 0 0 0 7.24E+06 4.25E+06 - - - 3.8376 1 230117_WJC_METTL3_WT_vs_EV_F02.21099.21099.2 5.27E-05 24-Dec R.GLAFELVYSPAIK.D "sp|P78346|RPP30_HUMAN,tr|Q5VU11|Q5VU11_HUMAN,tr|Q5VU10|Q5VU10_HUMAN" 3 1406.781 1.74 16907 21099 2 1406.784845 704.3978 Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1 6 3865.6 - 217311 - - - 2.7666 - 2.39 0.469 - 442.2 1 2 0 0.0039 13 0 0 0 2.11E+06 1.21E+06 - - - 4.74 0.9907 230117_WJC_METTL3_WT_vs_EV_F02.21102.21102.2 0.156 20-Aug K.YLLLSDLPGVR.E "sp|Q99766|ATP5S_HUMAN,tr|A0A5K1VW60|A0A5K1VW60_HUMAN,tr|A0A2R8YDJ1|A0A2R8YDJ1_HUMAN" 3 1244.7129 -1 16910 21102 2 1244.718601 623.3637 "ATP synthase subunit s, mitochondrial OS=Homo sapiens OX=9606 GN=DMAC2L PE=1 SV=3" 5.84 3866 - 699634 - - - 4.6019 - 1.465 0.239 - 189.6 1 2 0 0.0057 11 0 0 0 0.00E+00 0.00E+00 - - - 1.8375 0.9946 230117_WJC_METTL3_WT_vs_EV_F02.21103.21103.2 0.0205 24-Nov R.LIGEMNSLFDEVR.Q "sp|Q9P2W9|STX18_HUMAN,tr|D6RF48|D6RF48_HUMAN" 2 1521.7497 -1 16911 21103 2 1521.756134 761.8821 Syntaxin-18 OS=Homo sapiens OX=9606 GN=STX18 PE=1 SV=1 4.14 3866.1 - 238028 - - - 4.209 - 1.389 0.3 - 138 1 2 0 0.0064 13 0 0 0 0.00E+00 0.00E+00 - - - 2.0981 1 230117_WJC_METTL3_WT_vs_EV_F02.21105.21105.2 2.28E-08 14/28 K.LLDTVDDMLANDIAR[166.11].L "sp|Q9H4M9|EHD1_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 3 1683.8377 -1 16913 21105 2 1683.828217 842.9261 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 3.77 3866.3 - 0 - - - -5.6353 - 2.982 0.531 - 319.7 1 2 0 -0.0095 15 0 0 0 0.00E+00 0.00E+00 - - - 5.6462 0.9622 230117_WJC_METTL3_WT_vs_EV_F02.21106.21106.3 0.159 Jul-44 K.TLGVDLVALATR.V "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1227.7187 -1 16914 21106 3 1227.719864 410.2468 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.5 3866.5 - 40061.3 - - - 0.9587 - 1.081 0.171 - 53.1 1 2 0 0.0012 12 0 0 0 0.00E+00 0.00E+00 - - - 0.662 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21108.21108.2 0.00104 20-Dec R.DSLIFLVDASK.A sp|P12956|XRCC6_HUMAN 1 1206.6496 0.81 16915 21108 2 1206.651098 604.3321 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.21 3866.8 - 4.38E+06 - - - 1.2381 - 2.473 0.392 - 438.9 1 2 0 0.0015 11 0 0 0 2.54E+07 3.12E+07 - - - 4.3853 1 230117_WJC_METTL3_WT_vs_EV_F02.21110.21110.2 3.11E-10 19/28 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 3.41 16917 21110 2 1700.895492 851.4565 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3867 - 5.06E+06 - - - -1.7697 - 3.549 0.648 - 1015.3 1 2 0 -0.003 15 0 0 0 3.00E+08 8.79E+07 - - - 6.9403 1 230117_WJC_METTL3_WT_vs_EV_F02.21111.21111.2 2.42E-06 18/28 R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 3.41 16918 21111 2 1710.902752 856.4607 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3867.2 - 1.77E+06 - - - -2.3496 - 3.463 0.565 - 893.4 1 2 0 -0.004 15 0 0 0 3.00E+08 8.79E+07 - - - 6.2667 1 230117_WJC_METTL3_WT_vs_EV_F02.21113.21113.3 9.49E-08 18/56 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 4.52 16920 21113 3 1700.897575 567.9734 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3867.4 - 1.57E+06 - - - -0.545 - 3.202 0.599 - 543.9 1 2 0 -0.0009 15 0 0 0 5.82E+07 1.29E+07 - - - 8.2547 1 230117_WJC_METTL3_WT_vs_EV_F02.21114.21114.2 4.91E-09 13/26 K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 15.4 16921 21114 2 1621.811846 811.9149 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3867.6 - 1.41E+06 - - - -2.1272 - 2.438 0.663 - 344.4 1 2 0 -0.0034 14 0 0 0 5.87E+08 3.81E+07 - - - 6.1732 1 230117_WJC_METTL3_WT_vs_EV_F02.21115.21115.2 4.06E-06 18-Dec R.WYEWLDPSIK.K sp|Q99459|CDC5L_HUMAN 1 1335.6499 0.93 16922 21115 2 1335.64969 668.8322 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3867.7 - 1.16E+06 - - - -0.1864 - 2.001 0.526 - 492.1 1 2 0 -0.0002 10 0 0 0 5.06E+06 5.43E+06 - - - 4.8621 1 230117_WJC_METTL3_WT_vs_EV_F02.21116.21116.2 6.81E-07 13/26 K.LFIYNPTTGEFLGR.T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1626.8406 1.67 16923 21116 2 1626.83681 814.4276 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3867.8 - 1.02E+06 - - - -2.3254 - 2.573 0.547 - 433.9 1 2 0 -0.0038 14 0 0 0 1.99E+07 1.19E+07 - - - 5.4516 1 230117_WJC_METTL3_WT_vs_EV_F02.21117.21117.2 2.19E-07 19/28 K.VSALDLAVLDQVEAR.L "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 6 1597.8675 9.01 16924 21117 2 1597.872764 799.941 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.03 3868 - 701948 - - - 3.2719 - 3.818 0.515 - 1443.5 1 2 0 0.0052 15 0 0 0 3.35E+06 3.71E+05 - - - 6.1369 0.8931 230117_WJC_METTL3_WT_vs_EV_F02.21118.21118.2 5.67 22-Jul R.TNVINEILSTER[166.11].D "sp|Q9NR80|ARHG4_HUMAN,tr|A0A0C4DFY6|A0A0C4DFY6_HUMAN,tr|A0A087X0P1|A0A087X0P1_HUMAN,tr|E9PEM0|E9PEM0_HUMAN,tr|E7EV07|E7EV07_HUMAN" 5 1397.739 0.8 16925 21118 2 1397.737418 699.8768 Rho guanine nucleotide exchange factor 4 OS=Homo sapiens OX=9606 GN=ARHGEF4 PE=1 SV=3 4.53 3868.1 - 655879 - - - -1.1161 - 1.247 0.01 - 126.5 2 2 0 -0.0016 12 0 0 0 5.96E+06 7.46E+06 - - - -0.4393 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21119.21119.3 1.53E-05 19/56 R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 4.52 16926 21119 3 1710.90651 571.3095 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3868.2 - 539614 - - - -0.1531 - 3.16 0.456 - 502.1 1 2 0 -0.0003 15 0 0 0 5.82E+07 1.29E+07 - - - 6.6261 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.21121.21121.2 0.0302 14-Jul R.IPFTFWAR.Y sp|Q9Y5V3|MAGD1_HUMAN 1 1036.5494 0.97 16928 21121 2 1036.550502 519.282 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 9.75 3868.5 - 487825 - - - 1.0274 - 1.434 0.36 - 178.3 1 2 0 0.0011 8 0 0 0 4.62E+06 4.77E+06 - - - 2.7868 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.21122.21122.3 0.000278 14/52 K.TFAPEEISAMVLTK[136.11].M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1543.8047 5.18 16929 21122 3 1543.802582 515.6089 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3868.6 - 468083 - - - -1.3927 - 1.965 0.368 - 113.4 1 2 0 -0.0021 14 0 0 0 1.17E+07 2.26E+06 - - - 4.4374 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21123.21123.3 1.08E-06 14/52 K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 15.16 16930 21123 3 1621.813655 541.6124 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3868.7 - 465286 - - - -1.0118 - 2.527 0.532 - 260.7 1 2 0 -0.0016 14 0 0 0 1.40E+08 9.22E+06 - - - 6.9344 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21126.21126.2 0.000632 22-Dec K.VPDGMVGFIIGR[166.11].G "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 3 1269.6779 5.68 16933 21126 2 1269.677716 635.8462 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 5.81 3869.1 - 363246 - - - -0.1433 - 2.022 0.405 - 334.3 1 2 0 -0.0002 12 0 0 0 1.58E+07 2.78E+06 - - - 3.8848 1 230117_WJC_METTL3_WT_vs_EV_F02.21132.21132.2 2.02E-06 15/26 K.LFIYNPTTGEFLGR[166.11].T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1636.8489 1.67 16938 21132 2 1636.843806 819.4317 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3869.9 - 1.71E+06 - - - -3.0895 - 2.639 0.546 - 564.7 1 2 0 -0.0051 14 0 0 0 1.99E+07 1.19E+07 - - - 5.5073 1 230117_WJC_METTL3_WT_vs_EV_F02.21134.21134.2 2.51E-06 15/26 R.VLLATLSIPITPER.T sp|Q14152|EIF3A_HUMAN 1 1521.913 0.92 16940 21134 2 1521.913355 761.9638 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3870.1 - 916650 - - - 0.2135 - 3.041 0.536 - 658 1 2 0 0.0003 14 0 0 0 2.09E+07 2.26E+07 - - - 5.7908 1 230117_WJC_METTL3_WT_vs_EV_F02.21135.21135.2 3.97E-06 13/22 R.LEGLTDEINFLR[166.11].Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1428.7488 1.6 16941 21135 2 1428.747247 715.3817 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3870.2 - 640511 - - - -1.0975 - 2.732 0.48 - 721.9 1 2 0 -0.0016 12 0 0 0 1.06E+07 6.62E+06 - - - 5.2302 1 230117_WJC_METTL3_WT_vs_EV_F02.21138.21138.2 5.68E-07 14/26 R.VFGAPEVLENLEVK[136.11].S sp|Q8TEM1|PO210_HUMAN 1 1550.8436 -1 16944 21138 2 1550.841615 776.4291 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.25 3870.6 - 336382 - - - -1.2542 - 2.498 0.508 - 502.9 1 2 0 -0.0019 14 0 0 0 0.00E+00 0.00E+00 - - - 5.0899 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21141.21141.2 3.03E-05 24-Nov R.APLPDLYPFGTMR.G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1476.7435 1.64 16947 21141 2 1476.744556 739.379 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3871 - 255953 - - - 0.7002 - 2.049 0.462 - 359.7 1 2 0 0.001 13 0 0 0 6.92E+06 4.22E+06 - - - 4.2941 0.9852 230117_WJC_METTL3_WT_vs_EV_F02.21148.21148.2 0.00157 30-Jun R.VFVPLPGSTVMLC[160.03]DYK.F sp|Q5SWX8|ODR4_HUMAN 1 1824.9154 -1 16954 21148 2 1824.906166 913.465 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 5.8 3871.9 - 144095 - - - -5.0682 - 1.412 0.483 - 53.6 1 2 0 -0.0092 16 0 0 0 0.00E+00 0.00E+00 - - - 3.4538 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.21152.21152.2 0.00822 20-Sep R.GVTFLFPIQAK[136.11].T sp|Q9NR30|DDX21_HUMAN 1 1227.7107 0.87 16957 21152 2 1227.711232 614.8626 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3872.5 - 1.02E+07 - - - 0.4374 - 1.835 0.349 - 305.1 1 2 0 0.0005 11 0 0 0 3.33E+07 3.83E+07 - - - 3.2607 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.21153.21153.2 0.000125 20-Dec R.GVTFLFPIQAK.T sp|Q9NR30|DDX21_HUMAN 1 1219.6965 0.81 16958 21153 2 1219.696636 610.8555 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3872.5 - 7.43E+06 - - - 0.1156 - 2.209 0.256 - 552 1 2 0 0.0001 11 0 0 0 3.41E+07 4.23E+07 - - - 3.0758 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.21154.21154.2 4.50E-05 20-Sep K.SGAYLIPLLER[166.11].L "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1240.7055 1.25 16959 21154 2 1240.706185 621.36 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.72 3872.5 - 5.13E+06 - - - 0.5577 - 1.886 0.253 - 270.1 1 2 0 0.0007 11 0 0 0 5.17E+07 4.15E+07 - - - 2.6258 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21157.21157.2 0.00351 18-Oct K.FSLFAGGMLR.V sp|Q9BVK6|TMED9_HUMAN 1 1097.5692 1.28 16962 21157 2 1097.5693 549.7919 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 9.75 3872.7 - 3.42E+06 - - - 0.1039 - 2.058 0.409 - 391.8 1 2 0 0.0001 10 0 0 0 7.31E+06 5.70E+06 - - - 4.0764 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21158.21158.2 0.00398 16-Sep R.IIFVDEVFK[136.11].L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1116.631 -1 16963 21158 2 1116.631671 559.3228 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 4.37 3872.8 - 2.14E+06 - - - 0.5579 - 1.84 0.458 - 203 1 2 0 0.0006 9 0 0 0 0.00E+00 0.00E+00 - - - 4.1877 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.21159.21159.2 0.000983 14-Sep R.FPLFGGWK[136.11].T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 958.5156 -1 16964 21159 2 958.515212 480.2651 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3872.9 - 1.93E+06 - - - -0.4298 - 1.643 0.407 - 332.2 1 2 0 -0.0004 8 0 0 0 0.00E+00 0.00E+00 - - - 3.5445 0.939 230117_WJC_METTL3_WT_vs_EV_F02.21161.21161.2 0.00328 12-Aug Y.SSFLFWR.M sp|Q13015|AF1Q_HUMAN 1 941.4759 999 16966 21161 2 941.475186 471.7452 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 9.47 3873 - 1.09E+06 - - - -0.7987 - 1.76 0.407 - 279.9 1 1 0 -0.0008 7 0 0 0 2.78E+06 0.00E+00 - - - 3.8381 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.21162.21162.2 0.000229 18-Oct K.YLMIEEYLTK.E sp|O95817|BAG3_HUMAN 1 1301.6577 6.38 16967 21162 2 1301.654886 651.8361 BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3 4.53 3873.2 - 989652 - - - -2.1818 - 1.853 0.481 - 276.4 1 2 0 -0.0028 10 0 0 0 2.28E+06 3.57E+05 - - - 4.3145 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.21164.21164.2 0.0437 18-Aug K.FEELNMDLFR[166.11].S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1322.6204 4.48 16969 21164 2 1322.621076 662.3175 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.14 3873.3 - 760809 - - - 0.4786 - 1.922 0.294 - 189.4 1 2 0 0.0006 10 0 0 0 1.54E+07 3.43E+06 - - - 3.036 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21165.21165.3 0.00799 13/44 R.LLALLDALASHK[136.11].A "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 1271.7693 -1 16970 21165 3 1271.768828 424.9304 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6.74 3873.5 - 693302 - - - -0.3499 - 2.111 0.35 - 195.1 1 2 0 -0.0004 12 0 0 0 0.00E+00 0.00E+00 - - - 4.5131 1 230117_WJC_METTL3_WT_vs_EV_F02.21166.21166.2 3.65E-05 15/26 R.IADQFLGAMYTLPR.Q "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN,tr|R4GMP9|R4GMP9_HUMAN" 3 1594.8177 999 16971 21166 2 1594.818136 798.4162 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 5.84 3873.6 - 673200 - - - 0.2427 - 3.178 0.381 - 759.8 1 2 0 0.0004 14 0 0 0 1.71E+06 0.00E+00 - - - 4.7565 0.9847 230117_WJC_METTL3_WT_vs_EV_F02.21167.21167.2 0.0589 14-Jun R.EGLLAIFK[136.11].S "sp|P35222|CTNB1_HUMAN,sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|C9J826|C9J826_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 15 897.5415 -1 16972 21167 2 897.539132 449.778 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 6.1 3873.7 - 655037 - - - -2.6428 - 1.272 0.264 - 105.5 1 2 0 -0.0024 8 0 0 0 0.00E+00 0.00E+00 - - - 1.7158 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.21168.21168.2 0.014 22-Jul R.VTGVPLSYLLSR.G "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1303.75 2.97 16973 21168 2 1303.750742 652.8823 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.72 3873.8 - 622519 - - - 0.5791 - 1.511 0.187 - 116.2 1 2 0 0.0008 12 0 0 0 1.42E+06 4.80E+05 - - - 1.508 0.9748 230117_WJC_METTL3_WT_vs_EV_F02.21169.21169.2 0.0408 18-Jun R.LPLVVEDFVK.D "sp|Q8NB37|GALD1_HUMAN,tr|H0YF25|H0YF25_HUMAN,tr|H0YE25|H0YE25_HUMAN,tr|H0YER3|H0YER3_HUMAN" 4 1157.6696 -1 16974 21169 2 1157.66613 579.8421 Glutamine amidotransferase-like class 1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GATD1 PE=1 SV=1 4.37 3873.9 - 496695 - - - -3.0078 - 1.322 0.224 - 63.8 1 2 0 -0.0035 10 0 0 0 0.00E+00 0.00E+00 - - - 1.4736 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21171.21171.2 0.000998 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 16975 21171 2 1603.765241 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3874.1 - 1.10E+08 - - - 0.8112 - 1.873 0.482 - 229 1 2 0 0.0013 12 0 0 0 8.20E+08 0.00E+00 - - - 4.2518 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21172.21172.2 0.000969 18-Oct K.FEELNMDLFR.S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1312.6122 4.07 16976 21172 2 1312.61189 657.3134 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.14 3874.2 - 5.71E+06 - - - -0.2156 - 2.182 0.433 - 372.1 1 2 0 -0.0003 10 0 0 0 1.54E+07 3.80E+06 - - - 4.4169 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21173.21173.2 0.000334 16-Sep R.IIFVDEVFK.L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1108.6168 3.83 16977 21173 2 1108.61795 555.3157 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 4.37 3874.2 - 2.29E+06 - - - 0.994 - 1.632 0.386 - 192.8 1 2 0 0.0011 9 0 0 0 1.87E+07 4.88E+06 - - - 3.3087 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.21174.21174.2 0.0385 14-Aug K.FYSFLVLK.K "sp|Q9H4I0|RD21L_HUMAN,sp|O60216|RAD21_HUMAN,tr|A0A804HJ87|A0A804HJ87_HUMAN,tr|E5RI01|E5RI01_HUMAN,tr|E5RG18|E5RG18_HUMAN,tr|E5RFZ5|E5RFZ5_HUMAN" 6 1015.5743 2.56 16978 21174 2 1015.575325 508.7944 Double-strand-break repair protein rad21-like protein 1 OS=Homo sapiens OX=9606 GN=RAD21L1 PE=2 SV=3 8.59 3874.3 - 2.21E+06 - - - 1.0536 - 1.525 0.295 - 149.5 1 2 0 0.0011 8 0 0 0 8.99E+06 3.51E+06 - - - 2.4922 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.21175.21175.2 0.00553 14-Sep R.FPLFGGWK.T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 950.5014 1.23 16979 21175 2 950.502113 476.258 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3874.4 - 1.83E+06 - - - 0.7249 - 1.625 0.333 - 286.9 1 2 0 0.0007 8 0 0 0 2.56E+07 2.08E+07 - - - 2.9646 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21176.21176.2 0.000216 20-Dec R.SGIVEYLSLVK.G "sp|P49642|PRI1_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN,tr|F8VNY2|F8VNY2_HUMAN" 3 1206.686 1.97 16980 21176 2 1206.689927 604.3503 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 5.72 3874.5 - 1.04E+06 - - - 3.2627 - 2.253 0.45 - 326.9 1 2 0 0.0039 11 0 0 0 2.81E+06 1.43E+06 - - - 4.5608 1 230117_WJC_METTL3_WT_vs_EV_F02.21178.21178.2 0.000122 24-Dec R.APLPDLYPFGTMR[166.11].G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1486.7518 1.64 16982 21178 2 1486.756711 744.3832 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3874.8 - 705841 - - - 3.3086 - 2.206 0.495 - 500.8 1 2 0 0.0049 13 0 0 0 7.01E+06 4.28E+06 - - - 4.7261 1 230117_WJC_METTL3_WT_vs_EV_F02.21181.21181.2 4.27E-05 13/20 K.LSDLDYMQFIR[166.11].L sp|P82933|RT09_HUMAN 1 1409.6889 1 16985 21181 2 1409.688568 705.8517 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.21 3875.1 - 588529 - - - -0.205 - 2.765 0.403 - 958 1 2 0 -0.0003 11 0 0 0 3.17E+06 3.19E+06 - - - 4.7688 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21182.21182.3 0.00502 Nov-44 R.LLALLDALASHK.A "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 1263.7551 1.33 16986 21182 3 1263.755312 422.259 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6.74 3875.2 - 522463 - - - 0.1891 - 2.376 0.307 - 216.4 1 2 0 0.0002 12 0 0 0 1.45E+06 1.09E+06 - - - 4.3615 0.9946 230117_WJC_METTL3_WT_vs_EV_F02.21183.21183.2 0.554 14-May R.SFTNQIIL.- "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIM4|A0A804HIM4_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 3 934.5124 - 16987 21183 2 934.513339 468.2635 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 5.24 3875.4 - 520516 - - - 1.023 - 1.138 0.222 - 42.7 2 2 0 0.001 8 0 0 0 - - - - - 0.9358 1 230117_WJC_METTL3_WT_vs_EV_F02.21184.21184.2 1.58E-06 26-Nov R.ILGIPVIVTEQYPK.G "sp|Q96CN7|ISOC1_HUMAN,tr|D6RGE2|D6RGE2_HUMAN" 2 1568.9178 1.22 16988 21184 2 1568.917522 785.4662 Isochorismatase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ISOC1 PE=1 SV=3 6 3875.5 - 416923 - - - -0.1651 - 2.093 0.597 - 289 1 2 0 -0.0003 14 0 0 0 1.84E+06 1.50E+06 - - - 5.3038 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.21185.21185.2 0.00011 14-Aug R.GFVFITFK[136.11].E "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 965.5466 0.85 16989 21185 2 965.546099 483.7806 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3875.6 - 346012 - - - -0.5085 - 1.706 0.484 - 282.2 1 2 0 -0.0005 8 0 0 0 7.10E+06 8.36E+06 - - - 4.2266 1 230117_WJC_METTL3_WT_vs_EV_F02.21186.21186.2 1.27E-10 15/36 R.LAESLLALSQQEELADLPK.D sp|Q9BVJ6|UT14A_HUMAN 1 2067.11 -1 16990 21186 2 2067.111306 1034.5623 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4 3875.8 - 271774 - - - 0.655 - 3.646 0.626 - 686.8 1 2 0 0.0014 19 0 0 0 0.00E+00 0.00E+00 - - - 6.8447 1 230117_WJC_METTL3_WT_vs_EV_F02.21190.21190.3 1.60E-06 21/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 16992 21190 3 1603.765494 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3876.3 - 6.42E+06 - - - 0.969 - 2.855 0.591 - 671.3 1 2 0 0.0016 12 0 0 0 4.31E+07 0.00E+00 - - - 8.0365 1 230117_WJC_METTL3_WT_vs_EV_F02.21191.21191.2 7.57E-07 16/26 R.VLLATLSIPITPER[166.11].T sp|Q14152|EIF3A_HUMAN 1 1531.9213 0.95 16993 21191 2 1531.92245 766.9679 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3876.4 - 1.87E+06 - - - 0.7507 - 3.068 0.501 - 815.2 1 2 0 0.0011 14 0 0 0 2.24E+07 2.36E+07 - - - 5.5542 1 230117_WJC_METTL3_WT_vs_EV_F02.21193.21193.2 0.0103 14/20 K.LSDLDYMQFIR.L sp|P82933|RT09_HUMAN 1 1399.6806 1 16995 21193 2 1399.679766 700.8476 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.21 3876.7 - 835397 - - - -0.5866 - 2.967 0.406 - 1119.4 1 2 0 -0.0008 11 0 0 0 3.17E+06 3.19E+06 - - - 4.9815 1 230117_WJC_METTL3_WT_vs_EV_F02.21194.21194.2 2.86E-05 14/24 R.LLSFSPEEFPTLK.A sp|Q5JSZ5|PRC2B_HUMAN 1 1506.797 1.55 16996 21194 2 1506.800415 754.4058 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3876.8 - 573973 - - - 2.2684 - 2.38 0.492 - 634.9 1 2 0 0.0034 13 0 0 0 5.95E+07 3.85E+07 - - - 4.8993 1 230117_WJC_METTL3_WT_vs_EV_F02.21195.21195.2 1.66E-07 13/26 R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 33.43 16997 21195 2 1581.810873 791.9109 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3876.9 - 467470 - - - 2.2942 - 2.846 0.637 - 409.6 1 2 0 0.0036 14 0 0 0 9.50E+06 2.84E+05 - - - 6.3694 1 230117_WJC_METTL3_WT_vs_EV_F02.21196.21196.2 2.77E-06 24-Dec R.ELPTAFDYVEFTR[166.11].S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1596.7699 1.32 16998 21196 2 1596.778221 799.3922 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.14 3877.1 - 403411 - - - 5.1836 - 2.484 0.531 - 590.3 1 2 0 0.0083 13 0 0 0 6.41E+06 4.85E+06 - - - 5.2956 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.21199.21199.2 0.000272 20-Sep R.VWIPDPDEVWR[166.11].S sp|Q9ULV0|MYO5B_HUMAN 1 1420.7015 -1 17001 21199 2 1420.698068 711.358 Unconventional myosin-Vb OS=Homo sapiens OX=9606 GN=MYO5B PE=1 SV=3 4.03 3877.5 - 200195 - - - -2.3953 - 1.678 0.431 - 258.3 1 2 0 -0.0034 11 0 0 0 0.00E+00 0.00E+00 - - - 3.6235 1 230117_WJC_METTL3_WT_vs_EV_F02.21203.21203.2 9.96E-09 28-Dec K.LLMSEDYFTQAMEVK[136.11].A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1811.8565 -1 17005 21203 2 1811.857203 906.9355 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.14 3878 - 110668 - - - 0.383 - 2.871 0.648 - 329.8 1 2 0 0.0007 15 0 0 0 0.00E+00 0.00E+00 - - - 6.4198 1 230117_WJC_METTL3_WT_vs_EV_F02.21206.21206.2 4.21E-09 28-Dec K.LLMSEDYFTQAMEVK.A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1803.8423 -1 17008 21206 2 1803.847793 902.9284 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.14 3878.4 - 81717.5 - - - 3.0402 - 2.683 0.639 - 296.3 1 2 0 0.0055 15 0 0 0 0.00E+00 0.00E+00 - - - 6.1854 0.994 230117_WJC_METTL3_WT_vs_EV_F02.21215.21215.2 8.18E-05 24-Dec R.LLSFSPEEFPTLK[136.11].A sp|Q5JSZ5|PRC2B_HUMAN 1 1514.8112 1.55 17016 21215 2 1514.820419 758.4129 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3879.5 - 1.17E+06 - - - 6.0879 - 2 0.364 - 321.1 1 2 0 0.0092 13 0 0 0 5.95E+07 3.85E+07 - - - 3.5056 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.21217.21217.2 0.00596 16-Sep K.TTPLLSFLK[136.11].N sp|Q9BZI7|REN3B_HUMAN 1 1026.6205 0.88 17018 21217 2 1026.62506 514.3175 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 8.41 3879.8 - 1.03E+06 - - - 4.4583 - 1.665 0.366 - 310.7 1 2 0 0.0046 9 0 0 0 2.30E+07 2.60E+07 - - - 3.2178 1 230117_WJC_METTL3_WT_vs_EV_F02.21224.21224.2 4.33E-05 14/24 R.ELYAFFGDSLATR.F sp|Q9Y6J9|TAF6L_HUMAN 1 1488.7249 0.94 17025 21224 2 1488.724168 745.3697 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4.37 3880.7 - 467035 - - - -0.4883 - 2.485 0.551 - 645.2 1 2 0 -0.0007 13 0 0 0 3.77E+06 4.02E+06 - - - 5.4467 1 230117_WJC_METTL3_WT_vs_EV_F02.21225.21225.2 7.17E-07 13/22 K.LTAYAMTIPFVR.Q "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1381.7428 1.14 17026 21225 2 1381.745306 691.8787 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 3880.8 - 456600 - - - 1.8187 - 2.427 0.544 - 817.1 1 2 0 0.0025 12 0 0 0 1.72E+06 1.51E+06 - - - 5.3911 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.21226.21226.2 0.00156 20-Nov K.NVPGLAILLSK.D sp|Q9BUL9|RPP25_HUMAN 1 1123.6965 1.48 17027 21226 2 1123.700258 562.8555 Ribonuclease P protein subunit p25 OS=Homo sapiens OX=9606 GN=RPP25 PE=1 SV=1 8.75 3880.9 - 432558 - - - 3.3488 - 1.805 0.426 - 298.3 1 2 0 0.0038 11 0 0 0 5.14E+06 3.48E+06 - - - 3.7839 0.9749 230117_WJC_METTL3_WT_vs_EV_F02.21227.21227.2 0.573 20-Jul K.AIGFVMVDAKK.E sp|O14958|CASQ2_HUMAN 1 1177.6529 1.88 17028 21227 2 1177.65202 589.8337 Calsequestrin-2 OS=Homo sapiens OX=9606 GN=CASQ2 PE=1 SV=2 8.64 3881.1 - 344739 - - - -0.7608 - 1.443 0.051 - 102.7 1 2 0 -0.0009 11 0 0 0 2.79E+06 1.48E+06 - - - 0.4095 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.21228.21228.2 0.0306 20-Nov K.NVPGLAILLSK[136.11].D sp|Q9BUL9|RPP25_HUMAN 1 1131.7107 1.46 17029 21228 2 1131.714872 566.8626 Ribonuclease P protein subunit p25 OS=Homo sapiens OX=9606 GN=RPP25 PE=1 SV=1 8.75 3881.2 - 337315 - - - 3.6909 - 1.813 0.355 - 309.5 1 2 0 0.0042 11 0 0 0 5.37E+06 3.67E+06 - - - 3.2713 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21236.21236.3 1.91E-05 Oct-52 R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 10.87 17036 21236 3 1581.810411 528.2764 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3882 - 55488.2 - - - 2.0021 - 2.394 0.49 - 200.6 1 2 0 0.0032 14 0 0 0 2.50E+06 2.30E+05 - - - 6.3221 1 230117_WJC_METTL3_WT_vs_EV_F02.21244.21244.2 0.000231 18-Dec R.LLEVYDQLFK.S "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1266.686 2.74 17042 21244 2 1266.689977 634.3503 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3882.9 - 1.27E+06 - - - 3.1476 - 2.297 0.446 - 493.7 1 2 0 0.004 10 0 0 0 2.27E+07 8.29E+06 - - - 4.6552 1 230117_WJC_METTL3_WT_vs_EV_F02.21246.21246.2 5.93E-07 26-Nov R.ILSVQGTEPLVLFK.E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1542.9021 1.38 17044 21246 2 1542.904797 772.4583 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3883 - 1.25E+06 - - - 1.7279 - 2.343 0.581 - 379.5 1 2 0 0.0027 14 0 0 0 2.11E+07 1.53E+07 - - - 5.4681 1 230117_WJC_METTL3_WT_vs_EV_F02.21249.21249.2 9.67E-09 22-Dec K.VMEETLSYLLGR.K "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN,tr|A0A5F9ZH78|A0A5F9ZH78_HUMAN" 3 1409.7225 12.06 17047 21249 2 1409.726214 705.8685 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 4.53 3883.2 - 601089 - - - 2.6686 - 2.388 0.646 - 531.8 1 2 0 0.0038 12 0 0 0 8.23E+06 6.83E+05 - - - 6.1015 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21250.21250.2 0.000763 16-Aug K.AFVPAILFK[136.11].D sp|Q9HAU5|RENT2_HUMAN 1 1012.6201 1.05 17048 21250 2 1012.620895 507.3173 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3883.2 - 589200 - - - 0.796 - 1.57 0.472 - 254.9 1 2 0 0.0008 9 0 0 0 9.75E+06 9.26E+06 - - - 3.8319 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.21251.21251.2 0.00195 20-Nov R.SIFTGLMIDPR.T sp|Q8IWA0|WDR75_HUMAN 1 1248.6536 1.56 17049 21251 2 1248.658763 625.3341 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 5.55 3883.3 - 448364 - - - 4.0996 - 1.962 0.352 - 316.8 1 2 0 0.0051 11 0 0 0 4.76E+06 3.05E+06 - - - 3.4625 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21254.21254.2 7.76E-05 26-Oct K.TGAAGAEALSLLLK.R "sp|Q9P2N6|KANL3_HUMAN,tr|C9J5A4|C9J5A4_HUMAN,tr|A0A590UJ53|A0A590UJ53_HUMAN" 3 1313.7555 2.99 17052 21254 2 1313.757613 657.885 KAT8 regulatory NSL complex subunit 3 OS=Homo sapiens OX=9606 GN=KANSL3 PE=1 SV=2 5.66 3883.7 - 256561 - - - 1.6335 - 2.203 0.434 - 289.9 1 2 0 0.0021 14 0 0 0 5.77E+06 1.93E+06 - - - 4.2279 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21260.21260.2 0.000408 16-Aug K.AFVPAILFK.D sp|Q9HAU5|RENT2_HUMAN 1 1004.6059 1.05 17056 21260 2 1004.606786 503.3102 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3884.3 - 504625 - - - 0.8929 - 1.563 0.407 - 202.7 1 2 0 0.0009 9 0 0 0 9.75E+06 9.26E+06 - - - 3.3389 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.21262.21262.2 0.0185 14-Jul R.LQWWDFTK.F "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1122.5498 2.09 17058 21262 2 1122.552637 562.2822 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 5.84 3884.6 - 210224 - - - 2.4997 - 1.455 0.323 - 158.4 1 2 0 0.0028 8 0 0 0 4.13E+06 1.98E+06 - - - 2.5568 0.9414 230117_WJC_METTL3_WT_vs_EV_F02.21264.21264.2 2.88 14-Jul R.LQWWDFTK[136.11].F "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1130.564 2.09 17060 21264 2 1130.565053 566.2893 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 5.84 3884.8 - 121593 - - - 0.904 - 1.075 0.009 - 116.1 1 2 0 0.001 8 0 0 0 4.13E+06 1.98E+06 - - - -0.6747 1 230117_WJC_METTL3_WT_vs_EV_F02.21272.21272.2 2.03E-05 13/26 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.44 17066 21272 2 1672.88234 837.4479 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3885.8 - 2.13E+07 - - - 0.6659 - 2.802 0.568 - 729 1 2 0 0.0011 14 0 0 0 6.00E+07 1.36E+08 - - - 5.8215 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21273.21273.2 9.98E-06 24-Nov R.FGQDIISPLLSVK.E "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V414|A0A7I2V414_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|J3KNG4|J3KNG4_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|G3V5F3|G3V5F3_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|A0A7I2V4B9|A0A7I2V4B9_HUMAN,tr|H0YJY1|H0YJY1_HUMAN,tr|H0YJS6|H0YJS6_HUMAN,tr|G3V363|G3V363_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2V5R9|A0A7I2V5R9_HUMAN,tr|G3V4I1|G3V4I1_HUMAN,tr|A0A7I2V3Y3|A0A7I2V3Y3_HUMAN" 24 1415.8024 1.49 17067 21273 2 1415.804546 708.9085 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 5.84 3885.8 - 1.31E+07 - - - 1.5037 - 2.003 0.346 - 291.4 1 2 0 0.0021 13 0 0 0 3.01E+07 2.02E+07 - - - 3.3787 1 230117_WJC_METTL3_WT_vs_EV_F02.21274.21274.3 2.95E-06 15/52 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.58 17068 21274 3 1672.884847 558.6344 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3885.9 - 1.03E+07 - - - 2.1645 - 2.577 0.523 - 417 1 2 0 0.0036 14 0 0 0 4.57E+07 7.92E+07 - - - 6.8856 1 230117_WJC_METTL3_WT_vs_EV_F02.21275.21275.2 4.22E-06 14/26 K.LFSLELVDESGEIR[166.11].A sp|P27694|RFA1_HUMAN 1 1615.8333 0.12 17069 21275 2 1615.832675 808.9239 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4 3885.9 - 8.06E+06 - - - -0.3701 - 2.935 0.507 - 878.4 1 2 0 -0.0006 14 0 0 0 7.38E+06 6.27E+07 - - - 5.4875 1 230117_WJC_METTL3_WT_vs_EV_F02.21276.21276.2 9.80E-07 19/26 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.44 17070 21276 2 1662.874521 832.4438 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3886 - 6.97E+06 - - - 0.9411 - 3.382 0.554 - 1687.1 1 2 0 0.0016 14 0 0 0 6.00E+07 1.36E+08 - - - 6.19 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.21278.21278.2 0.002 16-Sep R.WLGDLILSK[136.11].S "sp|O75530|EED_HUMAN,tr|A0A5F9ZI63|A0A5F9ZI63_HUMAN" 2 1051.6157 1.18 17072 21278 2 1051.617322 526.8151 Polycomb protein EED OS=Homo sapiens OX=9606 GN=EED PE=1 SV=2 5.84 3886.1 - 4.81E+06 - - - 1.512 - 1.681 0.302 - 234.2 1 2 0 0.0016 9 0 0 0 1.06E+07 9.05E+06 - - - 2.7737 1 230117_WJC_METTL3_WT_vs_EV_F02.21281.21281.2 0.00125 13/24 K.DAAIYLVTSLASK.A sp|P55060|XPO2_HUMAN 1 1350.7395 -1 17075 21281 2 1350.742523 676.377 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.83 3886.3 - 3.33E+06 - - - 2.2514 - 2.607 0.46 - 527.2 1 2 0 0.003 13 0 0 0 0.00E+00 0.00E+00 - - - 4.8969 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21282.21282.2 0.0271 18-Oct K.DAITQALFLR.E sp|Q9UNX4|WDR3_HUMAN 1 1146.6397 1.17 17076 21282 2 1146.641628 574.3271 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.84 3886.4 - 3.18E+06 - - - 1.6745 - 2.125 0.355 - 255.3 1 2 0 0.0019 10 0 0 0 3.05E+07 2.62E+07 - - - 3.7664 1 230117_WJC_METTL3_WT_vs_EV_F02.21283.21283.2 2.11E-05 18-Oct R.AEVWDLDMLR.S sp|Q6P2E9|EDC4_HUMAN 1 1246.6016 1.94 17077 21283 2 1246.602837 624.3081 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 4.03 3886.5 - 3.07E+06 - - - 0.9859 - 2.207 0.478 - 509.3 1 2 0 0.0012 10 0 0 0 6.10E+06 3.14E+06 - - - 4.7808 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21284.21284.2 0.000384 18-Oct K.DAITQALFLR[166.11].E sp|Q9UNX4|WDR3_HUMAN 1 1156.648 1.18 17078 21284 2 1156.649834 579.3313 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.84 3886.6 - 2.30E+06 - - - 1.6046 - 2.305 0.33 - 242.1 1 2 0 0.0019 10 0 0 0 3.04E+07 2.56E+07 - - - 3.8088 0.9943 230117_WJC_METTL3_WT_vs_EV_F02.21285.21285.2 0.376 16-Dec K.IPALDLLIK.L "sp|P78527|PRKDC_HUMAN,tr|F5GX40|F5GX40_HUMAN" 2 994.6427 -1 17079 21285 2 994.646191 498.3286 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 3886.8 - 1.84E+06 - - - 3.541 - 1.474 0.198 - 344.6 1 2 0 0.0035 9 0 0 0 0.00E+00 0.00E+00 - - - 1.6248 1 230117_WJC_METTL3_WT_vs_EV_F02.21287.21287.2 8.51E-08 13/30 R.LFVGNLPADITEDEFK.R sp|P23246|SFPQ_HUMAN 1 1806.904 1.01 17081 21287 2 1806.912236 904.4593 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3887 - 1.82E+06 - - - 4.5686 - 2.599 0.522 - 275.1 1 2 0 0.0083 16 0 0 0 3.43E+06 3.41E+06 - - - 5.2421 1 230117_WJC_METTL3_WT_vs_EV_F02.21289.21289.2 6.56E-10 15/30 R.LFVGNLPADITEDEFK[136.11].R sp|P23246|SFPQ_HUMAN 1 1814.9182 1.01 17083 21289 2 1814.920972 908.4664 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3887.3 - 1.69E+06 - - - 1.5378 - 3.123 0.601 - 423.8 1 2 0 0.0028 16 0 0 0 3.43E+06 3.41E+06 - - - 6.2789 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21290.21290.2 0.00184 13/20 R.LTGLLDLALEK.D sp|P04746|AMYP_HUMAN 1 1184.7016 1.54 17084 21290 2 1184.70327 593.3581 Pancreatic alpha-amylase OS=Homo sapiens OX=9606 GN=AMY2A PE=1 SV=2 4.37 3887.4 - 1.63E+06 - - - 1.3759 - 2.536 0.391 - 441 1 2 0 0.0016 11 0 0 0 6.64E+06 4.32E+06 - - - 4.4459 1 230117_WJC_METTL3_WT_vs_EV_F02.21294.21294.3 3.60E-09 21/52 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.58 17087 21294 3 1662.880741 555.2983 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3887.9 - 3.97E+06 - - - 4.6817 - 3.887 0.576 - 843.7 1 2 0 0.0078 14 0 0 0 4.61E+07 7.92E+07 - - - 8.5676 0.999 230117_WJC_METTL3_WT_vs_EV_F02.21295.21295.2 5.34E-05 13/22 R.GLFIIDPNGVIK.H sp|P30048|PRDX3_HUMAN 1 1284.7442 2.1 17088 21295 2 1284.748734 643.3794 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3888 - 2.86E+06 - - - 3.5493 - 2.371 0.303 - 426.3 1 2 0 0.0046 12 0 0 0 6.78E+07 3.22E+07 - - - 3.549 1 230117_WJC_METTL3_WT_vs_EV_F02.21297.21297.2 1.02E-07 13/22 R.LIMNYLVTEGFK.E sp|Q9NWU2|GID8_HUMAN 1 1426.753 1.03 17090 21297 2 1426.756252 714.3838 Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1 6 3888.3 - 1.48E+06 - - - 2.2625 - 2.522 0.606 - 502.2 1 2 0 0.0032 12 0 0 0 9.52E+06 9.28E+06 - - - 5.9499 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.21298.21298.2 0.00319 22-Nov R.GLFIIDPNGVIK[136.11].H sp|P30048|PRDX3_HUMAN 1 1292.7584 2.1 17091 21298 2 1292.762845 647.3865 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3888.4 - 1.44E+06 - - - 3.4585 - 2.095 0.245 - 295.6 1 2 0 0.0045 12 0 0 0 6.78E+07 3.22E+07 - - - 2.7951 1 230117_WJC_METTL3_WT_vs_EV_F02.21299.21299.2 4.04E-07 16/22 R.LIMNYLVTEGFK[136.11].E sp|Q9NWU2|GID8_HUMAN 1 1434.7672 1.02 17092 21299 2 1434.770144 718.3909 Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1 6 3888.5 - 1.41E+06 - - - 2.0352 - 2.579 0.585 - 667.7 1 2 0 0.0029 12 0 0 0 9.55E+06 9.37E+06 - - - 5.8537 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21300.21300.3 6.93E-06 Nov-40 R.SIIGMIDMFHK.Y "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1290.6464 1343.62 17093 21300 3 1290.649925 431.2228 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.46 3888.7 - 763594 - - - 2.6924 - 2.165 0.53 - 118.7 1 2 0 0.0035 11 0 0 0 1.40E+07 1.04E+04 - - - 6.6423 0.9896 230117_WJC_METTL3_WT_vs_EV_F02.21301.21301.2 0.0831 18-Sep K.FGVFNYSPFR[166.11].T "sp|Q9ULU4|PKCB1_HUMAN,tr|A0A087WVZ6|A0A087WVZ6_HUMAN,tr|H7C4X9|H7C4X9_HUMAN,tr|A0A087WYS3|A0A087WYS3_HUMAN,tr|A0A087WV57|A0A087WV57_HUMAN" 5 1242.6061 0.87 17094 21301 2 1242.612119 622.3103 Protein kinase C-binding protein 1 OS=Homo sapiens OX=9606 GN=ZMYND8 PE=1 SV=2 8.75 3888.8 - 940743 - - - 4.8326 - 1.445 0.245 - 214 1 2 0 0.006 10 0 0 0 2.32E+06 2.66E+06 - - - 1.8762 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21302.21302.2 0.00369 20-Nov R.LLEFELAQLTK[136.11].Q "sp|Q13464|ROCK1_HUMAN,tr|A0A0U1RQV4|A0A0U1RQV4_HUMAN" 2 1311.753 0.56 17095 21302 2 1311.754504 656.8838 Rho-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=ROCK1 PE=1 SV=1 4.53 3888.9 - 440050 - - - 1.1816 - 2.197 0.366 - 388.9 1 2 0 0.0015 11 0 0 0 5.01E+06 8.89E+06 - - - 3.8731 1 230117_WJC_METTL3_WT_vs_EV_F02.21303.21303.2 8.29E-06 14/26 R.YAIQLITAASLVC[160.03]R.K sp|Q9Y230|RUVB2_HUMAN 1 1577.8599 2.58 17096 21303 2 1577.864181 789.9373 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 8.22 3889.1 - 376328 - - - 2.6821 - 2.726 0.554 - 666.7 1 2 0 0.0042 14 0 0 0 4.23E+06 1.64E+06 - - - 5.6481 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.21308.21308.3 6.97E-07 Oct-48 K.DAAIYLVTSLASK[136.11].A sp|P55060|XPO2_HUMAN 1 1358.7537 6.09 17101 21308 3 1358.759848 453.9252 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.83 3889.7 - 265480 - - - 4.538 - 2.521 0.49 - 195.1 1 2 0 0.0062 13 0 0 0 9.83E+06 1.61E+06 - - - 6.5083 1 230117_WJC_METTL3_WT_vs_EV_F02.21311.21311.2 1.45E-09 18/32 R.LWVGGLGPNTSLAALAR[166.11].E sp|Q8NDT2|RB15B_HUMAN 1 1704.9551 -1 17104 21311 2 1704.964696 853.4848 Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3 9.75 3890.1 - 146601 - - - 5.6518 - 3.214 0.599 - 917.3 1 2 0 0.0096 17 0 0 0 0.00E+00 0.00E+00 - - - 6.3326 0.9025 230117_WJC_METTL3_WT_vs_EV_F02.21315.21315.2 3.25 22-Feb R.NFGASLLLPGLK[136.11].Q "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN,tr|D6RJC7|D6RJC7_HUMAN" 4 1236.7322 1.59 17107 21315 2 1236.733388 619.3734 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 8.75 3890.6 - 2.96E+06 - - - 0.9937 - 0.497 0.259 - 12.5 2 2 0 0.0012 12 0 0 0 5.03E+07 3.16E+07 - - - -1.0205 1 230117_WJC_METTL3_WT_vs_EV_F02.21319.21319.2 0.00061 20-Oct K.TITAYFGDLIR[166.11].R sp|Q96RS0|TGS1_HUMAN 1 1278.6848 1.6 17111 21319 2 1278.684717 640.3497 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 5.5 3890.8 - 1.01E+06 - - - -0.0321 - 2.019 0.538 - 281 1 2 0 0 11 0 0 0 1.62E+07 1.01E+07 - - - 4.9154 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21320.21320.2 4.29E-06 24-Dec K.DAAIYLVTSLASK[136.11].A sp|P55060|XPO2_HUMAN 1 1358.7537 -1 17112 21320 2 1358.755967 680.3841 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.83 3890.8 - 800634 - - - 1.6817 - 2.272 0.337 - 449 1 2 0 0.0023 13 0 0 0 0.00E+00 0.00E+00 - - - 3.6356 1 230117_WJC_METTL3_WT_vs_EV_F02.21322.21322.2 4.14E-07 14/26 K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.76 17114 21322 2 1651.933165 826.9731 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3890.9 - 360646 - - - 0.9189 - 2.619 0.565 - 582 1 2 0 0.0015 14 0 0 0 1.18E+08 1.56E+08 - - - 5.6297 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.21323.21323.2 0.0188 22-Jul K.SLPVSVPVWGFK[136.11].E sp|Q96B36|AKTS1_HUMAN 1 1322.7478 -1 17115 21323 2 1322.749921 662.3812 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 8.47 3891 - 360045 - - - 1.5967 - 1.279 0.34 - 78.6 2 2 0 0.0021 12 0 0 0 0.00E+00 0.00E+00 - - - 2.0646 1 230117_WJC_METTL3_WT_vs_EV_F02.21330.21330.2 5.23E-09 16/26 K.LYTLVTYVPVTTFK.N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1643.9174 0.76 17120 21330 2 1643.919122 822.966 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3891.7 - 6.10E+06 - - - 1.0189 - 2.764 0.631 - 869 1 2 0 0.0017 14 0 0 0 1.18E+08 1.56E+08 - - - 6.2523 1 230117_WJC_METTL3_WT_vs_EV_F02.21331.21331.2 2.30E-13 22/34 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.78 17121 21331 2 1936.01176 969.0131 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3891.8 - 4.17E+06 - - - 0.0883 - 4.308 0.668 - 1412.5 1 2 0 0.0002 18 0 0 0 3.08E+07 3.98E+07 - - - 7.5654 1 230117_WJC_METTL3_WT_vs_EV_F02.21332.21332.2 1.99E-15 21/34 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.78 17122 21332 2 1926.004277 964.0089 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3892 - 2.95E+06 - - - 0.4974 - 4.297 0.696 - 1330.9 1 2 0 0.001 18 0 0 0 3.08E+07 3.98E+07 - - - 7.7657 1 230117_WJC_METTL3_WT_vs_EV_F02.21333.21333.2 0.0128 20-Dec K.LLTQYILNLGK.Y sp|O00203|AP3B1_HUMAN 1 1274.7598 -1 17123 21333 2 1274.763545 638.3872 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 8.59 3892.1 - 2.93E+06 - - - 2.919 - 2.33 0.47 - 488.7 1 2 0 0.0037 11 0 0 0 0.00E+00 0.00E+00 - - - 4.7995 1 230117_WJC_METTL3_WT_vs_EV_F02.21335.21335.2 1.72E-05 13/24 K.NVLIVEDIIDTGK.T sp|P00492|HPRT_HUMAN 1 1427.7872 1.95 17125 21335 2 1427.788903 714.9009 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.03 3892.4 - 2.48E+06 - - - 1.2201 - 2.652 0.544 - 528.7 1 2 0 0.0017 13 0 0 0 1.30E+07 6.65E+06 - - - 5.5616 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21336.21336.3 0.0123 19/52 K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.68 17126 21336 3 1651.937411 551.6512 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3892.5 - 1.74E+06 - - - 3.4892 - 2.645 0.312 - 298.4 1 2 0 0.0058 14 0 0 0 1.44E+07 2.11E+07 - - - 4.6018 1 230117_WJC_METTL3_WT_vs_EV_F02.21337.21337.2 5.76E-05 14/24 R.TFLVDPNLDLSIR.E "sp|Q9BSJ2|GCP2_HUMAN,tr|A0A804HJH7|A0A804HJH7_HUMAN,tr|F2Z2B9|F2Z2B9_HUMAN,tr|A0A804HK74|A0A804HK74_HUMAN,tr|A0A804HL95|A0A804HL95_HUMAN,tr|A0A804HJ08|A0A804HJ08_HUMAN,tr|A0A804HJQ4|A0A804HJQ4_HUMAN,tr|A0A804HJS9|A0A804HJS9_HUMAN,tr|A0A804HI27|A0A804HI27_HUMAN" 9 1501.814 -1 17127 21337 2 1501.815652 751.9143 Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2 4.21 3892.6 - 1.24E+06 - - - 1.0707 - 2.392 0.519 - 617.4 1 2 0 0.0016 13 0 0 0 0.00E+00 0.00E+00 - - - 5.1122 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21339.21339.2 4.82E-06 24-Dec K.NVLIVEDIIDTGK[136.11].T sp|P00492|HPRT_HUMAN 1 1435.8014 1.95 17129 21339 2 1435.80193 718.908 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.03 3892.9 - 1.01E+06 - - - 0.3963 - 2.152 0.326 - 356.4 1 2 0 0.0006 13 0 0 0 1.30E+07 6.65E+06 - - - 3.4156 0.9889 230117_WJC_METTL3_WT_vs_EV_F02.21340.21340.2 0.0554 20-Oct K.VLAISDLVIYR.T "sp|Q9HBF4|ZFYV1_HUMAN,tr|G3V5N8|G3V5N8_HUMAN" 2 1260.7442 -1 17130 21340 2 1260.752917 631.3794 Zinc finger FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZFYVE1 PE=1 SV=1 5.81 3893 - 993110 - - - 6.9348 - 2.122 0.314 - 309.9 1 2 0 0.0087 11 0 0 0 0.00E+00 0.00E+00 - - - 3.3928 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21341.21341.2 6.43E-05 24-Sep K.NPLPVTLTNVVFR.L "sp|P22735|TGM1_HUMAN,tr|H0YMQ8|H0YMQ8_HUMAN" 2 1468.8402 -1 17131 21341 2 1468.842675 735.4274 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 9.75 3893.1 - 873909 - - - 1.6857 - 2.079 0.477 - 231.1 1 2 0 0.0025 13 0 0 0 0.00E+00 0.00E+00 - - - 4.4418 0.9535 230117_WJC_METTL3_WT_vs_EV_F02.21342.21342.2 0.000369 22-Nov S.ILTIEDGIFEVK.S "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1375.7599 30.44 17132 21342 2 1375.763477 688.8872 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3893.3 - 808963 - - - 2.6124 - 2.053 0.346 - 399.3 1 1 0 0.0036 12 0 0 0 4.95E+06 1.63E+05 - - - 3.488 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21351.21351.2 0.000296 22-Sep R.LFQVEYAIEAIK.L sp|P28066|PSA5_HUMAN 1 1422.7759 2.01 17140 21351 2 1422.7787 712.3952 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 4.53 3894.3 - 1.66E+07 - - - 1.9905 - 1.966 0.481 - 257.1 1 2 0 0.0028 12 0 0 0 3.16E+07 1.57E+07 - - - 4.3715 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21352.21352.3 3.68E-06 Oct-68 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.81 17141 21352 3 1936.0146 646.3445 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3894.4 - 1.33E+07 - - - 1.5553 - 2.086 0.489 - 112.6 1 2 0 0.003 18 0 0 0 2.67E+07 3.30E+07 - - - 5.8219 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21353.21353.3 1.15E-09 18/68 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.81 17142 21353 3 1926.009904 643.0084 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3894.4 - 1.13E+07 - - - 3.419 - 2.791 0.547 - 276.1 1 2 0 0.0066 18 0 0 0 2.67E+07 3.30E+07 - - - 7.1925 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21356.21356.2 0.00779 16-Sep K.SLDIYSFIK.E "sp|Q9NR50|EI2BG_HUMAN,tr|H0Y580|H0Y580_HUMAN" 2 1084.5805 0.67 17145 21356 2 1084.581755 543.2975 Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens OX=9606 GN=EIF2B3 PE=1 SV=1 5.55 3894.6 - 4.40E+06 - - - 1.1922 - 1.884 0.317 - 227.8 1 2 0 0.0013 9 0 0 0 7.52E+06 1.12E+07 - - - 3.2144 1 230117_WJC_METTL3_WT_vs_EV_F02.21357.21357.2 0.000794 13/20 R.EALDVLGAVLK.A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1126.6598 1.36 17146 21357 2 1126.662641 564.3372 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3894.7 - 3.77E+06 - - - 2.5438 - 2.437 0.53 - 591.7 1 2 0 0.0029 11 0 0 0 3.33E+07 2.45E+07 - - - 5.3644 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21358.21358.2 0.000101 20-Sep K.TLC[160.03]PLC[160.03]FSILK.G "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1350.704 -1 17147 21358 2 1350.705847 676.3593 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 7.74 3894.8 - 3.10E+06 - - - 1.3926 - 1.942 0.46 - 212.2 1 2 0 0.0019 11 0 0 0 0.00E+00 0.00E+00 - - - 4.2335 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21359.21359.2 1.34E-05 20-Oct R.EALDVLGAVLK[136.11].A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1134.674 1.36 17148 21359 2 1134.676091 568.3443 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3894.9 - 3.05E+06 - - - 1.8649 - 2.145 0.461 - 266.7 1 2 0 0.0021 11 0 0 0 3.33E+07 2.45E+07 - - - 4.5098 1 230117_WJC_METTL3_WT_vs_EV_F02.21360.21360.2 3.53E-08 18-Dec R.VYNALVAFIR.A sp|Q9BW92|SYTM_HUMAN 1 1164.6655 0.97 17149 21360 2 1164.668266 583.34 "Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1" 8.72 3894.9 - 2.52E+06 - - - 2.35 - 2.342 0.548 - 583.9 1 2 0 0.0027 10 0 0 0 4.27E+06 4.41E+06 - - - 5.4631 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.21363.21363.2 0.0289 18-Jul R.GVVLFPWQAR.L sp|Q9Y2S7|PDIP2_HUMAN 1 1171.6502 1.72 17152 21363 2 1171.652029 586.8324 Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1 9.75 3895.2 - 1.87E+06 - - - 1.5491 - 1.361 0.257 - 135.1 1 2 0 0.0018 10 0 0 0 4.61E+06 2.67E+06 - - - 1.799 1 230117_WJC_METTL3_WT_vs_EV_F02.21365.21365.2 4.71E-06 14/28 R.TIAIIAEGIPEALTR.K sp|P53396|ACLY_HUMAN 1 1566.8981 -1 17154 21365 2 1566.902911 784.4563 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.53 3895.5 - 1.48E+06 - - - 3.0653 - 2.827 0.497 - 704.5 1 2 0 0.0048 15 0 0 0 0.00E+00 0.00E+00 - - - 5.2653 1 230117_WJC_METTL3_WT_vs_EV_F02.21366.21366.2 3.37E-07 16/24 R.VLGATLLPDLIQK[136.11].V "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN,tr|H0YDG0|H0YDG0_HUMAN" 5 1387.853 1.59 17155 21366 2 1387.856304 694.9338 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.81 3895.6 - 1.47E+06 - - - 2.3792 - 2.882 0.592 - 890.8 1 2 0 0.0033 13 0 0 0 4.80E+06 3.02E+06 - - - 6.1291 0.989 230117_WJC_METTL3_WT_vs_EV_F02.21367.21367.2 0.107 20-Oct R.NLIIEAVTNLR[166.11].L "sp|Q12789|TF3C1_HUMAN,tr|H3BU37|H3BU37_HUMAN" 2 1264.7379 -1 17156 21367 2 1264.742182 633.3762 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 6 3895.8 - 1.35E+06 - - - 3.4205 - 2.009 0.032 - 437.1 2 2 0 0.0043 11 0 0 0 0.00E+00 0.00E+00 - - - 1.0288 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.21368.21368.2 0.00031 28-Nov R.TIAIIAEGIPEALTR[166.11].K sp|P53396|ACLY_HUMAN 1 1576.9064 -1 17157 21368 2 1576.908105 789.4605 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.53 3895.9 - 1.10E+06 - - - 1.0952 - 1.681 0.325 - 237.8 1 2 0 0.0017 15 0 0 0 0.00E+00 0.00E+00 - - - 2.7178 0.9967 230117_WJC_METTL3_WT_vs_EV_F02.21373.21373.2 1.16 20-Jun K.IALLNVELELK.A sp|Q99832|TCPH_HUMAN 1 1253.7595 12.53 17161 21373 2 1253.759388 627.887 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.53 3896.3 - 1.12E+06 - - - -0.0806 - 1.555 0.212 - 120 2 2 0 -0.0001 11 0 0 0 4.49E+07 3.58E+06 - - - 1.6666 0.9022 230117_WJC_METTL3_WT_vs_EV_F02.21380.21380.2 1.49 18-May R.GVVLFPWQAR[166.11].L sp|Q9Y2S7|PDIP2_HUMAN 1 1181.6585 1.71 17168 21380 2 1181.65886 591.8365 Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1 9.75 3896.8 - 100859 - - - 0.3182 - 0.843 0.073 - 57.6 1 2 0 0.0004 10 0 0 0 4.58E+06 2.67E+06 - - - -0.8967 1 230117_WJC_METTL3_WT_vs_EV_F02.21382.21382.2 3.30E-07 13/36 R.LFVSDGVPGC[160.03]LPVLAAAGR.A "sp|P56192|SYMC_HUMAN,tr|F8W0S4|F8W0S4_HUMAN,tr|F8W0M7|F8W0M7_HUMAN,tr|F8VPL7|F8VPL7_HUMAN,tr|F5H2V6|F5H2V6_HUMAN,tr|F8VS26|F8VS26_HUMAN,tr|F8VZZ9|F8VZZ9_HUMAN" 7 1898.0084 -1 17170 21382 2 1898.01518 950.0115 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 5.83 3897.1 - 0 - - - 3.5701 - 2.403 0.563 - 164.4 1 2 0 0.0068 19 0 0 0 0.00E+00 0.00E+00 - - - 5.3526 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.21392.21392.2 0.0019 18-Sep K.C[160.03]MQLTDFILK[136.11].F "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1275.6447 0.74 17178 21392 2 1275.6497 638.8296 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.83 3898.2 - 700888 - - - 3.9462 - 1.985 0.462 - 252 1 2 0 0.005 10 0 0 0 1.04E+07 1.40E+07 - - - 4.3655 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21393.21393.2 0.00115 13/18 K.LLEPVLLLGK[136.11].E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1101.7253 1.68 17179 21393 2 1101.726111 551.8699 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3898.3 - 703269 - - - 0.7515 - 2.433 0.338 - 566 1 2 0 0.0008 10 0 0 0 4.39E+08 2.61E+08 - - - 4.019 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21394.21394.2 0.00126 18-Aug K.C[160.03]MQLTDFILK.F "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1267.6305 0.74 17180 21394 2 1267.631402 634.8225 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.83 3898.3 - 682694 - - - 0.7384 - 1.74 0.434 - 211.4 1 2 0 0.0009 10 0 0 0 1.04E+07 1.40E+07 - - - 3.7923 1 230117_WJC_METTL3_WT_vs_EV_F02.21395.21395.2 4.69E-07 24-Nov K.YVFLDPLAGAVTK.T "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|A8MWX3|WASH4_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 6 1392.7653 2.28 17181 21395 2 1392.767186 697.3899 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 5.83 3898.4 - 616799 - - - 1.352 - 2.191 0.564 - 309.3 1 2 0 0.0019 13 0 0 0 1.12E+07 4.93E+06 - - - 5.2192 1 230117_WJC_METTL3_WT_vs_EV_F02.21397.21397.2 5.65E-07 14/24 K.YVFLDPLAGAVTK[136.11].T "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|A8MWX3|WASH4_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 6 1400.7795 2.28 17183 21397 2 1400.782139 701.397 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 5.83 3898.5 - 301866 - - - 1.8818 - 2.578 0.6 - 564.4 1 2 0 0.0026 13 0 0 0 1.12E+07 4.93E+06 - - - 5.9023 0.9929 230117_WJC_METTL3_WT_vs_EV_F02.21400.21400.2 0.283 26-Mar R.VIVSDVQESFIWVR[166.11].Y sp|Q15393|SF3B3_HUMAN 1 1685.9016 3.78 17186 21400 2 1685.90676 843.9581 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3898.7 - 257530 - - - 3.0447 - 1.194 0.282 - 16.2 7 2 0 0.0051 14 0 0 0 2.02E+07 5.33E+06 - - - 1.1897 1 230117_WJC_METTL3_WT_vs_EV_F02.21406.21406.2 9.43E-05 20-Nov K.DPWDAVLLEER[166.11].S "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 1351.6648 -1 17192 21406 2 1351.65916 676.8397 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 3.92 3899.1 - 201751 - - - -4.1364 - 2.462 0.54 - 504.4 1 2 0 -0.0056 11 0 0 0 0.00E+00 0.00E+00 - - - 5.465 0.9868 230117_WJC_METTL3_WT_vs_EV_F02.21410.21410.2 0.0912 14-Sep R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 16.93 17195 21410 2 1000.563465 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3899.6 - 47083.1 - - - 4.1297 - 1.811 0.058 - 241 1 2 0 0.0041 8 0 0 0 8.44E+06 4.98E+05 - - - 1.2592 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.21412.21412.2 6.73E-05 24-Oct R.LDPETLESLGLIK[136.11].Q "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 1434.8061 1.59 17196 21412 2 1434.810311 718.4103 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 4.14 3899.8 - 558798 - - - 2.9265 - 1.994 0.425 - 292.4 1 2 0 0.0042 13 0 0 0 6.62E+06 4.18E+06 - - - 3.95 1 230117_WJC_METTL3_WT_vs_EV_F02.21413.21413.2 2.73E-07 14/26 R.VIVSDVQESFIWVR[166.11].Y sp|Q15393|SF3B3_HUMAN 1 1685.9016 3.78 17197 21413 2 1685.903241 843.9581 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3899.9 - 719882 - - - 0.9574 - 2.961 0.541 - 578.4 1 2 0 0.0016 14 0 0 0 2.02E+07 5.33E+06 - - - 5.7604 1 230117_WJC_METTL3_WT_vs_EV_F02.21414.21414.3 1.53E-07 19/52 K.LPLFPEPLHVFAPR.A "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|K7ENW7|K7ENW7_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 7 1631.9188 0.83 17198 21414 3 1631.921039 544.9802 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 6.75 3900 - 756450 - - - 1.3818 - 3.488 0.497 - 636.4 1 2 0 0.0023 14 0 0 0 4.82E+06 5.81E+06 - - - 7.4006 1 230117_WJC_METTL3_WT_vs_EV_F02.21417.21417.2 2.37E-10 15/32 R.VLALSVETDYTFPLAEK.V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN" 5 1894.9928 1 17201 21417 2 1894.994407 948.5037 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 4.14 3900.3 - 491660 - - - 0.8501 - 3.246 0.629 - 549.5 1 2 0 0.0016 17 0 0 0 2.34E+06 2.35E+06 - - - 6.581 1 230117_WJC_METTL3_WT_vs_EV_F02.21419.21419.2 2.87E-13 18/32 R.VLALSVETDYTFPLAEK[136.11].V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN" 5 1903.007 1.09 17203 21419 2 1903.010304 952.5108 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 4.14 3900.6 - 320353 - - - 1.7383 - 4.413 0.691 - 826.4 1 2 0 0.0033 17 0 0 0 2.30E+06 2.11E+06 - - - 7.7935 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.21420.21420.2 0.00235 18-Jul K.EYLPFLNTLK[136.11].K "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN" 12 1244.6896 -1 17204 21420 2 1244.693205 623.3521 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 6.1 3900.7 - 311503 - - - 2.8762 - 1.583 0.3 - 109.9 1 2 0 0.0036 10 0 0 0 0.00E+00 0.00E+00 - - - 2.5378 0.8927 230117_WJC_METTL3_WT_vs_EV_F02.21421.21421.2 0.0546 18-Aug D.SGGPLIVHK[136.11]R[166.11].S "sp|P00751|CFAB_HUMAN,tr|H7C5H1|H7C5H1_HUMAN,tr|H7C526|H7C526_HUMAN,tr|E7ETN3|E7ETN3_HUMAN,tr|B4E1Z4|B4E1Z4_HUMAN" 5 1080.6523 0.86 17205 21421 2 1080.654718 541.3334 Complement factor B OS=Homo sapiens OX=9606 GN=CFB PE=1 SV=2 11 3900.8 - 309142 - - - 2.2542 - 1.51 0.268 - 101.4 1 1 0 0.0024 10 0 0 0 1.22E+06 1.41E+06 - - - 2.17 1 230117_WJC_METTL3_WT_vs_EV_F02.21422.21422.2 8.39E-05 18-Nov K.QEVPIIIVFR.A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1212.723 1.35 17206 21422 2 1212.725831 607.3688 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3900.9 - 307334 - - - 2.2981 - 2.014 0.499 - 450.7 1 2 0 0.0028 10 0 0 0 1.05E+07 7.80E+06 - - - 4.68 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.21424.21424.2 0.0174 14-Jul K.SFDLLILK[136.11].E "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 955.5834 0.92 17208 21424 2 955.583344 478.799 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 5.55 3901.2 - 227987 - - - -0.0262 - 1.504 0.272 - 136.7 1 2 0 0 8 0 0 0 1.96E+06 2.13E+06 - - - 2.2809 1 230117_WJC_METTL3_WT_vs_EV_F02.21425.21425.2 2.08E-09 20-Dec K.DPWDAVLLEER[166.11].S "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 1351.6648 -1 17209 21425 2 1352.664495 676.8397 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 3.92 3901.3 - 218881 - - - 739.639 - 2.608 0.554 - 650.1 1 2 0 0.9997 11 0 0 0 0.00E+00 0.00E+00 - - - 5.4121 1 230117_WJC_METTL3_WT_vs_EV_F02.21426.21426.2 1.41E-06 18-Oct F.TMFLTMFGEK.L "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 1203.5668 1.33 17210 21426 2 1203.565784 602.7907 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 5.66 3901.4 - 202443 - - - -0.8467 - 1.928 0.515 - 229.7 1 1 0 -0.001 10 0 0 0 7.91E+05 5.94E+05 - - - 4.6769 1 230117_WJC_METTL3_WT_vs_EV_F02.21427.21427.2 6.26E-07 20-Dec R.FVASYLEYAFR.K sp|Q96GM8|TOE1_HUMAN 1 1364.6765 1.89 17211 21427 2 1364.676915 683.3455 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 6 3901.6 - 135549 - - - 0.3129 - 2.239 0.519 - 460.4 1 2 0 0.0004 11 0 0 0 1.43E+06 7.57E+05 - - - 5.0547 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21430.21430.2 2.08E-05 28-Nov K.ILDVASLEVLNEVNR[166.11].R sp|Q92616|GCN1_HUMAN 1 1692.9286 -1 17214 21430 2 1692.930025 847.4716 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.14 3902 - 63999.8 - - - 0.8595 - 2.372 0.462 - 361.9 1 2 0 0.0015 15 0 0 0 0.00E+00 0.00E+00 - - - 4.5764 1 230117_WJC_METTL3_WT_vs_EV_F02.21435.21435.2 0.000791 16-Nov R.DIDAFWLQR.Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1162.5771 1.56 17218 21435 2 1162.580479 582.2958 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3902.6 - 2.57E+06 - - - 2.8996 - 2.062 0.469 - 423.7 1 2 0 0.0034 9 0 0 0 1.54E+07 9.84E+06 - - - 4.5976 1 230117_WJC_METTL3_WT_vs_EV_F02.21437.21437.2 0.000139 18-Dec K.QEVPIIIVFR[166.11].A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1222.7313 1.35 17220 21437 2 1222.735379 612.3729 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3902.9 - 992664 - - - 3.3245 - 2.212 0.536 - 578.3 1 2 0 0.0041 10 0 0 0 1.05E+07 7.80E+06 - - - 5.2146 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21438.21438.2 0.000445 14-Aug K.NFAFLEFR.S "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1042.5236 1.18 17221 21438 2 1042.52616 522.2691 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3903 - 909015 - - - 2.4402 - 1.713 0.437 - 285 1 2 0 0.0025 8 0 0 0 1.19E+07 1.01E+07 - - - 3.8912 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.21439.21439.2 0.000184 14-Oct K.SFDLLILK.E "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 947.5692 0.92 17222 21439 2 947.572252 474.7919 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 5.55 3903.1 - 776765 - - - 3.2536 - 1.897 0.45 - 286.8 1 2 0 0.0031 8 0 0 0 1.96E+06 2.13E+06 - - - 4.2948 1 230117_WJC_METTL3_WT_vs_EV_F02.21440.21440.2 0.00124 18-Oct K.LFEISDIVIK[136.11].D sp|Q9NSD9|SYFB_HUMAN 1 1183.6944 -1 17223 21440 2 1183.69827 592.8545 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 4.37 3903.3 - 501379 - - - 3.2897 - 2.046 0.51 - 212.5 1 2 0 0.0039 10 0 0 0 0.00E+00 0.00E+00 - - - 4.8049 0.901 230117_WJC_METTL3_WT_vs_EV_F02.21441.21441.2 0.804 14-Jul N.GVSQLIQR[166.11].E sp|P48201|AT5G3_HUMAN 1 909.5271 0.88 17224 21441 2 909.52919 455.7708 "ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1" 9.75 3903.4 - 433857 - - - 2.2594 - 1.613 0.241 - 216.2 1 1 0 0.0021 8 0 0 0 9.19E+07 1.04E+08 - - - 2.2623 0.9931 230117_WJC_METTL3_WT_vs_EV_F02.21443.21443.2 0.12 16-Jun R.MDPAWHPWL.- "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1151.5222 - 17226 21443 2 1151.524822 576.7684 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 5.06 3903.7 - 366840 - - - 2.2457 - 1.061 0.226 - 67.9 1 2 0 0.0026 9 0 0 0 - - - - - 0.8807 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21444.21444.2 0.000308 22-Sep R.EVAAGYLVPLLR.S sp|Q13395|TARB1_HUMAN 1 1299.7551 1.66 17227 21444 2 1299.75906 650.8848 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6.1 3903.8 - 358698 - - - 3.0675 - 2.021 0.454 - 313.2 1 2 0 0.004 12 0 0 0 1.52E+06 9.15E+05 - - - 4.2443 1 230117_WJC_METTL3_WT_vs_EV_F02.21448.21448.2 3.53E-07 26-Dec R.VIVSDVQESFIWVR.Y sp|Q15393|SF3B3_HUMAN 1 1675.8934 1.21 17231 21448 2 1675.896889 838.954 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3904.3 - 341791 - - - 2.1075 - 2.611 0.597 - 365.1 1 2 0 0.0035 14 0 0 0 5.60E+06 4.61E+06 - - - 5.8577 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21449.21449.2 0.000656 22-Aug R.LGAPGFAWEPFR.G "sp|Q9HCM7|FBSL_HUMAN,tr|A0A3B3IRR3|A0A3B3IRR3_HUMAN,tr|A0A7P0Z485|A0A7P0Z485_HUMAN" 3 1346.6772 2.12 17232 21449 2 1346.679522 674.3459 Fibrosin-1-like protein OS=Homo sapiens OX=9606 GN=FBRSL1 PE=1 SV=4 6 3904.4 - 326882 - - - 1.7562 - 1.631 0.41 - 163.1 1 2 0 0.0024 12 0 0 0 1.82E+06 8.59E+05 - - - 3.3557 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21454.21454.2 0.000463 22-Oct R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 369.1 17236 21454 2 1603.767661 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3905 - 9.76E+06 - - - 2.3202 - 1.937 0.505 - 314.8 1 2 0 0.0037 12 0 0 0 1.50E+08 4.06E+05 - - - 4.5093 0.8654 230117_WJC_METTL3_WT_vs_EV_F02.21456.21456.2 0.945 14-Jul N.GVSQLIQR.E sp|P48201|AT5G3_HUMAN 1 899.5189 0.88 17238 21456 2 899.519289 450.7667 "ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1" 9.75 3905.2 - 3.60E+06 - - - 0.4714 - 1.43 0.24 - 213.2 1 1 0 0.0004 8 0 0 0 9.19E+07 1.04E+08 - - - 1.8922 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21457.21457.2 0.000532 16-Oct R.DIDAFWLQR[166.11].Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1172.5854 1.6 17239 21457 2 1172.58625 587.3 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3905.3 - 2.96E+06 - - - 0.7437 - 1.99 0.398 - 342.7 1 2 0 0.0009 9 0 0 0 1.53E+07 9.56E+06 - - - 3.9712 1 230117_WJC_METTL3_WT_vs_EV_F02.21459.21459.2 0.000196 14-Oct K.NFAFLEFR[166.11].S "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1052.5319 1.2 17241 21459 2 1052.533279 527.2732 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3905.5 - 1.53E+06 - - - 1.3235 - 1.77 0.523 - 520.1 1 2 0 0.0014 8 0 0 0 1.19E+07 9.92E+06 - - - 4.6255 1 230117_WJC_METTL3_WT_vs_EV_F02.21462.21462.2 3.53E-07 13/24 K.VFSATLGLVDIVK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1360.7966 1.11 17244 21462 2 1360.797683 681.4056 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3905.9 - 481051 - - - 0.7937 - 2.564 0.557 - 483.1 1 2 0 0.0011 13 0 0 0 9.78E+07 8.80E+07 - - - 5.5712 1 230117_WJC_METTL3_WT_vs_EV_F02.21463.21463.2 1.92E-08 14/24 K.TVQTAVFLYSLYK.E "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 1531.8286 1.23 17245 21463 2 1531.831012 766.9216 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.17 3906 - 451404 - - - 1.5537 - 2.783 0.588 - 494.9 1 2 0 0.0024 13 0 0 0 5.01E+06 4.08E+06 - - - 6.0101 1 230117_WJC_METTL3_WT_vs_EV_F02.21464.21464.2 5.12E-07 14/22 K.VVYTSLQWASLQ.- "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN" 2 1393.7242 - 17246 21464 2 1393.720156 697.8694 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 5.49 3906.1 - 400856 - - - -2.8772 - 2.608 0.54 - 425.2 1 2 0 -0.004 12 0 0 0 - - - - - 5.5504 1 230117_WJC_METTL3_WT_vs_EV_F02.21465.21465.2 8.32E-07 16/24 K.VFSATLGLVDIVK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1368.8108 1.11 17247 21465 2 1368.812563 685.4127 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3906.3 - 356919 - - - 1.2858 - 2.574 0.547 - 661.5 1 2 0 0.0018 13 0 0 0 9.78E+07 8.80E+07 - - - 5.5071 1 230117_WJC_METTL3_WT_vs_EV_F02.21469.21469.2 2.02E-07 28-Nov K.IVFVPGC[160.03]SIPLTIVK.S sp|P54136|SYRC_HUMAN 1 1641.9528 1.6 17251 21469 2 1641.955833 821.9837 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3906.8 - 197847 - - - 1.8551 - 2.22 0.602 - 238.2 1 2 0 0.003 15 0 0 0 2.37E+07 1.48E+07 - - - 5.4471 1 230117_WJC_METTL3_WT_vs_EV_F02.21472.21472.2 3.50E-05 13/22 K.IILDLISESPIK.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1339.7963 1.14 17254 21472 2 1339.797183 670.9054 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3907.2 - 154684 - - - 0.6822 - 2.763 0.521 - 529.1 1 2 0 0.0009 12 0 0 0 3.21E+08 2.82E+08 - - - 5.5629 1 230117_WJC_METTL3_WT_vs_EV_F02.21484.21484.2 2.72E-07 14/24 K.LEVAPISDIIAIK.S "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 6 1380.8228 3.32 17263 21484 2 1380.821221 691.4187 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 4.37 3908.5 - 5.62E+06 - - - -1.1566 - 2.652 0.494 - 417.9 1 2 0 -0.0016 13 0 0 0 3.75E+07 1.13E+07 - - - 5.1924 1 230117_WJC_METTL3_WT_vs_EV_F02.21485.21485.2 0.000306 14/22 K.IILDLISESPIK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1347.8105 1.14 17264 21485 2 1347.809235 674.9125 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3908.6 - 5.85E+06 - - - -0.9156 - 2.708 0.487 - 610.1 1 2 0 -0.0012 12 0 0 0 3.20E+08 2.82E+08 - - - 5.2588 1 230117_WJC_METTL3_WT_vs_EV_F02.21486.21486.2 3.70E-06 28-Dec K.IVFVPGC[160.03]SIPLTIVK[136.11].S sp|P54136|SYRC_HUMAN 1 1649.967 1.6 17265 21486 2 1649.965259 825.9908 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3908.7 - 1.41E+06 - - - -1.0473 - 2.361 0.529 - 339.9 1 2 0 -0.0017 15 0 0 0 2.37E+07 1.48E+07 - - - 5.0598 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.21487.21487.2 1.31 16-Aug R.LLPDFLLER[166.11].R "sp|Q12894|IFRD2_HUMAN,tr|H7C444|H7C444_HUMAN,tr|A0A0R4J2F6|A0A0R4J2F6_HUMAN" 3 1124.6469 -1 17266 21487 2 1124.648975 563.3307 Interferon-related developmental regulator 2 OS=Homo sapiens OX=9606 GN=IFRD2 PE=1 SV=3 4.37 3908.8 - 1.01E+06 - - - 1.8308 - 1.832 0.193 - 113.2 3 2 0 0.0021 9 0 0 0 0.00E+00 0.00E+00 - - - 2.0042 1 230117_WJC_METTL3_WT_vs_EV_F02.21488.21488.3 2.34E-06 13/48 R.LLGNTFVALSDLR.C "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1417.7929 -1 17267 21488 3 1417.794192 473.6049 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.84 3909 - 940069 - - - 0.9007 - 2.421 0.508 - 228.2 1 2 0 0.0013 13 0 0 0 0.00E+00 0.00E+00 - - - 6.6006 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21491.21491.2 0.00437 13/24 K.LDNLLLDTEGFVK.L sp|Q16513|PKN2_HUMAN 1 1475.7872 -1 17270 21491 2 1475.786877 738.9009 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.03 3909.4 - 611377 - - - -0.1924 - 2.349 0.367 - 398.5 1 2 0 -0.0003 13 0 0 0 0.00E+00 0.00E+00 - - - 3.9434 1 230117_WJC_METTL3_WT_vs_EV_F02.21492.21492.2 6.51E-07 16/26 K.EIGLLADEIEIYGK.S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1561.8239 -1 17271 21492 2 1561.833484 781.9192 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4 3909.5 - 593695 - - - 6.1108 - 2.808 0.548 - 790.3 1 2 0 0.0095 14 0 0 0 0.00E+00 0.00E+00 - - - 5.6765 1 230117_WJC_METTL3_WT_vs_EV_F02.21493.21493.2 4.59E-12 15/26 K.FGGDFLVYPGDPLR.F "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN" 4 1551.7722 34.57 17272 21493 2 1551.770166 776.8934 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.21 3909.6 - 581698 - - - -1.2972 - 2.891 0.642 - 655.2 1 2 0 -0.002 14 0 0 0 7.97E+06 2.31E+05 - - - 6.4462 0.9825 230117_WJC_METTL3_WT_vs_EV_F02.21497.21497.2 0.138 24-Sep K.LDNLLLDTEGFVK[136.11].L sp|Q16513|PKN2_HUMAN 1 1483.8014 -1 17276 21497 2 1483.800115 742.908 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.03 3910.1 - 370495 - - - -0.8397 - 1.319 0.129 - 85.4 1 2 0 -0.0012 13 0 0 0 0.00E+00 0.00E+00 - - - 0.704 1 230117_WJC_METTL3_WT_vs_EV_F02.21505.21505.2 5.02E-06 13/24 K.VSASPLLYTLIEK[136.11].T "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1440.8319 1.92 17283 21505 2 1440.832939 721.4232 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 5.97 3911.3 - 475412 - - - 0.6982 - 2.366 0.526 - 401.8 1 2 0 0.001 13 0 0 0 1.11E+07 5.77E+06 - - - 5.136 1 230117_WJC_METTL3_WT_vs_EV_F02.21510.21510.2 0.000497 13/16 R.IDLAVLLGK.T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 940.5957 1.92 17288 21510 2 940.595723 471.3051 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3911.9 - 1.18E+06 - - - 0.0053 - 2.51 0.487 - 448.7 1 2 0 0 9 0 0 0 2.82E+08 1.47E+08 - - - 5.3004 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21516.21516.2 3.55E-05 14-Sep R.FDMIFIVK.D "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1011.5463 0.98 17294 21516 2 1011.548523 506.7804 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 5.84 3912.7 - 482593 - - - 2.1729 - 1.811 0.437 - 210.8 1 2 0 0.0022 8 0 0 0 2.17E+06 2.21E+06 - - - 4.0591 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.21517.21517.2 0.0016 18-Aug K.VVLPTFILER[166.11].R sp|Q96SU4|OSBL9_HUMAN 1 1195.7204 2.03 17295 21517 2 1195.720188 598.8675 Oxysterol-binding protein-related protein 9 OS=Homo sapiens OX=9606 GN=OSBPL9 PE=1 SV=2 5.97 3912.8 - 442202 - - - -0.1898 - 1.653 0.394 - 161 1 2 0 -0.0002 10 0 0 0 5.31E+06 2.61E+06 - - - 3.3539 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21518.21518.2 1.68E-05 24-Oct R.FDNVLPVSLAFDK.C "sp|O95352|ATG7_HUMAN,tr|H7BZ92|H7BZ92_HUMAN,tr|H7C2R3|H7C2R3_HUMAN,tr|H7C2J8|H7C2J8_HUMAN" 4 1463.766 -1 17296 21518 2 1463.768594 732.8903 Ubiquitin-like modifier-activating enzyme ATG7 OS=Homo sapiens OX=9606 GN=ATG7 PE=1 SV=1 4.21 3913 - 429376 - - - 1.751 - 1.883 0.48 - 316 1 2 0 0.0026 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2097 0.9942 230117_WJC_METTL3_WT_vs_EV_F02.21519.21519.2 0.00228 20-Aug K.NFGLIASYLER[166.11].K "sp|O75376|NCOR1_HUMAN,tr|E7EVU5|E7EVU5_HUMAN,tr|J3KS51|J3KS51_HUMAN,tr|E7EW50|E7EW50_HUMAN,tr|A0A088AWL3|A0A088AWL3_HUMAN" 5 1291.68 1.04 17297 21519 2 1291.676921 646.8473 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 6 3913.1 - 412061 - - - -2.3891 - 1.851 0.245 - 234.8 1 2 0 -0.0031 11 0 0 0 2.08E+06 2.01E+06 - - - 2.5153 1 230117_WJC_METTL3_WT_vs_EV_F02.21527.21527.2 0.000833 16-Dec R.IDLAVLLGK[136.11].T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 948.6099 1.92 17304 21527 2 948.61033 475.3122 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3913.9 - 1.94E+06 - - - 0.4343 - 2.44 0.49 - 367.4 1 2 0 0.0004 9 0 0 0 2.82E+08 1.47E+08 - - - 5.2406 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21529.21529.2 0.000206 16-Jul R.FWYFVSQLK[136.11].K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1224.6423 0.74 17306 21529 2 1224.643682 613.3284 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3914 - 918622 - - - 1.144 - 1.533 0.492 - 159.5 1 2 0 0.0014 9 0 0 0 4.84E+07 6.50E+07 - - - 3.9105 1 230117_WJC_METTL3_WT_vs_EV_F02.21533.21533.2 0.000196 14/24 R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 1.53 17308 21533 2 1448.792208 725.4024 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3914.5 - 1.42E+06 - - - 1.3266 - 3.018 0.533 - 709 1 2 0 0.0019 13 0 0 0 1.59E+08 1.04E+08 - - - 5.8121 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21534.21534.2 0.00022 16-Jul R.FWYFVSQLK.K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1216.6281 0.74 17309 21534 2 1216.629007 609.3213 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3914.6 - 1.68E+06 - - - 0.7611 - 1.635 0.474 - 174.5 1 2 0 0.0009 9 0 0 0 4.84E+07 6.50E+07 - - - 3.964 1 230117_WJC_METTL3_WT_vs_EV_F02.21539.21539.2 0.000834 15/26 K.VLLLSSPGLEELYR[166.11].C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1597.8955 1.21 17314 21539 2 1597.896578 799.955 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3915.2 - 437886 - - - 0.6878 - 2.829 0.448 - 671.9 1 2 0 0.0011 14 0 0 0 2.11E+07 1.75E+07 - - - 4.9592 0.8895 230117_WJC_METTL3_WT_vs_EV_F02.21543.21543.2 1.84 18-Jun R.LLSLQGEQAR.R sp|Q9Y2I6|NINL_HUMAN 1 1113.6142 999 17318 21543 2 1113.611965 557.8144 Ninein-like protein OS=Homo sapiens OX=9606 GN=NINL PE=1 SV=2 6 3915.7 - 206118 - - - -2.0267 - 1.049 0.099 - 80 1 2 0 -0.0023 10 0 0 0 3.98E+06 0.00E+00 - - - -0.095 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.21547.21547.2 0.0375 14-Jun K.ENLLDFIK[136.11].H "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 998.5528 2.25 17320 21547 2 998.553868 500.2837 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.37 3916.2 - 6.33E+06 - - - 1.0726 - 1.542 0.161 - 151.5 1 2 0 0.0011 8 0 0 0 6.45E+07 2.87E+07 - - - 1.536 1 230117_WJC_METTL3_WT_vs_EV_F02.21551.21551.2 0.00344 20-Nov K.LPDVYGVFQFK.V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1311.6863 1.34 17324 21551 2 1311.687433 656.8504 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.83 3916.4 - 3.67E+06 - - - 0.8455 - 2.29 0.482 - 360.4 1 2 0 0.0011 11 0 0 0 1.56E+07 1.16E+07 - - - 4.8421 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21552.21552.3 0.000462 Nov-48 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.53 17325 21552 3 1438.783336 480.6013 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3916.5 - 2.97E+06 - - - 0.9174 - 2.544 0.385 - 203.7 1 2 0 0.0013 13 0 0 0 9.84E+06 6.42E+06 - - - 5.3636 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21555.21555.2 0.000167 20-Oct K.LPDVYGVFQFK[136.11].V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1319.7005 1.33 17328 21555 2 1319.700728 660.8575 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.83 3916.7 - 2.68E+06 - - - 0.1546 - 2.038 0.489 - 373.7 1 2 0 0.0002 11 0 0 0 1.52E+07 1.14E+07 - - - 4.5787 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21557.21557.2 0.00717 14-Oct K.LYDFYLFK.C sp|Q2TAL8|QRIC1_HUMAN 1 1107.5641 3.52 17330 21557 2 1107.565524 554.7893 Transcriptional regulator QRICH1 OS=Homo sapiens OX=9606 GN=QRICH1 PE=1 SV=1 5.83 3916.9 - 1.36E+06 - - - 1.3002 - 1.799 0.456 - 287.6 1 2 0 0.0014 8 0 0 0 4.85E+06 1.38E+06 - - - 4.1796 0.9237 230117_WJC_METTL3_WT_vs_EV_F02.21561.21561.2 4.42E-06 24-Dec K.VALVTASTDGIGF.A "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN" 5 1249.6554 - 17333 21561 2 1249.654878 625.835 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 3.8 3917.4 - 4.44E+06 - - - -0.4321 - 2.127 0.287 - 338.3 1 1 0 -0.0005 13 0 0 0 - - - - - 3.0976 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.21564.21564.2 0.0993 16-Sep K.YLDFVFAVK.N "sp|P13473|LAMP2_HUMAN,tr|H0YCG2|H0YCG2_HUMAN" 2 1100.5906 8.58 17335 21564 2 1100.593999 551.3026 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.83 3917.7 - 416533 - - - 3.0584 - 1.49 0.373 - 187.8 1 2 0 0.0034 9 0 0 0 9.62E+06 1.12E+06 - - - 2.9486 0.9983 230117_WJC_METTL3_WT_vs_EV_F02.21568.21568.2 1.25E-05 22-Oct R.LLFPAVDDNLLK[136.11].F "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1364.7795 1.8 17339 21568 2 1364.776578 683.397 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 4.21 3918.2 - 0 - - - -2.1432 - 2.04 0.437 - 302.9 1 2 0 -0.0029 12 0 0 0 1.19E+07 6.62E+06 - - - 4.1437 0.9907 230117_WJC_METTL3_WT_vs_EV_F02.21569.21569.2 0.0636 14-Jul R.SVFLTFLR.M "sp|Q9H1I8|ASCC2_HUMAN,tr|B1AH59|B1AH59_HUMAN" 2 981.5648 2.82 17340 21569 2 981.562336 491.7897 Activating signal cointegrator 1 complex subunit 2 OS=Homo sapiens OX=9606 GN=ASCC2 PE=1 SV=3 9.47 3918.3 - 0 - - - -2.4624 - 1.52 0.24 - 165.1 1 2 0 -0.0024 8 0 0 0 3.32E+06 1.17E+06 - - - 2.0757 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.21571.21571.2 0.0298 20-Oct R.EPELGLEELLR.H sp|Q9NZL4|HPBP1_HUMAN 1 1296.6925 9.94 17342 21571 2 1296.690085 649.3535 Hsp70-binding protein 1 OS=Homo sapiens OX=9606 GN=HSPBP1 PE=1 SV=2 4.09 3918.5 - 0 - - - -1.8871 - 2.059 0.425 - 296 1 2 0 -0.0024 11 0 0 0 7.72E+06 7.78E+05 - - - 4.1331 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21575.21575.2 7.25E-06 22-Dec R.LLFPAVDDNLLK.F "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1356.7653 1.8 17344 21575 2 1356.765471 679.3899 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 4.21 3919.1 - 440347 - - - 0.1238 - 2.212 0.461 - 475 1 2 0 0.0002 12 0 0 0 1.19E+07 6.62E+06 - - - 4.5348 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21576.21576.2 0.000143 22-Sep R.LNMGEIETLDDY.- "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1411.6177 - 17345 21576 2 1411.618627 706.8161 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 3.43 3919.2 - 245121 - - - 0.6482 - 1.849 0.473 - 208.9 1 2 0 0.0009 12 0 0 0 - - - - - 4.1515 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21579.21579.2 0.00169 14-Sep R.ILEFFGLK.K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 965.5586 1.89 17348 21579 2 965.560669 483.7866 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3919.5 - 684728 - - - 2.1376 - 1.618 0.401 - 201.9 1 2 0 0.0021 8 0 0 0 5.21E+07 2.76E+07 - - - 3.4534 0.984 230117_WJC_METTL3_WT_vs_EV_F02.21583.21583.2 0.0113 26-Dec K.VLLLSSPGLEELYR.C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1587.8872 1.21 17351 21583 2 1587.89617 794.9509 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3920 - 207125 - - - 5.6433 - 1.539 0.252 - 284.8 1 2 0 0.009 14 0 0 0 2.11E+07 1.75E+07 - - - 1.9814 0.9179 230117_WJC_METTL3_WT_vs_EV_F02.21585.21585.2 13.3 14-May R.ILEFFGLK[136.11].K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 973.5728 1.88 17352 21585 2 973.571238 487.7937 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3920.2 - 368037 - - - -1.6095 - 1.205 0.075 - 49.3 3 2 0 -0.0016 8 0 0 0 5.16E+07 2.75E+07 - - - -0.0563 0.9948 230117_WJC_METTL3_WT_vs_EV_F02.21590.21590.2 0.145 16-Oct K.AIVLAAIFR[166.11].C "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 982.6203 0.92 17357 21590 2 982.622385 492.3174 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 9.79 3920.5 - 0 - - - 2.1148 - 1.933 0.015 - 446.4 1 2 0 0.0021 9 0 0 0 1.84E+06 2.01E+06 - - - 1.0579 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21593.21593.2 0.637 24-Nov R.LGPLLLDPSLAVR[166.11].E sp|Q7Z4Q2|HEAT3_HUMAN 1 1372.8318 1.49 17360 21593 2 1372.834477 687.4232 HEAT repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=HEATR3 PE=1 SV=2 5.84 3920.8 - 0 - - - 1.9813 - 2.202 0.3 - 336.7 1 2 0 0.0027 13 0 0 0 5.81E+06 3.89E+06 - - - 3.2819 1 230117_WJC_METTL3_WT_vs_EV_F02.21595.21595.2 1.41E-06 26-Dec R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.14 17362 21595 2 1478.898309 740.4549 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3921 - 0 - - - 2.1016 - 2.314 0.547 - 338.7 1 2 0 0.0031 14 0 0 0 1.05E+08 9.21E+07 - - - 5.1855 0.9767 230117_WJC_METTL3_WT_vs_EV_F02.21598.21598.2 0.749 22-Jul R.FSPIPFPPLSYK.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1391.7489 2.46 17365 21598 2 1391.753464 696.8817 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3921.3 - 0 - - - 3.2614 - 1.286 0.096 - 102.8 1 2 0 0.0045 12 0 0 0 1.38E+07 5.60E+06 - - - 0.4105 1 230117_WJC_METTL3_WT_vs_EV_F02.21600.21600.2 0.000342 16/28 R.ELALALQEALEPAVR.L sp|Q5RKV6|EXOS6_HUMAN 1 1621.9039 0.97 17367 21600 2 1621.908373 811.9592 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 4.25 3921.6 - 0 - - - 2.7443 - 3.377 0.453 - 951.4 1 2 0 0.0045 15 0 0 0 4.30E+06 4.43E+06 - - - 5.3775 0.9061 230117_WJC_METTL3_WT_vs_EV_F02.21606.21606.2 1.88 16-May R.DDLLGFALR.E sp|Q9Y617|SERC_HUMAN 1 1018.5447 1.5 17372 21606 2 1018.545867 510.2796 Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1 PE=1 SV=2 4.21 3922.5 - 687775 - - - 1.1016 - 0.985 0.018 - 55.7 2 2 0 0.0011 9 0 0 0 5.65E+06 3.78E+06 - - - -1.0046 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21608.21608.2 0.000405 20-Sep K.AFVDFLSDEIK.E sp|Q07021|C1QBP_HUMAN 1 1282.6445 2.53 17374 21608 2 1282.647523 642.3295 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.03 3922.6 - 5.44E+06 - - - 2.342 - 1.741 0.454 - 222.4 1 2 0 0.003 11 0 0 0 1.61E+07 6.39E+06 - - - 3.8932 1 230117_WJC_METTL3_WT_vs_EV_F02.21609.21609.2 8.99E-06 14/22 K.WLAPDGLIFPDR[166.11].A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1408.7379 0.8 17375 21609 2 1408.741621 705.3762 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3922.6 - 5.22E+06 - - - 2.6726 - 2.805 0.505 - 700.2 1 2 0 0.0038 12 0 0 0 4.87E+07 6.06E+07 - - - 5.4835 1 230117_WJC_METTL3_WT_vs_EV_F02.21610.21610.2 1.74E-08 14/26 R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.14 17376 21610 2 1470.883866 736.4478 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3922.8 - 3.84E+06 - - - 1.9478 - 2.641 0.625 - 402.7 1 2 0 0.0029 14 0 0 0 1.05E+08 9.21E+07 - - - 6.0934 1 230117_WJC_METTL3_WT_vs_EV_F02.21611.21611.2 0.000264 22-Dec K.WLAPDGLIFPDR.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1398.7296 0.8 17377 21611 2 1398.736086 700.3721 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3922.9 - 3.45E+06 - - - 4.6471 - 2.378 0.457 - 553.3 1 2 0 0.0065 12 0 0 0 4.87E+07 6.06E+07 - - - 4.6936 1 230117_WJC_METTL3_WT_vs_EV_F02.21612.21612.2 8.80E-05 18-Nov R.IQFFAIEIAR.N sp|Q9BVG4|PBDC1_HUMAN 1 1206.6761 4.03 17378 21612 2 1206.680173 604.3453 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 6 3923 - 2.58E+06 - - - 3.3804 - 2.355 0.485 - 422.1 1 2 0 0.0041 10 0 0 0 4.90E+06 1.22E+06 - - - 5.0128 1 230117_WJC_METTL3_WT_vs_EV_F02.21613.21613.2 0.00382 18-Nov R.SLGPVELLLR.G "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1095.6652 3.01 17379 21613 2 1095.667911 548.8399 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.72 3923.1 - 2.46E+06 - - - 2.4789 - 2.122 0.49 - 447.2 1 2 0 0.0027 10 0 0 0 6.69E+06 2.22E+06 - - - 4.7594 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.21614.21614.2 0.0137 16-Aug K.EVNLVLLLK.N "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1039.6641 999 17380 21614 2 1039.668683 520.8393 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 6.1 3923.2 - 1.58E+06 - - - 4.3774 - 1.719 0.314 - 233.2 1 2 0 0.0046 9 0 0 0 5.23E+06 0.00E+00 - - - 2.9261 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.21616.21616.2 0.00694 18-Jul R.LLVPILLPEK.C "sp|O75352|MPU1_HUMAN,tr|J3KSI4|J3KSI4_HUMAN,tr|J3KTK8|J3KTK8_HUMAN,tr|I3L1D2|I3L1D2_HUMAN,tr|I3L295|I3L295_HUMAN,tr|J3KT75|J3KT75_HUMAN,tr|J3QRD5|J3QRD5_HUMAN,tr|J3QS48|J3QS48_HUMAN,tr|J3QW43|J3QW43_HUMAN,tr|I3L261|I3L261_HUMAN,tr|I3L4E0|I3L4E0_HUMAN,tr|J3QQZ4|J3QQZ4_HUMAN,tr|I3L405|I3L405_HUMAN,tr|I3L4T1|I3L4T1_HUMAN" 14 1133.7424 -1 17382 21616 2 1133.744988 567.8785 Mannose-P-dolichol utilization defect 1 protein OS=Homo sapiens OX=9606 GN=MPDU1 PE=1 SV=2 6 3923.5 - 1.21E+06 - - - 2.2977 - 1.66 0.209 - 148.9 1 2 0 0.0026 10 0 0 0 0.00E+00 0.00E+00 - - - 1.9985 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21619.21619.2 0.0012 18-Sep R.SLGPVELLLR[166.11].G "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1105.6735 3.16 17385 21619 2 1105.676454 553.844 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.72 3923.9 - 953111 - - - 2.7033 - 1.887 0.446 - 250.9 1 2 0 0.003 10 0 0 0 8.58E+06 2.72E+06 - - - 4.1067 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.21620.21620.2 0.00417 18-Aug R.LLVPILLPEK[136.11].C "sp|O75352|MPU1_HUMAN,tr|J3KSI4|J3KSI4_HUMAN,tr|J3KTK8|J3KTK8_HUMAN,tr|I3L1D2|I3L1D2_HUMAN,tr|I3L295|I3L295_HUMAN,tr|J3KT75|J3KT75_HUMAN,tr|J3QRD5|J3QRD5_HUMAN,tr|J3QS48|J3QS48_HUMAN,tr|J3QW43|J3QW43_HUMAN,tr|I3L261|I3L261_HUMAN,tr|I3L4E0|I3L4E0_HUMAN,tr|J3QQZ4|J3QQZ4_HUMAN,tr|I3L405|I3L405_HUMAN,tr|I3L4T1|I3L4T1_HUMAN" 14 1141.7566 -1 17386 21620 2 1141.759704 571.8856 Mannose-P-dolichol utilization defect 1 protein OS=Homo sapiens OX=9606 GN=MPDU1 PE=1 SV=2 6 3924 - 870523 - - - 2.7335 - 1.565 0.427 - 178.8 1 2 0 0.0031 10 0 0 0 0.00E+00 0.00E+00 - - - 3.444 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21622.21622.2 9.66E-05 26-Nov K.IPVDTYNNILTVLK[136.11].L sp|Q96QK1|VPS35_HUMAN 1 1609.9171 -1 17388 21622 2 1609.917341 805.9658 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 5.83 3924.3 - 536867 - - - 0.1752 - 2.155 0.452 - 193.4 1 2 0 0.0003 14 0 0 0 0.00E+00 0.00E+00 - - - 4.3061 1 230117_WJC_METTL3_WT_vs_EV_F02.21626.21626.2 1.58E-05 13/24 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.53 17391 21626 2 1438.786107 720.3983 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3924.8 - 2.14E+06 - - - 2.8434 - 2.975 0.406 - 645.5 1 2 0 0.0041 13 0 0 0 1.59E+08 1.04E+08 - - - 4.8366 1 230117_WJC_METTL3_WT_vs_EV_F02.21628.21628.2 8.13E-08 22-Nov R.YFPTQALNFAFK[136.11].D "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 1453.7485 1.09 17393 21628 2 1453.755566 727.8815 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.59 3925 - 1.71E+07 - - - 4.8351 - 2.162 0.635 - 410.5 1 2 0 0.007 12 0 0 0 8.93E+07 8.21E+07 - - - 5.7576 1 230117_WJC_METTL3_WT_vs_EV_F02.21633.21633.2 8.56E-06 16/28 R.ELALALQEALEPAVR[166.11].L sp|Q5RKV6|EXOS6_HUMAN 1 1631.9122 0.97 17398 21633 2 1631.91869 816.9634 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 4.25 3925.6 - 1.11E+06 - - - 3.9818 - 2.964 0.486 - 947.7 1 2 0 0.0065 15 0 0 0 4.30E+06 4.43E+06 - - - 5.2999 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21634.21634.3 2.88E-05 15/52 R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.24 17399 21634 3 1478.901609 493.9723 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3925.7 - 1.01E+06 - - - 4.333 - 2.457 0.547 - 263 1 2 0 0.0064 14 0 0 0 1.56E+07 1.25E+07 - - - 7.0257 1 230117_WJC_METTL3_WT_vs_EV_F02.21635.21635.3 2.64E-08 17/52 R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.24 17400 21635 3 1470.887406 491.3009 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3925.8 - 1.00E+06 - - - 4.3545 - 2.692 0.6 - 351.5 1 2 0 0.0064 14 0 0 0 1.56E+07 1.25E+07 - - - 7.8593 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.21636.21636.3 4.11E-05 18/80 R.IPLNPYLNLHSLLPASNLAGK.E "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2244.263 -1 17401 21636 3 2244.268923 749.095 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.6 3926 - 984311 - - - 2.6218 - 2.896 0.372 - 228.5 1 2 0 0.0059 21 0 0 0 0.00E+00 0.00E+00 - - - 5.2351 1 230117_WJC_METTL3_WT_vs_EV_F02.21637.21637.2 2.30E-05 26-Sep K.LFGIESSSGTILWK.Q sp|Q8N766|EMC1_HUMAN 1 1536.8188 -1 17402 21637 2 1536.828328 769.4167 ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1 6 3926.1 - 604942 - - - 6.2031 - 2.095 0.526 - 183.8 1 2 0 0.0095 14 0 0 0 0.00E+00 0.00E+00 - - - 4.7789 1 230117_WJC_METTL3_WT_vs_EV_F02.21638.21638.2 1.44E-06 18/26 K.TALALAIAQELGSK.V "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1384.7926 -1 17403 21638 2 1384.80258 693.4036 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 5.66 3926.2 - 569315 - - - 7.2213 - 3.569 0.574 - 1509 1 2 0 0.01 14 0 0 0 0.00E+00 0.00E+00 - - - 6.4702 0.976 230117_WJC_METTL3_WT_vs_EV_F02.21642.21642.2 0.025 20-Sep K.LDTSQWPLLLK[136.11].N "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1320.7533 0.91 17407 21642 2 1320.765571 661.3839 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 5.84 3926.7 - 388389 - - - 9.3 - 2.149 0.317 - 359 1 2 0 0.0123 11 0 0 0 8.54E+06 9.39E+06 - - - 3.448 0.9955 230117_WJC_METTL3_WT_vs_EV_F02.21645.21645.3 0.0328 Sep-76 R.LFPPWIK[136.11]PADTEPPPLLVYK[136.11].W "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 2336.3155 -1 17410 21645 3 2336.326073 779.7791 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.07 3927.1 - 362282 - - - 4.5135 - 1.913 0.278 - 77.1 1 2 0 0.0105 20 0 0 0 0.00E+00 0.00E+00 - - - 3.2102 1 230117_WJC_METTL3_WT_vs_EV_F02.21650.21650.2 1.16E-10 13/30 K.LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1793.9075 0.88 17414 21650 2 1793.909946 897.961 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3927.7 - 1.30E+06 - - - 1.3635 - 2.851 0.652 - 367.8 1 2 0 0.0024 16 0 0 0 2.44E+07 2.76E+07 - - - 6.4316 1 230117_WJC_METTL3_WT_vs_EV_F02.21652.21652.2 2.65E-07 17/30 K.LFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1783.8992 0.88 17416 21652 2 1783.899814 892.9569 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3927.8 - 1.11E+06 - - - 0.3274 - 3.284 0.634 - 786.6 1 2 0 0.0006 16 0 0 0 2.44E+07 2.76E+07 - - - 6.6469 0.9868 230117_WJC_METTL3_WT_vs_EV_F02.21653.21653.2 0.43 16-Jun R.FYELLVTGR.Y "sp|Q9UPS6|SET1B_HUMAN,tr|A0A0A0MQV9|A0A0A0MQV9_HUMAN" 2 1096.5917 2.25 17417 21653 2 1096.591346 549.3031 Histone-lysine N-methyltransferase SETD1B OS=Homo sapiens OX=9606 GN=SETD1B PE=1 SV=3 6 3927.9 - 978546 - - - -0.3192 - 1.192 0.171 - 114 2 2 0 -0.0003 9 0 0 0 4.96E+06 2.20E+06 - - - 0.6775 0.9502 230117_WJC_METTL3_WT_vs_EV_F02.21654.21654.2 0.0119 20-Jul Q.AFADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1170.7012 15.9 17418 21654 2 1170.702915 586.3579 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3927.9 - 729255 - - - 1.4256 - 1.625 0.339 - 122.2 1 1 0 0.0017 11 0 0 0 3.84E+06 2.41E+05 - - - 2.8577 0.9956 230117_WJC_METTL3_WT_vs_EV_F02.21655.21655.2 0.00318 14-Jul R.SWLLPVIR[166.11].D sp|Q5JTH9|RRP12_HUMAN 1 992.6047 1.22 17419 21655 2 992.606483 497.3096 RRP12-like protein OS=Homo sapiens OX=9606 GN=RRP12 PE=1 SV=2 9.47 3928 - 528407 - - - 1.8396 - 1.479 0.122 - 279.1 1 2 0 0.0018 8 0 0 0 2.55E+06 2.08E+06 - - - 1.1219 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21665.21665.2 7.12E-05 20-Dec K.LDTSQWPLLLK.N "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1312.7391 0.92 17429 21665 2 1312.740609 657.3768 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 5.84 3929 - 213574 - - - 1.1586 - 2.373 0.393 - 622.8 1 2 0 0.0015 11 0 0 0 8.63E+06 9.39E+06 - - - 4.281 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21672.21672.2 0.0574 18-Oct R.DAVLLLFANK.Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1102.6386 2.33 17435 21672 2 1102.640942 552.3266 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3929.7 - 3.38E+06 - - - 2.0823 - 2.266 0.354 - 465.6 1 2 0 0.0023 10 0 0 0 2.64E+07 1.13E+07 - - - 3.9383 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21673.21673.2 0.000412 18-Nov R.VVTDLISLIR.Q sp|P38432|COIL_HUMAN 1 1127.6914 1.19 17436 21673 2 1127.692842 564.853 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3929.7 - 3.09E+06 - - - 1.2699 - 2.098 0.333 - 496 1 2 0 0.0014 10 0 0 0 6.55E+06 5.53E+06 - - - 3.5684 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.21675.21675.2 0.00525 18-Jul R.VVTDLISLIR[166.11].Q sp|P38432|COIL_HUMAN 1 1137.6997 1.19 17438 21675 2 1137.700259 569.8571 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3929.8 - 2.69E+06 - - - 0.5089 - 1.58 0.386 - 183.3 1 2 0 0.0006 10 0 0 0 6.55E+06 5.53E+06 - - - 3.1686 1 230117_WJC_METTL3_WT_vs_EV_F02.21678.21678.3 1.65E-06 Nov-60 K.LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1793.9075 -1 17441 21678 3 1793.911129 598.9764 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3930 - 1.93E+06 - - - 2.023 - 2.307 0.529 - 166.4 1 2 0 0.0036 16 0 0 0 0.00E+00 0.00E+00 - - - 6.5817 1 230117_WJC_METTL3_WT_vs_EV_F02.21679.21679.2 3.92E-07 26-Nov K.TYVLNPLAPEFIPR.A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1628.8926 -1 17442 21679 2 1628.897197 815.4536 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.66 3930.1 - 1.78E+06 - - - 2.8044 - 2.253 0.607 - 313.1 1 2 0 0.0046 14 0 0 0 0.00E+00 0.00E+00 - - - 5.5612 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21681.21681.3 0.0238 Sep-60 K.LFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1783.8992 -1 17444 21681 3 1783.900644 595.6404 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3930.2 - 1.31E+06 - - - 0.7926 - 2.178 0.416 - 105.4 1 2 0 0.0014 16 0 0 0 0.00E+00 0.00E+00 - - - 5.1749 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21682.21682.2 0.0057 18-Sep R.DAVLLLFANK[136.11].Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1110.6528 2.32 17445 21682 2 1110.653983 556.3337 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3930.3 - 1.26E+06 - - - 1.0237 - 2.046 0.358 - 326.5 1 2 0 0.0011 10 0 0 0 2.63E+07 1.13E+07 - - - 3.6831 1 230117_WJC_METTL3_WT_vs_EV_F02.21687.21687.2 3.55E-07 20-Oct R.FLEEFITPIVK[136.11].V "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 1342.7628 1.12 17450 21687 2 1342.764944 672.3887 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.53 3930.8 - 687126 - - - 1.6042 - 2.08 0.598 - 235.6 1 2 0 0.0022 11 0 0 0 6.37E+06 5.68E+06 - - - 5.4384 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21689.21689.2 0.000364 26-Sep K.TYVLNPLAPEFIPR[166.11].A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1638.9009 -1 17451 21689 2 1638.902405 820.4577 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.66 3931.2 - 115835 - - - 0.9189 - 1.734 0.385 - 239.6 1 2 0 0.0015 14 0 0 0 0.00E+00 0.00E+00 - - - 3.2654 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21693.21693.2 0.000283 20-Sep R.LFEFAGYDVLR[166.11].L sp|P54136|SYRC_HUMAN 1 1338.6848 -1 17455 21693 2 1338.686737 670.3497 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3931.4 - 2.43E+06 - - - 1.4783 - 2.089 0.458 - 234.9 1 2 0 0.002 11 0 0 0 0.00E+00 0.00E+00 - - - 4.4161 0.9554 230117_WJC_METTL3_WT_vs_EV_F02.21696.21696.2 0.153 16-Aug N.VLIIGELLK.Q "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 996.6583 12.13 17458 21696 2 996.659887 499.3364 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.97 3931.6 - 1.09E+06 - - - 1.5733 - 1.686 0.334 - 188.5 1 1 0 0.0016 9 0 0 0 5.03E+06 4.14E+05 - - - 3.0186 1 230117_WJC_METTL3_WT_vs_EV_F02.21698.21698.2 4.01E-11 18/30 R.IIGATDSSGELMFLMK.W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1711.8525 1.42 17460 21698 2 1711.854537 856.9335 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3931.8 - 837379 - - - 1.2016 - 3.632 0.677 - 751.9 1 2 0 0.0021 16 0 0 0 2.01E+07 1.42E+07 - - - 7.2117 1 230117_WJC_METTL3_WT_vs_EV_F02.21703.21703.2 4.89E-07 19/30 R.IIGATDSSGELMFLMK[136.11].W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1719.8667 1.42 17465 21703 2 1719.866681 860.9406 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3932.3 - 645497 - - - 0.0006 - 3.638 0.597 - 739.1 1 2 0 0 16 0 0 0 2.01E+07 1.42E+07 - - - 6.6255 0.9862 230117_WJC_METTL3_WT_vs_EV_F02.21704.21704.3 0.0159 Nov-40 K.IR[166.11]FLILPDMLK[136.11].N sp|P62318|SMD3_HUMAN 1 1375.838 -1 17466 21704 3 1375.83856 459.62 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 8.75 3932.4 - 515693 - - - 0.3823 - 2.057 0.384 - 240.2 1 2 1 0.0005 11 0 0 0 0.00E+00 0.00E+00 - - - 4.87 1 230117_WJC_METTL3_WT_vs_EV_F02.21712.21712.2 0.000421 20-Dec R.LFEFAGYDVLR.L sp|P54136|SYRC_HUMAN 1 1328.6765 -1 17472 21712 2 1328.68336 665.3455 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3933.3 - 3.99E+06 - - - 5.1721 - 2.308 0.514 - 605.5 1 2 0 0.0069 11 0 0 0 0.00E+00 0.00E+00 - - - 5.0979 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21713.21713.2 0.00368 18-Oct R.DALLLIFANK.Q "sp|P36406|TRI23_HUMAN,sp|P62330|ARF6_HUMAN" 2 1116.6543 1.51 17473 21713 2 1116.657319 559.3344 E3 ubiquitin-protein ligase TRIM23 OS=Homo sapiens OX=9606 GN=TRIM23 PE=1 SV=1 5.84 3933.4 - 2.85E+06 - - - 2.7072 - 2.115 0.427 - 333.9 1 2 0 0.003 10 0 0 0 1.57E+07 1.04E+07 - - - 4.2847 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21716.21716.2 0.000151 20-Nov K.VTDLLGGLFSK[136.11].T "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1156.6583 2.31 17476 21716 2 1156.65973 579.3364 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.81 3933.5 - 2.69E+06 - - - 1.2147 - 2.508 0.352 - 572.7 1 2 0 0.0014 11 0 0 0 5.44E+07 2.36E+07 - - - 4.1279 1 230117_WJC_METTL3_WT_vs_EV_F02.21718.21718.2 8.69E-09 14/24 K.SVDPTLALSVYLR[166.11].A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1442.8009 0.9 17478 21718 2 1442.804498 722.4077 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.55 3933.6 - 1.73E+06 - - - 2.5284 - 2.685 0.573 - 588.3 1 2 0 0.0036 13 0 0 0 1.12E+07 1.24E+07 - - - 5.8069 1 230117_WJC_METTL3_WT_vs_EV_F02.21720.21720.2 1.48E-07 20-Nov R.VINQMLEFAFR.Y "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 1366.7067 -1 17480 21720 2 1366.708393 684.3606 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 5.97 3933.7 - 1.42E+06 - - - 1.208 - 2.544 0.59 - 444.9 1 2 0 0.0017 11 0 0 0 0.00E+00 0.00E+00 - - - 5.9242 0.999 230117_WJC_METTL3_WT_vs_EV_F02.21721.21721.2 0.0016 16-Aug K.APWELLELR[166.11].V "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A6Q8PF15|A0A6Q8PF15_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN,tr|A0A6Q8PFC1|A0A6Q8PFC1_HUMAN" 6 1135.6265 0.7 17481 21721 2 1135.625691 568.8205 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.53 3933.8 - 1.25E+06 - - - -0.7256 - 1.528 0.423 - 255.8 1 2 0 -0.0008 9 0 0 0 5.19E+06 7.43E+06 - - - 3.3916 1 230117_WJC_METTL3_WT_vs_EV_F02.21722.21722.2 4.09E-07 20-Dec R.VINQMLEFAFR[166.11].Y "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 1376.715 -1 17482 21722 2 1376.719147 689.3648 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 5.97 3933.8 - 992744 - - - 3.0035 - 2.55 0.544 - 580.4 1 2 0 0.0041 11 0 0 0 0.00E+00 0.00E+00 - - - 5.59 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.21724.21724.2 0.169 16-Aug R.LVTLEEFLK.A "sp|P80303|NUCB2_HUMAN,tr|H0YD18|H0YD18_HUMAN,tr|E9PKG6|E9PKG6_HUMAN" 3 1090.6274 -1 17484 21724 2 1090.629168 546.321 Nucleobindin-2 OS=Homo sapiens OX=9606 GN=NUCB2 PE=1 SV=3 4.53 3934 - 808805 - - - 1.6101 - 1.61 0.257 - 154.6 1 2 0 0.0018 9 0 0 0 0.00E+00 0.00E+00 - - - 2.3164 1 230117_WJC_METTL3_WT_vs_EV_F02.21725.21725.2 2.14E-05 26-Nov R.ILLDIDNDTESTAL.- sp|Q68EM7|RHG17_HUMAN 1 1531.7617 - 17485 21725 2 1531.765154 766.8881 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 3.37 3934.1 - 566360 - - - 2.2327 - 2.308 0.514 - 309.2 1 2 0 0.0034 14 0 0 0 - - - - - 4.9352 1 230117_WJC_METTL3_WT_vs_EV_F02.21728.21728.2 3.09E-12 15/30 K.IIGATDSC[160.03]GDLMFLMK.W sp|P45973|CBX5_HUMAN 1 1770.8355 -1 17488 21728 2 1770.832125 886.425 Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1 4.21 3934.4 - 470861 - - - -1.8776 - 3.207 0.679 - 512.8 1 2 0 -0.0033 16 0 0 0 0.00E+00 0.00E+00 - - - 6.9201 0.9974 230117_WJC_METTL3_WT_vs_EV_F02.21729.21729.2 0.000264 20-Dec R.FFPLESWQIGK.L "sp|P30046|DOPD_HUMAN,tr|J3KQ18|J3KQ18_HUMAN,tr|H7C342|H7C342_HUMAN" 3 1350.6972 0.9 17489 21729 2 1350.693736 676.3559 D-dopachrome decarboxylase OS=Homo sapiens OX=9606 GN=DDT PE=1 SV=3 6 3934.5 - 452415 - - - -2.5816 - 2.14 0.363 - 303.5 1 2 0 -0.0035 11 0 0 0 2.90E+06 3.22E+06 - - - 3.7792 1 230117_WJC_METTL3_WT_vs_EV_F02.21734.21734.2 1.60E-07 28-Nov R.LWLDGYSVTDAVALR.V "sp|O43427|FIBP_HUMAN,tr|E9PJW6|E9PJW6_HUMAN" 2 1677.8726 -1 17493 21734 2 1677.87813 839.9436 Acidic fibroblast growth factor intracellular-binding protein OS=Homo sapiens OX=9606 GN=FIBP PE=1 SV=3 4.21 3935 - 209821 - - - 3.2827 - 2.506 0.545 - 408.3 1 2 0 0.0055 15 0 0 0 0.00E+00 0.00E+00 - - - 5.3233 1 230117_WJC_METTL3_WT_vs_EV_F02.21735.21735.2 9.37E-11 18/30 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 0.94 17494 21735 2 1807.92449 904.9689 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3935.1 - 1.09E+07 - - - 0.7412 - 3.342 0.6 - 1055.1 1 2 0 0.0013 16 0 0 0 7.13E+07 7.55E+07 - - - 6.4386 1 230117_WJC_METTL3_WT_vs_EV_F02.21737.21737.2 1.49E-11 18/30 K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 0.94 17496 21737 2 1797.916094 899.9647 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3935.1 - 8.69E+06 - - - 0.6752 - 3.564 0.644 - 1062.5 1 2 0 0.0012 16 0 0 0 7.13E+07 7.55E+07 - - - 6.9217 1 230117_WJC_METTL3_WT_vs_EV_F02.21738.21738.3 4.18E-07 16/60 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 0.87 17497 21738 3 1807.925396 603.6483 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3935.2 - 2.90E+06 - - - 1.2423 - 2.938 0.582 - 348.8 1 2 0 0.0022 16 0 0 0 1.40E+07 1.62E+07 - - - 7.7934 1 230117_WJC_METTL3_WT_vs_EV_F02.21739.21739.2 3.51E-06 20-Nov K.YPSPFFVFGEK.L sp|Q08211|DHX9_HUMAN 1 1316.6441 0.97 17498 21739 2 1316.645506 659.3293 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3935.3 - 2.70E+06 - - - 1.0489 - 2.225 0.483 - 474 1 2 0 0.0014 11 0 0 0 1.16E+08 1.19E+08 - - - 4.7715 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.21741.21741.3 0.000154 Dec-60 K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 0.87 17500 21741 3 1797.913185 600.3122 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3935.4 - 2.30E+06 - - - -0.9428 - 2.514 0.435 - 113.9 1 2 0 -0.0017 16 0 0 0 1.40E+07 1.62E+07 - - - 5.7548 1 230117_WJC_METTL3_WT_vs_EV_F02.21744.21744.2 4.41E-09 22-Dec R.FSTFFDDAPVFR.L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1447.6772 -1 17503 21744 2 1447.677223 724.8459 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3935.6 - 1.60E+06 - - - 0.0048 - 2.299 0.604 - 453.8 1 2 0 0 12 0 0 0 0.00E+00 0.00E+00 - - - 5.6925 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.21747.21747.2 0.00162 18-Oct K.AWLLSMIQSK.C "sp|Q9UBU9|NXF1_HUMAN,tr|E9PLA7|E9PLA7_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1175.6373 0.95 17506 21747 2 1175.637624 588.8259 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 8.8 3936 - 1.25E+06 - - - 0.3045 - 1.816 0.35 - 333.6 1 2 0 0.0004 10 0 0 0 5.42E+06 5.72E+06 - - - 3.2914 1 230117_WJC_METTL3_WT_vs_EV_F02.21748.21748.2 0.000326 13/18 K.AWLLSMIQSK[136.11].C "sp|Q9UBU9|NXF1_HUMAN,tr|E9PLA7|E9PLA7_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1183.6515 -1 17507 21748 2 1183.651577 592.833 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 8.8 3936.1 - 1.25E+06 - - - 0.0938 - 2.473 0.447 - 634 1 2 0 0.0001 10 0 0 0 0.00E+00 0.00E+00 - - - 4.8698 1 230117_WJC_METTL3_WT_vs_EV_F02.21749.21749.2 8.11E-07 14/22 R.FSTFFDDAPVFR[166.11].L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1457.6855 -1 17508 21749 2 1457.68623 729.85 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3936.2 - 1.09E+06 - - - 0.5104 - 2.562 0.576 - 601.8 1 2 0 0.0007 12 0 0 0 0.00E+00 0.00E+00 - - - 5.7705 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21754.21754.3 0.000362 Nov-40 R.SVVTVIDVFYK.Y sp|Q5D862|FILA2_HUMAN 1 1268.7016 -1 17512 21754 3 1268.701684 423.9078 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 5.55 3936.8 - 852523 - - - 0.0347 - 2.051 0.314 - 188.6 1 2 0 0 11 0 0 0 0.00E+00 0.00E+00 - - - 4.0814 0.9966 230117_WJC_METTL3_WT_vs_EV_F02.21755.21755.2 0.14 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 17513 21755 2 1603.7605 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3936.9 - 843445 - - - -2.145 - 1.731 0.336 - 206.3 1 2 0 -0.0034 12 0 0 0 4.77E+06 0.00E+00 - - - 2.9653 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21756.21756.2 0.000767 20-Nov K.YPSPFFVFGEK[136.11].L sp|Q08211|DHX9_HUMAN 1 1324.6583 0.97 17514 21756 2 1324.659929 663.3364 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3936.9 - 1.20E+07 - - - 1.2109 - 2.144 0.463 - 450.3 1 2 0 0.0016 11 0 0 0 1.16E+08 1.19E+08 - - - 4.5234 1 230117_WJC_METTL3_WT_vs_EV_F02.21757.21757.2 7.90E-06 14/24 K.TPFLLVGTQIDLR.D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1471.8399 1.36 17515 21757 2 1471.841864 736.9272 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3937 - 5.53E+06 - - - 1.3582 - 2.955 0.576 - 799.1 1 2 0 0.002 13 0 0 0 1.53E+07 1.13E+07 - - - 6.0755 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21758.21758.2 4.85E-05 20-Sep R.ASILNTWISLK.Q "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN" 2 1244.7129 1.61 17516 21758 2 1244.71521 623.3637 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 8.8 3937 - 5.27E+06 - - - 1.8775 - 2.361 0.433 - 180.1 1 2 0 0.0023 11 0 0 0 1.97E+07 1.22E+07 - - - 4.5624 1 230117_WJC_METTL3_WT_vs_EV_F02.21759.21759.2 0.000244 13/24 K.TPFLLVGTQIDLR[166.11].D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1481.8481 1.36 17517 21759 2 1481.850131 741.9313 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3937.1 - 4.34E+06 - - - 1.347 - 3.042 0.569 - 655 1 2 0 0.002 13 0 0 0 1.53E+07 1.13E+07 - - - 6.0983 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21760.21760.2 0.000118 20-Sep R.ASILNTWISLK[136.11].Q "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN" 2 1252.7271 1.61 17518 21760 2 1252.730336 627.3708 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 8.8 3937.1 - 3.32E+06 - - - 2.6047 - 2.196 0.457 - 343 1 2 0 0.0033 11 0 0 0 1.97E+07 1.22E+07 - - - 4.5434 1 230117_WJC_METTL3_WT_vs_EV_F02.21761.21761.3 4.92E-06 15/48 K.TPFLLVGTQIDLR.D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1471.8399 -1 17519 21761 3 1471.841389 491.6206 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3937.2 - 2.03E+06 - - - 1.0354 - 2.743 0.474 - 295.5 1 2 0 0.0015 13 0 0 0 0.00E+00 0.00E+00 - - - 6.56 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21762.21762.2 0.000702 14-Aug R.GFGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 921.5204 1.11 17520 21762 2 921.521891 461.7675 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3937.3 - 1.82E+06 - - - 1.6451 - 1.411 0.441 - 173.5 1 2 0 0.0015 8 0 0 0 5.96E+08 5.36E+08 - - - 3.3361 1 230117_WJC_METTL3_WT_vs_EV_F02.21763.21763.2 3.41E-07 16/30 K.LFIGGLSFETTDDSLR[166.11].E "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1779.8918 -1 17521 21763 2 1779.895112 890.9532 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.03 3937.4 - 1.69E+06 - - - 1.8327 - 3.025 0.587 - 728.8 1 2 0 0.0033 16 0 0 0 0.00E+00 0.00E+00 - - - 6.0969 1 230117_WJC_METTL3_WT_vs_EV_F02.21764.21764.2 3.39E-08 13/24 K.SVDPTLALSVYLR.A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1432.7926 0.9 17522 21764 2 1432.796632 717.4036 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.55 3937.4 - 1.67E+06 - - - 2.828 - 2.267 0.561 - 598.2 1 2 0 0.0041 13 0 0 0 1.12E+07 1.24E+07 - - - 5.2839 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21765.21765.3 0.000501 Dec-48 K.TPFLLVGTQIDLR[166.11].D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1481.8481 1.54 17523 21765 3 1481.849161 494.9567 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3937.5 - 1.58E+06 - - - 0.6924 - 2.417 0.385 - 196.9 1 2 0 0.001 13 0 0 0 4.23E+06 2.75E+06 - - - 5.2249 0.9896 230117_WJC_METTL3_WT_vs_EV_F02.21767.21767.2 0.00716 16-Sep K.GVIDLIFEK.A "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 1032.5855 2.63 17525 21767 2 1032.587725 517.3001 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 3937.6 - 1.50E+06 - - - 2.1083 - 1.575 0.026 - 183.8 1 2 0 0.0022 9 0 0 0 7.31E+06 2.78E+06 - - - 0.5465 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21768.21768.2 0.000288 14-Sep R.GFGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 913.5062 1.11 17526 21768 2 913.50678 457.7604 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3937.7 - 1.31E+06 - - - 0.6623 - 1.547 0.462 - 242.6 1 2 0 0.0006 8 0 0 0 5.96E+08 5.36E+08 - - - 3.7691 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21769.21769.2 6.65E-05 20-Sep K.FIWSEISYLSK.W sp|Q16706|MA2A1_HUMAN 1 1371.7075 -1 17527 21769 2 1371.708327 686.861 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 6 3937.8 - 1.29E+06 - - - 0.6364 - 1.876 0.495 - 251.5 1 2 0 0.0009 11 0 0 0 0.00E+00 0.00E+00 - - - 4.3988 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21772.21772.2 0.00759 18-Nov K.SAFLQAFLGR.G sp|Q8IXI1|MIRO2_HUMAN 1 1108.6029 0.72 17530 21772 2 1108.604261 555.3087 Mitochondrial Rho GTPase 2 OS=Homo sapiens OX=9606 GN=RHOT2 PE=1 SV=2 9.47 3938.1 - 1.18E+06 - - - 1.2015 - 1.886 0.379 - 305.8 1 2 0 0.0013 10 0 0 0 3.32E+06 4.63E+06 - - - 3.6108 1 230117_WJC_METTL3_WT_vs_EV_F02.21773.21773.2 0.0223 13/24 N.IVGLVGVDQFLVK[136.11].T sp|P13639|EF2_HUMAN 1 1393.8424 -1 17531 21773 2 1393.845304 697.9285 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3938.1 - 1.16E+06 - - - 2.0562 - 2.49 0.477 - 450.3 1 1 0 0.0029 13 0 0 0 0.00E+00 0.00E+00 - - - 4.9046 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21775.21775.2 0.0149 20-Dec R.TPGGVFLNLLK[136.11].N sp|Q9H814|PHAX_HUMAN 1 1165.695 0.64 17532 21775 2 1165.696561 583.8548 Phosphorylated adapter RNA export protein OS=Homo sapiens OX=9606 GN=PHAX PE=1 SV=1 8.41 3938.3 - 1.38E+06 - - - 1.3005 - 1.65 0.372 - 267.5 1 2 0 0.0015 11 0 0 0 4.70E+06 7.37E+06 - - - 3.1428 1 230117_WJC_METTL3_WT_vs_EV_F02.21777.21777.2 0.000386 20-Dec R.IFGLLMGTLQK.F sp|Q9H307|PININ_HUMAN 1 1219.6999 1.26 17534 21777 2 1219.702134 610.8572 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3938.4 - 1.04E+07 - - - 1.8595 - 2.507 0.509 - 454.3 1 2 0 0.0023 11 0 0 0 6.21E+07 4.94E+07 - - - 5.2861 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21778.21778.2 0.00113 20-Sep R.IFGLLMGTLQK[136.11].F sp|Q9H307|PININ_HUMAN 1 1227.7141 1.26 17535 21778 2 1227.716242 614.8643 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3938.5 - 1.00E+07 - - - 1.7724 - 1.935 0.436 - 202.7 1 2 0 0.0022 11 0 0 0 6.21E+07 4.94E+07 - - - 4.0464 1 230117_WJC_METTL3_WT_vs_EV_F02.21783.21783.2 2.24E-05 22-Dec K.VPGLYVIDSIVR[166.11].Q "sp|O95104|SCAF4_HUMAN,sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 3 1339.7739 -1 17540 21783 2 1339.77633 670.8942 SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3 5.81 3938.8 - 1.70E+06 - - - 1.8085 - 2.373 0.472 - 593.2 1 2 0 0.0024 12 0 0 0 0.00E+00 0.00E+00 - - - 4.8002 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21785.21785.2 0.0116 18-Sep K.SLESFVELMK.T sp|Q6KB66|K2C80_HUMAN 1 1181.6002 -1 17542 21785 2 1181.602513 591.8074 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 4.53 3938.9 - 1.61E+06 - - - 1.9482 - 2.086 0.381 - 185.8 1 2 0 0.0023 10 0 0 0 0.00E+00 0.00E+00 - - - 3.9066 0.999 230117_WJC_METTL3_WT_vs_EV_F02.21786.21786.2 0.0908 16-Sep K.LLELDSFLK.E "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|K9J957|K9J957_HUMAN,tr|B7Z8D3|B7Z8D3_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 5 1076.6118 0.91 17543 21786 2 1076.613491 539.3132 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.37 3939 - 1.18E+06 - - - 1.606 - 1.683 0.249 - 145.7 1 2 0 0.0017 9 0 0 0 1.18E+07 1.30E+07 - - - 2.3856 0.9841 230117_WJC_METTL3_WT_vs_EV_F02.21787.21787.2 0.761 14-Jul R.FWPIIQIR.L "sp|Q14999|CUL7_HUMAN,sp|Q8IWT3|CUL9_HUMAN,tr|A0A669KB95|A0A669KB95_HUMAN,tr|A0A669KAU7|A0A669KAU7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN,tr|E9PEZ1|E9PEZ1_HUMAN" 6 1071.6229 1.49 17544 21787 2 1071.626809 536.8187 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 9.75 3939.2 - 823303 - - - 3.6141 - 1.334 0.127 - 171.7 1 2 0 0.0039 8 0 0 0 2.12E+06 1.42E+06 - - - 0.8469 0.997 230117_WJC_METTL3_WT_vs_EV_F02.21788.21788.2 0.576 18-Aug K.IATLISSFLK[136.11].E "sp|O95394|AGM1_HUMAN,tr|A0A494C1E2|A0A494C1E2_HUMAN,tr|J3KN95|J3KN95_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C1Q4|A0A494C1Q4_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|A0A087WT27|A0A087WT27_HUMAN" 7 1099.6732 -1 17545 21788 2 1099.67544 550.8439 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 8.75 3939.3 - 765618 - - - 1.9942 - 1.454 0.187 - 136.4 1 2 0 0.0022 10 0 0 0 0.00E+00 0.00E+00 - - - 1.4663 0.9962 230117_WJC_METTL3_WT_vs_EV_F02.21790.21790.2 0.804 26-Aug K.IDQISIEELDIIYK.V sp|Q9Y295|DRG1_HUMAN 1 1690.9029 -1 17547 21790 2 1690.902611 846.4587 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 3.92 3939.5 - 641278 - - - -0.1822 - 1.378 0.236 - 134.4 1 2 0 -0.0003 14 0 0 0 0.00E+00 0.00E+00 - - - 1.5886 0.9343 230117_WJC_METTL3_WT_vs_EV_F02.21794.21794.2 2.54 12-Aug K.REGFFLK.S "sp|O75676|KS6A4_HUMAN,tr|E9PJN1|E9PJN1_HUMAN,tr|A0A0A6YYC0|A0A0A6YYC0_HUMAN" 3 895.4916 0.01 17551 21794 2 895.495031 448.7531 Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens OX=9606 GN=RPS6KA4 PE=1 SV=1 8.75 3940.1 - 534671 - - - 3.8448 - 1.313 0.006 - 199.2 1 2 0 0.0034 7 0 0 0 4.07E+06 5.96E+08 - - - -0.0529 0.9504 230117_WJC_METTL3_WT_vs_EV_F02.21796.21796.2 0.0165 12-Aug G.FGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 856.4847 -1 17552 21796 2 856.484465 429.2496 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3940.3 - 2.17E+06 - - - -0.2872 - 1.782 0.378 - 177.1 1 1 0 -0.0002 7 0 0 0 0.00E+00 0.00E+00 - - - 3.6634 1 230117_WJC_METTL3_WT_vs_EV_F02.21798.21798.2 1.59E-08 15/22 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 1312.35 17554 21798 2 1459.793514 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3940.4 - 2.64E+07 - - - 0.8686 - 3.113 0.574 - 1100.8 1 2 0 0.0013 12 0 0 0 7.49E+08 5.70E+05 - - - 6.2681 1 230117_WJC_METTL3_WT_vs_EV_F02.21799.21799.3 7.96E-06 15/60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 93.79 17555 21799 3 1796.007229 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3940.5 - 1.64E+07 - - - 1.5952 - 3.009 0.542 - 348.3 1 2 0 0.0029 16 0 0 0 1.35E+08 1.44E+06 - - - 7.4085 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21802.21802.2 4.93E-05 18-Nov K.FLLLQGLVEK.E "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 1158.7012 1.13 17558 21802 2 1158.702828 580.3579 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 6 3940.6 - 4.72E+06 - - - 1.3653 - 2.112 0.464 - 339.4 1 2 0 0.0016 10 0 0 0 1.47E+07 1.30E+07 - - - 4.5545 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21803.21803.3 4.13E-05 13/44 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 189.25 17559 21803 3 1459.793185 487.6047 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3940.6 - 3.47E+06 - - - 0.6432 - 2.69 0.418 - 349.6 1 2 0 0.0009 12 0 0 0 6.94E+07 3.67E+05 - - - 5.9429 1 230117_WJC_METTL3_WT_vs_EV_F02.21804.21804.2 0.00083 18/30 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 999 17560 21804 2 1796.007823 899.0095 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3940.7 - 3.30E+06 - - - 1.9259 - 3.767 0.607 - 1216.3 1 2 0 0.0035 16 0 0 0 3.02E+07 0.00E+00 - - - 6.7839 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.21805.21805.2 0.436 20-Oct K.LALGIPLPELR.N "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1190.7387 2.45 17561 21805 2 1190.739999 596.3766 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3940.8 - 2.62E+06 - - - 1.096 - 2.456 0.218 - 280.7 1 2 0 0.0013 11 0 0 0 3.04E+07 1.24E+07 - - - 3.0815 0.9905 230117_WJC_METTL3_WT_vs_EV_F02.21808.21808.2 0.0314 22-Aug K.YDNMAELFAVVK.T "sp|Q9UK41|VPS28_HUMAN,tr|E9PR04|E9PR04_HUMAN,tr|E9PQR7|E9PQR7_HUMAN,tr|E9PM90|E9PM90_HUMAN" 4 1398.6853 3.72 17564 21808 2 1398.686072 700.3499 Vacuolar protein sorting-associated protein 28 homolog OS=Homo sapiens OX=9606 GN=VPS28 PE=1 SV=1 4.37 3941 - 1.58E+06 - - - 0.5248 - 1.433 0.085 - 97.3 1 2 0 0.0007 12 0 0 0 5.25E+06 1.41E+06 - - - 0.6152 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.21810.21810.2 0.017 20-Oct R.TNLANVVLLLK[136.11].S sp|Q92620|PRP16_HUMAN 1 1204.7635 -1 17566 21810 2 1204.762959 603.389 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38 PE=1 SV=2 8.41 3941.1 - 1.09E+06 - - - -0.415 - 1.938 0.371 - 307 1 2 0 -0.0005 11 0 0 0 0.00E+00 0.00E+00 - - - 3.571 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.21812.21812.2 0.000197 13/24 K.WAIAQLNYADMLK.R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1535.7806 1.3 17568 21812 2 1535.778037 768.8976 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.83 3941.4 - 543960 - - - -1.6916 - 2.32 0.37 - 398.8 1 2 0 -0.0026 13 0 0 0 3.12E+06 2.41E+06 - - - 3.9329 0.9898 230117_WJC_METTL3_WT_vs_EV_F02.21820.21820.2 0.386 12-Jun K.ELFSFFR.D "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 944.4756 1.68 17574 21820 2 944.475018 473.2451 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6.1 3942.3 - 1.89E+06 - - - -0.6194 - 1.408 0.119 - 156 1 2 0 -0.0006 7 0 0 0 5.90E+06 3.51E+06 - - - 1.0039 1 230117_WJC_METTL3_WT_vs_EV_F02.21822.21822.2 7.33E-05 22-Oct K.ITVNEVELLVMK[136.11].A "sp|Q9UNM6|PSD13_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 2 1394.7934 1.62 17576 21822 2 1394.795644 698.404 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 4.53 3942.5 - 1.79E+06 - - - 1.5809 - 2.482 0.488 - 388.7 1 2 0 0.0022 12 0 0 0 1.41E+07 8.74E+06 - - - 5.0366 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21823.21823.2 1.4 22-Dec K.VLLVLELQGLQK.N sp|Q14697|GANAB_HUMAN 1 1351.8439 -1 17577 21823 2 1351.84484 676.9292 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 5.97 3942.6 - 1.57E+06 - - - 0.7042 - 2.437 0.424 - 393.9 1 2 0 0.001 12 0 0 0 0.00E+00 0.00E+00 - - - 4.5161 1 230117_WJC_METTL3_WT_vs_EV_F02.21824.21824.2 1.70E-06 18-Nov K.ADLTALFLPR[166.11].Q sp|Q13045|FLII_HUMAN 1 1125.6422 1.66 17578 21824 2 1125.644495 563.8284 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.88 3942.7 - 1.41E+06 - - - 2.0699 - 2.505 0.485 - 336.5 1 2 0 0.0023 10 0 0 0 1.32E+07 7.93E+06 - - - 5.1857 1 230117_WJC_METTL3_WT_vs_EV_F02.21825.21825.2 0.000517 22-Oct K.VLLVLELQGLQK[136.11].N sp|Q14697|GANAB_HUMAN 1 1359.8581 -1 17579 21825 2 1359.857197 680.9363 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 5.97 3942.8 - 1.23E+06 - - - -0.6552 - 2.26 0.522 - 268 1 2 0 -0.0009 12 0 0 0 0.00E+00 0.00E+00 - - - 5.0416 0.9931 230117_WJC_METTL3_WT_vs_EV_F02.21826.21826.2 1.02 12-Jun K.ELFSFFR[166.11].D "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 954.4839 1.68 17580 21826 2 954.483755 478.2492 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6.1 3943 - 1.20E+06 - - - -0.1236 - 1.351 0.146 - 148.4 1 2 0 -0.0001 7 0 0 0 5.90E+06 3.51E+06 - - - 1.0726 1 230117_WJC_METTL3_WT_vs_EV_F02.21830.21830.2 0.000123 20-Sep K.VVLPTFILEPR.S "sp|Q9BZF1|OSBL8_HUMAN,tr|F8VUA7|F8VUA7_HUMAN,tr|F8VQX7|F8VQX7_HUMAN" 3 1282.7649 2.59 17584 21830 2 1282.764314 642.3897 Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3 5.97 3943.5 - 844117 - - - -0.4638 - 2.107 0.493 - 299.7 1 2 0 -0.0006 11 0 0 0 5.03E+06 1.94E+06 - - - 4.6982 0.9979 230117_WJC_METTL3_WT_vs_EV_F02.21834.21834.2 0.241 Sep-36 R.QAAAAGPGTSGLAATR[166.11]PRR.W sp|Q03169|TNAP2_HUMAN 1 1817.9848 - 17588 21834 2 1817.988443 909.9997 Tumor necrosis factor alpha-induced protein 2 OS=Homo sapiens OX=9606 GN=TNFAIP2 PE=1 SV=2 12.3 3944 - 654528 - - - 2.0055 - 1.684 0.195 - 111.7 1 2 0 0.0036 19 0 0 0 - - - - - 1.7615 0.9402 230117_WJC_METTL3_WT_vs_EV_F02.21837.21837.3 0.0195 Oct-56 R.VLAFLSSVAGDALTR[166.11].H sp|Q92616|GCN1_HUMAN 1 1528.8489 0.71 17590 21837 3 1529.85052 510.6236 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3944.4 - 447795 - - - 655.1707 - 2.101 0.338 - 90.9 1 2 0 1.0017 15 0 0 0 2.66E+06 3.76E+06 - - - 3.9681 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21844.21844.2 0.000951 22-Oct R.VALILQNVDLPN.- "sp|Q04446|GLGB_HUMAN,tr|E9PGM4|E9PGM4_HUMAN" 2 1307.7449 - 17597 21844 2 1307.746512 654.8797 "1,4-alpha-glucan-branching enzyme OS=Homo sapiens OX=9606 GN=GBE1 PE=1 SV=3" 3.8 3944.8 - 2.06E+06 - - - 1.2311 - 2.006 0.439 - 211.2 1 2 0 0.0016 12 0 0 0 - - - - - 4.1146 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.21845.21845.2 0.0215 20-Oct K.AIVEFLSNLAR.H sp|Q13112|CAF1B_HUMAN 1 1231.6925 1.97 17598 21845 2 1231.693455 616.8535 Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1 6.05 3944.9 - 1.68E+06 - - - 0.7981 - 1.963 0.227 - 369 1 2 0 0.001 11 0 0 0 7.00E+06 3.55E+06 - - - 2.5419 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.21847.21847.2 0.0204 16-Oct R.DILALMEVK.M sp|Q96EK4|THA11_HUMAN 1 1030.5733 2.13 17600 21847 2 1030.574257 516.2939 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 4.37 3945.1 - 1.32E+06 - - - 0.9597 - 1.996 0.28 - 290.4 1 2 0 0.001 9 0 0 0 3.66E+06 1.71E+06 - - - 3.1083 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21849.21849.2 0.0054 13/24 R.NIIGVIPYFPYSK.Q "sp|Q14558|KPRA_HUMAN,tr|C9JKT9|C9JKT9_HUMAN,tr|B4DP31|B4DP31_HUMAN,tr|C9JNQ3|C9JNQ3_HUMAN,tr|C9JUN4|C9JUN4_HUMAN,tr|C9J168|C9J168_HUMAN" 6 1509.8232 -1 17602 21849 2 1509.824351 755.9189 Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Homo sapiens OX=9606 GN=PRPSAP1 PE=1 SV=2 8.5 3945.3 - 1.17E+06 - - - 0.7941 - 2.178 0.335 - 392.5 1 2 0 0.0012 13 0 0 0 0.00E+00 0.00E+00 - - - 3.5127 1 230117_WJC_METTL3_WT_vs_EV_F02.21850.21850.2 5.25E-07 14/20 K.TPVLFDIYEIK.E sp|P50995|ANX11_HUMAN 1 1336.7279 3.73 17603 21850 2 1336.727305 669.3712 Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1 4.37 3945.4 - 1.16E+06 - - - -0.4115 - 2.974 0.586 - 1130 1 2 0 -0.0006 11 0 0 0 4.68E+06 1.26E+06 - - - 6.3175 1 230117_WJC_METTL3_WT_vs_EV_F02.21854.21854.2 0.000303 24-Dec R.NIFPSNLVSAAFR.S "sp|Q15758|AAAT_HUMAN,tr|M0QXM4|M0QXM4_HUMAN,tr|M0QX44|M0QX44_HUMAN" 3 1434.7619 1.07 17607 21854 2 1434.766828 718.3883 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 9.75 3945.9 - 696658 - - - 3.4006 - 2.342 0.476 - 408.9 1 2 0 0.0049 13 0 0 0 5.48E+06 5.14E+06 - - - 4.7393 1 230117_WJC_METTL3_WT_vs_EV_F02.21856.21856.2 0.173 16/26 K.QIALAVLSTELAVR[166.11].K "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1492.8852 -1 17609 21856 2 1492.888298 747.4499 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3946.1 - 638871 - - - 2.0424 - 2.967 0.494 - 1006.5 1 2 0 0.003 14 0 0 0 0.00E+00 0.00E+00 - - - 5.4179 1 230117_WJC_METTL3_WT_vs_EV_F02.21859.21859.2 1.69E-05 18-Nov K.ADLTALFLPR.Q sp|Q13045|FLII_HUMAN 1 1115.6339 1.6 17611 21859 2 1115.635884 558.8242 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.88 3946.5 - 1.53E+06 - - - 1.7828 - 2.448 0.421 - 426.9 1 2 0 0.002 10 0 0 0 1.32E+07 8.20E+06 - - - 4.6489 1 230117_WJC_METTL3_WT_vs_EV_F02.21860.21860.2 0.00074 26-Dec K.LYSPSQIGAFVLMK.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1552.8323 5.49 17612 21860 2 1552.834896 777.4234 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3946.5 - 6.43E+06 - - - 1.648 - 2.534 0.545 - 421.3 1 2 0 0.0026 14 0 0 0 8.19E+07 1.49E+07 - - - 5.3989 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.21863.21863.2 7.06E-05 16-Sep R.NLPFDFTWK.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1166.576 3.05 17615 21863 2 1166.579735 584.2953 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3946.6 - 3.51E+06 - - - 3.1622 - 1.632 0.323 - 216.7 1 2 0 0.0037 9 0 0 0 1.75E+08 5.73E+07 - - - 2.8426 1 230117_WJC_METTL3_WT_vs_EV_F02.21866.21866.2 1.69E-07 20/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 4.64 17618 21866 2 1591.948703 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3946.9 - 1.83E+06 - - - 2.3267 - 3.206 0.575 - 1025.4 1 2 0 0.0037 15 0 0 0 1.32E+08 2.84E+07 - - - 6.1511 1 230117_WJC_METTL3_WT_vs_EV_F02.21867.21867.2 0.00334 20-Nov K.DFAPVIVEAFK.H "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1234.6598 1.98 17619 21867 2 1234.660309 618.3372 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.37 3946.9 - 1.74E+06 - - - 0.4325 - 2.225 0.515 - 358.1 1 2 0 0.0005 11 0 0 0 1.90E+07 9.55E+06 - - - 5.0082 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.21868.21868.3 0.0118 Dec-44 R.EGGFLLLHTLLR.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1367.7925 1.64 17620 21868 3 1367.794651 456.9381 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.85 3947 - 1.66E+06 - - - 1.5573 - 2.181 0.362 - 173.2 1 2 0 0.0021 12 0 0 0 4.40E+06 2.68E+06 - - - 4.7368 1 230117_WJC_METTL3_WT_vs_EV_F02.21871.21871.2 2.07E-05 15/28 R.VLAFLSSVAGDALTR[166.11].H sp|Q92616|GCN1_HUMAN 1 1528.8489 -1 17623 21871 2 1528.854512 765.4317 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3947.4 - 1.17E+06 - - - 3.6949 - 2.748 0.518 - 739.6 1 2 0 0.0056 15 0 0 0 0.00E+00 0.00E+00 - - - 5.3505 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21873.21873.3 1.33E-05 13/56 R.VLAFLSSVAGDALTR.H sp|Q92616|GCN1_HUMAN 1 1518.8406 -1 17625 21873 3 1518.843806 507.2875 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3947.6 - 1.15E+06 - - - 2.1154 - 2.42 0.471 - 217.3 1 2 0 0.0032 15 0 0 0 0.00E+00 0.00E+00 - - - 6.0964 1 230117_WJC_METTL3_WT_vs_EV_F02.21874.21874.2 0.000648 18-Nov R.LLELQYFISR[166.11].D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1290.7211 -1 17626 21874 2 1290.723643 646.3678 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 6 3947.7 - 1.10E+06 - - - 1.9369 - 2.432 0.451 - 512.5 1 2 0 0.0025 10 0 0 0 0.00E+00 0.00E+00 - - - 4.852 0.9988 230117_WJC_METTL3_WT_vs_EV_F02.21875.21875.2 0.000256 20-Nov K.DFAPVIVEAFK[136.11].H "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1242.674 -1 17627 21875 2 1242.671912 622.3443 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.37 3947.7 - 949073 - - - -1.6601 - 1.961 0.457 - 358.7 1 2 0 -0.0021 11 0 0 0 0.00E+00 0.00E+00 - - - 4.2376 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.21876.21876.2 0.00374 18-Dec R.LLELQYFISR.D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1280.7129 0.9 17628 21876 2 1280.717665 641.3637 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 6 3947.9 - 903929 - - - 3.7417 - 2.356 0.356 - 657.5 1 2 0 0.0048 10 0 0 0 6.42E+06 7.16E+06 - - - 4.061 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21877.21877.2 2.73E-05 20-Oct R.ELYLQVIQYMR[166.11].R sp|Q9BRS2|RIOK1_HUMAN 1 1464.7674 -1 17629 21877 2 1464.77 733.391 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 6.1 3948 - 1.26E+06 - - - 1.7464 - 2.048 0.453 - 381.8 1 2 0 0.0026 11 0 0 0 0.00E+00 0.00E+00 - - - 4.3253 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21880.21880.3 0.0712 Dec-44 R.EGGFLLLHTLLR[166.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1377.8008 -1 17631 21880 3 1377.803212 460.2742 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.85 3948.4 - 872405 - - - 1.7571 - 2.248 0.292 - 189.3 1 2 0 0.0024 12 0 0 0 0.00E+00 0.00E+00 - - - 4.0402 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21881.21881.3 2.10E-06 15/56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 4.77 17632 21881 3 1591.949709 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3948.4 - 7.53E+06 - - - 2.9586 - 2.576 0.518 - 211.5 1 2 0 0.0047 15 0 0 0 7.76E+07 1.63E+07 - - - 6.783 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21882.21882.3 2.79E-05 13/52 K.LYSPSQIGAFVLMK.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1552.8323 4.13 17633 21882 3 1552.83699 518.6181 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3948.4 - 4.90E+06 - - - 2.9965 - 2.496 0.498 - 283.6 1 2 0 0.0047 14 0 0 0 2.39E+07 5.78E+06 - - - 6.5217 1 230117_WJC_METTL3_WT_vs_EV_F02.21883.21883.3 5.03E-13 20/72 R.GPLLVQDVVFTDEMAHFDR.E sp|P04040|CATA_HUMAN 1 2188.0623 999 17634 21883 3 2188.068608 730.3614 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 4.22 3948.5 - 3.17E+06 - - - 2.8875 - 3.547 0.678 - 552.9 1 2 0 0.0063 19 0 0 0 1.74E+07 0.00E+00 - - - 9.2078 1 230117_WJC_METTL3_WT_vs_EV_F02.21884.21884.2 1.02E-10 15/28 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 4.64 17635 21884 2 1601.957635 801.9839 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3948.6 - 2.47E+06 - - - 2.7254 - 2.756 0.646 - 539.7 1 2 0 0.0044 15 0 0 0 1.32E+08 2.84E+07 - - - 6.3034 0.9958 230117_WJC_METTL3_WT_vs_EV_F02.21886.21886.2 1.05 14-Jul K.ISLIQIFR[166.11].A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 998.6152 -1 17637 21886 2 998.617558 500.3149 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.75 3948.7 - 1.57E+06 - - - 2.3392 - 1.696 0.108 - 128.7 2 2 0 0.0023 8 0 0 0 0.00E+00 0.00E+00 - - - 1.2967 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21888.21888.2 1.68E-05 22-Dec R.TLITFAGMIPYR.T "sp|Q8N1F7|NUP93_HUMAN,tr|H3BV15|H3BV15_HUMAN" 2 1381.7428 -1 17639 21888 2 1381.746183 691.8787 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 8.41 3948.9 - 1.10E+06 - - - 2.4534 - 2.543 0.319 - 520.4 1 2 0 0.0034 12 0 0 0 0.00E+00 0.00E+00 - - - 3.8519 1 230117_WJC_METTL3_WT_vs_EV_F02.21889.21889.2 1.82E-05 22-Nov K.LLPLVSDEVFIR.D sp|P11216|PYGB_HUMAN 1 1399.8075 10.31 17640 21889 2 1399.810384 700.911 "Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB PE=1 SV=5" 4.37 3949 - 1.07E+06 - - - 2.0589 - 2.28 0.54 - 418.5 1 2 0 0.0029 12 0 0 0 4.47E+06 4.34E+05 - - - 5.1971 1 230117_WJC_METTL3_WT_vs_EV_F02.21890.21890.2 9.36E-09 16/32 R.AIGLSPMSFPTADLTLK.M "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1760.9383 -1 17641 21890 2 1760.941706 881.4764 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.88 3949.2 - 981091 - - - 1.958 - 3.238 0.504 - 742 1 2 0 0.0034 17 0 0 0 0.00E+00 0.00E+00 - - - 5.6511 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21892.21892.3 2.34 14/52 K.LAGLVEELEADEWR.F "sp|Q96DE5|APC16_HUMAN,tr|A0A087WUN5|A0A087WUN5_HUMAN" 2 1628.8046 -1 17643 21892 3 1628.808746 543.9421 Anaphase-promoting complex subunit 16 OS=Homo sapiens OX=9606 GN=ANAPC16 PE=1 SV=1 3.91 3949.4 - 742673 - - - 2.5442 - 2.77 0.402 - 390.9 1 2 0 0.0041 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7284 1 230117_WJC_METTL3_WT_vs_EV_F02.21894.21894.2 1.67E-08 17/32 R.AIGLSPMSFPTADLTLK[136.11].M "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1768.9525 -1 17645 21894 2 1768.956408 885.4835 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.88 3949.6 - 684092 - - - 2.233 - 3.178 0.588 - 924.7 1 2 0 0.004 17 0 0 0 0.00E+00 0.00E+00 - - - 6.2254 0.998 230117_WJC_METTL3_WT_vs_EV_F02.21900.21900.2 0.132 26-Dec K.LAGLVEELEADEWR[166.11].F "sp|Q96DE5|APC16_HUMAN,tr|A0A087WUN5|A0A087WUN5_HUMAN" 2 1638.8129 -1 17650 21900 2 1638.817971 820.4137 Anaphase-promoting complex subunit 16 OS=Homo sapiens OX=9606 GN=ANAPC16 PE=1 SV=1 3.91 3950.3 - 373743 - - - 3.1114 - 1.952 0.22 - 428.9 1 2 0 0.0051 14 0 0 0 0.00E+00 0.00E+00 - - - 2.3428 1 230117_WJC_METTL3_WT_vs_EV_F02.21903.21903.2 1.73E-05 26-Dec K.LYSPSQIGAFVLMK[136.11].M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1560.8465 5.49 17653 21903 2 1560.849813 781.4305 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3950.5 - 5.14E+06 - - - 2.0989 - 2.572 0.527 - 419.9 1 2 0 0.0033 14 0 0 0 8.19E+07 1.49E+07 - - - 5.303 0.9982 230117_WJC_METTL3_WT_vs_EV_F02.21904.21904.2 5.36E-05 16-Oct R.NLPFDFTWK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1174.5902 3.04 17654 21904 2 1174.587366 588.3024 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3950.6 - 4.81E+06 - - - -2.4519 - 1.817 0.495 - 297.1 1 2 0 -0.0029 9 0 0 0 1.74E+08 5.73E+07 - - - 4.4239 1 230117_WJC_METTL3_WT_vs_EV_F02.21905.21905.3 8.66E-05 14/56 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 4.77 17655 21905 3 1601.956359 534.9917 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3950.6 - 2.55E+06 - - - 1.9289 - 2.855 0.493 - 181 1 2 0 0.0031 15 0 0 0 7.76E+07 1.63E+07 - - - 6.773 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21906.21906.3 0.000161 Oct-52 K.LYSPSQIGAFVLMK[136.11].M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1560.8465 4.16 17656 21906 3 1560.849802 521.2895 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3950.7 - 2.08E+06 - - - 2.0918 - 2.275 0.406 - 174.1 1 2 0 0.0033 14 0 0 0 2.40E+07 5.78E+06 - - - 5.25 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.21907.21907.2 1.32 18-Aug K.VLLDIFTGVR.L sp|P49916|DNLI3_HUMAN 1 1131.6652 -1 17657 21907 2 1131.667675 566.8399 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 5.81 3950.8 - 1.86E+06 - - - 2.1915 - 1.865 0.181 - 147.1 1 2 0 0.0025 10 0 0 0 0.00E+00 0.00E+00 - - - 2.1168 1 230117_WJC_METTL3_WT_vs_EV_F02.21910.21910.2 2.96E-12 13/26 R.FGDPEC[160.03]QVILPLLK.S sp|P22102|PUR2_HUMAN 1 1627.8644 1.2 17660 21910 2 1627.867942 814.9395 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.37 3951 - 1.27E+06 - - - 2.1974 - 3.166 0.683 - 492.1 1 2 0 0.0036 14 0 0 0 4.64E+06 3.87E+06 - - - 6.9766 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21913.21913.2 0.0054 18-Dec K.LLELQELVLR.L "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|A0A087WYC0|A0A087WYC0_HUMAN" 3 1224.7442 -1 17663 21913 2 1224.747426 613.3794 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 4.53 3951.4 - 1.06E+06 - - - 2.6552 - 2.514 0.304 - 475.6 1 2 0 0.0033 10 0 0 0 0.00E+00 0.00E+00 - - - 3.8586 1 230117_WJC_METTL3_WT_vs_EV_F02.21914.21914.2 0.00016 14/28 K.LDLSVTEAVVAGIAK.A sp|P22102|PUR2_HUMAN 1 1484.845 -1 17664 21914 2 1484.849169 743.4298 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.37 3951.4 - 1.03E+06 - - - 2.801 - 2.3 0.556 - 500 1 2 0 0.0042 15 0 0 0 0.00E+00 0.00E+00 - - - 5.1941 1 230117_WJC_METTL3_WT_vs_EV_F02.21915.21915.2 2.11E-06 18/24 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 -1 17665 21915 2 1509.891343 755.9512 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3951.6 - 1.02E+06 - - - 2.2949 - 3.003 0.584 - 1121 1 2 0 0.0035 13 0 0 0 0.00E+00 0.00E+00 - - - 6.1755 1 230117_WJC_METTL3_WT_vs_EV_F02.21916.21916.2 3.24E-10 15/24 K.MFVLDEADEMLSR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 11 1564.7141 -1 17666 21916 2 1564.717709 783.3643 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 3.92 3951.6 - 1.01E+06 - - - 2.3154 - 2.851 0.597 - 694 1 2 0 0.0036 13 0 0 0 0.00E+00 0.00E+00 - - - 6.1382 1 230117_WJC_METTL3_WT_vs_EV_F02.21918.21918.2 1.56E-05 16/24 R.IGLFYMDNDLITR.N "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN" 2 1569.7861 -1 17668 21918 2 1569.789485 785.9003 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.21 3951.8 - 772434 - - - 2.1468 - 3.131 0.543 - 1178.8 1 2 0 0.0034 13 0 0 0 0.00E+00 0.00E+00 - - - 5.9799 0.997 230117_WJC_METTL3_WT_vs_EV_F02.21919.21919.2 0.00896 15/28 R.ALVEVLGPYEPLLSR.V "sp|Q86VR2|RETR3_HUMAN,tr|K7EMF4|K7EMF4_HUMAN,tr|K7ELM8|K7ELM8_HUMAN,tr|K7EJ34|K7EJ34_HUMAN,tr|K7ENF4|K7ENF4_HUMAN,tr|K7ENZ6|K7ENZ6_HUMAN" 6 1654.9294 1.57 17669 21919 2 1654.938614 828.472 Reticulophagy regulator 3 OS=Homo sapiens OX=9606 GN=RETREG3 PE=1 SV=1 4.53 3952 - 723903 - - - 5.5628 - 3.029 0.327 - 640.2 1 2 0 0.0092 15 0 0 0 3.18E+06 2.02E+06 - - - 4.178 1 230117_WJC_METTL3_WT_vs_EV_F02.21922.21922.2 1.01E-07 24-Dec R.IGLFYMDNDLITR[166.11].N "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN" 2 1579.7944 -1 17671 21922 2 1579.801315 790.9045 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.21 3952.2 - 1.38E+06 - - - 4.3866 - 2.364 0.543 - 511.3 1 2 0 0.0069 13 0 0 0 0.00E+00 0.00E+00 - - - 5.2575 1 230117_WJC_METTL3_WT_vs_EV_F02.21923.21923.2 0.000313 13/24 R.NVIVLQTVLQEVR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1519.8961 -1 17672 21923 2 1519.897946 760.9554 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3952.3 - 6.76E+06 - - - 1.183 - 2.715 0.515 - 609.8 1 2 0 0.0018 13 0 0 0 0.00E+00 0.00E+00 - - - 5.4077 1 230117_WJC_METTL3_WT_vs_EV_F02.21925.21925.3 3.92E-06 15/48 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 -1 17674 21925 3 1509.88949 504.3032 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3952.4 - 3.43E+06 - - - 1.0676 - 2.965 0.597 - 413.9 1 2 0 0.0016 13 0 0 0 0.00E+00 0.00E+00 - - - 8.1424 1 230117_WJC_METTL3_WT_vs_EV_F02.21926.21926.3 8.40E-07 14/48 R.NVIVLQTVLQEVR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1519.8961 -1 17675 21926 3 1519.897674 507.6393 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3952.4 - 1.42E+06 - - - 1.004 - 2.769 0.524 - 324.6 1 2 0 0.0015 13 0 0 0 0.00E+00 0.00E+00 - - - 7.1431 1 230117_WJC_METTL3_WT_vs_EV_F02.21929.21929.2 4.24E-06 26-Dec K.LSPVVGAVYGPELY.A "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 7 1462.7708 - 17678 21929 2 1462.769948 732.3927 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4 3952.6 - 1.18E+06 - - - -0.5702 - 2.173 0.516 - 401.3 1 1 0 -0.0008 14 0 0 0 - - - - - 4.7995 1 230117_WJC_METTL3_WT_vs_EV_F02.21932.21932.2 8.86E-08 22-Dec R.VFLALVEEVEDR.G "sp|Q9H3U1|UN45A_HUMAN,tr|A0A1W2PNX8|A0A1W2PNX8_HUMAN" 2 1417.7453 -1 17681 21932 2 1417.747262 709.8799 Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1 4 3952.8 - 928313 - - - 1.3867 - 2.481 0.562 - 304.4 1 2 0 0.002 12 0 0 0 0.00E+00 0.00E+00 - - - 5.5822 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.21933.21933.2 0.000243 20-Dec K.DTLTYFIYSVK.N sp|O75446|SAP30_HUMAN 1 1348.6915 2.4 17682 21933 2 1348.691345 675.353 Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1 5.83 3952.9 - 848504 - - - -0.0919 - 2.146 0.302 - 601.9 1 2 0 -0.0001 11 0 0 0 3.47E+06 1.45E+06 - - - 3.3373 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21935.21935.2 0.000748 22-Dec R.VFLALVEEVEDR[166.11].G "sp|Q9H3U1|UN45A_HUMAN,tr|A0A1W2PNX8|A0A1W2PNX8_HUMAN" 2 1427.7536 -1 17684 21935 2 1427.755137 714.8841 Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1 4 3953.1 - 782843 - - - 1.1003 - 2.3 0.406 - 567.9 1 2 0 0.0016 12 0 0 0 0.00E+00 0.00E+00 - - - 4.2307 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21936.21936.2 0.000966 28-Sep R.ALVEVLGPYEPLLSR[166.11].V "sp|Q86VR2|RETR3_HUMAN,tr|K7EMF4|K7EMF4_HUMAN,tr|K7ELM8|K7ELM8_HUMAN,tr|K7EJ34|K7EJ34_HUMAN,tr|K7ENF4|K7ENF4_HUMAN,tr|K7ENZ6|K7ENZ6_HUMAN" 6 1664.9377 1.57 17685 21936 2 1664.938576 833.4761 Reticulophagy regulator 3 OS=Homo sapiens OX=9606 GN=RETREG3 PE=1 SV=1 4.53 3953.2 - 743811 - - - 0.5394 - 2.281 0.368 - 208.6 1 2 0 0.0009 15 0 0 0 3.18E+06 2.02E+06 - - - 3.7861 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21939.21939.2 0.00506 16-Oct K.ILNIFGVIK[136.11].G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1023.6572 1.32 17688 21939 2 1023.659166 512.8359 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3953.5 - 627080 - - - 1.9176 - 2.057 0.304 - 237.1 1 2 0 0.002 9 0 0 0 1.36E+07 1.03E+07 - - - 3.3723 1 230117_WJC_METTL3_WT_vs_EV_F02.21943.21943.2 1.01E-06 17/32 R.LTSIIFAEDITTGQVLR.C sp|Q8TEM1|PO210_HUMAN 1 1876.0306 -1 17691 21943 2 1876.030938 939.0226 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.37 3954 - 325749 - - - 0.1914 - 3.469 0.681 - 850.9 1 2 0 0.0004 17 0 0 0 0.00E+00 0.00E+00 - - - 7.1289 1 230117_WJC_METTL3_WT_vs_EV_F02.21944.21944.3 7.56E-08 15/48 K.LFYADHPFIFLVR.D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1636.8766 3.17 17692 21944 3 1636.878042 546.6328 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3954 - 1.13E+07 - - - 0.8901 - 2.726 0.588 - 254.8 1 2 0 0.0015 13 0 0 0 4.77E+07 1.51E+07 - - - 7.8142 1 230117_WJC_METTL3_WT_vs_EV_F02.21945.21945.2 2.88E-05 20-Oct K.SVFGGLVNYFK.S "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1229.6445 -1 17693 21945 2 1229.645374 615.8295 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 8.31 3954.1 - 6.16E+06 - - - 0.7441 - 2.005 0.506 - 260 1 2 0 0.0009 11 0 0 0 0.00E+00 0.00E+00 - - - 4.6599 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.21946.21946.2 0.0667 16-Sep K.ILNIFGVIK.G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1015.643 -1 17694 21946 2 1015.643924 508.8288 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3954.1 - 6.15E+06 - - - 0.9068 - 1.901 0.332 - 185.4 1 2 0 0.0009 9 0 0 0 0.00E+00 0.00E+00 - - - 3.3513 1 230117_WJC_METTL3_WT_vs_EV_F02.21948.21948.3 2.04E-08 16/48 K.LFYADHPFIFLVR[166.11].D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1646.8849 3.17 17696 21948 3 1646.886414 549.9689 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3954.2 - 3.46E+06 - - - 0.9466 - 3.278 0.586 - 273.7 1 2 0 0.0016 13 0 0 0 4.77E+07 1.51E+07 - - - 8.2918 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.21949.21949.3 0.04 Nov-40 K.ILDVEIIFNER.G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1359.7398 -1 17697 21949 3 1359.739199 454.2539 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3954.3 - 3.40E+06 - - - -0.4545 - 1.998 0.293 - 229.5 1 2 0 -0.0006 11 0 0 0 0.00E+00 0.00E+00 - - - 3.7728 1 230117_WJC_METTL3_WT_vs_EV_F02.21950.21950.2 5.23E-05 20-Nov K.SVFGGLVNYFK[136.11].S "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1237.6587 -1 17698 21950 2 1237.659583 619.8366 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 8.31 3954.3 - 2.98E+06 - - - 0.7466 - 2.131 0.483 - 308.4 1 2 0 0.0009 11 0 0 0 0.00E+00 0.00E+00 - - - 4.6549 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.21951.21951.3 0.015 13/40 K.ILDVEIIFNER[166.11].G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1369.7481 -1 17699 21951 3 1369.749057 457.59 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3954.4 - 2.61E+06 - - - 0.7082 - 2.32 0.328 - 326 1 2 0 0.001 11 0 0 0 0.00E+00 0.00E+00 - - - 4.5874 1 230117_WJC_METTL3_WT_vs_EV_F02.21952.21952.2 0.000248 13/22 R.NMLQFNLQILPK.S "sp|O15371|EIF3D_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 3 1457.8065 -1 17700 21952 2 1457.80832 729.9105 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 8.75 3954.5 - 2.24E+06 - - - 1.2786 - 2.541 0.496 - 636.5 1 2 0 0.0019 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1576 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.21953.21953.2 0.632 22-Dec K.IVILPDYLEIAR.D sp|P45974|UBP5_HUMAN 1 1413.8232 -1 17701 21953 2 1413.823164 707.9189 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 4.37 3954.5 - 2.22E+06 - - - 0.0085 - 2.247 0.407 - 457.1 1 2 0 0 12 0 0 0 0.00E+00 0.00E+00 - - - 4.1773 1 230117_WJC_METTL3_WT_vs_EV_F02.21955.21955.2 1.34E-06 26-Oct R.IVEPYVTWGFPNLK.S "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1661.8817 1.24 17703 21955 2 1661.885236 831.9481 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6 3954.7 - 1.63E+06 - - - 2.1097 - 2.268 0.558 - 264.6 1 2 0 0.0035 14 0 0 0 5.17E+06 4.18E+06 - - - 5.2163 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21956.21956.2 9.90E-05 20-Nov R.SFIAEMTIYIK.Q sp|Q08211|DHX9_HUMAN 1 1314.6894 -1 17704 21956 2 1314.690729 658.352 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.72 3954.8 - 1.39E+06 - - - 1.0405 - 2.142 0.46 - 355.3 1 2 0 0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 4.4988 1 230117_WJC_METTL3_WT_vs_EV_F02.21957.21957.2 7.16E-09 13/26 R.IVEPYVTWGFPNLK[136.11].S "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1669.8959 -1 17705 21957 2 1669.899593 835.9552 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6 3954.9 - 1.26E+06 - - - 2.1935 - 2.481 0.599 - 471.7 1 2 0 0.0037 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7443 1 230117_WJC_METTL3_WT_vs_EV_F02.21958.21958.2 0.00103 13/24 R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 17706 21958 2 1349.790741 675.9026 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3955 - 1.25E+06 - - - 0.0896 - 2.612 0.48 - 522.1 1 2 0 0.0001 13 0 0 0 0.00E+00 0.00E+00 - - - 5.0504 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.21959.21959.2 0.000216 24-Nov R.ILPSLEDTLSLVK.R "sp|Q9NX74|DUS2L_HUMAN,tr|E7EUN9|E7EUN9_HUMAN,tr|J3QLD5|J3QLD5_HUMAN" 3 1426.8283 -1 17707 21959 2 1426.834451 714.4214 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like OS=Homo sapiens OX=9606 GN=DUS2 PE=1 SV=1 4.37 3955.1 - 1.05E+06 - - - 4.3131 - 1.949 0.42 - 276.8 1 2 0 0.0062 13 0 0 0 0.00E+00 0.00E+00 - - - 3.8539 0.8602 230117_WJC_METTL3_WT_vs_EV_F02.21964.21964.2 4.28 22-Nov K.ALFNAQFGSIFR[166.11].T sp|Q9H857|NT5D2_HUMAN 1 1379.7225 0.001 17711 21964 2 1379.721067 690.8685 5'-nucleotidase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=NT5DC2 PE=1 SV=1 9.79 3955.7 - 891881 - - - -1.0676 - 1.052 0.024 - 182.7 1 2 0 -0.0015 12 0 0 0 0.00E+00 8.68E+06 - - - -0.6488 1 230117_WJC_METTL3_WT_vs_EV_F02.21965.21965.2 1.68E-05 14/20 K.ILDVEIIFNER[166.11].G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1369.7481 1.24 17712 21965 2 1369.750866 685.8813 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3955.8 - 1.65E+07 - - - 2.0288 - 2.637 0.523 - 1001.7 1 2 0 0.0028 11 0 0 0 7.45E+07 6.03E+07 - - - 5.5261 1 230117_WJC_METTL3_WT_vs_EV_F02.21970.21970.2 0.00269 13/22 K.SLVALLVETQMK.K "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1330.753 -1 17717 21970 2 1330.755787 666.3838 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.72 3956.1 - 2.69E+06 - - - 2.0763 - 2.712 0.443 - 615.1 1 2 0 0.0028 12 0 0 0 0.00E+00 0.00E+00 - - - 4.9372 1 230117_WJC_METTL3_WT_vs_EV_F02.21971.21971.2 8.87E-07 16/24 K.LGAGTFQLDQWLR.A sp|P50219|MNX1_HUMAN 1 1503.7834 -1 17718 21971 2 1503.786251 752.899 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 5.84 3956.1 - 2.03E+06 - - - 1.8872 - 3.076 0.526 - 946 1 2 0 0.0028 13 0 0 0 0.00E+00 0.00E+00 - - - 5.809 0.9782 230117_WJC_METTL3_WT_vs_EV_F02.21972.21972.3 0.000882 13/48 R.VNILEVASGAVLR.S sp|Q12788|TBL3_HUMAN 1 1339.7823 -1 17719 21972 3 1339.783546 447.6014 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3956.2 - 2.00E+06 - - - 0.8927 - 2.41 0.02 - 267.5 2 2 0 0.0012 13 0 0 0 0.00E+00 0.00E+00 - - - 1.0083 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.21974.21974.2 3.88E-05 18-Sep R.LGIYTVLFER.L "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 1209.6758 -1 17721 21974 2 1209.680574 605.8452 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 6 3956.4 - 1.83E+06 - - - 3.9796 - 2.121 0.448 - 226.9 1 2 0 0.0048 10 0 0 0 0.00E+00 0.00E+00 - - - 4.4472 0.9857 230117_WJC_METTL3_WT_vs_EV_F02.21975.21975.2 0.0501 20-Sep K.FVSISDLLVPK[136.11].D sp|P50395|GDIB_HUMAN 1 1224.7209 -1 17722 21975 2 1224.717099 613.3677 Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2 5.84 3956.5 - 1.77E+06 - - - -3.124 - 1.447 0.273 - 134.8 1 2 0 -0.0038 11 0 0 0 0.00E+00 0.00E+00 - - - 2.0557 0.999 230117_WJC_METTL3_WT_vs_EV_F02.21976.21976.2 0.0142 14-Sep R.TLFLELIR.A sp|Q96GM8|TOE1_HUMAN 1 1003.6066 1.9 17723 21976 2 1003.60772 502.8106 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 5.66 3956.5 - 1.70E+06 - - - 1.099 - 1.706 0.24 - 329.8 1 2 0 0.0011 8 0 0 0 5.09E+06 2.68E+06 - - - 2.4243 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21977.21977.3 0.000103 Dec-48 R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 17724 21977 3 1349.792534 450.9375 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3956.6 - 1.46E+06 - - - 1.418 - 2.727 0.401 - 261.8 1 2 0 0.0019 13 0 0 0 0.00E+00 0.00E+00 - - - 5.7302 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21978.21978.3 2.95E-06 14/48 K.FDTPFLPKPLFFR.R sp|Q14684|RRP1B_HUMAN 1 1623.8813 -1 17725 21978 3 1623.881611 542.3011 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 8.75 3956.7 - 1.43E+06 - - - 0.1693 - 2.484 0.475 - 159.4 1 2 0 0.0003 13 0 0 0 0.00E+00 0.00E+00 - - - 6.3026 1 230117_WJC_METTL3_WT_vs_EV_F02.21980.21980.2 0.000284 16/26 K.LDDIFEPVLIPEPK.L "sp|Q14008|CKAP5_HUMAN,tr|H0YEK7|H0YEK7_HUMAN,tr|H0YCF6|H0YCF6_HUMAN" 3 1623.876 -1 17727 21980 2 1623.879669 812.9453 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 3.92 3956.9 - 1.20E+06 - - - 2.2742 - 2.742 0.545 - 762.9 1 2 0 0.0037 14 0 0 0 0.00E+00 0.00E+00 - - - 5.5965 0.9826 230117_WJC_METTL3_WT_vs_EV_F02.21981.21981.2 0.214 20-Jun K.ATLWYVPLSLK[136.11].N "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1297.7526 1.27 17728 21981 2 1297.756147 649.8836 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 8.63 3957 - 1.18E+06 - - - 2.764 - 1.289 0.092 - 96.9 1 2 0 0.0036 11 0 0 0 3.99E+06 3.15E+06 - - - 0.4062 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.21984.21984.2 0.000576 28-Sep K.YFDTVPVAAAMC[160.03]VLK[136.11].T sp|Q15393|SF3B3_HUMAN 1 1691.8506 -1 17730 21984 2 1691.852103 846.9326 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.83 3957.4 - 271140 - - - 0.8671 - 1.709 0.314 - 177.2 1 2 0 0.0015 15 0 0 0 0.00E+00 0.00E+00 - - - 2.6773 0.9557 230117_WJC_METTL3_WT_vs_EV_F02.21987.21987.2 1.75 20-Jul R.VTWEPAPGEVK.G "sp|Q99715|COCA1_HUMAN,tr|D6RGG3|D6RGG3_HUMAN" 2 1211.6186 2179.69 17733 21987 2 1211.616943 606.8166 Collagen alpha-1(XII) chain OS=Homo sapiens OX=9606 GN=COL12A1 PE=1 SV=2 4.53 3957.6 - 1.19E+07 - - - -1.3998 - 1.332 0.064 - 174.8 1 2 0 -0.0017 11 0 0 0 4.54E+08 2.08E+05 - - - 0.2887 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21989.21989.2 0.000448 20-Nov K.LILPELGPVFK[136.11].Q "sp|Q6P3W7|SCYL2_HUMAN,tr|H0YIK6|H0YIK6_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 1232.7624 0.67 17735 21989 2 1232.763163 617.3885 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6 3957.7 - 7.36E+06 - - - 0.6222 - 1.791 0.479 - 376.2 1 2 0 0.0008 11 0 0 0 3.18E+07 4.74E+07 - - - 4.1552 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.21990.21990.2 0.00283 20-Nov K.GFLSGLLDNVK.Q "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1161.6394 2.68 17736 21990 2 1161.640375 581.827 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.84 3957.7 - 5.39E+06 - - - 0.8617 - 2.341 0.358 - 354.5 1 2 0 0.001 11 0 0 0 4.36E+07 1.63E+07 - - - 3.9859 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.21991.21991.2 0.0104 20-Sep K.FVSISDLLVPK.D sp|P50395|GDIB_HUMAN 1 1216.7067 4.47 17737 21991 2 1216.707361 609.3606 Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2 5.84 3957.8 - 4.64E+06 - - - 0.5227 - 1.58 0.368 - 174.7 1 2 0 0.0006 11 0 0 0 1.20E+07 2.68E+06 - - - 2.9963 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.21993.21993.2 0.000444 24-Dec K.LAGFLDLTEQEFR[166.11].L "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 1547.7859 1.48 17739 21993 2 1547.793737 774.9002 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.14 3957.8 - 4.17E+06 - - - 5.0446 - 2.296 0.299 - 482.3 1 2 0 0.0078 13 0 0 0 4.55E+07 3.08E+07 - - - 3.3802 1 230117_WJC_METTL3_WT_vs_EV_F02.21994.21994.3 9.58E-06 17/60 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 1.51 17740 21994 3 1663.952388 555.6576 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3957.9 - 3.13E+06 - - - 0.9111 - 3.295 0.514 - 286.5 1 2 0 0.0015 16 0 0 0 1.12E+07 7.46E+06 - - - 7.3297 1 230117_WJC_METTL3_WT_vs_EV_F02.21995.21995.3 1.35E-08 17/60 K.INEAIVAVQAIIADPK[136.11].T sp|Q9Y224|RTRAF_HUMAN 1 1671.9651 -1 17741 21995 3 1671.967013 558.329 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3957.9 - 2.76E+06 - - - 1.1609 - 3.102 0.557 - 239.3 1 2 0 0.0019 16 0 0 0 0.00E+00 0.00E+00 - - - 7.6541 1 230117_WJC_METTL3_WT_vs_EV_F02.21996.21996.2 0.00468 22-Dec K.SLVALLVETQMK[136.11].K "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1338.7672 -1 17742 21996 2 1338.767696 670.3909 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.72 3958 - 2.16E+06 - - - 0.3526 - 2.635 0.445 - 603.9 1 2 0 0.0005 12 0 0 0 0.00E+00 0.00E+00 - - - 4.8769 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.21997.21997.3 0.0008 14/48 R.IESILMSLPLTAR.W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1442.8167 1.37 17743 21997 3 1442.817365 481.9462 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3958.1 - 1.85E+06 - - - 0.4699 - 2.649 0.411 - 248.5 1 2 0 0.0007 13 0 0 0 7.72E+06 5.62E+06 - - - 5.7633 0.9927 230117_WJC_METTL3_WT_vs_EV_F02.21998.21998.2 0.568 24-Jul K.AFTYSSTLISHK[136.11]R[166.11].L sp|A8MUV8|ZN727_HUMAN 1 1527.8164 0.02 17744 21998 2 1527.819398 764.9155 Putative zinc finger protein 727 OS=Homo sapiens OX=9606 GN=ZNF727 PE=5 SV=3 9.99 3958.1 - 1.75E+06 - - - 1.9315 - 1.083 0.205 - 88.2 1 2 0 0.0029 13 0 0 0 9.74E+05 5.41E+07 - - - 0.7588 1 230117_WJC_METTL3_WT_vs_EV_F02.21999.21999.2 7.60E-10 19/30 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 -1 17745 21999 2 1663.952522 832.9827 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3958.2 - 1.55E+06 - - - 0.9916 - 3.733 0.489 - 1367.7 1 2 0 0.0016 16 0 0 0 0.00E+00 0.00E+00 - - - 5.8907 1 230117_WJC_METTL3_WT_vs_EV_F02.22000.22000.2 3.04E-06 13/22 R.ANLGVFSVFAPR[166.11].G "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1286.7011 1 17746 22000 2 1286.702106 644.3578 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 9.79 3958.3 - 1.42E+06 - - - 0.7997 - 2.527 0.478 - 651.5 1 2 0 0.001 12 0 0 0 7.54E+06 7.55E+06 - - - 5.0104 1 230117_WJC_METTL3_WT_vs_EV_F02.22001.22001.2 9.11E-08 16/30 K.INEAIVAVQAIIADPK[136.11].T sp|Q9Y224|RTRAF_HUMAN 1 1671.9651 -1 17747 22001 2 1671.963903 836.9898 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3958.4 - 1.31E+06 - - - -0.6992 - 3.255 0.484 - 710.6 1 2 0 -0.0012 16 0 0 0 0.00E+00 0.00E+00 - - - 5.517 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22003.22003.2 0.00696 20-Nov K.DVLLPWYNAYR.F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1408.7139 -1 17749 22003 2 1408.716923 705.3642 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3958.6 - 1.14E+06 - - - 2.1204 - 2.23 0.444 - 408.7 1 2 0 0.003 11 0 0 0 0.00E+00 0.00E+00 - - - 4.4891 1 230117_WJC_METTL3_WT_vs_EV_F02.22007.22007.2 4.11E-05 18-Oct K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 111.28 17752 22007 2 1146.628262 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3958.9 - 1.33E+07 - - - -0.1858 - 2.145 0.483 - 283.7 1 2 0 -0.0002 10 0 0 0 9.11E+07 8.19E+05 - - - 4.7385 1 230117_WJC_METTL3_WT_vs_EV_F02.22010.22010.2 1.01E-14 22/34 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 7.41 17755 22010 2 1911.946549 956.9806 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3959.1 - 8.50E+06 - - - -0.0136 - 4.178 0.644 - 1864.9 1 2 0 0 18 0 0 0 7.91E+07 1.07E+07 - - - 7.3129 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.22011.22011.2 0.00255 14/24 R.IESILMSLPLTAR[166.11].W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1452.825 1.26 17756 22011 2 1452.824736 727.4198 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3959.1 - 6.07E+06 - - - -0.1521 - 2.686 0.311 - 900.7 1 2 0 -0.0002 13 0 0 0 2.16E+07 1.71E+07 - - - 3.8738 0.9953 230117_WJC_METTL3_WT_vs_EV_F02.22017.22017.3 0.00414 Oct-48 R.IESILMSLPLTAR[166.11].W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1452.825 1.37 17762 22017 3 1452.820819 485.2823 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3959.4 - 2.12E+06 - - - -2.8482 - 2.026 0.285 - 158.5 1 2 0 -0.0041 13 0 0 0 7.72E+06 5.62E+06 - - - 3.6307 1 230117_WJC_METTL3_WT_vs_EV_F02.22018.22018.2 1.87E-05 20-Nov K.DVLLPWYNAYR[166.11].F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1418.7222 2.47 17763 22018 2 1418.718393 710.3684 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3959.5 - 2.11E+06 - - - -2.6876 - 2.137 0.566 - 422.6 1 2 0 -0.0038 11 0 0 0 1.76E+07 7.13E+06 - - - 5.2746 1 230117_WJC_METTL3_WT_vs_EV_F02.22019.22019.2 0.00441 22-Nov K.GVNSYPSLFIFR.S "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0TB22|A0A7P0TB22_HUMAN,tr|A0A7P0Z4F2|A0A7P0Z4F2_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN,tr|E7EP04|E7EP04_HUMAN,tr|A0A7P0T9B7|A0A7P0T9B7_HUMAN,tr|A0A494C1G5|A0A494C1G5_HUMAN,tr|A0A7P0TB83|A0A7P0TB83_HUMAN" 10 1398.7296 2.19 17764 22019 2 1398.731141 700.3721 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 8.75 3959.6 - 1.81E+06 - - - 1.1117 - 2.506 0.464 - 280.5 1 2 0 0.0016 12 0 0 0 1.67E+07 7.62E+06 - - - 4.8848 1 230117_WJC_METTL3_WT_vs_EV_F02.22022.22022.2 4.25E-12 22/34 K.LGGSLADSYLDEGFLLDK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1919.9608 -1 17767 22022 2 1919.960432 960.9877 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3959.9 - 1.17E+06 - - - -0.1786 - 4.233 0.635 - 2026 1 2 0 -0.0003 18 0 0 0 0.00E+00 0.00E+00 - - - 7.2785 1 230117_WJC_METTL3_WT_vs_EV_F02.22028.22028.2 1.22E-09 15/26 K.VVIGMDVAASEFFR.S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1539.7756 2.51 17772 22028 2 1539.773745 770.8951 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.37 3960.6 - 1.17E+07 - - - -1.1722 - 3.076 0.672 - 770.9 1 2 0 -0.0018 14 0 0 0 5.21E+07 2.08E+07 - - - 6.8235 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.22030.22030.3 4.00E-05 13/68 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 -1 17774 22030 3 1911.947011 638.3228 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3960.7 - 5.91E+06 - - - 0.228 - 2.186 0.466 - 149.9 1 2 0 0.0004 18 0 0 0 0.00E+00 0.00E+00 - - - 5.6828 1 230117_WJC_METTL3_WT_vs_EV_F02.22032.22032.2 6.30E-06 15/22 K.FPTYPVPHYSFF.- sp|Q96SI9|STRBP_HUMAN 1 1500.7078 - 17776 22032 2 1500.704455 751.3612 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 6.74 3960.8 - 2.08E+06 - - - -2.221 - 2.245 0.56 - 623.5 1 2 0 -0.0033 12 0 0 0 - - - - - 5.304 1 230117_WJC_METTL3_WT_vs_EV_F02.22041.22041.2 1.10E-09 16/28 K.AVLDSYEYFAVLAAK.E sp|P82664|RT10_HUMAN 1 1658.8556 1.36 17783 22041 2 1658.855161 830.4351 "28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2" 4.37 3961.8 - 2.55E+06 - - - -0.2496 - 3.229 0.669 - 713.9 1 2 0 -0.0004 15 0 0 0 1.01E+07 7.46E+06 - - - 6.8639 1 230117_WJC_METTL3_WT_vs_EV_F02.22042.22042.2 1.52E-07 19/28 K.AVLDSYEYFAVLAAK[136.11].E sp|P82664|RT10_HUMAN 1 1666.8698 -1 17784 22042 2 1666.866042 834.4422 "28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2" 4.37 3961.9 - 2.27E+06 - - - -2.2395 - 3.377 0.658 - 907.6 1 2 0 -0.0037 15 0 0 0 0.00E+00 0.00E+00 - - - 6.8918 0.8554 230117_WJC_METTL3_WT_vs_EV_F02.22043.22043.2 0.0456 18-Sep K.ANINVENAFF.T sp|P61006|RAB8A_HUMAN 1 1137.5455 - 17785 22043 2 1137.544119 569.78 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 4 3962 - 2.21E+06 - - - -1.1912 - 1.655 0.318 - 141.7 1 1 0 -0.0014 10 0 0 0 - - - - - 2.7956 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.22044.22044.3 3.47E-06 17/44 R.FFALPYVDHFLR.L sp|Q9HD33|RM47_HUMAN 1 1523.7925 0.88 17786 22044 3 1523.78981 508.9381 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 6.74 3962.1 - 2.16E+06 - - - -1.7791 - 2.801 0.365 - 304.4 1 2 0 -0.0027 12 0 0 0 9.57E+06 1.09E+07 - - - 5.4636 1 230117_WJC_METTL3_WT_vs_EV_F02.22045.22045.2 3.16E-05 18-Nov K.DWVFLNYTYK[136.11].R "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN" 2 1355.6641 0.08 17787 22045 2 1355.663009 678.8393 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.83 3962.2 - 1.80E+06 - - - -0.8335 - 2.196 0.51 - 487.7 1 2 0 -0.0011 10 0 0 0 6.13E+05 8.14E+06 - - - 5.0032 0.9665 230117_WJC_METTL3_WT_vs_EV_F02.22048.22048.2 0.000202 14-Aug A.AQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 928.5229 3.25 17790 22048 2 928.52384 465.2687 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3962.6 - 942127 - - - 0.9617 - 1.807 0.359 - 184.3 1 1 0 0.0009 8 0 0 0 5.51E+06 1.69E+06 - - - 3.4767 1 230117_WJC_METTL3_WT_vs_EV_F02.22053.22053.2 4.83E-07 20-Dec K.VMVQPINLIFR.Y sp|P62304|RUXE_HUMAN 1 1328.7639 1.37 17793 22053 2 1328.76554 665.3892 Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1 9.72 3963.2 - 4.10E+07 - - - 1.2621 - 2.301 0.557 - 475.6 1 2 0 0.0017 11 0 0 0 1.18E+08 8.65E+07 - - - 5.4089 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22058.22058.2 0.491 16-Nov R.C[160.03]LLAYFLDK.S "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1141.5842 8.6 17798 22058 2 1141.585437 571.7994 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 5.83 3963.5 - 3.13E+06 - - - 1.1116 - 2.225 0.373 - 419.7 1 2 0 0.0013 9 0 0 0 1.84E+07 2.14E+06 - - - 4.1093 1 230117_WJC_METTL3_WT_vs_EV_F02.22060.22060.2 0.000186 20-Nov R.IAFWDDVYGFK.M sp|O60678|ANM3_HUMAN 1 1359.6499 -1 17800 22060 2 1359.649783 680.8322 Protein arginine N-methyltransferase 3 OS=Homo sapiens OX=9606 GN=PRMT3 PE=1 SV=4 4.21 3963.6 - 2.27E+06 - - - -0.1147 - 2.265 0.474 - 386.8 1 2 0 -0.0002 11 0 0 0 0.00E+00 0.00E+00 - - - 4.7536 1 230117_WJC_METTL3_WT_vs_EV_F02.22061.22061.2 1.41E-06 20-Nov R.IAFWDDVYGFK[136.11].M sp|O60678|ANM3_HUMAN 1 1367.6641 -1 17801 22061 2 1367.664579 684.8393 Protein arginine N-methyltransferase 3 OS=Homo sapiens OX=9606 GN=PRMT3 PE=1 SV=4 4.21 3963.6 - 2.07E+06 - - - 0.3217 - 2.313 0.502 - 380.3 1 2 0 0.0004 11 0 0 0 0.00E+00 0.00E+00 - - - 5.0171 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.22062.22062.3 3.95E-06 13/44 R.FFALPYVDHFLR[166.11].L sp|Q9HD33|RM47_HUMAN 1 1533.8008 0.88 17802 22062 3 1533.800679 512.2742 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 6.74 3963.7 - 1.92E+06 - - - -0.073 - 2.271 0.445 - 170.6 1 2 0 -0.0001 12 0 0 0 9.57E+06 1.09E+07 - - - 5.7748 1 230117_WJC_METTL3_WT_vs_EV_F02.22063.22063.3 1.61E-05 16/48 R.C[160.03]LFTLLGHLDYIR.T "sp|P53621|COPA_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ITX2|A0A3B3ITX2_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 6 1619.8494 -1 17803 22063 3 1619.851208 540.9571 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 6.73 3963.8 - 1.75E+06 - - - 1.126 - 2.989 0.508 - 334.1 1 2 0 0.0018 13 0 0 0 0.00E+00 0.00E+00 - - - 7.1719 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.22072.22072.2 0.0997 14-Aug R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 22.11 17812 22072 2 1000.558155 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3964.6 - 944562 - - - -1.1773 - 1.679 0.254 - 196.5 1 2 0 -0.0012 8 0 0 0 1.45E+07 6.56E+05 - - - 2.4795 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22076.22076.2 0.00286 20-Oct K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 114.73 17815 22076 2 1106.546806 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3965 - 1.03E+07 - - - 0.3651 - 2.145 0.471 - 265.7 1 2 0 0.0004 11 0 0 0 2.04E+07 1.78E+05 - - - 4.5842 1 230117_WJC_METTL3_WT_vs_EV_F02.22077.22077.2 3.86E-09 14/22 K.LIC[160.03]C[160.03]DILDVLDK.H "sp|P62258|1433E_HUMAN,tr|K7EIT4|K7EIT4_HUMAN" 2 1475.7364 -1 17816 22077 2 1475.735879 738.8755 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 3.93 3965 - 6.43E+06 - - - -0.3449 - 2.725 0.641 - 648.3 1 2 0 -0.0005 12 0 0 0 0.00E+00 0.00E+00 - - - 6.4129 1 230117_WJC_METTL3_WT_vs_EV_F02.22079.22079.2 7.25E-09 22-Dec K.LIC[160.03]C[160.03]DILDVLDK[136.11].H "sp|P62258|1433E_HUMAN,tr|K7EIT4|K7EIT4_HUMAN" 2 1483.7506 1.59 17818 22079 2 1483.75108 742.8826 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 3.93 3965.1 - 4.40E+06 - - - 0.3316 - 2.562 0.621 - 453.3 1 2 0 0.0005 12 0 0 0 1.53E+07 9.61E+06 - - - 6.1029 1 230117_WJC_METTL3_WT_vs_EV_F02.22080.22080.2 0.00106 13/24 R.ALTLGALTLPLAR[166.11].L sp|Q9BSJ8|ESYT1_HUMAN 1 1318.8212 -1 17819 22080 2 1318.821404 660.4179 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 9.79 3965.2 - 4.16E+06 - - - 0.1607 - 2.362 0.499 - 599.4 1 2 0 0.0002 13 0 0 0 0.00E+00 0.00E+00 - - - 4.9325 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.22081.22081.3 0.000438 Dec-56 R.LGLEFFDQPAVPLAR.A "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1671.8984 1.24 17820 22081 3 1671.900472 558.3068 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 4.37 3965.2 - 3.68E+06 - - - 1.2142 - 1.852 0.416 - 107.2 1 2 0 0.002 15 0 0 0 7.76E+06 6.26E+06 - - - 4.7855 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.22082.22082.3 1.29E-06 16/56 R.LGLEFFDQPAVPLAR[166.11].A "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1681.9067 1.24 17821 22082 3 1681.906946 561.6428 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 4.37 3965.3 - 3.37E+06 - - - 0.1391 - 3.124 0.413 - 298.8 1 2 0 0.0002 15 0 0 0 7.76E+06 6.26E+06 - - - 6.1168 0.9962 230117_WJC_METTL3_WT_vs_EV_F02.22085.22085.2 8.47E-05 16/26 K.VPGLPTPIENMILR[166.11].Y "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1558.8781 1.65 17824 22085 2 1558.872287 780.4463 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3965.5 - 1.84E+06 - - - -3.7001 - 2.265 0.463 - 413.6 1 2 0 -0.0058 14 0 0 0 1.04E+07 6.30E+06 - - - 4.5106 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.22088.22088.2 0.00631 20-Aug K.LVPDLLAIVQR.K "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1235.7602 1.21 17827 22088 2 1235.763162 618.8874 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.84 3965.7 - 1.73E+06 - - - 2.4309 - 1.735 0.427 - 272.9 1 2 0 0.003 11 0 0 0 5.75E+06 4.74E+06 - - - 3.6845 0.9943 230117_WJC_METTL3_WT_vs_EV_F02.22089.22089.2 0.245 26-Oct R.VGVDPLIIPTDYWK.K "sp|Q9NQW7|XPP1_HUMAN,tr|Q5T6H2|Q5T6H2_HUMAN,tr|Q5T6H3|Q5T6H3_HUMAN,tr|Q5T6H7|Q5T6H7_HUMAN" 4 1614.8657 -1 17828 22089 2 1614.863968 808.4401 Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3 4.21 3965.8 - 1.53E+06 - - - -1.1004 - 1.546 0.216 - 88.1 1 2 0 -0.0018 14 0 0 0 0.00E+00 0.00E+00 - - - 1.7291 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22090.22090.2 0.0135 16-Oct K.AGLVELLLR.E "sp|Q13425|SNTB2_HUMAN,tr|A0A140TA73|A0A140TA73_HUMAN" 2 982.6175 -1 17829 22090 2 982.619144 492.316 Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1 6.05 3966 - 1.52E+06 - - - 1.6568 - 2.377 0.349 - 333 1 2 0 0.0016 9 0 0 0 0.00E+00 0.00E+00 - - - 4.1231 1 230117_WJC_METTL3_WT_vs_EV_F02.22091.22091.3 2.64E-10 18/76 R.LGLVPVSEASIIIAVSSAHR.A sp|O96007|MOC2B_HUMAN 1 2018.1524 -1 17830 22091 3 2018.155634 673.7248 Molybdopterin synthase catalytic subunit OS=Homo sapiens OX=9606 GN=MOCS2 PE=1 SV=1 6.75 3966.1 - 1.43E+06 - - - 1.5901 - 3.418 0.524 - 347.3 1 2 0 0.0032 20 0 0 0 0.00E+00 0.00E+00 - - - 7.3629 1 230117_WJC_METTL3_WT_vs_EV_F02.22095.22095.2 1.60E-05 13/28 R.LGLEFFDQPAVPLAR[166.11].A "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1681.9067 1.05 17833 22095 2 1681.906592 841.9606 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 4.37 3966.6 - 1.56E+06 - - - -0.0713 - 2.385 0.532 - 418.3 1 2 0 -0.0001 15 0 0 0 1.95E+07 1.86E+07 - - - 5.1073 1 230117_WJC_METTL3_WT_vs_EV_F02.22098.22098.2 3.99E-06 20-Nov K.TFSFAIPLIEK[136.11].L sp|Q9NR30|DDX21_HUMAN 1 1272.7209 0.97 17836 22098 2 1272.721506 637.3677 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.66 3966.8 - 1.47E+07 - - - 0.4565 - 1.972 0.561 - 279.4 1 2 0 0.0006 11 0 0 0 8.29E+07 8.54E+07 - - - 5.0213 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22099.22099.2 4.30E-05 20-Nov K.TFSFAIPLIEK.L sp|Q9NR30|DDX21_HUMAN 1 1264.7067 0.97 17837 22099 2 1264.707285 633.3606 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.66 3966.9 - 1.34E+07 - - - 0.4428 - 1.792 0.51 - 279.5 1 2 0 0.0006 11 0 0 0 8.29E+07 8.54E+07 - - - 4.3857 0.9989 230117_WJC_METTL3_WT_vs_EV_F02.22100.22100.2 0.0433 16-Jun R.FLILPDMLK[136.11].N sp|P62318|SMD3_HUMAN 1 1096.6446 -1 17838 22100 2 1096.645124 549.3296 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.84 3966.9 - 7.63E+06 - - - 0.4879 - 1.372 0.345 - 99 1 2 0 0.0005 9 0 0 0 0.00E+00 0.00E+00 - - - 2.504 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.22101.22101.2 0.0109 16-Sep R.FLILPDMLK.N sp|P62318|SMD3_HUMAN 1 1088.6304 1.22 17839 22101 2 1088.631046 545.3225 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.84 3967 - 6.65E+06 - - - 0.6035 - 1.744 0.425 - 246 1 2 0 0.0007 9 0 0 0 7.29E+07 5.95E+07 - - - 3.7889 1 230117_WJC_METTL3_WT_vs_EV_F02.22102.22102.2 1.21E-07 16/26 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.31 17840 22102 2 1676.899346 839.4565 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3967 - 6.04E+06 - - - 0.5033 - 3.117 0.576 - 858.9 1 2 0 0.0008 14 0 0 0 6.65E+07 5.07E+07 - - - 6.148 1 230117_WJC_METTL3_WT_vs_EV_F02.22105.22105.2 4.27E-07 19/26 M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 1.31 17843 22105 2 1686.907858 844.4607 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3967.1 - 5.31E+06 - - - 0.6438 - 3.282 0.578 - 1282.5 1 2 0 0.0011 14 0 0 0 6.65E+07 5.07E+07 - - - 6.2921 1 230117_WJC_METTL3_WT_vs_EV_F02.22107.22107.3 4.37E-09 18/52 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.4 17845 22107 3 1676.900243 559.9734 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3967.2 - 2.82E+06 - - - 1.0382 - 3.078 0.52 - 444.7 1 2 0 0.0017 14 0 0 0 2.39E+07 1.71E+07 - - - 7.3248 1 230117_WJC_METTL3_WT_vs_EV_F02.22109.22109.3 2.61E-07 14/52 M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 -1 17847 22109 3 1686.910627 563.3095 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3967.3 - 2.10E+06 - - - 2.2852 - 2.874 0.513 - 267.1 1 2 0 0.0039 14 0 0 0 0.00E+00 0.00E+00 - - - 7.0639 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22113.22113.2 1.05E-05 13/24 R.IASGLGLAWIVGR[166.11].V "sp|O14880|MGST3_HUMAN,tr|Q5VV87|Q5VV87_HUMAN,tr|Q5VV89|Q5VV89_HUMAN" 3 1321.7746 -1 17851 22113 2 1321.776184 661.8946 Microsomal glutathione S-transferase 3 OS=Homo sapiens OX=9606 GN=MGST3 PE=1 SV=1 9.75 3967.8 - 1.08E+06 - - - 1.2165 - 2.803 0.374 - 648.9 1 2 0 0.0016 13 0 0 0 0.00E+00 0.00E+00 - - - 4.4482 1 230117_WJC_METTL3_WT_vs_EV_F02.22116.22116.2 0.000475 22-Dec R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 -1 17853 22116 2 1328.718702 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3968.1 - 4.99E+06 - - - -0.0339 - 2.336 0.496 - 387.9 1 2 0 0 12 0 0 0 0.00E+00 0.00E+00 - - - 4.9368 1 230117_WJC_METTL3_WT_vs_EV_F02.22120.22120.2 0.000536 13/22 R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 -1 17857 22120 2 1301.708184 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3968.3 - 7.64E+06 - - - 0.2581 - 2.751 0.549 - 431.7 1 2 0 0.0003 12 0 0 0 0.00E+00 0.00E+00 - - - 5.7585 1 230117_WJC_METTL3_WT_vs_EV_F02.22122.22122.2 7.50E-07 15/26 K.MQLMELAILNGTYR.D "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1651.8426 -1 17859 22122 2 1651.843094 826.9286 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 5.75 3968.4 - 4.46E+06 - - - 0.3087 - 2.941 0.605 - 703.5 1 2 0 0.0005 14 0 0 0 0.00E+00 0.00E+00 - - - 6.2164 0.9847 230117_WJC_METTL3_WT_vs_EV_F02.22123.22123.2 0.498 12-Jun K.DVLDSVL.- sp|P81605|DCD_HUMAN 1 759.4014 - 17860 22123 2 759.400777 380.708 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.56 3968.4 - 3.90E+06 - - - -0.8665 - 1.173 0.172 - 135.8 1 2 0 -0.0007 7 0 0 0 - - - - - 0.8168 1 230117_WJC_METTL3_WT_vs_EV_F02.22124.22124.3 3.98E-08 15/68 K.LLGTIYTAAEEIEAVGGK.A sp|Q6YN16|HSDL2_HUMAN 1 1833.9724 -1 17861 22124 3 1833.975098 612.3314 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3968.5 - 3.87E+06 - - - 1.4738 - 3.015 0.576 - 348.9 1 2 0 0.0027 18 0 0 0 0.00E+00 0.00E+00 - - - 7.7092 1 230117_WJC_METTL3_WT_vs_EV_F02.22125.22125.2 1.13E-11 18/34 K.LLGTIYTAAEEIEAVGGK.A sp|Q6YN16|HSDL2_HUMAN 1 1833.9724 -1 17862 22125 2 1833.97355 917.9935 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3968.6 - 2.76E+06 - - - 0.6298 - 3.748 0.645 - 1085 1 2 0 0.0012 18 0 0 0 0.00E+00 0.00E+00 - - - 7.0529 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.22126.22126.2 0.0131 20-Oct K.LVLADLLEPVK.T sp|Q9BVJ6|UT14A_HUMAN 1 1208.738 1.6 17863 22126 2 1208.744477 605.3763 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3968.6 - 2.50E+06 - - - 5.337 - 1.991 0.379 - 211.1 1 2 0 0.0065 11 0 0 0 2.87E+07 1.80E+07 - - - 3.7012 0.9934 230117_WJC_METTL3_WT_vs_EV_F02.22130.22130.2 0.547 20-Sep R.DFLTPPLLSVR.F sp|O95782|AP2A1_HUMAN 1 1256.7129 -1 17867 22130 2 1256.714039 629.3637 AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A1 PE=1 SV=3 5.84 3968.9 - 1.78E+06 - - - 0.9278 - 1.181 0.177 - 138.9 1 2 0 0.0012 11 0 0 0 0.00E+00 0.00E+00 - - - 0.798 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.22132.22132.2 0.00823 26-Jul K.VPGLPTPIENMILR.Y "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1548.8698 1.65 17869 22132 2 1548.86974 775.4422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3969.2 - 1.67E+06 - - - -0.0291 - 1.834 0.256 - 152.8 1 2 0 0 14 0 0 0 1.04E+07 6.30E+06 - - - 2.4538 0.9944 230117_WJC_METTL3_WT_vs_EV_F02.22133.22133.2 0.00055 24-Nov R.DPQLVPILIEAAR.N "sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 2 1433.8242 -1 17870 22133 2 1433.833479 717.9194 "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=NSDHL PE=1 SV=2" 4.37 3969.2 - 1.55E+06 - - - 6.461 - 2.174 0.418 - 315.9 1 2 0 0.0093 13 0 0 0 0.00E+00 0.00E+00 - - - 4.1185 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.22134.22134.3 0.0113 Nov-52 K.MQLMELAILNGTYR[166.11].D "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1661.8509 1.07 17871 22134 3 1661.852502 554.9576 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 5.75 3969.3 - 1.45E+06 - - - 0.9917 - 2.161 0.346 - 129.3 1 2 0 0.0016 14 0 0 0 6.61E+06 6.16E+06 - - - 4.4449 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.22140.22140.3 0.0134 Nov-44 K.C[160.03]LVFSLIGLHFK[136.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1440.8043 -1 17876 22140 3 1440.804112 481.2754 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3969.7 - 9.45E+06 - - - -0.1152 - 2.096 0.333 - 162.9 1 2 0 -0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 4.3038 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.22141.22141.3 2.86E-05 16/44 K.C[160.03]LVFSLIGLHFK.L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1432.7901 -1 17877 22141 3 1432.789755 478.604 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3969.8 - 6.99E+06 - - - -0.2254 - 2.495 0.454 - 419.4 1 2 0 -0.0003 12 0 0 0 0.00E+00 0.00E+00 - - - 6.1358 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.22143.22143.2 2.23E-05 20-Nov K.LVLADLLEPVK[136.11].T sp|Q9BVJ6|UT14A_HUMAN 1 1216.7522 1.6 17879 22143 2 1216.753277 609.3834 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3969.9 - 2.87E+06 - - - 0.8638 - 2.071 0.375 - 279.5 1 2 0 0.0011 11 0 0 0 2.87E+07 1.80E+07 - - - 3.7799 1 230117_WJC_METTL3_WT_vs_EV_F02.22148.22148.2 1.18E-06 14/22 K.GDLDLELVLLC[160.03]K[136.11].E "sp|Q12906|ILF3_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 1394.7571 -1 17884 22148 2 1394.759296 698.3858 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.03 3970.3 - 1.76E+06 - - - 1.6082 - 2.844 0.574 - 750.1 1 2 0 0.0022 12 0 0 0 0.00E+00 0.00E+00 - - - 6.03 1 230117_WJC_METTL3_WT_vs_EV_F02.22149.22149.2 4.11E-06 14-Nov R.C[160.03]FLSWLVK.L sp|Q92900|RENT1_HUMAN 1 1051.5525 -1 17885 22149 2 1051.553624 526.7835 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.22 3970.4 - 1.64E+06 - - - 1.0936 - 2.036 0.496 - 505.8 1 2 0 0.0012 8 0 0 0 0.00E+00 0.00E+00 - - - 4.8484 0.9976 230117_WJC_METTL3_WT_vs_EV_F02.22158.22158.2 0.124 20-Nov K.VNLLSVLEAAK[136.11].M sp|Q9BRX8|PXL2A_HUMAN 1 1163.7005 -1 17893 22158 2 1163.702336 582.8575 Peroxiredoxin-like 2A OS=Homo sapiens OX=9606 GN=PRXL2A PE=1 SV=3 5.97 3971.5 - 653764 - - - 1.5571 - 1.206 0.276 - 155.8 1 2 0 0.0018 11 0 0 0 0.00E+00 0.00E+00 - - - 1.5857 0.9913 230117_WJC_METTL3_WT_vs_EV_F02.22159.22159.2 0.766 12-Aug K.NIFLLFK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 893.5375 -1 17894 22159 2 893.53839 447.776 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.75 3971.6 - 2.09E+06 - - - 1.024 - 1.369 0.074 - 280.5 1 2 0 0.0009 7 0 0 0 0.00E+00 0.00E+00 - - - 0.5825 1 230117_WJC_METTL3_WT_vs_EV_F02.22160.22160.2 6.79E-06 18-Oct K.GGFDWNLVFK.W sp|Q10471|GALT2_HUMAN 1 1181.5869 1.33 17895 22160 2 1181.588072 591.8007 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.84 3971.7 - 3.82E+06 - - - 0.9538 - 1.809 0.542 - 213.8 1 2 0 0.0011 10 0 0 0 6.96E+06 5.22E+06 - - - 4.6985 1 230117_WJC_METTL3_WT_vs_EV_F02.22161.22161.2 3.29E-06 14/22 K.GDLDLELVLLC[160.03]K.E "sp|Q12906|ILF3_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 1386.7429 -1 17896 22161 2 1386.744043 694.3787 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.03 3971.7 - 3.61E+06 - - - 0.8581 - 2.834 0.539 - 875.2 1 2 0 0.0012 12 0 0 0 0.00E+00 0.00E+00 - - - 5.7625 1 230117_WJC_METTL3_WT_vs_EV_F02.22163.22163.2 0.000371 15/24 K.IPLKPPPLELLNV.- sp|O15504|NUP42_HUMAN 1 1441.8908 2.11 17898 22163 2 1441.892249 721.9527 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 3971.9 - 1.89E+06 - - - 0.9786 - 2.319 0.514 - 769.4 1 2 0 0.0014 13 0 0 0 7.92E+06 3.75E+06 - - - 4.9958 1 230117_WJC_METTL3_WT_vs_EV_F02.22164.22164.2 0.000599 14/26 K.IVQVALNGLENILR.L "sp|O60684|IMA7_HUMAN,sp|O15131|IMA6_HUMAN,sp|P52294|IMA5_HUMAN" 3 1550.9144 -1 17899 22164 2 1550.918262 776.4645 Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1 6 3972 - 1.73E+06 - - - 2.4727 - 3.123 0.47 - 837.5 1 2 0 0.0038 14 0 0 0 0.00E+00 0.00E+00 - - - 5.369 1 230117_WJC_METTL3_WT_vs_EV_F02.22166.22166.2 0.000405 13/22 K.QFEELTLGEFLK[136.11].L "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1460.7642 -1 17901 22166 2 1460.769469 731.3894 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.25 3972.2 - 1.38E+06 - - - 3.5748 - 2.382 0.478 - 682.4 1 2 0 0.0052 12 0 0 0 0.00E+00 0.00E+00 - - - 4.8536 0.9984 230117_WJC_METTL3_WT_vs_EV_F02.22167.22167.2 0.00334 13/26 K.IVQVALNGLENILR[166.11].L "sp|O60684|IMA7_HUMAN,sp|O15131|IMA6_HUMAN,sp|P52294|IMA5_HUMAN" 3 1560.9227 -1 17902 22167 2 1560.929242 781.4686 Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1 6 3972.4 - 1.15E+06 - - - 4.193 - 2.088 0.37 - 419.6 1 2 0 0.0065 14 0 0 0 0.00E+00 0.00E+00 - - - 3.6192 1 230117_WJC_METTL3_WT_vs_EV_F02.22181.22181.3 3.86E-12 25/80 N.WITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 2344.2539 6.2 17915 22181 3 2344.257288 782.4253 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3974 - 1.10E+07 - - - 1.4324 - 3.836 0.624 - 567 1 1 0 0.0034 21 0 0 0 3.06E+07 4.94E+06 - - - 8.7193 1 230117_WJC_METTL3_WT_vs_EV_F02.22183.22183.2 0.00462 18-Dec K.STLLLLLTGK[136.11].L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1065.6889 -1 17917 22183 2 1065.690307 533.8517 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3974.1 - 5.93E+06 - - - 1.3231 - 2.343 0.456 - 553.2 1 2 0 0.0014 10 0 0 0 0.00E+00 0.00E+00 - - - 4.7852 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22184.22184.2 0.0303 16-Sep R.VNILFDFVK.K sp|P55010|IF5_HUMAN 1 1093.6172 -1 17918 22184 2 1093.619186 547.8159 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.81 3974.1 - 5.74E+06 - - - 1.8325 - 2.085 0.402 - 389.1 1 2 0 0.002 9 0 0 0 0.00E+00 0.00E+00 - - - 4.1353 1 230117_WJC_METTL3_WT_vs_EV_F02.22185.22185.2 2.77E-06 18-Oct K.STLLLLLTGK.L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1057.6747 -1 17919 22185 2 1057.676462 529.8446 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3974.2 - 5.73E+06 - - - 1.6688 - 2.026 0.538 - 336.3 1 2 0 0.0018 10 0 0 0 0.00E+00 0.00E+00 - - - 4.985 0.9968 230117_WJC_METTL3_WT_vs_EV_F02.22188.22188.2 0.21 14-Aug K.GSLLDFLK.E "sp|P07947|YES_HUMAN,sp|P09769|FGR_HUMAN,sp|P07948|LYN_HUMAN,sp|P08631|HCK_HUMAN,sp|P06241|FYN_HUMAN,sp|P12931|SRC_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|J3QRU1|J3QRU1_HUMAN" 9 891.5066 -1 17922 22188 2 891.507362 446.7606 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 3974.4 - 4.97E+06 - - - 0.8895 - 1.466 0.156 - 212.8 1 2 0 0.0008 8 0 0 0 0.00E+00 0.00E+00 - - - 1.3467 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.22190.22190.2 0.0848 16-Sep R.VNILFDFVK[136.11].K sp|P55010|IF5_HUMAN 1 1101.6314 -1 17924 22190 2 1101.6309 551.823 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.81 3974.5 - 4.65E+06 - - - -0.4375 - 1.708 0.277 - 293.5 1 2 0 -0.0005 9 0 0 0 0.00E+00 0.00E+00 - - - 2.6355 1 230117_WJC_METTL3_WT_vs_EV_F02.22193.22193.3 0.0003 16/52 K.FLTLPPVLHLQLMR.F "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1676.98 -1 17927 22193 3 1676.98271 560.0006 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 9.76 3974.7 - 2.95E+06 - - - 1.6136 - 2.972 0.486 - 354.5 1 2 0 0.0027 14 0 0 0 0.00E+00 0.00E+00 - - - 6.8523 1 230117_WJC_METTL3_WT_vs_EV_F02.22195.22195.2 0.000165 14/24 R.LLSLISIALPENK.V "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1409.8494 2.57 17929 22195 2 1409.85239 705.932 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 6 3974.8 - 2.59E+06 - - - 2.1442 - 2.75 0.554 - 627.3 1 2 0 0.003 13 0 0 0 8.20E+06 3.20E+06 - - - 5.7282 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.22196.22196.3 0.000285 15/52 K.FLTLPPVLHLQLMR[166.11].F "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1686.9883 -1 17930 22196 3 1686.992075 563.3367 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 9.76 3974.9 - 2.25E+06 - - - 2.2531 - 2.777 0.48 - 245.6 1 2 0 0.0038 14 0 0 0 0.00E+00 0.00E+00 - - - 6.6048 0.9971 230117_WJC_METTL3_WT_vs_EV_F02.22200.22200.2 0.00402 22-Dec R.LAQNILSYLDLK.S sp|Q9UL15|BAG5_HUMAN 1 1389.7868 3.02 17933 22200 2 1389.793419 695.9007 BAG family molecular chaperone regulator 5 OS=Homo sapiens OX=9606 GN=BAG5 PE=1 SV=1 5.83 3975.3 - 1.72E+06 - - - 4.7863 - 1.666 0.393 - 439.7 1 2 0 0.0067 12 0 0 0 4.59E+06 1.52E+06 - - - 3.2846 0.9947 230117_WJC_METTL3_WT_vs_EV_F02.22202.22202.2 0.0357 14-Jun R.GFGFILFK.D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 927.5218 0.86 17935 22202 2 927.521802 464.7682 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3975.4 - 1.31E+07 - - - -0.0248 - 1.31 0.188 - 111 1 2 0 0 8 0 0 0 5.93E+07 6.92E+07 - - - 1.244 1 230117_WJC_METTL3_WT_vs_EV_F02.22208.22208.2 1.08E-06 18-Oct R.DFVVGALILR[166.11].S sp|Q9NUD5|ZCHC3_HUMAN 1 1111.6629 -1 17941 22208 2 1111.662983 556.8387 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 5.84 3975.7 - 2.61E+06 - - - 0.0747 - 1.996 0.521 - 429.3 1 2 0 0.0001 10 0 0 0 0.00E+00 0.00E+00 - - - 4.8183 1 230117_WJC_METTL3_WT_vs_EV_F02.22210.22210.2 4.19E-05 20-Jul R.YFGELLADLSR.K sp|Q8WVV4|POF1B_HUMAN 1 1282.6558 -1 17943 22210 2 1282.654806 642.3352 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 4.37 3975.8 - 2.09E+06 - - - -0.7375 - 1.635 0.58 - 134.1 1 2 0 -0.0009 11 0 0 0 0.00E+00 0.00E+00 - - - 4.6546 1 230117_WJC_METTL3_WT_vs_EV_F02.22212.22212.2 0.000307 18-Sep R.DFVVGALILR.S sp|Q9NUD5|ZCHC3_HUMAN 1 1101.6546 -1 17945 22212 2 1101.659382 551.8346 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 5.84 3975.9 - 1.91E+06 - - - 4.3135 - 2.015 0.511 - 313.4 1 2 0 0.0048 10 0 0 0 0.00E+00 0.00E+00 - - - 4.7694 1 230117_WJC_METTL3_WT_vs_EV_F02.22217.22217.2 6.04E-06 26-Dec R.GLLEESSFATLFPK.Y sp|Q13601|KRR1_HUMAN 1 1537.8028 1.15 17950 22217 2 1537.79993 769.9087 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3976.3 - 1.37E+06 - - - -1.8735 - 2.356 0.498 - 458.4 1 2 0 -0.0029 14 0 0 0 9.86E+06 8.60E+06 - - - 4.8688 1 230117_WJC_METTL3_WT_vs_EV_F02.22222.22222.2 7.59E-09 14/22 R.LGDPLEAFPVFK[136.11].K "sp|Q86UY6|NAA40_HUMAN,tr|F5H2C9|F5H2C9_HUMAN" 2 1339.7267 1.09 17954 22222 2 1339.72467 670.8706 N-alpha-acetyltransferase 40 OS=Homo sapiens OX=9606 GN=NAA40 PE=1 SV=1 4.37 3976.9 - 2.69E+06 - - - -1.5443 - 2.575 0.507 - 729.5 1 2 0 -0.0021 12 0 0 0 1.17E+07 1.08E+07 - - - 5.2737 1 230117_WJC_METTL3_WT_vs_EV_F02.22223.22223.3 1.48E-06 14/60 K.LPIVNEDDELVAIIAR.T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1778.9778 1.7 17955 22223 3 1778.981244 593.9999 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3976.9 - 5.21E+06 - - - 1.9275 - 2.741 0.55 - 234.8 1 2 0 0.0034 16 0 0 0 1.18E+07 6.95E+06 - - - 7.2582 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.22224.22224.2 0.0067 22-Nov K.IIDEDGLLNLIR.T "sp|P35251|RFC1_HUMAN,tr|H0Y8U4|H0Y8U4_HUMAN" 2 1382.7769 -1 17956 22224 2 1382.78045 692.3957 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 4.03 3977 - 3.26E+06 - - - 2.5456 - 2.132 0.248 - 335.7 1 2 0 0.0035 12 0 0 0 0.00E+00 0.00E+00 - - - 2.8636 1 230117_WJC_METTL3_WT_vs_EV_F02.22225.22225.2 6.60E-05 20-Sep R.LWGLTEMFPER.V sp|Q9NS69|TOM22_HUMAN 1 1377.6751 -1 17957 22225 2 1377.676052 689.8448 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 4.53 3977 - 2.77E+06 - - - 0.6852 - 2.138 0.526 - 271.3 1 2 0 0.0009 11 0 0 0 0.00E+00 0.00E+00 - - - 4.9814 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.22227.22227.2 0.0415 16-Sep K.IAILGFAFK.K sp|O60701|UGDH_HUMAN 1 978.5902 -1 17959 22227 2 978.590937 490.3024 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 8.75 3977.2 - 2.60E+06 - - - 0.7133 - 2.111 0.251 - 194.9 1 2 0 0.0007 9 0 0 0 0.00E+00 0.00E+00 - - - 3.0562 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.22229.22229.2 0.00756 16-Jul K.EVWDYVFFK[136.11].E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PRP1|A0A6I8PRP1_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 1239.6056 -1 17961 22229 2 1239.604875 620.8101 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.37 3977.3 - 2.54E+06 - - - -0.5534 - 1.663 0.408 - 180 1 2 0 -0.0007 9 0 0 0 0.00E+00 0.00E+00 - - - 3.5257 1 230117_WJC_METTL3_WT_vs_EV_F02.22231.22231.2 0.000309 26-Oct R.GLLEESSFATLFPK[136.11].Y sp|Q13601|KRR1_HUMAN 1 1545.817 1.15 17963 22231 2 1545.816908 773.9158 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3977.6 - 1.95E+06 - - - -0.0666 - 2.49 0.523 - 261.6 1 2 0 -0.0001 14 0 0 0 9.86E+06 8.60E+06 - - - 5.1932 0.999 230117_WJC_METTL3_WT_vs_EV_F02.22233.22233.3 0.0165 Sep-44 K.LIQLMEEIMAEK.E "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1446.7462 -1 17965 22233 3 1446.747049 483.256 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.25 3977.8 - 1.56E+06 - - - 0.5702 - 1.616 0.299 - 76.9 1 2 0 0.0008 12 0 0 0 0.00E+00 0.00E+00 - - - 3.2037 0.9992 230117_WJC_METTL3_WT_vs_EV_F02.22235.22235.2 1.65 18-Nov K.NIFAILQSVK[136.11].A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1139.6794 -1 17967 22235 2 1139.682628 570.847 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3978.1 - 1.14E+06 - - - 2.8368 - 2.101 0.299 - 266.5 1 2 0 0.0032 10 0 0 0 0.00E+00 0.00E+00 - - - 3.3207 0.9626 230117_WJC_METTL3_WT_vs_EV_F02.22239.22239.2 0.137 20-Aug R.YIFTMLSSLAR[166.11].L sp|P11388|TOP2A_HUMAN 1 1310.6932 -1 17971 22239 2 1310.700111 656.3539 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 8.75 3978.5 - 849128 - - - 5.2621 - 1.537 0.131 - 152.9 2 2 0 0.0069 11 0 0 0 0.00E+00 0.00E+00 - - - 1.0347 1 230117_WJC_METTL3_WT_vs_EV_F02.22242.22242.2 4.19E-08 16/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 5.12 17973 22242 2 1591.94582 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3978.9 - 3.04E+06 - - - 0.5157 - 2.987 0.584 - 567.9 1 2 0 0.0008 15 0 0 0 8.09E+07 1.58E+07 - - - 6.0445 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22243.22243.3 0.11 13/56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 5.85 17974 22243 3 1591.946233 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3979 - 1.96E+06 - - - 0.7752 - 2.337 0.32 - 198.6 1 2 0 0.0012 15 0 0 0 3.67E+07 6.27E+06 - - - 4.3224 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.22244.22244.2 0.0969 18-Oct R.ILGLLDAYLK[136.11].T sp|P26641|EF1G_HUMAN 1 1125.6889 0.86 17975 22244 2 1125.690771 563.8517 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3979 - 3.88E+07 - - - 1.6648 - 2.129 0.265 - 244.2 1 2 0 0.0019 10 0 0 0 5.69E+07 6.62E+07 - - - 3.107 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.22246.22246.2 0.0176 18-Oct R.ILGLLDAYLK.T sp|P26641|EF1G_HUMAN 1 1117.6747 -1 17977 22246 2 1117.676868 559.8446 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3979.1 - 3.32E+07 - - - 1.9424 - 2.23 0.293 - 231.8 1 2 0 0.0022 10 0 0 0 0.00E+00 0.00E+00 - - - 3.443 1 230117_WJC_METTL3_WT_vs_EV_F02.22247.22247.2 5.60E-10 19/30 K.LPIVNEDDELVAIIAR.T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1778.9778 2.22 17978 22247 2 1778.980953 890.4962 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3979.1 - 4.56E+06 - - - 1.7639 - 3.734 0.67 - 1082.2 1 2 0 0.0031 16 0 0 0 1.45E+07 6.51E+06 - - - 7.2277 1 230117_WJC_METTL3_WT_vs_EV_F02.22249.22249.2 7.96E-05 13/22 R.LGPLLDILADSR.H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1281.7293 1.62 17980 22249 2 1281.732334 641.8719 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3979.2 - 3.44E+06 - - - 2.4046 - 2.583 0.445 - 639.6 1 2 0 0.0031 12 0 0 0 3.65E+07 2.24E+07 - - - 4.8237 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.22250.22250.2 0.000209 22-Dec K.VNFLPEIITLSK.E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1372.7966 -1 17981 22250 2 1372.80125 687.4056 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.97 3979.3 - 3.21E+06 - - - 3.3851 - 2.054 0.446 - 404.2 1 2 0 0.0046 12 0 0 0 0.00E+00 0.00E+00 - - - 4.2276 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22252.22252.2 0.00119 22-Oct K.VNFLPEIITLSK[136.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1380.8108 0.91 17983 22252 2 1380.813189 691.4127 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.97 3979.4 - 2.68E+06 - - - 1.728 - 1.871 0.437 - 256.8 1 2 0 0.0024 12 0 0 0 9.84E+06 1.09E+07 - - - 3.9163 1 230117_WJC_METTL3_WT_vs_EV_F02.22253.22253.2 2.40E-09 17/30 K.LPIVNEDDELVAIIAR[166.11].T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1788.9861 -1 17984 22253 2 1788.98803 895.5003 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3979.5 - 1.88E+06 - - - 1.0872 - 3.59 0.647 - 853.9 1 2 0 0.0019 16 0 0 0 0.00E+00 0.00E+00 - - - 6.9615 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.22254.22254.3 5.36E-06 14/60 K.LPIVNEDDELVAIIAR[166.11].T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1788.9861 1.7 17985 22254 3 1788.988123 597.336 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3979.6 - 1.88E+06 - - - 1.1392 - 2.549 0.471 - 284.3 1 2 0 0.002 16 0 0 0 1.18E+07 6.95E+06 - - - 6.1915 1 230117_WJC_METTL3_WT_vs_EV_F02.22256.22256.2 0.00174 13/24 R.SDFFLEGPFMPPR.M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1538.7228 2.12 17987 22256 2 1538.724613 770.3687 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3979.7 - 1.79E+06 - - - 1.1873 - 2.761 0.532 - 602.4 1 2 0 0.0018 13 0 0 0 1.26E+07 5.97E+06 - - - 5.5763 1 230117_WJC_METTL3_WT_vs_EV_F02.22257.22257.3 7.04E-06 14/56 R.TVFRPPLDIYDVLIR.L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0C4DFX0|A0A0C4DFX0_HUMAN" 2 1816.0247 1.08 17988 22257 3 1816.027202 606.3488 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.63 3979.8 - 1.75E+06 - - - 1.3744 - 2.198 0.537 - 163.5 1 2 0 0.0025 15 0 0 0 8.47E+06 7.81E+06 - - - 6.5813 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.22258.22258.2 0.000104 26-Oct K.LLSDFLDSEVSELR.T sp|Q9BPX3|CND3_HUMAN 1 1621.8199 -1 17989 22258 2 1621.822093 811.9172 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 3.92 3979.9 - 1.43E+06 - - - 1.3417 - 1.8 0.437 - 189.6 1 2 0 0.0022 14 0 0 0 0.00E+00 0.00E+00 - - - 3.743 0.9981 230117_WJC_METTL3_WT_vs_EV_F02.22263.22263.2 0.0118 18-Jul K.GGPGLPLPPL.- sp|Q9H7N4|SFR19_HUMAN 1 916.5382 - 17993 22263 2 916.540443 459.2764 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.52 3980.5 - 1.47E+06 - - - 2.444 - 1.34 0.295 - 165.4 1 2 0 0.0022 10 0 0 0 - - - - - 2.0361 1 230117_WJC_METTL3_WT_vs_EV_F02.22266.22266.2 4.41E-06 15/22 R.LGPLLDILADSR[166.11].H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1291.7375 1.62 17996 22266 2 1291.740407 646.876 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3980.6 - 5.24E+06 - - - 2.2334 - 2.931 0.507 - 967.5 1 2 0 0.0029 12 0 0 0 3.65E+07 2.24E+07 - - - 5.6142 1 230117_WJC_METTL3_WT_vs_EV_F02.22267.22267.2 8.52E-05 24-Nov R.GNSIIMLEALERV.- "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1443.7756 -1 17997 22267 2 1443.777961 722.8951 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3980.7 - 3.43E+06 - - - 1.6699 - 2.563 0.492 - 465.8 1 2 0 0.0024 13 0 0 0 0.00E+00 0.00E+00 - - - 5.0897 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22268.22268.2 1.09 13/22 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 1.02 17998 22268 2 1344.864634 673.4385 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3980.7 - 2.96E+06 - - - 1.6277 - 2.395 0.411 - 592.6 1 2 0 0.0022 12 0 0 0 1.73E+08 1.69E+08 - - - 4.374 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22269.22269.2 0.0178 13/22 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 1.02 17999 22269 2 1336.849716 669.4314 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3980.8 - 2.72E+06 - - - 1.1003 - 2.454 0.352 - 579.7 1 2 0 0.0015 12 0 0 0 1.73E+08 1.69E+08 - - - 4.0025 1 230117_WJC_METTL3_WT_vs_EV_F02.22270.22270.2 2.71E-06 24-Nov R.GNSIIMLEALER[166.11]V.- "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1453.7838 -1 18000 22270 2 1453.787378 727.8992 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3980.9 - 2.09E+06 - - - 2.4474 - 2.533 0.525 - 463.9 1 2 0 0.0036 13 0 0 0 0.00E+00 0.00E+00 - - - 5.3029 0.9742 230117_WJC_METTL3_WT_vs_EV_F02.22272.22272.2 1.87 20-Aug R.LLDMDGIIVEK.Q sp|Q14152|EIF3A_HUMAN 1 1244.6686 -1 18002 22272 2 1244.666376 623.3416 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.03 3981 - 1.81E+06 - - - -1.8069 - 1.462 0.108 - 154.3 1 2 0 -0.0022 11 0 0 0 0.00E+00 0.00E+00 - - - 0.8654 1 230117_WJC_METTL3_WT_vs_EV_F02.22276.22276.2 6.13E-10 18/30 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 -1 18006 22276 2 1751.86777 876.9399 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3981.4 - 1.09E+06 - - - 1.4938 - 3.734 0.66 - 894.4 1 2 0 0.0026 16 0 0 0 0.00E+00 0.00E+00 - - - 7.154 1 230117_WJC_METTL3_WT_vs_EV_F02.22277.22277.2 0.0211 24-Dec R.SDFFLEGPFMPPR[166.11].M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1548.7311 2.12 18007 22277 2 1548.734301 775.3728 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3981.5 - 925936 - - - 2.0953 - 2.933 0.549 - 408 1 2 0 0.0032 13 0 0 0 1.26E+07 5.97E+06 - - - 5.8565 1 230117_WJC_METTL3_WT_vs_EV_F02.22279.22279.2 0.000118 16/28 R.SILNADVAELLVVEK.D sp|Q8WVM0|TFB1M_HUMAN 1 1611.9083 1.9 18009 22279 2 1611.912883 806.9614 "Dimethyladenosine transferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=TFB1M PE=1 SV=1" 4.14 3981.7 - 883787 - - - 2.8196 - 2.963 0.434 - 675.7 1 2 0 0.0045 15 0 0 0 3.66E+06 1.92E+06 - - - 4.9156 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.22281.22281.2 0.00031 16-Sep R.MDLFSALIK.G "sp|Q9C0C9|UBE2O_HUMAN,tr|K7ES11|K7ES11_HUMAN" 2 1036.5627 2.58 18011 22281 2 1036.565709 519.2886 (E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3 5.59 3982 - 839077 - - - 2.899 - 1.843 0.38 - 257.3 1 2 0 0.003 9 0 0 0 3.90E+06 1.51E+06 - - - 3.6155 0.9599 230117_WJC_METTL3_WT_vs_EV_F02.22282.22282.3 0.106 Nov-60 R.IPAEVLILNSIVLPHK.E "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 2 1755.0658 2.19 18012 22282 3 1755.065727 586.0292 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 6.75 3982.1 - 737844 - - - -0.0655 - 1.308 0.144 - 110.1 1 2 0 -0.0001 16 0 0 0 5.33E+06 2.43E+06 - - - 0.8344 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.22284.22284.2 0.128 18-Oct K.NIFAILQSVK.A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1131.6652 1.74 18013 22284 2 1131.667121 566.8399 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3982.3 - 1.05E+06 - - - 1.7019 - 2.038 0.338 - 236 1 2 0 0.0019 10 0 0 0 2.69E+07 1.54E+07 - - - 3.5242 1 230117_WJC_METTL3_WT_vs_EV_F02.22285.22285.2 4.21E-06 13/28 R.SILNADVAELLVVEK[136.11].D sp|Q8WVM0|TFB1M_HUMAN 1 1619.9225 -1 18014 22285 2 1619.925368 810.9685 "Dimethyladenosine transferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=TFB1M PE=1 SV=1" 4.14 3982.4 - 252807 - - - 1.747 - 2.395 0.515 - 372.2 1 2 0 0.0028 15 0 0 0 0.00E+00 0.00E+00 - - - 4.9912 0.9702 230117_WJC_METTL3_WT_vs_EV_F02.22286.22286.2 0.00332 14-Jul R.EC[160.03]LNLWGY.E sp|Q86U44|MTA70_HUMAN 1 1053.459 - 18015 22286 2 1053.460156 527.7368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3982.5 - 3.34E+06 - - - 1.1287 - 1.554 0.442 - 197.9 1 1 0 0.0012 8 0 0 0 - - - - - 3.6348 1 230117_WJC_METTL3_WT_vs_EV_F02.22287.22287.3 1.31E-07 15/60 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 2.79 18016 22287 3 1751.867581 584.9623 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3982.5 - 2.59E+06 - - - 1.386 - 3.063 0.541 - 377.6 1 2 0 0.0024 16 0 0 0 1.96E+07 7.05E+06 - - - 7.4432 1 230117_WJC_METTL3_WT_vs_EV_F02.22288.22288.2 0.000249 13/18 K.LASDLLEWIR.R "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|G3V2W4|G3V2W4_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 14 1214.6659 1.22 18017 22288 2 1214.667433 608.3402 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.37 3982.6 - 2.40E+06 - - - 1.2431 - 2.601 0.442 - 697.9 1 2 0 0.0015 10 0 0 0 1.04E+07 8.48E+06 - - - 4.9733 0.9975 230117_WJC_METTL3_WT_vs_EV_F02.22289.22289.3 1.37E-07 18/44 K.LREC[160.03]LPLIIFLR.N sp|P62701|RS4X_HUMAN 1 1541.9116 0.93 18018 22289 3 1541.913702 514.9778 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3982.7 - 2.04E+06 - - - 1.3697 - 3.396 0.474 - 670.9 1 2 1 0.0021 12 0 0 0 6.27E+07 6.75E+07 - - - 7.2129 1 230117_WJC_METTL3_WT_vs_EV_F02.22290.22290.2 1.38E-10 17/30 K.VGEVTYVELLMDAEGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1759.8794 -1 18019 22290 2 1759.880282 880.947 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3982.8 - 1.64E+06 - - - 0.5279 - 3.338 0.642 - 751.4 1 2 0 0.0009 16 0 0 0 0.00E+00 0.00E+00 - - - 6.746 0.9356 230117_WJC_METTL3_WT_vs_EV_F02.22293.22293.2 0.00898 22-Aug R.ISLGLPVGAVIN.C "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1151.6914 - 18022 22293 2 1151.693528 576.853 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.52 3983 - 1.26E+06 - - - 1.839 - 1.682 0.316 - 99.4 2 1 0 0.0021 12 0 0 0 - - - - - 2.608 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.22294.22294.3 2.82E-06 13/44 R.LFVWEILHSTIR[166.11].K "sp|Q09161|NCBP1_HUMAN,tr|X6R941|X6R941_HUMAN" 2 1522.8536 1.19 18023 22294 3 1522.857218 508.6251 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 6.75 3983.1 - 1.19E+06 - - - 2.4054 - 2.375 0.357 - 224.2 1 2 0 0.0037 12 0 0 0 4.21E+06 3.54E+06 - - - 4.9168 1 230117_WJC_METTL3_WT_vs_EV_F02.22295.22295.3 3.97E-07 16/44 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 1 18024 22295 3 1344.864199 449.2948 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3983.2 - 1.15E+06 - - - 1.3042 - 2.699 0.514 - 347 1 2 0 0.0018 12 0 0 0 1.48E+07 1.48E+07 - - - 7.0222 0.9991 230117_WJC_METTL3_WT_vs_EV_F02.22296.22296.2 0.022 20-Nov K.LGELPSWILMR[166.11].D "sp|P56134|ATPK_HUMAN,tr|G3V325|G3V325_HUMAN,tr|C9JU26|C9JU26_HUMAN,tr|C9JJT5|C9JJT5_HUMAN" 4 1323.7248 -1 18025 22296 2 1323.729363 662.8697 "ATP synthase subunit f, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MF PE=1 SV=3" 6 3983.3 - 1.02E+06 - - - 3.4101 - 2.125 0.361 - 320.5 1 2 0 0.0045 11 0 0 0 0.00E+00 0.00E+00 - - - 3.7451 1 230117_WJC_METTL3_WT_vs_EV_F02.22297.22297.3 1.51E-08 14/60 K.VGEVTYVELLMDAEGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1759.8794 2.79 18026 22297 3 1759.882205 587.6337 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3983.4 - 879912 - - - 1.6206 - 2.848 0.573 - 280.3 1 2 0 0.0029 16 0 0 0 1.96E+07 7.05E+06 - - - 7.6131 0.9783 230117_WJC_METTL3_WT_vs_EV_F02.22303.22303.3 0.0413 Jul-44 R.LGPLLDILADSR.H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1281.7293 2.12 18032 22303 3 1281.730633 428.2504 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3984.1 - 430987 - - - 1.0775 - 1.401 0.138 - 52.6 1 2 0 0.0014 12 0 0 0 1.33E+06 6.28E+05 - - - 1.0128 1 230117_WJC_METTL3_WT_vs_EV_F02.22307.22307.2 1.05E-06 19/28 K.LGLLGLANSLAIEGR.K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1495.8722 -1 18035 22307 2 1495.874207 748.9434 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3984.5 - 4.13E+06 - - - 1.323 - 3.791 0.55 - 1332.8 1 2 0 0.002 15 0 0 0 0.00E+00 0.00E+00 - - - 6.379 1 230117_WJC_METTL3_WT_vs_EV_F02.22308.22308.3 0.000949 15/44 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 0.99 18036 22308 3 1336.849871 446.6234 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3984.6 - 2.60E+06 - - - 1.2163 - 2.818 0.528 - 334.3 1 2 0 0.0016 12 0 0 0 1.47E+07 1.48E+07 - - - 7.2979 1 230117_WJC_METTL3_WT_vs_EV_F02.22309.22309.2 2.93E-05 22-Nov K.SVEELLEAELLK[136.11].V "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 1379.7639 -1 18037 22309 2 1379.766928 690.8892 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.09 3984.7 - 2.30E+06 - - - 2.1852 - 2.555 0.472 - 302.6 1 2 0 0.003 12 0 0 0 0.00E+00 0.00E+00 - - - 4.9944 1 230117_WJC_METTL3_WT_vs_EV_F02.22310.22310.2 0.000133 22-Nov R.YLDFSSIITEVR.A sp|Q8N1N4|K2C78_HUMAN 1 1441.7453 -1 18038 22310 2 1441.747348 721.8799 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.37 3984.7 - 2.25E+06 - - - 1.4233 - 2.357 0.545 - 305.5 1 2 0 0.0021 12 0 0 0 0.00E+00 0.00E+00 - - - 5.3217 1 230117_WJC_METTL3_WT_vs_EV_F02.22311.22311.2 2.38E-05 20-Dec K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 -1 18039 22311 2 1315.788677 658.9005 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3984.8 - 1.85E+06 - - - 1.751 - 2.21 0.559 - 475.7 1 2 0 0.0023 11 0 0 0 0.00E+00 0.00E+00 - - - 5.3143 1 230117_WJC_METTL3_WT_vs_EV_F02.22312.22312.2 1.16E-05 16/28 K.LGLLGLANSLAIEGR[166.11].K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1505.8805 -1 18040 22312 2 1505.883838 753.9475 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3984.9 - 1.82E+06 - - - 2.218 - 3.296 0.591 - 995.5 1 2 0 0.0033 15 0 0 0 0.00E+00 0.00E+00 - - - 6.3374 1 230117_WJC_METTL3_WT_vs_EV_F02.22313.22313.3 1.45E-05 20/56 K.LGLLGLANSLAIEGR.K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1495.8722 -1 18041 22313 3 1495.875086 499.6314 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3984.9 - 1.74E+06 - - - 1.9106 - 3.418 0.52 - 582.4 1 2 0 0.0029 15 0 0 0 0.00E+00 0.00E+00 - - - 7.5438 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22314.22314.2 1.87E-05 18-Oct K.VLVYELLLGK.G sp|Q96P11|NSUN5_HUMAN 1 1145.706 -1 18042 22314 2 1145.70823 573.8603 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 5.97 3985 - 1.70E+06 - - - 1.949 - 2.004 0.448 - 282 1 2 0 0.0022 10 0 0 0 0.00E+00 0.00E+00 - - - 4.2896 1 230117_WJC_METTL3_WT_vs_EV_F02.22318.22318.2 3.86E-05 22-Nov R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 15.47 18046 22318 2 1603.765637 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3985.4 - 758281 - - - 1.0581 - 2.039 0.503 - 333.1 1 2 0 0.0017 12 0 0 0 5.07E+06 3.27E+05 - - - 4.6302 1 230117_WJC_METTL3_WT_vs_EV_F02.22319.22319.2 4.35E-06 26-Dec R.ALVENC[160.03]LVPDLWIR.Y "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 1696.8971 -1 18047 22319 2 1696.900425 849.4558 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.37 3985.6 - 717564 - - - 1.9813 - 2.445 0.526 - 435.6 1 2 0 0.0034 14 0 0 0 0.00E+00 0.00E+00 - - - 5.1685 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.22320.22320.3 0.00438 Oct-44 K.SVEELLEAELLK[136.11].V "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 1379.7639 -1 18048 22320 3 1379.765071 460.9286 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.09 3985.7 - 652569 - - - 0.8393 - 1.886 0.338 - 197.6 1 2 0 0.0012 12 0 0 0 0.00E+00 0.00E+00 - - - 4.0667 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22324.22324.2 3.43E-05 28-Nov R.YLPDTLLLEEC[160.03]GLLR[166.11].K "sp|P21964|COMT_HUMAN,tr|E7EMS6|E7EMS6_HUMAN" 2 1813.9523 -1 18052 22324 2 1813.955772 907.9834 Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT PE=1 SV=2 4.14 3986.2 - 546669 - - - 1.8909 - 2.247 0.436 - 278.7 1 2 0 0.0034 15 0 0 0 0.00E+00 0.00E+00 - - - 4.2506 0.9959 230117_WJC_METTL3_WT_vs_EV_F02.22327.22327.3 0.135 Sep-44 K.SVEELLEAELLK.V "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 1371.7497 -1 18054 22327 3 1371.751381 458.2572 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.09 3986.6 - 845477 - - - 1.216 - 1.504 0.219 - 109.3 1 2 0 0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 2.1124 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22330.22330.2 0.000866 18-Oct K.LNMILVQILK.Q "sp|O14980|XPO1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 1183.7363 -1 18057 22330 2 1183.737356 592.8754 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3986.7 - 6.47E+06 - - - 0.9335 - 2.245 0.369 - 382 1 2 0 0.0011 10 0 0 0 0.00E+00 0.00E+00 - - - 4.0234 1 230117_WJC_METTL3_WT_vs_EV_F02.22331.22331.2 1.20E-07 19/28 R.LPFLSSSNLSLDVLR.G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1659.9196 -1 18058 22331 2 1659.920201 830.9671 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3986.7 - 6.09E+06 - - - 0.3789 - 3.605 0.602 - 1275.4 1 2 0 0.0006 15 0 0 0 0.00E+00 0.00E+00 - - - 6.6398 1 230117_WJC_METTL3_WT_vs_EV_F02.22332.22332.2 0.00283 18-Dec K.LNMILVQILK[136.11].Q "sp|O14980|XPO1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 1191.7505 -1 18059 22332 2 1191.751612 596.8825 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3986.8 - 4.47E+06 - - - 0.9742 - 2.478 0.458 - 482.2 1 2 0 0.0012 10 0 0 0 0.00E+00 0.00E+00 - - - 4.9564 1 230117_WJC_METTL3_WT_vs_EV_F02.22334.22334.2 0.00144 22-Nov R.NLQNLLILTAIK[136.11].A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1360.8533 0.99 18061 22334 2 1360.851578 681.4339 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3986.9 - 3.54E+06 - - - -1.2926 - 2.074 0.505 - 344.8 1 2 0 -0.0018 12 0 0 0 4.22E+07 4.26E+07 - - - 4.6898 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22336.22336.2 9.25E-06 20-Oct K.EYPFILDAFQR.E sp|P42285|MTREX_HUMAN 1 1397.698 1.1 18063 22336 2 1397.698354 699.8563 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 3987 - 2.92E+06 - - - 0.2876 - 2.049 0.486 - 414.8 1 2 0 0.0004 11 0 0 0 8.44E+06 7.68E+06 - - - 4.5711 1 230117_WJC_METTL3_WT_vs_EV_F02.22337.22337.2 2.72E-06 28-Dec K.LTILQSLGDPLYYGK.L "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 1679.9134 1.5 18064 22337 2 1679.916265 840.964 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.83 3987.1 - 2.88E+06 - - - 1.6912 - 2.496 0.532 - 403.9 1 2 0 0.0028 15 0 0 0 8.59E+06 5.74E+06 - - - 5.2183 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.22338.22338.3 0.00426 Nov-40 K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 -1 18065 22338 3 1315.787164 439.6027 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3987.2 - 2.69E+06 - - - 0.6012 - 2.236 0.401 - 219.2 1 2 0 0.0008 11 0 0 0 0.00E+00 0.00E+00 - - - 5.2965 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.22339.22339.2 0.000708 20-Oct K.EYPFILDAFQR[166.11].E sp|P42285|MTREX_HUMAN 1 1407.7062 1.1 18066 22339 2 1407.706639 704.8604 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 3987.2 - 2.32E+06 - - - 0.2962 - 1.948 0.471 - 449.8 1 2 0 0.0004 11 0 0 0 8.44E+06 7.68E+06 - - - 4.3235 1 230117_WJC_METTL3_WT_vs_EV_F02.22340.22340.2 3.86E-05 26-Oct K.ELAEEGVLEEAEFY.N sp|Q14681|KCTD2_HUMAN 1 1626.7301 - 18067 22340 2 1626.729887 814.3723 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 3.46 3987.3 - 2.15E+06 - - - -0.1303 - 1.981 0.521 - 163 1 1 0 -0.0002 14 0 0 0 - - - - - 4.6045 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.22341.22341.3 1.54E-07 14/76 K.MLLDPMGGIVMTNDGNAILR[166.11].E "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 2140.0718 -1 18068 22341 3 2140.074904 714.3646 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.21 3987.4 - 1.67E+06 - - - 1.4401 - 2.514 0.473 - 173.3 1 2 0 0.0031 20 0 0 0 0.00E+00 0.00E+00 - - - 6.0491 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.22342.22342.3 0.000319 16/72 R.YAIC[160.03]SALAASALPALVMSK[136.11].G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 1944.0304 -1 18069 22342 3 1944.033429 649.0174 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.2 3987.4 - 1.55E+06 - - - 1.5627 - 2.282 0.396 - 252.1 1 2 0 0.003 19 0 0 0 0.00E+00 0.00E+00 - - - 4.9812 1 230117_WJC_METTL3_WT_vs_EV_F02.22344.22344.2 1.34E-08 16/28 K.GVFVQSVLPYFVATK.L "sp|Q53GQ0|DHB12_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN" 2 1653.913 0.47 18071 22344 2 1653.917817 827.9638 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 8.59 3987.7 - 1.36E+06 - - - 2.8943 - 2.758 0.577 - 618.3 1 2 0 0.0048 15 0 0 0 8.08E+06 1.73E+07 - - - 5.7954 1 230117_WJC_METTL3_WT_vs_EV_F02.22345.22345.2 5.77E-10 19/24 K.APDEETLIALLAH.A "sp|Q9Y3E5|PTH2_HUMAN,tr|J3KQ48|J3KQ48_HUMAN" 2 1391.7296 - 18072 22345 2 1391.730754 696.8721 "Peptidyl-tRNA hydrolase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PTRH2 PE=1 SV=1" 4.13 3987.8 - 1.30E+06 - - - 0.7961 - 3.814 0.658 - 1136.5 1 1 0 0.0011 13 0 0 0 - - - - - 7.3364 1 230117_WJC_METTL3_WT_vs_EV_F02.22349.22349.2 1.41E-07 15/22 K.TSDLIVLGLPWK[136.11].T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1348.7846 -1 18075 22349 2 1348.786123 675.3996 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3988.2 - 1.77E+07 - - - 1.1381 - 3.007 0.615 - 823.6 1 2 0 0.0015 12 0 0 0 0.00E+00 0.00E+00 - - - 6.4797 1 230117_WJC_METTL3_WT_vs_EV_F02.22350.22350.2 8.03E-06 22-Dec R.NLQNLLILTAIK.A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1352.8391 1 18076 22350 2 1352.841134 677.4268 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3988.2 - 1.24E+07 - - - 1.4762 - 2.496 0.594 - 436 1 2 0 0.002 12 0 0 0 4.22E+07 4.24E+07 - - - 5.8344 1 230117_WJC_METTL3_WT_vs_EV_F02.22351.22351.2 2.60E-07 16/28 R.LPFLSSSNLSLDVLR[166.11].G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1669.9278 -1 18077 22351 2 1669.929047 835.9712 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3988.3 - 1.00E+07 - - - 0.7216 - 3.201 0.621 - 906.4 1 2 0 0.0012 15 0 0 0 0.00E+00 0.00E+00 - - - 6.4878 1 230117_WJC_METTL3_WT_vs_EV_F02.22354.22354.2 1.13E-05 22-Dec K.LGTLSALDILIK.N "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1255.7751 -1 18080 22354 2 1255.775891 628.8948 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 5.84 3988.4 - 5.25E+06 - - - 0.5988 - 2.702 0.462 - 692.1 1 2 0 0.0008 12 0 0 0 0.00E+00 0.00E+00 - - - 5.0685 0.9493 230117_WJC_METTL3_WT_vs_EV_F02.22355.22355.2 0.0027 18-Jul E.QEEDISSLIR.S sp|P78527|PRKDC_HUMAN 1 1188.5986 6.33 18081 22355 2 1188.599676 595.3066 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.14 3988.5 - 4.76E+06 - - - 0.8783 - 1.55 0.356 - 152.5 1 1 0 0.001 10 0 0 0 3.36E+07 5.31E+06 - - - 2.8934 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22358.22358.3 0.000409 Oct-56 R.LPFLSSSNLSLDVLR.G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1659.9196 -1 18084 22358 3 1659.921822 554.3138 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3988.6 - 3.44E+06 - - - 1.3555 - 1.646 0.384 - 108.2 1 2 0 0.0022 15 0 0 0 0.00E+00 0.00E+00 - - - 4.121 1 230117_WJC_METTL3_WT_vs_EV_F02.22359.22359.2 2.62E-07 14/24 K.GIVSEEAYILFVR.K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1494.8082 1.29 18085 22359 2 1494.808254 748.4114 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.53 3988.7 - 2.84E+06 - - - 0.0161 - 3.026 0.48 - 1015.9 1 2 0 0 13 0 0 0 1.02E+07 7.91E+06 - - - 5.428 1 230117_WJC_METTL3_WT_vs_EV_F02.22361.22361.2 3.75E-07 17/32 K.LFEMVLGPAAYNVPLPK.K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1858.0063 2.07 18087 22361 2 1858.012781 930.0104 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6 3988.8 - 2.39E+06 - - - 3.5 - 3.486 0.609 - 931.1 1 2 0 0.0065 17 0 0 0 6.43E+06 3.10E+06 - - - 6.6072 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.22363.22363.3 0.00132 13/48 K.GIVSEEAYILFVR.K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1494.8082 2.04 18089 22363 3 1494.808551 499.2767 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.53 3988.9 - 1.85E+06 - - - 0.2147 - 1.961 0.524 - 63.1 1 2 0 0.0003 13 0 0 0 5.51E+06 2.70E+06 - - - 6.2079 1 230117_WJC_METTL3_WT_vs_EV_F02.22364.22364.2 5.21E-06 15/26 R.ISLPLPNFSSLNLR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1569.8879 1.84 18090 22364 2 1569.893441 785.9512 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3989.1 - 1.56E+06 - - - 3.5436 - 2.52 0.58 - 621.4 1 2 0 0.0056 14 0 0 0 6.01E+06 3.26E+06 - - - 5.6425 1 230117_WJC_METTL3_WT_vs_EV_F02.22365.22365.2 6.51E-05 24-Nov K.GIVSEEAYILFVR[166.11].K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1504.8165 1.63 18091 22365 2 1504.818751 753.4155 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.53 3989.1 - 1.45E+06 - - - 1.4959 - 2.496 0.519 - 407.2 1 2 0 0.0022 13 0 0 0 1.02E+07 6.29E+06 - - - 5.2212 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.22369.22369.3 2.21E-05 Nov-44 R.NLQNLLILTAIK.A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1352.8391 1.03 18094 22369 3 1352.838112 451.9537 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3989.6 - 1.33E+06 - - - -0.7577 - 2.27 0.407 - 270.9 1 2 0 -0.001 12 0 0 0 4.19E+06 4.05E+06 - - - 5.3497 1 230117_WJC_METTL3_WT_vs_EV_F02.22371.22371.2 1.42E-05 15/26 R.VISGVLQLGNIVFK[136.11].K sp|P35579|MYH9_HUMAN 1 1493.9061 0.86 18096 22371 2 1493.908097 747.9603 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.72 3989.7 - 1.60E+06 - - - 1.3361 - 2.868 0.561 - 644.4 1 2 0 0.002 14 0 0 0 1.57E+07 1.82E+07 - - - 5.8279 1 230117_WJC_METTL3_WT_vs_EV_F02.22372.22372.3 4.41E-05 22/72 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 18097 22372 3 1911.182757 638.0676 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3989.8 - 1.53E+06 - - - 0.9863 - 3.65 0.571 - 655.1 1 2 0 0.0019 19 0 0 0 0.00E+00 0.00E+00 - - - 8.0865 1 230117_WJC_METTL3_WT_vs_EV_F02.22374.22374.2 1.40E-06 15/24 R.DPTYFGPVLNYLR[166.11].H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1563.7961 0.78 18099 22374 2 1563.799087 782.9053 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3990 - 1.41E+06 - - - 1.9107 - 2.575 0.597 - 812.5 1 2 0 0.003 13 0 0 0 7.76E+06 9.96E+06 - - - 5.8771 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.22378.22378.2 0.00144 13/22 K.NVLITDFFGSVR.K "sp|Q92643|GPI8_HUMAN,tr|B1AK81|B1AK81_HUMAN,tr|A6NEM5|A6NEM5_HUMAN" 3 1366.7245 1.18 18103 22378 2 1366.729193 684.3695 GPI-anchor transamidase OS=Homo sapiens OX=9606 GN=PIGK PE=1 SV=2 5.84 3990.3 - 1.25E+06 - - - 3.433 - 2.236 0.402 - 507.5 1 2 0 0.0047 12 0 0 0 3.90E+06 3.31E+06 - - - 4.126 1 230117_WJC_METTL3_WT_vs_EV_F02.22379.22379.2 1.40E-06 15/24 K.GNLEVLLFTIQSK.L "sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 5 1460.8239 1.34 18104 22379 2 1460.824885 731.4192 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6 3990.4 - 1.25E+06 - - - 0.6873 - 2.84 0.518 - 874 1 2 0 0.001 13 0 0 0 5.15E+06 3.84E+06 - - - 5.5456 1 230117_WJC_METTL3_WT_vs_EV_F02.22380.22380.2 0.00158 16/36 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 18105 22380 2 1911.180098 956.5977 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3990.6 - 1.01E+06 - - - -0.405 - 2.889 0.538 - 595.4 1 2 0 -0.0008 19 0 0 0 0.00E+00 0.00E+00 - - - 5.6227 0.9677 230117_WJC_METTL3_WT_vs_EV_F02.22381.22381.3 0.429 Jul-44 K.TSDLIVLGLPWK.T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1340.7704 -1 18106 22381 3 1340.773632 447.9307 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3990.7 - 803138 - - - 2.4195 - 1.19 0.167 - 68.5 1 2 0 0.0032 12 0 0 0 0.00E+00 0.00E+00 - - - 0.8832 0.9929 230117_WJC_METTL3_WT_vs_EV_F02.22383.22383.3 0.0746 Nov-48 K.GNLEVLLFTIQSK[136.11].L "sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 5 1468.8381 1.04 18108 22383 3 1468.83848 490.62 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6 3990.9 - 768548 - - - 0.2716 - 1.679 0.172 - 102 1 2 0 0.0004 13 0 0 0 2.33E+06 2.24E+06 - - - 1.8625 1 230117_WJC_METTL3_WT_vs_EV_F02.22385.22385.2 1.46E-07 Sep-32 K.LFEMVLGPAAYNVPLPK[136.11].K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1866.0205 -1 18110 22385 2 1866.021398 934.0175 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6 3991.1 - 643108 - - - 0.493 - 2.219 0.568 - 232.8 1 2 0 0.0009 17 0 0 0 0.00E+00 0.00E+00 - - - 5.1956 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.22387.22387.2 0.000229 26-Nov R.ISLPLPNFSSLNLR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1579.8961 1.68 18112 22387 2 1579.897004 790.9554 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3991.4 - 571342 - - - 0.5418 - 1.847 0.428 - 277.8 1 2 0 0.0009 14 0 0 0 9.81E+06 5.86E+06 - - - 3.7416 1 230117_WJC_METTL3_WT_vs_EV_F02.22390.22390.2 1.42E-06 30-Nov R.MTLADDVTLDDLIMAK[136.11].D sp|P62191|PRS4_HUMAN 1 1771.8827 -1 18114 22390 2 1771.880191 886.9486 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 3.77 3991.9 - 210957 - - - -1.4296 - 2.272 0.573 - 237.7 1 2 0 -0.0025 16 0 0 0 0.00E+00 0.00E+00 - - - 5.29 0.9661 230117_WJC_METTL3_WT_vs_EV_F02.22391.22391.2 0.000201 18-Aug K.VEDLTFTSPF.C "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1154.5496 - 18115 22391 2 1154.551888 578.2821 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 3.67 3991.9 - 1.05E+07 - - - 2.0198 - 1.473 0.469 - 167.2 1 1 0 0.0023 10 0 0 0 - - - - - 3.5854 1 230117_WJC_METTL3_WT_vs_EV_F02.22392.22392.3 1.06E-07 15/64 R.AFLQGGQEATDIALLLR.D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1814.989 -1 18116 22392 3 1814.992473 606.0036 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3992 - 5.69E+06 - - - 1.8871 - 3.427 0.56 - 255.2 1 2 0 0.0034 17 0 0 0 0.00E+00 0.00E+00 - - - 7.8941 1 230117_WJC_METTL3_WT_vs_EV_F02.22395.22395.2 1.16E-06 14/20 R.VLDLVEVLVTK[136.11].Q "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1234.7628 0.73 18119 22395 2 1234.765172 618.3887 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.37 3992.1 - 2.98E+06 - - - 1.9291 - 2.868 0.6 - 618.7 1 2 0 0.0024 11 0 0 0 5.05E+06 6.91E+06 - - - 6.3221 0.9153 230117_WJC_METTL3_WT_vs_EV_F02.22396.22396.2 2.92 18-Apr R.C[160.03]FSTTLLYC[160.03]R.K sp|P60893|GPR85_HUMAN 1 1319.6002 -1 18120 22396 2 1319.598654 660.8074 Probable G-protein coupled receptor 85 OS=Homo sapiens OX=9606 GN=GPR85 PE=1 SV=1 8.06 3992.2 - 2.76E+06 - - - -1.1935 - 1.067 0.09 - 43.6 2 2 0 -0.0016 10 0 0 0 0.00E+00 0.00E+00 - - - -0.2482 0.9985 230117_WJC_METTL3_WT_vs_EV_F02.22399.22399.2 0.0151 13/20 R.VLDLVEVLVTK.Q "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1226.7486 -1 18123 22399 2 1226.751373 614.3816 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.37 3992.4 - 2.42E+06 - - - 2.2686 - 1.227 0.35 - 210.2 1 2 0 0.0028 11 0 0 0 0.00E+00 0.00E+00 - - - 2.1786 0.8994 230117_WJC_METTL3_WT_vs_EV_F02.22405.22405.3 0.12 Sep-52 R.KYHISALYVVDLK[136.11]K[136.11].F "sp|Q9NYU1|UGGG2_HUMAN,sp|Q9NYU2|UGGG1_HUMAN" 2 1691.9945 - 18129 22405 3 1691.990507 565.0055 UDP-glucose:glycoprotein glucosyltransferase 2 OS=Homo sapiens OX=9606 GN=UGGT2 PE=1 SV=4 9.4 3992.9 - 1.54E+06 - - - -2.3765 - 1.515 0.133 - 38 1 2 0 -0.004 14 0 0 0 - - - - - 1.1257 1 230117_WJC_METTL3_WT_vs_EV_F02.22406.22406.2 3.31E-09 19/32 R.AFLQGGQEATDIALLLR[166.11].D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1824.9973 -1 18130 22406 2 1824.997402 913.5059 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3993 - 1.26E+06 - - - 0.046 - 3.685 0.663 - 1214.1 1 2 0 0.0001 17 0 0 0 0.00E+00 0.00E+00 - - - 7.1445 1 230117_WJC_METTL3_WT_vs_EV_F02.22407.22407.2 7.71E-05 13/24 R.DPTYFGPVLNYLR.H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1553.7878 0.74 18131 22407 2 1553.78938 777.9012 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3993.2 - 952774 - - - 0.9982 - 2.647 0.543 - 670.6 1 2 0 0.0016 13 0 0 0 7.35E+06 9.96E+06 - - - 5.5494 1 230117_WJC_METTL3_WT_vs_EV_F02.22413.22413.2 3.91E-09 14/22 K.FFDDPMLLELAK.Q "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1437.7214 -1 18136 22413 2 1437.722552 719.868 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.03 3993.7 - 3.83E+06 - - - 0.8089 - 2.6 0.606 - 357.6 1 2 0 0.0012 12 0 0 0 0.00E+00 0.00E+00 - - - 6.0307 1 230117_WJC_METTL3_WT_vs_EV_F02.22414.22414.2 2.59E-05 13/22 R.SQALIEELLLYK.R sp|Q5VT52|RPRD2_HUMAN 1 1418.8021 -1 18137 22414 2 1418.804618 710.4083 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3993.8 - 2.80E+06 - - - 1.7874 - 2.543 0.439 - 517.1 1 2 0 0.0025 12 0 0 0 0.00E+00 0.00E+00 - - - 4.7384 1 230117_WJC_METTL3_WT_vs_EV_F02.22415.22415.3 2.81E-09 13/52 R.HPYFYAPELLFFAK.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 1741.8868 -1 18138 22415 3 1741.891569 581.6362 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6.75 3993.8 - 2.65E+06 - - - 2.7292 - 2.856 0.592 - 258.3 1 2 0 0.0048 14 0 0 0 0.00E+00 0.00E+00 - - - 7.9278 1 230117_WJC_METTL3_WT_vs_EV_F02.22416.22416.3 1.26E-05 16/52 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 8.98 18139 22416 3 1537.772328 513.5972 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3993.9 - 2.22E+06 - - - 1.6465 - 3.114 0.552 - 434.4 1 2 0 0.0025 14 0 0 0 1.65E+07 1.84E+06 - - - 7.7123 1 230117_WJC_METTL3_WT_vs_EV_F02.22417.22417.3 4.15E-07 19/60 K.IFEIFGPVAHPFYVLR.F sp|Q96HR8|NAF1_HUMAN 1 1904.0349 -1 18140 22417 3 1904.038628 635.6856 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 6.75 3993.9 - 2.19E+06 - - - 1.9706 - 3.488 0.52 - 510.9 1 2 0 0.0038 16 0 0 0 0.00E+00 0.00E+00 - - - 7.5421 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22419.22419.3 6.18E-06 17/60 K.IFEIFGPVAHPFYVLR[166.11].F sp|Q96HR8|NAF1_HUMAN 1 1914.0431 -1 18142 22419 3 1914.043516 639.0217 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 6.75 3994.1 - 1.89E+06 - - - 0.1933 - 2.991 0.282 - 278.3 1 2 0 0.0004 16 0 0 0 0.00E+00 0.00E+00 - - - 4.4951 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.22420.22420.3 0.03 Sep-52 R.VISGVLQLGNIVFK[136.11].K sp|P35579|MYH9_HUMAN 1 1493.9061 -1 18143 22420 3 1493.908395 498.976 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.72 3994.1 - 1.65E+06 - - - 1.5356 - 1.97 0.328 - 77.1 1 2 0 0.0023 14 0 0 0 0.00E+00 0.00E+00 - - - 3.9981 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.22421.22421.2 0.000107 22-Dec R.SQALIEELLLYK[136.11].R sp|Q5VT52|RPRD2_HUMAN 1 1426.8163 1.31 18144 22421 2 1426.818471 714.4154 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3994.2 - 1.61E+06 - - - 1.5342 - 2.156 0.359 - 404.3 1 2 0 0.0022 12 0 0 0 4.67E+06 3.55E+06 - - - 3.7133 0.9115 230117_WJC_METTL3_WT_vs_EV_F02.22423.22423.2 1.36E-06 15/26 K.DAAGIAMEAIAFAR.N sp|P08240|SRPRA_HUMAN 1 1405.7024 -1 18146 22423 2 1405.713748 703.8585 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 4.37 3994.4 - 1.20E+06 - - - 8.0835 - 2.367 0.059 - 618.9 1 2 0 0.0114 14 0 0 0 0.00E+00 0.00E+00 - - - 1.6354 1 230117_WJC_METTL3_WT_vs_EV_F02.22424.22424.2 0.000142 15/26 K.TLAESALQLLYTAK.E sp|Q9Y490|TLN1_HUMAN 1 1520.845 -1 18147 22424 2 1520.84615 761.4298 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.66 3994.5 - 989502 - - - 0.7496 - 2.234 0.503 - 532.5 1 2 0 0.0011 14 0 0 0 0.00E+00 0.00E+00 - - - 4.7729 1 230117_WJC_METTL3_WT_vs_EV_F02.22425.22425.2 1.55E-08 14/26 K.TLAESALQLLYTAK[136.11].E sp|Q9Y490|TLN1_HUMAN 1 1528.8592 -1 18148 22425 2 1528.865626 765.4369 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.66 3994.6 - 981012 - - - 4.1966 - 2.636 0.594 - 412.9 1 2 0 0.0064 14 0 0 0 0.00E+00 0.00E+00 - - - 5.8586 1 230117_WJC_METTL3_WT_vs_EV_F02.22426.22426.3 4.51E-08 20/56 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 2.29 18149 22426 3 1519.91006 507.6435 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3994.6 - 869260 - - - 0.952 - 2.739 0.539 - 545 1 2 0 0.0014 15 0 0 0 1.28E+07 5.58E+06 - - - 7.1781 1 230117_WJC_METTL3_WT_vs_EV_F02.22427.22427.2 2.00E-07 13/26 K.LLETIDQLYLEYAK.R "sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|H7C5W8|H7C5W8_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|H0YJ11|H0YJ11_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN" 13 1710.908 -1 18150 22427 2 1710.910984 856.4613 Alpha-actinin-1 OS=Homo sapiens OX=9606 GN=ACTN1 PE=1 SV=2 4.14 3994.8 - 808668 - - - 1.7418 - 2.609 0.56 - 383.6 1 2 0 0.003 14 0 0 0 0.00E+00 0.00E+00 - - - 5.5827 0.9955 230117_WJC_METTL3_WT_vs_EV_F02.22431.22431.3 0.000946 Nov-52 K.DAAGIAMEAIAFAR.N sp|P08240|SRPRA_HUMAN 1 1405.7024 -1 18153 22431 3 1405.71171 469.5747 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 4.37 3995.2 - 343138 - - - 6.6337 - 1.855 0.387 - 72.2 1 2 0 0.0093 14 0 0 0 0.00E+00 0.00E+00 - - - 4.4941 1 230117_WJC_METTL3_WT_vs_EV_F02.22433.22433.2 6.59E-07 26-Nov K.DMLEAGILDTYLGK[136.11].Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1545.784 -1 18155 22433 2 1545.785863 773.8993 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3995.3 - 6.76E+06 - - - 1.2078 - 2.73 0.615 - 302.3 1 2 0 0.0019 14 0 0 0 0.00E+00 0.00E+00 - - - 6.103 1 230117_WJC_METTL3_WT_vs_EV_F02.22434.22434.2 0.00329 16/28 R.ATSFLLALEPELEAR.L "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1658.8879 -1 18156 22434 2 1658.888362 830.4512 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.25 3995.4 - 4.39E+06 - - - 0.2562 - 2.884 0.517 - 871.3 1 2 0 0.0004 15 0 0 0 0.00E+00 0.00E+00 - - - 5.4635 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.22435.22435.3 0.00935 Dec-56 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 2.29 18157 22435 3 1529.91864 510.9796 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3995.4 - 2.00E+06 - - - 1.1484 - 2.411 0.441 - 161 1 2 0 0.0018 15 0 0 0 1.28E+07 5.58E+06 - - - 5.7526 1 230117_WJC_METTL3_WT_vs_EV_F02.22437.22437.2 1.54E-07 19/28 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 3.1 18159 22437 2 1519.911446 760.9616 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3995.5 - 1.70E+06 - - - 1.8639 - 3.106 0.614 - 1532.3 1 2 0 0.0028 15 0 0 0 7.23E+06 2.34E+06 - - - 6.3615 1 230117_WJC_METTL3_WT_vs_EV_F02.22439.22439.2 0.000443 14/24 K.TVYVSVLPTTADF.- "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN" 4 1411.7235 - 18161 22439 2 1411.726383 706.869 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 3.8 3995.7 - 1.49E+06 - - - 2.0436 - 2.206 0.511 - 677.6 1 2 0 0.0029 13 0 0 0 - - - - - 4.8449 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.22440.22440.3 0.000936 Sep-48 R.GNTAAYLLYAFTR.L sp|P54136|SYRC_HUMAN 1 1459.746 -1 18162 22440 3 1459.747615 487.5893 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.59 3995.8 - 1.48E+06 - - - 1.1303 - 1.908 0.332 - 88.9 1 2 0 0.0016 13 0 0 0 0.00E+00 0.00E+00 - - - 3.9927 1 230117_WJC_METTL3_WT_vs_EV_F02.22442.22442.2 5.76E-16 24/36 R.LPVVIGGLLDVDC[160.03]SEDVIK.N "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2040.0813 -1 18164 22442 2 2040.086295 1021.0479 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 3.84 3996 - 1.05E+06 - - - 2.4514 - 4.43 0.776 - 1720.5 1 2 0 0.005 19 0 0 0 0.00E+00 0.00E+00 - - - 8.4303 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.22443.22443.3 0.00128 Oct-48 R.GNTAAYLLYAFTR[166.11].L sp|P54136|SYRC_HUMAN 1 1469.7542 -1 18165 22443 3 1469.754623 490.9254 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.59 3996.1 - 1.00E+06 - - - 0.264 - 1.82 0.353 - 111 1 2 0 0.0004 13 0 0 0 0.00E+00 0.00E+00 - - - 4.0991 1 230117_WJC_METTL3_WT_vs_EV_F02.22444.22444.2 3.59E-05 24-Nov R.LLDEWFTLDEVPK[136.11].G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1611.8276 -1 18166 22444 2 1611.832823 806.9211 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 3.92 3996.2 - 913240 - - - 3.2559 - 2.5 0.448 - 282.5 1 2 0 0.0052 13 0 0 0 0.00E+00 0.00E+00 - - - 4.7 1 230117_WJC_METTL3_WT_vs_EV_F02.22446.22446.2 0.00014 20-Nov K.IADFGFGNFFK.S sp|Q9H0K1|SIK2_HUMAN 1 1261.6132 -1 18168 22446 2 1261.613881 631.8139 Serine\threonine-protein kinase SIK2 OS=Homo sapiens OX=9606 GN=SIK2 PE=1 SV=1 5.84 3996.5 - 678496 - - - 0.5723 - 2.497 0.44 - 495.5 1 2 0 0.0007 11 0 0 0 0.00E+00 0.00E+00 - - - 4.7661 1 230117_WJC_METTL3_WT_vs_EV_F02.22448.22448.2 1.10E-13 20/36 R.LPVVIGGLLDVDC[160.03]SEDVIK[136.11].N "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2048.0955 -1 18170 22448 2 2048.097712 1025.055 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 3.84 3996.8 - 668380 - - - 1.083 - 4.098 0.749 - 1155.5 1 2 0 0.0022 19 0 0 0 0.00E+00 0.00E+00 - - - 8.0402 1 230117_WJC_METTL3_WT_vs_EV_F02.22455.22455.3 4.65E-05 17/52 K.ILGGSVLHLVLALR.G sp|Q15843|NEDD8_HUMAN 1 1459.9239 -1 18176 22455 3 1459.928752 487.6486 NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1 9.76 3997.5 - 4.55E+06 - - - 3.3447 - 2.917 0.573 - 436.4 1 2 0 0.0049 14 0 0 0 0.00E+00 0.00E+00 - - - 7.7721 1 230117_WJC_METTL3_WT_vs_EV_F02.22456.22456.2 9.85E-07 15/22 K.AILC[160.03]LLLGGVER.D "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1312.7537 -1 18177 22456 2 1312.757944 657.3841 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 6.04 3997.5 - 2.68E+06 - - - 3.2382 - 2.615 0.516 - 1220.6 1 2 0 0.0043 12 0 0 0 0.00E+00 0.00E+00 - - - 5.3801 1 230117_WJC_METTL3_WT_vs_EV_F02.22457.22457.3 8.66E-08 21/52 K.ILGGSVLHLVLALR[166.11].G sp|Q15843|NEDD8_HUMAN 1 1469.9321 -1 18178 22457 3 1469.937041 490.9847 NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1 9.76 3997.6 - 2.41E+06 - - - 3.3348 - 3.158 0.582 - 733.2 1 2 0 0.0049 14 0 0 0 0.00E+00 0.00E+00 - - - 8.0834 1 230117_WJC_METTL3_WT_vs_EV_F02.22459.22459.2 8.04E-06 22-Nov K.AYVVLGQFLVLK[136.11].K sp|O75531|BAF_HUMAN 1 1356.8261 -1 18180 22459 2 1356.830715 679.4203 Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1 8.63 3997.7 - 1.84E+06 - - - 3.4315 - 2.264 0.533 - 405 1 2 0 0.0047 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1263 1 230117_WJC_METTL3_WT_vs_EV_F02.22461.22461.2 4.97E-06 22-Nov K.AYVVLGQFLVLK.K sp|O75531|BAF_HUMAN 1 1348.8119 -1 18182 22461 2 1348.815814 675.4132 Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1 8.63 3997.9 - 1.11E+06 - - - 2.9322 - 2.269 0.496 - 380.2 1 2 0 0.004 12 0 0 0 0.00E+00 0.00E+00 - - - 4.859 1 230117_WJC_METTL3_WT_vs_EV_F02.22467.22467.2 3.61E-07 17/28 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 -1 18188 22467 2 1529.923546 765.9657 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3998.7 - 847704 - - - 4.3551 - 2.984 0.609 - 920.6 1 2 0 0.0067 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2248 0.9998 230117_WJC_METTL3_WT_vs_EV_F02.22468.22468.3 0.000577 18/64 K.ALQDEWDAVMLHSFTLR[166.11].Q "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2040.9967 -1 18189 22468 3 2041.002645 681.3395 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.54 3998.8 - 829790 - - - 2.929 - 2.437 0.399 - 427.3 1 2 0 0.006 17 0 0 0 0.00E+00 0.00E+00 - - - 5.2371 0.9997 230117_WJC_METTL3_WT_vs_EV_F02.22475.22475.3 0.00225 Sep-56 R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 2.21 18195 22475 3 1555.904322 519.6409 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3999.5 - 1.65E+08 - - - 2.2951 - 1.853 0.393 - 78.4 1 2 0 0.0036 15 0 0 0 1.94E+08 8.75E+07 - - - 4.53 1 230117_WJC_METTL3_WT_vs_EV_F02.22476.22476.3 5.46E-06 Nov-56 R.GVMLAVDAVIAELK[136.11]K[136.11].Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1571.9292 -1 18196 22476 3 1571.93087 524.9837 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3999.5 - 7.44E+07 - - - 1.0936 - 2.476 0.595 - 127.1 1 2 0 0.0017 15 0 0 0 0.00E+00 0.00E+00 - - - 7.539 1 230117_WJC_METTL3_WT_vs_EV_F02.22477.22477.3 3.80E-06 19/56 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 -1 18197 22477 3 1581.910328 528.3103 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 3999.6 - 5.54E+07 - - - 0.8351 - 3.211 0.475 - 706.3 1 2 0 0.0013 15 0 0 0 0.00E+00 0.00E+00 - - - 6.8795 1 230117_WJC_METTL3_WT_vs_EV_F02.22479.22479.2 5.56E-06 14/28 R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 -1 18199 22479 2 1555.902925 778.9577 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3999.7 - 1.88E+07 - - - 1.3973 - 3.029 0.528 - 609.3 1 2 0 0.0022 15 0 0 0 0.00E+00 0.00E+00 - - - 5.6648 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.23119.23119.2 0.0961 16-Nov R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.45 18239 23119 2 1108.654184 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4124 - 3.46E+07 - - - 0.8578 - 2.247 0.243 - 303 1 2 0 0.0009 9 0 0 0 1.89E+08 1.31E+08 - - - 3.1777 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.23120.23120.2 0.00225 16-Oct R.IAIYELLFK[136.11].E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1116.6674 1.45 18240 23120 2 1116.667952 559.341 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4124 - 2.28E+07 - - - 0.4648 - 2.168 0.306 - 250.1 1 2 0 0.0005 9 0 0 0 1.89E+08 1.31E+08 - - - 3.5396 1 230117_WJC_METTL3_WT_vs_EV_F02.23126.23126.2 2.50E-06 14/26 K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.43 18246 23126 2 1618.968398 810.4902 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4124.5 - 4.66E+06 - - - 1.6084 - 2.446 0.544 - 330.8 1 2 0 0.0026 14 0 0 0 2.56E+07 1.78E+07 - - - 5.3028 1 230117_WJC_METTL3_WT_vs_EV_F02.23128.23128.2 0.0495 20/28 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 7.24 18248 23128 2 1581.91146 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4124.7 - 4.56E+06 - - - 1.5507 - 3.586 0.487 - 1377.4 1 2 0 0.0025 15 0 0 0 2.66E+07 3.68E+06 - - - 5.7769 1 230117_WJC_METTL3_WT_vs_EV_F02.23130.23130.2 5.04E-11 20/28 R.LTSFIGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1516.8865 5.83 18250 23130 2 1516.88857 759.4505 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 4124.9 - 4.20E+06 - - - 1.3772 - 3.249 0.603 - 1241.8 1 2 0 0.0021 15 0 0 0 2.48E+07 4.25E+06 - - - 6.3911 1 230117_WJC_METTL3_WT_vs_EV_F02.23132.23132.3 2.09E-08 20/56 R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 6.81 18252 23132 3 1555.903445 519.6409 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 4125.1 - 3.99E+06 - - - 1.7315 - 3.507 0.58 - 426.4 1 2 0 0.0027 15 0 0 0 2.93E+07 4.31E+06 - - - 8.2798 1 230117_WJC_METTL3_WT_vs_EV_F02.23133.23133.3 4.14E-05 28/56 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 6.67 18253 23133 3 1581.911659 528.3103 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4125.1 - 3.99E+06 - - - 1.6765 - 4.221 0.571 - 1638.6 1 2 0 0.0027 15 0 0 0 1.85E+07 2.76E+06 - - - 8.663 1 230117_WJC_METTL3_WT_vs_EV_F02.23135.23135.2 7.85E-05 14/26 K.ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1626.98 -1 18255 23135 2 1626.980854 814.4973 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4125.4 - 3.14E+06 - - - 0.5286 - 2.446 0.478 - 450 1 2 0 0.0009 14 0 0 0 0.00E+00 0.00E+00 - - - 4.8158 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.23137.23137.3 8.11E-05 Dec-52 R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 3.33 18257 23137 3 1486.873415 496.6312 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4125.5 - 2.45E+06 - - - 1.0236 - 2.341 0.478 - 223.1 1 2 0 0.0015 14 0 0 0 1.05E+07 3.14E+06 - - - 6.1292 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.23138.23138.2 2.68E-05 20-Dec K.GIVLLEELLPK.G sp|Q9Y3D6|FIS1_HUMAN 1 1222.7537 -1 18258 23138 2 1222.756782 612.3841 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 4.53 4125.6 - 2.26E+06 - - - 2.5402 - 2.32 0.44 - 587.7 1 2 0 0.0031 11 0 0 0 0.00E+00 0.00E+00 - - - 4.5665 1 230117_WJC_METTL3_WT_vs_EV_F02.23140.23140.2 4.78E-11 23/30 K.LGFAGLVQEISFGTTK.D "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1666.893 4.03 18259 23140 2 1666.894738 834.4538 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 4126 - 1.51E+06 - - - 1.0289 - 3.856 0.597 - 1585.9 1 2 0 0.0017 16 0 0 0 1.33E+07 3.29E+06 - - - 6.768 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.23141.23141.3 1.44E-05 Dec-52 K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.99 18260 23141 3 1618.969443 540.6625 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4126.1 - 1.09E+06 - - - 2.2539 - 2.404 0.47 - 162.2 1 2 0 0.0036 14 0 0 0 9.96E+06 5.00E+06 - - - 6.11 1 230117_WJC_METTL3_WT_vs_EV_F02.23143.23143.2 0.00283 16/26 R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 3.34 18262 23143 2 1486.872736 744.4432 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4126.4 - 1.20E+06 - - - 0.567 - 2.795 0.519 - 812.9 1 2 0 0.0008 14 0 0 0 1.43E+07 4.27E+06 - - - 5.4534 1 230117_WJC_METTL3_WT_vs_EV_F02.23145.23145.3 5.32E-06 14/52 K.ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1626.98 1.99 18264 23145 3 1626.980551 543.3339 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4126.6 - 805245 - - - 0.3424 - 2.441 0.554 - 277.5 1 2 0 0.0006 14 0 0 0 9.96E+06 5.00E+06 - - - 7.088 1 230117_WJC_METTL3_WT_vs_EV_F02.23147.23147.2 4.14E-05 24-Dec K.SLEEIYLFSLPIK[136.11].E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN,tr|H3BNG3|H3BNG3_HUMAN,tr|H0YE27|H0YE27_HUMAN" 7 1558.8738 -1 18266 23147 2 1558.873888 780.4442 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.53 4126.9 - 691214 - - - 0.0584 - 2.663 0.515 - 433.9 1 2 0 0.0001 13 0 0 0 0.00E+00 0.00E+00 - - - 5.3586 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.23148.23148.2 0.000478 26-Nov R.APIASIHSFELDLL.- sp|Q13015|AF1Q_HUMAN 1 1524.8188 - 18267 23148 2 1524.817936 763.4167 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 4.35 4127 - 667163 - - - -0.5633 - 2.094 0.465 - 427.7 1 2 0 -0.0009 14 0 0 0 - - - - - 4.3299 1 230117_WJC_METTL3_WT_vs_EV_F02.23149.23149.2 8.34E-06 13/24 K.SLEEIYLFSLPIK.E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN,tr|H3BNG3|H3BNG3_HUMAN,tr|H0YE27|H0YE27_HUMAN" 7 1550.8596 -1 18268 23149 2 1550.872785 776.4371 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.53 4127.2 - 625877 - - - 8.5037 - 2.346 0.554 - 437.2 1 2 0 0.0132 13 0 0 0 0.00E+00 0.00E+00 - - - 5.3172 1 230117_WJC_METTL3_WT_vs_EV_F02.23150.23150.2 0.000243 28-Sep R.QVLLSAAEAAEVILR[166.11].V sp|P78371|TCPB_HUMAN 1 1591.9173 7.23 18269 23150 2 1591.919038 796.9659 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4127.3 - 591065 - - - 1.1062 - 2.517 0.461 - 229.4 1 2 0 0.0018 15 0 0 0 2.66E+07 3.68E+06 - - - 4.7148 1 230117_WJC_METTL3_WT_vs_EV_F02.23152.23152.2 4.38E-08 Dec-32 R.WVGGPEIELIAIATGGR.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1737.9414 -1 18271 23152 2 1737.941125 869.978 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 4127.6 - 476899 - - - -0.141 - 2.482 0.675 - 411.2 1 2 0 -0.0002 17 0 0 0 0.00E+00 0.00E+00 - - - 6.2615 0.9993 230117_WJC_METTL3_WT_vs_EV_F02.23153.23153.3 0.00236 Jul-56 R.LTSFIGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1516.8865 7.03 18272 23153 3 1516.887544 506.6361 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 4127.7 - 472048 - - - 0.7008 - 1.404 0.364 - 54.6 1 2 0 0.0011 15 0 0 0 3.61E+06 5.14E+05 - - - 3.4834 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.23155.23155.2 0.000212 22-Jul R.TFC[160.03]QLILDPIFK.V sp|P13639|EF2_HUMAN 1 1493.7952 -1 18274 23155 2 1493.799532 747.9049 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.5 4128 - 365023 - - - 2.8846 - 1.628 0.523 - 135 1 2 0 0.0043 12 0 0 0 0.00E+00 0.00E+00 - - - 4.1848 0.9996 230117_WJC_METTL3_WT_vs_EV_F02.23156.23156.2 0.000905 26-Jun R.LLVPTQFVGAIIGK[136.11].E "sp|O00425|IF2B3_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 3 1462.9003 -1 18275 23156 2 1462.900783 732.4574 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 4128.1 - 344504 - - - 0.3391 - 1.676 0.523 - 76.8 1 2 0 0.0005 14 0 0 0 0.00E+00 0.00E+00 - - - 4.1996 0.9972 230117_WJC_METTL3_WT_vs_EV_F02.23157.23157.2 0.0832 20-May K.GIVLLEELLPK[136.11].G sp|Q9Y3D6|FIS1_HUMAN 1 1230.7679 -1 18276 23157 2 1230.769272 616.3912 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 4.53 4128.2 - 341497 - - - 1.1343 - 1.03 0.313 - 75.7 1 2 0 0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 1.4323 0.9986 230117_WJC_METTL3_WT_vs_EV_F02.23159.23159.2 0.146 28-Apr K.FDVILLEPPLEEYYR.E "sp|Q9HCE5|MET14_HUMAN,tr|D6RBL4|D6RBL4_HUMAN" 2 1894.9717 -1 18278 23159 2 1894.972818 948.4931 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4 4128.5 - 311985 - - - 0.6074 - 1.164 0.377 - 28.2 1 2 0 0.0012 15 0 0 0 0.00E+00 0.00E+00 - - - 2.1985 1 230117_WJC_METTL3_WT_vs_EV_F02.23187.23187.2 6.37E-06 Nov-32 R.AQLGVQAFADALLIIPK.V sp|P40227|TCPZ_HUMAN 1 1767.0295 -1 18284 23187 2 1767.044841 884.522 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.88 4132.4 - 226275 - - - 8.7061 - 2.903 0.567 - 259.4 1 2 0 0.0154 17 0 0 0 0.00E+00 0.00E+00 - - - 5.8442 1 230117_WJC_METTL3_WT_vs_EV_F02.23316.23316.2 0.0344 28-Dec R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 7.65 18296 23316 2 1581.914209 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4157.2 - 0 - - - 3.2884 - 2.664 0.541 - 519.1 1 2 0 0.0052 15 0 0 0 3.54E+07 4.62E+06 - - - 5.4441 1 230117_WJC_METTL3_WT_vs_EV_F02.23372.23372.2 0.0111 26-Nov R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 6.21 18309 23372 2 1486.875121 744.4432 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4166.5 - 0 - - - 2.171 - 2.483 0.45 - 395.8 1 2 0 0.0032 14 0 0 0 3.87E+06 6.22E+05 - - - 4.6459 0.999 230117_WJC_METTL3_WT_vs_EV_F02.23378.23378.2 0.000145 24-Jul K.SLEEIYLFSLPIK[136.11].E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN,tr|H3BNG3|H3BNG3_HUMAN,tr|H0YE27|H0YE27_HUMAN" 7 1558.8738 0.16 18312 23378 2 1558.87948 780.4442 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.53 4167.3 - 0 - - - 3.6456 - 1.482 0.504 - 139.2 1 2 0 0.0057 13 0 0 0 4.54E+05 2.78E+06 - - - 3.7714 0.9994 230117_WJC_METTL3_WT_vs_EV_F02.23388.23388.2 0.0101 28-Sep R.QVLLSAAEAAEVILR[166.11].V sp|P78371|TCPB_HUMAN 1 1591.9173 7.65 18316 23388 2 1591.921421 796.9659 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4168.7 - 0 - - - 2.6032 - 2.192 0.358 - 267.6 1 2 0 0.0041 15 0 0 0 3.54E+07 4.62E+06 - - - 3.6134 0.9995 230117_WJC_METTL3_WT_vs_EV_F02.23502.23502.2 0.132 28-Sep R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 7.65 18339 23502 2 1581.913778 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4187.9 - 0 - - - 3.016 - 2.258 0.465 - 287.1 1 2 0 0.0048 15 0 0 0 3.54E+07 4.62E+06 - - - 4.4764 0.9999 230117_WJC_METTL3_WT_vs_EV_F02.23503.23503.3 0.00549 15/56 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 6.86 18340 23503 3 1581.913962 528.3103 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4188 - 5101.27 - - - 3.1323 - 2.752 0.46 - 455.4 1 2 0 0.005 15 0 0 0 2.33E+07 3.39E+06 - - - 6.3087 0.9965 230117_WJC_METTL3_WT_vs_EV_F02.23512.23512.2 0.263 16-Jul R.IAIYELLFK[136.11].E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1116.6674 1.48 18343 23512 2 1116.670999 559.341 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4189.5 - 4507.94 - - - 3.1934 - 1.725 0.189 - 118.7 2 2 0 0.0036 9 0 0 0 6.27E+07 4.24E+07 - - - 1.8787 0.998 230117_WJC_METTL3_WT_vs_EV_F02.23515.23515.2 0.00195 16-Oct R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.48 18344 23515 2 1108.65801 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4189.9 - 22084.5 - - - 4.3088 - 2.152 0.285 - 261 1 2 0 0.0048 9 0 0 0 6.27E+07 4.24E+07 - - - 3.3617 0.9752 230117_WJC_METTL3_WT_vs_EV_F03.03609.03609.2 2.29 14-May K.SFATASHR.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 875.425 0.77 18369 3609 2 875.426459 438.7198 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.49 1400.2 - 59385.1 - - - 1.7066 - 0.848 0.181 - 82.7 1 2 0 0.0015 8 0 0 0 1.68E+06 2.19E+06 - - - -0.1199 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.04127.04127.2 0.105 12-Jul R.NSTIPTK.Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 759.4127 8.19 18388 4127 2 759.413815 380.7136 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 1492.8 - 588211 - - - 1.5091 - 1.417 0.202 - 209.8 1 2 0 0.0011 7 0 0 0 2.21E+07 2.70E+06 - - - 1.637 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.04140.04140.2 0.345 12-Jun R.FTDEESR[166.11].V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 892.3802 0.7 18389 4140 2 892.380547 447.1974 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1495.1 - 963151 - - - 0.3933 - 1.154 0.288 - 120.4 1 2 0 0.0004 7 0 0 0 1.71E+07 2.43E+07 - - - 1.6219 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.04142.04142.2 0.000181 18-Nov R.IAGQVAAANK.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 941.5294 1.51 18390 4142 2 941.530258 471.772 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1495.4 - 391736 - - - 0.8794 - 2.218 0.406 - 312 1 2 0 0.0008 10 0 0 0 1.14E+07 7.60E+06 - - - 4.263 0.9156 230117_WJC_METTL3_WT_vs_EV_F03.04202.04202.2 4.34 14-May R.NTEEEGLK[136.11].Y "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 926.4436 1.43 18393 4202 2 926.442856 464.2291 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.25 1506 - 152350 - - - -0.8473 - 0.904 0.119 - 69.6 1 2 0 -0.0008 8 0 0 0 2.98E+07 2.09E+07 - - - -0.3847 0.9748 230117_WJC_METTL3_WT_vs_EV_F03.04243.04243.2 1.24 12-Jun R.EAQVNVR[166.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 824.438 0.05 18394 4243 2 824.437708 413.2263 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1513.2 - 503774 - - - -0.3372 - 1.205 0.081 - 254.9 1 2 0 -0.0003 7 0 0 0 1.38E+07 2.64E+08 - - - 0.23 0.9961 230117_WJC_METTL3_WT_vs_EV_F03.04248.04248.2 0.0738 12-Jun R.EAQVNVR.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 814.4297 0.05 18395 4248 2 814.42915 408.2221 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1514 - 408886 - - - -0.695 - 1.299 0.266 - 168.8 1 2 0 -0.0006 7 0 0 0 1.39E+07 2.63E+08 - - - 1.8344 0.9773 230117_WJC_METTL3_WT_vs_EV_F03.04503.04503.2 0.321 16-Apr K.VLENAEGAR.T "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 957.488 15.76 18408 4503 2 957.487986 479.7513 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.53 1558.2 - 143591 - - - 0.0282 - 0.923 0.212 - 48.4 3 2 0 0 9 0 0 0 4.33E+06 2.75E+05 - - - 0.1619 0.9938 230117_WJC_METTL3_WT_vs_EV_F03.04510.04510.2 0.214 14-Jul K.SVLADQGK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 816.4341 0.39 18410 4510 2 816.434522 409.2243 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.55 1559.2 - 1.49E+07 - - - 0.4777 - 1.129 0.207 - 135.5 1 2 0 0.0004 8 0 0 0 2.78E+07 7.20E+07 - - - 0.9357 0.9158 230117_WJC_METTL3_WT_vs_EV_F03.04946.04946.2 1.43 14-May R.TSIEVGVK.G sp|Q03052|PO3F1_HUMAN 1 831.4702 999 18416 4946 2 831.472408 416.7424 "POU domain, class 3, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU3F1 PE=2 SV=3" 5.66 1638.6 - 1.47E+06 - - - 2.676 - 1.047 0.061 - 72 5 2 0 0.0022 8 0 0 0 2.10E+09 0.00E+00 - - - -0.6829 0.9904 230117_WJC_METTL3_WT_vs_EV_F03.05008.05008.2 0.0939 16-Jul K.TIAPQNAPR.D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 966.5247 0.16 18418 5008 2 966.524318 484.2696 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1649.8 - 205685 - - - -0.3735 - 1.289 0.157 - 170.8 1 2 0 -0.0004 9 0 0 0 2.57E+07 1.60E+08 - - - 0.9349 0.9843 230117_WJC_METTL3_WT_vs_EV_F03.05031.05031.2 0.0771 16-Sep K.TIAPQNAPR[166.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 976.5329 0.15 18419 5031 2 976.531863 489.2738 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1653.8 - 777152 - - - -1.1121 - 1.336 0.14 - 238.7 1 2 0 -0.0011 9 0 0 0 2.57E+07 1.68E+08 - - - 0.9128 0.9779 230117_WJC_METTL3_WT_vs_EV_F03.05149.05149.2 0.832 12-Jul K.LVEESVK[136.11].H "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 810.4578 0.38 18421 5149 2 810.45547 406.2362 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 1674.4 - 548560 - - - -2.9169 - 1.563 0.147 - 174.4 1 2 0 -0.0024 7 0 0 0 8.11E+06 2.12E+07 - - - 1.5411 0.9941 230117_WJC_METTL3_WT_vs_EV_F03.05505.05505.2 3.24 12-Jul K.ITITNDK.G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 803.4389 12.59 18432 5505 2 803.440423 402.7267 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1738.3 - 382635 - - - 1.9168 - 1.214 0.169 - 173 1 2 0 0.0015 7 0 0 0 1.15E+08 9.12E+06 - - - 0.9032 0.9855 230117_WJC_METTL3_WT_vs_EV_F03.05511.05511.2 0.262 12-May K.ITITNDK[136.11].G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 811.4531 12.58 18433 5511 2 811.45611 406.7338 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1739.3 - 69012.2 - - - 3.7303 - 1.082 0.228 - 86.8 1 2 0 0.003 7 0 0 0 1.15E+08 9.12E+06 - - - 0.9738 0.9908 230117_WJC_METTL3_WT_vs_EV_F03.05518.05518.2 0.0536 14-Aug K.EHC[160.03]LVGVK.G sp|Q86U44|MTA70_HUMAN 1 940.48 65.2 18434 5518 2 940.484463 471.2473 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 1740.6 - 514792 - - - 4.7061 - 1.409 0.249 - 308.6 1 2 0 0.0044 8 0 0 0 6.84E+07 1.05E+06 - - - 1.9128 0.9725 230117_WJC_METTL3_WT_vs_EV_F03.05713.05713.2 2.1 16-Jun R.VADNSFDAK.R "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 965.4454 999 18436 5713 2 965.446621 483.73 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.21 1776 - 128155 - - - 1.2388 - 0.972 0.113 - 51.3 1 2 0 0.0012 9 0 0 0 5.34E+06 0.00E+00 - - - -0.2069 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.05775.05775.2 0.112 14-Jul K.LLEGEESR.L "sp|P08670|VIME_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P17661|DESM_HUMAN,sp|P05787|K2C8_HUMAN,sp|P41219|PERI_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 11 931.4611 1.77 18440 5775 2 931.462689 466.7378 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 1787.2 - 166461 - - - 1.7328 - 1.237 0.261 - 151 1 2 0 0.0016 8 0 0 0 6.65E+06 3.75E+06 - - - 1.6097 0.9946 230117_WJC_METTL3_WT_vs_EV_F03.05893.05893.2 0.676 12-Jun K.LAEPYGK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 776.4069 1.37 18444 5893 2 776.408193 389.2107 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1808.1 - 360466 - - - 1.7233 - 1.301 0.144 - 146.5 1 2 0 0.0013 7 0 0 0 1.55E+07 1.13E+07 - - - 0.9379 0.972 230117_WJC_METTL3_WT_vs_EV_F03.06055.06055.2 1.2 16-Jun R.VNGSLAVSR[166.11].A "sp|O75688|PPM1B_HUMAN,sp|P35813|PPM1A_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 5 911.5064 0.13 18450 6055 2 911.504819 456.7605 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 9.72 1836.1 - 82120.4 - - - -1.7345 - 1.37 0.111 - 114.6 1 2 0 -0.0016 9 0 0 0 6.27E+05 4.87E+06 - - - 0.7711 0.9533 230117_WJC_METTL3_WT_vs_EV_F03.06059.06059.2 2.61 18-Jul K.GSAITGPVAK[136.11].E "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 907.5218 1.68 18451 6059 2 907.521396 454.7682 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.75 1836.7 - 155924 - - - -0.4804 - 1.092 0.079 - 103 1 2 0 -0.0004 10 0 0 0 1.30E+07 7.72E+06 - - - -0.13 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.06237.06237.2 0.000212 16-Oct R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 2.15 18458 6237 2 969.513286 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1869.2 - 336798 - - - 1.4512 - 1.943 0.428 - 361 1 2 0 0.0014 9 0 0 0 7.00E+07 3.26E+07 - - - 4.1234 0.8512 230117_WJC_METTL3_WT_vs_EV_F03.06533.06533.2 0.0664 16-Jun Q.GLVLDHGAR.H "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN,tr|J3KRI6|J3KRI6_HUMAN" 3 936.5141 0.18 18466 6533 2 936.516325 469.2643 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 6.74 1922.3 - 73663 - - - 2.3609 - 1.466 0.232 - 121.4 1 1 0 0.0022 9 0 0 0 2.68E+06 1.51E+07 - - - 1.8606 0.9914 230117_WJC_METTL3_WT_vs_EV_F03.06661.06661.2 0.458 14-Jun K.VISELNGK.N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 858.4811 1.12 18472 6661 2 858.482375 430.2478 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1945.6 - 228250 - - - 1.505 - 1.016 0.202 - 119.7 1 2 0 0.0013 8 0 0 0 1.53E+07 1.37E+07 - - - 0.5804 0.999 230117_WJC_METTL3_WT_vs_EV_F03.06948.06948.2 0.0733 12-Aug R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 137.73 18484 6948 2 776.383645 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1995.5 - 1.23E+06 - - - 2.5013 - 1.59 0.3 - 239 1 2 0 0.0019 7 0 0 0 4.61E+09 3.35E+07 - - - 2.7256 0.9878 230117_WJC_METTL3_WT_vs_EV_F03.06953.06953.2 3.93 14-Jul R.GTLDPVEK.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 857.4494 12.54 18485 6953 2 857.450183 429.732 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.37 1996.3 - 350616 - - - 0.8572 - 1.211 0.102 - 134.4 1 2 0 0.0007 8 0 0 0 8.11E+07 6.47E+06 - - - 0.3715 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.07081.07081.2 0.00619 16-Sep K.SAAMTLNER.F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 991.4757 0.8 18492 7081 2 991.476047 496.7451 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 2018.7 - 398446 - - - 0.3702 - 1.837 0.423 - 348 1 2 0 0.0004 9 0 0 0 1.57E+07 1.95E+07 - - - 3.9245 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.07155.07155.2 0.568 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 1.63 18496 7155 2 776.381887 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2031.5 - 515703 - - - 0.237 - 1.478 0.207 - 176.1 1 2 0 0.0002 7 0 0 0 1.02E+08 6.28E+07 - - - 1.8078 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.07187.07187.2 0.00272 14-Aug K.GANPVEIR.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 854.461 1.91 18498 7187 2 854.461269 428.2378 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 2037.2 - 515879 - - - 0.2961 - 1.529 0.361 - 243.8 1 2 0 0.0003 8 0 0 0 5.59E+07 2.93E+07 - - - 2.9879 0.9715 230117_WJC_METTL3_WT_vs_EV_F03.07221.07221.2 0.0911 12-Jul R.IGVITNR[166.11].E sp|P62701|RS4X_HUMAN 1 781.4686 0.92 18500 7221 2 781.468895 391.7416 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2043.2 - 513550 - - - 0.4325 - 1.306 0 - 164.9 1 2 0 0.0003 7 0 0 0 1.87E+07 2.04E+07 - - - -0.1132 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.07232.07232.2 0.0603 14-Jul K.GANPVEIR[166.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 864.4693 1.91 18503 7232 2 864.471068 433.2419 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 2044.8 - 526657 - - - 2.0614 - 1.245 0.35 - 178.1 1 2 0 0.0018 8 0 0 0 5.59E+07 2.92E+07 - - - 2.2864 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.07253.07253.2 0.122 14-Aug K.VGEVIVTK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.5208 2.01 18506 7253 2 851.52311 426.7677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2048.3 - 283324 - - - 2.7492 - 1.867 0.243 - 158.8 2 2 0 0.0023 8 0 0 0 1.04E+08 5.18E+07 - - - 2.5836 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.07271.07271.2 0.00985 14-Oct K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 2.01 18508 7271 2 843.50811 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2051.5 - 1.99E+06 - - - 1.8269 - 2.25 0.359 - 305.8 1 2 0 0.0015 8 0 0 0 1.04E+08 5.18E+07 - - - 4.1378 0.9853 230117_WJC_METTL3_WT_vs_EV_F03.07546.07546.2 1.12 16-Jun K.VTMQNLNDR.L "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 8 1089.5237 999 18524 7546 2 1089.523474 545.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.81 2099.2 - 159652 - - - -0.2001 - 1.185 0.156 - 91.8 2 2 0 -0.0002 9 0 0 0 5.93E+06 0.00E+00 - - - 0.5498 0.9061 230117_WJC_METTL3_WT_vs_EV_F03.07578.07578.3 0.276 Jul-44 R.TLVAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1299.763 0.27 18528 7578 3 1299.765433 434.2616 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2104.6 - 210367 - - - 1.9065 - 1.165 0.101 - 49 1 2 0 0.0025 12 0 0 0 3.40E+06 1.27E+07 - - - 0.0887 0.9954 230117_WJC_METTL3_WT_vs_EV_F03.07686.07686.2 0.32 16-Aug R.VLNTNIDGR[166.11].R "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1010.5384 1.54 18538 7686 2 1010.541941 506.2765 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.81 2123 - 167760 - - - 3.4764 - 1.376 0.245 - 174.7 1 2 0 0.0035 9 0 0 0 2.59E+07 1.68E+07 - - - 1.7729 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.07695.07695.2 0.00481 16-Aug R.VLNTNIDGR.R "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1000.5302 1.55 18540 7695 2 1000.530314 501.2724 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.81 2124.4 - 316427 - - - 0.1559 - 1.832 0.384 - 245.5 1 2 0 0.0002 9 0 0 0 2.59E+07 1.68E+07 - - - 3.6287 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.07718.07718.2 0.124 14-Jul R.VLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 815.4753 0.88 18544 7718 2 815.474867 408.7449 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 2127.9 - 500539 - - - -0.493 - 1.423 0.326 - 198.8 1 2 0 -0.0004 8 0 0 0 2.78E+07 3.15E+07 - - - 2.5126 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.07745.07745.2 0.171 16-Jun K.DVDGAYMTK.V sp|P04264|K2C1_HUMAN 1 998.4379 188.13 18548 7745 2 998.437183 500.2262 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.21 2132.3 - 151822 - - - -0.7151 - 1.264 0.406 - 91.2 1 2 0 -0.0007 9 0 0 0 6.13E+06 3.26E+04 - - - 2.7173 0.9922 230117_WJC_METTL3_WT_vs_EV_F03.07777.07777.2 2.54 14-Jul R.FSELTAEK.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 923.46 7.18 18552 7777 2 923.460674 462.7373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2137.6 - 527314 - - - 0.7158 - 1.091 0.19 - 99.4 1 2 0 0.0007 8 0 0 0 3.48E+07 4.84E+06 - - - 0.7068 0.9861 230117_WJC_METTL3_WT_vs_EV_F03.07796.07796.2 10.6 12-Jul R.IPPVAVR[166.11].L "sp|Q14839|CHD4_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A0G2JM70|A0A0G2JM70_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|V9GYG6|V9GYG6_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 760.4835 0.001 18556 7796 2 760.48447 381.249 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 2140.6 - 515091 - - - 1.3031 - 1.15 0.103 - 185.6 1 2 0 0.001 7 0 0 0 0.00E+00 1.43E+08 - - - 0.2443 0.9583 230117_WJC_METTL3_WT_vs_EV_F03.07849.07849.2 0.000553 16-Oct Y.PDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 953.5546 999 18558 7849 2 953.557514 477.7846 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2149.8 - 490708 - - - 3.0748 - 1.962 0.44 - 364.1 1 1 0 0.0029 9 0 0 0 2.92E+07 0.00E+00 - - - 4.2397 1 230117_WJC_METTL3_WT_vs_EV_F03.07883.07883.2 0.00109 18-Dec R.YPDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 1116.6179 610.6 18562 7883 2 1116.618973 559.3162 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2155.5 - 620163 - - - 0.952 - 2.105 0.55 - 416.5 1 2 0 0.0011 10 0 0 0 7.52E+07 1.23E+05 - - - 5.1806 0.8771 230117_WJC_METTL3_WT_vs_EV_F03.07892.07892.2 0.796 12-Jun D.VIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 784.4807 8.66 18564 7892 2 784.48114 393.2476 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 2156.9 - 1.37E+06 - - - 0.5749 - 1.368 0.26 - 179.9 1 1 0 0.0005 7 0 0 0 6.48E+07 7.48E+06 - - - 1.9541 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.07968.07968.2 0.000623 16-Sep R.TLLEGEESR.M sp|P04264|K2C1_HUMAN 1 1032.5088 56.76 18572 7968 2 1032.51032 517.2617 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.25 2169.9 - 847650 - - - 1.5167 - 1.663 0.384 - 252.1 1 2 0 0.0016 9 0 0 0 3.91E+07 6.89E+05 - - - 3.3482 0.9515 230117_WJC_METTL3_WT_vs_EV_F03.07973.07973.2 0.153 14-May K.HVVFIAQR.R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 968.5556 1.53 18574 7973 2 968.556892 485.2851 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 9.76 2170.6 - 55451.2 - - - 1.3494 - 1.019 0.044 - 100 1 2 0 0.0013 8 0 0 0 4.97E+06 3.24E+06 - - - -0.5777 0.961 230117_WJC_METTL3_WT_vs_EV_F03.07975.07975.2 17 12-May R.IPPVAVR[166.11].L "sp|Q14839|CHD4_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A0G2JM70|A0A0G2JM70_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|V9GYG6|V9GYG6_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 760.4835 0.001 18575 7975 2 760.484284 381.249 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 2170.9 - 320713 - - - 1.0585 - 0.997 0.11 - 92.8 4 2 0 0.0008 7 0 0 0 0.00E+00 1.43E+08 - - - -0.4253 0.9954 230117_WJC_METTL3_WT_vs_EV_F03.08124.08124.2 0.0322 12-Jul R.FC[160.03]ALEEK.C "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 895.411 0.29 18589 8124 2 895.410251 448.7128 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2196.2 - 164942 - - - -0.7851 - 1.258 0.268 - 151.5 1 2 0 -0.0007 7 0 0 0 7.72E+06 2.63E+07 - - - 1.7475 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.08216.08216.2 0.293 14-Jun K.C[160.03]GEALGLK.Q "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 846.4269 0.55 18597 8216 2 846.428079 424.2207 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.99 2212.1 - 113629 - - - 1.3468 - 1.46 0.174 - 154.7 1 2 0 0.0011 8 0 0 0 1.22E+07 2.21E+07 - - - 1.4672 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.08227.08227.2 0.0184 12-Aug K.VLAAVYK[136.11].A "sp|P05062|ALDOB_HUMAN,sp|P04075|ALDOA_HUMAN,sp|P09972|ALDOC_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|A8MVZ9|A8MVZ9_HUMAN,tr|A0A3B3IS80|A0A3B3IS80_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|A0A087WXX2|A0A087WXX2_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 10 770.4782 1.9 18599 8227 2 770.478917 386.2464 Fructose-bisphosphate aldolase B OS=Homo sapiens OX=9606 GN=ALDOB PE=1 SV=2 8.56 2213.8 - 741489 - - - 0.9617 - 1.531 0.204 - 258.7 1 2 0 0.0007 7 0 0 0 1.67E+08 8.76E+07 - - - 1.8971 0.8735 230117_WJC_METTL3_WT_vs_EV_F03.08228.08228.2 0.111 16-Aug R.PSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 969.5243 0.75 18600 8228 2 969.524934 485.7694 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.43 2213.9 - 181048 - - - 0.6085 - 1.567 0.213 - 199.2 1 1 0 0.0006 9 0 0 0 8.51E+06 1.13E+07 - - - 1.9135 0.9956 230117_WJC_METTL3_WT_vs_EV_F03.08257.08257.2 0.155 12-Jun R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 595.05 18603 8257 2 808.432937 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2218.9 - 1.18E+06 - - - -0.1645 - 1.296 0.216 - 60.6 1 2 0 -0.0001 7 0 0 0 1.16E+08 1.94E+05 - - - 1.4579 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.08265.08265.2 0.000355 18-Oct K.LLNTVEETTK[136.11].D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1154.6274 0.14 18605 8265 2 1154.630299 578.321 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2220.1 - 294056 - - - 2.4943 - 2.168 0.4 - 290.4 1 2 0 0.0029 10 0 0 0 2.96E+06 2.10E+07 - - - 4.1544 0.997 230117_WJC_METTL3_WT_vs_EV_F03.08271.08271.2 0.0554 18-Oct K.LLNTVEETTK.D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1146.6132 0.14 18606 8271 2 1146.617296 574.3139 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2221.1 - 599814 - - - 3.5557 - 1.529 0.272 - 257.3 1 2 0 0.0041 10 0 0 0 2.89E+06 2.10E+07 - - - 2.2339 0.986 230117_WJC_METTL3_WT_vs_EV_F03.08275.08275.2 4.21 16-May R.VPPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 942.5651 1.05 18608 8275 2 942.565905 472.2898 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2221.6 - 241288 - - - 0.8678 - 1.149 0.149 - 49.2 4 2 0 0.0008 9 0 0 0 2.40E+07 2.28E+07 - - - 0.2741 0.9772 230117_WJC_METTL3_WT_vs_EV_F03.08288.08288.2 4.75 12-Jun K.LVTDLTK.V "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 788.4644 5.68 18611 8288 2 788.464786 395.2395 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.84 2223.5 - 772703 - - - 0.5276 - 1.138 0.076 - 108.5 1 2 0 0.0004 7 0 0 0 2.59E+07 4.56E+06 - - - 0.0118 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.08296.08296.2 0.123 14-Jul R.ILSGVVTK.M "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 815.5117 0.87 18613 8296 2 815.511938 408.7631 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 2224.7 - 286945 - - - 0.3482 - 1.439 0.172 - 119.6 1 2 0 0.0003 8 0 0 0 3.34E+07 3.83E+07 - - - 1.409 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.08319.08319.2 0.223 14-Sep R.IVVAAVAR[166.11].A "sp|Q7Z2T5|TRM1L_HUMAN,tr|X6RK96|X6RK96_HUMAN" 2 807.5206 1.65 18618 8319 2 807.520984 404.7676 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 9.75 2228.5 - 609275 - - - 0.4842 - 1.684 0.236 - 220.3 1 2 0 0.0004 8 0 0 0 5.44E+07 3.29E+07 - - - 2.3558 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.08361.08361.2 0.0743 18-Sep R.ASAVSELSPR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1025.5381 0.85 18626 8361 2 1025.54046 513.7763 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2235 - 147445 - - - 2.3071 - 1.745 0.233 - 144.9 1 2 0 0.0024 10 0 0 0 1.04E+07 1.22E+07 - - - 2.3153 0.999 230117_WJC_METTL3_WT_vs_EV_F03.08387.08387.2 0.00373 18-Sep R.ASAVSELSPR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1015.5298 0.86 18629 8387 2 1015.531985 508.7722 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2239.4 - 121686 - - - 2.128 - 1.534 0.317 - 173.6 1 2 0 0.0022 10 0 0 0 1.04E+07 1.22E+07 - - - 2.576 0.9589 230117_WJC_METTL3_WT_vs_EV_F03.08422.08422.2 0.497 12-Jun R.LLPAEVK[136.11].A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 776.4887 1.24 18633 8422 2 776.487775 389.2516 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6 2245.2 - 1.77E+06 - - - -1.2441 - 1.199 0.136 - 110.6 6 2 0 -0.001 7 0 0 0 2.19E+08 1.76E+08 - - - 0.2726 0.9838 230117_WJC_METTL3_WT_vs_EV_F03.08464.08464.2 6.82 12-May K.SEITELR.R "sp|P13645|K1C10_HUMAN,sp|Q8TDM6|DLG5_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 3 846.4447 6.47 18636 8464 2 846.44532 424.2296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2252.4 - 203659 - - - 0.736 - 1.101 0.115 - 139 1 2 0 0.0006 7 0 0 0 1.04E+07 1.60E+06 - - - 0.1951 1 230117_WJC_METTL3_WT_vs_EV_F03.08480.08480.2 2.83E-07 20-Dec K.FAEALGSTEAK[136.11].A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1130.5699 0.34 18640 8480 2 1130.571512 566.2922 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2254.8 - 313008 - - - 1.4223 - 2.276 0.502 - 447.4 1 2 0 0.0016 11 0 0 0 4.45E+06 1.29E+07 - - - 4.9731 0.998 230117_WJC_METTL3_WT_vs_EV_F03.08583.08583.2 0.0923 16-Jul R.ILQDSLGGR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 967.5326 0.32 18657 8583 2 967.533908 484.7736 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2271.2 - 147854 - - - 1.3374 - 1.359 0.241 - 151.2 1 2 0 0.0013 9 0 0 0 5.79E+06 1.80E+07 - - - 1.7081 0.9732 230117_WJC_METTL3_WT_vs_EV_F03.08610.08610.2 2.96 16-Jun R.ILQDSLGGR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 957.5243 0.32 18661 8610 2 957.524322 479.7694 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2275.6 - 158722 - - - -0.023 - 1.247 0.071 - 86.8 2 2 0 0 9 0 0 0 5.79E+06 1.80E+07 - - - 0.0695 0.9457 230117_WJC_METTL3_WT_vs_EV_F03.08708.08708.2 7.09 12-Jul R.LLEQGIR.V "sp|P28340|DPOD1_HUMAN,sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 7 827.4865 1.61 18674 8708 2 827.486184 414.7505 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 6 2291.9 - 209166 - - - -0.3843 - 1.223 0.007 - 151.3 1 2 0 -0.0003 7 0 0 0 3.51E+07 2.19E+07 - - - -0.2695 0.9924 230117_WJC_METTL3_WT_vs_EV_F03.08771.08771.2 0.201 12-Jul K.NIQVVVR[166.11].C "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 836.5108 0.25 18685 8771 2 836.509101 419.2627 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 9.75 2301.5 - 1.16E+06 - - - -1.9797 - 1.351 0.269 - 222.8 1 2 0 -0.0017 7 0 0 0 2.05E+07 8.20E+07 - - - 1.9806 0.9931 230117_WJC_METTL3_WT_vs_EV_F03.08841.08841.2 0.0149 12-Jul R.AMIIAER[166.11].Q "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 812.4454 2.08 18691 8841 2 812.443554 407.23 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.05 2312.9 - 513040 - - - -2.2463 - 1.634 0.222 - 266.7 1 2 0 -0.0018 7 0 0 0 5.85E+07 2.81E+07 - - - 2.236 0.9902 230117_WJC_METTL3_WT_vs_EV_F03.08868.08868.2 0.158 12-Jul R.AMIIAER.Q "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 802.4371 1.91 18699 8868 2 802.437319 402.2258 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.05 2316.9 - 829626 - - - 0.2617 - 1.503 0.045 - 211.8 1 2 0 0.0002 7 0 0 0 5.37E+07 2.81E+07 - - - 0.6644 0.9456 230117_WJC_METTL3_WT_vs_EV_F03.08904.08904.2 4.03 12-Jul K.LIVDSVK.E sp|O60216|RAD21_HUMAN 1 772.4695 3.68 18705 8904 2 772.469911 387.242 Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2 5.84 2322.8 - 1.33E+06 - - - 0.5903 - 1.149 0.011 - 148.6 2 2 0 0.0005 7 0 0 0 6.06E+07 1.65E+07 - - - -0.5723 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.08909.08909.2 0.0852 16-Sep R.NIVEAAAVR[166.11].D "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 951.5377 0.94 18706 8909 2 951.538457 476.7761 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 6 2323.6 - 1.07E+06 - - - 0.7956 - 1.079 0.3 - 231.1 1 2 0 0.0008 9 0 0 0 1.73E+07 1.85E+07 - - - 1.4765 0.9897 230117_WJC_METTL3_WT_vs_EV_F03.08918.08918.2 1.23 14-Jun K.LVIEEAER.S sp|P50991|TCPD_HUMAN 1 957.5131 14.25 18707 8918 2 957.51363 479.7638 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.25 2325.1 - 145978 - - - 0.542 - 1.128 0.155 - 127.1 1 2 0 0.0005 8 0 0 0 8.99E+06 6.31E+05 - - - 0.5489 0.986 230117_WJC_METTL3_WT_vs_EV_F03.08925.08925.2 2.59 12-Jun K.LIETVVK[136.11].Q "sp|Q8TAG9|EXOC6_HUMAN,tr|E7EW84|E7EW84_HUMAN" 2 808.515 1.82 18708 8925 2 808.51615 405.2648 Exocyst complex component 6 OS=Homo sapiens OX=9606 GN=EXOC6 PE=1 SV=3 6 2326.2 - 137036 - - - 1.478 - 1.195 0.086 - 73.9 1 2 0 0.0012 7 0 0 0 1.50E+07 8.24E+06 - - - 0.2403 0.971 230117_WJC_METTL3_WT_vs_EV_F03.08940.08940.2 0.544 12-Aug R.HLQLAIR[166.11].N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 859.5267 0.82 18710 8940 2 859.526454 430.7706 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2328.7 - 345906 - - - -0.3339 - 1.408 0.001 - 266.4 1 2 0 -0.0003 7 0 0 0 9.59E+07 1.17E+08 - - - 0.1325 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.08962.08962.2 0.0985 12-Aug K.IIDAALR[166.11].A "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 780.4733 2.25 18711 8962 2 780.473544 391.2439 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2332.5 - 969042 - - - 0.3024 - 1.42 0.223 - 174.3 1 2 0 0.0002 7 0 0 0 2.22E+09 9.85E+08 - - - 1.7991 0.9862 230117_WJC_METTL3_WT_vs_EV_F03.08966.08966.2 0.311 12-Aug K.IIDAALR.A "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 770.465 2.25 18713 8966 2 770.464166 386.2398 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2333 - 2.13E+06 - - - -1.1318 - 1.342 0.142 - 215 1 2 0 -0.0009 7 0 0 0 2.22E+09 9.86E+08 - - - 1.0216 0.9297 230117_WJC_METTL3_WT_vs_EV_F03.09075.09075.3 0.341 Oct-36 R.LKYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1233.6717 1.19 18729 9075 3 1233.669138 412.2312 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2350.2 - 493130 - - - -2.1067 - 1.975 0.372 - 174.2 1 2 1 -0.0026 10 0 0 0 3.69E+07 3.10E+07 - - - 4.6743 0.9913 230117_WJC_METTL3_WT_vs_EV_F03.09124.09124.2 0.868 12-Jun R.LVGEIVR[166.11].R "sp|Q13232|NDK3_HUMAN,sp|Q15021|CND1_HUMAN,sp|Q3MIP1|IPIL2_HUMAN,tr|H3BRA8|H3BRA8_HUMAN,tr|H3BMQ7|H3BMQ7_HUMAN,tr|H3BPD9|H3BPD9_HUMAN,tr|E7EN77|E7EN77_HUMAN" 7 794.489 1.62 18735 9124 2 794.489119 398.2518 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6 2358 - 658042 - - - 0.2014 - 1.51 0.076 - 127.2 2 2 0 0.0002 7 0 0 0 6.23E+08 3.86E+08 - - - 0.7736 0.9866 230117_WJC_METTL3_WT_vs_EV_F03.09131.09131.2 8.35 12-Aug R.LVGEIVR.R "sp|Q13232|NDK3_HUMAN,sp|Q15021|CND1_HUMAN,sp|Q3MIP1|IPIL2_HUMAN,tr|H3BRA8|H3BRA8_HUMAN,tr|H3BMQ7|H3BMQ7_HUMAN,tr|H3BPD9|H3BPD9_HUMAN,tr|E7EN77|E7EN77_HUMAN" 7 784.4807 1.09 18737 9131 2 784.480426 393.2476 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6 2359 - 1.18E+06 - - - -0.3353 - 1.394 0.078 - 241.8 1 2 0 -0.0003 7 0 0 0 4.06E+08 3.73E+08 - - - 0.6695 0.862 230117_WJC_METTL3_WT_vs_EV_F03.09145.09145.2 4.62 12-May K.YGLAAFR[166.11].A sp|P41220|RGS2_HUMAN 1 806.4314 0.86 18742 9145 2 806.431407 404.223 Regulator of G-protein signaling 2 OS=Homo sapiens OX=9606 GN=RGS2 PE=1 SV=1 8.75 2361.1 - 419596 - - - -0.0459 - 1.019 0.012 - 106.8 3 2 0 0 7 0 0 0 1.77E+07 2.05E+07 - - - -1.0239 0.9887 230117_WJC_METTL3_WT_vs_EV_F03.09172.09172.2 0.366 12-Jul K.VC[160.03]ADLIR.G "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 3 845.4429 1.8 18744 9172 2 845.442449 423.7287 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.8 2365.8 - 181012 - - - -0.5607 - 1.301 0.139 - 178.2 1 2 0 -0.0005 7 0 0 0 1.01E+07 5.62E+06 - - - 0.9013 0.8742 230117_WJC_METTL3_WT_vs_EV_F03.09205.09205.2 0.0508 12-Jun G.PSTVEER[166.11].V "sp|Q18PE1|DOK7_HUMAN,tr|A0A2R8Y701|A0A2R8Y701_HUMAN" 2 826.406 1.96 18748 9205 2 826.406608 414.2103 Protein Dok-7 OS=Homo sapiens OX=9606 GN=DOK7 PE=1 SV=1 4.53 2371.2 - 158842 - - - 0.7151 - 1.306 0.271 - 122 1 1 0 0.0006 7 0 0 0 1.78E+07 9.09E+06 - - - 1.8883 0.9404 230117_WJC_METTL3_WT_vs_EV_F03.09249.09249.2 0.403 14-May R.GLDVEDVK.F "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 6 873.4444 0.95 18753 9249 2 873.445139 437.7295 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 2378.4 - 146532 - - - 0.8884 - 1.004 0.054 - 56.5 2 2 0 0.0008 8 0 0 0 1.15E+07 1.20E+07 - - - -0.6828 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.09298.09298.2 0.162 14-Aug K.VIPELNGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 868.5018 2.91 18758 9298 2 868.502951 435.2582 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2386.6 - 1.18E+06 - - - 1.3045 - 1.248 0.323 - 214.1 1 2 0 0.0011 8 0 0 0 9.02E+07 3.10E+07 - - - 2.0945 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.09304.09304.2 7.48E-05 16-Sep R.QTVAVGVIK.N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 913.5597 4.23 18760 9304 2 913.560815 457.7871 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2387.5 - 1.11E+06 - - - 1.2566 - 1.807 0.449 - 346.1 1 2 0 0.0011 9 0 0 0 6.14E+07 1.45E+07 - - - 4.0687 0.9575 230117_WJC_METTL3_WT_vs_EV_F03.09342.09342.2 3.75 12-Jun K.VVPLYGR[166.11].G "sp|Q99942|RNF5_HUMAN,tr|A0A140TA09|A0A140TA09_HUMAN" 2 812.4784 2.06 18770 9342 2 812.479594 407.2465 E3 ubiquitin-protein ligase RNF5 OS=Homo sapiens OX=9606 GN=RNF5 PE=1 SV=1 8.72 2393.2 - 391785 - - - 1.477 - 1.064 0.037 - 155.9 1 2 0 0.0012 7 0 0 0 6.62E+07 3.21E+07 - - - -0.4895 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.09350.09350.2 0.103 14-Jul R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 1.26 18773 9350 2 898.525379 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 2394.2 - 496686 - - - 1.9621 - 1.352 0.314 - 142 1 2 0 0.0018 8 0 0 0 5.70E+07 4.53E+07 - - - 2.2692 0.994 230117_WJC_METTL3_WT_vs_EV_F03.09360.09360.2 0.0406 12-Jun K.VVPLYGR.G "sp|Q99942|RNF5_HUMAN,tr|A0A140TA09|A0A140TA09_HUMAN" 2 802.4701 2.59 18776 9360 2 802.472223 402.2423 E3 ubiquitin-protein ligase RNF5 OS=Homo sapiens OX=9606 GN=RNF5 PE=1 SV=1 8.72 2395.8 - 866133 - - - 2.6157 - 1.153 0.222 - 224.3 1 2 0 0.0021 7 0 0 0 8.51E+07 3.29E+07 - - - 1.1311 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.09375.09375.2 0.183 14-Oct R.LVGDVIQR[166.11].F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 908.5319 1.24 18777 9375 2 908.533003 455.2732 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 2398.4 - 758101 - - - 1.2295 - 1.369 0.219 - 311 1 2 0 0.0011 8 0 0 0 5.44E+07 4.38E+07 - - - 1.6054 0.959 230117_WJC_METTL3_WT_vs_EV_F03.09439.09439.2 0.00102 14-Sep R.YPDGIISK.P sp|Q86U44|MTA70_HUMAN 1 891.4702 168.45 18789 9439 2 891.472177 446.7424 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2408.8 - 1.57E+06 - - - 2.2368 - 1.421 0.447 - 234 1 1 0 0.002 8 0 0 0 3.70E+08 2.20E+06 - - - 3.4016 0.9878 230117_WJC_METTL3_WT_vs_EV_F03.09451.09451.2 5.06 12-Aug R.IAPDVLR[166.11].K "sp|Q13367|AP3B2_HUMAN,sp|O00203|AP3B1_HUMAN,tr|A0A590UK64|A0A590UK64_HUMAN,tr|A0A590UK04|A0A590UK04_HUMAN,tr|A0A5F9UJV3|A0A5F9UJV3_HUMAN,tr|A0A590UJU0|A0A590UJU0_HUMAN,tr|A0A590UKD3|A0A590UKD3_HUMAN,tr|A0A590UJE5|A0A590UJE5_HUMAN,tr|A0A590UJU7|A0A590UJU7_HUMAN,tr|A0A2R8Y2A8|A0A2R8Y2A8_HUMAN,tr|A0A590UJ60|A0A590UJ60_HUMAN,tr|A0A590UKC4|A0A590UKC4_HUMAN" 12 792.4733 1.87 18792 9451 2 792.474195 397.2439 AP-3 complex subunit beta-2 OS=Homo sapiens OX=9606 GN=AP3B2 PE=1 SV=2 5.84 2410.7 - 1.31E+06 - - - 1.1193 - 1.131 0.123 - 137.4 1 2 0 0.0009 7 0 0 0 2.18E+07 1.17E+07 - - - 0.3393 0.9742 230117_WJC_METTL3_WT_vs_EV_F03.09495.09495.2 1.08 12-May R.IVTTYIR[166.11].E "sp|P50570|DYN2_HUMAN,tr|K7EMQ3|K7EMQ3_HUMAN" 2 874.5152 1.45 18800 9495 2 874.515321 438.2649 Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2 8.75 2417.6 - 456388 - - - 0.1692 - 0.941 0.16 - 72 1 2 0 0.0001 7 0 0 0 2.23E+07 1.53E+07 - - - 0.03 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.09532.09532.2 0.00433 18-Aug R.GYSFTTTAER.E "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1131.5197 1.36 18807 9532 2 1131.519789 566.7671 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 2423.3 - 133352 - - - 0.1202 - 1.595 0.385 - 235.7 1 2 0 0.0001 10 0 0 0 6.01E+06 4.44E+06 - - - 3.1878 0.9961 230117_WJC_METTL3_WT_vs_EV_F03.09536.09536.2 0.0214 18-Jun R.GYSFTTTAER[166.11].E "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1141.5279 1.36 18809 9536 2 1141.528304 571.7712 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 2423.7 - 101715 - - - 0.3338 - 0.993 0.314 - 82.3 1 2 0 0.0004 10 0 0 0 6.01E+06 4.44E+06 - - - 1.3405 0.999 230117_WJC_METTL3_WT_vs_EV_F03.09538.09538.2 0.647 14-Aug R.LVTTGVLK.Q sp|P07305|H10_HUMAN 1 829.5273 1.05 18810 9538 2 829.528005 415.7709 Histone H1.0 OS=Homo sapiens OX=9606 GN=H1-0 PE=1 SV=3 8.75 2424 - 602555 - - - 0.8451 - 1.717 0.241 - 221.4 1 2 0 0.0007 8 0 0 0 2.36E+07 2.26E+07 - - - 2.4512 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.09549.09549.2 0.00705 18-Jun K.FADLSEAANR.N "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1092.52 1.44 18813 9549 2 1092.521581 547.2673 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 2425.6 - 144728 - - - 1.459 - 1.538 0.338 - 102.8 1 2 0 0.0016 10 0 0 0 2.34E+07 1.63E+07 - - - 2.7386 0.9243 230117_WJC_METTL3_WT_vs_EV_F03.09587.09587.2 2.21 12-May K.LLPYAER[166.11].L "sp|Q14997|PSME4_HUMAN,tr|F8WBH5|F8WBH5_HUMAN" 2 870.4839 1.59 18821 9587 2 870.485908 436.2492 Proteasome activator complex subunit 4 OS=Homo sapiens OX=9606 GN=PSME4 PE=1 SV=2 6 2431.5 - 99997.8 - - - 2.3378 - 0.912 0.072 - 78.5 1 2 0 0.002 7 0 0 0 9.54E+06 6.01E+06 - - - -0.7197 0.9957 230117_WJC_METTL3_WT_vs_EV_F03.09596.09596.2 0.0173 16-Jun R.QAVDVSPLR[166.11].R "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 993.5483 0.82 18823 9596 2 993.55149 497.7814 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 5.84 2432.9 - 101799 - - - 3.2469 - 1.305 0.258 - 80.7 1 2 0 0.0032 9 0 0 0 3.51E+06 4.27E+06 - - - 1.7157 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.09644.09644.2 4.63 14-Jul R.LLTGPVVR.G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 853.5385 2.52 18834 9644 2 853.539116 427.7765 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2440.1 - 316825 - - - 0.6772 - 1.463 0.184 - 127.8 1 2 0 0.0006 8 0 0 0 3.67E+07 1.45E+07 - - - 1.5474 0.992 230117_WJC_METTL3_WT_vs_EV_F03.09652.09652.2 4.53 12-May K.LEPVPLK.G "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN" 2 794.4902 2.76 18838 9652 2 794.490365 398.2524 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6 2441.2 - 813150 - - - 0.219 - 1.187 0.169 - 109.5 1 2 0 0.0002 7 0 0 0 6.00E+07 2.17E+07 - - - 0.8324 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.09657.09657.2 0.0645 14-Aug K.ALVAYYQK[136.11].Y "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 962.5317 3.29 18839 9657 2 962.533965 482.2731 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.54 2442 - 181928 - - - 2.3864 - 1.641 0.311 - 189 1 2 0 0.0023 8 0 0 0 2.62E+07 7.96E+06 - - - 2.8311 0.9853 230117_WJC_METTL3_WT_vs_EV_F03.09689.09689.2 1.29 12-Jun R.ILVDVEK.V sp|P11216|PYGB_HUMAN 1 814.48 0.31 18846 9689 2 814.480853 408.2473 "Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB PE=1 SV=5" 4.37 2447 - 862125 - - - 1.0227 - 1.254 0.081 - 110 2 2 0 0.0008 7 0 0 0 1.26E+07 4.12E+07 - - - 0.2217 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.09699.09699.3 7.38E-05 16/40 R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 1.12 18848 9699 3 1240.608989 414.5431 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2448.5 - 259573 - - - 1.1438 - 2.226 0.441 - 317.1 1 2 0 0.0014 11 0 0 0 2.14E+07 1.91E+07 - - - 5.7296 0.9924 230117_WJC_METTL3_WT_vs_EV_F03.09732.09732.2 0.123 12-Aug R.VLSSLVR.D sp|Q969H6|POP5_HUMAN 1 772.4807 1.71 18854 9732 2 772.482001 387.2476 Ribonuclease P\MRP protein subunit POP5 OS=Homo sapiens OX=9606 GN=POP5 PE=1 SV=1 9.72 2453.8 - 674613 - - - 1.6984 - 1.648 0.009 - 277.3 1 2 0 0.0013 7 0 0 0 4.33E+07 2.54E+07 - - - 0.69 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.09748.09748.2 0.0125 16-Jul K.IVVVTAGVR[166.11].Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 922.5839 0.82 18857 9748 2 922.584428 462.2992 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2456.4 - 545210 - - - 0.5485 - 1.513 0.258 - 129.1 1 2 0 0.0005 9 0 0 0 1.34E+08 1.63E+08 - - - 2.1444 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.09761.09761.2 0.00344 16-Aug K.IVVVTAGVR.Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 912.5757 0.81 18860 9761 2 912.576491 457.2951 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2458.5 - 1.10E+06 - - - 0.9194 - 1.706 0.362 - 223.9 1 2 0 0.0008 9 0 0 0 1.32E+08 1.63E+08 - - - 3.2598 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.09762.09762.2 0.00199 22-Sep R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 999 18861 9762 2 1380.640756 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2458.6 - 120545 - - - -0.0971 - 1.858 0.429 - 183.4 1 2 0 -0.0001 12 0 0 0 6.42E+06 0.00E+00 - - - 3.8396 0.9933 230117_WJC_METTL3_WT_vs_EV_F03.09774.09774.2 0.324 12-Jul K.LEATMLR[166.11].L "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 842.4559 8.62 18867 9774 2 842.456721 422.2352 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6 2460.1 - 316571 - - - 0.9223 - 1.372 0.101 - 130.2 1 2 0 0.0008 7 0 0 0 1.81E+08 2.10E+07 - - - 0.7889 0.9934 230117_WJC_METTL3_WT_vs_EV_F03.09783.09783.2 0.314 12-Jul K.LEATMLR.L "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 832.4477 1.19 18870 9783 2 832.447599 417.2311 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6 2461.4 - 446794 - - - -0.0901 - 1.467 0.114 - 174.2 1 2 0 -0.0001 7 0 0 0 1.96E+07 1.65E+07 - - - 1.0972 0.8621 230117_WJC_METTL3_WT_vs_EV_F03.09800.09800.2 0.446 12-Jun K.K[136.11]EAAPEK[136.11].K sp|P12036|NFH_HUMAN 1 787.4411 0 18877 9800 2 787.436516 394.7278 Neurofilament heavy polypeptide OS=Homo sapiens OX=9606 GN=NEFH PE=1 SV=4 6.14 2463.6 - 613671 - - - -5.782 - 1.283 0.213 - 165.9 1 2 0 -0.0046 7 0 0 0 1.06E+07 2.14E+09 - - - 1.4024 0.8957 230117_WJC_METTL3_WT_vs_EV_F03.09808.09808.2 0.181 12-Jun N.VDEFVK[136.11]R.L sp|Q9NVH2|INT7_HUMAN 1 899.4956 - 18880 9808 2 899.496279 450.7551 Integrator complex subunit 7 OS=Homo sapiens OX=9606 GN=INTS7 PE=1 SV=1 6.04 2464.7 - 636630 - - - 0.736 - 1.31 0.296 - 93.6 1 1 0 0.0007 7 0 0 0 - - - - - 2.0826 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.09813.09813.2 0.00407 18-Oct K.IGAVEEELNR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1138.5858 0.9 18882 9813 2 1138.587917 570.3002 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.25 2465.4 - 206951 - - - 1.8839 - 2.057 0.343 - 334.2 1 2 0 0.0021 10 0 0 0 5.42E+06 6.00E+06 - - - 3.5869 0.8475 230117_WJC_METTL3_WT_vs_EV_F03.09820.09820.2 1.52 12-Jun R.IPGIYGR.L "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 774.4388 1.13 18884 9820 2 774.435779 388.2267 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.75 2466.4 - 208813 - - - -3.9319 - 1.208 0.11 - 89.6 1 2 0 -0.003 7 0 0 0 1.32E+08 1.17E+08 - - - 0.4513 0.998 230117_WJC_METTL3_WT_vs_EV_F03.09849.09849.2 0.0264 18-Aug K.MLVSGAGDIK.L "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 989.5216 17.5 18889 9849 2 989.521793 495.7681 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.59 2471 - 198734 - - - 0.2284 - 1.291 0.297 - 170.4 1 2 0 0.0002 10 0 0 0 1.29E+07 7.37E+05 - - - 1.9475 0.997 230117_WJC_METTL3_WT_vs_EV_F03.09886.09886.2 0.129 12-Jul R.MIVGTLK.G "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 760.4517 2.65 18890 9886 2 760.451992 381.2331 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 8.5 2477.5 - 1.10E+06 - - - 0.3879 - 1.259 0.239 - 185.9 1 2 0 0.0003 7 0 0 0 3.38E+08 1.28E+08 - - - 1.5359 0.9763 230117_WJC_METTL3_WT_vs_EV_F03.09890.09890.2 1.65 12-Aug R.MIVGTLK[136.11].G "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 768.4659 2.64 18892 9890 2 768.465626 385.2402 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 8.5 2478 - 871445 - - - -0.3527 - 1.049 0.147 - 185.4 1 2 0 -0.0003 7 0 0 0 3.38E+08 1.28E+08 - - - 0.2782 0.8802 230117_WJC_METTL3_WT_vs_EV_F03.09903.09903.2 0.0251 16-Aug L.LADSMVALR.T "sp|Q9GZW8|MS4A7_HUMAN,tr|E9PN40|E9PN40_HUMAN,tr|E9PIV6|E9PIV6_HUMAN" 3 974.5219 1.24 18895 9903 2 974.523631 488.2682 Membrane-spanning 4-domains subfamily A member 7 OS=Homo sapiens OX=9606 GN=MS4A7 PE=1 SV=1 5.84 2479.9 - 390758 - - - 1.7752 - 1.521 0.223 - 152.2 1 1 0 0.0017 9 0 0 0 6.09E+07 4.93E+07 - - - 1.9008 0.9916 230117_WJC_METTL3_WT_vs_EV_F03.09906.09906.2 0.663 12-Jul R.ILLEAAR[166.11].L "sp|P49189|AL9A1_HUMAN,sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 3 794.489 2.11 18896 9906 2 794.488356 398.2518 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3 6 2480.4 - 497428 - - - -0.759 - 1.446 0.137 - 170 1 2 0 -0.0006 7 0 0 0 6.62E+07 3.13E+07 - - - 1.2213 0.9863 230117_WJC_METTL3_WT_vs_EV_F03.09921.09921.2 3.97 12-May R.ILLEAAR.L "sp|P49189|AL9A1_HUMAN,sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 3 784.4807 2.13 18899 9921 2 784.480877 393.2476 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3 6 2482.7 - 1.48E+06 - - - 0.2396 - 1.249 0.136 - 66.4 5 2 0 0.0002 7 0 0 0 6.72E+07 3.16E+07 - - - 0.4377 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.09980.09980.2 0.0461 16-Aug R.SLVNLGGSK.S sp|P04264|K2C1_HUMAN 1 873.492 76.38 18907 9980 2 873.492299 437.7533 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.47 2492.4 - 240989 - - - 0.3629 - 1.448 0.411 - 226.9 1 2 0 0.0003 9 0 0 0 4.65E+07 6.09E+05 - - - 3.1475 0.9816 230117_WJC_METTL3_WT_vs_EV_F03.09988.09988.2 6.14 12-Jul K.LGPEAFR[166.11].F sp|P33908|MA1A1_HUMAN 1 798.4264 0.39 18908 9988 2 798.426228 400.2205 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 6 2493.7 - 389599 - - - -0.1628 - 1.221 0.095 - 169.8 1 2 0 -0.0001 7 0 0 0 4.78E+07 1.22E+08 - - - 0.3753 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.10001.10001.2 0.178 14-Jul R.VMGLVPAK.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 813.4782 1.64 18913 10001 2 813.478667 407.7464 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.72 2495.6 - 128034 - - - 0.5175 - 1.256 0.259 - 138.3 1 2 0 0.0004 8 0 0 0 3.80E+07 2.31E+07 - - - 1.6413 1 230117_WJC_METTL3_WT_vs_EV_F03.10004.10004.2 1.10E-06 22-Nov R.AQVQEFC[160.03]DYGTK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1444.6293 7.37 18914 10004 2 1444.630563 723.3219 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2496 - 125606 - - - 0.8881 - 2.037 0.617 - 313.2 1 2 0 0.0013 12 0 0 0 2.45E+07 3.32E+06 - - - 5.4698 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.10021.10021.2 0.00179 22-Jun R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 7.37 18918 10021 2 1452.644104 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2498.5 - 70275.3 - - - 0.4296 - 1.57 0.414 - 95 1 2 0 0.0006 12 0 0 0 2.45E+07 3.32E+06 - - - 3.2855 0.9469 230117_WJC_METTL3_WT_vs_EV_F03.10039.10039.2 0.192 12-Jun R.LMDVMAK.E sp|Q12874|SF3A3_HUMAN 1 806.403 3.07 18921 10039 2 806.399375 404.2088 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2501.4 - 170385 - - - -4.535 - 1.212 0.268 - 106.5 1 2 0 -0.0037 7 0 0 0 1.07E+08 3.50E+07 - - - 1.6285 0.9836 230117_WJC_METTL3_WT_vs_EV_F03.10042.10042.2 2.48 16-May R.GPLVNASLR[166.11].A "sp|O14744|ANM5_HUMAN,tr|H0YJ77|H0YJ77_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 3 935.5428 0.48 18922 10042 2 935.542532 468.7787 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 9.75 2501.9 - 43342.9 - - - -0.2704 - 1.176 0.163 - 67.1 3 2 0 -0.0003 9 0 0 0 2.57E+06 5.33E+06 - - - 0.5007 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.10058.10058.2 0.0122 14-Aug R.VMGLVPAK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 821.4924 1.66 18924 10058 2 821.493324 411.7535 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.72 2504.6 - 269073 - - - 1.0688 - 1.245 0.29 - 172.6 1 2 0 0.0009 8 0 0 0 3.79E+07 2.29E+07 - - - 1.8436 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.10062.10062.2 0.0208 12-Jun R.LMDVMAK[136.11].E sp|Q12874|SF3A3_HUMAN 1 814.4172 3.08 18925 10062 2 814.417747 408.2159 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2505.1 - 498903 - - - 0.6324 - 1.277 0.374 - 90.6 1 2 0 0.0005 7 0 0 0 1.08E+08 3.51E+07 - - - 2.578 0.941 230117_WJC_METTL3_WT_vs_EV_F03.10093.10093.2 0.321 12-Jun -.MAAPILR.S sp|Q9Y2Z4|SYYM_HUMAN 1 770.4473 4.1 18929 10093 2 770.446345 386.2309 "Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2" 9.5 2510.5 - 2.07E+06 - - - -1.2136 - 1.252 0.053 - 123.8 2 2 0 -0.0009 7 0 0 0 1.29E+08 3.15E+07 - - - 0.0098 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.10155.10155.2 1.03 16-Aug K.VELQELNDR.F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1114.5619 3.77 18939 10155 2 1114.565106 558.2882 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.14 2520.9 - 258325 - - - 2.9195 - 1.741 0.239 - 330 1 2 0 0.0033 9 0 0 0 2.37E+07 6.28E+06 - - - 2.4093 0.9347 230117_WJC_METTL3_WT_vs_EV_F03.10173.10173.2 8.81 14-Jun K.DLPLVSIK.S "sp|Q5JTW2|CEP78_HUMAN,tr|A0A2R8YFB0|A0A2R8YFB0_HUMAN,tr|A0A2R8YCP0|A0A2R8YCP0_HUMAN,tr|A0A2R8Y5W6|A0A2R8Y5W6_HUMAN,tr|A8MST6|A8MST6_HUMAN,tr|A0A2R8Y4C1|A0A2R8Y4C1_HUMAN,tr|A0A2R8Y7U5|A0A2R8Y7U5_HUMAN,tr|A0A2R8Y7A4|A0A2R8Y7A4_HUMAN,tr|A0A2U3TZI9|A0A2U3TZI9_HUMAN,tr|A0A2R8Y589|A0A2R8Y589_HUMAN,tr|A0A2R8Y432|A0A2R8Y432_HUMAN,tr|A0A2R8Y7M8|A0A2R8Y7M8_HUMAN" 12 883.5379 2.1 18942 10173 2 883.538293 442.7762 Centrosomal protein of 78 kDa OS=Homo sapiens OX=9606 GN=CEP78 PE=1 SV=1 5.84 2523.7 - 1.29E+06 - - - 0.4799 - 0.984 0.046 - 95.7 1 2 0 0.0004 8 0 0 0 8.38E+07 4.00E+07 - - - -0.668 0.9961 230117_WJC_METTL3_WT_vs_EV_F03.10174.10174.2 1.79 12-Jul R.VLYSLAK[136.11].K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 800.4887 1.35 18943 10174 2 800.4889 401.2516 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.56 2523.8 - 447799 - - - 0.1986 - 1.591 0.12 - 179.5 1 2 0 0.0002 7 0 0 0 6.00E+07 4.45E+07 - - - 1.3986 0.9778 230117_WJC_METTL3_WT_vs_EV_F03.10177.10177.2 1.7 12-Jun R.VLYSLAK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 792.4745 1.4 18944 10177 2 792.473451 397.2445 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.56 2524.2 - 646607 - - - -1.3754 - 1.366 0.101 - 120.8 1 2 0 -0.0011 7 0 0 0 6.22E+07 4.45E+07 - - - 0.7749 0.9814 230117_WJC_METTL3_WT_vs_EV_F03.10216.10216.2 5.75 12-Jul R.LYTVVPR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 846.4963 1.67 18950 10216 2 846.496549 424.2554 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 2530.5 - 1.64E+06 - - - 0.2481 - 1.186 0.087 - 162.6 1 2 0 0.0002 7 0 0 0 1.57E+08 9.42E+07 - - - 0.224 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.10249.10249.2 0.224 14-Aug K.IPAMTIAK.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.4888 2.16 18958 10249 2 843.488949 422.7517 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2535.4 - 8.71E+06 - - - 0.1648 - 1.278 0.257 - 165 1 2 0 0.0001 8 0 0 0 1.82E+09 8.45E+08 - - - 1.679 0.9921 230117_WJC_METTL3_WT_vs_EV_F03.10255.10255.2 0.506 12-Jul R.VAPVLIR[166.11].E "sp|P30419|NMT1_HUMAN,sp|O60551|NMT2_HUMAN,tr|A0A7I2V3X4|A0A7I2V3X4_HUMAN,tr|A0A7I2V539|A0A7I2V539_HUMAN,tr|Q5VUC6|Q5VUC6_HUMAN,tr|A0A7I2V3U5|A0A7I2V3U5_HUMAN" 6 776.5148 0.82 18962 10255 2 776.514366 389.2647 Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2 9.72 2536.1 - 473895 - - - -0.5319 - 1.236 0.196 - 188.8 1 2 0 -0.0004 7 0 0 0 3.03E+07 3.71E+07 - - - 1.1599 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.10271.10271.2 0.000548 16-Jul R.VLPVYGGPK.G "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 928.5382 1.58 18967 10271 2 928.538322 465.2764 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 8.56 2538.3 - 253457 - - - 0.1282 - 1.457 0.433 - 134.5 1 2 0 0.0001 9 0 0 0 2.00E+07 1.27E+07 - - - 3.328 0.9881 230117_WJC_METTL3_WT_vs_EV_F03.10286.10286.2 1.31 12-Jun R.VAPVLIR.E "sp|P30419|NMT1_HUMAN,sp|O60551|NMT2_HUMAN,tr|A0A7I2V3X4|A0A7I2V3X4_HUMAN,tr|A0A7I2V539|A0A7I2V539_HUMAN,tr|Q5VUC6|Q5VUC6_HUMAN,tr|A0A7I2V3U5|A0A7I2V3U5_HUMAN" 6 766.5065 0.81 18970 10286 2 766.505815 384.2605 Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2 9.72 2540.6 - 623047 - - - -0.9054 - 1.155 0.207 - 200.6 1 2 0 -0.0007 7 0 0 0 3.02E+07 3.71E+07 - - - 1.0263 0.9934 230117_WJC_METTL3_WT_vs_EV_F03.10310.10310.2 0.278 14-Sep R.LLTGPVVR[166.11].G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 863.5468 1.99 18978 10310 2 863.545339 432.7807 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2543.8 - 2.90E+06 - - - -1.7011 - 1.723 0.172 - 243 1 2 0 -0.0015 8 0 0 0 2.88E+08 1.44E+08 - - - 1.9518 0.9235 230117_WJC_METTL3_WT_vs_EV_F03.10319.10319.2 1.55 14-Jun R.LLTGPVVR.G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 853.5385 2 18979 10319 2 853.536363 427.7765 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2545.3 - 6.12E+06 - - - -2.5482 - 1.3 0.094 - 97.6 2 2 0 -0.0022 8 0 0 0 2.89E+08 1.44E+08 - - - 0.3914 0.9409 230117_WJC_METTL3_WT_vs_EV_F03.10430.10430.2 3.1 12-Jun K.GDVQTIR.W sp|Q702N8|XIRP1_HUMAN 1 787.4188 999 18982 10430 2 787.417346 394.7167 Xin actin-binding repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=XIRP1 PE=1 SV=1 5.84 2564.1 - 7.80E+06 - - - -1.8681 - 1.238 0.077 - 227.8 1 2 0 -0.0015 7 0 0 0 3.82E+08 0.00E+00 - - - 0.2857 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.10437.10437.2 0.000707 12-Aug R.LVDMMER.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 892.4147 1.17 18984 10437 2 892.412717 447.2146 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 2565.1 - 1.80E+06 - - - -2.1761 - 1.316 0.499 - 243.1 1 2 0 -0.0019 7 0 0 0 1.68E+08 1.44E+08 - - - 3.5961 0.9956 230117_WJC_METTL3_WT_vs_EV_F03.10453.10453.2 0.151 12-Jun R.LVDMMER[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 902.4229 1.17 18986 10453 2 902.422564 452.2187 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 2567.6 - 4.01E+06 - - - -0.4045 - 1.1 0.301 - 117.4 1 2 0 -0.0004 7 0 0 0 1.68E+08 1.44E+08 - - - 1.5661 0.9395 230117_WJC_METTL3_WT_vs_EV_F03.10474.10474.2 0.00849 14-Aug K.PSPLLVGR.E "sp|Q13283|G3BP1_HUMAN,sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2R0|A0A7I2V2R0_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RGJ4|D6RGJ4_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|D6R9A4|D6R9A4_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|E5RI46|E5RI46_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 25 837.5072 1.09 18988 10474 2 837.506829 419.7609 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 10.18 2571.1 - 1.84E+06 - - - -0.4884 - 1.725 0.383 - 261.6 1 1 0 -0.0004 8 0 0 0 1.10E+08 1.01E+08 - - - 3.5141 0.9633 230117_WJC_METTL3_WT_vs_EV_F03.10488.10488.2 0.308 14-Aug R.VVLLAEGR.L sp|O43865|SAHH2_HUMAN 1 855.5178 4.15 18989 10488 2 855.513774 428.7662 S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1 PE=1 SV=2 5.97 2573.4 - 1.00E+06 - - - -4.7083 - 1.34 0.292 - 208.8 1 2 0 -0.004 8 0 0 0 3.81E+07 9.18E+06 - - - 2.0791 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.10491.10491.2 0.0866 12-Aug K.FIGELGK.L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 762.4276 2.27 18990 10491 2 762.426931 382.2211 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2573.8 - 2.24E+06 - - - -0.8643 - 1.654 0.232 - 236.9 1 2 0 -0.0007 7 0 0 0 2.39E+08 1.06E+08 - - - 2.3488 0.9173 230117_WJC_METTL3_WT_vs_EV_F03.10498.10498.2 0.154 12-Jun K.FIGELGK[136.11].L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 770.4418 2.19 18991 10498 2 770.436923 386.2282 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2574.9 - 891704 - - - -6.3172 - 1.498 0.256 - 138.2 1 2 0 -0.0049 7 0 0 0 2.31E+08 1.05E+08 - - - 2.2108 0.9635 230117_WJC_METTL3_WT_vs_EV_F03.10514.10514.2 1.19 12-Jun K.AIFDSLR.E "sp|Q15327|ANKR1_HUMAN,sp|A6NEQ2|F181B_HUMAN" 2 820.4443 190.26 18992 10514 2 820.442193 411.2294 Ankyrin repeat domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKRD1 PE=1 SV=2 5.88 2577.5 - 847172 - - - -2.5718 - 1.295 0.149 - 105.3 1 2 0 -0.0021 7 0 0 0 1.15E+08 6.06E+05 - - - 0.96 0.9929 230117_WJC_METTL3_WT_vs_EV_F03.10535.10535.2 0.00323 14-Aug R.LGPLQVAR.V sp|P38117|ETFB_HUMAN 1 852.5181 3.47 18994 10535 2 852.515325 427.2663 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 9.75 2580.9 - 3.76E+06 - - - -3.2985 - 1.744 0.301 - 269.3 1 2 0 -0.0028 8 0 0 0 2.73E+08 7.86E+07 - - - 2.9407 0.9053 230117_WJC_METTL3_WT_vs_EV_F03.10561.10561.2 4.52 12-Apr R.LVNIVPK[136.11].K "sp|Q8NEY8|PPHLN_HUMAN,tr|F8VRK2|F8VRK2_HUMAN,tr|F8VWU8|F8VWU8_HUMAN,tr|F8VXV7|F8VXV7_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8VPY7|F8VPY7_HUMAN" 6 789.5204 0.88 19000 10561 2 789.519483 395.7675 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 8.75 2584.7 - 2.84E+06 - - - -1.1298 - 1.011 0.12 - 40.7 5 2 0 -0.0009 7 0 0 0 1.87E+08 2.12E+08 - - - -0.3505 0.9734 230117_WJC_METTL3_WT_vs_EV_F03.10570.10570.2 0.839 12-Jul K.LDIAAVR[166.11].A "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 766.4577 0.05 19003 10570 2 766.456483 384.2361 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 5.84 2585.9 - 1.21E+06 - - - -1.533 - 1.408 0.08 - 148.8 1 2 0 -0.0012 7 0 0 0 2.94E+06 5.96E+07 - - - 0.7157 0.98 230117_WJC_METTL3_WT_vs_EV_F03.10574.10574.2 0.53 12-Jun K.AIFAGYK.R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 768.417 0.79 19004 10574 2 768.41652 385.2158 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2586.4 - 1.80E+06 - - - -0.6585 - 1.156 0.139 - 125.9 1 2 0 -0.0005 7 0 0 0 2.42E+08 3.06E+08 - - - 0.5268 0.9949 230117_WJC_METTL3_WT_vs_EV_F03.10585.10585.2 0.569 12-Jul K.AIFAGYK[136.11].R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 776.4312 0.77 19006 10585 2 776.431137 389.2229 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2588.1 - 3.42E+06 - - - -0.1146 - 1.322 0.187 - 204.7 1 2 0 -0.0001 7 0 0 0 2.42E+08 3.14E+08 - - - 1.3066 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.10597.10597.2 0.0882 12-Aug R.FLAPYGR.Q "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 822.4388 0.28 19009 10597 2 822.439127 412.2267 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 8.75 2589.8 - 524166 - - - 0.3684 - 1.278 0.21 - 260.7 1 2 0 0.0003 7 0 0 0 6.24E+07 2.22E+08 - - - 1.3692 0.9962 230117_WJC_METTL3_WT_vs_EV_F03.10612.10612.2 0.0485 16-Aug R.QEYEQLIAK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1120.5764 0.49 19011 10612 2 1120.581821 561.2955 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.53 2592.2 - 180709 - - - 4.802 - 1.607 0.34 - 230.1 1 2 0 0.0054 9 0 0 0 1.24E+07 2.50E+07 - - - 2.9229 0.994 230117_WJC_METTL3_WT_vs_EV_F03.10632.10632.2 0.2 12-Jun K.VLLAEYK.N sp|Q16513|PKN2_HUMAN 1 834.4851 0 19013 10632 2 834.485224 418.2498 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 5.97 2595.5 - 1.15E+06 - - - 0.1426 - 1.31 0.16 - 127.1 1 2 0 0.0001 7 0 0 0 6.10E+07 2.09E+10 - - - 1.0783 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.10637.10637.2 0.0177 14-Jun K.YVPLADVK[136.11].S "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 911.5208 0.84 19014 10637 2 911.521329 456.7677 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.83 2596.2 - 825121 - - - 0.6144 - 1.256 0.323 - 125 1 2 0 0.0006 8 0 0 0 5.79E+07 6.89E+07 - - - 2.1139 0.9859 230117_WJC_METTL3_WT_vs_EV_F03.10640.10640.2 0.165 12-Jun R.VLISSLK.D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 758.4902 0.92 19015 10640 2 758.4922 380.2524 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2596.6 - 263778 - - - 2.6487 - 1.294 0.088 - 96.6 1 2 0 0.002 7 0 0 0 9.10E+07 9.89E+07 - - - 0.507 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.10643.10643.2 0.344 12-Jul R.LPPDVLR.W sp|P78527|PRKDC_HUMAN 1 808.4807 14.75 19016 10643 2 808.481146 405.2476 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2597 - 703447 - - - 0.5653 - 1.381 0.179 - 184.5 1 2 0 0.0005 7 0 0 0 1.01E+09 6.87E+07 - - - 1.3858 0.9955 230117_WJC_METTL3_WT_vs_EV_F03.10657.10657.2 1.45 12-Jul R.VLISSLK[136.11].D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 766.5044 1.15 19020 10657 2 766.504787 384.2595 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2599 - 977322 - - - 0.5166 - 1.358 0.156 - 182.3 1 2 0 0.0004 7 0 0 0 8.91E+07 7.72E+07 - - - 1.1627 0.9853 230117_WJC_METTL3_WT_vs_EV_F03.10663.10663.2 1.1 14-Jul K.LLEATELK[136.11].G "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 923.5419 1.06 19024 10663 2 923.543443 462.7782 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 2599.7 - 637574 - - - 1.6729 - 1.332 0.043 - 110.2 1 2 0 0.0015 8 0 0 0 4.30E+07 4.06E+07 - - - 0.2227 0.9876 230117_WJC_METTL3_WT_vs_EV_F03.10667.10667.2 0.239 12-May K.SVLTPLR[166.11].G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 794.489 1.16 19026 10667 2 794.488987 398.2518 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2600.4 - 890376 - - - 0.0352 - 1.429 0.055 - 89.4 1 2 0 0 7 0 0 0 5.03E+07 4.32E+07 - - - 0.5783 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.10684.10684.2 0.101 12-Aug K.SVLTPLR.G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 784.4807 1.18 19032 10684 2 784.481327 393.2476 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2602.8 - 1.14E+06 - - - 0.8133 - 1.379 0.179 - 246.7 1 2 0 0.0006 7 0 0 0 5.22E+07 4.41E+07 - - - 1.3811 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.10687.10687.2 0.698 12-Jun R.LLDVYEK.E "sp|Q96EF6|FBX17_HUMAN,tr|M0R2C6|M0R2C6_HUMAN,tr|M0QZ95|M0QZ95_HUMAN" 3 878.4749 1.23 19033 10687 2 878.475487 440.2447 F-box only protein 17 OS=Homo sapiens OX=9606 GN=FBXO17 PE=1 SV=1 4.37 2603.2 - 319561 - - - 0.6295 - 1.493 0.276 - 83.9 1 2 0 0.0006 7 0 0 0 8.83E+06 7.20E+06 - - - 2.3493 0.9957 230117_WJC_METTL3_WT_vs_EV_F03.10703.10703.2 5.52 12-Jul R.IVEGILK.R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 770.4902 2.07 19038 10703 2 770.490923 386.2524 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 2605.5 - 1.35E+06 - - - 0.95 - 1.498 0.107 - 130 1 2 0 0.0007 7 0 0 0 6.82E+08 3.30E+08 - - - 1.1116 0.998 230117_WJC_METTL3_WT_vs_EV_F03.10708.10708.2 0.924 12-Aug R.IVEGILK[136.11].R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 778.5044 2.07 19041 10708 2 778.50508 390.2595 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 2606.2 - 1.31E+06 - - - 0.885 - 1.657 0.149 - 146.5 1 2 0 0.0007 7 0 0 0 6.82E+08 3.30E+08 - - - 1.7414 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.10710.10710.2 0.831 14-Aug R.ILLAVNGK.V sp|O15173|PGRC2_HUMAN 1 826.5276 1.59 19043 10710 2 826.528774 414.2711 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.75 2606.5 - 412985 - - - 1.3732 - 1.485 0.209 - 150.5 1 2 0 0.0011 8 0 0 0 3.94E+07 2.49E+07 - - - 1.7769 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.10723.10723.2 0.00109 26-Sep R.SLYASSPGGVYATR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1427.7045 1.84 19047 10723 2 1427.706229 714.8595 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2608.3 - 79945.6 - - - 1.2152 - 1.829 0.471 - 249.6 1 2 0 0.0017 14 0 0 0 7.24E+06 3.94E+06 - - - 4.0344 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.10724.10724.2 0.021 12-Aug K.MGITPLR.N "sp|Q12789|TF3C1_HUMAN,sp|O43325|LYRM1_HUMAN,tr|H3BNA8|H3BNA8_HUMAN" 3 786.4422 1.02 19048 10724 2 786.442716 394.2284 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 9.5 2608.5 - 611157 - - - 0.6625 - 1.664 0.202 - 224.6 1 2 0 0.0005 7 0 0 0 5.00E+07 4.89E+07 - - - 2.1463 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.10732.10732.2 0.0118 18-Sep R.IITEGFEAAK.E sp|P40227|TCPZ_HUMAN 1 1077.5706 9.28 19050 10732 2 1077.571771 539.7926 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 2609.6 - 286542 - - - 1.0626 - 1.698 0.341 - 172.1 1 2 0 0.0011 10 0 0 0 3.54E+07 3.82E+06 - - - 3.0371 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.10757.10757.2 0.141 12-Sep K.LTGMAFR.V "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 794.4109 2.76 19058 10757 2 794.412441 398.2127 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 9.75 2613.3 - 1.16E+06 - - - 1.9474 - 1.825 0.286 - 237.5 1 2 0 0.0015 7 0 0 0 1.14E+10 4.11E+09 - - - 3.0591 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.10761.10761.2 0.018 14-Jul R.VIQALAMK.G "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 872.5154 1.29 19060 10761 2 872.517159 437.265 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.72 2613.9 - 341448 - - - 2.0619 - 1.363 0.307 - 117 1 2 0 0.0018 8 0 0 0 2.04E+07 1.58E+07 - - - 2.2419 0.997 230117_WJC_METTL3_WT_vs_EV_F03.10766.10766.2 0.442 12-Jul K.LTGMAFR[166.11].V "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 804.4192 2.76 19062 10766 2 804.420638 403.2169 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 9.75 2614.5 - 1.58E+06 - - - 1.8324 - 1.467 0.157 - 151.8 1 2 0 0.0015 7 0 0 0 1.14E+10 4.11E+09 - - - 1.4144 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.10795.10795.2 0.0213 16-Jul K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 0.82 19071 10795 2 993.585681 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2618.8 - 189503 - - - 1.0377 - 1.513 0.331 - 117.6 1 2 0 0.001 9 0 0 0 7.26E+07 8.85E+07 - - - 2.6834 0.9885 230117_WJC_METTL3_WT_vs_EV_F03.10799.10799.2 19.1 12-Jul R.LIITQVR.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 841.5385 0.99 19072 10799 2 841.539075 421.7765 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 9.75 2619.4 - 6.46E+06 - - - 0.6381 - 1.344 0.064 - 180.2 1 2 0 0.0005 7 0 0 0 3.60E+08 3.63E+08 - - - 0.4503 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.10801.10801.2 1.35 12-Aug R.MGLVMDR[166.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 830.4018 2.27 19074 10801 2 830.401333 416.2082 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2619.6 - 528071 - - - -0.5624 - 1.642 0.198 - 232.8 1 2 0 -0.0005 7 0 0 0 1.24E+09 5.46E+08 - - - 2.0746 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.10805.10805.2 0.000461 14-Jul K.MMDIVAAK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 877.4401 1.69 19076 10805 2 877.441203 439.7273 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.59 2620.1 - 320266 - - - 1.2046 - 1.396 0.467 - 110 1 2 0 0.0011 8 0 0 0 1.34E+07 7.93E+06 - - - 3.4961 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.10806.10806.2 0.00757 16-Jul K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 0.82 19077 10806 2 983.575344 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2620.2 - 232384 - - - -1.0533 - 1.52 0.364 - 154.5 1 2 0 -0.001 9 0 0 0 7.26E+07 8.85E+07 - - - 2.9405 0.886 230117_WJC_METTL3_WT_vs_EV_F03.10815.10815.2 0.0242 16-Dec R.PGPLLVSAR[166.11].R sp|Q9NUL7|DDX28_HUMAN 1 918.5526 26.86 19081 10815 2 918.55584 460.2836 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 10.18 2621.5 - 543177 - - - 3.5044 - 1.924 0.265 - 374.2 1 1 0 0.0032 9 0 0 0 1.80E+09 6.72E+07 - - - 2.8905 0.9969 230117_WJC_METTL3_WT_vs_EV_F03.10819.10819.2 0.000491 12-Jul R.MGLVMDR.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 820.3935 2.27 19082 10819 2 820.392326 411.204 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2622 - 2.89E+06 - - - -1.4676 - 1.597 0.277 - 190.4 1 2 0 -0.0012 7 0 0 0 1.24E+09 5.46E+08 - - - 2.5698 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.10820.10820.2 1.30E-06 20-Sep K.FGDPVVQSDMK.H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1221.57 0.49 19083 10820 2 1221.569901 611.7923 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.21 2622.2 - 338721 - - - -0.0598 - 1.802 0.522 - 198.3 1 2 0 -0.0001 11 0 0 0 1.06E+07 2.15E+07 - - - 4.4896 1 230117_WJC_METTL3_WT_vs_EV_F03.10829.10829.2 2.55E-06 22-Dec R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 19087 10829 2 1474.776653 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2623.4 - 243944 - - - -0.9086 - 2.484 0.5 - 332.3 1 2 0 -0.0013 12 0 0 0 3.23E+07 0.00E+00 - - - 5.1276 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.10853.10853.2 0.0649 20-Aug K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 2954 19090 10853 2 1106.547432 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2627.2 - 254040 - - - 0.9308 - 1.651 0.301 - 134.9 1 2 0 0.001 11 0 0 0 2.06E+09 6.96E+05 - - - 2.6202 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.10871.10871.2 0.828 12-Jun R.LILPEAK.V "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN,tr|A8MSZ8|A8MSZ8_HUMAN" 3 782.4902 1.39 19092 10871 2 782.490861 392.2524 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 6 2630.2 - 758538 - - - 0.8562 - 1.094 0.268 - 119 1 2 0 0.0007 7 0 0 0 1.06E+08 7.58E+07 - - - 1.3049 0.9969 230117_WJC_METTL3_WT_vs_EV_F03.10874.10874.2 0.0264 16-Aug K.EIAEAYLGK.T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 992.5179 10.61 19093 10874 2 992.518487 497.2662 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 2630.6 - 1.53E+06 - - - 0.6297 - 1.391 0.194 - 226.7 1 2 0 0.0006 9 0 0 0 6.25E+07 5.89E+06 - - - 1.4285 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.10895.10895.2 0.00336 14-Aug R.VITALVER.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 899.544 0.36 19098 10895 2 899.544365 450.7793 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2633.6 - 1.18E+06 - - - 0.3869 - 1.581 0.254 - 206.3 1 2 0 0.0003 8 0 0 0 3.09E+09 8.67E+09 - - - 2.2984 0.9693 230117_WJC_METTL3_WT_vs_EV_F03.10897.10897.2 1.02 14-Jun R.VFVNPSLR[166.11].V sp|Q9HBH1|DEFM_HUMAN 1 940.537 1.06 19099 10897 2 940.537849 471.2758 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 9.72 2633.9 - 1.38E+06 - - - 0.9335 - 1.038 0.08 - 84.8 1 2 0 0.0009 8 0 0 0 3.68E+08 3.46E+08 - - - -0.2559 0.9929 230117_WJC_METTL3_WT_vs_EV_F03.10906.10906.2 0.954 12-May R.LPPDVLR.W sp|P78527|PRKDC_HUMAN 1 808.4807 2.18 19102 10906 2 808.481697 405.2476 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2635.1 - 547719 - - - 1.2468 - 1.166 0.161 - 90.9 1 2 0 0.001 7 0 0 0 7.53E+07 3.46E+07 - - - 0.7165 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.10915.10915.2 0.04 14-Jun R.AALLVPPR.Y sp|Q99959|PKP2_HUMAN 1 835.528 23.39 19106 10915 2 835.527567 418.7713 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 9.79 2636.2 - 244889 - - - -0.4859 - 1.345 0.337 - 88 1 2 0 -0.0004 8 0 0 0 2.46E+08 1.05E+07 - - - 2.4239 0.9641 230117_WJC_METTL3_WT_vs_EV_F03.10921.10921.2 1.09 14-Jul R.LPLETAYR[166.11].R "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 971.5316 11.74 19109 10921 2 971.532377 486.7731 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 6 2637.1 - 174292 - - - 0.8492 - 1.133 0.032 - 118.4 1 2 0 0.0008 8 0 0 0 4.99E+07 4.25E+06 - - - -0.3463 0.9829 230117_WJC_METTL3_WT_vs_EV_F03.10926.10926.2 0.0801 14-Jun R.LLVVTDPR[166.11].A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 921.5523 2.85 19110 10926 2 921.551776 461.7834 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.84 2637.8 - 903605 - - - -0.5545 - 1.348 0.088 - 94.4 1 2 0 -0.0005 8 0 0 0 1.56E+09 5.46E+08 - - - 0.5914 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.10933.10933.2 0.409 12-Jul R.LNELLVK.A "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L253|I3L253_HUMAN" 3 827.5117 2.15 19115 10933 2 827.511868 414.7631 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2638.6 - 1.30E+06 - - - 0.2586 - 1.672 0.214 - 162 1 2 0 0.0002 7 0 0 0 5.24E+08 2.44E+08 - - - 2.2502 0.996 230117_WJC_METTL3_WT_vs_EV_F03.10944.10944.2 0.184 12-Jul K.AC[160.03]TILLR.G "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 845.4793 12.63 19118 10944 2 845.479983 423.7469 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 8.29 2640.1 - 5.00E+06 - - - 0.7972 - 1.308 0.177 - 328.6 1 2 0 0.0007 7 0 0 0 4.03E+08 3.19E+07 - - - 1.1989 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.10954.10954.2 0.0176 14-Sep R.VITALVER[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 909.5523 0.36 19120 10954 2 909.552175 455.7834 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2641.6 - 1.94E+08 - - - -0.1231 - 1.878 0.384 - 298.8 1 2 0 -0.0001 8 0 0 0 3.08E+09 8.66E+09 - - - 3.7779 0.9886 230117_WJC_METTL3_WT_vs_EV_F03.10967.10967.2 0.533 12-Aug K.VFAVITK.K "sp|Q9UK97|FBX9_HUMAN,tr|H7C4H6|H7C4H6_HUMAN,tr|V9GZ74|V9GZ74_HUMAN" 3 776.4796 0.92 19123 10967 2 776.482803 389.2471 F-box only protein 9 OS=Homo sapiens OX=9606 GN=FBXO9 PE=1 SV=1 8.72 2643.6 - 552677 - - - 4.0915 - 1.455 0.153 - 194.4 1 2 0 0.0032 7 0 0 0 1.62E+07 1.75E+07 - - - 1.3583 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.10984.10984.2 0.0278 14-Aug R.VITALVER[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 909.5523 0.36 19129 10984 2 909.552875 455.7834 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2646 - 7.41E+07 - - - 0.6465 - 1.763 0.323 - 197.9 1 2 0 0.0006 8 0 0 0 3.08E+09 8.66E+09 - - - 3.1366 0.9539 230117_WJC_METTL3_WT_vs_EV_F03.10985.10985.2 4.35 14-Jul K.ILPVGGIK[136.11].E "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN,tr|K7ERR6|K7ERR6_HUMAN" 4 803.536 1.34 19130 10985 2 803.53663 402.7753 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 8.75 2646.1 - 543310 - - - 0.7529 - 0.99 0.067 - 113.3 1 2 0 0.0006 8 0 0 0 4.72E+07 3.54E+07 - - - -0.4946 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.10988.10988.2 0.0213 14-Jul R.VFVNPSLR.V sp|Q9HBH1|DEFM_HUMAN 1 930.5287 1.06 19131 10988 2 930.529448 466.2716 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 9.72 2646.5 - 1.13E+06 - - - 0.8028 - 1.515 0.284 - 195 1 2 0 0.0007 8 0 0 0 3.68E+08 3.46E+08 - - - 2.3913 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.10993.10993.2 0.204 14-Jul R.AIVPLEAR.M "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 867.5178 2.14 19133 10993 2 867.520341 434.7662 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 6.05 2647.1 - 517544 - - - 2.9267 - 1.436 0.226 - 196.8 2 2 0 0.0025 8 0 0 0 9.82E+07 4.59E+07 - - - 1.6663 0.933 230117_WJC_METTL3_WT_vs_EV_F03.10995.10995.2 0.0754 14-Jul Q.VLVLAPTR[166.11].E "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 877.5625 0.92 19135 10995 2 877.563682 439.7885 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.72 2647.4 - 420824 - - - 1.3948 - 1.445 0.317 - 172.5 1 1 0 0.0012 8 0 0 0 1.20E+08 1.30E+08 - - - 2.4922 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.11001.11001.2 0.00048 22-Sep K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 2.28 19138 11001 2 1222.671475 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2648.1 - 105967 - - - 5.4046 - 2.08 0.437 - 243.4 1 2 0 0.0066 12 0 0 0 9.42E+07 4.13E+07 - - - 4.1936 0.9704 230117_WJC_METTL3_WT_vs_EV_F03.11004.11004.2 0.674 18-May K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 1.62 19141 11004 2 1008.597913 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2648.5 - 192971 - - - 1.1224 - 0.919 0.146 - 66.5 2 2 0 0.0011 10 0 0 0 9.36E+06 5.78E+06 - - - -0.2512 0.9333 230117_WJC_METTL3_WT_vs_EV_F03.11007.11007.2 12.1 12-Jun R.LISVLNK.S "sp|Q9Y450|HBS1L_HUMAN,tr|H0YDX7|H0YDX7_HUMAN,tr|B7Z524|B7Z524_HUMAN,tr|J3QT46|J3QT46_HUMAN" 4 785.5011 0.5 19142 11007 2 785.502927 393.7578 HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1 8.75 2648.9 - 538969 - - - 2.3386 - 1.202 0.016 - 77.2 7 2 0 0.0018 7 0 0 0 3.47E+07 6.92E+07 - - - -0.6359 1 230117_WJC_METTL3_WT_vs_EV_F03.11009.11009.2 0.000114 22-Nov K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 2.28 19143 11009 2 1214.652819 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2649.2 - 656775 - - - 1.7717 - 2.22 0.486 - 386.9 1 2 0 0.0022 12 0 0 0 9.42E+07 4.14E+07 - - - 4.7283 0.8931 230117_WJC_METTL3_WT_vs_EV_F03.11026.11026.2 0.00525 14-Jun Q.VLVLAPTR.E "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 867.5542 0.92 19149 11026 2 867.556089 434.7844 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.72 2651.5 - 1.69E+06 - - - 2.1912 - 1.394 0.285 - 118.8 1 1 0 0.0019 8 0 0 0 1.20E+08 1.30E+08 - - - 2.1472 0.9969 230117_WJC_METTL3_WT_vs_EV_F03.11038.11038.2 0.106 18-Jul K.STVVPVPYEK.M "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1117.6019 0.96 19154 11038 2 1117.6054 559.8082 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.72 2653.3 - 171488 - - - 3.1084 - 1.236 0.313 - 128.7 1 2 0 0.0035 10 0 0 0 1.47E+07 1.54E+07 - - - 1.9431 0.9587 230117_WJC_METTL3_WT_vs_EV_F03.11046.11046.2 2.29 16-May R.VDTDFMQLK[136.11].K "sp|Q9H6P5|TASP1_HUMAN,tr|Q5JWM4|Q5JWM4_HUMAN" 2 1103.5412 0.04 19156 11046 2 1103.541335 552.7779 Threonine aspartase 1 OS=Homo sapiens OX=9606 GN=TASP1 PE=1 SV=1 4.21 2654.4 - 526552 - - - 0.0806 - 0.969 0.126 - 68.2 2 2 0 0.0001 9 0 0 0 8.59E+05 1.92E+07 - - - -0.254 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.11051.11051.2 0.0618 12-Jun R.LIPTELR.R "sp|Q96G21|IMP4_HUMAN,tr|F8WCN0|F8WCN0_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN" 4 840.5069 1.03 19158 11051 2 840.508029 421.2607 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2655.1 - 1.61E+06 - - - 1.3397 - 1.294 0.313 - 152.5 1 2 0 0.0011 7 0 0 0 1.65E+08 1.60E+08 - - - 2.1691 0.9951 230117_WJC_METTL3_WT_vs_EV_F03.11077.11077.2 0.595 14-Jul K.GIYALAAR.D "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 833.4759 0.75 19163 11077 2 833.477848 417.7452 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 8.75 2659.3 - 625528 - - - 2.2916 - 1.437 0.168 - 148.7 3 2 0 0.0019 8 0 0 0 6.03E+07 8.05E+07 - - - 1.1616 0.9949 230117_WJC_METTL3_WT_vs_EV_F03.11090.11090.2 0.668 12-Jul K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 0.96 19169 11090 2 828.474814 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2661 - 907947 - - - 1.8178 - 1.449 0.107 - 174.5 1 2 0 0.0015 7 0 0 0 3.26E+10 3.39E+10 - - - 1.006 0.9444 230117_WJC_METTL3_WT_vs_EV_F03.11097.11097.2 11.6 12-Jul K.FIEIAAR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 818.465 0.96 19172 11097 2 818.464648 410.2398 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2662 - 2.33E+06 - - - -0.4765 - 1.148 0.037 - 121.3 1 2 0 -0.0004 7 0 0 0 3.27E+10 3.40E+10 - - - -0.2485 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.11101.11101.2 0.115 20-Jul K.IGGIGTVPVGR.V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1024.6029 4.83 19174 11101 2 1024.603173 513.3087 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2662.4 - 281350 - - - 0.2381 - 1.546 0.262 - 98.8 1 2 0 0.0002 11 0 0 0 8.06E+07 1.67E+07 - - - 2.1546 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.11106.11106.2 0.00751 12-Jul K.DDAMLLK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 804.4051 1.25 19176 11106 2 804.405942 403.2098 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.21 2663.1 - 1.15E+06 - - - 0.997 - 1.525 0.327 - 238.3 1 2 0 0.0008 7 0 0 0 3.83E+07 3.06E+07 - - - 2.7931 0.9907 230117_WJC_METTL3_WT_vs_EV_F03.11110.11110.2 1.8 12-Jul K.SVLIMGR.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 774.4422 1.47 19178 11110 2 774.443594 388.2284 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.47 2663.5 - 1.02E+06 - - - 1.8065 - 1.228 0.118 - 181.1 1 2 0 0.0014 7 0 0 0 9.18E+07 6.23E+07 - - - 0.5629 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.11125.11125.2 0.0388 14-Aug K.AVVAALMK[136.11].A sp|P08240|SRPRA_HUMAN 1 809.4924 1.15 19184 11125 2 809.492745 405.7535 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 8.8 2665.8 - 481564 - - - 0.3694 - 1.527 0.182 - 209 1 2 0 0.0003 8 0 0 0 8.00E+07 6.98E+07 - - - 1.6618 0.998 230117_WJC_METTL3_WT_vs_EV_F03.11133.11133.2 0.878 14-Jul K.IGVTVLSR[166.11].L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 853.5261 0.92 19187 11133 2 853.525908 427.7703 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2666.8 - 1.83E+06 - - - -0.1921 - 1.663 0.217 - 119.9 1 2 0 -0.0002 8 0 0 0 4.37E+08 4.74E+08 - - - 2.1777 0.9533 230117_WJC_METTL3_WT_vs_EV_F03.11141.11141.2 1.78 12-Jun K.IIPVVVK.M "sp|Q96KG9|SCYL1_HUMAN,tr|E9PPN3|E9PPN3_HUMAN,tr|E9PK59|E9PK59_HUMAN,tr|E9PS17|E9PS17_HUMAN" 4 766.5317 1.67 19190 11141 2 766.530607 384.2731 N-terminal kinase-like protein OS=Homo sapiens OX=9606 GN=SCYL1 PE=1 SV=1 8.75 2667.9 - 988752 - - - -1.375 - 0.927 0.195 - 92.9 1 2 0 -0.0011 7 0 0 0 4.36E+07 2.61E+07 - - - 0.2408 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.11155.11155.2 0.00131 14-Sep K.IGVTVLSR.L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 843.5178 0.92 19195 11155 2 843.516225 422.7662 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2669.7 - 4.15E+06 - - - -1.8696 - 1.836 0.299 - 275 1 2 0 -0.0016 8 0 0 0 4.37E+08 4.74E+08 - - - 3.0814 0.9441 230117_WJC_METTL3_WT_vs_EV_F03.11162.11162.2 0.579 12-Jul R.VYLGALK[136.11].Y sp|Q6P2Q9|PRP8_HUMAN 1 770.4782 1.08 19196 11162 2 770.476341 386.2464 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.56 2670.8 - 1.35E+06 - - - -2.3816 - 1.27 0.102 - 165.6 1 2 0 -0.0018 7 0 0 0 2.28E+08 2.11E+08 - - - 0.5511 0.9414 230117_WJC_METTL3_WT_vs_EV_F03.11169.11169.2 1.98 12-May R.VYLGALK.Y sp|Q6P2Q9|PRP8_HUMAN 1 762.464 0.77 19197 11169 2 762.463646 382.2393 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.56 2671.9 - 1.36E+06 - - - -0.4328 - 1.064 0.117 - 79.9 8 2 0 -0.0003 7 0 0 0 2.55E+08 3.31E+08 - - - -0.3018 0.985 230117_WJC_METTL3_WT_vs_EV_F03.11182.11182.2 5.48 12-Sep K.LGITQLR.F "sp|Q9Y285|SYFA_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 3 799.4916 2.43 19199 11182 2 799.490898 400.7531 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 9.75 2673.9 - 2.05E+06 - - - -0.863 - 1.758 0 - 228.8 1 2 0 -0.0007 7 0 0 0 1.57E+08 6.45E+07 - - - 0.8284 0.9925 230117_WJC_METTL3_WT_vs_EV_F03.11189.11189.2 0.611 14-Jul R.ILMGSTLR[166.11].K "sp|P10644|KAP0_HUMAN,sp|P31321|KAP1_HUMAN,tr|K7EM13|K7EM13_HUMAN,tr|C9JSK5|C9JSK5_HUMAN,tr|K7EKR1|K7EKR1_HUMAN,tr|K7EPB2|K7EPB2_HUMAN,tr|H7BYW5|H7BYW5_HUMAN" 7 899.5138 1.79 19202 11189 2 899.513655 450.7642 cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1A PE=1 SV=1 9.75 2674.8 - 686559 - - - -0.1534 - 1.222 0.187 - 125.7 1 2 0 -0.0001 8 0 0 0 3.47E+07 1.94E+07 - - - 1.0268 0.9872 230117_WJC_METTL3_WT_vs_EV_F03.11199.11199.2 0.926 12-Jun R.VTVPLVR[166.11].R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 792.5097 0.97 19206 11199 2 792.508745 397.2621 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2676.2 - 2.66E+06 - - - -1.1975 - 1.316 0.162 - 146.2 1 2 0 -0.0009 7 0 0 0 4.23E+08 4.36E+08 - - - 1.1073 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.11206.11206.2 0.033 12-Jul R.VTVPLVR.R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 782.5014 0.98 19208 11206 2 782.501035 392.258 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2677.1 - 3.40E+06 - - - -0.4971 - 1.492 0.236 - 208.1 1 2 0 -0.0004 7 0 0 0 4.26E+08 4.37E+08 - - - 2.0518 0.9522 230117_WJC_METTL3_WT_vs_EV_F03.11210.11210.2 1.2 12-Jul K.LPYSTFR.T "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 882.46 1.18 19209 11210 2 882.458396 442.2373 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.75 2677.7 - 1.04E+06 - - - -1.7644 - 1.036 0.168 - 204.5 1 2 0 -0.0016 7 0 0 0 1.94E+08 1.64E+08 - - - 0.3934 0.917 230117_WJC_METTL3_WT_vs_EV_F03.11216.11216.2 0.0458 14-Sep K.LTGVFAPR.P "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 859.4916 0.99 19210 11216 2 859.490907 430.7531 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2678.6 - 4.71E+06 - - - -0.7923 - 1.887 0.315 - 332.9 1 1 0 -0.0007 8 0 0 0 2.28E+09 2.31E+09 - - - 3.2825 0.9802 230117_WJC_METTL3_WT_vs_EV_F03.11221.11221.2 0.255 14-Aug K.LVPVLSAK[136.11].A "sp|P37837|TALDO_HUMAN,tr|F2Z393|F2Z393_HUMAN" 2 833.5466 1.63 19212 11221 2 833.544473 417.7806 Transaldolase OS=Homo sapiens OX=9606 GN=TALDO1 PE=1 SV=2 8.75 2679.3 - 941188 - - - -2.5398 - 1.137 0.272 - 169.7 1 2 0 -0.0021 8 0 0 0 5.31E+07 3.27E+07 - - - 1.4366 0.9098 230117_WJC_METTL3_WT_vs_EV_F03.11223.11223.2 0.0194 14-May K.VENLFNEK.C "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 991.4975 1.12 19213 11223 2 991.494948 496.756 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2679.5 - 150368 - - - -2.5346 - 1.302 0.058 - 71.2 1 2 0 -0.0025 8 0 0 0 4.97E+06 4.44E+06 - - - 0.2645 0.9946 230117_WJC_METTL3_WT_vs_EV_F03.11230.11230.2 0.0728 12-Jun K.LPYSTFR[166.11].T "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 892.4682 1.18 19214 11230 2 892.469271 447.2414 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.75 2680.6 - 2.33E+06 - - - 1.1743 - 1.069 0.226 - 140.4 1 2 0 0.001 7 0 0 0 1.94E+08 1.64E+08 - - - 0.9213 0.9252 230117_WJC_METTL3_WT_vs_EV_F03.11234.11234.2 0.187 16-May K.VVILGSGVR.K "sp|Q8NEZ4|KMT2C_HUMAN,tr|A0A804HKS3|A0A804HKS3_HUMAN,tr|A0A804HJU5|A0A804HJU5_HUMAN,tr|A0A804HJR9|A0A804HJR9_HUMAN,tr|H7BY37|H7BY37_HUMAN,tr|A0A7P0TAI3|A0A7P0TAI3_HUMAN,tr|A0A7P0T9K8|A0A7P0T9K8_HUMAN,tr|H0Y765|H0Y765_HUMAN,tr|H7C2V8|H7C2V8_HUMAN,tr|A0A804HKW4|A0A804HKW4_HUMAN,tr|A0A804HLD4|A0A804HLD4_HUMAN,tr|A0A804HIK3|A0A804HIK3_HUMAN,tr|A0A804HI08|A0A804HI08_HUMAN,tr|A0A7P0T8F0|A0A7P0T8F0_HUMAN" 14 898.56 0.42 19216 11234 2 898.56125 450.2873 Histone-lysine N-methyltransferase 2C OS=Homo sapiens OX=9606 GN=KMT2C PE=1 SV=3 9.72 2681.1 - 248400 - - - 1.3889 - 1.065 0.007 - 55.6 2 2 0 0.0012 9 0 0 0 3.46E+06 8.31E+06 - - - -0.86 0.998 230117_WJC_METTL3_WT_vs_EV_F03.11276.11276.2 0.00772 18-Jul K.NGQDLGVAFK[136.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1055.5491 1.4 19227 11276 2 1055.547487 528.7818 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2687.4 - 150854 - - - -1.5366 - 1.512 0.398 - 179.7 1 2 0 -0.0016 10 0 0 0 5.11E+07 3.66E+07 - - - 3.1341 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.11302.11302.2 0.0529 12-Jun K.FMTDPIR.L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 878.432 0.9 19236 11302 2 878.433278 440.2233 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2691 - 1.16E+06 - - - 1.4275 - 1.225 0.271 - 172.6 1 2 0 0.0013 7 0 0 0 1.05E+08 1.17E+08 - - - 1.6852 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.11304.11304.2 0.237 12-Jul K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 1.59 19237 11304 2 828.474508 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2691.2 - 2.52E+06 - - - 1.4484 - 1.531 0.161 - 186.9 1 2 0 0.0012 7 0 0 0 2.26E+08 1.42E+08 - - - 1.5793 0.9798 230117_WJC_METTL3_WT_vs_EV_F03.11311.11311.2 0.269 12-Jul K.FIEIAAR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 818.465 1.12 19239 11311 2 818.466557 410.2398 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2692.2 - 2.42E+06 - - - 1.8559 - 1.348 0.025 - 118.9 2 2 0 0.0015 7 0 0 0 1.08E+08 9.59E+07 - - - 0.0369 0.9725 230117_WJC_METTL3_WT_vs_EV_F03.11316.11316.2 7.19 12-Nov K.LAC[160.03]LLC[160.03]R[166.11].R "sp|P78332|RBM6_HUMAN,sp|P98175|RBM10_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 3 914.4705 0.39 19240 11316 2 914.471127 458.2426 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 8.07 2693 - 1.11E+06 - - - 0.6321 - 1.273 0.008 - 554.4 1 2 0 0.0006 7 0 0 0 8.46E+06 2.16E+07 - - - -0.1353 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.11318.11318.2 0.00061 14-Sep K.FGPALSVK[136.11].V "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 825.484 4.06 19241 11318 2 825.485672 413.7493 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.75 2693.2 - 1.96E+06 - - - 2.0376 - 1.849 0.398 - 234.7 1 2 0 0.0017 8 0 0 0 2.53E+09 6.24E+08 - - - 3.8338 0.9907 230117_WJC_METTL3_WT_vs_EV_F03.11324.11324.2 0.069 12-Jul K.FMTDPIR[166.11].L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 888.4403 0.98 19244 11324 2 888.442425 445.2274 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2694 - 2.35E+06 - - - 2.3986 - 1.018 0.219 - 182.7 1 2 0 0.0021 7 0 0 0 1.15E+08 1.17E+08 - - - 0.7144 0.998 230117_WJC_METTL3_WT_vs_EV_F03.11330.11330.2 0.192 14-Jun K.VLEC[160.03]DIIK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 988.5263 0.82 19247 11330 2 988.527474 495.2704 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 2694.7 - 108356 - - - 1.1694 - 1.252 0.27 - 90 1 2 0 0.0012 8 0 0 0 7.41E+06 9.05E+06 - - - 1.7127 0.9832 230117_WJC_METTL3_WT_vs_EV_F03.11334.11334.2 0.688 14-Sep R.NLLLAGAK[136.11].V sp|Q9P2R3|ANFY1_HUMAN 1 806.5105 3.54 19249 11334 2 806.512702 404.2625 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 8.75 2695.2 - 234505 - - - 2.6819 - 1.431 0.038 - 218.1 1 2 0 0.0022 8 0 0 0 5.91E+07 1.67E+07 - - - 0.4018 0.9905 230117_WJC_METTL3_WT_vs_EV_F03.11340.11340.2 0.0662 12-Jun R.IVYLYTK.K sp|P49207|RL34_HUMAN 1 898.5164 0.75 19252 11340 2 898.52102 450.2655 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 8.5 2695.9 - 915550 - - - 5.1362 - 1.464 0.259 - 115.4 1 2 0 0.0046 7 0 0 0 7.22E+08 9.61E+08 - - - 2.1603 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.11347.11347.2 0.0189 12-Jul R.IVYLYTK[136.11].K sp|P49207|RL34_HUMAN 1 906.5306 0.75 19256 11347 2 906.53295 454.2726 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 8.5 2696.7 - 3.43E+06 - - - 2.5868 - 1.587 0.355 - 172 1 2 0 0.0023 7 0 0 0 7.21E+08 9.61E+08 - - - 3.1257 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.11349.11349.2 0.126 20-Jul K.ETTIDGEELVK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1240.6278 1.61 19258 11349 2 1240.630416 621.3212 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4 2697 - 128089 - - - 2.0981 - 1.213 0.24 - 120.4 1 2 0 0.0026 11 0 0 0 4.51E+06 2.80E+06 - - - 1.3352 0.9967 230117_WJC_METTL3_WT_vs_EV_F03.11352.11352.2 0.0935 14-Jul K.ALSVGLVK.G "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 3 785.5011 1.68 19259 11352 2 785.50308 393.7578 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 8.8 2697.4 - 744768 - - - 2.5334 - 1.466 0.187 - 140.6 1 2 0 0.002 8 0 0 0 9.94E+07 5.90E+07 - - - 1.5753 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.11357.11357.2 1.12 14-Jun R.VLAVTAIR.E sp|P22102|PUR2_HUMAN 1 841.5385 2.5 19262 11357 2 841.539869 421.7765 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2698.1 - 1.62E+06 - - - 1.5816 - 1.672 0.221 - 137.3 1 2 0 0.0013 8 0 0 0 3.35E+08 1.34E+08 - - - 2.2232 0.9959 230117_WJC_METTL3_WT_vs_EV_F03.11358.11358.2 0.905 14-Aug R.VLAVTAIR[166.11].E sp|P22102|PUR2_HUMAN 1 851.5468 2.5 19263 11358 2 851.548518 426.7807 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2698.2 - 971885 - - - 2.0081 - 1.598 0.102 - 165.1 1 2 0 0.0017 8 0 0 0 3.35E+08 1.34E+08 - - - 1.2076 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.11362.11362.2 0.0674 18-Jul K.NGQDLGVAFK.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1047.5349 1.27 19265 11362 2 1047.537053 524.7747 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2698.6 - 328445 - - - 2.0467 - 1.375 0.242 - 164.3 1 2 0 0.0021 10 0 0 0 4.64E+07 3.66E+07 - - - 1.7166 0.9175 230117_WJC_METTL3_WT_vs_EV_F03.11366.11366.2 4.59 12-May K.MMEIMTR.E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 910.4075 0.87 19267 11366 2 910.410373 456.211 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2699.2 - 1.76E+06 - - - 3.1942 - 0.916 0.121 - 42.5 2 2 0 0.0029 7 0 0 0 1.25E+08 1.44E+08 - - - -0.4787 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.11373.11373.2 0.0043 12-Jul K.MMEIMTR[166.11].E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 920.4157 0.87 19272 11373 2 920.417092 461.2151 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2700.1 - 638213 - - - 1.4743 - 1.446 0.209 - 237.6 1 2 0 0.0014 7 0 0 0 1.25E+08 1.44E+08 - - - 1.7528 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.11380.11380.2 0.0037 16-Oct R.MVGGVLVER[166.11].T sp|Q9UHV9|PFD2_HUMAN 1 968.5353 0.28 19275 11380 2 968.537584 485.2749 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 5.75 2701.1 - 1.43E+06 - - - 2.4026 - 1.686 0.384 - 230.8 1 2 0 0.0023 9 0 0 0 6.61E+07 2.36E+08 - - - 3.3877 0.9541 230117_WJC_METTL3_WT_vs_EV_F03.11386.11386.2 2.12 14-Jul K.IVGYVLAK.M "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN" 4 861.5324 1.36 19279 11386 2 861.531976 431.7735 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 8.59 2701.8 - 714856 - - - -0.4805 - 1.017 0.107 - 89.5 1 2 0 -0.0004 8 0 0 0 1.70E+08 1.25E+08 - - - -0.118 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.11387.11387.2 0.000442 18-Oct K.YEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1178.5932 201.09 19280 11387 2 1178.594072 590.3039 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2701.9 - 158508 - - - 0.7806 - 2.157 0.293 - 431.3 1 2 0 0.0009 10 0 0 0 2.35E+07 1.17E+05 - - - 3.3505 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.11388.11388.2 0.0121 18-May K.C[160.03]PFTGNVSIR[166.11].G "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1159.5683 0.96 19281 11388 2 1159.571635 580.7915 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.25 2702.1 - 128155 - - - 2.8347 - 1.148 0.383 - 86.1 1 2 0 0.0033 10 0 0 0 3.23E+06 3.36E+06 - - - 2.2541 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.11392.11392.2 0.00064 12-Aug K.MMVAGFK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 790.3961 0.88 19283 11392 2 790.397017 396.2053 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2702.6 - 2.77E+06 - - - 1.1576 - 1.625 0.439 - 315.4 1 2 0 0.0009 7 0 0 0 5.62E+09 6.41E+09 - - - 3.8215 0.9549 230117_WJC_METTL3_WT_vs_EV_F03.11393.11393.2 4.96 12-Jun R.FAGVDIR.V "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 776.4181 2.45 19284 11393 2 776.418011 389.2163 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 5.84 2702.7 - 1.10E+06 - - - -0.0992 - 1.111 0.093 - 92.4 5 2 0 -0.0001 7 0 0 0 3.68E+07 1.50E+07 - - - -0.2508 0.9916 230117_WJC_METTL3_WT_vs_EV_F03.11394.11394.2 1.37 12-Jul K.YLDEIVK.E sp|P12270|TPR_HUMAN 1 878.4749 1.05 19285 11394 2 878.475928 440.2447 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.37 2702.8 - 617908 - - - 1.1304 - 1.18 0.14 - 130.4 1 2 0 0.001 7 0 0 0 3.72E+07 3.54E+07 - - - 0.5992 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.11398.11398.3 0.0048 Aug-52 K.SQIHDIVLVGGSTR.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1480.7998 85.24 19287 11398 3 1480.802919 494.6072 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2703.3 - 158021 - - - 2.1124 - 1.779 0.307 - 69.5 1 2 0 0.0031 14 0 0 0 1.47E+07 1.73E+05 - - - 3.4928 0.991 230117_WJC_METTL3_WT_vs_EV_F03.11403.11403.2 2.04 14-Jul K.IVGYVLAK[136.11].M "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN" 4 869.5466 1.36 19288 11403 2 869.547133 435.7806 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 8.59 2704.1 - 1.48E+06 - - - 0.6245 - 1.146 0.159 - 111.6 1 2 0 0.0005 8 0 0 0 1.70E+08 1.25E+08 - - - 0.6262 0.9021 230117_WJC_METTL3_WT_vs_EV_F03.11409.11409.2 12.4 14-Jul R.K[136.11]QNLLASR.E "sp|O00555|CAC1A_HUMAN,tr|A0A1B0GTI4|A0A1B0GTI4_HUMAN,tr|A0A1C7CYY9|A0A1C7CYY9_HUMAN,tr|A0A1B0GU81|A0A1B0GU81_HUMAN,tr|A0A590UJK2|A0A590UJK2_HUMAN,tr|B5TYJ1|B5TYJ1_HUMAN,tr|A0A1B0GTW2|A0A1B0GTW2_HUMAN,tr|A0A384DVW2|A0A384DVW2_HUMAN,tr|A0A1B0GTN7|A0A1B0GTN7_HUMAN,tr|A0A087WW63|A0A087WW63_HUMAN,tr|A0A1B0GU74|A0A1B0GU74_HUMAN,tr|A0A1B0GUS3|A0A1B0GUS3_HUMAN" 12 936.5596 - 19290 11409 2 936.560033 469.2871 Voltage-dependent P\Q-type calcium channel subunit alpha-1A OS=Homo sapiens OX=9606 GN=CACNA1A PE=1 SV=3 11 2705 - 1.08E+06 - - - 0.4474 - 1.086 0.028 - 71.1 9 2 0 0.0004 8 0 0 0 - - - - - -0.9298 0.9942 230117_WJC_METTL3_WT_vs_EV_F03.11419.11419.2 0.447 14-Jul R.GLGGIMVK.R sp|O94776|MTA2_HUMAN 1 773.4469 1.2 19294 11419 2 773.448027 387.7307 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 2706.3 - 979838 - - - 1.3976 - 1.172 0.182 - 133.8 1 2 0 0.0011 8 0 0 0 4.55E+07 3.81E+07 - - - 0.8636 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.11470.11470.2 0.219 14-Jun R.VILPDDVR.D "sp|Q3YEC7|RABL6_HUMAN,tr|F2Z2T0|F2Z2T0_HUMAN,tr|H0Y7H6|H0Y7H6_HUMAN,tr|G3V154|G3V154_HUMAN" 4 925.5233 45 19304 11470 2 925.52481 463.7689 Rab-like protein 6 OS=Homo sapiens OX=9606 GN=RABL6 PE=1 SV=2 4.21 2714 - 1.71E+06 - - - 1.651 - 1.312 0.362 - 59.6 1 2 0 0.0015 8 0 0 0 4.73E+07 1.05E+06 - - - 2.5332 0.9046 230117_WJC_METTL3_WT_vs_EV_F03.11479.11479.2 12.8 12-Aug K.LAPFIAK[136.11].R "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN,tr|K7ELX4|K7ELX4_HUMAN" 3 766.4833 1.64 19307 11479 2 766.481649 384.2489 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 8.75 2715.2 - 2.08E+06 - - - -2.1031 - 1.325 0.015 - 166.7 1 2 0 -0.0016 7 0 0 0 3.44E+08 2.09E+08 - - - 0.043 0.9813 230117_WJC_METTL3_WT_vs_EV_F03.11491.11491.2 0.0386 14-Jun R.TIAPIIGR.T sp|Q99459|CDC5L_HUMAN 1 839.5229 1.1 19314 11491 2 839.523876 420.7687 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.41 2716.8 - 345213 - - - 1.1769 - 1.308 0.027 - 94.9 1 2 0 0.001 8 0 0 0 2.06E+07 1.88E+07 - - - 0.0499 0.9884 230117_WJC_METTL3_WT_vs_EV_F03.11511.11511.2 0.122 14-May R.LLVPGTYK[136.11].L "sp|O75976|CBPD_HUMAN,tr|J3QQJ4|J3QQJ4_HUMAN" 2 897.5415 0.77 19317 11511 2 897.540099 449.778 Carboxypeptidase D OS=Homo sapiens OX=9606 GN=CPD PE=1 SV=2 8.59 2720 - 169084 - - - -1.5654 - 1.167 0.253 - 58 1 2 0 -0.0014 8 0 0 0 1.19E+07 1.55E+07 - - - 1.375 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.11525.11525.2 0.00638 16-Sep R.LLSPLSSAR[166.11].L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 952.5581 1.09 19326 11525 2 952.558874 477.2863 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 2721.7 - 1.33E+06 - - - 0.8115 - 1.701 0.224 - 220.8 1 2 0 0.0008 9 0 0 0 1.82E+08 1.66E+08 - - - 2.2321 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.11530.11530.2 0.574 14-Sep R.TIAPIIGR[166.11].T sp|Q99459|CDC5L_HUMAN 1 849.5312 1.84 19329 11530 2 849.53213 425.7729 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.41 2722.4 - 643861 - - - 1.1442 - 1.44 0.245 - 286.7 1 2 0 0.001 8 0 0 0 3.83E+07 2.08E+07 - - - 1.95 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.11538.11538.2 0.0128 14-Jun K.GLYPAPLK[136.11].L "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 865.5153 1.73 19333 11538 2 865.51662 433.7649 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.59 2723.4 - 455705 - - - 1.5367 - 1.397 0.246 - 119.1 1 2 0 0.0013 8 0 0 0 5.30E+07 3.07E+07 - - - 1.8659 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.11548.11548.2 0.0443 16-Sep R.LLSPLSSAR.L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 942.5498 1.1 19338 11548 2 942.55144 472.2822 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 2724.6 - 2.60E+06 - - - 1.7071 - 1.832 0.237 - 302.2 1 2 0 0.0016 9 0 0 0 1.82E+08 1.65E+08 - - - 2.5425 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.11551.11551.2 0.0219 16-Sep R.LLPAELPAK[136.11].R sp|P78527|PRKDC_HUMAN 1 958.5943 1.21 19339 11551 2 958.599373 480.3044 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2725 - 333808 - - - 5.3255 - 1.62 0.442 - 227.3 1 2 0 0.0051 9 0 0 0 4.89E+07 4.03E+07 - - - 3.6997 0.9866 230117_WJC_METTL3_WT_vs_EV_F03.11556.11556.2 2.14 12-Jul K.IIVDELK[136.11].Q "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|H0Y9P0|H0Y9P0_HUMAN,tr|D6RF23|D6RF23_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 9 836.5099 1.04 19341 11556 2 836.510993 419.2622 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 4.37 2725.6 - 784501 - - - 1.3425 - 1.355 0.036 - 117.7 1 2 0 0.0011 7 0 0 0 6.24E+08 6.02E+08 - - - 0.2692 0.9883 230117_WJC_METTL3_WT_vs_EV_F03.11558.11558.2 1.79 14-May R.IGLETSLR[166.11].Y sp|Q9Y230|RUVB2_HUMAN 1 897.5159 1.75 19343 11558 2 897.515235 449.7652 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6 2725.9 - 258565 - - - -0.7432 - 1.265 0.182 - 55.7 2 2 0 -0.0007 8 0 0 0 3.91E+07 2.23E+07 - - - 0.9595 0.9643 230117_WJC_METTL3_WT_vs_EV_F03.11561.11561.2 4.19 14-Jun K.GLYPAPLK.L "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 857.5011 1.71 19344 11561 2 857.503042 429.7578 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.59 2726.3 - 498242 - - - 2.2764 - 1.056 0.093 - 105 2 2 0 0.002 8 0 0 0 5.33E+07 3.13E+07 - - - -0.2429 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.11562.11562.2 0.000128 12-Jun K.C[160.03]PVFVVR.W "sp|Q9C0J8|WDR33_HUMAN,tr|C9J8B4|C9J8B4_HUMAN" 2 875.4687 1.7 19345 11562 2 875.469636 438.7416 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 8.25 2726.4 - 442164 - - - 1.0189 - 1.531 0.475 - 145.8 1 2 0 0.0009 7 0 0 0 9.21E+07 5.42E+07 - - - 3.8986 0.8504 230117_WJC_METTL3_WT_vs_EV_F03.11565.11565.2 0.136 16-Aug N.LVIITAGAR[166.11].Q "sp|Q9BYZ2|LDH6B_HUMAN,sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 7 922.5839 0.96 19346 11565 2 922.586249 462.2992 L-lactate dehydrogenase A-like 6B OS=Homo sapiens OX=9606 GN=LDHAL6B PE=1 SV=3 9.75 2726.8 - 1.63E+06 - - - 2.5223 - 1.642 0.197 - 172.8 1 1 0 0.0023 9 0 0 0 1.66E+08 1.72E+08 - - - 1.93 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.11575.11575.2 0.42 12-Jul R.IDGVLIR.M sp|O75663|TIPRL_HUMAN 1 784.4807 2.87 19349 11575 2 784.481928 393.2476 TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2 5.84 2728.2 - 701461 - - - 1.5794 - 1.591 0.179 - 112.5 1 2 0 0.0012 7 0 0 0 7.31E+07 2.54E+07 - - - 1.8341 0.9731 230117_WJC_METTL3_WT_vs_EV_F03.11580.11580.2 3.62 12-May R.FPGAYLK.G "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 794.4327 1.41 19350 11580 2 794.434641 398.2236 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.59 2728.9 - 933204 - - - 2.4735 - 1.147 0.123 - 52.4 7 2 0 0.002 7 0 0 0 9.69E+07 6.86E+07 - - - 0.0059 0.9906 230117_WJC_METTL3_WT_vs_EV_F03.11584.11584.2 0.278 12-May K.IIVDELK.Q "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|H0Y9P0|H0Y9P0_HUMAN,tr|D6RF23|D6RF23_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 9 828.4957 1.04 19352 11584 2 828.497521 415.2551 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 4.37 2729.5 - 5.69E+06 - - - 2.2342 - 1.311 0.12 - 65.8 2 2 0 0.0019 7 0 0 0 6.23E+08 6.02E+08 - - - 0.6503 0.9907 230117_WJC_METTL3_WT_vs_EV_F03.11586.11586.2 0.274 12-Jul R.VAGIFPR[166.11].L "sp|O96005|CLPT1_HUMAN,tr|K7EJ16|K7EJ16_HUMAN" 2 768.4522 0.79 19353 11586 2 768.453085 385.2334 Cleft lip and palate transmembrane protein 1 OS=Homo sapiens OX=9606 GN=CLPTM1 PE=1 SV=1 9.72 2729.7 - 996118 - - - 1.179 - 1.252 0.105 - 163 1 2 0 0.0009 7 0 0 0 5.36E+07 6.83E+07 - - - 0.5284 0.8909 230117_WJC_METTL3_WT_vs_EV_F03.11597.11597.2 0.0575 16-Sep N.LVIITAGAR.Q "sp|Q9BYZ2|LDH6B_HUMAN,sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 7 912.5757 0.96 19357 11597 2 912.577722 457.2951 L-lactate dehydrogenase A-like 6B OS=Homo sapiens OX=9606 GN=LDHAL6B PE=1 SV=3 9.75 2731.3 - 7.87E+06 - - - 2.2683 - 1.629 0.231 - 145.5 1 1 0 0.0021 9 0 0 0 1.66E+08 1.72E+08 - - - 2.1582 0.976 230117_WJC_METTL3_WT_vs_EV_F03.11604.11604.2 5.48 12-Jul R.FPGAYLK[136.11].G "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 802.4469 1.46 19361 11604 2 802.449265 402.2307 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.59 2732.2 - 555708 - - - 2.9771 - 1.12 0.118 - 144.5 1 2 0 0.0024 7 0 0 0 8.90E+07 6.11E+07 - - - 0.2709 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.11618.11618.2 0.0713 12-Jul K.LLQEIVR.S "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 869.5335 1.47 19364 11618 2 869.534669 435.774 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6 2734.3 - 1.73E+06 - - - 1.3996 - 1.504 0.221 - 170.3 1 2 0 0.0012 7 0 0 0 7.32E+07 5.00E+07 - - - 1.9661 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.11629.11629.2 0.11 14-Oct K.LINAVELK[136.11].K sp|P56192|SYMC_HUMAN 1 906.563 1.08 19368 11629 2 906.56468 454.2888 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6 2735.8 - 3.67E+06 - - - 1.8885 - 1.837 0.307 - 265.7 1 2 0 0.0017 8 0 0 0 1.96E+08 1.82E+08 - - - 3.1421 0.9559 230117_WJC_METTL3_WT_vs_EV_F03.11633.11633.2 6.24 12-Jun K.ELITLAK.C "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 786.4851 2.46 19370 11633 2 786.487057 394.2498 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 6.1 2736.3 - 548754 - - - 2.4819 - 1.221 0.001 - 104 1 2 0 0.002 7 0 0 0 1.06E+08 4.30E+07 - - - -0.3196 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.11635.11635.2 0.0126 20-Jul K.VLFSSNGGVVK[136.11].G "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 1113.6274 1.27 19371 11635 2 1113.630918 557.821 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.72 2736.5 - 174397 - - - 3.1959 - 1.376 0.421 - 93.1 1 2 0 0.0036 11 0 0 0 1.09E+07 8.57E+06 - - - 3.0128 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.11637.11637.2 0.00274 14-Sep K.MVSAAFMK.K "sp|P25205|MCM3_HUMAN,tr|Q7Z6P5|Q7Z6P5_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 4 883.4296 2.71 19372 11637 2 883.430563 442.7221 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 8.5 2736.7 - 1.18E+06 - - - 1.1116 - 1.478 0.365 - 286.3 1 2 0 0.001 8 0 0 0 5.14E+07 1.90E+07 - - - 2.9149 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.11638.11638.2 1.17 14-Aug R.FGPLASVK.L "sp|O15042|SR140_HUMAN,tr|E7EW00|E7EW00_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H0Y8D9|H0Y8D9_HUMAN" 4 817.4698 0.15 19373 11638 2 817.470787 409.7422 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 8.75 2736.8 - 578076 - - - 1.2196 - 1.494 0.277 - 163.2 1 2 0 0.001 8 0 0 0 1.19E+08 7.94E+08 - - - 2.2974 1 230117_WJC_METTL3_WT_vs_EV_F03.11644.11644.3 2.89E-11 17/84 K.DHTPSQELALTQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2270.0411 999 19375 11644 3 2270.046986 757.6876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2737.6 - 114656 - - - 2.5942 - 3.737 0.679 - 275.1 1 2 0 0.0059 22 0 0 0 5.01E+06 0.00E+00 - - - 9.234 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.11660.11660.2 0.109 14-Jul R.LVSLIGSK.T "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 815.5117 2 19379 11660 2 815.513362 408.7631 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 2739.9 - 304878 - - - 2.0944 - 1.621 0.229 - 109.4 1 2 0 0.0017 8 0 0 0 6.82E+07 3.41E+07 - - - 2.1887 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.11664.11664.2 0.152 14-Sep R.LLGQIVDR[166.11].C sp|Q96I24|FUBP3_HUMAN 1 922.5475 1.47 19381 11664 2 922.549032 462.281 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2740.5 - 4.94E+06 - - - 1.6216 - 1.728 0.19 - 258.1 1 2 0 0.0015 8 0 0 0 1.03E+09 7.01E+08 - - - 2.0935 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.11665.11665.2 0.0135 16-Sep K.NDLAVVDVR[166.11].L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1009.5432 0.75 19382 11665 2 1009.545066 505.7789 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.21 2740.6 - 403159 - - - 1.8692 - 1.679 0.312 - 343.9 1 2 0 0.0019 9 0 0 0 1.33E+07 1.78E+07 - - - 2.844 0.9677 230117_WJC_METTL3_WT_vs_EV_F03.11676.11676.2 0.105 20-Jun K.HFSGLEEAVYR.N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1306.6306 3.63 19388 11676 2 1306.636439 654.3226 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 2742 - 142705 - - - 4.4687 - 1.292 0.137 - 58 1 2 0 0.0058 11 0 0 0 5.06E+06 1.39E+06 - - - 0.7441 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.11681.11681.2 0.0216 14-Sep R.LLGQIVDR.C sp|Q96I24|FUBP3_HUMAN 1 912.5393 1.47 19392 11681 2 912.541787 457.2769 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2742.6 - 1.67E+07 - - - 2.7626 - 1.593 0.247 - 209.2 1 2 0 0.0025 8 0 0 0 1.03E+09 7.01E+08 - - - 2.2688 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.11686.11686.2 0.049 20-Jul K.LLAETVAPAVR[166.11].G "sp|Q9BSJ8|ESYT1_HUMAN,tr|F8VZB1|F8VZB1_HUMAN" 2 1148.6793 0.26 19394 11686 2 1148.679358 575.3469 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6 2743.2 - 264356 - - - 0.0688 - 1.603 0.283 - 125.8 1 2 0 0.0001 11 0 0 0 4.29E+06 1.66E+07 - - - 2.4078 0.9967 230117_WJC_METTL3_WT_vs_EV_F03.11696.11696.2 0.247 12-May K.YVMVVYK.R "sp|Q9BPX3|CND3_HUMAN,tr|D6RA93|D6RA93_HUMAN" 2 900.4779 2.18 19397 11696 2 900.480797 451.2462 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 8.5 2744.6 - 460426 - - - 3.205 - 1.215 0.306 - 79.5 1 2 0 0.0029 7 0 0 0 2.17E+07 9.98E+06 - - - 1.9173 0.9043 230117_WJC_METTL3_WT_vs_EV_F03.11697.11697.2 0.0769 16-Apr K.SC[160.03]AHDWVYE.- "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 3 1165.4499 - 19398 11697 2 1165.453461 583.7322 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 4.71 2744.8 - 37120.8 - - - 3.0907 - 0.863 0.104 - 44.4 1 2 0 0.0036 9 0 0 0 - - - - - -0.6183 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.11698.11698.2 0.139 14-Sep R.LGMGLVSR.S "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 831.4637 1.58 19399 11698 2 831.465721 416.7391 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 9.75 2744.8 - 1.28E+06 - - - 2.4812 - 2.128 0.299 - 219.5 1 2 0 0.0021 8 0 0 0 5.63E+07 3.55E+07 - - - 3.5264 1 230117_WJC_METTL3_WT_vs_EV_F03.11714.11714.3 1.42E-08 15/68 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 2.41 19408 11714 3 2070.872264 691.296 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2746.9 - 285389 - - - 2.8838 - 3.082 0.706 - 222.9 1 2 0 0.006 18 0 0 0 8.84E+06 3.67E+06 - - - 9.2124 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.11721.11721.2 0.000747 18-Sep K.FGEVVDC[160.03]TIK.M "sp|Q99729|ROAA_HUMAN,sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 13 1166.5642 0.67 19410 11721 2 1166.56743 584.2894 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 4.37 2748 - 91949.6 - - - 2.8022 - 1.843 0.417 - 254.6 1 2 0 0.0033 10 0 0 0 1.86E+06 2.76E+06 - - - 3.8265 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.11722.11722.2 0.00694 20-Sep K.LLAETVAPAVR.G "sp|Q9BSJ8|ESYT1_HUMAN,tr|F8VZB1|F8VZB1_HUMAN" 2 1138.671 0.3 19411 11722 2 1138.676054 570.3428 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6 2748.1 - 252757 - - - 4.4306 - 1.789 0.427 - 275.1 1 2 0 0.005 11 0 0 0 4.29E+06 1.43E+07 - - - 3.7668 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.11729.11729.3 7.14E-06 Dec-68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 2.41 19413 11729 3 2078.888738 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2749.2 - 101263 - - - 3.9666 - 1.881 0.604 - 118.5 1 2 0 0.0082 18 0 0 0 8.84E+06 3.67E+06 - - - 6.845 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.11744.11744.2 0.0147 12-Jul R.VFVVMEK.L "sp|Q15139|KPCD1_HUMAN,sp|O94806|KPCD3_HUMAN,sp|Q9BZL6|KPCD2_HUMAN,tr|M0R2Z8|M0R2Z8_HUMAN,tr|F8WBA3|F8WBA3_HUMAN" 5 850.4623 0.17 19421 11744 2 850.464324 426.2384 Serine\threonine-protein kinase D1 OS=Homo sapiens OX=9606 GN=PRKD1 PE=1 SV=2 5.97 2751.3 - 197924 - - - 2.4257 - 1.489 0.204 - 128.2 1 2 0 0.0021 7 0 0 0 1.26E+07 7.53E+07 - - - 1.8085 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.11745.11745.2 0.000862 16-Jul K.ESYSVYVYK[136.11].V "sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 10 1144.5532 1.65 19422 11745 2 1144.554135 573.2839 Histone H2B type 2-F OS=Homo sapiens OX=9606 GN=H2BC18 PE=1 SV=3 6.1 2751.4 - 119171 - - - 0.8248 - 1.522 0.439 - 154.7 1 2 0 0.0009 9 0 0 0 6.79E+06 4.10E+06 - - - 3.4983 0.9954 230117_WJC_METTL3_WT_vs_EV_F03.11752.11752.2 0.413 12-Jul R.VVVEYLR.A sp|O60645|EXOC3_HUMAN 1 876.5069 1.43 19427 11752 2 876.508819 439.2607 Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3 5.97 2752.3 - 648822 - - - 2.1859 - 1.425 0.136 - 181.6 1 2 0 0.0019 7 0 0 0 4.03E+07 2.82E+07 - - - 1.1671 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.11753.11753.2 0.0261 20-Dec R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 1.29 19428 11753 2 1166.705209 584.3584 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2752.4 - 343562 - - - 2.4856 - 2.149 0.242 - 455.7 1 2 0 0.0029 11 0 0 0 5.64E+07 4.37E+07 - - - 2.897 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.11759.11759.2 0.0882 20-Sep R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 1.29 19432 11759 2 1174.718698 588.3655 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2753.1 - 692987 - - - 1.8634 - 1.87 0.283 - 214.5 1 2 0 0.0022 11 0 0 0 5.63E+07 4.37E+07 - - - 2.8239 0.975 230117_WJC_METTL3_WT_vs_EV_F03.11761.11761.2 0.000363 16-Oct L.ASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 940.5342 1.14 19434 11761 2 940.534941 471.2744 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 2753.4 - 161927 - - - 0.8081 - 2.018 0.409 - 305.8 1 1 0 0.0008 9 0 0 0 1.94E+07 1.70E+07 - - - 4.0929 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.11764.11764.3 0.0633 17/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 0.79 19435 11764 3 1166.704218 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2753.8 - 3.45E+06 - - - 1.6362 - 2.791 0.236 - 268.2 1 2 0 0.0019 11 0 0 0 2.69E+08 3.41E+08 - - - 4.0865 0.9799 230117_WJC_METTL3_WT_vs_EV_F03.11765.11765.2 0.0213 12-Jul K.LDPVLYR.K "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 874.4913 0.94 19436 11765 2 874.493618 438.2529 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 5.84 2753.9 - 1.24E+06 - - - 2.7044 - 1.353 0.039 - 238.1 1 2 0 0.0024 7 0 0 0 1.15E+08 1.22E+08 - - - 0.2862 0.9438 230117_WJC_METTL3_WT_vs_EV_F03.11766.11766.2 0.0594 18-Nov L.LASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1053.6182 0.76 19437 11766 2 1053.6214 527.8164 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2754 - 224784 - - - 2.9944 - 2.056 0.335 - 334.6 1 1 0 0.0032 10 0 0 0 9.83E+06 1.29E+07 - - - 3.5262 1 230117_WJC_METTL3_WT_vs_EV_F03.11770.11770.2 0.00205 18-Oct K.YEELQVTVGR.H sp|P35908|K22E_HUMAN 1 1192.6088 93.99 19439 11770 2 1192.611576 597.3117 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.53 2754.6 - 123923 - - - 2.326 - 1.987 0.504 - 422.6 1 2 0 0.0028 10 0 0 0 2.89E+06 3.08E+04 - - - 4.6793 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.11775.11775.2 0.0347 16-Nov K.VGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 911.5804 2.01 19441 11775 2 911.58173 456.7975 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2755.2 - 1.10E+06 - - - 1.4557 - 2.105 0.177 - 270.8 1 2 0 0.0013 9 0 0 0 7.32E+08 3.64E+08 - - - 2.5012 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.11777.11777.2 0.395 16-Nov K.VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 919.5946 2.01 19443 11777 2 919.59633 460.8046 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2755.4 - 799745 - - - 1.878 - 1.897 0.273 - 301.8 1 2 0 0.0017 9 0 0 0 7.32E+08 3.64E+08 - - - 2.9092 0.9856 230117_WJC_METTL3_WT_vs_EV_F03.11781.11781.2 0.0734 12-Jun K.LDPVLYR[166.11].K "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 884.4995 0.94 19445 11781 2 884.500806 443.257 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 5.84 2756 - 2.83E+06 - - - 1.4505 - 1.129 0.108 - 180 1 2 0 0.0013 7 0 0 0 1.15E+08 1.23E+08 - - - 0.2227 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.11782.11782.2 1.23 12-Aug K.LEDLIVK[136.11].D "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 836.5099 1.99 19446 11782 2 836.510132 419.2622 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2756.1 - 1.29E+06 - - - 0.3132 - 1.699 0.144 - 152.2 1 2 0 0.0003 7 0 0 0 1.31E+09 6.58E+08 - - - 1.784 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.11786.11786.2 0.00239 14-Aug K.FGNVYLAR.L "sp|Q9UQB9|AURKC_HUMAN,sp|O14965|AURKA_HUMAN,sp|Q96GD4|AURKB_HUMAN,tr|A3KFJ1|A3KFJ1_HUMAN,tr|J3QR41|J3QR41_HUMAN,tr|Q5Y191|Q5Y191_HUMAN,tr|A3KFJ0|A3KFJ0_HUMAN,tr|B4DXA6|B4DXA6_HUMAN,tr|A0A0A0MSY3|A0A0A0MSY3_HUMAN,tr|J3KRJ2|J3KRJ2_HUMAN,tr|J3QLN8|J3QLN8_HUMAN,tr|Q5QPD4|Q5QPD4_HUMAN,tr|J3KTD6|J3KTD6_HUMAN,tr|J3KT86|J3KT86_HUMAN" 14 938.4974 2.35 19447 11786 2 938.500008 470.256 Aurora kinase C OS=Homo sapiens OX=9606 GN=AURKC PE=1 SV=1 8.75 2756.7 - 467147 - - - 2.7778 - 1.934 0.419 - 227 1 2 0 0.0026 8 0 0 0 1.04E+08 4.41E+07 - - - 4.1242 0.9532 230117_WJC_METTL3_WT_vs_EV_F03.11790.11790.2 5.82 12-Jun R.LLLPGTR.A sp|Q6P087|RUSD3_HUMAN 1 768.4858 1.69 19449 11790 2 768.486784 385.2502 Mitochondrial mRNA pseudouridine synthase RPUSD3 OS=Homo sapiens OX=9606 GN=RPUSD3 PE=1 SV=3 9.75 2757.2 - 632147 - - - 1.3143 - 1.182 0.03 - 132.4 6 2 0 0.001 7 0 0 0 4.45E+07 2.64E+07 - - - -0.5555 0.9076 230117_WJC_METTL3_WT_vs_EV_F03.11797.11797.2 4.7 12-May R.NLGLYVK.T "sp|Q14697|GANAB_HUMAN,tr|E9PKU7|E9PKU7_HUMAN,tr|F5H6X6|F5H6X6_HUMAN" 3 805.4698 0.24 19451 11797 2 805.470812 403.7422 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 8.59 2758.2 - 431702 - - - 1.2688 - 1.025 0.002 - 75.1 2 2 0 0.001 7 0 0 0 1.86E+07 7.68E+07 - - - -1.0008 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.11805.11805.2 1.24 12-Jul R.LGLTEIR[166.11].K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 810.4839 1.17 19454 11805 2 810.484478 406.2492 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2759.4 - 1.30E+06 - - - 0.7465 - 1.631 0.15 - 149.7 1 2 0 0.0006 7 0 0 0 9.78E+08 8.35E+08 - - - 1.6987 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.11809.11809.3 0.00946 15/40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 0.79 19455 11809 3 1174.717582 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2759.9 - 7.69E+06 - - - 0.9134 - 2.686 0.351 - 209.4 1 2 0 0.0011 11 0 0 0 2.69E+08 3.41E+08 - - - 5.2599 0.9954 230117_WJC_METTL3_WT_vs_EV_F03.11812.11812.2 0.76 12-Jul R.LGLTEIR.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 800.4756 1.17 19456 11812 2 800.476073 401.2451 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2760.4 - 3.16E+06 - - - 0.5872 - 1.633 0.074 - 140.4 1 2 0 0.0005 7 0 0 0 9.79E+08 8.36E+08 - - - 1.1413 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.11814.11814.2 0.0226 18-Jun K.LITPAVVSER[166.11].L sp|P62851|RS25_HUMAN 1 1093.6371 1.06 19458 11814 2 1093.636725 547.8258 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 6 2760.6 - 240853 - - - -0.3237 - 1.499 0.341 - 110.3 1 2 0 -0.0004 10 0 0 0 1.04E+07 9.84E+06 - - - 2.6894 0.991 230117_WJC_METTL3_WT_vs_EV_F03.11817.11817.2 0.782 12-Jun K.FLEATLR.S "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN" 2 848.4756 0.76 19459 11817 2 848.474801 425.2451 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 6 2761 - 459579 - - - -0.9452 - 1.498 0.127 - 121.1 1 2 0 -0.0008 7 0 0 0 3.55E+07 4.66E+07 - - - 1.2593 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.11852.11852.2 0.34 14-Jul K.LIEQYALR.E sp|Q9NUQ3|TXLNG_HUMAN 1 1004.5655 1.53 19471 11852 2 1004.566415 503.29 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2765.9 - 398396 - - - 0.9298 - 1.34 0.187 - 129.3 1 2 0 0.0009 8 0 0 0 3.70E+07 2.43E+07 - - - 1.3046 0.9899 230117_WJC_METTL3_WT_vs_EV_F03.11855.11855.2 0.461 14-Jul K.LIEQYALR[166.11].E sp|Q9NUQ3|TXLNG_HUMAN 1 1014.5738 1.53 19473 11855 2 1014.577581 508.2942 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2766.3 - 282318 - - - 3.775 - 1.341 0.184 - 153.3 1 2 0 0.0038 8 0 0 0 3.70E+07 2.43E+07 - - - 1.2837 0.9503 230117_WJC_METTL3_WT_vs_EV_F03.11859.11859.2 2.57 12-Jun K.LMPTQWR[166.11].T sp|Q99459|CDC5L_HUMAN 1 940.4828 1.16 19474 11859 2 940.483309 471.2487 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.75 2766.8 - 1.10E+06 - - - 0.5125 - 1.084 0.028 - 147.8 1 2 0 0.0005 7 0 0 0 4.07E+07 3.51E+07 - - - -0.4968 0.9791 230117_WJC_METTL3_WT_vs_EV_F03.11868.11868.2 0.308 12-May K.LMPTQWR.T sp|Q99459|CDC5L_HUMAN 1 930.4746 1.17 19478 11868 2 930.476212 466.2446 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.75 2768 - 864394 - - - 1.7787 - 1.01 0.126 - 108.4 1 2 0 0.0017 7 0 0 0 4.09E+07 3.51E+07 - - - 0.0026 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.11876.11876.2 0.113 12-Jul R.IGNFIVK.K "sp|Q00796|DHSO_HUMAN,tr|H0YKB3|H0YKB3_HUMAN,tr|A0A6I8PIS1|A0A6I8PIS1_HUMAN" 3 789.4749 38.91 19481 11876 2 789.475763 395.7447 Sorbitol dehydrogenase OS=Homo sapiens OX=9606 GN=SORD PE=1 SV=4 8.75 2769 - 618413 - - - 1.1248 - 1.276 0.193 - 96.6 1 2 0 0.0009 7 0 0 0 2.93E+07 7.52E+05 - - - 1.2385 0.9961 230117_WJC_METTL3_WT_vs_EV_F03.11913.11913.2 0.0272 24-Aug R.GGIGAGLGGGLC[160.03]R.R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1143.5819 0.68 19496 11913 2 1143.585804 572.7982 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2773.9 - 159377 - - - 3.4348 - 1.448 0.258 - 100.8 1 2 0 0.0039 13 0 0 0 9.93E+06 1.47E+07 - - - 1.8954 0.9589 230117_WJC_METTL3_WT_vs_EV_F03.11916.11916.2 2.17 12-Jun K.FVNLYTR.E "sp|Q15650|TRIP4_HUMAN,tr|H0YL91|H0YL91_HUMAN" 2 911.4865 1.97 19498 11916 2 911.487769 456.7505 Activating signal cointegrator 1 OS=Homo sapiens OX=9606 GN=TRIP4 PE=1 SV=4 8.75 2774.3 - 251608 - - - 1.39 - 1.109 0.022 - 83.1 1 2 0 0.0013 7 0 0 0 2.32E+07 1.17E+07 - - - -0.4691 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.11920.11920.2 0.022 16-Jun R.LITGLGVGR[166.11].E sp|Q9BQG0|MBB1A_HUMAN 1 894.5526 1.19 19499 11920 2 894.553983 448.2836 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 9.75 2774.9 - 182028 - - - 1.5225 - 1.261 0.324 - 67.5 1 2 0 0.0014 9 0 0 0 1.34E+08 1.13E+08 - - - 2.1046 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.11924.11924.2 0.0551 24-Oct R.GGIGAGLGGGLC[160.03]R[166.11].R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1153.5901 0.67 19502 11924 2 1153.592403 577.8023 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2775.3 - 422677 - - - 1.9565 - 1.764 0.132 - 229 1 2 0 0.0023 13 0 0 0 9.82E+06 1.47E+07 - - - 1.472 0.9922 230117_WJC_METTL3_WT_vs_EV_F03.11927.11927.2 0.0329 12-Jul R.FALVTPK.K sp|P49792|RBP2_HUMAN 1 774.464 0.59 19503 11927 2 774.464464 388.2393 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.75 2775.7 - 547294 - - - 0.6301 - 1.427 0.076 - 183.7 1 2 0 0.0005 7 0 0 0 5.87E+07 9.90E+07 - - - 0.7288 0.9924 230117_WJC_METTL3_WT_vs_EV_F03.11935.11935.2 0.635 12-Jul R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.84 19509 11935 2 852.485385 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2776.6 - 2.09E+06 - - - 2.0294 - 1.051 0.21 - 146.7 1 2 0 0.0017 7 0 0 0 1.90E+09 1.03E+09 - - - 0.7491 0.9012 230117_WJC_METTL3_WT_vs_EV_F03.11940.11940.2 2.4 12-Apr R.FALVTPK[136.11].K sp|P49792|RBP2_HUMAN 1 782.4782 1.07 19512 11940 2 782.479107 392.2464 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.75 2777.3 - 630278 - - - 1.1898 - 0.973 0.087 - 30.3 27 2 0 0.0009 7 0 0 0 5.49E+07 5.14E+07 - - - -1.0428 0.9955 230117_WJC_METTL3_WT_vs_EV_F03.11943.11943.2 0.0313 12-Jul R.AAYIYIR[166.11].G "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|B4DE93|B4DE93_HUMAN,tr|E9PJL9|E9PJL9_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PLC6|E9PLC6_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN" 8 878.489 4.39 19513 11943 2 878.492015 440.2518 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.63 2777.7 - 227001 - - - 3.4787 - 1.288 0.265 - 171.1 1 2 0 0.0031 7 0 0 0 1.01E+08 2.30E+07 - - - 1.7993 0.9458 230117_WJC_METTL3_WT_vs_EV_F03.11944.11944.2 0.000278 16-Oct P.PVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 979.6066 2.28 19514 11944 2 979.605876 490.8106 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 9.18 2777.8 - 155286 - - - -0.7564 - 1.903 0.425 - 251.4 1 1 0 -0.0007 9 0 0 0 4.01E+06 1.75E+06 - - - 4.0413 0.8736 230117_WJC_METTL3_WT_vs_EV_F03.11949.11949.2 0.0499 12-Jun L.GNFGEVR.L "sp|P48067|SC6A9_HUMAN,tr|J3KPA5|J3KPA5_HUMAN,tr|B7Z3A9|B7Z3A9_HUMAN,tr|B7Z589|B7Z589_HUMAN" 4 777.377 0.56 19515 11949 2 777.377457 389.6958 Sodium- and chloride-dependent glycine transporter 1 OS=Homo sapiens OX=9606 GN=SLC6A9 PE=1 SV=3 6 2778.5 - 883830 - - - 0.6496 - 1.352 0.258 - 131.9 1 1 0 0.0005 7 0 0 0 8.96E+07 1.61E+08 - - - 1.902 0.999 230117_WJC_METTL3_WT_vs_EV_F03.11957.11957.2 0.00864 20-Nov K.LATNAAVTVLR.V "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1127.6663 122.21 19521 11957 2 1127.670665 564.8404 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 9.75 2779.4 - 178504 - - - 3.9081 - 2.305 0.373 - 429.2 1 2 0 0.0044 11 0 0 0 7.37E+06 6.03E+04 - - - 4.0537 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.11983.11983.2 0.618 12-Aug K.LTELLVK[136.11].A "sp|O95470|SGPL1_HUMAN,tr|H0Y3V8|H0Y3V8_HUMAN,tr|H7BXL7|H7BXL7_HUMAN" 3 822.5306 2.69 19533 11983 2 822.53119 412.2726 Sphingosine-1-phosphate lyase 1 OS=Homo sapiens OX=9606 GN=SGPL1 PE=1 SV=3 6 2782.6 - 400780 - - - 0.7112 - 1.815 0.255 - 136.7 1 2 0 0.0006 7 0 0 0 7.38E+07 2.74E+07 - - - 2.813 0.9924 230117_WJC_METTL3_WT_vs_EV_F03.11990.11990.2 0.598 14-Aug K.ILVDALQK[136.11].F "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 15 906.563 1.04 19537 11990 2 906.564192 454.2888 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 5.84 2783.4 - 1.24E+06 - - - 1.3502 - 1.431 0.073 - 177.7 1 2 0 0.0012 8 0 0 0 6.21E+07 6.00E+07 - - - 0.6606 0.9965 230117_WJC_METTL3_WT_vs_EV_F03.11993.11993.2 0.378 14-Sep R.ALLGPALK.D sp|P35250|RFC2_HUMAN 1 781.5062 1.91 19538 11993 2 781.505854 391.7604 Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3 8.8 2783.8 - 1.93E+06 - - - -0.4107 - 1.55 0.192 - 257.6 1 2 0 -0.0003 8 0 0 0 1.04E+08 5.47E+07 - - - 1.7808 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.12001.12001.2 0.0191 12-Aug K.VPVNLLR[166.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 819.5206 1.17 19542 12001 2 819.520796 410.7676 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2784.8 - 661125 - - - 0.2477 - 1.539 0.361 - 338.3 1 2 0 0.0002 7 0 0 0 1.48E+08 1.26E+08 - - - 3.0734 0.9869 230117_WJC_METTL3_WT_vs_EV_F03.12003.12003.2 0.439 12-Jun K.VPVNLLR.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 809.5123 1.17 19543 12003 2 809.511721 405.7634 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2785 - 537866 - - - -0.7437 - 1.236 0.157 - 123.5 1 2 0 -0.0006 7 0 0 0 1.48E+08 1.26E+08 - - - 0.8718 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.12008.12008.2 0.464 12-Sep K.LTELLVK.A "sp|O95470|SGPL1_HUMAN,tr|H0Y3V8|H0Y3V8_HUMAN,tr|H7BXL7|H7BXL7_HUMAN" 3 814.5164 2.7 19546 12008 2 814.516109 408.2655 Sphingosine-1-phosphate lyase 1 OS=Homo sapiens OX=9606 GN=SGPL1 PE=1 SV=3 6 2785.6 - 722147 - - - -0.3634 - 1.775 0.166 - 200.1 1 2 0 -0.0003 7 0 0 0 7.40E+07 2.74E+07 - - - 2.0851 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.12011.12011.2 0.00793 13/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 19547 12011 2 1302.609552 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2786 - 4.36E+06 - - - 0.2733 - 2.266 0.462 - 337.4 1 2 0 0.0004 13 0 0 0 1.76E+09 0.00E+00 - - - 4.5527 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.12018.12018.2 5.50E-05 20-Oct R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 6592.55 19550 12018 2 1201.609024 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2786.9 - 974750 - - - -0.094 - 1.907 0.483 - 109.7 1 2 0 -0.0001 11 0 0 0 6.69E+09 1.01E+06 - - - 4.3547 0.9946 230117_WJC_METTL3_WT_vs_EV_F03.12028.12028.2 0.0566 12-Jul K.IDPLLPK.E sp|Q9BYD6|RM01_HUMAN 1 794.4902 2.66 19553 12028 2 794.489493 398.2524 "39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2" 5.84 2788.2 - 1.39E+06 - - - -0.8786 - 1.222 0.268 - 135.7 1 2 0 -0.0007 7 0 0 0 2.51E+08 9.44E+07 - - - 1.6555 0.975 230117_WJC_METTL3_WT_vs_EV_F03.12037.12037.2 1.91 12-Jul K.IDPLLPK[136.11].E sp|Q9BYD6|RM01_HUMAN 1 802.5044 2.63 19555 12037 2 802.503605 402.2595 "39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2" 5.84 2789.5 - 1.57E+06 - - - -0.9794 - 1.205 0.137 - 115.2 2 2 0 -0.0008 7 0 0 0 2.49E+08 9.44E+07 - - - 0.509 0.9883 230117_WJC_METTL3_WT_vs_EV_F03.12061.12061.2 0.817 12-Jun K.KWDILGK.S sp|Q86YR7|MF2L2_HUMAN 1 858.4963 93.31 19564 12061 2 858.497118 430.2554 Probable guanine nucleotide exchange factor MCF2L2 OS=Homo sapiens OX=9606 GN=MCF2L2 PE=2 SV=3 8.59 2792.8 - 2.09E+06 - - - 0.9074 - 1.027 0.171 - 130.1 1 2 0 0.0008 7 0 0 0 9.31E+08 9.98E+06 - - - 0.3882 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.12063.12063.3 0.333 Dec-40 R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 2336.57 19566 12063 3 1201.608688 401.5437 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2793 - 2.24E+06 - - - -0.3737 - 2.032 0.248 - 199.3 1 2 0 -0.0004 11 0 0 0 3.96E+08 1.70E+05 - - - 3.319 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.12071.12071.2 0.0135 12-Aug R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.44 19568 12071 2 844.469155 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2794.1 - 1.88E+07 - - - -0.3553 - 1.435 0.274 - 191.9 1 2 0 -0.0003 7 0 0 0 1.03E+10 7.13E+09 - - - 2.209 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.12076.12076.2 0.444 14-Aug R.TFGVSPLR.R sp|Q5T750|XP32_HUMAN 1 875.4865 22.1 19571 12076 2 875.487422 438.7505 Skin-specific protein 32 OS=Homo sapiens OX=9606 GN=XP32 PE=1 SV=1 9.41 2794.7 - 785681 - - - 1.0508 - 1.17 0.24 - 144.3 1 2 0 0.0009 8 0 0 0 8.92E+07 4.04E+06 - - - 1.2869 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.12078.12078.2 0.476 14-Jul K.ILFTEATR.L "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 949.5233 1.89 19572 12078 2 949.523511 475.7689 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 6 2794.9 - 1.27E+06 - - - 0.2412 - 1.449 0.35 - 152.7 1 2 0 0.0002 8 0 0 0 4.54E+07 2.40E+07 - - - 2.7446 0.875 230117_WJC_METTL3_WT_vs_EV_F03.12080.12080.2 0.0414 14-Sep R.LLASTLVH.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 852.5069 - 19574 12080 2 852.50648 427.2607 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.74 2795 - 1.70E+07 - - - -0.4962 - 1.548 0.288 - 232.1 1 1 0 -0.0004 8 0 0 0 - - - - - 2.4859 0.8487 230117_WJC_METTL3_WT_vs_EV_F03.12081.12081.2 0.00429 18-Aug R.LVHPGVAEVV.F "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1018.5811 - 19575 12081 2 1018.579302 510.2978 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.24 2795.2 - 253573 - - - -1.7956 - 1.682 0.371 - 152.4 1 1 0 -0.0018 10 0 0 0 - - - - - 3.2321 0.9793 230117_WJC_METTL3_WT_vs_EV_F03.12088.12088.2 1.65 12-Jun K.GLVLMSR[166.11].A "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 16 784.4505 1.09 19577 12088 2 784.45118 393.2325 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 9.75 2796.2 - 2.98E+06 - - - 0.9115 - 1.355 0 - 139.8 1 2 0 0.0007 7 0 0 0 4.85E+08 4.45E+08 - - - 0.0034 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.12098.12098.2 0.437 12-Jul K.MLEYALK.Q "sp|Q13033|STRN3_HUMAN,sp|Q9NRL3|STRN4_HUMAN,sp|O43815|STRN_HUMAN,tr|M0R0P4|M0R0P4_HUMAN,tr|G3V3G7|G3V3G7_HUMAN,tr|F5GYK2|F5GYK2_HUMAN,tr|M0R2A7|M0R2A7_HUMAN,tr|M0QYS2|M0QYS2_HUMAN,tr|M0R0W8|M0R0W8_HUMAN,tr|G3V340|G3V340_HUMAN,tr|M0QXN2|M0QXN2_HUMAN" 11 866.4572 2.71 19579 12098 2 866.457854 434.2359 Striatin-3 OS=Homo sapiens OX=9606 GN=STRN3 PE=1 SV=3 5.75 2797.7 - 1.04E+06 - - - 0.7825 - 1.492 0.25 - 177.6 1 2 0 0.0007 7 0 0 0 4.23E+07 1.56E+07 - - - 2.1551 0.9906 230117_WJC_METTL3_WT_vs_EV_F03.12110.12110.2 2.7 12-Jul K.IPVIIER.Y "sp|A6NCE7|MP3B2_HUMAN,sp|Q9GZQ8|MLP3B_HUMAN,sp|Q9H492|MLP3A_HUMAN,tr|H3BTL1|H3BTL1_HUMAN" 4 838.5276 1.28 19585 12110 2 838.528398 420.2711 Microtubule-associated proteins 1A\1B light chain 3 beta 2 OS=Homo sapiens OX=9606 GN=MAP1LC3B2 PE=2 SV=1 6 2799.3 - 878403 - - - 0.9052 - 1.488 0.033 - 165.9 1 2 0 0.0008 7 0 0 0 4.58E+07 3.58E+07 - - - 0.5438 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.12112.12112.2 0.00056 16-Jul K.LVPVGYGIK[136.11].K sp|P24534|EF1B_HUMAN 1 952.5837 0.72 19586 12112 2 952.583432 477.2991 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2799.5 - 1.52E+06 - - - -0.2855 - 1.528 0.443 - 148.3 1 2 0 -0.0003 9 0 0 0 1.11E+09 1.53E+09 - - - 3.5395 0.8731 230117_WJC_METTL3_WT_vs_EV_F03.12114.12114.2 0.248 14-Jun R.LLEEGVLR.Q "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 927.5389 2.12 19587 12114 2 927.536349 464.7767 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 2799.7 - 548177 - - - -2.7848 - 1.165 0.083 - 85.8 1 2 0 -0.0026 8 0 0 0 1.17E+08 5.54E+07 - - - 0.1138 0.9849 230117_WJC_METTL3_WT_vs_EV_F03.12116.12116.2 0.0274 14-Jul R.VFVSPLAK[136.11].K "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 867.5309 0.74 19588 12116 2 867.529831 434.7727 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 8.72 2799.9 - 1.42E+06 - - - -1.2783 - 1.342 0.148 - 150.9 1 2 0 -0.0011 8 0 0 0 2.72E+08 3.68E+08 - - - 1.021 0.9278 230117_WJC_METTL3_WT_vs_EV_F03.12118.12118.2 0.302 12-Jul R.ILLYAC[160.03]R.N "sp|P36954|RPB9_HUMAN,tr|K7EKS1|K7EKS1_HUMAN" 2 907.495 1.23 19589 12118 2 907.492066 454.7548 DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1 8.22 2800.1 - 355790 - - - -3.1879 - 1.378 0.089 - 166.5 1 2 0 -0.0029 7 0 0 0 8.86E+07 7.21E+07 - - - 0.7134 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.12120.12120.2 0.0353 16-Sep R.NVIEAVYSR[166.11].L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1059.5588 1.44 19590 12120 2 1059.559551 530.7867 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 2800.4 - 514339 - - - 0.6814 - 1.625 0.243 - 234.3 1 2 0 0.0007 9 0 0 0 6.31E+07 4.38E+07 - - - 2.2402 0.985 230117_WJC_METTL3_WT_vs_EV_F03.12123.12123.2 0.641 12-Jul K.LFVIAQK.L sp|Q9Y3A2|UTP11_HUMAN 1 817.5062 5 19592 12123 2 817.504568 409.7604 Probable U3 small nucleolar RNA-associated protein 11 OS=Homo sapiens OX=9606 GN=UTP11 PE=1 SV=2 8.75 2800.7 - 1.26E+06 - - - -1.9657 - 1.435 0.161 - 135.6 1 2 0 -0.0016 7 0 0 0 1.50E+08 2.99E+07 - - - 1.374 0.9872 230117_WJC_METTL3_WT_vs_EV_F03.12149.12149.2 0.085 12-Jul R.ILLYAC[160.03]R[166.11].N "sp|P36954|RPB9_HUMAN,tr|K7EKS1|K7EKS1_HUMAN" 2 917.5032 1.14 19600 12149 2 917.501611 459.7589 DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1 8.22 2804.3 - 1.77E+06 - - - -1.7635 - 1.393 0.177 - 185 1 2 0 -0.0016 7 0 0 0 7.82E+07 6.86E+07 - - - 1.3981 0.9872 230117_WJC_METTL3_WT_vs_EV_F03.12152.12152.2 0.107 12-Jul R.FAAVIMR.L "sp|Q6SJ96|TBPL2_HUMAN,sp|P20226|TBP_HUMAN,tr|Q7Z6S5|Q7Z6S5_HUMAN,tr|A0A1B0GVC6|A0A1B0GVC6_HUMAN,tr|Q32MN6|Q32MN6_HUMAN" 5 806.4473 1.99 19601 12152 2 806.450793 404.2309 TATA box-binding protein-like 2 OS=Homo sapiens OX=9606 GN=TBPL2 PE=2 SV=1 9.75 2804.7 - 2.00E+06 - - - 4.3561 - 1.494 0.167 - 138.9 2 2 0 0.0035 7 0 0 0 8.35E+07 4.20E+07 - - - 1.4109 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.12166.12166.2 0.0437 16-Sep K.LVPVGYGIK.K sp|P24534|EF1B_HUMAN 1 944.5695 0.72 19607 12166 2 944.56913 473.292 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2806.6 - 1.29E+07 - - - -0.3959 - 1.674 0.362 - 297.1 1 2 0 -0.0004 9 0 0 0 1.10E+09 1.53E+09 - - - 3.2052 0.9967 230117_WJC_METTL3_WT_vs_EV_F03.12184.12184.2 0.0294 12-Aug R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.37 19612 12184 2 852.483259 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2809.1 - 4.31E+07 - - - -0.4645 - 1.24 0.289 - 194.6 1 2 0 -0.0004 7 0 0 0 8.36E+09 6.10E+09 - - - 1.857 0.9812 230117_WJC_METTL3_WT_vs_EV_F03.12194.12194.2 0.0121 12-May K.LSIVPVR[166.11].R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 792.5097 0.87 19615 12194 2 792.509131 397.2621 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2810.5 - 3.16E+07 - - - -0.7104 - 1.32 0.091 - 85.2 1 2 0 -0.0006 7 0 0 0 2.42E+09 2.77E+09 - - - 0.5926 0.9947 230117_WJC_METTL3_WT_vs_EV_F03.12217.12217.2 0.0996 14-Jul K.TPVIVTLK[136.11].E "sp|Q9Y4L1|HYOU1_HUMAN,tr|A0A087WWI4|A0A087WWI4_HUMAN,tr|K7EQK2|K7EQK2_HUMAN,tr|A0A087WW13|A0A087WW13_HUMAN,tr|Q9BST8|Q9BST8_HUMAN,tr|J3KTF1|J3KTF1_HUMAN,tr|A0A494C039|A0A494C039_HUMAN,tr|J3QL06|J3QL06_HUMAN,tr|A0A087X214|A0A087X214_HUMAN,tr|A0A087X054|A0A087X054_HUMAN,tr|E9PJ21|E9PJ21_HUMAN,tr|J3QLE9|J3QLE9_HUMAN,tr|J3QQH7|J3QQH7_HUMAN" 13 877.5728 1.16 19625 12217 2 877.572854 439.7937 Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1 8.41 2813.6 - 219285 - - - 0.0558 - 1.284 0.191 - 86.9 1 2 0 0.0001 8 0 0 0 1.13E+07 9.72E+06 - - - 1.2056 0.9962 230117_WJC_METTL3_WT_vs_EV_F03.12220.12220.2 0.416 12-Jul K.LSIVPVR.R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 782.5014 0.87 19626 12220 2 782.501293 392.258 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2814 - 5.00E+07 - - - -0.1674 - 1.524 0.163 - 192.8 1 2 0 -0.0001 7 0 0 0 2.42E+09 2.77E+09 - - - 1.5799 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.12238.12238.2 0.0025 16-Jul K.VLEGMEVVR[166.11].K "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1040.5564 0.12 19631 12238 2 1040.554572 521.2855 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.53 2816.7 - 284991 - - - -1.7433 - 1.457 0.352 - 152.3 1 2 0 -0.0018 9 0 0 0 5.86E+06 5.00E+07 - - - 2.7292 0.999 230117_WJC_METTL3_WT_vs_EV_F03.12247.12247.2 0.0292 12-Jul K.YLYEIAR.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 926.4862 45.78 19635 12247 2 926.486311 464.2504 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6 2817.8 - 1.11E+07 - - - 0.1543 - 1.39 0.356 - 185.7 1 2 0 0.0001 7 0 0 0 7.36E+08 1.61E+07 - - - 2.7138 0.9943 230117_WJC_METTL3_WT_vs_EV_F03.12271.12271.2 1.31 14-Jul K.IIGDTFVK.L sp|P49915|GUAA_HUMAN 1 891.5066 2.55 19645 12271 2 891.506861 446.7606 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.84 2821.1 - 3.25E+06 - - - 0.3275 - 1.293 0.167 - 111.2 1 2 0 0.0003 8 0 0 0 2.78E+08 1.09E+08 - - - 1.0494 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.12299.12299.2 0.00669 12-Jul R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.44 19658 12299 2 844.470351 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2824.6 - 4.81E+07 - - - 1.061 - 1.497 0.325 - 144.6 1 2 0 0.0009 7 0 0 0 1.03E+10 7.13E+09 - - - 2.7196 0.9062 230117_WJC_METTL3_WT_vs_EV_F03.12329.12329.2 0.0763 12-Jul F.ILEVYYK[136.11].S sp|A8MTT3|CEBOS_HUMAN 1 934.5255 5.04 19675 12329 2 934.526481 468.27 Protein CEBPZOS OS=Homo sapiens OX=9606 GN=CEBPZOS PE=1 SV=2 6 2828.3 - 559469 - - - 1.0283 - 1.453 0.259 - 132.5 1 1 0 0.001 7 0 0 0 1.44E+08 2.86E+07 - - - 2.1375 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.12356.12356.2 0.00322 20-Jul R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 40.89 19690 12356 2 1201.61092 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2831.7 - 223092 - - - 1.4838 - 1.869 0.369 - 78.3 1 2 0 0.0018 11 0 0 0 2.10E+07 5.13E+05 - - - 3.4577 0.9751 230117_WJC_METTL3_WT_vs_EV_F03.12361.12361.2 0.0517 16-Oct R.PLISVYSEK[136.11].G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1042.579 0.78 19693 12361 2 1042.580331 522.2968 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.42 2832.3 - 571503 - - - 1.2651 - 2.04 0.388 - 404.9 1 1 0 0.0013 9 0 0 0 4.59E+07 5.90E+07 - - - 3.969 0.9801 230117_WJC_METTL3_WT_vs_EV_F03.12371.12371.2 3.48 14-Jun K.LIGEYGLR.N "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 919.5127 0.8 19696 12371 2 919.514683 460.7636 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 2833.7 - 558841 - - - 2.1381 - 1.22 0.063 - 72.6 1 2 0 0.002 8 0 0 0 2.24E+09 2.78E+09 - - - 0.1054 0.9831 230117_WJC_METTL3_WT_vs_EV_F03.12378.12378.2 1.76 12-Jul R.LLSVNIR.V sp|P07814|SYEP_HUMAN 1 813.5072 1.44 19698 12378 2 813.506926 407.7609 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 9.75 2834.7 - 819339 - - - -0.3835 - 1.29 0.092 - 120.8 1 2 0 -0.0003 7 0 0 0 2.14E+08 1.49E+08 - - - 0.5273 0.9945 230117_WJC_METTL3_WT_vs_EV_F03.12386.12386.2 1.33 16-Jul R.LLGTLAVSR[166.11].G "sp|Q96MI6|PPM1M_HUMAN,tr|H7C3K4|H7C3K4_HUMAN,tr|H7C3S3|H7C3S3_HUMAN" 3 938.5788 1.38 19700 12386 2 938.580971 470.2967 Protein phosphatase 1M OS=Homo sapiens OX=9606 GN=PPM1M PE=2 SV=2 9.75 2835.8 - 235962 - - - 2.2747 - 1.374 0.15 - 88.7 1 2 0 0.0021 9 0 0 0 1.07E+07 7.73E+06 - - - 1.0674 0.9607 230117_WJC_METTL3_WT_vs_EV_F03.12388.12388.2 0.00267 16-Sep R.PLISVYSEK.G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1034.5648 0.79 19701 12388 2 1034.567152 518.2897 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.42 2836.1 - 968401 - - - 2.2618 - 1.63 0.411 - 298.8 1 1 0 0.0023 9 0 0 0 4.60E+07 5.85E+07 - - - 3.4894 0.9951 230117_WJC_METTL3_WT_vs_EV_F03.12390.12390.2 0.127 12-May K.VLPIIQR.W "sp|Q9BYW2|SETD2_HUMAN,tr|H7C3H4|H7C3H4_HUMAN,tr|A0A1W2PPX9|A0A1W2PPX9_HUMAN" 3 837.5436 1.81 19702 12390 2 837.545058 419.7791 Histone-lysine N-methyltransferase SETD2 OS=Homo sapiens OX=9606 GN=SETD2 PE=1 SV=3 9.72 2836.3 - 370634 - - - 1.7133 - 1.107 0.223 - 65.5 1 2 0 0.0014 7 0 0 0 2.77E+07 1.53E+07 - - - 1.0097 0.995 230117_WJC_METTL3_WT_vs_EV_F03.12413.12413.2 0.0181 12-Jul R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.33 19710 12413 2 852.482852 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2839.5 - 1.45E+06 - - - -0.942 - 1.337 0.242 - 144.8 1 2 0 -0.0008 7 0 0 0 8.12E+09 6.10E+09 - - - 1.7484 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.12424.12424.2 0.000523 18-Sep K.DVNAAIATIK.T "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 8 1014.571 5.32 19713 12424 2 1014.570165 508.2928 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 5.84 2841.1 - 483099 - - - -0.7836 - 1.806 0.476 - 147.6 1 2 0 -0.0008 10 0 0 0 1.94E+07 3.65E+06 - - - 4.2065 0.9056 230117_WJC_METTL3_WT_vs_EV_F03.12431.12431.2 3.75 14-Apr K.QYFEQFGK[136.11].V "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|J3KTC1|J3KTC1_HUMAN" 7 1053.5011 1.35 19718 12431 2 1053.500184 527.7578 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6 2841.9 - 113527 - - - -0.8657 - 0.856 0.132 - 46.2 1 2 0 -0.0009 8 0 0 0 2.84E+06 2.10E+06 - - - -0.4533 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.12436.12436.2 1.33 12-Aug R.IGTFDLK[136.11].Y "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN" 2 800.4524 0.47 19721 12436 2 800.452615 401.2335 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 5.84 2842.6 - 831145 - - - 0.3248 - 1.444 0.163 - 126.6 1 2 0 0.0003 7 0 0 0 2.08E+07 4.38E+07 - - - 1.409 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.12447.12447.2 0.192 14-Jul R.EMLAAALR[166.11].T "sp|P23193|TCEA1_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 3 883.4825 2 19727 12447 2 883.48275 442.7485 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 6.1 2843.9 - 732478 - - - 0.2909 - 1.538 0.228 - 141.4 1 2 0 0.0003 8 0 0 0 7.07E+07 3.54E+07 - - - 2.0232 0.8642 230117_WJC_METTL3_WT_vs_EV_F03.12454.12454.2 5.35 12-Jun K.TC[160.03]PLLLR[166.11].V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 881.5032 1.26 19731 12454 2 881.501374 441.7589 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2844.7 - 601139 - - - -2.1044 - 1.211 0.019 - 116.6 1 2 0 -0.0019 7 0 0 0 1.20E+09 9.56E+08 - - - -0.2126 0.9876 230117_WJC_METTL3_WT_vs_EV_F03.12455.12455.2 0.2 12-Jun R.IGTFDLK.Y "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN" 2 792.4382 0.38 19732 12455 2 792.44189 397.2264 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 5.84 2844.8 - 977887 - - - 4.7133 - 1.382 0.214 - 66.4 1 2 0 0.0037 7 0 0 0 2.11E+07 5.59E+07 - - - 1.6456 0.955 230117_WJC_METTL3_WT_vs_EV_F03.12462.12462.2 2.16 12-May R.GDIQTLK[136.11].N sp|Q9HC62|SENP2_HUMAN 1 781.4425 1.05 19736 12462 2 781.443178 391.7285 Sentrin-specific protease 2 OS=Homo sapiens OX=9606 GN=SENP2 PE=1 SV=3 5.84 2845.6 - 674693 - - - 0.8433 - 1.036 0.048 - 112.3 1 2 0 0.0007 7 0 0 0 5.33E+08 5.07E+08 - - - -0.4926 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.12472.12472.2 0.0187 12-Jun K.TC[160.03]PLLLR.V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 871.495 1.25 19741 12472 2 871.495502 436.7548 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2846.9 - 1.34E+06 - - - 0.6231 - 1.378 0.358 - 163.9 1 2 0 0.0005 7 0 0 0 1.20E+09 9.55E+08 - - - 2.701 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.12488.12488.2 5.68E-05 16-Aug R.LYEALTPVH.- "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1041.5495 - 19748 12488 2 1041.552088 521.782 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.24 2849 - 670097 - - - 2.4886 - 1.646 0.43 - 230.1 1 2 0 0.0026 9 0 0 0 - - - - - 3.6579 0.9745 230117_WJC_METTL3_WT_vs_EV_F03.12492.12492.2 0.357 18-Jun R.SINQPVAFVR.R "sp|Q9GZT3|SLIRP_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|H0YJI1|H0YJI1_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1129.6244 1.39 19749 12492 2 1129.628415 565.8195 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 9.47 2849.6 - 109733 - - - 3.5605 - 1.153 0.141 - 92.1 1 2 0 0.004 10 0 0 0 5.49E+06 3.95E+06 - - - 0.4786 0.9711 230117_WJC_METTL3_WT_vs_EV_F03.12495.12495.2 0.08 18-Jun R.TIAQDYGVLK.A "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1106.5972 1.32 19750 12495 2 1106.599332 554.3059 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.5 2850 - 128369 - - - 1.9492 - 1.046 0.088 - 75 1 2 0 0.0022 10 0 0 0 1.07E+07 8.10E+06 - - - -0.1842 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.12515.12515.2 0.000336 14-Sep R.LPLQDVYK[136.11].L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 982.5579 5.22 19755 12515 2 982.558568 492.2862 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2853 - 2.83E+06 - - - 0.6972 - 1.877 0.363 - 342.6 1 2 0 0.0007 8 0 0 0 2.33E+09 4.47E+08 - - - 3.621 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.12517.12517.2 0.0162 12-Jun R.WLGEPIK[136.11].A "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 849.484 0.46 19757 12517 2 849.485099 425.7493 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6 2853.2 - 1.56E+06 - - - 1.3055 - 1.254 0.316 - 149.5 1 2 0 0.0011 7 0 0 0 1.16E+09 2.52E+09 - - - 2.0918 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.12521.12521.4 5.61E-05 16/108 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 3.3 19759 12521 4 2080.025172 521.0129 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2853.7 - 553904 - - - 1.2687 - 2.541 0.45 - 86.7 1 2 0 0.0026 19 0 0 0 3.76E+07 1.14E+07 - - - 3.4575 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.12522.12522.3 0.000624 Aug-72 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 4.99 19760 12522 3 2080.027994 694.3481 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2853.8 - 84392.4 - - - 2.6255 - 1.577 0.48 - 31.5 1 2 0 0.0055 19 0 0 0 9.45E+06 1.90E+06 - - - 5.0091 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.12531.12531.2 0.0341 14-Sep K.AGLYGLPR.R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|A0A0U1RRG3|A0A0U1RRG3_HUMAN" 3 845.4759 2.37 19764 12531 2 845.47584 423.7452 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.79 2854.9 - 5.41E+06 - - - -0.1159 - 1.878 0.352 - 254.8 1 2 0 -0.0001 8 0 0 0 4.23E+08 1.78E+08 - - - 3.5415 0.9938 230117_WJC_METTL3_WT_vs_EV_F03.12543.12543.2 0.358 12-Jun R.WLGEPIK.A "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 841.4698 0.45 19767 12543 2 841.47015 421.7422 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6 2856.7 - 4.14E+06 - - - 0.4278 - 1.146 0.201 - 189.2 1 2 0 0.0004 7 0 0 0 1.15E+09 2.52E+09 - - - 0.9573 0.9921 230117_WJC_METTL3_WT_vs_EV_F03.12544.12544.2 0.395 14-Jul K.IPYTTVLR.L "sp|Q08945|SSRP1_HUMAN,tr|E9PMD4|E9PMD4_HUMAN" 2 961.5597 0.26 19768 12544 2 961.560545 481.7871 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 8.75 2856.8 - 220459 - - - 0.9131 - 1.319 0.107 - 142.6 1 2 0 0.0009 8 0 0 0 1.20E+08 4.67E+08 - - - 0.6661 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.12562.12562.2 0.00167 20-Oct R.TAAENDFVTLK.K sp|P35908|K22E_HUMAN 1 1207.6085 12.22 19776 12562 2 1207.610198 604.8115 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2859.1 - 69526 - - - 1.4326 - 1.696 0.425 - 224.7 1 2 0 0.0017 11 0 0 0 4.94E+06 4.04E+05 - - - 3.6086 0.9962 230117_WJC_METTL3_WT_vs_EV_F03.12563.12563.2 0.65 12-Jun R.VAFLVSR.L sp|Q6ICC9|RTL6_HUMAN 1 790.4701 0.74 19777 12563 2 790.47095 396.2423 Retrotransposon Gag-like protein 6 OS=Homo sapiens OX=9606 GN=RTL6 PE=2 SV=1 9.72 2859.2 - 755222 - - - 1.0449 - 1.345 0.183 - 118 2 2 0 0.0008 7 0 0 0 3.33E+07 4.49E+07 - - - 1.197 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.12568.12568.2 0.0738 12-May R.LVVFDAR[166.11].- sp|P53803|RPAB4_HUMAN 1 828.4733 1.03 19779 12568 2 828.473985 415.2439 "DNA-directed RNA polymerases I, II, and III subunit RPABC4 OS=Homo sapiens OX=9606 GN=POLR2K PE=1 SV=1" 5.84 2859.9 - 4.77E+06 - - - 0.8172 - 1.26 0.346 - 88.4 1 2 0 0.0007 7 0 0 0 3.15E+08 3.04E+08 - - - 2.3286 0.9142 230117_WJC_METTL3_WT_vs_EV_F03.12573.12573.2 0.067 14-Jun L.VDHALIAR[166.11].C sp|Q05BV3|EMAL5_HUMAN 1 903.5166 4.15 19780 12573 2 903.517018 452.7656 Echinoderm microtubule-associated protein-like 5 OS=Homo sapiens OX=9606 GN=EML5 PE=2 SV=3 6.71 2860.6 - 701341 - - - 0.4958 - 1.426 0.307 - 144.7 1 1 0 0.0004 8 0 0 0 1.75E+08 4.21E+07 - - - 2.3786 0.998 230117_WJC_METTL3_WT_vs_EV_F03.12591.12591.2 0.264 16-Aug K.AGLAPLEVR[166.11].V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 934.5475 0.66 19789 12591 2 934.547421 468.281 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.05 2862.8 - 416078 - - - -0.1231 - 1.525 0.256 - 157.9 1 2 0 -0.0001 9 0 0 0 2.24E+07 3.40E+07 - - - 2.1526 0.9935 230117_WJC_METTL3_WT_vs_EV_F03.12605.12605.2 1.24 16-Jun K.LVPVGYGIR[166.11].K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 982.5839 0.94 19793 12605 2 982.585136 492.2992 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2864.8 - 4.01E+06 - - - 1.2355 - 1.15 0.18 - 98.2 1 2 0 0.0012 9 0 0 0 7.86E+08 8.36E+08 - - - 0.7744 0.8775 230117_WJC_METTL3_WT_vs_EV_F03.12617.12617.2 0.114 16-Jul K.IGPLGLSPK[136.11].K sp|P30050|RL12_HUMAN 1 888.5524 1.62 19797 12617 2 888.548553 445.2835 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2866.4 - 4.85E+06 - - - -4.3329 - 1.27 0.146 - 111.6 1 2 0 -0.0039 9 0 0 0 1.22E+10 7.55E+09 - - - 0.8096 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.12622.12622.2 0.0003 16-Nov K.IGPLGLSPK.K sp|P30050|RL12_HUMAN 1 880.5382 1.62 19799 12622 2 880.538536 441.2764 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2867.1 - 4.92E+06 - - - 0.3782 - 1.855 0.319 - 316.7 1 2 0 0.0003 9 0 0 0 1.22E+10 7.57E+09 - - - 3.1846 0.9969 230117_WJC_METTL3_WT_vs_EV_F03.12623.12623.2 0.0271 12-Aug R.FAAFIDK.V "sp|Q14533|KRT81_HUMAN,sp|P78386|KRT85_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|U3KPR1|U3KPR1_HUMAN" 6 810.4276 66.78 19800 12623 2 810.428092 406.2211 "Keratin, type II cuticular Hb1 OS=Homo sapiens OX=9606 GN=KRT81 PE=1 SV=3" 5.84 2867.1 - 1.70E+06 - - - 0.6194 - 1.578 0.131 - 161.8 1 2 0 0.0005 7 0 0 0 1.00E+08 1.50E+06 - - - 1.4538 0.9961 230117_WJC_METTL3_WT_vs_EV_F03.12627.12627.2 0.204 12-Jul K.FLEPTLR.L "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 874.4913 1.03 19801 12627 2 874.492334 438.2529 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 2867.7 - 5.11E+06 - - - 1.2361 - 1.335 0.181 - 235.5 2 2 0 0.0011 7 0 0 0 3.87E+08 3.75E+08 - - - 1.1586 0.9939 230117_WJC_METTL3_WT_vs_EV_F03.12632.12632.2 0.838 12-Jun R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 142.37 19803 12632 2 776.381945 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2868.4 - 825807 - - - 0.3117 - 1.313 0.148 - 120.9 1 2 0 0.0002 7 0 0 0 1.16E+09 8.14E+06 - - - 0.9969 0.917 230117_WJC_METTL3_WT_vs_EV_F03.12637.12637.2 0.939 14-Jun R.ALTLGLAK.R sp|Q9BUH6|PAXX_HUMAN 1 785.5011 0.97 19805 12637 2 785.50058 393.7578 Protein PAXX OS=Homo sapiens OX=9606 GN=PAXX PE=1 SV=2 8.8 2869 - 617224 - - - -0.6493 - 1.253 0.013 - 74.5 4 2 0 -0.0005 8 0 0 0 3.56E+07 3.68E+07 - - - -0.4519 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.12638.12638.2 0.518 12-Jul R.LAILYAK.R "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 790.4953 1.15 19806 12638 2 790.495367 396.2549 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 8.59 2869.1 - 453513 - - - 0.1151 - 1.747 0.126 - 149.8 1 2 0 0.0001 7 0 0 0 2.66E+08 2.32E+08 - - - 1.7393 0.9869 230117_WJC_METTL3_WT_vs_EV_F03.12646.12646.2 0.691 16-May K.LVPVGYGIR.K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 972.5757 0.94 19808 12646 2 972.575066 487.2951 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2870.2 - 1.45E+07 - - - -0.6025 - 1.113 0.197 - 77.9 1 2 0 -0.0006 9 0 0 0 7.89E+08 8.37E+08 - - - 0.8056 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.12658.12658.2 0.723 12-Sep R.TLQVLIK.Q "sp|Q7Z3B4|NUP54_HUMAN,sp|P35219|CAH8_HUMAN" 2 813.5324 2.25 19812 12658 2 813.532565 407.7735 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.41 2871.9 - 1.78E+06 - - - 0.2151 - 1.832 0.189 - 284.9 1 2 0 0.0002 7 0 0 0 2.00E+08 8.90E+07 - - - 2.3552 0.9882 230117_WJC_METTL3_WT_vs_EV_F03.12693.12693.2 1 12-Aug K.TAISLLR[166.11].N sp|Q99959|PKP2_HUMAN 1 782.489 1.09 19819 12693 2 782.490581 392.2518 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 9.41 2877.1 - 1.65E+06 - - - 2.0729 - 1.208 0.109 - 188.5 1 2 0 0.0016 7 0 0 0 9.81E+07 8.98E+07 - - - 0.4443 0.9731 230117_WJC_METTL3_WT_vs_EV_F03.12697.12697.2 0.173 14-Aug K.TALLGLTK[136.11].T sp|Q9BTZ2|DHRS4_HUMAN 1 823.5259 0.95 19821 12697 2 823.529192 412.7702 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 8.41 2877.5 - 2.45E+06 - - - 4.0533 - 1.31 0.111 - 191.5 1 2 0 0.0033 8 0 0 0 7.16E+08 7.52E+08 - - - 0.6742 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.12709.12709.2 0.00177 18-Jul R.LIAAATSVLK[136.11].T "sp|P24863|CCNC_HUMAN,tr|E5RFX8|E5RFX8_HUMAN,tr|E5RI39|E5RI39_HUMAN,tr|J3KP90|J3KP90_HUMAN,tr|E5RFK5|E5RFK5_HUMAN,tr|G5E954|G5E954_HUMAN,tr|H0YBQ5|H0YBQ5_HUMAN" 7 993.6314 1.22 19825 12709 2 993.631181 497.823 Cyclin-C OS=Homo sapiens OX=9606 GN=CCNC PE=1 SV=2 8.75 2879.1 - 240786 - - - -0.2023 - 1.415 0.386 - 73.6 1 2 0 -0.0002 10 0 0 0 1.29E+07 1.05E+07 - - - 2.8609 0.9818 230117_WJC_METTL3_WT_vs_EV_F03.12721.12721.2 0.0423 14-Aug K.FGELVMTK.E "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 923.4786 3 19828 12721 2 923.477073 462.7466 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6 2880.9 - 729837 - - - -1.6968 - 1.159 0.216 - 174.2 1 2 0 -0.0016 8 0 0 0 1.61E+08 5.35E+07 - - - 1.0809 0.9934 230117_WJC_METTL3_WT_vs_EV_F03.12725.12725.2 3.5 14-Sep R.LPVDIAYK.R sp|P15924|DESP_HUMAN 1 917.5222 5.5 19830 12725 2 917.521128 459.7684 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.83 2881.4 - 1.80E+06 - - - -1.1891 - 1.58 0.166 - 278.2 1 2 0 -0.0011 8 0 0 0 3.14E+08 5.71E+07 - - - 1.6463 0.9302 230117_WJC_METTL3_WT_vs_EV_F03.12730.12730.2 0.332 14-Oct D.IADIEALK.E "sp|Q70CQ2|UBP34_HUMAN,sp|O75792|RNH2A_HUMAN,tr|A0A2R8Y606|A0A2R8Y606_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 4 871.5015 1.72 19833 12730 2 871.501774 436.758 Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens OX=9606 GN=USP34 PE=1 SV=2 4.37 2882 - 4.45E+06 - - - 0.3328 - 2.092 0.194 - 253.2 1 1 0 0.0003 8 0 0 0 3.17E+08 1.85E+08 - - - 2.6999 0.993 230117_WJC_METTL3_WT_vs_EV_F03.12735.12735.2 0.529 20-Jun R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 999 19835 12735 2 1068.658535 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 2882.7 - 1.62E+06 - - - 3.9667 - 1.66 0.192 - 90.4 2 2 0 0.0042 11 0 0 0 6.10E+08 0.00E+00 - - - 1.6944 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.12748.12748.2 0.0141 18-Aug R.LIAAATSVLK.T "sp|P24863|CCNC_HUMAN,tr|E5RFX8|E5RFX8_HUMAN,tr|E5RI39|E5RI39_HUMAN,tr|J3KP90|J3KP90_HUMAN,tr|E5RFK5|E5RFK5_HUMAN,tr|G5E954|G5E954_HUMAN,tr|H0YBQ5|H0YBQ5_HUMAN" 7 985.6172 1.22 19841 12748 2 985.617214 493.8159 Cyclin-C OS=Homo sapiens OX=9606 GN=CCNC PE=1 SV=2 8.75 2884.2 - 374066 - - - 0.0325 - 1.403 0.372 - 105.7 1 2 0 0 10 0 0 0 1.29E+07 1.05E+07 - - - 2.7338 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.12761.12761.2 0.00949 14-Jul K.SALALAIK[136.11].V "sp|P25789|PSA4_HUMAN,tr|H0YKS0|H0YKS0_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 8 793.5153 1.46 19847 12761 2 793.514787 397.7649 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 8.47 2885.8 - 5.14E+06 - - - -0.6339 - 1.511 0.361 - 128 1 2 0 -0.0005 8 0 0 0 4.64E+08 3.17E+08 - - - 2.9521 0.9967 230117_WJC_METTL3_WT_vs_EV_F03.12763.12763.2 0.274 14-Jul K.FGELVMTK[136.11].E "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 931.4928 3.05 19848 12763 2 931.493886 466.7537 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6 2886 - 776247 - - - 1.1229 - 1.268 0.211 - 113.4 1 2 0 0.001 8 0 0 0 1.65E+08 5.41E+07 - - - 1.3152 0.9904 230117_WJC_METTL3_WT_vs_EV_F03.12772.12772.4 0.0681 15/96 T.LLLIILTDVFIISTVLR.L sp|Q8NGY0|O10X1_HUMAN 1 1941.2278 7.25 19850 12772 4 1941.231156 486.3142 Olfactory receptor 10X1 OS=Homo sapiens OX=9606 GN=OR10X1 PE=3 SV=2 5.84 2887.4 - 1.62E+06 - - - 1.7175 - 2.074 0.354 - 57.2 1 1 0 0.0033 17 0 0 0 7.70E+07 1.06E+07 - - - 2.5596 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.12792.12792.2 0.0558 18-Oct R.ISGLIYEETR[166.11].G sp|P62805|H4_HUMAN 1 1189.6218 0.69 19857 12792 2 1189.621848 595.8182 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2890.3 - 169100 - - - 0.021 - 2.322 0.351 - 302.1 1 2 0 0 10 0 0 0 7.52E+06 1.10E+07 - - - 3.985 0.9566 230117_WJC_METTL3_WT_vs_EV_F03.12800.12800.2 1.26 18-Jun R.LGPSVVGLAR[166.11].Y "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 977.5897 1.47 19860 12800 2 977.59022 489.8021 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 9.75 2891.3 - 171168 - - - 0.4961 - 1.209 0.058 - 45.9 8 2 0 0.0005 10 0 0 0 7.05E+07 4.79E+07 - - - -0.4044 0.8663 230117_WJC_METTL3_WT_vs_EV_F03.12809.12809.2 8.89 18-May R.SISLYYTGEK.G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1159.5761 0.89 19865 12809 2 1159.577265 580.7953 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 5.72 2892.5 - 117962 - - - 1.0004 - 0.877 0.054 - 44.2 5 2 0 0.0012 10 0 0 0 1.79E+06 2.00E+06 - - - -1.2391 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.12819.12819.2 0.143 20-Oct K.LIADVAPSAIR[166.11].E "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1134.6636 1.81 19870 12819 2 1134.66547 568.3391 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 5.84 2893.8 - 232341 - - - 1.6225 - 1.525 0.246 - 323.7 1 2 0 0.0018 11 0 0 0 2.96E+07 1.63E+07 - - - 1.999 0.9872 230117_WJC_METTL3_WT_vs_EV_F03.12822.12822.2 0.216 18-Jul R.SISLYYTGEK[136.11].G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1167.5903 0.89 19871 12822 2 1167.595309 584.8024 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 5.72 2894.2 - 93343.7 - - - 4.2857 - 1.224 0.239 - 105.1 1 2 0 0.005 10 0 0 0 1.79E+06 2.00E+06 - - - 1.3689 0.9947 230117_WJC_METTL3_WT_vs_EV_F03.12831.12831.2 0.379 14-Jul K.QVEELFER[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1058.5272 2.71 19876 12831 2 1058.530202 530.2709 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2895.3 - 253607 - - - 2.8407 - 1.383 0.177 - 201.3 1 2 0 0.003 8 0 0 0 2.85E+07 1.05E+07 - - - 1.3253 0.9828 230117_WJC_METTL3_WT_vs_EV_F03.12834.12834.2 0.022 14-Jul R.VIAQLEIR.Q "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|E9PLY5|E9PLY5_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A669KBB0|A0A669KBB0_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A5F9ZGX0|A0A5F9ZGX0_HUMAN" 10 940.5706 4.18 19878 12834 2 940.574369 471.2926 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.97 2895.7 - 310100 - - - 4.0433 - 1.344 0.145 - 97.2 1 2 0 0.0038 8 0 0 0 7.82E+06 1.87E+06 - - - 1.0024 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.12840.12840.2 0.601 12-Sep K.TELLGLK.E sp|Q69YU5|BWNIN_HUMAN 1 772.4695 1.54 19882 12840 2 772.472001 387.242 Protein BRAWNIN OS=Homo sapiens OX=9606 GN=BRAWNIN PE=1 SV=2 5.66 2896.4 - 1.33E+06 - - - 3.2959 - 1.513 0.176 - 365.8 1 2 0 0.0025 7 0 0 0 4.19E+07 2.73E+07 - - - 1.6522 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.12843.12843.2 0.0217 16-Oct K.IGPLGLSPK[136.11].K sp|P30050|RL12_HUMAN 1 888.5524 1.62 19884 12843 2 888.55363 445.2835 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2896.8 - 1.40E+06 - - - 1.3809 - 1.581 0.345 - 228.6 1 2 0 0.0012 9 0 0 0 1.22E+10 7.55E+09 - - - 2.914 0.9605 230117_WJC_METTL3_WT_vs_EV_F03.12845.12845.2 1.49 12-May R.EFVTAFK[136.11].K "sp|P13667|PDIA4_HUMAN,tr|A0A499FI48|A0A499FI48_HUMAN" 2 848.4524 6.4 19885 12845 2 848.454616 425.2335 Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2 6.1 2897 - 214652 - - - 2.6649 - 0.993 0.108 - 68.2 1 2 0 0.0023 7 0 0 0 2.08E+08 3.25E+07 - - - -0.1843 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.12847.12847.2 0.00282 16-Sep K.IGPLGLSPK.K sp|P30050|RL12_HUMAN 1 880.5382 1.62 19886 12847 2 880.540529 441.2764 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2897.2 - 2.55E+06 - - - 2.6416 - 1.815 0.302 - 214.3 1 2 0 0.0023 9 0 0 0 1.22E+10 7.56E+09 - - - 2.9953 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.12853.12853.4 0.00119 17/198 R.SDSPVPTAPTSGGPKPSTASAVPELATDPELEKK.L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3360.6937 999 19890 12853 4 3360.70251 841.1807 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2897.9 - 617207 - - - 2.6331 - 2.621 0.421 - 98.1 1 2 0 0.0088 34 0 0 0 1.26E+07 0.00E+00 - - - 3.1753 0.8631 230117_WJC_METTL3_WT_vs_EV_F03.12856.12856.2 0.426 12-Aug R.FGILTEK.Y "sp|Q16134|ETFD_HUMAN,tr|B4DEQ0|B4DEQ0_HUMAN,tr|A0A804HK05|A0A804HK05_HUMAN,tr|A0A804HJT7|A0A804HJT7_HUMAN,tr|A0A804HI48|A0A804HI48_HUMAN,tr|A0A804HK66|A0A804HK66_HUMAN,tr|A0A804HL81|A0A804HL81_HUMAN,tr|A0A804HJK8|A0A804HJK8_HUMAN,tr|A0A804HI73|A0A804HI73_HUMAN,tr|A0A804HL84|A0A804HL84_HUMAN" 10 806.4538 1.98 19892 12856 2 806.461498 404.2342 "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=ETFDH PE=1 SV=2" 6 2898.2 - 485632 - - - 9.5393 - 1.24 0.234 - 167.2 1 2 0 0.0077 7 0 0 0 3.13E+07 1.58E+07 - - - 1.4485 0.9928 230117_WJC_METTL3_WT_vs_EV_F03.12857.12857.2 0.138 12-Jul R.VFLQQLK.G "sp|Q13487|SNPC2_HUMAN,tr|M0QXY9|M0QXY9_HUMAN" 2 874.5276 0.06 19893 12857 2 874.530913 438.2711 snRNA-activating protein complex subunit 2 OS=Homo sapiens OX=9606 GN=SNAPC2 PE=1 SV=1 8.72 2898.3 - 228340 - - - 3.7437 - 1.352 0.209 - 119 1 2 0 0.0033 7 0 0 0 9.38E+06 1.55E+08 - - - 1.5392 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.12863.12863.2 0.382 18-Oct R.LGPSVVGLAR.Y "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 967.5815 1.47 19898 12863 2 967.584453 484.798 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 9.75 2899 - 1.00E+06 - - - 3.0881 - 2.125 0.206 - 336.9 1 2 0 0.003 10 0 0 0 7.05E+07 4.79E+07 - - - 2.6656 0.9956 230117_WJC_METTL3_WT_vs_EV_F03.12864.12864.2 0.0156 16-Aug K.AFADPEVLR.R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1016.5291 2.6 19899 12864 2 1016.532642 509.2718 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2899.1 - 335525 - - - 3.4893 - 1.379 0.251 - 227.8 1 2 0 0.0035 9 0 0 0 7.32E+07 2.81E+07 - - - 1.8235 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.12868.12868.2 1.26 12-Jun R.TILMMGR.Y sp|P13639|EF2_HUMAN 1 820.4299 1.51 19901 12868 2 820.431875 411.2222 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 9.41 2899.6 - 4.29E+06 - - - 2.389 - 1.232 0.259 - 148.4 1 2 0 0.002 7 0 0 0 1.28E+08 8.53E+07 - - - 1.6144 0.998 230117_WJC_METTL3_WT_vs_EV_F03.12870.12870.2 0.011 14-Jul K.FQNALLVR.Y "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 959.5553 999 19903 12870 2 959.558092 480.7849 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 9.75 2899.8 - 215486 - - - 2.9618 - 1.549 0.258 - 156.4 1 2 0 0.0028 8 0 0 0 1.05E+08 0.00E+00 - - - 2.2655 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.12874.12874.2 8.95E-05 26-Oct R.LVPGGGATEIELAK.Q sp|P50990|TCPQ_HUMAN 1 1353.7504 44.27 19905 12874 2 1353.752702 677.8825 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 2900.4 - 137229 - - - 1.7145 - 2.027 0.492 - 216.1 1 2 0 0.0023 14 0 0 0 3.32E+07 7.49E+05 - - - 4.4473 0.9946 230117_WJC_METTL3_WT_vs_EV_F03.12878.12878.2 3.42 16-Oct K.AIPLALEGK[136.11].D "sp|Q9NY93|DDX56_HUMAN,tr|F8WDT8|F8WDT8_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|F8WEI3|F8WEI3_HUMAN" 4 918.563 1.13 19908 12878 2 918.565058 460.2888 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 6.05 2900.8 - 515542 - - - 2.2753 - 1.3 0.172 - 204 1 2 0 0.0021 9 0 0 0 2.29E+07 2.02E+07 - - - 1.0698 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.12883.12883.2 1.73 16-Aug K.AIPLALEGK.D "sp|Q9NY93|DDX56_HUMAN,tr|F8WDT8|F8WDT8_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|F8WEI3|F8WEI3_HUMAN" 4 910.5488 1.08 19911 12883 2 910.550885 456.2817 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 6.05 2901.5 - 528945 - - - 2.325 - 1.563 0.17 - 163.6 1 2 0 0.0021 9 0 0 0 2.13E+07 1.98E+07 - - - 1.588 0.9669 230117_WJC_METTL3_WT_vs_EV_F03.12889.12889.2 0.115 18-Oct R.RVLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1125.687 1.07 19915 12889 2 1125.696059 563.8508 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2902.3 - 625303 - - - 8.0537 - 1.814 0.264 - 288.8 1 2 0 0.0091 10 0 0 0 1.75E+07 1.63E+07 - - - 2.6504 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.12891.12891.2 0.00631 16-Aug R.LVPLVNGVR.E "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 965.6022 3.11 19916 12891 2 965.605373 483.8084 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 9.75 2902.5 - 1.60E+06 - - - 3.285 - 1.604 0.345 - 236.6 1 2 0 0.0032 9 0 0 0 1.35E+08 4.35E+07 - - - 2.9551 0.9845 230117_WJC_METTL3_WT_vs_EV_F03.12892.12892.2 0.189 14-Jul K.LISGWVSR.S "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 916.5131 1.43 19917 12892 2 916.516536 459.2638 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 9.75 2902.5 - 1.09E+06 - - - 3.8025 - 1.253 0.168 - 110.8 1 2 0 0.0035 8 0 0 0 4.64E+07 3.25E+07 - - - 0.961 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.12893.12893.2 0.000286 16-Aug K.AFADPEVLR[166.11].R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1026.5374 2.56 19918 12893 2 1026.540248 514.276 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2902.7 - 497084 - - - 2.8085 - 1.431 0.454 - 233.7 1 2 0 0.0029 9 0 0 0 7.21E+07 2.81E+07 - - - 3.4301 0.946 230117_WJC_METTL3_WT_vs_EV_F03.12894.12894.2 1.94 12-Jun R.LLEIVER.Q sp|Q12792|TWF1_HUMAN 1 870.5175 1.16 19919 12894 2 870.522732 436.266 Twinfilin-1 OS=Homo sapiens OX=9606 GN=TWF1 PE=1 SV=3 4.53 2902.8 - 364486 - - - 6.047 - 1.451 0.126 - 106.4 1 2 0 0.0053 7 0 0 0 4.72E+07 4.05E+07 - - - 1.1495 0.9919 230117_WJC_METTL3_WT_vs_EV_F03.12896.12896.2 0.996 14-Jul R.ILLVGEPR.V "sp|Q8IXI2|MIRO1_HUMAN,tr|J3KSR5|J3KSR5_HUMAN" 2 895.5491 1.33 19921 12896 2 895.551713 448.7818 Mitochondrial Rho GTPase 1 OS=Homo sapiens OX=9606 GN=RHOT1 PE=1 SV=2 6 2903.1 - 293956 - - - 2.9155 - 1.483 0.108 - 147.3 1 2 0 0.0026 8 0 0 0 1.78E+07 1.34E+07 - - - 1.0264 0.8745 230117_WJC_METTL3_WT_vs_EV_F03.12906.12906.2 0.000699 16-Oct L.VNHFVEEFK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1147.5662 999 19927 12906 2 1147.56479 574.7904 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2904.3 - 640149 - - - -1.2365 - 1.498 0.383 - 142.4 1 1 0 -0.0014 9 0 0 0 4.78E+06 0.00E+00 - - - 3.0386 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.12907.12907.2 0.014 16-Sep R.LVPLVNGVR[166.11].E "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 975.6105 3.11 19928 12907 2 975.612465 488.8125 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 9.75 2904.3 - 1.04E+06 - - - 2.0438 - 1.553 0.312 - 252.7 1 2 0 0.002 9 0 0 0 1.35E+08 4.35E+07 - - - 2.6183 0.9609 230117_WJC_METTL3_WT_vs_EV_F03.12930.12930.2 0.831 14-May K.GYGFGMVK.L "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RFL1|E5RFL1_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 6 857.4106 1.16 19938 12930 2 857.413082 429.7126 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 8.59 2907.6 - 385124 - - - 2.9414 - 0.855 0.202 - 41 2 2 0 0.0025 8 0 0 0 2.56E+07 2.20E+07 - - - -0.0748 0.9946 230117_WJC_METTL3_WT_vs_EV_F03.12933.12933.2 2.47 12-Jul R.VAIFIEK.T sp|Q9P258|RCC2_HUMAN 1 818.4902 1.73 19939 12933 2 818.490814 410.2524 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2908 - 1.05E+06 - - - 0.7612 - 1.243 0.168 - 157.7 1 2 0 0.0006 7 0 0 0 8.96E+07 5.17E+07 - - - 0.9709 0.8554 230117_WJC_METTL3_WT_vs_EV_F03.12937.12937.2 0.43 12-Aug A.LLLIESR.C "sp|Q15386|UBE3C_HUMAN,sp|P62277|RS13_HUMAN,sp|Q14406|CSHL_HUMAN,tr|J3QT06|J3QT06_HUMAN,tr|H0YKQ4|H0YKQ4_HUMAN,tr|A0A0B4J1R0|A0A0B4J1R0_HUMAN,tr|H7C3R7|H7C3R7_HUMAN" 7 842.5226 0.75 19941 12937 2 842.523534 422.2686 Ubiquitin-protein ligase E3C OS=Homo sapiens OX=9606 GN=UBE3C PE=1 SV=3 6 2908.4 - 7.31E+06 - - - 1.1644 - 1.694 0.13 - 240.4 1 1 0 0.001 7 0 0 0 6.13E+09 8.17E+09 - - - 1.671 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.12944.12944.2 0.232 12-Aug R.VAIFIEK[136.11].T sp|Q9P258|RCC2_HUMAN 1 826.5044 1.74 19943 12944 2 826.503903 414.2595 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2909.4 - 1.07E+06 - - - -0.5904 - 1.929 0.129 - 236.1 1 2 0 -0.0005 7 0 0 0 8.96E+07 5.16E+07 - - - 2.0754 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.12948.12948.2 0.0106 18-Jul R.LGLMPPPEPK.V sp|O43395|PRPF3_HUMAN 1 1077.5893 4.32 19945 12948 2 1077.59006 539.8019 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6 2909.8 - 153794 - - - 0.7489 - 1.611 0.307 - 124.7 1 2 0 0.0008 10 0 0 0 1.21E+07 2.80E+06 - - - 2.6393 0.9916 230117_WJC_METTL3_WT_vs_EV_F03.12951.12951.2 1.66 14-Oct K.LALLEEAR[166.11].T "sp|Q5TZA2|CROCC_HUMAN,sp|P15311|EZRI_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|B1AKD8|B1AKD8_HUMAN" 4 923.5316 1.52 19947 12951 2 923.531306 462.7731 Rootletin OS=Homo sapiens OX=9606 GN=CROCC PE=1 SV=1 4.53 2910.1 - 580819 - - - -0.2664 - 1.501 0.098 - 306.1 1 2 0 -0.0002 8 0 0 0 3.26E+07 2.15E+07 - - - 0.9896 0.999 230117_WJC_METTL3_WT_vs_EV_F03.12952.12952.2 0.0282 16-Jun K.MLVVGGIDR[166.11].V sp|Q15046|SYK_HUMAN 1 968.5353 1.13 19948 12952 2 968.535285 485.2749 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2910.2 - 2.65E+06 - - - 0.0289 - 1.505 0.353 - 139.2 1 2 0 0 9 0 0 0 1.59E+08 1.41E+08 - - - 2.8309 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.12956.12956.2 0.00984 16-Jul K.MLVVGGIDR.V sp|Q15046|SYK_HUMAN 1 958.527 1.13 19950 12956 2 958.527223 480.2708 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2910.8 - 2.94E+06 - - - 0.2462 - 1.54 0.343 - 247.9 1 2 0 0.0002 9 0 0 0 1.60E+08 1.41E+08 - - - 2.8235 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.12960.12960.2 0.305 12-Aug K.ILEVDLK[136.11].N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 836.5099 0.92 19953 12960 2 836.510385 419.2622 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2911.2 - 955678 - - - 0.6157 - 1.571 0.146 - 158.7 1 2 0 0.0005 7 0 0 0 1.54E+08 1.68E+08 - - - 1.5505 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.13003.13003.3 7.14E-05 14/44 R.LIDLHSPSEIVK.Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1349.7555 1.99 19964 13003 3 1349.754607 450.9258 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2917.6 - 1.07E+06 - - - -0.6372 - 2.354 0.437 - 232.4 1 2 0 -0.0009 12 0 0 0 3.50E+07 1.76E+07 - - - 5.7849 0.9721 230117_WJC_METTL3_WT_vs_EV_F03.13009.13009.2 1.52 14-Jul K.LEPVVFEK[136.11].V "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 967.547 3.99 19968 13009 2 967.546228 484.7808 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 2918.3 - 454424 - - - -0.7814 - 1.236 0.09 - 146.6 1 2 0 -0.0008 8 0 0 0 1.11E+08 2.78E+07 - - - 0.3445 0.9934 230117_WJC_METTL3_WT_vs_EV_F03.13010.13010.2 0.235 14-Jul K.FIINSYPK[136.11].Y "sp|Q96EY7|PTCD3_HUMAN,tr|B8ZZQ4|B8ZZQ4_HUMAN" 2 988.5473 1.01 19969 13010 2 988.547395 495.2809 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 8.59 2918.4 - 396993 - - - 0.0779 - 1.209 0.191 - 112.3 1 2 0 0.0001 8 0 0 0 1.19E+07 1.17E+07 - - - 1.0241 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.13026.13026.2 0.0043 14-Sep K.VVLVLAGR[166.11].Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 835.5519 0.78 19978 13026 2 835.553897 418.7832 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2920.5 - 5.41E+06 - - - 2.3984 - 1.898 0.338 - 309.9 1 2 0 0.002 8 0 0 0 1.95E+09 2.49E+09 - - - 3.4695 0.9795 230117_WJC_METTL3_WT_vs_EV_F03.13027.13027.2 4.24 12-Jul R.AFGIPVR[166.11].C sp|Q00535|CDK5_HUMAN 1 768.4522 1.38 19979 13027 2 768.452851 385.2334 Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3 9.79 2920.6 - 726096 - - - 0.8745 - 1.127 0.081 - 149.4 1 2 0 0.0007 7 0 0 0 8.12E+07 5.90E+07 - - - 0.0179 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.13028.13028.2 0.00437 14-Sep K.VVLVLAGR.Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 825.5436 0.78 19980 13028 2 825.544734 413.7791 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2920.7 - 2.66E+06 - - - 1.3458 - 1.702 0.433 - 394.9 1 2 0 0.0011 8 0 0 0 1.95E+09 2.49E+09 - - - 3.8427 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.13029.13029.2 0.173 14-Aug R.QMAAVLLR[166.11].R "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 11 910.5298 1.31 19981 13029 2 910.53029 456.2722 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 2920.7 - 701376 - - - 0.5623 - 1.604 0.159 - 236.4 1 2 0 0.0005 8 0 0 0 5.84E+07 4.46E+07 - - - 1.6403 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.13031.13031.2 0.00731 18-Jul R.VNC[160.03]LAPGLIK[136.11].T "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN" 3 1091.6253 0.88 19983 13031 2 1091.626045 546.8199 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 8.19 2921 - 280343 - - - 0.7274 - 1.368 0.332 - 123.8 1 2 0 0.0008 10 0 0 0 7.61E+06 8.61E+06 - - - 2.3676 0.9962 230117_WJC_METTL3_WT_vs_EV_F03.13036.13036.2 0.018 14-Jul K.LTPVLLAK[136.11].Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 861.5779 1.65 19986 13036 2 861.578148 431.7962 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2921.7 - 4.76E+06 - - - 0.2995 - 1.225 0.234 - 153.9 1 2 0 0.0003 8 0 0 0 2.59E+08 1.57E+08 - - - 1.3813 0.9456 230117_WJC_METTL3_WT_vs_EV_F03.13037.13037.2 0.222 12-Jul R.LSSFIVK.E sp|P24278|ZBT25_HUMAN 1 792.4745 0.78 19987 13037 2 792.472437 397.2445 Zinc finger and BTB domain-containing protein 25 OS=Homo sapiens OX=9606 GN=ZBTB25 PE=1 SV=2 8.75 2921.7 - 1.52E+06 - - - -2.655 - 1.564 0.05 - 121.2 2 2 0 -0.0021 7 0 0 0 4.46E+07 5.69E+07 - - - 0.6923 0.9415 230117_WJC_METTL3_WT_vs_EV_F03.13039.13039.2 0.00313 12-Jul K.PIIFDC[160.03]R[166.11].S "sp|P35232|PHB_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 4 929.4668 2.41 19989 13039 2 929.468446 465.7407 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 6.22 2922 - 145613 - - - 1.7246 - 1.362 0.362 - 157.8 1 1 0 0.0016 7 0 0 0 6.84E+06 2.84E+06 - - - 2.6932 0.9673 230117_WJC_METTL3_WT_vs_EV_F03.13054.13054.2 1.96 12-Jun K.LSSLFVK[136.11].C sp|Q92616|GCN1_HUMAN 1 800.4887 0.79 19998 13054 2 800.489984 401.2516 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.75 2923.8 - 1.76E+06 - - - 1.5528 - 1.395 0.019 - 63.1 17 2 0 0.0012 7 0 0 0 4.68E+07 5.91E+07 - - - -0.3139 0.9898 230117_WJC_METTL3_WT_vs_EV_F03.13061.13061.2 0.905 14-Jun K.LTPVLLAK.Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 853.5637 1.65 20003 13061 2 853.564917 427.7891 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2924.7 - 9.77E+06 - - - 1.4375 - 1.004 0.19 - 99.6 1 2 0 0.0012 8 0 0 0 2.59E+08 1.57E+08 - - - 0.456 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.13062.13062.2 0.0606 12-Aug R.FASFIER[166.11].V sp|P07196|NFL_HUMAN 1 878.4526 1.51 20004 13062 2 878.453741 440.2336 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2924.7 - 1.48E+06 - - - 1.3296 - 1.606 0.237 - 200.8 1 2 0 0.0012 7 0 0 0 1.03E+08 6.81E+07 - - - 2.2922 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.13065.13065.2 0.00203 18-Oct R.VNC[160.03]LAPGLIK.T "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN" 3 1083.6111 0.88 20005 13065 2 1083.613489 542.8128 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 8.19 2925.1 - 398888 - - - 2.2499 - 1.917 0.379 - 346.3 1 2 0 0.0024 10 0 0 0 7.61E+06 8.61E+06 - - - 3.656 0.9359 230117_WJC_METTL3_WT_vs_EV_F03.13072.13072.2 6.08 14-Jun K.LLAEVTLK[136.11].T "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 4 893.5677 2.59 20010 13072 2 893.567971 447.7911 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 6 2926 - 401340 - - - 0.282 - 0.952 0.068 - 70.1 1 2 0 0.0003 8 0 0 0 1.58E+08 6.10E+07 - - - -0.6052 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.13082.13082.2 0.279 14-Aug K.LLAEVTLK.T "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 4 885.5535 2.59 20015 13082 2 885.554755 443.784 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 6 2927.1 - 2.40E+06 - - - 1.3957 - 1.374 0.228 - 140.3 1 2 0 0.0012 8 0 0 0 1.58E+08 6.08E+07 - - - 1.6829 0.9932 230117_WJC_METTL3_WT_vs_EV_F03.13083.13083.2 4.93 12-Jun R.LISSLLR.T "sp|Q9BQ52|RNZ2_HUMAN,sp|Q8NCN5|PDPR_HUMAN,sp|Q96P20|NLRP3_HUMAN,sp|Q96MN2|NALP4_HUMAN,sp|Q8NGV5|O13D1_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|A0A7I2PMC6|A0A7I2PMC6_HUMAN,tr|E7ES68|E7ES68_HUMAN,tr|A0A2R8YEG7|A0A2R8YEG7_HUMAN,tr|A8MT40|A8MT40_HUMAN,tr|A0A7I2PJH0|A0A7I2PJH0_HUMAN,tr|H3BQG3|H3BQG3_HUMAN,tr|A0A7I2PRX0|A0A7I2PRX0_HUMAN,tr|A0A7I2YME5|A0A7I2YME5_HUMAN,tr|A0A286YF94|A0A286YF94_HUMAN,tr|A0A7I2UNQ2|A0A7I2UNQ2_HUMAN,tr|A0A7I2R3P8|A0A7I2R3P8_HUMAN" 17 800.512 1.48 20016 13083 2 800.513406 401.2633 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 9.75 2927.2 - 1.86E+06 - - - 1.7701 - 1.444 0.077 - 105.5 1 2 0 0.0014 7 0 0 0 3.17E+07 2.14E+07 - - - 0.7735 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.13088.13088.2 0.08 12-Aug K.VVIDAFR.L sp|O00487|PSDE_HUMAN 1 818.465 1.76 20018 13088 2 818.466478 410.2398 26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1 5.81 2927.8 - 9.91E+06 - - - 1.7594 - 1.465 0.258 - 313.5 1 2 0 0.0014 7 0 0 0 3.75E+08 2.12E+08 - - - 2.1561 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.13096.13096.2 0.0631 12-Aug R.FASFIER.V sp|P07196|NFL_HUMAN 1 868.4443 1.51 20022 13096 2 868.44553 435.2294 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2928.8 - 3.13E+06 - - - 1.4129 - 1.616 0.239 - 196.2 1 2 0 0.0012 7 0 0 0 1.03E+08 6.81E+07 - - - 2.3266 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.13103.13103.2 0.00105 20-Aug K.YGQISEVVVVK[136.11].D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1227.6954 0.9 20025 13103 2 1227.695487 614.855 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2929.8 - 91236.8 - - - 0.0391 - 1.598 0.404 - 174.1 1 2 0 0 11 0 0 0 4.78E+06 5.29E+06 - - - 3.293 0.99 230117_WJC_METTL3_WT_vs_EV_F03.13108.13108.2 1.18 12-Jul R.VNLLAVR.D "sp|Q9H4H8|FA83D_HUMAN,tr|A0A087WXK8|A0A087WXK8_HUMAN" 2 783.4967 1.98 20027 13108 2 783.496822 392.7556 Protein FAM83D OS=Homo sapiens OX=9606 GN=FAM83D PE=1 SV=3 9.72 2930.6 - 713529 - - - 0.1902 - 1.477 0.054 - 111 1 2 0 0.0001 7 0 0 0 1.88E+07 9.50E+06 - - - 0.6756 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.13114.13114.2 1.02 12-Jul K.ILMEFNK[136.11].M sp|Q9UQE7|SMC3_HUMAN 1 901.4823 1.58 20029 13114 2 901.483449 451.7484 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2931.4 - 871728 - - - 1.3023 - 1.219 0.182 - 104.3 1 2 0 0.0012 7 0 0 0 7.56E+07 4.77E+07 - - - 1.0124 0.9667 230117_WJC_METTL3_WT_vs_EV_F03.13117.13117.2 2.71 12-Jun K.ILMEFNK.M sp|Q9UQE7|SMC3_HUMAN 1 893.4681 1.54 20030 13117 2 893.469511 447.7413 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2931.8 - 2.52E+06 - - - 1.6072 - 0.987 0.092 - 75.4 1 2 0 0.0014 7 0 0 0 5.84E+07 3.79E+07 - - - -0.3214 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.13120.13120.2 0.000791 20-Aug K.YGQISEVVVVK.D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1219.6812 0.9 20033 13120 2 1219.684725 610.8479 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2932.2 - 229179 - - - 2.8581 - 1.403 0.463 - 150.4 1 2 0 0.0035 11 0 0 0 4.78E+06 5.29E+06 - - - 3.3757 0.9965 230117_WJC_METTL3_WT_vs_EV_F03.13123.13123.2 0.0885 14-Aug K.IGDFGLAR.D "sp|P08922|ROS1_HUMAN,sp|P07333|CSF1R_HUMAN,sp|P51617|IRAK1_HUMAN,sp|Q96PY6|NEK1_HUMAN,sp|P51955|NEK2_HUMAN,sp|Q6P3R8|NEK5_HUMAN,sp|Q16659|MK06_HUMAN,sp|P31152|MK04_HUMAN,tr|E9PIX7|E9PIX7_HUMAN,tr|H7C2I6|H7C2I6_HUMAN,tr|K7EN18|K7EN18_HUMAN,tr|A0A494C168|A0A494C168_HUMAN,tr|F6U4U2|F6U4U2_HUMAN,tr|H7C224|H7C224_HUMAN,tr|K7ELV1|K7ELV1_HUMAN,tr|Q5H8Y1|Q5H8Y1_HUMAN,tr|A0A3B3ITQ6|A0A3B3ITQ6_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 18 847.4552 2.28 20034 13123 2 847.455531 424.7349 Proto-oncogene tyrosine-protein kinase ROS OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3 5.84 2932.6 - 1.17E+06 - - - 0.3882 - 1.885 0.064 - 167.8 1 2 0 0.0003 8 0 0 0 6.73E+07 2.95E+07 - - - 1.4255 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.13125.13125.2 1.13 14-Aug K.LALDYGIK[136.11].F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 899.5208 0.72 20036 13125 2 899.523388 450.7677 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 2932.8 - 741237 - - - 2.9116 - 1.678 0.191 - 143.6 1 2 0 0.0026 8 0 0 0 2.94E+07 4.07E+07 - - - 2.012 0.9955 230117_WJC_METTL3_WT_vs_EV_F03.13130.13130.2 2.44 12-Jul R.LALEELR.S sp|Q99496|RING2_HUMAN 1 842.4862 1.11 20039 13130 2 842.486566 422.2504 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.53 2933.4 - 516255 - - - 0.4724 - 1.504 0.115 - 150.7 1 2 0 0.0004 7 0 0 0 2.49E+08 2.25E+08 - - - 1.1834 0.9848 230117_WJC_METTL3_WT_vs_EV_F03.13135.13135.2 3.13 14-Jul R.NVVYPLYR.L "sp|Q16540|RM23_HUMAN,tr|A8MYK1|A8MYK1_HUMAN,tr|A8MVT4|A8MVT4_HUMAN,tr|A6NJD9|A6NJD9_HUMAN" 4 1022.5549 999 20042 13135 2 1022.556209 512.2847 "39S ribosomal protein L23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL23 PE=1 SV=1" 8.59 2934 - 1.13E+06 - - - 1.2645 - 1.217 0.075 - 175.7 1 2 0 0.0013 8 0 0 0 2.87E+07 0.00E+00 - - - 0.1868 0.8772 230117_WJC_METTL3_WT_vs_EV_F03.13136.13136.2 0.559 14-May R.LFAAELGR.E "sp|O00255|MEN1_HUMAN,tr|A0A5F9ZHS3|A0A5F9ZHS3_HUMAN,tr|E7EN32|E7EN32_HUMAN,tr|Q9GZQ5|Q9GZQ5_HUMAN,tr|E7ENS2|E7ENS2_HUMAN" 5 875.4865 1.53 20043 13136 2 875.491896 438.7505 Menin OS=Homo sapiens OX=9606 GN=MEN1 PE=1 SV=4 6 2934.1 - 573679 - - - 6.1611 - 1.144 0.178 - 43.2 3 2 0 0.0054 8 0 0 0 3.72E+07 2.43E+07 - - - 0.5466 0.9783 230117_WJC_METTL3_WT_vs_EV_F03.13141.13141.2 7.95 14-Apr K.VLPITVPK[136.11].S sp|Q9ULW0|TPX2_HUMAN 1 873.5779 2.08 20046 13141 2 873.578775 437.7962 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.72 2934.8 - 457755 - - - 1.0131 - 0.751 0.293 - 22 7 2 0 0.0009 8 0 0 0 5.40E+07 2.59E+07 - - - -0.0363 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.13143.13143.2 0.457 14-May K.VLPITVPK.S sp|Q9ULW0|TPX2_HUMAN 1 865.5637 2.07 20048 13143 2 865.564395 433.7891 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.72 2935 - 908605 - - - 0.8145 - 1.072 0.308 - 60.8 1 2 0 0.0007 8 0 0 0 5.40E+07 2.60E+07 - - - 1.5254 0.9957 230117_WJC_METTL3_WT_vs_EV_F03.13148.13148.2 0.0363 14-Jul R.IFNTFGPR[166.11].M "sp|Q8NBZ7|UXS1_HUMAN,tr|C9JCB7|C9JCB7_HUMAN,tr|C9JFU6|C9JFU6_HUMAN,tr|C9JE50|C9JE50_HUMAN" 4 960.5057 0.77 20051 13148 2 960.50403 481.2601 UDP-glucuronic acid decarboxylase 1 OS=Homo sapiens OX=9606 GN=UXS1 PE=1 SV=1 9.75 2935.6 - 783952 - - - -1.7085 - 1.526 0.278 - 104.8 1 2 0 -0.0016 8 0 0 0 3.26E+07 4.23E+07 - - - 2.3685 0.8987 230117_WJC_METTL3_WT_vs_EV_F03.13156.13156.2 0.0111 16-Jul Y.GYIVAAVVK.L sp|Q8NGI9|OR5A2_HUMAN 1 918.5539 42.54 20056 13156 2 918.554344 460.2842 Olfactory receptor 5A2 OS=Homo sapiens OX=9606 GN=OR5A2 PE=2 SV=1 8.59 2936.6 - 596590 - - - 0.5334 - 1.33 0.313 - 131.2 1 1 0 0.0005 9 0 0 0 1.48E+07 3.48E+05 - - - 2.1777 0.9194 230117_WJC_METTL3_WT_vs_EV_F03.13161.13161.2 0.0037 14-Aug E.ILNPLVSK.A "sp|Q6NUP7|PP4R4_HUMAN,sp|Q9BSC4|NOL10_HUMAN,tr|G3V431|G3V431_HUMAN" 3 882.5539 1.07 20059 13161 2 882.553669 442.2842 Serine\threonine-protein phosphatase 4 regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PPP4R4 PE=1 SV=1 8.75 2937.2 - 2.39E+06 - - - -0.2096 - 1.431 0.369 - 141.5 1 1 0 -0.0002 8 0 0 0 8.45E+07 7.92E+07 - - - 2.8472 0.9524 230117_WJC_METTL3_WT_vs_EV_F03.13162.13162.2 1.52 16-Jun K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 9.71 20060 13162 2 1014.538171 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 2937.3 - 693616 - - - 3.5445 - 1.197 0.083 - 56.9 2 2 0 0.0036 9 0 0 0 2.53E+07 2.60E+06 - - - 0.0387 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.13164.13164.2 0.0815 16-Sep R.ILVLNGGYR.G "sp|O60870|KIN17_HUMAN,tr|S4R357|S4R357_HUMAN" 2 1003.5815 1.92 20062 13164 2 1003.581991 502.798 DNA\RNA-binding protein KIN17 OS=Homo sapiens OX=9606 GN=KIN PE=1 SV=2 8.75 2937.4 - 852871 - - - 0.5241 - 1.779 0.34 - 239.5 1 2 0 0.0005 9 0 0 0 1.74E+07 9.07E+06 - - - 3.2186 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.13179.13179.2 0.137 14-Oct K.INELLLAK.E "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 912.5644 3.03 20073 13179 2 912.565629 457.2895 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 6 2939.2 - 1.50E+06 - - - 1.327 - 1.923 0.279 - 241.9 1 2 0 0.0012 8 0 0 0 6.22E+07 2.05E+07 - - - 3.0734 0.9921 230117_WJC_METTL3_WT_vs_EV_F03.13190.13190.2 0.0285 16-Jul R.EQVNDLFSR.K "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1106.5356 0.35 20080 13190 2 1106.540324 554.2751 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 2940.6 - 268495 - - - 4.2357 - 1.288 0.269 - 119.7 1 2 0 0.0047 9 0 0 0 3.44E+06 9.74E+06 - - - 1.7586 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.13193.13193.2 0.609 16-Aug K.LLSGNLALR[166.11].S sp|Q53S58|TM177_HUMAN 1 965.5897 1.01 20083 13193 2 965.590161 483.8021 Transmembrane protein 177 OS=Homo sapiens OX=9606 GN=TMEM177 PE=1 SV=1 9.75 2940.9 - 254678 - - - 0.4412 - 1.716 0.248 - 134.5 1 2 0 0.0004 9 0 0 0 7.53E+06 7.47E+06 - - - 2.4348 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.13197.13197.2 0.109 14-Sep K.VVNPLFEK[136.11].R "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 952.5473 0.85 20085 13197 2 952.548606 477.2809 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.97 2941.4 - 2.06E+06 - - - 1.3522 - 1.784 0.368 - 238.5 1 2 0 0.0013 8 0 0 0 1.02E+08 1.21E+08 - - - 3.5045 0.8818 230117_WJC_METTL3_WT_vs_EV_F03.13206.13206.2 6.1 16-May K.KLPVTFEDK.K "sp|Q15811|ITSN1_HUMAN,sp|Q9NZM3|ITSN2_HUMAN,tr|C9JQZ7|C9JQZ7_HUMAN,tr|F8W7U0|F8W7U0_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN,tr|A8CTZ0|A8CTZ0_HUMAN,tr|E7EPJ2|E7EPJ2_HUMAN" 7 1075.5914 999 20091 13206 2 1075.590807 538.803 Intersectin-1 OS=Homo sapiens OX=9606 GN=ITSN1 PE=1 SV=3 6.07 2942.5 - 494023 - - - -0.5151 - 1.308 0.005 - 57.9 22 2 0 -0.0006 9 0 0 0 1.55E+07 0.00E+00 - - - -0.7451 0.9941 230117_WJC_METTL3_WT_vs_EV_F03.13212.13212.2 0.18 14-Jun R.LFVGSIPK.S "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 859.5167 0.9 20095 13212 2 859.516994 430.7656 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.75 2943.1 - 2.48E+06 - - - 0.2955 - 1.17 0.206 - 118.8 1 2 0 0.0003 8 0 0 0 1.33E+09 1.49E+09 - - - 1.036 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.13216.13216.2 0.329 12-Aug R.NLPMHLR.R "sp|Q9P2E3|ZNFX1_HUMAN,tr|Q5JXR6|Q5JXR6_HUMAN,tr|Q5JXR7|Q5JXR7_HUMAN,tr|Q5JXR5|Q5JXR5_HUMAN" 4 879.4749 391.41 20097 13216 2 879.475238 440.7447 NFX1-type zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=ZNFX1 PE=2 SV=2 9.76 2943.7 - 4.65E+06 - - - 0.3934 - 1.457 0.237 - 254.5 1 2 0 0.0003 7 0 0 0 1.75E+08 4.46E+05 - - - 1.984 0.988 230117_WJC_METTL3_WT_vs_EV_F03.13218.13218.2 2.02 12-Jun K.FIPLYSK[136.11].V "sp|Q14694|UBP10_HUMAN,tr|J3KT19|J3KT19_HUMAN,tr|H3BVF1|H3BVF1_HUMAN" 3 874.5044 1.19 20099 13218 2 874.505176 438.2595 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.59 2943.9 - 333642 - - - 0.8977 - 1.073 0.15 - 87.9 1 2 0 0.0008 7 0 0 0 1.01E+08 8.52E+07 - - - 0.3719 0.9283 230117_WJC_METTL3_WT_vs_EV_F03.13228.13228.2 0.0943 16-Aug H.VVVLVATVR[166.11].A "sp|P11586|C1TC_HUMAN,sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 8 964.6309 2.58 20105 13228 2 964.631682 483.3227 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.72 2945.1 - 275786 - - - 0.8397 - 1.732 0.25 - 199.4 1 1 0 0.0008 9 0 0 0 2.36E+07 9.14E+06 - - - 2.4763 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.13230.13230.2 0.242 14-Aug R.IFTNLYGR.H "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 4 982.5236 1.14 20107 13230 2 982.52605 492.2691 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.75 2945.4 - 211205 - - - 2.4773 - 1.544 0.205 - 170.5 1 2 0 0.0024 8 0 0 0 5.69E+07 4.99E+07 - - - 1.8644 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.13234.13234.2 3.44E-05 14-Sep -.MFAPAVMR[166.11].A sp|Q9P0S2|COX16_HUMAN 1 931.4647 1.6 20109 13234 2 931.463916 466.7396 "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COX16 PE=1 SV=1" 9.5 2945.9 - 412993 - - - -0.8782 - 1.793 0.194 - 316.1 1 2 0 -0.0008 8 0 0 0 3.82E+07 2.39E+07 - - - 2.2346 0.9752 230117_WJC_METTL3_WT_vs_EV_F03.13248.13248.2 0.358 12-Jul R.SVTLLIK.G sp|P40227|TCPZ_HUMAN 1 772.5058 8.24 20118 13248 2 772.506514 387.2602 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 8.47 2947.6 - 2.65E+06 - - - 0.8712 - 1.263 0.015 - 157 1 2 0 0.0007 7 0 0 0 3.31E+09 4.02E+08 - - - -0.1086 0.9826 230117_WJC_METTL3_WT_vs_EV_F03.13260.13260.2 0.626 22-Jul R.LLLGPAGGGVPK.L sp|Q96SL8|FIZ1_HUMAN 1 1077.6546 1.33 20124 13260 2 1077.658089 539.8346 Flt3-interacting zinc finger protein 1 OS=Homo sapiens OX=9606 GN=FIZ1 PE=1 SV=2 8.75 2949.3 - 256478 - - - 3.2097 - 1.362 0.1 - 80.8 1 2 0 0.0035 12 0 0 0 1.02E+07 7.66E+06 - - - 0.5914 0.987 230117_WJC_METTL3_WT_vs_EV_F03.13267.13267.2 3.46 12-Jul K.SVIISIK[136.11].G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 766.5044 1.15 20127 13267 2 766.505218 384.2595 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2950.2 - 1.56E+06 - - - 1.0789 - 1.147 0.112 - 190.6 1 2 0 0.0008 7 0 0 0 1.92E+08 1.67E+08 - - - 0.3025 0.9946 230117_WJC_METTL3_WT_vs_EV_F03.13269.13269.2 0.771 12-Jul K.SVIISIK.G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 758.4902 1.15 20129 13269 2 758.490603 380.2524 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2950.3 - 1.20E+06 - - - 0.5432 - 1.253 0.171 - 194.6 1 2 0 0.0004 7 0 0 0 1.92E+08 1.67E+08 - - - 1.0185 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.13276.13276.2 0.0111 14-Sep R.LLAAFEER.E "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 947.5076 1.29 20130 13276 2 947.508243 474.7611 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.53 2951.5 - 2.18E+06 - - - 0.6448 - 2.045 0.346 - 270.9 1 2 0 0.0006 8 0 0 0 1.46E+08 1.13E+08 - - - 3.754 0.9851 230117_WJC_METTL3_WT_vs_EV_F03.13279.13279.2 1.85 14-Jul K.NLILAGVK.G "sp|Q9UBE0|SAE1_HUMAN,tr|B3KNJ4|B3KNJ4_HUMAN,tr|M0QZS6|M0QZS6_HUMAN,tr|A0A590UKC5|A0A590UKC5_HUMAN,tr|M0QX65|M0QX65_HUMAN,tr|A0A590UKA0|A0A590UKA0_HUMAN,tr|A0A590UK93|A0A590UK93_HUMAN" 7 826.5276 3.54 20132 13279 2 826.527316 414.2711 SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1 PE=1 SV=1 8.75 2951.8 - 894882 - - - -0.3908 - 1.53 0.04 - 145.4 1 2 0 -0.0003 8 0 0 0 4.95E+07 1.40E+07 - - - 0.6189 0.9914 230117_WJC_METTL3_WT_vs_EV_F03.13282.13282.2 0.75 12-Jul R.IGLLDPR[166.11].W "sp|Q15459|SF3A1_HUMAN,tr|H7C1L2|H7C1L2_HUMAN" 2 792.4733 1.33 20134 13282 2 792.473279 397.2439 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 5.84 2952.1 - 1.64E+06 - - - -0.0366 - 1.315 0.159 - 96.3 3 2 0 0 7 0 0 0 3.21E+08 2.42E+08 - - - 0.8699 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.13284.13284.2 0.00671 14-May K.LVVWAADR.Q "sp|Q96RQ3|MCCA_HUMAN,tr|G5E9X5|G5E9X5_HUMAN,tr|E9PG35|E9PG35_HUMAN,tr|E9PHF7|E9PHF7_HUMAN,tr|F5GYT8|F5GYT8_HUMAN" 5 928.5131 2.21 20135 13284 2 928.51448 465.2638 "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC1 PE=1 SV=3" 5.84 2952.4 - 470527 - - - 1.539 - 1.305 0.304 - 56.8 1 2 0 0.0014 8 0 0 0 2.85E+07 1.29E+07 - - - 2.0888 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.13285.13285.2 0.000218 16-Aug R.EMGVIAAMR.D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 976.4834 2.98 20136 13285 2 976.484052 489.249 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 6.1 2952.5 - 327699 - - - 0.6605 - 1.632 0.428 - 169.8 1 2 0 0.0006 9 0 0 0 1.53E+07 5.11E+06 - - - 3.619 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.13290.13290.2 2.15 18-Nov R.LLAEPVPGIK[136.11].A "sp|P61088|UBE2N_HUMAN,sp|Q5JXB2|UE2NL_HUMAN,tr|F8VZ29|F8VZ29_HUMAN,tr|F8VSD4|F8VSD4_HUMAN,tr|F8VV71|F8VV71_HUMAN" 5 1043.647 1.66 20138 13290 2 1043.64865 522.8308 Ubiquitin-conjugating enzyme E2 N OS=Homo sapiens OX=9606 GN=UBE2N PE=1 SV=1 6 2953.1 - 742856 - - - 1.5503 - 1.736 0.182 - 285.8 1 2 0 0.0016 10 0 0 0 1.24E+08 7.48E+07 - - - 1.9244 0.997 230117_WJC_METTL3_WT_vs_EV_F03.13292.13292.2 1.86 12-Jul K.IVVLLQR.L "sp|Q06323|PSME1_HUMAN,tr|H0YLU2|H0YLU2_HUMAN" 2 839.5593 1.4 20140 13292 2 839.560275 420.7869 Proteasome activator complex subunit 1 OS=Homo sapiens OX=9606 GN=PSME1 PE=1 SV=1 9.75 2953.4 - 288759 - - - 1.1935 - 1.249 0.222 - 104.8 1 2 0 0.001 7 0 0 0 3.38E+07 2.41E+07 - - - 1.3849 1 230117_WJC_METTL3_WT_vs_EV_F03.13295.13295.2 3.00E-07 24-Nov R.TTPSYVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1486.694 14.15 20141 13295 2 1486.699827 744.3543 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2953.8 - 401759 - - - 3.9268 - 2.529 0.595 - 379.2 1 2 0 0.0058 13 0 0 0 6.94E+07 4.90E+06 - - - 5.8151 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.13299.13299.2 0.00887 14-Aug R.LLAAFEER[166.11].E "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 957.5159 1.31 20143 13299 2 957.516647 479.7652 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.53 2954.2 - 2.19E+06 - - - 0.7781 - 1.695 0.386 - 233.8 1 2 0 0.0007 8 0 0 0 1.51E+08 1.15E+08 - - - 3.4832 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.13306.13306.2 0.0517 16-Sep K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 488.3 20148 13306 2 1059.557436 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2955 - 610919 - - - 1.3194 - 1.508 0.317 - 239.6 1 2 0 0.0014 9 0 0 0 2.47E+07 5.07E+04 - - - 2.5703 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.13308.13308.2 0.368 14-Aug K.LVALNLDR.L "sp|Q9Y3D3|RT16_HUMAN,tr|A6ND22|A6ND22_HUMAN" 2 912.5393 1.19 20149 13308 2 912.539831 457.2769 "28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1" 5.84 2955.2 - 1.27E+06 - - - 0.6192 - 1.81 0.262 - 177.8 1 2 0 0.0006 8 0 0 0 8.32E+07 7.02E+07 - - - 2.7654 0.9775 230117_WJC_METTL3_WT_vs_EV_F03.13309.13309.2 4.95 12-Jun K.YVIYIER[166.11].V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 964.5257 0.83 20150 13309 2 964.525763 483.2701 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 6 2955.4 - 220860 - - - 0.0259 - 1.123 0.103 - 119.4 1 2 0 0 7 0 0 0 1.00E+09 1.21E+09 - - - 0.1693 0.9962 230117_WJC_METTL3_WT_vs_EV_F03.13313.13313.2 0.358 14-Jun R.ILEVLPGR.R sp|Q9UI43|MRM2_HUMAN 1 895.5491 2.59 20152 13313 2 895.552076 448.7818 "rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1" 6 2955.9 - 451855 - - - 3.3209 - 1.437 0.236 - 91.5 1 2 0 0.003 8 0 0 0 5.79E+07 2.24E+07 - - - 1.8766 0.9965 230117_WJC_METTL3_WT_vs_EV_F03.13319.13319.2 7.8 12-Aug K.LLDIVAR[166.11].S sp|Q12931|TRAP1_HUMAN 1 808.5046 2.81 20154 13319 2 808.504763 405.2596 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.84 2956.6 - 2.10E+06 - - - 0.1905 - 1.789 0.082 - 206.1 1 2 0 0.0002 7 0 0 0 2.92E+08 1.04E+08 - - - 1.4896 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.13327.13327.2 0.0626 14-Aug R.ILEVLPGR[166.11].R sp|Q9UI43|MRM2_HUMAN 1 905.5574 2.59 20158 13327 2 905.557273 453.786 "rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1" 6 2957.7 - 357309 - - - -0.1093 - 1.688 0.243 - 174.7 1 2 0 -0.0001 8 0 0 0 5.79E+07 2.24E+07 - - - 2.4148 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.13330.13330.2 0.867 12-Jun K.ELVVLPR.E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 824.512 0.51 20159 13330 2 824.513041 413.2633 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2958.1 - 722569 - - - 1.2759 - 1.406 0.162 - 174.9 1 2 0 0.0011 7 0 0 0 1.91E+08 3.78E+08 - - - 1.3169 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.13336.13336.2 0.327 12-Aug K.YVIYIER.V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 954.5175 0.83 20163 13336 2 954.518219 478.266 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 6 2958.9 - 1.64E+06 - - - 0.7868 - 1.647 0.272 - 274.8 1 2 0 0.0008 7 0 0 0 1.00E+09 1.21E+09 - - - 2.6307 0.9935 230117_WJC_METTL3_WT_vs_EV_F03.13342.13342.2 6.72 12-Jul K.LLDIVAR.S sp|Q12931|TRAP1_HUMAN 1 798.4963 2.2 20165 13342 2 798.496725 400.2554 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.84 2959.7 - 7.69E+06 - - - 0.4834 - 1.663 0.034 - 162 1 2 0 0.0004 7 0 0 0 2.97E+08 1.35E+08 - - - 0.9036 0.9933 230117_WJC_METTL3_WT_vs_EV_F03.13349.13349.2 0.357 14-Jul K.LVALNLDR[166.11].L "sp|Q9Y3D3|RT16_HUMAN,tr|A6ND22|A6ND22_HUMAN" 2 922.5475 1.22 20168 13349 2 922.5488 462.281 "28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1" 5.84 2960.6 - 1.66E+06 - - - 1.3701 - 1.282 0.131 - 162.5 1 2 0 0.0013 8 0 0 0 8.55E+07 7.03E+07 - - - 0.7574 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.13350.13350.2 0.000116 24-Aug R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 14.14 20169 13350 2 1496.704072 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2960.7 - 117454 - - - 1.2113 - 1.827 0.19 - 141.2 1 2 0 0.0018 13 0 0 0 6.94E+07 4.90E+06 - - - 1.9906 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.13356.13356.2 0.00817 12-Jul R.VVFQEFR[166.11].Q sp|P35579|MYH9_HUMAN 1 933.4948 0.89 20173 13356 2 933.495032 467.7547 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2961.4 - 698431 - - - 0.2785 - 1.382 0.37 - 230.4 1 2 0 0.0003 7 0 0 0 2.43E+08 2.74E+08 - - - 2.7989 0.9811 230117_WJC_METTL3_WT_vs_EV_F03.13362.13362.2 0.0107 12-Jul R.VVFQEFR.Q sp|P35579|MYH9_HUMAN 1 923.4865 0.89 20175 13362 2 923.492493 462.7505 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2962.2 - 1.10E+06 - - - 6.4874 - 1.275 0.347 - 186.5 1 2 0 0.006 7 0 0 0 2.44E+08 2.74E+08 - - - 2.3718 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.13369.13369.2 0.000115 24-Sep K.VIDPATATSVDLR.D sp|P50991|TCPD_HUMAN 1 1356.7249 999 20179 13369 2 1356.732181 679.3697 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 2963.1 - 106016 - - - 5.3703 - 1.642 0.453 - 108.1 1 2 0 0.0073 13 0 0 0 1.04E+07 0.00E+00 - - - 3.6574 0.9944 230117_WJC_METTL3_WT_vs_EV_F03.13381.13381.2 0.0512 14-Jul R.LLSTYLER[166.11].Y "sp|Q12769|NU160_HUMAN,tr|G3V198|G3V198_HUMAN" 2 1003.5578 1.25 20183 13381 2 1003.561615 502.7862 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 6 2964.8 - 1.13E+06 - - - 3.8354 - 1.489 0.213 - 139.1 1 2 0 0.0038 8 0 0 0 6.45E+07 5.15E+07 - - - 1.8137 0.9573 230117_WJC_METTL3_WT_vs_EV_F03.13384.13384.2 1.47 14-Apr R.LFVGSIPK[136.11].S "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 867.5309 0.9 20185 13384 2 867.532932 434.7727 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.75 2965.1 - 2.18E+06 - - - 2.2962 - 1.072 0.141 - 36.9 28 2 0 0.002 8 0 0 0 1.33E+09 1.47E+09 - - - -0.355 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.13398.13398.2 0.0393 12-Jul R.YLLAMER.H "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 894.4633 3.42 20192 13398 2 894.464452 448.2389 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 2966.9 - 745054 - - - 1.2611 - 1.405 0.241 - 172.6 1 2 0 0.0011 7 0 0 0 3.98E+07 1.16E+07 - - - 1.8981 0.9927 230117_WJC_METTL3_WT_vs_EV_F03.13410.13410.2 0.443 12-Jun K.IFTFAEK[136.11].Y "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 4 862.468 0.85 20198 13410 2 862.467593 432.2413 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 6 2968.3 - 1.30E+06 - - - -0.4777 - 1.246 0.197 - 71.8 1 2 0 -0.0004 7 0 0 0 5.14E+07 6.03E+07 - - - 1.1928 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.13412.13412.2 0.0368 22-Jun R.LLSASPVDAAIR[166.11].V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1221.6957 5.01 20199 13412 2 1221.697961 611.8551 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 5.84 2968.5 - 68150.2 - - - 1.8859 - 1.29 0.304 - 75.8 1 2 0 0.0023 12 0 0 0 7.38E+06 1.47E+06 - - - 1.9556 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.13416.13416.2 0.274 12-Jun R.EALGLLR[166.11].A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 780.4733 1.08 20201 13416 2 780.474802 391.2439 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2968.9 - 2.24E+06 - - - 1.9142 - 1.305 0.189 - 135.9 1 2 0 0.0015 7 0 0 0 2.30E+08 2.12E+08 - - - 1.28 0.9958 230117_WJC_METTL3_WT_vs_EV_F03.13417.13417.2 0.877 12-Jun R.EALGLLR.A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 770.465 1.09 20202 13417 2 770.46662 386.2398 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2969 - 1.83E+06 - - - 2.0533 - 1.244 0.2 - 152.6 1 2 0 0.0016 7 0 0 0 2.31E+08 2.12E+08 - - - 1.2095 0.9684 230117_WJC_METTL3_WT_vs_EV_F03.13420.13420.2 1.56 16-Jun R.MPVGSPLLR[166.11].D "sp|Q9NVS2|RT18A_HUMAN,tr|Q5QPA5|Q5QPA5_HUMAN" 2 978.556 1.63 20203 13420 2 978.555992 490.2853 "39S ribosomal protein S18a, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18A PE=1 SV=1" 9.5 2969.4 - 488724 - - - 0 - 1.196 0.1 - 62.9 6 2 0 0 9 0 0 0 8.76E+07 5.36E+07 - - - -0.0502 0.9441 230117_WJC_METTL3_WT_vs_EV_F03.13426.13426.2 0.0621 12-Sep K.PSVYFIK[136.11].F "sp|Q99865|SPI2A_HUMAN,sp|Q56A73|SPIN4_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 9 860.4887 0.49 20205 13426 2 860.48999 431.2516 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 9.01 2970.2 - 1.88E+06 - - - 1.4515 - 1.467 0.333 - 201.7 1 1 0 0.0012 7 0 0 0 2.79E+08 5.66E+08 - - - 2.7144 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.13429.13429.2 0.076 12-Jul R.LMFAVEK[136.11].S sp|Q5SWX8|ODR4_HUMAN 1 844.4608 0.97 20206 13429 2 844.461233 423.2377 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 6 2970.6 - 469468 - - - 0.4997 - 1.408 0.254 - 109.8 1 2 0 0.0004 7 0 0 0 4.63E+07 4.77E+07 - - - 2.0011 0.9843 230117_WJC_METTL3_WT_vs_EV_F03.13430.13430.2 0.038 16-Aug K.LLNYAPLEK.- sp|P62875|RPAB5_HUMAN 1 1059.5964 1.19 20207 13430 2 1059.603466 530.8055 "DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1" 6 2970.7 - 335836 - - - 6.6242 - 1.609 0.306 - 172.6 1 2 0 0.007 9 0 0 0 2.05E+07 1.72E+07 - - - 2.6749 0.9935 230117_WJC_METTL3_WT_vs_EV_F03.13445.13445.2 0.175 12-Aug K.QLLYLEK.Y "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 3 905.5222 1.04 20215 13445 2 905.523391 453.7684 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 6 2972.5 - 1.44E+06 - - - 1.2943 - 1.313 0.119 - 206.3 1 2 0 0.0012 7 0 0 0 7.02E+07 6.77E+07 - - - 0.7824 0.999 230117_WJC_METTL3_WT_vs_EV_F03.13452.13452.2 0.0957 16-Aug R.IVDPEIALK.L "sp|P33240|CSTF2_HUMAN,tr|A0A0A0MT56|A0A0A0MT56_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 996.5855 2.87 20220 13452 2 996.58724 499.3001 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.37 2973.1 - 1.40E+06 - - - 1.6978 - 1.576 0.274 - 127.3 1 2 0 0.0017 9 0 0 0 9.38E+08 3.27E+08 - - - 2.3803 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.13454.13454.2 0.00072 20-Aug K.QAGVFEPTIVK.V "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1187.655 77.02 20222 13454 2 1187.658737 594.8348 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2973.4 - 217610 - - - 3.1263 - 1.605 0.404 - 215.2 1 2 0 0.0037 11 0 0 0 1.77E+07 2.30E+05 - - - 3.3037 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.13469.13469.2 0.0115 16-Jul K.VVLLTEVDK.L sp|P40938|RFC3_HUMAN 1 1014.5961 1.75 20229 13469 2 1014.595936 508.3053 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 4.37 2975.3 - 502214 - - - -0.1735 - 1.493 0.324 - 110.6 1 2 0 -0.0002 9 0 0 0 5.21E+07 2.99E+07 - - - 2.5935 0.9921 230117_WJC_METTL3_WT_vs_EV_F03.13476.13476.2 3.83 14-Sep K.IADFGLAR[166.11].L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 871.4791 1.98 20232 13476 2 871.479467 436.7468 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2976.3 - 1.20E+06 - - - 0.3959 - 1.419 0.093 - 262.7 1 2 0 0.0003 8 0 0 0 9.32E+08 4.71E+08 - - - 0.7832 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.13482.13482.2 0.014 16-Sep K.VVLLTEVDK[136.11].L sp|P40938|RFC3_HUMAN 1 1022.6103 1.75 20235 13482 2 1022.611351 512.3124 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 4.37 2977 - 578220 - - - 1.016 - 1.825 0.378 - 301.5 1 2 0 0.001 9 0 0 0 5.21E+07 2.99E+07 - - - 3.573 0.9752 230117_WJC_METTL3_WT_vs_EV_F03.13484.13484.2 0.167 12-Sep K.PSVYFIK.F "sp|Q99865|SPI2A_HUMAN,sp|Q56A73|SPIN4_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 9 852.4745 0.49 20237 13484 2 852.474919 427.2445 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 9.01 2977.1 - 7.06E+06 - - - 0.4434 - 2.077 0.413 - 285.6 1 1 0 0.0004 7 0 0 0 2.79E+08 5.66E+08 - - - 4.4073 0.9925 230117_WJC_METTL3_WT_vs_EV_F03.13497.13497.2 0.307 12-Jul R.FILIQNR.A "sp|P53680|AP2S1_HUMAN,tr|M0R0N4|M0R0N4_HUMAN,tr|X6R390|X6R390_HUMAN,tr|M0QYZ2|M0QYZ2_HUMAN" 4 902.5338 1.04 20243 13497 2 902.532854 452.2742 AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2 9.75 2978.7 - 1.10E+06 - - - -1.0338 - 1.368 0.193 - 149.6 1 2 0 -0.0009 7 0 0 0 4.11E+07 3.94E+07 - - - 1.4591 0.9761 230117_WJC_METTL3_WT_vs_EV_F03.13512.13512.2 0.825 14-Aug K.IADFGLAR.L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 861.4709 1.97 20251 13512 2 861.467391 431.7427 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2980.4 - 1.27E+07 - - - -4.0175 - 1.623 0.215 - 155.8 1 2 0 -0.0035 8 0 0 0 9.26E+08 4.71E+08 - - - 2.0885 1 230117_WJC_METTL3_WT_vs_EV_F03.13518.13518.2 0.000597 16-Nov K.PLYVALAQR[166.11].K "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PIK9|A0A6I8PIK9_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 25 1039.6054 1.11 20254 13518 2 1039.606306 520.81 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.18 2981.2 - 942248 - - - 0.8859 - 2.149 0.496 - 501.3 1 1 0 0.0009 9 0 0 0 3.98E+08 3.60E+08 - - - 4.9174 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.13521.13521.2 0.0744 14-Aug K.LLQLVEDR.G "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 984.5604 0.49 20255 13521 2 984.561647 493.2875 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 2981.6 - 1.96E+06 - - - 1.2716 - 1.613 0.244 - 200.1 1 2 0 0.0013 8 0 0 0 1.51E+08 3.08E+08 - - - 2.2847 0.9926 230117_WJC_METTL3_WT_vs_EV_F03.13523.13523.2 0.0943 12-Jun R.YFEPLVK.K "sp|Q7L590|MCM10_HUMAN,tr|Q5T670|Q5T670_HUMAN" 2 894.4851 3.6 20257 13523 2 894.484585 448.2498 Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2 6 2981.8 - 551539 - - - -0.5813 - 1.235 0.207 - 98.6 1 2 0 -0.0005 7 0 0 0 1.05E+08 2.92E+07 - - - 1.2385 0.9957 230117_WJC_METTL3_WT_vs_EV_F03.13553.13553.2 4.11 14-Aug K.LAVEAVLR.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 869.5335 7.31 20268 13553 2 869.532331 435.774 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 2985.8 - 9.95E+06 - - - -1.2892 - 1.653 0.21 - 227.8 1 2 0 -0.0011 8 0 0 0 5.86E+09 8.01E+08 - - - 2.1075 0.8595 230117_WJC_METTL3_WT_vs_EV_F03.13554.13554.2 4.37 12-Jun R.FPPYYMR.R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 972.4528 1.52 20269 13554 2 972.45126 487.2337 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 2986 - 1.74E+06 - - - -1.5415 - 0.886 0.119 - 63.6 1 2 0 -0.0015 7 0 0 0 7.29E+07 4.79E+07 - - - -0.4641 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.13571.13571.2 0.0169 14-Aug K.IINDLLAR.S "sp|P51530|DNA2_HUMAN,tr|F8VR31|F8VR31_HUMAN,tr|H0Y455|H0Y455_HUMAN" 3 926.5549 2.65 20277 13571 2 926.554036 464.2847 DNA replication ATP-dependent helicase\nuclease DNA2 OS=Homo sapiens OX=9606 GN=DNA2 PE=1 SV=3 5.84 2988.1 - 850340 - - - -0.9498 - 1.485 0.36 - 137.8 1 2 0 -0.0009 8 0 0 0 2.50E+07 9.44E+06 - - - 2.8922 0.9922 230117_WJC_METTL3_WT_vs_EV_F03.13581.13581.2 0.186 14-Sep R.LLAFAEAR.A "sp|Q8WUY8|NAT14_HUMAN,sp|Q99519|NEUR1_HUMAN,tr|M0R1E3|M0R1E3_HUMAN,tr|E9PIF4|E9PIF4_HUMAN" 4 889.5022 2.23 20281 13581 2 889.501738 445.7584 Probable N-acetyltransferase 14 OS=Homo sapiens OX=9606 GN=NAT14 PE=1 SV=1 6 2989.4 - 1.69E+06 - - - -0.4654 - 1.32 0.171 - 203.2 1 2 0 -0.0004 8 0 0 0 6.05E+07 2.71E+07 - - - 1.1412 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.13582.13582.2 0.116 14-Aug K.LLQPLVPR.Y sp|Q8N8A6|DDX51_HUMAN 1 934.5964 1.06 20282 13582 2 934.59635 468.3055 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2989.6 - 823382 - - - -0.0396 - 1.435 0.242 - 240.2 1 2 0 0 8 0 0 0 9.44E+07 8.91E+07 - - - 1.9177 0.9967 230117_WJC_METTL3_WT_vs_EV_F03.13586.13586.2 0.548 12-Jul K.ILEVDLK[136.11].N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 836.5099 0.86 20283 13586 2 836.509832 419.2622 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2990.1 - 3.86E+06 - - - -0.0454 - 1.588 0.155 - 151.5 1 2 0 0 7 0 0 0 2.84E+08 3.30E+08 - - - 1.6512 0.9845 230117_WJC_METTL3_WT_vs_EV_F03.13591.13591.2 0.0869 14-Jul K.LLQPLVPR[166.11].Y sp|Q8N8A6|DDX51_HUMAN 1 944.6047 1.06 20286 13591 2 944.605238 473.3096 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2990.8 - 1.14E+06 - - - 0.6151 - 1.278 0.064 - 147.8 1 2 0 0.0006 8 0 0 0 9.44E+07 8.91E+07 - - - 0.2533 0.998 230117_WJC_METTL3_WT_vs_EV_F03.13594.13594.2 0.0465 14-Jul K.ILDVMYSR[166.11].L sp|P78527|PRKDC_HUMAN 1 1005.5193 0.99 20288 13594 2 1005.519044 503.7669 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2991.1 - 473703 - - - -0.2267 - 1.416 0.285 - 92.6 1 2 0 -0.0002 8 0 0 0 7.12E+07 7.21E+07 - - - 2.195 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.13603.13603.2 0.000275 12-Aug K.C[160.03]FLTAMR.E "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN" 3 897.4201 1.9 20292 13603 2 897.421274 449.7173 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 8.25 2992.4 - 778949 - - - 1.3316 - 1.465 0.35 - 280.2 1 2 0 0.0012 7 0 0 0 3.77E+07 1.99E+07 - - - 2.8357 0.998 230117_WJC_METTL3_WT_vs_EV_F03.13615.13615.2 0.0142 18-Sep K.QQLLIGAYAK.A sp|Q99832|TCPH_HUMAN 1 1103.6339 17.42 20297 13615 2 1103.633549 552.8242 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.59 2994 - 331393 - - - -0.3135 - 1.309 0.335 - 171.1 1 2 0 -0.0003 10 0 0 0 6.98E+06 4.01E+05 - - - 2.2668 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.13618.13618.2 1.01 12-Jul K.ILEVDLK.N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 828.4957 0.88 20298 13618 2 828.496003 415.2551 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2994.4 - 7.29E+06 - - - 0.4019 - 1.568 0.158 - 152.5 1 2 0 0.0003 7 0 0 0 2.90E+08 3.31E+08 - - - 1.6331 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.13625.13625.2 0.00307 12-Aug K.C[160.03]FLTAMR[166.11].E "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN" 3 907.4283 1.91 20303 13625 2 907.42986 454.7215 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 8.25 2995.3 - 483993 - - - 1.6651 - 1.532 0.394 - 229 1 2 0 0.0015 7 0 0 0 3.77E+07 1.98E+07 - - - 3.3022 0.9946 230117_WJC_METTL3_WT_vs_EV_F03.13640.13640.2 0.031 14-Sep R.DLAPIGIR.V "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 853.5022 1.13 20310 13640 2 853.503438 427.7584 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 5.84 2997.3 - 1.04E+06 - - - 1.5067 - 1.565 0.072 - 303.5 1 2 0 0.0013 8 0 0 0 2.35E+08 2.08E+08 - - - 0.9232 0.9937 230117_WJC_METTL3_WT_vs_EV_F03.13644.13644.2 2.69 12-Jun K.EAVLLLK[136.11].K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 792.52 0.73 20312 13644 2 792.52099 397.2673 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 2997.8 - 1.74E+06 - - - 1.1974 - 1.302 0.155 - 128.5 3 2 0 0.0009 7 0 0 0 6.26E+08 8.54E+08 - - - 0.8086 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.13649.13649.2 0.264 12-Aug K.VLEILGK[136.11].K "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 10 778.5044 2.34 20315 13649 2 778.505748 390.2595 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.97 2998.4 - 421267 - - - 1.7431 - 1.702 0.214 - 167.4 1 2 0 0.0014 7 0 0 0 4.99E+07 2.14E+07 - - - 2.3062 0.996 230117_WJC_METTL3_WT_vs_EV_F03.13655.13655.2 0.685 12-Aug K.EAVLLLK.K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 784.5058 0.73 20318 13655 2 784.506302 393.2602 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 2999.1 - 2.08E+06 - - - 0.5876 - 1.58 0.101 - 269.3 1 2 0 0.0005 7 0 0 0 6.25E+08 8.54E+08 - - - 1.2362 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.13683.13683.2 0.0201 14-Aug R.NLLSVAYK.N "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB2|A2IDB2_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|K7EIT4|K7EIT4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 22 906.5175 1.48 20333 13683 2 906.519989 454.266 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 8.59 3002.6 - 3.96E+06 - - - 2.781 - 1.399 0.252 - 231.1 1 2 0 0.0025 8 0 0 0 4.53E+08 3.07E+08 - - - 1.9141 0.9813 230117_WJC_METTL3_WT_vs_EV_F03.13696.13696.2 4 12-Jul R.LLQIIER[166.11].Y sp|P78527|PRKDC_HUMAN 1 893.5574 1.17 20337 13696 2 893.558567 447.786 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 3004.5 - 6.29E+06 - - - 1.3374 - 1.406 0.008 - 167.8 2 2 0 0.0012 7 0 0 0 2.75E+08 2.36E+08 - - - 0.0449 0.997 230117_WJC_METTL3_WT_vs_EV_F03.13703.13703.2 0.0518 14-Jul K.AAFAPFGR[166.11].L "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 5 845.4423 1.41 20342 13703 2 845.443819 423.7284 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 9.79 3005.3 - 298165 - - - 1.7458 - 1.273 0.221 - 108.9 1 2 0 0.0015 8 0 0 0 2.08E+07 1.48E+07 - - - 1.4008 0.9893 230117_WJC_METTL3_WT_vs_EV_F03.13715.13715.2 0.991 14-Aug K.LALDYGIK[136.11].F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 899.5208 3.19 20349 13715 2 899.52013 450.7677 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 3006.7 - 1.50E+06 - - - -0.7104 - 1.594 0.095 - 149 2 2 0 -0.0006 8 0 0 0 4.48E+08 1.40E+08 - - - 1.0142 0.9945 230117_WJC_METTL3_WT_vs_EV_F03.13722.13722.2 1.55 12-Aug R.LLQIIER.Y sp|P78527|PRKDC_HUMAN 1 883.5491 1.16 20354 13722 2 883.5505 442.7818 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 3007.4 - 8.29E+06 - - - 1.5823 - 1.467 0.089 - 248.2 1 2 0 0.0014 7 0 0 0 2.74E+08 2.36E+08 - - - 0.9122 0.998 230117_WJC_METTL3_WT_vs_EV_F03.13724.13724.2 0.0732 14-Aug K.AAFAPFGR.L "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 5 835.4341 1.5 20356 13724 2 835.435659 418.7243 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 9.79 3007.6 - 835269 - - - 1.8984 - 1.446 0.219 - 233.9 1 2 0 0.0016 8 0 0 0 1.99E+07 1.32E+07 - - - 1.7703 0.9937 230117_WJC_METTL3_WT_vs_EV_F03.13727.13727.2 0.176 16-Jun K.SLTMVALAK.L "sp|P83111|LACTB_HUMAN,tr|H0YNN5|H0YNN5_HUMAN" 2 932.5365 2.6 20359 13727 2 932.537989 467.2755 "Serine beta-lactamase-like protein LACTB, mitochondrial OS=Homo sapiens OX=9606 GN=LACTB PE=1 SV=2" 8.47 3007.9 - 153948 - - - 1.6085 - 1.133 0.192 - 68.1 1 2 0 0.0015 9 0 0 0 7.02E+06 2.70E+06 - - - 0.8199 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.13738.13738.2 0.0476 22-Nov R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 2.24 20365 13738 2 1343.710223 672.8615 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 3009.3 - 224711 - - - 1.2704 - 2.017 0.331 - 166.5 1 2 0 0.0017 12 0 0 0 1.34E+07 5.96E+06 - - - 3.3313 0.9005 230117_WJC_METTL3_WT_vs_EV_F03.13741.13741.2 0.455 14-Jul F.GPVLNYLR[166.11].H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 940.537 0.81 20366 13741 2 940.538069 471.2758 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3009.7 - 371588 - - - 1.1674 - 1.659 0.202 - 154.6 1 1 0 0.0011 8 0 0 0 3.93E+07 4.84E+07 - - - 2.0593 1 230117_WJC_METTL3_WT_vs_EV_F03.13744.13744.2 0.00013 22-Dec R.TVIIEQSWGSPK[136.11].V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1351.7227 2.24 20369 13744 2 1351.728254 676.8686 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 3010.1 - 241502 - - - 4.097 - 2.261 0.503 - 482.9 1 2 0 0.0055 12 0 0 0 1.34E+07 5.96E+06 - - - 4.9009 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.13748.13748.2 0.0413 14-Aug R.FLGC[160.03]VDIK.D "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 950.4895 1.45 20371 13748 2 950.491366 476.252 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 5.83 3010.7 - 1.19E+06 - - - 1.9222 - 1.454 0.37 - 185 1 2 0 0.0018 8 0 0 0 3.56E+07 2.45E+07 - - - 2.9022 0.966 230117_WJC_METTL3_WT_vs_EV_F03.13760.13760.2 0.000345 18-Nov T.LGSATALMIR[166.11].E "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 1041.588 1.01 20380 13760 2 1041.590442 521.8013 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3012.1 - 166360 - - - 2.3243 - 2.154 0.354 - 287.5 1 1 0 0.0024 10 0 0 0 1.82E+07 1.80E+07 - - - 3.7967 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.13770.13770.2 1.21 12-Jul K.FTAILYR.T "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 882.4963 0.74 20386 13770 2 882.498146 442.2554 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.75 3013.3 - 2.89E+06 - - - 2.0476 - 1.613 0.133 - 217.4 1 2 0 0.0018 7 0 0 0 1.53E+08 2.07E+08 - - - 1.5376 0.996 230117_WJC_METTL3_WT_vs_EV_F03.13775.13775.2 0.0183 16-Aug K.YDGIILPGK.- "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 974.5437 1.34 20391 13775 2 974.547074 488.2791 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.83 3013.8 - 227841 - - - 3.4796 - 1.223 0.311 - 175.3 1 2 0 0.0034 9 0 0 0 3.22E+07 2.39E+07 - - - 1.9194 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.13779.13779.2 0.296 18-Aug K.ILAEESYLYK.H sp|Q9NVX0|HAUS2_HUMAN 1 1227.6387 3.03 20393 13779 2 1227.641246 614.8266 HAUS augmin-like complex subunit 2 OS=Homo sapiens OX=9606 GN=HAUS2 PE=1 SV=1 4.53 3014.3 - 178302 - - - 2.0698 - 1.498 0.222 - 134.2 1 2 0 0.0025 10 0 0 0 5.20E+06 1.72E+06 - - - 1.8079 0.9943 230117_WJC_METTL3_WT_vs_EV_F03.13783.13783.2 0.789 12-Jul K.LVYILNR[166.11].D sp|Q15393|SF3B3_HUMAN 1 899.5468 1.3 20396 13783 2 899.548818 450.7807 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 3014.6 - 5.71E+06 - - - 2.2345 - 1.486 0.098 - 148.3 1 2 0 0.002 7 0 0 0 3.21E+08 2.47E+08 - - - 1.0192 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.13785.13785.2 0.0441 12-Aug K.MSILGVR.S "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|E9PM98|E9PM98_HUMAN,tr|A0A494BZW0|A0A494BZW0_HUMAN" 8 774.4422 1.51 20398 13785 2 774.444054 388.2284 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 9.5 3014.8 - 1.24E+06 - - - 2.4004 - 1.616 0.222 - 229.9 1 2 0 0.0019 7 0 0 0 3.60E+07 2.39E+07 - - - 2.2009 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.13786.13786.2 0.137 14-Aug K.VLVPQIPR[166.11].L sp|Q10469|MGAT2_HUMAN 1 930.589 1.13 20399 13786 2 930.590045 466.3018 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 3014.9 - 940693 - - - 1.1154 - 1.233 0.273 - 159.2 1 2 0 0.001 8 0 0 0 9.41E+07 8.33E+07 - - - 1.6887 0.998 230117_WJC_METTL3_WT_vs_EV_F03.13790.13790.2 0.16 12-Aug K.LVYILNR.D sp|Q15393|SF3B3_HUMAN 1 889.5385 1.3 20400 13790 2 889.540259 445.7765 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 3015.4 - 9.56E+06 - - - 1.9347 - 1.421 0.224 - 264.2 1 2 0 0.0017 7 0 0 0 3.21E+08 2.47E+08 - - - 1.8082 0.9837 230117_WJC_METTL3_WT_vs_EV_F03.13792.13792.2 0.815 12-Jul R.ISPLQFR[166.11].- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 869.4999 3.03 20402 13792 2 869.502069 435.7572 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 3015.5 - 3.35E+06 - - - 2.5428 - 1.283 0.073 - 160.1 1 2 0 0.0022 7 0 0 0 3.83E+08 1.26E+08 - - - 0.3691 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.13793.13793.2 0.0292 14-Sep K.VGVNGFGR.L sp|P04406|G3P_HUMAN 1 804.4242 3.06 20403 13793 2 804.425562 403.2194 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 3015.6 - 1.21E+06 - - - 1.6484 - 1.725 0.398 - 223.3 1 2 0 0.0013 8 0 0 0 4.25E+07 1.39E+07 - - - 3.6246 0.9931 230117_WJC_METTL3_WT_vs_EV_F03.13794.13794.2 0.112 14-Jun K.VLVPQIPR.L sp|Q10469|MGAT2_HUMAN 1 920.5807 1.12 20404 13794 2 920.583032 461.2976 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 3015.7 - 1.12E+06 - - - 2.493 - 1.086 0.228 - 109.7 1 2 0 0.0023 8 0 0 0 9.49E+07 8.46E+07 - - - 0.9731 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.13795.13795.2 0.00121 18-Sep R.YPVNSVNILK.A "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1145.6445 20.09 20405 13795 2 1145.646976 573.8295 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.59 3015.9 - 367455 - - - 2.197 - 1.839 0.394 - 133.7 1 2 0 0.0025 10 0 0 0 1.72E+07 8.57E+05 - - - 3.6508 0.9917 230117_WJC_METTL3_WT_vs_EV_F03.13801.13801.3 0.0952 Aug-36 R.MVNHFIAEFK.R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1234.6169 0.66 20409 13801 3 1234.618881 412.5462 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 3016.5 - 951713 - - - 1.6329 - 1.34 0.201 - 46.2 1 2 0 0.002 10 0 0 0 4.14E+07 6.23E+07 - - - 1.6351 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.13802.13802.2 0.0286 14-Aug K.ITAFIVER.D "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 947.544 0.63 20410 13802 2 947.545024 474.7793 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 6 3016.6 - 1.10E+06 - - - 1.0627 - 1.555 0.294 - 164.4 1 2 0 0.001 8 0 0 0 5.95E+07 9.49E+07 - - - 2.5436 0.9942 230117_WJC_METTL3_WT_vs_EV_F03.13806.13806.2 0.0135 12-Jul R.YYFEGIK[136.11].Q "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN" 3 926.4629 2.54 20412 13806 2 926.460865 464.2387 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 6 3017.1 - 775097 - - - -2.2181 - 1.36 0.324 - 124.5 1 2 0 -0.0021 7 0 0 0 4.84E+07 1.91E+07 - - - 2.4077 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.13816.13816.2 0.0601 14-Sep K.ITAFIVER[166.11].D "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 957.5523 0.71 20418 13816 2 957.55372 479.7834 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 6 3018.2 - 2.08E+06 - - - 1.4965 - 2.002 0.371 - 246.2 1 2 0 0.0014 8 0 0 0 5.93E+07 8.30E+07 - - - 3.8743 0.9913 230117_WJC_METTL3_WT_vs_EV_F03.13818.13818.2 0.695 12-Jul R.ISPLQFR.- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 859.4916 2.96 20419 13818 2 859.492962 430.7531 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 3018.4 - 1.43E+07 - - - 1.5986 - 1.384 0.069 - 232.8 1 2 0 0.0014 7 0 0 0 3.68E+08 1.24E+08 - - - 0.5799 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.13819.13819.2 0.00553 14-Aug R.VIFTSPIK[136.11].A sp|P42285|MTREX_HUMAN 1 911.5572 1.14 20420 13819 2 911.558188 456.7859 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 8.72 3018.5 - 1.24E+06 - - - 1.1343 - 1.474 0.326 - 196.5 1 2 0 0.001 8 0 0 0 1.11E+08 9.75E+07 - - - 2.6186 0.9957 230117_WJC_METTL3_WT_vs_EV_F03.13829.13829.2 24.1 12-Jul R.LVQLLVK.A sp|P14923|PLAK_HUMAN 1 811.5531 17.56 20426 13829 2 811.554781 406.7838 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 8.75 3019.7 - 2.70E+06 - - - 2.0405 - 1.714 0.06 - 117.9 1 2 0 0.0017 7 0 0 0 2.43E+08 1.38E+07 - - - 1.191 0.9647 230117_WJC_METTL3_WT_vs_EV_F03.13830.13830.2 1.81 16-May R.VPPEFLVQR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1093.616 1.27 20427 13830 2 1093.616411 547.8153 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3019.9 - 175668 - - - 0.4215 - 1.093 0.061 - 66.3 1 2 0 0.0005 9 0 0 0 6.07E+07 4.79E+07 - - - -0.2513 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.13838.13838.2 0.00708 14-Sep R.LATEFELR.K sp|A5YKK6|CNOT1_HUMAN 1 977.5182 0.68 20431 13838 2 977.518342 489.7664 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.53 3020.9 - 642501 - - - 0.1494 - 1.924 0.21 - 249.8 1 2 0 0.0001 8 0 0 0 1.78E+07 2.60E+07 - - - 2.5657 0.8551 230117_WJC_METTL3_WT_vs_EV_F03.13856.13856.2 1.08 12-May R.FPPYYMR[166.11].R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 982.461 0.7 20442 13856 2 982.465152 492.2378 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 3023 - 249369 - - - 4.1966 - 0.935 0.097 - 77.1 1 2 0 0.0041 7 0 0 0 1.31E+07 1.88E+07 - - - -0.4568 0.9948 230117_WJC_METTL3_WT_vs_EV_F03.13863.13863.2 0.476 12-Jul R.TIPVVFK.D "sp|P25685|DNJB1_HUMAN,tr|A0A7I2V3K7|A0A7I2V3K7_HUMAN" 2 802.4953 0.65 20446 13863 2 802.497631 402.2549 DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4 8.41 3023.9 - 1.86E+06 - - - 2.9346 - 1.243 0.225 - 165.5 1 2 0 0.0024 7 0 0 0 4.82E+07 7.41E+07 - - - 1.3914 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.13867.13867.2 0.00455 12-Jun K.LFEMAYK.K "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 900.4415 4.52 20448 13867 2 900.442521 451.228 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6 3024.4 - 3.08E+06 - - - 1.105 - 1.383 0.416 - 126.2 1 2 0 0.001 7 0 0 0 1.38E+09 3.07E+08 - - - 3.1407 0.9847 230117_WJC_METTL3_WT_vs_EV_F03.13873.13873.2 0.294 14-Jun R.LPWAVAGR.S sp|Q8NBX0|SCPDL_HUMAN 1 868.4919 2.08 20452 13873 2 868.492253 435.2532 Saccharopine dehydrogenase-like oxidoreductase OS=Homo sapiens OX=9606 GN=SCCPDH PE=1 SV=1 9.75 3025.1 - 963063 - - - 0.3811 - 1.332 0.074 - 110.2 2 2 0 0.0003 8 0 0 0 6.91E+07 3.32E+07 - - - 0.3176 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.13877.13877.2 0.00381 18-Jul K.VLQSALAAIR.H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1040.6342 1.04 20455 13877 2 1040.63567 521.3244 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 3025.5 - 282998 - - - 1.3847 - 1.645 0.356 - 121.8 1 2 0 0.0014 10 0 0 0 3.27E+08 3.15E+08 - - - 3.0593 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.13882.13882.2 0.051 12-May K.LFEMAYK[136.11].K "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 908.4557 4.51 20458 13882 2 908.456762 455.2351 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6 3026.2 - 2.54E+06 - - - 1.1404 - 1.356 0.344 - 89.6 1 2 0 0.001 7 0 0 0 1.38E+09 3.07E+08 - - - 2.5464 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.13886.13886.2 0.000518 12-Aug R.FFTPAIR.Q "sp|Q8TDP1|RNH2C_HUMAN,tr|E9PN81|E9PN81_HUMAN" 2 850.4701 1.18 20460 13886 2 850.470437 426.2423 Ribonuclease H2 subunit C OS=Homo sapiens OX=9606 GN=RNASEH2C PE=1 SV=1 9.75 3026.6 - 1.42E+06 - - - 0.368 - 1.743 0.435 - 207.3 1 2 0 0.0003 7 0 0 0 7.27E+07 6.18E+07 - - - 4.0143 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.13889.13889.2 1.56 18-Sep R.VLAESLGPLR.E sp|Q4KMQ1|TPRN_HUMAN 1 1053.6182 1.28 20463 13889 2 1053.618104 527.8164 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 5.97 3027 - 813326 - - - -0.1338 - 1.689 0.244 - 208.3 1 2 0 -0.0001 10 0 0 0 7.25E+07 5.68E+07 - - - 2.3062 0.9883 230117_WJC_METTL3_WT_vs_EV_F03.13892.13892.2 1.2 20-Jun R.LLADPTGAFGK.E sp|P30044|PRDX5_HUMAN 1 1088.5866 3.51 20466 13892 2 1088.588387 545.3006 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.84 3027.4 - 133956 - - - 1.6324 - 1.185 0.119 - 57.4 1 2 0 0.0018 11 0 0 0 2.89E+07 8.21E+06 - - - 0.3786 0.9956 230117_WJC_METTL3_WT_vs_EV_F03.13895.13895.2 0.0237 18-Aug K.VLQSALAAIR[166.11].H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1050.6425 1.04 20467 13895 2 1050.643401 526.3285 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 3027.8 - 2.03E+06 - - - 0.8585 - 1.991 0.049 - 196.4 3 2 0 0.0009 10 0 0 0 3.27E+08 3.15E+08 - - - 1.1117 0.9962 230117_WJC_METTL3_WT_vs_EV_F03.13902.13902.2 0.202 14-Oct K.IAADILIK.E "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 855.543 1.02 20472 13902 2 855.541852 428.7788 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.84 3028.6 - 622171 - - - -1.2881 - 1.64 0.229 - 194.4 1 2 0 -0.0011 8 0 0 0 1.78E+07 1.74E+07 - - - 2.224 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.13906.13906.2 3.98E-05 16-Sep R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 58046.09 20474 13906 2 1030.592287 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 3029.1 - 3.13E+07 - - - 1.2226 - 1.99 0.288 - 225.2 1 2 0 0.0013 9 0 0 0 6.26E+09 1.08E+05 - - - 3.1586 0.9967 230117_WJC_METTL3_WT_vs_EV_F03.13915.13915.2 0.163 12-Aug R.NLVSYLK.Q "sp|Q96T37|RBM15_HUMAN,sp|Q8NDT2|RB15B_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 5 835.4804 0.74 20479 13915 2 835.480685 418.7475 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 8.59 3030.1 - 752814 - - - 0.3962 - 1.407 0.181 - 194.3 1 2 0 0.0003 7 0 0 0 3.16E+07 4.26E+07 - - - 1.4597 0.9545 230117_WJC_METTL3_WT_vs_EV_F03.13916.13916.2 3.04 14-Jun R.YPEEFALR.D "sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN" 4 1023.5025 0.47 20480 13916 2 1023.505376 512.7585 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.53 3030.3 - 335114 - - - 2.765 - 1.067 0.089 - 80.8 2 2 0 0.0028 8 0 0 0 2.00E+07 4.22E+07 - - - -0.2414 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.13922.13922.2 0.228 18-Oct K.LAEALYIADR[166.11].K "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1143.6163 1.6 20482 13922 2 1143.619146 572.8154 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 3031.1 - 248976 - - - 2.4501 - 2.08 0.114 - 333.6 1 2 0 0.0028 10 0 0 0 6.85E+07 4.28E+07 - - - 1.9264 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.13926.13926.2 0.0921 18-Sep K.LAEALYIADR.K "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1133.6081 0.73 20484 13926 2 1133.608649 567.8113 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 3031.6 - 443590 - - - 0.5072 - 2.196 0.295 - 292.2 1 2 0 0.0006 10 0 0 0 7.68E+07 1.05E+08 - - - 3.4154 0.9902 230117_WJC_METTL3_WT_vs_EV_F03.13931.13931.2 0.0616 14-May R.DVPLPVVR.V "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 893.5335 0.43 20487 13931 2 893.534303 447.774 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.84 3032.1 - 954636 - - - 0.9524 - 1.001 0.217 - 70.2 2 2 0 0.0009 8 0 0 0 4.01E+07 9.23E+07 - - - 0.512 0.9599 230117_WJC_METTL3_WT_vs_EV_F03.13938.13938.2 1.06 12-Jun K.TISLVIR[166.11].G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 810.5203 1.35 20490 13938 2 810.520498 406.2674 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 9.41 3033.1 - 585245 - - - 0.2949 - 1.145 0.031 - 97.2 1 2 0 0.0002 7 0 0 0 5.96E+07 4.41E+07 - - - -0.3011 0.9597 230117_WJC_METTL3_WT_vs_EV_F03.13942.13942.2 0.296 20-Apr K.VMPTLAPVVAK.L sp|Q8IWI9|MGAP_HUMAN 1 1124.6628 1.27 20492 13942 2 1124.662299 563.3387 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 8.72 3033.6 - 105013 - - - -0.4028 - 1.147 0.144 - 36 16 2 0 -0.0005 11 0 0 0 6.29E+06 4.95E+06 - - - -0.0624 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.13948.13948.2 0.00332 16-Aug K.FTPGAVMLR.V "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 990.5321 1.61 20493 13948 2 990.535659 496.2733 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.75 3034.6 - 603232 - - - 3.6213 - 1.592 0.382 - 207.2 1 2 0 0.0036 9 0 0 0 4.96E+07 3.07E+07 - - - 3.2066 0.998 230117_WJC_METTL3_WT_vs_EV_F03.13953.13953.2 0.00235 28-Jun K.NQVALNPQNTVFDAK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1657.8424 999 20495 13953 2 1657.840345 829.9285 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3035.3 - 142876 - - - -1.2299 - 1.438 0.398 - 37.9 1 2 0 -0.002 15 0 0 0 5.21E+06 0.00E+00 - - - 2.8731 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.13961.13961.2 0.000251 14-Aug R.VLVLVPTR[166.11].E "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 905.5938 0.9 20498 13961 2 905.594031 453.8042 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 9.72 3036.4 - 2.31E+06 - - - 0.3015 - 1.762 0.212 - 261.2 1 2 0 0.0003 8 0 0 0 8.00E+07 8.90E+07 - - - 2.3151 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.13963.13963.2 2.30E-05 14-Aug R.VLVLVPTR.E "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 895.5855 0.9 20500 13963 2 895.586207 448.8 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 9.72 3036.6 - 2.07E+06 - - - 0.8028 - 1.78 0.366 - 228.3 1 2 0 0.0007 8 0 0 0 8.00E+07 8.91E+07 - - - 3.4831 0.8962 230117_WJC_METTL3_WT_vs_EV_F03.13966.13966.2 0.12 12-May K.SAEFLLH.M "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 815.4178 - 20501 13966 2 815.418827 408.7162 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 5.22 3037 - 2.51E+06 - - - 1.3159 - 1.309 0.286 - 131.8 1 1 0 0.0011 7 0 0 0 - - - - - 2.0062 0.9565 230117_WJC_METTL3_WT_vs_EV_F03.13972.13972.2 0.00362 12-Jun R.LFVLTTK.N sp|Q96RS6|NUDC1_HUMAN 1 820.5058 2.74 20504 13972 2 820.510356 411.2602 NudC domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NUDCD1 PE=1 SV=2 8.75 3037.7 - 309866 - - - 5.5027 - 1.425 0.119 - 104.7 1 2 0 0.0045 7 0 0 0 3.76E+07 1.37E+07 - - - 1.0407 0.9793 230117_WJC_METTL3_WT_vs_EV_F03.13981.13981.2 0.713 14-Apr K.LFVADLQR[166.11].V sp|Q92830|KAT2A_HUMAN 1 970.5475 7.44 20510 13981 2 970.54865 486.281 Histone acetyltransferase KAT2A OS=Homo sapiens OX=9606 GN=KAT2A PE=1 SV=3 5.84 3038.7 - 308216 - - - 1.1478 - 1.158 0.155 - 27.5 28 2 0 0.0011 8 0 0 0 8.62E+07 1.16E+07 - - - -0.0185 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.13985.13985.2 0.00746 14-Aug R.LPLATIVK.D sp|O94776|MTA2_HUMAN 1 853.5637 1.51 20512 13985 2 853.564948 427.7891 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 3039.2 - 779840 - - - 1.4738 - 1.613 0.361 - 140 1 2 0 0.0013 8 0 0 0 2.90E+08 1.91E+08 - - - 3.1489 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.13987.13987.2 0.0761 18-Aug K.NLQEAEEWYK[136.11].S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1316.6128 1.88 20514 13987 2 1316.613969 659.3137 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3039.5 - 142870 - - - 0.8636 - 1.377 0.24 - 114.3 1 2 0 0.0011 10 0 0 0 2.20E+07 1.17E+07 - - - 1.7062 0.9878 230117_WJC_METTL3_WT_vs_EV_F03.13992.13992.2 1.27 16-Jun K.FTPGAVMLR[166.11].V "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1000.5403 1.92 20516 13992 2 1000.542311 501.2774 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.75 3040.2 - 756088 - - - 1.9679 - 1.243 0.117 - 104 2 2 0 0.002 9 0 0 0 4.65E+07 2.42E+07 - - - 0.3994 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.13999.13999.2 0.0452 14-Sep R.VWAEYALK[136.11].R sp|Q6P2Q9|PRP8_HUMAN 1 986.5317 1.27 20521 13999 2 986.533319 494.2731 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3041 - 1.84E+06 - - - 1.6735 - 1.617 0.317 - 331.2 1 2 0 0.0017 8 0 0 0 2.70E+08 2.12E+08 - - - 2.8312 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.14000.14000.2 0.0512 14-Aug R.EAVLSLYR.A sp|L0R8F8|MIDUO_HUMAN 1 949.5233 1.02 20522 14000 2 949.524686 475.7689 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 6.1 3041.1 - 1.89E+06 - - - 1.4786 - 1.458 0.261 - 200.7 1 2 0 0.0014 8 0 0 0 5.61E+07 5.51E+07 - - - 2.1055 0.9957 230117_WJC_METTL3_WT_vs_EV_F03.14011.14011.2 0.132 14-Jul K.LYLADPMK.A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 949.4943 1.57 20528 14011 2 949.493331 475.7544 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 3042.5 - 2.39E+06 - - - -1.01 - 1.34 0.273 - 141 1 2 0 -0.001 8 0 0 0 3.33E+08 2.12E+08 - - - 1.9398 1 230117_WJC_METTL3_WT_vs_EV_F03.14019.14019.2 1.41E-05 18-Dec R.VPLVAPEDLR[166.11].D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1117.6371 0.5 20530 14019 2 1117.639131 559.8258 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3043.6 - 1.03E+06 - - - 1.836 - 2.466 0.421 - 693.9 1 2 0 0.0021 10 0 0 0 9.20E+08 1.84E+09 - - - 4.6693 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.14020.14020.2 0.216 18-Nov R.VPLVAPEDLR.D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1107.6288 0.5 20531 14020 2 1107.630264 554.8217 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3043.7 - 382047 - - - 1.3136 - 2.247 0.314 - 532.4 1 2 0 0.0015 10 0 0 0 9.20E+08 1.84E+09 - - - 3.6196 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.14029.14029.2 0.00356 14-Aug K.LYLADPMK[136.11].A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 957.5085 1.58 20534 14029 2 957.508023 479.7615 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 3045 - 3.50E+06 - - - -0.4877 - 1.634 0.392 - 203.3 1 2 0 -0.0005 8 0 0 0 3.34E+08 2.12E+08 - - - 3.4171 0.8685 230117_WJC_METTL3_WT_vs_EV_F03.14037.14037.2 1.14 12-Jul H.EPLGLLR.G sp|Q5W0U4|BSPRY_HUMAN 1 796.4807 4.25 20539 14037 2 796.481276 399.2476 B box and SPRY domain-containing protein OS=Homo sapiens OX=9606 GN=BSPRY PE=2 SV=1 6.1 3045.9 - 2.53E+06 - - - 0.737 - 1.464 0.215 - 233.9 1 1 0 0.0006 7 0 0 0 1.46E+08 3.44E+07 - - - 1.8366 1 230117_WJC_METTL3_WT_vs_EV_F03.14064.14064.2 9.29E-06 20-Dec K.YFVEAGAMAVR.R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1212.5961 10.05 20551 14064 2 1212.600427 607.3053 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3049.5 - 590251 - - - 3.5445 - 2.208 0.542 - 541.2 1 2 0 0.0043 11 0 0 0 9.29E+08 9.24E+07 - - - 5.1856 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.14065.14065.2 0.00285 20-Jun K.YFVEAGAMAVR[166.11].R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1222.6044 10.07 20552 14065 2 1222.609046 612.3095 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3049.7 - 84226.2 - - - 3.8009 - 1.258 0.381 - 120.6 1 2 0 0.0046 11 0 0 0 9.26E+08 9.20E+07 - - - 2.4745 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.14080.14080.2 5.57E-06 26-Sep K.IFVGGLSPDTPEEK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1487.7508 1.35 20563 14080 2 1487.746405 744.8827 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3051.6 - 187592 - - - -2.9373 - 1.911 0.464 - 77.5 1 2 0 -0.0044 14 0 0 0 9.83E+06 7.26E+06 - - - 4.0919 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.14088.14088.2 8.65E-05 26-Sep K.IFVGGLSPDTPEEK[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1495.765 1.35 20566 14088 2 1495.764111 748.8898 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3052.6 - 266103 - - - -0.5776 - 1.609 0.529 - 124.8 1 2 0 -0.0009 14 0 0 0 9.83E+06 7.26E+06 - - - 4.1414 0.9916 230117_WJC_METTL3_WT_vs_EV_F03.14099.14099.2 0.223 12-Aug K.IAWALSR.K sp|Q04760|LGUL_HUMAN 1 815.4654 1.11 20572 14099 2 815.465643 408.74 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 9.75 3053.8 - 943000 - - - 0.3311 - 1.527 0.051 - 203.9 1 2 0 0.0003 7 0 0 0 1.24E+08 1.12E+08 - - - 0.7589 0.983 230117_WJC_METTL3_WT_vs_EV_F03.14104.14104.2 0.0961 16-Jul R.VPPEFLVQR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1093.616 1.53 20575 14104 2 1093.621783 547.8153 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3054.4 - 236916 - - - 5.3337 - 1.166 0.305 - 147.5 1 2 0 0.0058 9 0 0 0 5.08E+07 3.33E+07 - - - 1.7362 0.9969 230117_WJC_METTL3_WT_vs_EV_F03.14105.14105.2 0.25 12-Aug R.SLEVILR[166.11].A sp|Q14566|MCM6_HUMAN 1 838.5152 1.22 20576 14105 2 838.516575 420.2649 DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1 5.72 3054.5 - 762505 - - - 1.672 - 1.427 0.164 - 178.2 1 2 0 0.0014 7 0 0 0 6.14E+07 5.02E+07 - - - 1.3785 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.14108.14108.2 0.0912 12-Aug R.VFDMLNR[166.11].R "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 12 903.4512 1.61 20578 14108 2 903.45296 452.7329 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3054.9 - 1.33E+06 - - - 1.9558 - 1.728 0.417 - 262.3 1 2 0 0.0018 7 0 0 0 7.43E+07 4.63E+07 - - - 3.8535 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.14111.14111.2 0.00647 18-Oct R.VPYVIISAAK.G "sp|P28340|DPOD1_HUMAN,tr|M0QXQ2|M0QXQ2_HUMAN,tr|M0QXE6|M0QXE6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 5 1059.6328 0.59 20581 14111 2 1059.633772 530.8237 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.56 3055.2 - 373757 - - - 0.8871 - 1.964 0.364 - 281.7 1 2 0 0.0009 10 0 0 0 1.17E+07 1.98E+07 - - - 3.6133 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.14114.14114.2 0.0425 12-Jun R.FTDILVR[166.11].H sp|O43143|DHX15_HUMAN 1 872.4995 1.08 20583 14114 2 872.50012 437.257 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 3055.6 - 1.26E+07 - - - 0.6842 - 1.342 0.315 - 111 1 2 0 0.0006 7 0 0 0 5.97E+08 5.52E+08 - - - 2.2995 0.9727 230117_WJC_METTL3_WT_vs_EV_F03.14116.14116.2 10.3 14-Jul K.LLGPVLVK.Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 837.5688 3.85 20584 14116 2 837.569161 419.7917 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 3055.9 - 1.61E+06 - - - 0.4609 - 1.239 0.03 - 85.7 1 2 0 0.0004 8 0 0 0 1.10E+09 2.86E+08 - - - -0.0912 0.9778 230117_WJC_METTL3_WT_vs_EV_F03.14134.14134.2 3.65 14-Aug K.LLGPVLVK[136.11].Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 845.583 3.85 20593 14134 2 845.58359 423.7988 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 3058.2 - 2.46E+06 - - - 0.7273 - 1.187 0.058 - 109.8 1 2 0 0.0006 8 0 0 0 1.10E+09 2.86E+08 - - - -0.0138 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.14139.14139.2 0.00544 12-Aug R.FTDILVR.H sp|O43143|DHX15_HUMAN 1 862.4913 1.08 20596 14139 2 862.492738 432.2529 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 3058.7 - 4.26E+06 - - - 1.7218 - 1.518 0.335 - 249.6 1 2 0 0.0015 7 0 0 0 5.97E+08 5.52E+08 - - - 2.8374 0.9916 230117_WJC_METTL3_WT_vs_EV_F03.14140.14140.2 0.723 12-Jul R.SLILAMK[136.11].A sp|Q7Z353|HDX_HUMAN 1 782.4815 0.5 20597 14140 2 782.483035 392.248 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 8.47 3058.8 - 1.15E+06 - - - 1.9016 - 1.245 0.124 - 199.6 1 2 0 0.0015 7 0 0 0 1.89E+07 3.80E+07 - - - 0.6507 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.14141.14141.2 0.0667 22-Dec K.SPILVATAVAAR[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1177.7058 1.11 20598 14141 2 1177.705441 589.8602 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3059 - 301467 - - - -0.3286 - 2.404 0.34 - 390.9 1 2 0 -0.0004 12 0 0 0 7.04E+08 6.35E+08 - - - 3.86 0.8759 230117_WJC_METTL3_WT_vs_EV_F03.14146.14146.2 0.0668 16-Jul L.LADSMVALR.T "sp|Q9GZW8|MS4A7_HUMAN,tr|E9PN40|E9PN40_HUMAN,tr|E9PIV6|E9PIV6_HUMAN" 3 974.5219 0.14 20601 14146 2 974.521879 488.2682 Membrane-spanning 4-domains subfamily A member 7 OS=Homo sapiens OX=9606 GN=MS4A7 PE=1 SV=1 5.84 3059.6 - 349570 - - - -0.0226 - 1.659 0.23 - 98.1 1 1 0 0 9 0 0 0 1.93E+07 1.38E+08 - - - 2.2043 0.963 230117_WJC_METTL3_WT_vs_EV_F03.14156.14156.2 7.69 18-May K.LFPGSPAIYK.L "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|F8W705|F8W705_HUMAN,tr|C9JF75|C9JF75_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|C9J6W1|C9J6W1_HUMAN,tr|H0YBN8|H0YBN8_HUMAN,tr|C9J1W9|C9J1W9_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 17 1091.6015 10.71 20606 14156 2 1091.602813 546.808 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 8.59 3061 - 144435 - - - 1.1735 - 1.022 0.11 - 51.4 5 2 0 0.0013 10 0 0 0 4.09E+07 3.82E+06 - - - -0.3984 0.9967 230117_WJC_METTL3_WT_vs_EV_F03.14162.14162.2 0.352 14-Aug R.VPDVVLIK.K "sp|Q96D46|NMD3_HUMAN,tr|C9JA08|C9JA08_HUMAN" 2 881.5586 2.73 20610 14162 2 881.55924 441.7866 60S ribosomal export protein NMD3 OS=Homo sapiens OX=9606 GN=NMD3 PE=1 SV=1 5.81 3061.8 - 407534 - - - 0.7203 - 1.118 0.269 - 124.2 1 2 0 0.0006 8 0 0 0 4.09E+07 1.50E+07 - - - 1.364 0.9922 230117_WJC_METTL3_WT_vs_EV_F03.14166.14166.2 0.547 12-Jun R.LILPYER.F "sp|Q14865|ARI5B_HUMAN,tr|A0A7P0TAD2|A0A7P0TAD2_HUMAN" 2 902.5226 1.74 20612 14166 2 902.523675 452.2686 AT-rich interactive domain-containing protein 5B OS=Homo sapiens OX=9606 GN=ARID5B PE=1 SV=3 6 3062.3 - 457281 - - - 1.2432 - 1.167 0.151 - 119 1 2 0 0.0011 7 0 0 0 1.99E+07 1.14E+07 - - - 0.6453 1 230117_WJC_METTL3_WT_vs_EV_F03.14172.14172.2 7.70E-05 14/22 K.SPILVATAVAAR.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1167.6976 1.11 20616 14172 2 1167.699511 584.8561 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3063 - 1.75E+06 - - - 1.6725 - 2.598 0.533 - 833.4 1 2 0 0.002 12 0 0 0 7.04E+08 6.35E+08 - - - 5.4892 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.14173.14173.2 0.139 14-Aug K.GIGLAIVR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 807.5206 0.93 20617 14173 2 807.521132 404.7676 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 3063.1 - 400532 - - - 0.6675 - 1.388 0.287 - 174.4 1 2 0 0.0005 8 0 0 0 5.19E+08 5.61E+08 - - - 2.1494 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.14174.14174.2 0.00462 16-Aug K.VLPLEEAYR.F sp|Q9H223|EHD4_HUMAN 1 1088.5866 2.06 20618 14174 2 1088.589008 545.3006 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 3063.3 - 310474 - - - 2.2029 - 1.547 0.366 - 209.1 1 2 0 0.0024 9 0 0 0 2.30E+08 1.11E+08 - - - 3.0058 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.14180.14180.2 0.0434 12-Jul R.AWGALIK[136.11].E "sp|Q53F19|NCBP3_HUMAN,tr|K7ELP6|K7ELP6_HUMAN" 2 765.4629 0.06 20620 14180 2 765.464311 383.7387 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 8.8 3064.1 - 1.62E+06 - - - 1.8956 - 1.426 0.268 - 162.3 1 2 0 0.0015 7 0 0 0 2.53E+06 4.08E+07 - - - 2.1444 0.9894 230117_WJC_METTL3_WT_vs_EV_F03.14181.14181.2 1.03 14-Jul R.MLQAMGWK.E sp|P98175|RBM10_HUMAN 1 963.467 0.56 20621 14181 2 963.470132 482.7408 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 8.5 3064.2 - 416596 - - - 3.2207 - 1.122 0.213 - 93.8 1 2 0 0.0031 8 0 0 0 8.39E+06 1.49E+07 - - - 0.9604 0.9965 230117_WJC_METTL3_WT_vs_EV_F03.14182.14182.2 0.895 14-Jul R.LLAMLEQK.N "sp|Q96EA4|SPDLY_HUMAN,tr|H0YBG5|H0YBG5_HUMAN" 2 944.5365 11.5 20622 14182 2 944.536532 473.2755 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 6 3064.3 - 945563 - - - 0.0455 - 1.386 0.205 - 101 1 2 0 0 8 0 0 0 3.57E+07 3.11E+06 - - - 1.5396 0.9948 230117_WJC_METTL3_WT_vs_EV_F03.14205.14205.2 0.587 14-Jul R.LLLIATGK.R "sp|Q9NQW6|ANLN_HUMAN,tr|H7C1K5|H7C1K5_HUMAN" 2 827.548 0.05 20637 14205 2 827.547858 414.7813 Anillin OS=Homo sapiens OX=9606 GN=ANLN PE=1 SV=2 8.75 3067.1 - 953088 - - - -0.2199 - 1.594 0.122 - 129 1 2 0 -0.0002 8 0 0 0 4.48E+07 9.68E+08 - - - 1.3482 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.14236.14236.2 0.0601 12-Jun K.IVQWDIR.S "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 928.5131 5.46 20654 14236 2 928.514594 465.2638 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.84 3070.9 - 508110 - - - 1.6618 - 1.362 0.166 - 106.6 1 2 0 0.0015 7 0 0 0 5.19E+07 9.51E+06 - - - 1.2455 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.14240.14240.2 0.0511 16-Aug K.VLPLEEAYR[166.11].F sp|Q9H223|EHD4_HUMAN 1 1098.5949 2.1 20656 14240 2 1098.595733 550.3047 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 3071.4 - 1.83E+06 - - - 0.7764 - 1.448 0.218 - 238.7 1 2 0 0.0009 9 0 0 0 2.29E+08 1.09E+08 - - - 1.7218 0.999 230117_WJC_METTL3_WT_vs_EV_F03.14243.14243.2 0.00474 14-Jul K.VITMFVQR.Q "sp|P13010|XRCC5_HUMAN,tr|C9JZ81|C9JZ81_HUMAN,tr|H7C0H9|H7C0H9_HUMAN" 3 992.5477 0.85 20659 14243 2 992.550662 497.2811 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 9.72 3071.6 - 482146 - - - 2.9621 - 1.605 0.353 - 146 1 2 0 0.0029 8 0 0 0 1.39E+08 1.63E+08 - - - 3.0743 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.14244.14244.2 0.0516 16-Jul R.VLGVLEVSR.S "sp|Q9H0C8|ILKAP_HUMAN,tr|F8SNU7|F8SNU7_HUMAN,tr|H7C2I8|H7C2I8_HUMAN" 3 970.5811 3.4 20660 14244 2 970.581726 486.2978 Integrin-linked kinase-associated serine\threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1 5.97 3071.8 - 458893 - - - 0.613 - 1.397 0.23 - 92.6 1 2 0 0.0006 9 0 0 0 4.63E+07 1.36E+07 - - - 1.7068 0.9357 230117_WJC_METTL3_WT_vs_EV_F03.14253.14253.2 0.523 14-Jun K.VLLSALER.L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 899.544 2.47 20662 14253 2 899.548598 450.7793 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.97 3073.1 - 512939 - - - 5.0926 - 1.317 0.119 - 73.1 3 2 0 0.0046 8 0 0 0 5.92E+08 2.40E+08 - - - 0.5358 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.14256.14256.2 0.0358 16-Sep R.LAEYYGLYR.D sp|Q96DV4|RM38_HUMAN 1 1146.571 1.2 20664 14256 2 1146.57547 574.2928 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3073.4 - 217542 - - - 3.9335 - 2.008 0.332 - 265.9 1 2 0 0.0045 9 0 0 0 5.39E+07 4.49E+07 - - - 3.5086 0.9917 230117_WJC_METTL3_WT_vs_EV_F03.14260.14260.2 0.0908 14-Jul K.VLLSALER[166.11].L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 909.5523 2.55 20666 14260 2 909.555965 455.7834 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.97 3074 - 553507 - - - 4.0437 - 1.431 0.199 - 121.4 1 2 0 0.0037 8 0 0 0 5.89E+08 2.31E+08 - - - 1.5905 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.14261.14261.2 0.506 14-Aug K.GIGLAIVR.D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 797.5123 0.93 20667 14261 2 797.51347 399.7634 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 3074 - 1.23E+07 - - - 1.4382 - 1.381 0.25 - 214.7 1 2 0 0.0011 8 0 0 0 5.19E+08 5.61E+08 - - - 1.8607 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.14262.14262.2 0.376 16-Sep R.LAEYYGLYR[166.11].D sp|Q96DV4|RM38_HUMAN 1 1156.5792 1.2 20668 14262 2 1156.582258 579.2969 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3074.1 - 197202 - - - 2.6181 - 1.686 0.189 - 286.3 1 2 0 0.003 9 0 0 0 5.39E+07 4.49E+07 - - - 1.9472 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.14266.14266.2 0.236 12-Jul K.LWNGLVK[136.11].V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 836.5 0.95 20670 14266 2 836.50187 419.2573 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 3074.7 - 1.15E+06 - - - 2.2666 - 1.351 0.22 - 99.8 1 2 0 0.0019 7 0 0 0 7.73E+07 8.13E+07 - - - 1.6186 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.14267.14267.2 0.0709 18-Oct K.LPAVVTADLR.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1053.6182 2.25 20671 14267 2 1053.622005 527.8164 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.84 3074.8 - 190219 - - - 3.5687 - 2.113 0.308 - 277.7 1 2 0 0.0038 10 0 0 0 1.33E+08 5.94E+07 - - - 3.4029 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.14280.14280.2 0.00097 16-Jul K.LLVLDPAQR.L sp|P50750|CDK9_HUMAN 1 1023.6077 1.84 20676 14280 2 1023.610384 512.8111 Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3 5.84 3076.6 - 358851 - - - 2.6416 - 1.515 0.326 - 136.9 1 2 0 0.0027 9 0 0 0 4.55E+07 2.47E+07 - - - 2.6498 0.9956 230117_WJC_METTL3_WT_vs_EV_F03.14298.14298.2 0.18 14-Aug K.VLETFLAK.S "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 919.5379 1.45 20688 14298 2 919.540048 460.7762 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 5.97 3078.8 - 757440 - - - 2.3697 - 1.372 0.173 - 174.7 1 2 0 0.0022 8 0 0 0 8.11E+07 5.60E+07 - - - 1.2719 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.14304.14304.2 0.0059 16-Oct K.LNSLAIGLR.Q sp|P54886|P5CS_HUMAN 1 955.5815 1.4 20692 14304 2 955.583756 478.798 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3079.5 - 548409 - - - 2.3975 - 2.187 0.375 - 284.6 1 2 0 0.0023 9 0 0 0 7.08E+07 5.06E+07 - - - 4.0739 0.9778 230117_WJC_METTL3_WT_vs_EV_F03.14305.14305.2 3.54 12-Jun R.FPLVSVR.N "sp|Q8NFF5|FAD1_HUMAN,tr|Q5T196|Q5T196_HUMAN" 2 816.4858 4.48 20693 14305 2 816.487752 409.2502 FAD synthase OS=Homo sapiens OX=9606 GN=FLAD1 PE=1 SV=1 9.75 3079.6 - 545210 - - - 2.4226 - 1.207 0.065 - 80.9 1 2 0 0.002 7 0 0 0 8.19E+07 1.83E+07 - - - 0.1166 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.14311.14311.2 0.00289 16-Oct K.LNSLAIGLR[166.11].Q sp|P54886|P5CS_HUMAN 1 965.5897 1.57 20696 14311 2 965.591536 483.8021 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3080.5 - 652447 - - - 1.8652 - 2.303 0.365 - 309.6 1 2 0 0.0018 9 0 0 0 6.47E+07 4.12E+07 - - - 4.1497 1 230117_WJC_METTL3_WT_vs_EV_F03.14313.14313.2 0.000272 20-Oct K.DAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1160.5561 65.97 20697 14313 2 1160.55765 581.2853 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.92 3080.7 - 374592 - - - 1.3373 - 2.429 0.453 - 326.6 1 2 0 0.0016 11 0 0 0 9.53E+06 1.45E+05 - - - 4.7872 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.14334.14334.2 0.0158 14-Sep K.NIELAVMR.R "sp|O14818|PSA7_HUMAN,tr|H0Y586|H0Y586_HUMAN" 2 944.5113 2.23 20707 14334 2 944.509669 473.2629 Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1 6 3083.4 - 1.31E+06 - - - -1.766 - 1.664 0.296 - 267.9 1 2 0 -0.0017 8 0 0 0 4.50E+07 2.02E+07 - - - 2.7625 0.9714 230117_WJC_METTL3_WT_vs_EV_F03.14336.14336.2 4.22 12-May K.LWNGLVK.V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 828.4858 0.99 20709 14336 2 828.486963 415.2502 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 3083.5 - 955693 - - - 1.4351 - 1.181 0.074 - 49.6 6 2 0 0.0012 7 0 0 0 8.05E+07 8.14E+07 - - - -0.2333 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.14337.14337.2 0.107 12-Aug K.LSAFAFK.Q sp|O75717|WDHD1_HUMAN 1 782.4327 1.72 20710 14337 2 782.434503 392.2236 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 8.75 3083.7 - 746235 - - - 2.335 - 1.574 0.212 - 162.2 1 2 0 0.0018 7 0 0 0 2.80E+07 1.63E+07 - - - 2.0436 0.9922 230117_WJC_METTL3_WT_vs_EV_F03.14338.14338.2 0.428 18-Aug K.IMLVEPPVAK[136.11].V sp|P18583|SON_HUMAN 1 1103.6504 1.76 20711 14338 2 1103.654898 552.8325 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3083.8 - 295859 - - - 4.0728 - 1.473 0.209 - 117.5 1 2 0 0.0045 10 0 0 0 7.49E+07 4.26E+07 - - - 1.6643 0.9316 230117_WJC_METTL3_WT_vs_EV_F03.14342.14342.2 0.00105 12-Aug D.GDFVVLK.R sp|Q9UJA5|TRM6_HUMAN 1 776.4432 1.13 20713 14342 2 776.445393 389.2289 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 OS=Homo sapiens OX=9606 GN=TRMT6 PE=1 SV=1 5.84 3084.3 - 384277 - - - 2.7729 - 1.602 0.338 - 255.1 1 1 0 0.0022 7 0 0 0 1.42E+07 1.26E+07 - - - 3.03 0.9961 230117_WJC_METTL3_WT_vs_EV_F03.14343.14343.2 0.00352 26-Jul K.VPQVSTPTLVEVSR.N "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1510.8355 999 20714 14343 2 1510.842354 756.425 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.97 3084.4 - 204641 - - - 4.5313 - 1.621 0.328 - 120 1 2 0 0.0068 14 0 0 0 2.01E+06 0.00E+00 - - - 2.6736 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.14344.14344.2 5.48E-05 28-Sep R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 0.4 20715 14344 2 1410.786901 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3084.6 - 165519 - - - 2.7098 - 1.837 0.397 - 105.4 1 2 0 0.0038 15 0 0 0 9.04E+06 2.26E+07 - - - 3.4672 0.9847 230117_WJC_METTL3_WT_vs_EV_F03.14350.14350.2 0.687 12-Jun K.LSAFAFK[136.11].Q sp|O75717|WDHD1_HUMAN 1 790.4469 1.71 20718 14350 2 790.449782 396.2307 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 8.75 3085.2 - 703260 - - - 3.6764 - 1.378 0.115 - 74.9 1 2 0 0.0029 7 0 0 0 2.80E+07 1.63E+07 - - - 0.9054 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.14355.14355.2 0.0634 12-Jul R.FLDPEFR.E sp|Q5VUA4|ZN318_HUMAN 1 922.4549 1.5 20721 14355 2 922.456228 462.2347 Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2 4.37 3085.9 - 1.02E+06 - - - 1.4743 - 1.305 0.288 - 168.2 1 2 0 0.0014 7 0 0 0 4.92E+07 3.28E+07 - - - 2.0112 0.9799 230117_WJC_METTL3_WT_vs_EV_F03.14356.14356.2 0.827 12-Jun R.FLDPEFR[166.11].E sp|Q5VUA4|ZN318_HUMAN 1 932.4631 1.56 20722 14356 2 932.464802 467.2388 Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2 4.37 3085.9 - 738939 - - - 1.7845 - 1.004 0.132 - 112.3 1 2 0 0.0017 7 0 0 0 4.93E+07 3.17E+07 - - - 0.0281 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.14365.14365.2 0.0231 16-Sep R.ILALDC[160.03]GLK[136.11].Y "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1009.5722 2.06 20728 14365 2 1009.574347 505.7934 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.83 3087.1 - 2.49E+06 - - - 2.1732 - 1.8 0.257 - 201.6 1 2 0 0.0022 9 0 0 0 1.28E+08 6.21E+07 - - - 2.639 0.9927 230117_WJC_METTL3_WT_vs_EV_F03.14380.14380.2 2.09 14-Jul K.ALYPVIPR[166.11].D sp|Q8TCS8|PNPT1_HUMAN 1 937.5625 2.47 20736 14380 2 937.564197 469.7885 "Polyribonucleotide nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PNPT1 PE=1 SV=2" 8.79 3089 - 490830 - - - 1.8548 - 1.274 0.132 - 141.6 1 2 0 0.0017 8 0 0 0 6.52E+07 2.64E+07 - - - 0.7458 1 230117_WJC_METTL3_WT_vs_EV_F03.14381.14381.2 1.83E-05 18-Oct R.IATANMLGIR.K sp|Q9NX20|RM16_HUMAN 1 1058.5907 1.07 20737 14381 2 1058.59374 530.3026 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3089.1 - 521514 - - - 2.919 - 2.423 0.464 - 321.5 1 2 0 0.0031 10 0 0 0 6.26E+07 5.86E+07 - - - 4.9375 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.14382.14382.2 0.0424 18-Nov R.IATANMLGIR[166.11].K sp|Q9NX20|RM16_HUMAN 1 1068.5989 1.1 20738 14382 2 1068.601547 535.3067 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3089.2 - 535841 - - - 2.4584 - 1.827 0.254 - 385.1 1 2 0 0.0026 10 0 0 0 6.26E+07 5.67E+07 - - - 2.5985 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.14383.14383.2 0.00436 16-Aug R.AYALAFAER[166.11].G "sp|P51659|DHB4_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HLJ0|A0A804HLJ0_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HKT2|A0A804HKT2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN,tr|A0A2R8YEG2|A0A2R8YEG2_HUMAN" 12 1020.5268 2.27 20739 14383 2 1020.52946 511.2707 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6.05 3089.4 - 513474 - - - 2.6055 - 1.722 0.417 - 237.4 1 2 0 0.0027 9 0 0 0 3.07E+07 1.35E+07 - - - 3.6925 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.14385.14385.2 0.00446 22-Sep K.SPILVATAVAAR[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1177.7058 1.11 20740 14385 2 1177.709245 589.8602 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3089.6 - 212108 - - - 2.9014 - 2.049 0.187 - 185.5 1 2 0 0.0034 12 0 0 0 7.04E+08 6.35E+08 - - - 2.3086 0.999 230117_WJC_METTL3_WT_vs_EV_F03.14388.14388.2 0.0172 14-Aug K.LITEDFVR.Q sp|Q96MG7|NSE3_HUMAN 1 991.5338 5.84 20742 14388 2 991.536407 496.7742 Non-structural maintenance of chromosomes element 3 homolog OS=Homo sapiens OX=9606 GN=NSMCE3 PE=1 SV=1 4.37 3089.9 - 548847 - - - 2.5829 - 1.669 0.3 - 184.8 1 2 0 0.0026 8 0 0 0 1.93E+07 3.30E+06 - - - 2.8008 0.9021 230117_WJC_METTL3_WT_vs_EV_F03.14394.14394.2 9 12-May K.RIYGGFK[136.11].S sp|Q14520|HABP2_HUMAN 1 847.4796 - 20746 14394 2 847.481331 424.7471 Hyaluronan-binding protein 2 OS=Homo sapiens OX=9606 GN=HABP2 PE=1 SV=1 9.99 3090.8 - 1.45E+06 - - - 2.0744 - 1.078 0.019 - 45.5 7 2 0 0.0018 7 0 0 0 - - - - - -0.9587 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.14398.14398.2 0.000433 18-Jul K.LFPGSPAIYK.L "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|F8W705|F8W705_HUMAN,tr|C9JF75|C9JF75_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|C9J6W1|C9J6W1_HUMAN,tr|H0YBN8|H0YBN8_HUMAN,tr|C9J1W9|C9J1W9_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 17 1091.6015 1.8 20749 14398 2 1091.604793 546.808 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 8.59 3091.2 - 498932 - - - 2.9874 - 1.424 0.374 - 136.7 1 2 0 0.0033 10 0 0 0 5.11E+07 2.84E+07 - - - 2.789 0.996 230117_WJC_METTL3_WT_vs_EV_F03.14402.14402.2 0.0641 12-Jul R.FLTFAER[166.11].L sp|O75691|UTP20_HUMAN 1 892.4682 0.98 20752 14402 2 892.469822 447.2414 Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3 6 3091.6 - 909780 - - - 1.7917 - 1.252 0.195 - 171.1 1 2 0 0.0016 7 0 0 0 1.96E+07 1.99E+07 - - - 1.1929 0.9724 230117_WJC_METTL3_WT_vs_EV_F03.14408.14408.2 1.42 16-Oct R.AGVIFPVGR[166.11].L "sp|Q9P0M6|H2AW_HUMAN,sp|O75367|H2AY_HUMAN,tr|A0A7I2YQD6|A0A7I2YQD6_HUMAN,tr|B4DJC3|B4DJC3_HUMAN,tr|A0A7I2V412|A0A7I2V412_HUMAN,tr|Q5SQT3|Q5SQT3_HUMAN,tr|A0A7I2V423|A0A7I2V423_HUMAN,tr|A0A7I2V2N7|A0A7I2V2N7_HUMAN,tr|A0A7I2V4D9|A0A7I2V4D9_HUMAN,tr|D6RCF2|D6RCF2_HUMAN,tr|A0A7I2V6E9|A0A7I2V6E9_HUMAN,tr|A0A7I2YQB9|A0A7I2YQB9_HUMAN,tr|A0A7I2YQR8|A0A7I2YQR8_HUMAN" 13 924.5421 0.74 20756 14408 2 924.545372 463.2783 Core histone macro-H2A.2 OS=Homo sapiens OX=9606 GN=MACROH2A2 PE=1 SV=3 9.79 3092.4 - 1.12E+06 - - - 3.5856 - 1.538 0.02 - 371.7 1 2 0 0.0033 9 0 0 0 7.31E+07 9.85E+07 - - - 0.4331 0.999 230117_WJC_METTL3_WT_vs_EV_F03.14413.14413.2 0.0221 14-Aug K.VPGIFISR.M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 887.5229 0.48 20759 14413 2 887.523682 444.7687 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3093 - 2.41E+06 - - - 0.8946 - 1.518 0.307 - 196.9 2 2 0 0.0008 8 0 0 0 1.16E+08 2.42E+08 - - - 2.4326 0.999 230117_WJC_METTL3_WT_vs_EV_F03.14415.14415.2 0.00282 16-Sep K.TLAIELAPR[166.11].N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 992.5894 1.3 20761 14415 2 992.59251 497.302 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3093.2 - 857671 - - - 3.1322 - 1.732 0.352 - 275 1 2 0 0.0031 9 0 0 0 2.05E+09 1.58E+09 - - - 3.229 0.9214 230117_WJC_METTL3_WT_vs_EV_F03.14416.14416.2 0.397 14-Jul K.ATALPLLK.Q sp|Q9Y2P8|RCL1_HUMAN 1 825.5324 0.77 20762 14416 2 825.536398 413.7735 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 8.8 3093.3 - 649703 - - - 4.855 - 1.463 0.041 - 89.1 3 2 0 0.004 8 0 0 0 4.52E+07 5.84E+07 - - - 0.277 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.14418.14418.2 0.00789 22-Aug K.SPILVATAVAAR.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1167.6976 1.11 20763 14418 2 1167.70083 584.8561 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3093.5 - 56516 - - - 2.8021 - 1.849 0.131 - 98.3 1 2 0 0.0033 12 0 0 0 7.03E+08 6.33E+08 - - - 1.6248 1 230117_WJC_METTL3_WT_vs_EV_F03.14420.14420.2 3.66E-05 16-Oct K.MYLQAAIVR.L "sp|Q13617|CUL2_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 2 1063.5848 3 20764 14420 2 1063.585785 532.7997 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 8.5 3093.8 - 1.01E+06 - - - 0.8923 - 1.879 0.544 - 433.5 1 2 0 0.0009 9 0 0 0 2.32E+07 7.72E+06 - - - 4.8834 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.14423.14423.2 0.00418 20-Jul K.LIPGPLSPVAR[166.11].G sp|P48634|PRC2A_HUMAN 1 1128.6894 1.23 20767 14423 2 1128.69114 565.352 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3094.1 - 253360 - - - 1.4982 - 1.549 0.341 - 145.6 1 2 0 0.0017 11 0 0 0 5.78E+08 4.68E+08 - - - 2.7429 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.14424.14424.2 0.0109 20-Sep M.VPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1175.7278 2.73 20768 14424 2 1175.729859 588.8712 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.72 3094.3 - 194733 - - - 1.7555 - 1.719 0.285 - 133.9 1 2 0 0.0021 11 0 0 0 1.65E+07 6.02E+06 - - - 2.6109 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.14428.14428.2 0.551 14-Sep K.VPGIFISR[166.11].M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 897.5312 0.2 20770 14428 2 897.533058 449.7729 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3094.7 - 1.99E+06 - - - 2.1169 - 1.61 0.114 - 322.3 1 2 0 0.0019 8 0 0 0 1.16E+08 5.78E+08 - - - 1.3187 0.9939 230117_WJC_METTL3_WT_vs_EV_F03.14429.14429.2 0.419 16-Jul R.VLQALEGLK[136.11].M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 977.6001 1.41 20771 14429 2 977.605023 489.8073 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3094.8 - 1.31E+06 - - - 5.0542 - 1.611 0.29 - 105.4 1 2 0 0.0049 9 0 0 0 9.28E+08 6.57E+08 - - - 2.561 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.14430.14430.2 0.014 16-Aug R.FLAEEGFYK[136.11].F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1110.5477 1.22 20772 14430 2 1110.547483 556.2811 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3094.9 - 292102 - - - -0.2062 - 1.571 0.395 - 140 1 2 0 -0.0002 9 0 0 0 1.32E+08 1.08E+08 - - - 3.2652 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.14433.14433.2 0.521 12-Aug K.LPNLLGR[166.11].A sp|Q9Y512|SAM50_HUMAN 1 791.4893 1.16 20773 14433 2 791.490573 396.7519 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 9.75 3095.5 - 852970 - - - 1.6172 - 1.411 0.184 - 137.4 1 2 0 0.0013 7 0 0 0 3.26E+07 2.80E+07 - - - 1.4906 0.9885 230117_WJC_METTL3_WT_vs_EV_F03.14438.14438.2 10.2 12-Aug K.IGIEIIK.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 784.5058 2.07 20777 14438 2 784.506432 393.2602 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3096 - 1.11E+06 - - - 0.7533 - 1.613 0.001 - 139.9 2 2 0 0.0006 7 0 0 0 1.68E+10 8.11E+09 - - - 0.4286 0.998 230117_WJC_METTL3_WT_vs_EV_F03.14439.14439.2 0.105 12-Aug R.IAAYLFK.G "sp|Q00610|CLH1_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|J3KRF5|J3KRF5_HUMAN" 5 824.4796 1.06 20778 14439 2 824.481281 413.2471 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.59 3096.1 - 580655 - - - 2.0073 - 1.665 0.16 - 154.8 1 2 0 0.0017 7 0 0 0 3.76E+08 3.56E+08 - - - 1.8376 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.14441.14441.2 0.000956 18-Sep K.WTLLQEQGTK.T "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1202.6295 999 20780 14441 2 1202.631838 602.322 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6 3096.3 - 181747 - - - 1.9125 - 1.656 0.085 - 223.7 1 2 0 0.0023 10 0 0 0 2.77E+06 0.00E+00 - - - 1.076 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.14444.14444.2 1.97E-05 16-Sep R.FLAEEGFYK.F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1102.5335 1.22 20781 14444 2 1102.535705 552.274 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3096.7 - 771240 - - - 1.9891 - 1.679 0.54 - 210.9 1 2 0 0.0022 9 0 0 0 1.32E+08 1.08E+08 - - - 4.5279 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.14447.14447.2 0.772 14-Aug R.IGFIEEVK.A sp|Q96P63|SPB12_HUMAN 1 933.5171 28.09 20784 14447 2 933.518832 467.7658 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 4.53 3096.9 - 5.19E+06 - - - 1.8189 - 1.653 0.147 - 147.4 1 2 0 0.0017 8 0 0 0 2.02E+08 7.19E+06 - - - 1.642 0.8867 230117_WJC_METTL3_WT_vs_EV_F03.14452.14452.2 6.22 12-Jun K.MLPTFVR.A "sp|Q2TB90|HKDC1_HUMAN,sp|P52790|HXK3_HUMAN,sp|P19367|HXK1_HUMAN,sp|P52789|HXK2_HUMAN,tr|E9PB90|E9PB90_HUMAN,tr|B1AR62|B1AR62_HUMAN" 6 862.4735 1.16 20787 14452 2 862.471517 432.244 Hexokinase HKDC1 OS=Homo sapiens OX=9606 GN=HKDC1 PE=1 SV=3 9.5 3097.6 - 585286 - - - -2.2934 - 1.081 0.096 - 148.7 1 2 0 -0.002 7 0 0 0 6.12E+07 5.30E+07 - - - -0.0038 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.14460.14460.2 1.63E-05 20-Oct K.LIPGPLSPVAR.G sp|P48634|PRC2A_HUMAN 1 1118.6812 1.23 20792 14460 2 1118.683554 560.3479 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3098.5 - 2.33E+06 - - - 2.123 - 1.718 0.544 - 437.6 1 2 0 0.0024 11 0 0 0 5.78E+08 4.68E+08 - - - 4.5222 0.9835 230117_WJC_METTL3_WT_vs_EV_F03.14466.14466.2 1.62 14-Jul K.LITDDFVK.Q sp|Q96JG8|MAGD4_HUMAN 1 949.512 4.57 20796 14466 2 949.512935 475.7633 Melanoma-associated antigen D4 OS=Homo sapiens OX=9606 GN=MAGED4 PE=1 SV=3 4.21 3099.2 - 1.50E+06 - - - 0.9342 - 1.126 0.102 - 107.7 1 2 0 0.0009 8 0 0 0 1.25E+07 2.73E+06 - - - 0.152 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.14472.14472.2 0.25 20-Jul K.ILATTPSAVFR.V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1174.671 1.92 20800 14472 2 1174.671583 588.3428 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3099.8 - 332103 - - - 0.4886 - 1.351 0.236 - 106.7 1 2 0 0.0006 11 0 0 0 6.84E+07 3.57E+07 - - - 1.5978 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.14482.14482.2 0.207 20-Jul K.ILATTPSAVFR[166.11].V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1184.6793 1.92 20806 14482 2 1184.679951 593.3469 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3101.1 - 198303 - - - 0.5672 - 1.388 0.286 - 113.4 1 2 0 0.0007 11 0 0 0 6.84E+07 3.57E+07 - - - 2.0401 0.9961 230117_WJC_METTL3_WT_vs_EV_F03.14485.14485.2 0.258 14-Aug R.ELVITIAR[166.11].E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 923.5679 1.24 20807 14485 2 923.568072 462.7912 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3101.5 - 2.70E+06 - - - 0.1462 - 1.357 0.197 - 256.7 1 2 0 0.0001 8 0 0 0 2.89E+08 2.34E+08 - - - 1.4167 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.14488.14488.2 0.0547 16-Aug R.VLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 969.5859 1.41 20809 14488 2 969.586506 485.8002 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3101.9 - 2.74E+07 - - - 0.6436 - 1.819 0.27 - 248.7 1 2 0 0.0006 9 0 0 0 9.27E+08 6.57E+08 - - - 2.7659 0.997 230117_WJC_METTL3_WT_vs_EV_F03.14491.14491.2 0.113 14-Aug R.IGFIEEVK.A sp|Q96P63|SPB12_HUMAN 1 933.5171 28.09 20811 14491 2 933.517461 467.7658 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 4.53 3102.1 - 3.29E+06 - - - 0.3503 - 1.418 0.197 - 144.2 1 2 0 0.0003 8 0 0 0 2.02E+08 7.19E+06 - - - 1.5493 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.14497.14497.2 0.00735 14-Sep K.QFFVAVER[166.11].E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1004.5319 0.87 20814 14497 2 1004.530938 503.2732 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 6 3103 - 1.18E+06 - - - -0.9437 - 1.558 0.277 - 272.8 1 2 0 -0.0009 8 0 0 0 7.15E+07 8.21E+07 - - - 2.4239 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.14507.14507.2 0.22 14-Aug R.ELVITIAR.E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 913.5597 1.24 20820 14507 2 913.559428 457.7871 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3104.2 - 9.54E+06 - - - -0.2616 - 1.514 0.221 - 384.6 1 2 0 -0.0002 8 0 0 0 2.90E+08 2.34E+08 - - - 1.9241 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.14508.14508.2 0.0674 12-Jun R.FWETLDR.Y "sp|Q6P1J9|CDC73_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN" 2 965.4607 1.74 20821 14508 2 965.460057 483.7376 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 4.37 3104.3 - 746034 - - - -0.6463 - 1.409 0.337 - 113.3 1 2 0 -0.0006 7 0 0 0 5.46E+07 3.15E+07 - - - 2.6163 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.14509.14509.2 0.141 18-Oct K.AIITALGVER.R sp|Q92616|GCN1_HUMAN 1 1041.6182 1.82 20822 14509 2 1041.618344 521.8164 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 6.05 3104.4 - 2.51E+06 - - - 0.095 - 2.261 0.285 - 360.8 1 2 0 0.0001 10 0 0 0 7.66E+07 4.20E+07 - - - 3.4231 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.14526.14526.2 0.000743 18-Sep K.IMLVEPPVAK.V sp|P18583|SON_HUMAN 1 1095.6362 1.71 20830 14526 2 1095.636709 548.8254 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3106.6 - 1.41E+06 - - - 0.4618 - 1.881 0.373 - 213.9 1 2 0 0.0005 10 0 0 0 7.04E+07 4.12E+07 - - - 3.5594 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.14534.14534.2 0.000286 16-Sep R.GSPLLIGVR.S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 910.56 1.6 20835 14534 2 910.560177 456.2873 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3107.5 - 2.67E+06 - - - 0.1922 - 1.842 0.487 - 344.1 1 2 0 0.0002 9 0 0 0 2.38E+08 1.49E+08 - - - 4.4052 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.14543.14543.2 0.00733 16-Nov R.GSPLLIGVR[166.11].S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 920.5683 1.6 20839 14543 2 920.568499 461.2914 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3108.7 - 1.83E+06 - - - 0.2466 - 1.977 0.422 - 553.4 1 2 0 0.0002 9 0 0 0 2.38E+08 1.49E+08 - - - 4.1297 0.9745 230117_WJC_METTL3_WT_vs_EV_F03.14544.14544.2 3.75 12-Jun R.IFFVSAK.E "sp|O95140|MFN2_HUMAN,sp|Q8IWA4|MFN1_HUMAN,tr|A0A6Q8PGV8|A0A6Q8PGV8_HUMAN,tr|H7C5H5|H7C5H5_HUMAN,tr|A0A6Q8PFJ4|A0A6Q8PFJ4_HUMAN,tr|A0A6Q8PGA3|A0A6Q8PGA3_HUMAN,tr|A0A6Q8PGS9|A0A6Q8PGS9_HUMAN" 7 810.464 0.58 20840 14544 2 810.463279 406.2393 Mitofusin-2 OS=Homo sapiens OX=9606 GN=MFN2 PE=1 SV=3 8.75 3108.7 - 349151 - - - -0.86 - 1.113 0.144 - 82 1 2 0 -0.0007 7 0 0 0 1.94E+07 3.32E+07 - - - 0.4436 0.999 230117_WJC_METTL3_WT_vs_EV_F03.14549.14549.2 0.00152 16-Jul R.VYSYALALK.H "sp|Q9UKK9|NUDT5_HUMAN,tr|A6NFX8|A6NFX8_HUMAN" 2 1026.575 3.97 20843 14549 2 1026.575107 514.2948 ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1 8.47 3109.4 - 1.40E+06 - - - 0.1208 - 1.38 0.37 - 121.8 1 2 0 0.0001 9 0 0 0 4.76E+07 1.20E+07 - - - 2.7056 0.9925 230117_WJC_METTL3_WT_vs_EV_F03.14559.14559.2 0.691 12-Jul R.TLDTFLR[166.11].S sp|Q96SK2|TM209_HUMAN 1 874.4788 1.67 20848 14559 2 874.479291 438.2467 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 5.5 3110.7 - 1.22E+06 - - - 0.5752 - 1.212 0.152 - 181.7 1 2 0 0.0005 7 0 0 0 5.95E+07 3.57E+07 - - - 0.7727 0.9511 230117_WJC_METTL3_WT_vs_EV_F03.14568.14568.2 3.25 14-Jul K.LITDEFVK[136.11].Q "sp|Q12816|TROP_HUMAN,sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN,tr|A0A087X070|A0A087X070_HUMAN,tr|G5E9N2|G5E9N2_HUMAN" 6 971.5419 1.18 20854 14568 2 971.540544 486.7782 Trophinin OS=Homo sapiens OX=9606 GN=TRO PE=1 SV=3 4.37 3111.7 - 1.51E+06 - - - -1.3937 - 1.109 0.117 - 91.9 1 2 0 -0.0014 8 0 0 0 4.00E+08 3.40E+08 - - - 0.2168 0.9948 230117_WJC_METTL3_WT_vs_EV_F03.14572.14572.2 0.247 12-Aug R.TLDTFLR.S sp|Q96SK2|TM209_HUMAN 1 864.4705 1.67 20856 14572 2 864.470013 433.2425 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 5.5 3112.2 - 2.18E+06 - - - -0.5842 - 1.376 0.2 - 175.9 1 2 0 -0.0005 7 0 0 0 6.05E+07 3.62E+07 - - - 1.5294 0.9961 230117_WJC_METTL3_WT_vs_EV_F03.14573.14573.2 0.0605 14-Aug K.LITDEFVK.Q "sp|Q12816|TROP_HUMAN,sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN,tr|A0A087X070|A0A087X070_HUMAN,tr|G5E9N2|G5E9N2_HUMAN" 6 963.5277 1.18 20857 14573 2 963.528712 482.7711 Trophinin OS=Homo sapiens OX=9606 GN=TRO PE=1 SV=3 4.37 3112.3 - 2.91E+06 - - - 1.0524 - 1.264 0.193 - 151.4 1 2 0 0.001 8 0 0 0 4.00E+08 3.40E+08 - - - 1.1728 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.14576.14576.2 0.246 16-Aug K.EGLVMVEVR[166.11].K sp|Q7KZF4|SND1_HUMAN 1 1040.5564 80.82 20860 14576 2 1040.557577 521.2855 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.53 3112.7 - 247676 - - - 1.1446 - 1.557 0.23 - 140.3 1 2 0 0.0012 9 0 0 0 7.04E+08 8.71E+06 - - - 2.0203 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.14580.14580.2 0.0157 16-Sep K.FVGNIYTLK[136.11].C "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1061.6001 2.08 20862 14580 2 1061.600428 531.8073 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3113.2 - 1.05E+06 - - - 0.3259 - 1.587 0.352 - 188.9 1 2 0 0.0003 9 0 0 0 1.33E+08 6.36E+07 - - - 2.9769 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.14586.14586.2 0.00215 16-Sep R.MGPNIYELR.T "sp|Q9BPW8|NIPS1_HUMAN,tr|C9JDV8|C9JDV8_HUMAN,tr|H7C2U6|H7C2U6_HUMAN" 3 1091.5434 1.59 20866 14586 2 1091.543068 546.779 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.75 3113.9 - 140946 - - - -0.2721 - 1.864 0.389 - 268.8 1 2 0 -0.0003 9 0 0 0 6.89E+07 4.33E+07 - - - 3.7156 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.14590.14590.2 0.00456 16-Aug R.MGPNIYELR[166.11].T "sp|Q9BPW8|NIPS1_HUMAN,tr|C9JDV8|C9JDV8_HUMAN,tr|H7C2U6|H7C2U6_HUMAN" 3 1101.5516 1.59 20868 14590 2 1101.553191 551.7831 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.75 3114.5 - 715828 - - - 1.4126 - 1.75 0.381 - 184.7 1 2 0 0.0016 9 0 0 0 6.87E+07 4.33E+07 - - - 3.4736 0.9752 230117_WJC_METTL3_WT_vs_EV_F03.14591.14591.2 0.181 12-Aug R.LMDLLQK[136.11].K sp|Q9UJV9|DDX41_HUMAN 1 867.4979 0.94 20869 14591 2 867.497759 434.7562 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.84 3114.5 - 3.69E+06 - - - -0.1914 - 1.43 0.001 - 174.5 1 2 0 -0.0002 7 0 0 0 7.31E+07 7.75E+07 - - - 0.1816 0.9962 230117_WJC_METTL3_WT_vs_EV_F03.14592.14592.2 0.281 16-Jul K.LVTEPLVLK[136.11].S sp|O43896|KIF1C_HUMAN 1 1018.6518 1.02 20870 14592 2 1018.655535 510.3332 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 6 3114.7 - 1.65E+06 - - - 3.6833 - 1.508 0.252 - 131.1 1 2 0 0.0038 9 0 0 0 4.07E+07 3.99E+07 - - - 2.0895 0.9955 230117_WJC_METTL3_WT_vs_EV_F03.14596.14596.2 0.101 14-Jun R.EFADFEYR[166.11].K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1085.4693 1.24 20872 14596 2 1085.467477 543.7419 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3115.1 - 195131 - - - -1.7209 - 1.342 0.326 - 131.4 1 2 0 -0.0019 8 0 0 0 2.04E+07 1.65E+07 - - - 2.3354 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.14597.14597.2 0.00542 14-Jun R.EFADFEYR.K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1075.4611 1.24 20873 14597 2 1075.463001 538.7378 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3115.2 - 148155 - - - 1.7909 - 1.334 0.401 - 149 1 2 0 0.0019 8 0 0 0 2.04E+07 1.65E+07 - - - 2.8713 0.9935 230117_WJC_METTL3_WT_vs_EV_F03.14602.14602.2 0.982 12-May R.FPYYLSR.H sp|Q8NAF0|ZN579_HUMAN 1 944.4756 -1 20876 14602 2 944.476038 473.2451 Zinc finger protein 579 OS=Homo sapiens OX=9606 GN=ZNF579 PE=1 SV=2 8.59 3115.8 - 375836 - - - 0.4606 - 1.235 0.162 - 49.1 1 2 0 0.0004 7 0 0 0 0.00E+00 0.00E+00 - - - 0.9062 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.14618.14618.2 0.00226 16-Sep K.LVTEPLVLK.S sp|O43896|KIF1C_HUMAN 1 1010.6376 0.74 20885 14618 2 1010.638409 506.3261 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 6 3117.9 - 1.98E+06 - - - 0.8173 - 1.776 0.421 - 177.6 1 2 0 0.0008 9 0 0 0 4.11E+07 5.53E+07 - - - 3.8119 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.14632.14632.2 0.0078 18-Nov R.VVVDALSGLK[136.11].G "sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|F8WCN3|F8WCN3_HUMAN" 3 1007.6106 1.85 20891 14632 2 1007.611636 504.8126 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 5.81 3119.6 - 1.78E+06 - - - 0.9815 - 2.13 0.369 - 357 1 2 0 0.001 10 0 0 0 1.03E+08 5.54E+07 - - - 3.8767 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.14656.14656.2 0.258 14-Aug K.IIYIAPMR[166.11].S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 985.5658 1.41 20903 14656 2 985.567069 493.7902 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 3122.6 - 2.72E+06 - - - 1.2582 - 1.525 0.244 - 205.1 1 2 0 0.0012 8 0 0 0 1.33E+08 9.40E+07 - - - 2.1155 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.14657.14657.2 0.0685 14-Jun K.LLESDYFR.Y "sp|Q96HE7|ERO1A_HUMAN,tr|G3V503|G3V503_HUMAN,tr|G3V3E6|G3V3E6_HUMAN" 3 1041.5131 1.91 20904 14657 2 1041.512654 521.7638 ERO1-like protein alpha OS=Homo sapiens OX=9606 GN=ERO1A PE=1 SV=2 4.37 3122.7 - 421465 - - - -0.4388 - 1.243 0.396 - 97.9 1 2 0 -0.0005 8 0 0 0 1.33E+07 6.96E+06 - - - 2.6218 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.14658.14658.2 1.04 16-Jul K.LGIIGVVNR.S "sp|O00429|DNM1L_HUMAN,tr|F8VZ52|F8VZ52_HUMAN" 2 939.5866 1.44 20905 14658 2 939.587577 470.8006 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 9.75 3122.8 - 2.38E+06 - - - 1.092 - 1.656 0.245 - 107 3 2 0 0.001 9 0 0 0 8.17E+07 5.68E+07 - - - 2.0964 0.8982 230117_WJC_METTL3_WT_vs_EV_F03.14668.14668.2 2.74 14-Jun K.IPGLVTLK[136.11].K "sp|Q9UK61|TASOR_HUMAN,tr|A0A087X0F1|A0A087X0F1_HUMAN" 2 847.5622 1.63 20912 14668 2 847.562308 424.7884 Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3 8.75 3123.8 - 590520 - - - 0.0802 - 1.036 0.018 - 65.8 2 2 0 0.0001 8 0 0 0 2.63E+07 1.61E+07 - - - -0.8539 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.14674.14674.2 0.00189 12-Sep R.TMLLLSR.S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 832.4841 1.93 20914 14674 2 832.485059 417.2493 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.41 3124.7 - 5.00E+06 - - - 1.2012 - 1.717 0.252 - 437.6 1 2 0 0.001 7 0 0 0 1.17E+08 6.04E+07 - - - 2.6148 0.9906 230117_WJC_METTL3_WT_vs_EV_F03.14678.14678.2 0.72 16-May R.VIMSDLQIR[166.11].G "sp|Q9UIF9|BAZ2A_HUMAN,tr|A0A0C4DGI9|A0A0C4DGI9_HUMAN,tr|F8VU39|F8VU39_HUMAN,tr|J3KPG5|J3KPG5_HUMAN" 4 1083.5986 1.03 20918 14678 2 1083.598334 542.8066 Bromodomain adjacent to zinc finger domain protein 2A OS=Homo sapiens OX=9606 GN=BAZ2A PE=1 SV=4 5.81 3125.1 - 148043 - - - -0.2316 - 1.082 0.219 - 61 1 2 0 -0.0003 9 0 0 0 2.84E+06 2.75E+06 - - - 0.8865 0.9969 230117_WJC_METTL3_WT_vs_EV_F03.14682.14682.2 0.101 14-Jun K.LTPLLSVR.E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 897.5648 0.91 20920 14682 2 897.565411 449.7897 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3125.6 - 1.07E+06 - - - 0.7331 - 1.322 0.209 - 126 1 2 0 0.0007 8 0 0 0 2.27E+08 2.49E+08 - - - 1.4264 0.9916 230117_WJC_METTL3_WT_vs_EV_F03.14686.14686.2 0.477 18-Sep R.AGLTEPVLIR[166.11].L sp|Q8TDD1|DDX54_HUMAN 1 1077.6422 0.44 20924 14686 2 1077.641919 539.8284 ATP-dependent RNA helicase DDX54 OS=Homo sapiens OX=9606 GN=DDX54 PE=1 SV=2 6.05 3126 - 267475 - - - -0.2283 - 1.415 0.13 - 168.9 1 2 0 -0.0002 10 0 0 0 1.02E+07 2.33E+07 - - - 0.97 0.9926 230117_WJC_METTL3_WT_vs_EV_F03.14688.14688.2 15 12-Aug K.IGIEIIK.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 784.5058 2.33 20925 14688 2 784.506595 393.2602 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3126.2 - 2.05E+06 - - - 0.9611 - 1.707 0.015 - 146.5 2 2 0 0.0008 7 0 0 0 3.61E+07 1.55E+07 - - - 0.7114 0.9935 230117_WJC_METTL3_WT_vs_EV_F03.14690.14690.2 0.303 14-Apr R.KPC[160.03]SDDYR.K "sp|Q2TAA8|TXIP1_HUMAN,tr|B4DXD0|B4DXD0_HUMAN,tr|H3BQ72|H3BQ72_HUMAN,tr|H3BNS9|H3BNS9_HUMAN" 4 1039.4393 999 20926 14690 2 1039.440833 520.7269 Translin-associated factor X-interacting protein 1 OS=Homo sapiens OX=9606 GN=TSNAXIP1 PE=1 SV=1 5.95 3126.4 - 186497 - - - 1.4806 - 0.929 0.265 - 38.1 1 2 0 0.0015 8 0 0 0 5.64E+06 0.00E+00 - - - 0.7757 0.993 230117_WJC_METTL3_WT_vs_EV_F03.14694.14694.2 0.343 12-Jul R.TMLLLSR[166.11].S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 842.4923 1.94 20928 14694 2 842.493585 422.2534 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.41 3126.8 - 1.31E+06 - - - 1.4908 - 1.332 0.106 - 163.2 1 2 0 0.0013 7 0 0 0 1.14E+08 5.88E+07 - - - 0.7319 0.9366 230117_WJC_METTL3_WT_vs_EV_F03.14697.14697.2 5.27 12-May K.LVLILNK.S "sp|Q9BVP2|GNL3_HUMAN,sp|Q96RW7|HMCN1_HUMAN" 2 811.5531 0.95 20931 14697 2 811.554478 406.7838 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.75 3127 - 1.41E+06 - - - 1.6672 - 1.117 0.001 - 75.2 2 2 0 0.0014 7 0 0 0 6.60E+07 6.94E+07 - - - -0.7359 0.9752 230117_WJC_METTL3_WT_vs_EV_F03.14700.14700.2 2.25 18-May R.LLENMTEVVR.K "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 1202.6329 99.22 20934 14700 2 1202.635178 602.3237 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 3127.4 - 154867 - - - 1.8867 - 1.157 0.062 - 58 1 2 0 0.0023 10 0 0 0 5.06E+06 5.10E+04 - - - -0.0947 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.14703.14703.2 0.0453 12-Sep K.FDLMYAK.R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 886.4259 3.19 20935 14703 2 886.427501 444.2202 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3127.8 - 2.02E+06 - - - 1.8332 - 1.571 0.326 - 248.4 1 2 0 0.0016 7 0 0 0 8.82E+08 2.77E+08 - - - 2.8796 0.9618 230117_WJC_METTL3_WT_vs_EV_F03.14712.14712.2 2.4 14-Jun K.LTPLLSVR[166.11].E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 907.573 0.91 20942 14712 2 907.574802 454.7938 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3128.9 - 5.18E+06 - - - 1.9602 - 1.178 0.032 - 159.9 2 2 0 0.0018 8 0 0 0 2.27E+08 2.49E+08 - - - -0.3636 0.9969 230117_WJC_METTL3_WT_vs_EV_F03.14715.14715.2 0.737 12-Aug R.VAFVNFR[166.11].R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 861.4736 1.05 20945 14715 2 861.475501 431.7441 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 9.72 3129.1 - 1.85E+06 - - - 2.1568 - 1.693 0.105 - 270.7 1 2 0 0.0019 7 0 0 0 1.17E+08 1.12E+08 - - - 1.4842 0.9887 230117_WJC_METTL3_WT_vs_EV_F03.14734.14734.2 18.5 12-Jul K.IGIEIIK[136.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 792.52 2.18 20957 14734 2 792.520346 397.2673 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3131.4 - 848680 - - - 0.3848 - 1.511 0.024 - 83.4 1 2 0 0.0003 7 0 0 0 1.77E+10 8.13E+09 - - - 0.5261 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.14735.14735.2 0.175 12-Aug R.FC[160.03]DVLLR.V "sp|Q9HBE1|PATZ1_HUMAN,tr|B1ARF3|B1ARF3_HUMAN" 2 921.4742 0.06 20958 14735 2 921.475593 461.7444 "POZ-, AT hook-, and zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=PATZ1 PE=1 SV=1" 5.83 3131.5 - 616277 - - - 1.4867 - 1.423 0.247 - 241.8 1 2 0 0.0014 7 0 0 0 1.96E+07 3.22E+08 - - - 1.9827 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.14737.14737.2 0.204 16-Aug K.GFVTADMIR.E sp|Q9UHQ9|NB5R1_HUMAN 1 1008.5063 1.29 20960 14737 2 1008.508363 505.2604 NADH-cytochrome b5 reductase 1 OS=Homo sapiens OX=9606 GN=CYB5R1 PE=1 SV=1 5.84 3131.7 - 451243 - - - 2.0942 - 1.537 0.291 - 205.4 1 2 0 0.0021 9 0 0 0 2.11E+07 1.64E+07 - - - 2.4332 0.8761 230117_WJC_METTL3_WT_vs_EV_F03.14746.14746.2 1.43 12-Jun K.LFQPFGK[136.11].V sp|Q14966|ZN638_HUMAN 1 843.4734 1.2 20967 14746 2 843.473425 422.744 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 8.75 3132.8 - 482149 - - - 0 - 1.01 0.024 - 86.1 3 2 0 0 7 0 0 0 5.05E+07 4.22E+07 - - - -0.9633 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.14750.14750.2 0.000437 12-Jul K.FDLMYAK[136.11].R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 894.4401 3.19 20969 14750 2 894.44088 448.2273 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3133.3 - 8.69E+06 - - - 0.8989 - 1.621 0.305 - 142.2 1 2 0 0.0008 7 0 0 0 8.82E+08 2.77E+08 - - - 2.824 0.9881 230117_WJC_METTL3_WT_vs_EV_F03.14752.14752.2 2.26 12-Jul R.AVTIFIR.G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 818.5014 4.29 20971 14752 2 818.50242 410.258 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3133.5 - 7.08E+06 - - - 1.2169 - 1.366 0.044 - 231.3 1 2 0 0.001 7 0 0 0 2.35E+09 5.47E+08 - - - 0.3539 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.14753.14753.2 0.218 18-Oct R.VLLGEGVLTK[136.11].E "sp|Q96S99|PKHF1_HUMAN,sp|Q9H8W4|PKHF2_HUMAN,tr|K7ELB8|K7ELB8_HUMAN,tr|K7EIX0|K7EIX0_HUMAN" 4 1035.6419 0.73 20972 14753 2 1035.642439 518.8282 Pleckstrin homology domain-containing family F member 1 OS=Homo sapiens OX=9606 GN=PLEKHF1 PE=1 SV=3 5.97 3133.5 - 2.76E+06 - - - 0.4751 - 1.95 0.395 - 253.8 1 2 0 0.0005 10 0 0 0 3.23E+07 4.44E+07 - - - 3.8224 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.14758.14758.2 0.769 18-Jul K.IPVPINAELR[166.11].K "sp|O14981|BTAF1_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 2 1130.6687 2.32 20975 14758 2 1130.669695 566.3416 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 6 3134.2 - 161271 - - - 0.8676 - 1.53 0.248 - 98.1 2 2 0 0.001 10 0 0 0 4.79E+06 2.07E+06 - - - 1.925 0.9575 230117_WJC_METTL3_WT_vs_EV_F03.14765.14765.2 1.58 14-Aug R.LYELDGLR[166.11].E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 987.5265 2.78 20980 14765 2 987.523957 494.7705 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3135 - 805815 - - - -2.5407 - 1.473 0.113 - 169.1 3 2 0 -0.0025 8 0 0 0 5.70E+08 2.05E+08 - - - 0.8298 0.9873 230117_WJC_METTL3_WT_vs_EV_F03.14771.14771.2 0.33 16-May K.LISYSYMVR[166.11].G sp|P07099|HYEP_HUMAN 1 1140.5877 1.14 20985 14771 2 1140.587491 571.3011 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 8.59 3135.8 - 234974 - - - -0.171 - 1.048 0.198 - 52 1 2 0 -0.0002 9 0 0 0 1.94E+07 1.70E+07 - - - 0.639 0.9955 230117_WJC_METTL3_WT_vs_EV_F03.14774.14774.2 0.71 14-Jul R.LYELDGLR.E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 977.5182 2.76 20986 14774 2 977.520522 489.7664 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3136.2 - 2.86E+06 - - - 2.3795 - 1.414 0.158 - 174.9 1 2 0 0.0023 8 0 0 0 5.65E+08 2.05E+08 - - - 1.2521 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.14778.14778.2 0.0374 12-Jun R.ELFVMAR.E "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QSA9|J3QSA9_HUMAN" 4 864.4528 4.72 20988 14778 2 864.452313 433.2337 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 6.1 3136.6 - 2.30E+06 - - - -0.5159 - 1.388 0.272 - 178.5 1 2 0 -0.0004 7 0 0 0 1.78E+08 3.77E+07 - - - 2.0887 0.9677 230117_WJC_METTL3_WT_vs_EV_F03.14792.14792.2 0.414 12-Aug R.VAFVNFR.R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 851.4654 1.02 20996 14792 2 851.464442 426.74 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 9.72 3138.2 - 877776 - - - -1.0934 - 1.299 0.069 - 226.2 1 2 0 -0.0009 7 0 0 0 1.14E+08 1.12E+08 - - - 0.3792 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.14793.14793.2 0.00429 16-Sep K.IPFASLASR.L sp|P35573|GDE_HUMAN 1 960.5393 0.32 20997 14793 2 960.540467 481.2769 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3138.3 - 457242 - - - 1.2503 - 1.758 0.36 - 264.1 1 2 0 0.0012 9 0 0 0 2.91E+07 9.06E+07 - - - 3.3318 0.8827 230117_WJC_METTL3_WT_vs_EV_F03.14820.14820.2 0.00199 14-Nov R.YPDGIISK.P sp|Q86U44|MTA70_HUMAN 1 891.4702 11.04 21009 14820 2 891.469068 446.7424 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3142.1 - 2.66E+06 - - - -1.2507 - 1.735 0.332 - 341.2 1 1 0 -0.0011 8 0 0 0 2.01E+08 1.82E+07 - - - 3.1546 0.9406 230117_WJC_METTL3_WT_vs_EV_F03.14833.14833.2 0.31 12-Jul K.YLPDIIK.D sp|O15355|PPM1G_HUMAN 1 860.5008 3.99 21012 14833 2 860.496626 431.2577 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 5.83 3144 - 3.89E+06 - - - -4.7984 - 1.239 0.264 - 156.7 1 2 0 -0.0041 7 0 0 0 1.99E+08 5.00E+07 - - - 1.6686 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.14834.14834.2 0.000407 13/22 K.FAQALGLTEAVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1246.6921 0.92 21013 14834 2 1246.689209 624.3533 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3144.1 - 977364 - - - -2.3494 - 2.327 0.437 - 536.6 1 2 0 -0.0029 12 0 0 0 2.63E+07 2.87E+07 - - - 4.49 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.14835.14835.2 0.0117 14-Aug R.DAFVYAIK.N "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 925.4909 0.88 21014 14835 2 925.489532 463.7527 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 5.83 3144.2 - 3.44E+06 - - - -1.4987 - 1.53 0.294 - 272.7 1 2 0 -0.0014 8 0 0 0 1.31E+08 1.50E+08 - - - 2.4946 1 230117_WJC_METTL3_WT_vs_EV_F03.14842.14842.2 1.10E-07 22-Nov K.FAQALGLTEAVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1254.7063 0.92 21017 14842 2 1254.704832 628.3604 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3145.1 - 876240 - - - -1.2003 - 2.33 0.482 - 400.8 1 2 0 -0.0015 12 0 0 0 2.63E+07 2.87E+07 - - - 4.8262 0.9475 230117_WJC_METTL3_WT_vs_EV_F03.14846.14846.2 0.052 12-Jul K.LGFEEFK.Y "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 868.4331 2.6 21019 14846 2 868.431647 435.2238 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 3145.7 - 4.00E+06 - - - -1.6386 - 1.152 0.106 - 131.4 1 2 0 -0.0014 7 0 0 0 2.29E+08 8.80E+07 - - - 0.2718 0.9615 230117_WJC_METTL3_WT_vs_EV_F03.14848.14848.2 0.0564 12-Jul K.LGFEEFK[136.11].Y "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 876.4473 2.6 21021 14848 2 876.443722 439.2309 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 3145.9 - 1.80E+06 - - - -4.0482 - 1.602 0.152 - 133.7 1 2 0 -0.0035 7 0 0 0 2.29E+08 8.80E+07 - - - 1.6557 0.9857 230117_WJC_METTL3_WT_vs_EV_F03.14853.14853.2 0.0464 12-May R.IVFQEFR[166.11].Q "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN" 2 947.5104 0.78 21025 14853 2 947.507692 474.7625 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3146.4 - 5.03E+06 - - - -2.8812 - 1.329 0.267 - 93.8 1 2 0 -0.0027 7 0 0 0 1.72E+08 2.21E+08 - - - 1.9134 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.14862.14862.2 0.207 18-Oct R.INEILSNALK.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 3 1113.6394 7.85 21029 14862 2 1113.638202 557.827 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3147.6 - 595453 - - - -1.0524 - 1.92 0.234 - 264.5 1 2 0 -0.0012 10 0 0 0 2.21E+07 2.82E+06 - - - 2.5898 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.14871.14871.2 0.106 12-Aug K.FLSVLER[166.11].Q sp|P07099|HYEP_HUMAN 1 872.4995 0.96 21033 14871 2 872.500274 437.257 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 6 3148.8 - 3.01E+06 - - - 0.8607 - 1.668 0.257 - 218.3 1 2 0 0.0008 7 0 0 0 7.92E+07 8.23E+07 - - - 2.5601 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.14876.14876.2 0.742 16-Oct R.AFSYYGPLR[166.11].T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1082.5425 0.91 21035 14876 2 1082.540795 542.2785 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3149.4 - 1.70E+06 - - - -1.5297 - 2.088 0.331 - 396.6 1 2 0 -0.0017 9 0 0 0 2.83E+08 3.12E+08 - - - 3.6151 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.14877.14877.2 0.0558 16-Sep K.LFVQDLATR.V sp|P33176|KINH_HUMAN 1 1061.5869 1.43 21036 14877 2 1061.585056 531.8007 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 5.84 3149.5 - 544142 - - - -1.7794 - 1.787 0.292 - 312.1 1 2 0 -0.0019 9 0 0 0 2.26E+07 1.58E+07 - - - 2.8766 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.14878.14878.2 0.0146 14-Aug K.LLFYATSR.A "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 969.5284 0.47 21037 14878 2 969.526049 485.7715 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 8.75 3149.7 - 1.20E+06 - - - -2.3909 - 1.598 0.359 - 211.9 1 2 0 -0.0023 8 0 0 0 5.34E+07 1.13E+08 - - - 3.1056 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.14880.14880.2 0.119 16-Aug R.ILDSAEFIK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1042.579 0.95 21039 14880 2 1042.579683 522.2968 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3149.9 - 928937 - - - 0.6436 - 1.677 0.227 - 128.4 1 2 0 0.0007 9 0 0 0 7.68E+09 8.13E+09 - - - 2.2131 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.14881.14881.2 0.000137 16-Sep R.AFSYYGPLR.T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1072.5342 0.91 21040 14881 2 1072.533068 537.2744 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3150.1 - 831711 - - - -1.0377 - 1.69 0.497 - 293.6 1 2 0 -0.0011 9 0 0 0 2.83E+08 3.12E+08 - - - 4.2296 0.9744 230117_WJC_METTL3_WT_vs_EV_F03.14887.14887.2 0.0752 12-Jun K.YVLALVK[136.11].K "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 812.5251 1.23 21043 14887 2 812.522438 407.2698 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.59 3150.9 - 1.66E+06 - - - -3.3082 - 1.201 0.271 - 114.5 1 2 0 -0.0027 7 0 0 0 5.14E+07 4.18E+07 - - - 1.6221 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.14890.14890.2 0.00183 20-Sep K.ILQLVATGAVR.D "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A1B0GTT3|A0A1B0GTT3_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQQ5|A0A0U1RQQ5_HUMAN" 6 1139.7026 1.78 21046 14890 2 1139.700544 570.8586 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 9.75 3151.2 - 1.18E+06 - - - -1.8417 - 2.041 0.41 - 255.3 1 2 0 -0.0021 11 0 0 0 8.95E+06 5.04E+06 - - - 3.9986 0.9797 230117_WJC_METTL3_WT_vs_EV_F03.14902.14902.2 0.0514 12-Jul K.YNIMLVR.L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 907.495 8.2 21050 14902 2 907.490951 454.7548 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3152.8 - 2.79E+06 - - - -4.4155 - 1.545 0.284 - 213 1 2 0 -0.004 7 0 0 0 1.86E+09 2.27E+08 - - - 2.5158 0.9032 230117_WJC_METTL3_WT_vs_EV_F03.14903.14903.2 0.0233 14-Aug R.PFTLGQLK.E "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 902.5226 0.79 21051 14903 2 902.522538 452.2686 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 9.18 3152.9 - 838394 - - - -0.0166 - 1.681 0.255 - 193.2 1 1 0 0 8 0 0 0 4.36E+07 5.53E+07 - - - 2.4909 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.14913.14913.2 0.0315 20-Nov K.LVLLGESAVGK[136.11].S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1092.6634 1.44 21055 14913 2 1092.661855 547.339 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3154.2 - 841694 - - - -1.424 - 2.029 0.28 - 317.1 1 2 0 -0.0016 11 0 0 0 1.28E+08 8.89E+07 - - - 3.0227 0.9936 230117_WJC_METTL3_WT_vs_EV_F03.14915.14915.2 0.129 12-Jun K.YNIMLVR[166.11].L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 917.5032 8.19 21056 14915 2 917.502325 459.7589 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3154.4 - 865418 - - - -0.9842 - 1.298 0.23 - 146.8 1 2 0 -0.0009 7 0 0 0 1.86E+09 2.27E+08 - - - 1.5659 0.9819 230117_WJC_METTL3_WT_vs_EV_F03.14927.14927.2 0.336 12-Aug R.LNLYELK.E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 891.5066 2.01 21059 14927 2 891.505211 446.7606 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3156.2 - 1.44E+06 - - - -1.5233 - 1.406 0.119 - 184.1 1 2 0 -0.0014 7 0 0 0 2.26E+08 1.12E+08 - - - 0.9992 0.9173 230117_WJC_METTL3_WT_vs_EV_F03.14931.14931.2 12 12-May R.VDDFLR[166.11]R.T "sp|Q96MU7|YTDC1_HUMAN,tr|J3QR07|J3QR07_HUMAN" 2 929.4958 - 21061 14931 2 929.49558 465.7552 YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3 5.93 3156.6 - 1.27E+06 - - - -0.2743 - 1.141 0.022 - 95.1 3 2 0 -0.0003 7 0 0 0 - - - - - -0.5918 0.9457 230117_WJC_METTL3_WT_vs_EV_F03.14938.14938.2 1.19 12-Jul R.LNLYELK[136.11].E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 899.5208 1.98 21065 14938 2 899.518018 450.7677 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3157.5 - 3.70E+06 - - - -3.0583 - 1.502 0.074 - 136.6 1 2 0 -0.0028 7 0 0 0 2.26E+08 1.14E+08 - - - 0.8757 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.14943.14943.2 0.00763 20-Sep K.LVLLGESAVGK.S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1084.6492 1.44 21068 14943 2 1084.647712 543.3319 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3158.2 - 2.87E+06 - - - -1.382 - 1.883 0.23 - 193.8 1 2 0 -0.0015 11 0 0 0 1.28E+08 8.89E+07 - - - 2.4514 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.14944.14944.2 0.0042 16-Aug K.YLPELMAEK[136.11].D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1100.5667 1.17 21069 14944 2 1100.5648 551.2906 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3158.3 - 1.35E+06 - - - -1.7564 - 1.516 0.33 - 203.9 1 2 0 -0.0019 9 0 0 0 1.27E+08 1.09E+08 - - - 2.6815 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.14950.14950.2 0.357 14-Jun R.VMLYPSR[166.11]I.- sp|P18077|RL35A_HUMAN 1 987.5451 0.76 21072 14950 2 987.54483 494.7798 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.72 3159.1 - 813908 - - - -0.2663 - 1.531 0.218 - 179.7 1 2 0 -0.0003 8 0 0 0 8.47E+07 1.12E+08 - - - 1.9356 0.9957 230117_WJC_METTL3_WT_vs_EV_F03.14959.14959.2 0.0416 16-Aug K.YLPELMAEK.D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1092.5525 1.17 21076 14959 2 1092.551469 547.2835 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3160.3 - 2.92E+06 - - - -0.9739 - 1.256 0.3 - 167.6 1 2 0 -0.0011 9 0 0 0 1.27E+08 1.09E+08 - - - 1.9159 0.9337 230117_WJC_METTL3_WT_vs_EV_F03.14961.14961.2 3.79 16-Jul R.LEPLYSPIR.S sp|Q9UBB9|TFP11_HUMAN 1 1086.6073 0.9 21078 14961 2 1086.606816 544.3109 Tuftelin-interacting protein 11 OS=Homo sapiens OX=9606 GN=TFIP11 PE=1 SV=1 6 3160.5 - 1.58E+06 - - - -0.4878 - 1.026 0.089 - 83.7 2 2 0 -0.0005 9 0 0 0 2.56E+07 2.84E+07 - - - -0.362 0.9837 230117_WJC_METTL3_WT_vs_EV_F03.14968.14968.2 0.0624 12-Jun K.FADFMVK.D "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 14 856.4153 1.72 21082 14968 2 856.412496 429.2149 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 5.84 3161.3 - 1.41E+06 - - - -3.287 - 1.166 0.338 - 86.5 1 2 0 -0.0028 7 0 0 0 3.96E+07 2.31E+07 - - - 2.0232 0.99 230117_WJC_METTL3_WT_vs_EV_F03.14978.14978.2 0.498 12-Aug K.LILEYVK.A "sp|Q7L5N1|CSN6_HUMAN,tr|E7EM64|E7EM64_HUMAN" 2 876.5321 2.66 21088 14978 2 876.53381 439.2733 COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1 6 3162.6 - 1.95E+06 - - - 2.0022 - 1.367 0.07 - 172.9 1 2 0 0.0018 7 0 0 0 4.23E+07 1.59E+07 - - - 0.548 0.993 230117_WJC_METTL3_WT_vs_EV_F03.14988.14988.2 0.000988 12-Sep K.FADFMVK[136.11].D "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 14 864.4295 1.69 21093 14988 2 864.426084 433.222 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 5.84 3163.9 - 1.03E+06 - - - -3.9645 - 1.426 0.46 - 150.8 1 2 0 -0.0034 7 0 0 0 3.96E+07 2.34E+07 - - - 3.5619 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.14992.14992.2 0.0336 16-Jun R.ILDSAEFIK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1034.5648 0.95 21095 14992 2 1034.564437 518.2897 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3164.4 - 2.08E+08 - - - -0.3625 - 1.4 0.343 - 70.9 1 2 0 -0.0004 9 0 0 0 7.68E+09 8.13E+09 - - - 2.5477 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.14994.14994.2 0.0736 20-Dec R.MGAGMGFGLER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1134.519 1.89 21096 14994 2 1134.518524 568.2668 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 3164.7 - 1.10E+06 - - - -0.3799 - 1.909 0.37 - 247.6 1 2 0 -0.0004 11 0 0 0 5.32E+07 2.81E+07 - - - 3.5228 0.9934 230117_WJC_METTL3_WT_vs_EV_F03.14996.14996.2 0.0662 12-Jul K.WDPVVLK[136.11].N sp|Q9BVJ6|UT14A_HUMAN 1 863.4996 1.32 21097 14996 2 863.498247 432.7571 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 5.84 3164.9 - 1.79E+06 - - - -1.6132 - 1.14 0.33 - 107 1 2 0 -0.0014 7 0 0 0 8.73E+07 6.62E+07 - - - 1.8931 0.8472 230117_WJC_METTL3_WT_vs_EV_F03.14997.14997.2 0.795 14-Aug R.PIVTVWER[166.11].E "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EQR8|K7EQR8_HUMAN" 3 1008.5632 3.03 21098 14997 2 1008.563667 505.2889 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 6.43 3165 - 1.14E+06 - - - 0.4769 - 1.572 0.183 - 260.7 1 1 0 0.0005 8 0 0 0 1.56E+08 5.15E+07 - - - 1.7567 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.15004.15004.2 0.00319 12-Aug K.WDPVVLK.N sp|Q9BVJ6|UT14A_HUMAN 1 855.4854 1.32 21103 15004 2 855.485463 428.75 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 5.84 3165.9 - 3.51E+06 - - - 0.0269 - 1.22 0.433 - 200.3 1 2 0 0 7 0 0 0 8.73E+07 6.62E+07 - - - 2.8692 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.15009.15009.2 0.0578 14-Aug R.VMLYPSRI.- sp|P18077|RL35A_HUMAN 1 977.5368 0.76 21107 15009 2 977.537357 489.7757 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.72 3166.4 - 1.69E+06 - - - 0.5463 - 1.501 0.3 - 338.8 1 2 0 0.0005 8 0 0 0 8.52E+07 1.11E+08 - - - 2.4815 0.9078 230117_WJC_METTL3_WT_vs_EV_F03.15016.15016.2 0.000701 16-Sep H.VPIILVGNK[136.11].A "sp|O75628|REM1_HUMAN,sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,sp|Q8IXI1|MIRO2_HUMAN,sp|P55042|RAD_HUMAN,sp|Q9Y3L5|RAP2C_HUMAN,tr|I3L2C6|I3L2C6_HUMAN,tr|H3BST5|H3BST5_HUMAN,tr|A0A087X2C3|A0A087X2C3_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 16 959.6259 2.17 21112 15016 2 959.626101 480.8202 GTP-binding protein REM 1 OS=Homo sapiens OX=9606 GN=REM1 PE=1 SV=2 8.72 3167.1 - 319809 - - - 0.2063 - 1.861 0.215 - 232.6 1 1 0 0.0002 9 0 0 0 8.84E+07 4.08E+07 - - - 2.4258 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.15020.15020.2 0.0123 16-Oct R.ILDSAEFIK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1034.5648 0.95 21115 15020 2 1034.56535 518.2897 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3167.6 - 4.02E+07 - - - 0.52 - 2.009 0.424 - 228.9 1 2 0 0.0005 9 0 0 0 7.68E+09 8.13E+09 - - - 4.1908 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.15025.15025.2 0.0014 18-Nov R.ILALEADMTK.W "sp|Q4VCS5|AMOT_HUMAN,sp|Q9Y2J4|AMOL2_HUMAN,sp|Q8IY63|AMOL1_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 5 1103.5896 3.32 21119 15025 2 1103.591694 552.8021 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.37 3168.2 - 891018 - - - 1.8549 - 2.028 0.408 - 263.4 1 2 0 0.002 10 0 0 0 2.03E+07 6.11E+06 - - - 4.0274 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15026.15026.2 0.00182 14-Sep R.LLEIVSYK.L "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 963.5641 0.92 21120 15026 2 963.564862 482.7893 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6 3168.3 - 872483 - - - 0.8074 - 1.733 0.378 - 218.2 1 2 0 0.0008 8 0 0 0 7.16E+07 7.82E+07 - - - 3.491 0.8905 230117_WJC_METTL3_WT_vs_EV_F03.15037.15037.2 0.494 14-Sep R.PIVTVWER.E "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EQR8|K7EQR8_HUMAN" 3 998.5549 2.17 21127 15037 2 998.556608 500.2847 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 6.43 3169.7 - 3.92E+06 - - - 1.6944 - 1.739 0.172 - 199.4 1 1 0 0.0017 8 0 0 0 1.05E+08 4.82E+07 - - - 1.9796 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.15040.15040.2 0.106 14-Aug R.VGEIVVFR[166.11].L "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 927.5417 1.97 21128 15040 2 927.543793 464.7781 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.97 3170.1 - 2.62E+06 - - - 2.2328 - 1.551 0.348 - 224.4 1 2 0 0.0021 8 0 0 0 6.67E+07 3.39E+07 - - - 2.9344 0.875 230117_WJC_METTL3_WT_vs_EV_F03.15044.15044.2 6.96 12-May R.QMSLLLR[166.11].R sp|P25705|ATPA_HUMAN 1 869.5032 0.73 21132 15044 2 869.506037 435.7589 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 9.75 3170.6 - 364142 - - - 3.2306 - 1.181 0.02 - 66.7 11 2 0 0.0028 7 0 0 0 8.87E+06 1.21E+07 - - - -0.7502 1 230117_WJC_METTL3_WT_vs_EV_F03.15053.15053.2 5.18E-05 13/28 R.NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1656.8459 1.9 21139 15053 2 1656.848669 829.4302 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3171.7 - 298385 - - - 1.6694 - 2.537 0.524 - 353.6 1 2 0 0.0028 15 0 0 0 1.10E+07 5.77E+06 - - - 5.1993 1 230117_WJC_METTL3_WT_vs_EV_F03.15054.15054.2 3.14E-09 15/28 R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 0.83 21140 15054 2 1646.839164 824.4261 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3171.9 - 250647 - - - 0.9297 - 2.696 0.529 - 786.3 1 2 0 0.0015 15 0 0 0 4.07E+06 4.89E+06 - - - 5.386 0.995 230117_WJC_METTL3_WT_vs_EV_F03.15057.15057.2 0.174 12-Aug K.MDLLLTK[136.11].T "sp|Q6P3W7|SCYL2_HUMAN,tr|H0YIK6|H0YIK6_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 840.487 0.94 21141 15057 2 840.487535 421.2508 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.59 3172.3 - 4.86E+06 - - - 0.6056 - 1.439 0.118 - 214.2 1 2 0 0.0005 7 0 0 0 6.36E+07 6.74E+07 - - - 1.0656 0.9955 230117_WJC_METTL3_WT_vs_EV_F03.15059.15059.2 1.73 12-Jun R.LIVDVIR.F "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 826.5276 1.15 21143 15059 2 826.528416 414.2711 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.84 3172.5 - 987979 - - - 0.9401 - 1.182 0.204 - 112.9 1 2 0 0.0008 7 0 0 0 6.43E+07 5.61E+07 - - - 1.0773 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.15060.15060.2 0.525 14-Oct K.GAIEVLIR[166.11].E "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 879.5417 1.02 21144 15060 2 879.544074 440.7781 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 6 3172.6 - 926480 - - - 2.6741 - 2.112 0.184 - 266.3 1 2 0 0.0024 8 0 0 0 3.43E+07 3.35E+07 - - - 2.6541 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.15061.15061.2 1.37 14-Sep K.GAIEVLIR.E "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 869.5335 1.05 21145 15061 2 869.535762 435.774 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 6 3172.7 - 867314 - - - 2.6566 - 1.728 0.204 - 230.8 1 2 0 0.0023 8 0 0 0 3.43E+07 3.27E+07 - - - 2.1966 0.9873 230117_WJC_METTL3_WT_vs_EV_F03.15069.15069.2 0.782 16-Aug K.ANPALYVLR[166.11].E sp|Q6P2Q9|PRP8_HUMAN 1 1025.5897 1.43 21151 15069 2 1025.590616 513.8021 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.79 3173.7 - 1.06E+06 - - - 0.859 - 1.176 0.113 - 133 1 2 0 0.0009 9 0 0 0 8.32E+07 5.81E+07 - - - 0.3444 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.15076.15076.2 0.00915 14-Sep R.VGEIVVFR.L "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 917.5335 1.96 21156 15076 2 917.534414 459.774 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.97 3174.5 - 1.68E+06 - - - 1.0485 - 1.981 0.388 - 302.9 1 2 0 0.001 8 0 0 0 6.68E+07 3.41E+07 - - - 3.9682 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.15077.15077.2 0.0357 14-Jul K.FLVGFTNK[136.11].G "sp|P43307|SSRA_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|C9J5W0|C9J5W0_HUMAN" 6 932.5211 1.5 21157 15077 2 932.521749 467.2678 Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3 8.75 3174.6 - 989274 - - - 0.6927 - 1.53 0.37 - 134.8 1 2 0 0.0006 8 0 0 0 2.15E+08 1.44E+08 - - - 3.0562 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.15078.15078.2 0.102 12-Sep R.QMSLLLR.R sp|P25705|ATPA_HUMAN 1 859.495 1.51 21158 15078 2 859.497652 430.7548 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 9.75 3174.8 - 939284 - - - 3.1344 - 1.613 0.169 - 296.4 1 2 0 0.0027 7 0 0 0 2.19E+08 1.45E+08 - - - 1.8033 0.9882 230117_WJC_METTL3_WT_vs_EV_F03.15080.15080.2 0.125 16-Aug K.MLLYTEVTR[166.11].Y "sp|P31150|GDIA_HUMAN,sp|P50395|GDIB_HUMAN,tr|G5E9U5|G5E9U5_HUMAN,tr|Q5SX86|Q5SX86_HUMAN,tr|Q5SX90|Q5SX90_HUMAN,tr|V9GYF8|V9GYF8_HUMAN,tr|V9GYJ7|V9GYJ7_HUMAN" 7 1134.5983 1.22 21160 15080 2 1134.596577 568.3064 Rab GDP dissociation inhibitor alpha OS=Homo sapiens OX=9606 GN=GDI1 PE=1 SV=2 5.75 3175 - 199659 - - - -1.4754 - 1.321 0.199 - 250.5 1 2 0 -0.0017 9 0 0 0 2.07E+07 1.70E+07 - - - 1.3157 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.15086.15086.2 0.00436 18-Sep R.FLSTTIVYPK[136.11].Y sp|Q8N5W9|RFLB_HUMAN 1 1175.6682 2.21 21164 15086 2 1175.672492 588.8414 Refilin-B OS=Homo sapiens OX=9606 GN=RFLNB PE=1 SV=1 8.59 3175.8 - 343309 - - - 3.683 - 1.445 0.331 - 190.8 1 2 0 0.0043 10 0 0 0 1.05E+07 4.73E+06 - - - 2.5119 0.9794 230117_WJC_METTL3_WT_vs_EV_F03.15087.15087.2 6.7 12-Jun R.LIVDVIR[166.11].F "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 836.5359 1.18 21165 15087 2 836.538206 419.2752 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.84 3175.9 - 3.79E+06 - - - 2.7458 - 1.396 0.054 - 119.9 3 2 0 0.0023 7 0 0 0 6.39E+07 5.42E+07 - - - 0.2831 0.9732 230117_WJC_METTL3_WT_vs_EV_F03.15090.15090.2 1.15 12-Jul K.TLLDSLR.S sp|Q5JTH9|RRP12_HUMAN 1 816.4705 0.69 21168 15090 2 816.47381 409.2425 RRP12-like protein OS=Homo sapiens OX=9606 GN=RRP12 PE=1 SV=2 5.5 3176.3 - 817699 - - - 4.032 - 1.429 0.067 - 201.5 1 2 0 0.0033 7 0 0 0 2.55E+07 3.71E+07 - - - 0.6659 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.15098.15098.2 0.00122 16-Oct R.AFGYYGPLR[166.11].S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1052.5319 1.01 21175 15098 2 1052.533016 527.2732 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3177 - 1.29E+06 - - - 1.0736 - 2.06 0.451 - 445.1 1 2 0 0.0011 9 0 0 0 1.33E+09 1.32E+09 - - - 4.4626 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.15099.15099.2 0.000317 16-Sep R.AFGYYGPLR.S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1042.5236 1.01 21176 15099 2 1042.525328 522.2691 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3177.1 - 883872 - - - 1.6422 - 1.452 0.374 - 286.7 1 2 0 0.0017 9 0 0 0 1.33E+09 1.32E+09 - - - 2.8818 0.9605 230117_WJC_METTL3_WT_vs_EV_F03.15100.15100.2 4.06 16-Jul R.VGVAAVGNR[166.11].L "sp|Q6TDP4|KLH17_HUMAN,tr|Q0VGE6|Q0VGE6_HUMAN" 2 851.4853 0.93 21177 15100 2 851.487293 426.7499 Kelch-like protein 17 OS=Homo sapiens OX=9606 GN=KLHL17 PE=1 SV=1 9.72 3177.2 - 841118 - - - 2.3758 - 1.408 0.005 - 128.6 6 2 0 0.002 9 0 0 0 4.89E+07 5.24E+07 - - - -0.2804 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.15105.15105.2 0.459 14-Jul K.LLIESLEK.Y "sp|Q8TC07|TBC15_HUMAN,tr|F8VV61|F8VV61_HUMAN,tr|C9JA93|C9JA93_HUMAN" 3 943.559 2.01 21180 15105 2 943.560234 472.7868 TBC1 domain family member 15 OS=Homo sapiens OX=9606 GN=TBC1D15 PE=1 SV=2 4.53 3177.9 - 1.21E+06 - - - 1.3089 - 1.552 0.202 - 103.5 1 2 0 0.0012 8 0 0 0 2.13E+07 1.06E+07 - - - 1.8582 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.15107.15107.2 0.0024 18-Aug R.FLSTTIVYPK.Y sp|Q8N5W9|RFLB_HUMAN 1 1167.654 2.21 21182 15107 2 1167.659125 584.8343 Refilin-B OS=Homo sapiens OX=9606 GN=RFLNB PE=1 SV=1 8.59 3178.1 - 695029 - - - 4.4217 - 1.514 0.408 - 142.9 1 2 0 0.0052 10 0 0 0 1.05E+07 4.73E+06 - - - 3.2106 0.9778 230117_WJC_METTL3_WT_vs_EV_F03.15115.15115.2 0.333 16-May R.LLLPTPTVK[136.11].Q "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 988.6412 2.44 21188 15115 2 988.642801 495.3279 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 3179 - 778701 - - - 1.6012 - 0.954 0.177 - 58.6 4 2 0 0.0016 9 0 0 0 3.91E+08 1.60E+08 - - - -0.0574 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15116.15116.2 1.70E-05 20-Sep R.VFSGLVSTGLK.V sp|P13639|EF2_HUMAN 1 1106.6336 4.01 21189 15116 2 1106.635119 554.3241 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.72 3179.1 - 393430 - - - 1.4088 - 1.889 0.381 - 219.6 1 2 0 0.0016 11 0 0 0 1.03E+08 2.57E+07 - - - 3.5752 0.999 230117_WJC_METTL3_WT_vs_EV_F03.15120.15120.2 0.116 16-Sep R.LLLPTPTVK.Q "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 980.627 2.44 21191 15120 2 980.628619 491.3208 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 3179.6 - 1.32E+06 - - - 1.6326 - 1.665 0.256 - 258.9 1 2 0 0.0016 9 0 0 0 3.91E+08 1.60E+08 - - - 2.4063 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.15121.15121.2 0.00215 16-Oct R.LLGYVATLK.D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 976.5957 2.36 21192 15121 2 976.599598 489.3051 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 8.59 3179.7 - 1.49E+06 - - - 3.973 - 1.902 0.386 - 212.3 1 2 0 0.0039 9 0 0 0 3.34E+08 1.41E+08 - - - 3.7507 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.15122.15122.2 0.0129 18-Oct K.FGVVVVGVGR.A "sp|P53004|BIEA_HUMAN,tr|C9J1E1|C9J1E1_HUMAN" 2 987.5866 1.22 21193 15122 2 987.588383 494.8006 Biliverdin reductase A OS=Homo sapiens OX=9606 GN=BLVRA PE=1 SV=2 9.75 3179.9 - 756567 - - - 1.855 - 1.771 0.298 - 208 1 2 0 0.0018 10 0 0 0 1.67E+07 1.37E+07 - - - 2.8368 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.15123.15123.2 0.00019 20-Sep R.VFSGLVSTGLK[136.11].V sp|P13639|EF2_HUMAN 1 1114.6478 3.63 21194 15123 2 1114.649571 558.3312 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.72 3180 - 298018 - - - 1.6247 - 1.639 0.405 - 152.7 1 2 0 0.0018 11 0 0 0 9.34E+07 2.57E+07 - - - 3.3684 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.15131.15131.2 0.048 16-Sep R.LLGYVATLK[136.11].D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 984.6099 2.36 21199 15131 2 984.612713 493.3122 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 8.59 3181 - 1.88E+06 - - - 2.8387 - 1.699 0.283 - 156.7 1 2 0 0.0028 9 0 0 0 3.34E+08 1.41E+08 - - - 2.6638 1 230117_WJC_METTL3_WT_vs_EV_F03.15137.15137.2 3.37E-05 16-Nov K.YMAC[160.03]C[160.03]LLYR.G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1248.5454 3.01 21203 15137 2 1248.546482 625.28 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3181.7 - 595554 - - - 0.9018 - 1.79 0.596 - 486.8 1 2 0 0.0011 9 0 0 0 2.35E+08 7.82E+07 - - - 5.1271 1 230117_WJC_METTL3_WT_vs_EV_F03.15139.15139.2 7.99E-05 16-Oct K.YMAC[160.03]C[160.03]LLYR[166.11].G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1258.5536 3.01 21205 15139 2 1258.557051 630.2841 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3181.9 - 241809 - - - 2.7214 - 1.796 0.595 - 371.1 1 2 0 0.0034 9 0 0 0 2.35E+08 7.82E+07 - - - 5.1287 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15147.15147.2 0.00523 13/20 R.IALTDNALIAR[166.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1179.6851 0.85 21210 15147 2 1179.686874 590.8498 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3182.8 - 511329 - - - 1.5106 - 2.41 0.285 - 537.8 1 2 0 0.0018 11 0 0 0 2.37E+07 2.78E+07 - - - 3.525 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15150.15150.2 0.00332 14-Aug K.AFAMIIDK.L "sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BND9|H3BND9_HUMAN" 8 907.4837 2.55 21212 15150 2 907.484694 454.7491 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 5.88 3183.2 - 2.07E+06 - - - 1.0678 - 1.565 0.453 - 255.3 1 2 0 0.001 8 0 0 0 9.16E+07 3.58E+07 - - - 3.7374 0.9877 230117_WJC_METTL3_WT_vs_EV_F03.15153.15153.2 2.91 12-Jun K.NLILVVR.G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 825.5436 1.15 21214 15153 2 825.543995 413.7791 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3183.4 - 6.29E+06 - - - 0.4506 - 1.353 0.061 - 148.4 1 2 0 0.0004 7 0 0 0 1.69E+08 1.48E+08 - - - 0.4494 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15154.15154.2 0.000977 20-Sep R.IALTDNALIAR.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1169.6768 0.85 21215 15154 2 1169.678493 585.8457 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3183.6 - 722612 - - - 1.4286 - 1.983 0.373 - 186.6 1 2 0 0.0017 11 0 0 0 2.37E+07 2.78E+07 - - - 3.6475 0.9776 230117_WJC_METTL3_WT_vs_EV_F03.15168.15168.2 0.608 16-Sep K.LVELPYTVK.G sp|Q9NPF4|OSGEP_HUMAN 1 1060.6168 3.46 21222 15168 2 1060.618235 531.3157 Probable tRNA N6-adenosine threonylcarbamoyltransferase OS=Homo sapiens OX=9606 GN=OSGEP PE=1 SV=1 6 3185.4 - 1.16E+06 - - - 1.3077 - 0.959 0.136 - 178.1 1 2 0 0.0014 9 0 0 0 2.62E+07 7.57E+06 - - - -0.0761 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.15171.15171.2 0.00871 12-Jun K.EILFYDR.L sp|Q08J23|NSUN2_HUMAN 1 954.4811 1.8 21224 15171 2 954.482023 478.2478 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.37 3185.7 - 3.41E+06 - - - 0.9859 - 1.344 0.366 - 186.8 1 2 0 0.0009 7 0 0 0 1.20E+08 6.68E+07 - - - 2.6808 0.9937 230117_WJC_METTL3_WT_vs_EV_F03.15172.15172.2 0.758 12-Jun K.EILFYDR[166.11].L sp|Q08J23|NSUN2_HUMAN 1 964.4894 1.8 21225 15172 2 964.489716 483.252 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.37 3185.8 - 1.71E+06 - - - 0.3774 - 1.267 0.157 - 130.4 1 2 0 0.0004 7 0 0 0 1.20E+08 6.68E+07 - - - 0.9503 0.9812 230117_WJC_METTL3_WT_vs_EV_F03.15191.15191.2 0.108 16-Aug R.LPEAAFLAR.T "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 986.5549 2.61 21234 15191 2 986.553885 494.2847 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 6 3188.1 - 2.83E+06 - - - -1.0451 - 1.313 0.124 - 116.7 1 2 0 -0.001 9 0 0 0 1.81E+08 6.94E+07 - - - 0.7444 0.9962 230117_WJC_METTL3_WT_vs_EV_F03.15192.15192.2 0.00834 12-Jun R.FLTVMMK.H "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 868.4551 1.29 21235 15192 2 868.456056 435.2348 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.75 3188.2 - 2.41E+06 - - - 1.1388 - 1.283 0.184 - 121.7 1 2 0 0.001 7 0 0 0 2.07E+08 1.61E+08 - - - 1.1893 0.997 230117_WJC_METTL3_WT_vs_EV_F03.15193.15193.2 0.0666 12-Jul R.FLTVMMK[136.11].H "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 876.4693 1.29 21236 15193 2 876.468913 439.2419 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.75 3188.3 - 2.35E+06 - - - -0.4039 - 1.28 0.284 - 153 1 2 0 -0.0004 7 0 0 0 2.07E+08 1.60E+08 - - - 1.9207 0.987 230117_WJC_METTL3_WT_vs_EV_F03.15207.15207.2 1.65 12-Aug K.YAWVLDK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 14 893.4647 1.97 21242 15207 2 893.466031 447.7396 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 3190.1 - 1.24E+06 - - - 1.4852 - 1.413 0.021 - 205.3 1 2 0 0.0013 7 0 0 0 8.30E+07 4.21E+07 - - - 0.2911 0.967 230117_WJC_METTL3_WT_vs_EV_F03.15210.15210.2 0.0433 22-Jun K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.22 21245 15210 2 1287.762354 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3190.5 - 0 - - - 3.4875 - 1.358 0.057 - 72.5 1 2 0 0.0045 12 0 0 0 1.07E+08 8.78E+07 - - - 0.2658 0.8536 230117_WJC_METTL3_WT_vs_EV_F03.15214.15214.2 2.08 16-Mar K.DDAGLPPPK.A sp|O43909|EXTL3_HUMAN 1 908.4603 2.48 21247 15214 2 908.464615 455.2374 Exostosin-like 3 OS=Homo sapiens OX=9606 GN=EXTL3 PE=1 SV=1 4.21 3191.1 - 1.34E+06 - - - 4.6981 - 0.976 0.182 - 27.7 18 2 0 0.0043 9 0 0 0 3.48E+07 1.40E+07 - - - -0.2471 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.15217.15217.2 0.00531 14-Aug K.LIINSLYK.N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 962.5801 0.96 21248 15217 2 962.580056 482.2973 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3191.5 - 4.75E+06 - - - -0.0125 - 1.632 0.299 - 153.8 1 2 0 0 8 0 0 0 1.49E+08 1.56E+08 - - - 2.7266 0.985 230117_WJC_METTL3_WT_vs_EV_F03.15220.15220.2 3.14 14-Jun K.VLAC[160.03]PFLR.E sp|Q709C8|VP13C_HUMAN 1 974.5372 0.16 21250 15220 2 974.537945 488.2759 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 8.22 3191.8 - 867803 - - - 0.8076 - 1.402 0.066 - 60.4 5 2 0 0.0008 8 0 0 0 2.51E+07 1.55E+08 - - - 0.2351 0.988 230117_WJC_METTL3_WT_vs_EV_F03.15229.15229.2 1.98 14-Aug K.LIINSLYK[136.11].N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 970.5943 0.96 21255 15229 2 970.594161 486.3044 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3192.9 - 5.33E+06 - - - -0.1102 - 1.156 0.16 - 96.5 1 2 0 -0.0001 8 0 0 0 1.49E+08 1.56E+08 - - - 0.6599 0.9811 230117_WJC_METTL3_WT_vs_EV_F03.15232.15232.2 1.28 12-Jun K.LVFDGLR[166.11].K sp|P15924|DESP_HUMAN 1 828.4733 46.46 21258 15232 2 828.474192 415.2439 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.84 3193.1 - 1.21E+06 - - - 1.067 - 1.154 0.075 - 109.3 1 2 0 0.0009 7 0 0 0 1.54E+09 3.32E+07 - - - 0.0485 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.15234.15234.2 0.000408 22-Sep K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.79 21260 15234 2 1277.751016 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3193.4 - 252565 - - - 1.1137 - 1.688 0.352 - 165.2 1 2 0 0.0014 12 0 0 0 7.91E+06 4.41E+06 - - - 3.018 0.8948 230117_WJC_METTL3_WT_vs_EV_F03.15238.15238.2 2.32 20-Jun R.GVGAGLEAAER[166.11].E sp|O00291|HIP1_HUMAN 1 1038.5333 1.51 21261 15238 2 1038.531302 520.2739 Huntingtin-interacting protein 1 OS=Homo sapiens OX=9606 GN=HIP1 PE=1 SV=5 4.53 3193.9 - 4.95E+06 - - - -1.9653 - 1.356 0.007 - 77.1 1 2 0 -0.002 11 0 0 0 9.25E+07 6.11E+07 - - - -0.0841 0.955 230117_WJC_METTL3_WT_vs_EV_F03.15259.15259.2 2.52 18-May R.LVQAFQFTDK.H "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 3 1195.6237 2.8 21277 15259 2 1195.62766 598.8191 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.84 3196.6 - 326677 - - - 3.292 - 1.088 0.123 - 39.2 3 2 0 0.0039 10 0 0 0 5.05E+06 1.81E+06 - - - -0.0295 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.15264.15264.2 0.00314 16-Aug R.YLYLSTMER.S "sp|Q10570|CPSF1_HUMAN,tr|A0A087X101|A0A087X101_HUMAN" 2 1174.5692 0.87 21280 15264 2 1174.57142 588.2919 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6 3197.3 - 213507 - - - 1.8509 - 1.532 0.369 - 198.4 1 2 0 0.0022 9 0 0 0 3.87E+06 4.45E+06 - - - 2.9999 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.15265.15265.2 0.171 18-Oct K.IVLLSANSIR.A "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 1084.6604 2 21281 15265 2 1084.661829 543.3375 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 9.75 3197.4 - 1.38E+06 - - - 1.2769 - 1.703 0.309 - 304.8 1 2 0 0.0014 10 0 0 0 2.35E+07 1.17E+07 - - - 2.8089 1 230117_WJC_METTL3_WT_vs_EV_F03.15266.15266.2 2.10E-07 14/22 K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 45.62 21282 15266 2 1356.690407 679.3515 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3197.5 - 724072 - - - 1.399 - 2.872 0.389 - 886.5 1 2 0 0.0019 12 0 0 0 1.39E+07 3.04E+05 - - - 4.6895 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.15271.15271.2 8.65E-06 20-Nov R.AVAQALEVIPR.T "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1165.6819 999 21285 15271 2 1165.679134 583.8482 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.05 3198.2 - 96475.6 - - - -2.3797 - 2.305 0.398 - 363.9 1 2 0 -0.0028 11 0 0 0 1.77E+06 0.00E+00 - - - 4.2388 0.9535 230117_WJC_METTL3_WT_vs_EV_F03.15272.15272.2 9.54 12-Apr K.GELANFR.F "sp|Q9Y6D6|BIG1_HUMAN,sp|Q9Y6D5|BIG2_HUMAN,tr|A0A7P0T7Z2|A0A7P0T7Z2_HUMAN,tr|A0A7P0T9L9|A0A7P0T9L9_HUMAN,tr|A0A7P0TA34|A0A7P0TA34_HUMAN,tr|E5RIF2|E5RIF2_HUMAN,tr|E5RHL7|E5RHL7_HUMAN" 7 805.4083 2.17 21286 15272 2 805.408892 403.7114 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens OX=9606 GN=ARFGEF1 PE=1 SV=2 6 3198.3 - 200218 - - - 0.7946 - 0.969 0.117 - 39.6 5 2 0 0.0006 7 0 0 0 5.46E+06 2.52E+06 - - - -0.507 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.15277.15277.2 2.98E-05 14-Sep R.FADFTVYR[166.11].N "sp|Q9NY61|AATF_HUMAN,tr|A0A7P0T868|A0A7P0T868_HUMAN,tr|A0A7P0TAR0|A0A7P0TAR0_HUMAN,tr|A0A7P0TBI0|A0A7P0TBI0_HUMAN,tr|A0A7P0Z4P2|A0A7P0Z4P2_HUMAN,tr|A0A7P0Z4N2|A0A7P0Z4N2_HUMAN,tr|A0A087WTH8|A0A087WTH8_HUMAN,tr|A0A7P0Z434|A0A7P0Z434_HUMAN" 8 1027.5003 1.01 21289 15277 2 1027.502353 514.7574 Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1 5.84 3198.9 - 1.24E+06 - - - 2.0448 - 1.699 0.483 - 251.5 1 2 0 0.0021 8 0 0 0 2.07E+07 2.04E+07 - - - 4.2064 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.15279.15279.2 0.000426 16-Sep R.LLVHMGLLK.S sp|P46060|RAGP1_HUMAN 1 1022.6311 1.52 21291 15279 2 1022.631719 512.3228 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 8.76 3199.2 - 141960 - - - 0.6464 - 1.382 0.446 - 152.8 1 2 0 0.0007 9 0 0 0 4.98E+06 3.27E+06 - - - 3.2709 0.996 230117_WJC_METTL3_WT_vs_EV_F03.15288.15288.2 0.159 12-Aug R.IYLYLTK.V "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 912.5321 1.76 21296 15288 2 912.533799 457.2733 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.5 3200.2 - 1.50E+06 - - - 1.9112 - 1.628 0.083 - 236 1 2 0 0.0017 7 0 0 0 5.69E+07 3.23E+07 - - - 1.1977 0.9944 230117_WJC_METTL3_WT_vs_EV_F03.15296.15296.2 0.0913 14-Aug R.LLLNYAVR.L "sp|Q92989|CLP1_HUMAN,tr|E9PL17|E9PL17_HUMAN,tr|E9PKV5|E9PKV5_HUMAN" 3 960.5757 2.71 21302 15296 2 960.578677 481.2951 Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1 8.75 3201.3 - 295788 - - - 3.1492 - 1.517 0.154 - 173.3 1 2 0 0.003 8 0 0 0 1.52E+07 5.62E+06 - - - 1.4343 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.15298.15298.2 0.000736 14-Sep R.NIVLYDMR.Q "sp|Q9NV06|DCA13_HUMAN,tr|A0A087WT20|A0A087WT20_HUMAN,tr|A0A087X1F8|A0A087X1F8_HUMAN" 3 1022.5219 999 21304 15298 2 1022.526764 512.2682 DDB1- and CUL4-associated factor 13 OS=Homo sapiens OX=9606 GN=DCAF13 PE=1 SV=2 5.84 3201.5 - 282973 - - - 4.7559 - 1.619 0.377 - 273.7 1 2 0 0.0049 8 0 0 0 8.79E+06 0.00E+00 - - - 3.2771 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.15300.15300.2 2.32E-05 18-Aug R.LITLEEEMTK.Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1205.6213 3.18 21306 15300 2 1205.628159 603.8179 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3201.8 - 113814 - - - 5.6552 - 1.866 0.5 - 152.3 1 2 0 0.0068 10 0 0 0 2.82E+07 8.88E+06 - - - 4.4731 0.9546 230117_WJC_METTL3_WT_vs_EV_F03.15303.15303.2 0.0656 16-Jun K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 66.57 21307 15303 2 1014.541572 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3202.2 - 7.07E+06 - - - 6.8968 - 1.43 0.227 - 73 1 2 0 0.007 9 0 0 0 1.97E+08 2.96E+06 - - - 1.7502 1 230117_WJC_METTL3_WT_vs_EV_F03.15304.15304.2 0.00326 16-Dec R.PAVLSGYFK.Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 980.5331 1.06 21308 15304 2 980.535487 491.2738 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.01 3202.3 - 1.81E+06 - - - 2.416 - 2.111 0.475 - 538.9 1 1 0 0.0024 9 0 0 0 1.65E+08 1.56E+08 - - - 4.7102 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.15305.15305.2 0.597 12-Jul K.FLLLQQK[136.11].Y "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 896.5575 2.07 21309 15305 2 896.558993 449.286 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 8.75 3202.3 - 836894 - - - 1.6775 - 1.339 0.217 - 155.5 1 2 0 0.0015 7 0 0 0 6.32E+07 3.05E+07 - - - 1.5683 0.9821 230117_WJC_METTL3_WT_vs_EV_F03.15310.15310.2 0.701 12-May R.QPVILWK.E sp|Q9UKN8|TF3C4_HUMAN 1 882.5327 0.81 21313 15310 2 882.534933 442.2736 General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2 8.75 3202.9 - 684240 - - - 2.503 - 1.058 0.163 - 93.3 2 2 0 0.0022 7 0 0 0 1.29E+07 1.59E+07 - - - 0.2884 0.993 230117_WJC_METTL3_WT_vs_EV_F03.15312.15312.2 0.132 12-Jul K.SEFVILR.D "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 862.4913 1.04 21314 15312 2 862.494626 432.2529 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 5.72 3203.1 - 743015 - - - 3.9108 - 1.461 0.193 - 206.5 1 2 0 0.0034 7 0 0 0 6.58E+07 6.33E+07 - - - 1.6667 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.15313.15313.2 0.0533 12-Jul K.SEFVILR[166.11].D "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 872.4995 1.04 21315 15313 2 872.501225 437.257 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 5.72 3203.3 - 554317 - - - 1.9507 - 1.526 0.173 - 283.4 1 2 0 0.0017 7 0 0 0 6.58E+07 6.33E+07 - - - 1.6574 0.9916 230117_WJC_METTL3_WT_vs_EV_F03.15314.15314.2 0.29 12-Aug R.WGGLDLR[166.11].R sp|Q9H7N4|SFR19_HUMAN 1 825.4373 0.93 21316 15314 2 825.438839 413.7259 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.84 3203.3 - 2.00E+06 - - - 1.9166 - 1.318 0.099 - 263 1 2 0 0.0016 7 0 0 0 4.69E+07 5.06E+07 - - - 0.6466 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.15315.15315.2 0.0318 12-Jul R.WFVTC[160.03]VR.Q "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN,tr|A0A140T954|A0A140T954_HUMAN" 3 966.4746 0.81 21317 15315 2 966.476822 484.2446 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 8.25 3203.4 - 343793 - - - 2.3425 - 1.241 0.387 - 131.6 1 2 0 0.0023 7 0 0 0 1.08E+07 1.33E+07 - - - 2.5828 0.9898 230117_WJC_METTL3_WT_vs_EV_F03.15319.15319.2 0.355 12-Aug R.WGGLDLR.R sp|Q9H7N4|SFR19_HUMAN 1 815.429 0.75 21319 15319 2 815.432159 408.7218 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.84 3204 - 1.66E+06 - - - 3.89 - 1.322 0.191 - 297.5 1 2 0 0.0032 7 0 0 0 4.79E+07 6.37E+07 - - - 1.3352 0.9532 230117_WJC_METTL3_WT_vs_EV_F03.15322.15322.2 0.728 12-Jul K.LQQLWLK.A "sp|Q9NPC8|SIX2_HUMAN,sp|Q15475|SIX1_HUMAN" 2 927.5542 1.96 21322 15322 2 927.557003 464.7844 Homeobox protein SIX2 OS=Homo sapiens OX=9606 GN=SIX2 PE=1 SV=1 8.75 3204.2 - 603752 - - - 3.0349 - 1.303 0.013 - 109.2 2 2 0 0.0028 7 0 0 0 2.59E+07 1.32E+07 - - - -0.1597 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.15323.15323.2 0.159 18-Sep K.LVIIEGDLER.T "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1155.6499 1.3 21323 15323 2 1155.652639 578.8322 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.14 3204.3 - 448047 - - - 2.3363 - 1.839 0.272 - 295 1 2 0 0.0027 10 0 0 0 2.57E+07 1.97E+07 - - - 2.7497 0.9932 230117_WJC_METTL3_WT_vs_EV_F03.15327.15327.2 0.261 16-Aug R.ALVQSLLAK.E sp|Q9NX46|ADPRS_HUMAN 1 941.591 3.16 21327 15327 2 941.594693 471.8028 ADP-ribose glycohydrolase ARH3 OS=Homo sapiens OX=9606 GN=ADPRS PE=1 SV=1 8.8 3204.8 - 188979 - - - 3.9571 - 1.464 0.213 - 127 1 2 0 0.0037 9 0 0 0 1.49E+07 4.71E+06 - - - 1.7158 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.15331.15331.2 0.0162 14-Jul K.NVPYVFVR.S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 992.5444 0.87 21330 15331 2 992.547239 497.2795 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3205.3 - 5.67E+06 - - - 2.9097 - 1.446 0.424 - 202 1 2 0 0.0029 8 0 0 0 1.49E+08 1.72E+08 - - - 3.284 0.9897 230117_WJC_METTL3_WT_vs_EV_F03.15332.15332.2 3.3 12-Aug R.IYLYLTK[136.11].V "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 920.5463 1.83 21331 15332 2 920.548205 461.2804 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.5 3205.4 - 1.19E+06 - - - 2.1183 - 1.419 0.055 - 215.3 1 2 0 0.0019 7 0 0 0 5.68E+07 3.10E+07 - - - 0.5555 0.9832 230117_WJC_METTL3_WT_vs_EV_F03.15334.15334.2 0.296 14-Jul K.LGFESIYK.L "sp|P49643|PRI2_HUMAN,tr|A0A5F9ZHU7|A0A5F9ZHU7_HUMAN" 2 955.5015 1.95 21333 15334 2 955.505106 478.758 DNA primase large subunit OS=Homo sapiens OX=9606 GN=PRIM2 PE=1 SV=2 6 3205.6 - 1.32E+06 - - - 3.7907 - 1.447 0.1 - 103.6 1 2 0 0.0036 8 0 0 0 1.91E+07 9.80E+06 - - - 0.8928 0.9528 230117_WJC_METTL3_WT_vs_EV_F03.15336.15336.2 1.97 14-Jul R.LFIGGIPK.M "sp|A0AV96|RBM47_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6REZ6|D6REZ6_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 5 843.5218 1.28 21335 15336 2 843.526463 422.7682 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 8.75 3205.7 - 884040 - - - 5.4984 - 1.45 0.11 - 127.7 1 2 0 0.0046 8 0 0 0 5.39E+07 4.20E+07 - - - 0.9726 0.999 230117_WJC_METTL3_WT_vs_EV_F03.15337.15337.2 1.97E-05 18-Oct R.LITLEEEMTK[136.11].Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1213.6355 3.22 21336 15337 2 1213.640194 607.825 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3205.9 - 419022 - - - 3.8339 - 1.654 0.493 - 276.3 1 2 0 0.0047 10 0 0 0 2.82E+07 8.75E+06 - - - 4.0854 0.85 230117_WJC_METTL3_WT_vs_EV_F03.15338.15338.2 0.0384 16-Aug V.ILQTLPQLR.L "sp|Q9C099|LRCC1_HUMAN,sp|Q5T4S7|UBR4_HUMAN,tr|A0A0A0MSW0|A0A0A0MSW0_HUMAN,tr|X6RE05|X6RE05_HUMAN" 4 1080.6655 0.62 21337 15338 2 1080.668328 541.34 Leucine-rich repeat and coiled-coil domain-containing protein 1 OS=Homo sapiens OX=9606 GN=LRRCC1 PE=1 SV=2 9.75 3206 - 273460 - - - 2.5901 - 1.593 0.213 - 163 1 1 0 0.0028 9 0 0 0 1.22E+07 1.97E+07 - - - 1.9604 0.9914 230117_WJC_METTL3_WT_vs_EV_F03.15342.15342.2 0.148 12-Jul R.LIMQYLK[136.11].E sp|Q2TAY7|SMU1_HUMAN 1 915.5343 0.96 21339 15342 2 915.535934 458.7744 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.59 3206.5 - 1.30E+06 - - - 1.7727 - 1.269 0.11 - 130.4 1 2 0 0.0016 7 0 0 0 6.85E+07 7.14E+07 - - - 0.6078 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.15357.15357.2 0.00785 16-Oct K.LGEWVGLC[160.03]K[136.11].L sp|P25398|RS12_HUMAN 1 1068.5518 2.19 21349 15357 2 1068.554128 535.2832 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3208.4 - 4.72E+06 - - - 2.2236 - 1.997 0.445 - 368.9 1 2 0 0.0024 9 0 0 0 3.69E+08 1.68E+08 - - - 4.328 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.15358.15358.2 0.0542 18-Jun K.VLFTGVVDAR[166.11].G sp|Q14676|MDC1_HUMAN 1 1085.6109 2.28 21350 15358 2 1085.611848 543.8127 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 5.81 3208.5 - 510181 - - - 0.9055 - 1.435 0.282 - 76.9 1 2 0 0.001 10 0 0 0 4.56E+07 2.00E+07 - - - 2.1317 0.9521 230117_WJC_METTL3_WT_vs_EV_F03.15359.15359.2 0.00264 16-Aug R.AVFPSIVGR[166.11].P "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 31 954.5526 1.24 21351 15359 2 954.554838 478.2836 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 9.79 3208.6 - 1.40E+06 - - - 2.3226 - 1.717 0.354 - 187 1 1 0 0.0022 9 0 0 0 1.27E+09 1.02E+09 - - - 3.2189 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.15365.15365.2 0.0792 20-Aug R.LVEMASSLAIR.E "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1188.6536 9.34 21355 15365 2 1188.657939 595.3341 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3209.3 - 275777 - - - 3.6133 - 1.736 0.344 - 143.5 1 2 0 0.0043 11 0 0 0 8.17E+06 8.75E+05 - - - 3.0726 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15379.15379.2 0.000922 14-Aug R.GFTLVGMK[136.11].M "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 859.4717 0.96 21361 15379 2 859.474039 430.7431 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.75 3211.2 - 4.13E+06 - - - 2.7098 - 1.953 0.428 - 282.4 1 2 0 0.0023 8 0 0 0 1.01E+09 1.05E+09 - - - 4.2203 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.15380.15380.2 0.223 12-Sep K.TSILVFK[136.11].D sp|Q9BRS2|RIOK1_HUMAN 1 814.5044 0.62 21362 15380 2 814.508032 408.2595 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 8.41 3211.2 - 1.40E+06 - - - 4.4702 - 1.966 0.328 - 357 1 2 0 0.0036 7 0 0 0 4.57E+07 7.35E+07 - - - 3.6044 1 230117_WJC_METTL3_WT_vs_EV_F03.15383.15383.2 5.59E-05 16-Dec K.LGEWVGLC[160.03]K.L sp|P25398|RS12_HUMAN 1 1060.5376 2.19 21364 15383 2 1060.539053 531.2761 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3211.6 - 1.28E+07 - - - 1.4153 - 2.22 0.512 - 573.8 1 2 0 0.0015 9 0 0 0 3.69E+08 1.68E+08 - - - 5.1294 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.15394.15394.2 0.00263 18-Aug K.VLFTGVVDAR.G sp|Q14676|MDC1_HUMAN 1 1075.6026 2.19 21370 15394 2 1075.604366 538.8086 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 5.81 3213 - 1.09E+06 - - - 1.6465 - 1.854 0.35 - 215.2 1 2 0 0.0018 10 0 0 0 4.33E+07 1.98E+07 - - - 3.3487 0.9636 230117_WJC_METTL3_WT_vs_EV_F03.15401.15401.2 2.99 14-Jul K.ILEDSFLK.S sp|Q9Y6X8|ZHX2_HUMAN 1 963.5277 5.88 21374 15401 2 963.527868 482.7711 Zinc fingers and homeoboxes protein 2 OS=Homo sapiens OX=9606 GN=ZHX2 PE=1 SV=1 4.37 3213.9 - 251325 - - - 0.1764 - 1.154 0.044 - 94.1 1 2 0 0.0002 8 0 0 0 2.79E+07 4.75E+06 - - - -0.2021 0.9804 230117_WJC_METTL3_WT_vs_EV_F03.15402.15402.2 0.27 16-Jun R.LLDEYNLVR.S "sp|P46531|NOTC1_HUMAN,tr|A0A7P0T8U6|A0A7P0T8U6_HUMAN,tr|A0A7P0TA56|A0A7P0TA56_HUMAN,tr|A0A7P0TB20|A0A7P0TB20_HUMAN,tr|A0A7P0T8W1|A0A7P0T8W1_HUMAN" 5 1133.6081 2.22 21375 15402 2 1133.611032 567.8113 Neurogenic locus notch homolog protein 1 OS=Homo sapiens OX=9606 GN=NOTCH1 PE=1 SV=4 4.37 3214 - 92969.5 - - - 2.6094 - 1.258 0.076 - 73.9 1 2 0 0.003 9 0 0 0 6.91E+06 3.11E+06 - - - 0.2654 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.15403.15403.2 1.39 22-Nov K.AVASAAAALVLK[136.11].A sp|Q9Y490|TLN1_HUMAN 1 1091.6794 1.4 21376 15403 2 1091.681966 546.847 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.8 3214.1 - 222230 - - - 2.3551 - 1.951 0.333 - 230.5 1 2 0 0.0026 12 0 0 0 4.44E+07 3.17E+07 - - - 3.2583 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15406.15406.2 0.00146 22-Nov K.AVASAAAALVLK.A sp|Q9Y490|TLN1_HUMAN 1 1083.6652 1.14 21377 15406 2 1083.667226 542.8399 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.8 3214.5 - 416713 - - - 1.8742 - 2.236 0.334 - 318.3 1 2 0 0.002 12 0 0 0 3.43E+07 3.02E+07 - - - 3.6246 0.8762 230117_WJC_METTL3_WT_vs_EV_F03.15412.15412.2 22.4 14-Jul K.AGLSVLLK.A "sp|Q969N2|PIGT_HUMAN,tr|A0A1W2PRZ8|A0A1W2PRZ8_HUMAN,tr|H7C2Y2|H7C2Y2_HUMAN,tr|A0A1W2PPR6|A0A1W2PPR6_HUMAN,tr|A0A1W2PPS0|A0A1W2PPS0_HUMAN,tr|A0A1W2PR92|A0A1W2PR92_HUMAN,tr|A0A1W2PPI8|A0A1W2PPI8_HUMAN,tr|A0A1W2PRG1|A0A1W2PRG1_HUMAN,tr|A0A1W2PRV7|A0A1W2PRV7_HUMAN,tr|A0A1W2PQ52|A0A1W2PQ52_HUMAN,tr|A0A1W2PRH2|A0A1W2PRH2_HUMAN,tr|A0A1W2PNP0|A0A1W2PNP0_HUMAN,tr|A0A1W2PNW9|A0A1W2PNW9_HUMAN,tr|A0A1W2PP57|A0A1W2PP57_HUMAN,tr|A0A1W2PPQ7|A0A1W2PPQ7_HUMAN,tr|A0A1W2PQ29|A0A1W2PQ29_HUMAN,tr|A0A1W2PQN1|A0A1W2PQN1_HUMAN,tr|A0A1W2PPC3|A0A1W2PPC3_HUMAN" 18 799.5167 1.17 21382 15412 2 799.518033 400.7656 GPI transamidase component PIG-T OS=Homo sapiens OX=9606 GN=PIGT PE=1 SV=1 8.8 3215.1 - 673603 - - - 1.6172 - 0.964 0.002 - 78 2 2 0 0.0013 8 0 0 0 2.93E+07 2.50E+07 - - - -1.1897 0.996 230117_WJC_METTL3_WT_vs_EV_F03.15413.15413.2 0.117 12-Jul K.LC[160.03]TFILK.N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 893.5045 1.3 21383 15413 2 893.506116 447.7595 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3215.2 - 610211 - - - 1.8523 - 1.24 0.199 - 112 1 2 0 0.0017 7 0 0 0 4.40E+07 3.37E+07 - - - 1.1919 0.9967 230117_WJC_METTL3_WT_vs_EV_F03.15414.15414.2 0.0069 12-Aug K.LC[160.03]TFILK[136.11].N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 901.5187 1.29 21384 15414 2 901.520312 451.7666 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3215.3 - 408038 - - - 1.8314 - 1.358 0.182 - 136.8 1 2 0 0.0017 7 0 0 0 4.19E+07 3.25E+07 - - - 1.3544 0.9352 230117_WJC_METTL3_WT_vs_EV_F03.15439.15439.2 2.25 12-Jun K.DFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 834.46 1.82 21396 15439 2 834.46364 418.2373 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.84 3218.5 - 7.53E+06 - - - 4.4184 - 1.214 0.076 - 97 1 2 0 0.0037 7 0 0 0 1.54E+09 8.50E+08 - - - 0.2156 0.9813 230117_WJC_METTL3_WT_vs_EV_F03.15442.15442.2 0.424 12-Jul R.ALTALFK.E "sp|Q9UBB4|ATX10_HUMAN,tr|A0A1W2PQD2|A0A1W2PQD2_HUMAN" 2 762.464 1.57 21397 15442 2 762.467379 382.2393 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 8.8 3218.9 - 591955 - - - 4.4632 - 1.208 0.206 - 188.7 1 2 0 0.0034 7 0 0 0 5.06E+07 3.23E+07 - - - 1.1602 0.9149 230117_WJC_METTL3_WT_vs_EV_F03.15444.15444.2 2.1 14-May K.VGRPTASK.A sp|Q9H1E3|NUCKS_HUMAN 1 814.4661 0.13 21399 15444 2 814.468778 408.2403 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 OS=Homo sapiens OX=9606 GN=NUCKS1 PE=1 SV=1 11 3219.1 - 1.01E+06 - - - 3.2868 - 1.137 0.066 - 76 7 2 0 0.0027 8 0 0 0 2.94E+08 2.31E+09 - - - -0.4626 0.9954 230117_WJC_METTL3_WT_vs_EV_F03.15448.15448.2 0.631 12-Jul R.FLVTVIK.D "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 818.5266 1.63 21401 15448 2 818.528628 410.2706 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3219.6 - 1.25E+06 - - - 2.5069 - 1.414 0.155 - 166.5 1 2 0 0.0021 7 0 0 0 1.25E+08 7.67E+07 - - - 1.2828 0.996 230117_WJC_METTL3_WT_vs_EV_F03.15455.15455.2 0.15 12-Jul R.ALTALFK[136.11].E "sp|Q9UBB4|ATX10_HUMAN,tr|A0A1W2PQD2|A0A1W2PQD2_HUMAN" 2 770.4782 1.58 21405 15455 2 770.479718 386.2464 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 8.8 3220.6 - 1.21E+06 - - - 2.0014 - 1.261 0.198 - 172.9 1 2 0 0.0015 7 0 0 0 5.12E+07 3.25E+07 - - - 1.2377 0.946 230117_WJC_METTL3_WT_vs_EV_F03.15456.15456.2 0.00184 18-Aug K.LLHHLSDLAL.T "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1130.6448 - 21406 15456 2 1130.647376 566.3297 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3220.7 - 732370 - - - 2.2837 - 1.699 0.339 - 154.4 1 1 0 0.0026 10 0 0 0 - - - - - 3.0235 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.15460.15460.2 0.00464 22-Oct K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.21 21409 15460 2 1287.759097 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3221.1 - 1.07E+06 - - - 0.9583 - 2.04 0.311 - 179.2 1 2 0 0.0012 12 0 0 0 1.03E+08 8.52E+07 - - - 3.2136 0.999 230117_WJC_METTL3_WT_vs_EV_F03.15463.15463.2 0.0132 14-Jul R.LYNYFYDR.R "sp|Q96GD4|AURKB_HUMAN,tr|J3QR41|J3QR41_HUMAN,tr|J3QLN8|J3QLN8_HUMAN,tr|J3KTD6|J3KTD6_HUMAN,tr|J3KT86|J3KT86_HUMAN" 5 1152.524 2.47 21410 15463 2 1152.524315 577.2693 Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3 5.83 3221.5 - 367214 - - - 0.2646 - 1.363 0.364 - 149.3 1 2 0 0.0003 8 0 0 0 9.98E+06 4.04E+06 - - - 2.6634 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15471.15471.2 0.000893 16-Sep R.AATLMMLGR.F "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PR93|A0A6I8PR93_HUMAN,tr|K7ESP1|K7ESP1_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|K7EJE9|K7EJE9_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|K7ELJ8|K7ELJ8_HUMAN,tr|K7EN19|K7EN19_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EJL5|K7EJL5_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|K7EJV7|K7EJV7_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 21 962.5041 0.97 21416 15471 2 962.505938 482.2593 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 9.79 3222.3 - 1.50E+06 - - - 1.8649 - 1.712 0.419 - 238.5 1 2 0 0.0018 9 0 0 0 5.63E+07 5.82E+07 - - - 3.6907 0.9889 230117_WJC_METTL3_WT_vs_EV_F03.15475.15475.2 3.85 12-Jun R.C[160.03]ILPFDK[136.11].E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 899.4666 1.36 21418 15475 2 899.468043 450.7406 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.83 3222.8 - 1.69E+06 - - - 1.5765 - 1.143 0.128 - 163 1 2 0 0.0014 7 0 0 0 1.54E+08 1.13E+08 - - - 0.4095 0.9741 230117_WJC_METTL3_WT_vs_EV_F03.15479.15479.2 1.42 18-Jul R.LGTVLPVIEK[136.11].E sp|O75691|UTP20_HUMAN 1 1075.6732 0.87 21420 15479 2 1075.676052 538.8439 Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3 6 3223.3 - 219849 - - - 2.6077 - 1.161 0.084 - 87.9 1 2 0 0.0028 10 0 0 0 1.01E+07 1.15E+07 - - - 0.0772 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.15480.15480.2 0.00103 20-Oct K.WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1223.643 0.88 21421 15480 2 1223.642484 612.8288 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3223.4 - 187273 - - - -0.429 - 2.04 0.452 - 161 1 2 0 -0.0005 11 0 0 0 4.55E+07 5.19E+07 - - - 4.308 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.15482.15482.2 0.0111 22-Sep K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.2 21422 15482 2 1277.751938 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3223.6 - 458781 - - - 1.8353 - 1.571 0.114 - 141.7 1 2 0 0.0023 12 0 0 0 1.01E+08 8.41E+07 - - - 1.0708 0.995 230117_WJC_METTL3_WT_vs_EV_F03.15486.15486.2 0.0377 12-Jul K.YIQELWR[166.11].K "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1016.5319 0.76 21424 15486 2 1016.529469 509.2732 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 6 3224.1 - 6.44E+06 - - - -2.3777 - 1.404 0.347 - 202.4 1 2 0 -0.0024 7 0 0 0 1.38E+08 1.82E+08 - - - 2.6784 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.15489.15489.2 0.00543 16-Sep R.LIVNVNDLR[166.11].R sp|P25205|MCM3_HUMAN 1 1064.6218 6.2 21425 15489 2 1064.622539 533.3182 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.84 3224.5 - 1.24E+06 - - - 0.728 - 1.68 0.3 - 265.5 1 2 0 0.0008 9 0 0 0 1.41E+08 2.28E+07 - - - 2.7575 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.15494.15494.2 0.532 14-Aug R.GLVVPVIR[166.11].N sp|P36957|ODO2_HUMAN 1 861.5675 0.89 21428 15494 2 861.567594 431.791 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3225.1 - 1.03E+06 - - - 0.0592 - 1.686 0.243 - 353.5 1 2 0 0.0001 8 0 0 0 7.62E+07 8.55E+07 - - - 2.4112 0.9948 230117_WJC_METTL3_WT_vs_EV_F03.15501.15501.2 0.421 14-Jul K.VFPLAEYR.T sp|Q86T24|KAISO_HUMAN 1 993.5284 6.81 21433 15501 2 993.528757 497.7715 Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2 5.97 3225.9 - 898590 - - - 0.3925 - 1.424 0.135 - 219.6 1 2 0 0.0004 8 0 0 0 2.04E+07 2.99E+06 - - - 1.104 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.15504.15504.2 9.62E-05 20-Oct K.WEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1215.6288 0.85 21435 15504 2 1215.631628 608.8217 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3226.2 - 533566 - - - 2.319 - 1.877 0.52 - 206.6 1 2 0 0.0028 11 0 0 0 4.57E+07 5.38E+07 - - - 4.5843 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.15513.15513.2 0.0428 18-Sep K.ALVLTEIGPK.R sp|O14732|IMPA2_HUMAN 1 1039.6277 999 21440 15513 2 1039.629047 520.8211 Inositol monophosphatase 2 OS=Homo sapiens OX=9606 GN=IMPA2 PE=1 SV=1 6.05 3227.3 - 500596 - - - 1.2504 - 1.68 0.331 - 251.2 1 2 0 0.0013 10 0 0 0 9.68E+06 0.00E+00 - - - 2.9335 0.9887 230117_WJC_METTL3_WT_vs_EV_F03.15523.15523.2 0.229 16-Jul K.FVPLLPGNR.S sp|P78527|PRKDC_HUMAN 1 1011.5866 1.03 21446 15523 2 1011.585472 506.8006 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3228.6 - 805783 - - - -1.0666 - 1.253 0.196 - 173.3 1 2 0 -0.0011 9 0 0 0 4.24E+07 4.10E+07 - - - 1.1408 0.9887 230117_WJC_METTL3_WT_vs_EV_F03.15525.15525.2 0.0231 16-Jul K.FVPLLPGNR[166.11].S sp|P78527|PRKDC_HUMAN 1 1021.5948 1.03 21447 15525 2 1021.595907 511.8047 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3228.9 - 869395 - - - 1.063 - 1.329 0.072 - 165.7 1 2 0 0.0011 9 0 0 0 4.30E+07 4.17E+07 - - - 0.3953 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.15527.15527.2 0.259 14-Aug R.LLFGPTVR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 911.5468 0.87 21449 15527 2 911.548007 456.7807 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3229.1 - 2.21E+06 - - - 1.3153 - 1.318 0.183 - 201.3 1 2 0 0.0012 8 0 0 0 5.67E+07 6.55E+07 - - - 1.225 0.9939 230117_WJC_METTL3_WT_vs_EV_F03.15529.15529.2 0.273 14-Aug R.LLPEQLIK[136.11].E "sp|Q92621|NU205_HUMAN,sp|Q8TBZ9|TEX47_HUMAN" 2 960.6099 1.34 21451 15529 2 960.61128 481.3122 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 6 3229.3 - 1.07E+06 - - - 1.4178 - 1.064 0.217 - 127.9 1 2 0 0.0014 8 0 0 0 5.39E+07 4.03E+07 - - - 0.8304 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.15532.15532.2 0.0283 16-Sep K.LLPDTILEK[136.11].L "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1048.626 0.76 21454 15532 2 1048.627496 525.3203 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 4.37 3229.7 - 476553 - - - 1.4629 - 1.48 0.226 - 198.7 1 2 0 0.0015 9 0 0 0 9.58E+07 1.27E+08 - - - 1.844 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.15533.15533.2 0.0365 14-Jun K.FLILNPSK.R "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 930.5539 0.41 21455 15533 2 930.554681 466.2842 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 8.75 3229.8 - 381283 - - - 0.8887 - 1.355 0.353 - 91.1 1 2 0 0.0008 8 0 0 0 1.71E+07 4.13E+07 - - - 2.5642 0.9952 230117_WJC_METTL3_WT_vs_EV_F03.15537.15537.2 0.0965 16-Aug K.LITWSPVC[160.03]R.N "sp|P07203|GPX1_HUMAN,tr|A0A2R8Y6B6|A0A2R8Y6B6_HUMAN" 2 1130.5907 2.3 21457 15537 2 1130.596863 566.3026 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 8.25 3230.3 - 310730 - - - 5.4954 - 1.883 0.322 - 203.6 1 2 0 0.0062 9 0 0 0 1.08E+07 4.71E+06 - - - 3.2483 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.15538.15538.2 0.856 14-Aug R.GLVVPVIR.N sp|P36957|ODO2_HUMAN 1 851.5593 0.89 21458 15538 2 851.56037 426.7869 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3230.4 - 4.49E+06 - - - 1.2882 - 1.651 0.201 - 339.9 1 2 0 0.0011 8 0 0 0 7.62E+07 8.55E+07 - - - 2.0374 0.8905 230117_WJC_METTL3_WT_vs_EV_F03.15539.15539.2 0.249 14-May K.IFSGVFVK[136.11].V "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 903.5309 1.08 21459 15539 2 903.533199 452.7727 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 8.75 3230.4 - 2.04E+06 - - - 2.5002 - 1.111 0.03 - 43.7 13 2 0 0.0023 8 0 0 0 5.70E+07 5.26E+07 - - - -0.9183 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.15542.15542.2 0.00321 16-Aug K.LLPDTILEK.L "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1040.6118 0.76 21462 15542 2 1040.610682 521.3132 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 4.37 3230.7 - 1.13E+06 - - - -1.0379 - 1.573 0.304 - 158.7 1 2 0 -0.0011 9 0 0 0 9.58E+07 1.26E+08 - - - 2.5965 0.9928 230117_WJC_METTL3_WT_vs_EV_F03.15545.15545.2 0.262 20-Jun R.FIDTTLAITSR.F "sp|Q9Y5J9|TIM8B_HUMAN,tr|G3XAN8|G3XAN8_HUMAN" 2 1236.6714 4.49 21465 15545 2 1236.671176 619.343 Mitochondrial import inner membrane translocase subunit Tim8 B OS=Homo sapiens OX=9606 GN=TIMM8B PE=1 SV=1 5.84 3231.1 - 230673 - - - -0.1836 - 1.349 0.183 - 74.3 2 2 0 -0.0002 11 0 0 0 3.07E+06 6.84E+05 - - - 1.0679 0.9949 230117_WJC_METTL3_WT_vs_EV_F03.15548.15548.2 0.223 14-Aug K.YYVLNALK[136.11].H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 990.563 2.37 21466 15548 2 990.564262 496.2888 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.5 3231.4 - 996546 - - - 1.3063 - 1.104 0.219 - 142.8 1 2 0 0.0013 8 0 0 0 1.27E+08 5.34E+07 - - - 0.9565 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.15550.15550.2 0.0198 14-Jun R.YVLSSYLR.C "sp|Q9BRT9|SLD5_HUMAN,tr|E5RH56|E5RH56_HUMAN,tr|E5RFF9|E5RFF9_HUMAN" 3 999.5389 1.24 21468 15550 2 999.542237 500.7767 DNA replication complex GINS protein SLD5 OS=Homo sapiens OX=9606 GN=GINS4 PE=1 SV=1 8.59 3231.7 - 335782 - - - 3.3065 - 1.399 0.298 - 99.6 1 2 0 0.0033 8 0 0 0 4.67E+06 3.78E+06 - - - 2.2536 0.9958 230117_WJC_METTL3_WT_vs_EV_F03.15554.15554.2 0.333 14-Jun R.LLFGPTVR.L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 901.5385 0.6 21470 15554 2 901.540192 451.7765 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3232.2 - 4.70E+06 - - - 1.8346 - 1.211 0.208 - 99 1 2 0 0.0017 8 0 0 0 5.72E+07 9.50E+07 - - - 1.1542 0.9881 230117_WJC_METTL3_WT_vs_EV_F03.15556.15556.2 0.133 14-Jul R.LGDLVWGK.L "sp|Q49A26|GLYR1_HUMAN,sp|Q9UBC3|DNM3B_HUMAN,tr|K7EQB2|K7EQB2_HUMAN,tr|K7ELL0|K7ELL0_HUMAN" 4 886.4913 0.78 21472 15556 2 886.494292 444.2529 Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4 5.84 3232.4 - 1.89E+06 - - - 3.4281 - 1.04 0.246 - 127.4 1 2 0 0.003 8 0 0 0 5.71E+07 7.34E+07 - - - 0.9753 1 230117_WJC_METTL3_WT_vs_EV_F03.15557.15557.2 8.81E-05 16-Aug K.YMTDGMLLR[166.11].E "sp|Q14562|DHX8_HUMAN,sp|O60231|DHX16_HUMAN,sp|O43143|DHX15_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|F5H658|F5H658_HUMAN" 5 1108.5285 1.27 21473 15557 2 1108.530292 555.2715 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 5.84 3232.5 - 391885 - - - 1.6553 - 1.788 0.574 - 195.3 1 2 0 0.0018 9 0 0 0 2.94E+07 2.31E+07 - - - 4.9611 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.15559.15559.2 0.0909 16-Jul K.LITWSPVC[160.03]R[166.11].N "sp|P07203|GPX1_HUMAN,tr|A0A2R8Y6B6|A0A2R8Y6B6_HUMAN" 2 1140.5989 2.23 21475 15559 2 1140.603652 571.3067 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 8.25 3232.8 - 210737 - - - 4.1487 - 1.403 0.34 - 133.7 1 2 0 0.0047 9 0 0 0 1.03E+07 4.63E+06 - - - 2.5304 0.9947 230117_WJC_METTL3_WT_vs_EV_F03.15561.15561.2 0.126 12-Jun M.GVPAFFR.W sp|Q9H0D6|XRN2_HUMAN 1 792.4283 0.85 21476 15561 2 792.430459 397.2214 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 3233 - 3.55E+06 - - - 2.7763 - 1.096 0.266 - 169.9 1 2 0 0.0022 7 0 0 0 1.99E+08 2.34E+08 - - - 1.2954 0.9937 230117_WJC_METTL3_WT_vs_EV_F03.15569.15569.2 0.094 14-Aug K.YYVLNALK.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 982.5488 2.29 21482 15569 2 982.549281 492.2817 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.5 3233.9 - 5.66E+06 - - - 0.5221 - 1.164 0.191 - 155.9 1 2 0 0.0005 8 0 0 0 1.28E+08 5.60E+07 - - - 0.9096 0.9251 230117_WJC_METTL3_WT_vs_EV_F03.15578.15578.2 21.1 12-Jun K.ILTVELR[166.11].T "sp|Q9Y485|DMXL1_HUMAN,tr|F5H269|F5H269_HUMAN" 2 852.5308 1.29 21489 15578 2 852.531413 427.2727 DmX-like protein 1 OS=Homo sapiens OX=9606 GN=DMXL1 PE=1 SV=3 6 3235 - 351105 - - - 0.6921 - 1.096 0 - 72.3 2 2 0 0.0006 7 0 0 0 7.95E+06 6.18E+06 - - - -0.8032 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.15591.15591.2 0.0158 12-Jun M.GVPAFFR[166.11].W sp|Q9H0D6|XRN2_HUMAN 1 802.4365 0.85 21498 15591 2 802.437656 402.2255 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 3236.6 - 1.22E+07 - - - 1.4045 - 1.167 0.309 - 178.8 1 2 0 0.0011 7 0 0 0 2.02E+08 2.36E+08 - - - 1.8123 0.9945 230117_WJC_METTL3_WT_vs_EV_F03.15593.15593.2 0.129 14-Jun R.YLAQYYFK[136.11].C sp|Q9UJX2|CDC23_HUMAN 1 1102.5579 0.75 21500 15593 2 1102.562177 552.2862 Cell division cycle protein 23 homolog OS=Homo sapiens OX=9606 GN=CDC23 PE=1 SV=3 8.43 3236.8 - 413100 - - - 3.8946 - 1.198 0.309 - 75 1 2 0 0.0043 8 0 0 0 6.40E+06 8.52E+06 - - - 1.8668 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.15594.15594.2 0.0169 18-Aug K.LIESAEELIR[166.11].D "sp|Q13217|DNJC3_HUMAN,tr|X6R9L0|X6R9L0_HUMAN" 2 1181.6531 1.79 21501 15594 2 1181.655363 591.8338 DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1 4.25 3237 - 281081 - - - 1.8956 - 1.809 0.339 - 166.4 1 2 0 0.0022 10 0 0 0 1.03E+07 5.72E+06 - - - 3.1988 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.15600.15600.2 0.00426 16-Aug R.LFEGNALLR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1031.5764 0.86 21505 15600 2 1031.580741 516.7955 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3237.7 - 1.68E+06 - - - 4.2275 - 1.762 0.412 - 219.5 1 2 0 0.0044 9 0 0 0 1.06E+09 1.23E+09 - - - 3.7214 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.15601.15601.2 0.0103 16-Sep R.VLGMTLIQK[136.11].C sp|Q04760|LGUL_HUMAN 1 1009.6085 1.27 21506 15601 2 1009.61241 505.8115 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3237.7 - 967499 - - - 3.8351 - 1.654 0.276 - 187.2 1 2 0 0.0039 9 0 0 0 3.14E+07 2.48E+07 - - - 2.5341 0.9421 230117_WJC_METTL3_WT_vs_EV_F03.15605.15605.2 0.08 16-Jul R.AIEQLAAMD.- "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 3 960.4586 - 21510 15605 2 960.459306 481.2366 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.03 3238.2 - 229060 - - - 0.7007 - 1.139 0.011 - 100.6 2 2 0 0.0007 9 0 0 0 - - - - - -0.6359 0.9957 230117_WJC_METTL3_WT_vs_EV_F03.15606.15606.2 0.197 14-Sep K.MLLSLPEK.V "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 929.5256 1.04 21511 15606 2 929.529168 465.7701 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 5.75 3238.3 - 173022 - - - 3.8493 - 1.591 0.221 - 258.6 1 2 0 0.0036 8 0 0 0 1.58E+07 1.52E+07 - - - 2.0727 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.15607.15607.2 7.69E-05 18-Sep K.LLANMVYQYK[136.11].G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1249.662 1.87 21512 15607 2 1249.658296 625.8383 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3238.4 - 151571 - - - -2.988 - 1.735 0.488 - 260.4 1 2 0 -0.0037 10 0 0 0 2.47E+07 1.32E+07 - - - 4.1822 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15612.15612.2 0.00138 16-Aug R.LFEGNALLR[166.11].R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1041.5847 0.86 21515 15612 2 1041.585426 521.7996 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3239 - 3.96E+06 - - - 0.745 - 1.724 0.422 - 173.2 1 2 0 0.0008 9 0 0 0 1.06E+09 1.23E+09 - - - 3.7333 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.15614.15614.2 0.000175 14-Sep K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 1.75 21517 15614 2 895.483363 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3239.1 - 1.57E+06 - - - 3.3602 - 1.74 0.409 - 193.8 1 2 0 0.003 8 0 0 0 2.98E+09 1.70E+09 - - - 3.7314 1 230117_WJC_METTL3_WT_vs_EV_F03.15619.15619.2 0.000884 18-Nov K.LLANMVYQYK.G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1241.6478 1.87 21522 15619 2 1241.648311 621.8312 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3239.5 - 338322 - - - 0.3874 - 2.191 0.476 - 387.3 1 2 0 0.0005 10 0 0 0 2.47E+07 1.32E+07 - - - 4.746 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.15627.15627.2 0.104 14-Aug K.MLLSLPEK[136.11].V "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 937.5398 1.04 21528 15627 2 937.542519 469.7772 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 5.75 3240.3 - 878064 - - - 2.9108 - 1.701 0.294 - 259.3 1 2 0 0.0027 8 0 0 0 1.55E+07 1.49E+07 - - - 2.8138 0.995 230117_WJC_METTL3_WT_vs_EV_F03.15629.15629.2 0.00321 20-Oct R.VIGTLLGTVDK.H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1114.6598 1.14 21530 15629 2 1114.665191 558.3372 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3240.5 - 584826 - - - 4.8589 - 1.632 0.31 - 192.2 1 2 0 0.0054 11 0 0 0 8.72E+07 7.66E+07 - - - 2.654 0.9078 230117_WJC_METTL3_WT_vs_EV_F03.15633.15633.2 2.9 16-Jun R.FLPSPVVIK[136.11].K "sp|Q13618|CUL3_HUMAN,tr|H7C399|H7C399_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 3 1006.6307 0.6 21532 15633 2 1006.633394 504.3226 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 8.75 3241 - 2.43E+06 - - - 2.722 - 1.07 0.005 - 106 1 2 0 0.0027 9 0 0 0 4.62E+07 7.69E+07 - - - -0.7272 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.15634.15634.2 0.000452 20-Sep R.VIGTLLGTVDK[136.11].H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1122.674 1.14 21533 15634 2 1122.677011 562.3443 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3241.1 - 610576 - - - 2.7043 - 1.926 0.401 - 186.1 1 2 0 0.003 11 0 0 0 8.72E+07 7.66E+07 - - - 3.775 0.8752 230117_WJC_METTL3_WT_vs_EV_F03.15636.15636.2 0.327 12-Jul L.FGDLLLK[136.11].Q "sp|Q15147|PLCB4_HUMAN,sp|Q6P2Q9|PRP8_HUMAN,tr|A0A7P0MRI8|A0A7P0MRI8_HUMAN" 3 812.4887 1.31 21535 15636 2 812.489507 407.2516 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4 PE=1 SV=3" 5.84 3241.3 - 962135 - - - 0.9428 - 1.518 0.201 - 114.4 1 1 0 0.0008 7 0 0 0 1.65E+08 1.26E+08 - - - 1.8479 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.15638.15638.2 0.0272 14-Sep R.IAVPVLVR.D sp|P52952|NKX25_HUMAN 1 865.5749 1.98 21537 15638 2 865.576039 433.7947 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 9.75 3241.5 - 489827 - - - 1.2893 - 1.686 0.315 - 309.9 1 2 0 0.0011 8 0 0 0 2.27E+07 1.15E+07 - - - 2.9427 0.9459 230117_WJC_METTL3_WT_vs_EV_F03.15640.15640.2 2.52 12-May R.GFFNGLR[166.11].T "sp|Q9Y394|DHRS7_HUMAN,tr|H0YJ66|H0YJ66_HUMAN,tr|H0YJE4|H0YJE4_HUMAN,tr|H0YJR8|H0YJR8_HUMAN" 4 819.4267 1.29 21539 15640 2 819.429951 410.7206 Dehydrogenase\reductase SDR family member 7 OS=Homo sapiens OX=9606 GN=DHRS7 PE=1 SV=1 9.75 3241.7 - 213094 - - - 3.976 - 1.126 0.098 - 71 1 2 0 0.0033 7 0 0 0 9.25E+06 7.18E+06 - - - 0.1398 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.15644.15644.2 0.0406 16-Jul R.FLPSPVVIK.K "sp|Q13618|CUL3_HUMAN,tr|H7C399|H7C399_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 3 998.6165 0.6 21541 15644 2 998.618249 500.3155 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 8.75 3242.3 - 1.23E+06 - - - 1.7975 - 1.216 0.278 - 139 1 2 0 0.0018 9 0 0 0 4.62E+07 7.64E+07 - - - 1.6595 0.9853 230117_WJC_METTL3_WT_vs_EV_F03.15649.15649.2 4.1 14-Oct R.IAVPVLVR[166.11].D sp|P52952|NKX25_HUMAN 1 875.5832 2.21 21544 15649 2 875.584565 438.7989 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 9.75 3242.9 - 342111 - - - 1.567 - 1.395 0.023 - 412.1 1 2 0 0.0014 8 0 0 0 2.54E+07 1.15E+07 - - - 0.2144 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.15650.15650.2 0.111 18-Aug R.IVLVDDSIVR.G sp|Q06203|PUR1_HUMAN 1 1127.655 2 21545 15650 2 1127.656214 564.8348 Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1 4.21 3243 - 363503 - - - 1.0553 - 1.718 0.191 - 164.7 1 2 0 0.0012 10 0 0 0 3.69E+07 1.84E+07 - - - 1.9619 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.15652.15652.2 5.75E-05 26-Aug K.VLEQLTGQTPVFSK[136.11].A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1553.8545 1.33 21547 15652 2 1553.863103 777.9345 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3243.2 - 133337 - - - 5.5629 - 1.905 0.515 - 158.5 1 2 0 0.0086 14 0 0 0 4.03E+06 3.02E+06 - - - 4.4594 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15655.15655.2 0.0017 14-Sep K.FVADGIFK[136.11].A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 903.4946 1.75 21548 15655 2 903.496222 452.7546 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3243.6 - 5.48E+07 - - - 1.8462 - 1.737 0.417 - 208.3 1 2 0 0.0017 8 0 0 0 2.98E+09 1.70E+09 - - - 3.7857 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.15656.15656.2 0.126 14-Aug K.VFNLGVYR[166.11].R "sp|O60825|F262_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN" 2 976.537 0.55 21549 15656 2 976.538426 489.2758 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 8.72 3243.7 - 1.89E+06 - - - 1.49 - 1.668 0.151 - 245.4 1 2 0 0.0015 8 0 0 0 3.01E+07 5.45E+07 - - - 1.6989 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.15657.15657.2 0.0209 14-Aug R.FVDGLTFK.V "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 925.4909 0.91 21550 15657 2 925.491892 463.7527 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.84 3243.8 - 1.21E+06 - - - 1.0513 - 1.369 0.338 - 155.8 1 2 0 0.001 8 0 0 0 1.51E+07 1.66E+07 - - - 2.4844 0.9955 230117_WJC_METTL3_WT_vs_EV_F03.15660.15660.2 0.541 14-Aug K.NLYIISVK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 956.5786 1.29 21553 15660 2 956.580949 479.2966 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3244.1 - 509273 - - - 2.4368 - 1.528 0.131 - 171.1 1 2 0 0.0023 8 0 0 0 2.84E+09 2.20E+09 - - - 1.2865 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.15661.15661.2 0.0234 18-Jul R.LIYTAGGYFR.Q sp|Q14145|KEAP1_HUMAN 1 1159.6026 2.48 21554 15661 2 1159.604515 580.8086 Kelch-like ECH-associated protein 1 OS=Homo sapiens OX=9606 GN=KEAP1 PE=1 SV=2 8.59 3244.3 - 440909 - - - 1.6557 - 1.16 0.381 - 122 1 2 0 0.0019 10 0 0 0 8.54E+06 3.45E+06 - - - 2.2687 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.15662.15662.2 0.00187 18-Aug R.IVLVDDSIVR[166.11].G sp|Q06203|PUR1_HUMAN 1 1137.6633 1.98 21555 15662 2 1137.664312 569.8389 Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1 4.21 3244.4 - 342156 - - - 0.8948 - 1.594 0.371 - 150.3 1 2 0 0.001 10 0 0 0 3.64E+07 1.84E+07 - - - 3.0823 1 230117_WJC_METTL3_WT_vs_EV_F03.15663.15663.2 1.04E-05 20-Dec R.LFSGDVVLTAR.D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1176.6503 1 21556 15663 2 1176.650442 589.3324 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3244.5 - 198945 - - - 0.1436 - 2.267 0.532 - 448.1 1 2 0 0.0002 11 0 0 0 1.84E+08 1.85E+08 - - - 5.1844 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.15665.15665.2 0.00251 14-Aug K.VFNLGVYR.R "sp|O60825|F262_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN" 2 966.5287 0.55 21557 15665 2 966.531574 484.2716 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 8.72 3244.7 - 1.07E+06 - - - 2.9725 - 1.665 0.326 - 214 1 2 0 0.0029 8 0 0 0 3.00E+07 5.45E+07 - - - 2.9855 0.9344 230117_WJC_METTL3_WT_vs_EV_F03.15667.15667.2 0.274 12-Sep L.FGDLLLK.Q "sp|Q15147|PLCB4_HUMAN,sp|Q6P2Q9|PRP8_HUMAN,tr|A0A7P0MRI8|A0A7P0MRI8_HUMAN" 3 804.4745 1.31 21558 15667 2 804.475128 403.2445 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4 PE=1 SV=3" 5.84 3245 - 3.36E+06 - - - 0.7297 - 1.874 0.214 - 209.3 1 1 0 0.0006 7 0 0 0 1.65E+08 1.26E+08 - - - 2.6115 1 230117_WJC_METTL3_WT_vs_EV_F03.15672.15672.2 3.29E-05 20-Oct R.LFSGDVVLTAR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1186.6585 1 21563 15672 2 1186.660762 594.3365 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3245.5 - 487135 - - - 1.87 - 2.13 0.503 - 290.6 1 2 0 0.0022 11 0 0 0 1.84E+08 1.85E+08 - - - 4.8009 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.15675.15675.2 0.00607 16-Sep R.LWGEPVNLR.E "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 1082.5873 1.48 21566 15675 2 1082.589783 542.3009 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 6 3245.8 - 299483 - - - 2.313 - 1.885 0.131 - 234.2 1 2 0 0.0025 9 0 0 0 1.28E+07 8.61E+06 - - - 1.8418 0.9849 230117_WJC_METTL3_WT_vs_EV_F03.15676.15676.2 0.339 18-Jun R.LIYTAGGYFR[166.11].Q sp|Q14145|KEAP1_HUMAN 1 1169.6109 2.48 21567 15676 2 1169.614669 585.8127 Kelch-like ECH-associated protein 1 OS=Homo sapiens OX=9606 GN=KEAP1 PE=1 SV=2 8.59 3246 - 187274 - - - 3.2524 - 1.123 0.183 - 68.9 1 2 0 0.0038 10 0 0 0 8.54E+06 3.45E+06 - - - 0.7152 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.15679.15679.2 0.00431 14-Aug K.NLYIISVK.G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 948.5644 1.29 21568 15679 2 948.565142 475.2895 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3246.4 - 3.05E+06 - - - 0.7633 - 1.419 0.257 - 224.7 1 2 0 0.0007 8 0 0 0 2.84E+09 2.20E+09 - - - 1.9944 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.15681.15681.2 0.114 14-Jul R.LLPSLIGR[166.11].H "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 4 877.5625 0.75 21570 15681 2 877.564107 439.7885 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 9.75 3246.6 - 778682 - - - 1.8791 - 1.464 0.259 - 193.7 1 2 0 0.0016 8 0 0 0 5.83E+07 7.80E+07 - - - 2.1031 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.15682.15682.2 0.319 14-Jun R.LLPSLIGR.H "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 4 867.5542 0.75 21571 15682 2 867.55443 434.7844 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 9.75 3246.7 - 984579 - - - 0.2789 - 1.249 0.286 - 114.9 1 2 0 0.0002 8 0 0 0 5.83E+07 7.80E+07 - - - 1.8239 0.994 230117_WJC_METTL3_WT_vs_EV_F03.15683.15683.2 0.245 16-Aug K.EALEAVLIK[136.11].G "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 992.5997 1.47 21572 15683 2 992.603817 497.3072 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 4.53 3246.9 - 221607 - - - 4.0993 - 1.455 0.244 - 139 1 2 0 0.0041 9 0 0 0 1.88E+07 1.29E+07 - - - 1.9268 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.15686.15686.2 0.0129 14-Aug R.LFC[160.03]VGFTK.K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 970.4946 0.83 21573 15686 2 970.49645 486.2546 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.22 3247.3 - 1.03E+06 - - - 1.8815 - 1.672 0.377 - 162.5 1 2 0 0.0018 8 0 0 0 3.36E+08 4.06E+08 - - - 3.3752 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.15690.15690.2 1.06 14-Aug K.TAVLTLIR.E "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 8 885.5648 1.3 21576 15690 2 885.566881 443.7897 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 9.41 3247.6 - 1.68E+06 - - - 2.403 - 1.636 0.123 - 281.4 1 2 0 0.0021 8 0 0 0 1.25E+08 9.57E+07 - - - 1.4334 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.15691.15691.2 0.00216 22-Oct R.VLVTGATGLLGR.A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1155.6976 1.55 21577 15691 2 1155.69911 578.8561 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3247.8 - 694097 - - - 1.3429 - 1.853 0.478 - 220.5 1 2 0 0.0016 12 0 0 0 2.09E+07 1.35E+07 - - - 4.1939 0.9869 230117_WJC_METTL3_WT_vs_EV_F03.15693.15693.2 0.593 14-Jun K.ILIDSIYK.V "sp|Q4KWH8|PLCH1_HUMAN,tr|A0A2U3TZV8|A0A2U3TZV8_HUMAN" 2 963.5641 1.63 21579 15693 2 963.563573 482.7893 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 OS=Homo sapiens OX=9606 GN=PLCH1 PE=1 SV=1" 5.83 3248 - 346849 - - - -0.5303 - 1.186 0.165 - 65.7 1 2 0 -0.0005 8 0 0 0 4.27E+06 2.62E+06 - - - 0.774 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.15706.15706.2 0.0644 14-Aug R.TVETLLLR.F "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 6 943.5702 0.56 21586 15706 2 943.571618 472.7924 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 5.66 3249.6 - 986867 - - - 1.4689 - 1.601 0.181 - 185.1 1 2 0 0.0014 8 0 0 0 8.04E+07 1.44E+08 - - - 1.7968 0.9952 230117_WJC_METTL3_WT_vs_EV_F03.15707.15707.2 0.263 18-Jun R.LVPLQEEIYR.K "sp|Q2NKX8|ERC6L_HUMAN,tr|B5MDQ0|B5MDQ0_HUMAN" 2 1258.6921 3.47 21587 15707 2 1258.692036 630.3533 DNA excision repair protein ERCC-6-like OS=Homo sapiens OX=9606 GN=ERCC6L PE=1 SV=1 4.53 3249.7 - 196175 - - - -0.081 - 1.268 0.222 - 163.9 1 2 0 -0.0001 10 0 0 0 7.08E+06 2.04E+06 - - - 1.3434 0.9844 230117_WJC_METTL3_WT_vs_EV_F03.15718.15718.2 0.302 14-Jun K.AVIELLEK[136.11].S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|H0Y327|H0Y327_HUMAN,tr|Q5JYA8|Q5JYA8_HUMAN,tr|Q5JYA3|Q5JYA3_HUMAN" 6 921.5626 2.63 21594 15718 2 921.563058 461.7886 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.53 3251.1 - 827516 - - - 0.4601 - 1.533 0.03 - 86.2 4 2 0 0.0004 8 0 0 0 4.72E+07 1.80E+07 - - - 0.282 1 230117_WJC_METTL3_WT_vs_EV_F03.15719.15719.2 0.00289 22-Nov R.VLVTGATGLLGR[166.11].A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1165.7058 1.55 21595 15719 2 1165.706523 583.8602 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3251.2 - 919149 - - - 0.5962 - 2.089 0.504 - 348.3 1 2 0 0.0007 12 0 0 0 2.09E+07 1.35E+07 - - - 4.7017 0.9837 230117_WJC_METTL3_WT_vs_EV_F03.15720.15720.2 0.0667 16-Aug K.LIPPQDILR[166.11].D sp|Q96A65|EXOC4_HUMAN 1 1073.6472 1.7 21596 15720 2 1073.65278 537.8309 Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1 5.84 3251.4 - 343870 - - - 5.1507 - 1.293 0.255 - 148 1 2 0 0.0055 9 0 0 0 2.06E+07 1.21E+07 - - - 1.6661 0.9844 230117_WJC_METTL3_WT_vs_EV_F03.15724.15724.2 0.0415 16-Aug R.FFMGNQVLK.V sp|P13010|XRCC5_HUMAN 1 1082.5583 0.84 21598 15724 2 1082.554475 542.2864 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3251.9 - 148280 - - - -3.5213 - 1.356 0.31 - 131.9 1 2 0 -0.0038 9 0 0 0 5.64E+07 6.75E+07 - - - 2.2105 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.15727.15727.2 0.0231 16-Jul R.FFMGNQVLK[136.11].V sp|P13010|XRCC5_HUMAN 1 1090.5725 0.84 21601 15727 2 1090.573766 546.2935 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3252.1 - 456566 - - - 1.1728 - 1.379 0.273 - 95.4 1 2 0 0.0013 9 0 0 0 5.64E+07 6.74E+07 - - - 1.9867 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.15732.15732.2 0.376 12-Aug R.LSAILFK.L "sp|Q9NSV4|DIAP3_HUMAN,sp|Q12830|BPTF_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|J3KSK9|J3KSK9_HUMAN,tr|J3QQQ8|J3QQQ8_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN" 7 790.4953 1.46 21604 15732 2 790.496378 396.2549 Protein diaphanous homolog 3 OS=Homo sapiens OX=9606 GN=DIAPH3 PE=1 SV=4 8.75 3252.8 - 483194 - - - 1.3941 - 1.674 0.127 - 161.6 1 2 0 0.0011 7 0 0 0 1.16E+07 7.99E+06 - - - 1.6112 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.15735.15735.2 0.00588 14-Jul R.ELYPVEFR.N "sp|Q5BJF2|SGMR2_HUMAN,tr|J3KT68|J3KT68_HUMAN" 2 1051.5338 1.19 21607 15735 2 1051.534423 526.7742 Sigma intracellular receptor 2 OS=Homo sapiens OX=9606 GN=TMEM97 PE=1 SV=1 4.53 3253 - 801117 - - - 0.5487 - 1.46 0.426 - 219.1 1 2 0 0.0006 8 0 0 0 1.89E+07 1.59E+07 - - - 3.3286 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.15742.15742.2 1.54 14-Jul K.EMVELPLR.H "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN" 10 985.5267 0.75 21612 15742 2 985.52663 493.7706 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.53 3253.9 - 677557 - - - -0.0233 - 1.376 0.218 - 103.5 1 2 0 0 8 0 0 0 1.44E+07 1.93E+07 - - - 1.6138 0.856 230117_WJC_METTL3_WT_vs_EV_F03.15747.15747.2 1.46 16-Apr K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 8.46 21615 15747 2 1014.539752 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3254.6 - 1.03E+06 - - - 5.1028 - 1.048 0.155 - 34.4 7 2 0 0.0052 9 0 0 0 7.05E+07 8.33E+06 - - - -0.0577 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.15748.15748.2 0.000855 18-Sep R.GLIENPALLR[166.11].W sp|O95168|NDUB4_HUMAN 1 1104.6531 1.31 21616 15748 2 1104.654701 553.3338 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3 6 3254.7 - 515467 - - - 1.4819 - 1.992 0.296 - 210.6 1 2 0 0.0016 10 0 0 0 4.64E+07 3.55E+07 - - - 3.1503 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.15749.15749.2 0.112 16-Aug R.ILPQDVILK[136.11].F "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1045.6627 0.96 21617 15749 2 1045.66342 523.8386 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.84 3254.8 - 768298 - - - 0.7058 - 1.412 0.231 - 140.6 1 2 0 0.0007 9 0 0 0 3.74E+07 3.88E+07 - - - 1.7451 0.9956 230117_WJC_METTL3_WT_vs_EV_F03.15755.15755.2 0.0769 14-Jun R.ELYPVEFR[166.11].N "sp|Q5BJF2|SGMR2_HUMAN,tr|J3KT68|J3KT68_HUMAN" 2 1061.5421 1.19 21621 15755 2 1061.543926 531.7783 Sigma intracellular receptor 2 OS=Homo sapiens OX=9606 GN=TMEM97 PE=1 SV=1 4.53 3255.5 - 1.20E+06 - - - 1.7051 - 1.231 0.194 - 121.5 1 2 0 0.0018 8 0 0 0 1.89E+07 1.59E+07 - - - 1.1001 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.15764.15764.2 0.369 14-Jun K.EMVELPLR[166.11].H "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN" 10 995.5349 0.75 21626 15764 2 995.536404 498.7747 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.53 3256.6 - 830119 - - - 1.4876 - 1.359 0.176 - 131.1 1 2 0 0.0015 8 0 0 0 1.46E+07 1.96E+07 - - - 1.2656 0.9942 230117_WJC_METTL3_WT_vs_EV_F03.15766.15766.2 0.0264 16-Sep R.ILPQDVILK.F "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1037.6485 0.95 21628 15766 2 1037.650743 519.8315 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.84 3256.8 - 857137 - - - 2.179 - 1.399 0.132 - 196 1 2 0 0.0023 9 0 0 0 3.61E+07 3.80E+07 - - - 0.9866 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.15767.15767.3 0.00509 Sep-36 R.ILIAK[136.11]PIMFR[166.11].G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1218.7641 1.07 21629 15767 3 1218.769394 407.262 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3256.9 - 749806 - - - 4.3101 - 1.716 0.308 - 65.8 1 2 0 0.0053 10 0 0 0 1.05E+07 9.81E+06 - - - 3.5495 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.15768.15768.2 0.0108 22-Aug K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.21 21630 15768 2 1277.750927 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3257 - 513966 - - - 1.044 - 1.506 0.3 - 131.2 1 2 0 0.0013 12 0 0 0 1.99E+07 1.65E+07 - - - 2.3337 0.991 230117_WJC_METTL3_WT_vs_EV_F03.15773.15773.2 0.474 12-Jul K.SIELFYK[136.11].F sp|P78527|PRKDC_HUMAN 1 906.4942 0.42 21633 15773 2 906.495496 454.2544 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.72 3257.6 - 1.61E+06 - - - 1.4076 - 1.12 0.155 - 168.7 1 2 0 0.0013 7 0 0 0 2.76E+07 6.53E+07 - - - 0.5445 1 230117_WJC_METTL3_WT_vs_EV_F03.15774.15774.3 1.00E-09 22/64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 17.56 21634 15774 3 1786.987375 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3257.8 - 1.29E+06 - - - 2.5042 - 4.093 0.454 - 506.9 1 2 0 0.0045 17 0 0 0 5.03E+07 2.86E+06 - - - 7.1607 0.9945 230117_WJC_METTL3_WT_vs_EV_F03.15781.15781.2 0.324 12-Jun R.VLAAFLR.R "sp|Q9HB09|B2L12_HUMAN,sp|Q99607|ELF4_HUMAN,tr|M0R1Z8|M0R1Z8_HUMAN,tr|A0A087WU18|A0A087WU18_HUMAN,tr|I6LJZ9|I6LJZ9_HUMAN,tr|A0A087WSV0|A0A087WSV0_HUMAN,tr|I6LK00|I6LK00_HUMAN,tr|I6LJZ7|I6LJZ7_HUMAN,tr|M0R1K0|M0R1K0_HUMAN,tr|M0QZM6|M0QZM6_HUMAN" 10 788.4909 2.23 21639 15781 2 788.492305 395.2527 Bcl-2-like protein 12 OS=Homo sapiens OX=9606 GN=BCL2L12 PE=1 SV=1 9.72 3258.6 - 1.36E+06 - - - 1.8339 - 1.38 0.12 - 111.6 1 2 0 0.0014 7 0 0 0 3.09E+07 1.38E+07 - - - 0.9474 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.15785.15785.2 0.00116 18-Nov K.VPVLISPTLK[136.11].H sp|P42684|ABL2_HUMAN 1 1073.694 2.73 21643 15785 2 1073.691944 537.8543 Tyrosine-protein kinase ABL2 OS=Homo sapiens OX=9606 GN=ABL2 PE=1 SV=1 8.72 3259.1 - 488128 - - - -1.8981 - 1.689 0.441 - 298.5 1 2 0 -0.002 10 0 0 0 1.39E+07 5.10E+06 - - - 3.7606 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.15787.15787.2 3.58E-06 20-Oct K.FSPAGPVLSIR[166.11].V "sp|Q13310|PABP4_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN" 4 1152.6531 1.37 21645 15787 2 1152.655618 577.3338 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.75 3259.3 - 320261 - - - 2.2158 - 1.798 0.523 - 237.1 1 2 0 0.0026 11 0 0 0 9.69E+06 7.07E+06 - - - 4.4902 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.15789.15789.3 0.0134 Oct-64 R.IINEPTAAAIAYGLDK[136.11]K[136.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1803.0113 17.56 21647 15789 3 1803.020339 602.011 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3259.5 - 209892 - - - 5.0133 - 2.176 0.308 - 58.4 1 2 0 0.009 17 0 0 0 5.03E+07 2.86E+06 - - - 3.9356 0.9731 230117_WJC_METTL3_WT_vs_EV_F03.15792.15792.2 1.15 12-May K.AFLFVNK.G sp|Q8N0X7|SPART_HUMAN 1 837.4749 1.41 21648 15792 2 837.477148 419.7447 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3259.9 - 1.14E+07 - - - 2.7141 - 1.048 0.122 - 124.5 1 2 0 0.0023 7 0 0 0 1.59E+08 1.12E+08 - - - 0.0899 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.15793.15793.2 0.042 16-Sep R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 0.75 21649 15793 2 960.61226 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3260 - 2.19E+07 - - - 2.438 - 1.452 0.272 - 239.2 1 2 0 0.0023 9 0 0 0 1.18E+10 1.57E+10 - - - 2.1282 0.9862 230117_WJC_METTL3_WT_vs_EV_F03.15794.15794.2 1.31 14-May R.VILLDVAR.G sp|Q9H2M9|RBGPR_HUMAN 1 897.5648 1.19 21650 15794 2 897.566645 449.7897 Rab3 GTPase-activating protein non-catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP2 PE=1 SV=1 5.81 3260 - 2.14E+06 - - - 2.1079 - 1.091 0.141 - 57.7 1 2 0 0.0019 8 0 0 0 1.53E+07 1.29E+07 - - - 0.3445 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15796.15796.2 0.00133 18-Aug K.VPVLISPTLK.H sp|P42684|ABL2_HUMAN 1 1065.6798 2.73 21652 15796 2 1065.681044 533.8472 Tyrosine-protein kinase ABL2 OS=Homo sapiens OX=9606 GN=ABL2 PE=1 SV=1 8.72 3260.2 - 1.71E+06 - - - 1.1842 - 1.519 0.446 - 173.2 1 2 0 0.0013 10 0 0 0 1.39E+07 5.10E+06 - - - 3.5017 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15798.15798.2 0.000295 20-Oct K.FSPAGPVLSIR.V "sp|Q13310|PABP4_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN" 4 1142.6448 1.09 21654 15798 2 1142.645718 572.3297 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.75 3260.4 - 969714 - - - 0.8087 - 1.846 0.404 - 333.7 1 2 0 0.0009 11 0 0 0 9.69E+06 8.85E+06 - - - 3.683 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.15803.15803.2 0.196 16-Sep R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 0.75 21657 15803 2 952.596862 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3261.1 - 1.21E+07 - - - 1.2009 - 1.534 0.151 - 246.4 1 2 0 0.0011 9 0 0 0 1.18E+10 1.57E+10 - - - 1.3938 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.15804.15804.2 0.0593 12-Jun K.AFLFVNK[136.11].G sp|Q8N0X7|SPART_HUMAN 1 845.4891 1.41 21658 15804 2 845.489937 423.7518 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3261.2 - 3.19E+06 - - - 1.0195 - 1.218 0.273 - 162 1 2 0 0.0009 7 0 0 0 1.60E+08 1.13E+08 - - - 1.682 0.936 230117_WJC_METTL3_WT_vs_EV_F03.15806.15806.2 0.0297 18-Oct H.ILSPWGAEVK[136.11].A "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1106.6215 0.96 21660 15806 2 1106.621029 554.318 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3261.3 - 1.90E+06 - - - -0.4672 - 2.021 0.324 - 234.6 1 1 0 -0.0005 10 0 0 0 6.37E+07 6.62E+07 - - - 3.3978 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.15813.15813.2 0.0731 18-Aug R.LGFVAGVINR[166.11].E "sp|Q93050|VPP1_HUMAN,tr|K7EN36|K7EN36_HUMAN,tr|K7EPG4|K7EPG4_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 5 1054.6163 2.53 21667 15813 2 1054.620014 528.3154 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 9.75 3262 - 359911 - - - 3.5368 - 1.767 0.271 - 181.5 1 2 0 0.0037 10 0 0 0 3.37E+07 1.33E+07 - - - 2.6305 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.15818.15818.2 0.00101 18-Oct K.IGDLGLATLK.R "sp|Q9H4A3|WNK1_HUMAN,sp|Q96J92|WNK4_HUMAN,sp|Q9Y3S1|WNK2_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A6PVV2|A6PVV2_HUMAN,tr|K7ENT7|K7ENT7_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 9 999.5964 1.97 21670 15818 2 999.599223 500.8055 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 5.84 3262.5 - 3.64E+06 - - - 2.7771 - 2.013 0.42 - 203.3 1 2 0 0.0028 10 0 0 0 8.70E+07 4.41E+07 - - - 4.0951 0.999 230117_WJC_METTL3_WT_vs_EV_F03.15820.15820.2 0.00867 14-Sep K.YFEYIMAK.E sp|P13674|P4HA1_HUMAN 1 1063.5049 2.82 21672 15820 2 1063.503992 532.7597 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3262.7 - 1.70E+06 - - - -0.8105 - 1.643 0.412 - 237.3 1 2 0 -0.0009 8 0 0 0 4.39E+07 1.56E+07 - - - 3.5813 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15822.15822.2 0.000171 14-Sep K.YFEYIMAK[136.11].E sp|P13674|P4HA1_HUMAN 1 1071.5191 2.82 21674 15822 2 1071.519932 536.7668 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3262.9 - 871804 - - - 0.8194 - 1.586 0.467 - 233.3 1 2 0 0.0009 8 0 0 0 4.39E+07 1.56E+07 - - - 3.881 0.995 230117_WJC_METTL3_WT_vs_EV_F03.15835.15835.2 0.0195 18-Sep K.AFADSSYLLR.H "sp|Q9H5H4|ZN768_HUMAN,tr|H3BS42|H3BS42_HUMAN" 2 1141.5768 1 21685 15835 2 1141.575377 571.7957 Zinc finger protein 768 OS=Homo sapiens OX=9606 GN=ZNF768 PE=1 SV=2 5.88 3264.5 - 510568 - - - -1.2237 - 1.305 0.289 - 212.5 1 2 0 -0.0014 10 0 0 0 1.36E+07 1.36E+07 - - - 1.9182 0.9962 230117_WJC_METTL3_WT_vs_EV_F03.15836.15836.2 0.0209 14-Sep K.GIAYIEFK.T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 939.5066 0.81 21686 15836 2 939.506977 470.7606 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3264.6 - 336752 - - - 0.4343 - 1.756 0.079 - 269.8 1 2 0 0.0004 8 0 0 0 6.26E+08 7.77E+08 - - - 1.3225 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15841.15841.2 0.00134 12-Aug K.QC[160.03]FLVLR.Q "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|H7C278|H7C278_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 5 934.5059 0.5 21689 15841 2 934.506969 468.2602 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 8.25 3265.2 - 2.15E+06 - - - 1.1889 - 1.595 0.411 - 374.7 1 2 0 0.0011 7 0 0 0 2.37E+07 4.75E+07 - - - 3.5556 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.15843.15843.2 9.14E-05 16-Sep K.VLPVGVLYK.V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 986.6165 0.53 21691 15843 2 986.615636 494.3155 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3265.4 - 2.02E+06 - - - -0.8291 - 1.698 0.494 - 224.4 1 2 0 -0.0008 9 0 0 0 1.21E+08 2.28E+08 - - - 4.2212 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.15847.15847.2 0.00338 18-Oct K.AFADSSYLLR[166.11].H "sp|Q9H5H4|ZN768_HUMAN,tr|H3BS42|H3BS42_HUMAN" 2 1151.585 0.99 21695 15847 2 1151.583339 576.7998 Zinc finger protein 768 OS=Homo sapiens OX=9606 GN=ZNF768 PE=1 SV=2 5.88 3265.9 - 799336 - - - -1.4806 - 1.529 0.416 - 229.2 1 2 0 -0.0017 10 0 0 0 1.34E+07 1.36E+07 - - - 3.2983 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.15852.15852.2 0.0502 14-Aug K.GIAYIEFK[136.11].T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 947.5208 0.81 21698 15852 2 947.522263 474.7677 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3266.6 - 8.81E+06 - - - 1.5767 - 1.475 0.259 - 207.7 1 2 0 0.0015 8 0 0 0 6.23E+08 7.73E+08 - - - 2.1257 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.15853.15853.2 0.0019 20-Dec R.ILMVGLDAAGK.T "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|F5H1V1|F5H1V1_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|F5H6T5|F5H6T5_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|F8WDB3|F8WDB3_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 11 1086.6107 1.73 21699 15853 2 1086.611485 544.3126 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3266.8 - 1.09E+06 - - - 0.7068 - 2.274 0.422 - 416 1 2 0 0.0008 11 0 0 0 2.64E+08 1.52E+08 - - - 4.3801 0.997 230117_WJC_METTL3_WT_vs_EV_F03.15854.15854.2 1 12-Jun K.ILIWSGR.F "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 843.4967 1.46 21700 15854 2 843.496722 422.7556 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 9.75 3266.8 - 1.93E+06 - - - 0.0581 - 1.317 0.237 - 125 1 2 0 0 7 0 0 0 9.11E+07 6.25E+07 - - - 1.6639 0.9952 230117_WJC_METTL3_WT_vs_EV_F03.15859.15859.2 0.0033 20-Dec R.ILMVGLDAAGK[136.11].T "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|F5H1V1|F5H1V1_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|F5H6T5|F5H6T5_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|F8WDB3|F8WDB3_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 11 1094.6249 1.69 21703 15859 2 1094.622329 548.3197 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3267.5 - 4.64E+06 - - - -2.3643 - 1.854 0.271 - 378 1 2 0 -0.0026 11 0 0 0 2.64E+08 1.56E+08 - - - 2.7119 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.15861.15861.2 0.822 12-Jul K.ILIWSGR[166.11].F "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 853.5049 1.46 21705 15861 2 853.506607 427.7597 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 9.75 3267.6 - 2.87E+06 - - - 1.9496 - 1.413 0.191 - 152.6 1 2 0 0.0017 7 0 0 0 9.10E+07 6.25E+07 - - - 1.5466 0.9948 230117_WJC_METTL3_WT_vs_EV_F03.15865.15865.2 1.73 12-Jun R.LLLAFQK.K sp|Q14781|CBX2_HUMAN 1 831.5218 1.25 21706 15865 2 831.521425 416.7682 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.75 3268.1 - 2.12E+06 - - - -0.481 - 1.44 0.173 - 103.8 1 2 0 -0.0004 7 0 0 0 3.39E+07 2.72E+07 - - - 1.474 0.9917 230117_WJC_METTL3_WT_vs_EV_F03.15873.15873.2 0.21 16-Sep R.LLLQLEATK.N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1027.6277 9.34 21711 15873 2 1027.624165 514.8211 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3269.1 - 991753 - - - -3.4857 - 1.876 0.275 - 206.1 1 2 0 -0.0036 9 0 0 0 7.50E+08 8.03E+07 - - - 2.8912 0.9907 230117_WJC_METTL3_WT_vs_EV_F03.15875.15875.2 0.0129 18-Aug K.ILPEEITNLR.N sp|Q9H9A6|LRC40_HUMAN 1 1196.6765 0.99 21713 15875 2 1196.673132 599.3455 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3269.4 - 736742 - - - -2.8044 - 1.452 0.299 - 220.3 1 2 0 -0.0034 10 0 0 0 4.71E+07 4.76E+07 - - - 2.2894 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.15881.15881.2 0.184 12-Aug R.LYDGLFK.V "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 10 854.4538 1.89 21717 15881 2 854.45442 428.2342 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.83 3270.1 - 4.31E+06 - - - 0.7198 - 1.399 0.306 - 140.3 1 2 0 0.0006 7 0 0 0 2.09E+08 1.10E+08 - - - 2.3648 0.9948 230117_WJC_METTL3_WT_vs_EV_F03.15883.15883.2 0.934 12-Jul K.ILIEDWK[136.11].K "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A7I2V2T6|A0A7I2V2T6_HUMAN,tr|K7EPW7|K7EPW7_HUMAN" 4 923.5208 1.21 21718 15883 2 923.521254 462.7677 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 4.37 3270.3 - 790937 - - - 0.5252 - 1.356 0.143 - 148.7 1 2 0 0.0005 7 0 0 0 3.51E+07 2.90E+07 - - - 1.062 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.15892.15892.2 0.016 16-Sep R.MNVLADALK.S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 973.5267 1.34 21724 15892 2 973.525789 487.7706 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3271.5 - 845454 - - - -0.8875 - 1.906 0.326 - 200.5 1 2 0 -0.0009 9 0 0 0 6.39E+08 4.77E+08 - - - 3.3146 0.9888 230117_WJC_METTL3_WT_vs_EV_F03.15894.15894.2 0.594 12-May R.LFFVGSR.E "sp|Q9UM01|YLAT1_HUMAN,sp|Q92536|YLAT2_HUMAN,sp|Q01650|LAT1_HUMAN,tr|H0YJ95|H0YJ95_HUMAN,tr|A0A0C4DGL4|A0A0C4DGL4_HUMAN,tr|G3V4Z6|G3V4Z6_HUMAN" 6 824.4545 0.92 21726 15894 2 824.454272 413.2345 Y+L amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A7 PE=1 SV=2 9.75 3271.7 - 899950 - - - -0.245 - 1.13 0.199 - 51.9 2 2 0 -0.0002 7 0 0 0 2.78E+07 3.01E+07 - - - 0.7635 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.15899.15899.2 0.000431 16-Oct R.MNVLADALK[136.11].S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 981.5409 1.34 21729 15899 2 981.537542 491.7777 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3272.3 - 4.51E+06 - - - -3.3733 - 2.097 0.449 - 410.9 1 2 0 -0.0033 9 0 0 0 6.39E+08 4.77E+08 - - - 4.4986 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.15902.15902.2 0.0488 16-Jul K.VIIDTLITK[136.11].L sp|O15164|TIF1A_HUMAN 1 1022.6467 1.26 21732 15902 2 1022.648896 512.3306 Transcription intermediary factor 1-alpha OS=Homo sapiens OX=9606 GN=TRIM24 PE=1 SV=3 5.81 3272.6 - 753962 - - - 2.1493 - 1.501 0.243 - 97.8 1 2 0 0.0022 9 0 0 0 1.38E+07 1.09E+07 - - - 2.0101 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.15904.15904.2 0.0111 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.12 21734 15904 2 1235.76312 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3272.9 - 736688 - - - 2.3969 - 1.855 0.31 - 236.3 1 2 0 0.003 11 0 0 0 5.09E+08 4.53E+08 - - - 3.0013 0.9925 230117_WJC_METTL3_WT_vs_EV_F03.15907.15907.2 0.29 14-Jul R.GLVGIEFK.E sp|P15924|DESP_HUMAN 1 861.496 10.71 21735 15907 2 861.495551 431.7553 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 3273.3 - 9.26E+06 - - - -0.5258 - 1.348 0.17 - 131.3 1 2 0 -0.0005 8 0 0 0 2.25E+08 2.10E+07 - - - 1.1971 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.15909.15909.2 0.238 16-Sep R.LLLQLEATK[136.11].N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1035.6419 9.39 21737 15909 2 1035.641793 518.8282 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3273.5 - 4.51E+06 - - - -0.1487 - 1.871 0.351 - 225.9 1 2 0 -0.0002 9 0 0 0 7.31E+08 7.78E+07 - - - 3.4459 0.9811 230117_WJC_METTL3_WT_vs_EV_F03.15912.15912.2 0.8 12-Jun R.LFFVGSR[166.11].E "sp|Q9UM01|YLAT1_HUMAN,sp|Q92536|YLAT2_HUMAN,sp|Q01650|LAT1_HUMAN,tr|H0YJ95|H0YJ95_HUMAN,tr|A0A0C4DGL4|A0A0C4DGL4_HUMAN,tr|G3V4Z6|G3V4Z6_HUMAN" 6 834.4627 0.93 21740 15912 2 834.461315 418.2386 Y+L amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A7 PE=1 SV=2 9.75 3273.7 - 1.89E+06 - - - -1.7125 - 1.254 0.176 - 132.4 1 2 0 -0.0014 7 0 0 0 2.82E+07 3.04E+07 - - - 1.0577 0.9866 230117_WJC_METTL3_WT_vs_EV_F03.15913.15913.2 0.351 20-Oct K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.12 21741 15913 2 1245.766997 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3273.8 - 3.76E+06 - - - -1.1487 - 1.38 0.154 - 121.4 1 2 0 -0.0014 11 0 0 0 5.07E+08 4.52E+08 - - - 1.0493 1 230117_WJC_METTL3_WT_vs_EV_F03.15914.15914.2 5.83E-05 14/20 R.LVDAVLGAEIR[166.11].N "sp|Q9UBN7|HDAC6_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8Y758|A0A2R8Y758_HUMAN,tr|A0A2R8Y559|A0A2R8Y559_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 5 1164.6742 0.86 21742 15914 2 1164.676892 583.3444 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.37 3274 - 425618 - - - 2.3174 - 2.512 0.502 - 631.8 1 2 0 0.0027 11 0 0 0 5.48E+07 6.34E+07 - - - 5.2397 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.15920.15920.2 0.000153 16-Sep K.VLPVGVLYK[136.11].V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 994.6307 0.53 21746 15920 2 994.629463 498.3226 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3274.6 - 7.92E+06 - - - -1.1974 - 1.722 0.339 - 250.6 1 2 0 -0.0012 9 0 0 0 1.21E+08 2.28E+08 - - - 3.1168 0.9353 230117_WJC_METTL3_WT_vs_EV_F03.15923.15923.2 14 12-Jun K.DIILYVK[136.11].E "sp|Q7L1Q6|BZW1_HUMAN,tr|C9IZ80|C9IZ80_HUMAN,tr|H0Y503|H0Y503_HUMAN" 3 870.5306 1.69 21749 15923 2 870.531371 436.2726 Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1 5.83 3274.9 - 638745 - - - 0.8799 - 1.102 0.025 - 110.3 4 2 0 0.0008 7 0 0 0 2.01E+07 1.19E+07 - - - -0.7358 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.15926.15926.2 2.67E-05 18-Sep R.GYFEYIEENK.Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1290.5768 1.39 21752 15926 2 1290.575124 646.2957 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3275.3 - 256289 - - - -1.3242 - 1.626 0.449 - 161.9 1 2 0 -0.0017 10 0 0 0 9.31E+06 6.71E+06 - - - 3.7137 0.9866 230117_WJC_METTL3_WT_vs_EV_F03.15930.15930.2 1.83 12-Jun R.LYDGLFK[136.11].V "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 10 862.468 1.91 21754 15930 2 862.469015 432.2413 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.83 3275.7 - 3.49E+06 - - - 1.1711 - 1.383 0.046 - 84.8 2 2 0 0.001 7 0 0 0 2.06E+08 1.08E+08 - - - 0.2734 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.15932.15932.2 0.000528 18-Sep K.ILPEEITNLR[166.11].N sp|Q9H9A6|LRC40_HUMAN 1 1206.6848 0.99 21756 15932 2 1206.687282 604.3497 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3275.9 - 1.29E+06 - - - 2.0917 - 1.736 0.412 - 305.2 1 2 0 0.0025 10 0 0 0 4.71E+07 4.77E+07 - - - 3.6229 0.9911 230117_WJC_METTL3_WT_vs_EV_F03.15938.15938.2 0.358 14-Jun K.AVWLPAVK.A "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 882.5327 1.47 21760 15938 2 882.535439 442.2736 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.8 3276.6 - 1.55E+06 - - - 3.0764 - 1.037 0.255 - 129.7 1 2 0 0.0027 8 0 0 0 4.00E+07 2.72E+07 - - - 1.0332 0.9798 230117_WJC_METTL3_WT_vs_EV_F03.15939.15939.2 1.66 18-Apr R.ILIAK[136.11]PIMFR[166.11].G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1218.7641 0.76 21761 15939 2 1218.765502 610.3893 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3276.8 - 237653 - - - 1.1167 - 1.136 0.124 - 40.6 5 2 0 0.0014 10 0 0 0 3.75E+06 4.96E+06 - - - 0.0001 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.15943.15943.2 0.0072 14-Aug K.LLFVPC[160.03]SR[166.11].V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 1000.5403 0.87 21763 15943 2 1000.539799 501.2774 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.25 3277.3 - 1.13E+06 - - - -0.5427 - 1.745 0.312 - 195.9 1 2 0 -0.0005 8 0 0 0 4.50E+07 5.15E+07 - - - 3.0244 1 230117_WJC_METTL3_WT_vs_EV_F03.15944.15944.2 3.61E-05 16-Oct K.VIVPNMEFR.A sp|P55060|XPO2_HUMAN 1 1103.5798 1.29 21764 15944 2 1103.58112 552.7972 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.97 3277.4 - 901958 - - - 1.2405 - 2.051 0.515 - 425.4 1 2 0 0.0014 9 0 0 0 1.37E+08 1.07E+08 - - - 4.9225 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.15945.15945.2 0.513 14-Sep R.TLINELVK[136.11].G "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 7 936.5735 1.55 21765 15945 2 936.574682 469.294 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.66 3277.6 - 2.84E+06 - - - 1.2268 - 1.565 0.205 - 198.7 1 2 0 0.0011 8 0 0 0 1.28E+08 8.21E+07 - - - 1.9056 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.15949.15949.2 0.0548 18-Oct R.VPFLVAETPR.A sp|Q13131|AAPK1_HUMAN 1 1127.6339 7.96 21767 15949 2 1127.63408 564.8242 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4 5.97 3278.1 - 581184 - - - 0.1641 - 1.988 0.357 - 381.9 1 2 0 0.0002 10 0 0 0 1.29E+07 1.63E+06 - - - 3.5957 1 230117_WJC_METTL3_WT_vs_EV_F03.15950.15950.2 2.02E-06 18-Dec K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 8.03 21768 15950 2 1149.583972 575.7982 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3278.2 - 212531 - - - 1.8381 - 2.132 0.466 - 481.2 1 2 0 0.0021 10 0 0 0 1.07E+09 1.34E+08 - - - 4.5954 0.9754 230117_WJC_METTL3_WT_vs_EV_F03.15951.15951.2 1.77 16-Aug K.IYPVGYFTK.E "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 1086.575 14.07 21769 15951 2 1086.574714 544.2948 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.5 3278.3 - 1.42E+06 - - - -0.2476 - 1.224 0.079 - 150.3 1 2 0 -0.0003 9 0 0 0 6.85E+07 4.87E+06 - - - 0.2092 0.997 230117_WJC_METTL3_WT_vs_EV_F03.15955.15955.2 0.0648 14-Jul R.LLGWIQNK[136.11].L "sp|O75369|FLNB_HUMAN,sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN,tr|F8WE98|F8WE98_HUMAN" 11 978.5742 3.08 21771 15955 2 978.573252 490.2944 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 8.75 3278.8 - 1.33E+06 - - - -0.9708 - 1.511 0.267 - 114.4 1 2 0 -0.0009 8 0 0 0 7.75E+07 2.52E+07 - - - 2.2577 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.15957.15957.2 0.00217 18-Oct R.TVPLLLAESK[136.11].F sp|Q709C8|VP13C_HUMAN 1 1077.6525 0.85 21773 15957 2 1077.65383 539.8335 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 5.66 3279 - 598661 - - - 1.224 - 1.662 0.34 - 255.8 1 2 0 0.0013 10 0 0 0 1.00E+07 1.18E+07 - - - 2.9699 0.9885 230117_WJC_METTL3_WT_vs_EV_F03.15969.15969.2 1.22 14-Aug K.LIELLAGK[136.11].A sp|Q9NW08|RPC2_HUMAN 1 863.5572 1.07 21780 15969 2 863.558277 432.7859 DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2 6 3280.7 - 501875 - - - 1.3004 - 1.246 0.091 - 125.5 1 2 0 0.0011 8 0 0 0 1.76E+07 1.64E+07 - - - 0.3761 1 230117_WJC_METTL3_WT_vs_EV_F03.15981.15981.2 0.0287 18-Nov K.FAEAFEAIPR[166.11].A sp|P50990|TCPQ_HUMAN 1 1159.5901 8.53 21788 15981 2 1159.591039 580.8023 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3282.2 - 523084 - - - 0.7848 - 2.286 0.512 - 431.4 1 2 0 0.0009 10 0 0 0 1.06E+09 1.25E+08 - - - 5.1302 0.999 230117_WJC_METTL3_WT_vs_EV_F03.15982.15982.2 0.0183 24-Sep K.LGPGAGAGFGVLR.R "sp|Q9BUL5|PHF23_HUMAN,tr|I3L1N0|I3L1N0_HUMAN,tr|I3L410|I3L410_HUMAN,tr|I3L4Q4|I3L4Q4_HUMAN" 4 1170.6509 8.02 21789 15982 2 1170.652047 586.3327 PHD finger protein 23 OS=Homo sapiens OX=9606 GN=PHF23 PE=1 SV=1 9.75 3282.3 - 447835 - - - 0.9439 - 1.89 0.237 - 154.3 1 2 0 0.0011 13 0 0 0 2.34E+07 2.91E+06 - - - 2.4249 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.15984.15984.2 0.0265 16-Jun R.EPLSLINVR[166.11].K sp|Q96HS1|PGAM5_HUMAN 1 1049.6109 0.02 21791 15984 2 1049.61239 525.8127 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 6.1 3282.5 - 869630 - - - 1.4529 - 1.465 0.264 - 97.1 1 2 0 0.0015 9 0 0 0 3.56E+05 1.79E+07 - - - 2.0952 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.15994.15994.2 0.421 14-Jun K.LFIGNLPR[166.11].E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 938.5577 2.16 21797 15994 2 938.559807 470.2861 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3283.8 - 1.52E+06 - - - 2.2375 - 1.337 0.224 - 108.3 1 2 0 0.0021 8 0 0 0 3.58E+09 1.66E+09 - - - 1.5707 0.8864 230117_WJC_METTL3_WT_vs_EV_F03.15995.15995.2 0.409 12-Sep A.IIAELLR.L "sp|Q12768|WASC5_HUMAN,sp|P16444|DPEP1_HUMAN,sp|Q9Y4D8|HECD4_HUMAN,sp|Q7L2E3|DHX30_HUMAN,sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HJX8|A0A804HJX8_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A494C150|A0A494C150_HUMAN,tr|A0A804HJG8|A0A804HJG8_HUMAN,tr|F8VWT9|F8VWT9_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|H7BXY3|H7BXY3_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|J3KPF0|J3KPF0_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 24 826.5276 1.04 21798 15995 2 826.527704 414.2711 WASH complex subunit 5 OS=Homo sapiens OX=9606 GN=WASHC5 PE=1 SV=1 6 3283.9 - 3.35E+06 - - - 0.0786 - 1.688 0.21 - 245.9 1 1 0 0.0001 7 0 0 0 2.44E+08 2.35E+08 - - - 2.2509 0.9949 230117_WJC_METTL3_WT_vs_EV_F03.15997.15997.2 0.102 12-Jul R.MIEFVVR.E "sp|O15042|SR140_HUMAN,tr|E7ET15|E7ET15_HUMAN" 2 892.4841 1.48 21800 15997 2 892.487128 447.2493 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 5.75 3284.1 - 994680 - - - 3.4387 - 1.23 0.268 - 229.4 1 2 0 0.0031 7 0 0 0 4.54E+07 3.06E+07 - - - 1.6754 0.9022 230117_WJC_METTL3_WT_vs_EV_F03.15998.15998.2 1.2 14-May K.LLFVPC[160.03]SR.V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 990.5321 0.87 21801 15998 2 990.537597 496.2733 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.25 3284.2 - 896382 - - - 5.5778 - 0.981 0.199 - 42.9 1 2 0 0.0055 8 0 0 0 4.50E+07 5.15E+07 - - - 0.4512 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.16002.16002.2 0.000127 14-Sep K.FC[160.03]ELLIGR.G "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1006.527 562.04 21803 16002 2 1006.529525 504.2708 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.99 3284.7 - 620277 - - - 2.5215 - 1.926 0.478 - 329.5 1 2 0 0.0025 8 0 0 0 2.15E+08 3.83E+05 - - - 4.5475 0.9905 230117_WJC_METTL3_WT_vs_EV_F03.16004.16004.2 0.388 12-Jun K.VFGIQLK.E "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN" 3 803.4905 3.87 21805 16004 2 803.492017 402.7525 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 8.72 3284.8 - 2.67E+06 - - - 1.8569 - 1.168 0.138 - 108.2 1 2 0 0.0015 7 0 0 0 6.63E+07 1.71E+07 - - - 0.5519 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.16014.16014.2 0.0304 14-Jul K.ELPTVVFR.A sp|Q9BVP2|GNL3_HUMAN 1 959.544 0.89 21811 16014 2 959.547341 480.7793 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 6.1 3286 - 2.85E+06 - - - 3.4641 - 1.323 0.283 - 225 1 2 0 0.0033 8 0 0 0 1.26E+08 1.41E+08 - - - 1.9744 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.16021.16021.3 0.0166 14/36 K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 11.07 21815 16021 3 1149.58354 384.2012 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3286.9 - 846429 - - - 1.4623 - 2.225 0.418 - 341.9 1 2 0 0.0017 10 0 0 0 1.74E+07 1.57E+06 - - - 5.5355 0.9936 230117_WJC_METTL3_WT_vs_EV_F03.16023.16023.2 0.0624 14-Jul K.ELPTVVFR[166.11].A sp|Q9BVP2|GNL3_HUMAN 1 969.5523 0.89 21816 16023 2 969.555871 485.7834 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 6.1 3287.1 - 3.90E+06 - - - 3.6966 - 1.388 0.215 - 179.4 1 2 0 0.0036 8 0 0 0 1.27E+08 1.42E+08 - - - 1.6167 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.16027.16027.2 0.00165 16-Aug K.VYEAVELLK.S sp|Q8TEQ6|GEMI5_HUMAN 1 1062.5961 0.27 21818 16027 2 1062.598193 532.3053 Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3 4.53 3287.6 - 1.14E+06 - - - 1.9584 - 1.378 0.377 - 168.7 1 2 0 0.0021 9 0 0 0 1.93E+07 7.18E+07 - - - 2.7525 0.9959 230117_WJC_METTL3_WT_vs_EV_F03.16036.16036.2 0.107 12-Jul K.MIFVGIK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 806.4724 2.18 21825 16036 2 806.474288 404.2435 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 8.5 3288.6 - 830043 - - - 2.3014 - 1.315 0.19 - 167.4 1 2 0 0.0019 7 0 0 0 4.23E+07 1.93E+07 - - - 1.3114 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.16039.16039.2 0.214 14-Aug R.VLSIWEER[166.11].S "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1040.553 6.29 21826 16039 2 1040.553843 521.2838 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.53 3289 - 1.63E+06 - - - 0.7957 - 1.505 0.175 - 217.4 1 2 0 0.0008 8 0 0 0 2.74E+08 4.35E+07 - - - 1.5662 0.9315 230117_WJC_METTL3_WT_vs_EV_F03.16040.16040.2 4.9 12-Jul K.VWEGFIK.C "sp|Q92797|SYMPK_HUMAN,tr|M0R033|M0R033_HUMAN" 2 877.4698 1.75 21827 16040 2 877.472204 439.7422 Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2 5.97 3289.1 - 659565 - - - 2.7511 - 0.981 0.068 - 112.4 1 2 0 0.0024 7 0 0 0 1.98E+07 1.13E+07 - - - -0.5183 0.9961 230117_WJC_METTL3_WT_vs_EV_F03.16042.16042.2 0.0112 14-Jul R.WLPEEDFR.R sp|Q8IXT5|RB12B_HUMAN 1 1090.5084 1.62 21829 16042 2 1090.511911 546.2615 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 4.14 3289.4 - 489662 - - - 3.2563 - 1.409 0.235 - 177.4 1 2 0 0.0036 8 0 0 0 1.40E+07 8.68E+06 - - - 1.8097 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.16046.16046.2 0.0876 16-Aug K.LYENLGFVR.D "sp|Q147X3|NAA30_HUMAN,tr|J3KNC2|J3KNC2_HUMAN,tr|B4DK34|B4DK34_HUMAN" 3 1109.5869 2.5 21831 16046 2 1109.587482 555.8007 N-alpha-acetyltransferase 30 OS=Homo sapiens OX=9606 GN=NAA30 PE=1 SV=1 6 3289.8 - 362309 - - - 0.484 - 1.319 0.268 - 78.5 1 2 0 0.0005 9 0 0 0 1.05E+07 4.18E+06 - - - 1.8213 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.16048.16048.2 0.0121 20-Dec K.LLLIGDSGVGK.T "sp|P61006|RAB8A_HUMAN,sp|P51153|RAB13_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P59190|RAB15_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YL94|H0YL94_HUMAN,tr|A0A2R8YDI9|A0A2R8YDI9_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|G3V196|G3V196_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H0YLJ8|H0YLJ8_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN,tr|F5H157|F5H157_HUMAN" 19 1070.6336 1.46 21833 16048 2 1070.637215 536.3241 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.84 3290 - 2.31E+06 - - - 3.4139 - 2.417 0.377 - 413.4 1 2 0 0.0037 11 0 0 0 4.31E+08 2.95E+08 - - - 4.2118 0.9937 230117_WJC_METTL3_WT_vs_EV_F03.16054.16054.2 1.36 14-Oct R.LLAMAVIR[166.11].K sp|Q96EK4|THA11_HUMAN 1 895.5553 0.19 21836 16054 2 895.55614 448.7849 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 9.75 3290.8 - 849026 - - - 0.9782 - 1.544 0.064 - 280.9 1 2 0 0.0009 8 0 0 0 1.73E+07 9.22E+07 - - - 0.8235 0.9832 230117_WJC_METTL3_WT_vs_EV_F03.16056.16056.2 0.0978 16-Jul K.LYENLGFVR[166.11].D "sp|Q147X3|NAA30_HUMAN,tr|J3KNC2|J3KNC2_HUMAN,tr|B4DK34|B4DK34_HUMAN" 3 1119.5952 2.6 21838 16056 2 1119.596027 560.8049 N-alpha-acetyltransferase 30 OS=Homo sapiens OX=9606 GN=NAA30 PE=1 SV=1 6 3291 - 136204 - - - 0.7253 - 1.305 0.049 - 114 1 2 0 0.0008 9 0 0 0 9.78E+06 3.77E+06 - - - 0.1728 0.9946 230117_WJC_METTL3_WT_vs_EV_F03.16061.16061.2 0.718 14-Jul R.LEEIPLIK[136.11].S sp|Q14152|EIF3A_HUMAN 1 961.5939 0.92 21840 16061 2 961.593483 481.8042 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 3291.6 - 937911 - - - -0.469 - 1.697 0.109 - 98.8 1 2 0 -0.0005 8 0 0 0 8.07E+07 8.76E+07 - - - 1.441 0.9862 230117_WJC_METTL3_WT_vs_EV_F03.16062.16062.2 0.507 14-Jul R.LEEIPLIK.S sp|Q14152|EIF3A_HUMAN 1 953.5797 0.9 21841 16062 2 953.578019 477.7971 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 3291.7 - 624302 - - - -1.7985 - 1.617 0.117 - 117.5 1 2 0 -0.0017 8 0 0 0 7.91E+07 8.76E+07 - - - 1.354 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.16074.16074.2 0.159 16-Sep K.LTLLQVASR.Q sp|O95239|KIF4A_HUMAN 1 999.6077 2.17 21850 16074 2 999.60892 500.8111 Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3 9.75 3293.2 - 2.12E+06 - - - 1.2405 - 1.856 0.218 - 211.9 1 2 0 0.0012 9 0 0 0 2.88E+07 1.32E+07 - - - 2.4399 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.16076.16076.2 0.65 12-Jul K.IIAALFK[136.11].A "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 782.5146 1.67 21852 16076 2 782.515197 392.2646 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3293.4 - 796017 - - - 0.8128 - 1.567 0.157 - 108.8 1 2 0 0.0006 7 0 0 0 3.51E+07 2.10E+07 - - - 1.6236 0.9436 230117_WJC_METTL3_WT_vs_EV_F03.16077.16077.2 0.458 14-Aug R.PLELSDFR.M "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 975.5025 1.77 21853 16077 2 975.503718 488.7585 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.37 3293.5 - 550658 - - - 1.2014 - 1.676 0.285 - 242.8 1 1 0 0.0012 8 0 0 0 5.63E+07 3.18E+07 - - - 2.7031 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.16081.16081.2 0.162 12-Jul K.YGAFLLR.R "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 838.4701 1.16 21855 16081 2 838.470516 420.2423 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.75 3294 - 1.57E+06 - - - 0.4675 - 1.616 0.153 - 209.2 1 2 0 0.0004 7 0 0 0 4.00E+07 3.44E+07 - - - 1.6917 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.16082.16082.2 0.0462 12-Aug K.FGDFVLK[136.11].S "sp|P11172|UMPS_HUMAN,tr|F2Z303|F2Z303_HUMAN,tr|F2Z3P2|F2Z3P2_HUMAN,tr|F8WDG4|F8WDG4_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 5 832.4574 2.27 21856 16082 2 832.457065 417.236 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 5.84 3294.1 - 707391 - - - -0.4505 - 1.64 0.331 - 168.3 1 2 0 -0.0004 7 0 0 0 8.01E+07 3.54E+07 - - - 3.0531 0.975 230117_WJC_METTL3_WT_vs_EV_F03.16087.16087.2 7.37 14-Jul K.GGLGLILK.R "sp|O75832|PSD10_HUMAN,tr|B1AJY5|B1AJY5_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 3 769.5062 1.59 21859 16087 2 769.50672 385.7604 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 8.75 3294.7 - 584495 - - - 0.7082 - 1.293 0.013 - 120 1 2 0 0.0005 8 0 0 0 8.48E+07 5.32E+07 - - - -0.0882 0.9774 230117_WJC_METTL3_WT_vs_EV_F03.16090.16090.2 0.321 14-Aug R.GFVLYPVK.Y sp|P62487|RPB7_HUMAN 1 921.5324 0.01 21860 16090 2 921.535287 461.7735 DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1 8.59 3295.1 - 837084 - - - 3.1437 - 0.949 0.203 - 178.2 1 2 0 0.0029 8 0 0 0 2.06E+07 1.77E+09 - - - 0.3816 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.16092.16092.2 0.0046 18-Oct K.AMTILLEEAK.A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1117.6053 2.3 21862 16092 2 1117.60798 559.8099 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3295.4 - 227473 - - - 2.4007 - 2.15 0.389 - 263.8 1 2 0 0.0027 10 0 0 0 4.40E+07 1.92E+07 - - - 4.05 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.16093.16093.2 0.00319 18-Aug K.ILVEEMAPLK.G "sp|Q16670|ZSC26_HUMAN,tr|A0A087WXM4|A0A087WXM4_HUMAN,tr|A0A024RCN4|A0A024RCN4_HUMAN,tr|A0A087X2F1|A0A087X2F1_HUMAN" 4 1141.6417 999 21863 16093 2 1141.646784 571.8281 Zinc finger and SCAN domain-containing protein 26 OS=Homo sapiens OX=9606 GN=ZSCAN26 PE=1 SV=2 4.53 3295.5 - 214774 - - - 4.469 - 1.835 0.349 - 91.5 1 2 0 0.0051 10 0 0 0 3.63E+06 0.00E+00 - - - 3.3116 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.16101.16101.2 0.0199 18-Sep K.AMTILLEEAK[136.11].A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1125.6195 2.3 21869 16101 2 1125.619746 563.817 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3296.5 - 212980 - - - 0.2212 - 1.73 0.224 - 219.1 1 2 0 0.0002 10 0 0 0 4.40E+07 1.92E+07 - - - 2.2254 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.16102.16102.2 0.0583 18-Aug K.LLADELISPK[136.11].D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1105.6474 1.12 21870 16102 2 1105.648174 553.831 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3296.6 - 210713 - - - 0.6765 - 1.681 0.255 - 100.9 1 2 0 0.0007 10 0 0 0 7.25E+07 6.49E+07 - - - 2.374 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.16107.16107.2 0.268 12-Aug R.LSAIFLR.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 818.5014 1.39 21873 16107 2 818.503094 410.258 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3297.3 - 1.17E+06 - - - 2.0403 - 1.682 0.124 - 199.4 1 2 0 0.0017 7 0 0 0 4.92E+07 3.54E+07 - - - 1.6039 0.8538 230117_WJC_METTL3_WT_vs_EV_F03.16108.16108.2 4.92 14-May K.LIPVLQVK[136.11].L sp|Q63ZY3|KANK2_HUMAN 1 916.6201 2.42 21874 16108 2 916.621988 459.3173 KN motif and ankyrin repeat domain-containing protein 2 OS=Homo sapiens OX=9606 GN=KANK2 PE=1 SV=1 8.75 3297.4 - 1.28E+06 - - - 2.0717 - 0.776 0.084 - 54.1 2 2 0 0.0019 8 0 0 0 5.09E+07 2.10E+07 - - - -1.2385 0.999 230117_WJC_METTL3_WT_vs_EV_F03.16109.16109.2 0.00992 14-Aug R.LSYTQLLR.R "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 992.5655 5.05 21875 16109 2 992.568292 497.29 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.75 3297.5 - 581498 - - - 2.8321 - 1.623 0.342 - 155.1 1 2 0 0.0028 8 0 0 0 2.47E+07 4.89E+06 - - - 3.0267 0.9945 230117_WJC_METTL3_WT_vs_EV_F03.16111.16111.2 1.62 14-Jul K.LFIGNLPR.E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 928.5494 2.15 21876 16111 2 928.551364 465.282 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3297.7 - 1.35E+08 - - - 2.0753 - 1.366 0.138 - 168.9 1 2 0 0.0019 8 0 0 0 3.58E+09 1.66E+09 - - - 1.0003 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.16113.16113.2 2.05 12-Aug R.LSAIFLR[166.11].L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 828.5097 1.43 21877 16113 2 828.510873 415.2621 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3297.9 - 1.10E+06 - - - 1.423 - 1.82 0.161 - 185.9 1 2 0 0.0012 7 0 0 0 4.91E+07 3.45E+07 - - - 2.1272 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.16116.16116.2 0.0582 12-May R.EYFYGFR.G "sp|Q92989|CLP1_HUMAN,tr|E9PL17|E9PL17_HUMAN" 2 980.4392 3.14 21880 16116 2 980.441157 491.2269 Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1 6.1 3298.2 - 450008 - - - 1.9777 - 1.091 0.242 - 79.5 1 2 0 0.0019 7 0 0 0 4.93E+06 1.57E+06 - - - 1.1038 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.16130.16130.2 0.000292 16-Aug R.FDDPLLGPR[166.11].R "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 8 1038.5374 0.93 21888 16130 2 1038.536914 520.276 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.21 3299.9 - 234505 - - - -0.4343 - 1.546 0.466 - 154.6 1 2 0 -0.0005 9 0 0 0 8.31E+07 8.97E+07 - - - 3.7432 1 230117_WJC_METTL3_WT_vs_EV_F03.16137.16137.2 1.56E-05 18-Dec K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 426.64 21893 16137 2 1146.630514 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3300.8 - 4.44E+06 - - - 1.7783 - 2.214 0.516 - 430.2 1 2 0 0.002 10 0 0 0 5.30E+09 1.24E+07 - - - 5.0701 0.999 230117_WJC_METTL3_WT_vs_EV_F03.16139.16139.2 0.00833 12-Jul R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 31.21 21895 16139 2 806.393883 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 3301.1 - 703040 - - - 2.004 - 1.599 0.272 - 168.2 1 2 0 0.0016 7 0 0 0 5.81E+07 1.86E+06 - - - 2.5367 0.9942 230117_WJC_METTL3_WT_vs_EV_F03.16140.16140.2 0.076 20-Sep K.C[160.03]ILVASPGFVR.E sp|Q9BRX2|PELO_HUMAN 1 1217.6591 3.44 21896 16140 2 1217.66459 609.8368 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 8.25 3301.2 - 486210 - - - 4.5382 - 1.9 0.199 - 222.9 1 2 0 0.0055 11 0 0 0 1.62E+07 4.71E+06 - - - 2.2454 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.16146.16146.2 0.425 14-Jul M.VLLTMIAR.V sp|O75396|SC22B_HUMAN 1 915.5576 0.76 21900 16146 2 915.559686 458.7861 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 9.72 3301.9 - 2.21E+06 - - - 2.3232 - 1.494 0.339 - 181.2 1 2 0 0.0021 8 0 0 0 8.18E+07 1.08E+08 - - - 2.755 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.16147.16147.2 0.0404 16-Sep K.VVDVLDSIK.T sp|P00918|CAH2_HUMAN 1 986.5648 0.82 21901 16147 2 986.565717 494.2897 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.21 3302 - 1.47E+06 - - - 0.9173 - 1.576 0.329 - 183.3 1 2 0 0.0009 9 0 0 0 2.31E+07 2.81E+07 - - - 2.7867 1 230117_WJC_METTL3_WT_vs_EV_F03.16148.16148.2 1.04E-05 20-Oct K.NSLESYAFNMK.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1302.5914 81.29 21902 16148 2 1302.593061 652.303 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6 3302.2 - 1.06E+06 - - - 1.246 - 2.286 0.525 - 555.7 1 2 0 0.0016 11 0 0 0 1.32E+07 1.63E+05 - - - 5.1548 0.968 230117_WJC_METTL3_WT_vs_EV_F03.16149.16149.2 0.192 20-Jun K.C[160.03]ILVASPGFVR[166.11].E sp|Q9BRX2|PELO_HUMAN 1 1227.6673 3.44 21903 16149 2 1227.671069 614.8409 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 8.25 3302.3 - 465764 - - - 3.0424 - 1.42 0.044 - 99 3 2 0 0.0037 11 0 0 0 1.62E+07 4.71E+06 - - - 0.1003 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.16156.16156.2 0.0207 16-Sep R.IVLNGIDLK.A sp|O15294|OGT1_HUMAN 1 983.6015 2.03 21908 16156 2 983.604578 492.808 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 5.84 3303.1 - 1.26E+06 - - - 3.0968 - 1.873 0.226 - 160.3 1 2 0 0.003 9 0 0 0 2.56E+07 1.26E+07 - - - 2.5248 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16157.16157.2 0.000779 16-Aug K.AFIGFEGVK.G sp|P15924|DESP_HUMAN 1 966.5175 2.3 21909 16157 2 966.517308 484.266 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.05 3303.2 - 801447 - - - -0.1655 - 1.524 0.475 - 179.4 1 2 0 -0.0002 9 0 0 0 6.77E+07 2.95E+07 - - - 3.7683 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.16161.16161.2 0.00236 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.12 21912 16161 2 1235.762484 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3303.7 - 2.08E+06 - - - 1.8822 - 2.012 0.353 - 251.5 1 2 0 0.0023 11 0 0 0 5.09E+08 4.53E+08 - - - 3.5388 0.994 230117_WJC_METTL3_WT_vs_EV_F03.16162.16162.2 0.396 12-Aug R.LIFDNLK.K "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P54707|AT12A_HUMAN,sp|P20648|ATP4A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 11 861.496 1.09 21913 16162 2 861.497776 431.7553 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.84 3303.8 - 392796 - - - 2.0569 - 1.249 0.161 - 148.6 1 2 0 0.0018 7 0 0 0 6.31E+07 5.76E+07 - - - 0.9341 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.16164.16164.2 0.0297 20-Nov K.LLDSITVPVAR[166.11].A sp|O00203|AP3B1_HUMAN 1 1192.7055 1.31 21915 16164 2 1192.707394 597.36 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3304 - 174230 - - - 1.5939 - 2.305 0.413 - 342.3 1 2 0 0.0019 11 0 0 0 2.64E+07 2.01E+07 - - - 4.3499 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.16167.16167.2 0.165 20-Sep K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.08 21917 16167 2 1245.770718 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3304.2 - 1.15E+06 - - - 1.8382 - 1.509 0.363 - 187.8 1 2 0 0.0023 11 0 0 0 4.98E+07 4.60E+07 - - - 2.8345 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.16169.16169.2 0.266 12-Jul K.MFEFYER.V "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 13 1020.4375 2.15 21919 16169 2 1020.44021 511.226 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3304.4 - 1.27E+06 - - - 2.6528 - 1.355 0.209 - 232.5 1 2 0 0.0027 7 0 0 0 2.50E+07 1.16E+07 - - - 1.5464 0.9271 230117_WJC_METTL3_WT_vs_EV_F03.16170.16170.2 0.0158 14-Aug F.AFLWAGGR.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A1W2PNG3|A0A1W2PNG3_HUMAN" 12 876.4606 1.21 21920 16170 2 876.462021 439.2376 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.79 3304.4 - 783348 - - - 1.5962 - 1.571 0.272 - 204 1 1 0 0.0014 8 0 0 0 1.95E+09 1.61E+09 - - - 2.4119 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.16175.16175.2 0.619 12-Jul K.ILPDILK[136.11].K "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 818.5357 2.45 21923 16175 2 818.536066 410.2751 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 3305 - 4.66E+06 - - - 0.4581 - 1.433 0.173 - 114.4 1 2 0 0.0004 7 0 0 0 1.05E+08 4.26E+07 - - - 1.4586 0.9892 230117_WJC_METTL3_WT_vs_EV_F03.16176.16176.2 0.327 12-Jun K.ILPDILK.K "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 810.5215 1.87 21924 16176 2 810.521332 406.268 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 3305.1 - 1.16E+07 - - - -0.1962 - 1.257 0.154 - 88.4 2 2 0 -0.0002 7 0 0 0 1.06E+08 5.69E+07 - - - 0.7687 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.16179.16179.2 0.067 18-Aug R.LTPLQLEIQR[166.11].V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1219.7164 1.18 21927 16179 2 1219.715746 610.8655 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 3305.3 - 2.57E+06 - - - -0.5296 - 1.646 0.336 - 223 1 2 0 -0.0006 10 0 0 0 4.51E+07 3.81E+07 - - - 2.9135 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.16180.16180.2 0.0012 20-Nov K.LLDSITVPVAR.A sp|O00203|AP3B1_HUMAN 1 1182.6972 1.31 21928 16180 2 1182.69572 592.3559 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3305.4 - 2.24E+06 - - - -1.2708 - 2.102 0.367 - 308.8 1 2 0 -0.0015 11 0 0 0 2.64E+07 2.01E+07 - - - 3.7609 0.98 230117_WJC_METTL3_WT_vs_EV_F03.16181.16181.2 1.44 12-Jun K.AFIVELR[166.11].Q sp|O43318|M3K7_HUMAN 1 856.5046 0.93 21929 16181 2 856.50484 429.2596 Mitogen-activated protein kinase kinase kinase 7 OS=Homo sapiens OX=9606 GN=MAP3K7 PE=1 SV=1 6.05 3305.4 - 1.35E+06 - - - 0.2697 - 1.3 0.04 - 131.6 1 2 0 0.0002 7 0 0 0 8.94E+06 9.63E+06 - - - 0.1677 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.16190.16190.2 0.0405 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 419.88 21935 16190 2 1154.643097 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3306.6 - 806742 - - - 0.3655 - 1.897 0.364 - 252.3 1 2 0 0.0004 10 0 0 0 5.23E+09 1.25E+07 - - - 3.5166 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.16194.16194.2 0.961 14-Oct R.LMGLEALK.S "sp|P48643|TCPE_HUMAN,tr|D6RIZ7|D6RIZ7_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0Y914|H0Y914_HUMAN" 4 873.4994 5.85 21937 16194 2 873.499866 437.757 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 3307.2 - 3.94E+06 - - - 0.5621 - 1.789 0.263 - 280.8 1 2 0 0.0005 8 0 0 0 2.96E+09 5.05E+08 - - - 2.7376 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.16195.16195.2 0.0939 18-Oct K.LLADELISPK.D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1097.6332 1.11 21938 16195 2 1097.634165 549.8239 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3307.2 - 832723 - - - 0.8555 - 2.065 0.32 - 276 1 2 0 0.0009 10 0 0 0 7.25E+07 6.51E+07 - - - 3.4283 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.16198.16198.2 0.0829 14-Aug R.LLNTFLER.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 8 1004.5655 1.38 21940 16198 2 1004.565749 503.29 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3307.5 - 869216 - - - 0.2668 - 1.798 0.371 - 185.5 1 2 0 0.0003 8 0 0 0 1.90E+08 1.38E+08 - - - 3.5505 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.16201.16201.2 0.0533 14-Jul K.FYSFALDK.T sp|Q96T58|MINT_HUMAN 1 989.4858 0.9 21942 16201 2 989.487571 495.7502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.83 3307.8 - 848201 - - - 1.7555 - 1.383 0.284 - 116 1 2 0 0.0017 8 0 0 0 3.78E+07 4.18E+07 - - - 2.116 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.16206.16206.2 0.0335 18-Oct R.LTPLQLEIQR.V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1209.7081 1.18 21945 16206 2 1209.707273 605.8613 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 3308.5 - 1.05E+06 - - - -0.7018 - 1.696 0.334 - 527.4 1 2 0 -0.0008 10 0 0 0 4.51E+07 3.81E+07 - - - 2.9822 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.16214.16214.2 0.00138 12-Jun K.LFQLYPR.N sp|Q8IXM3|RM41_HUMAN 1 935.5229 1.56 21949 16214 2 935.523412 468.7687 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 8.75 3309.4 - 1.96E+06 - - - 0.5601 - 1.513 0.339 - 145.6 1 2 0 0.0005 7 0 0 0 9.34E+07 6.00E+07 - - - 2.8568 0.996 230117_WJC_METTL3_WT_vs_EV_F03.16216.16216.2 1.42 22-Aug K.LGALTAEEIALK.M sp|Q13601|KRR1_HUMAN 1 1227.7075 1.15 21951 16216 2 1227.709804 614.861 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3309.5 - 729114 - - - 1.9141 - 1.229 0.219 - 147.3 1 2 0 0.0024 12 0 0 0 1.80E+08 1.56E+08 - - - 1.2003 0.9903 230117_WJC_METTL3_WT_vs_EV_F03.16224.16224.2 0.149 18-Jul K.IPVSGPFLVK.T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1055.6379 1.26 21955 16224 2 1055.63726 528.8262 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3310.5 - 189615 - - - -0.6233 - 1.385 0.184 - 78.5 4 2 0 -0.0007 10 0 0 0 1.77E+08 1.41E+08 - - - 1.04 0.9421 230117_WJC_METTL3_WT_vs_EV_F03.16225.16225.2 0.00135 22-Nov R.GLLQDDAHPTLV.T "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1277.6616 - 21956 16225 2 1277.660987 639.8381 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3310.6 - 276958 - - - -0.4532 - 1.984 0.367 - 222.2 1 1 0 -0.0006 12 0 0 0 - - - - - 3.5541 0.9641 230117_WJC_METTL3_WT_vs_EV_F03.16226.16226.2 0.00138 22-Oct K.LGALTAEEIALK[136.11].M sp|Q13601|KRR1_HUMAN 1 1235.7217 1.15 21957 16226 2 1235.712948 618.8681 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3310.7 - 689760 - - - -7.0453 - 1.938 0.43 - 293.8 1 2 0 -0.0087 12 0 0 0 1.80E+08 1.56E+08 - - - 3.9552 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.16232.16232.2 0.00109 18-Oct K.LGLTEDQFIR.T "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1190.6295 3.05 21959 16232 2 1190.62835 596.322 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.37 3311.5 - 1.13E+06 - - - -0.9978 - 1.654 0.394 - 250.6 1 2 0 -0.0012 10 0 0 0 1.90E+07 6.22E+06 - - - 3.3553 0.9898 230117_WJC_METTL3_WT_vs_EV_F03.16233.16233.2 1.41 12-Jun K.DVLLPLK.S sp|Q9Y385|UB2J1_HUMAN 1 796.5058 1.13 21960 16233 2 796.507614 399.2602 Ubiquitin-conjugating enzyme E2 J1 OS=Homo sapiens OX=9606 GN=UBE2J1 PE=1 SV=2 5.84 3311.6 - 953509 - - - 2.226 - 1.298 0.098 - 150.1 1 2 0 0.0018 7 0 0 0 1.45E+07 1.28E+07 - - - 0.5907 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.16235.16235.2 0.406 12-Jul K.LMVIFSK.V "sp|Q9BRK5|CAB45_HUMAN,tr|A0A5F9UJX7|A0A5F9UJX7_HUMAN,tr|A0A5F9UP49|A0A5F9UP49_HUMAN,tr|G3V1E2|G3V1E2_HUMAN,tr|H0Y3T6|H0Y3T6_HUMAN" 5 836.483 0.36 21962 16235 2 836.482488 419.2488 45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1 8.75 3311.8 - 1.06E+06 - - - -0.6085 - 1.578 0.22 - 144.3 1 2 0 -0.0005 7 0 0 0 2.79E+07 7.81E+07 - - - 2.1111 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.16240.16240.2 7.58E-05 22-Oct R.VFASELNAGIIK[136.11].T "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1268.722 1.87 21965 16240 2 1268.727377 635.3683 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.97 3312.4 - 116338 - - - 4.2476 - 2.05 0.432 - 235.2 1 2 0 0.0054 12 0 0 0 2.22E+07 1.19E+07 - - - 4.1188 0.9005 230117_WJC_METTL3_WT_vs_EV_F03.16244.16244.2 0.039 18-Aug F.LLVGTQIDLR.D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1126.671 1.39 21967 16244 2 1126.669373 564.3428 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.84 3312.8 - 273945 - - - -1.4521 - 1.902 0.379 - 205.2 1 1 0 -0.0016 10 0 0 0 2.13E+07 1.54E+07 - - - 3.6343 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.16247.16247.2 0.0707 18-Aug K.LGLTEDQFIR[166.11].T "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1200.6378 3.05 21969 16247 2 1200.640937 601.3262 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.37 3313.2 - 119299 - - - 2.6061 - 1.496 0.245 - 120.4 1 2 0 0.0031 10 0 0 0 1.90E+07 6.22E+06 - - - 1.9739 0.9874 230117_WJC_METTL3_WT_vs_EV_F03.16253.16253.2 0.788 16-Jun K.VILTSPLIR[166.11].D sp|Q96SI9|STRBP_HUMAN 1 1020.6571 2.34 21971 16253 2 1020.657534 511.3358 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 9.72 3314 - 264315 - - - 0.438 - 1.291 0.107 - 71.1 2 2 0 0.0004 9 0 0 0 6.08E+07 2.60E+07 - - - 0.4356 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.16262.16262.2 1.04 12-Jul K.LIIFDAR.Q "sp|Q13613|MTMR1_HUMAN,tr|Q8NEC6|Q8NEC6_HUMAN,tr|F8WA39|F8WA39_HUMAN,tr|H0YDX3|H0YDX3_HUMAN" 4 846.4963 4.61 21973 16262 2 846.496798 424.2554 Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4 5.84 3315.5 - 1.13E+06 - - - 0.5422 - 1.423 0.132 - 150.7 1 2 0 0.0005 7 0 0 0 9.92E+07 2.15E+07 - - - 1.1336 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.16266.16266.2 0.0215 14-Aug R.LLNTFLER[166.11].L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 8 1014.5738 1.34 21975 16266 2 1014.575119 508.2942 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3316 - 3.64E+06 - - - 1.3483 - 1.511 0.302 - 178.8 1 2 0 0.0014 8 0 0 0 1.85E+08 1.38E+08 - - - 2.516 1 230117_WJC_METTL3_WT_vs_EV_F03.16269.16269.2 8.35E-06 22-Nov K.VLVALASEELAK[136.11].G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1249.7373 1.57 21978 16269 2 1249.739716 625.8759 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.53 3316.4 - 738762 - - - 1.93 - 2.213 0.502 - 330.9 1 2 0 0.0024 12 0 0 0 5.51E+07 3.51E+07 - - - 4.8381 0.9925 230117_WJC_METTL3_WT_vs_EV_F03.16271.16271.2 0.0836 16-Jul R.IGFGSFVEK.T "sp|P05556|ITB1_HUMAN,sp|P18564|ITB6_HUMAN,tr|A0A7I2V2F9|A0A7I2V2F9_HUMAN,tr|A0A087WXP3|A0A087WXP3_HUMAN,tr|A0A7I2V5T3|A0A7I2V5T3_HUMAN,tr|H7C4K3|H7C4K3_HUMAN,tr|E7EUI6|E7EUI6_HUMAN,tr|E9PEE8|E9PEE8_HUMAN,tr|A0A7I2V5Z8|A0A7I2V5Z8_HUMAN,tr|A0A7I2V348|A0A7I2V348_HUMAN,tr|C9JPK5|C9JPK5_HUMAN" 11 982.5124 2.98 21980 16271 2 982.511199 492.2635 Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1 PE=1 SV=2 6 3316.6 - 331684 - - - -1.2051 - 1.335 0.226 - 81.8 1 2 0 -0.0012 9 0 0 0 1.95E+07 6.55E+06 - - - 1.5458 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.16274.16274.2 0.124 16-Jul R.IGFGSFVEK[136.11].T "sp|P05556|ITB1_HUMAN,sp|P18564|ITB6_HUMAN,tr|A0A7I2V2F9|A0A7I2V2F9_HUMAN,tr|A0A087WXP3|A0A087WXP3_HUMAN,tr|A0A7I2V5T3|A0A7I2V5T3_HUMAN,tr|H7C4K3|H7C4K3_HUMAN,tr|E7EUI6|E7EUI6_HUMAN,tr|E9PEE8|E9PEE8_HUMAN,tr|A0A7I2V5Z8|A0A7I2V5Z8_HUMAN,tr|A0A7I2V348|A0A7I2V348_HUMAN,tr|C9JPK5|C9JPK5_HUMAN" 11 990.5266 2.7 21981 16274 2 990.528921 496.2706 Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1 PE=1 SV=2 6 3317 - 388318 - - - 2.3604 - 1.388 0.201 - 68.1 1 2 0 0.0023 9 0 0 0 1.66E+07 6.13E+06 - - - 1.4734 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.16282.16282.2 0.153 16-Oct R.IGLINDMVR[166.11].F sp|Q14152|EIF3A_HUMAN 1 1039.5724 2.05 21985 16282 2 1039.573017 520.7935 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.84 3318 - 772437 - - - 0.6214 - 1.777 0.234 - 240.3 1 2 0 0.0006 9 0 0 0 1.49E+08 7.27E+07 - - - 2.4324 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16283.16283.2 0.322 20-Nov R.IDALLAVDPPR.A sp|P50219|MNX1_HUMAN 1 1178.6659 1.59 21986 16283 2 1178.666271 590.3402 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3318.1 - 345171 - - - 0.2952 - 2.219 0.277 - 390.2 1 2 0 0.0003 11 0 0 0 1.74E+07 1.09E+07 - - - 3.243 1 230117_WJC_METTL3_WT_vs_EV_F03.16284.16284.2 3.30E-07 22-Nov K.VLVALASEELAK.G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1241.7231 1.57 21987 16284 2 1241.724572 621.8688 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.53 3318.2 - 1.64E+06 - - - 1.1822 - 2.3 0.516 - 356.7 1 2 0 0.0015 12 0 0 0 5.51E+07 3.51E+07 - - - 5.0432 0.9945 230117_WJC_METTL3_WT_vs_EV_F03.16287.16287.2 0.211 16-Oct K.ALLSTVLSR.S "sp|Q5H9F3|BCORL_HUMAN,tr|H7C4B2|H7C4B2_HUMAN" 2 958.5811 2.49 21990 16287 2 958.585447 480.2978 BCL-6 corepressor-like protein 1 OS=Homo sapiens OX=9606 GN=BCORL1 PE=1 SV=1 9.79 3318.6 - 351443 - - - 4.5025 - 2.06 0.156 - 234.4 1 2 0 0.0043 9 0 0 0 1.11E+07 4.48E+06 - - - 2.2827 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.16292.16292.2 0.0524 18-Sep K.IPVSGPFLVK[136.11].T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1063.6521 1.26 21993 16292 2 1063.651728 532.8333 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3319.2 - 2.31E+06 - - - -0.3667 - 1.486 0.21 - 229.4 1 2 0 -0.0004 10 0 0 0 1.77E+08 1.41E+08 - - - 1.6975 1 230117_WJC_METTL3_WT_vs_EV_F03.16294.16294.2 0.000211 20-Nov R.LLTGVEYVVGR.K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1204.6816 1.47 21995 16294 2 1204.683737 603.3481 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3319.4 - 793517 - - - 1.7963 - 2.367 0.546 - 376.5 1 2 0 0.0022 11 0 0 0 2.78E+07 1.89E+07 - - - 5.404 1 230117_WJC_METTL3_WT_vs_EV_F03.16295.16295.2 0.000152 20-Nov R.LLTGVEYVVGR[166.11].K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1214.6898 1.47 21996 16295 2 1214.691677 608.3522 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3319.5 - 627160 - - - 1.5099 - 2.291 0.465 - 373.5 1 2 0 0.0018 11 0 0 0 2.78E+07 1.89E+07 - - - 4.7175 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.16296.16296.2 0.0748 22-Jul R.VFASELNAGIIK.T "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1260.7078 1.81 21997 16296 2 1260.711884 631.3612 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.97 3319.7 - 285003 - - - 3.249 - 1.249 0.353 - 81.2 1 2 0 0.0041 12 0 0 0 2.15E+07 1.19E+07 - - - 2.232 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.16301.16301.2 0.24 12-Jul K.LMFEELR.N sp|Q9Y3I0|RTCB_HUMAN 1 936.4739 0.99 22000 16301 2 936.475963 469.2442 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.53 3320.3 - 2.15E+06 - - - 2.2147 - 1.43 0.296 - 192 1 2 0 0.0021 7 0 0 0 9.33E+07 9.42E+07 - - - 2.3599 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.16302.16302.2 0.165 12-Jul K.LMFEELR[166.11].N sp|Q9Y3I0|RTCB_HUMAN 1 946.4822 0.99 22001 16302 2 946.484178 474.2484 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.53 3320.3 - 1.76E+06 - - - 2.1332 - 1.125 0.375 - 120.1 1 2 0 0.002 7 0 0 0 9.33E+07 9.42E+07 - - - 2.1833 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.16303.16303.2 0.00217 20-Aug K.VLEVPPVVYSR[166.11].Q "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1266.7211 0.64 22002 16303 2 1266.722352 634.3678 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 5.97 3320.4 - 209273 - - - 0.9544 - 1.967 0.427 - 207.6 1 2 0 0.0012 11 0 0 0 8.23E+06 1.28E+07 - - - 4.0246 0.9937 230117_WJC_METTL3_WT_vs_EV_F03.16308.16308.2 1.37 16-Jul R.SAVYPLLYR.D "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H7C184|H7C184_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1080.5968 1.59 22005 16308 2 1080.600263 541.3057 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 8.31 3321 - 513833 - - - 3.2223 - 1.69 0.111 - 176 1 2 0 0.0035 9 0 0 0 9.88E+06 6.20E+06 - - - 1.3778 0.9678 230117_WJC_METTL3_WT_vs_EV_F03.16319.16319.2 3.22 26-Jun R.IAGPAIPSVVAYPK.R "tr|A0A7I2YQF4|A0A7I2YQF4_HUMAN,tr|A0A7I2V549|A0A7I2V549_HUMAN,tr|A0A7I2V602|A0A7I2V602_HUMAN" 3 1381.7969 0.77 22014 16319 2 1381.800139 691.9057 Non-specific serine\threonine protein kinase OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=1 8.59 3322.2 - 821637 - - - 2.3173 - 1.179 0.07 - 91.3 2 2 0 0.0032 14 0 0 0 1.68E+07 2.17E+07 - - - -0.1642 0.8765 230117_WJC_METTL3_WT_vs_EV_F03.16324.16324.2 12.2 12-May R.KDLDLAK.V "sp|Q9C0A6|SETD5_HUMAN,tr|H0Y3R4|H0Y3R4_HUMAN,tr|A0A804HKJ9|A0A804HKJ9_HUMAN,tr|H7C1F2|H7C1F2_HUMAN,tr|E7EWN3|E7EWN3_HUMAN" 5 801.4596 10.31 22017 16324 2 801.461471 401.7371 Histone-lysine N-methyltransferase SETD5 OS=Homo sapiens OX=9606 GN=SETD5 PE=1 SV=2 5.96 3322.9 - 1.35E+06 - - - 2.3108 - 1.004 0.003 - 100.3 2 2 0 0.0019 7 0 0 0 6.37E+07 6.18E+06 - - - -1.0592 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.16325.16325.2 0.521 18-Aug K.LVALAVIDEK[136.11].N sp|Q96JJ7|TMX3_HUMAN 1 1077.6525 1.75 22018 16325 2 1077.653307 539.8335 Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2 4.37 3323 - 114964 - - - 0.7386 - 1.766 0.15 - 94.8 1 2 0 0.0008 10 0 0 0 1.40E+07 8.01E+06 - - - 1.7361 0.9965 230117_WJC_METTL3_WT_vs_EV_F03.16329.16329.2 0.148 12-Jul K.LWVLETK[136.11].E "sp|Q15061|WDR43_HUMAN,tr|C9JEE7|C9JEE7_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 3 895.5259 7.42 22019 16329 2 895.525386 448.7702 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3323.6 - 670113 - - - -0.5226 - 1.495 0.208 - 145.6 1 2 0 -0.0005 7 0 0 0 3.70E+08 4.99E+07 - - - 1.8513 0.9785 230117_WJC_METTL3_WT_vs_EV_F03.16331.16331.2 0.0165 12-Jul R.EAYYWLR.H sp|P46977|STT3A_HUMAN 1 999.4814 1.26 22021 16331 2 999.480446 500.748 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6.1 3323.8 - 957595 - - - -0.9715 - 1.242 0.12 - 247.1 1 2 0 -0.001 7 0 0 0 4.58E+07 3.63E+07 - - - 0.6137 0.9915 230117_WJC_METTL3_WT_vs_EV_F03.16334.16334.2 0.0996 12-May K.LWYTLDR[166.11].A sp|P00387|NB5R3_HUMAN 1 975.5053 2.02 22023 16334 2 975.505942 488.7599 NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3 5.84 3324.1 - 776829 - - - 0.6202 - 1.259 0.122 - 76.9 1 2 0 0.0006 7 0 0 0 4.78E+07 2.37E+07 - - - 0.6717 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16336.16336.2 0.0169 14-Aug K.VTNLLMLK[136.11].G "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|B4DI28|B4DI28_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|X6R242|X6R242_HUMAN,tr|A0A6Q8PH43|A0A6Q8PH43_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 18 938.5714 1.16 22024 16336 2 938.572364 470.293 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.72 3324.4 - 1.97E+07 - - - 1.0015 - 1.757 0.309 - 195.9 1 2 0 0.0009 8 0 0 0 5.78E+08 4.99E+08 - - - 3.0228 0.9824 230117_WJC_METTL3_WT_vs_EV_F03.16338.16338.2 0.00584 12-Jun R.EAYYWLR[166.11].H sp|P46977|STT3A_HUMAN 1 1009.4897 1.26 22026 16338 2 1009.489416 505.7521 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6.1 3324.6 - 1.45E+06 - - - -0.2685 - 1.399 0.047 - 151.4 1 2 0 -0.0003 7 0 0 0 4.58E+07 3.63E+07 - - - 0.4519 0.9961 230117_WJC_METTL3_WT_vs_EV_F03.16341.16341.2 0.309 12-Sep R.LSAILFK.L "sp|Q9NSV4|DIAP3_HUMAN,sp|Q12830|BPTF_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|J3KSK9|J3KSK9_HUMAN,tr|J3QQQ8|J3QQQ8_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN" 7 790.4953 1.37 22027 16341 2 790.496872 396.2549 Protein diaphanous homolog 3 OS=Homo sapiens OX=9606 GN=DIAPH3 PE=1 SV=4 8.75 3325 - 775192 - - - 2.019 - 1.506 0.123 - 238.8 1 2 0 0.0016 7 0 0 0 1.90E+07 1.38E+07 - - - 1.2464 1 230117_WJC_METTL3_WT_vs_EV_F03.16347.16347.2 2.52E-07 20-Dec R.VGASEAALFLK.K "sp|Q9UBC2|EP15R_HUMAN,tr|M0QX30|M0QX30_HUMAN,tr|K7EJR2|K7EJR2_HUMAN,tr|M0R1V5|M0R1V5_HUMAN,tr|M0R330|M0R330_HUMAN,tr|M0R165|M0R165_HUMAN" 6 1104.6179 0.51 22031 16347 2 1104.626507 553.3162 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 5.97 3325.8 - 494116 - - - 7.7828 - 2.274 0.516 - 373.4 1 2 0 0.0086 11 0 0 0 8.69E+06 1.71E+07 - - - 5.0719 0.9929 230117_WJC_METTL3_WT_vs_EV_F03.16352.16352.2 0.86 14-Jul R.LIGWGQIR[166.11].R "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 951.553 0.86 22034 16352 2 951.554497 476.7838 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 9.75 3326.4 - 1.12E+06 - - - 1.6195 - 1.228 0.144 - 125.5 1 2 0 0.0015 8 0 0 0 6.86E+07 7.99E+07 - - - 0.7235 1 230117_WJC_METTL3_WT_vs_EV_F03.16359.16359.2 7.03E-05 16-Oct R.SLFVVVGDR.G "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 990.5498 0.13 22039 16359 2 990.551123 496.2822 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.55 3327.2 - 678465 - - - 1.3043 - 2.141 0.469 - 290.6 1 2 0 0.0013 9 0 0 0 1.74E+07 1.30E+08 - - - 4.707 0.9671 230117_WJC_METTL3_WT_vs_EV_F03.16361.16361.2 0.0649 20-Oct R.IDALLAVDPPR[166.11].A sp|P50219|MNX1_HUMAN 1 1188.6742 1.96 22041 16361 2 1188.683642 595.3444 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3327.5 - 301787 - - - 7.9492 - 2.181 0.198 - 314.3 1 2 0 0.0094 11 0 0 0 2.20E+07 1.12E+07 - - - 2.61 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16367.16367.2 0.00227 14-Aug K.VTNLLMLK.G "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|B4DI28|B4DI28_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|X6R242|X6R242_HUMAN,tr|A0A6Q8PH43|A0A6Q8PH43_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 18 930.5572 1.16 22046 16367 2 930.559242 466.2859 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.72 3328.2 - 3.59E+07 - - - 2.1686 - 1.819 0.33 - 195.7 1 2 0 0.002 8 0 0 0 5.85E+08 5.03E+08 - - - 3.2822 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.16369.16369.2 0.646 14-Jul R.ALDIPLVK.N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 867.543 1.07 22047 16369 2 867.544549 434.7788 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3328.5 - 2.55E+06 - - - 1.8385 - 1.338 0.224 - 174.4 1 2 0 0.0016 8 0 0 0 3.36E+07 3.13E+07 - - - 1.5731 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16371.16371.2 1.08 14-Sep R.ALDIPLVK[136.11].N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 875.5572 1.08 22049 16371 2 875.559195 438.7859 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3328.6 - 2.40E+06 - - - 2.3311 - 1.813 0.332 - 256.3 1 2 0 0.002 8 0 0 0 3.54E+07 3.28E+07 - - - 3.287 0.9936 230117_WJC_METTL3_WT_vs_EV_F03.16372.16372.2 0.635 12-Jul R.LLLDSLR.K sp|Q10469|MGAT2_HUMAN 1 828.5069 1.09 22050 16372 2 828.507893 415.2607 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 5.84 3328.7 - 2.03E+06 - - - 1.1949 - 1.466 0.073 - 164.9 1 2 0 0.001 7 0 0 0 2.92E+07 2.68E+07 - - - 0.792 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.16383.16383.2 0.0547 12-Jul K.FVSFLGR[166.11].T "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 834.4627 1.26 22059 16383 2 834.464155 418.2386 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 9.75 3329.9 - 3.21E+06 - - - 1.6909 - 1.359 0.27 - 146.9 1 2 0 0.0014 7 0 0 0 2.50E+08 1.99E+08 - - - 2.0067 0.998 230117_WJC_METTL3_WT_vs_EV_F03.16387.16387.2 0.0511 22-Jun R.MPGSVIPPPLVR[166.11].G sp|Q86YP4|P66A_HUMAN 1 1271.7299 2.78 22063 16387 2 1271.732273 636.8722 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.5 3330.4 - 100371 - - - 1.8392 - 1.378 0.255 - 65.6 1 2 0 0.0023 12 0 0 0 3.26E+06 1.17E+06 - - - 1.7673 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.16389.16389.2 0.000597 16-Aug K.GPLMMYISK.M sp|P13639|EF2_HUMAN 1 1038.5242 0.16 22064 16389 2 1038.52671 520.2694 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 3330.7 - 811277 - - - 2.4073 - 1.81 0.438 - 245.9 1 2 0 0.0025 9 0 0 0 5.53E+07 3.40E+08 - - - 3.9918 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.16391.16391.2 0.072 12-Aug K.FVSFLGR.T "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 824.4545 1.14 22065 16391 2 824.455711 413.2345 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 9.75 3330.9 - 3.32E+06 - - - 1.5004 - 1.489 0.337 - 200.5 1 2 0 0.0012 7 0 0 0 2.25E+08 1.97E+08 - - - 2.7911 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.16392.16392.2 0.0588 16-Oct R.SPVYLTVLK[136.11].H "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1026.6205 1.49 22066 16392 2 1026.622371 514.3175 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 8.31 3331 - 307330 - - - 1.839 - 1.846 0.283 - 298.9 1 2 0 0.0019 9 0 0 0 1.58E+07 1.06E+07 - - - 2.9041 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.16397.16397.2 0.00433 16-Aug K.GLIDYETFK.E sp|P15924|DESP_HUMAN 1 1084.5441 1.14 22071 16397 2 1084.548472 543.2793 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3331.7 - 202056 - - - 4.0524 - 1.743 0.316 - 147.6 1 2 0 0.0044 9 0 0 0 5.78E+06 5.07E+06 - - - 2.981 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.16399.16399.2 0.123 16-Aug R.SLFVVVGDR[166.11].G "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 1000.5581 0.72 22072 16399 2 1000.560469 501.2863 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.55 3331.9 - 1.05E+06 - - - 2.3667 - 1.787 0.187 - 260.9 1 2 0 0.0024 9 0 0 0 1.19E+07 1.66E+07 - - - 2.101 1 230117_WJC_METTL3_WT_vs_EV_F03.16400.16400.2 3.46E-05 18-Dec K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 50.9 22073 16400 2 1146.630978 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3332 - 995276 - - - 2.1829 - 2.243 0.515 - 394 1 2 0 0.0025 10 0 0 0 1.57E+08 3.09E+06 - - - 5.0989 1 230117_WJC_METTL3_WT_vs_EV_F03.16404.16404.2 7.25E-07 26-Dec F.LLIGGGTAAFAAAR.S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1287.7299 5.59 22077 16404 2 1287.735518 644.8722 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3332.5 - 146386 - - - 4.3472 - 2.21 0.555 - 426.9 1 1 0 0.0056 14 0 0 0 1.17E+07 2.09E+06 - - - 5.1284 0.9918 230117_WJC_METTL3_WT_vs_EV_F03.16408.16408.2 0.697 14-Jul R.NLLPYSLR[166.11].Y "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 984.5632 0.55 22080 16408 2 984.565074 493.2889 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 8.75 3333 - 302787 - - - 1.9176 - 1.34 0.101 - 102.1 1 2 0 0.0019 8 0 0 0 2.82E+06 5.14E+06 - - - 0.6691 0.9883 230117_WJC_METTL3_WT_vs_EV_F03.16412.16412.2 0.206 16-Jul R.LVLQYAPSA.- "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN" 2 960.528 - 22083 16412 2 960.530838 481.2713 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 5.52 3333.3 - 6.25E+06 - - - 2.9203 - 1.216 0.156 - 127.1 1 2 0 0.0028 9 0 0 0 - - - - - 0.7581 0.95 230117_WJC_METTL3_WT_vs_EV_F03.16413.16413.2 0.00221 12-Jul Q.AAILHLK[136.11].R "sp|Q68DA7|FMN1_HUMAN,sp|Q8NHP7|EXD1_HUMAN,tr|H0YM30|H0YM30_HUMAN,tr|A0A5F9ZHS8|A0A5F9ZHS8_HUMAN" 4 772.5051 1.85 22084 16413 2 772.507116 387.2598 Formin-1 OS=Homo sapiens OX=9606 GN=FMN1 PE=1 SV=3 8.8 3333.4 - 2.34E+06 - - - 2.6628 - 1.504 0.417 - 234.3 1 1 0 0.0021 7 0 0 0 7.92E+07 4.27E+07 - - - 3.4135 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16416.16416.2 0.00019 16-Aug K.GLIDYETFK.E sp|P15924|DESP_HUMAN 1 1084.5441 1.14 22087 16416 2 1084.546251 543.2793 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3333.8 - 589943 - - - 2.0045 - 1.688 0.356 - 155.9 1 2 0 0.0022 9 0 0 0 5.78E+06 5.07E+06 - - - 3.1844 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.16420.16420.2 0.305 20-Jul K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.15 22090 16420 2 1235.764259 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3334.3 - 1.04E+06 - - - 3.3186 - 1.627 0.227 - 163.9 1 2 0 0.0041 11 0 0 0 3.86E+07 3.36E+07 - - - 2.0331 0.971 230117_WJC_METTL3_WT_vs_EV_F03.16421.16421.2 0.0218 26-Oct F.LLIGGGTAAFAAAR[166.11].S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1297.7382 5.59 22091 16421 2 1297.741236 649.8764 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3334.4 - 126341 - - - 2.3472 - 2.085 0.444 - 228 1 1 0 0.003 14 0 0 0 1.17E+07 2.09E+06 - - - 4.1633 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.16422.16422.2 0.116 14-Aug K.VIILSLDR.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 927.5753 2.37 22092 16422 2 927.579076 464.7949 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.81 3334.4 - 1.03E+07 - - - 4.0525 - 1.789 0.35 - 260.7 1 2 0 0.0038 8 0 0 0 1.93E+08 8.15E+07 - - - 3.3792 1 230117_WJC_METTL3_WT_vs_EV_F03.16423.16423.2 4.93E-05 16-Sep K.GPLMMYISK[136.11].M sp|P13639|EF2_HUMAN 1 1046.5384 1.93 22093 16423 2 1046.540951 524.2765 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 3334.5 - 892030 - - - 2.428 - 1.989 0.52 - 339 1 2 0 0.0025 9 0 0 0 4.24E+07 2.20E+07 - - - 4.8703 0.9951 230117_WJC_METTL3_WT_vs_EV_F03.16424.16424.2 0.0279 18-Aug K.AAPEMVSLLK.R "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN,tr|K7EQ99|K7EQ99_HUMAN" 3 1057.5842 1.18 22094 16424 2 1057.588951 529.7994 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 6.05 3334.6 - 1.74E+06 - - - 4.5235 - 1.399 0.33 - 159.4 1 2 0 0.0048 10 0 0 0 4.64E+07 3.94E+07 - - - 2.4141 0.9904 230117_WJC_METTL3_WT_vs_EV_F03.16431.16431.2 2.45 12-Aug K.LPLLLSR.M "sp|P49902|5NTC_HUMAN,sp|O95866|G6B_HUMAN,tr|A0A140T9L8|A0A140T9L8_HUMAN,tr|A0A6Q8PHB5|A0A6Q8PHB5_HUMAN,tr|A0A140T9V1|A0A140T9V1_HUMAN,tr|A0A6Q8PHP0|A0A6Q8PHP0_HUMAN,tr|B7ZLJ5|B7ZLJ5_HUMAN,tr|A0A0G2JJG8|A0A0G2JJG8_HUMAN,tr|F8WDG3|F8WDG3_HUMAN,tr|Q5JUV4|Q5JUV4_HUMAN" 10 810.5327 0.69 22100 16431 2 810.535508 406.2736 Cytosolic purine 5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5C2 PE=1 SV=1 9.75 3335.6 - 401697 - - - 3.4348 - 1.678 0.063 - 300.8 1 2 0 0.0028 7 0 0 0 1.50E+07 2.16E+07 - - - 1.1455 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.16433.16433.2 0.003 14-Aug K.VIFLENYR.V "sp|P06737|PYGL_HUMAN,sp|P11217|PYGM_HUMAN,sp|P11216|PYGB_HUMAN,tr|E9PK47|E9PK47_HUMAN,tr|H0Y4Z6|H0Y4Z6_HUMAN" 5 1052.5655 5.12 22101 16433 2 1052.568466 527.29 "Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL PE=1 SV=4" 5.97 3335.8 - 4.07E+06 - - - 2.8359 - 1.761 0.352 - 271.2 1 2 0 0.003 8 0 0 0 6.07E+07 1.18E+07 - - - 3.3466 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16435.16435.2 0.000732 12-Aug K.YYTLFGR.S sp|P07814|SYEP_HUMAN 1 918.46 1.11 22103 16435 2 918.462387 460.2373 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.59 3335.9 - 3.36E+06 - - - 2.6501 - 1.65 0.397 - 192.4 1 2 0 0.0024 7 0 0 0 1.06E+08 9.55E+07 - - - 3.5592 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.16436.16436.2 0.0193 20-Nov K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.16 22104 16436 2 1245.771399 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3336 - 1.68E+06 - - - 2.3849 - 1.917 0.408 - 334.3 1 2 0 0.003 11 0 0 0 3.53E+07 3.03E+07 - - - 3.814 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.16437.16437.2 0.000238 18-Aug K.AAPEMVSLLK[136.11].R "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN,tr|K7EQ99|K7EQ99_HUMAN" 3 1065.5984 1.21 22105 16437 2 1065.600412 533.8065 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 6.05 3336.1 - 1.43E+06 - - - 1.9191 - 1.556 0.441 - 171.8 1 2 0 0.002 10 0 0 0 4.79E+07 3.96E+07 - - - 3.5317 0.9822 230117_WJC_METTL3_WT_vs_EV_F03.16443.16443.2 0.673 14-May K.VIILSLDR[166.11].S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 937.5836 2.39 22109 16443 2 937.587332 469.7991 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.81 3336.8 - 6.29E+06 - - - 3.9943 - 1.249 0.197 - 63.4 3 2 0 0.0037 8 0 0 0 1.93E+08 8.08E+07 - - - 0.9523 0.9704 230117_WJC_METTL3_WT_vs_EV_F03.16444.16444.2 0.879 14-Aug K.LLELLPGK[136.11].V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 889.5728 2.17 22110 16444 2 889.576567 445.7937 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3336.9 - 1.73E+06 - - - 4.229 - 1.096 0.186 - 150.9 1 2 0 0.0038 8 0 0 0 8.88E+07 4.10E+07 - - - 0.6901 0.8825 230117_WJC_METTL3_WT_vs_EV_F03.16448.16448.2 12.2 12-Jun K.KDEDIAR[166.11].L sp|Q8IVM0|CCD50_HUMAN 1 855.4326 - 22114 16448 2 855.435208 428.7236 Coiled-coil domain-containing protein 50 OS=Homo sapiens OX=9606 GN=CCDC50 PE=1 SV=1 4.56 3337.4 - 641557 - - - 3.0885 - 1.106 0.002 - 117.8 2 2 0 0.0026 7 0 0 0 - - - - - -0.7603 0.999 230117_WJC_METTL3_WT_vs_EV_F03.16455.16455.2 0.00282 12-Aug R.SFDLLVK[136.11].N sp|Q9HB71|CYBP_HUMAN 1 828.4837 2.16 22119 16455 2 828.48551 415.2491 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 5.55 3338.2 - 2.63E+06 - - - 2.239 - 1.5 0.309 - 232 1 2 0 0.0019 7 0 0 0 1.27E+08 5.89E+07 - - - 2.6074 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.16460.16460.2 0.144 14-Sep K.LLELLPGK.V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 881.5586 2.17 22122 16460 2 881.560968 441.7866 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3338.9 - 1.40E+06 - - - 2.6805 - 1.944 0.18 - 270.4 1 2 0 0.0024 8 0 0 0 8.88E+07 4.09E+07 - - - 2.3746 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.16461.16461.2 0.0065 16-Aug K.FGLFTPGSR.L "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 980.508 0.45 22123 16461 2 980.510214 491.2613 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 9.75 3338.9 - 3.17E+06 - - - 2.2927 - 1.371 0.321 - 176.4 1 2 0 0.0022 9 0 0 0 1.50E+08 3.31E+08 - - - 2.3241 0.9946 230117_WJC_METTL3_WT_vs_EV_F03.16463.16463.2 0.0415 16-Jun R.LIPDFPVAR.S sp|Q96S55|WRIP1_HUMAN 1 1026.5862 4.51 22125 16463 2 1026.586912 514.3004 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 5.84 3339.1 - 306825 - - - 0.678 - 1.334 0.151 - 86.4 1 2 0 0.0007 9 0 0 0 1.58E+07 3.51E+06 - - - 0.9898 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.16467.16467.2 0.00729 12-Sep R.SFDLLVK.N sp|Q9HB71|CYBP_HUMAN 1 820.4695 2.16 22127 16467 2 820.472018 411.242 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 5.55 3339.7 - 9.76E+06 - - - 3.1238 - 1.491 0.313 - 277.6 1 2 0 0.0026 7 0 0 0 1.27E+08 5.89E+07 - - - 2.6177 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.16477.16477.2 0.000611 20-Aug R.LVMELSGEMVR.K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1262.6363 2.2 22135 16477 2 1262.6423 632.3254 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3341 - 516916 - - - 4.7686 - 1.617 0.413 - 143.7 1 2 0 0.006 11 0 0 0 1.39E+07 6.33E+06 - - - 3.3896 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.16479.16479.2 0.000603 20-Oct K.NALESYAFNMK.S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1286.5965 36.09 22137 16479 2 1286.600023 644.3055 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3341.2 - 550630 - - - 2.7204 - 2.345 0.428 - 381.5 1 2 0 0.0035 11 0 0 0 2.38E+07 6.59E+05 - - - 4.5067 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.16481.16481.2 0.0076 20-Jul R.LVMELSGEMVR[166.11].K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1272.6445 2.19 22139 16481 2 1272.649306 637.3296 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3341.4 - 226899 - - - 3.7379 - 1.535 0.401 - 134.9 1 2 0 0.0048 11 0 0 0 1.39E+07 6.33E+06 - - - 3.1606 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.16484.16484.2 0.0192 16-Oct K.NAIVVLIPK.Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 965.6274 2.59 22140 16484 2 965.629264 483.821 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3341.8 - 2.88E+06 - - - 1.979 - 1.945 0.479 - 434.2 1 2 0 0.0019 9 0 0 0 1.89E+08 7.29E+07 - - - 4.5029 0.995 230117_WJC_METTL3_WT_vs_EV_F03.16485.16485.2 0.191 12-Jun K.NLFELAR.Q "sp|Q9UN37|VPS4A_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 2 861.4709 4.63 22141 16485 2 861.473016 431.7427 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 6 3341.9 - 1.29E+06 - - - 2.512 - 1.232 0.207 - 151.3 1 2 0 0.0022 7 0 0 0 4.14E+07 8.94E+06 - - - 1.2303 0.9958 230117_WJC_METTL3_WT_vs_EV_F03.16486.16486.2 0.16 20-Sep K.LISSVDPQFLK.L "sp|Q9BVG4|PBDC1_HUMAN,tr|A6NDF3|A6NDF3_HUMAN" 2 1245.6969 9.41 22142 16486 2 1245.701013 623.8557 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 5.84 3342 - 916576 - - - 3.3106 - 1.389 0.25 - 174.9 1 2 0 0.0041 11 0 0 0 3.07E+07 3.27E+06 - - - 1.7751 0.9938 230117_WJC_METTL3_WT_vs_EV_F03.16489.16489.2 0.0185 14-Jul K.SIILEGFK.S sp|O95347|SMC2_HUMAN 1 905.5222 0.27 22145 16489 2 905.526048 453.7684 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 5.72 3342.4 - 154649 - - - 4.2285 - 1.31 0.287 - 115.6 1 2 0 0.0038 8 0 0 0 3.88E+06 1.42E+07 - - - 1.974 0.9085 230117_WJC_METTL3_WT_vs_EV_F03.16490.16490.2 2.45 18-Jun R.LLPQVDSVLK.S "sp|Q9C0B9|ZCHC2_HUMAN,tr|K7EKB8|K7EKB8_HUMAN,tr|K7ESN2|K7ESN2_HUMAN" 3 1110.6649 5.67 22146 16490 2 1110.670874 556.3397 Zinc finger CCHC domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZCCHC2 PE=1 SV=6 5.84 3342.5 - 94697.2 - - - 5.4139 - 1.146 0.136 - 60.8 1 2 0 0.006 10 0 0 0 1.71E+06 3.01E+05 - - - 0.424 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.16495.16495.2 0.0372 12-Aug K.VFDLLNR.K "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|H0Y8H2|H0Y8H2_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 875.4865 1.32 22149 16495 2 875.487751 438.7505 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 5.81 3343 - 1.53E+06 - - - 1.4266 - 1.556 0.224 - 243.8 1 2 0 0.0012 7 0 0 0 2.22E+07 1.68E+07 - - - 2.0959 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.16503.16503.2 0.0944 16-Aug R.LTQEVLLLR.E "sp|Q5VU43|MYOME_HUMAN,tr|E9PQG4|E9PQG4_HUMAN,tr|A0A087WX83|A0A087WX83_HUMAN,tr|A0A075B749|A0A075B749_HUMAN" 4 1083.6652 2.22 22155 16503 2 1083.667234 542.8399 Myomegalin OS=Homo sapiens OX=9606 GN=PDE4DIP PE=1 SV=3 6 3344 - 325331 - - - 1.8816 - 1.851 0.266 - 218.6 1 2 0 0.002 9 0 0 0 9.28E+06 4.18E+06 - - - 2.7864 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.16506.16506.2 0.00804 16-Nov R.LLQSLLDTR.C sp|Q13045|FLII_HUMAN 1 1057.6132 1.35 22156 16506 2 1057.617547 529.8139 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3344.4 - 641735 - - - 4.149 - 1.959 0.331 - 394.2 1 2 0 0.0044 9 0 0 0 1.67E+07 1.24E+07 - - - 3.4298 0.996 230117_WJC_METTL3_WT_vs_EV_F03.16509.16509.2 0.0991 20-Jul R.VPLIGSLPEAR[166.11].L "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN,tr|K7EQG1|K7EQG1_HUMAN" 3 1160.6793 1.12 22159 16509 2 1160.678381 581.3469 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 5.97 3344.8 - 190565 - - - -0.7737 - 1.661 0.197 - 123.4 1 2 0 -0.0009 11 0 0 0 2.37E+06 2.11E+06 - - - 1.8685 0.9927 230117_WJC_METTL3_WT_vs_EV_F03.16514.16514.2 0.147 16-Jun K.VYLGDIPLK[136.11].T "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1024.6048 1.71 22162 16514 2 1024.60361 513.3097 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.81 3345.4 - 2.48E+06 - - - -1.1936 - 1.217 0.264 - 57.1 1 2 0 -0.0012 9 0 0 0 4.10E+07 2.40E+07 - - - 1.5587 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.16523.16523.2 0.0673 12-Jun K.LFDFPGR.G sp|Q9P258|RCC2_HUMAN 1 850.4337 2.42 22170 16523 2 850.43334 426.2241 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.84 3346.5 - 1.94E+06 - - - -0.468 - 1.399 0.321 - 137.1 1 2 0 -0.0004 7 0 0 0 2.11E+08 8.72E+07 - - - 2.4756 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.16525.16525.2 0.0417 14-Nov R.IGVDLIMK.T "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 887.515 0.96 22172 16525 2 887.513834 444.7648 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.84 3346.8 - 1.76E+06 - - - -1.3419 - 1.48 0.279 - 260.3 1 2 0 -0.0012 8 0 0 0 3.09E+07 3.23E+07 - - - 2.2837 0.9814 230117_WJC_METTL3_WT_vs_EV_F03.16547.16547.2 0.202 12-Jul R.DLIDYVR.Y "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 892.4654 2.5 22184 16547 2 892.464129 447.24 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.21 3349.4 - 1.45E+06 - - - -1.46 - 1.282 0.152 - 202 1 2 0 -0.0013 7 0 0 0 5.57E+07 2.23E+07 - - - 0.9504 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.16552.16552.2 2.65 14-Aug R.DAFLTLAR.D "sp|Q92793|CBP_HUMAN,sp|Q09472|EP300_HUMAN,tr|A0A669KB12|A0A669KB12_HUMAN" 3 905.4971 2.23 22186 16552 2 905.498989 453.7558 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 5.84 3350.1 - 0 - - - 2.1226 - 1.763 0.222 - 248.8 1 2 0 0.0019 8 0 0 0 2.99E+07 1.34E+07 - - - 2.3902 0.9605 230117_WJC_METTL3_WT_vs_EV_F03.16591.16591.2 0.258 14-Aug K.GYGFGLIK.L "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 853.4698 1.37 22192 16591 2 853.467455 427.7422 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 3356.1 - 8.55E+06 - - - -2.7359 - 1.133 0.211 - 170.5 1 2 0 -0.0023 8 0 0 0 1.01E+09 7.40E+08 - - - 0.9753 1 230117_WJC_METTL3_WT_vs_EV_F03.16592.16592.2 2.95E-07 13/22 K.VFGAAPLENVVR.K "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 1270.7034 6.38 22193 16592 2 1270.702166 636.359 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 5.97 3356.2 - 3.70E+06 - - - -0.9483 - 2.45 0.514 - 563.2 1 2 0 -0.0012 12 0 0 0 1.32E+08 2.07E+07 - - - 5.1948 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.16593.16593.2 0.00102 15/24 K.VLIIGGGDGGVLR.E "sp|P19623|SPEE_HUMAN,tr|K7ESL0|K7ESL0_HUMAN" 2 1224.719 12.99 22194 16593 2 1224.716555 613.3668 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.81 3356.3 - 3.62E+06 - - - -2.0135 - 2.275 0.408 - 693.4 1 2 0 -0.0025 13 0 0 0 1.58E+08 1.22E+07 - - - 4.1633 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16613.16613.2 0.000968 18-Oct K.IFFAGDTIPK.S "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 5 1107.5964 2.21 22198 16613 2 1107.596034 554.8055 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.84 3359.2 - 2.90E+06 - - - -0.3729 - 1.959 0.412 - 254.7 1 2 0 -0.0004 10 0 0 0 1.32E+08 5.99E+07 - - - 3.9609 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16618.16618.2 3.8 18-Oct R.LYLINSPVVR.A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1172.6917 1.61 22199 16618 2 1172.693767 587.3531 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3360 - 4.04E+06 - - - 1.7251 - 2.117 0.249 - 433.4 1 2 0 0.002 10 0 0 0 6.10E+08 3.78E+08 - - - 2.973 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.16621.16621.2 7.79E-05 18-Sep R.LYLINSPVVR[166.11].A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1182.7 1.61 22200 16621 2 1182.698407 592.3573 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3360.4 - 2.33E+06 - - - -1.3588 - 2.002 0.27 - 306.2 1 2 0 -0.0016 10 0 0 0 6.10E+08 3.78E+08 - - - 2.9723 0.9869 230117_WJC_METTL3_WT_vs_EV_F03.16625.16625.2 0.187 14-Jun R.VAFTLLEK.V "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 4 919.5379 9.57 22202 16625 2 919.536359 460.7762 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 5.97 3360.8 - 1.49E+06 - - - -1.6421 - 1.463 0.171 - 92.6 2 2 0 -0.0015 8 0 0 0 1.19E+08 1.24E+07 - - - 1.3166 0.9951 230117_WJC_METTL3_WT_vs_EV_F03.16627.16627.2 0.881 14-Sep K.IPLGLDLK.N "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 867.543 1.81 22203 16627 2 867.544386 434.7788 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.84 3361.1 - 3.06E+06 - - - 1.6506 - 1.682 0.054 - 281.6 1 2 0 0.0014 8 0 0 0 1.84E+08 1.01E+08 - - - 1.0076 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.16635.16635.2 0.0479 14-Sep R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 9982.88 22206 16635 2 1000.56082 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3362.1 - 7.05E+09 - - - 1.4862 - 2.073 0.317 - 271 1 2 0 0.0015 8 0 0 0 9.06E+11 9.08E+07 - - - 3.5805 1 230117_WJC_METTL3_WT_vs_EV_F03.16636.16636.2 0.0012 18-Dec R.VAAAVDLIIK.S "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1011.6328 1.8 22207 16636 2 1011.626665 506.8237 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3362.2 - 4.25E+06 - - - -6.0961 - 2.504 0.462 - 430 1 2 0 -0.0062 10 0 0 0 1.86E+08 1.03E+08 - - - 5.0135 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.16640.16640.2 7.59E-05 18-Aug K.IFFAGDTIPK[136.11].S "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 5 1115.6106 2.26 22208 16640 2 1115.610754 558.8126 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.84 3362.8 - 2.11E+06 - - - 0.0959 - 1.699 0.451 - 84.7 1 2 0 0.0001 10 0 0 0 1.35E+08 5.99E+07 - - - 3.8516 1 230117_WJC_METTL3_WT_vs_EV_F03.16642.16642.2 2.32E-07 22-Dec R.GYISPYFINTSK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1388.6976 2.73 22209 16642 2 1388.692984 695.3561 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3363 - 1.49E+06 - - - -3.3362 - 2.408 0.499 - 524.1 1 2 0 -0.0046 12 0 0 0 8.70E+07 3.18E+07 - - - 5.0374 1 230117_WJC_METTL3_WT_vs_EV_F03.16644.16644.2 0.00166 18-Dec R.YGLAAAVFTR.D sp|P30837|AL1B1_HUMAN 1 1067.5764 2.96 22210 16644 2 1067.574345 534.7955 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 8.75 3363.2 - 1.97E+06 - - - -1.9062 - 2.42 0.443 - 436.9 1 2 0 -0.002 10 0 0 0 9.04E+07 3.05E+07 - - - 4.7792 0.9939 230117_WJC_METTL3_WT_vs_EV_F03.16650.16650.2 0.00201 18-Nov R.GTPLISPLIK.W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1037.6485 1.68 22211 16650 2 1037.644452 519.8315 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3364.1 - 2.46E+06 - - - -3.8838 - 1.82 0.407 - 481 1 2 0 -0.004 10 0 0 0 2.75E+08 1.63E+08 - - - 3.7174 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.16652.16652.2 0.000298 18-Sep R.GTPLISPLIK[136.11].W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1045.6627 1.68 22212 16652 2 1045.660028 523.8386 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3364.3 - 1.89E+06 - - - -2.5381 - 1.724 0.47 - 254.1 1 2 0 -0.0027 10 0 0 0 2.75E+08 1.63E+08 - - - 4.0319 0.998 230117_WJC_METTL3_WT_vs_EV_F03.16660.16660.2 0.224 16-Jul K.GSLLPTSPR[166.11].L "tr|H7C179|H7C179_HUMAN,tr|H7C128|H7C128_HUMAN,tr|H7C127|H7C127_HUMAN" 3 936.5268 1.44 22215 16660 2 936.527784 469.2707 Bromodomain-containing protein 8 (Fragment) OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=1 9.75 3365.4 - 1.80E+06 - - - 1.0496 - 1.389 0.255 - 95.7 2 2 0 0.001 9 0 0 0 2.83E+08 1.97E+08 - - - 1.7403 0.9939 230117_WJC_METTL3_WT_vs_EV_F03.16662.16662.2 0.413 16-Aug K.GSLLPTSPR.L "tr|H7C179|H7C179_HUMAN,tr|H7C128|H7C128_HUMAN,tr|H7C127|H7C127_HUMAN" 3 926.5185 1.45 22216 16662 2 926.519652 464.2665 Bromodomain-containing protein 8 (Fragment) OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=1 9.75 3365.6 - 4.01E+06 - - - 1.2099 - 1.42 0.105 - 178.8 1 2 0 0.0011 9 0 0 0 2.83E+08 1.96E+08 - - - 0.8306 0.998 230117_WJC_METTL3_WT_vs_EV_F03.16668.16668.2 0.0116 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.09 22219 16668 2 1235.758372 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3366.3 - 988243 - - - -1.4453 - 1.758 0.34 - 253.5 1 2 0 -0.0018 11 0 0 0 1.62E+08 1.48E+08 - - - 3.0779 0.9958 230117_WJC_METTL3_WT_vs_EV_F03.16672.16672.2 0.0358 12-Jul K.FTVPMLK[136.11].E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 842.4815 0.88 22221 16672 2 842.480123 422.248 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3366.9 - 1.22E+06 - - - -1.6902 - 1.584 0.255 - 173.9 1 2 0 -0.0014 7 0 0 0 1.44E+08 1.63E+08 - - - 2.3814 1 230117_WJC_METTL3_WT_vs_EV_F03.16678.16678.2 0.000625 13/20 R.FGGLVLSPVGK.Q sp|Q9UJK0|TSR3_HUMAN 1 1072.6281 1.27 22225 16678 2 1072.627409 537.3213 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.75 3367.6 - 1.96E+06 - - - -0.6265 - 2.52 0.556 - 556.4 1 2 0 -0.0007 11 0 0 0 6.87E+07 5.41E+07 - - - 5.6477 0.9934 230117_WJC_METTL3_WT_vs_EV_F03.16683.16683.2 0.181 12-Jul K.FTVPMLK.E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 834.4673 0.89 22226 16683 2 834.467269 418.2409 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3368.4 - 1.98E+06 - - - -0.0935 - 1.274 0.175 - 167.9 1 2 0 -0.0001 7 0 0 0 1.45E+08 1.63E+08 - - - 1.1008 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.16685.16685.2 0.0212 16-Oct K.AAYVLFYQR.R "sp|Q13107|UBP4_HUMAN,sp|Q9Y4E8|UBP15_HUMAN,sp|P51784|UBP11_HUMAN,tr|G5E9A6|G5E9A6_HUMAN" 4 1129.592 5.7 22228 16685 2 1129.594624 565.8033 Ubiquitin carboxyl-terminal hydrolase 4 OS=Homo sapiens OX=9606 GN=USP4 PE=1 SV=3 8.63 3368.6 - 1.32E+06 - - - 2.2964 - 1.745 0.383 - 342.6 1 2 0 0.0026 9 0 0 0 1.81E+07 3.17E+06 - - - 3.4797 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.16687.16687.2 0.164 20-Oct K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.09 22230 16687 2 1245.767357 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3368.9 - 1.31E+06 - - - -0.8597 - 1.96 0.378 - 286.2 1 2 0 -0.0011 11 0 0 0 1.65E+08 1.51E+08 - - - 3.653 1 230117_WJC_METTL3_WT_vs_EV_F03.16693.16693.2 0.000331 13/20 R.FGGLVLSPVGK[136.11].Q sp|Q9UJK0|TSR3_HUMAN 1 1080.6423 1.3 22234 16693 2 1080.645351 541.3284 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.75 3369.6 - 2.80E+06 - - - 2.8409 - 2.394 0.469 - 505.8 1 2 0 0.0031 11 0 0 0 6.85E+07 5.26E+07 - - - 4.8656 0.9708 230117_WJC_METTL3_WT_vs_EV_F03.16694.16694.2 0.811 12-May K.LILQPWK[136.11].D sp|Q9UBB9|TFP11_HUMAN 1 904.5626 1.1 22235 16694 2 904.563735 453.2886 Tuftelin-interacting protein 11 OS=Homo sapiens OX=9606 GN=TFIP11 PE=1 SV=1 8.75 3369.7 - 1.22E+06 - - - 1.2835 - 1.029 0.084 - 64.6 1 2 0 0.0012 7 0 0 0 1.50E+07 1.37E+07 - - - -0.2484 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.16697.16697.2 0.183 12-Sep R.FGIEIIK.W "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 818.4902 1.7 22236 16697 2 818.492155 410.2524 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 6 3370.1 - 1.32E+06 - - - 2.3995 - 1.871 0.118 - 233.2 1 2 0 0.002 7 0 0 0 5.74E+07 3.39E+07 - - - 1.8969 0.9962 230117_WJC_METTL3_WT_vs_EV_F03.16699.16699.2 1.72 12-Jul R.ILLQYLK.Q "sp|Q9P0U3|SENP1_HUMAN,sp|Q9NVH2|INT7_HUMAN" 2 889.5637 4.3 22237 16699 2 889.566038 445.7891 Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2 8.59 3370.3 - 1.98E+06 - - - 2.6395 - 1.312 0.218 - 148.8 1 2 0 0.0023 7 0 0 0 3.54E+07 8.25E+06 - - - 1.5108 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.16705.16705.2 0.128 16-Oct K.LLC[160.03]GLLAER[166.11].L sp|P14174|MIF_HUMAN 1 1053.588 0.91 22240 16705 2 1053.586908 527.8013 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3371 - 3.50E+06 - - - -1.0564 - 2.054 0.28 - 337.4 1 2 0 -0.0011 9 0 0 0 9.05E+08 9.99E+08 - - - 3.1911 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.16706.16706.2 0.0157 16-Sep R.GLFTGLTPR[166.11].L "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 970.5475 1.24 22241 16706 2 970.547378 486.281 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3371.1 - 533565 - - - -0.1628 - 1.947 0.327 - 222.2 1 2 0 -0.0002 9 0 0 0 6.09E+07 4.91E+07 - - - 3.3838 0.9212 230117_WJC_METTL3_WT_vs_EV_F03.16708.16708.2 0.462 12-Jun R.FVAELWK[136.11].D sp|P35580|MYH10_HUMAN 1 899.4996 0.75 22243 16708 2 899.497028 450.7571 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3371.3 - 1.13E+06 - - - -2.9038 - 1.004 0.199 - 101.7 1 2 0 -0.0026 7 0 0 0 8.72E+07 1.16E+08 - - - 0.5226 0.9807 230117_WJC_METTL3_WT_vs_EV_F03.16709.16709.2 0.0661 16-Jul R.YVANLFPYK.G "sp|Q15181|IPYR_HUMAN,sp|Q9H2U2|IPYR2_HUMAN,tr|D6RGV9|D6RGV9_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN,tr|D6RGI1|D6RGI1_HUMAN,tr|H0YAK2|H0YAK2_HUMAN" 7 1113.5859 2.63 22244 16709 2 1113.581965 557.8002 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 8.5 3371.4 - 900915 - - - -3.5175 - 1.232 0.319 - 84.2 1 2 0 -0.0039 9 0 0 0 9.13E+07 3.47E+07 - - - 1.9995 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.16710.16710.2 0.525 16-Aug R.GLFTGLTPR.L "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 960.5393 1.24 22245 16710 2 960.539343 481.2769 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3371.6 - 708024 - - - 0.0802 - 1.596 0.229 - 162 1 2 0 0.0001 9 0 0 0 6.09E+07 4.91E+07 - - - 2.0849 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.16714.16714.2 0.0218 16-Jul K.LLC[160.03]GLLAER.L sp|P14174|MIF_HUMAN 1 1043.5798 0.9 22247 16714 2 1043.579643 522.7972 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3372.1 - 6.60E+06 - - - -0.1035 - 1.747 0.224 - 117.2 2 2 0 -0.0001 9 0 0 0 9.06E+08 1.00E+09 - - - 2.175 1 230117_WJC_METTL3_WT_vs_EV_F03.16715.16715.2 0.000211 18-Nov K.VYVIGSFVDK.S sp|Q7L0Y3|TM10C_HUMAN 1 1125.607 0.7 22248 16715 2 1125.61388 563.8108 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3372.2 - 638824 - - - 6.1025 - 2.419 0.468 - 404.9 1 2 0 0.0069 10 0 0 0 3.76E+07 5.34E+07 - - - 4.9612 1 230117_WJC_METTL3_WT_vs_EV_F03.16716.16716.2 0.000203 18-Nov K.VYVIGSFVDK[136.11].S sp|Q7L0Y3|TM10C_HUMAN 1 1133.6212 0.7 22249 16716 2 1133.622943 567.8179 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3372.4 - 1.30E+06 - - - 1.5278 - 2.126 0.512 - 346.6 1 2 0 0.0017 10 0 0 0 3.76E+07 5.34E+07 - - - 4.9274 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.16721.16721.2 0.0495 12-Jun K.LMIWDTR.S "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 933.4742 1.23 22252 16721 2 933.475664 467.7444 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3373 - 6.99E+06 - - - 1.5437 - 1.35 0.314 - 216.5 1 2 0 0.0014 7 0 0 0 2.93E+08 2.39E+08 - - - 2.3106 0.9969 230117_WJC_METTL3_WT_vs_EV_F03.16722.16722.2 0.0431 12-Jun R.FVAELWK.D sp|P35580|MYH10_HUMAN 1 891.4854 0.76 22253 16722 2 891.486738 446.75 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3373.1 - 2.66E+06 - - - 1.456 - 1.282 0.206 - 118.1 1 2 0 0.0013 7 0 0 0 8.75E+07 1.16E+08 - - - 1.3492 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.16723.16723.2 0.00621 18-Sep K.APGLGLVLER.V "sp|Q9Y606|TRUA_HUMAN,tr|G8JLB3|G8JLB3_HUMAN,tr|F5H1S9|F5H1S9_HUMAN" 3 1023.6077 1.78 22254 16723 2 1023.608986 512.8111 tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3 6.05 3373.1 - 2.61E+06 - - - 1.2759 - 1.617 0.367 - 164 1 2 0 0.0013 10 0 0 0 5.14E+07 2.90E+07 - - - 3.0927 0.9332 230117_WJC_METTL3_WT_vs_EV_F03.16724.16724.2 15.4 12-Jun R.FLPLNIR[166.11].N "sp|Q7Z6E9|RBBP6_HUMAN,tr|H3BSK8|H3BSK8_HUMAN,tr|A0A2R8Y880|A0A2R8Y880_HUMAN" 3 881.5362 1.03 22255 16724 2 881.537266 441.7754 E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1 9.75 3373.2 - 1.99E+06 - - - 1.1605 - 1.021 0.044 - 113.7 3 2 0 0.001 7 0 0 0 5.09E+07 4.93E+07 - - - -0.7816 0.9458 230117_WJC_METTL3_WT_vs_EV_F03.16725.16725.2 8.93 12-May K.IFINLPR.S "sp|O43396|TXNL1_HUMAN,tr|K7ER96|K7ER96_HUMAN" 2 871.528 0.79 22256 16725 2 871.529136 436.7713 Thioredoxin-like protein 1 OS=Homo sapiens OX=9606 GN=TXNL1 PE=1 SV=3 9.75 3373.3 - 1.82E+06 - - - 1.3344 - 1.179 0 - 72.9 3 2 0 0.0012 7 0 0 0 5.24E+07 6.61E+07 - - - -0.6507 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.16727.16727.2 0.000575 22-Oct R.VLIGNVQPGILR.F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1277.782 3.36 22258 16727 2 1277.785675 639.8983 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3373.5 - 472247 - - - 2.9105 - 2.008 0.437 - 388.4 1 2 0 0.0037 12 0 0 0 6.41E+06 1.91E+06 - - - 4.1018 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.16735.16735.2 0.00944 12-Jul R.GFELTFK[136.11].T "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 848.4524 1.36 22264 16735 2 848.455391 425.2335 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3374.4 - 780964 - - - 3.5783 - 1.468 0.289 - 166.9 1 2 0 0.003 7 0 0 0 6.38E+07 4.67E+07 - - - 2.391 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.16738.16738.2 0.0499 14-Jul K.LGPLAFYK[136.11].G "sp|Q9UBX3|DIC_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 915.5309 1.86 22265 16738 2 915.533913 458.7727 Mitochondrial dicarboxylate carrier OS=Homo sapiens OX=9606 GN=SLC25A10 PE=1 SV=2 8.59 3374.8 - 1.25E+06 - - - 3.2473 - 1.279 0.291 - 112.4 1 2 0 0.003 8 0 0 0 5.85E+07 3.14E+07 - - - 1.9316 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16743.16743.2 0.0029 22-Oct R.VLIGNVQPGILR.F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1277.782 3.36 22270 16743 2 1277.783234 639.8983 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3375.3 - 368911 - - - 1.0002 - 2.117 0.273 - 369 1 2 0 0.0013 12 0 0 0 6.41E+06 1.91E+06 - - - 3.0304 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.16746.16746.2 0.678 12-Jul R.LTLLQLK.G sp|Q8NHP8|PLBL2_HUMAN 1 827.548 1.13 22271 16746 2 827.549683 414.7813 Putative phospholipase B-like 2 OS=Homo sapiens OX=9606 GN=PLBD2 PE=1 SV=2 8.75 3375.7 - 970531 - - - 1.9854 - 1.53 0.16 - 107.7 1 2 0 0.0016 7 0 0 0 2.38E+07 2.11E+07 - - - 1.5697 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.16750.16750.2 0.00135 16-Oct K.FLGELYNYR[166.11].M sp|Q9HAU5|RENT2_HUMAN 1 1183.5901 0.8 22275 16750 2 1183.590971 592.8023 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 6 3376.3 - 583841 - - - 0.7114 - 1.816 0.358 - 298.2 1 2 0 0.0008 9 0 0 0 9.67E+06 1.21E+07 - - - 3.411 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.16758.16758.2 0.00931 18-Oct R.FGVITEVDIK.R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1119.6176 1.1 22281 16758 2 1119.619299 560.8161 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 4.37 3377.1 - 1.41E+06 - - - 1.5389 - 2.121 0.373 - 357.4 1 2 0 0.0017 10 0 0 0 2.41E+07 2.19E+07 - - - 3.8942 1 230117_WJC_METTL3_WT_vs_EV_F03.16760.16760.2 4.51E-05 20-Dec R.ALDEGDIALLK[136.11].T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1164.6482 2.81 22283 16760 2 1164.646943 583.3314 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 3377.3 - 387855 - - - -1.0398 - 2.489 0.494 - 300.2 1 2 0 -0.0012 11 0 0 0 1.72E+07 6.12E+06 - - - 5.1562 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.16763.16763.2 0.595 14-Aug R.ILELDQFK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1012.5684 1.05 22284 16763 2 1012.569819 507.2915 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3377.7 - 9.61E+06 - - - 1.355 - 1.494 0.262 - 143.6 1 2 0 0.0014 8 0 0 0 2.68E+08 2.55E+08 - - - 2.1865 0.9965 230117_WJC_METTL3_WT_vs_EV_F03.16764.16764.2 0.0686 14-Jul R.LYEFYLSK.C "sp|Q5VZL5|ZMYM4_HUMAN,tr|H7C1I7|H7C1I7_HUMAN" 2 1061.5433 1.36 22285 16764 2 1061.543447 531.779 Zinc finger MYM-type protein 4 OS=Homo sapiens OX=9606 GN=ZMYM4 PE=1 SV=1 6 3377.8 - 1.06E+06 - - - 0.0933 - 1.247 0.247 - 111.6 1 2 0 0.0001 8 0 0 0 2.32E+07 1.71E+07 - - - 1.5311 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.16765.16765.2 2.37 12-Aug K.LDDLFLK.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 862.48 0.94 22286 16765 2 862.481117 432.2473 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3377.8 - 5.88E+06 - - - 1.2719 - 1.753 0.052 - 224.2 1 2 0 0.0011 7 0 0 0 1.22E+08 1.30E+08 - - - 1.2033 0.997 230117_WJC_METTL3_WT_vs_EV_F03.16767.16767.2 0.126 16-Jun R.VLIFSQMTK[136.11].M "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|F2Z2R5|F2Z2R5_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|A0A5F9ZHX5|A0A5F9ZHX5_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|K7EMY3|K7EMY3_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 25 1073.6035 1.88 22288 16767 2 1073.602725 537.809 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.72 3378 - 905286 - - - -0.6781 - 1.345 0.293 - 74.4 1 2 0 -0.0007 9 0 0 0 1.81E+07 9.62E+06 - - - 2.0624 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.16771.16771.2 0.00463 12-Jul K.LMIWDTR[166.11].S "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 943.4825 1.71 22291 16771 2 943.48436 472.7485 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3378.4 - 6.90E+06 - - - 1.9788 - 1.453 0.351 - 282.7 1 2 0 0.0019 7 0 0 0 2.88E+08 1.69E+08 - - - 2.8168 0.8757 230117_WJC_METTL3_WT_vs_EV_F03.16776.16776.2 0.0855 16-Jun K.IDPEAFITR[166.11].H sp|Q92616|GCN1_HUMAN 1 1070.5636 0.72 22295 16776 2 1070.56065 536.2891 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3378.9 - 1.15E+06 - - - -2.7369 - 1.246 0.077 - 76.5 2 2 0 -0.0029 9 0 0 0 1.33E+07 1.85E+07 - - - 0.1106 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16782.16782.2 0.00505 18-Sep R.FGVITEVDIK[136.11].R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1127.6318 1.12 22299 16782 2 1127.635126 564.8232 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 4.37 3379.5 - 1.30E+06 - - - 2.9708 - 1.929 0.389 - 232 1 2 0 0.0034 10 0 0 0 2.46E+07 2.19E+07 - - - 3.747 0.9615 230117_WJC_METTL3_WT_vs_EV_F03.16784.16784.2 0.537 12-Jun R.LYEFIVR[166.11].H sp|Q13472|TOP3A_HUMAN 1 948.5308 0.92 22301 16784 2 948.532791 475.2727 DNA topoisomerase 3-alpha OS=Homo sapiens OX=9606 GN=TOP3A PE=1 SV=1 6 3379.7 - 2.24E+06 - - - 2.0748 - 1.186 0.01 - 104.5 1 2 0 0.002 7 0 0 0 2.89E+07 3.15E+07 - - - -0.3452 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.16786.16786.2 0.113 20-Oct K.LLAAFPGVTPR.V "sp|Q9Y2I1|NISCH_HUMAN,tr|C9J715|C9J715_HUMAN" 2 1140.6655 1.27 22303 16786 2 1140.665798 571.34 Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3 9.75 3379.9 - 464177 - - - 0.2358 - 1.687 0.214 - 252.7 1 2 0 0.0003 11 0 0 0 9.65E+06 7.58E+06 - - - 2.0362 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.16787.16787.2 0.00182 18-Jul K.IVAFENAFER.L sp|O60763|USO1_HUMAN 1 1194.6033 0.84 22304 16787 2 1194.605714 598.3089 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 3380 - 372667 - - - 2.0015 - 1.552 0.183 - 105.6 1 2 0 0.0024 10 0 0 0 4.79E+06 5.69E+06 - - - 1.6188 0.9947 230117_WJC_METTL3_WT_vs_EV_F03.16790.16790.2 0.076 14-Jun K.LEPDILLR[166.11].A "sp|Q01433|AMPD2_HUMAN,tr|A0A7P0TB79|A0A7P0TB79_HUMAN,tr|A0A590UK85|A0A590UK85_HUMAN,tr|A0A5F9UK94|A0A5F9UK94_HUMAN,tr|E9PJF6|E9PJF6_HUMAN,tr|A0A590UJX5|A0A590UJX5_HUMAN,tr|H0Y360|H0Y360_HUMAN,tr|A0A7P0Z4H6|A0A7P0Z4H6_HUMAN,tr|E9PIJ1|E9PIJ1_HUMAN,tr|H0YF16|H0YF16_HUMAN,tr|A0A804CCZ3|A0A804CCZ3_HUMAN" 11 977.5785 2.78 22307 16790 2 977.577999 489.7965 AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2 4.37 3380.4 - 252660 - - - -0.5145 - 1.258 0.253 - 74.2 2 2 0 -0.0005 8 0 0 0 1.39E+07 4.99E+06 - - - 1.4673 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16793.16793.2 0.0114 14-Sep K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 0.79 22308 16793 2 988.573251 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3380.8 - 4.37E+06 - - - 2.716 - 1.836 0.381 - 369.9 1 2 0 0.0027 8 0 0 0 2.99E+09 3.78E+09 - - - 3.6867 0.999 230117_WJC_METTL3_WT_vs_EV_F03.16795.16795.2 0.00214 14-Sep R.VWDISGLR[166.11].K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 954.5162 2.86 22310 16795 2 954.518171 478.2654 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3380.9 - 1.07E+06 - - - 2.0272 - 1.899 0.202 - 310.7 1 2 0 0.0019 8 0 0 0 5.06E+07 1.77E+07 - - - 2.4666 0.9919 230117_WJC_METTL3_WT_vs_EV_F03.16797.16797.2 0.0638 20-Jul R.LYPEGLAQLAR[166.11].A "sp|P61421|VA0D1_HUMAN,tr|J3QL14|J3QL14_HUMAN,tr|F5GYQ1|F5GYQ1_HUMAN,tr|R4GN72|R4GN72_HUMAN" 4 1239.6851 1.22 22312 16797 2 1239.688238 620.8498 V-type proton ATPase subunit d 1 OS=Homo sapiens OX=9606 GN=ATP6V0D1 PE=1 SV=1 6 3381.1 - 178031 - - - 2.5377 - 1.378 0.13 - 109.1 1 2 0 0.0031 11 0 0 0 9.77E+06 8.02E+06 - - - 0.8676 0.9607 230117_WJC_METTL3_WT_vs_EV_F03.16800.16800.2 0.212 12-May K.FIDPFC[160.03]K.L sp|Q14684|RRP1B_HUMAN 1 925.4368 15.38 22313 16800 2 925.43886 463.7257 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.83 3381.5 - 1.14E+06 - - - 2.253 - 0.949 0.11 - 76.1 1 2 0 0.0021 7 0 0 0 1.97E+07 1.28E+06 - - - -0.3131 0.9718 230117_WJC_METTL3_WT_vs_EV_F03.16803.16803.2 0.00462 14-Jul R.VWDISGLR.K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 944.508 2.84 22316 16803 2 944.514428 473.2613 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3381.7 - 4.57E+06 - - - 6.8417 - 1.654 0.22 - 210 1 2 0 0.0065 8 0 0 0 5.00E+07 1.76E+07 - - - 2.1815 0.959 230117_WJC_METTL3_WT_vs_EV_F03.16804.16804.2 0.0335 20-Oct K.LLAAFPGVTPR[166.11].V "sp|Q9Y2I1|NISCH_HUMAN,tr|C9J715|C9J715_HUMAN" 2 1150.6738 1.24 22317 16804 2 1150.666678 576.3442 Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3 9.75 3381.8 - 3.65E+06 - - - -6.1885 - 1.991 0.279 - 222 1 2 0 -0.0071 11 0 0 0 9.38E+06 7.58E+06 - - - 2.9624 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.16823.16823.2 0.193 14-Aug K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 0.79 22334 16823 2 998.578879 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3384 - 1.85E+08 - - - 0.0431 - 1.754 0.291 - 295 1 2 0 0 8 0 0 0 2.99E+09 3.78E+09 - - - 2.885 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.16825.16825.2 0.000124 16-Aug R.ATLNAFLYR[166.11].T "sp|Q5T2N8|ATD3C_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 3 1077.5847 1.31 22336 16825 2 1077.586372 539.7996 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 8.79 3384.2 - 2.07E+06 - - - 1.598 - 1.964 0.413 - 254.7 1 2 0 0.0017 9 0 0 0 3.72E+07 2.84E+07 - - - 4.0436 0.9924 230117_WJC_METTL3_WT_vs_EV_F03.16826.16826.2 0.0482 12-Jul R.IPTAWFR.E "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN" 2 889.481 1.57 22337 16826 2 889.48031 445.7478 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 9.75 3384.3 - 2.01E+06 - - - -0.8016 - 1.288 0.2 - 167 1 2 0 -0.0007 7 0 0 0 8.77E+07 5.57E+07 - - - 1.3199 0.9956 230117_WJC_METTL3_WT_vs_EV_F03.16828.16828.2 0.822 14-Jun R.DILLQGLK[136.11].A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 906.563 0.92 22339 16828 2 906.564348 454.2888 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3384.4 - 1.69E+06 - - - 1.5222 - 1.316 0.163 - 109 1 2 0 0.0014 8 0 0 0 1.24E+07 1.34E+07 - - - 1.0727 0.8657 230117_WJC_METTL3_WT_vs_EV_F03.16830.16830.2 3.99 18-Jun K.VIIADC[160.03]GEYV.- "sp|Q9UNP9|PPIE_HUMAN,tr|E9PEQ6|E9PEQ6_HUMAN" 2 1137.5376 - 22341 16830 2 1137.540309 569.7761 Peptidyl-prolyl cis-trans isomerase E OS=Homo sapiens OX=9606 GN=PPIE PE=1 SV=1 3.67 3384.7 - 1.14E+06 - - - 2.3718 - 0.865 0.054 - 60.5 2 2 0 0.0027 10 0 0 0 - - - - - -1.1003 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.16831.16831.2 0.013 18-Sep R.VIAIDIDPVK[136.11].L sp|Q96RS0|TGS1_HUMAN 1 1089.6525 2.48 22342 16831 2 1089.65326 545.8335 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 4.21 3384.8 - 1.09E+06 - - - 0.6874 - 1.779 0.186 - 185.5 1 2 0 0.0007 10 0 0 0 2.30E+07 9.27E+06 - - - 2.0225 0.9901 230117_WJC_METTL3_WT_vs_EV_F03.16832.16832.2 0.0786 18-Aug K.IVAFENAFER[166.11].L sp|O60763|USO1_HUMAN 1 1204.6116 0.84 22343 16832 2 1204.617967 603.3131 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 3384.9 - 829954 - - - 5.2913 - 1.383 0.309 - 125.1 1 2 0 0.0064 10 0 0 0 4.79E+06 5.69E+06 - - - 2.2264 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.16835.16835.2 4.95E-05 18-Oct K.C[160.03]LEPTVALLR[166.11].W "sp|Q8TCG1|CIP2A_HUMAN,tr|A0A087X211|A0A087X211_HUMAN" 2 1180.6514 -1 22346 16835 2 1180.658185 591.333 Protein CIP2A OS=Homo sapiens OX=9606 GN=CIP2A PE=1 SV=2 5.99 3385.3 - 414907 - - - 5.7892 - 1.916 0.441 - 330.6 1 2 0 0.0068 10 0 0 0 0.00E+00 0.00E+00 - - - 4.1111 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16842.16842.2 0.00153 18-Sep R.LLLNNDNLLR.E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1196.6877 1.41 22351 16842 2 1196.691247 599.3511 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3386.1 - 1.51E+06 - - - 2.9465 - 1.938 0.403 - 248 1 2 0 0.0035 10 0 0 0 1.29E+08 9.14E+07 - - - 3.8633 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16846.16846.2 0.0279 18-Sep R.LLLNNDNLLR[166.11].E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1206.696 1.54 22355 16846 2 1206.697041 604.3553 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3386.5 - 839271 - - - 0.8701 - 2.127 0.25 - 247.9 1 2 0 0.001 10 0 0 0 2.54E+08 1.65E+08 - - - 2.9938 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.16847.16847.2 0.00771 14-Sep R.LELSVLYK.E "sp|Q96FW1|OTUB1_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 5 963.5641 2.37 22356 16847 2 963.565684 482.7893 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 6 3386.6 - 568387 - - - 1.6605 - 1.948 0.235 - 214.3 1 2 0 0.0016 8 0 0 0 1.97E+07 8.32E+06 - - - 2.7873 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.16852.16852.2 0.000294 20-Sep R.LYPEGLAQLAR.A "sp|P61421|VA0D1_HUMAN,tr|J3QL14|J3QL14_HUMAN,tr|F5GYQ1|F5GYQ1_HUMAN,tr|R4GN72|R4GN72_HUMAN" 4 1229.6768 1.22 22361 16852 2 1229.681345 615.8457 V-type proton ATPase subunit d 1 OS=Homo sapiens OX=9606 GN=ATP6V0D1 PE=1 SV=1 6 3387.3 - 349636 - - - 3.6782 - 1.61 0.36 - 315.8 1 2 0 0.0045 11 0 0 0 9.77E+06 8.02E+06 - - - 2.9869 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.16855.16855.2 0.00143 16-Sep R.EPGEFALLR[166.11].S sp|O43505|B4GA1_HUMAN 1 1040.553 5.15 22362 16855 2 1040.554193 521.2838 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 4.53 3387.7 - 1.96E+06 - - - 1.1321 - 1.687 0.351 - 401.4 1 2 0 0.0012 9 0 0 0 4.83E+08 9.38E+07 - - - 3.146 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.16856.16856.2 0.136 14-Oct R.DILLQGLK.A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 898.5488 0.9 22363 16856 2 898.549502 450.2817 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3387.8 - 1.18E+06 - - - 0.8169 - 1.849 0.192 - 324 1 2 0 0.0007 8 0 0 0 1.18E+07 1.31E+07 - - - 2.3126 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.16857.16857.2 0.281 22-Aug -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 1.48 22364 16857 2 1306.768603 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3387.9 - 1.07E+06 - - - 0.2472 - 1.412 0.295 - 108.6 1 2 0 0.0003 12 0 0 0 2.36E+07 1.59E+07 - - - 2.1275 0.996 230117_WJC_METTL3_WT_vs_EV_F03.16858.16858.2 0.458 22-Jul -.MVPPVQVSPLIK[136.11].L sp|P56385|ATP5I_HUMAN 1 1314.7825 1.46 22365 16858 2 1314.782827 658.3985 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3388 - 594043 - - - 0.2639 - 1.406 0.191 - 81.7 1 2 0 0.0003 12 0 0 0 2.36E+07 1.62E+07 - - - 1.3482 0.9861 230117_WJC_METTL3_WT_vs_EV_F03.16859.16859.2 0.152 14-Aug R.LELSVLYK[136.11].E "sp|Q96FW1|OTUB1_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 5 971.5783 2.44 22366 16859 2 971.582566 486.7964 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 6 3388.2 - 526019 - - - 4.4073 - 1.591 0.126 - 144.7 1 2 0 0.0043 8 0 0 0 2.03E+07 8.32E+06 - - - 1.3708 0.9853 230117_WJC_METTL3_WT_vs_EV_F03.16862.16862.2 0.712 12-Jun K.VLLPFTR.A sp|Q8TEM1|PO210_HUMAN 1 844.5171 1.77 22367 16862 2 844.517425 423.2658 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 9.72 3388.6 - 1.74E+06 - - - 0.4156 - 1.237 0.084 - 150.1 1 2 0 0.0004 7 0 0 0 4.70E+07 2.65E+07 - - - 0.3352 0.9853 230117_WJC_METTL3_WT_vs_EV_F03.16863.16863.2 6.33 14-Jun K.YVVGLIIK.T "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 903.5793 1.4 22368 16863 2 903.579215 452.7969 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3388.7 - 1.40E+06 - - - -0.1383 - 1.139 0.148 - 101.5 1 2 0 -0.0001 8 0 0 0 4.05E+07 2.90E+07 - - - 0.5266 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.16864.16864.2 0.101 14-Jun K.YVVGLIIK[136.11].T "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 911.5935 1.4 22369 16864 2 911.593888 456.804 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3388.8 - 1.24E+06 - - - 0.3817 - 1.383 0.237 - 102.5 1 2 0 0.0003 8 0 0 0 4.05E+07 2.90E+07 - - - 1.7693 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.16865.16865.2 0.00792 18-Jul K.AVFVPDIYSR.T sp|O94874|UFL1_HUMAN 1 1165.6132 1.45 22370 16865 2 1165.613204 583.8139 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.88 3388.9 - 686288 - - - 0.0386 - 1.633 0.338 - 124.8 1 2 0 0 10 0 0 0 8.76E+06 6.03E+06 - - - 2.9064 1 230117_WJC_METTL3_WT_vs_EV_F03.16867.16867.2 2.55E-05 20-Dec R.FDLALAATEAR.Q sp|Q6PD62|CTR9_HUMAN 1 1176.6139 2.49 22372 16867 2 1176.612319 589.3142 RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1 4.37 3389.2 - 418924 - - - -1.3335 - 2.4 0.532 - 471.8 1 2 0 -0.0016 11 0 0 0 6.52E+06 2.62E+06 - - - 5.3382 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.16872.16872.2 0.00875 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 0.64 22375 16872 2 1006.568665 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3389.8 - 1.29E+06 - - - -1.225 - 1.837 0.469 - 262.3 1 2 0 -0.0012 9 0 0 0 5.81E+07 9.14E+07 - - - 4.264 0.999 230117_WJC_METTL3_WT_vs_EV_F03.16873.16873.2 0.014 16-Jul K.LFSELPLAK.K "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1016.5906 1.26 22376 16873 2 1016.590859 509.3026 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 6 3389.9 - 1.24E+06 - - - 0.2223 - 1.272 0.398 - 124.9 1 2 0 0.0002 9 0 0 0 1.22E+08 9.72E+07 - - - 2.6766 0.983 230117_WJC_METTL3_WT_vs_EV_F03.16874.16874.2 1.02 14-May R.LLEPFEVR[166.11].T sp|Q8WUY1|THEM6_HUMAN 1 1011.5629 32.85 22377 16874 2 1011.564413 506.7887 Protein THEM6 OS=Homo sapiens OX=9606 GN=THEM6 PE=1 SV=2 4.53 3389.9 - 1.04E+06 - - - 1.5432 - 1.112 0.131 - 54.1 3 2 0 0.0016 8 0 0 0 4.80E+09 1.46E+08 - - - 0.1151 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.16875.16875.2 0.00268 22-Nov K.ALLTPVAIAAGR.K sp|P00390|GSHR_HUMAN 1 1151.7026 3.03 22378 16875 2 1151.704279 576.8586 "Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2" 9.79 3390.1 - 200624 - - - 1.4205 - 2.435 0.364 - 334.7 1 2 0 0.0016 12 0 0 0 3.82E+07 1.26E+07 - - - 4.0706 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.16880.16880.2 0.614 12-Jul R.LLQLWEK[136.11].N "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 936.5524 1.31 22381 16880 2 936.554469 469.2835 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 6 3390.8 - 968230 - - - 2.206 - 1.461 0.201 - 123.1 1 2 0 0.0021 7 0 0 0 6.23E+07 4.75E+07 - - - 1.7262 0.994 230117_WJC_METTL3_WT_vs_EV_F03.16881.16881.2 2.58 14-Jun R.LMGDYLLR.G "sp|O60232|ZNRD2_HUMAN,tr|H0YEK1|H0YEK1_HUMAN,tr|E9PK41|E9PK41_HUMAN,tr|H0YEB6|H0YEB6_HUMAN" 4 979.5161 2.13 22382 16881 2 979.519446 490.7653 Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1 5.84 3391 - 396881 - - - 3.4282 - 1.206 0.26 - 65.9 1 2 0 0.0034 8 0 0 0 2.45E+07 1.15E+07 - - - 1.5252 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.16882.16882.2 6.53E-05 24-Sep R.ILGVGPDDPDLVR[166.11].A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1374.7383 2.26 22383 16882 2 1374.742339 688.3764 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3391.1 - 252153 - - - 2.9744 - 2.027 0.356 - 282.7 1 2 0 0.0041 13 0 0 0 5.25E+06 2.32E+06 - - - 3.4825 1 230117_WJC_METTL3_WT_vs_EV_F03.16886.16886.2 9.36E-06 24-Sep R.ILGVGPDDPDLVR.A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1364.73 2.26 22385 16886 2 1364.734648 683.3723 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3391.6 - 280374 - - - 3.4205 - 1.97 0.537 - 258.5 1 2 0 0.0047 13 0 0 0 5.25E+06 2.32E+06 - - - 4.746 0.9957 230117_WJC_METTL3_WT_vs_EV_F03.16894.16894.2 0.00185 16-Sep R.VSLLC[160.03]PLGK.M sp|O75925|PIAS1_HUMAN 1 985.563 1.34 22391 16894 2 985.568206 493.7888 E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=9606 GN=PIAS1 PE=1 SV=2 8.19 3392.7 - 802802 - - - 5.2437 - 1.924 0.302 - 227.8 1 2 0 0.0052 9 0 0 0 1.19E+07 8.94E+06 - - - 3.1632 0.9684 230117_WJC_METTL3_WT_vs_EV_F03.16895.16895.2 0.0615 16-Jul R.LLVAVLTSR.A "sp|Q9P2E5|CHPF2_HUMAN,tr|G5E9W2|G5E9W2_HUMAN,tr|C9JZF7|C9JZF7_HUMAN" 3 970.6175 0.9 22392 16895 2 970.620999 486.316 Chondroitin sulfate glucuronyltransferase OS=Homo sapiens OX=9606 GN=CHPF2 PE=2 SV=2 9.75 3392.8 - 562628 - - - 3.5884 - 1.467 0.044 - 109 2 2 0 0.0035 9 0 0 0 4.44E+06 4.91E+06 - - - 0.3391 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.16899.16899.2 0.00593 18-Aug K.VFEVMLATDR[166.11].S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1189.6041 1.67 22396 16899 2 1189.605828 595.8093 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3393.4 - 133078 - - - 1.482 - 1.661 0.368 - 179.4 1 2 0 0.0018 10 0 0 0 1.91E+07 1.14E+07 - - - 3.1749 0.98 230117_WJC_METTL3_WT_vs_EV_F03.16905.16905.2 0.0265 14-Nov K.MFAEIMMK[136.11].L "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1007.4734 0.94 22400 16905 2 1007.481666 504.744 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 5.75 3394 - 1.14E+06 - - - 8.2374 - 1.984 0.313 - 378.5 1 2 0 0.0083 8 0 0 0 1.41E+07 1.51E+07 - - - 3.4165 1 230117_WJC_METTL3_WT_vs_EV_F03.16910.16910.2 0.000137 18-Sep R.LLYEALVDC[160.03]K[136.11].K "sp|Q7L2H7|EIF3M_HUMAN,tr|J3KNJ2|J3KNJ2_HUMAN,tr|E9PRY0|E9PRY0_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 4 1230.641 0.88 22405 16910 2 1230.636247 616.3278 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 4.37 3394.7 - 167173 - - - -3.8305 - 1.905 0.527 - 257.9 1 2 0 -0.0047 10 0 0 0 4.38E+06 4.99E+06 - - - 4.7309 0.994 230117_WJC_METTL3_WT_vs_EV_F03.16911.16911.2 1.08E-05 18-Aug R.LLYEALVDC[160.03]K.K "sp|Q7L2H7|EIF3M_HUMAN,tr|J3KNJ2|J3KNJ2_HUMAN,tr|E9PRY0|E9PRY0_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 4 1222.6268 0.87 22406 16911 2 1222.635106 612.3207 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 4.37 3394.8 - 143736 - - - 6.8255 - 1.833 0.519 - 175.7 1 2 0 0.0083 10 0 0 0 4.53E+06 5.23E+06 - - - 4.5631 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.16914.16914.2 0.000885 18-Sep R.LGLSTLGELK.Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1029.607 2.63 22407 16914 2 1029.609043 515.8108 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3395.2 - 3.09E+06 - - - 1.9736 - 2.002 0.366 - 173.2 1 2 0 0.002 10 0 0 0 2.51E+08 9.56E+07 - - - 3.6812 0.9214 230117_WJC_METTL3_WT_vs_EV_F03.16917.16917.2 0.0126 22-May R.IINEPTAAAIAY.G "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 16 1245.6605 - 22410 16917 2 1245.662886 623.8375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4 3395.4 - 1.63E+06 - - - 1.9122 - 1.35 0.347 - 80.6 1 1 0 0.0024 12 0 0 0 - - - - - 2.3928 0.9942 230117_WJC_METTL3_WT_vs_EV_F03.16921.16921.2 0.797 12-May K.LLLDMYK.S "sp|O75150|BRE1B_HUMAN,tr|H3BP71|H3BP71_HUMAN" 2 894.4885 0.9 22414 16921 2 894.490053 448.2515 E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5 5.83 3395.7 - 562716 - - - 1.763 - 1.213 0.168 - 67 1 2 0 0.0016 7 0 0 0 7.39E+06 8.22E+06 - - - 0.8932 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.16922.16922.2 0.0106 16-Aug R.ELLTEFGYK[136.11].G sp|P49411|EFTU_HUMAN 1 1106.5739 2.7 22415 16922 2 1106.571456 554.2942 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.53 3395.8 - 443939 - - - -2.233 - 1.763 0.395 - 174.7 1 2 0 -0.0025 9 0 0 0 3.54E+07 1.31E+07 - - - 3.5981 1 230117_WJC_METTL3_WT_vs_EV_F03.16923.16923.2 4.41E-05 18-Oct K.VFEVMLATDR.S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1179.5958 1.67 22416 16923 2 1179.594895 590.8052 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3395.9 - 421427 - - - -0.763 - 2.089 0.525 - 472.8 1 2 0 -0.0009 10 0 0 0 1.92E+07 1.15E+07 - - - 4.9747 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.16927.16927.2 0.018 18-Oct R.LGLSTLGELK[136.11].Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1037.6212 2.63 22418 16927 2 1037.623244 519.8179 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3396.4 - 2.82E+06 - - - 1.9593 - 1.998 0.444 - 164.6 1 2 0 0.002 10 0 0 0 2.51E+08 9.56E+07 - - - 4.2517 0.9825 230117_WJC_METTL3_WT_vs_EV_F03.16931.16931.2 2.11 12-May R.VPFSLLR.G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 830.5014 0.99 22422 16931 2 830.503472 416.258 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3396.7 - 1.57E+06 - - - 2.466 - 1.084 0.164 - 77.2 3 2 0 0.002 7 0 0 0 6.56E+07 6.64E+07 - - - 0.2941 1 230117_WJC_METTL3_WT_vs_EV_F03.16932.16932.2 1.24E-05 18-Nov K.VTDAIVLLDR.E "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1113.6394 3.19 22423 16932 2 1113.642513 557.827 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.21 3396.9 - 660225 - - - 2.8187 - 2.521 0.414 - 312.7 1 2 0 0.0031 10 0 0 0 1.55E+08 4.87E+07 - - - 4.6788 0.9892 230117_WJC_METTL3_WT_vs_EV_F03.16935.16935.2 0.678 16-Jul R.WGEPEPFLR[166.11].L "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 5 1139.5639 2.45 22426 16935 2 1139.567046 570.7892 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.53 3397.3 - 260147 - - - 2.7484 - 1.176 0.167 - 91.4 1 2 0 0.0031 9 0 0 0 4.95E+06 2.02E+06 - - - 0.7425 0.9733 230117_WJC_METTL3_WT_vs_EV_F03.16937.16937.2 0.0468 20-Jun K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.23 22427 16937 2 1235.767436 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3397.5 - 942353 - - - 5.8895 - 1.545 0.196 - 83.8 1 2 0 0.0073 11 0 0 0 1.85E+07 1.50E+07 - - - 1.6632 0.9962 230117_WJC_METTL3_WT_vs_EV_F03.16939.16939.2 0.0525 12-Jul R.VPFSLLR[166.11].G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 840.5097 0.98 22428 16939 2 840.510507 421.2621 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3397.7 - 1.68E+06 - - - 0.9673 - 1.282 0.187 - 222.5 1 2 0 0.0008 7 0 0 0 6.56E+07 6.66E+07 - - - 1.2091 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.16941.16941.2 0.000182 16-Oct R.ELLTEFGYK.G sp|P49411|EFTU_HUMAN 1 1098.5597 2.73 22430 16941 2 1098.563359 550.2871 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.53 3397.9 - 2.29E+06 - - - 3.3061 - 2.146 0.442 - 332 1 2 0 0.0036 9 0 0 0 3.53E+07 1.29E+07 - - - 4.5136 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.16942.16942.2 0.00122 14-Sep K.MFGMVLEK[136.11].L sp|P55060|XPO2_HUMAN 1 961.4856 2.61 22431 16942 2 961.489647 481.7501 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.75 3398.1 - 794891 - - - 4.1613 - 1.589 0.404 - 162 1 2 0 0.004 8 0 0 0 6.15E+07 2.36E+07 - - - 3.4204 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.16949.16949.2 2.07E-05 22-Sep K.VLQGDLVMNVYR.D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1405.7388 2.46 22438 16949 2 1405.741295 703.8767 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3399 - 63266.5 - - - 1.7955 - 1.87 0.449 - 308.5 1 2 0 0.0025 12 0 0 0 2.01E+06 8.18E+05 - - - 4.0035 0.999 230117_WJC_METTL3_WT_vs_EV_F03.16952.16952.2 0.325 14-Jun R.VLFLSTVR.T "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 933.5648 1.93 22439 16952 2 933.566691 467.7897 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 9.72 3399.4 - 2.36E+06 - - - 2.0759 - 1.554 0.292 - 109.6 1 2 0 0.0019 8 0 0 0 4.22E+07 2.19E+07 - - - 2.5266 1 230117_WJC_METTL3_WT_vs_EV_F03.16953.16953.2 0.000155 14-Sep K.VDLVLLGK[136.11].Q sp|P38117|ETFB_HUMAN 1 863.5572 2.62 22440 16953 2 863.558438 432.7859 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3399.4 - 1.65E+06 - - - 1.4869 - 2.076 0.456 - 307.1 1 2 0 0.0013 8 0 0 0 1.72E+08 6.56E+07 - - - 4.6116 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.16954.16954.2 0.015 14-Aug K.AGPIWDLR[166.11].L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 936.5057 0.96 22441 16954 2 936.5079 469.2601 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3399.5 - 2.85E+06 - - - 2.3801 - 1.536 0.36 - 306.3 1 2 0 0.0022 8 0 0 0 4.24E+08 4.44E+08 - - - 2.9937 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.16955.16955.2 0.0101 14-Aug K.AGPIWDLR.L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 926.4974 0.96 22442 16955 2 926.499492 464.256 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3399.6 - 1.99E+06 - - - 2.2569 - 1.419 0.322 - 316.2 1 2 0 0.0021 8 0 0 0 4.24E+08 4.43E+08 - - - 2.4741 0.9914 230117_WJC_METTL3_WT_vs_EV_F03.16956.16956.2 0.0651 14-May K.MFGMVLEK.L sp|P55060|XPO2_HUMAN 1 953.4714 2.66 22443 16956 2 953.474531 477.743 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.75 3399.6 - 1.98E+06 - - - 3.2355 - 1.029 0.272 - 62.1 1 2 0 0.0031 8 0 0 0 6.46E+07 2.43E+07 - - - 1.1352 1 230117_WJC_METTL3_WT_vs_EV_F03.16965.16965.2 3.87E-05 18-Dec K.VTDAIVLLDR[166.11].E "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1123.6476 3.18 22450 16965 2 1123.649944 562.8311 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.21 3400.6 - 2.75E+06 - - - 2.0469 - 2.636 0.442 - 520.1 1 2 0 0.0023 10 0 0 0 1.55E+08 4.87E+07 - - - 5.0104 0.9631 230117_WJC_METTL3_WT_vs_EV_F03.16966.16966.2 0.000771 14-Sep K.PFYPALIR.Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 975.5542 0.77 22451 16966 2 975.556173 488.7844 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.18 3400.7 - 1.16E+06 - - - 2.0347 - 1.552 0.418 - 286.1 1 1 0 0.002 8 0 0 0 5.83E+07 7.61E+07 - - - 3.4534 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.16967.16967.2 0.000779 14-Aug K.VDLVLLGK.Q sp|P38117|ETFB_HUMAN 1 855.543 1.75 22452 16967 2 855.544571 428.7788 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3400.8 - 5.60E+06 - - - 1.89 - 1.848 0.457 - 245.7 1 2 0 0.0016 8 0 0 0 9.27E+07 5.31E+07 - - - 4.268 0.9469 230117_WJC_METTL3_WT_vs_EV_F03.16969.16969.2 0.0134 16-Jul R.LVNHFVEEF.K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1132.5553 - 22454 16969 2 1132.556687 567.2849 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.51 3401 - 1.46E+06 - - - 1.2158 - 1.501 0.347 - 137.7 1 1 0 0.0014 9 0 0 0 - - - - - 2.7785 1 230117_WJC_METTL3_WT_vs_EV_F03.16972.16972.2 4.33E-05 20-Nov R.IDGLAALSMDR[166.11].T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1170.5942 1.78 22457 16972 2 1170.596946 586.3044 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3401.4 - 627208 - - - 2.3219 - 2.277 0.462 - 332.1 1 2 0 0.0027 11 0 0 0 1.35E+07 7.58E+06 - - - 4.6785 0.999 230117_WJC_METTL3_WT_vs_EV_F03.16978.16978.2 0.0146 14-Oct R.LWDLVAGK.T "sp|O43660|PLRG1_HUMAN,tr|H0YA24|H0YA24_HUMAN" 2 900.5069 0.96 22462 16978 2 900.506451 451.2607 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 5.84 3402.1 - 730346 - - - -0.5019 - 1.841 0.319 - 271.6 1 2 0 -0.0005 8 0 0 0 5.58E+07 5.80E+07 - - - 3.2377 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.16980.16980.2 8.38E-06 20-Dec R.IDGLAALSMDR.T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1160.586 1.71 22463 16980 2 1160.587472 581.3003 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3402.4 - 360943 - - - 1.3045 - 2.361 0.405 - 393.6 1 2 0 0.0015 11 0 0 0 1.55E+07 9.04E+06 - - - 4.3559 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.16990.16990.2 0.00918 22-Oct R.AAVLFATDIAAR.G "sp|Q13206|DDX10_HUMAN,tr|A0A3B3ISR7|A0A3B3ISR7_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 3 1217.6768 1.07 22471 16990 2 1217.678823 609.8457 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 5.88 3403.5 - 215236 - - - 1.6433 - 1.935 0.106 - 325.8 1 2 0 0.002 12 0 0 0 4.11E+06 3.84E+06 - - - 1.5601 0.9908 230117_WJC_METTL3_WT_vs_EV_F03.16992.16992.2 0.198 12-Jun R.DGFGFIK.C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 782.3963 1.98 22473 16992 2 782.397684 392.2054 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3403.7 - 1.79E+06 - - - 1.7817 - 0.971 0.219 - 120.9 1 2 0 0.0014 7 0 0 0 7.08E+07 3.57E+07 - - - 0.5648 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.16998.16998.2 0.000616 12-Jul R.YGDFFIR.Q "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|H0Y7E6|H0Y7E6_HUMAN,tr|B0QY90|B0QY90_HUMAN" 4 916.4443 0.62 22477 16998 2 916.446036 459.2294 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 5.84 3404.5 - 2.86E+06 - - - 1.891 - 1.457 0.427 - 130.6 1 2 0 0.0017 7 0 0 0 4.81E+07 7.80E+07 - - - 3.3869 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.16999.16999.2 0.00061 13/22 R.AAVLFATDIAAR[166.11].G "sp|Q13206|DDX10_HUMAN,tr|A0A3B3ISR7|A0A3B3ISR7_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 3 1227.6851 1.07 22478 16999 2 1227.686243 614.8498 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 5.88 3404.6 - 605569 - - - 0.9375 - 2.198 0.351 - 357.6 1 2 0 0.0012 12 0 0 0 4.11E+06 3.84E+06 - - - 3.7053 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.17000.17000.2 0.00192 16-Oct R.FAVGIVIGR.N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 930.5651 1.4 22479 17000 2 930.568406 466.2898 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3404.6 - 9.29E+06 - - - 3.5667 - 1.888 0.392 - 407.8 1 2 0 0.0033 9 0 0 0 2.91E+08 2.07E+08 - - - 3.7739 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.17007.17007.2 0.556 12-Jul R.DGFGFIK[136.11].C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 790.4105 2.07 22484 17007 2 790.412318 396.2125 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3405.5 - 2.63E+06 - - - 2.3127 - 1.245 0.287 - 187.4 1 2 0 0.0018 7 0 0 0 7.06E+07 3.41E+07 - - - 1.8546 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.17012.17012.2 0.189 16-Nov R.FAVGIVIGR[166.11].N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 940.5734 1.4 22487 17012 2 940.575575 471.294 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3406.1 - 3.19E+06 - - - 2.3581 - 1.998 0.393 - 479.7 1 2 0 0.0022 9 0 0 0 2.91E+08 2.07E+08 - - - 3.9454 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.17019.17019.2 0.0103 16-Sep K.LGVSFSFAK[136.11].K sp|Q9UKJ3|GPTC8_HUMAN 1 962.5317 1.61 22492 17019 2 962.53319 482.2731 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 8.75 3406.9 - 363887 - - - 1.5812 - 1.694 0.258 - 140.6 1 2 0 0.0015 9 0 0 0 1.71E+07 1.06E+07 - - - 2.471 0.991 230117_WJC_METTL3_WT_vs_EV_F03.17022.17022.2 2.05 14-Jul R.IAYFTLPK[136.11].T sp|Q92900|RENT1_HUMAN 1 959.5572 1.09 22495 17022 2 959.557024 480.7859 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.59 3407.1 - 732366 - - - -0.1355 - 1.411 0.108 - 91.7 1 2 0 -0.0001 8 0 0 0 3.26E+07 2.98E+07 - - - 0.877 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.17023.17023.2 1.75E-06 18-Oct R.FFNYVPSGIR[166.11].C "sp|Q969X6|UTP4_HUMAN,tr|H3BPD7|H3BPD7_HUMAN" 2 1208.6218 1.32 22496 17023 2 1208.62492 605.3182 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 8.75 3407.2 - 706717 - - - 2.6112 - 1.872 0.503 - 293.4 1 2 0 0.0032 10 0 0 0 1.51E+07 1.14E+07 - - - 4.5053 0.8747 230117_WJC_METTL3_WT_vs_EV_F03.17024.17024.2 1.87 18-May R.IFLPPPPGIR.K "sp|Q8IX18|DHX40_HUMAN,tr|F5H625|F5H625_HUMAN" 2 1105.6648 2.94 22497 17024 2 1105.669552 553.8397 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 9.75 3407.4 - 107544 - - - 4.297 - 1.142 0.067 - 49.1 3 2 0 0.0048 10 0 0 0 4.46E+06 1.52E+06 - - - -0.3081 0.9726 230117_WJC_METTL3_WT_vs_EV_F03.17027.17027.2 0.000203 16-Aug F.VLVLYDEIK.K "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 3 1090.6274 0.23 22498 17027 2 1090.627591 546.321 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 4.37 3407.8 - 1.20E+06 - - - 0.1641 - 1.885 0.488 - 175.7 1 1 0 0.0002 9 0 0 0 1.57E+07 6.96E+07 - - - 4.4793 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.17030.17030.2 0.0522 14-Sep R.ITVLEALR.H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 913.5597 1.2 22501 17030 2 913.562328 457.7871 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3408.1 - 3.03E+06 - - - 2.9128 - 1.951 0.319 - 285.5 1 2 0 0.0027 8 0 0 0 1.02E+08 8.47E+07 - - - 3.412 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.17031.17031.2 0.00304 20-Nov K.ALADVATVLGR.A "sp|Q92542|NICA_HUMAN,tr|H0Y6T7|H0Y6T7_HUMAN" 2 1084.6241 3.67 22502 17031 2 1084.622733 543.3193 Nicastrin OS=Homo sapiens OX=9606 GN=NCSTN PE=1 SV=2 5.88 3408.2 - 1.06E+06 - - - -1.2216 - 2.076 0.205 - 255.8 1 2 0 -0.0013 11 0 0 0 8.37E+06 2.28E+06 - - - 2.5307 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.17036.17036.2 0.269 14-Aug R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 275.32 22505 17036 2 1000.558544 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3408.8 - 4.46E+06 - - - -0.7886 - 1.56 0.23 - 181.4 1 2 0 -0.0008 8 0 0 0 1.28E+08 4.67E+05 - - - 2.0807 0.9832 230117_WJC_METTL3_WT_vs_EV_F03.17045.17045.2 0.319 16-Aug R.GLVGEIIK[136.11]R[166.11].F "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1001.6352 1.77 22512 17045 2 1001.637024 501.8249 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3409.7 - 6.54E+06 - - - 1.7861 - 1.49 0.012 - 181.3 2 2 0 0.0018 9 0 0 0 1.88E+08 1.06E+08 - - - 0.1483 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.17051.17051.2 0.0101 18-Oct R.LLDYVPIGPR.F "sp|P46459|NSF_HUMAN,tr|K7EQD6|K7EQD6_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 4 1141.6495 1.6 22517 17051 2 1141.652811 571.832 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.84 3410.4 - 652975 - - - 2.8608 - 2.003 0.321 - 295.7 1 2 0 0.0033 10 0 0 0 1.38E+07 8.65E+06 - - - 3.3498 0.9668 230117_WJC_METTL3_WT_vs_EV_F03.17052.17052.2 5.66 14-Aug K.LILAGALR[166.11].L "sp|Q13614|MTMR2_HUMAN,tr|A0A6Q8PHS7|A0A6Q8PHS7_HUMAN,tr|C9JEX3|C9JEX3_HUMAN,tr|A0A6Q8PGS5|A0A6Q8PGS5_HUMAN,tr|A0A6Q8PHL9|A0A6Q8PHL9_HUMAN" 5 835.5519 1.42 22518 17052 2 835.551773 418.7832 Myotubularin-related protein 2 OS=Homo sapiens OX=9606 GN=MTMR2 PE=1 SV=4 9.75 3410.6 - 310130 - - - -0.1436 - 1.422 0 - 164.8 2 2 0 -0.0001 8 0 0 0 4.08E+07 2.87E+07 - - - -0.0317 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.17055.17055.2 0.00401 14-Sep R.ITVLEALR[166.11].H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 923.5679 1.2 22519 17055 2 923.570035 462.7912 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3411 - 6.07E+06 - - - 2.2716 - 1.838 0.387 - 309.5 1 2 0 0.0021 8 0 0 0 1.02E+08 8.48E+07 - - - 3.7345 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.17056.17056.2 0.00501 14-Aug K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 0.97 22520 17056 2 988.572242 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3411 - 3.09E+06 - - - 1.6954 - 1.666 0.377 - 294.9 1 2 0 0.0017 8 0 0 0 2.82E+08 2.89E+08 - - - 3.3644 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.17057.17057.2 0.0688 14-Sep K.AGISFIIK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 847.5167 0.92 22521 17057 2 847.517422 424.7656 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.8 3411.1 - 1.59E+06 - - - 0.8047 - 1.561 0.157 - 187.3 1 2 0 0.0007 8 0 0 0 1.66E+09 1.81E+09 - - - 1.5435 0.9957 230117_WJC_METTL3_WT_vs_EV_F03.17059.17059.2 2.7 14-Aug R.EILETLIK[136.11].G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 965.5888 1.64 22523 17059 2 965.589608 483.8017 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3411.3 - 374978 - - - 0.786 - 1.457 0.13 - 158.4 1 2 0 0.0008 8 0 0 0 1.11E+08 6.78E+07 - - - 1.1361 0.958 230117_WJC_METTL3_WT_vs_EV_F03.17064.17064.2 0.00829 16-Oct R.LLDLELTSR.F "sp|Q9Y2Q9|RT28_HUMAN,tr|H0YAT2|H0YAT2_HUMAN,tr|E5RK86|E5RK86_HUMAN,tr|E5RGC7|E5RGC7_HUMAN,tr|E5RFH3|E5RFH3_HUMAN" 5 1058.5972 1.2 22526 17064 2 1058.607326 530.3059 "28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1" 4.37 3412 - 586232 - - - 9.5891 - 2.055 0.212 - 241.4 1 2 0 0.0102 9 0 0 0 1.99E+07 1.67E+07 - - - 2.6874 0.9956 230117_WJC_METTL3_WT_vs_EV_F03.17065.17065.2 0.121 12-Jul K.LYIEFVK[136.11].G "sp|Q14165|MLEC_HUMAN,tr|H0YG07|H0YG07_HUMAN,tr|F5H1S8|F5H1S8_HUMAN" 3 918.5306 1.43 22527 17065 2 918.533742 460.2726 Malectin OS=Homo sapiens OX=9606 GN=MLEC PE=1 SV=1 6 3412.1 - 549623 - - - 3.4152 - 1.471 0.207 - 132.3 1 2 0 0.0031 7 0 0 0 9.47E+06 6.64E+06 - - - 1.7918 0.9496 230117_WJC_METTL3_WT_vs_EV_F03.17066.17066.2 0.00359 14-Sep C.LNLWGYER.V sp|Q86U44|MTA70_HUMAN 1 1049.5294 0.11 22528 17066 2 1049.53227 525.772 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3412.2 - 471377 - - - 2.706 - 2.225 0.269 - 258.1 1 1 0 0.0028 8 0 0 0 1.20E+07 1.11E+08 - - - 3.439 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.17072.17072.2 0.237 14-Oct K.LMNLWTER[166.11].F "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1071.5411 0.37 22532 17072 2 1071.544184 536.7778 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 3413 - 2.04E+06 - - - 2.9052 - 1.917 0.311 - 471.3 1 2 0 0.0031 8 0 0 0 2.23E+08 6.07E+08 - - - 3.2997 0.984 230117_WJC_METTL3_WT_vs_EV_F03.17073.17073.2 1.32 14-Jul R.EILETLIK.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 957.5746 1.64 22533 17073 2 957.577914 479.7946 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3413.1 - 2.84E+06 - - - 3.4097 - 1.348 0.109 - 164.5 1 2 0 0.0033 8 0 0 0 1.11E+08 6.78E+07 - - - 0.7457 0.9275 230117_WJC_METTL3_WT_vs_EV_F03.17074.17074.2 0.000229 16-Nov F.ADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 952.5957 6.42 22534 17074 2 952.599484 477.3051 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3413.2 - 1.08E+06 - - - 3.9534 - 1.819 0.466 - 325.3 1 1 0 0.0038 9 0 0 0 3.17E+07 4.94E+06 - - - 4.2126 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.17082.17082.2 0.0742 12-Jul K.VFYIGLR.G "sp|Q9GZP4|PITH1_HUMAN,tr|X6R8S9|X6R8S9_HUMAN" 2 866.5014 7.05 22540 17082 2 866.503135 434.258 PITH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PITHD1 PE=1 SV=1 8.72 3414.2 - 733312 - - - 1.9746 - 1.468 0.168 - 195.7 1 2 0 0.0017 7 0 0 0 1.35E+07 1.92E+06 - - - 1.4977 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.17084.17084.2 6.43E-05 14-Oct K.LMNLWTER.F "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1061.5328 0.37 22542 17084 2 1061.537152 531.7737 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 3414.4 - 1.81E+06 - - - 4.0988 - 1.897 0.406 - 409 1 2 0 0.0044 8 0 0 0 2.23E+08 6.07E+08 - - - 3.9694 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.17085.17085.2 0.0847 16-Oct K.SSLNPILFR.G "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1045.592 1.46 22543 17085 2 1045.596045 523.8033 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 9.47 3414.5 - 1.52E+06 - - - 3.8399 - 1.927 0.295 - 330.2 1 2 0 0.004 9 0 0 0 1.01E+08 6.92E+07 - - - 3.1163 0.9827 230117_WJC_METTL3_WT_vs_EV_F03.17086.17086.2 0.509 14-Jun K.FIIPNVVK[136.11].Y "sp|P00338|LDHA_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 3 936.5888 0.91 22544 17086 2 936.591759 469.3017 L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2 8.75 3414.6 - 1.44E+06 - - - 3.1711 - 1.276 0.138 - 94 3 2 0 0.003 8 0 0 0 4.26E+07 4.70E+07 - - - 0.5813 0.998 230117_WJC_METTL3_WT_vs_EV_F03.17087.17087.2 0.00213 16-Aug K.SSLNPILFR[166.11].G "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1055.6003 1.45 22545 17087 2 1055.603935 528.8074 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 9.47 3414.7 - 1.37E+06 - - - 3.4435 - 1.636 0.286 - 162.2 1 2 0 0.0036 9 0 0 0 9.88E+07 6.80E+07 - - - 2.5764 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.17088.17088.2 0.204 16-Aug R.VLIFSQMTR.V "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 1093.5954 0.9 22546 17088 2 1093.598441 547.805 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 9.72 3414.8 - 818943 - - - 2.7798 - 1.817 0.271 - 183.4 1 2 0 0.003 9 0 0 0 1.60E+07 1.77E+07 - - - 2.7693 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.17089.17089.2 0.0176 12-Jun K.ISFELMR.E "sp|Q9UNE7|CHIP_HUMAN,tr|H3BUD0|H3BUD0_HUMAN,tr|H3BTA3|H3BTA3_HUMAN" 3 894.4633 3.18 22547 17089 2 894.466475 448.2389 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 6 3415 - 529575 - - - 3.5228 - 1.478 0.308 - 89 1 2 0 0.0032 7 0 0 0 2.47E+07 7.76E+06 - - - 2.5528 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.17090.17090.2 0.00286 18-Oct R.LGGIGQFLAK[136.11].A sp|Q08211|DHX9_HUMAN 1 1010.6004 0.85 22548 17090 2 1010.604268 506.3075 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3415.1 - 427232 - - - 3.8116 - 2.096 0.311 - 205.6 1 2 0 0.0039 10 0 0 0 3.51E+08 4.15E+08 - - - 3.4025 0.8531 230117_WJC_METTL3_WT_vs_EV_F03.17091.17091.2 5 12-May R.GEILIFK.D sp|P08254|MMP3_HUMAN 1 818.4902 1.03 22549 17091 2 818.492084 410.2524 Stromelysin-1 OS=Homo sapiens OX=9606 GN=MMP3 PE=1 SV=2 6 3415.2 - 268766 - - - 2.3128 - 0.995 0.001 - 80.3 3 2 0 0.0019 7 0 0 0 1.08E+08 1.04E+08 - - - -1.1812 0.9447 230117_WJC_METTL3_WT_vs_EV_F03.17093.17093.2 0.477 22-Jul K.LIETFSPTESLR.M sp|A6NGG8|PCARE_HUMAN 1 1391.7296 2.15 22551 17093 2 1391.726034 696.8721 Photoreceptor cilium actin regulator OS=Homo sapiens OX=9606 GN=PCARE PE=1 SV=1 4.53 3415.5 - 134721 - - - -2.5953 - 1.442 0.088 - 50.1 1 2 0 -0.0036 12 0 0 0 1.24E+07 5.77E+06 - - - 0.6529 0.997 230117_WJC_METTL3_WT_vs_EV_F03.17098.17098.2 0.00822 14-Jul K.AVPSWFVR[166.11].V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 970.5264 2.48 22555 17098 2 970.528264 486.2705 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3416.2 - 1.87E+06 - - - 1.9134 - 1.41 0.184 - 210.3 1 2 0 0.0019 8 0 0 0 1.39E+08 5.58E+07 - - - 1.4357 0.9655 230117_WJC_METTL3_WT_vs_EV_F03.17100.17100.2 0.0131 14-Sep R.IASFLQLK.N "sp|P42694|HELZ_HUMAN,tr|J3KT20|J3KT20_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 4 918.5539 0.63 22557 17100 2 918.562033 460.2842 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.75 3416.4 - 537240 - - - 8.9042 - 1.777 0.284 - 155.9 1 2 0 0.0082 8 0 0 0 3.09E+07 4.87E+07 - - - 2.87 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.17102.17102.2 0.0203 16-Sep K.LNNLVLFDK[136.11].A sp|P62851|RS25_HUMAN 1 1082.6215 1.04 22559 17102 2 1082.620782 542.318 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3416.6 - 242922 - - - -0.7057 - 2.298 0.345 - 262.3 1 2 0 -0.0008 9 0 0 0 1.01E+09 9.74E+08 - - - 3.9961 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.17106.17106.2 0.00161 14-Jun K.AVPSWFVR.V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 960.5181 1.85 22561 17106 2 960.519853 481.2663 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3417.1 - 4.89E+06 - - - 1.7865 - 1.383 0.369 - 122.3 1 2 0 0.0017 8 0 0 0 9.89E+07 5.35E+07 - - - 2.7438 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.17107.17107.2 3.15 14-Aug R.LLLAALGR.R "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 825.5436 1.39 22562 17107 2 825.544758 413.7791 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 9.75 3417.2 - 3.77E+06 - - - 1.3749 - 1.578 0.132 - 170.6 1 2 0 0.0011 8 0 0 0 3.97E+07 2.86E+07 - - - 1.3913 0.913 230117_WJC_METTL3_WT_vs_EV_F03.17108.17108.2 3.85 14-Jun K.FIIPNVVK.Y "sp|P00338|LDHA_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 3 928.5746 0.9 22563 17108 2 928.575954 465.2946 L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2 8.75 3417.2 - 2.74E+06 - - - 1.47 - 0.907 0.04 - 96.4 1 2 0 0.0014 8 0 0 0 4.32E+07 4.77E+07 - - - -0.9584 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.17109.17109.2 12.5 16-Oct K.RVLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1037.7073 1.31 22564 17109 2 1037.709107 519.8609 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3417.3 - 2.56E+06 - - - 1.7086 - 2.018 0.28 - 164.8 1 2 0 0.0018 9 0 0 0 2.06E+08 1.57E+08 - - - 3.1398 0.999 230117_WJC_METTL3_WT_vs_EV_F03.17110.17110.2 0.00157 16-Jul R.AGFVPVYLR[166.11].Q "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1030.5839 0.73 22565 17110 2 1030.58658 516.2992 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 8.79 3417.4 - 2.48E+06 - - - 2.5791 - 1.48 0.348 - 156.8 1 2 0 0.0027 9 0 0 0 5.13E+07 7.06E+07 - - - 2.7447 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.17116.17116.2 0.273 22-Oct -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 1.14 22570 17116 2 1306.768622 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3418 - 261966 - - - 0.2617 - 1.628 0.179 - 197.1 1 2 0 0.0003 12 0 0 0 9.83E+06 8.64E+06 - - - 1.6453 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.17119.17119.2 0.0655 14-Aug R.IAYFTLPK.T sp|Q92900|RENT1_HUMAN 1 951.543 0.56 22572 17119 2 951.546933 476.7788 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.59 3418.3 - 1.96E+06 - - - 4.1816 - 1.668 0.311 - 183.4 1 2 0 0.004 8 0 0 0 3.00E+07 5.31E+07 - - - 2.8798 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.17120.17120.2 0.00207 18-Nov R.LGGIGQFLAK.A sp|Q08211|DHX9_HUMAN 1 1002.5862 0.81 22573 17120 2 1002.58873 502.3004 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3418.4 - 6.16E+06 - - - 2.5075 - 2.243 0.295 - 284.4 1 2 0 0.0025 10 0 0 0 3.52E+08 4.33E+08 - - - 3.4739 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.17122.17122.2 0.00117 18-Oct K.VALDLDPYVK.K sp|O95295|SNAPN_HUMAN 1 1131.6176 2.39 22575 17122 2 1131.618063 566.8161 SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN PE=1 SV=1 4.21 3418.6 - 1.27E+06 - - - 0.4304 - 2.047 0.393 - 320.4 1 2 0 0.0005 10 0 0 0 2.48E+07 1.04E+07 - - - 3.9432 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.17127.17127.2 0.00289 26-Oct R.LGGIPVGVVAVETR.T "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 1365.798 2.59 22580 17127 2 1365.798193 683.9063 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 6 3419.3 - 243640 - - - 0.1413 - 1.762 0.382 - 261.5 1 2 0 0.0002 14 0 0 0 2.22E+06 8.56E+05 - - - 3.2839 0.9447 230117_WJC_METTL3_WT_vs_EV_F03.17131.17131.2 3.77 12-May K.EGIILFK[136.11].E sp|P05455|LA_HUMAN 1 826.5044 1.03 22582 17131 2 826.505059 414.2595 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 6.1 3419.8 - 4.40E+06 - - - 0.8082 - 1.074 0.015 - 80.8 1 2 0 0.0007 7 0 0 0 1.07E+08 1.04E+08 - - - -0.6222 0.9864 230117_WJC_METTL3_WT_vs_EV_F03.17132.17132.2 0.163 16-Jul R.AGFVPVYLR.Q "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1020.5757 0.73 22583 17132 2 1020.577183 511.2951 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 8.79 3419.9 - 3.01E+06 - - - 1.5001 - 1.33 0.054 - 139.6 1 2 0 0.0015 9 0 0 0 5.13E+07 7.08E+07 - - - 0.2644 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.17134.17134.2 0.151 14-Jun R.VIPLPQWK.A sp|Q96ES7|SGF29_HUMAN 1 979.5855 1.99 22585 17134 2 979.586479 490.8 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 8.72 3420 - 1.18E+06 - - - 1.0117 - 1.261 0.305 - 116.8 1 2 0 0.001 8 0 0 0 1.94E+07 9.77E+06 - - - 1.9928 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17138.17138.2 0.00115 18-Aug R.VLISTDVWAR[166.11].G "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1168.648 0.93 22587 17138 2 1168.648652 585.3313 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.81 3420.6 - 7.11E+06 - - - 0.5767 - 1.916 0.445 - 162.8 1 2 0 0.0007 10 0 0 0 1.95E+08 2.10E+08 - - - 4.1426 0.9812 230117_WJC_METTL3_WT_vs_EV_F03.17144.17144.2 1.11 12-Aug K.LPLISLR.L "sp|Q96RL7|VP13A_HUMAN,sp|Q6UXB3|LYPD2_HUMAN,sp|Q6DN12|MCTP2_HUMAN,tr|I6L8E2|I6L8E2_HUMAN" 4 810.5327 1.44 22591 17144 2 810.533055 406.2736 Vacuolar protein sorting-associated protein 13A OS=Homo sapiens OX=9606 GN=VPS13A PE=1 SV=2 9.75 3421.4 - 1.22E+06 - - - 0.4084 - 1.302 0.04 - 207.5 1 2 0 0.0003 7 0 0 0 1.34E+07 9.29E+06 - - - 0.1725 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17145.17145.2 0.0114 16-Nov K.LNNLVLFDK.A sp|P62851|RS25_HUMAN 1 1074.6073 1.04 22592 17145 2 1074.608383 538.3109 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3421.4 - 4.71E+07 - - - 0.965 - 2.418 0.353 - 408.3 1 2 0 0.001 9 0 0 0 1.01E+09 9.74E+08 - - - 4.2023 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.17146.17146.2 0.0489 15/16 K.R[166.11]VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1057.7239 1.31 22593 17146 2 1057.726031 529.8692 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3421.4 - 1.22E+07 - - - 2.0393 - 2.413 0.282 - 439.2 1 2 0 0.0022 9 0 0 0 2.06E+08 1.57E+08 - - - 3.6716 0.9931 230117_WJC_METTL3_WT_vs_EV_F03.17147.17147.3 8.77E-08 19/48 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.73 22594 17147 3 1574.908849 525.975 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3421.6 - 1.03E+06 - - - 3.5907 - 3.002 0.488 - 561.8 1 2 1 0.0057 13 0 0 0 7.71E+06 4.46E+06 - - - 6.9596 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.17153.17153.2 0.00214 14-Sep R.TFLVPEIK.S sp|Q9P1Y5|CAMP3_HUMAN 1 945.5535 0.82 22598 17153 2 945.55479 473.784 Calmodulin-regulated spectrin-associated protein 3 OS=Homo sapiens OX=9606 GN=CAMSAP3 PE=1 SV=2 5.66 3422.4 - 352495 - - - 1.3442 - 1.785 0.352 - 266.4 1 2 0 0.0013 8 0 0 0 1.27E+07 1.55E+07 - - - 3.388 0.9932 230117_WJC_METTL3_WT_vs_EV_F03.17161.17161.2 0.248 14-May K.LFIGMISK.K "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 907.5201 1.76 22604 17161 2 907.520779 454.7673 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.75 3423.4 - 1.12E+06 - - - 0.7361 - 1.08 0.207 - 59.8 1 2 0 0.0007 8 0 0 0 1.14E+07 6.48E+06 - - - 0.8018 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.17163.17163.2 0.0247 20-Oct K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 2.26 22606 17163 2 1245.772175 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3423.5 - 687489 - - - 3.0078 - 2.008 0.359 - 253.1 1 2 0 0.0037 11 0 0 0 2.77E+07 1.23E+07 - - - 3.5773 0.9898 230117_WJC_METTL3_WT_vs_EV_F03.17167.17167.2 2.06 12-Jun K.GLLDDLR.N sp|Q07065|CKAP4_HUMAN 1 800.4392 1.35 22608 17167 2 800.4419 401.2269 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.21 3424 - 1.58E+06 - - - 3.3507 - 1.144 0.215 - 140 1 2 0 0.0027 7 0 0 0 3.35E+07 2.48E+07 - - - 1.0544 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.17168.17168.2 0.000571 14-Sep K.MVGFIIGR.G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 891.5 1.48 22609 17168 2 891.500546 446.7573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3424 - 2.06E+06 - - - 0.5631 - 1.529 0.442 - 318.6 1 2 0 0.0005 8 0 0 0 5.46E+08 3.69E+08 - - - 3.5861 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.17173.17173.2 0.00806 14-Jun K.LFDFVNAK.K "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 952.5018 0.5 22612 17173 2 952.503057 477.2582 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 5.84 3424.6 - 643344 - - - 1.3008 - 1.202 0.369 - 79.8 1 2 0 0.0012 8 0 0 0 5.57E+07 1.11E+08 - - - 2.3209 0.9689 230117_WJC_METTL3_WT_vs_EV_F03.17175.17175.2 8.22E-05 22-Sep R.VINEPTAAALAY.G "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1231.6449 - 22613 17175 2 1231.646718 616.8297 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4 3424.9 - 1.73E+06 - - - 1.5142 - 1.646 0.434 - 179.2 1 1 0 0.0019 12 0 0 0 - - - - - 3.5572 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.17179.17179.2 0.00121 22-Aug R.IVPGQFLAVDPK.G sp|Q15393|SF3B3_HUMAN 1 1282.7285 1.28 22616 17179 2 1282.730729 642.3715 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3425.3 - 455399 - - - 1.719 - 1.669 0.341 - 141.9 1 2 0 0.0022 12 0 0 0 3.01E+07 2.35E+07 - - - 2.9067 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.17181.17181.2 0.000772 22-Sep R.ILYIVASDPYSR.L "sp|Q9ULT8|HECD1_HUMAN,tr|H0YJD4|H0YJD4_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN,tr|H0YJP0|H0YJP0_HUMAN" 4 1395.7398 5.09 22618 17181 2 1395.747117 698.8772 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 5.83 3425.5 - 278080 - - - 5.2302 - 1.905 0.417 - 289.9 1 2 0 0.0073 12 0 0 0 4.25E+06 8.36E+05 - - - 3.8144 0.9952 230117_WJC_METTL3_WT_vs_EV_F03.17184.17184.2 0.0173 24-Aug K.LLPHQLYGVVPQA.- "sp|P18887|XRCC1_HUMAN,tr|F5H8D7|F5H8D7_HUMAN" 2 1433.8031 - 22621 17184 2 1433.800391 717.9088 DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2 6.74 3425.9 - 92449.8 - - - -1.8789 - 1.648 0.279 - 150.6 1 2 0 -0.0027 13 0 0 0 - - - - - 2.383 0.9952 230117_WJC_METTL3_WT_vs_EV_F03.17188.17188.2 0.0204 16-Aug R.FGIWTGEYK[136.11].C sp|Q9NUD5|ZCHC3_HUMAN 1 1107.548 1.84 22623 17188 2 1107.551499 554.7813 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 6 3426.5 - 1.30E+06 - - - 3.1177 - 1.509 0.178 - 118.9 1 2 0 0.0035 9 0 0 0 1.85E+07 1.00E+07 - - - 1.545 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17189.17189.2 4.06E-05 22-Aug R.IVPGQFLAVDPK[136.11].G sp|Q15393|SF3B3_HUMAN 1 1290.7427 1.28 22624 17189 2 1290.744956 646.3786 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3426.6 - 582206 - - - 1.7292 - 1.752 0.477 - 102.5 1 2 0 0.0022 12 0 0 0 3.01E+07 2.35E+07 - - - 4.0389 0.9956 230117_WJC_METTL3_WT_vs_EV_F03.17191.17191.2 0.0472 20-Sep R.LYPVLQQSLVR[166.11].A sp|Q5RKV6|EXOS6_HUMAN 1 1324.7742 0.96 22626 17191 2 1324.778595 663.3944 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.75 3426.8 - 905657 - - - 3.2858 - 1.371 0.245 - 135.7 1 2 0 0.0044 11 0 0 0 9.46E+06 9.87E+06 - - - 1.7028 0.9912 230117_WJC_METTL3_WT_vs_EV_F03.17198.17198.2 0.426 18-Jun K.VIPYIASQFR.K sp|Q9NU22|MDN1_HUMAN 1 1192.6604 0.22 22633 17198 2 1192.664703 597.3375 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 8.72 3427.7 - 131481 - - - 3.571 - 1.28 0.21 - 81.6 1 2 0 0.0043 10 0 0 0 1.56E+06 6.96E+06 - - - 1.2798 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.17201.17201.2 0.0493 18-Oct R.LINLVGESLR.L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1112.6554 5.16 22635 17201 2 1112.657505 557.335 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6 3428.1 - 252107 - - - 1.9287 - 2.325 0.251 - 225.2 1 2 0 0.0021 10 0 0 0 6.52E+07 1.26E+07 - - - 3.2493 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.17202.17202.2 0.0132 20-Jul K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.12 22636 17202 2 1235.763855 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3428.2 - 286675 - - - 2.9917 - 1.737 0.36 - 143 1 2 0 0.0037 11 0 0 0 1.22E+07 1.09E+07 - - - 3.1925 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.17203.17203.2 0.638 14-Aug K.GWGLLGPR.N "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 854.4763 0.85 22637 17203 2 854.478502 428.2454 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 9.75 3428.3 - 1.69E+06 - - - 2.6098 - 1.49 0.181 - 221.8 1 2 0 0.0022 8 0 0 0 1.95E+07 2.28E+07 - - - 1.5799 0.9948 230117_WJC_METTL3_WT_vs_EV_F03.17206.17206.2 0.444 12-Jul R.GFLYFNR[166.11].Q sp|Q10570|CPSF1_HUMAN 1 925.4686 1.68 22640 17206 2 925.470673 463.7416 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3428.6 - 786573 - - - 2.2864 - 1.412 0.133 - 191.9 1 2 0 0.0021 7 0 0 0 1.21E+07 7.15E+06 - - - 1.1158 0.9666 230117_WJC_METTL3_WT_vs_EV_F03.17210.17210.2 0.0837 14-Jul R.MYLSLIAK.S sp|Q99959|PKP2_HUMAN 1 937.5307 0.61 22644 17210 2 937.532834 469.7726 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 8.34 3429 - 244263 - - - 2.3029 - 1.147 0.048 - 109.3 1 2 0 0.0022 8 0 0 0 4.72E+06 7.77E+06 - - - -0.1915 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.17214.17214.2 0.0975 14-Oct R.IVEVLLMK[136.11].D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 951.5918 0.96 22646 17214 2 951.593768 476.8032 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3429.6 - 1.17E+07 - - - 2.0418 - 2.083 0.237 - 261.3 1 2 0 0.0019 8 0 0 0 3.39E+08 3.53E+08 - - - 3.004 0.9125 230117_WJC_METTL3_WT_vs_EV_F03.17220.17220.2 3.35 16-Jun R.MLPPPPMWR.R "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 5 1123.5671 0.77 22652 17220 2 1123.570884 562.7908 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 9.5 3430.2 - 306723 - - - 3.3874 - 1.072 0.043 - 75.7 1 2 0 0.0038 9 0 0 0 1.17E+07 1.52E+07 - - - -0.4415 1 230117_WJC_METTL3_WT_vs_EV_F03.17222.17222.2 0.000205 24-Dec K.LLLGAGAVAYGVR[166.11].E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1268.748 1.33 22654 17222 2 1268.750571 635.3813 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3430.5 - 220857 - - - 2.0051 - 2.372 0.481 - 504.7 1 2 0 0.0025 13 0 0 0 1.32E+08 9.87E+07 - - - 4.8097 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.17227.17227.2 2.41E-05 14-Sep R.IVEVLLMK.D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 943.5776 0.96 22657 17227 2 943.579871 472.7961 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3431.2 - 1.83E+07 - - - 2.3803 - 2.082 0.228 - 234.4 1 2 0 0.0022 8 0 0 0 3.40E+08 3.53E+08 - - - 2.936 1 230117_WJC_METTL3_WT_vs_EV_F03.17228.17228.2 0.00866 18-Nov K.VVDLLAPYAK.G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1087.6277 1.57 22658 17228 2 1087.630563 544.8211 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3431.2 - 7.29E+06 - - - 2.5891 - 2.325 0.484 - 398.5 1 2 0 0.0028 10 0 0 0 4.86E+08 3.09E+08 - - - 4.97 1 230117_WJC_METTL3_WT_vs_EV_F03.17229.17229.2 0.00304 18-Nov K.VVDLLAPYAK[136.11].G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1095.6419 1.57 22659 17229 2 1095.645164 548.8282 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3431.3 - 5.58E+06 - - - 2.9362 - 2.154 0.484 - 447.2 1 2 0 0.0032 10 0 0 0 4.90E+08 3.12E+08 - - - 4.7567 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17230.17230.2 0.000812 24-Nov K.LLLGAGAVAYGVR.E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1258.7398 1.33 22660 17230 2 1258.742781 630.3772 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3431.4 - 1.10E+06 - - - 2.4024 - 2.173 0.463 - 367.9 1 2 0 0.003 13 0 0 0 1.32E+08 9.87E+07 - - - 4.4517 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17236.17236.2 0.000219 16-Aug R.TFTNVYWMK[136.11].V sp|Q9HBH1|DEFM_HUMAN 1 1196.578 1.07 22666 17236 2 1196.580212 599.2963 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 8.26 3432.1 - 251555 - - - 1.877 - 1.619 0.526 - 190.7 1 2 0 0.0022 9 0 0 0 8.07E+06 7.51E+06 - - - 4.3192 1 230117_WJC_METTL3_WT_vs_EV_F03.17238.17238.2 0.000235 14-Oct K.MVGFIIGR[166.11].G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 901.5083 1.49 22667 17238 2 901.510356 451.7614 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3432.3 - 2.43E+07 - - - 2.2651 - 1.91 0.565 - 377 1 2 0 0.002 8 0 0 0 5.48E+08 3.69E+08 - - - 5.1651 0.9282 230117_WJC_METTL3_WT_vs_EV_F03.17241.17241.2 0.0076 14-Aug V.VGDIAQVK[136.11].Y "sp|Q01814|AT2B2_HUMAN,sp|P20020|AT2B1_HUMAN,sp|Q16720|AT2B3_HUMAN,sp|P23634|AT2B4_HUMAN,tr|A0A804HKZ0|A0A804HKZ0_HUMAN,tr|A0A2U3TZI3|A0A2U3TZI3_HUMAN,tr|A0A2U3U055|A0A2U3U055_HUMAN" 7 836.4847 1.62 22669 17241 2 836.486784 419.2496 Plasma membrane calcium-transporting ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2B2 PE=1 SV=2 5.81 3432.6 - 556052 - - - 2.4699 - 1.528 0.33 - 148.5 1 1 0 0.0021 8 0 0 0 1.69E+07 1.04E+07 - - - 2.7564 0.9721 230117_WJC_METTL3_WT_vs_EV_F03.17242.17242.2 0.267 14-Jul R.LLNIWQER.S sp|Q9NQG5|RPR1B_HUMAN 1 1070.5873 2.69 22670 17242 2 1070.592289 536.3009 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 6 3432.7 - 1.13E+06 - - - 4.6797 - 1.57 0.076 - 144.5 1 2 0 0.005 8 0 0 0 6.77E+07 2.52E+07 - - - 0.9612 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.17248.17248.2 0.0323 16-Jun R.AFLGQVLVR.R "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1001.6022 0.27 22674 17248 2 1001.604143 501.8084 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 9.79 3433.4 - 4.49E+06 - - - 1.9389 - 1.401 0.387 - 97.7 1 2 0 0.0019 9 0 0 0 7.88E+07 2.96E+08 - - - 2.8743 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.17251.17251.2 0.0579 14-Aug R.LLNIWQER[166.11].S sp|Q9NQG5|RPR1B_HUMAN 1 1080.5955 3.07 22677 17251 2 1080.597216 541.3051 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 6 3433.6 - 999456 - - - 1.5427 - 1.921 0.214 - 174.5 1 2 0 0.0017 8 0 0 0 6.70E+07 2.18E+07 - - - 2.59 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.17252.17252.2 0.0117 16-Jul R.TPLDLAAFK.G "sp|O15084|ANR28_HUMAN,tr|B4DIW9|B4DIW9_HUMAN" 2 974.5437 1.91 22678 17252 2 974.545397 488.2791 Serine\threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5 5.5 3433.6 - 940332 - - - 1.7588 - 1.443 0.278 - 148.7 1 2 0 0.0017 9 0 0 0 2.18E+07 1.14E+07 - - - 2.1547 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.17253.17253.2 0.0382 16-Sep R.TPLDLAAFK[136.11].G "sp|O15084|ANR28_HUMAN,tr|B4DIW9|B4DIW9_HUMAN" 2 982.5579 1.96 22679 17253 2 982.559401 492.2862 Serine\threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5 5.5 3433.7 - 823856 - - - 1.5449 - 1.552 0.341 - 217.7 1 2 0 0.0015 9 0 0 0 2.12E+07 1.08E+07 - - - 2.8308 0.985 230117_WJC_METTL3_WT_vs_EV_F03.17254.17254.2 1.68 12-Jun R.VLFSLVK.R "sp|Q14999|CUL7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 2 804.5109 0.95 22680 17254 2 804.512365 403.2627 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 8.72 3433.8 - 757868 - - - 1.7887 - 1.21 0.079 - 108.3 1 2 0 0.0014 7 0 0 0 7.28E+06 7.68E+06 - - - 0.228 0.9932 230117_WJC_METTL3_WT_vs_EV_F03.17256.17256.2 0.328 14-Jun K.AITAATLK.F sp|P11277|SPTB1_HUMAN 1 787.4804 0.57 22682 17256 2 787.482112 394.7475 "Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB PE=1 SV=5" 8.8 3434 - 475603 - - - 2.2324 - 1.296 0.145 - 104.6 1 2 0 0.0018 8 0 0 0 7.03E+06 1.23E+07 - - - 0.8934 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.17262.17262.2 0.0313 12-Jun R.DFYFSVK.L sp|Q9NY12|GAR1_HUMAN 1 904.4331 0.65 22686 17262 2 904.43428 453.2238 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3434.8 - 5.54E+06 - - - 1.3379 - 1.071 0.337 - 150.9 1 2 0 0.0012 7 0 0 0 7.64E+07 1.18E+08 - - - 1.747 1 230117_WJC_METTL3_WT_vs_EV_F03.17266.17266.2 0.0014 18-Dec K.VVDDEIYYFR.K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1317.6241 1.95 22690 17266 2 1317.626435 659.8193 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3435.2 - 1.15E+06 - - - 1.7585 - 2.23 0.453 - 532.6 1 2 0 0.0023 10 0 0 0 2.41E+07 1.24E+07 - - - 4.6248 0.921 230117_WJC_METTL3_WT_vs_EV_F03.17267.17267.2 2.06 16-May R.MLPPPPMWR[166.11].R "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 5 1133.5753 0.79 22691 17267 2 1133.57972 567.795 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 9.5 3435.3 - 876889 - - - 3.8568 - 0.922 0.138 - 56.8 1 2 0 0.0044 9 0 0 0 2.29E+07 2.90E+07 - - - -0.176 1 230117_WJC_METTL3_WT_vs_EV_F03.17269.17269.2 1.07E-05 18-Dec K.VVDDEIYYFR[166.11].K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1327.6324 1.95 22693 17269 2 1327.638833 664.8235 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3435.6 - 676311 - - - 4.8545 - 2.404 0.452 - 519.6 1 2 0 0.0064 10 0 0 0 2.41E+07 1.24E+07 - - - 4.8258 1 230117_WJC_METTL3_WT_vs_EV_F03.17270.17270.2 1.12E-05 16-Sep R.TFTNVYWMK.V sp|Q9HBH1|DEFM_HUMAN 1 1188.5638 1.07 22694 17270 2 1188.566547 595.2892 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 8.26 3435.7 - 611093 - - - 2.3398 - 1.962 0.543 - 256.4 1 2 0 0.0028 9 0 0 0 8.07E+06 7.51E+06 - - - 5.0005 0.9534 230117_WJC_METTL3_WT_vs_EV_F03.17271.17271.2 0.535 12-Jun R.WLLDNVR[166.11].K "sp|Q14409|GLPK3_HUMAN,sp|P32189|GLPK_HUMAN,tr|H7C2A0|H7C2A0_HUMAN" 3 924.5057 1.43 22695 17271 2 924.509331 463.2601 Glycerol kinase 3 OS=Homo sapiens OX=9606 GN=GK3P PE=2 SV=2 5.84 3435.8 - 466309 - - - 3.9589 - 1.272 0.059 - 77 1 2 0 0.0037 7 0 0 0 1.61E+07 1.12E+07 - - - 0.2379 1 230117_WJC_METTL3_WT_vs_EV_F03.17272.17272.2 8.27E-06 18-Nov K.WVGVILDEAK.G "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1128.6179 3.01 22696 17272 2 1128.621179 565.3162 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3435.9 - 237277 - - - 2.8965 - 2.158 0.492 - 301.7 1 2 0 0.0033 10 0 0 0 1.62E+08 5.38E+07 - - - 4.8209 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.17274.17274.2 0.233 14-Aug R.AYILNLVK.Q sp|P50991|TCPD_HUMAN 1 932.5695 7.39 22697 17274 2 932.57255 467.292 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.63 3436.2 - 3.59E+07 - - - 3.2662 - 1.554 0.34 - 222.1 1 2 0 0.003 8 0 0 0 1.27E+09 1.72E+08 - - - 2.8808 0.9925 230117_WJC_METTL3_WT_vs_EV_F03.17287.17287.2 1.93E-05 22-Nov R.YVVGVLEAAGVR[166.11].Y sp|Q9H9S5|FKRP_HUMAN 1 1241.7007 0.4 22708 17287 2 1241.696821 621.8576 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 6 3437.6 - 623462 - - - -3.1578 - 2.117 0.239 - 299.5 1 2 0 -0.0039 12 0 0 0 5.49E+06 1.36E+07 - - - 2.7784 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.17288.17288.2 0.000337 22-Dec K.VLAGVLDSVDVR[166.11].L "sp|Q8NCH0|CHSTE_HUMAN,tr|H0YN65|H0YN65_HUMAN" 2 1251.7062 2.35 22709 17288 2 1251.706428 626.8604 Carbohydrate sulfotransferase 14 OS=Homo sapiens OX=9606 GN=CHST14 PE=1 SV=2 4.21 3437.7 - 553954 - - - 0.1646 - 2.206 0.343 - 610.6 1 2 0 0.0002 12 0 0 0 1.13E+07 4.81E+06 - - - 3.6561 0.9935 230117_WJC_METTL3_WT_vs_EV_F03.17291.17291.2 0.0983 16-Jul R.LLFYDEVSR.L sp|Q8N1F8|S11IP_HUMAN 1 1140.5815 4.97 22712 17291 2 1140.585258 571.298 Serine\threonine-protein kinase 11-interacting protein OS=Homo sapiens OX=9606 GN=STK11IP PE=1 SV=4 4.37 3438 - 179942 - - - 3.2729 - 1.33 0.205 - 93.8 1 2 0 0.0037 9 0 0 0 3.02E+06 6.07E+05 - - - 1.379 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.17296.17296.2 0.454 12-Aug K.TYDLLFK.L sp|P61026|RAB10_HUMAN 1 898.48 0.45 22715 17296 2 898.480795 450.2473 Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1 5.5 3438.6 - 520600 - - - 0.8626 - 1.603 0.278 - 214.7 1 2 0 0.0008 7 0 0 0 1.55E+07 3.46E+07 - - - 2.5892 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17303.17303.2 0.003 16-Oct R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 0.94 22720 17303 2 997.60701 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3439.4 - 3.34E+06 - - - 1.8474 - 2.137 0.386 - 229.9 1 2 0 0.0018 9 0 0 0 3.42E+09 3.62E+09 - - - 4.0884 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17304.17304.2 0.0011 18-Oct K.WVGVILDEAK[136.11].G "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1136.6321 2.97 22721 17304 2 1136.633484 569.3233 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3439.5 - 799350 - - - 1.2088 - 1.998 0.417 - 242.8 1 2 0 0.0014 10 0 0 0 1.60E+08 5.38E+07 - - - 4.0525 1 230117_WJC_METTL3_WT_vs_EV_F03.17305.17305.2 0.00779 13/18 K.VALAVSLNLR.T "sp|Q03426|KIME_HUMAN,tr|F5GXC0|F5GXC0_HUMAN,tr|F5H163|F5H163_HUMAN,tr|F5H092|F5H092_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|F5H368|F5H368_HUMAN,tr|A0A1W2PS16|A0A1W2PS16_HUMAN" 7 1054.6499 1.13 22722 17305 2 1054.653177 528.3322 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 9.72 3439.7 - 622104 - - - 3.1271 - 2.709 0.388 - 513.1 1 2 0 0.0033 10 0 0 0 6.65E+06 5.91E+06 - - - 4.6875 0.997 230117_WJC_METTL3_WT_vs_EV_F03.17306.17306.2 0.0645 14-Sep K.LFAELEIK.R "sp|O75937|DNJC8_HUMAN,tr|S4R3J5|S4R3J5_HUMAN" 2 961.5484 1.04 22723 17306 2 961.547923 481.7815 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.53 3439.8 - 444271 - - - -0.5314 - 1.58 0.214 - 146 1 2 0 -0.0005 8 0 0 0 5.11E+06 4.90E+06 - - - 2.001 1 230117_WJC_METTL3_WT_vs_EV_F03.17307.17307.2 1.01E-05 13/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 6.53 22724 17307 2 1484.90913 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3439.9 - 303455 - - - 0.8384 - 2.325 0.549 - 454 1 2 0 0.0012 15 0 0 0 3.27E+07 5.01E+06 - - - 5.1698 0.9829 230117_WJC_METTL3_WT_vs_EV_F03.17312.17312.2 0.699 12-Jun K.ELLTLIR.S "sp|Q15067|ACOX1_HUMAN,sp|Q92620|PRP16_HUMAN,tr|K7ENF1|K7ENF1_HUMAN,tr|K7ESC7|K7ESC7_HUMAN" 4 856.5382 1.59 22727 17312 2 856.536599 429.2764 Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3 6.1 3440.6 - 3.73E+06 - - - -1.8727 - 1.261 0.195 - 118.1 1 2 0 -0.0016 7 0 0 0 3.81E+07 2.39E+07 - - - 1.2156 1 230117_WJC_METTL3_WT_vs_EV_F03.17317.17317.2 8.64E-05 28-Oct R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 6.53 22732 17317 2 1494.919203 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3441.2 - 303139 - - - 2.0389 - 2.06 0.549 - 248 1 2 0 0.003 15 0 0 0 3.27E+07 5.01E+06 - - - 4.8718 0.9731 230117_WJC_METTL3_WT_vs_EV_F03.17319.17319.2 1.46 20-Jul K.ALVMYSNLDLK[136.11].T sp|O95900|TRUB2_HUMAN 1 1273.6832 1.32 22734 17319 2 1273.685838 637.8489 Mitochondrial mRNA pseudouridine synthase TRUB2 OS=Homo sapiens OX=9606 GN=TRUB2 PE=1 SV=1 5.88 3441.5 - 534643 - - - 2.1026 - 1.201 0.049 - 164.7 1 2 0 0.0027 11 0 0 0 1.35E+06 1.02E+06 - - - -0.1025 1 230117_WJC_METTL3_WT_vs_EV_F03.17321.17321.2 0.00431 16-Oct R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.94 22735 17321 2 989.592385 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3441.7 - 1.72E+07 - - - 1.4329 - 2.233 0.44 - 313.5 1 2 0 0.0014 9 0 0 0 3.43E+09 3.64E+09 - - - 4.6145 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17322.17322.2 0.0634 14-Oct K.IDLTLLNR[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 966.5738 1.14 22736 17322 2 966.57476 484.2942 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.84 3441.7 - 9.90E+06 - - - 1.0439 - 2.218 0.325 - 336.1 1 2 0 0.001 8 0 0 0 7.50E+07 6.57E+07 - - - 3.8437 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17323.17323.2 0.00293 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 8146.82 22737 17323 2 1006.571805 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3441.8 - 2.50E+06 - - - 1.8946 - 1.811 0.459 - 253.2 1 2 0 0.0019 9 0 0 0 7.61E+11 9.34E+07 - - - 4.1487 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.17324.17324.2 0.134 16-Oct K.VVLPC[160.03]NLLR[166.11].M "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1092.6353 2.24 22738 17324 2 1092.637599 547.3249 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 8.22 3441.9 - 2.42E+06 - - - 2.0986 - 1.469 0.336 - 404.8 1 2 0 0.0023 9 0 0 0 1.11E+08 4.97E+07 - - - 2.6346 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17328.17328.2 0.00573 18-Sep R.VVLPIEAPIR[166.11].M sp|P00403|COX2_HUMAN 1 1115.6942 1.63 22742 17328 2 1115.695634 558.8544 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 5.97 3442.4 - 418304 - - - 1.2853 - 1.893 0.436 - 326 1 2 0 0.0014 10 0 0 0 5.58E+08 3.43E+08 - - - 4.0422 0.972 230117_WJC_METTL3_WT_vs_EV_F03.17330.17330.2 0.166 18-Sep R.FSNLLGTVYR[166.11].R "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN,tr|C9J544|C9J544_HUMAN" 3 1178.6323 0.97 22744 17330 2 1178.637332 590.3234 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 8.75 3442.7 - 194232 - - - 4.2456 - 1.507 0.075 - 228.1 1 2 0 0.005 10 0 0 0 1.19E+07 1.23E+07 - - - 0.7382 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.17337.17337.2 0.000734 18-Jun R.VVLPIEAPIR.M sp|P00403|COX2_HUMAN 1 1105.6859 1.63 22749 17337 2 1105.68921 553.8502 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 5.97 3443.5 - 1.56E+06 - - - 2.9665 - 1.5 0.38 - 157.1 1 2 0 0.0033 10 0 0 0 5.58E+08 3.43E+08 - - - 2.9784 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.17338.17338.2 0.099 18-Oct K.IYVISLAEPR.L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1159.6601 1.97 22750 17338 2 1159.663049 580.8373 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3443.6 - 274028 - - - 2.5344 - 2.188 0.392 - 372.8 1 2 0 0.0029 10 0 0 0 1.73E+08 8.77E+07 - - - 4.1209 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.17340.17340.2 0.0894 14-Oct K.IDLTLLNR.L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 956.5655 1.2 22751 17340 2 956.566185 479.29 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.84 3443.9 - 5.66E+06 - - - 0.736 - 2.15 0.29 - 331.8 1 2 0 0.0007 8 0 0 0 7.43E+07 6.21E+07 - - - 3.4913 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.17350.17350.2 0.043 18-Aug R.LLFNDVQTLK[136.11].D "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1197.6849 1.06 22758 17350 2 1197.686261 599.8497 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.84 3444.9 - 751089 - - - 1.1581 - 1.75 0.24 - 121.4 2 2 0 0.0014 10 0 0 0 2.69E+07 2.53E+07 - - - 2.2408 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.17352.17352.2 0.025 14-Jul K.FYFEELGK[136.11].Y sp|Q10471|GALT2_HUMAN 1 1039.5106 0.89 22760 17352 2 1039.511314 520.7626 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3445.2 - 797032 - - - 0.6888 - 1.188 0.388 - 135.9 1 2 0 0.0007 8 0 0 0 3.62E+07 4.05E+07 - - - 2.4261 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.17354.17354.2 0.000289 20-Oct R.FLPEFAGTQLK.L sp|Q9UBZ4|APEX2_HUMAN 1 1249.6707 1.3 22762 17354 2 1249.671536 625.8426 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 6 3445.5 - 436398 - - - 0.6898 - 1.686 0.37 - 325.8 1 2 0 0.0009 11 0 0 0 5.75E+07 4.42E+07 - - - 3.1867 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.17361.17361.2 0.0243 20-Aug R.FLPEFAGTQLK[136.11].L sp|Q9UBZ4|APEX2_HUMAN 1 1257.6849 1.3 22767 17361 2 1257.685114 629.8497 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 6 3446.4 - 2.58E+06 - - - 0.1908 - 1.411 0.277 - 180.9 1 2 0 0.0002 11 0 0 0 5.75E+07 4.42E+07 - - - 2.0183 0.9926 230117_WJC_METTL3_WT_vs_EV_F03.17365.17365.2 0.0261 14-Jul K.FYFEELGK.Y sp|Q10471|GALT2_HUMAN 1 1031.4964 0.72 22771 17365 2 1031.493077 516.7555 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3446.8 - 2.48E+06 - - - -3.2196 - 1.479 0.354 - 152.8 1 2 0 -0.0033 8 0 0 0 2.87E+07 4.00E+07 - - - 2.8349 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.17376.17376.2 0.00135 22-Dec R.LNVGGTYFLTTR[166.11].Q "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1350.7171 0.47 22779 17376 2 1350.716013 676.3658 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3448.2 - 1.69E+06 - - - -0.8203 - 2.046 0.488 - 445.8 1 2 0 -0.0011 12 0 0 0 5.65E+06 1.20E+07 - - - 4.5286 1 230117_WJC_METTL3_WT_vs_EV_F03.17378.17378.2 3.21E-05 22-Oct R.LNVGGTYFLTTR.Q "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1340.7089 0.47 22781 17378 2 1340.701914 671.3617 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3448.4 - 1.11E+06 - - - -5.1741 - 2.318 0.475 - 309.1 1 2 0 -0.0069 12 0 0 0 5.65E+06 1.20E+07 - - - 4.7592 1 230117_WJC_METTL3_WT_vs_EV_F03.17383.17383.2 0.0116 18-Dec N.PEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1087.5662 999 22784 17383 2 1087.564693 544.7904 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.43 3449 - 1.86E+06 - - - -1.3939 - 2.488 0.463 - 640.2 1 1 0 -0.0015 10 0 0 0 9.35E+07 0.00E+00 - - - 5.0045 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.17386.17386.2 2.72E-05 20-Nov R.LYPVLQQSLVR.A sp|Q5RKV6|EXOS6_HUMAN 1 1314.766 1 22786 17386 2 1314.765685 658.3903 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.75 3449.3 - 367687 - - - -0.2183 - 1.798 0.512 - 495 1 2 0 -0.0003 11 0 0 0 1.25E+07 1.26E+07 - - - 4.4096 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.17402.17402.2 0.00431 18-Sep K.IYVISLAEPR[166.11].L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1169.6684 1.97 22796 17402 2 1169.66931 585.8415 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3451.1 - 4.68E+06 - - - 0.7951 - 1.721 0.35 - 189.2 1 2 0 0.0009 10 0 0 0 1.73E+08 8.77E+07 - - - 3.1412 0.8504 230117_WJC_METTL3_WT_vs_EV_F03.17428.17428.2 0.118 14-Oct Y.LDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 843.5066 999 22812 17428 2 843.506503 422.7606 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.84 3453.7 - 7.28E+06 - - - -0.0782 - 2.028 0.115 - 312.5 1 1 0 -0.0001 8 0 0 0 3.14E+08 0.00E+00 - - - 2.0228 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17439.17439.2 0.00391 16-Nov K.IAFAITAIK.G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 946.5852 1.19 22815 17439 2 946.5868 474.2999 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3455.1 - 5.58E+06 - - - 1.7389 - 2.294 0.357 - 318.7 1 2 0 0.0016 9 0 0 0 1.44E+10 1.21E+10 - - - 4.0794 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.17440.17440.2 0.0691 14-Aug R.GIFEPFGK.L "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 893.4647 1.06 22816 17440 2 893.464855 447.7396 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 6 3455.2 - 4.57E+06 - - - 0.169 - 1.41 0.273 - 195.8 1 2 0 0.0002 8 0 0 0 1.59E+08 1.50E+08 - - - 2.0936 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.17444.17444.2 0.32 16-Oct K.IAFAITAIK[136.11].G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 954.5994 1.19 22817 17444 2 954.602707 478.307 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3455.8 - 1.49E+07 - - - 3.5125 - 2.138 0.251 - 240.9 1 2 0 0.0034 9 0 0 0 1.44E+10 1.21E+10 - - - 3.0922 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.17456.17456.2 0.000175 20-Dec R.MGPGIGAILER[166.11].S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1122.6095 2.59 22819 17456 2 1122.607921 562.312 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.75 3457.4 - 2.81E+06 - - - -1.3923 - 2.232 0.441 - 474 1 2 0 -0.0016 11 0 0 0 2.47E+08 9.54E+07 - - - 4.4698 0.9958 230117_WJC_METTL3_WT_vs_EV_F03.17466.17466.2 0.0563 12-Jul K.ELEFYLR.K "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 968.4967 0.91 22820 17466 2 968.499214 485.2556 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.53 3459.1 - 2.13E+07 - - - 2.5617 - 1.381 0.179 - 347.6 1 2 0 0.0025 7 0 0 0 1.10E+09 1.21E+09 - - - 1.3851 0.999 230117_WJC_METTL3_WT_vs_EV_F03.17469.17469.2 0.0941 18-Jul R.LGLPGEVFGR.S sp|O95409|ZIC2_HUMAN 1 1043.5764 2.46 22821 17469 2 1043.577848 522.7955 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 6 3459.4 - 4.21E+06 - - - 1.4067 - 1.481 0.307 - 112.9 1 2 0 0.0015 10 0 0 0 4.50E+08 1.83E+08 - - - 2.4042 0.9934 230117_WJC_METTL3_WT_vs_EV_F03.17473.17473.2 0.213 16-Aug K.SALLALGLK.C sp|Q12874|SF3A3_HUMAN 1 884.5695 3.42 22822 17473 2 884.566559 443.292 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3460 - 2.98E+06 - - - -3.3293 - 1.79 0.318 - 205.8 1 2 0 -0.0029 9 0 0 0 7.96E+08 2.33E+08 - - - 3.0732 1 230117_WJC_METTL3_WT_vs_EV_F03.17477.17477.2 3.37E-06 14/20 R.MGPGIGAILER.S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1112.6012 2.6 22824 17477 2 1112.598528 557.3079 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.75 3460.5 - 4.33E+06 - - - -2.4142 - 2.399 0.531 - 675.7 1 2 0 -0.0027 11 0 0 0 2.48E+08 9.54E+07 - - - 5.3293 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17479.17479.2 0.002 18-Nov R.LGLPGEVFGR[166.11].S sp|O95409|ZIC2_HUMAN 1 1053.5847 2.46 22825 17479 2 1053.585742 527.7996 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 6 3460.7 - 2.86E+06 - - - 1.0365 - 1.993 0.417 - 316.2 1 2 0 0.0011 10 0 0 0 4.49E+08 1.83E+08 - - - 4.0456 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.17487.17487.2 0.0221 16-Oct K.SALLALGLK[136.11].C sp|Q12874|SF3A3_HUMAN 1 892.5837 3.45 22828 17487 2 892.582946 447.2991 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3461.7 - 2.49E+06 - - - -0.8492 - 1.954 0.292 - 339.8 1 2 0 -0.0008 9 0 0 0 7.95E+08 2.31E+08 - - - 3.1355 0.9908 230117_WJC_METTL3_WT_vs_EV_F03.17496.17496.2 0.0597 16-Oct K.YPQLLPGIR[166.11].G sp|P23526|SAHH_HUMAN 1 1065.621 0.86 22831 17496 2 1065.617469 533.8178 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 8.75 3463 - 0 - - - -3.3464 - 1.605 0.306 - 327.2 1 2 0 -0.0036 9 0 0 0 4.15E+07 4.84E+07 - - - 2.6688 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.17505.17505.2 0.0153 14-Oct K.IIDFGLAR.R "sp|Q86YV6|MYLK4_HUMAN,sp|Q32MK0|MYLK3_HUMAN,sp|Q9H1R3|MYLK2_HUMAN,sp|P53778|MK12_HUMAN,sp|O15264|MK13_HUMAN,sp|P45983|MK08_HUMAN,sp|Q16539|MK14_HUMAN,sp|P45984|MK09_HUMAN,sp|Q15759|MK11_HUMAN,sp|P53779|MK10_HUMAN,sp|Q15746|MYLK_HUMAN,tr|A0A286YFD7|A0A286YFD7_HUMAN,tr|A0A286YES0|A0A286YES0_HUMAN,tr|A0A286YEQ0|A0A286YEQ0_HUMAN,tr|A0A286YEX7|A0A286YEX7_HUMAN,tr|A0A286YFC0|A0A286YFC0_HUMAN,tr|B5MDL5|B5MDL5_HUMAN,tr|A0A286YES9|A0A286YES9_HUMAN,tr|A0A286YF97|A0A286YF97_HUMAN,tr|D6RCB1|D6RCB1_HUMAN,tr|A0A286YF19|A0A286YF19_HUMAN,tr|A0A286YFN2|A0A286YFN2_HUMAN,tr|D6RJF9|D6RJF9_HUMAN,tr|A0A286YEY0|A0A286YEY0_HUMAN,tr|Q5R3E6|Q5R3E6_HUMAN,tr|A0A286YEV8|A0A286YEV8_HUMAN,tr|B4E0K5|B4E0K5_HUMAN,tr|A0A286YF85|A0A286YF85_HUMAN,tr|A0A286YFI3|A0A286YFI3_HUMAN,tr|F8W9R5|F8W9R5_HUMAN,tr|A0A2R8Y4U5|A0A2R8Y4U5_HUMAN,tr|A0A286YFM6|A0A286YFM6_HUMAN,tr|A0A286YEV3|A0A286YEV3_HUMAN,tr|A0A286YF83|A0A286YF83_HUMAN,tr|A0A286YFJ6|A0A286YFJ6_HUMAN,tr|A0A286YF62|A0A286YF62_HUMAN,tr|A0A286YF02|A0A286YF02_HUMAN,tr|J3KNK1|J3KNK1_HUMAN,tr|A0A286YEQ7|A0A286YEQ7_HUMAN,tr|A0A286YFJ4|A0A286YFJ4_HUMAN,tr|A0A1W2PPZ3|A0A1W2PPZ3_HUMAN,tr|A0A286YEN5|A0A286YEN5_HUMAN,tr|A0A286YFA6|A0A286YFA6_HUMAN,tr|A0A1P0B7D2|A0A1P0B7D2_HUMAN,tr|A0A1W2PRF2|A0A1W2PRF2_HUMAN,tr|D7R525|D7R525_HUMAN,tr|A0A286YF35|A0A286YF35_HUMAN,tr|A0A286YFB6|A0A286YFB6_HUMAN,tr|A0A286YFE2|A0A286YFE2_HUMAN,tr|A0A286YEW9|A0A286YEW9_HUMAN,tr|E7EX54|E7EX54_HUMAN" 51 903.5178 3.14 22835 17505 2 903.518603 452.7662 Myosin light chain kinase family member 4 OS=Homo sapiens OX=9606 GN=MYLK4 PE=1 SV=2 5.84 3464.2 - 1.70E+06 - - - 0.8865 - 1.987 0.054 - 261.2 1 2 0 0.0008 8 0 0 0 7.90E+07 2.52E+07 - - - 1.5104 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17510.17510.2 0.00034 18-Oct R.FQSLGVAFYR[166.11].G "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1196.6218 1.71 22838 17510 2 1196.623063 599.3182 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 8.75 3464.7 - 2.49E+06 - - - 1.0856 - 2.112 0.4 - 289.9 1 2 0 0.0013 10 0 0 0 1.38E+08 8.08E+07 - - - 4.0819 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.17511.17511.2 0.0485 16-Jul K.ALQFLEEVK.V sp|P40227|TCPZ_HUMAN 1 1075.5914 86.71 22839 17511 2 1075.592755 538.803 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 3464.8 - 2.12E+06 - - - 1.296 - 1.671 0.198 - 144.5 2 2 0 0.0014 9 0 0 0 8.49E+07 9.79E+05 - - - 1.8539 0.9759 230117_WJC_METTL3_WT_vs_EV_F03.17512.17512.2 2.79 14-Jul K.GLGILSLK[136.11].Q sp|Q92616|GCN1_HUMAN 1 807.5309 0.5 22840 17512 2 807.529693 404.7727 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.75 3465 - 1.36E+06 - - - -1.5442 - 1.349 0.115 - 137.3 1 2 0 -0.0012 8 0 0 0 3.57E+07 7.16E+07 - - - 0.7929 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.17515.17515.2 0.000181 20-Dec K.FSPAGPILSIR[166.11].L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1166.6687 1.03 22841 17515 2 1166.675551 584.3416 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3465.4 - 2.20E+06 - - - 5.8603 - 1.992 0.373 - 543 1 2 0 0.0068 11 0 0 0 1.36E+09 1.32E+09 - - - 3.6581 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.17516.17516.2 0.000395 20-Oct K.FSPAGPILSIR.L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1156.6604 1.03 22842 17516 2 1156.663141 579.3375 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3465.6 - 2.29E+06 - - - 2.3317 - 1.859 0.333 - 405.5 1 2 0 0.0027 11 0 0 0 1.36E+09 1.32E+09 - - - 3.177 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.17527.17527.2 6.31E-05 20-Oct K.VLADLAIYEPK[136.11].T sp|Q9BYC9|RM20_HUMAN 1 1238.7002 1.08 22844 17527 2 1238.702608 620.3574 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3467.3 - 1.49E+06 - - - 1.952 - 2.013 0.274 - 192.1 1 2 0 0.0024 11 0 0 0 5.63E+07 5.23E+07 - - - 2.9567 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.17530.17530.2 0.00465 14-Jul R.GLFIIDGK[136.11].G sp|P32119|PRDX2_HUMAN 1 869.5102 2.45 22846 17530 2 869.509477 435.7624 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3467.6 - 1.06E+06 - - - -0.8361 - 1.448 0.343 - 183.4 1 2 0 -0.0007 8 0 0 0 7.60E+08 3.10E+08 - - - 2.6906 0.9958 230117_WJC_METTL3_WT_vs_EV_F03.17531.17531.2 0.0701 14-Sep K.IIDFGLAR[166.11].R "sp|Q86YV6|MYLK4_HUMAN,sp|Q32MK0|MYLK3_HUMAN,sp|Q9H1R3|MYLK2_HUMAN,sp|P53778|MK12_HUMAN,sp|O15264|MK13_HUMAN,sp|P45983|MK08_HUMAN,sp|Q16539|MK14_HUMAN,sp|P45984|MK09_HUMAN,sp|Q15759|MK11_HUMAN,sp|P53779|MK10_HUMAN,sp|Q15746|MYLK_HUMAN,tr|A0A286YFD7|A0A286YFD7_HUMAN,tr|A0A286YES0|A0A286YES0_HUMAN,tr|A0A286YEQ0|A0A286YEQ0_HUMAN,tr|A0A286YEX7|A0A286YEX7_HUMAN,tr|A0A286YFC0|A0A286YFC0_HUMAN,tr|B5MDL5|B5MDL5_HUMAN,tr|A0A286YES9|A0A286YES9_HUMAN,tr|A0A286YF97|A0A286YF97_HUMAN,tr|D6RCB1|D6RCB1_HUMAN,tr|A0A286YF19|A0A286YF19_HUMAN,tr|A0A286YFN2|A0A286YFN2_HUMAN,tr|D6RJF9|D6RJF9_HUMAN,tr|A0A286YEY0|A0A286YEY0_HUMAN,tr|Q5R3E6|Q5R3E6_HUMAN,tr|A0A286YEV8|A0A286YEV8_HUMAN,tr|B4E0K5|B4E0K5_HUMAN,tr|A0A286YF85|A0A286YF85_HUMAN,tr|A0A286YFI3|A0A286YFI3_HUMAN,tr|F8W9R5|F8W9R5_HUMAN,tr|A0A2R8Y4U5|A0A2R8Y4U5_HUMAN,tr|A0A286YFM6|A0A286YFM6_HUMAN,tr|A0A286YEV3|A0A286YEV3_HUMAN,tr|A0A286YF83|A0A286YF83_HUMAN,tr|A0A286YFJ6|A0A286YFJ6_HUMAN,tr|A0A286YF62|A0A286YF62_HUMAN,tr|A0A286YF02|A0A286YF02_HUMAN,tr|J3KNK1|J3KNK1_HUMAN,tr|A0A286YEQ7|A0A286YEQ7_HUMAN,tr|A0A286YFJ4|A0A286YFJ4_HUMAN,tr|A0A1W2PPZ3|A0A1W2PPZ3_HUMAN,tr|A0A286YEN5|A0A286YEN5_HUMAN,tr|A0A286YFA6|A0A286YFA6_HUMAN,tr|A0A1P0B7D2|A0A1P0B7D2_HUMAN,tr|A0A1W2PRF2|A0A1W2PRF2_HUMAN,tr|D7R525|D7R525_HUMAN,tr|A0A286YF35|A0A286YF35_HUMAN,tr|A0A286YFB6|A0A286YFB6_HUMAN,tr|A0A286YFE2|A0A286YFE2_HUMAN,tr|A0A286YEW9|A0A286YEW9_HUMAN,tr|E7EX54|E7EX54_HUMAN" 51 913.5261 3.13 22847 17531 2 913.529109 457.7703 Myosin light chain kinase family member 4 OS=Homo sapiens OX=9606 GN=MYLK4 PE=1 SV=2 5.84 3467.7 - 1.52E+06 - - - 3.3245 - 1.89 0.111 - 208.9 1 2 0 0.003 8 0 0 0 7.88E+07 2.52E+07 - - - 1.7798 0.9917 230117_WJC_METTL3_WT_vs_EV_F03.17534.17534.2 0.02 14-Jul R.GLFIIDGK.G sp|P32119|PRDX2_HUMAN 1 861.496 2.45 22848 17534 2 861.493044 431.7553 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3468.1 - 4.73E+06 - - - -3.4359 - 1.617 0.32 - 227.7 1 2 0 -0.003 8 0 0 0 7.62E+08 3.10E+08 - - - 2.853 1 230117_WJC_METTL3_WT_vs_EV_F03.17536.17536.2 3.55E-06 13/18 K.VGDQILLAIK.G sp|Q6P1L8|RM14_HUMAN 1 1068.6543 1.61 22850 17536 2 1068.649209 535.3344 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3468.4 - 2.65E+06 - - - -4.7602 - 2.544 0.51 - 566.6 1 2 0 -0.0051 10 0 0 0 2.05E+08 1.27E+08 - - - 5.4126 1 230117_WJC_METTL3_WT_vs_EV_F03.17539.17539.2 3.05E-05 13/20 K.VYGAILVAVER.L sp|Q9Y6J9|TAF6L_HUMAN 1 1188.6867 1.03 22851 17539 2 1188.687478 595.3506 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 5.97 3468.8 - 4.07E+06 - - - 0.689 - 2.501 0.533 - 587.5 1 2 0 0.0008 11 0 0 0 8.61E+07 8.38E+07 - - - 5.4573 0.9633 230117_WJC_METTL3_WT_vs_EV_F03.17541.17541.2 0.00322 18-Nov D.TLDNDIMLIK.L "sp|P35030|TRY3_HUMAN,tr|A0A7P0MNE9|A0A7P0MNE9_HUMAN" 2 1174.6268 35.75 22853 17541 2 1174.630227 588.3207 Trypsin-3 OS=Homo sapiens OX=9606 GN=PRSS3 PE=1 SV=2 4.21 3468.9 - 5.35E+06 - - - 2.9507 - 2.061 0.451 - 251 1 1 0 0.0035 10 0 0 0 1.34E+08 3.76E+06 - - - 4.3896 1 230117_WJC_METTL3_WT_vs_EV_F03.17542.17542.2 2.62E-05 18-Oct K.LGDDIDLIVR[166.11].C sp|O15371|EIF3D_HUMAN 1 1137.6269 1.1 22854 17542 2 1137.618255 569.8207 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3469.1 - 1.65E+06 - - - -7.6071 - 2.432 0.461 - 246.5 1 2 0 -0.0087 10 0 0 0 7.55E+08 6.87E+08 - - - 4.9239 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.17543.17543.2 0.00498 20-Aug K.LGNPIVPLNIR[166.11].L sp|P78527|PRKDC_HUMAN 1 1214.7375 0.96 22855 17543 2 1214.737597 608.376 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3469.2 - 1.12E+06 - - - 0.1111 - 1.526 0.393 - 190.4 1 2 0 0.0001 11 0 0 0 1.09E+07 1.14E+07 - - - 3.087 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17547.17547.2 6.84E-05 18-Dec K.VGDQILLAIK[136.11].G sp|Q6P1L8|RM14_HUMAN 1 1076.6685 1.61 22857 17547 2 1076.668938 539.3415 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3469.7 - 3.60E+06 - - - 0.4105 - 2.243 0.426 - 407 1 2 0 0.0004 10 0 0 0 2.05E+08 1.27E+08 - - - 4.4422 1 230117_WJC_METTL3_WT_vs_EV_F03.17548.17548.2 3.44E-07 18-Dec K.LGDDIDLIVR.C sp|O15371|EIF3D_HUMAN 1 1127.6186 1.1 22858 17548 2 1127.612576 564.8166 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3469.7 - 2.05E+06 - - - -5.3768 - 2.609 0.491 - 435.3 1 2 0 -0.0061 10 0 0 0 7.56E+08 6.88E+08 - - - 5.3424 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.17549.17549.2 0.00698 16-Oct R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 0.84 22859 17549 2 997.608049 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3469.8 - 5.11E+06 - - - 2.8889 - 2.257 0.369 - 249 1 2 0 0.0029 9 0 0 0 3.84E+08 4.57E+08 - - - 4.1206 1 230117_WJC_METTL3_WT_vs_EV_F03.17551.17551.2 1.22E-06 14/26 R.GLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1541.7726 - 22861 17551 2 1541.771475 771.8936 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3470 - 1.83E+06 - - - -0.7122 - 2.304 0.525 - 174.6 1 1 0 -0.0011 14 0 0 0 - - - - - 5.0128 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.17553.17553.2 0.0147 18-Aug K.LLYPLQEVER[166.11].F "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 1268.7004 1.18 22863 17553 2 1268.704569 635.3575 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.53 3470.3 - 662016 - - - 3.2797 - 1.443 0.336 - 198.4 1 2 0 0.0042 10 0 0 0 1.18E+07 1.00E+07 - - - 2.545 1 230117_WJC_METTL3_WT_vs_EV_F03.17555.17555.2 1.53E-05 15/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 10.18 22864 17555 2 1484.911508 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3470.6 - 1.75E+06 - - - 2.4399 - 2.464 0.572 - 525 1 2 0 0.0036 15 0 0 0 9.64E+07 9.47E+06 - - - 5.4817 0.9958 230117_WJC_METTL3_WT_vs_EV_F03.17558.17558.2 0.772 12-Jul K.SLDIFIK.A sp|Q9H583|HEAT1_HUMAN 1 834.4851 0.39 22866 17558 2 834.488252 418.2498 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.55 3470.8 - 1.22E+06 - - - 3.7712 - 1.48 0.238 - 176.6 1 2 0 0.0031 7 0 0 0 3.16E+07 8.15E+07 - - - 2.0401 0.8976 230117_WJC_METTL3_WT_vs_EV_F03.17559.17559.2 5.15 12-Jun K.FIPEFIR.K "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|A0A804HIK9|A0A804HIK9_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 5 920.512 10.33 22867 17559 2 920.516003 461.2633 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6 3471 - 1.44E+06 - - - 4.3606 - 1.067 0.084 - 126.9 1 2 0 0.004 7 0 0 0 1.63E+09 1.58E+08 - - - -0.1344 0.994 230117_WJC_METTL3_WT_vs_EV_F03.17560.17560.2 0.00067 14-Sep R.GPIAFWAR[166.11].R "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H909|Q5H909_HUMAN" 2 926.5002 1.76 22868 17560 2 926.505136 464.2574 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 9.75 3471.1 - 1.22E+06 - - - 5.3362 - 1.556 0.33 - 234 1 2 0 0.0049 8 0 0 0 5.98E+07 3.40E+07 - - - 2.8102 0.9495 230117_WJC_METTL3_WT_vs_EV_F03.17561.17561.2 4.51E-05 16-Dec S.PAGPILSIR[166.11].L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 932.5683 0.05 22869 17561 2 932.5693 467.2914 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 10.18 3471.2 - 1.01E+06 - - - 1.1023 - 2.369 0.178 - 423.6 1 1 0 0.001 9 0 0 0 1.42E+07 2.72E+08 - - - 2.8506 0.9952 230117_WJC_METTL3_WT_vs_EV_F03.17567.17567.2 0.107 16-Aug R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.85 22872 17567 2 989.594334 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3471.9 - 3.49E+06 - - - 3.4024 - 1.883 0.113 - 180.7 1 2 0 0.0034 9 0 0 0 3.68E+08 4.35E+08 - - - 1.7055 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.17569.17569.2 0.00297 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 8146.81 22873 17569 2 1006.572328 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3472.2 - 1.33E+09 - - - 2.4141 - 1.952 0.467 - 256.3 1 2 0 0.0024 9 0 0 0 7.61E+11 9.34E+07 - - - 4.4245 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.17571.17571.2 0.287 18-Oct K.ALLAEGVILR.R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1053.6546 1.34 22875 17571 2 1053.656818 527.8346 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3472.3 - 1.73E+06 - - - 2.0766 - 1.993 0.165 - 253.9 1 2 0 0.0022 10 0 0 0 5.12E+08 3.82E+08 - - - 2.184 0.9851 230117_WJC_METTL3_WT_vs_EV_F03.17572.17572.2 0.712 12-Jun R.IIFDDFR[166.11].E sp|P46977|STT3A_HUMAN 1 934.4788 1.13 22876 17572 2 934.480908 468.2467 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.21 3472.4 - 878498 - - - 2.2686 - 1.05 0.155 - 81.2 1 2 0 0.0021 7 0 0 0 2.68E+08 2.37E+08 - - - 0.3398 0.9967 230117_WJC_METTL3_WT_vs_EV_F03.17577.17577.2 1.27 18-Dec K.ALLAEGVILR[166.11].R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1063.6629 1.34 22879 17577 2 1063.66297 532.8387 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3473 - 2.92E+06 - - - 0.0658 - 1.882 0.108 - 633.9 1 2 0 0.0001 10 0 0 0 5.12E+08 3.82E+08 - - - 1.6037 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.17579.17579.2 0.00309 18-Nov R.IAEFAFEYAR[166.11].N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1225.6007 2.56 22881 17579 2 1225.603936 613.8076 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3473.3 - 611031 - - - 2.6452 - 2.211 0.188 - 456.2 1 2 0 0.0032 10 0 0 0 7.25E+07 2.83E+07 - - - 2.6433 0.9072 230117_WJC_METTL3_WT_vs_EV_F03.17582.17582.2 0.377 12-May R.LFLEFER[166.11].K "sp|O43663|PRC1_HUMAN,sp|Q96I25|SPF45_HUMAN,tr|H0YL53|H0YL53_HUMAN" 3 962.5101 0.83 22882 17582 2 962.514859 482.2623 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 3473.7 - 1.36E+06 - - - 4.9568 - 1.326 0.073 - 67.3 4 2 0 0.0048 7 0 0 0 6.26E+07 7.58E+07 - - - 0.2038 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.17583.17583.2 0.0536 18-Sep R.IAEFAFEYAR.N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1215.5924 2.57 22883 17583 2 1215.596739 608.8035 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3473.8 - 1.48E+06 - - - 3.5497 - 2.219 0.27 - 284.1 1 2 0 0.0043 10 0 0 0 7.26E+07 2.83E+07 - - - 3.2587 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.17584.17584.2 0.166 20-Dec K.VLADLAIYEPK.T sp|Q9BYC9|RM20_HUMAN 1 1230.686 1.08 22884 17584 2 1230.686015 616.3503 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3473.9 - 1.57E+06 - - - 0.0203 - 1.912 0.24 - 231.8 1 2 0 0 11 0 0 0 5.63E+07 5.23E+07 - - - 2.567 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.17585.17585.2 0.618 12-Jul K.ITWSIIR[166.11].E sp|P38606|VATA_HUMAN 1 897.5312 0.91 22885 17585 2 897.531365 449.7729 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 9.75 3474 - 1.41E+06 - - - 0.2306 - 1.556 0.163 - 139.9 1 2 0 0.0002 7 0 0 0 2.33E+07 2.56E+07 - - - 1.6457 1 230117_WJC_METTL3_WT_vs_EV_F03.17586.17586.2 0.000483 20-Nov R.LLYC[160.03]TTGVLLR.R "sp|Q6P158|DHX57_HUMAN,sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 3 1307.7271 0.58 22886 17586 2 1307.729965 654.8708 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 8.22 3474.2 - 722372 - - - 2.1572 - 2.32 0.49 - 536.5 1 2 0 0.0028 11 0 0 0 1.32E+07 2.27E+07 - - - 4.9359 0.9919 230117_WJC_METTL3_WT_vs_EV_F03.17591.17591.2 2.38 14-Aug R.NLLTGLVR[166.11].H "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 894.5526 1.26 22889 17591 2 894.551637 448.2836 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 9.75 3474.7 - 2.16E+06 - - - -1.1 - 1.607 0.129 - 227.4 1 2 0 -0.001 8 0 0 0 2.21E+08 1.75E+08 - - - 1.4242 0.9048 230117_WJC_METTL3_WT_vs_EV_F03.17593.17593.2 1.34 14-Jun R.NLLTGLVR.H "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 884.5444 1.09 22891 17593 2 884.540848 443.2795 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 9.75 3474.9 - 2.28E+06 - - - -3.9602 - 1.195 0.19 - 126.4 2 2 0 -0.0035 8 0 0 0 2.26E+08 2.08E+08 - - - 0.8461 0.9436 230117_WJC_METTL3_WT_vs_EV_F03.17596.17596.2 0.0102 16-Jul R.ITELMQVLK[136.11].D "sp|P28288|ABCD3_HUMAN,tr|A0A3B3ITW3|A0A3B3ITW3_HUMAN" 2 1081.6297 0.61 22894 17596 2 1081.637422 541.8221 ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3 PE=1 SV=1 6 3475.2 - 681248 - - - 7.1688 - 1.712 0.148 - 78.6 1 2 0 0.0078 9 0 0 0 5.63E+06 9.30E+06 - - - 1.6872 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.17602.17602.2 0.154 16-Aug R.LNVLANVIR[166.11].K "sp|Q02218|ODO1_HUMAN,sp|Q9ULD0|OGDHL_HUMAN,tr|E9PFG7|E9PFG7_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|A0A0D9SFS3|A0A0D9SFS3_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 6 1020.6319 0.9 22898 17602 2 1020.631233 511.3232 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 9.75 3476 - 501874 - - - -0.6868 - 1.768 0.226 - 176.2 1 2 0 -0.0007 9 0 0 0 1.95E+07 2.18E+07 - - - 2.3586 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.17605.17605.2 0.00138 18-Oct R.LPLLAVC[160.03]DYK.Q "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1190.6369 0.6 22899 17605 2 1190.636367 596.3257 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.83 3476.4 - 528179 - - - -0.4745 - 1.719 0.37 - 334.9 1 2 0 -0.0006 10 0 0 0 1.61E+07 2.68E+07 - - - 3.2858 0.986 230117_WJC_METTL3_WT_vs_EV_F03.17606.17606.2 0.459 12-Jul K.DFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 834.46 0.8 22900 17606 2 834.458389 418.2373 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.84 3476.5 - 495113 - - - -1.8743 - 1.375 0.18 - 148.3 1 2 0 -0.0016 7 0 0 0 1.59E+07 1.99E+07 - - - 1.379 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.17611.17611.2 0.0221 14-Jul R.LLNVWQVR.S "sp|Q15061|WDR43_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 2 1026.5974 1.05 22903 17611 2 1026.596689 514.306 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 9.75 3477.1 - 2.38E+06 - - - -0.7413 - 1.607 0.314 - 157.9 1 2 0 -0.0008 8 0 0 0 1.01E+08 9.66E+07 - - - 2.7906 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.17613.17613.2 0.00101 14-Jul K.GFGFGLVK[136.11].L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 831.4734 1.21 22905 17613 2 831.472252 416.744 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3477.4 - 841261 - - - -1.4107 - 1.412 0.453 - 153.5 1 2 0 -0.0012 8 0 0 0 5.27E+08 4.36E+08 - - - 3.427 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.17616.17616.2 0.0017 18-Sep K.ILETLYTLGK.A "sp|Q5W0V3|FHI2A_HUMAN,tr|Q5W0V4|Q5W0V4_HUMAN" 2 1149.6645 999 22908 17616 2 1149.66477 575.8395 FHF complex subunit HOOK interacting protein 2A OS=Homo sapiens OX=9606 GN=FHIP2A PE=1 SV=1 6 3477.8 - 373018 - - - 0.2122 - 1.656 0.338 - 158.7 1 2 0 0.0002 10 0 0 0 1.06E+07 0.00E+00 - - - 2.9453 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.17621.17621.2 0.0213 14-Aug K.LMWIPDTK.G sp|P61962|DCAF7_HUMAN 1 1002.5208 1.86 22911 17621 2 1002.523884 502.2677 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.84 3478.3 - 1.68E+06 - - - 3.0373 - 1.595 0.327 - 273 1 2 0 0.003 8 0 0 0 1.23E+08 6.63E+07 - - - 2.8633 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.17624.17624.2 2.10E-06 13/22 K.TPAILYTYSGLR.N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1353.7293 2.72 22913 17624 2 1353.728557 677.8719 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3478.7 - 936952 - - - -0.5134 - 2.763 0.323 - 652.8 1 2 0 -0.0007 12 0 0 0 2.41E+07 8.85E+06 - - - 4.1006 0.9952 230117_WJC_METTL3_WT_vs_EV_F03.17626.17626.3 1.29E-05 19/36 K.LPPVLVLHLK[136.11].R "sp|Q14694|UBP10_HUMAN,tr|H3BQP1|H3BQP1_HUMAN" 2 1135.7573 0.001 22914 17626 3 1136.760964 379.593 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.76 3478.9 - 480594 - - - 883.739 - 2.483 0.448 - 381.2 1 2 0 1.0037 10 0 0 0 0.00E+00 1.13E+06 - - - 5.9128 0.9926 230117_WJC_METTL3_WT_vs_EV_F03.17629.17629.2 0.043 20-Oct R.ELLIIGGVAAR[166.11].D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1120.6844 1.15 22916 17629 2 1120.691582 561.3495 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3479.2 - 404717 - - - 6.4407 - 2.268 0.311 - 233.6 1 2 0 0.0072 11 0 0 0 5.12E+08 4.45E+08 - - - 3.5511 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.17630.17630.2 0.000179 22-Nov K.LPVGTTATLYFR.D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1337.7343 1.21 22917 17630 2 1337.740312 669.8744 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3479.4 - 714569 - - - 4.4665 - 1.983 0.405 - 356.8 1 2 0 0.006 12 0 0 0 2.98E+07 2.47E+07 - - - 3.8318 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.17633.17633.2 0.143 20-Sep R.ELLIIGGVAAR.D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1110.6761 1.15 22918 17633 2 1110.678506 556.3453 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3479.8 - 817692 - - - 2.1717 - 1.983 0.246 - 177.3 1 2 0 0.0024 11 0 0 0 5.12E+08 4.47E+08 - - - 2.7092 0.9908 230117_WJC_METTL3_WT_vs_EV_F03.17636.17636.2 0.38 14-Oct K.ISALALLK[136.11].M sp|Q92905|CSN5_HUMAN 1 835.5622 1.43 22921 17636 2 835.567042 418.7884 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 8.75 3480.1 - 1.12E+06 - - - 5.747 - 2.188 0.167 - 194.9 1 2 0 0.0048 8 0 0 0 4.01E+07 2.80E+07 - - - 2.6344 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.17637.17637.2 0.0062 20-Sep K.VLVIGELGVGK.T sp|Q13637|RAB32_HUMAN 1 1082.6699 1.6 22922 17637 2 1082.670495 542.3422 Ras-related protein Rab-32 OS=Homo sapiens OX=9606 GN=RAB32 PE=1 SV=3 5.97 3480.2 - 570148 - - - 0.5071 - 1.911 0.361 - 133.1 1 2 0 0.0005 11 0 0 0 1.00E+07 6.26E+06 - - - 3.4592 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.17649.17649.2 0.0017 16-Sep R.LIDFLESGK.T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1020.5492 1.4 22929 17649 2 1020.551443 511.2819 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3481.6 - 1.75E+06 - - - 2.2351 - 1.669 0.369 - 176.5 1 2 0 0.0023 9 0 0 0 2.55E+08 1.82E+08 - - - 3.2476 0.9142 230117_WJC_METTL3_WT_vs_EV_F03.17650.17650.2 1.81 12-May K.GVIFYLR.D "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 9 866.5014 3.93 22930 17650 2 866.505074 434.258 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 8.75 3481.7 - 490314 - - - 4.2123 - 1.307 0.023 - 76.4 2 2 0 0.0037 7 0 0 0 1.23E+08 3.13E+07 - - - -0.0764 0.9562 230117_WJC_METTL3_WT_vs_EV_F03.17654.17654.2 6.14 12-Jun K.LFGELFK[136.11].L "sp|Q15032|R3HD1_HUMAN,tr|A0A804HIA8|A0A804HIA8_HUMAN,tr|H7C207|H7C207_HUMAN" 3 860.4887 0.09 22932 17654 2 860.489965 431.2516 R3H domain-containing protein 1 OS=Homo sapiens OX=9606 GN=R3HDM1 PE=1 SV=3 6 3482.2 - 1.59E+06 - - - 1.4224 - 1.147 0.002 - 87.5 1 2 0 0.0012 7 0 0 0 2.96E+07 3.26E+08 - - - -0.51 1 230117_WJC_METTL3_WT_vs_EV_F03.17655.17655.2 0.000347 14/22 K.LPVGTTATLYFR[166.11].D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1347.7426 1.23 22933 17655 2 1347.747218 674.8786 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3482.4 - 707930 - - - 3.4213 - 2.245 0.519 - 323.4 1 2 0 0.0046 12 0 0 0 2.96E+07 2.41E+07 - - - 5.0007 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.17656.17656.2 0.00229 14-Aug K.GFGFGLVK.L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 823.4592 1.21 22934 17656 2 823.459611 412.7369 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3482.4 - 9.51E+06 - - - 0.4688 - 1.493 0.431 - 214.7 1 2 0 0.0004 8 0 0 0 5.22E+08 4.32E+08 - - - 3.433 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17664.17664.2 0.0113 20-Nov K.EVFSMAGVVVR.A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1192.6274 1.24 22940 17664 2 1192.630113 597.321 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.1 3483.3 - 3.58E+06 - - - 2.2505 - 2.085 0.454 - 509.7 1 2 0 0.0027 11 0 0 0 3.34E+08 2.69E+08 - - - 4.3811 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.17665.17665.2 4.22E-05 20-Aug K.SEIEYYAMLAK.T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1316.6322 1.08 22941 17665 2 1316.631752 659.3234 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3483.4 - 340151 - - - -0.3706 - 1.907 0.485 - 116.1 1 2 0 -0.0005 11 0 0 0 1.78E+07 1.65E+07 - - - 4.3694 0.9942 230117_WJC_METTL3_WT_vs_EV_F03.17666.17666.2 0.00567 22-Sep R.LPVPESITGFAR.L "sp|Q8N5K1|CISD2_HUMAN,tr|I3L1N9|I3L1N9_HUMAN,tr|A0A2R8Y540|A0A2R8Y540_HUMAN" 3 1285.703 0.25 22942 17666 2 1285.707181 643.8588 CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1 6 3483.6 - 214511 - - - 3.2231 - 1.623 0.153 - 200 1 2 0 0.0041 12 0 0 0 5.84E+06 2.37E+07 - - - 1.444 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.17670.17670.2 0.000303 16-Sep K.FPTLWSGAR[166.11].S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1043.5428 1.35 22943 17670 2 1043.543287 522.7787 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 9.75 3484.1 - 1.72E+06 - - - 0.4811 - 1.87 0.404 - 309.9 1 2 0 0.0005 9 0 0 0 2.62E+08 1.94E+08 - - - 3.8357 0.9838 230117_WJC_METTL3_WT_vs_EV_F03.17672.17672.2 0.146 14-Jun K.TILSLMTR[166.11].E sp|P53396|ACLY_HUMAN 1 943.54 1.1 22945 17672 2 943.543088 472.7773 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.41 3484.3 - 2.90E+06 - - - 3.2643 - 1.333 0.103 - 111.8 1 2 0 0.0031 8 0 0 0 9.54E+07 8.67E+07 - - - 0.6677 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.17673.17673.2 0.0319 16-Sep R.YLGLLENVR[166.11].V "sp|O43795|MYO1B_HUMAN,sp|O94832|MYO1D_HUMAN,sp|Q9UBC5|MYO1A_HUMAN,sp|B0I1T2|MYO1G_HUMAN,tr|A0A3B3IU30|A0A3B3IU30_HUMAN,tr|G3V342|G3V342_HUMAN,tr|K7EIG7|K7EIG7_HUMAN,tr|E9PDF6|E9PDF6_HUMAN,tr|J3QRN6|J3QRN6_HUMAN" 9 1085.6109 2.13 22946 17673 2 1085.61331 543.8127 Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3 6 3484.4 - 681029 - - - 2.2522 - 1.845 0.184 - 273 1 2 0 0.0024 9 0 0 0 3.57E+07 1.68E+07 - - - 2.1712 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.17676.17676.2 0.000225 20-Nov K.SEIEYYAMLAK[136.11].T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1324.6464 1.08 22949 17676 2 1324.650874 663.3305 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3484.8 - 407571 - - - 3.3473 - 2.364 0.429 - 449.2 1 2 0 0.0044 11 0 0 0 1.78E+07 1.65E+07 - - - 4.5357 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.17680.17680.2 0.0499 16-Oct R.LAVLPYELR.F "sp|Q9ULX3|NOB1_HUMAN,tr|H3BUR4|H3BUR4_HUMAN" 2 1072.6281 1.17 22951 17680 2 1072.631671 537.3213 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 6 3485.3 - 1.51E+06 - - - 3.3469 - 2.105 0.199 - 516.1 1 2 0 0.0036 9 0 0 0 2.20E+08 1.88E+08 - - - 2.663 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.17681.17681.2 0.00354 18-Oct R.LSALLALASK.V "sp|Q96A35|RM24_HUMAN,tr|X6RHI2|X6RHI2_HUMAN,tr|X6RJ73|X6RJ73_HUMAN,tr|X6RIR5|X6RIR5_HUMAN" 4 985.6172 1.64 22952 17681 2 985.620554 493.8159 "39S ribosomal protein L24, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL24 PE=1 SV=1" 8.75 3485.4 - 1.10E+06 - - - 3.4212 - 2.098 0.429 - 217.8 1 2 0 0.0034 10 0 0 0 2.69E+07 1.64E+07 - - - 4.2768 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.17687.17687.2 0.0152 16-Jul K.VNIIPIIAK.A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 979.643 1.07 22956 17687 2 979.64577 490.8288 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3486.1 - 681509 - - - 2.8245 - 1.378 0.325 - 137.4 1 2 0 0.0028 9 0 0 0 8.43E+07 7.85E+07 - - - 2.3682 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.17692.17692.2 0.484 16-Oct K.IAFAITAIK[136.11].G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 954.5994 1.19 22960 17692 2 954.601677 478.307 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3486.7 - 1.54E+06 - - - 2.4335 - 1.901 0.219 - 177.5 1 2 0 0.0023 9 0 0 0 1.44E+10 1.21E+10 - - - 2.5162 0.998 230117_WJC_METTL3_WT_vs_EV_F03.17694.17694.2 2.04 14-Aug K.IYQVLDFR.L "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1052.5655 1.52 22961 17694 2 1052.568585 527.29 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 5.84 3486.9 - 2.56E+06 - - - 2.949 - 1.75 0.207 - 239.5 1 2 0 0.0031 8 0 0 0 6.34E+07 4.16E+07 - - - 2.2567 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.17695.17695.2 0.0266 16-Jul R.AVDVGAFLR[166.11].D "sp|Q96BT3|CENPT_HUMAN,tr|H3BUW2|H3BUW2_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 3 956.5319 1 22962 17695 2 956.533775 479.2732 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 5.88 3487 - 1.38E+06 - - - 1.9748 - 1.64 0.26 - 138.3 1 2 0 0.0019 9 0 0 0 5.24E+07 5.24E+07 - - - 2.3919 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.17697.17697.2 0.0706 14-Sep K.IYQVLDFR[166.11].L "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1062.5738 1.86 22964 17697 2 1062.576973 532.2942 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 5.84 3487.1 - 1.09E+06 - - - 3.0323 - 1.864 0.281 - 315.4 1 2 0 0.0032 8 0 0 0 8.36E+07 4.49E+07 - - - 2.9936 0.9967 230117_WJC_METTL3_WT_vs_EV_F03.17705.17705.2 0.16 14-Jul K.TILSLMTR.E sp|P53396|ACLY_HUMAN 1 933.5317 1.05 22970 17705 2 933.534235 467.7731 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.41 3488.1 - 2.63E+06 - - - 2.6748 - 1.214 0.274 - 160.9 1 2 0 0.0025 8 0 0 0 9.78E+07 9.32E+07 - - - 1.6488 0.9869 230117_WJC_METTL3_WT_vs_EV_F03.17711.17711.2 1.68 14-Jul R.DILIDPIR[166.11].V "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 963.5629 1.67 22973 17711 2 963.563151 482.7887 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3488.9 - 242048 - - - 0.3103 - 1.214 0.111 - 104.2 1 2 0 0.0003 8 0 0 0 5.66E+07 3.40E+07 - - - 0.4456 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.17719.17719.2 0.111 14-Aug R.GIFPVLC[160.03]K[136.11].D "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 940.5296 1.93 22976 17719 2 940.533549 471.2721 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 8.22 3489.9 - 1.13E+06 - - - 4.2412 - 1.673 0.26 - 201.9 1 2 0 0.004 8 0 0 0 1.01E+08 5.23E+07 - - - 2.5122 0.9958 230117_WJC_METTL3_WT_vs_EV_F03.17730.17730.2 2.33 12-Jul R.ISPWLLR[166.11].V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 893.5362 0.84 22983 17730 2 893.537959 447.7754 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3491.4 - 1.37E+06 - - - 1.9205 - 1.413 0.141 - 171.3 1 2 0 0.0017 7 0 0 0 2.65E+07 3.16E+07 - - - 1.1773 0.9589 230117_WJC_METTL3_WT_vs_EV_F03.17731.17731.2 0.000196 14-Sep S.PLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 906.5526 1.27 22984 17731 2 906.553692 454.2836 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 10.18 3491.5 - 1.05E+06 - - - 1.1814 - 1.935 0.283 - 333 1 1 0 0.0011 8 0 0 0 1.43E+08 1.13E+08 - - - 3.1218 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.17734.17734.2 0.0552 20-Oct R.YIVQVSPLGIR.L sp|Q10570|CPSF1_HUMAN 1 1243.7289 1.38 22987 17734 2 1243.732604 622.8717 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3491.8 - 542554 - - - 3.0119 - 1.69 0.272 - 293.6 1 2 0 0.0037 11 0 0 0 4.22E+07 3.06E+07 - - - 2.4683 0.9929 230117_WJC_METTL3_WT_vs_EV_F03.17740.17740.2 0.0863 12-Jul R.ISPWLLR.V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 883.528 0.3 22991 17740 2 883.530661 442.7713 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3492.5 - 1.59E+06 - - - 3.0423 - 1.406 0.144 - 132.7 1 2 0 0.0027 7 0 0 0 6.91E+07 2.27E+08 - - - 1.1834 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.17742.17742.2 0.000185 16-Sep K.FPTLWSGAR.S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1033.5345 0.91 22993 17742 2 1033.537575 517.7745 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 9.75 3492.6 - 3.63E+06 - - - 2.9607 - 1.931 0.315 - 331.5 1 2 0 0.0031 9 0 0 0 1.55E+08 1.70E+08 - - - 3.2704 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.17748.17748.2 0.204 14-Jul R.DILIDPIR.V "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 953.5546 1.65 22997 17748 2 953.556496 477.7846 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3493.4 - 1.52E+06 - - - 2.0072 - 1.498 0.288 - 185.2 1 2 0 0.0019 8 0 0 0 5.59E+07 3.38E+07 - - - 2.3864 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.17751.17751.2 0.000179 28-Sep R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 12.44 23000 17751 2 1494.913409 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3493.7 - 259674 - - - -1.8369 - 1.895 0.476 - 190.7 1 2 0 -0.0027 15 0 0 0 2.39E+07 1.92E+06 - - - 4.1274 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.17755.17755.2 0.00231 16-Aug R.FLVQLDDYR.F "sp|Q9HAD4|WDR41_HUMAN,tr|D6RE66|D6RE66_HUMAN,tr|B4DK73|B4DK73_HUMAN,tr|D6RH33|D6RH33_HUMAN,tr|D6RA22|D6RA22_HUMAN,tr|B4DHS8|B4DHS8_HUMAN,tr|D6R9E7|D6R9E7_HUMAN,tr|H0YAA3|H0YAA3_HUMAN,tr|D6RBY6|D6RBY6_HUMAN,tr|H0YAI6|H0YAI6_HUMAN,tr|D6RB94|D6RB94_HUMAN" 11 1167.5924 1.59 23002 17755 2 1167.59188 584.8035 WD repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=WDR41 PE=1 SV=3 4.21 3494.2 - 369610 - - - -0.4659 - 1.589 0.295 - 241.8 1 2 0 -0.0005 9 0 0 0 2.04E+07 1.28E+07 - - - 2.5595 0.999 230117_WJC_METTL3_WT_vs_EV_F03.17756.17756.2 0.00333 14-Aug K.WLTLEVC[160.03]R.E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1075.5485 1.74 23003 17756 2 1075.551701 538.7815 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3494.3 - 6.20E+06 - - - 3.0217 - 1.793 0.323 - 292.1 1 2 0 0.0032 8 0 0 0 2.22E+08 1.28E+08 - - - 3.1866 1 230117_WJC_METTL3_WT_vs_EV_F03.17757.17757.2 1.38E-07 22-Nov R.VFIGNLNTALVK[136.11].K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1295.7693 0.39 23004 17757 2 1295.771853 648.8919 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3494.4 - 510226 - - - 1.9911 - 2.324 0.55 - 313.8 1 2 0 0.0026 12 0 0 0 8.01E+07 2.05E+08 - - - 5.3213 1 230117_WJC_METTL3_WT_vs_EV_F03.17761.17761.2 2.69E-05 20-Nov R.IVLLDSSLEYK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1278.7071 10.28 23006 17761 2 1278.709421 640.3608 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3494.9 - 1.38E+06 - - - 1.8003 - 2.393 0.503 - 369.5 1 2 0 0.0023 11 0 0 0 6.47E+09 6.29E+08 - - - 5.1159 0.9799 230117_WJC_METTL3_WT_vs_EV_F03.17764.17764.2 0.0946 Jun-32 R.ASSGGGAGGAAGYAPVK.Y sp|P25067|CO8A2_HUMAN 1 1376.6684 2.65 23009 17764 2 1376.666086 689.3415 Collagen alpha-2(VIII) chain OS=Homo sapiens OX=9606 GN=COL8A2 PE=1 SV=2 8.63 3495.2 - 645867 - - - -1.7114 - 1.314 0.176 - 52.3 1 2 0 -0.0024 17 0 0 0 5.67E+07 2.14E+07 - - - 1.0116 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.17765.17765.2 0.00124 16-Aug R.FLVQLDDYR[166.11].F "sp|Q9HAD4|WDR41_HUMAN,tr|D6RE66|D6RE66_HUMAN,tr|B4DK73|B4DK73_HUMAN,tr|D6RH33|D6RH33_HUMAN,tr|D6RA22|D6RA22_HUMAN,tr|B4DHS8|B4DHS8_HUMAN,tr|D6R9E7|D6R9E7_HUMAN,tr|H0YAA3|H0YAA3_HUMAN,tr|D6RBY6|D6RBY6_HUMAN,tr|H0YAI6|H0YAI6_HUMAN,tr|D6RB94|D6RB94_HUMAN" 11 1177.6007 1.59 23010 17765 2 1177.605314 589.8076 WD repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=WDR41 PE=1 SV=3 4.21 3495.3 - 448364 - - - 3.9232 - 1.678 0.421 - 225 1 2 0 0.0046 9 0 0 0 2.04E+07 1.28E+07 - - - 3.6465 0.8834 230117_WJC_METTL3_WT_vs_EV_F03.17766.17766.2 7.57 12-Jul K.LFLDSLR[166.11].K "sp|P21359|NF1_HUMAN,sp|Q8N456|LRC18_HUMAN,sp|Q96EK5|KBP_HUMAN,tr|A0A6Q8PHL8|A0A6Q8PHL8_HUMAN,tr|J3KSB5|J3KSB5_HUMAN,tr|A0A6Q8PGG2|A0A6Q8PGG2_HUMAN,tr|A0A1B0GUA3|A0A1B0GUA3_HUMAN,tr|A0A6Q8PH45|A0A6Q8PH45_HUMAN" 8 872.4995 1.44 23011 17766 2 872.497332 437.257 Neurofibromin OS=Homo sapiens OX=9606 GN=NF1 PE=1 SV=2 5.84 3495.4 - 407220 - - - -2.5112 - 1.196 0.062 - 108.1 1 2 0 -0.0022 7 0 0 0 1.63E+07 1.13E+07 - - - 0.0654 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.17770.17770.2 0.00208 14-Sep K.WLTLEVC[160.03]R[166.11].E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1085.5567 1.74 23013 17770 2 1085.560279 543.7856 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3495.9 - 4.74E+06 - - - 3.2776 - 1.99 0.401 - 456.7 1 2 0 0.0036 8 0 0 0 2.25E+08 1.29E+08 - - - 4.0771 1 230117_WJC_METTL3_WT_vs_EV_F03.17771.17771.2 4.71E-06 22-Oct R.VFIGNLNTALVK.K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1287.7551 0.39 23014 17771 2 1287.764104 644.8848 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3496 - 2.11E+06 - - - 7.013 - 2.128 0.552 - 288.3 1 2 0 0.009 12 0 0 0 8.01E+07 2.04E+08 - - - 5.1022 0.9897 230117_WJC_METTL3_WT_vs_EV_F03.17774.17774.2 1.17 12-Jun R.YLNFFTK[136.11].A sp|P12004|PCNA_HUMAN 1 939.4946 1.39 23017 17774 2 939.49592 470.7546 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3496.3 - 827373 - - - 1.454 - 1.073 0.161 - 102.8 1 2 0 0.0014 7 0 0 0 1.59E+08 1.14E+08 - - - 0.453 0.9919 230117_WJC_METTL3_WT_vs_EV_F03.17776.17776.2 0.0174 14-Jun R.AFFSSYLK[136.11].S "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 969.5051 0.86 23019 17776 2 969.508668 485.7598 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.63 3496.5 - 504727 - - - 3.6606 - 1.133 0.268 - 89 1 2 0 0.0035 8 0 0 0 5.61E+07 6.52E+07 - - - 1.3959 1 230117_WJC_METTL3_WT_vs_EV_F03.17779.17779.2 8.99E-05 18-Dec K.IIQLLDDYPK.C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1216.6703 1.02 23022 17779 2 1216.667197 609.3424 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3496.9 - 343140 - - - -2.5833 - 2.248 0.501 - 414.1 1 2 0 -0.0031 10 0 0 0 8.81E+08 8.60E+08 - - - 5.0015 1 230117_WJC_METTL3_WT_vs_EV_F03.17784.17784.2 0.000123 20-Dec K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 11.74 23025 17784 2 1204.683948 603.3481 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3497.6 - 1.53E+07 - - - 1.9715 - 2.506 0.542 - 623.2 1 2 0 0.0024 11 0 0 0 5.98E+09 5.09E+08 - - - 5.5287 1 230117_WJC_METTL3_WT_vs_EV_F03.17785.17785.2 2.82E-06 20-Dec K.FATEAAITILR[166.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1214.6898 11.74 23026 17785 2 1214.69363 608.3522 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3497.7 - 1.69E+06 - - - 3.1177 - 2.398 0.561 - 596.6 1 2 0 0.0038 11 0 0 0 5.97E+09 5.09E+08 - - - 5.5495 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.17786.17786.2 0.0809 18-Aug K.IIQLLDDYPK[136.11].C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1224.6845 1.02 23027 17786 2 1224.683387 613.3495 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3497.8 - 1.97E+06 - - - -0.9415 - 2.06 0.433 - 141.9 1 2 0 -0.0012 10 0 0 0 8.81E+08 8.60E+08 - - - 4.2561 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.17787.17787.2 0.0689 12-Jul R.YLNFFTK.A sp|P12004|PCNA_HUMAN 1 931.4804 1.39 23028 17787 2 931.483033 466.7475 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3497.8 - 1.58E+06 - - - 2.8761 - 1.372 0.318 - 120.6 1 2 0 0.0027 7 0 0 0 1.59E+08 1.14E+08 - - - 2.391 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.17788.17788.2 1.2 14-Oct R.IVEVLLIK.D "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 925.6212 1.14 23029 17788 2 925.622658 463.8179 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6 3497.9 - 1.30E+06 - - - 1.5698 - 1.919 0.361 - 221 1 2 0 0.0015 8 0 0 0 6.49E+07 5.69E+07 - - - 3.6727 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.17790.17790.2 5.84E-05 18-Sep R.LMDEAVLALR.N sp|Q92616|GCN1_HUMAN 1 1129.6165 0.78 23031 17790 2 1129.62028 565.8155 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3498.1 - 909059 - - - 3.3197 - 1.963 0.442 - 233.2 1 2 0 0.0037 10 0 0 0 2.83E+07 3.62E+07 - - - 4.1871 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.17795.17795.2 0.015 14-Aug K.NVFNALIR.L "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 945.5396 1.23 23034 17795 2 945.54183 473.7771 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 9.75 3498.7 - 2.07E+06 - - - 2.3584 - 1.637 0.149 - 245.3 1 2 0 0.0022 8 0 0 0 1.17E+08 9.50E+07 - - - 1.6273 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.17796.17796.2 0.0397 14-Jul R.AFFSSYLK.S "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 961.4909 0.86 23035 17796 2 961.492363 481.7527 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.63 3498.8 - 1.60E+06 - - - 1.5018 - 1.286 0.332 - 140.5 1 2 0 0.0014 8 0 0 0 5.61E+07 6.52E+07 - - - 2.2513 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.17798.17798.3 0.0265 Dec-40 K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 9.03 23037 17798 3 1204.683651 402.5678 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3498.9 - 1.60E+06 - - - 1.7249 - 2.072 0.35 - 144.2 1 2 0 0.0021 11 0 0 0 2.12E+08 2.34E+07 - - - 4.5112 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.17803.17803.2 0.00321 16-Oct K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 0.85 23040 17803 2 993.586384 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 3499.6 - 1.80E+06 - - - 1.7452 - 2.168 0.311 - 441.4 1 2 0 0.0017 9 0 0 0 6.73E+07 7.95E+07 - - - 3.5762 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.17804.17804.2 0.00696 20-Nov K.VLLQSALSLGR.S "sp|Q96T51|RUFY1_HUMAN,tr|H0Y9Y8|H0Y9Y8_HUMAN,tr|J3KPP6|J3KPP6_HUMAN" 3 1155.6976 1.75 23041 17804 2 1155.702808 578.8561 RUN and FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RUFY1 PE=1 SV=2 9.72 3499.7 - 644279 - - - 4.5427 - 2.087 0.397 - 343.8 1 2 0 0.0053 11 0 0 0 1.01E+07 5.80E+06 - - - 3.9619 0.9814 230117_WJC_METTL3_WT_vs_EV_F03.17805.17805.2 0.323 12-Jul R.WLITLNK.Q "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 886.5276 1.09 23042 17805 2 886.528516 444.2711 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 8.75 3499.7 - 2.83E+06 - - - 0.9893 - 1.262 0.039 - 133.5 1 2 0 0.0009 7 0 0 0 4.59E+08 4.22E+08 - - - 0.0661 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.17818.17818.2 0.0052 18-Nov R.LMDEAVLALR[166.11].N sp|Q92616|GCN1_HUMAN 1 1139.6248 0.78 23051 17818 2 1139.62958 570.8197 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3501.4 - 1.31E+06 - - - 4.1944 - 1.998 0.352 - 396.9 1 2 0 0.0048 10 0 0 0 2.84E+07 3.64E+07 - - - 3.5714 1 230117_WJC_METTL3_WT_vs_EV_F03.17821.17821.2 1.21E-05 20-Dec R.VAMYVHAYTLY.S "sp|P25788|PSA3_HUMAN,tr|H0YJ03|H0YJ03_HUMAN,tr|G3V4X5|G3V4X5_HUMAN" 3 1329.6427 - 23052 17821 2 1329.642282 665.8286 Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2 6.71 3501.8 - 1.03E+06 - - - -0.3482 - 2.073 0.514 - 513.2 1 1 0 -0.0005 11 0 0 0 - - - - - 4.8094 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17826.17826.2 0.00953 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 999 23055 17826 2 1006.570799 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3502.4 - 4.54E+07 - - - 0.8951 - 1.939 0.473 - 253.6 1 2 0 0.0009 9 0 0 0 1.67E+09 0.00E+00 - - - 4.45 0.9485 230117_WJC_METTL3_WT_vs_EV_F03.17827.17827.3 0.161 Aug-40 K.FATEAAITILR[166.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1214.6898 9.01 23056 17827 3 1214.690205 405.9039 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3502.5 - 930303 - - - 0.298 - 1.596 0.075 - 58.2 2 2 0 0.0004 11 0 0 0 2.11E+08 2.34E+07 - - - 0.5648 0.998 230117_WJC_METTL3_WT_vs_EV_F03.17833.17833.2 0.454 16-Jul K.AAIDWFDGK.E "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1021.4869 1.15 23058 17833 2 1021.490216 511.7507 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.21 3503.3 - 428864 - - - 3.2502 - 1.466 0.315 - 102.1 1 2 0 0.0033 9 0 0 0 1.27E+07 1.11E+07 - - - 2.4732 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.17834.17834.2 0.0668 18-Aug R.FGFGFGNGMK[136.11].Q "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 8 1068.4942 0.83 23059 17834 2 1068.495737 535.2544 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 8.75 3503.4 - 1.56E+06 - - - 1.4038 - 1.25 0.25 - 72.4 1 2 0 0.0015 10 0 0 0 1.63E+07 1.97E+07 - - - 1.5099 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.17835.17835.2 0.000978 16-Sep K.AENPYLFLR.G "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN" 2 1121.5869 1.36 23060 17835 2 1121.586048 561.8007 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 6.05 3503.5 - 1.04E+06 - - - -0.7998 - 1.501 0.347 - 261.6 1 2 0 -0.0009 9 0 0 0 2.12E+07 1.55E+07 - - - 2.7786 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.17839.17839.2 0.142 18-Sep K.SFIMSSTLIR[166.11].H sp|Q9UEG4|ZN629_HUMAN 1 1163.6248 1.3 23062 17839 2 1163.629874 582.8197 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.47 3504 - 481388 - - - 4.3605 - 1.749 0.314 - 239.1 1 2 0 0.0051 10 0 0 0 1.69E+07 1.29E+07 - - - 2.9191 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.17841.17841.2 0.369 18-Aug K.LADQIFAYYK[136.11].V "sp|Q7L576|CYFP1_HUMAN,sp|Q96F07|CYFP2_HUMAN,tr|A0A0G2JR96|A0A0G2JR96_HUMAN,tr|E7EW33|E7EW33_HUMAN,tr|H7C229|H7C229_HUMAN,tr|E7EVJ5|E7EVJ5_HUMAN,tr|A0A0G2JQT1|A0A0G2JQT1_HUMAN" 7 1238.6427 0.88 23063 17841 2 1238.64382 620.3286 Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens OX=9606 GN=CYFIP1 PE=1 SV=1 5.83 3504.2 - 392996 - - - 0.9244 - 1.678 0.134 - 116.2 1 2 0 0.0011 10 0 0 0 5.51E+06 6.29E+06 - - - 1.4752 1 230117_WJC_METTL3_WT_vs_EV_F03.17844.17844.2 5.12E-07 18-Dec R.EC[160.03]LNLWGYER.V sp|Q86U44|MTA70_HUMAN 1 1338.6027 25.23 23066 17844 2 1338.60709 670.3086 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3504.6 - 1.21E+06 - - - 3.3012 - 2.207 0.563 - 797.3 1 2 0 0.0044 10 0 0 0 1.19E+08 4.73E+06 - - - 5.4076 0.9956 230117_WJC_METTL3_WT_vs_EV_F03.17845.17845.2 0.273 18-Aug K.SFIMSSTLIR.H sp|Q9UEG4|ZN629_HUMAN 1 1153.6165 1.3 23067 17845 2 1153.617526 577.8155 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.47 3504.7 - 657699 - - - 0.8634 - 1.137 0.231 - 146.9 1 2 0 0.001 10 0 0 0 1.69E+07 1.29E+07 - - - 1.1052 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.17848.17848.2 0.0677 12-Jul R.LILMDLK.G "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 844.5092 2.69 23068 17848 2 844.510223 423.2619 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.84 3505.1 - 1.40E+06 - - - 1.1971 - 1.61 0.181 - 145.3 1 2 0 0.001 7 0 0 0 5.59E+07 2.08E+07 - - - 1.8865 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.17850.17850.2 0.0411 20-Nov R.YGLIGLNGIGK[136.11].S "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1111.6481 2.27 23070 17850 2 1111.645418 556.8313 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.59 3505.3 - 1.23E+06 - - - -2.4081 - 1.935 0.33 - 232.5 1 2 0 -0.0027 11 0 0 0 6.95E+07 3.06E+07 - - - 3.2633 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.17851.17851.2 0.00176 16-Aug K.NFDMVIVYK[136.11].D sp|Q9Y5B9|SP16H_HUMAN 1 1135.5827 1.05 23071 17851 2 1135.580969 568.7986 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.83 3505.5 - 839652 - - - -1.5393 - 1.488 0.349 - 130.2 1 2 0 -0.0017 9 0 0 0 1.95E+07 1.86E+07 - - - 2.768 0.9907 230117_WJC_METTL3_WT_vs_EV_F03.17853.17853.2 0.256 14-Jul R.FLLETVVR.V "sp|Q5R372|RBG1L_HUMAN,tr|A0A0U1RRM5|A0A0U1RRM5_HUMAN,tr|A0A0C4DG54|A0A0C4DG54_HUMAN,tr|A0A804HKD7|A0A804HKD7_HUMAN" 4 975.5753 0.57 23073 17853 2 975.577486 488.7949 Rab GTPase-activating protein 1-like OS=Homo sapiens OX=9606 GN=RABGAP1L PE=1 SV=1 6 3505.7 - 300959 - - - 2.2233 - 1.271 0.121 - 126.1 1 2 0 0.0022 8 0 0 0 5.91E+06 1.04E+07 - - - 0.6573 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.17857.17857.2 0.00837 14-Aug R.NILIVLTK[136.11].L "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN,tr|H0Y815|H0Y815_HUMAN" 3 920.615 0.88 23075 17857 2 920.615959 461.3148 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 8.75 3506.1 - 1.49E+06 - - - 1.0374 - 1.381 0.357 - 167 1 2 0 0.001 8 0 0 0 1.90E+07 2.15E+07 - - - 2.6511 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.17858.17858.2 0.000177 16-Oct K.NFDMVIVYK.D sp|Q9Y5B9|SP16H_HUMAN 1 1127.5685 1.04 23076 17858 2 1127.57438 564.7915 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.83 3506.2 - 1.06E+06 - - - 5.1997 - 1.747 0.516 - 304.5 1 2 0 0.0059 9 0 0 0 1.93E+07 1.86E+07 - - - 4.4644 0.9894 230117_WJC_METTL3_WT_vs_EV_F03.17861.17861.3 0.0706 Jul-40 R.IVLLDSSLEYK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1278.7071 18.52 23079 17861 3 1278.712956 427.243 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3506.5 - 685378 - - - 4.5648 - 1.656 0.257 - 71.6 4 2 0 0.0058 11 0 0 0 2.65E+07 1.43E+06 - - - 2.558 0.9645 230117_WJC_METTL3_WT_vs_EV_F03.17865.17865.2 8.05 14-Jul R.TLIEELPS.- sp|Q9UHR6|ZNHI2_HUMAN 1 900.4804 - 23082 17865 2 900.479028 451.2475 Zinc finger HIT domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZNHIT2 PE=1 SV=1 3.79 3507 - 889739 - - - -1.5392 - 1.11 0.156 - 135 1 2 0 -0.0014 8 0 0 0 - - - - - 0.5075 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.17867.17867.2 0.0426 18-Sep R.FLLADNLYC[160.03]K.A sp|P61758|PFD3_HUMAN 1 1255.6271 3.85 23083 17867 2 1255.629454 628.8208 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 5.83 3507.2 - 2.57E+06 - - - 1.8787 - 1.865 0.35 - 183.7 1 2 0 0.0024 10 0 0 0 6.64E+07 1.72E+07 - - - 3.3651 0.9956 230117_WJC_METTL3_WT_vs_EV_F03.17869.17869.2 1.02 14-Aug R.NILIVLTK.L "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN,tr|H0Y815|H0Y815_HUMAN" 3 912.6008 0.88 23085 17869 2 912.602902 457.3077 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 8.75 3507.4 - 1.26E+06 - - - 2.2989 - 1.489 0.137 - 201.3 1 2 0 0.0021 8 0 0 0 1.90E+07 2.15E+07 - - - 1.2529 0.9894 230117_WJC_METTL3_WT_vs_EV_F03.17871.17871.2 0.349 14-Aug K.IDLNLLTR[166.11].L sp|Q9UHB7|AFF4_HUMAN 1 966.5738 0.18 23087 17871 2 966.573514 484.2942 AF4\FMR2 family member 4 OS=Homo sapiens OX=9606 GN=AFF4 PE=1 SV=1 5.84 3507.7 - 576923 - - - -0.2452 - 1.371 0.11 - 102.6 1 2 0 -0.0002 8 0 0 0 3.25E+06 1.79E+07 - - - 0.805 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.17872.17872.2 0.0212 14-Sep R.LSVLLGLK.K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 841.5637 2.28 23088 17872 2 841.565594 421.7891 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3507.8 - 535286 - - - 2.2625 - 1.963 0.333 - 206 1 2 0 0.0019 8 0 0 0 1.11E+07 4.86E+06 - - - 3.5341 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.17873.17873.2 0.000412 14-Sep R.LSVLLGLK[136.11].K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 849.5779 2.28 23089 17873 2 849.578804 425.7962 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3507.9 - 425909 - - - 1.0758 - 1.879 0.248 - 172.3 1 2 0 0.0009 8 0 0 0 1.11E+07 4.86E+06 - - - 2.7747 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.17874.17874.2 4.94E-06 20-Dec K.LALDMEINAYR.K sp|Q03252|LMNB2_HUMAN 1 1307.6544 0.67 23090 17874 2 1307.654766 654.8345 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.37 3508.1 - 285528 - - - 0.3013 - 2.401 0.319 - 714.4 1 2 0 0.0004 11 0 0 0 2.97E+06 4.42E+06 - - - 3.7665 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.17878.17878.2 0.0606 14-Aug R.LDTIFFAK.Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 953.5222 2.57 23093 17878 2 953.524683 477.7684 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3508.4 - 1.38E+06 - - - 2.5841 - 1.78 0.139 - 153.1 1 2 0 0.0025 8 0 0 0 2.94E+08 1.14E+08 - - - 1.8059 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.17879.17879.2 0.0248 14-Aug R.LDTIFFAK[136.11].Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 961.5364 2.57 23094 17879 2 961.539409 481.7755 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3508.5 - 862065 - - - 3.1096 - 1.708 0.198 - 154.6 1 2 0 0.003 8 0 0 0 2.84E+08 1.11E+08 - - - 2.117 1 230117_WJC_METTL3_WT_vs_EV_F03.17883.17883.2 0.000176 18-Sep K.VEDAMLMFDK.T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|A0A6Q8PHP1|A0A6Q8PHP1_HUMAN" 6 1197.541 2.72 23096 17883 2 1197.54412 599.7778 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.03 3509.1 - 1.62E+06 - - - 2.6204 - 2.041 0.523 - 288.7 1 2 0 0.0031 10 0 0 0 2.29E+07 8.42E+06 - - - 4.8943 0.9917 230117_WJC_METTL3_WT_vs_EV_F03.17887.17887.2 0.0175 20-Jul K.LPVVISQC[160.03]GEM.- "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1231.5941 - 23100 17887 2 1231.59876 616.8043 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4 3509.4 - 987249 - - - 3.8 - 1.126 0.283 - 107.4 1 2 0 0.0047 11 0 0 0 - - - - - 1.4508 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.17888.17888.2 1.59E-05 18-Dec K.VDDAMLMFDK[136.11].T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1191.5395 1.35 23101 17888 2 1191.539991 596.777 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 3.93 3509.5 - 947615 - - - 0.3852 - 2.715 0.335 - 633.7 1 2 0 0.0005 10 0 0 0 6.43E+07 4.76E+07 - - - 4.3031 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.17889.17889.2 0.274 14-May R.VLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 815.4753 0.23 23102 17889 2 815.476843 408.7449 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 3509.6 - 353001 - - - 1.9302 - 0.998 0.319 - 69.2 1 2 0 0.0016 8 0 0 0 1.02E+07 4.55E+07 - - - 1.3906 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.17890.17890.2 0.124 24-Nov R.LPLLPPESPGPLR.Q "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN,tr|A0A669KAX5|A0A669KAX5_HUMAN" 6 1384.8078 5.8 23103 17890 2 1384.811911 693.4112 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 6 3509.8 - 310085 - - - 2.9426 - 2.191 0.301 - 343.8 1 2 0 0.0041 13 0 0 0 2.06E+06 3.55E+05 - - - 3.276 1 230117_WJC_METTL3_WT_vs_EV_F03.17896.17896.2 1.01E-07 18-Dec K.VDDAMLMFDK.T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1183.5253 1.35 23107 17896 2 1183.529983 592.7699 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 3.93 3510.5 - 1.93E+06 - - - 3.9298 - 2.37 0.651 - 542.1 1 2 0 0.0047 10 0 0 0 6.44E+07 4.77E+07 - - - 6.2564 0.9941 230117_WJC_METTL3_WT_vs_EV_F03.17900.17900.2 0.103 14-Jul R.ADLIAYLK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 905.5222 1.39 23111 17900 2 905.524793 453.7684 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 5.88 3510.8 - 785143 - - - 2.8426 - 1.35 0.175 - 119.8 1 2 0 0.0026 8 0 0 0 3.69E+07 2.66E+07 - - - 1.2378 0.9464 230117_WJC_METTL3_WT_vs_EV_F03.17901.17901.2 0.0011 20-Aug R.LVHPGVAEVVF.V "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1165.6495 - 23112 17901 2 1165.653132 583.832 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.24 3510.9 - 774876 - - - 3.0773 - 1.752 0.425 - 205.2 1 1 0 0.0036 11 0 0 0 - - - - - 3.6959 1 230117_WJC_METTL3_WT_vs_EV_F03.17906.17906.2 4.18E-07 30-Dec K.VLAQNSGFDLQETLVK.L sp|P40227|TCPZ_HUMAN 1 1760.9309 58.38 23117 17906 2 1760.935447 881.4727 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3511.5 - 268957 - - - 2.602 - 2.623 0.596 - 408.6 1 2 0 0.0046 16 0 0 0 2.72E+06 4.66E+04 - - - 5.8124 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.17910.17910.2 0.00333 14-Sep K.NILTEIYR.L sp|Q15907|RB11B_HUMAN 1 1020.5604 1.59 23119 17910 2 1020.56396 511.2875 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 6 3512 - 2.86E+06 - - - 3.4932 - 1.807 0.394 - 298.1 1 2 0 0.0036 8 0 0 0 5.07E+07 3.20E+07 - - - 3.7344 1 230117_WJC_METTL3_WT_vs_EV_F03.17911.17911.2 3.97E-06 13/24 K.VLATTFDPYLGGR.N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1408.7351 12.18 23120 17911 2 1408.739953 705.3748 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3512.1 - 2.43E+06 - - - 3.4698 - 3.067 0.575 - 393.5 1 2 0 0.0049 13 0 0 0 9.19E+07 7.55E+06 - - - 6.1627 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.17912.17912.2 0.00883 16-Sep R.FLSPEFIPR[166.11].R "sp|P49406|RM19_HUMAN,tr|A0A0A0MRF4|A0A0A0MRF4_HUMAN" 2 1114.6051 0.87 23121 17912 2 1114.610119 558.3098 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 6 3512.1 - 1.99E+06 - - - 4.5469 - 1.675 0.324 - 247.1 1 2 0 0.0051 9 0 0 0 5.35E+07 6.12E+07 - - - 2.9247 0.999 230117_WJC_METTL3_WT_vs_EV_F03.17913.17913.2 0.0699 16-Sep R.FLSPEFIPR.R "sp|P49406|RM19_HUMAN,tr|A0A0A0MRF4|A0A0A0MRF4_HUMAN" 2 1104.5968 0.87 23122 17913 2 1104.600394 553.3057 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 6 3512.2 - 2.25E+06 - - - 3.2709 - 1.695 0.376 - 195.5 1 2 0 0.0036 9 0 0 0 5.18E+07 5.97E+07 - - - 3.3436 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.17916.17916.2 0.0145 14/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 11.56 23125 17916 2 1484.914785 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3512.5 - 427250 - - - 4.6468 - 2.079 0.383 - 430.9 1 2 0 0.0069 15 0 0 0 4.02E+07 3.48E+06 - - - 3.667 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.17917.17917.2 0.0629 20-Sep R.ELLIIGGVAAR[166.11].D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1120.6844 1.15 23126 17917 2 1120.688304 561.3495 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3512.6 - 404172 - - - 3.5157 - 1.74 0.292 - 170.9 1 2 0 0.0039 11 0 0 0 4.97E+08 4.31E+08 - - - 2.6949 1 230117_WJC_METTL3_WT_vs_EV_F03.17921.17921.2 5.43E-08 14/24 K.VLATTFDPYLGGR[166.11].N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1418.7433 12.15 23130 17921 2 1418.750878 710.3789 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3513.1 - 301053 - - - 5.3167 - 2.892 0.56 - 555.1 1 2 0 0.0075 13 0 0 0 9.17E+07 7.55E+06 - - - 5.9003 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.17923.17923.2 0.071 20-Aug R.C[160.03]LAPMMSEVIR.L "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 1305.6243 1.67 23132 17923 2 1305.627343 653.8194 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 5.99 3513.4 - 245078 - - - 2.3039 - 1.579 0.336 - 172.1 1 2 0 0.003 11 0 0 0 2.80E+06 1.68E+06 - - - 2.7575 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.17926.17926.2 0.0293 20-Aug K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 3.19 23135 17926 2 1235.765406 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3513.8 - 207686 - - - 4.2468 - 1.731 0.359 - 131.7 1 2 0 0.0052 11 0 0 0 3.60E+06 1.13E+06 - - - 3.1753 0.9925 230117_WJC_METTL3_WT_vs_EV_F03.17928.17928.2 0.229 14-Aug K.LILTPFER.N "sp|Q9H089|LSG1_HUMAN,tr|F8WFC6|F8WFC6_HUMAN" 2 987.5753 1.12 23136 17928 2 987.579282 494.7949 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 6 3514 - 1.61E+06 - - - 4.0149 - 1.535 0.18 - 183 1 2 0 0.004 8 0 0 0 7.21E+07 6.47E+07 - - - 1.6617 0.9915 230117_WJC_METTL3_WT_vs_EV_F03.17932.17932.2 0.98 14-Aug R.GIFEPFGR.L "sp|Q14498|RBM39_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 5 921.4709 1.38 23140 17932 2 921.47411 461.7427 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 6 3514.3 - 2.49E+06 - - - 3.5357 - 1.511 0.137 - 209.7 1 2 0 0.0033 8 0 0 0 1.52E+08 1.10E+08 - - - 1.2968 0.9925 230117_WJC_METTL3_WT_vs_EV_F03.17933.17933.2 0.101 14-Aug K.NILTEIYR[166.11].L sp|Q15907|RB11B_HUMAN 1 1030.5687 1.72 23141 17933 2 1030.573145 516.2916 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 6 3514.3 - 2.36E+06 - - - 4.3471 - 1.55 0.205 - 248.6 1 2 0 0.0045 8 0 0 0 5.40E+07 3.14E+07 - - - 1.8755 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.17935.17935.2 0.251 18-Nov K.EVLLVALGSR.Q sp|Q10570|CPSF1_HUMAN 1 1055.6339 1.55 23143 17935 2 1055.636168 528.8242 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6.1 3514.5 - 600159 - - - 2.1532 - 2.118 0.237 - 384.4 1 2 0 0.0023 10 0 0 0 2.60E+07 1.68E+07 - - - 2.8856 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.17937.17937.2 0.000437 18-Oct R.LITTQQWLIK.L sp|P00846|ATP6_HUMAN 1 1242.7336 1.3 23145 17937 2 1242.738204 622.3741 ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1 8.75 3514.7 - 519160 - - - 3.6975 - 1.887 0.428 - 213.6 1 2 0 0.0046 10 0 0 0 1.59E+07 1.22E+07 - - - 3.9732 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.17940.17940.2 0.00381 16-Sep R.AVALYFIDK[136.11].L "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN,tr|E5RIC7|E5RIC7_HUMAN" 4 1046.5892 0.3 23147 17940 2 1046.593169 524.3019 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 5.88 3515.1 - 3.95E+06 - - - 3.8086 - 1.867 0.394 - 285.2 1 2 0 0.004 9 0 0 0 1.82E+07 5.98E+07 - - - 3.7561 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.17943.17943.2 2.79E-05 20-Aug R.AVVPSYIPLVK[136.11].K sp|P36551|HEM6_HUMAN 1 1192.7311 1.1 23149 17943 2 1192.735528 597.3728 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3515.4 - 6.34E+06 - - - 3.7158 - 1.956 0.357 - 212.1 1 2 0 0.0044 11 0 0 0 3.21E+08 2.91E+08 - - - 3.4914 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.17944.17944.2 4.20E-06 20-Sep R.AVVPSYIPLVK.K sp|P36551|HEM6_HUMAN 1 1184.7169 1.1 23150 17944 2 1184.721776 593.3657 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3515.4 - 5.64E+06 - - - 4.1191 - 1.88 0.415 - 290.9 1 2 0 0.0049 11 0 0 0 3.21E+08 2.91E+08 - - - 3.8124 0.9946 230117_WJC_METTL3_WT_vs_EV_F03.17945.17945.2 1.58 14-Sep K.ILILQGLK.Q "sp|Q9UNX4|WDR3_HUMAN,tr|D6RCT0|D6RCT0_HUMAN" 2 896.6059 1.03 23151 17945 2 896.608927 449.3102 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 8.75 3515.5 - 1.94E+06 - - - 3.3883 - 1.736 0.12 - 214 1 2 0 0.003 8 0 0 0 3.01E+07 2.93E+07 - - - 1.5899 0.9956 230117_WJC_METTL3_WT_vs_EV_F03.17946.17946.2 0.181 14-Aug R.ADLIAYLK[136.11].K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 913.5364 1.4 23152 17946 2 913.539708 457.7755 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 5.88 3515.6 - 1.52E+06 - - - 3.6003 - 1.859 0.133 - 172.5 1 2 0 0.0033 8 0 0 0 3.76E+07 2.68E+07 - - - 1.8923 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.17947.17947.3 0.0869 15/36 R.FSVLLLHGIR.F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1153.6972 2.4 23153 17947 3 1153.700867 385.573 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3515.7 - 1.03E+06 - - - 3.2097 - 2.317 0.402 - 262.7 1 2 0 0.0037 10 0 0 0 1.29E+07 5.39E+06 - - - 5.4748 0.999 230117_WJC_METTL3_WT_vs_EV_F03.17948.17948.2 0.0193 18-Oct R.LITTQQWLIK[136.11].L sp|P00846|ATP6_HUMAN 1 1250.7478 1.3 23154 17948 2 1250.752642 626.3812 ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1 8.75 3515.8 - 871322 - - - 3.8641 - 1.965 0.422 - 253.6 1 2 0 0.0048 10 0 0 0 1.59E+07 1.22E+07 - - - 4.0419 0.999 230117_WJC_METTL3_WT_vs_EV_F03.17949.17949.2 0.000146 22-Nov R.IGPLSPFTNAYR[166.11].R "sp|O75486|SUPT3_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 2 1344.7066 1.52 23155 17949 2 1344.711719 673.3606 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 8.75 3516 - 630890 - - - 3.8395 - 2.195 0.403 - 238.8 1 2 0 0.0052 12 0 0 0 3.69E+07 2.42E+07 - - - 4.0845 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.17950.17950.2 0.534 18-Oct K.VLALLDVPDK.S sp|Q9NX62|IMPA3_HUMAN 1 1081.6383 0.96 23156 17950 2 1081.642876 541.8264 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.21 3516.1 - 603423 - - - 4.2204 - 2.101 0.186 - 288.9 1 2 0 0.0046 10 0 0 0 6.61E+07 6.89E+07 - - - 2.4857 1 230117_WJC_METTL3_WT_vs_EV_F03.17951.17951.3 1.26E-08 16/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 4.18 23157 17951 3 2187.050814 730.0199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3516.2 - 522295 - - - 5.9203 - 3.122 0.583 - 134.5 1 2 0 0.0129 20 0 0 0 1.29E+07 3.08E+06 - - - 7.7983 1 230117_WJC_METTL3_WT_vs_EV_F03.17958.17958.2 2.63E-06 14/18 R.IC[160.03]DDELILIK.N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1230.653 9.34 23162 17958 2 1230.656726 616.3338 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3517.1 - 9.55E+06 - - - 3.0472 - 2.757 0.451 - 550.8 1 2 0 0.0037 10 0 0 0 1.30E+09 1.39E+08 - - - 5.2017 0.9947 230117_WJC_METTL3_WT_vs_EV_F03.17959.17959.2 0.00103 20-Oct R.LLALNSLYSPK.L sp|P78527|PRKDC_HUMAN 1 1217.702 1.22 23163 17959 2 1217.709415 609.8583 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.59 3517.1 - 1.71E+06 - - - 6.1107 - 2.116 0.366 - 261.5 1 2 0 0.0074 11 0 0 0 8.68E+07 7.11E+07 - - - 3.7696 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.17960.17960.2 0.00358 18-Oct K.VLALLDVPDK[136.11].S sp|Q9NX62|IMPA3_HUMAN 1 1089.6525 0.96 23164 17960 2 1089.655764 545.8335 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.21 3517.2 - 1.44E+06 - - - 2.9854 - 2.154 0.203 - 260.4 1 2 0 0.0033 10 0 0 0 6.63E+07 6.89E+07 - - - 2.6812 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.17967.17967.2 8.97E-06 18-Nov R.IC[160.03]DDELILIK[136.11].N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1238.6672 9.34 23169 17967 2 1238.670421 620.3409 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3518 - 2.38E+06 - - - 2.6198 - 2.561 0.344 - 251.5 1 2 0 0.0032 10 0 0 0 1.30E+09 1.39E+08 - - - 4.2057 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.17974.17974.2 0.64 14-Jul K.ILILQGLK[136.11].Q "sp|Q9UNX4|WDR3_HUMAN,tr|D6RCT0|D6RCT0_HUMAN" 2 904.6201 1.03 23174 17974 2 904.622234 453.3173 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 8.75 3518.9 - 1.55E+06 - - - 2.3712 - 1.521 0.251 - 105.1 1 2 0 0.0021 8 0 0 0 3.01E+07 2.93E+07 - - - 2.159 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.17977.17977.2 0.0122 16-Aug R.LLESMIPIK[136.11].M "sp|Q9GZM5|YIPF3_HUMAN,tr|D6RGY8|D6RGY8_HUMAN,tr|E7EQR8|E7EQR8_HUMAN,tr|H0Y9A1|H0Y9A1_HUMAN,tr|D6RFI3|D6RFI3_HUMAN" 5 1050.6239 1.41 23177 17977 2 1050.627629 526.3192 Protein YIPF3 OS=Homo sapiens OX=9606 GN=YIPF3 PE=1 SV=1 6 3519 - 1.23E+06 - - - 3.5931 - 1.69 0.368 - 143.9 1 2 0 0.0038 9 0 0 0 3.04E+07 2.16E+07 - - - 3.2759 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.17978.17978.2 5.24E-07 20-Sep K.VLTPELYAELR.A "sp|P12277|KCRB_HUMAN,tr|G3V461|G3V461_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 3 1302.7184 0.82 23178 17978 2 1302.719783 652.3665 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.53 3519.1 - 1.05E+06 - - - 1.0977 - 2.234 0.326 - 337.6 1 2 0 0.0014 11 0 0 0 7.26E+07 8.87E+07 - - - 3.6228 1 230117_WJC_METTL3_WT_vs_EV_F03.17981.17981.3 5.29E-10 15/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 4.18 23181 17981 3 2197.049524 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3519.5 - 259487 - - - 1.5421 - 2.782 0.627 - 210.2 1 2 0 0.0034 20 0 0 0 1.29E+07 3.08E+06 - - - 8.0117 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.17984.17984.2 0.0121 16-Aug R.SSIAGLLLK.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 900.5644 3.66 23182 17984 2 900.566154 451.2895 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.47 3519.9 - 1.66E+06 - - - 1.9277 - 1.743 0.274 - 147.3 1 2 0 0.0017 9 0 0 0 4.40E+07 1.20E+07 - - - 2.6716 0.984 230117_WJC_METTL3_WT_vs_EV_F03.17985.17985.2 2.85 14-Jul R.DVDFELIK.V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 977.507 3.78 23183 17985 2 977.510293 489.7608 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3519.9 - 1.97E+06 - - - 3.4066 - 1.24 0.143 - 142.1 1 2 0 0.0033 8 0 0 0 1.25E+09 3.31E+08 - - - 0.7449 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.17991.17991.2 0.494 12-Aug K.FLELLPK.D "sp|P63010|AP2B1_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 5 858.5215 1.6 23189 17991 2 858.522348 430.268 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 6 3520.5 - 357823 - - - 0.9982 - 1.266 0.235 - 166 1 2 0 0.0009 7 0 0 0 3.92E+07 2.45E+07 - - - 1.5238 0.999 230117_WJC_METTL3_WT_vs_EV_F03.17994.17994.2 0.0102 14-Aug R.LFGALLER[166.11].G sp|Q9BVI4|NOC4L_HUMAN 1 927.5417 1.05 23190 17994 2 927.543773 464.7781 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3520.9 - 6.34E+06 - - - 2.2112 - 1.829 0.241 - 205.1 1 2 0 0.0021 8 0 0 0 1.23E+08 1.17E+08 - - - 2.6413 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.17995.17995.2 0.0492 14-Aug K.IDHILDAL.- "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 908.4967 - 23191 17995 2 908.499009 455.2556 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.2 3521 - 2.38E+06 - - - 2.5052 - 1.543 0.182 - 171.5 1 2 0 0.0023 8 0 0 0 - - - - - 1.6926 1 230117_WJC_METTL3_WT_vs_EV_F03.17996.17996.2 4.20E-05 18-Oct R.VVYIFGPPVK.E sp|P49915|GUAA_HUMAN 1 1117.6536 3.69 23192 17996 2 1117.656475 559.8341 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 8.56 3521.1 - 1.70E+06 - - - 2.601 - 2.06 0.478 - 435.6 1 2 0 0.0029 10 0 0 0 3.62E+07 9.81E+06 - - - 4.5879 0.9704 230117_WJC_METTL3_WT_vs_EV_F03.17997.17997.2 0.00249 12-May K.ILFFNDK.S sp|P29084|T2EB_HUMAN 1 895.4804 2.93 23193 17997 2 895.486411 448.7475 Transcription initiation factor IIE subunit beta OS=Homo sapiens OX=9606 GN=GTF2E2 PE=1 SV=1 5.84 3521.2 - 1.56E+06 - - - 6.764 - 1.227 0.325 - 67.9 1 2 0 0.0061 7 0 0 0 3.37E+07 1.15E+07 - - - 2.0877 0.9162 230117_WJC_METTL3_WT_vs_EV_F03.18000.18000.2 0.021 16-Jul K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 66.62 23196 18000 2 1014.538563 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3521.5 - 526250 - - - 3.9309 - 1.331 0.022 - 87.7 3 2 0 0.004 9 0 0 0 9.02E+06 1.35E+05 - - - -0.1837 1 230117_WJC_METTL3_WT_vs_EV_F03.18001.18001.2 5.52E-05 20-Sep R.FPC[160.03]VVYINEVR.V sp|Q69YN4|VIR_HUMAN 1 1394.7017 2.4 23197 18001 2 1394.701877 698.3581 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 5.99 3521.6 - 321691 - - - 0.1577 - 1.947 0.535 - 357.1 1 2 0 0.0002 11 0 0 0 5.14E+06 2.14E+06 - - - 4.7949 1 230117_WJC_METTL3_WT_vs_EV_F03.18002.18002.2 3.24E-12 14/38 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 19.66 23198 18002 2 2187.042336 1094.5262 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3521.8 - 238969 - - - 2.0439 - 2.979 0.755 - 381.7 1 2 0 0.0045 20 0 0 0 3.11E+06 1.58E+05 - - - 7.2997 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.18008.18008.2 0.00622 14-Oct R.LFGALLER.G sp|Q9BVI4|NOC4L_HUMAN 1 917.5335 1.03 23202 18008 2 917.536374 459.774 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3522.4 - 8.35E+06 - - - 3.1846 - 1.858 0.217 - 286.8 1 2 0 0.0029 8 0 0 0 1.33E+08 1.29E+08 - - - 2.5112 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.18012.18012.2 0.289 16-Aug R.VILLENLTR.F "sp|Q14999|CUL7_HUMAN,tr|A0A669KB95|A0A669KB95_HUMAN,tr|A0A669KAU7|A0A669KAU7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 4 1069.6495 1.56 23206 18012 2 1069.652589 535.832 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 5.97 3522.7 - 957636 - - - 2.8458 - 1.645 0.304 - 171 1 2 0 0.003 9 0 0 0 2.06E+07 1.32E+07 - - - 2.7254 1 230117_WJC_METTL3_WT_vs_EV_F03.18015.18015.2 1.50E-05 14/22 K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 999 23209 18015 2 1474.750225 738.3781 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3523.1 - 383164 - - - 5.8437 - 2.851 0.58 - 831.3 1 2 0 0.0086 12 0 0 0 6.71E+06 0.00E+00 - - - 6.0788 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18017.18017.2 0.0513 22-Sep R.LLQTIAVLEAQR.S sp|Q8IYH5|ZZZ3_HUMAN 1 1353.798 5.2 23211 18017 2 1353.797389 677.9063 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 6 3523.4 - 347070 - - - -0.4513 - 2.275 0.368 - 296.5 1 2 0 -0.0006 12 0 0 0 4.76E+06 9.16E+05 - - - 3.9216 0.97 230117_WJC_METTL3_WT_vs_EV_F03.18024.18024.2 0.638 14-Jun K.IISLDAWR.V "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 972.5393 2.14 23216 18024 2 972.539756 487.2769 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.84 3524.1 - 683090 - - - 0.5038 - 1.364 0.023 - 70.2 5 2 0 0.0005 8 0 0 0 4.50E+07 2.11E+07 - - - -0.1653 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.18026.18026.2 6.24E-05 20-Nov R.LLMLGLDNAGK.T "sp|P36404|ARL2_HUMAN,tr|V9GYD0|V9GYD0_HUMAN" 2 1143.6322 2.85 23218 18026 2 1143.637825 572.8234 ADP-ribosylation factor-like protein 2 OS=Homo sapiens OX=9606 GN=ARL2 PE=1 SV=4 5.84 3524.4 - 311447 - - - 4.936 - 2.058 0.439 - 268.7 1 2 0 0.0056 11 0 0 0 5.01E+06 1.76E+06 - - - 4.2341 0.9631 230117_WJC_METTL3_WT_vs_EV_F03.18032.18032.2 0.0443 14-Jun R.QMFLATWK.D sp|Q10567|AP1B1_HUMAN 1 1023.5212 0.39 23222 18032 2 1023.526611 512.7679 AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2 8.75 3525 - 715103 - - - 5.313 - 1.297 0.169 - 95.1 1 2 0 0.0054 8 0 0 0 7.68E+06 1.95E+07 - - - 1.0718 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18036.18036.2 0.00159 20-Sep R.IVLLDSSLEYK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1278.7071 18.9 23225 18036 2 1278.709907 640.3608 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3525.6 - 725895 - - - 2.1803 - 2.144 0.44 - 199.9 1 2 0 0.0028 11 0 0 0 1.49E+07 7.88E+05 - - - 4.3532 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18038.18038.2 0.0121 18-Aug R.VVYIFGPPVK[136.11].E sp|P49915|GUAA_HUMAN 1 1125.6678 4.07 23226 18038 2 1125.670508 563.8412 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 8.56 3525.9 - 645224 - - - 2.4341 - 1.754 0.337 - 140.2 1 2 0 0.0027 10 0 0 0 3.05E+07 7.50E+06 - - - 3.0977 0.987 230117_WJC_METTL3_WT_vs_EV_F03.18039.18039.2 0.292 16-Aug R.VVLPYLVPK.L sp|Q92616|GCN1_HUMAN 1 1026.6478 1.14 23227 18039 2 1026.652199 514.3312 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.56 3526 - 901585 - - - 4.3296 - 1.238 0.234 - 175.6 1 2 0 0.0044 9 0 0 0 5.22E+07 4.57E+07 - - - 1.3856 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.18048.18048.2 4.21 12-Sep R.LLDFLQK.R "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 875.5117 1.39 23235 18048 2 875.513743 438.7631 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.84 3527 - 3.56E+06 - - - 2.386 - 1.634 0.152 - 208.7 1 2 0 0.0021 7 0 0 0 9.42E+07 6.79E+07 - - - 1.7189 1 230117_WJC_METTL3_WT_vs_EV_F03.18049.18049.2 4.68E-07 22-Dec K.LFVTNDAATILR[166.11].E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1342.7484 7.74 23236 18049 2 1342.7515 672.3815 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3527.1 - 1.55E+06 - - - 2.2931 - 2.543 0.512 - 472.2 1 2 0 0.0031 12 0 0 0 4.24E+09 5.48E+08 - - - 5.2775 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.18050.18050.2 5.68E-05 16-Oct R.LSMMLLDSR[166.11].A "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1074.5441 4.05 23237 18050 2 1074.549221 538.2793 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.84 3527.2 - 908717 - - - 4.7592 - 2.032 0.424 - 380.7 1 2 0 0.0051 9 0 0 0 8.91E+07 2.20E+07 - - - 4.2223 0.8969 230117_WJC_METTL3_WT_vs_EV_F03.18056.18056.2 0.0456 12-Jul H.ILLWDTR[166.11].N "sp|Q9BTV6|DPH7_HUMAN,sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 3 925.5261 0.44 23241 18056 2 925.527604 463.7703 Diphthine methyltransferase OS=Homo sapiens OX=9606 GN=DPH7 PE=1 SV=2 5.84 3527.9 - 4.24E+06 - - - 1.6553 - 1.564 0.214 - 189.2 1 1 0 0.0015 7 0 0 0 6.19E+08 1.40E+09 - - - 2.0382 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18057.18057.2 0.0108 14-Aug K.LDYILGLK[136.11].L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 941.5677 0.79 23242 18057 2 941.569693 471.7911 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3527.9 - 3.01E+06 - - - 2.0965 - 1.747 0.312 - 187.1 1 2 0 0.002 8 0 0 0 3.57E+08 4.54E+08 - - - 3.0274 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.18062.18062.2 0.689 14-Aug R.DVDFELIK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 985.5212 5.11 23246 18062 2 985.522898 493.7679 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3528.5 - 7.21E+06 - - - 1.7605 - 1.45 0.26 - 168.5 1 2 0 0.0017 8 0 0 0 1.20E+09 2.35E+08 - - - 2.0814 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18065.18065.2 0.0168 14-Sep K.LDYILGLK.L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 933.5535 0.79 23248 18065 2 933.555347 467.784 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3528.8 - 3.21E+06 - - - 1.9581 - 1.907 0.302 - 268.8 1 2 0 0.0018 8 0 0 0 3.57E+08 4.54E+08 - - - 3.2179 0.9876 230117_WJC_METTL3_WT_vs_EV_F03.18068.18068.2 0.409 20-Jun K.YGLLPSHASYL.- sp|Q86U90|YRDC_HUMAN 1 1219.6237 - 23251 18068 2 1219.626373 610.8191 "YrdC domain-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=YRDC PE=1 SV=1" 6.74 3529 - 636936 - - - 2.172 - 1.036 0.176 - 57.8 1 2 0 0.0026 11 0 0 0 - - - - - 0.4358 0.9936 230117_WJC_METTL3_WT_vs_EV_F03.18074.18074.2 0.058 13/18 K.LAVNMVPFPR[166.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1152.6353 3.2 23255 18074 2 1152.641255 577.3249 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3529.8 - 792005 - - - 5.1621 - 1.782 0.263 - 326.7 1 2 0 0.006 10 0 0 0 7.90E+08 2.47E+08 - - - 2.5943 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.18076.18076.2 0.273 14-Sep R.LLILMEAR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 957.5681 1.45 23256 18076 2 957.568552 479.7913 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6 3530 - 1.31E+06 - - - 0.448 - 1.856 0.215 - 267.3 1 2 0 0.0004 8 0 0 0 4.58E+07 3.17E+07 - - - 2.494 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18078.18078.3 0.042 14/44 K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 8.48 23258 18078 3 1332.744672 445.254 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3530.2 - 5.38E+06 - - - 3.3923 - 2.022 0.344 - 255.1 1 2 0 0.0045 12 0 0 0 1.55E+08 1.83E+07 - - - 4.3256 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18079.18079.2 0.000509 18-Aug K.IVLLMAYSGK.G "sp|Q9Y606|TRUA_HUMAN,tr|G8JLB3|G8JLB3_HUMAN,tr|F8W9U5|F8W9U5_HUMAN,tr|F5H168|F5H168_HUMAN,tr|F5H1B2|F5H1B2_HUMAN,tr|F5GY32|F5GY32_HUMAN,tr|F5GXL3|F5GXL3_HUMAN" 7 1093.6206 8.4 23259 18079 2 1093.622401 547.8176 tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3 8.59 3530.3 - 871818 - - - 1.6898 - 1.553 0.404 - 100.5 1 2 0 0.0018 10 0 0 0 1.94E+07 2.31E+06 - - - 3.2531 0.9814 230117_WJC_METTL3_WT_vs_EV_F03.18089.18089.2 1.18 20-Jun R.TINMQQSQVEK.Y "sp|Q8N6V9|TEX9_HUMAN,tr|H3BS88|H3BS88_HUMAN,tr|H0YLZ3|H0YLZ3_HUMAN" 3 1304.6395 5.74 23267 18089 2 1304.64244 653.327 Testis-expressed protein 9 OS=Homo sapiens OX=9606 GN=TEX9 PE=1 SV=1 5.66 3531.6 - 335434 - - - 2.2911 - 1.429 0.068 - 134.8 5 2 0 0.003 11 0 0 0 8.44E+06 1.47E+06 - - - 0.1958 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18094.18094.2 0.00022 14-Oct R.VVDLLVIK.G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 897.5899 2.01 23270 18094 2 897.590927 449.8022 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3532.2 - 5.03E+06 - - - 1.1386 - 1.812 0.43 - 290.6 1 2 0 0.001 8 0 0 0 1.22E+08 6.07E+07 - - - 4.0094 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18096.18096.2 0.00315 18-Sep K.YLAIAPPIIK.Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1097.6849 1.92 23272 18096 2 1097.686717 549.8497 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3532.3 - 2.31E+06 - - - 1.6845 - 1.651 0.369 - 284.4 1 2 0 0.0018 10 0 0 0 1.78E+08 9.30E+07 - - - 3.1654 0.9028 230117_WJC_METTL3_WT_vs_EV_F03.18098.18098.2 4.43 12-May R.SLSDLFR[166.11].R "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 846.4475 0.94 23274 18098 2 846.449326 424.231 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 5.55 3532.5 - 594488 - - - 2.1714 - 1.042 0.015 - 79.4 3 2 0 0.0018 7 0 0 0 2.19E+07 2.33E+07 - - - -0.9316 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.18099.18099.2 0.00244 16-Aug K.WEGNYLFPR[166.11].E "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 1190.5748 0.95 23275 18099 2 1190.575568 596.2947 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3532.6 - 557121 - - - 0.6341 - 1.557 0.288 - 176.5 1 2 0 0.0008 9 0 0 0 7.43E+06 7.82E+06 - - - 2.4489 0.9238 230117_WJC_METTL3_WT_vs_EV_F03.18100.18100.2 4.22 16-Jul R.NFFGPEFVK.M sp|Q12923|PTN13_HUMAN 1 1083.5389 0.33 23276 18100 2 1083.540654 542.7767 Tyrosine-protein phosphatase non-receptor type 13 OS=Homo sapiens OX=9606 GN=PTPN13 PE=1 SV=2 6 3532.7 - 354634 - - - 1.5892 - 0.96 0.029 - 87.1 1 2 0 0.0017 9 0 0 0 8.32E+06 2.50E+07 - - - -0.8634 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18102.18102.2 0.0082 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 1325.9 23277 18102 2 1006.571087 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3532.9 - 3.25E+07 - - - 1.1812 - 1.924 0.475 - 255 1 2 0 0.0012 9 0 0 0 6.04E+08 4.55E+05 - - - 4.4422 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18104.18104.2 0.00691 16-Sep K.VLEALQVLR.C "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1039.639 1.3 23278 18104 2 1039.640598 520.8268 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.97 3533.1 - 3.75E+06 - - - 1.5563 - 1.854 0.386 - 270.9 1 2 0 0.0016 9 0 0 0 4.17E+07 3.22E+07 - - - 3.6775 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18105.18105.2 0.0118 16-Aug K.LFLVQLQEK.A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1116.6543 1.08 23279 18105 2 1116.657097 559.3344 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3533.2 - 2.97E+06 - - - 2.5084 - 1.767 0.352 - 202.4 1 2 0 0.0028 9 0 0 0 3.73E+07 3.45E+07 - - - 3.287 0.9697 230117_WJC_METTL3_WT_vs_EV_F03.18106.18106.2 4.27 16-Jun R.VVLPYLVPK[136.11].L sp|Q92616|GCN1_HUMAN 1 1034.662 1.17 23280 18106 2 1034.663116 518.3383 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.56 3533.3 - 3.45E+06 - - - 1.1231 - 1.076 0.123 - 90.4 9 2 0 0.0012 9 0 0 0 5.37E+07 4.58E+07 - - - -0.2652 1 230117_WJC_METTL3_WT_vs_EV_F03.18107.18107.2 9.45E-05 20-Dec K.LIVAYVDDLDR.R "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1290.682 1.63 23281 18107 2 1290.682887 646.3483 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 3.93 3533.4 - 1.00E+06 - - - 0.7128 - 2.135 0.504 - 598.5 1 2 0 0.0009 11 0 0 0 9.90E+06 6.08E+06 - - - 4.8151 0.935 230117_WJC_METTL3_WT_vs_EV_F03.18109.18109.2 11.9 12-Jun R.SLSDLFR.R "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 836.4392 0.94 23283 18109 2 836.438935 419.2269 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 5.55 3533.7 - 816584 - - - -0.3383 - 1.163 0.01 - 136.2 1 2 0 -0.0003 7 0 0 0 2.19E+07 2.33E+07 - - - -0.4068 1 230117_WJC_METTL3_WT_vs_EV_F03.18110.18110.2 3.63E-07 16/30 R.IINEPTAAAIAYGLDK.R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1658.8879 30.87 23284 18110 2 1658.893951 830.4512 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3533.8 - 796829 - - - 3.6253 - 2.632 0.534 - 467.8 1 2 0 0.006 16 0 0 0 2.25E+07 7.29E+05 - - - 5.3625 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18116.18116.2 0.00315 14-Sep R.YQDILVFR.S "sp|P19623|SPEE_HUMAN,tr|K7EKM4|K7EKM4_HUMAN" 2 1052.5655 6.55 23288 18116 2 1052.567064 527.29 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.84 3534.5 - 2.69E+06 - - - 1.5039 - 1.928 0.441 - 243.7 1 2 0 0.0016 8 0 0 0 1.21E+08 1.85E+07 - - - 4.2777 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.18119.18119.2 0.444 12-Jul R.GWLNIVR.H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 856.4919 1.72 23291 18119 2 856.493213 429.2532 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 9.75 3534.8 - 889782 - - - 1.5073 - 1.321 0.208 - 276 1 2 0 0.0013 7 0 0 0 2.37E+07 1.37E+07 - - - 1.459 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18123.18123.2 0.00115 14-Nov R.VVDLLVIK[136.11].G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 905.6041 2.02 23293 18123 2 905.604812 453.8093 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3535.3 - 3.66E+06 - - - 0.7807 - 1.898 0.478 - 352.9 1 2 0 0.0007 8 0 0 0 1.23E+08 6.08E+07 - - - 4.5039 0.9392 230117_WJC_METTL3_WT_vs_EV_F03.18127.18127.2 0.716 12-Jul R.ALLFIPR.R "sp|P08238|HS90B_HUMAN,sp|O00585|CCL21_HUMAN,tr|Q5VZ73|Q5VZ73_HUMAN" 3 828.5222 2.02 23297 18127 2 828.520102 415.2684 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 9.79 3535.7 - 827823 - - - -2.4827 - 1.452 0.042 - 189.1 1 2 0 -0.0021 7 0 0 0 4.62E+08 2.29E+08 - - - 0.5323 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.18128.18128.2 0.00805 18-Jul K.FYALDPSFPR.M sp|Q08J23|NSUN2_HUMAN 1 1211.5975 1.84 23298 18128 2 1211.597164 606.806 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3535.9 - 784044 - - - -0.2847 - 1.355 0.386 - 123.7 1 2 0 -0.0003 10 0 0 0 2.29E+07 1.25E+07 - - - 2.7399 0.987 230117_WJC_METTL3_WT_vs_EV_F03.18129.18129.3 0.17 Jul-36 K.LAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1142.627 2.94 23299 18129 3 1142.628053 381.883 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3536 - 533858 - - - 0.8909 - 1.472 0.15 - 85.3 1 2 0 0.001 10 0 0 0 6.91E+06 2.35E+06 - - - 1.3412 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.18132.18132.2 0.0701 28-Jun R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 6.39 23302 18132 2 1494.917388 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3536.4 - 234146 - - - 0.8248 - 1.408 0.233 - 79.7 2 2 0 0.0012 15 0 0 0 6.55E+06 1.03E+06 - - - 1.4683 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18135.18135.2 0.0228 16-Aug K.ATSILEFYR[166.11].E "sp|P09001|RM03_HUMAN,tr|D6RC14|D6RC14_HUMAN,tr|E7ETU7|E7ETU7_HUMAN,tr|H0Y9G6|H0Y9G6_HUMAN,tr|E9PF06|E9PF06_HUMAN" 5 1108.5792 1.03 23303 18135 2 1108.581182 555.2969 "39S ribosomal protein L3, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL3 PE=1 SV=1" 6.05 3536.8 - 2.61E+06 - - - 1.7608 - 1.523 0.39 - 195.1 1 2 0 0.002 9 0 0 0 3.14E+07 3.06E+07 - - - 3.138 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18137.18137.2 0.00156 18-Sep K.YLAIAPPIIK[136.11].Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1105.6991 1.92 23305 18137 2 1105.700693 553.8568 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3537 - 4.40E+06 - - - 1.4697 - 1.814 0.468 - 231.5 1 2 0 0.0016 10 0 0 0 1.77E+08 9.23E+07 - - - 4.1595 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18138.18138.2 0.000317 16-Aug K.LLQDFFNGK.E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1080.5604 8.88 23306 18138 2 1080.562522 541.2875 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3537.1 - 3.86E+06 - - - 1.9684 - 1.604 0.39 - 153.3 1 2 0 0.0021 9 0 0 0 9.58E+07 1.08E+07 - - - 3.2878 0.9931 230117_WJC_METTL3_WT_vs_EV_F03.18145.18145.2 0.000266 18-Jul K.FYALDPSFPR[166.11].M sp|Q08J23|NSUN2_HUMAN 1 1221.6058 1.8 23313 18145 2 1221.601316 611.8102 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3538 - 359339 - - - -3.6534 - 1.439 0.437 - 154.7 1 2 0 -0.0045 10 0 0 0 2.26E+07 1.26E+07 - - - 3.2832 0.9865 230117_WJC_METTL3_WT_vs_EV_F03.18146.18146.3 0.405 Oct-36 R.NLIAPIFLHR.T "sp|Q15022|SUZ12_HUMAN,tr|J3QQW9|J3QQW9_HUMAN" 2 1192.7081 1.58 23314 18146 3 1192.709448 398.5766 Polycomb protein SUZ12 OS=Homo sapiens OX=9606 GN=SUZ12 PE=1 SV=3 9.76 3538.1 - 344397 - - - 1.1612 - 1.539 0.136 - 76.9 1 2 0 0.0014 10 0 0 0 2.92E+06 1.84E+06 - - - 1.315 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.18149.18149.2 1.36 14-Jul R.LLILMEAR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 967.5764 1.44 23316 18149 2 967.577718 484.7955 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6 3538.5 - 195814 - - - 1.3694 - 1.645 0.232 - 159.5 1 2 0 0.0013 8 0 0 0 4.58E+07 3.17E+07 - - - 2.2553 0.9791 230117_WJC_METTL3_WT_vs_EV_F03.18151.18151.2 0.00658 16-Sep R.LIDFLEC[160.03]GK[136.11].T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1101.562 0.83 23317 18151 2 1101.555544 551.7883 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3538.7 - 9.32E+06 - - - -5.8444 - 1.862 0.385 - 210.4 1 2 0 -0.0064 9 0 0 0 1.44E+08 1.73E+08 - - - 3.6811 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.18152.18152.2 0.0377 12-Jun R.AVFWDIK[136.11].N sp|Q6P2Q9|PRP8_HUMAN 1 885.484 1.18 23318 18152 2 885.485203 443.7493 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3538.8 - 4.79E+06 - - - 1.3699 - 1.209 0.299 - 158.1 1 2 0 0.0012 7 0 0 0 8.18E+07 6.91E+07 - - - 1.8504 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18153.18153.2 0.00516 18-Oct R.VLITTDLLAR.G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 1113.6758 1.48 23319 18153 2 1113.677231 557.8452 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3538.8 - 1.03E+07 - - - 1.3209 - 2.088 0.449 - 424.7 1 2 0 0.0015 10 0 0 0 2.86E+08 1.93E+08 - - - 4.4118 0.9925 230117_WJC_METTL3_WT_vs_EV_F03.18154.18154.2 0.142 18-Apr R.VLITTDLLAR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 1123.684 1.48 23320 18154 2 1123.686262 562.8493 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3538.8 - 7.69E+06 - - - 1.9863 - 1.052 0.23 - 43 2 2 0 0.0022 10 0 0 0 2.86E+08 1.93E+08 - - - 0.7461 0.8572 230117_WJC_METTL3_WT_vs_EV_F03.18159.18159.2 0.000123 20-Sep Y.LVPILTQTLTK.Q sp|Q14974|IMB1_HUMAN 1 1225.7646 1.83 23325 18159 2 1225.768377 613.8896 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 8.75 3539.3 - 638218 - - - 3.1017 - 1.657 0.258 - 212.9 1 1 0 0.0038 11 0 0 0 5.82E+06 3.19E+06 - - - 2.3116 0.9545 230117_WJC_METTL3_WT_vs_EV_F03.18160.18160.2 2.11 12-May K.IVIPILK.Y "sp|Q8NCM8|DYHC2_HUMAN,sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|A0A3B3ISP9|A0A3B3ISP9_HUMAN,tr|F6XAQ5|F6XAQ5_HUMAN" 6 794.563 1.11 23326 18160 2 794.563495 398.2888 Cytoplasmic dynein 2 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC2H1 PE=1 SV=4 8.75 3539.4 - 384393 - - - 0.6708 - 1.166 0 - 55.4 1 2 0 0.0005 7 0 0 0 5.88E+06 5.32E+06 - - - -0.4725 1 230117_WJC_METTL3_WT_vs_EV_F03.18162.18162.2 4.13E-05 13/22 K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 7.74 23327 18162 2 1332.742292 667.3774 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3539.6 - 4.40E+07 - - - 1.6065 - 2.647 0.501 - 580.5 1 2 0 0.0021 12 0 0 0 4.23E+09 5.47E+08 - - - 5.302 0.9798 230117_WJC_METTL3_WT_vs_EV_F03.18167.18167.2 0.73 12-Jun R.LVVLPFR[166.11].R sp|Q10570|CPSF1_HUMAN 1 852.5461 2.21 23331 18167 2 852.546882 427.2803 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 9.75 3540.1 - 2.17E+06 - - - 0.9419 - 1.145 0.074 - 122.8 1 2 0 0.0008 7 0 0 0 2.99E+07 1.35E+07 - - - 0.0163 1 230117_WJC_METTL3_WT_vs_EV_F03.18168.18168.2 7.57E-05 13/22 R.APVVAIAVLDGR[166.11].G "sp|Q15334|L2GL1_HUMAN,tr|A0A087WW77|A0A087WW77_HUMAN" 2 1189.7058 1.74 23332 18168 2 1189.700816 595.8602 Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens OX=9606 GN=LLGL1 PE=1 SV=3 5.88 3540.2 - 596752 - - - -4.2128 - 2.809 0.473 - 559.3 1 2 0 -0.005 12 0 0 0 8.61E+06 4.95E+06 - - - 5.2506 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18174.18174.2 0.00475 16-Aug R.LIDFLEC[160.03]GK.T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1093.5478 0.77 23335 18174 2 1093.549662 547.7812 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3541 - 9.29E+06 - - - 1.7192 - 1.562 0.345 - 145.9 1 2 0 0.0019 9 0 0 0 1.47E+08 1.90E+08 - - - 2.8788 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.18175.18175.2 0.06 20-Oct K.LDPGLIMEQVK[136.11].V sp|Q9Y5L4|TIM13_HUMAN 1 1249.6832 2.36 23336 18175 2 1249.687625 625.8489 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3541.1 - 625527 - - - 3.5729 - 1.746 0.274 - 323.8 1 2 0 0.0045 11 0 0 0 1.26E+07 5.34E+06 - - - 2.5711 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.18177.18177.2 0.00833 18-Jul K.MLLAISELNK.N sp|Q9H694|BICC1_HUMAN 1 1130.6369 3.15 23338 18177 2 1130.638705 566.3257 Protein bicaudal C homolog 1 OS=Homo sapiens OX=9606 GN=BICC1 PE=1 SV=2 5.75 3541.2 - 916550 - - - 1.569 - 1.25 0.302 - 117.4 1 2 0 0.0018 10 0 0 0 5.29E+06 1.68E+06 - - - 1.8939 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18184.18184.2 0.0296 13/20 K.LALDVEIATYR.K "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1262.6871 1903.92 23343 18184 2 1262.691461 632.3508 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 3542.1 - 411300 - - - 3.491 - 2.749 0.341 - 879.2 1 2 0 0.0044 11 0 0 0 2.66E+08 1.40E+05 - - - 4.2939 1 230117_WJC_METTL3_WT_vs_EV_F03.18185.18185.2 8.59E-06 14/22 R.FLAVGLVDNTVR[166.11].L sp|Q15393|SF3B3_HUMAN 1 1312.7379 1.13 23344 18185 2 1312.738673 657.3762 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3542.2 - 361562 - - - 0.6224 - 2.434 0.543 - 694.4 1 2 0 0.0008 12 0 0 0 1.02E+08 9.01E+07 - - - 5.3919 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.18188.18188.2 0.00791 12-Jun R.AVFWDIK.N sp|Q6P2Q9|PRP8_HUMAN 1 877.4698 1.15 23346 18188 2 877.470962 439.7422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3542.5 - 3.98E+06 - - - 1.3357 - 1.333 0.357 - 158.7 1 2 0 0.0012 7 0 0 0 8.23E+07 7.15E+07 - - - 2.5882 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18190.18190.2 0.0104 14-Sep R.IGVMSLIR[166.11].K "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 897.5345 1.36 23347 18190 2 897.535889 449.7745 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 3542.8 - 3.20E+06 - - - 1.5153 - 1.639 0.376 - 250.4 1 2 0 0.0014 8 0 0 0 2.94E+07 2.16E+07 - - - 3.3079 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.18191.18191.2 0.17 18-Oct R.ILELDQELIK[136.11].A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1220.7108 1.33 23348 18191 2 1220.710683 611.3627 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3542.9 - 1.42E+06 - - - -0.059 - 2.145 0.198 - 246.6 1 2 0 -0.0001 10 0 0 0 2.77E+07 2.09E+07 - - - 2.6336 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18192.18192.2 0.0491 18-Nov R.ILELDQELIK.A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1212.6966 1.33 23349 18192 2 1212.698776 607.3556 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3543 - 1.59E+06 - - - 1.8315 - 1.936 0.276 - 290.1 1 2 0 0.0022 10 0 0 0 2.77E+07 2.09E+07 - - - 2.9228 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18194.18194.2 0.00534 26-Sep K.VLIPSYAAGSIIGK.G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|F8W659|F8W659_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|F8VYI3|F8VYI3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|I3L2B5|I3L2B5_HUMAN" 8 1387.8075 2.72 23351 18194 2 1387.808821 694.911 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.56 3543.3 - 670903 - - - 0.9504 - 1.565 0.451 - 137.6 1 2 0 0.0013 14 0 0 0 5.72E+06 2.10E+06 - - - 3.4956 0.9519 230117_WJC_METTL3_WT_vs_EV_F03.18196.18196.2 0.118 14-Jul R.FLFPEGIK[136.11].G "sp|O75891|AL1L1_HUMAN,sp|Q3SY69|AL1L2_HUMAN,tr|C9IZ36|C9IZ36_HUMAN,tr|A0A494C1M4|A0A494C1M4_HUMAN" 4 957.5415 1.29 23353 18196 2 957.538413 479.778 Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L1 PE=1 SV=2 6 3543.5 - 455423 - - - -3.2281 - 1.223 0.19 - 110.8 1 2 0 -0.0031 8 0 0 0 1.16E+07 9.01E+06 - - - 1.0505 1 230117_WJC_METTL3_WT_vs_EV_F03.18198.18198.2 4.67E-08 15/24 -.MLSEVLLVSAPGK[136.11].V "sp|Q03426|KIME_HUMAN,tr|F5GXC0|F5GXC0_HUMAN,tr|F5H163|F5H163_HUMAN,tr|F5H092|F5H092_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|F5H368|F5H368_HUMAN,tr|A0A1W2PS16|A0A1W2PS16_HUMAN" 7 1350.7672 12.18 23355 18198 2 1350.767938 676.3909 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 5.75 3543.8 - 378761 - - - 0.5286 - 2.691 0.608 - 697.1 1 2 0 0.0007 13 0 0 0 2.60E+07 2.14E+06 - - - 6.0721 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18199.18199.2 0.000601 28-Sep R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 8.26 23356 18199 2 1484.909031 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3543.9 - 273107 - - - 0.7718 - 1.927 0.412 - 143.1 1 2 0 0.0011 15 0 0 0 3.36E+06 4.07E+05 - - - 3.6964 0.8701 230117_WJC_METTL3_WT_vs_EV_F03.18206.18206.2 0.0223 18-Aug N.MVVDAVLAIK.Y "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1057.6206 14.56 23362 18206 2 1057.623766 529.8176 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.59 3544.8 - 397744 - - - 3.038 - 1.417 0.321 - 149 1 1 0 0.0032 10 0 0 0 2.46E+07 1.69E+06 - - - 2.3838 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.18208.18208.2 0.222 16-Oct K.TLGILGLGR[166.11].L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 908.5683 2.04 23363 18208 2 908.569439 455.2914 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3545 - 3.17E+06 - - - 1.2844 - 1.687 0.144 - 331.6 1 2 0 0.0012 9 0 0 0 3.10E+08 1.52E+08 - - - 1.6171 1 230117_WJC_METTL3_WT_vs_EV_F03.18209.18209.2 7.95E-05 13/20 R.VVGVLLGSWQK.K "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 1184.6917 1.7 23364 18209 2 1184.695794 593.3531 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 8.72 3545.1 - 1.82E+06 - - - 3.4186 - 2.283 0.512 - 556.3 1 2 0 0.004 11 0 0 0 1.95E+07 1.15E+07 - - - 5.0545 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18210.18210.2 0.000648 16-Aug R.YYIDADLLR.E sp|Q7Z3B4|NUP54_HUMAN 1 1140.5815 2.38 23365 18210 2 1140.584763 571.298 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.21 3545.2 - 6.29E+06 - - - 2.8389 - 1.712 0.459 - 200.5 1 2 0 0.0032 9 0 0 0 4.84E+07 2.04E+07 - - - 3.9856 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18211.18211.2 0.0049 14-Aug R.IGVMSLIR.K "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 887.5263 1.37 23366 18211 2 887.528502 444.7704 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 3545.3 - 4.82E+06 - - - 2.5272 - 1.741 0.362 - 155.1 1 2 0 0.0022 8 0 0 0 2.96E+07 2.16E+07 - - - 3.3863 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.18212.18212.2 0.00681 16-Jul R.YYIDADLLR[166.11].E sp|Q7Z3B4|NUP54_HUMAN 1 1150.5898 2.38 23367 18212 2 1150.593577 576.3022 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.21 3545.3 - 2.95E+06 - - - 3.287 - 1.396 0.32 - 133 1 2 0 0.0038 9 0 0 0 4.84E+07 2.04E+07 - - - 2.3685 1 230117_WJC_METTL3_WT_vs_EV_F03.18213.18213.2 0.00042 13/22 K.IPGIIIAASAVR.A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1179.7339 2.4 23368 18213 2 1179.737645 590.8742 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3545.4 - 2.07E+06 - - - 3.138 - 2.465 0.467 - 636.4 1 2 0 0.0037 12 0 0 0 4.54E+07 1.89E+07 - - - 4.8629 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.18214.18214.2 0.00421 14-Aug R.VPTIFPLR[166.11].G sp|Q96EK4|THA11_HUMAN 1 951.5781 28.22 23369 18214 2 951.581037 476.7963 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 9.72 3545.6 - 1.66E+06 - - - 3.078 - 1.6 0.415 - 222.6 1 2 0 0.0029 8 0 0 0 4.09E+08 1.45E+07 - - - 3.5228 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18215.18215.2 0.0045 20-Sep K.LVAASQAALGL.- "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 1012.5917 - 23370 18215 2 1012.59283 507.3031 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.52 3545.7 - 1.57E+06 - - - 1.1199 - 2.034 0.245 - 128.7 1 2 0 0.0011 11 0 0 0 - - - - - 2.7709 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.18216.18216.2 0.0119 20-Nov K.LALDMEISAYR.K "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN" 2 1280.6435 1.55 23371 18216 2 1280.647867 641.329 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.37 3545.8 - 1.41E+06 - - - 3.4311 - 2.44 0.292 - 506.3 1 2 0 0.0044 11 0 0 0 8.08E+06 5.23E+06 - - - 3.6094 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18217.18217.2 0.427 20-Dec R.VVGVLLGSWQK[136.11].K "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 1192.7059 1.7 23372 18217 2 1192.708544 597.3602 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 8.72 3545.9 - 1.33E+06 - - - 2.1799 - 2.237 0.27 - 461.5 1 2 0 0.0026 11 0 0 0 1.95E+07 1.15E+07 - - - 3.2125 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18218.18218.2 0.00934 20-Oct R.LGIPDAVSYIK.K sp|O94874|UFL1_HUMAN 1 1174.6598 2.81 23373 18218 2 1174.663486 588.3372 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.83 3546.1 - 1.28E+06 - - - 3.1592 - 2.14 0.393 - 187.6 1 2 0 0.0037 11 0 0 0 2.34E+07 8.32E+06 - - - 4.0007 0.9584 230117_WJC_METTL3_WT_vs_EV_F03.18222.18222.2 0.00371 26-Dec K.VLIPSYAAGSIIGK[136.11].G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|F8W659|F8W659_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|F8VYI3|F8VYI3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|I3L2B5|I3L2B5_HUMAN" 8 1395.8217 2.77 23377 18222 2 1395.816758 698.9181 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.56 3546.6 - 388003 - - - -3.542 - 1.908 0.09 - 340.4 1 2 0 -0.0049 14 0 0 0 5.72E+06 2.06E+06 - - - 1.3254 0.8658 230117_WJC_METTL3_WT_vs_EV_F03.18226.18226.2 0.0798 12-Aug H.ILLWDTR.N "sp|Q9BTV6|DPH7_HUMAN,sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 3 915.5178 0.44 23380 18226 2 915.519877 458.7662 Diphthine methyltransferase OS=Homo sapiens OX=9606 GN=DPH7 PE=1 SV=2 5.84 3547.2 - 1.22E+06 - - - 2.2665 - 1.509 0.215 - 251.4 1 1 0 0.0021 7 0 0 0 6.19E+08 1.40E+09 - - - 1.932 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.18228.18228.2 15.7 16-Oct K.TLGILGLGR.L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 898.56 2.04 23382 18228 2 898.562829 450.2873 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3547.3 - 1.39E+07 - - - 3.1461 - 1.971 0.158 - 312.2 1 2 0 0.0028 9 0 0 0 3.17E+08 1.55E+08 - - - 2.1702 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18232.18232.2 0.000533 22-Dec K.LIVDPALDPALR.R "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN,tr|C9J2Z9|C9J2Z9_HUMAN" 3 1291.75 2.55 23386 18232 2 1291.75287 646.8823 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.21 3547.7 - 1.14E+06 - - - 2.2319 - 1.787 0.414 - 302.2 1 2 0 0.0029 12 0 0 0 2.56E+07 1.00E+07 - - - 3.6254 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.18234.18234.3 8.81E-05 Nov-44 R.FLAVGLVDNTVR.L sp|Q15393|SF3B3_HUMAN 1 1302.7296 5.26 23388 18234 3 1302.733719 435.2505 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3547.9 - 945439 - - - 3.1726 - 1.926 0.426 - 142.3 1 2 0 0.0041 12 0 0 0 2.17E+07 4.12E+06 - - - 5.1051 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.18236.18236.2 0.578 12-Aug K.ILVDLLK.L "sp|Q6P582|MZT2A_HUMAN,sp|Q6NZ67|MZT2B_HUMAN,tr|H7C202|H7C202_HUMAN,tr|B8ZZ87|B8ZZ87_HUMAN,tr|A0A494C0V9|A0A494C0V9_HUMAN,tr|H7BZ50|H7BZ50_HUMAN,tr|H7C173|H7C173_HUMAN" 7 812.5371 2.35 23390 18236 2 812.539631 407.2758 Mitotic-spindle organizing protein 2A OS=Homo sapiens OX=9606 GN=MZT2A PE=1 SV=2 5.84 3548.1 - 649476 - - - 3.0645 - 1.859 0.222 - 169.5 1 2 0 0.0025 7 0 0 0 1.98E+07 8.40E+06 - - - 2.6445 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.18238.18238.2 8.28E-05 28-Oct R.LGALQGDPEALTLYR.E sp|Q9P253|VPS18_HUMAN 1 1615.857 7.99 23392 18238 2 1615.86296 808.9358 Vacuolar protein sorting-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=VPS18 PE=1 SV=2 4.37 3548.4 - 293658 - - - 3.7058 - 1.972 0.475 - 219.3 1 2 0 0.006 15 0 0 0 1.46E+06 1.83E+05 - - - 4.2169 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.18241.18241.2 0.000525 20-Oct K.LDPGLIMEQVK.V sp|Q9Y5L4|TIM13_HUMAN 1 1241.669 2.36 23394 18241 2 1241.673898 621.8418 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3548.7 - 645375 - - - 3.9769 - 1.867 0.431 - 275.7 1 2 0 0.0049 11 0 0 0 1.26E+07 5.34E+06 - - - 3.9118 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.18245.18245.2 0.0879 12-Aug K.ILVDLLK[136.11].L "sp|Q6P582|MZT2A_HUMAN,sp|Q6NZ67|MZT2B_HUMAN,tr|H7C202|H7C202_HUMAN,tr|B8ZZ87|B8ZZ87_HUMAN,tr|A0A494C0V9|A0A494C0V9_HUMAN,tr|H7BZ50|H7BZ50_HUMAN,tr|H7C173|H7C173_HUMAN" 7 820.5513 2.35 23397 18245 2 820.552589 411.2829 Mitotic-spindle organizing protein 2A OS=Homo sapiens OX=9606 GN=MZT2A PE=1 SV=2 5.84 3549.1 - 635376 - - - 1.5209 - 1.611 0.171 - 144.4 1 2 0 0.0012 7 0 0 0 1.98E+07 8.40E+06 - - - 1.8146 0.9564 230117_WJC_METTL3_WT_vs_EV_F03.18246.18246.2 0.322 12-May K.FALPYIR.D "sp|P06132|DCUP_HUMAN,tr|Q5T446|Q5T446_HUMAN,tr|A0A1B0GVN9|A0A1B0GVN9_HUMAN,tr|H0Y5R6|H0Y5R6_HUMAN,tr|A0A494C0S8|A0A494C0S8_HUMAN,tr|A0A494C0Q8|A0A494C0Q8_HUMAN,tr|A0A494C085|A0A494C085_HUMAN" 7 878.5014 1.46 23398 18246 2 878.503602 440.258 Uroporphyrinogen decarboxylase OS=Homo sapiens OX=9606 GN=UROD PE=1 SV=2 8.75 3549.2 - 441830 - - - 2.4792 - 1.232 0.027 - 77.8 3 2 0 0.0022 7 0 0 0 1.13E+07 7.75E+06 - - - -0.3123 0.9664 230117_WJC_METTL3_WT_vs_EV_F03.18247.18247.2 0.00692 20-Sep R.LLDLVVQPVPR.P sp|Q8WYP5|ELYS_HUMAN 1 1247.7602 1.3 23399 18247 2 1247.762131 624.8874 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.84 3549.4 - 399354 - - - 1.5812 - 1.898 0.361 - 303.4 1 1 0 0.002 11 0 0 0 8.72E+06 6.73E+06 - - - 3.4402 0.9772 230117_WJC_METTL3_WT_vs_EV_F03.18248.18248.2 0.00874 13/22 H.IISELILTAQER[166.11].D sp|Q96I24|FUBP3_HUMAN 1 1394.8009 1.54 23400 18248 2 1394.80321 698.4077 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3549.5 - 370721 - - - 1.692 - 2.467 0.382 - 605.2 1 1 0 0.0024 12 0 0 0 6.93E+06 4.51E+06 - - - 4.2377 0.953 230117_WJC_METTL3_WT_vs_EV_F03.18249.18249.2 0.0417 22-Oct L.PLIPIVVEQTGR.G sp|Q16740|CLPP_HUMAN 1 1320.7765 1.67 23401 18249 2 1320.776133 661.3955 "ATP-dependent Clp protease proteolytic subunit, mitochondrial OS=Homo sapiens OX=9606 GN=CLPP PE=1 SV=1" 6.43 3549.6 - 279768 - - - -0.3051 - 2.081 0.381 - 234 1 1 0 -0.0004 12 0 0 0 5.71E+06 3.42E+06 - - - 3.7832 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18254.18254.2 0.000824 13/22 R.FLAVGLVDNTVR.L sp|Q15393|SF3B3_HUMAN 1 1302.7296 1.13 23405 18254 2 1302.731706 652.3721 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3550.2 - 5.32E+06 - - - 1.6274 - 2.313 0.43 - 524.5 1 2 0 0.0021 12 0 0 0 1.02E+08 9.01E+07 - - - 4.4227 1 230117_WJC_METTL3_WT_vs_EV_F03.18257.18257.2 0.00605 13/22 K.IPGIIIAASAVR[166.11].A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1189.7422 2.4 23408 18257 2 1189.747429 595.8784 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3550.6 - 1.09E+06 - - - 4.3841 - 2.505 0.442 - 623.2 1 2 0 0.0052 12 0 0 0 4.54E+07 1.89E+07 - - - 4.7201 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.18258.18258.2 0.273 16-Nov R.LALILC[160.03]VTK.A sp|P31944|CASPE_HUMAN 1 1029.6256 4.68 23409 18258 2 1029.629704 515.8201 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 8.22 3550.7 - 1.05E+06 - - - 3.948 - 2.008 0.168 - 209.1 1 2 0 0.0041 9 0 0 0 1.12E+07 2.41E+06 - - - 2.2974 1 230117_WJC_METTL3_WT_vs_EV_F03.18259.18259.2 0.00022 14/22 H.IISELILTAQER.D sp|Q96I24|FUBP3_HUMAN 1 1384.7926 1.48 23410 18259 2 1384.798937 693.4036 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3550.8 - 487821 - - - 4.5906 - 2.627 0.457 - 841.4 1 1 0 0.0064 12 0 0 0 7.14E+06 4.81E+06 - - - 4.9557 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18269.18269.2 0.00183 18-Aug R.YLYTLVITDK.E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1227.6751 1.5 23418 18269 2 1227.677709 614.8448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3552 - 1.22E+06 - - - 2.1325 - 1.773 0.325 - 147.4 1 2 0 0.0026 10 0 0 0 4.91E+08 3.28E+08 - - - 3.0391 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.18270.18270.2 0.000152 18-Oct R.YLYTLVITDK[136.11].E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1235.6893 1.5 23419 18270 2 1235.693442 618.8519 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3552.1 - 1.15E+06 - - - 3.3593 - 1.984 0.354 - 259.3 1 2 0 0.0042 10 0 0 0 4.91E+08 3.28E+08 - - - 3.5667 0.8888 230117_WJC_METTL3_WT_vs_EV_F03.18271.18271.2 0.0133 20-Aug R.LLDLVVQPVPR[166.11].P sp|Q8WYP5|ELYS_HUMAN 1 1257.7684 1.3 23420 18271 2 1257.77329 629.8915 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.84 3552.2 - 1.05E+06 - - - 3.8656 - 2.012 0.314 - 267.2 1 1 0 0.0049 11 0 0 0 8.72E+06 6.73E+06 - - - 3.25 0.9913 230117_WJC_METTL3_WT_vs_EV_F03.18273.18273.2 3.11 12-Jul K.MIADFLR[166.11].E "sp|Q96R72|OR4K3_HUMAN,sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 4 874.461 4.24 23422 18273 2 874.463971 438.2378 Olfactory receptor 4K3 OS=Homo sapiens OX=9606 GN=OR4K3 PE=3 SV=3 5.59 3552.4 - 747625 - - - 3.3644 - 1.399 0.146 - 186.5 1 2 0 0.0029 7 0 0 0 4.60E+07 1.08E+07 - - - 1.1823 0.9902 230117_WJC_METTL3_WT_vs_EV_F03.18276.18276.2 0.131 20-Aug K.VMVTNVTSLLK.T "sp|Q9Y4G6|TLN2_HUMAN,sp|Q9Y490|TLN1_HUMAN,tr|A0A1B0GVU7|A0A1B0GVU7_HUMAN,tr|H0YMT1|H0YMT1_HUMAN" 4 1203.6897 0.21 23425 18276 2 1203.693513 602.8521 Talin-2 OS=Homo sapiens OX=9606 GN=TLN2 PE=1 SV=4 8.72 3552.7 - 488566 - - - 3.1719 - 1.248 0.184 - 113.2 1 2 0 0.0038 11 0 0 0 3.28E+06 1.58E+07 - - - 0.9981 0.9768 230117_WJC_METTL3_WT_vs_EV_F03.18277.18277.2 0.123 18-Sep K.VALLDFGATR.E sp|Q8NI60|COQ8A_HUMAN 1 1061.5869 2.49 23426 18277 2 1061.594914 531.8007 "Atypical kinase COQ8A, mitochondrial OS=Homo sapiens OX=9606 GN=COQ8A PE=1 SV=1" 5.81 3552.8 - 461172 - - - 7.5067 - 1.811 0.285 - 249.5 1 2 0 0.008 10 0 0 0 4.93E+06 1.98E+06 - - - 2.8012 0.9094 230117_WJC_METTL3_WT_vs_EV_F03.18279.18279.2 0.0465 18-Aug S.GVAVSDGVIK.V "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PS23|E9PS23_HUMAN" 4 943.5338 1.74 23428 18279 2 943.535455 472.7742 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 5.84 3553 - 532931 - - - 1.7053 - 1.478 0.278 - 114.2 1 1 0 0.0016 10 0 0 0 9.48E+05 5.43E+05 - - - 2.1843 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18285.18285.2 0.000998 16-Aug K.GIFLGDQWR.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1090.556 2.65 23432 18285 2 1090.558482 546.2853 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3553.7 - 5.38E+06 - - - 2.2952 - 1.552 0.499 - 235.1 1 2 0 0.0025 9 0 0 0 8.85E+07 3.34E+07 - - - 3.9975 0.9954 230117_WJC_METTL3_WT_vs_EV_F03.18286.18286.2 0.915 12-Jun K.MIADFLR.E "sp|Q96R72|OR4K3_HUMAN,sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 4 864.4528 4.07 23433 18286 2 864.45501 433.2337 Olfactory receptor 4K3 OS=Homo sapiens OX=9606 GN=OR4K3 PE=3 SV=3 5.59 3553.8 - 1.99E+06 - - - 2.604 - 1.338 0.185 - 168.6 1 2 0 0.0022 7 0 0 0 4.62E+07 1.14E+07 - - - 1.3293 0.999 230117_WJC_METTL3_WT_vs_EV_F03.18288.18288.2 0.00603 20-Oct R.ILDVGFEEELK[136.11].Q "sp|Q9NVP1|DDX18_HUMAN,tr|H7C452|H7C452_HUMAN" 2 1298.6849 0.99 23435 18288 2 1298.68946 650.3497 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 4 3554.1 - 1.46E+06 - - - 3.4851 - 1.879 0.383 - 308.5 1 2 0 0.0045 11 0 0 0 9.70E+06 9.78E+06 - - - 3.5747 0.9864 230117_WJC_METTL3_WT_vs_EV_F03.18297.18297.2 0.211 14-Jul K.IGGIFAFK.V "sp|P22307|SCP2_HUMAN,tr|H0YF61|H0YF61_HUMAN" 2 851.4905 1.41 23444 18297 2 851.488241 426.7525 Sterol carrier protein 2 OS=Homo sapiens OX=9606 GN=SCP2 PE=1 SV=2 8.75 3555.2 - 200468 - - - -2.6824 - 1.469 0.223 - 86.7 1 2 0 -0.0023 8 0 0 0 3.44E+06 2.43E+06 - - - 1.8472 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18299.18299.2 0.0107 22-Jul R.LVPVSFEDPEFK.S tr|F5GXE4|F5GXE4_HUMAN 1 1405.7129 6.9 23446 18299 2 1405.71607 703.8637 Arginyl-tRNA--protein transferase 1 OS=Homo sapiens OX=9606 GN=ATE1 PE=1 SV=1 4.14 3555.5 - 141170 - - - 2.2316 - 1.465 0.42 - 57.6 1 2 0 0.0031 12 0 0 0 1.83E+06 2.65E+05 - - - 3.1469 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18305.18305.2 0.000571 16-Sep K.GIFLGDQWR[166.11].D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1100.5642 2.64 23450 18305 2 1100.566316 551.2894 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3556.3 - 4.44E+06 - - - 1.8781 - 1.768 0.478 - 298.9 1 2 0 0.0021 9 0 0 0 8.83E+07 3.34E+07 - - - 4.2195 0.9658 230117_WJC_METTL3_WT_vs_EV_F03.18307.18307.2 0.43 16-Sep R.FLSGLELVK.Q "sp|Q96S44|PRPK_HUMAN,tr|Q5JZ02|Q5JZ02_HUMAN" 2 1004.5906 0.57 23452 18307 2 1004.594689 503.3026 EKC\KEOPS complex subunit TP53RK OS=Homo sapiens OX=9606 GN=TP53RK PE=1 SV=2 6 3556.5 - 1.74E+06 - - - 4.0375 - 1.523 0.05 - 168 2 2 0 0.0041 9 0 0 0 1.55E+07 2.72E+07 - - - 0.4916 0.9846 230117_WJC_METTL3_WT_vs_EV_F03.18308.18308.2 1.98 12-Jul R.SILEYLR.V sp|Q8N1G4|LRC47_HUMAN 1 892.5018 1.64 23453 18308 2 892.502537 447.2582 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 5.72 3556.6 - 1.54E+06 - - - 0.8056 - 1.143 0.102 - 193.1 1 2 0 0.0007 7 0 0 0 1.81E+07 1.10E+07 - - - 0.2176 0.9795 230117_WJC_METTL3_WT_vs_EV_F03.18311.18311.2 0.484 12-Jun K.AFFSPFR.L sp|Q92626|PXDN_HUMAN 1 870.4388 0.99 23456 18311 2 870.441654 436.2267 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 9.79 3557 - 775965 - - - 3.2512 - 1.257 0.099 - 124.3 1 2 0 0.0028 7 0 0 0 4.61E+06 4.68E+06 - - - 0.4961 1 230117_WJC_METTL3_WT_vs_EV_F03.18314.18314.2 0.000222 16-Nov K.YMAEALLLR.A sp|O94826|TOM70_HUMAN 1 1078.5845 1.63 23459 18314 2 1078.590434 540.2995 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 6 3557.4 - 631402 - - - 5.4998 - 2.196 0.486 - 373.4 1 2 0 0.0059 9 0 0 0 5.25E+06 3.22E+06 - - - 4.9045 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.18315.18315.2 0.513 12-Aug R.YDLWNLK[136.11].Y sp|Q9ULW3|ABT1_HUMAN 1 958.5004 0.52 23460 18315 2 958.503847 480.2575 Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1 5.83 3557.5 - 621104 - - - 3.6296 - 1.522 0.266 - 192.2 1 2 0 0.0035 7 0 0 0 5.86E+06 1.13E+07 - - - 2.3355 1 230117_WJC_METTL3_WT_vs_EV_F03.18319.18319.2 4.46E-10 14/26 K.FYGPEGPYGVFAGR.D sp|O00264|PGRC1_HUMAN 1 1515.7147 1.46 23464 18319 2 1515.717867 758.8646 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3558.1 - 323151 - - - 2.1132 - 2.649 0.696 - 711.1 1 2 0 0.0032 14 0 0 0 3.58E+07 2.46E+07 - - - 6.6253 1 230117_WJC_METTL3_WT_vs_EV_F03.18320.18320.2 5.56E-09 13/26 K.FYGPEGPYGVFAGR[166.11].D sp|O00264|PGRC1_HUMAN 1 1525.7229 1.46 23465 18320 2 1525.728976 763.8687 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3558.2 - 230118 - - - 3.9601 - 2.219 0.621 - 540.2 1 2 0 0.006 14 0 0 0 3.58E+07 2.46E+07 - - - 5.626 0.9803 230117_WJC_METTL3_WT_vs_EV_F03.18322.18322.2 0.425 20-Oct K.GLLPTPDEFPR.F sp|Q9C0J8|WDR33_HUMAN 1 1240.6452 1.24 23467 18322 2 1240.649283 621.3299 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 4.37 3558.5 - 1.00E+06 - - - 3.3007 - 1.022 0.196 - 119.1 1 2 0 0.0041 11 0 0 0 3.12E+06 2.53E+06 - - - 0.5462 1 230117_WJC_METTL3_WT_vs_EV_F03.18327.18327.2 1.00E-06 13/22 K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 999 23471 18327 2 1382.681775 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3559 - 2.67E+06 - - - -0.9077 - 2.538 0.464 - 497.1 1 2 0 -0.0013 12 0 0 0 1.10E+07 0.00E+00 - - - 4.9183 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18328.18328.2 0.00355 16-Aug R.ILFLDPSGK[136.11].V sp|O95881|TXD12_HUMAN 1 996.5735 1.07 23472 18328 2 996.57455 499.294 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3559.1 - 1.12E+07 - - - 1.0205 - 1.694 0.383 - 179.2 1 2 0 0.001 9 0 0 0 4.50E+08 4.20E+08 - - - 3.3944 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18331.18331.2 0.00103 18-Oct K.IGSDVELLLR[166.11].T sp|Q5U5X0|LYRM7_HUMAN 1 1123.6476 2.24 23475 18331 2 1123.646554 562.8311 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 4.37 3559.2 - 1.29E+06 - - - -0.9701 - 2.419 0.413 - 219.8 1 2 0 -0.0011 10 0 0 0 2.97E+07 1.32E+07 - - - 4.5568 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.18333.18333.2 0.0108 14-Aug R.GFGFVQFK[136.11].N "sp|Q9NW13|RBM28_HUMAN,tr|C9JE21|C9JE21_HUMAN" 2 936.4949 0.73 23477 18333 2 936.496006 469.2547 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 8.75 3559.4 - 1.06E+06 - - - 1.1927 - 1.38 0.213 - 144.2 1 2 0 0.0011 8 0 0 0 1.42E+07 1.93E+07 - - - 1.5853 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18336.18336.2 0.00256 20-Aug R.ILMLGLDAAGK[136.11].T sp|P62330|ARF6_HUMAN 1 1108.6406 1.35 23480 18336 2 1108.64365 555.3276 ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2 5.84 3559.8 - 553058 - - - 2.7809 - 1.557 0.429 - 104.8 1 2 0 0.0031 11 0 0 0 4.15E+06 3.07E+06 - - - 3.4064 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.18338.18338.2 0.000397 20-Oct R.MLDMGFEPQIR[166.11].R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1345.6398 1.19 23482 18338 2 1345.638351 673.8272 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3560 - 420072 - - - -1.0753 - 1.942 0.471 - 361.9 1 2 0 -0.0014 11 0 0 0 7.63E+07 6.39E+07 - - - 4.3149 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18339.18339.2 0.0122 24-Jun R.LFLAGYDPTPTMR.D sp|O75436|VP26A_HUMAN 1 1480.7384 11.04 23483 18339 2 1480.740615 741.3765 Vacuolar protein sorting-associated protein 26A OS=Homo sapiens OX=9606 GN=VPS26A PE=1 SV=2 5.84 3560.1 - 201375 - - - 1.4716 - 1.346 0.418 - 103.3 1 2 0 0.0022 13 0 0 0 7.17E+05 6.50E+04 - - - 2.8903 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18346.18346.2 0.0128 16-Sep K.LEVDIPLVK.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1024.6168 2.38 23488 18346 2 1024.619032 513.3157 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3560.9 - 3.67E+06 - - - 2.1315 - 1.826 0.466 - 228.1 1 2 0 0.0022 9 0 0 0 8.97E+07 3.77E+07 - - - 4.2242 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18347.18347.2 0.000354 16-Oct K.LEVDIPLVK[136.11].S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1032.631 2.38 23489 18347 2 1032.632637 517.3228 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3561 - 2.22E+06 - - - 1.5388 - 2.04 0.468 - 277.4 1 2 0 0.0016 9 0 0 0 8.97E+07 3.77E+07 - - - 4.5598 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.18349.18349.2 0.00533 14-Sep R.EMVLEIIR[166.11].E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1011.5662 1.42 23491 18349 2 1011.568791 506.7904 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3561.1 - 1.78E+06 - - - 2.5386 - 1.906 0.22 - 419.2 1 2 0 0.0026 8 0 0 0 2.29E+08 1.61E+08 - - - 2.6104 1 230117_WJC_METTL3_WT_vs_EV_F03.18350.18350.2 1.22E-05 13/20 R.MLDMGFEPQIR.R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1335.6315 1.19 23492 18350 2 1335.633341 668.823 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3561.3 - 1.17E+06 - - - 1.3574 - 2.275 0.593 - 636.4 1 2 0 0.0018 11 0 0 0 7.63E+07 6.39E+07 - - - 5.644 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.18352.18352.2 0.0948 16-Aug K.ILLITEDLK.N sp|Q08752|PPID_HUMAN 1 1056.6431 2.85 23494 18352 2 1056.645409 529.3288 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 4.37 3561.4 - 883939 - - - 2.2202 - 1.747 0.237 - 175.5 1 2 0 0.0023 9 0 0 0 1.78E+07 6.22E+06 - - - 2.4048 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.18354.18354.2 0.000395 20-Sep R.LPPEFSPVIIK[136.11].E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1246.7417 0.35 23496 18354 2 1246.746205 624.3781 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6 3561.7 - 639876 - - - 3.6447 - 1.489 0.322 - 179.6 1 2 0 0.0045 11 0 0 0 3.09E+06 8.83E+06 - - - 2.4948 0.9955 230117_WJC_METTL3_WT_vs_EV_F03.18356.18356.2 0.367 18-Jul R.VIALGLPVPR[166.11].Y sp|A3KMH1|VWA8_HUMAN 1 1043.6731 1.31 23498 18356 2 1043.674455 522.8438 von Willebrand factor A domain-containing protein 8 OS=Homo sapiens OX=9606 GN=VWA8 PE=1 SV=2 9.72 3562 - 267695 - - - 1.3261 - 1.439 0.153 - 89.9 2 2 0 0.0014 10 0 0 0 1.63E+06 1.24E+06 - - - 1.052 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.18361.18361.2 0.499 14-Sep R.EMVLEIIR.E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1001.558 1.4 23501 18361 2 1001.559431 501.7863 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3562.6 - 9.64E+06 - - - 1.4757 - 1.901 0.168 - 393.2 1 2 0 0.0015 8 0 0 0 2.26E+08 1.61E+08 - - - 2.2188 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.18363.18363.2 0.106 14-Sep K.VALLLLEK.E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 897.5899 1.36 23503 18363 2 897.591888 449.8022 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3562.8 - 2.62E+06 - - - 2.2092 - 1.776 0.228 - 307 1 2 0 0.002 8 0 0 0 1.36E+07 9.99E+06 - - - 2.4566 0.9283 230117_WJC_METTL3_WT_vs_EV_F03.18365.18365.2 1.95 14-Jun R.GFGFVQFK.N "sp|Q9NW13|RBM28_HUMAN,tr|C9JE21|C9JE21_HUMAN" 2 928.4807 0.73 23505 18365 2 928.483705 465.2476 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 8.75 3563 - 2.07E+06 - - - 3.2483 - 1.176 0.033 - 90.9 2 2 0 0.003 8 0 0 0 1.41E+07 1.94E+07 - - - -0.3617 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18367.18367.2 0.000401 22-Nov K.GLTPSQIGVILR[166.11].D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1262.7586 0.88 23507 18367 2 1262.761105 632.3866 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3563.2 - 1.15E+06 - - - 1.9901 - 2.316 0.347 - 506.8 1 2 0 0.0025 12 0 0 0 3.59E+07 4.10E+07 - - - 3.8129 0.9957 230117_WJC_METTL3_WT_vs_EV_F03.18371.18371.2 0.864 16-Jun R.LLYGMALVR[166.11].F "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3R6|A0A7I2V3R6_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V4V0|A0A7I2V4V0_HUMAN,tr|A0A7I2V5R7|A0A7I2V5R7_HUMAN,tr|A0A7I2V653|A0A7I2V653_HUMAN,tr|A0A7I2YQI7|A0A7I2YQI7_HUMAN" 7 1044.6029 1.29 23511 18371 2 1044.60369 523.3087 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 8.75 3563.7 - 436556 - - - 0.7161 - 1.317 0.178 - 76.2 1 2 0 0.0007 9 0 0 0 7.95E+06 6.17E+06 - - - 1.1521 0.9948 230117_WJC_METTL3_WT_vs_EV_F03.18373.18373.2 0.00723 20-Aug R.YFGPNLLNTVK[136.11].Q "sp|P62487|RPB7_HUMAN,tr|E9PIU7|E9PIU7_HUMAN,tr|E9PKH3|E9PKH3_HUMAN,tr|H0YEE4|H0YEE4_HUMAN" 4 1272.6958 0.85 23513 18373 2 1272.701793 637.3552 DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1 8.59 3564 - 311667 - - - 4.7301 - 1.52 0.316 - 161.1 1 2 0 0.006 11 0 0 0 2.42E+06 2.86E+06 - - - 2.5058 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18377.18377.2 1.27E-05 22-Nov K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 0.88 23515 18377 2 1252.752312 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3564.4 - 1.25E+06 - - - 1.5885 - 2.357 0.342 - 517.9 1 2 0 0.002 12 0 0 0 3.59E+07 4.10E+07 - - - 3.8223 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.18378.18378.2 0.282 12-Jun R.EIFITFR.V sp|Q96EY1|DNJA3_HUMAN 1 924.5069 1.84 23516 18378 2 924.508302 463.2607 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.1 3564.5 - 973355 - - - 1.5132 - 1.341 0.212 - 119.7 1 2 0 0.0014 7 0 0 0 1.98E+07 1.08E+07 - - - 1.5361 1 230117_WJC_METTL3_WT_vs_EV_F03.18380.18380.2 1.47E-06 16-Sep K.LYMVLITTK.N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 3 1080.6253 1.52 23518 18380 2 1080.626831 541.3199 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 8.59 3564.6 - 1.13E+06 - - - 1.4131 - 1.952 0.558 - 274.1 1 2 0 0.0015 9 0 0 0 1.11E+07 7.31E+06 - - - 5.0969 0.997 230117_WJC_METTL3_WT_vs_EV_F03.18389.18389.2 0.00587 14-Aug K.VALLLLEK[136.11].E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 905.6041 1.36 23526 18389 2 905.605058 453.8093 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3565.8 - 460901 - - - 1.0523 - 1.773 0.084 - 210.6 1 2 0 0.001 8 0 0 0 1.37E+07 1.01E+07 - - - 1.3883 1 230117_WJC_METTL3_WT_vs_EV_F03.18391.18391.2 1.67E-05 18-Oct K.FYALDPSFPR.M sp|Q08J23|NSUN2_HUMAN 1 1211.5975 1.47 23527 18391 2 1211.593551 606.806 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3566 - 816554 - - - -3.2668 - 2.04 0.559 - 335.4 1 2 0 -0.004 10 0 0 0 1.45E+07 9.82E+06 - - - 5.1586 0.9794 230117_WJC_METTL3_WT_vs_EV_F03.18394.18394.2 0.215 12-Jun R.EIFITFR[166.11].V sp|Q96EY1|DNJA3_HUMAN 1 934.5152 1.84 23530 18394 2 934.514299 468.2649 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.1 3566.3 - 1.13E+06 - - - -0.9352 - 1.345 0.088 - 138.6 1 2 0 -0.0009 7 0 0 0 1.98E+07 1.08E+07 - - - 0.6298 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18395.18395.2 0.000991 14-Oct K.NGLDVLFK.V "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 904.5018 1.08 23531 18395 2 904.50317 453.2582 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 5.84 3566.4 - 486023 - - - 1.4947 - 1.58 0.414 - 308.8 1 2 0 0.0014 8 0 0 0 5.16E+06 4.79E+06 - - - 3.478 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18396.18396.2 0.00738 18-Sep K.FASVLPEYLK.V "sp|Q86XI2|CNDG2_HUMAN,tr|H0Y6U5|H0Y6U5_HUMAN" 2 1165.6383 2.28 23532 18396 2 1165.63948 583.8264 Condensin-2 complex subunit G2 OS=Homo sapiens OX=9606 GN=NCAPG2 PE=1 SV=1 6 3566.5 - 398566 - - - 1.0029 - 1.812 0.336 - 187.3 1 2 0 0.0012 10 0 0 0 6.14E+06 2.69E+06 - - - 3.1816 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18397.18397.2 0.00148 18-Oct K.ALQEFDLALR.G "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1174.6346 0.61 23533 18397 2 1174.635557 588.3246 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 4.37 3566.6 - 351213 - - - 0.7951 - 1.984 0.369 - 338.1 1 2 0 0.0009 10 0 0 0 6.25E+06 1.02E+07 - - - 3.6785 1 230117_WJC_METTL3_WT_vs_EV_F03.18398.18398.2 3.05E-06 22-Dec K.AFAVGVQQVLLK.V sp|O95373|IPO7_HUMAN 1 1271.7602 1.89 23534 18398 2 1271.766565 636.8874 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 8.8 3566.7 - 350838 - - - 5.0379 - 2.696 0.633 - 525.6 1 2 0 0.0064 12 0 0 0 1.15E+07 6.06E+06 - - - 6.3238 0.9958 230117_WJC_METTL3_WT_vs_EV_F03.18399.18399.2 0.566 12-Jun R.DLFALAR[166.11].K sp|Q9Y4W6|AFG32_HUMAN 1 814.4577 1.42 23535 18399 2 814.459124 408.2361 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.84 3566.9 - 337415 - - - 1.8 - 1.202 0.205 - 170.2 1 2 0 0.0015 7 0 0 0 7.11E+06 5.00E+06 - - - 1.1376 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18406.18406.2 0.0475 16-Nov R.LYSVSYLLK[136.11].D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1092.631 0.73 23540 18406 2 1092.63341 547.3228 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.5 3567.7 - 3.57E+06 - - - 2.1618 - 2.118 0.452 - 334.7 1 2 0 0.0024 9 0 0 0 2.44E+07 3.33E+07 - - - 4.5499 0.9949 230117_WJC_METTL3_WT_vs_EV_F03.18407.18407.2 1.14 12-Jul R.DLFALAR.K sp|Q9Y4W6|AFG32_HUMAN 1 804.4494 1.42 23541 18407 2 804.451113 403.232 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.84 3567.8 - 640823 - - - 2.1443 - 1.261 0.177 - 213 1 2 0 0.0017 7 0 0 0 7.11E+06 5.02E+06 - - - 1.0826 1 230117_WJC_METTL3_WT_vs_EV_F03.18408.18408.2 7.89E-06 22-Dec R.MGLAISLVATEK[136.11].E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 1239.6988 1.44 23542 18408 2 1239.698251 620.8567 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.75 3567.9 - 1.94E+06 - - - -0.4509 - 2.54 0.512 - 414.3 1 2 0 -0.0006 12 0 0 0 2.23E+07 1.55E+07 - - - 5.2751 1 230117_WJC_METTL3_WT_vs_EV_F03.18410.18410.2 4.93E-07 22-Dec K.AFAVGVQQVLLK[136.11].V sp|O95373|IPO7_HUMAN 1 1279.7744 1.89 23544 18410 2 1279.776946 640.8945 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 8.8 3568.2 - 899175 - - - 2.0222 - 2.628 0.573 - 453.2 1 2 0 0.0026 12 0 0 0 1.15E+07 6.06E+06 - - - 5.8147 0.9467 230117_WJC_METTL3_WT_vs_EV_F03.18411.18411.2 0.268 14-Oct V.ILSILLSK[136.11].A "sp|Q6UXB4|CLC4G_HUMAN,sp|Q02040|AK17A_HUMAN,tr|A0A7I2V4C7|A0A7I2V4C7_HUMAN,tr|M0R277|M0R277_HUMAN,tr|A0A7I2V4U5|A0A7I2V4U5_HUMAN" 5 893.6041 1.14 23545 18411 2 893.60557 447.8093 C-type lectin domain family 4 member G OS=Homo sapiens OX=9606 GN=CLEC4G PE=1 SV=1 8.75 3568.3 - 857718 - - - 1.6394 - 1.798 0.269 - 242.5 1 1 0 0.0015 8 0 0 0 6.58E+06 5.76E+06 - - - 2.7968 1 230117_WJC_METTL3_WT_vs_EV_F03.18413.18413.2 0.000771 18-Sep K.VFLSGMPELR.L "sp|Q9Y6Q5|AP1M2_HUMAN,sp|Q9BXS5|AP1M1_HUMAN,tr|E7ENJ6|E7ENJ6_HUMAN,tr|K7EJL1|K7EJL1_HUMAN,tr|K7EJJ1|K7EJJ1_HUMAN,tr|K7EMG5|K7EMG5_HUMAN,tr|K7EPR4|K7EPR4_HUMAN" 7 1147.606 1.08 23547 18413 2 1147.60794 574.8103 AP-1 complex subunit mu-2 OS=Homo sapiens OX=9606 GN=AP1M2 PE=1 SV=4 5.97 3568.6 - 509992 - - - 1.721 - 1.932 0.507 - 265.1 1 2 0 0.002 10 0 0 0 4.20E+06 3.89E+06 - - - 4.6233 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18414.18414.2 3.38 18-Oct R.LLDEQFAVLR.G sp|O75146|HIP1R_HUMAN 1 1202.6659 0.42 23548 18414 2 1202.669281 602.3402 Huntingtin-interacting protein 1-related protein OS=Homo sapiens OX=9606 GN=HIP1R PE=1 SV=2 4.37 3568.7 - 341493 - - - 2.7921 - 2.227 0.357 - 222.3 1 2 0 0.0034 10 0 0 0 2.15E+06 5.12E+06 - - - 3.9116 1 230117_WJC_METTL3_WT_vs_EV_F03.18421.18421.2 0.00071 13/22 R.MGLAISLVATEK.E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 1231.6846 1.44 23553 18421 2 1231.689887 616.8496 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.75 3569.5 - 434100 - - - 4.2844 - 2.558 0.499 - 562.5 1 2 0 0.0053 12 0 0 0 2.23E+07 1.55E+07 - - - 5.1962 0.994 230117_WJC_METTL3_WT_vs_EV_F03.18426.18426.2 0.509 16-Aug R.LLYGMALVR.F "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3R6|A0A7I2V3R6_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V4V0|A0A7I2V4V0_HUMAN,tr|A0A7I2V5R7|A0A7I2V5R7_HUMAN,tr|A0A7I2V653|A0A7I2V653_HUMAN,tr|A0A7I2YQI7|A0A7I2YQI7_HUMAN" 7 1034.5947 1.29 23558 18426 2 1034.596672 518.3046 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 8.75 3570.1 - 382023 - - - 1.9322 - 1.324 0.141 - 136.2 1 2 0 0.002 9 0 0 0 7.95E+06 6.17E+06 - - - 0.8938 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.18428.18428.2 0.325 18-Nov K.ALQEFDLALR[166.11].G "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1184.6429 0.76 23560 18428 2 1184.646783 593.3287 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 4.37 3570.3 - 263696 - - - 3.2837 - 1.861 0.259 - 434.6 1 2 0 0.0039 10 0 0 0 5.93E+06 7.81E+06 - - - 2.6865 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.18429.18429.2 0.112 14-Sep R.LYLLQGIR.N "sp|Q9Y5A7|NUB1_HUMAN,tr|H3BM74|H3BM74_HUMAN,tr|H3BM14|H3BM14_HUMAN" 3 974.5913 1.86 23561 18429 2 974.593996 488.3029 NEDD8 ultimate buster 1 OS=Homo sapiens OX=9606 GN=NUB1 PE=1 SV=2 8.75 3570.4 - 245052 - - - 2.7642 - 1.733 0.328 - 273.8 1 2 0 0.0027 8 0 0 0 4.23E+06 2.27E+06 - - - 3.1211 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.18430.18430.2 0.266 18-Jul K.FYALDPSFPR[166.11].M sp|Q08J23|NSUN2_HUMAN 1 1221.6058 1.48 23562 18430 2 1221.609241 611.8102 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3570.6 - 242533 - - - 2.834 - 1.466 0.21 - 164.4 1 2 0 0.0035 10 0 0 0 1.64E+07 1.11E+07 - - - 1.6588 1 230117_WJC_METTL3_WT_vs_EV_F03.18436.18436.2 2.38E-07 20-Oct K.LVNIYDSMPLR.Y sp|Q9UBQ6|EXTL2_HUMAN 1 1319.6908 0.58 23568 18436 2 1319.693936 660.8527 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 5.84 3571.4 - 82686.9 - - - 2.4081 - 2.557 0.537 - 418.3 1 2 0 0.0032 11 0 0 0 8.15E+05 1.39E+06 - - - 5.5461 1 230117_WJC_METTL3_WT_vs_EV_F03.18444.18444.2 0.00695 20-Dec F.IGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1068.6543 6.37 23574 18444 2 1068.656822 535.3344 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 3572.4 - 736911 - - - 2.3637 - 2.601 0.404 - 429.6 1 1 0 0.0025 11 0 0 0 1.78E+08 2.80E+07 - - - 4.6101 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.18446.18446.2 0.108 12-Jul R.NYLSIFR.K sp|P07384|CAN1_HUMAN 1 911.4865 4.44 23576 18446 2 911.487399 456.7505 Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1 8.75 3572.6 - 266334 - - - 0.9841 - 1.411 0.187 - 208.8 1 2 0 0.0009 7 0 0 0 3.70E+06 8.34E+05 - - - 1.5128 1 230117_WJC_METTL3_WT_vs_EV_F03.18449.18449.2 2.01E-06 30-Oct K.IFVGGLSANTVVEDVK.Q "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|J3KTC1|J3KTC1_HUMAN" 5 1646.8879 -1 23579 18449 2 1646.889486 824.4512 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.37 3573 - 0 - - - 0.9406 - 2.231 0.511 - 161.6 1 2 0 0.0015 16 0 0 0 0.00E+00 0.00E+00 - - - 4.7876 0.8691 230117_WJC_METTL3_WT_vs_EV_F03.18451.18451.2 2.77 14-May K.SIGDIFLK[136.11].Y "sp|Q9H8V3|ECT2_HUMAN,tr|H7C3G1|H7C3G1_HUMAN" 2 899.5208 0.91 23580 18451 2 899.522684 450.7677 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 5.55 3573.2 - 496721 - - - 2.1289 - 0.803 0.093 - 59.2 3 2 0 0.0019 8 0 0 0 9.34E+06 1.03E+07 - - - -1.1475 0.997 230117_WJC_METTL3_WT_vs_EV_F03.18456.18456.2 1.46E-05 18-Sep R.VLLMELEEAR.G sp|P12270|TPR_HUMAN 1 1201.6377 1.44 23584 18456 2 1201.644232 601.8261 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3573.8 - 1.46E+06 - - - 5.4692 - 2.295 0.36 - 338.2 1 2 0 0.0066 10 0 0 0 2.51E+07 1.74E+07 - - - 4.0167 0.9849 230117_WJC_METTL3_WT_vs_EV_F03.18457.18457.2 0.00205 14-Aug K.SYYLGLLR.S "sp|Q96LB3|IFT74_HUMAN,tr|E5RJK3|E5RJK3_HUMAN,tr|E5RGX6|E5RGX6_HUMAN,tr|A0A3B3IT46|A0A3B3IT46_HUMAN,tr|E5RIF0|E5RIF0_HUMAN,tr|E5RH29|E5RH29_HUMAN" 6 983.544 2.91 23585 18457 2 983.551639 492.7793 Intraflagellar transport protein 74 homolog OS=Homo sapiens OX=9606 GN=IFT74 PE=1 SV=1 8.31 3573.9 - 945918 - - - 7.7495 - 1.661 0.407 - 278.1 1 2 0 0.0076 8 0 0 0 7.05E+06 2.42E+06 - - - 3.5751 1 230117_WJC_METTL3_WT_vs_EV_F03.18459.18459.2 9.29E-05 18-Dec K.TLVQILTEPR.N sp|O76031|CLPX_HUMAN 1 1168.6816 2.24 23587 18459 2 1168.688581 585.3481 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3574.2 - 510368 - - - 5.9965 - 2.58 0.435 - 660.8 1 2 0 0.007 10 0 0 0 1.69E+07 7.53E+06 - - - 4.8973 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.18461.18461.2 0.419 12-Sep K.C[160.03]ALDFFR[166.11].Q sp|P51970|NDUA8_HUMAN 1 937.4355 1.5 23589 18461 2 937.44062 469.725 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3574.4 - 400770 - - - 5.4158 - 1.718 0.33 - 298.9 1 2 0 0.0051 7 0 0 0 1.86E+07 1.24E+07 - - - 3.1915 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.18465.18465.2 0.0276 16-Sep K.LQDPFSLYR.C sp|P21912|SDHB_HUMAN 1 1137.5819 3.96 23593 18465 2 1137.586284 569.7982 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.84 3575 - 326454 - - - 3.8898 - 1.921 0.263 - 163.5 1 2 0 0.0044 9 0 0 0 3.95E+07 9.98E+06 - - - 2.8708 0.9733 230117_WJC_METTL3_WT_vs_EV_F03.18468.18468.2 0.000658 24-Sep K.LFPDTPLALDANK[136.11].K sp|Q12906|ILF3_HUMAN 1 1421.7646 0.85 23596 18468 2 1421.777252 711.8896 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3575.4 - 142814 - - - 8.9122 - 1.72 0.378 - 225.1 1 2 0 0.0127 13 0 0 0 9.00E+06 1.06E+07 - - - 3.2208 0.9452 230117_WJC_METTL3_WT_vs_EV_F03.18474.18474.2 0.00454 13/20 F.IGAIAIGDLVK[136.11].S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1076.6685 6.37 23600 18474 2 1076.671215 539.3415 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 3576.2 - 2.45E+06 - - - 2.5254 - 2.398 0.238 - 367.8 1 1 0 0.0027 11 0 0 0 1.78E+08 2.80E+07 - - - 3.1641 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18478.18478.2 0.00598 12-Sep K.C[160.03]ALDFFR.Q sp|P51970|NDUA8_HUMAN 1 927.4273 1.5 23604 18478 2 927.429542 464.7209 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3576.5 - 637166 - - - 2.4466 - 1.759 0.352 - 400.6 1 2 0 0.0023 7 0 0 0 1.86E+07 1.24E+07 - - - 3.4296 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18484.18484.2 0.00159 18-Oct K.TLVQILTEPR[166.11].N sp|O76031|CLPX_HUMAN 1 1178.6898 2.28 23610 18484 2 1178.692552 590.3522 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3577.2 - 194736 - - - 2.2983 - 2.258 0.418 - 360.1 1 2 0 0.0027 10 0 0 0 1.67E+07 7.32E+06 - - - 4.401 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.18488.18488.2 0.00109 16-Sep K.LLQDFFNGR.D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1108.5665 13.75 23612 18488 2 1108.570986 555.2905 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3577.8 - 2.49E+07 - - - 4.0079 - 1.967 0.462 - 323.5 1 2 0 0.0044 9 0 0 0 3.18E+08 2.31E+07 - - - 4.4091 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.18489.18489.2 0.00221 18-Aug K.FLALYLHGAA.- "sp|Q9BZE1|RM37_HUMAN,tr|A6NHR2|A6NHR2_HUMAN" 2 1074.5862 - 23613 18489 2 1074.590293 538.3004 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 6.74 3577.8 - 2.53E+06 - - - 3.794 - 1.621 0.398 - 161.2 1 2 0 0.0041 10 0 0 0 - - - - - 3.3277 0.9958 230117_WJC_METTL3_WT_vs_EV_F03.18494.18494.2 0.189 12-Jun R.TIFSYFK.G sp|Q9UJV9|DDX41_HUMAN 1 904.4695 1.13 23618 18494 2 904.470118 453.242 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 8.26 3578.4 - 402119 - - - 0.733 - 1.202 0.209 - 110.8 1 2 0 0.0007 7 0 0 0 3.17E+07 2.80E+07 - - - 1.1674 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18496.18496.2 0.00253 22-Sep K.LLHSDLAPTLLE.- sp|Q6ZQX7|LIAT1_HUMAN 1 1320.7289 - 23620 18496 2 1320.730612 661.3717 Protein LIAT1 OS=Homo sapiens OX=9606 GN=LIAT1 PE=1 SV=2 4.71 3578.7 - 286921 - - - 1.2834 - 1.815 0.331 - 264.5 1 2 0 0.0017 12 0 0 0 - - - - - 3.0536 1 230117_WJC_METTL3_WT_vs_EV_F03.18497.18497.2 1.35E-06 18-Dec K.LGMNLMNELK.Q "sp|Q16890|TPD53_HUMAN,tr|E9PNK6|E9PNK6_HUMAN,tr|E9PNQ9|E9PNQ9_HUMAN,tr|E9PPQ1|E9PPQ1_HUMAN,tr|J3KNE7|J3KNE7_HUMAN" 5 1161.5886 2.5 23621 18497 2 1161.588829 581.8016 Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1 6 3578.8 - 274060 - - - 0.1963 - 2.447 0.443 - 356.8 1 2 0 0.0002 10 0 0 0 5.71E+06 2.28E+06 - - - 4.8108 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.18500.18500.2 0.0749 16-Nov K.LALFQAIGK.E "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 959.5804 1.51 23624 18500 2 959.579955 480.7975 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 8.75 3579.2 - 224764 - - - -0.4669 - 2.12 0.314 - 276.4 1 2 0 -0.0004 9 0 0 0 4.12E+06 2.73E+06 - - - 3.534 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18501.18501.2 3.53E-05 24-Nov K.LFPDTPLALDANK.K sp|Q12906|ILF3_HUMAN 1 1413.7504 0.85 23625 18501 2 1413.753379 707.8825 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3579.3 - 223715 - - - 2.1206 - 1.789 0.483 - 242.3 1 2 0 0.003 13 0 0 0 9.00E+06 1.06E+07 - - - 4.1003 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.18505.18505.2 0.000696 20-Sep R.LPPEFSPVIIK.E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1238.7275 1 23629 18505 2 1238.731912 620.371 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6 3579.8 - 164517 - - - 3.5932 - 1.807 0.343 - 166.9 1 2 0 0.0045 11 0 0 0 2.95E+06 2.96E+06 - - - 3.1736 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.18512.18512.2 0.035 14-Jul R.LLLEEIYR.G "sp|Q9Y2P8|RCL1_HUMAN,tr|Q5VZU2|Q5VZU2_HUMAN,tr|Q5VZU3|Q5VZU3_HUMAN" 3 1047.5964 0.64 23634 18512 2 1047.598601 524.8055 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 4.53 3580.5 - 711875 - - - 2.0561 - 1.587 0.234 - 172 1 2 0 0.0022 8 0 0 0 1.65E+07 2.57E+07 - - - 2.1616 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.18513.18513.2 0.228 18-Aug R.LGLLGLPAPK.N sp|Q99459|CDC5L_HUMAN 1 977.6274 1.09 23635 18513 2 977.628446 489.821 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3580.6 - 680494 - - - 1.118 - 1.888 0.131 - 150.7 1 2 0 0.0011 10 0 0 0 8.24E+07 7.56E+07 - - - 1.7821 0.9784 230117_WJC_METTL3_WT_vs_EV_F03.18514.18514.2 0.368 12-Jun K.EVILPIK.V sp|Q4G0P3|HYDIN_HUMAN 1 810.5215 1.43 23636 18514 2 810.522066 406.268 Hydrocephalus-inducing protein homolog OS=Homo sapiens OX=9606 GN=HYDIN PE=1 SV=3 6.1 3580.6 - 649795 - - - 0.7094 - 1.313 0.014 - 154.8 1 2 0 0.0006 7 0 0 0 1.68E+07 1.18E+07 - - - 0.0071 0.9639 230117_WJC_METTL3_WT_vs_EV_F03.18516.18516.2 1.24 12-Jul K.DLLLPIK[136.11].T "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 3 818.5357 1.42 23638 18516 2 818.535746 410.2751 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 5.84 3580.8 - 457742 - - - 0.0672 - 1.28 0.002 - 211 1 2 0 0.0001 7 0 0 0 1.67E+07 1.18E+07 - - - -0.1621 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.18526.18526.2 0.00605 18-Oct R.LGLLGLPAPK[136.11].N sp|Q99459|CDC5L_HUMAN 1 985.6416 1.13 23646 18526 2 985.644232 493.8281 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3581.7 - 2.90E+06 - - - 2.718 - 1.996 0.184 - 230.2 1 2 0 0.0027 10 0 0 0 8.59E+07 7.58E+07 - - - 2.3284 1 230117_WJC_METTL3_WT_vs_EV_F03.18529.18529.2 3.78E-08 22/28 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 1.47 23649 18529 2 1458.763509 730.386 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3582 - 787479 - - - 4.1487 - 3.978 0.621 - 1725.5 1 2 0 0.0061 15 0 0 0 1.35E+08 9.18E+07 - - - 7.0205 1 230117_WJC_METTL3_WT_vs_EV_F03.18530.18530.2 6.72E-07 18/28 R.LPAAGVGDMVMATVK[136.11].K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1466.7717 1.47 23650 18530 2 1466.775995 734.3931 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3582.2 - 588136 - - - 2.9575 - 3.725 0.601 - 1281.1 1 2 0 0.0043 15 0 0 0 1.35E+08 9.18E+07 - - - 6.7118 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.18535.18535.2 0.00421 20-Aug K.LFVINEVC[160.03]EMK.N sp|Q8TDN6|BRX1_HUMAN 1 1380.6781 2.53 23655 18535 2 1380.674788 691.3463 Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2 4.53 3582.8 - 211912 - - - -2.4314 - 1.529 0.351 - 119.9 1 2 0 -0.0034 11 0 0 0 2.33E+06 9.20E+05 - - - 2.7811 0.9915 230117_WJC_METTL3_WT_vs_EV_F03.18536.18536.2 0.0112 20-Jul K.LFVINEVC[160.03]EMK[136.11].N sp|Q8TDN6|BRX1_HUMAN 1 1388.6923 -1 23656 18536 2 1388.699914 695.3534 Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2 4.53 3582.9 - 198175 - - - 5.4505 - 1.426 0.339 - 111.5 1 2 0 0.0076 11 0 0 0 0.00E+00 0.00E+00 - - - 2.5025 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.18540.18540.2 0.0136 16-Sep K.LLQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1118.5748 13.75 23659 18540 2 1118.578721 560.2947 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3583.4 - 294504 - - - 3.4937 - 1.779 0.367 - 236.3 1 2 0 0.0039 9 0 0 0 3.18E+08 2.31E+07 - - - 3.417 0.9889 230117_WJC_METTL3_WT_vs_EV_F03.18541.18541.2 0.252 14-Sep R.WEVIDVVR[166.11].T "sp|Q8IZX4|TAF1L_HUMAN,sp|P21675|TAF1_HUMAN,tr|A0A804HK58|A0A804HK58_HUMAN,tr|A0A804HIY8|A0A804HIY8_HUMAN,tr|A0A804HIC2|A0A804HIC2_HUMAN" 5 1024.5581 0.64 23660 18541 2 1024.560772 513.2863 Transcription initiation factor TFIID subunit 1-like OS=Homo sapiens OX=9606 GN=TAF1L PE=1 SV=1 4.37 3583.5 - 258440 - - - 2.607 - 1.295 0.114 - 169.3 1 2 0 0.0027 8 0 0 0 6.71E+06 1.04E+07 - - - 0.6618 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18542.18542.2 0.00148 20-Nov R.LYEAYLPETFR.R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1400.6976 2.27 23661 18542 2 1400.700943 701.3561 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3583.6 - 610865 - - - 2.3745 - 2.223 0.395 - 393.1 1 2 0 0.0033 11 0 0 0 3.69E+07 1.62E+07 - - - 4.1185 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.18543.18543.2 0.0119 12-Jun R.VWSDFLR.V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 921.4709 2.5 23662 18543 2 921.472251 461.7427 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.81 3583.7 - 586999 - - - 1.5182 - 1.359 0.299 - 175.5 1 2 0 0.0014 7 0 0 0 1.37E+07 5.46E+06 - - - 2.2209 0.999 230117_WJC_METTL3_WT_vs_EV_F03.18545.18545.2 0.00986 12-Jul R.VWSDFLR[166.11].V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 931.4791 2.56 23664 18545 2 931.4806 466.7468 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.81 3584 - 253788 - - - 1.5867 - 1.438 0.293 - 196.6 1 2 0 0.0015 7 0 0 0 1.36E+07 5.30E+06 - - - 2.3556 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18547.18547.2 0.000747 20-Sep R.IFVFEPPPGVK[136.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 1236.6998 2.21 23666 18547 2 1236.703314 619.3572 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3584.3 - 104328 - - - 2.8447 - 1.831 0.398 - 201.8 1 2 0 0.0035 11 0 0 0 4.71E+06 2.13E+06 - - - 3.6158 1 230117_WJC_METTL3_WT_vs_EV_F03.18548.18548.2 0.000187 20-Dec K.LALDMEIATYR.K "sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|Q14CN4|K2C72_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 4 1294.6591 65.92 23667 18548 2 1294.661822 648.3368 "Keratin, type II cytoskeletal 74 OS=Homo sapiens OX=9606 GN=KRT74 PE=1 SV=2" 4.37 3584.4 - 93877.3 - - - 2.0847 - 2.649 0.451 - 675.5 1 2 0 0.0027 11 0 0 0 6.62E+06 1.00E+05 - - - 5.0066 0.9826 230117_WJC_METTL3_WT_vs_EV_F03.18552.18552.2 0.513 12-Jun R.LFLEFER.K "sp|O43663|PRC1_HUMAN,sp|Q96I25|SPF45_HUMAN,tr|H0YL53|H0YL53_HUMAN" 3 952.5018 2.12 23669 18552 2 952.506327 477.2582 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 3584.9 - 4.01E+06 - - - 4.7338 - 1.355 0.185 - 159.7 1 2 0 0.0045 7 0 0 0 2.71E+07 1.28E+07 - - - 1.3686 1 230117_WJC_METTL3_WT_vs_EV_F03.18553.18553.2 0.00329 22-Dec K.YILAATLDNTLK[136.11].L sp|P61964|WDR5_HUMAN 1 1342.7588 1.4 23670 18553 2 1342.762144 672.3867 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 5.83 3584.9 - 4.69E+06 - - - 2.5142 - 2.343 0.457 - 366.3 1 2 0 0.0034 12 0 0 0 2.96E+07 2.12E+07 - - - 4.6556 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18554.18554.3 1.38E-07 13/56 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 1.33 23671 18554 3 1458.762915 487.2598 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3585 - 4.18E+06 - - - 3.7415 - 2.64 0.352 - 253.5 1 2 0 0.0055 15 0 0 0 2.18E+07 1.64E+07 - - - 4.9961 0.996 230117_WJC_METTL3_WT_vs_EV_F03.18556.18556.2 0.00313 14-Aug K.YLELLGYR[166.11].K "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 7 1035.5629 1.46 23673 18556 2 1035.566308 518.7887 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6 3585.1 - 2.08E+06 - - - 3.3373 - 1.772 0.145 - 220.6 1 2 0 0.0035 8 0 0 0 1.13E+07 7.69E+06 - - - 1.8363 1 230117_WJC_METTL3_WT_vs_EV_F03.18557.18557.2 2.87E-05 20-Dec R.LYEAYLPETFR[166.11].R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1410.7059 2.27 23674 18557 2 1410.709708 706.3602 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3585.2 - 1.90E+06 - - - 2.7086 - 2.292 0.532 - 382.5 1 2 0 0.0038 11 0 0 0 3.69E+07 1.62E+07 - - - 5.2129 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18558.18558.2 0.00386 18-Nov K.MIIENFEALK[136.11].S "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1214.646 1.29 23675 18558 2 1214.650378 608.3303 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 4.53 3585.4 - 1.60E+06 - - - 3.5665 - 2.099 0.423 - 309.8 1 2 0 0.0043 10 0 0 0 1.12E+07 8.69E+06 - - - 4.2336 1 230117_WJC_METTL3_WT_vs_EV_F03.18559.18559.2 0.000131 22-Dec R.VPLSTVLLDPTR.S sp|Q9Y2I1|NISCH_HUMAN 1 1309.7606 2.18 23676 18559 2 1309.761833 655.8876 Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3 5.81 3585.5 - 571866 - - - 0.978 - 2.41 0.482 - 543 1 2 0 0.0013 12 0 0 0 2.40E+06 1.10E+06 - - - 4.9151 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.18565.18565.2 0.000461 20-Oct R.YLTPYDSLLGK.N "sp|O15417|TNC18_HUMAN,tr|H7C0N9|H7C0N9_HUMAN,tr|H9KVB4|H9KVB4_HUMAN" 3 1268.6653 -1 23682 18565 2 1268.663626 635.3399 Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3 5.83 3586.3 - 269610 - - - -1.284 - 1.582 0.3 - 344.3 1 2 0 -0.0016 11 0 0 0 0.00E+00 0.00E+00 - - - 2.4972 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.18566.18566.2 0.0305 22-Jun K.QLDMIQQFIQDR.S sp|Q96M95|CCD42_HUMAN 1 1533.761 -1 23683 18566 2 1533.766096 767.8878 Coiled-coil domain-containing protein 42 OS=Homo sapiens OX=9606 GN=CCDC42 PE=1 SV=2 4.21 3586.4 - 136222 - - - 3.3467 - 1.382 0.347 - 96.3 1 2 0 0.0051 12 0 0 0 0.00E+00 0.00E+00 - - - 2.4536 1 230117_WJC_METTL3_WT_vs_EV_F03.18569.18569.2 2.06E-07 16/30 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 23.81 23684 18569 2 1686.897969 844.4543 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3586.8 - 1.28E+06 - - - 2.3025 - 3.2 0.574 - 682.4 1 2 0 0.0039 16 0 0 0 6.39E+07 2.68E+06 - - - 6.139 1 230117_WJC_METTL3_WT_vs_EV_F03.18571.18571.2 3.53E-07 22-Nov K.FGEAIGMGFPVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1259.6464 0.96 23686 18571 2 1259.650011 630.8305 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3587 - 855359 - - - 2.8826 - 2.427 0.531 - 371.2 1 2 0 0.0036 12 0 0 0 1.29E+08 1.35E+08 - - - 5.2948 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18573.18573.2 0.000783 20-Nov R.IFVFEPPPGVK.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 1228.6856 2.21 23688 18573 2 1228.689261 615.3501 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3587.2 - 455036 - - - 2.9829 - 2.164 0.397 - 339.8 1 2 0 0.0037 11 0 0 0 4.71E+06 2.13E+06 - - - 4.0604 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18574.18574.2 0.00827 14-Aug R.WVVPVLPK.G "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 936.5797 1.87 23689 18574 2 936.581219 469.2971 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3587.4 - 446914 - - - 1.6496 - 1.681 0.379 - 231.3 1 2 0 0.0015 8 0 0 0 7.20E+06 3.85E+06 - - - 3.4063 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.18575.18575.2 0.0806 14-Jun R.WVVPVLPK[136.11].G "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 944.5939 1.88 23690 18575 2 944.596582 473.3042 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3587.5 - 358445 - - - 2.8668 - 1.231 0.285 - 82.6 1 2 0 0.0027 8 0 0 0 7.16E+06 3.81E+06 - - - 1.772 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18576.18576.2 0.00014 22-Dec K.GGIVGMTLPIAR.D "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 1183.6747 1.45 23691 18576 2 1183.677971 592.8446 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 9.75 3587.6 - 227170 - - - 2.7516 - 1.774 0.461 - 375.2 1 2 0 0.0033 12 0 0 0 1.54E+07 1.06E+07 - - - 3.9532 0.9956 230117_WJC_METTL3_WT_vs_EV_F03.18587.18587.2 0.0107 16-Aug R.TTLLPGLLK.T sp|Q9NSD9|SYFB_HUMAN 1 954.6114 3.39 23701 18587 2 954.613879 478.313 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 8.41 3588.8 - 1.39E+06 - - - 2.6304 - 1.347 0.199 - 154.3 1 2 0 0.0025 9 0 0 0 2.18E+07 6.41E+06 - - - 1.3718 1 230117_WJC_METTL3_WT_vs_EV_F03.18588.18588.2 0.00255 18-Oct R.VLGLGLGC[160.03]LR.L "sp|Q9BRJ7|TIRR_HUMAN,tr|W4VSQ8|W4VSQ8_HUMAN,tr|K7EIN2|K7EIN2_HUMAN,tr|K7ENA3|K7ENA3_HUMAN" 4 1056.6114 3.84 23702 18588 2 1056.615304 529.313 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3588.9 - 1.17E+06 - - - 3.709 - 2.269 0.479 - 310.8 1 2 0 0.0039 10 0 0 0 2.02E+07 5.26E+06 - - - 4.8647 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.18591.18591.2 0.057 14-Sep R.EALAFIIR[166.11].S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 941.5574 1.2 23705 18591 2 941.559896 471.786 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3589.2 - 674979 - - - 2.6807 - 1.86 0.306 - 332 1 2 0 0.0025 8 0 0 0 2.17E+07 1.80E+07 - - - 3.172 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.18592.18592.2 2.1 16-Jul R.GNLLLEQER.Q "sp|Q6ZSZ5|ARHGI_HUMAN,tr|A0A3B3IPE9|A0A3B3IPE9_HUMAN,tr|A0A590UK10|A0A590UK10_HUMAN,tr|M0QZS0|M0QZS0_HUMAN,tr|A0A087WZG4|A0A087WZG4_HUMAN,tr|A0A804CAZ4|A0A804CAZ4_HUMAN" 6 1070.572 1.88 23706 18592 2 1070.574051 536.2933 Rho guanine nucleotide exchange factor 18 OS=Homo sapiens OX=9606 GN=ARHGEF18 PE=1 SV=4 4.53 3589.3 - 649690 - - - 1.8943 - 1.53 0.161 - 179.8 1 2 0 0.002 9 0 0 0 9.19E+06 4.87E+06 - - - 1.4598 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18593.18593.2 0.032 18-Oct R.GIVILMVDEK.M sp|P42285|MTREX_HUMAN 1 1115.626 1.37 23707 18593 2 1115.628281 558.8203 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 3589.3 - 569152 - - - 2.0159 - 2.325 0.363 - 357 1 2 0 0.0022 10 0 0 0 7.67E+06 5.61E+06 - - - 4.0765 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.18594.18594.2 0.0122 16-Sep R.TTLLPGLLK[136.11].T sp|Q9NSD9|SYFB_HUMAN 1 962.6256 3.39 23708 18594 2 962.628206 482.3201 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 8.41 3589.4 - 511989 - - - 2.7404 - 1.368 0.288 - 181.6 1 2 0 0.0026 9 0 0 0 2.18E+07 6.41E+06 - - - 2.0739 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.18597.18597.2 0.0314 16-Aug R.LFENYIELK.A sp|Q96KP1|EXOC2_HUMAN 1 1167.6176 0.78 23711 18597 2 1167.62074 584.8161 Exocyst complex component 2 OS=Homo sapiens OX=9606 GN=EXOC2 PE=1 SV=1 4.53 3589.8 - 455118 - - - 2.7098 - 1.683 0.247 - 159.4 1 2 0 0.0032 9 0 0 0 3.22E+06 4.15E+06 - - - 2.3704 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18599.18599.2 0.00348 18-Dec K.TNVALMC[160.03]MLR.E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1207.5876 1.03 23713 18599 2 1207.590804 604.8011 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 7.91 3590 - 422798 - - - 2.6905 - 2.271 0.427 - 587 1 2 0 0.0032 10 0 0 0 4.58E+06 4.44E+06 - - - 4.4833 1 230117_WJC_METTL3_WT_vs_EV_F03.18604.18604.2 5.54E-07 14/30 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 21.64 23717 18604 2 1696.906898 849.4585 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3590.7 - 360316 - - - 2.6772 - 2.724 0.579 - 465.4 1 2 0 0.0045 16 0 0 0 5.81E+07 2.68E+06 - - - 5.7798 1 230117_WJC_METTL3_WT_vs_EV_F03.18606.18606.3 9.55E-12 20/60 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 22.66 23719 18606 3 1686.902915 563.3053 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3590.9 - 7.29E+06 - - - 5.2345 - 3.822 0.624 - 565.5 1 2 0 0.0088 16 0 0 0 4.03E+07 1.78E+06 - - - 8.9348 1 230117_WJC_METTL3_WT_vs_EV_F03.18607.18607.2 2.81E-07 22-Dec K.FGEAIGMGFPVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1251.6322 0.96 23720 18607 2 1251.639097 626.8234 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3591 - 4.77E+06 - - - 5.5264 - 2.408 0.604 - 457.4 1 2 0 0.0069 12 0 0 0 1.29E+08 1.35E+08 - - - 5.8122 1 230117_WJC_METTL3_WT_vs_EV_F03.18608.18608.2 2.08E-07 15/22 R.LLYMAIDGVAPR.A sp|Q9H0D6|XRN2_HUMAN 1 1317.7115 1.08 23721 18608 2 1317.716884 659.863 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3591.1 - 1.22E+06 - - - 4.0912 - 2.703 0.529 - 1081.5 1 2 0 0.0054 12 0 0 0 4.75E+07 4.40E+07 - - - 5.5628 0.9567 230117_WJC_METTL3_WT_vs_EV_F03.18609.18609.2 1.55 12-Jul R.LQFLFAK.D "sp|Q7Z3K3|POGZ_HUMAN,tr|H0YCT3|H0YCT3_HUMAN" 2 865.5062 1.02 23722 18609 2 865.510383 433.7604 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 8.75 3591.3 - 1.13E+06 - - - 4.8619 - 1.291 0.118 - 128 1 2 0 0.0042 7 0 0 0 3.79E+06 3.70E+06 - - - 0.7205 0.9866 230117_WJC_METTL3_WT_vs_EV_F03.18615.18615.2 0.127 12-May R.LQFLFAK[136.11].D "sp|Q7Z3K3|POGZ_HUMAN,tr|H0YCT3|H0YCT3_HUMAN" 2 873.5204 1.73 23728 18615 2 873.525425 437.7675 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 8.75 3592 - 523100 - - - 5.7812 - 1.43 0.282 - 63.7 1 2 0 0.005 7 0 0 0 3.13E+06 1.81E+06 - - - 2.2556 1 230117_WJC_METTL3_WT_vs_EV_F03.18622.18622.2 0.000115 20-Nov R.VYPQAVYFPIR.T "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1351.7289 1.28 23735 18622 2 1351.735818 676.8717 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.56 3592.9 - 104791 - - - 5.149 - 2.247 0.461 - 549.3 1 2 0 0.007 11 0 0 0 1.96E+06 1.52E+06 - - - 4.6339 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.18626.18626.2 0.186 20-Jul K.LVFLGLDNAGK.T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1145.6445 1.56 23737 18626 2 1145.6484 573.8295 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3593.4 - 9.95E+06 - - - 3.44 - 1.652 0.33 - 127.6 1 2 0 0.0039 11 0 0 0 3.57E+08 2.29E+08 - - - 2.8351 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18627.18627.2 0.0033 20-Oct K.LVFLGLDNAGK[136.11].T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1153.6587 1.56 23738 18627 2 1153.66228 577.8366 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3593.4 - 7.26E+06 - - - 3.1387 - 1.98 0.441 - 286.7 1 2 0 0.0036 11 0 0 0 3.56E+08 2.28E+08 - - - 4.145 1 230117_WJC_METTL3_WT_vs_EV_F03.18628.18628.2 3.07E-05 22-Dec R.LLYMAIDGVAPR[166.11].A sp|Q9H0D6|XRN2_HUMAN 1 1327.7198 1.08 23739 18628 2 1327.724538 664.8672 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3593.5 - 3.40E+06 - - - 3.5964 - 2.363 0.561 - 570.6 1 2 0 0.0048 12 0 0 0 4.75E+07 4.40E+07 - - - 5.4457 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18629.18629.2 6.47E-05 16-Aug R.LVLDWDSVR.A "sp|Q68EM7|RHG17_HUMAN,tr|C9IZD3|C9IZD3_HUMAN,tr|I3L4P6|I3L4P6_HUMAN" 3 1101.5819 2.24 23740 18629 2 1101.584061 551.7982 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4.21 3593.5 - 3.05E+06 - - - 1.9989 - 1.75 0.506 - 244.7 1 2 0 0.0022 9 0 0 0 3.27E+07 1.46E+07 - - - 4.3966 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.18632.18632.2 0.362 12-Jun R.NITLWLK[136.11].Y "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 894.5418 0.69 23743 18632 2 894.541901 448.2782 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 8.75 3593.8 - 746013 - - - 0.0693 - 1.303 0.228 - 114.1 1 2 0 0.0001 7 0 0 0 4.45E+06 6.41E+06 - - - 1.5636 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18633.18633.2 0.000327 20-Dec K.NPLIINSIIDK[136.11].A "sp|Q9UNQ2|DIM1_HUMAN,tr|A0A494C0G7|A0A494C0G7_HUMAN,tr|B4DRY2|B4DRY2_HUMAN,tr|A0A7P0T8X7|A0A7P0T8X7_HUMAN,tr|A0A0C4DGB1|A0A0C4DGB1_HUMAN,tr|A0A7P0T967|A0A7P0T967_HUMAN,tr|A0A7P0T9J1|A0A7P0T9J1_HUMAN,tr|A0A7P0Z4I0|A0A7P0Z4I0_HUMAN,tr|A0A7P0T9Y7|A0A7P0T9Y7_HUMAN,tr|D6RCL3|D6RCL3_HUMAN" 10 1246.7376 0.96 23744 18633 2 1246.741338 624.3761 Probable dimethyladenosine transferase OS=Homo sapiens OX=9606 GN=DIMT1 PE=1 SV=1 5.84 3593.9 - 731772 - - - 2.9677 - 2.308 0.316 - 545.1 1 2 0 0.0037 11 0 0 0 6.61E+06 6.87E+06 - - - 3.6364 0.9781 230117_WJC_METTL3_WT_vs_EV_F03.18634.18634.2 1.88 12-Jun R.ALLFIPR.R "sp|P08238|HS90B_HUMAN,sp|O00585|CCL21_HUMAN,tr|Q5VZ73|Q5VZ73_HUMAN" 3 828.5222 1.81 23745 18634 2 828.522908 415.2684 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 9.79 3594 - 545600 - - - 0.904 - 1.252 0.029 - 148.3 1 2 0 0.0007 7 0 0 0 6.75E+06 3.72E+06 - - - -0.0329 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18635.18635.2 0.0112 16-Nov R.LNILDTLSK.F "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1015.5914 1.5 23746 18635 2 1015.593818 508.803 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 5.84 3594.1 - 517498 - - - 2.4193 - 2.013 0.302 - 321.7 1 2 0 0.0025 9 0 0 0 3.99E+06 2.66E+06 - - - 3.2949 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.18639.18639.2 1.65E-05 22-Aug R.VIQEGLEGLVLK.D sp|P49916|DNLI3_HUMAN 1 1296.7653 3.26 23750 18639 2 1296.77002 649.3899 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 4.53 3594.6 - 328999 - - - 3.6375 - 1.947 0.462 - 149.6 1 2 0 0.0047 12 0 0 0 2.39E+06 7.34E+05 - - - 4.205 0.9825 230117_WJC_METTL3_WT_vs_EV_F03.18640.18640.2 8.67 12-May K.ELLALLK[136.11].C "sp|Q92560|BAP1_HUMAN,sp|Q8NA66|CNBD1_HUMAN,sp|Q8NGS7|O13C8_HUMAN,sp|Q8NGV5|O13D1_HUMAN,sp|Q8NGS4|O13F1_HUMAN,tr|A0A087WTB2|A0A087WTB2_HUMAN,tr|F8W6N3|F8W6N3_HUMAN,tr|H0Y8E8|H0Y8E8_HUMAN,tr|H0YC59|H0YC59_HUMAN,tr|A0A286YF94|A0A286YF94_HUMAN" 10 806.5357 0.23 23751 18640 2 806.537023 404.2751 Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Homo sapiens OX=9606 GN=BAP1 PE=1 SV=2 6.1 3594.7 - 203917 - - - 1.6515 - 1.217 0.06 - 87.8 1 2 0 0.0013 7 0 0 0 6.20E+06 2.71E+07 - - - 0.106 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18642.18642.2 0.0136 14-Aug R.EALAFIIR.S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 931.5491 1.2 23752 18642 2 931.55065 466.7818 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3594.9 - 1.88E+06 - - - 1.6617 - 1.809 0.263 - 266.3 1 2 0 0.0015 8 0 0 0 2.16E+07 1.81E+07 - - - 2.7708 1 230117_WJC_METTL3_WT_vs_EV_F03.18643.18643.2 0.0014 13/22 R.IGFDVVTLSGTR[166.11].G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1273.6906 0.88 23753 18643 2 1273.693421 637.8526 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.84 3595 - 728501 - - - 2.2368 - 2.398 0.45 - 469.7 1 2 0 0.0028 12 0 0 0 5.34E+06 6.08E+06 - - - 4.6651 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.18644.18644.2 0.0389 16-Jun R.LVLDWDSVR[166.11].A "sp|Q68EM7|RHG17_HUMAN,tr|C9IZD3|C9IZD3_HUMAN,tr|I3L4P6|I3L4P6_HUMAN" 3 1111.5901 2.24 23754 18644 2 1111.591789 556.8023 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4.21 3595 - 1.69E+06 - - - 1.4934 - 1.34 0.277 - 97.9 1 2 0 0.0017 9 0 0 0 3.28E+07 1.46E+07 - - - 1.9331 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.18645.18645.2 0.217 12-Jul K.LIFYDLR[166.11].G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 948.5308 1.11 23755 18645 2 948.532776 475.2727 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3595.1 - 1.45E+06 - - - 2.059 - 1.408 0.222 - 192.3 1 2 0 0.002 7 0 0 0 3.89E+07 3.50E+07 - - - 1.7643 0.9958 230117_WJC_METTL3_WT_vs_EV_F03.18648.18648.2 0.152 16-Jul R.ALLLSTYIK.F "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|A0A0G2JS82|A0A0G2JS82_HUMAN,tr|A0A0G2JQM1|A0A0G2JQM1_HUMAN" 4 1020.6219 1.09 23758 18648 2 1020.621134 511.3182 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 8.63 3595.3 - 808343 - - - -0.7829 - 1.732 0.179 - 124.9 2 2 0 -0.0008 9 0 0 0 9.07E+06 8.28E+06 - - - 1.8175 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18649.18649.2 0.000363 20-Sep R.VLPSITTEILK.S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1212.7329 1.34 23759 18649 2 1212.734737 607.3737 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 3595.4 - 807622 - - - 1.4818 - 1.879 0.419 - 233.1 1 2 0 0.0018 11 0 0 0 6.39E+07 4.77E+07 - - - 3.8415 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.18651.18651.2 0.000128 20-Nov R.VLPSITTEILK[136.11].S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1220.7471 1.34 23761 18651 2 1220.750307 611.3808 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 3595.5 - 656756 - - - 2.5943 - 1.759 0.269 - 322.9 1 2 0 0.0032 11 0 0 0 6.39E+07 4.77E+07 - - - 2.5546 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.18653.18653.2 2.9 12-Aug R.NAFDLFK[136.11].L "sp|Q99549|MPP8_HUMAN,tr|A0A0A0MT47|A0A0A0MT47_HUMAN" 2 861.4476 0.98 23763 18653 2 861.448299 431.7311 M-phase phosphoprotein 8 OS=Homo sapiens OX=9606 GN=MPHOSPH8 PE=1 SV=2 5.84 3595.8 - 532847 - - - 0.8068 - 1.52 0.184 - 219.7 1 2 0 0.0007 7 0 0 0 3.01E+06 3.09E+06 - - - 1.7265 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.18660.18660.2 0.235 12-Jul K.LIFYDLR.G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 938.5226 1.1 23768 18660 2 938.52505 470.2686 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3596.7 - 2.17E+06 - - - 2.6606 - 1.438 0.345 - 190.7 1 2 0 0.0025 7 0 0 0 4.01E+07 3.63E+07 - - - 2.7394 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.18661.18661.2 0.0136 14-Aug R.ILFFNTPK.K "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 978.5539 1.06 23769 18661 2 978.55629 490.2842 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 8.75 3596.7 - 2.57E+06 - - - 2.4894 - 1.581 0.35 - 178.2 1 2 0 0.0024 8 0 0 0 5.05E+07 4.78E+07 - - - 3.0068 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18662.18662.2 0.000234 18-Sep K.ELLTSFGPLK[136.11].A "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1111.6369 1.51 23770 18662 2 1111.639328 556.8257 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6.1 3596.8 - 2.79E+06 - - - 2.2192 - 2.051 0.419 - 230.7 1 2 0 0.0025 10 0 0 0 5.35E+07 3.54E+07 - - - 4.14 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.18666.18666.2 0.0104 16-Sep R.VLAINILGR.F sp|O43747|AP1G1_HUMAN 1 967.6179 0.32 23774 18666 2 967.617781 484.8162 AP-1 complex subunit gamma-1 OS=Homo sapiens OX=9606 GN=AP1G1 PE=1 SV=5 9.72 3597 - 385851 - - - -0.0723 - 1.918 0.312 - 233.7 1 2 0 -0.0001 9 0 0 0 5.45E+06 1.68E+07 - - - 3.2296 1 230117_WJC_METTL3_WT_vs_EV_F03.18667.18667.2 7.96E-07 26-Sep K.IVIPNEESVVIYYK[136.11].L sp|P42285|MTREX_HUMAN 1 1672.9167 0.81 23775 18667 2 1672.920699 837.4656 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.53 3597.2 - 318936 - - - 2.3755 - 1.961 0.579 - 155.9 1 2 0 0.004 14 0 0 0 2.51E+06 3.11E+06 - - - 5.0062 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18668.18668.2 0.000539 26-Nov K.YILVTGGVISGIGK.G "sp|P17812|PYRG1_HUMAN,sp|Q9NRF8|PYRG2_HUMAN,tr|A0A3B3ITH9|A0A3B3ITH9_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 7 1375.8075 2.14 23776 18668 2 1375.81008 688.911 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 8.59 3597.3 - 224006 - - - 1.8738 - 2.156 0.452 - 196 1 2 0 0.0026 14 0 0 0 4.44E+06 2.07E+06 - - - 4.3066 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.18673.18673.2 0.00444 14-Sep R.QAFYFALR.D "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1014.5287 1.23 23779 18673 2 1014.5318 508.2716 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.75 3597.9 - 853145 - - - 3.0546 - 1.586 0.348 - 272.1 1 2 0 0.0031 8 0 0 0 8.47E+06 6.89E+06 - - - 3.0014 0.9943 230117_WJC_METTL3_WT_vs_EV_F03.18674.18674.2 0.425 12-Jun R.VLVWDLR[166.11].N "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 909.5312 1.83 23780 18674 2 909.533698 455.7729 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.81 3598 - 2.97E+06 - - - 2.7926 - 1.413 0.15 - 188.6 1 2 0 0.0025 7 0 0 0 4.44E+07 2.42E+07 - - - 1.2435 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18675.18675.2 2.16E-06 14-Sep K.C[160.03]QLLFALK.V "sp|Q9BRJ7|TIRR_HUMAN,tr|K7EIN2|K7EIN2_HUMAN" 2 991.5525 0.83 23781 18675 2 991.55581 496.7835 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3598.1 - 707334 - - - 3.3644 - 1.856 0.467 - 309.6 1 2 0 0.0033 8 0 0 0 9.72E+06 1.18E+07 - - - 4.3544 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.18676.18676.2 0.005 14-Jun R.ELSPLFLR.F sp|O75691|UTP20_HUMAN 1 973.5597 0.88 23782 18676 2 973.561936 487.7871 Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3 6.1 3598.2 - 582231 - - - 2.3306 - 1.446 0.312 - 134 1 2 0 0.0023 8 0 0 0 6.15E+06 6.96E+06 - - - 2.457 0.986 230117_WJC_METTL3_WT_vs_EV_F03.18679.18679.2 0.563 12-Jul R.LTIAILR.H "sp|Q5XPI4|RN123_HUMAN,sp|Q96B70|LENG9_HUMAN,tr|C9J266|C9J266_HUMAN,tr|A0A087WVD1|A0A087WVD1_HUMAN,tr|C9JS59|C9JS59_HUMAN" 5 798.5327 2.41 23785 18679 2 798.534588 400.2736 E3 ubiquitin-protein ligase RNF123 OS=Homo sapiens OX=9606 GN=RNF123 PE=1 SV=1 9.75 3598.6 - 317326 - - - 2.3343 - 1.534 0.001 - 218.6 1 2 0 0.0019 7 0 0 0 6.61E+07 2.74E+07 - - - 0.4036 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.18680.18680.2 0.0342 18-Jul R.LWTPPEDYRL.- "sp|Q9BYD1|RM13_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 2 1288.6452 1.79 23786 18680 2 1288.645746 645.3299 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.37 3598.8 - 214466 - - - 0.433 - 1.495 0.245 - 199.2 1 2 0 0.0006 10 0 0 0 1.64E+07 9.15E+06 - - - 1.9729 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18685.18685.2 0.0589 16-Oct R.FEALNLSFK.N "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 12 1067.5651 1.36 23789 18685 2 1067.568263 534.7898 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 6 3599.3 - 4.24E+06 - - - 2.9188 - 1.938 0.34 - 275.5 1 2 0 0.0031 9 0 0 0 5.85E+07 4.30E+07 - - - 3.4655 0.9938 230117_WJC_METTL3_WT_vs_EV_F03.18687.18687.2 0.818 12-Jul R.TLIGFLR.S "sp|O15116|LSM1_HUMAN,tr|E5RH18|E5RH18_HUMAN,tr|E5RJ47|E5RJ47_HUMAN" 3 818.5014 1.72 23791 18687 2 818.502354 410.258 U6 snRNA-associated Sm-like protein LSm1 OS=Homo sapiens OX=9606 GN=LSM1 PE=1 SV=1 9.41 3599.5 - 1.13E+06 - - - 1.1362 - 1.281 0.134 - 196.8 1 2 0 0.0009 7 0 0 0 1.11E+07 6.44E+06 - - - 0.8151 0.9837 230117_WJC_METTL3_WT_vs_EV_F03.18689.18689.2 0.223 18-Jul K.AIAINTFLPK[136.11].N sp|Q92615|LAR4B_HUMAN 1 1094.6579 1.14 23793 18689 2 1094.660985 548.3362 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3599.7 - 712163 - - - 2.7899 - 1.433 0.075 - 113.5 2 2 0 0.0031 10 0 0 0 8.76E+06 7.67E+06 - - - 0.4637 0.9954 230117_WJC_METTL3_WT_vs_EV_F03.18690.18690.2 0.168 16-Jul K.ALLSALELK.K sp|P49454|CENPF_HUMAN 1 956.5906 1.09 23794 18690 2 956.590768 479.3026 Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3 6.05 3599.8 - 546061 - - - 0.1411 - 1.549 0.132 - 105.8 1 2 0 0.0001 9 0 0 0 3.91E+06 3.58E+06 - - - 1.2819 1 230117_WJC_METTL3_WT_vs_EV_F03.18692.18692.2 7.65E-07 16/26 R.ALMGSPQLVAAVVR.T "sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9J826|C9J826_HUMAN" 5 1410.8017 999 23796 18692 2 1410.806087 706.4081 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 9.79 3600 - 436518 - - - 3.106 - 2.889 0.549 - 865.1 1 2 0 0.0044 14 0 0 0 1.91E+07 0.00E+00 - - - 5.7568 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18693.18693.2 6.95E-05 24-Nov K.ILTPLVSLDTPGK.A "sp|Q9HC38|GLOD4_HUMAN,tr|I3L1I0|I3L1I0_HUMAN,tr|F6TLX2|F6TLX2_HUMAN" 3 1352.7915 0.86 23797 18693 2 1352.792024 677.403 Glyoxalase domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GLOD4 PE=1 SV=1 5.84 3600.1 - 250022 - - - 0.374 - 1.7 0.42 - 328.8 1 2 0 0.0005 13 0 0 0 1.49E+06 1.74E+06 - - - 3.5048 0.998 230117_WJC_METTL3_WT_vs_EV_F03.18699.18699.2 0.0321 14-Jul R.FLIQNVLR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1011.6105 1.5 23802 18699 2 1011.613676 506.8125 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.75 3601 - 824806 - - - 3.1682 - 1.59 0.266 - 158.5 1 2 0 0.0032 8 0 0 0 1.36E+08 9.08E+07 - - - 2.4033 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.18700.18700.2 0.00552 12-Jun R.EFIEMWR[166.11].L "sp|Q7L0Y3|TM10C_HUMAN,tr|C9JVB6|C9JVB6_HUMAN" 2 1019.4774 0.85 23803 18700 2 1019.480805 510.746 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 4.53 3601.1 - 746620 - - - 3.3321 - 1.54 0.347 - 143.4 1 2 0 0.0034 7 0 0 0 5.19E+06 6.13E+06 - - - 2.971 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.18701.18701.2 0.164 18-Sep K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.14 23804 18701 2 1086.647857 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3601.2 - 738322 - - - 3.797 - 1.937 0.286 - 205.3 1 2 0 0.0041 10 0 0 0 8.76E+06 7.67E+06 - - - 2.9975 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.18703.18703.2 0.0159 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 8.62 23806 18703 2 1006.574522 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3601.5 - 653839 - - - 4.5938 - 1.592 0.337 - 228.5 1 2 0 0.0046 9 0 0 0 1.83E+07 2.12E+06 - - - 2.8739 0.9597 230117_WJC_METTL3_WT_vs_EV_F03.18705.18705.2 0.607 16-Aug K.ALLSALELK[136.11].K sp|P49454|CENPF_HUMAN 1 964.6048 1.1 23808 18705 2 964.610517 483.3097 Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3 6.05 3601.7 - 268807 - - - 5.8926 - 1.615 0.156 - 122.8 4 2 0 0.0057 9 0 0 0 3.95E+06 3.58E+06 - - - 1.3092 0.9586 230117_WJC_METTL3_WT_vs_EV_F03.18709.18709.2 0.00147 16-Jul R.MVNHFIAEF.K "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1106.5219 - 23810 18709 2 1106.524074 554.2682 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.22 3602.3 - 2.77E+06 - - - 1.9638 - 1.441 0.425 - 175.3 1 1 0 0.0022 9 0 0 0 - - - - - 3.2363 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18710.18710.2 4.79E-05 16-Oct R.SPTWFGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1059.5502 0.97 23811 18710 2 1059.551955 530.7824 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3602.3 - 1.91E+06 - - - 1.6894 - 1.901 0.481 - 501 1 2 0 0.0018 9 0 0 0 5.08E+08 5.22E+08 - - - 4.4515 0.999 230117_WJC_METTL3_WT_vs_EV_F03.18711.18711.2 0.0027 14-Sep R.FLIQNVLR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1001.6022 1.5 23812 18711 2 1001.60533 501.8084 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.75 3602.4 - 5.64E+06 - - - 3.124 - 1.801 0.318 - 322.8 1 2 0 0.0031 8 0 0 0 1.36E+08 9.08E+07 - - - 3.1632 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18713.18713.2 0.167 20-Oct K.YLLDSC[160.03]APLLR.Y sp|Q92616|GCN1_HUMAN 1 1319.6908 1.02 23814 18713 2 1319.692546 660.8527 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.83 3602.6 - 1.33E+06 - - - 1.3549 - 1.914 0.271 - 294.9 1 2 0 0.0018 11 0 0 0 4.51E+06 4.43E+06 - - - 2.7983 1 230117_WJC_METTL3_WT_vs_EV_F03.18716.18716.2 1.40E-05 20-Dec K.YLLDSC[160.03]APLLR[166.11].Y sp|Q92616|GCN1_HUMAN 1 1329.699 1.02 23817 18716 2 1329.700915 665.8568 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.83 3602.9 - 1.12E+06 - - - 1.4191 - 1.999 0.53 - 484.8 1 2 0 0.0019 11 0 0 0 4.51E+06 4.43E+06 - - - 4.8288 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18717.18717.2 0.00489 18-Nov R.FEELC[160.03]SDLFR.S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1314.5914 36.9 23818 18717 2 1314.594869 658.303 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.14 3603.1 - 1.04E+06 - - - 2.6099 - 2.06 0.43 - 448.2 1 2 0 0.0034 10 0 0 0 4.30E+06 1.17E+05 - - - 4.2332 1 230117_WJC_METTL3_WT_vs_EV_F03.18720.18720.2 1.86E-05 20-Oct R.SLMIQTLEAVK[136.11].R "sp|Q9Y2R9|RT07_HUMAN,tr|J3QKW2|J3QKW2_HUMAN,tr|J3QLS3|J3QLS3_HUMAN,tr|J3QQS1|J3QQS1_HUMAN,tr|J3KSI8|J3KSI8_HUMAN" 5 1239.6988 0.97 23821 18720 2 1239.700656 620.8567 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 5.72 3603.4 - 817252 - - - 1.4891 - 2.074 0.492 - 274.4 1 2 0 0.0018 11 0 0 0 5.98E+06 6.18E+06 - - - 4.6477 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18722.18722.2 0.000405 18-Dec R.IPDEIIDMVK.E "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1171.6159 2.03 23823 18722 2 1171.617844 586.8152 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 4.03 3603.7 - 620119 - - - 1.6917 - 1.925 0.473 - 401 1 2 0 0.002 10 0 0 0 4.83E+07 2.38E+07 - - - 4.3621 1 230117_WJC_METTL3_WT_vs_EV_F03.18724.18724.2 0.00104 18-Nov K.LYGEFADPFK.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1185.5706 2.35 23825 18724 2 1185.573888 593.7926 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3604 - 444767 - - - 2.7514 - 2.053 0.521 - 378.7 1 2 0 0.0033 10 0 0 0 1.54E+07 6.54E+06 - - - 4.8959 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18725.18725.2 0.00037 24-Dec R.LIEETISIAMATK[136.11].E "sp|O95249|GOSR1_HUMAN,tr|E9PCW1|E9PCW1_HUMAN,tr|G5E9T8|G5E9T8_HUMAN" 3 1426.7833 0.45 23826 18725 2 1426.783323 714.3989 Golgi SNAP receptor complex member 1 OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 4.53 3604.1 - 376213 - - - 0.0385 - 2.349 0.453 - 379 1 2 0 0.0001 13 0 0 0 1.64E+06 3.65E+06 - - - 4.5786 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.18730.18730.2 0.0611 16-Sep R.SLDLLGLEK.L "sp|O95551|TYDP2_HUMAN,tr|X6R5A3|X6R5A3_HUMAN" 2 986.5648 99.3 23830 18730 2 986.569325 494.2897 Tyrosyl-DNA phosphodiesterase 2 OS=Homo sapiens OX=9606 GN=TDP2 PE=1 SV=1 4.37 3604.7 - 1.33E+06 - - - 4.5745 - 1.706 0.352 - 238.7 1 2 0 0.0045 9 0 0 0 1.87E+07 1.89E+05 - - - 3.1848 0.9835 230117_WJC_METTL3_WT_vs_EV_F03.18731.18731.2 0.144 12-Apr R.VLVWDLR.N "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 899.5229 0.88 23831 18731 2 899.525168 450.7687 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.81 3604.8 - 490959 - - - 2.5347 - 1.099 0.156 - 67.7 2 2 0 0.0023 7 0 0 0 4.57E+07 5.20E+07 - - - 0.3571 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18732.18732.2 0.0368 18-Sep R.YDLGGLVMVK.D sp|Q15274|NADC_HUMAN 1 1093.5842 0.43 23832 18732 2 1093.586792 547.7994 Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Homo sapiens OX=9606 GN=QPRT PE=1 SV=3 5.83 3604.8 - 1.45E+06 - - - 2.4004 - 1.881 0.413 - 206.4 1 2 0 0.0026 10 0 0 0 4.16E+07 9.77E+07 - - - 3.8541 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18733.18733.2 0.000106 16-Aug K.LFTTMELMR.W sp|O00232|PSD12_HUMAN 1 1140.5671 2.27 23833 18733 2 1140.568469 571.2908 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 6 3604.9 - 884780 - - - 1.1678 - 1.801 0.44 - 196.5 1 2 0 0.0013 9 0 0 0 2.29E+07 1.01E+07 - - - 3.9925 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18735.18735.2 0.0121 18-Jul R.LWTPPEDYR[166.11]L.- "sp|Q9BYD1|RM13_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 2 1298.6535 1.79 23835 18735 2 1298.656723 650.334 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.37 3605 - 536308 - - - 2.5141 - 1.731 0.367 - 253.4 1 2 0 0.0033 10 0 0 0 1.64E+07 9.15E+06 - - - 3.2822 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.18738.18738.2 0.00428 14-Jul K.FEFLGINR.Q sp|Q8N3X1|FNBP4_HUMAN 1 994.5236 1.09 23838 18738 2 994.522887 498.2691 Formin-binding protein 4 OS=Homo sapiens OX=9606 GN=FNBP4 PE=1 SV=3 6 3605.2 - 363975 - - - -0.733 - 1.517 0.312 - 159.1 1 2 0 -0.0007 8 0 0 0 7.60E+06 7.00E+06 - - - 2.6021 0.9703 230117_WJC_METTL3_WT_vs_EV_F03.18742.18742.2 2.01 12-May R.VMFEVWR.N sp|Q09161|NCBP1_HUMAN 1 965.4793 0.71 23842 18742 2 965.480825 483.7469 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 5.97 3605.6 - 251420 - - - 1.5712 - 1.01 0.11 - 53.2 2 2 0 0.0015 7 0 0 0 1.49E+06 2.11E+06 - - - -0.25 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18752.18752.2 0.0152 16-Aug K.LFTTMELMR[166.11].W sp|O00232|PSD12_HUMAN 1 1150.5754 2.29 23850 18752 2 1150.576 576.295 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 6 3606.6 - 772243 - - - 0.5154 - 1.774 0.362 - 197.3 1 2 0 0.0006 9 0 0 0 2.29E+07 9.97E+06 - - - 3.373 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.18760.18760.2 0.0412 16-Sep R.ALVAVLLSR.T sp|Q92616|GCN1_HUMAN 1 940.607 1.08 23856 18760 2 940.607403 471.3108 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.79 3607.6 - 359028 - - - 0.4795 - 2.04 0.208 - 276.9 1 2 0 0.0005 9 0 0 0 2.02E+07 1.87E+07 - - - 2.6397 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.18761.18761.2 1.3 16-Nov R.ALVAVLLSR[166.11].T sp|Q92616|GCN1_HUMAN 1 950.6152 1.08 23857 18761 2 950.615589 476.3149 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.79 3607.7 - 735951 - - - 0.3861 - 1.82 0.135 - 629.1 1 2 0 0.0004 9 0 0 0 2.02E+07 1.87E+07 - - - 1.7705 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18765.18765.2 0.217 16-Oct K.GLALWEAYR.E "sp|Q15020|SART3_HUMAN,tr|F8VVK9|F8VVK9_HUMAN,tr|A0A494C0L2|A0A494C0L2_HUMAN,tr|F8W667|F8W667_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN,tr|F8VZM2|F8VZM2_HUMAN" 6 1077.5607 2.59 23859 18765 2 1077.559961 539.7876 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 3608.2 - 3.07E+06 - - - -0.7136 - 2.214 0.431 - 607.5 1 2 0 -0.0008 9 0 0 0 2.87E+07 1.11E+07 - - - 4.5235 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18768.18768.2 2.84E-05 22-Oct K.IIATVLMTEDIK[136.11].L "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 1353.7669 0.25 23862 18768 2 1353.7686 677.8907 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 3608.5 - 1.67E+06 - - - 1.2639 - 2.164 0.44 - 252.9 1 2 0 0.0017 12 0 0 0 2.70E+06 1.07E+07 - - - 4.3215 1 230117_WJC_METTL3_WT_vs_EV_F03.18769.18769.2 2.28E-06 20-Sep K.LYLNETFSELR.L "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C3Z5|H7C3Z5_HUMAN" 3 1383.7034 3.34 23863 18769 2 1383.707439 692.859 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 4.53 3608.6 - 1.06E+06 - - - 2.8966 - 2.314 0.561 - 268.8 1 2 0 0.004 11 0 0 0 7.85E+06 2.35E+06 - - - 5.4529 0.9894 230117_WJC_METTL3_WT_vs_EV_F03.18770.18770.2 0.246 12-Jul R.YILDYLR[166.11].D "sp|Q96CX2|KCD12_HUMAN,sp|Q68DU8|KCD16_HUMAN" 2 964.5257 1.6 23864 18770 2 964.52705 483.2701 BTB\POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1 5.83 3608.8 - 962155 - - - 1.3603 - 1.379 0.05 - 193.1 1 2 0 0.0013 7 0 0 0 1.87E+07 1.17E+07 - - - 0.4281 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18776.18776.2 0.00486 20-Dec K.IGDFGLVTSLK.N "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 3 1148.6441 522.79 23868 18776 2 1148.644333 575.3293 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 5.84 3609.5 - 2.79E+06 - - - 0.1811 - 2.372 0.305 - 295.8 1 2 0 0.0002 11 0 0 0 4.00E+07 7.64E+04 - - - 3.6303 0.9967 230117_WJC_METTL3_WT_vs_EV_F03.18777.18777.2 0.00226 20-Sep R.ELAMQTFGVLK[136.11].E sp|Q9NVP1|DDX18_HUMAN 1 1243.6726 0.001 23869 18777 2 1243.678885 622.8436 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 6.1 3609.5 - 1.15E+06 - - - 5.0576 - 1.804 0.37 - 151.8 1 2 0 0.0063 11 0 0 0 0.00E+00 3.11E+06 - - - 3.368 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18781.18781.2 0.00128 18-Nov R.ILVATNLFGR.G "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 6 1102.6499 1.34 23871 18781 2 1102.650168 552.3322 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 9.75 3610 - 300063 - - - 0.2621 - 1.989 0.41 - 373.7 1 2 0 0.0003 10 0 0 0 3.88E+08 2.90E+08 - - - 3.9886 0.9511 230117_WJC_METTL3_WT_vs_EV_F03.18784.18784.2 0.0292 14-Jul K.NSLESYAF.N "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 929.4131 - 23874 18784 2 929.414232 465.7138 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4 3610.2 - 979587 - - - 1.2578 - 1.287 0.417 - 148.2 1 1 0 0.0012 8 0 0 0 - - - - - 2.8816 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18791.18791.2 0.675 14-Sep K.TVALWDLR.N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 972.5393 1.96 23879 18791 2 972.541052 487.2769 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3611 - 912672 - - - 1.8364 - 1.71 0.324 - 315.1 1 2 0 0.0018 8 0 0 0 6.37E+08 3.25E+08 - - - 3.0515 0.9874 230117_WJC_METTL3_WT_vs_EV_F03.18792.18792.2 0.688 14-Aug K.WEQFLLGR.A sp|Q9HBI5|CC014_HUMAN 1 1047.5502 3.04 23880 18792 2 1047.550906 524.7824 Uncharacterized protein C3orf14 OS=Homo sapiens OX=9606 GN=C3orf14 PE=2 SV=1 6 3611 - 354939 - - - 0.7074 - 0.972 0.192 - 156.4 1 2 0 0.0007 8 0 0 0 1.12E+07 3.70E+06 - - - 0.3732 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18798.18798.2 0.0649 16-Sep R.YLTVAAVFR.G "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 5 1038.5862 2.82 23884 18798 2 1038.587121 520.3004 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3611.7 - 1.14E+07 - - - 0.8714 - 1.872 0.392 - 259.6 1 2 0 0.0009 9 0 0 0 1.03E+09 3.66E+08 - - - 3.75 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18799.18799.2 0.0138 14-Aug K.TVALWDLR[166.11].N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 982.5475 1.96 23885 18799 2 982.547958 492.281 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3611.8 - 3.61E+06 - - - 0.4295 - 1.759 0.373 - 211.9 1 2 0 0.0004 8 0 0 0 6.37E+08 3.25E+08 - - - 3.4991 0.8481 230117_WJC_METTL3_WT_vs_EV_F03.18800.18800.2 1.92 16-Aug R.DIQEQPEDR[166.11].K sp|Q6NXP0|EFC12_HUMAN 1 1138.513 0.001 23886 18800 2 1138.518995 570.2638 EF-hand calcium-binding domain-containing protein 12 OS=Homo sapiens OX=9606 GN=EFCAB12 PE=1 SV=1 3.92 3611.9 - 1.72E+06 - - - 5.2648 - 1.25 0.039 - 64.5 1 2 0 0.006 9 0 0 0 0.00E+00 2.47E+07 - - - -0.0273 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.18801.18801.2 2.82E-06 20-Dec K.VANVSLLALYK.G sp|P62266|RS23_HUMAN 1 1189.7071 0.94 23887 18801 2 1189.704985 595.8608 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3612.1 - 1.02E+06 - - - -1.7441 - 2.632 0.385 - 618.7 1 2 0 -0.0021 11 0 0 0 1.09E+09 1.17E+09 - - - 4.5019 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.18803.18803.3 0.0154 13/40 R.ILVTLLHTLER[166.11].M sp|Q9BWD1|THIC_HUMAN 1 1316.8055 1.18 23889 18803 3 1316.807154 439.9425 "Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2" 6.75 3612.3 - 693408 - - - 1.2242 - 2.257 0.371 - 209.6 1 2 0 0.0016 11 0 0 0 1.06E+07 9.04E+06 - - - 4.9884 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18805.18805.3 0.000123 Dec-40 R.ILVTLLHTLER.M sp|Q9BWD1|THIC_HUMAN 1 1306.7973 1.18 23891 18805 3 1306.796136 436.6064 "Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2" 6.75 3612.6 - 648662 - - - -0.8693 - 2.274 0.387 - 243.4 1 2 0 -0.0011 11 0 0 0 1.06E+07 9.04E+06 - - - 5.1882 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18810.18810.2 0.0519 20-Dec K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 0.93 23894 18810 2 1197.720557 599.8679 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3613.2 - 1.15E+07 - - - -0.5869 - 2.471 0.407 - 502.4 1 2 0 -0.0007 11 0 0 0 1.09E+09 1.17E+09 - - - 4.4941 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18816.18816.2 0.141 16-Nov R.LDALLAELR[166.11].A sp|Q96L58|B3GT6_HUMAN 1 1022.6 1.09 23900 18816 2 1022.601455 512.3073 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 4.37 3613.9 - 1.33E+06 - - - 1.4561 - 2.431 0.223 - 376.8 1 2 0 0.0015 9 0 0 0 2.02E+07 1.84E+07 - - - 3.2575 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18817.18817.2 0.000338 13/22 K.TALALEVGDIVK.V sp|P46109|CRKL_HUMAN 1 1227.7075 23.06 23901 18817 2 1227.7096 614.861 Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1 4.37 3614 - 1.22E+06 - - - 1.748 - 2.045 0.489 - 349.9 1 2 0 0.0021 12 0 0 0 1.03E+07 4.44E+05 - - - 4.5344 1 230117_WJC_METTL3_WT_vs_EV_F03.18818.18818.2 2.12E-06 13/22 K.SLAMEMVLTGDR.L sp|P30084|ECHM_HUMAN 1 1321.637 1.92 23902 18818 2 1321.637036 661.8258 "Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4" 4.37 3614.1 - 739406 - - - 0.0212 - 2.599 0.512 - 395.4 1 2 0 0 12 0 0 0 7.37E+06 3.83E+06 - - - 5.3357 1 230117_WJC_METTL3_WT_vs_EV_F03.18820.18820.2 4.95E-07 20-Nov K.FLC[160.03]YLSQAGFR.V sp|Q7Z2T5|TRM1L_HUMAN 1 1360.6598 2.07 23904 18820 2 1360.660308 681.3372 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 8.22 3614.4 - 505142 - - - 0.3792 - 2.319 0.461 - 544.4 1 2 0 0.0005 11 0 0 0 8.71E+06 4.20E+06 - - - 4.7213 0.9391 230117_WJC_METTL3_WT_vs_EV_F03.18825.18825.2 1.69 12-May R.GLFDSFR.R "sp|Q96IK1|BOD1_HUMAN,sp|Q8IYS8|BD1L2_HUMAN,tr|C9JNZ5|C9JNZ5_HUMAN" 3 840.413 2.42 23907 18825 2 840.411335 421.2138 Biorientation of chromosomes in cell division protein 1 OS=Homo sapiens OX=9606 GN=BOD1 PE=1 SV=2 5.84 3615 - 305691 - - - -1.9847 - 1.02 0.164 - 96.6 1 2 0 -0.0017 7 0 0 0 8.88E+06 3.66E+06 - - - 0.3145 0.9036 230117_WJC_METTL3_WT_vs_EV_F03.18827.18827.2 0.0048 12-Aug L.SGFLVWR[166.11].R "sp|Q9NP84|TNR12_HUMAN,sp|Q96T88|UHRF1_HUMAN,tr|I3L1J9|I3L1J9_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 6 873.4736 1.26 23909 18827 2 873.473534 437.7441 Tumor necrosis factor receptor superfamily member 12A OS=Homo sapiens OX=9606 GN=TNFRSF12A PE=1 SV=1 9.47 3615.3 - 716926 - - - -0.1248 - 1.757 0.235 - 251.7 1 1 0 -0.0001 7 0 0 0 1.56E+07 1.24E+07 - - - 2.5625 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18834.18834.2 0.000363 16-Oct R.LDALLAELR.A sp|Q96L58|B3GT6_HUMAN 1 1012.5917 1.05 23914 18834 2 1012.592146 507.3031 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 4.37 3616.1 - 709698 - - - 0.4444 - 2.507 0.197 - 408.3 1 2 0 0.0004 9 0 0 0 1.90E+07 1.82E+07 - - - 3.1549 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.18835.18835.2 0.0123 14-Aug R.AEWLLAVR.S sp|Q9NRN7|ADPPT_HUMAN 1 956.5444 2.72 23915 18835 2 956.543708 479.2795 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2 6.05 3616.2 - 704942 - - - -0.6722 - 1.473 0.337 - 235.2 1 2 0 -0.0006 8 0 0 0 3.32E+07 1.22E+07 - - - 2.698 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.18837.18837.2 0.324 14-Aug R.ILLTLGIR.L "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 897.6011 1.05 23917 18837 2 897.600549 449.8078 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 9.75 3616.4 - 411997 - - - -0.6562 - 1.825 0.314 - 194.4 1 2 0 -0.0006 8 0 0 0 1.00E+07 9.56E+06 - - - 3.1744 0.9716 230117_WJC_METTL3_WT_vs_EV_F03.18840.18840.2 0.107 12-Jul K.WMGIAFR[166.11].L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 889.4508 1.29 23918 18840 2 889.450518 445.7327 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.75 3616.8 - 1.56E+06 - - - -0.3159 - 0.99 0.153 - 172 1 2 0 -0.0003 7 0 0 0 2.95E+07 2.28E+07 - - - 0.1391 1 230117_WJC_METTL3_WT_vs_EV_F03.18842.18842.2 1.28E-05 18-Sep R.FEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1252.6088 11.45 23920 18842 2 1252.608847 627.3117 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3617 - 4.36E+06 - - - 0.0359 - 1.983 0.55 - 261.9 1 2 0 0 10 0 0 0 7.96E+08 6.96E+07 - - - 5.0142 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18846.18846.2 0.0212 18-Oct R.FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1262.6171 11.45 23924 18846 2 1262.617629 632.3158 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3617.5 - 418790 - - - 0.4411 - 2.034 0.355 - 377.4 1 2 0 0.0006 10 0 0 0 7.96E+08 6.96E+07 - - - 3.6447 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18851.18851.2 0.00172 18-Oct R.FLLQDTVELR.E "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1232.6765 1.9 23928 18851 2 1232.677129 617.3455 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3618.1 - 1.41E+07 - - - 0.52 - 2.21 0.369 - 392.1 1 2 0 0.0006 10 0 0 0 1.77E+08 9.32E+07 - - - 3.9797 1 230117_WJC_METTL3_WT_vs_EV_F03.18854.18854.2 6.17E-05 24-Nov K.AEPLLGAPGELLK.Q sp|P17482|HXB9_HUMAN 1 1306.7497 2.56 23930 18854 2 1306.748774 654.3821 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 3618.4 - 1.29E+06 - - - -0.6727 - 2.124 0.522 - 307.8 1 2 0 -0.0009 13 0 0 0 2.03E+07 7.95E+06 - - - 4.8296 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18855.18855.2 0.00508 18-Dec K.IEVIEIMTDR[166.11].G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1227.6408 0.86 23931 18855 2 1227.642354 614.8277 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3618.4 - 2.46E+06 - - - 1.23 - 2.56 0.382 - 642.9 1 2 0 0.0015 10 0 0 0 1.58E+08 1.83E+08 - - - 4.4858 0.8734 230117_WJC_METTL3_WT_vs_EV_F03.18856.18856.2 9.33 12-May R.VLFLIPK.N "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q5JV98|Q5JV98_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|H0Y630|H0Y630_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 13 828.5473 2.13 23932 18856 2 828.547529 415.2809 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 8.72 3618.5 - 2.13E+06 - - - 0.2619 - 0.919 0.041 - 90.8 2 2 0 0.0002 7 0 0 0 3.45E+07 1.62E+07 - - - -1.0584 0.9008 230117_WJC_METTL3_WT_vs_EV_F03.18857.18857.2 1.59 22-Aug R.QVVNGLMLGQAR[166.11].L tr|H0YHV6|H0YHV6_HUMAN 1 1294.7055 0.04 23933 18857 2 1294.710804 648.36 WD repeat-containing protein 90 (Fragment) OS=Homo sapiens OX=9606 GN=WDR90 PE=4 SV=1 9.75 3618.6 - 2.01E+06 - - - 4.089 - 1.162 0.045 - 84.4 1 2 0 0.0053 12 0 0 0 9.89E+05 2.52E+07 - - - -0.2332 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18858.18858.2 0.00491 14-Aug R.DFVNYLVR.L sp|Q08211|DHX9_HUMAN 1 1024.5342 0.87 23934 18858 2 1024.534753 513.2744 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.84 3618.6 - 1.90E+06 - - - 0.5583 - 1.745 0.336 - 284.9 1 2 0 0.0006 8 0 0 0 3.20E+08 3.67E+08 - - - 3.2017 0.9962 230117_WJC_METTL3_WT_vs_EV_F03.18860.18860.2 0.0699 16-Aug R.NLILSAFPR.N sp|A5YKK6|CNOT1_HUMAN 1 1029.5971 11.31 23936 18860 2 1029.600737 515.8058 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 9.75 3618.8 - 921548 - - - 3.5179 - 1.582 0.22 - 185.7 1 2 0 0.0036 9 0 0 0 1.58E+07 1.39E+06 - - - 1.9918 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18861.18861.2 0.000182 20-Dec R.LAVDLSEVVIK.W "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1184.7016 0.24 23937 18861 2 1184.70221 593.3581 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.37 3618.9 - 863278 - - - 0.4811 - 2.344 0.335 - 364.8 1 2 0 0.0006 11 0 0 0 1.74E+07 7.34E+07 - - - 3.8196 0.999 230117_WJC_METTL3_WT_vs_EV_F03.18871.18871.2 0.00491 18-Nov K.IEVIEIMTDR.G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1217.6326 0.86 23943 18871 2 1217.631066 609.8236 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3620.2 - 858425 - - - -1.2385 - 2.389 0.334 - 503.4 1 2 0 -0.0015 10 0 0 0 1.58E+08 1.83E+08 - - - 3.9383 0.998 230117_WJC_METTL3_WT_vs_EV_F03.18872.18872.2 0.631 24-Dec K.AEPLLGAPGELLK[136.11].Q sp|P17482|HXB9_HUMAN 1 1314.7639 2.73 23944 18872 2 1314.76201 658.3892 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 3620.3 - 140446 - - - -1.4018 - 1.98 0.305 - 336.5 1 2 0 -0.0018 13 0 0 0 2.03E+07 7.44E+06 - - - 3.0463 0.9709 230117_WJC_METTL3_WT_vs_EV_F03.18876.18876.2 3.71 14-May R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 1.03 23948 18876 2 898.522849 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 3620.7 - 142317 - - - -0.8536 - 1.225 0.141 - 44.2 6 2 0 -0.0008 8 0 0 0 1.15E+07 1.12E+07 - - - 0.3466 0.997 230117_WJC_METTL3_WT_vs_EV_F03.18877.18877.3 0.034 Sep-40 K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 0.92 23949 18877 3 1197.720915 400.2477 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3620.9 - 99650 - - - -0.288 - 1.94 0.203 - 78.5 1 2 0 -0.0003 11 0 0 0 4.11E+06 4.47E+06 - - - 2.6857 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18881.18881.2 5.37E-05 20-Dec K.TPPPVLIFAEK.K sp|Q9UJV9|DDX41_HUMAN 1 1210.6962 1.63 23951 18881 2 1210.695439 606.3554 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3621.4 - 1.62E+06 - - - -0.5964 - 2.024 0.464 - 406.6 1 2 0 -0.0007 11 0 0 0 1.07E+08 6.58E+07 - - - 4.3753 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18883.18883.2 0.522 16-Sep R.VEFILEQMR.L sp|O00232|PSD12_HUMAN 1 1163.6009 1.99 23953 18883 2 1163.602707 582.8077 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.53 3621.6 - 727919 - - - 1.5701 - 2.035 0.393 - 446.2 1 2 0 0.0018 9 0 0 0 1.45E+07 7.26E+06 - - - 3.9986 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18884.18884.2 0.153 14-Oct R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 3.89 23954 18884 2 1000.560966 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3621.7 - 341487 - - - 1.6321 - 2.164 0.222 - 315.6 1 2 0 0.0016 8 0 0 0 1.55E+07 3.99E+06 - - - 3.0084 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.18892.18892.2 0.00699 14-Jul R.DFVNYLVR[166.11].L sp|Q08211|DHX9_HUMAN 1 1034.5425 0.87 23960 18892 2 1034.544228 518.2785 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.84 3622.7 - 3.44E+07 - - - 1.7177 - 1.452 0.363 - 194.9 1 2 0 0.0018 8 0 0 0 3.20E+08 3.67E+08 - - - 2.8463 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18893.18893.2 0.000624 20-Dec R.IGFVGFPSVGK.S sp|Q9Y295|DRG1_HUMAN 1 1106.6124 1.8 23961 18893 2 1106.613511 554.3135 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 8.75 3622.8 - 4.20E+06 - - - 0.976 - 2.036 0.444 - 403.1 1 2 0 0.0011 11 0 0 0 7.02E+07 3.89E+07 - - - 4.2434 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.18894.18894.2 0.0389 20-Aug R.ILLLGLDNAGK.T "sp|P36405|ARL3_HUMAN,sp|Q13795|ARFRP_HUMAN" 2 1125.6758 1.18 23962 18894 2 1125.67775 563.8452 ADP-ribosylation factor-like protein 3 OS=Homo sapiens OX=9606 GN=ARL3 PE=1 SV=2 5.84 3622.9 - 1.51E+06 - - - 1.7678 - 1.701 0.24 - 128.1 1 2 0 0.002 11 0 0 0 1.77E+07 1.50E+07 - - - 2.2501 0.998 230117_WJC_METTL3_WT_vs_EV_F03.18895.18895.2 0.138 14-Aug R.DLTDYLMK[136.11].L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 1005.4932 1.08 23963 18895 2 1005.494099 503.7539 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3623 - 885756 - - - 0.8603 - 1.316 0.254 - 195.4 1 2 0 0.0009 8 0 0 0 5.38E+07 4.97E+07 - - - 1.7449 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18897.18897.2 0.00522 14-Aug R.DLTDYLMK.L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 997.479 1.08 23965 18897 2 997.479818 499.7468 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3623.3 - 840634 - - - 0.786 - 1.523 0.367 - 198 1 2 0 0.0008 8 0 0 0 5.38E+07 4.97E+07 - - - 3.0202 0.9962 230117_WJC_METTL3_WT_vs_EV_F03.18900.18900.2 8.84E-05 20-Sep R.YLLEQDFPGMR.L "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN" 2 1367.6544 3.03 23968 18900 2 1367.661448 684.8345 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.37 3623.7 - 353131 - - - 5.1738 - 1.851 0.348 - 292.6 1 2 0 0.0071 11 0 0 0 3.18E+06 1.05E+06 - - - 3.2748 1 230117_WJC_METTL3_WT_vs_EV_F03.18902.18902.2 1.21E-06 20-Nov K.NAVEEYVYEFR.D "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1417.6514 0.72 23970 18902 2 1417.652095 709.833 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.25 3623.9 - 160568 - - - 0.4938 - 2.457 0.557 - 753.9 1 2 0 0.0007 11 0 0 0 1.34E+06 1.85E+06 - - - 5.5866 0.99 230117_WJC_METTL3_WT_vs_EV_F03.18915.18915.2 0.0699 16-Jul K.ITPLMAAFR.K "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1018.5634 2.49 23980 18915 2 1018.565291 510.289 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 9.75 3625.2 - 299855 - - - 1.884 - 1.445 0.056 - 141.5 1 2 0 0.0019 9 0 0 0 1.16E+07 4.65E+06 - - - 0.519 0.8558 230117_WJC_METTL3_WT_vs_EV_F03.18916.18916.2 0.648 14-Jul S.GVISLSGR[166.11].L "sp|Q8TDW7|FAT3_HUMAN,sp|Q96II8|LRCH3_HUMAN,tr|E9PQ73|E9PQ73_HUMAN,tr|E9PD99|E9PD99_HUMAN,tr|F8WFB5|F8WFB5_HUMAN" 5 797.4635 7.52 23981 18916 2 797.465449 399.739 Protocadherin Fat 3 OS=Homo sapiens OX=9606 GN=FAT3 PE=2 SV=3 9.75 3625.4 - 247236 - - - 2.4791 - 1.472 0.236 - 157.1 1 1 0 0.002 8 0 0 0 2.79E+07 3.71E+06 - - - 1.9495 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18919.18919.2 0.00803 20-Nov R.IGFVGFPSVGK[136.11].S sp|Q9Y295|DRG1_HUMAN 1 1114.6266 1.82 23983 18919 2 1114.628306 558.3206 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 8.75 3625.7 - 2.83E+06 - - - 1.5027 - 1.895 0.35 - 308.9 1 2 0 0.0017 11 0 0 0 7.02E+07 3.86E+07 - - - 3.3548 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.18920.18920.2 0.0423 12-May K.DYVDLFR.H sp|P78527|PRKDC_HUMAN 1 926.4498 0.37 23984 18920 2 926.450914 464.2322 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.21 3625.8 - 888625 - - - 1.2219 - 1.097 0.318 - 103.3 1 2 0 0.0011 7 0 0 0 1.40E+07 3.77E+07 - - - 1.6827 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.18922.18922.2 0.000192 22-Dec K.IIENELEGFGIR[166.11].L sp|Q9Y295|DRG1_HUMAN 1 1398.7383 1.35 23986 18922 2 1398.734091 700.3764 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3626.1 - 570090 - - - -2.9734 - 2.229 0.462 - 337.9 1 2 0 -0.0042 12 0 0 0 1.11E+07 8.25E+06 - - - 4.561 0.999 230117_WJC_METTL3_WT_vs_EV_F03.18924.18924.2 5.54E-05 16-Oct K.LYDPLLEYR.R "sp|Q13614|MTMR2_HUMAN,tr|A0A6Q8PHS7|A0A6Q8PHS7_HUMAN,tr|C9JEX3|C9JEX3_HUMAN,tr|A0A6Q8PGS5|A0A6Q8PGS5_HUMAN,tr|A0A6Q8PGV9|A0A6Q8PGV9_HUMAN" 5 1180.6128 0.48 23988 18924 2 1180.613855 591.3137 Myotubularin-related protein 2 OS=Homo sapiens OX=9606 GN=MTMR2 PE=1 SV=4 4.37 3626.3 - 264198 - - - 0.8724 - 1.756 0.246 - 314.8 1 2 0 0.001 9 0 0 0 2.86E+06 5.91E+06 - - - 2.4865 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.18930.18930.2 0.00198 16-Sep K.GLDFALLQK[136.11].V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1011.5844 1.24 23992 18930 2 1011.588965 506.7995 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3627 - 1.30E+06 - - - 4.4811 - 1.871 0.438 - 213.8 1 2 0 0.0045 9 0 0 0 3.65E+07 2.95E+07 - - - 4.0871 0.8747 230117_WJC_METTL3_WT_vs_EV_F03.18932.18932.2 0.019 16-Jun K.ILVTPWDYR.L sp|Q8TF46|DI3L1_HUMAN 1 1161.6182 0.19 23994 18932 2 1161.62474 581.8164 DIS3-like exonuclease 1 OS=Homo sapiens OX=9606 GN=DIS3L PE=1 SV=2 5.84 3627.3 - 396484 - - - 5.5913 - 1.279 0.07 - 107.9 1 2 0 0.0065 9 0 0 0 3.13E+06 1.65E+07 - - - 0.2679 0.998 230117_WJC_METTL3_WT_vs_EV_F03.18935.18935.2 0.00185 20-Sep R.LMMDPLTGLNR[166.11].G "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1269.6449 0.84 23997 18935 2 1269.642638 635.8297 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.84 3627.7 - 306837 - - - -1.769 - 1.698 0.392 - 270.2 1 2 0 -0.0022 11 0 0 0 1.31E+07 1.57E+07 - - - 3.3679 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18936.18936.2 0.000101 24-Dec R.ILLAEVPTMAVEK[136.11].V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1420.8091 6.27 23998 18936 2 1420.812066 711.4118 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3627.8 - 264022 - - - 2.0953 - 2.211 0.473 - 427.6 1 2 0 0.003 13 0 0 0 3.29E+07 5.25E+06 - - - 4.57 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.18937.18937.2 0.00207 22-Aug K.YMGAAAMYLISK.R "sp|Q9H7Z7|PGES2_HUMAN,tr|A0A7I2V5T7|A0A7I2V5T7_HUMAN,tr|A6NHH0|A6NHH0_HUMAN,tr|X6RJ95|X6RJ95_HUMAN,tr|A0A7I2V5X6|A0A7I2V5X6_HUMAN" 5 1317.6461 2.47 23999 18937 2 1317.651257 659.8303 Prostaglandin E synthase 2 OS=Homo sapiens OX=9606 GN=PTGES2 PE=1 SV=1 8.5 3627.9 - 244030 - - - 3.9017 - 1.473 0.332 - 86.3 1 2 0 0.0051 12 0 0 0 3.84E+06 1.56E+06 - - - 2.5106 1 230117_WJC_METTL3_WT_vs_EV_F03.18942.18942.2 8.25E-05 24-Dec R.LDYLGVSYGLTPR[166.11].L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1462.7695 0.92 24004 18942 2 1462.77736 732.3921 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.83 3628.6 - 143665 - - - 5.3392 - 2.333 0.508 - 289.5 1 2 0 0.0078 13 0 0 0 4.56E+06 4.98E+06 - - - 4.9649 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.18945.18945.2 4.88E-05 16-Sep K.GFGFVSFER.H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1044.5029 0.98 24005 18945 2 1044.507459 523.2587 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3629 - 6.99E+06 - - - 4.3829 - 1.738 0.437 - 307.1 1 2 0 0.0046 9 0 0 0 4.06E+08 4.14E+08 - - - 3.8663 1 230117_WJC_METTL3_WT_vs_EV_F03.18946.18946.2 1.59E-06 22-Dec K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 1.92 24006 18946 2 1263.696208 632.853 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3629.1 - 2.28E+06 - - - 3.7921 - 2.531 0.593 - 338.1 1 2 0 0.0048 12 0 0 0 1.65E+07 8.57E+06 - - - 5.8627 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.18947.18947.2 2.43E-06 22-Dec K.IIENELEGFGIR.L sp|Q9Y295|DRG1_HUMAN 1 1388.73 1.35 24007 18947 2 1388.732249 695.3723 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3629.1 - 2.61E+06 - - - 1.6339 - 2.377 0.379 - 472.3 1 2 0 0.0023 12 0 0 0 1.11E+07 8.25E+06 - - - 4.1178 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.18948.18948.2 0.0111 14-Sep K.IDILTELR[166.11].D "sp|O00139|KIF2A_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 981.5734 1.11 24008 18948 2 981.575692 491.794 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.37 3629.2 - 2.23E+06 - - - 2.3177 - 2.059 0.314 - 271.2 1 2 0 0.0023 8 0 0 0 4.08E+07 3.67E+07 - - - 3.5377 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18949.18949.2 0.0882 18-Sep K.LEPAFLSGLR.C "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1101.6182 1.27 24009 18949 2 1101.620514 551.8164 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3629.3 - 1.96E+06 - - - 2.0597 - 1.932 0.31 - 229 1 2 0 0.0023 10 0 0 0 7.97E+06 6.27E+06 - - - 3.1682 0.9959 230117_WJC_METTL3_WT_vs_EV_F03.18953.18953.2 2.31E-05 26-Sep K.LNLVDLAGSENIGR.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1469.7838 0.02 24013 18953 2 1469.77886 735.8992 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 3629.7 - 367754 - - - -3.3658 - 1.811 0.452 - 238.5 1 2 0 -0.0049 14 0 0 0 1.06E+06 5.32E+07 - - - 3.8682 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18954.18954.2 0.000293 18-Oct K.C[160.03]LEEFELLGK.A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1236.606 1.03 24014 18954 2 1236.606184 619.3103 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3629.9 - 325136 - - - 0.1286 - 1.738 0.476 - 286.1 1 2 0 0.0002 10 0 0 0 6.80E+06 6.58E+06 - - - 4.0995 1 230117_WJC_METTL3_WT_vs_EV_F03.18955.18955.2 1.42E-06 26-Nov R.PVELGFAESAPAWR.L "sp|Q16342|PDCD2_HUMAN,tr|J3QK82|J3QK82_HUMAN,tr|F5GWT2|F5GWT2_HUMAN,tr|A0A087WYJ3|A0A087WYJ3_HUMAN,tr|F5H4V9|F5H4V9_HUMAN" 5 1528.7674 999 24015 18955 2 1528.773488 765.391 Programmed cell death protein 2 OS=Homo sapiens OX=9606 GN=PDCD2 PE=1 SV=2 4.53 3630 - 260698 - - - 3.964 - 2.492 0.526 - 326.7 1 1 0 0.0061 14 0 0 0 9.64E+05 0.00E+00 - - - 5.2155 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.18958.18958.2 0.584 18-Aug K.AIAINTFLPK[136.11].N sp|Q92615|LAR4B_HUMAN 1 1094.6579 1.22 24017 18958 2 1094.659875 548.3362 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3630.4 - 1.99E+06 - - - 1.7759 - 1.685 0.174 - 146.3 2 2 0 0.0019 10 0 0 0 4.28E+08 3.50E+08 - - - 1.6475 1 230117_WJC_METTL3_WT_vs_EV_F03.18959.18959.2 0.000119 15/24 R.ILLAEVPTMAVEK.V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1412.7949 6.27 24018 18959 2 1412.797507 707.4047 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3630.4 - 2.62E+06 - - - 1.8531 - 2.611 0.459 - 706.8 1 2 0 0.0026 13 0 0 0 3.29E+07 5.25E+06 - - - 4.8935 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.18960.18960.2 0.00133 16-Aug K.GLDFALLQK.V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1003.5702 1.19 24019 18960 2 1003.572464 502.7924 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3630.5 - 4.28E+06 - - - 2.2241 - 1.734 0.369 - 165.3 1 2 0 0.0022 9 0 0 0 3.58E+07 3.02E+07 - - - 3.3582 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.18961.18961.2 0.0507 20-Oct K.TPPPVLIFAEK[136.11].K sp|Q9UJV9|DDX41_HUMAN 1 1218.7104 1.62 24020 18961 2 1218.712705 610.3625 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3630.5 - 1.50E+06 - - - 1.9233 - 1.2 0.346 - 240.7 1 2 0 0.0023 11 0 0 0 1.07E+08 6.58E+07 - - - 2.089 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18962.18962.2 7.98E-05 22-Sep K.NIEDVIAQGIGK.L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1255.6772 1.98 24021 18962 2 1255.679539 628.8459 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3630.6 - 1.39E+06 - - - 1.85 - 1.79 0.438 - 151.9 1 2 0 0.0023 12 0 0 0 1.70E+07 8.57E+06 - - - 3.8072 0.9858 230117_WJC_METTL3_WT_vs_EV_F03.18964.18964.2 2.45 16-Oct K.LTQILSYLR[166.11].Q sp|Q13123|RED_HUMAN 1 1115.6578 1.44 24023 18964 2 1115.666025 558.8362 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3630.7 - 755915 - - - 7.3589 - 2.097 0.297 - 377.1 1 2 0 0.0082 9 0 0 0 5.76E+07 4.00E+07 - - - 3.3744 1 230117_WJC_METTL3_WT_vs_EV_F03.18965.18965.2 4.34E-07 16/20 M.PPYTVVYFPVR.G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1336.718 1.16 24024 18965 2 1336.719044 669.3663 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3630.9 - 658342 - - - 0.8117 - 2.992 0.537 - 1349.4 1 2 0 0.0011 11 0 0 0 6.13E+07 5.30E+07 - - - 5.9717 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.18966.18966.2 0.00293 14-Sep R.ITNWLVLK.N "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN,tr|H3BRT3|H3BRT3_HUMAN" 3 985.5961 2.01 24025 18966 2 985.600483 493.8053 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 8.75 3631 - 577269 - - - 4.4947 - 1.748 0.231 - 155.8 1 2 0 0.0044 8 0 0 0 5.82E+06 2.90E+06 - - - 2.4301 1 230117_WJC_METTL3_WT_vs_EV_F03.18967.18967.2 2.11E-06 20-Nov K.MALDIEIATYR[166.11].K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1304.6674 1.39 24026 18967 2 1304.674687 653.341 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3631 - 450920 - - - 5.5907 - 2.532 0.504 - 475.2 1 2 0 0.0073 11 0 0 0 8.85E+07 6.37E+07 - - - 5.2744 0.987 230117_WJC_METTL3_WT_vs_EV_F03.18972.18972.2 1.33 12-Aug R.WLLELSK[136.11].K sp|P35573|GDE_HUMAN 1 895.5259 0.6 24031 18972 2 895.524024 448.7702 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 6 3631.7 - 213289 - - - -2.0435 - 1.49 0.166 - 178.3 1 2 0 -0.0018 7 0 0 0 1.05E+07 1.74E+07 - - - 1.53 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.18973.18973.3 0.00193 Oct-36 R.DFLLK[136.11]PELLR[166.11].A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1260.7561 1.14 24032 18973 3 1260.75881 421.2593 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3631.8 - 201948 - - - 2.1662 - 2.132 0.412 - 122.5 1 2 0 0.0027 10 0 0 0 1.83E+07 1.60E+07 - - - 5.3436 0.997 230117_WJC_METTL3_WT_vs_EV_F03.18974.18974.2 0.0841 12-May K.LGDLFFR.V "sp|Q70EL1|UBP54_HUMAN,tr|H7C1E9|H7C1E9_HUMAN,tr|A0A7P0T9N2|A0A7P0T9N2_HUMAN,tr|A0A7P0T9K1|A0A7P0T9K1_HUMAN,tr|A0A804D9U3|A0A804D9U3_HUMAN" 5 866.465 1.19 24033 18974 2 866.466068 434.2398 Inactive ubiquitin carboxyl-terminal hydrolase 54 OS=Homo sapiens OX=9606 GN=USP54 PE=1 SV=4 5.84 3631.9 - 110512 - - - 1.1887 - 1.408 0.187 - 51.5 2 2 0 0.001 7 0 0 0 1.38E+06 1.16E+06 - - - 1.3716 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.18976.18976.2 0.0497 18-Jul K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.2 24034 18976 2 1086.645609 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3632.2 - 2.24E+06 - - - 1.7283 - 1.402 0.215 - 133.9 1 2 0 0.0019 10 0 0 0 3.67E+08 3.07E+08 - - - 1.5716 1 230117_WJC_METTL3_WT_vs_EV_F03.18978.18978.2 0.000617 16-Nov K.LTQILSYLR.Q sp|Q13123|RED_HUMAN 1 1105.6495 1.46 24036 18978 2 1105.651852 553.832 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3632.3 - 3.61E+06 - - - 2.0866 - 2.333 0.442 - 588.5 1 2 0 0.0023 9 0 0 0 5.85E+07 4.02E+07 - - - 4.7558 1 230117_WJC_METTL3_WT_vs_EV_F03.18979.18979.2 2.88E-07 15/20 M.PPYTVVYFPVR[166.11].G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1346.7262 1.17 24037 18979 2 1346.729902 674.3704 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3632.3 - 3.57E+06 - - - 2.7274 - 3.068 0.527 - 1322.9 1 2 0 0.0037 11 0 0 0 6.13E+07 5.24E+07 - - - 5.9649 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.18981.18981.2 0.242 18-Aug K.LLLGDLAPVR.G sp|Q9NUQ8|ABCF3_HUMAN 1 1065.6546 3.45 24039 18981 2 1065.65611 533.8346 ATP-binding cassette sub-family F member 3 OS=Homo sapiens OX=9606 GN=ABCF3 PE=1 SV=2 5.84 3632.4 - 1.26E+06 - - - 1.3888 - 1.779 0.218 - 171.4 1 2 0 0.0015 10 0 0 0 7.69E+06 2.23E+06 - - - 2.2586 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.18982.18982.2 0.379 16-Jun R.LLIDEAILK.C "sp|P49591|SYSC_HUMAN,tr|Q5T5C7|Q5T5C7_HUMAN" 2 1026.6325 1.74 24040 18982 2 1026.633795 514.3235 "Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3" 4.37 3632.4 - 1.23E+06 - - - 1.2634 - 1.395 0.215 - 86.5 1 2 0 0.0013 9 0 0 0 9.12E+06 5.23E+06 - - - 1.5917 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.18983.18983.2 0.00114 20-Aug R.TVPILFASTVR.R sp|Q6P1M0|S27A4_HUMAN 1 1202.7023 0.36 24041 18983 2 1202.707105 602.3584 Long-chain fatty acid transport protein 4 OS=Homo sapiens OX=9606 GN=SLC27A4 PE=1 SV=1 9.41 3632.5 - 1.14E+06 - - - 3.9877 - 1.604 0.45 - 201.5 1 2 0 0.0048 11 0 0 0 8.29E+06 2.31E+07 - - - 3.6414 0.973 230117_WJC_METTL3_WT_vs_EV_F03.18985.18985.2 0.00558 16-Jul R.SPTWFGIPR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1069.5584 0.97 24043 18985 2 1069.563759 535.7865 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3632.6 - 694153 - - - 4.9778 - 1.387 0.157 - 137.3 1 2 0 0.0053 9 0 0 0 5.08E+08 5.21E+08 - - - 1.1454 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.18988.18988.2 0.00146 20-Nov R.LEPLVNDLTLR.L sp|Q70UQ0|IKIP_HUMAN 1 1281.7293 1.82 24046 18988 2 1281.731869 641.8719 Inhibitor of nuclear factor kappa-B kinase-interacting protein OS=Homo sapiens OX=9606 GN=IKBIP PE=1 SV=1 4.37 3633 - 458200 - - - 2.0418 - 1.998 0.388 - 509.4 1 2 0 0.0026 11 0 0 0 1.06E+07 5.82E+06 - - - 3.7784 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.18994.18994.2 0.191 14-Jul R.FYTIEILK.V sp|P12273|PIP_HUMAN 1 1025.5797 70.56 24050 18994 2 1025.581554 513.7971 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 6 3633.7 - 3.10E+06 - - - 1.7746 - 1.457 0.223 - 111.2 1 2 0 0.0018 8 0 0 0 2.35E+08 3.33E+06 - - - 1.8226 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.18995.18995.2 0.611 14-Jun K.LLQQLFLK[136.11].A sp|Q9P287|BCCIP_HUMAN 1 1009.6416 1.29 24051 18995 2 1009.643608 505.8281 BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1 8.75 3633.7 - 1.83E+06 - - - 2.0354 - 1.342 0.254 - 73.6 2 2 0 0.0021 8 0 0 0 1.46E+07 1.13E+07 - - - 1.6691 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.18996.18996.3 0.000467 Oct-36 R.DFLLKPELLR.A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1242.7336 1.14 24052 18996 3 1242.734941 415.2518 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3633.8 - 2.01E+06 - - - 1.0718 - 1.994 0.402 - 122 1 2 0 0.0013 10 0 0 0 1.83E+07 1.60E+07 - - - 5.0371 1 230117_WJC_METTL3_WT_vs_EV_F03.18997.18997.2 1.15E-06 18-Oct K.GIFLGDDEWR.E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1206.5669 1.65 24053 18997 2 1206.568832 604.2907 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3633.9 - 1.49E+06 - - - 1.5706 - 2.222 0.581 - 338.4 1 2 0 0.0019 10 0 0 0 2.30E+07 1.39E+07 - - - 5.5603 0.9956 230117_WJC_METTL3_WT_vs_EV_F03.18998.18998.2 0.0196 16-Sep R.LLIDEAILK[136.11].C "sp|P49591|SYSC_HUMAN,tr|Q5T5C7|Q5T5C7_HUMAN" 2 1034.6467 1.66 24054 18998 2 1034.649146 518.3306 "Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3" 4.37 3633.9 - 1.05E+06 - - - 2.366 - 1.506 0.142 - 182 1 2 0 0.0024 9 0 0 0 8.66E+06 5.23E+06 - - - 1.2736 1 230117_WJC_METTL3_WT_vs_EV_F03.18999.18999.2 3.58E-06 18-Oct K.GIFLGDDEWR[166.11].E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1216.5752 1.65 24055 18999 2 1216.577272 609.2949 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3634 - 998127 - - - 1.6974 - 2.009 0.572 - 338.8 1 2 0 0.0021 10 0 0 0 2.30E+07 1.39E+07 - - - 5.2125 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19003.19003.2 0.0432 18-Sep R.LLLDTLQLSK.- "sp|O15357|SHIP2_HUMAN,tr|H7BXR2|H7BXR2_HUMAN" 2 1142.6911 2.53 24059 19003 2 1142.692459 572.3528 "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 OS=Homo sapiens OX=9606 GN=INPPL1 PE=1 SV=2" 5.84 3634.5 - 389770 - - - 1.2112 - 1.951 0.385 - 176 1 2 0 0.0014 10 0 0 0 3.72E+06 1.47E+06 - - - 3.7497 0.9939 230117_WJC_METTL3_WT_vs_EV_F03.19005.19005.3 0.117 Jul-36 K.SAEFLLHMLK[136.11].N "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 1195.6515 0.84 24061 19005 3 1195.65364 399.5578 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 6.47 3634.7 - 236614 - - - 1.8183 - 1.493 0.191 - 58.2 1 2 0 0.0022 10 0 0 0 8.05E+05 9.55E+05 - - - 1.8393 0.9826 230117_WJC_METTL3_WT_vs_EV_F03.19008.19008.2 0.346 24-Apr R.LLPPEDTQELIFK[136.11].D sp|O60287|NPA1P_HUMAN 1 1549.8483 1.43 24064 19008 2 1549.850675 775.9314 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 4.14 3635.1 - 127848 - - - 1.5253 - 1.187 0.158 - 36.2 17 2 0 0.0024 13 0 0 0 2.65E+06 1.86E+06 - - - 0.0976 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19011.19011.2 3.64E-06 18-Nov K.C[160.03]LEEFELLGK[136.11].A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1244.6202 1.03 24066 19011 2 1244.619967 623.3174 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3635.5 - 447017 - - - -0.2073 - 1.838 0.493 - 353.7 1 2 0 -0.0003 10 0 0 0 6.80E+06 6.58E+06 - - - 4.3812 0.999 230117_WJC_METTL3_WT_vs_EV_F03.19013.19013.2 0.017 12-Jun R.EYLYFLK.H sp|Q8N1N4|K2C78_HUMAN 1 974.5113 22.39 24067 19013 2 974.512149 488.2629 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 6.1 3635.7 - 1.16E+06 - - - 0.8507 - 1.244 0.363 - 144 1 2 0 0.0008 7 0 0 0 2.65E+07 1.18E+06 - - - 2.4137 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19014.19014.2 0.00175 16-Jul K.VQWGVFVPR[166.11].D sp|Q8IWA0|WDR75_HUMAN 1 1096.6057 1.48 24068 19014 2 1096.606756 549.3101 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 9.72 3635.8 - 554633 - - - 0.9447 - 1.472 0.359 - 227.1 1 2 0 0.001 9 0 0 0 1.56E+07 1.06E+07 - - - 2.8108 0.991 230117_WJC_METTL3_WT_vs_EV_F03.19015.19015.2 0.137 16-Jun K.VQWGVFVPR.D sp|Q8IWA0|WDR75_HUMAN 1 1086.5974 1.41 24069 19015 2 1086.599141 544.306 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 9.72 3635.8 - 755216 - - - 1.5562 - 1.286 0.106 - 111.5 1 2 0 0.0017 9 0 0 0 1.46E+07 1.03E+07 - - - 0.5511 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.19016.19016.2 0.0526 14-Aug K.LLQQLFLK.A sp|Q9P287|BCCIP_HUMAN 1 1001.6274 1.29 24070 19016 2 1001.628397 501.821 BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1 8.75 3635.9 - 455897 - - - 1.0423 - 1.68 0.273 - 165.8 1 2 0 0.001 8 0 0 0 1.46E+07 1.13E+07 - - - 2.6217 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19023.19023.2 0.00131 14-Sep R.LSFAVPFR[166.11].E sp|P78527|PRKDC_HUMAN 1 945.5312 1.14 24075 19023 2 945.533401 473.7729 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3636.6 - 1.41E+06 - - - 2.3722 - 1.885 0.322 - 305.6 1 2 0 0.0022 8 0 0 0 2.07E+07 1.82E+07 - - - 3.3305 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19024.19024.2 0.245 14-Aug R.LSFAVPFR.E sp|P78527|PRKDC_HUMAN 1 935.5229 1.14 24076 19024 2 935.524561 468.7687 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3636.8 - 1.21E+06 - - - 1.7883 - 1.987 0.262 - 191 1 2 0 0.0017 8 0 0 0 2.07E+07 1.82E+07 - - - 3.0464 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19025.19025.2 0.00439 16-Oct K.ASSLISLLK.Q "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 930.575 2.72 24077 19025 2 930.576879 466.2948 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.8 3636.9 - 1.18E+06 - - - 2.0375 - 2.116 0.416 - 414.1 1 2 0 0.0019 9 0 0 0 2.34E+07 8.62E+06 - - - 4.2814 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.19026.19026.2 0.000757 20-Oct R.FLMSLVNQVPK.L "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 1274.7057 1.13 24078 19026 2 1274.709648 638.3601 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 8.75 3637 - 1.03E+06 - - - 3.1129 - 1.706 0.175 - 250 1 2 0 0.004 11 0 0 0 3.18E+07 2.81E+07 - - - 1.7773 0.9641 230117_WJC_METTL3_WT_vs_EV_F03.19028.19028.2 0.00241 14-Sep K.LGTLFAFK[136.11].K sp|Q6F5E8|CARL2_HUMAN 1 903.5309 4.95 24080 19028 2 903.538836 452.7727 "Capping protein, Arp2\3 and myosin-I linker protein 2 OS=Homo sapiens OX=9606 GN=CARMIL2 PE=1 SV=2" 8.75 3637.2 - 561206 - - - 8.739 - 1.682 0.295 - 170.2 1 2 0 0.0079 8 0 0 0 1.77E+07 3.57E+06 - - - 2.7856 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19029.19029.2 0.014 18-Sep R.DFLLKPELLR.A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1242.7336 1.93 24081 19029 2 1242.735503 622.3741 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3637.3 - 555911 - - - 1.5241 - 1.817 0.288 - 369.5 1 2 0 0.0019 10 0 0 0 5.22E+06 2.71E+06 - - - 2.8345 1 230117_WJC_METTL3_WT_vs_EV_F03.19033.19033.2 3.13E-07 13/26 R.FIAVGYVDDTQFVR.F "sp|P04439|HLAA_HUMAN,tr|A0A140T953|A0A140T953_HUMAN,tr|A0A140T941|A0A140T941_HUMAN,tr|A0A1W2PQS8|A0A1W2PQS8_HUMAN,tr|A0A0G2JI36|A0A0G2JI36_HUMAN,tr|A0A140T8W8|A0A140T8W8_HUMAN,tr|Q9GJ45|Q9GJ45_HUMAN,tr|Q53Z42|Q53Z42_HUMAN,tr|Q5RJ27|Q5RJ27_HUMAN,tr|Q53YP1|Q53YP1_HUMAN,tr|Q5SRN5|Q5SRN5_HUMAN,tr|A0A1W2PS24|A0A1W2PS24_HUMAN,tr|A0A0G2JIF2|A0A0G2JIF2_HUMAN,tr|A0A1W2PQD0|A0A1W2PQD0_HUMAN,tr|A0A1W2PRZ0|A0A1W2PRZ0_HUMAN,tr|A0A140T9U0|A0A140T9U0_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A0G2JPD3|A0A0G2JPD3_HUMAN,tr|A0A140T9W2|A0A140T9W2_HUMAN,tr|O78179|O78179_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|A0A1W2PPQ2|A0A1W2PPQ2_HUMAN,tr|A0A140T9T1|A0A140T9T1_HUMAN,tr|Q5SPM2|Q5SPM2_HUMAN,tr|Q5SUL5|Q5SUL5_HUMAN,tr|A0A140T8Y4|A0A140T8Y4_HUMAN,tr|A0A140T975|A0A140T975_HUMAN,tr|A0A140TA03|A0A140TA03_HUMAN,tr|A0A140TA13|A0A140TA13_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A1W2PSE7|A0A1W2PSE7_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|A0A1W2PPF8|A0A1W2PPF8_HUMAN,tr|D9J307|D9J307_HUMAN,tr|A0A140T937|A0A140T937_HUMAN,tr|Q5SRN7|Q5SRN7_HUMAN,tr|A0A1W2PR61|A0A1W2PR61_HUMAN,tr|A0A140T912|A0A140T912_HUMAN,tr|A0A140T9M0|A0A140T9M0_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN,tr|A0A1W2PS39|A0A1W2PS39_HUMAN,tr|A0A140T9Z6|A0A140T9Z6_HUMAN,tr|A0A140T9M5|A0A140T9M5_HUMAN,tr|A0A140T930|A0A140T930_HUMAN,tr|A0A140T9Z4|A0A140T9Z4_HUMAN,tr|B0UXQ0|B0UXQ0_HUMAN,tr|A0A0G2JL56|A0A0G2JL56_HUMAN" 48 1628.8199 8.33 24085 19033 2 1628.826161 815.4172 "HLA class I histocompatibility antigen, A alpha chain OS=Homo sapiens OX=9606 GN=HLA-A PE=1 SV=2" 4.21 3637.8 - 252717 - - - 3.8697 - 2.899 0.637 - 508.6 1 2 0 0.0063 14 0 0 0 2.71E+06 3.26E+05 - - - 6.4149 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19035.19035.3 0.00831 Sep-36 K.FLPFSFEHIR[166.11].E "sp|Q93050|VPP1_HUMAN,tr|F5H1T6|F5H1T6_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 4 1301.6796 1.2 24087 19035 3 1301.679656 434.9005 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 6.75 3638.1 - 210123 - - - 0.033 - 1.806 0.336 - 98.4 1 2 0 0 10 0 0 0 2.79E+06 2.33E+06 - - - 4.0124 1 230117_WJC_METTL3_WT_vs_EV_F03.19038.19038.2 9.94E-06 16-Oct K.VFDAIMNFK.K sp|P13639|EF2_HUMAN 1 1083.5423 4.01 24088 19038 2 1083.547153 542.7784 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.81 3638.5 - 4.27E+06 - - - 4.4761 - 1.826 0.533 - 247.8 1 2 0 0.0049 9 0 0 0 8.60E+07 2.15E+07 - - - 4.7182 1 230117_WJC_METTL3_WT_vs_EV_F03.19039.19039.2 6.83E-07 18-Dec R.LMALLGQALK[136.11].W sp|Q2TAY7|SMU1_HUMAN 1 1064.6507 0.96 24089 19039 2 1064.654023 533.3326 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.75 3638.6 - 1.37E+06 - - - 3.0865 - 2.382 0.57 - 540.9 1 2 0 0.0033 10 0 0 0 2.56E+07 2.67E+07 - - - 5.6727 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19040.19040.2 5.00E-06 16-Oct K.MC[160.03]LFAGFQR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1128.5209 0.89 24090 19040 2 1128.524377 565.2677 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3638.7 - 1.59E+06 - - - 3.12 - 2.068 0.358 - 617.9 1 2 0 0.0035 9 0 0 0 8.14E+07 9.09E+07 - - - 3.7861 0.997 230117_WJC_METTL3_WT_vs_EV_F03.19041.19041.2 2.27E-05 16-Oct K.IIDGLLVMR[166.11].K "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1038.6135 3.43 24091 19041 2 1038.617201 520.314 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.84 3638.8 - 1.01E+06 - - - 3.5567 - 2.05 0.154 - 263.5 1 2 0 0.0037 9 0 0 0 8.71E+07 2.54E+07 - - - 2.254 1 230117_WJC_METTL3_WT_vs_EV_F03.19042.19042.2 0.000229 16-Oct K.FALNSLLQR[166.11].Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1070.6112 2.32 24092 19042 2 1070.614242 536.3129 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.75 3638.9 - 907326 - - - 2.8423 - 2.031 0.479 - 408.4 1 2 0 0.003 9 0 0 0 2.87E+07 1.24E+07 - - - 4.6277 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.19047.19047.2 0.338 14-Jul R.IPLNDLFR.C sp|P13473|LAMP2_HUMAN 1 986.5549 7.19 24097 19047 2 986.555268 494.2847 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3639.6 - 367811 - - - 0.3568 - 1.724 0.288 - 201.8 1 2 0 0.0004 8 0 0 0 9.73E+07 1.35E+07 - - - 2.8107 0.9938 230117_WJC_METTL3_WT_vs_EV_F03.19048.19048.2 0.0159 22-Jul K.TPLPPELADVQA.- "sp|Q9Y5V0|ZN706_HUMAN,tr|H0YC70|H0YC70_HUMAN" 2 1249.6554 - 24098 19048 2 1249.659356 625.835 Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1 3.67 3639.7 - 240824 - - - 3.1513 - 1.386 0.197 - 119.3 1 2 0 0.0039 12 0 0 0 - - - - - 1.3537 0.9756 230117_WJC_METTL3_WT_vs_EV_F03.19050.19050.2 4.73E-06 24-Sep R.GFVPDTPVGVAHF.L "sp|Q6DN90|IQEC1_HUMAN,tr|A0A0C4DGT3|A0A0C4DGT3_HUMAN,tr|A0A2R8Y7T6|A0A2R8Y7T6_HUMAN,tr|A0A3B3IRZ4|A0A3B3IRZ4_HUMAN,tr|A0A2R8Y695|A0A2R8Y695_HUMAN,tr|A0A3B3IU98|A0A3B3IU98_HUMAN" 6 1341.6717 - 24100 19050 2 1341.673301 671.8431 IQ motif and SEC7 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=IQSEC1 PE=1 SV=1 5.08 3639.9 - 327111 - - - 1.1657 - 1.741 0.482 - 84.4 1 1 0 0.0016 13 0 0 0 - - - - - 4.0236 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.19059.19059.2 0.000361 16-Aug K.VFDAIMNFK[136.11].K sp|P13639|EF2_HUMAN 1 1091.5565 4.05 24107 19059 2 1091.559493 546.7855 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.81 3641.2 - 3.21E+06 - - - 2.7392 - 1.66 0.361 - 125.6 1 2 0 0.003 9 0 0 0 8.69E+07 2.15E+07 - - - 3.1727 0.9841 230117_WJC_METTL3_WT_vs_EV_F03.19062.19062.2 0.0425 16-Jul K.DIVENYFMR.D "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN" 2 1185.5488 1.34 24110 19062 2 1185.545914 593.7817 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.37 3641.4 - 947640 - - - -2.4723 - 1.233 0.263 - 141.2 1 2 0 -0.0029 9 0 0 0 8.18E+06 6.12E+06 - - - 1.5885 0.9927 230117_WJC_METTL3_WT_vs_EV_F03.19064.19064.2 0.000679 18-Aug K.TIC[160.03]AEFAILR[166.11].M "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1202.6357 1.14 24112 19064 2 1202.632891 602.3251 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.66 3641.5 - 670476 - - - -2.3349 - 1.484 0.284 - 194.4 1 2 0 -0.0028 10 0 0 0 9.80E+06 8.61E+06 - - - 2.2396 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.19066.19066.2 0.358 16-Sep K.GLSLGFLEK.K sp|Q9NU22|MDN1_HUMAN 1 962.5437 0.73 24114 19066 2 962.546803 482.2791 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6 3641.7 - 545913 - - - 3.2414 - 1.797 0.189 - 221 1 2 0 0.0031 9 0 0 0 6.71E+06 9.17E+06 - - - 2.1316 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19067.19067.3 0.000849 Sep-36 R.LFDQAFGLPR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1162.6135 1.17 24115 19067 3 1162.614309 388.5451 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3641.8 - 408993 - - - 0.701 - 1.77 0.289 - 88.4 1 2 0 0.0008 10 0 0 0 2.72E+06 2.33E+06 - - - 3.4293 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.19069.19069.2 0.0019 20-Nov K.GPILMELQTYR.Y "sp|P08559|ODPA_HUMAN,sp|P29803|ODPAT_HUMAN" 2 1319.6908 4.05 24117 19069 2 1319.696719 660.8527 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 6 3642.1 - 290596 - - - 4.517 - 1.821 0.443 - 146 1 2 0 0.006 11 0 0 0 5.80E+06 1.43E+06 - - - 3.9326 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19073.19073.2 1.90E-05 16-Sep K.MC[160.03]LFAGFQR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1138.5291 0.9 24120 19073 2 1138.531504 570.2718 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3642.6 - 7.60E+06 - - - 2.0887 - 1.852 0.367 - 494.3 1 2 0 0.0024 9 0 0 0 8.14E+07 9.09E+07 - - - 3.5338 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19075.19075.2 1.52 16-Sep R.LQLPVWEYK[136.11].D sp|O43143|DHX15_HUMAN 1 1182.6528 2.39 24121 19075 2 1182.654722 592.3337 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 3642.8 - 2.06E+06 - - - 1.5863 - 1.718 0.331 - 321.5 1 2 0 0.0019 9 0 0 0 8.71E+07 3.64E+07 - - - 3.0508 0.9965 230117_WJC_METTL3_WT_vs_EV_F03.19076.19076.2 0.122 16-Sep K.SGILPILVK.C sp|O00505|IMA4_HUMAN 1 938.6165 1.35 24122 19076 2 938.621275 470.3155 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3642.9 - 2.21E+06 - - - 5.1363 - 1.576 0.405 - 195.6 1 2 0 0.0048 9 0 0 0 3.35E+07 2.48E+07 - - - 3.3468 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19077.19077.2 0.00384 16-Nov K.SGILPILVK[136.11].C sp|O00505|IMA4_HUMAN 1 946.6307 1.35 24123 19077 2 946.633166 474.3226 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3643 - 1.80E+06 - - - 2.6536 - 1.513 0.409 - 254.2 1 2 0 0.0025 9 0 0 0 3.35E+07 2.48E+07 - - - 3.2591 0.9336 230117_WJC_METTL3_WT_vs_EV_F03.19078.19078.2 0.014 16-Nov S.GDLLSEVER.N "sp|O14513|NCKP5_HUMAN,tr|A0A0A0MSE4|A0A0A0MSE4_HUMAN,tr|A0A0A0MS79|A0A0A0MS79_HUMAN" 3 1016.5138 10.18 24124 19078 2 1016.51782 509.2642 Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=2 4.14 3643.1 - 1.22E+06 - - - 3.9163 - 2.29 0.4 - 536.4 1 1 0 0.004 9 0 0 0 7.62E+07 7.48E+06 - - - 4.3912 0.9808 230117_WJC_METTL3_WT_vs_EV_F03.19079.19079.2 1.17 14-Jul R.VLLLPLER.D sp|O95071|UBR5_HUMAN 1 951.6117 1.62 24125 19079 2 951.614628 476.8131 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3643.2 - 922606 - - - 3.0737 - 1.355 0.069 - 143.9 1 2 0 0.0029 8 0 0 0 1.96E+07 1.21E+07 - - - 0.466 1 230117_WJC_METTL3_WT_vs_EV_F03.19087.19087.2 0.00097 20-Nov K.MALDIEIATYR.K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1294.6591 1.39 24132 19087 2 1294.6627 648.3368 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3644.2 - 447345 - - - 2.7629 - 2.319 0.451 - 512.4 1 2 0 0.0036 11 0 0 0 8.85E+07 6.36E+07 - - - 4.6464 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19089.19089.2 0.0366 16-Jul K.IIDGLLVMR.K "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1028.6052 3.32 24133 19089 2 1028.607848 515.3099 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.84 3644.4 - 4.92E+06 - - - 2.5384 - 1.571 0.354 - 103 1 2 0 0.0026 9 0 0 0 8.78E+07 2.64E+07 - - - 2.9617 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19090.19090.2 3.91E-05 18-Oct K.SVPDEIILLR.S sp|Q9H9A6|LRC40_HUMAN 1 1153.6707 2.2 24134 19090 2 1153.674042 577.8426 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.37 3644.5 - 1.41E+06 - - - 2.9194 - 1.85 0.491 - 466.2 1 2 0 0.0034 10 0 0 0 2.31E+07 1.05E+07 - - - 4.3836 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.19091.19091.2 0.00681 14-Jun R.IPLNDLFR[166.11].C sp|P13473|LAMP2_HUMAN 1 996.5632 7.74 24135 19091 2 996.565185 499.2889 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3644.5 - 1.41E+06 - - - 2.0059 - 1.387 0.361 - 104.4 1 2 0 0.002 8 0 0 0 9.67E+07 1.25E+07 - - - 2.6934 0.9906 230117_WJC_METTL3_WT_vs_EV_F03.19093.19093.2 0.954 14-May R.VLLLPLER[166.11].D sp|O95071|UBR5_HUMAN 1 961.62 1.5 24137 19093 2 961.621679 481.8173 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3644.6 - 1.07E+06 - - - 1.7741 - 1.24 0.116 - 82.9 1 2 0 0.0017 8 0 0 0 1.96E+07 1.31E+07 - - - 0.546 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19095.19095.2 0.000448 22-Aug K.GALPLDTVTFYK.V sp|P30040|ERP29_HUMAN 1 1323.7075 1.44 24139 19095 2 1323.710025 662.861 Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4 5.83 3644.8 - 612184 - - - 1.9423 - 1.745 0.419 - 206.6 1 2 0 0.0026 12 0 0 0 5.78E+06 4.00E+06 - - - 3.5998 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19096.19096.2 0.00138 24-Nov R.ALGLGLVSPAQLR.V "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|A8MRA7|A8MRA7_HUMAN" 3 1293.7769 3.65 24140 19096 2 1293.779906 647.8957 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 9.79 3644.9 - 511362 - - - 2.3458 - 2.637 0.249 - 475.9 1 2 0 0.003 13 0 0 0 5.49E+06 1.50E+06 - - - 3.3678 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19097.19097.2 0.0201 16-Aug R.LTAILLQIK.C "sp|Q5TKA1|LIN9_HUMAN,tr|C9J5J4|C9J5J4_HUMAN,tr|H0Y322|H0Y322_HUMAN,tr|H7C4T7|H7C4T7_HUMAN" 4 1011.6692 1.81 24141 19097 2 1011.670864 506.8419 Protein lin-9 homolog OS=Homo sapiens OX=9606 GN=LIN9 PE=1 SV=1 8.75 3645 - 285617 - - - 1.627 - 1.463 0.385 - 121.3 1 2 0 0.0016 9 0 0 0 1.94E+06 1.07E+06 - - - 2.9849 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.19098.19098.2 2.91 14-Jun K.MIDLIIPR[166.11].G sp|P54886|P5CS_HUMAN 1 979.5764 1.56 24142 19098 2 979.579029 490.7955 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 5.59 3645.1 - 216341 - - - 2.691 - 1.457 0.214 - 103.6 2 2 0 0.0026 8 0 0 0 7.49E+06 4.79E+06 - - - 1.6214 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.19099.19099.2 5.22E-07 Dec-32 R.AAVEEGIVLGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1683.8978 2.29 24143 19099 2 1683.907099 842.9562 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3645.2 - 164831 - - - 5.5277 - 2.709 0.406 - 314.8 1 2 0 0.0093 17 0 0 0 9.83E+05 4.29E+05 - - - 4.4869 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19101.19101.2 0.00724 18-Sep R.LEPVIMELER[166.11].Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1237.6616 0.59 24144 19101 2 1237.664054 619.8381 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3645.5 - 4.80E+06 - - - 1.9989 - 1.748 0.38 - 351.6 1 2 0 0.0025 10 0 0 0 4.31E+07 7.28E+07 - - - 3.4058 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.19104.19104.2 0.0118 14-Sep K.MIDLIIPR.G sp|P54886|P5CS_HUMAN 1 969.5681 1.53 24146 19104 2 969.572385 485.7913 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 5.59 3645.8 - 669366 - - - 4.3958 - 1.795 0.328 - 313.7 1 2 0 0.0043 8 0 0 0 7.49E+06 4.90E+06 - - - 3.2266 1 230117_WJC_METTL3_WT_vs_EV_F03.19106.19106.2 2.42E-08 20-Dec R.FSTIEEFSYIR.R "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1390.6769 1.23 24148 19106 2 1390.6826 696.3457 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 4.53 3646 - 541522 - - - 4.1117 - 2.572 0.603 - 631.5 1 2 0 0.0057 11 0 0 0 4.27E+06 3.47E+06 - - - 6.0486 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.19108.19108.2 0.0338 12-Aug R.IQLLVFK[136.11].H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 867.5673 0.71 24150 19108 2 867.569069 434.7909 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3646.3 - 392032 - - - 2.0102 - 1.907 0.074 - 193.8 1 2 0 0.0017 7 0 0 0 1.74E+07 2.44E+07 - - - 1.6324 1 230117_WJC_METTL3_WT_vs_EV_F03.19109.19109.2 1.34E-06 20-Nov R.FSTIEEFSYIR[166.11].R "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1400.6852 1.23 24151 19109 2 1400.694362 701.3499 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 4.53 3646.4 - 346342 - - - 6.5754 - 2.095 0.509 - 374.3 1 2 0 0.0092 11 0 0 0 4.27E+06 3.47E+06 - - - 4.7982 1 230117_WJC_METTL3_WT_vs_EV_F03.19113.19113.2 0.000172 14/20 K.LLEVQILEVQR.A "sp|Q8IWJ2|GCC2_HUMAN,tr|H7BYJ9|H7BYJ9_HUMAN" 2 1338.7871 1.66 24155 19113 2 1338.791437 670.4008 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.53 3646.9 - 178139 - - - 3.2388 - 2.765 0.435 - 975.3 1 2 0 0.0043 11 0 0 0 2.71E+06 1.63E+06 - - - 5.0039 0.9931 230117_WJC_METTL3_WT_vs_EV_F03.19114.19114.2 0.443 20-Jul K.LFGALTPLEPR[166.11].L "sp|O14617|AP3D1_HUMAN,tr|A0A087WYN6|A0A087WYN6_HUMAN,tr|A0A2R8Y4J3|A0A2R8Y4J3_HUMAN" 3 1222.6949 2.21 24156 19114 2 1222.700782 612.3547 AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1 6 3647.1 - 149758 - - - 4.787 - 1.519 0.28 - 100.5 1 2 0 0.0059 11 0 0 0 2.71E+06 1.23E+06 - - - 2.2382 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.19119.19119.2 1.07 16-Aug R.LQLPVWEYK.D sp|O43143|DHX15_HUMAN 1 1174.6386 2.45 24159 19119 2 1174.641332 588.3266 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 3647.7 - 2.33E+06 - - - 2.2867 - 1.679 0.179 - 174.2 1 2 0 0.0027 9 0 0 0 8.81E+07 3.60E+07 - - - 1.8614 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.19123.19123.2 0.671 18-Sep R.AVLDALLEGK[136.11].A "sp|P46821|MAP1B_HUMAN,sp|P78559|MAP1A_HUMAN,tr|E9PGC8|E9PGC8_HUMAN" 3 1035.6056 1.84 24163 19123 2 1035.607136 518.8101 Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2 4.37 3648.2 - 965232 - - - 1.5208 - 1.483 0.145 - 186.6 1 2 0 0.0016 10 0 0 0 4.99E+07 2.72E+07 - - - 1.2114 0.984 230117_WJC_METTL3_WT_vs_EV_F03.19124.19124.2 0.117 14-Sep K.GLLQLQWK[136.11].Q sp|O94826|TOM70_HUMAN 1 992.5899 1.37 24164 19124 2 992.59631 497.3022 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.75 3648.4 - 853448 - - - 6.5062 - 1.725 0.256 - 237.2 1 2 0 0.0065 8 0 0 0 8.20E+06 5.98E+06 - - - 2.5742 0.9634 230117_WJC_METTL3_WT_vs_EV_F03.19125.19125.2 1.02 12-Aug R.IQLLVFK.H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 859.5531 0.71 24165 19125 2 859.558456 430.7838 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3648.5 - 846436 - - - 6.2021 - 1.693 0.116 - 209 1 2 0 0.0053 7 0 0 0 1.74E+07 2.44E+07 - - - 1.5644 0.9961 230117_WJC_METTL3_WT_vs_EV_F03.19127.19127.2 6.63E-05 18-Dec K.SVVTSIFGVK[136.11].N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1043.6106 1.64 24167 19127 2 1043.617043 522.8126 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3648.8 - 571723 - - - 6.1287 - 2.272 0.431 - 371.4 1 2 0 0.0064 10 0 0 0 2.83E+07 1.73E+07 - - - 4.5131 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.19129.19129.2 0.00907 16-Oct K.LLIYWASTR.E sp|P06312|KV401_HUMAN 1 1121.6233 281.95 24169 19129 2 1121.627601 561.8189 Immunoglobulin kappa variable 4-1 OS=Homo sapiens OX=9606 GN=IGKV4-1 PE=1 SV=1 8.75 3649 - 540508 - - - 3.8079 - 2.086 0.328 - 359.4 1 2 0 0.0043 9 0 0 0 3.72E+07 1.32E+05 - - - 3.5894 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.19132.19132.2 0.00166 15/22 K.LSTIALALGVER[166.11].T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1251.7426 2.14 24172 19132 2 1251.750199 626.8786 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3649.4 - 303332 - - - 6.0651 - 2.627 0.405 - 828.7 1 2 0 0.0076 12 0 0 0 3.26E+07 1.52E+07 - - - 4.5712 0.924 230117_WJC_METTL3_WT_vs_EV_F03.19135.19135.2 0.00135 24-Sep R.SYEAVAAAAASVY.N sp|Q9BWF3|RBM4_HUMAN 1 1271.6034 - 24175 19135 2 1271.607886 636.809 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4 3649.8 - 245231 - - - 3.5412 - 1.662 0.436 - 214 1 1 0 0.0045 13 0 0 0 - - - - - 3.5637 0.9852 230117_WJC_METTL3_WT_vs_EV_F03.19141.19141.2 0.00813 18-Aug R.LEPVIMELER.Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1227.6533 0.55 24180 19141 2 1227.658943 614.8339 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3650.6 - 608388 - - - 4.5884 - 1.769 0.107 - 169 1 2 0 0.0056 10 0 0 0 3.94E+07 7.14E+07 - - - 1.4217 1 230117_WJC_METTL3_WT_vs_EV_F03.19142.19142.2 0.00137 14/22 K.LSTIALALGVER.T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1241.7343 2.14 24181 19142 2 1241.740649 621.8744 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3650.6 - 5.36E+06 - - - 5.0832 - 2.593 0.422 - 728.1 1 2 0 0.0063 12 0 0 0 3.26E+07 1.52E+07 - - - 4.6629 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19143.19143.2 0.0315 16-Oct K.EAEILEVLR[166.11].H sp|P36551|HEM6_HUMAN 1 1080.6054 0.84 24182 19143 2 1080.606631 541.31 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.25 3650.7 - 2.26E+06 - - - 1.0975 - 2.237 0.273 - 292.2 1 2 0 0.0012 9 0 0 0 9.25E+06 1.10E+07 - - - 3.3863 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.19144.19144.2 0.0382 14-Sep K.ILTPIIFK.E "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5L9|H7C5L9_HUMAN" 4 943.6106 0.64 24183 19144 2 943.616258 472.8126 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 8.75 3650.9 - 2.15E+06 - - - 5.9537 - 1.903 0.454 - 222 1 2 0 0.0056 8 0 0 0 1.16E+07 1.82E+07 - - - 4.333 0.9772 230117_WJC_METTL3_WT_vs_EV_F03.19146.19146.2 0.0157 12-Jul R.DYLQLLR.K sp|L0R6Q1|S35U4_HUMAN 1 919.5127 1.82 24185 19146 2 919.517768 460.7636 SLC35A4 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=SLC35A4 PE=3 SV=1 5.84 3651.1 - 1.73E+06 - - - 5.4931 - 1.256 0.245 - 253.5 1 2 0 0.0051 7 0 0 0 6.38E+06 3.50E+06 - - - 1.5712 1 230117_WJC_METTL3_WT_vs_EV_F03.19147.19147.2 0.000164 16-Nov R.QINWTVLYR.R "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1191.64 1 24186 19147 2 1191.646651 596.8273 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 8.75 3651.2 - 1.11E+06 - - - 5.5453 - 2.436 0.421 - 720.7 1 2 0 0.0066 9 0 0 0 3.73E+07 3.74E+07 - - - 4.7243 1 230117_WJC_METTL3_WT_vs_EV_F03.19149.19149.2 8.95E-06 18-Oct R.LWIANYSLPR.A sp|O43172|PRP4_HUMAN 1 1231.6713 3.27 24188 19149 2 1231.677283 616.8429 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3651.5 - 863220 - - - 4.8227 - 2.072 0.518 - 519.1 1 2 0 0.0059 10 0 0 0 1.06E+08 3.25E+07 - - - 4.8986 0.9921 230117_WJC_METTL3_WT_vs_EV_F03.19150.19150.2 7.01E-05 20-Oct K.ELFPIQMEGVK.L "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 1289.669 1.16 24189 19150 2 1289.678096 645.8418 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.53 3651.6 - 731472 - - - 7.084 - 1.874 0.466 - 311.5 1 2 0 0.0091 11 0 0 0 2.87E+06 2.48E+06 - - - 4.1791 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.19154.19154.3 0.0432 Dec-44 K.LSTIALALGVER.T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1241.7343 1.82 24193 19154 3 1241.740878 414.9187 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3652.1 - 326347 - - - 5.2676 - 2.119 0.313 - 119 1 2 0 0.0065 12 0 0 0 1.40E+06 7.70E+05 - - - 4.1093 0.9425 230117_WJC_METTL3_WT_vs_EV_F03.19155.19155.2 2.36E-05 18-Nov R.PILYSNWLSK.D "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 24 1219.6601 0.02 24194 19155 2 1219.660564 610.8373 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.01 3652.3 - 298515 - - - 0.3722 - 2.008 0.263 - 334.4 1 1 0 0.0005 10 0 0 0 6.20E+06 4.10E+08 - - - 2.9293 0.9642 230117_WJC_METTL3_WT_vs_EV_F03.19156.19156.2 0.181 14-Aug K.LAIVLFTK[136.11].E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 911.5935 1.85 24195 19156 2 911.598565 456.804 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3652.4 - 247822 - - - 5.5123 - 1.709 0.074 - 145.3 1 2 0 0.005 8 0 0 0 3.59E+06 1.95E+06 - - - 1.2023 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19162.19162.2 0.0031 20-Aug K.LFGALTPLEPR.L "sp|O14617|AP3D1_HUMAN,tr|A0A087WYN6|A0A087WYN6_HUMAN,tr|A0A2R8Y4J3|A0A2R8Y4J3_HUMAN" 3 1212.6867 2.35 24200 19162 2 1212.686642 607.3506 AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1 6 3653.1 - 413089 - - - -0.014 - 1.568 0.414 - 128.2 1 2 0 0 11 0 0 0 4.14E+06 1.76E+06 - - - 3.3156 0.998 230117_WJC_METTL3_WT_vs_EV_F03.19163.19163.2 0.0227 18-Nov R.IIVAIDGWPR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1138.6499 2.33 24201 19163 2 1138.653249 570.3322 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3653.2 - 6.87E+06 - - - 2.9596 - 2.304 0.124 - 428.8 1 2 0 0.0034 10 0 0 0 6.50E+07 2.79E+07 - - - 2.2856 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19164.19164.2 0.0117 16-Sep K.VFSIGPVFR[166.11].A sp|P14868|SYDC_HUMAN 1 1030.5839 1.12 24202 19164 2 1030.586216 516.2992 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3653.2 - 3.11E+06 - - - 2.2259 - 1.806 0.391 - 318 1 2 0 0.0023 9 0 0 0 4.25E+07 3.78E+07 - - - 3.6383 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.19165.19165.2 0.00149 16-Sep K.VFSIGPVFR.A sp|P14868|SYDC_HUMAN 1 1020.5757 1.12 24203 19165 2 1020.57882 511.2951 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3653.3 - 2.97E+06 - - - 3.1041 - 1.659 0.349 - 308.8 1 2 0 0.0032 9 0 0 0 4.25E+07 3.78E+07 - - - 3.0822 0.9738 230117_WJC_METTL3_WT_vs_EV_F03.19168.19168.2 4.88E-06 16-Oct K.MDLVTYFGK.R sp|P09543|CN37_HUMAN 1 1072.5263 4.2 24206 19168 2 1073.531963 537.2704 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 5.59 3653.6 - 531325 - - - 937.6413 - 2.183 0.484 - 331.1 1 2 0 1.0056 9 0 0 0 1.35E+07 3.22E+06 - - - 4.5587 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19169.19169.2 0.258 14-Oct K.LAIVLFTK.E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 903.5793 1.85 24207 19169 2 903.581321 452.7969 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3653.7 - 494242 - - - 2.1924 - 2.012 0.201 - 273.4 1 2 0 0.002 8 0 0 0 3.59E+06 1.95E+06 - - - 2.6335 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19170.19170.2 0.025 18-Aug K.LLVLSALAEK.L sp|Q13395|TARB1_HUMAN 1 1055.659 1.81 24208 19170 2 1055.661632 528.8368 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6 3653.7 - 480907 - - - 2.4487 - 1.647 0.383 - 137.7 1 2 0 0.0026 10 0 0 0 4.31E+06 2.38E+06 - - - 3.2618 0.866 230117_WJC_METTL3_WT_vs_EV_F03.19172.19172.2 0.116 14-Jun R.SIFDYALR[166.11].S "sp|Q99570|PI3R4_HUMAN,tr|D6RBB7|D6RBB7_HUMAN,tr|D6RJ98|D6RJ98_HUMAN,tr|D6RAC3|D6RAC3_HUMAN" 4 993.5159 2.66 24210 19172 2 993.522955 497.7652 Phosphoinositide 3-kinase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PIK3R4 PE=1 SV=3 5.55 3654 - 219057 - - - 7.099 - 1.114 0.207 - 88.7 1 2 0 0.0071 8 0 0 0 2.83E+06 1.06E+06 - - - 0.8933 0.8883 230117_WJC_METTL3_WT_vs_EV_F03.19179.19179.2 2.26 12-Jun K.QFLDYFK.T "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 959.4753 1.63 24215 19179 2 959.479131 480.7449 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.83 3654.9 - 958860 - - - 4.0251 - 1.151 0.023 - 135.7 1 2 0 0.0039 7 0 0 0 9.65E+06 5.91E+06 - - - -0.3447 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.19180.19180.2 6.24E-05 18-Aug K.ELPEYYELIR.K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1323.6711 1.62 24216 19180 2 1323.676833 662.8428 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3655.1 - 857087 - - - 4.3553 - 1.975 0.394 - 287.4 1 2 0 0.0058 10 0 0 0 1.58E+07 9.74E+06 - - - 3.8489 0.999 230117_WJC_METTL3_WT_vs_EV_F03.19181.19181.2 0.00251 18-Sep K.ELPEYYELIR[166.11].K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1333.6793 1.62 24217 19181 2 1333.68313 667.8469 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3655.2 - 626789 - - - 2.8433 - 1.606 0.357 - 345 1 2 0 0.0038 10 0 0 0 1.58E+07 9.74E+06 - - - 2.999 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.19183.19183.2 0.018 20-Dec R.GVIFTEAFVAR.H sp|O94874|UFL1_HUMAN 1 1208.6554 2.63 24219 19183 2 1208.661006 605.335 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 6 3655.5 - 503428 - - - 4.6721 - 2.474 0.395 - 373.3 1 2 0 0.0056 11 0 0 0 9.34E+06 3.56E+06 - - - 4.4072 0.9911 230117_WJC_METTL3_WT_vs_EV_F03.19185.19185.2 0.072 12-Aug R.LDFLPLK.C "sp|Q8WV99|ZFN2B_HUMAN,tr|F8WEE4|F8WEE4_HUMAN,tr|E9PFU9|E9PFU9_HUMAN,tr|C9J1R6|C9J1R6_HUMAN,tr|B4DEN4|B4DEN4_HUMAN,tr|A0A087X0D9|A0A087X0D9_HUMAN,tr|B8ZZ56|B8ZZ56_HUMAN,tr|E7EV05|E7EV05_HUMAN" 8 844.5058 1 24221 19185 2 844.510981 423.2602 AN1-type zinc finger protein 2B OS=Homo sapiens OX=9606 GN=ZFAND2B PE=1 SV=1 5.84 3655.7 - 445229 - - - 6.0864 - 1.823 0.272 - 190.7 1 2 0 0.0051 7 0 0 0 5.91E+06 5.90E+06 - - - 2.951 1 230117_WJC_METTL3_WT_vs_EV_F03.19186.19186.2 9.86E-06 22-Nov R.LC[160.03]LTDEEVVFVR.L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1478.7439 7.59 24222 19186 2 1478.748747 740.3792 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3655.8 - 386846 - - - 3.267 - 2.502 0.559 - 475.9 1 2 0 0.0048 12 0 0 0 6.44E+06 8.48E+05 - - - 5.5813 0.997 230117_WJC_METTL3_WT_vs_EV_F03.19191.19191.2 0.00102 18-Sep R.IIVAIDGWPR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1148.6581 3.26 24226 19191 2 1148.664653 575.3364 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3656.5 - 3.07E+06 - - - 5.6623 - 2.017 0.448 - 261.9 1 2 0 0.0065 10 0 0 0 9.27E+07 2.84E+07 - - - 4.3063 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.19193.19193.2 0.143 18-Jun R.LWIANYSLPR[166.11].A sp|O43172|PRP4_HUMAN 1 1241.6796 3.32 24228 19193 2 1241.682046 621.8471 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3656.6 - 4.94E+06 - - - 1.9594 - 1.315 0.201 - 127.6 1 2 0 0.0024 10 0 0 0 1.06E+08 3.20E+07 - - - 1.2892 0.999 230117_WJC_METTL3_WT_vs_EV_F03.19195.19195.2 0.00223 16-Sep K.ISVNDFIIK[136.11].A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1055.6106 0.8 24230 19195 2 1055.612676 528.8126 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 3656.7 - 997420 - - - 1.9221 - 1.602 0.285 - 143.1 1 2 0 0.002 9 0 0 0 9.70E+06 1.21E+07 - - - 2.5087 1 230117_WJC_METTL3_WT_vs_EV_F03.19196.19196.2 1.01E-06 22-Nov R.VVYSAFLMATPR.L sp|Q15029|U5S1_HUMAN 1 1353.7115 1.38 24231 19196 2 1353.714951 677.863 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.72 3656.9 - 938925 - - - 2.5545 - 2.473 0.473 - 429 1 2 0 0.0035 12 0 0 0 1.01E+07 7.31E+06 - - - 4.9158 0.999 230117_WJC_METTL3_WT_vs_EV_F03.19197.19197.2 0.0171 16-Aug K.ISVNDFIIK.A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1047.5964 0.82 24232 19197 2 1047.599013 524.8055 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 3656.9 - 833895 - - - 2.4494 - 1.7 0.29 - 105.4 1 2 0 0.0026 9 0 0 0 9.70E+06 1.19E+07 - - - 2.7173 1 230117_WJC_METTL3_WT_vs_EV_F03.19198.19198.2 3.06E-08 22-Dec R.VVYSAFLMATPR[166.11].L sp|Q15029|U5S1_HUMAN 1 1363.7198 1.39 24233 19198 2 1363.722188 682.8672 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.72 3657.1 - 647298 - - - 1.7782 - 2.406 0.54 - 538.5 1 2 0 0.0024 12 0 0 0 1.02E+07 7.31E+06 - - - 5.3388 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19199.19199.2 0.000599 22-Dec K.VLGTEELYGYLK[136.11].K "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1391.7428 1.01 24234 19199 2 1391.746843 696.8787 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.53 3657.2 - 613641 - - - 2.9172 - 2.26 0.454 - 350.3 1 2 0 0.0041 12 0 0 0 1.14E+07 1.13E+07 - - - 4.5383 1 230117_WJC_METTL3_WT_vs_EV_F03.19200.19200.2 2.50E-05 22-Nov R.LC[160.03]LTDEEVVFVR[166.11].L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1488.7522 7.59 24235 19200 2 1488.754315 745.3834 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3657.3 - 264343 - - - 1.4301 - 2.354 0.476 - 427.2 1 2 0 0.0021 12 0 0 0 6.44E+06 8.48E+05 - - - 4.8087 0.971 230117_WJC_METTL3_WT_vs_EV_F03.19201.19201.2 5.93E-06 13/24 V.ALVMLQEDELLSK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1495.8047 1.47 24236 19201 2 1495.808537 748.9096 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3657.5 - 229315 - - - 2.5438 - 2.642 0.391 - 545.2 1 1 0 0.0038 13 0 0 0 2.88E+07 1.96E+07 - - - 4.4212 1 230117_WJC_METTL3_WT_vs_EV_F03.19203.19203.2 0.000146 13/22 K.VLGTEELYGYLK.K "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1383.7286 1.01 24237 19203 2 1383.733306 692.8716 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.53 3657.7 - 723663 - - - 3.4132 - 2.58 0.488 - 464.6 1 2 0 0.0047 12 0 0 0 1.14E+07 1.13E+07 - - - 5.1377 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19206.19206.2 0.000365 18-Aug R.FFLSSGLIDK[136.11].V sp|Q9BTV4|TMM43_HUMAN 1 1133.6212 0.89 24239 19206 2 1133.622095 567.8179 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 5.84 3657.9 - 1.25E+06 - - - 0.7798 - 1.519 0.4 - 139.9 1 2 0 0.0009 10 0 0 0 1.05E+07 1.17E+07 - - - 3.162 1 230117_WJC_METTL3_WT_vs_EV_F03.19207.19207.2 3.40E-07 15/24 V.ALVMLQEDELLSK.M sp|Q96A49|SYAP1_HUMAN 1 1487.7905 1.47 24240 19207 2 1487.794689 744.9025 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3658 - 1.27E+06 - - - 2.7941 - 3.037 0.548 - 818.8 1 1 0 0.0042 13 0 0 0 2.88E+07 1.96E+07 - - - 5.9383 0.9596 230117_WJC_METTL3_WT_vs_EV_F03.19211.19211.2 1.6 14-May K.GLLDVLPK[136.11].N "sp|O95071|UBR5_HUMAN,tr|E7ET84|E7ET84_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 861.5415 2.63 24244 19211 2 861.542754 431.778 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.84 3658.3 - 386628 - - - 1.4509 - 0.995 0.133 - 42 11 2 0 0.0013 8 0 0 0 1.14E+07 4.32E+06 - - - -0.4574 1 230117_WJC_METTL3_WT_vs_EV_F03.19221.19221.2 5.45E-06 13/20 K.MALDIEIAAYR.K "sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,sp|P12036|NFH_HUMAN,sp|P07196|NFL_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 6 1264.6486 1.24 24252 19221 2 1264.650761 633.3316 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.37 3659.4 - 962138 - - - 1.7412 - 2.719 0.527 - 866.3 1 2 0 0.0022 11 0 0 0 8.67E+06 7.01E+06 - - - 5.6387 1 230117_WJC_METTL3_WT_vs_EV_F03.19222.19222.2 1.77E-05 16/24 R.IPSPLGYAAIPIK[136.11].F sp|Q9Y3A4|RRP7A_HUMAN 1 1346.8053 1.34 24253 19222 2 1346.808011 674.4099 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 8.59 3659.6 - 755756 - - - 1.9951 - 2.437 0.57 - 514.2 1 2 0 0.0027 13 0 0 0 2.22E+07 1.65E+07 - - - 5.5364 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.19223.19223.2 0.0014 18-Nov R.VTIMGIYSIK[136.11].K "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 3 1131.6453 1.67 24254 19223 2 1131.649798 566.8299 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 8.56 3659.6 - 1.21E+06 - - - 3.9588 - 1.956 0.355 - 333.7 1 2 0 0.0045 10 0 0 0 1.84E+07 1.10E+07 - - - 3.5343 1 230117_WJC_METTL3_WT_vs_EV_F03.19224.19224.3 2.46E-06 18/56 K.LLQVASPFLEPHLVR.M "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1717.9879 2.83 24255 19224 3 1717.992252 573.6699 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 6.75 3659.8 - 829981 - - - 2.5181 - 3.367 0.497 - 412.8 1 2 0 0.0043 15 0 0 0 7.18E+06 2.54E+06 - - - 7.2477 1 230117_WJC_METTL3_WT_vs_EV_F03.19225.19225.2 1.66E-08 14/22 R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.22 24256 19225 2 1315.789561 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3659.9 - 823464 - - - 2.4229 - 2.537 0.592 - 571.7 1 2 0 0.0032 12 0 0 0 7.38E+08 6.06E+08 - - - 5.8621 1 230117_WJC_METTL3_WT_vs_EV_F03.19226.19226.2 1.71E-05 16-Oct K.IFAFDLDAK.R sp|Q96P11|NSUN5_HUMAN 1 1038.5386 0.75 24257 19226 2 1038.540089 520.2766 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 4.21 3660 - 741310 - - - 1.4366 - 2.025 0.505 - 280.9 1 2 0 0.0015 9 0 0 0 7.92E+06 1.06E+07 - - - 4.8117 1 230117_WJC_METTL3_WT_vs_EV_F03.19227.19227.2 0.000174 13/26 K.VLELDPALAPVVSR.E "sp|O00170|AIP_HUMAN,tr|A0A804HKK3|A0A804HKK3_HUMAN,tr|A0A804HKL7|A0A804HKL7_HUMAN,tr|A0A804HJ46|A0A804HJ46_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN" 6 1477.8504 4.79 24258 19227 2 1477.853951 739.9325 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 4.37 3660.1 - 664077 - - - 2.3825 - 2.494 0.523 - 363.7 1 2 0 0.0035 14 0 0 0 1.16E+07 2.43E+06 - - - 5.1961 0.9967 230117_WJC_METTL3_WT_vs_EV_F03.19228.19228.2 0.305 16-Oct K.GVILLIVDK.A "sp|P78344|IF4G2_HUMAN,tr|H0YE44|H0YE44_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 8 968.627 1.84 24259 19228 2 968.629659 485.3208 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.84 3660.3 - 625602 - - - 2.7265 - 1.881 0.108 - 272.1 1 2 0 0.0026 9 0 0 0 9.22E+06 5.01E+06 - - - 1.6657 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19230.19230.2 0.000157 18-Aug R.FMEPYIFGSR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 1255.5935 1.07 24261 19230 2 1255.59393 628.804 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 6 3660.5 - 282259 - - - 0.3425 - 1.776 0.411 - 241.9 1 2 0 0.0004 10 0 0 0 4.68E+06 4.36E+06 - - - 3.6797 0.9875 230117_WJC_METTL3_WT_vs_EV_F03.19231.19231.2 0.897 12-Jun R.LWAELLR[166.11].T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN" 3 909.5312 1.55 24262 19231 2 909.5331 455.7729 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 6 3660.7 - 245380 - - - 2.1352 - 1.349 0.077 - 111.6 2 2 0 0.0019 7 0 0 0 4.04E+06 2.60E+06 - - - 0.4232 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.19232.19232.2 0.0512 20-Aug R.GVIFTEAFVAR[166.11].H sp|O94874|UFL1_HUMAN 1 1218.6636 2.53 24263 19232 2 1218.667311 610.3391 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 6 3660.8 - 229772 - - - 3.0213 - 1.693 0.336 - 107.2 1 2 0 0.0037 11 0 0 0 9.34E+06 3.69E+06 - - - 2.9459 1 230117_WJC_METTL3_WT_vs_EV_F03.19234.19234.2 2.25E-06 14/26 R.WSSLAC[160.03]NIALDAVK.M "sp|P49368|TCPG_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1546.7814 -1 24265 19234 2 1546.791026 774.398 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.83 3661.1 - 173434 - - - 6.2465 - 2.452 0.585 - 547.3 1 2 0 0.0097 14 0 0 0 0.00E+00 0.00E+00 - - - 5.6095 1 230117_WJC_METTL3_WT_vs_EV_F03.19237.19237.2 0.000557 13/22 R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.22 24266 19237 2 1323.804304 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3661.4 - 2.80E+07 - - - 2.8184 - 2.287 0.486 - 423 1 2 0 0.0037 12 0 0 0 7.38E+08 6.06E+08 - - - 4.806 1 230117_WJC_METTL3_WT_vs_EV_F03.19239.19239.2 3.33E-08 24-Dec R.IITLTGPTNAIFK.A sp|Q15365|PCBP1_HUMAN 1 1387.8075 3.44 24268 19239 2 1387.81028 694.911 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3661.5 - 3.13E+06 - - - 2.0017 - 2.358 0.572 - 416.9 1 2 0 0.0028 13 0 0 0 7.79E+07 2.26E+07 - - - 5.4665 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.19240.19240.2 0.00128 22-Dec K.ATGILLYGLASR.L "sp|P47897|SYQ_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|F2Z2V6|F2Z2V6_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 9 1233.7081 1.57 24269 19240 2 1233.713572 617.8613 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 8.79 3661.6 - 2.93E+06 - - - 4.4176 - 2.358 0.388 - 544.1 1 2 0 0.0054 12 0 0 0 1.40E+07 8.94E+06 - - - 4.1621 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.19241.19241.2 2.29 14-Jun R.QWELLLEK.M "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SFF6|A0A0D9SFF6_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN,tr|A0A5F9ZHC3|A0A5F9ZHC3_HUMAN" 5 1057.5808 0.79 24270 19241 2 1057.582209 529.7977 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 3661.7 - 1.94E+06 - - - 1.3351 - 1.334 0.151 - 142.2 1 2 0 0.0014 8 0 0 0 7.91E+06 1.01E+07 - - - 1.025 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19242.19242.2 0.000469 16-Aug K.IFAFDLDAK[136.11].R sp|Q96P11|NSUN5_HUMAN 1 1046.5528 0.75 24271 19242 2 1046.555433 524.2837 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 4.21 3661.7 - 1.68E+06 - - - 2.5187 - 1.677 0.475 - 141.5 1 2 0 0.0026 9 0 0 0 7.92E+06 1.06E+07 - - - 4.0442 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.19243.19243.2 0.0212 14-Jul K.GLLDVLPK.N "sp|O95071|UBR5_HUMAN,tr|E7ET84|E7ET84_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 853.5273 2.49 24272 19243 2 853.528416 427.7709 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.84 3661.8 - 1.35E+06 - - - 1.3028 - 1.386 0.28 - 151.8 1 2 0 0.0011 8 0 0 0 1.19E+07 4.78E+06 - - - 2.0932 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19244.19244.2 0.00147 16-Jul K.GVILLIVDK[136.11].A "sp|P78344|IF4G2_HUMAN,tr|H0YE44|H0YE44_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 8 976.6412 1.86 24273 19244 2 976.643366 489.3279 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.84 3661.9 - 1.27E+06 - - - 2.1994 - 1.859 0.453 - 101.3 1 2 0 0.0021 9 0 0 0 9.22E+06 4.95E+06 - - - 4.18 1 230117_WJC_METTL3_WT_vs_EV_F03.19245.19245.2 4.65E-09 20-Dec R.FFDEESYSLLR.K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1404.6561 1.57 24274 19245 2 1404.657852 703.3353 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3662 - 693645 - - - 1.2145 - 2.492 0.583 - 329.7 1 2 0 0.0017 11 0 0 0 3.40E+07 2.16E+07 - - - 5.8166 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.19246.19246.3 2.30E-05 Nov-44 R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 0.34 24275 19246 3 1315.788389 439.6027 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3662.1 - 681123 - - - 1.5322 - 1.993 0.487 - 121.4 1 2 0 0.002 12 0 0 0 1.03E+07 3.05E+07 - - - 5.8806 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.19247.19247.2 1.16 24-Nov K.LGLSLVVPGGGIK.K sp|Q99747|SNAG_HUMAN 1 1208.7493 3.08 24276 19247 2 1208.75256 605.3819 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3662.2 - 632511 - - - 2.7309 - 2.166 0.233 - 225.4 1 2 0 0.0033 13 0 0 0 5.21E+06 1.69E+06 - - - 2.7445 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19249.19249.3 0.0141 Oct-44 R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.09 24278 19249 3 1323.80337 442.2741 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3662.5 - 591069 - - - 2.1129 - 1.855 0.342 - 140.5 1 2 0 0.0028 12 0 0 0 8.99E+06 8.26E+06 - - - 4.0649 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19252.19252.2 4.56E-05 16-Aug R.VLEALLPLK.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 994.6427 1.63 24281 19252 2 994.645208 498.3286 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3662.9 - 461083 - - - 2.5527 - 1.859 0.286 - 203.4 1 2 0 0.0025 9 0 0 0 3.71E+07 2.27E+07 - - - 2.9464 1 230117_WJC_METTL3_WT_vs_EV_F03.19258.19258.2 1.86E-10 13/20 R.FFDEESYSLLR[166.11].K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1414.6644 1.56 24286 19258 2 1414.665759 708.3395 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3663.6 - 2.06E+06 - - - 0.9493 - 2.536 0.513 - 412.1 1 2 0 0.0013 11 0 0 0 3.36E+07 2.16E+07 - - - 5.3471 1 230117_WJC_METTL3_WT_vs_EV_F03.19259.19259.2 5.39E-05 15/24 R.IITLTGPTNAIFK[136.11].A sp|Q15365|PCBP1_HUMAN 1 1395.8217 3.44 24287 19259 2 1395.823091 698.9181 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3663.7 - 2.01E+06 - - - 0.9951 - 2.723 0.491 - 587 1 2 0 0.0014 13 0 0 0 7.79E+07 2.26E+07 - - - 5.2381 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19260.19260.2 0.63 16-Aug R.VLEALLPLK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1002.6569 1.63 24288 19260 2 1002.658869 502.3357 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3663.8 - 1.84E+06 - - - 1.9947 - 1.851 0.28 - 211.3 1 2 0 0.002 9 0 0 0 3.71E+07 2.27E+07 - - - 2.8898 0.998 230117_WJC_METTL3_WT_vs_EV_F03.19261.19261.2 0.176 12-Jul R.LWAELLR.T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN" 3 899.5229 1.55 24289 19261 2 899.52467 450.7687 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 6 3664 - 603229 - - - 1.9811 - 1.497 0.199 - 181.7 1 2 0 0.0018 7 0 0 0 4.04E+06 2.60E+06 - - - 1.7886 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19262.19262.2 0.0491 24-Dec K.LGLSLVVPGGGIK[136.11].K sp|Q99747|SNAG_HUMAN 1 1216.7635 -1 24290 19262 2 1216.767396 609.389 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3664.1 - 565070 - - - 3.2356 - 2.015 0.356 - 284.8 1 2 0 0.0039 13 0 0 0 0.00E+00 0.00E+00 - - - 3.4673 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19263.19263.2 0.00672 18-Sep R.VIEQLLVGLK.D "sp|Q9BTW9|TBCD_HUMAN,tr|A0A804HJ32|A0A804HJ32_HUMAN,tr|A0A804HKT8|A0A804HKT8_HUMAN,tr|A0A804HHW7|A0A804HHW7_HUMAN,tr|A0A804HL21|A0A804HL21_HUMAN,tr|A0A804HKB9|A0A804HKB9_HUMAN,tr|A0A804HJY5|A0A804HJY5_HUMAN,tr|A0A804HI02|A0A804HI02_HUMAN,tr|A0A804HIU1|A0A804HIU1_HUMAN,tr|A0A804HJ57|A0A804HJ57_HUMAN,tr|A0A804HLF8|A0A804HLF8_HUMAN,tr|A0A804HL62|A0A804HL62_HUMAN,tr|A0A804HIC0|A0A804HIC0_HUMAN,tr|J3KR97|J3KR97_HUMAN,tr|A0A804HI57|A0A804HI57_HUMAN,tr|A0A804HIN6|A0A804HIN6_HUMAN,tr|A0A804HLI2|A0A804HLI2_HUMAN" 17 1110.7012 1.32 24291 19263 2 1110.705147 556.3579 Tubulin-specific chaperone D OS=Homo sapiens OX=9606 GN=TBCD PE=1 SV=2 5.97 3664.2 - 458692 - - - 3.5122 - 1.97 0.386 - 159 1 2 0 0.0039 10 0 0 0 1.86E+06 1.41E+06 - - - 3.7834 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19271.19271.2 0.0017 20-Oct K.VAEAVATFLIR.H sp|Q9Y570|PPME1_HUMAN 1 1188.6867 23.99 24299 19271 2 1188.688064 595.3506 Protein phosphatase methylesterase 1 OS=Homo sapiens OX=9606 GN=PPME1 PE=1 SV=3 5.97 3665.3 - 183982 - - - 1.182 - 1.533 0.35 - 187.8 1 2 0 0.0014 11 0 0 0 1.16E+06 4.85E+04 - - - 2.7814 0.9148 230117_WJC_METTL3_WT_vs_EV_F03.19274.19274.2 0.451 28-May R.LLEGGSTALTYALVR.A "tr|A0A087WZT3|A0A087WZT3_HUMAN,tr|A0A0B4J295|A0A0B4J295_HUMAN" 2 1562.8668 -1 24302 19274 2 1562.864318 782.4407 BolA-like protein 2 OS=Homo sapiens OX=9606 GN=BOLA2B PE=1 SV=2 6 3665.6 - 90583.3 - - - -1.5932 - 1.178 0.151 - 28.2 28 2 0 -0.0025 15 0 0 0 0.00E+00 0.00E+00 - - - -0.0882 0.9676 230117_WJC_METTL3_WT_vs_EV_F03.19277.19277.2 1.63 14-Jun R.ILPWSTFR[166.11].L "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1028.5683 0.36 24304 19277 2 1028.570427 515.2914 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3666.1 - 684967 - - - 2.0951 - 1.085 0.066 - 106.3 1 2 0 0.0022 8 0 0 0 6.40E+06 1.77E+07 - - - -0.2262 1 230117_WJC_METTL3_WT_vs_EV_F03.19278.19278.2 8.52E-05 13/18 R.LGLDDFESLK[136.11].V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1143.5903 0.44 24305 19278 2 1143.591015 572.8024 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3666.1 - 5.58E+06 - - - 0.6209 - 2.504 0.554 - 398.5 1 2 0 0.0007 10 0 0 0 1.96E+07 4.48E+07 - - - 5.6947 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19279.19279.2 0.00715 14-Sep R.WALGQVFR[166.11].Q "sp|P26572|MGAT1_HUMAN,tr|D6RF69|D6RF69_HUMAN" 2 985.5373 1.39 24306 19279 2 985.539076 493.7759 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 9.75 3666.2 - 2.12E+06 - - - 1.796 - 1.793 0.349 - 387.7 1 2 0 0.0018 8 0 0 0 6.74E+06 4.84E+06 - - - 3.3791 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19280.19280.2 0.0129 18-Jul R.FLVPIESIER.A sp|Q14249|NUCG_HUMAN 1 1201.6707 4.96 24307 19280 2 1201.671277 601.8426 "Endonuclease G, mitochondrial OS=Homo sapiens OX=9606 GN=ENDOG PE=1 SV=4" 4.53 3666.4 - 1.31E+06 - - - 0.5018 - 1.565 0.32 - 169.2 1 2 0 0.0006 10 0 0 0 1.55E+07 3.12E+06 - - - 2.6545 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19283.19283.2 0.00271 16-Aug R.LSYPTFFPR.F "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1126.5811 1.49 24310 19283 2 1126.582058 564.2978 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 8.75 3666.7 - 1.16E+06 - - - 0.8228 - 1.601 0.351 - 183.3 1 2 0 0.0009 9 0 0 0 2.19E+07 1.47E+07 - - - 2.9947 1 230117_WJC_METTL3_WT_vs_EV_F03.19286.19286.2 5.63E-05 16-Nov K.LPFPIIDDR.N sp|P30041|PRDX6_HUMAN 1 1084.5917 1.35 24313 19286 2 1085.585058 543.3031 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.21 3667.1 - 659938 - - - 915.8857 - 2.222 0.508 - 391.2 1 2 0 0.9934 9 0 0 0 7.68E+07 5.68E+07 - - - 4.791 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.19289.19289.2 0.00514 18-Jul R.VIEQLLVGLK[136.11].D "sp|Q9BTW9|TBCD_HUMAN,tr|A0A804HJ32|A0A804HJ32_HUMAN,tr|A0A804HKT8|A0A804HKT8_HUMAN,tr|A0A804HHW7|A0A804HHW7_HUMAN,tr|A0A804HL21|A0A804HL21_HUMAN,tr|A0A804HKB9|A0A804HKB9_HUMAN,tr|A0A804HJY5|A0A804HJY5_HUMAN,tr|A0A804HI02|A0A804HI02_HUMAN,tr|A0A804HIU1|A0A804HIU1_HUMAN,tr|A0A804HJ57|A0A804HJ57_HUMAN,tr|A0A804HLF8|A0A804HLF8_HUMAN,tr|A0A804HL62|A0A804HL62_HUMAN,tr|A0A804HIC0|A0A804HIC0_HUMAN,tr|J3KR97|J3KR97_HUMAN,tr|A0A804HI57|A0A804HI57_HUMAN,tr|A0A804HIN6|A0A804HIN6_HUMAN,tr|A0A804HLI2|A0A804HLI2_HUMAN" 17 1118.7154 1.32 24316 19289 2 1118.714449 560.365 Tubulin-specific chaperone D OS=Homo sapiens OX=9606 GN=TBCD PE=1 SV=2 5.97 3667.4 - 519100 - - - -0.8912 - 1.492 0.354 - 98.5 1 2 0 -0.001 10 0 0 0 1.86E+06 1.41E+06 - - - 2.7722 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.19290.19290.2 0.000127 22-Dec R.NIPGITLLNVSK[136.11].L "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1275.7642 -1 24317 19290 2 1275.768019 638.8894 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.75 3667.6 - 371772 - - - 3.0037 - 2.105 0.33 - 389.5 1 2 0 0.0038 12 0 0 0 0.00E+00 0.00E+00 - - - 3.4356 0.8837 230117_WJC_METTL3_WT_vs_EV_F03.19299.19299.2 0.0259 14-Aug R.WALGQVFR.Q "sp|P26572|MGAT1_HUMAN,tr|D6RF69|D6RF69_HUMAN" 2 975.529 1.37 24325 19299 2 976.535164 488.7718 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 9.75 3668.6 - 2.02E+06 - - - 1031.3665 - 1.569 0.332 - 194.8 1 2 0 1.0061 8 0 0 0 6.76E+06 4.95E+06 - - - 2.5357 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19302.19302.2 0.00201 16-Dec K.TLEEILLER.A "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 3 1114.6234 2.36 24328 19302 2 1114.625783 558.319 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.25 3669 - 1.33E+06 - - - 2.1469 - 2.254 0.377 - 406.4 1 2 0 0.0024 9 0 0 0 5.64E+07 2.39E+07 - - - 4.176 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19303.19303.2 0.0419 16-Sep K.LSPEELLLR.W "sp|P13797|PLST_HUMAN,sp|Q14651|PLSI_HUMAN,sp|P13796|PLSL_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|C9JAM8|C9JAM8_HUMAN" 5 1068.6179 2.49 24329 19303 2 1068.620248 535.3162 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.53 3669.1 - 1.21E+06 - - - 2.1879 - 1.683 0.286 - 157.9 1 2 0 0.0023 9 0 0 0 4.45E+07 1.79E+07 - - - 2.6587 0.9781 230117_WJC_METTL3_WT_vs_EV_F03.19308.19308.2 0.132 16-Jul K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 1.63 24334 19308 2 1014.538205 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3669.7 - 546328 - - - 3.578 - 1.701 0.039 - 103.2 4 2 0 0.0036 9 0 0 0 8.38E+06 5.13E+06 - - - 0.5958 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19310.19310.2 0.986 22-Dec K.LILSLEGGYNLR[166.11].A "sp|Q9UBN7|HDAC6_HUMAN,tr|A0A2R8YCS4|A0A2R8YCS4_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 3 1356.7641 0.56 24336 19310 2 1356.766041 679.3893 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 6 3670 - 345593 - - - 1.452 - 2.262 0.356 - 444.6 1 2 0 0.002 12 0 0 0 9.43E+05 1.69E+06 - - - 3.8175 1 230117_WJC_METTL3_WT_vs_EV_F03.19311.19311.2 3.79E-06 17/24 R.TPFTTAQLLALER.K sp|P28360|MSX1_HUMAN 1 1459.8035 1.77 24337 19311 2 1459.806551 730.909 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3670.1 - 336264 - - - 2.1044 - 3.115 0.592 - 1105.5 1 2 0 0.0031 13 0 0 0 1.00E+07 5.65E+06 - - - 6.3287 0.9959 230117_WJC_METTL3_WT_vs_EV_F03.19313.19313.2 0.0091 12-Jul K.LFGELFK[136.11].L "sp|Q15032|R3HD1_HUMAN,tr|A0A804HIA8|A0A804HIA8_HUMAN,tr|H7C207|H7C207_HUMAN" 3 860.4887 1.04 24339 19313 2 860.488892 431.2516 R3H domain-containing protein 1 OS=Homo sapiens OX=9606 GN=R3HDM1 PE=1 SV=3 6 3670.4 - 304463 - - - 0.1755 - 1.611 0.11 - 110.2 1 2 0 0.0002 7 0 0 0 2.71E+06 2.60E+06 - - - 1.3644 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19318.19318.2 0.0413 18-Aug R.LGLDDFESLK.V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1135.5761 0.44 24343 19318 2 1135.578483 568.7953 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3671 - 886358 - - - 2.0941 - 2.166 0.443 - 127.2 1 2 0 0.0024 10 0 0 0 1.97E+07 4.49E+07 - - - 4.4696 1 230117_WJC_METTL3_WT_vs_EV_F03.19322.19322.2 6.32E-06 14/24 R.TPFTTAQLLALER[166.11].K sp|P28360|MSX1_HUMAN 1 1469.8117 1.77 24347 19322 2 1469.813856 735.9132 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3671.4 - 176453 - - - 1.4335 - 2.949 0.556 - 513.5 1 2 0 0.0021 13 0 0 0 1.00E+07 5.65E+06 - - - 5.9226 0.9937 230117_WJC_METTL3_WT_vs_EV_F03.19323.19323.2 0.332 14-Jun K.GVLSDLTK.V "sp|Q8NG11|TSN14_HUMAN,tr|A6NEP9|A6NEP9_HUMAN,tr|H7BXY6|H7BXY6_HUMAN" 3 831.4702 10.82 24348 19323 2 831.469647 416.7424 Tetraspanin-14 OS=Homo sapiens OX=9606 GN=TSPAN14 PE=1 SV=1 5.84 3671.5 - 127935 - - - -0.6446 - 1.426 0.174 - 117.3 1 2 0 -0.0005 8 0 0 0 9.63E+06 8.90E+05 - - - 1.3963 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.19329.19329.2 0.0216 14-May K.LVYVDLLR[166.11].E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 999.5992 2.15 24352 19329 2 999.599804 500.8069 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.84 3672.2 - 1.53E+06 - - - 0.5672 - 1.163 0.248 - 94.5 1 2 0 0.0006 8 0 0 0 1.91E+07 8.87E+06 - - - 1.328 1 230117_WJC_METTL3_WT_vs_EV_F03.19330.19330.2 9.99E-05 14/24 R.ILDIDNVDLAMGK.M sp|O43615|TIM44_HUMAN 1 1415.733 2.62 24353 19330 2 1415.734292 708.8738 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3672.2 - 919732 - - - 0.9006 - 2.641 0.567 - 636.9 1 2 0 0.0013 13 0 0 0 3.10E+07 1.18E+07 - - - 5.721 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19331.19331.2 0.0131 16-Oct K.IPSVLFLGK.L sp|Q8IW75|SPA12_HUMAN 1 972.6008 999 24354 19331 2 972.602874 487.3077 Serpin A12 OS=Homo sapiens OX=9606 GN=SERPINA12 PE=1 SV=1 8.75 3672.3 - 689215 - - - 2.1283 - 1.977 0.376 - 222.7 1 2 0 0.0021 9 0 0 0 6.75E+06 0.00E+00 - - - 3.7893 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.19332.19332.2 0.508 16-Aug K.LSPEELLLR[166.11].W "sp|P13797|PLST_HUMAN,sp|Q14651|PLSI_HUMAN,sp|P13796|PLSL_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|C9JAM8|C9JAM8_HUMAN" 5 1078.6262 2.5 24355 19332 2 1078.627278 540.3204 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.53 3672.4 - 613010 - - - 1.018 - 1.468 0.265 - 157.1 1 2 0 0.0011 9 0 0 0 4.38E+07 1.75E+07 - - - 2.1086 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.19333.19333.2 0.339 18-Aug K.LFLELEPQVR[166.11].D "sp|Q13098|CSN1_HUMAN,tr|A0A096LP07|A0A096LP07_HUMAN,tr|A8K070|A8K070_HUMAN,tr|C9JFE4|C9JFE4_HUMAN,tr|A0A096LPJ3|A0A096LPJ3_HUMAN" 5 1252.7055 1.47 24356 19333 2 1252.705823 627.36 COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4 4.53 3672.5 - 560039 - - - 0.2634 - 1.682 0.241 - 212.7 1 2 0 0.0003 10 0 0 0 6.83E+06 4.64E+06 - - - 2.2724 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19334.19334.2 0.0132 20-Sep R.LLGLGVTDFSR[166.11].A "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 1186.6585 0.93 24357 19334 2 1186.660865 594.3365 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 5.84 3672.5 - 557917 - - - 1.9568 - 1.83 0.39 - 190.6 1 2 0 0.0023 11 0 0 0 4.72E+06 5.05E+06 - - - 3.5556 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.19335.19335.2 0.0238 12-Jun R.SGMFWLR[166.11].F sp|P31930|QCR1_HUMAN 1 905.4457 1.29 24358 19335 2 905.446904 453.7301 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 9.47 3672.6 - 444460 - - - 1.3143 - 1.322 0.314 - 131.6 1 2 0 0.0012 7 0 0 0 5.06E+06 3.92E+06 - - - 2.2443 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.19337.19337.2 0.0297 14-Aug K.ELEPFLLR[166.11].R sp|O14646|CHD1_HUMAN 1 1025.5785 0.77 24360 19337 2 1025.58268 513.7965 Chromodomain-helicase-DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=CHD1 PE=1 SV=2 4.53 3672.9 - 373212 - - - 4.0738 - 1.605 0.272 - 259.2 1 2 0 0.0042 8 0 0 0 2.27E+06 2.97E+06 - - - 2.4756 0.9928 230117_WJC_METTL3_WT_vs_EV_F03.19338.19338.2 0.312 18-Jul R.LLLQIPSTIR[166.11].S sp|Q16394|EXT1_HUMAN 1 1162.7313 1.02 24361 19338 2 1162.736236 582.3729 Exostosin-1 OS=Homo sapiens OX=9606 GN=EXT1 PE=1 SV=2 9.75 3673 - 249321 - - - 4.2331 - 1.677 0.183 - 143.8 1 2 0 0.0049 10 0 0 0 2.34E+06 2.30E+06 - - - 1.8342 1 230117_WJC_METTL3_WT_vs_EV_F03.19339.19339.2 5.31E-07 14/24 R.ILDIDNVDLAMGK[136.11].M sp|O43615|TIM44_HUMAN 1 1423.7472 2.62 24362 19339 2 1423.745008 712.8809 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3673.1 - 229750 - - - -1.5515 - 2.743 0.451 - 642.5 1 2 0 -0.0022 13 0 0 0 3.10E+07 1.18E+07 - - - 4.9612 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19342.19342.2 0.00103 24-Aug R.IITLAGPTNAIFK.A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1357.7969 2.5 24363 19342 2 1357.80129 679.9057 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3673.5 - 686671 - - - 3.2059 - 1.539 0.513 - 195.7 1 2 0 0.0044 13 0 0 0 2.63E+08 1.05E+08 - - - 3.9352 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19343.19343.2 3.37E-06 16-Sep K.DVDLEFLAK[136.11].M "sp|P55072|TERA_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN" 6 1056.5583 0.84 24364 19343 2 1056.560609 529.2864 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.03 3673.6 - 453352 - - - 2.2072 - 1.724 0.32 - 214.3 1 2 0 0.0023 9 0 0 0 1.05E+07 1.24E+07 - - - 2.9795 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19345.19345.2 0.103 18-Oct K.SLLFVNTLER[166.11].S "sp|Q9NY93|DDX56_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1200.6742 0.64 24366 19345 2 1200.676531 601.3444 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 5.72 3673.7 - 613182 - - - 1.9472 - 2.071 0.363 - 388.3 1 2 0 0.0023 10 0 0 0 1.07E+07 1.65E+07 - - - 3.7535 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19346.19346.2 0.0483 12-Jul R.SGMFWLR.F sp|P31930|QCR1_HUMAN 1 895.4374 1.29 24367 19346 2 895.438365 448.726 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 9.47 3673.8 - 535339 - - - 1.0285 - 1.617 0.403 - 242.4 1 2 0 0.0009 7 0 0 0 5.06E+06 3.92E+06 - - - 3.54 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19348.19348.2 0.000614 16-Sep R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 4.28 24369 19348 2 1006.57181 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3674 - 226792 - - - 1.8995 - 1.803 0.466 - 204.5 1 2 0 0.0019 9 0 0 0 7.17E+06 1.68E+06 - - - 4.1876 1 230117_WJC_METTL3_WT_vs_EV_F03.19351.19351.2 5.31E-06 16/20 K.ILEAVTLVQLK.E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1225.7646 0.85 24372 19351 2 1225.766179 613.8896 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6 3674.3 - 309616 - - - 1.3086 - 2.876 0.417 - 629.9 1 2 0 0.0016 11 0 0 0 1.06E+07 1.25E+07 - - - 4.9783 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.19354.19354.2 0.00687 28-Jun R.VLVVGAGGIGC[160.03]ELLK[136.11].N "sp|Q9UBT2|SAE2_HUMAN,tr|U3KQ55|U3KQ55_HUMAN,tr|K7EPL2|K7EPL2_HUMAN,tr|K7ES38|K7ES38_HUMAN" 4 1491.8574 -1 24375 19354 2 1491.86092 746.936 SUMO-activating enzyme subunit 2 OS=Homo sapiens OX=9606 GN=UBA2 PE=1 SV=2 5.97 3674.7 - 97616.3 - - - 2.3353 - 1.438 0.306 - 42 2 2 0 0.0035 15 0 0 0 0.00E+00 0.00E+00 - - - 2.0586 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19359.19359.2 0.0327 22-Aug R.GILLFGPPGTGK.S "sp|Q9UN37|VPS4A_HUMAN,sp|O75351|VPS4B_HUMAN,sp|Q6PIW4|FIGL1_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 4 1155.6652 4.19 24379 19359 2 1155.666911 578.8399 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 8.75 3675.3 - 668124 - - - 1.4849 - 1.958 0.293 - 134 1 2 0 0.0017 12 0 0 0 4.96E+06 1.18E+06 - - - 2.9725 0.9932 230117_WJC_METTL3_WT_vs_EV_F03.19360.19360.2 0.319 14-Aug R.LPLFGLGR[166.11].L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 881.5362 1.34 24380 19360 2 881.539397 441.7754 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3675.4 - 2.03E+06 - - - 3.5778 - 1.494 0.169 - 319.2 1 2 0 0.0032 8 0 0 0 1.03E+08 7.65E+07 - - - 1.499 0.997 230117_WJC_METTL3_WT_vs_EV_F03.19361.19361.2 0.528 14-Oct R.LPLFGLGR.L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 871.528 1.34 24381 19361 2 871.530417 436.7713 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3675.6 - 1.57E+06 - - - 2.8043 - 1.761 0.143 - 453 1 2 0 0.0024 8 0 0 0 1.03E+08 7.65E+07 - - - 1.8031 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.19362.19362.2 0.00426 20-Oct K.ILEAVTLVQLK[136.11].E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1233.7788 0.85 24382 19362 2 1233.783349 617.8967 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6 3675.7 - 1.43E+06 - - - 3.7073 - 2.231 0.422 - 236.3 1 2 0 0.0046 11 0 0 0 1.06E+07 1.25E+07 - - - 4.3273 0.999 230117_WJC_METTL3_WT_vs_EV_F03.19363.19363.2 0.000408 16-Oct K.WQALLVQIR[166.11].K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1135.6741 0.89 24383 19363 2 1135.677619 568.8443 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.75 3675.8 - 1.12E+06 - - - 3.0687 - 2.011 0.277 - 386 1 2 0 0.0035 9 0 0 0 1.20E+07 1.35E+07 - - - 3.107 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.19365.19365.2 0.0417 22-Sep K.LILISTNGSFIR[166.11].L sp|Q6UXN9|WDR82_HUMAN 1 1342.7848 0.95 24385 19365 2 1342.789923 672.3997 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 9.75 3676.1 - 545107 - - - 3.8107 - 1.735 0.309 - 241.9 1 2 0 0.0051 12 0 0 0 9.32E+06 9.77E+06 - - - 2.7715 0.999 230117_WJC_METTL3_WT_vs_EV_F03.19366.19366.2 0.031 16-Sep R.VVVLGLLPR.G "sp|Q15102|PA1B3_HUMAN,tr|M0R389|M0R389_HUMAN" 2 964.6433 1.19 24386 19366 2 964.646166 483.3289 Platelet-activating factor acetylhydrolase IB subunit alpha1 OS=Homo sapiens OX=9606 GN=PAFAH1B3 PE=1 SV=1 9.72 3676.2 - 419858 - - - 2.9327 - 1.962 0.273 - 291.9 1 2 0 0.0028 9 0 0 0 3.52E+06 2.95E+06 - - - 3.0063 1 230117_WJC_METTL3_WT_vs_EV_F03.19368.19368.2 2.01E-06 26-Dec R.WTTEEQLLAVQAIR.K sp|Q9UKL0|RCOR1_HUMAN 1 1656.8835 4.1 24388 19368 2 1656.890544 829.449 REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2 4.53 3676.5 - 243907 - - - 4.2387 - 2.788 0.557 - 490.2 1 2 0 0.007 14 0 0 0 1.96E+06 4.77E+05 - - - 5.7258 0.9688 230117_WJC_METTL3_WT_vs_EV_F03.19375.19375.2 3.89 24-Jun R.IITLAGPTNAIFK[136.11].A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1365.8111 2.5 24393 19375 2 1365.810893 683.9128 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3677.4 - 1.22E+07 - - - -0.1786 - 1.213 0.084 - 85.3 2 2 0 -0.0002 13 0 0 0 2.63E+08 1.05E+08 - - - 0.0225 1 230117_WJC_METTL3_WT_vs_EV_F03.19376.19376.2 0.00735 22-Nov K.LILISTNGSFIR.L sp|Q6UXN9|WDR82_HUMAN 1 1332.7765 0.95 24394 19376 2 1332.781553 667.3955 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 9.75 3677.6 - 1.54E+06 - - - 3.7643 - 2.367 0.463 - 408.1 1 2 0 0.005 12 0 0 0 9.32E+06 9.77E+06 - - - 4.7262 0.9957 230117_WJC_METTL3_WT_vs_EV_F03.19377.19377.2 0.0388 16-Nov R.MADLSELLK.E "sp|P30519|HMOX2_HUMAN,tr|I3L276|I3L276_HUMAN,tr|I3L159|I3L159_HUMAN,tr|I3L463|I3L463_HUMAN,tr|I3L4P8|I3L4P8_HUMAN,tr|A0A1B0GXH0|A0A1B0GXH0_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 8 1018.5369 1.49 24395 19377 2 1018.541705 510.2757 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 4.37 3677.7 - 1.63E+06 - - - 4.7342 - 1.783 0.273 - 402.4 1 2 0 0.0048 9 0 0 0 8.81E+06 5.90E+06 - - - 2.7289 1 230117_WJC_METTL3_WT_vs_EV_F03.19378.19378.2 4.66E-06 20-Dec K.LWDLASGTLYK[136.11].E sp|O75529|TAF5L_HUMAN 1 1273.6798 1.21 24396 19378 2 1273.686188 637.8472 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 5.83 3677.8 - 1.27E+06 - - - 5.024 - 2.307 0.536 - 456.5 1 2 0 0.0064 11 0 0 0 1.16E+07 9.62E+06 - - - 5.2593 0.9771 230117_WJC_METTL3_WT_vs_EV_F03.19379.19379.2 0.0923 16-Sep R.MADLSELLK[136.11].E "sp|P30519|HMOX2_HUMAN,tr|I3L276|I3L276_HUMAN,tr|I3L159|I3L159_HUMAN,tr|I3L463|I3L463_HUMAN,tr|I3L4P8|I3L4P8_HUMAN,tr|A0A1B0GXH0|A0A1B0GXH0_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 8 1026.5511 1.49 24397 19379 2 1026.555496 514.2828 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 4.37 3678 - 1.15E+06 - - - 4.2989 - 1.532 0.087 - 177.3 1 2 0 0.0044 9 0 0 0 8.81E+06 5.90E+06 - - - 0.9163 1 230117_WJC_METTL3_WT_vs_EV_F03.19380.19380.2 1.53E-05 18-Oct R.VLALEILPER[166.11].V sp|Q56A73|SPIN4_HUMAN 1 1161.6997 0.58 24398 19380 2 1161.70443 581.8571 Spindlin-4 OS=Homo sapiens OX=9606 GN=SPIN4 PE=1 SV=1 4.53 3678.1 - 767583 - - - 4.0888 - 2.247 0.471 - 344.5 1 2 0 0.0047 10 0 0 0 2.48E+06 4.26E+06 - - - 4.7781 0.9925 230117_WJC_METTL3_WT_vs_EV_F03.19381.19381.2 0.124 16-Sep K.NLLNLDVIK.K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1040.623 0.93 24399 19381 2 1040.62809 521.3188 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3678.2 - 640804 - - - 4.8951 - 1.784 0.205 - 241.8 1 2 0 0.0051 9 0 0 0 1.65E+07 1.78E+07 - - - 2.2282 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19382.19382.2 0.00135 22-Dec K.QVVPFVYQTIVK[136.11].D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1427.8268 1.96 24400 19382 2 1427.83112 714.9207 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 3678.3 - 640597 - - - 3.034 - 2.197 0.47 - 432.2 1 2 0 0.0043 12 0 0 0 7.99E+06 4.08E+06 - - - 4.582 0.9771 230117_WJC_METTL3_WT_vs_EV_F03.19383.19383.2 1.52 26-Jul K.VVIGMDVAASEFYR.N "sp|P13929|ENOB_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN" 2 1555.7705 2.04 24401 19383 2 1555.774524 778.8925 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.37 3678.5 - 636436 - - - 2.609 - 1.095 0.121 - 102.3 1 2 0 0.0041 14 0 0 0 2.70E+07 1.32E+07 - - - 0.1612 0.9954 230117_WJC_METTL3_WT_vs_EV_F03.19384.19384.2 0.0066 18-Aug R.VLALEILPER.V sp|Q56A73|SPIN4_HUMAN 1 1151.6914 0.56 24402 19384 2 1151.697576 576.853 Spindlin-4 OS=Homo sapiens OX=9606 GN=SPIN4 PE=1 SV=1 4.53 3678.6 - 509466 - - - 5.3539 - 1.933 0.309 - 199.1 1 2 0 0.0062 10 0 0 0 2.53E+06 4.51E+06 - - - 3.161 0.9857 230117_WJC_METTL3_WT_vs_EV_F03.19385.19385.2 0.0756 14-Jul R.LWLLDDSK.T "sp|O43639|NCK2_HUMAN,sp|P16333|NCK1_HUMAN,tr|E7EPF5|E7EPF5_HUMAN,tr|E7ERP6|E7ERP6_HUMAN,tr|C9J0K5|C9J0K5_HUMAN,tr|C9K098|C9K098_HUMAN,tr|C9J869|C9J869_HUMAN,tr|C9JVV5|C9JVV5_HUMAN,tr|E9PEE2|E9PEE2_HUMAN,tr|H7C5C7|H7C5C7_HUMAN" 10 988.5229 1.23 24403 19385 2 988.527999 495.2687 Cytoplasmic protein NCK2 OS=Homo sapiens OX=9606 GN=NCK2 PE=1 SV=2 4.21 3678.7 - 456921 - - - 5.1107 - 1.647 0.164 - 129.5 1 2 0 0.0051 8 0 0 0 2.55E+06 2.07E+06 - - - 1.7555 1 230117_WJC_METTL3_WT_vs_EV_F03.19389.19389.2 0.000121 22-Nov K.LFGYEPTIYYPK[136.11].R "sp|Q8NCW5|NNRE_HUMAN,tr|A0A7P0Z426|A0A7P0Z426_HUMAN,tr|Q5T3I4|Q5T3I4_HUMAN,tr|A0A7P0T9Y2|A0A7P0T9Y2_HUMAN,tr|A0A7P0TAG8|A0A7P0TAG8_HUMAN,tr|Q5T3I3|Q5T3I3_HUMAN" 6 1497.7635 1.92 24407 19389 2 1497.768156 749.889 NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2 6 3679.3 - 309970 - - - 3.0959 - 2.249 0.536 - 322.2 1 2 0 0.0046 12 0 0 0 5.63E+06 2.93E+06 - - - 5.131 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.19390.19390.2 5.48E-05 14/24 R.VESPVLPPVLVPR.H "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN" 2 1400.8391 1.87 24408 19390 2 1400.84524 701.4268 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 5.97 3679.4 - 321532 - - - 4.3567 - 1.923 0.449 - 463.2 1 2 0 0.0061 13 0 0 0 2.17E+06 1.16E+06 - - - 4.0336 1 230117_WJC_METTL3_WT_vs_EV_F03.19392.19392.2 7.13E-07 15/26 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 -1 24410 19392 2 1541.850159 771.9299 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3679.6 - 144396 - - - 3.1229 - 2.799 0.481 - 784.7 1 2 0 0.0048 14 0 0 0 0.00E+00 0.00E+00 - - - 5.175 1 230117_WJC_METTL3_WT_vs_EV_F03.19397.19397.2 3.71E-06 20-Dec K.LGGNEIVSFLK.G "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 4 1175.655 3.37 24414 19397 2 1175.660218 588.8348 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6 3680.3 - 1.66E+06 - - - 4.418 - 2.45 0.478 - 374.2 1 2 0 0.0052 11 0 0 0 2.32E+07 6.89E+06 - - - 4.994 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.19400.19400.2 0.00765 16-Oct K.NLLNLDVIK[136.11].K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1048.6372 0.93 24417 19400 2 1048.640524 525.3259 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3680.4 - 2.40E+06 - - - 3.1736 - 1.988 0.284 - 330.7 1 2 0 0.0033 9 0 0 0 1.65E+07 1.78E+07 - - - 3.1255 1 230117_WJC_METTL3_WT_vs_EV_F03.19401.19401.2 2.25E-06 22-Dec K.QVVPFVYQTIVK.D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1419.8126 1.96 24418 19401 2 1419.8158 710.9136 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 3680.6 - 744522 - - - 2.2623 - 2.382 0.52 - 511.4 1 2 0 0.0032 12 0 0 0 7.99E+06 4.08E+06 - - - 5.1644 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.19402.19402.2 0.0562 14-Aug R.LWDFIENR.E "sp|Q9H000|MKRN2_HUMAN,tr|A0A7I2V5D2|A0A7I2V5D2_HUMAN,tr|A0A7I2YQI0|A0A7I2YQI0_HUMAN,tr|C9J494|C9J494_HUMAN" 4 1091.54 1.76 24419 19402 2 1091.541579 546.7773 Probable E3 ubiquitin-protein ligase makorin-2 OS=Homo sapiens OX=9606 GN=MKRN2 PE=1 SV=2 4.37 3680.7 - 636771 - - - 1.4521 - 1.854 0.238 - 219.4 1 2 0 0.0016 8 0 0 0 9.88E+06 5.62E+06 - - - 2.6603 0.9961 230117_WJC_METTL3_WT_vs_EV_F03.19404.19404.2 0.322 12-Jul K.FDLIWNR.A "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|H0YEW4|H0YEW4_HUMAN,tr|A8MRA7|A8MRA7_HUMAN,tr|H0YD21|H0YD21_HUMAN" 5 962.4974 1.69 24421 19404 2 962.499378 482.256 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 5.84 3681 - 374031 - - - 2.054 - 1.715 0.07 - 202.4 1 2 0 0.002 7 0 0 0 2.06E+06 1.22E+06 - - - 1.2666 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19406.19406.3 0.00045 13/48 R.IITLAGPTNAIFK.A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1357.7969 1.19 24423 19406 3 1357.800465 453.6063 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3681.2 - 278497 - - - 2.5983 - 2.263 0.324 - 213.1 1 2 0 0.0035 13 0 0 0 1.78E+06 1.50E+06 - - - 4.3656 0.9657 230117_WJC_METTL3_WT_vs_EV_F03.19407.19407.2 0.00131 16-Sep L.GVLASDLQR[166.11].V "sp|O15381|NVL_HUMAN,tr|E9PH71|E9PH71_HUMAN,tr|F8WF01|F8WF01_HUMAN,tr|E7EWK7|E7EWK7_HUMAN,tr|E9PGD8|E9PGD8_HUMAN" 5 967.5326 0.61 24424 19407 2 967.534046 484.7736 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 5.84 3681.3 - 257194 - - - 1.4801 - 1.856 0.347 - 219.6 1 1 0 0.0014 9 0 0 0 1.69E+06 2.77E+06 - - - 3.3926 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.19408.19408.2 0.0389 16-Jul R.VVVLGLLPR[166.11].G "sp|Q15102|PA1B3_HUMAN,tr|M0R389|M0R389_HUMAN" 2 974.6516 1.21 24425 19408 2 974.654432 488.3331 Platelet-activating factor acetylhydrolase IB subunit alpha1 OS=Homo sapiens OX=9606 GN=PAFAH1B3 PE=1 SV=1 9.72 3681.5 - 230152 - - - 2.8985 - 1.4 0.238 - 122.6 1 2 0 0.0028 9 0 0 0 3.57E+06 2.95E+06 - - - 1.7714 0.9729 230117_WJC_METTL3_WT_vs_EV_F03.19409.19409.2 0.0119 12-Jul R.YVLSFLR.T "sp|Q96SI1|KCD15_HUMAN,tr|V9GYY8|V9GYY8_HUMAN,tr|K7EN63|K7EN63_HUMAN" 3 896.512 1.09 24426 19409 2 896.516444 449.2633 BTB\POZ domain-containing protein KCTD15 OS=Homo sapiens OX=9606 GN=KCTD15 PE=1 SV=1 8.75 3681.6 - 181980 - - - 4.9693 - 1.399 0.14 - 200.9 1 2 0 0.0045 7 0 0 0 3.25E+06 2.99E+06 - - - 1.1375 1 230117_WJC_METTL3_WT_vs_EV_F03.19411.19411.2 4.89E-08 13/20 K.VGEVTYVELFK[136.11].D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1290.6951 1.84 24427 19411 2 1290.698243 646.3548 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.53 3681.9 - 2.53E+06 - - - 2.4312 - 2.75 0.592 - 821.1 1 2 0 0.0031 11 0 0 0 5.72E+07 3.10E+07 - - - 6.1491 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.19412.19412.2 0.047 12-Jul K.LYSLLFR[166.11].R sp|Q9UDW1|QCR9_HUMAN 1 920.5359 1.18 24428 19412 2 920.538032 461.2752 Cytochrome b-c1 complex subunit 9 OS=Homo sapiens OX=9606 GN=UQCR10 PE=1 SV=3 8.75 3682 - 387652 - - - 2.3063 - 1.321 0.249 - 131.5 1 2 0 0.0021 7 0 0 0 7.71E+06 6.53E+06 - - - 1.7615 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19415.19415.2 0.000184 22-Dec K.VVLEGPAPWGFR.L "sp|Q9NR12|PDLI7_HUMAN,tr|D6RF83|D6RF83_HUMAN,tr|D6RAN1|D6RAN1_HUMAN,tr|H7BYK4|H7BYK4_HUMAN,tr|D6RH06|D6RH06_HUMAN" 5 1326.7085 5.7 24431 19415 2 1326.712454 664.3615 PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1 5.97 3682.3 - 660694 - - - 3.0127 - 2.043 0.389 - 466.5 1 2 0 0.004 12 0 0 0 7.25E+06 1.27E+06 - - - 3.7927 0.956 230117_WJC_METTL3_WT_vs_EV_F03.19418.19418.2 3.33 18-May R.AQADEVLQLR.E "sp|O60437|PEPL_HUMAN,tr|K7EKI8|K7EKI8_HUMAN,tr|K7EQ71|K7EQ71_HUMAN" 3 1141.6091 2.92 24434 19418 2 1141.61131 571.8118 Periplakin OS=Homo sapiens OX=9606 GN=PPL PE=1 SV=4 4.37 3682.7 - 422100 - - - 1.9035 - 1.229 0.04 - 61.1 7 2 0 0.0022 10 0 0 0 1.72E+07 5.90E+06 - - - -0.4662 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.19423.19423.2 0.000894 16-Aug K.SIVLVSFVR.S "sp|P51530|DNA2_HUMAN,tr|F8VR31|F8VR31_HUMAN,tr|H0Y455|H0Y455_HUMAN" 3 1018.6175 6.55 24439 19423 2 1018.619023 510.316 DNA replication ATP-dependent helicase\nuclease DNA2 OS=Homo sapiens OX=9606 GN=DNA2 PE=1 SV=3 9.47 3683.3 - 283395 - - - 1.4795 - 1.776 0.162 - 154.4 1 2 0 0.0015 9 0 0 0 2.11E+06 3.22E+05 - - - 1.8987 0.8671 230117_WJC_METTL3_WT_vs_EV_F03.19424.19424.2 0.185 12-Jul L.PLFGLGR.L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 758.4439 3.17 24440 19424 2 758.445045 380.2292 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 10.18 3683.4 - 254010 - - - 1.4978 - 1.404 0.222 - 189 1 1 0 0.0011 7 0 0 0 4.45E+06 1.40E+06 - - - 1.7555 1 230117_WJC_METTL3_WT_vs_EV_F03.19425.19425.2 1.66E-08 24-Nov K.LVDSMGWELASVR[166.11].R "sp|O94761|RECQ4_HUMAN,tr|A0A087WTJ0|A0A087WTJ0_HUMAN,tr|A0A087X072|A0A087X072_HUMAN" 3 1471.7369 1.26 24441 19425 2 1471.729372 736.8757 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.37 3683.6 - 235611 - - - -5.0947 - 2.53 0.594 - 349.3 1 2 0 -0.0075 13 0 0 0 1.77E+06 1.40E+06 - - - 5.8082 1 230117_WJC_METTL3_WT_vs_EV_F03.19427.19427.2 4.04E-08 15/28 R.VGPDVVTDPAFLVTR[166.11].S sp|Q9NV31|IMP3_HUMAN 1 1594.8594 1.52 24443 19427 2 1594.863925 798.437 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3683.8 - 224636 - - - 2.8197 - 2.268 0.599 - 510.1 1 2 0 0.0045 15 0 0 0 5.54E+06 3.64E+06 - - - 5.4771 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.19430.19430.2 0.0115 24-Sep R.VESPVLPPVLVPR[166.11].H "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN" 2 1410.8474 1.87 24446 19430 2 1410.850491 706.431 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 5.97 3684.2 - 153892 - - - 2.1859 - 1.361 0.361 - 183.1 1 2 0 0.0031 13 0 0 0 2.17E+06 1.16E+06 - - - 2.4974 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.19434.19434.2 7.12E-06 20-Nov R.LLESLDQLELR.V sp|O95816|BAG2_HUMAN 1 1327.7347 8.95 24449 19434 2 1327.740201 664.8746 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.14 3684.6 - 1.67E+06 - - - 4.1198 - 2.295 0.407 - 424.6 1 2 0 0.0055 11 0 0 0 2.05E+08 2.29E+07 - - - 4.2927 1 230117_WJC_METTL3_WT_vs_EV_F03.19435.19435.2 4.46E-05 15/28 R.VGPDVVTDPAFLVTR.S sp|Q9NV31|IMP3_HUMAN 1 1584.8512 1.52 24450 19435 2 1584.855357 793.4329 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3684.7 - 357635 - - - 2.6495 - 2.534 0.573 - 527.5 1 2 0 0.0042 15 0 0 0 5.54E+06 3.64E+06 - - - 5.5578 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19438.19438.2 0.0011 24-Dec R.LSAYVSYGGLLMR.L "sp|P52434|RPAB3_HUMAN,tr|C9JLU1|C9JLU1_HUMAN" 2 1428.7435 1.37 24453 19438 2 1428.743711 715.379 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4" 8.59 3685 - 231380 - - - 0.1323 - 2.305 0.413 - 430.3 1 2 0 0.0002 13 0 0 0 3.44E+06 2.51E+06 - - - 4.2346 0.9967 230117_WJC_METTL3_WT_vs_EV_F03.19439.19439.2 0.00747 12-Jul R.EFEFLMR.Q sp|P85037|FOXK1_HUMAN 1 970.4582 3.16 24454 19439 2 970.461204 486.2364 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 4.53 3685.1 - 220369 - - - 3.0553 - 1.349 0.252 - 192.1 1 2 0 0.003 7 0 0 0 2.92E+06 9.23E+05 - - - 1.8499 1 230117_WJC_METTL3_WT_vs_EV_F03.19444.19444.2 1.98E-06 13/26 K.LLDAVDTYIPVPAR[166.11].D sp|P49411|EFTU_HUMAN 1 1551.8536 3.41 24457 19444 2 1551.856622 776.9341 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3685.7 - 2.76E+06 - - - 1.9383 - 2.645 0.602 - 602.2 1 2 0 0.003 14 0 0 0 9.49E+07 2.78E+07 - - - 5.9273 1 230117_WJC_METTL3_WT_vs_EV_F03.19446.19446.3 2.29E-07 14/52 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 3.33 24459 19446 3 1541.848385 514.9557 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3685.9 - 1.70E+06 - - - 1.9723 - 2.758 0.535 - 181.7 1 2 0 0.003 14 0 0 0 1.45E+07 4.35E+06 - - - 7.2 1 230117_WJC_METTL3_WT_vs_EV_F03.19449.19449.2 8.71E-07 22-Nov R.LLTWVIGTGSPR[166.11].L sp|Q92616|GCN1_HUMAN 1 1308.7429 1.37 24462 19449 2 1308.745658 655.3787 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.75 3686.1 - 839110 - - - 2.0753 - 2.575 0.502 - 515 1 2 0 0.0027 12 0 0 0 4.94E+06 3.60E+06 - - - 5.2366 1 230117_WJC_METTL3_WT_vs_EV_F03.19450.19450.2 0.00149 13/22 R.LLTWVIGTGSPR.L sp|Q92616|GCN1_HUMAN 1 1298.7347 1.37 24463 19450 2 1298.738094 650.3746 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.75 3686.2 - 838777 - - - 2.6349 - 2.244 0.475 - 243.8 1 2 0 0.0034 12 0 0 0 4.94E+06 3.60E+06 - - - 4.6749 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19452.19452.2 0.0912 18-Dec R.AEVVSLLLDR[166.11].K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1123.6476 1.23 24465 19452 2 1123.648675 562.8311 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3686.3 - 655402 - - - 0.9175 - 2.31 0.332 - 736 1 2 0 0.001 10 0 0 0 4.62E+07 3.74E+07 - - - 3.8298 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19456.19456.2 4.82E-05 22-Oct R.ELYLEDSPLELK.L sp|Q8TEM1|PO210_HUMAN 1 1447.7446 3.25 24469 19456 2 1447.749009 724.8796 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4 3686.8 - 322166 - - - 3.0268 - 2.181 0.469 - 262.7 1 2 0 0.0044 12 0 0 0 3.27E+06 1.01E+06 - - - 4.5554 1 230117_WJC_METTL3_WT_vs_EV_F03.19457.19457.2 0.000109 20-Nov K.IDAELVLPTIR[166.11].S "sp|O95985|TOP3B_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 2 1248.7317 0.98 24470 19457 2 1248.734863 625.3731 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 4.37 3686.9 - 304759 - - - 2.5266 - 2.492 0.547 - 666.3 1 2 0 0.0032 11 0 0 0 2.75E+06 2.81E+06 - - - 5.5503 1 230117_WJC_METTL3_WT_vs_EV_F03.19458.19458.2 1.28E-07 20-Dec K.IDAELVLPTIR.S "sp|O95985|TOP3B_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 2 1238.7234 0.86 24471 19458 2 1238.728389 620.369 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 4.37 3687 - 204399 - - - 3.9969 - 2.572 0.427 - 434.3 1 2 0 0.005 11 0 0 0 2.30E+06 2.67E+06 - - - 4.7489 0.9969 230117_WJC_METTL3_WT_vs_EV_F03.19462.19462.2 4.33E-05 18-Aug R.AEVVSLLLDR.K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1113.6394 1.23 24473 19462 2 1113.645601 557.827 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3687.6 - 664434 - - - 5.5916 - 2.001 0.432 - 258 1 2 0 0.0062 10 0 0 0 4.62E+07 3.74E+07 - - - 4.166 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.19466.19466.2 0.127 18-Aug K.IELFADVVPK[136.11].T "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 1137.6525 1.8 24477 19466 2 1137.655631 569.8335 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.37 3687.9 - 580129 - - - 2.7425 - 1.724 0.207 - 114.3 2 2 0 0.0031 10 0 0 0 7.23E+07 4.02E+07 - - - 1.9547 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.19472.19472.2 3.66E-05 22-Nov K.FATEDEAWAFVR.K sp|O60930|RNH1_HUMAN 1 1440.6674 1.2 24483 19472 2 1440.674155 721.341 Ribonuclease H1 OS=Homo sapiens OX=9606 GN=RNASEH1 PE=1 SV=2 4.14 3688.7 - 115381 - - - 4.7027 - 2.058 0.464 - 384.1 1 2 0 0.0068 12 0 0 0 2.44E+06 2.03E+06 - - - 4.365 1 230117_WJC_METTL3_WT_vs_EV_F03.19473.19473.2 0.0192 13/20 R.VLITTLITAGR[166.11].L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1166.7262 0.91 24484 19473 2 1166.73145 584.3704 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3688.9 - 103471 - - - 4.4749 - 2.597 0.432 - 514.5 1 2 0 0.0052 11 0 0 0 1.16E+07 1.27E+07 - - - 4.8119 1 230117_WJC_METTL3_WT_vs_EV_F03.19475.19475.2 9.19E-05 13/26 R.LIVVLEGASLETVK[136.11].V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1477.8847 1.09 24486 19475 2 1477.88707 739.9496 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3689.1 - 77690.3 - - - 1.6063 - 2.78 0.456 - 471.5 1 2 0 0.0024 14 0 0 0 3.52E+06 3.22E+06 - - - 4.9741 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19476.19476.2 0.000752 22-Oct R.SQPAILLLTAAR.D "sp|Q5JTV8|TOIP1_HUMAN,tr|H0Y4R4|H0Y4R4_HUMAN,tr|J3KN66|J3KN66_HUMAN,tr|A0A0A0MSK5|A0A0A0MSK5_HUMAN" 4 1252.7503 1.61 24487 19476 2 1252.752444 627.3824 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=2 9.47 3689.2 - 66989.6 - - - 1.6939 - 1.981 0.37 - 328.1 1 2 0 0.0021 12 0 0 0 3.67E+06 2.29E+06 - - - 3.5718 0.8621 230117_WJC_METTL3_WT_vs_EV_F03.19481.19481.2 3.71 14-May R.VPGTLLPR[166.11].L sp|Q96BJ3|AIDA_HUMAN 1 861.5312 1.25 24491 19481 2 861.532789 431.7729 "Axin interactor, dorsalization-associated protein OS=Homo sapiens OX=9606 GN=AIDA PE=1 SV=1" 9.72 3689.9 - 2.56E+06 - - - 1.8931 - 0.989 0.01 - 97 5 2 0 0.0016 8 0 0 0 2.67E+07 2.13E+07 - - - -1.2312 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.19484.19484.2 0.00362 16-Oct K.TFDPYIIIR[166.11].A sp|Q13601|KRR1_HUMAN 1 1146.6313 0.001 24494 19484 2 1146.633066 574.3229 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 5.5 3690 - 2.06E+06 - - - 1.5698 - 1.878 0.138 - 359.9 1 2 0 0.0018 9 0 0 0 0.00E+00 1.56E+07 - - - 1.8829 0.8517 230117_WJC_METTL3_WT_vs_EV_F03.19486.19486.2 0.736 14-Jul S.GVLSSIGK[136.11].L "sp|Q9NZJ7|MTCH1_HUMAN,tr|H0Y8C3|H0Y8C3_HUMAN,tr|H7C196|H7C196_HUMAN" 3 767.4633 0.94 24496 19486 2 767.463487 384.7389 Mitochondrial carrier homolog 1 OS=Homo sapiens OX=9606 GN=MTCH1 PE=1 SV=1 8.75 3690.1 - 1.54E+06 - - - 0.3036 - 1.321 0.267 - 169.4 1 1 0 0.0002 8 0 0 0 7.37E+06 7.82E+06 - - - 1.8526 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19488.19488.2 0.000867 20-Nov R.VLITTLITAGR.L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1156.718 0.91 24498 19488 2 1156.71889 579.3663 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3690.2 - 1.40E+06 - - - 0.8049 - 2.183 0.396 - 387.9 1 2 0 0.0009 11 0 0 0 1.16E+07 1.27E+07 - - - 4.0775 0.96 230117_WJC_METTL3_WT_vs_EV_F03.19489.19489.2 6.89 20-Aug K.LGLDIEIATYR.R "sp|Q9NSB2|KRT84_HUMAN,sp|Q14533|KRT81_HUMAN,sp|P78386|KRT85_HUMAN,sp|Q9NSB4|KRT82_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|F5GYI5|F5GYI5_HUMAN" 8 1262.6871 12.06 24499 19489 2 1262.688537 632.3508 "Keratin, type II cuticular Hb4 OS=Homo sapiens OX=9606 GN=KRT84 PE=2 SV=2" 4.37 3690.3 - 1.31E+06 - - - 1.1753 - 1.02 0.062 - 111.1 1 2 0 0.0015 11 0 0 0 2.04E+07 1.69E+06 - - - -0.448 0.9954 230117_WJC_METTL3_WT_vs_EV_F03.19490.19490.2 3.1 18-Jun R.LIESLFTIQK[136.11].M "sp|Q12789|TF3C1_HUMAN,tr|H3BU37|H3BU37_HUMAN" 2 1198.7053 1.24 24500 19490 2 1198.706845 600.3599 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 6 3690.3 - 952098 - - - 1.3097 - 1.071 0.244 - 72.9 1 2 0 0.0016 10 0 0 0 6.55E+06 5.27E+06 - - - 1.0342 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19491.19491.2 0.00469 16-Aug K.GLMVLELPK.R "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 998.5834 3.18 24501 19491 2 998.582885 500.299 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6 3690.4 - 903473 - - - -0.5548 - 1.539 0.413 - 240 1 2 0 -0.0006 9 0 0 0 5.27E+06 1.66E+06 - - - 3.3385 1 230117_WJC_METTL3_WT_vs_EV_F03.19492.19492.2 0.000127 15/26 R.LIVVLEGASLETVK.V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1469.8705 1.09 24502 19492 2 1469.871686 735.9425 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3690.5 - 482000 - - - 0.8096 - 3.076 0.553 - 716.9 1 2 0 0.0012 14 0 0 0 3.52E+06 3.22E+06 - - - 5.9448 0.9955 230117_WJC_METTL3_WT_vs_EV_F03.19497.19497.2 0.0266 18-Sep R.EALLAALGYK[136.11].N sp|Q9BU76|MMTA2_HUMAN 1 1055.6106 0.73 24505 19497 2 1055.616068 528.8126 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3691.2 - 1.14E+06 - - - 5.1354 - 2.089 0.259 - 232.7 1 2 0 0.0054 10 0 0 0 1.99E+07 2.72E+07 - - - 3.0086 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.19498.19498.2 0.0146 18-Aug R.EALLAALGYK.N sp|Q9BU76|MMTA2_HUMAN 1 1047.5964 0.73 24506 19498 2 1047.60115 524.8055 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3691.3 - 797221 - - - 4.4893 - 2.093 0.344 - 131.9 1 2 0 0.0047 10 0 0 0 1.99E+07 2.72E+07 - - - 3.642 0.9687 230117_WJC_METTL3_WT_vs_EV_F03.19500.19500.3 1.29 Jul-40 R.LLESLDQLELR.V sp|O95816|BAG2_HUMAN 1 1327.7347 12.1 24508 19500 3 1327.738938 443.5855 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.14 3691.6 - 616734 - - - 3.1686 - 1.462 0.152 - 60.7 2 2 0 0.0042 11 0 0 0 2.85E+06 2.36E+05 - - - 1.1731 0.9935 230117_WJC_METTL3_WT_vs_EV_F03.19506.19506.2 0.00108 20-Aug K.VAPGFQFFATR.R sp|Q9NU22|MDN1_HUMAN 1 1239.64 0.98 24514 19506 2 1239.647394 620.8273 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 9.72 3692.3 - 333209 - - - 5.9299 - 1.72 0.369 - 150.5 1 2 0 0.0074 11 0 0 0 4.52E+06 4.61E+06 - - - 3.2312 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.19507.19507.2 0.000841 22-Sep R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.25 24515 19507 2 1315.790896 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3692.5 - 301421 - - - 3.4375 - 1.707 0.248 - 216.4 1 2 0 0.0045 12 0 0 0 3.18E+06 2.55E+06 - - - 2.2783 0.9746 230117_WJC_METTL3_WT_vs_EV_F03.19508.19508.2 1.69 12-Jun R.AFLPLLK.A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 800.516 1.3 24516 19508 2 800.51852 401.2653 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3692.6 - 273028 - - - 3.1342 - 1.234 0.08 - 172.7 1 2 0 0.0025 7 0 0 0 1.33E+07 1.02E+07 - - - 0.2973 0.8459 230117_WJC_METTL3_WT_vs_EV_F03.19510.19510.2 0.122 14-Jul K.INFDALLK[136.11].F "sp|P55061|BI1_HUMAN,tr|F8VX73|F8VX73_HUMAN,tr|F8W201|F8W201_HUMAN,tr|F8VSI7|F8VSI7_HUMAN,tr|F8VVJ4|F8VVJ4_HUMAN,tr|F8VPI1|F8VPI1_HUMAN,tr|F8W086|F8W086_HUMAN,tr|F8VQQ5|F8VQQ5_HUMAN,tr|F8VQW0|F8VQW0_HUMAN,tr|F8VR05|F8VR05_HUMAN,tr|F8W1G3|F8W1G3_HUMAN" 11 940.5473 1.38 24518 19510 2 940.551871 471.2809 Bax inhibitor 1 OS=Homo sapiens OX=9606 GN=TMBIM6 PE=1 SV=2 5.84 3692.9 - 266000 - - - 4.8408 - 1.255 0.007 - 75.7 1 2 0 0.0046 8 0 0 0 2.19E+06 1.59E+06 - - - -0.2237 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19512.19512.2 0.000341 20-Dec R.ILSDTTLWLC[160.03]R.L "sp|Q6P996|PDXD1_HUMAN,sp|Q6P474|PDXD2_HUMAN,tr|J3KNK7|J3KNK7_HUMAN,tr|H3BQ54|H3BQ54_HUMAN,tr|H3BNL6|H3BNL6_HUMAN,tr|Q86XE2|Q86XE2_HUMAN,tr|H3BU11|H3BU11_HUMAN,tr|H3BND4|H3BND4_HUMAN" 8 1376.7122 0.94 24520 19512 2 1376.717389 689.3634 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 5.83 3693.1 - 234576 - - - 3.7531 - 2.148 0.409 - 550.7 1 2 0 0.0052 11 0 0 0 1.98E+06 2.10E+06 - - - 4.1285 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19519.19519.2 0.00511 18-Sep K.IELFADVVPK.T "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 1129.6383 1.81 24526 19519 2 1129.639951 565.8264 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.37 3693.9 - 1.41E+06 - - - 1.4518 - 2.114 0.318 - 235.1 1 2 0 0.0016 10 0 0 0 7.27E+07 4.01E+07 - - - 3.4788 1 230117_WJC_METTL3_WT_vs_EV_F03.19520.19520.2 0.000594 20-Nov R.LLESLDQLELR[166.11].V sp|O95816|BAG2_HUMAN 1 1337.743 8.98 24527 19520 2 1337.742404 669.8788 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.14 3694 - 208852 - - - -0.4463 - 2.358 0.446 - 367.1 1 2 0 -0.0006 11 0 0 0 2.04E+08 2.27E+07 - - - 4.6556 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.19535.19535.2 0.00189 20-Dec R.LALVISELEGK[136.11].A "sp|Q12899|TRI26_HUMAN,tr|A2AE48|A2AE48_HUMAN" 2 1178.7002 1.27 24540 19535 2 1178.705392 590.3574 Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1 4.53 3695.8 - 362986 - - - 4.4133 - 2.622 0.283 - 431.7 1 2 0 0.0052 11 0 0 0 4.59E+06 3.60E+06 - - - 3.7373 0.9969 230117_WJC_METTL3_WT_vs_EV_F03.19536.19536.2 0.113 14-Jun K.VLIVVPFR.E "sp|Q68CQ4|UTP25_HUMAN,tr|H7C2R4|H7C2R4_HUMAN" 2 941.6062 1.53 24541 19536 2 941.607722 471.8104 U3 small nucleolar RNA-associated protein 25 homolog OS=Homo sapiens OX=9606 GN=UTP25 PE=1 SV=2 9.72 3695.9 - 360965 - - - 1.592 - 1.393 0.177 - 81.8 1 2 0 0.0015 8 0 0 0 1.84E+06 1.21E+06 - - - 1.3475 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.19539.19539.2 0.0186 14-Aug R.YELALILK[136.11].A sp|P82932|RT06_HUMAN 1 969.599 2.47 24544 19539 2 969.598076 485.8068 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3696.3 - 256281 - - - -0.9726 - 1.633 0.337 - 157.3 1 2 0 -0.0009 8 0 0 0 1.17E+07 4.73E+06 - - - 3.0089 0.9876 230117_WJC_METTL3_WT_vs_EV_F03.19547.19547.2 1.3 12-Jun R.AFLPLLK[136.11].A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 808.5302 1.3 24551 19547 2 808.531273 405.2724 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3697.1 - 1.54E+06 - - - 1.3135 - 1.246 0.079 - 189.3 1 2 0 0.0011 7 0 0 0 1.33E+07 1.02E+07 - - - 0.321 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19548.19548.2 0.000314 14-Sep R.YELALILK.A sp|P82932|RT06_HUMAN 1 961.5848 2.47 24552 19548 2 961.586906 481.7997 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3697.1 - 1.34E+06 - - - 2.1704 - 1.739 0.41 - 226 1 2 0 0.0021 8 0 0 0 1.17E+07 4.73E+06 - - - 3.7374 0.9736 230117_WJC_METTL3_WT_vs_EV_F03.19550.19550.2 0.056 20-Oct K.VAPGFQFFATR[166.11].R sp|Q9NU22|MDN1_HUMAN 1 1249.6483 1.31 24554 19550 2 1249.65537 625.8314 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 9.72 3697.4 - 462685 - - - 5.6472 - 1.637 0.157 - 274.4 1 2 0 0.0071 11 0 0 0 4.39E+06 3.36E+06 - - - 1.5317 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19554.19554.2 0.000102 18-Jul K.LFGYEMAEFK[136.11].V sp|Q9UKD2|MRT4_HUMAN 1 1241.5882 0.86 24558 19554 2 1241.58932 621.8014 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 4.53 3697.9 - 381849 - - - 0.9045 - 1.524 0.505 - 104.7 1 2 0 0.0011 10 0 0 0 3.03E+06 3.51E+06 - - - 3.9467 0.9886 230117_WJC_METTL3_WT_vs_EV_F03.19563.19563.2 0.000507 18-Dec R.IINDLLQSLR.S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1183.6925 2.12 24565 19563 2 1183.699545 592.8535 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3698.9 - 1.02E+07 - - - 5.9754 - 2.309 0.161 - 465.6 1 2 0 0.0071 10 0 0 0 1.29E+08 6.10E+07 - - - 2.5637 0.9943 230117_WJC_METTL3_WT_vs_EV_F03.19564.19564.2 1.04 18-Nov R.IINDLLQSLR[166.11].S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1193.7007 2.11 24566 19564 2 1193.706645 597.8576 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3699 - 5.35E+06 - - - 4.9451 - 2.252 0.169 - 304.5 1 2 0 0.0059 10 0 0 0 1.28E+08 6.08E+07 - - - 2.5534 1 230117_WJC_METTL3_WT_vs_EV_F03.19566.19566.2 5.40E-05 22-Dec R.IEGVLLLGEPVR.W "sp|Q9BXW7|HDHD5_HUMAN,tr|A8MYZ9|A8MYZ9_HUMAN" 2 1293.7656 2.94 24568 19566 2 1293.76968 647.8901 Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Homo sapiens OX=9606 GN=HDHD5 PE=1 SV=1 4.53 3699.2 - 802417 - - - 3.125 - 2.831 0.469 - 740.7 1 2 0 0.004 12 0 0 0 3.78E+06 1.28E+06 - - - 5.2418 1 230117_WJC_METTL3_WT_vs_EV_F03.19567.19567.2 7.92E-07 22-Nov K.VLLSPDYLPAMR.R sp|Q7Z6Z7|HUWE1_HUMAN 1 1373.7377 2.09 24569 19567 2 1373.744846 687.8761 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.81 3699.3 - 740971 - - - 5.196 - 2.292 0.556 - 424 1 2 0 0.0071 12 0 0 0 4.36E+06 2.09E+06 - - - 5.3277 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19569.19569.2 0.000189 18-Nov K.LFGYEMAEFK.V sp|Q9UKD2|MRT4_HUMAN 1 1233.574 0.86 24571 19569 2 1233.577768 617.7943 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 4.53 3699.6 - 615300 - - - 3.057 - 1.716 0.518 - 268.8 1 2 0 0.0038 10 0 0 0 3.03E+06 3.51E+06 - - - 4.3731 0.9255 230117_WJC_METTL3_WT_vs_EV_F03.19572.19572.2 0.569 14-Jun K.DFAIDIIK.S sp|Q15181|IPYR_HUMAN 1 933.5171 2.77 24574 19572 2 933.52198 467.7658 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 4.21 3700 - 273822 - - - 5.1911 - 1.173 0.129 - 74 1 2 0 0.0048 8 0 0 0 1.62E+06 5.87E+05 - - - 0.4735 0.9852 230117_WJC_METTL3_WT_vs_EV_F03.19575.19575.2 0.133 22-Aug R.FSELANDPILWK.R "sp|Q86XK2|FBX11_HUMAN,tr|C9IYF0|C9IYF0_HUMAN,tr|A0A804HK63|A0A804HK63_HUMAN" 3 1431.7398 -1 24577 19575 2 1431.746264 716.8772 F-box only protein 11 OS=Homo sapiens OX=9606 GN=FBXO11 PE=1 SV=3 4.37 3700.4 - 138490 - - - 4.5029 - 1.529 0.165 - 130.3 1 2 0 0.0064 12 0 0 0 0.00E+00 0.00E+00 - - - 1.3749 1 230117_WJC_METTL3_WT_vs_EV_F03.19582.19582.2 0.00111 18-Nov R.LGLEDFESLK[136.11].V sp|Q15208|STK38_HUMAN 1 1157.606 0.59 24583 19582 2 1157.610982 579.8103 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3701.1 - 8.02E+06 - - - 4.3426 - 2.415 0.488 - 315.9 1 2 0 0.005 10 0 0 0 1.50E+08 2.53E+08 - - - 5.1049 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19583.19583.2 0.0073 18-Oct R.LGLEDFESLK.V sp|Q15208|STK38_HUMAN 1 1149.5918 0.6 24584 19583 2 1149.596408 575.8032 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3701.1 - 3.63E+06 - - - 4.0475 - 2.236 0.444 - 222.9 1 2 0 0.0047 10 0 0 0 1.51E+08 2.54E+08 - - - 4.5651 0.999 230117_WJC_METTL3_WT_vs_EV_F03.19586.19586.2 0.000761 20-Nov K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 3.45 24587 19586 2 1276.70767 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3701.4 - 1.27E+06 - - - 3.8905 - 2.521 0.328 - 545.1 1 2 0 0.005 11 0 0 0 3.84E+06 1.11E+06 - - - 3.9635 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19587.19587.2 0.00244 18-Nov R.TALYNYIFAK.K "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1202.6336 3.25 24588 19587 2 1202.635002 602.3241 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 8.17 3701.5 - 1.22E+06 - - - 1.199 - 2.1 0.368 - 359.6 1 2 0 0.0014 10 0 0 0 3.80E+06 1.17E+06 - - - 3.8296 1 230117_WJC_METTL3_WT_vs_EV_F03.19590.19590.2 7.97E-09 26-Dec K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 3.49 24591 19590 2 1762.80068 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3701.9 - 638254 - - - 3.1654 - 2.277 0.673 - 444.9 1 2 0 0.0056 14 0 0 0 2.40E+06 6.87E+05 - - - 6.0749 1 230117_WJC_METTL3_WT_vs_EV_F03.19591.19591.2 0.0084 13/22 Y.AIYELAVASFPK.K "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6R9C3|D6R9C3_HUMAN" 4 1307.7125 1.53 24592 19591 2 1307.717685 654.8635 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 6.05 3702 - 572049 - - - 3.9351 - 2.701 0.435 - 655.6 1 1 0 0.0051 12 0 0 0 2.51E+06 1.64E+06 - - - 4.8667 0.978 230117_WJC_METTL3_WT_vs_EV_F03.19595.19595.2 0.387 20-Aug K.LALDIEIATYR[166.11].K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1286.711 -1 24596 19595 2 1286.717957 644.3628 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3702.5 - 418247 - - - 5.4278 - 1.731 0.141 - 181.5 1 2 0 0.007 11 0 0 0 0.00E+00 0.00E+00 - - - 1.5646 1 230117_WJC_METTL3_WT_vs_EV_F03.19596.19596.2 1.03E-07 13/26 K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 3.49 24597 19596 2 1772.803861 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3702.7 - 256253 - - - 0.277 - 2.425 0.658 - 627.3 1 2 0 0.0005 14 0 0 0 2.40E+06 6.87E+05 - - - 6.1238 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.19603.19603.2 0.00655 16-Sep K.ALEVYDLIR.T "sp|Q9H5X1|CIA2A_HUMAN,tr|H0YKV4|H0YKV4_HUMAN" 2 1090.6023 1.43 24603 19603 2 1090.607594 546.3084 Cytosolic iron-sulfur assembly component 2A OS=Homo sapiens OX=9606 GN=CIAO2A PE=1 SV=1 4.37 3703.5 - 2.39E+06 - - - 4.8909 - 1.966 0.385 - 389.4 1 2 0 0.0053 9 0 0 0 8.42E+06 5.91E+06 - - - 3.8386 0.9965 230117_WJC_METTL3_WT_vs_EV_F03.19604.19604.2 0.865 16-Aug K.ALEVYDLIR[166.11].T "sp|Q9H5X1|CIA2A_HUMAN,tr|H0YKV4|H0YKV4_HUMAN" 2 1100.6105 1.49 24604 19604 2 1100.614352 551.3125 Cytosolic iron-sulfur assembly component 2A OS=Homo sapiens OX=9606 GN=CIAO2A PE=1 SV=1 4.37 3703.6 - 1.73E+06 - - - 3.4726 - 1.731 0.19 - 303.1 1 2 0 0.0038 9 0 0 0 8.12E+06 5.44E+06 - - - 2.0306 0.9926 230117_WJC_METTL3_WT_vs_EV_F03.19605.19605.2 0.0917 16-Aug K.LQLSLADFR[166.11].R "sp|O00541|PESC_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 2 1071.5952 1.13 24605 19605 2 1071.600846 536.8049 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 5.84 3703.7 - 1.54E+06 - - - 5.2548 - 1.656 0.272 - 183.8 1 2 0 0.0056 9 0 0 0 1.67E+07 1.48E+07 - - - 2.5075 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.19606.19606.2 0.0188 14-Sep K.VAIIIPFR[166.11].N "sp|P15291|B4GT1_HUMAN,sp|O43286|B4GT5_HUMAN,tr|Q86XA6|Q86XA6_HUMAN" 3 937.5988 -1 24606 19606 2 937.601699 469.8067 "Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5" 9.72 3703.9 - 894205 - - - 3.0461 - 1.947 0.228 - 312 1 2 0 0.0029 8 0 0 0 0.00E+00 0.00E+00 - - - 2.7336 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.19608.19608.2 0.386 14-Oct K.VAIIIPFR.N "sp|P15291|B4GT1_HUMAN,sp|O43286|B4GT5_HUMAN,tr|Q86XA6|Q86XA6_HUMAN" 3 927.5906 0.18 24608 19608 2 927.593456 464.8026 "Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5" 9.72 3704.1 - 704268 - - - 3.1081 - 2.005 0.215 - 385.7 1 2 0 0.0029 8 0 0 0 4.68E+06 2.56E+07 - - - 2.7261 0.9847 230117_WJC_METTL3_WT_vs_EV_F03.19609.19609.2 0.0935 18-Oct R.TEVVSLLLDR.K "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1143.6499 1.91 24609 19609 2 1143.6581 572.8322 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 3704.2 - 639430 - - - 7.1359 - 1.877 0.31 - 260.7 1 2 0 0.0082 10 0 0 0 1.64E+07 8.56E+06 - - - 3.0857 0.9819 230117_WJC_METTL3_WT_vs_EV_F03.19610.19610.2 0.0797 12-Jun R.EAYFWLR.Q sp|Q8TCJ2|STT3B_HUMAN 1 983.4865 1.18 24610 19610 2 983.490509 492.7505 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1 6.1 3704.4 - 579305 - - - 4.0743 - 1.1 0.222 - 146.2 1 2 0 0.004 7 0 0 0 2.84E+06 2.41E+06 - - - 0.9814 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19612.19612.2 0.0986 24-Dec R.LENLGIPEEELLR.Q sp|Q01658|NC2B_HUMAN 1 1523.8195 -1 24612 19612 2 1523.819956 762.917 Protein Dr1 OS=Homo sapiens OX=9606 GN=DR1 PE=1 SV=1 4.09 3704.6 - 411526 - - - 0.2842 - 2.738 0.387 - 393.2 1 2 0 0.0004 13 0 0 0 0.00E+00 0.00E+00 - - - 4.4843 0.9952 230117_WJC_METTL3_WT_vs_EV_F03.19614.19614.2 0.0126 22-Aug R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 0.95 24614 19614 2 1323.805505 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3704.9 - 338051 - - - 3.7256 - 1.346 0.28 - 131.7 1 2 0 0.0049 12 0 0 0 1.98E+06 2.07E+06 - - - 1.8893 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.19615.19615.2 0.0488 12-May R.EAYFWLR[166.11].Q sp|Q8TCJ2|STT3B_HUMAN 1 993.4948 1.39 24615 19615 2 993.49744 497.7547 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1 6.1 3705 - 329410 - - - 2.6855 - 1.349 0.32 - 80.5 1 2 0 0.0027 7 0 0 0 2.77E+06 2.00E+06 - - - 2.3522 1 230117_WJC_METTL3_WT_vs_EV_F03.19617.19617.2 1.51E-05 16/32 R.IQEIIEQLDVTTSEYEK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2037.0154 -1 24617 19617 2 2037.022677 1019.515 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3705.3 - 274194 - - - 3.5812 - 3.781 0.596 - 588.8 1 2 0 0.0073 17 0 0 0 0.00E+00 0.00E+00 - - - 6.7106 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19618.19618.2 0.00125 24-Nov R.LENLGIPEEELLR[166.11].Q sp|Q01658|NC2B_HUMAN 1 1533.8278 2.51 24618 19618 2 1533.831674 767.9212 Protein Dr1 OS=Homo sapiens OX=9606 GN=DR1 PE=1 SV=1 4.09 3705.4 - 249971 - - - 2.5303 - 2.39 0.431 - 258.2 1 2 0 0.0039 13 0 0 0 2.47E+06 9.83E+05 - - - 4.4593 0.9101 230117_WJC_METTL3_WT_vs_EV_F03.19623.19623.2 0.198 14-Sep L.IALALLAR.R sp|P43116|PE2R2_HUMAN 1 839.5593 999 24622 19623 2 839.560453 420.7869 Prostaglandin E2 receptor EP2 subtype OS=Homo sapiens OX=9606 GN=PTGER2 PE=1 SV=2 9.75 3706.1 - 201390 - - - 1.4055 - 1.889 0.163 - 352.7 1 1 0 0.0012 8 0 0 0 7.09E+06 0.00E+00 - - - 2.1628 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.19624.19624.2 0.00255 18-Sep K.VAEITELILK.A "sp|Q06265|EXOS9_HUMAN,tr|D6R905|D6R905_HUMAN,tr|H0Y9L5|H0Y9L5_HUMAN,tr|D6RIY6|D6RIY6_HUMAN" 4 1127.6802 1.24 24623 19624 2 1127.686244 564.8474 Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3 4.53 3706.2 - 1.92E+06 - - - 5.381 - 2.135 0.344 - 284.9 1 2 0 0.0061 10 0 0 0 1.74E+07 1.40E+07 - - - 3.697 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.19625.19625.2 0.000124 18-Oct K.VAEITELILK[136.11].A "sp|Q06265|EXOS9_HUMAN,tr|D6R905|D6R905_HUMAN,tr|H0Y9L5|H0Y9L5_HUMAN,tr|D6RIY6|D6RIY6_HUMAN" 4 1135.6944 1.24 24624 19625 2 1135.700825 568.8545 Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3 4.53 3706.3 - 1.73E+06 - - - 5.6785 - 2.251 0.389 - 396.3 1 2 0 0.0064 10 0 0 0 1.74E+07 1.40E+07 - - - 4.1769 0.997 230117_WJC_METTL3_WT_vs_EV_F03.19627.19627.2 0.00584 16-Nov K.LQLSLADFR.R "sp|O00541|PESC_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 2 1061.5869 1.13 24626 19627 2 1061.592819 531.8007 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 5.84 3706.6 - 1.34E+06 - - - 5.5332 - 2.101 0.401 - 428.9 1 2 0 0.0059 9 0 0 0 1.67E+07 1.48E+07 - - - 4.1488 0.9866 230117_WJC_METTL3_WT_vs_EV_F03.19631.19631.2 0.125 14-May R.LLFFAPTR.R sp|Q07820|MCL1_HUMAN 1 963.5542 3.65 24630 19631 2 963.558132 482.7844 Induced myeloid leukemia cell differentiation protein Mcl-1 OS=Homo sapiens OX=9606 GN=MCL1 PE=1 SV=3 9.75 3707.1 - 389761 - - - 4.0932 - 1.368 0.168 - 92.1 1 2 0 0.0039 8 0 0 0 3.32E+06 9.10E+05 - - - 1.2257 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.19634.19634.2 1.18 12-Jul K.LTFLDLR.N "sp|Q9H9A6|LRC40_HUMAN,tr|X6R5P2|X6R5P2_HUMAN" 2 876.5069 2.02 24633 19634 2 876.509345 439.2607 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.84 3707.5 - 303962 - - - 2.7861 - 1.501 0.144 - 216.4 1 2 0 0.0024 7 0 0 0 6.28E+06 3.11E+06 - - - 1.3907 0.9701 230117_WJC_METTL3_WT_vs_EV_F03.19635.19635.3 0.0448 Oct-64 R.IQEIIEQLDVTTSEYEK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2037.0154 -1 24634 19635 3 2037.026723 680.0124 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3707.6 - 266250 - - - 5.5675 - 1.532 0.24 - 84.7 1 2 0 0.0113 17 0 0 0 0.00E+00 0.00E+00 - - - 2.2903 0.9461 230117_WJC_METTL3_WT_vs_EV_F03.19636.19636.2 0.208 12-Jun K.LTFLDLR[166.11].N "sp|Q9H9A6|LRC40_HUMAN,tr|X6R5P2|X6R5P2_HUMAN" 2 886.5152 1.99 24635 19636 2 886.519112 444.2649 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.84 3707.7 - 252399 - - - 4.4432 - 1.353 0.067 - 131.5 2 2 0 0.0039 7 0 0 0 6.18E+06 3.11E+06 - - - 0.3581 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19638.19638.3 2.01E-05 13/40 R.MLIPYIEHWPR.A "sp|O75208|COQ9_HUMAN,tr|H3BPY0|H3BPY0_HUMAN,tr|H3BNT2|H3BNT2_HUMAN" 3 1453.754 5.92 24637 19638 3 1453.761507 485.592 "Ubiquinone biosynthesis protein COQ9, mitochondrial OS=Homo sapiens OX=9606 GN=COQ9 PE=1 SV=1" 6.5 3708 - 204226 - - - 5.1453 - 2.622 0.46 - 323.5 1 2 0 0.0075 11 0 0 0 4.02E+06 6.79E+05 - - - 6.4049 0.8803 230117_WJC_METTL3_WT_vs_EV_F03.19643.19643.2 1.34 14-May R.GLDIYVWR.G sp|Q13045|FLII_HUMAN 1 1020.5393 1.37 24641 19643 2 1020.543014 511.2769 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3708.6 - 214260 - - - 3.6726 - 0.951 0.077 - 51.7 1 2 0 0.0037 8 0 0 0 4.11E+06 3.01E+06 - - - -0.543 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19645.19645.2 0.00979 12-Aug K.NFGIWLR[166.11].Y "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 914.5002 0.77 24643 19645 2 914.501799 458.2574 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 9.75 3708.8 - 1.18E+06 - - - 1.7572 - 1.669 0.259 - 390 1 2 0 0.0016 7 0 0 0 1.06E+08 1.38E+08 - - - 2.5765 1 230117_WJC_METTL3_WT_vs_EV_F03.19648.19648.2 2.80E-07 26-Oct R.IMGIPEEEQMGLLR[166.11].V sp|P35579|MYH9_HUMAN 1 1624.8192 1.19 24646 19648 2 1624.828413 813.4169 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3709 - 390695 - - - 5.6585 - 1.936 0.571 - 231.2 1 2 0 0.0092 14 0 0 0 8.98E+06 7.56E+06 - - - 4.9133 1 230117_WJC_METTL3_WT_vs_EV_F03.19649.19649.2 2.38E-05 13/22 R.LPADTC[160.03]LLEFAR.L "sp|Q8NF37|PCAT1_HUMAN,tr|A0A0G2JQ62|A0A0G2JQ62_HUMAN,tr|A0A0G2JRI7|A0A0G2JRI7_HUMAN" 3 1404.7071 1.46 24647 19649 2 1404.713421 703.3608 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 4.37 3709.1 - 322429 - - - 4.4742 - 2.454 0.529 - 792.8 1 2 0 0.0063 12 0 0 0 6.24E+06 4.26E+06 - - - 5.3083 1 230117_WJC_METTL3_WT_vs_EV_F03.19653.19653.2 1.82E-06 24-Dec R.LGIGMDTC[160.03]VIPLR.H "sp|P49903|SPS1_HUMAN,tr|Q5T5U6|Q5T5U6_HUMAN" 2 1443.7578 42.85 24651 19653 2 1443.764198 722.8862 "Selenide, water dikinase 1 OS=Homo sapiens OX=9606 GN=SEPHS1 PE=1 SV=2" 5.83 3709.4 - 0 - - - 4.437 - 2.446 0.544 - 483.2 1 2 0 0.0064 13 0 0 0 1.79E+06 4.19E+04 - - - 5.3526 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19660.19660.2 0.00972 20-Oct R.LFEAEAQDLFR.D sp|Q9H223|EHD4_HUMAN 1 1337.6616 2.15 24656 19660 2 1337.663865 669.8381 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3710.3 - 1.49E+06 - - - 1.7187 - 2.293 0.426 - 331.6 1 2 0 0.0023 11 0 0 0 3.32E+07 1.54E+07 - - - 4.4317 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.19661.19661.2 0.0153 14-Aug K.DFLIPIGK[136.11].A "sp|P11177|ODPB_HUMAN,tr|F8WF02|F8WF02_HUMAN,tr|C9J634|C9J634_HUMAN" 3 909.5415 1.74 24657 19661 2 909.543748 455.778 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 5.84 3710.4 - 1.14E+06 - - - 2.4672 - 1.66 0.15 - 275 1 2 0 0.0022 8 0 0 0 3.95E+07 2.27E+07 - - - 1.6767 1 230117_WJC_METTL3_WT_vs_EV_F03.19664.19664.2 5.39E-10 16/24 K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 0.54 24660 19664 2 1600.747608 801.3794 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3710.8 - 1.24E+06 - - - 2.0603 - 2.648 0.631 - 798 1 2 0 0.0033 13 0 0 0 1.04E+07 1.92E+07 - - - 6.1998 1 230117_WJC_METTL3_WT_vs_EV_F03.19665.19665.2 2.40E-07 15/28 R.VMAGALEGDIFIGPK.A "sp|P61163|ACTZ_HUMAN,sp|P42025|ACTY_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 4 1516.796 1.53 24661 19665 2 1516.79954 759.4053 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4.37 3710.9 - 931470 - - - 2.3662 - 2.686 0.613 - 658.8 1 2 0 0.0036 15 0 0 0 1.93E+07 1.26E+07 - - - 5.9967 0.996 230117_WJC_METTL3_WT_vs_EV_F03.19666.19666.2 1.33 14-Jul K.LLILALER[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 949.62 1.29 24662 19666 2 949.622644 475.8173 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6 3711.1 - 929327 - - - 2.8127 - 1.433 0.191 - 157.2 1 2 0 0.0027 8 0 0 0 3.64E+07 2.82E+07 - - - 1.5359 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.19667.19667.2 0.0156 14-Sep R.NLFEQLVR.R "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VV47|F8VV47_HUMAN,tr|F8VUW9|F8VUW9_HUMAN,tr|F8VWY4|F8VWY4_HUMAN,tr|F8VRD2|F8VRD2_HUMAN,tr|F8VVY0|F8VVY0_HUMAN,tr|F8VZ66|F8VZ66_HUMAN,tr|F8VWX0|F8VWX0_HUMAN,tr|F8VS54|F8VS54_HUMAN,tr|F8W0L1|F8W0L1_HUMAN,tr|F8VVE5|F8VVE5_HUMAN,tr|F8VV39|F8VV39_HUMAN,tr|F8VXH1|F8VXH1_HUMAN" 13 1017.5607 3.01 24663 19667 2 1017.563061 509.7876 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 6 3711.2 - 919739 - - - 2.2908 - 1.518 0.244 - 262.2 1 2 0 0.0023 8 0 0 0 1.33E+07 4.42E+06 - - - 2.1013 0.9888 230117_WJC_METTL3_WT_vs_EV_F03.19668.19668.2 0.0393 16-Jul K.STLINTLFK.S "sp|Q9UHD8|SEPT9_HUMAN,tr|K7EKN4|K7EKN4_HUMAN,tr|K7EN52|K7EN52_HUMAN,tr|K7EQD7|K7EQD7_HUMAN,tr|K7ER52|K7ER52_HUMAN,tr|A0A6Q8PHC2|A0A6Q8PHC2_HUMAN,tr|K7ER14|K7ER14_HUMAN,tr|K7EIE4|K7EIE4_HUMAN,tr|K7EJZ2|K7EJZ2_HUMAN,tr|K7ENQ5|K7ENQ5_HUMAN,tr|K7EL40|K7EL40_HUMAN,tr|K7EK18|K7EK18_HUMAN" 12 1035.5964 1.32 24664 19668 2 1035.600043 518.8055 Septin-9 OS=Homo sapiens OX=9606 GN=SEPTIN9 PE=1 SV=2 8.47 3711.3 - 863026 - - - 3.4724 - 1.198 0.2 - 100.9 1 2 0 0.0036 9 0 0 0 4.84E+06 3.67E+06 - - - 1.0397 1 230117_WJC_METTL3_WT_vs_EV_F03.19669.19669.2 3.82E-08 13/26 R.IMGIPEEEQMGLLR.V sp|P35579|MYH9_HUMAN 1 1614.8109 1.19 24665 19669 2 1614.815918 808.4128 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3711.4 - 851257 - - - 3.0771 - 2.408 0.614 - 409.4 1 2 0 0.005 14 0 0 0 8.98E+06 7.56E+06 - - - 5.7797 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.19670.19670.2 1.04 14-Aug K.SLLAGLLK[136.11].K "sp|P31751|AKT2_HUMAN,tr|M0R0P9|M0R0P9_HUMAN,tr|J3QKW1|J3QKW1_HUMAN,tr|J3QL45|J3QL45_HUMAN,tr|M0R283|M0R283_HUMAN,tr|M0QZW8|M0QZW8_HUMAN" 6 821.5466 0.86 24666 19670 2 821.548453 411.7806 RAC-beta serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=AKT2 PE=1 SV=2 8.47 3711.6 - 819006 - - - 2.2677 - 1.542 0.229 - 199.3 1 2 0 0.0019 8 0 0 0 4.56E+06 5.32E+06 - - - 2.038 1 230117_WJC_METTL3_WT_vs_EV_F03.19671.19671.2 1.39E-07 15/24 K.IYVDDGLISLQVK[136.11].Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1469.8221 1.4 24667 19671 2 1469.825144 735.9183 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3711.7 - 779223 - - - 2.0737 - 2.618 0.602 - 547.2 1 2 0 0.003 13 0 0 0 1.68E+07 1.20E+07 - - - 5.9565 1 230117_WJC_METTL3_WT_vs_EV_F03.19672.19672.2 0.00963 20-Oct R.LFEAEAQDLFR[166.11].D sp|Q9H223|EHD4_HUMAN 1 1347.6698 2.15 24668 19672 2 1347.669372 674.8422 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3711.8 - 767182 - - - -0.3443 - 2.338 0.512 - 321.2 1 2 0 -0.0005 11 0 0 0 3.32E+07 1.54E+07 - - - 5.12 1 230117_WJC_METTL3_WT_vs_EV_F03.19673.19673.2 0.000472 13/22 R.LPADTC[160.03]LLEFAR[166.11].L "sp|Q8NF37|PCAT1_HUMAN,tr|A0A0G2JQ62|A0A0G2JQ62_HUMAN,tr|A0A0G2JRI7|A0A0G2JRI7_HUMAN" 3 1414.7154 1.46 24669 19673 2 1414.719952 708.365 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 4.37 3712 - 765371 - - - 3.2134 - 2.567 0.438 - 787.9 1 2 0 0.0045 12 0 0 0 6.24E+06 4.26E+06 - - - 4.7551 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.19676.19676.2 0.0343 14-Aug K.SVWALLQR[166.11].N sp|Q5VUD6|DIK1B_HUMAN 1 981.5635 0.94 24672 19676 2 981.56694 491.789 Divergent protein kinase domain 1B OS=Homo sapiens OX=9606 GN=DIPK1B PE=1 SV=3 9.47 3712.3 - 614687 - - - 3.4842 - 1.68 0.24 - 179.9 1 2 0 0.0034 8 0 0 0 2.46E+06 2.61E+06 - - - 2.3772 1 230117_WJC_METTL3_WT_vs_EV_F03.19677.19677.2 0.0153 24-Dec K.LLC[160.03]DSVVLQPYLR.E "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN,tr|H0YBB4|H0YBB4_HUMAN" 3 1574.8491 2.6 24673 19677 2 1574.854457 788.4318 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.83 3712.4 - 500928 - - - 3.4333 - 2.592 0.478 - 533.1 1 2 0 0.0054 13 0 0 0 7.36E+06 2.83E+06 - - - 5.0142 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.19679.19679.2 0.116 12-Jul K.NFGIWLR.Y "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 904.4919 0.77 24674 19679 2 904.494286 453.2532 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 9.75 3712.7 - 1.18E+07 - - - 2.6136 - 1.492 0.165 - 303.4 1 2 0 0.0024 7 0 0 0 1.06E+08 1.38E+08 - - - 1.5267 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19682.19682.2 7.90E-05 18-Nov K.LLDEVFFSEK.L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1225.6231 1.53 24677 19682 2 1225.623877 613.8188 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3712.9 - 1.51E+06 - - - 0.6707 - 2.29 0.423 - 318.3 1 2 0 0.0008 10 0 0 0 1.16E+08 7.60E+07 - - - 4.4778 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19683.19683.2 0.000281 18-Sep R.C[160.03]LFQSPLFAK.A sp|Q86X55|CARM1_HUMAN 1 1209.6216 2.15 24678 19683 2 1209.622109 605.8181 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 8.22 3712.9 - 1.19E+06 - - - 0.4076 - 1.585 0.538 - 218.8 1 2 0 0.0005 10 0 0 0 8.67E+06 4.03E+06 - - - 4.3001 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19684.19684.2 0.00316 24-Oct K.IYVDDGLISLQVK.Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1461.8079 1.4 24679 19684 2 1461.808572 731.9112 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3713 - 1.14E+06 - - - 0.4624 - 2.003 0.445 - 212.8 1 2 0 0.0007 13 0 0 0 1.68E+07 1.20E+07 - - - 4.1104 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.19686.19686.2 0.00151 16-Jul R.VLLPVLLNK.N sp|O00186|STXB3_HUMAN 1 1007.6743 1.85 24681 19686 2 1007.674832 504.8444 Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2 8.72 3713.1 - 647504 - - - 0.525 - 1.705 0.311 - 119.5 1 2 0 0.0005 9 0 0 0 8.64E+06 4.68E+06 - - - 2.8815 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19687.19687.2 0.00306 16-Aug K.VIPTLALLK[136.11].D sp|O14530|TXND9_HUMAN 1 974.662 1.83 24682 19687 2 974.664053 488.3383 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 8.72 3713.2 - 543550 - - - 2.1536 - 1.199 0.421 - 113.7 1 2 0 0.0021 9 0 0 0 1.07E+07 5.84E+06 - - - 2.6749 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.19688.19688.3 7.80E-06 16/68 K.ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1928.0719 10.93 24683 19688 3 1928.073005 643.6979 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3713.3 - 397224 - - - 0.5835 - 2.715 0.482 - 117.2 1 2 0 0.0011 18 0 0 0 1.11E+08 1.01E+07 - - - 6.4006 0.9958 230117_WJC_METTL3_WT_vs_EV_F03.19690.19690.2 0.0118 26-Jun K.LLLGSPSSLSPFSK.R "sp|Q9H165|BC11A_HUMAN,tr|A0A2U3TZJ5|A0A2U3TZJ5_HUMAN" 2 1431.7973 -1 24685 19690 2 1431.80221 716.9059 B-cell lymphoma\leukemia 11A OS=Homo sapiens OX=9606 GN=BCL11A PE=1 SV=2 8.75 3713.4 - 120316 - - - 3.4076 - 1.548 0.266 - 70.8 4 2 0 0.0049 14 0 0 0 0.00E+00 0.00E+00 - - - 1.8317 1 230117_WJC_METTL3_WT_vs_EV_F03.19694.19694.2 0.000378 18-Nov K.LLDEVFFSEK[136.11].L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1233.6373 1.53 24687 19694 2 1233.639465 617.8259 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3714 - 6.05E+06 - - - 1.7915 - 2.272 0.497 - 358.7 1 2 0 0.0022 10 0 0 0 1.16E+08 7.60E+07 - - - 5.0019 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.19695.19695.3 9.85E-05 Dec-68 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 2.4 24688 19695 3 1918.067741 640.3618 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3714 - 6.34E+06 - - - 2.1537 - 2.376 0.43 - 150.8 1 2 0 0.0041 18 0 0 0 2.27E+07 9.45E+06 - - - 5.4879 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.19697.19697.2 0.0166 16-Jul K.VIPTLALLK.D sp|O14530|TXND9_HUMAN 1 966.6478 1.83 24690 19697 2 966.649003 484.3312 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 8.72 3714.2 - 2.09E+06 - - - 1.2921 - 1.271 0.339 - 113.7 1 2 0 0.0012 9 0 0 0 1.07E+07 5.84E+06 - - - 2.2382 0.9156 230117_WJC_METTL3_WT_vs_EV_F03.19699.19699.2 6.14 14-May K.SLLAGLLK.K "sp|P31751|AKT2_HUMAN,tr|M0R0P9|M0R0P9_HUMAN,tr|J3QKW1|J3QKW1_HUMAN,tr|J3QL45|J3QL45_HUMAN,tr|M0R283|M0R283_HUMAN,tr|M0QZW8|M0QZW8_HUMAN" 6 813.5324 0.86 24692 19699 2 813.53304 407.7735 RAC-beta serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=AKT2 PE=1 SV=2 8.47 3714.4 - 1.33E+06 - - - 0.799 - 0.93 0.056 - 46.6 2 2 0 0.0006 8 0 0 0 4.56E+06 5.32E+06 - - - -0.8989 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.19701.19701.3 3.32E-05 13/76 R.LALVTGGEIASTFDHPELVK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2096.1154 999 24694 19701 3 2096.121119 699.7124 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 3714.6 - 834837 - - - 2.7422 - 2.59 0.482 - 153.9 1 2 0 0.0057 20 0 0 0 3.73E+06 0.00E+00 - - - 6.221 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19704.19704.2 5.53E-05 22-Oct K.ALSTFFVENSLR[166.11].T sp|Q9Y2V7|COG6_HUMAN 1 1392.7277 1.4 24697 19704 2 1392.729391 697.3711 Conserved oligomeric Golgi complex subunit 6 OS=Homo sapiens OX=9606 GN=COG6 PE=1 SV=2 6.05 3714.9 - 607773 - - - 1.2249 - 2.072 0.349 - 476.5 1 2 0 0.0017 12 0 0 0 4.53E+06 3.23E+06 - - - 3.535 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19705.19705.2 3.10E-05 24-Aug K.FIQVSYLESGIVR.G "sp|Q13459|MYO9B_HUMAN,tr|M0R300|M0R300_HUMAN,tr|M0R0P8|M0R0P8_HUMAN" 3 1509.8191 -1 24698 19705 2 1509.822136 755.9168 Unconventional myosin-IXb OS=Homo sapiens OX=9606 GN=MYO9B PE=1 SV=3 6 3715.1 - 573314 - - - 1.9916 - 1.943 0.442 - 178.1 1 2 0 0.003 13 0 0 0 0.00E+00 0.00E+00 - - - 4.0094 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19709.19709.2 2.62E-05 24-Sep K.LLC[160.03]DSVVLQPYLR[166.11].E "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN,tr|H0YBB4|H0YBB4_HUMAN" 3 1584.8573 2.6 24701 19709 2 1584.858842 793.4359 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.83 3715.5 - 137419 - - - 0.9603 - 1.876 0.469 - 218.8 1 2 0 0.0015 13 0 0 0 7.36E+06 2.83E+06 - - - 4.1193 1 230117_WJC_METTL3_WT_vs_EV_F03.19710.19710.2 3.63E-06 22-Oct K.ALSTFFVENSLR.T sp|Q9Y2V7|COG6_HUMAN 1 1382.7194 1.42 24702 19710 2 1382.716252 692.367 Conserved oligomeric Golgi complex subunit 6 OS=Homo sapiens OX=9606 GN=COG6 PE=1 SV=2 6.05 3715.6 - 228895 - - - -2.2875 - 2.2 0.497 - 308.2 1 2 0 -0.0032 12 0 0 0 4.71E+06 3.32E+06 - - - 4.7854 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19712.19712.2 0.00503 14-Sep K.IPDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1069.5584 1.26 24704 19712 2 1069.560091 535.7865 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3715.8 - 1.48E+06 - - - 1.5483 - 1.688 0.356 - 358.8 1 2 0 0.0017 8 0 0 0 4.45E+09 3.52E+09 - - - 3.2489 1 230117_WJC_METTL3_WT_vs_EV_F03.19714.19714.2 5.66E-05 13/22 R.IYGLGSLALYEK.A sp|P36542|ATPG_HUMAN 1 1325.7231 1.65 24706 19714 2 1325.728449 663.8688 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6 3716 - 752330 - - - 4.0318 - 2.583 0.462 - 439.7 1 2 0 0.0053 12 0 0 0 2.15E+08 1.30E+08 - - - 4.9485 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19715.19715.2 0.0403 16-Nov K.TLFPLIEAK[136.11].K sp|P13010|XRCC5_HUMAN 1 1038.6205 1.05 24707 19715 2 1038.622446 520.3175 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.66 3716.1 - 658689 - - - 1.89 - 1.705 0.352 - 325.1 1 2 0 0.002 9 0 0 0 2.51E+08 2.39E+08 - - - 3.1839 0.9521 230117_WJC_METTL3_WT_vs_EV_F03.19716.19716.2 0.00617 14-Aug F.GPILNFLR.H "sp|Q8N5Z5|KCD17_HUMAN,tr|H7C323|H7C323_HUMAN,tr|B0QYB2|B0QYB2_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 5 928.5494 0.56 24708 19716 2 928.549715 465.282 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 9.75 3716.3 - 504279 - - - 0.2994 - 1.905 0.304 - 318 1 1 0 0.0003 8 0 0 0 1.04E+07 1.86E+07 - - - 3.23 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19717.19717.2 0.00748 18-Oct R.C[160.03]LFQSPLFAK[136.11].A sp|Q86X55|CARM1_HUMAN 1 1217.6358 2.15 24709 19717 2 1217.636781 609.8252 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 8.22 3716.4 - 499425 - - - 0.7925 - 1.471 0.391 - 271.4 1 2 0 0.001 10 0 0 0 8.67E+06 4.03E+06 - - - 3.0059 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.19720.19720.2 0.201 14-Aug R.YILATLLK.E "sp|Q6PI48|SYDM_HUMAN,tr|A0A3B3IS01|A0A3B3IS01_HUMAN,tr|A0A3B3ISK7|A0A3B3ISK7_HUMAN,tr|A0A3B3IT01|A0A3B3IT01_HUMAN" 4 933.5899 1.61 24712 19720 2 933.591705 467.8022 "Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2 PE=1 SV=1" 8.59 3716.8 - 436515 - - - 1.928 - 1.322 0.197 - 169 1 2 0 0.0018 8 0 0 0 4.50E+06 2.80E+06 - - - 1.3374 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19721.19721.2 0.0171 20-Nov K.TAAFALPVLER.L "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 1186.671 1.03 24713 19721 2 1186.672923 594.3428 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.66 3716.9 - 418685 - - - 1.6129 - 2.155 0.409 - 446.3 1 2 0 0.0019 11 0 0 0 5.74E+06 5.59E+06 - - - 4.1383 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.19723.19723.2 0.0119 24-Oct R.GLLPGLLPAPADK[136.11].L sp|Q6P2E9|EDC4_HUMAN 1 1268.7584 1.58 24715 19723 2 1268.761868 635.3865 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 5.84 3717.2 - 300158 - - - 2.7539 - 1.962 0.34 - 283.3 1 2 0 0.0035 13 0 0 0 5.98E+06 3.79E+06 - - - 3.2809 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19728.19728.2 0.0162 16-Nov K.TLFPLIEAK.K sp|P13010|XRCC5_HUMAN 1 1030.6063 1.05 24719 19728 2 1030.609416 516.3104 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.66 3717.7 - 4.91E+06 - - - 3.04 - 1.696 0.376 - 331.7 1 2 0 0.0031 9 0 0 0 2.51E+08 2.39E+08 - - - 3.3455 1 230117_WJC_METTL3_WT_vs_EV_F03.19729.19729.2 0.00021 13/20 R.EVWALVQAGIR.D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1240.6928 1.33 24720 19729 2 1240.69552 621.3537 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.1 3717.8 - 2.18E+06 - - - 2.1867 - 2.348 0.454 - 681.1 1 2 0 0.0027 11 0 0 0 8.09E+06 6.08E+06 - - - 4.7025 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19730.19730.2 0.00263 18-Sep K.SVLIGEFLEK.V "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1133.6332 0.92 24721 19730 2 1133.635435 567.8239 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 3717.9 - 2.05E+06 - - - 1.9486 - 1.958 0.413 - 267.9 1 2 0 0.0022 10 0 0 0 7.19E+07 7.79E+07 - - - 3.9663 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19732.19732.2 0.00151 13/22 R.TFLESPLDVGIK.L "sp|Q8TEU7|RPGF6_HUMAN,tr|B7Z7Y1|B7Z7Y1_HUMAN,tr|E9PCH4|E9PCH4_HUMAN,tr|D6RE77|D6RE77_HUMAN,tr|A0A5F9ZHG7|A0A5F9ZHG7_HUMAN" 5 1317.718 0.17 24723 19732 2 1317.722173 659.8663 Rap guanine nucleotide exchange factor 6 OS=Homo sapiens OX=9606 GN=RAPGEF6 PE=1 SV=2 4.37 3718.1 - 1.01E+06 - - - 3.1532 - 2.29 0.443 - 475.4 1 2 0 0.0042 12 0 0 0 3.72E+07 2.18E+08 - - - 4.4918 0.999 230117_WJC_METTL3_WT_vs_EV_F03.19733.19733.2 0.017 16-Jul R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 -1 24724 19733 2 1006.573045 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3718.3 - 991318 - - - 3.1265 - 1.496 0.398 - 109.3 1 2 0 0.0031 9 0 0 0 0.00E+00 0.00E+00 - - - 3.1449 1 230117_WJC_METTL3_WT_vs_EV_F03.19736.19736.2 2.43E-06 15/24 A.TLSPTAVLILGPK.V "sp|Q8TDL5|BPIB1_HUMAN,tr|A2A2R0|A2A2R0_HUMAN" 2 1308.8017 999 24727 19736 2 1308.801405 655.4081 BPI fold-containing family B member 1 OS=Homo sapiens OX=9606 GN=BPIFB1 PE=1 SV=1 8.41 3718.7 - 476456 - - - -0.2162 - 2.671 0.562 - 685.7 1 1 0 -0.0003 13 0 0 0 3.10E+06 0.00E+00 - - - 5.7133 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19737.19737.2 0.00128 20-Sep R.EYIDYEFSVLK[136.11].E "sp|Q8IZH2|XRN1_HUMAN,tr|C9JCZ8|C9JCZ8_HUMAN" 2 1412.6955 1.24 24728 19737 2 1412.700123 707.355 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.14 3718.8 - 388361 - - - 3.2732 - 1.784 0.387 - 239.4 1 2 0 0.0046 11 0 0 0 1.61E+06 1.30E+06 - - - 3.4639 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.19738.19738.3 0.000296 Nov-36 K.LTLLTLHFPR.L "sp|Q92889|XPF_HUMAN,tr|A0A804HKF9|A0A804HKF9_HUMAN" 2 1209.7234 2.27 24729 19738 3 1209.728113 404.2484 DNA repair endonuclease XPF OS=Homo sapiens OX=9606 GN=ERCC4 PE=1 SV=3 9.76 3718.9 - 226679 - - - 3.9133 - 2.364 0.198 - 145.4 1 2 0 0.0047 10 0 0 0 1.74E+06 7.65E+05 - - - 3.2588 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19742.19742.2 0.00147 14-Sep K.IPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1059.5502 1.26 24732 19742 2 1059.553333 530.7824 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3719.4 - 5.60E+07 - - - 2.9899 - 1.797 0.498 - 466.8 1 2 0 0.0032 8 0 0 0 4.45E+09 3.52E+09 - - - 4.4859 0.9618 230117_WJC_METTL3_WT_vs_EV_F03.19744.19744.2 2.25 12-May K.FLPLFDR[166.11].V "sp|P61604|CH10_HUMAN,tr|S4R3N1|S4R3N1_HUMAN,tr|B8ZZL8|B8ZZL8_HUMAN" 3 916.5046 0.89 24733 19744 2 916.505475 459.2596 "10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2" 5.84 3719.6 - 4.86E+06 - - - 0.9449 - 1.038 0.078 - 99 2 2 0 0.0009 7 0 0 0 3.25E+07 3.65E+07 - - - -0.3995 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19745.19745.2 0.00196 18-Oct K.SVLIGEFLEK[136.11].V "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1141.6474 0.94 24734 19745 2 1141.648296 571.831 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 3719.7 - 9.30E+06 - - - 0.7621 - 1.963 0.445 - 344.4 1 2 0 0.0009 10 0 0 0 7.16E+07 7.59E+07 - - - 4.2102 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19746.19746.2 0.00168 18-Aug K.ELLGQGLLLR[166.11].S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1120.6844 0.92 24735 19746 2 1120.686248 561.3495 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3719.8 - 4.50E+06 - - - 1.6811 - 2.006 0.337 - 242.1 1 2 0 0.0019 10 0 0 0 1.36E+08 1.47E+08 - - - 3.4726 1 230117_WJC_METTL3_WT_vs_EV_F03.19747.19747.2 1.57E-06 14/22 K.ALEDAFLAIDAK.L sp|O15355|PPM1G_HUMAN 1 1275.6711 2.75 24736 19747 2 1275.672387 638.8428 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.03 3719.9 - 3.83E+06 - - - 1.034 - 2.702 0.516 - 533 1 2 0 0.0013 12 0 0 0 1.88E+07 6.86E+06 - - - 5.4671 0.9523 230117_WJC_METTL3_WT_vs_EV_F03.19748.19748.2 0.0184 14-Sep F.GPILNFLR[166.11].H "sp|Q8N5Z5|KCD17_HUMAN,tr|H7C323|H7C323_HUMAN,tr|B0QYB2|B0QYB2_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 5 938.5577 0.56 24737 19748 2 938.559173 470.2861 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 9.75 3720 - 3.23E+06 - - - 1.562 - 1.92 0.26 - 363.9 1 1 0 0.0015 8 0 0 0 1.04E+07 1.85E+07 - - - 2.9283 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.19749.19749.2 0.000394 16-Oct K.TMTLFSALR[166.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 1048.5615 0.68 24738 19749 2 1048.564893 525.288 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.41 3720.1 - 1.21E+06 - - - 3.2626 - 1.784 0.406 - 381.5 1 2 0 0.0034 9 0 0 0 4.76E+06 6.99E+06 - - - 3.7133 1 230117_WJC_METTL3_WT_vs_EV_F03.19751.19751.2 3.47E-06 14/22 K.ALEDAFLAIDAK[136.11].L sp|O15355|PPM1G_HUMAN 1 1283.6853 2.75 24740 19751 2 1283.686028 642.8499 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.03 3720.4 - 845289 - - - 0.592 - 2.576 0.484 - 537.5 1 2 0 0.0008 12 0 0 0 1.88E+07 6.86E+06 - - - 5.1053 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.19754.19754.2 0.0338 12-Jun K.DAFLVFR.S "sp|Q9Y6D6|BIG1_HUMAN,sp|Q9Y6D5|BIG2_HUMAN,tr|A0A7P0T7Z2|A0A7P0T7Z2_HUMAN,tr|A0A7P0T9L9|A0A7P0T9L9_HUMAN,tr|A0A7P0TA34|A0A7P0TA34_HUMAN,tr|A0A7P0T9L6|A0A7P0T9L6_HUMAN" 6 866.465 1.33 24743 19754 2 866.465662 434.2398 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens OX=9606 GN=ARFGEF1 PE=1 SV=2 5.84 3720.8 - 492950 - - - 0.7202 - 1.277 0.297 - 101 1 2 0 0.0006 7 0 0 0 2.13E+06 1.60E+06 - - - 2.0092 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19756.19756.2 0.341 18-Nov R.VDLPLAVLSK.M "sp|Q9H773|DCTP1_HUMAN,tr|H3BSA6|H3BSA6_HUMAN" 2 1053.6434 16.89 24745 19756 2 1053.644024 527.829 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 5.81 3721 - 384361 - - - 0.5951 - 2.178 0.379 - 293.7 1 2 0 0.0006 10 0 0 0 4.59E+07 2.72E+06 - - - 4.0129 0.9965 230117_WJC_METTL3_WT_vs_EV_F03.19757.19757.2 0.551 14-Oct R.LAWALALR[166.11].G sp|Q92621|NU205_HUMAN 1 922.5628 2.62 24746 19757 2 922.564961 462.2887 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 9.75 3721.1 - 335222 - - - 2.3511 - 1.519 0.156 - 322.6 1 2 0 0.0022 8 0 0 0 4.64E+06 1.77E+06 - - - 1.4534 1 230117_WJC_METTL3_WT_vs_EV_F03.19761.19761.2 0.000145 18-Nov R.GPILLPYQFR.M "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1202.6812 1.01 24749 19761 2 1202.6858 602.3479 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 8.75 3721.7 - 1.31E+06 - - - 3.8422 - 2.063 0.495 - 497.1 1 2 0 0.0046 10 0 0 0 8.08E+06 7.99E+06 - - - 4.717 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.19763.19763.2 0.0132 18-Aug K.ELLGQGLLLR.S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1110.6761 0.92 24750 19763 2 1110.676598 556.3453 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3721.9 - 5.56E+06 - - - 0.4538 - 1.651 0.214 - 255.8 1 2 0 0.0005 10 0 0 0 1.36E+08 1.47E+08 - - - 2.021 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.19764.19764.2 0.121 20-Jul R.VLLQAFDVVER[166.11].S sp|Q15750|TAB1_HUMAN 1 1297.727 0.44 24751 19764 2 1297.726245 649.8708 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 OS=Homo sapiens OX=9606 GN=TAB1 PE=1 SV=1 4.37 3721.9 - 1.61E+06 - - - -0.5487 - 1.741 0.226 - 138.8 2 2 0 -0.0007 11 0 0 0 1.45E+07 3.27E+07 - - - 2.0755 0.9473 230117_WJC_METTL3_WT_vs_EV_F03.19765.19765.2 0.0715 12-Sep L.PDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 946.4661 1.38 24752 19765 2 946.466197 474.2403 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 6.27 3722 - 2.20E+06 - - - 0.1014 - 1.825 0.308 - 343.5 1 1 0 0.0001 7 0 0 0 2.95E+07 2.14E+07 - - - 3.222 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.19767.19767.2 0.012 13/22 K.LANILFTQELAR.R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1387.7823 1.35 24754 19767 2 1387.780396 694.8985 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3722.1 - 1.26E+06 - - - -1.408 - 2.91 0.244 - 722.4 1 2 0 -0.002 12 0 0 0 2.99E+07 2.22E+07 - - - 3.6531 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.19768.19768.2 0.0139 15/22 K.LANILFTQELAR[166.11].R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1397.7906 1.35 24755 19768 2 1397.78838 699.9026 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3722.2 - 1.13E+06 - - - -1.6025 - 2.709 0.303 - 1019.3 1 2 0 -0.0022 12 0 0 0 2.99E+07 2.22E+07 - - - 3.9004 1 230117_WJC_METTL3_WT_vs_EV_F03.19769.19769.2 7.96E-06 20-Dec K.SFYGSTLFLC[160.03]R.R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1349.6438 1.31 24756 19769 2 1349.639629 675.8292 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 7.94 3722.3 - 655172 - - - -3.0964 - 2.239 0.568 - 488.4 1 2 0 -0.0042 11 0 0 0 8.20E+06 6.25E+06 - - - 5.4154 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19770.19770.2 0.00146 20-Sep K.SFYGSTLFLC[160.03]R[166.11].R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1359.6521 1.31 24757 19770 2 1359.653985 680.8333 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 7.94 3722.5 - 548610 - - - 1.4026 - 1.771 0.341 - 218 1 2 0 0.0019 11 0 0 0 8.20E+06 6.25E+06 - - - 3.1052 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.19771.19771.2 0.000779 20-Dec K.ALLLSSVLSEK.G "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1158.686 2.98 24758 19771 2 1158.6842 580.3503 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 6.05 3722.6 - 405534 - - - -1.5449 - 2.391 0.376 - 451.4 1 2 0 -0.0018 11 0 0 0 1.39E+07 4.66E+06 - - - 4.1758 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.19772.19772.2 0.00065 18-Oct K.QLEDILVLAK[136.11].Q "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A0A6YYJ5|A0A0A6YYJ5_HUMAN" 8 1148.6896 4.42 24759 19772 2 1148.688694 575.3521 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.37 3722.7 - 0 - - - -0.8105 - 1.857 0.424 - 261.5 1 2 0 -0.0009 10 0 0 0 2.31E+07 5.22E+06 - - - 3.9001 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19773.19773.2 0.301 20-Oct K.ALLLSSVLSEK[136.11].G "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1166.7002 -1 24760 19773 2 1166.701825 584.3574 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 6.05 3722.9 - 0 - - - 1.4014 - 2.181 0.236 - 238.7 1 2 0 0.0016 11 0 0 0 0.00E+00 0.00E+00 - - - 2.8931 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19774.19774.2 0.00601 16-Oct R.ILDTLGLLR[166.11].Q "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN,tr|A0A087WWF4|A0A087WWF4_HUMAN" 3 1022.6364 1.21 24761 19774 2 1022.639167 512.3255 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 5.84 3723 - 204547 - - - 2.7537 - 1.923 0.338 - 242.3 1 2 0 0.0028 9 0 0 0 3.25E+07 2.68E+07 - - - 3.4283 1 230117_WJC_METTL3_WT_vs_EV_F03.19775.19775.2 0.000507 16-Nov R.ILDTLGLLR.Q "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN,tr|A0A087WWF4|A0A087WWF4_HUMAN" 3 1012.6281 1.21 24762 19775 2 1012.631851 507.3213 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 5.84 3723.1 - 0 - - - 3.723 - 2.381 0.423 - 310.1 1 2 0 0.0038 9 0 0 0 3.25E+07 2.68E+07 - - - 4.6739 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19776.19776.2 0.0023 20-Aug K.IESLPPLLIGK[136.11].F "sp|Q8N9N7|LRC57_HUMAN,tr|A0A3B3ISV5|A0A3B3ISV5_HUMAN,tr|H3BSW0|H3BSW0_HUMAN" 3 1186.7417 2.44 24763 19776 2 1186.742741 594.3781 Leucine-rich repeat-containing protein 57 OS=Homo sapiens OX=9606 GN=LRRC57 PE=1 SV=1 6 3723.2 - 0 - - - 0.9101 - 1.564 0.438 - 139.1 1 2 0 0.0011 11 0 0 0 7.61E+06 3.12E+06 - - - 3.4856 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19784.19784.2 0.0171 22-Sep K.YLGPAVLMQAYR.W sp|P21912|SDHB_HUMAN 1 1380.7224 1.69 24769 19784 2 1380.724322 691.3685 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 8.59 3724.3 - 255826 - - - 1.3978 - 1.851 0.296 - 178.7 1 2 0 0.0019 12 0 0 0 4.57E+06 2.71E+06 - - - 2.8467 1 230117_WJC_METTL3_WT_vs_EV_F03.19787.19787.2 3.29E-07 14/22 K.IYDALDVSLIER.G sp|P54136|SYRC_HUMAN 1 1405.7453 1.45 24770 19787 2 1405.746328 703.8799 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.03 3724.7 - 5.05E+06 - - - 0.7341 - 2.842 0.571 - 889.9 1 2 0 0.001 12 0 0 0 2.96E+07 2.04E+07 - - - 6.0064 1 230117_WJC_METTL3_WT_vs_EV_F03.19790.19790.2 0.000649 13/22 K.IYDALDVSLIER[166.11].G sp|P54136|SYRC_HUMAN 1 1415.7536 1.45 24773 19790 2 1415.754611 708.8841 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.03 3725 - 3.95E+06 - - - 0.7381 - 2.733 0.486 - 699.7 1 2 0 0.001 12 0 0 0 2.96E+07 2.04E+07 - - - 5.2756 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19793.19793.2 0.0945 14-Aug R.MGLLAVLR.S "sp|O95394|AGM1_HUMAN,tr|D6RF77|D6RF77_HUMAN,tr|D6RC77|D6RC77_HUMAN,tr|D6RCQ8|D6RCQ8_HUMAN,tr|A0A494C099|A0A494C099_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C163|A0A494C163_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|D6RCD1|D6RCD1_HUMAN" 9 871.5313 2.19 24776 19793 2 871.533033 436.7729 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 9.5 3725.4 - 1.41E+06 - - - 1.938 - 1.975 0.315 - 217.2 1 2 0 0.0017 8 0 0 0 4.26E+06 1.95E+06 - - - 3.4196 0.9862 230117_WJC_METTL3_WT_vs_EV_F03.19794.19794.3 5.62E-05 13/48 R.GAAGALLVYDITR.R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1318.7245 1.21 24777 19794 3 1318.728272 440.5821 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3725.5 - 1.39E+06 - - - 2.8596 - 2.301 0.071 - 275.2 1 2 0 0.0038 13 0 0 0 4.31E+06 3.57E+06 - - - 1.59 0.9854 230117_WJC_METTL3_WT_vs_EV_F03.19795.19795.2 0.189 12-Jun R.LQLWAFK.L sp|Q9Y613|FHOD1_HUMAN 1 904.5171 1.13 24778 19795 2 904.520094 453.2658 FH1\FH2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FHOD1 PE=1 SV=3 8.75 3725.6 - 853598 - - - 3.3388 - 1.335 0.112 - 95.5 1 2 0 0.003 7 0 0 0 2.56E+06 2.26E+06 - - - 0.7828 0.989 230117_WJC_METTL3_WT_vs_EV_F03.19796.19796.3 0.407 Sep-48 R.LVDIIAAVPPQYR.K "sp|Q9H9T3|ELP3_HUMAN,tr|E5RIZ7|E5RIZ7_HUMAN,tr|E5RIC0|E5RIC0_HUMAN,tr|E5RHY2|E5RHY2_HUMAN,tr|E5RHR2|E5RHR2_HUMAN" 5 1453.8293 3.26 24779 19796 3 1453.829316 485.617 Elongator complex protein 3 OS=Homo sapiens OX=9606 GN=ELP3 PE=1 SV=2 5.84 3725.8 - 847241 - - - 0.011 - 1.777 0.139 - 117.2 1 2 0 0 13 0 0 0 2.05E+06 6.28E+05 - - - 1.6485 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19803.19803.2 9.02E-07 15/24 R.GAAGALLVYDITR[166.11].R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1328.7328 3 24785 19803 2 1328.736461 665.3737 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3726.7 - 818416 - - - 2.7771 - 3.429 0.214 - 1076 1 2 0 0.0037 13 0 0 0 1.83E+08 6.10E+07 - - - 3.7831 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19805.19805.2 0.00195 18-Sep K.GIYLWDVEGR[166.11].K sp|P04181|OAT_HUMAN 1 1216.6116 1.08 24787 19805 2 1216.610933 609.3131 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.37 3726.9 - 474431 - - - -0.5425 - 1.812 0.424 - 241.9 1 2 0 -0.0007 10 0 0 0 6.68E+06 6.20E+06 - - - 3.8317 0.96 230117_WJC_METTL3_WT_vs_EV_F03.19807.19807.2 0.976 14-May R.NIPMLFVR.G sp|P62310|LSM3_HUMAN 1 988.5528 1.86 24788 19807 2 988.55426 495.2837 U6 snRNA-associated Sm-like protein LSm3 OS=Homo sapiens OX=9606 GN=LSM3 PE=1 SV=2 9.75 3727.1 - 555793 - - - 1.4688 - 1.072 0.077 - 76.6 4 2 0 0.0015 8 0 0 0 3.11E+07 1.67E+07 - - - -0.45 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19810.19810.2 0.00038 22-Nov K.YLGPAVLMQAYR.W sp|P21912|SDHB_HUMAN 1 1380.7224 1.69 24790 19810 2 1380.723439 691.3685 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 8.59 3727.4 - 218555 - - - 0.7583 - 1.918 0.425 - 334.5 1 2 0 0.001 12 0 0 0 4.57E+06 2.71E+06 - - - 3.8934 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.19814.19814.2 0.000901 20-Nov R.NAVLAIYTIYR[166.11].N "sp|P53618|COPB_HUMAN,tr|E9PP73|E9PP73_HUMAN" 2 1305.732 5.2 24794 19814 2 1305.727654 653.8733 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 8.59 3727.8 - 0 - - - -3.3606 - 2.526 0.394 - 591 1 2 0 -0.0044 11 0 0 0 3.43E+07 6.60E+06 - - - 4.4565 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19816.19816.2 0.000274 18-Oct K.GIYLWDVEGR.K sp|P04181|OAT_HUMAN 1 1206.6033 1.08 24795 19816 2 1206.603109 604.3089 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.37 3728 - 694394 - - - -0.1774 - 1.916 0.471 - 342.2 1 2 0 -0.0002 10 0 0 0 6.68E+06 6.20E+06 - - - 4.3348 1 230117_WJC_METTL3_WT_vs_EV_F03.19818.19818.2 0.0017 13/24 R.LLLFSSATDAAIR.V "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1376.7664 0.44 24796 19818 2 1376.766337 689.3905 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.84 3728.2 - 433131 - - - -0.0211 - 2.688 0.529 - 617.1 1 2 0 0 13 0 0 0 9.77E+06 2.25E+07 - - - 5.486 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.19819.19819.2 0.0145 14-Jul R.SLPVFPFR.E "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 961.5385 1.37 24797 19819 2 961.539299 481.7765 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 9.47 3728.3 - 169552 - - - 0.7914 - 1.368 0.307 - 178.1 1 2 0 0.0008 8 0 0 0 9.51E+06 6.94E+06 - - - 2.2533 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.19820.19820.2 0.021 14-Jul R.NLIEWLNK.Y sp|Q96DG6|CMBL_HUMAN 1 1028.5655 0.83 24798 19820 2 1028.567028 515.29 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 6 3728.4 - 3.55E+06 - - - 1.504 - 1.454 0.225 - 166.4 1 2 0 0.0015 8 0 0 0 2.11E+08 2.54E+08 - - - 1.8313 1 230117_WJC_METTL3_WT_vs_EV_F03.19821.19821.3 6.09E-07 14/60 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 77.45 24799 19821 3 1787.007034 596.6753 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3728.4 - 1.44E+06 - - - 1.681 - 2.827 0.56 - 356 1 2 0 0.003 16 0 0 0 3.78E+08 4.88E+06 - - - 7.4491 1 230117_WJC_METTL3_WT_vs_EV_F03.19822.19822.2 8.10E-07 23/30 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 999 24800 19822 2 1787.005393 894.5093 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3728.5 - 1.39E+06 - - - 0.7627 - 4.422 0.594 - 1859.2 1 2 0 0.0014 16 0 0 0 8.47E+07 0.00E+00 - - - 7.0827 0.9704 230117_WJC_METTL3_WT_vs_EV_F03.19823.19823.2 0.525 12-Jun K.LLDDLFR[166.11].K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 900.4944 0.97 24801 19823 2 900.493386 451.2545 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3728.6 - 378528 - - - -1.1682 - 1.253 0.097 - 95.2 1 2 0 -0.0011 7 0 0 0 2.19E+08 2.25E+08 - - - 0.4717 0.9604 230117_WJC_METTL3_WT_vs_EV_F03.19824.19824.2 0.0159 22-Oct K.PYRPWGTEIGAF.- "sp|Q9Y5J3|HEY1_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 4 1392.6826 2.29 24802 19824 2 1392.684027 697.3486 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 6.43 3728.7 - 256591 - - - 0.9988 - 1.804 0.354 - 292.4 1 1 0 0.0014 12 0 0 0 8.85E+06 3.87E+06 - - - 3.2076 0.9421 230117_WJC_METTL3_WT_vs_EV_F03.19825.19825.2 0.987 14-May R.SLPVFPFR[166.11].E "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 971.5468 2.07 24803 19825 2 971.544058 486.7807 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 9.47 3728.9 - 135694 - - - -2.8305 - 1.149 0.171 - 72.5 1 2 0 -0.0027 8 0 0 0 7.70E+06 3.71E+06 - - - 0.722 0.9966 230117_WJC_METTL3_WT_vs_EV_F03.19830.19830.2 0.422 12-Jul K.LLDDLFR.K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 890.4862 0.98 24806 19830 2 890.487185 446.2504 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3729.5 - 7.02E+06 - - - 1.1421 - 1.301 0.191 - 158.7 1 2 0 0.001 7 0 0 0 2.18E+08 2.22E+08 - - - 1.2852 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19831.19831.2 0.0222 18-Nov K.IINFAPSLLR[166.11].L "sp|O15397|IPO8_HUMAN,tr|F5H2I3|F5H2I3_HUMAN" 2 1152.6894 1.29 24807 19831 2 1152.692244 577.352 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 9.75 3729.6 - 4.29E+06 - - - 2.4248 - 2.29 0.38 - 328.7 1 2 0 0.0028 10 0 0 0 5.18E+07 4.00E+07 - - - 4.1595 0.999 230117_WJC_METTL3_WT_vs_EV_F03.19832.19832.2 0.01 14/24 R.AGLNGLQLAVLAR.L sp|Q96S55|WRIP1_HUMAN 1 1294.7721 7.08 24808 19832 2 1294.772431 648.3933 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 9.79 3729.7 - 2.25E+06 - - - 0.2402 - 2.554 0.173 - 763.9 1 2 0 0.0003 13 0 0 0 1.31E+07 1.86E+06 - - - 2.7252 0.9928 230117_WJC_METTL3_WT_vs_EV_F03.19833.19833.2 0.393 18-Jul R.AAFVLPEFAR.K "sp|P19623|SPEE_HUMAN,tr|K7EL89|K7EL89_HUMAN" 2 1119.6077 5.4 24809 19833 2 1119.606291 560.8111 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 6.05 3729.8 - 1.42E+06 - - - -1.2406 - 1.575 0.175 - 103.7 1 2 0 -0.0014 10 0 0 0 9.41E+07 1.74E+07 - - - 1.6011 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.19834.19834.2 0.07 12-Jun R.WLSQYID.- "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 923.4389 - 24810 19834 2 923.439626 462.7267 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.3 3729.9 - 1.26E+06 - - - 0.8046 - 1.181 0.204 - 90.2 1 2 0 0.0007 7 0 0 0 - - - - - 1.0746 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.19838.19838.3 0.0734 Dec-52 K.IFTPIVEHLGLQIR[166.11].F "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 1644.9591 2.08 24814 19838 3 1644.961165 549.327 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 6.75 3730.4 - 855263 - - - 1.2663 - 1.574 0.274 - 101.6 1 2 0 0.0021 14 0 0 0 6.96E+06 3.35E+06 - - - 2.7998 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19840.19840.2 2.59E-05 18-Nov R.SPVTFLSDLR.S sp|A5YKK6|CNOT1_HUMAN 1 1133.6081 2.13 24816 19840 2 1133.608198 567.8113 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 5.55 3730.6 - 744408 - - - 0.1094 - 2.252 0.395 - 364.2 1 2 0 0.0001 10 0 0 0 7.21E+06 3.39E+06 - - - 4.2245 1 230117_WJC_METTL3_WT_vs_EV_F03.19842.19842.2 9.68E-06 14/20 K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 -1 24818 19842 2 1184.717675 593.3637 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3730.9 - 519251 - - - 4.0533 - 2.65 0.531 - 763.9 1 2 0 0.0048 11 0 0 0 0.00E+00 0.00E+00 - - - 5.5979 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19848.19848.2 0.477 20-Oct -.MLLFVEQVASK.G "sp|Q71RC2|LARP4_HUMAN,tr|F8W1Z5|F8W1Z5_HUMAN" 2 1263.6897 0.36 24822 19848 2 1263.692112 632.8521 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 5.75 3731.6 - 2.33E+06 - - - 1.9127 - 2.151 0.356 - 293.5 1 2 0 0.0024 11 0 0 0 2.02E+07 5.62E+07 - - - 3.7417 1 230117_WJC_METTL3_WT_vs_EV_F03.19849.19849.2 1.31E-06 13/20 R.WGAFAQSILER[166.11].G sp|Q13472|TOP3A_HUMAN 1 1286.6647 0.01 24823 19849 2 1286.664871 644.3396 DNA topoisomerase 3-alpha OS=Homo sapiens OX=9606 GN=TOP3A PE=1 SV=1 6 3731.8 - 2.03E+06 - - - 0.1399 - 2.654 0.558 - 780.1 1 2 0 0.0002 11 0 0 0 8.49E+04 1.33E+07 - - - 5.8028 0.9957 230117_WJC_METTL3_WT_vs_EV_F03.19851.19851.2 0.0526 14-Jul R.DWVLNEFK.H "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1049.5182 1.65 24825 19851 2 1049.51801 525.7664 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3731.9 - 1.70E+06 - - - -0.1772 - 1.38 0.199 - 209.7 1 2 0 -0.0002 8 0 0 0 1.26E+08 7.65E+07 - - - 1.4821 1 230117_WJC_METTL3_WT_vs_EV_F03.19852.19852.2 1.29E-05 18-Dec R.QEVVDLLLAR[166.11].G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1164.6742 1.28 24826 19852 2 1164.67646 583.3444 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3732.1 - 1.63E+06 - - - 1.9465 - 2.487 0.538 - 727.7 1 2 0 0.0023 10 0 0 0 9.63E+07 7.51E+07 - - - 5.557 1 230117_WJC_METTL3_WT_vs_EV_F03.19855.19855.2 0.000707 24-Nov R.VETPVLPPVLVPR.H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1414.8548 2.16 24829 19855 2 1414.85564 708.4347 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3732.4 - 1.07E+06 - - - 0.6029 - 2.16 0.546 - 212.3 1 2 0 0.0009 13 0 0 0 2.66E+07 1.23E+07 - - - 5.05 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19857.19857.2 7.52E-05 24-Oct R.VETPVLPPVLVPR[166.11].H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1424.8631 2.16 24831 19857 2 1424.865583 713.4388 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3732.7 - 641209 - - - 1.7728 - 1.961 0.465 - 251.9 1 2 0 0.0025 13 0 0 0 2.66E+07 1.23E+07 - - - 4.2031 0.9538 230117_WJC_METTL3_WT_vs_EV_F03.19858.19858.2 0.408 14-Aug K.GIILFISR.N "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 917.5698 0.76 24832 19858 2 917.567493 459.7922 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3732.8 - 1.39E+06 - - - -2.5557 - 1.224 0.152 - 183.6 1 2 0 -0.0023 8 0 0 0 4.01E+06 5.27E+06 - - - 0.7725 1 230117_WJC_METTL3_WT_vs_EV_F03.19862.19862.2 0.00144 13/20 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 169.76 24835 19862 2 1276.704249 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3733.3 - 1.28E+08 - - - 1.2109 - 2.722 0.388 - 902 1 2 0 0.0015 11 0 0 0 1.15E+09 6.80E+06 - - - 4.6152 1 230117_WJC_METTL3_WT_vs_EV_F03.19864.19864.2 4.18E-08 20-Dec K.TAVETAVLLLR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1194.7211 9.2 24836 19864 2 1194.724187 598.3678 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3733.5 - 2.81E+06 - - - 2.5479 - 2.751 0.55 - 465.9 1 2 0 0.003 11 0 0 0 3.33E+09 3.62E+08 - - - 5.8399 1 230117_WJC_METTL3_WT_vs_EV_F03.19865.19865.2 3.51E-05 16-Oct K.YDWDLLAAR[166.11].S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1131.5588 1.81 24837 19865 2 1131.561457 566.7867 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3733.6 - 1.51E+06 - - - 2.3225 - 2.082 0.504 - 419.6 1 2 0 0.0026 9 0 0 0 1.11E+08 6.11E+07 - - - 4.8843 0.999 230117_WJC_METTL3_WT_vs_EV_F03.19866.19866.3 0.0815 Sep-40 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 2.91 24838 19866 3 1276.703378 426.5748 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3733.7 - 1.75E+06 - - - 0.5287 - 1.926 0.253 - 166.5 1 2 0 0.0007 11 0 0 0 6.81E+06 2.34E+06 - - - 3.2225 1 230117_WJC_METTL3_WT_vs_EV_F03.19867.19867.2 9.01E-08 13/26 K.FYGPAGPYGIFAGR.D sp|O15173|PGRC2_HUMAN 1 1471.7248 1.51 24839 19867 2 1471.726542 736.8697 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3733.8 - 1.41E+06 - - - 1.1599 - 2.226 0.489 - 577.6 1 2 0 0.0017 14 0 0 0 4.03E+07 2.67E+07 - - - 4.6603 1 230117_WJC_METTL3_WT_vs_EV_F03.19868.19868.2 2.33E-07 13/26 K.FYGPAGPYGIFAGR[166.11].D sp|O15173|PGRC2_HUMAN 1 1481.7331 1.51 24840 19868 2 1481.732772 741.8738 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3733.9 - 1.26E+06 - - - -0.2247 - 2.323 0.587 - 639.8 1 2 0 -0.0003 14 0 0 0 4.03E+07 2.67E+07 - - - 5.4916 0.9678 230117_WJC_METTL3_WT_vs_EV_F03.19872.19872.2 0.00085 22-Sep K.PYR[166.11]PWGTEIGAF.- "sp|Q9Y5J3|HEY1_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 4 1402.6909 2.28 24844 19872 2 1402.693861 702.3527 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 6.43 3734.4 - 561215 - - - 2.1067 - 1.92 0.403 - 218.3 1 1 0 0.003 12 0 0 0 8.72E+06 3.82E+06 - - - 3.733 0.9906 230117_WJC_METTL3_WT_vs_EV_F03.19874.19874.2 1.7 12-Jul K.DIILPFR.V "sp|Q96CW1|AP2M1_HUMAN,tr|A0A087WY71|A0A087WY71_HUMAN,tr|C9JJ47|C9JJ47_HUMAN,tr|E9PFW3|E9PFW3_HUMAN" 4 872.512 1.6 24846 19874 2 872.513496 437.2633 AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2 5.84 3734.7 - 194275 - - - 1.7272 - 1.603 0 - 208.5 1 2 0 0.0015 7 0 0 0 2.97E+07 1.85E+07 - - - 0.5357 1 230117_WJC_METTL3_WT_vs_EV_F03.19876.19876.2 5.05E-08 28-Dec R.LYGPSSVSFADDFVR.S "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 1658.794 999 24848 19876 2 1658.79035 830.4043 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.21 3734.9 - 118816 - - - -2.2227 - 2.403 0.573 - 349.2 1 2 0 -0.0037 15 0 0 0 1.38E+06 0.00E+00 - - - 5.4275 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19879.19879.2 0.000456 16-Aug K.FFPLIEVNK.V "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1105.6172 0.82 24850 19879 2 1105.617897 553.8159 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6 3735.3 - 1.60E+07 - - - 0.6467 - 1.632 0.505 - 175.6 1 2 0 0.0007 9 0 0 0 2.55E+08 3.10E+08 - - - 4.1877 1 230117_WJC_METTL3_WT_vs_EV_F03.19881.19881.2 6.73E-06 16-Sep K.YDWDLLAAR.S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1121.5506 1.8 24852 19881 2 1121.551429 561.7826 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3735.4 - 6.46E+06 - - - 0.7757 - 1.853 0.545 - 337.4 1 2 0 0.0009 9 0 0 0 1.12E+08 6.20E+07 - - - 4.8505 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19882.19882.2 0.000797 18-Jul R.QEVVDLLLAR.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1154.6659 1.28 24853 19882 2 1154.666335 578.3402 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3735.5 - 4.39E+06 - - - 0.3568 - 1.651 0.458 - 238 1 2 0 0.0004 10 0 0 0 9.63E+07 7.51E+07 - - - 3.8232 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.19883.19883.3 0.00027 14/40 K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 8.92 24854 19883 3 1184.712995 395.9116 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3735.5 - 3.19E+06 - - - 0.103 - 2.488 0.397 - 297.6 1 2 0 0.0001 11 0 0 0 8.62E+07 9.67E+06 - - - 5.5555 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19885.19885.2 0.0257 14-Aug R.IWYLLDGK[136.11].M "sp|Q9BYD1|RM13_HUMAN,tr|E5RFI2|E5RFI2_HUMAN" 2 1014.563 0.87 24856 19885 2 1014.564173 508.2888 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 5.83 3735.6 - 2.32E+06 - - - 1.1877 - 1.763 0.366 - 196.2 1 2 0 0.0012 8 0 0 0 1.40E+07 1.60E+07 - - - 3.454 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.19886.19886.2 0.339 18-Jul K.IINFAPSLLR.L "sp|O15397|IPO8_HUMAN,tr|F5H2I3|F5H2I3_HUMAN" 2 1142.6812 1.29 24857 19886 2 1142.685323 572.3479 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 9.75 3735.7 - 1.45E+06 - - - 3.6266 - 1.601 0.28 - 129.4 1 2 0 0.0041 10 0 0 0 5.18E+07 4.00E+07 - - - 2.4214 0.955 230117_WJC_METTL3_WT_vs_EV_F03.19888.19888.2 0.408 16-Jul R.LLELFPVNR.Q "sp|Q9Y6E2|BZW2_HUMAN,tr|B5MCH7|B5MCH7_HUMAN,tr|E9PFD4|E9PFD4_HUMAN,tr|E7ETZ4|E7ETZ4_HUMAN,tr|B5MCE7|B5MCE7_HUMAN,tr|Q75MG1|Q75MG1_HUMAN" 6 1099.639 1.97 24859 19888 2 1099.63553 550.8268 Basic leucine zipper and W2 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=BZW2 PE=1 SV=1 6 3735.9 - 1.20E+06 - - - -3.1374 - 1.467 0.142 - 167.2 2 2 0 -0.0035 9 0 0 0 4.24E+07 2.15E+07 - - - 1.0629 1 230117_WJC_METTL3_WT_vs_EV_F03.19890.19890.2 7.12E-06 14/20 K.FDGILGMAYPR.L "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1238.6118 8.98 24861 19890 2 1238.611302 620.3132 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.84 3736.1 - 816337 - - - -0.3851 - 2.382 0.462 - 833.8 1 2 0 -0.0005 11 0 0 0 3.40E+07 3.78E+06 - - - 4.8012 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19891.19891.2 5.62E-05 14/24 R.AIVFVVDSAAFQR.E "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1421.7667 1.84 24862 19891 2 1421.76683 711.8906 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.88 3736.2 - 773232 - - - 0.0914 - 2.711 0.391 - 828.9 1 2 0 0.0001 13 0 0 0 6.45E+06 3.51E+06 - - - 4.4885 0.9712 230117_WJC_METTL3_WT_vs_EV_F03.19898.19898.2 0.000173 20-Nov K.FEQLVSIGSSY.N sp|Q9NXV2|KCTD5_HUMAN 1 1228.5976 - 24867 19898 2 1228.598513 615.3061 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4 3737.1 - 501165 - - - 0.7684 - 1.667 0.46 - 380.7 1 1 0 0.0009 11 0 0 0 - - - - - 3.8207 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19901.19901.3 0.0024 Dec-40 K.TAVETAVLLLR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1194.7211 8.89 24870 19901 3 1194.724036 399.2477 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3737.5 - 550803 - - - 2.4215 - 2.088 0.35 - 197 1 2 0 0.0029 11 0 0 0 8.60E+07 9.67E+06 - - - 4.5328 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.19903.19903.2 0.00121 20-Dec K.TYSYLTPDLWK.E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1385.6867 0.35 24872 19903 2 1385.689231 693.8506 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.5 3737.8 - 337726 - - - 1.8135 - 1.819 0.365 - 398.2 1 2 0 0.0025 11 0 0 0 3.99E+06 1.16E+07 - - - 3.3546 0.9831 230117_WJC_METTL3_WT_vs_EV_F03.19906.19906.3 0.239 Sep-40 R.LIHPVQFVFLR.K "sp|Q2TAA5|ALG11_HUMAN,tr|A0A7P0T8Y4|A0A7P0T8Y4_HUMAN,tr|A0A3B3IS90|A0A3B3IS90_HUMAN" 3 1367.8078 1.04 24875 19906 3 1367.812556 456.9432 "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Homo sapiens OX=9606 GN=ALG11 PE=1 SV=2" 9.76 3738.2 - 198791 - - - 3.4939 - 1.627 0.161 - 126.4 1 2 0 0.0048 11 0 0 0 2.25E+06 2.17E+06 - - - 1.7164 0.998 230117_WJC_METTL3_WT_vs_EV_F03.19907.19907.2 0.16 20-Oct R.IAIQGIITAIK[136.11].Y sp|Q6NSI4|RADX_HUMAN 1 1147.742 2.2 24876 19907 2 1147.741054 574.8783 RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2 8.75 3738.3 - 130543 - - - -0.8199 - 1.898 0.245 - 158.8 1 2 0 -0.0009 11 0 0 0 1.07E+07 4.85E+06 - - - 2.5838 0.9611 230117_WJC_METTL3_WT_vs_EV_F03.19914.19914.2 11.4 12-Jun K.DIILPFR[166.11].V "sp|Q96CW1|AP2M1_HUMAN,tr|A0A087WY71|A0A087WY71_HUMAN,tr|C9JJ47|C9JJ47_HUMAN,tr|E9PFW3|E9PFW3_HUMAN" 4 882.5203 1.62 24881 19914 2 882.520745 442.2674 AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2 5.84 3738.9 - 2.37E+06 - - - 0.5507 - 1.214 0 - 172.7 1 2 0 0.0005 7 0 0 0 3.00E+07 1.85E+07 - - - -0.3447 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.19915.19915.2 0.132 20-Aug R.IAIQGIITAIK.Y sp|Q6NSI4|RADX_HUMAN 1 1139.7278 2.2 24882 19915 2 1139.727783 570.8712 RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2 8.75 3739 - 1.93E+06 - - - -0.0105 - 1.582 0.357 - 119.5 1 2 0 0 11 0 0 0 1.07E+07 4.85E+06 - - - 2.9187 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.19920.19920.2 0.00501 28-Jul R.LTPSASLPPAQLLLR.A "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 1575.9348 1.68 24887 19920 2 1575.935625 788.9747 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 9.75 3739.5 - 575892 - - - 0.5057 - 1.502 0.392 - 81.1 1 2 0 0.0008 15 0 0 0 2.66E+06 1.58E+06 - - - 2.9362 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.19926.19926.2 0.0242 12-Jun K.NMFAIWR.V "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 936.464 1.04 24891 19926 2 936.466088 469.2393 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3740.2 - 1.30E+06 - - - 2.2371 - 1.183 0.326 - 116.8 1 2 0 0.0021 7 0 0 0 4.82E+07 4.65E+07 - - - 1.9807 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.19929.19929.2 4.96 12-Jul R.VTLLLFK.D "sp|Q9Y3C4|TPRKB_HUMAN,sp|Q86YN1|DOPP1_HUMAN,tr|H7C1Z8|H7C1Z8_HUMAN,tr|H7BXT6|H7BXT6_HUMAN" 4 832.5422 1.72 24894 19929 2 832.543728 417.2784 EKC\KEOPS complex subunit TPRKB OS=Homo sapiens OX=9606 GN=TPRKB PE=1 SV=1 8.72 3740.6 - 738711 - - - 1.8041 - 1.588 0.076 - 196.6 1 2 0 0.0015 7 0 0 0 6.01E+06 3.49E+06 - - - 1.0672 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19930.19930.2 0.00011 18-Sep R.LWGDIYFNPK.T sp|Q15029|U5S1_HUMAN 1 1251.6288 1.37 24895 19930 2 1251.62954 626.8217 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.83 3740.7 - 681970 - - - 0.584 - 1.819 0.514 - 265 1 2 0 0.0007 10 0 0 0 1.58E+07 1.15E+07 - - - 4.5072 0.9912 230117_WJC_METTL3_WT_vs_EV_F03.19932.19932.2 1.29 12-Jun K.DFLLSLK[136.11].T sp|Q86UP2|KTN1_HUMAN 1 842.4993 1.18 24897 19932 2 842.500259 422.2569 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.84 3741 - 426677 - - - 1.1323 - 1.407 0.06 - 133.2 1 2 0 0.001 7 0 0 0 4.07E+06 3.46E+06 - - - 0.5658 1 230117_WJC_METTL3_WT_vs_EV_F03.19935.19935.2 0.0188 18-Dec R.DAVLLVFANK.Q "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 5 1088.623 1.99 24899 19935 2 1088.625586 545.3188 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 5.84 3741.4 - 1.40E+07 - - - 2.3792 - 2.476 0.418 - 744.1 1 2 0 0.0026 10 0 0 0 2.23E+08 1.13E+08 - - - 4.6583 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19937.19937.2 0.000105 18-Oct R.LLVVYPWTQR.F "sp|P69892|HBG2_HUMAN,sp|P69891|HBG1_HUMAN,sp|P02042|HBD_HUMAN,sp|P02100|HBE_HUMAN,sp|P68871|HBB_HUMAN,tr|A0A2R8Y7R2|A0A2R8Y7R2_HUMAN,tr|E9PEW8|E9PEW8_HUMAN,tr|E9PFT6|E9PFT6_HUMAN,tr|F8W6P5|F8W6P5_HUMAN,tr|A0A2R8Y7X9|A0A2R8Y7X9_HUMAN" 10 1273.7183 999 24900 19937 2 1273.718276 637.8664 Hemoglobin subunit gamma-2 OS=Homo sapiens OX=9606 GN=HBG2 PE=1 SV=2 8.75 3741.6 - 4.68E+06 - - - -0.0133 - 2.077 0.339 - 467.8 1 2 0 0 10 0 0 0 6.79E+07 0.00E+00 - - - 3.5851 0.9967 230117_WJC_METTL3_WT_vs_EV_F03.19939.19939.2 0.431 14-Aug R.SLLSILQR.S "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 928.5706 2.24 24902 19939 2 928.570842 465.2926 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 9.47 3741.6 - 7.61E+06 - - - 0.2972 - 1.531 0.157 - 282.2 1 2 0 0.0003 8 0 0 0 2.58E+07 1.15E+07 - - - 1.4851 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.19940.19940.2 0.62 16-Aug R.NLLGLALGR[166.11].L sp|Q8N5L8|RP25L_HUMAN 1 935.5792 1.1 24903 19940 2 935.579117 468.7969 Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1 9.75 3741.7 - 6.51E+06 - - - -0.0577 - 1.542 0.22 - 245 1 2 0 -0.0001 9 0 0 0 8.16E+07 7.41E+07 - - - 1.9188 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19941.19941.2 0.000364 16-Sep K.SLTYLSILR.N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 3 1064.623 1.25 24904 19941 2 1064.623184 533.3188 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 8.46 3741.7 - 5.72E+06 - - - 0.1766 - 1.737 0.451 - 352.4 1 2 0 0.0002 9 0 0 0 2.72E+07 2.18E+07 - - - 3.9695 1 230117_WJC_METTL3_WT_vs_EV_F03.19942.19942.3 7.12E-07 19/76 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 2.85 24905 19942 3 2197.088556 733.3694 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3741.8 - 5.70E+06 - - - 1.0468 - 3.749 0.606 - 413 1 2 0 0.0023 20 0 0 0 1.74E+07 6.10E+06 - - - 8.5016 1 230117_WJC_METTL3_WT_vs_EV_F03.19943.19943.2 0.000489 22-Dec K.LYDNLLEQNLIR.V sp|O00231|PSD11_HUMAN 1 1502.8093 1.86 24906 19943 2 1502.806887 752.4119 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3741.9 - 3.57E+06 - - - -1.601 - 2.689 0.47 - 583.3 1 2 0 -0.0024 12 0 0 0 6.15E+07 3.30E+07 - - - 5.1143 1 230117_WJC_METTL3_WT_vs_EV_F03.19944.19944.2 7.19E-06 15/28 R.LPLPSPALEYTLGSR.L sp|Q8IU81|I2BP1_HUMAN 1 1612.8825 2.91 24907 19944 2 1612.883564 807.4485 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3741.9 - 3.31E+06 - - - 0.6857 - 2.511 0.453 - 628.8 1 2 0 0.0011 15 0 0 0 8.46E+07 2.90E+07 - - - 4.65 1 230117_WJC_METTL3_WT_vs_EV_F03.19946.19946.2 2.73E-07 22-Dec K.LYDNLLEQNLIR[166.11].V sp|O00231|PSD11_HUMAN 1 1512.8176 1.86 24909 19946 2 1512.819721 757.4161 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3742.1 - 2.25E+06 - - - 1.4265 - 2.765 0.577 - 525.1 1 2 0 0.0022 12 0 0 0 6.15E+07 3.30E+07 - - - 5.9781 1 230117_WJC_METTL3_WT_vs_EV_F03.19949.19949.2 0.00668 14/24 R.ATVGILITTIASK.G "sp|Q92973|TNPO1_HUMAN,tr|A0A7P0T9C0|A0A7P0T9C0_HUMAN,tr|A0A7P0TBF0|A0A7P0TBF0_HUMAN,tr|A0A7P0T944|A0A7P0T944_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 5 1286.781 1.58 24912 19949 2 1286.778658 644.3978 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 8.8 3742.3 - 1.44E+06 - - - -1.7835 - 2.707 0.416 - 689.5 1 2 0 -0.0023 13 0 0 0 5.74E+06 3.63E+06 - - - 4.6687 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19957.19957.2 0.000965 16-Sep R.GFFGFPGPR.S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 980.4868 2 24918 19957 2 980.488282 491.2507 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3743.3 - 784478 - - - 1.4738 - 1.873 0.42 - 241.9 1 2 0 0.0014 9 0 0 0 4.31E+07 2.15E+07 - - - 3.9582 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19959.19959.2 2.81E-06 18-Oct R.LWGDIYFNPK[136.11].T sp|Q15029|U5S1_HUMAN 1 1259.643 1.44 24920 19959 2 1259.644205 630.8288 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.83 3743.6 - 813105 - - - 0.9495 - 2.052 0.363 - 306.2 1 2 0 0.0012 10 0 0 0 1.58E+07 1.10E+07 - - - 3.7282 1 230117_WJC_METTL3_WT_vs_EV_F03.19960.19960.2 0.00756 13/20 R.TLVLLDNLNVR[166.11].E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1278.7535 1.25 24921 19960 2 1278.755909 640.384 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3743.6 - 567718 - - - 1.8792 - 2.678 0.438 - 685.4 1 2 0 0.0024 11 0 0 0 7.79E+07 6.24E+07 - - - 4.9402 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19961.19961.2 0.00169 20-Oct R.VFSWGFGGYGR.L sp|Q9P258|RCC2_HUMAN 1 1231.5774 1.75 24922 19961 2 1231.579691 616.796 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 8.72 3743.7 - 557880 - - - 1.8253 - 1.861 0.397 - 305.8 1 2 0 0.0022 11 0 0 0 1.08E+07 6.16E+06 - - - 3.6528 0.997 230117_WJC_METTL3_WT_vs_EV_F03.19967.19967.2 0.159 16-Sep R.NLLGLALGR.L sp|Q8N5L8|RP25L_HUMAN 1 925.5709 1.1 24926 19967 2 925.572663 463.7927 Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1 9.75 3744.5 - 1.25E+07 - - - 1.9037 - 1.684 0.12 - 307.9 1 2 0 0.0018 9 0 0 0 8.14E+07 7.41E+07 - - - 1.4345 1 230117_WJC_METTL3_WT_vs_EV_F03.19968.19968.2 8.63E-06 18-Nov K.GIGFLTSGWR[166.11].F sp|Q8IXM3|RM41_HUMAN 1 1102.5799 1.09 24927 19968 2 1102.583934 552.2972 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 9.75 3744.6 - 8.36E+06 - - - 3.6596 - 2.265 0.478 - 454.2 1 2 0 0.004 10 0 0 0 5.09E+07 4.65E+07 - - - 4.8523 1 230117_WJC_METTL3_WT_vs_EV_F03.19969.19969.2 4.41E-05 20/30 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 8.3 24928 19969 2 1549.8843 775.9487 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3744.7 - 1.91E+06 - - - 0.973 - 3.157 0.502 - 1352.7 1 2 0 0.0015 16 0 0 0 8.41E+08 1.01E+08 - - - 5.5747 1 230117_WJC_METTL3_WT_vs_EV_F03.19971.19971.2 3.50E-09 14/20 R.PMEVFMC[160.03]SVLK.R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1339.6338 0.98 24930 19971 2 1339.634262 670.8242 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3744.9 - 1.66E+06 - - - 0.3173 - 2.63 0.616 - 784.4 1 1 0 0.0004 11 0 0 0 2.58E+07 2.64E+07 - - - 6.2066 1 230117_WJC_METTL3_WT_vs_EV_F03.19972.19972.2 7.46E-05 15/28 R.LPLPSPALEYTLGSR[166.11].L sp|Q8IU81|I2BP1_HUMAN 1 1622.8907 2.91 24931 19972 2 1622.889266 812.4526 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3745.1 - 3.80E+06 - - - -0.9009 - 2.324 0.495 - 402.1 1 2 0 -0.0015 15 0 0 0 8.46E+07 2.90E+07 - - - 4.7699 1 230117_WJC_METTL3_WT_vs_EV_F03.19973.19973.2 0.000485 13/20 R.PMEVFMC[160.03]SVLK[136.11].R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1347.648 0.98 24932 19973 2 1347.650145 674.8313 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3745.2 - 1.61E+06 - - - 1.5642 - 2.454 0.509 - 623.5 1 1 0 0.0021 11 0 0 0 2.58E+07 2.64E+07 - - - 5.2284 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.19977.19977.2 0.0515 16-Aug R.GSLITSLLR[166.11].S sp|Q53FA7|QORX_HUMAN 1 968.5894 1 24936 19977 2 968.591041 485.302 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3745.7 - 916713 - - - 1.6932 - 1.7 0.291 - 154.3 1 2 0 0.0016 9 0 0 0 8.19E+06 8.19E+06 - - - 2.7249 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.19983.19983.2 0.000762 20-Sep K.IIADIFEYTAK[136.11].H sp|P22033|MUTA_HUMAN 1 1290.6951 1.61 24942 19983 2 1290.695683 646.3548 "Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4" 4.37 3746.5 - 366866 - - - 0.4478 - 1.765 0.349 - 151.9 1 2 0 0.0006 11 0 0 0 7.39E+06 4.58E+06 - - - 3.1555 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19985.19985.3 0.0159 Sep-40 R.TLVLLDNLNVR[166.11].E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1278.7535 0.78 24944 19985 3 1278.754609 427.2584 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3746.8 - 234591 - - - 0.8626 - 2.12 0.32 - 164.1 1 2 0 0.0011 11 0 0 0 1.33E+06 1.70E+06 - - - 4.242 1 230117_WJC_METTL3_WT_vs_EV_F03.19986.19986.2 3.68E-05 22/30 R.ALIAGGGAPEIELALR[166.11].L sp|P50991|TCPD_HUMAN 1 1559.8911 8.3 24945 19986 2 1559.890103 780.9528 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3746.9 - 234584 - - - -0.6148 - 3.08 0.452 - 1924.4 1 2 0 -0.001 16 0 0 0 8.41E+08 1.01E+08 - - - 5.1449 1 230117_WJC_METTL3_WT_vs_EV_F03.19988.19988.2 3.13E-05 20-Nov K.TVLELQYVLDK[136.11].L "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1327.7479 1.1 24946 19988 2 1327.749213 664.8812 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.37 3747.1 - 5.12E+07 - - - 1.0122 - 2.232 0.468 - 294.4 1 2 0 0.0013 11 0 0 0 2.99E+08 2.71E+08 - - - 4.6693 0.9936 230117_WJC_METTL3_WT_vs_EV_F03.19992.19992.2 0.014 16-Jun R.GSLITSLLR.S sp|Q53FA7|QORX_HUMAN 1 958.5811 1 24950 19992 2 958.581744 480.2978 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3747.3 - 3.96E+06 - - - 0.6395 - 1.537 0.08 - 93 1 2 0 0.0006 9 0 0 0 8.19E+06 8.19E+06 - - - 0.8752 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19993.19993.2 0.00084 14-Sep R.YGLEC[160.03]LFR.Y "sp|Q6PKG0|LARP1_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN" 3 1056.5063 0.76 24951 19993 2 1056.507775 529.2604 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 5.99 3747.4 - 3.70E+06 - - - 1.4415 - 1.925 0.396 - 327.3 1 2 0 0.0015 8 0 0 0 1.14E+07 1.49E+07 - - - 3.9406 0.9876 230117_WJC_METTL3_WT_vs_EV_F03.19994.19994.2 4.87 16-May R.LELPADLLR.Q "sp|Q96NU1|SAM11_HUMAN,tr|A0A087WYW1|A0A087WYW1_HUMAN,tr|A0A087WX24|A0A087WX24_HUMAN,tr|A0A087X1J5|A0A087X1J5_HUMAN,tr|A0A087X223|A0A087X223_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|A0A087WXB3|A0A087WXB3_HUMAN,tr|H7C3J6|H7C3J6_HUMAN,tr|A0A087WYU3|A0A087WYU3_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 10 1038.6073 3.47 24952 19994 2 1038.608001 520.3109 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3 4.37 3747.4 - 3.26E+06 - - - 0.6307 - 1.155 0.146 - 78.4 2 2 0 0.0007 9 0 0 0 1.20E+07 3.47E+06 - - - 0.4016 0.9842 230117_WJC_METTL3_WT_vs_EV_F03.19997.19997.2 0.171 14-Jun R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 12.85 24955 19997 2 1000.556741 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3747.7 - 1.57E+06 - - - -2.5906 - 1.3 0.247 - 93.3 1 2 0 -0.0026 8 0 0 0 3.58E+07 2.79E+06 - - - 1.6558 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.19998.19998.2 0.00452 26-Dec K.IPPPVIMVQNVSFK.Y sp|Q9UG63|ABCF2_HUMAN 1 1567.8796 6.2 24956 19998 2 1567.880428 784.9471 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.75 3747.8 - 1.53E+06 - - - 0.5147 - 2.144 0.371 - 323.4 1 2 0 0.0008 14 0 0 0 7.26E+06 1.17E+06 - - - 3.6948 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.19999.19999.2 0.00519 16-Sep R.GFFGFPGPR[166.11].S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 990.4951 2.05 24957 19999 2 990.496234 496.2548 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3747.9 - 1.27E+06 - - - 1.1378 - 1.847 0.467 - 230.3 1 2 0 0.0011 9 0 0 0 4.31E+07 2.11E+07 - - - 4.265 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.20000.20000.2 0.000925 13/26 R.LEALLEAADPEVLR.R tr|D6RHC4|D6RHC4_HUMAN 1 1537.8352 2.41 24958 20000 2 1537.830864 769.9249 Ankyrin repeat and KH domain-containing protein 1 (Fragment) OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4 3748 - 1.41E+06 - - - -2.8026 - 2.433 0.434 - 522.8 1 2 0 -0.0043 14 0 0 0 4.28E+06 1.78E+06 - - - 4.4764 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.20001.20001.3 0.000118 13/52 K.IPPPVIMVQNVSFK.Y sp|Q9UG63|ABCF2_HUMAN 1 1567.8796 3.8 24959 20001 3 1567.881571 523.6338 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.75 3748.1 - 914846 - - - 1.2437 - 2.736 0.369 - 260.7 1 2 0 0.0019 14 0 0 0 4.75E+06 1.25E+06 - - - 5.3282 1 230117_WJC_METTL3_WT_vs_EV_F03.20010.20010.2 0.0286 20-Dec R.TLVLLDNLNVR.E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1268.7452 1.27 24966 20010 2 1268.747233 635.3799 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3749.1 - 2.55E+06 - - - 1.574 - 2.562 0.425 - 568.3 1 2 0 0.002 11 0 0 0 7.79E+07 6.15E+07 - - - 4.7245 1 230117_WJC_METTL3_WT_vs_EV_F03.20011.20011.3 5.28E-08 15/60 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 7.61 24967 20011 3 1549.88463 517.6349 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3749.1 - 7.58E+06 - - - 1.1859 - 2.867 0.532 - 447.1 1 2 0 0.0018 16 0 0 0 4.76E+07 6.26E+06 - - - 7.1733 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.20014.20014.2 0.014 18-Jul R.YVEFNLLYDR.G "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1330.6558 1.23 24970 20014 2 1330.66174 666.3352 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.37 3749.3 - 6.12E+06 - - - 4.5 - 1.644 0.397 - 187.2 1 2 0 0.006 10 0 0 0 2.55E+07 2.07E+07 - - - 3.359 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20015.20015.2 0.00521 18-Oct K.YFSSMAEFLK.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1221.574 1.18 24971 20015 2 1221.576176 611.7943 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 3749.4 - 1.78E+06 - - - 1.7838 - 1.655 0.423 - 213.3 1 2 0 0.0022 10 0 0 0 4.23E+07 3.57E+07 - - - 3.5709 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.20016.20016.3 0.168 14/60 R.ALIAGGGAPEIELALR[166.11].L sp|P50991|TCPD_HUMAN 1 1559.8911 8.65 24972 20016 3 1559.891784 520.971 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3749.4 - 947234 - - - 0.4629 - 1.818 0.269 - 192.7 1 2 0 0.0007 16 0 0 0 4.75E+07 5.49E+06 - - - 3.0726 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.20019.20019.2 0.00061 20-Oct K.DSLTLVFVETK[136.11].K "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1258.69 0.02 24975 20019 2 1258.689363 630.3523 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3749.7 - 681920 - - - -0.5212 - 1.74 0.412 - 360.6 1 2 0 -0.0007 11 0 0 0 1.36E+05 6.63E+06 - - - 3.5822 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.20022.20022.2 0.00147 14-Sep R.WLLSDYVK.V "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN,tr|C9JZH6|C9JZH6_HUMAN" 3 1022.5437 2.13 24978 20022 2 1022.542185 512.2791 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.83 3750.1 - 483730 - - - -1.465 - 1.631 0.256 - 257.5 1 2 0 -0.0015 8 0 0 0 1.34E+07 6.27E+06 - - - 2.4067 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20023.20023.2 0.0109 16-Sep R.VDALLLDLR.Q "sp|O75586|MED6_HUMAN,tr|G3V4A5|G3V4A5_HUMAN,tr|A0A087WYL7|A0A087WYL7_HUMAN" 3 1026.6073 6.59 24979 20023 2 1026.608745 514.3109 Mediator of RNA polymerase II transcription subunit 6 OS=Homo sapiens OX=9606 GN=MED6 PE=1 SV=2 4.21 3750.2 - 359786 - - - 1.3627 - 2.2 0.306 - 215 1 2 0 0.0014 9 0 0 0 6.65E+06 1.01E+06 - - - 3.5817 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20024.20024.2 0.00934 14-Sep K.TMLTELLR[166.11].G "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 985.5506 1.13 24980 20024 2 985.551351 493.7826 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 5.66 3750.3 - 302709 - - - 0.7894 - 1.829 0.358 - 340.1 1 2 0 0.0008 8 0 0 0 6.25E+06 5.52E+06 - - - 3.5059 1 230117_WJC_METTL3_WT_vs_EV_F03.20027.20027.2 6.94E-07 13/18 R.VFYYLVQDLK.C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1286.6911 0.9 24982 20027 2 1286.693594 644.3528 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3750.8 - 4.98E+06 - - - 1.9577 - 2.431 0.531 - 646.1 1 2 0 0.0025 10 0 0 0 9.69E+07 1.08E+08 - - - 5.4417 0.9847 230117_WJC_METTL3_WT_vs_EV_F03.20036.20036.2 1.46 14-Jul R.LLLEDLVK.K "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 941.5797 1.68 24990 20036 2 941.578757 471.7971 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 4.37 3751.7 - 1.37E+06 - - - -1.0376 - 1.235 0.165 - 99 1 2 0 -0.001 8 0 0 0 9.06E+06 5.40E+06 - - - 0.896 0.9752 230117_WJC_METTL3_WT_vs_EV_F03.20038.20038.2 0.00628 20-Jul R.YLLLLAAGDPR.E "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1200.6867 2.88 24992 20038 2 1200.681499 601.3506 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.84 3751.9 - 954909 - - - -4.2975 - 1.387 0.311 - 110.5 1 2 0 -0.0052 11 0 0 0 8.72E+06 3.03E+06 - - - 2.2214 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.20041.20041.2 0.0186 12-Jul K.LFFLQVK[136.11].E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 901.5517 0.81 24995 20041 2 901.552108 451.7831 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3752.2 - 736685 - - - 0.4803 - 1.514 0.255 - 135.3 1 2 0 0.0004 7 0 0 0 8.13E+06 1.01E+07 - - - 2.2385 0.9879 230117_WJC_METTL3_WT_vs_EV_F03.20042.20042.2 0.146 12-Jun K.LFFLQVK.E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 893.5375 0.81 24996 20042 2 893.536881 447.776 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3752.3 - 649551 - - - -0.6648 - 1.377 0.114 - 87.5 1 2 0 -0.0006 7 0 0 0 8.13E+06 1.01E+07 - - - 0.8965 0.9948 230117_WJC_METTL3_WT_vs_EV_F03.20046.20046.2 5.02E-05 16-Sep R.LTSFITVFK.Y "sp|Q13617|CUL2_HUMAN,tr|Q5T2B5|Q5T2B5_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 3 1054.6063 3.41 25000 20046 2 1054.612574 528.3104 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 8.75 3752.8 - 416930 - - - 5.9653 - 2.167 0.319 - 222.2 1 2 0 0.0063 9 0 0 0 9.96E+06 2.93E+06 - - - 3.6325 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.20050.20050.2 0.0427 12-Aug R.WIVNLIR[166.11].N "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 15 922.5628 0.9 25003 20050 2 922.562769 462.2887 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 9.75 3753.3 - 2.74E+06 - - - -0.0249 - 1.691 0.275 - 394.8 1 2 0 0 7 0 0 0 4.97E+07 5.55E+07 - - - 2.7366 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.20052.20052.2 0.00171 18-Aug R.VFYYLVQDLK[136.11].C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1294.7053 0.9 25004 20052 2 1294.706975 648.3599 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3753.5 - 4.23E+07 - - - 1.313 - 1.654 0.485 - 233 1 2 0 0.0017 10 0 0 0 9.69E+07 1.08E+08 - - - 4.0273 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.20055.20055.2 0.00892 22-Jul K.LGAIFLEGVTVK.G sp|O60942|MCE1_HUMAN 1 1245.7333 13.58 25007 20055 2 1245.737521 623.8739 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 6 3753.6 - 9.36E+06 - - - 3.4084 - 1.546 0.393 - 104.7 1 2 0 0.0042 12 0 0 0 2.02E+07 1.48E+06 - - - 3.0887 1 230117_WJC_METTL3_WT_vs_EV_F03.20058.20058.3 2.64E-10 17/72 K.LGGSLADSYLDEGFLLDKK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2040.0415 4 25010 20058 3 2040.043766 681.0211 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.23 3753.8 - 6.14E+06 - - - 1.0921 - 3.744 0.646 - 412.1 1 2 0 0.0022 19 0 0 0 9.63E+06 2.41E+06 - - - 8.985 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20059.20059.2 0.000726 18-Oct R.QEVVELLLAR[166.11].G "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1178.6898 1.22 25011 20059 2 1178.690026 590.3522 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.53 3753.9 - 4.91E+06 - - - 0.1553 - 2.057 0.383 - 413.7 1 2 0 0.0002 10 0 0 0 1.44E+07 1.18E+07 - - - 3.883 0.9799 230117_WJC_METTL3_WT_vs_EV_F03.20060.20060.2 0.839 16-Jun R.NSYLEVLLK[136.11].L sp|Q15084|PDIA6_HUMAN 1 1085.6212 1.33 25012 20060 2 1085.625161 543.8179 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 6 3753.9 - 3.31E+06 - - - 3.6385 - 1.235 0.14 - 105 1 2 0 0.0039 9 0 0 0 8.80E+06 6.63E+06 - - - 0.6844 1 230117_WJC_METTL3_WT_vs_EV_F03.20061.20061.2 4.73E-09 24-Dec R.FADALGLELAQVK.V sp|O95685|PPR3D_HUMAN 1 1373.7555 11.8 25013 20061 2 1373.75876 687.885 Protein phosphatase 1 regulatory subunit 3D OS=Homo sapiens OX=9606 GN=PPP1R3D PE=1 SV=1 4.37 3754.1 - 2.71E+06 - - - 2.3971 - 2.439 0.588 - 363.8 1 2 0 0.0033 13 0 0 0 4.99E+06 4.23E+05 - - - 5.6712 0.9744 230117_WJC_METTL3_WT_vs_EV_F03.20062.20062.2 1.78 14-Jul R.LLLEDLVK[136.11].K "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 949.5939 1.68 25014 20062 2 949.593974 475.8042 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 4.37 3754.1 - 2.68E+06 - - - 0.0421 - 1.114 0.096 - 86.6 1 2 0 0 8 0 0 0 9.06E+06 5.40E+06 - - - 0.0756 0.9844 230117_WJC_METTL3_WT_vs_EV_F03.20065.20065.2 3.66 16-May R.LELPADLLR[166.11].Q "sp|Q96NU1|SAM11_HUMAN,tr|A0A087WYW1|A0A087WYW1_HUMAN,tr|A0A087WX24|A0A087WX24_HUMAN,tr|A0A087X1J5|A0A087X1J5_HUMAN,tr|A0A087X223|A0A087X223_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|A0A087WXB3|A0A087WXB3_HUMAN,tr|H7C3J6|H7C3J6_HUMAN,tr|A0A087WYU3|A0A087WYU3_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 10 1048.6156 3.61 25017 20065 2 1048.616761 525.3151 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3 4.37 3754.4 - 2.34E+06 - - - 1.0919 - 1.097 0.146 - 56.7 3 2 0 0.0011 9 0 0 0 1.50E+07 4.16E+06 - - - 0.1737 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.20073.20073.2 0.0264 14-Aug K.AIFLFVDK[136.11].T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 959.5572 1.66 25024 20073 2 959.556496 480.7859 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3755.5 - 1.30E+06 - - - -0.6857 - 1.517 0.354 - 243.3 1 2 0 -0.0007 8 0 0 0 1.27E+07 7.67E+06 - - - 2.9123 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.20076.20076.2 0.0942 14-Jul K.AIFLFVDK.T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 951.543 1.37 25027 20076 2 951.545064 476.7788 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3755.9 - 1.29E+06 - - - 2.2175 - 1.42 0.26 - 160.9 1 2 0 0.0021 8 0 0 0 8.59E+06 6.29E+06 - - - 2.0183 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.20077.20077.3 0.0715 15/40 R.AALLELWELR[166.11]R[166.11].Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1388.8043 0.75 25028 20077 3 1388.807707 463.942 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.19 3756 - 1.22E+06 - - - 2.446 - 2.498 0.287 - 473.4 1 2 0 0.0034 11 0 0 0 1.12E+07 1.50E+07 - - - 4.3396 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20081.20081.2 0.000197 20-Sep K.LLVYEALEYAK.R "sp|Q96DB5|RMD1_HUMAN,tr|H0YB83|H0YB83_HUMAN,tr|E5RH53|E5RH53_HUMAN,tr|H0YB03|H0YB03_HUMAN" 4 1310.7122 0.14 25032 20081 2 1310.71596 656.3634 Regulator of microtubule dynamics protein 1 OS=Homo sapiens OX=9606 GN=RMDN1 PE=1 SV=1 4.53 3756.5 - 608250 - - - 2.8649 - 1.974 0.46 - 233.9 1 2 0 0.0038 11 0 0 0 2.67E+06 1.95E+07 - - - 4.2771 0.9796 230117_WJC_METTL3_WT_vs_EV_F03.20087.20087.2 0.0483 18-Jul K.EGLSFLGGLR.S "sp|Q6WKZ4|RFIP1_HUMAN,tr|E7EX40|E7EX40_HUMAN" 2 1047.5713 1.44 25038 20087 2 1047.572463 524.7929 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 6.1 3757.3 - 302238 - - - 1.115 - 1.292 0.061 - 103.6 3 2 0 0.0012 10 0 0 0 1.80E+06 1.25E+06 - - - -0.0068 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.20097.20097.2 0.00431 18/22 R.ALLANALTSALR[166.11].L "sp|P57088|TMM33_HUMAN,tr|D6RAA6|D6RAA6_HUMAN" 2 1222.7273 -1 25047 20097 2 1222.732664 612.3709 Transmembrane protein 33 OS=Homo sapiens OX=9606 GN=TMEM33 PE=1 SV=2 9.79 3758.4 - 2.48E+06 - - - 4.3943 - 2.617 0.305 - 1676.3 1 2 0 0.0054 12 0 0 0 0.00E+00 0.00E+00 - - - 3.8233 0.9856 230117_WJC_METTL3_WT_vs_EV_F03.20098.20098.2 0.984 12-Aug R.IIWELIK.E "sp|O75874|IDHC_HUMAN,tr|C9JLU6|C9JLU6_HUMAN,tr|C9J4N6|C9J4N6_HUMAN,tr|C9JJE5|C9JJE5_HUMAN" 4 913.5637 8.33 25048 20098 2 913.567403 457.7891 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 6 3758.6 - 1.51E+06 - - - 4.0643 - 1.522 0.106 - 159.8 1 2 0 0.0037 7 0 0 0 3.22E+07 3.87E+06 - - - 1.1536 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20099.20099.2 0.00122 18-Nov R.FC[160.03]IWTESAFR[166.11].K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1325.6102 -1 25049 20099 2 1325.614383 663.8124 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3758.6 - 1.45E+06 - - - 3.1457 - 2.253 0.395 - 478.2 1 2 0 0.0042 10 0 0 0 0.00E+00 0.00E+00 - - - 4.2244 0.9947 230117_WJC_METTL3_WT_vs_EV_F03.20100.20100.2 0.337 12-Jul R.IIWQFIK.E "sp|P48735|IDHP_HUMAN,tr|H0YL11|H0YL11_HUMAN" 2 946.564 -1 25050 20100 2 946.568106 474.2893 "Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2" 8.75 3758.8 - 1.39E+06 - - - 4.3124 - 1.254 0.327 - 126.1 1 2 0 0.0041 7 0 0 0 0.00E+00 0.00E+00 - - - 2.1721 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.20101.20101.2 0.0193 18-Oct R.FC[160.03]IWTESAFR.K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1315.6019 1.02 25051 20101 2 1315.607598 658.8082 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3758.9 - 1.11E+06 - - - 4.2984 - 2.081 0.384 - 424 1 2 0 0.0057 10 0 0 0 7.45E+06 7.30E+06 - - - 3.9211 1 230117_WJC_METTL3_WT_vs_EV_F03.20102.20102.2 3.85E-09 17/28 L.LVSVSALTLATETVR.S sp|P50991|TCPD_HUMAN 1 1558.893 56.28 25052 20102 2 1558.899012 780.4538 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6 3759 - 1.06E+06 - - - 3.8418 - 3.067 0.605 - 1182.1 1 1 0 0.006 15 0 0 0 7.27E+07 1.29E+06 - - - 6.2629 1 230117_WJC_METTL3_WT_vs_EV_F03.20103.20103.2 0.000415 13/20 R.AFITNIPFDVK[136.11].W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1271.7005 2.56 25053 20103 2 1271.705872 636.8575 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3759.1 - 970271 - - - 4.2054 - 2.244 0.491 - 599.1 1 2 0 0.0053 11 0 0 0 4.75E+08 1.86E+08 - - - 4.8524 0.967 230117_WJC_METTL3_WT_vs_EV_F03.20105.20105.2 1.74 14-Jul -.MLPLSLLK[136.11].T "sp|Q9Y4Z0|LSM4_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 921.5813 7.59 25055 20105 2 921.58196 461.7979 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 8.5 3759.4 - 703323 - - - 0.7585 - 1.256 0.028 - 93.7 3 2 0 0.0007 8 0 0 0 2.94E+07 3.87E+06 - - - -0.2781 0.8561 230117_WJC_METTL3_WT_vs_EV_F03.20108.20108.2 0.467 18-Sep R.FSDFLGLYEK.L sp|Q13596|SNX1_HUMAN 1 1217.5968 3.16 25058 20108 2 1217.603537 609.8057 Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3 4.37 3759.8 - 611864 - - - 5.4994 - 0.917 0.179 - 131.1 1 2 0 0.0067 10 0 0 0 3.08E+06 9.75E+05 - - - 0.1191 0.9825 230117_WJC_METTL3_WT_vs_EV_F03.20109.20109.2 1.92 12-Jul R.TLLEFLK[136.11].R "sp|Q14232|EI2BA_HUMAN,tr|F5H0D0|F5H0D0_HUMAN,tr|H0YGG4|H0YGG4_HUMAN" 3 870.5306 -1 25059 20109 2 870.533885 436.2726 Translation initiation factor eIF-2B subunit alpha OS=Homo sapiens OX=9606 GN=EIF2B1 PE=1 SV=1 5.66 3759.9 - 584926 - - - 3.7678 - 1.312 0.129 - 153.5 1 2 0 0.0033 7 0 0 0 0.00E+00 0.00E+00 - - - 0.8532 1 230117_WJC_METTL3_WT_vs_EV_F03.20110.20110.2 2.61E-06 22-Nov K.FLQDTIEEMALK[136.11].N sp|O95202|LETM1_HUMAN 1 1444.7363 -1 25060 20110 2 1444.741472 723.3754 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.14 3760 - 584713 - - - 3.5674 - 2.461 0.496 - 311.4 1 2 0 0.0052 12 0 0 0 0.00E+00 0.00E+00 - - - 5.0724 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20112.20112.3 0.00782 Aug-40 K.NAAIAVLEELK.K "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1169.6656 -1 25062 20112 3 1169.669439 390.8958 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.53 3760.3 - 323785 - - - 3.2915 - 1.681 0.38 - 67 1 2 0 0.0039 11 0 0 0 0.00E+00 0.00E+00 - - - 4.2511 0.9822 230117_WJC_METTL3_WT_vs_EV_F03.20116.20116.2 2.34E-05 15/24 R.ALDPAAAAYLFQR.Q "sp|O75376|NCOR1_HUMAN,tr|E7EVK1|E7EVK1_HUMAN" 2 1405.7354 -1 25065 20116 2 1405.747567 703.875 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 5.88 3760.8 - 687573 - - - 8.6553 - 3.176 0.246 - 1162.7 1 2 0 0.0122 13 0 0 0 0.00E+00 0.00E+00 - - - 3.8201 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.20117.20117.2 0.009 18-Oct R.DLASVQALLR[166.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1094.6323 0.85 25066 20117 2 1094.636574 548.3234 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3760.9 - 4.96E+06 - - - 3.8789 - 2.212 0.328 - 334.8 1 2 0 0.0042 10 0 0 0 1.83E+07 2.14E+07 - - - 3.6783 1 230117_WJC_METTL3_WT_vs_EV_F03.20118.20118.2 1.16E-07 18/26 K.LLTGELLPTDGMIR.K sp|Q9UG63|ABCF2_HUMAN 1 1527.8331 2.14 25067 20118 2 1527.83714 764.9238 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.37 3761 - 3.43E+06 - - - 2.6672 - 3.05 0.531 - 910.6 1 2 0 0.0041 14 0 0 0 1.07E+07 5.01E+06 - - - 5.7601 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.20119.20119.2 0.0671 14-Oct K.QDILTIFK.R "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV8|B0QYV8_HUMAN" 2 976.5593 1.59 25068 20119 2 976.562625 489.2869 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3761 - 2.82E+06 - - - 3.371 - 2.019 0.387 - 284.9 1 2 0 0.0033 8 0 0 0 1.42E+07 8.91E+06 - - - 4.0174 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.20120.20120.2 0.0163 14-Aug K.EILIPVFK.N sp|P53396|ACLY_HUMAN 1 957.5899 1.33 25069 20120 2 957.59327 479.8022 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3761.1 - 2.11E+06 - - - 3.514 - 1.492 0.305 - 211 1 2 0 0.0034 8 0 0 0 2.23E+07 1.67E+07 - - - 2.4994 0.998 230117_WJC_METTL3_WT_vs_EV_F03.20121.20121.2 0.0141 14-Oct K.QDILTIFK[136.11].R "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV8|B0QYV8_HUMAN" 2 984.5735 1.59 25070 20121 2 984.577837 493.294 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3761.2 - 2.02E+06 - - - 4.3714 - 1.965 0.321 - 313.9 1 2 0 0.0043 8 0 0 0 1.41E+07 8.91E+06 - - - 3.4478 1 230117_WJC_METTL3_WT_vs_EV_F03.20122.20122.2 0.000815 15/26 K.ALLAVIGADSVTLK.N sp|Q9NYH9|UTP6_HUMAN 1 1369.8181 -1 25071 20122 2 1369.821638 685.9163 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3761.4 - 1.77E+06 - - - 2.6069 - 2.906 0.407 - 923.5 1 2 0 0.0036 14 0 0 0 0.00E+00 0.00E+00 - - - 4.723 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.20124.20124.2 0.00895 14-Aug K.EILIPVFK[136.11].N sp|P53396|ACLY_HUMAN 1 965.6041 1.34 25073 20124 2 965.607431 483.8093 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3761.6 - 1.69E+06 - - - 3.4445 - 1.553 0.403 - 217.9 1 2 0 0.0033 8 0 0 0 2.22E+07 1.66E+07 - - - 3.3441 1 230117_WJC_METTL3_WT_vs_EV_F03.20125.20125.2 1.31E-06 20-Dec R.FSYLAVIEGAK[136.11].F "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 1204.6583 -1 25074 20125 2 1204.66157 603.3364 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 6 3761.7 - 1.48E+06 - - - 2.6937 - 2.271 0.586 - 409.2 1 2 0 0.0032 11 0 0 0 0.00E+00 0.00E+00 - - - 5.5871 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20126.20126.2 0.0055 26-Dec K.ALLAVIGADSVTLK[136.11].N sp|Q9NYH9|UTP6_HUMAN 1 1377.8323 -1 25075 20126 2 1377.835725 689.9234 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3761.8 - 1.41E+06 - - - 2.5097 - 2.483 0.323 - 487.7 1 2 0 0.0035 14 0 0 0 0.00E+00 0.00E+00 - - - 3.7079 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.20127.20127.2 0.000528 20-Nov R.ELGLGLGLGLK[136.11].E "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 1076.6685 1.03 25076 20127 2 1076.671716 539.3415 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 6.1 3761.9 - 1.38E+06 - - - 2.9907 - 1.795 0.417 - 325.1 1 2 0 0.0032 11 0 0 0 8.61E+06 8.35E+06 - - - 3.7025 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.20129.20129.2 0.0284 20-Sep R.VLPSIVNEVLK[136.11].S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1217.7475 1.31 25078 20129 2 1217.751148 609.881 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3762.1 - 1.63E+06 - - - 3.0162 - 1.329 0.293 - 172.9 1 2 0 0.0037 11 0 0 0 7.80E+07 5.97E+07 - - - 1.9734 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.20136.20136.2 0.0434 20-Sep R.AFITNIPFDVK.W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1263.6863 2.56 25084 20136 2 1263.690901 632.8504 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3763 - 9.99E+07 - - - 3.6219 - 1.662 0.391 - 306.7 1 2 0 0.0046 11 0 0 0 4.75E+08 1.86E+08 - - - 3.3018 1 230117_WJC_METTL3_WT_vs_EV_F03.20140.20140.2 0.000224 13/24 K.ILTFDQLALDSPK[136.11].G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1467.8064 0.76 25088 20140 2 1467.807236 734.9105 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3763.2 - 3.59E+06 - - - 0.5382 - 2.681 0.511 - 560.8 1 2 0 0.0008 13 0 0 0 1.13E+08 1.49E+08 - - - 5.3461 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20141.20141.2 0.000184 20-Nov R.ELGLGLGLGLK.E "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 1068.6543 1.03 25089 20141 2 1068.657673 535.3344 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 6.1 3763.3 - 3.50E+06 - - - 3.16 - 2.07 0.454 - 351.6 1 2 0 0.0034 11 0 0 0 8.61E+06 8.35E+06 - - - 4.3614 1 230117_WJC_METTL3_WT_vs_EV_F03.20144.20144.2 5.92E-05 15/24 K.ILTFDQLALDSPK.G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1459.7922 0.76 25092 20144 2 1459.794712 730.9034 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3763.5 - 2.41E+06 - - - 1.6893 - 2.834 0.553 - 751.5 1 2 0 0.0025 13 0 0 0 1.13E+08 1.49E+08 - - - 5.7982 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.20145.20145.2 0.0103 20-Oct R.VLPSIVNEVLK.S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1209.7333 1.38 25093 20145 2 1209.738194 605.8739 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3763.5 - 2.36E+06 - - - 4.0662 - 1.777 0.417 - 318.4 1 2 0 0.0049 11 0 0 0 1.76E+08 1.28E+08 - - - 3.6747 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.20146.20146.2 0.0221 16-Oct R.ALQLLYDLR.Y "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1103.6339 0.84 25094 20146 2 1103.637061 552.8242 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.88 3763.6 - 2.17E+06 - - - 2.8687 - 2.121 0.277 - 488.5 1 2 0 0.0032 9 0 0 0 5.15E+06 6.15E+06 - - - 3.2612 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20147.20147.2 0.465 18-Oct K.LGLFPSNFVK.E sp|Q9Y5K6|CD2AP_HUMAN 1 1120.6281 1.41 25095 20147 2 1120.629598 561.3213 CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1 8.75 3763.7 - 1.74E+06 - - - 1.3537 - 1.894 0.325 - 244 1 2 0 0.0015 10 0 0 0 3.78E+06 2.67E+06 - - - 3.2238 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20148.20148.2 2.29E-05 16-Aug R.DGFVC[160.03]ALLR.F "sp|Q8WUY1|THEM6_HUMAN,tr|H0YAR9|H0YAR9_HUMAN" 2 1049.5328 -1 25096 20148 2 1049.531494 525.7737 Protein THEM6 OS=Homo sapiens OX=9606 GN=THEM6 PE=1 SV=2 5.83 3763.8 - 1.50E+06 - - - -1.2453 - 1.655 0.498 - 197 1 2 0 -0.0013 9 0 0 0 0.00E+00 0.00E+00 - - - 4.1763 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.20149.20149.3 4.41E-06 13/44 R.LLHLPLSLTALK.L sp|Q9BTT6|LRRC1_HUMAN 1 1317.8384 3.2 25097 20149 3 1317.839945 440.2867 Leucine-rich repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRRC1 PE=1 SV=1 8.76 3763.9 - 1.44E+06 - - - 1.1663 - 2.346 0.426 - 334.7 1 2 0 0.0015 12 0 0 0 3.42E+06 1.07E+06 - - - 5.6526 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.20151.20151.2 0.161 20-Nov R.LLGDLLPEAVR[166.11].F sp|Q9H1B7|I2BPL_HUMAN 1 1204.7055 7.87 25099 20151 2 1204.708028 603.36 Probable E3 ubiquitin-protein ligase IRF2BPL OS=Homo sapiens OX=9606 GN=IRF2BPL PE=1 SV=1 4.37 3764.1 - 1.15E+06 - - - 2.1042 - 2.22 0.224 - 298.7 1 2 0 0.0025 11 0 0 0 2.74E+07 3.49E+06 - - - 2.8521 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.20152.20152.2 0.0131 12-Aug R.YGLVFFR.Q "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN,tr|F6WRY4|F6WRY4_HUMAN" 4 900.4858 1.38 25100 20152 2 900.486503 451.2502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.75 3764.2 - 1.14E+06 - - - 0.8096 - 1.772 0.248 - 258.4 1 2 0 0.0007 7 0 0 0 2.48E+06 1.80E+06 - - - 2.6853 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.20154.20154.2 0.0506 20-Aug R.LLTGWMPTAIR.G "sp|Q12769|NU160_HUMAN,tr|E9PR16|E9PR16_HUMAN,tr|G3V198|G3V198_HUMAN" 3 1257.6904 0.63 25102 20154 2 1257.694132 629.8525 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 9.75 3764.4 - 920951 - - - 2.996 - 1.505 0.336 - 231.6 1 2 0 0.0038 11 0 0 0 9.84E+06 1.55E+07 - - - 2.6274 1 230117_WJC_METTL3_WT_vs_EV_F03.20155.20155.2 4.35E-08 24-Dec R.PVGTSLFLQTALR.G sp|Q9H9S5|FKRP_HUMAN 1 1401.798 -1 25103 20155 2 1401.800292 701.9063 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 10.18 3764.5 - 768631 - - - 1.635 - 2.642 0.606 - 458.4 1 1 0 0.0023 13 0 0 0 0.00E+00 0.00E+00 - - - 6.0097 1 230117_WJC_METTL3_WT_vs_EV_F03.20158.20158.2 7.98E-07 14/22 K.MFIGGLSWDTTK[136.11].K "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 1362.6733 1.16 25105 20158 2 1362.673331 682.3439 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 5.59 3764.9 - 1.44E+06 - - - 0.0059 - 2.36 0.579 - 519.3 1 2 0 0 12 0 0 0 1.70E+07 1.47E+07 - - - 5.5768 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.20161.20161.2 0.656 18-Jul R.LFALVLTPTR.E sp|Q9H0S4|DDX47_HUMAN 1 1129.6859 1.06 25108 20161 2 1129.690643 565.8502 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 9.75 3765.3 - 709632 - - - 4.172 - 1.837 0.312 - 128 3 2 0 0.0047 10 0 0 0 6.28E+06 5.90E+06 - - - 2.8283 0.8838 230117_WJC_METTL3_WT_vs_EV_F03.20162.20162.2 0.00801 16-Jul R.LFPLIQTMH.S "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 9 1098.5896 - 25109 20162 2 1098.593593 550.3021 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.74 3765.4 - 368880 - - - 3.6465 - 1.538 0.365 - 165.9 1 1 0 0.004 9 0 0 0 - - - - - 2.981 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.20163.20163.2 0.00584 12-Jun R.YGLVFFR[166.11].Q "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN,tr|F6WRY4|F6WRY4_HUMAN" 4 910.494 -1 25110 20163 2 910.495874 456.2543 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.75 3765.5 - 335162 - - - 2.0099 - 1.529 0.149 - 137.6 1 2 0 0.0018 7 0 0 0 0.00E+00 0.00E+00 - - - 1.4864 0.9821 230117_WJC_METTL3_WT_vs_EV_F03.20166.20166.2 6.68 22-Jun K.SFSTALYGESDL.- "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|H0YJW3|H0YJW3_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|H7C144|H7C144_HUMAN" 14 1288.5823 - 25113 20166 2 1288.581753 645.2984 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 3.67 3765.9 - 242762 - - - -0.4346 - 1.147 0.15 - 71.6 1 2 0 -0.0006 12 0 0 0 - - - - - 0.5096 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20168.20168.2 0.000135 28-Sep K.ELVGPPLAETVFTPK.T sp|P49792|RBP2_HUMAN 1 1596.8763 2.18 25115 20168 2 1596.879514 799.4454 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3766.2 - 210902 - - - 2.0064 - 1.693 0.44 - 185.5 1 2 0 0.0032 15 0 0 0 8.28E+06 3.80E+06 - - - 3.5843 0.9931 230117_WJC_METTL3_WT_vs_EV_F03.20169.20169.3 0.394 Sep-44 R.LLHLPLSLTALK[136.11].L sp|Q9BTT6|LRRC1_HUMAN 1 1325.8526 3.2 25116 20169 3 1325.855811 442.9581 Leucine-rich repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRRC1 PE=1 SV=1 8.76 3766.3 - 196717 - - - 2.4158 - 1.096 0.278 - 43.2 1 2 0 0.0032 12 0 0 0 3.42E+06 1.07E+06 - - - 1.8926 0.9832 230117_WJC_METTL3_WT_vs_EV_F03.20172.20172.2 0.335 12-Jun R.WFVFDAR.R sp|Q9UPU7|TBD2B_HUMAN 1 939.4603 -1 25119 20172 2 939.462901 470.7374 TBC1 domain family member 2B OS=Homo sapiens OX=9606 GN=TBC1D2B PE=1 SV=2 5.84 3766.7 - 100937 - - - 2.7824 - 1.094 0.151 - 77.3 1 2 0 0.0026 7 0 0 0 0.00E+00 0.00E+00 - - - 0.4401 0.998 230117_WJC_METTL3_WT_vs_EV_F03.20180.20180.2 0.0146 14-Jul R.LLLTPWVK[136.11].F sp|Q14152|EIF3A_HUMAN 1 976.6201 0.96 25126 20180 2 976.621256 489.3173 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.75 3767.7 - 982184 - - - 1.1949 - 1.621 0.167 - 139 1 2 0 0.0012 8 0 0 0 1.09E+07 1.13E+07 - - - 1.7309 0.9601 230117_WJC_METTL3_WT_vs_EV_F03.20187.20187.2 0.00654 22-Jul K.AAAIGIDLGTTY.S "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1164.6027 - 25131 20187 2 1164.60473 583.3086 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 3.8 3768.4 - 1.30E+06 - - - 1.7826 - 1.614 0.396 - 174.7 1 1 0 0.0021 12 0 0 0 - - - - - 3.2248 1 230117_WJC_METTL3_WT_vs_EV_F03.20188.20188.2 0.00575 15/20 R.IPDQLVILDMK.H "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1283.7159 1.42 25132 20188 2 1283.717446 642.8652 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.21 3768.5 - 303100 - - - 1.1965 - 3.004 0.496 - 989.2 1 2 0 0.0015 11 0 0 0 4.25E+07 2.99E+07 - - - 5.6796 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20190.20190.2 0.0372 16-Oct K.LGFMSAFVK[136.11].A "sp|P36957|ODO2_HUMAN,tr|Q86SW4|Q86SW4_HUMAN" 2 1006.5401 0.95 25134 20190 2 1006.542054 504.2773 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 8.75 3768.7 - 308763 - - - 1.9175 - 1.854 0.234 - 239.7 1 2 0 0.0019 9 0 0 0 3.55E+06 3.75E+06 - - - 2.5547 0.999 230117_WJC_METTL3_WT_vs_EV_F03.20192.20192.2 4.70E-05 14-Aug R.DWVLNEFR[166.11].S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1087.5326 1.33 25136 20192 2 1087.535644 544.7736 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3768.9 - 261035 - - - 2.7861 - 1.801 0.29 - 376 1 2 0 0.003 8 0 0 0 3.46E+07 2.60E+07 - - - 2.9564 1 230117_WJC_METTL3_WT_vs_EV_F03.20194.20194.2 0.000579 16/20 R.IPDQLVILDMK[136.11].H "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1291.7301 1.42 25138 20194 2 1291.732533 646.8723 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.21 3769.1 - 211957 - - - 1.8758 - 3.086 0.484 - 1136.5 1 2 0 0.0024 11 0 0 0 4.25E+07 2.99E+07 - - - 5.6635 0.9961 230117_WJC_METTL3_WT_vs_EV_F03.20197.20197.2 4.69E-05 16-Oct K.MTILQTYFR.Q sp|O75348|VATG1_HUMAN 1 1171.606 0.71 25141 20197 2 1171.612619 586.8103 V-type proton ATPase subunit G 1 OS=Homo sapiens OX=9606 GN=ATP6V1G1 PE=1 SV=3 8.5 3769.4 - 135393 - - - 5.6794 - 2.041 0.361 - 391.8 1 2 0 0.0067 9 0 0 0 5.50E+06 7.79E+06 - - - 3.7693 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.20198.20198.2 0.000306 16-Sep K.MTILQTYFR[166.11].Q sp|O75348|VATG1_HUMAN 1 1181.6142 0.75 25142 20198 2 1181.619623 591.8144 V-type proton ATPase subunit G 1 OS=Homo sapiens OX=9606 GN=ATP6V1G1 PE=1 SV=3 8.5 3769.5 - 133276 - - - 4.5599 - 2.153 0.367 - 271 1 2 0 0.0054 9 0 0 0 6.42E+06 8.56E+06 - - - 3.9685 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.20210.20210.2 1.11 16-Aug K.LGFMSAFVK.A "sp|P36957|ODO2_HUMAN,tr|Q86SW4|Q86SW4_HUMAN" 2 998.5259 0.95 25152 20210 2 998.52787 500.2702 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 8.75 3770.7 - 196121 - - - 1.9489 - 1.247 0.252 - 131.3 1 2 0 0.0019 9 0 0 0 3.55E+06 3.75E+06 - - - 1.5403 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.20211.20211.3 0.00048 Oct-40 K.LLPQFLLHLDK[136.11].L "sp|Q8N4J0|CARME_HUMAN,tr|Q5T8V1|Q5T8V1_HUMAN,tr|Q5T8U9|Q5T8U9_HUMAN" 3 1343.8057 1.42 25153 20211 3 1343.810652 448.9425 Carnosine N-methyltransferase OS=Homo sapiens OX=9606 GN=CARNMT1 PE=1 SV=1 6.74 3770.8 - 68832.7 - - - 3.7163 - 1.969 0.465 - 149.5 1 2 0 0.005 11 0 0 0 2.81E+06 1.98E+06 - - - 5.6476 0.996 230117_WJC_METTL3_WT_vs_EV_F03.20215.20215.2 0.00089 24-Nov R.LAALPNVYEVISK[136.11].S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1423.8166 2.77 25157 20215 2 1423.825032 712.9156 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3771.2 - 0 - - - 5.9102 - 2.03 0.435 - 321.6 1 2 0 0.0084 13 0 0 0 1.18E+07 4.27E+06 - - - 4.0685 1 230117_WJC_METTL3_WT_vs_EV_F03.20219.20219.2 3.79E-11 17/36 R.YEGILYTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2100.0627 1.06 25161 20219 2 2100.067353 1051.0386 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3771.8 - 0 - - - 2.2314 - 3.362 0.652 - 739.7 1 2 0 0.0047 19 0 0 0 1.93E+06 1.82E+06 - - - 6.8363 0.9949 230117_WJC_METTL3_WT_vs_EV_F03.20222.20222.2 0.00694 12-Aug R.FVFLLDR.G sp|Q13045|FLII_HUMAN 1 908.512 1.87 25162 20222 2 908.513095 455.2633 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3772.2 - 1.01E+06 - - - 1.2174 - 1.579 0.063 - 248.5 1 2 0 0.0011 7 0 0 0 1.45E+07 7.75E+06 - - - 0.9533 0.9969 230117_WJC_METTL3_WT_vs_EV_F03.20231.20231.2 0.000937 13/24 R.LAALPNVYEVISK.S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1415.8024 2.77 25171 20231 2 1415.808477 708.9085 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3773.1 - 312310 - - - 4.2803 - 2.305 0.212 - 441.8 1 2 0 0.0061 13 0 0 0 1.18E+07 4.27E+06 - - - 2.7482 1 230117_WJC_METTL3_WT_vs_EV_F03.20233.20233.2 2.68E-06 16/28 K.ELVGPPLAETVFTPK[136.11].T sp|P49792|RBP2_HUMAN 1 1604.8905 2.66 25173 20233 2 1604.893285 803.4525 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3773.3 - 251654 - - - 1.7291 - 2.425 0.558 - 673.4 1 2 0 0.0028 15 0 0 0 1.09E+07 4.11E+06 - - - 5.3394 1 230117_WJC_METTL3_WT_vs_EV_F03.20235.20235.2 1.82E-13 19/36 R.YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2108.0769 1.06 25175 20235 2 2108.083512 1055.0457 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3773.6 - 156831 - - - 3.1522 - 3.789 0.723 - 1068.4 1 2 0 0.0066 19 0 0 0 1.93E+06 1.82E+06 - - - 7.654 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.20239.20239.2 0.00269 14-Aug K.VNLAELFK[136.11].G sp|P30044|PRDX5_HUMAN 1 940.5473 2.59 25177 20239 2 940.551404 471.2809 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.97 3774.2 - 5.04E+06 - - - 4.3443 - 1.86 0.346 - 202.8 1 2 0 0.0041 8 0 0 0 1.36E+08 5.25E+07 - - - 3.4669 0.9954 230117_WJC_METTL3_WT_vs_EV_F03.20240.20240.3 0.0249 Nov-48 R.WLPLGLGLNHLGK.G "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1416.8242 1.94 25178 20240 3 1416.830289 473.282 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 8.76 3774.2 - 1.27E+06 - - - 4.3294 - 1.97 0.243 - 137.8 1 2 0 0.0061 13 0 0 0 4.58E+06 2.36E+06 - - - 3.0859 0.991 230117_WJC_METTL3_WT_vs_EV_F03.20241.20241.2 0.104 12-Jun R.FVFLLDR[166.11].G sp|Q13045|FLII_HUMAN 1 918.5203 1.75 25179 20241 2 918.52074 460.2674 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3774.3 - 2.87E+06 - - - 0.5237 - 1.295 0.107 - 153.9 1 2 0 0.0005 7 0 0 0 1.31E+07 7.46E+06 - - - 0.6503 1 230117_WJC_METTL3_WT_vs_EV_F03.20242.20242.2 6.21E-05 14/26 K.LLAESVTEVEIFGK.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1533.829 1.48 25180 20242 2 1533.832007 767.9218 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 3774.4 - 1.74E+06 - - - 1.9435 - 2.823 0.497 - 581.7 1 2 0 0.003 14 0 0 0 1.14E+07 7.72E+06 - - - 5.3152 0.9922 230117_WJC_METTL3_WT_vs_EV_F03.20243.20243.2 0.0913 12-Jun K.YLFTLIR.A sp|P57740|NU107_HUMAN 1 924.5433 0.62 25181 20243 2 924.546262 463.2789 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 8.75 3774.4 - 1.48E+06 - - - 3.2156 - 1.224 0.205 - 145.2 1 2 0 0.003 7 0 0 0 3.75E+06 6.06E+06 - - - 1.1946 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.20244.20244.2 0.00548 14-Aug R.LFSWLVNR.L "sp|O43795|MYO1B_HUMAN,sp|Q8WXR4|MYO3B_HUMAN,tr|F5H2J1|F5H2J1_HUMAN,tr|A0A0U1RRI3|A0A0U1RRI3_HUMAN,tr|E9PDF6|E9PDF6_HUMAN" 5 1033.5709 1 25182 20244 2 1033.57273 517.7927 Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3 9.75 3774.5 - 1.35E+06 - - - 1.7696 - 1.615 0.322 - 194.1 1 2 0 0.0018 8 0 0 0 3.42E+06 3.43E+06 - - - 2.8644 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20245.20245.2 0.00188 16-Sep R.DSVVLSLLK.Q sp|O43264|ZW10_HUMAN 1 972.5855 1.12 25183 20245 2 972.584568 487.3001 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 5.84 3774.6 - 1.25E+06 - - - -1.0076 - 1.751 0.455 - 288.9 1 2 0 -0.001 9 0 0 0 4.10E+06 3.66E+06 - - - 4.022 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20246.20246.2 0.00357 18-Oct R.GLAVFISDIR[166.11].N "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|M0R2D9|M0R2D9_HUMAN,tr|E9PR62|E9PR62_HUMAN" 4 1099.6265 1.42 25184 20246 2 1099.626359 550.8205 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 5.84 3774.6 - 1.23E+06 - - - -0.1419 - 2.13 0.405 - 478.2 1 2 0 -0.0002 10 0 0 0 9.57E+06 6.75E+06 - - - 4.1428 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20247.20247.2 0.000859 16-Sep K.QVDLIDLVR.W sp|Q9UKN8|TF3C4_HUMAN 1 1069.6132 1.28 25185 20247 2 1069.614992 535.8139 General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2 4.21 3774.7 - 1.19E+06 - - - 1.7137 - 1.883 0.401 - 280.9 1 2 0 0.0018 9 0 0 0 4.84E+06 3.79E+06 - - - 3.8331 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.20249.20249.2 0.00698 14-Aug R.LFSWLVNR[166.11].L "sp|O43795|MYO1B_HUMAN,sp|Q8WXR4|MYO3B_HUMAN,tr|F5H2J1|F5H2J1_HUMAN,tr|A0A0U1RRI3|A0A0U1RRI3_HUMAN,tr|E9PDF6|E9PDF6_HUMAN" 5 1043.5792 0.99 25187 20249 2 1043.578345 522.7969 Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3 9.75 3774.9 - 1.01E+06 - - - -0.7915 - 1.675 0.332 - 201.7 1 2 0 -0.0008 8 0 0 0 3.42E+06 3.47E+06 - - - 3.0486 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.20250.20250.2 0.285 18-Jul K.NGFLLDGFPR.T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1134.5822 3.16 25188 20250 2 1134.583973 568.2984 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3774.9 - 809959 - - - 1.568 - 1.376 0.228 - 149.1 1 2 0 0.0018 10 0 0 0 4.65E+06 1.47E+06 - - - 1.6154 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.20257.20257.3 1.59E-05 13/72 R.YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2108.0769 1.01 25195 20257 3 2108.081726 703.6996 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3775.7 - 485409 - - - 2.3049 - 2.488 0.412 - 186.1 1 2 0 0.0049 19 0 0 0 1.41E+06 1.39E+06 - - - 5.3714 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.20258.20258.2 9.12E-05 22-Oct R.DLAQDEAVWLER.G "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1443.6994 0.99 25196 20258 2 1443.694866 722.857 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 3.92 3775.9 - 412156 - - - -3.1461 - 2.31 0.388 - 402.6 1 2 0 -0.0045 12 0 0 0 1.35E+06 1.36E+06 - - - 4.1083 1 230117_WJC_METTL3_WT_vs_EV_F03.20260.20260.2 0.00019 22-Nov R.DLAQDEAVWLER[166.11].G "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1453.7077 0.99 25197 20260 2 1453.711967 727.8611 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 3.92 3776.3 - 162539 - - - 2.9504 - 2.196 0.487 - 471.3 1 2 0 0.0043 12 0 0 0 1.35E+06 1.36E+06 - - - 4.7064 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.20262.20262.2 0.000537 18-Dec K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.59 25199 20262 2 1168.712351 585.3606 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3776.5 - 3.88E+06 - - - 4.8139 - 2.389 0.378 - 421 1 2 0 0.0056 10 0 0 0 5.92E+09 3.72E+09 - - - 4.262 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.20263.20263.2 0.0173 18-Nov K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.59 25200 20263 2 1176.726623 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3776.6 - 3.31E+06 - - - 4.8423 - 2.247 0.287 - 310.2 1 2 0 0.0057 10 0 0 0 5.92E+09 3.72E+09 - - - 3.4188 1 230117_WJC_METTL3_WT_vs_EV_F03.20265.20265.2 7.83E-07 17/26 K.LLAESVTEVEIFGK[136.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1541.8432 1.48 25202 20265 2 1541.849252 771.9289 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 3776.9 - 1.25E+06 - - - 3.9083 - 3.122 0.552 - 882.7 1 2 0 0.006 14 0 0 0 1.14E+07 7.72E+06 - - - 5.9731 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.20266.20266.2 0.00196 18-Oct R.VDILDPALLR.S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1123.6601 2.11 25203 20266 2 1123.665869 562.8373 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3777 - 1.02E+06 - - - 5.1252 - 2.275 0.382 - 324.4 1 2 0 0.0058 10 0 0 0 1.59E+08 7.54E+07 - - - 4.155 0.9821 230117_WJC_METTL3_WT_vs_EV_F03.20267.20267.2 0.00182 16-Aug R.DSVVLSLLK[136.11].Q sp|O43264|ZW10_HUMAN 1 980.5997 1.14 25204 20267 2 980.604347 491.3072 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 5.84 3777.2 - 622245 - - - 4.69 - 1.631 0.117 - 150.4 1 2 0 0.0046 9 0 0 0 4.16E+06 3.66E+06 - - - 1.319 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.20268.20268.2 0.0821 18-Dec R.VDILDPALLR[166.11].S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1133.6684 2.11 25205 20268 2 1133.672906 567.8415 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3777.3 - 563717 - - - 3.9923 - 2.231 0.307 - 416.6 1 2 0 0.0045 10 0 0 0 1.59E+08 7.54E+07 - - - 3.547 0.9913 230117_WJC_METTL3_WT_vs_EV_F03.20269.20269.2 0.569 16-Jul K.FPEILATLR.G sp|P54198|HIRA_HUMAN 1 1058.6124 2.64 25206 20269 2 1058.614341 530.3135 Protein HIRA OS=Homo sapiens OX=9606 GN=HIRA PE=1 SV=2 6 3777.4 - 536666 - - - 1.8042 - 1.431 0.119 - 101.6 6 2 0 0.0019 9 0 0 0 9.51E+06 3.61E+06 - - - 0.6085 0.9878 230117_WJC_METTL3_WT_vs_EV_F03.20271.20271.2 0.00136 12-Sep R.YMDLLWR.Y "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 995.4899 0.28 25208 20271 2 995.496444 498.7522 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 5.84 3777.7 - 331362 - - - 6.6008 - 1.533 0.349 - 241.5 1 2 0 0.0066 7 0 0 0 1.84E+06 6.65E+06 - - - 2.9703 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.20283.20283.2 0.0205 14-Sep R.YLIYDIIK.F sp|O60942|MCE1_HUMAN 1 1039.5954 20.79 25219 20283 2 1039.598382 520.805 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 5.83 3779.2 - 1.52E+06 - - - 2.8838 - 1.409 0.319 - 240.4 1 2 0 0.003 8 0 0 0 1.18E+07 5.66E+05 - - - 2.4303 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.20284.20284.2 2.73E-05 18-Nov R.TLVEDLFADK.H "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1149.5918 1.94 25220 20284 2 1149.598346 575.8032 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.03 3779.4 - 1.47E+06 - - - 5.7333 - 2.102 0.428 - 280.4 1 2 0 0.0066 10 0 0 0 2.50E+07 1.29E+07 - - - 4.2738 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20285.20285.2 0.00211 18-Sep K.DFLLQQTMLR[166.11].V sp|Q04760|LGUL_HUMAN 1 1273.6728 0.84 25221 20285 2 1273.676475 637.8437 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 5.84 3779.5 - 1.20E+06 - - - 2.8751 - 1.853 0.33 - 346.1 1 2 0 0.0037 10 0 0 0 9.16E+06 1.09E+07 - - - 3.1989 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.20286.20286.2 0.00195 18-Oct R.TLVEDLFADK[136.11].H "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1157.606 1.94 25222 20286 2 1157.612325 579.8103 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.03 3779.6 - 924882 - - - 5.5027 - 1.855 0.496 - 245.3 1 2 0 0.0064 10 0 0 0 2.50E+07 1.29E+07 - - - 4.4272 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20290.20290.2 0.00344 20-Oct R.LEYC[160.03]EALAMLR.E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1367.6577 1.24 25226 20290 2 1367.660353 684.8361 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3780.1 - 487943 - - - 1.9084 - 2.068 0.373 - 361.7 1 2 0 0.0026 11 0 0 0 1.41E+07 1.14E+07 - - - 3.7607 1 230117_WJC_METTL3_WT_vs_EV_F03.20291.20291.2 0.000459 20-Dec R.LEYC[160.03]EALAMLR[166.11].E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1377.666 1.24 25227 20291 2 1377.668214 689.8403 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3780.3 - 477476 - - - 1.5976 - 2.556 0.48 - 778 1 2 0 0.0022 11 0 0 0 1.41E+07 1.14E+07 - - - 5.1243 1 230117_WJC_METTL3_WT_vs_EV_F03.20292.20292.2 2.16E-08 16/26 K.GLIGNLYLNDSPLK[136.11].N sp|Q8IW92|GLBL2_HUMAN 1 1523.8439 0.49 25228 20292 2 1523.848661 762.9292 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 5.83 3780.4 - 398801 - - - 3.1283 - 2.951 0.592 - 1174.1 1 2 0 0.0048 14 0 0 0 1.36E+06 2.75E+06 - - - 6.1276 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20293.20293.3 0.017 Nov-36 K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.7 25229 20293 3 1168.709638 390.5762 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3780.5 - 311909 - - - 2.4925 - 2.05 0.327 - 132.3 1 2 0 0.0029 10 0 0 0 1.07E+07 6.29E+06 - - - 4.2813 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.20296.20296.3 0.0313 Aug-36 K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.7 25232 20296 3 1176.723178 393.2476 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3780.9 - 276449 - - - 1.9146 - 1.813 0.283 - 62.1 1 2 0 0.0023 10 0 0 0 1.07E+07 6.29E+06 - - - 3.4322 0.9901 230117_WJC_METTL3_WT_vs_EV_F03.20300.20300.2 1.65 12-Jun K.ADFLIFR.A "sp|Q8IZA0|K319L_HUMAN,tr|E7EN73|E7EN73_HUMAN,tr|C9J519|C9J519_HUMAN" 3 880.4807 -1 25236 20300 2 880.480886 441.2476 Dyslexia-associated protein KIAA0319-like protein OS=Homo sapiens OX=9606 GN=KIAA0319L PE=1 SV=2 5.88 3781.4 - 97429 - - - 0.2237 - 1.224 0.134 - 75.1 1 2 0 0.0002 7 0 0 0 0.00E+00 0.00E+00 - - - 0.6711 1 230117_WJC_METTL3_WT_vs_EV_F03.20304.20304.2 1.77E-05 22-Nov R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 1655.27 25239 20304 2 1603.763423 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3782 - 1.20E+06 - - - -0.3224 - 2.087 0.573 - 375 1 2 0 -0.0005 12 0 0 0 1.13E+10 6.84E+06 - - - 5.2088 1 230117_WJC_METTL3_WT_vs_EV_F03.20306.20306.2 1.52E-06 13/22 R.GNSIIMLEALER[166.11].V "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1354.7154 1.14 25241 20306 2 1354.711109 678.365 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3782.1 - 824480 - - - -3.1719 - 2.806 0.523 - 656.5 1 2 0 -0.0043 12 0 0 0 3.16E+07 2.76E+07 - - - 5.6173 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.20311.20311.3 2.79E-05 Sep-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 10113.65 25244 20311 3 1603.764197 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3782.7 - 5.18E+06 - - - 0.1602 - 1.746 0.46 - 111.3 1 2 0 0.0003 12 0 0 0 4.91E+08 4.85E+04 - - - 5.2133 0.9969 230117_WJC_METTL3_WT_vs_EV_F03.20312.20312.2 0.79 14-Jun R.FDILC[160.03]VVR.D "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1020.5426 1.32 25245 20312 2 1020.54491 511.2786 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 5.83 3782.8 - 3.82E+06 - - - 2.2272 - 1.241 0.244 - 91.8 1 2 0 0.0023 8 0 0 0 1.14E+07 8.67E+06 - - - 1.4937 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.20315.20315.2 0.00536 16-Aug R.YLLLHLLGR.G "sp|Q9UKI8|TLK1_HUMAN,sp|Q86UE8|TLK2_HUMAN,tr|A0A804HJX3|A0A804HJX3_HUMAN,tr|A0A804HKF1|A0A804HKF1_HUMAN,tr|J3KRK0|J3KRK0_HUMAN,tr|A0A804HK10|A0A804HK10_HUMAN,tr|A0A804HIB4|A0A804HIB4_HUMAN,tr|A0A804HJZ9|A0A804HJZ9_HUMAN,tr|J3QLK5|J3QLK5_HUMAN" 9 1096.6757 3.91 25247 20315 2 1096.679293 549.3451 Serine\threonine-protein kinase tousled-like 1 OS=Homo sapiens OX=9606 GN=TLK1 PE=1 SV=2 8.75 3783 - 2.69E+06 - - - 3.2763 - 1.608 0.292 - 226.2 1 2 0 0.0036 9 0 0 0 3.95E+06 1.01E+06 - - - 2.5708 1 230117_WJC_METTL3_WT_vs_EV_F03.20331.20331.2 0.00137 13/20 K.GLAGAVSELLR.S sp|Q9Y490|TLN1_HUMAN 1 1084.6241 1.46 25261 20331 2 1084.621047 543.3193 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 6 3784.7 - 453324 - - - -2.7761 - 2.459 0.465 - 682.9 1 2 0 -0.003 11 0 0 0 1.65E+07 1.13E+07 - - - 4.9086 0.907 230117_WJC_METTL3_WT_vs_EV_F03.20334.20334.2 0.0607 12-Jun R.TFHIFYY.M "sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 3 989.4647 - 25262 20334 2 989.465976 495.7396 Myosin-11 OS=Homo sapiens OX=9606 GN=MYH11 PE=1 SV=3 6.4 3785.1 - 285805 - - - 1.2855 - 1.089 0.381 - 116 1 1 0 0.0013 7 0 0 0 - - - - - 2.1248 1 230117_WJC_METTL3_WT_vs_EV_F03.20335.20335.2 0.000339 16/24 R.LAAVALINAAIQK[136.11].G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1302.8115 0.77 25263 20335 2 1302.810641 652.413 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3785.2 - 651136 - - - -0.6379 - 3.091 0.405 - 939 1 2 0 -0.0008 13 0 0 0 8.07E+06 1.04E+07 - - - 4.9284 1 230117_WJC_METTL3_WT_vs_EV_F03.20336.20336.2 4.78E-06 16/24 R.LAAVALINAAIQK.G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1294.7973 0.77 25264 20336 2 1294.795207 648.4059 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3785.4 - 844802 - - - -1.5948 - 3.444 0.377 - 939.1 1 2 0 -0.0021 13 0 0 0 8.07E+06 1.04E+07 - - - 4.9987 1 230117_WJC_METTL3_WT_vs_EV_F03.20339.20339.2 6.14E-10 16/24 R.WSTLVEDYGMELR.K sp|O00232|PSD12_HUMAN 1 1597.7446 0.16 25267 20339 2 1597.742963 799.8796 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.14 3785.7 - 569955 - - - -1.0521 - 2.813 0.701 - 954.3 1 2 0 -0.0017 13 0 0 0 6.35E+06 3.85E+07 - - - 6.8725 1 230117_WJC_METTL3_WT_vs_EV_F03.20343.20343.2 0.00167 18-Dec R.LSDYLFTLAR.Y "sp|Q96EY8|MMAB_HUMAN,tr|S4R3P5|S4R3P5_HUMAN" 2 1197.6394 2.57 25271 20343 2 1197.635697 599.827 Corrinoid adenosyltransferase OS=Homo sapiens OX=9606 GN=MMAB PE=1 SV=1 5.84 3786.3 - 386340 - - - -3.0702 - 2.37 0.48 - 466.6 1 2 0 -0.0037 10 0 0 0 6.49E+06 2.53E+06 - - - 4.9937 1 230117_WJC_METTL3_WT_vs_EV_F03.20348.20348.2 6.79E-06 24-Dec K.C[160.03]LAPTYLGEFSLR.G "sp|P49366|DHYS_HUMAN,tr|Q5J8M5|Q5J8M5_HUMAN,tr|M0R264|M0R264_HUMAN,tr|A0A087WZK0|A0A087WZK0_HUMAN,tr|M0R1T2|M0R1T2_HUMAN" 5 1525.7599 -1 25276 20348 2 1525.758485 763.8872 Deoxyhypusine synthase OS=Homo sapiens OX=9606 GN=DHPS PE=1 SV=1 5.99 3786.9 - 176314 - - - -0.9274 - 2.204 0.56 - 450 1 2 0 -0.0014 13 0 0 0 0.00E+00 0.00E+00 - - - 5.205 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.20349.20349.3 0.00036 Dec-48 R.LAAVALINAAIQK.G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1294.7973 1.45 25277 20349 3 1294.793995 432.6064 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3787.1 - 165819 - - - -2.5309 - 2.336 0.362 - 278.9 1 2 0 -0.0033 13 0 0 0 3.19E+06 2.20E+06 - - - 4.8754 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.20350.20350.3 0.592 Dec-48 R.LAAVALINAAIQK[136.11].G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1302.8115 1.45 25278 20350 3 1302.812228 435.2778 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3787.2 - 153946 - - - 0.5803 - 2.382 0.179 - 371.7 1 2 0 0.0008 13 0 0 0 3.19E+06 2.20E+06 - - - 2.8887 0.9928 230117_WJC_METTL3_WT_vs_EV_F03.20351.20351.2 0.0729 22-Jul K.TVLMLADQMISR[166.11].L "sp|Q8N752|KC1AL_HUMAN,sp|P48729|KC1A_HUMAN,tr|A0A590UJ43|A0A590UJ43_HUMAN,tr|D6REM4|D6REM4_HUMAN,tr|E7ETM0|E7ETM0_HUMAN,tr|U3KPX3|U3KPX3_HUMAN,tr|A0A5F9W493|A0A5F9W493_HUMAN" 7 1386.7239 1.66 25279 20351 2 1386.7208 694.3692 Casein kinase I isoform alpha-like OS=Homo sapiens OX=9606 GN=CSNK1A1L PE=2 SV=2 5.5 3787.3 - 152001 - - - -2.2081 - 1.521 0.274 - 164.7 1 2 0 -0.0031 12 0 0 0 4.89E+06 2.95E+06 - - - 2.1672 1 230117_WJC_METTL3_WT_vs_EV_F03.20357.20357.2 4.76E-08 17/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 25284 20357 2 1343.613091 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3788 - 1.92E+06 - - - 1.2124 - 3.001 0.547 - 1181.4 1 1 0 0.0016 10 0 0 0 5.39E+07 0.00E+00 - - - 6.1481 1 230117_WJC_METTL3_WT_vs_EV_F03.20358.20358.2 0.000226 13/22 K.TVLLLADQMISR[166.11].L "sp|P48730|KC1D_HUMAN,sp|P49674|KC1E_HUMAN,tr|B0QY36|B0QY36_HUMAN,tr|B0QY34|B0QY34_HUMAN,tr|H7BYT1|H7BYT1_HUMAN,tr|J3QQI9|J3QQI9_HUMAN,tr|A0A669KBC0|A0A669KBC0_HUMAN,tr|H0Y645|H0Y645_HUMAN,tr|B0QY35|B0QY35_HUMAN,tr|H0Y2N6|H0Y2N6_HUMAN" 10 1368.7674 1.72 25285 20358 2 1368.769594 685.391 Casein kinase I isoform delta OS=Homo sapiens OX=9606 GN=CSNK1D PE=1 SV=2 5.5 3788.1 - 1.49E+06 - - - 1.5722 - 2.798 0.478 - 671.2 1 2 0 0.0022 12 0 0 0 6.83E+06 3.97E+06 - - - 5.2781 1 230117_WJC_METTL3_WT_vs_EV_F03.20359.20359.2 0.000571 14/22 K.TVLLLADQMISR.L "sp|P48730|KC1D_HUMAN,sp|P49674|KC1E_HUMAN,tr|B0QY36|B0QY36_HUMAN,tr|B0QY34|B0QY34_HUMAN,tr|H7BYT1|H7BYT1_HUMAN,tr|J3QQI9|J3QQI9_HUMAN,tr|A0A669KBC0|A0A669KBC0_HUMAN,tr|H0Y645|H0Y645_HUMAN,tr|B0QY35|B0QY35_HUMAN,tr|H0Y2N6|H0Y2N6_HUMAN" 10 1358.7592 1.86 25286 20359 2 1358.76165 680.3869 Casein kinase I isoform delta OS=Homo sapiens OX=9606 GN=CSNK1D PE=1 SV=2 5.5 3788.1 - 1.37E+06 - - - 1.8237 - 2.997 0.516 - 867 1 2 0 0.0025 12 0 0 0 7.38E+06 3.97E+06 - - - 5.7394 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.20360.20360.2 0.0041 18-Sep K.INEWLTLVEK[136.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1251.6954 0.95 25287 20360 2 1251.693224 626.855 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.53 3788.2 - 1.33E+06 - - - -1.7696 - 2.048 0.269 - 337.9 1 2 0 -0.0022 10 0 0 0 1.36E+07 1.43E+07 - - - 3.0281 1 230117_WJC_METTL3_WT_vs_EV_F03.20361.20361.2 5.77E-05 20-Dec K.SIDPALSMLIK.S sp|Q9H501|ESF1_HUMAN 1 1186.6631 1.32 25288 20361 2 1186.662173 594.3388 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 5.55 3788.3 - 1.23E+06 - - - -0.8199 - 2.359 0.461 - 340.4 1 2 0 -0.001 11 0 0 0 7.06E+06 5.33E+06 - - - 4.7674 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20362.20362.2 0.00726 22-Nov R.IMVANIEEVLQR.G "sp|O75396|SC22B_HUMAN,tr|A0A087X1A9|A0A087X1A9_HUMAN" 2 1413.765 11.58 25289 20362 2 1413.764399 707.8898 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 4.53 3788.4 - 802412 - - - -0.4145 - 2.493 0.246 - 387.9 1 2 0 -0.0006 12 0 0 0 1.40E+07 1.21E+06 - - - 3.2613 1 230117_WJC_METTL3_WT_vs_EV_F03.20363.20363.3 6.39E-07 14/56 R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 2.24 25290 20363 3 1732.955661 578.6577 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3788.5 - 671334 - - - 2.5708 - 2.614 0.571 - 200.1 1 2 0 0.0045 15 0 0 0 6.56E+06 2.92E+06 - - - 7.4121 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.20369.20369.2 0.074 12-Jul R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 2.22 25294 20369 2 808.431971 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 3789.2 - 396785 - - - -1.3594 - 1.357 0.277 - 105.4 1 2 0 -0.0011 7 0 0 0 1.68E+07 7.58E+06 - - - 2.0539 1 230117_WJC_METTL3_WT_vs_EV_F03.20376.20376.2 0.00237 14/22 K.VESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1404.75 1.31 25301 20376 2 1404.747977 703.3823 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3790 - 655120 - - - -1.4736 - 2.824 0.494 - 698.4 1 2 0 -0.0021 12 0 0 0 2.10E+07 1.61E+07 - - - 5.4206 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.20378.20378.2 0.00394 16-Sep K.ELALSALLK[136.11].F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 964.6048 0.92 25303 20378 2 964.603701 483.3097 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3790.3 - 523842 - - - -1.1735 - 1.827 0.338 - 282.9 1 2 0 -0.0011 9 0 0 0 7.49E+07 8.17E+07 - - - 3.2807 0.9961 230117_WJC_METTL3_WT_vs_EV_F03.20380.20380.2 0.139 13/20 K.SIDPALSMLIK[136.11].S sp|Q9H501|ESF1_HUMAN 1 1194.6773 1.22 25305 20380 2 1194.673834 598.3459 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 5.55 3790.5 - 427187 - - - -2.9397 - 2.119 0.329 - 416.8 1 2 0 -0.0035 11 0 0 0 6.50E+06 5.33E+06 - - - 3.5014 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.20383.20383.3 2.12E-05 19/52 R.HLGLVPLEPGGWLR.R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1542.8671 4.13 25308 20383 3 1542.864725 515.2963 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 6.75 3790.9 - 378256 - - - -1.5283 - 2.901 0.467 - 626 1 2 0 -0.0024 14 0 0 0 1.39E+07 3.38E+06 - - - 6.5764 0.9912 230117_WJC_METTL3_WT_vs_EV_F03.20390.20390.2 0.00119 22-Sep R.IMVANIEEVLQR[166.11].G "sp|O75396|SC22B_HUMAN,tr|A0A087X1A9|A0A087X1A9_HUMAN" 2 1423.7733 -1 25314 20390 2 1423.767309 712.8939 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 4.53 3791.8 - 576986 - - - -4.1762 - 1.922 0.358 - 292.3 1 2 0 -0.0059 12 0 0 0 0.00E+00 0.00E+00 - - - 3.4024 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.20392.20392.2 0.00289 16-Aug K.ELALSALLK.F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 956.5906 0.92 25315 20392 2 956.589777 479.3026 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3791.9 - 7.95E+06 - - - -0.8948 - 1.699 0.347 - 205.1 1 2 0 -0.0009 9 0 0 0 7.49E+07 8.17E+07 - - - 3.1371 1 230117_WJC_METTL3_WT_vs_EV_F03.20394.20394.2 1.06E-07 15/30 K.IITLEEGDIILTGTPK.G sp|Q6P587|FAHD1_HUMAN 1 1711.9608 1.89 25317 20394 2 1711.961394 856.9877 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3792 - 3.62E+06 - - - 0.3657 - 3.223 0.619 - 645.7 1 2 0 0.0006 16 0 0 0 2.73E+07 1.45E+07 - - - 6.49 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.20395.20395.2 0.235 14-Jun K.QELLELFK[136.11].E "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1026.5841 1.27 25318 20395 2 1026.58483 514.2993 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 4.53 3792 - 3.27E+06 - - - 0.713 - 1.316 0.237 - 125.8 1 2 0 0.0007 8 0 0 0 3.60E+07 2.83E+07 - - - 1.6194 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.20396.20396.2 0.124 14-Aug K.QELLELFK.E "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1018.5699 1.27 25319 20396 2 1018.571375 510.2922 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 4.53 3792.1 - 3.00E+06 - - - 1.4501 - 1.62 0.305 - 220.1 1 2 0 0.0015 8 0 0 0 3.60E+07 2.83E+07 - - - 2.7482 1 230117_WJC_METTL3_WT_vs_EV_F03.20398.20398.2 3.86E-07 15/30 R.LMNDMTAVALNYGIYK.Q sp|Q92598|HS105_HUMAN 1 1815.8899 33.71 25321 20398 2 1815.889288 908.9522 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.83 3792.2 - 2.34E+06 - - - -0.3524 - 3.226 0.694 - 611.5 1 2 0 -0.0006 16 0 0 0 3.30E+07 9.78E+05 - - - 7.0462 1 230117_WJC_METTL3_WT_vs_EV_F03.20399.20399.2 4.59E-06 15/30 K.IITLEEGDIILTGTPK[136.11].G sp|Q6P587|FAHD1_HUMAN 1 1719.975 1.89 25322 20399 2 1719.975512 860.9948 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3792.3 - 2.33E+06 - - - 0.3163 - 3.021 0.502 - 512.8 1 2 0 0.0005 16 0 0 0 2.73E+07 1.45E+07 - - - 5.4667 0.9361 230117_WJC_METTL3_WT_vs_EV_F03.20400.20400.2 1.08 12-Jun K.LDDLFLK.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 862.48 1.88 25323 20400 2 862.47898 432.2473 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3792.4 - 2.30E+06 - - - -1.2058 - 1.333 0 - 124.3 1 2 0 -0.001 7 0 0 0 1.43E+07 7.63E+06 - - - -0.0486 1 230117_WJC_METTL3_WT_vs_EV_F03.20402.20402.2 0.0014 14/24 K.LILLITQVTASEK[136.11].T sp|Q15061|WDR43_HUMAN 1 1435.8741 1.01 25325 20402 2 1435.87538 718.9443 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3792.5 - 1.71E+06 - - - 0.8692 - 2.674 0.42 - 645.4 1 2 0 0.0012 13 0 0 0 1.25E+07 1.24E+07 - - - 4.6671 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.20403.20403.2 0.0022 12-Aug K.LWDLYLR.T "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 977.5335 1.65 25326 20403 2 977.534502 489.774 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.84 3792.6 - 1.53E+06 - - - 1.0741 - 1.66 0.157 - 281.9 1 2 0 0.001 7 0 0 0 1.33E+07 8.04E+06 - - - 1.8062 1 230117_WJC_METTL3_WT_vs_EV_F03.20405.20405.2 2.00E-08 22-Nov R.LLTFMGMAVENK[136.11].E "sp|Q7L2H7|EIF3M_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 2 1360.6974 0.83 25328 20405 2 1360.698328 681.356 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6 3792.7 - 1.33E+06 - - - 0.66 - 2.28 0.614 - 380.6 1 2 0 0.0009 12 0 0 0 2.03E+07 2.45E+07 - - - 5.7443 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20407.20407.2 0.000258 20-Nov K.IGPITPLEFYR.E "sp|Q13867|BLMH_HUMAN,tr|K7ESE8|K7ESE8_HUMAN,tr|J3KSD8|J3KSD8_HUMAN,tr|K7ES02|K7ES02_HUMAN" 4 1304.7129 6.79 25330 20407 2 1304.715862 653.3637 Bleomycin hydrolase OS=Homo sapiens OX=9606 GN=BLMH PE=1 SV=1 6 3792.9 - 1.24E+06 - - - 2.2909 - 2.17 0.368 - 394.1 1 2 0 0.003 11 0 0 0 6.27E+07 9.23E+06 - - - 3.8539 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.20411.20411.2 0.121 18-Sep K.ITIAAYLPLK[136.11].A sp|Q8TEM1|PO210_HUMAN 1 1109.694 2.57 25333 20411 2 1109.692782 555.8543 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 8.59 3793.3 - 2.90E+06 - - - -1.0814 - 1.708 0.314 - 183.1 1 2 0 -0.0012 10 0 0 0 1.97E+07 7.66E+06 - - - 2.8541 1 230117_WJC_METTL3_WT_vs_EV_F03.20412.20412.2 0.0461 22-Oct K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.7 25334 20412 2 1317.706588 659.862 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3793.3 - 2.67E+07 - - - -2.115 - 2.232 0.507 - 189.2 1 2 0 -0.0028 12 0 0 0 4.84E+08 6.93E+08 - - - 4.8974 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.20413.20413.2 0.000132 20-Sep K.GVPTGFILPIR[166.11].D "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1178.7051 3 25335 20413 2 1178.702621 590.3598 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 3793.3 - 1.76E+07 - - - -2.1023 - 1.838 0.475 - 341.4 1 2 0 -0.0025 11 0 0 0 1.94E+08 6.47E+07 - - - 4.1952 1 230117_WJC_METTL3_WT_vs_EV_F03.20416.20416.2 5.45E-06 24-Sep K.LFQEDDEIPLYLK[136.11].G "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6RGV5|D6RGV5_HUMAN" 4 1629.8381 1.52 25338 20416 2 1629.833246 815.9263 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 3.92 3793.5 - 8.49E+06 - - - -3.0028 - 1.886 0.545 - 196.1 1 2 0 -0.0049 13 0 0 0 5.82E+07 3.83E+07 - - - 4.6932 1 230117_WJC_METTL3_WT_vs_EV_F03.20417.20417.2 2.14E-07 22-Dec R.LLTFMGMAVENK.E "sp|Q7L2H7|EIF3M_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 2 1352.6832 0.83 25339 20417 2 1352.680835 677.3489 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6 3793.6 - 7.69E+06 - - - -1.7706 - 2.415 0.573 - 530.2 1 2 0 -0.0024 12 0 0 0 2.03E+07 2.45E+07 - - - 5.5923 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.20419.20419.2 0.000224 18-Sep K.ITIAAYLPLK.A sp|Q8TEM1|PO210_HUMAN 1 1101.6798 2.57 25341 20419 2 1101.677901 551.8472 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 8.59 3793.8 - 6.75E+06 - - - -1.7074 - 2.013 0.455 - 208.4 1 2 0 -0.0019 10 0 0 0 1.97E+07 7.66E+06 - - - 4.3539 0.9882 230117_WJC_METTL3_WT_vs_EV_F03.20420.20420.2 0.0224 18-Sep K.GPDWILGEIK.T "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 6 1126.6023 2.39 25342 20420 2 1126.598234 564.3084 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 4.37 3793.9 - 6.16E+06 - - - -3.5736 - 1.726 0.268 - 247 1 2 0 -0.004 10 0 0 0 1.51E+07 6.33E+06 - - - 2.5427 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20421.20421.2 5.93E-05 22-Aug K.VESLQEEIAFLK[136.11].K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1412.7642 1.31 25343 20421 2 1412.764473 707.3894 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3794 - 4.52E+06 - - - 0.16 - 2.081 0.46 - 164 1 2 0 0.0002 12 0 0 0 2.10E+07 1.61E+07 - - - 4.3667 1 230117_WJC_METTL3_WT_vs_EV_F03.20422.20422.2 2.43E-05 22-Oct K.SLLVNPVLFPNR.E sp|Q9BUB7|TMM70_HUMAN 1 1367.7925 2.24 25344 20422 2 1367.788431 684.9035 "Transmembrane protein 70, mitochondrial OS=Homo sapiens OX=9606 GN=TMEM70 PE=1 SV=2" 9.47 3794.1 - 4.15E+06 - - - -2.9902 - 2.192 0.485 - 383.8 1 2 0 -0.0041 12 0 0 0 7.42E+06 3.31E+06 - - - 4.6869 0.9916 230117_WJC_METTL3_WT_vs_EV_F03.20423.20423.2 0.0271 18-Jun K.LVFPQDLLEK[136.11].G "sp|Q8TCT9|HM13_HUMAN,tr|A0A3B3IT72|A0A3B3IT72_HUMAN,tr|A0A0S2Z6F0|A0A0S2Z6F0_HUMAN,tr|A0A3B3IUB5|A0A3B3IUB5_HUMAN,tr|A0A075B6F6|A0A075B6F6_HUMAN" 5 1208.6896 1.49 25345 20423 2 1208.687484 605.3521 Minor histocompatibility antigen H13 OS=Homo sapiens OX=9606 GN=HM13 PE=1 SV=1 4.37 3794.2 - 4.04E+06 - - - -1.7713 - 1.347 0.256 - 77 1 2 0 -0.0021 10 0 0 0 1.73E+07 1.16E+07 - - - 1.7626 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20424.20424.2 0.000779 20-Oct R.GVTYLFPIQVK.T sp|Q9BQ39|DDX50_HUMAN 1 1263.7227 -1 25346 20424 2 1263.724967 632.8686 ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1 8.59 3794.3 - 3.81E+06 - - - 1.786 - 1.909 0.369 - 397 1 2 0 0.0023 11 0 0 0 0.00E+00 0.00E+00 - - - 3.5149 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.20426.20426.3 0.000227 Nov-60 K.IITLEEGDIILTGTPK.G sp|Q6P587|FAHD1_HUMAN 1 1711.9608 1.67 25348 20426 3 1711.962529 571.6609 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3794.5 - 2.86E+06 - - - 1.0286 - 2.396 0.457 - 175.9 1 2 0 0.0018 16 0 0 0 5.77E+06 3.46E+06 - - - 5.8767 1 230117_WJC_METTL3_WT_vs_EV_F03.20427.20427.2 4.64E-06 15/26 R.WSSMEIMEAYSVAR.Q "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|Q5TG81|Q5TG81_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 5 1658.7433 1.76 25349 20427 2 1658.739995 830.3789 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 4.53 3794.6 - 2.71E+06 - - - -1.9708 - 2.698 0.635 - 661.6 1 2 0 -0.0033 14 0 0 0 8.50E+06 4.82E+06 - - - 6.2207 1 230117_WJC_METTL3_WT_vs_EV_F03.20428.20428.2 3.51E-08 15/28 K.GVYPDLLATSGDYLR[166.11].V sp|P61962|DCAF7_HUMAN 1 1648.8336 2.06 25350 20428 2 1648.82276 825.4241 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3794.7 - 2.29E+06 - - - -6.5786 - 2.649 0.642 - 465.6 1 2 0 -0.0108 15 0 0 0 4.67E+07 2.27E+07 - - - 6.1745 0.9938 230117_WJC_METTL3_WT_vs_EV_F03.20432.20432.2 0.289 14-Jun -.MLPLSLLK.T "sp|Q9Y4Z0|LSM4_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 913.5671 7.95 25353 20432 2 913.567006 457.7908 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 8.5 3795.2 - 1.16E+06 - - - -0.0602 - 1.168 0.22 - 108.4 1 2 0 -0.0001 8 0 0 0 1.52E+07 1.91E+06 - - - 1.1343 1 230117_WJC_METTL3_WT_vs_EV_F03.20433.20433.2 4.08E-06 18-Sep -.MFLYNLTLQR.A "sp|Q15393|SF3B3_HUMAN,tr|H3BMB0|H3BMB0_HUMAN,tr|I3L4G7|I3L4G7_HUMAN" 3 1297.6853 0.15 25354 20433 2 1297.684401 649.8499 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.5 3795.2 - 8.76E+06 - - - -0.6758 - 2.145 0.515 - 275.5 1 2 0 -0.0009 10 0 0 0 5.94E+07 4.08E+08 - - - 4.9747 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.20434.20434.3 6.02E-06 Nov-44 K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.69 25355 20434 3 1317.708158 440.2437 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3795.3 - 5.39E+06 - - - -0.9236 - 2.089 0.476 - 235 1 2 0 -0.0012 12 0 0 0 1.89E+07 2.75E+07 - - - 5.8886 0.9929 230117_WJC_METTL3_WT_vs_EV_F03.20436.20436.2 0.0272 18-Sep K.VGDPVYLLGQ.- "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN" 2 1059.5601 - 25357 20436 2 1059.557358 530.7873 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 3.8 3795.5 - 2.99E+06 - - - -2.5511 - 1.699 0.255 - 222.9 1 2 0 -0.0027 10 0 0 0 - - - - - 2.4031 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20437.20437.2 0.011 20-Sep R.IISLETYNLLR.E "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1333.7606 1.97 25358 20437 2 1333.761789 667.8876 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 3795.6 - 2.07E+06 - - - 0.9275 - 1.785 0.256 - 160.5 1 2 0 0.0012 11 0 0 0 2.46E+07 1.25E+07 - - - 2.4989 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.20439.20439.2 0.000696 24-Dec R.LELYAQATEALLK.T "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1461.8079 2.19 25360 20439 2 1461.809653 731.9112 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 4.53 3795.8 - 1.60E+06 - - - 1.2019 - 2.382 0.43 - 249.1 1 2 0 0.0018 13 0 0 0 1.17E+07 5.35E+06 - - - 4.444 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.20440.20440.2 0.00071 20-Jul K.C[160.03]GPMVLDALIK.L "sp|P21912|SDHB_HUMAN,tr|A0A087WWT1|A0A087WWT1_HUMAN,tr|A0A087WXX8|A0A087WXX8_HUMAN" 3 1215.6356 2.04 25361 20440 2 1215.634838 608.8251 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.83 3795.9 - 0 - - - -0.5865 - 1.441 0.374 - 66.3 1 2 0 -0.0007 11 0 0 0 7.07E+06 3.47E+06 - - - 2.7915 0.9738 230117_WJC_METTL3_WT_vs_EV_F03.20441.20441.2 0.0539 24-Oct R.LELYAQATEALLK[136.11].T "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1469.8221 2.19 25362 20441 2 1469.814868 735.9183 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 4.53 3796.1 - 760796 - - - -4.9176 - 1.808 0.273 - 219.8 1 2 0 -0.0072 13 0 0 0 1.17E+07 5.35E+06 - - - 2.5751 1 230117_WJC_METTL3_WT_vs_EV_F03.20445.20445.2 0.00121 22-Dec K.TVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1309.6952 0.7 25364 20445 2 1309.691318 655.8549 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3796.6 - 2.21E+08 - - - -2.945 - 2.516 0.532 - 289.9 1 2 0 -0.0039 12 0 0 0 4.84E+08 6.93E+08 - - - 5.3968 1 230117_WJC_METTL3_WT_vs_EV_F03.20446.20446.2 0.00842 13/28 K.GVYPDLLATSGDYLR.V sp|P61962|DCAF7_HUMAN 1 1638.8253 2.06 25365 20446 2 1638.81947 820.4199 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3796.7 - 1.93E+07 - - - -3.58 - 2.472 0.552 - 415 1 2 0 -0.0059 15 0 0 0 4.67E+07 2.27E+07 - - - 5.3413 1 230117_WJC_METTL3_WT_vs_EV_F03.20448.20448.2 1.62E-06 24-Sep K.LFQEDDEIPLYLK.G "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6RGV5|D6RGV5_HUMAN" 4 1621.8239 -1 25367 20448 2 1621.820718 811.9192 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 3.92 3796.8 - 1.92E+07 - - - -1.9867 - 1.951 0.539 - 191.1 1 2 0 -0.0032 13 0 0 0 0.00E+00 0.00E+00 - - - 4.7364 1 230117_WJC_METTL3_WT_vs_EV_F03.20449.20449.2 9.68E-07 22-Dec R.VALDMTTLTIMR.Y "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 4 1363.7203 1.36 25368 20449 2 1363.715642 682.8674 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.81 3796.9 - 1.27E+07 - - - -3.4472 - 2.433 0.493 - 620.8 1 2 0 -0.0047 12 0 0 0 2.44E+07 1.80E+07 - - - 5.0203 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20450.20450.3 4.11E-06 Dec-44 K.TVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1309.6952 0.69 25369 20450 3 1309.692314 437.5723 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3796.9 - 9.83E+06 - - - -2.1845 - 1.944 0.498 - 241.5 1 2 0 -0.0029 12 0 0 0 1.89E+07 2.75E+07 - - - 5.934 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.20451.20451.2 0.00479 14-Jul R.EIFNFVLK[136.11].A sp|P78527|PRKDC_HUMAN 1 1016.5786 0.92 25370 20451 2 1016.578081 509.2966 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6.1 3797 - 9.28E+06 - - - -0.5282 - 1.388 0.377 - 183 1 2 0 -0.0005 8 0 0 0 1.95E+07 2.11E+07 - - - 2.8142 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.20452.20452.2 0.0273 14-Jul R.LLDFLNVK[136.11].N sp|Q8NDZ4|DIK2A_HUMAN 1 968.5786 0.81 25371 20452 2 968.576102 485.2966 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 5.84 3797 - 8.14E+06 - - - -2.5976 - 1.554 0.389 - 93.4 1 2 0 -0.0025 8 0 0 0 1.23E+07 1.51E+07 - - - 3.2429 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.20453.20453.2 3.66E-05 22-Nov R.VALDMTTLTIMR[166.11].Y "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 4 1373.7286 1.36 25372 20453 2 1373.727473 687.8716 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.81 3797.1 - 8.06E+06 - - - -0.8299 - 2.425 0.382 - 420.8 1 2 0 -0.0011 12 0 0 0 2.44E+07 1.80E+07 - - - 4.1929 1 230117_WJC_METTL3_WT_vs_EV_F03.20454.20454.2 4.53E-06 22-Nov R.IRDLLYEQYAIV.- sp|Q9P2I0|CPSF2_HUMAN 1 1494.8082 1.42 25373 20454 2 1494.805876 748.4114 Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2 4.37 3797.2 - 6.65E+06 - - - -1.5748 - 2.193 0.509 - 336.6 1 2 1 -0.0024 12 0 0 0 1.37E+07 9.69E+06 - - - 4.8659 0.9918 230117_WJC_METTL3_WT_vs_EV_F03.20456.20456.2 0.00461 18-Aug K.AEVLWLMGAK.S sp|O94906|PRP6_HUMAN 1 1116.6002 0.88 25375 20456 2 1116.595856 559.3074 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.05 3797.4 - 6.34E+06 - - - -3.8474 - 1.663 0.373 - 169.1 1 2 0 -0.0043 10 0 0 0 2.09E+07 2.38E+07 - - - 3.2144 1 230117_WJC_METTL3_WT_vs_EV_F03.20458.20458.2 5.95E-07 22-Oct R.IR[166.11]DLLYEQYAIV.- sp|Q9P2I0|CPSF2_HUMAN 1 1504.8165 1.42 25377 20458 2 1504.81173 753.4155 Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2 4.37 3797.5 - 4.90E+06 - - - -3.1698 - 2.029 0.549 - 202.4 1 2 1 -0.0048 12 0 0 0 1.37E+07 9.69E+06 - - - 4.9561 1 230117_WJC_METTL3_WT_vs_EV_F03.20461.20461.2 5.30E-07 15/34 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 2.72 25380 20461 2 1968.067278 985.0433 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3797.8 - 4.26E+06 - - - -2.4247 - 2.356 0.552 - 414.7 1 2 0 -0.0048 18 0 0 0 1.42E+07 5.24E+06 - - - 5.2235 0.9832 230117_WJC_METTL3_WT_vs_EV_F03.20463.20463.2 0.0303 14-Jul R.EVMLILIR[166.11].E sp|O75533|SF3B1_HUMAN 1 995.6077 0.63 25382 20463 2 995.603385 498.8111 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.1 3798.1 - 3.58E+06 - - - -4.328 - 1.537 0.316 - 196.2 1 2 0 -0.0043 8 0 0 0 5.24E+06 8.27E+06 - - - 2.67 0.9943 230117_WJC_METTL3_WT_vs_EV_F03.20466.20466.2 0.000334 18-Sep K.FTMVQVWPVR.Q "sp|P38606|VATA_HUMAN,tr|C9JA17|C9JA17_HUMAN,tr|C9JVW8|C9JVW8_HUMAN" 3 1261.6641 5.99 25384 20466 2 1261.659485 631.8394 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 9.75 3798.4 - 799805 - - - -3.6967 - 1.923 0.373 - 343.6 1 2 0 -0.0047 10 0 0 0 9.81E+06 1.64E+06 - - - 3.6197 0.9607 230117_WJC_METTL3_WT_vs_EV_F03.20467.20467.2 0.00158 18-Aug K.FTMVQVWPVR[166.11].Q "sp|P38606|VATA_HUMAN,tr|C9JA17|C9JA17_HUMAN,tr|C9JVW8|C9JVW8_HUMAN" 3 1271.6724 -1 25385 20467 2 1271.684093 636.8435 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 9.75 3798.5 - 2.47E+06 - - - 9.18 - 1.436 0.366 - 145.9 1 2 0 0.0117 10 0 0 0 0.00E+00 0.00E+00 - - - 2.7507 1 230117_WJC_METTL3_WT_vs_EV_F03.20470.20470.2 4.97E-07 15/26 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.55 25388 20470 2 1487.778589 744.8959 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3798.6 - 1.54E+06 - - - 0.8899 - 2.679 0.489 - 576.6 1 2 0 0.0013 14 0 0 0 1.96E+07 1.26E+07 - - - 5.1253 0.9955 230117_WJC_METTL3_WT_vs_EV_F03.20471.20471.2 0.0223 14-Aug R.EVMLILIR.E sp|O75533|SF3B1_HUMAN 1 985.5994 0.63 25389 20471 2 985.598143 493.807 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.1 3798.8 - 369003 - - - -1.2997 - 1.509 0.241 - 276.7 1 2 0 -0.0013 8 0 0 0 5.24E+06 8.27E+06 - - - 2.0615 0.9976 230117_WJC_METTL3_WT_vs_EV_F03.20473.20473.2 6.29E-05 Nov-34 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 2.72 25391 20473 2 1976.080736 989.0504 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3799 - 0 - - - -2.7904 - 1.877 0.503 - 228.3 1 2 0 -0.0055 18 0 0 0 1.42E+07 5.24E+06 - - - 4.3025 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.20474.20474.2 0.124 20-Jul K.ILPGLYIGNFK.D "sp|Q9NRW4|DUS22_HUMAN,tr|S4R459|S4R459_HUMAN" 2 1233.7121 -1 25392 20474 2 1233.711864 617.8633 Dual specificity protein phosphatase 22 OS=Homo sapiens OX=9606 GN=DUSP22 PE=1 SV=1 8.59 3799.2 - 349493 - - - -0.2278 - 1.44 0.234 - 83.7 1 2 0 -0.0003 11 0 0 0 0.00E+00 0.00E+00 - - - 1.7557 0.9711 230117_WJC_METTL3_WT_vs_EV_F03.20476.20476.2 0.0898 12-Jun R.YILNFLR.T "sp|Q719H9|KCTD1_HUMAN,sp|Q4G0X4|KCD21_HUMAN,tr|J3KSG1|J3KSG1_HUMAN,tr|E9PK99|E9PK99_HUMAN,tr|E9PJJ5|E9PJJ5_HUMAN,tr|A0A2U3U043|A0A2U3U043_HUMAN,tr|E9PRT1|E9PRT1_HUMAN,tr|J3QRK1|J3QRK1_HUMAN,tr|E9PMS5|E9PMS5_HUMAN" 9 937.5385 -1 25394 20476 2 937.535652 469.7765 BTB\POZ domain-containing protein KCTD1 OS=Homo sapiens OX=9606 GN=KCTD1 PE=1 SV=1 8.75 3799.4 - 0 - - - -3.0783 - 1.382 0.18 - 84.4 1 2 0 -0.0029 7 0 0 0 0.00E+00 0.00E+00 - - - 1.3947 1 230117_WJC_METTL3_WT_vs_EV_F03.20486.20486.2 0.000142 18-Dec K.VLEAELLVLR[166.11].Q sp|P07196|NFL_HUMAN 1 1163.7153 0.36 25402 20486 2 1163.716259 582.8649 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.53 3800.5 - 946147 - - - 0.7983 - 2.405 0.476 - 476.5 1 2 0 0.0009 10 0 0 0 1.35E+06 3.78E+06 - - - 5.006 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.20489.20489.2 0.0314 12-Aug R.WQFLTLR.E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 962.5338 2.81 25405 20489 2 962.537205 482.2742 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 9.75 3800.9 - 805409 - - - 3.551 - 1.487 0.376 - 264.2 1 2 0 0.0034 7 0 0 0 4.53E+06 1.61E+06 - - - 3.0742 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20495.20495.2 0.000128 22-Aug K.FLETVELQISLK.N sp|P62906|RL10A_HUMAN 1 1418.8021 1.11 25411 20495 2 1418.805381 710.4083 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.53 3801.6 - 430850 - - - 2.3252 - 1.723 0.448 - 124.9 1 2 0 0.0033 12 0 0 0 6.99E+06 6.27E+06 - - - 3.7804 1 230117_WJC_METTL3_WT_vs_EV_F03.20496.20496.2 0.000463 13/22 K.FLETVELQISLK[136.11].N sp|P62906|RL10A_HUMAN 1 1426.8163 1.11 25412 20496 2 1426.815671 714.4154 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.53 3801.8 - 370664 - - - -0.4282 - 2.526 0.535 - 491.9 1 2 0 -0.0006 12 0 0 0 6.99E+06 6.27E+06 - - - 5.4305 0.991 230117_WJC_METTL3_WT_vs_EV_F03.20500.20500.2 0.53 14-Jul R.KIPVPANR[166.11].Y "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 903.553 - 25415 20500 2 903.554577 452.7838 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 11 3802.4 - 17517.5 - - - 1.794 - 1.482 0.048 - 122.4 1 2 0 0.0016 8 0 0 0 - - - - - 0.5815 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.20502.20502.2 1.39E-07 20-Dec K.GIFNGFSVTLK[136.11].E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1189.6587 1.97 25417 20502 2 1189.659728 595.8366 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3802.7 - 595192 - - - 0.8986 - 2.263 0.375 - 311.7 1 2 0 0.0011 11 0 0 0 7.73E+06 3.92E+06 - - - 4.0198 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20503.20503.2 2.05E-06 20-Dec K.GIFNGFSVTLK.E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1181.6445 1.97 25418 20503 2 1181.64281 591.8295 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3802.8 - 561078 - - - -1.3955 - 2.079 0.478 - 357.4 1 2 0 -0.0016 11 0 0 0 7.73E+06 3.92E+06 - - - 4.5509 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20504.20504.2 0.503 20-Dec K.FMELLEPLNER[166.11].K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1399.7045 0.88 25419 20504 2 1399.704228 700.8595 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.25 3803 - 496462 - - - -0.1993 - 1.757 0.442 - 260.6 1 2 0 -0.0003 11 0 0 0 1.23E+06 1.39E+06 - - - 3.8302 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.20505.20505.3 0.00127 15/52 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 2.18 25420 20505 3 1487.774691 496.933 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3803.1 - 470465 - - - -1.7301 - 1.745 0.363 - 137.4 1 2 0 -0.0026 14 0 0 0 2.81E+06 1.29E+06 - - - 4.066 0.979 230117_WJC_METTL3_WT_vs_EV_F03.20511.20511.3 0.0727 Oct-40 R.LHQLLALTLWK.E "sp|Q7L5D6|GET4_HUMAN,tr|C9JPA8|C9JPA8_HUMAN,tr|C9JHN8|C9JHN8_HUMAN,tr|C9JY46|C9JY46_HUMAN" 4 1334.8074 9.96 25426 20511 3 1334.804526 445.9431 Golgi to ER traffic protein 4 homolog OS=Homo sapiens OX=9606 GN=GET4 PE=1 SV=1 8.76 3803.9 - 185110 - - - -2.1853 - 1.279 0.26 - 65.9 1 2 0 -0.0029 11 0 0 0 1.38E+06 1.39E+05 - - - 2.137 1 230117_WJC_METTL3_WT_vs_EV_F03.20514.20514.2 3.87E-06 13/24 R.GAVGALLVYDIAK[136.11].H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1296.7533 1.59 25429 20514 2 1296.758203 649.3839 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3804.3 - 175441 - - - 3.7902 - 2.896 0.506 - 801.2 1 2 0 0.0049 13 0 0 0 6.66E+07 4.20E+07 - - - 5.5058 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20515.20515.2 0.00919 20-Nov R.LLGAALPLLTK[136.11].E "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1116.7362 1.16 25430 20515 2 1116.736406 559.3754 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 8.75 3804.4 - 120555 - - - 0.2006 - 2.274 0.413 - 224 1 2 0 0.0002 11 0 0 0 2.95E+06 2.54E+06 - - - 4.3138 0.9878 230117_WJC_METTL3_WT_vs_EV_F03.20516.20516.2 0.00739 12-Aug R.WQFLTLR[166.11].E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 972.5421 2.81 25431 20516 2 972.538346 487.2783 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 9.75 3804.5 - 77531.8 - - - -3.8158 - 1.448 0.333 - 264.8 1 2 0 -0.0037 7 0 0 0 4.53E+06 1.61E+06 - - - 2.6723 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.20519.20519.2 0.00304 14-Jul K.AWGILTFK[136.11].G "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 942.5418 1.39 25433 20519 2 942.541099 472.2782 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 8.8 3804.8 - 5.14E+06 - - - -0.7851 - 1.515 0.416 - 249.2 1 2 0 -0.0007 8 0 0 0 6.94E+07 5.01E+07 - - - 3.3662 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.20520.20520.2 0.0377 14-May K.AWGILTFK.G "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 934.5276 1.39 25434 20520 2 934.528169 468.2711 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 8.8 3804.8 - 6.38E+06 - - - 0.5671 - 1.231 0.3 - 119.7 1 2 0 0.0005 8 0 0 0 6.94E+07 5.01E+07 - - - 1.8834 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20524.20524.2 0.000489 16-Aug R.LVSYYYFLR.F sp|Q7LGA3|HS2ST_HUMAN 1 1222.6386 0.89 25438 20524 2 1222.639928 612.3266 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 8.5 3805.1 - 595041 - - - 1.0486 - 1.582 0.463 - 241.3 1 2 0 0.0013 9 0 0 0 1.01E+07 1.13E+07 - - - 3.7873 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20525.20525.2 0.135 14-Aug R.VLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 881.6062 1.35 25439 20525 2 881.606681 441.8104 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3805.1 - 593417 - - - 0.5195 - 1.795 0.321 - 232.3 1 2 0 0.0005 8 0 0 0 3.29E+07 2.43E+07 - - - 3.1761 0.9954 230117_WJC_METTL3_WT_vs_EV_F03.20528.20528.2 0.0106 20-Sep K.ESPLLFPYYPR.K sp|Q9UJX5|APC4_HUMAN 1 1380.7078 1.14 25442 20528 2 1380.713194 691.3612 Anaphase-promoting complex subunit 4 OS=Homo sapiens OX=9606 GN=ANAPC4 PE=1 SV=2 6.1 3805.4 - 341097 - - - 3.9154 - 1.4 0.286 - 141.7 1 2 0 0.0054 11 0 0 0 1.70E+06 1.49E+06 - - - 2.0619 1 230117_WJC_METTL3_WT_vs_EV_F03.20533.20533.2 8.77E-08 14/24 R.GAVGALLVYDIAK.H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1288.7391 1.59 25445 20533 2 1288.736938 645.3768 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3806.1 - 3.75E+06 - - - -1.6683 - 3.01 0.446 - 1023.1 1 2 0 -0.0022 13 0 0 0 6.66E+07 4.20E+07 - - - 5.1626 1 230117_WJC_METTL3_WT_vs_EV_F03.20534.20534.2 2.71E-06 16/24 K.ILESSQTLLSVLK.R "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1429.8392 3.14 25446 20534 2 1429.835988 715.9269 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 6 3806.3 - 1.05E+06 - - - -2.2436 - 2.866 0.557 - 611.1 1 2 0 -0.0032 13 0 0 0 2.96E+07 9.43E+06 - - - 5.8563 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.20535.20535.2 0.456 14-Sep R.VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 891.6145 1.36 25447 20535 2 891.614672 446.8145 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3806.4 - 5.05E+06 - - - 0.2008 - 1.983 0.246 - 358.2 1 2 0 0.0002 8 0 0 0 3.30E+07 2.43E+07 - - - 2.9227 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20536.20536.2 0.000361 16-Sep K.C[160.03]MPTFQFFK.K sp|P10599|THIO_HUMAN 1 1204.5409 2.77 25448 20536 2 1204.541548 603.2777 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3806.5 - 2.10E+06 - - - 0.5189 - 1.53 0.477 - 201.8 1 2 0 0.0006 9 0 0 0 3.04E+07 1.10E+07 - - - 3.7942 0.9922 230117_WJC_METTL3_WT_vs_EV_F03.20537.20537.2 0.00865 16-Jul K.C[160.03]MPTFQFFK[136.11].K sp|P10599|THIO_HUMAN 1 1212.5551 2.77 25449 20537 2 1212.553524 607.2848 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3806.6 - 752031 - - - -1.3187 - 1.183 0.278 - 99.6 1 2 0 -0.0016 9 0 0 0 3.04E+07 1.10E+07 - - - 1.58 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20538.20538.2 0.0108 16-Sep R.LVFGFLNGR.A "sp|P00491|PNPH_HUMAN,tr|G3V2H3|G3V2H3_HUMAN,tr|G3V5M2|G3V5M2_HUMAN" 3 1021.5709 4.59 25450 20538 2 1021.572838 511.7927 Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2 9.75 3806.7 - 701077 - - - 1.8961 - 1.394 0.412 - 254.3 1 2 0 0.0019 9 0 0 0 3.87E+06 8.44E+05 - - - 3.0444 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20539.20539.2 0.000485 18-Oct R.IYLDMLNVYK.C "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 11 1270.6631 1.55 25451 20539 2 1270.663971 636.3388 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.83 3806.9 - 593385 - - - 0.6493 - 1.897 0.332 - 256.1 1 2 0 0.0008 10 0 0 0 2.17E+07 1.40E+07 - - - 3.2801 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.20541.20541.2 0.0818 18-Aug R.IYLDMLNVYK[136.11].C "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 11 1278.6773 1.83 25453 20541 2 1278.67913 640.3459 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.83 3807.1 - 508451 - - - 1.3952 - 1.632 0.26 - 172 1 2 0 0.0018 10 0 0 0 2.59E+07 1.42E+07 - - - 2.328 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20544.20544.2 0.0233 20-Oct R.LLGAALPLLTK.E "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1108.722 1.16 25456 20544 2 1108.722927 555.3683 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 8.75 3807.5 - 476350 - - - 0.8523 - 1.725 0.351 - 145.6 1 2 0 0.0009 11 0 0 0 2.95E+06 2.54E+06 - - - 3.1082 0.99 230117_WJC_METTL3_WT_vs_EV_F03.20546.20546.2 0.547 16-Jun K.DLSDFPLIK.K "sp|P20585|MSH3_HUMAN,tr|A0A590UJN8|A0A590UJN8_HUMAN,tr|A0A590UKC9|A0A590UKC9_HUMAN,tr|A0A590UJW0|A0A590UJW0_HUMAN" 4 1046.5648 1.44 25458 20546 2 1046.566824 524.2897 DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4 4.21 3807.8 - 352721 - - - 1.9225 - 1.152 0.146 - 74.6 1 2 0 0.002 9 0 0 0 1.55E+06 1.08E+06 - - - 0.5281 1 230117_WJC_METTL3_WT_vs_EV_F03.20547.20547.2 0.000173 13/26 K.IPVTIITGYLGAGK.T "sp|Q5RIA9|CBWD5_HUMAN,sp|Q9BRT8|CBWD1_HUMAN,sp|Q5JTY5|CBWD3_HUMAN,sp|Q4V339|CBWD6_HUMAN,sp|Q8IUF1|CBWD2_HUMAN,tr|A0A087WZQ3|A0A087WZQ3_HUMAN,tr|Q5JTY2|Q5JTY2_HUMAN,tr|Q6NVZ8|Q6NVZ8_HUMAN,tr|A0A0B4J2E3|A0A0B4J2E3_HUMAN,tr|A0A087X140|A0A087X140_HUMAN,tr|F8WEU0|F8WEU0_HUMAN,tr|E7EUZ7|E7EUZ7_HUMAN,tr|F8WEG4|F8WEG4_HUMAN,tr|A0A087WYD2|A0A087WYD2_HUMAN,tr|A0A0A0MRU4|A0A0A0MRU4_HUMAN,tr|Q5RIB0|Q5RIB0_HUMAN,tr|H0Y5V3|H0Y5V3_HUMAN,tr|A0A0A6YYH9|A0A0A6YYH9_HUMAN,tr|A0A087WWG3|A0A087WWG3_HUMAN,tr|A0A087WTC0|A0A087WTC0_HUMAN,tr|C9J3G2|C9J3G2_HUMAN,tr|F2Z2T4|F2Z2T4_HUMAN,tr|Q5RIB5|Q5RIB5_HUMAN" 23 1401.8232 7.53 25459 20547 2 1401.820383 701.9189 COBW domain-containing protein 5 OS=Homo sapiens OX=9606 GN=CBWD5 PE=2 SV=1 8.59 3807.9 - 317155 - - - -1.9753 - 2.734 0.413 - 641.1 1 2 0 -0.0028 14 0 0 0 3.63E+06 4.82E+05 - - - 4.6145 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.20548.20548.2 0.0745 14-Sep K.VFLDVLMK[136.11].E sp|Q14684|RRP1B_HUMAN 1 971.5605 -1 25460 20548 2 971.561357 486.7875 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.81 3808 - 303120 - - - 0.8564 - 1.853 0.254 - 242 1 2 0 0.0008 8 0 0 0 0.00E+00 0.00E+00 - - - 2.777 0.9848 230117_WJC_METTL3_WT_vs_EV_F03.20549.20549.3 1.41E-06 14/36 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 25461 20549 3 1343.612068 448.8778 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3808.2 - 271771 - - - 0.451 - 1.968 0.565 - 372 1 1 0 0.0006 10 0 0 0 1.24E+06 0.00E+00 - - - 6.8162 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20550.20550.2 0.000455 26-Jul K.VTVNPGLLVPLDVK.L sp|Q6KB66|K2C80_HUMAN 1 1462.8759 -1 25462 20550 2 1462.879262 732.4452 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 5.81 3808.3 - 268421 - - - 2.2873 - 1.581 0.342 - 121.4 1 2 0 0.0033 14 0 0 0 0.00E+00 0.00E+00 - - - 2.7154 0.9635 230117_WJC_METTL3_WT_vs_EV_F03.20551.20551.2 4.02 16-Jul R.LVFGFLNGR[166.11].A "sp|P00491|PNPH_HUMAN,tr|G3V2H3|G3V2H3_HUMAN,tr|G3V5M2|G3V5M2_HUMAN" 3 1031.5792 -1 25463 20551 2 1031.57936 516.7969 Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2 9.75 3808.4 - 237389 - - - 0.1832 - 1.22 0.024 - 102 1 2 0 0.0002 9 0 0 0 0.00E+00 0.00E+00 - - - -0.2065 1 230117_WJC_METTL3_WT_vs_EV_F03.20552.20552.2 1.70E-08 18/28 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.36 25464 20552 2 1548.925796 775.4692 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3808.6 - 231501 - - - 1.2054 - 3.589 0.635 - 787.2 1 2 0 0.0019 15 0 0 0 1.97E+08 1.44E+08 - - - 6.8722 1 230117_WJC_METTL3_WT_vs_EV_F03.20555.20555.2 1.82E-06 18/28 K.LLGASELPIVTPALR[166.11].A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1558.9322 1.36 25466 20555 2 1558.936827 780.4734 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3808.9 - 3.79E+06 - - - 2.9687 - 3.592 0.55 - 679.6 1 2 0 0.0046 15 0 0 0 1.97E+08 1.44E+08 - - - 6.2456 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.20556.20556.2 0.00172 16-Sep R.FTGLESIFR[166.11].A sp|Q8N4Q0|PTGR3_HUMAN 1 1078.5687 0.73 25467 20556 2 1078.568018 540.2916 Prostaglandin reductase 3 OS=Homo sapiens OX=9606 GN=ZADH2 PE=1 SV=1 6 3808.9 - 1.37E+07 - - - -0.5999 - 1.666 0.473 - 232.3 1 2 0 -0.0006 9 0 0 0 3.73E+07 5.13E+07 - - - 4.0111 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20557.20557.2 0.000115 18-Oct K.DLIGVQNLLK[136.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1119.6743 0.93 25468 20557 2 1119.674035 560.8444 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3809 - 6.92E+06 - - - -0.2456 - 2.197 0.419 - 282.3 1 2 0 -0.0003 10 0 0 0 1.96E+07 2.11E+07 - - - 4.3327 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.20558.20558.2 0.0157 18-Aug K.DLIGVQNLLK.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1111.6601 0.92 25469 20558 2 1111.660377 556.8373 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3809.1 - 5.88E+06 - - - 0.2402 - 1.55 0.318 - 158.4 1 2 0 0.0003 10 0 0 0 1.94E+07 2.11E+07 - - - 2.613 1 230117_WJC_METTL3_WT_vs_EV_F03.20560.20560.2 2.81E-13 17/30 R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 11.34 25471 20560 2 1756.906994 879.4608 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3809.2 - 4.88E+06 - - - 0.0205 - 3.636 0.609 - 1126.9 1 2 0 0 16 0 0 0 7.81E+07 6.88E+06 - - - 6.7128 0.9797 230117_WJC_METTL3_WT_vs_EV_F03.20562.20562.2 0.41 22-Nov K.IGLIQFC[160.03]LSAPK.T sp|P50991|TCPD_HUMAN 1 1345.7428 9.43 25473 20562 2 1345.741855 673.8787 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3809.4 - 4.00E+06 - - - -0.6978 - 1.122 0.161 - 152.4 1 2 0 -0.0009 12 0 0 0 1.32E+08 1.40E+07 - - - 0.5327 0.9927 230117_WJC_METTL3_WT_vs_EV_F03.20563.20563.2 1.15 12-Jul K.DLVEWLK.L "sp|Q9P2D1|CHD7_HUMAN,sp|Q14554|PDIA5_HUMAN" 2 901.4909 2.23 25474 20563 2 901.490603 451.7527 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.37 3809.5 - 2.33E+06 - - - -0.3505 - 1.392 0.142 - 198.5 1 2 0 -0.0003 7 0 0 0 6.57E+06 2.95E+06 - - - 1.1377 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.20565.20565.2 0.00211 22-Oct R.VIQELLVDYYVK.L "sp|Q9H6D7|HAUS4_HUMAN,tr|H0YJ09|H0YJ09_HUMAN,tr|G3V4X7|G3V4X7_HUMAN,tr|G3V5A5|G3V5A5_HUMAN,tr|G3V541|G3V541_HUMAN,tr|H0YIZ6|H0YIZ6_HUMAN,tr|G3V5Z2|G3V5Z2_HUMAN" 7 1480.8177 3.35 25476 20565 2 1480.814331 741.4161 HAUS augmin-like complex subunit 4 OS=Homo sapiens OX=9606 GN=HAUS4 PE=1 SV=1 4.37 3809.8 - 1.33E+06 - - - -2.2974 - 2.27 0.442 - 309.8 1 2 0 -0.0034 12 0 0 0 4.21E+06 1.26E+06 - - - 4.4615 0.8583 230117_WJC_METTL3_WT_vs_EV_F03.20566.20566.2 1.69 12-May K.DLVEWLK[136.11].L "sp|Q9P2D1|CHD7_HUMAN,sp|Q14554|PDIA5_HUMAN" 2 909.5051 2.23 25477 20566 2 909.502785 455.7598 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.37 3809.9 - 951844 - - - -2.5662 - 1.145 0.064 - 96.3 1 2 0 -0.0023 7 0 0 0 6.57E+06 2.95E+06 - - - -0.058 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.20568.20568.2 0.00197 22-Oct K.IGLIQFC[160.03]LSAPK[136.11].T sp|P50991|TCPD_HUMAN 1 1353.757 9.43 25479 20568 2 1353.762277 677.8858 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3810.2 - 566242 - - - 3.9025 - 2.205 0.381 - 319.5 1 2 0 0.0053 12 0 0 0 1.32E+08 1.40E+07 - - - 3.9339 1 230117_WJC_METTL3_WT_vs_EV_F03.20571.20571.2 1.05E-06 20-Nov K.YFFFDDGNGLK.G sp|P61009|SPCS3_HUMAN 1 1321.5979 0.8 25482 20571 2 1321.595358 661.8062 Signal peptidase complex subunit 3 OS=Homo sapiens OX=9606 GN=SPCS3 PE=1 SV=1 4.21 3810.6 - 389566 - - - -1.9257 - 1.946 0.578 - 337.5 1 2 0 -0.0025 11 0 0 0 3.11E+06 3.91E+06 - - - 5.1104 1 230117_WJC_METTL3_WT_vs_EV_F03.20575.20575.3 2.05E-09 20/60 R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 9.71 25484 20575 3 1756.906522 586.6429 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3811.1 - 1.64E+07 - - - -0.2482 - 3.417 0.543 - 583.9 1 2 0 -0.0004 16 0 0 0 3.51E+07 3.61E+06 - - - 7.7466 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.20580.20580.2 0.00107 18-Oct K.IMLPWDPTGK.L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1156.5951 1.83 25489 20580 2 1156.592078 579.3048 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3811.4 - 3.56E+06 - - - -2.5834 - 1.603 0.479 - 380.3 1 2 0 -0.003 10 0 0 0 8.65E+07 4.72E+07 - - - 3.8951 1 230117_WJC_METTL3_WT_vs_EV_F03.20581.20581.2 1.39E-08 14/30 R.LMNETTAVALAYGIYK[136.11].Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1764.9212 11.25 25490 20581 2 1764.917492 883.4679 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3811.5 - 2.74E+06 - - - -2.0771 - 3.153 0.598 - 677.6 1 2 0 -0.0037 16 0 0 0 7.74E+07 6.88E+06 - - - 6.28 0.9816 230117_WJC_METTL3_WT_vs_EV_F03.20583.20583.2 0.000161 22-Oct R.GLALALFGGEPK[136.11].N "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1179.6743 2.02 25492 20583 2 1179.667635 590.8444 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 6 3811.8 - 1.59E+06 - - - -5.6583 - 2.136 0.361 - 193.6 1 2 0 -0.0067 12 0 0 0 1.22E+07 6.02E+06 - - - 3.7021 0.9589 230117_WJC_METTL3_WT_vs_EV_F03.20589.20589.2 0.00304 20-Jul R.LLEIDPYLKPY.A sp|Q04446|GLGB_HUMAN 1 1362.7435 6.37 25498 20589 2 1362.745676 682.379 "1,4-alpha-glucan-branching enzyme OS=Homo sapiens OX=9606 GN=GBE1 PE=1 SV=3" 4.37 3812.6 - 736081 - - - 1.5931 - 1.576 0.388 - 152.6 1 1 0 0.0022 11 0 0 0 2.21E+06 3.47E+05 - - - 3.1367 1 230117_WJC_METTL3_WT_vs_EV_F03.20590.20590.2 4.06E-11 15/28 K.LLPLGATDTAVFDVR.L "sp|Q96EY5|MB12A_HUMAN,tr|E9PLL0|E9PLL0_HUMAN,tr|E9PQA6|E9PQA6_HUMAN" 3 1586.8668 -1 25499 20590 2 1586.865228 794.4407 Multivesicular body subunit 12A OS=Homo sapiens OX=9606 GN=MVB12A PE=1 SV=1 4.21 3812.7 - 626770 - - - -0.9957 - 2.646 0.648 - 689.7 1 2 0 -0.0016 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2189 1 230117_WJC_METTL3_WT_vs_EV_F03.20596.20596.2 1.29E-06 14/22 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 -1 25503 20596 2 1603.765759 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3813.4 - 1.87E+08 - - - 1.1342 - 1.949 0.615 - 541.7 1 2 0 0.0018 12 0 0 0 0.00E+00 0.00E+00 - - - 5.3386 1 230117_WJC_METTL3_WT_vs_EV_F03.20598.20598.2 8.04E-05 13/20 K.WYLENVYPELR.V sp|Q10471|GALT2_HUMAN 1 1480.7351 1.02 25505 20598 2 1480.733966 741.3748 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3813.7 - 790817 - - - -0.7422 - 2.372 0.511 - 675.6 1 2 0 -0.0011 11 0 0 0 5.19E+07 5.08E+07 - - - 5.1515 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.20600.20600.2 0.000301 18-Aug R.AFDLFNPNFK.S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1211.5975 1.59 25507 20600 2 1211.594471 606.806 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3813.9 - 443487 - - - -2.5074 - 1.684 0.433 - 161.1 1 2 0 -0.003 10 0 0 0 3.96E+07 2.50E+07 - - - 3.6929 1 230117_WJC_METTL3_WT_vs_EV_F03.20601.20601.3 2.36E-05 20/56 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.3 25508 20601 3 1548.921964 517.3153 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3814.1 - 410212 - - - -1.2686 - 3.372 0.573 - 675 1 2 0 -0.002 15 0 0 0 1.61E+07 1.24E+07 - - - 8.0995 1 230117_WJC_METTL3_WT_vs_EV_F03.20602.20602.2 4.13E-05 18-Nov R.AFDLFNPNFK[136.11].S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1219.6117 1.59 25509 20602 2 1219.610572 610.8131 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3814.2 - 342916 - - - -0.9323 - 2.072 0.556 - 420.5 1 2 0 -0.0011 10 0 0 0 3.96E+07 2.50E+07 - - - 5.1808 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.20603.20603.3 0.000981 18/56 K.LLGASELPIVTPALR[166.11].A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1558.9322 1.3 25510 20603 3 1558.930762 520.6513 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3814.3 - 338908 - - - -0.9218 - 2.733 0.463 - 565.9 1 2 0 -0.0014 15 0 0 0 1.61E+07 1.24E+07 - - - 6.3251 1 230117_WJC_METTL3_WT_vs_EV_F03.20605.20605.2 8.79E-05 15/22 R.VPFLVLEC[160.03]PNLK[136.11].L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1435.7989 1.1 25512 20605 2 1435.794075 718.9067 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3814.6 - 291532 - - - -3.3312 - 2.638 0.493 - 956.6 1 2 0 -0.0048 12 0 0 0 2.46E+07 2.24E+07 - - - 5.2331 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.20608.20608.2 0.00293 22-Sep K.LVGQSIIAYLQK.K "sp|P53621|COPA_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 3 1331.7813 0.69 25515 20608 2 1331.779913 666.8979 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 8.59 3815 - 234991 - - - -1.0317 - 1.791 0.383 - 139.5 1 2 0 -0.0014 12 0 0 0 6.09E+06 8.87E+06 - - - 3.4028 0.8931 230117_WJC_METTL3_WT_vs_EV_F03.20609.20609.2 9.35 22-Aug K.EALQLMATYLPK[136.11].D "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 13 1384.7516 2.17 25516 20609 2 1384.755541 693.3831 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 6.1 3815.1 - 213234 - - - 2.8648 - 1.033 0.042 - 67.7 3 2 0 0.004 12 0 0 0 7.58E+07 3.50E+07 - - - -0.7777 0.9427 230117_WJC_METTL3_WT_vs_EV_F03.20615.20615.2 0.525 12-Aug R.EIALWFR[166.11].A "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 943.5155 1.19 25522 20615 2 943.510782 472.765 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6.1 3815.9 - 90509.6 - - - -5.0089 - 1.591 0.177 - 286.8 1 2 0 -0.0047 7 0 0 0 1.19E+07 1.00E+07 - - - 1.8182 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20619.20619.2 6.49E-06 18-Oct K.IMLPWDPTGK[136.11].L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1164.6093 1.83 25525 20619 2 1164.608682 583.3119 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3816.4 - 8.81E+06 - - - -0.5015 - 1.839 0.486 - 387.9 1 2 0 -0.0006 10 0 0 0 8.65E+07 4.72E+07 - - - 4.3309 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.20621.20621.2 0.0379 14-Jul K.FGFYEVFK[136.11].V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1043.5208 1 25527 20621 2 1043.521193 522.7677 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3816.5 - 6.64E+06 - - - 0.4063 - 1.523 0.362 - 103.4 1 2 0 0.0004 8 0 0 0 5.22E+07 5.24E+07 - - - 2.9834 1 230117_WJC_METTL3_WT_vs_EV_F03.20622.20622.2 3.97E-06 22-Nov K.GIDPFSLDALSK[136.11].E sp|P40227|TCPZ_HUMAN 1 1269.6696 9.64 25528 20622 2 1269.670082 635.8421 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3816.5 - 5.86E+06 - - - 0.3654 - 2.372 0.544 - 361.9 1 2 0 0.0005 12 0 0 0 7.89E+08 8.19E+07 - - - 5.3315 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20623.20623.2 0.00763 14-Sep K.FGFYEVFK.V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1035.5066 1 25529 20623 2 1035.508158 518.7606 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3816.6 - 5.32E+06 - - - 1.5345 - 1.718 0.394 - 186.3 1 2 0 0.0016 8 0 0 0 5.22E+07 5.24E+07 - - - 3.5827 0.9924 230117_WJC_METTL3_WT_vs_EV_F03.20624.20624.2 0.0826 12-Jul R.EIALWFR.A "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 933.5072 1.19 25530 20624 2 933.50519 467.7609 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6.1 3816.7 - 4.90E+06 - - - -2.1939 - 1.472 0.25 - 245.4 1 2 0 -0.002 7 0 0 0 1.19E+07 1.00E+07 - - - 2.1119 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.20625.20625.2 3.33E-05 22-Dec R.VPFLVLEC[160.03]PNLK.L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1427.7847 1.1 25531 20625 2 1427.783045 714.8996 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3816.7 - 4.59E+06 - - - -1.1297 - 2.526 0.416 - 630 1 2 0 -0.0016 12 0 0 0 2.46E+07 2.24E+07 - - - 4.5512 0.9883 230117_WJC_METTL3_WT_vs_EV_F03.20629.20629.2 0.415 16-Aug R.NALDLLLPK[136.11].L "sp|P30566|PUR8_HUMAN,tr|A0A096LNY5|A0A096LNY5_HUMAN,tr|A0A1B0GTJ7|A0A1B0GTJ7_HUMAN,tr|A0A1B0GWJ0|A0A1B0GWJ0_HUMAN,tr|A0A1B0GWF8|A0A1B0GWF8_HUMAN,tr|A0A096LNY4|A0A096LNY4_HUMAN,tr|A0A1B0GTG9|A0A1B0GTG9_HUMAN,tr|A0A7P0T9A7|A0A7P0T9A7_HUMAN,tr|A0A096LNY6|A0A096LNY6_HUMAN,tr|A0A096LP92|A0A096LP92_HUMAN,tr|A0A7P0Z472|A0A7P0Z472_HUMAN" 11 1003.6157 1.32 25535 20629 2 1003.615048 502.8151 Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2 5.84 3817 - 1.64E+06 - - - -0.6815 - 1.459 0.108 - 153.9 1 2 0 -0.0007 9 0 0 0 1.56E+07 1.18E+07 - - - 0.9313 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.20631.20631.2 0.00681 14-Aug R.ETILNLLR[166.11].K "sp|Q6P158|DHX57_HUMAN,tr|A0A087WZ11|A0A087WZ11_HUMAN" 2 980.5894 0.92 25537 20631 2 980.587182 491.302 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 6.1 3817.2 - 883379 - - - -2.2629 - 1.98 0.354 - 228.3 1 2 0 -0.0022 8 0 0 0 7.19E+06 7.80E+06 - - - 3.7151 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20633.20633.2 2.21E-05 20-Aug K.WYLENVYPELR[166.11].V sp|Q10471|GALT2_HUMAN 1 1490.7433 1.02 25538 20633 2 1490.743833 746.3789 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3817.4 - 8.43E+06 - - - 0.3341 - 1.75 0.483 - 236.4 1 2 0 0.0005 11 0 0 0 5.18E+07 5.08E+07 - - - 4.1222 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20635.20635.2 0.00162 18-Sep R.LGGIAYFLSR[166.11].L "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1105.616 1.01 25539 20635 2 1105.615928 553.8153 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 8.75 3817.6 - 1.01E+06 - - - -0.0199 - 1.964 0.399 - 253.2 1 2 0 0 10 0 0 0 2.72E+07 2.68E+07 - - - 3.8721 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20636.20636.2 0.0047 18-Nov K.ILDVLEEIPK[136.11].N "sp|Q16718|NDUA5_HUMAN,tr|C9IZN5|C9IZN5_HUMAN,tr|H7BYD0|H7BYD0_HUMAN,tr|A0A087X1G1|A0A087X1G1_HUMAN,tr|F8WAS3|F8WAS3_HUMAN,tr|A0A7I2V2W4|A0A7I2V2W4_HUMAN,tr|A0A7I2V3L8|A0A7I2V3L8_HUMAN" 7 1175.6893 2.26 25540 20636 2 1175.688967 588.8519 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3 4.14 3817.7 - 567981 - - - -0.2756 - 2.151 0.271 - 244.7 1 2 0 -0.0003 10 0 0 0 9.84E+07 4.35E+07 - - - 3.1805 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.20639.20639.2 8.04E-06 20-Nov K.IFGVTTLDIVR.A "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1232.7129 1.32 25543 20639 2 1232.713633 617.3637 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 5.84 3817.9 - 1.06E+06 - - - 0.6165 - 2.218 0.397 - 456.7 1 2 0 0.0008 11 0 0 0 5.29E+07 4.01E+07 - - - 4.128 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.20643.20643.2 0.255 16-Nov K.TEILPPFFK[136.11].H sp|O75533|SF3B1_HUMAN 1 1098.6205 1 25545 20643 2 1098.618214 550.3175 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.66 3818.4 - 4.04E+06 - - - -2.0653 - 1.993 0.334 - 504.9 1 2 0 -0.0023 9 0 0 0 6.45E+07 6.44E+07 - - - 3.5024 0.9977 230117_WJC_METTL3_WT_vs_EV_F03.20644.20644.2 0.0042 16-Sep K.TEILPPFFK.H sp|O75533|SF3B1_HUMAN 1 1090.6063 1 25546 20644 2 1090.603983 546.3104 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.66 3818.4 - 3.38E+06 - - - -2.1089 - 1.685 0.4 - 326.5 1 2 0 -0.0023 9 0 0 0 6.45E+07 6.44E+07 - - - 3.5042 1 230117_WJC_METTL3_WT_vs_EV_F03.20646.20646.2 5.66E-07 16-Sep R.FYNLVLLPR[166.11].V "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1143.668 1.03 25548 20646 2 1143.667423 572.8413 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 3818.6 - 3.54E+06 - - - -0.4923 - 2.009 0.583 - 350.1 1 2 0 -0.0006 9 0 0 0 5.53E+07 5.35E+07 - - - 5.3652 1 230117_WJC_METTL3_WT_vs_EV_F03.20647.20647.2 3.18E-05 16-Nov R.FYNLVLLPR.V "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1133.6597 1.03 25549 20647 2 1133.658653 567.8371 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 3818.7 - 3.25E+06 - - - -0.9377 - 2.128 0.52 - 497.5 1 2 0 -0.0011 9 0 0 0 5.53E+07 5.35E+07 - - - 5.0662 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20648.20648.2 0.00152 20-Oct K.FLFVDADQIVR.T sp|Q9NYU2|UGGG1_HUMAN 1 1321.703 9.06 25550 20648 2 1321.702338 661.8588 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.21 3818.8 - 3.15E+06 - - - -0.5289 - 1.961 0.427 - 266.2 1 2 0 -0.0007 11 0 0 0 8.08E+07 8.92E+06 - - - 4.0165 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20649.20649.2 4.02E-06 18-Nov K.FSDFLLDPYK[136.11].Y sp|Q9UIG0|BAZ1B_HUMAN 1 1251.6267 0.84 25551 20649 2 1251.629593 626.8206 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 4.21 3818.9 - 1.88E+06 - - - 2.3186 - 2.296 0.303 - 304.6 1 2 0 0.0029 10 0 0 0 1.54E+07 1.82E+07 - - - 3.5981 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20650.20650.2 0.000189 13/20 R.NTISLLVAGLK.K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1127.6914 1.63 25552 20650 2 1127.690731 564.853 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.75 3819 - 1.85E+06 - - - -0.6021 - 2.381 0.416 - 602.8 1 2 0 -0.0007 11 0 0 0 2.32E+07 1.43E+07 - - - 4.4602 1 230117_WJC_METTL3_WT_vs_EV_F03.20651.20651.2 4.00E-07 15/22 R.VPDGMVGLIIGR.G "sp|Q92945|FUBP2_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 1225.6853 2.32 25553 20651 2 1225.688969 613.8499 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.81 3819.1 - 1.64E+06 - - - 3.0114 - 2.524 0.651 - 985 1 2 0 0.0037 12 0 0 0 3.68E+07 1.59E+07 - - - 6.2842 0.9949 230117_WJC_METTL3_WT_vs_EV_F03.20655.20655.2 0.000349 18-Dec K.YSDIDIILLK[136.11].G "sp|Q92973|TNPO1_HUMAN,tr|A0A7P0T9C0|A0A7P0T9C0_HUMAN,tr|A0A7P0TBF0|A0A7P0TBF0_HUMAN,tr|A0A7P0T944|A0A7P0T944_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 5 1199.6893 1.07 25557 20655 2 1199.684538 600.8519 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 4.21 3819.6 - 837391 - - - -3.9619 - 1.885 0.46 - 276.6 1 2 0 -0.0048 10 0 0 0 1.67E+07 1.56E+07 - - - 4.2066 1 230117_WJC_METTL3_WT_vs_EV_F03.20656.20656.2 1.82E-06 14/24 K.ILGVWDTAVSLGK.L sp|Q53RT3|APRV1_HUMAN 1 1357.7606 999 25558 20656 2 1357.75827 679.8876 Retroviral-like aspartic protease 1 OS=Homo sapiens OX=9606 GN=ASPRV1 PE=1 SV=1 5.84 3819.8 - 821899 - - - -1.6807 - 2.706 0.556 - 632.1 1 2 0 -0.0023 13 0 0 0 3.03E+07 0.00E+00 - - - 5.7018 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.20659.20659.2 0.0072 16-Aug R.QVLLEIFSK.N "sp|Q9NVU0|RPC5_HUMAN,tr|A0A0C4DH01|A0A0C4DH01_HUMAN" 2 1075.6277 1.81 25561 20659 2 1075.626593 538.8211 DNA-directed RNA polymerase III subunit RPC5 OS=Homo sapiens OX=9606 GN=POLR3E PE=1 SV=1 6 3820.1 - 592428 - - - -1.0729 - 1.621 0.376 - 124.7 1 2 0 -0.0012 9 0 0 0 5.43E+06 3.01E+06 - - - 3.2152 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20666.20666.2 0.00511 28-Jul K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 1170.6 25567 20666 2 1658.907814 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3821 - 1.45E+07 - - - -0.7553 - 1.822 0.428 - 115 1 2 0 -0.0013 15 0 0 0 3.39E+08 2.90E+05 - - - 3.6768 0.9602 230117_WJC_METTL3_WT_vs_EV_F03.20669.20669.2 0.796 22-Jun R.FLPEFPSC[160.03]SLLK.E sp|Q9H9A6|LRC40_HUMAN 1 1436.7374 2.43 25570 20669 2 1436.733867 719.376 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.99 3821.1 - 2.78E+06 - - - -2.4409 - 1.169 0.187 - 64.1 1 2 0 -0.0035 12 0 0 0 2.12E+07 8.73E+06 - - - 0.8319 0.8506 230117_WJC_METTL3_WT_vs_EV_F03.20670.20670.2 0.0123 20-Sep K.LTPLILKPFGN.S "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1211.7278 0.79 25571 20670 2 1211.726368 606.8712 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 8.75 3821.2 - 2.56E+06 - - - -1.1777 - 1.485 0.356 - 235.7 1 1 0 -0.0014 11 0 0 0 1.99E+07 2.53E+07 - - - 2.7397 1 230117_WJC_METTL3_WT_vs_EV_F03.20671.20671.2 1.15E-07 17/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 25572 20671 2 1343.614802 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3821.3 - 2.47E+06 - - - 2.4858 - 2.994 0.54 - 1130.3 1 1 0 0.0033 10 0 0 0 3.40E+07 0.00E+00 - - - 6.0894 1 230117_WJC_METTL3_WT_vs_EV_F03.20672.20672.2 1.87E-07 26-Dec K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.15 25573 20672 2 1416.842227 709.4289 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3821.4 - 1.63E+06 - - - -0.6627 - 2.588 0.581 - 523.7 1 2 0 -0.0009 14 0 0 0 1.33E+08 1.16E+08 - - - 5.7182 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20673.20673.2 0.000466 22-Sep R.YGLFPANYVELR[166.11].Q sp|Q14247|SRC8_HUMAN 1 1450.7484 1.65 25574 20673 2 1450.748568 726.3815 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 6 3821.6 - 1.21E+06 - - - 0.1013 - 1.899 0.489 - 197.8 1 2 0 0.0001 12 0 0 0 1.24E+07 7.50E+06 - - - 4.3401 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.20675.20675.3 0.000447 14/56 R.NIETIINTFHQYSVK.L sp|P06702|S10A9_HUMAN 1 1805.9312 4.94 25576 20675 3 1805.936309 602.9843 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 3821.8 - 940639 - - - 2.8296 - 2.307 0.409 - 172.3 1 2 0 0.0051 15 0 0 0 3.27E+06 6.62E+05 - - - 5.2798 1 230117_WJC_METTL3_WT_vs_EV_F03.20678.20678.3 2.15E-09 14/56 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 438.37 25577 20678 3 1658.91072 553.977 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3822.2 - 1.25E+06 - - - 0.9964 - 3.001 0.521 - 305.8 1 2 0 0.0017 15 0 0 0 2.57E+08 5.87E+05 - - - 7.2157 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20679.20679.2 0.00185 20-Aug K.LFTAESLIGLK.N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1190.6911 1.69 25578 20679 2 1190.692073 596.3528 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6 3822.2 - 325634 - - - 0.8382 - 1.635 0.424 - 167.6 1 2 0 0.001 11 0 0 0 7.06E+07 4.19E+07 - - - 3.5024 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.20680.20680.2 0.00737 16-Jul R.GFAFVYFER[166.11].L sp|Q13595|TRA2A_HUMAN 1 1144.5581 0.84 25579 20680 2 1144.559626 573.2863 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3822.3 - 919655 - - - 1.3324 - 1.198 0.295 - 134.8 1 2 0 0.0015 9 0 0 0 2.87E+07 3.40E+07 - - - 1.742 0.999 230117_WJC_METTL3_WT_vs_EV_F03.20681.20681.2 0.0812 16-Sep R.GFAFVYFER.L sp|Q13595|TRA2A_HUMAN 1 1134.5498 0.84 25580 20681 2 1134.551676 568.2822 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3822.4 - 753764 - - - 1.6262 - 1.333 0.344 - 248.5 1 2 0 0.0018 9 0 0 0 2.87E+07 3.40E+07 - - - 2.4128 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.20687.20687.2 0.0496 22-Dec R.LTVLLPLAAAER[166.11].D sp|Q8IZ52|CHSS2_HUMAN 1 1275.779 0.84 25586 20687 2 1275.776702 638.8968 Chondroitin sulfate synthase 2 OS=Homo sapiens OX=9606 GN=CHPF PE=1 SV=2 6 3823.1 - 75785.1 - - - -1.7958 - 2.344 0.27 - 341.3 1 2 0 -0.0023 12 0 0 0 4.39E+06 5.21E+06 - - - 3.2759 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.20690.20690.2 0.00668 20-Nov K.LFTAESLIGLK[136.11].N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1198.7053 1.69 25587 20690 2 1198.704228 600.3599 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6 3823.5 - 1.17E+06 - - - -0.8734 - 2.182 0.393 - 355 1 2 0 -0.001 11 0 0 0 7.06E+07 4.19E+07 - - - 4.0541 1 230117_WJC_METTL3_WT_vs_EV_F03.20691.20691.2 1.81E-08 14/26 K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.15 25588 20691 2 1408.827423 705.4218 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3823.5 - 853951 - - - -1.0952 - 2.856 0.507 - 783.6 1 2 0 -0.0015 14 0 0 0 1.33E+08 1.16E+08 - - - 5.4187 1 230117_WJC_METTL3_WT_vs_EV_F03.20693.20693.2 1.67E-05 14/22 K.ALLVEVQLLESK.T sp|O00231|PSD11_HUMAN 1 1340.7915 2.03 25590 20693 2 1340.794079 671.403 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.53 3823.8 - 654201 - - - 1.9101 - 2.825 0.464 - 702.7 1 2 0 0.0026 12 0 0 0 1.19E+07 5.83E+06 - - - 5.1998 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.20694.20694.2 0.000529 18-Oct K.MPLIGLGTWK[136.11].S "sp|P14550|AK1A1_HUMAN,sp|P15121|ALDR_HUMAN,tr|V9GYG2|V9GYG2_HUMAN,tr|E9PCX2|E9PCX2_HUMAN,tr|Q5T621|Q5T621_HUMAN,tr|V9GYP9|V9GYP9_HUMAN,tr|E9PEF9|E9PEF9_HUMAN" 7 1122.6351 0.72 25591 20694 2 1122.639753 562.3248 Aldo-keto reductase family 1 member A1 OS=Homo sapiens OX=9606 GN=AKR1A1 PE=1 SV=3 8.5 3823.9 - 409662 - - - 4.1563 - 2.134 0.416 - 315.7 1 2 0 0.0047 10 0 0 0 7.08E+06 9.87E+06 - - - 4.2279 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20696.20696.2 0.00205 22-Nov K.ALLVEVQLLESK[136.11].T sp|O00231|PSD11_HUMAN 1 1348.8057 2.03 25593 20696 2 1348.809983 675.4101 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.53 3824.1 - 278011 - - - 3.1621 - 2.382 0.289 - 411.5 1 2 0 0.0043 12 0 0 0 1.19E+07 5.83E+06 - - - 3.4579 0.9918 230117_WJC_METTL3_WT_vs_EV_F03.20697.20697.2 0.0861 12-Jun K.YPVWLWK.R "sp|Q13084|RM28_HUMAN,tr|A2IDC6|A2IDC6_HUMAN,tr|A2IDC7|A2IDC7_HUMAN,tr|Q4TT37|Q4TT37_HUMAN" 4 990.5327 0.4 25594 20697 2 990.531304 496.2736 "39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4" 8.59 3824.3 - 276291 - - - -1.4336 - 1.195 0.27 - 112.1 1 2 0 -0.0014 7 0 0 0 3.44E+06 8.63E+06 - - - 1.5992 1 230117_WJC_METTL3_WT_vs_EV_F03.20701.20701.3 5.94E-07 14/52 K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.25 25598 20701 3 1416.845232 473.2883 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3824.8 - 147327 - - - 1.4582 - 3.134 0.485 - 232.9 1 2 0 0.0021 14 0 0 0 1.98E+07 1.58E+07 - - - 6.9824 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.20702.20702.2 0.000649 14-Jul K.ETLLAMFK[136.11].Y sp|P26639|SYTC_HUMAN 1 959.5241 1.92 25599 20702 2 959.52341 480.7693 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 6.1 3824.9 - 117782 - - - -0.7608 - 1.594 0.391 - 116.3 1 2 0 -0.0007 8 0 0 0 3.19E+06 1.66E+06 - - - 3.3349 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.20703.20703.2 0.00095 30-Nov K.LPPPLSAPVAGLAALK.A sp|Q14781|CBX2_HUMAN 1 1513.9232 2 25600 20703 2 1513.920198 757.9689 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.75 3825.1 - 0 - - - -1.9836 - 1.937 0.44 - 241.9 1 2 0 -0.003 16 0 0 0 4.32E+06 2.15E+06 - - - 3.9153 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.20707.20707.2 0.000748 16-Aug R.GVVELLLAR.K sp|P57078|RIPK4_HUMAN 1 968.6019 -1 25604 20707 2 968.601289 485.3082 Receptor-interacting serine\threonine-protein kinase 4 OS=Homo sapiens OX=9606 GN=RIPK4 PE=1 SV=1 6 3825.6 - 96925.5 - - - -0.5957 - 1.899 0.387 - 169.2 1 2 0 -0.0006 9 0 0 0 0.00E+00 0.00E+00 - - - 3.7546 1 230117_WJC_METTL3_WT_vs_EV_F03.20711.20711.2 0.000133 16-Oct R.YLTVAAIFR.G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1052.6019 2.77 25607 20711 2 1052.602074 527.3082 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3826.2 - 3.43E+06 - - - 0.1976 - 1.901 0.519 - 358.4 1 2 0 0.0002 9 0 0 0 1.53E+07 5.54E+06 - - - 4.7327 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.20712.20712.2 0.0448 14-Aug R.VIFGLFGK[136.11].T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 887.536 0.53 25608 20712 2 887.535162 444.7753 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.72 3826.3 - 3.02E+06 - - - -0.9724 - 1.592 0.338 - 199.2 1 2 0 -0.0009 8 0 0 0 1.10E+07 2.07E+07 - - - 2.9396 1 230117_WJC_METTL3_WT_vs_EV_F03.20713.20713.3 4.56E-05 21/52 K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.25 25609 20713 3 1408.828005 470.6169 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3826.4 - 1.56E+06 - - - -0.6821 - 3.235 0.546 - 625.9 1 2 0 -0.001 14 0 0 0 1.98E+07 1.58E+07 - - - 7.7471 1 230117_WJC_METTL3_WT_vs_EV_F03.20714.20714.2 8.24E-09 21/34 K.ILDSFAAAPVPTTTLVLK.S sp|P18583|SON_HUMAN 1 1856.0659 1.4 25610 20714 2 1856.062566 929.0402 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3826.5 - 1.42E+06 - - - -1.7973 - 3.538 0.608 - 956.3 1 2 0 -0.0033 18 0 0 0 1.52E+07 1.09E+07 - - - 6.6372 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.20715.20715.2 0.000262 18-Nov K.MPLIGLGTWK.S "sp|P14550|AK1A1_HUMAN,sp|P15121|ALDR_HUMAN,tr|V9GYG2|V9GYG2_HUMAN,tr|E9PCX2|E9PCX2_HUMAN,tr|Q5T621|Q5T621_HUMAN,tr|V9GYP9|V9GYP9_HUMAN,tr|E9PEF9|E9PEF9_HUMAN" 7 1114.6209 0.53 25611 20715 2 1114.619596 558.3177 Aldo-keto reductase family 1 member A1 OS=Homo sapiens OX=9606 GN=AKR1A1 PE=1 SV=3 8.5 3826.6 - 2.05E+06 - - - -1.1582 - 1.786 0.224 - 244.5 1 2 0 -0.0013 10 0 0 0 9.14E+06 1.73E+07 - - - 2.314 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.20716.20716.2 0.108 14-Jun R.VIFGLFGK.T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 879.5218 0.53 25612 20716 2 879.520758 440.7682 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.72 3826.8 - 1.31E+06 - - - -1.2132 - 1.339 0.343 - 120.5 1 2 0 -0.0011 8 0 0 0 1.10E+07 2.07E+07 - - - 2.4545 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.20717.20717.2 0.00502 16-Sep R.YLTVAAIFR[166.11].G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1062.6101 2.83 25613 20717 2 1062.611721 532.3123 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3826.9 - 1.14E+06 - - - 1.4916 - 2.065 0.439 - 281.3 1 2 0 0.0016 9 0 0 0 1.58E+07 5.58E+06 - - - 4.3808 1 230117_WJC_METTL3_WT_vs_EV_F03.20718.20718.2 1.01E-08 15/34 K.ILDSFAAAPVPTTTLVLK[136.11].S sp|P18583|SON_HUMAN 1 1864.0801 1.4 25614 20718 2 1864.076489 933.0473 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3827 - 986222 - - - -1.9382 - 3.147 0.549 - 362.4 1 2 0 -0.0036 18 0 0 0 1.52E+07 1.09E+07 - - - 5.9134 1 230117_WJC_METTL3_WT_vs_EV_F03.20723.20723.2 5.27E-06 20-Oct R.GGYFDEFGIIR.D "sp|P11413|G6PD_HUMAN,tr|E7EM57|E7EM57_HUMAN,tr|E7EUI8|E7EUI8_HUMAN" 3 1272.6139 -1 25619 20723 2 1272.614614 637.3142 Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4 4.37 3827.7 - 476066 - - - 0.5705 - 1.899 0.596 - 231.3 1 2 0 0.0007 11 0 0 0 0.00E+00 0.00E+00 - - - 5.1778 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.20724.20724.2 0.00125 14-Jun K.ETLLAMFK.Y sp|P26639|SYTC_HUMAN 1 951.5099 1.92 25620 20724 2 951.509547 476.7622 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 6.1 3827.8 - 467046 - - - -0.413 - 1.181 0.399 - 109.3 1 2 0 -0.0004 8 0 0 0 3.19E+06 1.66E+06 - - - 2.4896 0.9152 230117_WJC_METTL3_WT_vs_EV_F03.20727.20727.2 0.0533 22-Jul K.LFISGLPFSC[160.03]TK.E "sp|Q15020|SART3_HUMAN,tr|H0YHU8|H0YHU8_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 3 1368.7112 7.39 25623 20727 2 1368.709523 685.3629 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 8.22 3828.2 - 344991 - - - -1.1953 - 1.225 0.024 - 87.2 1 2 0 -0.0016 12 0 0 0 4.87E+06 6.58E+05 - - - -0.2483 1 230117_WJC_METTL3_WT_vs_EV_F03.20728.20728.2 1.24E-08 13/26 K.ELIELTEASLVSVR.K "sp|Q8N5A5|ZGPAT_HUMAN,tr|X6RGY1|X6RGY1_HUMAN" 2 1557.8614 1.33 25624 20728 2 1557.867151 779.938 Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3 4.25 3828.3 - 328750 - - - 3.6993 - 3.182 0.592 - 560.5 1 2 0 0.0058 14 0 0 0 2.87E+06 2.16E+06 - - - 6.3164 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20730.20730.2 0.000276 20-Sep K.ILLTQENPFFR.K sp|Q08J23|NSUN2_HUMAN 1 1376.7452 2.13 25625 20730 2 1376.744591 689.3799 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3828.5 - 2.51E+06 - - - -0.4685 - 1.922 0.469 - 322.4 1 2 0 -0.0006 11 0 0 0 8.49E+07 3.99E+07 - - - 4.2723 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20733.20733.2 0.02 16-Sep K.IGFPWSEIR[166.11].N "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 1113.5847 0.93 25628 20733 2 1113.585304 557.7996 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 6 3828.8 - 5.03E+06 - - - 0.5873 - 1.551 0.399 - 206.2 1 2 0 0.0007 9 0 0 0 8.69E+06 9.35E+06 - - - 3.2576 0.9711 230117_WJC_METTL3_WT_vs_EV_F03.20734.20734.2 0.644 20-Apr K.THGSEYYEC[160.03]SR[166.11].Y sp|O95376|ARI2_HUMAN 1 1397.5545 0.001 25629 20734 2 1397.556692 699.7846 E3 ubiquitin-protein ligase ARIH2 OS=Homo sapiens OX=9606 GN=ARIH2 PE=1 SV=1 5.37 3828.9 - 2.99E+06 - - - 1.5334 - 0.753 0.202 - 23.4 1 2 0 0.0021 11 0 0 0 0.00E+00 5.46E+06 - - - -0.2351 0.9933 230117_WJC_METTL3_WT_vs_EV_F03.20740.20740.2 0.0129 26-Sep R.LFLVGSSLNGFGTR.S "sp|Q6PIY7|GLD2_HUMAN,tr|D6RAF2|D6RAF2_HUMAN" 2 1466.7882 -1 25635 20740 2 1466.781972 734.4014 Poly(A) RNA polymerase GLD2 OS=Homo sapiens OX=9606 GN=TENT2 PE=1 SV=1 9.75 3829.4 - 1.28E+06 - - - -4.2215 - 2.134 0.404 - 146.1 1 2 0 -0.0062 14 0 0 0 0.00E+00 0.00E+00 - - - 3.9252 1 230117_WJC_METTL3_WT_vs_EV_F03.20742.20742.2 1.12E-06 24-Dec K.MVFINNIALAQIK[136.11].N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1481.852 1.13 25637 20742 2 1481.850858 741.9333 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3829.6 - 1.00E+06 - - - -0.741 - 2.696 0.544 - 447.6 1 2 0 -0.0011 13 0 0 0 1.37E+07 1.21E+07 - - - 5.604 1 230117_WJC_METTL3_WT_vs_EV_F03.20743.20743.2 1.71E-07 14/24 K.MVFINNIALAQIK.N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1473.8378 1.13 25638 20743 2 1473.838794 737.9262 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3829.8 - 954493 - - - 0.7043 - 2.716 0.582 - 559.8 1 2 0 0.001 13 0 0 0 1.37E+07 1.21E+07 - - - 5.9037 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20744.20744.2 0.00211 26-Oct K.VLFLLGADGGC[160.03]ITR.Q "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1490.7915 1.56 25639 20744 2 1490.791033 746.403 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 5.8 3829.9 - 893417 - - - -0.3367 - 2.104 0.492 - 286.2 1 2 0 -0.0005 14 0 0 0 1.73E+06 1.10E+06 - - - 4.5414 1 230117_WJC_METTL3_WT_vs_EV_F03.20745.20745.2 3.86E-06 24-Oct R.ILFIGGITAPTVR.Q sp|P48651|PTSS1_HUMAN 1 1356.8129 -1 25640 20745 2 1356.808163 679.4137 Phosphatidylserine synthase 1 OS=Homo sapiens OX=9606 GN=PTDSS1 PE=1 SV=1 9.75 3830 - 889956 - - - -3.5075 - 2.43 0.496 - 264.7 1 2 0 -0.0048 13 0 0 0 0.00E+00 0.00E+00 - - - 4.9818 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.20746.20746.2 0.0804 14-Sep K.LLELLWNK[136.11].Y "sp|Q92905|CSN5_HUMAN,tr|E5RHH5|E5RHH5_HUMAN" 2 1035.6208 1.44 25641 20746 2 1035.622895 518.8177 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 6 3830.2 - 848786 - - - 2.0065 - 1.859 0.254 - 206.3 1 2 0 0.0021 8 0 0 0 2.35E+06 1.63E+06 - - - 2.7864 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20747.20747.2 1.55E-06 24-Dec R.ILFIGGITAPTVR[166.11].Q sp|P48651|PTSS1_HUMAN 1 1366.8212 -1 25642 20747 2 1366.821569 684.4179 Phosphatidylserine synthase 1 OS=Homo sapiens OX=9606 GN=PTDSS1 PE=1 SV=1 9.75 3830.3 - 828066 - - - 0.2758 - 2.306 0.384 - 447.1 1 2 0 0.0004 13 0 0 0 0.00E+00 0.00E+00 - - - 4.0215 1 230117_WJC_METTL3_WT_vs_EV_F03.20748.20748.3 1.21E-07 17/60 R.TPEQVAEEEYLLQELR[166.11].K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1955.9716 -1 25643 20748 3 1955.971321 652.9978 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3830.4 - 754060 - - - -0.1207 - 2.882 0.593 - 366.6 1 2 0 -0.0002 16 0 0 0 0.00E+00 0.00E+00 - - - 7.8672 0.9722 230117_WJC_METTL3_WT_vs_EV_F03.20751.20751.2 0.0514 22-Jun K.GIDPFSLDALSK.E sp|P40227|TCPZ_HUMAN 1 1261.6554 -1 25645 20751 2 1261.653926 631.835 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3830.9 - 102603 - - - -1.1826 - 1.287 0.176 - 64.7 12 2 0 -0.0015 12 0 0 0 0.00E+00 0.00E+00 - - - 0.5223 0.9965 230117_WJC_METTL3_WT_vs_EV_F03.20752.20752.2 0.0837 20-Jul R.GGYFDEFGIIR[166.11].D "sp|P11413|G6PD_HUMAN,tr|E7EM57|E7EM57_HUMAN,tr|E7EUI8|E7EUI8_HUMAN" 3 1282.6222 2.26 25646 20752 2 1282.62402 642.3184 Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4 4.37 3831.1 - 77542 - - - 1.4517 - 1.158 0.246 - 72.4 1 2 0 0.0019 11 0 0 0 3.19E+06 1.41E+06 - - - 1.2542 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20762.20762.2 0.00504 16-Oct K.IIAATFLFK.W sp|Q13907|IDI1_HUMAN 1 1022.6165 6.19 25656 20762 2 1022.617831 512.3155 Isopentenyl-diphosphate Delta-isomerase 1 OS=Homo sapiens OX=9606 GN=IDI1 PE=1 SV=2 8.75 3832.3 - 276828 - - - 1.3465 - 1.868 0.287 - 215.8 1 2 0 0.0014 9 0 0 0 2.83E+06 4.57E+05 - - - 2.9681 1 230117_WJC_METTL3_WT_vs_EV_F03.20765.20765.2 0.00021 18-Oct R.QALTDFLLAR[166.11].K "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1156.648 1.33 25659 20765 2 1156.644443 579.3313 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.84 3832.7 - 96554.4 - - - -3.0562 - 2.405 0.461 - 351.6 1 2 0 -0.0035 10 0 0 0 2.76E+06 2.07E+06 - - - 4.8943 1 230117_WJC_METTL3_WT_vs_EV_F03.20767.20767.2 0.000864 13/22 R.LALFNPDVC[160.03]WDR.N sp|O00483|NDUA4_HUMAN 1 1504.7133 3.14 25661 20767 2 1504.71111 753.3639 Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1 4.21 3832.9 - 73048.9 - - - -1.4448 - 2.653 0.419 - 616.5 1 2 0 -0.0022 12 0 0 0 7.89E+06 2.51E+06 - - - 4.7023 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20768.20768.2 0.0377 12-Jun K.LNIWDWK.T sp|O60508|PRP17_HUMAN 1 973.5022 2.04 25662 20768 2 973.50362 487.7584 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.84 3833.1 - 72782.2 - - - 1.508 - 1.439 0.309 - 107.3 1 2 0 0.0015 7 0 0 0 2.34E+06 1.15E+06 - - - 2.476 1 230117_WJC_METTL3_WT_vs_EV_F03.20769.20769.2 9.63E-11 15/30 R.TPEQVAEEEYLLQELR.K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1945.9633 -1 25663 20769 2 1945.968229 973.9889 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3833.2 - 48711.6 - - - 2.5396 - 3.679 0.637 - 710.3 1 2 0 0.0049 16 0 0 0 0.00E+00 0.00E+00 - - - 6.9469 1 230117_WJC_METTL3_WT_vs_EV_F03.20774.20774.2 4.75E-07 24-Sep K.VLGTAFDPFLGGK.N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1320.7078 8.83 25667 20774 2 1320.709232 661.3612 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3833.7 - 1.77E+06 - - - 1.0934 - 2.045 0.587 - 183.9 1 2 0 0.0014 13 0 0 0 3.98E+08 4.51E+07 - - - 5.2122 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20780.20780.2 0.0344 14-Oct K.EALLELLR[166.11].L sp|Q13895|BYST_HUMAN 1 965.5785 1.12 25671 20780 2 965.577904 483.7965 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3834.3 - 4.65E+06 - - - -0.6193 - 2.015 0.335 - 391.7 2 2 0 -0.0006 8 0 0 0 4.56E+07 4.08E+07 - - - 3.4937 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20781.20781.2 0.00569 14-Sep K.EALLELLR.L sp|Q13895|BYST_HUMAN 1 955.5702 1.12 25672 20781 2 955.569702 478.7924 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3834.4 - 4.59E+06 - - - -0.5546 - 1.977 0.411 - 330.9 1 2 0 -0.0005 8 0 0 0 4.56E+07 4.08E+07 - - - 4.1321 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.20783.20783.2 0.00158 13/20 K.ELGIWEPLAVK[136.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1261.7162 10.04 25674 20783 2 1261.71428 631.8654 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3834.6 - 3.36E+06 - - - -1.5011 - 2.107 0.326 - 633 1 2 0 -0.0019 11 0 0 0 1.08E+09 1.08E+08 - - - 3.4644 1 230117_WJC_METTL3_WT_vs_EV_F03.20784.20784.2 1.27E-05 14/26 K.LGLVGVNLTLDGVK.S "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 1396.829 1.29 25675 20784 2 1396.828164 699.4218 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 3834.7 - 1.47E+06 - - - -0.5742 - 2.809 0.516 - 661.3 1 2 0 -0.0008 14 0 0 0 3.90E+07 3.01E+07 - - - 5.4438 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20787.20787.2 0.000188 20-Nov K.SLPASLSFLVK.L "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN" 5 1160.6805 1.54 25678 20787 2 1160.682569 581.3475 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 8.47 3835.1 - 879228 - - - 1.7731 - 1.769 0.394 - 238.3 1 2 0 0.0021 11 0 0 0 6.10E+06 3.96E+06 - - - 3.4935 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.20788.20788.2 0.00862 18-Oct R.QALTDFLLAR.K "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1146.6397 1.19 25679 20788 2 1146.639482 574.3271 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.84 3835.2 - 787713 - - - -0.1971 - 1.863 0.18 - 235.2 1 2 0 -0.0002 10 0 0 0 2.76E+06 2.32E+06 - - - 2.1071 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20790.20790.2 0.0154 13/24 K.ALVLANPEVSLWR.K "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 1466.8245 1.82 25681 20790 2 1466.825457 734.4196 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6.05 3835.5 - 638812 - - - 0.619 - 2.382 0.318 - 510.6 1 2 0 0.0009 13 0 0 0 9.16E+06 5.03E+06 - - - 3.6171 1 230117_WJC_METTL3_WT_vs_EV_F03.20792.20792.2 1.08E-08 26-Dec K.NLPIYSEEIVEMYK.G "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1726.8488 1.56 25683 20792 2 1726.847249 864.4317 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3835.8 - 559758 - - - -0.8837 - 2.724 0.521 - 326.9 1 2 0 -0.0015 14 0 0 0 4.31E+06 2.76E+06 - - - 5.4033 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.20793.20793.2 1.45E-05 13/20 R.QLLEEMLTSYR[166.11].L sp|O75688|PPM1B_HUMAN 1 1391.6994 0.41 25684 20793 2 1391.697949 696.857 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3835.9 - 535848 - - - -1.0584 - 2.431 0.403 - 741.7 1 2 0 -0.0015 11 0 0 0 3.00E+07 7.38E+07 - - - 4.4202 1 230117_WJC_METTL3_WT_vs_EV_F03.20795.20795.2 1.83E-05 30-Dec R.IASLPVEVQEVSLLDK.L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1738.9717 2.09 25686 20795 2 1738.972604 870.4931 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.14 3836.2 - 451513 - - - 0.5388 - 2.514 0.502 - 326.6 1 2 0 0.0009 16 0 0 0 1.69E+07 8.11E+06 - - - 5.015 1 230117_WJC_METTL3_WT_vs_EV_F03.20796.20796.2 8.41E-05 17/24 K.LLEQALVIEEQLR[166.11].R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1562.8907 1.55 25687 20796 2 1562.88898 782.4526 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3836.3 - 438044 - - - -1.1184 - 2.936 0.397 - 1381.6 1 2 0 -0.0017 13 0 0 0 2.03E+07 1.31E+07 - - - 4.737 1 230117_WJC_METTL3_WT_vs_EV_F03.20797.20797.2 3.74E-10 17/28 K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 0.74 25688 20797 2 1521.871993 761.945 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3836.4 - 356797 - - - -2.2466 - 3.241 0.624 - 865.7 1 2 0 -0.0034 15 0 0 0 1.08E+07 1.45E+07 - - - 6.5398 0.9752 230117_WJC_METTL3_WT_vs_EV_F03.20800.20800.2 0.425 20-Apr R.LLLQAIQSFEK.K "sp|O14920|IKKB_HUMAN,tr|A0A499FJS7|A0A499FJS7_HUMAN" 2 1288.7391 2.29 25690 20800 2 1288.738563 645.3768 Inhibitor of nuclear factor kappa-B kinase subunit beta OS=Homo sapiens OX=9606 GN=IKBKB PE=1 SV=1 6 3836.7 - 0 - - - -0.4074 - 1.19 0.172 - 19.6 14 2 0 -0.0005 11 0 0 0 6.75E+06 2.95E+06 - - - 0.2698 1 230117_WJC_METTL3_WT_vs_EV_F03.20801.20801.2 6.03E-07 24-Oct K.VLGTAFDPFLGGK[136.11].N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1328.722 8.82 25691 20801 2 1328.725853 665.3683 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3836.7 - 2.46E+06 - - - 2.9088 - 2.166 0.631 - 222 1 2 0 0.0039 13 0 0 0 3.98E+08 4.51E+07 - - - 5.684 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20804.20804.3 0.0256 Aug-56 K.TVAGQDAVIVLLGTR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1511.8671 0.99 25694 20804 3 1511.866266 504.963 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3836.9 - 0 - - - -0.5794 - 1.7 0.395 - 114.1 1 2 0 -0.0009 15 0 0 0 7.25E+06 7.33E+06 - - - 4.3282 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.20807.20807.2 0.0726 20-Jul K.TLPLFYGSIVR[166.11].F "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1274.7262 1.08 25696 20807 2 1274.727374 638.3704 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 8.41 3837.2 - 2.08E+06 - - - 0.8982 - 1.492 0.282 - 196.9 1 2 0 0.0011 11 0 0 0 2.29E+07 2.11E+07 - - - 2.2059 1 230117_WJC_METTL3_WT_vs_EV_F03.20809.20809.2 0.000229 15/24 K.LLEQALVIEEQLR.R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1552.8825 1.54 25697 20809 2 1552.886268 777.4485 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3837.5 - 8.60E+06 - - - 2.4535 - 3.002 0.386 - 907.4 1 2 0 0.0038 13 0 0 0 2.03E+07 1.32E+07 - - - 4.7121 1 230117_WJC_METTL3_WT_vs_EV_F03.20810.20810.2 3.24E-05 13/20 R.QLLEEMLTSYR.L sp|O75688|PPM1B_HUMAN 1 1381.6912 0.41 25698 20810 2 1381.69474 691.8529 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3837.5 - 1.33E+07 - - - 2.5968 - 2.556 0.533 - 804.8 1 2 0 0.0036 11 0 0 0 3.00E+07 7.38E+07 - - - 5.5153 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.20811.20811.3 3.31E-05 14/48 K.LLEQALVIEEQLR.R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1552.8825 1.97 25699 20811 3 1552.881644 518.6348 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3837.6 - 8.54E+06 - - - -0.5242 - 2.557 0.448 - 364.5 1 2 0 -0.0008 13 0 0 0 1.38E+07 7.00E+06 - - - 6.08 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20812.20812.2 0.0369 20-Sep K.LLPAITILGC[160.03]R.V "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 2 1225.7217 2.58 25700 20812 2 1225.722951 613.8681 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 8.25 3837.6 - 7.59E+06 - - - 1.05 - 1.838 0.332 - 276.9 1 2 0 0.0013 11 0 0 0 1.70E+07 6.58E+06 - - - 3.1394 1 230117_WJC_METTL3_WT_vs_EV_F03.20813.20813.2 6.35E-07 16/28 K.TVAGQDAVIVLLGTR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1511.8671 0.75 25701 20813 2 1511.866076 756.9408 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3837.7 - 7.02E+06 - - - -0.7051 - 3.157 0.611 - 694.5 1 2 0 -0.0011 15 0 0 0 1.08E+07 1.45E+07 - - - 6.3799 1 230117_WJC_METTL3_WT_vs_EV_F03.20814.20814.2 0.00012 22-Nov K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 1.35 25702 20814 2 1314.791556 658.4028 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3837.8 - 6.78E+06 - - - 0.3286 - 2.187 0.476 - 413.4 1 2 0 0.0004 12 0 0 0 7.02E+07 5.21E+07 - - - 4.6156 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.20815.20815.3 0.000583 15/48 K.LLEQALVIEEQLR[166.11].R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1562.8907 1.97 25703 20815 3 1562.890912 521.9709 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3837.9 - 5.62E+06 - - - 0.1177 - 2.31 0.356 - 414.6 1 2 0 0.0002 13 0 0 0 1.38E+07 7.00E+06 - - - 4.779 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.20816.20816.3 7.39E-06 14/56 K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 1.01 25704 20816 3 1521.875179 508.2991 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3838 - 4.71E+06 - - - -0.1531 - 2.259 0.434 - 297.2 1 2 0 -0.0002 15 0 0 0 7.23E+06 7.13E+06 - - - 5.505 0.939 230117_WJC_METTL3_WT_vs_EV_F03.20822.20822.2 0.0386 14-Sep K.IAVMELFR.P "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H198|F5H198_HUMAN,tr|A0A7P0TAX4|A0A7P0TAX4_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 14 977.5368 1.97 25710 20822 2 977.536944 489.7757 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 6 3838.6 - 1.87E+06 - - - 0.1238 - 2.043 0.244 - 259.8 1 1 0 0.0001 8 0 0 0 4.22E+06 2.14E+06 - - - 2.9978 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.20828.20828.2 0.00524 14-Aug R.QVLPFLLR[166.11].R "sp|O14981|BTAF1_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 2 994.6203 -1 25716 20828 2 994.618825 498.3174 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 9.75 3839.4 - 545532 - - - -1.49 - 1.603 0.282 - 203.3 1 2 0 -0.0015 8 0 0 0 0.00E+00 0.00E+00 - - - 2.5465 1 230117_WJC_METTL3_WT_vs_EV_F03.20830.20830.2 8.69E-07 15/26 K.LGLVGVNLTLDGVK[136.11].S "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 1404.8432 1.29 25717 20830 2 1404.842414 703.4289 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 3839.6 - 3.24E+06 - - - -0.5353 - 3.089 0.534 - 777.1 1 2 0 -0.0008 14 0 0 0 3.90E+07 3.01E+07 - - - 5.8152 1 230117_WJC_METTL3_WT_vs_EV_F03.20833.20833.2 9.85E-08 14/24 R.LGSTIFVANLDFK.V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1423.7711 2 25720 20833 2 1423.770532 712.8928 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3840 - 1.16E+06 - - - -0.4109 - 3.147 0.524 - 802.6 1 2 0 -0.0006 13 0 0 0 1.64E+07 8.18E+06 - - - 5.8535 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.20836.20836.3 0.000317 Dec-44 R.EGFLDTLVVLHR.A "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 1397.7667 -1 25723 20836 3 1397.766775 466.9295 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.32 3840.4 - 702056 - - - 0.0537 - 2.325 0.454 - 140.1 1 2 0 0.0001 12 0 0 0 0.00E+00 0.00E+00 - - - 5.9403 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.20837.20837.2 2.70E-06 18-Oct K.GYGFVSFFNK.W "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN" 4 1164.5604 1.15 25724 20837 2 1164.561979 583.2875 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 8.59 3840.5 - 673728 - - - 1.3602 - 1.822 0.498 - 308.8 1 2 0 0.0016 10 0 0 0 3.03E+06 2.64E+06 - - - 4.3933 0.999 230117_WJC_METTL3_WT_vs_EV_F03.20838.20838.3 0.00401 Dec-60 R.IASLPVEVQEVSLLDK.L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1738.9717 2.5 25725 20838 3 1738.970998 580.6645 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.14 3840.6 - 551317 - - - -0.3847 - 2.152 0.282 - 143.9 1 2 0 -0.0007 16 0 0 0 1.67E+06 6.67E+05 - - - 3.6503 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20840.20840.2 3.64E-06 30-Sep R.LPC[160.03]IYLVDSGGAYLPR.Q "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJW5|A0A804HJW5_HUMAN,tr|A0A0G2JM88|A0A0G2JM88_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HIH3|A0A804HIH3_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|D6RDF7|D6RDF7_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HJW2|A0A804HJW2_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|D6R9R1|D6R9R1_HUMAN,tr|A0A804HHS4|A0A804HHS4_HUMAN,tr|A0A0S2Z5R4|A0A0S2Z5R4_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 16 1792.9182 -1 25727 20840 2 1792.915933 897.4664 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.83 3840.9 - 467368 - - - -1.26 - 2.248 0.443 - 154.4 1 2 0 -0.0023 16 0 0 0 0.00E+00 0.00E+00 - - - 4.3038 1 230117_WJC_METTL3_WT_vs_EV_F03.20842.20842.2 6.96E-09 14/26 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.96 25729 20842 2 1669.892658 835.9552 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3841.1 - 381178 - - - -1.9594 - 2.604 0.57 - 573.1 1 2 0 -0.0033 14 0 0 0 7.06E+07 7.39E+07 - - - 5.6517 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20845.20845.2 0.0186 14-Aug R.QVLPFLLR.R "sp|O14981|BTAF1_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 2 984.612 1.48 25732 20845 2 984.611863 493.3133 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 9.75 3841.5 - 344665 - - - -0.1767 - 1.633 0.356 - 251.4 1 2 0 -0.0002 8 0 0 0 1.40E+06 9.50E+05 - - - 3.1494 0.9903 230117_WJC_METTL3_WT_vs_EV_F03.20849.20849.2 0.137 24-Jul K.ALVLANPEVSLWR[166.11].K "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 1476.8328 1.9 25736 20849 2 1476.830852 739.4237 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6.05 3842 - 320916 - - - -1.3319 - 1.305 0.227 - 131.9 1 2 0 -0.002 13 0 0 0 9.56E+06 5.03E+06 - - - 1.4002 0.9919 230117_WJC_METTL3_WT_vs_EV_F03.20852.20852.3 0.0289 Aug-44 R.EGFLDTLVVLHR[166.11].A "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 1407.775 1.31 25738 20852 3 1407.778269 470.2656 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.32 3842.5 - 58555.5 - - - 2.3434 - 1.335 0.217 - 55.5 1 2 0 0.0033 12 0 0 0 1.49E+06 1.14E+06 - - - 1.7593 1 230117_WJC_METTL3_WT_vs_EV_F03.20855.20855.2 4.13E-09 15/26 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.96 25741 20855 2 1661.885016 831.9481 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3842.7 - 837122 - - - 1.9773 - 2.76 0.598 - 601.4 1 2 0 0.0033 14 0 0 0 7.06E+07 7.39E+07 - - - 6.0045 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.20858.20858.3 9.74E-05 15/44 K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 2.14 25744 20858 3 1314.79531 439.271 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3843.1 - 69054.8 - - - 3.1838 - 2.561 0.459 - 406.5 1 2 0 0.0042 12 0 0 0 1.19E+06 5.56E+05 - - - 6.2629 0.9964 230117_WJC_METTL3_WT_vs_EV_F03.20860.20860.2 0.0231 24-Jul R.QMDIIVSEVSMIR[166.11].D "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1529.7821 -1 25746 20860 2 1529.779519 765.8983 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.37 3843.3 - 0 - - - -1.6911 - 1.442 0.348 - 124.4 1 2 0 -0.0026 13 0 0 0 0.00E+00 0.00E+00 - - - 2.5499 0.9675 230117_WJC_METTL3_WT_vs_EV_F03.20864.20864.3 0.000248 Aug-36 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 -1 25750 20864 3 1343.611684 448.8778 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3843.9 - 92417.9 - - - 0.1652 - 1.685 0.513 - 146.4 1 1 0 0.0002 10 0 0 0 0.00E+00 0.00E+00 - - - 5.7832 1 230117_WJC_METTL3_WT_vs_EV_F03.20868.20868.2 4.86E-06 22-Aug K.LVTLPVSFAQLK[136.11].N sp|Q96AG4|LRC59_HUMAN 1 1322.8053 1.35 25751 20868 2 1322.806004 662.4099 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3844.2 - 635118 - - - 0.5141 - 2.081 0.573 - 215.2 1 2 0 0.0007 12 0 0 0 7.02E+07 5.21E+07 - - - 5.2012 0.9974 230117_WJC_METTL3_WT_vs_EV_F03.20872.20872.2 0.0138 20-Jun K.ELGIWEPLAVK.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1253.702 10.04 25753 20872 2 1253.705306 627.8583 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3844.6 - 565399 - - - 2.6577 - 1.23 0.304 - 115.9 1 2 0 0.0033 11 0 0 0 1.08E+09 1.08E+08 - - - 1.8453 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.20874.20874.3 0.00104 Sep-52 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 1.05 25755 20874 3 1661.88551 554.9679 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3844.8 - 622346 - - - 2.2745 - 1.945 0.417 - 97.4 1 2 0 0.0038 14 0 0 0 1.19E+07 1.13E+07 - - - 4.956 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20877.20877.3 0.00131 13/52 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 1.05 25756 20877 3 1669.895189 557.6393 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3845.2 - 4.40E+06 - - - -0.4437 - 1.869 0.351 - 216.2 1 2 0 -0.0007 14 0 0 0 1.19E+07 1.13E+07 - - - 4.1151 1 230117_WJC_METTL3_WT_vs_EV_F03.20878.20878.2 0.00037 20-Dec K.VSVFFGGLSIK.K "sp|O00148|DX39A_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|A0A0D9SEM9|A0A0D9SEM9_HUMAN" 3 1152.6543 3.92 25757 20878 2 1152.653649 577.3344 ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2 8.72 3845.2 - 3.88E+06 - - - -0.5613 - 2.042 0.503 - 462.3 1 2 0 -0.0006 11 0 0 0 9.23E+06 2.35E+06 - - - 4.6873 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.20880.20880.2 0.01 16-Sep K.ITFLLQAIR.N "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1073.6597 1.3 25759 20880 2 1073.66056 537.8371 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 3845.3 - 4.34E+06 - - - 0.7861 - 2.046 0.393 - 255.6 1 2 0 0.0008 9 0 0 0 1.34E+07 1.03E+07 - - - 4.0145 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20881.20881.2 0.00721 16-Oct K.ITFLLQAIR[166.11].N "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1083.668 1.3 25760 20881 2 1083.668727 542.8413 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 3845.4 - 4.24E+06 - - - 0.6838 - 1.831 0.384 - 304.2 1 2 0 0.0007 9 0 0 0 1.34E+07 1.03E+07 - - - 3.6269 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20882.20882.2 0.0184 16-Nov K.TLDDLFPLR[166.11].S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1098.5949 1.46 25761 20882 2 1098.595845 550.3047 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.21 3845.4 - 3.54E+06 - - - 0.8784 - 1.916 0.363 - 383.9 1 2 0 0.001 9 0 0 0 1.61E+07 1.10E+07 - - - 3.603 1 230117_WJC_METTL3_WT_vs_EV_F03.20883.20883.2 3.00E-05 20-Nov K.VAVFFGGLSIK.K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1136.6594 0.77 25762 20883 2 1136.660847 569.337 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3845.5 - 2.77E+06 - - - 1.2897 - 2.387 0.499 - 473.2 1 2 0 0.0015 11 0 0 0 1.31E+07 1.70E+07 - - - 5.0798 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.20884.20884.2 0.0649 18-Oct R.MALLATVLGR.F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1043.6161 2.27 25763 20884 2 1043.617667 522.8153 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.5 3845.6 - 1.73E+06 - - - 1.467 - 2.204 0.364 - 439.3 1 2 0 0.0015 10 0 0 0 1.47E+07 6.46E+06 - - - 3.9349 1 230117_WJC_METTL3_WT_vs_EV_F03.20885.20885.2 2.92E-06 24-Nov R.VLLFTDDVALVSK.A "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1418.8021 1.31 25764 20885 2 1418.804648 710.4083 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.21 3845.7 - 1.33E+06 - - - 1.8086 - 2.564 0.595 - 290.1 1 2 0 0.0026 13 0 0 0 4.75E+06 3.62E+06 - - - 5.8514 1 230117_WJC_METTL3_WT_vs_EV_F03.20886.20886.2 3.53E-08 20-Nov K.VLYVYDMLAGK[136.11].L "sp|Q9Y5J1|UTP18_HUMAN,tr|J3KSR7|J3KSR7_HUMAN" 2 1278.6773 0.93 25765 20886 2 1278.680566 640.3459 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 5.8 3845.9 - 1.24E+06 - - - 2.5182 - 2.493 0.588 - 365.2 1 2 0 0.0032 11 0 0 0 3.65E+06 3.93E+06 - - - 5.8542 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.20891.20891.2 0.000385 24-Oct K.IAVPLIQGYTVLR.L sp|Q8IW92|GLBL2_HUMAN 1 1441.8657 0.97 25770 20891 2 1441.870155 721.9401 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3846.5 - 512844 - - - 3.0995 - 1.944 0.39 - 295.9 1 2 0 0.0045 13 0 0 0 5.42E+06 5.57E+06 - - - 3.6262 0.9941 230117_WJC_METTL3_WT_vs_EV_F03.20892.20892.2 0.00112 24-Nov K.IAVPLIQGYTVLR[166.11].L sp|Q8IW92|GLBL2_HUMAN 1 1451.874 0.97 25771 20892 2 1451.882829 726.9443 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3846.6 - 481479 - - - 6.1114 - 1.844 0.401 - 417.9 1 2 0 0.0089 13 0 0 0 5.42E+06 5.57E+06 - - - 3.5706 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20893.20893.2 0.00235 20-Aug R.LLIIASIGQLK.T "sp|Q15813|TBCE_HUMAN,tr|A0A2R8YFL4|A0A2R8YFL4_HUMAN,tr|A0A2R8Y5Q8|A0A2R8Y5Q8_HUMAN,tr|A0A2R8Y7E7|A0A2R8Y7E7_HUMAN,tr|A0A2R8Y6Q1|A0A2R8Y6Q1_HUMAN,tr|A0A2R8YHI9|A0A2R8YHI9_HUMAN,tr|A0A2U3TZJ6|A0A2U3TZJ6_HUMAN" 7 1167.7591 -1 25772 20893 2 1167.760522 584.8868 Tubulin-specific chaperone E OS=Homo sapiens OX=9606 GN=TBCE PE=1 SV=1 8.75 3846.7 - 421435 - - - 1.222 - 1.701 0.34 - 134 1 2 0 0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 2.9889 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.20894.20894.2 0.152 14-Jul K.VLFPLLTK[136.11].L "sp|Q92538|GBF1_HUMAN,tr|A0A7I2YQM2|A0A7I2YQM2_HUMAN,tr|A0A669KBG8|A0A669KBG8_HUMAN,tr|A0A7I2V329|A0A7I2V329_HUMAN,tr|A0A7I2V2L5|A0A7I2V2L5_HUMAN,tr|A0A7I2V514|A0A7I2V514_HUMAN,tr|A0A7I2YQ65|A0A7I2YQ65_HUMAN,tr|A0A669KB10|A0A669KB10_HUMAN,tr|A0A7I2V452|A0A7I2V452_HUMAN,tr|A0A7I2V622|A0A7I2V622_HUMAN,tr|A0A7I2V4F9|A0A7I2V4F9_HUMAN,tr|A0A7I2YQN3|A0A7I2YQN3_HUMAN,tr|A0A7I2V529|A0A7I2V529_HUMAN,tr|A0A7P0RGV0|A0A7P0RGV0_HUMAN" 14 937.6092 -1 25773 20894 2 937.610243 469.8119 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=GBF1 PE=1 SV=2 8.72 3846.9 - 345494 - - - 1.1231 - 1.244 0.239 - 96.4 1 2 0 0.0011 8 0 0 0 0.00E+00 0.00E+00 - - - 1.4644 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.20895.20895.2 0.0528 20-Sep R.LLIIASIGQLK[136.11].T "sp|Q15813|TBCE_HUMAN,tr|A0A2R8YFL4|A0A2R8YFL4_HUMAN,tr|A0A2R8Y5Q8|A0A2R8Y5Q8_HUMAN,tr|A0A2R8Y7E7|A0A2R8Y7E7_HUMAN,tr|A0A2R8Y6Q1|A0A2R8Y6Q1_HUMAN,tr|A0A2R8YHI9|A0A2R8YHI9_HUMAN,tr|A0A2U3TZJ6|A0A2U3TZJ6_HUMAN" 7 1175.7733 -1 25774 20895 2 1175.774815 588.8939 Tubulin-specific chaperone E OS=Homo sapiens OX=9606 GN=TBCE PE=1 SV=1 8.75 3847 - 330423 - - - 1.2928 - 1.287 0.233 - 128 1 2 0 0.0015 11 0 0 0 0.00E+00 0.00E+00 - - - 1.444 0.9819 230117_WJC_METTL3_WT_vs_EV_F03.20896.20896.3 0.117 Jun-40 K.VPPPWLIAMQR.Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1306.722 1.29 25775 20896 3 1306.72756 436.5813 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3847.1 - 300069 - - - 4.2565 - 1.557 0.219 - 57.6 3 2 0 0.0056 11 0 0 0 1.32E+06 1.03E+06 - - - 2.0171 1 230117_WJC_METTL3_WT_vs_EV_F03.20899.20899.2 3.90E-06 20-Sep K.VLYVYDMLAGK.L "sp|Q9Y5J1|UTP18_HUMAN,tr|J3KSR7|J3KSR7_HUMAN" 2 1270.6631 0.94 25777 20899 2 1270.665602 636.3388 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 5.8 3847.6 - 703435 - - - 1.9328 - 2.048 0.57 - 244.9 1 2 0 0.0025 11 0 0 0 3.65E+06 3.86E+06 - - - 5.1895 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.20900.20900.2 0.00571 16-Nov K.TLDDLFPLR.S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1088.5866 1.44 25778 20900 2 1088.587529 545.3006 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.21 3847.8 - 2.15E+06 - - - 0.8442 - 2.108 0.437 - 380.9 1 2 0 0.0009 9 0 0 0 1.59E+07 1.10E+07 - - - 4.4259 1 230117_WJC_METTL3_WT_vs_EV_F03.20901.20901.2 0.0307 18-Dec R.MALLATVLGR[166.11].F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1053.6244 2.27 25779 20901 2 1053.626853 527.8195 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.5 3847.9 - 1.25E+06 - - - 2.3225 - 2.429 0.437 - 729.7 1 2 0 0.0024 10 0 0 0 1.47E+07 6.46E+06 - - - 4.7451 1 230117_WJC_METTL3_WT_vs_EV_F03.20902.20902.2 5.76E-07 24-Dec R.VLLFTDDVALVSK[136.11].A "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1426.8163 1.31 25780 20902 2 1426.819913 714.4154 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.21 3848 - 634875 - - - 2.5448 - 2.435 0.522 - 313.1 1 2 0 0.0036 13 0 0 0 4.75E+06 3.62E+06 - - - 5.1794 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.20903.20903.2 0.182 14-Jul R.DFLLDIAR[166.11].Q "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 971.5316 1.38 25781 20903 2 971.533409 486.7731 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 3848.2 - 556360 - - - 1.9114 - 1.273 0.22 - 197.9 1 2 0 0.0019 8 0 0 0 2.36E+07 1.71E+07 - - - 1.3933 1 230117_WJC_METTL3_WT_vs_EV_F03.20907.20907.2 2.28E-05 14/24 K.AAILPTSIFLTNK[136.11].K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1395.8217 0.48 25785 20907 2 1395.82103 698.9181 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3848.7 - 279529 - - - -0.4814 - 2.585 0.492 - 518 1 2 0 -0.0007 13 0 0 0 3.90E+07 8.13E+07 - - - 5.1122 0.997 230117_WJC_METTL3_WT_vs_EV_F03.20908.20908.2 2.91E-07 26-Nov R.WEGPLSVSVFAATK[136.11].E sp|O43505|B4GA1_HUMAN 1 1498.7911 1.03 25786 20908 2 1498.787301 750.4028 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 6 3848.8 - 247108 - - - -2.5547 - 2.25 0.331 - 409.7 1 2 0 -0.0038 14 0 0 0 2.20E+06 2.13E+06 - - - 3.5196 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20912.20912.2 0.000819 18-Aug R.DFILPISDVR[166.11].A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|Q4VXM0|Q4VXM0_HUMAN,tr|Q4VXM1|Q4VXM1_HUMAN" 5 1183.6476 2.7 25790 20912 2 1183.649627 592.8311 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.21 3849.3 - 191960 - - - 1.6753 - 1.915 0.402 - 250.2 1 2 0 0.002 10 0 0 0 2.34E+07 8.66E+06 - - - 3.8231 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.20919.20919.2 0.000103 20-Sep K.VAVFFGGLSIK[136.11].K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1144.6736 0.76 25796 20919 2 1144.673542 573.3441 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3850.2 - 231631 - - - -0.0341 - 1.916 0.439 - 172.3 1 2 0 0 11 0 0 0 6.18E+06 8.11E+06 - - - 4.0425 1 230117_WJC_METTL3_WT_vs_EV_F03.20929.20929.2 1.18E-05 13/24 K.AAILPTSIFLTNK.K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1387.8075 0.48 25804 20929 2 1387.809197 694.911 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3851.4 - 5.83E+06 - - - 1.2214 - 2.42 0.527 - 473.6 1 2 0 0.0017 13 0 0 0 3.90E+07 8.13E+07 - - - 5.2011 0.9892 230117_WJC_METTL3_WT_vs_EV_F03.20932.20932.2 2.1 16-Aug R.DLLFQALGR.T sp|Q9NSD9|SYFB_HUMAN 1 1031.5764 4.04 25807 20932 2 1031.579326 516.7955 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 5.84 3851.6 - 4.08E+06 - - - 2.8558 - 1.441 0.093 - 182.6 1 2 0 0.0029 9 0 0 0 2.31E+07 5.72E+06 - - - 0.7839 1 230117_WJC_METTL3_WT_vs_EV_F03.20935.20935.2 3.86E-05 20-Dec R.FDEISFVNFAR[166.11].G sp|Q08945|SSRP1_HUMAN 1 1353.6593 0.82 25810 20935 2 1353.658967 677.8369 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3851.7 - 3.12E+06 - - - -0.2246 - 2.318 0.487 - 619.1 1 2 0 -0.0003 11 0 0 0 1.16E+07 1.41E+07 - - - 4.9122 0.993 230117_WJC_METTL3_WT_vs_EV_F03.20937.20937.2 0.0786 12-May K.YFLWVVK.F sp|P62993|GRB2_HUMAN 1 953.5375 13.15 25812 20937 2 953.537458 477.776 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 8.59 3851.9 - 2.74E+06 - - - -0.0178 - 1.175 0.199 - 85 1 2 0 0 7 0 0 0 7.80E+06 5.94E+05 - - - 1.0218 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.20938.20938.2 0.00128 20-Nov R.TSLGNVVLLLK.S "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1155.7227 1.81 25813 20938 2 1155.723326 578.8686 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 8.41 3851.9 - 2.56E+06 - - - 0.533 - 2.317 0.409 - 373 1 2 0 0.0006 11 0 0 0 1.16E+07 6.42E+06 - - - 4.3348 1 230117_WJC_METTL3_WT_vs_EV_F03.20940.20940.2 9.78E-10 13/22 K.ITAEEMYDIFGK.Y sp|Q9Y3B4|SF3B6_HUMAN 1 1415.6643 2.87 25815 20940 2 1415.662596 708.8394 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.14 3852.2 - 1.24E+06 - - - -1.1811 - 2.751 0.683 - 723.2 1 2 0 -0.0017 12 0 0 0 5.76E+06 2.00E+06 - - - 6.7478 0.998 230117_WJC_METTL3_WT_vs_EV_F03.20942.20942.2 0.248 20-Nov K.VPPPWLIAMQR[166.11].Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1316.7303 0.92 25817 20942 2 1316.732404 659.3724 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3852.4 - 989668 - - - 1.6222 - 1.848 0.142 - 480.7 1 2 0 0.0021 11 0 0 0 4.23E+06 4.62E+06 - - - 1.7504 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20945.20945.2 0.00107 24-Oct K.LIHIPINNIIVGG.- sp|P60059|SC61G_HUMAN 1 1371.8238 - 25820 20945 2 1371.826567 686.9192 Protein transport protein Sec61 subunit gamma OS=Homo sapiens OX=9606 GN=SEC61G PE=1 SV=1 6.74 3852.8 - 664120 - - - 2.0017 - 2.063 0.392 - 201.5 1 2 0 0.0027 13 0 0 0 - - - - - 3.794 0.9949 230117_WJC_METTL3_WT_vs_EV_F03.20951.20951.2 0.000122 20-Dec R.FDEISFVNFAR.G sp|Q08945|SSRP1_HUMAN 1 1343.651 0.82 25825 20951 2 1343.659312 672.8328 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3853.4 - 2.15E+06 - - - 6.1854 - 2.013 0.406 - 383.2 1 2 0 0.0083 11 0 0 0 1.16E+07 1.41E+07 - - - 3.9298 1 230117_WJC_METTL3_WT_vs_EV_F03.20955.20955.2 2.84E-06 20-Oct K.LWC[160.03]SLADYYIR.S sp|Q9HCS7|SYF1_HUMAN 1 1458.6966 1.22 25829 20955 2 1458.697256 730.3556 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 5.83 3853.8 - 875413 - - - 0.4689 - 2.278 0.477 - 469.5 1 2 0 0.0007 11 0 0 0 2.46E+06 2.02E+06 - - - 4.7911 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20956.20956.2 0.00061 20-Nov K.LWC[160.03]SLADYYIR[166.11].S sp|Q9HCS7|SYF1_HUMAN 1 1468.7048 1.29 25830 20956 2 1468.703366 735.3597 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 5.83 3853.9 - 716211 - - - -1.005 - 2.12 0.381 - 386.3 1 2 0 -0.0015 11 0 0 0 2.60E+06 2.02E+06 - - - 3.8874 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20958.20958.2 0.01 16-Aug R.DIVQFVPFR[166.11].E "sp|Q96FN4|CPNE2_HUMAN,sp|O75131|CPNE3_HUMAN,sp|O95741|CPNE6_HUMAN,sp|Q86YQ8|CPNE8_HUMAN,sp|Q8IYJ1|CPNE9_HUMAN,sp|Q9UBL6|CPNE7_HUMAN,sp|Q9HCH3|CPNE5_HUMAN,sp|Q96A23|CPNE4_HUMAN,tr|E7ENV7|E7ENV7_HUMAN" 9 1129.616 2.35 25832 20958 2 1129.615968 565.8153 Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3 5.84 3854.1 - 596430 - - - 0.0159 - 1.835 0.383 - 305.1 1 2 0 0 9 0 0 0 1.12E+07 4.79E+06 - - - 3.626 0.9902 230117_WJC_METTL3_WT_vs_EV_F03.20959.20959.2 0.00315 18-Sep R.TMYLLGYIPK.D "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1197.6468 0.93 25833 20959 2 1197.653516 599.8307 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 8.17 3854.2 - 588984 - - - 5.6344 - 1.455 0.324 - 256.1 1 2 0 0.0067 10 0 0 0 3.96E+06 4.25E+06 - - - 2.4787 1 230117_WJC_METTL3_WT_vs_EV_F03.20961.20961.2 0.00415 20-Dec R.ILEFIAVSQLR.G "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN,tr|K7ER27|K7ER27_HUMAN" 4 1287.7551 1.03 25835 20961 2 1287.75688 644.8848 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 6 3854.5 - 527449 - - - 1.4032 - 2.355 0.446 - 658.8 1 2 0 0.0018 11 0 0 0 2.58E+06 2.51E+06 - - - 4.6517 1 230117_WJC_METTL3_WT_vs_EV_F03.20966.20966.2 6.17E-07 26-Sep K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 20.9 25838 20966 2 1613.805317 807.9078 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3855.1 - 119351 - - - 2.6156 - 1.8 0.576 - 164.4 1 2 0 0.0042 14 0 0 0 4.67E+07 2.24E+06 - - - 4.769 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.20967.20967.2 0.0343 14-Jul R.TLFGFLGK.L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 881.5011 1.55 25839 20967 2 881.503622 441.7578 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3855.2 - 53296.2 - - - 2.8724 - 1.22 0.426 - 146.1 1 2 0 0.0025 8 0 0 0 2.81E+07 1.82E+07 - - - 2.7864 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.20968.20968.2 0.00807 14-Jul R.TLFGFLGK[136.11].L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 889.5153 1.54 25840 20968 2 889.515857 445.7649 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3855.2 - 269850 - - - 0.6374 - 1.281 0.379 - 148.4 1 2 0 0.0006 8 0 0 0 2.81E+07 1.82E+07 - - - 2.587 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.20969.20969.2 0.0275 14-Aug R.DFLLDIAR.Q "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 961.5233 1.38 25841 20969 2 961.523146 481.7689 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 3855.3 - 0 - - - -0.1414 - 1.641 0.279 - 315.5 1 2 0 -0.0001 8 0 0 0 2.35E+07 1.70E+07 - - - 2.5955 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.20975.20975.2 0.221 14-Sep K.VALLDVFR.E "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 931.5491 2.6 25845 20975 2 931.548911 466.7818 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.81 3856.1 - 385004 - - - -0.205 - 1.947 0.292 - 429 1 2 0 -0.0002 8 0 0 0 5.56E+07 2.13E+07 - - - 3.2072 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.20977.20977.2 0.0127 14-Jul R.VFLWGSFR[166.11].D "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1020.5421 1.05 25847 20977 2 1020.543121 511.2783 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 9.72 3856.2 - 339217 - - - 1.0426 - 1.398 0.283 - 227.9 1 2 0 0.0011 8 0 0 0 7.90E+06 7.49E+06 - - - 2.1414 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.20979.20979.2 0.564 20-Oct K.LEDVLPLAFTR[166.11].L "sp|Q5SSJ5|HP1B3_HUMAN,tr|B0QZK4|B0QZK4_HUMAN,tr|Q5SWC8|Q5SWC8_HUMAN" 3 1282.7161 0.77 25849 20979 2 1282.720465 642.3653 Heterochromatin protein 1-binding protein 3 OS=Homo sapiens OX=9606 GN=HP1BP3 PE=1 SV=1 4.37 3856.4 - 243549 - - - 3.4357 - 2.03 0.256 - 324.4 1 2 0 0.0044 11 0 0 0 6.90E+06 9.01E+06 - - - 2.8458 1 230117_WJC_METTL3_WT_vs_EV_F03.20981.20981.3 3.69E-06 Nov-36 K.YRPLFDYFLK.C "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 1360.718 1.03 25851 20981 3 1360.718809 454.5799 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.5 3856.6 - 0 - - - 0.6247 - 2.074 0.527 - 172.7 1 2 0 0.0008 10 0 0 0 2.00E+06 1.94E+06 - - - 6.5457 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.20982.20982.3 3.28E-05 Nov-52 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 4.69 25852 20982 3 1535.791111 512.9375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3856.7 - 76795.9 - - - 0.377 - 1.843 0.445 - 145 1 2 0 0.0006 14 0 0 0 2.31E+07 4.92E+06 - - - 5.1259 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.20984.20984.2 7.44E-05 24-Aug R.VIYAMAEDGLLFK[136.11].F "sp|P30825|SL7A1_HUMAN,sp|P52569|CTR2_HUMAN,tr|A0A1W2PR06|A0A1W2PR06_HUMAN" 3 1476.7778 3.85 25854 20984 2 1476.777159 739.3962 High affinity cationic amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A1 PE=1 SV=1 4.37 3856.9 - 0 - - - -0.4259 - 1.759 0.453 - 128.2 1 2 0 -0.0006 13 0 0 0 6.22E+06 1.61E+06 - - - 3.8361 1 230117_WJC_METTL3_WT_vs_EV_F03.20986.20986.2 4.42E-07 30-Oct R.VIFLEDDDVAAVVDGR[166.11].L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1741.8762 -1 25856 20986 2 1741.875892 871.9454 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 3.71 3857.2 - 0 - - - -0.1768 - 2.16 0.558 - 220.1 1 2 0 -0.0003 16 0 0 0 0.00E+00 0.00E+00 - - - 5.0556 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.20987.20987.3 1.69E-05 Dec-40 K.FMEAFFSHVLR.G "sp|Q15345|LRC41_HUMAN,tr|A0A087X0S7|A0A087X0S7_HUMAN,tr|A0A087WTU1|A0A087WTU1_HUMAN,tr|A0A0B4J2G4|A0A0B4J2G4_HUMAN" 4 1382.6805 -1 25857 20987 3 1382.680613 461.9008 Leucine-rich repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=LRRC41 PE=1 SV=3 6.75 3857.3 - 153619 - - - 0.0622 - 1.758 0.465 - 127.3 1 2 0 0.0001 11 0 0 0 0.00E+00 0.00E+00 - - - 5.327 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.20989.20989.3 0.000344 Oct-44 K.TLGVDLVALATR.V "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1227.7187 -1 25859 20989 3 1227.718166 410.2468 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.5 3857.6 - 0 - - - -0.4244 - 1.886 0.252 - 146.4 1 2 0 -0.0005 12 0 0 0 0.00E+00 0.00E+00 - - - 3.108 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.20995.20995.2 0.000415 14-Sep R.VFLWGSFR.D "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1010.5338 1.05 25863 20995 2 1010.535954 506.2742 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 9.72 3858.2 - 2.22E+06 - - - 2.1444 - 1.78 0.417 - 406.1 1 2 0 0.0022 8 0 0 0 7.90E+06 7.49E+06 - - - 3.8593 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.20997.20997.2 0.329 14-Aug K.VALLDVFR[166.11].E "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 941.5574 2.6 25865 20997 2 941.558553 471.786 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.81 3858.4 - 5.74E+06 - - - 1.2543 - 1.846 0.16 - 315.4 1 2 0 0.0012 8 0 0 0 5.54E+07 2.13E+07 - - - 2.0712 1 230117_WJC_METTL3_WT_vs_EV_F03.20998.20998.2 0.00641 15/22 K.TLGVDLVALATR[166.11].V "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1237.727 2.05 25866 20998 2 1237.729757 619.8708 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.5 3858.5 - 3.92E+06 - - - 2.2622 - 2.447 0.446 - 685.4 1 2 0 0.0028 12 0 0 0 2.91E+07 1.42E+07 - - - 4.6888 1 230117_WJC_METTL3_WT_vs_EV_F03.21000.21000.3 1.07E-09 15/52 K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 14.13 25868 21000 3 1613.80455 538.941 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3858.6 - 2.79E+06 - - - 2.1403 - 2.685 0.498 - 319.6 1 2 0 0.0035 14 0 0 0 4.30E+08 3.04E+07 - - - 6.716 1 230117_WJC_METTL3_WT_vs_EV_F03.21001.21001.2 1.14E-05 15/26 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 4.44 25869 21001 2 1535.793065 768.9025 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3858.8 - 2.46E+06 - - - 1.6493 - 2.623 0.501 - 663.4 1 2 0 0.0025 14 0 0 0 8.01E+07 1.81E+07 - - - 5.1605 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21003.21003.2 0.000246 20-Dec K.LEDVLPLAFTR.L "sp|Q5SSJ5|HP1B3_HUMAN,tr|B0QZK4|B0QZK4_HUMAN,tr|Q5SWC8|Q5SWC8_HUMAN" 3 1272.7078 0.77 25871 21003 2 1272.709948 637.3612 Heterochromatin protein 1-binding protein 3 OS=Homo sapiens OX=9606 GN=HP1BP3 PE=1 SV=1 4.37 3859 - 1.81E+06 - - - 1.6972 - 2.3 0.369 - 513.4 1 2 0 0.0022 11 0 0 0 6.90E+06 9.01E+06 - - - 4.019 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21004.21004.2 1.15E-06 14/22 R.LGLQNDLFSLAR.A "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1345.7354 -1 25872 21004 2 1345.738495 673.875 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.84 3859.2 - 1.29E+06 - - - 2.2999 - 2.089 0.458 - 519.4 1 2 0 0.0031 12 0 0 0 0.00E+00 0.00E+00 - - - 4.3612 1 230117_WJC_METTL3_WT_vs_EV_F03.21005.21005.2 0.000254 20-Dec R.PLEVFMC[160.03]SVLK[136.11].R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1329.6916 3.03 25873 21005 2 1329.692141 665.8531 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.38 3859.3 - 902488 - - - 0.3948 - 2.323 0.506 - 455.2 1 1 0 0.0005 11 0 0 0 1.97E+07 6.50E+06 - - - 5.0583 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21006.21006.2 1.50E-05 20-Sep K.DFPLSGYVELR.Y sp|O75489|NDUS3_HUMAN 1 1294.6558 1.81 25874 21006 2 1294.65713 648.3352 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 4.37 3859.4 - 851687 - - - 1.0644 - 1.867 0.415 - 281.4 1 2 0 0.0014 11 0 0 0 5.41E+06 2.98E+06 - - - 3.7947 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21007.21007.2 0.000326 13/22 R.LGLQNDLFSLAR[166.11].A "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1355.7437 -1 25875 21007 2 1355.744268 678.8791 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.84 3859.5 - 835556 - - - 0.4411 - 2.372 0.373 - 518.5 1 2 0 0.0006 12 0 0 0 0.00E+00 0.00E+00 - - - 4.0684 0.9948 230117_WJC_METTL3_WT_vs_EV_F03.21009.21009.2 0.529 16-Sep R.DLLFQALGR[166.11].T sp|Q9NSD9|SYFB_HUMAN 1 1041.5847 4.11 25877 21009 2 1041.588308 521.7996 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 5.84 3859.8 - 793156 - - - 3.512 - 1.51 0.197 - 168.6 1 2 0 0.0037 9 0 0 0 2.31E+07 5.63E+06 - - - 1.6871 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21013.21013.2 4.92E-05 16-Aug K.YPENFFLLR.G "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|C9J9S3|C9J9S3_HUMAN,tr|E7ETD8|E7ETD8_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 12 1197.6182 0.96 25881 21013 2 1197.618456 599.8164 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 6 3860.3 - 611463 - - - 0.1762 - 1.863 0.46 - 241 1 2 0 0.0002 9 0 0 0 3.02E+06 3.16E+06 - - - 4.2385 1 230117_WJC_METTL3_WT_vs_EV_F03.21020.21020.2 7.20E-06 18-Dec R.WYEWLDPSIK.K sp|Q99459|CDC5L_HUMAN 1 1335.6499 1.39 25887 21020 2 1335.65072 668.8322 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3861.1 - 2.01E+06 - - - 0.5847 - 2.058 0.504 - 499.8 1 2 0 0.0008 10 0 0 0 9.48E+06 6.85E+06 - - - 4.7779 1 230117_WJC_METTL3_WT_vs_EV_F03.21021.21021.2 2.52E-09 17/28 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 3.47 25888 21021 2 1700.899394 851.4565 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3861.2 - 1.89E+06 - - - 0.5244 - 3.372 0.627 - 789.5 1 2 0 0.0009 15 0 0 0 6.37E+08 1.84E+08 - - - 6.6601 0.994 230117_WJC_METTL3_WT_vs_EV_F03.21024.21024.2 1.02 22-Aug R.TNVINEILSTER[166.11].D "sp|Q9NR80|ARHG4_HUMAN,tr|A0A0C4DFY6|A0A0C4DFY6_HUMAN,tr|A0A087X0P1|A0A087X0P1_HUMAN,tr|E9PEM0|E9PEM0_HUMAN,tr|E7EV07|E7EV07_HUMAN" 5 1397.739 0.7 25891 21024 2 1397.740085 699.8768 Rho guanine nucleotide exchange factor 4 OS=Homo sapiens OX=9606 GN=ARHGEF4 PE=1 SV=3 4.53 3861.5 - 1.73E+06 - - - 0.792 - 1.494 0.125 - 143.6 2 2 0 0.0011 12 0 0 0 3.35E+06 4.80E+06 - - - 0.8857 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.21025.21025.2 0.015 14-Aug R.IPFTFWAR.Y sp|Q9Y5V3|MAGD1_HUMAN 1 1036.5494 1.29 25892 21025 2 1036.551453 519.282 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 9.75 3861.7 - 1.62E+06 - - - 1.9449 - 1.495 0.358 - 241.6 1 2 0 0.002 8 0 0 0 1.01E+07 7.84E+06 - - - 2.8973 1 230117_WJC_METTL3_WT_vs_EV_F03.21026.21026.2 1.16E-05 26-Dec K.TFAPEEISAMVLTK[136.11].M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1543.8047 -1 25893 21026 2 1543.806485 772.9096 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3861.8 - 1.61E+06 - - - 1.1355 - 2.154 0.529 - 394.5 1 2 0 0.0018 14 0 0 0 0.00E+00 0.00E+00 - - - 4.8732 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.21029.21029.2 0.00982 14-Jul R.FFFNLGVK.A sp|Q01804|OTUD4_HUMAN 1 970.5276 -1 25896 21029 2 970.528249 486.2711 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 8.75 3862.1 - 1.01E+06 - - - 0.6285 - 1.356 0.372 - 90.8 1 2 0 0.0006 8 0 0 0 0.00E+00 0.00E+00 - - - 2.7069 1 230117_WJC_METTL3_WT_vs_EV_F03.21030.21030.2 2.93E-08 13/26 K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 -1 25897 21030 2 1621.821973 811.9149 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3862.3 - 981814 - - - 4.117 - 2.46 0.578 - 431.5 1 2 0 0.0067 14 0 0 0 0.00E+00 0.00E+00 - - - 5.5669 1 230117_WJC_METTL3_WT_vs_EV_F03.21031.21031.3 6.72E-08 18/56 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 6.08 25898 21031 3 1700.901133 567.9734 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3862.4 - 800218 - - - 1.5468 - 3.394 0.58 - 522.2 1 2 0 0.0026 15 0 0 0 1.85E+08 3.04E+07 - - - 8.1944 1 230117_WJC_METTL3_WT_vs_EV_F03.21032.21032.2 1.76E-06 13/22 R.LEGLTDEINFLR.Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1418.7405 1.89 25899 21032 2 1418.741899 710.3775 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3862.5 - 779554 - - - 0.9544 - 2.774 0.55 - 672.3 1 2 0 0.0014 12 0 0 0 2.33E+07 1.24E+07 - - - 5.7874 1 230117_WJC_METTL3_WT_vs_EV_F03.21033.21033.2 4.15E-05 19/28 K.VSALDLAVLDQVEAR.L "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 6 1597.8675 3.89 25900 21033 2 1597.869672 799.941 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.03 3862.7 - 728384 - - - 1.3368 - 3.523 0.448 - 1544.6 1 2 0 0.0021 15 0 0 0 3.36E+06 8.62E+05 - - - 5.4453 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.21034.21034.2 0.00442 18-Sep K.VVLPTFILEK[136.11].R "sp|Q9BXB5|OSB10_HUMAN,sp|Q9BXB4|OSB11_HUMAN,tr|H7C487|H7C487_HUMAN,tr|A0A5F9ZH75|A0A5F9ZH75_HUMAN" 4 1165.7202 -1 25901 21034 2 1165.723479 583.8674 Oxysterol-binding protein-related protein 10 OS=Homo sapiens OX=9606 GN=OSBPL10 PE=1 SV=2 5.97 3862.8 - 716853 - - - 2.8154 - 1.621 0.32 - 176.5 1 2 0 0.0033 10 0 0 0 0.00E+00 0.00E+00 - - - 2.7518 1 230117_WJC_METTL3_WT_vs_EV_F03.21039.21039.2 4.52E-08 18/28 R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 3.47 25905 21039 2 1710.909253 856.4607 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3863.3 - 2.66E+06 - - - 1.4501 - 3.524 0.58 - 881 1 2 0 0.0025 15 0 0 0 6.37E+08 1.84E+08 - - - 6.4209 1 230117_WJC_METTL3_WT_vs_EV_F03.21041.21041.2 1.92E-06 14/26 K.LFIYNPTTGEFLGR.T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1626.8406 1.65 25907 21041 2 1626.841077 814.4276 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3863.4 - 1.14E+06 - - - 0.2975 - 2.321 0.477 - 490.6 1 2 0 0.0005 14 0 0 0 3.33E+07 2.02E+07 - - - 4.6769 1 230117_WJC_METTL3_WT_vs_EV_F03.21042.21042.2 2.35E-07 13/22 R.LEGLTDEINFLR[166.11].Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1428.7488 1.89 25908 21042 2 1428.751036 715.3817 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3863.5 - 1.10E+06 - - - 1.5545 - 2.773 0.529 - 730.5 1 2 0 0.0022 12 0 0 0 2.33E+07 1.24E+07 - - - 5.6311 1 230117_WJC_METTL3_WT_vs_EV_F03.21043.21043.2 1.25E-05 26-Dec K.LFIYNPTTGEFLGR[166.11].T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1636.8489 1.65 25909 21043 2 1636.853138 819.4317 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3863.6 - 990245 - - - 2.6117 - 1.875 0.562 - 302 1 2 0 0.0043 14 0 0 0 3.33E+07 2.02E+07 - - - 4.7681 1 230117_WJC_METTL3_WT_vs_EV_F03.21045.21045.2 3.36E-05 14/26 R.VLLATLSIPITPER.T sp|Q14152|EIF3A_HUMAN 1 1521.913 1.04 25911 21045 2 1521.915443 761.9638 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3863.8 - 697983 - - - 1.5855 - 2.801 0.493 - 420.2 1 2 0 0.0024 14 0 0 0 5.71E+07 5.48E+07 - - - 5.2662 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21053.21053.2 0.0003 18-Sep R.MIYLQTLLAK.E sp|P11274|BCR_HUMAN 1 1192.689 8.02 25919 21053 2 1192.691676 597.3518 Breakpoint cluster region protein OS=Homo sapiens OX=9606 GN=BCR PE=1 SV=2 8.34 3864.8 - 167020 - - - 2.2713 - 1.914 0.391 - 203.2 1 2 0 0.0027 10 0 0 0 1.71E+06 2.13E+05 - - - 3.7402 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.21059.21059.2 4.64E-05 20-Oct R.GVTFLFPIQAK.T sp|Q9NR30|DDX21_HUMAN 1 1219.6965 0.94 25924 21059 2 1219.699854 610.8555 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3865.6 - 852492 - - - 2.754 - 2.042 0.323 - 398.4 1 2 0 0.0034 11 0 0 0 1.24E+08 1.32E+08 - - - 3.357 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.21063.21063.2 0.0897 14-Jul R.EGLLAIFK[136.11].S "sp|P35222|CTNB1_HUMAN,sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|C9J826|C9J826_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 15 897.5415 6.12 25928 21063 2 897.542651 449.778 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 6.1 3865.9 - 225684 - - - 1.2779 - 1.432 0.264 - 139.1 1 2 0 0.0011 8 0 0 0 2.49E+07 4.07E+06 - - - 2.0735 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21066.21066.2 0.00581 18-Oct K.FSLFAGGMLR.V sp|Q9BVK6|TMED9_HUMAN 1 1097.5692 1.28 25929 21066 2 1097.570028 549.7919 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 9.75 3866.3 - 308999 - - - 0.7671 - 2.034 0.34 - 370.7 1 2 0 0.0008 10 0 0 0 1.70E+07 1.32E+07 - - - 3.5338 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21067.21067.2 0.000235 18-Sep K.FEELNMDLFR.S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1312.6122 4.45 25930 21067 2 1312.612664 657.3134 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.14 3866.4 - 150666 - - - 0.3741 - 2.061 0.398 - 307.5 1 2 0 0.0005 10 0 0 0 5.91E+07 1.33E+07 - - - 3.9991 0.999 230117_WJC_METTL3_WT_vs_EV_F03.21068.21068.2 0.00183 14-Sep R.FPLFGGWK.T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 950.5014 1.61 25931 21068 2 950.504436 476.258 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3866.4 - 510025 - - - 3.1689 - 1.575 0.384 - 270 1 2 0 0.003 8 0 0 0 3.65E+07 2.26E+07 - - - 3.2463 0.9112 230117_WJC_METTL3_WT_vs_EV_F03.21069.21069.2 0.0574 12-Jul Y.SSFLFWR.M sp|Q13015|AF1Q_HUMAN 1 941.4759 3.66 25932 21069 2 941.475727 471.7452 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 9.47 3866.5 - 385938 - - - -0.2241 - 1.653 0.284 - 189.1 1 1 0 -0.0002 7 0 0 0 4.95E+06 1.35E+06 - - - 2.731 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21072.21072.2 0.00124 18-Jul K.YLMIEEYLTK.E sp|O95817|BAG3_HUMAN 1 1301.6577 5.86 25935 21072 2 1301.658316 651.8361 BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3 4.53 3866.7 - 97537.4 - - - 0.4533 - 1.392 0.503 - 133.8 1 2 0 0.0006 10 0 0 0 4.57E+06 7.80E+05 - - - 3.6792 1 230117_WJC_METTL3_WT_vs_EV_F03.21077.21077.2 9.44E-07 26-Sep R.ILGIPVIVTEQYPK.G "sp|Q96CN7|ISOC1_HUMAN,tr|D6RGE2|D6RGE2_HUMAN" 2 1568.9178 1.66 25940 21077 2 1568.923648 785.4662 Isochorismatase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ISOC1 PE=1 SV=3 6 3867.3 - 0 - - - 3.7395 - 1.94 0.533 - 188.7 1 2 0 0.0059 14 0 0 0 4.91E+06 2.95E+06 - - - 4.6389 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.21078.21078.3 0.0142 Oct-44 R.LLALLDALASHK[136.11].A "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 1271.7693 1.82 25941 21078 3 1271.766466 424.9304 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6.74 3867.4 - 89219.6 - - - -2.2072 - 1.922 0.406 - 149.5 1 2 0 -0.0028 12 0 0 0 8.15E+06 4.46E+06 - - - 4.8768 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21082.21082.2 0.000852 20-Nov R.GVTFLFPIQAK[136.11].T sp|Q9NR30|DDX21_HUMAN 1 1227.7107 0.97 25943 21082 2 1227.71244 614.8626 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3868 - 2.17E+07 - - - 1.4213 - 2.185 0.325 - 420 1 2 0 0.0017 11 0 0 0 1.24E+08 1.28E+08 - - - 3.5554 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.21083.21083.2 0.000287 20-Sep K.SGAYLIPLLER[166.11].L "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1240.7055 1.22 25944 21083 2 1240.706644 621.36 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.72 3868 - 1.98E+07 - - - 0.9277 - 1.914 0.25 - 266.3 1 2 0 0.0011 11 0 0 0 2.27E+08 1.86E+08 - - - 2.6434 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21085.21085.2 0.00418 16-Sep R.IIFVDEVFK[136.11].L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1116.631 2.51 25946 21085 2 1116.631321 559.3228 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 4.37 3868.1 - 6.07E+06 - - - 0.2445 - 1.95 0.474 - 209.5 1 2 0 0.0003 9 0 0 0 4.12E+07 1.64E+07 - - - 4.4739 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.21086.21086.3 0.000317 Nov-52 K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 14.18 25947 21086 3 1621.814913 541.6124 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3868.2 - 3.71E+06 - - - -0.2362 - 1.837 0.473 - 159.4 1 2 0 -0.0004 14 0 0 0 4.30E+08 3.03E+07 - - - 5.4295 0.999 230117_WJC_METTL3_WT_vs_EV_F03.21087.21087.3 0.00536 14/44 R.LLALLDALASHK.A "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 1263.7551 1.83 25948 21087 3 1263.753497 422.259 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6.74 3868.3 - 3.33E+06 - - - -1.2471 - 2.891 0.24 - 330.7 1 2 0 -0.0016 12 0 0 0 8.16E+06 4.46E+06 - - - 4.1579 1 230117_WJC_METTL3_WT_vs_EV_F03.21088.21088.2 2.03E-05 14/26 R.DYGVLLEGSGLALR[166.11].G sp|P30048|PRDX3_HUMAN 1 1471.791 1.35 25949 21088 2 1471.791668 736.9028 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 4.37 3868.4 - 2.88E+06 - - - 0.4444 - 2.822 0.518 - 647.9 1 2 0 0.0007 14 0 0 0 1.55E+07 1.15E+07 - - - 5.4702 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21093.21093.2 2.32E-05 26-Oct R.VFGAPEVLENLEVK[136.11].S sp|Q8TEM1|PO210_HUMAN 1 1550.8436 2.13 25954 21093 2 1550.844258 776.4291 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.25 3869 - 1.38E+06 - - - 0.4501 - 1.894 0.486 - 218.7 1 2 0 0.0007 14 0 0 0 6.42E+06 3.02E+06 - - - 4.2331 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.21095.21095.2 0.0806 20-Aug K.IALGIPLPEIK.N "sp|P31327|CPSM_HUMAN,tr|A0A669KBF2|A0A669KBF2_HUMAN" 2 1162.7325 2.14 25956 21095 2 1162.733391 582.3735 "Carbamoyl-phosphate synthase [ammonia], mitochondrial OS=Homo sapiens OX=9606 GN=CPS1 PE=1 SV=2" 6 3869.3 - 1.30E+06 - - - 0.7267 - 1.809 0.193 - 130.7 1 2 0 0.0008 11 0 0 0 4.01E+06 1.87E+06 - - - 2.0698 0.9006 230117_WJC_METTL3_WT_vs_EV_F03.21098.21098.2 2.49 14-Apr R.SFTNQIIL.- "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIM4|A0A804HIM4_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 3 934.5124 - 25959 21098 2 934.511978 468.2635 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 5.24 3869.7 - 1.10E+06 - - - -0.4334 - 0.796 0.134 - 31.3 1 2 0 -0.0004 8 0 0 0 - - - - - -0.6575 1 230117_WJC_METTL3_WT_vs_EV_F03.21099.21099.2 0.000365 24-Nov R.APLPDLYPFGTMR[166.11].G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1486.7518 2.1 25960 21099 2 1486.754311 744.3832 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3869.8 - 1.08E+06 - - - 1.6943 - 2.096 0.524 - 372.3 1 2 0 0.0025 13 0 0 0 1.47E+07 6.97E+06 - - - 4.8098 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21100.21100.2 0.00859 24-Dec M.PGIVELPTLEELK.V sp|P51970|NDUA8_HUMAN 1 1436.8126 1.63 25961 21100 2 1436.813797 719.4136 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 4.25 3869.9 - 1.04E+06 - - - 0.8004 - 2.167 0.421 - 366.2 1 2 0 0.0011 13 0 0 0 2.43E+06 1.49E+06 - - - 4.135 0.9889 230117_WJC_METTL3_WT_vs_EV_F03.21104.21104.2 0.000406 18-Sep R.YVLGMQELFR[166.11].G "sp|Q96J01|THOC3_HUMAN,tr|D6RGZ2|D6RGZ2_HUMAN" 2 1264.6513 0.83 25964 21104 2 1264.645433 633.333 THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1 6 3870.5 - 44278.7 - - - -4.678 - 1.769 0.394 - 264.5 1 2 0 -0.0059 10 0 0 0 1.25E+07 1.51E+07 - - - 3.5414 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21107.21107.2 0.000153 14-Aug R.GFVFITFK[136.11].E "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 965.5466 0.76 25967 21107 2 965.54824 483.7806 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3870.9 - 116200 - - - 1.7089 - 1.634 0.444 - 284.9 1 2 0 0.0017 8 0 0 0 2.14E+07 2.82E+07 - - - 3.8008 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.21113.21113.2 0.000884 16-Aug R.IIFVDEVFK.L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1108.6168 2.51 25971 21113 2 1108.618609 555.3157 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 4.37 3871.7 - 3.87E+06 - - - 1.5885 - 1.672 0.357 - 139.7 1 2 0 0.0018 9 0 0 0 4.12E+07 1.64E+07 - - - 3.1643 0.9906 230117_WJC_METTL3_WT_vs_EV_F03.21114.21114.2 0.000413 14-Sep R.FPLFGGWK[136.11].T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 958.5156 1.64 25972 21114 2 958.511788 480.2651 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3871.8 - 2.90E+06 - - - -4.002 - 1.574 0.372 - 246.5 1 2 0 -0.0038 8 0 0 0 2.87E+07 1.75E+07 - - - 3.1555 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.21115.21115.2 0.00713 18-Oct K.FEELNMDLFR[166.11].S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1322.6204 4.31 25973 21115 2 1322.620572 662.3175 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.14 3871.9 - 2.33E+06 - - - 0.0975 - 2.18 0.348 - 344.6 1 2 0 0.0001 10 0 0 0 5.92E+07 1.37E+07 - - - 3.7866 0.8732 230117_WJC_METTL3_WT_vs_EV_F03.21116.21116.2 0.485 16-Sep N.ILLVDEIMR.A "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1100.6264 0.36 25974 21116 2 1100.627965 551.3205 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 4.37 3872 - 2.21E+06 - - - 1.4519 - 1.696 0.167 - 178 1 1 0 0.0016 9 0 0 0 1.06E+07 2.93E+07 - - - 1.8023 1 230117_WJC_METTL3_WT_vs_EV_F03.21117.21117.2 0.000147 20-Nov R.SGIVEYLSLVK.G "sp|P49642|PRI1_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN,tr|F8VNY2|F8VNY2_HUMAN" 3 1206.686 1.91 25975 21117 2 1206.689016 604.3503 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 5.72 3872.1 - 1.87E+06 - - - 2.5077 - 2.217 0.477 - 280.3 1 2 0 0.003 11 0 0 0 1.01E+07 5.29E+06 - - - 4.717 1 230117_WJC_METTL3_WT_vs_EV_F03.21119.21119.2 0.00124 20-Dec K.LSDLDYMQFIR.L sp|P82933|RT09_HUMAN 1 1399.6806 0.99 25977 21119 2 1399.680844 700.8476 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.21 3872.4 - 1.64E+06 - - - 0.1836 - 2.857 0.393 - 908.7 1 2 0 0.0003 11 0 0 0 1.29E+07 1.30E+07 - - - 4.7835 1 230117_WJC_METTL3_WT_vs_EV_F03.21120.21120.2 0.000183 13/22 K.LADFALLC[160.03]LDGK.R "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 1334.6904 999 25978 21120 2 1334.687537 668.3525 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 4.21 3872.5 - 1.10E+06 - - - -2.163 - 3.018 0.479 - 831 1 2 0 -0.0029 12 0 0 0 5.69E+06 0.00E+00 - - - 5.4844 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.21122.21122.2 5.40E-07 24-Sep R.APLPDLYPFGTMR.G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1476.7435 2.05 25980 21122 2 1476.741648 739.379 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3872.8 - 986053 - - - -1.269 - 1.941 0.481 - 211.6 1 2 0 -0.0019 13 0 0 0 1.47E+07 7.15E+06 - - - 4.2952 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.21128.21128.2 0.00374 20-Oct K.TLDVFNITIAR[166.11].Q sp|Q96RL7|VP13A_HUMAN 1 1271.7113 0.57 25986 21128 2 1271.709827 636.8629 Vacuolar protein sorting-associated protein 13A OS=Homo sapiens OX=9606 GN=VPS13A PE=1 SV=2 5.5 3873.6 - 364022 - - - -1.1638 - 1.929 0.33 - 196.9 1 2 0 -0.0015 11 0 0 0 1.48E+06 2.60E+06 - - - 3.2553 1 230117_WJC_METTL3_WT_vs_EV_F03.21129.21129.2 5.99E-10 20/36 R.LAESLLALSQQEELADLPK.D sp|Q9BVJ6|UT14A_HUMAN 1 2067.11 1.15 25987 21129 2 2067.108338 1034.5623 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4 3873.7 - 338818 - - - -0.7808 - 4.228 0.647 - 1469.3 1 2 0 -0.0016 19 0 0 0 1.21E+06 1.05E+06 - - - 7.3638 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.21134.21134.2 0.0024 22-May R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 25990 21134 2 1603.765329 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3874.4 - 5.87E+07 - - - 0.8661 - 1.24 0.403 - 74.9 1 2 0 0.0014 12 0 0 0 2.66E+09 0.00E+00 - - - 2.5831 1 230117_WJC_METTL3_WT_vs_EV_F03.21135.21135.2 6.09E-07 15/26 R.VLLATLSIPITPER[166.11].T sp|Q14152|EIF3A_HUMAN 1 1531.9213 1.04 25991 21135 2 1531.923861 766.9679 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3874.5 - 1.56E+06 - - - 1.6718 - 2.84 0.499 - 658.4 1 2 0 0.0026 14 0 0 0 5.71E+07 5.48E+07 - - - 5.3452 1 230117_WJC_METTL3_WT_vs_EV_F03.21139.21139.2 1.37E-07 14/26 R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 26.75 25995 21139 2 1581.811976 791.9109 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3874.9 - 406257 - - - 2.9915 - 3.05 0.639 - 536.9 1 2 0 0.0047 14 0 0 0 1.45E+07 5.41E+05 - - - 6.5576 0.9001 230117_WJC_METTL3_WT_vs_EV_F03.21140.21140.2 1.51 26-Jun R.AAAASDFTC[160.03]ASTSR.S sp|P49640|EVX1_HUMAN 1 1414.6147 999 25996 21140 2 1414.613548 708.3146 Homeobox even-skipped homolog protein 1 OS=Homo sapiens OX=9606 GN=EVX1 PE=2 SV=1 5.87 3875.1 - 351376 - - - -0.8094 - 1.04 0.065 - 59 2 2 0 -0.0011 14 0 0 0 2.58E+07 0.00E+00 - - - -0.5153 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.21142.21142.2 0.291 16-Aug K.TTPLLSFLK[136.11].N sp|Q9BZI7|REN3B_HUMAN 1 1026.6205 0.87 25998 21142 2 1026.622936 514.3175 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 8.41 3875.3 - 290279 - - - 2.3894 - 1.512 0.189 - 223.1 1 2 0 0.0025 9 0 0 0 1.00E+07 1.16E+07 - - - 1.6323 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.21143.21143.2 0.00574 20-Sep K.NVPGLAILLSK.D sp|Q9BUL9|RPP25_HUMAN 1 1123.6965 1.37 25999 21143 2 1123.700061 562.8555 Ribonuclease P protein subunit p25 OS=Homo sapiens OX=9606 GN=RPP25 PE=1 SV=1 8.75 3875.4 - 210523 - - - 3.1735 - 1.472 0.363 - 178.5 1 2 0 0.0036 11 0 0 0 7.00E+06 5.11E+06 - - - 2.7669 1 230117_WJC_METTL3_WT_vs_EV_F03.21144.21144.2 4.83E-08 22-Dec K.VDALMDEINFMK.M "sp|P13647|K2C5_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 2 1424.668 999 26000 21144 2 1424.667889 713.3413 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.03 3875.6 - 205513 - - - -0.059 - 2.697 0.649 - 487.7 1 2 0 -0.0001 12 0 0 0 2.32E+07 0.00E+00 - - - 6.445 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.21149.21149.3 9.49E-06 14/52 R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 11.22 26005 21149 3 1581.80688 528.2764 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3876.2 - 110091 - - - -0.2301 - 2.682 0.515 - 293.2 1 2 0 -0.0004 14 0 0 0 3.48E+06 3.10E+05 - - - 6.9035 0.9856 230117_WJC_METTL3_WT_vs_EV_F03.21152.21152.2 0.0206 28-Jun K.LYLAPLTTC[160.03]GNLPFR[166.11].R sp|Q96G46|DUS3L_HUMAN 1 1744.921 -1 26008 21152 2 1744.916912 873.4678 tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like OS=Homo sapiens OX=9606 GN=DUS3L PE=1 SV=2 8.22 3876.6 - 45115.9 - - - -2.3331 - 1.345 0.248 - 74.7 1 2 0 -0.0041 15 0 0 0 0.00E+00 0.00E+00 - - - 1.6001 1 230117_WJC_METTL3_WT_vs_EV_F03.21156.21156.2 8.18E-07 24-Dec R.LLSFSPEEFPTLK.A sp|Q5JSZ5|PRC2B_HUMAN 1 1506.797 1.48 26011 21156 2 1506.801056 754.4058 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3877 - 2.08E+06 - - - 2.6938 - 2.497 0.564 - 480.8 1 2 0 0.0041 13 0 0 0 2.43E+07 1.64E+07 - - - 5.554 0.9675 230117_WJC_METTL3_WT_vs_EV_F03.21157.21157.2 9.96E-05 24-Jul R.LLSFSPEEFPTLK[136.11].A sp|Q5JSZ5|PRC2B_HUMAN 1 1514.8112 1.43 26012 21157 2 1514.821552 758.4129 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3877 - 1.66E+06 - - - 6.8358 - 1.553 0.253 - 114.5 1 2 0 0.0104 13 0 0 0 2.35E+07 1.64E+07 - - - 2.0362 1 230117_WJC_METTL3_WT_vs_EV_F03.21159.21159.2 3.47E-08 24-Dec R.ELPTAFDYVEFTR[166.11].S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1596.7699 1.03 26014 21159 2 1596.773828 799.3922 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.14 3877.2 - 1.26E+06 - - - 2.4324 - 2.512 0.542 - 687.5 1 2 0 0.0039 13 0 0 0 9.58E+06 9.29E+06 - - - 5.407 1 230117_WJC_METTL3_WT_vs_EV_F03.21162.21162.2 2.03E-05 24-Dec R.ELYAFFGDSLATR.F sp|Q9Y6J9|TAF6L_HUMAN 1 1488.7249 0.94 26017 21162 2 1488.726565 745.3697 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4.37 3877.3 - 839829 - - - 1.1218 - 2.294 0.541 - 469 1 2 0 0.0017 13 0 0 0 5.20E+06 5.53E+06 - - - 5.1673 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.21166.21166.2 0.0166 20-Sep R.SIFTGLMIDPR.T sp|Q8IWA0|WDR75_HUMAN 1 1248.6536 1.66 26021 21166 2 1248.657294 625.3341 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 5.55 3877.6 - 534996 - - - 2.9231 - 1.707 0.307 - 200 1 2 0 0.0037 11 0 0 0 5.53E+06 3.33E+06 - - - 2.7539 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21168.21168.2 0.000885 22-Oct K.LTAYAMTIPFVR.Q "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1381.7428 1.34 26023 21168 2 1381.746766 691.8787 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 3877.7 - 512340 - - - 2.8754 - 2.218 0.449 - 457.3 1 2 0 0.004 12 0 0 0 3.05E+06 2.28E+06 - - - 4.4521 1 230117_WJC_METTL3_WT_vs_EV_F03.21169.21169.2 5.12E-11 13/28 K.LLMSEDYFTQAMEVK.A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1803.8423 1.03 26024 21169 2 1803.844285 902.9284 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.14 3877.9 - 317276 - - - 1.0954 - 3.073 0.602 - 411.9 1 2 0 0.002 15 0 0 0 1.40E+06 1.36E+06 - - - 6.2468 1 230117_WJC_METTL3_WT_vs_EV_F03.21170.21170.2 1.52E-11 14/28 K.LLMSEDYFTQAMEVK[136.11].A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1811.8565 -1 26025 21170 2 1811.860422 906.9355 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.14 3878 - 304445 - - - 2.1597 - 3.174 0.67 - 536.7 1 2 0 0.0039 15 0 0 0 0.00E+00 0.00E+00 - - - 6.828 0.995 230117_WJC_METTL3_WT_vs_EV_F03.21171.21171.2 0.0015 20-Nov R.WPDPEDLLTPR[166.11].W sp|Q8TAE8|G45IP_HUMAN 1 1347.6698 1.85 26026 21171 2 1347.66572 674.8422 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.03 3878.1 - 290797 - - - -3.0542 - 1.872 0.334 - 378.5 1 2 0 -0.0041 11 0 0 0 1.19E+07 6.40E+06 - - - 3.2028 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.21173.21173.3 0.064 Sep-56 R.RFPVAPLIPYPLITK.E "sp|P49756|RBM25_HUMAN,tr|H0YE46|H0YE46_HUMAN" 2 1724.0389 1.89 26028 21173 3 1724.041551 575.6869 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 9.99 3878.2 - 196158 - - - 1.5382 - 1.63 0.283 - 60 1 2 0 0.0027 15 0 0 0 6.50E+05 3.44E+05 - - - 2.9693 0.9953 230117_WJC_METTL3_WT_vs_EV_F03.21181.21181.2 0.141 16-Jun K.TTPLLSFLK.N sp|Q9BZI7|REN3B_HUMAN 1 1018.6063 0.87 26034 21181 2 1018.610243 510.3104 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 8.41 3879.1 - 436362 - - - 3.8877 - 1.291 0.304 - 117.7 1 2 0 0.004 9 0 0 0 1.00E+07 1.16E+07 - - - 2.024 0.9374 230117_WJC_METTL3_WT_vs_EV_F03.21183.21183.2 0.532 Jun-32 R.ASSGGGAGGAAGYAPVK.Y sp|P25067|CO8A2_HUMAN 1 1376.6684 2.8 26036 21183 2 1376.666472 689.3415 Collagen alpha-2(VIII) chain OS=Homo sapiens OX=9606 GN=COL8A2 PE=1 SV=2 8.63 3879.3 - 403516 - - - -1.431 - 1.194 0.079 - 52.5 1 2 0 -0.002 17 0 0 0 3.66E+06 1.31E+06 - - - 0.0598 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21185.21185.2 0.000336 16-Sep K.AFVPAILFK[136.11].D sp|Q9HAU5|RENT2_HUMAN 1 1012.6201 0.99 26038 21185 2 1012.621557 507.3173 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3879.4 - 293416 - - - 1.4497 - 1.765 0.46 - 313.2 1 2 0 0.0015 9 0 0 0 3.54E+06 3.57E+06 - - - 4.0818 1 230117_WJC_METTL3_WT_vs_EV_F03.21190.21190.2 1.31E-07 13/26 R.ILSVQGTEPLVLFK.E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1542.9021 1.28 26043 21190 2 1542.90613 772.4583 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3879.8 - 288112 - - - 2.5919 - 2.536 0.598 - 538.6 1 2 0 0.004 14 0 0 0 6.90E+06 5.40E+06 - - - 5.7918 1 230117_WJC_METTL3_WT_vs_EV_F03.21191.21191.2 2.14E-07 26-Nov R.ILSVQGTEPLVLFK[136.11].E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1550.9163 1.28 26044 21191 2 1550.919817 776.4654 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3880 - 56681.9 - - - 2.2477 - 2.367 0.531 - 390.6 1 2 0 0.0035 14 0 0 0 6.90E+06 5.40E+06 - - - 5.1241 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21192.21192.2 0.00116 18-Oct R.LLEVYDQLFK.S "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1266.686 2.51 26045 21192 2 1266.688765 634.3503 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3880 - 93012.9 - - - 2.1908 - 2.172 0.454 - 314.5 1 2 0 0.0028 10 0 0 0 6.80E+06 2.71E+06 - - - 4.5584 1 230117_WJC_METTL3_WT_vs_EV_F03.21195.21195.2 5.71E-08 22-Dec K.VMEETLSYLLGR.K "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN,tr|A0A5F9ZH78|A0A5F9ZH78_HUMAN" 3 1409.7225 22.01 26048 21195 2 1409.732147 705.8685 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 4.53 3880.4 - 69316.4 - - - 6.8772 - 2.44 0.629 - 533.9 1 2 0 0.0097 12 0 0 0 2.46E+06 1.12E+05 - - - 6.0307 1 230117_WJC_METTL3_WT_vs_EV_F03.21196.21196.2 8.85E-05 24-Nov K.IISLDLPVAEVYK[136.11].K "sp|Q5T4S7|UBR4_HUMAN,tr|X6R960|X6R960_HUMAN" 2 1466.8476 -1 26049 21196 2 1466.848204 734.4311 E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1 4.37 3880.5 - 96588.3 - - - 0.4234 - 2.219 0.481 - 257.4 1 2 0 0.0006 13 0 0 0 0.00E+00 0.00E+00 - - - 4.6391 1 230117_WJC_METTL3_WT_vs_EV_F03.21201.21201.2 1.28E-06 13/26 R.ILSVQGTEPLVLFK[136.11].E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1550.9163 1.28 26053 21201 2 1550.920724 776.4654 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3881.2 - 1.70E+06 - - - 2.8325 - 2.52 0.515 - 519.7 1 2 0 0.0044 14 0 0 0 6.90E+06 5.40E+06 - - - 5.1628 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.21204.21204.2 0.00109 16-Sep K.AFVPAILFK.D sp|Q9HAU5|RENT2_HUMAN 1 1004.6059 1.01 26056 21204 2 1004.608947 503.3102 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3881.6 - 1.26E+06 - - - 3.044 - 1.653 0.404 - 249.7 1 2 0 0.0031 9 0 0 0 3.54E+06 3.51E+06 - - - 3.478 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.21207.21207.2 0.00248 20-Oct K.NVPGLAILLSK[136.11].D sp|Q9BUL9|RPP25_HUMAN 1 1131.7107 1.49 26059 21207 2 1131.714248 566.8626 Ribonuclease P protein subunit p25 OS=Homo sapiens OX=9606 GN=RPP25 PE=1 SV=1 8.75 3882 - 589026 - - - 3.1395 - 2.068 0.433 - 253.2 1 2 0 0.0036 11 0 0 0 1.27E+06 8.53E+05 - - - 4.2036 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.21208.21208.2 4.14E-06 13/26 K.TGAAGAEALSLLLK.R "sp|Q9P2N6|KANL3_HUMAN,tr|C9J5A4|C9J5A4_HUMAN,tr|A0A590UJ53|A0A590UJ53_HUMAN" 3 1313.7555 -1 26060 21208 2 1313.759962 657.885 KAT8 regulatory NSL complex subunit 3 OS=Homo sapiens OX=9606 GN=KANSL3 PE=1 SV=2 5.66 3882.1 - 564156 - - - 3.4215 - 2.506 0.395 - 488.8 1 2 0 0.0045 14 0 0 0 0.00E+00 0.00E+00 - - - 4.2625 1 230117_WJC_METTL3_WT_vs_EV_F03.21210.21210.2 3.99E-06 20/26 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.47 26062 21210 2 1672.884924 837.4479 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3882.4 - 551634 - - - 2.2106 - 3.479 0.584 - 1652.8 1 2 0 0.0037 14 0 0 0 9.58E+07 2.02E+08 - - - 6.4819 0.9114 230117_WJC_METTL3_WT_vs_EV_F03.21213.21213.2 0.402 20-Jun R.SIFTGLMIDPR[166.11].T sp|Q8IWA0|WDR75_HUMAN 1 1258.6619 1.66 26065 21213 2 1258.665979 630.3382 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 5.55 3882.8 - 443497 - - - 3.2296 - 1.33 0.051 - 69.7 37 2 0 0.0041 11 0 0 0 5.53E+06 3.33E+06 - - - -0.5126 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21214.21214.2 2.12E-06 24-Nov K.IISLDLPVAEVYK.K "sp|Q5T4S7|UBR4_HUMAN,tr|X6R960|X6R960_HUMAN" 2 1458.8334 -1 26066 21214 2 1458.837611 730.424 E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1 4.37 3882.9 - 430199 - - - 2.8982 - 2.04 0.498 - 294.7 1 2 0 0.0042 13 0 0 0 0.00E+00 0.00E+00 - - - 4.5477 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.21216.21216.2 0.0856 22-Sep K.LTAYAMTIPFVR[166.11].Q "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1391.7511 1.34 26068 21216 2 1391.754742 696.8828 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 3883.2 - 322781 - - - 2.6434 - 1.581 0.285 - 202.3 1 2 0 0.0037 12 0 0 0 3.05E+06 2.28E+06 - - - 2.3501 1 230117_WJC_METTL3_WT_vs_EV_F03.21222.21222.3 5.31E-09 19/52 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.54 26073 21222 3 1672.884279 558.6344 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3883.7 - 1.33E+06 - - - 1.825 - 3.447 0.56 - 609.2 1 2 0 0.0031 14 0 0 0 4.15E+07 7.73E+07 - - - 8.0713 1 230117_WJC_METTL3_WT_vs_EV_F03.21224.21224.3 8.50E-07 15/52 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.55 26075 21224 3 1662.875651 555.2983 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3883.8 - 537869 - - - 1.6207 - 3.122 0.527 - 374.8 1 2 0 0.0027 14 0 0 0 4.24E+07 7.73E+07 - - - 7.4403 1 230117_WJC_METTL3_WT_vs_EV_F03.21225.21225.2 4.28E-08 18/26 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.47 26076 21225 2 1662.874458 832.4438 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3883.9 - 528597 - - - 0.9033 - 3.305 0.567 - 1408.7 1 2 0 0.0015 14 0 0 0 9.58E+07 2.02E+08 - - - 6.2283 1 230117_WJC_METTL3_WT_vs_EV_F03.21226.21226.2 4.53E-08 24-Dec R.VVSTFGVIFDPVK.Q sp|Q9P2D1|CHD7_HUMAN 1 1406.781 0.93 26077 21226 2 1406.783806 704.3978 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 5.81 3883.9 - 332213 - - - 2.028 - 2.324 0.589 - 377.6 1 2 0 0.0029 13 0 0 0 9.25E+06 9.91E+06 - - - 5.5548 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.21228.21228.2 0.0978 14-Jun R.LQWWDFTK.F "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1122.5498 1.71 26079 21228 2 1122.551534 562.2822 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 5.84 3884.1 - 287920 - - - 1.5171 - 1.296 0.277 - 98.1 1 2 0 0.0017 8 0 0 0 1.33E+06 7.82E+05 - - - 1.8684 1 230117_WJC_METTL3_WT_vs_EV_F03.21229.21229.2 6.47E-07 22-Oct R.LIMNYLVTEGFK.E sp|Q9NWU2|GID8_HUMAN 1 1426.753 1.27 26080 21229 2 1426.755401 714.3838 Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1 6 3884.1 - 206950 - - - 1.666 - 2.116 0.564 - 302.8 1 2 0 0.0024 12 0 0 0 5.82E+06 4.59E+06 - - - 5.1781 1 230117_WJC_METTL3_WT_vs_EV_F03.21233.21233.2 6.64E-08 30-Nov R.LFVGNLPADITEDEFK.R sp|P23246|SFPQ_HUMAN 1 1806.904 -1 26084 21233 2 1806.910161 904.4593 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3884.6 - 0 - - - 3.4202 - 2.526 0.55 - 148.5 1 2 0 0.0062 16 0 0 0 0.00E+00 0.00E+00 - - - 5.3795 1 230117_WJC_METTL3_WT_vs_EV_F03.21235.21235.2 1.81E-06 30-Nov R.LFVGNLPADITEDEFK[136.11].R sp|P23246|SFPQ_HUMAN 1 1814.9182 1.22 26086 21235 2 1814.921136 908.4664 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3884.9 - 60647.1 - - - 1.6282 - 2.403 0.558 - 186.8 1 2 0 0.003 16 0 0 0 6.72E+05 5.51E+05 - - - 5.3169 1 230117_WJC_METTL3_WT_vs_EV_F03.21239.21239.2 3.75E-08 16/26 K.LFSLELVDESGEIR[166.11].A sp|P27694|RFA1_HUMAN 1 1615.8333 0.13 26088 21239 2 1615.832657 808.9239 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4 3885.5 - 4.90E+06 - - - -0.3812 - 3.059 0.563 - 1179.6 1 2 0 -0.0006 14 0 0 0 1.36E+07 1.02E+08 - - - 6.0049 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21240.21240.2 0.00798 13/22 R.GLFIIDPNGVIK.H sp|P30048|PRDX3_HUMAN 1 1284.7442 2.21 26089 21240 2 1284.747266 643.3794 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3885.5 - 1.67E+06 - - - 2.4067 - 2.288 0.376 - 446.2 1 2 0 0.0031 12 0 0 0 9.19E+07 4.16E+07 - - - 3.9949 1 230117_WJC_METTL3_WT_vs_EV_F03.21241.21241.2 0.000175 18-Sep K.DAITQALFLR.E sp|Q9UNX4|WDR3_HUMAN 1 1146.6397 1.14 26090 21241 2 1146.640794 574.3271 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.84 3885.6 - 1.68E+06 - - - 0.9471 - 2.198 0.498 - 244 1 2 0 0.0011 10 0 0 0 4.01E+07 3.52E+07 - - - 4.9172 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21242.21242.2 0.000593 18-Sep K.DAITQALFLR[166.11].E sp|Q9UNX4|WDR3_HUMAN 1 1156.648 1.14 26091 21242 2 1156.649194 579.3313 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.84 3885.7 - 1.48E+06 - - - 1.0513 - 2.265 0.377 - 236.4 1 2 0 0.0012 10 0 0 0 4.01E+07 3.52E+07 - - - 4.1072 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21245.21245.2 0.00107 22-Dec R.GLFIIDPNGVIK[136.11].H sp|P30048|PRDX3_HUMAN 1 1292.7584 2.21 26094 21245 2 1292.759828 647.3865 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3885.9 - 658423 - - - 1.1247 - 2.106 0.34 - 364.1 1 2 0 0.0015 12 0 0 0 9.19E+07 4.16E+07 - - - 3.5115 1 230117_WJC_METTL3_WT_vs_EV_F03.21246.21246.3 2.94E-06 Dec-40 R.SIIGMIDMFHK.Y "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1290.6464 490.71 26095 21246 3 1290.648763 431.2228 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.46 3886 - 538607 - - - 1.7921 - 2.213 0.55 - 127.8 1 2 0 0.0023 11 0 0 0 1.54E+07 3.13E+04 - - - 6.9279 1 230117_WJC_METTL3_WT_vs_EV_F03.21247.21247.2 8.12E-06 13/20 K.TITAYFGDLIR[166.11].R sp|Q96RS0|TGS1_HUMAN 1 1278.6848 1.71 26096 21247 2 1278.685996 640.3497 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 5.5 3886.1 - 390487 - - - 0.9682 - 2.353 0.574 - 495 1 2 0 0.0012 11 0 0 0 1.71E+07 1.00E+07 - - - 5.595 1 230117_WJC_METTL3_WT_vs_EV_F03.21249.21249.2 0.000534 15/20 R.LTGLLDLALEK.D sp|P04746|AMYP_HUMAN 1 1184.7016 2.74 26098 21249 2 1184.704402 593.3581 Pancreatic alpha-amylase OS=Homo sapiens OX=9606 GN=AMY2A PE=1 SV=2 4.37 3886.3 - 379633 - - - 2.3314 - 2.737 0.446 - 587.4 1 2 0 0.0028 11 0 0 0 8.81E+06 3.21E+06 - - - 5.0581 1 230117_WJC_METTL3_WT_vs_EV_F03.21250.21250.2 6.10E-05 13/26 R.YAIQLITAASLVC[160.03]R.K sp|Q9Y230|RUVB2_HUMAN 1 1577.8599 2.64 26099 21250 2 1577.8627 789.9373 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 8.22 3886.4 - 275220 - - - 1.7435 - 2.826 0.542 - 650.4 1 2 0 0.0028 14 0 0 0 3.34E+06 1.27E+06 - - - 5.6503 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21261.21261.2 0.00606 22-Oct R.NFGASLLLPGLK[136.11].Q "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN,tr|D6RJC7|D6RJC7_HUMAN" 4 1236.7322 1.53 26108 21261 2 1236.73501 619.3734 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 8.75 3887.7 - 1.29E+07 - - - 2.3053 - 1.984 0.492 - 283.9 1 2 0 0.0029 12 0 0 0 5.38E+07 3.52E+07 - - - 4.4767 1 230117_WJC_METTL3_WT_vs_EV_F03.21263.21263.2 0.00104 24-Dec K.NVLIVEDIIDTGK.T sp|P00492|HPRT_HUMAN 1 1427.7872 1.83 26110 21263 2 1427.789641 714.9009 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.03 3887.8 - 6.73E+06 - - - 1.737 - 2.485 0.504 - 388.2 1 2 0 0.0025 13 0 0 0 1.70E+07 9.30E+06 - - - 5.099 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.21266.21266.2 0.0747 14-Aug M.VLDLDLFR[166.11].V "sp|P49591|SYSC_HUMAN,tr|Q5T5C7|Q5T5C7_HUMAN" 2 999.5629 0.77 26113 21266 2 999.563724 500.7887 "Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3" 4.21 3887.9 - 4.04E+06 - - - 0.8724 - 1.738 0.285 - 260.8 1 2 0 0.0009 8 0 0 0 6.91E+06 8.92E+06 - - - 2.8128 1 230117_WJC_METTL3_WT_vs_EV_F03.21267.21267.2 9.13E-05 13/24 K.NVLIVEDIIDTGK[136.11].T sp|P00492|HPRT_HUMAN 1 1435.8014 1.83 26114 21267 2 1435.805328 718.908 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.03 3888 - 3.77E+06 - - - 2.7629 - 2.589 0.493 - 526.1 1 2 0 0.004 13 0 0 0 1.70E+07 9.30E+06 - - - 5.1225 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21268.21268.2 3.51E-06 24-Oct R.FGQDIISPLLSVK.E "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V414|A0A7I2V414_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|J3KNG4|J3KNG4_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|G3V5F3|G3V5F3_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|A0A7I2V4B9|A0A7I2V4B9_HUMAN,tr|H0YJY1|H0YJY1_HUMAN,tr|H0YJS6|H0YJS6_HUMAN,tr|G3V363|G3V363_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2V5R9|A0A7I2V5R9_HUMAN,tr|G3V4I1|G3V4I1_HUMAN,tr|A0A7I2V3Y3|A0A7I2V3Y3_HUMAN" 24 1415.8024 1.52 26115 21268 2 1415.803564 708.9085 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 5.84 3888.1 - 3.68E+06 - - - 0.8101 - 2.121 0.48 - 319.7 1 2 0 0.0011 13 0 0 0 1.52E+07 9.94E+06 - - - 4.5157 1 230117_WJC_METTL3_WT_vs_EV_F03.21270.21270.2 5.01E-06 22-Oct S.ILTIEDGIFEVK.S "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1375.7599 17.39 26117 21270 2 1375.764164 688.8872 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3888.2 - 2.08E+06 - - - 3.1117 - 2.174 0.48 - 327 1 1 0 0.0043 12 0 0 0 7.24E+06 4.17E+05 - - - 4.6282 0.9951 230117_WJC_METTL3_WT_vs_EV_F03.21271.21271.2 0.0659 22-Jun K.SLPVSVPVWGFK[136.11].E sp|Q96B36|AKTS1_HUMAN 1 1322.7478 2.75 26118 21271 2 1322.749416 662.3812 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 8.47 3888.2 - 2.00E+06 - - - 1.2149 - 1.18 0.205 - 74.9 1 2 0 0.0016 12 0 0 0 1.51E+07 5.49E+06 - - - 0.9901 1 230117_WJC_METTL3_WT_vs_EV_F03.21272.21272.2 3.35E-09 15/32 R.LWVGGLGPNTSLAALAR[166.11].E sp|Q8NDT2|RB15B_HUMAN 1 1704.9551 1.02 26119 21272 2 1704.956969 853.4848 Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3 9.75 3888.3 - 1.30E+06 - - - 1.1197 - 3.16 0.618 - 618.3 1 2 0 0.0019 17 0 0 0 3.58E+06 3.51E+06 - - - 6.4337 1 230117_WJC_METTL3_WT_vs_EV_F03.21273.21273.2 5.46E-08 Nov-32 R.LWVGGLGPNTSLAALAR.E sp|Q8NDT2|RB15B_HUMAN 1 1694.9468 1.02 26120 21273 2 1694.94991 848.4807 Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3 9.75 3888.4 - 1.28E+06 - - - 1.8408 - 2.657 0.557 - 192.3 1 2 0 0.0031 17 0 0 0 3.58E+06 3.51E+06 - - - 5.5565 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21274.21274.2 5.14E-05 26-Sep K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.75 26121 21274 2 1651.932245 826.9731 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3888.5 - 1.27E+06 - - - 0.362 - 2.013 0.439 - 233.3 1 2 0 0.0006 14 0 0 0 7.38E+07 9.81E+07 - - - 4.0389 1 230117_WJC_METTL3_WT_vs_EV_F03.21276.21276.2 0.000111 20-Sep K.VLAISDLVIYR.T "sp|Q9HBF4|ZFYV1_HUMAN,tr|G3V5N8|G3V5N8_HUMAN" 2 1260.7442 1.46 26123 21276 2 1260.750505 631.3794 Zinc finger FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZFYVE1 PE=1 SV=1 5.81 3888.7 - 1.23E+06 - - - 5.0216 - 2.178 0.489 - 300.6 1 2 0 0.0063 11 0 0 0 4.75E+06 3.26E+06 - - - 4.7565 1 230117_WJC_METTL3_WT_vs_EV_F03.21278.21278.2 6.68E-05 22-Nov K.TPLLLMLGQEDR.R "sp|P13798|ACPH_HUMAN,tr|C9JIF9|C9JIF9_HUMAN" 2 1384.7384 1.74 26125 21278 2 1384.730484 693.3765 Acylamino-acid-releasing enzyme OS=Homo sapiens OX=9606 GN=APEH PE=1 SV=4 4.37 3889 - 1.19E+06 - - - -5.7426 - 2.257 0.515 - 444 1 2 0 -0.008 12 0 0 0 2.71E+06 1.56E+06 - - - 4.9842 1 230117_WJC_METTL3_WT_vs_EV_F03.21279.21279.2 1.76E-07 14/30 R.IGNVEISQVTIVGIIR[166.11].H "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 1720.0122 0.85 26126 21279 2 1720.011781 861.0134 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 6 3889.1 - 1.09E+06 - - - -0.2669 - 2.915 0.574 - 569.9 1 2 0 -0.0005 16 0 0 0 2.04E+06 2.40E+06 - - - 5.9107 0.992 230117_WJC_METTL3_WT_vs_EV_F03.21282.21282.3 0.311 Oct-52 K.LFSLELVDESGEIR[166.11].A sp|P27694|RFA1_HUMAN 1 1615.8333 0.53 26128 21282 3 1615.835181 539.6184 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4 3889.4 - 37639.2 - - - 1.1808 - 1.907 0.126 - 130.1 1 2 0 0.0019 14 0 0 0 2.36E+06 4.47E+06 - - - 1.6598 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.21284.21284.2 7.43E-05 18-Sep K.DWVFLNYTYK[136.11].R "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN" 2 1355.6641 0.19 26130 21284 2 1355.668719 678.8393 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.83 3889.5 - 162236 - - - 3.3784 - 1.944 0.466 - 276 1 2 0 0.0046 10 0 0 0 7.33E+05 3.92E+06 - - - 4.337 0.9923 230117_WJC_METTL3_WT_vs_EV_F03.21285.21285.2 0.842 18-Jul R.FSQLVEELLK[136.11].L "sp|P38398|BRCA1_HUMAN,tr|E7ENB7|E7ENB7_HUMAN,tr|A0A494C182|A0A494C182_HUMAN,tr|Q3B891|Q3B891_HUMAN,tr|E7EUM2|E7EUM2_HUMAN,tr|Q5YLB2|Q5YLB2_HUMAN,tr|E7EWN5|E7EWN5_HUMAN,tr|A0A0U1RRA9|A0A0U1RRA9_HUMAN,tr|A0A2R8Y587|A0A2R8Y587_HUMAN,tr|E9PH68|E9PH68_HUMAN,tr|B7ZA85|B7ZA85_HUMAN,tr|E7EQW4|E7EQW4_HUMAN" 12 1212.6845 -1 26131 21285 2 1212.686792 607.3495 Breast cancer type 1 susceptibility protein OS=Homo sapiens OX=9606 GN=BRCA1 PE=1 SV=2 4.53 3889.7 - 320092 - - - 1.857 - 1.083 0.195 - 81.3 1 2 0 0.0023 10 0 0 0 0.00E+00 0.00E+00 - - - 0.7031 1 230117_WJC_METTL3_WT_vs_EV_F03.21288.21288.2 1.49E-10 17/26 K.LYTLVTYVPVTTFK.N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1643.9174 0.75 26132 21288 2 1643.920369 822.966 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3890.1 - 3.24E+06 - - - 1.7775 - 2.674 0.621 - 941.3 1 2 0 0.0029 14 0 0 0 7.38E+07 9.81E+07 - - - 6.095 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.21292.21292.2 0.122 16-Aug K.SLDIYSFIK[136.11].E "sp|Q9NR50|EI2BG_HUMAN,tr|H0Y580|H0Y580_HUMAN" 2 1092.5947 0.67 26136 21292 2 1092.596284 547.3046 Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens OX=9606 GN=EIF2B3 PE=1 SV=1 5.55 3890.5 - 1.80E+06 - - - 1.4845 - 1.711 0.159 - 163.9 1 2 0 0.0016 9 0 0 0 6.46E+06 9.71E+06 - - - 1.7687 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.21293.21293.3 0.066 16/52 K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.82 26137 21293 3 1651.93804 551.6512 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3890.7 - 1.53E+06 - - - 3.87 - 2.412 0.247 - 145.8 1 2 0 0.0064 14 0 0 0 1.64E+07 2.01E+07 - - - 3.6319 1 230117_WJC_METTL3_WT_vs_EV_F03.21294.21294.2 2.26E-06 13/24 R.TFLVDPNLDLSIR.E "sp|Q9BSJ2|GCP2_HUMAN,tr|A0A804HJH7|A0A804HJH7_HUMAN,tr|F2Z2B9|F2Z2B9_HUMAN,tr|A0A804HK74|A0A804HK74_HUMAN,tr|A0A804HL95|A0A804HL95_HUMAN,tr|A0A804HJ08|A0A804HJ08_HUMAN,tr|A0A804HJQ4|A0A804HJQ4_HUMAN,tr|A0A804HJS9|A0A804HJS9_HUMAN,tr|A0A804HI27|A0A804HI27_HUMAN" 9 1501.814 2.11 26138 21294 2 1501.817738 751.9143 Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2 4.21 3890.8 - 1.46E+06 - - - 2.4597 - 2.501 0.566 - 612.8 1 2 0 0.0037 13 0 0 0 5.74E+06 2.73E+06 - - - 5.573 1 230117_WJC_METTL3_WT_vs_EV_F03.21295.21295.2 7.17E-07 18-Nov R.VYNALVAFIR.A sp|Q9BW92|SYTM_HUMAN 1 1164.6655 0.73 26139 21295 2 1164.668687 583.34 "Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1" 8.72 3890.9 - 544818 - - - 2.7115 - 2.155 0.589 - 436.4 1 2 0 0.0032 10 0 0 0 2.89E+06 3.97E+06 - - - 5.5335 1 230117_WJC_METTL3_WT_vs_EV_F03.21312.21312.2 2.61E-06 22-Nov K.SLPVSVPVWGFK.E sp|Q96B36|AKTS1_HUMAN 1 1314.7336 2.75 26155 21312 2 1314.734637 658.3741 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 8.47 3893 - 370251 - - - 0.7819 - 1.974 0.545 - 357.4 1 2 0 0.001 12 0 0 0 1.51E+07 5.49E+06 - - - 4.8554 1 230117_WJC_METTL3_WT_vs_EV_F03.21323.21323.2 0.000148 15/20 R.EALDVLGAVLK.A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1126.6598 1.31 26164 21323 2 1126.663813 564.3372 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3894.3 - 2.42E+06 - - - 3.584 - 2.511 0.49 - 749.6 1 2 0 0.004 11 0 0 0 5.55E+07 4.22E+07 - - - 5.1495 1 230117_WJC_METTL3_WT_vs_EV_F03.21326.21326.3 1.69E-12 24/68 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.85 26167 21326 3 1936.018267 646.3445 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3894.7 - 1.23E+06 - - - 3.4494 - 3.447 0.658 - 646.2 1 2 0 0.0067 18 0 0 0 2.10E+07 2.46E+07 - - - 8.9557 1 230117_WJC_METTL3_WT_vs_EV_F03.21327.21327.2 1.14E-11 22/34 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.84 26168 21327 2 1936.015798 969.0131 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3894.8 - 1.02E+06 - - - 2.1741 - 4.458 0.646 - 1374.2 1 2 0 0.0042 18 0 0 0 2.17E+07 2.59E+07 - - - 7.4858 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.21328.21328.2 0.00131 24-Dec R.VLGATLLPDLIQK.V "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN,tr|H0YDG0|H0YDG0_HUMAN" 5 1379.8388 1.68 26169 21328 2 1379.842741 690.9267 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.81 3894.9 - 778982 - - - 2.8547 - 2.157 0.436 - 323.6 1 2 0 0.0039 13 0 0 0 7.85E+06 4.68E+06 - - - 4.233 1 230117_WJC_METTL3_WT_vs_EV_F03.21329.21329.2 1.51E-15 23/34 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.84 26170 21329 2 1926.008239 964.0089 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3895.1 - 758748 - - - 2.5545 - 4.465 0.71 - 1718.7 1 2 0 0.0049 18 0 0 0 2.17E+07 2.59E+07 - - - 7.9622 1 230117_WJC_METTL3_WT_vs_EV_F03.21333.21333.2 0.000104 24-Nov R.VLGATLLPDLIQK[136.11].V "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN,tr|H0YDG0|H0YDG0_HUMAN" 5 1387.853 1.68 26174 21333 2 1387.857156 694.9338 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.81 3895.6 - 573126 - - - 2.9931 - 2.359 0.47 - 287.9 1 2 0 0.0042 13 0 0 0 7.85E+06 4.68E+06 - - - 4.7138 1 230117_WJC_METTL3_WT_vs_EV_F03.21338.21338.2 0.000857 14/28 R.TIAIIAEGIPEALTR.K sp|P53396|ACLY_HUMAN 1 1566.8981 1.25 26179 21338 2 1566.902296 784.4563 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.53 3896.2 - 324210 - - - 2.6728 - 2.983 0.546 - 649.8 1 2 0 0.0042 15 0 0 0 1.24E+06 9.92E+05 - - - 5.7595 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.21339.21339.2 0.00894 28-Dec R.TIAIIAEGIPEALTR[166.11].K sp|P53396|ACLY_HUMAN 1 1576.9064 1.25 26180 21339 2 1576.910495 789.4605 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.53 3896.4 - 230012 - - - 2.6108 - 2.216 0.389 - 292.1 1 2 0 0.0041 15 0 0 0 1.24E+06 9.92E+05 - - - 3.8691 0.8756 230117_WJC_METTL3_WT_vs_EV_F03.21340.21340.2 21.2 16-Jun K.VGIVFTDGR[166.11].S "sp|P21941|MATN1_HUMAN,sp|O95460|MATN4_HUMAN,tr|A6NNA4|A6NNA4_HUMAN" 3 972.5268 0.89 26181 21340 2 972.528547 487.2707 Cartilage matrix protein OS=Homo sapiens OX=9606 GN=MATN1 PE=1 SV=1 5.81 3896.5 - 220614 - - - 1.7953 - 0.917 0.005 - 83 1 2 0 0.0017 9 0 0 0 7.45E+05 8.37E+05 - - - -1.1733 1 230117_WJC_METTL3_WT_vs_EV_F03.21345.21345.3 4.32E-10 20/68 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.85 26185 21345 3 1926.005819 643.0084 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3897.1 - 3.20E+06 - - - 1.298 - 3.221 0.533 - 395.7 1 2 0 0.0025 18 0 0 0 2.10E+07 2.46E+07 - - - 7.3944 1 230117_WJC_METTL3_WT_vs_EV_F03.21347.21347.3 8.59E-09 17/52 K.LPLFPEPLHVFAPR.A "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|K7ENW7|K7ENW7_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 7 1631.9188 0.52 26187 21347 3 1631.921714 544.9802 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 6.75 3897.2 - 923067 - - - 1.7954 - 3.393 0.476 - 535.1 1 2 0 0.0029 14 0 0 0 7.81E+06 1.51E+07 - - - 7.0929 1 230117_WJC_METTL3_WT_vs_EV_F03.21351.21351.2 3.72E-05 20-Nov K.TLC[160.03]PLC[160.03]FSILK[136.11].G "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1358.7182 1.25 26191 21351 2 1358.717797 680.3664 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 7.74 3897.6 - 419280 - - - -0.2716 - 2.114 0.539 - 318.9 1 2 0 -0.0004 11 0 0 0 3.76E+06 3.01E+06 - - - 5.047 0.9973 230117_WJC_METTL3_WT_vs_EV_F03.21353.21353.2 0.26 14-Jul K.QFLIDWVR.K "sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 2 1075.5815 0.47 26193 21353 2 1075.583579 538.798 ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2 5.84 3897.8 - 330272 - - - 1.9654 - 1.509 0.17 - 142 1 2 0 0.0021 8 0 0 0 1.77E+06 3.78E+06 - - - 1.5369 1 230117_WJC_METTL3_WT_vs_EV_F03.21358.21358.2 5.28E-08 24-Dec K.YVFLDPLAGAVTK[136.11].T "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|A8MWX3|WASH4_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 6 1400.7795 2.08 26198 21358 2 1400.774862 701.397 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 5.83 3898.5 - 189202 - - - -3.3132 - 2.499 0.633 - 384.8 1 2 0 -0.0046 13 0 0 0 1.13E+07 5.42E+06 - - - 6.0655 1 230117_WJC_METTL3_WT_vs_EV_F03.21363.21363.2 0.00129 14/20 K.IALLNVELELK.A sp|Q99832|TCPH_HUMAN 1 1253.7595 11.45 26201 21363 2 1253.760454 627.887 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.53 3899.2 - 5.37E+06 - - - 0.7697 - 2.713 0.429 - 716.2 1 2 0 0.001 11 0 0 0 6.70E+07 5.86E+06 - - - 4.9093 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.21364.21364.2 0.0301 18-Dec K.LLEPVLLLGK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1093.7111 1.63 26202 21364 2 1093.71242 547.8628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3899.2 - 5.43E+06 - - - 1.2224 - 2.144 0.295 - 425.3 1 2 0 0.0013 10 0 0 0 9.01E+08 5.52E+08 - - - 3.3483 0.999 230117_WJC_METTL3_WT_vs_EV_F03.21365.21365.2 0.00578 13/18 K.LLEPVLLLGK[136.11].E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1101.7253 1.63 26203 21365 2 1101.729416 551.8699 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3899.3 - 3.98E+06 - - - 3.7514 - 2.419 0.324 - 517.9 1 2 0 0.0041 10 0 0 0 8.98E+08 5.51E+08 - - - 3.8985 1 230117_WJC_METTL3_WT_vs_EV_F03.21366.21366.2 0.00111 13/22 R.LFQVEYAIEAIK.L sp|P28066|PSA5_HUMAN 1 1422.7759 2.1 26204 21366 2 1422.780368 712.3952 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 4.53 3899.4 - 3.53E+06 - - - 3.1628 - 2.559 0.456 - 556.5 1 2 0 0.0045 12 0 0 0 2.28E+07 1.09E+07 - - - 4.8799 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.21369.21369.3 4.14E-06 15/48 R.FFVTTLPAFFHAK[136.11].D sp|Q9H1E5|TMX4_HUMAN 1 1532.8271 1.29 26207 21369 3 1532.837099 511.9497 Thioredoxin-related transmembrane protein 4 OS=Homo sapiens OX=9606 GN=TMX4 PE=1 SV=1 8.76 3899.8 - 679254 - - - 6.5089 - 2.808 0.534 - 216 1 2 0 0.01 13 0 0 0 3.53E+06 2.72E+06 - - - 7.2901 1 230117_WJC_METTL3_WT_vs_EV_F03.21371.21371.2 1.75E-10 13/26 R.VIVSDVQESFIWVR[166.11].Y sp|Q15393|SF3B3_HUMAN 1 1685.9016 1.13 26209 21371 2 1685.906878 843.9581 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3900.1 - 358337 - - - 3.1147 - 2.778 0.582 - 422.1 1 2 0 0.0053 14 0 0 0 6.07E+06 5.36E+06 - - - 5.902 1 230117_WJC_METTL3_WT_vs_EV_F03.21373.21373.2 6.03E-07 13/20 R.FVASYLEYAFR.K sp|Q96GM8|TOE1_HUMAN 1 1364.6765 1.73 26211 21373 2 1364.680108 683.3455 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 6 3900.3 - 238464 - - - 2.6526 - 2.388 0.564 - 576.9 1 2 0 0.0036 11 0 0 0 1.80E+06 1.04E+06 - - - 5.5604 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.21375.21375.2 0.00185 18-Nov K.LLLNLVDC[160.03]IR.S "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1227.7009 3.74 26213 21375 2 1227.698726 614.8577 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 5.83 3900.6 - 233254 - - - -1.7944 - 2.344 0.42 - 466.6 1 2 0 -0.0022 10 0 0 0 1.64E+06 4.38E+05 - - - 4.5202 0.9869 230117_WJC_METTL3_WT_vs_EV_F03.21379.21379.2 0.149 14-Jun R.IPFAFWAR.Y "sp|Q96JG8|MAGD4_HUMAN,tr|A0A804HKI1|A0A804HKI1_HUMAN" 2 1006.5389 -1 26217 21379 2 1006.538228 504.2767 Melanoma-associated antigen D4 OS=Homo sapiens OX=9606 GN=MAGED4 PE=1 SV=3 9.75 3901.1 - 189701 - - - -0.6398 - 1.127 0.193 - 82.7 1 2 0 -0.0006 8 0 0 0 0.00E+00 0.00E+00 - - - 0.8269 1 230117_WJC_METTL3_WT_vs_EV_F03.21381.21381.2 2.48E-06 24-Oct K.FDFPVSYLPGPVK[136.11].A "sp|Q9NXE4|NSMA3_HUMAN,tr|A0A7P0T8J0|A0A7P0T8J0_HUMAN,tr|A0A7P0Z453|A0A7P0Z453_HUMAN,tr|C9J647|C9J647_HUMAN,tr|A0A7P0TAZ0|A0A7P0TAZ0_HUMAN,tr|A0A7P0T9J6|A0A7P0T9J6_HUMAN,tr|A0A7P0TB24|A0A7P0TB24_HUMAN" 7 1472.7795 2.49 26219 21381 2 1472.782394 737.397 Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3 5.83 3901.4 - 133448 - - - 1.963 - 1.814 0.557 - 199.1 1 2 0 0.0029 13 0 0 0 2.09E+06 8.39E+05 - - - 4.6826 1 230117_WJC_METTL3_WT_vs_EV_F03.21384.21384.2 0.00174 15/18 K.C[160.03]MQLTDFILK.F "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1267.6305 0.63 26221 21384 2 1267.635367 634.8225 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.83 3901.9 - 2.98E+06 - - - 3.8663 - 2.537 0.53 - 685.5 1 2 0 0.0049 10 0 0 0 1.33E+07 2.10E+07 - - - 5.5527 1 230117_WJC_METTL3_WT_vs_EV_F03.21386.21386.2 0.000181 16-Nov R.DIDAFWLQR.Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1162.5771 1.7 26223 21386 2 1162.58106 582.2958 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3902.1 - 1.48E+06 - - - 3.3993 - 2.104 0.507 - 427 1 2 0 0.004 9 0 0 0 2.61E+07 1.53E+07 - - - 4.9364 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.21387.21387.2 0.00365 20-Oct K.IALLNVELELK[136.11].A sp|Q99832|TCPH_HUMAN 1 1261.7737 11.45 26224 21387 2 1261.77759 631.8941 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.53 3902.3 - 1.30E+06 - - - 3.0917 - 2.456 0.191 - 397.2 1 2 0 0.0039 11 0 0 0 6.70E+07 5.86E+06 - - - 2.8812 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.21388.21388.2 0.00639 16-Nov R.DIDAFWLQR[166.11].Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1172.5854 1.74 26225 21388 2 1172.589302 587.3 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3902.4 - 1.22E+06 - - - 3.3465 - 2.045 0.372 - 429.8 1 2 0 0.0039 9 0 0 0 2.57E+07 1.48E+07 - - - 3.857 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.21389.21389.3 1.73E-06 13/52 R.VIVSDVQESFIWVR.Y sp|Q15393|SF3B3_HUMAN 1 1675.8934 1.14 26226 21389 3 1675.899101 559.6384 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3902.5 - 1.02E+06 - - - 3.4274 - 2.721 0.487 - 184.3 1 2 0 0.0057 14 0 0 0 2.91E+06 2.56E+06 - - - 6.6282 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.21391.21391.2 0.00681 14-Sep K.SFDLLILK[136.11].E "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 955.5834 1.05 26228 21391 2 955.586551 478.799 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 5.55 3902.8 - 577347 - - - 3.3299 - 1.618 0.297 - 233.6 1 2 0 0.0032 8 0 0 0 3.87E+06 3.68E+06 - - - 2.6849 1 230117_WJC_METTL3_WT_vs_EV_F03.21392.21392.2 0.000215 18-Nov K.QEVPIIIVFR.A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1212.723 1.33 26229 21392 2 1212.72833 607.3688 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3902.9 - 546406 - - - 4.3588 - 2.08 0.481 - 454.2 1 2 0 0.0053 10 0 0 0 2.44E+07 1.83E+07 - - - 4.6363 1 230117_WJC_METTL3_WT_vs_EV_F03.21393.21393.2 4.30E-07 20-Oct R.FVASYLEYAFR[166.11].K sp|Q96GM8|TOE1_HUMAN 1 1374.6848 -1 26230 21393 2 1374.687743 688.3497 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 6 3903.1 - 522848 - - - 2.1714 - 2.159 0.537 - 277.2 1 2 0 0.003 11 0 0 0 0.00E+00 0.00E+00 - - - 5.0884 1 230117_WJC_METTL3_WT_vs_EV_F03.21395.21395.2 0.00244 18-Nov K.QEVPIIIVFR[166.11].A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1222.7313 1.34 26232 21395 2 1222.737248 612.3729 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3903.3 - 486772 - - - 4.8531 - 2.082 0.5 - 436.7 1 2 0 0.0059 10 0 0 0 2.45E+07 1.83E+07 - - - 4.7791 0.9599 230117_WJC_METTL3_WT_vs_EV_F03.21398.21398.2 0.00366 14-Jul K.YLFDLPLK.V sp|Q5VUJ6|LRCH2_HUMAN 1 1007.5692 2.75 26235 21398 2 1007.576832 504.7919 Leucine-rich repeat and calponin homology domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LRCH2 PE=1 SV=2 5.83 3903.7 - 313733 - - - 7.6054 - 1.289 0.329 - 135 1 2 0 0.0077 8 0 0 0 1.20E+06 4.35E+05 - - - 2.2342 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.21401.21401.2 0.00669 Dec-36 R.LFVSDGVPGC[160.03]LPVLAAAGR.A "sp|P56192|SYMC_HUMAN,tr|F8W0S4|F8W0S4_HUMAN,tr|F8W0M7|F8W0M7_HUMAN,tr|F8VPL7|F8VPL7_HUMAN,tr|F5H2V6|F5H2V6_HUMAN,tr|F8VS26|F8VS26_HUMAN,tr|F8VZZ9|F8VZZ9_HUMAN" 7 1898.0084 2.35 26238 21401 2 1898.01024 950.0115 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 5.83 3904.1 - 201938 - - - 0.9673 - 2.228 0.148 - 182.3 1 2 0 0.0018 19 0 0 0 4.25E+06 1.81E+06 - - - 2.1031 1 230117_WJC_METTL3_WT_vs_EV_F03.21403.21403.2 2.41E-13 17/32 R.VLALSVETDYTFPLAEK[136.11].V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN" 5 1903.007 1.15 26240 21403 2 1903.010213 952.5108 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 4.14 3904.4 - 134383 - - - 1.6905 - 4.295 0.682 - 653.7 1 2 0 0.0032 17 0 0 0 9.31E+06 8.08E+06 - - - 7.6605 1 230117_WJC_METTL3_WT_vs_EV_F03.21405.21405.2 5.14E-06 18-Oct K.C[160.03]MQLTDFILK[136.11].F "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1275.6447 0.71 26241 21405 2 1275.648855 638.8296 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.83 3904.6 - 240469 - - - 3.2838 - 1.877 0.548 - 314 1 2 0 0.0042 10 0 0 0 1.32E+07 1.86E+07 - - - 4.8448 0.9098 230117_WJC_METTL3_WT_vs_EV_F03.21408.21408.2 0.207 14-Jul N.GVSQLIQR.E sp|P48201|AT5G3_HUMAN 1 899.5189 0.9 26244 21408 2 899.519917 450.7667 "ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1" 9.75 3904.8 - 800738 - - - 1.1695 - 1.652 0.218 - 212.8 1 1 0 0.0011 8 0 0 0 1.26E+08 1.40E+08 - - - 2.1648 1 230117_WJC_METTL3_WT_vs_EV_F03.21410.21410.2 3.42E-10 16/32 R.VLALSVETDYTFPLAEK.V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN" 5 1894.9928 1.15 26246 21410 2 1894.995925 948.5037 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 4.14 3904.9 - 626110 - - - 1.6512 - 3.457 0.638 - 700.5 1 2 0 0.0031 17 0 0 0 9.31E+06 8.08E+06 - - - 6.8019 0.9932 230117_WJC_METTL3_WT_vs_EV_F03.21411.21411.2 0.00634 18-Sep K.LFEISDIVIK.D sp|Q9NSD9|SYFB_HUMAN 1 1175.6802 1.85 26247 21411 2 1175.676025 588.8474 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 4.37 3905 - 460862 - - - -3.5307 - 1.833 0.333 - 252.5 1 2 0 -0.0042 10 0 0 0 1.29E+07 6.97E+06 - - - 3.1906 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21413.21413.2 0.00059 14-Aug K.NFAFLEFR[166.11].S "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1052.5319 1.3 26249 21413 2 1052.534447 527.2732 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3905.1 - 354690 - - - 2.4332 - 1.635 0.519 - 352.3 1 2 0 0.0026 8 0 0 0 2.37E+07 1.83E+07 - - - 4.3563 1 230117_WJC_METTL3_WT_vs_EV_F03.21414.21414.2 9.17E-07 24-Oct K.TVQTAVFLYSLYK.E "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 1531.8286 1.08 26250 21414 2 1531.830678 766.9216 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.17 3905.2 - 329470 - - - 1.3357 - 2.356 0.576 - 223.5 1 2 0 0.002 13 0 0 0 1.52E+07 1.41E+07 - - - 5.4941 1 230117_WJC_METTL3_WT_vs_EV_F03.21415.21415.2 6.52E-06 30-Nov K.TFVNITPAEVGVLVGK[136.11].D "sp|P07737|PROF1_HUMAN,tr|I3L3D5|I3L3D5_HUMAN" 2 1650.9436 0.56 26251 21415 2 1650.941755 826.4791 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 5.66 3905.2 - 272720 - - - -1.1224 - 2.117 0.528 - 261.3 1 2 0 -0.0019 16 0 0 0 1.49E+06 2.65E+06 - - - 4.7841 1 230117_WJC_METTL3_WT_vs_EV_F03.21422.21422.2 5.91E-05 13/22 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 541.05 26257 21422 2 1603.765725 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3906.1 - 1.46E+07 - - - 1.113 - 2.079 0.53 - 448.7 1 2 0 0.0018 12 0 0 0 3.70E+08 6.84E+05 - - - 4.8807 1 230117_WJC_METTL3_WT_vs_EV_F03.21426.21426.2 1.54E-08 15/24 K.VSASPLLYTLIEK.T "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1432.8177 2.12 26260 21426 2 1432.820827 717.4161 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 5.97 3906.4 - 2.04E+06 - - - 2.1594 - 3.127 0.588 - 1021.4 1 2 0 0.0031 13 0 0 0 2.04E+07 9.59E+06 - - - 6.309 1 230117_WJC_METTL3_WT_vs_EV_F03.21427.21427.2 4.30E-10 19/32 R.EIISEMGELGVLGPTIK[136.11].G "sp|Q92947|GCDH_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKT3|K7EKT3_HUMAN" 3 1792.9736 1.12 26261 21427 2 1792.975591 897.4941 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.25 3906.5 - 1.68E+06 - - - 1.1171 - 3.642 0.643 - 1277.2 1 2 0 0.002 17 0 0 0 3.81E+06 3.40E+06 - - - 6.9673 1 230117_WJC_METTL3_WT_vs_EV_F03.21428.21428.2 6.70E-06 13/24 K.VSASPLLYTLIEK[136.11].T "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1440.8319 2.12 26262 21428 2 1440.836449 721.4232 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 5.97 3906.6 - 1.28E+06 - - - 3.1343 - 2.677 0.524 - 602.3 1 2 0 0.0045 13 0 0 0 2.04E+07 9.59E+06 - - - 5.4371 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.21431.21431.2 0.0264 18-Sep K.LFEISDIVIK[136.11].D sp|Q9NSD9|SYFB_HUMAN 1 1183.6944 3.54 26265 21431 2 1183.696108 592.8545 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 4.37 3906.8 - 878857 - - - 1.4632 - 1.604 0.326 - 194.3 1 2 0 0.0017 10 0 0 0 1.22E+07 3.45E+06 - - - 2.7672 1 230117_WJC_METTL3_WT_vs_EV_F03.21432.21432.2 1.07E-09 Nov-32 R.TVLYPYC[160.03]APYALELDYR[166.11].Q "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 2116.0215 -1 26266 21432 2 2116.027615 1059.018 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 4.37 3906.9 - 528445 - - - 2.8969 - 2.354 0.654 - 293.8 1 2 0 0.0061 17 0 0 0 0.00E+00 0.00E+00 - - - 5.9743 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21433.21433.2 3.16E-05 28-Oct K.ILDVASLEVLNEVNR[166.11].R sp|Q92616|GCN1_HUMAN 1 1692.9286 -1 26267 21433 2 1692.932702 847.4716 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.14 3907.1 - 502018 - - - 2.4407 - 2.297 0.47 - 250.4 1 2 0 0.0041 15 0 0 0 0.00E+00 0.00E+00 - - - 4.5557 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21434.21434.2 0.0016 22-Oct R.EVAAGYLVPLLR[166.11].S sp|Q13395|TARB1_HUMAN 1 1309.7633 1.42 26268 21434 2 1309.765349 655.8889 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6.1 3907.1 - 422163 - - - 1.5316 - 2.094 0.43 - 300.7 1 2 0 0.002 12 0 0 0 2.40E+06 1.69E+06 - - - 4.161 1 230117_WJC_METTL3_WT_vs_EV_F03.21439.21439.2 1.49E-06 14/24 K.VFSATLGLVDIVK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1360.7966 1.15 26271 21439 2 1360.802351 681.4056 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3907.7 - 3.57E+06 - - - 4.224 - 2.643 0.623 - 610.6 1 2 0 0.0057 13 0 0 0 1.53E+08 1.34E+08 - - - 6.1351 1 230117_WJC_METTL3_WT_vs_EV_F03.21440.21440.2 1.87E-05 24-Nov K.VFSATLGLVDIVK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1368.8108 1.15 26272 21440 2 1368.812011 685.4127 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3907.7 - 3.66E+06 - - - 0.8825 - 2.341 0.52 - 301 1 2 0 0.0012 13 0 0 0 1.53E+08 1.34E+08 - - - 5.0644 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21444.21444.2 0.00188 16-Aug R.IPILFFANK.M "sp|Q9H0F7|ARL6_HUMAN,tr|A0A0J9YXT0|A0A0J9YXT0_HUMAN,tr|H7C5H6|H7C5H6_HUMAN" 3 1061.6274 2.56 26276 21444 2 1061.628126 531.821 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3908 - 2.05E+06 - - - 0.7281 - 1.813 0.45 - 190.1 1 2 0 0.0008 9 0 0 0 5.48E+06 2.14E+06 - - - 4.0858 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.21446.21446.3 0.000342 Oct-48 R.LLGNTFVALSDLR.C "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1417.7929 4.33 26278 21446 3 1417.79263 473.6049 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.84 3908.1 - 1.68E+06 - - - -0.201 - 1.793 0.325 - 145.9 1 2 0 -0.0003 13 0 0 0 6.25E+06 1.45E+06 - - - 3.7464 1 230117_WJC_METTL3_WT_vs_EV_F03.21447.21447.2 0.000116 13/22 K.IILDLISESPIK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1347.8105 1.14 26279 21447 2 1347.810197 674.9125 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3908.2 - 1.42E+06 - - - -0.2018 - 2.628 0.528 - 475.5 1 2 0 -0.0003 12 0 0 0 6.13E+08 5.40E+08 - - - 5.483 1 230117_WJC_METTL3_WT_vs_EV_F03.21449.21449.2 0.000427 13/22 K.IILDLISESPIK.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1339.7963 1.14 26281 21449 2 1339.806625 670.9054 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3908.3 - 1.16E+06 - - - 7.7295 - 2.479 0.509 - 542.5 1 2 0 0.0104 12 0 0 0 6.13E+08 5.40E+08 - - - 5.1859 1 230117_WJC_METTL3_WT_vs_EV_F03.21451.21451.2 6.78E-07 28-Dec K.IVFVPGC[160.03]SIPLTIVK[136.11].S sp|P54136|SYRC_HUMAN 1 1649.967 1.51 26283 21451 2 1649.966147 825.9908 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3908.5 - 1.13E+06 - - - -0.5091 - 2.246 0.54 - 253.6 1 2 0 -0.0008 15 0 0 0 3.92E+07 2.59E+07 - - - 5.0185 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.21454.21454.2 0.00037 13/24 K.LDNLLLDTEGFVK[136.11].L sp|Q16513|PKN2_HUMAN 1 1483.8014 1.81 26286 21454 2 1483.799231 742.908 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.03 3908.8 - 1.07E+06 - - - -1.4355 - 2.529 0.422 - 271.1 1 2 0 -0.0021 13 0 0 0 5.11E+06 2.83E+06 - - - 4.5385 1 230117_WJC_METTL3_WT_vs_EV_F03.21457.21457.2 3.05E-07 Sep-36 R.LVTLISQQATLLASNEAFK[136.11].K "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN,tr|C9JM14|C9JM14_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 7 2054.1503 -1 26289 21457 2 2054.154687 1028.0824 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 6 3909.2 - 0 - - - 2.1323 - 2.185 0.598 - 128.8 1 2 0 0.0044 19 0 0 0 0.00E+00 0.00E+00 - - - 5.3781 1 230117_WJC_METTL3_WT_vs_EV_F03.21463.21463.2 1.51E-05 28-Nov K.IVFVPGC[160.03]SIPLTIVK.S sp|P54136|SYRC_HUMAN 1 1641.9528 1.51 26294 21463 2 1641.955097 821.9837 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3909.9 - 1.70E+06 - - - 1.4069 - 2.131 0.556 - 228.8 1 2 0 0.0023 15 0 0 0 3.92E+07 2.59E+07 - - - 5.007 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.21464.21464.2 0.305 16-Oct R.LLPDFLLER[166.11].R "sp|Q12894|IFRD2_HUMAN,tr|H7C444|H7C444_HUMAN,tr|A0A0R4J2F6|A0A0R4J2F6_HUMAN" 3 1124.6469 0.38 26295 21464 2 1124.650049 563.3307 Interferon-related developmental regulator 2 OS=Homo sapiens OX=9606 GN=IFRD2 PE=1 SV=3 4.37 3910 - 1.18E+06 - - - 2.7858 - 1.986 0.216 - 193.1 1 2 0 0.0031 9 0 0 0 3.19E+06 8.34E+06 - - - 2.6204 1 230117_WJC_METTL3_WT_vs_EV_F03.21466.21466.2 6.62E-06 15/26 K.EIGLLADEIEIYGK.S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1561.8239 1.68 26297 21466 2 1561.834445 781.9192 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4 3910.3 - 846606 - - - 6.7261 - 2.648 0.481 - 594.4 1 2 0 0.0105 14 0 0 0 5.62E+06 3.34E+06 - - - 5.0341 1 230117_WJC_METTL3_WT_vs_EV_F03.21467.21467.2 0.000145 14/24 K.LDNLLLDTEGFVK.L sp|Q16513|PKN2_HUMAN 1 1475.7872 1.81 26298 21467 2 1475.791061 738.9009 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.03 3910.4 - 604975 - - - 2.6427 - 2.545 0.455 - 484.6 1 2 0 0.0039 13 0 0 0 5.11E+06 2.83E+06 - - - 4.7979 1 230117_WJC_METTL3_WT_vs_EV_F03.21470.21470.2 9.06E-07 14/26 K.EIGLLADEIEIYGK[136.11].S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1569.8381 1.66 26301 21470 2 1569.842418 785.9263 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4 3910.8 - 438263 - - - 2.7251 - 3.003 0.518 - 596.9 1 2 0 0.0043 14 0 0 0 5.54E+06 3.34E+06 - - - 5.625 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21482.21482.2 6.49E-05 16-Aug R.FWYFVSQLK[136.11].K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1224.6423 0.67 26311 21482 2 1224.643358 613.3284 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3912.3 - 2.88E+06 - - - 0.8794 - 1.641 0.477 - 200.5 1 2 0 0.0011 9 0 0 0 5.11E+07 7.68E+07 - - - 3.9967 1 230117_WJC_METTL3_WT_vs_EV_F03.21484.21484.2 0.000145 16-Sep R.FWYFVSQLK.K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1216.6281 0.67 26313 21484 2 1216.629256 609.3213 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3912.5 - 1.60E+06 - - - 0.9658 - 1.881 0.529 - 295.5 1 2 0 0.0012 9 0 0 0 5.11E+07 7.68E+07 - - - 4.7757 1 230117_WJC_METTL3_WT_vs_EV_F03.21486.21486.2 2.88E-05 16/24 R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 1.56 26315 21486 2 1448.792882 725.4024 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3912.7 - 1.25E+06 - - - 1.7918 - 3.366 0.529 - 1104.9 1 2 0 0.0026 13 0 0 0 2.40E+08 1.54E+08 - - - 6.0624 1 230117_WJC_METTL3_WT_vs_EV_F03.21487.21487.2 4.80E-11 17/26 K.FGGDFLVYPGDPLR.F "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN" 4 1551.7722 8.48 26316 21487 2 1551.772591 776.8934 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.21 3912.9 - 1.12E+06 - - - 0.2655 - 3.4 0.685 - 931 1 2 0 0.0004 14 0 0 0 1.56E+07 1.84E+06 - - - 7.1713 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.21488.21488.2 0.0101 26-Nov K.VLLLSSPGLEELYR.C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1587.8872 0.97 26317 21488 2 1587.886417 794.9509 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3913 - 1.11E+06 - - - -0.4988 - 2.122 0.356 - 290.3 1 2 0 -0.0008 14 0 0 0 3.07E+07 3.16E+07 - - - 3.5582 1 230117_WJC_METTL3_WT_vs_EV_F03.21491.21491.2 0.000843 16-Dec R.IDLAVLLGK.T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 940.5957 1.94 26320 21491 2 940.596495 471.3051 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3913.4 - 633570 - - - 0.8261 - 2.345 0.519 - 371.9 1 2 0 0.0008 9 0 0 0 4.12E+08 2.12E+08 - - - 5.3398 1 230117_WJC_METTL3_WT_vs_EV_F03.21494.21494.2 0.00028 26-Oct K.VLLVGADNFTLLGK[136.11].P "sp|Q7Z2W9|RM21_HUMAN,tr|H3BUY0|H3BUY0_HUMAN,tr|F5H7V8|F5H7V8_HUMAN" 3 1466.8588 1.19 26323 21494 2 1466.858468 734.4367 "39S ribosomal protein L21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL21 PE=1 SV=2" 5.81 3913.8 - 250008 - - - -0.2372 - 2.299 0.555 - 193.3 1 1 0 -0.0003 14 0 0 0 3.80E+06 3.20E+06 - - - 5.2292 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.21495.21495.2 2.29E-05 14-Sep R.FDMIFIVK.D "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1011.5463 2.07 26324 21495 2 1011.55206 506.7804 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 5.84 3913.9 - 243456 - - - 5.6695 - 1.791 0.508 - 194.6 1 2 0 0.0057 8 0 0 0 5.18E+06 2.51E+06 - - - 4.5489 1 230117_WJC_METTL3_WT_vs_EV_F03.21500.21500.2 0.00508 16-Dec R.IDLAVLLGK[136.11].T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 948.6099 1.94 26327 21500 2 948.609853 475.3122 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3914.5 - 5.65E+06 - - - -0.0685 - 2.382 0.484 - 385.3 1 2 0 -0.0001 9 0 0 0 4.12E+08 2.12E+08 - - - 5.1268 1 230117_WJC_METTL3_WT_vs_EV_F03.21505.21505.2 0.00079 20-Nov K.LPDVYGVFQFK.V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1311.6863 1.13 26332 21505 2 1311.68713 656.8504 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.83 3915 - 1.46E+06 - - - 0.6145 - 2.296 0.48 - 357.9 1 2 0 0.0008 11 0 0 0 2.56E+07 2.25E+07 - - - 4.8345 1 230117_WJC_METTL3_WT_vs_EV_F03.21507.21507.2 1.03E-05 13/20 K.LPDVYGVFQFK[136.11].V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1319.7005 1.13 26334 21507 2 1319.701663 660.8575 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.83 3915.3 - 1.18E+06 - - - 0.8631 - 2.351 0.545 - 619.4 1 2 0 0.0011 11 0 0 0 2.56E+07 2.25E+07 - - - 5.3786 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.21508.21508.3 3.07E-06 14/48 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.66 26335 21508 3 1438.782602 480.6013 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3915.4 - 1.03E+06 - - - 0.4073 - 2.716 0.48 - 335.6 1 2 0 0.0006 13 0 0 0 1.58E+07 9.54E+06 - - - 6.6004 0.9987 230117_WJC_METTL3_WT_vs_EV_F03.21509.21509.2 0.324 14-Jul K.ENLLDFIK[136.11].H "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 998.5528 2.3 26336 21509 2 998.552694 500.2837 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.37 3915.6 - 842274 - - - -0.1031 - 1.725 0.261 - 169.4 1 2 0 -0.0001 8 0 0 0 9.92E+07 4.32E+07 - - - 2.6131 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.21512.21512.3 0.0254 Oct-48 R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 1.66 26339 21512 3 1448.791425 483.9374 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3915.9 - 732492 - - - 0.7862 - 1.906 0.303 - 122.6 1 2 0 0.0011 13 0 0 0 1.58E+07 9.54E+06 - - - 3.6666 1 230117_WJC_METTL3_WT_vs_EV_F03.21513.21513.2 1.70E-07 13/26 R.SPSELFAQHIVTIV.H "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1539.8297 - 26340 21513 2 1539.828258 770.9221 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.22 3916 - 575666 - - - -0.9326 - 2.305 0.558 - 534.7 1 1 0 -0.0014 14 0 0 0 - - - - - 5.2575 0.9824 230117_WJC_METTL3_WT_vs_EV_F03.21519.21519.2 0.0242 16-Jul K.DLPPILLVR.G sp|P55011|S12A2_HUMAN 1 1034.6488 999 26346 21519 2 1034.654569 518.3317 Solute carrier family 12 member 2 OS=Homo sapiens OX=9606 GN=SLC12A2 PE=1 SV=1 5.84 3916.8 - 303690 - - - 5.5594 - 1.141 0.328 - 177.3 1 2 0 0.0058 9 0 0 0 4.24E+06 0.00E+00 - - - 1.8434 1 230117_WJC_METTL3_WT_vs_EV_F03.21521.21521.2 5.47E-08 26-Dec K.VLLLSSPGLEELYR[166.11].C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1597.8955 0.97 26347 21521 2 1597.894304 799.955 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3917 - 5.19E+06 - - - -0.7353 - 2.548 0.469 - 414.5 1 2 0 -0.0012 14 0 0 0 3.07E+07 3.16E+07 - - - 4.8518 0.9169 230117_WJC_METTL3_WT_vs_EV_F03.21523.21523.2 0.00561 24-Jul K.VALVTASTDGIGF.A "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN" 5 1249.6554 - 26349 21523 2 1249.655631 625.835 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 3.8 3917.2 - 1.31E+07 - - - 0.1704 - 1.395 0.362 - 148.4 1 1 0 0.0002 13 0 0 0 - - - - - 2.569 1 230117_WJC_METTL3_WT_vs_EV_F03.21525.21525.2 0.002 14-Oct K.LYDFYLFK.C sp|Q2TAL8|QRIC1_HUMAN 1 1107.5641 2.65 26351 21525 2 1107.565506 554.7893 Transcriptional regulator QRICH1 OS=Homo sapiens OX=9606 GN=QRICH1 PE=1 SV=1 5.83 3917.3 - 3.00E+06 - - - 1.2839 - 1.922 0.491 - 271.7 1 2 0 0.0014 8 0 0 0 7.70E+06 2.91E+06 - - - 4.6376 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.21526.21526.2 0.0759 22-Jul R.LNMGEIETLDDY.- "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1411.6177 - 26352 21526 2 1411.618557 706.8161 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 3.43 3917.4 - 2.99E+06 - - - 0.5986 - 1.288 0.305 - 139.2 1 2 0 0.0008 12 0 0 0 - - - - - 1.9594 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.21532.21532.2 0.268 16-Aug K.AIVLAAIFR.C "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 972.612 1.23 26358 21532 2 972.612208 487.3133 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 9.79 3917.9 - 1.05E+06 - - - 0.1758 - 1.755 0.136 - 144.1 1 2 0 0.0002 9 0 0 0 3.78E+06 3.07E+06 - - - 1.6727 0.9499 230117_WJC_METTL3_WT_vs_EV_F03.21538.21538.2 0.595 22-Jun K.TLVLLLGVDPSR[166.11].Q sp|P42345|MTOR_HUMAN 1 1291.7739 -1 26364 21538 2 1291.776529 646.8942 Serine\threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 5.5 3918.5 - 702318 - - - 2.0298 - 0.888 0.13 - 42 3 2 0 0.0026 12 0 0 0 0.00E+00 0.00E+00 - - - -0.5253 1 230117_WJC_METTL3_WT_vs_EV_F03.21542.21542.2 0.0184 16/24 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.56 26367 21542 2 1438.78219 720.3983 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3919 - 7.98E+06 - - - 0.1209 - 3.263 0.468 - 1071.4 1 2 0 0.0002 13 0 0 0 2.40E+08 1.54E+08 - - - 5.5329 1 230117_WJC_METTL3_WT_vs_EV_F03.21543.21543.2 4.00E-07 22-Nov R.YFPTQALNFAFK[136.11].D "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 1453.7485 1.16 26368 21543 2 1453.748226 727.8815 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.59 3919.1 - 3.74E+06 - - - -0.2139 - 2.331 0.562 - 406.8 1 2 0 -0.0003 12 0 0 0 1.78E+08 1.54E+08 - - - 5.4186 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21544.21544.2 0.00274 14-Aug R.ILEFFGLK.K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 965.5586 1.81 26369 21544 2 965.559977 483.7866 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3919.1 - 2.68E+06 - - - 1.4209 - 1.585 0.454 - 159.8 1 2 0 0.0014 8 0 0 0 1.05E+08 5.81E+07 - - - 3.7829 0.9982 230117_WJC_METTL3_WT_vs_EV_F03.21550.21550.2 0.0118 14-Aug R.ILEFFGLK[136.11].K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 973.5728 1.81 26373 21550 2 973.572012 487.7937 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3919.8 - 3.48E+06 - - - -0.8145 - 1.654 0.291 - 151.7 1 2 0 -0.0008 8 0 0 0 1.05E+08 5.81E+07 - - - 2.7077 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.21551.21551.2 6.75E-05 22-Nov R.LLFPAVDDNLLK[136.11].F "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1364.7795 1.77 26374 21551 2 1364.776984 683.397 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 4.21 3919.9 - 1.61E+06 - - - -1.8457 - 2.148 0.464 - 361.2 1 2 0 -0.0025 12 0 0 0 2.14E+07 1.20E+07 - - - 4.4789 0.9862 230117_WJC_METTL3_WT_vs_EV_F03.21552.21552.2 0.00935 16-Sep K.EVNLVLLLK.N "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1039.6641 203.29 26375 21552 2 1039.67136 520.8393 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 6.1 3920 - 1.59E+06 - - - 6.9522 - 1.849 0.307 - 369.6 1 2 0 0.0072 9 0 0 0 1.08E+07 5.30E+04 - - - 3.0844 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.21557.21557.2 0.0985 16-Sep R.DDLLGFALR.E sp|Q9Y617|SERC_HUMAN 1 1018.5447 2.2 26380 21557 2 1018.546249 510.2796 Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1 PE=1 SV=2 4.21 3920.7 - 664983 - - - 1.4766 - 1.76 0.253 - 227.7 1 2 0 0.0015 9 0 0 0 1.56E+07 7.07E+06 - - - 2.5447 0.9843 230117_WJC_METTL3_WT_vs_EV_F03.21565.21565.2 0.000576 16-Aug K.FLQLC[160.03]IFPR.C "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN,tr|H0Y815|H0Y815_HUMAN" 3 1192.6427 1.69 26388 21565 2 1192.638214 597.3286 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 8.25 3921.7 - 318070 - - - -3.7497 - 1.682 0.245 - 184.8 1 2 0 -0.0045 9 0 0 0 3.72E+06 2.20E+06 - - - 2.3535 1 230117_WJC_METTL3_WT_vs_EV_F03.21571.21571.2 6.95E-06 26-Sep R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.11 26392 21571 2 1470.882269 736.4478 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3922.5 - 1.61E+07 - - - 0.8621 - 1.886 0.599 - 196 1 2 0 0.0013 14 0 0 0 2.24E+08 2.03E+08 - - - 5.057 1 230117_WJC_METTL3_WT_vs_EV_F03.21572.21572.2 9.03E-07 17/26 R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.11 26393 21572 2 1478.895831 740.4549 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3922.6 - 1.46E+07 - - - 0.426 - 2.853 0.609 - 702.4 1 2 0 0.0006 14 0 0 0 2.24E+08 2.03E+08 - - - 6.1697 1 230117_WJC_METTL3_WT_vs_EV_F03.21575.21575.2 3.18E-06 13/22 K.WLAPDGLIFPDR[166.11].A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1408.7379 0.76 26396 21575 2 1408.740589 705.3762 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3922.7 - 3.28E+06 - - - 1.94 - 2.736 0.522 - 595.7 1 2 0 0.0027 12 0 0 0 6.38E+07 8.35E+07 - - - 5.5439 1 230117_WJC_METTL3_WT_vs_EV_F03.21577.21577.3 2.89E-08 22/52 R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.21 26398 21577 3 1478.896744 493.9723 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3922.9 - 2.33E+06 - - - 1.0433 - 3.131 0.553 - 610.2 1 2 0 0.0015 14 0 0 0 2.90E+07 2.39E+07 - - - 7.7382 1 230117_WJC_METTL3_WT_vs_EV_F03.21578.21578.3 6.23E-07 19/52 R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.21 26399 21578 3 1470.883055 491.3009 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3923 - 2.16E+06 - - - 1.3964 - 2.829 0.581 - 408.4 1 2 0 0.0021 14 0 0 0 2.90E+07 2.39E+07 - - - 7.7806 1 230117_WJC_METTL3_WT_vs_EV_F03.21580.21580.2 0.00069 18-Nov R.IQFFAIEIAR.N sp|Q9BVG4|PBDC1_HUMAN 1 1206.6761 4.19 26401 21580 2 1206.678315 604.3453 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 6 3923.1 - 1.86E+06 - - - 1.8406 - 2.288 0.444 - 425.4 1 2 0 0.0022 10 0 0 0 1.52E+07 3.64E+06 - - - 4.63 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21581.21581.2 3.00E-05 22-Dec R.FSPIPFPPLSYK.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1391.7489 8.75 26402 21581 2 1391.751455 696.8817 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3923.2 - 1.36E+06 - - - 1.8179 - 1.976 0.449 - 289.7 1 2 0 0.0025 12 0 0 0 1.38E+07 1.57E+06 - - - 4.1485 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21582.21582.2 0.000555 20-Oct K.AFVDFLSDEIK.E sp|Q07021|C1QBP_HUMAN 1 1282.6445 2.08 26403 21582 2 1282.646018 642.3295 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.03 3923.3 - 1.11E+06 - - - 1.1687 - 2.007 0.493 - 283.7 1 2 0 0.0015 11 0 0 0 2.48E+07 1.19E+07 - - - 4.5664 1 230117_WJC_METTL3_WT_vs_EV_F03.21583.21583.2 4.59E-05 20/28 R.ELALALQEALEPAVR.L sp|Q5RKV6|EXOS6_HUMAN 1 1621.9039 1 26404 21583 2 1621.907634 811.9592 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 4.25 3923.4 - 784051 - - - 2.2887 - 3.543 0.466 - 1603 1 2 0 0.0037 15 0 0 0 8.78E+06 8.76E+06 - - - 5.5917 1 230117_WJC_METTL3_WT_vs_EV_F03.21585.21585.2 0.000152 17/26 K.TALALAIAQELGSK.V "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1384.7926 -1 26406 21585 2 1384.795052 693.4036 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 5.66 3923.7 - 651764 - - - 1.7851 - 3.193 0.535 - 1224.9 1 2 0 0.0025 14 0 0 0 0.00E+00 0.00E+00 - - - 5.9051 1 230117_WJC_METTL3_WT_vs_EV_F03.21586.21586.2 1.91E-08 19/30 K.LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1793.9075 0.81 26407 21586 2 1793.910887 897.961 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3923.8 - 618859 - - - 1.8881 - 3.243 0.589 - 1095.3 1 2 0 0.0034 16 0 0 0 1.57E+07 1.94E+07 - - - 6.2828 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21589.21589.2 0.00021 13/26 K.IPVDTYNNILTVLK.L sp|Q96QK1|VPS35_HUMAN 1 1601.9029 2.19 26410 21589 2 1601.903862 801.9587 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 5.83 3924.1 - 577751 - - - 0.6261 - 1.97 0.45 - 291.3 1 2 0 0.001 14 0 0 0 6.67E+06 3.04E+06 - - - 4.0659 0.999 230117_WJC_METTL3_WT_vs_EV_F03.21593.21593.2 2.2 24-Dec R.LGPLLLDPSLAVR[166.11].E sp|Q7Z4Q2|HEAT3_HUMAN 1 1372.8318 1.24 26413 21593 2 1372.831855 687.4232 HEAT repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=HEATR3 PE=1 SV=2 5.84 3924.6 - 752652 - - - 0.0714 - 2.178 0.235 - 428.1 1 2 0 0.0001 13 0 0 0 7.86E+06 6.33E+06 - - - 2.7745 1 230117_WJC_METTL3_WT_vs_EV_F03.21595.21595.2 3.35E-06 20/30 K.LFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1783.8992 0.81 26415 21595 2 1783.899229 892.9569 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3924.8 - 6.75E+06 - - - -0.0006 - 3.386 0.611 - 1283.3 1 2 0 0 16 0 0 0 1.57E+07 1.94E+07 - - - 6.5524 1 230117_WJC_METTL3_WT_vs_EV_F03.21596.21596.2 0.000608 14/20 Q.AFADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1170.7012 9.22 26416 21596 2 1170.703679 586.3579 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3924.9 - 4.50E+06 - - - 2.0782 - 2.383 0.505 - 516 1 1 0 0.0024 11 0 0 0 7.34E+06 7.96E+05 - - - 5.1193 0.9955 230117_WJC_METTL3_WT_vs_EV_F03.21597.21597.2 0.00268 14-Jul R.SWLLPVIR[166.11].D sp|Q5JTH9|RRP12_HUMAN 1 992.6047 -1 26417 21597 2 992.605778 497.3096 RRP12-like protein OS=Homo sapiens OX=9606 GN=RRP12 PE=1 SV=2 9.47 3924.9 - 3.58E+06 - - - 1.1294 - 1.455 0.121 - 271.6 1 2 0 0.0011 8 0 0 0 0.00E+00 0.00E+00 - - - 1.0654 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21599.21599.2 0.00354 18-Oct R.SLGPVELLLR.G "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1095.6652 2.47 26419 21599 2 1095.66765 548.8399 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.72 3925.1 - 2.76E+06 - - - 2.2406 - 1.948 0.467 - 358.9 1 2 0 0.0025 10 0 0 0 1.73E+07 7.00E+06 - - - 4.3507 1 230117_WJC_METTL3_WT_vs_EV_F03.21600.21600.2 2.15E-06 13/26 K.TYVLNPLAPEFIPR.A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1628.8926 2 26420 21600 2 1628.89283 815.4536 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.66 3925.2 - 2.74E+06 - - - 0.1234 - 2.765 0.583 - 504.2 1 2 0 0.0002 14 0 0 0 7.24E+06 3.63E+06 - - - 5.8992 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21605.21605.2 0.000844 13/18 R.VVTDLISLIR.Q sp|P38432|COIL_HUMAN 1 1127.6914 -1 26425 21605 2 1127.693435 564.853 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3925.8 - 1.77E+06 - - - 1.7957 - 2.441 0.413 - 620 1 2 0 0.002 10 0 0 0 0.00E+00 0.00E+00 - - - 4.5818 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.21608.21608.2 0.00686 16-Jul R.GYPTLLLFR.G sp|Q8NBS9|TXND5_HUMAN 1 1078.6175 1.27 26428 21608 2 1078.616383 540.316 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 8.75 3926.2 - 1.32E+06 - - - -1.0504 - 1.559 0.342 - 212.4 1 2 0 -0.0011 9 0 0 0 1.19E+07 9.38E+06 - - - 2.8513 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21610.21610.2 0.00196 18-Oct R.SLGPVELLLR[166.11].G "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1105.6735 2.47 26430 21610 2 1105.675792 553.844 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.72 3926.5 - 1.13E+06 - - - 2.1046 - 1.929 0.439 - 290.2 1 2 0 0.0023 10 0 0 0 1.73E+07 7.00E+06 - - - 4.1166 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21611.21611.3 0.0021 Dec-60 K.LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1793.9075 -1 26431 21611 3 1793.910273 598.9764 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3926.6 - 1.08E+06 - - - 1.5458 - 2.087 0.332 - 149.6 1 2 0 0.0028 16 0 0 0 0.00E+00 0.00E+00 - - - 4.1285 1 230117_WJC_METTL3_WT_vs_EV_F03.21613.21613.2 0.000459 20-Oct K.LDTSQWPLLLK[136.11].N "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1320.7533 0.79 26432 21613 2 1320.756253 661.3839 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 5.84 3926.9 - 735509 - - - 2.2449 - 2.324 0.479 - 408.5 1 2 0 0.003 11 0 0 0 7.31E+06 9.31E+06 - - - 4.8593 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.21618.21618.2 0.0451 18-Oct R.VVTDLISLIR[166.11].Q sp|P38432|COIL_HUMAN 1 1137.6997 -1 26437 21618 2 1137.700799 569.8571 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3927.2 - 1.51E+06 - - - 0.9836 - 2.016 0.258 - 355.8 1 2 0 0.0011 10 0 0 0 0.00E+00 0.00E+00 - - - 2.9033 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21619.21619.2 0.006 20-Oct R.LFEFAGYDVLR[166.11].L sp|P54136|SYRC_HUMAN 1 1338.6848 -1 26438 21619 2 1338.685656 670.3497 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3927.3 - 1.45E+06 - - - 0.6708 - 2.038 0.428 - 310.1 1 2 0 0.0009 11 0 0 0 0.00E+00 0.00E+00 - - - 4.128 0.994 230117_WJC_METTL3_WT_vs_EV_F03.21620.21620.2 0.316 16-Jul R.FYELLVTGR.Y "sp|Q9UPS6|SET1B_HUMAN,tr|A0A0A0MQV9|A0A0A0MQV9_HUMAN" 2 1096.5917 2.12 26439 21620 2 1096.593952 549.3031 Histone-lysine N-methyltransferase SETD1B OS=Homo sapiens OX=9606 GN=SETD1B PE=1 SV=3 6 3927.3 - 1.45E+06 - - - 2.0573 - 1.295 0.155 - 201.8 1 2 0 0.0023 9 0 0 0 7.83E+06 3.69E+06 - - - 0.933 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.21622.21622.2 0.0379 18-Oct R.DAVLLLFANK.Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1102.6386 2.29 26441 21622 2 1102.641457 552.3266 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3927.4 - 918336 - - - 2.5493 - 2.106 0.351 - 445.7 1 2 0 0.0028 10 0 0 0 2.01E+07 8.80E+06 - - - 3.7115 0.9636 230117_WJC_METTL3_WT_vs_EV_F03.21623.21623.2 0.0318 16-Sep N.VLIIGELLK.Q "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 996.6583 10.45 26442 21623 2 996.659155 499.3364 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.97 3927.6 - 816872 - - - 0.8388 - 1.733 0.372 - 245.8 1 1 0 0.0008 9 0 0 0 6.41E+06 6.14E+05 - - - 3.3791 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21626.21626.2 0.000833 20-Oct K.LDTSQWPLLLK.N "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1312.7391 0.71 26445 21626 2 1312.741947 657.3768 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 5.84 3927.8 - 656160 - - - 2.1779 - 2.266 0.422 - 432.6 1 2 0 0.0029 11 0 0 0 8.81E+06 1.25E+07 - - - 4.3699 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.21634.21634.2 0.00207 16-Jul R.GYPTLLLFR[166.11].G sp|Q8NBS9|TXND5_HUMAN 1 1088.6258 1.64 26452 21634 2 1088.627812 545.3202 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 8.75 3928.7 - 1.48E+06 - - - 1.8611 - 1.552 0.326 - 174.7 1 2 0 0.002 9 0 0 0 9.46E+06 5.77E+06 - - - 2.7198 1 230117_WJC_METTL3_WT_vs_EV_F03.21636.21636.2 5.64E-05 20-Nov R.LFEFAGYDVLR.L sp|P54136|SYRC_HUMAN 1 1328.6765 1.47 26454 21636 2 1328.68156 665.3455 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3928.9 - 1.28E+07 - - - 3.8173 - 2.355 0.553 - 472.1 1 2 0 0.0051 11 0 0 0 2.11E+07 1.43E+07 - - - 5.441 1 230117_WJC_METTL3_WT_vs_EV_F03.21637.21637.2 0.0225 18-Nov R.DAVLLLFANK[136.11].Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1110.6528 2.29 26455 21637 2 1110.656754 556.3337 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3928.9 - 4.56E+06 - - - 3.5187 - 2.423 0.465 - 542.7 1 2 0 0.0039 10 0 0 0 2.02E+07 8.85E+06 - - - 4.9446 1 230117_WJC_METTL3_WT_vs_EV_F03.21638.21638.2 4.16E-10 14/30 R.IIGATDSSGELMFLMK.W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1711.8525 1.21 26456 21638 2 1711.856855 856.9335 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3929 - 4.18E+06 - - - 2.5557 - 3.339 0.648 - 411 1 2 0 0.0044 16 0 0 0 1.18E+07 9.76E+06 - - - 6.79 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.21641.21641.2 2.29E-05 20-Dec K.VTDLLGGLFSK[136.11].T "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1156.6583 2.33 26459 21641 2 1156.663176 579.3364 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.81 3929.3 - 3.17E+06 - - - 4.194 - 2.624 0.356 - 685.2 1 2 0 0.0049 11 0 0 0 5.33E+07 2.28E+07 - - - 4.2786 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.21642.21642.2 0.00018 16-Aug K.APWELLELR[166.11].V "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A6Q8PF15|A0A6Q8PF15_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN,tr|A0A6Q8PFC1|A0A6Q8PFC1_HUMAN" 6 1135.6265 0.98 26460 21642 2 1135.630672 568.8205 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.53 3929.3 - 2.92E+06 - - - 3.6605 - 1.8 0.437 - 413.4 1 2 0 0.0042 9 0 0 0 6.19E+06 6.29E+06 - - - 3.9679 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.21647.21647.2 0.0884 18-Jul K.FLDVLELAEK.F "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1175.6438 -1 26465 21647 2 1175.647059 588.8292 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.14 3930 - 1.55E+06 - - - 2.7798 - 1.514 0.205 - 94.1 1 2 0 0.0033 10 0 0 0 0.00E+00 0.00E+00 - - - 1.7118 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21659.21659.2 0.000104 20-Aug R.SVVTVIDVFYK.Y sp|Q5D862|FILA2_HUMAN 1 1268.7016 22.37 26476 21659 2 1268.703124 635.3581 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 5.55 3931.3 - 1.89E+06 - - - 1.1697 - 2.007 0.456 - 186.3 1 2 0 0.0015 11 0 0 0 5.28E+07 2.36E+06 - - - 4.2931 0.9614 230117_WJC_METTL3_WT_vs_EV_F03.21663.21663.3 0.705 May-60 R.IIGATDSSGELMFLMK.W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1711.8525 1.28 26480 21663 3 1711.853879 571.6248 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3931.4 - 312902 - - - 0.8172 - 1.22 0.156 - 28.1 2 2 0 0.0014 16 0 0 0 1.78E+06 1.40E+06 - - - 0.6498 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21679.21679.2 0.000312 20-Sep K.YPSPFFVFGEK[136.11].L sp|Q08211|DHX9_HUMAN 1 1324.6583 1 26495 21679 2 1324.659766 663.3364 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3933 - 1.06E+06 - - - 1.0878 - 2.03 0.463 - 271.1 1 2 0 0.0014 11 0 0 0 6.10E+07 6.12E+07 - - - 4.3757 1 230117_WJC_METTL3_WT_vs_EV_F03.21680.21680.2 7.11E-08 20-Nov K.YPSPFFVFGEK.L sp|Q08211|DHX9_HUMAN 1 1316.6441 0.99 26496 21680 2 1316.646521 659.3293 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3933.1 - 785093 - - - 1.8198 - 2.137 0.531 - 445.3 1 2 0 0.0024 11 0 0 0 6.04E+07 6.12E+07 - - - 5.0166 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.21682.21682.2 0.00179 14-Sep R.AAFLNFFR.D sp|Q5JTZ9|SYAM_HUMAN 1 984.5181 2.67 26498 21682 2 984.518207 493.2663 "Alanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=AARS2 PE=1 SV=1" 9.79 3933.3 - 343169 - - - 0.0711 - 1.581 0.424 - 291.3 1 2 0 0.0001 8 0 0 0 3.23E+06 1.21E+06 - - - 3.5541 1 230117_WJC_METTL3_WT_vs_EV_F03.21685.21685.2 2.03E-07 22-Sep R.FSTFFDDAPVFR[166.11].L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1457.6855 -1 26501 21685 2 1457.689646 729.85 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3933.4 - 176090 - - - 2.8538 - 1.989 0.589 - 225.3 1 2 0 0.0042 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1993 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.21687.21687.2 0.00729 14-Jul R.AAFLNFFR[166.11].D sp|Q5JTZ9|SYAM_HUMAN 1 994.5264 2.67 26503 21687 2 994.529149 498.2705 "Alanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=AARS2 PE=1 SV=1" 9.79 3933.6 - 131389 - - - 2.7571 - 1.693 0.344 - 169.6 1 2 0 0.0027 8 0 0 0 3.23E+06 1.21E+06 - - - 3.1688 1 230117_WJC_METTL3_WT_vs_EV_F03.21690.21690.2 3.26E-10 17/30 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 0.95 26504 21690 2 1807.928306 904.9689 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3934 - 4.37E+06 - - - 2.8519 - 3.364 0.608 - 829.8 1 2 0 0.0052 16 0 0 0 4.72E+07 4.98E+07 - - - 6.5126 1 230117_WJC_METTL3_WT_vs_EV_F03.21692.21692.2 5.00E-06 16/30 K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 -1 26506 21692 2 1797.920223 899.9647 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3934.2 - 3.83E+06 - - - 2.9718 - 3.227 0.621 - 602 1 2 0 0.0053 16 0 0 0 0.00E+00 0.00E+00 - - - 6.5063 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.21695.21695.2 0.000101 18-Nov K.AWLLSMIQSK[136.11].C "sp|Q9UBU9|NXF1_HUMAN,tr|E9PLA7|E9PLA7_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1183.6515 0.9 26509 21695 2 1183.654717 592.833 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 8.8 3934.5 - 1.50E+06 - - - 2.7466 - 2.177 0.409 - 410.4 1 2 0 0.0033 10 0 0 0 3.60E+06 4.02E+06 - - - 4.2323 0.999 230117_WJC_METTL3_WT_vs_EV_F03.21696.21696.2 0.00104 20-Sep R.VINQMLEFAFR.Y "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 1366.7067 1.99 26510 21696 2 1366.711961 684.3606 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 5.97 3934.7 - 1.17E+06 - - - 3.8187 - 1.987 0.419 - 258.3 1 2 0 0.0052 11 0 0 0 4.46E+06 2.25E+06 - - - 3.9916 1 230117_WJC_METTL3_WT_vs_EV_F03.21698.21698.2 1.00E-08 13/22 R.FSTFFDDAPVFR.L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1447.6772 -1 26512 21698 2 1447.681378 724.8459 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3934.9 - 1.14E+06 - - - 2.875 - 2.348 0.627 - 543.5 1 2 0 0.0042 12 0 0 0 0.00E+00 0.00E+00 - - - 5.9166 0.9658 230117_WJC_METTL3_WT_vs_EV_F03.21709.21709.2 0.0543 22-Oct R.FGPIPLGSLGWK[136.11].T "sp|Q16795|NDUA9_HUMAN,tr|A0A3B3ISG8|A0A3B3ISG8_HUMAN" 2 1278.7216 5.42 26523 21709 2 1278.730155 640.3681 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA9 PE=1 SV=2" 8.75 3936.3 - 555084 - - - 6.695 - 1.558 0.23 - 216.2 1 2 0 0.0086 12 0 0 0 1.49E+07 2.76E+06 - - - 1.9038 0.9721 230117_WJC_METTL3_WT_vs_EV_F03.21712.21712.3 0.178 Sep-56 K.GLAPDLPEDLYHLIK.K "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1692.9087 1.38 26525 21712 3 1692.916443 565.3102 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 4.54 3936.7 - 716693 - - - 4.5897 - 1.707 0.174 - 80.2 1 2 0 0.0078 15 0 0 0 2.91E+06 2.10E+06 - - - 1.8731 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.21713.21713.2 0.00106 14-Jul R.GFGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 921.5204 1.09 26526 21713 2 921.523877 461.7675 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3936.7 - 2.84E+07 - - - 3.8002 - 1.538 0.439 - 147.6 1 2 0 0.0035 8 0 0 0 2.45E+08 2.24E+08 - - - 3.5807 0.9979 230117_WJC_METTL3_WT_vs_EV_F03.21714.21714.2 0.00157 14-Aug R.GFGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 913.5062 1.09 26527 21714 2 913.510384 457.7604 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3936.8 - 2.34E+07 - - - 4.6075 - 1.489 0.459 - 207.6 1 2 0 0.0042 8 0 0 0 2.45E+08 2.24E+08 - - - 3.6305 0.998 230117_WJC_METTL3_WT_vs_EV_F03.21715.21715.2 0.00309 20-Sep R.IFGLLMGTLQK[136.11].F sp|Q9H307|PININ_HUMAN 1 1227.7141 1.16 26528 21715 2 1227.719762 614.8643 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3936.8 - 7.78E+06 - - - 4.6395 - 1.958 0.385 - 197.9 1 2 0 0.0057 11 0 0 0 3.30E+07 2.85E+07 - - - 3.7005 1 230117_WJC_METTL3_WT_vs_EV_F03.21716.21716.2 0.000669 20-Dec R.IFGLLMGTLQK.F sp|Q9H307|PININ_HUMAN 1 1219.6999 1.16 26529 21716 2 1219.705655 610.8572 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3936.9 - 7.03E+06 - - - 4.7462 - 2.312 0.514 - 426.4 1 2 0 0.0058 11 0 0 0 3.30E+07 2.85E+07 - - - 5.1029 1 230117_WJC_METTL3_WT_vs_EV_F03.21717.21717.2 0.0177 15/24 N.IVGLVGVDQFLVK.T sp|P13639|EF2_HUMAN 1 1385.8282 -1 26530 21717 2 1385.833864 693.9214 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3936.9 - 5.14E+06 - - - 4.0597 - 2.696 0.53 - 580.3 1 1 0 0.0056 13 0 0 0 0.00E+00 0.00E+00 - - - 5.4992 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.21718.21718.3 0.00471 Jul-60 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 -1 26531 21718 3 1807.932088 603.6483 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3937 - 4.86E+06 - - - 4.9438 - 1.658 0.34 - 54.2 1 2 0 0.0089 16 0 0 0 0.00E+00 0.00E+00 - - - 3.6255 0.9963 230117_WJC_METTL3_WT_vs_EV_F03.21719.21719.2 0.000621 20-Sep R.ASILNTWISLK[136.11].Q "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN" 2 1252.7271 1.8 26532 21719 2 1252.734279 627.3708 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 8.8 3937.1 - 4.72E+06 - - - 5.7523 - 1.954 0.424 - 347.7 1 2 0 0.0072 11 0 0 0 1.25E+07 6.97E+06 - - - 3.9826 1 230117_WJC_METTL3_WT_vs_EV_F03.21720.21720.2 8.51E-07 16/24 K.TPFLLVGTQIDLR.D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1471.8399 1.4 26533 21720 2 1471.844376 736.9272 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3937.1 - 4.43E+06 - - - 3.0649 - 3.203 0.606 - 1063.9 1 2 0 0.0045 13 0 0 0 8.52E+06 6.08E+06 - - - 6.5032 1 230117_WJC_METTL3_WT_vs_EV_F03.21721.21721.2 0.000165 15/24 K.TPFLLVGTQIDLR[166.11].D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1481.8481 -1 26534 21721 2 1481.852096 741.9313 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3937.2 - 3.10E+06 - - - 2.673 - 3.225 0.532 - 950.1 1 2 0 0.004 13 0 0 0 0.00E+00 0.00E+00 - - - 5.9743 0.9378 230117_WJC_METTL3_WT_vs_EV_F03.21722.21722.2 0.00769 16-Sep K.GVIDLIFEK.A "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 1032.5855 1.58 26535 21722 2 1032.59115 517.3001 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 3937.3 - 2.84E+06 - - - 5.4252 - 1.662 0.029 - 191.7 1 2 0 0.0056 9 0 0 0 5.51E+06 3.50E+06 - - - 0.7232 1 230117_WJC_METTL3_WT_vs_EV_F03.21723.21723.2 6.77E-06 14/22 K.VPGLYVIDSIVR.Q "sp|O95104|SCAF4_HUMAN,sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 3 1329.7656 -1 26536 21723 2 1329.770179 665.8901 SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3 5.81 3937.4 - 2.80E+06 - - - 3.4156 - 2.632 0.515 - 796.1 1 2 0 0.0045 12 0 0 0 0.00E+00 0.00E+00 - - - 5.3897 0.9893 230117_WJC_METTL3_WT_vs_EV_F03.21725.21725.2 0.0438 20-Nov R.TPGGVFLNLLK[136.11].N sp|Q9H814|PHAX_HUMAN 1 1165.695 1.06 26538 21725 2 1165.700867 583.8548 Phosphorylated adapter RNA export protein OS=Homo sapiens OX=9606 GN=PHAX PE=1 SV=1 8.41 3937.6 - 2.38E+06 - - - 4.9944 - 1.512 0.243 - 243.9 1 2 0 0.0058 11 0 0 0 5.29E+06 5.00E+06 - - - 1.9524 1 230117_WJC_METTL3_WT_vs_EV_F03.21726.21726.2 3.89E-07 14/22 K.VPGLYVIDSIVR[166.11].Q "sp|O95104|SCAF4_HUMAN,sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 3 1339.7739 -1 26539 21726 2 1339.779119 670.8942 SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3 5.81 3937.7 - 2.34E+06 - - - 3.8902 - 2.633 0.579 - 1001.3 1 2 0 0.0052 12 0 0 0 0.00E+00 0.00E+00 - - - 5.8632 0.9312 230117_WJC_METTL3_WT_vs_EV_F03.21727.21727.2 4.81E-05 24-Oct N.IVGLVGVDQFLVK[136.11].T sp|P13639|EF2_HUMAN 1 1393.8424 -1 26540 21727 2 1393.847608 697.9285 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3937.9 - 2.31E+06 - - - 3.7092 - 2.052 0.417 - 257.5 1 1 0 0.0052 13 0 0 0 0.00E+00 0.00E+00 - - - 3.9642 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.21728.21728.2 0.00097 18-Aug K.SLESFVELMK.T sp|Q6KB66|K2C80_HUMAN 1 1181.6002 999 26541 21728 2 1181.606273 591.8074 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 4.53 3938 - 2.23E+06 - - - 5.1303 - 1.801 0.377 - 157.6 1 2 0 0.0061 10 0 0 0 3.18E+06 0.00E+00 - - - 3.4659 1 230117_WJC_METTL3_WT_vs_EV_F03.21735.21735.2 6.76E-06 22-Sep K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 1449.51 26546 21735 2 1459.793356 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3938.6 - 1.33E+07 - - - 0.7604 - 2.309 0.501 - 336.2 1 2 0 0.0011 12 0 0 0 3.53E+08 2.44E+05 - - - 4.9428 1 230117_WJC_METTL3_WT_vs_EV_F03.21736.21736.2 3.50E-05 17/30 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 999 26547 21736 2 1796.007016 899.0095 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3938.6 - 1.03E+07 - - - 1.4766 - 3.656 0.62 - 1029.8 1 2 0 0.0027 16 0 0 0 2.21E+07 0.00E+00 - - - 6.8067 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21737.21737.2 0.00718 18-Sep K.FLLLQGLVEK.E "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 1158.7012 -1 26548 21737 2 1158.70259 580.3579 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 6 3938.7 - 3.13E+06 - - - 1.1599 - 1.841 0.375 - 248.3 1 2 0 0.0013 10 0 0 0 0.00E+00 0.00E+00 - - - 3.5139 0.9743 230117_WJC_METTL3_WT_vs_EV_F03.21741.21741.2 0.00369 12-Aug G.FGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 864.4989 -1 26552 21741 2 864.499784 433.2567 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3938.9 - 943520 - - - 1.0098 - 1.722 0.431 - 174.2 1 1 0 0.0009 7 0 0 0 0.00E+00 0.00E+00 - - - 3.9462 0.9746 230117_WJC_METTL3_WT_vs_EV_F03.21742.21742.2 0.00043 12-Sep G.FGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 856.4847 0.94 26553 21742 2 856.485226 429.2496 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3939 - 860439 - - - 0.6013 - 1.892 0.425 - 226.5 1 1 0 0.0005 7 0 0 0 1.77E+06 1.87E+06 - - - 4.2003 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.21755.21755.3 1.47E-05 Dec-44 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 -1 26565 21755 3 1459.793459 487.6047 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3940.3 - 3.20E+06 - - - 0.8309 - 2.396 0.368 - 328.4 1 2 0 0.0012 12 0 0 0 0.00E+00 0.00E+00 - - - 5.0645 0.9928 230117_WJC_METTL3_WT_vs_EV_F03.21758.21758.2 0.0516 12-Jun K.ELFSFFR.D "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 944.4756 -1 26568 21758 2 944.475546 473.2451 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6.1 3940.5 - 1.39E+06 - - - -0.0604 - 1.413 0.119 - 154.9 1 2 0 -0.0001 7 0 0 0 0.00E+00 0.00E+00 - - - 1.0153 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21759.21759.2 0.25 20-Dec K.LALGIPLPELR.N "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1190.7387 2.61 26569 21759 2 1190.740385 596.3766 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3940.6 - 1.25E+06 - - - 1.4201 - 2.638 0.3 - 422.7 1 2 0 0.0017 11 0 0 0 1.88E+07 7.22E+06 - - - 3.8804 0.996 230117_WJC_METTL3_WT_vs_EV_F03.21760.21760.2 0.537 12-Jun K.ELFSFFR[166.11].D "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 954.4839 -1 26570 21760 2 954.48453 478.2492 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6.1 3940.8 - 736685 - - - 0.6883 - 1.333 0.171 - 162.6 1 2 0 0.0007 7 0 0 0 0.00E+00 0.00E+00 - - - 1.2145 1 230117_WJC_METTL3_WT_vs_EV_F03.21763.21763.2 3.69E-07 15/26 K.LYSPSQIGAFVLMK.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1552.8323 5.52 26573 21763 2 1552.836348 777.4234 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3941.2 - 419299 - - - 2.583 - 2.725 0.59 - 762.3 1 2 0 0.004 14 0 0 0 5.51E+07 9.96E+06 - - - 5.9131 1 230117_WJC_METTL3_WT_vs_EV_F03.21774.21774.2 4.31E-07 18-Dec K.ADLTALFLPR[166.11].Q sp|Q13045|FLII_HUMAN 1 1125.6422 1.89 26583 21774 2 1125.644153 563.8284 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.88 3942.7 - 2.43E+06 - - - 1.7661 - 2.601 0.507 - 440.8 1 2 0 0.002 10 0 0 0 8.84E+06 4.66E+06 - - - 5.4533 0.9937 230117_WJC_METTL3_WT_vs_EV_F03.21779.21779.2 0.0864 20-Dec K.LALGIPLPELR[166.11].N "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1200.747 -1 26588 21779 2 1200.7488 601.3808 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3943.1 - 5.12E+06 - - - 1.529 - 1.889 0.006 - 469 1 2 0 0.0018 11 0 0 0 0.00E+00 0.00E+00 - - - 0.8054 1 230117_WJC_METTL3_WT_vs_EV_F03.21780.21780.2 5.31E-08 15/28 R.VLAFLSSVAGDALTR.H sp|Q92616|GCN1_HUMAN 1 1518.8406 -1 26589 21780 2 1518.841749 760.4276 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3943.1 - 3.14E+06 - - - 0.7611 - 2.521 0.569 - 490.8 1 2 0 0.0012 15 0 0 0 0.00E+00 0.00E+00 - - - 5.5166 0.999 230117_WJC_METTL3_WT_vs_EV_F03.21781.21781.2 0.00832 20-Oct K.AIVEFLSNLAR.H sp|Q13112|CAF1B_HUMAN 1 1231.6925 -1 26590 21781 2 1231.694967 616.8535 Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1 6.05 3943.2 - 3.11E+06 - - - 2.0257 - 2.061 0.212 - 331.4 1 2 0 0.0025 11 0 0 0 0.00E+00 0.00E+00 - - - 2.5625 1 230117_WJC_METTL3_WT_vs_EV_F03.21783.21783.2 3.55E-06 15/28 R.VLAFLSSVAGDALTR[166.11].H sp|Q92616|GCN1_HUMAN 1 1528.8489 -1 26592 21783 2 1528.848917 765.4317 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3943.5 - 2.71E+06 - - - 0.0353 - 3.019 0.565 - 795.1 1 2 0 0.0001 15 0 0 0 0.00E+00 0.00E+00 - - - 5.9306 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21784.21784.2 6.75E-05 20-Oct K.VVLPTFILEPR.S "sp|Q9BZF1|OSBL8_HUMAN,tr|F8VUA7|F8VUA7_HUMAN,tr|F8VQX7|F8VQX7_HUMAN" 3 1282.7649 -1 26593 21784 2 1282.768324 642.3897 Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3 5.97 3943.6 - 2.49E+06 - - - 2.6622 - 2.091 0.477 - 404.7 1 2 0 0.0034 11 0 0 0 0.00E+00 0.00E+00 - - - 4.5585 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.21788.21788.3 3.36E-05 Nov-72 K.VLLVGADNFTLLGKPLLGK.D "sp|Q7Z2W9|RM21_HUMAN,tr|H3BUY0|H3BUY0_HUMAN" 2 1967.1819 -1 26597 21788 3 1967.186514 656.7346 "39S ribosomal protein L21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL21 PE=1 SV=2" 8.56 3944.1 - 1.78E+06 - - - 2.3277 - 2.273 0.525 - 112.5 1 2 0 0.0046 19 0 0 0 0.00E+00 0.00E+00 - - - 6.4092 1 230117_WJC_METTL3_WT_vs_EV_F03.21791.21791.2 0.0148 17/26 K.QIALAVLSTELAVR[166.11].K "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1492.8852 -1 26600 21791 2 1492.890301 747.4499 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3944.5 - 1.29E+06 - - - 3.3841 - 2.417 0.472 - 552.6 1 2 0 0.0051 14 0 0 0 0.00E+00 0.00E+00 - - - 4.7403 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.21792.21792.2 0.00168 24-Oct R.NIIGVIPYFPYSK.Q "sp|Q14558|KPRA_HUMAN,tr|C9JKT9|C9JKT9_HUMAN,tr|B4DP31|B4DP31_HUMAN,tr|C9JNQ3|C9JNQ3_HUMAN,tr|C9JUN4|C9JUN4_HUMAN,tr|C9J168|C9J168_HUMAN" 6 1509.8232 -1 26601 21792 2 1509.820867 755.9189 Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Homo sapiens OX=9606 GN=PRPSAP1 PE=1 SV=2 8.5 3944.6 - 1.27E+06 - - - -1.5134 - 1.91 0.337 - 220.5 1 2 0 -0.0023 13 0 0 0 0.00E+00 0.00E+00 - - - 3.1902 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.21793.21793.2 0.0206 16-Nov R.DILALMEVK.M sp|Q96EK4|THA11_HUMAN 1 1030.5733 -1 26602 21793 2 1030.575486 516.2939 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 4.37 3944.8 - 1.16E+06 - - - 2.1522 - 2.096 0.252 - 355.4 1 2 0 0.0022 9 0 0 0 0.00E+00 0.00E+00 - - - 3.0425 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.21795.21795.2 0.186 26-Dec K.LAGLVEELEADEWR.F "sp|Q96DE5|APC16_HUMAN,tr|A0A087WUN5|A0A087WUN5_HUMAN" 2 1628.8046 -1 26603 21795 2 1628.800737 815.4096 Anaphase-promoting complex subunit 16 OS=Homo sapiens OX=9606 GN=ANAPC16 PE=1 SV=1 3.91 3945 - 265315 - - - -2.3729 - 2.569 0.425 - 520.5 1 2 0 -0.0039 14 0 0 0 0.00E+00 0.00E+00 - - - 4.5465 0.9731 230117_WJC_METTL3_WT_vs_EV_F03.21796.21796.2 0.000416 24-Aug R.NIFPSNLVSAAFR.S "sp|Q15758|AAAT_HUMAN,tr|M0QXM4|M0QXM4_HUMAN,tr|M0QX44|M0QX44_HUMAN" 3 1434.7619 0.92 26604 21796 2 1434.77291 718.3883 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 9.75 3945.1 - 199865 - - - 7.6396 - 1.804 0.29 - 149.7 1 2 0 0.011 13 0 0 0 3.02E+06 3.27E+06 - - - 2.6938 0.989 230117_WJC_METTL3_WT_vs_EV_F03.21797.21797.2 0.206 24-Jul R.LLDISASSTEQIL.- "sp|O43615|TIM44_HUMAN,tr|M0QXM9|M0QXM9_HUMAN" 2 1388.7399 - 26605 21797 2 1388.742744 695.3772 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.67 3945.1 - 6.02E+06 - - - 2.0652 - 1.407 0.078 - 154.8 1 2 0 0.0029 13 0 0 0 - - - - - 0.4926 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.21798.21798.2 8.17E-05 16-Aug R.NLPFDFTWK.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1166.576 2.69 26606 21798 2 1166.578343 584.2953 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3945.1 - 3.23E+06 - - - 1.969 - 1.601 0.275 - 195 1 2 0 0.0023 9 0 0 0 1.24E+08 4.63E+07 - - - 2.433 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.21799.21799.3 0.0041 Aug-52 K.LYSPSQIGAFVLMK.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1552.8323 4.55 26607 21799 3 1552.835759 518.6181 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3945.2 - 2.25E+06 - - - 2.2037 - 1.448 0.374 - 86.8 1 2 0 0.0034 14 0 0 0 1.17E+07 2.57E+06 - - - 3.6926 1 230117_WJC_METTL3_WT_vs_EV_F03.21800.21800.2 2.60E-07 13/26 K.LYSPSQIGAFVLMK[136.11].M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1560.8465 5.52 26608 21800 2 1560.849198 781.4305 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3945.2 - 1.69E+06 - - - 1.7048 - 2.866 0.599 - 551.3 1 2 0 0.0027 14 0 0 0 5.51E+07 9.96E+06 - - - 6.1066 1 230117_WJC_METTL3_WT_vs_EV_F03.21803.21803.2 3.03E-09 15/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 4.49 26611 21803 2 1591.948086 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3945.4 - 1.36E+06 - - - 1.9391 - 2.812 0.625 - 494.2 1 2 0 0.0031 15 0 0 0 7.37E+07 1.64E+07 - - - 6.1982 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21806.21806.2 0.00114 18-Aug R.LLELQYFISR[166.11].D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1290.7211 0.93 26614 21806 2 1290.723641 646.3678 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 6 3945.5 - 1.12E+06 - - - 1.9354 - 1.927 0.424 - 243.1 1 2 0 0.0025 10 0 0 0 2.93E+06 3.15E+06 - - - 4.0029 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.21808.21808.2 0.391 18-Sep R.LLELQYFISR.D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1280.7129 -1 26616 21808 2 1280.717394 641.3637 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 6 3945.6 - 1.03E+06 - - - 3.5301 - 1.9 0.355 - 316.5 1 2 0 0.0045 10 0 0 0 0.00E+00 0.00E+00 - - - 3.4532 1 230117_WJC_METTL3_WT_vs_EV_F03.21809.21809.2 0.00388 20-Nov K.DFAPVIVEAFK.H "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1234.6598 -1 26617 21809 2 1234.661095 618.3372 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.37 3945.7 - 995544 - - - 1.0691 - 2.023 0.494 - 360.6 1 2 0 0.0013 11 0 0 0 0.00E+00 0.00E+00 - - - 4.5953 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.21810.21810.2 0.000173 22-Sep R.TLITFAGMIPYR.T "sp|Q8N1F7|NUP93_HUMAN,tr|H3BV15|H3BV15_HUMAN" 2 1381.7428 -1 26618 21810 2 1381.746337 691.8787 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 8.41 3945.7 - 809839 - - - 2.5649 - 2.185 0.327 - 277.5 1 2 0 0.0035 12 0 0 0 0.00E+00 0.00E+00 - - - 3.5117 1 230117_WJC_METTL3_WT_vs_EV_F03.21811.21811.2 8.98E-08 15/32 R.AIGLSPMSFPTADLTLK.M "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1760.9383 -1 26619 21811 2 1760.939484 881.4764 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.88 3945.8 - 782357 - - - 0.6962 - 2.927 0.562 - 680.6 1 2 0 0.0012 17 0 0 0 0.00E+00 0.00E+00 - - - 5.832 1 230117_WJC_METTL3_WT_vs_EV_F03.21813.21813.2 5.89E-09 17/32 R.AIGLSPMSFPTADLTLK[136.11].M "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1768.9525 -1 26621 21813 2 1768.956619 885.4835 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.88 3945.9 - 525242 - - - 2.3522 - 3.226 0.612 - 864.4 1 2 0 0.0042 17 0 0 0 0.00E+00 0.00E+00 - - - 6.4395 0.9954 230117_WJC_METTL3_WT_vs_EV_F03.21817.21817.2 0.22 14-Aug K.ISLIQIFR.A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 988.607 -1 26624 21817 2 988.611369 495.3108 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.75 3946.6 - 1.40E+06 - - - 4.4679 - 1.875 0.204 - 185.2 1 2 0 0.0044 8 0 0 0 0.00E+00 0.00E+00 - - - 2.4422 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.21818.21818.3 2.65E-05 17/56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 4.41 26625 21818 3 1591.955278 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3946.7 - 4.29E+06 - - - 6.4569 - 3.111 0.485 - 290.9 1 2 0 0.0103 15 0 0 0 4.29E+07 9.72E+06 - - - 6.9059 0.9991 230117_WJC_METTL3_WT_vs_EV_F03.21819.21819.2 6.97E-05 16-Oct R.NLPFDFTWK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1174.5902 2.69 26626 21819 2 1174.594736 588.3024 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3946.8 - 3.53E+06 - - - 3.8226 - 1.789 0.464 - 294.4 1 2 0 0.0045 9 0 0 0 1.24E+08 4.63E+07 - - - 4.1495 0.9952 230117_WJC_METTL3_WT_vs_EV_F03.21820.21820.2 0.295 14-Aug K.ISLIQIFR[166.11].A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 998.6152 -1 26627 21820 2 998.620247 500.3149 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.75 3946.9 - 1.30E+06 - - - 5.032 - 1.884 0.256 - 182.3 1 2 0 0.005 8 0 0 0 0.00E+00 0.00E+00 - - - 2.8405 1 230117_WJC_METTL3_WT_vs_EV_F03.21823.21823.2 1.61E-09 14/24 K.MFVLDEADEMLSR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 11 1564.7141 -1 26630 21823 2 1564.721006 783.3643 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 3.92 3947.3 - 752695 - - - 4.4225 - 2.786 0.624 - 598.2 1 2 0 0.0069 13 0 0 0 0.00E+00 0.00E+00 - - - 6.2774 1 230117_WJC_METTL3_WT_vs_EV_F03.21825.21825.2 7.33E-08 14/24 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 1.94 26632 21825 2 1509.895462 755.9512 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3947.5 - 704131 - - - 5.0229 - 2.959 0.588 - 723.2 1 2 0 0.0076 13 0 0 0 2.34E+07 1.21E+07 - - - 6.1659 1 230117_WJC_METTL3_WT_vs_EV_F03.21826.21826.2 2.56E-15 17/26 R.FGDPEC[160.03]QVILPLLK.S sp|P22102|PUR2_HUMAN 1 1627.8644 1.08 26633 21826 2 1627.870181 814.9395 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.37 3947.7 - 665444 - - - 3.5728 - 3.47 0.689 - 796.3 1 2 0 0.0058 14 0 0 0 3.31E+06 3.06E+06 - - - 7.2503 1 230117_WJC_METTL3_WT_vs_EV_F03.21829.21829.2 1.17E-05 22-Nov K.LLPLVSDEVFIR.D sp|P11216|PYGB_HUMAN 1 1399.8075 19.49 26636 21829 2 1399.81437 700.911 "Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB PE=1 SV=5" 4.37 3948.1 - 483486 - - - 4.9064 - 2.304 0.54 - 403 1 2 0 0.0069 12 0 0 0 2.40E+06 1.23E+05 - - - 5.2234 1 230117_WJC_METTL3_WT_vs_EV_F03.21830.21830.2 0.021 14/28 R.ALVEVLGPYEPLLSR.V "sp|Q86VR2|RETR3_HUMAN,tr|K7EMF4|K7EMF4_HUMAN,tr|K7ELM8|K7ELM8_HUMAN,tr|K7EJ34|K7EJ34_HUMAN,tr|K7ENF4|K7ENF4_HUMAN,tr|K7ENZ6|K7ENZ6_HUMAN" 6 1654.9294 -1 26637 21830 2 1654.938304 828.472 Reticulophagy regulator 3 OS=Homo sapiens OX=9606 GN=RETREG3 PE=1 SV=1 4.53 3948.2 - 482398 - - - 5.3755 - 2.784 0.447 - 609.6 1 2 0 0.0089 15 0 0 0 0.00E+00 0.00E+00 - - - 4.857 0.9944 230117_WJC_METTL3_WT_vs_EV_F03.21831.21831.2 0.00347 18-Oct K.LLELQELVLR.L "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|A0A087WYC0|A0A087WYC0_HUMAN" 3 1224.7442 -1 26638 21831 2 1224.751675 613.3794 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 4.53 3948.3 - 462352 - - - 6.1245 - 2.289 0.315 - 316.4 1 2 0 0.0075 10 0 0 0 0.00E+00 0.00E+00 - - - 3.6768 1 230117_WJC_METTL3_WT_vs_EV_F03.21834.21834.2 0.0458 15/28 R.ALVEVLGPYEPLLSR[166.11].V "sp|Q86VR2|RETR3_HUMAN,tr|K7EMF4|K7EMF4_HUMAN,tr|K7ELM8|K7ELM8_HUMAN,tr|K7EJ34|K7EJ34_HUMAN,tr|K7ENF4|K7ENF4_HUMAN,tr|K7ENZ6|K7ENZ6_HUMAN" 6 1664.9377 -1 26641 21834 2 1664.946044 833.4761 Reticulophagy regulator 3 OS=Homo sapiens OX=9606 GN=RETREG3 PE=1 SV=1 4.53 3948.7 - 348452 - - - 5.0248 - 2.664 0.441 - 712.7 1 2 0 0.0084 15 0 0 0 0.00E+00 0.00E+00 - - - 4.7046 1 230117_WJC_METTL3_WT_vs_EV_F03.21840.21840.2 2.42E-06 13/28 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 4.49 26646 21840 2 1601.957609 801.9839 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3949.3 - 3.09E+06 - - - 2.7092 - 2.488 0.59 - 438.6 1 2 0 0.0043 15 0 0 0 7.37E+07 1.64E+07 - - - 5.6383 1 230117_WJC_METTL3_WT_vs_EV_F03.21844.21844.3 2.00E-06 16/48 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 1.86 26650 21844 3 1509.892546 504.3032 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3949.6 - 1.11E+06 - - - 3.0916 - 2.942 0.58 - 445.5 1 2 0 0.0047 13 0 0 0 4.30E+06 2.31E+06 - - - 7.9309 0.9781 230117_WJC_METTL3_WT_vs_EV_F03.21845.21845.2 0.968 18-Jun K.VLLDIFTGVR.L sp|P49916|DNLI3_HUMAN 1 1131.6652 2.78 26651 21845 2 1131.668272 566.8399 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 5.81 3949.6 - 986558 - - - 2.719 - 1.037 0.166 - 59 2 2 0 0.0031 10 0 0 0 2.43E+06 8.74E+05 - - - 0.2331 1 230117_WJC_METTL3_WT_vs_EV_F03.21846.21846.2 6.34E-08 13/24 R.IGLFYMDNDLITR[166.11].N "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN" 2 1579.7944 -1 26652 21846 2 1579.79789 790.9045 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.21 3949.7 - 929476 - - - 2.2186 - 2.809 0.643 - 679.2 1 2 0 0.0035 13 0 0 0 0.00E+00 0.00E+00 - - - 6.4399 1 230117_WJC_METTL3_WT_vs_EV_F03.21848.21848.2 5.51E-05 20-Dec K.DTLTYFIYSVK.N sp|O75446|SAP30_HUMAN 1 1348.6915 -1 26654 21848 2 1348.693158 675.353 Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1 5.83 3949.9 - 694317 - - - 1.2523 - 2.473 0.447 - 752.3 1 2 0 0.0017 11 0 0 0 0.00E+00 0.00E+00 - - - 4.7914 0.9952 230117_WJC_METTL3_WT_vs_EV_F03.21851.21851.2 0.559 16-Oct R.LLNILMQLR[166.11].K "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 1122.6823 -1 26657 21851 2 1122.685449 562.3484 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 9.75 3950.3 - 574561 - - - 2.845 - 2.149 0.021 - 224.7 1 2 0 0.0032 9 0 0 0 0.00E+00 0.00E+00 - - - 1.4083 1 230117_WJC_METTL3_WT_vs_EV_F03.21853.21853.2 1.30E-07 13/22 R.VFLALVEEVEDR.G "sp|Q9H3U1|UN45A_HUMAN,tr|A0A1W2PNX8|A0A1W2PNX8_HUMAN" 2 1417.7453 -1 26659 21853 2 1417.750492 709.8799 Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1 4 3950.4 - 547021 - - - 3.665 - 2.787 0.58 - 290.5 1 2 0 0.0052 12 0 0 0 0.00E+00 0.00E+00 - - - 6.0201 0.8766 230117_WJC_METTL3_WT_vs_EV_F03.21855.21855.2 0.00129 18-May R.LFPPQWIC[160.03]C[160.03]D.L sp|Q86U44|MTA70_HUMAN 1 1334.5788 - 26661 21855 2 1334.582125 668.2967 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.3 3950.7 - 418745 - - - 2.5176 - 1.258 0.333 - 75.8 1 1 0 0.0034 10 0 0 0 - - - - - 2.1402 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.21859.21859.2 0.0024 16-Sep K.ILNIFGVIK[136.11].G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1023.6572 1.56 26664 21859 2 1023.659612 512.8359 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3951.3 - 1.70E+06 - - - 2.3533 - 1.992 0.278 - 187.6 1 2 0 0.0024 9 0 0 0 9.90E+06 6.34E+06 - - - 3.0873 1 230117_WJC_METTL3_WT_vs_EV_F03.21861.21861.2 0.000181 13/24 R.NVIVLQTVLQEVR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1519.8961 -1 26666 21861 2 1519.899008 760.9554 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3951.4 - 4.93E+06 - - - 1.8817 - 2.685 0.499 - 620.2 1 2 0 0.0029 13 0 0 0 0.00E+00 0.00E+00 - - - 5.2606 1 230117_WJC_METTL3_WT_vs_EV_F03.21862.21862.2 1.74E-08 15/30 L.SLGLETAGGVMTALIK.R "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1559.8593 -1 26667 21862 2 1559.862397 780.9369 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.72 3951.4 - 2.53E+06 - - - 1.9983 - 3.072 0.618 - 624 1 1 0 0.0031 16 0 0 0 0.00E+00 0.00E+00 - - - 6.3639 0.9983 230117_WJC_METTL3_WT_vs_EV_F03.21863.21863.2 0.0654 16-Sep K.ILNIFGVIK.G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1015.643 -1 26668 21863 2 1015.645154 508.8288 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3951.5 - 2.45E+06 - - - 2.1179 - 1.957 0.137 - 183.5 1 2 0 0.0022 9 0 0 0 0.00E+00 0.00E+00 - - - 1.9946 1 230117_WJC_METTL3_WT_vs_EV_F03.21864.21864.3 1.95E-07 15/48 K.LFYADHPFIFLVR.D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1636.8766 3.42 26669 21864 3 1636.880271 546.6328 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3951.5 - 2.38E+06 - - - 2.2518 - 3.029 0.579 - 244.1 1 2 0 0.0037 13 0 0 0 3.26E+07 9.56E+06 - - - 7.999 1 230117_WJC_METTL3_WT_vs_EV_F03.21865.21865.3 8.99E-05 16/56 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 4.41 26670 21865 3 1601.956422 534.9917 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3951.6 - 2.36E+06 - - - 1.9682 - 3.071 0.52 - 220.6 1 2 0 0.0032 15 0 0 0 4.29E+07 9.72E+06 - - - 7.2643 1 230117_WJC_METTL3_WT_vs_EV_F03.21870.21870.2 1.94E-06 22-Dec R.NMLQFNLQILPK[136.11].S "sp|O15371|EIF3D_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 3 1465.8207 -1 26675 21870 2 1465.826876 733.9176 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 8.75 3952 - 901822 - - - 4.2434 - 2.526 0.533 - 433.9 1 2 0 0.0062 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4139 1 230117_WJC_METTL3_WT_vs_EV_F03.21874.21874.2 3.74E-05 Dec-32 R.LTSIIFAEDITTGQVLR.C sp|Q8TEM1|PO210_HUMAN 1 1876.0306 -1 26679 21874 2 1876.033331 939.0226 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.37 3952.5 - 448000 - - - 1.4669 - 2.832 0.595 - 387.4 1 2 0 0.0028 17 0 0 0 0.00E+00 0.00E+00 - - - 5.9941 1 230117_WJC_METTL3_WT_vs_EV_F03.21875.21875.2 6.65E-08 26-Nov R.LPLPYGFSAMQGWR.V sp|O15355|PPM1G_HUMAN 1 1621.8075 -1 26680 21875 2 1621.809231 811.911 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 8.75 3952.6 - 404077 - - - 1.0556 - 2.019 0.579 - 327.3 1 2 0 0.0017 14 0 0 0 0.00E+00 0.00E+00 - - - 5.0801 1 230117_WJC_METTL3_WT_vs_EV_F03.21876.21876.2 1.27E-06 26-Nov R.IVEPYVTWGFPNLK.S "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1661.8817 0.82 26681 21876 2 1661.885891 831.9481 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6 3952.7 - 390664 - - - 2.5038 - 2.342 0.53 - 319.4 1 2 0 0.0042 14 0 0 0 2.09E+06 2.56E+06 - - - 5.0898 1 230117_WJC_METTL3_WT_vs_EV_F03.21879.21879.2 4.89E-10 14/28 K.YFDTVPVAAAMC[160.03]VLK.T sp|Q15393|SF3B3_HUMAN 1 1683.8364 1.43 26683 21879 2 1683.837332 842.9255 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.83 3953.1 - 833798 - - - 0.5321 - 2.821 0.584 - 456.5 1 2 0 0.0009 15 0 0 0 2.87E+06 2.01E+06 - - - 5.9039 1 230117_WJC_METTL3_WT_vs_EV_F03.21880.21880.2 1.72E-08 14/26 R.IVEPYVTWGFPNLK[136.11].S "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1669.8959 -1 26684 21880 2 1669.903314 835.9552 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6 3953.2 - 1.13E+06 - - - 4.4218 - 2.51 0.591 - 574.6 1 2 0 0.0074 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7132 1 230117_WJC_METTL3_WT_vs_EV_F03.21881.21881.3 9.66E-08 Dec-48 K.LFYADHPFIFLVR[166.11].D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1646.8849 3.42 26685 21881 3 1646.887318 549.9689 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3953.2 - 5.03E+06 - - - 1.4956 - 2.668 0.594 - 153.9 1 2 0 0.0025 13 0 0 0 3.26E+07 9.56E+06 - - - 7.8225 1 230117_WJC_METTL3_WT_vs_EV_F03.21882.21882.2 5.17E-07 20-Oct K.SVFGGLVNYFK.S "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1229.6445 -1 26686 21882 2 1229.647128 615.8295 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 8.31 3953.3 - 3.05E+06 - - - 2.1705 - 2.135 0.476 - 278.7 1 2 0 0.0027 11 0 0 0 0.00E+00 0.00E+00 - - - 4.6077 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.21883.21883.3 0.00265 14/40 K.ILDVEIIFNER[166.11].G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1369.7481 1.24 26687 21883 3 1369.750363 457.59 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3953.3 - 2.15E+06 - - - 1.6616 - 2.263 0.371 - 372.9 1 2 0 0.0023 11 0 0 0 4.17E+06 3.36E+06 - - - 4.9957 0.9801 230117_WJC_METTL3_WT_vs_EV_F03.21884.21884.2 0.000219 26-Dec K.LSPVVGAVYGPELY.A "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 7 1462.7708 - 26688 21884 2 1462.77258 732.3927 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4 3953.4 - 2.06E+06 - - - 1.2292 - 2.287 0.464 - 434.7 1 1 0 0.0018 14 0 0 0 - - - - - 4.5435 1 230117_WJC_METTL3_WT_vs_EV_F03.21887.21887.2 0.00541 15/24 R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 26691 21887 2 1349.793321 675.9026 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3953.6 - 1.81E+06 - - - 2.0011 - 2.864 0.458 - 668.8 1 2 0 0.0027 13 0 0 0 0.00E+00 0.00E+00 - - - 5.1235 1 230117_WJC_METTL3_WT_vs_EV_F03.21888.21888.2 1.61E-06 20-Nov K.SVFGGLVNYFK[136.11].S "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1237.6587 1.3 26692 21888 2 1237.660731 619.8366 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 8.31 3953.7 - 1.59E+06 - - - 1.6741 - 2.115 0.53 - 289.4 1 2 0 0.0021 11 0 0 0 7.63E+06 5.85E+06 - - - 4.9813 1 230117_WJC_METTL3_WT_vs_EV_F03.21889.21889.2 0.000479 22-Dec R.NMLQFNLQILPK.S "sp|O15371|EIF3D_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 3 1457.8065 -1 26693 21889 2 1457.808359 729.9105 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 8.75 3953.8 - 1.53E+06 - - - 1.3054 - 2.543 0.514 - 572.3 1 2 0 0.0019 12 0 0 0 0.00E+00 0.00E+00 - - - 5.2926 1 230117_WJC_METTL3_WT_vs_EV_F03.21890.21890.3 5.01E-06 16/48 R.VNILEVASGAVLR.S sp|Q12788|TBL3_HUMAN 1 1339.7823 -1 26694 21890 3 1339.784197 447.6014 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3953.9 - 1.43E+06 - - - 1.3786 - 3.068 0.529 - 462.1 1 2 0 0.0018 13 0 0 0 0.00E+00 0.00E+00 - - - 7.4767 1 230117_WJC_METTL3_WT_vs_EV_F03.21891.21891.2 0.000595 18-Sep R.LGIYTVLFER.L "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 1209.6758 -1 26695 21891 2 1209.680865 605.8452 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 6 3953.9 - 1.37E+06 - - - 4.2201 - 2.141 0.472 - 234.3 1 2 0 0.0051 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6505 1 230117_WJC_METTL3_WT_vs_EV_F03.21892.21892.3 1.50E-07 16/48 R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 26696 21892 3 1349.792566 450.9375 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3954 - 1.20E+06 - - - 1.4417 - 3.259 0.469 - 428.2 1 2 0 0.0019 13 0 0 0 0.00E+00 0.00E+00 - - - 6.9715 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21893.21893.2 7.70E-06 20-Nov K.ATLWYVPLSLK.N "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1289.7384 -1 26697 21893 2 1289.741601 645.8765 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 8.63 3954.1 - 1.09E+06 - - - 2.5129 - 1.973 0.436 - 429.6 1 2 0 0.0032 11 0 0 0 0.00E+00 0.00E+00 - - - 4.0986 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.21895.21895.2 3.77E-05 24-Dec K.SIIGVIPYFPYSK.Q "sp|O60256|KPRB_HUMAN,tr|C9JJS3|C9JJS3_HUMAN,tr|C9JDU5|C9JDU5_HUMAN,tr|E7EPA1|E7EPA1_HUMAN,tr|E7EW35|E7EW35_HUMAN,tr|C9JDH0|C9JDH0_HUMAN,tr|C9K0K7|C9K0K7_HUMAN" 7 1482.8123 -1 26699 21895 2 1482.811692 742.4134 Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Homo sapiens OX=9606 GN=PRPSAP2 PE=1 SV=1 8.22 3954.4 - 1.03E+06 - - - -0.3783 - 1.952 0.509 - 446.9 1 2 0 -0.0006 13 0 0 0 0.00E+00 0.00E+00 - - - 4.5169 1 230117_WJC_METTL3_WT_vs_EV_F03.21898.21898.2 0.000219 13/24 K.LFYADHPFIFLVR.D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1636.8766 1.46 26702 21898 2 1636.881982 819.4456 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3954.8 - 847419 - - - 3.2971 - 2.504 0.483 - 363.7 1 2 0 0.0054 13 0 0 0 2.04E+06 1.40E+06 - - - 4.9625 0.9957 230117_WJC_METTL3_WT_vs_EV_F03.21905.21905.2 2.27E-05 14/24 K.LAGFLDLTEQEFR[166.11].L "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 1547.7859 1.82 26708 21905 2 1547.794341 774.9002 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.14 3955.2 - 1.77E+06 - - - 5.4349 - 2.497 0.265 - 740.8 1 2 0 0.0084 13 0 0 0 3.99E+07 2.19E+07 - - - 3.3443 1 230117_WJC_METTL3_WT_vs_EV_F03.21906.21906.2 1.96E-06 24-Dec K.LGAGTFQLDQWLR.A sp|P50219|MNX1_HUMAN 1 1503.7834 -1 26709 21906 2 1503.786368 752.899 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 5.84 3955.3 - 1.72E+06 - - - 1.965 - 2.827 0.462 - 485.2 1 2 0 0.003 13 0 0 0 0.00E+00 0.00E+00 - - - 5.1196 1 230117_WJC_METTL3_WT_vs_EV_F03.21907.21907.2 4.59E-05 15/24 K.LAGFLDLTEQEFR.L "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 1537.7777 -1 26710 21907 2 1537.780195 769.8961 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.14 3955.4 - 1.57E+06 - - - 1.6491 - 3.168 0.505 - 940.7 1 2 0 0.0025 13 0 0 0 0.00E+00 0.00E+00 - - - 5.7296 0.9917 230117_WJC_METTL3_WT_vs_EV_F03.21908.21908.2 0.0425 20-Sep K.FVSISDLLVPK[136.11].D sp|P50395|GDIB_HUMAN 1 1224.7209 -1 26711 21908 2 1224.72623 613.3677 Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2 5.84 3955.4 - 1.22E+06 - - - 4.3316 - 1.439 0.236 - 140.1 1 2 0 0.0053 11 0 0 0 0.00E+00 0.00E+00 - - - 1.767 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.21909.21909.2 0.00269 14-Sep R.TLFLELIR.A sp|Q96GM8|TOE1_HUMAN 1 1003.6066 1.53 26712 21909 2 1003.608659 502.8106 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 5.66 3955.5 - 1.14E+06 - - - 2.0347 - 1.699 0.29 - 336 1 2 0 0.002 8 0 0 0 3.50E+06 2.29E+06 - - - 2.7809 1 230117_WJC_METTL3_WT_vs_EV_F03.21911.21911.2 0.000931 14/24 R.IESILMSLPLTAR.W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1442.8167 1.29 26714 21911 2 1442.819742 722.4156 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3955.8 - 991965 - - - 2.1174 - 2.681 0.445 - 902.9 1 2 0 0.0031 13 0 0 0 1.60E+07 1.23E+07 - - - 4.8579 1 230117_WJC_METTL3_WT_vs_EV_F03.21912.21912.3 9.34E-05 Dec-48 K.FDTPFLPKPLFFR.R sp|Q14684|RRP1B_HUMAN 1 1623.8813 0.47 26715 21912 3 1623.882248 542.3011 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 8.75 3955.8 - 792418 - - - 0.5616 - 2.373 0.511 - 114.8 1 2 0 0.0009 13 0 0 0 2.99E+06 6.35E+06 - - - 6.5799 1 230117_WJC_METTL3_WT_vs_EV_F03.21915.21915.2 0.0742 14/26 K.LDDIFEPVLIPEPK.L "sp|Q14008|CKAP5_HUMAN,tr|H0YEK7|H0YEK7_HUMAN,tr|H0YCF6|H0YCF6_HUMAN" 3 1623.876 -1 26718 21915 2 1623.879903 812.9453 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 3.92 3956.1 - 644748 - - - 2.4183 - 2.625 0.56 - 640 1 2 0 0.0039 14 0 0 0 0.00E+00 0.00E+00 - - - 5.5977 0.9032 230117_WJC_METTL3_WT_vs_EV_F03.21917.21917.2 0.0163 20-Sep K.IIHDFPQFYPL.G "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 1388.7129 - 26720 21917 2 1388.713464 695.3637 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 5.08 3956.3 - 447080 - - - 0.4256 - 1.507 0.287 - 188.7 1 1 0 0.0006 11 0 0 0 - - - - - 2.2701 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.21919.21919.2 0.00539 28-Jul K.YFDTVPVAAAMC[160.03]VLK[136.11].T sp|Q15393|SF3B3_HUMAN 1 1691.8506 -1 26722 21919 2 1691.851065 846.9326 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.83 3956.6 - 389645 - - - 0.2536 - 1.385 0.415 - 96.3 1 2 0 0.0004 15 0 0 0 0.00E+00 0.00E+00 - - - 2.9068 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.21922.21922.2 0.0311 26-Nov K.LDDIFEPVLIPEPK[136.11].L "sp|Q14008|CKAP5_HUMAN,tr|H0YEK7|H0YEK7_HUMAN,tr|H0YCF6|H0YCF6_HUMAN" 3 1631.8902 -1 26724 21922 2 1631.893549 816.9524 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 3.92 3956.9 - 543235 - - - 2.0669 - 1.3 0.359 - 135.1 1 2 0 0.0034 14 0 0 0 0.00E+00 0.00E+00 - - - 2.3499 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21924.21924.2 0.00577 20-Nov K.GFLSGLLDNVK.Q "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1161.6394 2.84 26726 21924 2 1161.641191 581.827 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.84 3957 - 1.11E+07 - - - 1.5642 - 2.158 0.384 - 385.3 1 2 0 0.0018 11 0 0 0 3.72E+07 1.31E+07 - - - 3.9575 1 230117_WJC_METTL3_WT_vs_EV_F03.21925.21925.2 7.40E-05 20-Oct K.LILPELGPVFK[136.11].Q "sp|Q6P3W7|SCYL2_HUMAN,tr|H0YIK6|H0YIK6_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 1232.7624 0.69 26727 21925 2 1232.762558 617.3885 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6 3957 - 6.36E+06 - - - 0.1314 - 2.111 0.533 - 334.7 1 2 0 0.0002 11 0 0 0 2.93E+07 4.22E+07 - - - 4.9989 0.9713 230117_WJC_METTL3_WT_vs_EV_F03.21926.21926.2 1.5 24-Apr K.AFTYSSTLISHK[136.11]R[166.11].L sp|A8MUV8|ZN727_HUMAN 1 1527.8164 0.01 26728 21926 2 1527.819272 764.9155 Putative zinc finger protein 727 OS=Homo sapiens OX=9606 GN=ZNF727 PE=5 SV=3 9.99 3957.1 - 6.34E+06 - - - 1.849 - 1.004 0.131 - 40.5 3 2 0 0.0028 13 0 0 0 4.96E+05 4.07E+07 - - - -0.1952 1 230117_WJC_METTL3_WT_vs_EV_F03.21930.21930.2 0.000147 15/22 K.SLVALLVETQMK[136.11].K "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1338.7672 -1 26732 21930 2 1338.768814 670.3909 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.72 3957.3 - 2.86E+06 - - - 1.1877 - 2.976 0.475 - 978.3 1 2 0 0.0016 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4184 1 230117_WJC_METTL3_WT_vs_EV_F03.21932.21932.2 0.0157 20-Dec K.DVLLPWYNAYR.F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1408.7139 -1 26734 21932 2 1408.714068 705.3642 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3957.4 - 2.33E+06 - - - 0.0937 - 2.248 0.46 - 494.1 1 2 0 0.0001 11 0 0 0 0.00E+00 0.00E+00 - - - 4.6299 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.21933.21933.3 0.00012 14/48 R.IESILMSLPLTAR.W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1442.8167 1.26 26735 21933 3 1442.817456 481.9462 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3957.5 - 2.09E+06 - - - 0.533 - 2.715 0.475 - 253.5 1 2 0 0.0008 13 0 0 0 6.12E+06 4.85E+06 - - - 6.5436 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.21935.21935.3 1.57E-05 13/48 R.IESILMSLPLTAR[166.11].W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1452.825 1.35 26737 21935 3 1452.824798 485.2823 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3957.6 - 1.83E+06 - - - -0.1094 - 2.712 0.46 - 235.1 1 2 0 -0.0002 13 0 0 0 6.53E+06 4.85E+06 - - - 6.3735 1 230117_WJC_METTL3_WT_vs_EV_F03.21936.21936.2 1.36E-06 20-Dec K.DVLLPWYNAYR[166.11].F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1418.7222 -1 26738 21936 2 1418.724724 710.3684 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3957.7 - 1.61E+06 - - - 1.7748 - 2.315 0.559 - 505.9 1 2 0 0.0025 11 0 0 0 0.00E+00 0.00E+00 - - - 5.4398 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.21938.21938.3 0.00207 22/60 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 1.17 26740 21938 3 1663.94967 555.6576 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3957.8 - 1.34E+06 - - - -0.7224 - 3.644 0.504 - 520.7 1 2 0 -0.0012 16 0 0 0 1.07E+07 9.12E+06 - - - 7.4766 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.21943.21943.3 2.07E-06 13/52 K.LLPVLVHTFWIDTK.N sp|Q13505|MTX1_HUMAN 1 1680.9603 1.46 26744 21943 3 1680.968251 561.3274 Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1 PE=1 SV=3 6.74 3958.3 - 1.60E+06 - - - 4.7217 - 2.642 0.552 - 186 1 2 0 0.0079 14 0 0 0 4.89E+06 3.35E+06 - - - 7.2739 1 230117_WJC_METTL3_WT_vs_EV_F03.21944.21944.2 6.58E-05 18-Nov K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 999 26745 21944 2 1146.629953 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3958.4 - 1.59E+07 - - - 1.289 - 2.095 0.501 - 334 1 2 0 0.0015 10 0 0 0 8.07E+07 0.00E+00 - - - 4.8052 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.21949.21949.3 2.83E-07 15/60 K.INEAIVAVQAIIADPK[136.11].T sp|Q9Y224|RTRAF_HUMAN 1 1671.9651 1.17 26750 21949 3 1671.963846 558.329 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3958.7 - 3.57E+06 - - - -0.7333 - 2.734 0.544 - 198.9 1 2 0 -0.0012 16 0 0 0 1.07E+07 9.12E+06 - - - 7.1854 1 230117_WJC_METTL3_WT_vs_EV_F03.21950.21950.2 7.05E-10 22/34 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 7.93 26751 21950 2 1911.945576 956.9806 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3958.7 - 3.28E+06 - - - -0.5225 - 4.303 0.644 - 1946 1 2 0 -0.001 18 0 0 0 9.02E+07 1.14E+07 - - - 7.3851 1 230117_WJC_METTL3_WT_vs_EV_F03.21953.21953.2 4.71E-10 20/30 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 1.48 26754 21953 2 1663.946692 832.9827 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3959 - 2.25E+06 - - - -2.5121 - 3.641 0.516 - 1438 1 2 0 -0.0042 16 0 0 0 7.00E+06 4.73E+06 - - - 6.0279 1 230117_WJC_METTL3_WT_vs_EV_F03.21954.21954.2 2.67E-05 20/30 K.INEAIVAVQAIIADPK[136.11].T sp|Q9Y224|RTRAF_HUMAN 1 1671.9651 1.48 26755 21954 2 1671.961722 836.9898 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3959.1 - 1.39E+06 - - - -2.0036 - 3.595 0.515 - 1227.2 1 2 0 -0.0034 16 0 0 0 7.00E+06 4.73E+06 - - - 5.9896 0.9591 230117_WJC_METTL3_WT_vs_EV_F03.21956.21956.2 0.00723 14-Sep A.AQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 928.5229 5.04 26757 21956 2 928.523083 465.2687 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3959.3 - 1.20E+06 - - - 0.1465 - 1.931 0.348 - 448.5 1 1 0 0.0001 8 0 0 0 3.83E+06 7.61E+05 - - - 3.5959 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.21963.21963.2 1.26E-05 22-Dec K.FPTYPVPHYSFF.- sp|Q96SI9|STRBP_HUMAN 1 1500.7078 - 26762 21963 2 1500.710093 751.3612 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 6.74 3960.2 - 2.98E+06 - - - 1.5359 - 2.22 0.243 - 373.7 1 2 0 0.0023 12 0 0 0 - - - - - 2.9335 1 230117_WJC_METTL3_WT_vs_EV_F03.21966.21966.2 6.82E-09 19/34 K.LGGSLADSYLDEGFLLDK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1919.9608 7.93 26765 21966 2 1919.959042 960.9877 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3960.6 - 2.14E+06 - - - -0.9026 - 4.037 0.617 - 1526.8 1 2 0 -0.0017 18 0 0 0 9.02E+07 1.14E+07 - - - 7.0285 0.9307 230117_WJC_METTL3_WT_vs_EV_F03.21967.21967.2 0.137 18-Sep K.ANINVENAFF.T sp|P61006|RAB8A_HUMAN 1 1137.5455 - 26766 21967 2 1137.548552 569.78 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 4 3960.7 - 1.91E+06 - - - 2.7058 - 1.838 0.301 - 145.9 1 1 0 0.0031 10 0 0 0 - - - - - 2.9622 1 230117_WJC_METTL3_WT_vs_EV_F03.21968.21968.3 2.61E-07 15/52 K.VVIGMDVAASEFFR.S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1539.7756 1.87 26767 21968 3 1539.779854 514.2658 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.37 3960.9 - 1.44E+06 - - - 2.7952 - 2.926 0.539 - 323.9 1 2 0 0.0043 14 0 0 0 6.40E+06 3.42E+06 - - - 7.4013 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.21974.21974.3 2.17E-06 14/68 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 5.42 26771 21974 3 1911.950166 638.3228 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3961.6 - 4.36E+06 - - - 1.8782 - 2.315 0.5 - 172.3 1 2 0 0.0036 18 0 0 0 1.61E+07 2.97E+06 - - - 6.2037 1 230117_WJC_METTL3_WT_vs_EV_F03.21977.21977.3 1.92E-06 15/44 R.FFALPYVDHFLR[166.11].L sp|Q9HD33|RM47_HUMAN 1 1533.8008 0.8 26774 21977 3 1533.80428 512.2742 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 6.74 3961.8 - 1.95E+06 - - - 2.2747 - 2.441 0.575 - 234.8 1 2 0 0.0035 12 0 0 0 6.68E+06 8.30E+06 - - - 7.4233 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.21978.21978.2 1.07E-05 15/22 R.LTLAELNQILYR[166.11].C sp|P35573|GDE_HUMAN 1 1455.8325 1.36 26775 21978 2 1455.836761 728.9235 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 6 3961.9 - 1.79E+06 - - - 2.9372 - 3.056 0.352 - 1303.5 1 2 0 0.0043 12 0 0 0 8.34E+06 6.12E+06 - - - 4.5788 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.21981.21981.3 2.33E-07 17/44 R.FFALPYVDHFLR.L sp|Q9HD33|RM47_HUMAN 1 1523.7925 0.81 26778 21981 3 1523.794881 508.9381 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 6.74 3962.2 - 1.61E+06 - - - 1.5488 - 2.822 0.377 - 302.9 1 2 0 0.0024 12 0 0 0 6.63E+06 8.17E+06 - - - 5.6182 1 230117_WJC_METTL3_WT_vs_EV_F03.21982.21982.3 3.62E-11 21/64 K.LPIFFFGTHETAFLGPK.D sp|O75475|PSIP1_HUMAN 1 1921.0138 0.77 26779 21982 3 1921.024718 641.3452 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 6.75 3962.2 - 1.23E+06 - - - 5.6798 - 3.884 0.569 - 571.2 1 2 0 0.0109 17 0 0 0 4.47E+06 5.79E+06 - - - 8.3086 0.9865 230117_WJC_METTL3_WT_vs_EV_F03.21983.21983.2 0.0305 16-Aug K.VSLPLFDFK[136.11].R sp|O00443|P3C2A_HUMAN 1 1072.6048 1.17 26780 21983 2 1072.610804 537.3097 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 5.81 3962.3 - 1.22E+06 - - - 5.5668 - 1.746 0.196 - 139.3 1 2 0 0.006 9 0 0 0 6.88E+06 5.86E+06 - - - 2.0992 1 230117_WJC_METTL3_WT_vs_EV_F03.21984.21984.2 9.01E-12 18/28 K.AVLDSYEYFAVLAAK.E sp|P82664|RT10_HUMAN 1 1658.8556 -1 26781 21984 2 1658.858044 830.4351 "28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2" 4.37 3962.5 - 1.21E+06 - - - 1.4884 - 3.301 0.689 - 903.1 1 2 0 0.0025 15 0 0 0 0.00E+00 0.00E+00 - - - 7.0652 1 230117_WJC_METTL3_WT_vs_EV_F03.21985.21985.2 2.91E-05 26-Dec R.GVSVWPVGLVGGLR[166.11].F "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN" 2 1404.8117 0.85 26782 21985 2 1404.815023 703.4131 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 9.75 3962.6 - 1.01E+06 - - - 2.3726 - 2.276 0.479 - 267.8 1 2 0 0.0033 14 0 0 0 7.92E+06 9.33E+06 - - - 4.6417 1 230117_WJC_METTL3_WT_vs_EV_F03.21996.21996.2 2.35E-08 13/20 K.VMVQPINLIFR.Y sp|P62304|RUXE_HUMAN 1 1328.7639 -1 26792 21996 2 1328.764902 665.3892 Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1 9.72 3963.9 - 3.34E+07 - - - 0.7819 - 2.689 0.559 - 545 1 2 0 0.001 11 0 0 0 0.00E+00 0.00E+00 - - - 5.8454 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.21997.21997.2 0.00769 20-Oct K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 999 26793 21997 2 1106.548053 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3964 - 5.68E+06 - - - 1.492 - 2.148 0.373 - 238.9 1 2 0 0.0017 11 0 0 0 1.27E+07 0.00E+00 - - - 3.8637 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.21999.21999.2 3.29E-05 16-Sep R.C[160.03]LLAYFLDK.S "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1141.5842 41.55 26795 21999 2 1141.588507 571.7994 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 5.83 3964.1 - 2.86E+06 - - - 3.8009 - 2.081 0.279 - 264.6 1 2 0 0.0043 9 0 0 0 1.59E+07 3.83E+05 - - - 3.2205 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.22002.22002.2 0.00363 20-Nov R.IAFWDDVYGFK.M sp|O60678|ANM3_HUMAN 1 1359.6499 -1 26798 22002 2 1359.649339 680.8322 Protein arginine N-methyltransferase 3 OS=Homo sapiens OX=9606 GN=PRMT3 PE=1 SV=4 4.21 3964.4 - 1.86E+06 - - - -0.4413 - 1.932 0.395 - 367.2 1 2 0 -0.0006 11 0 0 0 0.00E+00 0.00E+00 - - - 3.7398 0.9922 230117_WJC_METTL3_WT_vs_EV_F03.22006.22006.2 0.14 18-Aug R.VSFC[160.03]PLSLWR[166.11].W sp|O96005|CLPT1_HUMAN 1 1273.6517 0.45 26802 22006 2 1273.655375 637.8331 Cleft lip and palate transmembrane protein 1 OS=Homo sapiens OX=9606 GN=CLPTM1 PE=1 SV=1 8.22 3964.9 - 1.27E+06 - - - 2.898 - 1.434 0.136 - 129.3 1 2 0 0.0037 10 0 0 0 8.71E+06 1.92E+07 - - - 1.0505 0.9826 230117_WJC_METTL3_WT_vs_EV_F03.22009.22009.2 0.0713 28-Oct R.GALINVPPPFLGLPR[166.11].F "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN" 2 1569.9271 -1 26805 22009 2 1569.923958 785.9708 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 9.75 3965.3 - 659046 - - - -1.9721 - 1.577 0.148 - 185.1 1 2 0 -0.0031 15 0 0 0 0.00E+00 0.00E+00 - - - 1.2531 1 230117_WJC_METTL3_WT_vs_EV_F03.22018.22018.2 2.41E-08 16/26 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.27 26812 22018 2 1676.899431 839.4565 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3966.4 - 1.86E+07 - - - 0.554 - 3.259 0.544 - 953.1 1 2 0 0.0009 14 0 0 0 7.87E+07 6.21E+07 - - - 6.0234 1 230117_WJC_METTL3_WT_vs_EV_F03.22019.22019.2 4.87E-08 15/26 M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 1.27 26813 22019 2 1686.907664 844.4607 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3966.4 - 1.49E+07 - - - 0.5288 - 3.219 0.582 - 885 1 2 0 0.0009 14 0 0 0 7.87E+07 6.21E+07 - - - 6.2731 1 230117_WJC_METTL3_WT_vs_EV_F03.22023.22023.2 8.32E-10 13/22 K.LIC[160.03]C[160.03]DILDVLDK.H "sp|P62258|1433E_HUMAN,tr|K7EIT4|K7EIT4_HUMAN" 2 1475.7364 -1 26817 22023 2 1475.73696 738.8755 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 3.93 3966.6 - 7.14E+06 - - - 0.3876 - 2.652 0.661 - 559.2 1 2 0 0.0006 12 0 0 0 0.00E+00 0.00E+00 - - - 6.4892 1 230117_WJC_METTL3_WT_vs_EV_F03.22024.22024.2 5.05E-06 20-Nov K.TFSFAIPLIEK[136.11].L sp|Q9NR30|DDX21_HUMAN 1 1272.7209 1 26818 22024 2 1272.722308 637.3677 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.66 3966.6 - 7.02E+06 - - - 1.0866 - 1.927 0.523 - 277.1 1 2 0 0.0014 11 0 0 0 7.17E+07 7.13E+07 - - - 4.678 0.9834 230117_WJC_METTL3_WT_vs_EV_F03.22025.22025.2 0.394 20-May K.DLTNVQNLQK[136.11]K[136.11].H "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1315.7431 -1 26819 22025 2 1315.742702 658.8788 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.59 3966.7 - 6.16E+06 - - - -0.2751 - 0.904 0.234 - 31.3 1 2 0 -0.0004 11 0 0 0 0.00E+00 0.00E+00 - - - 0.4962 1 230117_WJC_METTL3_WT_vs_EV_F03.22026.22026.3 1.10E-07 Nov-52 M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 1.31 26820 22026 3 1686.908038 563.3095 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3966.7 - 5.90E+06 - - - 0.7505 - 2.657 0.507 - 161.2 1 2 0 0.0013 14 0 0 0 2.46E+07 1.88E+07 - - - 6.7891 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22028.22028.2 2.03E-05 15/24 R.ALTLGALTLPLAR.L sp|Q9BSJ8|ESYT1_HUMAN 1 1308.8129 -1 26822 22028 2 1308.814504 655.4137 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 9.79 3966.8 - 5.49E+06 - - - 1.2087 - 2.801 0.389 - 924.7 1 2 0 0.0016 13 0 0 0 0.00E+00 0.00E+00 - - - 4.5571 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.22029.22029.2 0.00502 16-Oct K.AGLVELLLR.E "sp|Q13425|SNTB2_HUMAN,tr|A0A140TA73|A0A140TA73_HUMAN" 2 982.6175 -1 26823 22029 2 982.617775 492.316 Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1 6.05 3966.9 - 3.80E+06 - - - 0.2636 - 2.384 0.356 - 343 1 2 0 0.0003 9 0 0 0 0.00E+00 0.00E+00 - - - 4.1838 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.22030.22030.2 0.000829 26-Nov K.VPGLPTPIENMILR.Y "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1548.8698 1.36 26824 22030 2 1548.874047 775.4422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3966.9 - 3.51E+06 - - - 2.7517 - 2.254 0.379 - 300.1 1 2 0 0.0043 14 0 0 0 1.11E+07 8.19E+06 - - - 3.8784 1 230117_WJC_METTL3_WT_vs_EV_F03.22031.22031.2 0.000634 22-Dec R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 999 26825 22031 2 1328.714532 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3967 - 3.31E+06 - - - -3.1722 - 2.24 0.465 - 348.1 1 2 0 -0.0042 12 0 0 0 2.06E+07 0.00E+00 - - - 4.5961 1 230117_WJC_METTL3_WT_vs_EV_F03.22035.22035.2 8.56E-06 16/26 K.MQLMELAILNGTYR.D "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1651.8426 2.35 26829 22035 2 1651.842169 826.9286 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 5.75 3967.3 - 2.28E+06 - - - -0.2512 - 2.706 0.524 - 745.5 1 2 0 -0.0004 14 0 0 0 1.06E+07 4.53E+06 - - - 5.4092 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22036.22036.3 0.0112 Nov-52 K.MQLMELAILNGTYR.D "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1651.8426 1.76 26830 22036 3 1651.842911 551.6215 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 5.75 3967.3 - 2.18E+06 - - - 0.198 - 2.072 0.365 - 121 1 2 0 0.0003 14 0 0 0 7.81E+06 4.44E+06 - - - 4.5453 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.22039.22039.2 0.0046 16-Aug R.FLILPDMLK[136.11].N sp|P62318|SMD3_HUMAN 1 1096.6446 1.24 26832 22039 2 1096.645576 549.3296 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.84 3967.6 - 1.23E+07 - - - 0.9 - 1.601 0.38 - 175.1 1 2 0 0.001 9 0 0 0 5.42E+07 4.37E+07 - - - 3.2089 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.22041.22041.2 0.0299 16-Oct R.FLILPDMLK.N sp|P62318|SMD3_HUMAN 1 1088.6304 1.24 26834 22041 2 1088.631815 545.3225 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.84 3967.6 - 1.28E+07 - - - 1.3099 - 1.641 0.389 - 287.7 1 2 0 0.0014 9 0 0 0 5.42E+07 4.37E+07 - - - 3.3467 1 230117_WJC_METTL3_WT_vs_EV_F03.22042.22042.3 1.21E-05 Dec-52 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.31 26835 22042 3 1676.901605 559.9734 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3967.7 - 6.54E+06 - - - 1.8504 - 2.534 0.546 - 183.2 1 2 0 0.0031 14 0 0 0 2.46E+07 1.88E+07 - - - 7.0975 1 230117_WJC_METTL3_WT_vs_EV_F03.22047.22047.2 0.00109 15/24 R.DPQLVPILIEAAR.N "sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 2 1433.8242 -1 26840 22047 2 1433.820785 717.9194 "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=NSDHL PE=1 SV=2" 4.37 3968 - 1.73E+06 - - - -2.3922 - 2.505 0.529 - 580.9 1 2 0 -0.0034 13 0 0 0 0.00E+00 0.00E+00 - - - 5.3039 0.9932 230117_WJC_METTL3_WT_vs_EV_F03.22050.22050.2 0.24 12-Jun K.DVLDSVL.- sp|P81605|DCD_HUMAN 1 759.4014 - 26843 22050 2 759.401422 380.708 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.56 3968.2 - 1.50E+06 - - - -0.0171 - 1.138 0.215 - 132 1 2 0 0 7 0 0 0 - - - - - 1.0386 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.22055.22055.2 0.000392 20-Dec R.AIQDAILEVLK.E "sp|Q86Y56|DAAF5_HUMAN,tr|H0Y650|H0Y650_HUMAN,tr|E9PGY2|E9PGY2_HUMAN" 3 1211.7125 -1 26848 22055 2 1211.712667 606.8635 Dynein axonemal assembly factor 5 OS=Homo sapiens OX=9606 GN=DNAAF5 PE=1 SV=4 4.37 3968.8 - 1.14E+06 - - - 0.1056 - 2.085 0.411 - 229.4 1 2 0 0.0001 11 0 0 0 0.00E+00 0.00E+00 - - - 4.0643 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22057.22057.2 0.00405 24-Dec R.IASGLGLAWIVGR[166.11].V "sp|O14880|MGST3_HUMAN,tr|Q5VV87|Q5VV87_HUMAN,tr|Q5VV89|Q5VV89_HUMAN" 3 1321.7746 -1 26850 22057 2 1321.776926 661.8946 Microsomal glutathione S-transferase 3 OS=Homo sapiens OX=9606 GN=MGST3 PE=1 SV=1 9.75 3969 - 1.06E+06 - - - 1.7779 - 2.311 0.425 - 461.6 1 2 0 0.0024 13 0 0 0 0.00E+00 0.00E+00 - - - 4.3292 0.998 230117_WJC_METTL3_WT_vs_EV_F03.22059.22059.3 0.0183 Nov-52 K.MQLMELAILNGTYR[166.11].D "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1661.8509 1.82 26851 22059 3 1661.856103 554.9576 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 5.75 3969.3 - 239730 - - - 3.1585 - 1.922 0.255 - 81.5 1 2 0 0.0053 14 0 0 0 8.07E+06 4.44E+06 - - - 3.1179 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.22061.22061.3 0.00344 13/44 K.C[160.03]LVFSLIGLHFK[136.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1440.8043 0.87 26853 22061 3 1440.80668 481.2754 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3969.4 - 8.06E+06 - - - 1.6671 - 2.453 0.441 - 237.5 1 2 0 0.0024 12 0 0 0 1.29E+07 1.49E+07 - - - 5.9433 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.22062.22062.3 9.29E-06 16/44 K.C[160.03]LVFSLIGLHFK.L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1432.7901 0.87 26854 22062 3 1432.79217 478.604 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3969.5 - 6.91E+06 - - - 1.4601 - 2.59 0.466 - 448.8 1 2 0 0.0021 12 0 0 0 1.29E+07 1.49E+07 - - - 6.3727 1 230117_WJC_METTL3_WT_vs_EV_F03.22063.22063.3 7.02E-10 17/68 K.LLGTIYTAAEEIEAVGGK.A sp|Q6YN16|HSDL2_HUMAN 1 1833.9724 -1 26855 22063 3 1833.976096 612.3314 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3969.5 - 2.54E+06 - - - 2.018 - 3.283 0.603 - 418.6 1 2 0 0.0037 18 0 0 0 0.00E+00 0.00E+00 - - - 8.222 1 230117_WJC_METTL3_WT_vs_EV_F03.22065.22065.2 3.37E-10 18/34 K.LLGTIYTAAEEIEAVGGK.A sp|Q6YN16|HSDL2_HUMAN 1 1833.9724 -1 26857 22065 2 1833.977198 917.9935 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3969.7 - 2.11E+06 - - - 2.6189 - 3.699 0.67 - 1092 1 2 0 0.0048 18 0 0 0 0.00E+00 0.00E+00 - - - 7.204 0.9915 230117_WJC_METTL3_WT_vs_EV_F03.22066.22066.2 0.00436 20-Sep K.LVLADLLEPVK.T sp|Q9BVJ6|UT14A_HUMAN 1 1208.738 1.66 26858 22066 2 1208.746917 605.3763 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3969.7 - 2.03E+06 - - - 7.3556 - 2.005 0.471 - 166.6 1 2 0 0.0089 11 0 0 0 2.92E+07 1.76E+07 - - - 4.3989 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.22068.22068.2 4.23E-05 14-Sep R.C[160.03]FLSWLVK.L sp|Q92900|RENT1_HUMAN 1 1051.5525 -1 26860 22068 2 1051.554774 526.7835 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.22 3969.9 - 1.43E+06 - - - 2.1872 - 1.966 0.414 - 310 1 2 0 0.0023 8 0 0 0 0.00E+00 0.00E+00 - - - 4.1369 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.22069.22069.2 0.000359 22-Nov K.C[160.03]LVFSLIGLHFK[136.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1440.8043 0.29 26861 22069 2 1440.807916 721.4094 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3970 - 1.33E+06 - - - 2.525 - 1.785 0.342 - 337.5 1 2 0 0.0036 12 0 0 0 1.68E+06 5.84E+06 - - - 3.0904 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22083.22083.2 7.31E-05 18-Oct K.GGFDWNLVFK.W sp|Q10471|GALT2_HUMAN 1 1181.5869 1.29 26874 22083 2 1181.589354 591.8007 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.84 3971.7 - 3.17E+06 - - - 2.0388 - 1.828 0.458 - 209.7 1 2 0 0.0024 10 0 0 0 5.90E+06 4.58E+06 - - - 4.1068 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.22084.22084.2 0.000507 20-Oct K.LVLADLLEPVK[136.11].T sp|Q9BVJ6|UT14A_HUMAN 1 1216.7522 1.66 26875 22084 2 1216.753981 609.3834 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3971.7 - 2.34E+06 - - - 1.4424 - 1.913 0.366 - 246.3 1 2 0 0.0018 11 0 0 0 2.92E+07 1.76E+07 - - - 3.4985 0.9803 230117_WJC_METTL3_WT_vs_EV_F03.22089.22089.2 0.592 12-Jul K.NIFLLFK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 893.5375 -1 26880 22089 2 893.538628 447.776 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.75 3972.1 - 1.78E+06 - - - 1.2904 - 1.29 0.022 - 211.7 1 2 0 0.0012 7 0 0 0 0.00E+00 0.00E+00 - - - 0.01 1 230117_WJC_METTL3_WT_vs_EV_F03.22091.22091.2 4.94E-07 15/22 K.QFEELTLGEFLK.L "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1452.75 14.15 26882 22091 2 1452.752862 727.3823 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.25 3972.3 - 1.46E+06 - - - 1.9377 - 2.748 0.532 - 1034 1 2 0 0.0028 12 0 0 0 1.59E+07 1.12E+06 - - - 5.6292 1 230117_WJC_METTL3_WT_vs_EV_F03.22092.22092.2 1.53E-06 14/22 K.GDLDLELVLLC[160.03]K[136.11].E "sp|Q12906|ILF3_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 1394.7571 -1 26883 22092 2 1394.759517 698.3858 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.03 3972.4 - 1.37E+06 - - - 1.7666 - 2.856 0.533 - 743.1 1 2 0 0.0025 12 0 0 0 0.00E+00 0.00E+00 - - - 5.7382 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22093.22093.2 0.000218 24-Dec K.IPLKPPPLELLNV.- sp|O15504|NUP42_HUMAN 1 1441.8908 2.1 26884 22093 2 1441.893674 721.9527 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 3972.5 - 1.31E+06 - - - 1.9669 - 2.064 0.477 - 462.6 1 2 0 0.0028 13 0 0 0 7.84E+06 3.73E+06 - - - 4.4231 1 230117_WJC_METTL3_WT_vs_EV_F03.22099.22099.2 0.000304 15/26 K.IVQVALNGLENILR.L "sp|O60684|IMA7_HUMAN,sp|O15131|IMA6_HUMAN,sp|P52294|IMA5_HUMAN" 3 1550.9144 -1 26890 22099 2 1550.92117 776.4645 Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1 6 3973.1 - 699691 - - - 4.3478 - 3.304 0.397 - 1074.7 1 2 0 0.0067 14 0 0 0 0.00E+00 0.00E+00 - - - 4.9703 1 230117_WJC_METTL3_WT_vs_EV_F03.22104.22104.3 5.54E-09 24/80 N.WITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 2344.2539 7.08 26894 22104 3 2344.257957 782.4253 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3973.5 - 5.65E+06 - - - 1.7178 - 3.823 0.658 - 450.4 1 1 0 0.004 21 0 0 0 3.61E+07 5.09E+06 - - - 9.09 1 230117_WJC_METTL3_WT_vs_EV_F03.22105.22105.2 0.000262 16-Oct R.VNILFDFVK.K sp|P55010|IF5_HUMAN 1 1093.6172 -1 26895 22105 2 1093.619542 547.8159 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.81 3973.6 - 5.27E+06 - - - 2.158 - 2.157 0.48 - 447 1 2 0 0.0024 9 0 0 0 0.00E+00 0.00E+00 - - - 4.8095 1 230117_WJC_METTL3_WT_vs_EV_F03.22106.22106.2 0.00278 13/18 K.STLLLLLTGK[136.11].L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1065.6889 -1 26896 22106 2 1065.689839 533.8517 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3973.6 - 5.21E+06 - - - 0.8839 - 2.386 0.436 - 635.1 1 2 0 0.0009 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6884 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.22107.22107.2 0.0805 16-Sep R.VNILFDFVK[136.11].K sp|P55010|IF5_HUMAN 1 1101.6314 -1 26897 22107 2 1101.632512 551.823 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.81 3973.6 - 4.63E+06 - - - 1.0258 - 2.043 0.337 - 327.8 1 2 0 0.0011 9 0 0 0 0.00E+00 0.00E+00 - - - 3.5966 1 230117_WJC_METTL3_WT_vs_EV_F03.22108.22108.2 6.02E-05 18-Oct K.STLLLLLTGK.L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1057.6747 1.06 26898 22108 2 1057.6764 529.8446 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3973.7 - 4.11E+06 - - - 1.6101 - 2.025 0.592 - 342.7 1 2 0 0.0017 10 0 0 0 1.39E+07 1.31E+07 - - - 5.3824 0.9827 230117_WJC_METTL3_WT_vs_EV_F03.22113.22113.2 0.0144 14-Aug R.GFGFILFK[136.11].D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 935.536 0.87 26903 22113 2 935.534255 468.7753 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3974 - 2.53E+06 - - - -1.892 - 1.351 0.172 - 209.5 1 2 0 -0.0018 8 0 0 0 6.54E+07 7.56E+07 - - - 1.2182 1 230117_WJC_METTL3_WT_vs_EV_F03.22114.22114.3 0.000546 16/52 K.FLTLPPVLHLQLMR.F "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1676.98 2.07 26904 22114 3 1676.981818 560.0006 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 9.76 3974 - 2.02E+06 - - - 1.0817 - 2.621 0.49 - 366.2 1 2 0 0.0018 14 0 0 0 9.68E+06 4.68E+06 - - - 6.5632 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.22115.22115.2 3.54E-05 26-Sep R.VLDVNLMGTFNVIR[166.11].L "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 1599.8682 -1 26905 22115 2 1599.872498 800.9414 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 5.81 3974.1 - 1.96E+06 - - - 2.6752 - 2.048 0.437 - 269.2 1 2 0 0.0043 14 0 0 0 0.00E+00 0.00E+00 - - - 4.0663 1 230117_WJC_METTL3_WT_vs_EV_F03.22116.22116.2 3.67E-05 14/24 R.LLSLISIALPENK.V "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1409.8494 2.88 26906 22116 2 1409.852245 705.932 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 6 3974.1 - 1.78E+06 - - - 2.0414 - 2.816 0.559 - 647 1 2 0 0.0029 13 0 0 0 8.08E+06 2.80E+06 - - - 5.826 1 230117_WJC_METTL3_WT_vs_EV_F03.22117.22117.3 0.000109 14/52 K.FLTLPPVLHLQLMR[166.11].F "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1686.9883 2.16 26907 22117 3 1686.99159 563.3367 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 9.76 3974.2 - 1.60E+06 - - - 1.9656 - 2.56 0.493 - 195.4 1 2 0 0.0033 14 0 0 0 9.68E+06 4.48E+06 - - - 6.5336 0.9985 230117_WJC_METTL3_WT_vs_EV_F03.22118.22118.2 0.197 24-Sep K.IPLK[136.11]PPPLELLNV.- sp|O15504|NUP42_HUMAN 1 1449.905 2.1 26908 22118 2 1449.907117 725.9598 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 3974.3 - 1.46E+06 - - - 1.4339 - 1.306 0.307 - 141 1 2 0 0.0021 13 0 0 0 7.84E+06 3.73E+06 - - - 1.993 0.9968 230117_WJC_METTL3_WT_vs_EV_F03.22119.22119.2 0.316 14-Aug K.GSLLDFLK.E "sp|P07947|YES_HUMAN,sp|P09769|FGR_HUMAN,sp|P07948|LYN_HUMAN,sp|P08631|HCK_HUMAN,sp|P06241|FYN_HUMAN,sp|P12931|SRC_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|J3QRU1|J3QRU1_HUMAN" 9 891.5066 3.64 26909 22119 2 891.507402 446.7606 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 3974.4 - 1.37E+06 - - - 0.9344 - 1.477 0.155 - 213.5 1 2 0 0.0008 8 0 0 0 7.87E+06 2.16E+06 - - - 1.3618 1 230117_WJC_METTL3_WT_vs_EV_F03.22122.22122.3 1.00E-08 18/60 R.LLLLLGAAAAAASQTR.G sp|Q12849|GRSF1_HUMAN 1 1538.9144 -1 26911 22122 3 1538.915214 513.9788 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 9.75 3974.7 - 956429 - - - 0.5114 - 3.041 0.6 - 439 1 2 0 0.0008 16 0 0 0 0.00E+00 0.00E+00 - - - 8.0829 0.9942 230117_WJC_METTL3_WT_vs_EV_F03.22124.22124.2 0.046 14-Jun R.GFGFILFK.D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 927.5218 0.87 26913 22124 2 927.521962 464.7682 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3974.8 - 1.58E+07 - - - 0.1477 - 1.187 0.209 - 106.2 1 2 0 0.0001 8 0 0 0 6.54E+07 7.56E+07 - - - 1.1017 1 230117_WJC_METTL3_WT_vs_EV_F03.22126.22126.2 1.78E-05 18-Oct K.ILYDILAFAK.E "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1165.6747 -1 26915 22126 2 1165.67515 583.8446 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.83 3974.9 - 6.71E+06 - - - 0.3886 - 2.184 0.469 - 241 1 2 0 0.0005 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6853 1 230117_WJC_METTL3_WT_vs_EV_F03.22127.22127.2 1.06E-05 18-Dec K.ILYDILAFAK[136.11].E "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1173.6889 -1 26916 22127 2 1173.691766 587.8517 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.83 3975 - 5.46E+06 - - - 2.4444 - 2.449 0.501 - 324.2 1 2 0 0.0029 10 0 0 0 0.00E+00 0.00E+00 - - - 5.2406 1 230117_WJC_METTL3_WT_vs_EV_F03.22128.22128.2 5.08E-05 20-Oct R.LWGLTEMFPER.V sp|Q9NS69|TOM22_HUMAN 1 1377.6751 1.36 26917 22128 2 1377.674413 689.8448 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 4.53 3975 - 4.03E+06 - - - -0.5045 - 2.206 0.515 - 363.9 1 2 0 -0.0007 11 0 0 0 1.26E+07 9.22E+06 - - - 4.9849 1 230117_WJC_METTL3_WT_vs_EV_F03.22132.22132.2 2.73E-07 13/22 R.LGDPLEAFPVFK[136.11].K "sp|Q86UY6|NAA40_HUMAN,tr|F5H2C9|F5H2C9_HUMAN" 2 1339.7267 1.23 26921 22132 2 1339.724831 670.8706 N-alpha-acetyltransferase 40 OS=Homo sapiens OX=9606 GN=NAA40 PE=1 SV=1 4.37 3975.2 - 2.83E+06 - - - -1.4242 - 2.575 0.581 - 701.8 1 2 0 -0.0019 12 0 0 0 1.31E+07 1.06E+07 - - - 5.8204 0.9826 230117_WJC_METTL3_WT_vs_EV_F03.22137.22137.2 0.439 24-Sep R.VSELQVLLGYAGR.N "sp|O75925|PIAS1_HUMAN,tr|H3BSI8|H3BSI8_HUMAN" 2 1403.7773 -1 26926 22137 2 1403.78139 702.8959 E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=9606 GN=PIAS1 PE=1 SV=2 5.97 3975.7 - 1.33E+06 - - - 2.9385 - 1.457 0.082 - 170 2 2 0 0.0041 13 0 0 0 0.00E+00 0.00E+00 - - - 0.4769 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.22138.22138.3 0.00033 Aug-44 K.LIQLMEEIMAEK.E "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1446.7462 -1 26927 22138 3 1446.745229 483.256 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.25 3975.8 - 1.25E+06 - - - -0.6878 - 1.987 0.366 - 121.2 1 2 0 -0.001 12 0 0 0 0.00E+00 0.00E+00 - - - 4.5235 1 230117_WJC_METTL3_WT_vs_EV_F03.22142.22142.2 1.47E-07 17/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 5.52 26930 22142 2 1591.943355 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3976.4 - 4.81E+06 - - - -1.0327 - 2.945 0.629 - 668.2 1 2 0 -0.0016 15 0 0 0 5.09E+07 9.21E+06 - - - 6.3418 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.22148.22148.2 0.0268 18-Jul K.FLLFSSLVTK.E "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V686|A0A7I2V686_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 1153.6747 -1 26935 22148 2 1153.675867 577.8446 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 8.75 3976.7 - 5.51E+06 - - - 1.0142 - 1.468 0.387 - 117.1 1 2 0 0.0012 10 0 0 0 0.00E+00 0.00E+00 - - - 2.9706 1 230117_WJC_METTL3_WT_vs_EV_F03.22149.22149.2 5.60E-07 18-Oct R.DFVVGALILR.S sp|Q9NUD5|ZCHC3_HUMAN 1 1101.6546 -1 26936 22149 2 1101.656477 551.8346 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 5.84 3976.8 - 3.33E+06 - - - 1.6766 - 1.845 0.545 - 433.3 1 2 0 0.0018 10 0 0 0 0.00E+00 0.00E+00 - - - 4.7754 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.22150.22150.2 1.37 18-Nov R.ILGLLDAYLK[136.11].T sp|P26641|EF1G_HUMAN 1 1125.6889 0.88 26937 22150 2 1125.690883 563.8517 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3976.9 - 2.53E+06 - - - 1.7643 - 2.247 0.282 - 260.9 1 2 0 0.002 10 0 0 0 4.60E+07 5.25E+07 - - - 3.3831 1 230117_WJC_METTL3_WT_vs_EV_F03.22151.22151.2 1.89E-05 18-Sep R.DFVVGALILR[166.11].S sp|Q9NUD5|ZCHC3_HUMAN 1 1111.6629 1.45 26938 22151 2 1111.664582 556.8387 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 5.84 3976.9 - 2.51E+06 - - - 1.513 - 2.017 0.529 - 347.4 1 2 0 0.0017 10 0 0 0 9.69E+06 6.67E+06 - - - 4.9061 0.9989 230117_WJC_METTL3_WT_vs_EV_F03.22152.22152.2 0.000443 16-Aug K.EVWDYVFFK[136.11].E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PRP1|A0A6I8PRP1_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 1239.6056 -1 26939 22152 2 1239.603655 620.8101 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.37 3977 - 1.76E+06 - - - -1.5376 - 1.713 0.5 - 252.5 1 2 0 -0.0019 9 0 0 0 0.00E+00 0.00E+00 - - - 4.2906 1 230117_WJC_METTL3_WT_vs_EV_F03.22153.22153.2 4.66E-08 13/20 K.TFSFAIPLIER[166.11].L sp|Q9BQ39|DDX50_HUMAN 1 1302.7211 -1 26940 22153 2 1302.725705 652.3678 ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1 5.66 3977.1 - 1.69E+06 - - - 3.5019 - 2.159 0.562 - 531.4 1 2 0 0.0046 11 0 0 0 0.00E+00 0.00E+00 - - - 5.2726 1 230117_WJC_METTL3_WT_vs_EV_F03.22154.22154.2 5.25E-11 21/30 K.LPIVNEDDELVAIIAR.T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1778.9778 1.84 26941 22154 2 1778.979234 890.4962 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3977.2 - 1.61E+06 - - - 0.7976 - 3.966 0.673 - 1291.9 1 2 0 0.0014 16 0 0 0 1.25E+07 6.77E+06 - - - 7.3986 1 230117_WJC_METTL3_WT_vs_EV_F03.22156.22156.2 0.00161 26-Dec R.GLLEESSFATLFPK[136.11].Y sp|Q13601|KRR1_HUMAN 1 1545.817 0.98 26943 22156 2 1545.817299 773.9158 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3977.3 - 1.40E+06 - - - 0.1863 - 2.559 0.57 - 412.3 1 2 0 0.0003 14 0 0 0 8.98E+06 9.12E+06 - - - 5.6088 1 230117_WJC_METTL3_WT_vs_EV_F03.22158.22158.2 6.90E-08 13/20 K.TFSFAIPLIER.L sp|Q9BQ39|DDX50_HUMAN 1 1292.7129 -1 26945 22158 2 1292.715038 647.3637 ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1 5.66 3977.5 - 1.32E+06 - - - 1.6748 - 2.27 0.49 - 522.5 1 2 0 0.0022 11 0 0 0 0.00E+00 0.00E+00 - - - 4.8772 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.22160.22160.2 0.00435 14-Aug R.SIFLFLDR.T "sp|Q13619|CUL4A_HUMAN,sp|Q13620|CUL4B_HUMAN,tr|A0A7P0Z4G9|A0A7P0Z4G9_HUMAN,tr|A0A7P0T8P8|A0A7P0T8P8_HUMAN,tr|A0A7P0T9D0|A0A7P0T9D0_HUMAN,tr|A0A669KAX4|A0A669KAX4_HUMAN,tr|A0A0A0MR50|A0A0A0MR50_HUMAN,tr|K4DI93|K4DI93_HUMAN,tr|A0A804CL36|A0A804CL36_HUMAN,tr|A0A7P0T9C8|A0A7P0T9C8_HUMAN,tr|A0A7P0T954|A0A7P0T954_HUMAN,tr|A0A087WWN2|A0A087WWN2_HUMAN,tr|A0A7P0T9P5|A0A7P0T9P5_HUMAN,tr|A0A669KBG9|A0A669KBG9_HUMAN,tr|A0A7P0T9R8|A0A7P0T9R8_HUMAN,tr|A0A7P0TAF9|A0A7P0TAF9_HUMAN,tr|A0A7P0T9L3|A0A7P0T9L3_HUMAN,tr|A0A7P0TAQ3|A0A7P0TAQ3_HUMAN" 18 1009.5597 1.76 26947 22160 2 1009.56181 505.7871 Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV=3 5.55 3977.7 - 1.27E+06 - - - 2.1227 - 1.692 0.337 - 282.2 1 2 0 0.0021 8 0 0 0 9.18E+06 5.23E+06 - - - 3.1155 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.22165.22165.3 1.51E-05 16/56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 6.64 26951 22165 3 1591.947155 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3978.3 - 1.97E+06 - - - 1.3543 - 2.626 0.47 - 260.1 1 2 0 0.0022 15 0 0 0 1.69E+07 2.55E+06 - - - 6.2987 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.22167.22167.2 0.000463 18-Dec R.ILGLLDAYLK.T sp|P26641|EF1G_HUMAN 1 1117.6747 0.88 26953 22167 2 1117.677585 559.8446 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3978.5 - 2.04E+07 - - - 2.5839 - 2.391 0.321 - 363.5 1 2 0 0.0029 10 0 0 0 4.60E+07 5.25E+07 - - - 3.8442 1 230117_WJC_METTL3_WT_vs_EV_F03.22169.22169.2 2.12E-09 20/30 K.LPIVNEDDELVAIIAR[166.11].T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1788.9861 1.84 26955 22169 2 1788.987673 895.5003 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3978.6 - 1.83E+06 - - - 0.8877 - 3.844 0.688 - 1188.9 1 2 0 0.0016 16 0 0 0 1.25E+07 6.77E+06 - - - 7.4325 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22171.22171.2 0.000549 22-Oct K.VNFLPEIITLSK[136.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1380.8108 0.72 26957 22171 2 1380.813437 691.4127 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.97 3978.8 - 1.29E+06 - - - 1.9076 - 1.948 0.437 - 264.3 1 2 0 0.0026 12 0 0 0 8.78E+06 1.22E+07 - - - 4.0223 1 230117_WJC_METTL3_WT_vs_EV_F03.22173.22173.2 0.00672 14/24 R.SDFFLEGPFMPPR.M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1538.7228 2.02 26959 22173 2 1538.724516 770.3687 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3979.1 - 998685 - - - 1.1243 - 2.663 0.522 - 618.2 1 2 0 0.0017 13 0 0 0 1.13E+07 5.57E+06 - - - 5.4097 1 230117_WJC_METTL3_WT_vs_EV_F03.22174.22174.2 3.46E-07 14/26 K.LLSDFLDSEVSELR[166.11].T sp|Q9BPX3|CND3_HUMAN 1 1631.8282 -1 26960 22174 2 1631.831813 816.9214 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 3.92 3979.2 - 966879 - - - 2.222 - 2.802 0.575 - 618.7 1 2 0 0.0036 14 0 0 0 0.00E+00 0.00E+00 - - - 5.8724 1 230117_WJC_METTL3_WT_vs_EV_F03.22175.22175.2 3.23E-06 13/22 K.VNFLPEIITLSK.E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1372.7966 -1 26961 22175 2 1372.808784 687.4056 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.97 3979.2 - 861421 - - - 8.8731 - 2.171 0.519 - 485.6 1 2 0 0.0122 12 0 0 0 0.00E+00 0.00E+00 - - - 4.9102 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22177.22177.2 0.123 16-Oct R.VPLILNLIR.H sp|Q15648|MED1_HUMAN 1 1049.6961 2.32 26963 22177 2 1049.69775 525.8553 Mediator of RNA polymerase II transcription subunit 1 OS=Homo sapiens OX=9606 GN=MED1 PE=1 SV=4 9.72 3979.4 - 552216 - - - 1.5709 - 2.152 0.348 - 320.7 1 2 0 0.0016 9 0 0 0 1.53E+06 6.58E+05 - - - 3.828 0.8904 230117_WJC_METTL3_WT_vs_EV_F03.22178.22178.2 0.122 18-Jun R.LFFPVIYDVK.Y "sp|Q9UIV1|CNOT7_HUMAN,tr|H0YBT3|H0YBT3_HUMAN,tr|H0YAV9|H0YAV9_HUMAN" 3 1239.6903 -1 26964 22178 2 1239.698195 620.8524 CCR4-NOT transcription complex subunit 7 OS=Homo sapiens OX=9606 GN=CNOT7 PE=1 SV=3 5.83 3979.6 - 538072 - - - 6.3306 - 1.112 0.187 - 69.1 1 2 0 0.0078 10 0 0 0 0.00E+00 0.00E+00 - - - 0.716 1 230117_WJC_METTL3_WT_vs_EV_F03.22182.22182.2 1.41E-05 22-Dec K.LWEMDNMLIQIK.T "sp|Q96HT8|MR1L1_HUMAN,sp|Q9Y605|MOFA1_HUMAN,tr|A0A087WTY9|A0A087WTY9_HUMAN" 3 1532.7731 -1 26968 22182 2 1532.771401 767.3938 MORF4 family-associated protein 1-like 1 OS=Homo sapiens OX=9606 GN=MRFAP1L1 PE=1 SV=1 4.37 3980.1 - 468043 - - - -1.113 - 2.264 0.478 - 392.1 1 2 0 -0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 4.721 0.9863 230117_WJC_METTL3_WT_vs_EV_F03.22184.22184.2 0.149 24-Jun R.EYMSPDIALLYLK.H sp|Q7RTY7|OVCH1_HUMAN 1 1554.8004 4.2 26970 22184 2 1554.805462 778.4075 Ovochymase-1 OS=Homo sapiens OX=9606 GN=OVCH1 PE=2 SV=2 4.37 3980.4 - 427246 - - - 3.2763 - 1.309 0.163 - 73.5 2 2 0 0.0051 13 0 0 0 4.89E+06 1.16E+06 - - - 0.7999 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.22187.22187.2 6.00E-06 18-Nov K.NIFAILQSVK.A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1131.6652 1.72 26972 22187 2 1131.667391 566.8399 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3980.7 - 8.24E+06 - - - 1.9405 - 2.2 0.352 - 323.1 1 2 0 0.0022 10 0 0 0 2.74E+07 1.59E+07 - - - 3.841 1 230117_WJC_METTL3_WT_vs_EV_F03.22190.22190.2 0.000198 14/22 R.LGPLLDILADSR.H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1281.7293 1.49 26975 22190 2 1281.732928 641.8719 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3980.8 - 5.92E+06 - - - 2.868 - 2.711 0.52 - 824.6 1 2 0 0.0037 12 0 0 0 3.39E+07 2.28E+07 - - - 5.5047 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.22191.22191.2 0.7 18-Oct K.NIFAILQSVK[136.11].A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1139.6794 1.71 26976 22191 2 1139.681758 570.847 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3980.8 - 4.60E+06 - - - 2.0734 - 2.074 0.327 - 231 1 2 0 0.0024 10 0 0 0 2.74E+07 1.60E+07 - - - 3.4917 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.22192.22192.3 2.32E-06 15/44 K.LR[166.11]EC[160.03]LPLIIFLR[166.11].N sp|P62701|RS4X_HUMAN 1 1561.9281 0.87 26977 22192 3 1561.930961 521.65 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3980.9 - 3.79E+06 - - - 1.8125 - 3.083 0.524 - 495.3 1 2 1 0.0028 12 0 0 0 4.74E+07 5.41E+07 - - - 7.5021 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.22193.22193.3 1.77E-07 18/44 K.LREC[160.03]LPLIIFLR.N sp|P62701|RS4X_HUMAN 1 1541.9116 0.87 26978 22193 3 1541.914211 514.9778 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3980.9 - 3.19E+06 - - - 1.6998 - 3.38 0.473 - 693.5 1 2 1 0.0026 12 0 0 0 4.74E+07 5.41E+07 - - - 7.1885 1 230117_WJC_METTL3_WT_vs_EV_F03.22194.22194.3 2.84E-05 14/60 K.LPIVNEDDELVAIIAR.T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1778.9778 1.6 26979 22194 3 1778.981548 593.9999 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3981 - 3.01E+06 - - - 2.0984 - 2.911 0.52 - 244 1 2 0 0.0037 16 0 0 0 1.36E+07 8.48E+06 - - - 7.0781 1 230117_WJC_METTL3_WT_vs_EV_F03.22196.22196.2 4.39E-06 13/24 R.GNSIIMLEALERV.- "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1443.7756 -1 26981 22196 2 1443.777649 722.8951 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3981.2 - 1.62E+06 - - - 1.4538 - 2.645 0.482 - 581.1 1 2 0 0.0021 13 0 0 0 0.00E+00 0.00E+00 - - - 5.0968 0.9736 230117_WJC_METTL3_WT_vs_EV_F03.22199.22199.2 0.0133 14-Aug R.EC[160.03]LNLWGY.E sp|Q86U44|MTA70_HUMAN 1 1053.459 - 26984 22199 2 1053.460632 527.7368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3981.4 - 1.37E+06 - - - 1.5805 - 1.651 0.449 - 249.1 1 1 0 0.0017 8 0 0 0 - - - - - 3.8689 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.22200.22200.3 7.00E-05 Nov-44 R.LFVWEILHSTIR[166.11].K "sp|Q09161|NCBP1_HUMAN,tr|X6R941|X6R941_HUMAN" 2 1522.8536 1.97 26985 22200 3 1522.857048 508.6251 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 6.75 3981.5 - 1.31E+06 - - - 2.2937 - 2.385 0.36 - 128.6 1 2 0 0.0035 12 0 0 0 5.26E+06 2.67E+06 - - - 4.962 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.22202.22202.3 0.00226 Dec-60 K.LPIVNEDDELVAIIAR[166.11].T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1788.9861 1.59 26987 22202 3 1788.991031 597.336 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3981.7 - 1.28E+06 - - - 2.7647 - 2.184 0.332 - 219.3 1 2 0 0.0049 16 0 0 0 1.37E+07 8.65E+06 - - - 4.2444 1 230117_WJC_METTL3_WT_vs_EV_F03.22203.22203.2 7.77E-07 14/24 R.GNSIIMLEALER[166.11]V.- "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1453.7838 -1 26988 22203 2 1453.787247 727.8992 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3981.8 - 1.24E+06 - - - 2.3573 - 2.889 0.546 - 785.8 1 2 0 0.0034 13 0 0 0 0.00E+00 0.00E+00 - - - 5.7955 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.22204.22204.2 0.274 14/22 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 1.01 26989 22204 2 1336.848811 669.4314 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3981.9 - 1.19E+06 - - - 0.4234 - 2.48 0.368 - 694.9 1 2 0 0.0006 12 0 0 0 1.18E+08 1.17E+08 - - - 4.1487 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.22205.22205.2 0.751 14/22 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 1.01 26990 22205 2 1344.865226 673.4385 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3982.1 - 1.18E+06 - - - 2.0679 - 2.56 0.343 - 681.5 1 2 0 0.0028 12 0 0 0 1.18E+08 1.17E+08 - - - 4.0468 1 230117_WJC_METTL3_WT_vs_EV_F03.22208.22208.2 1.55E-05 24-Dec R.SDFFLEGPFMPPR[166.11].M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1548.7311 2.02 26992 22208 2 1548.73461 775.3728 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3982.4 - 1.19E+06 - - - 2.2948 - 2.48 0.541 - 409 1 2 0 0.0036 13 0 0 0 1.13E+07 5.57E+06 - - - 5.3668 1 230117_WJC_METTL3_WT_vs_EV_F03.22209.22209.2 1.31E-09 18/30 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 2.66 26993 22209 2 1751.869429 876.9399 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3982.5 - 6.44E+06 - - - 2.4408 - 3.666 0.63 - 881.6 1 2 0 0.0043 16 0 0 0 3.24E+07 1.22E+07 - - - 6.8867 1 230117_WJC_METTL3_WT_vs_EV_F03.22210.22210.3 6.50E-08 15/60 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 2.41 26994 22210 3 1751.868694 584.9623 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3982.5 - 3.60E+06 - - - 2.0213 - 2.974 0.602 - 391.4 1 2 0 0.0035 16 0 0 0 1.59E+07 6.60E+06 - - - 8.0473 1 230117_WJC_METTL3_WT_vs_EV_F03.22211.22211.2 4.10E-10 16/30 K.VGEVTYVELLMDAEGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1759.8794 -1 26995 22211 2 1759.881267 880.947 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3982.6 - 2.66E+06 - - - 1.0876 - 3.257 0.646 - 571.2 1 2 0 0.0019 16 0 0 0 0.00E+00 0.00E+00 - - - 6.7148 1 230117_WJC_METTL3_WT_vs_EV_F03.22212.22212.2 1.11E-05 22-Dec K.LR[166.11]EC[160.03]LPLIIFLR[166.11].N sp|P62701|RS4X_HUMAN 1 1561.9281 0.83 26996 22212 2 1561.92963 781.9713 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3982.7 - 2.34E+06 - - - 0.9604 - 2.501 0.492 - 137.7 1 2 1 0.0015 12 0 0 0 4.85E+06 5.86E+06 - - - 5.0864 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.22214.22214.2 0.00043 16-Oct R.QLYLPMLFK.V "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN" 13 1151.6413 -1 26998 22214 2 1151.643118 576.8279 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3982.9 - 1.66E+06 - - - 1.589 - 1.739 0.311 - 284.6 1 2 0 0.0018 9 0 0 0 0.00E+00 0.00E+00 - - - 2.9382 0.9981 230117_WJC_METTL3_WT_vs_EV_F03.22215.22215.2 0.00787 18-Jul K.GGPGLPLPPL.- sp|Q9H7N4|SFR19_HUMAN 1 916.5382 - 26999 22215 2 916.539565 459.2764 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.52 3982.9 - 1.52E+06 - - - 1.486 - 1.34 0.258 - 174.5 1 2 0 0.0014 10 0 0 0 - - - - - 1.7631 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22217.22217.2 0.000341 22-Oct R.VLGLLGALDPYK.H sp|P42345|MTOR_HUMAN 1 1257.7333 1.3 27001 22217 2 1257.734481 629.8739 Serine\threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 5.81 3983.1 - 1.29E+06 - - - 0.9589 - 2.039 0.446 - 259.4 1 2 0 0.0012 12 0 0 0 5.49E+06 4.23E+06 - - - 4.2094 1 230117_WJC_METTL3_WT_vs_EV_F03.22218.22218.3 3.00E-09 14/60 K.VGEVTYVELLMDAEGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1759.8794 2.41 27002 22218 3 1759.880676 587.6337 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3983.2 - 1.27E+06 - - - 0.7518 - 2.893 0.587 - 265.5 1 2 0 0.0013 16 0 0 0 1.59E+07 6.60E+06 - - - 7.8098 1 230117_WJC_METTL3_WT_vs_EV_F03.22219.22219.2 0.000836 28-Nov R.SILNADVAELLVVEK.D sp|Q8WVM0|TFB1M_HUMAN 1 1611.9083 -1 27003 22219 2 1611.908585 806.9614 "Dimethyladenosine transferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=TFB1M PE=1 SV=1" 4.14 3983.3 - 1.24E+06 - - - 0.1532 - 2.501 0.47 - 261 1 2 0 0.0002 15 0 0 0 0.00E+00 0.00E+00 - - - 4.7661 0.9018 230117_WJC_METTL3_WT_vs_EV_F03.22220.22220.2 0.0204 12-Jun K.TSFFQAL.G "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 9 812.4069 - 27004 22220 2 812.407622 407.2107 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 5.19 3983.4 - 1.17E+06 - - - 0.9441 - 1.209 0.333 - 135 1 1 0 0.0008 7 0 0 0 - - - - - 2.1017 0.9926 230117_WJC_METTL3_WT_vs_EV_F03.22225.22225.2 0.531 28-Aug R.SILNADVAELLVVEK[136.11].D sp|Q8WVM0|TFB1M_HUMAN 1 1619.9225 -1 27009 22225 2 1619.927055 810.9685 "Dimethyladenosine transferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=TFB1M PE=1 SV=1" 4.14 3984 - 728900 - - - 2.7884 - 1.436 0.151 - 85.3 1 2 0 0.0045 15 0 0 0 0.00E+00 0.00E+00 - - - 1.0445 1 230117_WJC_METTL3_WT_vs_EV_F03.22228.22228.2 0.00256 14/18 K.LASDLLEWIR.R "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|G3V2W4|G3V2W4_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 14 1214.6659 1.23 27011 22228 2 1214.666959 608.3402 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.37 3984.4 - 6.00E+06 - - - 0.8529 - 2.683 0.431 - 775.7 1 2 0 0.001 10 0 0 0 1.05E+07 8.48E+06 - - - 4.9789 1 230117_WJC_METTL3_WT_vs_EV_F03.22230.22230.2 0.000144 22-Nov R.YLDFSSIITEVR.A sp|Q8N1N4|K2C78_HUMAN 1 1441.7453 -1 27013 22230 2 1441.748688 721.8799 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.37 3984.6 - 4.20E+06 - - - 2.3527 - 2.412 0.562 - 356.5 1 2 0 0.0034 12 0 0 0 0.00E+00 0.00E+00 - - - 5.5075 1 230117_WJC_METTL3_WT_vs_EV_F03.22231.22231.2 3.38E-06 14/28 K.LGLLGLANSLAIEGR.K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1495.8722 -1 27014 22231 2 1495.876278 748.9434 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3984.6 - 3.59E+06 - - - 2.7075 - 2.863 0.569 - 707.5 1 2 0 0.004 15 0 0 0 0.00E+00 0.00E+00 - - - 5.8284 1 230117_WJC_METTL3_WT_vs_EV_F03.22232.22232.2 1.49E-06 14/20 K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 -1 27015 22232 2 1315.788955 658.9005 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3984.7 - 3.36E+06 - - - 1.9623 - 2.269 0.568 - 721.6 1 2 0 0.0026 11 0 0 0 0.00E+00 0.00E+00 - - - 5.4519 1 230117_WJC_METTL3_WT_vs_EV_F03.22233.22233.3 2.12E-05 15/44 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 1.09 27016 22233 3 1336.849807 446.6234 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3984.7 - 3.05E+06 - - - 1.1684 - 2.497 0.518 - 306.3 1 2 0 0.0016 12 0 0 0 9.83E+06 9.02E+06 - - - 6.8512 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.22234.22234.3 2.12E-05 14/44 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 1.09 27017 22234 3 1344.864344 449.2948 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3984.8 - 3.04E+06 - - - 1.412 - 2.366 0.47 - 270.3 1 2 0 0.0019 12 0 0 0 9.83E+06 9.02E+06 - - - 6.1666 1 230117_WJC_METTL3_WT_vs_EV_F03.22235.22235.2 5.20E-05 14/22 K.SVEELLEAELLK[136.11].V "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 1379.7639 1.46 27018 22235 2 1379.766738 690.8892 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.09 3984.8 - 2.65E+06 - - - 2.0475 - 2.659 0.477 - 563.6 1 2 0 0.0028 12 0 0 0 6.94E+06 4.77E+06 - - - 5.1364 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.22236.22236.2 1.72E-05 18-Oct K.VLVYELLLGK.G sp|Q96P11|NSUN5_HUMAN 1 1145.706 -1 27019 22236 2 1145.708577 573.8603 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 5.97 3984.9 - 2.60E+06 - - - 2.2519 - 1.952 0.42 - 298.8 1 2 0 0.0026 10 0 0 0 0.00E+00 0.00E+00 - - - 4.0093 0.9924 230117_WJC_METTL3_WT_vs_EV_F03.22238.22238.2 0.0364 18-Oct K.VLVYELLLGK[136.11].G sp|Q96P11|NSUN5_HUMAN 1 1153.7202 -1 27021 22238 2 1153.725378 577.8674 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 5.97 3985 - 2.25E+06 - - - 4.4907 - 1.574 0.223 - 192.1 1 2 0 0.0052 10 0 0 0 0.00E+00 0.00E+00 - - - 1.9526 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.22239.22239.3 0.0452 Nov-56 K.LGLLGLANSLAIEGR.K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1495.8722 -1 27022 22239 3 1495.874773 499.6314 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3985.1 - 2.04E+06 - - - 1.7013 - 1.484 0.292 - 155.9 1 2 0 0.0025 15 0 0 0 0.00E+00 0.00E+00 - - - 2.8248 1 230117_WJC_METTL3_WT_vs_EV_F03.22240.22240.2 5.05E-07 14/28 K.LGLLGLANSLAIEGR[166.11].K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1505.8805 -1 27023 22240 2 1505.883452 753.9475 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3985.1 - 1.76E+06 - - - 1.9616 - 2.856 0.559 - 787.5 1 2 0 0.003 15 0 0 0 0.00E+00 0.00E+00 - - - 5.7489 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22241.22241.3 0.0025 Nov-44 K.SVEELLEAELLK.V "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 1371.7497 2.2 27024 22241 3 1371.751272 458.2572 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.09 3985.2 - 1.70E+06 - - - 1.1365 - 2.011 0.328 - 216.7 1 2 0 0.0016 12 0 0 0 2.81E+06 1.28E+06 - - - 4.1329 1 230117_WJC_METTL3_WT_vs_EV_F03.22242.22242.2 4.51E-07 28-Dec R.YLPDTLLLEEC[160.03]GLLR.K "sp|P21964|COMT_HUMAN,tr|E7EMS6|E7EMS6_HUMAN" 2 1803.9441 -1 27025 22242 2 1803.953025 902.9793 Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT PE=1 SV=2 4.14 3985.4 - 958376 - - - 4.963 - 2.437 0.528 - 451 1 2 0 0.009 15 0 0 0 0.00E+00 0.00E+00 - - - 5.128 0.9921 230117_WJC_METTL3_WT_vs_EV_F03.22243.22243.3 0.345 Jul-44 R.YLDFSSIITEVR.A sp|Q8N1N4|K2C78_HUMAN 1 1441.7453 -1 27026 22243 3 1441.747737 481.589 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.37 3985.5 - 894594 - - - 1.6931 - 1.549 0.172 - 73 1 2 0 0.0024 12 0 0 0 0.00E+00 0.00E+00 - - - 1.6699 0.9931 230117_WJC_METTL3_WT_vs_EV_F03.22244.22244.3 0.123 Sep-44 K.SVEELLEAELLK[136.11].V "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 1379.7639 -1 27027 22244 3 1379.766386 460.9286 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.09 3985.6 - 892209 - - - 1.7923 - 1.52 0.185 - 114.2 1 2 0 0.0025 12 0 0 0 0.00E+00 0.00E+00 - - - 1.7625 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22245.22245.2 4.15E-06 26-Dec R.LLQSPC[160.03]PFC[160.03]DSPVF.- sp|Q9UKN8|TF3C4_HUMAN 1 1665.7531 - 27028 22245 2 1665.755428 833.8838 General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2 3.8 3985.7 - 848633 - - - 1.397 - 1.853 0.52 - 326.4 1 2 0 0.0023 14 0 0 0 - - - - - 4.4288 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22246.22246.2 0.00416 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 27029 22246 2 1603.766214 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3985.9 - 788285 - - - 1.4179 - 1.921 0.446 - 243.8 1 2 0 0.0023 12 0 0 0 7.11E+06 0.00E+00 - - - 4.0522 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.22247.22247.3 0.00251 Dec-40 K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 -1 27030 22247 3 1315.788741 439.6027 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3986 - 730555 - - - 1.7997 - 2.245 0.417 - 211.4 1 2 0 0.0024 11 0 0 0 0.00E+00 0.00E+00 - - - 5.4859 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.22249.22249.2 0.0147 13/22 R.LGPLLDILADSR[166.11].H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1291.7375 1.49 27031 22249 2 1291.741103 646.876 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3986.3 - 613113 - - - 2.7722 - 2.298 0.415 - 630.1 1 2 0 0.0036 12 0 0 0 3.39E+07 2.28E+07 - - - 4.2943 0.8781 230117_WJC_METTL3_WT_vs_EV_F03.22251.22251.2 2.1 22-Jun R.LDDLC[160.03]SSIIDGR[166.11].F "sp|Q96NY9|MUS81_HUMAN,tr|H0YDE3|H0YDE3_HUMAN,tr|H0YDU2|H0YDU2_HUMAN,tr|H0YDK3|H0YDK3_HUMAN,tr|E9PRI1|E9PRI1_HUMAN" 5 1372.6532 -1 27033 22251 2 1372.650375 687.3339 Crossover junction endonuclease MUS81 OS=Homo sapiens OX=9606 GN=MUS81 PE=1 SV=3 3.93 3986.5 - 1.15E+07 - - - -2.0581 - 1.242 0.032 - 80.6 1 2 0 -0.0028 12 0 0 0 0.00E+00 0.00E+00 - - - -0.1533 1 230117_WJC_METTL3_WT_vs_EV_F03.22253.22253.2 4.54E-05 14/24 K.GIVSEEAYILFVR.K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1494.8082 0.67 27035 22253 2 1494.810182 748.4114 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.53 3986.6 - 1.53E+06 - - - 1.3059 - 2.694 0.476 - 817.5 1 2 0 0.002 13 0 0 0 6.92E+06 1.04E+07 - - - 5.0996 1 230117_WJC_METTL3_WT_vs_EV_F03.22254.22254.2 1.54E-14 21/38 K.MLLDPMGGIVMTNDGNAILR.E "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 2130.0636 -1 27036 22254 2 2130.068526 1066.0391 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.21 3986.7 - 1.51E+06 - - - 2.3351 - 3.818 0.741 - 1239.7 1 2 0 0.005 20 0 0 0 0.00E+00 0.00E+00 - - - 7.8062 1 230117_WJC_METTL3_WT_vs_EV_F03.22255.22255.2 1.37E-09 15/26 R.LLNNAFEELVAFQR.A "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1662.873 3.14 27037 22255 2 1662.874039 832.4438 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.53 3986.7 - 1.40E+06 - - - 0.6513 - 3.072 0.637 - 989.4 1 2 0 0.0011 14 0 0 0 4.69E+06 1.49E+06 - - - 6.562 1 230117_WJC_METTL3_WT_vs_EV_F03.22256.22256.2 0.00547 18-Nov K.LNMILVQILK.Q "sp|O14980|XPO1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 1183.7363 -1 27038 22256 2 1183.738717 592.8754 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3986.8 - 1.31E+06 - - - 2.0832 - 2.421 0.42 - 405.2 1 2 0 0.0025 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6104 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.22257.22257.3 0.000265 Jul-48 K.GIVSEEAYILFVR.K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1494.8082 0.9 27039 22257 3 1494.812383 499.2767 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.53 3986.9 - 1.23E+06 - - - 2.7783 - 1.588 0.361 - 52.5 1 2 0 0.0042 13 0 0 0 3.78E+06 4.20E+06 - - - 3.8175 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22258.22258.2 0.00714 20-Oct K.EYPFILDAFQR[166.11].E sp|P42285|MTREX_HUMAN 1 1407.7062 1.03 27040 22258 2 1407.709313 704.8604 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 3987 - 1.12E+06 - - - 2.1958 - 1.964 0.455 - 446.5 1 2 0 0.0031 11 0 0 0 5.28E+06 5.14E+06 - - - 4.2266 0.977 230117_WJC_METTL3_WT_vs_EV_F03.22259.22259.2 0.000174 26-Oct K.ELAEEGVLEEAEFY.N sp|Q14681|KCTD2_HUMAN 1 1626.7301 - 27041 22259 2 1626.732475 814.3723 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 3.46 3987.1 - 1.11E+06 - - - 1.4606 - 2.08 0.443 - 153.2 1 1 0 0.0024 14 0 0 0 - - - - - 4.1501 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.22260.22260.3 0.0002 15/60 R.FLLPEYLPYAGIFHER.G "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1964.0196 -1 27042 22260 3 1964.027595 655.6805 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 5.4 3987.1 - 1.08E+06 - - - 4.0606 - 2.725 0.472 - 258.7 1 2 0 0.008 16 0 0 0 0.00E+00 0.00E+00 - - - 6.3723 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.22261.22261.3 0.00378 Nov-40 K.TLSYLLPLLQR[166.11].L sp|Q9NUL7|DDX28_HUMAN 1 1325.7946 0.93 27043 22261 3 1325.797245 442.9388 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3987.3 - 874047 - - - 1.9626 - 2.108 0.367 - 186.1 1 2 0 0.0026 11 0 0 0 2.78E+06 2.98E+06 - - - 4.7495 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.22262.22262.2 2.60E-05 18-Nov R.SPNDLLALFR.Y "sp|Q92626|PXDN_HUMAN,tr|H7C1W1|H7C1W1_HUMAN" 2 1144.6241 0.1 27044 22262 2 1144.627695 573.3193 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 5.55 3987.4 - 860100 - - - 3.1775 - 2.284 0.405 - 482.9 1 2 0 0.0036 10 0 0 0 3.04E+06 2.90E+07 - - - 4.3366 1 230117_WJC_METTL3_WT_vs_EV_F03.22267.22267.3 2.91E-08 15/76 K.MLLDPMGGIVMTNDGNAILR[166.11].E "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 2140.0718 -1 27049 22267 3 2140.076345 714.3646 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.21 3988 - 402797 - - - 2.1135 - 2.749 0.541 - 204.9 1 2 0 0.0045 20 0 0 0 0.00E+00 0.00E+00 - - - 7.0236 1 230117_WJC_METTL3_WT_vs_EV_F03.22268.22268.2 2.08E-05 13/26 R.ISLPLPNFSSLNLR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1569.8879 1.67 27050 22268 2 1569.888692 785.9512 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3988.1 - 399487 - - - 0.5185 - 2.309 0.532 - 369.5 1 2 0 0.0008 14 0 0 0 1.08E+07 6.47E+06 - - - 5.07 1 230117_WJC_METTL3_WT_vs_EV_F03.22270.22270.3 4.04E-09 19/76 K.MLLDPMGGIVMTNDGNAILR.E "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 2130.0636 -1 27051 22270 3 2130.067852 711.0285 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.21 3988.3 - 4.29E+06 - - - 2.0187 - 3.597 0.624 - 522.5 1 2 0 0.0043 20 0 0 0 0.00E+00 0.00E+00 - - - 8.6013 1 230117_WJC_METTL3_WT_vs_EV_F03.22272.22272.2 3.05E-09 18/28 R.LPFLSSSNLSLDVLR.G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1659.9196 -1 27053 22272 2 1659.921924 830.9671 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3988.5 - 1.09E+07 - - - 1.4169 - 3.586 0.582 - 1196.8 1 2 0 0.0024 15 0 0 0 0.00E+00 0.00E+00 - - - 6.4786 1 230117_WJC_METTL3_WT_vs_EV_F03.22273.22273.2 3.60E-06 14/22 R.NLQNLLILTAIK[136.11].A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1360.8533 1.09 27054 22273 2 1360.855446 681.4339 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3988.5 - 8.35E+06 - - - 1.5498 - 2.644 0.537 - 576.6 1 2 0 0.0021 12 0 0 0 4.22E+07 3.87E+07 - - - 5.5649 1 230117_WJC_METTL3_WT_vs_EV_F03.22274.22274.2 1.74E-06 13/22 R.NLQNLLILTAIK.A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1352.8391 -1 27055 22274 2 1352.84095 677.4268 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3988.6 - 8.14E+06 - - - 1.3401 - 2.549 0.563 - 517 1 2 0 0.0018 12 0 0 0 0.00E+00 0.00E+00 - - - 5.6607 1 230117_WJC_METTL3_WT_vs_EV_F03.22275.22275.2 6.27E-08 17/28 R.LPFLSSSNLSLDVLR[166.11].G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1669.9278 -1 27056 22275 2 1669.930174 835.9712 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3988.6 - 8.14E+06 - - - 1.3965 - 3.296 0.639 - 917.7 1 2 0 0.0023 15 0 0 0 0.00E+00 0.00E+00 - - - 6.6923 0.9178 230117_WJC_METTL3_WT_vs_EV_F03.22278.22278.2 0.00497 18-Jul E.QEEDISSLIR.S sp|P78527|PRKDC_HUMAN 1 1188.5986 8.29 27059 22278 2 1188.600211 595.3066 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.14 3988.8 - 3.77E+06 - - - 1.3285 - 1.413 0.305 - 126.1 1 1 0 0.0016 10 0 0 0 3.52E+07 4.24E+06 - - - 2.2582 1 230117_WJC_METTL3_WT_vs_EV_F03.22279.22279.2 2.60E-08 13/28 K.GVFVQSVLPYFVATK.L "sp|Q53GQ0|DHB12_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN" 2 1653.913 -1 27060 22279 2 1653.914973 827.9638 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 8.59 3988.8 - 3.00E+06 - - - 1.1748 - 2.594 0.545 - 394.8 1 2 0 0.0019 15 0 0 0 0.00E+00 0.00E+00 - - - 5.4092 1 230117_WJC_METTL3_WT_vs_EV_F03.22281.22281.3 9.60E-10 18/64 R.AFLQGGQEATDIALLLR.D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1814.989 -1 27062 22281 3 1814.992677 606.0036 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3988.9 - 2.01E+06 - - - 1.9995 - 3.564 0.596 - 471.4 1 2 0 0.0036 17 0 0 0 0.00E+00 0.00E+00 - - - 8.3944 1 230117_WJC_METTL3_WT_vs_EV_F03.22283.22283.2 1.84E-05 14/22 K.LGTLSALDILIK.N "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1255.7751 -1 27064 22283 2 1255.77559 628.8948 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 5.84 3989.1 - 1.65E+06 - - - 0.3591 - 2.83 0.398 - 817.5 1 2 0 0.0005 12 0 0 0 0.00E+00 0.00E+00 - - - 4.7176 1 230117_WJC_METTL3_WT_vs_EV_F03.22285.22285.2 6.12E-10 19/32 R.AFLQGGQEATDIALLLR.D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1814.989 -1 27066 22285 2 1814.993905 908.5018 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3989.3 - 1.43E+06 - - - 2.676 - 3.707 0.682 - 1124.9 1 2 0 0.0049 17 0 0 0 0.00E+00 0.00E+00 - - - 7.298 1 230117_WJC_METTL3_WT_vs_EV_F03.22287.22287.2 7.12E-07 15/24 K.GNLEVLLFTIQSK[136.11].L "sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 5 1468.8381 -1 27068 22287 2 1468.842889 735.4263 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6 3989.5 - 1.29E+06 - - - 3.2733 - 3.167 0.585 - 991 1 2 0 0.0048 13 0 0 0 0.00E+00 0.00E+00 - - - 6.319 1 230117_WJC_METTL3_WT_vs_EV_F03.22288.22288.2 6.49E-09 15/24 K.GNLEVLLFTIQSK.L "sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 5 1460.8239 -1 27069 22288 2 1460.828386 731.4192 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6 3989.6 - 1.22E+06 - - - 3.0839 - 3.16 0.552 - 963 1 2 0 0.0045 13 0 0 0 0.00E+00 0.00E+00 - - - 6.0696 0.8729 230117_WJC_METTL3_WT_vs_EV_F03.22289.22289.2 20 18-Jul K.LNMILVQILK[136.11].Q "sp|O14980|XPO1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 1191.7505 -1 27070 22289 2 1191.753123 596.8825 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3989.7 - 1.11E+06 - - - 2.2421 - 0.905 0.019 - 54.2 1 2 0 0.0027 10 0 0 0 0.00E+00 0.00E+00 - - - -1.0981 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.22292.22292.3 4.51E-06 Nov-44 R.NLQNLLILTAIK.A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1352.8391 -1 27072 22292 3 1352.839926 451.9537 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3990 - 2.42E+06 - - - 0.5832 - 2.512 0.462 - 319.8 1 2 0 0.0008 12 0 0 0 0.00E+00 0.00E+00 - - - 6.2437 1 230117_WJC_METTL3_WT_vs_EV_F03.22293.22293.2 1.09E-07 14/22 K.TSDLIVLGLPWK.T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1340.7704 -1 27073 22293 2 1340.77315 671.3925 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3990 - 3.12E+07 - - - 2.06 - 2.733 0.63 - 657.4 1 2 0 0.0028 12 0 0 0 0.00E+00 0.00E+00 - - - 6.3387 1 230117_WJC_METTL3_WT_vs_EV_F03.22294.22294.2 4.35E-06 16/26 R.VISGVLQLGNIVFK[136.11].K sp|P35579|MYH9_HUMAN 1 1493.9061 -1 27074 22294 2 1493.908164 747.9603 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.72 3990 - 1.08E+07 - - - 1.3809 - 3.165 0.489 - 592.6 1 2 0 0.0021 14 0 0 0 0.00E+00 0.00E+00 - - - 5.5434 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.22296.22296.3 0.000458 13/52 R.VISGVLQLGNIVFK[136.11].K sp|P35579|MYH9_HUMAN 1 1493.9061 -1 27076 22296 3 1493.908685 498.976 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.72 3990.1 - 2.86E+06 - - - 1.7297 - 2.259 0.468 - 105.2 1 2 0 0.0026 14 0 0 0 0.00E+00 0.00E+00 - - - 5.9227 1 230117_WJC_METTL3_WT_vs_EV_F03.22298.22298.2 2.39E-11 17/32 K.LFEMVLGPAAYNVPLPK.K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1858.0063 -1 27078 22298 2 1858.011053 930.0104 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6 3990.3 - 2.25E+06 - - - 2.57 - 3.363 0.579 - 1000.3 1 2 0 0.0048 17 0 0 0 0.00E+00 0.00E+00 - - - 6.2978 1 230117_WJC_METTL3_WT_vs_EV_F03.22299.22299.3 4.93E-09 15/52 R.HPYFYAPELLFFAK.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 1741.8868 -1 27079 22299 3 1741.890828 581.6362 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6.75 3990.4 - 2.15E+06 - - - 2.3038 - 2.948 0.615 - 380.7 1 2 0 0.004 14 0 0 0 0.00E+00 0.00E+00 - - - 8.2687 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22300.22300.2 2.21E-06 28-Aug K.LTILQSLGDPLYYGK.L "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 1679.9134 -1 27080 22300 2 1679.91731 840.964 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.83 3990.5 - 1.94E+06 - - - 2.3132 - 1.976 0.488 - 171.9 1 2 0 0.0039 15 0 0 0 0.00E+00 0.00E+00 - - - 4.3186 0.9909 230117_WJC_METTL3_WT_vs_EV_F03.22301.22301.3 0.00102 13/64 K.LFEMVLGPAAYNVPLPK[136.11].K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1866.0205 -1 27081 22301 3 1866.032011 623.0141 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6 3990.5 - 5.61E+06 - - - 6.1805 - 1.704 0.33 - 95.8 1 2 0 0.0115 17 0 0 0 0.00E+00 0.00E+00 - - - 3.5624 1 230117_WJC_METTL3_WT_vs_EV_F03.22302.22302.2 4.58E-10 15/32 R.AFLQGGQEATDIALLLR[166.11].D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1824.9973 -1 27082 22302 2 1824.998592 913.5059 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3990.6 - 1.87E+06 - - - 0.6981 - 3.044 0.657 - 692.6 1 2 0 0.0013 17 0 0 0 0.00E+00 0.00E+00 - - - 6.63 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.22305.22305.3 0.178 Oct-48 K.GNLEVLLFTIQSK[136.11].L "sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 5 1468.8381 -1 27085 22305 3 1468.840437 490.62 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6 3990.8 - 1.33E+06 - - - 1.604 - 1.712 0.231 - 63.6 1 2 0 0.0024 13 0 0 0 0.00E+00 0.00E+00 - - - 2.5725 1 230117_WJC_METTL3_WT_vs_EV_F03.22306.22306.2 4.74E-08 16/24 R.DPTYFGPVLNYLR[166.11].H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1563.7961 0.71 27086 22306 2 1563.799089 782.9053 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3991 - 1.32E+06 - - - 1.912 - 3.02 0.649 - 989 1 2 0 0.003 13 0 0 0 6.60E+06 9.35E+06 - - - 6.6702 1 230117_WJC_METTL3_WT_vs_EV_F03.22307.22307.2 1.13E-06 15/26 R.ISLPLPNFSSLNLR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1579.8961 1.67 27087 22307 2 1579.897602 790.9554 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3991.1 - 1.29E+06 - - - 0.9203 - 2.491 0.526 - 546.1 1 2 0 0.0015 14 0 0 0 1.08E+07 6.47E+06 - - - 5.2159 0.9986 230117_WJC_METTL3_WT_vs_EV_F03.22308.22308.2 0.00051 22-Dec K.NVLITDFFGSVR.K "sp|Q92643|GPI8_HUMAN,tr|B1AK81|B1AK81_HUMAN,tr|A6NEM5|A6NEM5_HUMAN" 3 1366.7245 1.53 27088 22308 2 1366.728485 684.3695 GPI-anchor transamidase OS=Homo sapiens OX=9606 GN=PIGK PE=1 SV=2 5.84 3991.2 - 1.24E+06 - - - 2.915 - 2.09 0.225 - 388.6 1 2 0 0.004 12 0 0 0 4.06E+06 2.65E+06 - - - 2.6412 1 230117_WJC_METTL3_WT_vs_EV_F03.22310.22310.2 3.20E-09 13/32 K.LFEMVLGPAAYNVPLPK[136.11].K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1866.0205 -1 27090 22310 2 1866.021235 934.0175 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6 3991.4 - 1.19E+06 - - - 0.4057 - 2.641 0.625 - 439.2 1 2 0 0.0008 17 0 0 0 0.00E+00 0.00E+00 - - - 6.0446 0.8957 230117_WJC_METTL3_WT_vs_EV_F03.22312.22312.2 0.0125 18-Jul K.VEDLTFTSPF.C "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1154.5496 - 27091 22312 2 1154.549575 578.2821 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 3.67 3991.7 - 9.72E+06 - - - 0.0165 - 1.315 0.349 - 130.5 1 1 0 0 10 0 0 0 - - - - - 2.3831 1 230117_WJC_METTL3_WT_vs_EV_F03.22314.22314.2 2.28E-08 13/20 R.VLDLVEVLVTK[136.11].Q "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1234.7628 -1 27093 22314 2 1234.765651 618.3887 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.37 3991.8 - 4.09E+06 - - - 2.317 - 2.823 0.637 - 534.9 1 2 0 0.0029 11 0 0 0 0.00E+00 0.00E+00 - - - 6.5525 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.22315.22315.2 0.0189 20-Dec R.VLDLVEVLVTK.Q "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1226.7486 -1 27094 22315 2 1226.751745 614.3816 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.37 3991.8 - 2.94E+06 - - - 2.5718 - 1.224 0.367 - 207.1 1 2 0 0.0032 11 0 0 0 0.00E+00 0.00E+00 - - - 2.2975 1 230117_WJC_METTL3_WT_vs_EV_F03.22318.22318.2 5.39E-05 22-Dec R.SQALIEELLLYK.R sp|Q5VT52|RPRD2_HUMAN 1 1418.8021 -1 27097 22318 2 1418.804979 710.4083 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3992 - 2.39E+06 - - - 2.0419 - 2.489 0.439 - 439.1 1 2 0 0.0029 12 0 0 0 0.00E+00 0.00E+00 - - - 4.6819 1 230117_WJC_METTL3_WT_vs_EV_F03.22322.22322.2 0.00117 13/20 K.FVDILTNWYVR.M "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1424.7452 -1 27101 22322 2 1424.749089 713.3799 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.84 3992.3 - 1.71E+06 - - - 2.7043 - 2.639 0.544 - 665.9 1 2 0 0.0039 11 0 0 0 0.00E+00 0.00E+00 - - - 5.6829 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.22324.22324.3 0.00618 17/72 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 27103 22324 3 1911.185542 638.0676 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3992.5 - 1.62E+06 - - - 2.4435 - 2.429 0.391 - 286.4 1 2 0 0.0047 19 0 0 0 0.00E+00 0.00E+00 - - - 5.0783 1 230117_WJC_METTL3_WT_vs_EV_F03.22325.22325.2 9.63E-07 15/26 K.TLAESALQLLYTAK.E sp|Q9Y490|TLN1_HUMAN 1 1520.845 -1 27104 22325 2 1520.850429 761.4298 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.66 3992.6 - 1.59E+06 - - - 3.5632 - 2.874 0.518 - 461.3 1 2 0 0.0054 14 0 0 0 0.00E+00 0.00E+00 - - - 5.5145 1 230117_WJC_METTL3_WT_vs_EV_F03.22327.22327.2 2.47E-05 15/24 R.AIAYLFPSGLFEK[136.11].R sp|P82933|RT09_HUMAN 1 1462.7952 1.15 27106 22327 2 1462.800029 732.4049 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 6.05 3992.7 - 1.55E+06 - - - 3.3333 - 3.024 0.412 - 855.4 1 2 0 0.0049 13 0 0 0 1.47E+07 1.28E+07 - - - 4.9226 1 230117_WJC_METTL3_WT_vs_EV_F03.22328.22328.2 3.24E-09 13/22 K.FFDDPMLLELAK.Q "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1437.7214 -1 27107 22328 2 1437.722547 719.868 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.03 3992.8 - 1.35E+06 - - - 0.8054 - 2.703 0.576 - 250.3 1 2 0 0.0012 12 0 0 0 0.00E+00 0.00E+00 - - - 5.9113 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22330.22330.2 0.00643 15/36 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 27109 22330 2 1911.184877 956.5977 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3993 - 1.30E+06 - - - 2.0956 - 2.142 0.454 - 329.1 1 2 0 0.004 19 0 0 0 0.00E+00 0.00E+00 - - - 4.2658 1 230117_WJC_METTL3_WT_vs_EV_F03.22331.22331.2 2.11E-06 14/24 R.DPTYFGPVLNYLR.H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1553.7878 0.71 27110 22331 2 1553.79047 777.9012 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3993.1 - 1.23E+06 - - - 1.6997 - 2.517 0.534 - 743.1 1 2 0 0.0026 13 0 0 0 6.60E+06 9.30E+06 - - - 5.3534 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.22334.22334.2 3.88E-05 13/26 K.TLAESALQLLYTAK[136.11].E sp|Q9Y490|TLN1_HUMAN 1 1528.8592 -1 27112 22334 2 1528.85993 765.4369 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.66 3993.5 - 793518 - - - 0.4709 - 2.109 0.434 - 342 1 2 0 0.0007 14 0 0 0 0.00E+00 0.00E+00 - - - 4.1189 1 230117_WJC_METTL3_WT_vs_EV_F03.22335.22335.2 5.48E-12 14/26 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 8.69 27113 22335 2 1537.77233 769.8922 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3993.5 - 3.08E+07 - - - 1.6478 - 3.103 0.691 - 609 1 2 0 0.0025 14 0 0 0 1.09E+08 1.25E+07 - - - 6.9856 1 230117_WJC_METTL3_WT_vs_EV_F03.22337.22337.3 5.85E-05 Dec-52 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 8.39 27115 22337 3 1537.773023 513.5972 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3993.6 - 5.16E+06 - - - 2.0985 - 2.609 0.505 - 238.2 1 2 0 0.0032 14 0 0 0 1.54E+07 1.84E+06 - - - 6.7178 1 230117_WJC_METTL3_WT_vs_EV_F03.22338.22338.2 4.00E-05 13/28 R.ATSFLLALEPELEAR.L "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1658.8879 -1 27116 22338 2 1658.889197 830.4512 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.25 3993.6 - 3.39E+06 - - - 0.7595 - 2.952 0.558 - 505.9 1 2 0 0.0013 15 0 0 0 0.00E+00 0.00E+00 - - - 5.8233 1 230117_WJC_METTL3_WT_vs_EV_F03.22341.22341.2 1.65E-10 17/28 R.ATSFLLALEPELEAR[166.11].L "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1668.8962 -1 27119 22341 2 1668.899174 835.4554 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.25 3993.8 - 2.55E+06 - - - 1.7778 - 3.372 0.557 - 1040.4 1 2 0 0.003 15 0 0 0 0.00E+00 0.00E+00 - - - 6.1424 0.8877 230117_WJC_METTL3_WT_vs_EV_F03.22345.22345.3 2.23 Aug-48 R.GNTAAYLLYAFTR.L sp|P54136|SYRC_HUMAN 1 1459.746 -1 27123 22345 3 1459.748879 487.5893 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.59 3994.1 - 1.36E+06 - - - 1.9962 - 1.269 0.072 - 72.6 1 2 0 0.0029 13 0 0 0 0.00E+00 0.00E+00 - - - -0.0122 0.9893 230117_WJC_METTL3_WT_vs_EV_F03.22346.22346.3 0.0923 Sep-60 K.IFEIFGPVAHPFYVLR.F sp|Q96HR8|NAF1_HUMAN 1 1904.0349 -1 27124 22346 3 1904.041066 635.6856 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 6.75 3994.2 - 1.36E+06 - - - 3.251 - 1.665 0.186 - 75.9 1 2 0 0.0062 16 0 0 0 0.00E+00 0.00E+00 - - - 1.9201 0.9971 230117_WJC_METTL3_WT_vs_EV_F03.22349.22349.2 2.38E-07 26-Nov K.DAAGIAMEAIAFAR.N sp|P08240|SRPRA_HUMAN 1 1405.7024 2.95 27127 22349 2 1405.710429 703.8585 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 4.37 3994.4 - 1.15E+06 - - - 5.7224 - 1.92 0.52 - 293.8 1 2 0 0.008 14 0 0 0 2.36E+06 8.00E+05 - - - 4.5162 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.22350.22350.3 0.00448 16/56 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 2.2 27128 22350 3 1529.919893 510.9796 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3994.5 - 1.11E+06 - - - 1.9674 - 2.638 0.438 - 331 1 2 0 0.003 15 0 0 0 1.45E+07 6.60E+06 - - - 5.9536 1 230117_WJC_METTL3_WT_vs_EV_F03.22355.22355.2 3.07E-08 20/28 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 -1 27132 22355 2 1519.911572 760.9616 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3995 - 3.05E+06 - - - 1.9468 - 3.185 0.607 - 1683.5 1 2 0 0.003 15 0 0 0 0.00E+00 0.00E+00 - - - 6.3715 1 230117_WJC_METTL3_WT_vs_EV_F03.22356.22356.3 1.93E-06 16/56 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 2.2 27133 22356 3 1519.912647 507.6435 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3995 - 4.67E+06 - - - 2.6541 - 2.579 0.552 - 291.6 1 2 0 0.004 15 0 0 0 1.45E+07 6.60E+06 - - - 7.1653 1 230117_WJC_METTL3_WT_vs_EV_F03.22357.22357.2 2.76E-06 13/22 K.AYVVLGQFLVLK[136.11].K sp|O75531|BAF_HUMAN 1 1356.8261 -1 27134 22357 2 1356.829807 679.4203 Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1 8.63 3995.1 - 3.95E+06 - - - 2.7623 - 2.474 0.543 - 582.2 1 2 0 0.0037 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4338 1 230117_WJC_METTL3_WT_vs_EV_F03.22358.22358.3 9.54E-06 15/52 K.ILGGSVLHLVLALR.G sp|Q15843|NEDD8_HUMAN 1 1459.9239 -1 27135 22358 3 1459.927085 487.6486 NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1 9.76 3995.1 - 2.50E+06 - - - 2.2029 - 2.906 0.517 - 335.7 1 2 0 0.0032 14 0 0 0 0.00E+00 0.00E+00 - - - 7.1381 1 230117_WJC_METTL3_WT_vs_EV_F03.22359.22359.2 5.41E-06 22-Dec K.AYVVLGQFLVLK.K sp|O75531|BAF_HUMAN 1 1348.8119 -1 27136 22359 2 1348.815154 675.4132 Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1 8.63 3995.2 - 2.17E+06 - - - 2.4429 - 2.361 0.515 - 441.8 1 2 0 0.0033 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1042 1 230117_WJC_METTL3_WT_vs_EV_F03.22360.22360.2 1.50E-08 22-Nov K.NTPFLYDLVMTH.A "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|E9PIC4|E9PIC4_HUMAN,tr|E9PNS2|E9PNS2_HUMAN,tr|E9PNS6|E9PNS6_HUMAN,tr|C9JAJ9|C9JAJ9_HUMAN,tr|E9PC52|E9PC52_HUMAN" 7 1449.6962 - 27137 22360 2 1449.70128 725.8554 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.08 3995.3 - 2.08E+06 - - - 3.4787 - 2.421 0.593 - 504.5 1 1 0 0.005 12 0 0 0 - - - - - 5.7457 1 230117_WJC_METTL3_WT_vs_EV_F03.22361.22361.3 1.93E-07 17/44 K.FFEVILIDPFHK[136.11].A "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 4 1511.8268 -1 27138 22361 3 1511.830439 504.9495 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 5.32 3995.3 - 1.79E+06 - - - 2.415 - 2.636 0.538 - 324.5 1 2 0 0.0037 12 0 0 0 0.00E+00 0.00E+00 - - - 7.2238 1 230117_WJC_METTL3_WT_vs_EV_F03.22362.22362.3 3.29E-06 16/44 K.FFEVILIDPFHK.A "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 4 1503.8126 1.03 27139 22362 3 1503.814675 502.2781 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 5.32 3995.4 - 1.59E+06 - - - 1.3878 - 2.7 0.563 - 260.5 1 2 0 0.0021 12 0 0 0 1.86E+07 1.80E+07 - - - 7.5695 1 230117_WJC_METTL3_WT_vs_EV_F03.22363.22363.3 4.64E-05 13/44 K.AILC[160.03]LLLGGVER.D "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1312.7537 -1 27140 22363 3 1312.756151 438.5918 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 6.04 3995.5 - 1.48E+06 - - - 1.8724 - 2.454 0.503 - 270.8 1 2 0 0.0025 12 0 0 0 0.00E+00 0.00E+00 - - - 6.6356 1 230117_WJC_METTL3_WT_vs_EV_F03.22364.22364.3 1.01E-05 21/52 K.ILGGSVLHLVLALR[166.11].G sp|Q15843|NEDD8_HUMAN 1 1469.9321 -1 27141 22364 3 1469.936199 490.9847 NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1 9.76 3995.6 - 1.36E+06 - - - 2.762 - 3.329 0.552 - 727.9 1 2 0 0.0041 14 0 0 0 0.00E+00 0.00E+00 - - - 7.8893 1 230117_WJC_METTL3_WT_vs_EV_F03.22365.22365.3 2.96E-12 22/64 R.LLQQVGTVAQLWIYPVK.S "sp|Q5VT66|MARC1_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 2 1955.1244 -1 27142 22365 3 1955.130787 652.7154 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 8.59 3995.7 - 1.30E+06 - - - 3.2566 - 3.806 0.611 - 613.7 1 2 0 0.0064 17 0 0 0 0.00E+00 0.00E+00 - - - 8.7269 1 230117_WJC_METTL3_WT_vs_EV_F03.22366.22366.2 5.58E-08 18/28 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 -1 27143 22366 2 1529.921536 765.9657 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3995.8 - 1.30E+06 - - - 3.0413 - 2.97 0.585 - 965.9 1 2 0 0.0047 15 0 0 0 0.00E+00 0.00E+00 - - - 6.0366 1 230117_WJC_METTL3_WT_vs_EV_F03.22369.22369.2 0.000179 14/26 K.YVVLSYLGLLSQEK.L "sp|Q9BXK5|B2L13_HUMAN,tr|F6VJB4|F6VJB4_HUMAN,tr|A0A0A0MR90|A0A0A0MR90_HUMAN,tr|F2Z2C3|F2Z2C3_HUMAN,tr|E9PDD6|E9PDD6_HUMAN,tr|A0A087WW80|A0A087WW80_HUMAN" 6 1610.892 -1 27146 22369 2 1610.899241 806.4533 Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13 PE=1 SV=1 6 3996.1 - 1.11E+06 - - - 4.5199 - 2.64 0.487 - 608.6 1 2 0 0.0073 14 0 0 0 0.00E+00 0.00E+00 - - - 5.0718 0.9102 230117_WJC_METTL3_WT_vs_EV_F03.22373.22373.2 2.29 Mar-36 R.LPVVIGGLLDVDC[160.03]SEDVIK.N "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2040.0813 -1 27150 22373 2 2040.08247 1021.0479 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 3.84 3996.5 - 737827 - - - 0.5764 - 0.976 0.092 - 10.9 18 2 0 0.0012 19 0 0 0 0.00E+00 0.00E+00 - - - -0.9003 1 230117_WJC_METTL3_WT_vs_EV_F03.22377.22377.2 4.79E-06 18-Nov R.C[160.03]WAGSLWLFK[136.11].D sp|Q9BQA1|MEP50_HUMAN 1 1274.6362 -1 27153 22377 2 1274.639366 638.3254 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 3996.9 - 4.24E+07 - - - 2.5231 - 2.234 0.605 - 329.4 1 2 0 0.0032 10 0 0 0 0.00E+00 0.00E+00 - - - 5.7522 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.22378.22378.2 0.0225 16-Aug K.LLLPWLEAR.L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1109.6597 8.24 27154 22378 2 1109.662783 555.8371 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6 3996.9 - 2.03E+07 - - - 2.7639 - 1.931 0.322 - 314.4 1 2 0 0.0031 9 0 0 0 2.44E+08 2.96E+07 - - - 3.3221 1 230117_WJC_METTL3_WT_vs_EV_F03.22379.22379.2 1.08E-07 18-Nov R.C[160.03]WAGSLWLFK.D sp|Q9BQA1|MEP50_HUMAN 1 1266.6219 0.47 27155 22379 2 1266.625533 634.3183 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 3997 - 1.90E+07 - - - 2.8288 - 2.332 0.551 - 299.2 1 2 0 0.0036 10 0 0 0 3.21E+07 6.88E+07 - - - 5.473 1 230117_WJC_METTL3_WT_vs_EV_F03.22380.22380.2 2.15E-05 17/30 K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 -1 27156 22380 2 1701.892263 851.9512 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3997 - 5.21E+06 - - - 2.5766 - 3.167 0.57 - 707.8 1 2 0 0.0044 16 0 0 0 0.00E+00 0.00E+00 - - - 6.0838 1 230117_WJC_METTL3_WT_vs_EV_F03.22382.22382.2 0.000595 14/30 K.AAGVNVEPFWPGLFAK[136.11].A sp|P05386|RLA1_HUMAN 1 1709.9021 -1 27158 22382 2 1709.905547 855.9583 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3997.1 - 4.05E+06 - - - 2.0288 - 2.946 0.516 - 441 1 2 0 0.0035 16 0 0 0 0.00E+00 0.00E+00 - - - 5.5074 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.22383.22383.2 0.018 18-Nov R.AALLELWELR[166.11].R "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1222.6949 -1 27159 22383 2 1222.6993 612.3547 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 3997.2 - 3.18E+06 - - - 3.5749 - 2.715 0.332 - 435.4 1 2 0 0.0044 10 0 0 0 0.00E+00 0.00E+00 - - - 4.2797 1 230117_WJC_METTL3_WT_vs_EV_F03.22387.22387.2 8.62E-06 22-Dec R.LLDTAFDLDVFK[136.11].N "sp|Q02218|ODO1_HUMAN,tr|E9PFG7|E9PFG7_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 4 1403.7428 -1 27163 22387 2 1403.747971 702.8787 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 3.93 3997.4 - 1.78E+06 - - - 3.6958 - 2.618 0.567 - 395.2 1 2 0 0.0052 12 0 0 0 0.00E+00 0.00E+00 - - - 5.7595 1 230117_WJC_METTL3_WT_vs_EV_F03.22389.22389.2 1.53E-08 15/24 R.DLYEDELVPLFEK[136.11].A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1616.8065 -1 27165 22389 2 1616.811531 809.4105 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3997.6 - 1.55E+06 - - - 3.108 - 2.585 0.515 - 590.2 1 2 0 0.005 13 0 0 0 0.00E+00 0.00E+00 - - - 5.2807 1 230117_WJC_METTL3_WT_vs_EV_F03.22391.22391.2 5.67E-06 22-Nov R.LLDTAFDLDVFK.N "sp|Q02218|ODO1_HUMAN,tr|E9PFG7|E9PFG7_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 4 1395.7286 -1 27167 22391 2 1395.731077 698.8716 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 3.93 3997.7 - 1.39E+06 - - - 1.7869 - 2.412 0.487 - 350.6 1 2 0 0.0025 12 0 0 0 0.00E+00 0.00E+00 - - - 4.9538 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.22394.22394.2 0.531 13/20 R.IPLLLTSLSFK[136.11].V "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1238.773 -1 27170 22394 2 1238.776899 620.3938 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.75 3998.1 - 949353 - - - 3.179 - 2.534 0.381 - 591.3 1 2 0 0.0039 11 0 0 0 0.00E+00 0.00E+00 - - - 4.3692 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22398.22398.2 0.00101 14/24 R.DILVEADSLWVVK[136.11].M sp|Q15208|STK38_HUMAN 1 1493.8221 -1 27173 22398 2 1493.825409 747.9183 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.03 3998.4 - 1.24E+07 - - - 2.2178 - 2.838 0.342 - 612.9 1 2 0 0.0033 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2431 1 230117_WJC_METTL3_WT_vs_EV_F03.22399.22399.2 7.08E-07 14/24 R.DLYEDELVPLFEK.A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1608.7923 -1 27174 22399 2 1608.795073 805.4034 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3998.4 - 1.06E+07 - - - 1.7199 - 2.667 0.596 - 526.1 1 2 0 0.0028 13 0 0 0 0.00E+00 0.00E+00 - - - 5.9598 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.22400.22400.2 0.0621 16-Aug K.AFLLESLLK.N sp|Q96JM3|CHAP1_HUMAN 1 1032.6219 4.43 27175 22400 2 1032.624278 517.3182 Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2 6.05 3998.4 - 6.20E+06 - - - 2.2709 - 1.613 0.37 - 209 1 2 0 0.0023 9 0 0 0 1.12E+07 2.52E+06 - - - 3.1562 1 230117_WJC_METTL3_WT_vs_EV_F03.22401.22401.2 1.33E-06 22-Nov K.GILTVDELLAIR.L sp|P13473|LAMP2_HUMAN 1 1311.7762 -1 27176 22401 2 1311.779135 656.8954 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 4.37 3998.5 - 3.77E+06 - - - 2.2359 - 2.628 0.536 - 539.3 1 2 0 0.0029 12 0 0 0 0.00E+00 0.00E+00 - - - 5.5413 1 230117_WJC_METTL3_WT_vs_EV_F03.22402.22402.2 1.96E-08 28-Dec R.ELIQTSALNFLTPLR.N "sp|Q9Y371|SHLB1_HUMAN,tr|A0A087WW40|A0A087WW40_HUMAN" 2 1714.9618 -1 27177 22402 2 1714.967436 858.4882 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 6.1 3998.6 - 2.89E+06 - - - 3.3033 - 2.784 0.592 - 407.5 1 2 0 0.0057 15 0 0 0 0.00E+00 0.00E+00 - - - 5.929 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.22403.22403.3 0.00957 Dec-48 R.DLYEDELVPLFEK.A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1608.7923 -1 27178 22403 3 1608.79721 537.2714 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3998.6 - 2.54E+06 - - - 3.0482 - 2.246 0.351 - 248 1 2 0 0.0049 13 0 0 0 0.00E+00 0.00E+00 - - - 4.6458 1 230117_WJC_METTL3_WT_vs_EV_F03.22406.22406.2 4.55E-07 14/26 R.DYLHLPPEIVPATL.H "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1576.8501 - 27181 22406 2 1576.85577 789.4323 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.35 3998.8 - 2.26E+06 - - - 3.5989 - 2.669 0.565 - 633.5 1 1 0 0.0057 14 0 0 0 - - - - - 5.6758 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.22409.22409.3 2.63E-05 Oct-48 R.DLYEDELVPLFEK[136.11].A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1616.8065 -1 27184 22409 3 1616.810488 539.9428 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3999 - 2.03E+06 - - - 2.4629 - 2.178 0.467 - 156.1 1 2 0 0.004 13 0 0 0 0.00E+00 0.00E+00 - - - 5.856 1 230117_WJC_METTL3_WT_vs_EV_F03.22410.22410.2 3.58E-07 20/32 R.LVSDIIDPVALEIPLSK.N "sp|Q5UIP0|RIF1_HUMAN,tr|H7C2B5|H7C2B5_HUMAN" 2 1821.0499 -1 27185 22410 2 1821.055399 911.5322 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 4.03 3999.1 - 1.77E+06 - - - 3.0104 - 3.467 0.569 - 1026.3 1 2 0 0.0055 17 0 0 0 0.00E+00 0.00E+00 - - - 6.2986 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.22425.22425.2 2.02E-05 28-Jul R.LTSFIGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1516.8865 -1 27194 22425 2 1516.891236 759.4505 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 4000.1 - 4.04E+07 - - - 3.1347 - 1.573 0.533 - 137 1 2 0 0.0048 15 0 0 0 0.00E+00 0.00E+00 - - - 4.0899 0.9984 230117_WJC_METTL3_WT_vs_EV_F03.22440.22440.3 0.00017 Nov-52 R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 -1 27202 22440 3 1486.883064 496.6312 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4001 - 2.75E+06 - - - 7.5131 - 2.176 0.519 - 149.5 1 2 0 0.0112 14 0 0 0 0.00E+00 0.00E+00 - - - 6.3894 1 230117_WJC_METTL3_WT_vs_EV_F03.22443.22443.2 2.78E-08 15/28 R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 -1 27205 22443 2 1555.910925 778.9577 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 4001.4 - 1.29E+06 - - - 6.539 - 2.826 0.494 - 590.2 1 2 0 0.0102 15 0 0 0 0.00E+00 0.00E+00 - - - 5.2406 0.9995 230117_WJC_METTL3_WT_vs_EV_F03.22622.22622.2 0.0199 16-Oct R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.46 27257 22622 2 1108.65535 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4032 - 1.60E+08 - - - 1.9095 - 2.224 0.272 - 247.2 1 2 0 0.0021 9 0 0 0 3.79E+08 2.59E+08 - - - 3.3618 0.9996 230117_WJC_METTL3_WT_vs_EV_F03.22623.22623.2 0.00146 16-Nov R.IAIYELLFK[136.11].E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1116.6674 1.46 27258 22623 2 1116.669181 559.341 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4032.1 - 1.13E+08 - - - 1.5654 - 2.22 0.315 - 339.2 1 2 0 0.0017 9 0 0 0 3.79E+08 2.59E+08 - - - 3.6743 1 230117_WJC_METTL3_WT_vs_EV_F03.22624.22624.2 4.02E-05 26-Dec K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.54 27259 22624 2 1618.968006 810.4902 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4032.1 - 2.44E+07 - - - 1.3663 - 2.316 0.515 - 270.4 1 2 0 0.0022 14 0 0 0 6.53E+07 4.25E+07 - - - 4.9516 1 230117_WJC_METTL3_WT_vs_EV_F03.22625.22625.2 6.13E-08 14/28 R.LTSFIGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1516.8865 7.19 27260 22625 2 1516.888574 759.4505 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 4032.1 - 2.37E+07 - - - 1.3798 - 2.913 0.529 - 535.9 1 2 0 0.0021 15 0 0 0 5.84E+07 8.11E+06 - - - 5.5762 1 230117_WJC_METTL3_WT_vs_EV_F03.22626.22626.3 3.91E-06 19/56 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 8.19 27261 22626 3 1581.911468 528.3103 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4032.2 - 2.10E+07 - - - 1.5557 - 3.419 0.549 - 731 1 2 0 0.0025 15 0 0 0 4.62E+07 5.64E+06 - - - 7.8679 1 230117_WJC_METTL3_WT_vs_EV_F03.22630.22630.2 6.95E-11 17/30 K.LGFAGLVQEISFGTTK.D "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1666.893 5.77 27265 22630 2 1666.895024 834.4538 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 4032.4 - 1.65E+07 - - - 1.2004 - 3.346 0.615 - 765.9 1 2 0 0.002 16 0 0 0 4.14E+07 7.18E+06 - - - 6.5521 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22632.22632.2 3.53E-05 26-Oct K.ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1626.98 1.54 27267 22632 2 1626.981752 814.4973 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4032.4 - 1.51E+07 - - - 1.0805 - 1.941 0.485 - 219.2 1 2 0 0.0018 14 0 0 0 6.53E+07 4.24E+07 - - - 4.2869 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.22635.22635.3 0.0308 Sep-52 K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.49 27270 22635 3 1618.968397 540.6625 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4032.5 - 1.13E+07 - - - 1.6078 - 1.669 0.317 - 99.4 1 2 0 0.0026 14 0 0 0 2.57E+07 1.73E+07 - - - 3.4348 0.9998 230117_WJC_METTL3_WT_vs_EV_F03.22638.22638.3 0.00113 Oct-52 K.ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1626.98 1.49 27273 22638 3 1626.982383 543.3339 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4032.7 - 8.40E+06 - - - 1.4684 - 1.862 0.412 - 120.8 1 2 0 0.0024 14 0 0 0 2.57E+07 1.73E+07 - - - 4.7848 1 230117_WJC_METTL3_WT_vs_EV_F03.22639.22639.2 8.73E-07 24-Sep K.SLEEIYLFSLPIK[136.11].E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN,tr|H3BNG3|H3BNG3_HUMAN,tr|H0YE27|H0YE27_HUMAN" 7 1558.8738 0.21 27274 22639 2 1558.876668 780.4442 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.53 4032.7 - 7.84E+06 - - - 1.8417 - 2.205 0.494 - 219 1 2 0 0.0029 13 0 0 0 4.81E+06 2.26E+07 - - - 4.7182 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.22640.22640.2 0.000675 May-32 R.WVGGPEIELIAIATGGR.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1737.9414 5.74 27275 22640 2 1737.943721 869.978 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 4032.8 - 7.40E+06 - - - 1.3527 - 1.441 0.575 - 55.3 1 2 0 0.0024 17 0 0 0 2.20E+07 3.83E+06 - - - 4.1854 0.9978 230117_WJC_METTL3_WT_vs_EV_F03.22645.22645.3 0.0111 Sep-56 R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 93.94 27279 22645 3 1555.907667 519.6409 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 4033.2 - 696278 - - - 4.445 - 1.38 0.394 - 34.5 1 2 0 0.0069 15 0 0 0 1.98E+07 2.11E+05 - - - 3.7712 1 230117_WJC_METTL3_WT_vs_EV_F03.22647.22647.2 4.60E-05 13/26 R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 12.17 27281 22647 2 1486.877799 744.4432 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4033.5 - 351907 - - - 3.9721 - 2.645 0.577 - 548.5 1 2 0 0.0059 14 0 0 0 1.25E+07 1.03E+06 - - - 5.7417 1 230117_WJC_METTL3_WT_vs_EV_F03.22653.22653.2 1.59E-05 13/28 R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 3.03 27287 22653 2 1555.906843 778.9577 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 4034.3 - 200880 - - - 3.9154 - 2.787 0.619 - 552.7 1 2 0 0.0061 15 0 0 0 1.94E+06 6.42E+05 - - - 6.1309 0.9972 230117_WJC_METTL3_WT_vs_EV_F03.22661.22661.2 0.0646 28-Sep R.QVLLSAAEAAEVILR[166.11].V sp|P78371|TCPB_HUMAN 1 1591.9173 8.13 27295 22661 2 1591.925232 796.9659 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4035.3 - 71074.8 - - - 4.9971 - 2.289 0.335 - 247.2 1 2 0 0.008 15 0 0 0 7.08E+07 8.70E+06 - - - 3.5488 1 230117_WJC_METTL3_WT_vs_EV_F03.22754.22754.2 0.0421 28-Nov R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 13.28 27304 22754 2 1581.911458 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4053.3 - 0 - - - 1.5494 - 2.624 0.536 - 383.1 1 2 0 0.0025 15 0 0 0 8.04E+06 6.05E+05 - - - 5.3709 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.22803.22803.2 0.0528 16-Oct R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.47 27309 22803 2 1108.656288 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4062.5 - 204855 - - - 2.7556 - 1.912 0.315 - 260.4 1 2 0 0.0031 9 0 0 0 3.18E+07 2.16E+07 - - - 3.2418 0.9992 230117_WJC_METTL3_WT_vs_EV_F03.22804.22804.2 0.00305 16-Aug R.IAIYELLFK[136.11].E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1116.6674 1.47 27310 22804 2 1116.67036 559.341 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4062.6 - 154272 - - - 2.6212 - 1.966 0.275 - 165.3 1 2 0 0.0029 9 0 0 0 3.17E+07 2.16E+07 - - - 3.0269 1 230117_WJC_METTL3_WT_vs_EV_F03.22815.22815.2 4.79E-07 30-Aug K.LGFAGLVQEISFGTTK.D "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1666.893 10.51 27315 22815 2 1666.898492 834.4538 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 4064.3 - 67079.2 - - - 3.281 - 1.831 0.602 - 169.5 1 2 0 0.0055 16 0 0 0 3.27E+06 3.11E+05 - - - 4.9727 0.9439 230117_WJC_METTL3_WT_vs_EV_F03.22817.22817.2 5.35 26-Apr R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 11.99 27317 22817 2 1486.877348 744.4432 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4064.6 - 55519.8 - - - 3.6688 - 1.033 0.116 - 48.5 1 2 0 0.0055 14 0 0 0 2.74E+06 2.29E+05 - - - -0.0225 0.9999 230117_WJC_METTL3_WT_vs_EV_F03.22913.22913.3 1.89E-06 16/52 R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 3.27 27328 22913 3 1486.877955 496.6312 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4082 - 816834 - - - 4.077 - 2.892 0.553 - 329.2 1 2 0 0.0061 14 0 0 0 1.17E+06 3.58E+05 - - - 7.5259 1 230117_WJC_METTL3_WT_vs_EV_F03.22914.22914.3 1.71E-08 26/56 R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 999 27329 22914 3 1555.906798 519.6409 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 4082.2 - 1.84E+06 - - - 3.8865 - 3.765 0.607 - 690.4 1 2 0 0.006 15 0 0 0 2.36E+06 0.00E+00 - - - 8.7651 1 230117_WJC_METTL3_WT_vs_EV_F03.22916.22916.2 1.97E-05 15/24 K.SLEEIYLFSLPIK.E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN,tr|H3BNG3|H3BNG3_HUMAN,tr|H0YE27|H0YE27_HUMAN" 7 1550.8596 0.22 27331 22916 2 1550.872301 776.4371 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.53 4082.4 - 492170 - - - 8.1916 - 2.775 0.494 - 621.9 1 2 0 0.0127 13 0 0 0 3.42E+05 1.53E+06 - - - 5.3052 1 230117_WJC_METTL3_WT_vs_EV_F03.22933.22933.2 0.00753 19/28 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 7.83 27337 22933 2 1581.913505 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4084.6 - 356538 - - - 2.8434 - 3.56 0.517 - 1269.9 1 2 0 0.0045 15 0 0 0 2.24E+07 2.86E+06 - - - 5.9799 1 230117_WJC_METTL3_WT_vs_EV_F03.22934.22934.2 0.000201 18-Sep R.DEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1329.6605 -1 27338 22934 2 1329.664416 665.8375 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 4084.8 - 9705.72 - - - 2.9421 - 2.226 0.501 - 354.7 1 2 0 0.0039 10 0 0 0 0.00E+00 0.00E+00 - - - 4.9738 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.22935.22935.2 0.00694 22-Jun R.VDIGDTIIYLVH.- "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 8 1356.7289 - 27339 22935 2 1356.732568 679.3717 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.2 4084.9 - 13115.2 - - - 2.691 - 1.577 0.456 - 130.5 1 2 0 0.0037 12 0 0 0 - - - - - 3.6064 0.9933 230117_WJC_METTL3_WT_vs_EV_F03.22939.22939.2 0.207 22-Apr R.AAVESLGFILFR.T "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN" 11 1321.7394 -1 27343 22939 2 1321.74115 661.877 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 6.05 4085.4 - 5831 - - - 1.3066 - 0.859 0.287 - 44 1 2 0 0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 0.7603 0.9975 230117_WJC_METTL3_WT_vs_EV_F03.22978.22978.2 0.0188 28-May R.EFSITDVVPYPISLR.W "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1734.9192 999 27350 22978 2 1734.920199 868.4669 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.37 4092.1 - 0 - - - 0.5539 - 1.203 0.291 - 56.3 1 2 0 0.001 15 0 0 0 5.00E+05 0.00E+00 - - - 1.6444 0.8645 230117_WJC_METTL3_WT_vs_EV_F03.22986.22986.2 5.76 16-Mar R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.47 27353 22986 2 1108.656282 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4093.1 - 48448 - - - 2.7502 - 0.635 0.193 - 17.8 2 2 0 0.003 9 0 0 0 2.38E+07 1.62E+07 - - - -0.9828 0.9962 230117_WJC_METTL3_WT_vs_EV_F03.22997.22997.2 0.00982 28-May R.LTSFIGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1516.8865 8.31 27358 22997 2 1516.891921 759.4505 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 4094.8 - 98236.3 - - - 3.5863 - 1.353 0.303 - 64.7 1 2 0 0.0054 15 0 0 0 3.38E+06 4.06E+05 - - - 2.0205 0.9997 230117_WJC_METTL3_WT_vs_EV_F03.23003.23003.3 0.0154 Dec-56 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 6.26 27360 23003 3 1581.914444 528.3103 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4095.6 - 135166 - - - 3.437 - 2.477 0.388 - 256.5 1 2 0 0.0054 15 0 0 0 1.28E+07 2.05E+06 - - - 5.2311 0.994 230117_WJC_METTL3_WT_vs_EV_F03.23014.23014.3 0.0826 Jul-52 K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.55 27362 23014 3 1618.970076 540.6625 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4097.2 - 4766.49 - - - 2.6449 - 1.533 0.215 - 58.4 1 2 0 0.0043 14 0 0 0 2.37E+06 1.53E+06 - - - 2.0712 0.9931 230117_WJC_METTL3_WT_vs_EV_F03.23024.23024.3 0.0342 Jun-52 K.ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1626.98 1.56 27366 23024 3 1626.985211 543.3339 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4098.6 - 42686.5 - - - 3.2066 - 1.325 0.262 - 51.6 1 2 0 0.0052 14 0 0 0 2.44E+06 1.57E+06 - - - 2.2075 0.9994 230117_WJC_METTL3_WT_vs_EV_F03.23025.23025.2 3.07E-05 24-Aug K.SLEEIYLFSLPIK[136.11].E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN,tr|H3BNG3|H3BNG3_HUMAN,tr|H0YE27|H0YE27_HUMAN" 7 1558.8738 0.02 27367 23025 2 1558.878917 780.4442 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.53 4098.8 - 13113.1 - - - 3.2844 - 1.662 0.544 - 164.6 1 2 0 0.0051 13 0 0 0 7.76E+03 5.15E+05 - - - 4.3612 0.9988 230117_WJC_METTL3_WT_vs_EV_F03.23122.23122.2 0.0419 28-Aug R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 10.32 27371 23122 2 1581.915813 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4117.3 - 6971.67 - - - 4.3024 - 2.014 0.472 - 173.4 1 2 0 0.0068 15 0 0 0 5.41E+06 5.24E+05 - - - 4.2463 0.9993 230117_WJC_METTL3_WT_vs_EV_F03.23161.23161.2 0.000453 16-Aug R.IAIYELLFK[136.11].E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1116.6674 1.48 27380 23161 2 1116.670452 559.341 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4123.7 - 59489.4 - - - 2.7036 - 1.829 0.358 - 172.4 1 2 0 0.003 9 0 0 0 4.98E+06 3.36E+06 - - - 3.431 1 230117_WJC_METTL3_WT_vs_EV_F03.23204.23204.2 3.13E-08 16/32 R.AQLGVQAFADALLIIPK.V sp|P40227|TCPZ_HUMAN 1 1767.0295 2.83 27383 23204 2 1767.043227 884.522 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.88 4131.8 - 225305 - - - 7.7927 - 3.527 0.659 - 539.3 1 2 0 0.0138 17 0 0 0 4.38E+05 1.55E+05 - - - 7.0029 0.9627 230117_WJC_METTL3_WT_vs_EV_F03.23510.23510.2 2.03 16-Apr R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.49 27400 23510 2 1108.655845 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4190.8 - 158904 - - - 2.356 - 1.032 0.102 - 41.6 2 2 0 0.0026 9 0 0 0 2.66E+06 1.79E+06 - - - -0.2498 0.978 230117_WJC_METTL3_WT_vs_EV_F04.03494.03494.2 0.299 12-Sep K.HPELADK.N "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 808.4079 1.44 27421 3494 2 808.404537 405.2112 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 5.32 1377.6 - 196650 - - - -4.1823 - 1.639 0.226 - 258.8 1 2 0 -0.0034 7 0 0 0 9.06E+06 6.29E+06 - - - 2.2747 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.04129.04129.2 0.0217 12-Aug R.NSTIPTK.Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 759.4127 9.22 27440 4129 2 759.412456 380.7136 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 1489.9 - 540895 - - - -0.2805 - 1.715 0.319 - 286.9 1 2 0 -0.0002 7 0 0 0 2.15E+07 2.33E+06 - - - 3.1062 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.04159.04159.2 0.459 12-Jul R.FTDEESR[166.11].V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 892.3802 0.7 27442 4159 2 892.380125 447.1974 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1495.2 - 977498 - - - -0.0796 - 1.317 0.288 - 156.1 1 2 0 -0.0001 7 0 0 0 1.81E+07 2.56E+07 - - - 2.0406 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.04161.04161.2 0.00555 18-Nov R.IAGQVAAANK.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 941.5294 1.55 27443 4161 2 941.528691 471.772 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1495.4 - 122182 - - - -0.7849 - 2.206 0.365 - 359.9 1 2 0 -0.0007 10 0 0 0 1.17E+07 7.54E+06 - - - 3.9451 0.9596 230117_WJC_METTL3_WT_vs_EV_F04.04230.04230.2 0.184 14-Jun R.NTEEEGLK[136.11].Y "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 926.4436 1.35 27446 4230 2 926.440811 464.2291 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.25 1507.4 - 359196 - - - -3.0547 - 1.196 0.207 - 156.6 1 2 0 -0.0028 8 0 0 0 2.82E+07 2.09E+07 - - - 1.1088 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.04262.04262.2 0.086 12-Jul R.EAQVNVR[166.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 824.438 0.05 27447 4262 2 824.437436 413.2263 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1513 - 685037 - - - -0.6671 - 1.418 0.253 - 341.1 1 2 0 -0.0006 7 0 0 0 1.36E+07 2.86E+08 - - - 2.0161 0.9547 230117_WJC_METTL3_WT_vs_EV_F04.04265.04265.2 0.751 12-May R.EAQVNVR.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 814.4297 0.05 27448 4265 2 814.428489 408.2221 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1513.4 - 529257 - - - -1.5066 - 1.048 0.153 - 145.7 1 2 0 -0.0012 7 0 0 0 1.34E+07 2.61E+08 - - - 0.3192 0.9933 230117_WJC_METTL3_WT_vs_EV_F04.04329.04329.2 0.0936 12-Jun K.HTLTQIK.D sp|P40227|TCPZ_HUMAN 1 839.4865 18.05 27451 4329 2 839.485141 420.7505 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 8.76 1524.5 - 198685 - - - -1.6212 - 1.241 0.321 - 79.5 3 2 0 -0.0014 7 0 0 0 7.32E+06 4.05E+05 - - - 1.8825 0.8939 230117_WJC_METTL3_WT_vs_EV_F04.04496.04496.3 1.94 Jun-36 R.KQDSGHLDLR.N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1167.5996 3.73 27459 4496 3 1167.599197 390.2072 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1553.2 - 6.43E+06 - - - -0.3751 - 1.125 0.141 - 15.7 2 2 0 -0.0004 10 0 0 0 1.50E+07 4.02E+06 - - - 0.3165 0.986 230117_WJC_METTL3_WT_vs_EV_F04.04541.04541.2 1.52 16-May K.VLENAEGAR.T "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 957.488 9.12 27463 4541 2 957.48837 479.7513 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.53 1560.7 - 198034 - - - 0.4292 - 1.176 0.134 - 84.6 2 2 0 0.0004 9 0 0 0 4.78E+06 5.24E+05 - - - 0.3651 0.9347 230117_WJC_METTL3_WT_vs_EV_F04.04942.04942.2 0.819 14-Apr R.TSIEVGVK.G sp|Q03052|PO3F1_HUMAN 1 831.4702 999 27465 4942 2 831.472047 416.7424 "POU domain, class 3, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU3F1 PE=2 SV=3" 5.66 1633.6 - 2.51E+06 - - - 2.2418 - 0.915 0.133 - 46.6 8 2 0 0.0019 8 0 0 0 2.03E+09 0.00E+00 - - - -0.6486 0.8965 230117_WJC_METTL3_WT_vs_EV_F04.05050.05050.2 0.45 16-Sep K.TIAPQNAPR[166.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 976.5329 0.11 27468 5050 2 976.528646 489.2738 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1652.9 - 534695 - - - -4.4064 - 1.576 0.085 - 191 1 2 0 -0.0043 9 0 0 0 2.67E+07 2.40E+08 - - - 0.9835 0.9799 230117_WJC_METTL3_WT_vs_EV_F04.05151.05151.2 0.56 12-Jun K.LVEESVK[136.11].H "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 810.4578 0.26 27470 5151 2 810.456551 406.2362 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 1670.5 - 393814 - - - -1.5831 - 1.32 0.139 - 129 1 2 0 -0.0013 7 0 0 0 5.14E+06 2.01E+07 - - - 0.9469 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.05346.05346.2 0.127 12-Jun K.MYEEHLK[136.11].R "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 956.4517 0.67 27478 5346 2 956.452575 479.2331 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.38 1704.6 - 228878 - - - 0.9117 - 1.139 0.216 - 151.5 1 2 0 0.0009 7 0 0 0 7.12E+06 1.06E+07 - - - 1.0485 0.9916 230117_WJC_METTL3_WT_vs_EV_F04.05516.05516.2 0.00219 14-Sep K.EHC[160.03]LVGVK.G sp|Q86U44|MTA70_HUMAN 1 940.48 68.57 27486 5516 2 940.485967 471.2473 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 1735.5 - 895521 - - - 6.3053 - 1.61 0.372 - 401.4 1 2 0 0.0059 8 0 0 0 6.54E+07 9.53E+05 - - - 3.223 0.9908 230117_WJC_METTL3_WT_vs_EV_F04.05531.05531.2 2.18 12-Jul K.ITITNDK.G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 803.4389 12.1 27487 5531 2 803.43971 402.7267 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1738.2 - 693134 - - - 1.0293 - 1.413 0.055 - 187.6 1 2 0 0.0008 7 0 0 0 1.17E+08 9.66E+06 - - - 0.5424 0.9884 230117_WJC_METTL3_WT_vs_EV_F04.05538.05538.2 0.588 12-Jun K.ITITNDK[136.11].G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 811.4531 12.1 27488 5538 2 811.456686 406.7338 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1739.3 - 89148.9 - - - 4.4402 - 1.182 0.267 - 114 1 2 0 0.0036 7 0 0 0 1.17E+08 9.66E+06 - - - 1.5417 0.9815 230117_WJC_METTL3_WT_vs_EV_F04.05887.05887.2 0.955 12-Jun K.LAEPYGK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 776.4069 1.43 27496 5887 2 776.408623 389.2107 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1802.4 - 205333 - - - 2.2772 - 1.15 0.096 - 150.7 1 2 0 0.0018 7 0 0 0 1.64E+07 1.15E+07 - - - 0.1923 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.06055.06055.2 0.00672 16-Aug R.VNGSLAVSR[166.11].A "sp|O75688|PPM1B_HUMAN,sp|P35813|PPM1A_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 5 911.5064 0.08 27501 6055 2 911.505555 456.7605 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 9.72 1831.6 - 274045 - - - -0.927 - 1.627 0.355 - 210.6 1 2 0 -0.0008 9 0 0 0 4.58E+05 5.50E+06 - - - 3.0709 0.9788 230117_WJC_METTL3_WT_vs_EV_F04.06060.06060.2 0.126 18-Aug K.GSAITGPVAK[136.11].E "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 907.5218 1.84 27502 6060 2 907.520445 454.7682 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.75 1832.3 - 156300 - - - -1.5283 - 1.134 0.202 - 174.1 1 2 0 -0.0014 10 0 0 0 1.38E+07 7.50E+06 - - - 0.8835 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.06241.06241.2 0.00384 16-Sep R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 2.13 27507 6241 2 969.513175 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1865.8 - 312403 - - - 1.3368 - 1.8 0.393 - 309.8 1 2 0 0.0013 9 0 0 0 6.91E+07 3.25E+07 - - - 3.6438 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.06910.06910.2 0.0259 24-Jul K.GPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1199.6146 999 27533 6910 2 1199.61641 600.8146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1984.5 - 65655.9 - - - 1.4955 - 1.543 0.387 - 141.9 1 2 0 0.0018 13 0 0 0 7.33E+06 0.00E+00 - - - 3.012 0.99 230117_WJC_METTL3_WT_vs_EV_F04.06937.06937.2 0.361 12-May K.IIAPPER[166.11].K "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 12 804.4733 0.66 27536 6937 2 804.473908 403.2439 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 1989 - 180630 - - - 0.7458 - 0.991 0.205 - 95.8 1 2 0 0.0006 7 0 0 0 2.88E+07 4.36E+07 - - - 0.5263 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.06942.06942.2 0.203 12-Jun R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 339.5 27537 6942 2 776.383419 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1989.8 - 801814 - - - 2.2103 - 1.352 0.188 - 143.3 1 2 0 0.0017 7 0 0 0 4.94E+09 1.46E+07 - - - 1.3846 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.07039.07039.2 0.00644 16-Aug K.SAAMTLNER[166.11].F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1001.484 0.85 27542 7039 2 1001.485861 501.7493 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 2006.7 - 155621 - - - 1.9082 - 1.568 0.407 - 226.4 1 2 0 0.0019 9 0 0 0 1.63E+07 1.91E+07 - - - 3.3478 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.07146.07146.2 0.171 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 1.01 27547 7146 2 776.38208 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2025.4 - 395841 - - - 0.4856 - 1.471 0.22 - 181.8 1 2 0 0.0004 7 0 0 0 8.65E+07 8.54E+07 - - - 1.8887 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.07178.07178.2 0.0037 14-Aug K.GANPVEIR.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 854.461 1.87 27548 7178 2 854.461017 428.2378 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 2031.2 - 420377 - - - 0.0012 - 1.577 0.313 - 266.3 1 2 0 0 8 0 0 0 5.67E+07 3.04E+07 - - - 2.7267 0.9854 230117_WJC_METTL3_WT_vs_EV_F04.07211.07211.2 0.348 12-Jul R.IGVITNR[166.11].E sp|P62701|RS4X_HUMAN 1 781.4686 0.87 27552 7211 2 781.468915 391.7416 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2036.7 - 452404 - - - 0.4581 - 1.503 0 - 160.7 1 2 0 0.0004 7 0 0 0 1.82E+07 2.10E+07 - - - 0.332 0.9951 230117_WJC_METTL3_WT_vs_EV_F04.07217.07217.2 0.028 14-Jul K.GANPVEIR[166.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 864.4693 1.88 27553 7217 2 864.4693 433.2419 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 2037.7 - 457501 - - - 0.0162 - 1.101 0.265 - 205.2 1 2 0 0 8 0 0 0 5.68E+07 3.02E+07 - - - 1.2885 0.9896 230117_WJC_METTL3_WT_vs_EV_F04.07256.07256.2 0.49 14-Jun K.VGEVIVTK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.5208 2.01 27556 7256 2 851.522721 426.7677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2044.5 - 133732 - - - 2.2924 - 1.353 0.116 - 100.4 3 2 0 0.002 8 0 0 0 1.07E+08 5.31E+07 - - - 0.5958 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.07271.07271.2 0.0163 14-Oct K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 2.01 27557 7271 2 843.508172 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2047.4 - 757929 - - - 1.9004 - 2.088 0.352 - 292.4 1 2 0 0.0016 8 0 0 0 1.07E+08 5.31E+07 - - - 3.8607 0.9496 230117_WJC_METTL3_WT_vs_EV_F04.07546.07546.2 0.532 16-Jul K.VTMQNLNDR.L "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 8 1089.5237 999 27570 7546 2 1089.523111 545.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.81 2095.5 - 176179 - - - -0.5333 - 1.224 0.029 - 129.8 1 2 0 -0.0006 9 0 0 0 6.51E+06 0.00E+00 - - - -0.1602 0.9054 230117_WJC_METTL3_WT_vs_EV_F04.07611.07611.2 8.39 12-May K.EVSTYIK.K "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 838.4436 2.52 27576 7611 2 838.4456 420.2291 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.1 2106.7 - 268518 - - - 2.3448 - 0.877 0.087 - 123 2 2 0 0.002 7 0 0 0 1.64E+07 6.51E+06 - - - -0.8674 0.997 230117_WJC_METTL3_WT_vs_EV_F04.07689.07689.2 0.0698 16-Jun R.VLNTNIDGR[166.11].R "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1010.5384 1.74 27585 7689 2 1010.540228 506.2765 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.81 2119.6 - 132739 - - - 1.7812 - 1.201 0.248 - 87.5 1 2 0 0.0018 9 0 0 0 2.69E+07 1.54E+07 - - - 1.402 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.07698.07698.2 0.0102 16-Jul R.VLNTNIDGR.R "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1000.5302 1.75 27587 7698 2 1000.53018 501.2724 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.81 2121 - 225800 - - - 0.022 - 1.432 0.353 - 222.5 1 2 0 0 9 0 0 0 2.69E+07 1.54E+07 - - - 2.6871 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.07707.07707.2 0.125 14-Jul R.VLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 815.4753 0.92 27589 7707 2 815.474999 408.7449 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 2122.3 - 607265 - - - -0.3311 - 1.43 0.329 - 214 1 2 0 -0.0003 8 0 0 0 2.84E+07 3.10E+07 - - - 2.5496 0.9925 230117_WJC_METTL3_WT_vs_EV_F04.07756.07756.2 0.235 16-May K.DVDGAYMTK.V sp|P04264|K2C1_HUMAN 1 998.4379 13.4 27594 7756 2 998.438673 500.2262 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.21 2130.5 - 125718 - - - 0.7772 - 0.911 0.265 - 57.2 1 2 0 0.0008 9 0 0 0 6.90E+06 5.15E+05 - - - 0.7284 0.9951 230117_WJC_METTL3_WT_vs_EV_F04.07778.07778.2 0.554 14-Jul R.FSELTAEK.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 923.46 6.92 27598 7778 2 923.461461 462.7373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2134 - 473710 - - - 1.568 - 1.175 0.199 - 85.5 1 2 0 0.0014 8 0 0 0 3.27E+07 4.72E+06 - - - 0.9967 0.9686 230117_WJC_METTL3_WT_vs_EV_F04.07798.07798.2 22.2 12-Jun R.IPPVAVR[166.11].L "sp|Q14839|CHD4_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A0G2JM70|A0A0G2JM70_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|V9GYG6|V9GYG6_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 760.4835 0.001 27602 7798 2 760.483914 381.249 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 2137.2 - 466089 - - - 0.572 - 1.066 0.103 - 124.8 3 2 0 0.0004 7 0 0 0 0.00E+00 1.37E+08 - - - -0.209 0.9314 230117_WJC_METTL3_WT_vs_EV_F04.07860.07860.2 7.2 12-Apr R.EIAQDFK.T "sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 9 849.4232 0.74 27607 7860 2 849.42401 425.7189 Histone H3.1t OS=Homo sapiens OX=9606 GN=H3-4 PE=1 SV=3 4.37 2147.8 - 146592 - - - 0.9147 - 0.962 0.041 - 53.1 1 2 0 0.0008 7 0 0 0 9.44E+06 1.28E+07 - - - -0.7792 0.9725 230117_WJC_METTL3_WT_vs_EV_F04.07864.07864.2 3.53E-05 16-Oct Y.PDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 953.5546 999 27608 7864 2 953.556962 477.7846 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2148.4 - 488846 - - - 2.4959 - 2.137 0.443 - 356.6 1 1 0 0.0024 9 0 0 0 2.86E+07 0.00E+00 - - - 4.5092 0.8875 230117_WJC_METTL3_WT_vs_EV_F04.07878.07878.2 0.828 12-Jun D.VIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 784.4807 9.27 27611 7878 2 784.481214 393.2476 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 2150.6 - 490880 - - - 0.6692 - 1.352 0.274 - 184 1 1 0 0.0005 7 0 0 0 6.46E+07 6.97E+06 - - - 2.0202 1 230117_WJC_METTL3_WT_vs_EV_F04.07882.07882.2 0.00237 13/18 R.YPDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 1116.6179 855.26 27612 7882 2 1116.618874 559.3162 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2151.2 - 1.17E+06 - - - 0.8633 - 2.04 0.563 - 562.1 1 2 0 0.001 10 0 0 0 7.18E+07 8.39E+04 - - - 5.1891 0.9871 230117_WJC_METTL3_WT_vs_EV_F04.07954.07954.2 1.91 14-Jun K.HVVFIAQR.R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 968.5556 11.07 27616 7954 2 968.556517 485.2851 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 9.76 2163.9 - 103529 - - - 0.9623 - 1.147 0.117 - 161.6 1 2 0 0.0009 8 0 0 0 8.41E+06 7.60E+05 - - - 0.3185 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.07963.07963.2 0.00068 16-Oct R.TLLEGEESR.M sp|P04264|K2C1_HUMAN 1 1032.5088 66.8 27618 7963 2 1032.509588 517.2617 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.25 2165.2 - 940825 - - - 0.8077 - 1.799 0.44 - 369.5 1 2 0 0.0008 9 0 0 0 3.92E+07 5.86E+05 - - - 3.9895 0.9812 230117_WJC_METTL3_WT_vs_EV_F04.07979.07979.2 15.9 12-Jun R.IPPVAVR[166.11].L "sp|Q14839|CHD4_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A0G2JM70|A0A0G2JM70_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|V9GYG6|V9GYG6_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 760.4835 0.001 27622 7979 2 760.48373 381.249 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 2167.6 - 421178 - - - 0.3301 - 1.225 0.069 - 136.8 1 2 0 0.0003 7 0 0 0 0.00E+00 1.37E+08 - - - 0.1936 0.963 230117_WJC_METTL3_WT_vs_EV_F04.07998.07998.3 4.98 Jun-60 K.ATAGDTHLGGEDFDNR.L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1674.7234 33.95 27625 7998 3 1674.726748 559.2484 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2170.7 - 65183.2 - - - 2.0045 - 1.238 0.144 - 23.2 1 2 0 0.0034 16 0 0 0 2.37E+06 6.99E+04 - - - 0.6923 0.9907 230117_WJC_METTL3_WT_vs_EV_F04.08110.08110.2 0.0372 12-Jun R.FC[160.03]ALEEK.C "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 895.411 0.32 27638 8110 2 895.409825 448.7128 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2189.6 - 208038 - - - -1.2609 - 1.226 0.231 - 117.7 1 2 0 -0.0011 7 0 0 0 8.30E+06 2.63E+07 - - - 1.3924 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.08203.08203.2 0.878 14-May K.C[160.03]GEALGLK.Q "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 846.4269 0.56 27645 8203 2 846.428143 424.2207 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.99 2205.7 - 117049 - - - 1.4225 - 1.332 0.186 - 87.8 1 2 0 0.0012 8 0 0 0 1.22E+07 2.16E+07 - - - 1.279 0.8562 230117_WJC_METTL3_WT_vs_EV_F04.08215.08215.2 0.277 16-Jul R.PSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 969.5243 0.7 27648 8215 2 969.525626 485.7694 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.43 2207.5 - 134265 - - - 1.3223 - 1.543 0.186 - 154.3 1 1 0 0.0013 9 0 0 0 8.18E+06 1.18E+07 - - - 1.6692 0.9945 230117_WJC_METTL3_WT_vs_EV_F04.08228.08228.2 0.0439 12-Jun K.VLAAVYK[136.11].A "sp|P05062|ALDOB_HUMAN,sp|P04075|ALDOA_HUMAN,sp|P09972|ALDOC_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|A8MVZ9|A8MVZ9_HUMAN,tr|A0A3B3IS80|A0A3B3IS80_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|A0A087WXX2|A0A087WXX2_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 10 770.4782 1.9 27652 8228 2 770.479082 386.2464 Fructose-bisphosphate aldolase B OS=Homo sapiens OX=9606 GN=ALDOB PE=1 SV=2 8.56 2209.4 - 790862 - - - 1.1759 - 1.3 0.14 - 122.8 1 2 0 0.0009 7 0 0 0 1.65E+08 8.68E+07 - - - 0.9061 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.08243.08243.2 0.252 12-Jun R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 230.31 27653 8243 2 808.433703 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2212.1 - 651160 - - - 0.783 - 1.357 0.288 - 76.8 1 2 0 0.0006 7 0 0 0 1.17E+08 5.10E+05 - - - 2.1353 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.08263.08263.2 0.00049 18-Oct K.LLNTVEETTK[136.11].D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1154.6274 0.18 27655 8263 2 1154.629629 578.321 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2215.5 - 349254 - - - 1.914 - 2.169 0.395 - 289.4 1 2 0 0.0022 10 0 0 0 3.82E+06 2.14E+07 - - - 4.119 0.955 230117_WJC_METTL3_WT_vs_EV_F04.08268.08268.2 4.73 18-Aug K.LLNTVEETTK.D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1146.6132 0.18 27657 8268 2 1146.615791 574.3139 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2216.1 - 651449 - - - 2.2431 - 1.173 0.015 - 143 1 2 0 0.0026 10 0 0 0 3.82E+06 2.14E+07 - - - -0.4036 0.9864 230117_WJC_METTL3_WT_vs_EV_F04.08291.08291.2 0.321 12-Jul K.LVTDLTK.V "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 788.4644 11.54 27660 8291 2 788.46446 395.2395 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.84 2219.9 - 652485 - - - 0.1141 - 1.347 0.068 - 141.3 1 2 0 0.0001 7 0 0 0 2.68E+07 2.33E+06 - - - 0.4871 0.9725 230117_WJC_METTL3_WT_vs_EV_F04.08295.08295.2 0.347 14-Jun R.ILSGVVTK.M "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 815.5117 0.86 27662 8295 2 815.512132 408.7631 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 2220.5 - 299312 - - - 0.5861 - 1.375 0.001 - 87.6 2 2 0 0.0005 8 0 0 0 3.44E+07 3.98E+07 - - - -0.1258 0.9913 230117_WJC_METTL3_WT_vs_EV_F04.08303.08303.2 0.157 14-Jul R.ILSGVVTK[136.11].M "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 823.5259 0.86 27664 8303 2 823.526256 412.7702 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 2221.7 - 585949 - - - 0.4881 - 1.385 0.09 - 115.7 1 2 0 0.0004 8 0 0 0 3.44E+07 3.98E+07 - - - 0.6879 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.08310.08310.2 0.107 14-Aug R.IVVAAVAR[166.11].A "sp|Q7Z2T5|TRM1L_HUMAN,tr|X6RK96|X6RK96_HUMAN" 2 807.5206 1.63 27666 8310 2 807.521224 404.7676 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 9.75 2222.7 - 767267 - - - 0.7814 - 1.531 0.278 - 136.8 1 2 0 0.0006 8 0 0 0 5.59E+07 3.42E+07 - - - 2.3787 0.9965 230117_WJC_METTL3_WT_vs_EV_F04.08357.08357.2 0.00948 18-Jun R.ASAVSELSPR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1025.5381 0.78 27673 8357 2 1025.541043 513.7763 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2230.2 - 147566 - - - 2.8756 - 1.27 0.27 - 54 1 2 0 0.0029 10 0 0 0 9.99E+06 1.28E+07 - - - 1.7015 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.08389.08389.2 0.000205 18-Sep R.ASAVSELSPR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1015.5298 0.78 27678 8389 2 1015.531657 508.7722 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2235.5 - 120034 - - - 1.805 - 1.846 0.296 - 180.5 1 2 0 0.0018 10 0 0 0 9.99E+06 1.28E+07 - - - 2.9378 0.9878 230117_WJC_METTL3_WT_vs_EV_F04.08436.08436.2 3.25 12-Jun R.LLPAEVK[136.11].A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 776.4887 1.35 27680 8436 2 776.48886 389.2516 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6 2243.8 - 2.08E+06 - - - 0.1533 - 1.234 0.132 - 122.6 2 2 0 0.0001 7 0 0 0 2.42E+08 1.80E+08 - - - 0.5477 0.9854 230117_WJC_METTL3_WT_vs_EV_F04.08467.08467.2 2.73 12-Jun K.SEITELR.R "sp|P13645|K1C10_HUMAN,sp|Q8TDM6|DLG5_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 3 846.4447 5.55 27685 8467 2 846.444096 424.2296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2248.7 - 246026 - - - -0.71 - 1.242 0.142 - 225.5 1 2 0 -0.0006 7 0 0 0 1.09E+07 1.96E+06 - - - 0.7763 1 230117_WJC_METTL3_WT_vs_EV_F04.08476.08476.2 9.51E-06 13/20 K.FAEALGSTEAK[136.11].A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1130.5699 0.47 27688 8476 2 1130.571819 566.2922 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2249.9 - 246702 - - - 1.6938 - 2.358 0.531 - 522.1 1 2 0 0.0019 11 0 0 0 6.08E+06 1.29E+07 - - - 5.283 0.9949 230117_WJC_METTL3_WT_vs_EV_F04.08495.08495.2 0.0137 20-Sep K.FAEALGSTEAK.A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1122.5557 0.47 27691 8495 2 1122.56067 562.2851 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2252.9 - 168071 - - - 4.4238 - 1.503 0.291 - 109.9 1 2 0 0.005 11 0 0 0 6.03E+06 1.29E+07 - - - 2.2911 0.9954 230117_WJC_METTL3_WT_vs_EV_F04.08579.08579.2 0.0709 16-Jun R.ILQDSLGGR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 967.5326 0.33 27700 8579 2 967.532949 484.7736 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2266.8 - 62471.6 - - - 0.3462 - 1.276 0.197 - 84.5 1 2 0 0.0003 9 0 0 0 5.79E+06 1.74E+07 - - - 1.2011 0.9918 230117_WJC_METTL3_WT_vs_EV_F04.08613.08613.2 0.237 16-Jul R.ILQDSLGGR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 957.5243 0.33 27707 8613 2 957.524668 479.7694 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2272.2 - 127982 - - - 0.3384 - 1.331 0.123 - 124.7 1 2 0 0.0003 9 0 0 0 5.79E+06 1.73E+07 - - - 0.7766 0.9597 230117_WJC_METTL3_WT_vs_EV_F04.08715.08715.2 9.26 12-Jun R.LLEQGIR.V "sp|P28340|DPOD1_HUMAN,sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 7 827.4865 1.66 27721 8715 2 827.4869 414.7505 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 6 2289.1 - 217647 - - - 0.481 - 1.211 0 - 104 1 2 0 0.0004 7 0 0 0 3.30E+07 1.99E+07 - - - -0.3525 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.08800.08800.2 0.0836 12-Aug K.NIQVVVR[166.11].C "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 836.5108 0.24 27732 8800 2 836.510049 419.2627 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 9.75 2302.6 - 1.11E+06 - - - -0.8464 - 1.422 0.276 - 286.4 1 2 0 -0.0007 7 0 0 0 1.80E+07 7.54E+07 - - - 2.1948 0.9961 230117_WJC_METTL3_WT_vs_EV_F04.08845.08845.2 0.0798 12-Jun R.AMIIAER[166.11].Q "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 812.4454 2.02 27737 8845 2 812.444787 407.23 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.05 2309.8 - 393045 - - - -0.7287 - 1.39 0.24 - 181.7 1 2 0 -0.0006 7 0 0 0 5.79E+07 2.87E+07 - - - 1.8569 0.9269 230117_WJC_METTL3_WT_vs_EV_F04.08868.08868.2 2.34 12-Apr R.LLGWDDR.A sp|Q8WUY1|THEM6_HUMAN 1 873.4345 1024.22 27741 8868 2 873.433403 437.7245 Protein THEM6 OS=Homo sapiens OX=9606 GN=THEM6 PE=1 SV=2 4.21 2313.4 - 1.09E+06 - - - -1.2182 - 0.908 0.171 - 38.2 2 2 0 -0.0011 7 0 0 0 1.07E+08 1.04E+05 - - - -0.1366 0.9862 230117_WJC_METTL3_WT_vs_EV_F04.08873.08873.2 0.148 12-Jul R.AMIIAER.Q "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 802.4371 2.45 27743 8873 2 802.437175 402.2258 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.05 2314 - 877929 - - - 0.0822 - 1.447 0.037 - 200.8 1 2 0 0.0001 7 0 0 0 7.15E+07 2.92E+07 - - - 0.485 0.9883 230117_WJC_METTL3_WT_vs_EV_F04.08912.08912.2 1.51 16-Jul R.NIVEAAAVR[166.11].D "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 951.5377 0.96 27750 8912 2 951.538218 476.7761 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 6 2320.1 - 1.20E+06 - - - 0.5444 - 0.925 0.223 - 136.4 1 2 0 0.0005 9 0 0 0 1.74E+07 1.81E+07 - - - 0.4624 0.9418 230117_WJC_METTL3_WT_vs_EV_F04.08914.08914.2 1.93 12-Jul K.LIVDSVK.E sp|O60216|RAD21_HUMAN 1 772.4695 3.71 27751 8914 2 772.469722 387.242 Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2 5.84 2320.5 - 1.17E+06 - - - 0.3456 - 1.173 0.004 - 162.6 2 2 0 0.0003 7 0 0 0 5.98E+07 1.61E+07 - - - -0.5584 0.9956 230117_WJC_METTL3_WT_vs_EV_F04.08926.08926.2 0.254 14-Jun K.LVIEEAER.S sp|P50991|TCPD_HUMAN 1 957.5131 18.34 27752 8926 2 957.513613 479.7638 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.25 2322.5 - 135371 - - - 0.5243 - 1.261 0.197 - 124 1 2 0 0.0005 8 0 0 0 9.25E+06 5.04E+05 - - - 1.1953 0.9744 230117_WJC_METTL3_WT_vs_EV_F04.08934.08934.2 20.1 12-Jul R.HLQLAIR[166.11].N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 859.5267 0.82 27754 8934 2 859.526928 430.7706 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2323.7 - 332214 - - - 0.2176 - 1.232 0.043 - 177.4 1 2 0 0.0002 7 0 0 0 9.78E+07 1.19E+08 - - - 0.0196 0.9858 230117_WJC_METTL3_WT_vs_EV_F04.08937.08937.2 1.65 12-Jun K.LIETVVK[136.11].Q "sp|Q8TAG9|EXOC6_HUMAN,tr|E7EW84|E7EW84_HUMAN" 2 808.515 1.83 27755 8937 2 808.515972 405.2648 Exocyst complex component 6 OS=Homo sapiens OX=9606 GN=EXOC6 PE=1 SV=3 6 2324.1 - 182065 - - - 1.2579 - 1.143 0.104 - 72.4 1 2 0 0.001 7 0 0 0 1.50E+07 8.21E+06 - - - 0.2323 0.9903 230117_WJC_METTL3_WT_vs_EV_F04.08969.08969.2 1.47 12-Jul K.IIDAALR[166.11].A "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 780.4733 2.25 27758 8969 2 780.472266 391.2439 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2329.4 - 831950 - - - -1.3351 - 1.403 0.175 - 137.7 1 2 0 -0.001 7 0 0 0 2.21E+09 9.81E+08 - - - 1.4061 0.9844 230117_WJC_METTL3_WT_vs_EV_F04.08973.08973.2 13.4 12-Aug K.IIDAALR.A "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 770.465 2.25 27759 8973 2 770.464176 386.2398 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2330 - 1.88E+06 - - - -1.1188 - 1.349 0.126 - 203.3 1 2 0 -0.0009 7 0 0 0 2.20E+09 9.80E+08 - - - 0.9199 0.9307 230117_WJC_METTL3_WT_vs_EV_F04.09083.09083.3 0.0215 Oct-36 R.LKYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1233.6717 1.6 27771 9083 3 1233.669881 412.2312 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2348 - 670164 - - - -1.5045 - 1.873 0.352 - 143.1 1 2 1 -0.0019 10 0 0 0 4.26E+07 2.67E+07 - - - 4.2966 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.09135.09135.2 0.648 12-May R.LVGEIVR[166.11].R "sp|Q13232|NDK3_HUMAN,sp|Q15021|CND1_HUMAN,sp|Q3MIP1|IPIL2_HUMAN,tr|H3BRA8|H3BRA8_HUMAN,tr|H3BMQ7|H3BMQ7_HUMAN,tr|H3BPD9|H3BPD9_HUMAN,tr|E7EN77|E7EN77_HUMAN" 7 794.489 1.82 27778 9135 2 794.48912 398.2518 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6 2356.2 - 995052 - - - 0.2026 - 1.38 0.179 - 86.4 2 2 0 0.0002 7 0 0 0 6.83E+08 3.76E+08 - - - 1.2491 0.9715 230117_WJC_METTL3_WT_vs_EV_F04.09224.09224.2 1.05 12-Jun R.DLAENIR.K tr|A0A0C4DGZ7|A0A0C4DGZ7_HUMAN 1 829.4294 2.45 27791 9224 2 829.427354 415.722 Ankyrin repeat and death domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ANKDD1A PE=4 SV=1 4.37 2370.7 - 240768 - - - -2.4438 - 1.242 0.185 - 146.4 1 2 0 -0.002 7 0 0 0 2.72E+07 1.11E+07 - - - 1.0935 0.9562 230117_WJC_METTL3_WT_vs_EV_F04.09287.09287.2 1.65 14-May R.TTC[160.03]FQGVK.V "sp|Q86XD8|ZFAN4_HUMAN,tr|J3KPC0|J3KPC0_HUMAN" 2 939.4484 5.49 27801 9287 2 939.450904 470.7315 AN1-type zinc finger protein 4 OS=Homo sapiens OX=9606 GN=ZFAND4 PE=2 SV=2 7.89 2380.8 - 73351.1 - - - 2.6633 - 1.026 0.085 - 77.1 1 2 0 0.0025 8 0 0 0 6.09E+07 1.11E+07 - - - -0.2546 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.09312.09312.2 0.168 14-Aug K.VIPELNGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 868.5018 3.04 27804 9312 2 868.502692 435.2582 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2385 - 1.17E+06 - - - 1.0063 - 1.193 0.266 - 235 1 2 0 0.0009 8 0 0 0 9.25E+07 3.04E+07 - - - 1.5376 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.09320.09320.2 0.00302 16-Aug R.QTVAVGVIK.N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 913.5597 4.25 27807 9320 2 913.560812 457.7871 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2386.1 - 1.10E+06 - - - 1.2533 - 1.581 0.354 - 265 1 2 0 0.0011 9 0 0 0 6.11E+07 1.44E+07 - - - 2.9805 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.09326.09326.2 0.00131 16-Sep R.QTVAVGVIK[136.11].N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 921.5739 4.25 27809 9326 2 921.575034 461.7942 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2386.9 - 398439 - - - 1.2663 - 1.421 0.364 - 246.1 1 2 0 0.0012 9 0 0 0 6.11E+07 1.44E+07 - - - 2.7456 0.9886 230117_WJC_METTL3_WT_vs_EV_F04.09344.09344.2 1.26 12-Jun K.VITTVLK[136.11].F "sp|Q13439|GOGA4_HUMAN,tr|H0Y6I0|H0Y6I0_HUMAN" 2 780.52 1.91 27813 9344 2 780.52075 391.2673 Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4 PE=1 SV=1 8.72 2389.8 - 561451 - - - 0.9084 - 1.152 0.143 - 88.5 2 2 0 0.0007 7 0 0 0 3.94E+07 2.06E+07 - - - 0.4109 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.09353.09353.2 0.0322 14-Jul R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 1.19 27817 9353 2 898.524756 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 2391 - 454874 - - - 1.2687 - 1.376 0.338 - 141.1 1 2 0 0.0011 8 0 0 0 5.61E+07 4.72E+07 - - - 2.4997 0.9908 230117_WJC_METTL3_WT_vs_EV_F04.09358.09358.2 0.795 12-Jun K.VVPLYGR.G "sp|Q99942|RNF5_HUMAN,tr|A0A140TA09|A0A140TA09_HUMAN" 2 802.4701 2.59 27818 9358 2 802.472089 402.2423 E3 ubiquitin-protein ligase RNF5 OS=Homo sapiens OX=9606 GN=RNF5 PE=1 SV=1 8.72 2391.7 - 894197 - - - 2.4487 - 1.066 0.203 - 213.1 1 2 0 0.002 7 0 0 0 8.60E+07 3.31E+07 - - - 0.7423 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.09373.09373.2 0.323 14-Aug R.LVGDVIQR[166.11].F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 908.5319 1.15 27820 9373 2 908.533083 455.2732 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 2394.2 - 993707 - - - 1.3175 - 1.567 0.191 - 189.5 1 2 0 0.0012 8 0 0 0 5.55E+07 4.85E+07 - - - 1.806 0.8516 230117_WJC_METTL3_WT_vs_EV_F04.09428.09428.2 0.00685 14-Jul R.YPDGIISK.P sp|Q86U44|MTA70_HUMAN 1 891.4702 109.01 27833 9428 2 891.471999 446.7424 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2402.7 - 1.34E+06 - - - 2.0371 - 1.458 0.212 - 151.5 1 1 0 0.0018 8 0 0 0 3.70E+08 3.39E+06 - - - 1.7435 0.9746 230117_WJC_METTL3_WT_vs_EV_F04.09485.09485.2 0.211 12-Jun R.IVTTYIR[166.11].E "sp|P50570|DYN2_HUMAN,tr|K7EMQ3|K7EMQ3_HUMAN" 2 874.5152 1.52 27843 9485 2 874.51533 438.2649 Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2 8.75 2411.8 - 316641 - - - 0.1795 - 1.227 0.047 - 104 1 2 0 0.0002 7 0 0 0 2.22E+07 1.46E+07 - - - 0.0363 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.09489.09489.2 0.369 12-Jul K.LLEQALK.T sp|Q99543|DNJC2_HUMAN 1 813.496 1.28 27844 9489 2 813.497372 407.7553 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 6 2412.4 - 307665 - - - 1.6816 - 1.645 0.071 - 134.2 1 2 0 0.0014 7 0 0 0 1.16E+07 9.05E+06 - - - 1.1421 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.09522.09522.2 0.028 18-Jul R.GYSFTTTAER.E "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1131.5197 1.23 27851 9522 2 1131.520095 566.7671 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 2417.4 - 108785 - - - 0.3906 - 1.398 0.325 - 165.8 1 2 0 0.0004 10 0 0 0 5.43E+06 4.42E+06 - - - 2.3765 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.09528.09528.2 0.118 14-Jul R.LVTTGVLK.Q sp|P07305|H10_HUMAN 1 829.5273 1.06 27855 9528 2 829.527352 415.7709 Histone H1.0 OS=Homo sapiens OX=9606 GN=H1-0 PE=1 SV=3 8.75 2418.1 - 506257 - - - 0.0579 - 1.658 0.231 - 199.7 1 2 0 0 8 0 0 0 2.20E+07 2.08E+07 - - - 2.2721 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.09538.09538.2 0.014 18-Aug K.FADLSEAANR.N "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1092.52 1.51 27857 9538 2 1092.523207 547.2673 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 2419.7 - 106304 - - - 2.9473 - 1.701 0.382 - 222.5 1 2 0 0.0032 10 0 0 0 2.34E+07 1.55E+07 - - - 3.3442 0.9835 230117_WJC_METTL3_WT_vs_EV_F04.09561.09561.2 3.02 12-Jul R.LGLVDTR.Q sp|Q6P4I2|WDR73_HUMAN 1 772.4443 7.41 27861 9561 2 772.446601 387.2294 WD repeat-containing protein 73 OS=Homo sapiens OX=9606 GN=WDR73 PE=1 SV=1 5.84 2423.3 - 712566 - - - 2.975 - 1.244 0.108 - 115.1 1 2 0 0.0023 7 0 0 0 1.19E+07 1.60E+06 - - - 0.5298 0.9787 230117_WJC_METTL3_WT_vs_EV_F04.09587.09587.2 1.08 12-May K.LLPYAER[166.11].L "sp|Q14997|PSME4_HUMAN,tr|F8WBH5|F8WBH5_HUMAN" 2 870.4839 1.46 27868 9587 2 870.486188 436.2492 Proteasome activator complex subunit 4 OS=Homo sapiens OX=9606 GN=PSME4 PE=1 SV=2 6 2427.5 - 90377.3 - - - 2.6594 - 1.006 0.158 - 74.1 1 2 0 0.0023 7 0 0 0 8.04E+06 5.51E+06 - - - 0.2262 0.9679 230117_WJC_METTL3_WT_vs_EV_F04.09644.09644.2 3.61 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 119.75 27879 9644 2 841.502203 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 2436.6 - 5.98E+06 - - - 0.0606 - 1.332 0.02 - 193.3 2 2 0 0.0001 8 0 0 0 6.63E+08 5.53E+06 - - - -0.0811 0.9687 230117_WJC_METTL3_WT_vs_EV_F04.09648.09648.2 1.95 12-Jun K.LEPVPLK.G "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN" 2 794.4902 2.66 27881 9648 2 794.489991 398.2524 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6 2437.1 - 637638 - - - -0.2517 - 1.181 0.065 - 158.9 1 2 0 -0.0002 7 0 0 0 5.87E+07 2.21E+07 - - - 0.0482 0.9848 230117_WJC_METTL3_WT_vs_EV_F04.09651.09651.2 4.53 14-Jun R.LLTGPVVR[166.11].G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 863.5468 2.49 27882 9651 2 863.547074 432.7807 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2437.5 - 219119 - - - 0.308 - 1.215 0.115 - 53.6 2 2 0 0.0003 8 0 0 0 3.62E+07 1.45E+07 - - - 0.3432 0.9912 230117_WJC_METTL3_WT_vs_EV_F04.09656.09656.2 7.57 14-Jun R.LLTGPVVR.G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 853.5385 2.49 27885 9656 2 853.538675 427.7765 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2438.2 - 364994 - - - 0.1605 - 1.379 0.104 - 103.3 1 2 0 0.0001 8 0 0 0 3.62E+07 1.45E+07 - - - 0.7783 0.9702 230117_WJC_METTL3_WT_vs_EV_F04.09671.09671.2 2.98 12-Jun K.LEPVPLK[136.11].G "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN" 2 802.5044 2.48 27887 9671 2 802.504693 402.2595 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6 2440.7 - 557594 - - - 0.3763 - 1.123 0.081 - 148.9 2 2 0 0.0003 7 0 0 0 5.47E+07 2.21E+07 - - - -0.1277 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.09682.09682.2 0.0191 14-Jun K.ALVAYYQK[136.11].Y "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 962.5317 3.34 27890 9682 2 962.533547 482.2731 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.54 2442.2 - 80650.5 - - - 1.9521 - 1.234 0.259 - 115.3 1 2 0 0.0019 8 0 0 0 2.61E+07 7.82E+06 - - - 1.5875 0.989 230117_WJC_METTL3_WT_vs_EV_F04.09687.09687.2 0.929 12-Jun R.ILVDVEK.V sp|P11216|PYGB_HUMAN 1 814.48 0.29 27892 9687 2 814.480496 408.2473 "Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB PE=1 SV=5" 4.37 2443 - 617013 - - - 0.5844 - 1.289 0.088 - 107.4 1 2 0 0.0005 7 0 0 0 1.21E+07 4.16E+07 - - - 0.4952 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.09697.09697.3 0.000339 Dec-40 R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 1.24 27895 9697 3 1240.608394 414.5431 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2444.4 - 281135 - - - 0.6642 - 2.142 0.393 - 126.5 1 2 0 0.0008 11 0 0 0 2.29E+07 1.84E+07 - - - 5.0853 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.09710.09710.2 0.00159 28-Jun K.AIADTGANVVVTGGK.V "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1371.7358 87.49 27897 9710 2 1371.737395 686.8752 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.88 2446.4 - 108206 - - - 1.1671 - 1.454 0.292 - 34.8 5 2 0 0.0016 15 0 0 0 1.90E+06 2.17E+04 - - - 1.8053 0.995 230117_WJC_METTL3_WT_vs_EV_F04.09742.09742.2 2.01 12-Jun R.VLSSLVR.D sp|Q969H6|POP5_HUMAN 1 772.4807 1.86 27904 9742 2 772.48173 387.2476 Ribonuclease P\MRP protein subunit POP5 OS=Homo sapiens OX=9606 GN=POP5 PE=1 SV=1 9.72 2451.5 - 504142 - - - 1.3476 - 1.4 0.118 - 169.7 1 2 0 0.001 7 0 0 0 4.39E+07 2.36E+07 - - - 0.9784 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.09760.09760.2 0.0474 22-Jul R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 94.03 27908 9760 2 1380.641027 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2454.3 - 41873.4 - - - 0.0992 - 1.261 0.296 - 123.4 1 2 0 0.0001 12 0 0 0 6.95E+06 7.39E+04 - - - 1.8374 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.09767.09767.2 0.0167 16-Aug K.IVVVTAGVR[166.11].Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 922.5839 0.83 27910 9767 2 922.584193 462.2992 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2455.5 - 506819 - - - 0.2937 - 1.661 0.23 - 211.8 1 2 0 0.0003 9 0 0 0 1.39E+08 1.69E+08 - - - 2.2077 0.9657 230117_WJC_METTL3_WT_vs_EV_F04.09779.09779.2 3.46 12-May K.LEATMLR[166.11].L "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 842.4559 11.81 27913 9779 2 842.456926 422.2352 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6 2457.3 - 311405 - - - 1.1656 - 1.139 0.027 - 54.6 1 2 0 0.001 7 0 0 0 2.56E+08 2.17E+07 - - - -0.3475 0.9958 230117_WJC_METTL3_WT_vs_EV_F04.09782.09782.2 0.471 14-Jul R.ILADEALK.L sp|Q08426|ECHP_HUMAN 1 871.5015 1.21 27914 9782 2 871.502671 436.758 Peroxisomal bifunctional enzyme OS=Homo sapiens OX=9606 GN=EHHADH PE=1 SV=3 4.37 2457.7 - 269097 - - - 1.362 - 1.219 0.198 - 88.7 1 2 0 0.0012 8 0 0 0 7.59E+06 6.28E+06 - - - 1.1003 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.09787.09787.2 0.00446 16-Aug K.IVVVTAGVR.Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 912.5757 0.82 27916 9787 2 912.576007 457.2951 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2458.3 - 1.60E+06 - - - 0.389 - 1.683 0.357 - 217.2 1 2 0 0.0004 9 0 0 0 1.38E+08 1.68E+08 - - - 3.1837 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.09788.09788.2 0.29 12-Jul K.LEATMLR.L "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 832.4477 1.14 27917 9788 2 832.448076 417.2311 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6 2458.4 - 481869 - - - 0.4829 - 1.451 0.14 - 169.9 1 2 0 0.0004 7 0 0 0 1.88E+07 1.64E+07 - - - 1.2544 0.966 230117_WJC_METTL3_WT_vs_EV_F04.09806.09806.2 8.24 12-Jun K.ILLSPER[166.11].V "sp|P24928|RPB1_HUMAN,tr|H3BVE3|H3BVE3_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 3 836.4995 0.95 27922 9806 2 836.499888 419.257 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 6 2461 - 394245 - - - 0.4363 - 1.185 0.026 - 109.5 1 2 0 0.0004 7 0 0 0 8.67E+07 9.11E+07 - - - -0.2292 0.8727 230117_WJC_METTL3_WT_vs_EV_F04.09814.09814.2 0.191 12-Jun N.VDEFVK[136.11]R.L sp|Q9NVH2|INT7_HUMAN 1 899.4956 - 27926 9814 2 899.496593 450.7551 Integrator complex subunit 7 OS=Homo sapiens OX=9606 GN=INTS7 PE=1 SV=1 6.04 2462 - 674072 - - - 1.0851 - 1.401 0.23 - 107 1 1 0 0.001 7 0 0 0 - - - - - 1.8079 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.09818.09818.2 0.00725 18-Nov K.IGAVEEELNR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1138.5858 0.78 27927 9818 2 1138.587992 570.3002 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.25 2462.6 - 159460 - - - 1.9498 - 1.98 0.336 - 417.2 1 2 0 0.0022 10 0 0 0 5.07E+06 6.50E+06 - - - 3.4287 0.8547 230117_WJC_METTL3_WT_vs_EV_F04.09825.09825.2 0.381 12-Aug N.LNTLIQR[166.11].S "sp|P20036|DPA1_HUMAN,sp|Q00839|HNRPU_HUMAN,sp|Q8IUG5|MY18B_HUMAN,tr|A0A140T914|A0A140T914_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|F5H6I8|F5H6I8_HUMAN,tr|A0A140T9R4|A0A140T9R4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A140T9D6|A0A140T9D6_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A140T9Y9|A0A140T9Y9_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A140T9H1|A0A140T9H1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A140T9U4|A0A140T9U4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A140T9F8|A0A140T9F8_HUMAN,tr|J3KQ99|J3KQ99_HUMAN" 24 866.5213 0.54 27929 9825 2 866.52152 434.2679 "HLA class II histocompatibility antigen, DP alpha 1 chain OS=Homo sapiens OX=9606 GN=HLA-DPA1 PE=1 SV=1" 9.75 2463.6 - 1.45E+06 - - - 0.2297 - 1.782 0.14 - 281 1 1 0 0.0002 7 0 0 0 9.01E+07 1.66E+08 - - - 1.9056 0.9887 230117_WJC_METTL3_WT_vs_EV_F04.09830.09830.2 6.29 12-Jun K.ILLSPER.V "sp|P24928|RPB1_HUMAN,tr|H3BVE3|H3BVE3_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 3 826.4913 0.95 27930 9830 2 826.491269 414.2529 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 6 2464.3 - 705707 - - - 0.0194 - 1.266 0.117 - 127.8 1 2 0 0 7 0 0 0 8.77E+07 9.22E+07 - - - 0.6525 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.09854.09854.2 0.0166 18-Jul K.MLVSGAGDIK.L "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 989.5216 54.09 27936 9854 2 989.520938 495.7681 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.59 2467.9 - 202697 - - - -0.6357 - 1.317 0.341 - 128.6 1 2 0 -0.0006 10 0 0 0 1.31E+07 2.42E+05 - - - 2.328 0.993 230117_WJC_METTL3_WT_vs_EV_F04.09892.09892.2 0.305 12-Jul R.MIVGTLK.G "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 760.4517 2.69 27940 9892 2 760.451927 381.2331 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 8.5 2474.1 - 952448 - - - 0.3025 - 1.182 0.18 - 198.5 1 2 0 0.0002 7 0 0 0 3.20E+08 1.19E+08 - - - 0.9002 0.9244 230117_WJC_METTL3_WT_vs_EV_F04.09903.09903.2 2.74 12-Jun R.MIVGTLK[136.11].G "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 768.4659 2.68 27944 9903 2 768.465568 385.2402 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 8.5 2475.5 - 1.10E+06 - - - -0.4281 - 1.147 0.025 - 131.2 2 2 0 -0.0003 7 0 0 0 3.21E+08 1.20E+08 - - - -0.4744 0.9939 230117_WJC_METTL3_WT_vs_EV_F04.09912.09912.2 0.752 12-Jul R.ILLEAAR[166.11].L "sp|P49189|AL9A1_HUMAN,sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 3 794.489 2.03 27948 9912 2 794.488726 398.2518 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3 6 2476.7 - 636066 - - - -0.2933 - 1.432 0.145 - 181.8 1 2 0 -0.0002 7 0 0 0 6.24E+07 3.07E+07 - - - 1.2496 0.9899 230117_WJC_METTL3_WT_vs_EV_F04.09928.09928.2 2.52 12-Jun R.ILLEAAR.L "sp|P49189|AL9A1_HUMAN,sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 3 784.4807 2.03 27952 9928 2 784.481036 393.2476 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3 6 2479.1 - 1.62E+06 - - - 0.4423 - 1.314 0.111 - 95.9 2 2 0 0.0003 7 0 0 0 6.32E+07 3.11E+07 - - - 0.5915 0.894 230117_WJC_METTL3_WT_vs_EV_F04.09978.09978.2 0.00285 18-Jun K.EYSGFAGVSR.P "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1071.4985 0.84 27959 9978 2 1071.499098 536.7565 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.1 2487.2 - 321536 - - - 0.5366 - 1.085 0.387 - 60.2 1 1 0 0.0006 10 0 0 0 5.87E+06 7.00E+06 - - - 2.1269 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.09983.09983.2 0.0268 16-Aug R.SLVNLGGSK.S sp|P04264|K2C1_HUMAN 1 873.492 111.28 27960 9983 2 873.492401 437.7533 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.47 2487.9 - 304067 - - - 0.4797 - 1.398 0.409 - 221.5 1 2 0 0.0004 9 0 0 0 4.60E+07 4.14E+05 - - - 3.031 1 230117_WJC_METTL3_WT_vs_EV_F04.10014.10014.2 3.43E-07 22-Nov R.AQVQEFC[160.03]DYGTK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1444.6293 8.83 27967 10014 2 1444.631143 723.3219 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2492.9 - 253061 - - - 1.2896 - 2.31 0.637 - 393.7 1 2 0 0.0019 12 0 0 0 2.37E+07 2.68E+06 - - - 5.9482 0.9916 230117_WJC_METTL3_WT_vs_EV_F04.10021.10021.2 0.204 22-Mar R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 8.83 27969 10021 2 1452.641084 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2494 - 41105.8 - - - -1.6494 - 1.041 0.345 - 24.3 1 2 0 -0.0024 12 0 0 0 2.37E+07 2.68E+06 - - - 1.6941 0.8721 230117_WJC_METTL3_WT_vs_EV_F04.10025.10025.2 0.0765 12-Aug G.IIEPSLR.Q "sp|P62987|RL40_HUMAN,tr|M0R1A4|M0R1A4_HUMAN,tr|M0QZ32|M0QZ32_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|M0R1M6|M0R1M6_HUMAN" 5 826.4913 1.24 27970 10025 2 826.492525 414.2529 Ubiquitin-60S ribosomal protein L40 OS=Homo sapiens OX=9606 GN=UBA52 PE=1 SV=2 6 2494.5 - 2.45E+06 - - - 1.539 - 1.747 0.134 - 226.6 1 1 0 0.0013 7 0 0 0 8.09E+08 6.51E+08 - - - 1.7981 0.9967 230117_WJC_METTL3_WT_vs_EV_F04.10045.10045.2 0.0606 16-Jul R.GPLVNASLR[166.11].A "sp|O14744|ANM5_HUMAN,tr|H0YJ77|H0YJ77_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 3 935.5428 0.51 27972 10045 2 935.543604 468.7787 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 9.75 2498 - 63600.1 - - - 0.8754 - 1.294 0.209 - 120.3 1 2 0 0.0008 9 0 0 0 2.77E+06 5.45E+06 - - - 1.3301 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.10052.10052.2 0.207 14-Jul R.VMGLVPAK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 821.4924 1.69 27973 10052 2 821.493569 411.7535 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.72 2499.2 - 447849 - - - 1.367 - 1.137 0.282 - 139.5 1 2 0 0.0011 8 0 0 0 3.38E+07 2.00E+07 - - - 1.5107 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.10056.10056.2 0.16 12-Jun R.LMDVMAK.E sp|Q12874|SF3A3_HUMAN 1 806.403 3.1 27974 10056 2 806.404469 404.2088 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2499.7 - 483143 - - - 1.782 - 1.285 0.249 - 106.6 1 2 0 0.0014 7 0 0 0 9.19E+07 2.96E+07 - - - 1.6742 0.9845 230117_WJC_METTL3_WT_vs_EV_F04.10132.10132.2 3.9 14-Jun R.IIAEALTR[166.11].V "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 5 895.5366 0.97 27988 10132 2 895.537791 448.7756 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 2512 - 841225 - - - 1.2886 - 1.119 0.107 - 90.8 1 2 0 0.0012 8 0 0 0 4.94E+07 5.07E+07 - - - 0.17 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.10164.10164.2 1.51 16-Sep K.VELQELNDR.F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1114.5619 4.32 27993 10164 2 1114.565065 558.2882 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.14 2517.1 - 273352 - - - 2.8827 - 1.873 0.265 - 417.1 1 2 0 0.0032 9 0 0 0 2.44E+07 5.63E+06 - - - 2.8128 0.9609 230117_WJC_METTL3_WT_vs_EV_F04.10187.10187.2 2.22 12-May R.VLYSLAK[136.11].K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 800.4887 1.35 27996 10187 2 800.48836 401.2516 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.56 2520.9 - 484619 - - - -0.476 - 1.237 0.108 - 80.1 15 2 0 -0.0004 7 0 0 0 5.93E+07 4.38E+07 - - - -0.0129 0.9935 230117_WJC_METTL3_WT_vs_EV_F04.10191.10191.2 0.0482 12-Jul R.VLYSLAK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 792.4745 1.4 27997 10191 2 792.474173 397.2445 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.56 2521.5 - 653126 - - - -0.4644 - 1.527 0.122 - 177 1 2 0 -0.0004 7 0 0 0 6.15E+07 4.39E+07 - - - 1.2832 0.9583 230117_WJC_METTL3_WT_vs_EV_F04.10237.10237.2 6.83 12-Jun R.LYTVVPR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 846.4963 1.58 28006 10237 2 846.496695 424.2554 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 2528.5 - 1.16E+06 - - - 0.4206 - 1.066 0.072 - 121.6 2 2 0 0.0004 7 0 0 0 1.48E+08 9.36E+07 - - - -0.3593 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.10272.10272.2 0.0038 12-Jul R.LYTVVPR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 856.5046 1.58 28011 10272 2 856.505962 429.2596 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 2534.1 - 1.53E+06 - - - 1.5797 - 1.373 0.299 - 203 1 2 0 0.0014 7 0 0 0 1.48E+08 9.36E+07 - - - 2.2534 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.10278.10278.2 0.00433 14-Oct K.IPAMTIAK[136.11].N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.503 2.19 28014 10278 2 851.503848 426.7588 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2534.9 - 2.02E+06 - - - 0.9841 - 1.758 0.312 - 268.1 1 2 0 0.0008 8 0 0 0 1.82E+09 8.31E+08 - - - 3.0467 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.10280.10280.2 0.158 14-Aug K.IPAMTIAK.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.4888 2.19 28015 10280 2 843.489566 422.7517 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2535.2 - 3.68E+06 - - - 0.8963 - 1.376 0.284 - 173.5 1 2 0 0.0008 8 0 0 0 1.82E+09 8.31E+08 - - - 2.101 0.998 230117_WJC_METTL3_WT_vs_EV_F04.10296.10296.2 0.00421 16-Jul R.VLPVYGGPK.G "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 928.5382 1.62 28022 10296 2 928.537998 465.2764 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 8.56 2537.4 - 105623 - - - -0.2208 - 1.384 0.297 - 111 1 2 0 -0.0002 9 0 0 0 1.91E+07 1.18E+07 - - - 2.1748 0.977 230117_WJC_METTL3_WT_vs_EV_F04.10351.10351.2 2.79 12-May R.LAVYIDK.V "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 820.4695 1.09 28033 10351 2 820.468992 411.242 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.83 2545.7 - 421936 - - - -0.5643 - 1.198 0.123 - 66.7 2 2 0 -0.0005 7 0 0 0 1.59E+07 1.46E+07 - - - 0.3873 0.9775 230117_WJC_METTL3_WT_vs_EV_F04.10353.10353.2 1.28 14-Aug R.LLTGPVVR.G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 853.5385 2.23 28034 10353 2 853.535872 427.7765 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2545.9 - 6.44E+06 - - - -3.1235 - 1.521 0.18 - 173.4 1 2 0 -0.0027 8 0 0 0 3.02E+08 1.36E+08 - - - 1.6344 0.9666 230117_WJC_METTL3_WT_vs_EV_F04.10354.10354.2 4.48 14-Aug R.LLTGPVVR[166.11].G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 863.5468 2.23 28035 10354 2 863.544014 432.7807 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2545.9 - 4.18E+06 - - - -3.2355 - 1.389 0.179 - 172.9 1 2 0 -0.0028 8 0 0 0 3.02E+08 1.36E+08 - - - 1.3532 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.10410.10410.2 0.237 16-Aug K.LSDGVAVLK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 900.528 2.88 28038 10410 2 900.52897 451.2713 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2555.3 - 3.70E+06 - - - 1.0405 - 1.502 0.246 - 140.8 1 2 0 0.0009 9 0 0 0 2.03E+08 7.06E+07 - - - 2.0345 0.8777 230117_WJC_METTL3_WT_vs_EV_F04.10459.10459.2 2.46 12-Jun K.GDVQTIR.W sp|Q702N8|XIRP1_HUMAN 1 787.4188 999 28040 10459 2 787.416777 394.7167 Xin actin-binding repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=XIRP1 PE=1 SV=1 5.84 2563.5 - 8.63E+06 - - - -2.5907 - 1.234 0.048 - 228.2 1 2 0 -0.002 7 0 0 0 3.59E+08 0.00E+00 - - - 0.0611 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.10463.10463.2 0.000116 12-Jul R.LVDMMER.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 892.4147 1.24 28042 10463 2 892.412824 447.2146 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 2564 - 2.61E+06 - - - -2.0562 - 1.487 0.524 - 172.2 1 2 0 -0.0018 7 0 0 0 1.43E+08 1.15E+08 - - - 4.1678 0.9656 230117_WJC_METTL3_WT_vs_EV_F04.10490.10490.2 0.000993 14-Sep K.PSPLLVGR.E "sp|Q13283|G3BP1_HUMAN,sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2R0|A0A7I2V2R0_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RGJ4|D6RGJ4_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|D6R9A4|D6R9A4_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|E5RI46|E5RI46_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 25 837.5072 1.04 28044 10490 2 837.507088 419.7609 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 10.18 2568.5 - 1.39E+06 - - - -0.1791 - 1.933 0.447 - 315 1 1 0 -0.0001 8 0 0 0 1.20E+08 1.15E+08 - - - 4.3302 0.9943 230117_WJC_METTL3_WT_vs_EV_F04.10512.10512.2 0.527 12-Jun K.FIGELGK.L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 762.4276 2.25 28047 10512 2 762.427226 382.2211 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2571.9 - 1.30E+06 - - - -0.4774 - 1.439 0.163 - 150.1 1 2 0 -0.0004 7 0 0 0 2.40E+08 1.07E+08 - - - 1.398 0.9309 230117_WJC_METTL3_WT_vs_EV_F04.10517.10517.2 1.32 12-Jul K.LVVALSR[166.11].T "sp|Q9BPX3|CND3_HUMAN,tr|D6RA93|D6RA93_HUMAN" 2 766.494 0.01 28049 10517 2 766.490831 384.2543 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 9.75 2572.5 - 1.15E+06 - - - -4.1918 - 1.407 0.167 - 180.4 2 2 0 -0.0032 7 0 0 0 1.08E+06 7.46E+07 - - - 1.2209 0.9878 230117_WJC_METTL3_WT_vs_EV_F04.10527.10527.2 0.0647 14-Aug R.VVLLAEGR.L sp|O43865|SAHH2_HUMAN 1 855.5178 3.01 28050 10527 2 855.514999 428.7662 S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1 PE=1 SV=2 5.97 2574.1 - 1.21E+06 - - - -3.2764 - 1.253 0.35 - 208.4 1 2 0 -0.0028 8 0 0 0 4.37E+07 1.46E+07 - - - 2.3054 0.9729 230117_WJC_METTL3_WT_vs_EV_F04.10533.10533.2 0.0344 12-Jul K.FIGELGK[136.11].L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 770.4418 2.15 28051 10533 2 770.439519 386.2282 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2575 - 1.09E+06 - - - -2.9477 - 1.494 0.145 - 184.9 1 2 0 -0.0023 7 0 0 0 2.29E+08 1.06E+08 - - - 1.3833 0.9936 230117_WJC_METTL3_WT_vs_EV_F04.10566.10566.2 0.00561 14-Aug R.LGPLQVAR.V sp|P38117|ETFB_HUMAN 1 852.5181 3.03 28054 10566 2 852.515639 427.2663 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 9.75 2580.4 - 3.32E+06 - - - -2.9301 - 1.683 0.296 - 259.3 1 2 0 -0.0025 8 0 0 0 2.37E+08 7.83E+07 - - - 2.7965 0.9816 230117_WJC_METTL3_WT_vs_EV_F04.10596.10596.2 1.03 12-May R.LVNIVPK[136.11].K "sp|Q8NEY8|PPHLN_HUMAN,tr|F8VRK2|F8VRK2_HUMAN,tr|F8VWU8|F8VWU8_HUMAN,tr|F8VXV7|F8VXV7_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8VPY7|F8VPY7_HUMAN" 6 789.5204 0.86 28060 10596 2 789.519077 395.7675 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 8.75 2584.8 - 2.45E+06 - - - -1.644 - 1.378 0.163 - 64.9 3 2 0 -0.0013 7 0 0 0 1.82E+08 2.12E+08 - - - 1.0473 0.9799 230117_WJC_METTL3_WT_vs_EV_F04.10603.10603.2 0.909 12-Jun K.AIFAGYK.R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 768.417 0.79 28062 10603 2 768.416663 385.2158 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2585.8 - 1.16E+06 - - - -0.4724 - 1.153 0.147 - 126.2 2 2 0 -0.0004 7 0 0 0 2.36E+08 2.97E+08 - - - 0.4433 0.8931 230117_WJC_METTL3_WT_vs_EV_F04.10609.10609.2 0.375 14-Aug K.SVLAGPLR[166.11].T sp|Q9UBZ4|APEX2_HUMAN 1 821.4999 1.06 28064 10609 2 821.495429 411.7572 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 9.47 2586.7 - 1.07E+06 - - - -5.3914 - 1.355 0.201 - 205.7 1 2 0 -0.0044 8 0 0 0 2.86E+07 2.69E+07 - - - 1.4404 0.9925 230117_WJC_METTL3_WT_vs_EV_F04.10611.10611.2 0.269 12-Jun K.AIFAGYK[136.11].R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 776.4312 0.78 28065 10611 2 776.430876 389.2229 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2586.9 - 2.55E+06 - - - -0.4508 - 1.218 0.203 - 155.4 1 2 0 -0.0003 7 0 0 0 2.36E+08 3.04E+08 - - - 1.1651 0.9798 230117_WJC_METTL3_WT_vs_EV_F04.10627.10627.2 0.629 12-May R.FLAPYGR.Q "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 822.4388 0.28 28070 10627 2 822.442176 412.2267 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 8.75 2589.2 - 759529 - - - 4.0757 - 1.13 0.199 - 99.3 1 2 0 0.0034 7 0 0 0 5.83E+07 2.11E+08 - - - 0.897 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.10653.10653.2 0.000799 16-Aug R.QEYEQLIAK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1120.5764 0.56 28073 10653 2 1120.580218 561.2955 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.53 2593.4 - 241801 - - - 3.3715 - 1.743 0.415 - 232 1 2 0 0.0038 9 0 0 0 1.53E+07 2.72E+07 - - - 3.7124 0.9939 230117_WJC_METTL3_WT_vs_EV_F04.10661.10661.2 0.0854 12-Aug R.FLAPYGR[166.11].Q "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 832.4471 0.28 28074 10661 2 832.446716 417.2308 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 8.75 2594.7 - 980582 - - - -0.4541 - 1.292 0.2 - 233.4 1 2 0 -0.0004 7 0 0 0 5.78E+07 2.07E+08 - - - 1.3298 0.9936 230117_WJC_METTL3_WT_vs_EV_F04.10673.10673.2 0.295 12-Jul R.VLISSLK.D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 758.4902 0.97 28077 10673 2 758.49068 380.2524 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2596.4 - 351340 - - - 0.6447 - 1.433 0.094 - 147.9 1 2 0 0.0005 7 0 0 0 9.15E+07 9.45E+07 - - - 0.8751 0.9949 230117_WJC_METTL3_WT_vs_EV_F04.10675.10675.2 0.202 12-Jul R.LPPDVLR.W sp|P78527|PRKDC_HUMAN 1 808.4807 19.22 28078 10675 2 808.481291 405.2476 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2596.6 - 897361 - - - 0.7446 - 1.329 0.145 - 177.3 1 2 0 0.0006 7 0 0 0 1.45E+09 7.55E+07 - - - 1.013 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.10680.10680.2 0.00198 14-Jul K.YVPLADVK[136.11].S "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 911.5208 0.82 28079 10680 2 911.521173 456.7677 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.83 2597.4 - 1.13E+06 - - - 0.4432 - 1.287 0.324 - 193.1 1 2 0 0.0004 8 0 0 0 5.49E+07 6.70E+07 - - - 2.1949 0.9798 230117_WJC_METTL3_WT_vs_EV_F04.10689.10689.2 1.58 12-Jun K.SVLTPLR[166.11].G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 794.489 1.2 28081 10689 2 794.48831 398.2518 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2598.7 - 649376 - - - -0.8169 - 1.207 0.129 - 121.7 1 2 0 -0.0006 7 0 0 0 5.25E+07 4.36E+07 - - - 0.5897 0.9945 230117_WJC_METTL3_WT_vs_EV_F04.10710.10710.2 0.183 12-Jun K.SVLTPLR.G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 784.4807 1.18 28090 10710 2 784.480843 393.2476 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2601.6 - 944690 - - - 0.1963 - 1.191 0.207 - 141.8 1 2 0 0.0002 7 0 0 0 5.37E+07 4.55E+07 - - - 1.1237 0.9925 230117_WJC_METTL3_WT_vs_EV_F04.10715.10715.2 0.173 12-May R.LLDVYEK.E "sp|Q96EF6|FBX17_HUMAN,tr|M0R2C6|M0R2C6_HUMAN,tr|M0QZ95|M0QZ95_HUMAN" 3 878.4749 1.21 28093 10715 2 878.473824 440.2447 F-box only protein 17 OS=Homo sapiens OX=9606 GN=FBXO17 PE=1 SV=1 4.37 2602.3 - 217773 - - - -1.2636 - 1.205 0.263 - 56 1 2 0 -0.0011 7 0 0 0 9.63E+06 7.98E+06 - - - 1.574 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.10718.10718.2 1.58 12-Jun R.VLISSLK[136.11].D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 766.5044 1.19 28094 10718 2 766.505037 384.2595 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2602.7 - 1.59E+06 - - - 0.8428 - 1.36 0.143 - 156.6 1 2 0 0.0006 7 0 0 0 8.94E+07 7.51E+07 - - - 1.0713 0.9929 230117_WJC_METTL3_WT_vs_EV_F04.10739.10739.2 1.84 12-Jul R.IVEGILK.R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 770.4902 2.08 28100 10739 2 770.490672 386.2524 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 2605.8 - 1.32E+06 - - - 0.6243 - 1.459 0.094 - 125.7 2 2 0 0.0005 7 0 0 0 6.70E+08 3.23E+08 - - - 0.7976 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.10740.10740.2 3.58 12-Jul R.IVEGILK[136.11].R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 778.5044 2.08 28101 10740 2 778.504668 390.2595 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 2605.9 - 864977 - - - 0.3558 - 1.541 0.16 - 108.2 1 2 0 0.0003 7 0 0 0 6.70E+08 3.22E+08 - - - 1.5929 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.10753.10753.2 0.0115 12-Aug K.MGITPLR.N "sp|Q12789|TF3C1_HUMAN,sp|O43325|LYRM1_HUMAN,tr|H3BNA8|H3BNA8_HUMAN" 3 786.4422 1.05 28104 10753 2 786.442611 394.2284 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 9.5 2607.9 - 431388 - - - 0.529 - 1.745 0.277 - 236.9 1 2 0 0.0004 7 0 0 0 4.91E+07 4.65E+07 - - - 2.8509 1 230117_WJC_METTL3_WT_vs_EV_F04.10765.10765.2 2.90E-07 26-Nov R.SLYASSPGGVYATR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1427.7045 1.79 28108 10765 2 1427.707888 714.8595 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2609.7 - 72917.6 - - - 2.3772 - 2.199 0.584 - 315.3 1 2 0 0.0034 14 0 0 0 7.20E+06 4.02E+06 - - - 5.3308 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.10769.10769.2 0.0504 18-Jul R.IITEGFEAAK.E sp|P40227|TCPZ_HUMAN 1 1077.5706 10.38 28110 10769 2 1077.571889 539.7926 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 2610.1 - 319443 - - - 1.1721 - 1.507 0.266 - 98.8 1 2 0 0.0013 10 0 0 0 3.45E+07 3.33E+06 - - - 2.1501 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.10789.10789.2 0.118 12-Aug K.LTGMAFR.V "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 794.4109 2.72 28118 10789 2 794.412127 398.2127 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 9.75 2613 - 1.11E+06 - - - 1.5521 - 1.839 0.298 - 201.1 1 2 0 0.0012 7 0 0 0 1.17E+10 4.30E+09 - - - 3.172 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.10795.10795.2 0.052 14-Jun R.VIQALAMK.G "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 872.5154 1.21 28120 10795 2 872.516326 437.265 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.72 2613.8 - 376302 - - - 1.1071 - 1.378 0.22 - 88.8 1 2 0 0.001 8 0 0 0 2.04E+07 1.69E+07 - - - 1.6326 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.10798.10798.2 0.000208 26-Jun R.SLYASSPGGVYATR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1437.7128 1.79 28121 10798 2 1437.717512 719.8637 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2614.2 - 113400 - - - 3.3025 - 1.456 0.426 - 68.7 1 2 0 0.0047 14 0 0 0 7.20E+06 4.02E+06 - - - 3.1287 0.9538 230117_WJC_METTL3_WT_vs_EV_F04.10812.10812.2 5.11 14-Jun R.QLLAPVVK.E "sp|Q13576|IQGA2_HUMAN,sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|F5H7S7|F5H7S7_HUMAN,tr|E7EWC2|E7EWC2_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 6 866.5589 1.23 28128 10812 2 866.559334 434.2867 Ras GTPase-activating-like protein IQGAP2 OS=Homo sapiens OX=9606 GN=IQGAP2 PE=1 SV=4 8.75 2616 - 328418 - - - 0.4558 - 1.081 0.039 - 79 1 2 0 0.0004 8 0 0 0 1.13E+07 9.21E+06 - - - -0.4362 0.9969 230117_WJC_METTL3_WT_vs_EV_F04.10823.10823.2 1.8 12-Aug R.MGLVMDR[166.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 830.4018 2.12 28132 10823 2 830.402317 416.2082 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2617.4 - 306702 - - - 0.6226 - 1.548 0.156 - 193.9 2 2 0 0.0005 7 0 0 0 1.11E+09 5.26E+08 - - - 1.4431 0.8807 230117_WJC_METTL3_WT_vs_EV_F04.10825.10825.2 0.185 16-Sep R.PGPLLVSAR.R sp|Q9NUL7|DDX28_HUMAN 1 908.5444 1.21 28133 10825 2 908.544077 455.2795 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 10.18 2617.6 - 321802 - - - -0.3016 - 1.879 0.21 - 260.4 1 1 0 -0.0003 9 0 0 0 6.64E+07 5.49E+07 - - - 2.4167 0.993 230117_WJC_METTL3_WT_vs_EV_F04.10830.10830.2 2.46 12-Jul R.LIITQVR.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 841.5385 0.99 28135 10830 2 841.538287 421.7765 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 9.75 2618.3 - 8.90E+06 - - - -0.2983 - 1.406 0.139 - 181.2 1 2 0 -0.0003 7 0 0 0 4.05E+08 4.08E+08 - - - 1.1473 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.10835.10835.2 5.66E-05 16-Sep K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 0.79 28137 10835 2 993.582934 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2618.9 - 348406 - - - -1.7271 - 1.891 0.467 - 231.1 1 2 0 -0.0017 9 0 0 0 6.81E+07 8.63E+07 - - - 4.3329 0.997 230117_WJC_METTL3_WT_vs_EV_F04.10837.10837.2 0.000475 20-Sep K.FGDPVVQSDMK.H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1221.57 0.44 28138 10837 2 1221.567983 611.7923 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.21 2619.1 - 372447 - - - -1.6299 - 1.423 0.368 - 221.7 1 2 0 -0.002 11 0 0 0 1.17E+07 2.68E+07 - - - 2.7127 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.10848.10848.2 0.000982 22-Sep R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 1082.76 28142 10848 2 1474.778286 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2620.6 - 212971 - - - 0.1987 - 1.951 0.42 - 128.9 1 2 0 0.0003 12 0 0 0 3.37E+07 3.11E+04 - - - 3.9015 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.10850.10850.2 0.00392 12-Jul R.MGLVMDR.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 820.3935 2.12 28143 10850 2 820.392035 411.204 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2620.8 - 3.98E+06 - - - -1.8223 - 1.648 0.292 - 204.3 1 2 0 -0.0015 7 0 0 0 1.11E+09 5.26E+08 - - - 2.7801 0.9723 230117_WJC_METTL3_WT_vs_EV_F04.10860.10860.2 0.00122 16-Dec R.PGPLLVSAR[166.11].R sp|Q9NUL7|DDX28_HUMAN 1 918.5526 41.68 28144 10860 2 918.553279 460.2836 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 10.18 2622.5 - 981904 - - - 0.7163 - 2.005 0.388 - 444.8 1 1 0 0.0007 9 0 0 0 2.89E+09 6.94E+07 - - - 3.9191 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.10867.10867.2 0.00105 16-Sep K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 0.79 28145 10867 2 983.575395 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2623.5 - 741638 - - - -1.0014 - 1.908 0.429 - 355 1 2 0 -0.001 9 0 0 0 6.80E+07 8.63E+07 - - - 4.0784 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.10880.10880.2 0.00204 20-Sep K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 3622.86 28147 10880 2 1106.547043 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2625.6 - 429932 - - - 0.5793 - 2.097 0.448 - 204.4 1 2 0 0.0006 11 0 0 0 1.88E+09 5.19E+05 - - - 4.353 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.10899.10899.2 0.00178 14-Jun R.NGYGFINR.N "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 4 939.4563 0.3 28152 10899 2 939.456394 470.7354 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 8.75 2628.4 - 197241 - - - 0.1373 - 1.461 0.314 - 106.6 1 2 0 0.0001 8 0 0 0 7.00E+06 2.31E+07 - - - 2.5036 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.10904.10904.2 0.012 16-Jul K.EIAEAYLGK.T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 992.5179 9.92 28154 10904 2 992.518779 497.2662 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 2629.2 - 1.59E+06 - - - 0.9239 - 1.392 0.177 - 171.1 1 2 0 0.0009 9 0 0 0 5.54E+07 5.59E+06 - - - 1.3049 0.999 230117_WJC_METTL3_WT_vs_EV_F04.10919.10919.2 0.037 14-Jun R.VITALVER.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 899.544 0.36 28159 10919 2 899.544847 450.7793 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2631.2 - 1.45E+06 - - - 0.9227 - 1.569 0.268 - 89.2 1 2 0 0.0008 8 0 0 0 3.26E+09 9.05E+09 - - - 2.3787 0.9842 230117_WJC_METTL3_WT_vs_EV_F04.10940.10940.2 0.84 12-May R.LPPDVLR.W sp|P78527|PRKDC_HUMAN 1 808.4807 2.31 28168 10940 2 808.481228 405.2476 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2634.3 - 263891 - - - 0.6667 - 1.199 0.101 - 77.7 2 2 0 0.0005 7 0 0 0 7.01E+07 3.04E+07 - - - 0.2274 0.9921 230117_WJC_METTL3_WT_vs_EV_F04.10942.10942.2 0.299 12-Jul R.LILPEAK[136.11].V "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN,tr|A8MSZ8|A8MSZ8_HUMAN" 3 790.5044 1.4 28169 10942 2 790.504405 396.2595 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 6 2634.5 - 1.48E+06 - - - 0.0177 - 1.376 0.117 - 121.2 1 2 0 0 7 0 0 0 1.03E+08 7.37E+07 - - - 0.9165 0.9793 230117_WJC_METTL3_WT_vs_EV_F04.10951.10951.2 1.89 14-Jul R.LLVVTDPR[166.11].A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 921.5523 2.89 28172 10951 2 921.55066 461.7834 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.84 2635.7 - 821638 - - - -1.7655 - 1.4 0.13 - 118.8 1 2 0 -0.0016 8 0 0 0 1.60E+09 5.54E+08 - - - 1.0155 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.10954.10954.2 0.455 12-Aug R.LNELLVK.A "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L253|I3L253_HUMAN" 3 827.5117 2.14 28174 10954 2 827.51198 414.7631 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2636.1 - 1.08E+06 - - - 0.394 - 1.726 0.218 - 199.4 1 2 0 0.0003 7 0 0 0 5.55E+08 2.59E+08 - - - 2.3805 0.9889 230117_WJC_METTL3_WT_vs_EV_F04.10957.10957.2 3.29 12-Aug R.LNELLVK[136.11].A "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L253|I3L253_HUMAN" 3 835.5259 2.11 28175 10957 2 835.526479 418.7702 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2636.5 - 936131 - - - 0.748 - 1.556 0.002 - 132.9 1 2 0 0.0006 7 0 0 0 5.55E+08 2.63E+08 - - - 0.4565 0.997 230117_WJC_METTL3_WT_vs_EV_F04.10962.10962.2 0.0877 12-Jul K.AC[160.03]TILLR.G "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 845.4793 13.93 28176 10962 2 845.480905 423.7469 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 8.29 2637.2 - 5.28E+06 - - - 1.8877 - 1.347 0.196 - 340.5 1 2 0 0.0016 7 0 0 0 4.47E+08 3.21E+07 - - - 1.432 0.883 230117_WJC_METTL3_WT_vs_EV_F04.10996.10996.2 5.18 14-Jun K.ILPVGGIK[136.11].E "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN,tr|K7ERR6|K7ERR6_HUMAN" 4 803.536 1.33 28184 10996 2 803.535793 402.7753 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 8.75 2642.1 - 557908 - - - -0.2887 - 0.915 0.073 - 83 2 2 0 -0.0002 8 0 0 0 4.86E+07 3.66E+07 - - - -0.8223 0.9957 230117_WJC_METTL3_WT_vs_EV_F04.11014.11014.2 0.293 14-Jul K.IEISELNR.V "sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 2 972.524 124.59 28189 11014 2 972.524945 487.2693 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2644.7 - 369449 - - - 0.9614 - 1.456 0.126 - 160 1 2 0 0.0009 8 0 0 0 6.72E+07 5.40E+05 - - - 1.1044 0.9816 230117_WJC_METTL3_WT_vs_EV_F04.11019.11019.2 0.251 12-Jun R.LISVLNK.S "sp|Q9Y450|HBS1L_HUMAN,tr|H0YDX7|H0YDX7_HUMAN,tr|B7Z524|B7Z524_HUMAN,tr|J3QT46|J3QT46_HUMAN" 4 785.5011 0.49 28192 11019 2 785.503325 393.7578 HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1 8.75 2645.4 - 312366 - - - 2.8453 - 1.402 0.068 - 90.2 3 2 0 0.0022 7 0 0 0 3.43E+07 6.98E+07 - - - 0.4001 0.9958 230117_WJC_METTL3_WT_vs_EV_F04.11021.11021.2 0.308 14-Jul R.AIVPLEAR.M "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 867.5178 1.92 28193 11021 2 867.520757 434.7662 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 6.05 2645.7 - 738500 - - - 3.4063 - 1.535 0.22 - 203.9 2 2 0 0.003 8 0 0 0 9.63E+07 5.03E+07 - - - 1.8229 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.11023.11023.2 1.4 14-Jul R.LLVVTDPR.A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 911.544 2.89 28194 11023 2 911.546289 456.7793 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.84 2645.9 - 1.85E+07 - - - 2.4925 - 1.544 0.238 - 177 1 2 0 0.0023 8 0 0 0 1.60E+09 5.54E+08 - - - 2.1082 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.11025.11025.2 0.000445 22-Sep K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 2.31 28196 11025 2 1222.668014 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2646.2 - 183779 - - - 2.5739 - 1.925 0.426 - 253.9 1 2 0 0.0031 12 0 0 0 9.36E+07 4.06E+07 - - - 3.9097 0.9427 230117_WJC_METTL3_WT_vs_EV_F04.11029.11029.2 0.0187 14-Jul Q.VLVLAPTR[166.11].E "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 877.5625 0.91 28198 11029 2 877.563645 439.7885 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.72 2646.7 - 593344 - - - 1.3526 - 1.489 0.33 - 210.4 1 1 0 0.0012 8 0 0 0 1.18E+08 1.30E+08 - - - 2.6787 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.11030.11030.2 1.56E-05 22-Nov K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 2.31 28199 11030 2 1214.652753 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2646.8 - 498720 - - - 1.7174 - 2.281 0.456 - 436.9 1 2 0 0.0021 12 0 0 0 9.36E+07 4.06E+07 - - - 4.5781 0.9818 230117_WJC_METTL3_WT_vs_EV_F04.11037.11037.2 0.298 14-Aug R.ILMAINGK.V sp|O00264|PGRC1_HUMAN 1 858.4997 0.82 28202 11037 2 858.503082 430.2571 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 8.75 2647.7 - 611740 - - - 3.9289 - 1.339 0.133 - 142.6 1 2 0 0.0034 8 0 0 0 7.93E+07 9.65E+07 - - - 0.9027 0.9284 230117_WJC_METTL3_WT_vs_EV_F04.11040.11040.2 4.12 12-Jun R.LIPTELR[166.11].R "sp|Q96G21|IMP4_HUMAN,tr|F8WCN0|F8WCN0_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN" 4 850.5152 1.12 28204 11040 2 850.51842 426.2649 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2648.1 - 138164 - - - 3.8177 - 1.132 0.111 - 121.6 7 2 0 0.0032 7 0 0 0 1.61E+08 1.45E+08 - - - -0.1248 0.921 230117_WJC_METTL3_WT_vs_EV_F04.11052.11052.2 0.0209 14-Jul Q.VLVLAPTR.E "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 867.5542 0.91 28208 11052 2 867.555373 434.7844 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.72 2649.7 - 1.57E+06 - - - 1.3659 - 1.553 0.262 - 156.5 1 1 0 0.0012 8 0 0 0 1.18E+08 1.30E+08 - - - 2.3033 0.9463 230117_WJC_METTL3_WT_vs_EV_F04.11060.11060.4 0.00352 15/114 K.RGLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2236.1236 3.44 28211 11060 4 2236.136784 560.0382 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2650.9 - 156693 - - - 5.8758 - 1.693 0.274 - 75.9 1 2 0 0.0131 20 0 0 0 7.35E+06 2.14E+06 - - - 1.7833 0.9969 230117_WJC_METTL3_WT_vs_EV_F04.11078.11078.2 0.114 12-Jun R.LIPTELR.R "sp|Q96G21|IMP4_HUMAN,tr|F8WCN0|F8WCN0_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN" 4 840.5069 1.01 28216 11078 2 840.507489 421.2607 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2653.5 - 1.78E+06 - - - 0.6972 - 1.233 0.234 - 157.8 1 2 0 0.0006 7 0 0 0 1.61E+08 1.59E+08 - - - 1.4328 0.9362 230117_WJC_METTL3_WT_vs_EV_F04.11085.11085.2 0.988 18-May K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 1.63 28218 11085 2 1008.595453 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2654.6 - 165202 - - - -1.3167 - 1.057 0.156 - 55.5 6 2 0 -0.0013 10 0 0 0 1.32E+07 8.09E+06 - - - -0.0001 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.11099.11099.2 0.0259 14-Aug K.GIYALAAR.D "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 833.4759 0.8 28221 11099 2 833.476534 417.7452 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 8.75 2656.7 - 841319 - - - 0.7151 - 1.677 0.277 - 223.6 1 2 0 0.0006 8 0 0 0 6.55E+07 8.16E+07 - - - 2.646 0.999 230117_WJC_METTL3_WT_vs_EV_F04.11114.11114.2 0.0381 12-Jul K.SVLIMGR[166.11].G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 784.4505 1.66 28228 11114 2 784.452583 393.2325 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.47 2658.7 - 366364 - - - 2.7 - 1.61 0.319 - 197.9 1 2 0 0.0021 7 0 0 0 8.83E+07 5.31E+07 - - - 2.9054 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.11122.11122.2 0.00934 12-Aug K.DDAMLLK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 804.4051 1.31 28230 11122 2 804.406533 403.2098 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.21 2659.9 - 1.00E+06 - - - 1.7317 - 1.749 0.324 - 332.5 1 2 0 0.0014 7 0 0 0 3.84E+07 2.92E+07 - - - 3.205 0.9074 230117_WJC_METTL3_WT_vs_EV_F04.11124.11124.2 0.91 12-Jul K.FIEIAAR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 818.465 0.96 28231 11124 2 818.463846 410.2398 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2660.1 - 4.05E+06 - - - -1.4564 - 1.232 0.013 - 145.4 1 2 0 -0.0012 7 0 0 0 3.21E+10 3.34E+10 - - - -0.2023 0.9879 230117_WJC_METTL3_WT_vs_EV_F04.11128.11128.2 0.0191 20-Jul K.IGGIGTVPVGR.V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1024.6029 5.23 28233 11128 2 1024.599645 513.3087 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2660.6 - 302208 - - - -3.2051 - 1.646 0.297 - 109.1 5 2 0 -0.0033 11 0 0 0 8.16E+07 1.56E+07 - - - 2.2695 0.9897 230117_WJC_METTL3_WT_vs_EV_F04.11140.11140.2 0.661 12-Jul K.SVLIMGR.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 774.4422 1.46 28238 11140 2 774.442848 388.2284 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.47 2662.1 - 1.36E+06 - - - 0.8432 - 1.258 0.098 - 205.9 1 2 0 0.0007 7 0 0 0 8.96E+07 6.13E+07 - - - 0.4919 0.9757 230117_WJC_METTL3_WT_vs_EV_F04.11174.11174.2 1.21 12-Jun K.IIPVVVK.M "sp|Q96KG9|SCYL1_HUMAN,tr|E9PPN3|E9PPN3_HUMAN,tr|E9PK59|E9PK59_HUMAN,tr|E9PS17|E9PS17_HUMAN" 4 766.5317 1.92 28249 11174 2 766.530081 384.2731 N-terminal kinase-like protein OS=Homo sapiens OX=9606 GN=SCYL1 PE=1 SV=1 8.75 2666.7 - 870946 - - - -2.0612 - 1.038 0.254 - 98.8 1 2 0 -0.0016 7 0 0 0 5.12E+07 2.67E+07 - - - 1.0347 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.11182.11182.2 0.0102 14-Sep K.IGVTVLSR.L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 843.5178 0.92 28250 11182 2 843.516898 422.7662 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2668 - 2.15E+06 - - - -1.0717 - 1.871 0.301 - 255.9 1 2 0 -0.0009 8 0 0 0 4.48E+08 4.85E+08 - - - 3.1533 0.9729 230117_WJC_METTL3_WT_vs_EV_F04.11188.11188.2 1.24 12-Jul R.VYLGALK[136.11].Y sp|Q6P2Q9|PRP8_HUMAN 1 770.4782 1.04 28253 11188 2 770.477463 386.2464 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.56 2668.7 - 1.29E+06 - - - -0.9254 - 1.225 0.101 - 161.4 1 2 0 -0.0007 7 0 0 0 2.35E+08 2.25E+08 - - - 0.4298 0.9914 230117_WJC_METTL3_WT_vs_EV_F04.11202.11202.2 0.713 14-Jul R.ILMGSTLR[166.11].K "sp|P10644|KAP0_HUMAN,sp|P31321|KAP1_HUMAN,tr|K7EM13|K7EM13_HUMAN,tr|C9JSK5|C9JSK5_HUMAN,tr|K7EKR1|K7EKR1_HUMAN,tr|K7EPB2|K7EPB2_HUMAN,tr|H7BYW5|H7BYW5_HUMAN" 7 899.5138 1.66 28255 11202 2 899.516887 450.7642 cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1A PE=1 SV=1 9.75 2671 - 736693 - - - 3.4396 - 1.345 0.176 - 132.3 1 2 0 0.0031 8 0 0 0 3.37E+07 2.03E+07 - - - 1.2339 0.9841 230117_WJC_METTL3_WT_vs_EV_F04.11214.11214.2 1.92 12-Jul K.LGITQLR[166.11].F "sp|Q9Y285|SYFA_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 3 809.4999 2.82 28258 11214 2 809.501849 405.7572 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 9.75 2672.6 - 1.09E+06 - - - 2.4595 - 1.516 0 - 123.1 1 2 0 0.002 7 0 0 0 1.57E+08 5.59E+07 - - - 0.3587 0.964 230117_WJC_METTL3_WT_vs_EV_F04.11216.11216.2 4.22 12-Sep K.LGITQLR.F "sp|Q9Y285|SYFA_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 3 799.4916 2.52 28259 11216 2 799.48996 400.7531 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 9.75 2672.9 - 2.83E+06 - - - -2.0363 - 1.7 0 - 225.7 1 2 0 -0.0016 7 0 0 0 1.59E+08 6.29E+07 - - - 0.7218 0.9354 230117_WJC_METTL3_WT_vs_EV_F04.11222.11222.2 4 12-May R.VTVPLVR[166.11].R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 792.5097 0.97 28263 11222 2 792.508965 397.2621 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2673.6 - 1.30E+06 - - - -0.9199 - 1.162 0.071 - 86.5 3 2 0 -0.0007 7 0 0 0 4.07E+08 4.21E+08 - - - -0.1722 0.9835 230117_WJC_METTL3_WT_vs_EV_F04.11235.11235.2 0.0939 12-Jun K.LPYSTFR[166.11].T "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 892.4682 1.21 28265 11235 2 892.466317 447.2414 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.75 2675.6 - 1.04E+06 - - - -2.1357 - 1.156 0.255 - 163.4 1 2 0 -0.0019 7 0 0 0 1.93E+08 1.59E+08 - - - 1.3832 0.9962 230117_WJC_METTL3_WT_vs_EV_F04.11237.11237.2 0.0778 12-Jul R.VTVPLVR.R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 782.5014 0.97 28266 11237 2 782.500812 392.258 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2675.8 - 1.99E+06 - - - -0.7821 - 1.457 0.228 - 195.5 1 2 0 -0.0006 7 0 0 0 4.12E+08 4.24E+08 - - - 1.9174 0.9848 230117_WJC_METTL3_WT_vs_EV_F04.11248.11248.2 0.0136 14-May K.VENLFNEK.C "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 991.4975 0.86 28270 11248 2 991.497784 496.756 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2677.3 - 216138 - - - 0.3258 - 1.385 0.043 - 76.8 1 2 0 0.0003 8 0 0 0 3.91E+06 4.56E+06 - - - 0.3408 0.9948 230117_WJC_METTL3_WT_vs_EV_F04.11255.11255.2 2.01 14-Aug K.IGVTVLSR[166.11].L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 853.5261 0.92 28271 11255 2 853.526071 427.7703 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2678.4 - 2.03E+06 - - - -0.0012 - 1.651 0.093 - 187.3 1 2 0 0 8 0 0 0 4.48E+08 4.86E+08 - - - 1.24 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.11287.11287.2 0.119 14-Aug K.LGDLGLGR[166.11].F "sp|Q8TDX7|NEK7_HUMAN,sp|Q9HC98|NEK6_HUMAN,tr|Q5TBG7|Q5TBG7_HUMAN,tr|Q5TBG1|Q5TBG1_HUMAN,tr|Q5TBH1|Q5TBH1_HUMAN,tr|Q5TBH2|Q5TBH2_HUMAN,tr|Q5TBH0|Q5TBH0_HUMAN" 7 809.4635 2.38 28281 11287 2 809.463808 405.739 Serine\threonine-protein kinase Nek7 OS=Homo sapiens OX=9606 GN=NEK7 PE=1 SV=1 5.84 2683.1 - 247423 - - - 0.4151 - 1.641 0.152 - 133 1 2 0 0.0003 8 0 0 0 1.75E+07 7.36E+06 - - - 1.6574 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.11306.11306.2 0.000126 18-Sep K.NGQDLGVAFK[136.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1055.5491 1.53 28284 11306 2 1055.549449 528.7818 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2686.2 - 187711 - - - 0.3221 - 1.926 0.404 - 312.3 1 2 0 0.0003 10 0 0 0 4.85E+07 3.16E+07 - - - 3.8544 0.9756 230117_WJC_METTL3_WT_vs_EV_F04.11322.11322.2 1.05 12-Jun R.LIVNIAK[136.11].V sp|Q15058|KIF14_HUMAN 1 777.5204 1.71 28289 11322 2 777.522106 389.7675 Kinesin-like protein KIF14 OS=Homo sapiens OX=9606 GN=KIF14 PE=1 SV=1 8.75 2688.5 - 291037 - - - 2.2263 - 0.975 0.14 - 72.9 1 2 0 0.0017 7 0 0 0 1.47E+07 8.62E+06 - - - -0.0057 0.9461 230117_WJC_METTL3_WT_vs_EV_F04.11324.11324.2 0.0391 14-Sep K.LTGVFAPR.P "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 859.4916 0.99 28290 11324 2 859.492511 430.7531 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2688.7 - 2.30E+07 - - - 1.0739 - 1.819 0.261 - 364.2 1 1 0 0.0009 8 0 0 0 2.20E+09 2.23E+09 - - - 2.7729 0.9969 230117_WJC_METTL3_WT_vs_EV_F04.11325.11325.2 0.923 12-Jul K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 1.52 28291 11325 2 828.474764 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2688.8 - 2.72E+06 - - - 1.7574 - 1.503 0.142 - 206.1 1 2 0 0.0015 7 0 0 0 1.96E+08 1.28E+08 - - - 1.3804 0.999 230117_WJC_METTL3_WT_vs_EV_F04.11328.11328.2 0.0318 12-Jun K.FMTDPIR.L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 878.432 0.92 28292 11328 2 878.43324 440.2233 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2689.2 - 855697 - - - 1.3843 - 1.371 0.323 - 171.7 1 2 0 0.0012 7 0 0 0 9.55E+07 1.04E+08 - - - 2.4261 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.11345.11345.2 0.0401 12-Jun K.FMTDPIR[166.11].L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 888.4403 1.06 28300 11345 2 888.442399 445.2274 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2691.5 - 2.31E+06 - - - 2.3693 - 1.242 0.256 - 133.6 1 2 0 0.0021 7 0 0 0 1.11E+08 1.05E+08 - - - 1.6179 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.11349.11349.2 6.54E-05 14-Aug K.FGPALSVK[136.11].V "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 825.484 3.25 28302 11349 2 825.48572 413.7493 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.75 2692 - 2.31E+06 - - - 2.0957 - 1.751 0.143 - 183.3 1 2 0 0.0017 8 0 0 0 2.06E+09 6.34E+08 - - - 1.7862 0.9864 230117_WJC_METTL3_WT_vs_EV_F04.11363.11363.2 0.0538 12-Jun R.IVYLYTK.K sp|P49207|RL34_HUMAN 1 898.5164 0.74 28309 11363 2 898.52138 450.2655 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 8.5 2693.9 - 645246 - - - 5.5369 - 1.458 0.249 - 114.8 1 2 0 0.005 7 0 0 0 7.70E+08 1.03E+09 - - - 2.0733 0.9811 230117_WJC_METTL3_WT_vs_EV_F04.11366.11366.2 0.116 20-May K.ETTIDGEELVK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1240.6278 1.33 28312 11366 2 1240.632874 621.3212 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4 2694.3 - 83820.4 - - - 4.0794 - 1.233 0.182 - 61.6 1 2 0 0.0051 11 0 0 0 3.12E+06 2.35E+06 - - - 0.9503 0.999 230117_WJC_METTL3_WT_vs_EV_F04.11369.11369.2 0.0741 12-Aug R.IVYLYTK[136.11].K sp|P49207|RL34_HUMAN 1 906.5306 0.74 28313 11369 2 906.533082 454.2726 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 8.5 2694.7 - 2.62E+06 - - - 2.7324 - 1.613 0.322 - 224.8 1 2 0 0.0025 7 0 0 0 7.69E+08 1.03E+09 - - - 2.9334 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.11379.11379.2 0.00135 18-Sep K.NGQDLGVAFK.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1047.5349 1.39 28319 11379 2 1047.537502 524.7747 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2696.1 - 456528 - - - 2.4753 - 1.897 0.403 - 340.5 1 2 0 0.0026 10 0 0 0 4.38E+07 3.16E+07 - - - 3.8039 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.11381.11381.2 1.51 14-Aug R.VLAVTAIR.E sp|P22102|PUR2_HUMAN 1 841.5385 2.48 28320 11381 2 841.540019 421.7765 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2696.4 - 1.25E+06 - - - 1.7599 - 1.857 0.19 - 264.2 1 2 0 0.0015 8 0 0 0 3.43E+08 1.38E+08 - - - 2.3106 0.9935 230117_WJC_METTL3_WT_vs_EV_F04.11382.11382.2 0.186 14-Jun K.ALSVGLVK.G "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 3 785.5011 1.68 28321 11382 2 785.502794 393.7578 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 8.8 2696.5 - 505938 - - - 2.1693 - 1.198 0.179 - 98.1 1 2 0 0.0017 8 0 0 0 1.09E+08 6.45E+07 - - - 0.9074 0.9965 230117_WJC_METTL3_WT_vs_EV_F04.11389.11389.2 2 14-Sep R.VLAVTAIR[166.11].E sp|P22102|PUR2_HUMAN 1 851.5468 2.48 28324 11389 2 851.548653 426.7807 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2697.4 - 1.07E+06 - - - 2.1666 - 1.797 0.079 - 256.3 1 2 0 0.0018 8 0 0 0 3.42E+08 1.38E+08 - - - 1.3916 0.996 230117_WJC_METTL3_WT_vs_EV_F04.11399.11399.2 0.00365 12-Jul K.MMEIMTR[166.11].E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 920.4157 0.86 28329 11399 2 920.416851 461.2151 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2698.8 - 689340 - - - 1.2125 - 1.393 0.144 - 231.2 1 2 0 0.0011 7 0 0 0 1.20E+08 1.40E+08 - - - 1.1545 0.9947 230117_WJC_METTL3_WT_vs_EV_F04.11401.11401.2 0.35 12-Jul K.MMEIMTR.E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 910.4075 0.86 28330 11401 2 910.410456 456.211 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2699.1 - 2.20E+06 - - - 3.2853 - 1.14 0.284 - 104.9 1 2 0 0.003 7 0 0 0 1.20E+08 1.40E+08 - - - 1.5529 0.9934 230117_WJC_METTL3_WT_vs_EV_F04.11415.11415.2 0.834 12-Jul K.YLDEIVK.E sp|P12270|TPR_HUMAN 1 878.4749 1.24 28337 11415 2 878.476085 440.2447 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.37 2700.9 - 550116 - - - 1.3091 - 1.189 0.159 - 147.3 1 2 0 0.0011 7 0 0 0 4.30E+07 3.46E+07 - - - 0.7635 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.11417.11417.2 0.00366 12-Jul K.MMVAGFK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 790.3961 0.88 28339 11417 2 790.396665 396.2053 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2701.1 - 1.67E+06 - - - 0.7123 - 1.468 0.474 - 244.2 1 2 0 0.0006 7 0 0 0 5.39E+09 6.11E+09 - - - 3.7582 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.11418.11418.2 0.0144 16-Aug R.MVGGVLVER[166.11].T sp|Q9UHV9|PFD2_HUMAN 1 968.5353 0.29 28340 11418 2 968.537423 485.2749 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 5.75 2701.2 - 947540 - - - 2.2364 - 1.501 0.262 - 164.1 1 2 0 0.0022 9 0 0 0 6.65E+07 2.31E+08 - - - 2.1504 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.11419.11419.2 2.82 18-Dec K.YEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1178.5932 1044.36 28341 11419 2 1178.593314 590.3039 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2701.3 - 167072 - - - 0.1375 - 2.187 0.288 - 639.5 1 2 0 0.0002 10 0 0 0 2.19E+07 2.09E+04 - - - 3.3524 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.11427.11427.2 0.000233 12-Jul K.MMVAGFK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 782.3819 0.88 28343 11427 2 782.382235 392.1982 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2702.5 - 3.77E+06 - - - 0.4256 - 1.626 0.49 - 206.7 1 2 0 0.0003 7 0 0 0 5.39E+09 6.11E+09 - - - 4.2003 0.9933 230117_WJC_METTL3_WT_vs_EV_F04.11428.11428.2 0.661 14-Aug K.IVGYVLAK[136.11].M "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN" 4 869.5466 1.35 28344 11428 2 869.54682 435.7806 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 8.59 2702.5 - 1.21E+06 - - - 0.2645 - 1.206 0.182 - 143.9 1 2 0 0.0002 8 0 0 0 1.62E+08 1.20E+08 - - - 0.9501 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.11434.11434.2 0.0188 18-May K.C[160.03]PFTGNVSIR[166.11].G "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1159.5683 1.26 28347 11434 2 1159.569865 580.7915 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.25 2703.3 - 103933 - - - 1.3082 - 1.187 0.341 - 78.8 1 2 0 0.0015 10 0 0 0 4.41E+06 3.50E+06 - - - 2.0377 0.9586 230117_WJC_METTL3_WT_vs_EV_F04.11438.11438.2 6.29 12-May R.FAGVDIR.V "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 776.4181 2.65 28348 11438 2 776.417998 389.2163 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 5.84 2703.9 - 920067 - - - -0.1159 - 1.096 0.112 - 64.8 6 2 0 -0.0001 7 0 0 0 4.27E+07 1.61E+07 - - - -0.1889 0.9313 230117_WJC_METTL3_WT_vs_EV_F04.11440.11440.2 8.77 14-Aug R.K[136.11]QNLLASR.E "sp|O00555|CAC1A_HUMAN,tr|A0A1B0GTI4|A0A1B0GTI4_HUMAN,tr|A0A1C7CYY9|A0A1C7CYY9_HUMAN,tr|A0A1B0GU81|A0A1B0GU81_HUMAN,tr|A0A590UJK2|A0A590UJK2_HUMAN,tr|B5TYJ1|B5TYJ1_HUMAN,tr|A0A1B0GTW2|A0A1B0GTW2_HUMAN,tr|A0A384DVW2|A0A384DVW2_HUMAN,tr|A0A1B0GTN7|A0A1B0GTN7_HUMAN,tr|A0A087WW63|A0A087WW63_HUMAN,tr|A0A1B0GU74|A0A1B0GU74_HUMAN,tr|A0A1B0GUS3|A0A1B0GUS3_HUMAN" 12 936.5596 - 28349 11440 2 936.559779 469.2871 Voltage-dependent P\Q-type calcium channel subunit alpha-1A OS=Homo sapiens OX=9606 GN=CACNA1A PE=1 SV=3 11 2704.1 - 1.42E+06 - - - 0.1762 - 1.116 0.03 - 94.9 3 2 0 0.0002 8 0 0 0 - - - - - -0.6196 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.11451.11451.3 0.000222 Oct-52 K.SQIHDIVLVGGSTR.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1480.7998 41.13 28352 11451 3 1480.803596 494.6072 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2705.7 - 222604 - - - 2.5696 - 2.105 0.404 - 109.8 1 2 0 0.0038 14 0 0 0 1.31E+07 3.17E+05 - - - 5.0212 0.991 230117_WJC_METTL3_WT_vs_EV_F04.11453.11453.2 0.594 14-Jul R.GLGGIMVK.R sp|O94776|MTA2_HUMAN 1 773.4469 1.23 28353 11453 2 773.447008 387.7307 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 2705.9 - 843449 - - - 0.0802 - 1.128 0.188 - 127.2 1 2 0 0.0001 8 0 0 0 4.37E+07 3.56E+07 - - - 0.7928 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.11478.11478.2 0.768 14-Jun R.VILPDDVR.D "sp|Q3YEC7|RABL6_HUMAN,tr|F2Z2T0|F2Z2T0_HUMAN,tr|H0Y7H6|H0Y7H6_HUMAN,tr|G3V154|G3V154_HUMAN" 4 925.5233 104.8 28359 11478 2 925.523743 463.7689 Rab-like protein 6 OS=Homo sapiens OX=9606 GN=RABL6 PE=1 SV=2 4.21 2709.6 - 1.12E+06 - - - 0.4981 - 1.25 0.262 - 73 1 2 0 0.0005 8 0 0 0 4.61E+07 4.40E+05 - - - 1.649 0.9574 230117_WJC_METTL3_WT_vs_EV_F04.11488.11488.2 4.37 12-Sep K.LAPFIAK.R "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN,tr|K7ELX4|K7ELX4_HUMAN" 3 758.4691 1.61 28363 11488 2 758.46842 380.2418 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 8.75 2710.9 - 1.66E+06 - - - -0.8451 - 1.201 0.062 - 172.5 1 2 0 -0.0006 7 0 0 0 3.40E+08 2.11E+08 - - - 0.0791 0.9717 230117_WJC_METTL3_WT_vs_EV_F04.11502.11502.3 0.299 Jul-40 K.IWHHTFYNELR.V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1514.7419 1.99 28364 11502 3 1514.74341 505.9212 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2713.2 - 167317 - - - 1.0088 - 1.259 0.148 - 59.9 1 2 0 0.0015 11 0 0 0 1.01E+07 5.08E+06 - - - 0.8439 0.9337 230117_WJC_METTL3_WT_vs_EV_F04.11512.11512.2 12.4 12-Jun K.LAPFIAK[136.11].R "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN,tr|K7ELX4|K7ELX4_HUMAN" 3 766.4833 1.63 28366 11512 2 766.483931 384.2489 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 8.75 2714.7 - 1.17E+06 - - - 0.8741 - 1.192 0 - 91.5 6 2 0 0.0007 7 0 0 0 3.36E+08 2.07E+08 - - - -0.7503 0.9945 230117_WJC_METTL3_WT_vs_EV_F04.11536.11536.2 0.668 14-Sep R.TIAPIIGR.T sp|Q99459|CDC5L_HUMAN 1 839.5229 1.12 28375 11536 2 839.522379 420.7687 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.41 2718 - 291621 - - - -0.6063 - 1.439 0.183 - 246.1 1 2 0 -0.0005 8 0 0 0 1.92E+07 1.72E+07 - - - 1.4901 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.11544.11544.2 0.00127 18-Jun R.YSGSYNDYLR.A sp|Q96PK6|RBM14_HUMAN 1 1236.5411 2.59 28378 11544 2 1236.543194 619.2778 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.83 2719.1 - 89527.7 - - - 1.6797 - 1.246 0.434 - 63.9 1 2 0 0.0021 10 0 0 0 1.52E+06 5.85E+05 - - - 2.8598 0.8461 230117_WJC_METTL3_WT_vs_EV_F04.11546.11546.2 0.168 12-Jul R.KIELFGR.P sp|Q86U44|MTA70_HUMAN 1 861.5072 60.4 28379 11546 2 861.508056 431.7609 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2719.4 - 902346 - - - 0.9495 - 1.489 0.18 - 236.4 1 1 0 0.0008 7 0 0 0 1.19E+08 1.97E+06 - - - 1.6316 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.11550.11550.3 0.0774 Jul-40 K.IWHHTFYNELR[166.11].V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1524.7502 2.09 28382 11550 3 1524.751466 509.2573 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2719.8 - 103614 - - - 0.8618 - 1.55 0.235 - 44.1 1 2 0 0.0013 11 0 0 0 1.00E+07 4.79E+06 - - - 2.4047 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.11563.11563.2 0.0171 16-Sep R.LLSPLSSAR[166.11].L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 952.5581 1.06 28388 11563 2 952.55893 477.2863 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 2721.6 - 1.38E+06 - - - 0.8703 - 1.707 0.337 - 271.8 1 2 0 0.0008 9 0 0 0 1.75E+08 1.65E+08 - - - 3.0768 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.11566.11566.2 0.846 14-Sep R.TIAPIIGR[166.11].T sp|Q99459|CDC5L_HUMAN 1 849.5312 2.65 28391 11566 2 849.532069 425.7729 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.41 2721.9 - 553057 - - - 1.0724 - 1.48 0.241 - 275.4 1 2 0 0.0009 8 0 0 0 5.29E+07 2.00E+07 - - - 2.0031 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.11586.11586.2 0.0956 16-Oct R.LLSPLSSAR.L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 942.5498 1.08 28400 11586 2 942.550747 472.2822 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 2724.5 - 3.31E+06 - - - 0.9718 - 1.697 0.233 - 373.1 1 2 0 0.0009 9 0 0 0 1.75E+08 1.63E+08 - - - 2.2917 0.9569 230117_WJC_METTL3_WT_vs_EV_F04.11595.11595.2 1.95 14-Jun K.GLYPAPLK.L "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 857.5011 1.46 28403 11595 2 857.502491 429.7578 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.59 2725.8 - 568016 - - - 1.6338 - 0.947 0.115 - 110.8 3 2 0 0.0014 8 0 0 0 4.07E+07 2.79E+07 - - - -0.4874 0.9899 230117_WJC_METTL3_WT_vs_EV_F04.11598.11598.2 2.23 12-Jul K.IIVDELK[136.11].Q "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|H0Y9P0|H0Y9P0_HUMAN,tr|D6RF23|D6RF23_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 9 836.5099 1.04 28404 11598 2 836.510426 419.2622 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 4.37 2726.2 - 1.23E+06 - - - 0.6647 - 1.186 0.129 - 112.6 1 2 0 0.0006 7 0 0 0 5.94E+08 5.74E+08 - - - 0.5341 0.9972 230117_WJC_METTL3_WT_vs_EV_F04.11600.11600.2 0.0814 16-Oct R.LLPAELPAK[136.11].R sp|P78527|PRKDC_HUMAN 1 958.5943 1.22 28406 11600 2 958.599316 480.3044 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2726.3 - 562937 - - - 5.266 - 1.734 0.437 - 286 1 2 0 0.005 9 0 0 0 4.67E+07 3.82E+07 - - - 3.8595 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.11603.11603.2 0.351 12-Aug R.IDGVLIR.M sp|O75663|TIPRL_HUMAN 1 784.4807 2.44 28407 11603 2 784.481554 393.2476 TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2 5.84 2726.7 - 1.05E+06 - - - 1.1026 - 1.618 0.235 - 145.4 1 2 0 0.0009 7 0 0 0 6.91E+07 2.84E+07 - - - 2.3011 0.8542 230117_WJC_METTL3_WT_vs_EV_F04.11605.11605.2 0.0774 16-Jul N.LVIITAGAR[166.11].Q "sp|Q9BYZ2|LDH6B_HUMAN,sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 7 922.5839 0.97 28408 11605 2 922.585569 462.2992 L-lactate dehydrogenase A-like 6B OS=Homo sapiens OX=9606 GN=LDHAL6B PE=1 SV=3 9.75 2727 - 2.29E+06 - - - 1.7852 - 1.49 0.222 - 126.5 2 1 0 0.0016 9 0 0 0 1.53E+08 1.58E+08 - - - 1.6994 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.11607.11607.2 1.23E-05 12-Jul K.C[160.03]PVFVVR.W "sp|Q9C0J8|WDR33_HUMAN,tr|C9J8B4|C9J8B4_HUMAN" 2 875.4687 1.74 28409 11607 2 875.468643 438.7416 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 8.25 2727.2 - 551080 - - - -0.1154 - 1.663 0.471 - 235.5 1 2 0 -0.0001 7 0 0 0 9.55E+07 5.48E+07 - - - 4.1314 0.9892 230117_WJC_METTL3_WT_vs_EV_F04.11609.11609.2 0.243 12-Jul R.FPGAYLK.G "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 794.4327 1.26 28410 11609 2 794.435225 398.2236 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.59 2727.4 - 1.08E+06 - - - 3.2086 - 1.453 0.097 - 130.7 1 2 0 0.0025 7 0 0 0 1.37E+08 1.09E+08 - - - 0.9405 0.9916 230117_WJC_METTL3_WT_vs_EV_F04.11618.11618.2 0.364 12-Jul R.VAGIFPR[166.11].L "sp|O96005|CLPT1_HUMAN,tr|K7EJ16|K7EJ16_HUMAN" 2 768.4522 0.8 28413 11618 2 768.452381 385.2334 Cleft lip and palate transmembrane protein 1 OS=Homo sapiens OX=9606 GN=CLPTM1 PE=1 SV=1 9.72 2728.6 - 1.49E+06 - - - 0.2629 - 1.265 0.135 - 171.6 1 2 0 0.0002 7 0 0 0 5.35E+07 6.68E+07 - - - 0.7829 0.9868 230117_WJC_METTL3_WT_vs_EV_F04.11622.11622.2 0.481 12-Jun K.IIVDELK.Q "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|H0Y9P0|H0Y9P0_HUMAN,tr|D6RF23|D6RF23_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 9 828.4957 1.04 28415 11622 2 828.496806 415.2551 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 4.37 2729.2 - 8.14E+06 - - - 1.3712 - 1.403 0.041 - 103 2 2 0 0.0011 7 0 0 0 5.94E+08 5.74E+08 - - - 0.2819 0.998 230117_WJC_METTL3_WT_vs_EV_F04.11624.11624.2 0.00358 14-Aug R.FGPLASVK.L "sp|O15042|SR140_HUMAN,tr|E7EW00|E7EW00_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H0Y8D9|H0Y8D9_HUMAN" 4 817.4698 0.15 28416 11624 2 817.470588 409.7422 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 8.75 2729.4 - 2.11E+06 - - - 0.9762 - 1.734 0.142 - 192 1 2 0 0.0008 8 0 0 0 1.14E+08 7.64E+08 - - - 1.7496 0.947 230117_WJC_METTL3_WT_vs_EV_F04.11630.11630.2 6.79 12-Jul R.FPGAYLK[136.11].G "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 802.4469 1.5 28419 11630 2 802.449064 402.2307 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.59 2730.1 - 803065 - - - 2.7267 - 1.113 0.054 - 144.5 2 2 0 0.0022 7 0 0 0 8.04E+07 5.36E+07 - - - -0.3561 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.11638.11638.2 0.129 14-Sep K.LINAVELK.K sp|P56192|SYMC_HUMAN 1 898.5488 1.09 28424 11638 2 898.549724 450.2817 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6 2731.2 - 1.64E+06 - - - 1.0639 - 1.578 0.294 - 180.8 1 2 0 0.001 8 0 0 0 1.96E+08 1.80E+08 - - - 2.5879 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.11650.11650.2 0.0702 12-Jul K.LLQEIVR.S "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 869.5335 1.48 28427 11650 2 869.533422 435.774 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6 2732.9 - 1.87E+06 - - - -0.0345 - 1.463 0.277 - 175.7 1 2 0 0 7 0 0 0 6.77E+07 4.57E+07 - - - 2.2925 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.11660.11660.2 0.00821 20-Jul K.VLFSSNGGVVK[136.11].G "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 1113.6274 1.22 28431 11660 2 1113.627796 557.821 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.72 2734.3 - 145603 - - - 0.3924 - 1.398 0.418 - 94.7 1 2 0 0.0004 11 0 0 0 1.09E+07 8.94E+06 - - - 3.0346 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.11663.11663.2 0.0186 14-Aug K.MVSAAFMK.K "sp|P25205|MCM3_HUMAN,tr|Q7Z6P5|Q7Z6P5_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 4 883.4296 2.91 28432 11663 2 883.430014 442.7221 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 8.5 2734.6 - 1.41E+06 - - - 0.4901 - 1.403 0.298 - 221.8 1 2 0 0.0004 8 0 0 0 4.75E+07 1.63E+07 - - - 2.2631 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.11667.11667.2 0.0531 14-Jul R.MVLVGDVK[136.11].D "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PEU0|A0A6Q8PEU0_HUMAN,tr|A0A6Q8PHI4|A0A6Q8PHI4_HUMAN,tr|A0A6Q8PG82|A0A6Q8PG82_HUMAN" 7 867.4979 2.05 28434 11667 2 867.49821 434.7562 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 5.59 2735.2 - 1.28E+06 - - - 0.3285 - 1.624 0.315 - 194.7 1 2 0 0.0003 8 0 0 0 2.33E+08 1.14E+08 - - - 2.8299 1 230117_WJC_METTL3_WT_vs_EV_F04.11672.11672.3 9.98E-11 15/84 K.DHTPSQELALTQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2270.0411 999 28436 11672 3 2270.043178 757.6876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2735.9 - 154251 - - - 0.9167 - 3.559 0.668 - 203.1 1 2 0 0.0021 22 0 0 0 4.97E+06 0.00E+00 - - - 8.9967 0.996 230117_WJC_METTL3_WT_vs_EV_F04.11674.11674.2 0.316 14-Aug R.LLGQIVDR[166.11].C sp|Q96I24|FUBP3_HUMAN 1 922.5475 1.46 28437 11674 2 922.548491 462.281 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2736.1 - 1.18E+06 - - - 1.0352 - 1.369 0.158 - 187.5 1 2 0 0.001 8 0 0 0 1.22E+09 8.33E+08 - - - 1.1549 0.9889 230117_WJC_METTL3_WT_vs_EV_F04.11675.11675.2 0.385 14-Jul K.NIILGGVK.A "sp|P22314|UBA1_HUMAN,tr|Q5JRS3|Q5JRS3_HUMAN,tr|Q5JRS2|Q5JRS2_HUMAN,tr|Q5JRS0|Q5JRS0_HUMAN,tr|Q5JRS1|Q5JRS1_HUMAN,tr|Q5JRR9|Q5JRR9_HUMAN" 6 812.512 2.3 28438 11675 2 812.513052 407.2633 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 8.75 2736.2 - 247421 - - - 1.3083 - 1.403 0.045 - 120.1 1 2 0 0.0011 8 0 0 0 3.74E+07 1.63E+07 - - - 0.3943 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.11676.11676.2 0.143 14-Aug K.LINAVELK[136.11].K sp|P56192|SYMC_HUMAN 1 906.563 1.09 28439 11676 2 906.564066 454.2888 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6 2736.3 - 3.98E+06 - - - 1.2112 - 1.635 0.218 - 157.5 1 2 0 0.0011 8 0 0 0 1.96E+08 1.80E+08 - - - 2.1336 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.11692.11692.2 0.002 16-Sep K.NDLAVVDVR[166.11].L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1009.5432 0.73 28443 11692 2 1009.546134 505.7789 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.21 2738.7 - 375352 - - - 2.9271 - 1.651 0.415 - 361.8 1 2 0 0.003 9 0 0 0 1.52E+07 2.09E+07 - - - 3.5558 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.11711.11711.2 0.106 14-Sep R.LLGQIVDR.C sp|Q96I24|FUBP3_HUMAN 1 912.5393 1.46 28452 11711 2 912.540764 457.2769 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2741.2 - 1.49E+07 - - - 1.6416 - 1.608 0.327 - 234.5 1 2 0 0.0015 8 0 0 0 1.22E+09 8.34E+08 - - - 2.8883 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.11716.11716.2 0.0127 20-Jul K.LLAETVAPAVR[166.11].G "sp|Q9BSJ8|ESYT1_HUMAN,tr|F8VZB1|F8VZB1_HUMAN" 2 1148.6793 0.38 28454 11716 2 1148.677858 575.3469 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6 2741.8 - 172928 - - - -1.2371 - 1.592 0.336 - 133 1 2 0 -0.0014 11 0 0 0 7.11E+06 1.88E+07 - - - 2.7802 0.9945 230117_WJC_METTL3_WT_vs_EV_F04.11720.11720.2 0.0547 16-Apr K.SC[160.03]AHDWVYE.- "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 3 1165.4499 - 28456 11720 2 1165.451684 583.7322 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 4.71 2742.2 - 46191.6 - - - 1.5659 - 0.874 0.306 - 45.4 1 2 0 0.0018 9 0 0 0 - - - - - 0.9109 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.11731.11731.2 0.0375 14-Oct R.LGMGLVSR.S "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 831.4637 1.47 28459 11731 2 831.46472 416.7391 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 9.75 2743.8 - 941927 - - - 1.2773 - 2.34 0.365 - 293.7 1 2 0 0.0011 8 0 0 0 6.30E+07 4.30E+07 - - - 4.3006 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.11744.11744.3 0.00266 Oct-40 K.HFSGLEEAVYR.N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1306.6306 20.71 28462 11744 3 1306.632793 436.5508 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 2745.8 - 218806 - - - 1.6784 - 1.864 0.362 - 141.1 1 2 0 0.0022 11 0 0 0 1.73E+07 8.34E+05 - - - 4.3444 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.11750.11750.2 0.000424 20-Oct K.LLAETVAPAVR.G "sp|Q9BSJ8|ESYT1_HUMAN,tr|F8VZB1|F8VZB1_HUMAN" 2 1138.671 0.42 28463 11750 2 1138.675308 570.3428 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6 2746.7 - 362844 - - - 3.7755 - 1.848 0.413 - 328.4 1 2 0 0.0043 11 0 0 0 7.11E+06 1.69E+07 - - - 3.7514 0.9907 230117_WJC_METTL3_WT_vs_EV_F04.11755.11755.2 0.0666 18-Jun K.FGEVVDC[160.03]TIK.M "sp|Q99729|ROAA_HUMAN,sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 13 1166.5642 0.29 28465 11755 2 1166.563949 584.2894 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 4.37 2747.3 - 73608.1 - - - -0.1817 - 1.269 0.158 - 106.9 1 2 0 -0.0002 10 0 0 0 1.74E+06 6.02E+06 - - - 0.8729 0.9821 230117_WJC_METTL3_WT_vs_EV_F04.11764.11764.2 0.826 12-Jun R.SIFDHIK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 858.46 0.86 28470 11764 2 858.461104 430.2373 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.46 2748.3 - 771624 - - - 1.3408 - 0.986 0.146 - 114.6 1 2 0 0.0012 7 0 0 0 4.08E+07 4.74E+07 - - - 0.0743 0.9099 230117_WJC_METTL3_WT_vs_EV_F04.11769.11769.2 1.09 12-Jul R.VIEVLPR.G sp|Q99611|SPS2_HUMAN 1 824.512 18.91 28471 11769 2 824.510457 413.2633 "Selenide, water dikinase 2 OS=Homo sapiens OX=9606 GN=SEPHS2 PE=1 SV=3" 5.97 2749.1 - 465431 - - - -1.8581 - 1.122 0.078 - 122.5 1 2 0 -0.0015 7 0 0 0 2.44E+07 1.29E+06 - - - -0.0186 0.9853 230117_WJC_METTL3_WT_vs_EV_F04.11771.11771.2 0.95 12-Jun R.SIFDHIK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 866.4742 0.92 28472 11771 2 866.475879 434.2444 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.46 2749.3 - 992912 - - - 1.992 - 0.907 0.209 - 96.3 1 2 0 0.0017 7 0 0 0 4.06E+07 4.43E+07 - - - 0.2748 0.8479 230117_WJC_METTL3_WT_vs_EV_F04.11772.11772.2 3.88 20-Apr K.HFSGLEEAVYR.N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1306.6306 3.18 28473 11772 2 1306.633419 654.3226 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 2749.5 - 135675 - - - 2.1575 - 1.068 0 - 32.7 11 2 0 0.0028 11 0 0 0 5.81E+06 1.83E+06 - - - -1.2471 1 230117_WJC_METTL3_WT_vs_EV_F04.11775.11775.3 1.39E-08 15/68 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 2.28 28474 11775 3 2070.869092 691.296 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2749.9 - 149518 - - - 1.3521 - 3.159 0.724 - 261.4 1 2 0 0.0028 18 0 0 0 5.55E+06 2.44E+06 - - - 9.4754 0.9934 230117_WJC_METTL3_WT_vs_EV_F04.11777.11777.2 1.54 12-Jun R.VVVEYLR.A sp|O60645|EXOC3_HUMAN 1 876.5069 1.37 28475 11777 2 876.508525 439.2607 Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3 5.97 2750.1 - 244384 - - - 1.8505 - 1.287 0.132 - 106.1 1 2 0 0.0016 7 0 0 0 2.76E+07 2.02E+07 - - - 0.8149 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.11778.11778.2 0.0245 20-Nov R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 0.89 28476 11778 2 1166.704211 584.3584 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2750.2 - 321049 - - - 1.6302 - 2.089 0.273 - 388.2 1 2 0 0.0019 11 0 0 0 4.05E+07 4.53E+07 - - - 3.0497 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.11781.11781.2 0.0243 20-Nov R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 0.89 28477 11781 2 1174.7188 588.3655 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2750.7 - 960430 - - - 1.9503 - 2.122 0.367 - 319.8 1 2 0 0.0023 11 0 0 0 4.03E+07 4.53E+07 - - - 3.7863 0.9629 230117_WJC_METTL3_WT_vs_EV_F04.11782.11782.2 0.00987 16-Sep L.ASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 940.5342 1 28478 11782 2 940.534353 471.2744 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 2750.8 - 290258 - - - 0.1829 - 1.873 0.391 - 279.9 1 1 0 0.0002 9 0 0 0 1.55E+07 1.55E+07 - - - 3.7444 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.11783.11783.3 0.00719 14/40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 0.77 28479 11783 3 1174.718042 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2750.8 - 5.19E+06 - - - 1.305 - 2.565 0.142 - 155.2 1 2 0 0.0015 11 0 0 0 1.80E+08 2.32E+08 - - - 2.7987 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.11784.11784.3 0.000829 15/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 0.78 28480 11784 3 1166.704443 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2750.9 - 3.58E+06 - - - 1.8291 - 2.533 0.241 - 185 1 2 0 0.0021 11 0 0 0 1.80E+08 2.32E+08 - - - 3.8666 0.8964 230117_WJC_METTL3_WT_vs_EV_F04.11786.11786.2 0.0298 18-Oct L.LASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1053.6182 0.74 28482 11786 2 1053.622309 527.8164 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2751.1 - 204626 - - - 3.8572 - 2.025 0.318 - 261.9 1 1 0 0.0041 10 0 0 0 7.01E+06 9.51E+06 - - - 3.3579 0.9694 230117_WJC_METTL3_WT_vs_EV_F04.11797.11797.2 0.0161 16-Oct L.ASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 948.5484 0.99 28489 11797 2 948.549449 475.2815 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 2752.6 - 1.45E+06 - - - 1.1259 - 2.068 0.331 - 493.5 1 1 0 0.0011 9 0 0 0 1.54E+07 1.55E+07 - - - 3.5875 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.11798.11798.2 0.000136 12-Aug R.VFVVMEK.L "sp|Q15139|KPCD1_HUMAN,sp|O94806|KPCD3_HUMAN,sp|Q9BZL6|KPCD2_HUMAN,tr|M0R2Z8|M0R2Z8_HUMAN,tr|F8WBA3|F8WBA3_HUMAN" 5 850.4623 0.11 28490 11798 2 850.462849 426.2384 Serine\threonine-protein kinase D1 OS=Homo sapiens OX=9606 GN=PRKD1 PE=1 SV=2 5.97 2752.7 - 200505 - - - 0.6914 - 1.711 0.27 - 188.3 1 2 0 0.0006 7 0 0 0 1.18E+07 1.08E+08 - - - 2.7368 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.11799.11799.2 0.0166 16-Jun K.ESYSVYVYK[136.11].V "sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 10 1144.5532 1.56 28491 11799 2 1144.555189 573.2839 Histone H2B type 2-F OS=Homo sapiens OX=9606 GN=H2BC18 PE=1 SV=3 6.1 2752.8 - 95634.5 - - - 1.7457 - 1.101 0.345 - 94.9 1 2 0 0.002 9 0 0 0 6.23E+06 4.00E+06 - - - 1.8669 0.9961 230117_WJC_METTL3_WT_vs_EV_F04.11805.11805.2 0.058 12-Jul K.LDPVLYR.K "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 874.4913 0.89 28494 11805 2 874.493384 438.2529 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 5.84 2753.5 - 717769 - - - 2.4368 - 1.532 0.135 - 204.5 1 2 0 0.0021 7 0 0 0 9.96E+07 1.11E+08 - - - 1.3891 0.9949 230117_WJC_METTL3_WT_vs_EV_F04.11807.11807.2 0.214 24-Jun R.SILSPGGSC[160.03]GPIK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1279.6686 0.98 28496 11807 2 1279.670217 640.8416 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 7.94 2753.7 - 92206.1 - - - 1.2847 - 1.368 0.151 - 77.1 1 2 0 0.0016 13 0 0 0 3.99E+06 4.06E+06 - - - 0.96 0.9949 230117_WJC_METTL3_WT_vs_EV_F04.11822.11822.2 0.0129 12-Jun K.LDPVLYR[166.11].K "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 884.4995 0.91 28503 11822 2 884.501059 443.257 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 5.84 2755.8 - 2.68E+06 - - - 1.7366 - 1.233 0.173 - 135.7 1 2 0 0.0015 7 0 0 0 1.02E+08 1.12E+08 - - - 0.982 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.11823.11823.2 0.64 16-Oct K.VGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 911.5804 2.01 28504 11823 2 911.581647 456.7975 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2755.9 - 1.09E+06 - - - 1.3647 - 2.076 0.225 - 223.4 1 2 0 0.0012 9 0 0 0 6.33E+08 3.14E+08 - - - 2.8157 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.11827.11827.2 0.00925 16-Nov K.VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 919.5946 2.01 28506 11827 2 919.595156 460.8046 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2756.4 - 1.02E+06 - - - 0.6014 - 2.47 0.272 - 354.5 1 2 0 0.0006 9 0 0 0 6.33E+08 3.14E+08 - - - 3.6658 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.11828.11828.2 1.8 12-Aug K.LEDLIVK[136.11].D "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 836.5099 1.99 28507 11828 2 836.509919 419.2622 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2756.5 - 1.24E+06 - - - 0.0586 - 1.892 0.13 - 154.6 1 2 0 0 7 0 0 0 1.19E+09 5.98E+08 - - - 2.0215 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.11840.11840.2 0.028 18-Jul K.YEELQVTVGR.H sp|P35908|K22E_HUMAN 1 1192.6088 27.58 28513 11840 2 1192.613515 597.3117 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.53 2758.1 - 91284.5 - - - 3.9518 - 1.611 0.346 - 168.8 1 2 0 0.0047 10 0 0 0 2.38E+06 8.63E+04 - - - 2.9261 0.9517 230117_WJC_METTL3_WT_vs_EV_F04.11844.11844.2 6.83 12-Jun R.LLLPGTR.A sp|Q6P087|RUSD3_HUMAN 1 768.4858 1.48 28514 11844 2 768.486298 385.2502 Mitochondrial mRNA pseudouridine synthase RPUSD3 OS=Homo sapiens OX=9606 GN=RPUSD3 PE=1 SV=3 9.75 2758.6 - 701156 - - - 0.6819 - 1.173 0.039 - 122.7 6 2 0 0.0005 7 0 0 0 3.90E+07 2.63E+07 - - - -0.5131 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.11848.11848.2 0.011 18-Aug K.LITPAVVSER[166.11].L sp|P62851|RS25_HUMAN 1 1093.6371 1.06 28516 11848 2 1093.636706 547.8258 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 6 2759.2 - 251429 - - - -0.3411 - 1.6 0.335 - 211.6 1 2 0 -0.0004 10 0 0 0 9.70E+06 9.18E+06 - - - 2.8271 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.11850.11850.2 0.9 12-Sep K.LEDLIVK.D "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 828.4957 1.99 28517 11850 2 828.496368 415.2551 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2759.4 - 1.39E+07 - - - 0.8425 - 2.004 0.063 - 262.3 1 2 0 0.0007 7 0 0 0 1.19E+09 5.98E+08 - - - 1.7087 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.11852.11852.2 1.13 12-Aug R.LGLTEIR[166.11].K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 810.4839 1.18 28518 11852 2 810.484143 406.2492 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2759.6 - 2.11E+06 - - - 0.3331 - 1.691 0.145 - 199.3 1 2 0 0.0003 7 0 0 0 9.16E+08 7.74E+08 - - - 1.7764 0.9941 230117_WJC_METTL3_WT_vs_EV_F04.11857.11857.2 2.17 12-Jul R.LGLTEIR.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 800.4756 1.18 28521 11857 2 800.475579 401.2451 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2760.3 - 3.44E+06 - - - -0.03 - 1.501 0.113 - 146.6 1 2 0 0 7 0 0 0 9.16E+08 7.74E+08 - - - 1.1625 0.9772 230117_WJC_METTL3_WT_vs_EV_F04.11859.11859.2 1.1 12-Jul K.FLEATLR.S "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN" 2 848.4756 0.73 28523 11859 2 848.47362 425.2451 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 6 2760.5 - 326504 - - - -2.3371 - 1.507 0.119 - 161 1 2 0 -0.002 7 0 0 0 3.12E+07 4.27E+07 - - - 1.2188 0.9661 230117_WJC_METTL3_WT_vs_EV_F04.11863.11863.2 2.24 12-Jun R.LLLPGTR[166.11].A sp|Q6P087|RUSD3_HUMAN 1 778.494 1.58 28525 11863 2 778.49468 390.2543 Mitochondrial mRNA pseudouridine synthase RPUSD3 OS=Homo sapiens OX=9606 GN=RPUSD3 PE=1 SV=3 9.75 2761.1 - 663530 - - - 0.817 - 1.274 0.003 - 109.9 2 2 0 0.0006 7 0 0 0 3.80E+07 2.41E+07 - - - -0.3042 0.9824 230117_WJC_METTL3_WT_vs_EV_F04.11864.11864.2 0.412 12-Jun K.FLEATLR[166.11].S "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN" 2 858.4839 0.73 28526 11864 2 858.486325 430.2492 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 6 2761.2 - 747722 - - - 2.8562 - 1.182 0.117 - 113.4 1 2 0 0.0025 7 0 0 0 3.12E+07 4.28E+07 - - - 0.4342 0.9847 230117_WJC_METTL3_WT_vs_EV_F04.11888.11888.2 1.1 12-May K.LLSTFPR[166.11].R "sp|Q9UNN5|FAF1_HUMAN,tr|B3KT28|B3KT28_HUMAN,tr|B1ANM7|B1ANM7_HUMAN" 3 842.489 1.22 28534 11888 2 842.488873 422.2518 FAS-associated factor 1 OS=Homo sapiens OX=9606 GN=FAF1 PE=1 SV=2 9.75 2764.4 - 495697 - - - -0.1021 - 1.039 0.197 - 47.6 2 2 0 -0.0001 7 0 0 0 7.19E+07 5.91E+07 - - - 0.4828 0.9674 230117_WJC_METTL3_WT_vs_EV_F04.11889.11889.2 0.283 12-May K.LMPTQWR.T sp|Q99459|CDC5L_HUMAN 1 930.4746 1.1 28535 11889 2 930.473738 466.2446 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.75 2764.6 - 467821 - - - -0.8802 - 1.005 0.202 - 82.2 4 2 0 -0.0008 7 0 0 0 3.98E+07 3.61E+07 - - - 0.2796 0.9945 230117_WJC_METTL3_WT_vs_EV_F04.11896.11896.2 0.243 14-Jul K.LIEQYALR.E sp|Q9NUQ3|TXLNG_HUMAN 1 1004.5655 1.47 28539 11896 2 1004.565707 503.29 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2765.4 - 520356 - - - 0.225 - 1.36 0.155 - 145.6 1 2 0 0.0002 8 0 0 0 3.57E+07 2.43E+07 - - - 1.1131 0.997 230117_WJC_METTL3_WT_vs_EV_F04.11899.11899.2 0.999 14-Aug K.LIEQYALR[166.11].E sp|Q9NUQ3|TXLNG_HUMAN 1 1014.5738 1.47 28540 11899 2 1014.575765 508.2942 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2765.8 - 406523 - - - 1.9851 - 1.493 0.165 - 199.9 1 2 0 0.002 8 0 0 0 3.57E+07 2.43E+07 - - - 1.4678 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.11903.11903.2 0.0989 12-Jun K.AFMGPLK.K "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN" 2 762.4098 0.9 28542 11903 2 762.410172 382.2122 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 8.8 2766.4 - 828554 - - - 0.446 - 1.154 0.28 - 148.6 1 2 0 0.0003 7 0 0 0 4.70E+07 5.21E+07 - - - 1.5628 0.9449 230117_WJC_METTL3_WT_vs_EV_F04.11913.11913.2 1.99 12-Jun R.IGNFIVK.K "sp|Q00796|DHSO_HUMAN,tr|H0YKB3|H0YKB3_HUMAN,tr|A0A6I8PIS1|A0A6I8PIS1_HUMAN" 3 789.4749 30.28 28547 11913 2 789.474404 395.7447 Sorbitol dehydrogenase OS=Homo sapiens OX=9606 GN=SORD PE=1 SV=4 8.75 2767.6 - 624731 - - - -0.5966 - 1.056 0.127 - 68.1 6 2 0 -0.0005 7 0 0 0 2.92E+07 9.65E+05 - - - -0.1961 0.9917 230117_WJC_METTL3_WT_vs_EV_F04.11955.11955.2 0.676 12-Aug K.FVNLYTR.E "sp|Q15650|TRIP4_HUMAN,tr|H0YL91|H0YL91_HUMAN" 2 911.4865 1.88 28563 11955 2 911.485823 456.7505 Activating signal cointegrator 1 OS=Homo sapiens OX=9606 GN=TRIP4 PE=1 SV=4 8.75 2773.3 - 228344 - - - -0.7449 - 1.419 0.146 - 160.2 1 2 0 -0.0007 7 0 0 0 2.22E+07 1.18E+07 - - - 1.228 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.11956.11956.2 0.049 24-Aug R.GGIGAGLGGGLC[160.03]R.R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1143.5819 0.63 28564 11956 2 1143.582559 572.7982 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2773.4 - 186420 - - - 0.5972 - 1.498 0.285 - 118.5 1 2 0 0.0007 13 0 0 0 9.71E+06 1.54E+07 - - - 2.183 0.9892 230117_WJC_METTL3_WT_vs_EV_F04.11963.11963.2 0.139 12-Jul R.FALVTPK.K sp|P49792|RBP2_HUMAN 1 774.464 0.46 28566 11963 2 774.464376 388.2393 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.75 2774.5 - 372384 - - - 0.5165 - 1.404 0.055 - 178.7 1 2 0 0.0004 7 0 0 0 5.29E+07 1.14E+08 - - - 0.5223 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.11964.11964.2 0.0944 14/24 R.GGIGAGLGGGLC[160.03]R[166.11].R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1153.5901 0.63 28567 11964 2 1153.592377 577.8023 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2774.6 - 287128 - - - 1.934 - 2.103 0.348 - 484.4 1 2 0 0.0022 13 0 0 0 9.65E+06 1.54E+07 - - - 3.5185 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.11969.11969.2 0.246 16-Jun R.LITGLGVGR[166.11].E sp|Q9BQG0|MBB1A_HUMAN 1 894.5526 1.17 28570 11969 2 894.553285 448.2836 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 9.75 2775.2 - 376632 - - - 0.7423 - 1.335 0.251 - 70.4 1 2 0 0.0007 9 0 0 0 1.25E+08 1.07E+08 - - - 1.7306 0.9931 230117_WJC_METTL3_WT_vs_EV_F04.11982.11982.2 0.233 12-May R.AAYIYIR[166.11].G "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|B4DE93|B4DE93_HUMAN,tr|E9PJL9|E9PJL9_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PLC6|E9PLC6_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN" 8 878.489 5.1 28576 11982 2 878.489705 440.2518 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.63 2777.1 - 264931 - - - 0.8492 - 1.082 0.201 - 79.3 1 2 0 0.0007 7 0 0 0 1.10E+08 2.16E+07 - - - 0.7751 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.11997.11997.2 0.00222 20-Aug K.LATNAAVTVLR.V "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1127.6663 80.32 28582 11997 2 1127.669963 564.8404 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 9.75 2779.2 - 121061 - - - 3.2855 - 1.965 0.235 - 202.9 1 2 0 0.0037 11 0 0 0 6.98E+06 8.69E+04 - - - 2.6029 0.994 230117_WJC_METTL3_WT_vs_EV_F04.12001.12001.2 0.384 12-Jul K.ILLVDER.S "sp|A5YKK6|CNOT1_HUMAN,tr|H3BMZ2|H3BMZ2_HUMAN" 2 856.5018 1.13 28585 12001 2 856.504811 429.2582 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.37 2779.6 - 827174 - - - 3.4944 - 1.475 0.174 - 161.1 1 2 0 0.003 7 0 0 0 7.25E+07 6.41E+07 - - - 1.5567 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.12006.12006.2 0.000228 16-Sep R.LITGLGVGR.E sp|Q9BQG0|MBB1A_HUMAN 1 884.5444 1.15 28588 12006 2 884.544664 443.2795 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 9.75 2780.2 - 2.68E+06 - - - 0.3539 - 1.682 0.462 - 170 1 2 0 0.0003 9 0 0 0 1.24E+08 1.07E+08 - - - 3.9576 0.9231 230117_WJC_METTL3_WT_vs_EV_F04.12012.12012.2 5.43 12-Jun R.FALVTPK[136.11].K sp|P49792|RBP2_HUMAN 1 782.4782 0.98 28590 12012 2 782.477927 392.2464 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.75 2781 - 827267 - - - -0.3182 - 1.145 0.061 - 86 10 2 0 -0.0002 7 0 0 0 4.81E+07 4.91E+07 - - - -0.5262 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.12021.12021.2 0.117 14-Aug K.ILVDALQK.F "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 15 898.5488 1.07 28595 12021 2 898.550452 450.2817 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 5.84 2782.1 - 652142 - - - 1.8741 - 1.564 0.3 - 125.4 1 2 0 0.0017 8 0 0 0 6.14E+07 5.74E+07 - - - 2.6051 0.9924 230117_WJC_METTL3_WT_vs_EV_F04.12025.12025.2 0.296 14-Jul R.ALLGPALK.D sp|P35250|RFC2_HUMAN 1 781.5062 1.89 28596 12025 2 781.505472 391.7604 Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3 8.8 2782.7 - 1.44E+06 - - - -0.8995 - 1.408 0.176 - 153.3 1 2 0 -0.0007 8 0 0 0 1.01E+08 5.35E+07 - - - 1.3727 0.998 230117_WJC_METTL3_WT_vs_EV_F04.12035.12035.2 0.117 12-Jun K.VPVNLLR[166.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 819.5206 1.17 28601 12035 2 819.520136 410.7676 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2783.8 - 428642 - - - -0.5576 - 1.374 0.321 - 220.8 1 2 0 -0.0005 7 0 0 0 1.43E+08 1.22E+08 - - - 2.4185 0.9891 230117_WJC_METTL3_WT_vs_EV_F04.12038.12038.2 0.702 12-Aug K.LTELLVK.A "sp|O95470|SGPL1_HUMAN,tr|H0Y3V8|H0Y3V8_HUMAN,tr|H7BXL7|H7BXL7_HUMAN" 3 814.5164 2.69 28602 12038 2 814.514924 408.2655 Sphingosine-1-phosphate lyase 1 OS=Homo sapiens OX=9606 GN=SGPL1 PE=1 SV=3 6 2784.2 - 440985 - - - -1.8183 - 1.424 0.19 - 147.9 1 2 0 -0.0015 7 0 0 0 7.34E+07 2.73E+07 - - - 1.5639 0.993 230117_WJC_METTL3_WT_vs_EV_F04.12040.12040.2 0.682 12-Jun K.VPVNLLR.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 809.5123 1.17 28604 12040 2 809.512343 405.7634 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2784.4 - 661359 - - - 0.0247 - 1.208 0.184 - 125 1 2 0 0 7 0 0 0 1.43E+08 1.22E+08 - - - 0.9988 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.12044.12044.2 0.457 14-Aug K.ILVDALQK[136.11].F "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 15 906.563 1.07 28606 12044 2 906.563997 454.2888 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 5.84 2784.9 - 1.51E+06 - - - 1.1351 - 1.473 0.183 - 181.5 1 2 0 0.001 8 0 0 0 6.14E+07 5.75E+07 - - - 1.5604 1 230117_WJC_METTL3_WT_vs_EV_F04.12048.12048.2 0.000325 14/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 28608 12048 2 1302.608599 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2785.5 - 3.76E+06 - - - -0.4583 - 2.404 0.522 - 421 1 2 0 -0.0006 13 0 0 0 1.74E+09 0.00E+00 - - - 5.1475 0.9963 230117_WJC_METTL3_WT_vs_EV_F04.12058.12058.2 0.0685 12-Jul K.IDPLLPK.E sp|Q9BYD6|RM01_HUMAN 1 794.4902 2.57 28612 12058 2 794.489569 398.2524 "39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2" 5.84 2786.7 - 1.53E+06 - - - -0.7829 - 1.408 0.246 - 135.4 1 2 0 -0.0006 7 0 0 0 2.45E+08 9.53E+07 - - - 1.9419 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.12060.12060.2 2.38E-05 20-Sep R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 7925.43 28613 12060 2 1201.607985 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2786.9 - 1.68E+06 - - - -0.9587 - 1.958 0.448 - 95.9 1 2 0 -0.0012 11 0 0 0 6.48E+09 8.18E+05 - - - 4.1673 0.9961 230117_WJC_METTL3_WT_vs_EV_F04.12088.12088.2 0.00167 12-Aug R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.92 28623 12088 2 852.482475 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2790.8 - 1.68E+07 - - - -1.3842 - 1.315 0.319 - 200.2 1 2 0 -0.0012 7 0 0 0 1.98E+09 1.03E+09 - - - 2.2644 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.12097.12097.3 0.00364 Dec-40 R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 1277.12 28627 12097 3 1201.609195 401.5437 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2791.8 - 2.16E+06 - - - 0.0483 - 2.027 0.221 - 208.8 1 2 0 0.0001 11 0 0 0 3.82E+08 2.99E+05 - - - 3.0111 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.12098.12098.2 0.269 14-Jul K.ILFTEATR.L "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 949.5233 1.66 28628 12098 2 949.523783 475.7689 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 6 2791.9 - 1.04E+06 - - - 0.5276 - 1.405 0.309 - 159 1 2 0 0.0005 8 0 0 0 4.27E+07 2.56E+07 - - - 2.3487 0.9021 230117_WJC_METTL3_WT_vs_EV_F04.12099.12099.2 0.00109 18-Aug R.LVHPGVAEVV.F "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1018.5811 - 28629 12099 2 1018.581416 510.2978 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.24 2792 - 472621 - - - 0.2798 - 1.503 0.29 - 132.6 1 1 0 0.0003 10 0 0 0 - - - - - 2.3202 0.9937 230117_WJC_METTL3_WT_vs_EV_F04.12106.12106.2 0.504 14-Sep R.TFGVSPLR.R sp|Q5T750|XP32_HUMAN 1 875.4865 50.23 28631 12106 2 875.489544 438.7505 Skin-specific protein 32 OS=Homo sapiens OX=9606 GN=XP32 PE=1 SV=1 9.41 2793.1 - 832505 - - - 3.4746 - 1.272 0.236 - 203.8 1 2 0 0.003 8 0 0 0 8.36E+07 1.66E+06 - - - 1.5088 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.12117.12117.2 0.00717 12-Jul R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.45 28635 12117 2 844.469562 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2794.7 - 2.75E+07 - - - 0.1267 - 1.452 0.271 - 144.1 1 2 0 0.0001 7 0 0 0 1.04E+10 7.17E+09 - - - 2.2243 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.12130.12130.2 0.831 12-Jul K.MLEYALK.Q "sp|Q13033|STRN3_HUMAN,sp|Q9NRL3|STRN4_HUMAN,sp|O43815|STRN_HUMAN,tr|M0R0P4|M0R0P4_HUMAN,tr|G3V3G7|G3V3G7_HUMAN,tr|F5GYK2|F5GYK2_HUMAN,tr|M0R2A7|M0R2A7_HUMAN,tr|M0QYS2|M0QYS2_HUMAN,tr|M0R0W8|M0R0W8_HUMAN,tr|G3V340|G3V340_HUMAN,tr|M0QXN2|M0QXN2_HUMAN" 11 866.4572 3.15 28641 12130 2 866.457074 434.2359 Striatin-3 OS=Homo sapiens OX=9606 GN=STRN3 PE=1 SV=3 5.75 2796.5 - 1.31E+06 - - - -0.1177 - 1.49 0.302 - 177.5 1 2 0 -0.0001 7 0 0 0 3.85E+07 1.22E+07 - - - 2.5351 0.977 230117_WJC_METTL3_WT_vs_EV_F04.12134.12134.2 0.258 14-May R.LLEEGVLR.Q "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 927.5389 2.23 28642 12134 2 927.537463 464.7767 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 2797 - 657165 - - - -1.5838 - 1.029 0.233 - 53.8 1 2 0 -0.0015 8 0 0 0 1.21E+08 5.42E+07 - - - 0.8477 0.9956 230117_WJC_METTL3_WT_vs_EV_F04.12137.12137.2 0.451 16-Aug R.NVIEAVYSR[166.11].L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1059.5588 1.26 28645 12137 2 1059.559129 530.7867 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 2797.3 - 312709 - - - 0.2831 - 1.494 0.144 - 146.6 1 2 0 0.0003 9 0 0 0 5.96E+07 4.74E+07 - - - 1.2659 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.12140.12140.2 0.0461 16-Jul K.LVPVGYGIK[136.11].K sp|P24534|EF1B_HUMAN 1 952.5837 0.72 28646 12140 2 952.58258 477.2991 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2797.7 - 980228 - - - -1.1799 - 1.296 0.345 - 125.8 1 2 0 -0.0011 9 0 0 0 1.16E+09 1.61E+09 - - - 2.3389 0.9042 230117_WJC_METTL3_WT_vs_EV_F04.12144.12144.2 1.1 12-Jun R.ILLYAC[160.03]R.N "sp|P36954|RPB9_HUMAN,tr|K7EKS1|K7EKS1_HUMAN" 2 907.495 1.09 28648 12144 2 907.491822 454.7548 DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1 8.22 2798.2 - 1.01E+06 - - - -3.4568 - 1.245 0.119 - 129.8 1 2 0 -0.0031 7 0 0 0 7.40E+07 6.77E+07 - - - 0.6133 0.989 230117_WJC_METTL3_WT_vs_EV_F04.12157.12157.2 2.07 12-Aug K.IPVIIER.Y "sp|A6NCE7|MP3B2_HUMAN,sp|Q9GZQ8|MLP3B_HUMAN,sp|Q9H492|MLP3A_HUMAN,tr|H3BTL1|H3BTL1_HUMAN" 4 838.5276 1.34 28654 12157 2 838.527636 420.2711 Microtubule-associated proteins 1A\1B light chain 3 beta 2 OS=Homo sapiens OX=9606 GN=MAP1LC3B2 PE=2 SV=1 6 2799.8 - 1.35E+06 - - - -0.0036 - 1.485 0.052 - 277.3 1 2 0 0 7 0 0 0 4.63E+07 3.45E+07 - - - 0.678 0.9388 230117_WJC_METTL3_WT_vs_EV_F04.12159.12159.2 0.937 14-Jul R.LLEEGVLR[166.11].Q "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 937.5472 2.5 28656 12159 2 937.546602 469.7809 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 2800 - 1.27E+06 - - - -0.64 - 1.266 0.018 - 129.3 2 2 0 -0.0006 8 0 0 0 1.20E+08 4.81E+07 - - - -0.2494 0.9271 230117_WJC_METTL3_WT_vs_EV_F04.12160.12160.2 5.32 12-Jun R.YISGILR.K "sp|P46020|KPB1_HUMAN,sp|P46019|KPB2_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 4 820.4807 1.71 28657 12160 2 820.482798 411.2476 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 8.75 2800.1 - 877143 - - - 2.5704 - 1.11 0.001 - 114.8 1 2 0 0.0021 7 0 0 0 8.17E+07 4.77E+07 - - - -0.6216 0.9916 230117_WJC_METTL3_WT_vs_EV_F04.12171.12171.2 0.249 14-Aug R.VFVSPLAK[136.11].K "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 867.5309 0.75 28658 12171 2 867.528211 434.7727 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 8.72 2801.9 - 5.30E+06 - - - -3.1457 - 1.568 0.302 - 243.4 1 2 0 -0.0027 8 0 0 0 2.83E+08 3.75E+08 - - - 2.6273 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.12187.12187.2 0.33 14-Aug R.VFVSPLAK.K "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 859.5167 0.76 28663 12187 2 859.518671 430.7656 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 8.72 2804.1 - 5.03E+06 - - - 2.2466 - 1.479 0.255 - 219.4 1 2 0 0.0019 8 0 0 0 2.83E+08 3.75E+08 - - - 2.1042 0.9851 230117_WJC_METTL3_WT_vs_EV_F04.12188.12188.2 0.413 12-Jul R.FAAVIMR.L "sp|Q6SJ96|TBPL2_HUMAN,sp|P20226|TBP_HUMAN,tr|Q7Z6S5|Q7Z6S5_HUMAN,tr|A0A1B0GVC6|A0A1B0GVC6_HUMAN,tr|Q32MN6|Q32MN6_HUMAN" 5 806.4473 2.04 28664 12188 2 806.450506 404.2309 TATA box-binding protein-like 2 OS=Homo sapiens OX=9606 GN=TBPL2 PE=2 SV=1 9.75 2804.2 - 1.47E+06 - - - 4.0003 - 1.501 0.104 - 127.8 1 2 0 0.0032 7 0 0 0 8.57E+07 4.21E+07 - - - 1.095 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.12196.12196.3 1.38E-05 Oct-56 K.KVPQVSTPTLVEVSR.N "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1638.9305 999 28667 12196 3 1638.930617 547.3174 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 8.75 2805.2 - 293119 - - - 0.0891 - 2.519 0.436 - 106.4 1 2 0 0.0001 15 0 0 0 7.71E+06 0.00E+00 - - - 5.8116 0.999 230117_WJC_METTL3_WT_vs_EV_F04.12204.12204.2 0.23 16-Sep K.LVPVGYGIK.K sp|P24534|EF1B_HUMAN 1 944.5695 0.72 28669 12204 2 944.569057 473.292 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2806.3 - 1.38E+07 - - - -0.4732 - 1.567 0.378 - 343.5 1 2 0 -0.0004 9 0 0 0 1.15E+09 1.61E+09 - - - 3.1322 0.9939 230117_WJC_METTL3_WT_vs_EV_F04.12221.12221.2 0.0235 12-Jul K.LSIVPVR[166.11].R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 792.5097 0.87 28675 12221 2 792.508996 397.2621 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2808.5 - 2.35E+07 - - - -0.8807 - 1.513 0.162 - 157.8 1 2 0 -0.0007 7 0 0 0 2.50E+09 2.88E+09 - - - 1.5494 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.12231.12231.2 0.0555 14-Aug K.TPVIVTLK[136.11].E "sp|Q9Y4L1|HYOU1_HUMAN,tr|A0A087WWI4|A0A087WWI4_HUMAN,tr|K7EQK2|K7EQK2_HUMAN,tr|A0A087WW13|A0A087WW13_HUMAN,tr|Q9BST8|Q9BST8_HUMAN,tr|J3KTF1|J3KTF1_HUMAN,tr|A0A494C039|A0A494C039_HUMAN,tr|J3QL06|J3QL06_HUMAN,tr|A0A087X214|A0A087X214_HUMAN,tr|A0A087X054|A0A087X054_HUMAN,tr|E9PJ21|E9PJ21_HUMAN,tr|J3QLE9|J3QLE9_HUMAN,tr|J3QQH7|J3QQH7_HUMAN" 13 877.5728 1.37 28679 12231 2 877.573428 439.7937 Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1 8.41 2809.7 - 181936 - - - 0.7099 - 1.504 0.273 - 131.8 1 2 0 0.0006 8 0 0 0 1.22E+07 8.89E+06 - - - 2.2881 0.992 230117_WJC_METTL3_WT_vs_EV_F04.12237.12237.2 0.000255 20-Oct R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 218.09 28681 12237 2 1264.624201 633.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2810.6 - 661219 - - - -4.5318 - 2.078 0.4 - 197.9 1 2 0 -0.0057 11 0 0 0 2.24E+07 1.03E+05 - - - 3.9722 0.9935 230117_WJC_METTL3_WT_vs_EV_F04.12240.12240.2 1.18 14-Jul K.IIGDTFVK.L sp|P49915|GUAA_HUMAN 1 891.5066 2.54 28682 12240 2 891.506398 446.7606 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.84 2811 - 1.87E+06 - - - -0.1918 - 1.376 0.155 - 97.2 1 2 0 -0.0002 8 0 0 0 2.77E+08 1.09E+08 - - - 1.1484 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.12252.12252.2 0.426 12-Aug K.LSIVPVR.R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 782.5014 0.87 28684 12252 2 782.501246 392.258 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2812.9 - 4.97E+07 - - - -0.2275 - 1.588 0.156 - 249.1 1 2 0 -0.0002 7 0 0 0 2.50E+09 2.88E+09 - - - 1.6585 0.9776 230117_WJC_METTL3_WT_vs_EV_F04.12263.12263.2 0.403 16-May K.VLEGMEVVR[166.11].K "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1040.5564 0.11 28687 12263 2 1040.555883 521.2855 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.53 2814.5 - 139722 - - - -0.4834 - 1.17 0.137 - 55.9 2 2 0 -0.0005 9 0 0 0 4.98E+06 4.74E+07 - - - 0.3725 0.9908 230117_WJC_METTL3_WT_vs_EV_F04.12265.12265.2 0.488 12-Jun K.YLYEIAR.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 926.4862 68.41 28688 12265 2 926.486261 464.2504 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6 2814.7 - 6.53E+06 - - - 0.1004 - 1.28 0.128 - 126 1 2 0 0.0001 7 0 0 0 7.34E+08 1.07E+07 - - - 0.7686 0.9895 230117_WJC_METTL3_WT_vs_EV_F04.12304.12304.2 1.84 12-Jul K.GVTLGFR[166.11].Y "sp|P32969|RL9_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 4 758.4314 0.001 28702 12304 2 758.431524 380.223 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 9.75 2820 - 1.95E+06 - - - 0.1055 - 1.312 0.104 - 231.5 1 2 0 0.0001 7 0 0 0 0.00E+00 7.89E+07 - - - 0.6695 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.12311.12311.2 0.00366 12-Aug R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.37 28705 12311 2 852.483746 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2821 - 5.78E+07 - - - 0.1067 - 1.49 0.265 - 204.1 1 2 0 0.0001 7 0 0 0 8.43E+09 6.14E+09 - - - 2.2618 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.12316.12316.2 0.0143 14-Jul R.SLFEQYGK.V "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 970.476 999 28707 12316 2 970.478726 486.2453 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.72 2821.7 - 274611 - - - 2.812 - 1.176 0.327 - 127.4 1 2 0 0.0027 8 0 0 0 1.66E+07 0.00E+00 - - - 1.9443 0.999 230117_WJC_METTL3_WT_vs_EV_F04.12342.12342.2 0.00631 12-Aug R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.45 28722 12342 2 844.470842 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2825 - 3.85E+07 - - - 1.6425 - 1.481 0.287 - 194.5 1 2 0 0.0014 7 0 0 0 1.04E+10 7.17E+09 - - - 2.4047 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.12354.12354.2 0.0342 14-Aug R.LADIVVPR.G sp|Q9NWZ5|UCKL1_HUMAN 1 881.5335 4.37 28728 12354 2 881.534802 441.774 Uridine-cytidine kinase-like 1 OS=Homo sapiens OX=9606 GN=UCKL1 PE=1 SV=2 5.84 2826.6 - 461315 - - - 1.5314 - 1.816 0.267 - 202.7 1 2 0 0.0013 8 0 0 0 1.45E+07 3.31E+06 - - - 2.8121 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.12367.12367.2 0.0628 20-May R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 42.38 28736 12367 2 1201.610501 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2828.2 - 261455 - - - 1.1351 - 1.452 0.312 - 45.8 11 2 0 0.0014 11 0 0 0 1.10E+07 2.60E+05 - - - 1.8887 0.9615 230117_WJC_METTL3_WT_vs_EV_F04.12376.12376.2 0.0189 16-Sep R.PLISVYSEK[136.11].G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1042.579 0.85 28741 12376 2 1042.579681 522.2968 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.42 2829.5 - 339872 - - - 0.6417 - 1.807 0.355 - 339.3 1 1 0 0.0007 9 0 0 0 4.83E+07 5.66E+07 - - - 3.3745 0.9942 230117_WJC_METTL3_WT_vs_EV_F04.12401.12401.2 0.862 12-Jul R.LLSVNIR.V sp|P07814|SYEP_HUMAN 1 813.5072 1.46 28750 12401 2 813.507621 407.7609 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 9.75 2833.1 - 953016 - - - 0.4708 - 1.454 0.104 - 128.9 1 2 0 0.0004 7 0 0 0 1.98E+08 1.36E+08 - - - 0.9951 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.12405.12405.2 0.771 14-Aug K.LIGEYGLR.N "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 919.5127 0.81 28752 12405 2 919.513967 460.7636 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 2833.6 - 2.52E+06 - - - 1.3594 - 1.573 0.147 - 160.7 1 2 0 0.0013 8 0 0 0 2.15E+09 2.66E+09 - - - 1.4925 0.996 230117_WJC_METTL3_WT_vs_EV_F04.12420.12420.2 0.135 12-Jun K.VLPIIQR.W "sp|Q9BYW2|SETD2_HUMAN,tr|H7C3H4|H7C3H4_HUMAN,tr|A0A1W2PPX9|A0A1W2PPX9_HUMAN" 3 837.5436 1.8 28755 12420 2 837.54497 419.7791 Histone-lysine N-methyltransferase SETD2 OS=Homo sapiens OX=9606 GN=SETD2 PE=1 SV=3 9.72 2835.9 - 417755 - - - 1.6083 - 1.212 0.203 - 111.2 1 2 0 0.0013 7 0 0 0 2.75E+07 1.53E+07 - - - 1.1492 0.9664 230117_WJC_METTL3_WT_vs_EV_F04.12424.12424.2 0.00274 16-Oct R.PLISVYSEK.G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1034.5648 0.78 28757 12424 2 1034.567015 518.2897 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.42 2836.4 - 1.02E+06 - - - 2.1294 - 1.677 0.424 - 354.9 1 1 0 0.0022 9 0 0 0 4.38E+07 5.62E+07 - - - 3.6677 0.9342 230117_WJC_METTL3_WT_vs_EV_F04.12429.12429.2 0.364 18-May K.QYGNEVFLAK.L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1167.5924 26.75 28759 12429 2 1167.5935 584.8035 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6 2837.1 - 105563 - - - 0.9216 - 1.095 0.012 - 79.6 2 2 0 0.0011 10 0 0 0 8.32E+06 3.11E+05 - - - -0.7519 1 230117_WJC_METTL3_WT_vs_EV_F04.12452.12452.2 0.000544 18-Nov K.DVNAAIATIK.T "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 8 1014.571 7.17 28767 12452 2 1014.567788 508.2928 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 5.84 2840.2 - 347162 - - - -3.1264 - 2.21 0.483 - 241.1 1 2 0 -0.0032 10 0 0 0 1.95E+07 2.72E+06 - - - 4.8209 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.12464.12464.2 0.713 12-Jul R.IGTFDLK[136.11].Y "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN" 2 800.4524 0.44 28777 12464 2 800.452589 401.2335 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 5.84 2841.6 - 936511 - - - 0.2923 - 1.449 0.163 - 104.5 1 2 0 0.0002 7 0 0 0 2.05E+07 4.62E+07 - - - 1.42 0.9927 230117_WJC_METTL3_WT_vs_EV_F04.12471.12471.2 0.179 14-Jul K.AGLYGLPR[166.11].R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|A0A0U1RRG3|A0A0U1RRG3_HUMAN" 3 855.4842 2.17 28780 12471 2 855.484607 428.7494 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.79 2842.6 - 537102 - - - 0.4664 - 1.301 0.133 - 114 1 2 0 0.0004 8 0 0 0 3.90E+08 1.80E+08 - - - 0.8168 0.9173 230117_WJC_METTL3_WT_vs_EV_F04.12474.12474.2 0.746 12-Jun K.TC[160.03]PLLLR[166.11].V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 881.5032 1.25 28783 12474 2 881.501673 441.7589 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2842.9 - 698972 - - - -1.7652 - 1.258 0.032 - 118.3 1 2 0 -0.0016 7 0 0 0 1.21E+09 9.70E+08 - - - 0.0041 0.9584 230117_WJC_METTL3_WT_vs_EV_F04.12478.12478.2 1.26 12-Jun R.IGTFDLK.Y "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN" 2 792.4382 0.39 28785 12478 2 792.44092 397.2264 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 5.84 2843.4 - 816831 - - - 3.4892 - 1.003 0.143 - 66.4 1 2 0 0.0028 7 0 0 0 2.08E+07 5.28E+07 - - - 0.1058 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.12492.12492.2 0.0226 12-Jun K.TC[160.03]PLLLR.V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 871.495 1.25 28791 12492 2 871.494497 436.7548 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2845.2 - 1.44E+06 - - - -0.5301 - 1.384 0.338 - 166.5 1 2 0 -0.0005 7 0 0 0 1.21E+09 9.70E+08 - - - 2.567 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.12498.12498.2 0.000181 16-Sep R.LYEALTPVH.- "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1041.5495 - 28794 12498 2 1041.551063 521.782 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.24 2846 - 722488 - - - 1.5045 - 1.511 0.413 - 248.2 1 2 0 0.0016 9 0 0 0 - - - - - 3.2851 0.9884 230117_WJC_METTL3_WT_vs_EV_F04.12510.12510.2 0.291 18-Jul R.SINQPVAFVR.R "sp|Q9GZT3|SLIRP_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|H0YJI1|H0YJI1_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1129.6244 1.18 28798 12510 2 1129.627185 565.8195 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 9.47 2847.8 - 127701 - - - 2.4716 - 1.323 0.103 - 124.2 1 2 0 0.0028 10 0 0 0 5.46E+06 4.63E+06 - - - 0.5822 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.12516.12516.3 0.000536 Dec-72 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 32.85 28800 12516 3 2080.028569 694.3481 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2848.6 - 210618 - - - 2.9019 - 1.985 0.425 - 36.6 1 2 0 0.006 19 0 0 0 6.64E+07 2.02E+06 - - - 4.9611 0.982 230117_WJC_METTL3_WT_vs_EV_F04.12518.12518.2 1.86 18-Jun R.TIAQDYGVLK.A "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1106.5972 1.45 28801 12518 2 1106.598955 554.3059 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.5 2848.9 - 136782 - - - 1.6085 - 1.08 0.112 - 81.2 1 2 0 0.0018 10 0 0 0 1.15E+07 7.93E+06 - - - 0.0825 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.12520.12520.4 8.13E-05 15/108 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 3.03 28802 12520 4 2080.025161 521.0129 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2849.1 - 771820 - - - 1.2634 - 1.961 0.442 - 58.8 1 2 0 0.0026 19 0 0 0 3.54E+07 1.17E+07 - - - 3.3003 0.9789 230117_WJC_METTL3_WT_vs_EV_F04.12527.12527.3 0.0148 Aug-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 17.1 28804 12527 3 2088.04405 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2850.1 - 125278 - - - 3.5042 - 1.205 0.231 - 33.1 1 2 0 0.0073 19 0 0 0 3.46E+07 2.02E+06 - - - 1.5715 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.12542.12542.2 0.0071 12-Aug R.WLGEPIK[136.11].A "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 849.484 0.46 28808 12542 2 849.486017 425.7493 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6 2852.3 - 2.38E+06 - - - 2.3862 - 1.567 0.415 - 295.3 1 2 0 0.002 7 0 0 0 1.17E+09 2.54E+09 - - - 3.5288 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.12546.12546.2 0.00169 14-Sep R.LPLQDVYK[136.11].L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 982.5579 5.51 28811 12546 2 982.559391 492.2862 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2852.7 - 2.97E+06 - - - 1.5348 - 1.801 0.15 - 362.5 1 2 0 0.0015 8 0 0 0 2.38E+09 4.32E+08 - - - 1.9228 0.9784 230117_WJC_METTL3_WT_vs_EV_F04.12566.12566.2 1.43 12-Jun R.GDIQTLK[136.11].N sp|Q9HC62|SENP2_HUMAN 1 781.4425 1.1 28818 12566 2 781.441753 391.7285 Sentrin-specific protease 2 OS=Homo sapiens OX=9606 GN=SENP2 PE=1 SV=3 5.84 2855.4 - 6.04E+06 - - - -0.9802 - 1.233 0.123 - 196.1 1 2 0 -0.0008 7 0 0 0 5.44E+08 4.94E+08 - - - 0.6129 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.12568.12568.2 0.251 12-Jul R.WLGEPIK.A "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 841.4698 0.45 28820 12568 2 841.469933 421.7422 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6 2855.6 - 3.53E+06 - - - 0.1699 - 1.276 0.261 - 249.9 1 2 0 0.0001 7 0 0 0 1.14E+09 2.53E+09 - - - 1.741 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.12592.12592.2 0.00105 20-Aug R.TAAENDFVTLK.K sp|P35908|K22E_HUMAN 1 1207.6085 26.41 28828 12592 2 1207.608198 604.8115 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2858.9 - 96477.2 - - - -0.2236 - 1.599 0.453 - 154.5 1 2 0 -0.0003 11 0 0 0 4.76E+06 1.80E+05 - - - 3.6566 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.12594.12594.2 0.00638 12-May R.LVVFDAR[166.11].- sp|P53803|RPAB4_HUMAN 1 828.4733 1.03 28829 12594 2 828.473208 415.2439 "DNA-directed RNA polymerases I, II, and III subunit RPABC4 OS=Homo sapiens OX=9606 GN=POLR2K PE=1 SV=1" 5.84 2859.1 - 4.72E+06 - - - -0.1207 - 1.237 0.353 - 95.7 1 2 0 -0.0001 7 0 0 0 3.19E+08 3.10E+08 - - - 2.3221 0.9159 230117_WJC_METTL3_WT_vs_EV_F04.12595.12595.2 0.0422 14-Jul L.VDHALIAR[166.11].C sp|Q05BV3|EMAL5_HUMAN 1 903.5166 3.88 28830 12595 2 903.517646 452.7656 Echinoderm microtubule-associated protein-like 5 OS=Homo sapiens OX=9606 GN=EML5 PE=2 SV=3 6.71 2859.2 - 547005 - - - 1.1909 - 1.339 0.314 - 182.4 1 1 0 0.0011 8 0 0 0 1.76E+08 4.54E+07 - - - 2.2403 0.9963 230117_WJC_METTL3_WT_vs_EV_F04.12598.12598.2 0.219 16-Jul K.AGLAPLEVR[166.11].V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 934.5475 0.68 28831 12598 2 934.547633 468.281 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.05 2859.6 - 331248 - - - 0.1038 - 1.473 0.195 - 103 2 2 0 0.0001 9 0 0 0 2.33E+07 3.42E+07 - - - 1.4673 0.9903 230117_WJC_METTL3_WT_vs_EV_F04.12604.12604.2 0.373 16-Jun K.AGLAPLEVR.V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 924.5393 0.69 28834 12604 2 924.539466 463.2769 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.05 2860.5 - 328464 - - - 0.2163 - 1.257 0.134 - 91 1 2 0 0.0002 9 0 0 0 2.25E+07 3.25E+07 - - - 0.6924 0.9945 230117_WJC_METTL3_WT_vs_EV_F04.12630.12630.2 0.459 16-Jun K.LVPVGYGIR[166.11].K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 982.5839 0.97 28844 12630 2 982.584929 492.2992 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2863.9 - 4.97E+06 - - - 1.0248 - 1.17 0.193 - 102 1 2 0 0.001 9 0 0 0 7.40E+08 7.62E+08 - - - 0.9204 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.12643.12643.2 0.00234 16-Oct K.IGPLGLSPK.K sp|P30050|RL12_HUMAN 1 880.5382 1.62 28848 12643 2 880.538084 441.2764 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2865.7 - 4.75E+06 - - - -0.1351 - 1.754 0.318 - 278.5 1 2 0 -0.0001 9 0 0 0 1.19E+10 7.34E+09 - - - 3.0153 0.994 230117_WJC_METTL3_WT_vs_EV_F04.12647.12647.2 0.0438 12-Aug R.FAAFIDK.V "sp|Q14533|KRT81_HUMAN,sp|P78386|KRT85_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|U3KPR1|U3KPR1_HUMAN" 6 810.4276 47.09 28850 12647 2 810.427473 406.2211 "Keratin, type II cuticular Hb1 OS=Homo sapiens OX=9606 GN=KRT81 PE=1 SV=3" 5.84 2866.1 - 1.42E+06 - - - -0.1444 - 1.491 0.12 - 155.7 1 2 0 -0.0001 7 0 0 0 8.70E+07 1.85E+06 - - - 1.193 0.9898 230117_WJC_METTL3_WT_vs_EV_F04.12660.12660.2 1.8 12-Jun R.LAILYAK.R "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 790.4953 1.16 28853 12660 2 790.494996 396.2549 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 8.59 2868 - 992042 - - - -0.3542 - 1.481 0.099 - 113.6 2 2 0 -0.0003 7 0 0 0 2.32E+08 2.01E+08 - - - 0.882 0.9917 230117_WJC_METTL3_WT_vs_EV_F04.12663.12663.2 0.343 12-Aug R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 161.73 28854 12663 2 776.380808 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2868.4 - 948101 - - - -1.1528 - 1.414 0.176 - 213.7 1 2 0 -0.0009 7 0 0 0 1.10E+09 6.83E+06 - - - 1.4383 0.9577 230117_WJC_METTL3_WT_vs_EV_F04.12667.12667.2 8.84 16-Jul K.LVPVGYGIR.K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 972.5757 0.97 28856 12667 2 972.574744 487.2951 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2868.8 - 1.37E+07 - - - -0.9336 - 1.206 0.073 - 177.4 1 2 0 -0.0009 9 0 0 0 7.44E+08 7.66E+08 - - - 0.1218 0.962 230117_WJC_METTL3_WT_vs_EV_F04.12673.12673.2 1.92 12-Aug R.TLQVLIK.Q "sp|Q7Z3B4|NUP54_HUMAN,sp|P35219|CAH8_HUMAN" 2 813.5324 2.32 28858 12673 2 813.531641 407.7735 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.41 2869.6 - 1.19E+06 - - - -0.9207 - 1.428 0.003 - 211.8 1 2 0 -0.0007 7 0 0 0 1.71E+08 7.37E+07 - - - 0.1918 0.9972 230117_WJC_METTL3_WT_vs_EV_F04.12678.12678.2 0.386 14-Oct R.LGNSLLLK.Y sp|Q10570|CPSF1_HUMAN 1 856.5382 0.05 28861 12678 2 856.537733 429.2764 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 2870.2 - 1.19E+06 - - - -0.5487 - 1.424 0.264 - 175.1 1 2 0 -0.0005 8 0 0 0 1.12E+08 2.11E+09 - - - 2.0568 0.9453 230117_WJC_METTL3_WT_vs_EV_F04.12713.12713.2 6.71 20-May R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 999 28873 12713 2 1068.65825 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 2875 - 5.94E+06 - - - 3.7 - 1.289 0.093 - 53.4 8 2 0 0.004 11 0 0 0 6.28E+08 0.00E+00 - - - 0.01 0.9446 230117_WJC_METTL3_WT_vs_EV_F04.12719.12719.2 1.97 12-Jul K.FLEPTLR.L "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 874.4913 1.05 28876 12719 2 874.49121 438.2529 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 2875.6 - 1.07E+06 - - - -0.0492 - 1.256 0.006 - 190.4 3 2 0 0 7 0 0 0 3.77E+08 3.58E+08 - - - -0.4056 0.9957 230117_WJC_METTL3_WT_vs_EV_F04.12720.12720.2 0.256 12-Jul K.TAISLLR[166.11].N sp|Q99959|PKP2_HUMAN 1 782.489 1.39 28877 12720 2 782.488996 392.2518 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 9.41 2875.7 - 983810 - - - 0.0473 - 1.308 0.202 - 170.8 1 2 0 0 7 0 0 0 1.18E+08 8.50E+07 - - - 1.3837 0.8892 230117_WJC_METTL3_WT_vs_EV_F04.12724.12724.2 0.206 14-Jul K.TALLGLTK[136.11].T sp|Q9BTZ2|DHRS4_HUMAN 1 823.5259 0.94 28879 12724 2 823.523127 412.7702 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 8.41 2876.2 - 2.15E+06 - - - -3.3114 - 1.435 0.06 - 154.7 2 2 0 -0.0027 8 0 0 0 7.15E+08 7.63E+08 - - - 0.4381 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.12734.12734.2 0.0653 18-Sep R.LIAAATSVLK[136.11].T "sp|P24863|CCNC_HUMAN,tr|E5RFX8|E5RFX8_HUMAN,tr|E5RI39|E5RI39_HUMAN,tr|J3KP90|J3KP90_HUMAN,tr|E5RFK5|E5RFK5_HUMAN,tr|G5E954|G5E954_HUMAN,tr|H0YBQ5|H0YBQ5_HUMAN" 7 993.6314 1.72 28882 12734 2 993.629995 497.823 Cyclin-C OS=Homo sapiens OX=9606 GN=CCNC PE=1 SV=2 8.75 2877.5 - 182593 - - - -1.3959 - 1.715 0.342 - 142.4 1 2 0 -0.0014 10 0 0 0 1.26E+07 7.31E+06 - - - 3.0722 0.998 230117_WJC_METTL3_WT_vs_EV_F04.12739.12739.2 0.0828 12-Jun R.LVNQWIK[136.11].Q "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 907.5371 1.02 28883 12739 2 907.537078 454.7758 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 8.75 2878.2 - 541039 - - - -0.011 - 1.247 0.319 - 79.8 1 2 0 0 7 0 0 0 3.93E+07 3.85E+07 - - - 2.0966 0.9933 230117_WJC_METTL3_WT_vs_EV_F04.12748.12748.2 3.14 14-Aug R.LPVDIAYK.R sp|P15924|DESP_HUMAN 1 917.5222 5.44 28886 12748 2 917.52067 459.7684 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.83 2879.4 - 1.94E+06 - - - -1.6882 - 1.624 0.192 - 245.7 1 2 0 -0.0015 8 0 0 0 3.20E+08 5.88E+07 - - - 1.921 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.12751.12751.4 0.0195 Nov-96 T.LLLIILTDVFIISTVLR.L sp|Q8NGY0|O10X1_HUMAN 1 1941.2278 17.89 28887 12751 4 1941.232417 486.3142 Olfactory receptor 10X1 OS=Homo sapiens OX=9606 GN=OR10X1 PE=3 SV=2 5.84 2879.8 - 2.11E+06 - - - 2.3671 - 1.562 0.422 - 25.9 1 1 0 0.0046 17 0 0 0 8.66E+07 4.84E+06 - - - 3.0527 0.9266 230117_WJC_METTL3_WT_vs_EV_F04.12753.12753.2 0.151 14-Oct D.IADIEALK.E "sp|Q70CQ2|UBP34_HUMAN,sp|O75792|RNH2A_HUMAN,tr|A0A2R8Y606|A0A2R8Y606_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 4 871.5015 1.69 28889 12753 2 871.501225 436.758 Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens OX=9606 GN=USP34 PE=1 SV=2 4.37 2880 - 4.81E+06 - - - -0.2972 - 1.937 0.272 - 253.6 1 1 0 -0.0003 8 0 0 0 3.17E+08 1.88E+08 - - - 3.0439 0.9853 230117_WJC_METTL3_WT_vs_EV_F04.12757.12757.2 0.0257 14-Sep K.FGELVMTK.E "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 923.4786 2.9 28891 12757 2 923.475932 462.7466 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6 2880.5 - 1.19E+06 - - - -2.9324 - 1.276 0.29 - 228.6 1 2 0 -0.0027 8 0 0 0 1.69E+08 5.83E+07 - - - 1.9172 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.12772.12772.2 0.0425 14-Aug K.FGELVMTK[136.11].E "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 931.4928 2.96 28897 12772 2 931.493503 466.7537 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6 2882.4 - 974637 - - - 0.7118 - 1.409 0.26 - 158.5 1 2 0 0.0007 8 0 0 0 1.74E+08 5.88E+07 - - - 1.9953 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.12782.12782.2 0.0112 16-Sep K.IGPLGLSPK[136.11].K sp|P30050|RL12_HUMAN 1 888.5524 1.63 28902 12782 2 888.551278 445.2835 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2883.8 - 5.16E+07 - - - -1.2661 - 1.718 0.276 - 232.2 1 2 0 -0.0011 9 0 0 0 1.19E+10 7.33E+09 - - - 2.6448 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.12799.12799.2 0.113 18-Nov R.ISGLIYEETR[166.11].G sp|P62805|H4_HUMAN 1 1189.6218 0.67 28908 12799 2 1189.622937 595.8182 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2886 - 290514 - - - 0.9364 - 2.237 0.349 - 403.4 1 2 0 0.0011 10 0 0 0 8.72E+06 1.31E+07 - - - 3.8657 0.9864 230117_WJC_METTL3_WT_vs_EV_F04.12803.12803.2 0.466 12-Jun K.LYALDVR.V "sp|O94913|PCF11_HUMAN,tr|E9PKN0|E9PKN0_HUMAN,tr|E9PQF9|E9PQF9_HUMAN,tr|E9PQ01|E9PQ01_HUMAN" 4 848.4756 0.77 28910 12803 2 848.477849 425.2451 Pre-mRNA cleavage complex 2 protein Pcf11 OS=Homo sapiens OX=9606 GN=PCF11 PE=1 SV=3 5.84 2886.4 - 355013 - - - 2.6471 - 1.292 0.092 - 108 1 2 0 0.0022 7 0 0 0 2.00E+07 2.59E+07 - - - 0.5316 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.12813.12813.2 0.0454 20-Oct K.LIADVAPSAIR[166.11].E "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1134.6636 1.36 28913 12813 2 1134.666093 568.3391 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 5.84 2887.8 - 216109 - - - 2.1716 - 1.627 0.248 - 310.4 1 2 0 0.0025 11 0 0 0 2.55E+07 1.87E+07 - - - 2.1887 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.12817.12817.2 0.232 18-Oct R.ISGLIYEETR.G sp|P62805|H4_HUMAN 1 1179.6136 0.67 28915 12817 2 1179.611924 590.8141 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2888.3 - 293710 - - - -1.381 - 2.156 0.359 - 297.9 1 2 0 -0.0016 10 0 0 0 8.72E+06 1.31E+07 - - - 3.8365 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.12835.12835.4 3.82E-06 14/198 R.SDSPVPTAPTSGGPKPSTASAVPELATDPELEKK.L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3360.6937 263.17 28922 12835 4 3360.709644 841.1807 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2890.7 - 272895 - - - 4.7559 - 2.395 0.506 - 68.3 1 2 0 0.016 34 0 0 0 8.85E+06 3.36E+04 - - - 3.8862 0.9937 230117_WJC_METTL3_WT_vs_EV_F04.12840.12840.2 0.0496 14-Jul R.VIAQLEIR.Q "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|E9PLY5|E9PLY5_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A669KBB0|A0A669KBB0_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A5F9ZGX0|A0A5F9ZGX0_HUMAN" 10 940.5706 4.45 28926 12840 2 940.574371 471.2926 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.97 2891.3 - 243512 - - - 4.0454 - 1.4 0.241 - 114.1 1 2 0 0.0038 8 0 0 0 7.80E+06 1.76E+06 - - - 1.8346 0.997 230117_WJC_METTL3_WT_vs_EV_F04.12843.12843.2 0.0718 14-Jul K.QVEELFER[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1058.5272 3.1 28927 12843 2 1058.528784 530.2709 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2891.7 - 234867 - - - 1.5011 - 1.426 0.173 - 214.3 1 2 0 0.0016 8 0 0 0 3.01E+07 9.71E+06 - - - 1.3886 0.9962 230117_WJC_METTL3_WT_vs_EV_F04.12845.12845.2 3.51 16-Oct K.AIPLALEGK[136.11].D "sp|Q9NY93|DDX56_HUMAN,tr|F8WDT8|F8WDT8_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|F8WEI3|F8WEI3_HUMAN" 4 918.563 1.09 28928 12845 2 918.565298 460.2888 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 6.05 2892 - 387872 - - - 2.5366 - 1.577 0.149 - 280.5 1 2 0 0.0023 9 0 0 0 2.02E+07 1.86E+07 - - - 1.4586 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.12847.12847.2 0.0218 18-Sep R.LGPSVVGLAR.Y "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 967.5815 1.41 28929 12847 2 967.583786 484.798 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 9.75 2892.2 - 990918 - - - 2.3988 - 1.762 0.298 - 263.3 1 2 0 0.0023 10 0 0 0 3.89E+07 2.76E+07 - - - 2.8224 0.9782 230117_WJC_METTL3_WT_vs_EV_F04.12857.12857.2 0.433 12-May R.VFLQQLK.G "sp|Q13487|SNPC2_HUMAN,tr|M0QXY9|M0QXY9_HUMAN" 2 874.5276 0.05 28934 12857 2 874.530399 438.2711 snRNA-activating protein complex subunit 2 OS=Homo sapiens OX=9606 GN=SNAPC2 PE=1 SV=1 8.72 2893.6 - 223994 - - - 3.156 - 1.123 0.187 - 54.1 7 2 0 0.0028 7 0 0 0 8.80E+06 1.77E+08 - - - 0.4114 0.9947 230117_WJC_METTL3_WT_vs_EV_F04.12859.12859.2 0.54 12-Sep K.TELLGLK.E sp|Q69YU5|BWNIN_HUMAN 1 772.4695 1.39 28936 12859 2 772.47213 387.242 Protein BRAWNIN OS=Homo sapiens OX=9606 GN=BRAWNIN PE=1 SV=2 5.66 2893.8 - 1.51E+06 - - - 3.4629 - 1.513 0.175 - 336.7 1 2 0 0.0027 7 0 0 0 4.03E+07 2.89E+07 - - - 1.6448 0.9758 230117_WJC_METTL3_WT_vs_EV_F04.12860.12860.3 0.0408 Aug-36 R.LVNHFVEEFK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1260.6503 17.59 28937 12860 3 1260.655938 421.224 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2893.8 - 1.14E+06 - - - 4.4937 - 1.528 0.193 - 97.5 1 2 0 0.0057 10 0 0 0 1.49E+08 8.47E+06 - - - 1.9283 0.8967 230117_WJC_METTL3_WT_vs_EV_F04.12866.12866.2 5.81 14-Aug K.LISGWVSR[166.11].S "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 926.5213 3.81 28941 12866 2 926.525715 464.2679 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 9.75 2894.6 - 354896 - - - 4.7425 - 0.99 0.138 - 131.1 1 2 0 0.0044 8 0 0 0 1.22E+08 3.20E+07 - - - 0.0286 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.12869.12869.2 0.00489 14-Aug K.FQNALLVR.Y "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 959.5553 999 28944 12869 2 959.55802 480.7849 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 9.75 2895 - 196454 - - - 2.8868 - 1.739 0.232 - 197.3 1 2 0 0.0028 8 0 0 0 9.69E+07 0.00E+00 - - - 2.4224 0.9708 230117_WJC_METTL3_WT_vs_EV_F04.12874.12874.2 1.55 14-Jul R.LVEEELLK[136.11].M sp|Q9BW71|HIRP3_HUMAN 1 979.5681 2.98 28947 12874 2 979.567523 490.7913 HIRA-interacting protein 3 OS=Homo sapiens OX=9606 GN=HIRIP3 PE=1 SV=3 4.25 2895.8 - 907718 - - - -0.6023 - 1.139 0.109 - 104.3 1 2 0 -0.0006 8 0 0 0 2.52E+07 8.46E+06 - - - 0.2384 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.12878.12878.2 0.29 16-Sep K.AIPLALEGK.D "sp|Q9NY93|DDX56_HUMAN,tr|F8WDT8|F8WDT8_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|F8WEI3|F8WEI3_HUMAN" 4 910.5488 1.09 28949 12878 2 910.550682 456.2817 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 6.05 2896.2 - 435733 - - - 2.102 - 1.615 0.172 - 257 1 2 0 0.0019 9 0 0 0 2.02E+07 1.86E+07 - - - 1.6975 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.12884.12884.2 0.00608 16-Jul R.LVPLVNGVR.E "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 965.6022 3.15 28953 12884 2 965.604374 483.8084 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 9.75 2897 - 1.69E+06 - - - 2.2504 - 1.656 0.374 - 202.8 1 2 0 0.0022 9 0 0 0 1.15E+08 3.64E+07 - - - 3.262 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.12885.12885.2 0.00731 18-Oct R.LVNHFVEEFK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1260.6503 9.4 28954 12885 2 1260.655615 631.3324 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2897.1 - 836961 - - - 4.2375 - 1.76 0.318 - 197.2 1 2 0 0.0053 10 0 0 0 1.07E+07 1.14E+06 - - - 2.966 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.12886.12886.2 4.82E-05 26-Oct R.LVPGGGATEIELAK.Q sp|P50990|TCPQ_HUMAN 1 1353.7504 23.84 28955 12886 2 1353.754377 677.8825 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 2897.2 - 214622 - - - 2.9518 - 1.879 0.468 - 210.3 1 2 0 0.004 14 0 0 0 2.86E+07 1.20E+06 - - - 4.0792 0.9741 230117_WJC_METTL3_WT_vs_EV_F04.12891.12891.2 1.56 18-May R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 9.4 28958 12891 2 1268.66742 635.3395 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2897.8 - 67782.6 - - - 2.3229 - 1.036 0.114 - 35.8 1 2 0 0.0029 10 0 0 0 1.07E+07 1.14E+06 - - - -0.0192 0.9615 230117_WJC_METTL3_WT_vs_EV_F04.12892.12892.2 1.07 12-Jun R.TILMMGR.Y sp|P13639|EF2_HUMAN 1 820.4299 1.45 28959 12892 2 820.431846 411.2222 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 9.41 2897.9 - 4.23E+06 - - - 2.3536 - 0.931 0.124 - 138 1 2 0 0.0019 7 0 0 0 1.18E+08 8.15E+07 - - - -0.2703 0.9194 230117_WJC_METTL3_WT_vs_EV_F04.12896.12896.2 2.06 12-Jun R.LLEIVER.Q sp|Q12792|TWF1_HUMAN 1 870.5175 1.24 28963 12896 2 870.522376 436.266 Twinfilin-1 OS=Homo sapiens OX=9606 GN=TWF1 PE=1 SV=3 4.53 2898.4 - 267539 - - - 5.638 - 1.445 0.057 - 107.5 1 2 0 0.0049 7 0 0 0 4.69E+07 3.79E+07 - - - 0.6268 0.9945 230117_WJC_METTL3_WT_vs_EV_F04.12903.12903.2 0.102 14-Jul K.LISGWVSR.S "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 916.5131 1.31 28968 12903 2 916.515397 459.2638 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 9.75 2899.1 - 1.40E+06 - - - 2.5597 - 1.275 0.19 - 114.5 1 2 0 0.0023 8 0 0 0 4.05E+07 3.08E+07 - - - 1.1763 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.12904.12904.2 0.00955 16-Jul R.LVPLVNGVR[166.11].E "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 975.6105 3.14 28969 12904 2 975.613101 488.8125 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 9.75 2899.2 - 1.05E+06 - - - 2.6957 - 1.432 0.307 - 121.4 1 2 0 0.0026 9 0 0 0 1.14E+08 3.64E+07 - - - 2.3465 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.12905.12905.2 0.0007 16-Jul K.AFADPEVLR[166.11].R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1026.5374 2.77 28970 12905 2 1026.540572 514.276 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2899.4 - 626765 - - - 3.1241 - 1.398 0.332 - 177.9 1 2 0 0.0032 9 0 0 0 7.07E+07 2.55E+07 - - - 2.4614 0.9475 230117_WJC_METTL3_WT_vs_EV_F04.12906.12906.2 1.03 16-Aug K.IGPLGLSPK.K sp|P30050|RL12_HUMAN 1 880.5382 1.4 28971 12906 2 880.534942 441.2764 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2899.5 - 564207 - - - -3.7034 - 1.47 0.143 - 111.7 1 2 0 -0.0033 9 0 0 0 1.63E+07 1.16E+07 - - - 1.2108 0.9905 230117_WJC_METTL3_WT_vs_EV_F04.12907.12907.2 1.52 14-Jun R.ILLVGEPR.V "sp|Q8IXI2|MIRO1_HUMAN,tr|J3KSR5|J3KSR5_HUMAN" 2 895.5491 1.52 28972 12907 2 895.551444 448.7818 Mitochondrial Rho GTPase 1 OS=Homo sapiens OX=9606 GN=RHOT1 PE=1 SV=2 6 2899.6 - 320200 - - - 2.6152 - 1.3 0.128 - 111.2 1 2 0 0.0023 8 0 0 0 1.72E+07 1.13E+07 - - - 0.777 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.12934.12934.2 0.0636 18-Aug R.LGLMPPPEPK.V sp|O43395|PRPF3_HUMAN 1 1077.5893 4.99 28984 12934 2 1077.592213 539.8019 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6 2903.3 - 154585 - - - 2.7469 - 1.612 0.182 - 163.9 1 2 0 0.003 10 0 0 0 1.04E+07 2.09E+06 - - - 1.7171 0.995 230117_WJC_METTL3_WT_vs_EV_F04.12943.12943.2 1.95 12-Jul R.VAIFIEK.T sp|Q9P258|RCC2_HUMAN 1 818.4902 1.71 28988 12943 2 818.490702 410.2524 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2904.4 - 1.34E+06 - - - 0.6243 - 1.176 0.204 - 160 1 2 0 0.0005 7 0 0 0 9.23E+07 5.41E+07 - - - 1.0613 0.9716 230117_WJC_METTL3_WT_vs_EV_F04.12948.12948.2 1.79 16-Apr K.MLVVGGIDR[166.11].V sp|Q15046|SYK_HUMAN 1 968.5353 1.15 28990 12948 2 968.536278 485.2749 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2905 - 1.88E+06 - - - 1.0542 - 1.213 0.096 - 73 15 2 0 0.001 9 0 0 0 1.68E+08 1.46E+08 - - - -0.217 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.12950.12950.2 0.0759 14-Jul K.GYGFGMVK.L "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RFL1|E5RFL1_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 6 857.4106 1.26 28991 12950 2 857.410675 429.7126 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 8.59 2905.3 - 844289 - - - 0.1341 - 0.94 0.37 - 85.4 1 2 0 0.0001 8 0 0 0 2.68E+07 2.12E+07 - - - 1.5872 0.999 230117_WJC_METTL3_WT_vs_EV_F04.12954.12954.2 0.00818 16-Sep K.MLVVGGIDR.V sp|Q15046|SYK_HUMAN 1 958.527 1.15 28993 12954 2 958.526553 480.2708 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2905.8 - 2.35E+06 - - - -0.4528 - 1.611 0.369 - 355 1 2 0 -0.0004 9 0 0 0 1.69E+08 1.46E+08 - - - 3.1459 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.12958.12958.2 0.258 12-Aug R.VAIFIEK[136.11].T sp|Q9P258|RCC2_HUMAN 1 826.5044 1.72 28995 12958 2 826.503716 414.2595 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2906.2 - 1.41E+06 - - - -0.8167 - 1.965 0.15 - 236 1 2 0 -0.0007 7 0 0 0 9.23E+07 5.37E+07 - - - 2.289 0.9954 230117_WJC_METTL3_WT_vs_EV_F04.12971.12971.2 1.06 12-Jul K.ILEVDLK[136.11].N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 836.5099 0.96 28999 12971 2 836.50929 419.2622 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2908 - 1.16E+06 - - - -0.6934 - 1.642 0.145 - 129.4 1 2 0 -0.0006 7 0 0 0 1.73E+08 1.81E+08 - - - 1.6831 0.9963 230117_WJC_METTL3_WT_vs_EV_F04.12980.12980.2 0.378 12-Jun R.QVAIVFR.T "sp|Q04206|TF65_HUMAN,tr|A0A087X0W8|A0A087X0W8_HUMAN,tr|E9PKH5|E9PKH5_HUMAN,tr|Q2TAM5|Q2TAM5_HUMAN" 4 831.4967 3.69 29000 12980 2 831.496235 416.7556 Transcription factor p65 OS=Homo sapiens OX=9606 GN=RELA PE=1 SV=2 9.75 2909.4 - 1.32E+06 - - - -0.5268 - 1.291 0.264 - 110.8 1 2 0 -0.0004 7 0 0 0 9.36E+07 2.54E+07 - - - 1.8001 0.9762 230117_WJC_METTL3_WT_vs_EV_F04.12987.12987.2 0.126 14-Jul R.SPAQILLR[166.11].W "sp|P14550|AK1A1_HUMAN,sp|Q96JD6|AKCL2_HUMAN,tr|G3V1C1|G3V1C1_HUMAN" 3 906.5526 4.13 29003 12987 2 906.552015 454.2836 Aldo-keto reductase family 1 member A1 OS=Homo sapiens OX=9606 GN=AKR1A1 PE=1 SV=3 9.47 2910.3 - 493687 - - - -0.6685 - 1.087 0.151 - 79.5 1 2 0 -0.0006 8 0 0 0 8.58E+07 2.08E+07 - - - 0.4077 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.13009.13009.3 0.000792 Dec-44 R.LIDLHSPSEIVK.Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1349.7555 2.07 29009 13009 3 1349.753891 450.9258 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2913.4 - 736705 - - - -1.1676 - 1.949 0.349 - 172.7 1 2 0 -0.0016 12 0 0 0 4.13E+07 2.00E+07 - - - 4.2803 0.9089 230117_WJC_METTL3_WT_vs_EV_F04.13019.13019.2 5.32 14-May K.FIINSYPK[136.11].Y "sp|Q96EY7|PTCD3_HUMAN,tr|B8ZZQ4|B8ZZQ4_HUMAN" 2 988.5473 0.9 29014 13019 2 988.547838 495.2809 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 8.59 2914.6 - 332643 - - - 0.526 - 0.914 0.063 - 53.4 2 2 0 0.0005 8 0 0 0 1.33E+07 1.48E+07 - - - -0.8995 0.96 230117_WJC_METTL3_WT_vs_EV_F04.13024.13024.2 1.65 12-May R.FPPYYMR.R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 972.4528 0.7 29018 13024 2 972.45276 487.2337 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 2915.1 - 249055 - - - 0.001 - 1.033 0.106 - 75.5 2 2 0 0 7 0 0 0 1.66E+07 2.39E+07 - - - -0.2077 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.13028.13028.2 0.155 14-Jul K.LEPVVFEK[136.11].V "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 967.547 3.87 29020 13028 2 967.54678 484.7808 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 2915.7 - 350761 - - - -0.2108 - 1.335 0.271 - 123.5 1 2 0 -0.0002 8 0 0 0 1.26E+08 3.25E+07 - - - 1.9139 0.9726 230117_WJC_METTL3_WT_vs_EV_F04.13030.13030.3 4.05 Nov-44 R.LIDLHSPSEIVK[136.11].Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1357.7697 2.07 29022 13030 3 1357.771308 453.5972 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2915.8 - 547990 - - - 1.2086 - 1.585 0.094 - 104.7 1 2 0 0.0016 12 0 0 0 4.12E+07 1.99E+07 - - - 0.8642 0.905 230117_WJC_METTL3_WT_vs_EV_F04.13035.13035.2 3.64 16-Jul K.VGALASLIR.S sp|Q9Y646|CBPQ_HUMAN 1 898.56 524.78 29025 13035 2 898.560753 450.2873 Carboxypeptidase Q OS=Homo sapiens OX=9606 GN=CPQ PE=1 SV=1 9.72 2916.4 - 1.95E+06 - - - 0.8358 - 1.043 0.009 - 88 3 2 0 0.0008 9 0 0 0 1.64E+08 3.13E+05 - - - -0.9841 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.13038.13038.2 0.000765 14-Sep K.VVLVLAGR[166.11].Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 835.5519 0.77 29026 13038 2 835.552907 418.7832 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2916.8 - 4.10E+06 - - - 1.2136 - 1.784 0.333 - 274.3 1 2 0 0.001 8 0 0 0 1.97E+09 2.56E+09 - - - 3.246 0.998 230117_WJC_METTL3_WT_vs_EV_F04.13039.13039.2 0.00976 14-Sep R.QMAAVLLR[166.11].R "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 11 910.5298 1.23 29027 13039 2 910.531644 456.2722 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 2916.9 - 984620 - - - 2.0494 - 1.785 0.142 - 319.8 1 2 0 0.0019 8 0 0 0 6.43E+07 5.22E+07 - - - 1.8367 0.9892 230117_WJC_METTL3_WT_vs_EV_F04.13043.13043.2 0.0356 14-Jul K.LTPVLLAK[136.11].Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 861.5779 1.67 29029 13043 2 861.57718 431.7962 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2917.5 - 5.20E+06 - - - -0.8241 - 1.18 0.205 - 150.3 1 2 0 -0.0007 8 0 0 0 3.26E+08 1.95E+08 - - - 1.0541 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.13044.13044.2 0.00104 14-Aug K.VVLVLAGR.Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 825.5436 0.77 29030 13044 2 825.544557 413.7791 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2917.5 - 3.35E+06 - - - 1.1314 - 1.697 0.394 - 308 1 2 0 0.0009 8 0 0 0 1.97E+09 2.56E+09 - - - 3.5458 0.9446 230117_WJC_METTL3_WT_vs_EV_F04.13047.13047.2 0.68 12-Aug R.LSSFIVK.E sp|P24278|ZBT25_HUMAN 1 792.4745 0.83 29033 13047 2 792.471978 397.2445 Zinc finger and BTB domain-containing protein 25 OS=Homo sapiens OX=9606 GN=ZBTB25 PE=1 SV=2 8.75 2917.7 - 1.61E+06 - - - -3.2342 - 1.661 0.058 - 146.8 2 2 0 -0.0026 7 0 0 0 5.47E+07 6.57E+07 - - - 0.9419 0.9711 230117_WJC_METTL3_WT_vs_EV_F04.13048.13048.2 2.7 12-Jul R.AFGIPVR[166.11].C sp|Q00535|CDK5_HUMAN 1 768.4522 1.25 29034 13048 2 768.452814 385.2334 Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3 9.79 2917.8 - 1.08E+06 - - - 0.8263 - 1.056 0.079 - 144.3 1 2 0 0.0006 7 0 0 0 9.33E+07 7.49E+07 - - - -0.2031 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.13051.13051.2 0.0159 18-Jul R.VNC[160.03]LAPGLIK[136.11].T "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN" 3 1091.6253 0.92 29035 13051 2 1091.629282 546.8199 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 8.19 2918.2 - 340291 - - - 3.6927 - 1.42 0.329 - 147.1 1 2 0 0.004 10 0 0 0 9.46E+06 1.03E+07 - - - 2.4485 0.8695 230117_WJC_METTL3_WT_vs_EV_F04.13071.13071.2 0.00773 12-Jul K.PIIFDC[160.03]R[166.11].S "sp|P35232|PHB_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 4 929.4668 1.83 29045 13071 2 929.469755 465.7407 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 6.22 2921 - 163399 - - - 3.133 - 1.337 0.336 - 144.9 1 1 0 0.0029 7 0 0 0 7.79E+06 4.25E+06 - - - 2.442 0.9703 230117_WJC_METTL3_WT_vs_EV_F04.13073.13073.2 3.52 12-Jun K.LSSLFVK[136.11].C sp|Q92616|GCN1_HUMAN 1 800.4887 1.24 29046 13073 2 800.489689 401.2516 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.75 2921.2 - 1.23E+06 - - - 1.1843 - 1.276 0.068 - 64.2 19 2 0 0.0009 7 0 0 0 8.62E+07 6.97E+07 - - - -0.256 0.9969 230117_WJC_METTL3_WT_vs_EV_F04.13075.13075.2 0.662 14-Jun K.LTPVLLAK.Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 853.5637 1.67 29047 13075 2 853.564799 427.7891 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2921.5 - 9.06E+06 - - - 1.2993 - 1.007 0.311 - 96.3 1 2 0 0.0011 8 0 0 0 3.26E+08 1.95E+08 - - - 1.3587 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.13080.13080.2 0.0331 12-Aug R.FASFIER[166.11].V sp|P07196|NFL_HUMAN 1 878.4526 1.62 29050 13080 2 878.453983 440.2336 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2922 - 1.67E+06 - - - 1.6051 - 1.627 0.238 - 208.6 1 2 0 0.0014 7 0 0 0 1.06E+08 6.53E+07 - - - 2.3407 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.13095.13095.2 2.61 12-Jul R.LISSLLR.T "sp|Q9BQ52|RNZ2_HUMAN,sp|Q8NCN5|PDPR_HUMAN,sp|Q96P20|NLRP3_HUMAN,sp|Q96MN2|NALP4_HUMAN,sp|Q8NGV5|O13D1_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|A0A7I2PMC6|A0A7I2PMC6_HUMAN,tr|E7ES68|E7ES68_HUMAN,tr|A0A2R8YEG7|A0A2R8YEG7_HUMAN,tr|A8MT40|A8MT40_HUMAN,tr|A0A7I2PJH0|A0A7I2PJH0_HUMAN,tr|H3BQG3|H3BQG3_HUMAN,tr|A0A7I2PRX0|A0A7I2PRX0_HUMAN,tr|A0A7I2YME5|A0A7I2YME5_HUMAN,tr|A0A286YF94|A0A286YF94_HUMAN,tr|A0A7I2UNQ2|A0A7I2UNQ2_HUMAN,tr|A0A7I2R3P8|A0A7I2R3P8_HUMAN" 17 800.512 1.45 29056 13095 2 800.513349 401.2633 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 9.75 2924 - 819707 - - - 1.6989 - 1.501 0.097 - 145 1 2 0 0.0014 7 0 0 0 2.99E+07 2.06E+07 - - - 1.0439 0.9815 230117_WJC_METTL3_WT_vs_EV_F04.13097.13097.2 0.671 14-Jun K.LLAEVTLK[136.11].T "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 4 893.5677 2.57 29058 13097 2 893.568009 447.7911 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 6 2924.3 - 421200 - - - 0.3245 - 0.951 0.178 - 66.3 1 2 0 0.0003 8 0 0 0 1.53E+08 5.96E+07 - - - 0.2041 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.13101.13101.2 0.633 14-May R.IFNTFGPR[166.11].M "sp|Q8NBZ7|UXS1_HUMAN,tr|C9JCB7|C9JCB7_HUMAN,tr|C9JFU6|C9JFU6_HUMAN,tr|C9JE50|C9JE50_HUMAN" 4 960.5057 0.8 29060 13101 2 960.506453 481.2601 UDP-glucuronic acid decarboxylase 1 OS=Homo sapiens OX=9606 GN=UXS1 PE=1 SV=1 9.75 2924.8 - 384456 - - - 0.8142 - 1.251 0.257 - 44.7 1 2 0 0.0008 8 0 0 0 3.38E+07 4.26E+07 - - - 1.6144 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.13102.13102.2 0.376 14-Sep K.IADFGLAR.L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 861.4709 2.64 29061 13102 2 861.471337 431.7427 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2924.9 - 1.34E+06 - - - 0.563 - 1.67 0.234 - 200.6 1 2 0 0.0005 8 0 0 0 1.15E+08 4.35E+07 - - - 2.3158 0.9916 230117_WJC_METTL3_WT_vs_EV_F04.13103.13103.2 0.328 12-Jul K.ILMEFNK.M sp|Q9UQE7|SMC3_HUMAN 1 893.4681 1.48 29062 13103 2 893.469063 447.7413 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2925 - 444767 - - - 1.1058 - 1.136 0.157 - 99.9 1 2 0 0.001 7 0 0 0 5.97E+07 4.04E+07 - - - 0.6043 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.13109.13109.2 0.197 14-Jul K.LLAEVTLK.T "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 4 885.5535 2.57 29065 13109 2 885.55467 443.784 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 6 2925.8 - 1.91E+06 - - - 1.2998 - 1.3 0.291 - 121.5 1 2 0 0.0012 8 0 0 0 1.53E+08 5.94E+07 - - - 1.9812 0.9952 230117_WJC_METTL3_WT_vs_EV_F04.13116.13116.2 0.628 12-Aug R.VNLLAVR.D "sp|Q9H4H8|FA83D_HUMAN,tr|A0A087WXK8|A0A087WXK8_HUMAN" 2 783.4967 1.88 29067 13116 2 783.49723 392.7556 Protein FAM83D OS=Homo sapiens OX=9606 GN=FAM83D PE=1 SV=3 9.72 2926.9 - 563264 - - - 0.7109 - 1.573 0.081 - 172.9 1 2 0 0.0006 7 0 0 0 1.82E+07 9.66E+06 - - - 1.0744 0.9925 230117_WJC_METTL3_WT_vs_EV_F04.13125.13125.2 1.15 12-May K.ILMEFNK[136.11].M sp|Q9UQE7|SMC3_HUMAN 1 901.4823 1.42 29071 13125 2 901.483198 451.7484 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2928.1 - 760149 - - - 1.0239 - 1.096 0.184 - 48.1 1 2 0 0.0009 7 0 0 0 6.16E+07 4.35E+07 - - - 0.6902 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.13129.13129.2 0.012 12-Aug K.VVIDAFR.L sp|O00487|PSDE_HUMAN 1 818.465 1.78 29073 13129 2 818.466316 410.2398 26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1 5.81 2928.6 - 4.01E+06 - - - 1.5615 - 1.632 0.165 - 314.5 1 2 0 0.0013 7 0 0 0 3.77E+08 2.12E+08 - - - 1.8113 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.13136.13136.2 0.736 20-Aug K.YGQISEVVVVK[136.11].D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1227.6954 0.9 29078 13136 2 1227.697208 614.855 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2929.4 - 115404 - - - 1.4409 - 1.748 0.24 - 105.8 1 2 0 0.0018 11 0 0 0 4.73E+06 5.25E+06 - - - 2.3239 0.9943 230117_WJC_METTL3_WT_vs_EV_F04.13139.13139.2 0.0594 14-Jun R.LFAAELGR.E "sp|O00255|MEN1_HUMAN,tr|A0A5F9ZHS3|A0A5F9ZHS3_HUMAN,tr|E7EN32|E7EN32_HUMAN,tr|Q9GZQ5|Q9GZQ5_HUMAN,tr|E7ENS2|E7ENS2_HUMAN" 5 875.4865 1.58 29079 13139 2 875.488613 438.7505 Menin OS=Homo sapiens OX=9606 GN=MEN1 PE=1 SV=4 6 2929.8 - 692982 - - - 2.4112 - 1.269 0.198 - 67.8 2 2 0 0.0021 8 0 0 0 3.91E+07 2.47E+07 - - - 1.0868 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.13140.13140.2 7.38E-05 20-Sep K.YGQISEVVVVK.D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1219.6812 0.9 29080 13140 2 1219.686602 610.8479 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2929.9 - 149932 - - - 4.3971 - 1.724 0.459 - 208.8 1 2 0 0.0054 11 0 0 0 4.73E+06 5.25E+06 - - - 3.9029 0.999 230117_WJC_METTL3_WT_vs_EV_F04.13141.13141.2 0.924 14-Aug K.LALDYGIK[136.11].F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 899.5208 1.32 29081 13141 2 899.521597 450.7677 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 2930.1 - 534737 - - - 0.9205 - 1.739 0.234 - 146.8 1 2 0 0.0008 8 0 0 0 2.30E+07 1.75E+07 - - - 2.4378 0.996 230117_WJC_METTL3_WT_vs_EV_F04.13146.13146.2 0.0151 14-Jun K.IGDFGLAR.D "sp|P08922|ROS1_HUMAN,sp|P07333|CSF1R_HUMAN,sp|P51617|IRAK1_HUMAN,sp|Q96PY6|NEK1_HUMAN,sp|P51955|NEK2_HUMAN,sp|Q6P3R8|NEK5_HUMAN,sp|Q16659|MK06_HUMAN,sp|P31152|MK04_HUMAN,tr|E9PIX7|E9PIX7_HUMAN,tr|H7C2I6|H7C2I6_HUMAN,tr|K7EN18|K7EN18_HUMAN,tr|A0A494C168|A0A494C168_HUMAN,tr|F6U4U2|F6U4U2_HUMAN,tr|H7C224|H7C224_HUMAN,tr|K7ELV1|K7ELV1_HUMAN,tr|Q5H8Y1|Q5H8Y1_HUMAN,tr|A0A3B3ITQ6|A0A3B3ITQ6_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 18 847.4552 2.31 29084 13146 2 847.455898 424.7349 Proto-oncogene tyrosine-protein kinase ROS OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3 5.84 2930.8 - 1.36E+06 - - - 0.8213 - 1.715 0.07 - 94.1 1 2 0 0.0007 8 0 0 0 8.02E+07 3.48E+07 - - - 1.1846 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.13151.13151.2 1.69 12-Aug R.LALEELR.S sp|Q99496|RING2_HUMAN 1 842.4862 1.06 29086 13151 2 842.486849 422.2504 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.53 2931.4 - 779733 - - - 0.8083 - 1.654 0.15 - 190.3 1 2 0 0.0007 7 0 0 0 2.70E+08 2.55E+08 - - - 1.7431 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.13162.13162.2 0.604 14-Jun K.VLPITVPK[136.11].S sp|Q9ULW0|TPX2_HUMAN 1 873.5779 2.06 29093 13162 2 873.57913 437.7962 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.72 2932.7 - 438973 - - - 1.4194 - 0.944 0.326 - 59.1 1 2 0 0.0012 8 0 0 0 5.80E+07 2.81E+07 - - - 1.2746 0.9372 230117_WJC_METTL3_WT_vs_EV_F04.13165.13165.2 7.94 14-Jun R.NVVYPLYR.L "sp|Q16540|RM23_HUMAN,tr|A8MYK1|A8MYK1_HUMAN,tr|A8MVT4|A8MVT4_HUMAN,tr|A6NJD9|A6NJD9_HUMAN" 4 1022.5549 32.4 29094 13165 2 1022.556825 512.2847 "39S ribosomal protein L23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL23 PE=1 SV=1" 8.59 2933.1 - 1.11E+06 - - - 1.8669 - 1.089 0.018 - 144.7 2 2 0 0.0019 8 0 0 0 3.28E+07 1.01E+06 - - - -0.704 0.998 230117_WJC_METTL3_WT_vs_EV_F04.13166.13166.2 0.139 14-Jun K.VLPITVPK.S sp|Q9ULW0|TPX2_HUMAN 1 865.5637 2.06 29095 13166 2 865.564527 433.7891 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.72 2933.3 - 1.17E+06 - - - 0.967 - 1.268 0.272 - 86.9 1 2 0 0.0008 8 0 0 0 5.80E+07 2.81E+07 - - - 1.7658 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.13178.13178.2 0.281 16-Aug R.ILVLNGGYR.G "sp|O60870|KIN17_HUMAN,tr|S4R357|S4R357_HUMAN" 2 1003.5815 1.8 29102 13178 2 1003.583025 502.798 DNA\RNA-binding protein KIN17 OS=Homo sapiens OX=9606 GN=KIN PE=1 SV=2 8.75 2934.6 - 748545 - - - 1.5544 - 1.629 0.274 - 194.6 1 2 0 0.0016 9 0 0 0 2.04E+07 1.13E+07 - - - 2.476 0.934 230117_WJC_METTL3_WT_vs_EV_F04.13183.13183.2 0.0114 14-Jul E.ILNPLVSK.A "sp|Q6NUP7|PP4R4_HUMAN,sp|Q9BSC4|NOL10_HUMAN,tr|G3V431|G3V431_HUMAN" 3 882.5539 1.09 29105 13183 2 882.554253 442.2842 Serine\threonine-protein phosphatase 4 regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PPP4R4 PE=1 SV=1 8.75 2935.1 - 1.48E+06 - - - 0.4521 - 1.494 0.333 - 107.7 1 1 0 0.0004 8 0 0 0 9.42E+07 8.66E+07 - - - 2.7112 0.9296 230117_WJC_METTL3_WT_vs_EV_F04.13185.13185.2 0.0238 16-Aug Y.GYIVAAVVK.L sp|Q8NGI9|OR5A2_HUMAN 1 918.5539 168.81 29107 13185 2 918.55408 460.2842 Olfactory receptor 5A2 OS=Homo sapiens OX=9606 GN=OR5A2 PE=2 SV=1 8.59 2935.4 - 643642 - - - 0.246 - 1.493 0.343 - 175.8 1 1 0 0.0002 9 0 0 0 1.76E+07 1.04E+05 - - - 2.7338 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.13198.13198.2 0.0813 14-Jul K.VLTISTLR.L "sp|Q12830|BPTF_HUMAN,tr|F5GXF5|F5GXF5_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN,tr|A0A0A0MR81|A0A0A0MR81_HUMAN" 6 901.5597 0.64 29114 13198 2 901.560368 451.7871 Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3 9.72 2937.1 - 586825 - - - 0.7775 - 1.354 0.308 - 119 1 2 0 0.0007 8 0 0 0 1.08E+07 1.68E+07 - - - 2.2297 0.9883 230117_WJC_METTL3_WT_vs_EV_F04.13199.13199.2 0.0191 16-Jun R.EQVNDLFSR.K "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1106.5356 0.4 29115 13199 2 1106.53405 554.2751 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 2937.3 - 186261 - - - -1.4342 - 1.199 0.235 - 87.6 1 2 0 -0.0016 9 0 0 0 4.55E+06 1.15E+07 - - - 1.3013 0.9247 230117_WJC_METTL3_WT_vs_EV_F04.13219.13219.2 8.03 16-May K.ALQFLEEVK.V sp|P40227|TCPZ_HUMAN 1 1075.5914 47.15 29129 13219 2 1075.592801 538.803 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 2939.7 - 345540 - - - 1.3388 - 1.165 0 - 67.1 6 2 0 0.0014 9 0 0 0 1.80E+07 3.82E+05 - - - -0.8652 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.13220.13220.2 0.251 14-Sep K.VVNPLFEK[136.11].R "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 952.5473 0.86 29130 13220 2 952.548271 477.2809 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.97 2939.8 - 1.72E+06 - - - 1.0005 - 1.766 0.359 - 253.3 1 2 0 0.001 8 0 0 0 1.14E+08 1.32E+08 - - - 3.4075 0.9252 230117_WJC_METTL3_WT_vs_EV_F04.13231.13231.2 0.938 14-Sep S.LAELTGIK[136.11].W "sp|Q71F56|MD13L_HUMAN,tr|A0A3B3IS36|A0A3B3IS36_HUMAN,tr|A0A3B3IRX3|A0A3B3IRX3_HUMAN" 3 851.5208 0.56 29137 13231 2 851.521528 426.7677 Mediator of RNA polymerase II transcription subunit 13-like OS=Homo sapiens OX=9606 GN=MED13L PE=1 SV=1 6 2941.3 - 5.42E+06 - - - 0.8913 - 1.712 0.237 - 262.7 1 1 0 0.0008 8 0 0 0 1.13E+08 2.02E+08 - - - 2.4128 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.13237.13237.2 0.217 14-Jul R.LFVGSIPK.S "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 859.5167 0.9 29140 13237 2 859.517327 430.7656 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.75 2942.1 - 2.11E+06 - - - 0.6829 - 1.297 0.186 - 161.5 1 2 0 0.0006 8 0 0 0 1.44E+09 1.60E+09 - - - 1.1989 0.9864 230117_WJC_METTL3_WT_vs_EV_F04.13249.13249.2 0.373 12-May K.FIPLYSK[136.11].V "sp|Q14694|UBP10_HUMAN,tr|J3KT19|J3KT19_HUMAN,tr|H3BVF1|H3BVF1_HUMAN" 3 874.5044 1.16 29147 13249 2 874.506052 438.2595 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.59 2943.5 - 407408 - - - 1.8994 - 0.959 0.19 - 63.6 1 2 0 0.0017 7 0 0 0 1.10E+08 9.45E+07 - - - 0.3112 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.13256.13256.2 0.000259 14-Sep -.MFAPAVMR[166.11].A sp|Q9P0S2|COX16_HUMAN 1 931.4647 1.48 29150 13256 2 931.463991 466.7396 "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COX16 PE=1 SV=1" 9.5 2944.3 - 422522 - - - -0.7977 - 1.795 0.235 - 268.5 1 2 0 -0.0007 8 0 0 0 4.34E+07 2.94E+07 - - - 2.5408 0.996 230117_WJC_METTL3_WT_vs_EV_F04.13260.13260.2 0.00148 12-Jul K.YGVDLIR.Y sp|Q6UXN9|WDR82_HUMAN 1 834.46 1.38 29153 13260 2 834.460997 418.2373 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 5.84 2944.7 - 471370 - - - 1.2511 - 1.393 0.143 - 171.5 1 2 0 0.001 7 0 0 0 8.66E+07 6.30E+07 - - - 1.1471 0.9819 230117_WJC_METTL3_WT_vs_EV_F04.13261.13261.2 0.264 14-Jun R.IFTNLYGR.H "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 4 982.5236 1.15 29154 13261 2 982.528362 492.2691 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.75 2944.9 - 249487 - - - 4.8304 - 1.352 0.195 - 67 1 2 0 0.0047 8 0 0 0 6.41E+07 5.58E+07 - - - 1.3893 0.9184 230117_WJC_METTL3_WT_vs_EV_F04.13262.13262.2 0.114 16-Aug H.VVVLVATVR[166.11].A "sp|P11586|C1TC_HUMAN,sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 8 964.6309 2.68 29155 13262 2 964.632579 483.3227 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.72 2945 - 167485 - - - 1.7696 - 1.759 0.222 - 184.5 1 1 0 0.0017 9 0 0 0 2.59E+07 9.66E+06 - - - 2.314 0.9969 230117_WJC_METTL3_WT_vs_EV_F04.13266.13266.2 0.832 14-Sep K.LLTLVSTR[166.11].D "sp|Q9NRL2|BAZ1A_HUMAN,tr|A0A087WWN7|A0A087WWN7_HUMAN" 2 911.5679 0.84 29157 13266 2 911.568656 456.7912 Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2 9.75 2945.5 - 549760 - - - 0.7888 - 1.708 0.1 - 173.4 1 2 0 0.0007 8 0 0 0 6.33E+07 7.54E+07 - - - 1.3939 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.13267.13267.2 0.0358 14-Sep -.MFAPAVMR.A sp|Q9P0S2|COX16_HUMAN 1 921.4565 1.48 29158 13267 2 921.457352 461.7355 "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COX16 PE=1 SV=1" 9.5 2945.7 - 690715 - - - 0.9637 - 1.454 0.242 - 272.8 1 2 0 0.0009 8 0 0 0 4.34E+07 2.94E+07 - - - 1.9571 0.9914 230117_WJC_METTL3_WT_vs_EV_F04.13281.13281.2 0.301 22-Jul R.LLLGPAGGGVPK.L sp|Q96SL8|FIZ1_HUMAN 1 1077.6546 1.25 29164 13281 2 1077.655079 539.8346 Flt3-interacting zinc finger protein 1 OS=Homo sapiens OX=9606 GN=FIZ1 PE=1 SV=2 8.75 2947.4 - 176207 - - - 0.4166 - 1.311 0.13 - 79.3 1 2 0 0.0004 12 0 0 0 1.08E+07 8.64E+06 - - - 0.7135 0.9807 230117_WJC_METTL3_WT_vs_EV_F04.13285.13285.2 0.672 12-Jun R.IGLLDPR[166.11].W "sp|Q15459|SF3A1_HUMAN,tr|H7C1L2|H7C1L2_HUMAN" 2 792.4733 1.35 29166 13285 2 792.472972 397.2439 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 5.84 2947.9 - 1.11E+06 - - - -0.424 - 1.191 0.152 - 67.6 4 2 0 -0.0003 7 0 0 0 3.36E+08 2.50E+08 - - - 0.4485 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.13290.13290.2 0.0457 12-Jul K.YGVDLIR[166.11].Y sp|Q6UXN9|WDR82_HUMAN 1 844.4682 1.43 29168 13290 2 844.469428 423.2414 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 5.84 2948.5 - 1.84E+06 - - - 1.4269 - 1.336 0.258 - 202 1 2 0 0.0012 7 0 0 0 9.25E+07 6.46E+07 - - - 1.8641 0.9969 230117_WJC_METTL3_WT_vs_EV_F04.13292.13292.2 0.782 12-Jul K.SVIISIK[136.11].G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 766.5044 1.15 29170 13292 2 766.505351 384.2595 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2948.7 - 1.02E+06 - - - 1.2524 - 1.362 0.181 - 188.7 1 2 0 0.001 7 0 0 0 2.03E+08 1.77E+08 - - - 1.3565 0.9949 230117_WJC_METTL3_WT_vs_EV_F04.13296.13296.2 0.858 12-Jul K.SVIISIK.G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 758.4902 1.15 29171 13296 2 758.49123 380.2524 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2949.2 - 1.31E+06 - - - 1.3698 - 1.229 0.171 - 187.3 1 2 0 0.001 7 0 0 0 2.03E+08 1.77E+08 - - - 0.957 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.13303.13303.2 0.00949 14-Sep R.LLAAFEER.E "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 947.5076 1.26 29175 13303 2 947.50836 474.7611 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.53 2950 - 1.58E+06 - - - 0.7683 - 1.726 0.206 - 237.1 1 2 0 0.0007 8 0 0 0 1.57E+08 1.24E+08 - - - 2.2084 0.9868 230117_WJC_METTL3_WT_vs_EV_F04.13306.13306.2 0.931 14-Sep K.NLILAGVK.G "sp|Q9UBE0|SAE1_HUMAN,tr|B3KNJ4|B3KNJ4_HUMAN,tr|M0QZS6|M0QZS6_HUMAN,tr|A0A590UKC5|A0A590UKC5_HUMAN,tr|M0QX65|M0QX65_HUMAN,tr|A0A590UKA0|A0A590UKA0_HUMAN,tr|A0A590UK93|A0A590UK93_HUMAN" 7 826.5276 3.44 29176 13306 2 826.52668 414.2711 SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1 PE=1 SV=1 8.75 2950.6 - 638485 - - - -1.1603 - 1.518 0.104 - 232.2 1 2 0 -0.001 8 0 0 0 5.52E+07 1.60E+07 - - - 1.0677 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.13312.13312.2 0.0177 14-Jul R.LLAAFEER[166.11].E "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 957.5159 1.25 29179 13312 2 957.516535 479.7652 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.53 2951.3 - 1.96E+06 - - - 0.6611 - 1.558 0.315 - 162.2 1 2 0 0.0006 8 0 0 0 1.57E+08 1.26E+08 - - - 2.7047 0.9958 230117_WJC_METTL3_WT_vs_EV_F04.13315.13315.2 3.01 12-Jun K.TIADIIR.T "sp|P49368|TCPG_HUMAN,sp|Q16878|CDO1_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 800.4756 10.76 29181 13315 2 800.476138 401.2451 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.5 2951.6 - 6.10E+07 - - - 0.6684 - 1.325 0.171 - 130.4 1 2 0 0.0005 7 0 0 0 2.08E+09 1.94E+08 - - - 1.1955 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.13317.13317.2 0.000902 14-Aug K.LVVWAADR.Q "sp|Q96RQ3|MCCA_HUMAN,tr|G5E9X5|G5E9X5_HUMAN,tr|E9PG35|E9PG35_HUMAN,tr|E9PHF7|E9PHF7_HUMAN,tr|F5GYT8|F5GYT8_HUMAN" 5 928.5131 2.04 29182 13317 2 928.51396 465.2638 "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC1 PE=1 SV=3" 5.84 2951.8 - 646590 - - - 0.979 - 1.726 0.422 - 193.5 1 2 0 0.0009 8 0 0 0 3.03E+07 1.49E+07 - - - 3.8037 0.999 230117_WJC_METTL3_WT_vs_EV_F04.13324.13324.2 0.864 18-Dec R.LLAEPVPGIK[136.11].A "sp|P61088|UBE2N_HUMAN,sp|Q5JXB2|UE2NL_HUMAN,tr|F8VZ29|F8VZ29_HUMAN,tr|F8VSD4|F8VSD4_HUMAN,tr|F8VV71|F8VV71_HUMAN" 5 1043.647 1.64 29185 13324 2 1043.648066 522.8308 Ubiquitin-conjugating enzyme E2 N OS=Homo sapiens OX=9606 GN=UBE2N PE=1 SV=1 6 2952.7 - 622701 - - - 0.9908 - 1.864 0.228 - 362 1 2 0 0.001 10 0 0 0 1.22E+08 7.48E+07 - - - 2.4629 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.13326.13326.2 0.086 12-Jul K.IVVLLQR.L "sp|Q06323|PSME1_HUMAN,tr|H0YLU2|H0YLU2_HUMAN" 2 839.5593 1.38 29186 13326 2 839.560045 420.7869 Proteasome activator complex subunit 1 OS=Homo sapiens OX=9606 GN=PSME1 PE=1 SV=1 9.75 2952.9 - 288605 - - - 0.9195 - 1.553 0.341 - 132.4 1 2 0 0.0008 7 0 0 0 3.26E+07 2.37E+07 - - - 2.9541 1 230117_WJC_METTL3_WT_vs_EV_F04.13330.13330.2 1.46E-06 24-Oct R.TTPSYVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1486.694 15.54 29187 13330 2 1486.694914 744.3543 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2953.5 - 405017 - - - 0.6222 - 2.312 0.613 - 294.9 1 2 0 0.0009 13 0 0 0 7.14E+07 4.59E+06 - - - 5.7194 0.9907 230117_WJC_METTL3_WT_vs_EV_F04.13334.13334.2 0.63 14-Aug K.LVALNLDR[166.11].L "sp|Q9Y3D3|RT16_HUMAN,tr|A6ND22|A6ND22_HUMAN" 2 922.5475 1.2 29189 13334 2 922.547212 462.281 "28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1" 5.84 2953.9 - 3.13E+06 - - - -0.3512 - 1.199 0.184 - 126.1 1 2 0 -0.0003 8 0 0 0 8.69E+07 7.23E+07 - - - 0.9473 0.9577 230117_WJC_METTL3_WT_vs_EV_F04.13335.13335.2 0.11 12-May K.ELVVLPR[166.11].E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 834.5203 0.51 29190 13335 2 834.517666 418.2674 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2954 - 909790 - - - -3.1072 - 1.244 0.203 - 88 2 2 0 -0.0026 7 0 0 0 1.91E+08 3.75E+08 - - - 1.0969 0.999 230117_WJC_METTL3_WT_vs_EV_F04.13343.13343.2 0.119 14-Sep R.ILEVLPGR.R sp|Q9UI43|MRM2_HUMAN 1 895.5491 2.34 29192 13343 2 895.550269 448.7818 "rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1" 6 2955.2 - 571788 - - - 1.3031 - 1.717 0.238 - 218.5 1 2 0 0.0012 8 0 0 0 5.24E+07 2.24E+07 - - - 2.4289 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.13344.13344.2 0.000686 16-Sep K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 467.07 29193 13344 2 1059.554832 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2955.3 - 862461 - - - -1.1382 - 1.84 0.376 - 293.2 1 2 0 -0.0012 9 0 0 0 2.53E+07 5.42E+04 - - - 3.5818 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.13345.13345.2 0.131 12-Jul K.YVIYIER[166.11].V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 964.5257 0.81 29194 13345 2 964.52747 483.2701 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 6 2955.4 - 430385 - - - 1.7957 - 1.446 0.368 - 218.1 1 2 0 0.0017 7 0 0 0 9.71E+08 1.20E+09 - - - 2.9271 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.13348.13348.2 0.273 14-Jul K.LVALNLDR.L "sp|Q9Y3D3|RT16_HUMAN,tr|A6ND22|A6ND22_HUMAN" 2 912.5393 1.18 29195 13348 2 912.539189 457.2769 "28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1" 5.84 2955.8 - 1.52E+06 - - - -0.0844 - 1.565 0.269 - 135.7 1 2 0 -0.0001 8 0 0 0 8.54E+07 7.21E+07 - - - 2.3786 0.996 230117_WJC_METTL3_WT_vs_EV_F04.13357.13357.2 0.308 12-Jun K.ELVVLPR.E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 824.512 0.51 29199 13357 2 824.512293 413.2633 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2957.1 - 751365 - - - 0.3687 - 1.305 0.193 - 192.2 1 2 0 0.0003 7 0 0 0 1.92E+08 3.76E+08 - - - 1.3099 0.998 230117_WJC_METTL3_WT_vs_EV_F04.13358.13358.2 0.135 14-Sep R.ILEVLPGR[166.11].R sp|Q9UI43|MRM2_HUMAN 1 905.5574 2.33 29200 13358 2 905.556795 453.786 "rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1" 6 2957.2 - 444478 - - - -0.6372 - 1.759 0.231 - 224.8 1 2 0 -0.0006 8 0 0 0 5.22E+07 2.24E+07 - - - 2.4502 1 230117_WJC_METTL3_WT_vs_EV_F04.13360.13360.2 1.10E-05 24-Oct R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 15.54 29202 13360 2 1496.702849 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2957.4 - 110300 - - - 0.3942 - 2.264 0.53 - 321.8 1 2 0 0.0006 13 0 0 0 7.14E+07 4.59E+06 - - - 5.0526 0.9924 230117_WJC_METTL3_WT_vs_EV_F04.13365.13365.2 6.06 12-Jul K.LLDIVAR.S sp|Q12931|TRAP1_HUMAN 1 798.4963 2.19 29204 13365 2 798.49629 400.2554 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.84 2958.1 - 7.94E+06 - - - -0.0614 - 1.682 0.039 - 164.6 1 2 0 0 7 0 0 0 2.92E+08 1.33E+08 - - - 0.9766 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.13366.13366.2 0.00457 18-Aug R.AFGSLGPGLR.L "sp|Q96JG8|MAGD4_HUMAN,tr|D6RBW3|D6RBW3_HUMAN,tr|A0A804HHZ9|A0A804HHZ9_HUMAN" 3 973.5345 6.39 29205 13366 2 973.536297 487.7745 Melanoma-associated antigen D4 OS=Homo sapiens OX=9606 GN=MAGED4 PE=1 SV=3 9.79 2958.2 - 509727 - - - 1.8304 - 1.477 0.379 - 147.4 1 2 0 0.0018 10 0 0 0 2.00E+07 3.13E+06 - - - 2.9284 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.13375.13375.2 0.0033 12-Aug R.VVFQEFR[166.11].Q sp|P35579|MYH9_HUMAN 1 933.4948 0.89 29209 13375 2 933.49473 467.7547 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2959.3 - 707464 - - - -0.045 - 1.461 0.389 - 275.9 1 2 0 0 7 0 0 0 2.25E+08 2.53E+08 - - - 3.1154 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.13386.13386.2 0.00589 24-Sep R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 15.54 29213 13386 2 1496.707616 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2960.7 - 134446 - - - 3.5792 - 1.988 0.268 - 183 1 2 0 0.0054 13 0 0 0 7.14E+07 4.59E+06 - - - 2.7823 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.13389.13389.2 0.425 14-Sep R.LGALALPR.G "sp|Q6SPF0|SAMD1_HUMAN,tr|E9PIW9|E9PIW9_HUMAN" 2 809.5123 2.14 29214 13389 2 809.5129 405.7634 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.75 2961.1 - 1.67E+06 - - - 0.7128 - 2.147 0.057 - 226.9 3 2 0 0.0006 8 0 0 0 2.03E+08 9.47E+07 - - - 1.5531 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.13394.13394.2 0.0389 14-Jul R.LLSTYLER[166.11].Y "sp|Q12769|NU160_HUMAN,tr|G3V198|G3V198_HUMAN" 2 1003.5578 1.22 29216 13394 2 1003.557996 502.7862 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 6 2961.7 - 581915 - - - 0.2292 - 1.511 0.299 - 130.6 1 2 0 0.0002 8 0 0 0 5.95E+07 4.89E+07 - - - 2.4942 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.13398.13398.2 0.00116 24-Aug K.VIDPATATSVDLR.D sp|P50991|TCPD_HUMAN 1 1356.7249 999 29218 13398 2 1356.725358 679.3697 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 2962.3 - 209695 - - - 0.3413 - 1.601 0.434 - 103.4 1 2 0 0.0005 13 0 0 0 9.48E+06 0.00E+00 - - - 3.4543 0.9941 230117_WJC_METTL3_WT_vs_EV_F04.13407.13407.2 0.197 14-May R.LFVGSIPK[136.11].S "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 867.5309 0.91 29221 13407 2 867.531306 434.7727 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.75 2963.6 - 2.76E+06 - - - 0.4219 - 1.282 0.191 - 47.2 3 2 0 0.0004 8 0 0 0 1.44E+09 1.58E+09 - - - 0.9877 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.13413.13413.2 0.954 12-Jun R.YLLAMER.H "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 894.4633 3.17 29223 13413 2 894.463307 448.2389 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 2964.2 - 518836 - - - -0.019 - 1.297 0.198 - 108.9 1 2 0 0 7 0 0 0 3.52E+07 1.11E+07 - - - 1.3274 0.9769 230117_WJC_METTL3_WT_vs_EV_F04.13417.13417.2 1.07 14-May R.FLAYMEDR[166.11].R "sp|Q9HCK8|CHD8_HUMAN,tr|H0YJG4|H0YJG4_HUMAN" 2 1053.4829 2.56 29226 13417 2 1053.483999 527.7487 Chromodomain-helicase-DNA-binding protein 8 OS=Homo sapiens OX=9606 GN=CHD8 PE=1 SV=5 4.37 2964.7 - 96346.7 - - - 1.0555 - 1.027 0.108 - 65.1 1 2 0 0.0011 8 0 0 0 7.22E+06 2.82E+06 - - - -0.0813 0.9945 230117_WJC_METTL3_WT_vs_EV_F04.13428.13428.2 0.578 14-Aug K.LLIIGPQK.T "sp|P52848|NDST1_HUMAN,tr|E7EVJ3|E7EVJ3_HUMAN" 2 880.5746 0.96 29230 13428 2 880.573829 441.2946 Bifunctional heparan sulfate N-deacetylase\N-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=NDST1 PE=1 SV=1 8.75 2966.2 - 535021 - - - -0.8631 - 1.561 0.169 - 176.4 1 2 0 -0.0008 8 0 0 0 1.89E+07 1.98E+07 - - - 1.6321 0.997 230117_WJC_METTL3_WT_vs_EV_F04.13435.13435.2 0.422 12-Jun R.EALGLLR[166.11].A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 780.4733 1.09 29234 13435 2 780.474048 391.2439 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2967 - 2.58E+06 - - - 0.9481 - 1.399 0.176 - 138.8 1 2 0 0.0007 7 0 0 0 2.04E+08 1.87E+08 - - - 1.4046 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.13436.13436.2 0.0703 12-Jul R.EALGLLR.A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 770.465 1.09 29235 13436 2 770.465809 386.2398 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2967.1 - 1.93E+06 - - - 1.0007 - 1.493 0.167 - 193.6 1 2 0 0.0008 7 0 0 0 2.06E+08 1.88E+08 - - - 1.5441 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.13443.13443.2 0.011 16-Aug R.MPVGSPLLR[166.11].D "sp|Q9NVS2|RT18A_HUMAN,tr|Q5QPA5|Q5QPA5_HUMAN" 2 978.556 1.42 29240 13443 2 978.555435 490.2853 "39S ribosomal protein S18a, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18A PE=1 SV=1" 9.5 2967.9 - 267492 - - - -0.5692 - 1.475 0.288 - 149.1 1 2 0 -0.0006 9 0 0 0 8.40E+07 5.92E+07 - - - 2.2924 0.9609 230117_WJC_METTL3_WT_vs_EV_F04.13450.13450.2 0.0197 12-Oct K.PSVYFIK[136.11].F "sp|Q99865|SPI2A_HUMAN,sp|Q56A73|SPIN4_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 9 860.4887 0.49 29244 13450 2 860.48936 431.2516 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 9.01 2968.7 - 2.24E+06 - - - 0.7194 - 1.788 0.329 - 317.4 1 1 0 0.0006 7 0 0 0 2.43E+08 4.98E+08 - - - 3.312 0.9956 230117_WJC_METTL3_WT_vs_EV_F04.13455.13455.2 3.02 12-Jun K.VLLDQLR[166.11].F "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 865.5261 1.58 29247 13455 2 865.526336 433.7703 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 5.81 2969.3 - 1.59E+06 - - - 0.305 - 1.297 0.189 - 82.7 1 2 0 0.0003 7 0 0 0 2.37E+08 1.50E+08 - - - 1.2609 0.9934 230117_WJC_METTL3_WT_vs_EV_F04.13459.13459.2 0.00862 16-Aug K.LLNYAPLEK.- sp|P62875|RPAB5_HUMAN 1 1059.5964 1.16 29249 13459 2 1059.602715 530.8055 "DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1" 6 2969.8 - 424991 - - - 5.9155 - 1.72 0.35 - 173.6 1 2 0 0.0063 9 0 0 0 1.78E+07 1.53E+07 - - - 3.1931 0.9941 230117_WJC_METTL3_WT_vs_EV_F04.13461.13461.2 3.84 12-Jun K.VLLDQLR.F "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 855.5178 1.22 29251 13461 2 855.518066 428.7662 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 5.81 2969.9 - 2.29E+06 - - - 0.3086 - 1.225 0.182 - 103.1 1 2 0 0.0003 7 0 0 0 2.43E+08 2.00E+08 - - - 1.0282 0.9936 230117_WJC_METTL3_WT_vs_EV_F04.13464.13464.2 0.55 16-Oct K.LPPLPAVER[166.11].V "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1000.5945 1.34 29252 13464 2 1000.595763 501.3045 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6 2970.4 - 1.19E+06 - - - 1.2762 - 1.742 0.038 - 328.6 2 2 0 0.0013 9 0 0 0 1.65E+08 1.23E+08 - - - 0.7925 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.13467.13467.2 0.0246 12-Jul R.VVFQEFR.Q sp|P35579|MYH9_HUMAN 1 923.4865 0.89 29254 13467 2 923.488161 462.7505 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2970.7 - 2.69E+06 - - - 1.7965 - 1.461 0.365 - 244.7 1 2 0 0.0017 7 0 0 0 2.25E+08 2.53E+08 - - - 2.9376 0.9743 230117_WJC_METTL3_WT_vs_EV_F04.13471.13471.2 3.77 12-Jun K.QLLYLEK.Y "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 3 905.5222 0.95 29257 13471 2 905.523188 453.7684 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 6 2971.2 - 1.14E+06 - - - 1.0701 - 1.058 0.085 - 108.2 1 2 0 0.001 7 0 0 0 6.34E+07 6.70E+07 - - - -0.1529 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.13473.13473.2 0.00132 20-Aug K.NFYYAAVPSAR[166.11].N sp|Q10471|GALT2_HUMAN 1 1267.6225 0.85 29259 13473 2 1267.625009 634.8185 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.59 2971.4 - 90522.4 - - - 1.9856 - 1.551 0.369 - 194.8 1 2 0 0.0025 11 0 0 0 1.06E+06 1.25E+06 - - - 2.953 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.13477.13477.2 0.00825 16-Oct R.IVDPEIALK.L "sp|P33240|CSTF2_HUMAN,tr|A0A0A0MT56|A0A0A0MT56_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 996.5855 3.28 29261 13477 2 996.587267 499.3001 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.37 2971.9 - 1.15E+06 - - - 1.7249 - 2.047 0.432 - 209.1 1 2 0 0.0017 9 0 0 0 9.39E+08 2.87E+08 - - - 4.3037 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.13479.13479.2 0.00222 20-Aug K.QAGVFEPTIVK.V "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1187.655 32.35 29263 13479 2 1187.657086 594.8348 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2972.2 - 251018 - - - 1.7362 - 1.613 0.39 - 211.9 1 2 0 0.0021 11 0 0 0 1.57E+07 4.86E+05 - - - 3.2143 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.13486.13486.2 0.0516 16-Aug K.VVLLTEVDK.L sp|P40938|RFC3_HUMAN 1 1014.5961 1.72 29265 13486 2 1014.598492 508.3053 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 4.37 2973.1 - 495177 - - - 2.3458 - 1.586 0.286 - 160.7 1 2 0 0.0024 9 0 0 0 4.26E+07 2.48E+07 - - - 2.487 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.13491.13491.2 0.0913 16-Aug K.VVLLTEVDK[136.11].L sp|P40938|RFC3_HUMAN 1 1022.6103 1.72 29267 13491 2 1022.609999 512.3124 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 4.37 2973.8 - 423698 - - - -0.3061 - 1.492 0.211 - 201 1 2 0 -0.0003 9 0 0 0 4.26E+07 2.47E+07 - - - 1.7569 0.978 230117_WJC_METTL3_WT_vs_EV_F04.13500.13500.2 0.965 12-Oct K.PSVYFIK.F "sp|Q99865|SPI2A_HUMAN,sp|Q56A73|SPIN4_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 9 852.4745 0.49 29272 13500 2 852.475211 427.2445 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 9.01 2974.7 - 7.43E+06 - - - 0.7859 - 2.185 0.397 - 348 1 1 0 0.0007 7 0 0 0 2.43E+08 4.98E+08 - - - 4.4496 0.997 230117_WJC_METTL3_WT_vs_EV_F04.13501.13501.2 0.251 14-Oct K.IADFGLAR[166.11].L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 871.4791 1.95 29273 13501 2 871.479807 436.7468 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2974.8 - 1.46E+06 - - - 0.786 - 1.599 0.132 - 327.2 1 2 0 0.0007 8 0 0 0 8.60E+08 4.42E+08 - - - 1.4314 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.13526.13526.2 0.0776 14-Sep K.LLQLVEDR.G "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 984.5604 0.51 29287 13526 2 984.560377 493.2875 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 2977.8 - 834895 - - - -0.0183 - 1.656 0.212 - 253.2 1 2 0 0 8 0 0 0 1.41E+08 2.74E+08 - - - 2.1281 0.9856 230117_WJC_METTL3_WT_vs_EV_F04.13527.13527.2 0.218 12-Jun R.FILIQNR.A "sp|P53680|AP2S1_HUMAN,tr|M0R0N4|M0R0N4_HUMAN,tr|X6R390|X6R390_HUMAN,tr|M0QYZ2|M0QYZ2_HUMAN" 4 902.5338 1.05 29288 13527 2 902.532178 452.2742 AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2 9.75 2977.9 - 1.00E+06 - - - -1.7828 - 1.308 0.192 - 113.9 1 2 0 -0.0016 7 0 0 0 3.63E+07 3.47E+07 - - - 1.3094 0.9933 230117_WJC_METTL3_WT_vs_EV_F04.13533.13533.2 0.283 14-Oct K.IADFGLAR.L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 861.4709 1.94 29292 13533 2 861.467879 431.7427 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2978.6 - 1.19E+07 - - - -3.4511 - 1.916 0.29 - 305.2 1 2 0 -0.003 8 0 0 0 8.54E+08 4.41E+08 - - - 3.1431 0.9557 230117_WJC_METTL3_WT_vs_EV_F04.13537.13537.2 0.00126 16-Oct K.PLYVALAQR[166.11].K "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PIK9|A0A6I8PIK9_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 25 1039.6054 1.12 29294 13537 2 1039.604636 520.81 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.18 2979 - 586949 - - - -0.7205 - 2.005 0.471 - 424.9 1 1 0 -0.0008 9 0 0 0 3.76E+08 3.36E+08 - - - 4.5321 0.9893 230117_WJC_METTL3_WT_vs_EV_F04.13549.13549.2 0.0155 12-Jun R.YFEPLVK.K "sp|Q7L590|MCM10_HUMAN,tr|Q5T670|Q5T670_HUMAN" 2 894.4851 3.88 29301 13549 2 894.484161 448.2498 Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2 6 2980.6 - 625329 - - - -1.0554 - 1.186 0.216 - 90.7 1 2 0 -0.0009 7 0 0 0 9.84E+07 2.53E+07 - - - 1.1766 0.9914 230117_WJC_METTL3_WT_vs_EV_F04.13573.13573.2 2.47 14-Nov R.LAVEALVR[166.11].T "sp|Q92839|HYAS1_HUMAN,tr|M0QXH4|M0QXH4_HUMAN,tr|G3V1S7|G3V1S7_HUMAN,tr|M0R2V0|M0R2V0_HUMAN" 4 879.5417 7.22 29310 13573 2 879.54095 440.7781 Hyaluronan synthase 1 OS=Homo sapiens OX=9606 GN=HAS1 PE=1 SV=2 6 2983.9 - 3.04E+06 - - - -0.8777 - 1.729 0.077 - 539.7 1 2 0 -0.0008 8 0 0 0 5.23E+09 7.24E+08 - - - 1.2608 0.9965 230117_WJC_METTL3_WT_vs_EV_F04.13576.13576.2 0.0349 14-Jul R.LLAFAEAR.A "sp|Q8WUY8|NAT14_HUMAN,sp|Q99519|NEUR1_HUMAN,tr|M0R1E3|M0R1E3_HUMAN,tr|E9PIF4|E9PIF4_HUMAN" 4 889.5022 2.2 29311 13576 2 889.500765 445.7584 Probable N-acetyltransferase 14 OS=Homo sapiens OX=9606 GN=NAT14 PE=1 SV=1 6 2984.2 - 1.54E+06 - - - -1.5593 - 1.399 0.332 - 133.3 1 2 0 -0.0014 8 0 0 0 6.42E+07 2.92E+07 - - - 2.5053 0.9299 230117_WJC_METTL3_WT_vs_EV_F04.13588.13588.2 0.826 14-Jul K.LLQPLVPR[166.11].Y sp|Q8N8A6|DDX51_HUMAN 1 944.6047 1.04 29319 13588 2 944.603489 473.3096 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2985.5 - 439278 - - - -1.2365 - 1.194 0.044 - 105.6 1 2 0 -0.0012 8 0 0 0 9.81E+07 9.43E+07 - - - -0.0996 0.9781 230117_WJC_METTL3_WT_vs_EV_F04.13591.13591.2 0.513 12-Jul K.ILEVDLK[136.11].N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 836.5099 0.85 29320 13591 2 836.50898 419.2622 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2985.9 - 1.14E+06 - - - -1.0639 - 1.389 0.076 - 127.6 1 2 0 -0.0009 7 0 0 0 2.55E+08 2.99E+08 - - - 0.6432 0.9892 230117_WJC_METTL3_WT_vs_EV_F04.13600.13600.2 0.11 14-Sep K.LLQPLVPR.Y sp|Q8N8A6|DDX51_HUMAN 1 934.5964 1.04 29324 13600 2 934.594057 468.3055 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2987 - 1.30E+06 - - - -2.4931 - 1.535 0.219 - 260.1 1 2 0 -0.0023 8 0 0 0 9.81E+07 9.43E+07 - - - 1.9502 0.9961 230117_WJC_METTL3_WT_vs_EV_F04.13606.13606.2 0.0992 14-Aug K.IINDLLAR.S "sp|P51530|DNA2_HUMAN,tr|F8VR31|F8VR31_HUMAN,tr|H0Y455|H0Y455_HUMAN" 3 926.5549 2.86 29327 13606 2 926.552865 464.2847 DNA replication ATP-dependent helicase\nuclease DNA2 OS=Homo sapiens OX=9606 GN=DNA2 PE=1 SV=3 5.84 2987.7 - 291760 - - - -2.2136 - 1.515 0.346 - 139.9 1 2 0 -0.0021 8 0 0 0 2.35E+07 8.22E+06 - - - 2.8488 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.13608.13608.2 0.168 12-Jul R.YLDELMK.L "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 910.447 1.78 29328 13608 2 910.446399 456.2308 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 2987.9 - 861125 - - - -0.6656 - 1.311 0.316 - 128 1 2 0 -0.0006 7 0 0 0 4.10E+07 2.30E+07 - - - 2.2328 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.13609.13609.2 0.0201 14-Jul K.ILDVMYSR[166.11].L sp|P78527|PRKDC_HUMAN 1 1005.5193 1 29329 13609 2 1005.518055 503.7669 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2988 - 524933 - - - -1.2103 - 1.369 0.374 - 103.9 1 2 0 -0.0012 8 0 0 0 6.73E+07 6.71E+07 - - - 2.7502 0.9845 230117_WJC_METTL3_WT_vs_EV_F04.13615.13615.2 0.231 14-Jul R.ALVIVMGK.E "tr|G5E9Q6|G5E9Q6_HUMAN,tr|C9J0J7|C9J0J7_HUMAN" 2 829.5095 2.58 29332 13615 2 829.507953 415.762 Profilin OS=Homo sapiens OX=9606 GN=PFN2 PE=1 SV=1 8.8 2988.7 - 3.29E+06 - - - -1.9204 - 1.302 0.201 - 123.5 1 2 0 -0.0016 8 0 0 0 9.61E+07 3.73E+07 - - - 1.321 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.13623.13623.2 0.0028 12-Sep K.C[160.03]FLTAMR.E "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN" 3 897.4201 1.66 29337 13623 2 897.419423 449.7173 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 8.25 2989.5 - 1.01E+06 - - - -0.731 - 1.594 0.381 - 407.1 1 2 0 -0.0007 7 0 0 0 3.58E+07 2.15E+07 - - - 3.3322 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.13639.13639.2 0.00329 18-Aug K.QQLLIGAYAK.A sp|Q99832|TCPH_HUMAN 1 1103.6339 13.46 29344 13639 2 1103.633309 552.8242 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.59 2991.7 - 291262 - - - -0.531 - 1.459 0.383 - 142 1 2 0 -0.0006 10 0 0 0 7.58E+06 5.63E+05 - - - 2.9241 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.13640.13640.2 0.00146 12-Aug K.C[160.03]FLTAMR[166.11].E "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN" 3 907.4283 1.66 29345 13640 2 907.427203 454.7215 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 8.25 2991.8 - 434119 - - - -1.2629 - 1.563 0.398 - 241.3 1 2 0 -0.0011 7 0 0 0 3.58E+07 2.15E+07 - - - 3.3954 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.13655.13655.2 4.39 14-Aug K.LAVEAVLR.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 869.5335 7.22 29350 13655 2 869.533899 435.774 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 2993.9 - 8.48E+07 - - - 0.5141 - 1.724 0.239 - 273.5 1 2 0 0.0004 8 0 0 0 5.26E+09 7.28E+08 - - - 2.4487 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.13659.13659.2 0.0641 16-Aug K.VLEEALLSR[166.11].E "sp|Q92667|AKAP1_HUMAN,tr|I3L0W0|I3L0W0_HUMAN" 2 1038.5949 1.16 29354 13659 2 1038.595389 520.3047 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 4.53 2994.3 - 477518 - - - 0.4901 - 1.684 0.216 - 131.5 1 2 0 0.0005 9 0 0 0 2.46E+08 2.12E+08 - - - 2.144 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.13663.13663.2 0.952 12-Jul K.EAVLLLK[136.11].K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 792.52 0.74 29356 13663 2 792.520461 397.2673 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 2994.8 - 1.60E+06 - - - 0.53 - 1.457 0.224 - 163.3 1 2 0 0.0004 7 0 0 0 6.71E+08 9.04E+08 - - - 1.8879 0.9927 230117_WJC_METTL3_WT_vs_EV_F04.13665.13665.2 0.106 14-Aug R.DLAPIGIR.V "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 853.5022 0.98 29358 13665 2 853.503112 427.7584 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 5.84 2995 - 1.24E+06 - - - 1.1248 - 1.41 0.085 - 241.2 1 2 0 0.001 8 0 0 0 2.32E+08 2.36E+08 - - - 0.7048 0.9936 230117_WJC_METTL3_WT_vs_EV_F04.13667.13667.2 1.04 12-Jun K.VLEILGK[136.11].K "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 10 778.5044 2.54 29360 13667 2 778.504987 390.2595 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.97 2995.2 - 337985 - - - 0.7656 - 1.405 0.14 - 80 5 2 0 0.0006 7 0 0 0 5.20E+07 2.05E+07 - - - 0.84 0.9884 230117_WJC_METTL3_WT_vs_EV_F04.13675.13675.2 1.22 12-Jun K.EAVLLLK.K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 784.5058 0.74 29364 13675 2 784.505387 393.2602 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 2996.3 - 2.32E+06 - - - -0.5787 - 1.344 0.123 - 167.4 1 2 0 -0.0005 7 0 0 0 6.70E+08 9.04E+08 - - - 0.8861 0.9899 230117_WJC_METTL3_WT_vs_EV_F04.13681.13681.2 2.5 12-Jul R.LLQIIER[166.11].Y sp|P78527|PRKDC_HUMAN 1 893.5574 1.2 29368 13681 2 893.558182 447.786 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2997 - 2.49E+06 - - - 0.9065 - 1.396 0.072 - 141.1 2 2 0 0.0008 7 0 0 0 2.84E+08 2.36E+08 - - - 0.4951 0.9936 230117_WJC_METTL3_WT_vs_EV_F04.13718.13718.2 0.399 14-Jun K.AAFAPFGR[166.11].L "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 5 845.4423 1.38 29385 13718 2 845.444407 423.7284 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 9.79 3001.9 - 360076 - - - 2.4413 - 1.136 0.214 - 79 1 2 0 0.0021 8 0 0 0 2.32E+07 1.68E+07 - - - 1.0055 0.9896 230117_WJC_METTL3_WT_vs_EV_F04.13740.13740.2 0.488 16-Jul K.SLTMVALAK.L "sp|P83111|LACTB_HUMAN,tr|H0YNN5|H0YNN5_HUMAN" 2 932.5365 2.39 29398 13740 2 932.538363 467.2755 "Serine beta-lactamase-like protein LACTB, mitochondrial OS=Homo sapiens OX=9606 GN=LACTB PE=1 SV=2" 8.47 3004.6 - 129645 - - - 2.0096 - 1.192 0.132 - 86.4 1 2 0 0.0019 9 0 0 0 9.05E+06 3.79E+06 - - - 0.5235 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.13751.13751.2 0.0441 14-Aug K.AAFAPFGR.L "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 5 835.4341 1.42 29404 13751 2 835.435096 418.7243 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 9.79 3005.9 - 638004 - - - 1.2245 - 1.586 0.282 - 245 1 2 0 0.001 8 0 0 0 2.24E+07 1.58E+07 - - - 2.5145 0.9786 230117_WJC_METTL3_WT_vs_EV_F04.13758.13758.2 1.26 18-Jul R.AVLGPVPLTR.T sp|Q96S90|LYSM1_HUMAN 1 1021.6284 3.53 29409 13758 2 1021.631717 511.8215 LysM and putative peptidoglycan-binding domain-containing protein 1 OS=Homo sapiens OX=9606 GN=LYSMD1 PE=1 SV=1 9.79 3006.8 - 164057 - - - 3.2321 - 1.459 0.067 - 100.3 2 2 0 0.0033 10 0 0 0 3.98E+06 1.13E+06 - - - 0.4548 0.8539 230117_WJC_METTL3_WT_vs_EV_F04.13763.13763.2 0.123 14-Jul F.GPVLNYLR[166.11].H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 940.537 0.82 29412 13763 2 940.537767 471.2758 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3007.4 - 502388 - - - 0.8463 - 1.587 0.172 - 149.9 1 1 0 0.0008 8 0 0 0 4.03E+07 4.88E+07 - - - 1.704 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.13768.13768.2 0.0528 22-Oct R.TVIIEQSWGSPK[136.11].V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1351.7227 2.29 29415 13768 2 1351.728742 676.8686 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 3008 - 138157 - - - 4.458 - 2.09 0.455 - 291.2 1 2 0 0.006 12 0 0 0 1.54E+07 6.73E+06 - - - 4.3393 0.999 230117_WJC_METTL3_WT_vs_EV_F04.13769.13769.2 0.0318 14-Aug R.FLGC[160.03]VDIK.D "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 950.4895 1.63 29416 13769 2 950.491958 476.252 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 5.83 3008 - 1.37E+06 - - - 2.545 - 1.379 0.368 - 175.8 1 2 0 0.0024 8 0 0 0 4.35E+07 2.67E+07 - - - 2.7275 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.13770.13770.2 0.0862 22-Aug R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 2.29 29417 13770 2 1343.712611 672.8615 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 3008.2 - 307358 - - - 3.0475 - 1.807 0.257 - 75.6 1 2 0 0.0041 12 0 0 0 1.54E+07 6.73E+06 - - - 2.4947 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.13772.13772.2 0.117 14-Sep R.NLLSVAYK.N "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB2|A2IDB2_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|K7EIT4|K7EIT4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 22 906.5175 1.53 29418 13772 2 906.519236 454.266 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 8.59 3008.4 - 7.02E+06 - - - 1.9503 - 1.616 0.308 - 326.6 1 2 0 0.0018 8 0 0 0 5.19E+08 3.40E+08 - - - 2.7629 0.9618 230117_WJC_METTL3_WT_vs_EV_F04.13779.13779.2 0.00688 18-Oct T.LGSATALMIR[166.11].E "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 1041.588 1 29422 13779 2 1041.590441 521.8013 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3009.2 - 125512 - - - 2.3234 - 2.055 0.343 - 221.7 1 1 0 0.0024 10 0 0 0 1.99E+07 2.00E+07 - - - 3.5841 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.13795.13795.2 0.399 12-Jul K.FTAILYR.T "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 882.4963 0.68 29431 13795 2 882.498185 442.2554 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.75 3011.3 - 3.59E+06 - - - 2.0918 - 1.588 0.155 - 225 1 2 0 0.0018 7 0 0 0 1.59E+08 2.34E+08 - - - 1.6506 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.13801.13801.3 0.00336 Nov-36 R.MVNHFIAEFK.R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1234.6169 0.8 29434 13801 3 1234.619452 412.5462 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 3012 - 1.19E+06 - - - 2.0954 - 1.817 0.361 - 132.2 1 2 0 0.0026 10 0 0 0 4.05E+07 5.08E+07 - - - 4.3081 0.9931 230117_WJC_METTL3_WT_vs_EV_F04.13802.13802.2 0.0968 18-Jul K.ILAEESYLYK.H sp|Q9NVX0|HAUS2_HUMAN 1 1227.6387 3.17 29435 13802 2 1227.643751 614.8266 HAUS augmin-like complex subunit 2 OS=Homo sapiens OX=9606 GN=HAUS2 PE=1 SV=1 4.53 3012.1 - 139336 - - - 4.1103 - 1.414 0.242 - 122.4 1 2 0 0.005 10 0 0 0 4.77E+06 1.51E+06 - - - 1.7938 0.917 230117_WJC_METTL3_WT_vs_EV_F04.13805.13805.2 5.16 12-Apr K.MSILGVR.S "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|E9PM98|E9PM98_HUMAN,tr|A0A494BZW0|A0A494BZW0_HUMAN" 8 774.4422 1.6 29436 13805 2 774.443887 388.2284 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 9.5 3012.5 - 792432 - - - 2.1848 - 1.222 0.016 - 59.1 24 2 0 0.0017 7 0 0 0 4.09E+07 2.56E+07 - - - -0.8226 0.9726 230117_WJC_METTL3_WT_vs_EV_F04.13806.13806.2 0.931 14-Jun K.VLVPQIPR[166.11].L sp|Q10469|MGAT2_HUMAN 1 930.589 1.1 29437 13806 2 930.589582 466.3018 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 3012.6 - 502766 - - - 0.6179 - 1.028 0.101 - 86.9 1 2 0 0.0006 8 0 0 0 9.19E+07 8.36E+07 - - - -0.1299 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.13810.13810.2 0.0234 12-Aug K.LVYILNR.D sp|Q15393|SF3B3_HUMAN 1 889.5385 1.36 29439 13810 2 889.540604 445.7765 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 3013.1 - 8.16E+06 - - - 2.3226 - 1.382 0.242 - 263.4 1 2 0 0.0021 7 0 0 0 3.15E+08 2.33E+08 - - - 1.8529 0.9934 230117_WJC_METTL3_WT_vs_EV_F04.13812.13812.2 0.0381 12-Aug R.ISPLQFR[166.11].- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 869.4999 3.03 29441 13812 2 869.501052 435.7572 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 3013.2 - 2.87E+06 - - - 1.3732 - 1.486 0.064 - 246.3 1 2 0 0.0012 7 0 0 0 3.68E+08 1.21E+08 - - - 0.7684 0.9937 230117_WJC_METTL3_WT_vs_EV_F04.13816.13816.2 0.624 18-Jul R.YPVNSVNILK.A "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1145.6445 19.41 29443 13816 2 1145.645205 573.8295 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.59 3013.7 - 278427 - - - 0.6512 - 1.427 0.143 - 80.8 3 2 0 0.0007 10 0 0 0 1.64E+07 8.43E+05 - - - 0.8763 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.13822.13822.2 0.0879 14-Aug K.VLVPQIPR.L sp|Q10469|MGAT2_HUMAN 1 920.5807 1.1 29447 13822 2 920.582288 461.2976 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 3014.4 - 702950 - - - 1.6848 - 1.491 0.302 - 242.9 1 2 0 0.0016 8 0 0 0 9.27E+07 8.45E+07 - - - 2.4758 0.999 230117_WJC_METTL3_WT_vs_EV_F04.13831.13831.2 0.000212 16-Sep K.YDGIILPGK[136.11].- "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 982.5579 1.38 29452 13831 2 982.556897 492.2862 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.83 3015.6 - 828964 - - - -1.0035 - 1.693 0.415 - 254.1 1 2 0 -0.001 9 0 0 0 3.16E+07 2.29E+07 - - - 3.6291 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.13832.13832.2 0.00555 14-Aug K.ITAFIVER.D "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 947.544 0.57 29453 13832 2 947.545558 474.7793 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 6 3015.7 - 1.34E+06 - - - 1.6263 - 1.757 0.313 - 164.8 1 2 0 0.0015 8 0 0 0 5.33E+07 9.40E+07 - - - 3.0521 0.9915 230117_WJC_METTL3_WT_vs_EV_F04.13835.13835.2 0.0397 12-Jul R.ISPLQFR.- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 859.4916 3.03 29454 13835 2 859.492873 430.7531 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 3016.1 - 8.34E+06 - - - 1.4951 - 1.392 0.068 - 237.2 1 2 0 0.0013 7 0 0 0 3.69E+08 1.22E+08 - - - 0.5908 0.9936 230117_WJC_METTL3_WT_vs_EV_F04.13840.13840.2 3.8 12-Jun R.LVQLLVK.A sp|P14923|PLAK_HUMAN 1 811.5531 17.53 29457 13840 2 811.554414 406.7838 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 8.75 3016.7 - 1.21E+06 - - - 1.5883 - 1.464 0.075 - 66.4 1 2 0 0.0013 7 0 0 0 2.18E+08 1.25E+07 - - - 0.8023 0.9944 230117_WJC_METTL3_WT_vs_EV_F04.13850.13850.2 0.464 14-Jun R.VIFTSPIK[136.11].A sp|P42285|MTREX_HUMAN 1 911.5572 1.14 29464 13850 2 911.55848 456.7859 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 8.72 3017.8 - 1.29E+06 - - - 1.4547 - 1.132 0.2 - 108.1 1 2 0 0.0013 8 0 0 0 1.09E+08 9.54E+07 - - - 0.8917 0.9945 230117_WJC_METTL3_WT_vs_EV_F04.13865.13865.2 0.206 12-Jul R.YYFEGIK.Q "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN" 3 918.4487 2.26 29473 13865 2 918.450844 460.2316 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 6 3019.7 - 1.33E+06 - - - 2.3126 - 1.159 0.213 - 135.5 1 2 0 0.0021 7 0 0 0 4.80E+07 2.12E+07 - - - 1.0811 0.9956 230117_WJC_METTL3_WT_vs_EV_F04.13879.13879.2 0.0431 16-Jul R.VPPEFLVQR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1093.616 1.51 29483 13879 2 1093.617789 547.8153 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3021.3 - 255876 - - - 1.6816 - 1.25 0.191 - 145.9 1 2 0 0.0018 9 0 0 0 9.02E+07 5.98E+07 - - - 1.0967 0.9951 230117_WJC_METTL3_WT_vs_EV_F04.13885.13885.2 0.602 12-Jun R.TIPVVFK.D "sp|P25685|DNJB1_HUMAN,tr|A0A7I2V3K7|A0A7I2V3K7_HUMAN" 2 802.4953 0.7 29487 13885 2 802.497005 402.2549 DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4 8.41 3022.1 - 1.32E+06 - - - 2.1545 - 1.207 0.199 - 116.7 1 2 0 0.0017 7 0 0 0 4.83E+07 6.90E+07 - - - 1.1064 0.8539 230117_WJC_METTL3_WT_vs_EV_F04.13888.13888.2 0.0557 14-Jul K.IDVAFVDR.A sp|Q15645|PCH2_HUMAN 1 933.492 1.82 29490 13888 2 933.485447 467.7533 Pachytene checkpoint protein 2 homolog OS=Homo sapiens OX=9606 GN=TRIP13 PE=1 SV=2 4.21 3022.4 - 786253 - - - -7.0006 - 1.378 0.266 - 93.7 1 2 0 -0.0065 8 0 0 0 2.45E+07 1.35E+07 - - - 1.9706 0.996 230117_WJC_METTL3_WT_vs_EV_F04.13894.13894.2 0.448 14-Aug R.LPWAVAGR.S sp|Q8NBX0|SCPDL_HUMAN 1 868.4919 2.08 29493 13894 2 868.492811 435.2532 Saccharopine dehydrogenase-like oxidoreductase OS=Homo sapiens OX=9606 GN=SCCPDH PE=1 SV=1 9.75 3023.1 - 882568 - - - 1.0236 - 1.578 0.101 - 198.2 1 2 0 0.0009 8 0 0 0 6.83E+07 3.28E+07 - - - 1.1625 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.13898.13898.2 0.000877 12-Jul K.LFEMAYK.K "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 900.4415 4.48 29495 13898 2 900.442717 451.228 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6 3023.7 - 5.03E+06 - - - 1.3227 - 1.477 0.406 - 164 1 2 0 0.0012 7 0 0 0 1.19E+09 2.65E+08 - - - 3.2751 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.13909.13909.2 0.0207 12-Jul K.LFEMAYK[136.11].K "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 908.4557 4.48 29501 13909 2 908.456734 455.2351 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6 3025 - 3.37E+06 - - - 1.1096 - 1.559 0.315 - 161.5 1 2 0 0.001 7 0 0 0 1.19E+09 2.64E+08 - - - 2.7743 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.13912.13912.2 0.00305 18-Jul R.LTPYEVDELR.R "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1233.6241 1.42 29504 13912 2 1233.623706 617.8193 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.14 3025.3 - 188151 - - - -0.334 - 1.548 0.348 - 124.2 1 2 0 -0.0004 10 0 0 0 6.00E+06 4.23E+06 - - - 2.8309 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.13917.13917.2 0.0019 18-Oct K.VLQSALAAIR[166.11].H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1050.6425 1.04 29506 13917 2 1050.643604 526.3285 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 3025.9 - 996446 - - - 1.0517 - 2.23 0.178 - 276.9 1 2 0 0.0011 10 0 0 0 2.78E+08 2.66E+08 - - - 2.594 1 230117_WJC_METTL3_WT_vs_EV_F04.13923.13923.2 0.00337 18-Nov K.VLQSALAAIR.H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1040.6342 1.04 29510 13923 2 1040.635152 521.3244 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 3026.7 - 971390 - - - 0.887 - 2.41 0.419 - 374 1 2 0 0.0009 10 0 0 0 2.78E+08 2.66E+08 - - - 4.5907 0.99 230117_WJC_METTL3_WT_vs_EV_F04.13926.13926.2 0.814 20-Jun R.LLADPTGAFGK.E sp|P30044|PRDX5_HUMAN 1 1088.5866 3.31 29513 13926 2 1088.588691 545.3006 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.84 3026.9 - 157287 - - - 1.9117 - 1.125 0.158 - 57.5 1 2 0 0.0021 11 0 0 0 2.61E+07 7.89E+06 - - - 0.526 0.9925 230117_WJC_METTL3_WT_vs_EV_F04.13931.13931.2 0.166 14-Oct K.IAADILIK.E "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 855.543 0.95 29515 13931 2 855.540867 428.7788 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.84 3027.5 - 541604 - - - -2.4394 - 1.65 0.234 - 191.5 1 2 0 -0.0021 8 0 0 0 1.63E+07 1.71E+07 - - - 2.279 0.9951 230117_WJC_METTL3_WT_vs_EV_F04.13938.13938.2 0.192 12-Jul R.NLVSYLK.Q "sp|Q96T37|RBM15_HUMAN,sp|Q8NDT2|RB15B_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 5 835.4804 0.6 29519 13938 2 835.481651 418.7475 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 8.59 3028.4 - 625774 - - - 1.5524 - 1.35 0.136 - 139.9 1 2 0 0.0013 7 0 0 0 2.58E+07 4.27E+07 - - - 0.996 0.999 230117_WJC_METTL3_WT_vs_EV_F04.13939.13939.2 0.0174 16-Jul R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 999 29520 13939 2 1030.592559 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 3028.5 - 3.55E+07 - - - 1.4865 - 1.711 0.24 - 125 1 2 0 0.0015 9 0 0 0 5.18E+09 0.00E+00 - - - 2.367 1 230117_WJC_METTL3_WT_vs_EV_F04.13940.13940.2 0.000136 28-Nov K.NQVALNPQNTVFDAK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1657.8424 999 29521 13940 2 1657.84706 829.9285 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3028.6 - 139983 - - - 2.8205 - 2.266 0.49 - 214.6 1 2 0 0.0047 15 0 0 0 6.00E+06 0.00E+00 - - - 4.6698 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.13950.13950.2 0.0977 14-Jun R.YPEEFALR.D "sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN" 4 1023.5025 0.43 29525 13950 2 1023.504194 512.7585 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.53 3029.8 - 500644 - - - 1.6102 - 1.198 0.246 - 118.8 1 2 0 0.0016 8 0 0 0 1.69E+07 3.90E+07 - - - 1.4023 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.13954.13954.2 0.0445 18-Nov K.LAEALYIADR.K "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1133.6081 1.01 29528 13954 2 1133.608293 567.8113 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 3030.3 - 329438 - - - 0.1932 - 2.46 0.339 - 451.8 1 2 0 0.0002 10 0 0 0 6.76E+07 6.70E+07 - - - 4.0574 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.13955.13955.2 0.217 18-Nov K.LAEALYIADR[166.11].K "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1143.6163 1.67 29529 13955 2 1143.616663 572.8154 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 3030.4 - 309503 - - - 0.2789 - 2.138 0.185 - 390.8 1 2 0 0.0003 10 0 0 0 6.35E+07 3.80E+07 - - - 2.5283 0.987 230117_WJC_METTL3_WT_vs_EV_F04.13969.13969.2 0.107 20-Jun K.VMPTLAPVVAK.L sp|Q8IWI9|MGAP_HUMAN 1 1124.6628 1.43 29536 13969 2 1124.662786 563.3387 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 8.72 3032.4 - 168272 - - - 0.0302 - 1.108 0.166 - 63.7 1 2 0 0 11 0 0 0 5.67E+06 3.98E+06 - - - 0.5445 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.13979.13979.2 9.59E-05 16-Aug K.FTPGAVMLR.V "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 990.5321 1.36 29542 13979 2 990.533293 496.2733 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.75 3033.6 - 540199 - - - 1.2327 - 1.534 0.459 - 202.4 1 2 0 0.0012 9 0 0 0 4.86E+07 3.58E+07 - - - 3.6687 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.13989.13989.2 0.000827 14-Jul R.VLVLVPTR[166.11].E "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 905.5938 0.88 29546 13989 2 905.594586 453.8042 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 9.72 3034.9 - 1.98E+06 - - - 0.9143 - 1.692 0.224 - 217.3 1 2 0 0.0008 8 0 0 0 7.27E+07 8.23E+07 - - - 2.2813 0.9154 230117_WJC_METTL3_WT_vs_EV_F04.13993.13993.2 0.0395 12-Jul K.SAEFLLH.M "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 815.4178 - 29547 13993 2 815.418136 408.7162 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 5.22 3035.5 - 2.43E+06 - - - 0.4685 - 1.502 0.281 - 236.6 1 1 0 0.0004 7 0 0 0 - - - - - 2.4053 0.946 230117_WJC_METTL3_WT_vs_EV_F04.13995.13995.2 0.473 12-Jun R.IIAFLLK[136.11].L "sp|Q5VW38|GP107_HUMAN,tr|G5E994|G5E994_HUMAN" 2 824.5615 0.79 29549 13995 2 824.562614 413.288 Protein GPR107 OS=Homo sapiens OX=9606 GN=GPR107 PE=1 SV=1 8.75 3035.7 - 465687 - - - 1.3365 - 1.143 0.003 - 94.6 2 2 0 0.0011 7 0 0 0 7.29E+06 9.26E+06 - - - -0.6482 0.991 230117_WJC_METTL3_WT_vs_EV_F04.13998.13998.2 0.186 12-Aug R.LFVLTTK.N sp|Q96RS6|NUDC1_HUMAN 1 820.5058 2.58 29550 13998 2 820.509089 411.2602 NudC domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NUDCD1 PE=1 SV=2 8.75 3036.1 - 393179 - - - 3.9585 - 1.578 0.135 - 180.2 1 2 0 0.0032 7 0 0 0 3.68E+07 1.43E+07 - - - 1.4825 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.13999.13999.2 0.00443 18-Jul K.NLQEAEEWYK.S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1308.5986 1.91 29551 13999 2 1308.603923 655.3066 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3036.3 - 125276 - - - 4.0433 - 1.39 0.4 - 122.9 1 2 0 0.0053 10 0 0 0 2.05E+07 1.07E+07 - - - 2.9129 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.14004.14004.2 0.000728 14-Jul R.VLVLVPTR.E "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 895.5855 0.88 29554 14004 2 895.586122 448.8 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 9.72 3036.9 - 1.64E+06 - - - 0.7079 - 1.62 0.368 - 202.4 1 2 0 0.0006 8 0 0 0 7.27E+07 8.23E+07 - - - 3.2138 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.14007.14007.2 0.0942 14-Aug R.LPLATIVK.D sp|O94776|MTA2_HUMAN 1 853.5637 1.52 29557 14007 2 853.565076 427.7891 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 3037.2 - 657367 - - - 1.6238 - 1.611 0.322 - 140.7 1 2 0 0.0014 8 0 0 0 2.32E+08 1.53E+08 - - - 2.857 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.14008.14008.2 0.154 18-Oct K.NLQEAEEWYK[136.11].S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1316.6128 1.9 29558 14008 2 1316.612716 659.3137 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3037.4 - 115392 - - - -0.0881 - 1.539 0.311 - 217.4 1 2 0 -0.0001 10 0 0 0 2.03E+07 1.07E+07 - - - 2.5414 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.14017.14017.2 0.122 14-Jul R.EAVLSLYR.A sp|L0R8F8|MIDUO_HUMAN 1 949.5233 0.95 29560 14017 2 949.524369 475.7689 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 6.1 3038.7 - 1.40E+06 - - - 1.1448 - 1.415 0.239 - 150.5 1 2 0 0.0011 8 0 0 0 5.25E+07 5.54E+07 - - - 1.8528 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.14021.14021.2 0.00413 14-Aug R.VWAEYALK[136.11].R sp|Q6P2Q9|PRP8_HUMAN 1 986.5317 1.27 29562 14021 2 986.533144 494.2731 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3039.1 - 1.44E+06 - - - 1.4962 - 1.608 0.372 - 253.1 1 2 0 0.0015 8 0 0 0 2.42E+08 1.91E+08 - - - 3.2207 0.9911 230117_WJC_METTL3_WT_vs_EV_F04.14025.14025.2 0.015 16-Aug K.FTPGAVMLR[166.11].V "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1000.5403 1.98 29565 14025 2 1000.541325 501.2774 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.75 3039.6 - 785692 - - - 0.9825 - 1.32 0.099 - 213.9 1 2 0 0.001 9 0 0 0 4.51E+07 2.28E+07 - - - 0.5751 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.14036.14036.2 0.00356 14-Jul R.VWAEYALK.R sp|Q6P2Q9|PRP8_HUMAN 1 978.5175 1.21 29570 14036 2 978.518079 490.266 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3040.9 - 2.60E+06 - - - 0.6244 - 1.556 0.455 - 201 1 2 0 0.0006 8 0 0 0 2.45E+08 2.02E+08 - - - 3.7348 0.9846 230117_WJC_METTL3_WT_vs_EV_F04.14038.14038.2 0.397 14-Jun K.LYLADPMK.A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 949.4943 1.58 29572 14038 2 949.493866 475.7544 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 3041.1 - 2.00E+06 - - - -0.4466 - 1.03 0.202 - 95.1 1 2 0 -0.0004 8 0 0 0 2.51E+08 1.59E+08 - - - 0.622 1 230117_WJC_METTL3_WT_vs_EV_F04.14046.14046.2 7.57E-06 13/18 R.VPLVAPEDLR[166.11].D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1117.6371 0.47 29576 14046 2 1117.639024 559.8258 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3042.1 - 560855 - - - 1.7403 - 2.53 0.455 - 827.9 1 2 0 0.0019 10 0 0 0 3.52E+08 7.52E+08 - - - 4.992 0.999 230117_WJC_METTL3_WT_vs_EV_F04.14052.14052.2 0.000103 18-Nov R.VPLVAPEDLR.D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1107.6288 0.5 29579 14052 2 1107.627439 554.8217 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3042.9 - 460088 - - - -1.2369 - 2.413 0.346 - 536.2 1 2 0 -0.0014 10 0 0 0 7.06E+08 1.41E+09 - - - 4.0549 0.9858 230117_WJC_METTL3_WT_vs_EV_F04.14054.14054.2 0.0417 16-Jul K.GVVTAEMFR.H "sp|Q8N3U4|STAG2_HUMAN,tr|B1AMT1|B1AMT1_HUMAN,tr|B1AMT4|B1AMT4_HUMAN,tr|B1AMT3|B1AMT3_HUMAN,tr|B1AMT2|B1AMT2_HUMAN" 5 1008.5063 2.42 29581 14054 2 1008.511117 505.2604 Cohesin subunit SA-2 OS=Homo sapiens OX=9606 GN=STAG2 PE=1 SV=3 6 3043.2 - 683982 - - - 4.825 - 1.279 0.249 - 114.5 1 2 0 0.0049 9 0 0 0 1.04E+07 4.29E+06 - - - 1.5905 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.14057.14057.2 0.00105 14-Sep K.LYLADPMK[136.11].A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 957.5085 1.58 29582 14057 2 957.507821 479.7615 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 3043.6 - 2.92E+06 - - - -0.6987 - 1.853 0.443 - 261.9 1 2 0 -0.0007 8 0 0 0 2.51E+08 1.59E+08 - - - 4.173 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.14061.14061.2 0.384 14-Aug R.ALVLAQIR.K "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHA0|A0A6Q8PHA0_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF69|A0A6Q8PF69_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PGR0|A0A6Q8PGR0_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN,tr|A0A6Q8PFN8|A0A6Q8PFN8_HUMAN" 16 882.5651 1.72 29584 14061 2 882.566109 442.2898 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 9.79 3044 - 696588 - - - 1.158 - 1.507 0.205 - 201.3 1 2 0 0.001 8 0 0 0 1.73E+07 1.01E+07 - - - 1.7917 0.9835 230117_WJC_METTL3_WT_vs_EV_F04.14074.14074.2 0.0623 14-Jun K.FVDGEWYR.A sp|Q7KZF4|SND1_HUMAN 1 1070.4821 1.08 29589 14074 2 1070.481402 536.2483 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.37 3045.8 - 500482 - - - -0.6941 - 0.961 0.238 - 98.5 1 2 0 -0.0007 8 0 0 0 8.75E+06 8.09E+06 - - - 0.6787 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.14078.14078.2 1.08 12-Sep K.IISIIVK.N "sp|Q9Y4A5|TRRAP_HUMAN,sp|Q6PEY0|CXB7_HUMAN,sp|Q96QE4|LR37B_HUMAN,tr|J3QSU1|J3QSU1_HUMAN,tr|J3KTP0|J3KTP0_HUMAN,tr|A0A0A0MRM5|A0A0A0MRM5_HUMAN,tr|J3QLI7|J3QLI7_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 9 784.5422 1.34 29592 14078 2 784.543475 393.2784 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3046.3 - 607267 - - - 1.592 - 1.979 0.037 - 200.5 1 2 0 0.0012 7 0 0 0 2.38E+07 1.78E+07 - - - 1.4767 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.14081.14081.2 0.0046 12-Aug R.FTDILVR.H sp|O43143|DHX15_HUMAN 1 862.4913 1.07 29593 14081 2 862.491231 432.2529 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 3046.7 - 5.41E+06 - - - -0.0255 - 1.576 0.331 - 229.6 1 2 0 0 7 0 0 0 4.40E+08 4.11E+08 - - - 2.9271 1 230117_WJC_METTL3_WT_vs_EV_F04.14092.14092.2 2.09E-05 20-Nov K.YFVEAGAMAVR.R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1212.5961 10.52 29599 14092 2 1212.598588 607.3053 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3048.1 - 668110 - - - 2.0279 - 2.143 0.526 - 425.4 1 2 0 0.0025 11 0 0 0 6.77E+08 6.43E+07 - - - 4.9872 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.14099.14099.3 0.00387 Oct-68 R.VAPEEHPVLLTEAPLNPK.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1953.0571 16.63 29603 14099 3 1953.059643 652.0263 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 3049.1 - 190398 - - - 1.2877 - 1.829 0.296 - 76.1 1 2 0 0.0025 18 0 0 0 2.75E+06 1.66E+05 - - - 3.3429 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.14106.14106.2 0.00163 20-Sep K.YFVEAGAMAVR[166.11].R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1222.6044 10.41 29608 14106 2 1222.605582 612.3095 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3050 - 129941 - - - 0.9676 - 1.921 0.465 - 278.2 1 2 0 0.0012 11 0 0 0 6.69E+08 6.43E+07 - - - 4.2412 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.14122.14122.2 0.00979 26-Jun K.IFVGGLSPDTPEEK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1487.7508 1.54 29618 14122 2 1487.752021 744.8827 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3052 - 158614 - - - 0.8375 - 1.487 0.441 - 49.5 2 2 0 0.0012 14 0 0 0 7.24E+06 4.70E+06 - - - 3.159 0.9944 230117_WJC_METTL3_WT_vs_EV_F04.14130.14130.2 0.35 12-Sep K.IAWALSR.K sp|Q04760|LGUL_HUMAN 1 815.4654 1.14 29624 14130 2 815.465585 408.74 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 9.75 3052.8 - 1.27E+06 - - - 0.26 - 1.621 0.07 - 260.7 1 2 0 0.0002 7 0 0 0 1.05E+08 9.22E+07 - - - 1.0885 0.9894 230117_WJC_METTL3_WT_vs_EV_F04.14131.14131.2 0.253 12-Jun R.SLEVILR[166.11].A sp|Q14566|MCM6_HUMAN 1 838.5152 1.24 29625 14131 2 838.514993 420.2649 DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1 5.72 3052.9 - 654562 - - - -0.2147 - 1.167 0.171 - 104.3 1 2 0 -0.0002 7 0 0 0 4.10E+07 3.30E+07 - - - 0.7933 0.999 230117_WJC_METTL3_WT_vs_EV_F04.14134.14134.2 1.09 16-Nov K.LADMGIAIR[166.11].V sp|Q9Y3I0|RTCB_HUMAN 1 968.5353 1.33 29626 14134 2 968.536057 485.2749 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.84 3053.3 - 1.74E+06 - - - 0.826 - 1.864 0.218 - 448.5 1 2 0 0.0008 9 0 0 0 2.24E+08 1.68E+08 - - - 2.4525 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.14139.14139.2 0.012 12-Sep R.VFDMLNR[166.11].R "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 12 903.4512 1.61 29629 14139 2 903.452327 452.7329 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3053.9 - 1.39E+06 - - - 1.2552 - 1.78 0.377 - 308.5 1 2 0 0.0011 7 0 0 0 5.17E+07 3.21E+07 - - - 3.6522 0.9251 230117_WJC_METTL3_WT_vs_EV_F04.14140.14140.2 6 14-Jun K.LLGPVLVK.Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 837.5688 3.83 29630 14140 2 837.568869 419.7917 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 3054 - 1.34E+06 - - - 0.1122 - 1.159 0.017 - 64.3 4 2 0 0.0001 8 0 0 0 9.72E+08 2.53E+08 - - - -0.6574 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.14141.14141.2 0.000552 18-Oct R.VPYVIISAAK.G "sp|P28340|DPOD1_HUMAN,tr|M0QXQ2|M0QXQ2_HUMAN,tr|M0QXE6|M0QXE6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 5 1059.6328 1.01 29631 14141 2 1059.63283 530.8237 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.56 3054.1 - 363303 - - - -0.0019 - 2.042 0.424 - 317.3 1 2 0 0 10 0 0 0 7.06E+06 6.96E+06 - - - 4.1655 0.986 230117_WJC_METTL3_WT_vs_EV_F04.14154.14154.2 0.0183 16-Jul R.VPPEFLVQR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1093.616 1.52 29640 14154 2 1093.621844 547.8153 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3055.8 - 259147 - - - 5.3895 - 1.263 0.303 - 146.6 1 2 0 0.0059 9 0 0 0 8.57E+07 5.63E+07 - - - 1.9526 0.972 230117_WJC_METTL3_WT_vs_EV_F04.14159.14159.2 4.82 14-Aug K.LLGPVLVK[136.11].Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 845.583 3.84 29643 14159 2 845.583132 423.7988 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 3056.5 - 2.31E+06 - - - 0.1857 - 1.06 0.102 - 100.2 1 2 0 0.0002 8 0 0 0 9.73E+08 2.54E+08 - - - -0.0299 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.14166.14166.2 0.141 12-Jul R.FTDILVR[166.11].H sp|O43143|DHX15_HUMAN 1 872.4995 1.08 29649 14166 2 872.501324 437.257 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 3057.3 - 2.04E+06 - - - 2.0642 - 1.519 0.281 - 180.2 1 2 0 0.0018 7 0 0 0 4.48E+08 4.13E+08 - - - 2.4405 0.9904 230117_WJC_METTL3_WT_vs_EV_F04.14169.14169.2 0.706 12-Jul R.SLILAMK[136.11].A sp|Q7Z353|HDX_HUMAN 1 782.4815 0.53 29651 14169 2 782.482441 392.248 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 8.47 3057.6 - 1.05E+06 - - - 1.1425 - 1.425 0.046 - 215.8 1 2 0 0.0009 7 0 0 0 1.48E+07 2.80E+07 - - - 0.5027 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.14171.14171.2 0.0398 22-Dec K.SPILVATAVAAR[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1177.7058 1.11 29653 14171 2 1177.705274 589.8602 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3057.9 - 231661 - - - -0.4704 - 2.558 0.369 - 392.6 1 2 0 -0.0006 12 0 0 0 5.51E+08 4.96E+08 - - - 4.2375 0.978 230117_WJC_METTL3_WT_vs_EV_F04.14175.14175.2 0.0475 26-May K.IFVGGLSPDTPEEK[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1495.765 1.54 29655 14175 2 1495.770385 748.8898 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3058.4 - 46900.6 - - - 3.6169 - 0.999 0.213 - 59.1 1 2 0 0.0054 14 0 0 0 7.24E+06 4.70E+06 - - - 0.61 0.9623 230117_WJC_METTL3_WT_vs_EV_F04.14176.14176.2 2.54 12-Jun R.TVPFLPK[136.11].Y sp|Q96EV8|DTBP1_HUMAN 1 808.4938 1.49 29656 14176 2 808.494693 405.2542 Dysbindin OS=Homo sapiens OX=9606 GN=DTNBP1 PE=1 SV=1 8.41 3058.5 - 614875 - - - 1.0724 - 1.098 0.064 - 96.1 3 2 0 0.0009 7 0 0 0 2.88E+07 1.93E+07 - - - -0.4035 0.9938 230117_WJC_METTL3_WT_vs_EV_F04.14197.14197.2 0.139 18-May K.LFPGSPAIYK.L "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|F8W705|F8W705_HUMAN,tr|C9JF75|C9JF75_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|C9J6W1|C9J6W1_HUMAN,tr|H0YBN8|H0YBN8_HUMAN,tr|C9J1W9|C9J1W9_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 17 1091.6015 3.86 29666 14197 2 1091.602157 546.808 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 8.59 3061.4 - 167842 - - - 0.5726 - 1.163 0.239 - 52.1 5 2 0 0.0006 10 0 0 0 4.68E+07 1.21E+07 - - - 0.9153 0.9926 230117_WJC_METTL3_WT_vs_EV_F04.14199.14199.2 0.222 16-Jun K.VLPLEEAYR.F sp|Q9H223|EHD4_HUMAN 1 1088.5866 2.34 29668 14199 2 1088.588297 545.3006 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 3061.6 - 264395 - - - 1.5497 - 1.205 0.15 - 103.6 1 2 0 0.0017 9 0 0 0 1.64E+08 7.03E+07 - - - 0.6879 1 230117_WJC_METTL3_WT_vs_EV_F04.14203.14203.2 0.000308 13/22 K.SPILVATAVAAR.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1167.6976 1.11 29670 14203 2 1167.699229 584.8561 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3062.1 - 2.41E+06 - - - 1.431 - 2.54 0.531 - 703.5 1 2 0 0.0017 12 0 0 0 5.51E+08 4.96E+08 - - - 5.4151 0.9942 230117_WJC_METTL3_WT_vs_EV_F04.14204.14204.2 7.85 14-Aug K.GIGLAIVR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 807.5206 0.92 29671 14204 2 807.52151 404.7676 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 3062.2 - 733430 - - - 1.1356 - 1.359 0.123 - 187.8 1 2 0 0.0009 8 0 0 0 3.93E+08 4.29E+08 - - - 0.8743 0.9829 230117_WJC_METTL3_WT_vs_EV_F04.14208.14208.2 0.867 12-Jul R.AWGALIK[136.11].E "sp|Q53F19|NCBP3_HUMAN,tr|K7ELP6|K7ELP6_HUMAN" 2 765.4629 0.08 29673 14208 2 765.464917 383.7387 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 8.8 3062.7 - 1.57E+06 - - - 2.6873 - 1.115 0.136 - 178.8 1 2 0 0.0021 7 0 0 0 2.85E+06 3.70E+07 - - - 0.3898 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.14209.14209.2 0.000913 14-Oct R.VPDVVLIK.K "sp|Q96D46|NMD3_HUMAN,tr|C9JA08|C9JA08_HUMAN" 2 881.5586 2.55 29674 14209 2 881.559718 441.7866 60S ribosomal export protein NMD3 OS=Homo sapiens OX=9606 GN=NMD3 PE=1 SV=1 5.81 3062.8 - 495966 - - - 1.2625 - 1.585 0.417 - 253.9 1 2 0 0.0011 8 0 0 0 3.25E+07 1.27E+07 - - - 3.5097 0.9949 230117_WJC_METTL3_WT_vs_EV_F04.14213.14213.2 0.479 14-Jun R.LLAMLEQK.N "sp|Q96EA4|SPDLY_HUMAN,tr|H0YBG5|H0YBG5_HUMAN" 2 944.5365 11.31 29676 14213 2 944.537733 473.2755 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 6 3063.3 - 1.07E+06 - - - 1.317 - 1.213 0.181 - 72.2 1 2 0 0.0012 8 0 0 0 2.82E+07 2.49E+06 - - - 0.9598 0.9806 230117_WJC_METTL3_WT_vs_EV_F04.14217.14217.2 0.584 14-Jun R.MLQAMGWK.E sp|P98175|RBM10_HUMAN 1 963.467 0.61 29678 14217 2 963.466512 482.7408 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 8.5 3063.8 - 309258 - - - -0.5366 - 1.045 0.179 - 72.2 1 2 0 -0.0005 8 0 0 0 7.90E+06 1.31E+07 - - - 0.4957 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.14219.14219.2 0.459 14-Aug R.LLLIATGK.R "sp|Q9NQW6|ANLN_HUMAN,tr|H7C1K5|H7C1K5_HUMAN" 2 827.548 0.04 29679 14219 2 827.548481 414.7813 Anillin OS=Homo sapiens OX=9606 GN=ANLN PE=1 SV=2 8.75 3064 - 709450 - - - 0.5329 - 1.602 0.121 - 138 1 2 0 0.0004 8 0 0 0 3.70E+07 8.61E+08 - - - 1.3558 0.8712 230117_WJC_METTL3_WT_vs_EV_F04.14221.14221.2 17.5 12-Jun K.ILAEELK[136.11].E "sp|O15050|TRNK1_HUMAN,tr|A0A2R8YEM9|A0A2R8YEM9_HUMAN" 2 822.4942 0.54 29681 14221 2 822.49721 412.2544 TPR and ankyrin repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=TRANK1 PE=2 SV=4 4.53 3064.3 - 1.28E+06 - - - 3.6353 - 1.107 0.022 - 77.4 2 2 0 0.003 7 0 0 0 4.36E+07 8.14E+07 - - - -0.6098 0.9824 230117_WJC_METTL3_WT_vs_EV_F04.14237.14237.2 0.144 12-May -.MFVSDFR.K "sp|O75419|CDC45_HUMAN,tr|A0A5F9ZH29|A0A5F9ZH29_HUMAN,tr|C9J911|C9J911_HUMAN,tr|C9K087|C9K087_HUMAN" 4 900.4164 1.62 29691 14237 2 900.41523 451.2155 Cell division control protein 45 homolog OS=Homo sapiens OX=9606 GN=CDC45 PE=1 SV=1 5.59 3066.3 - 360226 - - - -1.2705 - 1.162 0.187 - 70.5 1 2 0 -0.0011 7 0 0 0 1.59E+07 9.82E+06 - - - 0.8976 0.9919 230117_WJC_METTL3_WT_vs_EV_F04.14248.14248.2 0.15 16-Sep K.VLPLEEAYR[166.11].F sp|Q9H223|EHD4_HUMAN 1 1098.5949 2.49 29698 14248 2 1098.59442 550.3047 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 3067.6 - 1.14E+06 - - - -0.4187 - 1.258 0.187 - 225.4 1 2 0 -0.0005 9 0 0 0 1.61E+08 6.45E+07 - - - 1.0861 0.9777 230117_WJC_METTL3_WT_vs_EV_F04.14253.14253.2 0.926 12-Jul K.ALVLQLK.E "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 783.5218 1.08 29700 14253 2 783.522651 392.7682 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 8.8 3068.2 - 1.89E+06 - - - 1.0542 - 1.357 0.009 - 180 2 2 0 0.0008 7 0 0 0 4.71E+07 4.36E+07 - - - -0.06 0.9809 230117_WJC_METTL3_WT_vs_EV_F04.14270.14270.2 0.31 12-Jun K.IVQWDIR.S "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 928.5131 1.33 29709 14270 2 928.511041 465.2638 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.84 3070.2 - 478362 - - - -2.1648 - 1.384 0.163 - 99.2 1 2 0 -0.002 7 0 0 0 9.07E+06 6.80E+06 - - - 1.274 0.9919 230117_WJC_METTL3_WT_vs_EV_F04.14273.14273.2 0.0282 14-Jul K.VITMFVQR[166.11].Q "sp|P13010|XRCC5_HUMAN,tr|C9JZ81|C9JZ81_HUMAN,tr|H7C0H9|H7C0H9_HUMAN" 3 1002.556 1.06 29710 14273 2 1002.553312 502.2853 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 9.72 3070.6 - 552141 - - - -2.6732 - 1.435 0.301 - 125 1 2 0 -0.0027 8 0 0 0 7.20E+07 6.82E+07 - - - 2.3526 0.9972 230117_WJC_METTL3_WT_vs_EV_F04.14277.14277.2 0.168 16-Jul R.VLGVLEVSR.S "sp|Q9H0C8|ILKAP_HUMAN,tr|F8SNU7|F8SNU7_HUMAN,tr|H7C2I8|H7C2I8_HUMAN" 3 970.5811 3.75 29712 14277 2 970.582271 486.2978 Integrin-linked kinase-associated serine\threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1 5.97 3071.1 - 805009 - - - 1.1746 - 1.4 0.194 - 101.8 1 2 0 0.0011 9 0 0 0 2.99E+07 7.98E+06 - - - 1.447 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.14280.14280.2 4.66 18-Sep K.LPAVVTADLR.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1053.6182 2.14 29713 14280 2 1053.619233 527.8164 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.84 3071.5 - 121270 - - - 0.9377 - 1.805 0.111 - 197 1 2 0 0.001 10 0 0 0 4.15E+07 1.94E+07 - - - 1.509 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.14288.14288.2 0.0156 16-Oct R.LAEYYGLYR.D sp|Q96DV4|RM38_HUMAN 1 1146.571 1.19 29719 14288 2 1146.573574 574.2928 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3072.3 - 200657 - - - 2.2798 - 2.129 0.321 - 397.4 1 2 0 0.0026 9 0 0 0 3.49E+07 2.94E+07 - - - 3.5972 0.993 230117_WJC_METTL3_WT_vs_EV_F04.14292.14292.2 0.788 12-Jul K.LWNGLVK[136.11].V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 836.5 0.97 29721 14292 2 836.500197 419.2573 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 3072.9 - 984872 - - - 0.2666 - 1.15 0.194 - 92.5 1 2 0 0.0002 7 0 0 0 5.03E+07 5.18E+07 - - - 0.9167 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.14293.14293.2 5.54E-06 18-Sep R.VPLVAPEDLR[166.11].D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1117.6371 0.54 29722 14293 2 1117.636243 559.8258 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3073 - 548441 - - - -0.748 - 2.319 0.323 - 278.1 1 2 0 -0.0008 10 0 0 0 3.55E+08 6.56E+08 - - - 3.7743 0.98 230117_WJC_METTL3_WT_vs_EV_F04.14297.14297.2 6.13 12-May K.LWNGLVK.V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 828.4858 1.03 29724 14297 2 828.486616 415.2502 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 3073.5 - 795597 - - - 1.0163 - 1.067 0.133 - 54.3 3 2 0 0.0008 7 0 0 0 5.33E+07 5.19E+07 - - - 0.0154 0.9421 230117_WJC_METTL3_WT_vs_EV_F04.14298.14298.2 0.394 12-Jul R.LWEAGWK[136.11].Q sp|Q9H0D6|XRN2_HUMAN 1 896.4636 0.93 29725 14298 2 896.467686 449.2391 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 6 3073.6 - 540607 - - - 4.5713 - 1.313 0.063 - 157.8 1 2 0 0.0041 7 0 0 0 1.93E+08 2.07E+08 - - - 0.3679 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.14299.14299.2 0.113 14-Jun K.VLLSALER[166.11].L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 909.5523 2.55 29726 14299 2 909.554231 455.7834 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.97 3073.7 - 929300 - - - 2.1373 - 1.395 0.23 - 95.3 1 2 0 0.0019 8 0 0 0 3.92E+08 1.54E+08 - - - 1.7432 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.14300.14300.2 0.545 16-Oct R.LAEYYGLYR[166.11].D sp|Q96DV4|RM38_HUMAN 1 1156.5792 1.19 29727 14300 2 1156.580126 579.2969 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3073.9 - 437756 - - - 0.7747 - 1.783 0.14 - 417.4 1 2 0 0.0009 9 0 0 0 3.49E+07 2.94E+07 - - - 1.7478 0.8817 230117_WJC_METTL3_WT_vs_EV_F04.14304.14304.2 0.525 12-Sep S.VGAEIQR.L tr|D6RFZ9|D6RFZ9_HUMAN 1 771.4239 1.15 29729 14304 2 771.42392 386.7192 Receptor of-activated protein C kinase 1 (Fragment) OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=8 5.97 3074.4 - 380567 - - - 0.0233 - 1.763 0.189 - 229.2 1 1 0 0 7 0 0 0 1.32E+07 1.15E+07 - - - 2.2336 0.9921 230117_WJC_METTL3_WT_vs_EV_F04.14311.14311.2 0.202 14-Jun K.DGETIELR.L "sp|P20062|TCO2_HUMAN,tr|B5MBX2|B5MBX2_HUMAN,tr|F8WE86|F8WE86_HUMAN" 3 931.4611 3.33 29734 14311 2 931.463412 466.7378 Transcobalamin-2 OS=Homo sapiens OX=9606 GN=TCN2 PE=1 SV=3 4.14 3075.2 - 431099 - - - 2.509 - 1.304 0.14 - 107.3 1 2 0 0.0023 8 0 0 0 1.63E+07 4.88E+06 - - - 0.8749 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.14314.14314.2 0.0642 16-Jun K.LLVLDPAQR.L sp|P50750|CDK9_HUMAN 1 1023.6077 1.8 29736 14314 2 1023.609672 512.8111 Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3 5.84 3075.6 - 495294 - - - 1.9461 - 1.436 0.298 - 98 1 2 0 0.002 9 0 0 0 2.85E+07 1.58E+07 - - - 2.2883 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.14333.14333.2 0.0342 14-Aug K.VLETFLAK.S "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 919.5379 1.38 29748 14333 2 919.539432 460.7762 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 5.97 3078 - 1.25E+06 - - - 1.6998 - 1.473 0.262 - 192.7 1 2 0 0.0016 8 0 0 0 4.85E+07 3.53E+07 - - - 2.1437 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.14335.14335.2 0.00282 16-Oct K.LNSLAIGLR.Q sp|P54886|P5CS_HUMAN 1 955.5815 1.56 29750 14335 2 955.584326 478.798 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3078.1 - 556941 - - - 2.994 - 2.185 0.391 - 293 1 2 0 0.0029 9 0 0 0 4.43E+07 2.85E+07 - - - 4.1893 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.14336.14336.2 0.0135 16-Aug K.LNSLAIGLR[166.11].Q sp|P54886|P5CS_HUMAN 1 965.5897 1.6 29751 14336 2 965.592385 483.8021 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3078.2 - 444265 - - - 2.7444 - 1.989 0.335 - 167.5 1 2 0 0.0027 9 0 0 0 4.65E+07 2.91E+07 - - - 3.5038 0.995 230117_WJC_METTL3_WT_vs_EV_F04.14339.14339.2 1.28 12-Jun R.FPLVSVR.N "sp|Q8NFF5|FAD1_HUMAN,tr|Q5T196|Q5T196_HUMAN" 2 816.4858 1.58 29752 14339 2 816.487494 409.2502 FAD synthase OS=Homo sapiens OX=9606 GN=FLAD1 PE=1 SV=1 9.75 3078.6 - 473488 - - - 2.1066 - 1.337 0.152 - 95.5 1 2 0 0.0017 7 0 0 0 5.41E+07 3.43E+07 - - - 1.0834 0.984 230117_WJC_METTL3_WT_vs_EV_F04.14351.14351.2 1.45 16-Jun K.ILLNDYEYR.Q "sp|Q9Y2D8|ADIP_HUMAN,tr|S4R403|S4R403_HUMAN" 2 1197.603 2.05 29762 14351 2 1197.605503 599.8088 Afadin- and alpha-actinin-binding protein OS=Homo sapiens OX=9606 GN=SSX2IP PE=1 SV=3 4.37 3080.1 - 47039.7 - - - 2.0992 - 1.096 0.127 - 55.3 1 2 0 0.0025 9 0 0 0 1.01E+06 4.95E+05 - - - 0.2434 1 230117_WJC_METTL3_WT_vs_EV_F04.14360.14360.2 0.000219 20-Oct K.DAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1160.5561 46.39 29769 14360 2 1160.558751 581.2853 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.92 3081.1 - 666048 - - - 2.286 - 2.302 0.458 - 400.8 1 2 0 0.0027 11 0 0 0 7.71E+06 1.66E+05 - - - 4.6785 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.14362.14362.2 0.00178 28-Sep R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 0.4 29771 14362 2 1410.785291 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3081.4 - 230599 - - - 1.5686 - 1.767 0.325 - 139.7 1 2 0 0.0022 15 0 0 0 6.77E+06 1.68E+07 - - - 2.8404 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.14367.14367.2 0.107 12-Jul K.LSAFAFK.Q sp|O75717|WDHD1_HUMAN 1 782.4327 1.83 29774 14367 2 782.434266 392.2236 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 8.75 3081.9 - 466802 - - - 2.0321 - 1.469 0.234 - 105.7 1 2 0 0.0016 7 0 0 0 1.97E+07 1.07E+07 - - - 1.9874 0.9949 230117_WJC_METTL3_WT_vs_EV_F04.14372.14372.2 0.203 12-Jun K.LSAFAFK[136.11].Q sp|O75717|WDHD1_HUMAN 1 790.4469 1.83 29777 14372 2 790.449392 396.2307 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 8.75 3082.6 - 459682 - - - 3.183 - 1.49 0.165 - 72.1 1 2 0 0.0025 7 0 0 0 1.96E+07 1.07E+07 - - - 1.5224 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.14373.14373.2 0.00158 26-Nov K.VPQVSTPTLVEVSR.N "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1510.8355 999 29778 14373 2 1510.8404 756.425 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.97 3082.7 - 218452 - - - 3.2379 - 2.125 0.494 - 299.6 1 2 0 0.0049 14 0 0 0 1.53E+06 0.00E+00 - - - 4.5797 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.14376.14376.2 0.0115 16-Sep R.ILALDC[160.03]GLK[136.11].Y "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1009.5722 1.87 29780 14376 2 1009.575396 505.7934 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.83 3083.1 - 2.43E+06 - - - 3.2123 - 1.759 0.291 - 196.2 1 2 0 0.0032 9 0 0 0 8.43E+07 4.50E+07 - - - 2.8231 0.949 230117_WJC_METTL3_WT_vs_EV_F04.14377.14377.2 0.752 16-May K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 12.15 29781 14377 2 1014.537873 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3083.2 - 310635 - - - 3.2508 - 1.176 0.085 - 44.9 4 2 0 0.0033 9 0 0 0 6.46E+06 5.32E+05 - - - -0.1321 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.14386.14386.2 0.0405 14-Aug K.NIELAVMR.R "sp|O14818|PSA7_HUMAN,tr|H0Y586|H0Y586_HUMAN" 2 944.5113 2.16 29788 14386 2 944.513589 473.2629 Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1 6 3084.2 - 787347 - - - 2.3843 - 1.543 0.221 - 220.1 1 2 0 0.0023 8 0 0 0 2.86E+07 1.32E+07 - - - 1.9807 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.14404.14404.2 2.85 12-Aug R.VLGLLER.S "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 798.4963 1.53 29800 14404 2 798.498528 400.2554 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 5.97 3086.6 - 2.50E+06 - - - 2.7414 - 1.583 0.156 - 227.5 1 2 0 0.0022 7 0 0 0 4.85E+07 3.18E+07 - - - 1.6479 1 230117_WJC_METTL3_WT_vs_EV_F04.14407.14407.2 6.33E-05 18-Oct R.IATANMLGIR.K sp|Q9NX20|RM16_HUMAN 1 1058.5907 1.06 29803 14407 2 1058.595217 530.3026 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3086.9 - 608985 - - - 4.3142 - 2.427 0.5 - 311.9 1 2 0 0.0046 10 0 0 0 4.13E+07 3.88E+07 - - - 5.2075 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.14408.14408.2 0.00482 18-Dec R.IATANMLGIR[166.11].K sp|Q9NX20|RM16_HUMAN 1 1068.5989 1.17 29804 14408 2 1068.601895 535.3067 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3087 - 515586 - - - 2.784 - 1.912 0.388 - 491.4 1 2 0 0.003 10 0 0 0 4.10E+07 3.50E+07 - - - 3.715 0.9869 230117_WJC_METTL3_WT_vs_EV_F04.14409.14409.2 0.302 18-Aug K.IMLVEPPVAK[136.11].V sp|P18583|SON_HUMAN 1 1103.6504 1.76 29805 14409 2 1103.654754 552.8325 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3087.1 - 263621 - - - 3.9424 - 1.315 0.184 - 105 1 2 0 0.0044 10 0 0 0 8.53E+06 4.85E+06 - - - 1.163 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.14416.14416.2 0.201 22-Sep K.SPILVATAVAAR[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1177.7058 1.11 29809 14416 2 1177.704658 589.8602 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3088 - 124502 - - - -0.9935 - 2.2 0.255 - 178.2 1 2 0 -0.0012 12 0 0 0 5.51E+08 4.96E+08 - - - 2.9986 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.14422.14422.3 0.000309 Dec-48 R.LVHPGVAEVVFVK[136.11].K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1400.8271 1.13 29812 14422 3 1400.832647 467.9497 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 3088.8 - 438830 - - - 3.9441 - 2.2 0.405 - 176.9 1 2 0 0.0055 13 0 0 0 1.86E+07 1.66E+07 - - - 5.1916 0.9963 230117_WJC_METTL3_WT_vs_EV_F04.14433.14433.2 4.32 12-May K.RIYGGFK[136.11].S sp|Q14520|HABP2_HUMAN 1 847.4796 - 29819 14433 2 847.480361 424.7471 Hyaluronan-binding protein 2 OS=Homo sapiens OX=9606 GN=HABP2 PE=1 SV=1 9.99 3090.1 - 1.40E+06 - - - 0.9298 - 1.319 0.214 - 62.8 4 2 0 0.0008 7 0 0 0 - - - - - 1.2297 0.9803 230117_WJC_METTL3_WT_vs_EV_F04.14436.14436.2 1.27 18-May R.SLVVPAYAYR.K sp|Q9Y3R4|NEUR2_HUMAN 1 1137.6182 11.84 29822 14436 2 1137.621212 569.8164 Sialidase-2 OS=Homo sapiens OX=9606 GN=NEU2 PE=1 SV=2 8.31 3090.5 - 94800.2 - - - 2.6081 - 1.315 0.091 - 54.2 3 2 0 0.003 10 0 0 0 2.22E+06 1.87E+05 - - - 0.2634 0.9652 230117_WJC_METTL3_WT_vs_EV_F04.14439.14439.2 0.897 16-Oct R.AGVIFPVGR[166.11].L "sp|Q9P0M6|H2AW_HUMAN,sp|O75367|H2AY_HUMAN,tr|A0A7I2YQD6|A0A7I2YQD6_HUMAN,tr|B4DJC3|B4DJC3_HUMAN,tr|A0A7I2V412|A0A7I2V412_HUMAN,tr|Q5SQT3|Q5SQT3_HUMAN,tr|A0A7I2V423|A0A7I2V423_HUMAN,tr|A0A7I2V2N7|A0A7I2V2N7_HUMAN,tr|A0A7I2V4D9|A0A7I2V4D9_HUMAN,tr|D6RCF2|D6RCF2_HUMAN,tr|A0A7I2V6E9|A0A7I2V6E9_HUMAN,tr|A0A7I2YQB9|A0A7I2YQB9_HUMAN,tr|A0A7I2YQR8|A0A7I2YQR8_HUMAN" 13 924.5421 0.63 29823 14439 2 924.545555 463.2783 Core histone macro-H2A.2 OS=Homo sapiens OX=9606 GN=MACROH2A2 PE=1 SV=3 9.79 3091 - 1.12E+06 - - - 3.7835 - 1.433 0.038 - 353.8 1 2 0 0.0035 9 0 0 0 4.28E+07 6.76E+07 - - - 0.3614 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.14441.14441.2 0.0232 14-Sep K.VPGIFISR[166.11].M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 897.5312 0.1 29825 14441 2 897.534269 449.7729 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3091.2 - 1.05E+06 - - - 3.4662 - 1.62 0.297 - 251.2 1 2 0 0.0031 8 0 0 0 3.48E+07 3.63E+08 - - - 2.6886 0.9823 230117_WJC_METTL3_WT_vs_EV_F04.14442.14442.2 0.434 14-Aug R.IGFIEEVK.A sp|Q96P63|SPB12_HUMAN 1 933.5171 27.96 29826 14442 2 933.520473 467.7658 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 4.53 3091.3 - 899805 - - - 3.5768 - 1.429 0.086 - 124.2 1 2 0 0.0033 8 0 0 0 1.43E+08 5.10E+06 - - - 0.7518 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.14446.14446.2 0.00298 18-Jun K.LFPGSPAIYK.L "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|F8W705|F8W705_HUMAN,tr|C9JF75|C9JF75_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|C9J6W1|C9J6W1_HUMAN,tr|H0YBN8|H0YBN8_HUMAN,tr|C9J1W9|C9J1W9_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 17 1091.6015 1.81 29828 14446 2 1091.603805 546.808 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 8.59 3091.8 - 242526 - - - 2.0823 - 1.38 0.32 - 96.3 1 2 0 0.0023 10 0 0 0 1.33E+07 7.32E+06 - - - 2.3028 0.9816 230117_WJC_METTL3_WT_vs_EV_F04.14447.14447.2 0.318 20-Jun M.VPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1175.7278 2.26 29829 14447 2 1175.731192 588.8712 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.72 3091.9 - 128557 - - - 2.8893 - 1.264 0.143 - 52.8 5 2 0 0.0034 11 0 0 0 1.21E+07 5.38E+06 - - - 0.4177 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.14449.14449.2 0.000997 16-Oct K.TLAIELAPR[166.11].N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 992.5894 -1 29831 14449 2 992.590174 497.302 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3092.1 - 286058 - - - 0.7788 - 1.732 0.411 - 326.5 1 2 0 0.0008 9 0 0 0 0.00E+00 0.00E+00 - - - 3.6655 0.9797 230117_WJC_METTL3_WT_vs_EV_F04.14453.14453.2 0.0753 22-Jun K.SPILVATAVAAR.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1167.6976 1.11 29834 14453 2 1167.699854 584.8561 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3092.6 - 77768.6 - - - 1.9663 - 1.333 0.053 - 47.3 2 2 0 0.0023 12 0 0 0 5.50E+08 4.95E+08 - - - 0.0535 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.14457.14457.2 0.0887 12-Jun R.FWETLDR.Y "sp|Q6P1J9|CDC73_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN" 2 965.4607 1.87 29837 14457 2 965.463311 483.7376 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 4.37 3093.1 - 603685 - - - 2.7241 - 1.329 0.327 - 123.6 1 2 0 0.0026 7 0 0 0 4.04E+07 2.16E+07 - - - 2.3566 0.998 230117_WJC_METTL3_WT_vs_EV_F04.14458.14458.2 0.00765 20-Jul K.LIPGPLSPVAR[166.11].G sp|P48634|PRC2A_HUMAN 1 1128.6894 1.27 29838 14458 2 1128.693194 565.352 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3093.2 - 301119 - - - 3.318 - 1.514 0.314 - 129.7 1 2 0 0.0037 11 0 0 0 4.14E+08 3.27E+08 - - - 2.481 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.14459.14459.2 0.00474 16-Jul R.FLAEEGFYK[136.11].F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1110.5477 1.21 29839 14459 2 1110.550582 556.2811 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3093.4 - 249181 - - - 2.5843 - 1.645 0.383 - 117.6 1 2 0 0.0029 9 0 0 0 9.77E+07 8.06E+07 - - - 3.3089 0.9941 230117_WJC_METTL3_WT_vs_EV_F04.14462.14462.2 0.0447 14-Aug K.VPGIFISR.M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 887.5229 0.44 29840 14462 2 887.524181 444.7687 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3093.8 - 2.72E+06 - - - 1.4569 - 1.5 0.08 - 240.2 1 2 0 0.0013 8 0 0 0 8.08E+07 1.84E+08 - - - 0.8543 0.999 230117_WJC_METTL3_WT_vs_EV_F04.14463.14463.2 0.0356 16-Oct R.VLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 969.5859 1.44 29841 14463 2 969.588643 485.8002 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3093.8 - 1.36E+06 - - - 2.8476 - 1.96 0.275 - 314.6 1 2 0 0.0028 9 0 0 0 8.53E+08 5.92E+08 - - - 3.0181 0.959 230117_WJC_METTL3_WT_vs_EV_F04.14464.14464.2 0.0933 14-Sep M.PTPVILLK.E "sp|Q99832|TCPH_HUMAN,tr|A0A0D9SG95|A0A0D9SG95_HUMAN,tr|F8WBP8|F8WBP8_HUMAN" 3 879.5793 12.95 29842 14464 2 879.580997 440.7969 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 9.18 3093.9 - 758774 - - - 1.8839 - 1.612 0.371 - 264.9 1 1 0 0.0017 8 0 0 0 1.27E+08 9.80E+06 - - - 3.2207 0.9972 230117_WJC_METTL3_WT_vs_EV_F04.14465.14465.2 3.80E-05 16-Aug R.FLAEEGFYK.F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1102.5335 1.21 29843 14465 2 1102.539445 552.274 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3094.1 - 383561 - - - 5.3812 - 1.58 0.498 - 171.4 1 2 0 0.0059 9 0 0 0 9.77E+07 8.06E+07 - - - 4.0407 0.9925 230117_WJC_METTL3_WT_vs_EV_F04.14470.14470.2 0.998 16-Sep R.AGVIFPVGR.L "sp|Q9P0M6|H2AW_HUMAN,sp|O75367|H2AY_HUMAN,tr|A0A7I2YQD6|A0A7I2YQD6_HUMAN,tr|B4DJC3|B4DJC3_HUMAN,tr|A0A7I2V412|A0A7I2V412_HUMAN,tr|Q5SQT3|Q5SQT3_HUMAN,tr|A0A7I2V423|A0A7I2V423_HUMAN,tr|A0A7I2V2N7|A0A7I2V2N7_HUMAN,tr|A0A7I2V4D9|A0A7I2V4D9_HUMAN,tr|D6RCF2|D6RCF2_HUMAN,tr|A0A7I2V6E9|A0A7I2V6E9_HUMAN,tr|A0A7I2YQB9|A0A7I2YQB9_HUMAN,tr|A0A7I2YQR8|A0A7I2YQR8_HUMAN" 13 914.5338 0.59 29847 14470 2 914.536146 458.2742 Core histone macro-H2A.2 OS=Homo sapiens OX=9606 GN=MACROH2A2 PE=1 SV=3 9.79 3094.7 - 1.80E+06 - - - 2.5795 - 1.628 0.067 - 316.2 1 2 0 0.0024 9 0 0 0 3.95E+07 6.70E+07 - - - 0.9451 0.9957 230117_WJC_METTL3_WT_vs_EV_F04.14475.14475.2 2.14 12-Sep K.IGIEIIK[136.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 792.52 2.04 29851 14475 2 792.521216 397.2673 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3095.1 - 1.08E+06 - - - 1.4826 - 1.987 0.002 - 193.9 2 2 0 0.0012 7 0 0 0 1.60E+10 7.84E+09 - - - 1.0965 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.14476.14476.2 0.106 12-Sep R.IAAYLFK.G "sp|Q00610|CLH1_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|J3KRF5|J3KRF5_HUMAN" 5 824.4796 1.11 29852 14476 2 824.481662 413.2471 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.59 3095.3 - 999540 - - - 2.4694 - 1.911 0.285 - 215.5 1 2 0 0.002 7 0 0 0 3.00E+08 2.71E+08 - - - 3.1974 0.9926 230117_WJC_METTL3_WT_vs_EV_F04.14480.14480.2 0.109 18-Jun K.WTLLQEQGTK.T "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1202.6295 999 29856 14480 2 1202.630152 602.322 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6 3095.7 - 188375 - - - 0.5105 - 1.317 0.134 - 77 1 2 0 0.0006 10 0 0 0 1.81E+06 0.00E+00 - - - 0.7991 0.9548 230117_WJC_METTL3_WT_vs_EV_F04.14481.14481.2 2.11 18-Apr K.FMQASEDLLK[136.11].E "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 1188.594 5.52 29857 14481 2 1188.595207 595.3043 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.37 3095.9 - 103661 - - - 1.0071 - 0.917 0.174 - 25 22 2 0 0.0012 10 0 0 0 1.73E+07 3.14E+06 - - - -0.5157 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.14485.14485.2 0.0333 14-Jun K.QFFVAVER[166.11].E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1004.5319 0.92 29859 14485 2 1004.532264 503.2732 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 6 3096.4 - 411833 - - - 0.3763 - 1.455 0.308 - 121.7 1 2 0 0.0004 8 0 0 0 5.50E+07 6.00E+07 - - - 2.4468 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.14489.14489.2 0.000226 20-Aug K.LIPGPLSPVAR.G sp|P48634|PRC2A_HUMAN 1 1118.6812 1.27 29861 14489 2 1118.682735 560.3479 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3096.9 - 718541 - - - 1.3909 - 1.597 0.487 - 260.2 1 2 0 0.0016 11 0 0 0 4.14E+08 3.27E+08 - - - 3.9039 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.14502.14502.2 0.0289 20-Aug K.ILATTPSAVFR.V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1174.671 1.9 29870 14502 2 1174.673317 588.3428 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3098.5 - 142825 - - - 1.9648 - 1.474 0.301 - 162.9 1 2 0 0.0023 11 0 0 0 4.88E+07 2.57E+07 - - - 2.313 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.14515.14515.2 0.171 14-Aug R.ELVITIAR[166.11].E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 923.5679 1.25 29876 14515 2 923.568921 462.7912 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3100.2 - 3.12E+06 - - - 1.0654 - 1.36 0.212 - 236.1 1 2 0 0.001 8 0 0 0 3.19E+08 2.55E+08 - - - 1.5339 1 230117_WJC_METTL3_WT_vs_EV_F04.14516.14516.3 1.05E-07 13/128 R.SDSPVPTAPTSGGPKPSTASAVPELATDPELEK.K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3232.5987 7.96 29877 14516 3 3232.600628 1078.5402 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3100.3 - 270841 - - - 0.597 - 2.542 0.575 - 88.7 1 2 0 0.0019 33 0 0 0 1.45E+07 1.82E+06 - - - 7.0965 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.14522.14522.2 0.00532 20-Aug K.ILATTPSAVFR[166.11].V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1184.6793 1.9 29881 14522 2 1184.682624 593.3469 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3101.1 - 326605 - - - 2.8235 - 1.481 0.245 - 153.3 1 2 0 0.0033 11 0 0 0 4.88E+07 2.57E+07 - - - 1.9119 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.14525.14525.2 0.137 14-Aug R.IGFIEEVK.A sp|Q96P63|SPB12_HUMAN 1 933.5171 27.96 29882 14525 2 933.517732 467.7658 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 4.53 3101.5 - 3.19E+06 - - - 0.6406 - 1.409 0.207 - 148.1 1 2 0 0.0006 8 0 0 0 1.43E+08 5.10E+06 - - - 1.6038 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.14527.14527.2 0.00256 14-Aug K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 0.89 29883 14527 2 895.478471 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3101.7 - 1.05E+06 - - - -2.1028 - 1.466 0.34 - 164.9 1 2 0 -0.0019 8 0 0 0 4.08E+07 4.60E+07 - - - 2.7054 0.9969 230117_WJC_METTL3_WT_vs_EV_F04.14534.14534.2 0.0105 18-Dec K.AIITALGVER.R sp|Q92616|GCN1_HUMAN 1 1041.6182 1.78 29888 14534 2 1041.616964 521.8164 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 6.05 3102.7 - 1.57E+06 - - - -1.2298 - 2.205 0.156 - 466.5 1 2 0 -0.0013 10 0 0 0 5.89E+07 3.31E+07 - - - 2.4 0.9656 230117_WJC_METTL3_WT_vs_EV_F04.14543.14543.2 0.289 14-Jul R.GLVGEIIK.R "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 827.5117 1.01 29894 14543 2 827.510451 414.7631 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6 3103.7 - 5.68E+06 - - - -1.4538 - 1.33 0.08 - 164.1 1 2 0 -0.0012 8 0 0 0 4.58E+09 4.52E+09 - - - 0.4916 0.8897 230117_WJC_METTL3_WT_vs_EV_F04.14545.14545.2 0.68 12-Jun K.ELLPEIR.E "sp|P49321|NASP_HUMAN,tr|H0YDS9|H0YDS9_HUMAN,tr|Q5T624|Q5T624_HUMAN,tr|H0YF33|H0YF33_HUMAN,tr|E9PRH9|E9PRH9_HUMAN" 5 868.5018 3.41 29896 14545 2 868.500279 435.2582 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 4.53 3103.9 - 454427 - - - -1.772 - 1.214 0.02 - 150.5 1 2 0 -0.0015 7 0 0 0 7.03E+07 2.06E+07 - - - -0.1973 0.9957 230117_WJC_METTL3_WT_vs_EV_F04.14547.14547.2 0.351 14-Aug R.ELVITIAR.E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 913.5597 1.25 29897 14547 2 913.558624 457.7871 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3104.1 - 1.03E+07 - - - -1.1417 - 1.61 0.209 - 374.5 1 2 0 -0.001 8 0 0 0 3.19E+08 2.55E+08 - - - 2.0206 0.9784 230117_WJC_METTL3_WT_vs_EV_F04.14551.14551.2 0.000368 12-Aug K.VDFVIPK.E "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 816.4745 0.24 29898 14551 2 816.470306 409.2445 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.81 3104.7 - 3.23E+06 - - - -5.1869 - 1.534 0.355 - 254 1 2 0 -0.0042 7 0 0 0 7.78E+07 3.25E+08 - - - 3.0175 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.14553.14553.2 0.0008 18-Sep K.IMLVEPPVAK.V sp|P18583|SON_HUMAN 1 1095.6362 1.64 29900 14553 2 1095.635093 548.8254 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3105 - 1.02E+06 - - - -1.0131 - 1.966 0.316 - 253.2 1 2 0 -0.0011 10 0 0 0 3.42E+07 2.09E+07 - - - 3.2616 0.9581 230117_WJC_METTL3_WT_vs_EV_F04.14562.14562.2 1.63 16-May R.VYSYALALK.H "sp|Q9UKK9|NUDT5_HUMAN,tr|A6NFX8|A6NFX8_HUMAN" 2 1026.575 3.24 29904 14562 2 1026.576373 514.2948 ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1 8.47 3106.2 - 970126 - - - 1.354 - 1.092 0.059 - 64.4 3 2 0 0.0014 9 0 0 0 3.72E+07 1.15E+07 - - - -0.4822 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.14566.14566.2 0.0297 16-Nov R.GSPLLIGVR.S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 910.56 1.5 29907 14566 2 910.560201 456.2873 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3106.5 - 1.90E+06 - - - 0.2185 - 1.754 0.402 - 565.4 1 2 0 0.0002 9 0 0 0 1.87E+08 1.25E+08 - - - 3.6357 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.14567.14567.2 0.0249 16-Oct R.GSPLLIGVR[166.11].S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 920.5683 1.5 29908 14567 2 920.568432 461.2914 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3106.6 - 1.44E+06 - - - 0.1738 - 2.061 0.396 - 449.3 1 2 0 0.0002 9 0 0 0 1.87E+08 1.25E+08 - - - 4.058 0.9165 230117_WJC_METTL3_WT_vs_EV_F04.14572.14572.2 3.73 12-Jun R.LILQIGR.G "sp|Q9NP73|ALG13_HUMAN,tr|A0A096LNJ4|A0A096LNJ4_HUMAN,tr|A0A087WX43|A0A087WX43_HUMAN,tr|A0A087WTT9|A0A087WTT9_HUMAN,tr|D6RE84|D6RE84_HUMAN,tr|A0A096LP10|A0A096LP10_HUMAN,tr|A0A096LNL2|A0A096LNL2_HUMAN,tr|A0A1B0GVW6|A0A1B0GVW6_HUMAN" 8 811.528 2.45 29911 14572 2 811.527618 406.7713 Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 OS=Homo sapiens OX=9606 GN=ALG13 PE=1 SV=2 9.75 3107.2 - 313684 - - - -0.4374 - 0.937 0.085 - 76.9 1 2 0 -0.0004 7 0 0 0 1.55E+07 6.35E+06 - - - -0.5375 0.9045 230117_WJC_METTL3_WT_vs_EV_F04.14578.14578.2 0.0776 12-Jun R.IFFVSAK.E "sp|O95140|MFN2_HUMAN,sp|Q8IWA4|MFN1_HUMAN,tr|A0A6Q8PGV8|A0A6Q8PGV8_HUMAN,tr|H7C5H5|H7C5H5_HUMAN,tr|A0A6Q8PFJ4|A0A6Q8PFJ4_HUMAN,tr|A0A6Q8PGA3|A0A6Q8PGA3_HUMAN,tr|A0A6Q8PGS9|A0A6Q8PGS9_HUMAN" 7 810.464 0.56 29914 14578 2 810.459876 406.2393 Mitofusin-2 OS=Homo sapiens OX=9606 GN=MFN2 PE=1 SV=3 8.75 3108 - 570624 - - - -5.0588 - 1.382 0.177 - 106.8 1 2 0 -0.0041 7 0 0 0 1.50E+07 2.67E+07 - - - 1.3722 0.9035 230117_WJC_METTL3_WT_vs_EV_F04.14580.14580.2 0.276 12-Aug S.PLLIGVR[166.11].S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,sp|Q9UP38|FZD1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 6 776.5148 1.6 29915 14580 2 776.515482 389.2647 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 10.18 3108.2 - 164464 - - - 0.9053 - 1.765 0.174 - 173.5 1 1 0 0.0007 7 0 0 0 1.48E+07 9.26E+06 - - - 2.1262 0.998 230117_WJC_METTL3_WT_vs_EV_F04.14584.14584.2 0.0224 12-Jun R.FPYYLSR.H sp|Q8NAF0|ZN579_HUMAN 1 944.4756 1.07 29917 14584 2 944.475735 473.2451 Zinc finger protein 579 OS=Homo sapiens OX=9606 GN=ZNF579 PE=1 SV=2 8.59 3108.7 - 131659 - - - 0.1398 - 1.45 0.243 - 87.1 1 2 0 0.0001 7 0 0 0 3.50E+07 3.27E+07 - - - 2.0131 0.932 230117_WJC_METTL3_WT_vs_EV_F04.14587.14587.2 1.8 12-Jul R.TLDTFLR[166.11].S sp|Q96SK2|TM209_HUMAN 1 874.4788 1.52 29918 14587 2 874.480539 438.2467 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 5.5 3109.1 - 661964 - - - 2.0023 - 0.979 0.04 - 166.7 1 2 0 0.0018 7 0 0 0 4.95E+07 3.26E+07 - - - -0.7314 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.14595.14595.2 0.117 12-Sep R.TLDTFLR.S sp|Q96SK2|TM209_HUMAN 1 864.4705 1.52 29922 14595 2 864.470073 433.2425 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 5.5 3110 - 985910 - - - -0.5148 - 1.497 0.248 - 260 1 2 0 -0.0004 7 0 0 0 4.95E+07 3.26E+07 - - - 2.151 0.9942 230117_WJC_METTL3_WT_vs_EV_F04.14596.14596.2 0.596 14-Aug K.LITDEFVK[136.11].Q "sp|Q12816|TROP_HUMAN,sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN,tr|A0A087X070|A0A087X070_HUMAN,tr|G5E9N2|G5E9N2_HUMAN" 6 971.5419 1.16 29923 14596 2 971.541462 486.7782 Trophinin OS=Homo sapiens OX=9606 GN=TRO PE=1 SV=3 4.37 3110.1 - 761496 - - - -0.4488 - 1.451 0.162 - 129.8 1 2 0 -0.0004 8 0 0 0 2.50E+08 2.15E+08 - - - 1.3601 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.14600.14600.2 0.00369 16-Sep K.FVGNIYTLK[136.11].C "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1061.6001 2.04 29925 14600 2 1061.600353 531.8073 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3110.6 - 936744 - - - 0.2553 - 1.691 0.486 - 191 1 2 0 0.0003 9 0 0 0 9.41E+07 4.62E+07 - - - 4.1503 0.9954 230117_WJC_METTL3_WT_vs_EV_F04.14607.14607.2 0.026 16-Jul K.EGLVMVEVR[166.11].K sp|Q7KZF4|SND1_HUMAN 1 1040.5564 142.96 29931 14607 2 1040.555965 521.2855 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.53 3111.3 - 205721 - - - -0.4046 - 1.252 0.249 - 95 1 2 0 -0.0004 9 0 0 0 6.93E+08 4.85E+06 - - - 1.5302 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.14612.14612.2 0.0705 16-Sep R.GSPLLIGVR[166.11].S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 920.5683 1.5 29934 14612 2 920.567986 461.2914 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3111.8 - 2.37E+06 - - - -0.3107 - 1.735 0.34 - 350.3 1 2 0 -0.0003 9 0 0 0 1.87E+08 1.25E+08 - - - 3.1462 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.14615.14615.2 0.000771 16-Aug R.MGPNIYELR.T "sp|Q9BPW8|NIPS1_HUMAN,tr|C9JDV8|C9JDV8_HUMAN,tr|H7C2U6|H7C2U6_HUMAN" 3 1091.5434 1.51 29935 14615 2 1091.545641 546.779 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.75 3112.2 - 376884 - - - 2.0851 - 1.825 0.415 - 259.7 1 2 0 0.0023 9 0 0 0 3.96E+07 2.62E+07 - - - 3.8459 0.9829 230117_WJC_METTL3_WT_vs_EV_F04.14618.14618.2 0.213 16-Jul K.LVTEPLVLK[136.11].S sp|O43896|KIF1C_HUMAN 1 1018.6518 0.88 29936 14618 2 1018.657076 510.3332 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 6 3112.6 - 876984 - - - 5.1961 - 1.385 0.226 - 141.1 1 2 0 0.0053 9 0 0 0 2.45E+07 2.79E+07 - - - 1.6508 0.9465 230117_WJC_METTL3_WT_vs_EV_F04.14624.14624.2 0.0066 18-Aug R.IINEPTAAAI.A "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 16 1011.5601 - 29941 14624 2 1011.560819 506.7873 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4 3113.4 - 2.82E+06 - - - 0.7493 - 1.501 0.364 - 116.4 1 1 0 0.0008 10 0 0 0 - - - - - 2.8629 0.9972 230117_WJC_METTL3_WT_vs_EV_F04.14629.14629.2 0.00109 14-Jun R.EFADFEYR[166.11].K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1085.4693 1.27 29944 14629 2 1085.46846 543.7419 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3114 - 497978 - - - -0.8153 - 1.427 0.284 - 158.6 1 2 0 -0.0009 8 0 0 0 1.34E+07 1.06E+07 - - - 2.2107 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.14630.14630.2 0.000529 14-Jun R.EFADFEYR.K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1075.4611 1.27 29945 14630 2 1075.462489 538.7378 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3114.1 - 455225 - - - 1.3148 - 1.532 0.522 - 175.9 1 2 0 0.0014 8 0 0 0 1.34E+07 1.06E+07 - - - 4.1826 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.14642.14642.2 0.0827 16-Jun K.LVTEPLVLK.S sp|O43896|KIF1C_HUMAN 1 1010.6376 0.65 29950 14642 2 1010.638445 506.3261 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 6 3115.7 - 981540 - - - 0.8529 - 1.219 0.317 - 69.4 1 2 0 0.0009 9 0 0 0 2.47E+07 3.79E+07 - - - 1.955 0.9952 230117_WJC_METTL3_WT_vs_EV_F04.14643.14643.2 1.27 14-Jun K.FYGELALK.K "sp|P78527|PRKDC_HUMAN,tr|F5GX40|F5GX40_HUMAN" 2 939.5066 1.19 29951 14643 2 939.507591 470.7606 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 3115.8 - 405782 - - - 1.0878 - 1.239 0.179 - 91.5 1 2 0 0.001 8 0 0 0 3.85E+07 3.24E+07 - - - 1.0091 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.14645.14645.2 0.00397 14-Oct R.YADLLLEK.E sp|Q99459|CDC5L_HUMAN 1 963.5277 1.16 29952 14645 2 963.52833 482.7711 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3116 - 5.37E+06 - - - 0.6559 - 1.79 0.388 - 257.5 1 2 0 0.0006 8 0 0 0 2.50E+08 2.15E+08 - - - 3.6625 0.9945 230117_WJC_METTL3_WT_vs_EV_F04.14653.14653.2 0.00372 18-Oct R.VVVDALSGLK[136.11].G "sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|F8WCN3|F8WCN3_HUMAN" 3 1007.6106 1.83 29956 14653 2 1007.616983 504.8126 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 5.81 3117 - 934132 - - - 6.2881 - 2.099 0.382 - 301.7 1 2 0 0.0063 10 0 0 0 7.27E+07 3.96E+07 - - - 3.9301 0.9739 230117_WJC_METTL3_WT_vs_EV_F04.14662.14662.2 0.495 14-Jul K.AVPLTVAK.S sp|Q96GM8|TOE1_HUMAN 1 797.5011 1.53 29963 14662 2 797.501575 399.7578 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 8.8 3118.2 - 329586 - - - 0.6081 - 1.369 0.025 - 117.3 4 2 0 0.0005 8 0 0 0 1.16E+07 7.60E+06 - - - -0.0962 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.14668.14668.2 0.00155 18-Oct K.GVAYTLLTPK[136.11].D "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1069.6263 2.31 29967 14668 2 1069.628526 535.8204 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.59 3119 - 380455 - - - 2.0839 - 1.503 0.387 - 263.5 1 2 0 0.0022 10 0 0 0 2.36E+07 1.02E+07 - - - 3.036 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.14672.14672.2 0.0283 14-Aug K.IIYIAPMR.S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 975.5576 1.28 29969 14672 2 975.559428 488.7861 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 3119.5 - 1.16E+06 - - - 1.9158 - 1.521 0.258 - 207.1 1 2 0 0.0019 8 0 0 0 8.23E+07 6.45E+07 - - - 2.2108 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.14676.14676.2 0.442 16-Sep K.LGIIGVVNR.S "sp|O00429|DNM1L_HUMAN,tr|F8VZ52|F8VZ52_HUMAN" 2 939.5866 1.58 29972 14676 2 939.587797 470.8006 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 9.75 3120 - 1.42E+06 - - - 1.3261 - 1.753 0.305 - 184.2 1 2 0 0.0012 9 0 0 0 6.03E+07 3.81E+07 - - - 2.9173 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.14682.14682.2 0.023 12-Aug R.TMLLLSR.S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 832.4841 2.03 29976 14682 2 832.484395 417.2493 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.41 3120.6 - 1.97E+06 - - - 0.4036 - 1.589 0.226 - 334.1 1 2 0 0.0003 7 0 0 0 7.62E+07 3.76E+07 - - - 2.1775 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.14690.14690.2 0.458 14-Sep K.IIYIAPMR[166.11].S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 985.5658 1.38 29981 14690 2 985.566912 493.7902 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 3121.5 - 2.45E+06 - - - 1.0989 - 1.562 0.195 - 255.8 1 2 0 0.0011 8 0 0 0 8.22E+07 5.93E+07 - - - 1.8259 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.14694.14694.2 0.0128 14-Jul K.LLESDYFR.Y "sp|Q96HE7|ERO1A_HUMAN,tr|G3V503|G3V503_HUMAN,tr|G3V3E6|G3V3E6_HUMAN" 3 1041.5131 1.92 29983 14694 2 1041.511729 521.7638 ERO1-like protein alpha OS=Homo sapiens OX=9606 GN=ERO1A PE=1 SV=2 4.37 3121.9 - 248503 - - - -1.3269 - 1.476 0.385 - 131.9 1 2 0 -0.0014 8 0 0 0 9.06E+06 4.72E+06 - - - 3.0584 0.994 230117_WJC_METTL3_WT_vs_EV_F04.14697.14697.2 0.431 14-Jul K.IPGLVTLK[136.11].K "sp|Q9UK61|TASOR_HUMAN,tr|A0A087X0F1|A0A087X0F1_HUMAN" 2 847.5622 1.59 29985 14697 2 847.563035 424.7884 Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3 8.75 3122.2 - 583439 - - - 0.938 - 1.096 0.21 - 83.6 1 2 0 0.0008 8 0 0 0 1.86E+07 1.17E+07 - - - 0.8683 0.9954 230117_WJC_METTL3_WT_vs_EV_F04.14714.14714.2 0.0129 14-Aug K.LTPLLSVR.E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 897.5648 0.96 29994 14714 2 897.567975 449.7897 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3124.4 - 1.20E+06 - - - 3.5897 - 1.499 0.216 - 258.7 1 2 0 0.0032 8 0 0 0 2.11E+08 2.20E+08 - - - 1.8562 0.9651 230117_WJC_METTL3_WT_vs_EV_F04.14720.14720.2 4.17 12-Jun K.LVLILNK.S "sp|Q9BVP2|GNL3_HUMAN,sp|Q96RW7|HMCN1_HUMAN" 2 811.5531 0.95 29997 14720 2 811.554004 406.7838 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.75 3125.1 - 990077 - - - 1.0831 - 1.26 0.001 - 125.6 2 2 0 0.0009 7 0 0 0 5.09E+07 5.34E+07 - - - -0.3541 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.14722.14722.2 0.000848 12-Jul K.FDLMYAK.R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 886.4259 3.37 29999 14722 2 886.426583 444.2202 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3125.3 - 1.69E+06 - - - 0.7976 - 1.54 0.427 - 161.5 1 2 0 0.0007 7 0 0 0 7.19E+08 2.13E+08 - - - 3.5627 0.991 230117_WJC_METTL3_WT_vs_EV_F04.14726.14726.2 13 12-Aug K.IGIEIIK.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 784.5058 2.25 30002 14726 2 784.506213 393.2602 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3125.9 - 2.07E+06 - - - 0.4742 - 1.664 0.02 - 139.5 2 2 0 0.0004 7 0 0 0 5.11E+07 2.27E+07 - - - 0.6676 0.9838 230117_WJC_METTL3_WT_vs_EV_F04.14728.14728.2 1.61 14-Jul K.LTPLLSVR[166.11].E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 907.573 0.96 30004 14728 2 907.574258 454.7938 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3126.1 - 3.58E+06 - - - 1.3608 - 1.223 0.067 - 216.1 1 2 0 0.0012 8 0 0 0 2.11E+08 2.20E+08 - - - 0.1426 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.14734.14734.2 1.34 12-Aug K.LVLILNK[136.11].S "sp|Q9BVP2|GNL3_HUMAN,sp|Q96RW7|HMCN1_HUMAN" 2 819.5673 0.95 30008 14734 2 819.568314 410.7909 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.75 3126.7 - 1.85E+06 - - - 1.2067 - 1.562 0.118 - 239.2 1 2 0 0.001 7 0 0 0 5.09E+07 5.34E+07 - - - 1.3253 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.14746.14746.2 0.289 18-Aug R.VLLGEGVLTK[136.11].E "sp|Q96S99|PKHF1_HUMAN,sp|Q9H8W4|PKHF2_HUMAN,tr|K7ELB8|K7ELB8_HUMAN,tr|K7EIX0|K7EIX0_HUMAN" 4 1035.6419 0.8 30016 14746 2 1035.64189 518.8282 Pleckstrin homology domain-containing family F member 1 OS=Homo sapiens OX=9606 GN=PLEKHF1 PE=1 SV=3 5.97 3128.3 - 848559 - - - -0.055 - 1.677 0.347 - 159.7 1 2 0 -0.0001 10 0 0 0 2.94E+07 3.69E+07 - - - 3.047 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.14748.14748.2 0.00102 12-Jun K.FDLMYAK[136.11].R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 894.4401 3.37 30018 14748 2 894.441245 448.2273 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3128.4 - 4.64E+06 - - - 1.307 - 1.538 0.31 - 108.6 1 2 0 0.0012 7 0 0 0 7.18E+08 2.13E+08 - - - 2.6943 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.14751.14751.2 0.00588 16-Sep K.GFVTADMIR.E sp|Q9UHQ9|NB5R1_HUMAN 1 1008.5063 1.52 30021 14751 2 1008.508473 505.2604 NADH-cytochrome b5 reductase 1 OS=Homo sapiens OX=9606 GN=CYB5R1 PE=1 SV=1 5.84 3128.7 - 362166 - - - 2.2033 - 1.763 0.429 - 277.6 1 2 0 0.0022 9 0 0 0 1.14E+07 7.48E+06 - - - 3.8493 0.8724 230117_WJC_METTL3_WT_vs_EV_F04.14754.14754.2 0.568 14-Mar R.KPC[160.03]SDDYR.K "sp|Q2TAA8|TXIP1_HUMAN,tr|B4DXD0|B4DXD0_HUMAN,tr|H3BQ72|H3BQ72_HUMAN,tr|H3BNS9|H3BNS9_HUMAN" 4 1039.4393 999 30024 14754 2 1039.442787 520.7269 Translin-associated factor X-interacting protein 1 OS=Homo sapiens OX=9606 GN=TSNAXIP1 PE=1 SV=1 5.95 3129 - 242989 - - - 3.3605 - 0.782 0.205 - 21.4 15 2 0 0.0035 8 0 0 0 3.84E+06 0.00E+00 - - - -0.713 0.9958 230117_WJC_METTL3_WT_vs_EV_F04.14759.14759.2 0.614 14-May R.LVTDLLQR[166.11].E sp|Q70UQ0|IKIP_HUMAN 1 966.5738 6.74 30027 14759 2 966.575528 484.2942 Inhibitor of nuclear factor kappa-B kinase-interacting protein OS=Homo sapiens OX=9606 GN=IKBIP PE=1 SV=1 5.84 3129.6 - 428273 - - - 1.8385 - 1.269 0.19 - 66.6 1 2 0 0.0018 8 0 0 0 6.73E+07 9.99E+06 - - - 1.1623 0.9965 230117_WJC_METTL3_WT_vs_EV_F04.14766.14766.2 0.092 12-Jul R.FC[160.03]DVLLR.V "sp|Q9HBE1|PATZ1_HUMAN,tr|B1ARF3|B1ARF3_HUMAN" 2 921.4742 0.03 30032 14766 2 921.475304 461.7444 "POZ-, AT hook-, and zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=PATZ1 PE=1 SV=1" 5.83 3130.5 - 471037 - - - 1.1731 - 1.067 0.271 - 191.2 1 2 0 0.0011 7 0 0 0 1.58E+07 5.15E+08 - - - 1.2478 0.986 230117_WJC_METTL3_WT_vs_EV_F04.14778.14778.2 0.323 14-Aug R.LYELDGLR[166.11].E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 987.5265 2.91 30040 14778 2 987.527226 494.7705 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3131.9 - 214659 - - - 0.7696 - 1.472 0.011 - 167.2 1 2 0 0.0008 8 0 0 0 6.58E+08 2.26E+08 - - - 0.288 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.14793.14793.2 0.0383 12-Jun R.ELFVMAR.E "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QSA9|J3QSA9_HUMAN" 4 864.4528 5.03 30048 14793 2 864.4525 433.2337 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 6.1 3133.9 - 1.87E+06 - - - -0.2996 - 1.237 0.358 - 192.5 1 2 0 -0.0003 7 0 0 0 1.72E+08 3.41E+07 - - - 2.359 0.9774 230117_WJC_METTL3_WT_vs_EV_F04.14795.14795.2 1.66 12-May R.AVTIFIR[166.11].G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 828.5097 4.31 30049 14795 2 828.510457 415.2621 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3134.1 - 6.33E+06 - - - 0.9209 - 1.306 0.059 - 99.7 7 2 0 0.0008 7 0 0 0 2.36E+09 5.49E+08 - - - -0.0551 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.14806.14806.2 0.00184 16-Aug K.IPFASLASR.L sp|P35573|GDE_HUMAN 1 960.5393 0.25 30055 14806 2 960.540822 481.2769 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3135.6 - 937157 - - - 1.6199 - 1.572 0.359 - 171.1 1 2 0 0.0016 9 0 0 0 2.31E+07 9.36E+07 - - - 3.0008 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.14813.14813.2 0.00947 16-Oct R.VLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 11 1028.5866 999 30059 14813 2 1028.586108 515.3006 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3136.4 - 7.38E+06 - - - -0.488 - 2.022 0.443 - 376.4 1 2 0 -0.0005 9 0 0 0 1.84E+09 0.00E+00 - - - 4.3498 0.9812 230117_WJC_METTL3_WT_vs_EV_F04.14832.14832.2 0.161 12-May R.IVFQEFR[166.11].Q "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN" 2 947.5104 0.78 30066 14832 2 947.508977 474.7625 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3138.9 - 1.17E+06 - - - -1.525 - 1.184 0.189 - 80.5 1 2 0 -0.0014 7 0 0 0 1.77E+08 2.27E+08 - - - 0.9717 0.9944 230117_WJC_METTL3_WT_vs_EV_F04.14833.14833.2 0.0299 16-Aug K.LLSSLGGFK[136.11].L sp|Q92616|GCN1_HUMAN 1 928.5473 1.94 30067 14833 2 928.545696 465.2809 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.75 3139 - 451338 - - - -1.7468 - 1.377 0.294 - 114.5 1 2 0 -0.0016 9 0 0 0 1.15E+07 5.92E+06 - - - 2.1375 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.14836.14836.2 0.37 14-Sep R.LIEILSEK.A "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 943.559 2.39 30070 14836 2 943.558856 472.7868 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 3139.3 - 1.58E+06 - - - -0.1516 - 1.528 0.146 - 200.2 1 2 0 -0.0001 8 0 0 0 4.79E+07 2.00E+07 - - - 1.398 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.14856.14856.2 0.00169 18-Sep K.AYAALAALEK[136.11].L sp|Q12906|ILF3_HUMAN 1 1027.5793 0.35 30076 14856 2 1027.577063 514.7969 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.05 3142.3 - 1.17E+06 - - - -2.2227 - 1.704 0.422 - 200.7 1 2 0 -0.0023 10 0 0 0 3.05E+08 8.73E+08 - - - 3.6449 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.14859.14859.2 0.000128 14/22 K.FAQALGLTEAVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1246.6921 0.88 30077 14859 2 1246.690451 624.3533 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3142.6 - 810366 - - - -1.3532 - 2.485 0.396 - 701.3 1 2 0 -0.0017 12 0 0 0 2.66E+07 3.01E+07 - - - 4.3604 0.9742 230117_WJC_METTL3_WT_vs_EV_F04.14863.14863.2 0.376 12-Jul K.YLPDIIK.D sp|O15355|PPM1G_HUMAN 1 860.5008 4.05 30079 14863 2 860.497103 431.2577 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 5.83 3143.1 - 2.70E+06 - - - -4.244 - 1.339 0.296 - 152.2 1 2 0 -0.0037 7 0 0 0 1.79E+08 4.43E+07 - - - 2.1511 0.976 230117_WJC_METTL3_WT_vs_EV_F04.14869.14869.2 4.62 12-Jul K.LGFEEFK.Y "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 868.4331 2.53 30082 14869 2 868.432893 435.2238 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 3143.9 - 1.19E+06 - - - -0.2038 - 1.13 0.106 - 133.3 1 2 0 -0.0002 7 0 0 0 2.04E+08 8.05E+07 - - - 0.2111 0.992 230117_WJC_METTL3_WT_vs_EV_F04.14890.14890.2 0.0123 14-Jun K.LLFYATSR.A "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 969.5284 0.48 30089 14890 2 969.525342 485.7715 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 8.75 3146.7 - 1.02E+06 - - - -3.1201 - 1.4 0.353 - 126.5 1 2 0 -0.003 8 0 0 0 4.89E+07 1.02E+08 - - - 2.6621 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.14896.14896.2 0.00015 16-Sep R.AFSYYGPLR[166.11].T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1082.5425 0.89 30092 14896 2 1082.5405 542.2785 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3147.5 - 1.64E+06 - - - -1.8022 - 1.725 0.322 - 342.3 1 2 0 -0.002 9 0 0 0 2.51E+08 2.82E+08 - - - 2.9961 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.14897.14897.2 0.000108 16-Sep R.AFSYYGPLR.T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1072.5342 0.89 30093 14897 2 1072.532695 537.2744 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3147.6 - 1.21E+06 - - - -1.3855 - 1.579 0.488 - 293.5 1 2 0 -0.0015 9 0 0 0 2.51E+08 2.82E+08 - - - 3.9664 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.14902.14902.2 0.269 16-Sep R.ILDSAEFIK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1042.579 0.95 30094 14902 2 1042.579426 522.2968 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3148.3 - 1.60E+06 - - - 0.3971 - 1.792 0.228 - 160.7 1 2 0 0.0004 9 0 0 0 6.92E+09 7.26E+09 - - - 2.4125 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.14907.14907.2 0.000864 16-Sep R.ILDSAEFIK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1034.5648 0.95 30097 14907 2 1034.562878 518.2897 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3149 - 1.78E+06 - - - -1.8694 - 1.61 0.431 - 160.8 1 2 0 -0.0019 9 0 0 0 6.92E+09 7.26E+09 - - - 3.6015 0.9867 230117_WJC_METTL3_WT_vs_EV_F04.14919.14919.2 0.0955 12-Jun K.YNIMLVR.L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 907.495 8.41 30104 14919 2 907.491981 454.7548 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3150.4 - 380616 - - - -3.2805 - 1.448 0.272 - 156.8 1 2 0 -0.003 7 0 0 0 1.64E+09 1.95E+08 - - - 2.222 0.9944 230117_WJC_METTL3_WT_vs_EV_F04.14926.14926.2 0.00745 12-Jul K.YVLALVK[136.11].K "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 812.5251 1.12 30108 14926 2 812.523211 407.2698 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.59 3151.2 - 1.78E+06 - - - -2.3569 - 1.341 0.346 - 163.1 1 2 0 -0.0019 7 0 0 0 3.82E+07 3.41E+07 - - - 2.5257 0.9876 230117_WJC_METTL3_WT_vs_EV_F04.14934.14934.2 0.15 12-Jun K.YNIMLVR[166.11].L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 917.5032 8.4 30111 14934 2 917.501421 459.7589 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3152.3 - 2.29E+06 - - - -1.9695 - 1.318 0.219 - 150.9 1 2 0 -0.0018 7 0 0 0 1.64E+09 1.95E+08 - - - 1.5329 0.8636 230117_WJC_METTL3_WT_vs_EV_F04.14935.14935.2 4.76 12-Apr R.VDDFLR[166.11]R.T "sp|Q96MU7|YTDC1_HUMAN,tr|J3QR07|J3QR07_HUMAN" 2 929.4958 - 30112 14935 2 929.495582 465.7552 YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3 5.93 3152.4 - 1.03E+06 - - - -0.2722 - 1.093 0.012 - 55.7 6 2 0 -0.0003 7 0 0 0 - - - - - -0.9363 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.14939.14939.2 0.00148 20-Nov K.LVLLGESAVGK[136.11].S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1092.6634 1.43 30114 14939 2 1092.662295 547.339 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3152.9 - 844081 - - - -1.0214 - 2.225 0.382 - 266.2 1 2 0 -0.0011 11 0 0 0 1.16E+08 8.11E+07 - - - 4.0256 0.997 230117_WJC_METTL3_WT_vs_EV_F04.14942.14942.2 0.173 16-Jun R.LEPLYSPIR[166.11].S sp|Q9UBB9|TFP11_HUMAN 1 1096.6156 1.35 30116 14942 2 1096.616411 549.3151 Tuftelin-interacting protein 11 OS=Homo sapiens OX=9606 GN=TFIP11 PE=1 SV=1 6 3153.3 - 639323 - - - 0.725 - 1.154 0.271 - 73.1 1 2 0 0.0008 9 0 0 0 2.43E+07 1.80E+07 - - - 1.4567 0.9814 230117_WJC_METTL3_WT_vs_EV_F04.14952.14952.2 0.496 12-Aug R.LNLYELK.E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 891.5066 2.05 30121 14952 2 891.505396 446.7606 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3154.6 - 1.60E+06 - - - -1.3158 - 1.389 0.108 - 193.1 1 2 0 -0.0012 7 0 0 0 1.97E+08 9.62E+07 - - - 0.8795 0.9717 230117_WJC_METTL3_WT_vs_EV_F04.14956.14956.2 0.294 12-Aug R.LNLYELK[136.11].E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 899.5208 2.02 30123 14956 2 899.518001 450.7677 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3155.1 - 2.46E+06 - - - -3.0772 - 1.628 0.112 - 193.1 1 2 0 -0.0028 7 0 0 0 1.97E+08 9.75E+07 - - - 1.4116 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.14968.14968.2 0.00822 16-Aug K.YLPELMAEK[136.11].D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1100.5667 1.15 30127 14968 2 1100.567457 551.2906 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3156.8 - 1.07E+06 - - - 0.6578 - 1.294 0.309 - 201 1 2 0 0.0007 9 0 0 0 1.06E+08 9.21E+07 - - - 2.0687 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.14971.14971.2 0.00442 20-Oct K.LVLLGESAVGK.S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1084.6492 1.43 30128 14971 2 1084.6489 543.3319 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3157.2 - 2.36E+06 - - - -0.2867 - 1.999 0.252 - 252.5 1 2 0 -0.0003 11 0 0 0 1.16E+08 8.11E+07 - - - 2.7759 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.14973.14973.2 0.0562 16-Aug K.YLPELMAEK.D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1092.5525 1.15 30130 14973 2 1092.553057 547.2835 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3157.4 - 1.26E+06 - - - 0.4796 - 1.277 0.36 - 174.2 1 2 0 0.0005 9 0 0 0 1.06E+08 9.22E+07 - - - 2.4072 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.14983.14983.2 0.0154 12-Jul K.FADFMVK.D "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 14 856.4153 1.62 30135 14983 2 856.416451 429.2149 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 5.84 3158.7 - 500925 - - - 1.3311 - 1.466 0.374 - 120.5 1 2 0 0.0011 7 0 0 0 2.80E+07 1.73E+07 - - - 3.0151 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.14994.14994.2 0.677 12-Aug K.LILEYVK.A "sp|Q7L5N1|CSN6_HUMAN,tr|E7EM64|E7EM64_HUMAN" 2 876.5321 2.83 30141 14994 2 876.532591 439.2733 COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1 6 3160.1 - 2.34E+06 - - - 0.6115 - 1.625 0.202 - 171.2 1 2 0 0.0005 7 0 0 0 3.27E+07 1.15E+07 - - - 2.0712 1 230117_WJC_METTL3_WT_vs_EV_F04.14997.14997.2 5.38E-08 15/26 R.VPTANVSVVDLTC[160.03]R.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1529.7872 28.39 30142 14997 2 1529.786178 765.9009 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3160.5 - 0 - - - -0.6537 - 2.711 0.591 - 380.2 1 2 0 -0.001 14 0 0 0 6.99E+06 2.46E+05 - - - 5.9085 0.9958 230117_WJC_METTL3_WT_vs_EV_F04.15006.15006.2 0.0866 14-Aug R.VMLYPSRI.- sp|P18077|RL35A_HUMAN 1 977.5368 0.71 30147 15006 2 977.535287 489.7757 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.72 3161.5 - 1.68E+06 - - - -1.5713 - 1.461 0.289 - 343.9 1 2 0 -0.0015 8 0 0 0 5.86E+07 8.25E+07 - - - 2.3185 0.998 230117_WJC_METTL3_WT_vs_EV_F04.15014.15014.2 0.0893 14-May R.VMLYPSR[166.11]I.- sp|P18077|RL35A_HUMAN 1 987.5451 0.74 30153 15014 2 987.544982 494.7798 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.72 3162.4 - 2.16E+06 - - - -0.1124 - 1.383 0.285 - 125.6 1 2 0 -0.0001 8 0 0 0 6.09E+07 8.25E+07 - - - 2.1239 0.9893 230117_WJC_METTL3_WT_vs_EV_F04.15020.15020.2 0.347 14-May K.IEPPGLFR[166.11].G "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|E5RJ95|E5RJ95_HUMAN,tr|E5RIC7|E5RIC7_HUMAN,tr|E5RFS0|E5RFS0_HUMAN" 5 937.5261 0.7 30158 15020 2 937.525435 469.7703 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 6 3162.9 - 5.57E+06 - - - -0.6794 - 1.098 0.226 - 103 1 2 0 -0.0006 8 0 0 0 7.16E+07 1.02E+08 - - - 0.992 0.9785 230117_WJC_METTL3_WT_vs_EV_F04.15022.15022.2 0.349 12-May K.WDPVVLK.N sp|Q9BVJ6|UT14A_HUMAN 1 855.4854 1.26 30160 15022 2 855.484544 428.75 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 5.84 3163 - 3.21E+06 - - - -1.0474 - 0.851 0.287 - 98 1 2 0 -0.0009 7 0 0 0 5.21E+07 4.15E+07 - - - 0.6493 0.9957 230117_WJC_METTL3_WT_vs_EV_F04.15023.15023.2 0.0376 12-Aug K.WDPVVLK[136.11].N sp|Q9BVJ6|UT14A_HUMAN 1 863.4996 1.26 30161 15023 2 863.498811 432.7571 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 5.84 3163.1 - 2.25E+06 - - - -0.96 - 1.244 0.295 - 161.8 1 2 0 -0.0008 7 0 0 0 5.25E+07 4.18E+07 - - - 1.9114 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.15028.15028.2 0.0108 13/20 R.MGAGMGFGLER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1134.519 2.11 30164 15028 2 1134.518771 568.2668 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 3163.7 - 609384 - - - -0.1622 - 2.068 0.42 - 374.1 1 2 0 -0.0002 11 0 0 0 3.61E+07 1.71E+07 - - - 4.1086 0.9928 230117_WJC_METTL3_WT_vs_EV_F04.15036.15036.2 0.76 12-Jun R.DLGAYLR.Q "sp|Q9BRT2|UQCC2_HUMAN,tr|Q5TAQ0|Q5TAQ0_HUMAN,tr|V5IRT4|V5IRT4_HUMAN" 3 806.4287 0.27 30170 15036 2 806.429098 404.2216 Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1 5.84 3164.7 - 806822 - - - 0.5518 - 1.318 0.12 - 126 1 2 0 0.0004 7 0 0 0 6.75E+06 2.50E+07 - - - 0.8021 0.9505 230117_WJC_METTL3_WT_vs_EV_F04.15037.15037.2 1.05 14-Jul K.LMALGPIR.L "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 869.5157 33.4 30171 15037 2 869.513235 435.7651 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 9.75 3164.8 - 514748 - - - -2.828 - 1.385 0.111 - 96.2 1 2 0 -0.0025 8 0 0 0 1.01E+07 3.02E+05 - - - 0.8424 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.15041.15041.2 0.18 14-Aug K.LIYLVPEK.Q "sp|Q9NZM3|ITSN2_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN,tr|E7EPJ2|E7EPJ2_HUMAN" 3 973.5848 3.8 30173 15041 2 973.58561 487.7997 Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3 6 3165.4 - 1.03E+06 - - - 0.8125 - 1.346 0.193 - 180.6 1 2 0 0.0008 8 0 0 0 2.38E+07 6.27E+06 - - - 1.3624 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.15042.15042.2 0.00364 14-Sep R.LLEIVSYK.L "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 963.5641 1.1 30174 15042 2 963.564745 482.7893 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6 3165.5 - 179494 - - - 0.686 - 1.803 0.405 - 230.7 1 2 0 0.0007 8 0 0 0 6.23E+07 5.68E+07 - - - 3.8099 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.15059.15059.2 0.0904 14-Sep R.VGEIVVFR[166.11].L "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 927.5417 2.37 30187 15059 2 927.54534 464.7781 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.97 3167.5 - 2.38E+06 - - - 3.9006 - 1.597 0.35 - 310.1 1 2 0 0.0036 8 0 0 0 4.07E+07 1.72E+07 - - - 3.0368 0.99 230117_WJC_METTL3_WT_vs_EV_F04.15062.15062.2 0.356 12-Jul K.WTNLLYK[136.11].A sp|O75683|SURF6_HUMAN 1 944.5211 1.41 30190 15062 2 944.522167 473.2678 Surfeit locus protein 6 OS=Homo sapiens OX=9606 GN=SURF6 PE=1 SV=3 8.59 3167.9 - 917759 - - - 1.1265 - 1.212 0.112 - 113.9 1 2 0 0.0011 7 0 0 0 1.11E+07 7.89E+06 - - - 0.4771 0.9846 230117_WJC_METTL3_WT_vs_EV_F04.15063.15063.3 0.000499 13/44 R.YLYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1484.8126 0.1 30191 15063 3 1484.814843 495.9448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3168 - 442395 - - - 1.479 - 1.861 0.391 - 154.3 1 2 1 0.0022 12 0 0 0 5.73E+06 5.62E+07 - - - 4.6203 1 230117_WJC_METTL3_WT_vs_EV_F04.15064.15064.2 0.000135 28-Dec R.NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1656.8459 2.9 30192 15064 2 1656.849993 829.4302 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3168.1 - 412152 - - - 2.4685 - 2.472 0.513 - 306.8 1 2 0 0.0041 15 0 0 0 1.27E+07 4.40E+06 - - - 5.0538 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.15069.15069.2 0.00251 14-Sep R.VGEIVVFR.L "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 917.5335 2.34 30195 15069 2 917.533785 459.774 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.97 3168.8 - 2.61E+06 - - - 0.3629 - 2.039 0.375 - 307.9 1 2 0 0.0003 8 0 0 0 4.10E+07 1.75E+07 - - - 3.9594 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.15074.15074.2 0.586 14-Oct K.GAIEVLIR[166.11].E "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 879.5417 1.17 30200 15074 2 879.543643 440.7781 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 6 3169.4 - 1.02E+06 - - - 2.1841 - 2.073 0.17 - 267 1 2 0 0.0019 8 0 0 0 3.60E+07 3.09E+07 - - - 2.4946 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.15075.15075.2 0.0117 16-Sep K.ANPALYVLR[166.11].E sp|Q6P2Q9|PRP8_HUMAN 1 1025.5897 1.38 30201 15075 2 1025.592212 513.8021 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.79 3169.5 - 978296 - - - 2.4152 - 1.593 0.329 - 262.7 1 2 0 0.0025 9 0 0 0 7.80E+07 5.66E+07 - - - 2.8173 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.15079.15079.2 3.58E-06 14/28 R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 0.98 30205 15079 2 1646.833724 824.4261 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3170 - 396203 - - - -2.3736 - 2.43 0.434 - 503.1 1 2 0 -0.0039 15 0 0 0 3.43E+06 3.51E+06 - - - 4.4282 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.15084.15084.2 4.19 12-Jul R.LIVDVIR.F "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 826.5276 1.13 30208 15084 2 826.528243 414.2711 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.84 3170.6 - 1.51E+06 - - - 0.7308 - 1.548 0.157 - 164.4 1 2 0 0.0006 7 0 0 0 5.88E+07 5.19E+07 - - - 1.585 0.9054 230117_WJC_METTL3_WT_vs_EV_F04.15095.15095.2 0.176 12-Jul K.LYGFPYK[136.11].L "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 894.4731 1.14 30217 15095 2 894.469158 448.2438 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 8.5 3171.8 - 260028 - - - -4.3959 - 1.253 0.176 - 118.9 1 2 0 -0.0039 7 0 0 0 2.55E+07 2.25E+07 - - - 1.0543 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.15096.15096.2 0.0518 14-Jun K.FLVGFTNK[136.11].G "sp|P43307|SSRA_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|C9J5W0|C9J5W0_HUMAN" 6 932.5211 1.42 30218 15096 2 932.52317 467.2678 Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3 8.75 3171.9 - 1.55E+06 - - - 2.2166 - 1.472 0.423 - 98.3 1 2 0 0.0021 8 0 0 0 2.20E+08 1.55E+08 - - - 3.3307 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.15097.15097.2 0.000152 16-Sep R.AFGYYGPLR[166.11].S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1052.5319 1.06 30219 15097 2 1052.533631 527.2732 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3172.1 - 927246 - - - 1.6579 - 1.773 0.443 - 323.3 1 2 0 0.0017 9 0 0 0 1.32E+09 1.25E+09 - - - 3.9692 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.15098.15098.2 0.077 16-Sep K.MLLYTEVTR[166.11].Y "sp|P31150|GDIA_HUMAN,sp|P50395|GDIB_HUMAN,tr|G5E9U5|G5E9U5_HUMAN,tr|Q5SX86|Q5SX86_HUMAN,tr|Q5SX90|Q5SX90_HUMAN,tr|V9GYF8|V9GYF8_HUMAN,tr|V9GYJ7|V9GYJ7_HUMAN" 7 1134.5983 1.32 30220 15098 2 1134.600356 568.3064 Rab GDP dissociation inhibitor alpha OS=Homo sapiens OX=9606 GN=GDI1 PE=1 SV=2 5.75 3172.2 - 316311 - - - 1.8553 - 1.56 0.301 - 337.8 1 2 0 0.0021 9 0 0 0 1.76E+07 1.33E+07 - - - 2.55 0.9849 230117_WJC_METTL3_WT_vs_EV_F04.15099.15099.2 1.77 16-Jul R.LLLPTPTVK[136.11].Q "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 988.6412 2.43 30221 15099 2 988.643278 495.3279 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 3172.3 - 198955 - - - 2.0837 - 1.113 0.126 - 102.1 1 2 0 0.0021 9 0 0 0 4.38E+08 1.80E+08 - - - 0.2807 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.15105.15105.2 0.000179 16-Sep R.AFGYYGPLR.S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1042.5236 1 30225 15105 2 1042.525288 522.2691 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3173.1 - 2.35E+06 - - - 1.6038 - 1.858 0.436 - 326.8 1 2 0 0.0017 9 0 0 0 1.24E+09 1.24E+09 - - - 4.053 0.9942 230117_WJC_METTL3_WT_vs_EV_F04.15108.15108.2 1.71 14-Jul K.LLIESLEK.Y "sp|Q8TC07|TBC15_HUMAN,tr|F8VV61|F8VV61_HUMAN,tr|C9JA93|C9JA93_HUMAN" 3 943.559 2.31 30228 15108 2 943.561166 472.7868 TBC1 domain family member 15 OS=Homo sapiens OX=9606 GN=TBC1D15 PE=1 SV=2 4.53 3173.4 - 2.31E+06 - - - 2.2966 - 1.456 0.115 - 112.5 1 2 0 0.0022 8 0 0 0 2.37E+07 1.03E+07 - - - 1.0228 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.15110.15110.2 0.146 16-Oct R.LLLPTPTVK.Q "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 980.627 2.43 30230 15110 2 980.62835 491.3208 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 3173.6 - 1.54E+06 - - - 1.3583 - 1.62 0.217 - 301.6 1 2 0 0.0013 9 0 0 0 4.38E+08 1.80E+08 - - - 2.039 0.9949 230117_WJC_METTL3_WT_vs_EV_F04.15124.15124.2 0.158 12-Jul R.QMSLLLR.R sp|P25705|ATPA_HUMAN 1 859.495 1.53 30240 15124 2 859.495749 430.7548 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 9.75 3175.3 - 2.51E+06 - - - 0.9203 - 1.427 0.111 - 285.2 1 2 0 0.0008 7 0 0 0 2.13E+08 1.39E+08 - - - 0.9873 1 230117_WJC_METTL3_WT_vs_EV_F04.15127.15127.2 0.0388 20-Dec R.VFSGLVSTGLK.V sp|P13639|EF2_HUMAN 1 1106.6336 3.17 30243 15127 2 1106.634303 554.3241 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.72 3175.7 - 306253 - - - 0.6714 - 2.128 0.487 - 412.6 1 2 0 0.0007 11 0 0 0 8.41E+07 2.66E+07 - - - 4.6807 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.15133.15133.2 0.0023 14-May K.NVPYVFVR.S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 992.5444 1.16 30248 15133 2 992.545498 497.2795 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3176.1 - 663639 - - - 1.1556 - 1.157 0.429 - 104.9 1 2 0 0.0011 8 0 0 0 2.94E+08 2.53E+08 - - - 2.6491 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.15142.15142.2 0.000106 13/20 R.IALTDNALIAR[166.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1179.6851 0.77 30252 15142 2 1179.685337 590.8498 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3177.3 - 164528 - - - 0.2077 - 2.198 0.373 - 499.7 1 2 0 0.0002 11 0 0 0 2.34E+07 3.02E+07 - - - 3.9264 1 230117_WJC_METTL3_WT_vs_EV_F04.15147.15147.2 5.35E-06 16-Nov K.YMAC[160.03]C[160.03]LLYR.G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1248.5454 3.14 30254 15147 2 1248.544909 625.28 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3177.9 - 1.31E+06 - - - -0.358 - 1.962 0.616 - 480.1 1 2 0 -0.0004 9 0 0 0 2.15E+08 6.86E+07 - - - 5.5405 0.9947 230117_WJC_METTL3_WT_vs_EV_F04.15155.15155.2 1.4 12-Jun K.EILFYDR[166.11].L sp|Q08J23|NSUN2_HUMAN 1 964.4894 1.71 30258 15155 2 964.490001 483.252 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.37 3178.9 - 616789 - - - 0.6729 - 1.321 0.147 - 137.2 1 2 0 0.0006 7 0 0 0 1.05E+08 6.15E+07 - - - 1.0086 0.9844 230117_WJC_METTL3_WT_vs_EV_F04.15156.15156.2 3.11 12-Jul K.NLILVVR.G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 825.5436 1.14 30259 15156 2 825.543826 413.7791 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3178.9 - 1.53E+06 - - - 0.2459 - 1.418 0.027 - 184.2 1 2 0 0.0002 7 0 0 0 1.74E+08 1.53E+08 - - - 0.347 1 230117_WJC_METTL3_WT_vs_EV_F04.15157.15157.2 1.20E-05 16-Oct K.YMAC[160.03]C[160.03]LLYR[166.11].G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1258.5536 3.14 30260 15157 2 1258.555831 630.2841 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3179.1 - 505289 - - - 1.752 - 1.822 0.608 - 346.6 1 2 0 0.0022 9 0 0 0 2.15E+08 6.86E+07 - - - 5.2666 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.15161.15161.2 0.0144 20-Aug R.IALTDNALIAR.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1169.6768 0.77 30262 15161 2 1169.677621 585.8457 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3179.6 - 556579 - - - 0.6831 - 1.898 0.281 - 132 1 2 0 0.0008 11 0 0 0 2.34E+07 3.02E+07 - - - 2.8497 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.15169.15169.2 0.0353 12-Jun K.EILFYDR.L sp|Q08J23|NSUN2_HUMAN 1 954.4811 1.71 30266 15169 2 954.481417 478.2478 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.37 3180.6 - 1.64E+06 - - - 0.351 - 1.381 0.333 - 176.9 1 2 0 0.0003 7 0 0 0 1.05E+08 6.15E+07 - - - 2.5233 0.9756 230117_WJC_METTL3_WT_vs_EV_F04.15174.15174.2 2.21 12-Jul K.NLILVVR[166.11].G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 835.5519 1.14 30269 15174 2 835.551559 418.7832 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3181.1 - 7.36E+06 - - - -0.3997 - 1.184 0.095 - 277.1 1 2 0 -0.0003 7 0 0 0 1.74E+08 1.53E+08 - - - 0.2777 0.9559 230117_WJC_METTL3_WT_vs_EV_F04.15188.15188.2 3.09 14-Jul K.VLAC[160.03]PFLR.E sp|Q709C8|VP13C_HUMAN 1 974.5372 0.13 30274 15188 2 974.536077 488.2759 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 8.22 3183 - 1.09E+06 - - - -1.1092 - 1.258 0.059 - 75.8 1 2 0 -0.0011 8 0 0 0 2.23E+07 1.70E+08 - - - 0.1687 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.15190.15190.2 0.0652 14-Jun K.LIINSLYK.N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 962.5801 0.93 30275 15190 2 962.579539 482.2973 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3183.2 - 2.04E+06 - - - -0.5496 - 1.14 0.308 - 70.6 1 2 0 -0.0005 8 0 0 0 1.72E+08 1.85E+08 - - - 1.7109 0.999 230117_WJC_METTL3_WT_vs_EV_F04.15197.15197.2 0.033 12-Jul R.FLTVMMK[136.11].H "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 876.4693 1.28 30280 15197 2 876.469493 439.2419 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.75 3184 - 3.25E+06 - - - 0.2579 - 1.412 0.336 - 149 1 2 0 0.0002 7 0 0 0 2.14E+08 1.67E+08 - - - 2.6158 0.9685 230117_WJC_METTL3_WT_vs_EV_F04.15198.15198.2 3.47 12-Jul R.FLTVMMK.H "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 868.4551 1.29 30281 15198 2 868.454194 435.2348 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.75 3184 - 4.08E+06 - - - -1.0052 - 1.234 0.088 - 164.8 1 2 0 -0.0009 7 0 0 0 2.15E+08 1.67E+08 - - - 0.3569 0.985 230117_WJC_METTL3_WT_vs_EV_F04.15207.15207.2 0.654 12-Jun R.LYIWSGR[166.11].D "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 903.4842 1.88 30287 15207 2 903.48341 452.7494 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 8.75 3185 - 329839 - - - -0.8832 - 1.175 0.174 - 121.7 1 2 0 -0.0008 7 0 0 0 6.70E+07 3.56E+07 - - - 0.8369 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.15211.15211.2 0.0132 16-Sep R.LPEAAFLAR.T "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 986.5549 2.75 30288 15211 2 986.553898 494.2847 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 6 3185.6 - 2.56E+06 - - - -1.0319 - 1.596 0.285 - 285 1 2 0 -0.001 9 0 0 0 1.99E+08 7.26E+07 - - - 2.4982 0.998 230117_WJC_METTL3_WT_vs_EV_F04.15228.15228.2 0.0224 14-Jul K.LIINSLYK[136.11].N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 970.5943 0.93 30300 15228 2 970.593934 486.3044 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3187.6 - 2.69E+06 - - - -0.3441 - 1.323 0.326 - 107.5 1 2 0 -0.0003 8 0 0 0 1.72E+08 1.85E+08 - - - 2.2929 0.9927 230117_WJC_METTL3_WT_vs_EV_F04.15229.15229.2 0.162 12-Jun K.LVFDGLR[166.11].K sp|P15924|DESP_HUMAN 1 828.4733 35.61 30301 15229 2 828.472412 415.2439 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.84 3187.7 - 856233 - - - -1.0815 - 1.201 0.255 - 116.8 1 2 0 -0.0009 7 0 0 0 1.56E+09 4.38E+07 - - - 1.5045 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.15236.15236.2 0.000761 18-Sep R.LVQAFQFTDK.H "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 3 1195.6237 5.98 30304 15236 2 1195.623845 598.8191 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.84 3188.6 - 512436 - - - 0.1012 - 1.684 0.373 - 191.8 1 2 0 0.0001 10 0 0 0 6.59E+06 1.10E+06 - - - 3.2507 0.999 230117_WJC_METTL3_WT_vs_EV_F04.15241.15241.2 0.019 16-Nov R.LPEAAFLAR[166.11].T "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 996.5632 2.75 30307 15241 2 996.563285 499.2889 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 6 3189.1 - 2.33E+06 - - - 0.0993 - 1.79 0.277 - 446.3 1 2 0 0.0001 9 0 0 0 1.99E+08 7.25E+07 - - - 2.7713 0.9623 230117_WJC_METTL3_WT_vs_EV_F04.15243.15243.2 0.0347 16-Apr K.DDAGLPPPK.A sp|O43909|EXTL3_HUMAN 1 908.4603 2.09 30309 15243 2 908.464562 455.2374 Exostosin-like 3 OS=Homo sapiens OX=9606 GN=EXTL3 PE=1 SV=1 4.21 3189.4 - 1.20E+06 - - - 4.6397 - 1.131 0.233 - 37.7 8 2 0 0.0042 9 0 0 0 3.41E+07 1.63E+07 - - - 0.7133 0.9972 230117_WJC_METTL3_WT_vs_EV_F04.15259.15259.2 0.0018 22-Sep K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.03 30317 15259 2 1277.747757 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3191.3 - 204621 - - - -1.4369 - 1.749 0.293 - 195.3 1 2 0 -0.0018 12 0 0 0 8.08E+06 7.85E+06 - - - 2.6755 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.15262.15262.2 0.329 18-Oct K.IVLLSANSIR.A "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 1084.6604 2.06 30318 15262 2 1084.661209 543.3375 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 9.75 3191.7 - 2.08E+06 - - - 0.7053 - 1.542 0.251 - 291.1 1 2 0 0.0008 10 0 0 0 3.83E+07 1.86E+07 - - - 2.1035 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.15263.15263.2 0.00224 16-Sep R.LLVHMGLLK.S sp|P46060|RAGP1_HUMAN 1 1022.6311 1.87 30319 15263 2 1022.631797 512.3228 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 8.76 3191.9 - 465898 - - - 0.7226 - 1.842 0.401 - 187.5 1 2 0 0.0007 9 0 0 0 7.55E+06 4.04E+06 - - - 3.7698 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.15269.15269.2 0.0298 22-Aug K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.11 30322 15269 2 1287.761367 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3192.7 - 282202 - - - 2.721 - 1.723 0.296 - 139.8 1 2 0 0.0035 12 0 0 0 8.39E+06 7.55E+06 - - - 2.6577 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.15270.15270.2 3.95E-06 14/22 K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 999 30323 15270 2 1356.689813 679.3515 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3192.8 - 737823 - - - 0.9612 - 2.85 0.355 - 870.4 1 2 0 0.0013 12 0 0 0 1.87E+07 0.00E+00 - - - 4.4183 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.15284.15284.2 0.00336 20-Nov R.AVAQALEVIPR.T "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1165.6819 999 30332 15284 2 1165.686004 583.8482 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.05 3194.7 - 146916 - - - 3.5138 - 2.354 0.401 - 395.9 1 2 0 0.0041 11 0 0 0 2.79E+06 0.00E+00 - - - 4.3175 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.15289.15289.2 0.0816 16-May R.YLYLSTMER.S "sp|Q10570|CPSF1_HUMAN,tr|A0A087X101|A0A087X101_HUMAN" 2 1174.5692 0.84 30336 15289 2 1174.57161 588.2919 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6 3195.3 - 172014 - - - 2.0127 - 1.223 0.33 - 79.8 1 2 0 0.0024 9 0 0 0 3.54E+06 4.21E+06 - - - 2.06 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.15298.15298.2 0.219 14-Aug R.LLLNYAVR.L "sp|Q92989|CLP1_HUMAN,tr|E9PL17|E9PL17_HUMAN,tr|E9PKV5|E9PKV5_HUMAN" 3 960.5757 0.99 30341 15298 2 960.577902 481.2951 Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1 8.75 3196.5 - 280696 - - - 2.3423 - 1.576 0.162 - 174.4 1 2 0 0.0022 8 0 0 0 1.52E+08 1.54E+08 - - - 1.6088 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.15303.15303.2 0.0177 12-Jul R.WFVTC[160.03]VR.Q "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN,tr|A0A140T954|A0A140T954_HUMAN" 3 966.4746 0.68 30346 15303 2 966.477255 484.2446 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 8.25 3197.2 - 272250 - - - 2.7906 - 1.241 0.317 - 135.9 1 2 0 0.0027 7 0 0 0 6.77E+06 9.95E+06 - - - 2.0657 0.9759 230117_WJC_METTL3_WT_vs_EV_F04.15307.15307.2 0.0011 16-Dec R.PAVLSGYFK.Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 980.5331 1.04 30348 15307 2 980.535228 491.2738 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.01 3197.7 - 1.06E+06 - - - 2.1519 - 2.215 0.419 - 560.5 1 1 0 0.0021 9 0 0 0 1.22E+08 1.18E+08 - - - 4.4358 0.9909 230117_WJC_METTL3_WT_vs_EV_F04.15308.15308.2 0.694 12-Jun K.FLLLQQK[136.11].Y "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 896.5575 2.05 30349 15308 2 896.558012 449.286 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 8.75 3197.8 - 632216 - - - 0.5833 - 1.208 0.152 - 92.2 2 2 0 0.0005 7 0 0 0 5.11E+07 2.49E+07 - - - 0.6278 1 230117_WJC_METTL3_WT_vs_EV_F04.15310.15310.2 9.33E-07 18-Oct R.LITLEEEMTK.Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1205.6213 2.74 30351 15310 2 1205.62541 603.8179 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3198.1 - 147810 - - - 3.375 - 1.959 0.508 - 263 1 2 0 0.0041 10 0 0 0 2.21E+07 8.07E+06 - - - 4.6688 0.9962 230117_WJC_METTL3_WT_vs_EV_F04.15313.15313.2 0.512 12-Sep R.WGGLDLR[166.11].R sp|Q9H7N4|SFR19_HUMAN 1 825.4373 0.86 30352 15313 2 825.438001 413.7259 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.84 3198.5 - 2.39E+06 - - - 0.9013 - 1.347 0.166 - 282.4 1 2 0 0.0007 7 0 0 0 3.99E+07 4.62E+07 - - - 1.2107 0.9919 230117_WJC_METTL3_WT_vs_EV_F04.15316.15316.2 0.254 14-Aug K.LGFESIYK.L "sp|P49643|PRI2_HUMAN,tr|A0A5F9ZHU7|A0A5F9ZHU7_HUMAN" 2 955.5015 2.11 30355 15316 2 955.50485 478.758 DNA primase large subunit OS=Homo sapiens OX=9606 GN=PRIM2 PE=1 SV=2 6 3198.8 - 550070 - - - 3.5228 - 1.474 0.151 - 131.3 1 2 0 0.0034 8 0 0 0 1.64E+07 7.78E+06 - - - 1.3254 0.9648 230117_WJC_METTL3_WT_vs_EV_F04.15320.15320.2 1.11 12-Jul R.IYLYLTK[136.11].V "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 920.5463 1.77 30358 15320 2 920.549177 461.2804 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.5 3199.3 - 530333 - - - 3.1742 - 1.351 0.013 - 185.5 1 2 0 0.0029 7 0 0 0 5.44E+07 3.08E+07 - - - 0.0893 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.15322.15322.2 0.209 12-Jul R.WGGLDLR.R sp|Q9H7N4|SFR19_HUMAN 1 815.429 0.82 30359 15322 2 815.429857 408.7218 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.84 3199.5 - 1.68E+06 - - - 1.0669 - 1.349 0.202 - 232.7 1 2 0 0.0009 7 0 0 0 4.08E+07 5.00E+07 - - - 1.4812 0.9489 230117_WJC_METTL3_WT_vs_EV_F04.15324.15324.2 3.58 12-Jun K.LQQLWLK.A "sp|Q9NPC8|SIX2_HUMAN,sp|Q15475|SIX1_HUMAN" 2 927.5542 1.96 30361 15324 2 927.556986 464.7844 Homeobox protein SIX2 OS=Homo sapiens OX=9606 GN=SIX2 PE=1 SV=1 8.75 3199.8 - 644687 - - - 3.0165 - 1.163 0.053 - 80.6 2 2 0 0.0028 7 0 0 0 1.96E+07 1.00E+07 - - - -0.2244 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.15325.15325.2 0.182 18-Sep K.LVIIEGDLER.T "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1155.6499 1.29 30362 15325 2 1155.652917 578.8322 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.14 3199.9 - 460707 - - - 2.5769 - 1.669 0.263 - 264.6 1 2 0 0.003 10 0 0 0 2.21E+07 1.72E+07 - - - 2.4124 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.15327.15327.2 0.357 16-Jul R.ALVQSLLAK.E sp|Q9NX46|ADPRS_HUMAN 1 941.591 3.16 30364 15327 2 941.593691 471.8028 ADP-ribose glycohydrolase ARH3 OS=Homo sapiens OX=9606 GN=ADPRS PE=1 SV=1 8.8 3200.1 - 286013 - - - 2.893 - 1.434 0.28 - 107.9 1 2 0 0.0027 9 0 0 0 1.11E+07 3.53E+06 - - - 2.1511 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.15330.15330.2 0.0625 12-Jul K.SEFVILR.D "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 862.4913 0.98 30365 15330 2 862.49282 432.2529 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 5.72 3200.6 - 1.14E+06 - - - 1.8168 - 1.54 0.16 - 279.4 1 2 0 0.0016 7 0 0 0 4.58E+07 4.67E+07 - - - 1.5904 0.999 230117_WJC_METTL3_WT_vs_EV_F04.15333.15333.2 0.184 18-Sep K.LVIIEGDLER[166.11].T "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1165.6582 1.3 30368 15333 2 1165.658757 583.8364 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.14 3200.9 - 452681 - - - 0.4701 - 1.86 0.25 - 284.9 1 2 0 0.0005 10 0 0 0 2.21E+07 1.71E+07 - - - 2.6195 0.9486 230117_WJC_METTL3_WT_vs_EV_F04.15345.15345.2 2.55 14-Jun K.LGFESIYK[136.11].L "sp|P49643|PRI2_HUMAN,tr|A0A5F9ZHU7|A0A5F9ZHU7_HUMAN" 2 963.5157 4.64 30376 15345 2 963.517755 482.7651 DNA primase large subunit OS=Homo sapiens OX=9606 GN=PRIM2 PE=1 SV=2 6 3202.4 - 454660 - - - 2.1494 - 0.988 0.065 - 60.9 1 2 0 0.0021 8 0 0 0 3.63E+07 7.83E+06 - - - -0.516 0.9906 230117_WJC_METTL3_WT_vs_EV_F04.15348.15348.2 0.289 12-Jul R.LIMQYLK[136.11].E sp|Q2TAY7|SMU1_HUMAN 1 915.5343 0.93 30377 15348 2 915.53587 458.7744 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.59 3202.8 - 1.31E+06 - - - 1.7028 - 1.197 0.125 - 135.2 1 2 0 0.0016 7 0 0 0 4.30E+07 4.64E+07 - - - 0.5335 1 230117_WJC_METTL3_WT_vs_EV_F04.15354.15354.2 0.000211 16-Oct K.LGEWVGLC[160.03]K.L sp|P25398|RS12_HUMAN 1 1060.5376 2.23 30381 15354 2 1060.540241 531.2761 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3203.6 - 5.92E+06 - - - 2.5355 - 2.129 0.457 - 386.3 1 2 0 0.0027 9 0 0 0 2.45E+08 1.10E+08 - - - 4.6017 0.9877 230117_WJC_METTL3_WT_vs_EV_F04.15355.15355.2 0.445 14-Aug K.NVPYVFVR[166.11].S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 1002.5526 1.52 30382 15355 2 1002.553047 502.2836 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3203.6 - 3.09E+06 - - - 0.4249 - 1.328 0.076 - 224 1 2 0 0.0004 8 0 0 0 2.79E+08 1.84E+08 - - - 0.4578 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.15363.15363.2 0.00293 16-Nov K.LGEWVGLC[160.03]K[136.11].L sp|P25398|RS12_HUMAN 1 1068.5518 2.23 30388 15363 2 1068.553294 535.2832 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3204.5 - 2.82E+06 - - - 1.4431 - 2.093 0.461 - 385.2 1 2 0 0.0015 9 0 0 0 2.44E+08 1.10E+08 - - - 4.5823 0.9403 230117_WJC_METTL3_WT_vs_EV_F04.15365.15365.2 0.00772 16-Jul R.AVFPSIVGR[166.11].P "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 31 954.5526 1.26 30389 15365 2 954.554196 478.2836 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 9.79 3204.7 - 856562 - - - 1.65 - 1.61 0.303 - 167.1 1 1 0 0.0016 9 0 0 0 1.04E+09 8.26E+08 - - - 2.6562 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.15370.15370.2 0.00371 18-Aug K.SYLYPSTLVR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1207.6476 0.37 30392 15370 2 1207.650305 604.8311 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 3205.4 - 1.85E+06 - - - 2.2035 - 1.611 0.405 - 247.1 1 2 0 0.0027 10 0 0 0 3.89E+08 1.06E+09 - - - 3.3625 0.997 230117_WJC_METTL3_WT_vs_EV_F04.15371.15371.2 0.392 16-May R.LLDEYNLVR.S "sp|P46531|NOTC1_HUMAN,tr|A0A7P0T8U6|A0A7P0T8U6_HUMAN,tr|A0A7P0TA56|A0A7P0TA56_HUMAN,tr|A0A7P0TB20|A0A7P0TB20_HUMAN,tr|A0A7P0T8W1|A0A7P0T8W1_HUMAN" 5 1133.6081 4.96 30393 15371 2 1133.60841 567.8113 Neurogenic locus notch homolog protein 1 OS=Homo sapiens OX=9606 GN=NOTCH1 PE=1 SV=4 4.37 3205.5 - 153772 - - - 0.2964 - 1.222 0.265 - 57.9 1 2 0 0.0003 9 0 0 0 5.05E+06 1.02E+06 - - - 1.5782 0.999 230117_WJC_METTL3_WT_vs_EV_F04.15372.15372.2 0.0256 18-Sep K.SYLYPSTLVR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1197.6394 0.37 30394 15372 2 1197.638981 599.827 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 3205.6 - 540407 - - - -0.3281 - 1.804 0.316 - 319.2 1 2 0 -0.0004 10 0 0 0 3.89E+08 1.06E+09 - - - 3.0217 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.15373.15373.2 0.0436 18-Jun K.VLFTGVVDAR[166.11].G sp|Q14676|MDC1_HUMAN 1 1085.6109 2.58 30395 15373 2 1085.611652 543.8127 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 5.81 3205.7 - 400329 - - - 0.7249 - 1.429 0.291 - 106.2 1 2 0 0.0008 10 0 0 0 3.26E+07 1.27E+07 - - - 2.1865 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.15374.15374.2 0.000212 20-Sep R.LVEMASSLAIR.E "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1188.6536 3.5 30396 15374 2 1188.656692 595.3341 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3205.9 - 192107 - - - 2.5642 - 1.96 0.451 - 214.1 1 2 0 0.003 11 0 0 0 6.03E+06 1.73E+06 - - - 4.1916 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.15380.15380.2 0.00167 14-Aug R.GFTLVGMK[136.11].M "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 859.4717 0.96 30400 15380 2 859.473788 430.7431 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.75 3206.5 - 3.61E+06 - - - 2.4178 - 1.67 0.419 - 270.9 1 2 0 0.0021 8 0 0 0 8.08E+08 8.45E+08 - - - 3.6817 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.15387.15387.2 0.153 12-Jul K.TSILVFK[136.11].D sp|Q9BRS2|RIOK1_HUMAN 1 814.5044 0.63 30405 15387 2 814.506466 408.2595 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 8.41 3207.4 - 1.19E+06 - - - 2.5476 - 1.828 0.337 - 228.5 1 2 0 0.0021 7 0 0 0 3.44E+07 5.48E+07 - - - 3.4408 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.15389.15389.2 0.00241 14-Aug K.NVPYVFVR.S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 992.5444 0.88 30407 15389 2 992.545134 497.2795 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3207.6 - 1.77E+06 - - - 0.7889 - 1.332 0.419 - 257.4 1 2 0 0.0008 8 0 0 0 1.35E+08 1.54E+08 - - - 3.0001 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.15400.15400.2 0.0198 18-Jul K.VLFTGVVDAR.G sp|Q14676|MDC1_HUMAN 1 1075.6026 2.74 30415 15400 2 1075.602481 538.8086 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 5.81 3208.9 - 903254 - - - -0.106 - 1.768 0.335 - 174.4 1 2 0 -0.0001 10 0 0 0 3.75E+07 1.37E+07 - - - 3.1059 0.969 230117_WJC_METTL3_WT_vs_EV_F04.15404.15404.4 0.0486 Dec-96 T.LLLIILTDVFIISTVLR.L sp|Q8NGY0|O10X1_HUMAN 1 1941.2278 176.27 30418 15404 4 1941.236122 486.3142 Olfactory receptor 10X1 OS=Homo sapiens OX=9606 GN=OR10X1 PE=3 SV=2 5.84 3209.4 - 786557 - - - 4.2756 - 1.786 0.366 - 74.2 1 1 0 0.0083 17 0 0 0 9.20E+07 5.22E+05 - - - 2.6107 0.9925 230117_WJC_METTL3_WT_vs_EV_F04.15412.15412.2 0.228 14-Jun R.LQTFPLVR.H "sp|O96015|DNAL4_HUMAN,tr|B0QXZ5|B0QXZ5_HUMAN" 2 972.5757 10.85 30422 15412 2 972.577425 487.2951 Dynein axonemal light chain 4 OS=Homo sapiens OX=9606 GN=DNAL4 PE=1 SV=1 9.75 3210.6 - 355813 - - - 1.823 - 1.331 0.11 - 47.9 1 2 0 0.0018 8 0 0 0 5.91E+07 5.45E+06 - - - 0.7153 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.15416.15416.2 0.0131 22-Nov K.AVASAAAALVLK.A sp|Q9Y490|TLN1_HUMAN 1 1083.6652 1.2 30424 15416 2 1083.666148 542.8399 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.8 3211 - 187149 - - - 0.8794 - 2.015 0.377 - 297.6 1 2 0 0.001 12 0 0 0 2.77E+07 2.31E+07 - - - 3.6687 0.9899 230117_WJC_METTL3_WT_vs_EV_F04.15421.15421.2 0.0247 12-Jun K.LC[160.03]TFILK.N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 893.5045 1.25 30427 15421 2 893.506151 447.7595 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3211.6 - 873184 - - - 1.8914 - 1.285 0.092 - 70.9 1 2 0 0.0017 7 0 0 0 3.40E+07 2.72E+07 - - - 0.5145 0.9967 230117_WJC_METTL3_WT_vs_EV_F04.15423.15423.2 0.0294 12-Jul K.LC[160.03]TFILK[136.11].N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 901.5187 1.22 30429 15423 2 901.519218 451.7666 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3211.8 - 610974 - - - 0.6178 - 1.389 0.178 - 110.9 1 2 0 0.0006 7 0 0 0 3.24E+07 2.66E+07 - - - 1.3967 0.9826 230117_WJC_METTL3_WT_vs_EV_F04.15427.15427.2 14.7 14-Aug K.AGLSVLLK.A "sp|Q969N2|PIGT_HUMAN,tr|A0A1W2PRZ8|A0A1W2PRZ8_HUMAN,tr|H7C2Y2|H7C2Y2_HUMAN,tr|A0A1W2PPR6|A0A1W2PPR6_HUMAN,tr|A0A1W2PPS0|A0A1W2PPS0_HUMAN,tr|A0A1W2PR92|A0A1W2PR92_HUMAN,tr|A0A1W2PPI8|A0A1W2PPI8_HUMAN,tr|A0A1W2PRG1|A0A1W2PRG1_HUMAN,tr|A0A1W2PRV7|A0A1W2PRV7_HUMAN,tr|A0A1W2PQ52|A0A1W2PQ52_HUMAN,tr|A0A1W2PRH2|A0A1W2PRH2_HUMAN,tr|A0A1W2PNP0|A0A1W2PNP0_HUMAN,tr|A0A1W2PNW9|A0A1W2PNW9_HUMAN,tr|A0A1W2PP57|A0A1W2PP57_HUMAN,tr|A0A1W2PPQ7|A0A1W2PPQ7_HUMAN,tr|A0A1W2PQ29|A0A1W2PQ29_HUMAN,tr|A0A1W2PQN1|A0A1W2PQN1_HUMAN,tr|A0A1W2PPC3|A0A1W2PPC3_HUMAN" 18 799.5167 1.19 30431 15427 2 799.518207 400.7656 GPI transamidase component PIG-T OS=Homo sapiens OX=9606 GN=PIGT PE=1 SV=1 8.8 3212.3 - 321354 - - - 1.8349 - 1.201 0.073 - 112.3 1 2 0 0.0015 8 0 0 0 2.47E+07 2.07E+07 - - - 0.1321 0.9942 230117_WJC_METTL3_WT_vs_EV_F04.15435.15435.2 0.516 12-Jul R.ALTALFK.E "sp|Q9UBB4|ATX10_HUMAN,tr|A0A1W2PQD2|A0A1W2PQD2_HUMAN" 2 762.464 1.7 30434 15435 2 762.464384 382.2393 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 8.8 3213.4 - 794366 - - - 0.5351 - 1.29 0.153 - 161.5 1 2 0 0.0004 7 0 0 0 5.03E+07 2.96E+07 - - - 0.9778 0.9938 230117_WJC_METTL3_WT_vs_EV_F04.15445.15445.2 0.15 20-Jul R.SFMALSQDIQK.T "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1266.6278 0.58 30440 15445 2 1266.630655 634.3212 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 5.55 3214.6 - 41805.4 - - - 2.2359 - 1.381 0.142 - 118.1 1 2 0 0.0028 11 0 0 0 1.04E+06 1.81E+06 - - - 0.9622 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.15453.15453.2 0.355 14-Aug R.IGQFVFAR.D sp|Q9NRN7|ADPPT_HUMAN 1 936.5181 8.66 30445 15453 2 936.518617 469.2663 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2 9.75 3215.5 - 4.15E+06 - - - 0.5125 - 1.786 0.291 - 195.4 1 2 0 0.0005 8 0 0 0 1.27E+08 1.47E+07 - - - 2.9394 0.9928 230117_WJC_METTL3_WT_vs_EV_F04.15455.15455.2 0.412 12-Jul R.FLVTVIK.D "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 818.5266 1.63 30446 15455 2 818.529275 410.2706 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3215.7 - 532337 - - - 3.2974 - 1.344 0.18 - 170.2 1 2 0 0.0027 7 0 0 0 1.14E+08 6.98E+07 - - - 1.3064 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.15456.15456.2 0.00672 22-Nov R.EHALLAYTLGVK.Q "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 11 1313.7343 4.6 30447 15456 2 1313.739383 657.8744 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.85 3215.9 - 132059 - - - 3.841 - 1.789 0.296 - 177.1 1 2 0 0.005 12 0 0 0 5.56E+06 1.21E+06 - - - 2.7561 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.15462.15462.2 0.195 12-Jun R.ALTALFK[136.11].E "sp|Q9UBB4|ATX10_HUMAN,tr|A0A1W2PQD2|A0A1W2PQD2_HUMAN" 2 770.4782 1.71 30451 15462 2 770.479516 386.2464 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 8.8 3216.6 - 904224 - - - 1.7392 - 1.316 0.188 - 132 1 2 0 0.0013 7 0 0 0 5.05E+07 2.96E+07 - - - 1.2992 0.9815 230117_WJC_METTL3_WT_vs_EV_F04.15464.15464.2 10.6 12-Jul R.LILEALK[136.11].Q "sp|Q8IX18|DHX40_HUMAN,sp|Q6TDP4|KLH17_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|D6RJB0|D6RJB0_HUMAN,tr|H0Y9K3|H0Y9K3_HUMAN,tr|A0A3B3ISF8|A0A3B3ISF8_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN,tr|Q0VGE6|Q0VGE6_HUMAN,tr|J3QLT4|J3QLT4_HUMAN,tr|A0A3B3IT29|A0A3B3IT29_HUMAN,tr|D6R9W6|D6R9W6_HUMAN,tr|G3V0E9|G3V0E9_HUMAN" 12 806.5357 1.24 30453 15464 2 806.535484 404.2751 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 6 3216.8 - 787162 - - - -0.2567 - 1.226 0.098 - 126 1 2 0 -0.0002 7 0 0 0 3.47E+07 2.80E+07 - - - 0.4104 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.15472.15472.2 0.0134 14-Aug R.LLEC[160.03]YFTR[166.11].S "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1110.5407 2.12 30457 15472 2 1110.541681 556.2776 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.99 3217.8 - 235711 - - - 0.8509 - 1.528 0.334 - 174.3 1 2 0 0.0009 8 0 0 0 2.59E+07 1.22E+07 - - - 2.7863 0.9458 230117_WJC_METTL3_WT_vs_EV_F04.15483.15483.2 0.00126 14-Sep R.LYNYFYDR.R "sp|Q96GD4|AURKB_HUMAN,tr|J3QR41|J3QR41_HUMAN,tr|J3QLN8|J3QLN8_HUMAN,tr|J3KTD6|J3KTD6_HUMAN,tr|J3KT86|J3KT86_HUMAN" 5 1152.524 1.63 30465 15483 2 1153.529674 577.2693 Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3 5.83 3219.1 - 136870 - - - 872.5753 - 1.518 0.415 - 300.2 1 2 0 1.0057 8 0 0 0 7.43E+06 4.57E+06 - - - 3.0493 0.9931 230117_WJC_METTL3_WT_vs_EV_F04.15490.15490.2 0.251 12-Jul R.C[160.03]ILPFDK[136.11].E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 899.4666 1.29 30469 15490 2 899.466972 450.7406 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.83 3219.8 - 1.07E+06 - - - 0.3858 - 1.263 0.15 - 216.5 1 2 0 0.0003 7 0 0 0 1.51E+08 1.17E+08 - - - 0.8886 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.15493.15493.2 0.0189 12-Aug K.YIQELWR.K "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1006.5236 0.77 30470 15493 2 1006.523653 504.2691 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 6 3220.2 - 1.79E+06 - - - 0.0368 - 1.538 0.359 - 259 1 2 0 0 7 0 0 0 1.32E+08 1.70E+08 - - - 3.0566 0.9947 230117_WJC_METTL3_WT_vs_EV_F04.15495.15495.2 0.0194 12-Jul K.YIQELWR[166.11].K "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1016.5319 0.77 30471 15495 2 1016.529323 509.2732 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 6 3220.4 - 5.83E+06 - - - -2.5213 - 1.481 0.328 - 164.1 1 2 0 -0.0026 7 0 0 0 1.31E+08 1.70E+08 - - - 2.7072 0.9903 230117_WJC_METTL3_WT_vs_EV_F04.15497.15497.2 4.02 12-Jul R.LWISVAR[166.11].Y sp|Q15029|U5S1_HUMAN 1 853.5049 1.55 30473 15497 2 853.505018 427.7597 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 9.75 3220.6 - 5.15E+06 - - - 0.0879 - 1.325 0.109 - 226.9 1 2 0 0.0001 7 0 0 0 1.86E+08 1.19E+08 - - - 0.7377 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.15502.15502.2 0.928 14-Aug R.GLVVPVIR[166.11].N sp|P36957|ODO2_HUMAN 1 861.5675 0.9 30476 15502 2 861.56761 431.791 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3221.2 - 2.13E+06 - - - 0.0778 - 1.585 0.245 - 344.7 1 2 0 0.0001 8 0 0 0 8.34E+07 9.28E+07 - - - 2.2397 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.15505.15505.2 0.000184 22-Oct K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.14 30478 15505 2 1277.750585 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3221.5 - 664620 - - - 0.7764 - 1.868 0.384 - 198.2 1 2 0 0.001 12 0 0 0 2.71E+07 2.38E+07 - - - 3.521 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.15508.15508.2 3.16E-05 20-Oct K.WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1223.643 0.9 30480 15508 2 1223.641472 612.8288 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3221.9 - 326700 - - - -1.2561 - 1.86 0.519 - 182.5 1 2 0 -0.0015 11 0 0 0 4.77E+07 5.27E+07 - - - 4.5527 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.15518.15518.2 0.0882 22-Aug K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.15 30484 15518 2 1287.759852 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3223.2 - 654472 - - - 1.5445 - 1.637 0.263 - 118.7 1 2 0 0.002 12 0 0 0 2.80E+07 2.43E+07 - - - 2.2797 0.9571 230117_WJC_METTL3_WT_vs_EV_F04.15520.15520.2 0.145 14-Jun K.VFPLAEYR.T sp|Q86T24|KAISO_HUMAN 1 993.5284 6.48 30486 15520 2 993.525256 497.7715 Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2 5.97 3223.3 - 378179 - - - -3.1313 - 1.27 0.181 - 130.1 1 2 0 -0.0031 8 0 0 0 2.26E+07 3.49E+06 - - - 1.0978 0.9882 230117_WJC_METTL3_WT_vs_EV_F04.15526.15526.2 0.0941 12-Jul R.IGVITNR[166.11].E sp|P62701|RS4X_HUMAN 1 781.4686 3.07 30488 15526 2 781.469749 391.7416 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 3224.1 - 1.19E+06 - - - 1.5253 - 1.492 0.007 - 143.8 1 2 0 0.0012 7 0 0 0 6.96E+07 2.27E+07 - - - 0.3601 0.997 230117_WJC_METTL3_WT_vs_EV_F04.15528.15528.2 0.0183 14-Jul K.FLILNPSK.R "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 930.5539 0.37 30490 15528 2 930.554229 466.2842 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 8.75 3224.4 - 854314 - - - 0.403 - 1.232 0.251 - 118.3 1 2 0 0.0004 8 0 0 0 1.70E+07 4.64E+07 - - - 1.524 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.15535.15535.2 1.17 14-Aug R.GLVVPVIR.N sp|P36957|ODO2_HUMAN 1 851.5593 0.9 30495 15535 2 851.55891 426.7869 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3225.3 - 5.02E+06 - - - -0.4263 - 1.61 0.212 - 341.8 1 2 0 -0.0004 8 0 0 0 8.34E+07 9.28E+07 - - - 2.043 0.9943 230117_WJC_METTL3_WT_vs_EV_F04.15536.15536.2 0.119 14-Aug R.LLFGPTVR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 911.5468 0.88 30496 15536 2 911.54656 456.7807 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3225.4 - 2.97E+06 - - - -0.2721 - 1.349 0.182 - 197.3 1 2 0 -0.0002 8 0 0 0 6.58E+07 7.44E+07 - - - 1.288 1 230117_WJC_METTL3_WT_vs_EV_F04.15538.15538.2 1.69E-05 20-Dec K.WEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1215.6288 0.88 30498 15538 2 1215.629042 608.8217 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3225.6 - 913994 - - - 0.1917 - 2.115 0.535 - 276.1 1 2 0 0.0002 11 0 0 0 4.77E+07 5.41E+07 - - - 5.0188 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.15539.15539.2 0.0272 18-Nov K.ALVLTEIGPK.R sp|O14732|IMPA2_HUMAN 1 1039.6277 126.93 30499 15539 2 1039.628909 520.8211 Inositol monophosphatase 2 OS=Homo sapiens OX=9606 GN=IMPA2 PE=1 SV=1 6.05 3225.8 - 505853 - - - 1.1177 - 1.921 0.344 - 350.2 1 2 0 0.0012 10 0 0 0 9.29E+06 7.32E+04 - - - 3.4037 0.9788 230117_WJC_METTL3_WT_vs_EV_F04.15544.15544.2 1.8 16-Jun K.FVPLLPGNR.S sp|P78527|PRKDC_HUMAN 1 1011.5866 1.02 30502 15544 2 1011.588529 506.8006 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3226.3 - 1.01E+06 - - - 1.9553 - 1.153 0.077 - 129.6 1 2 0 0.002 9 0 0 0 5.10E+07 4.99E+07 - - - 0.021 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.15546.15546.2 0.0619 16-Aug R.LIVNVNDLR[166.11].R sp|P25205|MCM3_HUMAN 1 1064.6218 4.24 30504 15546 2 1064.622421 533.3182 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.84 3226.4 - 1.51E+06 - - - 0.6171 - 1.437 0.263 - 186.8 1 2 0 0.0007 9 0 0 0 1.09E+08 2.58E+07 - - - 2.0322 0.9676 230117_WJC_METTL3_WT_vs_EV_F04.15547.15547.2 0.826 16-Jun K.FVPLLPGNR[166.11].S sp|P78527|PRKDC_HUMAN 1 1021.5948 1.02 30505 15547 2 1021.594913 511.8047 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3226.5 - 1.12E+06 - - - 0.0901 - 1.135 0.067 - 131.4 1 2 0 0.0001 9 0 0 0 5.10E+07 4.99E+07 - - - -0.0978 0.9848 230117_WJC_METTL3_WT_vs_EV_F04.15554.15554.2 1.54 14-Jul R.LLPEQLIK[136.11].E "sp|Q92621|NU205_HUMAN,sp|Q8TBZ9|TEX47_HUMAN" 2 960.6099 0.75 30509 15554 2 960.609618 481.3122 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 6 3227.4 - 540453 - - - -0.3123 - 1.004 0.206 - 91.2 1 2 0 -0.0003 8 0 0 0 1.82E+07 2.42E+07 - - - 0.5745 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.15557.15557.2 0.0027 16-Jul K.LITWSPVC[160.03]R.N "sp|P07203|GPX1_HUMAN,tr|A0A2R8Y6B6|A0A2R8Y6B6_HUMAN" 2 1130.5907 3.03 30512 15557 2 1130.590352 566.3026 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 8.25 3227.8 - 296102 - - - -0.2636 - 1.52 0.323 - 161 1 2 0 -0.0003 9 0 0 0 1.23E+07 4.08E+06 - - - 2.6379 0.9946 230117_WJC_METTL3_WT_vs_EV_F04.15560.15560.2 0.0776 12-Jun M.GVPAFFR.W sp|Q9H0D6|XRN2_HUMAN 1 792.4283 0.82 30514 15560 2 792.429996 397.2214 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 3228.1 - 788597 - - - 2.192 - 1.08 0.239 - 171.1 1 2 0 0.0017 7 0 0 0 1.90E+08 2.31E+08 - - - 1.0496 0.9954 230117_WJC_METTL3_WT_vs_EV_F04.15562.15562.2 0.273 16-Aug R.VVLGEFGVR[166.11].N "sp|O15160|RPAC1_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 6 984.5632 8.85 30515 15562 2 984.564163 493.2889 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 5.97 3228.3 - 2.25E+06 - - - 0.9923 - 1.531 0.134 - 187.6 3 2 0 0.001 9 0 0 0 6.80E+08 7.68E+07 - - - 1.0495 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.15565.15565.2 0.00112 16-Aug K.LLPDTILEK[136.11].L "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1048.626 0.8 30518 15565 2 1048.626654 525.3203 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 4.37 3228.7 - 827646 - - - 0.6599 - 1.6 0.434 - 161.5 1 2 0 0.0007 9 0 0 0 1.00E+08 1.26E+08 - - - 3.6061 0.9925 230117_WJC_METTL3_WT_vs_EV_F04.15569.15569.2 0.733 14-May R.LLFGPTVR.L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 901.5385 0.74 30520 15569 2 901.539682 451.7765 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3229.2 - 3.52E+06 - - - 1.2689 - 1.078 0.19 - 72.2 1 2 0 0.0011 8 0 0 0 6.60E+07 8.97E+07 - - - 0.6705 0.8948 230117_WJC_METTL3_WT_vs_EV_F04.15580.15580.2 4.55 14-Jun K.FLILNPSK[136.11].R "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 938.5681 0.36 30528 15580 2 938.570006 470.2913 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 8.75 3230.3 - 549731 - - - 2.0798 - 0.973 0.023 - 71.2 2 2 0 0.002 8 0 0 0 1.67E+07 4.64E+07 - - - -1.0068 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.15581.15581.2 0.0156 18-Jun K.EIVPVLVSTR.K sp|Q9BWD1|THIC_HUMAN 1 1111.6601 1.07 30529 15581 2 1111.66053 556.8373 "Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2" 6.1 3230.4 - 274991 - - - 0.3778 - 1.504 0.267 - 78.8 1 2 0 0.0004 10 0 0 0 2.21E+06 2.06E+06 - - - 2.1521 0.9783 230117_WJC_METTL3_WT_vs_EV_F04.15588.15588.2 3.03 14-May K.LAVSSLLR.V "sp|Q7Z3U7|MON2_HUMAN,tr|A0A286YFF8|A0A286YFF8_HUMAN" 2 857.5335 1.55 30534 15588 2 857.534584 429.774 Protein MON2 homolog OS=Homo sapiens OX=9606 GN=MON2 PE=1 SV=3 9.75 3231.3 - 752533 - - - 1.3201 - 1.197 0.107 - 51.2 9 2 0 0.0011 8 0 0 0 1.27E+07 8.18E+06 - - - -0.053 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.15590.15590.2 0.00045 16-Oct K.YMTDGMLLR[166.11].E "sp|Q14562|DHX8_HUMAN,sp|O60231|DHX16_HUMAN,sp|O43143|DHX15_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|F5H658|F5H658_HUMAN" 5 1108.5285 1.17 30536 15590 2 1108.531727 555.2715 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 5.84 3231.5 - 314584 - - - 2.9499 - 1.625 0.538 - 369.2 1 2 0 0.0033 9 0 0 0 2.39E+07 2.04E+07 - - - 4.4182 0.991 230117_WJC_METTL3_WT_vs_EV_F04.15594.15594.2 0.0573 14-Jul R.FAPPLVIK.E sp|P04181|OAT_HUMAN 1 883.5531 1.35 30538 15594 2 883.555962 442.7838 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 8.75 3232 - 957935 - - - 3.2109 - 1.114 0.233 - 148.2 1 2 0 0.0028 8 0 0 0 3.20E+07 2.37E+07 - - - 1.0866 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.15603.15603.2 0.0865 18-Aug K.LIESAEELIR[166.11].D "sp|Q13217|DNJC3_HUMAN,tr|X6R9L0|X6R9L0_HUMAN" 2 1181.6531 1.53 30544 15603 2 1181.655267 591.8338 DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1 4.25 3233.2 - 355098 - - - 1.8144 - 1.783 0.271 - 153 1 2 0 0.0021 10 0 0 0 8.10E+06 5.27E+06 - - - 2.6561 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.15604.15604.2 0.0454 16-Aug K.LISEEDLLR.K "sp|P01106|MYC_HUMAN,tr|A0A087WUS5|A0A087WUS5_HUMAN,tr|A0A494C1T8|A0A494C1T8_HUMAN,tr|H0YBT0|H0YBT0_HUMAN" 4 1086.5921 0.13 30545 15604 2 1086.595444 544.3033 Myc proto-oncogene protein OS=Homo sapiens OX=9606 GN=MYC PE=1 SV=1 4.14 3233.3 - 311580 - - - 3.0867 - 1.548 0.339 - 147.4 1 2 0 0.0034 9 0 0 0 8.04E+06 6.22E+07 - - - 2.808 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.15612.15612.2 0.00767 18-Dec K.LIESAEELIR.D "sp|Q13217|DNJC3_HUMAN,tr|X6R9L0|X6R9L0_HUMAN" 2 1171.6449 1.53 30551 15612 2 1171.644343 586.8297 DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1 4.25 3234.3 - 853558 - - - -0.4353 - 2.347 0.245 - 421.7 1 2 0 -0.0005 10 0 0 0 8.10E+06 5.27E+06 - - - 3.2318 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.15614.15614.2 1.62E-05 18-Oct K.LLANMVYQYK[136.11].G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1249.662 1.7 30553 15614 2 1249.662308 625.8383 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3234.5 - 275516 - - - 0.2225 - 1.776 0.515 - 361.6 1 2 0 0.0003 10 0 0 0 1.80E+07 1.06E+07 - - - 4.4479 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.15620.15620.2 0.00494 16-Aug R.LFEGNALLR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1031.5764 0.88 30557 15620 2 1031.579327 516.7955 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3235.2 - 6.81E+06 - - - 2.8568 - 1.785 0.412 - 231.1 1 2 0 0.0029 9 0 0 0 9.65E+08 1.10E+09 - - - 3.7594 0.996 230117_WJC_METTL3_WT_vs_EV_F04.15622.15622.2 0.049 16-Jul R.LFEGNALLR[166.11].R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1041.5847 0.88 30559 15622 2 1041.582522 521.7996 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3235.4 - 8.81E+06 - - - -2.043 - 1.452 0.35 - 111.2 1 2 0 -0.0021 9 0 0 0 9.62E+08 1.09E+09 - - - 2.7044 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.15624.15624.2 0.0136 16-Sep R.VLGMTLIQK[136.11].C sp|Q04760|LGUL_HUMAN 1 1009.6085 1.31 30561 15624 2 1009.611144 505.8115 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3235.5 - 1.80E+06 - - - 2.5812 - 1.68 0.27 - 201.7 1 2 0 0.0026 9 0 0 0 2.82E+07 2.15E+07 - - - 2.5353 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.15627.15627.2 0.213 14-Aug K.MLLSLPEK.V "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 929.5256 1.06 30564 15627 2 929.526538 465.7701 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 5.75 3235.9 - 633410 - - - 1.0199 - 1.665 0.142 - 213.5 1 2 0 0.0009 8 0 0 0 1.26E+07 1.19E+07 - - - 1.6271 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.15628.15628.2 0.00671 18-Aug R.LVPC[160.03]ILEAAK.Q "sp|Q96ER3|SAAL1_HUMAN,tr|H0YCN7|H0YCN7_HUMAN,tr|H0YEK5|H0YEK5_HUMAN,tr|J3KND1|J3KND1_HUMAN,tr|E9PMD2|E9PMD2_HUMAN,tr|E9PRZ1|E9PRZ1_HUMAN" 6 1112.6264 1.64 30565 15628 2 1112.630315 557.3205 Protein SAAL1 OS=Homo sapiens OX=9606 GN=SAAL1 PE=1 SV=2 5.99 3236 - 573189 - - - 3.5484 - 1.41 0.353 - 164.3 1 2 0 0.0039 10 0 0 0 6.45E+06 3.94E+06 - - - 2.6061 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.15633.15633.2 0.000179 14-Sep K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 1.77 30568 15633 2 895.482049 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3236.6 - 3.13E+06 - - - 1.8928 - 1.892 0.45 - 204.7 1 2 0 0.0017 8 0 0 0 2.49E+09 1.40E+09 - - - 4.2872 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.15634.15634.2 0.0882 16-Sep R.VLGMTLIQK.C sp|Q04760|LGUL_HUMAN 1 1001.5943 1.31 30569 15634 2 1001.596183 501.8044 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3236.7 - 1.30E+06 - - - 1.8421 - 1.883 0.235 - 198.4 1 2 0 0.0018 9 0 0 0 2.82E+07 2.15E+07 - - - 2.607 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.15644.15644.2 0.0841 14-Jul K.MLLSLPEK[136.11].V "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 937.5398 1.05 30577 15644 2 937.541816 469.7772 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 5.75 3237.8 - 970125 - - - 2.161 - 1.552 0.274 - 171 1 2 0 0.002 8 0 0 0 1.24E+07 1.19E+07 - - - 2.3898 0.8909 230117_WJC_METTL3_WT_vs_EV_F04.15646.15646.2 0.154 12-Sep L.FGDLLLK[136.11].Q "sp|Q15147|PLCB4_HUMAN,sp|Q6P2Q9|PRP8_HUMAN,tr|A0A7P0MRI8|A0A7P0MRI8_HUMAN" 3 812.4887 1.24 30579 15646 2 812.488721 407.2516 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4 PE=1 SV=3" 5.84 3238.1 - 796698 - - - -0.0246 - 1.848 0.185 - 202.3 1 1 0 0 7 0 0 0 1.43E+08 1.15E+08 - - - 2.3532 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.15647.15647.2 2.83E-05 20-Nov R.VIGTLLGTVDK[136.11].H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1122.674 1.11 30580 15647 2 1122.67667 562.3443 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3238.2 - 650430 - - - 2.4005 - 2.122 0.395 - 239.8 1 2 0 0.0027 11 0 0 0 9.33E+07 8.40E+07 - - - 3.9929 0.992 230117_WJC_METTL3_WT_vs_EV_F04.15649.15649.2 1.59 14-Nov R.IAVPVLVR[166.11].D sp|P52952|NKX25_HUMAN 1 875.5832 2.04 30582 15649 2 875.58541 438.7989 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 9.75 3238.5 - 333912 - - - 2.532 - 1.519 0.077 - 513.2 1 2 0 0.0022 8 0 0 0 2.17E+07 1.07E+07 - - - 0.8699 0.9942 230117_WJC_METTL3_WT_vs_EV_F04.15650.15650.2 0.0242 14-Jul K.VFNLGVYR.R "sp|O60825|F262_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN" 2 966.5287 0.54 30583 15650 2 966.531999 484.2716 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 8.72 3238.6 - 207294 - - - 3.4122 - 1.497 0.175 - 112.7 1 2 0 0.0033 8 0 0 0 2.46E+07 4.55E+07 - - - 1.5493 0.9891 230117_WJC_METTL3_WT_vs_EV_F04.15656.15656.2 0.0832 16-May R.FLPSPVVIK[136.11].K "sp|Q13618|CUL3_HUMAN,tr|H7C399|H7C399_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 3 1006.6307 0.63 30587 15656 2 1006.632188 504.3226 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 8.75 3239.2 - 1.77E+06 - - - 1.5239 - 1.056 0.207 - 75.1 5 2 0 0.0015 9 0 0 0 4.25E+07 6.78E+07 - - - 0.4148 1 230117_WJC_METTL3_WT_vs_EV_F04.15657.15657.2 0.000352 20-Oct R.VIGTLLGTVDK.H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1114.6598 1.11 30588 15657 2 1114.662088 558.3372 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3239.3 - 1.07E+06 - - - 2.0751 - 2.239 0.529 - 213.9 1 2 0 0.0023 11 0 0 0 9.33E+07 8.40E+07 - - - 5.128 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.15659.15659.2 0.221 14-Sep R.IAVPVLVR.D sp|P52952|NKX25_HUMAN 1 865.5749 1.97 30590 15659 2 865.576172 433.7947 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 9.75 3239.5 - 704599 - - - 1.443 - 1.734 0.317 - 335.9 1 2 0 0.0012 8 0 0 0 2.11E+07 1.07E+07 - - - 3.042 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.15663.15663.2 0.12 12-Jun R.GFFNGLR[166.11].T "sp|Q9Y394|DHRS7_HUMAN,tr|H0YJ66|H0YJ66_HUMAN,tr|H0YJE4|H0YJE4_HUMAN,tr|H0YJR8|H0YJR8_HUMAN" 4 819.4267 1.43 30594 15663 2 819.427273 410.7206 Dehydrogenase\reductase SDR family member 7 OS=Homo sapiens OX=9606 GN=DHRS7 PE=1 SV=1 9.75 3240.1 - 315859 - - - 0.7078 - 1.294 0.226 - 137 1 2 0 0.0006 7 0 0 0 6.73E+06 4.71E+06 - - - 1.5267 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.15665.15665.2 0.0522 12-Jun M.GVPAFFR[166.11].W sp|Q9H0D6|XRN2_HUMAN 1 802.4365 0.82 30595 15665 2 802.437488 402.2255 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 3240.3 - 3.16E+06 - - - 1.1951 - 1.322 0.293 - 145 1 2 0 0.001 7 0 0 0 1.90E+08 2.32E+08 - - - 2.0893 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.15667.15667.2 0.00216 14-Jul K.FVADGIFK[136.11].A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 903.4946 1.77 30596 15667 2 903.494527 452.7546 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3240.5 - 4.66E+07 - - - -0.0299 - 1.51 0.383 - 125.4 1 2 0 0 8 0 0 0 2.49E+09 1.40E+09 - - - 3.1127 0.9646 230117_WJC_METTL3_WT_vs_EV_F04.15668.15668.2 2.38 16-Jun R.FLPSPVVIK.K "sp|Q13618|CUL3_HUMAN,tr|H7C399|H7C399_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 3 998.6165 0.61 30597 15668 2 998.616645 500.3155 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 8.75 3240.6 - 2.04E+06 - - - 0.1913 - 1.182 0.057 - 97.9 2 2 0 0.0002 9 0 0 0 4.10E+07 6.70E+07 - - - -0.1888 1 230117_WJC_METTL3_WT_vs_EV_F04.15671.15671.2 5.61E-06 20-Dec R.LFSGDVVLTAR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1186.6585 0.98 30600 15671 2 1186.655865 594.3365 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3241 - 477028 - - - -2.2568 - 2.192 0.535 - 469.6 1 2 0 -0.0027 11 0 0 0 1.98E+08 2.01E+08 - - - 5.1148 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.15673.15673.2 0.0065 18-Oct R.IVLVDDSIVR[166.11].G sp|Q06203|PUR1_HUMAN 1 1137.6633 2.03 30602 15673 2 1137.662694 569.8389 Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1 4.21 3241.3 - 345595 - - - -0.5274 - 1.814 0.432 - 301.5 1 2 0 -0.0006 10 0 0 0 4.22E+07 2.07E+07 - - - 3.8939 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.15675.15675.2 0.00602 14-Sep K.VFNLGVYR[166.11].R "sp|O60825|F262_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN" 2 976.537 0.56 30603 15675 2 976.537415 489.2758 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 8.72 3241.5 - 1.83E+06 - - - 0.4547 - 1.771 0.206 - 330.2 1 2 0 0.0004 8 0 0 0 2.54E+07 4.55E+07 - - - 2.2861 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.15678.15678.2 1.43 14-Sep K.NLYIISVK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 956.5786 1.3 30605 15678 2 956.579405 479.2966 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3241.8 - 901494 - - - 0.8227 - 1.593 0.099 - 330.4 1 2 0 0.0008 8 0 0 0 2.94E+09 2.26E+09 - - - 1.1763 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.15680.15680.2 0.0328 14-Jul R.FVDGLTFK.V "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 925.4909 0.84 30607 15680 2 925.491974 463.7527 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.84 3241.9 - 526415 - - - 1.1399 - 1.258 0.337 - 126.1 1 2 0 0.0011 8 0 0 0 1.03E+07 1.22E+07 - - - 2.222 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.15682.15682.2 0.354 16-Aug R.LWGEPVNLR.E "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 1082.5873 1.43 30609 15682 2 1082.588518 542.3009 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 6 3242.1 - 343918 - - - 1.1445 - 1.616 0.12 - 216.5 1 2 0 0.0012 9 0 0 0 1.08E+07 7.54E+06 - - - 1.3155 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.15685.15685.2 0.222 14-Sep K.NLYIISVK.G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 948.5644 1.3 30610 15685 2 948.565407 475.2895 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3242.5 - 4.39E+06 - - - 1.0426 - 1.57 0.248 - 333.3 1 2 0 0.001 8 0 0 0 2.94E+09 2.26E+09 - - - 2.2328 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.15686.15686.2 0.751 18-Oct R.IVLVDDSIVR.G sp|Q06203|PUR1_HUMAN 1 1127.655 2.04 30611 15686 2 1127.656611 564.8348 Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1 4.21 3242.6 - 1.02E+06 - - - 1.4073 - 1.893 0.192 - 370.4 1 2 0 0.0016 10 0 0 0 4.24E+07 2.07E+07 - - - 2.2399 0.9728 230117_WJC_METTL3_WT_vs_EV_F04.15687.15687.2 2.13 14-May R.SLVSGLIR.L sp|Q92616|GCN1_HUMAN 1 843.5178 1.2 30612 15687 2 843.51816 422.7662 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.47 3242.6 - 2.21E+06 - - - 0.4244 - 1.082 0.087 - 105.4 1 2 0 0.0004 8 0 0 0 4.41E+07 3.69E+07 - - - -0.0788 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.15688.15688.2 0.065 14-Jul R.LLPSLIGR[166.11].H "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 4 877.5625 0.75 30613 15688 2 877.562891 439.7885 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 9.75 3242.7 - 1.03E+06 - - - 0.4934 - 1.378 0.294 - 197 1 2 0 0.0004 8 0 0 0 5.93E+07 7.90E+07 - - - 2.1794 0.9714 230117_WJC_METTL3_WT_vs_EV_F04.15690.15690.2 0.76 14-Jul R.LLPSLIGR.H "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 4 867.5542 0.75 30615 15690 2 867.552059 434.7844 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 9.75 3242.9 - 675409 - - - -2.454 - 1.093 0.242 - 164.9 1 2 0 -0.0021 8 0 0 0 5.93E+07 7.90E+07 - - - 1.0959 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.15691.15691.2 0.0788 18-Jul R.LIYTAGGYFR.Q sp|Q14145|KEAP1_HUMAN 1 1159.6026 2.16 30616 15691 2 1159.605114 580.8086 Kelch-like ECH-associated protein 1 OS=Homo sapiens OX=9606 GN=KEAP1 PE=1 SV=2 8.59 3243 - 381865 - - - 2.1723 - 1.309 0.34 - 135.3 1 2 0 0.0025 10 0 0 0 6.13E+06 2.84E+06 - - - 2.303 0.9899 230117_WJC_METTL3_WT_vs_EV_F04.15694.15694.2 2.09 12-Aug K.LLTSLLK.Q sp|O60763|USO1_HUMAN 1 786.5215 0.5 30617 15694 2 786.524156 394.268 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 8.75 3243.4 - 460517 - - - 3.3883 - 1.505 0.101 - 140 1 2 0 0.0027 7 0 0 0 1.19E+07 2.36E+07 - - - 1.0814 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.15695.15695.2 1.66E-05 26-Sep K.VLEQLTGQTPVFSK.A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1545.8403 1.34 30618 15695 2 1545.845278 773.9274 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3243.5 - 157302 - - - 3.2468 - 2.196 0.446 - 127.1 1 2 0 0.005 14 0 0 0 5.32E+06 3.98E+06 - - - 4.3076 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.15697.15697.2 0.00624 14-Sep R.LFC[160.03]VGFTK[136.11].K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 978.5088 0.83 30620 15697 2 978.50928 490.2617 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.22 3243.6 - 1.93E+06 - - - 0.466 - 1.464 0.345 - 231 1 2 0 0.0005 8 0 0 0 2.72E+08 3.26E+08 - - - 2.7386 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.15698.15698.2 0.0138 14-Aug R.LFC[160.03]VGFTK.K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 970.4946 0.83 30621 15698 2 970.495538 486.2546 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.22 3243.7 - 1.18E+06 - - - 0.9418 - 1.642 0.376 - 179.4 1 2 0 0.0009 8 0 0 0 2.72E+08 3.26E+08 - - - 3.3135 1 230117_WJC_METTL3_WT_vs_EV_F04.15702.15702.2 2.43E-06 13/26 K.VLEQLTGQTPVFSK[136.11].A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1553.8545 1.34 30625 15702 2 1553.852603 777.9345 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3244.2 - 73713 - - - -1.1944 - 2.605 0.546 - 667.5 1 2 0 -0.0019 14 0 0 0 5.32E+06 3.98E+06 - - - 5.4758 0.9962 230117_WJC_METTL3_WT_vs_EV_F04.15705.15705.2 0.0229 12-Jul K.FVSELWK[136.11].D sp|P35579|MYH9_HUMAN 1 915.4946 0.64 30626 15705 2 915.492694 458.7546 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6 3244.6 - 6.12E+06 - - - -2.0317 - 1.471 0.335 - 117.2 1 2 0 -0.0019 7 0 0 0 8.19E+07 1.27E+08 - - - 2.7376 0.9776 230117_WJC_METTL3_WT_vs_EV_F04.15707.15707.2 0.377 14-Jun K.AVIELLEK[136.11].S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|H0Y327|H0Y327_HUMAN,tr|Q5JYA8|Q5JYA8_HUMAN,tr|Q5JYA3|Q5JYA3_HUMAN" 6 921.5626 2.54 30628 15707 2 921.56253 461.7886 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.53 3244.7 - 1.02E+06 - - - -0.1129 - 1.375 0.059 - 76.5 3 2 0 -0.0001 8 0 0 0 5.29E+07 2.08E+07 - - - 0.2241 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.15708.15708.2 0.00464 22-Sep R.VLVTGATGLLGR.A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1155.6976 1.6 30629 15708 2 1155.699514 578.8561 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3244.9 - 979177 - - - 1.6925 - 1.742 0.46 - 187.3 1 2 0 0.002 12 0 0 0 2.46E+07 1.54E+07 - - - 3.8983 1 230117_WJC_METTL3_WT_vs_EV_F04.15709.15709.2 0.000681 14/22 R.VLVTGATGLLGR[166.11].A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1165.7058 1.6 30630 15709 2 1165.705433 583.8602 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3245 - 778551 - - - -0.3389 - 2.401 0.492 - 707.8 1 2 0 -0.0004 12 0 0 0 2.46E+07 1.54E+07 - - - 4.9794 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.15710.15710.2 0.00381 16-Aug K.LIPPQDILR[166.11].D sp|Q96A65|EXOC4_HUMAN 1 1073.6472 1.58 30631 15710 2 1073.649045 537.8309 Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1 5.84 3245.1 - 419944 - - - 1.6719 - 1.432 0.342 - 153.1 1 2 0 0.0018 9 0 0 0 1.72E+07 1.09E+07 - - - 2.6053 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.15715.15715.2 0.011 14-Oct R.TVETLLLR.F "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 6 943.5702 0.53 30634 15715 2 943.571344 472.7924 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 5.66 3245.8 - 1.32E+06 - - - 1.1785 - 1.759 0.304 - 310.8 1 2 0 0.0011 8 0 0 0 7.75E+07 1.47E+08 - - - 2.9892 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.15719.15719.2 0.0368 18-Jun R.LVPLQEEIYR.K "sp|Q2NKX8|ERC6L_HUMAN,tr|B5MDQ0|B5MDQ0_HUMAN" 2 1258.6921 5.23 30638 15719 2 1258.695072 630.3533 DNA excision repair protein ERCC-6-like OS=Homo sapiens OX=9606 GN=ERCC6L PE=1 SV=1 4.53 3246.3 - 176549 - - - 2.331 - 1.324 0.26 - 167 1 2 0 0.0029 10 0 0 0 7.55E+06 1.44E+06 - - - 1.7438 0.9969 230117_WJC_METTL3_WT_vs_EV_F04.15723.15723.2 0.0332 16-Jun R.FFMGNQVLK[136.11].V sp|P13010|XRCC5_HUMAN 1 1090.5725 0.77 30640 15723 2 1090.5732 546.2935 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3246.9 - 687303 - - - 0.6538 - 1.201 0.254 - 74.1 1 2 0 0.0007 9 0 0 0 4.60E+07 5.96E+07 - - - 1.4467 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.15736.15736.2 0.00597 14-Jul R.ELYPVEFR.N "sp|Q5BJF2|SGMR2_HUMAN,tr|J3KT68|J3KT68_HUMAN" 2 1051.5338 0.94 30649 15736 2 1051.53286 526.7742 Sigma intracellular receptor 2 OS=Homo sapiens OX=9606 GN=TMEM97 PE=1 SV=1 4.53 3248.4 - 599460 - - - -0.9377 - 1.454 0.443 - 220.9 1 2 0 -0.001 8 0 0 0 1.61E+07 1.70E+07 - - - 3.4416 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.15738.15738.2 0.0127 14-Sep R.TLEVYLVR.M sp|Q9Y4E8|UBP15_HUMAN 1 991.5702 1.25 30651 15738 2 991.568459 496.7924 Ubiquitin carboxyl-terminal hydrolase 15 OS=Homo sapiens OX=9606 GN=USP15 PE=1 SV=3 5.66 3248.7 - 1.46E+06 - - - -1.7881 - 1.845 0.326 - 299.3 1 2 0 -0.0018 8 0 0 0 1.92E+07 1.54E+07 - - - 3.2955 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.15744.15744.2 0.088 16-Oct K.EALEAVLIK.G "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 984.5855 1.62 30655 15744 2 984.585213 493.3001 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 4.53 3249.5 - 458404 - - - -0.3402 - 1.612 0.201 - 197.7 1 2 0 -0.0003 9 0 0 0 2.14E+07 1.32E+07 - - - 1.9068 0.9934 230117_WJC_METTL3_WT_vs_EV_F04.15746.15746.2 0.171 14-May K.EMVELPLR[166.11].H "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN" 10 995.5349 0.6 30657 15746 2 995.537197 498.7747 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.53 3249.7 - 479552 - - - 2.2842 - 1.193 0.183 - 77.7 1 2 0 0.0023 8 0 0 0 1.17E+07 1.95E+07 - - - 0.9242 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.15756.15756.2 0.0405 16-Sep R.ILPQDVILK[136.11].F "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1045.6627 0.96 30662 15756 2 1045.663075 523.8386 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.84 3251 - 599447 - - - 0.3758 - 1.489 0.319 - 158 1 2 0 0.0004 9 0 0 0 2.40E+07 2.49E+07 - - - 2.5487 0.9951 230117_WJC_METTL3_WT_vs_EV_F04.15757.15757.2 0.806 14-Jun K.EMVELPLR.H "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN" 10 985.5267 0.6 30663 15757 2 985.526651 493.7706 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.53 3251.1 - 470445 - - - -0.002 - 1.338 0.185 - 94 1 2 0 0 8 0 0 0 1.15E+07 1.94E+07 - - - 1.2856 1 230117_WJC_METTL3_WT_vs_EV_F04.15760.15760.2 0.000134 20-Nov R.LFSGDVVLTAR.D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1176.6503 0.98 30664 15760 2 1176.651047 589.3324 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3251.5 - 3.95E+06 - - - 0.6578 - 2.287 0.573 - 393.8 1 2 0 0.0008 11 0 0 0 1.98E+08 2.01E+08 - - - 5.5108 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.15761.15761.2 0.00432 18-Oct R.GLIENPALLR[166.11].W sp|O95168|NDUB4_HUMAN 1 1104.6531 1.27 30665 15761 2 1104.653413 553.3338 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3 6 3251.6 - 515575 - - - 0.3159 - 2.138 0.337 - 279.8 1 2 0 0.0003 10 0 0 0 3.51E+07 2.75E+07 - - - 3.651 0.9963 230117_WJC_METTL3_WT_vs_EV_F04.15762.15762.2 0.478 18-Sep K.ATLLLESGIR.L "sp|O60524|NEMF_HUMAN,tr|G3V547|G3V547_HUMAN,tr|G3V5V3|G3V5V3_HUMAN,tr|G3V4D9|G3V4D9_HUMAN" 4 1071.6288 1.32 30666 15762 2 1071.631343 536.8217 Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4 6.05 3251.8 - 250249 - - - 2.3646 - 1.53 0.16 - 154.2 1 2 0 0.0025 10 0 0 0 8.21E+06 6.22E+06 - - - 1.409 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.15765.15765.3 3.07E-07 15/64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 23.27 30667 15765 3 1786.984025 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3252.2 - 260229 - - - 0.6296 - 3.074 0.453 - 252.2 1 2 0 0.0011 17 0 0 0 3.85E+07 1.66E+06 - - - 6.4272 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.15767.15767.2 0.0398 22-Aug K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.22 30669 15767 2 1277.750984 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3252.4 - 223182 - - - 1.0886 - 1.5 0.23 - 100.5 2 2 0 0.0014 12 0 0 0 1.70E+07 1.39E+07 - - - 1.6717 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.15772.15772.2 0.537 14-Aug K.TAVLTLIR[166.11].E "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 8 895.573 1.24 30672 15772 2 895.573771 448.7938 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 9.41 3252.9 - 2.74E+06 - - - 0.8352 - 1.384 0.182 - 174.2 1 2 0 0.0007 8 0 0 0 1.32E+08 1.06E+08 - - - 1.3651 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.15773.15773.2 0.00367 16-Aug R.ILPQDVILK.F "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1037.6485 0.96 30673 15773 2 1037.650303 519.8315 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.84 3253 - 922691 - - - 1.7549 - 1.428 0.242 - 139.7 1 2 0 0.0018 9 0 0 0 2.40E+07 2.49E+07 - - - 1.8586 0.984 230117_WJC_METTL3_WT_vs_EV_F04.15774.15774.2 3.53 12-Jun R.AVLNLLR.R sp|Q93008|USP9X_HUMAN 1 797.5123 1.56 30674 15774 2 797.513966 399.7634 Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X PE=1 SV=4 9.79 3253.1 - 532387 - - - 2.0602 - 1.401 0.017 - 111.3 1 2 0 0.0016 7 0 0 0 1.44E+07 9.18E+06 - - - 0.2344 0.9943 230117_WJC_METTL3_WT_vs_EV_F04.15779.15779.2 0.924 12-Aug R.VLAAFLR.R "sp|Q9HB09|B2L12_HUMAN,sp|Q99607|ELF4_HUMAN,tr|M0R1Z8|M0R1Z8_HUMAN,tr|A0A087WU18|A0A087WU18_HUMAN,tr|I6LJZ9|I6LJZ9_HUMAN,tr|A0A087WSV0|A0A087WSV0_HUMAN,tr|I6LK00|I6LK00_HUMAN,tr|I6LJZ7|I6LJZ7_HUMAN,tr|M0R1K0|M0R1K0_HUMAN,tr|M0QZM6|M0QZM6_HUMAN" 10 788.4909 3.3 30677 15779 2 788.490382 395.2527 Bcl-2-like protein 12 OS=Homo sapiens OX=9606 GN=BCL2L12 PE=1 SV=1 9.72 3253.8 - 697403 - - - -0.605 - 1.709 0.097 - 208.2 1 2 0 -0.0005 7 0 0 0 2.42E+07 7.34E+06 - - - 1.4553 0.9451 230117_WJC_METTL3_WT_vs_EV_F04.15780.15780.2 5.42 12-Jun R.AVLNLLR[166.11].R sp|Q93008|USP9X_HUMAN 1 807.5206 1.5 30678 15780 2 807.522039 404.7676 Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X PE=1 SV=4 9.79 3253.9 - 406523 - - - 1.7907 - 1.156 0.001 - 107.5 2 2 0 0.0014 7 0 0 0 1.35E+07 9.01E+06 - - - -0.6272 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.15782.15782.3 0.000152 Oct-64 R.IINEPTAAAIAYGLDK[136.11]K[136.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1803.0113 23.27 30680 15782 3 1803.013559 602.011 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3254.1 - 113570 - - - 1.2529 - 2.236 0.434 - 72.4 1 2 0 0.0023 17 0 0 0 3.85E+07 1.66E+06 - - - 5.4109 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.15785.15785.2 0.337 12-Aug K.SIELFYK[136.11].F sp|P78527|PRKDC_HUMAN 1 906.4942 1.58 30681 15785 2 906.495478 454.2544 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.72 3254.5 - 1.17E+06 - - - 1.3878 - 1.242 0.175 - 209.6 1 2 0 0.0013 7 0 0 0 7.15E+07 4.52E+07 - - - 1.0199 0.9905 230117_WJC_METTL3_WT_vs_EV_F04.15786.15786.2 0.828 14-Jun K.FVIPLHSA.- sp|Q96F86|EDC3_HUMAN 1 882.4963 - 30682 15786 2 882.498475 442.2554 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 6.74 3254.7 - 1.23E+06 - - - 2.4204 - 1.161 0.165 - 125.2 1 2 0 0.0021 8 0 0 0 - - - - - 0.7092 0.9626 230117_WJC_METTL3_WT_vs_EV_F04.15788.15788.2 7.45 14-Jun K.GLVAVGER[166.11].A "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 3 809.4635 1.34 30684 15788 2 809.46479 405.739 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3254.9 - 511929 - - - 1.6282 - 1.215 0.015 - 79.7 2 2 0 0.0013 8 0 0 0 1.51E+07 1.12E+07 - - - -0.3958 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.15789.15789.2 0.137 20-Sep K.ALILVGGYGTR.L "sp|Q9Y5P6|GMPPB_HUMAN,tr|A0A7I2V691|A0A7I2V691_HUMAN,tr|A0A7I2V2Y5|A0A7I2V2Y5_HUMAN,tr|A0A7I2YQI5|A0A7I2YQI5_HUMAN,tr|A0A7I2V4B5|A0A7I2V4B5_HUMAN" 5 1118.6448 0.44 30685 15789 2 1118.647797 560.3297 Mannose-1-phosphate guanyltransferase beta OS=Homo sapiens OX=9606 GN=GMPPB PE=1 SV=2 8.79 3255.1 - 376638 - - - 2.6845 - 2.019 0.211 - 224.1 1 2 0 0.003 11 0 0 0 7.62E+06 1.74E+07 - - - 2.4992 0.9203 230117_WJC_METTL3_WT_vs_EV_F04.15794.15794.2 1.12 12-Jun K.SIELFYK.F sp|P78527|PRKDC_HUMAN 1 898.48 0.9 30688 15794 2 898.48185 450.2473 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.72 3255.8 - 1.17E+06 - - - 2.0368 - 0.881 0.072 - 106.2 1 2 0 0.0018 7 0 0 0 8.42E+07 9.41E+07 - - - -0.8292 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.15804.15804.2 0.473 12-Jun K.AFLFVNK.G sp|Q8N0X7|SPART_HUMAN 1 837.4749 1.44 30696 15804 2 837.476123 419.7447 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3257 - 7.22E+06 - - - 1.4902 - 1.154 0.234 - 170.9 1 2 0 0.0012 7 0 0 0 1.35E+08 9.35E+07 - - - 1.2228 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.15805.15805.2 0.0366 12-Jul K.AFLFVNK[136.11].G sp|Q8N0X7|SPART_HUMAN 1 845.4891 1.44 30697 15805 2 845.490068 423.7518 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3257 - 3.75E+06 - - - 1.1745 - 1.346 0.247 - 207.4 1 2 0 0.001 7 0 0 0 1.35E+08 9.35E+07 - - - 1.8065 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.15810.15810.2 0.00102 18-Sep K.VPVLISPTLK[136.11].H sp|P42684|ABL2_HUMAN 1 1073.694 2.6 30702 15810 2 1073.692014 537.8543 Tyrosine-protein kinase ABL2 OS=Homo sapiens OX=9606 GN=ABL2 PE=1 SV=1 8.72 3257.6 - 218837 - - - -1.8329 - 1.713 0.456 - 199.4 1 2 0 -0.002 10 0 0 0 1.05E+07 4.04E+06 - - - 3.9108 0.999 230117_WJC_METTL3_WT_vs_EV_F04.15814.15814.2 0.0584 16-Sep R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 0.74 30704 15814 2 960.611117 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3258.2 - 1.89E+07 - - - 1.2482 - 1.786 0.225 - 259.3 1 2 0 0.0012 9 0 0 0 1.05E+10 1.41E+10 - - - 2.3804 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.15815.15815.2 0.136 16-Jul R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 0.74 30705 15815 2 952.597066 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3258.2 - 1.07E+07 - - - 1.4151 - 1.288 0.184 - 160.7 1 2 0 0.0013 9 0 0 0 1.05E+10 1.41E+10 - - - 1.1318 0.9623 230117_WJC_METTL3_WT_vs_EV_F04.15817.15817.2 0.0041 18-Oct H.ILSPWGAEVK[136.11].A "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1106.6215 0.66 30707 15817 2 1106.622362 554.318 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3258.3 - 1.37E+06 - - - 0.7374 - 1.913 0.34 - 210.8 1 1 0 0.0008 10 0 0 0 6.16E+07 9.27E+07 - - - 3.3626 0.9623 230117_WJC_METTL3_WT_vs_EV_F04.15819.15819.2 0.00679 18-Nov H.ILSPWGAEVK.A "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1098.6073 0.7 30709 15819 2 1098.608282 550.3109 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3258.5 - 1.21E+06 - - - 0.852 - 1.983 0.321 - 367.6 1 1 0 0.0009 10 0 0 0 6.03E+07 8.64E+07 - - - 3.3226 0.9495 230117_WJC_METTL3_WT_vs_EV_F04.15825.15825.2 16.3 12-Jun R.SVINLLR.N "sp|Q96AT9|RPE_HUMAN,sp|Q2QD12|RPEL1_HUMAN,tr|C9J6A7|C9J6A7_HUMAN" 3 813.5072 1.78 30715 15825 2 813.509385 407.7609 Ribulose-phosphate 3-epimerase OS=Homo sapiens OX=9606 GN=RPE PE=1 SV=1 9.47 3259.1 - 463469 - - - 2.6392 - 1.204 0.002 - 110.6 1 2 0 0.0021 7 0 0 0 1.31E+07 7.38E+06 - - - -0.3567 0.9967 230117_WJC_METTL3_WT_vs_EV_F04.15826.15826.2 0.048 20-Aug K.FSPAGPVLSIR.V "sp|Q13310|PABP4_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN" 4 1142.6448 2.09 30716 15826 2 1142.649092 572.3297 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.75 3259.2 - 450700 - - - 3.7614 - 1.499 0.292 - 160.2 1 2 0 0.0043 11 0 0 0 1.16E+07 5.55E+06 - - - 2.2914 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.15833.15833.2 0.00163 18-Sep K.IGDLGLATLK.R "sp|Q9H4A3|WNK1_HUMAN,sp|Q96J92|WNK4_HUMAN,sp|Q9Y3S1|WNK2_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A6PVV2|A6PVV2_HUMAN,tr|K7ENT7|K7ENT7_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 9 999.5964 1.89 30721 15833 2 999.599024 500.8055 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 5.84 3260.1 - 2.18E+06 - - - 2.578 - 1.887 0.374 - 146.7 1 2 0 0.0026 10 0 0 0 8.54E+07 4.51E+07 - - - 3.575 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.15836.15836.2 0.00253 14-Jul K.YFEYIMAK[136.11].E sp|P13674|P4HA1_HUMAN 1 1071.5191 2.71 30724 15836 2 1071.52212 536.7668 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3260.4 - 589046 - - - 2.8614 - 1.241 0.324 - 117.6 1 2 0 0.0031 8 0 0 0 4.20E+07 1.55E+07 - - - 2.0843 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.15837.15837.2 0.0249 18-Sep R.LGFVAGVINR[166.11].E "sp|Q93050|VPP1_HUMAN,tr|K7EN36|K7EN36_HUMAN,tr|K7EPG4|K7EPG4_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 5 1054.6163 1.77 30725 15837 2 1054.615859 528.3154 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 9.75 3260.5 - 497208 - - - -0.403 - 1.7 0.266 - 201.5 1 2 0 -0.0004 10 0 0 0 2.29E+07 1.29E+07 - - - 2.4867 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.15842.15842.2 0.156 14-Aug K.YFEYIMAK.E sp|P13674|P4HA1_HUMAN 1 1063.5049 2.73 30727 15842 2 1063.50446 532.7597 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3261.1 - 1.33E+06 - - - -0.3705 - 1.543 0.295 - 173 1 2 0 -0.0004 8 0 0 0 4.22E+07 1.55E+07 - - - 2.5279 0.9905 230117_WJC_METTL3_WT_vs_EV_F04.15849.15849.2 0.75 12-Aug R.VLQLFTR[166.11].L "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 885.5312 1 30732 15849 2 885.530376 443.7729 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 9.72 3262.1 - 2.27E+06 - - - -0.8831 - 1.419 0.14 - 200 1 2 0 -0.0008 7 0 0 0 3.61E+07 3.59E+07 - - - 1.1836 0.9068 230117_WJC_METTL3_WT_vs_EV_F04.15854.15854.2 0.305 16-Jun K.KDIFNEHLR[166.11].L "sp|O14686|KMT2D_HUMAN,tr|A0A804HHR9|A0A804HHR9_HUMAN" 2 1180.6228 - 30734 15854 2 1180.619239 591.3187 Histone-lysine N-methyltransferase 2D OS=Homo sapiens OX=9606 GN=KMT2D PE=1 SV=2 6.75 3262.7 - 0 - - - -3.0382 - 1.391 0.062 - 103.7 1 2 0 -0.0036 9 0 0 0 - - - - - 0.4526 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.15856.15856.2 0.000252 16-Sep K.VLPVGVLYK.V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 986.6165 0.56 30736 15856 2 986.615609 494.3155 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3263 - 346066 - - - -0.8565 - 1.471 0.42 - 164.1 1 2 0 -0.0008 9 0 0 0 1.07E+08 1.93E+08 - - - 3.2594 0.8898 230117_WJC_METTL3_WT_vs_EV_F04.15862.15862.2 0.0431 14-Aug K.GIAYIEFK[136.11].T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 947.5208 0.84 30739 15862 2 947.51555 474.7677 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3263.7 - 5.27E+06 - - - -5.5081 - 1.343 0.209 - 180.3 1 2 0 -0.0052 8 0 0 0 5.96E+08 7.08E+08 - - - 1.4725 0.9565 230117_WJC_METTL3_WT_vs_EV_F04.15863.15863.2 2.07 12-Jun K.ILIWSGR.F "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 843.4967 1.55 30740 15863 2 843.496805 422.7556 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 9.75 3263.8 - 669557 - - - 0.1565 - 1.276 0.001 - 122.3 2 2 0 0.0001 7 0 0 0 8.44E+07 5.46E+07 - - - -0.3139 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.15869.15869.2 0.000214 20-Nov R.ILMVGLDAAGK.T "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|F5H1V1|F5H1V1_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|F5H6T5|F5H6T5_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|F8WDB3|F8WDB3_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 11 1086.6107 1.83 30744 15869 2 1086.61165 544.3126 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3264.5 - 1.88E+06 - - - 0.8586 - 2.235 0.433 - 332.9 1 2 0 0.0009 11 0 0 0 2.61E+08 1.42E+08 - - - 4.4145 0.9952 230117_WJC_METTL3_WT_vs_EV_F04.15875.15875.2 0.554 12-Jul K.ILIWSGR[166.11].F "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 853.5049 1.54 30748 15875 2 853.505215 427.7597 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 9.75 3265.2 - 1.29E+06 - - - 0.3187 - 1.449 0.132 - 149.7 1 2 0 0.0003 7 0 0 0 8.38E+07 5.45E+07 - - - 1.191 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.15877.15877.2 4.50E-05 16-Sep R.VFNPYTEFK.E sp|Q96C19|EFHD2_HUMAN 1 1143.5601 1.74 30750 15877 2 1143.560368 572.7873 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 5.97 3265.4 - 934064 - - - 0.2685 - 1.73 0.448 - 207.9 1 2 0 0.0003 9 0 0 0 1.81E+07 1.04E+07 - - - 3.9356 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.15878.15878.3 9.06E-05 13/36 R.ILIAKPIMFR.G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1200.7417 1.99 30751 15878 3 1200.740958 401.2545 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3265.5 - 495282 - - - -0.5938 - 1.893 0.41 - 173.1 1 2 0 -0.0007 10 0 0 0 1.65E+08 8.29E+07 - - - 4.9746 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.15896.15896.2 0.000477 20-Dec R.ILMVGLDAAGK[136.11].T "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|F5H1V1|F5H1V1_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|F5H6T5|F5H6T5_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|F8WDB3|F8WDB3_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 11 1094.6249 1.83 30763 15896 2 1094.623212 548.3197 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3267.6 - 4.47E+06 - - - -1.5576 - 2.335 0.397 - 429.9 1 2 0 -0.0017 11 0 0 0 2.61E+08 1.43E+08 - - - 4.2668 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.15899.15899.2 0.0474 16-Aug R.LLLQLEATK.N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1027.6277 8.16 30766 15899 2 1027.627537 514.8211 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3267.8 - 1.24E+06 - - - -0.2044 - 1.852 0.198 - 162.4 1 2 0 -0.0002 9 0 0 0 5.92E+08 7.26E+07 - - - 2.2863 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.15901.15901.3 0.00288 Dec-36 R.ILIAKPIMFR.G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1200.7417 1.99 30768 15901 3 1200.742233 401.2545 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3268.1 - 575930 - - - 0.468 - 1.795 0.368 - 131.9 1 2 0 0.0006 10 0 0 0 1.65E+08 8.29E+07 - - - 4.3511 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.15903.15903.2 0.00892 14-Sep K.GIAYIEFK.T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 939.5066 0.84 30769 15903 2 939.507392 470.7606 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3268.3 - 2.46E+07 - - - 0.876 - 1.782 0.148 - 263.8 1 2 0 0.0008 8 0 0 0 5.97E+08 7.08E+08 - - - 1.8763 0.9958 230117_WJC_METTL3_WT_vs_EV_F04.15905.15905.2 0.0463 18-Aug K.ILPEEITNLR.N sp|Q9H9A6|LRC40_HUMAN 1 1196.6765 0.88 30770 15905 2 1196.674316 599.3455 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3268.5 - 405448 - - - -1.815 - 1.516 0.306 - 200.4 1 2 0 -0.0022 10 0 0 0 3.72E+07 4.23E+07 - - - 2.4618 0.9706 230117_WJC_METTL3_WT_vs_EV_F04.15916.15916.2 3.5 12-May R.LFFVGSR[166.11].E "sp|Q9UM01|YLAT1_HUMAN,sp|Q92536|YLAT2_HUMAN,sp|Q01650|LAT1_HUMAN,tr|H0YJ95|H0YJ95_HUMAN,tr|A0A0C4DGL4|A0A0C4DGL4_HUMAN,tr|G3V4Z6|G3V4Z6_HUMAN" 6 834.4627 0.84 30777 15916 2 834.463839 418.2386 Y+L amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A7 PE=1 SV=2 9.75 3269.9 - 1.38E+06 - - - 1.3122 - 0.976 0.135 - 86.8 3 2 0 0.0011 7 0 0 0 2.18E+07 2.59E+07 - - - -0.2523 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.15920.15920.2 0.00221 16-Aug R.LLLQLEATK[136.11].N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1035.6419 7.68 30781 15920 2 1035.641994 518.8282 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3270.1 - 7.39E+06 - - - 0.0454 - 1.689 0.406 - 171 1 2 0 0 9 0 0 0 5.93E+08 7.72E+07 - - - 3.5561 1 230117_WJC_METTL3_WT_vs_EV_F04.15922.15922.2 3.69E-06 16-Oct R.MNVLADALK.S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 973.5267 1.33 30783 15922 2 973.524537 487.7706 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3270.3 - 3.06E+06 - - - -2.1735 - 2.169 0.451 - 330.5 1 2 0 -0.0021 9 0 0 0 4.45E+08 3.35E+08 - - - 4.6114 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.15923.15923.2 0.000311 16-Sep R.MNVLADALK[136.11].S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 981.5409 1.33 30784 15923 2 981.539852 491.7777 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3270.4 - 3.04E+06 - - - -1.0198 - 2.108 0.449 - 276 1 2 0 -0.001 9 0 0 0 4.45E+08 3.35E+08 - - - 4.5145 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.15926.15926.3 0.00024 Oct-36 R.ILIAK[136.11]PIMFR[166.11].G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1218.7641 2.22 30787 15926 3 1218.761974 407.262 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3270.6 - 2.16E+06 - - - -1.778 - 1.985 0.44 - 86.8 1 2 0 -0.0022 10 0 0 0 1.55E+08 6.99E+07 - - - 5.4473 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.15932.15932.2 0.024 14-Oct R.TAYLLYYR[166.11].R sp|Q14694|UBP10_HUMAN 1 1071.5629 0.94 30791 15932 2 1071.56167 536.7887 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.16 3271.3 - 828866 - - - -1.1031 - 1.621 0.368 - 286 1 2 0 -0.0012 8 0 0 0 3.19E+07 3.39E+07 - - - 3.2155 0.9515 230117_WJC_METTL3_WT_vs_EV_F04.15936.15936.2 0.597 12-Jul R.LYDGLFK[136.11].V "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 10 862.468 1.84 30793 15936 2 862.466779 432.2413 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.83 3271.9 - 5.75E+06 - - - -1.4215 - 1.258 0.063 - 104.5 1 2 0 -0.0012 7 0 0 0 1.88E+08 1.02E+08 - - - 0.2332 0.9945 230117_WJC_METTL3_WT_vs_EV_F04.15937.15937.2 3.02 12-Jul K.ILIEDWK[136.11].K "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A7I2V2T6|A0A7I2V2T6_HUMAN,tr|K7EPW7|K7EPW7_HUMAN" 4 923.5208 1.22 30794 15937 2 923.52299 462.7677 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 4.37 3271.9 - 1.34E+06 - - - 2.4049 - 1.378 0.142 - 152.2 1 2 0 0.0022 7 0 0 0 3.22E+07 2.64E+07 - - - 1.1051 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.15939.15939.2 0.0654 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.13 30796 15939 2 1235.760316 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3272.2 - 626955 - - - 0.1279 - 1.807 0.297 - 263.2 1 2 0 0.0002 11 0 0 0 3.41E+08 3.02E+08 - - - 2.8352 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.15940.15940.2 6.97E-05 18-Sep R.GYFEYIEENK.Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1290.5768 1.44 30797 15940 2 1290.576205 646.2957 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3272.3 - 414207 - - - -0.4866 - 1.902 0.478 - 151 1 2 0 -0.0006 10 0 0 0 7.17E+06 4.99E+06 - - - 4.3659 0.999 230117_WJC_METTL3_WT_vs_EV_F04.15946.15946.2 0.000258 16-Sep K.VLPVGVLYK[136.11].V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 994.6307 0.56 30801 15946 2 994.63008 498.3226 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3273 - 3.44E+06 - - - -0.5771 - 1.759 0.353 - 279.4 1 2 0 -0.0006 9 0 0 0 1.07E+08 1.93E+08 - - - 3.2819 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.15949.15949.2 0.254 20-Sep K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.13 30802 15949 2 1245.769941 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3273.4 - 1.06E+06 - - - 1.2145 - 1.546 0.215 - 104.8 1 2 0 0.0015 11 0 0 0 3.41E+08 3.02E+08 - - - 1.8071 1 230117_WJC_METTL3_WT_vs_EV_F04.15950.15950.2 0.000218 20-Dec R.LVDAVLGAEIR[166.11].N "sp|Q9UBN7|HDAC6_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8Y758|A0A2R8Y758_HUMAN,tr|A0A2R8Y559|A0A2R8Y559_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 5 1164.6742 0.87 30803 15950 2 1164.677059 583.3444 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.37 3273.5 - 176844 - - - 2.4608 - 2.357 0.445 - 336.3 1 2 0 0.0029 11 0 0 0 3.66E+07 4.19E+07 - - - 4.6463 0.9911 230117_WJC_METTL3_WT_vs_EV_F04.15952.15952.2 0.294 16-Jun K.VIIDTLITK[136.11].L sp|O15164|TIF1A_HUMAN 1 1022.6467 1.21 30805 15952 2 1022.64861 512.3306 Transcription intermediary factor 1-alpha OS=Homo sapiens OX=9606 GN=TRIM24 PE=1 SV=3 5.81 3273.8 - 194142 - - - 1.8697 - 1.295 0.128 - 57.3 2 2 0 0.0019 9 0 0 0 1.16E+07 9.57E+06 - - - 0.5992 0.9549 230117_WJC_METTL3_WT_vs_EV_F04.15964.15964.2 1.28 14-Jul K.AVWLPAVK.A "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 882.5327 1.36 30813 15964 2 882.536792 442.2736 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.8 3275.2 - 552951 - - - 4.6095 - 1.231 0.122 - 187.1 1 2 0 0.0041 8 0 0 0 3.14E+07 2.32E+07 - - - 0.5676 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.15965.15965.2 8.91E-05 16-Aug K.VIVPNMEFR.A sp|P55060|XPO2_HUMAN 1 1103.5798 1.32 30814 15965 2 1103.58115 552.7972 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.97 3275.3 - 447406 - - - 1.2677 - 1.824 0.477 - 271.2 1 2 0 0.0014 9 0 0 0 1.13E+08 8.57E+07 - - - 4.3025 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.15966.15966.2 0.000273 18-Sep K.ILPEEITNLR[166.11].N sp|Q9H9A6|LRC40_HUMAN 1 1206.6848 0.87 30815 15966 2 1206.685202 604.3497 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3275.4 - 352004 - - - 0.368 - 1.78 0.408 - 314.2 1 2 0 0.0004 10 0 0 0 3.72E+07 4.28E+07 - - - 3.6639 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.15969.15969.2 0.0522 14-Aug K.AVWLPAVK[136.11].A "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 890.5469 1.5 30816 15969 2 890.547593 446.2807 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.8 3275.8 - 819843 - - - 0.7512 - 1.454 0.273 - 226 1 2 0 0.0007 8 0 0 0 3.14E+07 2.10E+07 - - - 2.1861 1 230117_WJC_METTL3_WT_vs_EV_F04.15970.15970.2 4.63E-06 13/20 R.LVDAVLGAEIR.N "sp|Q9UBN7|HDAC6_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8Y758|A0A2R8Y758_HUMAN,tr|A0A2R8Y559|A0A2R8Y559_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 5 1154.6659 0.87 30817 15970 2 1154.669187 578.3402 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.37 3276 - 1.18E+06 - - - 2.8268 - 2.51 0.502 - 653.9 1 2 0 0.0033 11 0 0 0 3.64E+07 4.19E+07 - - - 5.2373 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.15971.15971.2 0.0447 14-Oct R.TLINELVK[136.11].G "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 7 936.5735 1.56 30818 15971 2 936.574586 469.294 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.66 3276 - 5.49E+06 - - - 1.1243 - 1.666 0.36 - 274 1 2 0 0.0011 8 0 0 0 1.04E+08 6.65E+07 - - - 3.239 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.15979.15979.2 0.0177 18-Sep R.VPFLVAETPR.A sp|Q13131|AAPK1_HUMAN 1 1127.6339 8.21 30824 15979 2 1127.633641 564.8242 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4 5.97 3277 - 533020 - - - -0.2253 - 1.745 0.336 - 227 1 2 0 -0.0003 10 0 0 0 1.08E+07 1.31E+06 - - - 3.0767 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.15980.15980.2 0.00297 14-Aug K.LLFVPC[160.03]SR[166.11].V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 1000.5403 0.84 30825 15980 2 1000.539679 501.2774 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.25 3277.1 - 2.47E+06 - - - -0.6626 - 1.722 0.285 - 207.2 1 2 0 -0.0007 8 0 0 0 3.10E+07 3.67E+07 - - - 2.7849 0.9843 230117_WJC_METTL3_WT_vs_EV_F04.15981.15981.2 0.088 16-Aug K.IYPVGYFTK.E "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 1086.575 9.33 30826 15981 2 1086.57393 544.2948 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.5 3277.2 - 1.59E+06 - - - -0.9691 - 1.271 0.15 - 171.3 1 2 0 -0.0011 9 0 0 0 5.88E+07 6.31E+06 - - - 0.8423 1 230117_WJC_METTL3_WT_vs_EV_F04.15983.15983.2 8.13E-06 18-Nov K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 7.9 30828 15983 2 1149.581575 575.7982 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3277.4 - 337756 - - - -0.247 - 2.302 0.505 - 484.1 1 2 0 -0.0003 10 0 0 0 9.26E+08 1.17E+08 - - - 5.0982 0.9903 230117_WJC_METTL3_WT_vs_EV_F04.15987.15987.2 0.266 14-Jul K.LIELLAGK[136.11].A sp|Q9NW08|RPC2_HUMAN 1 863.5572 0.99 30830 15987 2 863.557439 432.7859 DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2 6 3278 - 306243 - - - 0.33 - 1.419 0.075 - 104.2 1 2 0 0.0003 8 0 0 0 1.05E+07 1.06E+07 - - - 0.6503 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.15988.15988.2 0.00453 18-Sep R.TVPLLLAESK[136.11].F sp|Q709C8|VP13C_HUMAN 1 1077.6525 0.83 30831 15988 2 1077.651626 539.8335 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 5.66 3278.1 - 369488 - - - -0.8212 - 1.53 0.347 - 214.9 1 2 0 -0.0009 10 0 0 0 6.29E+06 7.58E+06 - - - 2.7907 1 230117_WJC_METTL3_WT_vs_EV_F04.15996.15996.2 0.0107 18-Nov K.FAEAFEAIPR[166.11].A sp|P50990|TCPQ_HUMAN 1 1159.5901 8.43 30837 15996 2 1159.589781 580.8023 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3279.1 - 380370 - - - -0.3001 - 2.299 0.502 - 409.7 1 2 0 -0.0003 10 0 0 0 9.18E+08 1.09E+08 - - - 5.0724 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.16002.16002.2 0.023 12-Jul R.EEYLLLR.L "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 934.5124 1.51 30841 16002 2 934.51488 468.2635 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.53 3279.9 - 918207 - - - 2.672 - 1.409 0.298 - 248.6 1 2 0 0.0025 7 0 0 0 4.44E+07 2.95E+07 - - - 2.3277 0.9938 230117_WJC_METTL3_WT_vs_EV_F04.16003.16003.2 0.544 14-Jul K.LLFVPC[160.03]SR.V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 990.5321 0.85 30842 16003 2 990.534366 496.2733 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.25 3280 - 647430 - - - 2.3159 - 1.265 0.168 - 118.9 1 2 0 0.0023 8 0 0 0 3.12E+07 3.67E+07 - - - 0.9901 0.9904 230117_WJC_METTL3_WT_vs_EV_F04.16004.16004.2 0.327 12-May R.EEYLLLR[166.11].L "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 944.5207 1.63 30843 16004 2 944.518878 473.2676 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.53 3280.1 - 584397 - - - -1.8793 - 1.236 0.27 - 102.6 1 2 0 -0.0018 7 0 0 0 4.25E+07 2.60E+07 - - - 1.706 0.9922 230117_WJC_METTL3_WT_vs_EV_F04.16005.16005.2 0.0117 14-Jun R.WLPEEDFR.R sp|Q8IXT5|RB12B_HUMAN 1 1090.5084 1.61 30844 16005 2 1090.511745 546.2615 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 4.14 3280.2 - 235431 - - - 3.1041 - 1.257 0.192 - 95.6 1 2 0 0.0034 8 0 0 0 1.17E+07 7.27E+06 - - - 1.1479 0.892 230117_WJC_METTL3_WT_vs_EV_F04.16016.16016.2 0.516 12-Aug S.LIQLLGR.N "sp|Q9P035|HACD3_HUMAN,sp|P82930|RT34_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN,tr|C9JJ19|C9JJ19_HUMAN,tr|H3BMZ1|H3BMZ1_HUMAN,tr|H3BRL8|H3BRL8_HUMAN" 7 811.528 1.14 30851 16016 2 811.529495 406.7713 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 9.75 3281.5 - 1.95E+06 - - - 1.8755 - 1.682 0.182 - 190.8 1 1 0 0.0015 7 0 0 0 5.17E+08 4.54E+08 - - - 2.0324 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.16018.16018.2 0.0331 24-Aug K.LGPGAGAGFGVLR.R "sp|Q9BUL5|PHF23_HUMAN,tr|I3L1N0|I3L1N0_HUMAN,tr|I3L410|I3L410_HUMAN,tr|I3L4Q4|I3L4Q4_HUMAN" 4 1170.6509 6.82 30853 16018 2 1170.652373 586.3327 PHD finger protein 23 OS=Homo sapiens OX=9606 GN=PHF23 PE=1 SV=1 9.75 3281.7 - 428563 - - - 1.2224 - 1.759 0.27 - 93.5 1 2 0 0.0014 13 0 0 0 2.00E+07 2.94E+06 - - - 2.4842 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.16019.16019.2 0.00152 16-Jul R.EPLSLINVR[166.11].K sp|Q96HS1|PGAM5_HUMAN 1 1049.6109 0.01 30854 16019 2 1049.610039 525.8127 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 6.1 3281.8 - 425263 - - - -0.787 - 1.593 0.329 - 125.5 1 2 0 -0.0008 9 0 0 0 7.36E+04 1.41E+07 - - - 2.8178 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.16023.16023.2 1.12E-05 14-Sep K.FC[160.03]ELLIGR.G "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1006.527 999 30856 16023 2 1006.528334 504.2708 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.99 3282.3 - 795962 - - - 1.3383 - 1.861 0.472 - 325.6 1 2 0 0.0013 8 0 0 0 1.99E+08 0.00E+00 - - - 4.4 0.9777 230117_WJC_METTL3_WT_vs_EV_F04.16024.16024.2 0.906 12-May K.WPVAWGK.L "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 842.4439 1.09 30857 16024 2 842.444331 422.2292 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.75 3282.4 - 310398 - - - 0.5009 - 1.022 0.125 - 56.2 1 2 0 0.0004 7 0 0 0 7.73E+06 7.11E+06 - - - 0.0331 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.16037.16037.2 0.0248 14-Jul K.ELPTVVFR.A sp|Q9BVP2|GNL3_HUMAN 1 959.544 0.94 30866 16037 2 959.546969 480.7793 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 6.1 3284 - 4.55E+06 - - - 3.0765 - 1.32 0.354 - 198.9 1 2 0 0.003 8 0 0 0 1.23E+08 1.31E+08 - - - 2.492 0.9936 230117_WJC_METTL3_WT_vs_EV_F04.16040.16040.2 0.205 12-Jul K.VFGIQLK.E "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN" 3 803.4905 8.04 30867 16040 2 803.49255 402.7525 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 8.72 3284.4 - 1.98E+06 - - - 2.5203 - 1.232 0.181 - 146.7 1 2 0 0.002 7 0 0 0 7.72E+07 9.61E+06 - - - 1.0383 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.16042.16042.2 0.0349 14-Jul K.ELPTVVFR[166.11].A sp|Q9BVP2|GNL3_HUMAN 1 969.5523 0.93 30869 16042 2 969.554302 485.7834 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 6.1 3284.6 - 3.76E+06 - - - 2.0783 - 1.468 0.379 - 219.6 1 2 0 0.002 8 0 0 0 1.23E+08 1.32E+08 - - - 2.9975 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.16050.16050.2 0.00582 16-Aug K.VYEAVELLK.S sp|Q8TEQ6|GEMI5_HUMAN 1 1062.5961 0.81 30872 16050 2 1062.598455 532.3053 Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3 4.53 3285.8 - 1.34E+06 - - - 2.205 - 1.309 0.342 - 185.1 1 2 0 0.0023 9 0 0 0 2.48E+07 3.05E+07 - - - 2.3453 0.9771 230117_WJC_METTL3_WT_vs_EV_F04.16051.16051.2 1.27 14-Jun R.ILVIGLSR[166.11].E sp|Q8N201|INT1_HUMAN 1 879.5781 1.27 30873 16051 2 879.579973 440.7963 Integrator complex subunit 1 OS=Homo sapiens OX=9606 GN=INTS1 PE=1 SV=2 9.75 3286 - 406857 - - - 2.1203 - 1.351 0.037 - 76.6 3 2 0 0.0019 8 0 0 0 9.64E+06 7.62E+06 - - - 0.0079 0.999 230117_WJC_METTL3_WT_vs_EV_F04.16054.16054.2 0.0247 16-Aug K.VIVPNMEFR[166.11].A sp|P55060|XPO2_HUMAN 1 1113.588 1.32 30875 16054 2 1113.590906 557.8013 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.97 3286.3 - 716570 - - - 2.5907 - 1.57 0.328 - 215 1 2 0 0.0029 9 0 0 0 1.13E+08 8.57E+07 - - - 2.7677 0.995 230117_WJC_METTL3_WT_vs_EV_F04.16060.16060.2 0.00438 20-Nov K.LLLIGDSGVGK.T "sp|P61006|RAB8A_HUMAN,sp|P51153|RAB13_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P59190|RAB15_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YL94|H0YL94_HUMAN,tr|A0A2R8YDI9|A0A2R8YDI9_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|G3V196|G3V196_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H0YLJ8|H0YLJ8_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN,tr|F5H157|F5H157_HUMAN" 19 1070.6336 1.47 30878 16060 2 1070.639899 536.3241 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.84 3287.1 - 2.04E+06 - - - 5.9208 - 1.902 0.385 - 321.9 1 2 0 0.0063 11 0 0 0 4.42E+08 3.01E+08 - - - 3.6218 0.9969 230117_WJC_METTL3_WT_vs_EV_F04.16061.16061.2 0.929 14-Aug R.LLEGLSLR.D sp|Q8NEN9|PDZD8_HUMAN 1 899.544 1.33 30879 16061 2 899.546287 450.7793 PDZ domain-containing protein 8 OS=Homo sapiens OX=9606 GN=PDZD8 PE=1 SV=1 6 3287.2 - 918958 - - - 2.5235 - 1.469 0.194 - 147.6 1 2 0 0.0023 8 0 0 0 1.30E+07 9.74E+06 - - - 1.6331 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.16062.16062.2 1.55 14-Aug R.LLEGLSLR[166.11].D sp|Q8NEN9|PDZD8_HUMAN 1 909.5523 1.32 30880 16062 2 909.554015 455.7834 PDZ domain-containing protein 8 OS=Homo sapiens OX=9606 GN=PDZD8 PE=1 SV=1 6 3287.3 - 847966 - - - 1.8998 - 1.374 0.217 - 149.2 1 2 0 0.0017 8 0 0 0 1.29E+07 9.74E+06 - - - 1.6015 0.9833 230117_WJC_METTL3_WT_vs_EV_F04.16068.16068.2 0.232 12-Jun K.MIFVGIK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 806.4724 2.21 30884 16068 2 806.475542 404.2435 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 8.5 3288.1 - 356184 - - - 3.8563 - 1.231 0.167 - 155.2 1 2 0 0.0031 7 0 0 0 3.89E+07 1.76E+07 - - - 0.932 0.9024 230117_WJC_METTL3_WT_vs_EV_F04.16073.16073.2 0.36 16-Sep R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 0.74 30887 16073 2 960.605447 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3288.8 - 1.22E+06 - - - -4.6543 - 1.348 0.169 - 172.2 1 2 0 -0.0045 9 0 0 0 1.05E+10 1.41E+10 - - - 1.1518 0.9938 230117_WJC_METTL3_WT_vs_EV_F04.16075.16075.2 0.0267 16-Aug K.LYENLGFVR.D "sp|Q147X3|NAA30_HUMAN,tr|J3KNC2|J3KNC2_HUMAN,tr|B4DK34|B4DK34_HUMAN" 3 1109.5869 1.78 30888 16075 2 1109.590928 555.8007 N-alpha-acetyltransferase 30 OS=Homo sapiens OX=9606 GN=NAA30 PE=1 SV=1 6 3289 - 869228 - - - 3.5896 - 1.292 0.244 - 71.5 1 2 0 0.004 9 0 0 0 9.79E+06 5.50E+06 - - - 1.5831 0.8912 230117_WJC_METTL3_WT_vs_EV_F04.16086.16086.2 0.12 16-Jul K.LYENLGFVR[166.11].D "sp|Q147X3|NAA30_HUMAN,tr|J3KNC2|J3KNC2_HUMAN,tr|B4DK34|B4DK34_HUMAN" 3 1119.5952 1.85 30897 16086 2 1119.592718 560.8049 N-alpha-acetyltransferase 30 OS=Homo sapiens OX=9606 GN=NAA30 PE=1 SV=1 6 3290.4 - 93747.6 - - - -2.2303 - 1.297 0.028 - 100.9 1 2 0 -0.0025 9 0 0 0 9.62E+06 5.21E+06 - - - -0.0006 0.9611 230117_WJC_METTL3_WT_vs_EV_F04.16088.16088.2 3.47 12-Jun K.IIAALFK.A "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 774.5004 1.75 30899 16088 2 774.501875 388.2575 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3290.6 - 357075 - - - 1.9548 - 1.227 0.02 - 71.6 3 2 0 0.0015 7 0 0 0 3.34E+07 1.90E+07 - - - -0.3767 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.16091.16091.2 0.399 16-Sep K.LTLLQVASR.Q sp|O95239|KIF4A_HUMAN 1 999.6077 2.08 30900 16091 2 999.609996 500.8111 Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3 9.75 3291.1 - 1.59E+06 - - - 2.3169 - 1.82 0.21 - 251.6 1 2 0 0.0023 9 0 0 0 3.13E+07 1.51E+07 - - - 2.3238 0.9464 230117_WJC_METTL3_WT_vs_EV_F04.16092.16092.2 2.65 14-May R.LEEIPLIK.S sp|Q14152|EIF3A_HUMAN 1 953.5797 0.88 30901 16092 2 953.582679 477.7971 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 3291.1 - 1.27E+06 - - - 3.0884 - 1.331 0.055 - 55.5 16 2 0 0.0029 8 0 0 0 8.41E+07 9.51E+07 - - - -0.2292 0.9772 230117_WJC_METTL3_WT_vs_EV_F04.16095.16095.2 1.87 12-Apr K.IIAALFK[136.11].A "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 782.5146 1.79 30904 16095 2 782.515269 392.2646 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3291.5 - 386683 - - - 0.9048 - 1.122 0.109 - 41.3 4 2 0 0.0007 7 0 0 0 3.41E+07 1.90E+07 - - - -0.0583 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.16096.16096.2 0.0162 14-Aug R.LSYTQLLR.R "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 992.5655 7.21 30905 16096 2 992.566344 497.29 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.75 3291.6 - 324392 - - - 0.8695 - 1.812 0.371 - 157 1 2 0 0.0009 8 0 0 0 2.83E+07 3.93E+06 - - - 3.5737 0.9933 230117_WJC_METTL3_WT_vs_EV_F04.16101.16101.2 0.85 14-Jun K.LFIGNLPR.E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 928.5494 2.15 30909 16101 2 928.551224 465.282 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3292.2 - 3.19E+07 - - - 1.9245 - 1.189 0.169 - 155.7 1 2 0 0.0018 8 0 0 0 3.71E+09 1.73E+09 - - - 0.8108 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.16103.16103.2 1.33 12-Aug K.YGAFLLR.R "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 838.4701 1.15 30910 16103 2 838.47119 420.2423 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.75 3292.4 - 2.18E+06 - - - 1.2714 - 1.712 0.21 - 226.6 1 2 0 0.0011 7 0 0 0 3.55E+07 3.09E+07 - - - 2.2953 0.9925 230117_WJC_METTL3_WT_vs_EV_F04.16105.16105.2 0.314 14-Aug R.LISLPLSR[166.11].L "sp|Q9NRG0|CHRC1_HUMAN,tr|E5RGS9|E5RGS9_HUMAN" 2 907.573 1.74 30912 16105 2 907.575461 454.7938 Chromatin accessibility complex protein 1 OS=Homo sapiens OX=9606 GN=CHRAC1 PE=1 SV=1 9.75 3292.7 - 1.75E+06 - - - 2.6863 - 1.486 0.102 - 137.6 1 2 0 0.0024 8 0 0 0 9.35E+07 5.39E+07 - - - 0.9882 0.8944 230117_WJC_METTL3_WT_vs_EV_F04.16106.16106.2 0.122 14-Aug R.PLELSDFR.M "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 975.5025 1.73 30913 16106 2 975.504783 488.7585 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.37 3292.8 - 510929 - - - 2.2932 - 1.618 0.232 - 229.7 1 1 0 0.0022 8 0 0 0 5.85E+07 3.39E+07 - - - 2.2051 0.9949 230117_WJC_METTL3_WT_vs_EV_F04.16117.16117.2 2.46 14-Sep K.GGLGLILK.R "sp|O75832|PSD10_HUMAN,tr|B1AJY5|B1AJY5_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 3 769.5062 1.54 30919 16117 2 769.506904 385.7604 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 8.75 3294 - 926529 - - - 0.9474 - 1.401 0.126 - 196.1 1 2 0 0.0007 8 0 0 0 9.55E+07 6.18E+07 - - - 0.9883 0.99 230117_WJC_METTL3_WT_vs_EV_F04.16128.16128.2 0.0198 14-Aug R.GFVLYPVK.Y sp|P62487|RPB7_HUMAN 1 921.5324 0.01 30928 16128 2 921.536551 461.7735 DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1 8.59 3295.4 - 703937 - - - 4.5153 - 1.183 0.294 - 176.4 1 2 0 0.0042 8 0 0 0 2.03E+07 1.84E+09 - - - 1.718 0.9958 230117_WJC_METTL3_WT_vs_EV_F04.16134.16134.2 8.48 14-Sep K.GGLGLILK[136.11].R "sp|O75832|PSD10_HUMAN,tr|B1AJY5|B1AJY5_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 3 777.5204 1.54 30932 16134 2 777.521198 389.7675 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 8.75 3296.2 - 953866 - - - 1.0585 - 1.704 0.063 - 166.7 1 2 0 0.0008 8 0 0 0 9.54E+07 6.18E+07 - - - 1.1135 0.998 230117_WJC_METTL3_WT_vs_EV_F04.16136.16136.2 3.73 12-Sep R.LSAIFLR[166.11].L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 828.5097 1.63 30934 16136 2 828.511125 415.2621 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3296.5 - 260860 - - - 1.7272 - 1.909 0.089 - 228.9 1 2 0 0.0014 7 0 0 0 5.33E+07 3.27E+07 - - - 1.7466 0.9949 230117_WJC_METTL3_WT_vs_EV_F04.16137.16137.2 0.0621 12-May R.EYFYGFR.G "sp|Q92989|CLP1_HUMAN,tr|E9PL17|E9PL17_HUMAN" 2 980.4392 3.09 30935 16137 2 980.440392 491.2269 Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1 6.1 3296.6 - 219087 - - - 1.1974 - 1.125 0.21 - 69.6 1 2 0 0.0012 7 0 0 0 5.87E+06 1.90E+06 - - - 0.9649 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.16138.16138.2 0.000475 18-Oct K.AMTILLEEAK.A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1117.6053 1.94 30936 16138 2 1117.606969 559.8099 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3296.7 - 172451 - - - 1.4961 - 2.143 0.316 - 333.9 1 2 0 0.0017 10 0 0 0 4.35E+07 2.24E+07 - - - 3.502 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.16145.16145.2 1.2 12-Jul R.LSAIFLR.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 818.5014 1.56 30941 16145 2 818.502066 410.258 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3297.4 - 1.73E+06 - - - 0.7844 - 1.684 0.093 - 167.9 1 2 0 0.0006 7 0 0 0 5.36E+07 3.43E+07 - - - 1.3791 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.16158.16158.2 0.0264 16-Oct K.VVDVLDSIK[136.11].T sp|P00918|CAH2_HUMAN 1 994.579 0.84 30949 16158 2 994.580434 498.2968 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.21 3299 - 384993 - - - 1.4298 - 1.932 0.21 - 266.9 1 2 0 0.0014 9 0 0 0 2.71E+07 3.22E+07 - - - 2.4969 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.16162.16162.2 4.72E-05 16-Oct R.FDDPLLGPR[166.11].R "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 8 1038.5374 0.92 30951 16162 2 1038.537387 520.276 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.21 3299.5 - 400485 - - - 0.0212 - 1.735 0.498 - 294.1 1 2 0 0 9 0 0 0 7.43E+07 8.10E+07 - - - 4.3133 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.16164.16164.2 0.0252 12-Jul R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 42.06 30952 16164 2 806.394194 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 3299.7 - 255666 - - - 2.3897 - 1.516 0.265 - 159.6 1 2 0 0.0019 7 0 0 0 5.16E+07 1.23E+06 - - - 2.316 1 230117_WJC_METTL3_WT_vs_EV_F04.16170.16170.2 0.000187 18-Nov K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 348.74 30956 16170 2 1146.631142 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3300.4 - 2.83E+06 - - - 2.3259 - 2.212 0.507 - 362.8 1 2 0 0.0027 10 0 0 0 4.90E+09 1.40E+07 - - - 5.0009 0.9806 230117_WJC_METTL3_WT_vs_EV_F04.16172.16172.2 0.00183 20-Sep K.C[160.03]ILVASPGFVR.E sp|Q9BRX2|PELO_HUMAN 1 1217.6591 3.56 30958 16172 2 1217.665571 609.8368 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 8.25 3300.6 - 427657 - - - 5.3439 - 1.648 0.167 - 271.7 1 2 0 0.0065 11 0 0 0 1.76E+07 4.95E+06 - - - 1.6239 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.16175.16175.3 8.44E-06 15/52 K.NVALLSQLYHSPAR[166.11].R sp|Q15717|ELAV1_HUMAN 1 1577.8553 1.2 30959 16175 3 1577.858592 526.9591 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.75 3301 - 371661 - - - 2.0572 - 2.86 0.392 - 239.2 1 2 0 0.0032 14 0 0 0 6.23E+06 5.18E+06 - - - 5.7021 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.16177.16177.2 0.00874 16-Oct K.VVDVLDSIK.T sp|P00918|CAH2_HUMAN 1 986.5648 0.81 30961 16177 2 986.56605 494.2897 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.21 3301.2 - 708066 - - - 1.2549 - 1.601 0.352 - 260.9 1 2 0 0.0012 9 0 0 0 2.74E+07 3.36E+07 - - - 3.002 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.16182.16182.2 0.0176 18-Oct K.LLADELISPK[136.11].D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1105.6474 1.06 30964 16182 2 1105.649041 553.831 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3301.8 - 1.50E+06 - - - 1.4607 - 2.172 0.36 - 204 1 2 0 0.0016 10 0 0 0 7.03E+07 6.66E+07 - - - 3.8645 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.16183.16183.2 1.28 14-Jun M.VLLTMIAR.V sp|O75396|SC22B_HUMAN 1 915.5576 1.2 30965 16183 2 915.558565 458.7861 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 9.72 3301.9 - 1.43E+06 - - - 1.0988 - 1.365 0.28 - 112.4 1 2 0 0.001 8 0 0 0 7.75E+07 6.46E+07 - - - 2.0472 1 230117_WJC_METTL3_WT_vs_EV_F04.16184.16184.3 2.54E-06 17/52 K.NVALLSQLYHSPAR.R sp|Q15717|ELAV1_HUMAN 1 1567.8471 1.2 30966 16184 3 1567.847975 523.623 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.75 3302 - 678253 - - - 0.5734 - 3.225 0.51 - 324.6 1 2 0 0.0009 14 0 0 0 6.23E+06 5.18E+06 - - - 7.3375 0.9856 230117_WJC_METTL3_WT_vs_EV_F04.16186.16186.2 0.0192 16-Aug R.WLNYGGVIK[136.11].N "sp|P49642|PRI1_HUMAN,tr|F8VSB2|F8VSB2_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN" 3 1056.5848 0.29 30968 16186 2 1056.590769 529.2997 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 8.59 3302.2 - 323686 - - - 5.6815 - 1.519 0.252 - 110.9 1 2 0 0.006 9 0 0 0 3.19E+06 1.09E+07 - - - 2.1098 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.16189.16189.2 0.00466 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.16 30970 16189 2 1235.761674 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3302.6 - 4.11E+06 - - - 1.2268 - 2 0.377 - 302.3 1 2 0 0.0015 11 0 0 0 1.15E+08 9.94E+07 - - - 3.7002 1 230117_WJC_METTL3_WT_vs_EV_F04.16191.16191.2 3.97E-06 20-Nov K.NSLESYAFNMK.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1302.5914 77 30971 16191 2 1302.592351 652.303 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6 3302.8 - 633759 - - - 0.7009 - 2.601 0.587 - 656.1 1 2 0 0.0009 11 0 0 0 1.38E+07 1.79E+05 - - - 5.9622 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.16192.16192.2 0.000219 16-Sep K.AFIGFEGVK.G sp|P15924|DESP_HUMAN 1 966.5175 2.45 30972 16192 2 966.515679 484.266 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.05 3302.9 - 502779 - - - -1.851 - 1.699 0.418 - 221.7 1 2 0 -0.0018 9 0 0 0 5.77E+07 2.35E+07 - - - 3.6612 0.996 230117_WJC_METTL3_WT_vs_EV_F04.16193.16193.2 0.0931 16-Jul R.IVLNGIDLK.A sp|O15294|OGT1_HUMAN 1 983.6015 1.98 30973 16193 2 983.60426 492.808 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 5.84 3303 - 1.23E+06 - - - 2.7735 - 1.557 0.164 - 85.5 1 2 0 0.0027 9 0 0 0 2.88E+07 1.46E+07 - - - 1.5324 0.9366 230117_WJC_METTL3_WT_vs_EV_F04.16197.16197.2 0.0683 14-Sep F.AFLWAGGR.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A1W2PNG3|A0A1W2PNG3_HUMAN" 12 876.4606 1.24 30975 16197 2 876.461394 439.2376 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.79 3303.5 - 679080 - - - 0.8808 - 1.641 0.281 - 260.9 1 1 0 0.0008 8 0 0 0 1.66E+09 1.34E+09 - - - 2.61 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.16198.16198.2 2.11 12-Jul K.ILPDILK.K "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 810.5215 2.07 30976 16198 2 810.523183 406.268 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 3303.6 - 2.47E+06 - - - 2.0875 - 1.351 0.182 - 134.9 1 2 0 0.0017 7 0 0 0 1.02E+08 4.95E+07 - - - 1.338 0.9837 230117_WJC_METTL3_WT_vs_EV_F04.16199.16199.2 0.447 12-Jul K.FAPFEIK[136.11].E "sp|Q13111|CAF1A_HUMAN,tr|K7EPA1|K7EPA1_HUMAN" 2 858.4731 0.77 30977 16199 2 858.4755 430.2438 Chromatin assembly factor 1 subunit A OS=Homo sapiens OX=9606 GN=CHAF1A PE=1 SV=3 6 3303.7 - 898316 - - - 2.8073 - 1.264 0.093 - 137.7 1 2 0 0.0024 7 0 0 0 2.74E+07 3.56E+07 - - - 0.4695 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.16203.16203.2 0.00311 20-Nov K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.16 30980 16203 2 1245.770881 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3304.2 - 2.31E+06 - - - 1.9691 - 1.788 0.398 - 296.5 1 2 0 0.0025 11 0 0 0 1.18E+08 1.02E+08 - - - 3.5519 0.9963 230117_WJC_METTL3_WT_vs_EV_F04.16208.16208.2 0.618 12-Jul K.ILPDILK[136.11].K "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 818.5357 2.38 30984 16208 2 818.536267 410.2751 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 3304.6 - 793587 - - - 0.7037 - 1.378 0.164 - 96 1 2 0 0.0006 7 0 0 0 1.02E+08 4.28E+07 - - - 1.2681 0.9923 230117_WJC_METTL3_WT_vs_EV_F04.16210.16210.2 0.047 16-Jul R.IVLNGIDLK[136.11].A sp|O15294|OGT1_HUMAN 1 991.6157 1.96 30986 16210 2 991.614139 496.8151 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 5.84 3304.7 - 675477 - - - -1.6065 - 1.418 0.229 - 103.3 1 2 0 -0.0016 9 0 0 0 2.85E+07 1.46E+07 - - - 1.7423 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.16215.16215.2 0.00187 12-Aug K.MFEFYER.V "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 13 1020.4375 2.07 30989 16215 2 1020.439234 511.226 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3305.3 - 941866 - - - 1.6963 - 1.524 0.214 - 262.4 1 2 0 0.0017 7 0 0 0 2.17E+07 1.05E+07 - - - 1.9561 0.9462 230117_WJC_METTL3_WT_vs_EV_F04.16216.16216.2 0.58 14-Jul K.LLINDFGR[166.11].E "sp|Q14493|SLBP_HUMAN,tr|H7C4H8|H7C4H8_HUMAN,tr|H0YAE8|H0YAE8_HUMAN,tr|F8W8D3|F8W8D3_HUMAN,tr|E7EUV9|E7EUV9_HUMAN" 5 956.5319 3.06 30990 16216 2 956.537853 479.2732 Histone RNA hairpin-binding protein OS=Homo sapiens OX=9606 GN=SLBP PE=1 SV=1 5.84 3305.4 - 750649 - - - 6.2382 - 1.377 0.169 - 111.3 1 2 0 0.006 8 0 0 0 1.29E+08 4.23E+07 - - - 1.2522 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.16220.16220.2 0.0033 18-Oct R.LTPLQLEIQR[166.11].V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1219.7164 1.12 30993 16220 2 1219.718616 610.8655 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 3305.8 - 986563 - - - 1.8234 - 1.778 0.41 - 357.4 1 2 0 0.0022 10 0 0 0 3.82E+07 3.42E+07 - - - 3.6749 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.16223.16223.2 0.0332 20-Aug K.LLDSITVPVAR[166.11].A sp|O00203|AP3B1_HUMAN 1 1192.7055 1.66 30996 16223 2 1192.710217 597.36 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3306.2 - 243818 - - - 3.9607 - 1.887 0.326 - 150.1 1 2 0 0.0047 11 0 0 0 2.35E+07 1.42E+07 - - - 3.1651 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.16227.16227.2 0.0268 18-Oct K.LLADELISPK.D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1097.6332 1.05 30998 16227 2 1097.635601 549.8239 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3306.7 - 1.87E+06 - - - 2.1637 - 2.058 0.33 - 270.2 1 2 0 0.0024 10 0 0 0 7.04E+07 6.70E+07 - - - 3.4922 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.16229.16229.2 0.00437 18-Oct R.LTPLQLEIQR.V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1209.7081 1.12 31000 16229 2 1209.710168 605.8613 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 3306.9 - 1.64E+06 - - - 1.6913 - 1.845 0.314 - 429.3 1 2 0 0.002 10 0 0 0 3.82E+07 3.42E+07 - - - 3.0692 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.16232.16232.2 0.285 18-Aug K.AMTILLEEAK[136.11].A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1125.6195 1.94 31002 16232 2 1125.621367 563.817 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3307.2 - 275218 - - - 1.6613 - 1.702 0.213 - 150.6 2 2 0 0.0019 10 0 0 0 4.35E+07 2.24E+07 - - - 1.9636 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.16234.16234.2 0.00767 14-Aug R.LLNTFLER.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 8 1004.5655 1.46 31003 16234 2 1004.566492 503.29 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3307.4 - 1.65E+06 - - - 1.0064 - 1.841 0.367 - 186.3 1 2 0 0.001 8 0 0 0 1.68E+08 1.15E+08 - - - 3.592 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.16235.16235.2 0.0203 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 350.66 31004 16235 2 1154.643746 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3307.6 - 477292 - - - 0.9276 - 1.488 0.342 - 263.2 1 2 0 0.0011 10 0 0 0 4.90E+09 1.40E+07 - - - 2.676 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.16236.16236.2 0.00465 14-Aug K.FYSFALDK.T sp|Q96T58|MINT_HUMAN 1 989.4858 0.89 31005 16236 2 989.487798 495.7502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.83 3307.7 - 752516 - - - 1.9849 - 1.542 0.323 - 144.7 1 2 0 0.002 8 0 0 0 3.26E+07 3.65E+07 - - - 2.7322 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.16241.16241.2 0.113 14-Aug R.LMGLEALK.S "sp|P48643|TCPE_HUMAN,tr|D6RIZ7|D6RIZ7_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0Y914|H0Y914_HUMAN" 4 873.4994 5.77 31008 16241 2 873.501251 437.757 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 3308.3 - 5.86E+06 - - - 2.1477 - 1.583 0.223 - 183.6 1 2 0 0.0019 8 0 0 0 2.21E+09 3.82E+08 - - - 2.0728 1 230117_WJC_METTL3_WT_vs_EV_F04.16252.16252.2 0.00452 20-Nov K.LLDSITVPVAR.A sp|O00203|AP3B1_HUMAN 1 1182.6972 1.66 31014 16252 2 1182.698093 592.3559 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3309.6 - 283781 - - - 0.7356 - 2.269 0.465 - 350.1 1 2 0 0.0009 11 0 0 0 2.36E+07 1.42E+07 - - - 4.6917 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.16259.16259.2 1.3 12-Aug K.LMVIFSK.V "sp|Q9BRK5|CAB45_HUMAN,tr|A0A5F9UJX7|A0A5F9UJX7_HUMAN,tr|A0A5F9UP49|A0A5F9UP49_HUMAN,tr|G3V1E2|G3V1E2_HUMAN,tr|H0Y3T6|H0Y3T6_HUMAN" 5 836.483 0.41 31019 16259 2 836.482812 419.2488 45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1 8.75 3310.3 - 513799 - - - -0.2212 - 1.78 0.201 - 190.2 1 2 0 -0.0002 7 0 0 0 2.58E+07 6.28E+07 - - - 2.3526 0.998 230117_WJC_METTL3_WT_vs_EV_F04.16263.16263.2 0.0063 18-Oct K.LGLTEDQFIR.T "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1190.6295 2.89 31021 16263 2 1190.629249 596.322 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.37 3310.8 - 622104 - - - -0.2427 - 1.538 0.266 - 206.1 1 2 0 -0.0003 10 0 0 0 1.39E+07 4.82E+06 - - - 2.2072 1 230117_WJC_METTL3_WT_vs_EV_F04.16268.16268.2 0.000412 15/22 K.LGALTAEEIALK.M sp|Q13601|KRR1_HUMAN 1 1227.7075 1.28 31023 16268 2 1227.708656 614.861 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3311.5 - 875037 - - - 0.9791 - 2.464 0.493 - 691.3 1 2 0 0.0012 12 0 0 0 1.29E+08 1.01E+08 - - - 5.0547 0.8958 230117_WJC_METTL3_WT_vs_EV_F04.16269.16269.2 0.000504 22-Oct R.GLLQDDAHPTLV.T "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1277.6616 - 31024 16269 2 1277.660115 639.8381 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3311.7 - 487521 - - - -1.1357 - 1.741 0.371 - 205.3 1 1 0 -0.0015 12 0 0 0 - - - - - 3.2396 1 230117_WJC_METTL3_WT_vs_EV_F04.16277.16277.2 5.71E-05 22-Dec R.VFASELNAGIIK[136.11].T "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1268.722 1.72 31030 16277 2 1268.727919 635.3683 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.97 3312.7 - 522048 - - - 4.6748 - 2.275 0.506 - 417.8 1 2 0 0.0059 12 0 0 0 1.66E+07 9.69E+06 - - - 4.9392 0.9738 230117_WJC_METTL3_WT_vs_EV_F04.16281.16281.2 0.00877 18-Aug F.LLVGTQIDLR.D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1126.671 1.44 31032 16281 2 1126.672276 564.3428 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.84 3313.2 - 335787 - - - 1.1246 - 2.031 0.387 - 214.3 1 1 0 0.0013 10 0 0 0 1.42E+07 9.83E+06 - - - 3.8767 1 230117_WJC_METTL3_WT_vs_EV_F04.16286.16286.2 0.000143 13/22 K.LGALTAEEIALK[136.11].M sp|Q13601|KRR1_HUMAN 1 1235.7217 1.28 31035 16286 2 1235.714853 618.8681 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3313.8 - 1.38E+06 - - - -5.5037 - 2.512 0.444 - 550.9 1 2 0 -0.0068 12 0 0 0 1.29E+08 1.01E+08 - - - 4.7418 0.998 230117_WJC_METTL3_WT_vs_EV_F04.16289.16289.2 0.105 14-Jun K.VLTFDLTK.Y "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 935.5328 2.73 31036 16289 2 935.533523 468.7737 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.81 3314.2 - 4.40E+06 - - - 0.7899 - 1.242 0.282 - 118 1 2 0 0.0007 8 0 0 0 9.51E+07 3.49E+07 - - - 1.7772 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.16291.16291.2 0.0315 18-Sep K.IPVSGPFLVK[136.11].T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1063.6521 1.27 31038 16291 2 1063.652902 532.8333 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3314.5 - 968995 - - - 0.7371 - 1.523 0.273 - 198.4 1 2 0 0.0008 10 0 0 0 1.62E+08 1.27E+08 - - - 2.2314 0.9806 230117_WJC_METTL3_WT_vs_EV_F04.16294.16294.2 0.63 16-Jul R.LLSVLATVK[136.11].Q sp|O75063|XYLK_HUMAN 1 950.6256 0.62 31039 16294 2 950.624875 476.3201 Glycosaminoglycan xylosylkinase OS=Homo sapiens OX=9606 GN=FAM20B PE=1 SV=1 8.75 3314.9 - 898218 - - - -0.729 - 1.134 0.159 - 87.6 1 2 0 -0.0007 9 0 0 0 2.19E+07 3.55E+07 - - - 0.579 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.16297.16297.2 0.127 16-Jun K.VILTSPLIR[166.11].D sp|Q96SI9|STRBP_HUMAN 1 1020.6571 2.02 31042 16297 2 1020.659255 511.3358 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 9.72 3315.2 - 411191 - - - 2.1241 - 1.243 0.27 - 73 1 2 0 0.0022 9 0 0 0 5.20E+07 2.58E+07 - - - 1.6639 1 230117_WJC_METTL3_WT_vs_EV_F04.16306.16306.2 1.18E-05 13/22 K.VLVALASEELAK[136.11].G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1249.7373 1.68 31047 16306 2 1249.74121 625.8759 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.53 3316.4 - 630231 - - - 3.1255 - 2.668 0.503 - 461.7 1 2 0 0.0039 12 0 0 0 5.54E+07 3.30E+07 - - - 5.337 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.16309.16309.2 0.0371 16-Oct R.IGLINDMVR[166.11].F sp|Q14152|EIF3A_HUMAN 1 1039.5724 1.1 31050 16309 2 1039.572628 520.7935 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.84 3316.8 - 645745 - - - 0.2472 - 1.72 0.242 - 252.4 1 2 0 0.0003 9 0 0 0 8.91E+07 8.08E+07 - - - 2.3973 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.16314.16314.2 0.00211 16-Aug R.SAVYPLLYR.D "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H7C184|H7C184_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1080.5968 1.65 31053 16314 2 1080.594224 541.3057 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 8.31 3317.4 - 205374 - - - -2.3663 - 1.977 0.361 - 240.5 1 2 0 -0.0026 9 0 0 0 1.68E+07 1.02E+07 - - - 3.6784 0.9905 230117_WJC_METTL3_WT_vs_EV_F04.16316.16316.2 0.682 12-Jun K.LMFEELR.N sp|Q9Y3I0|RTCB_HUMAN 1 936.4739 1.07 31055 16316 2 936.476468 469.2442 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.53 3317.5 - 1.74E+06 - - - 2.7539 - 1.197 0.166 - 121.7 1 2 0 0.0026 7 0 0 0 1.13E+08 1.06E+08 - - - 0.836 1 230117_WJC_METTL3_WT_vs_EV_F04.16321.16321.2 2.41E-06 22-Nov K.VLVALASEELAK.G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1241.7231 1.68 31058 16321 2 1241.724418 621.8688 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.53 3318.1 - 598191 - - - 1.0582 - 2.304 0.514 - 360.4 1 2 0 0.0013 12 0 0 0 5.55E+07 3.30E+07 - - - 5.0331 1 230117_WJC_METTL3_WT_vs_EV_F04.16322.16322.2 7.26E-06 20-Oct R.LLTGVEYVVGR.K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1204.6816 1.48 31059 16322 2 1204.684121 603.3481 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3318.2 - 153967 - - - 2.1151 - 2.095 0.534 - 316.8 1 2 0 0.0025 11 0 0 0 3.17E+07 2.14E+07 - - - 4.985 0.9924 230117_WJC_METTL3_WT_vs_EV_F04.16324.16324.2 0.0563 12-Jul K.LMFEELR[166.11].N sp|Q9Y3I0|RTCB_HUMAN 1 946.4822 1.07 31061 16324 2 946.479956 474.2484 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.53 3318.3 - 1.88E+06 - - - -2.3276 - 1.115 0.38 - 114.1 1 2 0 -0.0022 7 0 0 0 1.13E+08 1.06E+08 - - - 2.1919 0.9965 230117_WJC_METTL3_WT_vs_EV_F04.16329.16329.2 0.752 12-Jul K.LIIFDAR.Q "sp|Q13613|MTMR1_HUMAN,tr|Q8NEC6|Q8NEC6_HUMAN,tr|F8WA39|F8WA39_HUMAN,tr|H0YDX3|H0YDX3_HUMAN" 4 846.4963 3.41 31065 16329 2 846.496509 424.2554 Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4 5.84 3318.8 - 4.16E+06 - - - 0.2008 - 1.461 0.169 - 175.2 1 2 0 0.0002 7 0 0 0 9.75E+07 2.86E+07 - - - 1.4904 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.16332.16332.2 0.0451 16-Oct K.ALLSTVLSR.S "sp|Q5H9F3|BCORL_HUMAN,tr|H7C4B2|H7C4B2_HUMAN" 2 958.5811 2.56 31067 16332 2 958.580914 480.2978 BCL-6 corepressor-like protein 1 OS=Homo sapiens OX=9606 GN=BCORL1 PE=1 SV=1 9.79 3319.1 - 382055 - - - -0.2264 - 2.139 0.225 - 248.3 1 2 0 -0.0002 9 0 0 0 1.03E+07 4.03E+06 - - - 2.9025 1 230117_WJC_METTL3_WT_vs_EV_F04.16333.16333.2 7.19E-05 20-Nov R.LLTGVEYVVGR[166.11].K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1214.6898 1.51 31068 16333 2 1214.691186 608.3522 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3319.3 - 483116 - - - 1.1056 - 2.271 0.472 - 383.5 1 2 0 0.0013 11 0 0 0 3.23E+07 2.15E+07 - - - 4.7457 0.8619 230117_WJC_METTL3_WT_vs_EV_F04.16339.16339.2 2.63 12-Jun R.VWQILER[166.11].T sp|Q93100|KPBB_HUMAN 1 952.537 1.14 31072 16339 2 952.534448 477.2758 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 5.97 3319.9 - 760404 - - - -2.6487 - 1.226 0.06 - 107.4 2 2 0 -0.0025 7 0 0 0 1.73E+07 1.52E+07 - - - -0.0055 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.16346.16346.2 0.0039 20-Sep K.VLEVPPVVYSR.Q "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1256.7129 0.76 31077 16346 2 1256.717118 629.3637 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 5.97 3320.8 - 462292 - - - 3.3779 - 1.828 0.432 - 201.6 1 2 0 0.0042 11 0 0 0 8.85E+06 1.16E+07 - - - 3.8623 0.9957 230117_WJC_METTL3_WT_vs_EV_F04.16354.16354.2 1.97 12-Aug M.LPLSLLK.T "sp|Q9Y4Z0|LSM4_HUMAN,sp|Q969I6|S38A4_HUMAN,tr|F8VQY9|F8VQY9_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 5 782.5266 19.08 31082 16354 2 782.526847 392.2706 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 8.75 3321.8 - 898705 - - - 0.3463 - 1.678 0.078 - 193.5 1 2 0 0.0003 7 0 0 0 2.34E+07 1.23E+06 - - - 1.2571 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.16361.16361.2 0.00328 14-Aug K.VTNLLMLK.G "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|B4DI28|B4DI28_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|X6R242|X6R242_HUMAN,tr|A0A6Q8PH43|A0A6Q8PH43_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 18 930.5572 1.15 31087 16361 2 930.558164 466.2859 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.72 3322.6 - 1.05E+06 - - - 1.0101 - 1.752 0.328 - 201.1 1 2 0 0.0009 8 0 0 0 6.19E+08 5.38E+08 - - - 3.1545 0.9519 230117_WJC_METTL3_WT_vs_EV_F04.16363.16363.2 0.0655 12-May R.EAYYWLR[166.11].H sp|P46977|STT3A_HUMAN 1 1009.4897 1.27 31088 16363 2 1009.489979 505.7521 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6.1 3322.8 - 847133 - - - 0.2893 - 1.14 0.017 - 104.1 1 2 0 0.0003 7 0 0 0 4.38E+07 3.45E+07 - - - -0.4184 0.9578 230117_WJC_METTL3_WT_vs_EV_F04.16364.16364.2 0.565 12-Jul R.EAYYWLR.H sp|P46977|STT3A_HUMAN 1 999.4814 1.28 31089 16364 2 999.477118 500.748 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6.1 3322.9 - 2.66E+06 - - - -4.3012 - 1.388 0.221 - 225.8 1 2 0 -0.0043 7 0 0 0 4.43E+07 3.46E+07 - - - 1.7108 0.9914 230117_WJC_METTL3_WT_vs_EV_F04.16366.16366.2 0.296 20-Jul K.VLEVPPVVYSR[166.11].Q "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1266.7211 0.86 31091 16366 2 1266.726611 634.3678 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 5.97 3323.1 - 249011 - - - 4.3167 - 1.554 0.202 - 177.7 1 2 0 0.0055 11 0 0 0 1.02E+07 1.18E+07 - - - 1.7238 0.9946 230117_WJC_METTL3_WT_vs_EV_F04.16372.16372.2 0.485 12-Jul K.LWVLETK[136.11].E "sp|Q15061|WDR43_HUMAN,tr|C9JEE7|C9JEE7_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 3 895.5259 4.67 31094 16372 2 895.525299 448.7702 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3323.9 - 1.35E+06 - - - -0.6197 - 1.442 0.178 - 165.9 1 2 0 -0.0006 7 0 0 0 2.15E+08 4.60E+07 - - - 1.5153 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.16375.16375.2 0.0149 18-Aug K.LVALAVIDEK[136.11].N sp|Q96JJ7|TMX3_HUMAN 1 1077.6525 2.05 31096 16375 2 1077.651445 539.8335 Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2 4.37 3324.2 - 502083 - - - -0.9892 - 2.057 0.373 - 111 1 2 0 -0.0011 10 0 0 0 1.73E+07 8.42E+06 - - - 3.8089 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.16376.16376.2 0.0859 20-Nov R.IDALLAVDPPR.A sp|P50219|MNX1_HUMAN 1 1178.6659 1.75 31097 16376 2 1178.668039 590.3402 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3324.3 - 957673 - - - 1.7953 - 2.397 0.347 - 372 1 2 0 0.0021 11 0 0 0 3.15E+07 1.81E+07 - - - 3.9682 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.16381.16381.2 0.0101 12-Jun K.LWYTLDR[166.11].A sp|P00387|NB5R3_HUMAN 1 975.5053 1.8 31100 16381 2 975.506434 488.7599 NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3 5.84 3325 - 1.03E+06 - - - 1.1245 - 1.513 0.168 - 126 1 2 0 0.0011 7 0 0 0 4.62E+07 2.57E+07 - - - 1.5936 1 230117_WJC_METTL3_WT_vs_EV_F04.16391.16391.2 1.67E-05 20-Dec R.VGASEAALFLK.K "sp|Q9UBC2|EP15R_HUMAN,tr|M0QX30|M0QX30_HUMAN,tr|K7EJR2|K7EJR2_HUMAN,tr|M0R1V5|M0R1V5_HUMAN,tr|M0R330|M0R330_HUMAN,tr|M0R165|M0R165_HUMAN" 6 1104.6179 0.48 31108 16391 2 1104.620276 553.3162 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 5.97 3326.2 - 754865 - - - 2.1419 - 2.303 0.506 - 436.7 1 2 0 0.0024 11 0 0 0 1.02E+07 2.11E+07 - - - 5.0343 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.16396.16396.2 0.233 12-Sep R.LSAILFK.L "sp|Q9NSV4|DIAP3_HUMAN,sp|Q12830|BPTF_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|J3KSK9|J3KSK9_HUMAN,tr|J3QQQ8|J3QQQ8_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN" 7 790.4953 1.42 31111 16396 2 790.497369 396.2549 Protein diaphanous homolog 3 OS=Homo sapiens OX=9606 GN=DIAPH3 PE=1 SV=4 8.75 3326.9 - 790691 - - - 2.6477 - 1.552 0.121 - 240.8 1 2 0 0.0021 7 0 0 0 1.92E+07 1.35E+07 - - - 1.3268 0.9865 230117_WJC_METTL3_WT_vs_EV_F04.16397.16397.2 0.922 20-Sep R.IDALLAVDPPR[166.11].A sp|P50219|MNX1_HUMAN 1 1188.6742 1.79 31112 16397 2 1188.680577 595.3444 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3327 - 173646 - - - 5.3707 - 1.816 0.179 - 267.5 1 2 0 0.0064 11 0 0 0 3.44E+07 1.92E+07 - - - 1.9751 0.9954 230117_WJC_METTL3_WT_vs_EV_F04.16404.16404.2 0.403 16-Jun K.YIIEELNVR[166.11].K "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1157.632 26.17 31117 16404 2 1157.632619 579.8233 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.53 3327.9 - 187428 - - - 0.5399 - 1.326 0.175 - 95.4 1 2 0 0.0006 9 0 0 0 1.13E+08 4.32E+06 - - - 1.1497 0.9911 230117_WJC_METTL3_WT_vs_EV_F04.16405.16405.2 0.898 12-Jul R.LLLDSLR.K sp|Q10469|MGAT2_HUMAN 1 828.5069 1.05 31118 16405 2 828.508607 415.2607 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 5.84 3328 - 2.55E+06 - - - 2.0567 - 1.433 0.062 - 160.3 1 2 0 0.0017 7 0 0 0 3.27E+07 3.12E+07 - - - 0.6383 0.9943 230117_WJC_METTL3_WT_vs_EV_F04.16413.16413.2 0.724 12-Jul R.LLLDSLR[166.11].K sp|Q10469|MGAT2_HUMAN 1 838.5152 1.06 31124 16413 2 838.516418 420.2649 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 5.84 3329 - 1.60E+06 - - - 1.4848 - 1.474 0.083 - 161.9 1 2 0 0.0012 7 0 0 0 3.30E+07 3.12E+07 - - - 0.883 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.16414.16414.2 1.62 14-Aug R.ALDIPLVK.N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 867.543 1.39 31125 16414 2 867.543911 434.7788 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3329.2 - 1.62E+06 - - - 1.1031 - 1.487 0.192 - 237.1 1 2 0 0.001 8 0 0 0 1.29E+08 9.31E+07 - - - 1.6554 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.16415.16415.2 0.077 14-Jul R.LIGWGQIR[166.11].R "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 951.553 0.86 31126 16415 2 951.555182 476.7838 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 9.75 3329.2 - 6.26E+06 - - - 2.3393 - 1.421 0.217 - 132.2 1 2 0 0.0022 8 0 0 0 7.21E+07 8.37E+07 - - - 1.7028 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.16416.16416.2 0.0467 12-Aug K.FVSFLGR[166.11].T "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 834.4627 1.16 31127 16416 2 834.464702 418.2386 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 9.75 3329.3 - 2.40E+06 - - - 2.3464 - 1.507 0.332 - 215.2 1 2 0 0.002 7 0 0 0 1.83E+08 1.58E+08 - - - 2.792 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.16419.16419.2 0.00134 16-Oct R.SPVYLTVLK[136.11].H "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1026.6205 1.59 31130 16419 2 1026.624375 514.3175 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 8.31 3329.6 - 509398 - - - 3.7911 - 1.958 0.347 - 317.4 1 2 0 0.0039 9 0 0 0 1.64E+07 1.03E+07 - - - 3.5466 0.9826 230117_WJC_METTL3_WT_vs_EV_F04.16420.16420.2 0.000488 16-Aug K.GLIDYETFK.E sp|P15924|DESP_HUMAN 1 1084.5441 1.87 31131 16420 2 1084.552389 543.2793 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3329.8 - 171369 - - - 7.664 - 1.65 0.379 - 148.8 1 2 0 0.0083 9 0 0 0 4.98E+06 2.66E+06 - - - 3.2865 1 230117_WJC_METTL3_WT_vs_EV_F04.16421.16421.2 7.20E-07 26-Oct F.LLIGGGTAAFAAAR.S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1287.7299 4.79 31132 16421 2 1287.729528 644.8722 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3329.9 - 119567 - - - -0.3044 - 2.161 0.503 - 274.3 1 1 0 -0.0004 14 0 0 0 9.73E+06 2.03E+06 - - - 4.6897 1 230117_WJC_METTL3_WT_vs_EV_F04.16424.16424.2 4.73E-05 16-Sep K.GPLMMYISK.M sp|P13639|EF2_HUMAN 1 1038.5242 0.06 31134 16424 2 1038.528102 520.2694 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 3330.2 - 1.42E+06 - - - 3.7476 - 2.007 0.479 - 377.2 1 2 0 0.0039 9 0 0 0 4.43E+07 6.99E+08 - - - 4.5931 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.16426.16426.2 0.468 14-Jul R.ALDIPLVK[136.11].N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 875.5572 1.39 31136 16426 2 875.558364 438.7859 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3330.3 - 2.87E+06 - - - 1.382 - 1.53 0.244 - 163.5 1 2 0 0.0012 8 0 0 0 1.29E+08 9.31E+07 - - - 2.1254 1 230117_WJC_METTL3_WT_vs_EV_F04.16429.16429.2 4.36E-09 14/22 K.LNDLEEALQQAK.E sp|P35908|K22E_HUMAN 1 1370.7042 999 31139 16429 2 1370.707021 686.3594 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3330.7 - 365043 - - - 2.088 - 2.66 0.549 - 819 1 2 0 0.0029 12 0 0 0 2.72E+06 0.00E+00 - - - 5.6692 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.16431.16431.2 0.00186 18-Nov K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 38.67 31140 16431 2 1146.630819 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3331 - 1.27E+06 - - - 2.0443 - 2.075 0.463 - 357.1 1 2 0 0.0023 10 0 0 0 2.56E+08 6.62E+06 - - - 4.4975 0.999 230117_WJC_METTL3_WT_vs_EV_F04.16433.16433.2 0.00645 16-Sep R.SLFVVVGDR[166.11].G "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 1000.5581 0.44 31142 16433 2 1000.560973 501.2863 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.55 3331.1 - 1.71E+06 - - - 2.8704 - 1.885 0.283 - 363.4 1 2 0 0.0029 9 0 0 0 1.10E+07 2.51E+07 - - - 2.9643 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.16436.16436.2 0.00104 22-Jul R.MPGSVIPPPLVR[166.11].G sp|Q86YP4|P66A_HUMAN 1 1271.7299 3.03 31145 16436 2 1271.733942 636.8722 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.5 3331.5 - 112252 - - - 3.1516 - 1.673 0.37 - 122 1 2 0 0.004 12 0 0 0 8.85E+06 2.92E+06 - - - 3.1266 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.16438.16438.2 0.000339 14-Aug K.VIFLENYR.V "sp|P06737|PYGL_HUMAN,sp|P11217|PYGM_HUMAN,sp|P11216|PYGB_HUMAN,tr|E9PK47|E9PK47_HUMAN,tr|H0Y4Z6|H0Y4Z6_HUMAN" 5 1052.5655 5.42 31146 16438 2 1052.568161 527.29 "Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL PE=1 SV=4" 5.97 3331.8 - 4.57E+06 - - - 2.5462 - 1.863 0.452 - 248 1 2 0 0.0027 8 0 0 0 5.37E+07 9.91E+06 - - - 4.2551 1 230117_WJC_METTL3_WT_vs_EV_F04.16439.16439.2 0.0011 16-Oct R.SLFVVVGDR.G "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 990.5498 0.07 31147 16439 2 990.553555 496.2822 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.55 3331.9 - 1.88E+06 - - - 3.7595 - 2.074 0.479 - 483.8 1 2 0 0.0037 9 0 0 0 1.77E+07 2.53E+08 - - - 4.6881 0.999 230117_WJC_METTL3_WT_vs_EV_F04.16447.16447.2 0.167 14-Aug K.VIILSLDR.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 927.5753 2.42 31153 16447 2 927.57801 464.7949 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.81 3332.9 - 1.09E+07 - - - 2.9033 - 1.785 0.302 - 257.5 1 2 0 0.0027 8 0 0 0 1.93E+08 7.99E+07 - - - 3.0182 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.16449.16449.2 0.0107 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.16 31155 16449 2 1235.763559 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3333 - 2.11E+06 - - - 2.7522 - 1.939 0.331 - 258.2 1 2 0 0.0034 11 0 0 0 2.02E+07 1.74E+07 - - - 3.276 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.16450.16450.2 0.000171 16-Sep K.GPLMMYISK[136.11].M sp|P13639|EF2_HUMAN 1 1046.5384 1.77 31156 16450 2 1046.5402 524.2765 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 3333.1 - 1.02E+06 - - - 1.7104 - 1.947 0.465 - 340.8 1 2 0 0.0018 9 0 0 0 2.66E+07 1.50E+07 - - - 4.4025 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.16460.16460.2 0.000863 12-Aug K.YYTLFGR.S sp|P07814|SYEP_HUMAN 1 918.46 1.15 31164 16460 2 918.462677 460.2373 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.59 3334.5 - 3.50E+06 - - - 2.9658 - 1.537 0.418 - 187.4 1 2 0 0.0027 7 0 0 0 6.72E+07 5.84E+07 - - - 3.4894 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.16461.16461.2 6.31E-05 18-Sep K.AAPEMVSLLK[136.11].R "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN,tr|K7EQ99|K7EQ99_HUMAN" 3 1065.5984 1.16 31165 16461 2 1065.60157 533.8065 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 6.05 3334.5 - 2.01E+06 - - - 3.0058 - 1.742 0.484 - 334.7 1 2 0 0.0032 10 0 0 0 3.70E+07 3.20E+07 - - - 4.1641 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.16463.16463.2 0.0412 20-Aug K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.16 31167 16463 2 1245.770981 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3334.7 - 1.55E+06 - - - 2.0493 - 1.754 0.406 - 176.2 1 2 0 0.0026 11 0 0 0 2.02E+07 1.74E+07 - - - 3.559 0.9833 230117_WJC_METTL3_WT_vs_EV_F04.16466.16466.2 0.422 12-Jun K.LPLLLSR.M "sp|P49902|5NTC_HUMAN,sp|O95866|G6B_HUMAN,tr|A0A140T9L8|A0A140T9L8_HUMAN,tr|A0A6Q8PHB5|A0A6Q8PHB5_HUMAN,tr|A0A140T9V1|A0A140T9V1_HUMAN,tr|A0A6Q8PHP0|A0A6Q8PHP0_HUMAN,tr|B7ZLJ5|B7ZLJ5_HUMAN,tr|A0A0G2JJG8|A0A0G2JJG8_HUMAN,tr|F8WDG3|F8WDG3_HUMAN,tr|Q5JUV4|Q5JUV4_HUMAN" 10 810.5327 0.84 31170 16466 2 810.53428 406.2736 Cytosolic purine 5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5C2 PE=1 SV=1 9.75 3334.9 - 618817 - - - 1.9197 - 1.387 0.042 - 143.9 3 2 0 0.0016 7 0 0 0 1.31E+07 1.56E+07 - - - 0.1742 1 230117_WJC_METTL3_WT_vs_EV_F04.16468.16468.2 0.0153 26-Dec F.LLIGGGTAAFAAAR[166.11].S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1297.7382 4.79 31172 16468 2 1297.741047 649.8764 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3335.2 - 295169 - - - 2.2015 - 2.254 0.487 - 362.4 1 1 0 0.0029 14 0 0 0 9.73E+06 2.03E+06 - - - 4.6765 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.16472.16472.2 0.0771 16-Jul R.LVLQYAPSA.- "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN" 2 960.528 - 31175 16472 2 960.529536 481.2713 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 5.52 3335.7 - 5.89E+06 - - - 1.5648 - 1.314 0.163 - 141.2 1 2 0 0.0015 9 0 0 0 - - - - - 1.0345 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.16475.16475.2 0.0105 14-Aug K.VIILSLDR[166.11].S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 937.5836 2.53 31177 16475 2 937.585068 469.7991 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.81 3336 - 5.37E+06 - - - 1.5796 - 1.738 0.341 - 222.8 1 2 0 0.0015 8 0 0 0 1.92E+08 7.58E+07 - - - 3.2262 0.999 230117_WJC_METTL3_WT_vs_EV_F04.16476.16476.2 0.0114 12-Aug R.SFDLLVK[136.11].N sp|Q9HB71|CYBP_HUMAN 1 828.4837 2.13 31178 16476 2 828.483971 415.2491 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 5.55 3336 - 5.34E+06 - - - 0.3814 - 1.526 0.308 - 201.5 1 2 0 0.0003 7 0 0 0 9.83E+07 4.61E+07 - - - 2.655 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.16479.16479.2 1.05 14-Sep K.LLELLPGK[136.11].V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 889.5728 2.08 31181 16479 2 889.57522 445.7937 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3336.3 - 1.53E+06 - - - 2.7148 - 1.332 0.242 - 204.7 1 2 0 0.0024 8 0 0 0 1.00E+08 4.83E+07 - - - 1.6923 0.9034 230117_WJC_METTL3_WT_vs_EV_F04.16482.16482.2 0.534 12-Jun R.YLFPVPK.D "sp|Q96G21|IMP4_HUMAN,tr|E7ENR5|E7ENR5_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN,tr|B9A008|B9A008_HUMAN" 5 862.4953 1.25 31184 16482 2 862.500269 432.2549 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 8.59 3336.7 - 573084 - - - 5.789 - 1.188 0.132 - 131.5 1 2 0 0.005 7 0 0 0 4.70E+06 3.75E+06 - - - 0.5602 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.16490.16490.2 0.614 14-Aug K.LLELLPGK.V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 881.5586 2.08 31190 16490 2 881.560538 441.7866 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3337.6 - 4.89E+06 - - - 2.1927 - 1.683 0.205 - 199.2 1 2 0 0.0019 8 0 0 0 1.00E+08 4.83E+07 - - - 2.1246 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.16491.16491.2 0.0552 16-Nov K.NAIVVLIPK.Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 965.6274 1.89 31191 16491 2 965.629942 483.821 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3337.7 - 2.78E+06 - - - 2.6812 - 1.721 0.411 - 478.1 1 2 0 0.0026 9 0 0 0 1.85E+08 9.79E+07 - - - 3.6465 0.999 230117_WJC_METTL3_WT_vs_EV_F04.16492.16492.2 0.0577 16-Sep K.NAIVVLIPK[136.11].Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 973.6416 1.89 31192 16492 2 973.64492 487.8281 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3337.8 - 1.55E+06 - - - 3.4582 - 1.72 0.402 - 178.9 1 2 0 0.0034 9 0 0 0 1.85E+08 9.79E+07 - - - 3.5781 1 230117_WJC_METTL3_WT_vs_EV_F04.16493.16493.2 0.000301 20-Dec K.NALESYAFNMK.S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1286.5965 17.6 31193 16493 2 1286.600012 644.3055 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3337.9 - 1.19E+06 - - - 2.7118 - 2.543 0.463 - 540.4 1 2 0 0.0035 11 0 0 0 1.62E+07 9.23E+05 - - - 4.9845 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.16494.16494.2 0.0317 16-Aug R.LIPDFPVAR.S sp|Q96S55|WRIP1_HUMAN 1 1026.5862 4.82 31194 16494 2 1026.589158 514.3004 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 5.84 3338.1 - 985508 - - - 2.8658 - 1.431 0.337 - 207.1 1 2 0 0.0029 9 0 0 0 4.05E+07 8.40E+06 - - - 2.566 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.16495.16495.2 0.000471 20-Sep R.LVMELSGEMVR.K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1262.6363 1.94 31195 16495 2 1262.64104 632.3254 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3338.2 - 631720 - - - 3.7707 - 1.69 0.432 - 218.3 1 2 0 0.0048 11 0 0 0 1.35E+07 6.95E+06 - - - 3.6498 0.9633 230117_WJC_METTL3_WT_vs_EV_F04.16496.16496.2 0.509 16-Aug R.ALAYFEQLK.L "sp|O43592|XPOT_HUMAN,tr|F5GYW6|F5GYW6_HUMAN,tr|F8WDU6|F8WDU6_HUMAN" 3 1081.5808 3.67 31196 16496 2 1081.585312 541.7977 Exportin-T OS=Homo sapiens OX=9606 GN=XPOT PE=1 SV=2 6.05 3338.3 - 572077 - - - 4.1744 - 1.415 0.063 - 149.9 1 2 0 0.0045 9 0 0 0 5.58E+06 1.52E+06 - - - 0.5092 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.16497.16497.2 0.000102 20-Oct R.LVMELSGEMVR[166.11].K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1272.6445 1.94 31197 16497 2 1272.650309 637.3296 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3338.5 - 469002 - - - 4.526 - 1.889 0.412 - 292.4 1 2 0 0.0058 11 0 0 0 1.35E+07 6.95E+06 - - - 3.8029 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.16501.16501.2 0.179 18-Aug R.LLPQVDSVLK.S "sp|Q9C0B9|ZCHC2_HUMAN,tr|K7EKB8|K7EKB8_HUMAN,tr|K7ESN2|K7ESN2_HUMAN" 3 1110.6649 2.71 31201 16501 2 1110.667686 556.3397 Zinc finger CCHC domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZCCHC2 PE=1 SV=6 5.84 3339 - 188638 - - - 2.5435 - 1.401 0.263 - 107 1 2 0 0.0028 10 0 0 0 1.56E+06 5.74E+05 - - - 1.9238 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.16506.16506.2 0.0204 20-Oct K.LISSVDPQFLK.L "sp|Q9BVG4|PBDC1_HUMAN,tr|A6NDF3|A6NDF3_HUMAN" 2 1245.6969 4.87 31204 16506 2 1245.69957 623.8557 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 5.84 3339.6 - 1.77E+06 - - - 2.1522 - 1.594 0.37 - 225.8 1 2 0 0.0027 11 0 0 0 2.89E+07 5.94E+06 - - - 3.0343 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.16507.16507.2 0.00131 16-Sep R.FLIIDEADR.M sp|Q8N8A6|DDX51_HUMAN 1 1090.5659 1.27 31205 16507 2 1090.56918 546.2902 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 4.03 3339.7 - 2.46E+06 - - - 3.0305 - 2.012 0.384 - 307.4 1 2 0 0.0033 9 0 0 0 2.76E+07 2.18E+07 - - - 3.8988 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.16513.16513.2 0.00288 16-Sep R.LTQEVLLLR.E "sp|Q5VU43|MYOME_HUMAN,tr|E9PQG4|E9PQG4_HUMAN,tr|A0A087WX83|A0A087WX83_HUMAN,tr|A0A075B749|A0A075B749_HUMAN" 4 1083.6652 2.29 31211 16513 2 1083.667194 542.8399 Myomegalin OS=Homo sapiens OX=9606 GN=PDE4DIP PE=1 SV=3 6 3340.3 - 716072 - - - 1.8447 - 2.074 0.235 - 275.6 1 2 0 0.002 9 0 0 0 1.53E+07 6.69E+06 - - - 2.8865 0.9962 230117_WJC_METTL3_WT_vs_EV_F04.16515.16515.2 0.132 14-Jul K.SIILEGFK.S sp|O95347|SMC2_HUMAN 1 905.5222 0.13 31213 16515 2 905.523761 453.7684 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 5.72 3340.5 - 219492 - - - 1.7029 - 1.246 0.205 - 110.6 1 2 0 0.0015 8 0 0 0 2.95E+06 2.21E+07 - - - 1.218 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.16520.16520.2 0.0249 16-Jul K.VYLGDIPLK[136.11].T "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1024.6048 1.46 31216 16520 2 1024.605498 513.3097 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.81 3341.2 - 2.00E+06 - - - 0.649 - 1.371 0.277 - 162.1 1 2 0 0.0007 9 0 0 0 3.99E+07 2.74E+07 - - - 1.9996 0.9892 230117_WJC_METTL3_WT_vs_EV_F04.16521.16521.2 0.00558 16-Oct R.LLQSLLDTR.C sp|Q13045|FLII_HUMAN 1 1057.6132 1.59 31217 16521 2 1057.620625 529.8139 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3341.2 - 2.69E+06 - - - 7.0593 - 1.982 0.343 - 340.5 1 2 0 0.0075 9 0 0 0 1.98E+07 1.25E+07 - - - 3.5512 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.16522.16522.2 0.000682 16-Aug R.LLQSLLDTR[166.11].C sp|Q13045|FLII_HUMAN 1 1067.6214 1.59 31218 16522 2 1067.625243 534.818 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3341.4 - 1.78E+06 - - - 3.5724 - 1.633 0.406 - 212.4 1 2 0 0.0038 9 0 0 0 1.98E+07 1.25E+07 - - - 3.4573 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.16523.16523.2 0.000947 18-Aug K.LLQDYGLVVR.G "sp|Q9NVH0|EXD2_HUMAN,tr|C9JLF4|C9JLF4_HUMAN" 2 1174.671 1.04 31219 16523 2 1174.672546 588.3428 Exonuclease 3'-5' domain-containing protein 2 OS=Homo sapiens OX=9606 GN=EXD2 PE=1 SV=2 5.84 3341.5 - 562696 - - - 1.3085 - 1.514 0.361 - 170.7 1 2 0 0.0015 10 0 0 0 5.47E+06 5.26E+06 - - - 2.8646 0.961 230117_WJC_METTL3_WT_vs_EV_F04.16524.16524.2 0.854 20-Jun K.LISSVDPQFLK[136.11].L "sp|Q9BVG4|PBDC1_HUMAN,tr|A6NDF3|A6NDF3_HUMAN" 2 1253.7111 6.13 31220 16524 2 1253.710271 627.8628 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 5.84 3341.6 - 468218 - - - -0.6525 - 1.028 0.128 - 76.8 1 2 0 -0.0008 11 0 0 0 2.77E+07 4.52E+06 - - - 0.0609 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.16527.16527.2 0.0103 14-Sep K.MVVLSLPR.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 913.5419 1.4 31221 16527 2 913.541006 457.7782 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.5 3342 - 825319 - - - -0.9885 - 1.48 0.32 - 274.6 1 2 0 -0.0009 8 0 0 0 2.88E+07 2.06E+07 - - - 2.5866 0.999 230117_WJC_METTL3_WT_vs_EV_F04.16529.16529.2 0.026 14-Sep R.IGVDLIMK.T "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 887.515 0.97 31223 16529 2 887.515856 444.7648 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.84 3342.2 - 1.94E+06 - - - 0.9363 - 1.394 0.316 - 150.6 1 2 0 0.0008 8 0 0 0 3.42E+07 3.53E+07 - - - 2.3765 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.16534.16534.2 0.00367 20-Oct R.VPLIGSLPEAR[166.11].L "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN,tr|K7EQG1|K7EQG1_HUMAN" 3 1160.6793 0.76 31228 16534 2 1160.680345 581.3469 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 5.97 3342.7 - 217242 - - - 0.9184 - 1.989 0.309 - 304.6 1 2 0 0.0011 11 0 0 0 3.95E+06 5.22E+06 - - - 3.1831 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.16536.16536.2 0.00844 16-Sep K.FGLFTPGSR.L "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 980.508 0.75 31229 16536 2 980.509582 491.2613 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 9.75 3342.9 - 6.34E+06 - - - 1.6481 - 1.884 0.402 - 323.6 1 2 0 0.0016 9 0 0 0 1.41E+08 1.88E+08 - - - 3.8421 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.16541.16541.2 1.76E-05 22-Nov K.VFGAAPLENVVR.K "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 1270.7034 4.08 31233 16541 2 1270.702548 636.359 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 5.97 3343.4 - 1.11E+06 - - - -0.6477 - 1.989 0.369 - 397.1 1 2 0 -0.0008 12 0 0 0 8.03E+07 1.97E+07 - - - 3.5755 0.9095 230117_WJC_METTL3_WT_vs_EV_F04.16542.16542.2 2.68 14-Jul R.DAFLTLAR.D "sp|Q92793|CBP_HUMAN,sp|Q09472|EP300_HUMAN,tr|A0A669KB12|A0A669KB12_HUMAN" 3 905.4971 2.44 31234 16542 2 905.493136 453.7558 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 5.84 3343.5 - 1.10E+06 - - - -4.3413 - 1.594 0.084 - 172.7 1 2 0 -0.0039 8 0 0 0 3.05E+07 1.25E+07 - - - 1.0664 0.9924 230117_WJC_METTL3_WT_vs_EV_F04.16558.16558.2 0.000814 20-Nov K.ALTLIAGSPLK.L "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1082.6699 0.05 31243 16558 2 1082.665907 542.3422 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 8.8 3345.4 - 1.69E+06 - - - -3.7306 - 2.155 0.284 - 391.3 1 2 0 -0.004 11 0 0 0 1.71E+07 3.61E+08 - - - 3.2144 0.9783 230117_WJC_METTL3_WT_vs_EV_F04.16569.16569.2 0.704 12-Jun R.DLIDYVR.Y "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 892.4654 2.56 31246 16569 2 892.464226 447.24 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.21 3346.9 - 1.76E+06 - - - -1.3513 - 1.123 0.186 - 175.4 1 2 0 -0.0012 7 0 0 0 7.09E+07 2.77E+07 - - - 0.782 0.9832 230117_WJC_METTL3_WT_vs_EV_F04.16581.16581.2 0.256 14-Aug K.GYGFGLIK.L "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 853.4698 1.4 31251 16581 2 853.468943 427.7422 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 3348.4 - 3.61E+06 - - - -0.9924 - 1.141 0.185 - 171 1 2 0 -0.0008 8 0 0 0 6.20E+08 4.43E+08 - - - 0.805 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.16603.16603.2 0.000134 13/24 K.VLIIGGGDGGVLR.E "sp|P19623|SPEE_HUMAN,tr|K7ESL0|K7ESL0_HUMAN" 2 1224.719 26.73 31257 16603 2 1224.718892 613.3668 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.81 3351.6 - 1.08E+06 - - - -0.1053 - 2.065 0.47 - 448.5 1 2 0 -0.0001 13 0 0 0 7.97E+07 2.98E+06 - - - 4.3734 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.16609.16609.2 0.00264 18-Sep K.IFFAGDTIPK[136.11].S "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 5 1115.6106 1.89 31259 16609 2 1115.612376 558.8126 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.84 3352.3 - 0 - - - 1.5498 - 1.598 0.346 - 184.3 1 2 0 0.0017 10 0 0 0 5.92E+07 3.14E+07 - - - 2.9044 0.998 230117_WJC_METTL3_WT_vs_EV_F04.16618.16618.2 8.88E-05 18-Sep R.LYLINSPVVR[166.11].A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1182.7 1.5 31262 16618 2 1182.6984 592.3573 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3353.6 - 2.32E+06 - - - -1.3647 - 2.015 0.274 - 312.4 1 2 0 -0.0016 10 0 0 0 3.74E+08 2.49E+08 - - - 3.0199 0.9972 230117_WJC_METTL3_WT_vs_EV_F04.16619.16619.2 8.29 18-Nov R.LYLINSPVVR.A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1172.6917 1.5 31263 16619 2 1172.689508 587.3531 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3353.7 - 2.26E+06 - - - -1.9067 - 2.02 0.271 - 545.2 1 2 0 -0.0022 10 0 0 0 3.74E+08 2.50E+08 - - - 3.0045 0.9458 230117_WJC_METTL3_WT_vs_EV_F04.16629.16629.2 0.83 14-May R.VAFTLLEK.V "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 4 919.5379 11.58 31266 16629 2 919.535661 460.7762 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 5.97 3355.2 - 384065 - - - -2.4012 - 1.217 0.189 - 66.2 10 2 0 -0.0022 8 0 0 0 6.92E+07 5.98E+06 - - - 0.5819 0.9947 230117_WJC_METTL3_WT_vs_EV_F04.16640.16640.2 0.000385 18-Aug R.GTPLISPLIK.W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1037.6485 1.78 31269 16640 2 1037.645438 519.8315 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3356.8 - 1.03E+06 - - - -2.9336 - 1.446 0.402 - 196.4 1 2 0 -0.003 10 0 0 0 2.04E+08 1.14E+08 - - - 3.0387 1 230117_WJC_METTL3_WT_vs_EV_F04.16644.16644.2 2.41E-07 22-Dec R.GYISPYFINTSK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1388.6976 4.38 31270 16644 2 1388.697479 695.3561 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3357.3 - 1.25E+06 - - - -0.0994 - 2.503 0.524 - 586.9 1 2 0 -0.0001 12 0 0 0 4.17E+07 9.53E+06 - - - 5.3253 0.9952 230117_WJC_METTL3_WT_vs_EV_F04.16653.16653.2 0.00816 12-Jun K.FTVPMLK[136.11].E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 842.4815 0.84 31274 16653 2 842.479716 422.248 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3358.5 - 413461 - - - -2.1733 - 1.435 0.324 - 110.4 1 2 0 -0.0018 7 0 0 0 4.07E+07 4.86E+07 - - - 2.5779 1 230117_WJC_METTL3_WT_vs_EV_F04.16657.16657.2 0.000789 18-Dec R.VAAAVDLIIK.S "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1011.6328 1.84 31275 16657 2 1011.625644 506.8237 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3359.1 - 2.51E+06 - - - -7.1053 - 2.583 0.471 - 462.6 1 2 0 -0.0072 10 0 0 0 8.62E+07 4.69E+07 - - - 5.1664 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.16659.16659.2 0.00322 18-Aug R.GTPLISPLIK[136.11].W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1045.6627 1.78 31277 16659 2 1045.660568 523.8386 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3359.3 - 3.43E+06 - - - -2.0217 - 1.634 0.416 - 218.6 1 2 0 -0.0021 10 0 0 0 2.03E+08 1.14E+08 - - - 3.4835 0.9893 230117_WJC_METTL3_WT_vs_EV_F04.16660.16660.2 3.05 16-Jun K.GSLLPTSPR.L "tr|H7C179|H7C179_HUMAN,tr|H7C128|H7C128_HUMAN,tr|H7C127|H7C127_HUMAN" 3 926.5185 1.42 31278 16660 2 926.51876 464.2665 Bromodomain-containing protein 8 (Fragment) OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=1 9.75 3359.4 - 903362 - - - 0.2472 - 1.192 0.162 - 84.3 2 2 0 0.0002 9 0 0 0 1.35E+08 9.53E+07 - - - 0.6111 0.9942 230117_WJC_METTL3_WT_vs_EV_F04.16662.16662.2 0.741 14-Nov K.IPLGLDLK.N "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 867.543 1.7 31279 16662 2 867.545512 434.7788 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.84 3359.6 - 0 - - - 2.9486 - 1.763 0.076 - 387.8 1 2 0 0.0026 8 0 0 0 1.22E+08 7.15E+07 - - - 1.3116 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.16671.16671.2 0.00609 12-Jun R.FFLEYDR.L "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 988.4654 1.17 31284 16671 2 988.465585 495.24 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 4.37 3360.7 - 713957 - - - 0.1548 - 1.383 0.372 - 119.1 1 2 0 0.0002 7 0 0 0 1.69E+07 1.45E+07 - - - 2.816 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.16677.16677.2 0.0758 14-Sep R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 8425.73 31287 16677 2 1000.559998 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3361.5 - 1.48E+09 - - - 0.6646 - 2.135 0.315 - 298.9 1 2 0 0.0007 8 0 0 0 4.52E+11 5.37E+07 - - - 3.6549 0.9246 230117_WJC_METTL3_WT_vs_EV_F04.16680.16680.2 3.98 16-Jun K.GSLLPTSPR[166.11].L "tr|H7C179|H7C179_HUMAN,tr|H7C128|H7C128_HUMAN,tr|H7C127|H7C127_HUMAN" 3 936.5268 1.43 31288 16680 2 936.52639 469.2707 Bromodomain-containing protein 8 (Fragment) OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=1 9.75 3361.9 - 1.49E+06 - - - -0.4389 - 1.245 0.017 - 71.4 4 2 0 -0.0004 9 0 0 0 1.36E+08 9.55E+07 - - - -0.4685 1 230117_WJC_METTL3_WT_vs_EV_F04.16681.16681.2 0.000205 13/20 R.FGGLVLSPVGK.Q sp|Q9UJK0|TSR3_HUMAN 1 1072.6281 1.19 31289 16681 2 1072.625078 537.3213 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.75 3362 - 1.12E+06 - - - -2.7997 - 2.457 0.551 - 563.5 1 2 0 -0.003 11 0 0 0 4.27E+07 3.58E+07 - - - 5.5416 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.16683.16683.2 0.0116 16-Sep K.MMLDDIVSR.G "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 6 1078.5151 1.51 31291 16683 2 1078.520547 540.2648 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.21 3362.2 - 1.27E+06 - - - 5.0486 - 1.771 0.295 - 280.5 1 2 0 0.0054 9 0 0 0 1.41E+07 9.33E+06 - - - 2.8717 1 230117_WJC_METTL3_WT_vs_EV_F04.16686.16686.2 5.45E-05 18-Oct R.YGLAAAVFTR.D sp|P30837|AL1B1_HUMAN 1 1067.5764 5.86 31292 16686 2 1067.576261 534.7955 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 8.75 3362.6 - 1.19E+06 - - - -0.1115 - 2.143 0.516 - 315.4 1 2 0 -0.0001 10 0 0 0 4.48E+07 7.66E+06 - - - 4.9797 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.16687.16687.2 0.0403 12-Aug K.FTVPMLK.E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 834.4673 0.81 31293 16687 2 834.467198 418.2409 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3362.8 - 1.14E+06 - - - -0.1786 - 1.336 0.212 - 234.1 1 2 0 -0.0001 7 0 0 0 3.57E+07 4.39E+07 - - - 1.5247 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.16698.16698.2 0.000236 20-Nov R.FGGLVLSPVGK[136.11].Q sp|Q9UJK0|TSR3_HUMAN 1 1080.6423 1.27 31299 16698 2 1080.643384 541.3284 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.75 3364.1 - 497268 - - - 1.0207 - 2.013 0.443 - 395.6 1 2 0 0.0011 11 0 0 0 4.26E+07 3.36E+07 - - - 4.2053 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.16699.16699.2 0.141 14-Jul R.QVFLATWK.D "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 991.5491 0 31300 16699 2 991.549188 496.7818 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.75 3364.3 - 539233 - - - 0.0867 - 1.243 0.23 - 133.9 1 2 0 0.0001 8 0 0 0 6.10E+06 1.29E+10 - - - 1.3958 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.16701.16701.2 0.135 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.08 31302 16701 2 1235.759925 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3364.5 - 359002 - - - -0.1885 - 1.706 0.352 - 242.6 1 2 0 -0.0002 11 0 0 0 5.45E+07 5.07E+07 - - - 3.0858 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.16709.16709.2 0.311 20-Jul K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.08 31307 16709 2 1245.767941 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3365.5 - 3.44E+06 - - - -0.3909 - 1.559 0.263 - 154 1 2 0 -0.0005 11 0 0 0 5.45E+07 5.07E+07 - - - 2.1846 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.16718.16718.2 0.00359 16-Dec K.LLC[160.03]GLLAER[166.11].L sp|P14174|MIF_HUMAN 1 1053.588 0.89 31313 16718 2 1053.587724 527.8013 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3366.5 - 1.07E+07 - - - -0.2819 - 2.129 0.267 - 470.3 1 2 0 -0.0003 9 0 0 0 8.40E+08 9.43E+08 - - - 3.1991 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.16719.16719.2 0.00141 16-Oct K.LLC[160.03]GLLAER.L sp|P14174|MIF_HUMAN 1 1043.5798 0.88 31314 16719 2 1043.580018 522.7972 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3366.6 - 7.24E+06 - - - 0.2559 - 2.103 0.36 - 307.1 1 2 0 0.0003 9 0 0 0 8.42E+08 9.54E+08 - - - 3.8505 0.994 230117_WJC_METTL3_WT_vs_EV_F04.16721.16721.2 0.611 12-Jul R.ILLQYLK.Q "sp|Q9P0U3|SENP1_HUMAN,sp|Q9NVH2|INT7_HUMAN" 2 889.5637 5.2 31316 16721 2 889.564163 445.7891 Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2 8.59 3366.9 - 2.55E+06 - - - 0.5317 - 1.31 0.143 - 144.3 1 2 0 0.0005 7 0 0 0 2.44E+07 4.68E+06 - - - 0.9526 0.9763 230117_WJC_METTL3_WT_vs_EV_F04.16723.16723.2 0.115 12-Jun R.FVAELWK[136.11].D sp|P35580|MYH10_HUMAN 1 899.4996 0.76 31318 16723 2 899.497388 450.7571 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3367.1 - 1.94E+06 - - - -2.5036 - 1.32 0.183 - 112.8 1 2 0 -0.0023 7 0 0 0 4.21E+07 5.52E+07 - - - 1.2716 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.16730.16730.2 0.0173 16-Aug R.GLFTGLTPR.L "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 960.5393 1.07 31323 16730 2 960.539116 481.2769 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3367.8 - 963619 - - - -0.1562 - 1.473 0.241 - 193.5 1 2 0 -0.0001 9 0 0 0 3.55E+07 3.31E+07 - - - 1.9415 0.999 230117_WJC_METTL3_WT_vs_EV_F04.16731.16731.2 0.0176 16-Sep R.YVANLFPYK.G "sp|Q15181|IPYR_HUMAN,sp|Q9H2U2|IPYR2_HUMAN,tr|D6RGV9|D6RGV9_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN,tr|D6RGI1|D6RGI1_HUMAN,tr|H0YAK2|H0YAK2_HUMAN" 7 1113.5859 2.35 31324 16731 2 1113.587309 557.8002 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 8.5 3367.9 - 840487 - - - 1.2814 - 1.3 0.35 - 171.3 1 2 0 0.0014 9 0 0 0 6.29E+07 2.68E+07 - - - 2.3847 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.16740.16740.2 0.157 12-Jul K.LMIWDTR.S "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 933.4742 1.48 31331 16740 2 933.475797 467.7444 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3369 - 8.65E+06 - - - 1.6862 - 1.45 0.341 - 288.4 1 2 0 0.0016 7 0 0 0 1.65E+08 1.12E+08 - - - 2.7365 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.16741.16741.2 0.0423 16-Sep R.GLFTGLTPR[166.11].L "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 970.5475 1.05 31332 16741 2 970.548234 486.281 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3369.2 - 1.58E+06 - - - 0.7192 - 1.964 0.324 - 230.3 1 2 0 0.0007 9 0 0 0 3.54E+07 3.35E+07 - - - 3.3866 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.16743.16743.2 0.000674 18-Oct K.VYVIGSFVDK[136.11].S sp|Q7L0Y3|TM10C_HUMAN 1 1133.6212 0.8 31334 16743 2 1133.622721 567.8179 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3369.4 - 1.62E+06 - - - 1.332 - 2.022 0.481 - 344.9 1 2 0 0.0015 10 0 0 0 1.94E+07 2.42E+07 - - - 4.5585 1 230117_WJC_METTL3_WT_vs_EV_F04.16744.16744.2 1.74E-05 18-Dec K.VYVIGSFVDK.S sp|Q7L0Y3|TM10C_HUMAN 1 1125.607 0.8 31335 16744 2 1125.610557 563.8108 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3369.5 - 1.41E+06 - - - 3.1503 - 2.558 0.426 - 488.7 1 2 0 0.0035 10 0 0 0 1.94E+07 2.42E+07 - - - 4.808 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.16745.16745.2 0.0328 18-Sep K.APGLGLVLER.V "sp|Q9Y606|TRUA_HUMAN,tr|G8JLB3|G8JLB3_HUMAN,tr|F5H1S9|F5H1S9_HUMAN" 3 1023.6077 1.73 31336 16745 2 1023.607632 512.8111 tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3 6.05 3369.5 - 1.27E+06 - - - -0.0469 - 1.889 0.305 - 197.2 1 2 0 0 10 0 0 0 2.99E+07 1.73E+07 - - - 3.0691 0.9949 230117_WJC_METTL3_WT_vs_EV_F04.16747.16747.2 1.23 12-Jun R.GFELTFK[136.11].T "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 848.4524 1.54 31338 16747 2 848.453855 425.2335 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3369.8 - 974555 - - - 1.7679 - 1.199 0.187 - 135.4 1 2 0 0.0015 7 0 0 0 5.23E+07 3.41E+07 - - - 0.9968 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.16750.16750.2 0.000311 16-Oct K.FLGELYNYR[166.11].M sp|Q9HAU5|RENT2_HUMAN 1 1183.5901 0.81 31341 16750 2 1183.592855 592.8023 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 6 3370.2 - 485764 - - - 2.3032 - 1.693 0.382 - 337.8 1 2 0 0.0027 9 0 0 0 5.31E+06 6.58E+06 - - - 3.3848 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.16754.16754.2 0.00888 22-Sep R.VLIGNVQPGILR.F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1277.782 2.71 31345 16754 2 1277.786112 639.8983 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3370.7 - 288183 - - - 3.2525 - 2.03 0.345 - 280.9 1 2 0 0.0042 12 0 0 0 7.06E+06 2.61E+06 - - - 3.4508 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.16759.16759.2 0.0125 13/20 R.ALDEGDIALLK.T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1156.634 2.62 31348 16759 2 1156.63519 579.3243 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 3371.3 - 1.96E+06 - - - 1.0686 - 1.279 0.329 - 219.7 1 2 0 0.0012 11 0 0 0 1.55E+07 5.91E+06 - - - 2.1363 0.996 230117_WJC_METTL3_WT_vs_EV_F04.16761.16761.2 2.15 12-Aug R.LTLLQLK.G sp|Q8NHP8|PLBL2_HUMAN 1 827.548 1.12 31350 16761 2 827.548941 414.7813 Putative phospholipase B-like 2 OS=Homo sapiens OX=9606 GN=PLBD2 PE=1 SV=2 8.75 3371.5 - 2.88E+06 - - - 1.0888 - 1.523 0.106 - 166.2 1 2 0 0.0009 7 0 0 0 2.07E+07 1.86E+07 - - - 1.1566 0.8887 230117_WJC_METTL3_WT_vs_EV_F04.16763.16763.2 4.61 14-Apr K.LEPDILLR[166.11].A "sp|Q01433|AMPD2_HUMAN,tr|A0A7P0TB79|A0A7P0TB79_HUMAN,tr|A0A590UK85|A0A590UK85_HUMAN,tr|A0A5F9UK94|A0A5F9UK94_HUMAN,tr|E9PJF6|E9PJF6_HUMAN,tr|A0A590UJX5|A0A590UJX5_HUMAN,tr|H0Y360|H0Y360_HUMAN,tr|A0A7P0Z4H6|A0A7P0Z4H6_HUMAN,tr|E9PIJ1|E9PIJ1_HUMAN,tr|H0YF16|H0YF16_HUMAN,tr|A0A804CCZ3|A0A804CCZ3_HUMAN" 11 977.5785 2.75 31352 16763 2 977.58179 489.7965 AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2 4.37 3371.8 - 667692 - - - 3.3634 - 1.035 0.117 - 29.7 25 2 0 0.0033 8 0 0 0 1.25E+07 4.53E+06 - - - -0.6166 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.16764.16764.2 0.0244 22-Jul R.VLIGNVQPGILR[166.11].F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1287.7902 2.71 31353 16764 2 1287.791766 644.9024 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3371.9 - 507140 - - - 1.1958 - 1.526 0.284 - 105.7 1 2 0 0.0015 12 0 0 0 7.06E+06 2.61E+06 - - - 2.2502 0.8768 230117_WJC_METTL3_WT_vs_EV_F04.16767.16767.2 1.88 22-Apr R.MPGSVIPPPLVR.G sp|Q86YP4|P66A_HUMAN 1 1261.7217 4.89 31356 16767 2 1261.721274 631.8681 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.5 3372.3 - 229797 - - - -0.3091 - 1.084 0.037 - 49.2 7 2 0 -0.0004 12 0 0 0 2.36E+06 4.83E+05 - - - -0.8511 1 230117_WJC_METTL3_WT_vs_EV_F04.16772.16772.2 3.36E-05 20-Dec R.ALDEGDIALLK[136.11].T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1164.6482 2.7 31359 16772 2 1164.64985 583.3314 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 3373 - 348004 - - - 1.4562 - 2.499 0.516 - 309.5 1 2 0 0.0017 11 0 0 0 1.60E+07 5.91E+06 - - - 5.3293 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.16773.16773.2 0.326 14-Aug R.ILELDQFK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1012.5684 1.23 31360 16773 2 1012.570145 507.2915 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3373 - 6.60E+06 - - - 1.6769 - 1.649 0.301 - 150.6 1 2 0 0.0017 8 0 0 0 3.20E+08 2.60E+08 - - - 2.7721 0.9742 230117_WJC_METTL3_WT_vs_EV_F04.16775.16775.2 0.167 16-Jul K.YFLGQSVLR.S "sp|Q9Y255|PRLD1_HUMAN,tr|D6REW1|D6REW1_HUMAN,tr|D6RC47|D6RC47_HUMAN" 3 1081.592 1.36 31362 16775 2 1081.589259 541.8033 "PRELI domain-containing protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=PRELID1 PE=1 SV=1" 8.75 3373.2 - 501138 - - - -2.562 - 1.277 0.201 - 102.5 1 2 0 -0.0028 9 0 0 0 1.06E+07 7.79E+06 - - - 1.2321 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.16777.16777.2 0.00165 20-Jul R.ALAAQLPVLPR.S "sp|Q96GK7|FAH2A_HUMAN,tr|C9JGM0|C9JGM0_HUMAN" 2 1147.7077 2.14 31364 16777 2 1147.707849 574.8611 Fumarylacetoacetate hydrolase domain-containing protein 2A OS=Homo sapiens OX=9606 GN=FAHD2A PE=1 SV=1 9.79 3373.5 - 294229 - - - 0.1054 - 1.72 0.334 - 111 1 2 0 0.0001 11 0 0 0 5.80E+06 2.70E+06 - - - 2.975 0.996 230117_WJC_METTL3_WT_vs_EV_F04.16784.16784.2 0.0076 12-Aug K.LDDLFLK.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 862.48 0.87 31369 16784 2 862.481154 432.2473 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3374.3 - 4.01E+06 - - - 1.3148 - 1.743 0.046 - 224.7 1 2 0 0.0011 7 0 0 0 1.13E+08 1.29E+08 - - - 1.1409 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.16785.16785.2 0.00732 18-Oct R.FGVITEVDIK.R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1119.6176 1.13 31370 16785 2 1119.618797 560.8161 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 4.37 3374.4 - 818959 - - - 1.0906 - 2.238 0.381 - 350.8 1 2 0 0.0012 10 0 0 0 1.43E+07 1.27E+07 - - - 4.1033 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.16791.16791.2 0.0965 14-Aug R.ILELDQFK.G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1004.5542 1.03 31374 16791 2 1004.558246 503.2844 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3375.2 - 5.16E+06 - - - 3.9809 - 1.77 0.336 - 159.6 1 2 0 0.004 8 0 0 0 2.67E+08 2.58E+08 - - - 3.2435 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.16792.16792.2 0.00648 16-Aug K.IDPEAFITR[166.11].H sp|Q92616|GCN1_HUMAN 1 1070.5636 1.21 31375 16792 2 1070.561424 536.2891 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3375.3 - 269708 - - - -2.0139 - 1.474 0.368 - 141.9 1 2 0 -0.0022 9 0 0 0 3.07E+07 2.54E+07 - - - 2.8808 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.16797.16797.2 1.02 14-Aug R.VWDISGLR[166.11].K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 954.5162 3.23 31378 16797 2 954.51659 478.2654 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3376 - 635154 - - - 0.3709 - 1.869 0.165 - 200.1 1 2 0 0.0004 8 0 0 0 7.52E+07 2.33E+07 - - - 2.1458 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.16799.16799.2 0.197 20-Oct K.LLAAFPGVTPR.V "sp|Q9Y2I1|NISCH_HUMAN,tr|C9J715|C9J715_HUMAN" 2 1140.6655 2.96 31380 16799 2 1140.665343 571.34 Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3 9.75 3376.2 - 208224 - - - -0.1631 - 1.764 0.191 - 226.6 1 2 0 -0.0002 11 0 0 0 9.42E+06 3.18E+06 - - - 1.9871 0.9801 230117_WJC_METTL3_WT_vs_EV_F04.16809.16809.2 0.00965 14-Jul R.VWDISGLR.K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 944.508 3.24 31386 16809 2 944.513899 473.2613 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3377.5 - 2.89E+06 - - - 6.2816 - 1.701 0.209 - 216 1 2 0 0.0059 8 0 0 0 7.55E+07 2.33E+07 - - - 2.1849 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.16811.16811.2 0.00118 14-Aug K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 0.81 31388 16811 2 988.573692 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3377.6 - 1.50E+06 - - - 3.1621 - 1.696 0.405 - 285 1 2 0 0.0031 8 0 0 0 4.24E+09 5.25E+09 - - - 3.6246 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.16812.16812.2 0.0336 18-Nov R.ALEAELAALR[166.11].Q sp|Q16352|AINX_HUMAN 1 1065.6058 5.25 31389 16812 2 1065.609367 533.8102 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.53 3377.7 - 1.23E+06 - - - 3.3671 - 1.809 0.287 - 444.8 1 2 0 0.0036 10 0 0 0 2.76E+08 5.26E+07 - - - 2.8143 0.9878 230117_WJC_METTL3_WT_vs_EV_F04.16813.16813.2 0.0238 14-Aug K.VITLC[160.03]LYR.D sp|Q10570|CPSF1_HUMAN 1 1036.5739 0.28 31390 16813 2 1036.577407 519.2942 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.19 3377.8 - 1.05E+06 - - - 3.3476 - 1.487 0.092 - 191 1 2 0 0.0035 8 0 0 0 1.47E+07 5.14E+07 - - - 0.916 0.9803 230117_WJC_METTL3_WT_vs_EV_F04.16814.16814.2 8.41 14-Jun K.LEPDILLR.A "sp|Q01433|AMPD2_HUMAN,tr|A0A7P0TB79|A0A7P0TB79_HUMAN,tr|A0A590UK85|A0A590UK85_HUMAN,tr|A0A5F9UK94|A0A5F9UK94_HUMAN,tr|E9PJF6|E9PJF6_HUMAN,tr|A0A590UJX5|A0A590UJX5_HUMAN,tr|H0Y360|H0Y360_HUMAN,tr|A0A7P0Z4H6|A0A7P0Z4H6_HUMAN,tr|E9PIJ1|E9PIJ1_HUMAN,tr|H0YF16|H0YF16_HUMAN,tr|A0A804CCZ3|A0A804CCZ3_HUMAN" 11 967.5702 2.75 31391 16814 2 967.571782 484.7924 AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2 4.37 3377.9 - 446827 - - - 1.602 - 1.167 0.088 - 93.9 2 2 0 0.0015 8 0 0 0 1.25E+07 4.53E+06 - - - 0.0218 0.9895 230117_WJC_METTL3_WT_vs_EV_F04.16816.16816.2 0.00323 18-Sep K.IVAFENAFER[166.11].L sp|O60763|USO1_HUMAN 1 1204.6116 0.85 31393 16816 2 1204.61805 603.3131 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 3378.1 - 363362 - - - 5.3602 - 1.247 0.347 - 168 1 2 0 0.0065 10 0 0 0 5.77E+06 6.76E+06 - - - 2.2181 0.9862 230117_WJC_METTL3_WT_vs_EV_F04.16818.16818.2 0.073 20-Jun R.LYPEGLAQLAR.A "sp|P61421|VA0D1_HUMAN,tr|J3QL14|J3QL14_HUMAN,tr|F5GYQ1|F5GYQ1_HUMAN,tr|R4GN72|R4GN72_HUMAN" 4 1229.6768 1.39 31395 16818 2 1229.678929 615.8457 V-type proton ATPase subunit d 1 OS=Homo sapiens OX=9606 GN=ATP6V0D1 PE=1 SV=1 6 3378.4 - 149699 - - - 1.7135 - 1.161 0.112 - 93.9 1 2 0 0.0021 11 0 0 0 1.38E+07 9.94E+06 - - - 0.2714 0.9933 230117_WJC_METTL3_WT_vs_EV_F04.16821.16821.2 0.026 12-Jun K.FIDPFC[160.03]K.L sp|Q14684|RRP1B_HUMAN 1 925.4368 3.42 31396 16821 2 925.441285 463.7257 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.83 3378.8 - 1.10E+06 - - - 4.8734 - 1.193 0.37 - 102.4 1 2 0 0.0045 7 0 0 0 3.03E+07 8.85E+06 - - - 2.3316 0.9932 230117_WJC_METTL3_WT_vs_EV_F04.16826.16826.2 0.000298 18-Jul K.IVAFENAFER.L sp|O60763|USO1_HUMAN 1 1194.6033 0.85 31401 16826 2 1194.609723 598.3089 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 3379.2 - 365275 - - - 5.3574 - 1.649 0.303 - 92.8 1 2 0 0.0064 10 0 0 0 5.74E+06 6.76E+06 - - - 2.6731 0.995 230117_WJC_METTL3_WT_vs_EV_F04.16829.16829.2 0.000915 20-Sep R.LYPEGLAQLAR.A "sp|P61421|VA0D1_HUMAN,tr|J3QL14|J3QL14_HUMAN,tr|F5GYQ1|F5GYQ1_HUMAN,tr|R4GN72|R4GN72_HUMAN" 4 1229.6768 1.39 31404 16829 2 1229.681799 615.8457 V-type proton ATPase subunit d 1 OS=Homo sapiens OX=9606 GN=ATP6V0D1 PE=1 SV=1 6 3379.6 - 155992 - - - 4.0474 - 1.607 0.235 - 242.2 1 2 0 0.005 11 0 0 0 1.38E+07 9.94E+06 - - - 2.0584 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.16834.16834.2 0.0223 14-Jul K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 0.81 31407 16834 2 998.583002 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3380.3 - 1.79E+07 - - - 4.1719 - 1.597 0.325 - 216.1 1 2 0 0.0042 8 0 0 0 4.24E+09 5.25E+09 - - - 2.852 0.9954 230117_WJC_METTL3_WT_vs_EV_F04.16835.16835.2 1.19 14-Jul R.DILLQGLK[136.11].A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 906.563 0.85 31408 16835 2 906.565602 454.2888 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3380.4 - 662480 - - - 2.9055 - 1.476 0.17 - 124.2 1 2 0 0.0026 8 0 0 0 1.94E+07 2.27E+07 - - - 1.47 0.9611 230117_WJC_METTL3_WT_vs_EV_F04.16843.16843.2 15.6 14-May R.DILLQGLK.A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 898.5488 0.86 31414 16843 2 898.550175 450.2817 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3381.3 - 858361 - - - 1.5659 - 0.976 0.111 - 63.6 3 2 0 0.0014 8 0 0 0 1.95E+07 2.27E+07 - - - -0.426 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.16844.16844.2 0.00518 18-Sep R.VIAIDIDPVK[136.11].L sp|Q96RS0|TGS1_HUMAN 1 1089.6525 1.99 31415 16844 2 1089.653249 545.8335 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 4.21 3381.3 - 988078 - - - 0.6773 - 1.632 0.214 - 204.5 1 2 0 0.0007 10 0 0 0 2.76E+07 1.38E+07 - - - 1.9886 1 230117_WJC_METTL3_WT_vs_EV_F04.16847.16847.3 1.72E-06 15/64 K.MLQAPESVLAEHYQDLR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 2008.9916 0.7 31418 16847 3 2008.995801 670.6711 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3381.7 - 492184 - - - 2.1006 - 3.339 0.533 - 165.3 1 2 0 0.0042 17 0 0 0 3.30E+06 4.72E+06 - - - 7.5271 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.16849.16849.2 0.000311 20-Sep R.LYPEGLAQLAR[166.11].A "sp|P61421|VA0D1_HUMAN,tr|J3QL14|J3QL14_HUMAN,tr|F5GYQ1|F5GYQ1_HUMAN,tr|R4GN72|R4GN72_HUMAN" 4 1239.6851 1.42 31420 16849 2 1239.686139 620.8498 V-type proton ATPase subunit d 1 OS=Homo sapiens OX=9606 GN=ATP6V0D1 PE=1 SV=1 6 3381.9 - 326308 - - - 0.8446 - 1.452 0.396 - 177.1 1 2 0 0.001 11 0 0 0 1.38E+07 9.71E+06 - - - 2.9744 0.9954 230117_WJC_METTL3_WT_vs_EV_F04.16854.16854.2 0.0235 12-Jul R.IPTAWFR.E "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN" 2 889.481 2.44 31423 16854 2 889.479933 445.7478 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 9.75 3382.5 - 1.65E+06 - - - -1.2254 - 1.307 0.286 - 157.9 1 2 0 -0.0011 7 0 0 0 1.22E+07 4.99E+06 - - - 2.0014 0.8881 230117_WJC_METTL3_WT_vs_EV_F04.16856.16856.2 0.869 22-Sep -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 1.57 31425 16856 2 1306.763731 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3382.7 - 904148 - - - -3.4811 - 1.318 0.118 - 97.1 2 2 0 -0.0045 12 0 0 0 2.71E+07 1.73E+07 - - - 0.5032 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.16857.16857.2 0.225 22-Aug -.MVPPVQVSPLIK[136.11].L sp|P56385|ATP5I_HUMAN 1 1314.7825 1.57 31426 16857 2 1314.781636 658.3985 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3382.9 - 573255 - - - -0.6419 - 1.534 0.241 - 80.3 1 2 0 -0.0008 12 0 0 0 2.81E+07 1.79E+07 - - - 1.9466 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.16858.16858.2 0.0101 18-Oct R.LLLNNDNLLR[166.11].E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1206.696 1.49 31427 16858 2 1206.698145 604.3553 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3383 - 562598 - - - 1.785 - 2.216 0.41 - 292.1 1 2 0 0.0022 10 0 0 0 3.08E+08 2.07E+08 - - - 4.2896 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.16860.16860.2 0.00147 18-Sep K.IEDMAVSLIR[166.11].E sp|Q15776|ZKSC8_HUMAN 1 1155.6197 1.1 31429 16860 2 1155.619545 578.8171 Zinc finger protein with KRAB and SCAN domains 8 OS=Homo sapiens OX=9606 GN=ZKSCAN8 PE=1 SV=2 4.37 3383.3 - 334452 - - - -0.1471 - 1.761 0.356 - 176.5 1 2 0 -0.0002 10 0 0 0 5.50E+06 4.99E+06 - - - 3.2499 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.16865.16865.2 0.00635 18-Sep R.LLLNNDNLLR.E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1196.6877 1.49 31431 16865 2 1196.69213 599.3511 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3383.9 - 1.87E+06 - - - 3.6843 - 2.084 0.386 - 228.9 1 2 0 0.0044 10 0 0 0 3.08E+08 2.07E+08 - - - 3.9402 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.16866.16866.2 0.036 14-Aug R.LELSVLYK.E "sp|Q96FW1|OTUB1_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 5 963.5641 2.73 31432 16866 2 963.566409 482.7893 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 6 3384 - 801777 - - - 2.4129 - 1.823 0.287 - 164.4 1 2 0 0.0023 8 0 0 0 2.88E+07 1.05E+07 - - - 2.9711 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.16867.16867.2 0.00146 16-Aug K.IDPEAFITR.H sp|Q92616|GCN1_HUMAN 1 1060.5553 1.18 31433 16867 2 1060.554496 531.2849 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3384.1 - 1.76E+06 - - - -0.7675 - 1.691 0.283 - 203.9 1 2 0 -0.0008 9 0 0 0 3.12E+07 2.64E+07 - - - 2.6508 0.9896 230117_WJC_METTL3_WT_vs_EV_F04.16868.16868.2 0.34 14-Aug K.LPLDVLGR[166.11].V "sp|Q9UBC2|EP15R_HUMAN,tr|M0R2S2|M0R2S2_HUMAN,tr|M0R165|M0R165_HUMAN" 3 891.5417 2.61 31434 16868 2 891.540944 446.7781 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 5.84 3384.3 - 1.43E+06 - - - -0.8726 - 1.383 0.148 - 194.9 1 2 0 -0.0008 8 0 0 0 4.38E+07 1.68E+07 - - - 1.1118 1 230117_WJC_METTL3_WT_vs_EV_F04.16869.16869.2 4.53E-06 18-Oct K.C[160.03]LEPTVALLR[166.11].W "sp|Q8TCG1|CIP2A_HUMAN,tr|A0A087X211|A0A087X211_HUMAN" 2 1180.6514 1.83 31435 16869 2 1180.651729 591.333 Protein CIP2A OS=Homo sapiens OX=9606 GN=CIP2A PE=1 SV=2 5.99 3384.4 - 1.05E+06 - - - 0.321 - 2.08 0.488 - 325.9 1 2 0 0.0004 10 0 0 0 1.55E+07 8.47E+06 - - - 4.6895 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.16870.16870.2 0.0348 18-Oct K.IEDMAVSLIR.E sp|Q15776|ZKSC8_HUMAN 1 1145.6114 1.1 31436 16870 2 1145.617619 573.813 Zinc finger protein with KRAB and SCAN domains 8 OS=Homo sapiens OX=9606 GN=ZKSCAN8 PE=1 SV=2 4.37 3384.5 - 778075 - - - 5.3893 - 2.019 0.322 - 247.2 1 2 0 0.0062 10 0 0 0 5.50E+06 4.99E+06 - - - 3.3785 0.9961 230117_WJC_METTL3_WT_vs_EV_F04.16873.16873.2 0.000348 20-Nov R.FDLALAATEAR[166.11].Q sp|Q6PD62|CTR9_HUMAN 1 1186.6222 2.93 31439 16873 2 1186.617868 594.3184 RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1 4.37 3384.9 - 491700 - - - -3.6153 - 2.471 0.385 - 354.1 1 2 0 -0.0043 11 0 0 0 9.41E+06 3.22E+06 - - - 4.3305 1 230117_WJC_METTL3_WT_vs_EV_F04.16875.16875.2 3.26E-06 26-Sep R.EAGNINQSLLTLGR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1494.803 0.18 31441 16875 2 1494.798278 748.4088 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.1 3385.2 - 216843 - - - -3.1429 - 2.344 0.488 - 216 1 2 0 -0.0047 14 0 0 0 4.39E+05 2.46E+06 - - - 4.7816 0.9913 230117_WJC_METTL3_WT_vs_EV_F04.16881.16881.2 0.148 12-Jun K.VLLPFTR.A sp|Q8TEM1|PO210_HUMAN 1 844.5171 2.09 31444 16881 2 844.518553 423.2658 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 9.72 3385.9 - 1.85E+06 - - - 1.7513 - 1.328 0.089 - 121.2 1 2 0 0.0015 7 0 0 0 5.47E+07 2.62E+07 - - - 0.5967 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.16882.16882.2 0.224 14-Jun K.YVVGLIIK[136.11].T "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 911.5935 1.42 31445 16882 2 911.594517 456.804 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3386.1 - 2.11E+06 - - - 1.0717 - 1.278 0.314 - 103.8 1 2 0 0.001 8 0 0 0 4.62E+07 3.25E+07 - - - 2.0997 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.16883.16883.2 0.00152 18-Sep K.AVFVPDIYSR.T sp|O94874|UFL1_HUMAN 1 1165.6132 1.57 31446 16883 2 1165.61316 583.8139 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.88 3386.2 - 634886 - - - 0.0009 - 1.973 0.409 - 318.5 1 2 0 0 10 0 0 0 1.09E+07 6.92E+06 - - - 3.9587 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.16885.16885.2 0.000759 28-Nov R.SDGALLLGASSLSGR[166.11].C sp|Q9BQA1|MEP50_HUMAN 1 1412.7499 0.57 31448 16885 2 1412.746558 707.3822 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.55 3386.5 - 224460 - - - -2.3493 - 2.303 0.44 - 237.1 1 2 0 -0.0033 15 0 0 0 1.91E+06 3.36E+06 - - - 4.3407 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.16894.16894.2 0.0267 14-Jul K.YVVGLIIK.T "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 903.5793 1.42 31453 16894 2 903.579735 452.7969 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3387.5 - 2.91E+06 - - - 0.4372 - 1.205 0.304 - 146.5 1 2 0 0.0004 8 0 0 0 4.62E+07 3.25E+07 - - - 1.8486 0.998 230117_WJC_METTL3_WT_vs_EV_F04.16895.16895.2 0.386 12-Jul R.LLQLWEK[136.11].N "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 936.5524 1.35 31454 16895 2 936.552589 469.2835 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 6 3387.5 - 934801 - - - 0.1986 - 1.446 0.239 - 118.5 1 2 0 0.0002 7 0 0 0 7.23E+07 5.36E+07 - - - 1.9748 1 230117_WJC_METTL3_WT_vs_EV_F04.16896.16896.2 5.45E-06 24-Oct R.ILGVGPDDPDLVR.A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1364.73 2.49 31455 16896 2 1364.729585 683.3723 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3387.7 - 727991 - - - -0.2894 - 2.195 0.5 - 329.5 1 2 0 -0.0004 13 0 0 0 6.71E+06 2.70E+06 - - - 4.7516 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.16897.16897.2 0.000954 18-Aug K.AVFVPDIYSR[166.11].T sp|O94874|UFL1_HUMAN 1 1175.6214 1.59 31456 16897 2 1175.62146 588.818 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.88 3387.8 - 383144 - - - 0.0264 - 1.792 0.349 - 221.9 1 2 0 0 10 0 0 0 1.10E+07 6.92E+06 - - - 3.247 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.16900.16900.2 0.0138 16-Sep K.LFSELPLAK.K "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1016.5906 1.22 31457 16900 2 1016.588658 509.3026 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 6 3388.2 - 2.88E+06 - - - -1.9428 - 1.644 0.379 - 233.3 1 2 0 -0.002 9 0 0 0 1.38E+08 1.13E+08 - - - 3.2779 0.9801 230117_WJC_METTL3_WT_vs_EV_F04.16902.16902.2 2.14 14-May R.LMGDYLLR.G "sp|O60232|ZNRD2_HUMAN,tr|H0YEK1|H0YEK1_HUMAN,tr|E9PK41|E9PK41_HUMAN,tr|H0YEB6|H0YEB6_HUMAN" 4 979.5161 4.21 31459 16902 2 979.520942 490.7653 Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1 5.84 3388.5 - 906227 - - - 4.9555 - 1.236 0.267 - 51.4 4 2 0 0.0049 8 0 0 0 2.85E+07 6.76E+06 - - - 1.3816 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.16903.16903.2 0.00269 22-Dec K.ALLTPVAIAAGR.K sp|P00390|GSHR_HUMAN 1 1151.7026 3.19 31460 16903 2 1151.703283 576.8586 "Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2" 9.79 3388.6 - 857360 - - - 0.5557 - 2.488 0.338 - 431.5 1 2 0 0.0006 12 0 0 0 4.54E+07 1.42E+07 - - - 3.9355 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.16907.16907.2 9.13E-05 24-Sep R.ILGVGPDDPDLVR[166.11].A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1374.7383 2.49 31464 16907 2 1374.743362 688.3764 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3389.1 - 210585 - - - 3.7185 - 2.024 0.441 - 268 1 2 0 0.0051 13 0 0 0 6.71E+06 2.70E+06 - - - 4.1062 0.994 230117_WJC_METTL3_WT_vs_EV_F04.16914.16914.2 0.00601 18-Aug R.LLYEALVDC[160.03]K[136.11].K "sp|Q7L2H7|EIF3M_HUMAN,tr|J3KNJ2|J3KNJ2_HUMAN,tr|E9PRY0|E9PRY0_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 4 1230.641 1.09 31469 16914 2 1230.636349 616.3278 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 4.37 3390 - 599512 - - - -3.7476 - 1.742 0.408 - 186.5 1 2 0 -0.0046 10 0 0 0 5.62E+06 5.17E+06 - - - 3.6023 0.9905 230117_WJC_METTL3_WT_vs_EV_F04.16922.16922.2 0.0684 16-Jul R.LLVAVLTSR.A "sp|Q9P2E5|CHPF2_HUMAN,tr|G5E9W2|G5E9W2_HUMAN,tr|C9JZF7|C9JZF7_HUMAN" 3 970.6175 0.97 31475 16922 2 970.619561 486.316 Chondroitin sulfate glucuronyltransferase OS=Homo sapiens OX=9606 GN=CHPF2 PE=2 SV=2 9.75 3390.8 - 376091 - - - 2.1069 - 1.5 0.072 - 108.6 2 2 0 0.002 9 0 0 0 4.67E+06 4.82E+06 - - - 0.6107 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.16925.16925.2 0.00372 18-Nov R.LGLSTLGELK.Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1029.607 2.6 31476 16925 2 1029.608925 515.8108 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3391.2 - 2.10E+06 - - - 1.859 - 1.946 0.297 - 231.6 1 2 0 0.0019 10 0 0 0 2.86E+08 1.10E+08 - - - 3.0924 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.16926.16926.2 0.000902 18-Oct R.LGLSTLGELK[136.11].Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1037.6212 2.6 31477 16926 2 1037.622206 519.8179 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3391.3 - 908819 - - - 0.9589 - 1.92 0.374 - 154.6 1 2 0 0.001 10 0 0 0 2.86E+08 1.10E+08 - - - 3.6239 0.999 230117_WJC_METTL3_WT_vs_EV_F04.16929.16929.2 0.0327 14-Oct K.MFAEIMMK[136.11].L "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1007.4734 1.02 31480 16929 2 1007.476718 504.744 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 5.75 3391.5 - 1.16E+06 - - - 3.3261 - 2.005 0.314 - 342 1 2 0 0.0034 8 0 0 0 1.71E+07 1.68E+07 - - - 3.4572 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.16932.16932.2 0.000665 18-Nov K.VFEVMLATDR[166.11].S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1189.6041 1.76 31483 16932 2 1189.606235 595.8093 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3391.9 - 123018 - - - 1.8241 - 2.25 0.405 - 485.1 1 2 0 0.0022 10 0 0 0 2.20E+07 1.25E+07 - - - 4.2952 0.9948 230117_WJC_METTL3_WT_vs_EV_F04.16940.16940.2 0.195 12-Aug R.IQLFLAR[166.11].L "sp|Q96FV9|THOC1_HUMAN,tr|A0A087WWS1|A0A087WWS1_HUMAN,tr|A0A087WY84|A0A087WY84_HUMAN,tr|J3KT14|J3KT14_HUMAN" 4 869.5362 0.47 31489 16940 2 869.537268 435.7754 THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1 9.75 3392.7 - 893309 - - - 1.1788 - 1.812 0.004 - 185.1 1 2 0 0.001 7 0 0 0 9.52E+06 2.02E+07 - - - 0.9537 1 230117_WJC_METTL3_WT_vs_EV_F04.16941.16941.2 0.00023 18-Dec K.VFEVMLATDR.S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1179.5958 1.78 31490 16941 2 1179.596353 590.8052 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3392.9 - 562519 - - - 0.473 - 2.355 0.473 - 698.3 1 2 0 0.0006 10 0 0 0 2.19E+07 1.23E+07 - - - 4.9253 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.16942.16942.2 0.135 14-Aug K.GLLTPIIK[136.11].D "sp|O00330|ODPX_HUMAN,tr|H0YD97|H0YD97_HUMAN" 2 861.5779 1.71 31491 16942 2 861.579119 431.7962 "Pyruvate dehydrogenase protein X component, mitochondrial OS=Homo sapiens OX=9606 GN=PDHX PE=1 SV=3" 8.75 3393 - 562239 - - - 1.4265 - 1.409 0.208 - 144.8 1 2 0 0.0012 8 0 0 0 2.47E+07 1.44E+07 - - - 1.611 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.16947.16947.2 0.00104 16-Aug R.WGEPEPFLR.L "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 5 1129.5556 2.87 31496 16947 2 1129.555631 565.7851 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.53 3393.6 - 360481 - - - -0.0115 - 1.572 0.369 - 196.2 1 2 0 0 9 0 0 0 1.22E+07 4.24E+06 - - - 3.0751 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.16952.16952.2 0.00097 16-Aug R.ELLTEFGYK.G sp|P49411|EFTU_HUMAN 1 1098.5597 2.89 31499 16952 2 1098.563267 550.2871 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.53 3394.2 - 2.00E+06 - - - 3.2224 - 1.634 0.482 - 231.3 1 2 0 0.0035 9 0 0 0 4.41E+07 1.53E+07 - - - 4.0205 0.9607 230117_WJC_METTL3_WT_vs_EV_F04.16953.16953.2 0.0106 22-Jun R.IINEPTAAAIAY.G "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 16 1245.6605 - 31500 16953 2 1245.662697 623.8375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4 3394.2 - 1.63E+06 - - - 1.7605 - 1.579 0.406 - 86 1 1 0 0.0022 12 0 0 0 - - - - - 3.2409 1 230117_WJC_METTL3_WT_vs_EV_F04.16955.16955.2 6.54E-06 13/18 K.VTDAIVLLDR.E "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1113.6394 2.7 31502 16955 2 1113.642114 557.827 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.21 3394.5 - 600582 - - - 2.4604 - 2.705 0.475 - 492.1 1 2 0 0.0027 10 0 0 0 1.49E+08 5.52E+07 - - - 5.3261 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.16956.16956.2 5.35E-06 16-Sep R.ELLTEFGYK[136.11].G sp|P49411|EFTU_HUMAN 1 1106.5739 2.9 31503 16956 2 1106.578114 554.2942 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.53 3394.6 - 467914 - - - 3.7838 - 1.889 0.487 - 222.7 1 2 0 0.0042 9 0 0 0 4.43E+07 1.53E+07 - - - 4.4768 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.16959.16959.2 0.0531 20-Aug K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 4.24 31505 16959 2 1235.762899 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3395 - 683043 - - - 2.2181 - 1.849 0.328 - 190.4 1 2 0 0.0027 11 0 0 0 2.21E+07 5.21E+06 - - - 3.1255 0.9948 230117_WJC_METTL3_WT_vs_EV_F04.16963.16963.2 0.0629 12-Jul R.VPFSLLR[166.11].G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 840.5097 0.97 31508 16963 2 840.510545 421.2621 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3395.3 - 1.41E+06 - - - 1.0125 - 1.241 0.168 - 212.1 1 2 0 0.0009 7 0 0 0 6.99E+07 7.18E+07 - - - 0.9657 0.998 230117_WJC_METTL3_WT_vs_EV_F04.16964.16964.2 0.0146 12-Jul R.VPFSLLR.G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 830.5014 1.03 31509 16964 2 830.502276 416.258 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3395.4 - 1.28E+06 - - - 1.0259 - 1.333 0.239 - 204.9 1 2 0 0.0009 7 0 0 0 6.93E+07 6.73E+07 - - - 1.7167 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.16966.16966.2 0.000154 18-Dec K.VTDAIVLLDR[166.11].E "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1123.6476 2.7 31511 16966 2 1123.64971 562.8311 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.21 3395.6 - 536783 - - - 1.8387 - 2.422 0.401 - 484.2 1 2 0 0.0021 10 0 0 0 1.49E+08 5.52E+07 - - - 4.4713 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.16967.16967.2 5.15E-05 22-Sep K.VLQGDLVMNVYR.D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1405.7388 2.48 31512 16967 2 1405.744869 703.8767 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3395.8 - 322716 - - - 4.3379 - 2.01 0.46 - 302.9 1 2 0 0.0061 12 0 0 0 2.78E+06 1.12E+06 - - - 4.2736 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.16971.16971.2 0.116 14-Jul K.AGPIWDLR[166.11].L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 936.5057 0.95 31514 16971 2 936.507736 469.2601 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3396.3 - 3.04E+06 - - - 2.205 - 1.418 0.255 - 239.8 1 2 0 0.0021 8 0 0 0 4.20E+08 4.44E+08 - - - 1.9771 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.16972.16972.2 0.000139 14-Aug K.AGPIWDLR.L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 926.4974 0.95 31515 16972 2 926.499038 464.256 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3396.4 - 2.33E+06 - - - 1.7669 - 1.586 0.314 - 286.6 1 2 0 0.0016 8 0 0 0 4.20E+08 4.44E+08 - - - 2.7507 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.16976.16976.2 0.000193 20-Sep R.IDGLAALSMDR[166.11].T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1170.5942 1.89 31519 16976 2 1170.595883 586.3044 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3396.8 - 352706 - - - 1.4138 - 1.89 0.453 - 165 1 2 0 0.0017 11 0 0 0 1.46E+07 7.71E+06 - - - 4.1084 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.16983.16983.2 0.000708 14-Sep K.MFGMVLEK.L sp|P55060|XPO2_HUMAN 1 953.4714 2.34 31524 16983 2 953.4736 477.743 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.75 3397.6 - 1.73E+06 - - - 2.2591 - 1.418 0.457 - 230.3 1 2 0 0.0022 8 0 0 0 6.74E+07 2.88E+07 - - - 3.469 0.9598 230117_WJC_METTL3_WT_vs_EV_F04.16990.16990.2 0.386 12-Jun K.SYSLLFR[166.11].V "sp|Q15022|SUZ12_HUMAN,tr|J3QQW9|J3QQW9_HUMAN" 2 894.4839 0.78 31529 16990 2 894.487772 448.2492 Polycomb protein SUZ12 OS=Homo sapiens OX=9606 GN=SUZ12 PE=1 SV=3 8.46 3398.5 - 273693 - - - 4.3589 - 1.257 0.122 - 78 2 2 0 0.0039 7 0 0 0 1.21E+07 1.55E+07 - - - 0.5311 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.16998.16998.2 8.63E-06 20-Oct R.IDGLAALSMDR.T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1160.586 1.64 31535 16998 2 1160.587397 581.3003 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3399.4 - 976250 - - - 1.2399 - 2.269 0.411 - 279.1 1 2 0 0.0014 11 0 0 0 1.56E+07 9.56E+06 - - - 4.2927 0.9877 230117_WJC_METTL3_WT_vs_EV_F04.17011.17011.2 0.00046 22-Nov R.AAVLFATDIAAR[166.11].G "sp|Q13206|DDX10_HUMAN,tr|A0A3B3ISR7|A0A3B3ISR7_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 3 1227.6851 1.08 31545 17011 2 1227.694134 614.8498 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 5.88 3401.1 - 237610 - - - 7.3651 - 2.081 0.358 - 246.2 1 2 0 0.009 12 0 0 0 5.05E+06 4.69E+06 - - - 3.6106 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.17015.17015.2 0.000155 12-Jul R.YGDFFIR.Q "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|H0Y7E6|H0Y7E6_HUMAN,tr|B0QY90|B0QY90_HUMAN" 4 916.4443 0.61 31547 17015 2 916.445713 459.2294 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 5.84 3401.6 - 4.43E+06 - - - 1.5386 - 1.571 0.478 - 141.1 1 2 0 0.0014 7 0 0 0 4.57E+07 7.54E+07 - - - 4.0023 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.17016.17016.2 0.0254 12-Aug R.DGFGFIK.C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 782.3963 1.83 31548 17016 2 782.397043 392.2054 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3401.7 - 3.26E+06 - - - 0.9624 - 1.273 0.232 - 241.6 1 2 0 0.0008 7 0 0 0 6.26E+07 3.43E+07 - - - 1.5191 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17017.17017.2 0.00515 14-Sep K.VDLVLLGK.Q sp|P38117|ETFB_HUMAN 1 855.543 1.8 31549 17017 2 855.545221 428.7788 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3401.8 - 8.08E+06 - - - 2.6498 - 2.008 0.451 - 307.2 1 2 0 0.0023 8 0 0 0 9.67E+07 5.36E+07 - - - 4.4739 0.992 230117_WJC_METTL3_WT_vs_EV_F04.17023.17023.2 0.699 14-Aug K.IMLAIITK.M "sp|P78412|IRX6_HUMAN,sp|P78414|IRX1_HUMAN,sp|P78413|IRX4_HUMAN,sp|Q9BZI1|IRX2_HUMAN,sp|P78411|IRX5_HUMAN,sp|P78415|IRX3_HUMAN,tr|D6RAS8|D6RAS8_HUMAN" 7 901.5671 0.66 31553 17023 2 901.568355 451.7908 Iroquois-class homeodomain protein IRX-6 OS=Homo sapiens OX=9606 GN=IRX6 PE=1 SV=3 8.75 3402.5 - 452553 - - - 1.4353 - 1.197 0.142 - 116.3 1 2 0 0.0013 8 0 0 0 9.09E+06 1.39E+07 - - - 0.6317 0.9659 230117_WJC_METTL3_WT_vs_EV_F04.17024.17024.2 0.0109 14-Sep K.PFYPALIR[166.11].Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 985.5625 0.76 31554 17024 2 985.563532 493.7885 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.18 3402.6 - 2.13E+06 - - - 1.0897 - 1.796 0.353 - 366.9 1 1 0 0.0011 8 0 0 0 6.10E+07 7.98E+07 - - - 3.4139 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.17025.17025.2 0.0878 12-Jul R.DGFGFIK[136.11].C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 790.4105 1.99 31555 17025 2 790.411312 396.2125 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3402.6 - 772295 - - - 1.04 - 1.305 0.279 - 185.8 1 2 0 0.0008 7 0 0 0 6.22E+07 3.13E+07 - - - 1.9449 0.985 230117_WJC_METTL3_WT_vs_EV_F04.17026.17026.2 0.263 14-Aug R.LDNIFLTR.M "sp|Q9BQ52|RNZ2_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|V9GYS7|V9GYS7_HUMAN,tr|J3QLK4|J3QLK4_HUMAN,tr|V9GYU5|V9GYU5_HUMAN,tr|V9GZ72|V9GZ72_HUMAN,tr|J3QL08|J3QL08_HUMAN,tr|J3QRS2|J3QRS2_HUMAN" 8 990.5498 0.2 31556 17026 2 990.545921 496.2822 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 5.84 3402.7 - 1.98E+06 - - - -3.9473 - 1.59 0.284 - 167.7 1 2 0 -0.0039 8 0 0 0 3.33E+07 1.70E+08 - - - 2.536 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17031.17031.2 0.0278 16-Nov R.FAVGIVIGR.N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 930.5651 1.44 31559 17031 2 930.567663 466.2898 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3403.2 - 5.53E+06 - - - 2.7682 - 1.954 0.394 - 515.2 1 2 0 0.0026 9 0 0 0 2.36E+08 1.65E+08 - - - 3.8883 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17038.17038.2 0.000138 18-Sep R.FFNYVPSGIR[166.11].C "sp|Q969X6|UTP4_HUMAN,tr|H3BPD7|H3BPD7_HUMAN" 2 1208.6218 1.44 31564 17038 2 1208.624834 605.3182 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 8.75 3404 - 751335 - - - 2.5401 - 1.673 0.412 - 214.5 1 2 0 0.0031 10 0 0 0 1.90E+07 1.32E+07 - - - 3.5195 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17039.17039.2 0.00148 16-Oct R.FAVGIVIGR[166.11].N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 940.5734 1.47 31565 17039 2 940.574948 471.294 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3404 - 6.38E+06 - - - 1.6915 - 1.9 0.371 - 380.9 1 2 0 0.0016 9 0 0 0 2.45E+08 1.66E+08 - - - 3.6376 0.9605 230117_WJC_METTL3_WT_vs_EV_F04.17043.17043.2 0.00165 16-Aug F.VLVLYDEIK.K "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 3 1090.6274 0.21 31567 17043 2 1090.629571 546.321 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 4.37 3404.5 - 168603 - - - 1.9796 - 1.73 0.364 - 153.2 1 1 0 0.0022 9 0 0 0 1.72E+07 8.32E+07 - - - 3.3146 0.9583 230117_WJC_METTL3_WT_vs_EV_F04.17046.17046.2 3.85 12-Jun K.MVLIALR.K sp|O94822|LTN1_HUMAN 1 814.5099 1.71 31569 17046 2 814.510338 408.2622 E3 ubiquitin-protein ligase listerin OS=Homo sapiens OX=9606 GN=LTN1 PE=1 SV=6 9.5 3404.8 - 107112 - - - 0.5623 - 0.992 0.08 - 78.6 1 2 0 0.0005 7 0 0 0 5.45E+06 3.18E+06 - - - -0.3937 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.17050.17050.2 0.059 14-Sep R.ITVLEALR.H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 913.5597 1.31 31571 17050 2 913.56172 457.7871 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3405.4 - 2.53E+06 - - - 2.2473 - 1.986 0.25 - 290.7 1 2 0 0.0021 8 0 0 0 1.43E+08 1.09E+08 - - - 2.9562 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.17051.17051.2 0.141 13/16 K.RVLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1037.7073 1.27 31572 17051 2 1037.711442 519.8609 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3405.5 - 964571 - - - 3.9587 - 2.046 0.288 - 326.7 1 2 0 0.0041 9 0 0 0 2.12E+08 1.67E+08 - - - 3.238 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.17052.17052.2 0.000207 20-Dec K.ALADVATVLGR.A "sp|Q92542|NICA_HUMAN,tr|H0Y6T7|H0Y6T7_HUMAN" 2 1084.6241 3.69 31573 17052 2 1084.624714 543.3193 Nicastrin OS=Homo sapiens OX=9606 GN=NCSTN PE=1 SV=2 5.88 3405.6 - 820144 - - - 0.6048 - 2.163 0.227 - 361.9 1 2 0 0.0007 11 0 0 0 8.53E+06 2.31E+06 - - - 2.8045 0.9924 230117_WJC_METTL3_WT_vs_EV_F04.17055.17055.2 0.474 18-Jun R.IFLPPPPGIR.K "sp|Q8IX18|DHX40_HUMAN,tr|F5H625|F5H625_HUMAN" 2 1105.6648 1.73 31576 17055 2 1105.667483 553.8397 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 9.75 3406 - 225548 - - - 2.4257 - 1.359 0.132 - 79.9 1 2 0 0.0027 10 0 0 0 1.31E+07 7.56E+06 - - - 0.8713 0.9948 230117_WJC_METTL3_WT_vs_EV_F04.17060.17060.2 0.319 16-Jul K.ILAPYLEMK.D "sp|Q96FV9|THOC1_HUMAN,tr|A0A087WWS1|A0A087WWS1_HUMAN" 2 1076.594 2 31580 17060 2 1076.594492 539.3043 THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1 6 3406.6 - 92181.9 - - - 0.4533 - 1.152 0.221 - 112.7 1 2 0 0.0005 9 0 0 0 1.06E+07 5.27E+06 - - - 1.0825 0.8934 230117_WJC_METTL3_WT_vs_EV_F04.17064.17064.2 0.0328 18-Oct M.IAGGLFVMDK.F sp|Q10471|GALT2_HUMAN 1 1049.558 0.79 31584 17064 2 1049.56037 525.7863 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.84 3406.9 - 582502 - - - 2.3029 - 2.085 0.15 - 191.5 1 1 0 0.0024 10 0 0 0 1.76E+07 2.23E+07 - - - 2.1991 0.9732 230117_WJC_METTL3_WT_vs_EV_F04.17068.17068.2 0.923 12-Jul K.YGLLFER[166.11].S sp|Q9H1A4|APC1_HUMAN 1 906.4839 1.22 31588 17068 2 906.486028 454.2492 Anaphase-promoting complex subunit 1 OS=Homo sapiens OX=9606 GN=ANAPC1 PE=1 SV=1 6 3407.4 - 193524 - - - 2.3773 - 1.077 0.095 - 105 1 2 0 0.0022 7 0 0 0 9.71E+06 7.98E+06 - - - -0.023 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.17072.17072.2 0.328 16-Nov K.R[166.11]VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1057.7239 1.27 31590 17072 2 1057.726746 529.8692 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3407.9 - 1.99E+06 - - - 2.7153 - 2.009 0.264 - 207.1 1 2 0 0.0029 9 0 0 0 2.13E+08 1.67E+08 - - - 3.0083 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17073.17073.2 0.000563 18-Dec R.LLDYVPIGPR.F "sp|P46459|NSF_HUMAN,tr|K7EQD6|K7EQD6_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 4 1141.6495 1.52 31591 17073 2 1141.653092 571.832 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.84 3408 - 596373 - - - 3.1069 - 2.173 0.409 - 450.3 1 2 0 0.0035 10 0 0 0 4.04E+07 2.65E+07 - - - 4.2271 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17074.17074.2 0.00391 14-Aug R.ITVLEALR[166.11].H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 923.5679 1.31 31592 17074 2 923.569761 462.7912 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3408.1 - 4.23E+06 - - - 1.9749 - 1.817 0.354 - 247 1 2 0 0.0018 8 0 0 0 1.43E+08 1.09E+08 - - - 3.4562 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.17075.17075.2 0.0771 14-Aug R.IAYFTLPK.T sp|Q92900|RENT1_HUMAN 1 951.543 0.81 31593 17075 2 951.546054 476.7788 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.59 3408.1 - 1.70E+06 - - - 3.2579 - 1.669 0.323 - 187.6 1 2 0 0.0031 8 0 0 0 6.84E+07 8.45E+07 - - - 2.9706 0.9796 230117_WJC_METTL3_WT_vs_EV_F04.17078.17078.2 0.0498 18-Oct R.LLDYVPIGPR[166.11].F "sp|P46459|NSF_HUMAN,tr|K7EQD6|K7EQD6_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 4 1151.6578 1.52 31596 17078 2 1151.668145 576.8362 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.84 3408.4 - 456576 - - - 8.9697 - 2.08 0.35 - 277.5 1 2 0 0.0103 10 0 0 0 4.04E+07 2.65E+07 - - - 3.6671 0.9947 230117_WJC_METTL3_WT_vs_EV_F04.17079.17079.2 0.273 14-Sep R.LLLAALGR[166.11].R "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 835.5519 1.27 31597 17079 2 835.552136 418.7832 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 9.75 3408.6 - 292869 - - - 0.2908 - 1.698 0.065 - 226.4 1 2 0 0.0002 8 0 0 0 5.43E+07 4.27E+07 - - - 1.1178 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.17083.17083.2 0.379 16-Jul R.GLVGEIIK[136.11]R[166.11].F "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1001.6352 1.96 31599 17083 2 1001.636415 501.8249 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3409.1 - 1.02E+07 - - - 1.1781 - 1.407 0.162 - 147.7 1 2 0 0.0012 9 0 0 0 2.46E+08 1.25E+08 - - - 1.225 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.17084.17084.2 0.287 14-Sep K.AGISFIIK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 847.5167 0.86 31600 17084 2 847.517309 424.7656 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.8 3409.2 - 2.54E+06 - - - 0.6714 - 1.528 0.159 - 216.8 1 2 0 0.0006 8 0 0 0 1.79E+09 2.07E+09 - - - 1.4938 0.9965 230117_WJC_METTL3_WT_vs_EV_F04.17086.17086.2 1.68 14-Jul R.EILETLIK[136.11].G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 965.5888 1.67 31602 17086 2 965.5904 483.8017 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3409.3 - 927281 - - - 1.6063 - 1.343 0.181 - 138.1 1 2 0 0.0016 8 0 0 0 1.75E+08 1.05E+08 - - - 1.2668 0.9456 230117_WJC_METTL3_WT_vs_EV_F04.17088.17088.2 0.0559 14-Aug C.LNLWGYER.V sp|Q86U44|MTA70_HUMAN 1 1049.5294 0.65 31604 17088 2 1049.531095 525.772 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3409.5 - 558168 - - - 1.5864 - 2.018 0.217 - 219.9 1 1 0 0.0017 8 0 0 0 1.59E+07 2.46E+07 - - - 2.7608 0.982 230117_WJC_METTL3_WT_vs_EV_F04.17095.17095.2 2.12 14-Jul R.EILETLIK.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 957.5746 1.67 31609 17095 2 957.578435 479.7946 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3410.5 - 1.38E+06 - - - 3.9537 - 1.389 0.121 - 153.4 1 2 0 0.0038 8 0 0 0 1.76E+08 1.06E+08 - - - 0.9245 0.9659 230117_WJC_METTL3_WT_vs_EV_F04.17096.17096.2 0.000148 16-Oct F.ADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 952.5957 14 31610 17096 2 952.598491 477.3051 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3410.5 - 1.41E+06 - - - 2.911 - 1.942 0.485 - 279.1 1 1 0 0.0028 9 0 0 0 4.01E+07 2.86E+06 - - - 4.5425 0.9766 230117_WJC_METTL3_WT_vs_EV_F04.17098.17098.2 0.492 12-Jun K.LYIEFVK[136.11].G "sp|Q14165|MLEC_HUMAN,tr|H0YG07|H0YG07_HUMAN,tr|F5H1S8|F5H1S8_HUMAN" 3 918.5306 1.66 31612 17098 2 918.530173 460.2726 Malectin OS=Homo sapiens OX=9606 GN=MLEC PE=1 SV=1 6 3410.8 - 405250 - - - -0.4703 - 1.275 0.071 - 93.3 1 2 0 -0.0004 7 0 0 0 1.48E+07 8.93E+06 - - - 0.3351 0.9955 230117_WJC_METTL3_WT_vs_EV_F04.17099.17099.2 0.0525 12-Jun K.ISFELMR.E "sp|Q9UNE7|CHIP_HUMAN,tr|H3BUD0|H3BUD0_HUMAN,tr|H3BTA3|H3BTA3_HUMAN" 3 894.4633 5 31613 17099 2 894.462887 448.2389 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 6 3410.9 - 398316 - - - -0.4886 - 1.372 0.21 - 84.5 1 2 0 -0.0004 7 0 0 0 2.84E+07 5.67E+06 - - - 1.594 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17104.17104.2 0.000116 14-Nov K.LMNLWTER.F "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1061.5328 0.34 31616 17104 2 1061.536142 531.7737 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 3411.5 - 2.56E+06 - - - 3.1473 - 1.867 0.423 - 526.8 1 2 0 0.0033 8 0 0 0 2.23E+08 6.48E+08 - - - 4.0472 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.17105.17105.2 0.00208 18-Oct R.LGGIGQFLAK[136.11].A sp|Q08211|DHX9_HUMAN 1 1010.6004 0.82 31617 17105 2 1010.603384 506.3075 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3411.6 - 1.58E+06 - - - 2.9369 - 2.208 0.228 - 214 1 2 0 0.003 10 0 0 0 2.93E+08 3.56E+08 - - - 2.935 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17113.17113.2 0.0756 16-Sep R.VLIFSQMTR.V "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 1093.5954 0.9 31623 17113 2 1093.597016 547.805 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 9.72 3412.4 - 806781 - - - 1.4768 - 1.808 0.32 - 240.8 1 2 0 0.0016 9 0 0 0 1.94E+07 2.15E+07 - - - 3.1173 0.997 230117_WJC_METTL3_WT_vs_EV_F04.17117.17117.2 0.00588 16-Oct K.LNNLVLFDK[136.11].A sp|P62851|RS25_HUMAN 1 1082.6215 1.02 31625 17117 2 1082.618547 542.318 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3412.9 - 300714 - - - -2.7701 - 2.278 0.319 - 256.5 1 2 0 -0.003 9 0 0 0 6.69E+08 6.57E+08 - - - 3.778 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.17118.17118.2 0.00196 26-Nov R.LGGIPVGVVAVETR.T "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 1365.798 1.85 31626 17118 2 1365.798316 683.9063 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 6 3413.1 - 148424 - - - 0.2314 - 2.038 0.494 - 323.7 1 2 0 0.0003 14 0 0 0 4.51E+06 2.44E+06 - - - 4.4762 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.17119.17119.2 0.016 14-Jul K.AVPSWFVR[166.11].V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 970.5264 2.31 31627 17119 2 970.527014 486.2705 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3413.1 - 1.76E+06 - - - 0.6254 - 1.4 0.244 - 196.8 1 2 0 0.0006 8 0 0 0 1.15E+08 4.98E+07 - - - 1.8578 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17120.17120.2 0.00281 16-Sep R.AGFVPVYLR[166.11].Q "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1030.5839 0.7 31628 17120 2 1030.585506 516.2992 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 8.79 3413.2 - 1.54E+06 - - - 1.537 - 1.641 0.432 - 254.4 1 2 0 0.0016 9 0 0 0 4.27E+07 6.12E+07 - - - 3.6642 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.17122.17122.2 0.0228 22-Oct -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 1.33 31630 17122 2 1306.771806 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3413.5 - 284877 - - - 2.6983 - 1.639 0.272 - 206.4 1 2 0 0.0035 12 0 0 0 5.59E+06 4.21E+06 - - - 2.3489 0.914 230117_WJC_METTL3_WT_vs_EV_F04.17123.17123.2 0.0165 20-Aug R.QLYHLGVVEAY.S sp|Q08211|DHX9_HUMAN 1 1290.6608 - 31631 17123 2 1290.66419 646.3377 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.24 3413.6 - 273223 - - - 2.5971 - 1.434 0.351 - 140 1 1 0 0.0034 11 0 0 0 - - - - - 2.6076 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17127.17127.2 7.39E-05 18-Oct R.LGGIGQFLAK.A sp|Q08211|DHX9_HUMAN 1 1002.5862 0.82 31633 17127 2 1002.588856 502.3004 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3414.1 - 5.18E+06 - - - 2.6332 - 2.14 0.327 - 227.1 1 2 0 0.0026 10 0 0 0 2.93E+08 3.58E+08 - - - 3.579 0.9957 230117_WJC_METTL3_WT_vs_EV_F04.17128.17128.2 3.05 14-Aug R.LLLAALGR.R "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 825.5436 1.26 31634 17128 2 825.544012 413.7791 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 9.75 3414.2 - 6.42E+06 - - - 0.4712 - 1.553 0.116 - 166.8 1 2 0 0.0004 8 0 0 0 5.38E+07 4.26E+07 - - - 1.2252 0.9942 230117_WJC_METTL3_WT_vs_EV_F04.17129.17129.2 0.38 14-Aug K.TLVLLMGK.E "sp|P07737|PROF1_HUMAN,tr|K7EJ44|K7EJ44_HUMAN" 2 873.5358 0.85 31635 17129 2 873.535574 437.7752 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 8.41 3414.2 - 1.81E+06 - - - -0.2141 - 1.333 0.181 - 221.6 1 2 0 -0.0002 8 0 0 0 4.27E+07 5.05E+07 - - - 1.2447 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.17131.17131.2 0.00641 18-Oct K.VALDLDPYVK[136.11].K sp|O95295|SNAPN_HUMAN 1 1139.6318 2.25 31637 17131 2 1139.633292 570.8232 SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN PE=1 SV=1 4.21 3414.4 - 1.78E+06 - - - 1.3303 - 1.747 0.462 - 238.1 1 2 0 0.0015 10 0 0 0 2.78E+07 1.23E+07 - - - 4.0101 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.17135.17135.2 3.76E-06 20-Nov R.IENVVLVVPVK.T "sp|Q9NQW7|XPP1_HUMAN,tr|Q5T6H7|Q5T6H7_HUMAN" 2 1207.754 4.32 31641 17135 2 1207.75142 604.8843 Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3 6 3414.9 - 543200 - - - -2.1445 - 2.033 0.448 - 265.6 1 2 0 -0.0026 11 0 0 0 3.63E+06 8.42E+05 - - - 4.2685 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17143.17143.2 0.000145 18-Nov K.VALDLDPYVK.K sp|O95295|SNAPN_HUMAN 1 1131.6176 2.25 31647 17143 2 1131.61794 566.8161 SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN PE=1 SV=1 4.21 3415.8 - 3.43E+06 - - - 0.3217 - 2.176 0.402 - 413.6 1 2 0 0.0004 10 0 0 0 2.78E+07 1.23E+07 - - - 4.1803 0.9847 230117_WJC_METTL3_WT_vs_EV_F04.17145.17145.2 0.00287 20-Oct R.LYPVLQQSLVR.A sp|Q5RKV6|EXOS6_HUMAN 1 1314.766 0.75 31649 17145 2 1314.774563 658.3903 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.75 3416.1 - 1.20E+06 - - - 6.5342 - 1.612 0.313 - 313.8 1 2 0 0.0086 11 0 0 0 8.20E+06 1.09E+07 - - - 2.6418 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.17152.17152.2 0.171 14-Jun R.VIPLPQWK.A sp|Q96ES7|SGF29_HUMAN 1 979.5855 1.82 31654 17152 2 979.586933 490.8 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 8.72 3417 - 1.79E+06 - - - 1.4751 - 1.267 0.275 - 120 1 2 0 0.0014 8 0 0 0 2.42E+07 1.33E+07 - - - 1.7854 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.17154.17154.2 0.00807 14-Aug R.TFLVPEIK.S sp|Q9P1Y5|CAMP3_HUMAN 1 945.5535 0.89 31656 17154 2 945.554204 473.784 Calmodulin-regulated spectrin-associated protein 3 OS=Homo sapiens OX=9606 GN=CAMSAP3 PE=1 SV=2 5.66 3417.2 - 872765 - - - 0.7244 - 1.285 0.296 - 184 1 2 0 0.0007 8 0 0 0 9.65E+06 1.08E+07 - - - 1.9833 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.17160.17160.2 0.0205 16-Oct K.LNNLVLFDK.A sp|P62851|RS25_HUMAN 1 1074.6073 1.02 31660 17160 2 1074.607831 538.3109 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3418 - 1.37E+07 - - - 0.4513 - 2.363 0.369 - 344.7 1 2 0 0.0005 9 0 0 0 6.71E+08 6.59E+08 - - - 4.2541 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.17162.17162.2 0.00802 14-Jun K.AVPSWFVR.V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 960.5181 1.72 31662 17162 2 960.518863 481.2663 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3418.1 - 2.77E+06 - - - 0.7558 - 1.272 0.339 - 119.4 1 2 0 0.0007 8 0 0 0 8.08E+07 4.71E+07 - - - 2.2702 0.9939 230117_WJC_METTL3_WT_vs_EV_F04.17165.17165.2 1.1 12-Jul K.GLLDDLR.N sp|Q07065|CKAP4_HUMAN 1 800.4392 1.4 31665 17165 2 800.440318 401.2269 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.21 3418.5 - 304993 - - - 1.3742 - 1.263 0.141 - 193.1 1 2 0 0.0011 7 0 0 0 2.94E+07 2.10E+07 - - - 0.8219 0.991 230117_WJC_METTL3_WT_vs_EV_F04.17176.17176.2 0.222 12-Jun K.YLELFQR[166.11].Q "sp|Q9UBQ6|EXTL2_HUMAN,tr|C9JEG3|C9JEG3_HUMAN" 2 977.521 0.97 31674 17176 2 977.520486 489.7678 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 6 3419.9 - 881222 - - - -0.5125 - 1.348 0.144 - 146.4 1 2 0 -0.0005 7 0 0 0 6.82E+06 7.00E+06 - - - 1.0506 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.17177.17177.2 0.0227 14-Jun K.LFIGMISK.K "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 907.5201 1.42 31675 17177 2 907.520449 454.7673 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.75 3420 - 1.35E+06 - - - 0.3724 - 1.337 0.393 - 80.7 1 2 0 0.0003 8 0 0 0 7.89E+06 5.55E+06 - - - 2.8195 0.9628 230117_WJC_METTL3_WT_vs_EV_F04.17178.17178.2 12 12-Aug K.LPLISLR.L "sp|Q96RL7|VP13A_HUMAN,sp|Q6UXB3|LYPD2_HUMAN,sp|Q6DN12|MCTP2_HUMAN,tr|I6L8E2|I6L8E2_HUMAN" 4 810.5327 1.51 31676 17178 2 810.532908 406.2736 Vacuolar protein sorting-associated protein 13A OS=Homo sapiens OX=9606 GN=VPS13A PE=1 SV=2 9.75 3420.1 - 1.33E+06 - - - 0.227 - 1.122 0.049 - 160.7 1 2 0 0.0002 7 0 0 0 1.01E+07 6.68E+06 - - - -0.2324 0.96 230117_WJC_METTL3_WT_vs_EV_F04.17184.17184.2 0.00207 22-Aug R.VINEPTAAALAY.G "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1231.6449 - 31680 17184 2 1231.646075 616.8297 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4 3420.8 - 737892 - - - 0.9922 - 1.52 0.413 - 128.1 1 1 0 0.0012 12 0 0 0 - - - - - 3.1927 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.17185.17185.2 2.50E-05 14-Aug K.MVGFIIGR.G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 891.5 1.45 31681 17185 2 891.50084 446.7573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3420.9 - 1.42E+06 - - - 0.8929 - 1.653 0.528 - 186.4 1 2 0 0.0008 8 0 0 0 3.72E+08 2.56E+08 - - - 4.4564 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.17186.17186.2 0.0413 16-Aug R.FGIWTGEYK[136.11].C sp|Q9NUD5|ZCHC3_HUMAN 1 1107.548 1.81 31682 17186 2 1107.551597 554.7813 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 6 3420.9 - 530320 - - - 3.2062 - 1.572 0.219 - 113.7 1 2 0 0.0036 9 0 0 0 1.26E+07 6.95E+06 - - - 1.9661 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.17187.17187.2 0.000176 22-Sep R.IVPGQFLAVDPK.G sp|Q15393|SF3B3_HUMAN 1 1282.7285 1.35 31683 17187 2 1282.732602 642.3715 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3421.1 - 159085 - - - 3.1792 - 1.718 0.399 - 190.6 1 2 0 0.0041 12 0 0 0 2.35E+07 1.74E+07 - - - 3.4106 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17189.17189.2 0.000314 22-Aug R.ILYIVASDPYSR.L "sp|Q9ULT8|HECD1_HUMAN,tr|H0YJD4|H0YJD4_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN,tr|H0YJP0|H0YJP0_HUMAN" 4 1395.7398 5.63 31685 17189 2 1395.743374 698.8772 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 5.83 3421.3 - 107213 - - - 2.5485 - 1.891 0.442 - 239.2 1 2 0 0.0036 12 0 0 0 2.49E+06 4.41E+05 - - - 3.9808 0.9948 230117_WJC_METTL3_WT_vs_EV_F04.17191.17191.2 0.0374 24-Sep K.LLPHQLYGVVPQA.- "sp|P18887|XRCC1_HUMAN,tr|F5H8D7|F5H8D7_HUMAN" 2 1433.8031 - 31687 17191 2 1433.800416 717.9088 DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2 6.74 3421.6 - 0 - - - -1.8615 - 1.669 0.26 - 171.7 1 2 0 -0.0027 13 0 0 0 - - - - - 2.2752 0.9846 230117_WJC_METTL3_WT_vs_EV_F04.17194.17194.2 0.715 12-Jun K.GLLDDLR[166.11].N sp|Q07065|CKAP4_HUMAN 1 810.4475 1.39 31689 17194 2 810.447663 406.231 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.21 3421.9 - 874828 - - - 0.2159 - 1.158 0.116 - 134.3 1 2 0 0.0002 7 0 0 0 2.92E+07 2.10E+07 - - - 0.3625 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17197.17197.2 0.00332 14-Aug K.LFDFVNAK.K "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 952.5018 0.43 31691 17197 2 952.504487 477.2582 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 5.84 3422.2 - 1.32E+06 - - - 2.8021 - 1.596 0.461 - 160.1 1 2 0 0.0027 8 0 0 0 3.87E+07 9.06E+07 - - - 3.8551 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17199.17199.2 0.000396 22-Aug R.IVPGQFLAVDPK[136.11].G sp|Q15393|SF3B3_HUMAN 1 1290.7427 1.35 31693 17199 2 1290.74548 646.3786 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3422.5 - 316091 - - - 2.1352 - 1.793 0.464 - 95.9 1 2 0 0.0028 12 0 0 0 2.35E+07 1.74E+07 - - - 4.0036 0.9961 230117_WJC_METTL3_WT_vs_EV_F04.17200.17200.2 0.000199 20-Oct R.LYPVLQQSLVR[166.11].A sp|Q5RKV6|EXOS6_HUMAN 1 1324.7742 0.75 31694 17200 2 1324.781577 663.3944 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.75 3422.6 - 223780 - - - 5.5368 - 1.746 0.418 - 239 1 2 0 0.0073 11 0 0 0 7.88E+06 1.05E+07 - - - 3.6337 0.9933 230117_WJC_METTL3_WT_vs_EV_F04.17208.17208.2 0.541 12-Jul R.GFLYFNR[166.11].Q sp|Q10570|CPSF1_HUMAN 1 925.4686 1.74 31700 17208 2 925.469064 463.7416 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3423.7 - 899185 - - - 0.5478 - 1.224 0.16 - 175.1 1 2 0 0.0005 7 0 0 0 9.18E+06 5.26E+06 - - - 0.863 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.17214.17214.2 0.122 20-Sep K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.85 31706 17214 2 1245.771177 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3424.3 - 505369 - - - 2.2067 - 1.794 0.302 - 208.8 1 2 0 0.0027 11 0 0 0 2.01E+07 1.09E+07 - - - 2.8518 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.17217.17217.2 0.128 16-Aug R.TFTNVYWMK[136.11].V sp|Q9HBH1|DEFM_HUMAN 1 1196.578 1.11 31709 17217 2 1196.581516 599.2963 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 8.26 3424.7 - 174526 - - - 2.9668 - 1.223 0.341 - 142.2 1 2 0 0.0035 9 0 0 0 6.03E+06 5.41E+06 - - - 2.1409 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.17221.17221.2 0.0341 20-Jun K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.18 31712 17221 2 1235.764269 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3425.2 - 302470 - - - 3.3267 - 1.677 0.389 - 105.6 1 2 0 0.0041 11 0 0 0 8.39E+06 7.11E+06 - - - 3.3115 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.17222.17222.2 0.0223 18-Aug R.LINLVGESLR.L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1112.6554 4.38 31713 17222 2 1112.656871 557.335 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6 3425.3 - 292723 - - - 1.3589 - 1.705 0.312 - 129.5 1 2 0 0.0015 10 0 0 0 1.47E+08 3.35E+07 - - - 2.8343 0.9688 230117_WJC_METTL3_WT_vs_EV_F04.17223.17223.2 0.0222 16-Sep D.IPIILVGNK.S "sp|P55040|GEM_HUMAN,sp|Q8IXI2|MIRO1_HUMAN,tr|H7BXZ6|H7BXZ6_HUMAN" 3 965.6274 2.33 31714 17223 2 965.629147 483.821 GTP-binding protein GEM OS=Homo sapiens OX=9606 GN=GEM PE=1 SV=1 8.75 3425.4 - 607818 - - - 1.8579 - 1.91 0.371 - 216.7 1 1 0 0.0018 9 0 0 0 5.58E+06 2.40E+06 - - - 3.6527 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17225.17225.2 0.00729 24-Oct K.LLLGAGAVAYGVR.E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1258.7398 1.33 31716 17225 2 1258.741485 630.3772 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3425.7 - 513582 - - - 1.3728 - 2.012 0.338 - 230.4 1 2 0 0.0017 13 0 0 0 1.48E+08 1.11E+08 - - - 3.3313 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17226.17226.2 0.0461 18-Aug -.MLIEDVDALK.S "sp|Q9P2N5|RBM27_HUMAN,tr|U3KPZ7|U3KPZ7_HUMAN" 2 1145.6002 0.62 31717 17226 2 1145.601765 573.8074 RNA-binding protein 27 OS=Homo sapiens OX=9606 GN=RBM27 PE=1 SV=2 4.03 3425.8 - 498232 - - - 1.3565 - 1.672 0.348 - 156.6 1 2 0 0.0016 10 0 0 0 8.66E+06 1.39E+07 - - - 3.0456 1 230117_WJC_METTL3_WT_vs_EV_F04.17227.17227.2 0.000149 13/24 K.LLLGAGAVAYGVR[166.11].E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1268.748 1.33 31718 17227 2 1268.751767 635.3813 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3425.9 - 446015 - - - 2.9478 - 2.45 0.49 - 586.3 1 2 0 0.0037 13 0 0 0 1.48E+08 1.11E+08 - - - 4.9588 0.9787 230117_WJC_METTL3_WT_vs_EV_F04.17228.17228.2 1.03 14-Jul R.MYLSLIAK.S sp|Q99959|PKP2_HUMAN 1 937.5307 0.29 31719 17228 2 937.531884 469.7726 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 8.34 3426 - 292345 - - - 1.2896 - 1.171 0.06 - 117.2 1 2 0 0.0012 8 0 0 0 4.49E+06 1.53E+07 - - - -0.0401 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17234.17234.2 0.045 14-Oct R.IVEVLLMK[136.11].D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 951.5918 0.97 31723 17234 2 951.593664 476.8032 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3426.9 - 1.21E+07 - - - 1.9326 - 2.313 0.202 - 274.6 1 2 0 0.0018 8 0 0 0 3.17E+08 3.27E+08 - - - 3.0614 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.17235.17235.2 0.0813 14-Sep R.IVEVLLMK.D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 943.5776 0.97 31724 17235 2 943.579473 472.7961 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3426.9 - 9.97E+06 - - - 1.9585 - 1.997 0.247 - 234.8 1 2 0 0.0018 8 0 0 0 3.17E+08 3.27E+08 - - - 2.9507 1 230117_WJC_METTL3_WT_vs_EV_F04.17236.17236.2 0.00488 18-Dec K.VVDLLAPYAK.G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1087.6277 1.59 31725 17236 2 1087.630865 544.8211 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3427 - 2.83E+06 - - - 2.8668 - 2.338 0.464 - 525.7 1 2 0 0.0031 10 0 0 0 4.86E+08 3.05E+08 - - - 4.8378 1 230117_WJC_METTL3_WT_vs_EV_F04.17237.17237.2 0.000602 18-Dec K.VVDLLAPYAK[136.11].G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1095.6419 1.6 31726 17237 2 1095.644831 548.8282 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3427.1 - 2.22E+06 - - - 2.6322 - 2.346 0.517 - 518.6 1 2 0 0.0029 10 0 0 0 4.90E+08 3.06E+08 - - - 5.2388 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.17245.17245.2 0.000187 16-Jul R.TFTNVYWMK.V sp|Q9HBH1|DEFM_HUMAN 1 1188.5638 1.1 31734 17245 2 1188.567264 595.2892 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 8.26 3428 - 171341 - - - 2.943 - 1.566 0.44 - 126.7 1 2 0 0.0035 9 0 0 0 5.95E+06 5.41E+06 - - - 3.5873 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.17251.17251.2 0.128 16-Jun R.AFLGQVLVR.R "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1001.6022 0.39 31738 17251 2 1001.60481 501.8084 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 9.79 3428.7 - 2.58E+06 - - - 2.6048 - 1.387 0.327 - 95.7 1 2 0 0.0026 9 0 0 0 7.27E+07 1.88E+08 - - - 2.4018 0.986 230117_WJC_METTL3_WT_vs_EV_F04.17252.17252.2 0.148 14-Jul R.LLNIWQER.S sp|Q9NQG5|RPR1B_HUMAN 1 1070.5873 2.86 31739 17252 2 1070.591394 536.3009 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 6 3428.9 - 1.33E+06 - - - 3.8437 - 1.637 0.072 - 152 1 2 0 0.0041 8 0 0 0 6.94E+07 2.42E+07 - - - 1.058 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.17255.17255.2 0.0127 16-Sep R.TPLDLAAFK.G "sp|O15084|ANR28_HUMAN,tr|B4DIW9|B4DIW9_HUMAN" 2 974.5437 1.66 31742 17255 2 974.546097 488.2791 Serine\threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5 5.5 3429.3 - 408882 - - - 2.4771 - 1.563 0.292 - 208 1 2 0 0.0024 9 0 0 0 1.62E+07 9.76E+06 - - - 2.489 0.9904 230117_WJC_METTL3_WT_vs_EV_F04.17259.17259.2 0.705 18-Aug R.LASMATLLAR.A sp|Q96P11|NSUN5_HUMAN 1 1045.5954 0.73 31745 17259 2 1045.598824 523.805 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 9.75 3429.7 - 496514 - - - 3.2737 - 1.391 0.149 - 107.6 1 2 0 0.0034 10 0 0 0 4.86E+06 6.69E+06 - - - 1.0616 0.9865 230117_WJC_METTL3_WT_vs_EV_F04.17260.17260.2 0.816 16-Jul R.IELLIDAAR[166.11].Q sp|Q8IU81|I2BP1_HUMAN 1 1022.6 1.6 31746 17260 2 1022.601834 512.3073 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.37 3429.8 - 2.43E+06 - - - 1.8267 - 1.749 0.007 - 116.8 8 2 0 0.0019 9 0 0 0 2.41E+07 1.50E+07 - - - 0.306 0.8655 230117_WJC_METTL3_WT_vs_EV_F04.17264.17264.2 1.1 12-Aug N.IC[160.03]LDILK[136.11].E "sp|O00762|UBE2C_HUMAN,sp|P61086|UBE2K_HUMAN,sp|P61088|UBE2N_HUMAN,sp|Q96LR5|UB2E2_HUMAN,sp|P51965|UB2E1_HUMAN,sp|Q969T4|UB2E3_HUMAN,sp|Q92785|REQU_HUMAN,tr|F8VSD4|F8VSD4_HUMAN,tr|B7Z306|B7Z306_HUMAN,tr|R4GND1|R4GND1_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN,tr|H7C061|H7C061_HUMAN,tr|F8VQQ8|F8VQQ8_HUMAN,tr|F8VV71|F8VV71_HUMAN,tr|A0A1B0GX65|A0A1B0GX65_HUMAN,tr|A0A087X283|A0A087X283_HUMAN,tr|H0YEI1|H0YEI1_HUMAN,tr|C9J2P0|C9J2P0_HUMAN" 18 881.5136 1.62 31750 17264 2 881.514473 441.7641 Ubiquitin-conjugating enzyme E2 C OS=Homo sapiens OX=9606 GN=UBE2C PE=1 SV=1 5.83 3430.2 - 926521 - - - 1.0187 - 1.813 0.113 - 146.2 1 1 0 0.0009 7 0 0 0 1.31E+07 8.12E+06 - - - 1.7606 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17266.17266.3 0.0177 Nov-48 K.LLLGAGAVAYGVR.E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1258.7398 1.29 31752 17266 3 1258.741399 420.5872 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3430.4 - 749834 - - - 1.3045 - 1.877 0.335 - 108.8 1 2 0 0.0016 13 0 0 0 1.21E+07 9.39E+06 - - - 3.9817 0.9962 230117_WJC_METTL3_WT_vs_EV_F04.17275.17275.2 0.0271 12-Jun R.DFYFSVK.L sp|Q9NY12|GAR1_HUMAN 1 904.4331 0.69 31759 17275 2 904.435243 453.2238 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3431.5 - 3.39E+06 - - - 2.4026 - 1.026 0.31 - 145.5 1 2 0 0.0022 7 0 0 0 6.53E+07 9.51E+07 - - - 1.4113 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.17277.17277.2 0.000163 18-Oct K.VVDDEIYYFR.K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1317.6241 2.17 31761 17277 2 1317.625079 659.8193 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3431.6 - 1.37E+06 - - - 0.7293 - 1.97 0.478 - 343.1 1 2 0 0.001 10 0 0 0 2.28E+07 1.05E+07 - - - 4.4638 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17279.17279.2 0.0135 14-Sep R.LLNIWQER[166.11].S sp|Q9NQG5|RPR1B_HUMAN 1 1080.5955 3.14 31763 17279 2 1080.597044 541.3051 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 6 3431.7 - 793157 - - - 1.3835 - 2.114 0.268 - 289.8 1 2 0 0.0015 8 0 0 0 6.88E+07 2.19E+07 - - - 3.2777 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.17288.17288.2 0.0515 14-Oct R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 3.35 31770 17288 2 1000.559941 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3432.6 - 6.42E+06 - - - 0.6077 - 1.357 0.224 - 268 1 2 0 0.0006 8 0 0 0 3.64E+07 1.09E+07 - - - 1.616 1 230117_WJC_METTL3_WT_vs_EV_F04.17289.17289.2 0.00531 16-Nov R.TPLDLAAFK[136.11].G "sp|O15084|ANR28_HUMAN,tr|B4DIW9|B4DIW9_HUMAN" 2 982.5579 1.66 31771 17289 2 982.559482 492.2862 Serine\threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5 5.5 3432.8 - 1.14E+06 - - - 1.6274 - 2.181 0.453 - 377.3 1 2 0 0.0016 9 0 0 0 1.62E+07 9.76E+06 - - - 4.6423 1 230117_WJC_METTL3_WT_vs_EV_F04.17290.17290.2 0.000201 18-Oct K.VVDDEIYYFR[166.11].K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1327.6324 2.17 31772 17290 2 1327.636515 664.8235 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3432.9 - 855825 - - - 3.1085 - 2.188 0.474 - 350.3 1 2 0 0.0041 10 0 0 0 2.28E+07 1.05E+07 - - - 4.7262 0.9941 230117_WJC_METTL3_WT_vs_EV_F04.17292.17292.2 0.282 14-Jun K.AITAATLK.F sp|P11277|SPTB1_HUMAN 1 787.4804 0.74 31774 17292 2 787.481924 394.7475 "Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB PE=1 SV=5" 8.8 3433.1 - 535896 - - - 1.9937 - 1.306 0.146 - 112.5 1 2 0 0.0016 8 0 0 0 7.24E+06 9.74E+06 - - - 0.924 0.9962 230117_WJC_METTL3_WT_vs_EV_F04.17297.17297.2 0.304 14-Aug R.AYILNLVK.Q sp|P50991|TCPD_HUMAN 1 932.5695 7.35 31778 17297 2 932.571832 467.292 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.63 3433.7 - 3.66E+07 - - - 2.4963 - 1.364 0.2 - 221.2 1 2 0 0.0023 8 0 0 0 1.20E+09 1.63E+08 - - - 1.4537 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.17301.17301.2 0.0724 16-Jun R.MLPPPPMWR[166.11].R "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 5 1133.5753 0.7 31782 17301 2 1133.577936 567.795 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 9.5 3434.1 - 596876 - - - 2.283 - 1.244 0.259 - 111.6 1 2 0 0.0026 9 0 0 0 1.19E+07 1.71E+07 - - - 1.5848 0.9963 230117_WJC_METTL3_WT_vs_EV_F04.17302.17302.2 0.233 12-Jun R.VLFSLVK.R "sp|Q14999|CUL7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 2 804.5109 0.87 31783 17302 2 804.511804 403.2627 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 8.72 3434.2 - 359965 - - - 1.0913 - 1.259 0.197 - 125.2 1 2 0 0.0009 7 0 0 0 6.31E+06 7.24E+06 - - - 1.2255 0.999 230117_WJC_METTL3_WT_vs_EV_F04.17305.17305.2 3.67E-05 22-Sep R.YVVGVLEAAGVR[166.11].Y sp|Q9H9S5|FKRP_HUMAN 1 1241.7007 0.42 31784 17305 2 1241.70312 621.8576 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 6 3434.6 - 625884 - - - 1.9151 - 1.883 0.232 - 234.3 1 2 0 0.0024 12 0 0 0 7.33E+06 1.74E+07 - - - 2.419 1 230117_WJC_METTL3_WT_vs_EV_F04.17307.17307.2 2.77E-05 18-Dec K.WVGVILDEAK.G "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1128.6179 3.29 31785 17307 2 1128.620367 565.3162 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3434.8 - 2.52E+06 - - - 2.177 - 2.363 0.485 - 520.6 1 2 0 0.0025 10 0 0 0 1.44E+08 4.38E+07 - - - 5.0228 1 230117_WJC_METTL3_WT_vs_EV_F04.17311.17311.2 1.38E-06 22-Nov R.YVVGVLEAAGVR.Y sp|Q9H9S5|FKRP_HUMAN 1 1231.6925 0.42 31789 17311 2 1231.693783 616.8535 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 6 3435.2 - 1.80E+06 - - - 1.0644 - 2.221 0.573 - 281.8 1 2 0 0.0013 12 0 0 0 7.33E+06 1.74E+07 - - - 5.3723 0.999 230117_WJC_METTL3_WT_vs_EV_F04.17313.17313.2 0.044 18-Dec K.VALAVSLNLR.T "sp|Q03426|KIME_HUMAN,tr|F5GXC0|F5GXC0_HUMAN,tr|F5H163|F5H163_HUMAN,tr|F5H092|F5H092_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|F5H368|F5H368_HUMAN,tr|A0A1W2PS16|A0A1W2PS16_HUMAN" 7 1054.6499 1.11 31791 17313 2 1054.65407 528.3322 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 9.72 3435.4 - 957192 - - - 3.9738 - 2.451 0.357 - 415 1 2 0 0.0042 10 0 0 0 4.85E+06 4.36E+06 - - - 4.1789 1 230117_WJC_METTL3_WT_vs_EV_F04.17314.17314.2 6.56E-05 14/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 4.01 31792 17314 2 1484.908047 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3435.5 - 825302 - - - 0.1091 - 2.421 0.551 - 495.8 1 2 0 0.0002 15 0 0 0 2.49E+07 6.21E+06 - - - 5.2844 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.17319.17319.2 0.00258 16-Nov R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.98 31795 17319 2 989.594584 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3436.2 - 1.89E+06 - - - 3.655 - 2.227 0.408 - 313.9 1 2 0 0.0036 9 0 0 0 3.20E+09 3.27E+09 - - - 4.3697 1 230117_WJC_METTL3_WT_vs_EV_F04.17321.17321.2 0.00126 16-Nov R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 0.98 31797 17321 2 997.606639 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3436.4 - 3.18E+06 - - - 1.4755 - 2.322 0.421 - 306.9 1 2 0 0.0015 9 0 0 0 3.20E+09 3.26E+09 - - - 4.5872 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17324.17324.2 0.00134 18-Nov K.WTETEIEMLR.A "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 1306.6227 0.27 31800 17324 2 1306.625111 654.3186 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 4.25 3436.7 - 296427 - - - 1.8161 - 1.885 0.416 - 478.3 1 2 0 0.0024 10 0 0 0 2.42E+06 9.02E+06 - - - 3.8823 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17331.17331.2 0.00635 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 2.66 31805 17331 2 1006.573106 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3437.6 - 3.01E+06 - - - 3.1871 - 1.871 0.449 - 252.2 1 2 0 0.0032 9 0 0 0 6.55E+06 2.46E+06 - - - 4.1687 0.9963 230117_WJC_METTL3_WT_vs_EV_F04.17332.17332.2 0.0518 18-Oct K.VALAVSLNLR[166.11].T "sp|Q03426|KIME_HUMAN,tr|F5GXC0|F5GXC0_HUMAN,tr|F5H163|F5H163_HUMAN,tr|F5H092|F5H092_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|F5H368|F5H368_HUMAN,tr|A0A1W2PS16|A0A1W2PS16_HUMAN" 7 1064.6581 1.11 31806 17332 2 1064.66169 533.3364 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 9.72 3437.7 - 1.59E+06 - - - 3.326 - 1.73 0.179 - 279.9 1 2 0 0.0035 10 0 0 0 4.85E+06 4.36E+06 - - - 1.892 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17333.17333.2 0.00115 18-Sep R.VVLPIEAPIR.M sp|P00403|COX2_HUMAN 1 1105.6859 1.6 31807 17333 2 1105.688632 553.8502 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 5.97 3437.9 - 1.61E+06 - - - 2.4437 - 1.737 0.41 - 319.4 1 2 0 0.0027 10 0 0 0 5.85E+08 3.65E+08 - - - 3.6097 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17335.17335.2 0.000565 18-Nov R.VVLPIEAPIR[166.11].M sp|P00403|COX2_HUMAN 1 1115.6942 1.6 31809 17335 2 1115.696747 558.8544 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 5.97 3438.1 - 1.30E+06 - - - 2.2829 - 2.028 0.402 - 495.4 1 2 0 0.0025 10 0 0 0 5.85E+08 3.65E+08 - - - 3.983 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.17336.17336.2 0.0584 18-Oct R.FSNLLGTVYR[166.11].R "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN,tr|C9J544|C9J544_HUMAN" 3 1178.6323 1.03 31810 17336 2 1178.635383 590.3234 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 8.75 3438.2 - 1.08E+06 - - - 2.592 - 1.98 0.271 - 341.2 1 2 0 0.0031 10 0 0 0 6.34E+06 6.18E+06 - - - 2.9484 0.998 230117_WJC_METTL3_WT_vs_EV_F04.17337.17337.2 0.0201 18-Aug R.LLFNDVQTLK.D "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1189.6707 1 31811 17337 2 1189.675501 595.8426 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.84 3438.4 - 1.03E+06 - - - 4.0574 - 1.769 0.337 - 166 1 2 0 0.0048 10 0 0 0 2.03E+07 2.02E+07 - - - 3.1208 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17338.17338.2 0.0045 18-Sep R.LLFNDVQTLK[136.11].D "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1197.6849 1 31812 17338 2 1197.68685 599.8497 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.84 3438.5 - 1.00E+06 - - - 1.6498 - 2 0.333 - 192.7 1 2 0 0.002 10 0 0 0 2.03E+07 2.02E+07 - - - 3.4347 1 230117_WJC_METTL3_WT_vs_EV_F04.17339.17339.2 0.000144 15/22 R.LGASLAFNNIYR.E sp|P78527|PRKDC_HUMAN 1 1337.7092 1.1 31813 17339 2 1337.711286 669.8619 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.75 3438.6 - 927596 - - - 1.5706 - 3.123 0.49 - 991.8 1 2 0 0.0021 12 0 0 0 4.12E+06 3.76E+06 - - - 5.6558 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.17340.17340.2 0.0107 14-Aug K.FYFEELGK[136.11].Y sp|Q10471|GALT2_HUMAN 1 1039.5106 0.96 31814 17340 2 1039.51228 520.7626 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3438.8 - 862951 - - - 1.6181 - 1.423 0.32 - 180.1 1 2 0 0.0017 8 0 0 0 3.95E+07 4.13E+07 - - - 2.4679 1 230117_WJC_METTL3_WT_vs_EV_F04.17343.17343.2 2.33E-06 15/28 R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 5.11 31817 17343 2 1494.917833 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3439.2 - 602556 - - - 1.1225 - 2.452 0.556 - 572.6 1 2 0 0.0017 15 0 0 0 3.74E+07 7.32E+06 - - - 5.3522 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17347.17347.2 0.138 14-Sep K.IDLTLLNR[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 966.5738 1.17 31820 17347 2 966.575612 484.2942 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.84 3439.6 - 4.62E+06 - - - 1.9254 - 2.096 0.27 - 249.9 1 2 0 0.0019 8 0 0 0 6.72E+07 5.75E+07 - - - 3.2665 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17348.17348.2 0.154 18-Oct K.IYVISLAEPR.L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1159.6601 1.45 31821 17348 2 1159.662941 580.8373 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3439.8 - 897113 - - - 2.4412 - 2.131 0.39 - 448.8 1 2 0 0.0028 10 0 0 0 1.46E+08 1.01E+08 - - - 4.0325 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.17350.17350.2 0.045 16-Sep K.VVLPC[160.03]NLLR[166.11].M "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1092.6353 9.74 31823 17350 2 1092.636273 547.3249 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 8.22 3439.9 - 1.78E+06 - - - 0.885 - 1.503 0.363 - 341 1 2 0 0.001 9 0 0 0 4.55E+08 4.67E+07 - - - 2.9006 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17351.17351.2 0.000436 20-Oct R.FLPEFAGTQLK.L sp|Q9UBZ4|APEX2_HUMAN 1 1249.6707 1.07 31824 17351 2 1249.672978 625.8426 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 6 3440 - 1.50E+06 - - - 1.8437 - 1.735 0.371 - 342.4 1 2 0 0.0023 11 0 0 0 5.36E+07 5.03E+07 - - - 3.2711 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.17354.17354.2 0.0499 18-Jul K.IYVISLAEPR[166.11].L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1169.6684 1.45 31827 17354 2 1169.670873 585.8415 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3440.3 - 796997 - - - 2.1314 - 1.769 0.241 - 163.6 2 2 0 0.0025 10 0 0 0 1.46E+08 1.01E+08 - - - 2.278 1 230117_WJC_METTL3_WT_vs_EV_F04.17355.17355.2 0.000207 13/22 R.LNVGGTYFLTTR[166.11].Q "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1350.7171 0.39 31828 17355 2 1350.719093 676.3658 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3440.4 - 564930 - - - 1.46 - 2.296 0.498 - 523.9 1 2 0 0.002 12 0 0 0 4.36E+06 1.11E+07 - - - 4.9056 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17360.17360.2 0.109 14-Oct K.IDLTLLNR.L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 956.5655 1.18 31832 17360 2 956.56665 479.29 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.84 3441 - 9.35E+06 - - - 1.2221 - 2.189 0.319 - 354 1 2 0 0.0012 8 0 0 0 6.70E+07 5.67E+07 - - - 3.7596 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.17362.17362.2 1.31E-05 20-Sep R.FLPEFAGTQLK[136.11].L sp|Q9UBZ4|APEX2_HUMAN 1 1257.6849 1.07 31833 17362 2 1257.682681 629.8497 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 6 3441.2 - 2.92E+06 - - - -1.7437 - 1.768 0.511 - 321.1 1 2 0 -0.0022 11 0 0 0 5.36E+07 5.03E+07 - - - 4.3561 0.9881 230117_WJC_METTL3_WT_vs_EV_F04.17374.17374.2 0.233 12-Jun K.FIDPFC[160.03]R[166.11].L sp|P56182|RRP1_HUMAN 1 963.4512 0.9 31842 17374 2 963.448738 482.7329 Ribosomal RNA processing protein 1 homolog A OS=Homo sapiens OX=9606 GN=RRP1 PE=1 SV=1 5.83 3442.5 - 1.19E+06 - - - -2.5481 - 1.251 0.29 - 92.2 1 2 0 -0.0025 7 0 0 0 1.43E+07 1.58E+07 - - - 1.8917 0.9957 230117_WJC_METTL3_WT_vs_EV_F04.17381.17381.2 0.846 18-Jul K.FLALEGNPLR[166.11].T sp|Q9H9A6|LRC40_HUMAN 1 1138.6374 3.24 31846 17381 2 1138.640225 570.326 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 6 3443.3 - 1.82E+06 - - - 2.4687 - 1.262 0.221 - 130.1 1 2 0 0.0028 10 0 0 0 7.25E+07 2.24E+07 - - - 1.322 0.9949 230117_WJC_METTL3_WT_vs_EV_F04.17389.17389.2 0.0119 12-May K.FIDPFC[160.03]R.L sp|P56182|RRP1_HUMAN 1 953.4429 0.97 31852 17389 2 953.441176 477.7287 Ribosomal RNA processing protein 1 homolog A OS=Homo sapiens OX=9606 GN=RRP1 PE=1 SV=1 5.83 3444.1 - 766290 - - - -1.8323 - 1.136 0.384 - 92.2 1 2 0 -0.0017 7 0 0 0 1.54E+07 1.58E+07 - - - 2.2807 1 230117_WJC_METTL3_WT_vs_EV_F04.17405.17405.2 0.000704 16-Nov R.PLVALLDGR.D "sp|P56545|CTBP2_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|E7ESU7|E7ESU7_HUMAN,tr|E7EUB3|E7EUB3_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|E7EPF8|E7EPF8_HUMAN,tr|E9PGB1|E9PGB1_HUMAN" 7 952.5706 1.81 31861 17405 2 952.562844 477.2926 C-terminal-binding protein 2 OS=Homo sapiens OX=9606 GN=CTBP2 PE=1 SV=1 6.27 3446.2 - 935680 - - - -8.1065 - 2.336 0.435 - 513.5 1 1 0 -0.0077 9 0 0 0 8.68E+07 4.79E+07 - - - 4.7061 1 230117_WJC_METTL3_WT_vs_EV_F04.17409.17409.2 1.14E-08 13/20 R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 999 31863 17409 2 1201.607033 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3446.7 - 899650 - - - -1.751 - 2.481 0.582 - 826.4 1 2 0 -0.0021 11 0 0 0 1.73E+07 0.00E+00 - - - 5.7971 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.17418.17418.2 0.219 14-Aug R.GIFEPFGK.L "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 893.4647 0.71 31867 17418 2 893.46557 447.7396 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 6 3447.7 - 0 - - - 0.9693 - 1.422 0.273 - 210 1 2 0 0.0009 8 0 0 0 1.21E+08 1.70E+08 - - - 2.1189 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17428.17428.2 0.00487 16-Nov K.IAFAITAIK.G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 946.5852 1.18 31873 17428 2 946.584662 474.2999 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3448.9 - 1.35E+06 - - - -0.5198 - 2.3 0.368 - 308.7 1 2 0 -0.0005 9 0 0 0 4.69E+09 3.97E+09 - - - 4.1685 1 230117_WJC_METTL3_WT_vs_EV_F04.17436.17436.2 4.27E-05 14/20 R.MGPGIGAILER.S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1112.6012 2.24 31875 17436 2 1112.598215 557.3079 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.75 3450.1 - 3.71E+06 - - - -2.6955 - 2.419 0.513 - 687.2 1 2 0 -0.003 11 0 0 0 1.99E+08 8.89E+07 - - - 5.2188 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.17438.17438.2 0.0555 16-Nov K.IAFAITAIK[136.11].G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 954.5994 1.18 31876 17438 2 954.602981 478.307 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3450.4 - 9.72E+06 - - - 3.7995 - 2.279 0.284 - 260.7 1 2 0 0.0036 9 0 0 0 4.69E+09 3.97E+09 - - - 3.5206 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.17442.17442.2 0.0717 18-Sep R.LGLPGEVFGR[166.11].S sp|O95409|ZIC2_HUMAN 1 1053.5847 2.44 31878 17442 2 1053.58469 527.7996 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 6 3450.9 - 2.22E+06 - - - 0.038 - 1.524 0.305 - 162.4 1 2 0 0 10 0 0 0 2.92E+08 1.19E+08 - - - 2.4698 0.9621 230117_WJC_METTL3_WT_vs_EV_F04.17465.17465.2 0.0347 14-Aug R.FLDDLGLK.F sp|Q14126|DSG2_HUMAN 1 919.5015 1.8 31888 17465 2 919.495597 460.758 Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2 4.21 3453.8 - 3.67E+06 - - - -6.4024 - 1.675 0.359 - 173 1 2 0 -0.0059 8 0 0 0 4.18E+07 2.32E+07 - - - 3.2464 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.17466.17466.2 0.0172 13/20 R.ALTALGLAVPR.G sp|Q9BVQ7|SPA5L_HUMAN 1 1080.6655 12.92 31889 17466 2 1080.663912 541.34 Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2 9.79 3453.9 - 1.95E+06 - - - -1.4963 - 2.573 0.301 - 749.8 1 2 0 -0.0016 11 0 0 0 3.39E+07 2.62E+06 - - - 3.8203 0.9887 230117_WJC_METTL3_WT_vs_EV_F04.17476.17476.2 0.0972 16-Sep K.IFTQLEEFR[166.11].A sp|O60306|AQR_HUMAN 1 1191.6163 0.89 31893 17476 2 1191.610379 596.8154 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 4.53 3455.2 - 0 - - - -5.0058 - 1.918 0.399 - 290.1 1 2 0 -0.006 9 0 0 0 1.35E+07 1.52E+07 - - - 3.8703 0.9839 230117_WJC_METTL3_WT_vs_EV_F04.17481.17481.2 0.00764 16-Sep K.SALLALGLK.C sp|Q12874|SF3A3_HUMAN 1 884.5695 3.41 31895 17481 2 884.565221 443.292 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3455.8 - 1.35E+06 - - - -4.8419 - 1.838 0.315 - 252.5 1 2 0 -0.0043 9 0 0 0 2.49E+08 7.31E+07 - - - 3.1272 0.999 230117_WJC_METTL3_WT_vs_EV_F04.17488.17488.2 0.00417 16-Sep K.ALQFLEEVK.V sp|P40227|TCPZ_HUMAN 1 1075.5914 10.33 31899 17488 2 1075.59098 538.803 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 3456.7 - 1.40E+06 - - - -0.3542 - 1.791 0.325 - 214.2 1 2 0 -0.0004 9 0 0 0 4.71E+07 4.56E+06 - - - 3.1273 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17490.17490.2 0.000427 18-Oct R.FQSLGVAFYR.G "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1186.6135 1.62 31901 17490 2 1186.613942 594.314 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 8.75 3457 - 616836 - - - 0.3775 - 2.014 0.417 - 310.8 1 2 0 0.0004 10 0 0 0 4.67E+07 2.87E+07 - - - 4.0751 0.9958 230117_WJC_METTL3_WT_vs_EV_F04.17495.17495.2 0.14 12-Jun K.ELEFYLR.K "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 968.4967 0.88 31903 17495 2 968.497789 485.2556 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.53 3457.6 - 3.21E+06 - - - 1.0903 - 1.183 0.208 - 249.2 1 2 0 0.0011 7 0 0 0 3.09E+08 3.51E+08 - - - 1.1094 0.9967 230117_WJC_METTL3_WT_vs_EV_F04.17496.17496.2 0.0532 16-Sep K.SALLALGLK[136.11].C sp|Q12874|SF3A3_HUMAN 1 892.5837 3.41 31904 17496 2 892.587961 447.2991 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3457.7 - 903878 - - - 4.7693 - 1.964 0.281 - 264.4 1 2 0 0.0043 9 0 0 0 2.49E+08 7.31E+07 - - - 3.0679 0.9852 230117_WJC_METTL3_WT_vs_EV_F04.17498.17498.2 2.98 14-Aug K.GLGILSLK[136.11].Q sp|Q92616|GCN1_HUMAN 1 807.5309 0.84 31906 17498 2 807.529373 404.7727 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.75 3458 - 274968 - - - -1.9405 - 1.413 0.174 - 196 1 2 0 -0.0016 8 0 0 0 3.79E+07 4.52E+07 - - - 1.3683 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.17501.17501.2 3.07E-05 18-Nov R.FQSLGVAFYR[166.11].G "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1196.6218 1.62 31907 17501 2 1196.622534 599.3182 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 8.75 3458.4 - 527111 - - - 0.6435 - 2.079 0.433 - 357.7 1 2 0 0.0008 10 0 0 0 4.67E+07 2.87E+07 - - - 4.2818 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17513.17513.2 0.114 18-Aug R.LGLPGEVFGR.S sp|O95409|ZIC2_HUMAN 1 1043.5764 2.44 31912 17513 2 1043.577071 522.7955 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 6 3459.9 - 1.27E+06 - - - 0.6621 - 1.898 0.376 - 165.4 1 2 0 0.0007 10 0 0 0 2.92E+08 1.19E+08 - - - 3.6066 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17514.17514.2 0.000294 20-Nov K.FSPAGPILSIR[166.11].L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1166.6687 1.04 31913 17514 2 1166.670378 584.3416 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3460.1 - 959471 - - - 1.4263 - 1.995 0.368 - 484.6 1 2 0 0.0017 11 0 0 0 6.90E+08 6.65E+08 - - - 3.6269 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.17518.17518.2 0.00045 20-Sep K.FSPAGPILSIR.L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1156.6604 1.04 31915 17518 2 1156.658973 579.3375 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3460.6 - 3.37E+06 - - - -1.2718 - 1.856 0.317 - 297.7 1 2 0 -0.0015 11 0 0 0 6.90E+08 6.65E+08 - - - 3.0549 0.9437 230117_WJC_METTL3_WT_vs_EV_F04.17519.17519.2 0.0035 18-Sep D.TLDNDIMLIK.L "sp|P35030|TRY3_HUMAN,tr|A0A7P0MNE9|A0A7P0MNE9_HUMAN" 2 1174.6268 24.95 31916 17519 2 1174.626357 588.3207 Trypsin-3 OS=Homo sapiens OX=9606 GN=PRSS3 PE=1 SV=2 4.21 3460.6 - 1.44E+06 - - - -0.3439 - 1.623 0.42 - 168.4 1 1 0 -0.0004 10 0 0 0 9.32E+07 3.73E+06 - - - 3.4948 0.9834 230117_WJC_METTL3_WT_vs_EV_F04.17520.17520.2 0.000225 20-Aug K.LGNPIVPLNIR[166.11].L sp|P78527|PRKDC_HUMAN 1 1214.7375 0.91 31917 17520 2 1214.732957 608.376 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3460.8 - 0 - - - -3.7086 - 1.602 0.264 - 217.6 1 2 0 -0.0045 11 0 0 0 1.09E+07 1.20E+07 - - - 2.2643 0.9811 230117_WJC_METTL3_WT_vs_EV_F04.17522.17522.2 2.69 12-May K.QFLLLSR.Q sp|Q5T447|HECD3_HUMAN 1 875.5229 1.23 31919 17522 2 875.523699 438.7687 E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens OX=9606 GN=HECTD3 PE=1 SV=1 9.75 3461 - 0 - - - 0.9263 - 1.343 0.012 - 109.1 1 2 0 0.0008 7 0 0 0 3.74E+06 3.04E+06 - - - 0.0638 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.17530.17530.2 0.105 14-Aug K.IIDFGLAR.R "sp|Q86YV6|MYLK4_HUMAN,sp|Q32MK0|MYLK3_HUMAN,sp|Q9H1R3|MYLK2_HUMAN,sp|P53778|MK12_HUMAN,sp|O15264|MK13_HUMAN,sp|P45983|MK08_HUMAN,sp|Q16539|MK14_HUMAN,sp|P45984|MK09_HUMAN,sp|Q15759|MK11_HUMAN,sp|P53779|MK10_HUMAN,sp|Q15746|MYLK_HUMAN,tr|A0A286YFD7|A0A286YFD7_HUMAN,tr|A0A286YES0|A0A286YES0_HUMAN,tr|A0A286YEQ0|A0A286YEQ0_HUMAN,tr|A0A286YEX7|A0A286YEX7_HUMAN,tr|A0A286YFC0|A0A286YFC0_HUMAN,tr|B5MDL5|B5MDL5_HUMAN,tr|A0A286YES9|A0A286YES9_HUMAN,tr|A0A286YF97|A0A286YF97_HUMAN,tr|D6RCB1|D6RCB1_HUMAN,tr|A0A286YF19|A0A286YF19_HUMAN,tr|A0A286YFN2|A0A286YFN2_HUMAN,tr|D6RJF9|D6RJF9_HUMAN,tr|A0A286YEY0|A0A286YEY0_HUMAN,tr|Q5R3E6|Q5R3E6_HUMAN,tr|A0A286YEV8|A0A286YEV8_HUMAN,tr|B4E0K5|B4E0K5_HUMAN,tr|A0A286YF85|A0A286YF85_HUMAN,tr|A0A286YFI3|A0A286YFI3_HUMAN,tr|F8W9R5|F8W9R5_HUMAN,tr|A0A2R8Y4U5|A0A2R8Y4U5_HUMAN,tr|A0A286YFM6|A0A286YFM6_HUMAN,tr|A0A286YEV3|A0A286YEV3_HUMAN,tr|A0A286YF83|A0A286YF83_HUMAN,tr|A0A286YFJ6|A0A286YFJ6_HUMAN,tr|A0A286YF62|A0A286YF62_HUMAN,tr|A0A286YF02|A0A286YF02_HUMAN,tr|J3KNK1|J3KNK1_HUMAN,tr|A0A286YEQ7|A0A286YEQ7_HUMAN,tr|A0A286YFJ4|A0A286YFJ4_HUMAN,tr|A0A1W2PPZ3|A0A1W2PPZ3_HUMAN,tr|A0A286YEN5|A0A286YEN5_HUMAN,tr|A0A286YFA6|A0A286YFA6_HUMAN,tr|A0A1P0B7D2|A0A1P0B7D2_HUMAN,tr|A0A1W2PRF2|A0A1W2PRF2_HUMAN,tr|D7R525|D7R525_HUMAN,tr|A0A286YF35|A0A286YF35_HUMAN,tr|A0A286YFB6|A0A286YFB6_HUMAN,tr|A0A286YFE2|A0A286YFE2_HUMAN,tr|A0A286YEW9|A0A286YEW9_HUMAN,tr|E7EX54|E7EX54_HUMAN" 51 903.5178 3.26 31924 17530 2 903.519487 452.7662 Myosin light chain kinase family member 4 OS=Homo sapiens OX=9606 GN=MYLK4 PE=1 SV=2 5.84 3462.1 - 686826 - - - 1.8649 - 1.64 0.149 - 170.2 1 2 0 0.0017 8 0 0 0 3.10E+07 9.50E+06 - - - 1.633 0.9941 230117_WJC_METTL3_WT_vs_EV_F04.17539.17539.2 0.00207 14-Jul R.GLFIIDGK.G sp|P32119|PRDX2_HUMAN 1 861.496 2.47 31930 17539 2 861.49428 431.7553 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3463.2 - 875864 - - - -2.0012 - 1.487 0.27 - 192 1 2 0 -0.0017 8 0 0 0 3.83E+08 1.55E+08 - - - 2.2313 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.17544.17544.2 0.00357 14-Aug R.GLFIIDGK[136.11].G sp|P32119|PRDX2_HUMAN 1 869.5102 2.44 31933 17544 2 869.509324 435.7624 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3463.8 - 1.12E+06 - - - -1.0121 - 1.508 0.341 - 275.6 1 2 0 -0.0009 8 0 0 0 3.77E+08 1.55E+08 - - - 2.7983 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17546.17546.2 0.00336 20-Sep K.LGNPIVPLNIR.L sp|P78527|PRKDC_HUMAN 1 1204.7292 0.91 31935 17546 2 1204.73241 603.3719 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3464 - 621709 - - - 2.6711 - 1.895 0.411 - 295.6 1 2 0 0.0032 11 0 0 0 1.09E+07 1.20E+07 - - - 3.8049 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17549.17549.2 7.11E-05 20-Dec K.VLADLAIYEPK[136.11].T sp|Q9BYC9|RM20_HUMAN 1 1238.7002 1.08 31938 17549 2 1238.703152 620.3574 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3464.4 - 393360 - - - 2.3912 - 2.187 0.372 - 362.5 1 2 0 0.003 11 0 0 0 1.68E+07 1.55E+07 - - - 3.9046 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.17552.17552.2 0.000326 18-Sep K.LLYPLQEVER[166.11].F "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 1268.7004 1.06 31941 17552 2 1268.706801 635.3575 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.53 3464.8 - 303208 - - - 5.039 - 1.839 0.454 - 321.3 1 2 0 0.0064 10 0 0 0 8.29E+06 7.82E+06 - - - 4.0928 1 230117_WJC_METTL3_WT_vs_EV_F04.17558.17558.2 8.07E-07 18-Dec K.VGDQILLAIK[136.11].G sp|Q6P1L8|RM14_HUMAN 1 1076.6685 1.75 31945 17558 2 1076.667908 539.3415 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3465.5 - 2.86E+06 - - - -0.5461 - 2.579 0.489 - 506.4 1 2 0 -0.0006 10 0 0 0 8.01E+07 4.57E+07 - - - 5.2971 1 230117_WJC_METTL3_WT_vs_EV_F04.17560.17560.2 8.17E-06 18-Nov K.VGDQILLAIK.G sp|Q6P1L8|RM14_HUMAN 1 1068.6543 1.75 31946 17560 2 1068.653139 535.3344 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3465.7 - 2.07E+06 - - - -1.0827 - 2.276 0.518 - 450.6 1 2 0 -0.0012 10 0 0 0 8.01E+07 4.57E+07 - - - 5.1622 1 230117_WJC_METTL3_WT_vs_EV_F04.17561.17561.2 2.29E-07 18-Nov K.LGDDIDLIVR.C sp|O15371|EIF3D_HUMAN 1 1127.6186 1.1 31947 17561 2 1127.614344 564.8166 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3465.8 - 1.46E+06 - - - -3.8089 - 2.424 0.507 - 328.7 1 2 0 -0.0043 10 0 0 0 2.43E+08 2.22E+08 - - - 5.2558 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.17562.17562.2 0.096 13/20 K.VLADLAIYEPK.T sp|Q9BYC9|RM20_HUMAN 1 1230.686 1.08 31948 17562 2 1230.685474 616.3503 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3465.9 - 997644 - - - -0.4193 - 2.067 0.342 - 285.4 1 2 0 -0.0005 11 0 0 0 1.68E+07 1.55E+07 - - - 3.5311 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17563.17563.2 0.00188 14-Sep R.GPIAFWAR[166.11].R "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H909|Q5H909_HUMAN" 2 926.5002 1.03 31949 17563 2 926.502724 464.2574 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 9.75 3466 - 990928 - - - 2.7329 - 1.862 0.387 - 287 1 2 0 0.0025 8 0 0 0 1.28E+07 1.25E+07 - - - 3.7735 1 230117_WJC_METTL3_WT_vs_EV_F04.17564.17564.2 4.82E-05 15/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 5.92 31950 17564 2 1484.910426 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3466.2 - 699764 - - - 1.7112 - 2.628 0.588 - 567.9 1 2 0 0.0025 15 0 0 0 7.88E+07 1.33E+07 - - - 5.7587 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17567.17567.2 0.0458 16-Oct R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.91 31952 17567 2 989.591699 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3466.5 - 2.03E+06 - - - 0.7397 - 2.232 0.33 - 264.7 1 2 0 0.0007 9 0 0 0 1.79E+08 1.98E+08 - - - 3.801 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17569.17569.2 0.00816 16-Nov R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 0.91 31953 17569 2 997.607782 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3466.7 - 1.79E+06 - - - 2.6213 - 2.322 0.411 - 318.9 1 2 0 0.0026 9 0 0 0 1.84E+08 2.01E+08 - - - 4.513 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.17571.17571.2 0.201 18-Aug K.ALLAEGVILR.R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1053.6546 1.38 31955 17571 2 1053.657221 527.8346 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3466.9 - 976227 - - - 2.4591 - 1.787 0.243 - 141.9 1 2 0 0.0026 10 0 0 0 2.52E+08 1.83E+08 - - - 2.4554 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.17572.17572.2 0.152 12-Jul K.SLDIFIK.A sp|Q9H583|HEAT1_HUMAN 1 834.4851 0.59 31956 17572 2 834.486702 418.2498 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.55 3467.1 - 720183 - - - 1.9138 - 1.478 0.18 - 180.8 1 2 0 0.0016 7 0 0 0 1.00E+07 1.70E+07 - - - 1.6079 0.9307 230117_WJC_METTL3_WT_vs_EV_F04.17575.17575.2 0.0286 13/16 S.PAGPILSIR[166.11].L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 932.5683 0.65 31959 17575 2 932.5684 467.2914 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 10.18 3467.4 - 410401 - - - 0.1373 - 2.306 0.184 - 492.8 1 1 0 0.0001 9 0 0 0 3.50E+06 5.41E+06 - - - 2.8172 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.17578.17578.2 0.0113 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 10706.49 31960 17578 2 1006.570601 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3467.8 - 1.36E+08 - - - 0.6984 - 1.937 0.477 - 258.2 1 2 0 0.0007 9 0 0 0 2.11E+11 1.97E+07 - - - 4.4766 0.982 230117_WJC_METTL3_WT_vs_EV_F04.17579.17579.2 0.729 14-Aug K.AFLNAIMR.Y "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|K7EMY3|K7EMY3_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 23 934.5059 0.65 31961 17579 2 934.508619 468.2602 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.79 3467.9 - 278223 - - - 2.9556 - 1.254 0.1 - 140 1 2 0 0.0028 8 0 0 0 7.95E+06 1.22E+07 - - - 0.4614 1 230117_WJC_METTL3_WT_vs_EV_F04.17581.17581.2 0.000612 20-Oct R.LLYC[160.03]TTGVLLR.R "sp|Q6P158|DHX57_HUMAN,sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 3 1307.7271 0.54 31963 17581 2 1307.732122 654.8708 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 8.22 3468.2 - 164184 - - - 3.8066 - 2.239 0.473 - 430.7 1 2 0 0.005 11 0 0 0 7.16E+06 1.33E+07 - - - 4.7135 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.17584.17584.2 0.0483 12-Jun R.IIFDDFR.E sp|P46977|STT3A_HUMAN 1 924.4705 1.11 31964 17584 2 924.469677 463.2425 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.21 3468.6 - 1.08E+06 - - - -0.9097 - 1.167 0.393 - 95.5 1 2 0 -0.0008 7 0 0 0 1.09E+08 9.82E+07 - - - 2.4328 0.998 230117_WJC_METTL3_WT_vs_EV_F04.17586.17586.2 0.64 18-Dec K.ALLAEGVILR[166.11].R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1063.6629 1.38 31965 17586 2 1063.662697 532.8387 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3468.8 - 990394 - - - -0.1908 - 1.908 0.181 - 678.5 1 2 0 -0.0002 10 0 0 0 2.52E+08 1.83E+08 - - - 2.1811 0.9831 230117_WJC_METTL3_WT_vs_EV_F04.17587.17587.2 7.72 14-Jul R.NLLTGLVR[166.11].H "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 894.5526 1.26 31966 17587 2 894.553808 448.2836 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 9.75 3468.9 - 182704 - - - 1.3269 - 1.368 0.017 - 176.8 1 2 0 0.0012 8 0 0 0 1.36E+08 1.08E+08 - - - 0.1112 0.9881 230117_WJC_METTL3_WT_vs_EV_F04.17588.17588.2 0.371 12-Jun R.IIFDDFR[166.11].E sp|P46977|STT3A_HUMAN 1 934.4788 1.12 31967 17588 2 934.477567 468.2467 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.21 3468.9 - 956633 - - - -1.3066 - 1.076 0.264 - 85.8 1 2 0 -0.0012 7 0 0 0 1.08E+08 9.61E+07 - - - 1.2226 1 230117_WJC_METTL3_WT_vs_EV_F04.17594.17594.2 5.20E-06 28-Nov R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 4.99 31972 17594 2 1494.91806 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3469.6 - 259874 - - - 1.2743 - 2.122 0.531 - 337.8 1 2 0 0.0019 15 0 0 0 2.91E+07 5.82E+06 - - - 4.8121 0.9958 230117_WJC_METTL3_WT_vs_EV_F04.17596.17596.2 2.6 14-Jul R.NLLTGLVR.H "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 884.5444 1.22 31973 17596 2 884.545012 443.2795 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 9.75 3469.9 - 2.03E+06 - - - 0.7473 - 1.256 0.196 - 168.6 1 2 0 0.0007 8 0 0 0 1.29E+08 1.06E+08 - - - 1.1759 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17597.17597.2 0.0181 14-Sep R.LLNVWQVR.S "sp|Q15061|WDR43_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 2 1026.5974 1.16 31974 17597 2 1026.59767 514.306 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 9.75 3470 - 1.37E+06 - - - 0.2143 - 1.883 0.35 - 291.5 1 2 0 0.0002 8 0 0 0 5.46E+07 4.69E+07 - - - 3.5347 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17599.17599.2 0.00308 18-Nov R.IAEFAFEYAR.N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1215.5924 2.37 31976 17599 2 1215.593854 608.8035 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3470.2 - 1.26E+06 - - - 1.1764 - 2.413 0.292 - 528.1 1 2 0 0.0014 10 0 0 0 2.93E+07 1.23E+07 - - - 3.656 0.9918 230117_WJC_METTL3_WT_vs_EV_F04.17600.17600.2 0.0864 12-Jul R.LFLEFER[166.11].K "sp|O43663|PRC1_HUMAN,sp|Q96I25|SPF45_HUMAN,tr|H0YL53|H0YL53_HUMAN" 3 962.5101 0.74 31977 17600 2 962.513289 482.2623 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 3470.3 - 872958 - - - 3.3257 - 1.595 0.112 - 154.6 2 2 0 0.0032 7 0 0 0 1.92E+07 2.59E+07 - - - 1.2121 0.984 230117_WJC_METTL3_WT_vs_EV_F04.17601.17601.2 0.573 12-Jul K.DFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 834.46 0.65 31978 17601 2 834.458381 418.2373 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.84 3470.4 - 413561 - - - -1.8839 - 1.316 0.185 - 182 1 2 0 -0.0016 7 0 0 0 9.80E+06 1.51E+07 - - - 1.277 1 230117_WJC_METTL3_WT_vs_EV_F04.17605.17605.2 0.000589 22-Nov K.TPAILYTYSGLR[166.11].N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1363.7375 2.35 31982 17605 2 1363.741851 682.876 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3470.9 - 161326 - - - 3.1744 - 2.681 0.475 - 489.6 1 2 0 0.0043 12 0 0 0 1.30E+07 5.52E+06 - - - 5.1428 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17610.17610.2 0.00773 16-Sep R.ITELMQVLK[136.11].D "sp|P28288|ABCD3_HUMAN,tr|A0A3B3ITW3|A0A3B3ITW3_HUMAN" 2 1081.6297 0.55 31985 17610 2 1081.63196 541.8221 ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3 PE=1 SV=1 6 3471.6 - 513525 - - - 2.119 - 1.928 0.333 - 158.5 1 2 0 0.0023 9 0 0 0 4.53E+06 8.18E+06 - - - 3.3991 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.17611.17611.2 0.00063 18-Dec R.IAEFAFEYAR[166.11].N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1225.6007 2.37 31986 17611 2 1225.603307 613.8076 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3471.7 - 960889 - - - 2.132 - 2.322 0.227 - 572.3 1 2 0 0.0026 10 0 0 0 2.93E+07 1.23E+07 - - - 3.0683 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.17613.17613.2 0.142 16-Aug R.LNVLANVIR[166.11].K "sp|Q02218|ODO1_HUMAN,sp|Q9ULD0|OGDHL_HUMAN,tr|E9PFG7|E9PFG7_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|A0A0D9SFS3|A0A0D9SFS3_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 6 1020.6319 1.03 31988 17613 2 1020.632638 511.3232 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 9.75 3472 - 743557 - - - 0.6898 - 1.891 0.241 - 181.7 1 2 0 0.0007 9 0 0 0 1.43E+07 1.39E+07 - - - 2.664 1 230117_WJC_METTL3_WT_vs_EV_F04.17615.17615.2 5.92E-06 14/22 K.TPAILYTYSGLR.N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1353.7293 2.35 31990 17615 2 1353.733065 677.8719 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3472.3 - 514104 - - - 2.8167 - 2.886 0.501 - 826.2 1 2 0 0.0038 12 0 0 0 1.30E+07 5.52E+06 - - - 5.5289 0.9827 230117_WJC_METTL3_WT_vs_EV_F04.17616.17616.2 1.25 14-Jul K.TTQLLFLK[136.11].A sp|O94874|UFL1_HUMAN 1 970.5943 2.7 31991 17616 2 970.596595 486.3044 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 8.41 3472.4 - 297543 - - - 2.3975 - 1.113 0.124 - 104.6 1 2 0 0.0023 8 0 0 0 1.80E+07 6.66E+06 - - - 0.279 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.17619.17619.2 0.000612 14-Jul K.GFGFGLVK[136.11].L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 831.4734 1.2 31992 17619 2 831.472678 416.744 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3472.8 - 1.03E+06 - - - -0.8984 - 1.482 0.358 - 157.2 1 2 0 -0.0007 8 0 0 0 2.37E+08 1.98E+08 - - - 2.8714 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17621.17621.2 0.0323 20-Nov R.LLYC[160.03]TTGVLLR[166.11].R "sp|Q6P158|DHX57_HUMAN,sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 3 1317.7354 0.54 31993 17621 2 1317.73745 659.875 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 8.22 3473 - 107582 - - - 1.5451 - 1.927 0.36 - 367.7 1 2 0 0.002 11 0 0 0 7.16E+06 1.33E+07 - - - 3.4739 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.17623.17623.2 0.254 14-Sep R.LLNVWQVR[166.11].S "sp|Q15061|WDR43_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 2 1036.6057 1.16 31995 17623 2 1036.607743 519.3101 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 9.75 3473.2 - 1.13E+06 - - - 1.9516 - 1.612 0.228 - 258.5 1 2 0 0.002 8 0 0 0 5.46E+07 4.69E+07 - - - 2.1644 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.17628.17628.2 0.047 22-Jul R.LPVPESITGFAR.L "sp|Q8N5K1|CISD2_HUMAN,tr|I3L1N9|I3L1N9_HUMAN,tr|A0A2R8Y540|A0A2R8Y540_HUMAN" 3 1285.703 0.52 32000 17628 2 1285.705265 643.8588 CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1 6 3473.8 - 0 - - - 1.7329 - 1.59 0.304 - 132.5 1 2 0 0.0022 12 0 0 0 3.70E+06 7.13E+06 - - - 2.5058 1 230117_WJC_METTL3_WT_vs_EV_F04.17630.17630.2 5.27E-06 18-Oct K.LGDDIDLIVR[166.11].C sp|O15371|EIF3D_HUMAN 1 1137.6269 1.1 32001 17630 2 1137.628674 569.8207 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3474 - 2.65E+06 - - - 1.5515 - 2.568 0.509 - 322.5 1 2 0 0.0018 10 0 0 0 2.43E+08 2.22E+08 - - - 5.4325 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.17638.17638.2 0.00253 14-Aug K.LMWIPDTK.G sp|P61962|DCAF7_HUMAN 1 1002.5208 1.75 32006 17638 2 1002.523607 502.2677 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.84 3474.9 - 1.32E+06 - - - 2.761 - 1.491 0.426 - 257 1 2 0 0.0028 8 0 0 0 4.66E+07 2.66E+07 - - - 3.3913 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.17641.17641.2 0.068 18-Oct R.LPLLAVC[160.03]DYK.Q "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1190.6369 0.55 32009 17641 2 1190.642191 596.3257 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.83 3475.3 - 209691 - - - 4.417 - 2.179 0.394 - 294.2 1 2 0 0.0053 10 0 0 0 5.96E+06 1.08E+07 - - - 4.1235 1 230117_WJC_METTL3_WT_vs_EV_F04.17642.17642.2 0.000127 22-Dec K.LPVGTTATLYFR[166.11].D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1347.7426 1.23 32010 17642 2 1347.74609 674.8786 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3475.4 - 149157 - - - 2.5843 - 2.212 0.486 - 436.3 1 2 0 0.0035 12 0 0 0 1.20E+07 9.69E+06 - - - 4.7184 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.17646.17646.2 0.00025 14-Aug K.GFGFGLVK.L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 823.4592 1.2 32012 17646 2 823.45922 412.7369 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3475.9 - 6.75E+06 - - - -0.0061 - 1.469 0.431 - 208.4 1 2 0 0 8 0 0 0 2.37E+08 1.98E+08 - - - 3.3842 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.17650.17650.2 0.0455 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.18 32016 17650 2 1235.762139 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3476.4 - 315969 - - - 1.6031 - 1.673 0.246 - 185.9 1 2 0 0.002 11 0 0 0 3.94E+06 3.33E+06 - - - 2.2495 0.9556 230117_WJC_METTL3_WT_vs_EV_F04.17656.17656.2 1.36 14-May K.TILSLMTR[166.11].E sp|P53396|ACLY_HUMAN 1 943.54 1.08 32020 17656 2 943.541615 472.7773 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.41 3477 - 3.05E+06 - - - 1.7032 - 1.142 0.008 - 80.7 1 2 0 0.0016 8 0 0 0 4.26E+07 3.96E+07 - - - -0.5 0.9849 230117_WJC_METTL3_WT_vs_EV_F04.17661.17661.2 0.335 22-Jun R.LPVPESITGFAR[166.11].L "sp|Q8N5K1|CISD2_HUMAN,tr|I3L1N9|I3L1N9_HUMAN,tr|A0A2R8Y540|A0A2R8Y540_HUMAN" 3 1295.7113 1.55 32025 17661 2 1295.71327 648.8629 CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1 6 3477.6 - 256739 - - - 1.515 - 1.168 0.137 - 78.3 4 2 0 0.002 12 0 0 0 3.07E+06 1.98E+06 - - - 0.1919 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.17666.17666.2 0.19 14-Sep K.ISALALLK[136.11].M sp|Q92905|CSN5_HUMAN 1 835.5622 1.44 32028 17666 2 835.563931 418.7884 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 8.75 3478.3 - 809160 - - - 2.0238 - 2.118 0.21 - 170.2 1 2 0 0.0017 8 0 0 0 2.34E+07 1.62E+07 - - - 2.8549 1 230117_WJC_METTL3_WT_vs_EV_F04.17668.17668.2 2.12E-05 22-Dec K.LPVGTTATLYFR.D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1337.7343 1.23 32030 17668 2 1337.736147 669.8744 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3478.5 - 856576 - - - 1.353 - 2.221 0.488 - 503.2 1 2 0 0.0018 12 0 0 0 1.20E+07 9.69E+06 - - - 4.7444 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.17669.17669.2 0.105 20-Oct R.ELLIIGGVAAR.D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1110.6761 1.19 32031 17669 2 1110.679142 556.3453 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3478.6 - 800777 - - - 2.7443 - 2.102 0.264 - 244.9 1 2 0 0.003 11 0 0 0 2.72E+08 2.29E+08 - - - 2.9996 0.9913 230117_WJC_METTL3_WT_vs_EV_F04.17670.17670.2 4.03 12-Jun K.GVIFYLR.D "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 9 866.5014 3.7 32032 17670 2 866.5024 434.258 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 8.75 3478.7 - 739808 - - - 1.1264 - 1.242 0.115 - 121.4 1 2 0 0.001 7 0 0 0 4.33E+07 1.17E+07 - - - 0.5768 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.17676.17676.2 0.168 12-Aug K.FIGELFK.L "sp|O43432|IF4G3_HUMAN,sp|Q04637|IF4G1_HUMAN,tr|A0A804HJV5|A0A804HJV5_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|A0A0U1RQK7|A0A0U1RQK7_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|A0A0A0MSA7|A0A0A0MSA7_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 11 852.4745 0.31 32036 17676 2 852.476473 427.2445 Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2 6 3479.5 - 1.85E+06 - - - 2.2663 - 1.235 0.2 - 192.8 1 2 0 0.0019 7 0 0 0 6.46E+07 2.06E+08 - - - 1.1864 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17677.17677.2 0.00201 16-Sep R.LIDFLESGK.T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1020.5492 1.37 32037 17677 2 1020.551257 511.2819 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3479.6 - 1.76E+06 - - - 2.0528 - 1.839 0.37 - 199.7 1 2 0 0.0021 9 0 0 0 9.83E+07 7.15E+07 - - - 3.5357 0.959 230117_WJC_METTL3_WT_vs_EV_F04.17678.17678.2 0.545 12-Jul K.FIGELFK[136.11].L "sp|O43432|IF4G3_HUMAN,sp|Q04637|IF4G1_HUMAN,tr|A0A804HJV5|A0A804HJV5_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|A0A0U1RQK7|A0A0U1RQK7_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|A0A0A0MSA7|A0A0A0MSA7_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 11 860.4887 1.36 32038 17678 2 860.49371 431.2516 Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2 6 3479.7 - 1.44E+06 - - - 5.7746 - 1.329 0.175 - 128.3 1 2 0 0.005 7 0 0 0 4.72E+07 3.47E+07 - - - 1.2332 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.17679.17679.2 0.0239 20-Nov R.ELLIIGGVAAR[166.11].D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1120.6844 1.19 32039 17679 2 1120.687625 561.3495 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3479.8 - 1.40E+06 - - - 2.9098 - 1.869 0.3 - 386.1 1 2 0 0.0033 11 0 0 0 2.72E+08 2.29E+08 - - - 2.9476 0.8712 230117_WJC_METTL3_WT_vs_EV_F04.17682.17682.2 2.72 12-May K.LMVPLLK.F "sp|O00410|IPO5_HUMAN,sp|O60518|RNBP6_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 3 812.5194 1.72 32042 17682 2 812.522191 407.267 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 8.75 3480.1 - 441787 - - - 3.4571 - 1.067 0.028 - 81.2 2 2 0 0.0028 7 0 0 0 1.41E+07 8.18E+06 - - - -0.6821 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.17685.17685.2 0.834 16-Aug K.IAFAITAIK[136.11].G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 954.5994 1.18 32044 17685 2 954.601482 478.307 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3480.6 - 1.09E+06 - - - 2.2292 - 1.798 0.188 - 115.1 1 2 0 0.0021 9 0 0 0 4.69E+09 3.97E+09 - - - 2.1262 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.17688.17688.2 0.134 16-May R.AVDVGAFLR[166.11].D "sp|Q96BT3|CENPT_HUMAN,tr|H3BUW2|H3BUW2_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 3 956.5319 0.97 32046 17688 2 956.533301 479.2732 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 5.88 3480.8 - 738034 - - - 1.4793 - 1.509 0.121 - 53.2 1 2 0 0.0014 9 0 0 0 2.45E+07 2.53E+07 - - - 1.1246 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17690.17690.2 0.00832 20-Nov K.SEIEYYAMLAK[136.11].T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1324.6464 0.89 32048 17690 2 1324.650829 663.3305 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3481 - 435689 - - - 3.3133 - 2.288 0.436 - 431.7 1 2 0 0.0044 11 0 0 0 6.46E+06 7.23E+06 - - - 4.499 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.17691.17691.2 0.00454 18-Sep K.WSEALVLYDR[166.11].V sp|Q9UHB9|SRP68_HUMAN 1 1260.6378 1.72 32049 17691 2 1260.637234 631.3262 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.37 3481.1 - 429587 - - - -0.4553 - 1.932 0.392 - 320.7 1 2 0 -0.0006 10 0 0 0 6.16E+06 3.57E+06 - - - 3.7744 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.17696.17696.2 0.0691 16-Nov R.LAVLPYELR.F "sp|Q9ULX3|NOB1_HUMAN,tr|H3BUR4|H3BUR4_HUMAN" 2 1072.6281 1.21 32052 17696 2 1072.630792 537.3213 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 6 3481.8 - 1.49E+06 - - - 2.5274 - 2.211 0.22 - 621.5 1 2 0 0.0027 9 0 0 0 9.37E+07 7.75E+07 - - - 2.9605 1 230117_WJC_METTL3_WT_vs_EV_F04.17699.17699.2 9.60E-07 20-Oct K.SEIEYYAMLAK.T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1316.6322 0.89 32055 17699 2 1316.632406 659.3234 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3482.2 - 254009 - - - 0.1261 - 2.206 0.503 - 326.8 1 2 0 0.0002 11 0 0 0 6.46E+06 7.23E+06 - - - 4.8964 1 230117_WJC_METTL3_WT_vs_EV_F04.17703.17703.2 3.10E-10 26-Dec K.NVGLDIEAEVPAVK.D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1452.7824 999 32059 17703 2 1452.790586 727.3985 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 3482.7 - 142286 - - - 5.6278 - 2.486 0.579 - 407.4 1 2 0 0.0082 14 0 0 0 2.71E+06 0.00E+00 - - - 5.6002 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.17707.17707.2 1.14 14-Sep K.IYQVLDFR.L "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1052.5655 1.3 32061 17707 2 1052.56789 527.29 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 5.84 3483.3 - 1.12E+06 - - - 2.2887 - 1.898 0.212 - 313.1 1 2 0 0.0024 8 0 0 0 2.76E+07 2.12E+07 - - - 2.5387 0.9867 230117_WJC_METTL3_WT_vs_EV_F04.17711.17711.2 0.00175 18-Aug R.AVAGWEEVLR.W "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1128.5928 0.9 32065 17711 2 1128.588914 565.3037 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 4.53 3483.8 - 141834 - - - -3.406 - 1.718 0.237 - 138.2 1 2 0 -0.0038 10 0 0 0 1.84E+06 2.04E+06 - - - 2.3008 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.17715.17715.2 0.281 14-Jul R.GLFIIDDK.G "sp|Q06830|PRDX1_HUMAN,sp|Q13162|PRDX4_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|H7C3T4|H7C3T4_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 5 919.5015 2.16 32068 17715 2 919.504177 460.758 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.21 3484.3 - 8.89E+06 - - - 2.9288 - 1.707 0.278 - 198.9 1 2 0 0.0027 8 0 0 0 1.50E+09 6.93E+08 - - - 2.7062 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17717.17717.2 0.0168 16-Aug R.AVDVGAFLR.D "sp|Q96BT3|CENPT_HUMAN,tr|H3BUW2|H3BUW2_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 3 946.5236 0.97 32069 17717 2 946.525038 474.2691 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 5.88 3484.5 - 901641 - - - 1.5023 - 1.608 0.35 - 214.5 1 2 0 0.0014 9 0 0 0 2.45E+07 2.54E+07 - - - 2.9998 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17718.17718.2 0.0569 14-Sep K.IYQVLDFR[166.11].L "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1062.5738 1.3 32070 17718 2 1062.575851 532.2942 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 5.84 3484.6 - 1.27E+06 - - - 1.9763 - 1.948 0.269 - 299.8 1 2 0 0.0021 8 0 0 0 2.78E+07 2.15E+07 - - - 3.0382 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.17720.17720.2 8.20E-05 16-Sep K.FPTLWSGAR[166.11].S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1043.5428 1.01 32072 17720 2 1043.544503 522.7787 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 9.75 3484.7 - 1.28E+06 - - - 1.6463 - 2.092 0.394 - 359.6 1 2 0 0.0017 9 0 0 0 3.61E+07 3.56E+07 - - - 4.086 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.17721.17721.2 0.0277 14-Jul R.GIFPVLC[160.03]K[136.11].D "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 940.5296 2.01 32073 17721 2 940.53229 471.2721 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 8.22 3484.8 - 534748 - - - 2.9026 - 1.646 0.295 - 161.2 1 2 0 0.0027 8 0 0 0 4.42E+07 2.20E+07 - - - 2.722 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.17728.17728.2 0.0159 16-Jul K.VNIIPIIAK.A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 979.643 1.17 32078 17728 2 979.645379 490.8288 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3485.8 - 313491 - - - 2.4254 - 1.353 0.347 - 167.6 1 2 0 0.0024 9 0 0 0 3.98E+07 3.42E+07 - - - 2.4778 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.17729.17729.2 0.0254 16-Aug K.VNIIPIIAK[136.11].A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 987.6572 1.17 32079 17729 2 987.660689 494.8359 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3485.9 - 439818 - - - 3.5296 - 1.494 0.323 - 213.5 1 2 0 0.0035 9 0 0 0 3.98E+07 3.42E+07 - - - 2.587 0.996 230117_WJC_METTL3_WT_vs_EV_F04.17740.17740.2 0.521 12-Jun R.ISPWLLR[166.11].V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 893.5362 0.34 32088 17740 2 893.538717 447.7754 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3487.2 - 1.25E+06 - - - 2.7688 - 1.453 0.177 - 135.3 1 2 0 0.0025 7 0 0 0 3.16E+07 9.39E+07 - - - 1.5314 1 230117_WJC_METTL3_WT_vs_EV_F04.17743.17743.2 0.00352 13/20 R.YIVQVSPLGIR.L sp|Q10570|CPSF1_HUMAN 1 1243.7289 1.35 32091 17743 2 1243.733031 622.8717 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3487.6 - 663282 - - - 3.3552 - 2.517 0.487 - 676.5 1 2 0 0.0042 11 0 0 0 3.38E+07 2.51E+07 - - - 5.1338 0.9607 230117_WJC_METTL3_WT_vs_EV_F04.17744.17744.2 9.54 14-Sep S.PLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 906.5526 1.2 32092 17744 2 906.553323 454.2836 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 10.18 3487.7 - 577567 - - - 0.7744 - 1.964 0.299 - 327.8 1 1 0 0.0007 8 0 0 0 5.42E+07 4.51E+07 - - - 3.2849 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.17747.17747.2 0.0687 14-Jul R.DILIDPIR[166.11].V "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 963.5629 1.76 32095 17747 2 963.563218 482.7887 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3488 - 303275 - - - 0.3798 - 1.38 0.229 - 176.7 1 2 0 0.0004 8 0 0 0 3.05E+07 1.73E+07 - - - 1.7037 1 230117_WJC_METTL3_WT_vs_EV_F04.17748.17748.2 1.89E-09 14/30 R.VINEPTAAALAYGLDK.S "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1644.8723 76.85 32096 17748 2 1644.876794 823.4434 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3488.2 - 250488 - - - 2.74 - 2.894 0.618 - 564.5 1 2 0 0.0045 16 0 0 0 8.97E+06 1.17E+05 - - - 6.2167 0.998 230117_WJC_METTL3_WT_vs_EV_F04.17754.17754.2 0.0139 14-Jul K.WLTLEVC[160.03]R.E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1075.5485 1.62 32100 17754 2 1075.552038 538.7815 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3488.9 - 600658 - - - 3.335 - 1.469 0.317 - 230.8 1 2 0 0.0036 8 0 0 0 8.42E+07 5.19E+07 - - - 2.5411 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17756.17756.2 0.000584 16-Sep K.FPTLWSGAR.S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1033.5345 1.13 32102 17756 2 1033.535757 517.7745 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 9.75 3489 - 1.15E+06 - - - 1.2017 - 1.802 0.304 - 281.6 1 2 0 0.0012 9 0 0 0 1.01E+08 8.99E+07 - - - 2.9897 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.17758.17758.2 0.00117 22-Sep R.VFIGNLNTALVK[136.11].K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1295.7693 0.63 32104 17758 2 1295.765828 648.8919 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3489.3 - 0 - - - -2.6587 - 1.632 0.452 - 203 1 2 0 -0.0034 12 0 0 0 7.44E+07 1.17E+08 - - - 3.6672 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.17763.17763.2 0.0247 12-Aug R.ISPWLLR.V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 883.528 0.34 32107 17763 2 883.530256 442.7713 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3490 - 1.07E+06 - - - 2.584 - 1.553 0.232 - 248.4 1 2 0 0.0023 7 0 0 0 3.20E+07 9.42E+07 - - - 2.1486 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.17764.17764.2 0.404 14-Jul R.DILIDPIR.V "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 953.5546 1.74 32108 17764 2 953.556932 477.7846 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3490 - 533026 - - - 2.4645 - 1.485 0.207 - 195.6 1 2 0 0.0024 8 0 0 0 3.02E+07 1.73E+07 - - - 1.7617 1 230117_WJC_METTL3_WT_vs_EV_F04.17767.17767.2 1.23E-05 14/20 K.LASDAGIFFTR.A "sp|Q9NR46|SHLB2_HUMAN,tr|G5E9J1|G5E9J1_HUMAN,tr|F8WFB9|F8WFB9_HUMAN,tr|B7ZC39|B7ZC39_HUMAN,tr|B7ZC38|B7ZC38_HUMAN" 5 1196.619 4.01 32111 17767 2 1196.622119 599.3168 Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2 PE=1 SV=1 5.84 3490.3 - 696411 - - - 2.6291 - 2.77 0.429 - 604.3 1 2 0 0.0031 11 0 0 0 1.33E+07 3.31E+06 - - - 4.9648 1 230117_WJC_METTL3_WT_vs_EV_F04.17773.17773.2 3.32E-05 20-Nov R.IVLLDSSLEYK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1278.7071 11.27 32115 17773 2 1278.707561 640.3608 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3491.1 - 1.15E+06 - - - 0.3457 - 2.352 0.513 - 358.5 1 2 0 0.0004 11 0 0 0 1.74E+09 1.55E+08 - - - 5.1436 1 230117_WJC_METTL3_WT_vs_EV_F04.17774.17774.2 2.14E-05 22-Sep R.VFIGNLNTALVK.K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1287.7551 0.63 32116 17774 2 1287.757699 644.8848 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3491.1 - 655024 - - - 2.0392 - 1.926 0.54 - 201.1 1 2 0 0.0026 12 0 0 0 7.44E+07 1.17E+08 - - - 4.7532 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17785.17785.2 0.00194 16-Aug R.FLVQLDDYR.F "sp|Q9HAD4|WDR41_HUMAN,tr|D6RE66|D6RE66_HUMAN,tr|B4DK73|B4DK73_HUMAN,tr|D6RH33|D6RH33_HUMAN,tr|D6RA22|D6RA22_HUMAN,tr|B4DHS8|B4DHS8_HUMAN,tr|D6R9E7|D6R9E7_HUMAN,tr|H0YAA3|H0YAA3_HUMAN,tr|D6RBY6|D6RBY6_HUMAN,tr|H0YAI6|H0YAI6_HUMAN,tr|D6RB94|D6RB94_HUMAN" 11 1167.5924 1.76 32125 17785 2 1167.593599 584.8035 WD repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=WDR41 PE=1 SV=3 4.21 3492.5 - 936233 - - - 1.0063 - 1.823 0.306 - 263.4 1 2 0 0.0012 9 0 0 0 9.59E+06 5.44E+06 - - - 3.038 0.9715 230117_WJC_METTL3_WT_vs_EV_F04.17786.17786.2 0.846 12-Jun R.YLNFFTK[136.11].A sp|P12004|PCNA_HUMAN 1 939.4946 1.29 32126 17786 2 939.494774 470.7546 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3492.6 - 830029 - - - 0.2342 - 1.038 0.106 - 100.7 1 2 0 0.0002 7 0 0 0 6.96E+07 5.38E+07 - - - -0.058 0.9944 230117_WJC_METTL3_WT_vs_EV_F04.17787.17787.2 0.155 12-Jul R.YLNFFTK.A sp|P12004|PCNA_HUMAN 1 931.4804 1.29 32127 17787 2 931.481833 466.7475 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3492.7 - 826905 - - - 1.5878 - 1.24 0.16 - 140.6 1 2 0 0.0015 7 0 0 0 6.95E+07 5.38E+07 - - - 0.9039 1 230117_WJC_METTL3_WT_vs_EV_F04.17788.17788.2 1.11E-05 20-Dec K.FATEAAITILR[166.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1214.6898 11.74 32128 17788 2 1214.694948 608.3522 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3492.8 - 741312 - - - 4.2027 - 2.187 0.492 - 575.3 1 2 0 0.0051 11 0 0 0 1.36E+09 1.16E+08 - - - 4.7902 0.9256 230117_WJC_METTL3_WT_vs_EV_F04.17789.17789.2 0.107 Jun-32 R.ASSGGGAGGAAGYAPVK.Y sp|P25067|CO8A2_HUMAN 1 1376.6684 2.71 32129 17789 2 1376.664651 689.3415 Collagen alpha-2(VIII) chain OS=Homo sapiens OX=9606 GN=COL8A2 PE=1 SV=2 8.63 3493 - 505510 - - - -2.7537 - 1.288 0.15 - 49.8 4 2 0 -0.0038 17 0 0 0 2.57E+07 9.47E+06 - - - 0.501 1 230117_WJC_METTL3_WT_vs_EV_F04.17799.17799.2 7.31E-05 20-Nov K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 11.74 32137 17799 2 1204.682128 603.3481 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3494.2 - 1.04E+07 - - - 0.4607 - 2.402 0.535 - 469.8 1 2 0 0.0006 11 0 0 0 1.36E+09 1.16E+08 - - - 5.3629 1 230117_WJC_METTL3_WT_vs_EV_F04.17800.17800.2 0.000807 18-Nov K.IIQLLDDYPK[136.11].C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1224.6845 1.03 32138 17800 2 1224.68483 613.3495 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3494.2 - 1.91E+06 - - - 0.2368 - 2.4 0.445 - 395.7 1 2 0 0.0003 10 0 0 0 4.16E+08 4.03E+08 - - - 4.7714 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17801.17801.2 1.21 14-Oct R.IVEVLLIK.D "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 925.6212 1.16 32139 17801 2 925.623221 463.8179 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6 3494.4 - 400650 - - - 2.178 - 2.033 0.364 - 224.1 1 2 0 0.002 8 0 0 0 2.01E+07 1.73E+07 - - - 3.8687 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.17807.17807.3 0.00495 Dec-40 K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 12.95 32143 17807 3 1204.681796 402.5678 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3495.1 - 1.23E+06 - - - 0.1851 - 2.005 0.368 - 153.1 1 2 0 0.0002 11 0 0 0 2.76E+07 2.13E+06 - - - 4.619 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.17813.17813.2 0.228 16-Oct K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 0.82 32148 17813 2 993.586378 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 3495.9 - 792488 - - - 1.7392 - 2.194 0.217 - 415.4 1 2 0 0.0017 9 0 0 0 2.66E+07 3.25E+07 - - - 2.9164 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.17830.17830.2 0.153 18-Jul R.FGFGFGNGMK[136.11].Q "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 8 1068.4942 0.62 32160 17830 2 1068.496207 535.2544 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 8.75 3497.8 - 616107 - - - 1.8437 - 1.102 0.297 - 44.5 1 2 0 0.002 10 0 0 0 5.42E+06 8.75E+06 - - - 1.5051 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.17832.17832.2 0.00252 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 1254.1 32161 17832 2 1006.571559 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3498.1 - 3.33E+06 - - - 1.6502 - 1.892 0.444 - 262.8 1 2 0 0.0017 9 0 0 0 9.21E+08 7.34E+05 - - - 4.1646 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.17834.17834.2 2.21 12-Aug R.WLITLNK.Q "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 886.5276 1.08 32162 17834 2 886.528061 444.2711 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 8.75 3498.3 - 8.11E+06 - - - 0.476 - 1.612 0.109 - 353.4 1 2 0 0.0004 7 0 0 0 1.84E+08 1.71E+08 - - - 1.3588 0.9889 230117_WJC_METTL3_WT_vs_EV_F04.17836.17836.2 0.111 16-Aug R.GAGWLFGAK.V sp|O00743|PPP6_HUMAN 1 905.4759 2.36 32164 17836 2 905.475933 453.7452 Serine\threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1 8.75 3498.4 - 1.81E+06 - - - -0.0055 - 1.083 0.19 - 126.8 1 2 0 0 9 0 0 0 1.82E+07 7.72E+06 - - - 0.675 1 230117_WJC_METTL3_WT_vs_EV_F04.17846.17846.2 8.82E-08 18-Nov R.EC[160.03]LNLWGYER.V sp|Q86U44|MTA70_HUMAN 1 1338.6027 32.16 32172 17846 2 1338.604374 670.3086 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3499.7 - 847734 - - - 1.2722 - 2.111 0.565 - 671.2 1 2 0 0.0017 10 0 0 0 4.89E+07 1.52E+06 - - - 5.2991 0.9717 230117_WJC_METTL3_WT_vs_EV_F04.17848.17848.2 0.119 18-Aug K.SFIMSSTLIR[166.11].H sp|Q9UEG4|ZN629_HUMAN 1 1163.6248 1.03 32174 17848 2 1163.618931 582.8197 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.47 3500 - 425481 - - - -5.0437 - 1.6 0.301 - 196.7 1 2 0 -0.0059 10 0 0 0 6.09E+06 5.94E+06 - - - 2.5743 0.9916 230117_WJC_METTL3_WT_vs_EV_F04.17857.17857.2 0.0321 18-Aug K.SFIMSSTLIR.H sp|Q9UEG4|ZN629_HUMAN 1 1153.6165 1.03 32182 17857 2 1153.620462 577.8155 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.47 3501.1 - 658306 - - - 3.4084 - 1.417 0.184 - 162.4 2 2 0 0.0039 10 0 0 0 6.09E+06 5.94E+06 - - - 1.2372 0.9929 230117_WJC_METTL3_WT_vs_EV_F04.17858.17858.2 0.00733 16-Aug K.NFDMVIVYK[136.11].D sp|Q9Y5B9|SP16H_HUMAN 1 1135.5827 1.08 32183 17858 2 1135.580257 568.7986 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.83 3501.2 - 648147 - - - -2.1663 - 1.382 0.295 - 108 1 2 0 -0.0025 9 0 0 0 4.87E+06 4.53E+06 - - - 2.1551 0.9882 230117_WJC_METTL3_WT_vs_EV_F04.17860.17860.2 0.403 14-Jun R.FLLETVVR.V "sp|Q5R372|RBG1L_HUMAN,tr|A0A0U1RRM5|A0A0U1RRM5_HUMAN,tr|A0A0C4DG54|A0A0C4DG54_HUMAN,tr|A0A804HKD7|A0A804HKD7_HUMAN" 4 975.5753 0.79 32185 17860 2 975.575798 488.7949 Rab GTPase-activating protein 1-like OS=Homo sapiens OX=9606 GN=RABGAP1L PE=1 SV=1 6 3501.5 - 271883 - - - 0.493 - 1.455 0.058 - 92.4 2 2 0 0.0005 8 0 0 0 1.87E+06 2.37E+06 - - - 0.4658 0.9925 230117_WJC_METTL3_WT_vs_EV_F04.17862.17862.2 0.316 12-Jun R.LILMDLK.G "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 844.5092 2.69 32186 17862 2 844.509932 423.2619 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.84 3501.7 - 627633 - - - 0.8526 - 1.261 0.127 - 103.8 1 2 0 0.0007 7 0 0 0 2.08E+07 7.76E+06 - - - 0.7136 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.17865.17865.2 0.0102 14-Aug R.NILIVLTK[136.11].L "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN,tr|H0Y815|H0Y815_HUMAN" 3 920.615 0.74 32188 17865 2 920.61577 461.3148 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 8.75 3502.1 - 575650 - - - 0.8321 - 1.36 0.361 - 155.4 1 2 0 0.0008 8 0 0 0 5.58E+06 7.51E+06 - - - 2.6345 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.17867.17867.2 0.00265 16-Aug K.AENPYLFLR.G "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN" 2 1121.5869 1.34 32190 17867 2 1121.584215 561.8007 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 6.05 3502.3 - 510779 - - - -2.4341 - 1.602 0.434 - 208 1 2 0 -0.0027 9 0 0 0 8.41E+06 6.28E+06 - - - 3.609 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.17874.17874.2 0.000277 18-Oct R.FLLADNLYC[160.03]K.A sp|P61758|PFD3_HUMAN 1 1255.6271 3.29 32195 17874 2 1255.62833 628.8208 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 5.83 3503.2 - 2.26E+06 - - - 0.9836 - 2.097 0.462 - 282 1 2 0 0.0012 10 0 0 0 2.32E+07 7.07E+06 - - - 4.5199 1 230117_WJC_METTL3_WT_vs_EV_F04.17881.17881.2 2.13E-05 16-Sep K.NFDMVIVYK.D sp|Q9Y5B9|SP16H_HUMAN 1 1127.5685 1.08 32202 17881 2 1127.571945 564.7915 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.83 3504.1 - 601486 - - - 3.0402 - 1.759 0.546 - 269 1 2 0 0.0034 9 0 0 0 4.87E+06 4.53E+06 - - - 4.7065 0.9877 230117_WJC_METTL3_WT_vs_EV_F04.17882.17882.2 0.203 14-Aug K.IEISELNR.V "sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 2 972.524 1.54 32203 17882 2 972.527335 487.2693 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 3504.3 - 406715 - - - 3.4189 - 1.6 0.066 - 187.4 1 2 0 0.0033 8 0 0 0 4.00E+06 2.59E+06 - - - 0.9449 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.17883.17883.2 0.00965 14-Sep R.LSVLLGLK.K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 841.5637 2.23 32204 17883 2 841.566101 421.7891 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3504.4 - 397056 - - - 2.8649 - 2.025 0.346 - 219.2 1 2 0 0.0024 8 0 0 0 3.94E+06 1.77E+06 - - - 3.7238 0.999 230117_WJC_METTL3_WT_vs_EV_F04.17885.17885.2 0.00263 14-Oct R.LSVLLGLK[136.11].K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 849.5779 2.23 32206 17885 2 849.580647 425.7962 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3504.7 - 221986 - - - 3.2451 - 1.94 0.314 - 238.6 1 2 0 0.0028 8 0 0 0 3.94E+06 1.77E+06 - - - 3.358 1 230117_WJC_METTL3_WT_vs_EV_F04.17886.17886.2 1.29E-11 14/30 K.VLAQNSGFDLQETLVK.L sp|P40227|TCPZ_HUMAN 1 1760.9309 999 32207 17886 2 1760.935521 881.4727 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3504.8 - 201098 - - - 2.6441 - 3.055 0.655 - 495.2 1 2 0 0.0047 16 0 0 0 1.48E+06 0.00E+00 - - - 6.623 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.17887.17887.2 7.64E-05 20-Dec K.LALDMEINAYR.K sp|Q03252|LMNB2_HUMAN 1 1307.6544 0.49 32208 17887 2 1307.659377 654.8345 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.37 3504.9 - 194670 - - - 3.8275 - 2.455 0.317 - 699.7 1 2 0 0.005 11 0 0 0 1.26E+06 2.55E+06 - - - 3.8104 1 230117_WJC_METTL3_WT_vs_EV_F04.17888.17888.2 3.23E-05 14/24 K.VLATTFDPYLGGR.N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1408.7351 13.19 32209 17888 2 1408.741671 705.3748 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3505 - 173746 - - - 4.6893 - 2.661 0.579 - 447 1 2 0 0.0066 13 0 0 0 2.77E+07 2.10E+06 - - - 5.8273 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.17891.17891.2 0.0701 20-Jul R.IVLLDSSLEYK[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1286.7213 11.27 32211 17891 2 1286.724045 644.3679 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3505.4 - 204933 - - - 2.1186 - 1.542 0.262 - 110.5 1 2 0 0.0027 11 0 0 0 1.74E+09 1.55E+08 - - - 2.1469 0.9969 230117_WJC_METTL3_WT_vs_EV_F04.17892.17892.2 0.106 14-Aug R.LDTIFFAK.Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 953.5222 2.43 32212 17892 2 953.525651 477.7684 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3505.5 - 2.15E+06 - - - 3.5993 - 1.856 0.179 - 184.7 1 2 0 0.0034 8 0 0 0 8.75E+07 3.60E+07 - - - 2.2272 1 230117_WJC_METTL3_WT_vs_EV_F04.17894.17894.2 0.000135 18-Nov K.VEDAMLMFDK.T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|A0A6Q8PHP1|A0A6Q8PHP1_HUMAN" 6 1197.541 44.12 32214 17894 2 1197.542753 599.7778 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.03 3505.7 - 1.62E+06 - - - 1.4789 - 2.125 0.502 - 365.5 1 2 0 0.0018 10 0 0 0 1.23E+07 2.79E+05 - - - 4.8522 1 230117_WJC_METTL3_WT_vs_EV_F04.17895.17895.2 4.13E-08 13/18 K.VDDAMLMFDK.T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1183.5253 1.37 32215 17895 2 1183.531069 592.7699 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 3.93 3505.8 - 1.31E+06 - - - 4.8474 - 2.377 0.645 - 647.5 1 2 0 0.0057 10 0 0 0 1.96E+07 1.43E+07 - - - 6.22 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.17897.17897.2 0.0375 14-Aug R.LDTIFFAK[136.11].Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 961.5364 2.49 32217 17897 2 961.539784 481.7755 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3506 - 1.11E+06 - - - 3.4996 - 1.862 0.191 - 186.9 1 2 0 0.0034 8 0 0 0 8.41E+07 3.37E+07 - - - 2.3255 0.9952 230117_WJC_METTL3_WT_vs_EV_F04.17898.17898.2 0.0152 14-Sep R.ADLIAYLK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 905.5222 1.35 32218 17898 2 905.525756 453.7684 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 5.88 3506.1 - 746710 - - - 3.906 - 1.557 0.222 - 219.4 1 2 0 0.0035 8 0 0 0 1.26E+07 9.35E+06 - - - 2.0149 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.17902.17902.2 0.00127 20-Aug K.LPVVISQC[160.03]GEM.- "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1231.5941 - 32222 17902 2 1231.598261 616.8043 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4 3506.6 - 565386 - - - 3.3948 - 1.38 0.425 - 178.8 1 2 0 0.0042 11 0 0 0 - - - - - 3.05 0.981 230117_WJC_METTL3_WT_vs_EV_F04.17909.17909.2 0.477 14-May R.VLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 815.4753 0.17 32229 17909 2 815.477521 408.7449 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 3507.5 - 252687 - - - 2.7616 - 0.856 0.24 - 63.3 1 2 0 0.0023 8 0 0 0 2.82E+06 1.68E+07 - - - 0.344 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.17912.17912.2 0.0448 20-Nov R.YGLIGLNGIGK[136.11].S "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1111.6481 2.4 32231 17912 2 1111.651321 556.8313 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.59 3507.9 - 1.21E+06 - - - 2.902 - 1.729 0.252 - 176.9 1 2 0 0.0032 11 0 0 0 3.91E+07 1.63E+07 - - - 2.3825 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.17913.17913.2 1.79E-05 20-Oct R.AVVPSYIPLVK[136.11].K sp|P36551|HEM6_HUMAN 1 1192.7311 1.13 32232 17913 2 1192.734912 597.3728 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3508 - 5.37E+06 - - - 3.1994 - 2.028 0.36 - 340.8 1 2 0 0.0038 11 0 0 0 1.14E+08 1.01E+08 - - - 3.6115 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.17914.17914.2 2.88E-05 20-Sep R.AVVPSYIPLVK.K sp|P36551|HEM6_HUMAN 1 1184.7169 1.13 32233 17914 2 1184.721082 593.3657 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3508 - 4.99E+06 - - - 3.5333 - 1.666 0.392 - 302.7 1 2 0 0.0042 11 0 0 0 1.14E+08 1.01E+08 - - - 3.3158 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.17916.17916.2 0.00219 16-Aug R.FLSPEFIPR.R "sp|P49406|RM19_HUMAN,tr|A0A0A0MRF4|A0A0A0MRF4_HUMAN" 2 1104.5968 0.87 32235 17916 2 1104.601124 553.3057 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 6 3508.1 - 4.02E+06 - - - 3.9318 - 1.637 0.402 - 204.7 1 2 0 0.0043 9 0 0 0 1.32E+07 1.52E+07 - - - 3.4347 0.9969 230117_WJC_METTL3_WT_vs_EV_F04.17918.17918.2 0.189 14-Aug R.ADLIAYLK[136.11].K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 913.5364 1.34 32237 17918 2 913.539641 457.7755 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 5.88 3508.4 - 2.00E+06 - - - 3.527 - 1.81 0.182 - 194.8 1 2 0 0.0032 8 0 0 0 1.26E+07 9.46E+06 - - - 2.1737 0.9942 230117_WJC_METTL3_WT_vs_EV_F04.17919.17919.2 0.00408 16-Sep K.IIGNLLYYR.Y "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1123.639 1.23 32238 17919 2 1123.645724 562.8268 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.59 3508.5 - 1.59E+06 - - - 6.0019 - 2.076 0.316 - 177.1 1 2 0 0.0067 9 0 0 0 2.39E+07 1.94E+07 - - - 3.4861 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.17921.17921.2 0.0179 18-Sep R.LITTQQWLIK[136.11].L sp|P00846|ATP6_HUMAN 1 1250.7478 1.13 32240 17921 2 1250.751696 626.3812 ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1 8.75 3508.8 - 984287 - - - 3.1077 - 1.906 0.337 - 205.9 1 2 0 0.0039 10 0 0 0 4.49E+06 3.99E+06 - - - 3.3293 0.8619 230117_WJC_METTL3_WT_vs_EV_F04.17922.17922.2 6.58 22-Jun R.TFLSSPMEVGK[136.11]K.L "sp|Q9Y4G8|RPGF2_HUMAN,tr|A0A2R8Y661|A0A2R8Y661_HUMAN,tr|A0A2R8YGD3|A0A2R8YGD3_HUMAN" 3 1330.7046 - 32241 17922 2 1330.709105 666.3596 Rap guanine nucleotide exchange factor 2 OS=Homo sapiens OX=9606 GN=RAPGEF2 PE=1 SV=1 8.26 3508.9 - 971353 - - - 3.3681 - 1.032 0.044 - 72.4 3 2 0 0.0045 12 0 0 0 - - - - - -0.7657 1 230117_WJC_METTL3_WT_vs_EV_F04.17923.17923.2 0.000996 18-Dec R.LITTQQWLIK.L sp|P00846|ATP6_HUMAN 1 1242.7336 1.13 32242 17923 2 1242.73784 622.3741 ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1 8.75 3509 - 859824 - - - 3.4046 - 2.164 0.502 - 330.8 1 2 0 0.0042 10 0 0 0 4.49E+06 3.99E+06 - - - 4.9022 1 230117_WJC_METTL3_WT_vs_EV_F04.17924.17924.2 8.00E-06 24-Dec K.VLATTFDPYLGGR[166.11].N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1418.7433 13.19 32243 17924 2 1418.747388 710.3789 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3509.1 - 593563 - - - 2.8568 - 2.42 0.512 - 351.3 1 2 0 0.0041 13 0 0 0 2.77E+07 2.10E+06 - - - 5.0896 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.17928.17928.2 0.243 28-Oct R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 5.51 32247 17928 2 1484.91202 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3509.7 - 516764 - - - 2.7847 - 2.012 0.307 - 219.4 1 2 0 0.0041 15 0 0 0 1.71E+07 3.10E+06 - - - 3.026 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.17932.17932.2 0.00639 14-Aug K.NILTEIYR.L sp|Q15907|RB11B_HUMAN 1 1020.5604 1.47 32250 17932 2 1020.564757 511.2875 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 6 3510.1 - 1.60E+06 - - - 4.2741 - 1.675 0.375 - 245.4 1 2 0 0.0044 8 0 0 0 2.28E+07 1.55E+07 - - - 3.365 1 230117_WJC_METTL3_WT_vs_EV_F04.17934.17934.2 2.84E-07 14/18 R.IC[160.03]DDELILIK.N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1230.653 9.53 32252 17934 2 1230.656166 616.3338 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3510.3 - 6.11E+06 - - - 2.5921 - 2.868 0.421 - 529.4 1 2 0 0.0032 10 0 0 0 7.58E+08 7.95E+07 - - - 5.0905 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.17935.17935.2 0.00567 14-Aug R.GIFEPFGR.L "sp|Q14498|RBM39_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 5 921.4709 1.26 32253 17935 2 921.472709 461.7427 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 6 3510.3 - 3.04E+06 - - - 2.0153 - 1.587 0.203 - 259.3 1 2 0 0.0019 8 0 0 0 4.35E+07 3.45E+07 - - - 1.9327 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17936.17936.2 0.00707 16-Nov K.IIGNLLYYR[166.11].Y "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1133.6472 1.23 32254 17936 2 1133.650426 567.8309 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.59 3510.4 - 2.32E+06 - - - 2.8016 - 2.289 0.337 - 321.2 1 2 0 0.0032 9 0 0 0 2.39E+07 1.94E+07 - - - 3.9249 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.17938.17938.2 0.00617 20-Sep R.LLALNSLYSPK.L sp|P78527|PRKDC_HUMAN 1 1217.702 1.35 32256 17938 2 1217.70537 609.8583 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.59 3510.5 - 1.73E+06 - - - 2.7889 - 1.959 0.26 - 235 1 2 0 0.0034 11 0 0 0 4.86E+07 3.60E+07 - - - 2.7794 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.17939.17939.2 0.0884 14-Aug K.ILILQGLK.Q "sp|Q9UNX4|WDR3_HUMAN,tr|D6RCT0|D6RCT0_HUMAN" 2 896.6059 0.98 32257 17939 2 896.607726 449.3102 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 8.75 3510.6 - 1.66E+06 - - - 2.0488 - 1.762 0.101 - 184.1 1 2 0 0.0018 8 0 0 0 1.02E+07 1.03E+07 - - - 1.4948 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17940.17940.2 0.194 18-Nov K.EVLLVALGSR.Q sp|Q10570|CPSF1_HUMAN 1 1055.6339 1.61 32258 17940 2 1055.635518 528.8242 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6.1 3510.6 - 672432 - - - 1.5375 - 2.101 0.281 - 429.1 1 2 0 0.0016 10 0 0 0 1.09E+07 6.74E+06 - - - 3.1883 1 230117_WJC_METTL3_WT_vs_EV_F04.17941.17941.2 6.27E-12 17/38 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 5.94 32259 17941 2 2187.043584 1094.5262 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3510.8 - 384633 - - - 2.6145 - 3.306 0.691 - 713.2 1 2 0 0.0057 20 0 0 0 2.78E+06 4.68E+05 - - - 7.0827 1 230117_WJC_METTL3_WT_vs_EV_F04.17942.17942.3 8.22E-11 17/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 8.18 32260 17942 3 2187.037994 730.0199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3510.9 - 372472 - - - 0.0585 - 3.266 0.629 - 206.5 1 2 0 0.0001 20 0 0 0 3.66E+06 4.48E+05 - - - 8.4241 0.9851 230117_WJC_METTL3_WT_vs_EV_F04.17944.17944.3 0.000324 Nov-76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 -1 32262 17944 3 2198.052743 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3511.2 - 141901 - - - 458.1638 - 1.906 0.403 - 80.4 1 2 0 1.0066 20 0 0 0 0.00E+00 0.00E+00 - - - 4.319 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17947.17947.2 0.00464 16-Sep R.AVALYFIDK[136.11].L "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN,tr|E5RIC7|E5RIC7_HUMAN" 4 1046.5892 1.36 32264 17947 2 1046.5914 524.3019 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 5.88 3511.6 - 987875 - - - 2.1183 - 1.819 0.403 - 285.3 1 2 0 0.0022 9 0 0 0 2.30E+07 1.69E+07 - - - 3.7477 0.961 230117_WJC_METTL3_WT_vs_EV_F04.17949.17949.2 0.0017 18-Oct G.AGALQVVGLK[136.11].T sp|Q9P1Q0|VPS54_HUMAN 1 962.6004 2.12 32265 17949 2 962.601797 482.3075 Vacuolar protein sorting-associated protein 54 OS=Homo sapiens OX=9606 GN=VPS54 PE=1 SV=2 8.8 3511.8 - 3.78E+06 - - - 1.4347 - 1.806 0.339 - 212.1 1 1 0 0.0014 10 0 0 0 1.27E+08 6.02E+07 - - - 3.1944 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.17950.17950.2 1.42 14-Sep K.ILILQGLK[136.11].Q "sp|Q9UNX4|WDR3_HUMAN,tr|D6RCT0|D6RCT0_HUMAN" 2 904.6201 0.98 32266 17950 2 904.62126 453.3173 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 8.75 3512 - 796132 - - - 1.2945 - 1.601 0.111 - 192.2 1 2 0 0.0012 8 0 0 0 1.02E+07 1.03E+07 - - - 1.2799 1 230117_WJC_METTL3_WT_vs_EV_F04.17951.17951.2 2.56E-05 20-Nov K.VLTPELYAELR[166.11].A "sp|P12277|KCRB_HUMAN,tr|G3V461|G3V461_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 3 1312.7266 0.89 32267 17951 2 1312.728053 657.3706 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.53 3512.1 - 1.56E+06 - - - 1.0893 - 2.272 0.451 - 378.7 1 2 0 0.0014 11 0 0 0 4.05E+07 4.55E+07 - - - 4.5917 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.17952.17952.2 0.00074 18-Dec K.VLALLDVPDK[136.11].S sp|Q9NX62|IMPA3_HUMAN 1 1089.6525 0.99 32268 17952 2 1089.657055 545.8335 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.21 3512.2 - 1.19E+06 - - - 4.1701 - 2.288 0.187 - 501.2 1 2 0 0.0045 10 0 0 0 3.69E+07 3.74E+07 - - - 2.7311 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17953.17953.2 4.49E-06 20-Oct K.VLTPELYAELR.A "sp|P12277|KCRB_HUMAN,tr|G3V461|G3V461_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 3 1302.7184 0.89 32269 17953 2 1302.721668 652.3665 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.53 3512.4 - 1.04E+06 - - - 2.5447 - 2.277 0.32 - 383 1 2 0 0.0033 11 0 0 0 4.05E+07 4.55E+07 - - - 3.6295 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17954.17954.2 0.000335 13/22 R.IGPLSPFTNAYR.R "sp|O75486|SUPT3_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 2 1334.6983 1.8 32270 17954 2 1334.701938 668.3564 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 8.75 3512.5 - 937171 - - - 2.7362 - 2.127 0.394 - 365.4 1 2 0 0.0037 12 0 0 0 1.19E+07 6.62E+06 - - - 3.9357 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.17955.17955.3 0.0327 13/36 R.FSVLLLHGIR.F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1153.6972 2.36 32271 17955 3 1153.701425 385.573 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3512.6 - 781790 - - - 3.6933 - 2.198 0.355 - 209.5 1 2 0 0.0043 10 0 0 0 5.81E+06 2.47E+06 - - - 4.7967 0.9963 230117_WJC_METTL3_WT_vs_EV_F04.17956.17956.2 0.017 18-Oct K.EVLLVALGSR[166.11].Q sp|Q10570|CPSF1_HUMAN 1 1065.6422 1.62 32272 17956 2 1065.647204 533.8284 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6.1 3512.7 - 611872 - - - 4.7286 - 1.688 0.323 - 310 1 2 0 0.005 10 0 0 0 1.10E+07 6.80E+06 - - - 2.8865 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.17963.17963.3 1.33 Nov-36 R.FSVLLLHGIR[166.11].F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1163.7054 2.73 32279 17963 3 1163.70907 388.9091 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3513.6 - 303884 - - - 3.1245 - 2.201 0.207 - 101.1 1 2 0 0.0036 10 0 0 0 5.75E+06 2.10E+06 - - - 3.1508 0.9954 230117_WJC_METTL3_WT_vs_EV_F04.17970.17970.2 0.00189 24-Sep R.LPLLPPESPGPLR.Q "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN,tr|A0A669KAX5|A0A669KAX5_HUMAN" 6 1384.8078 6.79 32285 17970 2 1384.814383 693.4112 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 6 3514.5 - 129098 - - - 4.7277 - 1.743 0.295 - 244.9 1 2 0 0.0065 13 0 0 0 1.08E+06 1.59E+05 - - - 2.6438 0.9616 230117_WJC_METTL3_WT_vs_EV_F04.17972.17972.2 0.00346 18-Sep G.AGALQVVGLK.T sp|Q9P1Q0|VPS54_HUMAN 1 954.5862 2.15 32287 17972 2 954.587962 478.3004 Vacuolar protein sorting-associated protein 54 OS=Homo sapiens OX=9606 GN=VPS54 PE=1 SV=2 8.8 3514.7 - 1.44E+07 - - - 1.8291 - 1.85 0.344 - 209.2 1 1 0 0.0017 10 0 0 0 1.30E+08 6.03E+07 - - - 3.2984 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.17973.17973.2 0.0024 14-Aug R.LFGALLER[166.11].G sp|Q9BVI4|NOC4L_HUMAN 1 927.5417 1.07 32288 17973 2 927.543956 464.7781 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3514.7 - 6.21E+06 - - - 2.4085 - 1.974 0.226 - 202.6 1 2 0 0.0022 8 0 0 0 6.22E+07 5.82E+07 - - - 2.7606 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.17974.17974.2 0.0515 14-Aug K.IDHILDAL.- "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 908.4967 - 32289 17974 2 908.498957 455.2556 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.2 3514.8 - 1.52E+06 - - - 2.448 - 1.48 0.183 - 162.7 1 2 0 0.0022 8 0 0 0 - - - - - 1.5743 1 230117_WJC_METTL3_WT_vs_EV_F04.17975.17975.2 5.87E-07 18-Nov R.VVYIFGPPVK.E sp|P49915|GUAA_HUMAN 1 1117.6536 3.57 32290 17975 2 1117.656431 559.8341 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 8.56 3515 - 1.11E+06 - - - 2.5616 - 2.129 0.531 - 538.6 1 2 0 0.0029 10 0 0 0 1.51E+07 4.24E+06 - - - 5.0713 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.17986.17986.2 0.0508 14-Sep R.LFGALLER.G sp|Q9BVI4|NOC4L_HUMAN 1 917.5335 1.06 32299 17986 2 917.536508 459.774 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3516.4 - 8.15E+06 - - - 3.3307 - 1.814 0.209 - 230.5 1 2 0 0.0031 8 0 0 0 6.58E+07 6.19E+07 - - - 2.3798 1 230117_WJC_METTL3_WT_vs_EV_F04.17993.17993.2 6.33E-06 22-Dec R.IGPLSPFTNAYR[166.11].R "sp|O75486|SUPT3_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 2 1344.7066 1.82 32306 17993 2 1344.707382 673.3606 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 8.75 3517 - 717825 - - - 0.6143 - 2.286 0.486 - 320.1 1 2 0 0.0008 12 0 0 0 1.19E+07 6.56E+06 - - - 4.8058 0.988 230117_WJC_METTL3_WT_vs_EV_F04.17994.17994.2 3 12-Jun K.FLELLPK.D "sp|P63010|AP2B1_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 5 858.5215 1.62 32307 17994 2 858.521834 430.268 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 6 3517.1 - 674085 - - - 0.3995 - 1.249 0.118 - 119.5 2 2 0 0.0003 7 0 0 0 3.11E+07 1.91E+07 - - - 0.4825 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.17995.17995.2 0.375 22-Dec R.LLQTIAVLEAQR.S sp|Q8IYH5|ZZZ3_HUMAN 1 1353.798 4.56 32308 17995 2 1353.800262 677.9063 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 6 3517.2 - 572195 - - - 1.6709 - 2.325 0.332 - 608.8 1 2 0 0.0023 12 0 0 0 3.75E+06 8.22E+05 - - - 3.7124 1 230117_WJC_METTL3_WT_vs_EV_F04.17996.17996.2 7.59E-06 13/22 K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 999 32309 17996 2 1474.745268 738.3781 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3517.4 - 533070 - - - 2.4825 - 2.689 0.564 - 674.1 1 2 0 0.0037 12 0 0 0 4.80E+06 0.00E+00 - - - 5.8082 0.9896 230117_WJC_METTL3_WT_vs_EV_F04.18003.18003.2 0.184 14-Aug R.DVDFELIK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 985.5212 5.17 32314 18003 2 985.525037 493.7679 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3518.1 - 2.70E+06 - - - 3.9309 - 1.26 0.217 - 164.6 1 2 0 0.0039 8 0 0 0 9.14E+08 1.77E+08 - - - 1.3396 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.18005.18005.2 0.00438 14-Jun R.QMFLATWK.D sp|Q10567|AP1B1_HUMAN 1 1023.5212 0.47 32316 18005 2 1023.525065 512.7679 AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2 8.75 3518.4 - 381588 - - - 3.8026 - 1.268 0.39 - 97.7 1 2 0 0.0039 8 0 0 0 4.10E+06 8.75E+06 - - - 2.6364 1 230117_WJC_METTL3_WT_vs_EV_F04.18008.18008.2 8.11E-07 20-Oct R.FPC[160.03]VVYINEVR.V sp|Q69YN4|VIR_HUMAN 1 1394.7017 2.76 32319 18008 2 1394.704228 698.3581 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 5.99 3518.8 - 203368 - - - 1.8434 - 2.029 0.517 - 441.4 1 2 0 0.0026 11 0 0 0 3.33E+06 1.20E+06 - - - 4.7728 0.9946 230117_WJC_METTL3_WT_vs_EV_F04.18017.18017.2 6.28 12-Aug R.LLDFLQK.R "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 875.5117 1.36 32326 18017 2 875.514536 438.7631 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.84 3519.9 - 1.11E+06 - - - 3.2918 - 1.576 0.143 - 161.3 1 2 0 0.0029 7 0 0 0 8.79E+07 6.47E+07 - - - 1.5376 1 230117_WJC_METTL3_WT_vs_EV_F04.18022.18022.2 9.25E-05 22-Oct K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 7.73 32331 18022 2 1332.745295 667.3774 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3520.3 - 565875 - - - 3.8597 - 2.187 0.523 - 300.4 1 2 0 0.0051 12 0 0 0 6.28E+09 8.13E+08 - - - 4.9612 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.18023.18023.2 0.00341 16-Oct R.VVLPYLVPK.L sp|Q92616|GCN1_HUMAN 1 1026.6478 1.12 32332 18023 2 1026.651599 514.3312 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.56 3520.4 - 266369 - - - 3.7452 - 1.587 0.364 - 319.6 1 2 0 0.0038 9 0 0 0 4.60E+07 4.11E+07 - - - 3.0644 0.9906 230117_WJC_METTL3_WT_vs_EV_F04.18027.18027.2 0.453 12-Sep R.LLDFLQK[136.11].R "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 883.5259 1.36 32334 18027 2 883.528446 442.7702 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.84 3521 - 2.07E+06 - - - 2.9337 - 1.689 0.03 - 202.4 1 2 0 0.0026 7 0 0 0 8.77E+07 6.45E+07 - - - 0.9225 0.9208 230117_WJC_METTL3_WT_vs_EV_F04.18028.18028.2 1.25 14-Jun R.LYPVLLVK.Q "sp|Q7Z7F7|RM55_HUMAN,tr|X6RIW1|X6RIW1_HUMAN" 2 943.6106 1.15 32335 18028 2 943.613777 472.8126 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 8.59 3521.1 - 815000 - - - 3.3245 - 0.95 0.097 - 80.5 1 2 0 0.0031 8 0 0 0 2.61E+07 2.26E+07 - - - -0.3982 1 230117_WJC_METTL3_WT_vs_EV_F04.18029.18029.2 0.000307 13/18 R.IC[160.03]DDELILIK[136.11].N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1238.6672 9.55 32336 18029 2 1238.67214 620.3409 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3521.2 - 1.66E+06 - - - 4.0075 - 2.803 0.389 - 380 1 2 0 0.005 10 0 0 0 7.59E+08 7.95E+07 - - - 4.7896 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.18034.18034.2 9.37E-07 22-Nov K.LFVTNDAATILR[166.11].E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1342.7484 7.73 32341 18034 2 1342.753159 672.3815 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3521.9 - 284237 - - - 3.5286 - 2.144 0.451 - 325.3 1 2 0 0.0047 12 0 0 0 6.28E+09 8.13E+08 - - - 4.3773 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.18042.18042.2 0.0126 14-Sep K.LDYILGLK[136.11].L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 941.5677 0.8 32347 18042 2 941.570037 471.7911 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3522.9 - 3.81E+06 - - - 2.4619 - 1.874 0.307 - 256.8 1 2 0 0.0023 8 0 0 0 4.56E+08 5.70E+08 - - - 3.202 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.18043.18043.2 0.00995 14-Aug K.LDYILGLK.L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 933.5535 0.81 32348 18043 2 933.555662 467.784 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3522.9 - 2.16E+06 - - - 2.2955 - 1.759 0.298 - 195.6 1 2 0 0.0021 8 0 0 0 4.56E+08 5.63E+08 - - - 2.9446 1 230117_WJC_METTL3_WT_vs_EV_F04.18044.18044.2 0.000122 16-Oct R.LSMMLLDSR[166.11].A "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1074.5441 5.76 32349 18044 2 1074.547349 538.2793 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.84 3523 - 1.24E+06 - - - 3.0171 - 2.074 0.477 - 406.2 1 2 0 0.0032 9 0 0 0 9.35E+07 1.62E+07 - - - 4.6735 0.988 230117_WJC_METTL3_WT_vs_EV_F04.18045.18045.2 0.71 14-Jul R.LYPVLLVK[136.11].Q "sp|Q7Z7F7|RM55_HUMAN,tr|X6RIW1|X6RIW1_HUMAN" 2 951.6248 1.15 32350 18045 2 951.627464 476.8197 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 8.59 3523.1 - 1.19E+06 - - - 2.7574 - 1.115 0.176 - 109.7 1 2 0 0.0026 8 0 0 0 2.61E+07 2.26E+07 - - - 0.6684 0.996 230117_WJC_METTL3_WT_vs_EV_F04.18057.18057.2 0.0216 16-Aug K.LFLVQLQEK[136.11].A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1124.6685 1.26 32358 18057 2 1124.67284 563.3415 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3524.4 - 370925 - - - 3.8625 - 1.346 0.304 - 121.8 1 2 0 0.0043 9 0 0 0 4.92E+07 3.91E+07 - - - 2.1446 0.9631 230117_WJC_METTL3_WT_vs_EV_F04.18060.18060.2 0.000461 20-Oct R.SALLVQLATAR.P "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1141.6819 2.04 32361 18060 2 1141.681587 571.8482 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 9.47 3524.8 - 214360 - - - -0.2812 - 2.34 0.4 - 244.2 1 1 0 -0.0003 11 0 0 0 4.06E+07 1.99E+07 - - - 4.2952 0.9956 230117_WJC_METTL3_WT_vs_EV_F04.18062.18062.2 1.29 14-Jul R.LLILMEAR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 967.5764 1.44 32363 18062 2 967.57998 484.7955 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6 3525.1 - 152010 - - - 3.7072 - 1.565 0.214 - 158.3 1 2 0 0.0036 8 0 0 0 4.41E+07 3.05E+07 - - - 1.9713 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.18065.18065.2 0.271 14-Aug R.LLILMEAR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 957.5681 1.45 32364 18065 2 957.570778 479.7913 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6 3525.5 - 133396 - - - 2.7726 - 1.791 0.354 - 196.6 1 2 0 0.0027 8 0 0 0 4.41E+07 3.05E+07 - - - 3.4124 0.999 230117_WJC_METTL3_WT_vs_EV_F04.18067.18067.2 0.00306 18-Aug K.IVLLMAYSGK.G "sp|Q9Y606|TRUA_HUMAN,tr|G8JLB3|G8JLB3_HUMAN,tr|F8W9U5|F8W9U5_HUMAN,tr|F5H168|F5H168_HUMAN,tr|F5H1B2|F5H1B2_HUMAN,tr|F5GY32|F5GY32_HUMAN,tr|F5GXL3|F5GXL3_HUMAN" 7 1093.6206 1.8 32366 18067 2 1093.620613 547.8176 tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3 8.59 3525.7 - 143669 - - - 0.0549 - 1.55 0.347 - 96.7 1 2 0 0.0001 10 0 0 0 1.74E+07 9.65E+06 - - - 2.8272 0.9956 230117_WJC_METTL3_WT_vs_EV_F04.18080.18080.2 1.46 16-Aug R.VVLPYLVPK[136.11].L sp|Q92616|GCN1_HUMAN 1 1034.662 1.13 32375 18080 2 1034.66389 518.3383 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.56 3527.3 - 1.36E+06 - - - 1.8711 - 1.224 0.203 - 167.6 1 2 0 0.0019 9 0 0 0 4.64E+07 4.12E+07 - - - 1.1245 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18081.18081.2 0.032 16-Sep K.VLEALQVLR.C "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1039.639 1.37 32376 18081 2 1039.640346 520.8268 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.97 3527.4 - 1.21E+06 - - - 1.3139 - 1.787 0.372 - 235.5 1 2 0 0.0014 9 0 0 0 6.67E+07 4.88E+07 - - - 3.4677 0.9825 230117_WJC_METTL3_WT_vs_EV_F04.18082.18082.2 2.15 20-Jul R.TINMQQSQVEK.Y "sp|Q8N6V9|TEX9_HUMAN,tr|H3BS88|H3BS88_HUMAN,tr|H0YLZ3|H0YLZ3_HUMAN" 3 1304.6395 5.91 32377 18082 2 1304.63762 653.327 Testis-expressed protein 9 OS=Homo sapiens OX=9606 GN=TEX9 PE=1 SV=1 5.66 3527.5 - 253831 - - - -1.4035 - 1.456 0.123 - 164.3 1 2 0 -0.0018 11 0 0 0 1.05E+07 1.78E+06 - - - 0.9652 0.8814 230117_WJC_METTL3_WT_vs_EV_F04.18083.18083.2 3.38 20-May K.VITC[160.03]GWDGLIK.L sp|O60508|PRP17_HUMAN 1 1260.6536 4.33 32378 18083 2 1260.654859 631.3341 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.8 3527.7 - 180152 - - - 0.9638 - 0.999 0.029 - 67.7 8 2 0 0.0012 11 0 0 0 4.63E+06 1.07E+06 - - - -1.1513 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18089.18089.2 0.00832 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 464.89 32382 18089 2 1006.572462 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3528.4 - 422130 - - - 2.5473 - 1.856 0.377 - 267.9 1 2 0 0.0026 9 0 0 0 8.27E+07 1.78E+05 - - - 3.6138 0.9954 230117_WJC_METTL3_WT_vs_EV_F04.18091.18091.2 0.411 12-Jun R.GWLNIVR.H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 856.4919 1.45 32384 18091 2 856.493061 429.2532 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 9.75 3528.5 - 233437 - - - 1.3298 - 1.108 0.225 - 162 1 2 0 0.0011 7 0 0 0 2.35E+07 1.61E+07 - - - 1.0274 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18094.18094.2 0.0101 14-Oct R.VVDLLVIK.G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 897.5899 2.11 32385 18094 2 897.591615 449.8022 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3528.9 - 5.02E+06 - - - 1.9051 - 1.838 0.485 - 281.4 1 2 0 0.0017 8 0 0 0 1.57E+08 7.42E+07 - - - 4.4584 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18098.18098.2 0.036 16-Aug K.LFLVQLQEK.A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1116.6543 1.15 32389 18098 2 1116.65573 559.3344 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3529.1 - 1.97E+06 - - - 1.2842 - 1.858 0.389 - 189.7 1 2 0 0.0014 9 0 0 0 4.34E+07 3.76E+07 - - - 3.706 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.18099.18099.2 0.00755 18-Aug K.YLAIAPPIIK.Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1097.6849 1.9 32390 18099 2 1097.687486 549.8497 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3529.2 - 1.16E+06 - - - 2.385 - 1.558 0.344 - 232.4 1 2 0 0.0026 10 0 0 0 1.87E+08 9.84E+07 - - - 2.8186 1 230117_WJC_METTL3_WT_vs_EV_F04.18106.18106.2 5.68E-05 20-Nov K.LIVAYVDDLDR.R "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1290.682 1.44 32395 18106 2 1290.686669 646.3483 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 3.93 3529.9 - 824018 - - - 3.643 - 2.092 0.487 - 473.4 1 2 0 0.0047 11 0 0 0 1.56E+07 1.08E+07 - - - 4.6333 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.18107.18107.2 0.061 18-Dec K.LAVNMVPFPR[166.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1152.6353 3.17 32396 18107 2 1152.637217 577.3249 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3530 - 3.88E+06 - - - 1.6588 - 1.807 0.266 - 636.5 1 2 0 0.0019 10 0 0 0 8.23E+08 2.60E+08 - - - 2.6566 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18113.18113.2 0.00125 18-Dec K.LAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1142.627 3.17 32401 18113 2 1142.628663 572.3208 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3530.8 - 9.15E+06 - - - 1.4248 - 2.303 0.348 - 654.6 1 2 0 0.0016 10 0 0 0 8.24E+08 2.60E+08 - - - 3.9394 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18115.18115.2 0.00515 14-Sep R.YQDILVFR.S "sp|P19623|SPEE_HUMAN,tr|K7EKM4|K7EKM4_HUMAN" 2 1052.5655 7.16 32402 18115 2 1052.567088 527.29 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.84 3531 - 5.93E+06 - - - 1.5267 - 1.831 0.421 - 251.4 1 2 0 0.0016 8 0 0 0 1.16E+08 1.63E+07 - - - 3.9742 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18116.18116.2 0.000484 14-Sep R.VVDLLVIK[136.11].G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 905.6041 2.11 32403 18116 2 905.60507 453.8093 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3531.1 - 6.06E+06 - - - 1.0656 - 1.725 0.405 - 210.3 1 2 0 0.001 8 0 0 0 1.57E+08 7.42E+07 - - - 3.6764 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18117.18117.2 0.00106 16-Sep K.LLQDFFNGK.E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1080.5604 10.26 32404 18117 2 1080.561348 541.2875 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3531.2 - 2.14E+06 - - - 0.8819 - 1.827 0.425 - 208.8 1 2 0 0.001 9 0 0 0 1.10E+08 1.07E+07 - - - 3.9233 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.18122.18122.2 0.0375 12-Jun R.AVFWDIK.N sp|Q6P2Q9|PRP8_HUMAN 1 877.4698 1.19 32407 18122 2 877.471146 439.7422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3531.8 - 950007 - - - 1.5454 - 1.314 0.268 - 142.1 1 2 0 0.0014 7 0 0 0 7.39E+07 6.23E+07 - - - 1.8853 1 230117_WJC_METTL3_WT_vs_EV_F04.18125.18125.2 2.64E-07 14/30 R.IINEPTAAAIAYGLDK.R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1658.8879 26.36 32410 18125 2 1658.891067 830.4512 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3532.2 - 670245 - - - 1.8868 - 2.604 0.531 - 321.3 1 2 0 0.0031 16 0 0 0 3.12E+07 1.18E+06 - - - 5.3149 1 230117_WJC_METTL3_WT_vs_EV_F04.18126.18126.2 0.000253 20-Nov K.LIVAYVDDLDR[166.11].R "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1300.6902 1.45 32411 18126 2 1300.692787 651.3524 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 3.93 3532.3 - 587667 - - - 1.9605 - 2.339 0.472 - 438.6 1 2 0 0.0026 11 0 0 0 1.57E+07 1.09E+07 - - - 4.8251 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.18131.18131.2 0.00696 16-Aug K.VLEALQVLR[166.11].C "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1049.6472 1.37 32414 18131 2 1049.646829 525.8309 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.97 3532.9 - 1.85E+06 - - - -0.4011 - 1.97 0.33 - 190.1 1 2 0 -0.0004 9 0 0 0 6.67E+07 4.89E+07 - - - 3.4398 0.9926 230117_WJC_METTL3_WT_vs_EV_F04.18133.18133.2 1.68 12-Jul R.ALLFIPR.R "sp|P08238|HS90B_HUMAN,sp|O00585|CCL21_HUMAN,tr|Q5VZ73|Q5VZ73_HUMAN" 3 828.5222 2.05 32416 18133 2 828.522991 415.2684 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 9.79 3533.1 - 1.08E+06 - - - 1.0042 - 1.438 0.069 - 207.8 1 2 0 0.0008 7 0 0 0 4.86E+08 2.37E+08 - - - 0.7014 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18139.18139.2 0.000903 18-Sep K.YLAIAPPIIK[136.11].Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1105.6991 1.91 32420 18139 2 1105.701009 553.8568 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3533.8 - 1.21E+06 - - - 1.7555 - 1.878 0.481 - 232.1 1 2 0 0.0019 10 0 0 0 1.86E+08 9.78E+07 - - - 4.3522 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18141.18141.2 0.000797 16-Sep K.ATSILEFYR[166.11].E "sp|P09001|RM03_HUMAN,tr|D6RC14|D6RC14_HUMAN,tr|E7ETU7|E7ETU7_HUMAN,tr|H0Y9G6|H0Y9G6_HUMAN,tr|E9PF06|E9PF06_HUMAN" 5 1108.5792 1.05 32422 18141 2 1108.580898 555.2969 "39S ribosomal protein L3, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL3 PE=1 SV=1" 6.05 3534.1 - 738474 - - - 1.5046 - 1.677 0.437 - 274.5 1 2 0 0.0017 9 0 0 0 2.92E+07 2.80E+07 - - - 3.7639 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.18152.18152.3 0.0602 Aug-36 K.LAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1142.627 2.84 32433 18152 3 1142.627317 381.883 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3535.5 - 88316.1 - - - 0.2468 - 1.473 0.24 - 109.1 1 2 0 0.0003 10 0 0 0 7.04E+06 2.48E+06 - - - 2.3468 0.9706 230117_WJC_METTL3_WT_vs_EV_F04.18154.18154.2 0.00027 20-Oct L.FVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1219.6561 -1 32435 18154 2 1219.657529 610.8353 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3535.8 - 128412 - - - 1.1823 - 1.883 0.393 - 276 1 1 0 0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 3.6553 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.18158.18158.2 0.0237 12-Jun R.AVFWDIK[136.11].N sp|Q6P2Q9|PRP8_HUMAN 1 885.484 1.2 32437 18158 2 885.485062 443.7493 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3536.3 - 3.39E+06 - - - 1.2106 - 1.203 0.302 - 158.9 1 2 0 0.0011 7 0 0 0 7.37E+07 6.13E+07 - - - 1.8568 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18160.18160.2 0.000258 18-Oct R.VLITTDLLAR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 1123.684 1.45 32439 18160 2 1123.686636 562.8493 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3536.5 - 2.10E+06 - - - 2.3192 - 2.131 0.44 - 285.1 1 2 0 0.0026 10 0 0 0 3.30E+08 2.27E+08 - - - 4.4019 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.18168.18168.2 0.0254 16-Sep R.LIDFLEC[160.03]GK[136.11].T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1101.562 0.83 32445 18168 2 1101.559554 551.7883 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3537.5 - 8.00E+06 - - - -2.2041 - 1.764 0.369 - 206.6 1 2 0 -0.0024 9 0 0 0 1.59E+08 1.92E+08 - - - 3.4077 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18169.18169.2 0.000105 16-Sep R.LIDFLEC[160.03]GK.T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1093.5478 0.77 32446 18169 2 1093.551114 547.7812 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3537.5 - 7.62E+06 - - - 3.047 - 1.739 0.528 - 197.8 1 2 0 0.0033 9 0 0 0 1.61E+08 2.09E+08 - - - 4.5405 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.18170.18170.2 0.0806 12-Jul R.LVVLPFR[166.11].R sp|Q10570|CPSF1_HUMAN 1 852.5461 2.18 32447 18170 2 852.548273 427.2803 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 9.75 3537.6 - 911241 - - - 2.5735 - 1.448 0.183 - 137.1 1 2 0 0.0022 7 0 0 0 3.09E+07 1.42E+07 - - - 1.5649 1 230117_WJC_METTL3_WT_vs_EV_F04.18173.18173.2 0.000157 22-Dec R.APVVAIAVLDGR[166.11].G "sp|Q15334|L2GL1_HUMAN,tr|A0A087WW77|A0A087WW77_HUMAN" 2 1189.7058 2 32450 18173 2 1189.699956 595.8602 Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens OX=9606 GN=LLGL1 PE=1 SV=3 5.88 3538 - 225981 - - - -4.9357 - 2.651 0.507 - 434.2 1 2 0 -0.0059 12 0 0 0 1.04E+07 5.19E+06 - - - 5.3491 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18175.18175.2 0.000587 18-Aug R.VLITTDLLAR.G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 1113.6758 1.45 32451 18175 2 1113.678277 557.8452 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3538.2 - 2.04E+07 - - - 2.2601 - 1.73 0.422 - 222.1 1 2 0 0.0025 10 0 0 0 3.29E+08 2.27E+08 - - - 3.6871 1 230117_WJC_METTL3_WT_vs_EV_F04.18177.18177.2 3.02E-05 18-Oct K.FYALDPSFPR.M sp|Q08J23|NSUN2_HUMAN 1 1211.5975 1.56 32452 18177 2 1211.600494 606.806 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3538.5 - 661168 - - - 2.4637 - 1.977 0.553 - 330.4 1 2 0 0.003 10 0 0 0 1.03E+07 6.56E+06 - - - 5.027 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.18184.18184.2 0.00182 18-Jul K.MLLAISELNK.N sp|Q9H694|BICC1_HUMAN 1 1130.6369 3.18 32457 18184 2 1130.637908 566.3257 Protein bicaudal C homolog 1 OS=Homo sapiens OX=9606 GN=BICC1 PE=1 SV=2 5.75 3539.4 - 242995 - - - 0.8641 - 1.624 0.303 - 102.6 1 2 0 0.001 10 0 0 0 6.40E+06 2.01E+06 - - - 2.6321 1 230117_WJC_METTL3_WT_vs_EV_F04.18191.18191.2 1.14E-05 28-Nov R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 10.45 32463 18191 2 1484.91406 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3540.2 - 153788 - - - 4.1585 - 2.165 0.507 - 311.8 1 2 0 0.0062 15 0 0 0 7.26E+06 6.95E+05 - - - 4.6828 0.9663 230117_WJC_METTL3_WT_vs_EV_F04.18195.18195.2 0.00678 18-Oct N.MVVDAVLAIK.Y "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1057.6206 16.33 32466 18195 2 1057.621418 529.8176 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.59 3540.8 - 810288 - - - 0.8179 - 1.801 0.383 - 263.5 1 1 0 0.0009 10 0 0 0 2.53E+07 1.55E+06 - - - 3.5118 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18196.18196.2 0.00427 14-Sep R.IGVMSLIR[166.11].K "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 897.5345 1.44 32467 18196 2 897.535972 449.7745 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 3540.8 - 736172 - - - 1.6077 - 1.682 0.355 - 247.7 1 2 0 0.0014 8 0 0 0 3.56E+07 2.47E+07 - - - 3.2308 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.18200.18200.2 0.0299 14-Jul R.IGVMSLIR.K "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 887.5263 1.44 32469 18200 2 887.528312 444.7704 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 3541.3 - 3.79E+06 - - - 2.3132 - 1.489 0.311 - 124.1 1 2 0 0.0021 8 0 0 0 3.56E+07 2.47E+07 - - - 2.5381 0.9665 230117_WJC_METTL3_WT_vs_EV_F04.18201.18201.2 0.0273 14-Jul R.VPTIFPLR[166.11].G sp|Q96EK4|THA11_HUMAN 1 951.5781 43.45 32470 18201 2 951.585718 476.7963 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 9.72 3541.4 - 1.12E+06 - - - 7.9972 - 1.42 0.341 - 148.9 1 2 0 0.0076 8 0 0 0 5.57E+08 1.28E+07 - - - 2.6148 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18203.18203.2 0.000598 20-Oct K.LDPGLIMEQVK[136.11].V sp|Q9Y5L4|TIM13_HUMAN 1 1249.6832 2.33 32472 18203 2 1249.685728 625.8489 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3541.7 - 451349 - - - 2.0549 - 1.745 0.386 - 295.5 1 2 0 0.0026 11 0 0 0 1.48E+07 6.34E+06 - - - 3.3973 1 230117_WJC_METTL3_WT_vs_EV_F04.18205.18205.2 5.01E-08 13/24 -.MLSEVLLVSAPGK[136.11].V "sp|Q03426|KIME_HUMAN,tr|F5GXC0|F5GXC0_HUMAN,tr|F5H163|F5H163_HUMAN,tr|F5H092|F5H092_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|F5H368|F5H368_HUMAN,tr|A0A1W2PS16|A0A1W2PS16_HUMAN" 7 1350.7672 15.34 32474 18205 2 1350.761327 676.3909 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 5.75 3542 - 280192 - - - -4.3657 - 2.263 0.551 - 508 1 2 0 -0.0059 13 0 0 0 8.73E+07 5.69E+06 - - - 5.2049 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.18206.18206.2 9.13E-05 26-Nov K.IIVPNSTAGLIIGK.G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VW64|F8VW64_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|M0R1A0|M0R1A0_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|G8JLA5|G8JLA5_HUMAN" 8 1394.8497 2.41 32475 18206 2 1394.857626 698.4321 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.75 3542.1 - 248048 - - - 5.6816 - 1.799 0.43 - 213.7 1 2 0 0.0079 14 0 0 0 3.46E+06 1.44E+06 - - - 3.6881 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.18211.18211.2 0.00116 15/22 R.FLAVGLVDNTVR.L sp|Q15393|SF3B3_HUMAN 1 1302.7296 1.12 32479 18211 2 1302.735653 652.3721 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3542.7 - 1.92E+06 - - - 4.6571 - 2.48 0.421 - 791.3 1 2 0 0.0061 12 0 0 0 9.61E+07 8.62E+07 - - - 4.5384 1 230117_WJC_METTL3_WT_vs_EV_F04.18212.18212.2 0.00125 15/22 R.FLAVGLVDNTVR[166.11].L sp|Q15393|SF3B3_HUMAN 1 1312.7379 1.12 32480 18212 2 1312.741258 657.3762 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3542.9 - 1.85E+06 - - - 2.5915 - 2.5 0.494 - 904.5 1 2 0 0.0034 12 0 0 0 9.61E+07 8.61E+07 - - - 5.0995 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.18213.18213.2 0.00398 20-Jul K.LVAASQAALGL.- "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 1012.5917 - 32481 18213 2 1012.594298 507.3031 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.52 3543 - 676456 - - - 2.5696 - 1.742 0.331 - 71.5 1 2 0 0.0026 11 0 0 0 - - - - - 2.9864 0.9947 230117_WJC_METTL3_WT_vs_EV_F04.18214.18214.2 0.0402 16-Dec K.TLGILGLGR[166.11].L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 908.5683 2.02 32482 18214 2 908.571347 455.2914 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3543.1 - 556106 - - - 3.3844 - 1.905 0.095 - 463.4 1 2 0 0.0031 9 0 0 0 2.21E+08 1.10E+08 - - - 1.6062 0.9939 230117_WJC_METTL3_WT_vs_EV_F04.18215.18215.2 0.00141 22-Nov R.APVVAIAVLDGR.G "sp|Q15334|L2GL1_HUMAN,tr|A0A087WW77|A0A087WW77_HUMAN" 2 1179.6976 2 32483 18215 2 1179.692716 590.8561 Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens OX=9606 GN=LLGL1 PE=1 SV=3 5.88 3543.2 - 463207 - - - -4.1044 - 2.488 0.347 - 360.1 1 2 0 -0.0048 12 0 0 0 1.04E+07 5.19E+06 - - - 4.0007 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.18216.18216.2 0.00715 18-Nov R.ILELDQELIK[136.11].A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1220.7108 1.31 32484 18216 2 1220.713778 611.3627 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3543.4 - 435910 - - - 2.4764 - 2.244 0.172 - 302.3 1 2 0 0.003 10 0 0 0 2.60E+07 1.99E+07 - - - 2.5665 0.9958 230117_WJC_METTL3_WT_vs_EV_F04.18217.18217.2 0.15 14-Jun R.FLFPEGIK[136.11].G "sp|O75891|AL1L1_HUMAN,sp|Q3SY69|AL1L2_HUMAN,tr|C9IZ36|C9IZ36_HUMAN,tr|A0A494C1M4|A0A494C1M4_HUMAN" 4 957.5415 1.32 32485 18217 2 957.541404 479.778 Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L1 PE=1 SV=2 6 3543.5 - 333694 - - - -0.1044 - 1.133 0.276 - 79 1 2 0 -0.0001 8 0 0 0 7.83E+06 5.93E+06 - - - 1.4561 1 230117_WJC_METTL3_WT_vs_EV_F04.18221.18221.2 0.000136 26-Oct K.VLIPSYAAGSIIGK.G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|F8W659|F8W659_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|F8VYI3|F8VYI3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|I3L2B5|I3L2B5_HUMAN" 8 1387.8075 2.2 32489 18221 2 1387.809609 694.911 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.56 3544 - 122102 - - - 1.5182 - 1.933 0.544 - 181.4 1 2 0 0.0021 14 0 0 0 5.87E+06 2.67E+06 - - - 4.7122 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18225.18225.2 0.0118 13/20 K.LALDVEIATYR.K "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1262.6871 50.88 32491 18225 2 1262.691026 632.3508 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 3544.6 - 6.89E+06 - - - 3.1465 - 2.73 0.323 - 817.6 1 2 0 0.004 11 0 0 0 1.89E+08 3.70E+06 - - - 4.1423 0.9802 230117_WJC_METTL3_WT_vs_EV_F04.18226.18226.2 0.185 16-Dec K.TLGILGLGR.L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 898.56 1.99 32492 18226 2 898.565111 450.2873 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3544.6 - 4.54E+06 - - - 5.6858 - 1.847 0.135 - 445.7 1 2 0 0.0051 9 0 0 0 2.23E+08 1.12E+08 - - - 1.8116 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.18227.18227.2 0.0311 18-Dec R.ILELDQELIK.A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1212.6966 1.31 32493 18227 2 1212.699746 607.3556 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3544.7 - 2.25E+06 - - - 2.6313 - 2.092 0.259 - 362.5 1 2 0 0.0032 10 0 0 0 2.65E+07 2.02E+07 - - - 3.0133 0.9946 230117_WJC_METTL3_WT_vs_EV_F04.18228.18228.2 0.0315 16-Jun R.YYIDADLLR[166.11].E sp|Q7Z3B4|NUP54_HUMAN 1 1150.5898 2.05 32494 18228 2 1150.595239 576.3022 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.21 3544.8 - 2.24E+06 - - - 4.7315 - 1.424 0.325 - 99.5 1 2 0 0.0054 9 0 0 0 4.75E+07 2.31E+07 - - - 2.4623 1 230117_WJC_METTL3_WT_vs_EV_F04.18230.18230.2 0.00201 22-Nov K.IPGIIIAASAVR.A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1179.7339 2.68 32496 18230 2 1179.73861 590.8742 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3545 - 1.05E+06 - - - 3.956 - 2.437 0.498 - 462.7 1 2 0 0.0047 12 0 0 0 1.96E+07 7.32E+06 - - - 5.0615 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.18231.18231.2 0.657 20-Nov R.VVGVLLGSWQK[136.11].K "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 1192.7059 1.69 32497 18231 2 1192.710159 597.3602 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 8.72 3545.2 - 883299 - - - 3.534 - 2.156 0.237 - 389.8 1 2 0 0.0042 11 0 0 0 1.81E+07 1.08E+07 - - - 2.8685 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18232.18232.2 0.00266 20-Oct R.LGIPDAVSYIK.K sp|O94874|UFL1_HUMAN 1 1174.6598 0.86 32498 18232 2 1174.662915 588.3372 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.83 3545.3 - 854885 - - - 2.6731 - 2.122 0.389 - 168.7 1 2 0 0.0031 11 0 0 0 1.58E+07 1.85E+07 - - - 3.9485 0.997 230117_WJC_METTL3_WT_vs_EV_F04.18235.18235.2 0.0184 20-Dec K.LALDMEISAYR.K "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN" 2 1280.6435 1.42 32501 18235 2 1280.650634 641.329 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.37 3545.7 - 426946 - - - 5.5917 - 2.578 0.359 - 711.4 1 2 0 0.0072 11 0 0 0 6.77E+06 4.75E+06 - - - 4.2522 0.9951 230117_WJC_METTL3_WT_vs_EV_F04.18236.18236.2 7.05E-05 26-Nov K.VLIPSYAAGSIIGK[136.11].G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|F8W659|F8W659_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|F8VYI3|F8VYI3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|I3L2B5|I3L2B5_HUMAN" 8 1395.8217 2.2 32502 18236 2 1395.81736 698.9181 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.56 3545.8 - 284921 - - - -3.1107 - 2.028 0.334 - 258.9 1 2 0 -0.0043 14 0 0 0 5.87E+06 2.67E+06 - - - 3.2809 0.9726 230117_WJC_METTL3_WT_vs_EV_F04.18239.18239.2 1.84 14-Jul R.DVDFELIK.V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 977.507 3.52 32504 18239 2 977.510207 489.7608 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3546.3 - 310532 - - - 3.3186 - 1.121 0.127 - 106.2 1 2 0 0.0032 8 0 0 0 9.68E+08 2.75E+08 - - - 0.3225 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.18240.18240.2 0.00083 16-Aug R.YYIDADLLR.E sp|Q7Z3B4|NUP54_HUMAN 1 1140.5815 2.05 32505 18240 2 1140.586777 571.298 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.21 3546.4 - 5.75E+06 - - - 4.6047 - 1.596 0.463 - 176.4 1 2 0 0.0053 9 0 0 0 4.75E+07 2.31E+07 - - - 3.8116 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18246.18246.2 0.0365 20-Oct K.NLIDAGVDALR[166.11].V "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1165.6331 0.87 32511 18246 2 1165.635737 583.8238 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.21 3547.1 - 292202 - - - 2.2992 - 1.97 0.341 - 242.2 1 2 0 0.0027 11 0 0 0 2.77E+06 3.20E+06 - - - 3.393 0.9649 230117_WJC_METTL3_WT_vs_EV_F04.18249.18249.2 0.282 18-Jun R.AFIGIGFGDR.G "sp|Q9NVZ3|NECP2_HUMAN,tr|F6SKB8|F6SKB8_HUMAN" 2 1051.5451 0.92 32514 18249 2 1051.548344 526.7798 Adaptin ear-binding coat-associated protein 2 OS=Homo sapiens OX=9606 GN=NECAP2 PE=1 SV=1 5.88 3547.5 - 188564 - - - 3.104 - 1.325 0.061 - 78.2 3 2 0 0.0033 10 0 0 0 1.94E+06 2.10E+06 - - - 0.0629 1 230117_WJC_METTL3_WT_vs_EV_F04.18251.18251.2 5.20E-07 13/28 R.LGALQGDPEALTLYR.E sp|Q9P253|VPS18_HUMAN 1 1615.857 7.6 32516 18251 2 1615.860882 808.9358 Vacuolar protein sorting-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=VPS18 PE=1 SV=2 4.37 3547.7 - 113385 - - - 2.4198 - 2.404 0.573 - 478.8 1 2 0 0.0039 15 0 0 0 1.52E+06 2.00E+05 - - - 5.4284 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18258.18258.2 0.00019 22-Nov K.LIVDPALDPALR.R "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN,tr|C9J2Z9|C9J2Z9_HUMAN" 3 1291.75 3.02 32521 18258 2 1291.753906 646.8823 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.21 3548.6 - 1.35E+06 - - - 3.0339 - 2.031 0.467 - 362.8 1 2 0 0.0039 12 0 0 0 1.41E+07 4.68E+06 - - - 4.3533 0.9707 230117_WJC_METTL3_WT_vs_EV_F04.18262.18262.2 2.21 14-Jul R.FLFPEGIK.G "sp|O75891|AL1L1_HUMAN,sp|Q3SY69|AL1L2_HUMAN,tr|C9IZ36|C9IZ36_HUMAN,tr|A0A494C1M4|A0A494C1M4_HUMAN" 4 949.5273 1.21 32525 18262 2 949.531147 475.7709 Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L1 PE=1 SV=2 6 3549.1 - 473349 - - - 4.0473 - 1.247 0.122 - 145.4 1 2 0 0.0038 8 0 0 0 8.72E+06 7.23E+06 - - - 0.6066 0.9906 230117_WJC_METTL3_WT_vs_EV_F04.18267.18267.2 0.107 22-Nov K.VLETVGVFEVPK[136.11].Q "sp|Q9Y2S7|PDIP2_HUMAN,tr|B4DEM9|B4DEM9_HUMAN" 2 1323.753 5.25 32530 18267 2 1323.761332 662.8838 Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1 4.53 3549.8 - 155974 - - - 6.329 - 1.849 0.33 - 291 1 2 0 0.0084 12 0 0 0 9.31E+06 1.77E+06 - - - 3.093 0.9919 230117_WJC_METTL3_WT_vs_EV_F04.18276.18276.2 0.597 12-Jun K.MIADFLR.E "sp|Q96R72|OR4K3_HUMAN,sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 4 864.4528 4.47 32538 18276 2 864.453664 433.2337 Olfactory receptor 4K3 OS=Homo sapiens OX=9606 GN=OR4K3 PE=3 SV=3 5.59 3550.6 - 918217 - - - 1.0469 - 1.344 0.089 - 161.6 1 2 0 0.0009 7 0 0 0 4.52E+07 1.01E+07 - - - 0.6349 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.18277.18277.2 0.00828 14-Aug K.LWGVIDVK.R "sp|Q9UHD1|CHRD1_HUMAN,tr|E9PHZ2|E9PHZ2_HUMAN" 2 928.5382 3.23 32539 18277 2 928.540243 465.2764 Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2 5.84 3550.6 - 743810 - - - 2.197 - 1.564 0.284 - 191.2 1 2 0 0.002 8 0 0 0 1.26E+07 3.91E+06 - - - 2.4869 1 230117_WJC_METTL3_WT_vs_EV_F04.18278.18278.2 0.0142 14/22 K.IPGIIIAASAVR[166.11].A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1189.7422 2.68 32540 18278 2 1189.745197 595.8784 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3550.7 - 690961 - - - 2.5081 - 2.603 0.497 - 782 1 2 0 0.003 12 0 0 0 1.96E+07 7.32E+06 - - - 5.2281 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.18279.18279.2 1.2 12-Sep K.ILVDLLK.L "sp|Q6P582|MZT2A_HUMAN,sp|Q6NZ67|MZT2B_HUMAN,tr|H7C202|H7C202_HUMAN,tr|B8ZZ87|B8ZZ87_HUMAN,tr|A0A494C0V9|A0A494C0V9_HUMAN,tr|H7BZ50|H7BZ50_HUMAN,tr|H7C173|H7C173_HUMAN" 7 812.5371 2.18 32541 18279 2 812.538864 407.2758 Mitotic-spindle organizing protein 2A OS=Homo sapiens OX=9606 GN=MZT2A PE=1 SV=2 5.84 3550.7 - 579060 - - - 2.1205 - 2.114 0.176 - 226.3 1 2 0 0.0017 7 0 0 0 9.89E+06 4.53E+06 - - - 2.7123 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.18281.18281.2 1.64 16-Aug R.LALILC[160.03]VTK.A sp|P31944|CASPE_HUMAN 1 1029.6256 999 32543 18281 2 1029.627366 515.8201 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 8.22 3550.9 - 525673 - - - 1.6773 - 1.739 0.154 - 83.2 1 2 0 0.0017 9 0 0 0 6.15E+06 0.00E+00 - - - 1.7787 0.9919 230117_WJC_METTL3_WT_vs_EV_F04.18282.18282.2 0.695 12-Jun K.AFFSPFR.L sp|Q92626|PXDN_HUMAN 1 870.4388 0.84 32544 18282 2 870.441023 436.2267 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 9.79 3551 - 498702 - - - 2.5263 - 1.208 0.166 - 131.5 1 2 0 0.0022 7 0 0 0 1.07E+07 1.27E+07 - - - 0.8651 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18284.18284.2 0.162 14-Jul K.DVIEEYFK.C sp|P25398|RS12_HUMAN 1 1041.5019 2.3 32546 18284 2 1041.503657 521.7582 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.14 3551.1 - 358645 - - - 1.7081 - 1.716 0.333 - 176.3 1 2 0 0.0018 8 0 0 0 5.61E+06 2.44E+06 - - - 3.1286 0.9746 230117_WJC_METTL3_WT_vs_EV_F04.18286.18286.2 0.0211 22-Nov L.PLIPIVVEQTGR.G sp|Q16740|CLPP_HUMAN 1 1320.7765 1.68 32548 18286 2 1320.77764 661.3955 "ATP-dependent Clp protease proteolytic subunit, mitochondrial OS=Homo sapiens OX=9606 GN=CLPP PE=1 SV=1" 6.43 3551.3 - 185580 - - - 0.8359 - 2.141 0.407 - 320.8 1 1 0 0.0011 12 0 0 0 4.69E+06 2.80E+06 - - - 4.0498 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18290.18290.2 0.000682 16-Sep K.GIFLGDQWR.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1090.556 2.62 32550 18290 2 1090.558413 546.2853 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3551.8 - 7.79E+06 - - - 2.2319 - 1.597 0.413 - 306.5 1 2 0 0.0024 9 0 0 0 1.10E+08 4.20E+07 - - - 3.445 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18291.18291.2 0.0444 18-Nov R.YLYTLVITDK[136.11].E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1235.6893 1.48 32551 18291 2 1235.692413 618.8519 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3551.9 - 2.98E+06 - - - 2.5265 - 2.176 0.363 - 283 1 2 0 0.0031 10 0 0 0 6.91E+08 4.66E+08 - - - 3.8913 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18292.18292.2 6.01E-05 18-Nov R.YLYTLVITDK.E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1227.6751 1.48 32552 18292 2 1227.677493 614.8448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3551.9 - 3.21E+06 - - - 1.9565 - 2.095 0.306 - 328.2 1 2 0 0.0024 10 0 0 0 6.91E+08 4.66E+08 - - - 3.3647 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.18293.18293.2 0.867 12-Jul K.MIADFLR[166.11].E "sp|Q96R72|OR4K3_HUMAN,sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 4 874.461 4.47 32553 18293 2 874.462684 438.2378 Olfactory receptor 4K3 OS=Homo sapiens OX=9606 GN=OR4K3 PE=3 SV=3 5.59 3552 - 1.17E+06 - - - 1.8926 - 1.545 0.161 - 249 1 2 0 0.0017 7 0 0 0 4.51E+07 1.01E+07 - - - 1.608 0.9705 230117_WJC_METTL3_WT_vs_EV_F04.18295.18295.2 0.000467 20-Oct R.LLDLVVQPVPR.P sp|Q8WYP5|ELYS_HUMAN 1 1247.7602 1.68 32555 18295 2 1247.762904 624.8874 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.84 3552.2 - 776788 - - - 2.2007 - 2.065 0.403 - 415.3 1 1 0 0.0027 11 0 0 0 7.05E+06 4.21E+06 - - - 3.9783 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18297.18297.2 9.73E-05 13/22 K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 351.13 32557 18297 2 1382.682048 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3552.3 - 614824 - - - -0.7102 - 2.201 0.42 - 491.8 1 2 0 -0.001 12 0 0 0 1.47E+07 4.19E+04 - - - 4.2186 0.9703 230117_WJC_METTL3_WT_vs_EV_F04.18299.18299.2 0.000119 20-Dec R.LLDLVVQPVPR[166.11].P sp|Q8WYP5|ELYS_HUMAN 1 1257.7684 1.68 32559 18299 2 1257.769452 629.8915 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.84 3552.5 - 552549 - - - 0.8141 - 2.249 0.339 - 675.8 1 1 0 0.001 11 0 0 0 7.05E+06 4.21E+06 - - - 3.7371 0.9231 230117_WJC_METTL3_WT_vs_EV_F04.18301.18301.2 0.0261 18-Sep S.GVAVSDGVIK.V "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PS23|E9PS23_HUMAN" 4 943.5338 2.01 32561 18301 2 943.535531 472.7742 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 5.84 3552.7 - 726724 - - - 1.7858 - 1.743 0.243 - 166.4 1 1 0 0.0017 10 0 0 0 4.07E+08 2.03E+08 - - - 2.3861 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.18302.18302.2 0.000126 22-Sep K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 7.73 32562 18302 2 1332.739305 667.3774 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3552.8 - 472207 - - - -0.6348 - 1.85 0.373 - 207.5 1 2 0 -0.0008 12 0 0 0 6.28E+09 8.13E+08 - - - 3.4144 0.9849 230117_WJC_METTL3_WT_vs_EV_F04.18305.18305.2 0.0866 14-Jul K.IGGIFAFK.V "sp|P22307|SCP2_HUMAN,tr|H0YF61|H0YF61_HUMAN" 2 851.4905 1.77 32565 18305 2 851.487545 426.7525 Sterol carrier protein 2 OS=Homo sapiens OX=9606 GN=SCP2 PE=1 SV=2 8.75 3553.1 - 332946 - - - -3.4997 - 1.512 0.263 - 87.3 1 2 0 -0.003 8 0 0 0 4.44E+06 2.51E+06 - - - 2.2295 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18308.18308.2 0.00133 16-Sep K.GIFLGDQWR[166.11].D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1100.5642 2.61 32566 18308 2 1100.566791 551.2894 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3553.6 - 4.57E+06 - - - 2.3097 - 1.682 0.425 - 305.1 1 2 0 0.0025 9 0 0 0 1.10E+08 4.20E+07 - - - 3.6836 0.8584 230117_WJC_METTL3_WT_vs_EV_F04.18309.18309.2 2.65 12-Jul R.SILEYLR.V sp|Q8N1G4|LRC47_HUMAN 1 892.5018 1.57 32567 18309 2 892.499572 447.2582 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 5.72 3553.6 - 2.33E+06 - - - -2.5165 - 1.117 0.072 - 201 1 2 0 -0.0022 7 0 0 0 2.49E+07 1.59E+07 - - - -0.0773 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.18310.18310.2 0.357 16-Oct R.FLSGLELVK.Q "sp|Q96S44|PRPK_HUMAN,tr|Q5JZ02|Q5JZ02_HUMAN" 2 1004.5906 1.02 32568 18310 2 1004.593504 503.3026 EKC\KEOPS complex subunit TP53RK OS=Homo sapiens OX=9606 GN=TP53RK PE=1 SV=2 6 3553.8 - 2.43E+06 - - - 2.8579 - 1.517 0.161 - 202.2 1 2 0 0.0029 9 0 0 0 2.22E+07 2.17E+07 - - - 1.4349 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18313.18313.2 0.00202 20-Oct R.ILDVGFEEELK[136.11].Q "sp|Q9NVP1|DDX18_HUMAN,tr|H7C452|H7C452_HUMAN" 2 1298.6849 1.19 32571 18313 2 1298.686447 650.3497 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 4 3554.1 - 1.36E+06 - - - 1.165 - 1.862 0.342 - 310.2 1 2 0 0.0015 11 0 0 0 8.41E+06 7.05E+06 - - - 3.2483 1 230117_WJC_METTL3_WT_vs_EV_F04.18315.18315.2 3.43E-05 16-Nov K.YMAEALLLR.A sp|O94826|TOM70_HUMAN 1 1078.5845 1.76 32573 18315 2 1078.58971 540.2995 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 6 3554.4 - 848870 - - - 4.8286 - 2.295 0.504 - 443.7 1 2 0 0.0052 9 0 0 0 7.85E+06 4.45E+06 - - - 5.1653 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.18316.18316.2 0.0218 12-Jul R.YDLWNLK[136.11].Y sp|Q9ULW3|ABT1_HUMAN 1 958.5004 0.59 32574 18316 2 958.503187 480.2575 Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1 5.83 3554.5 - 629336 - - - 2.9411 - 1.454 0.296 - 145.2 1 2 0 0.0028 7 0 0 0 8.53E+06 1.46E+07 - - - 2.4124 0.9222 230117_WJC_METTL3_WT_vs_EV_F04.18317.18317.2 2.24 14-Jun K.DLYSALIK.L sp|O75844|FACE1_HUMAN 1 921.5171 1.11 32575 18317 2 921.519036 461.7658 CAAX prenyl protease 1 homolog OS=Homo sapiens OX=9606 GN=ZMPSTE24 PE=1 SV=2 5.83 3554.7 - 527905 - - - 2.064 - 1.107 0.008 - 97.5 3 2 0 0.0019 8 0 0 0 2.26E+07 2.03E+07 - - - -0.8071 1 230117_WJC_METTL3_WT_vs_EV_F04.18319.18319.2 9.24E-09 26-Dec K.FYGPEGPYGVFAGR.D sp|O00264|PGRC1_HUMAN 1 1515.7147 1.41 32577 18319 2 1515.716332 758.8646 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3554.9 - 398448 - - - 1.1005 - 2.444 0.652 - 512.7 1 2 0 0.0017 14 0 0 0 3.74E+07 2.65E+07 - - - 6.0987 1 230117_WJC_METTL3_WT_vs_EV_F04.18320.18320.2 8.68E-11 14/26 K.FYGPEGPYGVFAGR[166.11].D sp|O00264|PGRC1_HUMAN 1 1525.7229 1.41 32578 18320 2 1525.724989 763.8687 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3555.1 - 390065 - - - 1.3469 - 2.552 0.667 - 720.3 1 2 0 0.0021 14 0 0 0 3.74E+07 2.65E+07 - - - 6.3179 0.9392 230117_WJC_METTL3_WT_vs_EV_F04.18322.18322.2 0.015 22-Oct H.IISELILTAQER[166.11].D sp|Q96I24|FUBP3_HUMAN 1 1394.8009 1.7 32580 18322 2 1394.80545 698.4077 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3555.3 - 208240 - - - 3.298 - 2.278 0.338 - 282.2 1 1 0 0.0046 12 0 0 0 5.25E+06 3.10E+06 - - - 3.7023 0.9594 230117_WJC_METTL3_WT_vs_EV_F04.18326.18326.2 0.00233 22-Aug R.PVLLQVAESAYR[166.11].F sp|Q9UJS0|CMC2_HUMAN 1 1354.7484 1.78 32583 18326 2 1354.749611 678.3815 Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13 PE=1 SV=2 6.43 3555.8 - 103984 - - - 0.8784 - 1.784 0.357 - 233.4 1 1 0 0.0012 12 0 0 0 2.55E+06 1.43E+06 - - - 3.2005 1 230117_WJC_METTL3_WT_vs_EV_F04.18332.18332.2 0.000217 13/18 R.IPLNPYLNLH.S "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 1192.6604 - 32587 18332 2 1192.660048 597.3375 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.74 3556.6 - 1.81E+06 - - - -0.332 - 2.501 0.503 - 679.6 1 1 0 -0.0004 10 0 0 0 - - - - - 5.3148 0.9472 230117_WJC_METTL3_WT_vs_EV_F04.18334.18334.2 2.41 12-Apr R.MNSLTFK.K "sp|Q96N67|DOCK7_HUMAN,tr|A0A1B0GWE0|A0A1B0GWE0_HUMAN" 2 839.4211 1.71 32589 18334 2 839.422033 420.7178 Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4 8.5 3556.8 - 1.09E+06 - - - 1.0817 - 0.808 0.188 - 50.9 7 2 0 0.0009 7 0 0 0 9.96E+06 5.81E+06 - - - -0.6237 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.18337.18337.2 0.00495 14-Aug R.GFGFVQFK[136.11].N "sp|Q9NW13|RBM28_HUMAN,tr|C9JE21|C9JE21_HUMAN" 2 936.4949 0.78 32592 18337 2 936.496592 469.2547 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 8.75 3557.1 - 921050 - - - 1.8185 - 1.39 0.28 - 191.1 1 2 0 0.0017 8 0 0 0 1.57E+07 2.00E+07 - - - 2.1017 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18342.18342.2 0.00359 16-Aug R.ILFLDPSGK[136.11].V sp|O95881|TXD12_HUMAN 1 996.5735 1.09 32595 18342 2 996.574833 499.294 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3557.8 - 1.28E+07 - - - 1.3045 - 1.726 0.39 - 184.2 1 2 0 0.0013 9 0 0 0 4.99E+08 4.56E+08 - - - 3.5002 1 230117_WJC_METTL3_WT_vs_EV_F04.18345.18345.2 4.24E-05 20-Dec R.MLDMGFEPQIR[166.11].R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1345.6398 1.18 32598 18345 2 1345.640948 673.8272 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3558 - 1.64E+06 - - - 0.8546 - 2.227 0.489 - 581.1 1 2 0 0.0011 11 0 0 0 8.65E+07 7.31E+07 - - - 4.8184 1 230117_WJC_METTL3_WT_vs_EV_F04.18346.18346.2 0.000119 20-Oct R.MLDMGFEPQIR.R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1335.6315 1.19 32599 18346 2 1335.633515 668.823 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3558.2 - 1.44E+06 - - - 1.4877 - 2.118 0.514 - 398.7 1 2 0 0.002 11 0 0 0 8.68E+07 7.31E+07 - - - 4.867 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18347.18347.2 0.0243 18-Sep K.FYALDPSFPR[166.11].M sp|Q08J23|NSUN2_HUMAN 1 1221.6058 1.59 32600 18347 2 1221.608422 611.8102 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3558.3 - 1.28E+06 - - - 2.1635 - 1.871 0.382 - 251 1 2 0 0.0026 10 0 0 0 1.84E+07 1.16E+07 - - - 3.6103 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.18348.18348.2 0.28 12-Jun K.FALPYIR.D "sp|P06132|DCUP_HUMAN,tr|Q5T446|Q5T446_HUMAN,tr|A0A1B0GVN9|A0A1B0GVN9_HUMAN,tr|H0Y5R6|H0Y5R6_HUMAN,tr|A0A494C0S8|A0A494C0S8_HUMAN,tr|A0A494C0Q8|A0A494C0Q8_HUMAN,tr|A0A494C085|A0A494C085_HUMAN" 7 878.5014 1.37 32601 18348 2 878.501598 440.258 Uroporphyrinogen decarboxylase OS=Homo sapiens OX=9606 GN=UROD PE=1 SV=2 8.75 3558.4 - 1.25E+06 - - - 0.1981 - 1.451 0.228 - 119.9 1 2 0 0.0002 7 0 0 0 1.25E+07 9.09E+06 - - - 1.9045 0.9896 230117_WJC_METTL3_WT_vs_EV_F04.18349.18349.2 0.136 20-Sep R.LPPEFSPVIIK[136.11].E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1246.7417 0.21 32602 18349 2 1246.743456 624.3781 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6 3558.5 - 1.01E+06 - - - 1.4398 - 1.384 0.071 - 193.5 1 2 0 0.0018 11 0 0 0 1.71E+06 8.15E+06 - - - 0.444 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18350.18350.2 0.00338 16-Oct K.LEVDIPLVK.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1024.6168 2.38 32603 18350 2 1024.61815 513.3157 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3558.6 - 862154 - - - 1.2707 - 1.852 0.428 - 297.4 1 2 0 0.0013 9 0 0 0 8.57E+07 3.60E+07 - - - 3.9847 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18352.18352.2 0.0133 20-Sep R.ILMLGLDAAGK[136.11].T sp|P62330|ARF6_HUMAN 1 1108.6406 0.92 32605 18352 2 1108.641016 555.3276 ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2 5.84 3558.9 - 809782 - - - 0.405 - 1.79 0.414 - 153.6 1 2 0 0.0004 11 0 0 0 4.78E+06 5.20E+06 - - - 3.6737 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.18356.18356.2 0.0384 14-Sep R.EMVLEIIR[166.11].E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1011.5662 1.35 32607 18356 2 1011.567497 506.7904 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3559.4 - 1.51E+06 - - - 1.2594 - 1.961 0.22 - 426.7 1 2 0 0.0013 8 0 0 0 2.21E+08 1.63E+08 - - - 2.6966 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.18358.18358.2 0.0613 16-Aug K.ILLITEDLK.N sp|Q08752|PPID_HUMAN 1 1056.6431 2.94 32609 18358 2 1056.64603 529.3288 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 4.37 3559.7 - 652520 - - - 2.8079 - 1.754 0.251 - 175.1 1 2 0 0.003 9 0 0 0 1.96E+07 6.66E+06 - - - 2.5196 0.9869 230117_WJC_METTL3_WT_vs_EV_F04.18363.18363.2 0.226 16-Jun R.LLYGMALVR[166.11].F "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3R6|A0A7I2V3R6_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V4V0|A0A7I2V4V0_HUMAN,tr|A0A7I2V5R7|A0A7I2V5R7_HUMAN,tr|A0A7I2V653|A0A7I2V653_HUMAN,tr|A0A7I2YQI7|A0A7I2YQI7_HUMAN" 7 1044.6029 1.31 32614 18363 2 1044.606526 523.3087 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 8.75 3560.3 - 197972 - - - 3.431 - 1.342 0.166 - 74.2 3 2 0 0.0036 9 0 0 0 9.15E+06 6.97E+06 - - - 0.9038 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.18370.18370.2 0.205 14-Aug K.VALLLLEK.E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 897.5899 1.3 32619 18370 2 897.590764 449.8022 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3561.1 - 3.82E+06 - - - 0.957 - 1.75 0.243 - 217.6 1 2 0 0.0009 8 0 0 0 1.56E+07 1.21E+07 - - - 2.5233 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18371.18371.2 0.000107 22-Oct K.GLTPSQIGVILR[166.11].D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1262.7586 0.89 32620 18371 2 1262.759685 632.3866 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3561.1 - 5.00E+06 - - - 0.8656 - 2.14 0.318 - 412.6 1 2 0 0.0011 12 0 0 0 3.66E+07 4.13E+07 - - - 3.3912 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18372.18372.2 9.51E-06 22-Nov K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 0.89 32621 18372 2 1252.751201 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3561.1 - 3.81E+06 - - - 0.7017 - 2.273 0.316 - 510 1 2 0 0.0009 12 0 0 0 3.66E+07 4.13E+07 - - - 3.5352 0.9927 230117_WJC_METTL3_WT_vs_EV_F04.18373.18373.2 1.26 12-Jul R.FQLQLLR.E sp|Q9P2R3|ANFY1_HUMAN 1 916.5494 0.64 32622 18373 2 916.551105 459.282 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 9.75 3561.2 - 2.02E+06 - - - 1.8199 - 1.25 0.134 - 199.9 1 2 0 0.0017 7 0 0 0 7.54E+06 1.18E+07 - - - 0.7372 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.18378.18378.2 0.00294 20-Nov R.YFGPNLLNTVK[136.11].Q "sp|P62487|RPB7_HUMAN,tr|E9PIU7|E9PIU7_HUMAN,tr|E9PKH3|E9PKH3_HUMAN,tr|H0YEE4|H0YEE4_HUMAN" 4 1272.6958 0.84 32627 18378 2 1272.695933 637.3552 DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1 8.59 3561.7 - 685359 - - - 0.1257 - 1.72 0.379 - 311 1 2 0 0.0002 11 0 0 0 2.84E+06 3.40E+06 - - - 3.3074 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18379.18379.2 0.0066 18-Sep K.ALQEFDLALR.G "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1174.6346 0.54 32628 18379 2 1174.636248 588.3246 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 4.37 3561.9 - 539997 - - - 1.3834 - 1.923 0.373 - 246.6 1 2 0 0.0016 10 0 0 0 5.86E+06 1.08E+07 - - - 3.6207 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.18382.18382.2 0.0175 14-Sep K.VALLLLEK[136.11].E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 905.6041 1.3 32630 18382 2 905.604972 453.8093 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3562.2 - 483773 - - - 0.9574 - 2.148 0.083 - 288.9 1 2 0 0.0009 8 0 0 0 1.57E+07 1.21E+07 - - - 1.9596 0.9952 230117_WJC_METTL3_WT_vs_EV_F04.18386.18386.2 0.03 12-Jun R.EIFITFR.V sp|Q96EY1|DNJA3_HUMAN 1 924.5069 1.75 32633 18386 2 924.509994 463.2607 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.1 3562.7 - 1.44E+06 - - - 3.3434 - 1.359 0.243 - 110.1 2 2 0 0.0031 7 0 0 0 1.87E+07 1.07E+07 - - - 1.6723 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18387.18387.2 0.0125 16-Nov R.LYSVSYLLK[136.11].D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1092.631 0.75 32634 18387 2 1092.633624 547.3228 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.5 3562.8 - 1.43E+06 - - - 2.3576 - 2.042 0.445 - 335.4 1 2 0 0.0026 9 0 0 0 2.59E+07 3.47E+07 - - - 4.3924 1 230117_WJC_METTL3_WT_vs_EV_F04.18388.18388.2 6.50E-05 16-Nov K.LYMVLITTK.N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 3 1080.6253 1.5 32635 18388 2 1080.628523 541.3199 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 8.59 3563 - 1.35E+06 - - - 2.9788 - 1.988 0.488 - 450.6 1 2 0 0.0032 9 0 0 0 1.10E+07 7.37E+06 - - - 4.6323 1 230117_WJC_METTL3_WT_vs_EV_F04.18389.18389.2 7.68E-07 13/22 K.AFAVGVQQVLLK.V sp|O95373|IPO7_HUMAN 1 1271.7602 1.69 32636 18389 2 1271.761897 636.8874 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 8.8 3563.1 - 541818 - - - 1.3674 - 2.679 0.599 - 524.8 1 2 0 0.0017 12 0 0 0 1.10E+07 6.52E+06 - - - 6.0575 1 230117_WJC_METTL3_WT_vs_EV_F04.18392.18392.2 5.40E-05 13/22 K.AFAVGVQQVLLK[136.11].V sp|O95373|IPO7_HUMAN 1 1279.7744 1.69 32639 18392 2 1279.777697 640.8945 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 8.8 3563.5 - 297216 - - - 2.6091 - 2.615 0.575 - 561.1 1 2 0 0.0033 12 0 0 0 1.10E+07 6.52E+06 - - - 5.8162 0.996 230117_WJC_METTL3_WT_vs_EV_F04.18396.18396.2 0.623 14-Jul R.EMVLEIIR.E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1001.558 1.35 32642 18396 2 1001.560713 501.7863 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3564 - 8.69E+06 - - - 2.7557 - 1.545 0.158 - 293.7 1 2 0 0.0028 8 0 0 0 2.21E+08 1.63E+08 - - - 1.5191 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.18399.18399.2 0.0277 12-Jul R.EIFITFR[166.11].V sp|Q96EY1|DNJA3_HUMAN 1 934.5152 1.75 32644 18399 2 934.516409 468.2649 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.1 3564.3 - 1.49E+06 - - - 1.3226 - 1.637 0.274 - 185.4 1 2 0 0.0012 7 0 0 0 1.86E+07 1.06E+07 - - - 2.626 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18400.18400.2 0.0046 16-Nov R.SLIAEVLVK.L sp|O95969|SG1D2_HUMAN 1 970.6063 253.68 32645 18400 2 970.608767 486.3104 Secretoglobin family 1D member 2 OS=Homo sapiens OX=9606 GN=SCGB1D2 PE=2 SV=1 5.72 3564.4 - 1.96E+06 - - - 2.5592 - 1.879 0.356 - 367.9 1 2 0 0.0025 9 0 0 0 1.62E+07 6.37E+04 - - - 3.4944 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18403.18403.2 7.56E-05 18-Aug K.VFLSGMPELR.L "sp|Q9Y6Q5|AP1M2_HUMAN,sp|Q9BXS5|AP1M1_HUMAN,tr|E7ENJ6|E7ENJ6_HUMAN,tr|K7EJL1|K7EJL1_HUMAN,tr|K7EJJ1|K7EJJ1_HUMAN,tr|K7EMG5|K7EMG5_HUMAN,tr|K7EPR4|K7EPR4_HUMAN" 7 1147.606 1.14 32648 18403 2 1147.608689 574.8103 AP-1 complex subunit mu-2 OS=Homo sapiens OX=9606 GN=AP1M2 PE=1 SV=4 5.97 3564.7 - 594697 - - - 2.3736 - 1.767 0.475 - 225.8 1 2 0 0.0027 10 0 0 0 5.76E+06 5.07E+06 - - - 4.1375 0.9958 230117_WJC_METTL3_WT_vs_EV_F04.18404.18404.2 0.98 12-Jun R.DLFALAR[166.11].K sp|Q9Y4W6|AFG32_HUMAN 1 814.4577 1.35 32649 18404 2 814.458933 408.2361 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.84 3564.9 - 425791 - - - 1.5655 - 1.178 0.21 - 172.5 1 2 0 0.0013 7 0 0 0 8.33E+06 6.18E+06 - - - 1.1107 1 230117_WJC_METTL3_WT_vs_EV_F04.18409.18409.2 0.000341 13/22 R.MGLAISLVATEK.E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 1231.6846 1.48 32653 18409 2 1231.688085 616.8496 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.75 3565.5 - 1.39E+06 - - - 2.8213 - 2.682 0.534 - 615.6 1 2 0 0.0035 12 0 0 0 2.38E+07 1.60E+07 - - - 5.5798 1 230117_WJC_METTL3_WT_vs_EV_F04.18411.18411.2 4.56E-06 22-Dec R.MGLAISLVATEK[136.11].E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 1239.6988 1.48 32655 18411 2 1239.697653 620.8567 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.75 3565.7 - 1.17E+06 - - - -0.9333 - 2.572 0.489 - 396.8 1 2 0 -0.0012 12 0 0 0 2.38E+07 1.60E+07 - - - 5.138 0.9938 230117_WJC_METTL3_WT_vs_EV_F04.18413.18413.2 1.15 12-Jul R.DLFALAR.K sp|Q9Y4W6|AFG32_HUMAN 1 804.4494 1.35 32657 18413 2 804.451817 403.232 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.84 3565.9 - 636602 - - - 3.0195 - 1.311 0.188 - 228.4 1 2 0 0.0024 7 0 0 0 8.33E+06 6.18E+06 - - - 1.2868 0.999 230117_WJC_METTL3_WT_vs_EV_F04.18414.18414.2 0.0064 14-Sep K.NGLDVLFK.V "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 904.5018 1.41 32658 18414 2 904.504842 453.2582 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 5.84 3566.1 - 630717 - - - 3.3433 - 1.794 0.364 - 251.4 1 2 0 0.003 8 0 0 0 5.88E+06 4.16E+06 - - - 3.4912 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18416.18416.2 0.000441 20-Sep K.LVNIYDSMPLR[166.11].Y sp|Q9UBQ6|EXTL2_HUMAN 1 1329.699 0.69 32660 18416 2 1329.702039 665.8568 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 5.84 3566.3 - 242847 - - - 2.2644 - 1.89 0.39 - 339.4 1 2 0 0.003 11 0 0 0 1.23E+06 1.79E+06 - - - 3.6427 1 230117_WJC_METTL3_WT_vs_EV_F04.18417.18417.2 1.47E-06 20-Sep K.LVNIYDSMPLR.Y sp|Q9UBQ6|EXTL2_HUMAN 1 1319.6908 0.69 32661 18417 2 1319.69329 660.8527 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 5.84 3566.5 - 235550 - - - 1.9186 - 2.319 0.532 - 336.9 1 2 0 0.0025 11 0 0 0 1.23E+06 1.79E+06 - - - 5.245 0.9755 230117_WJC_METTL3_WT_vs_EV_F04.18418.18418.2 0.00756 18-Sep R.LLDEQFAVLR.G sp|O75146|HIP1R_HUMAN 1 1202.6659 0.38 32662 18418 2 1202.675382 602.3402 Huntingtin-interacting protein 1-related protein OS=Homo sapiens OX=9606 GN=HIP1R PE=1 SV=2 4.37 3566.6 - 161917 - - - 7.865 - 1.711 0.324 - 176.2 1 2 0 0.0095 10 0 0 0 2.10E+06 5.54E+06 - - - 2.9302 0.9742 230117_WJC_METTL3_WT_vs_EV_F04.18426.18426.2 0.0171 12-Jul K.DFISVLR[166.11].G sp|Q9Y3B9|RRP15_HUMAN 1 858.4839 0.94 32669 18426 2 858.485823 430.2492 RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2 5.84 3567.5 - 1.78E+06 - - - 2.2714 - 1.334 0.002 - 230.1 1 2 0 0.0019 7 0 0 0 1.66E+07 1.77E+07 - - - -0.0317 0.9969 230117_WJC_METTL3_WT_vs_EV_F04.18428.18428.2 0.142 12-Jul R.NYLSIFR.K sp|P07384|CAN1_HUMAN 1 911.4865 4.51 32671 18428 2 911.488516 456.7505 Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1 8.75 3567.8 - 924004 - - - 2.2096 - 1.34 0.206 - 197.8 1 2 0 0.002 7 0 0 0 6.29E+06 1.40E+06 - - - 1.4892 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.18429.18429.2 0.508 18-Dec K.ALQEFDLALR[166.11].G "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1184.6429 0.67 32672 18429 2 1184.645471 593.3287 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 4.37 3567.9 - 716491 - - - 2.1762 - 1.911 0.255 - 523.6 1 2 0 0.0026 10 0 0 0 5.60E+06 8.36E+06 - - - 2.7313 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18430.18430.2 4.40E-05 18-Sep R.VLLMELEEAR.G sp|P12270|TPR_HUMAN 1 1201.6377 1.38 32673 18430 2 1201.640908 601.8261 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3568 - 527233 - - - 2.703 - 2.239 0.339 - 284.3 1 2 0 0.0032 10 0 0 0 2.36E+07 1.70E+07 - - - 3.7937 0.9858 230117_WJC_METTL3_WT_vs_EV_F04.18441.18441.2 1.47 18-Aug K.FYALDPSFPR.M sp|Q08J23|NSUN2_HUMAN 1 1211.5975 1.51 32683 18441 2 1211.599676 606.806 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3569.4 - 420627 - - - 1.7885 - 1.123 0.122 - 178.4 1 2 0 0.0022 10 0 0 0 1.92E+07 1.27E+07 - - - 0.2652 0.9877 230117_WJC_METTL3_WT_vs_EV_F04.18445.18445.2 0.119 14-Jul K.SIGDIFLK.Y "sp|Q9H8V3|ECT2_HUMAN,tr|H7C3G1|H7C3G1_HUMAN" 2 891.5066 0.88 32686 18445 2 891.510441 446.7606 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 5.55 3569.9 - 1.34E+06 - - - 4.3432 - 1.212 0.246 - 129.2 1 2 0 0.0039 8 0 0 0 1.25E+07 1.43E+07 - - - 1.4366 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.18446.18446.2 0.0568 16-Oct K.LLQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1118.5748 12.7 32687 18446 2 1118.578954 560.2947 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3570 - 959709 - - - 3.702 - 1.917 0.334 - 316.5 1 2 0 0.0041 9 0 0 0 2.96E+08 2.33E+07 - - - 3.3893 0.998 230117_WJC_METTL3_WT_vs_EV_F04.18447.18447.2 0.00259 16-Sep R.ELGELIPLR.Q "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1038.6073 1.2 32688 18447 2 1038.611614 520.3109 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.53 3570.1 - 616649 - - - 4.1093 - 1.742 0.336 - 227.9 1 2 0 0.0043 9 0 0 0 1.06E+07 8.80E+06 - - - 3.1271 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.18450.18450.2 0.00113 18-Sep K.TLVQILTEPR[166.11].N sp|O76031|CLPX_HUMAN 1 1178.6898 2.09 32691 18450 2 1178.695085 590.3522 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3570.5 - 271914 - - - 4.4473 - 2.232 0.435 - 245.6 1 2 0 0.0052 10 0 0 0 6.71E+06 3.21E+06 - - - 4.4934 0.983 230117_WJC_METTL3_WT_vs_EV_F04.18455.18455.2 0.0687 14-Jul K.SIGDIFLK[136.11].Y "sp|Q9H8V3|ECT2_HUMAN,tr|H7C3G1|H7C3G1_HUMAN" 2 899.5208 0.94 32695 18455 2 899.524743 450.7677 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 5.55 3571.2 - 2.33E+06 - - - 4.4179 - 1.157 0.235 - 126.1 1 2 0 0.004 8 0 0 0 1.20E+07 1.28E+07 - - - 1.2153 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.18457.18457.2 0.0649 12-Aug K.C[160.03]ALDFFR.Q sp|P51970|NDUA8_HUMAN 1 927.4273 1.4 32696 18457 2 927.430557 464.7209 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3571.4 - 608332 - - - 3.541 - 1.647 0.296 - 261 1 2 0 0.0033 7 0 0 0 1.64E+07 1.17E+07 - - - 2.8072 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.18458.18458.2 0.0236 12-Oct K.C[160.03]ALDFFR[166.11].Q sp|P51970|NDUA8_HUMAN 1 937.4355 1.4 32697 18458 2 937.439559 469.725 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3571.5 - 598985 - - - 4.284 - 1.853 0.369 - 455.3 1 2 0 0.004 7 0 0 0 1.64E+07 1.17E+07 - - - 3.7196 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.18459.18459.2 0.0034 16-Aug R.ILFLDPSGK.V sp|O95881|TXD12_HUMAN 1 988.5593 1.09 32698 18459 2 988.564817 495.2869 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3571.6 - 2.04E+07 - - - 5.5475 - 1.684 0.408 - 179.9 1 2 0 0.0055 9 0 0 0 4.99E+08 4.56E+08 - - - 3.5605 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.18460.18460.2 0.0154 16-Sep K.LQDPFSLYR.C sp|P21912|SDHB_HUMAN 1 1137.5819 2.78 32699 18460 2 1137.585337 569.7982 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.84 3571.7 - 414846 - - - 3.0574 - 2.002 0.302 - 168.3 1 2 0 0.0035 9 0 0 0 3.00E+07 1.08E+07 - - - 3.2787 0.9683 230117_WJC_METTL3_WT_vs_EV_F04.18462.18462.2 0.0222 20-Jul R.LPPEFSPVIIK.E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1238.7275 0.46 32701 18462 2 1238.736525 620.371 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6 3571.9 - 249099 - - - 7.3172 - 1.566 0.282 - 78.9 1 2 0 0.0091 11 0 0 0 5.09E+06 1.10E+07 - - - 2.3344 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18467.18467.2 0.000313 24-Oct K.LFPDTPLALDANK[136.11].K sp|Q12906|ILF3_HUMAN 1 1421.7646 0.66 32706 18467 2 1421.768398 711.8896 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3572.6 - 101369 - - - 2.6847 - 2.065 0.443 - 282.8 1 2 0 0.0038 13 0 0 0 7.38E+06 1.12E+07 - - - 4.1729 0.9941 230117_WJC_METTL3_WT_vs_EV_F04.18471.18471.2 0.00689 18-Aug K.FLALYLHGAA.- "sp|Q9BZE1|RM37_HUMAN,tr|A6NHR2|A6NHR2_HUMAN" 2 1074.5862 - 32708 18471 2 1074.590627 538.3004 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 6.74 3573.2 - 2.58E+06 - - - 4.1048 - 1.365 0.275 - 147 1 2 0 0.0044 10 0 0 0 - - - - - 1.9393 0.9658 230117_WJC_METTL3_WT_vs_EV_F04.18479.18479.2 0.0186 16-Sep R.GFIVESVLR.N sp|Q86UQ0|ZN589_HUMAN 1 1018.5811 2.33 32716 18479 2 1018.589035 510.2978 Zinc finger protein 589 OS=Homo sapiens OX=9606 GN=ZNF589 PE=1 SV=1 6 3574.1 - 503252 - - - 7.7598 - 2.022 0.19 - 239.6 1 2 0 0.0079 9 0 0 0 3.48E+06 1.49E+06 - - - 2.4788 0.9962 230117_WJC_METTL3_WT_vs_EV_F04.18480.18480.2 0.038 16-Nov K.LALFQAIGK.E "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 959.5804 1.55 32717 18480 2 959.585962 480.7975 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 8.75 3574.3 - 501349 - - - 5.7932 - 2.135 0.373 - 264.7 1 2 0 0.0056 9 0 0 0 3.47E+06 2.25E+06 - - - 3.9885 0.9785 230117_WJC_METTL3_WT_vs_EV_F04.18482.18482.2 0.0371 12-Jun R.TIFSYFK.G sp|Q9UJV9|DDX41_HUMAN 1 904.4695 1.06 32719 18482 2 904.47369 453.242 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 8.26 3574.5 - 339754 - - - 4.6823 - 1.2 0.21 - 112.4 1 2 0 0.0042 7 0 0 0 2.20E+07 2.08E+07 - - - 1.1684 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.18485.18485.2 1.88E-05 18-Nov K.LGMNLMNELK.Q "sp|Q16890|TPD53_HUMAN,tr|E9PNK6|E9PNK6_HUMAN,tr|E9PNQ9|E9PNQ9_HUMAN,tr|E9PPQ1|E9PPQ1_HUMAN,tr|J3KNE7|J3KNE7_HUMAN" 5 1161.5886 1.69 32722 18485 2 1161.594516 581.8016 Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1 6 3574.9 - 208046 - - - 5.0922 - 2.237 0.396 - 261.1 1 2 0 0.0059 10 0 0 0 2.72E+06 1.61E+06 - - - 4.2114 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.18486.18486.2 5.52E-05 24-Dec K.LFPDTPLALDANK.K sp|Q12906|ILF3_HUMAN 1 1413.7504 0.63 32723 18486 2 1413.756651 707.8825 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3575.1 - 203620 - - - 4.435 - 1.894 0.464 - 490.2 1 2 0 0.0063 13 0 0 0 5.57E+06 8.88E+06 - - - 4.1054 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.18487.18487.2 0.0084 22-Sep K.LLYAFAEATVPK.V "sp|P05166|PCCB_HUMAN,tr|E9PEC3|E9PEC3_HUMAN,tr|E7ETT1|E7ETT1_HUMAN,tr|E7ETT4|E7ETT4_HUMAN,tr|E9PDR0|E9PDR0_HUMAN,tr|C9JQS9|C9JQS9_HUMAN,tr|E7EX59|E7EX59_HUMAN,tr|E7EUY3|E7EUY3_HUMAN" 8 1321.7282 0.67 32724 18487 2 1321.733909 661.8714 "Propionyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=PCCB PE=1 SV=3" 6 3575.2 - 170880 - - - 4.3277 - 2.032 0.247 - 213.4 1 2 0 0.0057 12 0 0 0 1.62E+06 2.40E+06 - - - 2.7291 0.9972 230117_WJC_METTL3_WT_vs_EV_F04.18501.18501.2 0.176 18-Sep R.LGLLGLPAPK.N sp|Q99459|CDC5L_HUMAN 1 977.6274 1.17 32736 18501 2 977.630635 489.821 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3577 - 243063 - - - 3.3571 - 2.064 0.152 - 190.8 1 2 0 0.0033 10 0 0 0 7.38E+07 6.31E+07 - - - 2.1853 0.9498 230117_WJC_METTL3_WT_vs_EV_F04.18502.18502.2 0.982 12-Jun K.LIPFLEK[136.11].L sp|Q05D32|CTSL2_HUMAN 1 866.5357 1.06 32737 18502 2 866.538248 434.2751 CTD small phosphatase-like protein 2 OS=Homo sapiens OX=9606 GN=CTDSPL2 PE=1 SV=2 6 3577.1 - 201367 - - - 2.9508 - 1.188 0.024 - 90.1 1 2 0 0.0026 7 0 0 0 2.26E+06 2.14E+06 - - - -0.2367 0.9868 230117_WJC_METTL3_WT_vs_EV_F04.18505.18505.2 8.16 12-Jul K.EVILPIK.V sp|Q4G0P3|HYDIN_HUMAN 1 810.5215 1.44 32740 18505 2 810.522983 406.268 Hydrocephalus-inducing protein homolog OS=Homo sapiens OX=9606 GN=HYDIN PE=1 SV=3 6.1 3577.5 - 99110.1 - - - 1.8408 - 1.437 0.018 - 211 1 2 0 0.0015 7 0 0 0 1.29E+07 8.93E+06 - - - 0.3223 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.18508.18508.2 0.00567 16-Nov K.LLQDFFNGR.D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1108.5665 11.28 32742 18508 2 1108.570887 555.2905 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3577.9 - 1.64E+07 - - - 3.9186 - 2.095 0.457 - 461.1 1 2 0 0.0043 9 0 0 0 2.97E+08 2.63E+07 - - - 4.5546 0.999 230117_WJC_METTL3_WT_vs_EV_F04.18510.18510.2 0.00885 14-Sep R.LLLEEIYR[166.11].G "sp|Q9Y2P8|RCL1_HUMAN,tr|Q5VZU2|Q5VZU2_HUMAN,tr|Q5VZU3|Q5VZU3_HUMAN" 3 1057.6047 0.66 32744 18510 2 1057.608698 529.8096 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 4.53 3578 - 1.09E+06 - - - 3.7642 - 1.989 0.385 - 296.9 1 2 0 0.004 8 0 0 0 9.65E+06 1.46E+07 - - - 3.9572 1 230117_WJC_METTL3_WT_vs_EV_F04.18511.18511.2 7.26E-06 18-Dec K.TLVQILTEPR.N sp|O76031|CLPX_HUMAN 1 1168.6816 2.5 32745 18511 2 1168.685439 585.3481 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3578.2 - 525606 - - - 3.308 - 2.228 0.454 - 627.7 1 2 0 0.0039 10 0 0 0 6.38E+06 2.56E+06 - - - 4.6292 0.9696 230117_WJC_METTL3_WT_vs_EV_F04.18516.18516.2 1.44 12-Jul K.DLLLPIK[136.11].T "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 3 818.5357 1.44 32750 18516 2 818.537276 410.2751 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 5.84 3578.8 - 226296 - - - 1.9364 - 1.26 0.001 - 204.1 1 2 0 0.0016 7 0 0 0 1.29E+07 8.93E+06 - - - -0.2198 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.18524.18524.2 0.00788 18-Nov R.LGLLGLPAPK[136.11].N sp|Q99459|CDC5L_HUMAN 1 985.6416 1.15 32757 18524 2 985.645201 493.8281 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3579.8 - 2.70E+06 - - - 3.7011 - 2.111 0.218 - 238.5 1 2 0 0.0036 10 0 0 0 7.23E+07 6.26E+07 - - - 2.7356 1 230117_WJC_METTL3_WT_vs_EV_F04.18525.18525.2 2.42E-07 20-Nov K.LGLENAEALIR.L sp|P10155|RO60_HUMAN 1 1197.6717 3.31 32758 18525 2 1197.675833 599.8431 60 kDa SS-A\Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2 4.53 3580 - 2.17E+06 - - - 3.42 - 2.756 0.415 - 343.8 1 2 0 0.0041 11 0 0 0 2.76E+07 8.35E+06 - - - 4.8474 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18526.18526.2 0.00758 22-Dec K.YILAATLDNTLK[136.11].L sp|P61964|WDR5_HUMAN 1 1342.7588 1.34 32759 18526 2 1342.762164 672.3867 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 5.83 3580.1 - 1.30E+06 - - - 2.5291 - 2.125 0.434 - 359.6 1 2 0 0.0034 12 0 0 0 1.81E+07 1.35E+07 - - - 4.2288 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.18527.18527.2 2.73 20-Aug R.ILILGLDGAGK[136.11].T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1076.6685 4.22 32760 18527 2 1076.672964 539.3415 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 3580.2 - 1.20E+06 - - - 4.1498 - 1.744 0.271 - 116.5 1 2 0 0.0045 11 0 0 0 2.21E+07 5.23E+06 - - - 2.5458 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.18528.18528.2 5.76E-05 13/20 K.LGLENAEALIR[166.11].L sp|P10155|RO60_HUMAN 1 1207.68 3.3 32761 18528 2 1207.68659 604.8473 60 kDa SS-A\Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2 4.53 3580.4 - 970208 - - - 5.4509 - 2.322 0.432 - 428.9 1 2 0 0.0066 11 0 0 0 2.24E+07 6.79E+06 - - - 4.5087 1 230117_WJC_METTL3_WT_vs_EV_F04.18529.18529.2 5.26E-06 19/28 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 1.42 32762 18529 2 1458.761974 730.386 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3580.5 - 878510 - - - 3.0965 - 3.832 0.598 - 1463 1 2 0 0.0045 15 0 0 0 1.05E+08 7.41E+07 - - - 6.7592 0.9962 230117_WJC_METTL3_WT_vs_EV_F04.18530.18530.2 0.00591 12-Jul R.VWSDFLR.V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 921.4709 2.4 32763 18530 2 921.474479 461.7427 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.81 3580.6 - 846897 - - - 3.9361 - 1.472 0.271 - 251.9 1 2 0 0.0036 7 0 0 0 1.02E+07 4.25E+06 - - - 2.2665 1 230117_WJC_METTL3_WT_vs_EV_F04.18531.18531.2 2.37E-05 20/28 R.LPAAGVGDMVMATVK[136.11].K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1466.7717 1.42 32764 18531 2 1466.773629 734.3931 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3580.7 - 665177 - - - 1.3444 - 3.853 0.56 - 1560.8 1 2 0 0.002 15 0 0 0 1.05E+08 7.41E+07 - - - 6.4928 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18533.18533.2 9.81E-05 20-Aug K.VIAEDEVLWYR.L "sp|Q8N3Y1|FBXW8_HUMAN,tr|A0A499FIY5|A0A499FIY5_HUMAN" 2 1391.7085 25.8 32766 18533 2 1391.709773 696.8615 F-box\WD repeat-containing protein 8 OS=Homo sapiens OX=9606 GN=FBXW8 PE=1 SV=2 4.14 3581 - 98270.5 - - - 0.9032 - 1.924 0.459 - 177.6 1 2 0 0.0013 11 0 0 0 1.94E+06 7.53E+04 - - - 4.2011 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.18542.18542.2 0.526 12-Jun R.LFLEFER.K "sp|O43663|PRC1_HUMAN,sp|Q96I25|SPF45_HUMAN,tr|H0YL53|H0YL53_HUMAN" 3 952.5018 2.38 32773 18542 2 952.503635 477.2582 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 3582.1 - 1.39E+06 - - - 1.9076 - 1.345 0.182 - 154.9 1 2 0 0.0018 7 0 0 0 1.76E+07 7.40E+06 - - - 1.3238 1 230117_WJC_METTL3_WT_vs_EV_F04.18543.18543.2 5.81E-06 13/20 R.LYEAYLPETFR.R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1400.6976 2.34 32774 18543 2 1400.702103 701.3561 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3582.2 - 1.08E+06 - - - 3.2027 - 2.506 0.533 - 695 1 2 0 0.0045 11 0 0 0 3.76E+07 1.60E+07 - - - 5.4616 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18544.18544.3 2.29E-05 17/56 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 1.48 32775 18544 3 1458.764076 487.2598 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3582.3 - 985595 - - - 4.5374 - 2.93 0.393 - 419.4 1 2 0 0.0066 15 0 0 0 3.20E+07 2.16E+07 - - - 5.7248 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.18545.18545.2 0.00178 20-Dec R.LYEAYLPETFR[166.11].R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1410.7059 2.34 32776 18545 2 1410.711725 706.3602 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3582.4 - 674816 - - - 4.1384 - 2.017 0.457 - 206.1 1 2 0 0.0058 11 0 0 0 3.76E+07 1.60E+07 - - - 4.3126 0.998 230117_WJC_METTL3_WT_vs_EV_F04.18546.18546.2 0.0176 12-Jun R.VWSDFLR[166.11].V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 931.4791 2.41 32777 18546 2 931.481565 466.7468 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.81 3582.6 - 643757 - - - 2.6227 - 1.334 0.288 - 139.6 1 2 0 0.0024 7 0 0 0 1.01E+07 4.19E+06 - - - 2.0805 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.18548.18548.2 0.0323 20-Nov R.FLSAEAIGIMR[166.11].R sp|Q16512|PKN1_HUMAN 1 1216.6513 2.6 32779 18548 2 1216.654529 609.333 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 6 3582.8 - 423293 - - - 2.6137 - 2.003 0.269 - 258.4 1 2 0 0.0032 11 0 0 0 8.26E+06 3.18E+06 - - - 2.906 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.18550.18550.2 0.0147 14-Jul R.WVVPVLPK.G "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 936.5797 2.39 32781 18550 2 936.581682 469.2971 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3583.1 - 213406 - - - 2.144 - 1.568 0.341 - 149.8 1 2 0 0.002 8 0 0 0 8.16E+06 3.42E+06 - - - 2.9156 1 230117_WJC_METTL3_WT_vs_EV_F04.18552.18552.2 0.000576 20-Dec K.LALDMEIATYR.K "sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|Q14CN4|K2C72_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 4 1294.6591 99.96 32783 18552 2 1294.658399 648.3368 "Keratin, type II cytoskeletal 74 OS=Homo sapiens OX=9606 GN=KRT74 PE=1 SV=2" 4.37 3583.3 - 163720 - - - -0.5592 - 2.622 0.481 - 712.6 1 2 0 -0.0007 11 0 0 0 3.61E+06 3.61E+04 - - - 5.2011 1 230117_WJC_METTL3_WT_vs_EV_F04.18558.18558.2 0.00138 22-Dec K.YILAATLDNTLK.L sp|P61964|WDR5_HUMAN 1 1334.7446 1.34 32788 18558 2 1334.748423 668.3796 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 5.83 3584.1 - 2.21E+06 - - - 2.8882 - 2.449 0.485 - 377 1 2 0 0.0039 12 0 0 0 1.81E+07 1.35E+07 - - - 4.9787 1 230117_WJC_METTL3_WT_vs_EV_F04.18560.18560.2 8.09E-07 18/30 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 17.34 32790 18560 2 1686.899958 844.4543 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3584.3 - 2.56E+06 - - - 3.4815 - 3.343 0.583 - 897.3 1 2 0 0.0059 16 0 0 0 5.85E+07 3.37E+06 - - - 6.3123 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.18561.18561.2 0.933 14-Aug K.MDELQLFR[166.11].G "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0T971|A0A7P0T971_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7P0Z4D1|A0A7P0Z4D1_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0T946|A0A7P0T946_HUMAN,tr|A0A7P0TBK7|A0A7P0TBK7_HUMAN" 14 1060.5251 1.15 32791 18561 2 1060.52979 531.2698 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.37 3584.4 - 2.41E+06 - - - 4.4355 - 1.987 0.269 - 336.7 1 2 0 0.0047 8 0 0 0 1.37E+07 1.19E+07 - - - 3.0972 0.995 230117_WJC_METTL3_WT_vs_EV_F04.18563.18563.2 0.00137 14-Oct K.YLELLGYR[166.11].K "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 7 1035.5629 1.53 32793 18563 2 1035.567295 518.7887 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6 3584.6 - 1.32E+06 - - - 4.2904 - 1.907 0.168 - 385.1 1 2 0 0.0044 8 0 0 0 9.79E+06 6.41E+06 - - - 2.2273 0.9012 230117_WJC_METTL3_WT_vs_EV_F04.18567.18567.2 4.75 12-Jun R.LFLEFER[166.11].K "sp|O43663|PRC1_HUMAN,sp|Q96I25|SPF45_HUMAN,tr|H0YL53|H0YL53_HUMAN" 3 962.5101 2.5 32797 18567 2 962.515205 482.2623 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 3585.1 - 932945 - - - 5.3163 - 1.309 0.058 - 107.4 1 2 0 0.0051 7 0 0 0 1.70E+07 6.79E+06 - - - 0.321 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18568.18568.2 5.11E-05 20-Oct R.IFVFEPPPGVK.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 1228.6856 2.12 32798 18568 2 1228.689836 615.3501 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3585.2 - 598793 - - - 3.4508 - 1.934 0.507 - 299.8 1 2 0 0.0042 11 0 0 0 4.34E+07 2.04E+07 - - - 4.5687 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.18569.18569.2 0.117 14-Sep R.EALAFIIR[166.11].S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 941.5574 1.12 32799 18569 2 941.560624 471.786 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3585.3 - 592023 - - - 3.4539 - 1.861 0.234 - 294.6 1 2 0 0.0033 8 0 0 0 2.00E+07 1.78E+07 - - - 2.6416 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.18571.18571.2 0.00013 22-Nov K.GGIVGMTLPIAR.D "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 1183.6747 1.48 32801 18571 2 1183.679596 592.8446 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 9.75 3585.6 - 502933 - - - 4.1244 - 1.789 0.432 - 336 1 2 0 0.0049 12 0 0 0 1.51E+07 1.02E+07 - - - 3.7607 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.18572.18572.2 0.000461 20-Oct R.IFVFEPPPGVK[136.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 1236.6998 2.09 32802 18572 2 1236.705665 619.3572 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3585.7 - 425957 - - - 4.7457 - 1.88 0.448 - 275.4 1 2 0 0.0059 11 0 0 0 4.28E+07 2.04E+07 - - - 4.0558 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.18574.18574.2 0.159 12-Jul R.LQFLFAK.D "sp|Q7Z3K3|POGZ_HUMAN,tr|H0YCT3|H0YCT3_HUMAN" 2 865.5062 1.21 32804 18574 2 865.509434 433.7604 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 8.75 3586 - 363222 - - - 3.7654 - 1.481 0.297 - 150.1 1 2 0 0.0033 7 0 0 0 4.01E+06 3.30E+06 - - - 2.478 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.18576.18576.2 0.00792 12-Jul R.LQFLFAK[136.11].D "sp|Q7Z3K3|POGZ_HUMAN,tr|H0YCT3|H0YCT3_HUMAN" 2 873.5204 1.13 32806 18576 2 873.524424 437.7675 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 8.75 3586.2 - 264184 - - - 4.6353 - 1.767 0.322 - 141.4 1 2 0 0.004 7 0 0 0 4.03E+06 3.56E+06 - - - 3.2218 0.9844 230117_WJC_METTL3_WT_vs_EV_F04.18579.18579.2 0.111 20-Jul R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 6.12 32808 18579 2 1068.658505 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 3586.7 - 2.20E+06 - - - 3.9386 - 1.213 0.198 - 79.5 1 2 0 0.0042 11 0 0 0 1.15E+08 1.88E+07 - - - 1.0245 1 230117_WJC_METTL3_WT_vs_EV_F04.18580.18580.2 2.19E-07 18/30 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 14.91 32809 18580 2 1696.902016 849.4585 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3586.8 - 1.07E+06 - - - -0.1998 - 3.193 0.591 - 871.2 1 2 0 -0.0003 16 0 0 0 5.03E+07 3.37E+06 - - - 6.2603 1 230117_WJC_METTL3_WT_vs_EV_F04.18581.18581.3 8.26E-12 19/60 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 21.5 32810 18581 3 1686.898178 563.3053 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3586.8 - 9.46E+06 - - - 2.4264 - 3.357 0.633 - 494.6 1 2 0 0.0041 16 0 0 0 4.07E+07 1.89E+06 - - - 8.7036 1 230117_WJC_METTL3_WT_vs_EV_F04.18583.18583.2 5.44E-05 18-Nov R.EDIVVPVYLR.E "sp|P51784|UBP11_HUMAN,tr|G5E9A6|G5E9A6_HUMAN" 2 1201.6707 6.12 32812 18583 2 1201.673237 601.8426 Ubiquitin carboxyl-terminal hydrolase 11 OS=Homo sapiens OX=9606 GN=USP11 PE=1 SV=3 4.37 3586.9 - 3.41E+06 - - - 2.1329 - 2.466 0.508 - 506.4 1 2 0 0.0026 10 0 0 0 2.23E+07 3.64E+06 - - - 5.3117 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.18584.18584.2 0.00134 16-Oct R.TTLLPGLLK.T sp|Q9NSD9|SYFB_HUMAN 1 954.6114 3.17 32813 18584 2 954.613518 478.313 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 8.41 3587 - 2.18E+06 - - - 2.2522 - 1.604 0.222 - 347.6 1 2 0 0.0022 9 0 0 0 1.82E+07 5.74E+06 - - - 2.047 1 230117_WJC_METTL3_WT_vs_EV_F04.18585.18585.2 0.000458 18-Oct R.VLGLGLGC[160.03]LR.L "sp|Q9BRJ7|TIRR_HUMAN,tr|W4VSQ8|W4VSQ8_HUMAN,tr|K7EIN2|K7EIN2_HUMAN,tr|K7ENA3|K7ENA3_HUMAN" 4 1056.6114 3.41 32814 18585 2 1056.616442 529.313 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3587.1 - 1.52E+06 - - - 4.7861 - 2.27 0.484 - 320.3 1 2 0 0.0051 10 0 0 0 1.33E+07 3.91E+06 - - - 4.9025 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18586.18586.2 0.00968 18-Oct K.TNVALMC[160.03]MLR.E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1207.5876 1.18 32815 18586 2 1207.590417 604.8011 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 7.91 3587.1 - 1.39E+06 - - - 2.37 - 2.216 0.373 - 365.8 1 2 0 0.0029 10 0 0 0 4.67E+06 3.96E+06 - - - 4.0161 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.18589.18589.2 0.00537 16-Oct R.TTLLPGLLK[136.11].T sp|Q9NSD9|SYFB_HUMAN 1 962.6256 3.17 32818 18589 2 962.627773 482.3201 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 8.41 3587.4 - 926296 - - - 2.2906 - 1.536 0.254 - 251.6 1 2 0 0.0022 9 0 0 0 1.82E+07 5.74E+06 - - - 2.158 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.18590.18590.2 0.0679 16-Aug R.LFENYIELK.A sp|Q96KP1|EXOC2_HUMAN 1 1167.6176 0.94 32819 18590 2 1167.618768 584.8161 Exocyst complex component 2 OS=Homo sapiens OX=9606 GN=EXOC2 PE=1 SV=1 4.53 3587.5 - 845642 - - - 1.0209 - 1.623 0.236 - 166.1 1 2 0 0.0012 9 0 0 0 2.89E+06 3.09E+06 - - - 2.1848 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18591.18591.2 0.00165 18-Dec K.TNVALMC[160.03]MLR[166.11].E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1217.5958 1.18 32820 18591 2 1217.599347 609.8052 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 7.91 3587.7 - 792759 - - - 2.8926 - 2.032 0.439 - 642.8 1 2 0 0.0035 10 0 0 0 4.67E+06 3.96E+06 - - - 4.2614 1 230117_WJC_METTL3_WT_vs_EV_F04.18598.18598.2 3.58E-07 14/22 R.LLYMAIDGVAPR.A sp|Q9H0D6|XRN2_HUMAN 1 1317.7115 1.12 32827 18598 2 1317.711767 659.863 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3588.5 - 384655 - - - 0.2079 - 2.637 0.523 - 948.6 1 2 0 0.0003 12 0 0 0 4.51E+07 4.02E+07 - - - 5.4551 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.18601.18601.2 0.302 16-Jul R.ILFLDPSGK[136.11].V sp|O95881|TXD12_HUMAN 1 996.5735 0.97 32829 18601 2 996.576021 499.294 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3588.8 - 262322 - - - 2.4966 - 1.349 0.248 - 87.3 1 2 0 0.0025 9 0 0 0 7.00E+06 7.25E+06 - - - 1.738 1 230117_WJC_METTL3_WT_vs_EV_F04.18602.18602.2 1.20E-08 13/22 K.FGEAIGMGFPVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1251.6322 0.98 32830 18602 2 1251.635215 626.8234 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3588.8 - 6.23E+06 - - - 2.4248 - 2.457 0.577 - 606.8 1 2 0 0.003 12 0 0 0 2.04E+08 2.09E+08 - - - 5.667 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18603.18603.2 0.0862 20-Aug K.LVFLGLDNAGK.T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1145.6445 1.6 32831 18603 2 1145.645909 573.8295 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3588.9 - 4.92E+06 - - - 1.2657 - 1.818 0.377 - 210.3 1 2 0 0.0014 11 0 0 0 3.91E+08 2.44E+08 - - - 3.4421 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18604.18604.2 0.00583 20-Sep K.LVFLGLDNAGK[136.11].T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1153.6587 1.61 32832 18604 2 1153.659885 577.8366 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3588.9 - 3.47E+06 - - - 1.0627 - 1.825 0.442 - 256 1 2 0 0.0012 11 0 0 0 3.91E+08 2.44E+08 - - - 3.9326 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18605.18605.2 0.000296 16-May R.LVLDWDSVR.A "sp|Q68EM7|RHG17_HUMAN,tr|C9IZD3|C9IZD3_HUMAN,tr|I3L4P6|I3L4P6_HUMAN" 3 1101.5819 2.48 32833 18605 2 1101.583997 551.7982 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4.21 3589 - 2.98E+06 - - - 1.9408 - 1.395 0.421 - 84.6 1 2 0 0.0021 9 0 0 0 3.21E+07 1.29E+07 - - - 3.1129 1 230117_WJC_METTL3_WT_vs_EV_F04.18606.18606.2 0.000308 22-Sep R.LLYMAIDGVAPR[166.11].A sp|Q9H0D6|XRN2_HUMAN 1 1327.7198 1.12 32834 18606 2 1327.726259 664.8672 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3589 - 2.68E+06 - - - 4.8926 - 2.168 0.544 - 361.7 1 2 0 0.0065 12 0 0 0 4.51E+07 4.02E+07 - - - 5.093 0.9896 230117_WJC_METTL3_WT_vs_EV_F04.18611.18611.2 1.72 12-Jun R.GLQDVLR.T "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 799.4552 11.07 32839 18611 2 799.455743 400.7349 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.84 3589.4 - 627103 - - - 0.6767 - 1.088 0.163 - 121.9 1 2 0 0.0005 7 0 0 0 5.12E+06 4.63E+05 - - - 0.512 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.18613.18613.2 0.00231 22-Jul R.VIQEGLEGLVLK.D sp|P49916|DNLI3_HUMAN 1 1296.7653 -1 32841 18613 2 1296.769688 649.3899 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 4.53 3589.5 - 438302 - - - 3.3815 - 1.575 0.36 - 125.3 1 2 0 0.0044 12 0 0 0 0.00E+00 0.00E+00 - - - 2.8938 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.18615.18615.2 6.61E-05 26-Sep K.IFAVAATYPYQVVR.A "sp|Q9H2D1|MFTC_HUMAN,tr|A0A3B3IRK5|A0A3B3IRK5_HUMAN" 2 1596.8664 -1 32843 18615 2 1596.871706 799.4405 Mitochondrial folate transporter\carrier OS=Homo sapiens OX=9606 GN=SLC25A32 PE=1 SV=2 8.59 3589.8 - 0 - - - 3.314 - 1.849 0.432 - 170.2 1 2 0 0.0053 14 0 0 0 0.00E+00 0.00E+00 - - - 3.7725 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18617.18617.2 0.00452 14-Sep R.EALAFIIR.S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 931.5491 0.84 32844 18617 2 931.550028 466.7818 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3590.1 - 2.61E+06 - - - 0.994 - 1.868 0.29 - 349 1 2 0 0.0009 8 0 0 0 1.13E+07 1.35E+07 - - - 3.0672 0.984 230117_WJC_METTL3_WT_vs_EV_F04.18619.18619.2 0.00343 22-Dec K.GGIVGMTLPIAR[166.11].D "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 1193.683 1.48 32846 18619 2 1193.694638 597.8488 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 9.75 3590.3 - 1.28E+06 - - - 9.7631 - 2.308 0.407 - 377.4 1 2 0 0.0117 12 0 0 0 1.51E+07 1.02E+07 - - - 4.2441 0.997 230117_WJC_METTL3_WT_vs_EV_F04.18621.18621.2 0.000159 20-Dec K.NPLIINSIIDK[136.11].A "sp|Q9UNQ2|DIM1_HUMAN,tr|A0A494C0G7|A0A494C0G7_HUMAN,tr|B4DRY2|B4DRY2_HUMAN,tr|A0A7P0T8X7|A0A7P0T8X7_HUMAN,tr|A0A0C4DGB1|A0A0C4DGB1_HUMAN,tr|A0A7P0T967|A0A7P0T967_HUMAN,tr|A0A7P0T9J1|A0A7P0T9J1_HUMAN,tr|A0A7P0Z4I0|A0A7P0Z4I0_HUMAN,tr|A0A7P0T9Y7|A0A7P0T9Y7_HUMAN,tr|D6RCL3|D6RCL3_HUMAN" 10 1246.7376 0.95 32848 18621 2 1246.744042 624.3761 Probable dimethyladenosine transferase OS=Homo sapiens OX=9606 GN=DIMT1 PE=1 SV=1 5.84 3590.5 - 654552 - - - 5.1366 - 2.363 0.304 - 568.1 1 2 0 0.0064 11 0 0 0 6.29E+06 6.63E+06 - - - 3.6107 0.9958 230117_WJC_METTL3_WT_vs_EV_F04.18623.18623.2 0.00113 14-Oct R.QAFYFALR[166.11].D "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1024.537 1.24 32850 18623 2 1024.542931 513.2758 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.75 3590.8 - 454047 - - - 5.8173 - 1.83 0.404 - 350.1 1 2 0 0.006 8 0 0 0 8.18E+06 6.62E+06 - - - 3.8457 0.9793 230117_WJC_METTL3_WT_vs_EV_F04.18625.18625.2 0.084 12-Jul K.LIFYDLR[166.11].G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 948.5308 1.16 32852 18625 2 948.536324 475.2727 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3591.1 - 427346 - - - 5.7995 - 1.425 0.227 - 181.7 1 2 0 0.0055 7 0 0 0 4.85E+07 4.18E+07 - - - 1.8381 1 230117_WJC_METTL3_WT_vs_EV_F04.18627.18627.2 1.66E-05 13/22 R.GIYTGLSAGLLR.Q "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 1219.6925 0.46 32854 18627 2 1219.697255 610.8535 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 8.75 3591.3 - 248217 - - - 3.9215 - 2.207 0.58 - 380.2 1 2 0 0.0048 12 0 0 0 1.15E+07 2.49E+07 - - - 5.4063 1 230117_WJC_METTL3_WT_vs_EV_F04.18628.18628.2 9.18E-05 20-Oct R.VYPQAVYFPIR.T "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1351.7289 2.53 32855 18628 2 1351.736486 676.8717 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.56 3591.4 - 215058 - - - 5.6431 - 2.256 0.467 - 452.2 1 2 0 0.0076 11 0 0 0 2.06E+06 8.13E+05 - - - 4.6888 0.9878 230117_WJC_METTL3_WT_vs_EV_F04.18638.18638.2 0.0433 16-Sep R.FLGTEVLLR.L "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN" 2 1046.6124 0.87 32864 18638 2 1046.618257 524.3135 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 6 3592.8 - 1.01E+06 - - - 5.5665 - 1.528 0.262 - 207.8 1 2 0 0.0058 9 0 0 0 1.12E+07 1.30E+07 - - - 2.2008 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.18640.18640.2 0.222 12-Jul K.LIFYDLR.G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 938.5226 1.15 32866 18640 2 938.524937 470.2686 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3592.9 - 1.33E+06 - - - 2.5402 - 1.523 0.295 - 192.1 1 2 0 0.0024 7 0 0 0 4.81E+07 4.18E+07 - - - 2.5521 0.9958 230117_WJC_METTL3_WT_vs_EV_F04.18642.18642.2 0.0537 16-Aug R.GDLLFLTNR[166.11].V "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 1057.5796 1.28 32868 18642 2 1057.580841 529.7971 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.84 3593.1 - 854771 - - - 1.2065 - 1.398 0.149 - 143.5 1 2 0 0.0013 9 0 0 0 1.09E+07 8.53E+06 - - - 1.1104 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18643.18643.2 0.000429 14-Sep R.QAFYFALR.D "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1014.5287 1.2 32869 18643 2 1014.531331 508.2716 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.75 3593.2 - 839616 - - - 2.5923 - 1.579 0.413 - 302 1 2 0 0.0026 8 0 0 0 7.91E+06 6.62E+06 - - - 3.4683 0.9918 230117_WJC_METTL3_WT_vs_EV_F04.18644.18644.2 0.000213 20-Jul R.VLPSITTEILK.S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1212.7329 1.45 32870 18644 2 1212.735009 607.3737 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 3593.3 - 822510 - - - 1.7061 - 1.589 0.064 - 134.6 2 2 0 0.0021 11 0 0 0 3.17E+08 2.18E+08 - - - 0.6314 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.18645.18645.2 0.203 16-Aug R.ALLLSTYIK.F "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|A0A0G2JS82|A0A0G2JS82_HUMAN,tr|A0A0G2JQM1|A0A0G2JQM1_HUMAN" 4 1020.6219 1.2 32871 18645 2 1020.622351 511.3182 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 8.63 3593.4 - 790085 - - - 0.4096 - 1.846 0.227 - 168.1 2 2 0 0.0004 9 0 0 0 9.23E+06 7.70E+06 - - - 2.3565 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.18647.18647.2 0.108 16-Sep R.ALLLSTYIK[136.11].F "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|A0A0G2JS82|A0A0G2JS82_HUMAN,tr|A0A0G2JQM1|A0A0G2JQM1_HUMAN" 4 1028.6361 1.27 32873 18647 2 1028.638502 515.3253 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 8.63 3593.6 - 586736 - - - 2.303 - 1.926 0.256 - 240.5 1 2 0 0.0024 9 0 0 0 9.23E+06 7.29E+06 - - - 2.8273 1 230117_WJC_METTL3_WT_vs_EV_F04.18648.18648.2 0.00434 22-Dec R.IGFDVVTLSGTR[166.11].G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1273.6906 0.89 32874 18648 2 1273.693588 637.8526 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.84 3593.7 - 559544 - - - 2.3679 - 2.336 0.462 - 396.8 1 2 0 0.003 12 0 0 0 5.38E+06 6.07E+06 - - - 4.6848 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.18652.18652.2 0.0251 16-Aug R.VLAINILGR.F sp|O43747|AP1G1_HUMAN 1 967.6179 0.33 32878 18652 2 967.619449 484.8162 AP-1 complex subunit gamma-1 OS=Homo sapiens OX=9606 GN=AP1G1 PE=1 SV=5 9.72 3594.1 - 200489 - - - 1.6515 - 1.67 0.278 - 162.9 1 2 0 0.0016 9 0 0 0 5.61E+06 1.68E+07 - - - 2.5774 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.18656.18656.2 0.054 14-Jul R.ILFFNTPK.K "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 978.5539 1.29 32880 18656 2 978.55688 490.2842 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 8.75 3594.6 - 1.02E+07 - - - 3.0923 - 1.453 0.358 - 142.2 1 2 0 0.003 8 0 0 0 6.79E+07 5.25E+07 - - - 2.8111 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.18657.18657.2 0.00751 20-Aug R.VLPSITTEILK[136.11].S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1220.7471 1.45 32881 18657 2 1220.750343 611.3808 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 3594.7 - 3.61E+06 - - - 2.6238 - 1.44 0.268 - 167.7 1 2 0 0.0032 11 0 0 0 3.17E+08 2.18E+08 - - - 2.0059 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18658.18658.2 5.42E-05 18-Sep K.ELLTSFGPLK[136.11].A "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1111.6369 1.6 32882 18658 2 1111.64033 556.8257 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6.1 3594.7 - 7.85E+06 - - - 3.1206 - 1.864 0.496 - 263.8 1 2 0 0.0035 10 0 0 0 6.37E+07 3.97E+07 - - - 4.4416 0.9789 230117_WJC_METTL3_WT_vs_EV_F04.18659.18659.2 1.48 12-Apr R.VLVWDLR[166.11].N "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 909.5312 2.04 32883 18659 2 909.533474 455.7729 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.81 3594.8 - 7.43E+06 - - - 2.5464 - 1.119 0.108 - 85.5 1 2 0 0.0023 7 0 0 0 5.50E+07 2.69E+07 - - - 0.1942 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.18661.18661.2 0.0163 16-Oct R.GDLLFLTNR.V "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 1047.5713 1.28 32885 18661 2 1047.57332 524.7929 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.84 3594.9 - 2.98E+06 - - - 1.933 - 1.614 0.245 - 292.8 1 2 0 0.002 9 0 0 0 1.09E+07 8.53E+06 - - - 2.2349 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.18670.18670.2 0.00218 14-Jul R.ELSPLFLR.F sp|O75691|UTP20_HUMAN 1 973.5597 0.93 32894 18670 2 973.56165 487.7871 Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3 6.1 3595.8 - 1.43E+06 - - - 2.0369 - 1.628 0.34 - 210.1 1 2 0 0.002 8 0 0 0 6.96E+06 7.48E+06 - - - 3.0214 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.18675.18675.2 0.000451 26-Dec K.YILVTGGVISGIGK.G "sp|P17812|PYRG1_HUMAN,sp|Q9NRF8|PYRG2_HUMAN,tr|A0A3B3ITH9|A0A3B3ITH9_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 7 1375.8075 2.68 32899 18675 2 1375.813658 688.911 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 8.59 3596.4 - 345441 - - - 4.4745 - 2.191 0.317 - 228.2 1 2 0 0.0062 14 0 0 0 3.94E+06 1.47E+06 - - - 3.3487 1 230117_WJC_METTL3_WT_vs_EV_F04.18677.18677.2 1.17E-06 26-Dec K.IVIPNEESVVIYYK[136.11].L sp|P42285|MTREX_HUMAN 1 1672.9167 0.72 32900 18677 2 1672.918373 837.4656 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.53 3596.8 - 78351.7 - - - 0.9851 - 2.373 0.602 - 361.5 1 2 0 0.0016 14 0 0 0 1.50E+06 2.09E+06 - - - 5.6554 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.18679.18679.2 0.138 14-Jun R.ILFFNTPK[136.11].K "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 986.5681 1.28 32902 18679 2 986.569859 494.2913 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 8.75 3596.9 - 1.83E+06 - - - 1.8296 - 1.406 0.301 - 68.6 1 2 0 0.0018 8 0 0 0 6.79E+07 5.30E+07 - - - 2.2913 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18681.18681.2 0.0052 12-Jun R.EFIEMWR[166.11].L "sp|Q7L0Y3|TM10C_HUMAN,tr|C9JVB6|C9JVB6_HUMAN" 2 1019.4774 0.79 32904 18681 2 1019.479322 510.746 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 4.53 3597.2 - 589482 - - - 1.8774 - 1.468 0.384 - 139.3 1 2 0 0.0019 7 0 0 0 6.01E+06 7.65E+06 - - - 3.093 0.976 230117_WJC_METTL3_WT_vs_EV_F04.18683.18683.2 2.72 12-May R.EFIEMWR.L "sp|Q7L0Y3|TM10C_HUMAN,tr|C9JVB6|C9JVB6_HUMAN" 2 1009.4691 0.79 32906 18683 2 1009.471912 505.7418 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 4.53 3597.4 - 413035 - - - 2.748 - 1.173 0.086 - 71.1 1 2 0 0.0028 7 0 0 0 6.01E+06 7.65E+06 - - - 0.1809 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18687.18687.2 9.63E-06 14-Sep K.C[160.03]QLLFALK.V "sp|Q9BRJ7|TIRR_HUMAN,tr|K7EIN2|K7EIN2_HUMAN" 2 991.5525 0.91 32910 18687 2 991.555059 496.7835 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3597.8 - 264950 - - - 2.607 - 1.87 0.478 - 289.5 1 2 0 0.0026 8 0 0 0 1.19E+07 1.31E+07 - - - 4.4585 1 230117_WJC_METTL3_WT_vs_EV_F04.18689.18689.2 7.08E-06 20-Oct K.FLEMC[160.03]NDLLAR.V "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1380.653 7.64 32912 18689 2 1380.657861 691.3338 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.37 3598 - 138942 - - - 3.5266 - 2.106 0.574 - 336.6 1 2 0 0.0049 11 0 0 0 2.62E+07 3.43E+06 - - - 5.2939 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.18692.18692.2 0.0211 16-Oct R.FEALNLSFK.N "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 12 1067.5651 1.69 32913 18692 2 1067.569239 534.7898 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 6 3598.4 - 6.98E+06 - - - 3.833 - 1.896 0.353 - 273.2 1 2 0 0.0041 9 0 0 0 8.58E+07 5.08E+07 - - - 3.4978 0.997 230117_WJC_METTL3_WT_vs_EV_F04.18693.18693.2 0.0521 14-Jul R.FLIQNVLR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1011.6105 1.49 32914 18693 2 1011.613917 506.8125 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.75 3598.5 - 2.09E+06 - - - 3.4064 - 1.627 0.223 - 162.7 1 2 0 0.0034 8 0 0 0 1.24E+08 8.34E+07 - - - 2.155 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.18694.18694.2 0.0495 18-Sep K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.15 32915 18694 2 1086.647377 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3598.6 - 1.15E+06 - - - 3.3553 - 1.911 0.322 - 176.8 1 2 0 0.0036 10 0 0 0 7.92E+07 6.86E+07 - - - 3.2259 0.9869 230117_WJC_METTL3_WT_vs_EV_F04.18695.18695.2 1.24 12-Jun R.NLPFLIK[136.11].K sp|Q86TB9|PATL1_HUMAN 1 851.536 1.28 32916 18695 2 851.537604 426.7753 Protein PAT1 homolog 1 OS=Homo sapiens OX=9606 GN=PATL1 PE=1 SV=2 8.75 3598.7 - 1.04E+06 - - - 1.8543 - 1.168 0.108 - 131.9 1 2 0 0.0016 7 0 0 0 1.46E+07 1.14E+07 - - - 0.3302 0.9756 230117_WJC_METTL3_WT_vs_EV_F04.18696.18696.2 3.17 18-Jul K.AIAINTFLPK[136.11].N sp|Q92615|LAR4B_HUMAN 1 1094.6579 1.15 32917 18696 2 1094.662078 548.3362 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3598.8 - 956042 - - - 3.7884 - 1.538 0.102 - 101 7 2 0 0.0041 10 0 0 0 7.92E+07 6.86E+07 - - - 0.6172 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.18697.18697.2 0.0106 12-Aug K.LYSLFLK.Y "sp|Q9P2R7|SUCB1_HUMAN,tr|Q5T9Q5|Q5T9Q5_HUMAN,tr|A0A0U1RRI1|A0A0U1RRI1_HUMAN,tr|A0A2R8YDQ9|A0A2R8YDQ9_HUMAN,tr|A0A2R8Y6Y7|A0A2R8Y6Y7_HUMAN,tr|Q5T9Q8|Q5T9Q8_HUMAN" 6 882.5215 2.75 32918 18697 2 882.523689 442.268 "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLA2 PE=1 SV=3" 8.59 3598.9 - 935291 - - - 2.4906 - 1.303 0.333 - 192.6 1 2 0 0.0022 7 0 0 0 1.34E+07 4.86E+06 - - - 2.3385 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18698.18698.2 0.0122 18-Aug R.LWTPPEDYRL.- "sp|Q9BYD1|RM13_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 2 1288.6452 1.46 32919 18698 2 1288.645796 645.3299 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.37 3599.1 - 651828 - - - 0.4718 - 1.808 0.333 - 331.2 1 2 0 0.0006 10 0 0 0 1.97E+07 1.35E+07 - - - 3.1534 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.18699.18699.2 0.0932 16-Sep K.ALLSALELK.K sp|P49454|CENPF_HUMAN 1 956.5906 1.13 32920 18699 2 956.592321 479.3026 Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3 6.05 3599.2 - 555380 - - - 1.7646 - 1.743 0.193 - 179.1 1 2 0 0.0017 9 0 0 0 4.26E+06 3.79E+06 - - - 2.0734 0.9956 230117_WJC_METTL3_WT_vs_EV_F04.18700.18700.2 0.0425 20-Jul R.C[160.03]FAGDTLLAIR[166.11].A sp|Q16254|E2F4_HUMAN 1 1245.6415 1.29 32921 18700 2 1245.642908 623.828 Transcription factor E2F4 OS=Homo sapiens OX=9606 GN=E2F4 PE=1 SV=2 5.83 3599.3 - 334102 - - - 1.1199 - 1.278 0.186 - 93.9 1 2 0 0.0014 11 0 0 0 2.67E+06 2.07E+06 - - - 1.0779 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.18702.18702.2 0.022 24-Sep K.ILTPLVSLDTPGK.A "sp|Q9HC38|GLOD4_HUMAN,tr|I3L1I0|I3L1I0_HUMAN,tr|F6TLX2|F6TLX2_HUMAN" 3 1352.7915 1.26 32923 18702 2 1352.790478 677.403 Glyoxalase domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GLOD4 PE=1 SV=1 5.84 3599.6 - 143363 - - - -0.7688 - 1.415 0.359 - 166.3 1 2 0 -0.001 13 0 0 0 1.75E+06 1.38E+06 - - - 2.5832 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.18703.18703.2 0.00278 13/24 R.LIEETISIAMATK[136.11].E "sp|O95249|GOSR1_HUMAN,tr|E9PCW1|E9PCW1_HUMAN,tr|G5E9T8|G5E9T8_HUMAN" 3 1426.7833 0.57 32924 18703 2 1426.790171 714.3989 Golgi SNAP receptor complex member 1 OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 4.53 3599.7 - 123976 - - - 4.8382 - 2.174 0.432 - 379.9 1 2 0 0.0069 13 0 0 0 1.99E+06 3.49E+06 - - - 4.2227 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18709.18709.2 0.00872 20-Oct K.YLLDSC[160.03]APLLR.Y sp|Q92616|GCN1_HUMAN 1 1319.6908 1.06 32928 18709 2 1319.692824 660.8527 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.83 3600.5 - 1.06E+06 - - - 1.5655 - 2.009 0.27 - 303.6 1 2 0 0.0021 11 0 0 0 6.94E+06 6.56E+06 - - - 2.9218 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.18710.18710.2 0.013 14-Sep R.FLIQNVLR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1001.6022 1.49 32929 18710 2 1001.605767 501.8084 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.75 3600.6 - 5.78E+06 - - - 3.5603 - 1.779 0.32 - 336.4 1 2 0 0.0036 8 0 0 0 1.24E+08 8.34E+07 - - - 3.1407 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18712.18712.2 0.000109 20-Nov K.YLLDSC[160.03]APLLR[166.11].Y sp|Q92616|GCN1_HUMAN 1 1329.699 1.06 32931 18712 2 1329.702055 665.8568 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.83 3600.8 - 897086 - - - 2.2765 - 1.815 0.5 - 366.2 1 2 0 0.003 11 0 0 0 6.94E+06 6.56E+06 - - - 4.3456 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.18713.18713.2 0.0472 14-Jul K.FEFLGINR.Q sp|Q8N3X1|FNBP4_HUMAN 1 994.5236 1.16 32932 18713 2 994.527192 498.2691 Formin-binding protein 4 OS=Homo sapiens OX=9606 GN=FNBP4 PE=1 SV=3 6 3600.9 - 659552 - - - 3.5957 - 1.572 0.229 - 122.8 1 2 0 0.0036 8 0 0 0 7.31E+06 6.30E+06 - - - 2.0955 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.18714.18714.2 0.0297 18-Sep K.LYGEFADPFK.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1185.5706 2.01 32933 18714 2 1185.574082 593.7926 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3601.1 - 498898 - - - 2.9151 - 1.614 0.44 - 190.8 1 2 0 0.0035 10 0 0 0 1.52E+07 7.55E+06 - - - 3.626 1 230117_WJC_METTL3_WT_vs_EV_F04.18715.18715.2 1.99E-08 15/26 R.ALMGSPQLVAAVVR.T "sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9J826|C9J826_HUMAN" 5 1410.8017 999 32934 18715 2 1410.806349 706.4081 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 9.79 3601.2 - 449892 - - - 3.2917 - 2.853 0.572 - 713 1 2 0 0.0046 14 0 0 0 1.66E+07 0.00E+00 - - - 5.8952 0.9965 230117_WJC_METTL3_WT_vs_EV_F04.18721.18721.2 0.168 12-May R.VLVWDLR.N "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 899.5229 1.4 32939 18721 2 899.525949 450.7687 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.81 3601.9 - 931328 - - - 3.4029 - 1.339 0.275 - 132.6 1 2 0 0.0031 7 0 0 0 5.82E+07 4.15E+07 - - - 1.9962 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18723.18723.2 0.000105 16-Sep K.LFTTMELMR.W sp|O00232|PSD12_HUMAN 1 1140.5671 1.82 32941 18723 2 1140.568949 571.2908 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 6 3602.1 - 471555 - - - 1.5887 - 1.848 0.434 - 213 1 2 0 0.0018 9 0 0 0 2.06E+07 1.13E+07 - - - 4.0226 0.999 230117_WJC_METTL3_WT_vs_EV_F04.18726.18726.2 0.0643 18-Jun R.LWTPPEDYR[166.11]L.- "sp|Q9BYD1|RM13_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 2 1298.6535 1.46 32944 18726 2 1298.656163 650.334 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.37 3602.4 - 368870 - - - 2.0829 - 1.583 0.301 - 165.6 1 2 0 0.0027 10 0 0 0 1.97E+07 1.35E+07 - - - 2.5454 0.8546 230117_WJC_METTL3_WT_vs_EV_F04.18732.18732.2 1.18 18-May K.LYGEFADPFK[136.11].L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1193.5848 2.01 32948 18732 2 1193.589379 597.7997 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3603 - 1.10E+06 - - - 3.8146 - 0.848 0.137 - 46.7 3 2 0 0.0046 10 0 0 0 1.52E+07 7.55E+06 - - - -0.6219 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.18733.18733.2 0.0127 18-Sep R.FEELC[160.03]SDLFR.S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1314.5914 24.19 32949 18733 2 1314.594315 658.303 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.14 3603.1 - 1.62E+06 - - - 2.1885 - 1.507 0.337 - 228.2 1 2 0 0.0029 10 0 0 0 7.11E+06 2.94E+05 - - - 2.674 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.18738.18738.2 0.00181 22-Jul K.LIDFGSAAYLER.G sp|Q96RG2|PASK_HUMAN 1 1353.6929 33.38 32954 18738 2 1353.697873 677.8537 PAS domain-containing serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=PASK PE=1 SV=3 4.37 3603.5 - 297610 - - - 3.6988 - 1.597 0.432 - 103.1 1 2 0 0.005 12 0 0 0 1.54E+06 4.63E+04 - - - 3.4619 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.18741.18741.2 0.00809 16-Sep R.FEALNLSFK[136.11].N "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 12 1075.5793 2.8 32956 18741 2 1075.579153 538.7969 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 6 3603.9 - 945104 - - - -0.1804 - 1.709 0.382 - 202.2 1 2 0 -0.0002 9 0 0 0 8.25E+07 2.94E+07 - - - 3.4128 1 230117_WJC_METTL3_WT_vs_EV_F04.18743.18743.2 7.93E-09 22-Dec K.FGEAIGMGFPVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1259.6464 0.98 32957 18743 2 1259.648263 630.8305 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3604.1 - 6.53E+06 - - - 1.4949 - 2.429 0.558 - 477.8 1 2 0 0.0019 12 0 0 0 2.04E+08 2.09E+08 - - - 5.4969 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.18745.18745.2 0.00308 18-Nov R.YDLGGLVMVK.D sp|Q15274|NADC_HUMAN 1 1093.5842 0.42 32959 18745 2 1093.588019 547.7994 Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Homo sapiens OX=9606 GN=QPRT PE=1 SV=3 5.83 3604.3 - 3.08E+06 - - - 3.5224 - 1.972 0.425 - 283 1 2 0 0.0039 10 0 0 0 2.94E+07 6.95E+07 - - - 4.0743 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18746.18746.2 0.000884 18-Nov R.IPDEIIDMVK.E "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1171.6159 2.43 32960 18746 2 1171.616247 586.8152 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 4.03 3604.4 - 2.02E+06 - - - 0.3286 - 1.778 0.412 - 360.9 1 2 0 0.0004 10 0 0 0 4.02E+07 1.66E+07 - - - 3.6903 0.9954 230117_WJC_METTL3_WT_vs_EV_F04.18747.18747.2 0.0071 16-Aug K.LFTTMELMR[166.11].W sp|O00232|PSD12_HUMAN 1 1150.5754 1.83 32961 18747 2 1150.581818 576.295 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 6 3604.6 - 1.26E+06 - - - 5.572 - 1.804 0.358 - 163.5 1 2 0 0.0064 9 0 0 0 2.04E+07 1.11E+07 - - - 3.3901 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.18759.18759.2 0.568 16-Nov K.ELIEELIAK[136.11].S "sp|P78316|NOP14_HUMAN,tr|E9PFK5|E9PFK5_HUMAN" 2 1064.6209 0.7 32971 18759 2 1064.622315 533.3177 Nucleolar protein 14 OS=Homo sapiens OX=9606 GN=NOP14 PE=1 SV=3 4.25 3606.2 - 1.09E+06 - - - 1.3507 - 2.003 0.217 - 363.2 1 2 0 0.0014 9 0 0 0 2.35E+07 3.36E+07 - - - 2.653 0.9753 230117_WJC_METTL3_WT_vs_EV_F04.18764.18764.2 0.669 14-Jul K.TIWSTMLR.L "sp|Q16850|CP51A_HUMAN,tr|H7C0D0|H7C0D0_HUMAN" 2 1006.527 1.64 32976 18764 2 1006.528387 504.2708 Lanosterol 14-alpha demethylase OS=Homo sapiens OX=9606 GN=CYP51A1 PE=1 SV=4 9.41 3606.7 - 495027 - - - 1.3909 - 0.969 0.124 - 105.9 1 2 0 0.0014 8 0 0 0 4.87E+06 2.98E+06 - - - -0.1386 0.9429 230117_WJC_METTL3_WT_vs_EV_F04.18774.18774.2 0.0106 14-Jul K.NSLESYAF.N "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 929.4131 - 32983 18774 2 929.414363 465.7138 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4 3607.8 - 889843 - - - 1.3987 - 1.218 0.413 - 139.6 1 1 0 0.0013 8 0 0 0 - - - - - 2.6858 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18776.18776.2 0.00174 20-Sep K.FLC[160.03]YLSQAGFR.V sp|Q7Z2T5|TRM1L_HUMAN 1 1360.6598 1.38 32985 18776 2 1360.662627 681.3372 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 8.22 3608.1 - 101928 - - - 2.0835 - 1.943 0.446 - 305.9 1 2 0 0.0028 11 0 0 0 6.57E+06 4.78E+06 - - - 4.1312 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18786.18786.2 1.44E-05 20-Dec K.IGDFGLVTSLK.N "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 3 1148.6441 999 32993 18786 2 1148.645346 575.3293 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 5.84 3609.3 - 789783 - - - 1.063 - 2.393 0.294 - 285.1 1 2 0 0.0012 11 0 0 0 2.83E+07 0.00E+00 - - - 3.5725 1 230117_WJC_METTL3_WT_vs_EV_F04.18787.18787.2 0.000196 22-Dec K.IIATVLMTEDIK[136.11].L "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 1353.7669 0.12 32994 18787 2 1353.767365 677.8907 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 3609.4 - 545801 - - - 0.3516 - 2.567 0.428 - 358.5 1 2 0 0.0005 12 0 0 0 7.80E+05 6.51E+06 - - - 4.6826 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18793.18793.2 0.00281 18-Oct R.ILVATNLFGR.G "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 6 1102.6499 1.31 32998 18793 2 1102.650274 552.3322 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 9.75 3610.1 - 6.41E+06 - - - 0.3582 - 2.171 0.455 - 324.5 1 2 0 0.0004 10 0 0 0 2.04E+08 1.56E+08 - - - 4.5653 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18794.18794.2 0.0529 16-Sep R.YLTVAAVFR.G "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 5 1038.5862 2.85 32999 18794 2 1038.587179 520.3004 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3610.2 - 6.41E+06 - - - 0.9272 - 1.894 0.403 - 264.2 1 2 0 0.001 9 0 0 0 5.61E+08 1.97E+08 - - - 3.865 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.18795.18795.2 0.556 14-Sep K.TVALWDLR.N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 972.5393 1.97 33000 18795 2 972.539918 487.2769 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3610.3 - 4.13E+06 - - - 0.6704 - 1.499 0.264 - 296.5 1 2 0 0.0007 8 0 0 0 3.97E+08 2.01E+08 - - - 2.2116 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18796.18796.2 0.00504 14-Sep K.TVALWDLR[166.11].N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 982.5475 1.97 33001 18796 2 982.547831 492.281 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3610.3 - 2.97E+06 - - - 0.3002 - 1.749 0.375 - 250.7 1 2 0 0.0003 8 0 0 0 3.97E+08 2.01E+08 - - - 3.4967 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.18798.18798.3 0.000744 Dec-40 R.ILVTLLHTLER.M sp|Q9BWD1|THIC_HUMAN 1 1306.7973 0.94 33003 18798 3 1306.796755 436.6064 "Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2" 6.75 3610.5 - 771846 - - - -0.3956 - 2.362 0.368 - 269.8 1 2 0 -0.0005 11 0 0 0 6.42E+06 6.80E+06 - - - 5.0844 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.18801.18801.2 0.000485 20-Nov K.FLC[160.03]YLSQAGFR[166.11].V sp|Q7Z2T5|TRM1L_HUMAN 1 1370.6681 1.4 33006 18801 2 1370.66504 686.3413 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 8.22 3610.9 - 432337 - - - -2.2048 - 1.815 0.406 - 359.5 1 2 0 -0.003 11 0 0 0 6.69E+06 4.78E+06 - - - 3.6513 0.923 230117_WJC_METTL3_WT_vs_EV_F04.18806.18806.2 0.00038 18-Aug R.FLLQDTVELR[166.11].E "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1242.6848 1.79 33009 18806 2 1243.691963 622.3497 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3611.6 - 4.34E+06 - - - 810.5072 - 1.684 0.423 - 205.3 1 2 0 1.0072 10 0 0 0 8.90E+07 4.96E+07 - - - 3.3038 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.18807.18807.3 0.0269 14/40 R.ILVTLLHTLER[166.11].M sp|Q9BWD1|THIC_HUMAN 1 1316.8055 0.93 33010 18807 3 1316.804695 439.9425 "Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2" 6.75 3611.7 - 1.27E+06 - - - -0.6432 - 2.514 0.441 - 281.4 1 2 0 -0.0008 11 0 0 0 6.17E+06 6.64E+06 - - - 6.0754 1 230117_WJC_METTL3_WT_vs_EV_F04.18812.18812.2 5.25E-07 13/20 K.VANVSLLALYK.G sp|P62266|RS23_HUMAN 1 1189.7071 0.98 33015 18812 2 1189.707091 595.8608 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3612.3 - 1.77E+06 - - - 0.0261 - 2.745 0.459 - 867.2 1 2 0 0 11 0 0 0 7.58E+08 7.77E+08 - - - 5.1629 0.9951 230117_WJC_METTL3_WT_vs_EV_F04.18814.18814.2 0.121 16-Sep R.ALVAVLLSR.T sp|Q92616|GCN1_HUMAN 1 940.607 1.13 33017 18814 2 940.60574 471.3108 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.79 3612.6 - 1.26E+06 - - - -1.2885 - 1.87 0.151 - 227 1 2 0 -0.0012 9 0 0 0 1.18E+07 1.05E+07 - - - 1.9668 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18818.18818.2 0.0206 16-Oct R.LDALLAELR[166.11].A sp|Q96L58|B3GT6_HUMAN 1 1022.6 1.42 33021 18818 2 1022.602468 512.3073 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 4.37 3613.1 - 695267 - - - 2.4467 - 2.395 0.236 - 310.7 1 2 0 0.0025 9 0 0 0 1.50E+07 1.05E+07 - - - 3.3101 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18820.18820.2 0.000155 20-Jul K.LYLNETFSELR.L "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C3Z5|H7C3Z5_HUMAN" 3 1383.7034 3.48 33023 18820 2 1383.707671 692.859 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 4.53 3613.3 - 647625 - - - 3.0642 - 1.92 0.433 - 123.1 1 2 0 0.0042 11 0 0 0 5.33E+06 1.53E+06 - - - 4.0025 1 230117_WJC_METTL3_WT_vs_EV_F04.18824.18824.2 0.00585 20-Dec K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 0.98 33026 18824 2 1197.72115 599.8679 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3613.7 - 5.79E+06 - - - -0.0918 - 2.524 0.415 - 664.4 1 2 0 -0.0001 11 0 0 0 7.58E+08 7.77E+08 - - - 4.6108 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.18827.18827.2 0.0426 12-Sep K.WMGIAFR.L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 879.4425 1.41 33029 18827 2 879.442245 440.7285 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.75 3614.1 - 1.51E+06 - - - -0.3229 - 1.46 0.261 - 266.3 1 2 0 -0.0003 7 0 0 0 1.80E+07 1.27E+07 - - - 2.1678 0.8962 230117_WJC_METTL3_WT_vs_EV_F04.18830.18830.2 0.0877 12-Aug L.SGFLVWR.R "sp|Q9NP84|TNR12_HUMAN,sp|Q96T88|UHRF1_HUMAN,tr|I3L1J9|I3L1J9_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 6 863.4654 1.57 33032 18830 2 863.465461 432.74 Tumor necrosis factor receptor superfamily member 12A OS=Homo sapiens OX=9606 GN=TNFRSF12A PE=1 SV=1 9.47 3614.5 - 855722 - - - 0.1019 - 1.476 0.28 - 233.7 1 1 0 0.0001 7 0 0 0 1.01E+07 6.46E+06 - - - 2.3427 1 230117_WJC_METTL3_WT_vs_EV_F04.18832.18832.2 4.96E-06 22-Dec K.SLAMEMVLTGDR.L sp|P30084|ECHM_HUMAN 1 1321.637 1 33034 18832 2 1321.639137 661.8258 "Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4" 4.37 3614.7 - 405824 - - - 1.6109 - 2.482 0.483 - 285.3 1 2 0 0.0021 12 0 0 0 3.78E+06 3.79E+06 - - - 4.9997 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.18836.18836.2 6.60E-05 24-Sep K.AEPLLGAPGELLK.Q sp|P17482|HXB9_HUMAN 1 1306.7497 2.3 33038 18836 2 1306.748275 654.3821 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 3615.2 - 294728 - - - -1.0545 - 2.001 0.469 - 222.3 1 2 0 -0.0014 13 0 0 0 1.57E+07 6.86E+06 - - - 4.2849 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18840.18840.2 0.000444 18-Sep R.FLLQDTVELR.E "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1232.6765 1.79 33040 18840 2 1232.677164 617.3455 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3615.8 - 1.50E+07 - - - 0.5484 - 2.056 0.378 - 316.2 1 2 0 0.0007 10 0 0 0 8.90E+07 4.96E+07 - - - 3.8446 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.18842.18842.2 0.0659 16-Oct R.LDALLAELR.A sp|Q96L58|B3GT6_HUMAN 1 1012.5917 0.99 33042 18842 2 1012.591751 507.3031 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 4.37 3616 - 2.60E+06 - - - 0.0543 - 2.462 0.181 - 406.4 1 2 0 0.0001 9 0 0 0 1.01E+07 1.02E+07 - - - 2.9844 0.9951 230117_WJC_METTL3_WT_vs_EV_F04.18843.18843.2 0.0198 12-Sep K.WMGIAFR[166.11].L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 889.4508 1.42 33043 18843 2 889.450314 445.7327 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.75 3616.1 - 2.04E+06 - - - -0.5453 - 1.228 0.253 - 321.3 1 2 0 -0.0005 7 0 0 0 1.78E+07 1.26E+07 - - - 1.5603 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.18846.18846.2 0.144 14-Aug R.ILLTLGIR.L "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 897.6011 1.13 33046 18846 2 897.60049 449.8078 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 9.75 3616.5 - 903901 - - - -0.7219 - 1.743 0.316 - 193.4 1 2 0 -0.0006 8 0 0 0 5.22E+06 4.64E+06 - - - 3.0505 0.9555 230117_WJC_METTL3_WT_vs_EV_F04.18848.18848.2 4.68 22-Aug K.AIGVGLGFELQR.L "sp|Q9NRN7|ADPPT_HUMAN,tr|E9PNF3|E9PNF3_HUMAN,tr|E9PLW6|E9PLW6_HUMAN" 3 1258.7034 24.61 33048 18848 2 1258.701442 630.359 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2 6.05 3616.7 - 599236 - - - -1.5325 - 1.365 0.102 - 97 4 2 0 -0.0019 12 0 0 0 5.70E+06 2.32E+05 - - - 0.3435 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18856.18856.3 0.00589 Sep-40 K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 1.02 33056 18856 3 1197.723779 400.2477 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3617.8 - 373604 - - - 2.1032 - 1.835 0.322 - 78.3 1 2 0 0.0025 11 0 0 0 1.99E+06 1.95E+06 - - - 3.8538 1 230117_WJC_METTL3_WT_vs_EV_F04.18859.18859.2 0.000343 18-Oct R.FEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1252.6088 11.23 33057 18859 2 1252.609258 627.3117 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3618.2 - 3.68E+06 - - - 0.364 - 2.164 0.566 - 378.7 1 2 0 0.0005 10 0 0 0 6.97E+08 6.21E+07 - - - 5.3761 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18865.18865.2 0.00427 13/18 K.IEVIEIMTDR[166.11].G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1227.6408 0.88 33063 18865 2 1227.642904 614.8277 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3618.7 - 333763 - - - 1.678 - 2.499 0.357 - 717.5 1 2 0 0.0021 10 0 0 0 1.08E+08 1.23E+08 - - - 4.2337 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18870.18870.2 0.157 16-Oct R.VEFILEQMR.L sp|O00232|PSD12_HUMAN 1 1163.6009 1.27 33068 18870 2 1163.600658 582.8077 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.53 3619.4 - 132367 - - - -0.1908 - 2.258 0.402 - 484.5 1 2 0 -0.0002 9 0 0 0 8.40E+06 6.64E+06 - - - 4.3664 0.999 230117_WJC_METTL3_WT_vs_EV_F04.18877.18877.2 0.00754 20-Oct K.TPPPVLIFAEK.K sp|Q9UJV9|DDX41_HUMAN 1 1210.6962 1.63 33074 18877 2 1210.695396 606.3554 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3620.1 - 667790 - - - -0.6319 - 1.806 0.362 - 274.3 1 2 0 -0.0008 11 0 0 0 7.22E+07 4.42E+07 - - - 3.3136 1 230117_WJC_METTL3_WT_vs_EV_F04.18882.18882.2 6.22E-05 13/20 R.LLDMDGIIVEK.Q sp|Q14152|EIF3A_HUMAN 1 1244.6686 1.64 33077 18882 2 1244.668612 623.3416 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.03 3620.7 - 515280 - - - -0.0104 - 2.679 0.391 - 363.8 1 2 0 0 11 0 0 0 4.18E+07 2.56E+07 - - - 4.5948 0.9942 230117_WJC_METTL3_WT_vs_EV_F04.18885.18885.2 1.41 14-Aug K.FIIPQIVK[136.11].Y "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 5 964.6201 0.78 33080 18885 2 964.621209 483.3173 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 8.75 3621 - 816895 - - - 1.1611 - 1.258 0.153 - 223.9 1 2 0 0.0011 8 0 0 0 2.32E+07 2.99E+07 - - - 0.8629 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18886.18886.2 0.042 14-Oct R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 12.66 33081 18886 2 1000.560093 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3621.2 - 256873 - - - 0.7596 - 2.174 0.264 - 300.5 1 2 0 0.0008 8 0 0 0 4.55E+06 3.60E+05 - - - 3.3328 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18890.18890.2 7.00E-05 14-Aug R.DFVNYLVR.L sp|Q08211|DHX9_HUMAN 1 1024.5342 0.86 33084 18890 2 1024.535913 513.2744 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.84 3621.6 - 6.29E+07 - - - 1.6905 - 1.621 0.364 - 264.3 1 2 0 0.0017 8 0 0 0 2.24E+08 2.60E+08 - - - 3.1858 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18894.18894.2 9.37E-05 13/20 R.IGFVGFPSVGK.S sp|Q9Y295|DRG1_HUMAN 1 1106.6124 1.8 33088 18894 2 1106.612587 554.3135 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 8.75 3621.8 - 7.92E+06 - - - 0.141 - 2.061 0.46 - 437.9 1 2 0 0.0002 11 0 0 0 4.48E+07 2.49E+07 - - - 4.3949 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.18895.18895.2 0.0547 20-Oct R.IGFVGFPSVGK[136.11].S sp|Q9Y295|DRG1_HUMAN 1 1114.6266 1.84 33089 18895 2 1114.625821 558.3206 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 8.75 3621.9 - 5.37E+06 - - - -0.7267 - 1.761 0.352 - 242.5 1 2 0 -0.0008 11 0 0 0 4.48E+07 2.44E+07 - - - 3.1715 1 230117_WJC_METTL3_WT_vs_EV_F04.18896.18896.2 0.000112 20-Dec R.LAVDLSEVVIK.W "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1184.7016 0.24 33090 18896 2 1184.703785 593.3581 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.37 3621.9 - 5.08E+06 - - - 1.8106 - 2.444 0.447 - 410.4 1 2 0 0.0021 11 0 0 0 1.15E+07 4.85E+07 - - - 4.7594 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.18897.18897.2 1.06 14-Jul R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 1.18 33091 18897 2 898.523863 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 3622 - 2.99E+06 - - - 0.2749 - 1.464 0.212 - 95.8 1 2 0 0.0002 8 0 0 0 8.72E+06 7.38E+06 - - - 1.7564 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.18898.18898.2 0.0464 14-Jun R.DLTDYLMK[136.11].L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 1005.4932 1.11 33092 18898 2 1005.493345 503.7539 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3622.1 - 2.64E+06 - - - 0.1104 - 1.166 0.314 - 104.1 1 2 0 0.0001 8 0 0 0 3.95E+07 3.54E+07 - - - 1.8234 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.18901.18901.2 0.0246 24-Dec K.AEPLLGAPGELLK[136.11].Q sp|P17482|HXB9_HUMAN 1 1314.7639 2.41 33095 18901 2 1314.761699 658.3892 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 3622.4 - 2.01E+06 - - - -1.6383 - 1.696 0.319 - 294.4 1 2 0 -0.0022 13 0 0 0 1.57E+07 6.55E+06 - - - 2.7523 0.8762 230117_WJC_METTL3_WT_vs_EV_F04.18904.18904.2 0.291 22-Jul R.VAGLQMTLTELR.A sp|P41229|KDM5C_HUMAN 1 1330.7279 12.38 33098 18904 2 1330.734834 666.3712 Lysine-specific demethylase 5C OS=Homo sapiens OX=9606 GN=KDM5C PE=1 SV=2 5.97 3622.8 - 1.28E+06 - - - 5.2317 - 1.419 0.039 - 96 2 2 0 0.007 12 0 0 0 5.84E+06 4.72E+05 - - - 0.1132 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.18905.18905.2 1.22E-05 20-Oct R.YLLEQDFPGMR.L "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN" 2 1367.6544 3.53 33099 18905 2 1367.659747 684.8345 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.37 3623 - 1.10E+06 - - - 3.9301 - 2.055 0.386 - 370.7 1 2 0 0.0054 11 0 0 0 2.87E+06 8.12E+05 - - - 3.8388 0.8678 230117_WJC_METTL3_WT_vs_EV_F04.18906.18906.2 2.33 12-Aug L.VGDVIQR[166.11].F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 795.4478 2.7 33100 18906 2 795.448046 398.7312 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.81 3623.1 - 754134 - - - 0.2816 - 1.849 0.135 - 263.2 1 1 0 0.0002 7 0 0 0 6.49E+06 2.41E+06 - - - 1.9856 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.18910.18910.2 0.0333 16-Aug R.SPTWFGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1059.5502 0.97 33103 18910 2 1059.550753 530.7824 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3623.6 - 3.36E+06 - - - 0.555 - 1.738 0.314 - 348.4 1 2 0 0.0006 9 0 0 0 3.99E+08 4.11E+08 - - - 2.9591 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18913.18913.2 0.00688 14-Aug R.DLTDYLMK.L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 997.479 1.11 33106 18913 2 997.480495 499.7468 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3623.9 - 597744 - - - 1.4647 - 1.522 0.367 - 188.5 1 2 0 0.0015 8 0 0 0 3.95E+07 3.54E+07 - - - 3.018 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.18914.18914.2 0.0359 12-May K.DYVDLFR.H sp|P78527|PRKDC_HUMAN 1 926.4498 0.37 33107 18914 2 926.450828 464.2322 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.21 3624 - 370544 - - - 1.129 - 1.129 0.257 - 101.5 1 2 0 0.001 7 0 0 0 9.90E+06 2.66E+07 - - - 1.3233 0.9773 230117_WJC_METTL3_WT_vs_EV_F04.18915.18915.2 0.191 16-Aug K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 0.03 33108 18915 2 1014.540742 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3624.2 - 352985 - - - 6.0786 - 1.696 0.184 - 147.3 1 2 0 0.0062 9 0 0 0 7.32E+06 2.24E+08 - - - 1.9264 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.18916.18916.2 0.00682 20-Nov R.ILLLGLDNAGK.T "sp|P36405|ARL3_HUMAN,sp|Q13795|ARFRP_HUMAN" 2 1125.6758 1.18 33109 18916 2 1125.678218 563.8452 ADP-ribosylation factor-like protein 3 OS=Homo sapiens OX=9606 GN=ARL3 PE=1 SV=2 5.84 3624.3 - 317880 - - - 2.1836 - 2.053 0.301 - 289.8 1 2 0 0.0025 11 0 0 0 1.35E+07 1.15E+07 - - - 3.2093 1 230117_WJC_METTL3_WT_vs_EV_F04.18917.18917.2 7.33E-05 13/22 K.IIENELEGFGIR[166.11].L sp|Q9Y295|DRG1_HUMAN 1 1398.7383 1.46 33110 18917 2 1398.730628 700.3764 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3624.4 - 196680 - - - -5.4492 - 2.371 0.516 - 490.8 1 2 0 -0.0076 12 0 0 0 7.78E+06 5.31E+06 - - - 5.1213 0.8955 230117_WJC_METTL3_WT_vs_EV_F04.18918.18918.2 0.0414 20-Nov R.ILLLGLDNAGK[136.11].T "sp|P36405|ARL3_HUMAN,sp|Q13795|ARFRP_HUMAN" 2 1133.69 1.18 33111 18918 2 1134.692112 567.8523 ADP-ribosylation factor-like protein 3 OS=Homo sapiens OX=9606 GN=ARL3 PE=1 SV=2 5.84 3624.6 - 177129 - - - 883.9736 - 2.007 0.372 - 287.3 1 2 0 1.0022 11 0 0 0 1.35E+07 1.15E+07 - - - 3.3585 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.18923.18923.2 0.00581 16-Sep K.GFGFVSFER[166.11].H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1054.5112 0.99 33114 18923 2 1054.51487 528.2629 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3625.2 - 1.36E+06 - - - 3.5268 - 1.775 0.418 - 320.9 1 2 0 0.0037 9 0 0 0 2.70E+08 2.73E+08 - - - 3.7872 1 230117_WJC_METTL3_WT_vs_EV_F04.18924.18924.2 0.00132 13/20 K.FAVALLDDSVR.V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1204.6452 1.48 33115 18924 2 1204.640893 603.3299 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 4.21 3625.3 - 397830 - - - -3.5654 - 2.55 0.498 - 588.9 1 2 0 -0.0043 11 0 0 0 1.15E+07 7.80E+06 - - - 5.2502 0.998 230117_WJC_METTL3_WT_vs_EV_F04.18925.18925.2 0.0423 16-Sep K.ILVTPWDYR.L sp|Q8TF46|DI3L1_HUMAN 1 1161.6182 0.35 33116 18925 2 1161.622164 581.8164 DIS3-like exonuclease 1 OS=Homo sapiens OX=9606 GN=DIS3L PE=1 SV=2 5.84 3625.4 - 332622 - - - 3.3737 - 1.775 0.248 - 222.7 1 2 0 0.0039 9 0 0 0 1.92E+06 5.48E+06 - - - 2.5315 0.9303 230117_WJC_METTL3_WT_vs_EV_F04.18931.18931.2 0.121 20-Aug R.LAQPYVGVFLK.R "sp|P36776|LONM_HUMAN,tr|K7EQF8|K7EQF8_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN" 4 1233.7121 0.29 33122 18931 2 1233.719364 617.8633 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 8.59 3626.2 - 136841 - - - 5.8514 - 1.378 0.127 - 114.3 1 2 0 0.0072 11 0 0 0 1.09E+06 3.75E+06 - - - 0.8441 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.18936.18936.2 9.16E-06 16-Oct K.GFGFVSFER.H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1044.5029 0.99 33125 18936 2 1044.507302 523.2587 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3626.9 - 6.05E+06 - - - 4.2326 - 1.821 0.467 - 408.9 1 2 0 0.0044 9 0 0 0 2.70E+08 2.73E+08 - - - 4.2229 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.18938.18938.2 0.00606 16-Jul K.GLDFALLQK[136.11].V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1011.5844 1.23 33127 18938 2 1011.587199 506.7995 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3627 - 3.56E+06 - - - 2.7353 - 1.694 0.361 - 133.9 1 2 0 0.0028 9 0 0 0 2.81E+07 2.28E+07 - - - 3.2314 1 230117_WJC_METTL3_WT_vs_EV_F04.18939.18939.2 2.96E-06 13/22 K.IIENELEGFGIR.L sp|Q9Y295|DRG1_HUMAN 1 1388.73 1.46 33128 18939 2 1388.732814 695.3723 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3627.1 - 1.70E+06 - - - 2.0407 - 2.644 0.406 - 564.9 1 2 0 0.0028 12 0 0 0 7.78E+06 5.31E+06 - - - 4.5971 1 230117_WJC_METTL3_WT_vs_EV_F04.18941.18941.2 9.84E-07 15/22 K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 2.17 33130 18941 2 1263.693946 632.853 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3627.3 - 1.38E+06 - - - 2.0021 - 2.32 0.521 - 544.6 1 2 0 0.0025 12 0 0 0 1.52E+07 7.01E+06 - - - 5.1026 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18942.18942.2 0.105 18-Oct K.LEPAFLSGLR.C "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1101.6182 1.32 33131 18942 2 1101.620456 551.8164 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3627.3 - 1.35E+06 - - - 2.007 - 2.214 0.337 - 311.5 1 2 0 0.0022 10 0 0 0 9.98E+06 7.55E+06 - - - 3.7479 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.18945.18945.2 0.0431 14-Jul R.ITNWLVLK.N "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN,tr|H3BRT3|H3BRT3_HUMAN" 3 985.5961 1.69 33134 18945 2 985.598592 493.8053 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 8.75 3627.6 - 857201 - - - 2.5761 - 1.465 0.257 - 87.2 1 2 0 0.0025 8 0 0 0 4.19E+06 2.47E+06 - - - 2.0901 1 230117_WJC_METTL3_WT_vs_EV_F04.18946.18946.2 0.00107 13/24 R.ILLAEVPTMAVEK[136.11].V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1420.8091 6.05 33135 18946 2 1420.812096 711.4118 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3627.7 - 638648 - - - 2.1164 - 2.483 0.462 - 467.4 1 2 0 0.003 13 0 0 0 2.76E+07 4.56E+06 - - - 4.7866 1 230117_WJC_METTL3_WT_vs_EV_F04.18947.18947.2 0.00098 20-Nov R.LMMDPLTGLNR[166.11].G "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1269.6449 0.89 33136 18947 2 1269.645464 635.8297 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.84 3627.8 - 621594 - - - 0.4568 - 2.221 0.493 - 393.5 1 2 0 0.0006 11 0 0 0 1.15E+07 1.30E+07 - - - 4.8408 1 230117_WJC_METTL3_WT_vs_EV_F04.18948.18948.2 0.000784 13/24 R.LDYLGVSYGLTPR[166.11].L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1462.7695 1 33137 18948 2 1462.774289 732.3921 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.83 3628 - 483871 - - - 3.2397 - 2.367 0.511 - 332.5 1 2 0 0.0047 13 0 0 0 3.73E+06 3.74E+06 - - - 5.0251 0.9743 230117_WJC_METTL3_WT_vs_EV_F04.18951.18951.2 0.427 16-Aug K.LYDPLLEYR.R "sp|Q13614|MTMR2_HUMAN,tr|A0A6Q8PHS7|A0A6Q8PHS7_HUMAN,tr|C9JEX3|C9JEX3_HUMAN,tr|A0A6Q8PGS5|A0A6Q8PGS5_HUMAN,tr|A0A6Q8PGV9|A0A6Q8PGV9_HUMAN" 5 1180.6128 0.61 33140 18951 2 1180.615589 591.3137 Myotubularin-related protein 2 OS=Homo sapiens OX=9606 GN=MTMR2 PE=1 SV=4 4.37 3628.3 - 287864 - - - 2.3412 - 1.277 0.033 - 141.6 1 2 0 0.0028 9 0 0 0 2.20E+06 3.63E+06 - - - -0.0087 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.18953.18953.3 0.0401 Sep-36 R.DFLLK[136.11]PELLR[166.11].A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1260.7561 1.25 33142 18953 3 1260.757892 421.2593 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3628.6 - 174095 - - - 1.438 - 1.924 0.319 - 100.3 1 2 0 0.0018 10 0 0 0 1.97E+07 1.59E+07 - - - 4.0072 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.18954.18954.2 8.03E-05 26-Dec K.LNLVDLAGSENIGR.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1469.7838 -1 33143 18954 2 1469.789166 735.8992 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 3628.7 - 170783 - - - 3.6461 - 2.302 0.434 - 420.7 1 2 0 0.0054 14 0 0 0 0.00E+00 0.00E+00 - - - 4.3372 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18956.18956.2 0.00385 18-Oct K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.2 33144 18956 2 1086.645779 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3629 - 6.52E+06 - - - 1.8847 - 1.801 0.357 - 285.5 1 2 0 0.002 10 0 0 0 2.25E+08 1.88E+08 - - - 3.3194 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.18957.18957.2 0.491 18-Aug K.AIAINTFLPK[136.11].N sp|Q92615|LAR4B_HUMAN 1 1094.6579 1.2 33145 18957 2 1094.660178 548.3362 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3629 - 4.90E+06 - - - 2.0527 - 1.666 0.16 - 140.9 2 2 0 0.0022 10 0 0 0 2.25E+08 1.88E+08 - - - 1.5123 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.18958.18958.2 0.00499 16-Sep K.GLDFALLQK.V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1003.5702 1.18 33146 18958 2 1003.573995 502.7924 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3629.1 - 9.89E+06 - - - 3.7496 - 1.816 0.389 - 213.1 1 2 0 0.0038 9 0 0 0 2.81E+07 2.38E+07 - - - 3.6391 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.18959.18959.2 0.0116 16-Nov K.LTQILSYLR[166.11].Q sp|Q13123|RED_HUMAN 1 1115.6578 1.59 33147 18959 2 1115.662795 558.8362 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3629.1 - 5.21E+06 - - - 4.4637 - 2.209 0.37 - 522 1 2 0 0.005 9 0 0 0 5.36E+07 3.38E+07 - - - 4.0651 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18960.18960.2 3.01E-06 22-Nov K.NIEDVIAQGIGK.L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1255.6772 2.21 33148 18960 2 1255.68095 628.8459 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3629.3 - 3.19E+06 - - - 2.9737 - 2.057 0.461 - 232 1 2 0 0.0037 12 0 0 0 1.55E+07 7.01E+06 - - - 4.3425 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.18962.18962.2 0.0374 18-Sep K.LLLGDLAPVR.G sp|Q9NUQ8|ABCF3_HUMAN 1 1065.6546 3.68 33150 18962 2 1065.657983 533.8346 ATP-binding cassette sub-family F member 3 OS=Homo sapiens OX=9606 GN=ABCF3 PE=1 SV=2 5.84 3629.4 - 2.28E+06 - - - 3.1464 - 1.901 0.301 - 196.9 1 2 0 0.0034 10 0 0 0 6.24E+06 1.70E+06 - - - 3.0562 0.999 230117_WJC_METTL3_WT_vs_EV_F04.18963.18963.2 0.000288 20-Dec K.TPPPVLIFAEK[136.11].K sp|Q9UJV9|DDX41_HUMAN 1 1218.7104 1.62 33151 18963 2 1218.714523 610.3625 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3629.5 - 2.27E+06 - - - 3.4151 - 1.628 0.425 - 442 1 2 0 0.0042 11 0 0 0 7.15E+07 4.41E+07 - - - 3.4971 1 230117_WJC_METTL3_WT_vs_EV_F04.18964.18964.2 7.41E-07 17/20 M.PPYTVVYFPVR.G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1336.718 1.2 33152 18964 2 1336.721469 669.3663 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3629.6 - 1.49E+06 - - - 2.6258 - 2.976 0.554 - 1497.4 1 2 0 0.0035 11 0 0 0 4.38E+07 3.65E+07 - - - 6.082 1 230117_WJC_METTL3_WT_vs_EV_F04.18965.18965.2 1.06E-06 13/20 K.MALDIEIATYR[166.11].K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1304.6674 1.5 33153 18965 2 1304.673149 653.341 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3629.7 - 1.41E+06 - - - 4.4119 - 2.747 0.543 - 776.5 1 2 0 0.0058 11 0 0 0 7.75E+07 5.15E+07 - - - 5.7835 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.18966.18966.3 0.000342 13/36 R.DFLLKPELLR.A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1242.7336 1.25 33154 18966 3 1242.737974 415.2518 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3629.9 - 1.16E+06 - - - 3.5124 - 2.394 0.365 - 229.6 1 2 0 0.0044 10 0 0 0 1.97E+07 1.59E+07 - - - 5.1576 1 230117_WJC_METTL3_WT_vs_EV_F04.18967.18967.2 2.16E-06 14/24 R.LDYLGVSYGLTPR.L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1452.7613 0.96 33155 18967 2 1452.76605 727.3879 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.83 3630 - 823753 - - - 3.2834 - 2.503 0.542 - 523 1 2 0 0.0048 13 0 0 0 3.73E+06 3.86E+06 - - - 5.3975 1 230117_WJC_METTL3_WT_vs_EV_F04.18968.18968.2 1.15E-05 14/18 K.C[160.03]LEEFELLGK.A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1236.606 1.07 33156 18968 2 1236.608439 619.3103 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3630.1 - 771123 - - - 1.9521 - 2.231 0.524 - 567.5 1 2 0 0.0024 10 0 0 0 5.03E+06 4.70E+06 - - - 5.1504 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.18969.18969.2 0.0637 18-Aug K.LLLGDLAPVR[166.11].G sp|Q9NUQ8|ABCF3_HUMAN 1 1075.6629 5.61 33157 18969 2 1075.667361 538.8387 ATP-binding cassette sub-family F member 3 OS=Homo sapiens OX=9606 GN=ABCF3 PE=1 SV=2 5.84 3630.2 - 714623 - - - 4.1472 - 1.598 0.351 - 158.1 1 2 0 0.0045 10 0 0 0 9.92E+06 1.77E+06 - - - 2.9405 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.18973.18973.3 0.0884 Oct-36 K.SAEFLLHMLK.N "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 1187.6373 0.98 33161 18973 3 1187.640689 396.8864 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 6.47 3630.7 - 379753 - - - 2.8822 - 1.966 0.304 - 106.8 1 2 0 0.0034 10 0 0 0 8.51E+05 8.68E+05 - - - 3.9026 1 230117_WJC_METTL3_WT_vs_EV_F04.18978.18978.2 2.21E-05 18-Nov K.C[160.03]LEEFELLGK[136.11].A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1244.6202 1.07 33165 18978 2 1244.625158 623.3174 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3631.3 - 1.54E+06 - - - 3.9635 - 2.212 0.498 - 329.2 1 2 0 0.0049 10 0 0 0 5.03E+06 4.70E+06 - - - 4.9337 1 230117_WJC_METTL3_WT_vs_EV_F04.18979.18979.2 1.16E-07 16/20 M.PPYTVVYFPVR[166.11].G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1346.7262 1.2 33166 18979 2 1346.729344 674.3704 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3631.3 - 7.41E+06 - - - 2.313 - 3.098 0.52 - 1195.4 1 2 0 0.0031 11 0 0 0 4.38E+07 3.65E+07 - - - 5.9397 0.9916 230117_WJC_METTL3_WT_vs_EV_F04.18982.18982.2 1.46 12-Aug R.WLLELSK[136.11].K sp|P35573|GDE_HUMAN 1 895.5259 0.79 33169 18982 2 895.524335 448.7702 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 6 3631.6 - 1.92E+06 - - - -1.6962 - 1.549 0.176 - 195.2 1 2 0 -0.0015 7 0 0 0 7.64E+06 9.62E+06 - - - 1.727 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.18983.18983.2 0.0125 16-Jun K.VQWGVFVPR[166.11].D sp|Q8IWA0|WDR75_HUMAN 1 1096.6057 1.49 33170 18983 2 1096.607625 549.3101 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 9.72 3631.7 - 1.99E+06 - - - 1.7372 - 1.446 0.295 - 149.2 1 2 0 0.0019 9 0 0 0 1.10E+07 7.42E+06 - - - 2.2862 1 230117_WJC_METTL3_WT_vs_EV_F04.18985.18985.2 4.80E-06 18-Oct K.GIFLGDDEWR[166.11].E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1216.5752 1.86 33172 18985 2 1216.577715 609.2949 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3631.9 - 1.34E+06 - - - 2.0615 - 2.153 0.521 - 341.5 1 2 0 0.0025 10 0 0 0 1.76E+07 9.50E+06 - - - 5.0289 0.9894 230117_WJC_METTL3_WT_vs_EV_F04.18986.18986.2 0.268 16-Sep R.LLIDEAILK[136.11].C "sp|P49591|SYSC_HUMAN,tr|Q5T5C7|Q5T5C7_HUMAN" 2 1034.6467 1.22 33173 18986 2 1034.650398 518.3306 "Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3" 4.37 3631.9 - 1.33E+06 - - - 3.5761 - 1.525 0.119 - 173.9 1 2 0 0.0037 9 0 0 0 5.13E+06 4.22E+06 - - - 1.1396 0.9851 230117_WJC_METTL3_WT_vs_EV_F04.18991.18991.2 0.00713 14-Aug K.LGTLFAFK[136.11].K sp|Q6F5E8|CARL2_HUMAN 1 903.5309 5.15 33178 18991 2 903.535941 452.7727 "Capping protein, Arp2\3 and myosin-I linker protein 2 OS=Homo sapiens OX=9606 GN=CARMIL2 PE=1 SV=2" 8.75 3632.5 - 809479 - - - 5.535 - 1.688 0.185 - 136.8 1 2 0 0.005 8 0 0 0 1.41E+07 2.74E+06 - - - 1.9848 0.9786 230117_WJC_METTL3_WT_vs_EV_F04.18994.18994.2 0.246 16-Jun R.SPTWFGIPR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1069.5584 0.97 33181 18994 2 1069.559372 535.7865 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3632.9 - 526891 - - - 0.8761 - 1.057 0.149 - 84.9 5 2 0 0.0009 9 0 0 0 3.98E+08 4.11E+08 - - - -0.0106 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.18996.18996.2 0.000353 24-Sep R.LLPPEDTQELIFK[136.11].D sp|O60287|NPA1P_HUMAN 1 1549.8483 -1 33183 18996 2 1549.851651 775.9314 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 4.14 3633.1 - 250686 - - - 2.155 - 1.913 0.355 - 149.6 1 2 0 0.0033 13 0 0 0 0.00E+00 0.00E+00 - - - 3.3268 1 230117_WJC_METTL3_WT_vs_EV_F04.18998.18998.2 2.05E-05 14/24 R.ILLAEVPTMAVEK.V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1412.7949 6.05 33184 18998 2 1412.797226 707.4047 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3633.3 - 735016 - - - 1.6542 - 2.546 0.515 - 640.4 1 2 0 0.0023 13 0 0 0 2.76E+07 4.56E+06 - - - 5.2425 1 230117_WJC_METTL3_WT_vs_EV_F04.19000.19000.2 1.53E-07 18-Sep K.GIFLGDDEWR.E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1206.5669 1.85 33186 19000 2 1206.568736 604.2907 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3633.5 - 2.51E+06 - - - 1.491 - 2.003 0.604 - 270.2 1 2 0 0.0018 10 0 0 0 1.76E+07 9.54E+06 - - - 5.4405 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19001.19001.2 0.092 14-Aug K.LLQQLFLK.A sp|Q9P287|BCCIP_HUMAN 1 1001.6274 1.38 33187 19001 2 1001.628832 501.821 BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1 8.75 3633.5 - 1.53E+06 - - - 1.4766 - 1.688 0.32 - 172.6 1 2 0 0.0015 8 0 0 0 1.22E+07 8.79E+06 - - - 2.983 0.999 230117_WJC_METTL3_WT_vs_EV_F04.19003.19003.2 0.0205 16-Jun K.VQWGVFVPR.D sp|Q8IWA0|WDR75_HUMAN 1 1086.5974 1.39 33189 19003 2 1086.599456 544.306 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 9.72 3633.6 - 1.42E+06 - - - 1.8461 - 1.425 0.323 - 128.2 1 2 0 0.002 9 0 0 0 9.87E+06 7.10E+06 - - - 2.4507 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19004.19004.2 2.73E-05 18-Nov K.TIC[160.03]AEFAILR.M "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1192.6274 0.71 33190 19004 2 1192.626994 597.321 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.66 3633.7 - 1.32E+06 - - - -0.3647 - 1.82 0.516 - 361 1 2 0 -0.0004 10 0 0 0 1.20E+07 1.69E+07 - - - 4.5236 0.9659 230117_WJC_METTL3_WT_vs_EV_F04.19006.19006.2 2.44 14-Apr K.LLQQLFLK[136.11].A sp|Q9P287|BCCIP_HUMAN 1 1009.6416 1.38 33192 19006 2 1009.642679 505.8281 BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1 8.75 3633.8 - 1.05E+06 - - - 1.1152 - 0.852 0.149 - 31.1 1 2 0 0.0011 8 0 0 0 1.22E+07 8.79E+06 - - - -0.3419 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19007.19007.2 0.000321 16-Oct K.ASSLISLLK.Q "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 930.575 2.63 33193 19007 2 930.575607 466.2948 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.8 3633.9 - 646404 - - - 0.6706 - 2.07 0.43 - 426.6 1 2 0 0.0006 9 0 0 0 2.94E+07 1.12E+07 - - - 4.3216 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19008.19008.2 0.0023 18-Sep R.LLLDTLQLSK.- "sp|O15357|SHIP2_HUMAN,tr|H7BXR2|H7BXR2_HUMAN" 2 1142.6911 1.44 33194 19008 2 1142.69255 572.3528 "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 OS=Homo sapiens OX=9606 GN=INPPL1 PE=1 SV=2" 5.84 3634 - 514259 - - - 1.2908 - 1.988 0.378 - 192.4 1 2 0 0.0015 10 0 0 0 5.17E+06 3.59E+06 - - - 3.7504 0.9941 230117_WJC_METTL3_WT_vs_EV_F04.19013.19013.2 0.747 12-Jun R.EYLYFLK.H sp|Q8N1N4|K2C78_HUMAN 1 974.5113 28.57 33197 19013 2 974.51297 488.2629 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 6.1 3634.6 - 694074 - - - 1.6932 - 1.143 0.19 - 125.6 1 2 0 0.0016 7 0 0 0 2.10E+07 7.36E+05 - - - 0.8673 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.19015.19015.2 0.0261 14-Aug R.LSFAVPFR.E sp|P78527|PRKDC_HUMAN 1 935.5229 1.15 33199 19015 2 935.52294 468.7687 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3634.8 - 438803 - - - 0.0556 - 1.934 0.261 - 189 1 2 0 0.0001 8 0 0 0 2.06E+07 1.79E+07 - - - 2.958 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19016.19016.2 0.00126 20-Aug R.FLMSLVNQVPK.L "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 1274.7057 1.07 33200 19016 2 1274.707565 638.3601 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 8.75 3634.9 - 322118 - - - 1.4788 - 1.507 0.411 - 159.9 1 2 0 0.0019 11 0 0 0 3.79E+07 3.55E+07 - - - 3.1855 1 230117_WJC_METTL3_WT_vs_EV_F04.19020.19020.2 0.00417 16-Oct K.FALNSLLQR.Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1060.6029 1.97 33202 19020 2 1060.605489 531.3087 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.75 3635.5 - 1.61E+06 - - - 2.4137 - 2.255 0.44 - 369.2 1 2 0 0.0026 9 0 0 0 3.57E+07 1.81E+07 - - - 4.6425 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19021.19021.2 6.84E-06 13/18 R.LMALLGQALK[136.11].W sp|Q2TAY7|SMU1_HUMAN 1 1064.6507 1 33203 19021 2 1064.653638 533.3326 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.75 3635.6 - 1.32E+06 - - - 2.7248 - 2.415 0.402 - 590.2 1 2 0 0.0029 10 0 0 0 3.07E+07 3.06E+07 - - - 4.4704 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.19022.19022.2 0.000275 14-Oct R.LSFAVPFR[166.11].E sp|P78527|PRKDC_HUMAN 1 945.5312 1.15 33204 19022 2 945.535183 473.7729 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3635.8 - 1.05E+06 - - - 4.2569 - 1.897 0.352 - 378.5 1 2 0 0.004 8 0 0 0 2.06E+07 1.79E+07 - - - 3.5706 0.9935 230117_WJC_METTL3_WT_vs_EV_F04.19023.19023.2 0.000296 16-Dec K.IIDGLLVMR[166.11].K "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1038.6135 3.25 33205 19023 2 1038.618667 520.314 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.84 3635.9 - 965409 - - - 4.9682 - 2.109 0.167 - 385.5 1 2 0 0.0052 9 0 0 0 9.57E+07 2.95E+07 - - - 2.4317 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.19024.19024.2 3.47E-06 16-Oct K.MC[160.03]LFAGFQR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1128.5209 0.9 33206 19024 2 1128.525788 565.2677 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3636 - 876569 - - - 4.3703 - 2.103 0.361 - 591.8 1 2 0 0.0049 9 0 0 0 6.90E+07 7.70E+07 - - - 3.8564 1 230117_WJC_METTL3_WT_vs_EV_F04.19025.19025.2 0.00017 16-Oct K.FALNSLLQR[166.11].Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1070.6112 2.14 33207 19025 2 1070.614909 536.3129 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.75 3636.2 - 798252 - - - 3.4653 - 2.037 0.483 - 415.4 1 2 0 0.0037 9 0 0 0 3.56E+07 1.66E+07 - - - 4.6656 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19027.19027.2 0.00148 18-Oct R.DFLLKPELLR.A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1242.7336 1.93 33209 19027 2 1242.736454 622.3741 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3636.4 - 498321 - - - 2.2893 - 1.964 0.362 - 421.3 1 2 0 0.0028 10 0 0 0 5.73E+06 2.96E+06 - - - 3.5979 0.9936 230117_WJC_METTL3_WT_vs_EV_F04.19029.19029.2 0.0465 22-Sep K.TPLPPELADVQA.- "sp|Q9Y5V0|ZN706_HUMAN,tr|H0YC70|H0YC70_HUMAN" 2 1249.6554 - 33211 19029 2 1249.660197 625.835 Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1 3.67 3636.7 - 239214 - - - 3.8243 - 1.633 0.185 - 241.6 1 2 0 0.0048 12 0 0 0 - - - - - 1.6963 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19031.19031.3 6.52E-05 Dec-36 K.FLPFSFEHIR.E "sp|Q93050|VPP1_HUMAN,tr|F5H1T6|F5H1T6_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 4 1291.6713 1.3 33213 19031 3 1291.676107 431.5644 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 6.75 3636.9 - 203063 - - - 3.6882 - 1.933 0.445 - 148.4 1 2 0 0.0048 10 0 0 0 2.01E+06 1.55E+06 - - - 5.4248 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19034.19034.2 1.41E-05 24-Aug R.LLPPEDTQELIFK.D sp|O60287|NPA1P_HUMAN 1 1541.8341 0.87 33216 19034 2 1541.839224 771.9243 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 4.14 3637.3 - 115832 - - - 3.3162 - 2.029 0.5 - 117.9 1 2 0 0.0051 13 0 0 0 2.72E+06 3.14E+06 - - - 4.5483 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.19035.19035.3 0.00146 Oct-40 R.FPFLGVHFTPR.M "sp|Q9H9P8|L2HDH_HUMAN,tr|C9JVN9|C9JVN9_HUMAN" 2 1316.703 1.9 33217 19035 3 1316.705982 439.9083 "L-2-hydroxyglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=L2HGDH PE=1 SV=3" 9.76 3637.5 - 89719.2 - - - 2.2822 - 2.15 0.227 - 63.7 1 2 0 0.003 11 0 0 0 1.63E+06 8.60E+05 - - - 3.2446 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19038.19038.3 0.00102 Aug-36 R.LFDQAFGLPR[166.11].L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1172.6218 1.22 33220 19038 3 1172.624494 391.8812 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3637.9 - 56342.7 - - - 2.3281 - 1.432 0.41 - 57.9 1 2 0 0.0027 10 0 0 0 1.78E+06 1.47E+06 - - - 4.159 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19043.19043.2 0.000414 16-Aug K.VFDAIMNFK[136.11].K sp|P13639|EF2_HUMAN 1 1091.5565 4.05 33223 19043 2 1091.557463 546.7855 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.81 3638.4 - 2.59E+06 - - - 0.8795 - 1.641 0.367 - 147.2 1 2 0 0.001 9 0 0 0 7.74E+07 1.91E+07 - - - 3.1843 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19047.19047.2 0.00164 18-Oct K.TIC[160.03]AEFAILR[166.11].M "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1202.6357 1.12 33227 19047 2 1202.636614 602.3251 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.66 3638.9 - 678887 - - - 0.7608 - 1.579 0.407 - 302.5 1 2 0 0.0009 10 0 0 0 1.07E+07 9.53E+06 - - - 3.3219 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19050.19050.3 0.00324 Oct-36 R.LFDQAFGLPR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1162.6135 1.17 33230 19050 3 1162.615799 388.5451 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3639.3 - 291661 - - - 1.9826 - 1.773 0.318 - 109.5 1 2 0 0.0023 10 0 0 0 1.78E+06 1.52E+06 - - - 3.7572 0.9918 230117_WJC_METTL3_WT_vs_EV_F04.19051.19051.2 0.127 20-Nov K.GPILMELQTYR.Y "sp|P08559|ODPA_HUMAN,sp|P29803|ODPAT_HUMAN" 2 1319.6908 2 33231 19051 2 1319.698874 660.8527 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 6 3639.4 - 151483 - - - 6.1499 - 1.754 0.346 - 121.8 1 2 0 0.0081 11 0 0 0 5.68E+06 2.84E+06 - - - 3.1141 0.9928 230117_WJC_METTL3_WT_vs_EV_F04.19053.19053.3 0.0483 Jul-36 K.FLPFSFEHIR[166.11].E "sp|Q93050|VPP1_HUMAN,tr|F5H1T6|F5H1T6_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 4 1301.6796 1.25 33233 19053 3 1301.675782 434.9005 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 6.75 3639.7 - 99362.6 - - - -2.9431 - 1.498 0.323 - 53.4 1 2 0 -0.0038 10 0 0 0 2.77E+06 2.21E+06 - - - 3.3203 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.19055.19055.2 1.36E-05 16-Sep K.MC[160.03]LFAGFQR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1138.5291 0.9 33234 19055 2 1138.533456 570.2718 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3639.9 - 9.87E+06 - - - 3.8032 - 1.851 0.365 - 484.5 1 2 0 0.0043 9 0 0 0 6.90E+07 7.70E+07 - - - 3.5169 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19057.19057.2 0.076 16-Aug R.LQLPVWEYK[136.11].D sp|O43143|DHX15_HUMAN 1 1182.6528 2.3 33236 19057 2 1182.655384 592.3337 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 3640.1 - 1.77E+06 - - - 2.146 - 1.586 0.368 - 233.7 1 2 0 0.0025 9 0 0 0 7.73E+07 3.36E+07 - - - 3.0926 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19063.19063.2 0.00346 22-Sep K.GALPLDTVTFYK.V sp|P30040|ERP29_HUMAN 1 1323.7075 1.23 33242 19063 2 1323.710073 662.861 Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4 5.83 3640.9 - 243064 - - - 1.9785 - 1.777 0.369 - 192.8 1 2 0 0.0026 12 0 0 0 4.44E+06 3.61E+06 - - - 3.2783 0.9701 230117_WJC_METTL3_WT_vs_EV_F04.19065.19065.2 0.00012 24-Sep R.GFVPDTPVGVAHF.L "sp|Q6DN90|IQEC1_HUMAN,tr|A0A0C4DGT3|A0A0C4DGT3_HUMAN,tr|A0A2R8Y7T6|A0A2R8Y7T6_HUMAN,tr|A0A3B3IRZ4|A0A3B3IRZ4_HUMAN,tr|A0A2R8Y695|A0A2R8Y695_HUMAN,tr|A0A3B3IU98|A0A3B3IU98_HUMAN" 6 1341.6717 - 33244 19065 2 1341.673215 671.8431 IQ motif and SEC7 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=IQSEC1 PE=1 SV=1 5.08 3641.2 - 209286 - - - 1.1016 - 1.743 0.429 - 59.4 1 1 0 0.0015 13 0 0 0 - - - - - 3.6351 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19068.19068.2 0.0264 14-Jul R.IPLNDLFR.C sp|P13473|LAMP2_HUMAN 1 986.5549 6.53 33246 19068 2 986.55718 494.2847 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3641.5 - 8.81E+06 - - - 2.2949 - 1.801 0.31 - 224.5 1 2 0 0.0023 8 0 0 0 9.00E+07 1.38E+07 - - - 3.1044 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.19070.19070.2 0.00202 16-Sep K.SGILPILVK.C sp|O00505|IMA4_HUMAN 1 938.6165 1.32 33247 19070 2 938.621099 470.3155 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3641.7 - 3.20E+06 - - - 4.9488 - 1.858 0.373 - 208.6 1 2 0 0.0046 9 0 0 0 3.04E+07 2.30E+07 - - - 3.5868 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.19071.19071.2 0.664 16-Jul K.SGILPILVK[136.11].C sp|O00505|IMA4_HUMAN 1 946.6307 1.32 33248 19071 2 946.63379 474.3226 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3641.8 - 2.53E+06 - - - 3.3128 - 1.217 0.28 - 109.3 1 2 0 0.0031 9 0 0 0 3.04E+07 2.30E+07 - - - 1.6763 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19072.19072.2 0.0125 16-Aug K.IIDGLLVMR.K "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1028.6052 3.2 33249 19072 2 1028.607856 515.3099 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.84 3641.8 - 6.51E+06 - - - 2.5462 - 1.878 0.331 - 141.8 1 2 0 0.0026 9 0 0 0 9.80E+07 3.06E+07 - - - 3.3082 0.967 230117_WJC_METTL3_WT_vs_EV_F04.19074.19074.2 0.0922 16-Oct S.GDLLSEVER.N "sp|O14513|NCKP5_HUMAN,tr|A0A0A0MSE4|A0A0A0MSE4_HUMAN,tr|A0A0A0MS79|A0A0A0MS79_HUMAN" 3 1016.5138 9.4 33251 19074 2 1016.515923 509.2642 Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=2 4.14 3642 - 2.36E+06 - - - 2.0501 - 2.063 0.341 - 471.6 1 1 0 0.0021 9 0 0 0 6.90E+07 7.34E+06 - - - 3.654 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19075.19075.2 0.00112 18-Sep K.SVPDEIILLR.S sp|Q9H9A6|LRC40_HUMAN 1 1153.6707 2.15 33252 19075 2 1153.674885 577.8426 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.37 3642 - 955816 - - - 3.6501 - 1.826 0.466 - 390.7 1 2 0 0.0042 10 0 0 0 2.10E+07 9.78E+06 - - - 4.1623 0.9929 230117_WJC_METTL3_WT_vs_EV_F04.19076.19076.2 0.0517 14-Jul R.IPLNDLFR[166.11].C sp|P13473|LAMP2_HUMAN 1 996.5632 7.91 33253 19076 2 996.567262 499.2889 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3642.1 - 919954 - - - 4.0901 - 1.441 0.219 - 142 1 2 0 0.0041 8 0 0 0 8.85E+07 1.12E+07 - - - 1.7591 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19077.19077.2 0.000842 24-Nov R.ALGLGLVSPAQLR.V "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|A8MRA7|A8MRA7_HUMAN" 3 1293.7769 3.17 33254 19077 2 1293.780207 647.8957 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 9.79 3642.1 - 694155 - - - 2.5785 - 2.417 0.232 - 460.9 1 2 0 0.0033 13 0 0 0 5.75E+06 1.81E+06 - - - 3.0185 0.998 230117_WJC_METTL3_WT_vs_EV_F04.19080.19080.2 0.551 14-Aug R.VLLLPLER.D sp|O95071|UBR5_HUMAN 1 951.6117 1.81 33257 19080 2 951.613754 476.8131 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3642.4 - 642365 - - - 2.1553 - 1.71 0.166 - 234.1 1 2 0 0.0021 8 0 0 0 1.79E+07 9.87E+06 - - - 1.8845 0.9618 230117_WJC_METTL3_WT_vs_EV_F04.19081.19081.2 3.08 16-May R.LTAILLQIK.C "sp|Q5TKA1|LIN9_HUMAN,tr|C9J5J4|C9J5J4_HUMAN,tr|H0Y322|H0Y322_HUMAN,tr|H7C4T7|H7C4T7_HUMAN" 4 1011.6692 2.27 33258 19081 2 1011.671599 506.8419 Protein lin-9 homolog OS=Homo sapiens OX=9606 GN=LIN9 PE=1 SV=1 8.75 3642.5 - 537942 - - - 2.3535 - 1.116 0.102 - 39.9 7 2 0 0.0024 9 0 0 0 2.09E+06 9.21E+05 - - - -0.2664 1 230117_WJC_METTL3_WT_vs_EV_F04.19083.19083.2 5.69E-06 24-Oct R.LLPGEEC[160.03]VLDGLR.V sp|O95248|MTMR5_HUMAN 1 1469.7548 1.61 33260 19083 2 1469.757291 735.8847 Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4 4.14 3642.7 - 331491 - - - 1.6846 - 2.119 0.526 - 299 1 2 0 0.0025 13 0 0 0 2.44E+06 1.52E+06 - - - 4.8526 0.9893 230117_WJC_METTL3_WT_vs_EV_F04.19084.19084.2 0.00129 24-Oct R.LLPGEEC[160.03]VLDGLR[166.11].V sp|O95248|MTMR5_HUMAN 1 1479.7631 1.61 33261 19084 2 1479.774552 740.8888 Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4 4.14 3642.9 - 264102 - - - 7.7492 - 1.991 0.471 - 231.8 1 2 0 0.0115 13 0 0 0 2.44E+06 1.52E+06 - - - 4.2836 0.9905 230117_WJC_METTL3_WT_vs_EV_F04.19089.19089.2 1.77 14-Jun R.VLLLPLER[166.11].D sp|O95071|UBR5_HUMAN 1 961.62 1.78 33264 19089 2 961.623873 481.8173 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3643.5 - 1.21E+06 - - - 4.0557 - 1.472 0.173 - 121 1 2 0 0.0039 8 0 0 0 1.79E+07 1.01E+07 - - - 1.4836 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.19090.19090.2 0.0263 14-Jul K.MIDLIIPR[166.11].G sp|P54886|P5CS_HUMAN 1 979.5764 1.68 33265 19090 2 979.580576 490.7955 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 5.59 3643.6 - 749225 - - - 4.2702 - 1.589 0.305 - 149.9 2 2 0 0.0042 8 0 0 0 7.00E+06 4.16E+06 - - - 2.5546 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.19092.19092.2 0.00152 12-Aug R.IQLLVFK[136.11].H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 867.5673 0.69 33267 19092 2 867.569725 434.7909 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3643.9 - 610295 - - - 2.7664 - 1.9 0.058 - 183.5 1 2 0 0.0024 7 0 0 0 1.76E+07 2.54E+07 - - - 1.5024 1 230117_WJC_METTL3_WT_vs_EV_F04.19097.19097.2 1.01E-06 14/32 R.AAVEEGIVLGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1683.8978 2.49 33272 19097 2 1683.901056 842.9562 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3644.5 - 251048 - - - 1.939 - 2.939 0.47 - 488.4 1 2 0 0.0033 17 0 0 0 1.17E+06 4.70E+05 - - - 5.1619 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.19107.19107.2 0.9 16-Sep R.LQLPVWEYK.D sp|O43143|DHX15_HUMAN 1 1174.6386 2.28 33281 19107 2 1174.643276 588.3266 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 3645.8 - 3.03E+06 - - - 3.9416 - 1.774 0.253 - 248 1 2 0 0.0046 9 0 0 0 7.69E+07 3.37E+07 - - - 2.5666 0.9767 230117_WJC_METTL3_WT_vs_EV_F04.19109.19109.2 0.00524 18-Dec K.SVVTSIFGVK.N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1035.5964 1.6 33283 19109 2 1035.606528 518.8055 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3646.1 - 1.45E+06 - - - 9.7345 - 2.137 0.317 - 382.3 1 2 0 0.0101 10 0 0 0 2.78E+07 1.73E+07 - - - 3.4989 0.9921 230117_WJC_METTL3_WT_vs_EV_F04.19110.19110.2 0.0158 14-Nov K.MIDLIIPR.G sp|P54886|P5CS_HUMAN 1 969.5681 1.66 33284 19110 2 969.574505 485.7913 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 5.59 3646.2 - 1.26E+06 - - - 6.5823 - 1.963 0.343 - 537.5 1 2 0 0.0064 8 0 0 0 7.00E+06 4.21E+06 - - - 3.6066 0.9744 230117_WJC_METTL3_WT_vs_EV_F04.19112.19112.2 0.836 12-Aug R.IQLLVFK.H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 859.5531 0.69 33286 19112 2 859.557929 430.7838 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3646.5 - 1.06E+06 - - - 5.589 - 1.733 0.101 - 208.5 1 2 0 0.0048 7 0 0 0 1.76E+07 2.54E+07 - - - 1.5277 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.19113.19113.2 0.0103 16-Oct K.LLIYWASTR.E sp|P06312|KV401_HUMAN 1 1121.6233 83.9 33287 19113 2 1121.627912 561.8189 Immunoglobulin kappa variable 4-1 OS=Homo sapiens OX=9606 GN=IGKV4-1 PE=1 SV=1 8.75 3646.6 - 805866 - - - 4.0852 - 1.944 0.299 - 364.5 1 2 0 0.0046 9 0 0 0 2.10E+07 2.50E+05 - - - 3.1711 0.9914 230117_WJC_METTL3_WT_vs_EV_F04.19114.19114.2 0.0179 12-Jul R.DYLQLLR.K sp|L0R6Q1|S35U4_HUMAN 1 919.5127 1.62 33288 19114 2 919.517891 460.7636 SLC35A4 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=SLC35A4 PE=3 SV=1 5.84 3646.8 - 748474 - - - 5.6269 - 1.494 0.312 - 250.2 1 2 0 0.0052 7 0 0 0 6.20E+06 3.83E+06 - - - 2.6158 1 230117_WJC_METTL3_WT_vs_EV_F04.19115.19115.2 0.000158 18-Nov K.SVVTSIFGVK[136.11].N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1043.6106 1.75 33289 19115 2 1043.616843 522.8126 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3646.9 - 728677 - - - 5.9371 - 2.244 0.467 - 346.7 1 2 0 0.0062 10 0 0 0 2.44E+07 1.39E+07 - - - 4.7444 1 230117_WJC_METTL3_WT_vs_EV_F04.19116.19116.2 7.35E-08 20-Dec R.FSTIEEFSYIR.R "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1390.6769 1.39 33290 19116 2 1390.685096 696.3457 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 4.53 3647 - 583140 - - - 5.9065 - 2.577 0.612 - 650.9 1 2 0 0.0082 11 0 0 0 2.46E+06 1.77E+06 - - - 6.1195 0.999 230117_WJC_METTL3_WT_vs_EV_F04.19117.19117.2 3.51E-05 20-Oct R.FSTIEEFSYIR[166.11].R "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1400.6852 1.39 33291 19117 2 1400.691046 701.3499 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 4.53 3647.1 - 437884 - - - 4.2079 - 1.974 0.5 - 305.6 1 2 0 0.0059 11 0 0 0 2.46E+06 1.77E+06 - - - 4.5719 0.9829 230117_WJC_METTL3_WT_vs_EV_F04.19119.19119.2 0.00743 20-Sep K.LIDFGSGALLK.D "sp|P11309|PIM1_HUMAN,sp|Q86V86|PIM3_HUMAN" 2 1132.6492 0.04 33293 19119 2 1132.657265 567.3319 Serine\threonine-protein kinase pim-1 OS=Homo sapiens OX=9606 GN=PIM1 PE=1 SV=4 5.84 3647.4 - 398399 - - - 7.1108 - 1.662 0.34 - 130.3 1 2 0 0.0081 11 0 0 0 2.03E+06 4.68E+07 - - - 2.924 1 230117_WJC_METTL3_WT_vs_EV_F04.19121.19121.2 0.00886 13/20 K.LLEVQILEVQR.A "sp|Q8IWJ2|GCC2_HUMAN,tr|H7BYJ9|H7BYJ9_HUMAN" 2 1338.7871 1.24 33295 19121 2 1338.795718 670.4008 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.53 3647.7 - 337835 - - - 6.4364 - 2.419 0.453 - 838.6 1 2 0 0.0086 11 0 0 0 1.59E+06 1.28E+06 - - - 4.7738 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.19122.19122.2 0.00118 14/22 K.LSTIALALGVER[166.11].T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1251.7426 2.14 33296 19122 2 1251.748362 626.8786 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3647.8 - 332840 - - - 4.5976 - 2.559 0.362 - 701.9 1 2 0 0.0058 12 0 0 0 2.97E+07 1.39E+07 - - - 4.1852 0.9922 230117_WJC_METTL3_WT_vs_EV_F04.19127.19127.2 0.00118 18-Sep R.LEPVIMELER[166.11].Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1237.6616 0.69 33300 19127 2 1237.668627 619.8381 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3648.4 - 709433 - - - 5.6938 - 1.663 0.315 - 149.7 1 2 0 0.007 10 0 0 0 5.29E+07 7.64E+07 - - - 2.7851 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.19128.19128.2 0.0246 14-Sep K.ILTPIIFK.E "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5L9|H7C5L9_HUMAN" 4 943.6106 0.51 33301 19128 2 943.614683 472.8126 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 8.75 3648.5 - 1.77E+06 - - - 4.2846 - 1.808 0.439 - 227.6 1 2 0 0.004 8 0 0 0 1.15E+07 2.24E+07 - - - 4.0683 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.19129.19129.2 0.00109 16-Sep K.EAEILEVLR[166.11].H sp|P36551|HEM6_HUMAN 1 1080.6054 1.17 33302 19129 2 1080.604045 541.31 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.25 3648.6 - 1.71E+06 - - - -1.2956 - 1.937 0.313 - 239.7 1 2 0 -0.0014 9 0 0 0 8.96E+06 7.66E+06 - - - 3.2651 0.9928 230117_WJC_METTL3_WT_vs_EV_F04.19131.19131.2 0.21 14-Aug K.GLLQLQWK[136.11].Q sp|O94826|TOM70_HUMAN 1 992.5899 1.13 33304 19131 2 992.593642 497.3022 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.75 3648.8 - 1.10E+06 - - - 3.8183 - 1.326 0.229 - 169.8 1 2 0 0.0038 8 0 0 0 7.13E+06 6.30E+06 - - - 1.5822 0.9298 230117_WJC_METTL3_WT_vs_EV_F04.19134.19134.2 0.00146 24-Aug R.SYEAVAAAAASVY.N sp|Q9BWF3|RBM4_HUMAN 1 1271.6034 - 33307 19134 2 1271.607311 636.809 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4 3649.1 - 549304 - - - 3.089 - 1.617 0.403 - 189.4 1 1 0 0.0039 13 0 0 0 - - - - - 3.2497 0.99 230117_WJC_METTL3_WT_vs_EV_F04.19135.19135.2 0.327 20-Jul K.ELFPIQMEGVK[136.11].L "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 1297.6832 0.83 33308 19135 2 1297.685754 649.8489 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.53 3649.3 - 453919 - - - 1.9989 - 1.401 0.08 - 130.8 1 2 0 0.0026 11 0 0 0 4.29E+06 5.17E+06 - - - 0.5432 0.9917 230117_WJC_METTL3_WT_vs_EV_F04.19136.19136.2 5.86E-05 20-Nov K.ELFPIQMEGVK.L "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 1289.669 0.84 33309 19136 2 1289.678505 645.8418 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.53 3649.4 - 445156 - - - 7.4011 - 1.946 0.5 - 388.3 1 2 0 0.0095 11 0 0 0 4.36E+06 5.17E+06 - - - 4.5321 0.9778 230117_WJC_METTL3_WT_vs_EV_F04.19139.19139.2 0.0238 20-Jun K.LFGALTPLEPR[166.11].L "sp|O14617|AP3D1_HUMAN,tr|A0A087WYN6|A0A087WYN6_HUMAN,tr|A0A2R8Y4J3|A0A2R8Y4J3_HUMAN" 3 1222.6949 1.92 33312 19139 2 1222.703009 612.3547 AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1 6 3649.8 - 284703 - - - 6.6084 - 1.55 0.279 - 66.3 1 2 0 0.0081 11 0 0 0 3.63E+06 1.89E+06 - - - 2.2847 0.9961 230117_WJC_METTL3_WT_vs_EV_F04.19140.19140.2 0.684 14-Sep K.LAIVLFTK[136.11].E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 911.5935 1.81 33313 19140 2 911.597564 456.804 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3649.9 - 275827 - - - 4.4142 - 1.922 0.213 - 181.7 1 2 0 0.004 8 0 0 0 3.21E+06 1.77E+06 - - - 2.5835 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.19146.19146.2 0.003 18-Nov R.IIVAIDGWPR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1138.6499 2.3 33317 19146 2 1138.652832 570.3322 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3650.7 - 7.39E+06 - - - 2.5934 - 2.355 0.121 - 411.9 1 2 0 0.003 10 0 0 0 6.11E+07 2.65E+07 - - - 2.3246 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19147.19147.2 0.00511 18-Oct R.IIVAIDGWPR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1148.6581 2.51 33318 19147 2 1148.66155 575.3364 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3650.7 - 3.44E+06 - - - 2.9608 - 2.168 0.349 - 330.4 1 2 0 0.0034 10 0 0 0 6.66E+07 2.65E+07 - - - 3.7776 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.19148.19148.2 0.00205 16-Nov K.VFSIGPVFR[166.11].A sp|P14868|SYDC_HUMAN 1 1030.5839 1.13 33319 19148 2 1030.589262 516.2992 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3650.8 - 2.47E+06 - - - 5.1815 - 2.069 0.455 - 468 1 2 0 0.0053 9 0 0 0 3.29E+07 2.92E+07 - - - 4.5034 1 230117_WJC_METTL3_WT_vs_EV_F04.19150.19150.2 6.43E-05 16-Nov R.QINWTVLYR.R "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1191.64 0.99 33321 19150 2 1191.647047 596.8273 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 8.75 3651 - 1.50E+06 - - - 5.8776 - 2.382 0.474 - 779.4 1 2 0 0.007 9 0 0 0 2.97E+07 3.00E+07 - - - 5.0508 0.9186 230117_WJC_METTL3_WT_vs_EV_F04.19151.19151.2 0.00875 24-Nov K.AALEAVGGTVVLE.- sp|P52815|RM12_HUMAN 1 1227.6711 - 33322 19151 2 1227.679282 614.8428 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 4.24 3651.1 - 998278 - - - 6.6907 - 1.931 0.073 - 220.7 2 2 0 0.0082 13 0 0 0 - - - - - 1.132 0.9938 230117_WJC_METTL3_WT_vs_EV_F04.19153.19153.2 0.303 14-Oct K.LAIVLFTK.E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 903.5793 1.81 33324 19153 2 903.583975 452.7969 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3651.4 - 602740 - - - 5.1296 - 1.998 0.2 - 262 1 2 0 0.0046 8 0 0 0 3.21E+06 1.77E+06 - - - 2.6042 0.8683 230117_WJC_METTL3_WT_vs_EV_F04.19154.19154.2 0.413 14-Jul R.SIFDYALR.S "sp|Q99570|PI3R4_HUMAN,tr|D6RBB7|D6RBB7_HUMAN,tr|D6RJ98|D6RJ98_HUMAN,tr|D6RAC3|D6RAC3_HUMAN" 4 983.5076 3.68 33325 19154 2 983.513486 492.7611 Phosphoinositide 3-kinase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PIK3R4 PE=1 SV=3 5.55 3651.5 - 599855 - - - 5.9522 - 1.07 0.156 - 102 1 2 0 0.0059 8 0 0 0 2.64E+06 7.20E+05 - - - 0.3954 0.997 230117_WJC_METTL3_WT_vs_EV_F04.19155.19155.2 0.0196 20-Aug K.LFGALTPLEPR.L "sp|O14617|AP3D1_HUMAN,tr|A0A087WYN6|A0A087WYN6_HUMAN,tr|A0A2R8Y4J3|A0A2R8Y4J3_HUMAN" 3 1212.6867 2.16 33326 19155 2 1212.685376 607.3506 AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1 6 3651.7 - 329527 - - - -1.058 - 1.429 0.312 - 147 1 2 0 -0.0013 11 0 0 0 4.09E+06 1.89E+06 - - - 2.3107 0.9832 230117_WJC_METTL3_WT_vs_EV_F04.19165.19165.2 0.0188 12-Jun R.DYLQLLR[166.11].K sp|L0R6Q1|S35U4_HUMAN 1 929.521 1.62 33335 19165 2 929.526929 465.7678 SLC35A4 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=SLC35A4 PE=3 SV=1 5.84 3652.9 - 90561.3 - - - 6.3925 - 1.392 0.318 - 100 1 2 0 0.0059 7 0 0 0 6.20E+06 3.83E+06 - - - 2.4359 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19167.19167.2 0.00125 16-Oct K.VFSIGPVFR.A sp|P14868|SYDC_HUMAN 1 1020.5757 1.13 33336 19167 2 1020.578168 511.2951 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3653.2 - 6.47E+06 - - - 2.4653 - 1.913 0.411 - 388.5 1 2 0 0.0025 9 0 0 0 3.29E+07 2.92E+07 - - - 3.9525 0.9763 230117_WJC_METTL3_WT_vs_EV_F04.19169.19169.2 0.0224 12-Jun K.QFLDYFK.T "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 959.4753 1.23 33338 19169 2 959.478958 480.7449 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.83 3653.4 - 1.04E+06 - - - 3.8448 - 1.227 0.132 - 134 1 2 0 0.0037 7 0 0 0 6.68E+06 5.44E+06 - - - 0.663 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.19170.19170.2 0.0129 18-Jul K.LLVLSALAEK.L sp|Q13395|TARB1_HUMAN 1 1055.659 1.6 33339 19170 2 1055.664042 528.8368 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6 3653.6 - 877937 - - - 4.7316 - 1.643 0.427 - 104.2 1 2 0 0.005 10 0 0 0 3.50E+06 2.18E+06 - - - 3.5792 0.9814 230117_WJC_METTL3_WT_vs_EV_F04.19171.19171.2 0.156 12-May K.QFLDYFK[136.11].T "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 967.4895 1.23 33340 19171 2 967.493811 484.752 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.83 3653.7 - 682353 - - - 4.4879 - 1.201 0.211 - 95.3 1 2 0 0.0043 7 0 0 0 6.68E+06 5.44E+06 - - - 1.1784 1 230117_WJC_METTL3_WT_vs_EV_F04.19172.19172.2 4.63E-05 18-Nov K.ELPEYYELIR.K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1323.6711 1.67 33341 19172 2 1323.675846 662.8428 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3653.8 - 677853 - - - 3.6097 - 2.106 0.505 - 564.4 1 2 0 0.0048 10 0 0 0 1.49E+07 8.94E+06 - - - 4.8484 0.9551 230117_WJC_METTL3_WT_vs_EV_F04.19174.19174.2 0.303 12-May R.YVLNFLR.T "sp|Q8NC69|KCTD6_HUMAN,tr|F5H7I0|F5H7I0_HUMAN" 2 923.5229 3.38 33343 19174 2 923.526915 462.7687 BTB\POZ domain-containing protein KCTD6 OS=Homo sapiens OX=9606 GN=KCTD6 PE=1 SV=2 8.75 3654.1 - 519842 - - - 4.3605 - 1.079 0.201 - 63.9 5 2 0 0.004 7 0 0 0 2.17E+06 6.42E+05 - - - 0.453 0.9907 230117_WJC_METTL3_WT_vs_EV_F04.19175.19175.2 0.0149 16-Jul R.TFLHTVC[160.03]FY.- sp|Q9NP77|SSU72_HUMAN 1 1186.5481 - 33344 19175 2 1186.553677 594.2813 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 OS=Homo sapiens OX=9606 GN=SSU72 PE=1 SV=1 6.4 3654.2 - 447961 - - - 4.6859 - 1.281 0.289 - 113.6 1 2 0 0.0056 9 0 0 0 - - - - - 1.8902 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.19177.19177.2 0.00694 16-Jul K.LYQEMFAWK.M "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1214.5794 2.01 33346 19177 2 1214.583906 608.297 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3654.5 - 410740 - - - 3.6968 - 1.404 0.318 - 116.3 1 2 0 0.0045 9 0 0 0 3.06E+06 1.52E+06 - - - 2.37 0.9967 230117_WJC_METTL3_WT_vs_EV_F04.19179.19179.2 0.00908 18-Sep K.ELPEYYELIR[166.11].K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1333.6793 1.67 33348 19179 2 1333.68518 667.8469 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3654.7 - 353782 - - - 4.3804 - 1.56 0.333 - 333.6 1 2 0 0.0058 10 0 0 0 1.49E+07 8.94E+06 - - - 2.74 1 230117_WJC_METTL3_WT_vs_EV_F04.19187.19187.2 0.00557 13/20 R.GVIFTEAFVAR.H sp|O94874|UFL1_HUMAN 1 1208.6554 1.93 33355 19187 2 1208.660041 605.335 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 6 3655.9 - 869121 - - - 3.8737 - 2.607 0.436 - 446.9 1 2 0 0.0047 11 0 0 0 7.81E+06 4.04E+06 - - - 4.852 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.19189.19189.2 0.0134 18-Jul R.LWIANYSLPR[166.11].A sp|O43172|PRP4_HUMAN 1 1241.6796 3.39 33357 19189 2 1241.683838 621.8471 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3656 - 2.40E+06 - - - 3.4026 - 1.983 0.262 - 158.9 1 2 0 0.0042 10 0 0 0 9.29E+07 2.74E+07 - - - 2.8858 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19191.19191.2 0.00373 16-Aug R.LSYPTFFPR.F "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1126.5811 1.67 33359 19191 2 1126.580465 564.2978 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 8.75 3656.2 - 1.01E+06 - - - -0.5912 - 1.61 0.426 - 182.7 1 2 0 -0.0007 9 0 0 0 2.30E+07 1.38E+07 - - - 3.565 0.999 230117_WJC_METTL3_WT_vs_EV_F04.19193.19193.2 0.0192 16-Aug K.IFAFDLDAK[136.11].R sp|Q96P11|NSUN5_HUMAN 1 1046.5528 0.83 33361 19193 2 1046.554118 524.2837 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 4.21 3656.4 - 526278 - - - 1.2622 - 1.476 0.306 - 98.7 1 2 0 0.0013 9 0 0 0 9.89E+06 1.20E+07 - - - 2.4271 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19194.19194.2 0.000359 16-Oct K.ISVNDFIIK[136.11].A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1055.6106 0.86 33362 19194 2 1055.614571 528.8126 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 3656.5 - 505416 - - - 3.7173 - 2.084 0.412 - 196.5 1 2 0 0.0039 9 0 0 0 1.17E+07 1.37E+07 - - - 4.2071 1 230117_WJC_METTL3_WT_vs_EV_F04.19195.19195.2 9.25E-06 15/22 R.VVYSAFLMATPR.L sp|Q15029|U5S1_HUMAN 1 1353.7115 1.47 33363 19195 2 1353.715922 677.863 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.72 3656.7 - 467805 - - - 3.2717 - 2.642 0.511 - 788.6 1 2 0 0.0044 12 0 0 0 8.99E+06 6.12E+06 - - - 5.3701 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.19197.19197.2 0.00209 12-Jul K.FGFIGFK[136.11].S sp|Q9Y4C8|RBM19_HUMAN 1 822.452 1 33365 19197 2 822.454377 412.2333 Probable RNA-binding protein 19 OS=Homo sapiens OX=9606 GN=RBM19 PE=1 SV=3 8.75 3656.9 - 386642 - - - 2.9376 - 1.415 0.363 - 117.2 1 2 0 0.0024 7 0 0 0 3.36E+06 3.37E+06 - - - 2.8213 1 230117_WJC_METTL3_WT_vs_EV_F04.19198.19198.2 1.16E-06 22-Dec R.LC[160.03]LTDEEVVFVR[166.11].L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1488.7522 10.25 33366 19198 2 1488.74673 745.3834 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3657.1 - 106429 - - - -3.6648 - 2.563 0.547 - 557.7 1 2 0 -0.0055 12 0 0 0 7.54E+06 7.36E+05 - - - 5.5558 0.997 230117_WJC_METTL3_WT_vs_EV_F04.19202.19202.2 0.000892 16-Sep K.ISVNDFIIK.A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1047.5964 0.86 33368 19202 2 1047.60141 524.8055 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 3657.5 - 1.73E+06 - - - 4.7375 - 1.71 0.352 - 155.5 1 2 0 0.005 9 0 0 0 1.17E+07 1.37E+07 - - - 3.1914 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.19203.19203.2 0.014 18-Jul R.FFLSSGLIDK[136.11].V sp|Q9BTV4|TMM43_HUMAN 1 1133.6212 1.05 33369 19203 2 1133.622423 567.8179 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 5.84 3657.6 - 1.85E+06 - - - 1.0691 - 1.431 0.298 - 109.9 1 2 0 0.0012 10 0 0 0 1.33E+07 1.26E+07 - - - 2.242 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19204.19204.2 6.67E-05 22-Nov K.VLGTEELYGYLK[136.11].K "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1391.7428 1.05 33370 19204 2 1391.747913 696.8787 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.53 3657.7 - 2.09E+06 - - - 3.686 - 2.248 0.425 - 279 1 2 0 0.0051 12 0 0 0 1.89E+07 1.80E+07 - - - 4.3098 1 230117_WJC_METTL3_WT_vs_EV_F04.19205.19205.2 5.59E-05 22-Dec K.VLGTEELYGYLK.K "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1383.7286 1.05 33371 19205 2 1383.734039 692.8716 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.53 3657.8 - 2.03E+06 - - - 3.943 - 2.493 0.548 - 374.8 1 2 0 0.0055 12 0 0 0 1.89E+07 1.80E+07 - - - 5.4904 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.19206.19206.2 0.000717 16-Sep K.IFAFDLDAK.R sp|Q96P11|NSUN5_HUMAN 1 1038.5386 0.84 33372 19206 2 1038.543696 520.2766 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 4.21 3657.9 - 1.23E+06 - - - 4.9098 - 1.773 0.497 - 214.2 1 2 0 0.0051 9 0 0 0 9.89E+06 1.17E+07 - - - 4.367 1 230117_WJC_METTL3_WT_vs_EV_F04.19207.19207.2 1.88E-07 15/24 V.ALVMLQEDELLSK.M sp|Q96A49|SYAP1_HUMAN 1 1487.7905 1.5 33373 19207 2 1487.796725 744.9025 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3657.9 - 1.21E+06 - - - 4.1625 - 2.96 0.524 - 805.5 1 1 0 0.0062 13 0 0 0 4.08E+07 2.72E+07 - - - 5.6945 1 230117_WJC_METTL3_WT_vs_EV_F04.19208.19208.2 5.86E-06 22-Dec R.LC[160.03]LTDEEVVFVR.L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1478.7439 10.25 33374 19208 2 1478.747492 740.3792 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3658.1 - 1.18E+06 - - - 2.4183 - 2.433 0.588 - 626.6 1 2 0 0.0036 12 0 0 0 7.54E+06 7.36E+05 - - - 5.7223 0.9438 230117_WJC_METTL3_WT_vs_EV_F04.19209.19209.2 1.91E-06 24-Dec V.ALVMLQEDELLSK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1495.8047 1.5 33375 19209 2 1495.810058 748.9096 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3658.2 - 942591 - - - 3.5606 - 2.647 0.364 - 445.7 1 1 0 0.0053 13 0 0 0 4.08E+07 2.72E+07 - - - 4.2262 0.999 230117_WJC_METTL3_WT_vs_EV_F04.19211.19211.2 0.000374 18-Sep R.FMEPYIFGSR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 1255.5935 1.11 33377 19211 2 1255.598333 628.804 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 6 3658.5 - 564795 - - - 3.8492 - 1.861 0.426 - 316.2 1 2 0 0.0048 10 0 0 0 3.49E+06 3.15E+06 - - - 3.9196 0.9793 230117_WJC_METTL3_WT_vs_EV_F04.19212.19212.2 0.2 14-May K.GLLDVLPK[136.11].N "sp|O95071|UBR5_HUMAN,tr|E7ET84|E7ET84_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 861.5415 2.5 33378 19212 2 861.543233 431.778 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.84 3658.6 - 518788 - - - 2.0069 - 1.059 0.142 - 45.9 3 2 0 0.0017 8 0 0 0 1.59E+07 6.38E+06 - - - 0.049 1 230117_WJC_METTL3_WT_vs_EV_F04.19213.19213.2 4.11E-07 16/24 R.IPSPLGYAAIPIK[136.11].F sp|Q9Y3A4|RRP7A_HUMAN 1 1346.8053 1.43 33379 19213 2 1346.810256 674.4099 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 8.59 3658.7 - 509093 - - - 3.662 - 2.358 0.576 - 451.4 1 2 0 0.0049 13 0 0 0 3.87E+07 2.70E+07 - - - 5.4954 0.9763 230117_WJC_METTL3_WT_vs_EV_F04.19214.19214.2 4.28 12-Jun R.LWAELLR[166.11].T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN" 3 909.5312 1.36 33380 19214 2 909.53343 455.7729 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 6 3658.8 - 406657 - - - 2.498 - 1.323 0.052 - 102.9 3 2 0 0.0023 7 0 0 0 5.47E+06 4.02E+06 - - - 0.0981 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19215.19215.2 0.0152 20-Oct R.ELAYQTFEVLR[166.11].K "sp|Q13206|DDX10_HUMAN,tr|A0A3B3ISR7|A0A3B3ISR7_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 3 1377.7168 1.16 33381 19215 2 1377.719368 689.8657 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 4.53 3659 - 233763 - - - 1.8741 - 1.761 0.301 - 361.1 1 2 0 0.0026 11 0 0 0 2.94E+06 2.52E+06 - - - 2.7942 0.971 230117_WJC_METTL3_WT_vs_EV_F04.19221.19221.2 0.084 18-May R.VTIMGIYSIK[136.11].K "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 3 1131.6453 1.62 33385 19221 2 1131.650568 566.8299 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 8.56 3659.7 - 5.46E+06 - - - 4.6393 - 1.081 0.224 - 59.6 1 2 0 0.0053 10 0 0 0 2.22E+07 1.37E+07 - - - 0.9112 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19222.19222.2 0.00274 22-Oct R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.12 33386 19222 2 1323.803264 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3659.7 - 8.02E+06 - - - 2.0328 - 1.878 0.411 - 260.9 1 2 0 0.0027 12 0 0 0 1.56E+09 1.39E+09 - - - 3.734 1 230117_WJC_METTL3_WT_vs_EV_F04.19223.19223.2 6.93E-05 22-Nov R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.12 33387 19223 2 1315.789721 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3659.8 - 6.95E+06 - - - 2.5445 - 2.236 0.55 - 367.7 1 2 0 0.0033 12 0 0 0 1.56E+09 1.39E+09 - - - 5.2195 1 230117_WJC_METTL3_WT_vs_EV_F04.19224.19224.2 0.00118 26-Nov K.VLELDPALAPVVSR.E "sp|O00170|AIP_HUMAN,tr|A0A804HKK3|A0A804HKK3_HUMAN,tr|A0A804HKL7|A0A804HKL7_HUMAN,tr|A0A804HJ46|A0A804HJ46_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN" 6 1477.8504 4.84 33388 19224 2 1477.853726 739.9325 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 4.37 3659.8 - 4.93E+06 - - - 2.2303 - 2.341 0.49 - 280.3 1 2 0 0.0033 14 0 0 0 2.04E+07 4.22E+06 - - - 4.7936 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19225.19225.2 0.0156 16-Jun R.YVALTSLLK.T sp|O43747|AP1G1_HUMAN 1 1006.6063 1.62 33389 19225 2 1006.60854 504.3104 AP-1 complex subunit gamma-1 OS=Homo sapiens OX=9606 GN=AP1G1 PE=1 SV=5 8.59 3659.9 - 4.39E+06 - - - 2.2422 - 1.284 0.462 - 78.9 1 2 0 0.0023 9 0 0 0 1.13E+07 6.99E+06 - - - 3.1758 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19226.19226.2 0.0215 14-Jul K.GLLDVLPK.N "sp|O95071|UBR5_HUMAN,tr|E7ET84|E7ET84_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 853.5273 2.45 33390 19226 2 853.52888 427.7709 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.84 3659.9 - 3.35E+06 - - - 1.8465 - 1.462 0.336 - 144.9 1 2 0 0.0016 8 0 0 0 1.66E+07 6.78E+06 - - - 2.6677 0.9941 230117_WJC_METTL3_WT_vs_EV_F04.19228.19228.2 1.8 16-Aug K.GVILLIVDK.A "sp|P78344|IF4G2_HUMAN,tr|H0YE44|H0YE44_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 8 968.627 1.78 33392 19228 2 968.629322 485.3208 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.84 3660 - 2.91E+06 - - - 2.3786 - 1.584 0.092 - 139.9 1 2 0 0.0023 9 0 0 0 1.07E+07 6.00E+06 - - - 1.0505 0.8666 230117_WJC_METTL3_WT_vs_EV_F04.19229.19229.2 3.63 16-May R.YVALTSLLK[136.11].T sp|O43747|AP1G1_HUMAN 1 1014.6205 1.62 33393 19229 2 1014.623299 508.3175 AP-1 complex subunit gamma-1 OS=Homo sapiens OX=9606 GN=AP1G1 PE=1 SV=5 8.59 3660.1 - 2.70E+06 - - - 2.7754 - 0.829 0.073 - 54.1 1 2 0 0.0028 9 0 0 0 1.13E+07 6.99E+06 - - - -0.9633 0.9824 230117_WJC_METTL3_WT_vs_EV_F04.19232.19232.2 0.841 14-May R.ILPWSTFR[166.11].L "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1028.5683 0.66 33396 19232 2 1028.570213 515.2914 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3660.3 - 1.66E+06 - - - 1.8871 - 1.038 0.133 - 86.6 1 2 0 0.0019 8 0 0 0 7.50E+06 1.13E+07 - - - 0.1352 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19233.19233.2 0.0149 16-Aug K.GVILLIVDK[136.11].A "sp|P78344|IF4G2_HUMAN,tr|H0YE44|H0YE44_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 8 976.6412 1.78 33397 19233 2 976.643393 489.3279 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.84 3660.3 - 1.49E+06 - - - 2.227 - 1.541 0.382 - 143.1 1 2 0 0.0022 9 0 0 0 1.07E+07 6.00E+06 - - - 3.1128 1 230117_WJC_METTL3_WT_vs_EV_F04.19235.19235.2 0.00194 13/26 R.WSSLAC[160.03]NIALDAVK.M "sp|P49368|TCPG_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1546.7814 999 33399 19235 2 1546.786735 774.398 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.83 3660.5 - 1.40E+06 - - - 3.4724 - 2.44 0.481 - 430 1 2 0 0.0054 14 0 0 0 3.26E+06 0.00E+00 - - - 4.8304 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19236.19236.2 0.000108 18-Jul R.SIPMTVDFIR[166.11].L sp|P00492|HPRT_HUMAN 1 1187.6248 2.08 33400 19236 2 1187.627306 594.8197 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 5.55 3660.5 - 1.39E+06 - - - 2.1101 - 1.749 0.435 - 148.7 1 2 0 0.0025 10 0 0 0 1.54E+07 7.39E+06 - - - 3.8136 1 230117_WJC_METTL3_WT_vs_EV_F04.19239.19239.2 0.000931 20-Oct K.ELLDTELDLYK[136.11].K "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1358.7061 1.31 33403 19239 2 1358.707369 680.3603 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 3.92 3660.9 - 684358 - - - 0.9612 - 2.36 0.462 - 306.3 1 2 0 0.0013 11 0 0 0 3.62E+06 2.76E+06 - - - 4.7758 1 230117_WJC_METTL3_WT_vs_EV_F04.19243.19243.2 6.30E-08 14/24 R.IITLTGPTNAIFK.A sp|Q15365|PCBP1_HUMAN 1 1387.8075 3.52 33405 19243 2 1387.811872 694.911 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3661.5 - 6.33E+06 - - - 3.1489 - 2.714 0.53 - 571.3 1 2 0 0.0044 13 0 0 0 1.61E+08 4.59E+07 - - - 5.5167 1 230117_WJC_METTL3_WT_vs_EV_F04.19244.19244.2 0.00132 14/22 K.ATGILLYGLASR.L "sp|P47897|SYQ_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|F2Z2V6|F2Z2V6_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 9 1233.7081 1.5 33406 19244 2 1233.714821 617.8613 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 8.79 3661.6 - 2.57E+06 - - - 5.43 - 2.501 0.435 - 793.2 1 2 0 0.0067 12 0 0 0 1.82E+07 1.22E+07 - - - 4.6638 1 230117_WJC_METTL3_WT_vs_EV_F04.19245.19245.2 2.08E-08 20-Nov R.FFDEESYSLLR.K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1404.6561 1.59 33407 19245 2 1404.659042 703.3353 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3661.6 - 3.98E+06 - - - 2.0617 - 2.431 0.588 - 259.1 1 2 0 0.0029 11 0 0 0 6.10E+07 3.82E+07 - - - 5.7861 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19247.19247.2 1.11 16-Sep R.VLEALLPLK.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 994.6427 1.69 33409 19247 2 994.645189 498.3286 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3661.8 - 1.87E+06 - - - 2.5336 - 1.965 0.287 - 269.8 1 2 0 0.0025 9 0 0 0 8.44E+07 4.99E+07 - - - 3.1142 0.9848 230117_WJC_METTL3_WT_vs_EV_F04.19248.19248.2 1.79 14-Jun R.QWELLLEK.M "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SFF6|A0A0D9SFF6_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN,tr|A0A5F9ZHC3|A0A5F9ZHC3_HUMAN" 5 1057.5808 0.87 33410 19248 2 1057.582364 529.7977 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 3661.9 - 1.84E+06 - - - 1.4817 - 1.335 0.037 - 157.3 1 2 0 0.0016 8 0 0 0 1.12E+07 1.29E+07 - - - 0.1852 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19249.19249.2 0.001 24-Aug R.IITLTGPTNAIFK[136.11].A sp|Q15365|PCBP1_HUMAN 1 1395.8217 3.52 33411 19249 2 1395.824787 698.9181 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3662 - 1.82E+06 - - - 2.2102 - 1.979 0.345 - 166.9 1 2 0 0.0031 13 0 0 0 1.61E+08 4.59E+07 - - - 3.3401 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19250.19250.2 0.0137 14-Jul K.LFVGFLNR.A "sp|Q9NXE4|NSMA3_HUMAN,tr|H7C0W5|H7C0W5_HUMAN,tr|H7C2E2|H7C2E2_HUMAN,tr|H7C2J2|H7C2J2_HUMAN,tr|H7C1Q6|H7C1Q6_HUMAN,tr|H7C235|H7C235_HUMAN,tr|A0A7P0TB44|A0A7P0TB44_HUMAN,tr|A0A7P0T9J6|A0A7P0T9J6_HUMAN,tr|A0A7P0TB24|A0A7P0TB24_HUMAN" 9 964.5494 1.97 33412 19250 2 964.552272 483.282 Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3 9.75 3662 - 1.60E+06 - - - 2.9392 - 1.534 0.434 - 189.1 1 2 0 0.0028 8 0 0 0 1.16E+07 5.86E+06 - - - 3.5361 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.19251.19251.2 0.0386 14-Jul K.LFVGFLNR[166.11].A "sp|Q9NXE4|NSMA3_HUMAN,tr|H7C0W5|H7C0W5_HUMAN,tr|H7C2E2|H7C2E2_HUMAN,tr|H7C2J2|H7C2J2_HUMAN,tr|H7C1Q6|H7C1Q6_HUMAN,tr|H7C235|H7C235_HUMAN,tr|A0A7P0TB44|A0A7P0TB44_HUMAN,tr|A0A7P0T9J6|A0A7P0T9J6_HUMAN,tr|A0A7P0TB24|A0A7P0TB24_HUMAN" 9 974.5577 1.95 33413 19251 2 974.56217 488.2861 Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3 9.75 3662.1 - 1.08E+06 - - - 4.5795 - 1.477 0.33 - 134.3 1 2 0 0.0045 8 0 0 0 1.14E+07 5.86E+06 - - - 2.6532 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19254.19254.2 0.802 15/24 K.LGLSLVVPGGGIK.K sp|Q99747|SNAG_HUMAN 1 1208.7493 3.52 33416 19254 2 1208.751922 605.3819 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3662.5 - 655080 - - - 2.2031 - 2.753 0.321 - 536.6 1 2 0 0.0027 13 0 0 0 8.07E+06 2.29E+06 - - - 4.0102 1 230117_WJC_METTL3_WT_vs_EV_F04.19256.19256.3 7.92E-08 13/44 R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 0.85 33418 19256 3 1315.789819 439.6027 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3662.7 - 497758 - - - 2.619 - 2.405 0.554 - 199.8 1 2 0 0.0034 12 0 0 0 1.75E+07 2.05E+07 - - - 7.148 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19263.19263.2 0.000756 18-Aug R.SIPMTVDFIR.L sp|P00492|HPRT_HUMAN 1 1177.6165 1.93 33424 19263 2 1177.617832 589.8155 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 5.55 3663.5 - 644308 - - - 1.1056 - 1.769 0.313 - 176.7 1 2 0 0.0013 10 0 0 0 1.54E+07 8.00E+06 - - - 2.9446 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.19264.19264.2 0.161 12-Jul R.LWAELLR.T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN" 3 899.5229 1.36 33425 19264 2 899.524613 450.7687 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 6 3663.7 - 575835 - - - 1.9177 - 1.497 0.192 - 157.5 1 2 0 0.0017 7 0 0 0 5.47E+06 4.02E+06 - - - 1.737 1 230117_WJC_METTL3_WT_vs_EV_F04.19265.19265.2 1.55E-11 13/20 R.FFDEESYSLLR[166.11].K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1414.6644 1.59 33426 19265 2 1414.665452 708.3395 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3663.7 - 8.14E+06 - - - 0.7323 - 2.653 0.47 - 418 1 2 0 0.001 11 0 0 0 6.10E+07 3.82E+07 - - - 5.1516 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19266.19266.2 0.125 16-Nov R.VLEALLPLK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1002.6569 1.69 33427 19266 2 1002.657956 502.3357 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3663.8 - 4.87E+06 - - - 1.0841 - 2.008 0.371 - 474.6 1 2 0 0.0011 9 0 0 0 8.44E+07 4.99E+07 - - - 3.7977 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.19267.19267.3 0.0051 Aug-44 R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.08 33428 19267 3 1323.801683 442.2741 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3663.8 - 3.32E+06 - - - 0.8385 - 1.764 0.393 - 85.1 1 2 0 0.0011 12 0 0 0 1.73E+07 1.61E+07 - - - 4.4945 0.9064 230117_WJC_METTL3_WT_vs_EV_F04.19268.19268.2 0.072 14-Jun K.NALESYAF.N "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 913.4181 - 33429 19268 2 913.418948 457.7164 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4 3663.9 - 2.44E+06 - - - 0.8758 - 1.25 0.332 - 122.6 1 1 0 0.0008 8 0 0 0 - - - - - 2.1659 1 230117_WJC_METTL3_WT_vs_EV_F04.19270.19270.2 0.00016 18-Dec R.LGLDDFESLK[136.11].V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1143.5903 0.41 33431 19270 2 1143.593875 572.8024 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3664.1 - 1.34E+06 - - - 3.1217 - 2.323 0.481 - 326.5 1 2 0 0.0036 10 0 0 0 4.12E+07 9.98E+07 - - - 4.9452 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19274.19274.2 0.589 24-Dec K.LGLSLVVPGGGIK[136.11].K sp|Q99747|SNAG_HUMAN 1 1216.7635 3.52 33435 19274 2 1216.765242 609.389 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3664.5 - 715127 - - - 1.4654 - 1.988 0.284 - 259.7 1 2 0 0.0018 13 0 0 0 8.07E+06 2.29E+06 - - - 2.9016 0.999 230117_WJC_METTL3_WT_vs_EV_F04.19285.19285.2 0.0137 14-Aug K.LVYVDLLR.E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 989.591 1.87 33445 19285 2 989.593809 495.8028 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.84 3665.9 - 1.16E+06 - - - 2.8719 - 1.485 0.377 - 186.6 1 2 0 0.0028 8 0 0 0 3.05E+07 1.64E+07 - - - 3.0172 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.19292.19292.2 3.65E-05 22-Dec R.NIPGITLLNVSK[136.11].L "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1275.7642 0.96 33452 19292 2 1275.76256 638.8894 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.75 3666.8 - 311011 - - - -1.2753 - 1.892 0.262 - 348.5 1 2 0 -0.0016 12 0 0 0 1.71E+06 1.78E+06 - - - 2.6533 1 230117_WJC_METTL3_WT_vs_EV_F04.19294.19294.2 0.0511 18-Oct R.LGLDDFESLK.V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1135.5761 0.41 33453 19294 2 1135.577263 568.7953 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3667 - 1.27E+06 - - - 1.0197 - 2.289 0.483 - 202.2 1 2 0 0.0012 10 0 0 0 4.12E+07 9.98E+07 - - - 4.9196 1 230117_WJC_METTL3_WT_vs_EV_F04.19296.19296.2 0.000209 16-Nov K.LPFPIIDDR[166.11].N sp|P30041|PRDX6_HUMAN 1 1094.6 1.28 33455 19296 2 1094.601118 548.3073 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.21 3667.3 - 1.03E+06 - - - 1.0524 - 2.195 0.443 - 620.7 1 2 0 0.0012 9 0 0 0 7.00E+07 5.46E+07 - - - 4.5871 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19302.19302.2 0.00311 16-Oct K.TLEEILLER.A "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 3 1114.6234 1.37 33461 19302 2 1114.623891 558.319 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.25 3668.1 - 358029 - - - 0.4495 - 2.064 0.39 - 300.6 1 2 0 0.0005 9 0 0 0 4.73E+07 3.46E+07 - - - 4.0178 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19307.19307.2 0.0255 16-Sep K.LSPEELLLR.W "sp|P13797|PLST_HUMAN,sp|Q14651|PLSI_HUMAN,sp|P13796|PLSL_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|C9JAM8|C9JAM8_HUMAN" 5 1068.6179 2.79 33464 19307 2 1068.618833 535.3162 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.53 3668.7 - 2.43E+06 - - - 0.8637 - 1.704 0.302 - 175.9 1 2 0 0.0009 9 0 0 0 3.23E+07 1.16E+07 - - - 2.8132 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19308.19308.2 0.00151 20-Oct R.LLGLGVTDFSR[166.11].A "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 1186.6585 0.66 33465 19308 2 1186.659808 594.3365 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 5.84 3668.9 - 1.47E+06 - - - 1.066 - 2.379 0.395 - 283.9 1 2 0 0.0013 11 0 0 0 6.42E+06 9.77E+06 - - - 4.3026 0.9957 230117_WJC_METTL3_WT_vs_EV_F04.19311.19311.2 0.0214 18-Jul R.FLVPIESIER[166.11].A sp|Q14249|NUCG_HUMAN 1 1211.6789 4.07 33468 19311 2 1211.685378 606.8467 "Endonuclease G, mitochondrial OS=Homo sapiens OX=9606 GN=ENDOG PE=1 SV=4" 4.53 3669.3 - 801871 - - - 5.31 - 1.787 0.346 - 154.2 1 2 0 0.0064 10 0 0 0 1.66E+07 4.08E+06 - - - 3.215 0.9679 230117_WJC_METTL3_WT_vs_EV_F04.19312.19312.2 0.422 16-Jul K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 5.69 33469 19312 2 1014.539845 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3669.4 - 744317 - - - 5.1945 - 1.671 0.099 - 112.8 2 2 0 0.0053 9 0 0 0 7.69E+06 1.35E+06 - - - 1.1214 1 230117_WJC_METTL3_WT_vs_EV_F04.19314.19314.2 6.11E-05 14/24 R.TPFTTAQLLALER.K sp|P28360|MSX1_HUMAN 1 1459.8035 1.57 33471 19314 2 1459.805676 730.909 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3669.6 - 566323 - - - 1.505 - 2.706 0.531 - 613.5 1 2 0 0.0022 13 0 0 0 8.97E+06 5.70E+06 - - - 5.5172 0.9903 230117_WJC_METTL3_WT_vs_EV_F04.19316.19316.2 0.327 14-Jun K.GVLSDLTK.V "sp|Q8NG11|TSN14_HUMAN,tr|A6NEP9|A6NEP9_HUMAN,tr|H7BXY6|H7BXY6_HUMAN" 3 831.4702 11.21 33473 19316 2 831.469035 416.7424 Tetraspanin-14 OS=Homo sapiens OX=9606 GN=TSPAN14 PE=1 SV=1 5.84 3669.9 - 408571 - - - -1.3807 - 1.445 0.172 - 111.6 1 2 0 -0.0011 8 0 0 0 5.95E+06 5.31E+05 - - - 1.4212 1 230117_WJC_METTL3_WT_vs_EV_F04.19317.19317.2 1.86E-06 15/24 R.TPFTTAQLLALER[166.11].K sp|P28360|MSX1_HUMAN 1 1469.8117 1.57 33474 19317 2 1469.815021 735.9132 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3670 - 384620 - - - 2.2261 - 3.08 0.585 - 790 1 2 0 0.0033 13 0 0 0 8.97E+06 5.70E+06 - - - 6.2479 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.19318.19318.2 0.136 18-Aug R.LLLQIPSTIR[166.11].S sp|Q16394|EXT1_HUMAN 1 1162.7313 1.11 33475 19318 2 1162.732842 582.3729 Exostosin-1 OS=Homo sapiens OX=9606 GN=EXT1 PE=1 SV=2 9.75 3670.2 - 317981 - - - 1.3141 - 1.736 0.144 - 180 1 2 0 0.0015 10 0 0 0 2.86E+06 2.58E+06 - - - 1.6437 0.9609 230117_WJC_METTL3_WT_vs_EV_F04.19324.19324.2 5.02 16-Jul K.LSPEELLLR[166.11].W "sp|P13797|PLST_HUMAN,sp|Q14651|PLSI_HUMAN,sp|P13796|PLSL_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|C9JAM8|C9JAM8_HUMAN" 5 1078.6262 2.74 33479 19324 2 1078.62939 540.3204 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.53 3671 - 736719 - - - 2.976 - 1.274 0.045 - 73.2 2 2 0 0.0032 9 0 0 0 3.07E+07 1.12E+07 - - - -0.0615 0.9962 230117_WJC_METTL3_WT_vs_EV_F04.19325.19325.2 1.02 12-Jun M.GLLSILR.K "sp|P36405|ARL3_HUMAN,sp|Q14517|FAT1_HUMAN,tr|A0A087WVP1|A0A087WVP1_HUMAN" 3 770.5014 1.55 33480 19325 2 770.5029 386.258 ADP-ribosylation factor-like protein 3 OS=Homo sapiens OX=9606 GN=ARL3 PE=1 SV=2 9.75 3671.1 - 723739 - - - 1.9156 - 1.324 0.177 - 119.7 1 2 0 0.0015 7 0 0 0 4.43E+06 2.85E+06 - - - 1.2371 0.9909 230117_WJC_METTL3_WT_vs_EV_F04.19326.19326.2 0.772 18-Jun R.LLLQIPSTIR.S sp|Q16394|EXT1_HUMAN 1 1152.723 1.11 33481 19326 2 1152.725245 577.3688 Exostosin-1 OS=Homo sapiens OX=9606 GN=EXT1 PE=1 SV=2 9.75 3671.3 - 476495 - - - 1.9094 - 1.387 0.115 - 86.5 3 2 0 0.0022 10 0 0 0 2.86E+06 2.58E+06 - - - 0.5897 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19330.19330.2 0.00797 12-Sep R.SGMFWLR.F sp|P31930|QCR1_HUMAN 1 895.4374 1.14 33485 19330 2 895.439602 448.726 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 9.47 3671.8 - 343318 - - - 2.41 - 1.813 0.37 - 365.3 1 2 0 0.0022 7 0 0 0 3.60E+06 3.17E+06 - - - 3.6584 1 230117_WJC_METTL3_WT_vs_EV_F04.19338.19338.2 0.00019 15/24 R.ILDIDNVDLAMGK.M sp|O43615|TIM44_HUMAN 1 1415.733 2.75 33491 19338 2 1415.735298 708.8738 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3672.8 - 1.16E+06 - - - 1.6112 - 2.802 0.567 - 720.7 1 2 0 0.0023 13 0 0 0 8.73E+06 3.17E+06 - - - 5.8725 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19339.19339.2 0.00294 16-Oct K.IPSVLFLGK.L sp|Q8IW75|SPA12_HUMAN 1 972.6008 206.25 33492 19339 2 972.603061 487.3077 Serpin A12 OS=Homo sapiens OX=9606 GN=SERPINA12 PE=1 SV=1 8.75 3672.9 - 646238 - - - 2.3206 - 1.95 0.397 - 230.8 1 2 0 0.0023 9 0 0 0 3.98E+06 1.93E+04 - - - 3.9046 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.19340.19340.2 0.0162 18-Nov R.LTC[160.03]LGVWLDK[136.11].V sp|Q9NWT1|PK1IP_HUMAN 1 1211.6464 0.97 33493 19340 2 1211.645401 606.8305 p21-activated protein kinase-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAK1IP1 PE=1 SV=2 5.83 3673.1 - 595345 - - - -0.8088 - 2.147 0.266 - 359.1 1 2 0 -0.001 10 0 0 0 2.22E+06 2.28E+06 - - - 3.1381 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.19341.19341.2 0.107 22-Sep R.GILLFGPPGTGK.S "sp|Q9UN37|VPS4A_HUMAN,sp|O75351|VPS4B_HUMAN,sp|Q6PIW4|FIGL1_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 4 1155.6652 6.32 33494 19341 2 1155.668522 578.8399 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 8.75 3673.2 - 525811 - - - 2.8789 - 1.954 0.261 - 171.2 1 2 0 0.0033 12 0 0 0 4.73E+06 7.48E+05 - - - 2.7303 0.9767 230117_WJC_METTL3_WT_vs_EV_F04.19342.19342.2 0.447 14-Jul K.ELEPFLLR[166.11].R sp|O14646|CHD1_HUMAN 1 1025.5785 0.63 33495 19342 2 1025.583246 513.7965 Chromodomain-helicase-DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=CHD1 PE=1 SV=2 4.53 3673.3 - 495618 - - - 4.6257 - 1.456 0.122 - 214.5 1 2 0 0.0047 8 0 0 0 1.93E+06 3.07E+06 - - - 1.0737 1 230117_WJC_METTL3_WT_vs_EV_F04.19343.19343.2 0.00146 13/24 R.ILDIDNVDLAMGK[136.11].M sp|O43615|TIM44_HUMAN 1 1423.7472 2.75 33496 19343 2 1423.74862 712.8809 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3673.5 - 434306 - - - 0.9854 - 2.603 0.482 - 531.7 1 2 0 0.0014 13 0 0 0 8.73E+06 3.17E+06 - - - 5.0559 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.19345.19345.2 0.0477 12-Jun R.SGMFWLR[166.11].F sp|P31930|QCR1_HUMAN 1 905.4457 1.17 33498 19345 2 905.447903 453.7301 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 9.47 3673.7 - 401310 - - - 2.4176 - 1.559 0.262 - 131.9 1 2 0 0.0022 7 0 0 0 3.60E+06 3.09E+06 - - - 2.3824 1 230117_WJC_METTL3_WT_vs_EV_F04.19353.19353.2 4.42E-07 15/22 K.YDAFLASESLIK[136.11].Q sp|P62906|RL10A_HUMAN 1 1363.7115 0.87 33505 19353 2 1363.71558 682.863 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.37 3674.7 - 2.41E+06 - - - 3.0043 - 2.729 0.55 - 710.2 1 2 0 0.0041 12 0 0 0 2.03E+07 2.34E+07 - - - 5.7435 1 230117_WJC_METTL3_WT_vs_EV_F04.19356.19356.2 9.06E-08 15/24 R.IITLAGPTNAIFK.A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1357.7969 2.76 33508 19356 2 1357.801277 679.9057 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3674.9 - 2.29E+06 - - - 3.1964 - 2.771 0.592 - 749.1 1 2 0 0.0043 13 0 0 0 2.36E+08 8.54E+07 - - - 6.028 0.9932 230117_WJC_METTL3_WT_vs_EV_F04.19357.19357.2 6.19E-05 16-Aug K.DVDLEFLAK[136.11].M "sp|P55072|TERA_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN" 6 1056.5583 0.86 33509 19357 2 1056.564636 529.2864 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.03 3675 - 1.26E+06 - - - 6.0186 - 1.723 0.358 - 150 1 2 0 0.0064 9 0 0 0 5.82E+06 6.76E+06 - - - 3.2572 0.9867 230117_WJC_METTL3_WT_vs_EV_F04.19358.19358.2 0.7 14-Sep R.LPLFGLGR[166.11].L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 881.5362 1.39 33510 19358 2 881.539562 441.7754 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3675.1 - 778134 - - - 3.765 - 1.633 0.073 - 380 1 2 0 0.0033 8 0 0 0 1.17E+08 8.38E+07 - - - 1.0582 0.9927 230117_WJC_METTL3_WT_vs_EV_F04.19360.19360.2 0.45 14-Oct R.LPLFGLGR.L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 871.528 1.39 33512 19360 2 871.531166 436.7713 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3675.4 - 589194 - - - 3.6637 - 1.588 0.143 - 432.1 1 2 0 0.0032 8 0 0 0 1.17E+08 8.38E+07 - - - 1.491 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19361.19361.2 0.0309 20-Nov K.ILEAVTLVQLK[136.11].E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1233.7788 0.81 33513 19361 2 1233.782869 617.8967 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6 3675.5 - 437201 - - - 3.3183 - 2.394 0.38 - 259.9 1 2 0 0.0041 11 0 0 0 2.08E+06 2.55E+06 - - - 4.208 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19362.19362.2 0.184 16-Oct K.WQALLVQIR[166.11].K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1135.6741 1.29 33514 19362 2 1135.67688 568.8443 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.75 3675.6 - 360965 - - - 2.4179 - 2 0.284 - 321.3 1 2 0 0.0027 9 0 0 0 6.47E+06 5.01E+06 - - - 3.1431 0.998 230117_WJC_METTL3_WT_vs_EV_F04.19364.19364.2 0.0559 16-Aug R.VVVLGLLPR.G "sp|Q15102|PA1B3_HUMAN,tr|M0R389|M0R389_HUMAN" 2 964.6433 1.47 33516 19364 2 964.646775 483.3289 Platelet-activating factor acetylhydrolase IB subunit alpha1 OS=Homo sapiens OX=9606 GN=PAFAH1B3 PE=1 SV=1 9.72 3675.9 - 208856 - - - 3.564 - 1.887 0.248 - 221 1 2 0 0.0034 9 0 0 0 1.64E+06 1.11E+06 - - - 2.7087 1 230117_WJC_METTL3_WT_vs_EV_F04.19366.19366.2 1.14E-07 13/26 R.WTTEEQLLAVQAIR.K sp|Q9UKL0|RCOR1_HUMAN 1 1656.8835 -1 33518 19366 2 1656.885345 829.449 REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2 4.53 3676.1 - 143209 - - - 1.1009 - 2.844 0.585 - 650.8 1 2 0 0.0018 14 0 0 0 0.00E+00 0.00E+00 - - - 5.9841 0.9928 230117_WJC_METTL3_WT_vs_EV_F04.19373.19373.2 0.0444 12-Jul K.LYSLLFR[166.11].R sp|Q9UDW1|QCR9_HUMAN 1 920.5359 1.23 33524 19373 2 920.539657 461.2752 Cytochrome b-c1 complex subunit 9 OS=Homo sapiens OX=9606 GN=UQCR10 PE=1 SV=3 8.75 3677.2 - 1.51E+06 - - - 4.0715 - 1.489 0.194 - 178.6 1 2 0 0.0037 7 0 0 0 4.58E+06 3.72E+06 - - - 1.7341 1 230117_WJC_METTL3_WT_vs_EV_F04.19374.19374.2 0.000318 20-Nov K.LGGNEIVSFLK.G "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 4 1175.655 6.33 33525 19374 2 1176.661166 588.8348 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6 3677.3 - 1.09E+06 - - - 855.814 - 2.636 0.441 - 317.9 1 2 0 1.0061 11 0 0 0 1.65E+07 2.61E+06 - - - 4.6044 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19375.19375.2 0.000572 13/24 R.IITLAGPTNAIFK[136.11].A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1365.8111 2.76 33526 19375 2 1365.814612 683.9128 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3677.3 - 9.19E+06 - - - 2.5443 - 2.405 0.42 - 512.3 1 2 0 0.0035 13 0 0 0 2.36E+08 8.54E+07 - - - 4.3943 1 230117_WJC_METTL3_WT_vs_EV_F04.19376.19376.2 8.01E-06 20-Dec K.VGEVTYVELFK.D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1282.6809 1.83 33527 19376 2 1282.686625 642.3477 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.53 3677.4 - 6.88E+06 - - - 4.4594 - 2.527 0.483 - 605.5 1 2 0 0.0057 11 0 0 0 3.89E+07 2.13E+07 - - - 5.1145 1 230117_WJC_METTL3_WT_vs_EV_F04.19378.19378.2 0.000151 16-Oct K.WQALLVQIR.K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1125.6659 1.26 33529 19378 2 1125.670616 563.8402 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.75 3677.6 - 1.52E+06 - - - 4.2215 - 2.049 0.471 - 416.3 1 2 0 0.0048 9 0 0 0 6.47E+06 5.12E+06 - - - 4.5937 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.19379.19379.2 0.00118 20-Nov K.LWDLASGTLYK.E sp|O75529|TAF5L_HUMAN 1 1265.6656 1.37 33530 19379 2 1265.670705 633.8401 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 5.83 3677.7 - 1.52E+06 - - - 4.0421 - 1.928 0.427 - 395.4 1 2 0 0.0051 11 0 0 0 6.20E+06 4.52E+06 - - - 3.9692 1 230117_WJC_METTL3_WT_vs_EV_F04.19380.19380.2 1.11E-05 13/20 K.LWDLASGTLYK[136.11].E sp|O75529|TAF5L_HUMAN 1 1273.6798 1.39 33531 19380 2 1273.686302 637.8472 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 5.83 3677.8 - 1.32E+06 - - - 5.1135 - 2.439 0.571 - 584.7 1 2 0 0.0065 11 0 0 0 6.29E+06 4.52E+06 - - - 5.6683 0.9919 230117_WJC_METTL3_WT_vs_EV_F04.19381.19381.2 0.00443 18-Oct K.SLLFVNTLER[166.11].S "sp|Q9NY93|DDX56_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1200.6742 0.29 33532 19381 2 1200.681732 601.3444 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 5.72 3678 - 1.01E+06 - - - 6.279 - 2.11 0.289 - 306.3 1 2 0 0.0075 10 0 0 0 3.93E+06 1.38E+07 - - - 3.2574 1 230117_WJC_METTL3_WT_vs_EV_F04.19382.19382.2 0.00786 13/22 K.LILISTNGSFIR.L sp|Q6UXN9|WDR82_HUMAN 1 1332.7765 0.92 33533 19382 2 1332.784235 667.3955 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 9.75 3678.1 - 932585 - - - 5.7767 - 2.532 0.447 - 573.3 1 2 0 0.0077 12 0 0 0 3.96E+06 4.29E+06 - - - 4.7845 0.9758 230117_WJC_METTL3_WT_vs_EV_F04.19383.19383.2 2.12 26-Jul K.VVIGMDVAASEFYR.N "sp|P13929|ENOB_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN" 2 1555.7705 2.03 33534 19383 2 1555.773802 778.8925 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.37 3678.2 - 929821 - - - 2.1449 - 1.051 0.11 - 102 1 2 0 0.0033 14 0 0 0 2.54E+07 1.25E+07 - - - -0.0228 0.998 230117_WJC_METTL3_WT_vs_EV_F04.19384.19384.2 0.00382 22-Dec K.LILISTNGSFIR[166.11].L sp|Q6UXN9|WDR82_HUMAN 1 1342.7848 0.92 33535 19384 2 1342.791501 672.3997 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 9.75 3678.4 - 919335 - - - 4.9859 - 2.354 0.39 - 408.4 1 2 0 0.0067 12 0 0 0 3.96E+06 4.29E+06 - - - 4.172 1 230117_WJC_METTL3_WT_vs_EV_F04.19385.19385.2 5.30E-06 14/20 K.ILEAVTLVQLK.E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1225.7646 -1 33536 19385 2 1225.770332 613.8896 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6 3678.5 - 917410 - - - 4.6967 - 2.8 0.422 - 516.4 1 2 0 0.0058 11 0 0 0 0.00E+00 0.00E+00 - - - 4.9414 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.19386.19386.2 0.0549 16-Sep R.MADLSELLK.E "sp|P30519|HMOX2_HUMAN,tr|I3L276|I3L276_HUMAN,tr|I3L159|I3L159_HUMAN,tr|I3L463|I3L463_HUMAN,tr|I3L4P8|I3L4P8_HUMAN,tr|A0A1B0GXH0|A0A1B0GXH0_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 8 1018.5369 1.8 33537 19386 2 1018.540822 510.2757 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 4.37 3678.6 - 837015 - - - 3.8673 - 1.763 0.221 - 223.5 1 2 0 0.0039 9 0 0 0 3.35E+06 1.86E+06 - - - 2.3125 1 230117_WJC_METTL3_WT_vs_EV_F04.19387.19387.2 6.30E-06 20-Nov K.LGGNEIVSFLK[136.11].G "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 4 1183.6692 6.46 33538 19387 2 1183.673882 592.8419 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6 3678.8 - 772708 - - - 3.9352 - 2.408 0.521 - 258.7 1 2 0 0.0047 11 0 0 0 1.72E+07 2.66E+06 - - - 5.265 1 230117_WJC_METTL3_WT_vs_EV_F04.19389.19389.2 0.000524 22-Nov K.LFGYEPTIYYPK[136.11].R "sp|Q8NCW5|NNRE_HUMAN,tr|A0A7P0Z426|A0A7P0Z426_HUMAN,tr|Q5T3I4|Q5T3I4_HUMAN,tr|A0A7P0T9Y2|A0A7P0T9Y2_HUMAN,tr|A0A7P0TAG8|A0A7P0TAG8_HUMAN,tr|Q5T3I3|Q5T3I3_HUMAN" 6 1497.7635 1.65 33540 19389 2 1497.769769 749.889 NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2 6 3679 - 614535 - - - 4.1729 - 2.226 0.49 - 262.4 1 2 0 0.0063 12 0 0 0 4.43E+06 2.69E+06 - - - 4.7637 0.9823 230117_WJC_METTL3_WT_vs_EV_F04.19391.19391.2 0.618 16-Aug R.MADLSELLK[136.11].E "sp|P30519|HMOX2_HUMAN,tr|I3L276|I3L276_HUMAN,tr|I3L159|I3L159_HUMAN,tr|I3L463|I3L463_HUMAN,tr|I3L4P8|I3L4P8_HUMAN,tr|A0A1B0GXH0|A0A1B0GXH0_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 8 1026.5511 1.8 33542 19391 2 1026.554887 514.2828 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 4.37 3679.3 - 581196 - - - 3.7056 - 1.429 0.1 - 98 1 2 0 0.0038 9 0 0 0 3.35E+06 1.86E+06 - - - 0.8112 1 230117_WJC_METTL3_WT_vs_EV_F04.19392.19392.2 0.000309 22-Nov K.QVVPFVYQTIVK[136.11].D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1427.8268 -1 33543 19392 2 1427.831048 714.9207 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 3679.4 - 571649 - - - 2.9836 - 2.118 0.494 - 298.9 1 2 0 0.0043 12 0 0 0 0.00E+00 0.00E+00 - - - 4.663 0.9847 230117_WJC_METTL3_WT_vs_EV_F04.19395.19395.2 0.361 12-Jul K.FDLIWNR.A "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|H0YEW4|H0YEW4_HUMAN,tr|A8MRA7|A8MRA7_HUMAN,tr|H0YD21|H0YD21_HUMAN" 5 962.4974 2.55 33545 19395 2 962.501446 482.256 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 5.84 3679.7 - 774433 - - - 4.2026 - 1.747 0.069 - 203.6 2 2 0 0.004 7 0 0 0 2.23E+06 8.76E+05 - - - 1.1826 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.19397.19397.2 0.151 16-Aug K.NLLNLDVIK.K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1040.623 1.03 33547 19397 2 1040.62525 521.3188 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3679.8 - 2.11E+06 - - - 2.166 - 1.74 0.218 - 199 1 2 0 0.0023 9 0 0 0 1.83E+07 1.77E+07 - - - 2.2529 0.999 230117_WJC_METTL3_WT_vs_EV_F04.19398.19398.2 0.0154 16-Sep K.NLLNLDVIK[136.11].K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1048.6372 1.03 33548 19398 2 1048.640662 525.3259 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3679.9 - 1.97E+06 - - - 3.3052 - 1.927 0.328 - 251 1 2 0 0.0035 9 0 0 0 1.83E+07 1.77E+07 - - - 3.3603 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.19399.19399.2 0.494 14-Jul R.EMVLEIIR[166.11].E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1011.5662 2.11 33549 19399 2 1011.568453 506.7904 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3679.9 - 1.75E+06 - - - 2.2045 - 1.552 0.172 - 241.3 1 2 0 0.0022 8 0 0 0 1.76E+07 8.37E+06 - - - 1.6363 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19400.19400.2 0.0179 14-Sep R.LWDFIENR.E "sp|Q9H000|MKRN2_HUMAN,tr|A0A7I2V5D2|A0A7I2V5D2_HUMAN,tr|A0A7I2YQI0|A0A7I2YQI0_HUMAN,tr|C9J494|C9J494_HUMAN" 4 1091.54 2.41 33550 19400 2 1091.541668 546.7773 Probable E3 ubiquitin-protein ligase makorin-2 OS=Homo sapiens OX=9606 GN=MKRN2 PE=1 SV=2 4.37 3680 - 1.54E+06 - - - 1.5336 - 2.023 0.346 - 312.7 1 2 0 0.0017 8 0 0 0 8.53E+06 3.54E+06 - - - 3.721 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19402.19402.2 0.0128 22-Jul K.QVVPFVYQTIVK.D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1419.8126 -1 33552 19402 2 1419.814022 710.9136 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 3680.1 - 891698 - - - 1.01 - 1.722 0.348 - 146 1 2 0 0.0014 12 0 0 0 0.00E+00 0.00E+00 - - - 3.0409 1 230117_WJC_METTL3_WT_vs_EV_F04.19403.19403.2 5.79E-08 17/26 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 3.5 33553 19403 2 1541.84945 771.9299 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3680.2 - 854258 - - - 2.663 - 2.999 0.492 - 1101.7 1 2 0 0.0041 14 0 0 0 1.23E+08 3.52E+07 - - - 5.4297 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19406.19406.2 0.0104 24-Nov R.VESPVLPPVLVPR.H "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN" 2 1400.8391 2.12 33556 19406 2 1400.842479 701.4268 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 5.97 3680.5 - 566349 - - - 2.3857 - 1.522 0.41 - 290.7 1 2 0 0.0033 13 0 0 0 4.24E+06 2.00E+06 - - - 3.1462 1 230117_WJC_METTL3_WT_vs_EV_F04.19408.19408.2 0.0365 18-Nov R.VLALEILPER[166.11].V sp|Q56A73|SPIN4_HUMAN 1 1161.6997 -1 33558 19408 2 1161.702001 581.8571 Spindlin-4 OS=Homo sapiens OX=9606 GN=SPIN4 PE=1 SV=1 4.53 3680.7 - 511589 - - - 1.9979 - 2.38 0.479 - 456.1 1 2 0 0.0023 10 0 0 0 0.00E+00 0.00E+00 - - - 4.9985 0.9186 230117_WJC_METTL3_WT_vs_EV_F04.19410.19410.2 0.0121 16-Aug L.GVLASDLQR.V "sp|O15381|NVL_HUMAN,tr|E9PH71|E9PH71_HUMAN,tr|F8WF01|F8WF01_HUMAN,tr|E7EWK7|E7EWK7_HUMAN,tr|E9PGD8|E9PGD8_HUMAN" 5 957.5243 -1 33560 19410 2 957.525048 479.7694 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 5.84 3681 - 485366 - - - 0.7352 - 1.74 0.232 - 180.6 1 1 0 0.0007 9 0 0 0 0.00E+00 0.00E+00 - - - 2.3568 1 230117_WJC_METTL3_WT_vs_EV_F04.19416.19416.2 0.000334 20-Aug K.VGEVTYVELFK[136.11].D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1290.6951 1.83 33565 19416 2 1290.697087 646.3548 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.53 3681.6 - 1.51E+06 - - - 1.5356 - 2.136 0.482 - 267 1 2 0 0.002 11 0 0 0 3.89E+07 2.13E+07 - - - 4.6535 0.9953 230117_WJC_METTL3_WT_vs_EV_F04.19422.19422.2 0.00215 12-Jul R.EFEFLMR.Q sp|P85037|FOXK1_HUMAN 1 970.4582 2.66 33571 19422 2 970.456914 486.2364 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 4.53 3682.3 - 213466 - - - -1.3653 - 1.383 0.271 - 178.5 1 2 0 -0.0013 7 0 0 0 3.11E+06 1.17E+06 - - - 2.0696 1 230117_WJC_METTL3_WT_vs_EV_F04.19429.19429.2 1.11E-05 13/20 R.LLESLDQLELR.V sp|O95816|BAG2_HUMAN 1 1327.7347 8.74 33576 19429 2 1327.739693 664.8746 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.14 3683.2 - 3.21E+06 - - - 3.7372 - 2.513 0.464 - 588 1 2 0 0.005 11 0 0 0 2.27E+08 2.60E+07 - - - 4.9594 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19434.19434.3 0.00559 Nov-52 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 3.81 33581 19434 3 1541.847565 514.9557 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3683.5 - 781158 - - - 1.4405 - 1.639 0.32 - 116.2 1 2 0 0.0022 14 0 0 0 1.57E+07 4.11E+06 - - - 3.4201 1 230117_WJC_METTL3_WT_vs_EV_F04.19435.19435.2 1.42E-05 15/28 R.VGPDVVTDPAFLVTR.S sp|Q9NV31|IMP3_HUMAN 1 1584.8512 1.36 33582 19435 2 1584.853739 793.4329 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3683.6 - 526939 - - - 1.6285 - 2.625 0.545 - 532.4 1 2 0 0.0026 15 0 0 0 6.68E+06 4.91E+06 - - - 5.4383 1 230117_WJC_METTL3_WT_vs_EV_F04.19436.19436.2 9.04E-05 22-Nov R.LLTWVIGTGSPR[166.11].L sp|Q92616|GCN1_HUMAN 1 1308.7429 1.28 33583 19436 2 1308.745219 655.3787 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.75 3683.7 - 506877 - - - 1.7398 - 2.356 0.524 - 532.9 1 2 0 0.0023 12 0 0 0 5.84E+06 4.57E+06 - - - 5.1654 1 230117_WJC_METTL3_WT_vs_EV_F04.19437.19437.2 1.51E-06 13/28 R.VGPDVVTDPAFLVTR[166.11].S sp|Q9NV31|IMP3_HUMAN 1 1594.8594 1.37 33584 19437 2 1594.86205 798.437 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3683.8 - 451357 - - - 1.644 - 2.181 0.541 - 392.4 1 2 0 0.0026 15 0 0 0 6.74E+06 4.91E+06 - - - 4.9531 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19441.19441.2 0.00412 18-Nov R.AEVVSLLLDR[166.11].K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1123.6476 1.46 33588 19441 2 1123.64854 562.8311 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3684.2 - 262803 - - - 0.7974 - 2.04 0.307 - 621.7 1 2 0 0.0009 10 0 0 0 4.78E+07 3.28E+07 - - - 3.2983 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19443.19443.2 1.04E-05 24-Oct K.LVDSMGWELASVR[166.11].R "sp|O94761|RECQ4_HUMAN,tr|A0A087WTJ0|A0A087WTJ0_HUMAN,tr|A0A087X072|A0A087X072_HUMAN" 3 1471.7369 0.94 33590 19443 2 1471.736692 736.8757 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.37 3684.4 - 200056 - - - -0.1209 - 1.825 0.518 - 260.2 1 2 0 -0.0002 13 0 0 0 1.58E+06 1.68E+06 - - - 4.4109 1 230117_WJC_METTL3_WT_vs_EV_F04.19446.19446.2 3.54E-07 16/26 K.LLDAVDTYIPVPAR[166.11].D sp|P49411|EFTU_HUMAN 1 1551.8536 3.5 33591 19446 2 1551.857153 776.9341 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3684.8 - 8.79E+06 - - - 2.2805 - 3.007 0.592 - 852.7 1 2 0 0.0035 14 0 0 0 1.23E+08 3.52E+07 - - - 6.1752 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19448.19448.2 0.00147 18-Sep R.AEVVSLLLDR.K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1113.6394 1.17 33593 19448 2 1113.643559 557.827 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3684.9 - 3.27E+06 - - - 3.7579 - 2.073 0.441 - 367 1 2 0 0.0042 10 0 0 0 3.85E+07 3.28E+07 - - - 4.3318 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19451.19451.3 4.02E-05 13/52 K.LLDAVDTYIPVPAR[166.11].D sp|P49411|EFTU_HUMAN 1 1551.8536 3.8 33596 19451 3 1551.860474 518.2918 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3685.2 - 1.40E+06 - - - 4.4205 - 2.073 0.392 - 170.2 1 2 0 0.0069 14 0 0 0 1.56E+07 4.11E+06 - - - 4.8458 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.19454.19454.2 0.00304 18-Sep R.LIESLFTIQK[136.11].M "sp|Q12789|TF3C1_HUMAN,tr|H3BU37|H3BU37_HUMAN" 2 1198.7053 1.75 33599 19454 2 1198.710056 600.3599 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 6 3685.5 - 1.12E+06 - - - 3.9885 - 1.817 0.346 - 190.1 1 2 0 0.0048 10 0 0 0 8.23E+06 4.69E+06 - - - 3.262 1 230117_WJC_METTL3_WT_vs_EV_F04.19456.19456.2 2.28E-05 22-Oct R.ELYLEDSPLELK.L sp|Q8TEM1|PO210_HUMAN 1 1447.7446 3.4 33601 19456 2 1447.74736 724.8796 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4 3685.8 - 1.01E+06 - - - 1.8878 - 2.209 0.504 - 274.2 1 2 0 0.0027 12 0 0 0 3.67E+06 1.08E+06 - - - 4.848 1 230117_WJC_METTL3_WT_vs_EV_F04.19457.19457.2 8.80E-05 20-Nov K.IDAELVLPTIR[166.11].S "sp|O95985|TOP3B_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 2 1248.7317 0.87 33602 19457 2 1248.735386 625.3731 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 4.37 3685.9 - 775440 - - - 2.9454 - 2.547 0.504 - 659.9 1 2 0 0.0037 11 0 0 0 3.05E+06 3.50E+06 - - - 5.2916 1 230117_WJC_METTL3_WT_vs_EV_F04.19459.19459.2 3.34E-05 14/26 R.LIVVLEGASLETVK[136.11].V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1477.8847 0.99 33604 19459 2 1477.887825 739.9496 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3686.2 - 702544 - - - 2.1172 - 2.812 0.486 - 607.8 1 2 0 0.0031 14 0 0 0 3.49E+06 3.51E+06 - - - 5.2241 1 230117_WJC_METTL3_WT_vs_EV_F04.19460.19460.2 1.24E-05 13/20 K.IDAELVLPTIR.S "sp|O95985|TOP3B_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 2 1238.7234 0.83 33605 19460 2 1238.730967 620.369 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 4.37 3686.3 - 700961 - - - 6.078 - 2.593 0.427 - 583.9 1 2 0 0.0075 11 0 0 0 2.89E+06 3.50E+06 - - - 4.77 0.9818 230117_WJC_METTL3_WT_vs_EV_F04.19461.19461.2 0.0594 24-Aug R.LSAYVSYGGLLMR[166.11].L "sp|P52434|RPAB3_HUMAN,tr|C9JLU1|C9JLU1_HUMAN" 2 1438.7518 1.39 33606 19461 2 1438.759422 720.3832 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4" 8.59 3686.5 - 576244 - - - 5.3032 - 1.529 0.207 - 125.3 1 2 0 0.0076 13 0 0 0 3.40E+06 2.45E+06 - - - 1.6573 1 230117_WJC_METTL3_WT_vs_EV_F04.19462.19462.2 7.80E-05 15/26 R.LIVVLEGASLETVK.V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1469.8705 0.99 33607 19462 2 1469.872479 735.9425 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3686.6 - 569508 - - - 1.3491 - 3.021 0.513 - 754.6 1 2 0 0.002 14 0 0 0 3.49E+06 3.51E+06 - - - 5.6038 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19468.19468.2 3.92E-05 30-Nov R.MIAGQVLDINLAAEPK.V "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 13 1681.9073 1.69 33612 19468 2 1681.912246 841.9609 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.37 3687.4 - 301135 - - - 2.9449 - 2.031 0.479 - 216.8 1 2 0 0.005 16 0 0 0 1.07E+06 6.30E+05 - - - 4.3193 0.9963 230117_WJC_METTL3_WT_vs_EV_F04.19470.19470.2 0.292 16-Oct K.TFDPYIIIR[166.11].A sp|Q13601|KRR1_HUMAN 1 1146.6313 0.49 33614 19470 2 1146.634688 574.3229 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 5.5 3687.5 - 5.13E+06 - - - 2.9844 - 1.883 0.112 - 357.3 1 2 0 0.0034 9 0 0 0 7.42E+06 1.52E+07 - - - 1.6981 1 230117_WJC_METTL3_WT_vs_EV_F04.19473.19473.2 0.0682 13/20 R.VLITTLITAGR[166.11].L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1166.7262 0.83 33617 19473 2 1166.7283 584.3704 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3687.6 - 3.05E+06 - - - 1.7751 - 2.607 0.458 - 580.9 1 2 0 0.0021 11 0 0 0 9.08E+06 1.09E+07 - - - 5.0153 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19476.19476.2 0.000279 16-Sep K.GLMVLELPK.R "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 998.5834 2.39 33620 19476 2 998.584071 500.299 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6 3687.8 - 2.49E+06 - - - 0.6329 - 1.807 0.397 - 326.8 1 2 0 0.0006 9 0 0 0 5.58E+06 2.34E+06 - - - 3.6848 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19477.19477.2 0.00698 20-Nov R.VLITTLITAGR.L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1156.718 0.83 33621 19477 2 1156.719592 579.3663 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3687.9 - 2.26E+06 - - - 1.4118 - 2.277 0.395 - 399.6 1 2 0 0.0016 11 0 0 0 9.08E+06 1.10E+07 - - - 4.184 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19479.19479.2 0.00356 18-Oct R.EALLAALGYK[136.11].N sp|Q9BU76|MMTA2_HUMAN 1 1055.6106 0.39 33623 19479 2 1055.612401 528.8126 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3688 - 1.80E+06 - - - 1.6616 - 2.344 0.351 - 307.9 1 2 0 0.0018 10 0 0 0 1.64E+07 4.24E+07 - - - 4.0107 0.9972 230117_WJC_METTL3_WT_vs_EV_F04.19481.19481.2 0.0626 20-Nov K.LGLDIEIATYR.R "sp|Q9NSB2|KRT84_HUMAN,sp|Q14533|KRT81_HUMAN,sp|P78386|KRT85_HUMAN,sp|Q9NSB4|KRT82_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|F5GYI5|F5GYI5_HUMAN" 8 1262.6871 12.23 33625 19481 2 1262.68843 632.3508 "Keratin, type II cuticular Hb4 OS=Homo sapiens OX=9606 GN=KRT84 PE=2 SV=2" 4.37 3688.2 - 1.42E+06 - - - 1.0905 - 1.615 0.149 - 277 1 2 0 0.0014 11 0 0 0 1.94E+07 1.59E+06 - - - 1.4378 1 230117_WJC_METTL3_WT_vs_EV_F04.19484.19484.2 5.27E-07 22-Dec K.FATEDEAWAFVR.K sp|O60930|RNH1_HUMAN 1 1440.6674 1.18 33628 19484 2 1440.668028 721.341 Ribonuclease H1 OS=Homo sapiens OX=9606 GN=RNASEH1 PE=1 SV=2 4.14 3688.6 - 974186 - - - 0.4498 - 2.509 0.517 - 466.8 1 2 0 0.0006 12 0 0 0 2.95E+06 2.50E+06 - - - 5.2797 0.9918 230117_WJC_METTL3_WT_vs_EV_F04.19485.19485.2 0.0544 14-Jul K.INFDALLK[136.11].F "sp|P55061|BI1_HUMAN,tr|F8VX73|F8VX73_HUMAN,tr|F8W201|F8W201_HUMAN,tr|F8VSI7|F8VSI7_HUMAN,tr|F8VVJ4|F8VVJ4_HUMAN,tr|F8VPI1|F8VPI1_HUMAN,tr|F8W086|F8W086_HUMAN,tr|F8VQQ5|F8VQQ5_HUMAN,tr|F8VQW0|F8VQW0_HUMAN,tr|F8VR05|F8VR05_HUMAN,tr|F8W1G3|F8W1G3_HUMAN" 11 940.5473 1.4 33629 19485 2 940.548142 471.2809 Bax inhibitor 1 OS=Homo sapiens OX=9606 GN=TMBIM6 PE=1 SV=2 5.84 3688.7 - 916145 - - - 0.8761 - 1.353 0.094 - 78.3 1 2 0 0.0008 8 0 0 0 2.05E+06 1.47E+06 - - - 0.6468 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.19489.19489.2 1.29 12-Jul R.EIFDLIR.S "sp|Q9Y3D0|CIA2B_HUMAN,tr|H3BNV7|H3BNV7_HUMAN,tr|J3KS95|J3KS95_HUMAN" 3 904.5018 2.7 33632 19489 2 904.503116 453.2582 Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1 4.37 3689 - 7.03E+06 - - - 1.435 - 1.512 0.163 - 254.3 1 2 0 0.0013 7 0 0 0 3.74E+07 1.38E+07 - - - 1.5545 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19492.19492.2 0.0697 18-Sep R.EALLAALGYK.N sp|Q9BU76|MMTA2_HUMAN 1 1047.5964 0.43 33635 19492 2 1047.597159 524.8055 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3689.2 - 1.78E+06 - - - 0.6797 - 2.086 0.337 - 209.9 1 2 0 0.0007 10 0 0 0 1.64E+07 3.80E+07 - - - 3.5822 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19495.19495.2 1.73E-05 20-Sep K.VAPGFQFFATR.R sp|Q9NU22|MDN1_HUMAN 1 1239.64 0.69 33638 19495 2 1239.642437 620.8273 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 9.72 3689.5 - 869755 - - - 1.9312 - 1.729 0.467 - 225.4 1 2 0 0.0024 11 0 0 0 4.89E+06 7.06E+06 - - - 3.9707 0.9903 230117_WJC_METTL3_WT_vs_EV_F04.19497.19497.2 0.237 12-Jul R.AFLPLLK.A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 800.516 1.41 33640 19497 2 800.517237 401.2653 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3689.7 - 731797 - - - 1.5315 - 1.317 0.079 - 234.8 1 2 0 0.0012 7 0 0 0 2.39E+07 1.70E+07 - - - 0.4966 1 230117_WJC_METTL3_WT_vs_EV_F04.19505.19505.2 6.56E-05 18-Nov K.LFGYEMAEFK.V sp|Q9UKD2|MRT4_HUMAN 1 1233.574 0.71 33648 19505 2 1233.57725 617.7943 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 4.53 3690.8 - 273482 - - - 2.6371 - 1.781 0.552 - 327.8 1 2 0 0.0033 10 0 0 0 4.49E+06 6.32E+06 - - - 4.7281 1 230117_WJC_METTL3_WT_vs_EV_F04.19507.19507.2 0.000123 13/22 Y.AIYELAVASFPK[136.11].K "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6R9C3|D6R9C3_HUMAN" 4 1315.7267 1.71 33650 19507 2 1315.728946 658.8706 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 6.05 3691 - 177175 - - - 1.6774 - 2.821 0.501 - 604.4 1 1 0 0.0022 12 0 0 0 4.73E+06 2.76E+06 - - - 5.4695 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19511.19511.2 2.02E-05 18-Sep K.LFGYEMAEFK[136.11].V sp|Q9UKD2|MRT4_HUMAN 1 1241.5882 0.71 33653 19511 2 1241.592318 621.8014 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 4.53 3691.5 - 553128 - - - 3.3191 - 1.619 0.485 - 191.4 1 2 0 0.0041 10 0 0 0 4.51E+06 6.32E+06 - - - 3.9668 0.9952 230117_WJC_METTL3_WT_vs_EV_F04.19512.19512.2 0.0676 12-Jul R.FANYIDK.V "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 869.4283 1.08 33654 19512 2 869.431071 435.7214 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.83 3691.6 - 506914 - - - 3.1653 - 1.553 0.154 - 116.4 1 2 0 0.0028 7 0 0 0 2.55E+06 2.36E+06 - - - 1.5723 1 230117_WJC_METTL3_WT_vs_EV_F04.19513.19513.2 3.95E-05 22-Dec K.VIHDNFGIVEGL.M "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1311.6823 - 33655 19513 2 1311.686356 656.8484 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.35 3691.8 - 491044 - - - 3.0907 - 2.713 0.507 - 610.5 1 1 0 0.0041 12 0 0 0 - - - - - 5.4105 0.998 230117_WJC_METTL3_WT_vs_EV_F04.19515.19515.2 0.0268 20-Nov R.LALVISELEGK[136.11].A "sp|Q12899|TRI26_HUMAN,tr|A2AE48|A2AE48_HUMAN" 2 1178.7002 1.48 33657 19515 2 1178.705563 590.3574 Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1 4.53 3692 - 403131 - - - 4.5584 - 2.409 0.301 - 368.7 1 2 0 0.0054 11 0 0 0 4.73E+06 3.20E+06 - - - 3.641 0.999 230117_WJC_METTL3_WT_vs_EV_F04.19518.19518.2 0.0148 14-Oct R.YELALILK[136.11].A sp|P82932|RT06_HUMAN 1 969.599 2.65 33660 19518 2 969.602201 485.8068 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3692.4 - 306775 - - - 3.2818 - 1.751 0.357 - 262.1 1 2 0 0.0032 8 0 0 0 1.87E+07 7.07E+06 - - - 3.3663 1 230117_WJC_METTL3_WT_vs_EV_F04.19520.19520.2 3.54E-08 13/26 K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 2.07 33662 19520 2 1762.79911 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3692.7 - 218390 - - - 2.2748 - 2.412 0.642 - 591.9 1 2 0 0.004 14 0 0 0 5.37E+06 2.59E+06 - - - 5.991 0.9583 230117_WJC_METTL3_WT_vs_EV_F04.19522.19522.2 1.14 24-Jul R.TLGLC[160.03]GTFNGNIR.D "sp|Q3ZCN5|OTOGL_HUMAN,tr|A0A2R8YF04|A0A2R8YF04_HUMAN" 2 1421.7085 35.88 33664 19522 2 1421.712025 711.8615 Otogelin-like protein OS=Homo sapiens OX=9606 GN=OTOGL PE=1 SV=5 7.91 3692.9 - 121000 - - - 2.4562 - 1.25 0.013 - 98.8 1 2 0 0.0035 13 0 0 0 2.25E+06 6.28E+04 - - - -0.2914 0.9877 230117_WJC_METTL3_WT_vs_EV_F04.19535.19535.2 1.37 12-Jun R.AFLPLLK[136.11].A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 808.5302 1.42 33675 19535 2 808.531042 405.2724 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3694.2 - 2.76E+06 - - - 1.0278 - 1.242 0.083 - 192.5 1 2 0 0.0008 7 0 0 0 2.41E+07 1.70E+07 - - - 0.3405 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.19536.19536.2 0.000368 14-Aug R.YELALILK.A sp|P82932|RT06_HUMAN 1 961.5848 2.65 33676 19536 2 961.586317 481.7997 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3694.3 - 2.76E+06 - - - 1.5578 - 1.627 0.14 - 187.2 1 2 0 0.0015 8 0 0 0 1.87E+07 7.07E+06 - - - 1.5425 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19538.19538.2 0.00434 16-Jun R.GWAPVFLDR.E "sp|Q9Y5Y2|NUBP2_HUMAN,tr|H3BQR2|H3BQR2_HUMAN,tr|H3BRE1|H3BRE1_HUMAN,tr|H3BNF0|H3BNF0_HUMAN,tr|H3BNS4|H3BNS4_HUMAN" 5 1059.5502 3.43 33678 19538 2 1059.551975 530.7824 Cytosolic Fe-S cluster assembly factor NUBP2 OS=Homo sapiens OX=9606 GN=NUBP2 PE=1 SV=1 5.84 3694.4 - 2.19E+06 - - - 1.7083 - 1.541 0.386 - 154.1 1 2 0 0.0018 9 0 0 0 1.38E+07 4.03E+06 - - - 3.1425 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19540.19540.2 0.000397 22-Oct R.IEGVLLLGEPVR.W "sp|Q9BXW7|HDHD5_HUMAN,tr|A8MYZ9|A8MYZ9_HUMAN" 2 1293.7656 2.89 33680 19540 2 1293.765102 647.8901 Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Homo sapiens OX=9606 GN=HDHD5 PE=1 SV=1 4.53 3694.5 - 968843 - - - -0.4135 - 2.354 0.408 - 468.3 1 2 0 -0.0005 12 0 0 0 6.10E+06 2.11E+06 - - - 4.3069 1 230117_WJC_METTL3_WT_vs_EV_F04.19541.19541.2 0.00973 13/22 Y.AIYELAVASFPK.K "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6R9C3|D6R9C3_HUMAN" 4 1307.7125 1.71 33681 19541 2 1307.715228 654.8635 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 6.05 3694.6 - 958910 - - - 2.0563 - 2.731 0.45 - 659.2 1 1 0 0.0027 12 0 0 0 4.73E+06 2.76E+06 - - - 5.0073 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.19543.19543.2 0.0142 12-May R.EAYFWLR[166.11].Q sp|Q8TCJ2|STT3B_HUMAN 1 993.4948 1.17 33683 19543 2 993.495649 497.7547 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1 6.1 3694.8 - 804456 - - - 0.8827 - 1.243 0.389 - 118.6 1 2 0 0.0009 7 0 0 0 5.11E+06 4.36E+06 - - - 2.6031 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19544.19544.2 9.28E-05 16-Oct R.GWAPVFLDR[166.11].E "sp|Q9Y5Y2|NUBP2_HUMAN,tr|H3BQR2|H3BQR2_HUMAN,tr|H3BRE1|H3BRE1_HUMAN,tr|H3BNF0|H3BNF0_HUMAN,tr|H3BNS4|H3BNS4_HUMAN" 5 1069.5584 3.55 33684 19544 2 1069.56191 535.7865 Cytosolic Fe-S cluster assembly factor NUBP2 OS=Homo sapiens OX=9606 GN=NUBP2 PE=1 SV=1 5.84 3694.9 - 780686 - - - 3.249 - 1.817 0.433 - 274.8 1 2 0 0.0035 9 0 0 0 1.36E+07 3.82E+06 - - - 3.9657 1 230117_WJC_METTL3_WT_vs_EV_F04.19546.19546.2 1.00E-06 13/26 K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 2.07 33686 19546 2 1772.807379 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3695.1 - 642411 - - - 2.2614 - 2.578 0.667 - 599 1 2 0 0.004 14 0 0 0 5.37E+06 2.59E+06 - - - 6.3427 0.983 230117_WJC_METTL3_WT_vs_EV_F04.19551.19551.2 0.00347 18-Dec R.IINDLLQSLR.S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1183.6925 2.18 33689 19551 2 1183.700155 592.8535 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3695.7 - 2.17E+07 - - - 6.4907 - 2.334 0.147 - 476.6 1 2 0 0.0077 10 0 0 0 1.43E+08 6.53E+07 - - - 2.4902 0.9749 230117_WJC_METTL3_WT_vs_EV_F04.19552.19552.2 0.0067 18-Jul R.IINDLLQSLR[166.11].S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1193.7007 2.18 33690 19552 2 1193.707444 597.8576 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3695.7 - 1.04E+07 - - - 5.6145 - 1.847 0.109 - 109.4 1 2 0 0.0067 10 0 0 0 1.43E+08 6.53E+07 - - - 1.5566 1 230117_WJC_METTL3_WT_vs_EV_F04.19553.19553.2 0.000154 18-Oct R.LGLEDFESLK[136.11].V sp|Q15208|STK38_HUMAN 1 1157.606 0.55 33691 19553 2 1157.608447 579.8103 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3695.8 - 2.85E+06 - - - 2.1527 - 2.168 0.527 - 253 1 2 0 0.0025 10 0 0 0 3.52E+08 6.39E+08 - - - 5.0926 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19560.19560.2 0.0807 12-Jun R.EAYFWLR.Q sp|Q8TCJ2|STT3B_HUMAN 1 983.4865 1.1 33698 19560 2 983.48773 492.7505 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1 6.1 3696.3 - 679952 - - - 1.2486 - 1.263 0.381 - 178.5 1 2 0 0.0012 7 0 0 0 5.18E+06 4.71E+06 - - - 2.5945 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19561.19561.2 0.00203 20-Nov K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 7.12 33699 19561 2 1276.706829 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3696.4 - 591636 - - - 3.2318 - 2.454 0.376 - 559.3 1 2 0 0.0041 11 0 0 0 4.98E+06 6.99E+05 - - - 4.2454 1 230117_WJC_METTL3_WT_vs_EV_F04.19569.19569.2 0.0063 18-Oct R.LGLEDFESLK.V sp|Q15208|STK38_HUMAN 1 1149.5918 0.55 33705 19569 2 1149.597007 575.8032 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3697.4 - 6.28E+06 - - - 4.5686 - 2.252 0.46 - 231.5 1 2 0 0.0053 10 0 0 0 3.52E+08 6.39E+08 - - - 4.7029 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19572.19572.2 0.00693 18-Nov R.TALYNYIFAK.K "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1202.6336 2.99 33708 19572 2 1202.635836 602.3241 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 8.17 3697.8 - 1.17E+06 - - - 1.8925 - 2.128 0.346 - 362.1 1 2 0 0.0023 10 0 0 0 6.90E+06 2.31E+06 - - - 3.7038 0.9389 230117_WJC_METTL3_WT_vs_EV_F04.19573.19573.2 0.391 16-Aug K.LQLSLADFR[166.11].R "sp|O00541|PESC_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 2 1071.5952 0.94 33709 19573 2 1071.603899 536.8049 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 5.84 3697.9 - 1.15E+06 - - - 8.1038 - 1.672 0.2 - 178.1 1 2 0 0.0087 9 0 0 0 2.49E+07 2.66E+07 - - - 2.0026 1 230117_WJC_METTL3_WT_vs_EV_F04.19576.19576.2 3.68E-05 22-Oct R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.13 33712 19576 2 1323.804219 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3698.3 - 364756 - - - 2.7542 - 2.013 0.515 - 252.9 1 2 0 0.0036 12 0 0 0 2.68E+06 2.37E+06 - - - 4.6845 1 230117_WJC_METTL3_WT_vs_EV_F04.19582.19582.2 3.89E-07 14/32 R.IQEIIEQLDVTTSEYEK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2037.0154 2.34 33718 19582 2 2037.020987 1019.515 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3699.1 - 160521 - - - 2.7516 - 3.274 0.602 - 474.8 1 2 0 0.0056 17 0 0 0 2.51E+06 1.07E+06 - - - 6.4015 0.9705 230117_WJC_METTL3_WT_vs_EV_F04.19588.19588.2 0.517 16-Aug K.GLFEVNPWK.R "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1088.5655 3.39 33722 19588 2 1088.564279 545.29 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 6 3699.8 - 2.50E+06 - - - -1.1042 - 1.522 0.044 - 157 2 2 0 -0.0012 9 0 0 0 4.46E+07 1.32E+07 - - - 0.4463 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19589.19589.2 0.0045 16-Sep K.GLFEVNPWK[136.11].R "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1096.5797 3.18 33723 19589 2 1096.580606 549.2971 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 6 3699.9 - 1.25E+06 - - - 0.8435 - 1.699 0.363 - 255.1 1 2 0 0.0009 9 0 0 0 4.15E+07 1.30E+07 - - - 3.2553 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.19592.19592.2 0.0554 14-Jun R.LLFFAPTR.R sp|Q07820|MCL1_HUMAN 1 963.5542 4.48 33726 19592 2 963.555143 482.7844 Induced myeloid leukemia cell differentiation protein Mcl-1 OS=Homo sapiens OX=9606 GN=MCL1 PE=1 SV=3 9.75 3700.1 - 987062 - - - 0.9911 - 1.413 0.196 - 136.7 1 2 0 0.001 8 0 0 0 9.62E+06 2.15E+06 - - - 1.531 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19593.19593.2 0.23 14-Oct K.VAIIIPFR.N "sp|P15291|B4GT1_HUMAN,sp|O43286|B4GT5_HUMAN,tr|Q86XA6|Q86XA6_HUMAN" 3 927.5906 0.22 33727 19593 2 927.592029 464.8026 "Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5" 9.72 3700.3 - 908788 - - - 1.5697 - 1.991 0.222 - 399.5 1 2 0 0.0015 8 0 0 0 1.14E+07 5.12E+07 - - - 2.7571 0.9843 230117_WJC_METTL3_WT_vs_EV_F04.19594.19594.2 0.00342 18-Nov R.TEVVSLLLDR.K "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1143.6499 2.16 33728 19594 2 1143.656969 572.8322 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 3700.3 - 851885 - - - 6.147 - 2.004 0.184 - 400.1 1 2 0 0.007 10 0 0 0 2.55E+07 1.18E+07 - - - 2.3382 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19595.19595.2 0.0238 14-Sep K.VAIIIPFR[166.11].N "sp|P15291|B4GT1_HUMAN,sp|O43286|B4GT5_HUMAN,tr|Q86XA6|Q86XA6_HUMAN" 3 937.5988 0.96 33729 19595 2 937.600381 469.8067 "Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5" 9.72 3700.5 - 848973 - - - 1.6404 - 1.943 0.226 - 325.8 1 2 0 0.0015 8 0 0 0 9.58E+06 1.00E+07 - - - 2.713 0.9845 230117_WJC_METTL3_WT_vs_EV_F04.19596.19596.2 0.00207 14-Jul R.NYFGLFPR[166.11].V sp|Q8WUF5|IASPP_HUMAN 1 1022.5213 1.62 33730 19596 2 1022.518032 512.2679 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.75 3700.6 - 761038 - - - -3.2166 - 1.328 0.289 - 141.7 1 2 0 -0.0033 8 0 0 0 1.43E+07 8.79E+06 - - - 2.0301 1 230117_WJC_METTL3_WT_vs_EV_F04.19597.19597.2 1.41E-06 26-Dec R.IMGIPEEEQMGLLR[166.11].V sp|P35579|MYH9_HUMAN 1 1624.8192 2.24 33731 19597 2 1624.825767 813.4169 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3700.7 - 410990 - - - 4.03 - 2.318 0.615 - 331.8 1 2 0 0.0065 14 0 0 0 1.17E+07 5.25E+06 - - - 5.691 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.19600.19600.2 9.98E-07 13/24 R.LENLGIPEEELLR.Q sp|Q01658|NC2B_HUMAN 1 1523.8195 2.31 33734 19600 2 1523.826602 762.917 Protein Dr1 OS=Homo sapiens OX=9606 GN=DR1 PE=1 SV=1 4.09 3701 - 244461 - - - 4.6456 - 2.941 0.368 - 439.3 1 2 0 0.0071 13 0 0 0 4.97E+06 2.15E+06 - - - 4.5255 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19607.19607.2 0.0753 16-Jul K.LQLSLADFR.R "sp|O00541|PESC_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 2 1061.5869 0.94 33739 19607 2 1061.588892 531.8007 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 5.84 3701.9 - 1.24E+07 - - - 1.834 - 1.568 0.318 - 178.2 1 2 0 0.0019 9 0 0 0 2.49E+07 2.66E+07 - - - 2.6904 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.19608.19608.2 0.0497 16-Sep K.ALEVYDLIR.T "sp|Q9H5X1|CIA2A_HUMAN,tr|H0YKV4|H0YKV4_HUMAN" 2 1090.6023 1.53 33740 19608 2 1090.606002 546.3084 Cytosolic iron-sulfur assembly component 2A OS=Homo sapiens OX=9606 GN=CIAO2A PE=1 SV=1 4.37 3701.9 - 5.42E+06 - - - 3.4311 - 1.792 0.305 - 253.7 1 2 0 0.0037 9 0 0 0 1.55E+07 1.01E+07 - - - 2.9802 0.919 230117_WJC_METTL3_WT_vs_EV_F04.19611.19611.2 0.306 14-Sep L.IALALLAR.R sp|P43116|PE2R2_HUMAN 1 839.5593 999 33743 19611 2 839.55979 420.7869 Prostaglandin E2 receptor EP2 subtype OS=Homo sapiens OX=9606 GN=PTGER2 PE=1 SV=2 9.75 3702.1 - 4.31E+06 - - - 0.6158 - 1.947 0.183 - 365.4 1 1 0 0.0005 8 0 0 0 9.87E+06 0.00E+00 - - - 2.402 1 230117_WJC_METTL3_WT_vs_EV_F04.19614.19614.2 3.02E-06 22-Oct R.LPADTC[160.03]LLEFAR.L "sp|Q8NF37|PCAT1_HUMAN,tr|A0A0G2JQ62|A0A0G2JQ62_HUMAN,tr|A0A0G2JRI7|A0A0G2JRI7_HUMAN" 3 1404.7071 1.72 33746 19614 2 1404.709121 703.3608 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 4.37 3702.3 - 3.53E+06 - - - 1.4131 - 2.006 0.541 - 348 1 2 0 0.002 12 0 0 0 1.03E+07 5.96E+06 - - - 4.8679 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.19615.19615.2 0.688 12-Jul K.LTFLDLR.N "sp|Q9H9A6|LRC40_HUMAN,tr|X6R5P2|X6R5P2_HUMAN" 2 876.5069 1.5 33747 19615 2 876.507571 439.2607 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.84 3702.3 - 3.53E+06 - - - 0.7621 - 1.548 0.159 - 240.4 1 2 0 0.0007 7 0 0 0 9.34E+06 6.22E+06 - - - 1.5997 0.9293 230117_WJC_METTL3_WT_vs_EV_F04.19617.19617.2 6.48 12-Jun R.QVLQLLS.- "sp|Q9BRJ6|CG050_HUMAN,tr|H7C2R9|H7C2R9_HUMAN,tr|H7C0T1|H7C0T1_HUMAN" 3 799.4804 - 33749 19617 2 799.481171 400.7475 Uncharacterized protein C7orf50 OS=Homo sapiens OX=9606 GN=C7orf50 PE=1 SV=1 5.52 3702.5 - 2.82E+06 - - - 1.0219 - 1.015 0.014 - 86.3 1 2 0 0.0008 7 0 0 0 - - - - - -0.8087 0.999 230117_WJC_METTL3_WT_vs_EV_F04.19618.19618.2 0.0717 12-Aug K.NFGIWLR[166.11].Y "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 914.5002 0.81 33750 19618 2 914.501855 458.2574 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 9.75 3702.5 - 2.81E+06 - - - 1.8185 - 1.684 0.241 - 374.8 1 2 0 0.0017 7 0 0 0 1.21E+08 1.49E+08 - - - 2.4719 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.19620.19620.2 1.07 12-Jul K.LTFLDLR[166.11].N "sp|Q9H9A6|LRC40_HUMAN,tr|X6R5P2|X6R5P2_HUMAN" 2 886.5152 1.5 33752 19620 2 886.516552 444.2649 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.84 3702.6 - 2.71E+06 - - - 1.5555 - 1.56 0.159 - 226.2 1 2 0 0.0014 7 0 0 0 9.36E+06 6.26E+06 - - - 1.624 0.9965 230117_WJC_METTL3_WT_vs_EV_F04.19621.19621.2 3.12 14-Jun K.SLLAGLLK[136.11].K "sp|P31751|AKT2_HUMAN,tr|M0R0P9|M0R0P9_HUMAN,tr|J3QKW1|J3QKW1_HUMAN,tr|J3QL45|J3QL45_HUMAN,tr|M0R283|M0R283_HUMAN,tr|M0QZW8|M0QZW8_HUMAN" 6 821.5466 0.68 33753 19621 2 821.547455 411.7806 RAC-beta serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=AKT2 PE=1 SV=2 8.47 3702.7 - 1.59E+06 - - - 1.0529 - 1.312 0.189 - 108 1 2 0 0.0009 8 0 0 0 1.98E+06 2.93E+06 - - - 1.2557 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.19622.19622.2 0.14 20-Aug K.NLIEMSELEIK.H sp|Q9Y5X3|SNX5_HUMAN 1 1317.685 9.58 33754 19622 2 1317.689022 659.8498 Sorting nexin-5 OS=Homo sapiens OX=9606 GN=SNX5 PE=1 SV=1 4.25 3702.8 - 1.43E+06 - - - 3.0493 - 1.655 0.326 - 186.9 1 2 0 0.004 11 0 0 0 4.24E+06 4.43E+05 - - - 2.8105 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19623.19623.2 0.00246 24-Nov K.ALLLVPASVNC[160.03]LR.L sp|Q5SRE5|NU188_HUMAN 1 1424.8174 0.67 33755 19623 2 1424.819364 713.416 Nucleoporin NUP188 OS=Homo sapiens OX=9606 GN=NUP188 PE=1 SV=1 8.29 3702.9 - 1.22E+06 - - - 1.4093 - 2.069 0.328 - 324.6 1 2 0 0.002 13 0 0 0 3.28E+06 4.93E+06 - - - 3.329 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.19626.19626.2 0.0508 16-Jun R.VLLPVLLNK[136.11].N sp|O00186|STXB3_HUMAN 1 1015.6885 1.78 33757 19626 2 1015.691298 508.8515 Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2 8.72 3703.3 - 331074 - - - 2.7518 - 1.255 0.296 - 64.5 1 2 0 0.0028 9 0 0 0 9.41E+06 5.29E+06 - - - 1.8835 1 230117_WJC_METTL3_WT_vs_EV_F04.19630.19630.2 6.10E-08 26-Nov R.IMGIPEEEQMGLLR.V sp|P35579|MYH9_HUMAN 1 1614.8109 2.18 33761 19630 2 1614.812663 808.4128 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3703.7 - 698461 - - - 1.0614 - 2.16 0.657 - 305.3 1 2 0 0.0017 14 0 0 0 1.21E+07 5.54E+06 - - - 5.8256 1 230117_WJC_METTL3_WT_vs_EV_F04.19631.19631.2 0.000237 20-Dec R.LFEAEAQDLFR.D sp|Q9H223|EHD4_HUMAN 1 1337.6616 2.34 33762 19631 2 1337.66372 669.8381 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3703.8 - 486342 - - - 1.6103 - 2.582 0.47 - 521.8 1 2 0 0.0022 11 0 0 0 3.26E+07 1.39E+07 - - - 5.0778 1 230117_WJC_METTL3_WT_vs_EV_F04.19633.19633.2 5.07E-07 14/28 R.VMAGALEGDIFIGPK.A "sp|P61163|ACTZ_HUMAN,sp|P42025|ACTY_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 4 1516.796 1.46 33764 19633 2 1516.798244 759.4053 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4.37 3704.1 - 318266 - - - 1.5117 - 2.76 0.574 - 553.2 1 2 0 0.0023 15 0 0 0 1.66E+07 1.14E+07 - - - 5.7758 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.19635.19635.2 0.0105 22-Sep R.LLSAGQLLFQGR[166.11].A sp|Q567V2|M17L2_HUMAN 1 1311.7538 0.78 33766 19635 2 1311.751554 656.8842 Mpv17-like protein 2 OS=Homo sapiens OX=9606 GN=MPV17L2 PE=1 SV=2 9.75 3704.3 - 263371 - - - -1.7435 - 1.863 0.277 - 139.7 1 2 0 -0.0023 12 0 0 0 1.31E+06 1.68E+06 - - - 2.7233 1 230117_WJC_METTL3_WT_vs_EV_F04.19637.19637.2 0.076 20-Dec R.LFEAEAQDLFR[166.11].D sp|Q9H223|EHD4_HUMAN 1 1347.6698 2.34 33768 19637 2 1347.670394 674.8422 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3704.6 - 248785 - - - 0.414 - 2.48 0.468 - 522.7 1 2 0 0.0006 11 0 0 0 3.26E+07 1.39E+07 - - - 4.9545 0.9765 230117_WJC_METTL3_WT_vs_EV_F04.19638.19638.2 0.0972 14-Aug K.SVWALLQR[166.11].N sp|Q5VUD6|DIK1B_HUMAN 1 981.5635 2 33769 19638 2 981.568986 491.789 Divergent protein kinase domain 1B OS=Homo sapiens OX=9606 GN=DIPK1B PE=1 SV=3 9.47 3704.7 - 198238 - - - 5.5687 - 1.449 0.194 - 198.5 1 2 0 0.0055 8 0 0 0 4.81E+06 2.40E+06 - - - 1.5907 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.19642.19642.2 0.114 18-Oct K.ELVLLLDEER.A sp|A6NKD9|CC85C_HUMAN 1 1227.6711 56.14 33771 19642 2 1227.675561 614.8428 Coiled-coil domain-containing protein 85C OS=Homo sapiens OX=9606 GN=CCDC85C PE=1 SV=1 4 3705.2 - 348772 - - - 3.6598 - 2.192 0.289 - 302.3 1 2 0 0.0045 10 0 0 0 1.84E+07 3.28E+05 - - - 3.3648 1 230117_WJC_METTL3_WT_vs_EV_F04.19643.19643.2 0.00119 14/22 R.LPADTC[160.03]LLEFAR[166.11].L "sp|Q8NF37|PCAT1_HUMAN,tr|A0A0G2JQ62|A0A0G2JQ62_HUMAN,tr|A0A0G2JRI7|A0A0G2JRI7_HUMAN" 3 1414.7154 1.7 33772 19643 2 1414.718659 708.365 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 4.37 3705.3 - 231287 - - - 2.2994 - 2.68 0.467 - 1002.6 1 2 0 0.0033 12 0 0 0 1.03E+07 6.04E+06 - - - 5.0831 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19646.19646.2 0.000138 24-Oct K.IYVDDGLISLQVK.Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1461.8079 1.43 33775 19646 2 1461.811082 731.9112 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3705.7 - 322580 - - - 2.1795 - 1.996 0.444 - 219.6 1 2 0 0.0032 13 0 0 0 9.88E+06 6.91E+06 - - - 4.0932 1 230117_WJC_METTL3_WT_vs_EV_F04.19647.19647.2 1.43E-05 24-Nov K.IYVDDGLISLQVK[136.11].Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1469.8221 1.46 33776 19647 2 1469.826216 735.9183 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3705.8 - 298051 - - - 2.8031 - 2.188 0.494 - 284.7 1 2 0 0.0041 13 0 0 0 9.88E+06 6.75E+06 - - - 4.698 1 230117_WJC_METTL3_WT_vs_EV_F04.19649.19649.2 4.00E-08 13/24 K.LLC[160.03]DSVVLQPYLR.E "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN,tr|H0YBB4|H0YBB4_HUMAN" 3 1574.8491 3.37 33778 19649 2 1574.852282 788.4318 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.83 3706.1 - 243985 - - - 2.0523 - 2.6 0.471 - 653.6 1 2 0 0.0032 13 0 0 0 5.53E+06 1.64E+06 - - - 4.9711 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19650.19650.2 2.07E-06 13/22 K.YGLEGTVFFEEK[136.11].D "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1425.6907 2.9 33779 19650 2 1425.695919 713.8527 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.25 3706.2 - 188431 - - - 3.627 - 1.866 0.508 - 379.6 1 2 0 0.0052 12 0 0 0 7.72E+06 2.66E+06 - - - 4.4328 0.9923 230117_WJC_METTL3_WT_vs_EV_F04.19651.19651.2 3.84E-05 24-Oct R.LGIGMDTC[160.03]VIPLR.H "sp|P49903|SPS1_HUMAN,tr|Q5T5U6|Q5T5U6_HUMAN" 2 1443.7578 5.46 33780 19651 2 1443.768002 722.8862 "Selenide, water dikinase 1 OS=Homo sapiens OX=9606 GN=SEPHS1 PE=1 SV=2" 5.83 3706.4 - 106660 - - - 7.0718 - 2.005 0.463 - 276.4 1 2 0 0.0102 13 0 0 0 1.75E+06 3.21E+05 - - - 4.2429 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19654.19654.2 0.00272 18-Aug K.VAEITELILK[136.11].A "sp|Q06265|EXOS9_HUMAN,tr|D6R905|D6R905_HUMAN,tr|H0Y9L5|H0Y9L5_HUMAN,tr|D6RIY6|D6RIY6_HUMAN" 4 1135.6944 1.15 33782 19654 2 1135.697907 568.8545 Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3 4.53 3706.9 - 590651 - - - 3.1091 - 2.004 0.356 - 176 1 2 0 0.0035 10 0 0 0 3.68E+07 3.21E+07 - - - 3.6097 0.998 230117_WJC_METTL3_WT_vs_EV_F04.19660.19660.2 0.022 16-Aug K.LFSNVLILK.S "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1045.6536 1.49 33788 19660 2 1045.657024 523.8341 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.75 3707.6 - 502353 - - - 3.3051 - 1.373 0.344 - 128.9 1 2 0 0.0035 9 0 0 0 1.02E+07 6.84E+06 - - - 2.4978 1 230117_WJC_METTL3_WT_vs_EV_F04.19663.19663.2 9.31E-05 18-Dec K.LLDEVFFSEK.L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1225.6231 1.6 33791 19663 2 1225.626588 613.8188 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3708 - 351526 - - - 2.8826 - 2.406 0.426 - 393.4 1 2 0 0.0035 10 0 0 0 1.98E+08 1.24E+08 - - - 4.637 0.9471 230117_WJC_METTL3_WT_vs_EV_F04.19665.19665.2 1.42 18-Jun R.FPPVVFYTPK.E "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1193.6485 2.9 33793 19665 2 1193.653781 597.8315 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3708.3 - 255808 - - - 4.4393 - 1.185 0.116 - 71.6 1 2 0 0.0053 10 0 0 0 2.08E+06 7.19E+05 - - - 0.3699 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19666.19666.2 0.000239 22-Oct K.ALSTFFVENSLR[166.11].T sp|Q9Y2V7|COG6_HUMAN 1 1392.7277 2.02 33794 19666 2 1392.729065 697.3711 Conserved oligomeric Golgi complex subunit 6 OS=Homo sapiens OX=9606 GN=COG6 PE=1 SV=2 6.05 3708.4 - 196960 - - - 0.9909 - 1.989 0.361 - 403 1 2 0 0.0014 12 0 0 0 6.82E+06 3.38E+06 - - - 3.5162 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.19669.19669.2 0.00976 14-Sep R.NLFEQLVR.R "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VV47|F8VV47_HUMAN,tr|F8VUW9|F8VUW9_HUMAN,tr|F8VWY4|F8VWY4_HUMAN,tr|F8VRD2|F8VRD2_HUMAN,tr|F8VVY0|F8VVY0_HUMAN,tr|F8VZ66|F8VZ66_HUMAN,tr|F8VWX0|F8VWX0_HUMAN,tr|F8VS54|F8VS54_HUMAN,tr|F8W0L1|F8W0L1_HUMAN,tr|F8VVE5|F8VVE5_HUMAN,tr|F8VV39|F8VV39_HUMAN,tr|F8VXH1|F8VXH1_HUMAN" 13 1017.5607 2.74 33796 19669 2 1017.564053 509.7876 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 6 3708.7 - 875338 - - - 3.2657 - 1.53 0.266 - 324.2 1 2 0 0.0033 8 0 0 0 1.63E+07 5.94E+06 - - - 2.2872 0.9827 230117_WJC_METTL3_WT_vs_EV_F04.19670.19670.2 2.09 18-Jul K.VAEITELILK.A "sp|Q06265|EXOS9_HUMAN,tr|D6R905|D6R905_HUMAN,tr|H0Y9L5|H0Y9L5_HUMAN,tr|D6RIY6|D6RIY6_HUMAN" 4 1127.6802 1.15 33797 19670 2 1127.682941 564.8474 Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3 4.53 3708.8 - 134935 - - - 2.4519 - 1.065 0.146 - 92 1 2 0 0.0028 10 0 0 0 3.68E+07 3.21E+07 - - - 0.2943 0.998 230117_WJC_METTL3_WT_vs_EV_F04.19671.19671.2 1.1 14-Aug K.LLILALER[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 949.62 1.29 33798 19671 2 949.621968 475.8173 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6 3708.9 - 1.26E+06 - - - 2.1008 - 1.716 0.157 - 223.7 1 2 0 0.002 8 0 0 0 4.83E+07 3.73E+07 - - - 1.8286 1 230117_WJC_METTL3_WT_vs_EV_F04.19672.19672.2 0.00023 18-Dec K.LLDEVFFSEK[136.11].L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1233.6373 1.6 33799 19672 2 1233.640095 617.8259 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3709 - 960108 - - - 2.3021 - 2.384 0.487 - 405.7 1 2 0 0.0028 10 0 0 0 1.98E+08 1.24E+08 - - - 5.0621 1 230117_WJC_METTL3_WT_vs_EV_F04.19673.19673.2 3.20E-07 18-Dec R.C[160.03]LFQSPLFAK.A sp|Q86X55|CARM1_HUMAN 1 1209.6216 2.2 33800 19673 2 1209.623652 605.8181 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 8.22 3709.1 - 543419 - - - 1.6832 - 1.948 0.544 - 408.8 1 2 0 0.002 10 0 0 0 8.92E+06 4.05E+06 - - - 4.9196 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.19675.19675.2 0.0511 16-Aug R.VLLPVLLNK.N sp|O00186|STXB3_HUMAN 1 1007.6743 1.78 33802 19675 2 1007.676109 504.8444 Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2 8.72 3709.3 - 351273 - - - 1.7922 - 1.639 0.243 - 147.7 1 2 0 0.0018 9 0 0 0 9.41E+06 5.29E+06 - - - 2.2646 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.19677.19677.3 7.15E-06 21/68 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 2.48 33804 19677 3 1918.068896 640.3618 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3709.6 - 276553 - - - 2.7559 - 2.906 0.508 - 318.8 1 2 0 0.0053 18 0 0 0 3.59E+07 1.45E+07 - - - 6.8586 0.987 230117_WJC_METTL3_WT_vs_EV_F04.19678.19678.2 4.73E-05 22-Dec R.IYGLGSLALYEK.A sp|P36542|ATPG_HUMAN 1 1325.7231 1.55 33805 19678 2 1325.734421 663.8688 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6 3709.7 - 93853.2 - - - 8.5365 - 2.461 0.419 - 398.7 1 2 0 0.0113 12 0 0 0 3.52E+08 2.27E+08 - - - 4.5017 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19683.19683.2 0.0103 16-Jul K.VIPTLALLK.D sp|O14530|TXND9_HUMAN 1 966.6478 2.04 33808 19683 2 966.649268 484.3312 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 8.72 3710.2 - 1.97E+06 - - - 1.5662 - 1.454 0.332 - 123.2 1 2 0 0.0015 9 0 0 0 1.50E+07 7.35E+06 - - - 2.5756 0.9674 230117_WJC_METTL3_WT_vs_EV_F04.19684.19684.2 0.00251 14-Aug F.GPILNFLR.H "sp|Q8N5Z5|KCD17_HUMAN,tr|H7C323|H7C323_HUMAN,tr|B0QYB2|B0QYB2_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 5 928.5494 0.57 33809 19684 2 928.551141 465.282 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 9.75 3710.3 - 1.09E+06 - - - 1.8351 - 1.918 0.347 - 318.7 1 1 0 0.0017 8 0 0 0 1.36E+07 2.39E+07 - - - 3.5676 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.19685.19685.2 0.111 16-Aug K.LFSNVLILK[136.11].S "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1053.6678 1.55 33810 19685 2 1053.670202 527.8412 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.75 3710.4 - 953541 - - - 2.31 - 1.381 0.306 - 129.5 1 2 0 0.0024 9 0 0 0 1.02E+07 6.58E+06 - - - 2.2343 0.9967 230117_WJC_METTL3_WT_vs_EV_F04.19686.19686.2 0.0613 16-Jul K.VIPTLALLK[136.11].D sp|O14530|TXND9_HUMAN 1 974.662 2.04 33811 19686 2 974.664707 488.3383 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 8.72 3710.6 - 906461 - - - 2.8246 - 1.005 0.362 - 78.5 1 2 0 0.0028 9 0 0 0 1.50E+07 7.35E+06 - - - 1.7283 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.19687.19687.3 4.15E-06 18/68 K.ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1928.0719 2.54 33812 19687 3 1928.075178 643.6979 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3710.7 - 872986 - - - 1.7105 - 2.874 0.432 - 154 1 2 0 0.0033 18 0 0 0 3.68E+07 1.45E+07 - - - 5.9843 1 230117_WJC_METTL3_WT_vs_EV_F04.19688.19688.2 8.61E-06 13/20 R.EVWALVQAGIR.D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1240.6928 1.45 33813 19688 2 1240.697547 621.3537 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.1 3710.8 - 637974 - - - 3.8204 - 2.015 0.511 - 458.9 1 2 0 0.0047 11 0 0 0 1.30E+07 8.97E+06 - - - 4.7091 0.9317 230117_WJC_METTL3_WT_vs_EV_F04.19690.19690.2 5.55 16-Jun R.FELLTNFPR.R "sp|O94888|UBXN7_HUMAN,tr|C9JAT7|C9JAT7_HUMAN" 2 1135.6026 7.05 33815 19690 2 1135.603882 568.8086 UBX domain-containing protein 7 OS=Homo sapiens OX=9606 GN=UBXN7 PE=1 SV=2 6 3711.1 - 519348 - - - 1.1333 - 1.155 0.008 - 58 5 2 0 0.0013 9 0 0 0 3.87E+06 5.49E+05 - - - -0.7957 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19691.19691.2 0.0129 20-Oct K.TAAFALPVLER.L "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 1186.671 1.15 33816 19691 2 1186.672232 594.3428 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.66 3711.2 - 517104 - - - 1.0306 - 2.014 0.39 - 384.2 1 2 0 0.0012 11 0 0 0 9.48E+06 8.22E+06 - - - 3.8152 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.19694.19694.3 3.24E-07 15/76 R.LALVTGGEIASTFDHPELVK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2096.1154 999 33819 19694 3 2096.123892 699.7124 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 3711.6 - 492026 - - - 4.0651 - 2.931 0.511 - 206.5 1 2 0 0.0085 20 0 0 0 6.38E+06 0.00E+00 - - - 6.8436 1 230117_WJC_METTL3_WT_vs_EV_F04.19700.19700.2 1.82E-06 13/22 R.IYGLGSLALYEK[136.11].A sp|P36542|ATPG_HUMAN 1 1333.7373 1.55 33824 19700 2 1333.739961 667.8759 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6 3712.3 - 4.38E+06 - - - 1.9921 - 2.613 0.51 - 478.7 1 2 0 0.0027 12 0 0 0 3.52E+08 2.27E+08 - - - 5.3343 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.19702.19702.2 0.0128 16-Nov K.TLFPLIEAK[136.11].K sp|P13010|XRCC5_HUMAN 1 1038.6205 1.06 33826 19702 2 1038.62461 520.3175 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.66 3712.6 - 1.33E+06 - - - 3.9735 - 1.647 0.368 - 328.3 1 2 0 0.0041 9 0 0 0 3.22E+08 3.04E+08 - - - 3.2013 0.9968 230117_WJC_METTL3_WT_vs_EV_F04.19704.19704.2 0.00077 14-Aug R.YILATLLK.E "sp|Q6PI48|SYDM_HUMAN,tr|A0A3B3IS01|A0A3B3IS01_HUMAN,tr|A0A3B3ISK7|A0A3B3ISK7_HUMAN,tr|A0A3B3IT01|A0A3B3IT01_HUMAN" 4 933.5899 0.86 33828 19704 2 933.592629 467.8022 "Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2 PE=1 SV=1" 8.59 3712.8 - 1.04E+06 - - - 2.9178 - 1.429 0.228 - 148.9 1 2 0 0.0027 8 0 0 0 6.41E+06 7.45E+06 - - - 1.8008 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.19705.19705.2 9.01E-05 13/24 R.GLLPGLLPAPADK[136.11].L sp|Q6P2E9|EDC4_HUMAN 1 1268.7584 1.91 33829 19705 2 1268.760698 635.3865 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 5.84 3712.9 - 665858 - - - 1.8317 - 2.343 0.186 - 515.3 1 2 0 0.0023 13 0 0 0 9.81E+06 5.14E+06 - - - 2.5993 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19706.19706.2 0.000528 18-Nov K.SVLIGEFLEK.V "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1133.6332 0.89 33830 19706 2 1133.633689 567.8239 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 3713.1 - 598516 - - - 0.4084 - 1.977 0.468 - 411.8 1 2 0 0.0005 10 0 0 0 9.78E+07 1.10E+08 - - - 4.4 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.19708.19708.3 0.00886 Dec-36 K.LTLLTLHFPR.L "sp|Q92889|XPF_HUMAN,tr|A0A804HKF9|A0A804HKF9_HUMAN" 2 1209.7234 2.63 33832 19708 3 1209.72698 404.2484 DNA repair endonuclease XPF OS=Homo sapiens OX=9606 GN=ERCC4 PE=1 SV=3 9.76 3713.3 - 449617 - - - 2.9767 - 2.344 0.407 - 155 1 2 0 0.0036 10 0 0 0 2.99E+06 1.14E+06 - - - 5.5644 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19710.19710.2 0.000498 24-Sep K.FIQVSYLESGIVR.G "sp|Q13459|MYO9B_HUMAN,tr|M0R300|M0R300_HUMAN,tr|M0R0P8|M0R0P8_HUMAN" 3 1509.8191 999 33834 19710 2 1509.821822 755.9168 Unconventional myosin-IXb OS=Homo sapiens OX=9606 GN=MYO9B PE=1 SV=3 6 3713.6 - 199056 - - - 1.7837 - 1.853 0.376 - 192.1 1 2 0 0.0027 13 0 0 0 1.35E+06 0.00E+00 - - - 3.4003 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.19714.19714.2 0.54 18-Jul R.TLLLDGNPFR.V sp|Q9H9A6|LRC40_HUMAN 1 1144.6241 0.69 33837 19714 2 1144.626367 573.3193 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.5 3714.1 - 4.05E+06 - - - 2.0173 - 1.448 0.216 - 122.7 1 2 0 0.0023 10 0 0 0 1.63E+07 2.37E+07 - - - 1.6689 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19716.19716.2 0.00584 16-Nov K.TLFPLIEAK.K sp|P13010|XRCC5_HUMAN 1 1030.6063 1.06 33838 19716 2 1030.608591 516.3104 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.66 3714.3 - 4.34E+06 - - - 2.2395 - 1.683 0.317 - 332 1 2 0 0.0023 9 0 0 0 3.22E+08 3.04E+08 - - - 2.8877 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19717.19717.2 0.000176 16-Oct K.TMTLFSALR[166.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 1048.5615 1.02 33839 19717 2 1048.563694 525.288 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.41 3714.4 - 761800 - - - 2.1191 - 1.931 0.426 - 401.8 1 2 0 0.0022 9 0 0 0 7.77E+06 7.63E+06 - - - 4.0905 0.9555 230117_WJC_METTL3_WT_vs_EV_F04.19718.19718.2 0.0275 14-Jun R.NIPMLFVR.G sp|P62310|LSM3_HUMAN 1 988.5528 1.85 33840 19718 2 988.559479 495.2837 U6 snRNA-associated Sm-like protein LSm3 OS=Homo sapiens OX=9606 GN=LSM3 PE=1 SV=2 9.75 3714.6 - 737107 - - - 6.7482 - 1.196 0.286 - 99.1 1 2 0 0.0067 8 0 0 0 3.77E+07 2.04E+07 - - - 1.6911 0.9073 230117_WJC_METTL3_WT_vs_EV_F04.19721.19721.2 0.11 12-Aug L.PDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 956.4744 2.18 33843 19721 2 956.477969 479.2445 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 6.27 3714.9 - 425260 - - - 3.7617 - 1.783 0.349 - 261.6 1 1 0 0.0036 7 0 0 0 5.32E+07 2.44E+07 - - - 3.45 1 230117_WJC_METTL3_WT_vs_EV_F04.19724.19724.2 3.37E-05 13/24 A.TLSPTAVLILGPK.V "sp|Q8TDL5|BPIB1_HUMAN,tr|A2A2R0|A2A2R0_HUMAN" 2 1308.8017 999 33846 19724 2 1308.801948 655.4081 BPI fold-containing family B member 1 OS=Homo sapiens OX=9606 GN=BPIFB1 PE=1 SV=1 8.41 3715.3 - 240572 - - - 0.1987 - 2.614 0.551 - 463 1 1 0 0.0003 13 0 0 0 3.30E+06 0.00E+00 - - - 5.5767 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.19725.19725.2 0.00976 12-Jun K.DAFLVFR[166.11].S "sp|Q9Y6D6|BIG1_HUMAN,sp|Q9Y6D5|BIG2_HUMAN,tr|A0A7P0T7Z2|A0A7P0T7Z2_HUMAN,tr|A0A7P0T9L9|A0A7P0T9L9_HUMAN,tr|A0A7P0TA34|A0A7P0TA34_HUMAN,tr|A0A7P0T9L6|A0A7P0T9L6_HUMAN" 6 876.4733 1.35 33847 19725 2 876.474509 439.2439 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens OX=9606 GN=ARFGEF1 PE=1 SV=2 5.84 3715.5 - 237925 - - - 1.3703 - 1.448 0.306 - 140.7 1 2 0 0.0012 7 0 0 0 2.49E+06 1.84E+06 - - - 2.4737 0.8466 230117_WJC_METTL3_WT_vs_EV_F04.19726.19726.3 0.854 Jul-44 K.ALEDAFLAIDAK.L sp|O15355|PPM1G_HUMAN 1 1275.6711 -1 33848 19726 3 1275.674995 426.231 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.03 3715.6 - 84340 - - - 3.0784 - 1.227 0.089 - 48.5 1 2 0 0.0039 12 0 0 0 0.00E+00 0.00E+00 - - - 0.0982 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19730.19730.2 0.00618 18-Jul K.ELLGQGLLLR[166.11].S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1120.6844 0.94 33851 19730 2 1120.68641 561.3495 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3716.1 - 5.54E+06 - - - 1.8257 - 1.809 0.289 - 177.8 1 2 0 0.002 10 0 0 0 1.91E+08 2.03E+08 - - - 2.8295 1 230117_WJC_METTL3_WT_vs_EV_F04.19731.19731.2 1.86E-06 13/22 K.ALEDAFLAIDAK.L sp|O15355|PPM1G_HUMAN 1 1275.6711 2.91 33852 19731 2 1275.672765 638.8428 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.03 3716.2 - 4.74E+06 - - - 1.3303 - 2.492 0.536 - 490.1 1 2 0 0.0017 12 0 0 0 3.48E+07 1.20E+07 - - - 5.4018 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.19733.19733.2 0.000484 18-Nov R.GPILLPYQFR.M "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1202.6812 0.91 33854 19733 2 1202.687432 602.3479 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 8.75 3716.4 - 1.34E+06 - - - 5.1992 - 2.115 0.421 - 505.4 1 2 0 0.0063 10 0 0 0 9.76E+06 1.08E+07 - - - 4.2394 0.999 230117_WJC_METTL3_WT_vs_EV_F04.19734.19734.2 0.132 14-Jul R.LSLELFGR.V "sp|O95071|UBR5_HUMAN,tr|E5RFK7|E5RFK7_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 933.5284 1.88 33855 19734 2 933.530178 467.7715 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 6 3716.5 - 1.01E+06 - - - 1.94 - 1.594 0.277 - 136.6 1 2 0 0.0018 8 0 0 0 3.09E+07 1.65E+07 - - - 2.4925 0.9965 230117_WJC_METTL3_WT_vs_EV_F04.19738.19738.2 0.0592 12-Jun K.DAFLVFR.S "sp|Q9Y6D6|BIG1_HUMAN,sp|Q9Y6D5|BIG2_HUMAN,tr|A0A7P0T7Z2|A0A7P0T7Z2_HUMAN,tr|A0A7P0T9L9|A0A7P0T9L9_HUMAN,tr|A0A7P0TA34|A0A7P0TA34_HUMAN,tr|A0A7P0T9L6|A0A7P0T9L6_HUMAN" 6 866.465 1.35 33859 19738 2 866.464767 434.2398 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens OX=9606 GN=ARFGEF1 PE=1 SV=2 5.84 3717 - 345464 - - - -0.3128 - 1.288 0.256 - 108.4 1 2 0 -0.0003 7 0 0 0 2.49E+06 1.84E+06 - - - 1.7337 0.9014 230117_WJC_METTL3_WT_vs_EV_F04.19743.19743.2 0.051 12-Sep L.PDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 946.4661 1.47 33862 19743 2 946.465177 474.2403 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 6.27 3717.7 - 2.33E+06 - - - -0.9763 - 1.857 0.295 - 322 1 1 0 -0.0009 7 0 0 0 3.55E+07 2.41E+07 - - - 3.1808 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19744.19744.2 0.86 20-Oct R.VLLQAFDVVER[166.11].S sp|Q15750|TAB1_HUMAN 1 1297.727 0.5 33863 19744 2 1297.727069 649.8708 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 OS=Homo sapiens OX=9606 GN=TAB1 PE=1 SV=1 4.37 3717.8 - 1.96E+06 - - - 0.0863 - 2.15 0.297 - 334.3 2 2 0 0.0001 11 0 0 0 1.92E+07 3.85E+07 - - - 3.1709 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19745.19745.2 0.00383 18-Oct R.GPILLPYQFR[166.11].M "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1212.6894 0.93 33864 19745 2 1212.691816 607.352 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 8.75 3717.9 - 1.93E+06 - - - 1.9519 - 2.214 0.347 - 372.1 1 2 0 0.0024 10 0 0 0 1.00E+07 1.08E+07 - - - 3.8217 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19747.19747.2 0.000516 20-Nov K.ALLLSSVLSEK.G "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1158.686 2.68 33866 19747 2 1158.686436 580.3503 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 6.05 3718.2 - 1.22E+06 - - - 0.3849 - 2.359 0.383 - 351.2 1 2 0 0.0004 11 0 0 0 1.84E+07 6.88E+06 - - - 4.1914 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19748.19748.2 0.0167 16/22 K.LANILFTQELAR[166.11].R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1397.7906 1.47 33867 19748 2 1397.791361 699.9026 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3718.3 - 1.19E+06 - - - 0.5301 - 2.78 0.28 - 1163.8 1 2 0 0.0007 12 0 0 0 3.40E+07 2.31E+07 - - - 3.7991 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19749.19749.2 0.0462 13/22 K.LANILFTQELAR.R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1387.7823 1.47 33868 19749 2 1387.781725 694.8985 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3718.4 - 1.06E+06 - - - -0.4504 - 2.924 0.252 - 706.6 1 2 0 -0.0006 12 0 0 0 3.40E+07 2.31E+07 - - - 3.7252 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19750.19750.2 0.00625 18-Oct R.VDLPLAVLSK.M "sp|Q9H773|DCTP1_HUMAN,tr|H3BSA6|H3BSA6_HUMAN" 2 1053.6434 11.26 33869 19750 2 1053.647393 527.829 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 5.81 3718.6 - 1.04E+06 - - - 3.7926 - 2.145 0.428 - 214.8 1 2 0 0.004 10 0 0 0 5.53E+07 4.91E+06 - - - 4.3311 0.9743 230117_WJC_METTL3_WT_vs_EV_F04.19752.19752.2 0.0125 18-Sep K.NIFSVPEIVR.E "sp|O60645|EXOC3_HUMAN,tr|D6RB59|D6RB59_HUMAN" 2 1172.6554 2.14 33871 19752 2 1172.649688 587.335 Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3 6 3718.8 - 751066 - - - -4.836 - 1.554 0.307 - 239.3 1 2 0 -0.0057 10 0 0 0 9.55E+06 4.47E+06 - - - 2.5372 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.19753.19753.2 0.132 14-Sep R.MGLLAVLR.S "sp|O95394|AGM1_HUMAN,tr|D6RF77|D6RF77_HUMAN,tr|D6RC77|D6RC77_HUMAN,tr|D6RCQ8|D6RCQ8_HUMAN,tr|A0A494C099|A0A494C099_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C163|A0A494C163_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|D6RCD1|D6RCD1_HUMAN" 9 871.5313 2.04 33872 19753 2 871.534631 436.7729 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 9.5 3719 - 618322 - - - 3.7715 - 1.73 0.359 - 258.6 1 2 0 0.0033 8 0 0 0 6.66E+06 3.26E+06 - - - 3.3447 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.19754.19754.2 0.355 20-Oct K.ALLLSSVLSEK[136.11].G "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1166.7002 2.68 33873 19754 2 1166.704678 584.3574 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 6.05 3719.1 - 460273 - - - 3.8467 - 2.197 0.247 - 238.3 1 2 0 0.0045 11 0 0 0 1.84E+07 6.88E+06 - - - 2.9932 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19759.19759.2 0.0128 18-Sep K.ELLGQGLLLR.S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1110.6761 0.94 33877 19759 2 1110.676978 556.3453 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3719.5 - 7.68E+07 - - - 0.7959 - 1.869 0.318 - 347.1 1 2 0 0.0009 10 0 0 0 1.91E+08 2.03E+08 - - - 3.1352 0.999 230117_WJC_METTL3_WT_vs_EV_F04.19761.19761.2 0.0257 14-Jul R.LSLELFGR[166.11].V "sp|O95071|UBR5_HUMAN,tr|E5RFK7|E5RFK7_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 943.5366 1.87 33878 19761 2 943.536735 472.7756 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 6 3719.6 - 9.24E+06 - - - 0.1039 - 1.764 0.275 - 142.8 1 2 0 0.0001 8 0 0 0 3.09E+07 1.65E+07 - - - 2.7839 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19763.19763.2 0.00746 16-Jul R.ILDTLGLLR[166.11].Q "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN,tr|A0A087WWF4|A0A087WWF4_HUMAN" 3 1022.6364 1.14 33880 19763 2 1022.637527 512.3255 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 5.84 3719.7 - 3.61E+06 - - - 1.15 - 1.586 0.363 - 91.3 1 2 0 0.0012 9 0 0 0 2.80E+07 2.45E+07 - - - 3.0561 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19765.19765.2 0.166 16-Jul R.ILDTLGLLR.Q "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN,tr|A0A087WWF4|A0A087WWF4_HUMAN" 3 1012.6281 1.15 33882 19765 2 1012.629343 507.3213 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 5.84 3719.9 - 2.94E+06 - - - 1.2463 - 1.762 0.376 - 103.9 1 2 0 0.0013 9 0 0 0 2.81E+07 2.45E+07 - - - 3.4565 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.19772.19772.2 0.0518 14-Jun R.LAWALALR.G sp|Q92621|NU205_HUMAN 1 912.5545 2.36 33889 19772 2 912.554518 457.2845 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 9.75 3720.4 - 2.00E+06 - - - -0.0044 - 1.702 0.255 - 91.8 1 2 0 0 8 0 0 0 7.97E+06 3.38E+06 - - - 2.5283 1 230117_WJC_METTL3_WT_vs_EV_F04.19774.19774.2 7.80E-08 20-Nov K.SFYGSTLFLC[160.03]R.R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1349.6438 1.76 33891 19774 2 1349.646552 675.8292 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 7.94 3720.5 - 1.61E+06 - - - 2.0331 - 2.225 0.514 - 373.9 1 2 0 0.0027 11 0 0 0 8.74E+06 4.97E+06 - - - 5.0001 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19778.19778.2 0.000179 20-Aug K.IESLPPLLIGK[136.11].F "sp|Q8N9N7|LRC57_HUMAN,tr|A0A3B3ISV5|A0A3B3ISV5_HUMAN,tr|H3BSW0|H3BSW0_HUMAN" 3 1186.7417 2.39 33894 19778 2 1186.743169 594.3781 Leucine-rich repeat-containing protein 57 OS=Homo sapiens OX=9606 GN=LRRC57 PE=1 SV=1 6 3721 - 424290 - - - 1.2707 - 1.667 0.469 - 156 1 2 0 0.0015 11 0 0 0 1.12E+07 4.71E+06 - - - 3.887 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19780.19780.2 0.000147 20-Dec R.VLLQAFDVVER.S sp|Q15750|TAB1_HUMAN 1 1287.7187 0.5 33896 19780 2 1287.719492 644.8666 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 OS=Homo sapiens OX=9606 GN=TAB1 PE=1 SV=1 4.37 3721.2 - 2.13E+06 - - - 0.6251 - 2.573 0.248 - 547.9 1 2 0 0.0008 11 0 0 0 1.92E+07 3.85E+07 - - - 3.4291 0.9594 230117_WJC_METTL3_WT_vs_EV_F04.19783.19783.3 0.000381 Dec-48 R.GAAGALLVYDITR.R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1318.7245 1.28 33899 19783 3 1318.727338 440.5821 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3721.5 - 975343 - - - 2.1513 - 2.002 0.022 - 240.1 1 2 0 0.0028 13 0 0 0 6.45E+06 5.03E+06 - - - 0.6665 0.9916 230117_WJC_METTL3_WT_vs_EV_F04.19784.19784.2 0.351 12-Jun R.LQLWAFK.L sp|Q9Y613|FHOD1_HUMAN 1 904.5171 -1 33900 19784 2 904.517183 453.2658 FH1\FH2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FHOD1 PE=1 SV=3 8.75 3721.6 - 910340 - - - 0.1205 - 1.407 0.096 - 103.9 1 2 0 0.0001 7 0 0 0 0.00E+00 0.00E+00 - - - 0.832 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.19785.19785.2 0.0228 20-Sep K.SFYGSTLFLC[160.03]R[166.11].R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1359.6521 1.76 33901 19785 2 1359.653883 680.8333 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 7.94 3721.8 - 790393 - - - 1.3275 - 1.589 0.341 - 237 1 2 0 0.0018 11 0 0 0 8.74E+06 4.97E+06 - - - 2.8119 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19786.19786.2 0.0129 24-Dec R.LVDIIAAVPPQYR.K "sp|Q9H9T3|ELP3_HUMAN,tr|E5RIZ7|E5RIZ7_HUMAN,tr|E5RIC0|E5RIC0_HUMAN,tr|E5RHY2|E5RHY2_HUMAN,tr|E5RHR2|E5RHR2_HUMAN" 5 1453.8293 1.58 33902 19786 2 1453.833232 727.9219 Elongator complex protein 3 OS=Homo sapiens OX=9606 GN=ELP3 PE=1 SV=2 5.84 3721.9 - 693681 - - - 2.7046 - 2.542 0.393 - 491.6 1 2 0 0.0039 13 0 0 0 6.63E+06 4.19E+06 - - - 4.3369 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19788.19788.2 0.0048 16-Aug K.FFPLIEVNK.V "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1105.6172 0.82 33903 19788 2 1105.618076 553.8159 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6 3722.1 - 1.03E+07 - - - 0.8086 - 1.394 0.359 - 181.9 1 2 0 0.0009 9 0 0 0 2.39E+08 2.92E+08 - - - 2.6533 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19790.19790.2 8.67E-08 15/24 R.GAAGALLVYDITR[166.11].R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1328.7328 0.95 33904 19790 2 1328.732728 665.3737 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3722.3 - 372128 - - - -0.0324 - 3.428 0.172 - 1095.3 1 2 0 0 13 0 0 0 7.55E+07 7.92E+07 - - - 3.4733 1 230117_WJC_METTL3_WT_vs_EV_F04.19792.19792.2 0.00223 13/22 K.IYDALDVSLIER.G sp|P54136|SYRC_HUMAN 1 1405.7453 1.45 33906 19792 2 1405.74357 703.8799 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.03 3722.4 - 204001 - - - -1.2278 - 2.684 0.593 - 688.4 1 2 0 -0.0017 12 0 0 0 2.81E+07 1.94E+07 - - - 6.0181 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19794.19794.2 0.000332 18-Oct R.NVEELVIVLK[136.11].K "sp|P53618|COPB_HUMAN,tr|E9PP73|E9PP73_HUMAN" 2 1162.7053 3.36 33908 19794 2 1162.707796 582.3599 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 4.53 3722.6 - 0 - - - 2.1682 - 1.791 0.475 - 241.3 1 2 0 0.0025 10 0 0 0 1.34E+07 3.99E+06 - - - 4.1753 1 230117_WJC_METTL3_WT_vs_EV_F04.19799.19799.2 0.00138 13/22 K.IYDALDVSLIER[166.11].G sp|P54136|SYRC_HUMAN 1 1415.7536 1.45 33911 19799 2 1415.75423 708.8841 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.03 3723.2 - 411304 - - - 0.469 - 2.595 0.533 - 613.9 1 2 0 0.0007 12 0 0 0 2.81E+07 1.94E+07 - - - 5.4866 0.9779 230117_WJC_METTL3_WT_vs_EV_F04.19800.19800.2 0.000175 22-Nov K.PYRPWGTEIGAF.- "sp|Q9Y5J3|HEY1_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 4 1392.6826 3.17 33912 19800 2 1392.684458 697.3486 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 6.43 3723.3 - 932653 - - - 1.3083 - 1.998 0.457 - 365.8 1 1 0 0.0018 12 0 0 0 1.41E+07 4.45E+06 - - - 4.237 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19801.19801.2 6.50E-05 22-Dec K.YLGPAVLMQAYR.W sp|P21912|SDHB_HUMAN 1 1380.7224 2.69 33913 19801 2 1380.726177 691.3685 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 8.59 3723.5 - 547204 - - - 2.7413 - 1.963 0.466 - 386.4 1 2 0 0.0038 12 0 0 0 1.11E+07 4.12E+06 - - - 4.2563 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19802.19802.2 0.000339 18-Oct K.GIYLWDVEGR.K sp|P04181|OAT_HUMAN 1 1206.6033 1.31 33914 19802 2 1206.603811 604.3089 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.37 3723.6 - 425696 - - - 0.4044 - 2.003 0.487 - 349.8 1 2 0 0.0005 10 0 0 0 9.04E+06 6.90E+06 - - - 4.5768 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19803.19803.2 0.00103 18-Oct K.GIYLWDVEGR[166.11].K sp|P04181|OAT_HUMAN 1 1216.6116 1.31 33915 19803 2 1216.613456 609.3131 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.37 3723.7 - 395409 - - - 1.5313 - 1.877 0.436 - 292.6 1 2 0 0.0019 10 0 0 0 9.04E+06 6.90E+06 - - - 4.0183 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.19804.19804.2 0.0063 18-Aug R.LVLVNAVYFR.G "sp|P35237|SPB6_HUMAN,tr|A0A087X1N8|A0A087X1N8_HUMAN,tr|A0A2R8Y6A7|A0A2R8Y6A7_HUMAN,tr|A0A024QZX5|A0A024QZX5_HUMAN,tr|A0A2R8YD12|A0A2R8YD12_HUMAN" 5 1192.6968 -1 33916 19804 2 1192.702278 597.3557 Serpin B6 OS=Homo sapiens OX=9606 GN=SERPINB6 PE=1 SV=3 8.75 3723.8 - 306347 - - - 4.5686 - 1.911 0.346 - 134.9 1 2 0 0.0054 10 0 0 0 0.00E+00 0.00E+00 - - - 3.4026 1 230117_WJC_METTL3_WT_vs_EV_F04.19806.19806.2 2.60E-06 14/24 K.LDNLLLDTEGYVK.L "sp|Q16512|PKN1_HUMAN,tr|K7EL10|K7EL10_HUMAN" 2 1491.7821 3.3 33918 19806 2 1491.786028 746.8983 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 4.03 3724.1 - 0 - - - 2.6499 - 2.747 0.405 - 521.8 1 2 0 0.004 13 0 0 0 3.27E+06 9.92E+05 - - - 4.6246 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19811.19811.2 0.00547 14-Aug K.IPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1059.5502 1.26 33921 19811 2 1059.552712 530.7824 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3724.6 - 2.29E+08 - - - 2.4039 - 1.691 0.481 - 372.4 1 2 0 0.0025 8 0 0 0 4.96E+09 3.93E+09 - - - 4.1772 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.19812.19812.2 0.04 14-Aug R.NLIEWLNK[136.11].Y sp|Q96DG6|CMBL_HUMAN 1 1036.5797 0.84 33922 19812 2 1036.581661 519.2971 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 6 3724.7 - 1.70E+07 - - - 1.9101 - 1.63 0.275 - 234.1 1 2 0 0.002 8 0 0 0 1.48E+08 1.76E+08 - - - 2.5451 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.19813.19813.2 0.0582 14-Jul R.NLIEWLNK.Y sp|Q96DG6|CMBL_HUMAN 1 1028.5655 0.84 33923 19813 2 1028.56733 515.29 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 6 3724.7 - 1.34E+07 - - - 1.7976 - 1.523 0.2 - 176.7 1 2 0 0.0019 8 0 0 0 1.48E+08 1.77E+08 - - - 1.7864 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19814.19814.2 0.301 18-Jul K.IINFAPSLLR[166.11].L "sp|O15397|IPO8_HUMAN,tr|F5H2I3|F5H2I3_HUMAN" 2 1152.6894 1.2 33924 19814 2 1152.691133 577.352 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 9.75 3724.8 - 1.77E+06 - - - 1.4609 - 1.746 0.268 - 162.9 1 2 0 0.0017 10 0 0 0 4.21E+07 3.50E+07 - - - 2.5756 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.19816.19816.2 1.53E-05 14/24 R.AGLNGLQLAVLAR.L sp|Q96S55|WRIP1_HUMAN 1 1294.7721 5.59 33926 19816 2 1294.771911 648.3933 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 9.79 3725 - 913896 - - - -0.1614 - 2.431 0.205 - 765.7 1 2 0 -0.0002 13 0 0 0 1.11E+07 1.98E+06 - - - 2.8349 1 230117_WJC_METTL3_WT_vs_EV_F04.19817.19817.2 9.92E-09 13/26 K.FYGPAGPYGIFAGR[166.11].D sp|O15173|PGRC2_HUMAN 1 1481.7331 1.26 33927 19817 2 1481.734916 741.8738 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3725.1 - 614516 - - - 1.2222 - 2.158 0.634 - 577.8 1 2 0 0.0018 14 0 0 0 9.24E+06 7.30E+06 - - - 5.6534 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.19818.19818.2 0.251 12-Jul R.WLSQYID.- "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 923.4389 - 33928 19818 2 923.440351 462.7267 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.3 3725.2 - 592435 - - - 1.5897 - 1.122 0.254 - 106.4 1 2 0 0.0015 7 0 0 0 - - - - - 1.2813 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19822.19822.2 0.0174 14-Sep K.IPDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1069.5584 1.26 33931 19822 2 1069.558515 535.7865 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3725.7 - 8.37E+07 - - - 0.0748 - 1.855 0.449 - 494.4 1 2 0 0.0001 8 0 0 0 4.96E+09 3.93E+09 - - - 4.2208 1 230117_WJC_METTL3_WT_vs_EV_F04.19824.19824.3 4.91E-08 13/60 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 108.62 33932 19824 3 1787.006648 596.6753 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3726 - 3.40E+06 - - - 1.465 - 3.037 0.614 - 302.1 1 2 0 0.0026 16 0 0 0 2.00E+08 1.84E+06 - - - 8.2351 0.9037 230117_WJC_METTL3_WT_vs_EV_F04.19825.19825.2 0.0358 14-Jun R.DIIC[160.03]QIAY.A "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 994.4794 - 33933 19825 2 994.480498 498.247 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 3.8 3726 - 1.91E+06 - - - 1.1363 - 1.292 0.309 - 158.2 1 1 0 0.0011 8 0 0 0 - - - - - 2.0956 1 230117_WJC_METTL3_WT_vs_EV_F04.19826.19826.2 4.61E-06 20-Nov K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 -1 33934 19826 2 1184.714004 593.3637 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3726.1 - 1.61E+06 - - - 0.9547 - 2.376 0.541 - 451.7 1 2 0 0.0011 11 0 0 0 0.00E+00 0.00E+00 - - - 5.3776 0.9947 230117_WJC_METTL3_WT_vs_EV_F04.19827.19827.2 0.341 12-Jul K.LLDDLFR[166.11].K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 900.4944 1.04 33935 19827 2 900.494039 451.2545 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3726.1 - 1.44E+06 - - - -0.4431 - 1.41 0.176 - 166.4 1 2 0 -0.0004 7 0 0 0 2.02E+08 1.94E+08 - - - 1.4295 0.9917 230117_WJC_METTL3_WT_vs_EV_F04.19828.19828.2 0.561 20-May R.NAVLAIYTIYR.N "sp|P53618|COPB_HUMAN,tr|E9PP73|E9PP73_HUMAN" 2 1295.7238 4.33 33936 19828 2 1295.724315 648.8692 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 8.59 3726.1 - 915514 - - - 0.4191 - 1.256 0.146 - 100.7 1 2 0 0.0005 11 0 0 0 4.08E+07 9.41E+06 - - - 0.7358 0.9916 230117_WJC_METTL3_WT_vs_EV_F04.19830.19830.2 0.0107 14-Jun R.SLPVFPFR[166.11].E "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 971.5468 1.4 33938 19830 2 971.546157 486.7807 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 9.47 3726.4 - 649190 - - - -0.6701 - 1.184 0.22 - 125 1 2 0 -0.0007 8 0 0 0 5.97E+06 4.26E+06 - - - 1.1751 0.9944 230117_WJC_METTL3_WT_vs_EV_F04.19831.19831.2 0.000302 18-Sep R.LNDYIFSFDK[136.11].M sp|P54136|SYRC_HUMAN 1 1268.6169 1.21 33939 19831 2 1268.611776 635.3157 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.21 3726.4 - 597952 - - - -4.0028 - 2.038 0.405 - 429.4 1 2 0 -0.0051 10 0 0 0 5.29E+06 4.36E+06 - - - 4.0181 0.9963 230117_WJC_METTL3_WT_vs_EV_F04.19832.19832.2 0.0109 24-Oct R.LLLFSSATDAAIR[166.11].V "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1386.7746 0.47 33940 19832 2 1386.781769 694.3946 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.84 3726.5 - 586624 - - - 5.1436 - 1.803 0.37 - 286.1 1 2 0 0.0071 13 0 0 0 1.16E+07 2.47E+07 - - - 3.2844 0.9962 230117_WJC_METTL3_WT_vs_EV_F04.19833.19833.2 0.379 14-May R.SLPVFPFR.E "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 961.5385 1.33 33941 19833 2 961.539763 481.7765 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 9.47 3726.6 - 522986 - - - 1.274 - 1.152 0.233 - 128.6 1 2 0 0.0012 8 0 0 0 8.90E+06 6.71E+06 - - - 1.1883 1 230117_WJC_METTL3_WT_vs_EV_F04.19837.19837.2 0.000234 14/20 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 148.24 33944 19837 2 1276.703622 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3727 - 1.18E+08 - - - 0.7198 - 2.757 0.404 - 983 1 2 0 0.0009 11 0 0 0 8.06E+08 5.44E+06 - - - 4.7682 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19839.19839.2 0.0109 18-Oct R.AAFVLPEFAR.K "sp|P19623|SPEE_HUMAN,tr|K7EL89|K7EL89_HUMAN" 2 1119.6077 5.58 33945 19839 2 1119.607722 560.8111 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 6.05 3727.2 - 3.01E+06 - - - 0.0375 - 1.955 0.395 - 248.7 1 2 0 0 10 0 0 0 7.61E+07 1.36E+07 - - - 3.8297 0.9965 230117_WJC_METTL3_WT_vs_EV_F04.19840.19840.2 0.281 12-Jul K.LLDDLFR.K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 890.4862 1.04 33946 19840 2 890.486795 446.2504 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3727.3 - 6.32E+06 - - - 0.7041 - 1.321 0.188 - 171 1 2 0 0.0006 7 0 0 0 2.02E+08 1.94E+08 - - - 1.3115 1 230117_WJC_METTL3_WT_vs_EV_F04.19841.19841.2 1.11E-07 24/30 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 999 33947 19841 2 1787.006319 894.5093 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3727.4 - 2.90E+06 - - - 1.2809 - 4.543 0.583 - 1686.6 1 2 0 0.0023 16 0 0 0 4.04E+07 0.00E+00 - - - 7.0675 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.19844.19844.2 0.0262 20-Nov -.MLLFVEQVASK.G "sp|Q71RC2|LARP4_HUMAN,tr|F8W1Z5|F8W1Z5_HUMAN" 2 1263.6897 0.35 33950 19844 2 1263.694409 632.8521 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 5.75 3727.7 - 1.22E+06 - - - 3.7303 - 2.244 0.384 - 350.4 1 2 0 0.0047 11 0 0 0 1.68E+07 4.81E+07 - - - 4.0623 1 230117_WJC_METTL3_WT_vs_EV_F04.19847.19847.2 3.59E-05 16-Oct K.YDWDLLAAR[166.11].S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1131.5588 1.62 33953 19847 2 1131.562022 566.7867 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3728 - 968887 - - - 2.8218 - 2.013 0.512 - 387.1 1 2 0 0.0032 9 0 0 0 8.44E+07 5.19E+07 - - - 4.8457 1 230117_WJC_METTL3_WT_vs_EV_F04.19848.19848.2 1.39E-05 18-Nov R.QEVVDLLLAR[166.11].G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1164.6742 1.31 33954 19848 2 1164.672353 583.3444 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3728.1 - 744630 - - - -1.5798 - 2.256 0.49 - 541.7 1 2 0 -0.0018 10 0 0 0 8.73E+07 6.65E+07 - - - 4.9305 0.9708 230117_WJC_METTL3_WT_vs_EV_F04.19850.19850.2 5.02 14-Jul R.LIFLDSIK.S "sp|Q99996|AKAP9_HUMAN,tr|A0A0A0MRF6|A0A0A0MRF6_HUMAN,tr|A0A7P0TBH8|A0A7P0TBH8_HUMAN,tr|A0A7P0TAX3|A0A7P0TAX3_HUMAN,tr|A0A7P0T9A9|A0A7P0T9A9_HUMAN,tr|A0A7P0T8N5|A0A7P0T8N5_HUMAN,tr|A0A7P0TBI4|A0A7P0TBI4_HUMAN,tr|A0A7P0Z4Q5|A0A7P0Z4Q5_HUMAN,tr|A0A7P0Z4N5|A0A7P0Z4N5_HUMAN,tr|A0A7P0TAD6|A0A7P0TAD6_HUMAN,tr|A0A7P0T939|A0A7P0T939_HUMAN,tr|A0A7P0T928|A0A7P0T928_HUMAN,tr|A0A7P0TAA2|A0A7P0TAA2_HUMAN" 13 947.5692 1.29 33956 19850 2 947.568965 474.7919 A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4 5.84 3728.4 - 638607 - - - -0.2153 - 1.045 0.123 - 105.9 1 2 0 -0.0002 8 0 0 0 4.17E+06 3.22E+06 - - - 0.0822 0.921 230117_WJC_METTL3_WT_vs_EV_F04.19851.19851.2 0.0011 22-Nov K.LLQVASPFLEPH.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1349.7343 - 33957 19851 2 1349.738892 675.8744 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 5.24 3728.5 - 613996 - - - 3.3747 - 1.825 0.366 - 214.7 1 1 0 0.0046 12 0 0 0 - - - - - 3.3257 0.999 230117_WJC_METTL3_WT_vs_EV_F04.19854.19854.2 0.00882 24-Jul R.VETPVLPPVLVPR[166.11].H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1424.8631 1.83 33960 19854 2 1424.866254 713.4388 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3728.9 - 293193 - - - 2.2437 - 1.68 0.3 - 127.3 1 2 0 0.0032 13 0 0 0 1.34E+07 7.32E+06 - - - 2.5873 0.9208 230117_WJC_METTL3_WT_vs_EV_F04.19855.19855.2 0.0465 12-Sep F.PLIEVNK[136.11].V "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 819.4946 1.49 33961 19855 2 819.495547 410.7546 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6.43 3729 - 237001 - - - 1.2117 - 1.868 0.174 - 320.2 1 1 0 0.001 7 0 0 0 2.88E+06 1.94E+06 - - - 2.3058 0.999 230117_WJC_METTL3_WT_vs_EV_F04.19859.19859.2 0.00696 14-Aug R.DWVLNEFK.H "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1049.5182 1.57 33963 19859 2 1049.520409 525.7664 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3729.5 - 1.74E+06 - - - 2.1086 - 1.506 0.306 - 301.1 1 2 0 0.0022 8 0 0 0 1.08E+08 6.85E+07 - - - 2.5353 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19860.19860.2 4.91E-05 18-Nov R.QEVVDLLLAR.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1154.6659 1.31 33964 19860 2 1154.666776 578.3402 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3729.6 - 1.09E+06 - - - 0.7387 - 2.227 0.392 - 409.9 1 2 0 0.0009 10 0 0 0 8.73E+07 6.65E+07 - - - 4.1709 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19861.19861.3 0.0352 13/40 K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 7.88 33965 19861 3 1184.71395 395.9116 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3729.6 - 949651 - - - 0.9091 - 2.346 0.299 - 206.1 1 2 0 0.0011 11 0 0 0 6.60E+07 8.38E+06 - - - 4.2957 1 230117_WJC_METTL3_WT_vs_EV_F04.19862.19862.2 5.60E-09 15/26 K.FYGPAGPYGIFAGR.D sp|O15173|PGRC2_HUMAN 1 1471.7248 1.48 33966 19862 2 1471.726944 736.8697 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3729.7 - 929792 - - - 1.433 - 2.421 0.538 - 887.2 1 2 0 0.0021 14 0 0 0 2.48E+07 1.67E+07 - - - 5.2328 0.8734 230117_WJC_METTL3_WT_vs_EV_F04.19863.19863.3 2.56 Aug-40 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 4.45 33967 19863 3 1276.703253 426.5748 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3729.9 - 781578 - - - 0.4308 - 1.396 0.042 - 119.9 1 2 0 0.0006 11 0 0 0 4.39E+06 9.86E+05 - - - -0.0442 0.9103 230117_WJC_METTL3_WT_vs_EV_F04.19864.19864.2 5.74 14-May R.TELTPAYF.- sp|P09417|DHPR_HUMAN 1 940.4542 - 33968 19864 2 940.455035 471.2344 Dihydropteridine reductase OS=Homo sapiens OX=9606 GN=QDPR PE=1 SV=2 4 3730 - 508655 - - - 0.8889 - 0.861 0.062 - 52.1 1 2 0 0.0008 8 0 0 0 - - - - - -0.9527 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19866.19866.2 5.98E-05 20-Nov K.TYSYLTPDLWK.E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1385.6867 0.36 33970 19866 2 1385.689136 693.8506 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.5 3730.3 - 293654 - - - 1.745 - 2.075 0.458 - 333.1 1 2 0 0.0024 11 0 0 0 3.73E+06 1.03E+07 - - - 4.3977 1 230117_WJC_METTL3_WT_vs_EV_F04.19868.19868.2 1.75E-05 13/24 R.VETPVLPPVLVPR.H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1414.8548 1.83 33972 19868 2 1414.855476 708.4347 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3730.5 - 228888 - - - 0.487 - 2.264 0.545 - 313.9 1 2 0 0.0007 13 0 0 0 1.34E+07 7.32E+06 - - - 5.1633 0.9947 230117_WJC_METTL3_WT_vs_EV_F04.19869.19869.2 0.141 14-Jul R.LIFLDSIK[136.11].S "sp|Q99996|AKAP9_HUMAN,tr|A0A0A0MRF6|A0A0A0MRF6_HUMAN,tr|A0A7P0TBH8|A0A7P0TBH8_HUMAN,tr|A0A7P0TAX3|A0A7P0TAX3_HUMAN,tr|A0A7P0T9A9|A0A7P0T9A9_HUMAN,tr|A0A7P0T8N5|A0A7P0T8N5_HUMAN,tr|A0A7P0TBI4|A0A7P0TBI4_HUMAN,tr|A0A7P0Z4Q5|A0A7P0Z4Q5_HUMAN,tr|A0A7P0Z4N5|A0A7P0Z4N5_HUMAN,tr|A0A7P0TAD6|A0A7P0TAD6_HUMAN,tr|A0A7P0T939|A0A7P0T939_HUMAN,tr|A0A7P0T928|A0A7P0T928_HUMAN,tr|A0A7P0TAA2|A0A7P0TAA2_HUMAN" 13 955.5834 1.29 33973 19869 2 955.586825 478.799 A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4 5.84 3730.6 - 281723 - - - 3.6166 - 1.309 0.256 - 112.3 1 2 0 0.0035 8 0 0 0 4.17E+06 3.22E+06 - - - 1.7428 1 230117_WJC_METTL3_WT_vs_EV_F04.19872.19872.2 9.92E-06 20-Dec K.FDGILGMAYPR.L "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1238.6118 10.07 33976 19872 2 1238.613502 620.3132 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.84 3731 - 180642 - - - 1.3911 - 2.296 0.475 - 516.6 1 2 0 0.0017 11 0 0 0 2.23E+07 2.22E+06 - - - 4.7973 1 230117_WJC_METTL3_WT_vs_EV_F04.19873.19873.2 5.73E-07 15/24 R.AIVFVVDSAAFQR.E "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1421.7667 2.4 33977 19873 2 1421.765845 711.8906 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.88 3731.2 - 176952 - - - -0.6014 - 3.084 0.543 - 995.3 1 2 0 -0.0009 13 0 0 0 6.83E+06 2.85E+06 - - - 5.9418 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19875.19875.2 0.0128 18-Sep K.IINFAPSLLR.L "sp|O15397|IPO8_HUMAN,tr|F5H2I3|F5H2I3_HUMAN" 2 1142.6812 1.2 33978 19875 2 1142.684173 572.3479 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 9.75 3731.4 - 797318 - - - 2.6202 - 2.174 0.366 - 205.8 1 2 0 0.003 10 0 0 0 4.21E+07 3.50E+07 - - - 3.911 1 230117_WJC_METTL3_WT_vs_EV_F04.19877.19877.2 9.94E-06 16-Sep K.YDWDLLAAR.S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1121.5506 1.63 33979 19877 2 1121.552944 561.7826 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3731.6 - 4.17E+06 - - - 2.1265 - 1.894 0.542 - 348.6 1 2 0 0.0024 9 0 0 0 8.49E+07 5.19E+07 - - - 4.8912 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.19878.19878.2 0.407 16-Oct K.DGLLGAELR.L sp|P43026|GDF5_HUMAN 1 942.5134 6.49 33980 19878 2 942.517561 472.264 Growth\differentiation factor 5 OS=Homo sapiens OX=9606 GN=GDF5 PE=1 SV=3 4.37 3731.7 - 646795 - - - 4.367 - 1.855 0.245 - 217.1 1 2 0 0.0041 9 0 0 0 1.22E+07 1.88E+06 - - - 2.6369 0.9316 230117_WJC_METTL3_WT_vs_EV_F04.19884.19884.2 1.16 12-Jul K.DIILPFR.V "sp|Q96CW1|AP2M1_HUMAN,tr|A0A087WY71|A0A087WY71_HUMAN,tr|C9JJ47|C9JJ47_HUMAN,tr|E9PFW3|E9PFW3_HUMAN" 4 872.512 1.59 33986 19884 2 872.51611 437.2633 AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2 5.84 3732.5 - 193056 - - - 4.7231 - 1.497 0 - 195.8 1 2 0 0.0041 7 0 0 0 1.70E+07 1.07E+07 - - - 0.3181 0.9497 230117_WJC_METTL3_WT_vs_EV_F04.19888.19888.2 0.407 20-Jul K.FNIFYPDLIDK.R "sp|Q8WUQ7|CATIN_HUMAN,tr|K7EIU6|K7EIU6_HUMAN,tr|K7ENY9|K7ENY9_HUMAN" 3 1383.7075 -1 33988 19888 2 1383.720773 692.861 Cactin OS=Homo sapiens OX=9606 GN=CACTIN PE=1 SV=3 4.21 3733 - 690772 - - - 9.6256 - 2.043 0.222 - 190.6 2 2 0 0.0133 11 0 0 0 0.00E+00 0.00E+00 - - - 2.4747 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19889.19889.3 0.035 Nov-40 K.TAVETAVLLLR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1194.7211 7.88 33989 19889 3 1194.723603 399.2477 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3733.2 - 559607 - - - 2.0591 - 2.043 0.309 - 175.2 1 2 0 0.0025 11 0 0 0 6.60E+07 8.38E+06 - - - 4.0139 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.19891.19891.2 0.00119 14-Sep R.IWYLLDGK[136.11].M "sp|Q9BYD1|RM13_HUMAN,tr|E5RFI2|E5RFI2_HUMAN" 2 1014.563 0.83 33991 19891 2 1014.565994 508.2888 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 5.83 3733.3 - 1.49E+06 - - - 2.9826 - 1.821 0.429 - 288.1 1 2 0 0.003 8 0 0 0 1.20E+07 1.44E+07 - - - 4.0164 0.9909 230117_WJC_METTL3_WT_vs_EV_F04.19903.19903.2 0.0451 20-Sep R.IAIQGIITAIK.Y sp|Q6NSI4|RADX_HUMAN 1 1139.7278 2.16 34001 19903 2 1139.725537 570.8712 RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2 8.75 3734.7 - 1.00E+06 - - - -1.9812 - 1.362 0.262 - 134.4 1 2 0 -0.0023 11 0 0 0 6.04E+06 2.79E+06 - - - 1.8112 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.19906.19906.2 0.0155 12-Jul K.NMFAIWR.V "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 936.464 0.98 34004 19906 2 936.466336 469.2393 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3735.1 - 631242 - - - 2.502 - 1.309 0.293 - 219.2 1 2 0 0.0023 7 0 0 0 3.35E+07 3.40E+07 - - - 2.0575 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.19908.19908.2 1.58 12-Jul R.VTLLLFK.D "sp|Q9Y3C4|TPRKB_HUMAN,sp|Q86YN1|DOPP1_HUMAN,tr|H7C1Z8|H7C1Z8_HUMAN,tr|H7BXT6|H7BXT6_HUMAN" 4 832.5422 1.91 34006 19908 2 832.542576 417.2784 EKC\KEOPS complex subunit TPRKB OS=Homo sapiens OX=9606 GN=TPRKB PE=1 SV=1 8.72 3735.3 - 584190 - - - 0.4204 - 1.543 0.131 - 178.4 1 2 0 0.0003 7 0 0 0 3.67E+06 1.92E+06 - - - 1.3827 0.9639 230117_WJC_METTL3_WT_vs_EV_F04.19910.19910.2 0.00721 18-Sep K.GIGFLTSGWR.F sp|Q8IXM3|RM41_HUMAN 1 1092.5716 1 34008 19910 2 1092.582529 547.2931 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 9.75 3735.5 - 587371 - - - 9.9765 - 1.575 0.344 - 171 1 2 0 0.0109 10 0 0 0 2.61E+07 2.61E+07 - - - 2.8463 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19919.19919.2 0.00108 16-Jul R.GFFGFPGPR.S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 980.4868 1.76 34015 19919 2 980.488026 491.2507 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3736.7 - 311496 - - - 1.2127 - 1.438 0.42 - 120.6 1 2 0 0.0012 9 0 0 0 3.13E+06 1.77E+06 - - - 3.1937 0.9892 230117_WJC_METTL3_WT_vs_EV_F04.19924.19924.2 1.43 16-Jul R.LVLDPYLLK[136.11].Y "sp|Q9Y2R5|RT17_HUMAN,tr|I3L0E3|I3L0E3_HUMAN,tr|E9PE17|E9PE17_HUMAN" 3 1080.6674 0.93 34018 19924 2 1080.669324 541.341 "28S ribosomal protein S17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS17 PE=1 SV=1" 5.83 3737.3 - 4.29E+06 - - - 1.7498 - 1.024 0.199 - 94.8 2 2 0 0.0019 9 0 0 0 3.77E+07 4.05E+07 - - - 0.4444 1 230117_WJC_METTL3_WT_vs_EV_F04.19929.19929.2 1.49E-06 18-Oct R.LWGDIYFNPK.T sp|Q15029|U5S1_HUMAN 1 1251.6288 1.09 34023 19929 2 1251.631348 626.8217 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.83 3737.9 - 645649 - - - 2.0286 - 2.132 0.559 - 339.2 1 2 0 0.0025 10 0 0 0 9.05E+06 8.30E+06 - - - 5.2822 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19930.19930.2 0.000465 18-Sep R.LWGDIYFNPK[136.11].T sp|Q15029|U5S1_HUMAN 1 1259.643 0.98 34024 19930 2 1259.643933 630.8288 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.83 3738 - 493673 - - - 0.7335 - 1.834 0.487 - 208.8 1 2 0 0.0009 10 0 0 0 9.23E+06 9.46E+06 - - - 4.3306 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.19931.19931.2 0.00127 16-Jun R.GFFGFPGPR[166.11].S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 990.4951 1.79 34025 19931 2 990.497664 496.2548 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3738.1 - 340427 - - - 2.5815 - 1.303 0.362 - 93.5 1 2 0 0.0026 9 0 0 0 3.17E+06 1.77E+06 - - - 2.4796 0.862 230117_WJC_METTL3_WT_vs_EV_F04.19933.19933.2 0.00499 12-May K.DHIMEIF.S "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BMS0|H3BMS0_HUMAN,tr|H3BTC0|H3BTC0_HUMAN" 5 903.416 - 34027 19933 2 903.418715 452.7153 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 4.35 3738.4 - 1.19E+06 - - - 2.9621 - 1.215 0.353 - 73.8 1 1 0 0.0027 7 0 0 0 - - - - - 2.2645 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.19936.19936.2 0.000119 24-Dec R.ATVGILITTIASK.G "sp|Q92973|TNPO1_HUMAN,tr|A0A7P0T9C0|A0A7P0T9C0_HUMAN,tr|A0A7P0TBF0|A0A7P0TBF0_HUMAN,tr|A0A7P0T944|A0A7P0T944_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 5 1286.781 1.49 34030 19936 2 1286.778243 644.3978 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 8.8 3738.8 - 151572 - - - -2.106 - 2.272 0.453 - 336 1 2 0 -0.0027 13 0 0 0 3.03E+06 2.03E+06 - - - 4.4923 0.9935 230117_WJC_METTL3_WT_vs_EV_F04.19937.19937.2 0.0844 20-Nov R.YVDQVLQLVYK.D sp|P11717|MPRI_HUMAN 1 1366.7497 3.26 34031 19937 2 1366.75232 684.3821 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 5.83 3738.9 - 137864 - - - 1.9513 - 1.274 0.156 - 69.2 1 2 0 0.0027 11 0 0 0 3.31E+06 1.02E+06 - - - 0.8475 1 230117_WJC_METTL3_WT_vs_EV_F04.19938.19938.2 1.04E-08 14/22 K.LYDNLLEQNLIR.V sp|O00231|PSD11_HUMAN 1 1502.8093 1.81 34032 19938 2 1502.80879 752.4119 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3739.1 - 94177.5 - - - -0.3347 - 3.005 0.547 - 832.4 1 2 0 -0.0005 12 0 0 0 5.06E+07 2.80E+07 - - - 5.976 0.9594 230117_WJC_METTL3_WT_vs_EV_F04.19941.19941.2 0.000154 20-Sep K.FEQLVSIGSSY.N sp|Q9NXV2|KCTD5_HUMAN 1 1228.5976 - 34034 19941 2 1228.598822 615.3061 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4 3739.4 - 844685 - - - 1.0199 - 1.516 0.406 - 298.3 1 1 0 0.0013 11 0 0 0 - - - - - 3.1649 0.9972 230117_WJC_METTL3_WT_vs_EV_F04.19943.19943.2 0.206 16-Nov R.NLLGLALGR.L sp|Q8N5L8|RP25L_HUMAN 1 925.5709 1.19 34036 19943 2 925.572811 463.7927 Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1 9.75 3739.6 - 1.03E+06 - - - 2.0636 - 1.753 0.118 - 438.6 1 2 0 0.0019 9 0 0 0 5.35E+07 4.48E+07 - - - 1.5359 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19944.19944.2 0.00085 16-Oct K.SLTYLSILR[166.11].N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 3 1074.6313 1.2 34037 19944 2 1074.631656 538.3229 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 8.46 3739.7 - 637561 - - - 0.3629 - 1.915 0.447 - 399.9 1 2 0 0.0004 9 0 0 0 1.23E+07 1.03E+07 - - - 4.2221 1 230117_WJC_METTL3_WT_vs_EV_F04.19945.19945.2 0.000803 13/20 R.TLVLLDNLNVR[166.11].E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1278.7535 1.31 34038 19945 2 1278.756936 640.384 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3739.8 - 403731 - - - 2.6823 - 2.746 0.497 - 678.2 1 2 0 0.0034 11 0 0 0 5.53E+07 4.22E+07 - - - 5.4434 1 230117_WJC_METTL3_WT_vs_EV_F04.19947.19947.2 0.0574 16/28 R.LPLPSPALEYTLGSR.L sp|Q8IU81|I2BP1_HUMAN 1 1612.8825 2.73 34040 19947 2 1612.88915 807.4485 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3740.1 - 263933 - - - 4.1491 - 2.822 0.444 - 697.6 1 2 0 0.0067 15 0 0 0 4.65E+07 1.70E+07 - - - 4.8689 1 230117_WJC_METTL3_WT_vs_EV_F04.19950.19950.2 2.14E-08 14/22 K.LYDNLLEQNLIR[166.11].V sp|O00231|PSD11_HUMAN 1 1512.8176 1.81 34043 19950 2 1512.820176 757.4161 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3740.5 - 203598 - - - 1.7272 - 3.082 0.572 - 782.9 1 2 0 0.0026 12 0 0 0 5.06E+07 2.80E+07 - - - 6.2266 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19960.19960.2 0.000118 18-Oct K.GIGFLTSGWR[166.11].F sp|Q8IXM3|RM41_HUMAN 1 1102.5799 1 34051 19960 2 1102.582159 552.2972 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 9.75 3741.9 - 2.14E+06 - - - 2.0497 - 2.042 0.472 - 372.8 1 2 0 0.0023 10 0 0 0 2.61E+07 2.61E+07 - - - 4.5193 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.19961.19961.2 0.000151 20-Aug R.VFSWGFGGYGR.L sp|Q9P258|RCC2_HUMAN 1 1231.5774 2.03 34052 19961 2 1231.58053 616.796 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 8.72 3741.9 - 600951 - - - 2.5065 - 1.819 0.326 - 200.8 1 2 0 0.0031 11 0 0 0 9.87E+06 4.87E+06 - - - 3.0664 0.9479 230117_WJC_METTL3_WT_vs_EV_F04.19962.19962.2 7.16 16-Jun R.NLLGLALGR[166.11].L sp|Q8N5L8|RP25L_HUMAN 1 935.5792 1.2 34053 19962 2 935.580372 468.7969 Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1 9.75 3742 - 5.94E+06 - - - 1.2837 - 0.956 0.063 - 104.9 1 2 0 0.0012 9 0 0 0 5.36E+07 4.47E+07 - - - -0.6242 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.19963.19963.2 0.00322 16-Oct K.SLTYLSILR.N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 3 1064.623 1.15 34054 19963 2 1064.625301 533.3188 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 8.46 3742 - 2.29E+06 - - - 2.1651 - 1.94 0.477 - 414.3 1 2 0 0.0023 9 0 0 0 1.23E+07 1.07E+07 - - - 4.4806 1 230117_WJC_METTL3_WT_vs_EV_F04.19968.19968.2 1.88E-06 13/20 R.PMEVFMC[160.03]SVLK[136.11].R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1347.648 1.08 34059 19968 2 1347.650546 674.8313 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3742.6 - 627898 - - - 1.8618 - 2.492 0.523 - 581.5 1 1 0 0.0025 11 0 0 0 2.14E+07 1.99E+07 - - - 5.3732 0.9544 230117_WJC_METTL3_WT_vs_EV_F04.19970.19970.2 1.44 28-Jun R.LPLPSPALEYTLGSR[166.11].L sp|Q8IU81|I2BP1_HUMAN 1 1622.8907 2.73 34061 19970 2 1622.893371 812.4526 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3742.7 - 1.98E+06 - - - 1.6286 - 0.992 0.104 - 44.8 5 2 0 0.0026 15 0 0 0 4.65E+07 1.70E+07 - - - -0.5237 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.19973.19973.2 0.325 16-Aug R.GSLITSLLR[166.11].S sp|Q53FA7|QORX_HUMAN 1 968.5894 0.9 34064 19973 2 968.589761 485.302 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3743 - 350465 - - - 0.3717 - 1.717 0.288 - 144.9 1 2 0 0.0004 9 0 0 0 5.49E+06 6.09E+06 - - - 2.732 1 230117_WJC_METTL3_WT_vs_EV_F04.19975.19975.2 0.00786 20-Dec R.TLVLLDNLNVR.E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1268.7452 1.3 34065 19975 2 1268.747419 635.3799 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3743.2 - 2.09E+06 - - - 1.7206 - 2.405 0.472 - 587.3 1 2 0 0.0022 11 0 0 0 5.54E+07 4.28E+07 - - - 4.9005 1 230117_WJC_METTL3_WT_vs_EV_F04.19977.19977.2 6.54E-07 20-Nov R.PMEVFMC[160.03]SVLK.R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1339.6338 1.08 34067 19977 2 1339.635662 670.8242 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3743.3 - 1.20E+06 - - - 1.3623 - 2.235 0.557 - 400.4 1 1 0 0.0018 11 0 0 0 2.14E+07 1.99E+07 - - - 5.3301 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.19980.19980.2 0.000644 20-Dec R.VFSWGFGGYGR[166.11].L sp|Q9P258|RCC2_HUMAN 1 1241.5857 1.92 34070 19980 2 1241.588571 621.8001 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 8.72 3743.5 - 800854 - - - 2.3019 - 1.939 0.437 - 217.2 1 2 0 0.0029 11 0 0 0 9.34E+06 4.87E+06 - - - 4.0591 1 230117_WJC_METTL3_WT_vs_EV_F04.19982.19982.3 3.81E-12 28/76 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 3.02 34072 19982 3 2197.092287 733.3694 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3743.7 - 549091 - - - 2.745 - 4.587 0.649 - 1045.7 1 2 0 0.006 20 0 0 0 1.25E+07 4.13E+06 - - - 9.4694 1 230117_WJC_METTL3_WT_vs_EV_F04.19986.19986.2 6.31E-05 21/30 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 7.84 34076 19986 2 1549.888331 775.9487 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3744.2 - 242902 - - - 3.5738 - 3.133 0.502 - 1539 1 2 0 0.0055 16 0 0 0 3.39E+08 4.33E+07 - - - 5.5547 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.19995.19995.2 0.075 16-Aug R.GSLITSLLR.S sp|Q53FA7|QORX_HUMAN 1 958.5811 0.9 34083 19995 2 958.583584 480.2978 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3745.2 - 2.48E+06 - - - 2.559 - 1.688 0.22 - 155.6 1 2 0 0.0025 9 0 0 0 5.49E+06 6.09E+06 - - - 2.1798 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.19996.19996.2 0.0102 14-Aug R.LLC[160.03]ELFIR.A "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN,tr|C9JCJ2|C9JCJ2_HUMAN,tr|C9J053|C9J053_HUMAN" 7 1062.5896 1.28 34084 19996 2 1062.593264 532.3021 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.99 3745.3 - 2.33E+06 - - - 3.4604 - 1.705 0.335 - 206.2 1 2 0 0.0037 8 0 0 0 1.79E+07 1.39E+07 - - - 3.1234 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.19997.19997.2 0.0433 14-Aug R.YGLEC[160.03]LFR.Y "sp|Q6PKG0|LARP1_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN" 3 1056.5063 1.07 34085 19997 2 1056.509288 529.2604 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 5.99 3745.3 - 2.06E+06 - - - 2.8736 - 1.737 0.451 - 258.3 1 2 0 0.003 8 0 0 0 8.15E+06 7.59E+06 - - - 4.0364 0.9119 230117_WJC_METTL3_WT_vs_EV_F04.19998.19998.2 2 14-Apr R.YGLEC[160.03]LFR[166.11].Y "sp|Q6PKG0|LARP1_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN" 3 1066.5145 1.07 34086 19998 2 1066.517179 534.2645 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 5.99 3745.4 - 1.98E+06 - - - 2.4913 - 0.919 0.096 - 41.8 4 2 0 0.0027 8 0 0 0 8.15E+06 7.59E+06 - - - -0.7745 1 230117_WJC_METTL3_WT_vs_EV_F04.19999.19999.2 4.58E-14 24/38 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 -1 34087 19999 2 2197.092 1099.5504 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3745.5 - 1.61E+06 - - - 2.6144 - 4.369 0.764 - 1164.6 1 2 0 0.0057 20 0 0 0 0.00E+00 0.00E+00 - - - 8.3073 1 230117_WJC_METTL3_WT_vs_EV_F04.20006.20006.2 0.000255 15/26 R.LEALLEAADPEVLR.R tr|D6RHC4|D6RHC4_HUMAN 1 1537.8352 1.79 34094 20006 2 1537.840761 769.9249 Ankyrin repeat and KH domain-containing protein 1 (Fragment) OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4 3746.2 - 883274 - - - 3.633 - 2.681 0.497 - 657.6 1 2 0 0.0056 14 0 0 0 2.94E+06 1.64E+06 - - - 5.1849 1 230117_WJC_METTL3_WT_vs_EV_F04.20008.20008.2 0.0011 20/30 R.ALIAGGGAPEIELALR[166.11].L sp|P50991|TCPD_HUMAN 1 1559.8911 7.85 34096 20008 2 1559.89798 780.9528 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3746.5 - 829133 - - - 4.4349 - 3.046 0.471 - 1497.5 1 2 0 0.0069 16 0 0 0 3.39E+08 4.32E+07 - - - 5.256 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.20017.20017.2 0.000534 18-Sep R.VFYYLVQDLK.C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1286.6911 0.93 34104 20017 2 1286.697714 644.3528 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3747.7 - 787310 - - - 5.1597 - 2.126 0.436 - 263.3 1 2 0 0.0066 10 0 0 0 6.32E+07 6.79E+07 - - - 4.3645 1 230117_WJC_METTL3_WT_vs_EV_F04.20019.20019.2 0.000848 24-Dec R.NLANTVTEEILEK[136.11].A "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1480.7864 -1 34106 20019 2 1480.789779 741.4005 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.25 3747.9 - 482146 - - - 2.2556 - 2.606 0.463 - 346.4 1 2 0 0.0033 13 0 0 0 0.00E+00 0.00E+00 - - - 4.9179 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.20020.20020.2 1.57 16-May R.LELPADLLR[166.11].Q "sp|Q96NU1|SAM11_HUMAN,tr|A0A087WYW1|A0A087WYW1_HUMAN,tr|A0A087WX24|A0A087WX24_HUMAN,tr|A0A087X1J5|A0A087X1J5_HUMAN,tr|A0A087X223|A0A087X223_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|A0A087WXB3|A0A087WXB3_HUMAN,tr|H7C3J6|H7C3J6_HUMAN,tr|A0A087WYU3|A0A087WYU3_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 10 1048.6156 3.21 34107 20020 2 1048.617263 525.3151 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3 4.37 3748.1 - 430115 - - - 1.5706 - 1.382 0.214 - 64.3 9 2 0 0.0016 9 0 0 0 5.74E+06 1.79E+06 - - - 1.1308 0.995 230117_WJC_METTL3_WT_vs_EV_F04.20024.20024.2 0.167 16-Jun R.FFLEETLVR.R "sp|Q9NZT2|OGFR_HUMAN,tr|A0A0A0MRN5|A0A0A0MRN5_HUMAN" 2 1152.6179 1.83 34111 20024 2 1152.616486 577.3162 Opioid growth factor receptor OS=Homo sapiens OX=9606 GN=OGFR PE=1 SV=3 4.53 3748.6 - 341900 - - - -1.2354 - 1.378 0.265 - 105 1 2 0 -0.0014 9 0 0 0 1.70E+06 9.26E+05 - - - 1.9255 0.9948 230117_WJC_METTL3_WT_vs_EV_F04.20025.20025.2 0.00379 16-Aug R.VDALLLDLR.Q "sp|O75586|MED6_HUMAN,tr|G3V4A5|G3V4A5_HUMAN,tr|A0A087WYL7|A0A087WYL7_HUMAN" 3 1026.6073 1.49 34112 20025 2 1026.61308 514.3109 Mediator of RNA polymerase II transcription subunit 6 OS=Homo sapiens OX=9606 GN=MED6 PE=1 SV=2 4.21 3748.7 - 294767 - - - 5.5854 - 1.93 0.31 - 185 1 2 0 0.0057 9 0 0 0 2.62E+06 1.75E+06 - - - 3.2311 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20028.20028.2 7.24E-05 18-Sep K.LFQLQTLGLK.G "sp|Q9ULM6|CNOT6_HUMAN,sp|Q96LI5|CNO6L_HUMAN,tr|D6RGK9|D6RGK9_HUMAN,tr|H0Y9C1|H0Y9C1_HUMAN,tr|H0Y9Z5|H0Y9Z5_HUMAN" 5 1159.6965 1.2 34114 20028 2 1159.698704 580.8555 CCR4-NOT transcription complex subunit 6 OS=Homo sapiens OX=9606 GN=CNOT6 PE=1 SV=2 8.75 3749.1 - 65467.2 - - - 1.9048 - 1.932 0.437 - 141.9 1 2 0 0.0022 10 0 0 0 4.74E+06 3.96E+06 - - - 4.1062 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.20030.20030.2 0.754 12-Jul R.WIVNLIR[166.11].N "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 15 922.5628 0.97 34115 20030 2 922.563239 462.2887 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 9.75 3749.3 - 1.04E+07 - - - 0.4845 - 1.21 0.217 - 274.4 1 2 0 0.0004 7 0 0 0 3.20E+07 3.29E+07 - - - 1.2476 1 230117_WJC_METTL3_WT_vs_EV_F04.20031.20031.2 0.00742 18-Oct K.YFSSMAEFLK.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1221.574 1.26 34116 20031 2 1221.575463 611.7943 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 3749.3 - 7.07E+06 - - - 1.2001 - 1.927 0.547 - 218.3 1 2 0 0.0015 10 0 0 0 3.92E+07 3.10E+07 - - - 4.9117 1 230117_WJC_METTL3_WT_vs_EV_F04.20032.20032.3 5.51E-09 16/60 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 5.54 34117 20032 3 1549.884225 517.6349 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3749.4 - 1.19E+07 - - - 0.9246 - 3.033 0.561 - 460.6 1 2 0 0.0014 16 0 0 0 2.14E+07 3.87E+06 - - - 7.6412 1 230117_WJC_METTL3_WT_vs_EV_F04.20033.20033.2 1.44E-06 18-Oct R.VFYYLVQDLK[136.11].C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1294.7053 0.93 34118 20033 2 1294.706695 648.3599 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3749.4 - 7.78E+06 - - - 1.0968 - 2.256 0.523 - 409.6 1 2 0 0.0014 10 0 0 0 6.32E+07 6.79E+07 - - - 5.1744 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20034.20034.2 0.00769 18-Aug R.YVEFNLLYDR.G "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1330.6558 1.21 34119 20034 2 1330.657298 666.3352 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.37 3749.4 - 4.60E+06 - - - 1.1618 - 1.725 0.445 - 218.5 1 2 0 0.0015 10 0 0 0 1.38E+07 1.14E+07 - - - 3.8492 0.9604 230117_WJC_METTL3_WT_vs_EV_F04.20037.20037.3 0.0412 15/60 R.ALIAGGGAPEIELALR[166.11].L sp|P50991|TCPD_HUMAN 1 1559.8911 5.54 34122 20037 3 1559.893357 520.971 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3749.6 - 1.65E+06 - - - 1.4713 - 2.038 0.024 - 211.3 1 2 0 0.0023 16 0 0 0 2.14E+07 3.87E+06 - - - 0.6338 0.999 230117_WJC_METTL3_WT_vs_EV_F04.20039.20039.2 0.000884 14-Sep R.WLLSDYVK.V "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN,tr|C9JZH6|C9JZH6_HUMAN" 3 1022.5437 2.51 34124 20039 2 1022.543724 512.2791 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.83 3749.8 - 1.64E+06 - - - 0.0401 - 1.73 0.293 - 379.8 1 2 0 0 8 0 0 0 7.51E+06 2.99E+06 - - - 2.8582 0.999 230117_WJC_METTL3_WT_vs_EV_F04.20040.20040.2 0.00621 13/26 K.IPPPVIMVQNVSFK.Y sp|Q9UG63|ABCF2_HUMAN 1 1567.8796 3.34 34125 20040 2 1567.87773 784.9471 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.75 3749.8 - 1.14E+06 - - - -1.2061 - 2.179 0.404 - 404.1 1 2 0 -0.0019 14 0 0 0 4.65E+06 1.39E+06 - - - 3.9789 0.999 230117_WJC_METTL3_WT_vs_EV_F04.20042.20042.2 0.000449 20-Oct K.DSLTLVFVETK[136.11].K "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1258.69 0.01 34127 20042 2 1258.693826 630.3523 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3750 - 661099 - - - 3.0246 - 1.703 0.362 - 249.2 1 2 0 0.0038 11 0 0 0 3.40E+04 3.64E+06 - - - 3.1538 0.9948 230117_WJC_METTL3_WT_vs_EV_F04.20044.20044.2 0.0052 12-Jul K.LFFLQVK[136.11].E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 901.5517 0.83 34129 20044 2 901.554871 451.7831 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3750.3 - 566792 - - - 3.545 - 1.526 0.18 - 141.5 1 2 0 0.0032 7 0 0 0 6.90E+06 8.29E+06 - - - 1.7087 0.9821 230117_WJC_METTL3_WT_vs_EV_F04.20046.20046.2 0.353 14-Jul K.LLQPFLLR.R "sp|Q86WJ1|CHD1L_HUMAN,tr|A0A087WTM4|A0A087WTM4_HUMAN,tr|A0A494C0J6|A0A494C0J6_HUMAN,tr|A0A0A0MSH9|A0A0A0MSH9_HUMAN,tr|A0A494C1P7|A0A494C1P7_HUMAN,tr|A0A494C1F7|A0A494C1F7_HUMAN,tr|A0A494C0F0|A0A494C0F0_HUMAN,tr|A0A0A0MRH8|A0A0A0MRH8_HUMAN" 8 998.6277 3.1 34131 20046 2 998.627741 500.3211 Chromodomain-helicase-DNA-binding protein 1-like OS=Homo sapiens OX=9606 GN=CHD1L PE=1 SV=3 9.75 3750.6 - 479533 - - - 0.0541 - 1.301 0.065 - 149.7 1 2 0 0.0001 8 0 0 0 9.54E+05 3.08E+05 - - - 0.3147 0.9923 230117_WJC_METTL3_WT_vs_EV_F04.20048.20048.2 1.25 14-Aug R.LLLEDLVK.K "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 941.5797 1.45 34133 20048 2 941.581426 471.7971 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 4.37 3750.8 - 278922 - - - 1.797 - 1.159 0.163 - 125.4 1 2 0 0.0017 8 0 0 0 2.67E+06 1.85E+06 - - - 0.6894 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.20050.20050.2 0.0394 12-Jul R.WIVNLIR.N "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 15 912.5545 0.97 34134 20050 2 912.555173 457.2845 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 9.75 3751 - 3.93E+06 - - - 0.7134 - 1.398 0.312 - 256.6 1 2 0 0.0007 7 0 0 0 3.20E+07 3.29E+07 - - - 2.4068 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.20051.20051.2 6.42 20-Nov K.TVLELQYVLDK.L "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1319.7337 1.14 34135 20051 2 1319.73445 660.8741 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.37 3751.1 - 804368 - - - 0.5918 - 2.002 0.144 - 309.1 1 2 0 0.0008 11 0 0 0 2.08E+08 1.83E+08 - - - 1.9822 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20055.20055.2 4.20E-05 16-Oct R.LTSFITVFK.Y "sp|Q13617|CUL2_HUMAN,tr|Q5T2B5|Q5T2B5_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 3 1054.6063 3.93 34139 20055 2 1054.60791 528.3104 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 8.75 3751.4 - 919043 - - - 1.5428 - 2.249 0.308 - 287.4 1 2 0 0.0016 9 0 0 0 1.08E+07 2.75E+06 - - - 3.6602 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.20060.20060.2 0.119 12-Jul K.LFFLQVK.E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 893.5375 0.83 34144 20060 2 893.537475 447.776 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3752.1 - 542314 - - - 0 - 1.454 0.184 - 122.9 1 2 0 0 7 0 0 0 6.90E+06 8.29E+06 - - - 1.5861 0.905 230117_WJC_METTL3_WT_vs_EV_F04.20063.20063.2 0.019 20-Aug R.YLLLLAAGDPR.E "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1200.6867 2.85 34147 20063 2 1200.678549 601.3506 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.84 3752.5 - 477613 - - - -6.7545 - 1.778 0.233 - 167.4 1 2 0 -0.0081 11 0 0 0 5.07E+06 1.78E+06 - - - 2.3162 0.999 230117_WJC_METTL3_WT_vs_EV_F04.20065.20065.2 9.27E-05 20-Sep K.LLVYEALEYAK.R "sp|Q96DB5|RMD1_HUMAN,tr|H0YB83|H0YB83_HUMAN,tr|E5RH53|E5RH53_HUMAN,tr|H0YB03|H0YB03_HUMAN" 4 1310.7122 -1 34149 20065 2 1310.716994 656.3634 Regulator of microtubule dynamics protein 1 OS=Homo sapiens OX=9606 GN=RMDN1 PE=1 SV=1 4.53 3752.7 - 256768 - - - 3.6537 - 2.01 0.384 - 248.8 1 2 0 0.0048 11 0 0 0 0.00E+00 0.00E+00 - - - 3.7643 0.993 230117_WJC_METTL3_WT_vs_EV_F04.20069.20069.2 0.116 22-Dec K.LGAIFLEGVTVK.G sp|O60942|MCE1_HUMAN 1 1245.7333 26.16 34151 20069 2 1245.741923 623.8739 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 6 3753.2 - 5.29E+06 - - - 6.9421 - 2.329 0.411 - 472.9 1 2 0 0.0086 12 0 0 0 1.40E+07 5.34E+05 - - - 4.2984 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.20070.20070.2 6.77E-05 16-Sep R.NSYLEVLLK.L sp|Q15084|PDIA6_HUMAN 1 1077.607 1.35 34152 20070 2 1077.611112 539.8108 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 6 3753.3 - 2.53E+06 - - - 3.8057 - 2.001 0.417 - 281.1 1 2 0 0.0041 9 0 0 0 6.73E+06 4.98E+06 - - - 4.1264 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.20071.20071.2 0.0105 16-Oct R.IQEFIELIR.Q "sp|Q7L5Y9|MAEA_HUMAN,tr|B4DVN3|B4DVN3_HUMAN,tr|B4DQT1|B4DQT1_HUMAN,tr|E7ESC7|E7ESC7_HUMAN,tr|D6RE80|D6RE80_HUMAN" 5 1159.6601 -1 34153 20071 2 1159.664769 580.8373 E3 ubiquitin-protein transferase MAEA OS=Homo sapiens OX=9606 GN=MAEA PE=1 SV=1 4.53 3753.4 - 2.34E+06 - - - 4.0176 - 2.215 0.313 - 321.2 1 2 0 0.0047 9 0 0 0 0.00E+00 0.00E+00 - - - 3.6521 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.20073.20073.2 0.0407 14-Jul K.AIFLFVDK.T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 951.543 1.23 34155 20073 2 951.54573 476.7788 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3753.7 - 2.11E+06 - - - 2.9174 - 1.371 0.398 - 157.8 1 2 0 0.0028 8 0 0 0 6.17E+06 5.03E+06 - - - 2.9314 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20074.20074.2 0.00121 22-Nov K.ALFSLAPEVEVR.V "sp|Q8N3Z3|GTPB8_HUMAN,tr|C9J8V5|C9J8V5_HUMAN,tr|F8WBY6|F8WBY6_HUMAN" 3 1329.7293 1.28 34156 20074 2 1329.733643 665.8719 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.53 3753.8 - 2.03E+06 - - - 3.3022 - 2.25 0.372 - 443.8 1 2 0 0.0044 12 0 0 0 6.04E+06 4.70E+06 - - - 3.9209 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.20075.20075.2 0.003 14-Aug K.AIFLFVDK[136.11].T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 959.5572 1.23 34157 20075 2 959.560077 480.7859 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3753.9 - 1.89E+06 - - - 3.0462 - 1.646 0.336 - 245.4 1 2 0 0.0029 8 0 0 0 6.17E+06 5.03E+06 - - - 3.0248 0.992 230117_WJC_METTL3_WT_vs_EV_F04.20079.20079.2 0.00718 16-Aug R.LTSFITVFK[136.11].Y "sp|Q13617|CUL2_HUMAN,tr|Q5T2B5|Q5T2B5_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 3 1062.6205 3.91 34161 20079 2 1062.626043 532.3175 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 8.75 3754.4 - 1.37E+06 - - - 5.2323 - 1.874 0.209 - 132.9 1 2 0 0.0056 9 0 0 0 1.07E+07 2.75E+06 - - - 2.4 0.9875 230117_WJC_METTL3_WT_vs_EV_F04.20080.20080.3 0.0633 Nov-40 R.AALLELWELR[166.11]R[166.11].Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1388.8043 0.69 34162 20080 3 1388.806127 463.942 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.19 3754.5 - 1.21E+06 - - - 1.3083 - 1.947 0.084 - 230.3 1 2 0 0.0018 11 0 0 0 3.72E+06 5.37E+06 - - - 1.3688 0.9069 230117_WJC_METTL3_WT_vs_EV_F04.20083.20083.2 0.0246 16-Aug K.INMLVIELK.S "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1071.6362 -1 34165 20083 2 1071.645483 536.8254 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3754.9 - 820035 - - - 8.6597 - 1.597 0.182 - 110.8 1 2 0 0.0093 9 0 0 0 0.00E+00 0.00E+00 - - - 1.7367 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.20090.20090.2 0.297 16-Oct R.LELPADLLR.Q "sp|Q96NU1|SAM11_HUMAN,tr|A0A087WYW1|A0A087WYW1_HUMAN,tr|A0A087WX24|A0A087WX24_HUMAN,tr|A0A087X1J5|A0A087X1J5_HUMAN,tr|A0A087X223|A0A087X223_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|A0A087WXB3|A0A087WXB3_HUMAN,tr|H7C3J6|H7C3J6_HUMAN,tr|A0A087WYU3|A0A087WYU3_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 10 1038.6073 3.7 34171 20090 2 1038.611587 520.3109 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3 4.37 3755.9 - 861641 - - - 4.0834 - 1.969 0.297 - 330 1 2 0 0.0042 9 0 0 0 7.00E+06 1.89E+06 - - - 3.1934 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.20091.20091.2 0.00506 18-Nov R.DLASVQALLR.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1084.6241 0.55 34172 20091 2 1084.630281 543.3193 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3756 - 3.00E+06 - - - 5.7375 - 2.327 0.357 - 422.6 1 2 0 0.0062 10 0 0 0 9.90E+06 1.80E+07 - - - 4.0333 1 230117_WJC_METTL3_WT_vs_EV_F04.20092.20092.2 0.00136 14/18 R.LTTLELLEVR[166.11].R "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1195.7052 0.79 34173 20092 2 1195.710519 598.8599 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.53 3756 - 2.73E+06 - - - 4.4827 - 2.574 0.449 - 798.8 1 2 0 0.0054 10 0 0 0 1.49E+07 1.88E+07 - - - 4.9947 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.20093.20093.2 0.0128 14/22 R.ALLANALTSALR[166.11].L "sp|P57088|TMM33_HUMAN,tr|D6RAA6|D6RAA6_HUMAN" 2 1222.7273 -1 34174 20093 2 1222.732488 612.3709 Transmembrane protein 33 OS=Homo sapiens OX=9606 GN=TMEM33 PE=1 SV=2 9.79 3756.2 - 1.50E+06 - - - 4.2503 - 2.376 0.326 - 956 1 2 0 0.0052 12 0 0 0 0.00E+00 0.00E+00 - - - 3.7243 1 230117_WJC_METTL3_WT_vs_EV_F04.20094.20094.2 0.021 18-Dec R.FC[160.03]IWTESAFR[166.11].K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1325.6102 1.24 34175 20094 2 1325.614638 663.8124 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3756.3 - 1.35E+06 - - - 3.3381 - 2.391 0.422 - 656 1 2 0 0.0044 10 0 0 0 7.36E+06 5.95E+06 - - - 4.5897 0.9891 230117_WJC_METTL3_WT_vs_EV_F04.20098.20098.2 3.44 12-Aug R.TLLEFLK.R "sp|Q14232|EI2BA_HUMAN,tr|F5H0D0|F5H0D0_HUMAN,tr|H0YGG4|H0YGG4_HUMAN" 3 862.5164 0.94 34179 20098 2 862.520448 432.2655 Translation initiation factor eIF-2B subunit alpha OS=Homo sapiens OX=9606 GN=EIF2B1 PE=1 SV=1 5.66 3756.7 - 1.01E+06 - - - 4.6874 - 1.446 0.208 - 211.9 1 2 0 0.004 7 0 0 0 5.18E+06 5.51E+06 - - - 1.7446 1 230117_WJC_METTL3_WT_vs_EV_F04.20099.20099.2 0.00294 18-Nov R.FC[160.03]IWTESAFR.K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1315.6019 -1 34180 20099 2 1315.607894 658.8082 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3756.9 - 906221 - - - 4.5234 - 2.263 0.447 - 550.7 1 2 0 0.006 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6203 1 230117_WJC_METTL3_WT_vs_EV_F04.20102.20102.2 2.46E-06 22-Oct K.FLQDTIEEMALK[136.11].N sp|O95202|LETM1_HUMAN 1 1444.7363 6.23 34183 20102 2 1444.742982 723.3754 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.14 3757.3 - 709615 - - - 4.6126 - 2.365 0.461 - 239.3 1 2 0 0.0067 12 0 0 0 1.43E+07 2.30E+06 - - - 4.7087 1 230117_WJC_METTL3_WT_vs_EV_F04.20104.20104.2 2.33E-07 14/28 L.LVSVSALTLATETVR.S sp|P50991|TCPD_HUMAN 1 1558.893 111.77 34185 20104 2 1558.898701 780.4538 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6 3757.5 - 678214 - - - 3.6423 - 2.735 0.577 - 690.5 1 1 0 0.0057 15 0 0 0 3.13E+07 2.80E+05 - - - 5.7746 1 230117_WJC_METTL3_WT_vs_EV_F04.20105.20105.2 0.00034 14/20 R.AFITNIPFDVK[136.11].W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1271.7005 2.57 34186 20105 2 1271.705847 636.8575 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3757.6 - 601027 - - - 4.1857 - 2.302 0.494 - 746.5 1 2 0 0.0053 11 0 0 0 3.21E+08 1.25E+08 - - - 4.9436 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.20110.20110.2 0.017 18-Oct R.DLASVQALLR[166.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1094.6323 0.68 34190 20110 2 1094.637755 548.3234 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3758.2 - 588531 - - - 4.9578 - 2.132 0.329 - 330.2 1 2 0 0.0054 10 0 0 0 9.90E+06 1.46E+07 - - - 3.5825 1 230117_WJC_METTL3_WT_vs_EV_F04.20111.20111.2 0.00119 13/20 R.AFITNIPFDVK.W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1263.6863 2.53 34191 20111 2 1263.692121 632.8504 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3758.3 - 1.65E+06 - - - 4.5874 - 2.204 0.462 - 634.3 1 2 0 0.0058 11 0 0 0 3.21E+08 1.27E+08 - - - 4.5894 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.20115.20115.2 0.026 14-Jul K.EILIPVFK.N sp|P53396|ACLY_HUMAN 1 957.5899 1.32 34195 20115 2 957.592264 479.8022 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3758.6 - 383462 - - - 2.4635 - 1.458 0.28 - 169 1 2 0 0.0024 8 0 0 0 2.79E+07 2.11E+07 - - - 2.2456 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.20116.20116.2 0.0163 14-Jul K.EILIPVFK[136.11].N sp|P53396|ACLY_HUMAN 1 965.6041 1.32 34196 20116 2 965.605818 483.8093 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3758.7 - 359952 - - - 1.774 - 1.438 0.384 - 169 1 2 0 0.0017 8 0 0 0 2.79E+07 2.11E+07 - - - 2.9722 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.20117.20117.2 0.0187 14-Jul K.QDILTIFK[136.11].R "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV8|B0QYV8_HUMAN" 2 984.5735 1.81 34197 20117 2 984.57715 493.294 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3758.8 - 345239 - - - 3.6737 - 1.7 0.337 - 153.9 1 2 0 0.0036 8 0 0 0 1.36E+07 7.49E+06 - - - 3.1293 1 230117_WJC_METTL3_WT_vs_EV_F04.20119.20119.2 9.99E-06 16/26 K.LLTGELLPTDGMIR.K sp|Q9UG63|ABCF2_HUMAN 1 1527.8331 2.01 34199 20119 2 1527.84014 764.9238 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.37 3759 - 256412 - - - 4.6307 - 2.875 0.452 - 696.8 1 2 0 0.0071 14 0 0 0 7.97E+06 3.96E+06 - - - 5.0274 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.20122.20122.2 0.0337 12-Aug R.YGLVFFR.Q "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN,tr|F6WRY4|F6WRY4_HUMAN" 4 900.4858 1.24 34202 20122 2 900.488102 451.2502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.75 3759.4 - 194325 - - - 2.5853 - 1.711 0.245 - 255.5 1 2 0 0.0023 7 0 0 0 4.17E+06 3.37E+06 - - - 2.5516 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.20125.20125.2 0.869 18-Nov K.LGLFPSNFVK.E sp|Q9Y5K6|CD2AP_HUMAN 1 1120.6281 1.71 34205 20125 2 1120.631119 561.3213 CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1 8.75 3759.8 - 132871 - - - 2.711 - 2.046 0.268 - 281.3 1 2 0 0.003 10 0 0 0 4.50E+06 2.63E+06 - - - 3.0178 1 230117_WJC_METTL3_WT_vs_EV_F04.20127.20127.2 0.00174 16/26 K.ALLAVIGADSVTLK.N sp|Q9NYH9|UTP6_HUMAN 1 1369.8181 1.47 34207 20127 2 1369.820558 685.9163 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3760 - 107140 - - - 1.8185 - 3.034 0.388 - 1084.1 1 2 0 0.0025 14 0 0 0 2.75E+06 1.87E+06 - - - 4.6912 1 230117_WJC_METTL3_WT_vs_EV_F04.20129.20129.2 5.76E-07 20-Nov R.FSYLAVIEGAK[136.11].F "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 1204.6583 1.72 34209 20129 2 1204.659952 603.3364 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 6 3760.3 - 102500 - - - 1.3506 - 2.093 0.563 - 321 1 2 0 0.0016 11 0 0 0 6.34E+06 3.68E+06 - - - 5.1969 0.9676 230117_WJC_METTL3_WT_vs_EV_F04.20131.20131.2 4.8 12-May R.TLLEFLK[136.11].R "sp|Q14232|EI2BA_HUMAN,tr|F5H0D0|F5H0D0_HUMAN,tr|H0YGG4|H0YGG4_HUMAN" 3 870.5306 1.66 34210 20131 2 870.532356 436.2726 Translation initiation factor eIF-2B subunit alpha OS=Homo sapiens OX=9606 GN=EIF2B1 PE=1 SV=1 5.66 3760.6 - 318373 - - - 2.0114 - 1.174 0.046 - 95.5 2 2 0 0.0018 7 0 0 0 3.15E+06 1.90E+06 - - - -0.246 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.20133.20133.2 0.000228 20-Oct R.ELGLGLGLGLK.E "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 1068.6543 1.1 34212 20133 2 1068.657454 535.3344 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 6.1 3760.7 - 465926 - - - 2.9551 - 1.738 0.45 - 251.9 1 2 0 0.0032 11 0 0 0 6.85E+06 6.24E+06 - - - 3.859 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20134.20134.2 0.000229 20-Nov R.ELGLGLGLGLK[136.11].E "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 1076.6685 1.1 34213 20134 2 1076.670327 539.3415 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 6.1 3760.8 - 441287 - - - 1.7006 - 1.991 0.478 - 312 1 2 0 0.0018 11 0 0 0 6.85E+06 6.24E+06 - - - 4.4339 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20136.20136.2 0.000293 12-Aug R.YGLVFFR[166.11].Q "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN,tr|F6WRY4|F6WRY4_HUMAN" 4 910.494 1.26 34215 20136 2 910.495095 456.2543 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.75 3761 - 313141 - - - 1.1543 - 1.665 0.361 - 281.9 1 2 0 0.0011 7 0 0 0 4.23E+06 3.37E+06 - - - 3.3224 0.9896 230117_WJC_METTL3_WT_vs_EV_F04.20140.20140.2 0.0527 12-Jul R.WFVFDAR.R sp|Q9UPU7|TBD2B_HUMAN 1 939.4603 1.19 34219 20140 2 939.464757 470.7374 TBC1 domain family member 2B OS=Homo sapiens OX=9606 GN=TBC1D2B PE=1 SV=2 5.84 3761.4 - 156549 - - - 4.7581 - 1.335 0.254 - 127.8 1 2 0 0.0045 7 0 0 0 9.08E+05 7.65E+05 - - - 1.8311 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20146.20146.2 0.000101 16-Aug R.DGFVC[160.03]ALLR.F "sp|Q8WUY1|THEM6_HUMAN,tr|H0YAR9|H0YAR9_HUMAN" 2 1049.5328 1.26 34223 20146 2 1049.532101 525.7737 Protein THEM6 OS=Homo sapiens OX=9606 GN=THEM6 PE=1 SV=2 5.83 3762.1 - 1.72E+06 - - - -0.667 - 1.692 0.479 - 204.9 1 2 0 -0.0007 9 0 0 0 3.26E+06 2.58E+06 - - - 4.1002 1 230117_WJC_METTL3_WT_vs_EV_F04.20147.20147.2 0.000993 24-Nov K.ILTFDQLALDSPK[136.11].G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1467.8064 0.81 34224 20147 2 1467.805621 734.9105 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3762.2 - 1.69E+06 - - - -0.5621 - 2.555 0.509 - 358.4 1 2 0 -0.0008 13 0 0 0 6.34E+07 7.79E+07 - - - 5.2078 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.20149.20149.2 0.00403 16-Aug R.ALQLLYDLR.Y "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1103.6339 1.1 34226 20149 2 1103.636777 552.8242 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.88 3762.3 - 1.64E+06 - - - 2.6114 - 1.854 0.29 - 251.7 1 2 0 0.0029 9 0 0 0 4.03E+06 3.67E+06 - - - 2.968 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.20150.20150.3 2.81E-05 Oct-44 R.LLHLPLSLTALK.L sp|Q9BTT6|LRRC1_HUMAN 1 1317.8384 3.74 34227 20150 3 1317.838817 440.2867 Leucine-rich repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRRC1 PE=1 SV=1 8.76 3762.4 - 1.49E+06 - - - 0.3104 - 2.354 0.447 - 176.6 1 2 0 0.0004 12 0 0 0 2.65E+06 7.07E+05 - - - 5.8965 1 230117_WJC_METTL3_WT_vs_EV_F04.20151.20151.2 3.73E-05 14/24 K.ILTFDQLALDSPK.G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1459.7922 0.81 34228 20151 2 1459.792986 730.9034 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3762.5 - 1.26E+06 - - - 0.5069 - 2.832 0.525 - 727.1 1 2 0 0.0007 13 0 0 0 6.34E+07 7.79E+07 - - - 5.5901 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.20152.20152.2 0.143 12-Jun R.DVFLMLK[136.11].K "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 872.4921 0.91 34229 20152 2 872.493063 437.2533 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 5.84 3762.6 - 1.20E+06 - - - 1.0911 - 1.262 0.27 - 142.4 1 2 0 0.001 7 0 0 0 2.19E+06 2.41E+06 - - - 1.7722 1 230117_WJC_METTL3_WT_vs_EV_F04.20160.20160.2 7.74E-07 13/22 K.MFIGGLSWDTTK[136.11].K "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 1362.6733 1.07 34237 20160 2 1362.672669 682.3439 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 5.59 3763.5 - 707854 - - - -0.4799 - 2.292 0.583 - 432.8 1 2 0 -0.0007 12 0 0 0 8.61E+06 8.05E+06 - - - 5.5292 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20162.20162.2 0.0553 26-Nov K.ALLAVIGADSVTLK[136.11].N sp|Q9NYH9|UTP6_HUMAN 1 1377.8323 1.47 34239 20162 2 1377.833509 689.9234 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3763.8 - 640376 - - - 0.9014 - 2.536 0.344 - 402.9 1 2 0 0.0012 14 0 0 0 2.75E+06 1.87E+06 - - - 3.9167 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.20164.20164.2 0.0352 20-Jul R.NFLSTPQFLYR.W "sp|Q9BUN8|DERL1_HUMAN,tr|E5RGY0|E5RGY0_HUMAN,tr|B4E1G1|B4E1G1_HUMAN" 3 1384.7139 -1 34240 20164 2 1384.715087 693.3642 Derlin-1 OS=Homo sapiens OX=9606 GN=DERL1 PE=1 SV=1 8.75 3764 - 109927 - - - 0.8312 - 1.446 0.299 - 162.8 1 2 0 0.0012 11 0 0 0 0.00E+00 0.00E+00 - - - 2.2467 0.9874 230117_WJC_METTL3_WT_vs_EV_F04.20166.20166.2 1.69 14-Jul R.LLLTPWVK[136.11].F sp|Q14152|EIF3A_HUMAN 1 976.6201 0.88 34242 20166 2 976.622785 489.3173 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.75 3764.3 - 1.97E+06 - - - 2.7605 - 1.469 0.059 - 110.3 1 2 0 0.0027 8 0 0 0 8.49E+06 9.70E+06 - - - 0.6358 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.20167.20167.2 0.00911 20-Dec R.VLPSIVNEVLK.S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1209.7333 1.27 34243 20167 2 1209.739236 605.8739 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3764.4 - 1.87E+06 - - - 4.9275 - 1.827 0.434 - 395.2 1 2 0 0.006 11 0 0 0 5.17E+06 4.06E+06 - - - 3.875 1 230117_WJC_METTL3_WT_vs_EV_F04.20168.20168.2 9.06E-08 13/22 R.LFTNFSGADLLK.L "sp|Q12800|TFCP2_HUMAN,tr|F8VWL0|F8VWL0_HUMAN" 2 1324.7027 1.66 34244 20168 2 1324.705299 663.3586 Alpha-globin transcription factor CP2 OS=Homo sapiens OX=9606 GN=TFCP2 PE=1 SV=2 5.84 3764.6 - 920954 - - - 1.9597 - 2.815 0.586 - 509.6 1 2 0 0.0026 12 0 0 0 4.89E+06 2.95E+06 - - - 6.0915 0.8988 230117_WJC_METTL3_WT_vs_EV_F04.20170.20170.2 0.44 20-Sep R.LLTGWMPTAIR.G "sp|Q12769|NU160_HUMAN,tr|E9PR16|E9PR16_HUMAN,tr|G3V198|G3V198_HUMAN" 3 1257.6904 -1 34246 20170 2 1257.701154 629.8525 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 9.75 3764.8 - 757335 - - - 8.5792 - 1.443 0.218 - 234.6 1 2 0 0.0108 11 0 0 0 0.00E+00 0.00E+00 - - - 1.6398 0.8603 230117_WJC_METTL3_WT_vs_EV_F04.20171.20171.2 0.0016 16-Aug R.LFPLIQTMH.S "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 9 1098.5896 - 34247 20171 2 1098.593875 550.3021 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.74 3764.9 - 467326 - - - 3.9032 - 1.529 0.361 - 212.2 1 1 0 0.0043 9 0 0 0 - - - - - 2.9344 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20172.20172.3 0.00167 Oct-40 K.LLPQFLLHLDK.L "sp|Q8N4J0|CARME_HUMAN,tr|Q5T8V1|Q5T8V1_HUMAN,tr|Q5T8U9|Q5T8U9_HUMAN" 3 1335.7915 1.67 34248 20172 3 1335.795991 446.2711 Carnosine N-methyltransferase OS=Homo sapiens OX=9606 GN=CARNMT1 PE=1 SV=1 6.74 3765.1 - 444423 - - - 3.3935 - 1.853 0.415 - 87.2 1 2 0 0.0045 11 0 0 0 1.50E+06 9.00E+05 - - - 4.9178 0.9829 230117_WJC_METTL3_WT_vs_EV_F04.20176.20176.2 13.9 22-Jul K.SFSTALYGESDL.- "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|H0YJW3|H0YJW3_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|H7C144|H7C144_HUMAN" 14 1288.5823 - 34252 20176 2 1288.583901 645.2984 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 3.67 3765.6 - 235331 - - - 1.2324 - 1.168 0.089 - 89.7 1 2 0 0.0016 12 0 0 0 - - - - - 0.1065 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20189.20189.2 0.00917 16-Sep K.LGFMSAFVK[136.11].A "sp|P36957|ODO2_HUMAN,tr|Q86SW4|Q86SW4_HUMAN" 2 1006.5401 0.98 34264 20189 2 1006.541978 504.2773 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 8.75 3767.3 - 841462 - - - 1.842 - 1.797 0.351 - 189.6 1 2 0 0.0019 9 0 0 0 2.77E+06 2.84E+06 - - - 3.3286 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20190.20190.2 0.00589 14-Jul R.DWVLNEFR[166.11].S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1087.5326 1.32 34265 20190 2 1087.533406 544.7736 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3767.4 - 821098 - - - 0.7283 - 1.704 0.294 - 295.9 1 2 0 0.0008 8 0 0 0 2.59E+07 1.97E+07 - - - 2.8197 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20192.20192.2 5.04E-06 16-Sep K.MTILQTYFR.Q sp|O75348|VATG1_HUMAN 1 1171.606 0.34 34267 20192 2 1171.608637 586.8103 V-type proton ATPase subunit G 1 OS=Homo sapiens OX=9606 GN=ATP6V1G1 PE=1 SV=3 8.5 3767.5 - 640990 - - - 2.2806 - 1.954 0.348 - 345.8 1 2 0 0.0027 9 0 0 0 2.14E+06 6.28E+06 - - - 3.5485 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20193.20193.2 0.00228 20-Oct R.VLPSIVNEVLK[136.11].S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1217.7475 1.43 34268 20193 2 1217.749067 609.881 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3767.6 - 580684 - - - 1.3073 - 2.196 0.449 - 409 1 2 0 0.0016 11 0 0 0 1.87E+08 1.31E+08 - - - 4.4849 1 230117_WJC_METTL3_WT_vs_EV_F04.20198.20198.2 3.99E-07 13/28 K.ELVGPPLAETVFTPK.T sp|P49792|RBP2_HUMAN 1 1596.8763 2.27 34273 20198 2 1596.87691 799.4454 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3768.1 - 369921 - - - 0.3757 - 2.302 0.54 - 451.8 1 2 0 0.0006 15 0 0 0 1.50E+07 6.63E+06 - - - 5.0791 1 230117_WJC_METTL3_WT_vs_EV_F04.20199.20199.2 0.0031 17/20 R.IPDQLVILDMK.H "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1283.7159 1.44 34274 20199 2 1283.717726 642.8652 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.21 3768.2 - 353394 - - - 1.4146 - 3.253 0.497 - 1456.9 1 2 0 0.0018 11 0 0 0 5.07E+07 3.52E+07 - - - 5.9023 1 230117_WJC_METTL3_WT_vs_EV_F04.20202.20202.2 6.08E-07 28-Nov K.ELVGPPLAETVFTPK[136.11].T sp|P49792|RBP2_HUMAN 1 1604.8905 2.27 34277 20202 2 1604.891289 803.4525 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3768.6 - 231207 - - - 0.4854 - 1.941 0.547 - 235.7 1 2 0 0.0008 15 0 0 0 1.50E+07 6.63E+06 - - - 4.7114 1 230117_WJC_METTL3_WT_vs_EV_F04.20209.20209.2 0.000123 16/20 R.IPDQLVILDMK[136.11].H "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1291.7301 1.44 34283 20209 2 1291.73176 646.8723 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.21 3769.5 - 2.19E+06 - - - 1.2774 - 3.164 0.507 - 1319.2 1 2 0 0.0016 11 0 0 0 5.07E+07 3.52E+07 - - - 5.9012 0.9917 230117_WJC_METTL3_WT_vs_EV_F04.20211.20211.2 0.0676 12-Aug R.FVFLLDR.G sp|Q13045|FLII_HUMAN 1 908.512 1.71 34285 20211 2 908.514713 455.2633 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3769.7 - 1.13E+06 - - - 2.9983 - 1.587 0.074 - 256.7 1 2 0 0.0027 7 0 0 0 1.10E+07 6.45E+06 - - - 1.0501 0.9936 230117_WJC_METTL3_WT_vs_EV_F04.20214.20214.2 0.0119 12-Aug R.FVFLLDR[166.11].G sp|Q13045|FLII_HUMAN 1 918.5203 1.73 34288 20214 2 918.522682 460.2674 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3770.1 - 723671 - - - 2.6379 - 1.488 0.106 - 248.4 1 2 0 0.0024 7 0 0 0 1.12E+07 6.47E+06 - - - 1.0824 0.9922 230117_WJC_METTL3_WT_vs_EV_F04.20215.20215.2 0.822 14-Aug R.LLLTPWVK.F sp|Q14152|EIF3A_HUMAN 1 968.6059 0.88 34289 20215 2 968.60996 485.3102 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.75 3770.3 - 696933 - - - 4.2029 - 1.399 0.23 - 157.5 1 2 0 0.0041 8 0 0 0 8.49E+06 9.70E+06 - - - 1.7511 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.20216.20216.2 0.00498 24-Dec R.LAALPNVYEVISK.S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1415.8024 2.86 34290 20216 2 1415.806562 708.9085 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3770.4 - 668041 - - - 2.9277 - 2.203 0.241 - 356.4 1 2 0 0.0041 13 0 0 0 1.62E+07 5.65E+06 - - - 2.8468 0.9947 230117_WJC_METTL3_WT_vs_EV_F04.20222.20222.3 0.109 14/48 R.WLPLGLGLNHLGK.G "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1416.8242 1.55 34296 20222 3 1416.829468 473.282 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 8.76 3771.2 - 392128 - - - 3.7499 - 2.221 0.176 - 211.4 1 2 0 0.0053 13 0 0 0 3.87E+06 2.49E+06 - - - 2.6643 1 230117_WJC_METTL3_WT_vs_EV_F04.20224.20224.2 8.64E-09 13/36 R.YEGILYTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2100.0627 1.85 34298 20224 2 2100.068674 1051.0386 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3771.4 - 337776 - - - 2.8604 - 2.909 0.589 - 321.4 1 2 0 0.006 19 0 0 0 3.14E+06 1.70E+06 - - - 6.0147 1 230117_WJC_METTL3_WT_vs_EV_F04.20227.20227.2 1.27E-11 15/36 R.YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2108.0769 -1 34300 20227 2 2108.080337 1055.0457 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3771.9 - 765935 - - - 1.6461 - 2.985 0.705 - 559.1 1 2 0 0.0035 19 0 0 0 0.00E+00 0.00E+00 - - - 6.9357 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20229.20229.2 0.000604 18-Oct K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.66 34302 20229 2 1168.708085 585.3606 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3772.1 - 9.20E+06 - - - 1.1637 - 2.113 0.403 - 263.3 1 2 0 0.0014 10 0 0 0 6.15E+09 3.71E+09 - - - 4.1053 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20230.20230.2 0.0101 18-Nov K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.66 34303 20230 2 1176.722 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3772.1 - 8.11E+06 - - - 0.9136 - 2.232 0.351 - 330.2 1 2 0 0.0011 10 0 0 0 6.15E+09 3.71E+09 - - - 3.8743 1 230117_WJC_METTL3_WT_vs_EV_F04.20232.20232.2 7.06E-06 14/26 K.LLAESVTEVEIFGK.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1533.829 1.17 34305 20232 2 1533.831391 767.9218 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 3772.2 - 2.71E+06 - - - 1.5419 - 2.95 0.526 - 595.4 1 2 0 0.0024 14 0 0 0 1.42E+07 1.21E+07 - - - 5.64 1 230117_WJC_METTL3_WT_vs_EV_F04.20233.20233.2 3.63E-07 14/26 K.LLAESVTEVEIFGK[136.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1541.8432 1.17 34306 20233 2 1541.844886 771.9289 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 3772.3 - 2.40E+06 - - - 1.0766 - 2.853 0.557 - 581.3 1 2 0 0.0017 14 0 0 0 1.42E+07 1.21E+07 - - - 5.7853 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20234.20234.2 0.00966 14-Jul R.LFSWLVNR.L "sp|O43795|MYO1B_HUMAN,sp|Q8WXR4|MYO3B_HUMAN,tr|F5H2J1|F5H2J1_HUMAN,tr|A0A0U1RRI3|A0A0U1RRI3_HUMAN,tr|E9PDF6|E9PDF6_HUMAN" 5 1033.5709 1.41 34307 20234 2 1033.571758 517.7927 Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3 9.75 3772.4 - 2.07E+06 - - - 0.8292 - 1.646 0.316 - 167.2 1 2 0 0.0009 8 0 0 0 4.24E+06 3.00E+06 - - - 2.8777 0.995 230117_WJC_METTL3_WT_vs_EV_F04.20236.20236.2 0.0713 12-Jul K.YLFTLIR.A sp|P57740|NU107_HUMAN 1 924.5433 0.3 34309 20236 2 924.544688 463.2789 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 8.75 3772.5 - 1.64E+06 - - - 1.5132 - 1.306 0.147 - 180.2 1 2 0 0.0014 7 0 0 0 6.38E+06 2.11E+07 - - - 0.9722 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.20238.20238.2 0.00092 16-Aug R.DSVVLSLLK[136.11].Q sp|O43264|ZW10_HUMAN 1 980.5997 1.08 34311 20238 2 980.600701 491.3072 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 5.84 3772.6 - 1.42E+06 - - - 0.9719 - 1.644 0.208 - 190.1 1 2 0 0.001 9 0 0 0 4.20E+06 3.87E+06 - - - 2.0152 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20241.20241.2 0.00235 13/24 R.LAALPNVYEVISK[136.11].S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1423.8166 2.85 34314 20241 2 1423.81778 712.9156 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3772.9 - 1.29E+06 - - - 0.8168 - 2.342 0.426 - 476.8 1 2 0 0.0012 13 0 0 0 1.61E+07 5.65E+06 - - - 4.3712 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20242.20242.2 0.000579 16-Sep K.QVDLIDLVR.W sp|Q9UKN8|TF3C4_HUMAN 1 1069.6132 1.33 34315 20242 2 1069.613538 535.8139 General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2 4.21 3773 - 1.17E+06 - - - 0.3543 - 1.895 0.418 - 287.1 1 2 0 0.0004 9 0 0 0 6.75E+06 5.07E+06 - - - 3.9775 0.9966 230117_WJC_METTL3_WT_vs_EV_F04.20243.20243.2 0.0685 14-Jun R.LFSWLVNR[166.11].L "sp|O43795|MYO1B_HUMAN,sp|Q8WXR4|MYO3B_HUMAN,tr|F5H2J1|F5H2J1_HUMAN,tr|A0A0U1RRI3|A0A0U1RRI3_HUMAN,tr|E9PDF6|E9PDF6_HUMAN" 5 1043.5792 1.41 34316 20243 2 1043.578218 522.7969 Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3 9.75 3773.1 - 1.14E+06 - - - -0.9132 - 1.344 0.293 - 109.5 1 2 0 -0.001 8 0 0 0 4.24E+06 3.00E+06 - - - 2.0965 1 230117_WJC_METTL3_WT_vs_EV_F04.20246.20246.2 3.03E-07 22-Dec R.NVYPEEMIVALR.E sp|Q5VT52|RPRD2_HUMAN 1 1432.7384 2.93 34319 20246 2 1432.741188 717.3765 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3773.4 - 847990 - - - 1.9208 - 2.49 0.556 - 488.2 1 2 0 0.0028 12 0 0 0 5.19E+06 1.77E+06 - - - 5.5471 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20248.20248.2 0.0012 18-Aug K.NGFLLDGFPR.T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1134.5822 1.68 34320 20248 2 1134.583861 568.2984 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3773.6 - 770808 - - - 1.4693 - 1.607 0.395 - 202.4 1 2 0 0.0017 10 0 0 0 6.36E+06 3.78E+06 - - - 3.2821 1 230117_WJC_METTL3_WT_vs_EV_F04.20249.20249.2 3.63E-06 17/24 R.LPSDVVTGYLALR.K "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1402.782 1.97 34321 20249 2 1402.784875 702.3983 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 5.84 3773.7 - 1.13E+06 - - - 2.0381 - 2.871 0.556 - 1306.5 1 2 0 0.0029 13 0 0 0 9.83E+06 5.00E+06 - - - 5.8535 1 230117_WJC_METTL3_WT_vs_EV_F04.20250.20250.2 2.15E-05 18-Nov R.TLVEDLFADK.H "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1149.5918 1.33 34322 20250 2 1149.593975 575.8032 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.03 3773.8 - 1.49E+06 - - - 1.9311 - 1.966 0.55 - 353.4 1 2 0 0.0022 10 0 0 0 2.30E+07 1.73E+07 - - - 4.9895 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20253.20253.2 0.00173 18-Oct R.VDILDPALLR.S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1123.6601 2.04 34325 20253 2 1123.662252 562.8373 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3774.1 - 1.11E+06 - - - 1.9063 - 2.271 0.357 - 309.5 1 2 0 0.0021 10 0 0 0 1.80E+08 8.84E+07 - - - 3.9666 0.9723 230117_WJC_METTL3_WT_vs_EV_F04.20254.20254.2 0.0228 16-Dec L.PSIVNEVLK.S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 997.5808 2.3 34326 20254 2 997.582132 499.7977 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 6.43 3774.2 - 870073 - - - 1.3382 - 2.378 0.298 - 386.9 1 1 0 0.0013 9 0 0 0 4.76E+06 2.07E+06 - - - 3.7477 0.9948 230117_WJC_METTL3_WT_vs_EV_F04.20256.20256.3 1.09 Jul-36 K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.79 34328 20256 3 1168.708119 390.5762 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3774.5 - 547215 - - - 1.1928 - 1.629 0.178 - 54.7 1 2 0 0.0014 10 0 0 0 2.46E+07 1.38E+07 - - - 1.9492 1 230117_WJC_METTL3_WT_vs_EV_F04.20258.20258.2 3.15E-05 22-Oct R.DLAQDEAVWLER[166.11].G "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1453.7077 -1 34330 20258 2 1453.710756 727.8611 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 3.92 3774.7 - 418177 - - - 2.1173 - 2.279 0.484 - 302.6 1 2 0 0.0031 12 0 0 0 0.00E+00 0.00E+00 - - - 4.7822 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20267.20267.2 0.982 18-Dec R.VDILDPALLR[166.11].S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1133.6684 2.04 34337 20267 2 1133.670456 567.8415 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3775.9 - 1.29E+06 - - - 1.8312 - 2.233 0.291 - 442.5 1 2 0 0.0021 10 0 0 0 1.80E+08 8.84E+07 - - - 3.4321 1 230117_WJC_METTL3_WT_vs_EV_F04.20268.20268.2 2.14E-06 22-Dec R.GNSIIMLEALER.V "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1344.7071 1.17 34338 20268 2 1344.709092 673.3608 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3776 - 912101 - - - 1.4546 - 2.701 0.426 - 616.1 1 2 0 0.002 12 0 0 0 3.61E+07 3.09E+07 - - - 4.8012 1 230117_WJC_METTL3_WT_vs_EV_F04.20269.20269.2 1.03E-06 22-Dec R.GNSIIMLEALER[166.11].V "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1354.7154 1.16 34339 20269 2 1354.71265 678.365 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3776.1 - 763357 - - - -2.0344 - 2.82 0.523 - 569.7 1 2 0 -0.0028 12 0 0 0 3.61E+07 3.10E+07 - - - 5.6308 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20271.20271.2 0.0267 20-Nov R.LEYC[160.03]EALAMLR.E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1367.6577 1.55 34341 20271 2 1367.658818 684.8361 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3776.4 - 629239 - - - 0.786 - 2.142 0.352 - 471.7 1 2 0 0.0011 11 0 0 0 1.26E+07 8.16E+06 - - - 3.7012 1 230117_WJC_METTL3_WT_vs_EV_F04.20272.20272.2 3.11E-07 20-Nov R.LEYC[160.03]EALAMLR[166.11].E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1377.666 1.57 34342 20272 2 1377.665419 689.8403 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3776.5 - 592905 - - - -0.4312 - 2.436 0.446 - 651.9 1 2 0 -0.0006 11 0 0 0 1.26E+07 8.06E+06 - - - 4.7436 1 230117_WJC_METTL3_WT_vs_EV_F04.20276.20276.2 0.00056 26-Dec K.GLIGNLYLNDSPLK[136.11].N sp|Q8IW92|GLBL2_HUMAN 1 1523.8439 -1 34346 20276 2 1523.848042 762.9292 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 5.83 3777 - 227485 - - - 2.7221 - 2.732 0.468 - 610.3 1 2 0 0.0041 14 0 0 0 0.00E+00 0.00E+00 - - - 5.0184 0.998 230117_WJC_METTL3_WT_vs_EV_F04.20277.20277.2 0.000144 12-Sep R.YMDLLWR.Y "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 995.4899 0.44 34347 20277 2 995.493953 498.7522 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 5.84 3777.1 - 220215 - - - 4.0985 - 1.501 0.376 - 288.7 1 2 0 0.0041 7 0 0 0 2.48E+06 5.68E+06 - - - 3.1037 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20281.20281.2 2.82E-06 24-Nov K.VLNSQAYLLFYER[166.11].L sp|Q9Y5T5|UBP16_HUMAN 1 1624.8489 -1 34351 20281 2 1624.849694 813.4317 Ubiquitin carboxyl-terminal hydrolase 16 OS=Homo sapiens OX=9606 GN=USP16 PE=1 SV=1 5.97 3777.7 - 195112 - - - 0.5114 - 2.092 0.366 - 232 1 2 0 0.0008 13 0 0 0 0.00E+00 0.00E+00 - - - 3.6384 0.9906 230117_WJC_METTL3_WT_vs_EV_F04.20284.20284.2 0.0112 22-Jun R.MFDMGFEPQVMR.L "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 1486.6407 -1 34354 20284 2 1486.634943 744.3276 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 4.37 3778.1 - 94865.8 - - - -3.8812 - 1.335 0.44 - 82.7 1 2 0 -0.0058 12 0 0 0 0.00E+00 0.00E+00 - - - 3.0493 1 230117_WJC_METTL3_WT_vs_EV_F04.20287.20287.2 1.02E-05 22-Nov R.GYELLFQPEVVR.L "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A804HJM1|A0A804HJM1_HUMAN,tr|A0A804HK15|A0A804HK15_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN,tr|A0A804HIL4|A0A804HIL4_HUMAN" 8 1448.7664 1.88 34356 20287 2 1448.771418 725.3905 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 4.53 3778.4 - 0 - - - 3.4871 - 2.307 0.534 - 534.9 1 2 0 0.0051 12 0 0 0 2.34E+06 1.25E+06 - - - 5.1831 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.20293.20293.2 0.00028 18-Aug K.DFLLQQTMLR[166.11].V sp|Q04760|LGUL_HUMAN 1 1273.6728 0.76 34362 20293 2 1273.675002 637.8437 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 5.84 3779.1 - 204368 - - - 1.7187 - 1.807 0.246 - 257.4 1 2 0 0.0022 10 0 0 0 1.05E+07 1.38E+07 - - - 2.5088 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20297.20297.2 0.000195 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 6480.88 34364 20297 2 1603.763881 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3779.6 - 9.31E+06 - - - -0.0368 - 1.882 0.522 - 234.1 1 2 0 -0.0001 12 0 0 0 1.29E+09 2.00E+05 - - - 4.5603 1 230117_WJC_METTL3_WT_vs_EV_F04.20299.20299.2 0.000482 18-Oct K.DFLLQQTMLR.V sp|Q04760|LGUL_HUMAN 1 1263.6645 0.75 34366 20299 2 1263.662844 632.8395 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 5.84 3779.8 - 5.46E+06 - - - -1.3445 - 2.276 0.464 - 447.5 1 2 0 -0.0017 10 0 0 0 1.05E+07 1.40E+07 - - - 4.7632 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20301.20301.2 0.114 14-Aug R.FDILC[160.03]VVR.D "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1020.5426 1.1 34368 20301 2 1020.543421 511.2786 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 5.83 3779.9 - 3.76E+06 - - - 0.7682 - 1.652 0.318 - 222.3 1 2 0 0.0008 8 0 0 0 1.26E+07 1.15E+07 - - - 2.9035 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.20302.20302.2 0.00117 16-Sep R.SIQMLTLLR[166.11].A "sp|Q13445|TMED1_HUMAN,tr|K7EIN4|K7EIN4_HUMAN,tr|K7EQ63|K7EQ63_HUMAN" 3 1083.635 1.28 34369 20302 2 1083.638053 542.8248 Transmembrane emp24 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TMED1 PE=1 SV=1 9.47 3780 - 3.02E+06 - - - 2.8441 - 2.01 0.384 - 285.5 1 2 0 0.0031 9 0 0 0 8.83E+06 6.90E+06 - - - 3.896 0.9964 230117_WJC_METTL3_WT_vs_EV_F04.20304.20304.2 0.0466 16-Sep R.YLLLHLLGR.G "sp|Q9UKI8|TLK1_HUMAN,sp|Q86UE8|TLK2_HUMAN,tr|A0A804HJX3|A0A804HJX3_HUMAN,tr|A0A804HKF1|A0A804HKF1_HUMAN,tr|J3KRK0|J3KRK0_HUMAN,tr|A0A804HK10|A0A804HK10_HUMAN,tr|A0A804HIB4|A0A804HIB4_HUMAN,tr|A0A804HJZ9|A0A804HJZ9_HUMAN,tr|J3QLK5|J3QLK5_HUMAN" 9 1096.6757 12.09 34371 20304 2 1096.673416 549.3451 Serine\threonine-protein kinase tousled-like 1 OS=Homo sapiens OX=9606 GN=TLK1 PE=1 SV=2 8.75 3780.2 - 1.26E+06 - - - -2.0827 - 1.767 0.291 - 355.6 1 2 0 -0.0023 9 0 0 0 4.08E+06 3.37E+05 - - - 2.8366 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.20308.20308.3 0.000198 Oct-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 328.48 34375 20308 3 1603.765114 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3780.7 - 1.89E+06 - - - 0.732 - 1.86 0.423 - 137.9 1 2 0 0.0012 12 0 0 0 1.50E+08 4.56E+05 - - - 4.9759 1 230117_WJC_METTL3_WT_vs_EV_F04.20309.20309.2 1.43E-06 18/34 K.IAIIGAGIGGTSAAYYLR.Q "sp|Q9UHG3|PCYOX_HUMAN,tr|F8W8W4|F8W8W4_HUMAN" 2 1765.9727 2.47 34376 20309 2 1765.974551 883.9936 Prenylcysteine oxidase 1 OS=Homo sapiens OX=9606 GN=PCYOX1 PE=1 SV=3 8.59 3780.8 - 652751 - - - 1.0651 - 3.489 0.589 - 893.3 1 2 0 0.0019 18 0 0 0 5.60E+06 2.26E+06 - - - 6.463 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.20315.20315.3 0.0612 Sep-36 K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.79 34380 20315 3 1176.719494 393.2476 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3781.5 - 0 - - - -1.2161 - 1.895 0.327 - 100.4 1 2 0 -0.0014 10 0 0 0 2.46E+07 1.38E+07 - - - 4.0521 0.9773 230117_WJC_METTL3_WT_vs_EV_F04.20318.20318.2 0.0323 14-Jun R.LMLLESWR[166.11].S "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 1056.5666 1.03 34383 20318 2 1056.561502 529.2906 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 6 3781.8 - 131437 - - - -4.7844 - 1.488 0.326 - 84.9 1 2 0 -0.0051 8 0 0 0 7.11E+06 6.91E+06 - - - 2.6459 0.9223 230117_WJC_METTL3_WT_vs_EV_F04.20319.20319.2 1.02 12-May R.EFALWLK.D "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 905.5011 0.56 34384 20319 2 905.499521 453.7578 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 6.1 3781.9 - 197760 - - - -1.7327 - 1.136 0.08 - 96.8 1 2 0 -0.0016 7 0 0 0 4.22E+06 7.58E+06 - - - 0.0354 1 230117_WJC_METTL3_WT_vs_EV_F04.20325.20325.2 0.183 16/24 R.LAAVALINAAIQK.G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1294.7973 1.27 34388 20325 2 1294.797795 648.4059 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3782.6 - 2.31E+06 - - - 0.4039 - 3.423 0.349 - 944.6 1 2 0 0.0005 13 0 0 0 1.04E+07 8.13E+06 - - - 4.7767 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.20326.20326.3 2.54E-06 14/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 328.48 34389 20326 3 1603.763382 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3782.7 - 7.95E+06 - - - -0.3479 - 2.397 0.568 - 297.6 1 2 0 -0.0006 12 0 0 0 1.50E+08 4.56E+05 - - - 7.2957 1 230117_WJC_METTL3_WT_vs_EV_F04.20328.20328.2 0.00575 13/24 R.LAAVALINAAIQK[136.11].G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1302.8115 1.27 34391 20328 2 1302.809849 652.413 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3782.9 - 1.52E+06 - - - -1.2458 - 2.684 0.43 - 606 1 2 0 -0.0016 13 0 0 0 1.04E+07 8.13E+06 - - - 4.7504 1 230117_WJC_METTL3_WT_vs_EV_F04.20333.20333.2 7.99E-05 13/24 R.TLVSGLLLEDSVR.V sp|A0A2Z4LIS9|FXO3B_HUMAN 1 1400.7875 1.85 34396 20333 2 1400.781658 701.401 Forkhead box protein O3B OS=Homo sapiens OX=9606 GN=FOXO3B PE=1 SV=1 4.37 3783.4 - 855559 - - - -4.1669 - 2.73 0.476 - 533.2 1 2 0 -0.0058 13 0 0 0 3.66E+06 1.98E+06 - - - 5.1325 1 230117_WJC_METTL3_WT_vs_EV_F04.20336.20336.2 2.72E-06 24-Sep R.VDLNEEETILIIR[166.11].R "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A0U1RQE1|A0A0U1RQE1_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A0U1RQZ9|A0A0U1RQZ9_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8YCY3|A0A2R8YCY3_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YDA1|A0A2R8YDA1_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8YFV8|A0A2R8YFV8_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A2R8Y4R6|A0A2R8Y4R6_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 25 1565.854 -1 34399 20336 2 1565.849316 783.9343 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4 3783.8 - 0 - - - -2.9964 - 2.336 0.49 - 338.7 1 2 0 -0.0047 13 0 0 0 0.00E+00 0.00E+00 - - - 4.8362 1 230117_WJC_METTL3_WT_vs_EV_F04.20337.20337.2 7.61E-05 28-Nov K.LGLNC[160.03]AIYATIPVYK.M sp|Q9P2I0|CPSF2_HUMAN 1 1694.9066 29.51 34400 20337 2 1694.90858 848.4606 Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2 8.18 3783.9 - 0 - - - 1.1889 - 2.435 0.471 - 250.8 1 2 0 0.002 15 0 0 0 1.47E+06 4.98E+04 - - - 4.7071 1 230117_WJC_METTL3_WT_vs_EV_F04.20344.20344.2 6.02E-10 14/24 R.WSTLVEDYGMELR.K sp|O00232|PSD12_HUMAN 1 1597.7446 0.36 34405 20344 2 1597.745101 799.8796 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.14 3784.6 - 1.86E+06 - - - 0.286 - 2.667 0.707 - 847.1 1 2 0 0.0005 13 0 0 0 9.47E+06 2.64E+07 - - - 6.7804 1 230117_WJC_METTL3_WT_vs_EV_F04.20345.20345.2 4.24E-05 14/22 K.TVLLLADQMISR.L "sp|P48730|KC1D_HUMAN,sp|P49674|KC1E_HUMAN,tr|B0QY36|B0QY36_HUMAN,tr|B0QY34|B0QY34_HUMAN,tr|H7BYT1|H7BYT1_HUMAN,tr|J3QQI9|J3QQI9_HUMAN,tr|A0A669KBC0|A0A669KBC0_HUMAN,tr|H0Y645|H0Y645_HUMAN,tr|B0QY35|B0QY35_HUMAN,tr|H0Y2N6|H0Y2N6_HUMAN" 10 1358.7592 1.33 34406 20345 2 1358.761268 680.3869 Casein kinase I isoform delta OS=Homo sapiens OX=9606 GN=CSNK1D PE=1 SV=2 5.5 3784.7 - 1.16E+06 - - - 1.5426 - 3.042 0.495 - 856 1 2 0 0.0021 12 0 0 0 6.49E+06 4.87E+06 - - - 5.6236 1 230117_WJC_METTL3_WT_vs_EV_F04.20349.20349.2 9.84E-06 14/24 K.C[160.03]LAPTYLGEFSLR.G "sp|P49366|DHYS_HUMAN,tr|Q5J8M5|Q5J8M5_HUMAN,tr|M0R264|M0R264_HUMAN,tr|A0A087WZK0|A0A087WZK0_HUMAN,tr|M0R1T2|M0R1T2_HUMAN" 5 1525.7599 1.47 34410 20349 2 1525.757947 763.8872 Deoxyhypusine synthase OS=Homo sapiens OX=9606 GN=DHPS PE=1 SV=1 5.99 3785.1 - 631713 - - - -1.28 - 2.417 0.581 - 684.4 1 2 0 -0.002 13 0 0 0 2.09E+06 1.42E+06 - - - 5.5967 0.9951 230117_WJC_METTL3_WT_vs_EV_F04.20350.20350.2 0.00827 20-Sep R.VYGALMWSLGK[136.11].V "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|C9JDQ8|C9JDQ8_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 7 1231.6515 2.34 34411 20350 2 1231.648751 616.833 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 8.56 3785.2 - 536794 - - - -2.2044 - 1.363 0.364 - 150.7 1 2 0 -0.0027 11 0 0 0 6.91E+06 2.95E+06 - - - 2.5664 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20351.20351.3 0.0104 Dec-48 R.LAAVALINAAIQK.G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1294.7973 1.1 34412 20351 3 1294.798674 432.6064 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3785.4 - 453494 - - - 1.0828 - 2.212 0.288 - 265 1 2 0 0.0014 13 0 0 0 2.85E+06 2.58E+06 - - - 3.903 1 230117_WJC_METTL3_WT_vs_EV_F04.20354.20354.2 0.000444 13/22 K.TVLLLADQMISR[166.11].L "sp|P48730|KC1D_HUMAN,sp|P49674|KC1E_HUMAN,tr|B0QY36|B0QY36_HUMAN,tr|B0QY34|B0QY34_HUMAN,tr|H7BYT1|H7BYT1_HUMAN,tr|J3QQI9|J3QQI9_HUMAN,tr|A0A669KBC0|A0A669KBC0_HUMAN,tr|H0Y645|H0Y645_HUMAN,tr|B0QY35|B0QY35_HUMAN,tr|H0Y2N6|H0Y2N6_HUMAN" 10 1368.7674 1.33 34414 20354 2 1368.767029 685.391 Casein kinase I isoform delta OS=Homo sapiens OX=9606 GN=CSNK1D PE=1 SV=2 5.5 3785.8 - 100803 - - - -0.3017 - 2.947 0.473 - 687.8 1 2 0 -0.0004 12 0 0 0 6.49E+06 4.87E+06 - - - 5.3782 1 230117_WJC_METTL3_WT_vs_EV_F04.20358.20358.2 8.47E-07 17/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 34417 20358 2 1343.609819 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3786.3 - 609802 - - - -1.2228 - 2.969 0.56 - 1156.4 1 1 0 -0.0016 10 0 0 0 5.46E+06 0.00E+00 - - - 6.2142 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20362.20362.2 0.0849 18-Oct K.INEWLTLVEK[136.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1251.6954 0.99 34421 20362 2 1251.698681 626.855 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.53 3786.8 - 403379 - - - 2.5901 - 2.336 0.347 - 502.8 1 2 0 0.0032 10 0 0 0 7.42E+06 7.53E+06 - - - 3.9712 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20363.20363.2 8.43E-07 13/20 R.VYGALMWSLGK.V "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|C9JDQ8|C9JDQ8_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 7 1223.6373 2.34 34422 20363 2 1223.637215 612.8259 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 8.56 3786.9 - 269285 - - - -0.0417 - 2.271 0.357 - 461.6 1 2 0 -0.0001 11 0 0 0 6.91E+06 2.95E+06 - - - 3.8967 0.9967 230117_WJC_METTL3_WT_vs_EV_F04.20364.20364.2 0.00156 12-Aug K.LWDLYLR.T "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 977.5335 2.65 34423 20364 2 977.536319 489.774 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.84 3787 - 198978 - - - 2.9329 - 1.655 0.156 - 288.9 1 2 0 0.0029 7 0 0 0 7.92E+06 2.99E+06 - - - 1.7886 0.9871 230117_WJC_METTL3_WT_vs_EV_F04.20365.20365.2 0.144 16-Jun R.GLYDFYLPR.E "sp|Q9Y2U9|KLDC2_HUMAN,tr|G3V3U8|G3V3U8_HUMAN,tr|G3V2H2|G3V2H2_HUMAN" 3 1142.576 15.37 34424 20365 2 1142.581292 572.2953 Kelch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=KLHDC2 PE=1 SV=1 5.83 3787.1 - 150638 - - - 4.5914 - 1.364 0.217 - 86 1 2 0 0.0052 9 0 0 0 4.57E+06 2.97E+05 - - - 1.5402 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20368.20368.2 0.00772 16-Sep K.ELALSALLK[136.11].F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 964.6048 1.06 34425 20368 2 964.605167 483.3097 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3787.6 - 221094 - - - 0.3463 - 1.813 0.311 - 266.4 1 2 0 0.0003 9 0 0 0 2.40E+07 2.27E+07 - - - 3.0593 1 230117_WJC_METTL3_WT_vs_EV_F04.20369.20369.2 1.18E-06 18-Oct K.GPDWILGEIK.T "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 6 1126.6023 4.46 34426 20369 2 1126.600153 564.3084 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 4.37 3787.6 - 240324 - - - -1.8702 - 2.165 0.535 - 443.6 1 2 0 -0.0021 10 0 0 0 7.82E+06 1.76E+06 - - - 5.1479 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.20373.20373.2 0.124 12-Jun R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 999 34430 20373 2 808.432958 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 3788 - 552699 - - - -0.1385 - 1.318 0.266 - 83.6 1 2 0 -0.0001 7 0 0 0 4.13E+06 0.00E+00 - - - 1.8805 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.20383.20383.2 3.02E-05 18-Aug K.GPDWILGEIK[136.11].T "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 6 1134.6165 3.8 34440 20383 2 1134.622188 568.3155 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 4.37 3789.2 - 84368.3 - - - 5.0484 - 1.836 0.443 - 214.3 1 2 0 0.0057 10 0 0 0 6.67E+06 1.76E+06 - - - 4.0072 1 230117_WJC_METTL3_WT_vs_EV_F04.20385.20385.2 0.00162 13/22 K.VESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1404.75 1.61 34442 20385 2 1404.753741 703.3823 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3789.5 - 75548.2 - - - 2.6296 - 2.707 0.482 - 645.4 1 2 0 0.0037 12 0 0 0 7.88E+06 4.89E+06 - - - 5.2201 1 230117_WJC_METTL3_WT_vs_EV_F04.20386.20386.2 3.34E-05 13/22 K.LMSALLSGLTDR[166.11].N "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN" 3 1285.6939 -1 34443 20386 2 1285.697419 643.8542 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.84 3789.6 - 0 - - - 2.7044 - 2.245 0.479 - 519.7 1 2 0 0.0035 12 0 0 0 0.00E+00 0.00E+00 - - - 4.7056 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.20387.20387.2 0.00105 22-Nov R.IMVANIEEVLQR[166.11].G "sp|O75396|SC22B_HUMAN,tr|A0A087X1A9|A0A087X1A9_HUMAN" 2 1423.7733 -1 34444 20387 2 1423.770766 712.8939 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 4.53 3789.7 - 77781.4 - - - -1.7482 - 2.394 0.428 - 493.6 1 2 0 -0.0025 12 0 0 0 0.00E+00 0.00E+00 - - - 4.4983 0.999 230117_WJC_METTL3_WT_vs_EV_F04.20393.20393.2 0.00864 16-Nov K.EIIDLVLDR[166.11].L "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 9 1094.6211 3.38 34449 20393 2 1094.620064 548.3178 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.03 3790.3 - 4.69E+06 - - - -0.9419 - 2.006 0.353 - 518.3 1 2 0 -0.001 9 0 0 0 5.73E+08 1.70E+08 - - - 3.6619 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.20395.20395.2 0.0012 16-Oct K.ELALSALLK.F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 956.5906 1.06 34451 20395 2 956.588912 479.3026 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3790.5 - 2.00E+06 - - - -1.7991 - 1.993 0.391 - 336.8 1 2 0 -0.0017 9 0 0 0 2.40E+07 2.27E+07 - - - 3.9236 0.999 230117_WJC_METTL3_WT_vs_EV_F04.20396.20396.2 0.0265 14-Sep K.QELLELFK.E "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1018.5699 1.19 34452 20396 2 1018.569795 510.2922 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 4.53 3790.7 - 1.12E+06 - - - -0.1011 - 1.656 0.321 - 282.2 1 2 0 -0.0001 8 0 0 0 1.15E+07 9.59E+06 - - - 2.9331 1 230117_WJC_METTL3_WT_vs_EV_F04.20397.20397.2 3.71E-06 22-Dec R.LLTFMGMAVENK[136.11].E "sp|Q7L2H7|EIF3M_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 2 1360.6974 1.03 34453 20397 2 1360.695904 681.356 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6 3790.8 - 1.08E+06 - - - -1.1215 - 2.415 0.576 - 451.6 1 2 0 -0.0015 12 0 0 0 8.76E+06 8.54E+06 - - - 5.6148 1 230117_WJC_METTL3_WT_vs_EV_F04.20402.20402.2 5.38E-09 13/20 K.C[160.03]GPMVLDALIK.L "sp|P21912|SDHB_HUMAN,tr|A0A087WWT1|A0A087WWT1_HUMAN,tr|A0A087WXX8|A0A087WXX8_HUMAN" 3 1215.6356 -1 34458 20402 2 1215.634077 608.8251 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.83 3791.5 - 617077 - - - -1.2125 - 2.639 0.579 - 537.5 1 2 0 -0.0015 11 0 0 0 0.00E+00 0.00E+00 - - - 5.9422 0.9872 230117_WJC_METTL3_WT_vs_EV_F04.20404.20404.2 0.158 22-Aug K.VILLDPSIIEAK.M sp|Q07617|SPAG1_HUMAN 1 1309.7857 6 34460 20404 2 1309.786033 655.9001 Sperm-associated antigen 1 OS=Homo sapiens OX=9606 GN=SPAG1 PE=1 SV=3 4.37 3791.7 - 497765 - - - 0.2512 - 1.103 0.16 - 94.8 1 2 0 0.0003 12 0 0 0 1.90E+06 3.16E+05 - - - 0.4806 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20405.20405.2 0.000524 16-Sep K.DLFQVAFNR.V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN" 15 1108.5665 1.85 34461 20405 2 1108.567334 555.2905 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.84 3791.8 - 434986 - - - 0.7135 - 1.581 0.41 - 218.3 1 2 0 0.0008 9 0 0 0 2.00E+06 1.08E+06 - - - 3.3942 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.20406.20406.2 0.0327 16-Sep K.LISLFQAMK.K "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1049.5943 3.16 34462 20406 2 1049.593859 525.8044 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.75 3792 - 421873 - - - -0.4564 - 1.715 0.323 - 165.1 1 2 0 -0.0005 9 0 0 0 5.85E+06 1.85E+06 - - - 2.9871 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.20410.20410.2 0.000352 18-Aug K.LVFPQDLLEK[136.11].G "sp|Q8TCT9|HM13_HUMAN,tr|A0A3B3IT72|A0A3B3IT72_HUMAN,tr|A0A0S2Z6F0|A0A0S2Z6F0_HUMAN,tr|A0A3B3IUB5|A0A3B3IUB5_HUMAN,tr|A0A075B6F6|A0A075B6F6_HUMAN" 5 1208.6896 1.33 34465 20410 2 1208.688719 605.3521 Minor histocompatibility antigen H13 OS=Homo sapiens OX=9606 GN=HM13 PE=1 SV=1 4.37 3792.5 - 1.01E+06 - - - -0.7496 - 1.625 0.378 - 166.4 1 2 0 -0.0009 10 0 0 0 7.84E+06 5.89E+06 - - - 3.1878 0.999 230117_WJC_METTL3_WT_vs_EV_F04.20413.20413.2 0.0211 18-Sep K.AEVLWLMGAK.S sp|O94906|PRP6_HUMAN 1 1116.6002 0.98 34468 20413 2 1116.59907 559.3074 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.05 3792.7 - 2.73E+06 - - - -0.969 - 1.919 0.384 - 257.4 1 2 0 -0.0011 10 0 0 0 1.64E+07 1.68E+07 - - - 3.6963 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20414.20414.2 0.00217 18-Sep K.AEVLWLMGAK[136.11].S sp|O94906|PRP6_HUMAN 1 1124.6144 1.01 34469 20414 2 1124.617187 563.3145 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.05 3792.8 - 2.67E+06 - - - 2.5209 - 1.851 0.448 - 330.8 1 2 0 0.0028 10 0 0 0 1.71E+07 1.68E+07 - - - 4.0677 1 230117_WJC_METTL3_WT_vs_EV_F04.20415.20415.2 1.73E-05 22-Oct K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.8 34470 20415 2 1317.708316 659.862 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3792.8 - 2.34E+06 - - - -0.8037 - 2.265 0.54 - 189 1 2 0 -0.0011 12 0 0 0 2.16E+08 2.71E+08 - - - 5.1803 1 230117_WJC_METTL3_WT_vs_EV_F04.20418.20418.2 1.11E-10 17/30 K.IITLEEGDIILTGTPK.G sp|Q6P587|FAHD1_HUMAN 1 1711.9608 -1 34473 20418 2 1711.960431 856.9877 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3793.2 - 1.17E+06 - - - -0.1969 - 3.361 0.645 - 902.3 1 2 0 -0.0003 16 0 0 0 0.00E+00 0.00E+00 - - - 6.7852 1 230117_WJC_METTL3_WT_vs_EV_F04.20421.20421.2 0.000108 18-Oct -.MFLYNLTLQR.A "sp|Q15393|SF3B3_HUMAN,tr|H3BMB0|H3BMB0_HUMAN,tr|I3L4G7|I3L4G7_HUMAN" 3 1297.6853 0.19 34476 20421 2 1297.684888 649.8499 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.5 3793.5 - 887062 - - - -0.3005 - 2.318 0.512 - 377.6 1 2 0 -0.0004 10 0 0 0 2.59E+07 1.36E+08 - - - 5.1692 0.995 230117_WJC_METTL3_WT_vs_EV_F04.20423.20423.2 0.00021 16-Sep R.YEGFFGLYR[166.11].G "sp|O75746|CMC1_HUMAN,sp|Q9UJS0|CMC2_HUMAN" 2 1160.553 -1 34478 20423 2 1160.550916 581.2838 Calcium-binding mitochondrial carrier protein Aralar1 OS=Homo sapiens OX=9606 GN=SLC25A12 PE=1 SV=2 6 3793.7 - 752314 - - - -1.8086 - 1.738 0.224 - 252.1 1 2 0 -0.0021 9 0 0 0 0.00E+00 0.00E+00 - - - 2.2939 0.979 230117_WJC_METTL3_WT_vs_EV_F04.20425.20425.2 2.43 20-Jun R.YLLLGQGDFIR.H "sp|Q96CW5|GCP3_HUMAN,tr|A0A3B3ITE3|A0A3B3ITE3_HUMAN" 2 1293.7081 -1 34480 20425 2 1293.708632 647.8613 Gamma-tubulin complex component 3 OS=Homo sapiens OX=9606 GN=TUBGCP3 PE=1 SV=2 5.84 3793.9 - 238454 - - - 0.3942 - 1.206 0.075 - 121.9 1 2 0 0.0005 11 0 0 0 0.00E+00 0.00E+00 - - - 0.1015 0.9559 230117_WJC_METTL3_WT_vs_EV_F04.20428.20428.2 1.86 22-May -.MPPYTVVYFPVR[166.11].G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1477.7667 0.61 34483 20428 2 1477.772081 739.8906 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 8.34 3794.3 - 0 - - - 3.6325 - 1.123 0.135 - 30.2 3 2 0 0.0054 12 0 0 0 9.59E+05 1.57E+06 - - - 0.1285 1 230117_WJC_METTL3_WT_vs_EV_F04.20430.20430.2 2.25E-07 22-Dec R.LLTFMGMAVENK.E "sp|Q7L2H7|EIF3M_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 2 1352.6832 1.02 34484 20430 2 1352.686303 677.3489 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6 3794.6 - 138016 - - - 2.2718 - 2.482 0.569 - 547.6 1 2 0 0.0031 12 0 0 0 8.76E+06 8.58E+06 - - - 5.6346 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.20434.20434.2 6.30E-05 20-Oct K.GVPTGFILPIR[166.11].D "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1178.7051 3.19 34485 20434 2 1178.702781 590.3598 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 3795.1 - 1.06E+06 - - - -1.9666 - 1.857 0.446 - 344.5 1 2 0 -0.0023 11 0 0 0 1.28E+08 4.03E+07 - - - 4.0089 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.20435.20435.2 0.031 14-Jun R.EIFNFVLK[136.11].A sp|P78527|PRKDC_HUMAN 1 1016.5786 1.13 34486 20435 2 1016.57929 509.2966 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6.1 3795.2 - 547860 - - - 0.661 - 1.262 0.277 - 123.2 1 2 0 0.0007 8 0 0 0 1.46E+07 1.30E+07 - - - 1.7885 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.20441.20441.2 0.0158 18-Nov K.VGDPVYLLGQ.- "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN" 2 1059.5601 - 34492 20441 2 1059.561602 530.7873 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 3.8 3796 - 777107 - - - 1.4544 - 1.909 0.281 - 389.8 1 2 0 0.0015 10 0 0 0 - - - - - 2.9208 0.9506 230117_WJC_METTL3_WT_vs_EV_F04.20444.20444.2 0.00813 18-Aug R.WFTHASPTLF.N "sp|P23921|RIR1_HUMAN,tr|H0YCY7|H0YCY7_HUMAN" 2 1205.5869 - 34495 20444 2 1205.587266 603.8007 Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1 6.74 3796.3 - 439833 - - - 0.2663 - 1.596 0.387 - 131.9 1 1 0 0.0003 10 0 0 0 - - - - - 3.2042 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.20446.20446.2 0.0194 24-Nov R.LELYAQATEALLK.T "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1461.8079 2.94 34497 20446 2 1461.804459 731.9112 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 4.53 3796.6 - 237382 - - - -2.3512 - 2.273 0.377 - 291.7 1 2 0 -0.0034 13 0 0 0 5.17E+06 1.76E+06 - - - 3.9318 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.20448.20448.2 0.000168 22-Dec R.VALDMTTLTIMR[166.11].Y "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 4 1373.7286 0.97 34499 20448 2 1373.726067 687.8716 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.81 3796.9 - 0 - - - -1.8534 - 2.429 0.43 - 576.5 1 2 0 -0.0025 12 0 0 0 9.71E+06 1.00E+07 - - - 4.5513 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20449.20449.2 0.000535 24-Dec K.LILLITQVTASEK[136.11].T sp|Q15061|WDR43_HUMAN 1 1435.8741 0.95 34500 20449 2 1435.874764 718.9443 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3797 - 0 - - - 0.4402 - 2.421 0.443 - 386.4 1 2 0 0.0006 13 0 0 0 5.27E+06 5.52E+06 - - - 4.5821 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.20450.20450.2 0.000239 18-Sep K.FTMVQVWPVR.Q "sp|P38606|VATA_HUMAN,tr|C9JA17|C9JA17_HUMAN,tr|C9JVW8|C9JVW8_HUMAN" 3 1261.6641 1.42 34501 20450 2 1261.661027 631.8394 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 9.75 3797.1 - 227965 - - - -2.4745 - 1.886 0.488 - 396.1 1 2 0 -0.0031 10 0 0 0 6.87E+06 4.84E+06 - - - 4.4154 0.8848 230117_WJC_METTL3_WT_vs_EV_F04.20454.20454.2 0.139 22-Mar K.TVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1309.6952 0.8 34503 20454 2 1309.689988 655.8549 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3797.7 - 4.58E+06 - - - -3.9605 - 0.744 0.329 - 16.4 1 2 0 -0.0052 12 0 0 0 2.16E+08 2.71E+08 - - - 0.6913 0.9894 230117_WJC_METTL3_WT_vs_EV_F04.20456.20456.2 0.00282 14-Jul R.EIFNFVLK.A sp|P78527|PRKDC_HUMAN 1 1008.5644 1.13 34505 20456 2 1008.560588 505.2895 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6.1 3797.8 - 317857 - - - -3.7975 - 1.444 0.364 - 183 1 2 0 -0.0038 8 0 0 0 1.46E+07 1.30E+07 - - - 2.8364 0.9343 230117_WJC_METTL3_WT_vs_EV_F04.20457.20457.3 0.119 May-44 K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.56 34506 20457 3 1317.703966 440.2437 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3797.8 - 273868 - - - -4.1049 - 1.118 0.296 - 47.9 1 2 0 -0.0054 12 0 0 0 5.46E+06 9.81E+06 - - - 2.1478 0.9834 230117_WJC_METTL3_WT_vs_EV_F04.20458.20458.2 0.000593 14-Sep R.LLDFLNVK[136.11].N sp|Q8NDZ4|DIK2A_HUMAN 1 968.5786 0.64 34507 20458 2 968.573997 485.2966 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 5.84 3797.9 - 0 - - - -4.7709 - 1.524 0.368 - 181.1 1 2 0 -0.0046 8 0 0 0 7.82E+06 1.21E+07 - - - 3.0283 1 230117_WJC_METTL3_WT_vs_EV_F04.20459.20459.2 1.69E-05 28-Nov K.GVYPDLLATSGDYLR[166.11].V sp|P61962|DCAF7_HUMAN 1 1648.8336 -1 34508 20459 2 1648.82366 825.4241 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3797.9 - 287575 - - - -6.0327 - 2.193 0.517 - 210.4 1 2 0 -0.0099 15 0 0 0 0.00E+00 0.00E+00 - - - 4.7871 0.9926 230117_WJC_METTL3_WT_vs_EV_F04.20460.20460.2 0.000604 14-Sep R.LLDFLNVK.N sp|Q8NDZ4|DIK2A_HUMAN 1 960.5644 0.64 34509 20460 2 960.560751 481.2895 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 5.84 3798 - 0 - - - -3.8175 - 1.682 0.369 - 175.4 1 2 0 -0.0037 8 0 0 0 7.82E+06 1.21E+07 - - - 3.3335 0.9701 230117_WJC_METTL3_WT_vs_EV_F04.20462.20462.2 0.0324 16-Jul K.DVMDALILK[136.11].M sp|Q8N1G4|LRC47_HUMAN 1 1024.5718 1 34511 20462 2 1024.567276 513.2932 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 4.21 3798.1 - 0 - - - -4.4331 - 1.309 0.311 - 117.3 1 2 0 -0.0045 9 0 0 0 1.08E+07 1.07E+07 - - - 2.1156 1 230117_WJC_METTL3_WT_vs_EV_F04.20464.20464.2 2.08E-05 22-Dec R.IRDLLYEQYAIV.- sp|Q9P2I0|CPSF2_HUMAN 1 1494.8082 8.98 34513 20464 2 1494.805487 748.4114 Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2 4.37 3798.4 - 267673 - - - -1.835 - 2.03 0.515 - 387.9 1 2 1 -0.0027 12 0 0 0 4.96E+06 5.53E+05 - - - 4.7069 0.9845 230117_WJC_METTL3_WT_vs_EV_F04.20465.20465.2 0.516 14-Jun -.MLPLSLLK.T "sp|Q9Y4Z0|LSM4_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 913.5671 12.68 34514 20465 2 913.566296 457.7908 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 8.5 3798.4 - 0 - - - -0.8374 - 1.155 0.178 - 119.1 1 2 0 -0.0008 8 0 0 0 7.48E+06 5.90E+05 - - - 0.7901 1 230117_WJC_METTL3_WT_vs_EV_F04.20466.20466.2 0.00158 15/26 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.84 34515 20466 2 1487.768518 744.8959 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3798.6 - 0 - - - -5.8792 - 2.738 0.507 - 593.7 1 2 0 -0.0087 14 0 0 0 2.94E+07 1.60E+07 - - - 5.3105 1 230117_WJC_METTL3_WT_vs_EV_F04.20467.20467.2 2.24E-07 18/34 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 2.08 34516 20467 2 1968.06644 985.0433 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3798.7 - 0 - - - -2.8505 - 2.67 0.614 - 597.7 1 2 0 -0.0056 18 0 0 0 3.52E+06 1.69E+06 - - - 5.9887 0.997 230117_WJC_METTL3_WT_vs_EV_F04.20468.20468.2 0.00531 24-Nov R.LELYAQATEALLK.T "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1461.8079 2.94 34517 20468 2 1461.803446 731.9112 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 4.53 3798.8 - 0 - - - -3.0442 - 2.191 0.416 - 309.7 1 2 0 -0.0044 13 0 0 0 5.17E+06 1.76E+06 - - - 4.1253 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20469.20469.3 0.006 Nov-40 R.LHQLLALTLWK.E "sp|Q7L5D6|GET4_HUMAN,tr|C9JPA8|C9JPA8_HUMAN,tr|C9JHN8|C9JHN8_HUMAN,tr|C9JY46|C9JY46_HUMAN" 4 1334.8074 1.6 34518 20469 3 1334.805441 445.9431 Golgi to ER traffic protein 4 homolog OS=Homo sapiens OX=9606 GN=GET4 PE=1 SV=1 8.76 3798.9 - 656187 - - - -1.4998 - 2.277 0.418 - 119.3 1 2 0 -0.002 11 0 0 0 1.74E+06 1.09E+06 - - - 5.5373 0.9918 230117_WJC_METTL3_WT_vs_EV_F04.20470.20470.2 0.04 20-Jul K.ILPGLYIGNFK.D "sp|Q9NRW4|DUS22_HUMAN,tr|S4R459|S4R459_HUMAN" 2 1233.7121 -1 34519 20470 2 1233.709233 617.8633 Dual specificity protein phosphatase 22 OS=Homo sapiens OX=9606 GN=DUSP22 PE=1 SV=1 8.59 3799 - 0 - - - -2.3604 - 1.494 0.272 - 90.4 1 2 0 -0.0029 11 0 0 0 0.00E+00 0.00E+00 - - - 2.1351 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.20471.20471.2 0.00719 20-Sep K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 64.29 34520 20471 2 1184.715225 593.3637 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3799.1 - 0 - - - 1.9853 - 1.352 0.244 - 146.4 1 2 0 0.0024 11 0 0 0 3.05E+06 4.75E+04 - - - 1.6583 1 230117_WJC_METTL3_WT_vs_EV_F04.20476.20476.2 0.000163 Dec-34 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 -1 34524 20476 2 1976.077718 989.0504 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3799.6 - 0 - - - -4.3176 - 2.19 0.524 - 220.4 1 2 0 -0.0085 18 0 0 0 0.00E+00 0.00E+00 - - - 4.8358 1 230117_WJC_METTL3_WT_vs_EV_F04.20484.20484.2 3.59E-11 16/26 R.YSALFLGVAYGATR[166.11].Y sp|P56385|ATP5I_HUMAN 1 1497.7855 1.84 34530 20484 2 1497.78507 749.9 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3800.5 - 506832 - - - -0.3105 - 2.997 0.665 - 796.9 1 2 0 -0.0005 14 0 0 0 2.94E+07 1.60E+07 - - - 6.7069 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.20486.20486.3 0.000256 14/52 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.54 34532 20486 3 1487.777807 496.933 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3800.7 - 249777 - - - 0.3643 - 1.897 0.436 - 141.9 1 2 0 0.0005 14 0 0 0 4.09E+06 2.66E+06 - - - 5.1024 0.996 230117_WJC_METTL3_WT_vs_EV_F04.20492.20492.2 0.0694 16-Jul K.LLYTFPGWK[136.11].V "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1131.6208 1.64 34538 20492 2 1131.622568 566.8177 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 8.59 3801.5 - 182127 - - - 1.5473 - 1.276 0.191 - 95.9 1 2 0 0.0018 9 0 0 0 1.57E+07 9.56E+06 - - - 1.1563 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.20497.20497.2 0.000112 14-Sep K.AWGILTFK[136.11].G "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 942.5418 1.32 34541 20497 2 942.540315 472.2782 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 8.8 3802.1 - 1.99E+06 - - - -1.6169 - 1.754 0.499 - 391.4 1 2 0 -0.0015 8 0 0 0 8.36E+07 6.34E+07 - - - 4.4208 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20498.20498.2 0.00154 14-Oct K.AWGILTFK.G "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 934.5276 1.32 34542 20498 2 934.528121 468.2711 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 8.8 3802.3 - 1.77E+06 - - - 0.5158 - 1.741 0.366 - 476.2 1 2 0 0.0005 8 0 0 0 8.36E+07 6.34E+07 - - - 3.4163 1 230117_WJC_METTL3_WT_vs_EV_F04.20499.20499.2 0.000145 13/18 K.VLEAELLVLR[166.11].Q sp|P07196|NFL_HUMAN 1 1163.7153 0.83 34543 20499 2 1163.71665 582.8649 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.53 3802.4 - 1.21E+06 - - - 1.1343 - 2.374 0.495 - 586.6 1 2 0 0.0013 10 0 0 0 4.68E+06 5.63E+06 - - - 5.11 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20501.20501.2 3.23E-06 20-Oct K.GIFNGFSVTLK[136.11].E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1189.6587 1.55 34545 20501 2 1189.661295 595.8366 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3802.7 - 823973 - - - 2.2158 - 2.047 0.413 - 223.9 1 2 0 0.0026 11 0 0 0 1.45E+07 9.31E+06 - - - 4.0286 0.999 230117_WJC_METTL3_WT_vs_EV_F04.20503.20503.2 0.0737 14-Aug R.VLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 881.6062 1.38 34547 20503 2 881.605869 441.8104 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3802.9 - 581288 - - - -0.4015 - 1.746 0.324 - 183.7 1 2 0 -0.0004 8 0 0 0 3.40E+07 2.45E+07 - - - 3.1148 0.9328 230117_WJC_METTL3_WT_vs_EV_F04.20504.20504.2 0.00374 18-Jul R.LGFEGGQTPF.Y "sp|Q9P015|RM15_HUMAN,tr|E5RHF4|E5RHF4_HUMAN" 2 1051.4975 - 34548 20504 2 1051.497737 526.756 "39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1" 4 3803.1 - 464860 - - - 0.2625 - 1.391 0.382 - 116.8 1 1 0 0.0003 10 0 0 0 - - - - - 2.7836 0.9803 230117_WJC_METTL3_WT_vs_EV_F04.20510.20510.2 0.00335 22-Oct K.FLETVELQISLK.N sp|P62906|RL10A_HUMAN 1 1418.8021 1.08 34554 20510 2 1418.811481 710.4083 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.53 3803.8 - 162034 - - - 6.6246 - 1.611 0.288 - 137.5 1 2 0 0.0094 12 0 0 0 2.89E+06 2.67E+06 - - - 2.4199 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.20514.20514.2 0.000675 20-Nov K.GVPTGFILPIR.D "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1168.6968 24.77 34557 20514 2 1168.697039 585.3557 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 3804.3 - 1.31E+06 - - - 0.1797 - 1.909 0.285 - 282.4 1 2 0 0.0002 11 0 0 0 9.13E+06 3.69E+05 - - - 2.8951 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20515.20515.2 6.58E-06 20-Nov K.GIFNGFSVTLK.E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1181.6445 1.55 34558 20515 2 1181.644392 591.8295 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3804.4 - 3.73E+06 - - - -0.0567 - 2.135 0.45 - 325.5 1 2 0 -0.0001 11 0 0 0 1.45E+07 9.31E+06 - - - 4.4165 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20516.20516.2 0.00463 14-Oct R.VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 891.6145 1.38 34559 20516 2 891.614689 446.8145 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3804.5 - 3.14E+06 - - - 0.2198 - 2.016 0.261 - 485 1 2 0 0.0002 8 0 0 0 3.40E+07 2.45E+07 - - - 3.0832 1 230117_WJC_METTL3_WT_vs_EV_F04.20517.20517.2 5.02E-07 14/24 R.GAVGALLVYDIAK.H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1288.7391 1.47 34560 20517 2 1288.740414 645.3768 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3804.7 - 2.34E+06 - - - 1.0289 - 3.057 0.597 - 1103.6 1 2 0 0.0013 13 0 0 0 8.08E+07 5.49E+07 - - - 6.318 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20518.20518.2 0.00015 16-Oct R.LVSYYYFLR.F sp|Q7LGA3|HS2ST_HUMAN 1 1222.6386 0.77 34561 20518 2 1222.639642 612.3266 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 8.5 3804.8 - 1.60E+06 - - - 0.8146 - 1.927 0.453 - 392.2 1 2 0 0.001 9 0 0 0 1.03E+07 1.34E+07 - - - 4.2843 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20519.20519.2 0.115 13/20 K.FMELLEPLNER[166.11].K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1399.7045 0.83 34562 20519 2 1399.705621 700.8595 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.25 3804.9 - 633338 - - - 0.7959 - 2.116 0.397 - 573.9 1 2 0 0.0011 11 0 0 0 2.55E+06 3.07E+06 - - - 4.0005 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.20521.20521.2 0.00868 16-Aug K.DLSDFPLIK.K "sp|P20585|MSH3_HUMAN,tr|A0A590UJN8|A0A590UJN8_HUMAN,tr|A0A590UKC9|A0A590UKC9_HUMAN,tr|A0A590UJW0|A0A590UJW0_HUMAN" 4 1046.5648 1.79 34564 20521 2 1046.565234 524.2897 DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4 4.21 3805.2 - 542430 - - - 0.4032 - 1.557 0.336 - 162.4 1 2 0 0.0004 9 0 0 0 2.14E+06 1.19E+06 - - - 2.8035 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20522.20522.2 0.00117 20-Dec R.LLGAALPLLTK[136.11].E "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1116.7362 1.06 34565 20522 2 1116.736851 559.3754 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 8.75 3805.3 - 534859 - - - 0.5991 - 2.116 0.259 - 286.1 1 2 0 0.0007 11 0 0 0 4.15E+06 3.92E+06 - - - 2.9814 1 230117_WJC_METTL3_WT_vs_EV_F04.20523.20523.2 0.0527 13/20 R.LLGAALPLLTK.E "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1108.722 0.93 34566 20523 2 1108.721926 555.3683 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 8.75 3805.4 - 485111 - - - -0.0505 - 2.519 0.438 - 302.6 1 2 0 -0.0001 11 0 0 0 3.45E+06 3.69E+06 - - - 4.7753 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20526.20526.2 0.00122 16-Aug R.LVFGFLNGR.A "sp|P00491|PNPH_HUMAN,tr|G3V2H3|G3V2H3_HUMAN,tr|G3V5M2|G3V5M2_HUMAN" 3 1021.5709 3.82 34569 20526 2 1021.573971 511.7927 Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2 9.75 3805.8 - 396736 - - - 3.0052 - 1.531 0.47 - 240.7 1 2 0 0.0031 9 0 0 0 4.65E+06 1.22E+06 - - - 3.7437 1 230117_WJC_METTL3_WT_vs_EV_F04.20527.20527.2 4.51E-06 26-Oct K.VTVNPGLLVPLDVK.L sp|Q6KB66|K2C80_HUMAN 1 1462.8759 -1 34570 20527 2 1462.879076 732.4452 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 5.81 3806 - 372563 - - - 2.1601 - 2.305 0.532 - 236.1 1 2 0 0.0032 14 0 0 0 0.00E+00 0.00E+00 - - - 5.065 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.20534.20534.2 0.00123 16-Sep R.FTGLESIFR[166.11].A sp|Q8N4Q0|PTGR3_HUMAN 1 1078.5687 0.84 34575 20534 2 1078.566931 540.2916 Prostaglandin reductase 3 OS=Homo sapiens OX=9606 GN=ZADH2 PE=1 SV=1 6 3806.9 - 2.42E+06 - - - -1.6077 - 1.66 0.477 - 235.9 1 2 0 -0.0017 9 0 0 0 3.56E+07 4.23E+07 - - - 4.0298 1 230117_WJC_METTL3_WT_vs_EV_F04.20535.20535.2 0.00302 18-Dec K.MAEMLVELVR.R sp|Q9Y605|MOFA1_HUMAN 1 1189.6199 1.13 34576 20535 2 1189.618656 595.8172 MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1 4.53 3807 - 1.70E+06 - - - -1.0466 - 2.578 0.494 - 908.3 1 2 0 -0.0012 10 0 0 0 1.88E+07 1.67E+07 - - - 5.3327 1 230117_WJC_METTL3_WT_vs_EV_F04.20536.20536.2 2.12E-05 16-Aug K.C[160.03]MPTFQFFK.K sp|P10599|THIO_HUMAN 1 1204.5409 2.7 34577 20536 2 1204.541094 603.2777 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3807 - 3.55E+06 - - - 0.142 - 1.837 0.58 - 135.4 1 2 0 0.0002 9 0 0 0 3.45E+07 1.28E+07 - - - 5.0842 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20537.20537.2 4.62E-05 16-Aug K.C[160.03]MPTFQFFK[136.11].K sp|P10599|THIO_HUMAN 1 1212.5551 2.71 34578 20537 2 1212.555587 607.2848 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3807.1 - 1.48E+06 - - - 0.3827 - 1.572 0.482 - 139.7 1 2 0 0.0005 9 0 0 0 3.44E+07 1.27E+07 - - - 3.9096 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.20539.20539.2 0.00146 18-Sep R.IYLDMLNVYK.C "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 11 1270.6631 1.54 34580 20539 2 1270.660838 636.3388 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.83 3807.2 - 845574 - - - -1.8164 - 1.845 0.418 - 233.4 1 2 0 -0.0023 10 0 0 0 1.61E+07 1.04E+07 - - - 3.8372 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.20540.20540.2 0.0445 18-Aug R.IYLDMLNVYK[136.11].C "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 11 1278.6773 3.09 34581 20540 2 1278.68089 640.3459 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.83 3807.3 - 461964 - - - 2.7716 - 1.698 0.34 - 167.3 1 2 0 0.0035 10 0 0 0 3.22E+07 1.04E+07 - - - 3.029 0.8918 230117_WJC_METTL3_WT_vs_EV_F04.20541.20541.2 2.16 12-Jun K.DLVEWLK.L "sp|Q9P2D1|CHD7_HUMAN,sp|Q14554|PDIA5_HUMAN" 2 901.4909 2.36 34582 20541 2 901.48914 451.7527 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.37 3807.4 - 327893 - - - -1.9734 - 1.132 0.063 - 140.7 1 2 0 -0.0018 7 0 0 0 4.68E+06 1.98E+06 - - - -0.1014 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.20543.20543.2 0.04 16-Aug R.LVFGFLNGR[166.11].A "sp|P00491|PNPH_HUMAN,tr|G3V2H3|G3V2H3_HUMAN,tr|G3V5M2|G3V5M2_HUMAN" 3 1031.5792 3.82 34584 20543 2 1031.5783 516.7969 Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2 9.75 3807.7 - 193503 - - - -0.8443 - 1.553 0.336 - 137.8 1 2 0 -0.0009 9 0 0 0 4.65E+06 1.22E+06 - - - 2.7959 0.9909 230117_WJC_METTL3_WT_vs_EV_F04.20546.20546.2 0.258 18-Apr K.DSPFGLSFVR[166.11].F "sp|P18887|XRCC1_HUMAN,tr|M0R1U8|M0R1U8_HUMAN,tr|M0R0D2|M0R0D2_HUMAN,tr|M0QYS5|M0QYS5_HUMAN,tr|F5H8D7|F5H8D7_HUMAN,tr|M0QZ96|M0QZ96_HUMAN" 6 1133.5745 1.8 34587 20546 2 1133.574274 567.7945 DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2 5.84 3808.1 - 220712 - - - -0.1808 - 1.108 0.254 - 42.7 5 2 0 -0.0002 10 0 0 0 2.90E+06 1.61E+06 - - - 0.891 1 230117_WJC_METTL3_WT_vs_EV_F04.20547.20547.2 0.0173 14/22 R.VIQELLVDYYVK.L "sp|Q9H6D7|HAUS4_HUMAN,tr|H0YJ09|H0YJ09_HUMAN,tr|G3V4X7|G3V4X7_HUMAN,tr|G3V5A5|G3V5A5_HUMAN,tr|G3V541|G3V541_HUMAN,tr|H0YIZ6|H0YIZ6_HUMAN,tr|G3V5Z2|G3V5Z2_HUMAN" 7 1480.8177 -1 34588 20547 2 1480.813397 741.4161 HAUS augmin-like complex subunit 4 OS=Homo sapiens OX=9606 GN=HAUS4 PE=1 SV=1 4.37 3808.2 - 0 - - - -2.9281 - 2.73 0.408 - 742.1 1 2 0 -0.0043 12 0 0 0 0.00E+00 0.00E+00 - - - 4.6956 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.20552.20552.2 0.195 14-Aug K.DTLGLFLR.E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 933.5284 1.49 34591 20552 2 933.529319 467.7715 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.84 3808.8 - 2.49E+06 - - - 1.0198 - 1.73 0.147 - 266.9 1 2 0 0.001 8 0 0 0 7.63E+07 5.12E+07 - - - 1.7796 1 230117_WJC_METTL3_WT_vs_EV_F04.20560.20560.2 1.05E-06 20-Oct K.YFFFDDGNGLK.G sp|P61009|SPCS3_HUMAN 1 1321.5979 0.95 34599 20560 2 1321.598651 661.8062 Signal peptidase complex subunit 3 OS=Homo sapiens OX=9606 GN=SPCS3 PE=1 SV=1 4.21 3809.6 - 334082 - - - 0.566 - 1.77 0.604 - 279.1 1 2 0 0.0007 11 0 0 0 3.50E+06 3.69E+06 - - - 5.0465 1 230117_WJC_METTL3_WT_vs_EV_F04.20562.20562.2 1.92E-07 16/24 K.ILESSQTLLSVLK.R "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1429.8392 3.18 34601 20562 2 1429.839206 715.9269 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 6 3809.9 - 249758 - - - 0.007 - 2.793 0.596 - 622.6 1 2 0 0 13 0 0 0 2.09E+07 6.58E+06 - - - 6.0792 1 230117_WJC_METTL3_WT_vs_EV_F04.20564.20564.2 6.16E-06 14/22 K.IGLIQFC[160.03]LSAPK.T sp|P50991|TCPD_HUMAN 1 1345.7428 9.41 34603 20564 2 1345.741899 673.8787 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3810.2 - 203842 - - - -0.6651 - 2.607 0.521 - 734.5 1 2 0 -0.0009 12 0 0 0 1.58E+08 1.68E+07 - - - 5.41 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.20565.20565.2 0.000647 18-Nov K.IMLPWDPTGK[136.11].L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1164.6093 1.79 34604 20565 2 1164.607129 583.3119 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3810.3 - 192722 - - - -1.835 - 1.866 0.397 - 408.7 1 2 0 -0.0021 10 0 0 0 8.08E+07 4.51E+07 - - - 3.7138 1 230117_WJC_METTL3_WT_vs_EV_F04.20573.20573.2 4.09E-05 14/22 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 3819.87 34611 20573 2 1603.765431 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3811.3 - 6.38E+08 - - - 0.9297 - 2.099 0.531 - 561.5 1 2 0 0.0015 12 0 0 0 3.08E+09 8.06E+05 - - - 4.9134 1 230117_WJC_METTL3_WT_vs_EV_F04.20575.20575.2 1.60E-14 17/30 R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 18.6 34613 20575 2 1756.900075 879.4608 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3811.5 - 2.04E+07 - - - -3.9177 - 3.663 0.599 - 1160.9 1 2 0 -0.0069 16 0 0 0 5.63E+07 3.03E+06 - - - 6.6549 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.20576.20576.3 1.07E-05 15/60 R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 13.65 34614 20576 3 1756.9044 586.6429 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3811.6 - 9.36E+06 - - - -1.456 - 2.668 0.533 - 356.8 1 2 0 -0.0026 16 0 0 0 3.07E+07 2.25E+06 - - - 6.9997 1 230117_WJC_METTL3_WT_vs_EV_F04.20578.20578.2 1.13E-10 18/28 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.26 34616 20578 2 1548.923543 775.4692 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3811.8 - 6.74E+06 - - - -0.2492 - 3.694 0.634 - 698.3 1 2 0 -0.0004 15 0 0 0 7.23E+07 5.74E+07 - - - 6.9362 1 230117_WJC_METTL3_WT_vs_EV_F04.20579.20579.2 4.38E-08 19/28 K.LLGASELPIVTPALR[166.11].A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1558.9322 1.26 34617 20579 2 1558.932327 780.4734 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3811.9 - 4.96E+06 - - - 0.0821 - 3.494 0.549 - 778.5 1 2 0 0.0001 15 0 0 0 7.63E+07 6.06E+07 - - - 6.1716 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.20580.20580.2 0.00339 18-Sep K.DLIGVQNLLK[136.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1119.6743 1.02 34618 20580 2 1119.671357 560.8444 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3812 - 4.60E+06 - - - -2.6374 - 2.006 0.403 - 209.9 1 2 0 -0.003 10 0 0 0 1.50E+07 1.47E+07 - - - 3.9598 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.20581.20581.2 0.0099 18-Sep K.DLIGVQNLLK.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1111.6601 0.93 34619 20581 2 1111.658006 556.8373 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3812.1 - 4.37E+06 - - - -1.8927 - 1.853 0.322 - 207.6 1 2 0 -0.0021 10 0 0 0 1.37E+07 1.47E+07 - - - 3.1403 0.998 230117_WJC_METTL3_WT_vs_EV_F04.20583.20583.2 0.00315 18-Nov K.IMLPWDPTGK.L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1156.5951 1.78 34621 20583 2 1156.592316 579.3048 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3812.3 - 3.27E+06 - - - -2.3777 - 1.773 0.468 - 459.7 1 2 0 -0.0028 10 0 0 0 8.03E+07 4.51E+07 - - - 4.0953 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.20585.20585.2 4.27E-05 18-Aug R.AFDLFNPNFK.S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1211.5975 1.57 34623 20585 2 1211.594647 606.806 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3812.5 - 2.33E+06 - - - -2.3622 - 1.843 0.5 - 157.4 1 2 0 -0.0029 10 0 0 0 3.74E+07 2.38E+07 - - - 4.4397 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.20586.20586.2 0.051 12-Oct R.EIALWFR[166.11].A "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 943.5155 1.31 34624 20586 2 943.51381 472.765 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6.1 3812.6 - 2.01E+06 - - - -1.7997 - 1.955 0.36 - 487.3 1 2 0 -0.0017 7 0 0 0 1.48E+07 1.13E+07 - - - 3.8236 1 230117_WJC_METTL3_WT_vs_EV_F04.20587.20587.2 4.85E-12 16/30 R.LMNETTAVALAYGIYK[136.11].Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1764.9212 18.6 34625 20587 2 1764.914562 883.4679 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3812.7 - 1.98E+06 - - - -3.7373 - 3.514 0.612 - 916.2 1 2 0 -0.0066 16 0 0 0 5.63E+07 3.03E+06 - - - 6.649 1 230117_WJC_METTL3_WT_vs_EV_F04.20588.20588.2 3.92E-05 18-Oct R.AFDLFNPNFK[136.11].S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1219.6117 1.57 34626 20588 2 1219.608809 610.8131 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3812.9 - 1.94E+06 - - - -2.3778 - 1.928 0.55 - 289.7 1 2 0 -0.0029 10 0 0 0 3.74E+07 2.38E+07 - - - 4.9348 1 230117_WJC_METTL3_WT_vs_EV_F04.20590.20590.2 1.14E-05 22-Dec K.IGLIQFC[160.03]LSAPK[136.11].T sp|P50991|TCPD_HUMAN 1 1353.757 9.4 34628 20590 2 1353.757985 677.8858 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3813.1 - 1.86E+06 - - - 0.732 - 2.765 0.476 - 515.3 1 2 0 0.001 12 0 0 0 1.58E+08 1.68E+07 - - - 5.2324 0.9786 230117_WJC_METTL3_WT_vs_EV_F04.20592.20592.2 0.357 18-Oct K.QLLLIAGLTR.E "sp|Q9UJX2|CDC23_HUMAN,tr|D6RCF8|D6RCF8_HUMAN,tr|D6RBY8|D6RBY8_HUMAN,tr|H0Y936|H0Y936_HUMAN" 4 1096.6968 1.01 34630 20592 2 1096.693685 549.3557 Cell division cycle protein 23 homolog OS=Homo sapiens OX=9606 GN=CDC23 PE=1 SV=3 9.75 3813.4 - 1.43E+06 - - - -2.8668 - 2.037 0.07 - 277.4 1 2 0 -0.0031 10 0 0 0 8.20E+06 8.11E+06 - - - 1.543 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.20594.20594.3 0.000847 Jun-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 34631 20594 3 1603.762551 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3813.6 - 5.86E+06 - - - -0.8661 - 1.364 0.42 - 65.5 1 2 0 -0.0014 12 0 0 0 2.24E+08 0.00E+00 - - - 4.0826 1 230117_WJC_METTL3_WT_vs_EV_F04.20595.20595.2 0.0128 14/22 K.EALQLMATYLPK.D "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 13 1376.7374 2.42 34632 20595 2 1376.734316 689.376 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 6.1 3813.7 - 169955 - - - -2.2212 - 2.503 0.44 - 575.8 1 2 0 -0.0031 12 0 0 0 7.58E+07 3.13E+07 - - - 4.704 1 230117_WJC_METTL3_WT_vs_EV_F04.20597.20597.2 4.55E-05 22-Oct K.GIDPFSLDALSK[136.11].E sp|P40227|TCPZ_HUMAN 1 1269.6696 9.9 34634 20597 2 1269.669845 635.8421 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3813.9 - 261779 - - - 0.1788 - 2.3 0.512 - 286.5 1 2 0 0.0002 12 0 0 0 5.10E+08 5.15E+07 - - - 5.0141 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20598.20598.2 0.0028 14-Aug K.FGFYEVFK[136.11].V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1043.5208 0.95 34635 20598 2 1043.521319 522.7677 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3813.9 - 225205 - - - 0.5271 - 1.578 0.412 - 133.8 1 2 0 0.0006 8 0 0 0 3.89E+07 4.11E+07 - - - 3.4596 0.985 230117_WJC_METTL3_WT_vs_EV_F04.20602.20602.2 0.456 14-Jul R.ETILNLLR[166.11].K "sp|Q6P158|DHX57_HUMAN,tr|A0A087WZ11|A0A087WZ11_HUMAN" 2 980.5894 0.88 34639 20602 2 980.585975 491.302 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 6.1 3814.4 - 59437.7 - - - -3.4938 - 1.72 0.211 - 178.8 1 2 0 -0.0034 8 0 0 0 8.92E+06 1.01E+07 - - - 2.234 0.9553 230117_WJC_METTL3_WT_vs_EV_F04.20605.20605.2 1.19 18-Apr K.ILDVLEEIPK.N "sp|Q16718|NDUA5_HUMAN,tr|C9IZN5|C9IZN5_HUMAN,tr|H7BYD0|H7BYD0_HUMAN,tr|A0A087X1G1|A0A087X1G1_HUMAN,tr|F8WAS3|F8WAS3_HUMAN,tr|A0A7I2V2W4|A0A7I2V2W4_HUMAN,tr|A0A7I2V3L8|A0A7I2V3L8_HUMAN" 7 1167.6751 2.22 34640 20605 2 1167.675194 584.8448 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3 4.14 3814.8 - 5.21E+06 - - - 0.0882 - 0.862 0.144 - 36.4 1 2 0 0.0001 10 0 0 0 7.62E+07 3.43E+07 - - - -0.31 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20608.20608.2 0.0224 14-Sep K.FGFYEVFK.V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1035.5066 0.95 34643 20608 2 1035.506546 518.7606 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3815 - 3.04E+06 - - - -0.0222 - 1.755 0.358 - 184.7 1 2 0 0 8 0 0 0 3.89E+07 4.11E+07 - - - 3.3816 1 230117_WJC_METTL3_WT_vs_EV_F04.20609.20609.2 0.2 22-Oct R.VPFLVLEC[160.03]PNLK.L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1427.7847 0.97 34644 20609 2 1427.788199 714.8996 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3815 - 2.37E+06 - - - 2.4801 - 2.376 0.461 - 477.8 1 2 0 0.0035 12 0 0 0 1.67E+07 1.73E+07 - - - 4.7219 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.20610.20610.2 0.0661 16-Sep R.NALDLLLPK.L "sp|P30566|PUR8_HUMAN,tr|A0A096LNY5|A0A096LNY5_HUMAN,tr|A0A1B0GTJ7|A0A1B0GTJ7_HUMAN,tr|A0A1B0GWJ0|A0A1B0GWJ0_HUMAN,tr|A0A1B0GWF8|A0A1B0GWF8_HUMAN,tr|A0A096LNY4|A0A096LNY4_HUMAN,tr|A0A1B0GTG9|A0A1B0GTG9_HUMAN,tr|A0A7P0T9A7|A0A7P0T9A7_HUMAN,tr|A0A096LNY6|A0A096LNY6_HUMAN,tr|A0A096LP92|A0A096LP92_HUMAN,tr|A0A7P0Z472|A0A7P0Z472_HUMAN" 11 995.6015 1.43 34645 20610 2 995.603798 498.808 Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2 5.84 3815.1 - 1.29E+06 - - - 2.276 - 1.53 0.216 - 286.5 1 2 0 0.0023 9 0 0 0 2.10E+07 1.48E+07 - - - 1.866 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.20614.20614.2 0.0104 18-Sep R.LGGIAYFLSR[166.11].L "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1105.616 1.05 34647 20614 2 1105.614898 553.8153 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 8.75 3815.6 - 2.54E+06 - - - -0.9515 - 1.873 0.352 - 246.1 1 2 0 -0.0011 10 0 0 0 1.99E+07 1.90E+07 - - - 3.3922 1 230117_WJC_METTL3_WT_vs_EV_F04.20615.20615.2 7.67E-05 15/22 R.VPFLVLEC[160.03]PNLK[136.11].L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1435.7989 0.97 34648 20615 2 1435.796781 718.9067 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3815.7 - 2.00E+06 - - - -1.4466 - 2.401 0.511 - 657.9 1 2 0 -0.0021 12 0 0 0 1.67E+07 1.73E+07 - - - 5.1192 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.20617.20617.2 0.00267 22-Aug K.LVGQSIIAYLQK.K "sp|P53621|COPA_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 3 1331.7813 2 34650 20617 2 1331.779732 666.8979 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 8.59 3816 - 1.14E+06 - - - -1.1676 - 1.734 0.377 - 164.3 1 2 0 -0.0016 12 0 0 0 8.80E+06 4.39E+06 - - - 3.2733 0.9838 230117_WJC_METTL3_WT_vs_EV_F04.20618.20618.2 0.0379 16-Sep R.NALDLLLPK[136.11].L "sp|P30566|PUR8_HUMAN,tr|A0A096LNY5|A0A096LNY5_HUMAN,tr|A0A1B0GTJ7|A0A1B0GTJ7_HUMAN,tr|A0A1B0GWJ0|A0A1B0GWJ0_HUMAN,tr|A0A1B0GWF8|A0A1B0GWF8_HUMAN,tr|A0A096LNY4|A0A096LNY4_HUMAN,tr|A0A1B0GTG9|A0A1B0GTG9_HUMAN,tr|A0A7P0T9A7|A0A7P0T9A7_HUMAN,tr|A0A096LNY6|A0A096LNY6_HUMAN,tr|A0A096LP92|A0A096LP92_HUMAN,tr|A0A7P0Z472|A0A7P0Z472_HUMAN" 11 1003.6157 1.43 34651 20618 2 1003.614666 502.8151 Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2 5.84 3816.1 - 1.12E+06 - - - -1.0622 - 1.437 0.105 - 197.8 1 2 0 -0.0011 9 0 0 0 2.10E+07 1.48E+07 - - - 0.8651 0.9943 230117_WJC_METTL3_WT_vs_EV_F04.20619.20619.2 6.32E-06 18-Nov K.FSDFLLDPYK[136.11].Y sp|Q9UIG0|BAZ1B_HUMAN 1 1251.6267 0.78 34652 20619 2 1251.633841 626.8206 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 4.21 3816.3 - 1.12E+06 - - - 5.7126 - 2.189 0.268 - 329.6 1 2 0 0.0072 10 0 0 0 1.10E+07 1.41E+07 - - - 3.205 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.20624.20624.2 0.0154 16-Aug R.FVC[160.03]PVILFK.G "sp|Q8NCE2|MTMRE_HUMAN,tr|B4DJ23|B4DJ23_HUMAN" 2 1121.6307 0.67 34657 20624 2 1121.630711 561.8226 Myotubularin-related protein 14 OS=Homo sapiens OX=9606 GN=MTMR14 PE=1 SV=2 8.22 3816.9 - 653636 - - - -0.0116 - 1.464 0.352 - 155.2 1 2 0 0 9 0 0 0 7.24E+06 1.09E+07 - - - 2.7436 0.9965 230117_WJC_METTL3_WT_vs_EV_F04.20626.20626.2 0.000867 16-Aug R.QVLLEIFSK.N "sp|Q9NVU0|RPC5_HUMAN,tr|A0A0C4DH01|A0A0C4DH01_HUMAN" 2 1075.6277 1.44 34659 20626 2 1075.624659 538.8211 DNA-directed RNA polymerase III subunit RPC5 OS=Homo sapiens OX=9606 GN=POLR3E PE=1 SV=1 6 3817.2 - 601474 - - - -2.8709 - 1.75 0.394 - 165.2 1 2 0 -0.0031 9 0 0 0 4.81E+06 3.34E+06 - - - 3.5691 0.9428 230117_WJC_METTL3_WT_vs_EV_F04.20632.20632.3 3.81E-06 Oct-36 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 34665 20632 3 1343.60977 448.8778 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3818 - 374623 - - - -1.2593 - 1.71 0.544 - 200.2 1 1 0 -0.0017 10 0 0 0 1.07E+06 0.00E+00 - - - 6.1714 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20636.20636.2 0.0128 16-Nov K.TEILPPFFK[136.11].H sp|O75533|SF3B1_HUMAN 1 1098.6205 1.02 34668 20636 2 1098.621149 550.3175 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.66 3818.4 - 942341 - - - 0.6062 - 2.037 0.343 - 495.5 1 2 0 0.0007 9 0 0 0 5.63E+07 5.53E+07 - - - 3.6325 1 230117_WJC_METTL3_WT_vs_EV_F04.20638.20638.2 0.000462 20-Dec K.WYLENVYPELR.V sp|Q10471|GALT2_HUMAN 1 1480.7351 1.08 34670 20638 2 1480.738786 741.3748 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3818.6 - 808558 - - - 2.5129 - 2.321 0.489 - 588.4 1 2 0 0.0037 11 0 0 0 3.59E+07 3.33E+07 - - - 4.9294 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.20639.20639.2 0.249 16-Aug K.TEILPPFFK.H sp|O75533|SF3B1_HUMAN 1 1090.6063 1.02 34671 20639 2 1090.606969 546.3104 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.66 3818.6 - 655348 - - - 0.629 - 1.401 0.237 - 268.4 1 2 0 0.0007 9 0 0 0 5.63E+07 5.53E+07 - - - 1.7668 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20641.20641.2 0.000772 20-Oct K.FLFVDADQIVR.T sp|Q9NYU2|UGGG1_HUMAN 1 1321.703 7.86 34673 20641 2 1321.706674 661.8588 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.21 3818.9 - 491034 - - - 2.7518 - 1.959 0.434 - 266 1 2 0 0.0036 11 0 0 0 4.44E+07 5.66E+06 - - - 4.0645 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20643.20643.2 0.000111 16-Oct R.FYNLVLLPR.V "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1133.6597 1.04 34675 20643 2 1133.659332 567.8371 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 3819.1 - 366770 - - - -0.3387 - 2.009 0.434 - 428.4 1 2 0 -0.0004 9 0 0 0 3.86E+07 3.72E+07 - - - 4.2647 1 230117_WJC_METTL3_WT_vs_EV_F04.20644.20644.2 0.0025 20-Nov K.ILLTQENPFFR[166.11].K sp|Q08J23|NSUN2_HUMAN 1 1386.7535 2.39 34676 20644 2 1386.757388 694.384 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3819.2 - 355783 - - - 2.7993 - 2.384 0.494 - 439.6 1 2 0 0.0039 11 0 0 0 7.34E+07 3.07E+07 - - - 5.0387 0.9922 230117_WJC_METTL3_WT_vs_EV_F04.20652.20652.2 0.292 16-Jun K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 2871.97 34682 20652 2 1014.538749 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3820.2 - 4.28E+06 - - - 4.1142 - 1.424 0.22 - 86 1 2 0 0.0042 9 0 0 0 3.50E+08 1.22E+05 - - - 1.6872 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20653.20653.2 0.000158 20-Nov K.IFGVTTLDIVR.A "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1232.7129 1.16 34683 20653 2 1232.715925 617.3637 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 5.84 3820.2 - 799875 - - - 2.4758 - 2.201 0.325 - 446.8 1 2 0 0.0031 11 0 0 0 3.15E+07 2.72E+07 - - - 3.5747 1 230117_WJC_METTL3_WT_vs_EV_F04.20655.20655.2 8.57E-08 18/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 34685 20655 2 1343.611225 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3820.5 - 719552 - - - -0.1764 - 2.995 0.544 - 1275.8 1 1 0 -0.0002 10 0 0 0 2.08E+07 0.00E+00 - - - 6.1208 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20656.20656.2 6.76E-05 20-Dec R.NTISLLVAGLK.K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1127.6914 1.57 34686 20656 2 1127.691413 564.853 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.75 3820.6 - 121796 - - - 0.0027 - 2.389 0.413 - 530.7 1 2 0 0 11 0 0 0 1.33E+07 8.49E+06 - - - 4.4473 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.20657.20657.2 0.000303 18-Oct K.FSDFLLDPYK.Y sp|Q9UIG0|BAZ1B_HUMAN 1 1243.6125 0.78 34687 20657 2 1243.617125 622.8135 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 4.21 3820.7 - 254166 - - - 3.7262 - 1.335 0.427 - 198 1 2 0 0.0046 10 0 0 0 1.10E+07 1.41E+07 - - - 2.9999 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20658.20658.2 0.00051 14-Oct K.TFFLEALR.G "sp|Q9H0R4|HDHD2_HUMAN,tr|K7ER15|K7ER15_HUMAN" 2 995.544 1.59 34688 20658 2 995.544247 498.7793 Haloacid dehalogenase-like hydrolase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=HDHD2 PE=1 SV=1 5.66 3820.9 - 235162 - - - 0.231 - 1.77 0.464 - 376.5 1 2 0 0.0002 8 0 0 0 6.30E+06 3.96E+06 - - - 4.1901 1 230117_WJC_METTL3_WT_vs_EV_F04.20661.20661.2 0.00293 20-Dec M.LAVDAVIAELK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1148.6896 2.57 34691 20661 2 1148.688512 575.3521 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.37 3821.3 - 87607.5 - - - -0.9689 - 2.604 0.453 - 319.2 1 1 0 -0.0011 11 0 0 0 1.08E+07 4.21E+06 - - - 4.9756 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20662.20662.2 0.000761 18-Nov K.YSDIDIILLK[136.11].G "sp|Q92973|TNPO1_HUMAN,tr|A0A7P0T9C0|A0A7P0T9C0_HUMAN,tr|A0A7P0TBF0|A0A7P0TBF0_HUMAN,tr|A0A7P0T944|A0A7P0T944_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 5 1199.6893 0.81 34692 20662 2 1199.690456 600.8519 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 4.21 3821.4 - 188529 - - - 0.9711 - 1.936 0.424 - 206.3 1 2 0 0.0012 10 0 0 0 1.32E+07 1.62E+07 - - - 4.0163 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20663.20663.2 0.00383 14-Sep K.DLEDLFYK[136.11].Y "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1049.5161 1.03 34693 20663 2 1049.517694 525.7653 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.03 3821.5 - 131573 - - - 1.5398 - 1.795 0.466 - 265.2 1 2 0 0.0016 8 0 0 0 7.36E+06 7.17E+06 - - - 4.2467 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.20667.20667.3 6.08E-05 Nov-56 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 535.22 34695 20667 3 1658.90961 553.977 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3822.1 - 9.86E+06 - - - 0.3273 - 2.335 0.432 - 200.9 1 2 0 0.0005 15 0 0 0 1.28E+08 2.39E+05 - - - 5.569 1 230117_WJC_METTL3_WT_vs_EV_F04.20668.20668.2 0.000175 28-Oct K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 425.74 34696 20668 2 1658.906399 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3822.1 - 7.47E+06 - - - -1.6083 - 2.29 0.505 - 398.8 1 2 0 -0.0027 15 0 0 0 1.56E+08 3.67E+05 - - - 4.8071 1 230117_WJC_METTL3_WT_vs_EV_F04.20669.20669.2 1.70E-05 20-Nov K.LFTAESLIGLK.N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1190.6911 1.86 34697 20669 2 1190.692134 596.3528 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6 3822.2 - 4.23E+06 - - - 0.8894 - 2.224 0.511 - 371.4 1 2 0 0.0011 11 0 0 0 3.49E+07 1.88E+07 - - - 4.9772 0.9584 230117_WJC_METTL3_WT_vs_EV_F04.20670.20670.2 0.00038 20-Sep K.LTPLILK[136.11]PFGN.S "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1219.742 1.1 34698 20670 2 1219.742641 610.8783 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 8.75 3822.2 - 1.81E+06 - - - 0.5296 - 1.585 0.409 - 238.5 1 1 0 0.0006 11 0 0 0 1.94E+07 1.76E+07 - - - 3.3077 1 230117_WJC_METTL3_WT_vs_EV_F04.20671.20671.2 4.35E-07 14/22 R.VPDGMVGLIIGR.G "sp|Q92945|FUBP2_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 1225.6853 2.68 34699 20671 2 1225.688121 613.8499 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.81 3822.3 - 1.44E+06 - - - 2.3195 - 2.543 0.606 - 841.1 1 2 0 0.0028 12 0 0 0 3.09E+07 1.15E+07 - - - 5.9718 1 230117_WJC_METTL3_WT_vs_EV_F04.20672.20672.2 3.03E-07 24-Oct K.ILGVWDTAVSLGK.L sp|Q53RT3|APRV1_HUMAN 1 1357.7606 33.33 34700 20672 2 1357.761635 679.8876 Retroviral-like aspartic protease 1 OS=Homo sapiens OX=9606 GN=ASPRV1 PE=1 SV=1 5.84 3822.3 - 1.35E+06 - - - 0.7976 - 2.336 0.591 - 339.8 1 2 0 0.0011 13 0 0 0 1.25E+07 3.76E+05 - - - 5.5833 0.9604 230117_WJC_METTL3_WT_vs_EV_F04.20673.20673.2 0.00979 20-Oct K.LTPLILKPFGN.S "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1211.7278 1.1 34701 20673 2 1211.728156 606.8712 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 8.75 3822.4 - 1.09E+06 - - - 0.2979 - 1.659 0.423 - 303.2 1 1 0 0.0004 11 0 0 0 1.94E+07 1.76E+07 - - - 3.5346 1 230117_WJC_METTL3_WT_vs_EV_F04.20675.20675.2 4.61E-08 26-Nov K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.15 34703 20675 2 1416.843361 709.4289 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3822.6 - 780645 - - - 0.1376 - 2.502 0.597 - 418.2 1 2 0 0.0002 14 0 0 0 1.60E+08 1.39E+08 - - - 5.7518 1 230117_WJC_METTL3_WT_vs_EV_F04.20676.20676.2 1.91E-08 26-Dec K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.15 34704 20676 2 1408.829131 705.4218 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3822.6 - 755754 - - - 0.1171 - 2.749 0.612 - 592.9 1 2 0 0.0002 14 0 0 0 1.60E+08 1.39E+08 - - - 6.0988 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20678.20678.2 0.000202 14-Jul K.ETLLAMFK.Y sp|P26639|SYTC_HUMAN 1 951.5099 2.21 34706 20678 2 951.510018 476.7622 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 6.1 3822.8 - 334838 - - - 0.082 - 1.449 0.474 - 151.1 1 2 0 0.0001 8 0 0 0 4.16E+06 1.88E+06 - - - 3.6605 0.987 230117_WJC_METTL3_WT_vs_EV_F04.20679.20679.2 3.96 14-Jun R.LPLQDVYK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 974.5437 3.24 34707 20679 2 974.543539 488.2791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 3823 - 0 - - - -0.1478 - 1.248 0.141 - 81.4 2 2 0 -0.0001 8 0 0 0 2.48E+06 7.65E+05 - - - 0.6161 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20682.20682.2 0.000299 16-Sep R.GFAFVYFER[166.11].L sp|Q13595|TRA2A_HUMAN 1 1144.5581 0.9 34708 20682 2 1144.559097 573.2863 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3823.4 - 4.07E+06 - - - 0.8702 - 1.863 0.365 - 319 1 2 0 0.001 9 0 0 0 4.64E+07 5.14E+07 - - - 3.5366 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20683.20683.2 0.119 16-Oct R.GFAFVYFER.L sp|Q13595|TRA2A_HUMAN 1 1134.5498 0.9 34709 20683 2 1134.550647 568.2822 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3823.4 - 3.14E+06 - - - 0.7192 - 1.738 0.352 - 385.9 1 2 0 0.0008 9 0 0 0 4.64E+07 5.14E+07 - - - 3.2397 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20685.20685.2 0.000163 16-Sep R.YLTVAAIFR.G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1052.6019 2.96 34711 20685 2 1052.602178 527.3082 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3823.7 - 1.27E+06 - - - 0.2964 - 1.965 0.423 - 284.1 1 2 0 0.0003 9 0 0 0 2.68E+07 9.03E+06 - - - 4.1194 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.20686.20686.3 1.31E-07 15/56 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.28 34712 20686 3 1548.924015 517.3153 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3823.8 - 747277 - - - 0.0555 - 2.71 0.511 - 275 1 2 0 0.0001 15 0 0 0 1.74E+07 1.36E+07 - - - 6.8385 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.20689.20689.3 1.07E-05 13/52 K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.28 34715 20689 3 1408.828421 470.6169 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3824.2 - 403366 - - - -0.3868 - 2.642 0.522 - 217.7 1 2 0 -0.0005 14 0 0 0 3.00E+07 2.35E+07 - - - 6.9415 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20691.20691.2 0.000477 22-Jun R.IFGDNFDPDFIK[136.11].Q "sp|Q96BR1|SGK3_HUMAN,tr|E5RJV7|E5RJV7_HUMAN,tr|E5RK28|E5RK28_HUMAN,tr|E5RHY6|E5RHY6_HUMAN,tr|E5RHX2|E5RHX2_HUMAN" 5 1434.6911 0.94 34717 20691 2 1434.694295 718.3528 Serine\threonine-protein kinase Sgk3 OS=Homo sapiens OX=9606 GN=SGK3 PE=1 SV=1 3.93 3824.5 - 350182 - - - 2.2395 - 1.497 0.409 - 53.2 1 2 0 0.0032 12 0 0 0 1.33E+06 1.42E+06 - - - 3.1224 0.999 230117_WJC_METTL3_WT_vs_EV_F04.20692.20692.2 0.129 22-Aug R.LTVLLPLAAAER[166.11].D sp|Q8IZ52|CHSS2_HUMAN 1 1275.779 1.93 34718 20692 2 1275.778699 638.8968 Chondroitin sulfate synthase 2 OS=Homo sapiens OX=9606 GN=CHPF PE=1 SV=2 6 3824.6 - 347344 - - - -0.2304 - 1.87 0.303 - 170.9 1 2 0 -0.0003 12 0 0 0 3.20E+06 1.65E+06 - - - 2.9258 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.20693.20693.2 0.0426 22-Oct K.ALLVEVQLLESK[136.11].T sp|O00231|PSD11_HUMAN 1 1348.8057 1.89 34719 20693 2 1348.805581 675.4101 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.53 3824.7 - 322392 - - - -0.1016 - 2.14 0.275 - 297.3 1 2 0 -0.0001 12 0 0 0 5.29E+06 2.80E+06 - - - 3.0739 1 230117_WJC_METTL3_WT_vs_EV_F04.20694.20694.2 1.94E-05 22-Nov R.YGLFPANYVELR[166.11].Q sp|Q14247|SRC8_HUMAN 1 1450.7484 1.95 34720 20694 2 1450.747427 726.3815 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 6 3824.9 - 301286 - - - -0.6852 - 2.323 0.52 - 284.3 1 2 0 -0.001 12 0 0 0 1.19E+07 6.13E+06 - - - 5.0991 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.20695.20695.2 0.181 14-Jul R.VIFGLFGK.T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 879.5218 0.62 34721 20695 2 879.520843 440.7682 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.72 3825 - 274980 - - - -1.1165 - 1.453 0.318 - 133.4 1 2 0 -0.001 8 0 0 0 2.76E+07 4.45E+07 - - - 2.5163 0.9346 230117_WJC_METTL3_WT_vs_EV_F04.20696.20696.2 5.48 16-Jul K.TSVVGLFLR.H "sp|Q9UJX4|APC5_HUMAN,tr|F5GY68|F5GY68_HUMAN,tr|F5H0F9|F5H0F9_HUMAN,tr|F5GZ05|F5GZ05_HUMAN,tr|F5H3S5|F5H3S5_HUMAN" 5 990.5862 0.4 34722 20696 2 990.588962 496.3004 Anaphase-promoting complex subunit 5 OS=Homo sapiens OX=9606 GN=ANAPC5 PE=1 SV=2 9.41 3825.1 - 249697 - - - 2.7721 - 0.912 0.101 - 86.6 1 2 0 0.0027 9 0 0 0 1.68E+06 4.19E+06 - - - -0.4804 1 230117_WJC_METTL3_WT_vs_EV_F04.20700.20700.2 1.41E-06 18-Nov K.EFVEAVLELR.K "sp|O75367|H2AY_HUMAN,tr|B4DJC3|B4DJC3_HUMAN" 2 1203.6499 0.88 34726 20700 2 1203.652084 602.8322 Core histone macro-H2A.1 OS=Homo sapiens OX=9606 GN=MACROH2A1 PE=1 SV=4 4.25 3825.6 - 339377 - - - 1.7821 - 2.244 0.493 - 573.3 1 2 0 0.0021 10 0 0 0 7.90E+06 8.94E+06 - - - 4.9377 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20703.20703.2 0.00119 24-Nov R.GAVGALLVYDIAK[136.11].H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1296.7533 1.47 34728 20703 2 1296.752233 649.3839 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3826.1 - 341037 - - - -0.8136 - 2.351 0.419 - 407.5 1 2 0 -0.0011 13 0 0 0 8.21E+07 5.58E+07 - - - 4.3294 1 230117_WJC_METTL3_WT_vs_EV_F04.20707.20707.2 2.48E-07 17/34 K.ILDSFAAAPVPTTTLVLK.S sp|P18583|SON_HUMAN 1 1856.0659 1.47 34732 20707 2 1856.068833 929.0402 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3826.5 - 1.62E+06 - - - 1.5791 - 3.197 0.593 - 558.8 1 2 0 0.0029 18 0 0 0 1.55E+07 1.05E+07 - - - 6.2773 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20708.20708.2 0.00384 16-Sep R.YLTVAAIFR[166.11].G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1062.6101 2.97 34733 20708 2 1062.611373 532.3123 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3826.5 - 1.39E+06 - - - 1.1641 - 1.999 0.419 - 289.4 1 2 0 0.0012 9 0 0 0 2.70E+07 9.09E+06 - - - 4.1392 1 230117_WJC_METTL3_WT_vs_EV_F04.20712.20712.2 6.45E-07 20-Oct R.GGYFDEFGIIR.D "sp|P11413|G6PD_HUMAN,tr|E7EM57|E7EM57_HUMAN,tr|E7EUI8|E7EUI8_HUMAN" 3 1272.6139 3.96 34737 20712 2 1272.611977 637.3142 Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4 4.37 3827 - 508661 - - - -1.5016 - 1.762 0.568 - 234.2 1 2 0 -0.0019 11 0 0 0 5.53E+06 1.40E+06 - - - 4.768 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.20715.20715.2 0.000423 22-Sep K.GIDPFSLDALSK.E sp|P40227|TCPZ_HUMAN 1 1261.6554 9.9 34739 20715 2 1261.654958 631.835 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3827.3 - 778546 - - - -0.3646 - 1.615 0.474 - 235.5 1 2 0 -0.0005 12 0 0 0 5.10E+08 5.15E+07 - - - 3.803 1 230117_WJC_METTL3_WT_vs_EV_F04.20719.20719.2 4.09E-10 20/34 K.ILDSFAAAPVPTTTLVLK[136.11].S sp|P18583|SON_HUMAN 1 1864.0801 1.47 34742 20719 2 1864.084535 933.0473 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3827.8 - 513020 - - - 2.3781 - 3.525 0.638 - 823.5 1 2 0 0.0044 18 0 0 0 1.55E+07 1.05E+07 - - - 6.8493 0.999 230117_WJC_METTL3_WT_vs_EV_F04.20724.20724.2 0.00478 16-Sep K.IGFPWSEIR[166.11].N "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 1113.5847 0.58 34745 20724 2 1113.587785 557.7996 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 6 3828.5 - 1.21E+07 - - - 2.8152 - 1.523 0.373 - 200.7 1 2 0 0.0031 9 0 0 0 1.93E+07 3.30E+07 - - - 3.012 0.9923 230117_WJC_METTL3_WT_vs_EV_F04.20726.20726.2 0.0433 14-Aug R.VIFGLFGK[136.11].T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 887.536 0.62 34747 20726 2 887.534679 444.7753 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.72 3828.6 - 2.22E+07 - - - -1.5166 - 1.434 0.213 - 211.9 1 2 0 -0.0013 8 0 0 0 2.76E+07 4.45E+07 - - - 1.7009 1 230117_WJC_METTL3_WT_vs_EV_F04.20727.20727.3 2.92E-07 16/52 K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.28 34748 20727 3 1416.841093 473.2883 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3828.6 - 7.96E+06 - - - -1.4631 - 3.155 0.557 - 347.2 1 2 0 -0.0021 14 0 0 0 3.00E+07 2.35E+07 - - - 7.8029 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.20734.20734.2 0.00528 16-Sep K.IIAATFLFK.W sp|Q13907|IDI1_HUMAN 1 1022.6165 5.15 34755 20734 2 1022.616627 512.3155 Isopentenyl-diphosphate Delta-isomerase 1 OS=Homo sapiens OX=9606 GN=IDI1 PE=1 SV=2 8.75 3829.5 - 1.91E+06 - - - 0.1692 - 1.742 0.258 - 175.7 1 2 0 0.0002 9 0 0 0 4.29E+06 8.33E+05 - - - 2.5523 0.9956 230117_WJC_METTL3_WT_vs_EV_F04.20738.20738.2 0.177 14-Aug K.LLELLWNK.Y "sp|Q92905|CSN5_HUMAN,tr|E5RHH5|E5RHH5_HUMAN" 2 1027.6066 1.09 34759 20738 2 1027.605212 514.8106 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 6 3830 - 1.21E+06 - - - -1.3673 - 1.784 0.182 - 183.8 1 2 0 -0.0014 8 0 0 0 2.89E+06 2.66E+06 - - - 2.1306 1 230117_WJC_METTL3_WT_vs_EV_F04.20740.20740.2 0.000141 24-Oct R.ILFIGGITAPTVR.Q sp|P48651|PTSS1_HUMAN 1 1356.8129 -1 34761 20740 2 1356.811539 679.4137 Phosphatidylserine synthase 1 OS=Homo sapiens OX=9606 GN=PTDSS1 PE=1 SV=1 9.75 3830.3 - 983391 - - - -1.0193 - 2.405 0.449 - 278.8 1 2 0 -0.0014 13 0 0 0 0.00E+00 0.00E+00 - - - 4.6091 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.20741.20741.2 0.016 26-Jul R.LFLVGSSLNGFGTR.S "sp|Q6PIY7|GLD2_HUMAN,tr|D6RAF2|D6RAF2_HUMAN" 2 1466.7882 -1 34762 20741 2 1466.789784 734.4014 Poly(A) RNA polymerase GLD2 OS=Homo sapiens OX=9606 GN=TENT2 PE=1 SV=1 9.75 3830.4 - 982105 - - - 1.1045 - 1.632 0.327 - 97.5 1 2 0 0.0016 14 0 0 0 0.00E+00 0.00E+00 - - - 2.6849 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20742.20742.2 1.64E-05 26-Sep K.VLFLLGADGGC[160.03]ITR[166.11].Q "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1500.7998 1.8 34763 20742 2 1500.800314 751.4072 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 5.8 3830.5 - 962145 - - - 0.3392 - 2.238 0.434 - 240 1 2 0 0.0005 14 0 0 0 4.90E+06 2.72E+06 - - - 4.2679 0.976 230117_WJC_METTL3_WT_vs_EV_F04.20743.20743.2 0.0848 26-Oct R.LFLVGSSLNGFGTR[166.11].S "sp|Q6PIY7|GLD2_HUMAN,tr|D6RAF2|D6RAF2_HUMAN" 2 1476.7964 -1 34764 20743 2 1476.791242 739.4055 Poly(A) RNA polymerase GLD2 OS=Homo sapiens OX=9606 GN=TENT2 PE=1 SV=1 9.75 3830.7 - 824411 - - - -3.5157 - 1.414 0.255 - 118.5 1 2 0 -0.0052 14 0 0 0 0.00E+00 0.00E+00 - - - 1.7921 1 230117_WJC_METTL3_WT_vs_EV_F04.20745.20745.2 0.00111 13/26 K.VLFLLGADGGC[160.03]ITR.Q "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1490.7915 1.8 34765 20745 2 1490.791397 746.403 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 5.8 3831 - 125746 - - - -0.0926 - 2.415 0.487 - 477.3 1 2 0 -0.0001 14 0 0 0 4.90E+06 2.72E+06 - - - 4.8505 0.9514 230117_WJC_METTL3_WT_vs_EV_F04.20746.20746.2 0.242 12-Jun R.LGFDLFK.E "sp|Q9UIV8|SPB13_HUMAN,tr|F8WE70|F8WE70_HUMAN,tr|C9JL93|C9JL93_HUMAN,tr|A0A0A0MQW3|A0A0A0MQW3_HUMAN" 4 838.4589 -1 34766 20746 2 838.455931 420.2367 Serpin B13 OS=Homo sapiens OX=9606 GN=SERPINB13 PE=1 SV=2 5.84 3831.1 - 194290 - - - -3.5291 - 1.219 0.206 - 69.2 1 2 0 -0.003 7 0 0 0 0.00E+00 0.00E+00 - - - 1.1891 1 230117_WJC_METTL3_WT_vs_EV_F04.20747.20747.2 2.93E-07 24-Dec K.MVFINNIALAQIK.N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1473.8378 1.1 34767 20747 2 1473.84063 737.9262 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3831.2 - 389458 - - - 1.95 - 2.671 0.593 - 438.1 1 2 0 0.0029 13 0 0 0 1.96E+07 1.79E+07 - - - 5.9415 1 230117_WJC_METTL3_WT_vs_EV_F04.20748.20748.2 3.03E-05 13/24 K.MVFINNIALAQIK[136.11].N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1481.852 1.1 34768 20748 2 1481.854383 741.9333 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3831.3 - 385986 - - - 1.6378 - 2.689 0.557 - 522.1 1 2 0 0.0024 13 0 0 0 1.96E+07 1.79E+07 - - - 5.693 1 230117_WJC_METTL3_WT_vs_EV_F04.20751.20751.2 9.76E-09 13/32 R.FLVGPYQNTIGAAFVAK.V "sp|Q969Q5|RAB24_HUMAN,tr|D6RFW3|D6RFW3_HUMAN" 2 1794.9669 -1 34771 20751 2 1794.961257 898.4907 Ras-related protein Rab-24 OS=Homo sapiens OX=9606 GN=RAB24 PE=1 SV=1 8.59 3831.6 - 126482 - - - -3.1193 - 2.586 0.627 - 302 1 2 0 -0.0056 17 0 0 0 0.00E+00 0.00E+00 - - - 6.0062 0.99 230117_WJC_METTL3_WT_vs_EV_F04.20755.20755.2 0.00406 20-Sep K.ELGIWEPLAVK.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1253.702 9.21 34773 20755 2 1253.697408 627.8583 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3832.2 - 3.75E+06 - - - -3.642 - 1.767 0.299 - 283.5 1 2 0 -0.0046 11 0 0 0 6.65E+08 7.22E+07 - - - 2.788 1 230117_WJC_METTL3_WT_vs_EV_F04.20756.20756.2 9.00E-05 24-Oct K.VLGTAFDPFLGGK.N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1320.7078 9.08 34774 20756 2 1320.703297 661.3612 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3832.3 - 2.37E+06 - - - -3.4004 - 2.065 0.537 - 210 1 2 0 -0.0045 13 0 0 0 2.73E+08 3.00E+07 - - - 4.8669 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.20758.20758.2 0.00741 14-Jul K.EALLELLR.L sp|Q13895|BYST_HUMAN 1 955.5702 1.09 34776 20758 2 955.570484 478.7924 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3832.4 - 1.27E+06 - - - 0.2637 - 1.835 0.331 - 182.4 1 2 0 0.0003 8 0 0 0 2.89E+07 2.66E+07 - - - 3.3165 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20759.20759.2 0.0168 14-Sep K.EALLELLR[166.11].L sp|Q13895|BYST_HUMAN 1 965.5785 1.09 34777 20759 2 965.579243 483.7965 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3832.6 - 1.15E+06 - - - 0.7674 - 2.033 0.312 - 325.7 1 2 0 0.0007 8 0 0 0 2.89E+07 2.66E+07 - - - 3.4851 1 230117_WJC_METTL3_WT_vs_EV_F04.20761.20761.2 0.000114 18-Sep R.QALTDFLLAR[166.11].K "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1156.648 1.28 34779 20761 2 1156.649901 579.3313 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.84 3832.8 - 737217 - - - 1.6626 - 2.201 0.461 - 278 1 2 0 0.0019 10 0 0 0 4.55E+06 3.54E+06 - - - 4.6474 0.9117 230117_WJC_METTL3_WT_vs_EV_F04.20763.20763.2 0.52 12-May K.LNIWDWK.T sp|O60508|PRP17_HUMAN 1 973.5022 0.76 34781 20763 2 973.498489 487.7584 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.84 3833.1 - 627512 - - - -3.7627 - 1.353 0.129 - 74.2 2 2 0 -0.0037 7 0 0 0 1.63E+06 2.14E+06 - - - 0.8161 0.9887 230117_WJC_METTL3_WT_vs_EV_F04.20764.20764.2 0.539 12-Aug K.LLDFLIK.S "sp|Q13255|GRM1_HUMAN,sp|Q92621|NU205_HUMAN" 2 860.5371 1.84 34782 20764 2 860.537149 431.2758 Metabotropic glutamate receptor 1 OS=Homo sapiens OX=9606 GN=GRM1 PE=1 SV=3 5.84 3833.2 - 415296 - - - 0.0093 - 1.463 0.055 - 147 1 2 0 0 7 0 0 0 1.48E+06 8.05E+05 - - - 0.6528 1 230117_WJC_METTL3_WT_vs_EV_F04.20765.20765.2 8.74E-10 14/30 R.LIADLGSTSITNLGFR[166.11].D sp|Q92520|FAM3C_HUMAN 1 1686.918 -1 34783 20765 2 1686.919828 844.4663 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 5.84 3833.3 - 360727 - - - 1.0807 - 2.994 0.644 - 566.3 1 2 0 0.0018 16 0 0 0 0.00E+00 0.00E+00 - - - 6.4931 0.8866 230117_WJC_METTL3_WT_vs_EV_F04.20767.20767.2 0.0935 22-Aug K.SLSPFAITYLDR.L "sp|Q6NUQ4|TM214_HUMAN,tr|H7C0H8|H7C0H8_HUMAN,tr|H7C085|H7C085_HUMAN" 3 1381.7242 -1 34785 20767 2 1381.72038 691.8694 Transmembrane protein 214 OS=Homo sapiens OX=9606 GN=TMEM214 PE=1 SV=2 5.55 3833.6 - 195922 - - - -2.7401 - 1.435 0.044 - 142.6 2 2 0 -0.0038 12 0 0 0 0.00E+00 0.00E+00 - - - 0.1806 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.20775.20775.2 0.00166 20-Nov K.ELGIWEPLAVK[136.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1261.7162 9.21 34792 20775 2 1261.712811 631.8654 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3834.4 - 5.02E+06 - - - -2.6654 - 1.963 0.308 - 429.2 1 2 0 -0.0034 11 0 0 0 6.65E+08 7.22E+07 - - - 3.1394 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.20776.20776.2 0.00215 13/22 R.LALFNPDVC[160.03]WDR.N sp|O00483|NDUA4_HUMAN 1 1504.7133 2.19 34793 20776 2 1504.710746 753.3639 Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1 4.21 3834.6 - 1.88E+06 - - - -1.6867 - 2.522 0.412 - 679.4 1 2 0 -0.0025 12 0 0 0 7.31E+06 3.33E+06 - - - 4.5172 1 230117_WJC_METTL3_WT_vs_EV_F04.20778.20778.2 3.37E-06 15/24 K.LLEQALVIEEQLR.R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1552.8825 1.6 34795 20778 2 1552.879864 777.4485 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3834.8 - 1.40E+06 - - - -1.6704 - 3.077 0.397 - 917.4 1 2 0 -0.0026 13 0 0 0 1.35E+07 8.45E+06 - - - 4.8571 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.20779.20779.2 0.169 20-Nov K.TLPLFYGSIVR[166.11].F "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1274.7262 1.23 34796 20779 2 1274.724635 638.3704 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 8.41 3834.9 - 1.37E+06 - - - -1.2505 - 1.918 0.272 - 440.7 1 2 0 -0.0016 11 0 0 0 1.93E+07 1.57E+07 - - - 2.8114 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20780.20780.2 0.0028 20-Sep K.SLPASLSFLVK.L "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN" 5 1160.6805 1.35 34797 20780 2 1160.682715 581.3475 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 8.47 3835.1 - 1.31E+06 - - - 1.8989 - 1.66 0.339 - 169 1 2 0 0.0022 11 0 0 0 5.14E+06 3.81E+06 - - - 2.9152 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.20782.20782.2 0.000477 18-Oct R.QALTDFLLAR.K "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1146.6397 1.1 34799 20782 2 1146.637477 574.3271 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.84 3835.3 - 1.25E+06 - - - -1.9457 - 2.144 0.346 - 250.4 1 2 0 -0.0022 10 0 0 0 3.89E+06 3.54E+06 - - - 3.7247 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20784.20784.2 0.00102 24-Dec K.ALVLANPEVSLWR.K "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 1466.8245 -1 34801 20784 2 1466.824542 734.4196 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6.05 3835.6 - 1.13E+06 - - - -0.0048 - 2.543 0.405 - 489.4 1 2 0 0 13 0 0 0 0.00E+00 0.00E+00 - - - 4.4278 1 230117_WJC_METTL3_WT_vs_EV_F04.20785.20785.2 4.52E-05 30-Dec R.IASLPVEVQEVSLLDK.L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1738.9717 3.42 34802 20785 2 1738.967975 870.4931 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.14 3835.7 - 1.13E+06 - - - -2.1231 - 2.252 0.483 - 304.1 1 2 0 -0.0037 16 0 0 0 1.90E+07 5.54E+06 - - - 4.6032 1 230117_WJC_METTL3_WT_vs_EV_F04.20786.20786.2 2.12E-05 14/26 K.LGLVGVNLTLDGVK.S "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 1396.829 1.34 34803 20786 2 1396.827394 699.4218 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 3835.9 - 1.08E+06 - - - -1.1254 - 2.701 0.532 - 588.5 1 2 0 -0.0016 14 0 0 0 2.60E+07 1.94E+07 - - - 5.4633 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.20787.20787.2 0.000294 16/24 K.LLEQALVIEEQLR[166.11].R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1562.8907 -1 34804 20787 2 1562.888732 782.4526 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3836 - 1.07E+06 - - - -1.2771 - 2.809 0.371 - 1220.7 1 2 0 -0.002 13 0 0 0 0.00E+00 0.00E+00 - - - 4.4314 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.20788.20788.2 0.0252 18-Oct K.EFLFNPYLTR[166.11].K "sp|P13378|HXD8_HUMAN,sp|P31273|HXC8_HUMAN,sp|P17481|HXB8_HUMAN,tr|I3L3R1|I3L3R1_HUMAN,tr|I3L383|I3L383_HUMAN,tr|A0A0A0MSX5|A0A0A0MSX5_HUMAN,tr|A0A0A0MTF4|A0A0A0MTF4_HUMAN" 7 1308.6742 1.15 34805 20788 2 1308.6756 655.3444 Homeobox protein Hox-D8 OS=Homo sapiens OX=9606 GN=HOXD8 PE=1 SV=2 6.1 3836.1 - 1.03E+06 - - - 1.0751 - 1.629 0.292 - 209.1 1 2 0 0.0014 10 0 0 0 7.85E+06 6.83E+06 - - - 2.5593 0.998 230117_WJC_METTL3_WT_vs_EV_F04.20789.20789.2 0.000833 22-Dec R.LALFNPDVC[160.03]WDR[166.11].N sp|O00483|NDUA4_HUMAN 1 1514.7216 2.06 34806 20789 2 1514.719052 758.3681 Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1 4.21 3836.3 - 925226 - - - -1.6518 - 1.816 0.36 - 498.8 1 2 0 -0.0025 12 0 0 0 7.31E+06 3.54E+06 - - - 3.269 0.976 230117_WJC_METTL3_WT_vs_EV_F04.20790.20790.2 0.117 30-Oct R.LIADLGSTSITNLGFR.D sp|Q92520|FAM3C_HUMAN 1 1676.9097 -1 34807 20790 2 1676.905108 839.4621 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 5.84 3836.4 - 792158 - - - -2.7592 - 1.323 0.225 - 105.5 1 2 0 -0.0046 16 0 0 0 0.00E+00 0.00E+00 - - - 1.3895 1 230117_WJC_METTL3_WT_vs_EV_F04.20791.20791.2 2.42E-07 26-Dec K.NLPIYSEEIVEMYK.G "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1726.8488 1.45 34808 20791 2 1726.843055 864.4317 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3836.5 - 734902 - - - -3.3124 - 2.666 0.554 - 361.6 1 2 0 -0.0057 14 0 0 0 5.93E+06 4.08E+06 - - - 5.5918 0.993 230117_WJC_METTL3_WT_vs_EV_F04.20793.20793.2 0.0272 20-Sep R.LLLQAIQSFEK.K "sp|O14920|IKKB_HUMAN,tr|A0A499FJS7|A0A499FJS7_HUMAN" 2 1288.7391 1.44 34809 20793 2 1288.734893 645.3768 Inhibitor of nuclear factor kappa-B kinase subunit beta OS=Homo sapiens OX=9606 GN=IKBKB PE=1 SV=1 6 3836.9 - 910860 - - - -3.2551 - 1.759 0.337 - 98.7 2 2 0 -0.0042 11 0 0 0 7.70E+06 5.34E+06 - - - 2.9221 1 230117_WJC_METTL3_WT_vs_EV_F04.20794.20794.2 0.000216 20-Dec R.QLLEEMLTSYR.L sp|O75688|PPM1B_HUMAN 1 1381.6912 0.46 34810 20794 2 1381.684406 691.8529 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3837 - 3.89E+06 - - - -4.8824 - 2.549 0.532 - 708.1 1 2 0 -0.0067 11 0 0 0 3.77E+07 8.20E+07 - - - 5.4995 1 230117_WJC_METTL3_WT_vs_EV_F04.20795.20795.2 7.46E-08 14/24 K.VLGTAFDPFLGGK[136.11].N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1328.722 9.1 34811 20795 2 1328.718928 665.3683 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3837.1 - 7.02E+06 - - - -2.303 - 2.613 0.608 - 450.3 1 2 0 -0.0031 13 0 0 0 2.73E+08 3.00E+07 - - - 5.9959 1 230117_WJC_METTL3_WT_vs_EV_F04.20796.20796.2 1.32E-05 16/26 K.LGLVGVNLTLDGVK[136.11].S "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 1404.8432 -1 34812 20796 2 1404.840762 703.4289 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 3837.2 - 4.47E+06 - - - -1.7112 - 3.32 0.529 - 927.2 1 2 0 -0.0024 14 0 0 0 0.00E+00 0.00E+00 - - - 5.9587 1 230117_WJC_METTL3_WT_vs_EV_F04.20799.20799.2 1.05E-08 17/28 K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 -1 34815 20799 2 1521.87165 761.945 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3837.5 - 2.55E+06 - - - -2.472 - 3.151 0.641 - 875.7 1 2 0 -0.0038 15 0 0 0 0.00E+00 0.00E+00 - - - 6.596 1 230117_WJC_METTL3_WT_vs_EV_F04.20800.20800.2 3.51E-07 15/28 K.TVAGQDAVIVLLGTR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1511.8671 -1 34816 20800 2 1511.863889 756.9408 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3837.6 - 2.18E+06 - - - -2.1516 - 3.059 0.615 - 612.6 1 2 0 -0.0033 15 0 0 0 0.00E+00 0.00E+00 - - - 6.3312 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20801.20801.2 6.66E-05 20-Nov K.LLPAITILGC[160.03]R.V "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 2 1225.7217 2.48 34817 20801 2 1225.721906 613.8681 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 8.25 3837.8 - 1.97E+06 - - - 0.1974 - 2.114 0.37 - 422.7 1 2 0 0.0002 11 0 0 0 1.54E+07 6.21E+06 - - - 3.7988 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.20802.20802.3 0.00023 13/48 K.LLEQALVIEEQLR.R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1552.8825 1.56 34818 20802 3 1552.881231 518.6348 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3837.9 - 1.53E+06 - - - -0.7901 - 2.587 0.461 - 277.1 1 2 0 -0.0012 13 0 0 0 6.85E+06 4.40E+06 - - - 6.2564 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.20804.20804.3 5.01E-07 15/56 K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 0.99 34820 20804 3 1521.874233 508.2991 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3838.1 - 1.34E+06 - - - -0.7747 - 2.604 0.459 - 389.7 1 2 0 -0.0012 15 0 0 0 6.10E+06 6.16E+06 - - - 6.1544 1 230117_WJC_METTL3_WT_vs_EV_F04.20805.20805.3 5.53E-07 17/56 K.TVAGQDAVIVLLGTR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1511.8671 0.94 34821 20805 3 1511.865012 504.963 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3838.2 - 1.19E+06 - - - -1.4089 - 2.932 0.576 - 476.8 1 2 0 -0.0021 15 0 0 0 6.10E+06 6.49E+06 - - - 7.7681 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.20806.20806.2 0.0216 18-Sep K.EFLFNPYLTR.K "sp|P13378|HXD8_HUMAN,sp|P31273|HXC8_HUMAN,sp|P17481|HXB8_HUMAN,tr|I3L3R1|I3L3R1_HUMAN,tr|I3L383|I3L383_HUMAN,tr|A0A0A0MSX5|A0A0A0MSX5_HUMAN,tr|A0A0A0MTF4|A0A0A0MTF4_HUMAN" 7 1298.6659 1.04 34822 20806 2 1298.66417 650.3402 Homeobox protein Hox-D8 OS=Homo sapiens OX=9606 GN=HOXD8 PE=1 SV=2 6.1 3838.4 - 1.10E+06 - - - -1.3498 - 2.029 0.387 - 336.3 1 2 0 -0.0018 10 0 0 0 7.11E+06 6.83E+06 - - - 3.8738 0.9928 230117_WJC_METTL3_WT_vs_EV_F04.20808.20808.3 0.0069 13/48 K.LLEQALVIEEQLR[166.11].R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1562.8907 1.56 34824 20808 3 1562.888598 521.9709 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3838.6 - 1.04E+06 - - - -1.3629 - 2.021 0.188 - 262.8 1 2 0 -0.0021 13 0 0 0 6.85E+06 4.40E+06 - - - 2.5431 1 230117_WJC_METTL3_WT_vs_EV_F04.20809.20809.2 0.00151 22-Dec K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 1.29 34825 20809 2 1314.789091 658.4028 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3838.8 - 800277 - - - -1.5463 - 2.239 0.466 - 492.5 1 2 0 -0.002 12 0 0 0 1.28E+08 9.95E+07 - - - 4.603 0.93 230117_WJC_METTL3_WT_vs_EV_F04.20810.20810.2 1.15E-05 20-Oct D.GMVPFVFVGTK[136.11].E "sp|P51114|FXR1_HUMAN,sp|Q06787|FMR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 9 1188.6457 0.82 34826 20810 2 1188.64427 595.3301 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 8.75 3838.9 - 601720 - - - -1.1627 - 1.89 0.44 - 243.9 1 1 0 -0.0014 11 0 0 0 5.45E+06 6.61E+06 - - - 4.0125 1 230117_WJC_METTL3_WT_vs_EV_F04.20812.20812.2 1.62E-05 13/28 R.LISEILSESVVPDVR.S "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 11 1654.9142 -1 34828 20812 2 1654.910068 828.4644 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.14 3839.1 - 545911 - - - -2.4678 - 2.873 0.551 - 458.1 1 2 0 -0.0041 15 0 0 0 0.00E+00 0.00E+00 - - - 5.704 1 230117_WJC_METTL3_WT_vs_EV_F04.20815.20815.2 2.03E-07 14/30 R.LPC[160.03]IYLVDSGGAYLPR.Q "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJW5|A0A804HJW5_HUMAN,tr|A0A0G2JM88|A0A0G2JM88_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HIH3|A0A804HIH3_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|D6RDF7|D6RDF7_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HJW2|A0A804HJW2_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|D6R9R1|D6R9R1_HUMAN,tr|A0A804HHS4|A0A804HHS4_HUMAN,tr|A0A0S2Z5R4|A0A0S2Z5R4_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 16 1792.9182 -1 34830 20815 2 1792.914561 897.4664 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.83 3839.5 - 922231 - - - -2.0252 - 3.004 0.594 - 674.5 1 2 0 -0.0036 16 0 0 0 0.00E+00 0.00E+00 - - - 6.1314 1 230117_WJC_METTL3_WT_vs_EV_F04.20821.20821.2 6.88E-09 13/24 R.LGSTIFVANLDFK.V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1423.7711 1.95 34836 20821 2 1423.766826 712.8928 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3840.3 - 1.19E+06 - - - -3.0138 - 2.862 0.565 - 713.2 1 2 0 -0.0043 13 0 0 0 2.84E+07 1.46E+07 - - - 5.9115 0.9357 230117_WJC_METTL3_WT_vs_EV_F04.20823.20823.2 0.00304 16-Jul R.FYTLIPHDF.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1151.5651 - 34838 20823 2 1151.565079 576.7898 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.08 3840.5 - 929402 - - - -0.0591 - 1.316 0.435 - 121.2 1 1 0 -0.0001 9 0 0 0 - - - - - 3.0483 0.9945 230117_WJC_METTL3_WT_vs_EV_F04.20824.20824.2 1.67E-06 28-Aug R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 -1 34839 20824 2 2001.965164 1001.9941 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3840.7 - 833160 - - - -4.2803 - 1.895 0.533 - 92.4 1 2 0 -0.0086 15 0 0 0 0.00E+00 0.00E+00 - - - 4.5466 0.9984 230117_WJC_METTL3_WT_vs_EV_F04.20826.20826.2 0.00277 14-Oct R.QVLPFLLR.R "sp|O14981|BTAF1_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 2 984.612 1.41 34841 20826 2 984.610051 493.3133 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 9.75 3840.9 - 793567 - - - -2.017 - 1.847 0.421 - 410 1 2 0 -0.002 8 0 0 0 2.77E+06 1.97E+06 - - - 4.0004 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20837.20837.2 0.000273 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 7199.95 34851 20837 2 1603.764678 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3842.2 - 3.67E+07 - - - 0.4602 - 1.888 0.498 - 197.9 1 2 0 0.0007 12 0 0 0 1.95E+09 2.71E+05 - - - 4.3912 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.20841.20841.2 0.042 20-Aug K.VPPPWLIAMQR.Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1306.722 1.63 34855 20841 2 1306.722805 654.3683 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3842.5 - 691627 - - - 0.6176 - 1.412 0.274 - 198.7 1 2 0 0.0008 11 0 0 0 1.77E+07 1.09E+07 - - - 1.9978 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.20842.20842.2 3.30E-05 18-Aug K.GYGFVSFFNK.W "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN" 4 1164.5604 0.53 34856 20842 2 1164.558473 583.2875 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 8.59 3842.6 - 515305 - - - -1.6504 - 1.668 0.517 - 193.7 1 2 0 -0.0019 10 0 0 0 3.64E+06 6.90E+06 - - - 4.2871 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20847.20847.2 3.01E-05 16-Sep R.MLYVWALC[160.03]R.D "sp|O43615|TIM44_HUMAN,tr|M0QXM9|M0QXM9_HUMAN" 2 1210.5991 3.05 34861 20847 2 1210.599884 606.3068 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 7.98 3843.2 - 285868 - - - 0.6427 - 1.891 0.402 - 384.8 1 2 0 0.0008 9 0 0 0 8.45E+06 2.77E+06 - - - 3.8531 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20849.20849.3 0.00509 Aug-40 K.VPPPWLIAMQR.Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1306.722 1.37 34863 20849 3 1306.721817 436.5813 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3843.5 - 159484 - - - -0.1385 - 1.684 0.345 - 126 1 2 0 -0.0002 11 0 0 0 1.49E+06 1.09E+06 - - - 3.8669 1 230117_WJC_METTL3_WT_vs_EV_F04.20855.20855.2 7.12E-05 13/22 K.LVTLPVSFAQLK[136.11].N sp|Q96AG4|LRC59_HUMAN 1 1322.8053 1.29 34866 20855 2 1322.805984 662.4099 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3844.2 - 2.74E+07 - - - 0.4989 - 2.28 0.504 - 569.3 1 2 0 0.0007 12 0 0 0 1.28E+08 9.95E+07 - - - 4.9319 1 230117_WJC_METTL3_WT_vs_EV_F04.20857.20857.2 6.90E-07 15/26 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.89 34868 20857 2 1669.890838 835.9552 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3844.4 - 3.91E+06 - - - -3.0493 - 2.592 0.582 - 753.3 1 2 0 -0.0051 14 0 0 0 8.97E+07 1.01E+08 - - - 5.7281 1 230117_WJC_METTL3_WT_vs_EV_F04.20858.20858.2 3.39E-09 14/26 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.89 34869 20858 2 1661.877241 831.9481 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3844.5 - 2.84E+06 - - - -2.7012 - 2.561 0.635 - 576.9 1 2 0 -0.0045 14 0 0 0 8.97E+07 1.01E+08 - - - 6.0896 0.9504 230117_WJC_METTL3_WT_vs_EV_F04.20860.20860.2 0.000121 20-Oct R.DINAVLIDMER.Q "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1287.6493 1.33 34871 20860 2 1287.637004 644.8319 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.03 3844.8 - 2.09E+06 - - - -9.5391 - 2.219 0.456 - 430.1 1 2 0 -0.0123 11 0 0 0 7.69E+06 5.76E+06 - - - 4.5614 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.20864.20864.3 0.000195 Dec-48 K.GFVHPDPLWIPFK.E "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 1551.8238 1.46 34875 20864 3 1551.824139 518.2819 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 6.74 3845.3 - 1.23E+06 - - - 0.2049 - 2.067 0.371 - 172.9 1 2 0 0.0003 13 0 0 0 2.95E+06 2.02E+06 - - - 4.6449 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20867.20867.3 0.00185 Sep-44 R.EGFLDTLVVLHR.A "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 1397.7667 1.67 34878 20867 3 1397.766949 466.9295 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.32 3845.7 - 989861 - - - 0.1781 - 2.048 0.309 - 95.5 1 2 0 0.0002 12 0 0 0 2.88E+06 1.72E+06 - - - 3.972 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20872.20872.3 0.00234 Oct-44 K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 1.38 34883 20872 3 1314.790744 439.271 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3846.4 - 599435 - - - -0.289 - 1.826 0.364 - 161.5 1 2 0 -0.0004 12 0 0 0 2.01E+06 1.46E+06 - - - 4.2671 1 230117_WJC_METTL3_WT_vs_EV_F04.20877.20877.2 1.36E-05 20-Oct R.WPDPEDLLTPR.W sp|Q8TAE8|G45IP_HUMAN 1 1337.6616 -1 34887 20877 2 1337.661193 669.8381 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.03 3847 - 415579 - - - -0.2788 - 2.108 0.528 - 360.7 1 2 0 -0.0004 11 0 0 0 0.00E+00 0.00E+00 - - - 4.9581 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20878.20878.2 0.161 16-Sep K.ITFLLQAIR.N "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1073.6597 1.3 34888 20878 2 1073.659857 537.8371 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 3847.1 - 5.24E+06 - - - 0.1313 - 2.049 0.38 - 254 1 2 0 0.0001 9 0 0 0 1.77E+07 1.36E+07 - - - 3.923 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20879.20879.2 0.000493 16-Sep K.TLDDLFPLR.S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1088.5866 1.35 34889 20879 2 1088.586492 545.3006 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.21 3847.1 - 4.94E+06 - - - -0.1084 - 1.89 0.46 - 273.7 1 2 0 -0.0001 9 0 0 0 1.93E+07 1.43E+07 - - - 4.2802 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20880.20880.2 0.0141 16-Oct K.ITFLLQAIR[166.11].N "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1083.668 1.29 34890 20880 2 1083.668294 542.8413 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 3847.2 - 3.65E+06 - - - 0.2842 - 1.717 0.345 - 288.9 1 2 0 0.0003 9 0 0 0 1.76E+07 1.36E+07 - - - 3.153 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20881.20881.2 0.00413 20-Dec K.VSVFFGGLSIK.K "sp|O00148|DX39A_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|A0A0D9SEM9|A0A0D9SEM9_HUMAN" 3 1152.6543 0.53 34891 20881 2 1152.65517 577.3344 ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2 8.72 3847.2 - 3.54E+06 - - - 0.7582 - 1.963 0.453 - 431.5 1 2 0 0.0009 11 0 0 0 1.42E+07 2.68E+07 - - - 4.2112 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.20882.20882.3 7.12E-05 Oct-52 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.9 34892 20882 3 1661.882908 554.9679 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3847.3 - 3.13E+06 - - - 0.7088 - 2.229 0.473 - 97.8 1 2 0 0.0012 14 0 0 0 1.16E+07 1.29E+07 - - - 5.9433 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20883.20883.2 0.000215 20-Nov K.VAVFFGGLSIK[136.11].K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1144.6736 0.84 34893 20883 2 1144.673814 573.3441 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3847.4 - 2.90E+06 - - - 0.2036 - 2.174 0.451 - 358.4 1 2 0 0.0002 11 0 0 0 1.71E+07 2.04E+07 - - - 4.4728 1 230117_WJC_METTL3_WT_vs_EV_F04.20884.20884.2 0.00116 20-Dec K.VAVFFGGLSIK.K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1136.6594 0.83 34894 20884 2 1136.659876 569.337 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3847.5 - 2.44E+06 - - - 0.4355 - 2.513 0.543 - 568.3 1 2 0 0.0005 11 0 0 0 1.69E+07 2.03E+07 - - - 5.5443 1 230117_WJC_METTL3_WT_vs_EV_F04.20886.20886.2 6.17E-05 13/22 K.TLQTISLLGYMK.H sp|O60264|SMCA5_HUMAN 1 1366.753 1.02 34896 20886 2 1366.75322 684.3838 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 8.26 3847.7 - 1.52E+06 - - - 0.1434 - 2.31 0.539 - 481.4 1 2 0 0.0002 12 0 0 0 4.23E+06 4.13E+06 - - - 5.2249 1 230117_WJC_METTL3_WT_vs_EV_F04.20887.20887.2 0.0166 18-Dec R.MALLATVLGR.F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1043.6161 2.19 34897 20887 2 1043.616583 522.8153 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.5 3847.8 - 1.26E+06 - - - 0.4283 - 2.376 0.45 - 658.9 1 2 0 0.0004 10 0 0 0 2.32E+07 1.06E+07 - - - 4.7802 1 230117_WJC_METTL3_WT_vs_EV_F04.20890.20890.2 3.45E-06 24-Dec R.VLLFTDDVALVSK.A "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1418.8021 1.56 34900 20890 2 1418.803939 710.4083 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.21 3848.2 - 1.03E+06 - - - 1.3089 - 2.607 0.587 - 415.5 1 2 0 0.0019 13 0 0 0 6.27E+06 4.02E+06 - - - 5.8352 1 230117_WJC_METTL3_WT_vs_EV_F04.20891.20891.2 1.07E-06 20-Oct K.VLYVYDMLAGK.L "sp|Q9Y5J1|UTP18_HUMAN,tr|J3KSR7|J3KSR7_HUMAN" 2 1270.6631 0.99 34901 20891 2 1270.665255 636.3388 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 5.8 3848.3 - 1.01E+06 - - - 1.6598 - 2.137 0.57 - 327.1 1 2 0 0.0021 11 0 0 0 5.23E+06 5.30E+06 - - - 5.3047 1 230117_WJC_METTL3_WT_vs_EV_F04.20892.20892.2 2.07E-05 20-Aug K.VLYVYDMLAGK[136.11].L "sp|Q9Y5J1|UTP18_HUMAN,tr|J3KSR7|J3KSR7_HUMAN" 2 1278.6773 0.99 34902 20892 2 1278.678563 640.3459 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 5.8 3848.4 - 955432 - - - 0.9518 - 2.014 0.537 - 167 1 2 0 0.0012 11 0 0 0 5.23E+06 5.30E+06 - - - 4.9009 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20893.20893.2 0.0168 14-Aug R.DFLLDIAR.Q "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 961.5233 1.5 34903 20893 2 961.524201 481.7689 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 3848.6 - 755684 - - - 0.9558 - 1.713 0.401 - 297 1 2 0 0.0009 8 0 0 0 2.29E+07 1.53E+07 - - - 3.6258 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.20903.20903.3 0.0572 14/52 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.9 34910 20903 3 1669.894465 557.6393 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3849.9 - 2.74E+06 - - - -0.8773 - 1.827 0.311 - 242.5 1 2 0 -0.0015 14 0 0 0 1.16E+07 1.29E+07 - - - 3.6086 0.9885 230117_WJC_METTL3_WT_vs_EV_F04.20904.20904.2 0.35 22-Sep K.DAGQISGLNVLR[166.11].V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1251.6811 4.73 34911 20904 2 1251.678924 626.8478 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 3850 - 6.92E+06 - - - -1.7145 - 1.46 0.193 - 162.3 1 2 0 -0.0021 12 0 0 0 3.39E+08 7.18E+07 - - - 1.4616 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.20906.20906.2 0.0131 14-Jul R.DFLLDIAR[166.11].Q "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 971.5316 1.48 34913 20906 2 971.53035 486.7731 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 3850.2 - 2.12E+06 - - - -1.2372 - 1.356 0.34 - 191.8 1 2 0 -0.0012 8 0 0 0 2.30E+07 1.56E+07 - - - 2.4703 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20907.20907.2 0.337 18-Dec R.MALLATVLGR[166.11].F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1053.6244 2.19 34914 20907 2 1053.624021 527.8195 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.5 3850.4 - 1.74E+06 - - - -0.3654 - 2.477 0.404 - 698 1 2 0 -0.0004 10 0 0 0 2.32E+07 1.06E+07 - - - 4.5567 1 230117_WJC_METTL3_WT_vs_EV_F04.20909.20909.2 2.56E-06 24-Dec K.SELVAMLEEEELR.K "sp|P40616|ARL1_HUMAN,tr|B4DZG7|B4DZG7_HUMAN,tr|F8VYN9|F8VYN9_HUMAN" 3 1546.7549 1.09 34916 20909 2 1546.746467 774.3847 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 3.98 3850.6 - 1.14E+06 - - - -5.4353 - 2.322 0.514 - 326.2 1 2 0 -0.0084 13 0 0 0 3.94E+06 3.60E+06 - - - 4.9969 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.20914.20914.2 5.27E-09 26-Dec R.WEGPLSVSVFAATK[136.11].E sp|O43505|B4GA1_HUMAN 1 1498.7911 0.84 34921 20914 2 1498.787425 750.4028 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 6 3851.3 - 540676 - - - -2.472 - 2.346 0.347 - 437.5 1 2 0 -0.0037 14 0 0 0 2.08E+06 2.48E+06 - - - 3.7426 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.20919.20919.2 0.000986 12-Jul K.YFLWVVK.F sp|P62993|GRB2_HUMAN 1 953.5375 12.97 34926 20919 2 953.535631 477.776 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 8.59 3851.9 - 277945 - - - -1.9339 - 1.358 0.347 - 164.3 1 2 0 -0.0018 7 0 0 0 5.30E+06 4.09E+05 - - - 2.573 0.9926 230117_WJC_METTL3_WT_vs_EV_F04.20922.20922.3 0.000618 Aug-36 K.YRPLFDYFLK.C "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 1360.718 1.51 34929 20922 3 1360.712245 454.5799 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.5 3852.3 - 161291 - - - -4.1993 - 1.59 0.367 - 79.6 1 2 0 -0.0057 10 0 0 0 3.93E+06 2.61E+06 - - - 3.9844 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.20924.20924.2 0.362 18-Oct R.SDLVLLYELK[136.11].Q sp|Q9NPF5|DMAP1_HUMAN 1 1199.6893 1.18 34930 20924 2 1199.689835 600.8519 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.37 3852.6 - 3.31E+06 - - - 0.4535 - 2.093 0.299 - 342.8 1 2 0 0.0005 10 0 0 0 1.94E+07 1.65E+07 - - - 3.3109 1 230117_WJC_METTL3_WT_vs_EV_F04.20926.20926.2 3.79E-05 14/20 R.TSLGNVVLLLK.S "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1155.7227 1.76 34932 20926 2 1155.72275 578.8686 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 8.41 3852.9 - 5.23E+06 - - - 0.0346 - 2.641 0.453 - 540.9 1 2 0 0 11 0 0 0 1.90E+07 1.08E+07 - - - 5.0141 1 230117_WJC_METTL3_WT_vs_EV_F04.20927.20927.2 0.00012 15/24 K.AAILPTSIFLTNK[136.11].K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1395.8217 0.49 34933 20927 2 1395.821439 698.9181 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3853 - 4.02E+06 - - - -0.1884 - 2.528 0.54 - 592.8 1 2 0 -0.0003 13 0 0 0 5.56E+07 1.13E+08 - - - 5.4096 0.9956 230117_WJC_METTL3_WT_vs_EV_F04.20928.20928.2 1.24 16-Aug R.DLLFQALGR.T sp|Q9NSD9|SYFB_HUMAN 1 1031.5764 3.78 34934 20928 2 1031.577833 516.7955 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 5.84 3853.1 - 3.00E+06 - - - 1.4085 - 1.565 0.1 - 178.8 1 2 0 0.0015 9 0 0 0 3.00E+07 7.92E+06 - - - 1.0749 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20930.20930.2 0.000226 20-Oct R.TSLGNVVLLLK[136.11].S "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1163.7369 1.76 34936 20930 2 1163.737053 582.8757 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 8.41 3853.4 - 2.77E+06 - - - 0.1229 - 2.078 0.364 - 235.8 1 2 0 0.0001 11 0 0 0 1.90E+07 1.08E+07 - - - 3.7081 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20931.20931.2 0.000224 24-Oct K.AAILPTSIFLTNK.K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1387.8075 0.49 34937 20931 2 1387.806971 694.911 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3853.5 - 1.76E+06 - - - -0.3826 - 2.278 0.429 - 249.7 1 2 0 -0.0005 13 0 0 0 5.56E+07 1.13E+08 - - - 4.3224 1 230117_WJC_METTL3_WT_vs_EV_F04.20932.20932.2 2.45E-07 22-Dec K.ITAEEMYDIFGK.Y sp|Q9Y3B4|SF3B6_HUMAN 1 1415.6643 2.18 34938 20932 2 1415.662802 708.8394 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.14 3853.6 - 1.72E+06 - - - -1.0356 - 2.618 0.582 - 585.5 1 2 0 -0.0015 12 0 0 0 5.37E+06 2.47E+06 - - - 5.8715 1 230117_WJC_METTL3_WT_vs_EV_F04.20934.20934.2 0.000915 20-Dec R.FDEISFVNFAR[166.11].G sp|Q08945|SSRP1_HUMAN 1 1353.6593 1.2 34940 20934 2 1353.657428 677.8369 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3853.9 - 1.19E+06 - - - -1.3615 - 2.331 0.454 - 640.7 1 2 0 -0.0018 11 0 0 0 1.53E+07 1.28E+07 - - - 4.6831 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20935.20935.2 0.011 13/24 K.IAVPLIQGYTVLR.L sp|Q8IW92|GLBL2_HUMAN 1 1441.8657 0.95 34941 20935 2 1441.865639 721.9401 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3854 - 1.17E+06 - - - -0.0326 - 2.465 0.409 - 523.4 1 2 0 0 13 0 0 0 1.04E+07 1.10E+07 - - - 4.3774 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20936.20936.2 0.000152 14/24 K.IAVPLIQGYTVLR[166.11].L sp|Q8IW92|GLBL2_HUMAN 1 1451.874 0.95 34942 20936 2 1451.877756 726.9443 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3854.1 - 1.05E+06 - - - 2.6173 - 2.31 0.421 - 639.3 1 2 0 0.0038 13 0 0 0 1.04E+07 1.10E+07 - - - 4.2981 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.20937.20937.2 0.0794 24-Dec R.VLLFTDDVALVSK[136.11].A "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1426.8163 1.56 34943 20937 2 1426.820802 714.4154 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.21 3854.3 - 988504 - - - 3.1679 - 1.905 0.393 - 430.6 1 2 0 0.0045 13 0 0 0 6.27E+06 4.02E+06 - - - 3.5964 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20940.20940.2 0.00066 24-Nov K.LIHIPINNIIVGG.- sp|P60059|SC61G_HUMAN 1 1371.8238 - 34946 20940 2 1371.82421 686.9192 Protein transport protein Sec61 subunit gamma OS=Homo sapiens OX=9606 GN=SEC61G PE=1 SV=1 6.74 3854.7 - 731732 - - - 0.2836 - 2.165 0.356 - 222.9 1 2 0 0.0004 13 0 0 0 - - - - - 3.6527 0.9914 230117_WJC_METTL3_WT_vs_EV_F04.20948.20948.2 0.229 20-Jul K.VPPPWLIAMQR[166.11].Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1316.7303 -1 34953 20948 2 1316.731092 659.3724 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3855.6 - 195506 - - - 0.6258 - 1.37 0.104 - 154.1 1 2 0 0.0008 11 0 0 0 0.00E+00 0.00E+00 - - - 0.6605 1 230117_WJC_METTL3_WT_vs_EV_F04.20958.20958.2 3.58E-08 26-Dec K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 14.69 34961 20958 2 1613.80008 807.9078 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3856.6 - 1.80E+07 - - - -0.6296 - 2.273 0.596 - 349.3 1 2 0 -0.001 14 0 0 0 8.88E+07 6.05E+06 - - - 5.5032 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.20959.20959.2 0.0119 14-Jul R.TLFGFLGK.L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 881.5011 1.27 34962 20959 2 881.501281 441.7578 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3856.7 - 1.06E+07 - - - 0.2167 - 1.252 0.363 - 143.8 1 2 0 0.0002 8 0 0 0 3.48E+07 2.74E+07 - - - 2.3999 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.20960.20960.2 0.00328 14-Jul R.TLFGFLGK[136.11].L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 889.5153 1.27 34963 20960 2 889.515122 445.7649 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3856.7 - 8.33E+06 - - - -0.1889 - 1.514 0.397 - 148.4 1 2 0 -0.0002 8 0 0 0 3.48E+07 2.74E+07 - - - 3.2241 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.20962.20962.2 0.000101 13/20 R.FDEISFVNFAR.G sp|Q08945|SSRP1_HUMAN 1 1343.651 1.2 34965 20962 2 1343.656351 672.8328 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3856.9 - 5.93E+06 - - - 3.9817 - 2.068 0.389 - 468.8 1 2 0 0.0053 11 0 0 0 1.53E+07 1.28E+07 - - - 3.878 1 230117_WJC_METTL3_WT_vs_EV_F04.20963.20963.2 7.00E-06 14/20 R.PLEVFMC[160.03]SVLK.R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1321.6774 -1 34966 20963 2 1321.676909 661.846 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.38 3856.9 - 5.50E+06 - - - -0.3836 - 2.672 0.619 - 684 1 1 0 -0.0005 11 0 0 0 0.00E+00 0.00E+00 - - - 6.2716 1 230117_WJC_METTL3_WT_vs_EV_F04.20964.20964.3 1.71E-10 15/52 K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 14.38 34967 20964 3 1613.802195 538.941 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3857 - 4.84E+06 - - - 0.681 - 3.153 0.527 - 352.6 1 2 0 0.0011 14 0 0 0 1.07E+08 7.47E+06 - - - 7.467 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20965.20965.2 0.00176 16-Aug R.DIVQFVPFR.E "sp|Q96FN4|CPNE2_HUMAN,sp|O75131|CPNE3_HUMAN,sp|O95741|CPNE6_HUMAN,sp|Q86YQ8|CPNE8_HUMAN,sp|Q8IYJ1|CPNE9_HUMAN,sp|Q9UBL6|CPNE7_HUMAN,sp|Q9HCH3|CPNE5_HUMAN,sp|Q96A23|CPNE4_HUMAN,tr|E7ENV7|E7ENV7_HUMAN" 9 1119.6077 2.35 34968 20965 2 1119.608951 560.8111 Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3 5.84 3857.1 - 4.41E+06 - - - 1.1352 - 1.674 0.444 - 286.5 1 2 0 0.0013 9 0 0 0 1.29E+07 5.51E+06 - - - 3.8105 1 230117_WJC_METTL3_WT_vs_EV_F04.20966.20966.2 2.84E-05 13/20 R.PLEVFMC[160.03]SVLK[136.11].R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1329.6916 2.54 34969 20966 2 1329.691441 665.8531 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.38 3857.2 - 4.03E+06 - - - -0.1316 - 2.606 0.578 - 543.9 1 1 0 -0.0002 11 0 0 0 3.33E+07 1.31E+07 - - - 5.9012 1 230117_WJC_METTL3_WT_vs_EV_F04.20967.20967.2 2.10E-07 15/26 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 3.98 34970 20967 2 1535.790638 768.9025 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3857.3 - 4.02E+06 - - - 0.069 - 2.548 0.519 - 643.6 1 2 0 0.0001 14 0 0 0 8.79E+07 2.21E+07 - - - 5.2214 0.8746 230117_WJC_METTL3_WT_vs_EV_F04.20968.20968.2 0.0107 14-Jul F.LFLWVTGR.A sp|Q86U44|MTA70_HUMAN 1 990.5651 999 34971 20968 2 990.565091 496.2898 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.75 3857.4 - 4.00E+06 - - - 0.004 - 1.418 0.282 - 148.7 1 1 0 0 8 0 0 0 1.03E+07 0.00E+00 - - - 2.1772 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20971.20971.2 0.247 13/20 K.LEDVLPLAFTR[166.11].L "sp|Q5SSJ5|HP1B3_HUMAN,tr|B0QZK4|B0QZK4_HUMAN,tr|Q5SWC8|Q5SWC8_HUMAN" 3 1282.7161 0.7 34974 20971 2 1282.717089 642.3653 Heterochromatin protein 1-binding protein 3 OS=Homo sapiens OX=9606 GN=HP1BP3 PE=1 SV=1 4.37 3857.7 - 3.25E+06 - - - 0.8038 - 2.439 0.331 - 616.3 1 2 0 0.001 11 0 0 0 9.93E+06 1.41E+07 - - - 3.8974 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20972.20972.2 2.56E-05 13/20 K.LEDVLPLAFTR.L "sp|Q5SSJ5|HP1B3_HUMAN,tr|B0QZK4|B0QZK4_HUMAN,tr|Q5SWC8|Q5SWC8_HUMAN" 3 1272.7078 0.7 34975 20972 2 1272.708087 637.3612 Heterochromatin protein 1-binding protein 3 OS=Homo sapiens OX=9606 GN=HP1BP3 PE=1 SV=1 4.37 3857.8 - 2.66E+06 - - - 0.2349 - 2.422 0.341 - 626.1 1 2 0 0.0003 11 0 0 0 9.93E+06 1.41E+07 - - - 3.9526 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.20973.20973.2 0.00157 16-Nov R.DIVQFVPFR[166.11].E "sp|Q96FN4|CPNE2_HUMAN,sp|O75131|CPNE3_HUMAN,sp|O95741|CPNE6_HUMAN,sp|Q86YQ8|CPNE8_HUMAN,sp|Q8IYJ1|CPNE9_HUMAN,sp|Q9UBL6|CPNE7_HUMAN,sp|Q9HCH3|CPNE5_HUMAN,sp|Q96A23|CPNE4_HUMAN,tr|E7ENV7|E7ENV7_HUMAN" 9 1129.616 -1 34976 20973 2 1129.61618 565.8153 Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3 5.84 3857.9 - 2.27E+06 - - - 0.2036 - 2.129 0.421 - 540.4 1 2 0 0.0002 9 0 0 0 0.00E+00 0.00E+00 - - - 4.3366 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.20976.20976.2 0.000933 14-Sep R.VFLWGSFR[166.11].D "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1020.5421 1 34979 20976 2 1020.542568 511.2783 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 9.72 3858.3 - 2.03E+06 - - - 0.5007 - 1.595 0.353 - 403.6 1 2 0 0.0005 8 0 0 0 8.21E+06 8.21E+06 - - - 3.0562 0.999 230117_WJC_METTL3_WT_vs_EV_F04.20980.20980.2 0.266 14-Aug K.VALLDVFR[166.11].E "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 941.5574 2.78 34982 20980 2 941.557675 471.786 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.81 3858.6 - 5.70E+06 - - - 0.3218 - 1.866 0.233 - 324.3 1 2 0 0.0003 8 0 0 0 6.99E+07 2.52E+07 - - - 2.6432 1 230117_WJC_METTL3_WT_vs_EV_F04.20981.20981.2 0.00109 22-Dec K.TLGVDLVALATR[166.11].V "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1237.727 3.82 34983 20981 2 1237.729627 619.8708 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.5 3858.7 - 5.02E+06 - - - 2.1572 - 2.402 0.478 - 441.6 1 2 0 0.0027 12 0 0 0 9.38E+07 2.45E+07 - - - 4.8764 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.20983.20983.3 1.48E-05 13/52 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 5.04 34985 20983 3 1535.792242 512.9375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3858.8 - 4.08E+06 - - - 1.1134 - 2.435 0.464 - 284 1 2 0 0.0017 14 0 0 0 2.02E+07 4.01E+06 - - - 6.0777 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20986.20986.2 4.42E-05 26-Sep K.TFAPEEISAMVLTK[136.11].M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1543.8047 3.98 34988 20986 2 1543.806628 772.9096 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3859 - 2.21E+06 - - - 1.2281 - 1.821 0.448 - 189.8 1 2 0 0.0019 14 0 0 0 8.79E+07 2.21E+07 - - - 3.8535 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20987.20987.2 1.30E-06 26-Sep K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 14.65 34989 20987 2 1621.819505 811.9149 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3859 - 1.77E+06 - - - 2.5952 - 1.9 0.446 - 151.5 1 2 0 0.0042 14 0 0 0 6.46E+08 4.41E+07 - - - 3.9445 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.20988.20988.2 0.0259 20-Dec R.DSLIFLVDASK[136.11].A sp|P12956|XRCC6_HUMAN 1 1214.6638 0.9 34990 20988 2 1214.668367 608.3392 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.21 3859.1 - 1.71E+06 - - - 3.7566 - 2.186 0.34 - 397.4 1 2 0 0.0046 11 0 0 0 3.23E+07 3.57E+07 - - - 3.6665 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.20989.20989.2 1.02E-05 20-Oct K.DFPLSGYVELR.Y sp|O75489|NDUS3_HUMAN 1 1294.6558 -1 34991 20989 2 1294.656091 648.3352 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 4.37 3859.2 - 1.47E+06 - - - 0.2618 - 1.819 0.4 - 338.2 1 2 0 0.0003 11 0 0 0 0.00E+00 0.00E+00 - - - 3.6138 1 230117_WJC_METTL3_WT_vs_EV_F04.20990.20990.2 3.32E-05 28-Nov K.VILESEVIAEAVGVK.K sp|O15226|NKRF_HUMAN 1 1554.8869 1.15 34992 20990 2 1554.891654 778.4507 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.25 3859.3 - 1.29E+06 - - - 3.0735 - 2.402 0.531 - 264.9 1 2 0 0.0048 15 0 0 0 2.95E+07 2.56E+07 - - - 5.1159 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.20991.20991.2 0.162 16-Sep R.DLLFQALGR[166.11].T sp|Q9NSD9|SYFB_HUMAN 1 1041.5847 3.78 34993 20991 2 1041.586453 521.7996 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 5.84 3859.3 - 1.22E+06 - - - 1.731 - 1.644 0.252 - 245.1 1 2 0 0.0018 9 0 0 0 3.00E+07 7.92E+06 - - - 2.3399 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.20993.20993.2 0.00145 14-Aug R.FFFNLGVK[136.11].A sp|Q01804|OTUD4_HUMAN 1 978.5418 2.34 34995 20993 2 978.543168 490.2782 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 8.75 3859.6 - 1.12E+06 - - - 1.3581 - 1.344 0.372 - 140.6 1 2 0 0.0013 8 0 0 0 8.55E+06 3.65E+06 - - - 2.6798 1 230117_WJC_METTL3_WT_vs_EV_F04.20994.20994.2 7.21E-06 16-Oct K.YPENFFLLR.G "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|C9J9S3|C9J9S3_HUMAN,tr|E7ETD8|E7ETD8_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 12 1197.6182 1.45 34996 20994 2 1197.619345 599.8164 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 6 3859.7 - 1.11E+06 - - - 0.9185 - 2.066 0.502 - 494.1 1 2 0 0.0011 9 0 0 0 4.96E+06 3.43E+06 - - - 4.8477 1 230117_WJC_METTL3_WT_vs_EV_F04.20996.20996.2 2.44E-05 14/22 R.LGLQNDLFSLAR[166.11].A "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1355.7437 -1 34998 20996 2 1355.747021 678.8791 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.84 3859.9 - 1.00E+06 - - - 2.4717 - 2.844 0.435 - 754.5 1 2 0 0.0034 12 0 0 0 0.00E+00 0.00E+00 - - - 5.003 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.20997.20997.2 2.10E-05 20-Oct K.DFPLSGYVELR[166.11].Y sp|O75489|NDUS3_HUMAN 1 1304.664 1.99 34999 20997 2 1304.665595 653.3393 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 4.37 3860.1 - 918567 - - - 1.2057 - 1.92 0.503 - 289.7 1 2 0 0.0016 11 0 0 0 6.02E+06 3.02E+06 - - - 4.5204 1 230117_WJC_METTL3_WT_vs_EV_F04.21002.21002.2 3.44E-05 20-Dec R.DSLIFLVDASK.A sp|P12956|XRCC6_HUMAN 1 1206.6496 0.9 35003 21002 2 1206.650824 604.3321 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.21 3860.5 - 760219 - - - 1.0111 - 2.435 0.439 - 459.4 1 2 0 0.0012 11 0 0 0 3.23E+07 3.57E+07 - - - 4.6906 1 230117_WJC_METTL3_WT_vs_EV_F04.21004.21004.2 5.84E-10 19/28 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 3.55 35005 21004 2 1700.90121 851.4565 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3860.7 - 358295 - - - 1.5921 - 3.482 0.638 - 1001.6 1 2 0 0.0027 15 0 0 0 2.56E+08 7.21E+07 - - - 6.8197 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.21007.21007.2 0.00935 14-Jul R.FFFNLGVK.A sp|Q01804|OTUD4_HUMAN 1 970.5276 2.78 35008 21007 2 970.530032 486.2711 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 8.75 3861 - 89180 - - - 2.4657 - 1.394 0.377 - 91.7 1 2 0 0.0024 8 0 0 0 1.14E+07 4.08E+06 - - - 2.8266 0.9743 230117_WJC_METTL3_WT_vs_EV_F04.21009.21009.2 0.99 20-Jul R.ILEFIAVSQLR.G "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN,tr|K7ER27|K7ER27_HUMAN" 4 1287.7551 -1 35010 21009 2 1287.759716 644.8848 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 6 3861.2 - 146857 - - - 3.6055 - 1.118 0.156 - 102.4 1 2 0 0.0046 11 0 0 0 0.00E+00 0.00E+00 - - - 0.4935 1 230117_WJC_METTL3_WT_vs_EV_F04.21020.21020.2 3.41E-07 18/28 R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 3.55 35019 21020 2 1710.90736 856.4607 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3862.4 - 5.78E+06 - - - 0.3437 - 3.47 0.57 - 922.3 1 2 0 0.0006 15 0 0 0 2.56E+08 7.21E+07 - - - 6.3096 1 230117_WJC_METTL3_WT_vs_EV_F04.21021.21021.2 2.00E-05 26-Nov K.LFIYNPTTGEFLGR.T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1626.8406 1.38 35020 21021 2 1626.839918 814.4276 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3862.4 - 5.36E+06 - - - -0.4149 - 2.075 0.562 - 300.7 1 2 0 -0.0007 14 0 0 0 2.67E+07 1.94E+07 - - - 5.0235 1 230117_WJC_METTL3_WT_vs_EV_F04.21022.21022.3 1.59E-07 Nov-56 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 4.45 35021 21022 3 1700.900669 567.9734 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3862.5 - 3.76E+06 - - - 1.274 - 2.411 0.504 - 201.7 1 2 0 0.0022 15 0 0 0 5.61E+07 1.26E+07 - - - 6.4549 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21023.21023.2 6.35E-05 26-Nov K.LFIYNPTTGEFLGR[166.11].T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1636.8489 1.41 35022 21023 2 1636.849581 819.4317 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3862.5 - 3.67E+06 - - - 0.4386 - 1.743 0.501 - 327.6 1 2 0 0.0007 14 0 0 0 2.67E+07 1.90E+07 - - - 4.1354 1 230117_WJC_METTL3_WT_vs_EV_F04.21024.21024.2 3.50E-06 13/22 R.LEGLTDEINFLR.Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1418.7405 1.55 35023 21024 2 1418.741322 710.3775 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3862.6 - 3.43E+06 - - - 0.5477 - 2.709 0.531 - 775.5 1 2 0 0.0008 12 0 0 0 2.10E+07 1.35E+07 - - - 5.5849 0.9623 230117_WJC_METTL3_WT_vs_EV_F04.21025.21025.2 1.97 22-Jun R.TNVINEILSTER[166.11].D "sp|Q9NR80|ARHG4_HUMAN,tr|A0A0C4DFY6|A0A0C4DFY6_HUMAN,tr|A0A087X0P1|A0A087X0P1_HUMAN,tr|E9PEM0|E9PEM0_HUMAN,tr|E7EV07|E7EV07_HUMAN" 5 1397.739 0.76 35024 21025 2 1397.739116 699.8768 Rho guanine nucleotide exchange factor 4 OS=Homo sapiens OX=9606 GN=ARHGEF4 PE=1 SV=3 4.53 3862.6 - 2.77E+06 - - - 0.0987 - 1.358 0.012 - 85.8 2 2 0 0.0001 12 0 0 0 6.38E+06 8.38E+06 - - - -0.1997 1 230117_WJC_METTL3_WT_vs_EV_F04.21026.21026.2 1.17E-06 19/28 K.VSALDLAVLDQVEAR.L "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 6 1597.8675 9.23 35025 21026 2 1597.86971 799.941 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.03 3862.7 - 2.31E+06 - - - 1.3606 - 3.382 0.423 - 1505 1 2 0 0.0022 15 0 0 0 7.13E+06 7.73E+05 - - - 5.1603 1 230117_WJC_METTL3_WT_vs_EV_F04.21028.21028.2 1.38E-06 18-Nov R.WYEWLDPSIK.K sp|Q99459|CDC5L_HUMAN 1 1335.6499 1.18 35027 21028 2 1335.650653 668.8322 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3862.9 - 1.78E+06 - - - 0.5346 - 2.022 0.485 - 382.6 1 2 0 0.0007 10 0 0 0 1.82E+07 1.54E+07 - - - 4.5883 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21029.21029.2 0.000131 26-Dec R.VLLATLSIPITPER.T sp|Q14152|EIF3A_HUMAN 1 1521.913 0.96 35028 21029 2 1521.912358 761.9638 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3863 - 960612 - - - -0.4415 - 2.302 0.428 - 233.9 1 2 0 -0.0007 14 0 0 0 1.07E+07 1.11E+07 - - - 4.2943 1 230117_WJC_METTL3_WT_vs_EV_F04.21031.21031.2 1.41E-09 16/28 K.LLDTVDDMLANDIAR.L "sp|Q9H4M9|EHD1_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 3 1673.8294 2.96 35030 21031 2 1673.830326 837.922 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 3.77 3863.1 - 821488 - - - 0.5317 - 3.203 0.661 - 1091.6 1 2 0 0.0009 15 0 0 0 2.34E+06 7.93E+05 - - - 6.7848 1 230117_WJC_METTL3_WT_vs_EV_F04.21032.21032.2 4.00E-05 26-Dec R.VFGAPEVLENLEVK[136.11].S sp|Q8TEM1|PO210_HUMAN 1 1550.8436 1.78 35031 21032 2 1550.843454 776.4291 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.25 3863.2 - 737968 - - - -0.0683 - 2.335 0.519 - 350.9 1 2 0 -0.0001 14 0 0 0 7.25E+06 4.08E+06 - - - 5.0023 0.8616 230117_WJC_METTL3_WT_vs_EV_F04.21034.21034.2 3.55E-05 14/20 F.PEEISSMVLTK.M "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1232.6322 0.22 35033 21034 2 1232.638611 617.3234 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.53 3863.4 - 386700 - - - 5.1686 - 2.736 0.375 - 725.7 1 1 0 0.0064 11 0 0 0 1.58E+06 7.16E+06 - - - 4.5316 1 230117_WJC_METTL3_WT_vs_EV_F04.21037.21037.2 2.54E-06 13/22 R.LEGLTDEINFLR[166.11].Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1428.7488 1.55 35034 21037 2 1428.747111 715.3817 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3863.8 - 1.59E+06 - - - -1.1927 - 2.753 0.527 - 737.4 1 2 0 -0.0017 12 0 0 0 2.09E+07 1.35E+07 - - - 5.5974 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.21040.21040.2 0.00461 18-Sep K.FSLFAGGMLR.V sp|Q9BVK6|TMED9_HUMAN 1 1097.5692 1.06 35037 21040 2 1097.568031 549.7919 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 9.75 3864.3 - 585987 - - - -1.0523 - 1.976 0.401 - 265.6 1 2 0 -0.0012 10 0 0 0 5.91E+06 5.60E+06 - - - 3.9035 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.21041.21041.2 1.36E-05 20-Oct R.GVTFLFPIQAK.T sp|Q9NR30|DDX21_HUMAN 1 1219.6965 0.87 35038 21041 2 1219.696791 610.8555 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3864.4 - 585760 - - - 0.2427 - 2.051 0.314 - 339.6 1 2 0 0.0003 11 0 0 0 4.61E+07 5.28E+07 - - - 3.3034 1 230117_WJC_METTL3_WT_vs_EV_F04.21042.21042.2 3.31E-06 13/24 R.APLPDLYPFGTMR.G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1476.7435 1.78 35039 21042 2 1476.741085 739.379 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3864.5 - 424377 - - - -1.6503 - 2.26 0.529 - 544.8 1 2 0 -0.0024 13 0 0 0 3.30E+06 1.85E+06 - - - 5.0401 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21044.21044.2 7.61E-05 22-Oct R.VTGVPLSYLLSR.G "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1303.75 2.99 35041 21044 2 1303.749906 652.8823 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.72 3864.8 - 375796 - - - -0.0621 - 1.891 0.353 - 220.7 1 2 0 -0.0001 12 0 0 0 2.74E+06 9.19E+05 - - - 3.3246 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.21045.21045.2 0.00193 14-Aug R.FPLFGGWK[136.11].T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 958.5156 1.66 35042 21045 2 958.514345 480.2651 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3864.9 - 323005 - - - -1.3344 - 1.517 0.443 - 200.3 1 2 0 -0.0013 8 0 0 0 1.56E+07 9.37E+06 - - - 3.5694 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21046.21046.2 0.00598 24-Oct R.APLPDLYPFGTMR[166.11].G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1486.7518 2.21 35043 21046 2 1486.753414 744.3832 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3865 - 204374 - - - 1.091 - 1.971 0.459 - 332.8 1 2 0 0.0016 13 0 0 0 7.64E+06 3.46E+06 - - - 4.1722 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21047.21047.3 0.419 13/44 R.LLALLDALASHK.A "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 1263.7551 2.13 35044 21047 3 1263.754032 422.259 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6.74 3865.1 - 199654 - - - -0.8237 - 2.843 0.322 - 279.8 1 2 0 -0.001 12 0 0 0 2.60E+06 1.22E+06 - - - 5.0259 0.9911 230117_WJC_METTL3_WT_vs_EV_F04.21048.21048.2 0.0605 14-Jun R.EGLLAIFK[136.11].S "sp|P35222|CTNB1_HUMAN,sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|C9J826|C9J826_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 15 897.5415 6.61 35045 21048 2 897.539331 449.778 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 6.1 3865.3 - 197769 - - - -2.4211 - 1.376 0.283 - 110.4 1 2 0 -0.0022 8 0 0 0 1.13E+07 1.71E+06 - - - 2.0932 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.21051.21051.2 0.000508 20-Nov K.ISDFGLATVFR[166.11].Y "sp|O14757|CHK1_HUMAN,tr|E9PKQ3|E9PKQ3_HUMAN,tr|E9PPA5|E9PPA5_HUMAN,tr|E9PJI4|E9PJI4_HUMAN,tr|E7EPP6|E7EPP6_HUMAN" 5 1234.6585 0.58 35048 21051 2 1234.661796 618.3365 Serine\threonine-protein kinase Chk1 OS=Homo sapiens OX=9606 GN=CHEK1 PE=1 SV=2 5.84 3865.7 - 167517 - - - 2.6347 - 2.02 0.179 - 263.2 1 2 0 0.0033 11 0 0 0 4.89E+06 8.46E+06 - - - 2.2641 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21056.21056.3 0.000124 Oct-44 R.LLALLDALASHK[136.11].A "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 1271.7693 2.13 35053 21056 3 1271.767877 424.9304 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6.74 3866.3 - 110452 - - - -1.0977 - 1.854 0.422 - 161.1 1 2 0 -0.0014 12 0 0 0 2.52E+06 1.18E+06 - - - 4.9557 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21060.21060.2 0.102 20-Oct K.SGAYLIPLLER[166.11].L "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1240.7055 1.34 35056 21060 2 1240.707187 621.36 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.72 3866.7 - 2.33E+06 - - - 1.3654 - 1.929 0.274 - 364.4 1 2 0 0.0017 11 0 0 0 1.04E+08 7.75E+07 - - - 2.8416 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21061.21061.2 0.000802 18-Oct K.FEELNMDLFR.S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1312.6122 3.32 35057 21061 2 1312.612714 657.3134 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.14 3866.8 - 2.08E+06 - - - 0.4122 - 2.193 0.417 - 374.4 1 2 0 0.0005 10 0 0 0 1.43E+07 4.31E+06 - - - 4.3127 1 230117_WJC_METTL3_WT_vs_EV_F04.21064.21064.3 6.11E-07 15/52 K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 14.38 35060 21064 3 1621.816761 541.6124 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3867.1 - 1.32E+06 - - - 0.9033 - 2.623 0.567 - 272.2 1 2 0 0.0015 14 0 0 0 1.07E+08 7.47E+06 - - - 7.4238 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.21066.21066.2 0.0138 14-Jul K.FYSFLVLK.K "sp|Q9H4I0|RD21L_HUMAN,sp|O60216|RAD21_HUMAN,tr|A0A804HJ87|A0A804HJ87_HUMAN,tr|E5RI01|E5RI01_HUMAN,tr|E5RG18|E5RG18_HUMAN,tr|E5RFZ5|E5RFZ5_HUMAN" 6 1015.5743 2.17 35062 21066 2 1015.575576 508.7944 Double-strand-break repair protein rad21-like protein 1 OS=Homo sapiens OX=9606 GN=RAD21L1 PE=2 SV=3 8.59 3867.3 - 819389 - - - 1.3007 - 1.449 0.371 - 113 1 2 0 0.0013 8 0 0 0 1.59E+07 7.35E+06 - - - 2.8993 0.9009 230117_WJC_METTL3_WT_vs_EV_F04.21067.21067.2 0.0349 12-May Y.SSFLFWR.M sp|Q13015|AF1Q_HUMAN 1 941.4759 5.52 35063 21067 2 941.475511 471.7452 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 9.47 3867.4 - 784199 - - - -0.4535 - 1.209 0.421 - 117.2 1 1 0 -0.0004 7 0 0 0 2.35E+06 4.26E+05 - - - 2.7517 1 230117_WJC_METTL3_WT_vs_EV_F04.21070.21070.2 0.0429 16/24 M.PGIVELPTLEELK.V sp|P51970|NDUA8_HUMAN 1 1436.8126 2.04 35066 21070 2 1436.811428 719.4136 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 4.25 3867.8 - 269371 - - - -0.8484 - 3.052 0.481 - 768.7 1 2 0 -0.0012 13 0 0 0 2.30E+06 1.13E+06 - - - 5.457 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21073.21073.2 3.19E-05 24-Nov M.PGIVELPTLEELK[136.11].V sp|P51970|NDUA8_HUMAN 1 1444.8268 1.89 35069 21073 2 1444.828676 723.4207 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 4.25 3868.2 - 226201 - - - 1.2659 - 2.047 0.33 - 141.1 1 2 0 0.0018 13 0 0 0 2.14E+06 1.13E+06 - - - 3.3164 0.994 230117_WJC_METTL3_WT_vs_EV_F04.21074.21074.2 1.09E-05 30-Jul R.VFVPLPGSTVMLC[160.03]DYK.F sp|Q5SWX8|ODR4_HUMAN 1 1824.9154 -1 35070 21074 2 1824.908314 913.465 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 5.8 3868.3 - 0 - - - -3.8911 - 1.666 0.47 - 84.6 1 2 0 -0.0071 16 0 0 0 0.00E+00 0.00E+00 - - - 3.7651 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21076.21076.2 0.000199 20-Dec R.GVTFLFPIQAK[136.11].T sp|Q9NR30|DDX21_HUMAN 1 1227.7107 0.94 35071 21076 2 1227.711761 614.8626 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3868.5 - 1.81E+06 - - - 0.8683 - 2.116 0.295 - 473.9 1 2 0 0.0011 11 0 0 0 4.58E+07 4.86E+07 - - - 3.2472 0.9914 230117_WJC_METTL3_WT_vs_EV_F04.21078.21078.3 0.0877 14/56 R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 4.42 35072 21078 3 1710.902284 571.3095 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3868.8 - 5.95E+06 - - - -2.6232 - 1.825 0.261 - 222.2 1 2 0 -0.0045 15 0 0 0 5.57E+07 1.26E+07 - - - 3.0184 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21080.21080.2 0.00409 14-Sep R.FPLFGGWK.T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 950.5014 1.66 35074 21080 2 950.502221 476.258 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3869 - 1.79E+06 - - - 0.8385 - 1.593 0.338 - 315.1 1 2 0 0.0008 8 0 0 0 3.15E+07 1.90E+07 - - - 2.9415 0.9975 230117_WJC_METTL3_WT_vs_EV_F04.21083.21083.2 0.00275 18-Aug R.YVLGMQELFR[166.11].G "sp|Q96J01|THOC3_HUMAN,tr|D6RGZ2|D6RGZ2_HUMAN" 2 1264.6513 0.67 35077 21083 2 1264.649987 633.333 THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1 6 3869.3 - 329564 - - - -1.077 - 1.676 0.278 - 200.5 1 2 0 -0.0014 10 0 0 0 3.45E+06 5.19E+06 - - - 2.5353 1 230117_WJC_METTL3_WT_vs_EV_F04.21084.21084.2 2.03E-06 15/26 R.DYGVLLEGSGLALR[166.11].G sp|P30048|PRDX3_HUMAN 1 1471.791 1.2 35078 21084 2 1471.791213 736.9028 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 4.37 3869.5 - 320920 - - - 0.1352 - 2.937 0.539 - 735.5 1 2 0 0.0002 14 0 0 0 3.96E+06 3.29E+06 - - - 5.7256 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.21085.21085.2 0.00816 18-Aug K.C[160.03]PFLIPFETR.Q "sp|Q9ULT8|HECD1_HUMAN,tr|H0YJD4|H0YJD4_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN" 3 1278.6431 2.04 35079 21085 2 1278.645028 640.3288 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 5.99 3869.6 - 295323 - - - 1.5235 - 1.835 0.242 - 193.6 1 2 0 0.0019 10 0 0 0 1.36E+06 6.68E+05 - - - 2.5222 1 230117_WJC_METTL3_WT_vs_EV_F04.21088.21088.2 0.000682 14/26 R.IADQFLGAMYTLPR.Q "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN,tr|R4GMP9|R4GMP9_HUMAN" 3 1594.8177 999 35082 21088 2 1594.818743 798.4162 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 5.84 3870 - 205637 - - - 0.6233 - 2.854 0.475 - 620.2 1 2 0 0.001 14 0 0 0 1.41E+06 0.00E+00 - - - 5.1808 1 230117_WJC_METTL3_WT_vs_EV_F04.21092.21092.2 2.98E-07 26-Dec R.ILGIPVIVTEQYPK.G "sp|Q96CN7|ISOC1_HUMAN,tr|D6RGE2|D6RGE2_HUMAN" 2 1568.9178 1.22 35086 21092 2 1568.920094 785.4662 Isochorismatase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ISOC1 PE=1 SV=3 6 3870.5 - 118953 - - - 1.4743 - 2.101 0.599 - 362.8 1 2 0 0.0023 14 0 0 0 1.48E+06 1.22E+06 - - - 5.3275 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21098.21098.2 0.000212 14-Aug R.GFVFITFK[136.11].E "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 965.5466 0.81 35090 21098 2 965.547486 483.7806 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3871.4 - 1.37E+06 - - - 0.928 - 1.612 0.448 - 289 1 2 0 0.0009 8 0 0 0 1.52E+07 1.88E+07 - - - 3.7897 1 230117_WJC_METTL3_WT_vs_EV_F04.21099.21099.2 2.08E-07 15/26 R.VLLATLSIPITPER[166.11].T sp|Q14152|EIF3A_HUMAN 1 1531.9213 0.97 35091 21099 2 1531.922797 766.9679 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3871.5 - 1.10E+06 - - - 0.9772 - 2.947 0.472 - 701.6 1 2 0 0.0015 14 0 0 0 1.29E+07 1.34E+07 - - - 5.2389 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21102.21102.2 0.00111 16-Sep R.IIFVDEVFK.L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1108.6168 6.57 35094 21102 2 1108.619833 555.3157 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 4.37 3871.8 - 559724 - - - 2.6925 - 1.843 0.434 - 176.6 1 2 0 0.003 9 0 0 0 2.90E+07 4.42E+06 - - - 4.0144 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21103.21103.2 0.000864 14-Sep K.FYSFLVLK[136.11].K "sp|Q9H4I0|RD21L_HUMAN,sp|O60216|RAD21_HUMAN,tr|A0A804HJ87|A0A804HJ87_HUMAN,tr|E5RI01|E5RI01_HUMAN,tr|E5RG18|E5RG18_HUMAN,tr|E5RFZ5|E5RFZ5_HUMAN" 6 1023.5885 2.17 35095 21103 2 1023.590684 512.8015 Double-strand-break repair protein rad21-like protein 1 OS=Homo sapiens OX=9606 GN=RAD21L1 PE=2 SV=3 8.59 3872 - 542480 - - - 2.1776 - 1.442 0.395 - 186.8 1 2 0 0.0022 8 0 0 0 1.59E+07 7.35E+06 - - - 3.0617 1 230117_WJC_METTL3_WT_vs_EV_F04.21104.21104.2 0.00658 14/20 K.LSDLDYMQFIR.L sp|P82933|RT09_HUMAN 1 1399.6806 1.38 35096 21104 2 1399.683224 700.8476 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.21 3872.1 - 468310 - - - 1.884 - 3.019 0.416 - 1174.4 1 2 0 0.0026 11 0 0 0 4.24E+06 3.07E+06 - - - 5.1018 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21107.21107.2 0.00238 20-Oct K.LSDLDYMQFIR[166.11].L sp|P82933|RT09_HUMAN 1 1409.6889 1.38 35099 21107 2 1409.688728 705.8517 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.21 3872.5 - 382356 - - - -0.0915 - 2.548 0.359 - 498.3 1 2 0 -0.0001 11 0 0 0 4.24E+06 3.07E+06 - - - 4.2228 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21108.21108.2 0.00072 18-Sep K.FEELNMDLFR[166.11].S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1322.6204 4.62 35100 21108 2 1322.621891 662.3175 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.14 3872.6 - 334271 - - - 1.0948 - 1.968 0.328 - 262.9 1 2 0 0.0014 10 0 0 0 1.41E+07 3.06E+06 - - - 3.3529 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21110.21110.2 0.0102 16-Sep R.IIFVDEVFK[136.11].L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1116.631 6.77 35102 21110 2 1116.632789 559.3228 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 4.37 3872.9 - 318214 - - - 1.5592 - 1.758 0.351 - 160.2 1 2 0 0.0017 9 0 0 0 2.90E+07 4.29E+06 - - - 3.2651 0.997 230117_WJC_METTL3_WT_vs_EV_F04.21114.21114.2 0.224 20-Jun R.VWIPDPDEVWR[166.11].S sp|Q9ULV0|MYO5B_HUMAN 1 1420.7015 2.92 35106 21114 2 1420.704066 711.358 Unconventional myosin-Vb OS=Homo sapiens OX=9606 GN=MYO5B PE=1 SV=3 4.03 3873.4 - 111613 - - - 1.8266 - 1.327 0.218 - 105.3 1 2 0 0.0026 11 0 0 0 2.48E+06 8.50E+05 - - - 1.4157 1 230117_WJC_METTL3_WT_vs_EV_F04.21121.21121.3 3.85E-05 14/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 35110 21121 3 1603.766071 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3874.2 - 9.61E+06 - - - 1.3287 - 2.481 0.553 - 273.9 1 2 0 0.0021 12 0 0 0 6.51E+07 0.00E+00 - - - 7.2235 1 230117_WJC_METTL3_WT_vs_EV_F04.21128.21128.2 1.64E-05 24-Dec R.ELPTAFDYVEFTR[166.11].S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1596.7699 1.17 35117 21128 2 1596.773952 799.3922 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.14 3875.1 - 690900 - - - 2.5101 - 2.492 0.514 - 689.7 1 2 0 0.004 13 0 0 0 1.26E+07 1.08E+07 - - - 5.1796 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21130.21130.2 0.0079 20-Sep K.NVPGLAILLSK.D sp|Q9BUL9|RPP25_HUMAN 1 1123.6965 1.36 35119 21130 2 1123.697326 562.8555 Ribonuclease P protein subunit p25 OS=Homo sapiens OX=9606 GN=RPP25 PE=1 SV=1 8.75 3875.4 - 594875 - - - 0.7395 - 1.573 0.343 - 182.2 1 2 0 0.0008 11 0 0 0 8.28E+06 6.08E+06 - - - 2.7996 1 230117_WJC_METTL3_WT_vs_EV_F04.21131.21131.2 5.98E-09 22-Dec K.VDALMDEINFMK.M "sp|P13647|K2C5_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 2 1424.668 999 35120 21131 2 1424.668247 713.3413 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.03 3875.5 - 583921 - - - 0.1923 - 2.696 0.641 - 490.6 1 2 0 0.0003 12 0 0 0 5.34E+07 0.00E+00 - - - 6.3849 1 230117_WJC_METTL3_WT_vs_EV_F04.21132.21132.2 1.24E-08 15/26 R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 17.75 35121 21132 2 1581.809674 791.9109 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3875.7 - 548850 - - - 1.5362 - 3.148 0.621 - 610.1 1 2 0 0.0024 14 0 0 0 2.25E+07 1.27E+06 - - - 6.5047 1 230117_WJC_METTL3_WT_vs_EV_F04.21134.21134.2 3.53E-07 24-Dec R.ELYAFFGDSLATR.F sp|Q9Y6J9|TAF6L_HUMAN 1 1488.7249 1.01 35123 21134 2 1488.718942 745.3697 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4.37 3875.9 - 442126 - - - -3.9987 - 2.313 0.58 - 461.4 1 2 0 -0.006 13 0 0 0 6.57E+06 6.51E+06 - - - 5.4752 1 230117_WJC_METTL3_WT_vs_EV_F04.21139.21139.2 1.93E-05 Nov-36 R.LAESLLALSQQEELADLPK.D sp|Q9BVJ6|UT14A_HUMAN 1 2067.11 -1 35128 21139 2 2067.10814 1034.5623 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4 3876.6 - 170749 - - - -0.8766 - 2.556 0.539 - 71.4 1 2 0 -0.0018 19 0 0 0 0.00E+00 0.00E+00 - - - 5.3287 1 230117_WJC_METTL3_WT_vs_EV_F04.21144.21144.2 8.79E-08 24-Dec R.LLSFSPEEFPTLK.A sp|Q5JSZ5|PRC2B_HUMAN 1 1506.797 1.21 35132 21144 2 1506.800355 754.4058 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3877.2 - 1.03E+06 - - - 2.2286 - 2.566 0.604 - 462.9 1 2 0 0.0034 13 0 0 0 6.96E+07 5.74E+07 - - - 5.9197 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.21145.21145.2 0.00154 24-Sep R.LLSFSPEEFPTLK[136.11].A sp|Q5JSZ5|PRC2B_HUMAN 1 1514.8112 1.21 35133 21145 2 1514.816229 758.4129 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3877.2 - 717377 - - - 3.3219 - 1.782 0.362 - 188.5 1 2 0 0.005 13 0 0 0 6.96E+07 5.74E+07 - - - 3.1959 0.9861 230117_WJC_METTL3_WT_vs_EV_F04.21147.21147.2 2.02 18-Aug K.DALLLWC[160.03]QMK.T "sp|P11277|SPTB1_HUMAN,sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,sp|Q9H254|SPTN4_HUMAN,tr|C9JY79|C9JY79_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|M0QZQ3|M0QZQ3_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 9 1276.6308 0.95 35135 21147 2 1276.634113 639.3227 "Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB PE=1 SV=5" 5.83 3877.4 - 229090 - - - 2.5951 - 1.337 0.088 - 184.6 1 2 0 0.0033 10 0 0 0 4.19E+06 4.41E+06 - - - 0.5006 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21158.21158.2 0.000918 20-Nov R.SIFTGLMIDPR.T sp|Q8IWA0|WDR75_HUMAN 1 1248.6536 1.56 35144 21158 2 1248.654793 625.3341 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 5.55 3878.6 - 1.20E+06 - - - 0.9202 - 2.082 0.348 - 310.3 1 2 0 0.0011 11 0 0 0 7.63E+06 4.88E+06 - - - 3.5948 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21159.21159.2 0.00084 18-Oct R.LLEVYDQLFK.S "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1266.686 2.3 35145 21159 2 1266.689177 634.3503 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3878.6 - 1.19E+06 - - - 2.516 - 2.277 0.41 - 340.2 1 2 0 0.0032 10 0 0 0 2.42E+07 1.05E+07 - - - 4.3651 1 230117_WJC_METTL3_WT_vs_EV_F04.21162.21162.2 1.99E-07 22-Nov K.LTAYAMTIPFVR.Q "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1381.7428 1.18 35148 21162 2 1381.744565 691.8787 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 3879 - 921924 - - - 1.2824 - 2.309 0.586 - 565.7 1 2 0 0.0018 12 0 0 0 4.72E+06 3.99E+06 - - - 5.5704 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21163.21163.2 0.00154 16-Aug K.AFVPAILFK.D sp|Q9HAU5|RENT2_HUMAN 1 1004.6059 0.99 35149 21163 2 1004.606384 503.3102 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3879.1 - 907411 - - - 0.4927 - 1.704 0.4 - 214.3 1 2 0 0.0005 9 0 0 0 1.07E+07 1.08E+07 - - - 3.5372 1 230117_WJC_METTL3_WT_vs_EV_F04.21165.21165.2 1.49E-06 26-Nov R.ILSVQGTEPLVLFK[136.11].E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1550.9163 1.32 35151 21165 2 1550.917527 776.4654 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3879.4 - 761230 - - - 0.7712 - 2.249 0.513 - 351.4 1 2 0 0.0012 14 0 0 0 2.31E+07 1.74E+07 - - - 4.8635 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21166.21166.2 5.14E-05 16-Jul K.AFVPAILFK[136.11].D sp|Q9HAU5|RENT2_HUMAN 1 1012.6201 0.99 35152 21166 2 1012.620821 507.3173 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3879.5 - 729631 - - - 0.7229 - 1.646 0.452 - 179.4 1 2 0 0.0007 9 0 0 0 1.07E+07 1.08E+07 - - - 3.821 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21167.21167.2 5.63E-05 22-Oct K.LTAYAMTIPFVR[166.11].Q "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1391.7511 1.18 35153 21167 2 1391.752796 696.8828 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 3879.6 - 637751 - - - 1.2452 - 2.104 0.47 - 457.1 1 2 0 0.0017 12 0 0 0 4.72E+06 3.99E+06 - - - 4.469 1 230117_WJC_METTL3_WT_vs_EV_F04.21168.21168.2 0.00153 20-Nov K.NVPGLAILLSK[136.11].D sp|Q9BUL9|RPP25_HUMAN 1 1131.7107 1.32 35154 21168 2 1131.712938 566.8626 Ribonuclease P protein subunit p25 OS=Homo sapiens OX=9606 GN=RPP25 PE=1 SV=1 8.75 3879.7 - 602507 - - - 1.982 - 2.148 0.504 - 310.3 1 2 0 0.0022 11 0 0 0 7.84E+06 5.94E+06 - - - 4.8311 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.21170.21170.3 0.000189 Dec-52 R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 41.44 35156 21170 3 1581.808431 528.2764 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3880 - 448797 - - - 0.7504 - 2.338 0.378 - 178.1 1 2 0 0.0012 14 0 0 0 5.30E+06 1.28E+05 - - - 5.011 1 230117_WJC_METTL3_WT_vs_EV_F04.21174.21174.2 2.56E-06 13/26 K.TGAAGAEALSLLLK.R "sp|Q9P2N6|KANL3_HUMAN,tr|C9J5A4|C9J5A4_HUMAN,tr|A0A590UJ53|A0A590UJ53_HUMAN" 3 1313.7555 3.98 35160 21174 2 1313.75565 657.885 KAT8 regulatory NSL complex subunit 3 OS=Homo sapiens OX=9606 GN=KANSL3 PE=1 SV=2 5.66 3880.5 - 364435 - - - 0.1393 - 2.578 0.441 - 543.7 1 2 0 0.0002 14 0 0 0 7.08E+06 1.78E+06 - - - 4.6747 0.999 230117_WJC_METTL3_WT_vs_EV_F04.21183.21183.2 0.0138 14-Aug R.LQWWDFTK.F "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1122.5498 1.44 35168 21183 2 1122.550603 562.2822 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 5.84 3881.6 - 169300 - - - 0.6877 - 1.453 0.31 - 200.2 1 2 0 0.0008 8 0 0 0 3.35E+06 2.33E+06 - - - 2.4573 1 230117_WJC_METTL3_WT_vs_EV_F04.21185.21185.2 8.78E-06 13/24 R.VVSTFGVIFDPVK.Q sp|Q9P2D1|CHD7_HUMAN 1 1406.781 0.77 35170 21185 2 1406.781374 704.3978 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 5.81 3881.9 - 159860 - - - 0.2993 - 2.445 0.6 - 533.1 1 2 0 0.0004 13 0 0 0 1.41E+07 1.84E+07 - - - 5.7671 1 230117_WJC_METTL3_WT_vs_EV_F04.21192.21192.3 5.77E-07 Aug-40 R.SIIGMIDMFHK.Y "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1290.6464 999 35175 21192 3 1290.647819 431.2228 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.46 3882.7 - 353773 - - - 1.0607 - 1.77 0.576 - 67.8 1 2 0 0.0014 11 0 0 0 1.79E+07 0.00E+00 - - - 6.5835 1 230117_WJC_METTL3_WT_vs_EV_F04.21194.21194.2 4.32E-05 26-Sep R.ILSVQGTEPLVLFK.E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1542.9021 1.32 35177 21194 2 1542.90463 772.4583 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3882.8 - 741698 - - - 1.6197 - 2.205 0.508 - 260.4 1 2 0 0.0025 14 0 0 0 2.31E+07 1.74E+07 - - - 4.7766 1 230117_WJC_METTL3_WT_vs_EV_F04.21195.21195.2 0.000349 18-Oct R.AEVWDLDMLR.S sp|Q6P2E9|EDC4_HUMAN 1 1246.6016 1.47 35178 21195 2 1246.602457 624.3081 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 4.03 3882.9 - 132407 - - - 0.6811 - 2.278 0.444 - 538.9 1 2 0 0.0008 10 0 0 0 6.07E+06 4.14E+06 - - - 4.6182 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21198.21198.2 0.000592 24-Oct R.FGQDIISPLLSVK.E "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V414|A0A7I2V414_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|J3KNG4|J3KNG4_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|G3V5F3|G3V5F3_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|A0A7I2V4B9|A0A7I2V4B9_HUMAN,tr|H0YJY1|H0YJY1_HUMAN,tr|H0YJS6|H0YJS6_HUMAN,tr|G3V363|G3V363_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2V5R9|A0A7I2V5R9_HUMAN,tr|G3V4I1|G3V4I1_HUMAN,tr|A0A7I2V3Y3|A0A7I2V3Y3_HUMAN" 24 1415.8024 1.37 35179 21198 2 1415.803773 708.9085 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 5.84 3883.3 - 2.20E+06 - - - 0.9578 - 1.832 0.396 - 213.6 1 2 0 0.0014 13 0 0 0 2.64E+07 1.93E+07 - - - 3.5192 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.21199.21199.2 0.0138 18-Jul R.LLEVYDQLFK[136.11].S "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1274.7002 2.3 35180 21199 2 1274.702939 638.3574 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3883.4 - 172768 - - - 2.1566 - 1.664 0.271 - 140.9 1 2 0 0.0027 10 0 0 0 2.42E+07 1.05E+07 - - - 2.4631 1 230117_WJC_METTL3_WT_vs_EV_F04.21200.21200.2 3.06E-05 20/26 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.43 35181 21200 2 1672.884688 837.4479 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3883.5 - 340277 - - - 2.0695 - 3.49 0.597 - 1644.9 1 2 0 0.0035 14 0 0 0 3.12E+07 7.24E+07 - - - 6.5859 0.9041 230117_WJC_METTL3_WT_vs_EV_F04.21202.21202.2 0.151 Jun-32 R.ASSGGGAGGAAGYAPVK.Y sp|P25067|CO8A2_HUMAN 1 1376.6684 2.93 35183 21202 2 1376.663662 689.3415 Collagen alpha-2(VIII) chain OS=Homo sapiens OX=9606 GN=COL8A2 PE=1 SV=2 8.63 3883.8 - 234580 - - - -3.4722 - 1.201 0.153 - 57.4 1 2 0 -0.0048 17 0 0 0 3.82E+06 1.31E+06 - - - 0.6199 1 230117_WJC_METTL3_WT_vs_EV_F04.21208.21208.2 1.70E-07 17/26 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.43 35189 21208 2 1662.873888 832.4438 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3884.6 - 134951 - - - 0.5605 - 3.276 0.58 - 1170.4 1 2 0 0.0009 14 0 0 0 3.12E+07 7.24E+07 - - - 6.3024 0.9962 230117_WJC_METTL3_WT_vs_EV_F04.21215.21215.2 0.000755 24-Oct R.LPEYPQVDDLLLR.R "sp|Q9UI10|EI2BD_HUMAN,tr|A0A087WW69|A0A087WW69_HUMAN,tr|A0A087WTA5|A0A087WTA5_HUMAN,tr|F8W8L6|F8W8L6_HUMAN,tr|E7ERK9|E7ERK9_HUMAN,tr|H7C2L8|H7C2L8_HUMAN" 6 1569.8403 2.18 35196 21215 2 1569.849245 785.9274 Translation initiation factor eIF-2B subunit delta OS=Homo sapiens OX=9606 GN=EIF2B4 PE=1 SV=2 4.03 3885.5 - 0 - - - 5.7241 - 1.982 0.424 - 219.3 1 2 0 0.009 13 0 0 0 1.40E+06 6.45E+05 - - - 3.9256 1 230117_WJC_METTL3_WT_vs_EV_F04.21223.21223.3 7.45E-08 20/52 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 1 35202 21223 3 1672.886316 558.6344 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3886.5 - 1.00E+07 - - - 3.0427 - 3.72 0.555 - 733.4 1 2 0 0.0051 14 0 0 0 2.73E+07 2.73E+07 - - - 8.2176 1 230117_WJC_METTL3_WT_vs_EV_F04.21224.21224.3 2.29E-07 18/52 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 1 35203 21224 3 1662.879376 555.2983 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3886.6 - 4.45E+06 - - - 3.8608 - 3.586 0.587 - 488 1 2 0 0.0064 14 0 0 0 2.72E+07 2.71E+07 - - - 8.4765 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.21225.21225.2 0.000993 22-Dec R.GLFIIDPNGVIK.H sp|P30048|PRDX3_HUMAN 1 1284.7442 2.23 35204 21225 2 1284.747516 643.3794 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3886.7 - 2.49E+06 - - - 2.6013 - 2.098 0.358 - 335.1 1 2 0 0.0033 12 0 0 0 1.72E+07 7.73E+06 - - - 3.6338 1 230117_WJC_METTL3_WT_vs_EV_F04.21226.21226.2 4.95E-07 16/22 R.LIMNYLVTEGFK.E sp|Q9NWU2|GID8_HUMAN 1 1426.753 1.1 35205 21226 2 1426.755962 714.3838 Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1 6 3886.8 - 2.06E+06 - - - 2.0592 - 2.61 0.587 - 761.4 1 2 0 0.0029 12 0 0 0 6.63E+06 6.02E+06 - - - 5.8999 1 230117_WJC_METTL3_WT_vs_EV_F04.21227.21227.2 3.91E-07 14/22 R.LIMNYLVTEGFK[136.11].E sp|Q9NWU2|GID8_HUMAN 1 1434.7672 1.1 35206 21227 2 1434.769424 718.3909 Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1 6 3887 - 1.82E+06 - - - 1.5333 - 2.457 0.593 - 534.5 1 2 0 0.0022 12 0 0 0 6.63E+06 6.02E+06 - - - 5.7855 1 230117_WJC_METTL3_WT_vs_EV_F04.21228.21228.2 0.000125 18-Nov K.DAITQALFLR.E sp|Q9UNX4|WDR3_HUMAN 1 1146.6397 0.98 35207 21228 2 1146.641962 574.3271 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.84 3887.1 - 1.70E+06 - - - 1.9657 - 2.431 0.495 - 326.2 1 2 0 0.0023 10 0 0 0 1.21E+07 1.23E+07 - - - 5.1759 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.21230.21230.2 9.25E-06 13/24 K.DAAIYLVTSLASK[136.11].A sp|P55060|XPO2_HUMAN 1 1358.7537 0.82 35209 21230 2 1358.757475 680.3841 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.83 3887.4 - 1.27E+06 - - - 2.7915 - 2.479 0.323 - 491.9 1 2 0 0.0038 13 0 0 0 6.05E+06 7.35E+06 - - - 3.7555 1 230117_WJC_METTL3_WT_vs_EV_F04.21231.21231.2 5.75E-05 15/24 K.DAAIYLVTSLASK.A sp|P55060|XPO2_HUMAN 1 1350.7395 0.82 35210 21231 2 1350.742394 676.377 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.83 3887.5 - 1.25E+06 - - - 2.1559 - 2.928 0.518 - 757.9 1 2 0 0.0029 13 0 0 0 6.05E+06 7.35E+06 - - - 5.6233 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21232.21232.2 0.00118 13/22 R.GLFIIDPNGVIK[136.11].H sp|P30048|PRDX3_HUMAN 1 1292.7584 2.27 35211 21232 2 1292.761511 647.3865 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3887.6 - 1.23E+06 - - - 2.4266 - 2.253 0.317 - 432.3 1 2 0 0.0031 12 0 0 0 1.72E+07 7.58E+06 - - - 3.5186 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21234.21234.2 0.000193 13/20 R.LTGLLDLALEK.D sp|P04746|AMYP_HUMAN 1 1184.7016 -1 35213 21234 2 1184.704719 593.3581 Pancreatic alpha-amylase OS=Homo sapiens OX=9606 GN=AMY2A PE=1 SV=2 4.37 3887.9 - 506684 - - - 2.599 - 2.498 0.398 - 394.9 1 2 0 0.0031 11 0 0 0 0.00E+00 0.00E+00 - - - 4.4563 1 230117_WJC_METTL3_WT_vs_EV_F04.21235.21235.2 0.000191 15/26 R.YAIQLITAASLVC[160.03]R.K sp|Q9Y230|RUVB2_HUMAN 1 1577.8599 -1 35214 21235 2 1577.863309 789.9373 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 8.22 3888 - 390381 - - - 2.1295 - 3.06 0.563 - 854.6 1 2 0 0.0034 14 0 0 0 0.00E+00 0.00E+00 - - - 6.0049 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21237.21237.2 0.000327 30-Jul R.LFVGNLPADITEDEFK.R sp|P23246|SFPQ_HUMAN 1 1806.904 0.99 35216 21237 2 1806.904029 904.4593 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3888.3 - 367691 - - - 0.0266 - 1.887 0.431 - 36.1 1 2 0 0 16 0 0 0 2.24E+06 2.27E+06 - - - 3.7855 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.21239.21239.2 0.00314 30-Jul R.LFVGNLPADITEDEFK[136.11].R sp|P23246|SFPQ_HUMAN 1 1814.9182 -1 35218 21239 2 1814.915593 908.4664 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3888.5 - 300984 - - - -1.426 - 1.618 0.408 - 45 1 2 0 -0.0026 16 0 0 0 0.00E+00 0.00E+00 - - - 3.2367 1 230117_WJC_METTL3_WT_vs_EV_F04.21240.21240.2 0.00026 20-Dec K.TITAYFGDLIR[166.11].R sp|Q96RS0|TGS1_HUMAN 1 1278.6848 1.4 35219 21240 2 1278.690454 640.3497 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 5.5 3888.7 - 264180 - - - 4.4546 - 2.273 0.555 - 439 1 2 0 0.0057 11 0 0 0 3.34E+06 2.39E+06 - - - 5.3597 1 230117_WJC_METTL3_WT_vs_EV_F04.21242.21242.2 4.48E-06 15/26 K.LFSLELVDESGEIR[166.11].A sp|P27694|RFA1_HUMAN 1 1615.8333 0.11 35220 21242 2 1615.832357 808.9239 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4 3888.9 - 6.45E+06 - - - -0.5669 - 2.883 0.537 - 879.8 1 2 0 -0.0009 14 0 0 0 2.66E+06 2.42E+07 - - - 5.6641 1 230117_WJC_METTL3_WT_vs_EV_F04.21245.21245.2 1.67E-05 14/22 R.NFGASLLLPGLK[136.11].Q "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN,tr|D6RJC7|D6RJC7_HUMAN" 4 1236.7322 1.75 35223 21245 2 1236.735136 619.3734 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 8.75 3889.3 - 2.46E+06 - - - 2.4072 - 2.043 0.534 - 598.1 1 2 0 0.003 12 0 0 0 1.59E+07 9.09E+06 - - - 4.8639 1 230117_WJC_METTL3_WT_vs_EV_F04.21247.21247.2 0.00182 15/24 K.NVLIVEDIIDTGK.T sp|P00492|HPRT_HUMAN 1 1427.7872 -1 35225 21247 2 1427.791759 714.9009 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.03 3889.5 - 1.24E+06 - - - 3.2204 - 2.763 0.541 - 682.2 1 2 0 0.0046 13 0 0 0 0.00E+00 0.00E+00 - - - 5.6438 0.8948 230117_WJC_METTL3_WT_vs_EV_F04.21248.21248.2 0.019 24-Oct L.REVTYFSLWYYNK.Q "sp|Q16825|PTN21_HUMAN,tr|G3V3S6|G3V3S6_HUMAN" 2 1767.8621 78.64 35226 21248 2 1767.861035 884.9383 Tyrosine-protein phosphatase non-receptor type 21 OS=Homo sapiens OX=9606 GN=PTPN21 PE=1 SV=2 8.43 3889.6 - 1.12E+06 - - - -0.5781 - 1.774 0.305 - 173.8 1 1 0 -0.001 13 0 0 0 7.28E+06 9.26E+04 - - - 2.7646 1 230117_WJC_METTL3_WT_vs_EV_F04.21251.21251.2 1.14E-05 22-Sep S.ILTIEDGIFEVK.S "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1375.7599 -1 35229 21251 2 1375.76422 688.8872 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3890 - 405101 - - - 3.1524 - 2.031 0.519 - 238.2 1 1 0 0.0043 12 0 0 0 0.00E+00 0.00E+00 - - - 4.7372 1 230117_WJC_METTL3_WT_vs_EV_F04.21252.21252.2 1.41E-06 14/32 R.LWVGGLGPNTSLAALAR.E sp|Q8NDT2|RB15B_HUMAN 1 1694.9468 -1 35230 21252 2 1694.948565 848.4807 Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3 9.75 3890.2 - 374461 - - - 1.0472 - 2.957 0.55 - 443.5 1 2 0 0.0018 17 0 0 0 0.00E+00 0.00E+00 - - - 5.7682 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.21254.21254.2 0.00192 22-Nov K.SLPVSVPVWGFK[136.11].E sp|Q96B36|AKTS1_HUMAN 1 1322.7478 -1 35232 21254 2 1322.751834 662.3812 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 8.47 3890.4 - 330057 - - - 3.0429 - 1.757 0.286 - 345.7 1 2 0 0.004 12 0 0 0 0.00E+00 0.00E+00 - - - 2.6351 1 230117_WJC_METTL3_WT_vs_EV_F04.21255.21255.2 3.02E-07 Dec-32 R.LWVGGLGPNTSLAALAR[166.11].E sp|Q8NDT2|RB15B_HUMAN 1 1704.9551 -1 35233 21255 2 1704.956045 853.4848 Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3 9.75 3890.6 - 312070 - - - 0.5777 - 2.812 0.53 - 368.2 1 2 0 0.001 17 0 0 0 0.00E+00 0.00E+00 - - - 5.4972 0.9598 230117_WJC_METTL3_WT_vs_EV_F04.21256.21256.3 0.279 Dec-52 K.LFSLELVDESGEIR[166.11].A sp|P27694|RFA1_HUMAN 1 1615.8333 -1 35234 21256 3 1615.837171 539.6184 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4 3890.7 - 274361 - - - 2.4124 - 1.463 0.107 - 111.4 1 2 0 0.0039 14 0 0 0 0.00E+00 0.00E+00 - - - 0.743 1 230117_WJC_METTL3_WT_vs_EV_F04.21258.21258.2 7.31E-07 26-Nov Y.LLNPDGLFTDYYGR.S sp|O43819|SCO2_HUMAN 1 1642.7991 6.4 35236 21258 2 1642.800305 822.4068 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 4.21 3891 - 217596 - - - 0.7201 - 2.04 0.528 - 261.8 1 1 0 0.0012 14 0 0 0 2.15E+06 3.36E+05 - - - 4.7295 1 230117_WJC_METTL3_WT_vs_EV_F04.21259.21259.2 1.81E-13 23/34 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.81 35237 21259 2 1936.012256 969.0131 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3891.1 - 197164 - - - 0.3445 - 4.38 0.656 - 1519 1 2 0 0.0007 18 0 0 0 2.24E+07 2.75E+07 - - - 7.5174 1 230117_WJC_METTL3_WT_vs_EV_F04.21260.21260.2 2.89E-07 14/30 R.IGNVEISQVTIVGIIR[166.11].H "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 1720.0122 -1 35238 21260 2 1720.013345 861.0134 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 6 3891.2 - 190913 - - - 0.6424 - 2.803 0.544 - 590.1 1 2 0 0.0011 16 0 0 0 0.00E+00 0.00E+00 - - - 5.5926 1 230117_WJC_METTL3_WT_vs_EV_F04.21261.21261.2 2.88E-14 23/34 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.81 35239 21261 2 1926.003199 964.0089 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3891.4 - 164172 - - - -0.0623 - 4.51 0.685 - 1733 1 2 0 -0.0001 18 0 0 0 2.24E+07 2.75E+07 - - - 7.8037 1 230117_WJC_METTL3_WT_vs_EV_F04.21265.21265.2 7.17E-08 15/26 K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.77 35242 21265 2 1651.933389 826.9731 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3891.9 - 7.85E+06 - - - 1.0545 - 2.7 0.587 - 649.5 1 2 0 0.0017 14 0 0 0 6.25E+07 8.16E+07 - - - 5.8686 1 230117_WJC_METTL3_WT_vs_EV_F04.21266.21266.3 1.35E-09 25/68 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.83 35243 21266 3 1936.016101 646.3445 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3892 - 5.04E+06 - - - 2.3306 - 3.45 0.601 - 692.4 1 2 0 0.0045 18 0 0 0 1.19E+07 1.43E+07 - - - 8.323 1 230117_WJC_METTL3_WT_vs_EV_F04.21267.21267.2 2.57E-08 16/26 K.LYTLVTYVPVTTFK.N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1643.9174 0.77 35244 21267 2 1643.918903 822.966 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3892.1 - 4.94E+06 - - - 0.8857 - 2.759 0.583 - 819.6 1 2 0 0.0015 14 0 0 0 6.25E+07 8.16E+07 - - - 5.8933 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.21268.21268.3 8.08E-07 27/68 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.84 35245 21268 3 1926.009542 643.0084 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3892.2 - 3.64E+06 - - - 3.231 - 2.873 0.558 - 541.8 1 2 0 0.0062 18 0 0 0 1.20E+07 1.43E+07 - - - 7.3874 1 230117_WJC_METTL3_WT_vs_EV_F04.21272.21272.3 4.77E-08 21/52 K.LPLFPEPLHVFAPR.A "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|K7ENW7|K7ENW7_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 7 1631.9188 1.05 35249 21272 3 1631.922648 544.9802 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 6.75 3892.7 - 633543 - - - 2.3678 - 3.507 0.574 - 804.7 1 2 0 0.0039 14 0 0 0 9.50E+06 9.07E+06 - - - 8.273 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21274.21274.2 0.0293 20-Dec K.LLTQYILNLGK.Y sp|O00203|AP3B1_HUMAN 1 1274.7598 -1 35251 21274 2 1274.764237 638.3872 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 8.59 3893 - 552922 - - - 3.4618 - 2.169 0.413 - 480.8 1 2 0 0.0044 11 0 0 0 0.00E+00 0.00E+00 - - - 4.1846 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21276.21276.3 0.00123 15/52 K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 1.04 35253 21276 3 1651.935428 551.6512 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3893.3 - 468439 - - - 2.2888 - 2.087 0.278 - 176.6 1 2 0 0.0038 14 0 0 0 8.29E+06 7.95E+06 - - - 3.5936 0.9844 230117_WJC_METTL3_WT_vs_EV_F04.21277.21277.2 0.336 24-Jun K.NPLPVTLTNVVFR.L "sp|P22735|TGM1_HUMAN,tr|H0YMQ8|H0YMQ8_HUMAN" 2 1468.8402 -1 35254 21277 2 1468.84651 735.4274 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 9.75 3893.4 - 458903 - - - 4.2966 - 1.53 0.165 - 90.9 2 2 0 0.0063 13 0 0 0 0.00E+00 0.00E+00 - - - 1.2147 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21286.21286.2 0.000179 22-Oct R.LFQVEYAIEAIK.L sp|P28066|PSA5_HUMAN 1 1422.7759 2.38 35262 21286 2 1422.777527 712.3952 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 4.53 3894.5 - 4.14E+06 - - - 1.166 - 2.176 0.436 - 323.3 1 2 0 0.0017 12 0 0 0 3.67E+07 1.55E+07 - - - 4.3065 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21288.21288.2 0.00335 20-Dec R.EALDVLGAVLK.A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1126.6598 1.34 35264 21288 2 1126.661006 564.3372 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3894.7 - 1.21E+06 - - - 1.0926 - 2.177 0.337 - 488.8 1 2 0 0.0012 11 0 0 0 1.57E+08 1.17E+08 - - - 3.6342 1 230117_WJC_METTL3_WT_vs_EV_F04.21289.21289.2 0.000134 20-Oct R.EALDVLGAVLK[136.11].A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1134.674 1.34 35265 21289 2 1134.674612 568.3443 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3894.8 - 926186 - - - 0.5614 - 2.189 0.478 - 272.7 1 2 0 0.0006 11 0 0 0 1.57E+08 1.17E+08 - - - 4.6907 1 230117_WJC_METTL3_WT_vs_EV_F04.21292.21292.2 0.000503 14/24 R.VLGATLLPDLIQK.V "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN,tr|H0YDG0|H0YDG0_HUMAN" 5 1379.8388 1.83 35268 21292 2 1379.84174 690.9267 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.81 3895.2 - 659377 - - - 2.1292 - 2.632 0.47 - 534.6 1 2 0 0.0029 13 0 0 0 1.62E+07 8.89E+06 - - - 4.9952 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21294.21294.2 0.0736 20-Nov R.NLIIEAVTNLR[166.11].L "sp|Q12789|TF3C1_HUMAN,tr|H3BU37|H3BU37_HUMAN" 2 1264.7379 0.3 35270 21294 2 1264.738747 633.3762 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 6 3895.4 - 550817 - - - 0.7045 - 2.1 0.257 - 543.3 1 2 0 0.0009 11 0 0 0 1.17E+06 3.94E+06 - - - 2.946 1 230117_WJC_METTL3_WT_vs_EV_F04.21295.21295.2 1.40E-07 18-Oct R.VYNALVAFIR.A sp|Q9BW92|SYTM_HUMAN 1 1164.6655 0.12 35271 21295 2 1164.665291 583.34 "Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1" 8.72 3895.6 - 535735 - - - -0.2044 - 2.329 0.564 - 293.4 1 2 0 -0.0002 10 0 0 0 1.28E+06 1.04E+07 - - - 5.5665 1 230117_WJC_METTL3_WT_vs_EV_F04.21298.21298.2 7.94E-07 20-Dec K.TLC[160.03]PLC[160.03]FSILK[136.11].G "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1358.7182 1.35 35274 21298 2 1358.715229 680.3664 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 7.74 3896 - 455365 - - - -2.1616 - 2.112 0.52 - 392.8 1 2 0 -0.0029 11 0 0 0 4.23E+06 3.14E+06 - - - 4.9033 1 230117_WJC_METTL3_WT_vs_EV_F04.21301.21301.2 3.63E-06 13/24 R.VLGATLLPDLIQK[136.11].V "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN,tr|H0YDG0|H0YDG0_HUMAN" 5 1387.853 1.83 35277 21301 2 1387.855512 694.9338 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.81 3896.4 - 386679 - - - 1.8085 - 2.619 0.498 - 479.6 1 2 0 0.0025 13 0 0 0 1.62E+07 8.89E+06 - - - 5.1895 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.21303.21303.2 0.345 14-Jul K.QFLIDWVR.K "sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 2 1075.5815 1 35279 21303 2 1075.582818 538.798 ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2 5.84 3896.6 - 360441 - - - 1.2579 - 1.49 0.223 - 149.9 1 2 0 0.0014 8 0 0 0 1.94E+06 1.95E+06 - - - 1.8903 1 230117_WJC_METTL3_WT_vs_EV_F04.21305.21305.2 1.01E-05 14/28 R.TIAIIAEGIPEALTR.K sp|P53396|ACLY_HUMAN 1 1566.8981 -1 35280 21305 2 1566.898806 784.4563 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.53 3897 - 234216 - - - 0.4455 - 2.793 0.587 - 675.8 1 2 0 0.0007 15 0 0 0 0.00E+00 0.00E+00 - - - 5.9016 1 230117_WJC_METTL3_WT_vs_EV_F04.21306.21306.2 2.68E-05 22-Oct R.IAAQDYIIGVFR[166.11].K "sp|Q96RR1|PEO1_HUMAN,tr|A0A2R8Y4V4|A0A2R8Y4V4_HUMAN,tr|A0A2R8Y746|A0A2R8Y746_HUMAN" 3 1374.7535 1.22 35281 21306 2 1374.760502 688.384 Twinkle mtDNA helicase OS=Homo sapiens OX=9606 GN=TWNK PE=1 SV=1 5.84 3897 - 352869 - - - 5.0889 - 2.249 0.482 - 286.5 1 2 0 0.007 12 0 0 0 5.14E+06 4.22E+06 - - - 4.7314 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21308.21308.2 0.000181 18-Aug K.C[160.03]MQLTDFILK[136.11].F "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1275.6447 0.71 35283 21308 2 1275.645988 638.8296 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.83 3897.1 - 2.56E+06 - - - 1.0363 - 1.742 0.457 - 165.8 1 2 0 0.0013 10 0 0 0 3.60E+07 5.11E+07 - - - 3.9653 1 230117_WJC_METTL3_WT_vs_EV_F04.21309.21309.2 1.37E-05 18-Nov K.C[160.03]MQLTDFILK.F "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1267.6305 0.71 35284 21309 2 1267.631931 634.8225 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.83 3897.2 - 1.73E+06 - - - 1.1557 - 2.248 0.499 - 398.1 1 2 0 0.0015 10 0 0 0 3.60E+07 5.11E+07 - - - 4.9872 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21310.21310.2 0.00238 18-Nov K.LLEPVLLLGK[136.11].E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1101.7253 1.75 35285 21310 2 1101.724563 551.8699 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3897.2 - 1.16E+06 - - - -0.6535 - 2.098 0.372 - 354.8 1 2 0 -0.0007 10 0 0 0 1.13E+09 6.45E+08 - - - 3.8567 1 230117_WJC_METTL3_WT_vs_EV_F04.21311.21311.2 5.16E-10 26-Nov R.VIVSDVQESFIWVR[166.11].Y sp|Q15393|SF3B3_HUMAN 1 1685.9016 1.24 35286 21311 2 1685.902826 843.9581 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3897.3 - 903636 - - - 0.7112 - 2.589 0.656 - 296.5 1 2 0 0.0012 14 0 0 0 2.02E+07 1.63E+07 - - - 6.273 1 230117_WJC_METTL3_WT_vs_EV_F04.21313.21313.2 2.71E-07 24-Dec K.YVFLDPLAGAVTK[136.11].T "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|A8MWX3|WASH4_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 6 1400.7795 2.28 35288 21313 2 1400.778848 701.397 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 5.83 3897.4 - 458171 - - - -0.4676 - 2.397 0.618 - 376.1 1 2 0 -0.0007 13 0 0 0 2.87E+07 1.26E+07 - - - 5.849 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.21316.21316.2 0.0929 14-Jul R.IPFAFWAR.Y "sp|Q96JG8|MAGD4_HUMAN,tr|A0A804HKI1|A0A804HKI1_HUMAN" 2 1006.5389 0.25 35291 21316 2 1006.537649 504.2767 Melanoma-associated antigen D4 OS=Homo sapiens OX=9606 GN=MAGED4 PE=1 SV=3 9.75 3897.8 - 292920 - - - -1.2151 - 1.32 0.361 - 149.4 1 2 0 -0.0012 8 0 0 0 1.20E+06 4.71E+06 - - - 2.5443 0.868 230117_WJC_METTL3_WT_vs_EV_F04.21318.21318.2 3.29 20-May K.ELTPLQAMMLR[166.11].M sp|Q9Y2W2|WBP11_HUMAN 1 1311.6918 0.43 35293 21318 2 1311.690638 656.8532 WW domain-binding protein 11 OS=Homo sapiens OX=9606 GN=WBP11 PE=1 SV=1 6.1 3897.9 - 209307 - - - -0.9118 - 1.092 0.036 - 81.7 3 2 0 -0.0012 11 0 0 0 6.41E+05 1.50E+06 - - - -0.6685 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.21323.21323.2 0.0131 18-Aug K.LLEPVLLLGK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1093.7111 1.75 35296 21323 2 1093.713213 547.8628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3898.5 - 1.12E+07 - - - 1.9475 - 1.597 0.191 - 161 1 2 0 0.0021 10 0 0 0 1.13E+09 6.45E+08 - - - 1.7577 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21324.21324.2 0.00211 20-Nov K.IALLNVELELK.A sp|Q99832|TCPH_HUMAN 1 1253.7595 11.47 35297 21324 2 1253.761225 627.887 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.53 3898.5 - 1.09E+07 - - - 1.3846 - 2.508 0.401 - 440 1 2 0 0.0017 11 0 0 0 8.37E+07 7.30E+06 - - - 4.4897 1 230117_WJC_METTL3_WT_vs_EV_F04.21326.21326.2 2.86E-06 13/24 R.LDPETLESLGLIK[136.11].Q "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 1434.8061 1.86 35299 21326 2 1434.806192 718.4103 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 4.14 3898.7 - 1.77E+06 - - - 0.0558 - 2.45 0.569 - 614.4 1 2 0 0.0001 13 0 0 0 3.00E+07 1.61E+07 - - - 5.5434 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21329.21329.2 0.00312 20-Oct K.IALLNVELELK[136.11].A sp|Q99832|TCPH_HUMAN 1 1261.7737 11.47 35302 21329 2 1261.773998 631.8941 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.53 3898.9 - 1.08E+06 - - - 0.2449 - 2.382 0.427 - 332.4 1 2 0 0.0003 11 0 0 0 8.37E+07 7.30E+06 - - - 4.5427 1 230117_WJC_METTL3_WT_vs_EV_F04.21330.21330.2 1.76E-07 20-Dec R.FVASYLEYAFR.K sp|Q96GM8|TOE1_HUMAN 1 1364.6765 1.68 35303 21330 2 1364.676368 683.3455 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 6 3899 - 682216 - - - -0.0879 - 2.348 0.564 - 498.5 1 2 0 -0.0001 11 0 0 0 4.89E+06 2.91E+06 - - - 5.5158 1 230117_WJC_METTL3_WT_vs_EV_F04.21332.21332.2 2.24E-07 24-Sep K.FDFPVSYLPGPVK.A "sp|Q9NXE4|NSMA3_HUMAN,tr|A0A7P0T8J0|A0A7P0T8J0_HUMAN,tr|A0A7P0Z453|A0A7P0Z453_HUMAN,tr|C9J647|C9J647_HUMAN,tr|A0A7P0TAZ0|A0A7P0TAZ0_HUMAN,tr|A0A7P0T9J6|A0A7P0T9J6_HUMAN,tr|A0A7P0TB24|A0A7P0TB24_HUMAN" 7 1464.7653 2.6 35305 21332 2 1464.763423 733.3899 Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3 5.83 3899.3 - 648812 - - - -1.2835 - 1.935 0.555 - 200.6 1 2 0 -0.0019 13 0 0 0 4.48E+06 1.73E+06 - - - 4.8338 1 230117_WJC_METTL3_WT_vs_EV_F04.21334.21334.2 1.30E-08 17/36 R.LFVSDGVPGC[160.03]LPVLAAAGR.A "sp|P56192|SYMC_HUMAN,tr|F8W0S4|F8W0S4_HUMAN,tr|F8W0M7|F8W0M7_HUMAN,tr|F8VPL7|F8VPL7_HUMAN,tr|F5H2V6|F5H2V6_HUMAN,tr|F8VS26|F8VS26_HUMAN,tr|F8VZZ9|F8VZZ9_HUMAN" 7 1898.0084 1.64 35307 21334 2 1898.015121 950.0115 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 5.83 3899.5 - 480379 - - - 3.539 - 3.082 0.622 - 359.7 1 2 0 0.0067 19 0 0 0 5.10E+06 3.11E+06 - - - 6.4003 0.9711 230117_WJC_METTL3_WT_vs_EV_F04.21339.21339.2 0.322 14-Jun R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 1.12 35312 21339 2 1000.558827 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3900.1 - 249783 - - - -0.5057 - 1.409 0.036 - 77 2 2 0 -0.0005 8 0 0 0 1.14E+06 1.02E+06 - - - 0.2064 0.9955 230117_WJC_METTL3_WT_vs_EV_F04.21345.21345.2 0.00347 18-Aug K.LLLNLVDC[160.03]IR.S "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1227.7009 2.28 35317 21345 2 1227.696949 614.8577 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 5.83 3900.9 - 0 - - - -3.2418 - 2.028 0.345 - 207.3 1 2 0 -0.004 10 0 0 0 4.20E+06 1.85E+06 - - - 3.5615 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21346.21346.2 0.00242 16-Nov R.DIDAFWLQR.Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1162.5771 1.59 35318 21346 2 1162.579067 582.2958 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3901.1 - 439834 - - - 1.685 - 2.017 0.467 - 408.2 1 2 0 0.002 9 0 0 0 2.54E+07 1.60E+07 - - - 4.5194 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21347.21347.2 0.00263 16-Oct R.DIDAFWLQR[166.11].Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1172.5854 1.59 35319 21347 2 1172.587004 587.3 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3901.1 - 430802 - - - 1.3867 - 1.987 0.392 - 373.5 1 2 0 0.0016 9 0 0 0 2.54E+07 1.60E+07 - - - 3.9222 1 230117_WJC_METTL3_WT_vs_EV_F04.21352.21352.2 0.000191 18-Nov K.QEVPIIIVFR.A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1212.723 1.19 35322 21352 2 1212.723456 607.3688 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3901.8 - 490034 - - - 0.3397 - 2.287 0.539 - 443.7 1 2 0 0.0004 10 0 0 0 2.83E+07 2.39E+07 - - - 5.331 1 230117_WJC_METTL3_WT_vs_EV_F04.21353.21353.2 0.000393 18-Nov K.QEVPIIIVFR[166.11].A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1222.7313 1.19 35323 21353 2 1222.73231 612.3729 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3901.9 - 127099 - - - 0.8146 - 2.146 0.505 - 509.1 1 2 0 0.001 10 0 0 0 2.83E+07 2.39E+07 - - - 4.9021 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21355.21355.2 0.000221 14-Sep K.NFAFLEFR[166.11].S "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1052.5319 1.36 35325 21355 2 1052.53301 527.2732 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3902.1 - 435589 - - - 1.0679 - 1.743 0.425 - 426.6 1 2 0 0.0011 8 0 0 0 2.07E+07 1.52E+07 - - - 3.8554 1 230117_WJC_METTL3_WT_vs_EV_F04.21356.21356.2 0.00026 22-Sep R.LGAPGFAWEPFR.G "sp|Q9HCM7|FBSL_HUMAN,tr|A0A3B3IRR3|A0A3B3IRR3_HUMAN,tr|A0A7P0Z485|A0A7P0Z485_HUMAN" 3 1346.6772 2.84 35326 21356 2 1346.677584 674.3459 Fibrosin-1-like protein OS=Homo sapiens OX=9606 GN=FBRSL1 PE=1 SV=4 6 3902.2 - 215899 - - - 0.3171 - 2.268 0.515 - 310.6 1 2 0 0.0004 12 0 0 0 3.62E+06 1.27E+06 - - - 4.9993 0.8757 230117_WJC_METTL3_WT_vs_EV_F04.21357.21357.2 0.634 14-Jul N.GVSQLIQR[166.11].E sp|P48201|AT5G3_HUMAN 1 909.5271 0.9 35327 21357 2 909.52692 455.7708 "ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1" 9.75 3902.4 - 204326 - - - -0.2364 - 1.591 0.255 - 209.5 1 1 0 -0.0002 8 0 0 0 2.04E+08 2.27E+08 - - - 2.3249 0.9494 230117_WJC_METTL3_WT_vs_EV_F04.21360.21360.2 1.28E-05 15/24 K.ALEVAEYLTPVLK.E "sp|Q9NT62|ATG3_HUMAN,tr|F8WDI0|F8WDI0_HUMAN" 2 1444.8177 3.27 35330 21360 2 1445.825778 723.4161 Ubiquitin-like-conjugating enzyme ATG3 OS=Homo sapiens OX=9606 GN=ATG3 PE=1 SV=1 4.53 3902.7 - 0 - - - 697.697 - 2.631 0.422 - 774.4 1 2 0 1.008 13 0 0 0 4.25E+06 1.30E+06 - - - 4.3241 1 230117_WJC_METTL3_WT_vs_EV_F04.21361.21361.2 1.85E-10 17/32 R.EIISEMGELGVLGPTIK[136.11].G "sp|Q92947|GCDH_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKT3|K7EKT3_HUMAN" 3 1792.9736 -1 35331 21361 2 1792.975965 897.4941 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.25 3902.9 - 0 - - - 1.3257 - 3.383 0.631 - 945.2 1 2 0 0.0024 17 0 0 0 0.00E+00 0.00E+00 - - - 6.6972 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.21363.21363.3 0.000181 16/68 K.VLNEAVGALMYHTITLTR.E "sp|Q13363|CTBP1_HUMAN,tr|E7ESU7|E7ESU7_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|E7EPF8|E7EPF8_HUMAN,tr|E9PGB1|E9PGB1_HUMAN" 5 2001.0717 -1 35333 21363 3 2001.066769 668.0312 C-terminal-binding protein 1 OS=Homo sapiens OX=9606 GN=CTBP1 PE=1 SV=2 6.72 3903.1 - 154264 - - - -2.4802 - 2.431 0.394 - 194 1 2 0 -0.005 18 0 0 0 0.00E+00 0.00E+00 - - - 5.1433 1 230117_WJC_METTL3_WT_vs_EV_F04.21364.21364.2 5.57E-06 14/26 Y.VAIQAVLSLYASGR[166.11].T "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 19 1456.8277 1.56 35334 21364 2 1456.828265 729.4211 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 8.72 3903.3 - 0 - - - 0.3645 - 3.011 0.4 - 867.9 1 1 0 0.0005 14 0 0 0 2.38E+06 1.53E+06 - - - 4.7613 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21368.21368.2 0.00422 18-Sep K.LFEISDIVIK.D sp|Q9NSD9|SYFB_HUMAN 1 1175.6802 1.66 35336 21368 2 1175.681576 588.8474 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 4.37 3903.7 - 2.04E+06 - - - 1.1908 - 1.884 0.375 - 244.8 1 2 0 0.0014 10 0 0 0 1.52E+07 9.16E+06 - - - 3.5783 1 230117_WJC_METTL3_WT_vs_EV_F04.21372.21372.2 0.00626 16-Oct R.IPILFFANK.M "sp|Q9H0F7|ARL6_HUMAN,tr|A0A0J9YXT0|A0A0J9YXT0_HUMAN,tr|H7C5H6|H7C5H6_HUMAN" 3 1061.6274 2.86 35340 21372 2 1061.627809 531.821 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3904 - 1.41E+06 - - - 0.4295 - 2.351 0.429 - 401 1 2 0 0.0005 9 0 0 0 4.90E+06 1.71E+06 - - - 4.6826 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.21373.21373.2 0.00156 14-Aug K.SFDLLILK[136.11].E "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 955.5834 0.87 35341 21373 2 955.583028 478.799 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 5.55 3904.1 - 1.34E+06 - - - -0.3569 - 1.698 0.462 - 187.1 1 2 0 -0.0003 8 0 0 0 6.61E+06 7.57E+06 - - - 4.05 1 230117_WJC_METTL3_WT_vs_EV_F04.21374.21374.2 2.53E-08 14/24 K.TVQTAVFLYSLYK.E "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 1531.8286 0.88 35342 21374 2 1531.829528 766.9216 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.17 3904.2 - 1.30E+06 - - - 0.5849 - 2.729 0.608 - 523.3 1 2 0 0.0009 13 0 0 0 7.91E+06 9.00E+06 - - - 6.108 1 230117_WJC_METTL3_WT_vs_EV_F04.21375.21375.2 2.76E-10 19/32 R.VLALSVETDYTFPLAEK[136.11].V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN" 5 1903.007 1.28 35343 21375 2 1903.007456 952.5108 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 4.14 3904.3 - 1.05E+06 - - - 0.2417 - 4.539 0.669 - 998.8 1 2 0 0.0005 17 0 0 0 4.99E+06 3.89E+06 - - - 7.7011 0.9983 230117_WJC_METTL3_WT_vs_EV_F04.21376.21376.2 0.126 14-Aug K.SFDLLILK.E "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 947.5692 0.87 35344 21376 2 947.569268 474.7919 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 5.55 3904.4 - 959845 - - - 0.1045 - 1.31 0.317 - 197.3 1 2 0 0.0001 8 0 0 0 6.61E+06 7.57E+06 - - - 2.1967 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21378.21378.2 0.00275 18-Jul K.LFEISDIVIK[136.11].D sp|Q9NSD9|SYFB_HUMAN 1 1183.6944 3.25 35346 21378 2 1183.6956 592.8545 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 4.37 3904.7 - 749570 - - - 1.0341 - 1.763 0.358 - 98.3 1 2 0 0.0012 10 0 0 0 1.38E+07 4.25E+06 - - - 3.2675 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21381.21381.2 0.000531 22-Oct R.EVAAGYLVPLLR.S sp|Q13395|TARB1_HUMAN 1 1299.7551 2.14 35349 21381 2 1299.75789 650.8848 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6.1 3905.1 - 421155 - - - 2.1673 - 2.158 0.461 - 293.1 1 2 0 0.0028 12 0 0 0 4.56E+06 2.13E+06 - - - 4.4689 1 230117_WJC_METTL3_WT_vs_EV_F04.21382.21382.2 6.54E-06 14/24 K.VSASPLLYTLIEK[136.11].T "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1440.8319 2.44 35350 21382 2 1440.836255 721.4232 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 5.97 3905.2 - 417532 - - - 2.9997 - 2.77 0.511 - 617.1 1 2 0 0.0043 13 0 0 0 2.76E+07 1.13E+07 - - - 5.4288 1 230117_WJC_METTL3_WT_vs_EV_F04.21386.21386.2 2.88E-08 15/32 R.EIISEMGELGVLGPTIK.G "sp|Q92947|GCDH_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKT3|K7EKT3_HUMAN" 3 1784.9594 1.22 35354 21386 2 1784.963747 893.487 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.25 3905.7 - 312487 - - - 2.4421 - 3.204 0.617 - 664 1 2 0 0.0044 17 0 0 0 2.80E+06 2.29E+06 - - - 6.4595 1 230117_WJC_METTL3_WT_vs_EV_F04.21388.21388.2 1.29E-05 22-Oct R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 35355 21388 2 1603.764011 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3906 - 1.83E+07 - - - 0.0443 - 1.934 0.58 - 315.1 1 2 0 0.0001 12 0 0 0 5.80E+08 0.00E+00 - - - 5.0604 1 230117_WJC_METTL3_WT_vs_EV_F04.21389.21389.3 7.53E-06 Dec-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 35356 21389 3 1603.764771 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3906.2 - 310005 - - - 0.5182 - 2.238 0.551 - 188 1 2 0 0.0008 12 0 0 0 1.64E+07 0.00E+00 - - - 6.9158 1 230117_WJC_METTL3_WT_vs_EV_F04.21391.21391.2 9.11E-08 15/24 K.VFSATLGLVDIVK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1368.8108 1.11 35358 21391 2 1368.812927 685.4127 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3906.4 - 1.57E+06 - - - 1.5517 - 2.678 0.578 - 609.6 1 2 0 0.0021 13 0 0 0 2.75E+08 2.48E+08 - - - 5.8377 1 230117_WJC_METTL3_WT_vs_EV_F04.21392.21392.2 2.60E-07 17/24 K.VFSATLGLVDIVK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1360.7966 1.11 35359 21392 2 1360.799186 681.4056 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3906.5 - 1.39E+06 - - - 1.8982 - 2.837 0.591 - 838.7 1 2 0 0.0026 13 0 0 0 2.75E+08 2.48E+08 - - - 6.0816 1 230117_WJC_METTL3_WT_vs_EV_F04.21394.21394.2 1.56E-05 22-Dec K.VVYTSLQWASLQ.- "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN" 2 1393.7242 - 35361 21394 2 1393.721972 697.8694 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 5.49 3906.7 - 984380 - - - -1.5742 - 2.387 0.534 - 321.3 1 2 0 -0.0022 12 0 0 0 - - - - - 5.2737 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.21395.21395.3 0.000535 13/48 R.LLGNTFVALSDLR.C "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1417.7929 3.6 35362 21395 3 1417.795862 473.6049 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.84 3906.8 - 954730 - - - 2.0786 - 2.308 0.407 - 247.8 1 2 0 0.0029 13 0 0 0 5.77E+06 1.61E+06 - - - 5.3445 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.21398.21398.2 0.00209 24-Sep K.LLLDTFEYQGLVK[136.11].H "sp|Q7Z7K6|CENPV_HUMAN,tr|A0A0M3HER2|A0A0M3HER2_HUMAN" 2 1545.8534 1.59 35365 21398 2 1545.853434 773.934 Centromere protein V OS=Homo sapiens OX=9606 GN=CENPV PE=1 SV=1 4.37 3907.2 - 685981 - - - 0.0246 - 1.624 0.388 - 111.9 1 2 0 0 13 0 0 0 7.01E+06 4.40E+06 - - - 3.1512 1 230117_WJC_METTL3_WT_vs_EV_F04.21399.21399.2 1.61E-06 28-Nov K.IVFVPGC[160.03]SIPLTIVK.S sp|P54136|SYRC_HUMAN 1 1641.9528 1.5 35366 21399 2 1641.95639 821.9837 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3907.4 - 659871 - - - 2.1943 - 2.151 0.57 - 226.3 1 2 0 0.0036 15 0 0 0 7.54E+07 5.03E+07 - - - 5.133 0.9884 230117_WJC_METTL3_WT_vs_EV_F04.21401.21401.2 3.71 16-Aug R.LLPDFLLER[166.11].R "sp|Q12894|IFRD2_HUMAN,tr|H7C444|H7C444_HUMAN,tr|A0A0R4J2F6|A0A0R4J2F6_HUMAN" 3 1124.6469 0.35 35368 21401 2 1124.650503 563.3307 Interferon-related developmental regulator 2 OS=Homo sapiens OX=9606 GN=IFRD2 PE=1 SV=3 4.37 3907.6 - 597573 - - - 3.1894 - 1.675 0.076 - 106.2 3 2 0 0.0036 9 0 0 0 5.82E+06 1.66E+07 - - - 0.8804 1 230117_WJC_METTL3_WT_vs_EV_F04.21402.21402.2 0.000647 16/24 K.LDNLLLDTEGFVK.L sp|Q16513|PKN2_HUMAN 1 1475.7872 3.97 35369 21402 2 1475.792604 738.9009 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.03 3907.8 - 554656 - - - 3.6882 - 2.728 0.448 - 570.6 1 2 0 0.0054 13 0 0 0 8.00E+06 2.02E+06 - - - 4.9239 1 230117_WJC_METTL3_WT_vs_EV_F04.21403.21403.2 3.98E-06 28-Dec K.IVFVPGC[160.03]SIPLTIVK[136.11].S sp|P54136|SYRC_HUMAN 1 1649.967 1.5 35370 21403 2 1649.967693 825.9908 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3907.9 - 524136 - - - 0.4279 - 2.356 0.53 - 331.1 1 2 0 0.0007 15 0 0 0 7.54E+07 5.03E+07 - - - 5.0622 1 230117_WJC_METTL3_WT_vs_EV_F04.21406.21406.2 0.00135 15/22 K.IILDLISESPIK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1347.8105 1.11 35373 21406 2 1347.811308 674.9125 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3908.3 - 405872 - - - 0.6225 - 2.802 0.534 - 668.8 1 2 0 0.0008 12 0 0 0 5.14E+08 4.64E+08 - - - 5.6958 1 230117_WJC_METTL3_WT_vs_EV_F04.21411.21411.2 0.0009 14/22 K.IILDLISESPIK.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1339.7963 1.11 35377 21411 2 1339.797649 670.9054 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3908.7 - 2.60E+07 - - - 1.03 - 2.835 0.539 - 616.3 1 2 0 0.0014 12 0 0 0 5.14E+08 4.64E+08 - - - 5.7634 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.21414.21414.2 0.00306 16-Jul R.FWYFVSQLK[136.11].K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1224.6423 0.71 35380 21414 2 1224.642572 613.3284 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3908.8 - 1.24E+07 - - - 0.2376 - 1.356 0.352 - 171.9 1 2 0 0.0003 9 0 0 0 6.42E+07 9.02E+07 - - - 2.5218 1 230117_WJC_METTL3_WT_vs_EV_F04.21416.21416.2 1.35E-10 26-Dec K.FGGDFLVYPGDPLR.F "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN" 4 1551.7722 53.82 35382 21416 2 1551.772328 776.8934 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.21 3908.9 - 8.20E+06 - - - 0.096 - 2.393 0.661 - 472.7 1 2 0 0.0001 14 0 0 0 3.03E+07 5.63E+05 - - - 6.1127 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.21417.21417.2 0.00342 16-Aug R.FWYFVSQLK.K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1216.6281 0.71 35383 21417 2 1216.631399 609.3213 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3909 - 6.11E+06 - - - 2.7272 - 1.699 0.411 - 233 1 2 0 0.0033 9 0 0 0 6.42E+07 9.02E+07 - - - 3.609 1 230117_WJC_METTL3_WT_vs_EV_F04.21419.21419.2 6.91E-06 24-Dec R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 1.51 35385 21419 2 1448.79126 725.4024 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3909.1 - 3.24E+06 - - - 0.6723 - 2.713 0.507 - 496.2 1 2 0 0.001 13 0 0 0 2.19E+08 1.45E+08 - - - 5.3469 1 230117_WJC_METTL3_WT_vs_EV_F04.21421.21421.2 0.0398 14/26 K.VLLLSSPGLEELYR[166.11].C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1597.8955 0.99 35387 21421 2 1597.893906 799.955 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3909.2 - 2.86E+06 - - - -0.9844 - 2.717 0.446 - 618.2 1 2 0 -0.0016 14 0 0 0 3.85E+07 3.91E+07 - - - 4.8429 0.9293 230117_WJC_METTL3_WT_vs_EV_F04.21422.21422.2 0.667 16-Jun K.TVFDNFFIK.K sp|Q9H040|SPRTN_HUMAN 1 1129.5808 4.22 35388 21422 2 1129.578624 565.7977 DNA-dependent metalloprotease SPRTN OS=Homo sapiens OX=9606 GN=SPRTN PE=1 SV=2 5.5 3909.3 - 2.66E+06 - - - -1.9237 - 1.041 0.139 - 71.9 1 2 0 -0.0022 9 0 0 0 4.33E+06 1.03E+06 - - - 0.1832 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.21424.21424.2 0.0265 16-Aug K.VDILEMLQK.A "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1087.5947 1.3 35390 21424 2 1087.593688 544.8046 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.37 3909.4 - 2.29E+06 - - - -0.9599 - 1.639 0.373 - 160.5 1 2 0 -0.001 9 0 0 0 5.56E+06 4.28E+06 - - - 3.2251 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21426.21426.2 0.000418 14-Jul R.FDMIFIVK.D "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1011.5463 1.51 35392 21426 2 1011.546651 506.7804 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 5.84 3909.6 - 1.98E+06 - - - 0.3223 - 1.697 0.418 - 116.7 1 2 0 0.0003 8 0 0 0 5.38E+06 3.56E+06 - - - 3.7233 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.21438.21438.2 0.116 16-Jul R.AITILEMIK.R sp|Q52LR7|EPC2_HUMAN 1 1030.6097 -1 35403 21438 2 1030.611002 516.3121 Enhancer of polycomb homolog 2 OS=Homo sapiens OX=9606 GN=EPC2 PE=1 SV=2 6.05 3910.8 - 0 - - - 1.308 - 1.361 0.232 - 101.8 1 2 0 0.0013 9 0 0 0 0.00E+00 0.00E+00 - - - 1.6458 1 230117_WJC_METTL3_WT_vs_EV_F04.21442.21442.2 4.83E-06 13/24 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.52 35405 21442 2 1438.780102 720.3983 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3911.3 - 1.89E+07 - - - -1.3303 - 2.854 0.526 - 629.4 1 2 0 -0.0019 13 0 0 0 2.19E+08 1.45E+08 - - - 5.617 0.9963 230117_WJC_METTL3_WT_vs_EV_F04.21443.21443.2 0.00124 14/26 K.VLLLSSPGLEELYR.C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1587.8872 0.99 35406 21443 2 1587.881562 794.9509 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3911.3 - 4.04E+06 - - - -3.5563 - 2.532 0.41 - 602.7 1 2 0 -0.0056 14 0 0 0 3.85E+07 3.91E+07 - - - 4.3988 1 230117_WJC_METTL3_WT_vs_EV_F04.21445.21445.2 0.000134 13/16 R.IDLAVLLGK.T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 940.5957 2.03 35408 21445 2 940.595186 471.3051 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3911.6 - 2.43E+06 - - - -0.5656 - 2.524 0.503 - 459 1 2 0 -0.0005 9 0 0 0 3.22E+08 1.58E+08 - - - 5.4345 1 230117_WJC_METTL3_WT_vs_EV_F04.21447.21447.2 3.95E-06 22-Dec R.YFPTQALNFAFK[136.11].D "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 1453.7485 1.18 35410 21447 2 1453.742615 727.8815 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.59 3911.9 - 2.07E+06 - - - -4.0736 - 2.116 0.528 - 450.2 1 2 0 -0.0059 12 0 0 0 1.50E+08 1.27E+08 - - - 4.9111 1 230117_WJC_METTL3_WT_vs_EV_F04.21449.21449.2 0.00356 13/16 R.IDLAVLLGK[136.11].T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 948.6099 2.03 35412 21449 2 948.608981 475.3122 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3912.1 - 1.51E+06 - - - -0.9878 - 2.31 0.481 - 426.9 1 2 0 -0.0009 9 0 0 0 3.22E+08 1.58E+08 - - - 5.0156 1 230117_WJC_METTL3_WT_vs_EV_F04.21450.21450.2 8.64E-05 13/20 K.LPDVYGVFQFK[136.11].V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1319.7005 1.36 35413 21450 2 1319.700181 660.8575 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.83 3912.2 - 1.24E+06 - - - -0.2599 - 2.397 0.544 - 629.3 1 2 0 -0.0003 11 0 0 0 2.49E+07 1.83E+07 - - - 5.4238 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.21452.21452.3 1.43E-06 16/48 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.1 35415 21452 3 1438.781452 480.6013 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3912.5 - 896423 - - - -0.392 - 2.882 0.484 - 413.8 1 2 0 -0.0006 13 0 0 0 7.25E+06 6.57E+06 - - - 6.8058 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.21455.21455.3 0.000286 14/48 R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 1.1 35418 21455 3 1448.790159 483.9374 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3912.9 - 635929 - - - -0.0877 - 2.538 0.397 - 336.7 1 2 0 -0.0001 13 0 0 0 7.25E+06 6.57E+06 - - - 5.4914 0.9763 230117_WJC_METTL3_WT_vs_EV_F04.21457.21457.2 1.14 24-Aug K.NASILLEELDLEK.L "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1485.7926 -1 35420 21457 2 1485.791454 743.9036 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4 3913.2 - 587552 - - - -0.7982 - 1.421 0.1 - 82.6 3 2 0 -0.0012 13 0 0 0 0.00E+00 0.00E+00 - - - 0.4679 0.9382 230117_WJC_METTL3_WT_vs_EV_F04.21459.21459.2 4.88E-05 26-Sep K.VLLVGADNFTLLGK[136.11].P "sp|Q7Z2W9|RM21_HUMAN,tr|H3BUY0|H3BUY0_HUMAN,tr|F5H7V8|F5H7V8_HUMAN" 3 1466.8588 -1 35422 21459 2 1466.857124 734.4367 "39S ribosomal protein L21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL21 PE=1 SV=2" 5.81 3913.4 - 487723 - - - -1.1535 - 2.049 0.47 - 133.4 1 1 0 -0.0017 14 0 0 0 0.00E+00 0.00E+00 - - - 4.312 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.21466.21466.2 0.163 14-Aug K.ENLLDFIK[136.11].H "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 998.5528 2.26 35428 21466 2 998.552262 500.2837 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.37 3914.1 - 2.38E+06 - - - -0.5358 - 1.746 0.217 - 265.4 1 2 0 -0.0005 8 0 0 0 8.44E+07 3.74E+07 - - - 2.3245 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.21469.21469.2 0.00137 14-Aug K.LYDFYLFK.C sp|Q2TAL8|QRIC1_HUMAN 1 1107.5641 3.41 35431 21469 2 1107.563844 554.7893 Transcriptional regulator QRICH1 OS=Homo sapiens OX=9606 GN=QRICH1 PE=1 SV=1 5.83 3914.3 - 941589 - - - -0.2167 - 1.433 0.429 - 159.4 1 2 0 -0.0002 8 0 0 0 4.41E+06 1.29E+06 - - - 3.2946 0.9822 230117_WJC_METTL3_WT_vs_EV_F04.21483.21483.2 0.126 22-Jul R.LNMGEIETLDDY.- "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1411.6177 - 35443 21483 2 1411.614192 706.8161 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 3.43 3915.9 - 0 - - - -2.4936 - 1.225 0.261 - 136.4 1 2 0 -0.0035 12 0 0 0 - - - - - 1.5016 0.999 230117_WJC_METTL3_WT_vs_EV_F04.21485.21485.2 0.000651 24-Oct K.VLEFLASSFEVSR[166.11].H "sp|Q15269|PWP2_HUMAN,tr|A0A096LPI6|A0A096LPI6_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN" 3 1492.7801 -1 35445 21485 2 1492.77928 747.3973 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 4.53 3916.2 - 110042 - - - -0.5594 - 1.71 0.39 - 133.7 1 2 0 -0.0008 13 0 0 0 0.00E+00 0.00E+00 - - - 3.2982 0.9938 230117_WJC_METTL3_WT_vs_EV_F04.21488.21488.2 0.165 24-Jul K.QLLDSGLPSLLVR[166.11].S "sp|Q9NR09|BIRC6_HUMAN,tr|A0A3B3IUB9|A0A3B3IUB9_HUMAN" 2 1419.8325 -1 35448 21488 2 1419.831305 710.9235 Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=BIRC6 PE=1 SV=2 5.84 3916.6 - 0 - - - -0.8311 - 1.37 0.224 - 130.1 1 2 0 -0.0012 13 0 0 0 0.00E+00 0.00E+00 - - - 1.5031 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.21496.21496.2 0.00148 14-Aug R.ILEFFGLK.K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 965.5586 2.14 35454 21496 2 965.558372 483.7866 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3917.7 - 1.93E+07 - - - -0.2413 - 1.577 0.441 - 176.5 1 2 0 -0.0002 8 0 0 0 7.87E+07 3.69E+07 - - - 3.672 0.9969 230117_WJC_METTL3_WT_vs_EV_F04.21498.21498.2 0.00773 14-Aug R.ILEFFGLK[136.11].K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 973.5728 2.14 35456 21498 2 973.57105 487.7937 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3917.7 - 9.11E+06 - - - -1.8026 - 1.738 0.284 - 176.9 1 2 0 -0.0018 8 0 0 0 7.87E+07 3.69E+07 - - - 2.8051 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21499.21499.2 2.89E-05 22-Oct R.LLFPAVDDNLLK.F "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1356.7653 1.72 35457 21499 2 1356.764114 679.3899 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 4.21 3917.8 - 6.26E+06 - - - -0.8763 - 1.943 0.485 - 330 1 2 0 -0.0012 12 0 0 0 2.01E+07 1.17E+07 - - - 4.3705 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.21500.21500.2 0.000712 20-Jun K.AFVDFLSDEIK.E sp|Q07021|C1QBP_HUMAN 1 1282.6445 1.62 35458 21500 2 1282.642284 642.3295 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.03 3917.8 - 6.15E+06 - - - -1.7425 - 1.572 0.402 - 85.4 1 2 0 -0.0022 11 0 0 0 1.93E+07 1.19E+07 - - - 3.2332 1 230117_WJC_METTL3_WT_vs_EV_F04.21501.21501.2 5.54E-07 26-Nov R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.13 35459 21501 2 1470.879138 736.4478 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3917.9 - 5.39E+06 - - - -1.2666 - 2.352 0.614 - 275.7 1 2 0 -0.0019 14 0 0 0 2.43E+08 2.15E+08 - - - 5.7217 1 230117_WJC_METTL3_WT_vs_EV_F04.21502.21502.2 0.000112 13/26 R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.13 35460 21502 2 1478.89437 740.4549 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3917.9 - 5.18E+06 - - - -0.5619 - 2.573 0.604 - 434 1 2 0 -0.0008 14 0 0 0 2.43E+08 2.15E+08 - - - 5.8735 1 230117_WJC_METTL3_WT_vs_EV_F04.21505.21505.2 0.00144 18-Oct R.LSQSLLELWR.R "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1243.6925 1.23 35463 21505 2 1243.694052 622.8535 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 6 3918.1 - 3.39E+06 - - - 1.2704 - 2.32 0.435 - 435 1 2 0 0.0016 10 0 0 0 1.41E+07 1.14E+07 - - - 4.6025 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.21506.21506.2 0.13 16-Jul K.EVNLVLLLK.N "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1039.6641 999 35464 21506 2 1039.66443 520.8393 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 6.1 3918.1 - 3.33E+06 - - - 0.2866 - 1.56 0.294 - 212.7 1 2 0 0.0003 9 0 0 0 9.95E+06 0.00E+00 - - - 2.4989 0.9035 230117_WJC_METTL3_WT_vs_EV_F04.21515.21515.2 0.0207 16-May K.FLQLC[160.03]IFPR.C "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN,tr|H0Y815|H0Y815_HUMAN" 3 1192.6427 0.77 35473 21515 2 1192.636877 597.3286 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 8.25 3919 - 0 - - - -4.8707 - 1.358 0.182 - 58.5 1 2 0 -0.0058 9 0 0 0 1.74E+06 2.26E+06 - - - 1.2687 1 230117_WJC_METTL3_WT_vs_EV_F04.21517.21517.2 0.00138 18-Nov R.IQFFAIEIAR.N sp|Q9BVG4|PBDC1_HUMAN 1 1206.6761 4.04 35474 21517 2 1206.677609 604.3453 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 6 3919.2 - 211673 - - - 1.2555 - 2.298 0.45 - 399.6 1 2 0 0.0015 10 0 0 0 8.95E+06 2.21E+06 - - - 4.6867 1 230117_WJC_METTL3_WT_vs_EV_F04.21522.21522.2 3.96E-06 13/22 K.WLAPDGLIFPDR[166.11].A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1408.7379 0.88 35478 21522 2 1408.738363 705.3762 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3919.6 - 1.07E+06 - - - 0.3599 - 2.773 0.511 - 574.6 1 2 0 0.0005 12 0 0 0 1.08E+08 1.22E+08 - - - 5.4987 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21526.21526.2 0.00328 18-Nov R.SLGPVELLLR[166.11].G "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1105.6735 2.31 35482 21526 2 1105.673283 553.844 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.72 3920.1 - 373348 - - - -0.1646 - 1.976 0.477 - 356.8 1 2 0 -0.0002 10 0 0 0 1.03E+07 4.45E+06 - - - 4.4652 1 230117_WJC_METTL3_WT_vs_EV_F04.21528.21528.2 1.42E-07 17/26 K.TALALAIAQELGSK.V "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1384.7926 2.49 35484 21528 2 1384.79115 693.4036 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 5.66 3920.4 - 287158 - - - -1.0326 - 3.395 0.599 - 1246.7 1 2 0 -0.0014 14 0 0 0 3.40E+06 1.37E+06 - - - 6.5321 1 230117_WJC_METTL3_WT_vs_EV_F04.21532.21532.2 3.67E-07 22-Oct R.YFPTQALNFAFK.D "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 1445.7343 1.18 35487 21532 2 1445.734583 723.8744 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.59 3920.9 - 3.08E+06 - - - 0.1702 - 2.075 0.568 - 322.9 1 2 0 0.0002 12 0 0 0 1.50E+08 1.27E+08 - - - 5.1568 1 230117_WJC_METTL3_WT_vs_EV_F04.21534.21534.2 2.65E-07 14/22 K.WLAPDGLIFPDR.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1398.7296 0.88 35488 21534 2 1398.730294 700.3721 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3921.2 - 5.22E+06 - - - 0.5062 - 2.782 0.524 - 776.2 1 2 0 0.0007 12 0 0 0 1.08E+08 1.22E+08 - - - 5.6032 1 230117_WJC_METTL3_WT_vs_EV_F04.21537.21537.3 3.00E-08 18/52 R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.21 35491 21537 3 1478.89736 493.9723 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3921.4 - 1.77E+06 - - - 1.4599 - 2.612 0.574 - 415.2 1 2 0 0.0022 14 0 0 0 2.60E+07 2.15E+07 - - - 7.4905 0.9956 230117_WJC_METTL3_WT_vs_EV_F04.21538.21538.2 0.0023 14-Aug R.SWLLPVIR[166.11].D sp|Q5JTH9|RRP12_HUMAN 1 992.6047 1.19 35492 21538 2 992.60643 497.3096 RRP12-like protein OS=Homo sapiens OX=9606 GN=RRP12 PE=1 SV=2 9.47 3921.6 - 1.40E+06 - - - 1.7862 - 1.485 0.118 - 370.3 1 2 0 0.0018 8 0 0 0 6.57E+06 5.53E+06 - - - 1.1045 1 230117_WJC_METTL3_WT_vs_EV_F04.21539.21539.2 1.18E-05 13/20 Q.AFADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1170.7012 8.27 35493 21539 2 1170.70294 586.3579 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3921.7 - 864664 - - - 1.447 - 2.145 0.545 - 429.4 1 1 0 0.0017 11 0 0 0 9.23E+06 1.12E+06 - - - 5.1303 1 230117_WJC_METTL3_WT_vs_EV_F04.21540.21540.2 2.28E-10 18/30 K.LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1793.9075 0.95 35494 21540 2 1793.908209 897.961 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3921.8 - 816764 - - - 0.3952 - 3.134 0.569 - 890.8 1 2 0 0.0007 16 0 0 0 4.08E+07 4.29E+07 - - - 6.0518 1 230117_WJC_METTL3_WT_vs_EV_F04.21541.21541.2 2.99E-10 16/30 K.LFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1783.8992 0.95 35495 21541 2 1783.899587 892.9569 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3922 - 711916 - - - 0.2001 - 3.129 0.6 - 691.7 1 2 0 0.0004 16 0 0 0 4.08E+07 4.29E+07 - - - 6.277 0.8538 230117_WJC_METTL3_WT_vs_EV_F04.21543.21543.2 0.897 26-Jun R.RHHGPDVPVILGK[136.11]R.L sp|Q6UXX5|ITIH6_HUMAN 1 1587.9201 - 35497 21543 2 1587.924765 794.9673 Inter-alpha-trypsin inhibitor heavy chain H6 OS=Homo sapiens OX=9606 GN=ITIH6 PE=1 SV=1 10.84 3922.2 - 558504 - - - 2.9202 - 1.091 0.047 - 49.3 20 2 0 0.0046 14 0 0 0 - - - - - -0.9759 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21545.21545.2 0.185 24-Dec R.LGPLLLDPSLAVR[166.11].E sp|Q7Z4Q2|HEAT3_HUMAN 1 1372.8318 1.49 35499 21545 2 1372.831868 687.4232 HEAT repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=HEATR3 PE=1 SV=2 5.84 3922.5 - 504566 - - - 0.0809 - 2.18 0.285 - 400.1 1 2 0 0.0001 13 0 0 0 5.23E+06 3.51E+06 - - - 3.1461 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21548.21548.2 2.22E-05 28-Dec R.ELALALQEALEPAVR.L sp|Q5RKV6|EXOS6_HUMAN 1 1621.9039 1.05 35502 21548 2 1621.904871 811.9592 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 4.25 3922.9 - 408297 - - - 0.5851 - 2.342 0.466 - 374.6 1 2 0 0.0009 15 0 0 0 5.79E+06 5.51E+06 - - - 4.5748 0.9959 230117_WJC_METTL3_WT_vs_EV_F04.21551.21551.2 0.187 18-Jun R.LLVPILLPEK[136.11].C "sp|O75352|MPU1_HUMAN,tr|J3KSI4|J3KSI4_HUMAN,tr|J3KTK8|J3KTK8_HUMAN,tr|I3L1D2|I3L1D2_HUMAN,tr|I3L295|I3L295_HUMAN,tr|J3KT75|J3KT75_HUMAN,tr|J3QRD5|J3QRD5_HUMAN,tr|J3QS48|J3QS48_HUMAN,tr|J3QW43|J3QW43_HUMAN,tr|I3L261|I3L261_HUMAN,tr|I3L4E0|I3L4E0_HUMAN,tr|J3QQZ4|J3QQZ4_HUMAN,tr|I3L405|I3L405_HUMAN,tr|I3L4T1|I3L4T1_HUMAN" 14 1141.7566 1.66 35505 21551 2 1141.75686 571.8856 Mannose-P-dolichol utilization defect 1 protein OS=Homo sapiens OX=9606 GN=MPDU1 PE=1 SV=2 6 3923.3 - 331027 - - - 0.2426 - 1.167 0.252 - 46 1 2 0 0.0003 10 0 0 0 1.91E+06 1.15E+06 - - - 1.3333 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21553.21553.2 0.000241 20-Sep K.LDTSQWPLLLK[136.11].N "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1320.7533 0.78 35507 21553 2 1320.756469 661.3839 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 5.84 3923.5 - 304205 - - - 2.4085 - 1.907 0.424 - 353.4 1 2 0 0.0032 11 0 0 0 9.67E+06 1.23E+07 - - - 3.918 1 230117_WJC_METTL3_WT_vs_EV_F04.21555.21555.2 1.31E-05 14/26 K.TYVLNPLAPEFIPR[166.11].A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1638.9009 2.72 35508 21555 2 1638.900038 820.4577 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.66 3923.8 - 95106.2 - - - -0.5254 - 2.504 0.555 - 652.1 1 2 0 -0.0009 14 0 0 0 1.03E+07 3.78E+06 - - - 5.4434 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.21566.21566.2 0.00145 20-Sep K.LDTSQWPLLLK.N "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1312.7391 0.77 35519 21566 2 1312.737535 657.3768 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 5.84 3924.8 - 0 - - - -1.183 - 2.099 0.416 - 263.2 1 2 0 -0.0016 11 0 0 0 9.54E+06 1.23E+07 - - - 4.1189 1 230117_WJC_METTL3_WT_vs_EV_F04.21570.21570.3 7.42E-09 14/52 R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.21 35521 21570 3 1470.884464 491.3009 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3925.3 - 1.04E+07 - - - 2.3544 - 2.685 0.601 - 252.9 1 2 0 0.0035 14 0 0 0 2.60E+07 2.15E+07 - - - 7.8644 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.21572.21572.2 0.0332 18-Apr R.VVTDLISLIR.Q sp|P38432|COIL_HUMAN 1 1127.6914 1.1 35523 21572 2 1127.691745 564.853 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3925.4 - 1.16E+07 - - - 0.2971 - 0.906 0.399 - 50 1 2 0 0.0003 10 0 0 0 2.38E+07 2.17E+07 - - - 1.7124 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21573.21573.2 0.000899 18-Jul R.VVTDLISLIR[166.11].Q sp|P38432|COIL_HUMAN 1 1137.6997 1.1 35524 21573 2 1137.699877 569.8571 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3925.5 - 1.12E+07 - - - 0.1732 - 1.503 0.499 - 179.7 1 2 0 0.0002 10 0 0 0 2.38E+07 2.17E+07 - - - 3.8639 0.9879 230117_WJC_METTL3_WT_vs_EV_F04.21575.21575.2 0.534 16-Jul R.FYELLVTGR.Y "sp|Q9UPS6|SET1B_HUMAN,tr|A0A0A0MQV9|A0A0A0MQV9_HUMAN" 2 1096.5917 18.96 35526 21575 2 1096.591397 549.3031 Histone-lysine N-methyltransferase SETD1B OS=Homo sapiens OX=9606 GN=SETD1B PE=1 SV=3 6 3925.5 - 5.89E+06 - - - -0.2727 - 1.296 0.126 - 201.3 1 2 0 -0.0003 9 0 0 0 1.37E+07 7.21E+05 - - - 0.7217 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.21579.21579.3 0.000146 Dec-40 K.LPLGLLLHPFR.D sp|O95487|SC24B_HUMAN 1 1274.7863 -1 35530 21579 3 1274.785762 425.936 Protein transport protein Sec24B OS=Homo sapiens OX=9606 GN=SEC24B PE=1 SV=2 9.76 3925.8 - 3.48E+06 - - - -0.4322 - 2.344 0.214 - 221.2 1 2 0 -0.0006 11 0 0 0 0.00E+00 0.00E+00 - - - 3.3457 1 230117_WJC_METTL3_WT_vs_EV_F04.21581.21581.2 5.23E-05 26-Jul K.TYVLNPLAPEFIPR.A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1628.8926 2.72 35532 21581 2 1628.89502 815.4536 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.66 3925.9 - 2.89E+06 - - - 1.4679 - 1.789 0.563 - 125.2 1 2 0 0.0024 14 0 0 0 1.03E+07 3.78E+06 - - - 4.6582 0.9022 230117_WJC_METTL3_WT_vs_EV_F04.21582.21582.3 0.00748 14/72 K.LLHHLSDLALTLPTDAVSI.C "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2028.1255 - 35533 21582 3 2028.13001 677.0491 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.05 3926 - 2.80E+06 - - - 2.203 - 2.392 0.325 - 191.7 1 1 0 0.0045 19 0 0 0 - - - - - 4.3048 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21586.21586.2 0.000529 18-Sep K.FLDVLELAEK.F "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1175.6438 1.13 35537 21586 2 1175.642683 588.8292 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.14 3926.2 - 2.12E+06 - - - -0.9425 - 2.015 0.467 - 185.9 1 2 0 -0.0011 10 0 0 0 4.86E+06 4.30E+06 - - - 4.4456 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21589.21589.2 0.000719 20-Oct R.LFEFAGYDVLR[166.11].L sp|P54136|SYRC_HUMAN 1 1338.6848 1.33 35540 21589 2 1338.684656 670.3497 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3926.4 - 1.94E+06 - - - -0.0762 - 2.191 0.432 - 329.2 1 2 0 -0.0001 11 0 0 0 1.56E+07 1.17E+07 - - - 4.3536 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21594.21594.2 0.0237 18-Oct R.DAVLLLFANK.Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1102.6386 2.19 35544 21594 2 1102.641656 552.3266 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3926.9 - 2.89E+06 - - - 2.7298 - 2.229 0.349 - 462.4 1 2 0 0.003 10 0 0 0 1.66E+07 7.58E+06 - - - 3.8551 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.21596.21596.2 0.00097 16-Jul R.GYPTLLLFR[166.11].G sp|Q8NBS9|TXND5_HUMAN 1 1088.6258 1.8 35546 21596 2 1088.629676 545.3202 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 8.75 3927.1 - 1.44E+06 - - - 3.5733 - 1.53 0.373 - 188.8 1 2 0 0.0039 9 0 0 0 1.30E+07 7.22E+06 - - - 3.0251 0.9858 230117_WJC_METTL3_WT_vs_EV_F04.21597.21597.3 0.0784 Nov-40 K.IR[166.11]FLILPDMLK[136.11].N sp|P62318|SMD3_HUMAN 1 1375.838 -1 35547 21597 3 1375.839464 459.62 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 8.75 3927.3 - 1.40E+06 - - - 1.0394 - 1.94 0.384 - 186.9 1 2 1 0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 4.7034 0.9873 230117_WJC_METTL3_WT_vs_EV_F04.21599.21599.3 0.0807 Dec-40 K.IRFLILPDMLK.N sp|P62318|SMD3_HUMAN 1 1357.8156 -1 35549 21599 3 1357.81738 453.6125 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 8.75 3927.5 - 1.37E+06 - - - 1.3374 - 2.156 0.368 - 317.6 1 2 1 0.0018 11 0 0 0 0.00E+00 0.00E+00 - - - 4.8248 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21600.21600.2 0.0429 18-Oct R.DAVLLLFANK[136.11].Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1110.6528 2.19 35550 21600 2 1110.654542 556.3337 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3927.6 - 1.26E+06 - - - 1.527 - 2.284 0.416 - 398.4 1 2 0 0.0017 10 0 0 0 1.66E+07 7.58E+06 - - - 4.4185 0.9951 230117_WJC_METTL3_WT_vs_EV_F04.21607.21607.2 0.225 26-May R.LAQVSPELLLASVR.R sp|O43592|XPOT_HUMAN 1 1494.877 1.37 35557 21607 2 1494.881169 748.4458 Exportin-T OS=Homo sapiens OX=9606 GN=XPOT PE=1 SV=2 6 3928.6 - 598989 - - - 2.8029 - 1.276 0.234 - 59.6 1 2 0 0.0042 14 0 0 0 3.84E+06 2.79E+06 - - - 1.3796 0.9457 230117_WJC_METTL3_WT_vs_EV_F04.21609.21609.3 0.178 Jun-76 R.LFPPWIK[136.11]PADTEPPPLLVYK[136.11].W "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 2336.3155 -1 35559 21609 3 2336.318983 779.7791 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.07 3928.8 - 596870 - - - 1.4788 - 1.428 0.105 - 36.3 2 2 0 0.0035 20 0 0 0 0.00E+00 0.00E+00 - - - 0.4347 1 230117_WJC_METTL3_WT_vs_EV_F04.21616.21616.2 0.000207 20-Nov R.LFEFAGYDVLR.L sp|P54136|SYRC_HUMAN 1 1328.6765 1.33 35565 21616 2 1328.677385 665.3455 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3929.5 - 2.93E+06 - - - 0.6751 - 2.343 0.555 - 471.9 1 2 0 0.0009 11 0 0 0 1.56E+07 1.17E+07 - - - 5.4433 1 230117_WJC_METTL3_WT_vs_EV_F04.21618.21618.2 3.49E-10 15/30 R.IIGATDSSGELMFLMK.W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1711.8525 -1 35567 21618 2 1711.85306 856.9335 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3929.7 - 1.05E+06 - - - 0.3388 - 3.261 0.654 - 505.3 1 2 0 0.0006 16 0 0 0 0.00E+00 0.00E+00 - - - 6.7773 1 230117_WJC_METTL3_WT_vs_EV_F04.21624.21624.2 0.000843 18-Oct R.DALLLIFANK.Q "sp|P36406|TRI23_HUMAN,sp|P62330|ARF6_HUMAN" 2 1116.6543 1.67 35573 21624 2 1116.655065 559.3344 E3 ubiquitin-protein ligase TRIM23 OS=Homo sapiens OX=9606 GN=TRIM23 PE=1 SV=1 5.84 3930.4 - 575335 - - - 0.6887 - 2.276 0.442 - 283.2 1 2 0 0.0008 10 0 0 0 1.01E+07 6.02E+06 - - - 4.601 0.9934 230117_WJC_METTL3_WT_vs_EV_F04.21625.21625.2 0.0844 16-Sep K.APWELLELR.V "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A6Q8PF15|A0A6Q8PF15_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN,tr|A0A6Q8PFC1|A0A6Q8PFC1_HUMAN" 6 1125.6182 0.88 35574 21625 2 1125.618838 563.8164 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.53 3930.6 - 573382 - - - 0.5268 - 1.314 0.142 - 131.7 1 2 0 0.0006 9 0 0 0 7.57E+06 8.58E+06 - - - 0.8796 1 230117_WJC_METTL3_WT_vs_EV_F04.21627.21627.2 0.00447 20-Dec K.VTDLLGGLFSK[136.11].T "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1156.6583 -1 35576 21627 2 1156.659411 579.3364 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.81 3930.8 - 499709 - - - 0.9389 - 2.733 0.383 - 761.6 1 2 0 0.0011 11 0 0 0 0.00E+00 0.00E+00 - - - 4.5893 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21628.21628.2 0.000432 16-Sep K.APWELLELR[166.11].V "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A6Q8PF15|A0A6Q8PF15_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN,tr|A0A6Q8PFC1|A0A6Q8PFC1_HUMAN" 6 1135.6265 0.88 35577 21628 2 1135.626684 568.8205 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.53 3930.9 - 495362 - - - 0.1488 - 1.797 0.447 - 264.8 1 2 0 0.0002 9 0 0 0 7.72E+06 8.74E+06 - - - 4.0382 1 230117_WJC_METTL3_WT_vs_EV_F04.21637.21637.2 7.27E-09 13/24 K.SVDPTLALSVYLR[166.11].A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1442.8009 -1 35585 21637 2 1442.801768 722.4077 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.55 3932 - 1.95E+06 - - - 0.6363 - 2.642 0.611 - 575.1 1 2 0 0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 6.047 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21639.21639.2 0.000112 20-Oct R.FLEEFITPIVK.V "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 1334.7486 1.18 35587 21639 2 1334.749619 668.3816 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.53 3932.3 - 1.64E+06 - - - 0.7709 - 2.004 0.431 - 212.2 1 2 0 0.001 11 0 0 0 7.27E+06 6.17E+06 - - - 4.1046 1 230117_WJC_METTL3_WT_vs_EV_F04.21641.21641.2 2.47E-07 20-Dec R.VINQMLEFAFR.Y "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 1366.7067 -1 35589 21641 2 1366.70832 684.3606 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 5.97 3932.4 - 1.43E+06 - - - 1.1546 - 2.638 0.555 - 549.4 1 2 0 0.0016 11 0 0 0 0.00E+00 0.00E+00 - - - 5.7639 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.21642.21642.2 0.0462 18-Aug R.GLIPVFALGR[166.11].A "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1051.6418 -1 35590 21642 2 1051.642161 526.8282 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 9.75 3932.6 - 1.17E+06 - - - 0.3708 - 1.555 0.296 - 116.5 1 2 0 0.0004 10 0 0 0 0.00E+00 0.00E+00 - - - 2.4594 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21644.21644.3 9.61E-05 Dec-60 R.IIGATDSSGELMFLMK.W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1711.8525 -1 35592 21644 3 1711.854903 571.6248 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3932.8 - 865996 - - - 1.4154 - 2.222 0.257 - 179.7 1 2 0 0.0024 16 0 0 0 0.00E+00 0.00E+00 - - - 3.4532 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.21645.21645.2 0.000101 26-Sep R.ILLDIDNDTESTAL.- sp|Q68EM7|RHG17_HUMAN 1 1531.7617 - 35593 21645 2 1531.759556 766.8881 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 3.37 3932.9 - 610999 - - - -1.4219 - 2.112 0.433 - 202.7 1 2 0 -0.0022 14 0 0 0 - - - - - 4.1146 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.21647.21647.2 0.0243 20-Oct R.FFPLESWQIGK[136.11].L "sp|P30046|DOPD_HUMAN,tr|J3KQ18|J3KQ18_HUMAN,tr|H7C342|H7C342_HUMAN" 3 1358.7114 1.28 35595 21647 2 1358.713979 680.363 D-dopachrome decarboxylase OS=Homo sapiens OX=9606 GN=DDT PE=1 SV=3 6 3933.2 - 530649 - - - 1.8812 - 1.452 0.227 - 106.4 1 2 0 0.0026 11 0 0 0 3.70E+06 2.90E+06 - - - 1.7257 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.21651.21651.2 0.000221 30-Nov K.IIGATDSC[160.03]GDLMFLMK[136.11].W sp|P45973|CBX5_HUMAN 1 1778.8497 -1 35599 21651 2 1778.848489 890.4321 Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1 4.21 3933.7 - 406640 - - - -0.6527 - 1.916 0.417 - 167.5 1 2 0 -0.0012 16 0 0 0 0.00E+00 0.00E+00 - - - 3.7192 1 230117_WJC_METTL3_WT_vs_EV_F04.21654.21654.2 2.57E-09 13/30 R.IIGATDSSGELMFLMK[136.11].W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1719.8667 1.31 35601 21654 2 1719.867366 860.9406 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3934 - 384924 - - - 0.3989 - 2.789 0.622 - 306.2 1 2 0 0.0007 16 0 0 0 1.08E+07 8.22E+06 - - - 6.1566 1 230117_WJC_METTL3_WT_vs_EV_F04.21658.21658.2 2.55E-10 18/30 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 -1 35605 21658 2 1807.925334 904.9689 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3934.3 - 6.61E+06 - - - 1.208 - 3.318 0.597 - 1036.9 1 2 0 0.0022 16 0 0 0 0.00E+00 0.00E+00 - - - 6.3984 1 230117_WJC_METTL3_WT_vs_EV_F04.21659.21659.2 9.57E-10 19/30 K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 -1 35606 21659 2 1797.91622 899.9647 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3934.3 - 5.25E+06 - - - 0.7453 - 3.488 0.626 - 1182.2 1 2 0 0.0013 16 0 0 0 0.00E+00 0.00E+00 - - - 6.7357 1 230117_WJC_METTL3_WT_vs_EV_F04.21660.21660.2 1.73E-05 20-Nov K.YPSPFFVFGEK.L sp|Q08211|DHX9_HUMAN 1 1316.6441 0.98 35607 21660 2 1316.645604 659.3293 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3934.4 - 3.64E+06 - - - 1.1233 - 2.252 0.462 - 491.4 1 2 0 0.0015 11 0 0 0 7.90E+07 8.09E+07 - - - 4.649 1 230117_WJC_METTL3_WT_vs_EV_F04.21661.21661.2 8.93E-08 22-Nov R.FSTFFDDAPVFR.L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1447.6772 -1 35608 21661 2 1447.678622 724.8459 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3934.4 - 2.32E+06 - - - 0.9712 - 2.275 0.631 - 392 1 2 0 0.0014 12 0 0 0 0.00E+00 0.00E+00 - - - 5.8639 1 230117_WJC_METTL3_WT_vs_EV_F04.21666.21666.2 2.34E-05 13/22 R.FSTFFDDAPVFR[166.11].L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1457.6855 -1 35613 21666 2 1457.686809 729.85 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3934.8 - 1.08E+06 - - - 0.9076 - 2.379 0.53 - 535.8 1 2 0 0.0013 12 0 0 0 0.00E+00 0.00E+00 - - - 5.2355 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21667.21667.2 0.044 20-Sep R.FLDELDAVQMD.- "sp|O15160|RPAC1_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 3 1294.5751 - 35614 21667 2 1294.576349 648.2948 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 3.59 3934.9 - 975022 - - - 0.9501 - 1.896 0.437 - 215.7 1 2 0 0.0012 11 0 0 0 - - - - - 3.999 1 230117_WJC_METTL3_WT_vs_EV_F04.21669.21669.2 8.47E-07 16/24 K.LVSDEMVVELIEK.N "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 5 1502.7902 -1 35616 21669 2 1502.791629 752.4024 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 4 3935.1 - 775401 - - - 0.9529 - 2.165 0.575 - 510.6 1 2 0 0.0014 13 0 0 0 0.00E+00 0.00E+00 - - - 5.2699 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21677.21677.2 0.00561 14-Jul R.GFGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 921.5204 1.1 35623 21677 2 921.521144 461.7675 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3936.1 - 1.16E+07 - - - 0.8345 - 1.365 0.449 - 143.3 1 2 0 0.0008 8 0 0 0 3.66E+08 3.34E+08 - - - 3.2955 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21678.21678.2 2.16E-05 20-Oct K.YPSPFFVFGEK[136.11].L sp|Q08211|DHX9_HUMAN 1 1324.6583 0.98 35624 21678 2 1324.659733 663.3364 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3936.1 - 1.09E+07 - - - 1.0629 - 2.088 0.426 - 334.4 1 2 0 0.0014 11 0 0 0 7.92E+07 8.09E+07 - - - 4.1786 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21679.21679.2 0.00198 14-Aug R.GFGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 913.5062 1.1 35625 21679 2 913.506947 457.7604 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3936.2 - 9.35E+06 - - - 0.8451 - 1.478 0.45 - 209.3 1 2 0 0.0008 8 0 0 0 3.66E+08 3.34E+08 - - - 3.5428 1 230117_WJC_METTL3_WT_vs_EV_F04.21680.21680.3 3.36E-07 14/60 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 -1 35626 21680 3 1807.925353 603.6483 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3936.2 - 7.35E+06 - - - 1.2185 - 2.801 0.578 - 283.9 1 2 0 0.0022 16 0 0 0 0.00E+00 0.00E+00 - - - 7.6263 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.21681.21681.3 0.00235 Dec-60 K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 -1 35627 21681 3 1797.91913 600.3122 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3936.3 - 6.24E+06 - - - 2.3638 - 2.276 0.447 - 156.7 1 2 0 0.0043 16 0 0 0 0.00E+00 0.00E+00 - - - 5.6326 1 230117_WJC_METTL3_WT_vs_EV_F04.21682.21682.2 2.88E-07 17/24 K.TPFLLVGTQIDLR.D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1471.8399 1.37 35628 21682 2 1471.841217 736.9272 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3936.3 - 3.27E+06 - - - 0.9186 - 3.132 0.631 - 1297.2 1 2 0 0.0014 13 0 0 0 9.76E+06 7.10E+06 - - - 6.6313 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21683.21683.2 0.0019 16-Sep K.GVIDLIFEK.A "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 1032.5855 -1 35629 21683 2 1032.586306 517.3001 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 3936.4 - 1.71E+06 - - - 0.7341 - 1.729 0.404 - 196.7 1 2 0 0.0008 9 0 0 0 0.00E+00 0.00E+00 - - - 3.6088 1 230117_WJC_METTL3_WT_vs_EV_F04.21684.21684.2 0.000145 20-Oct R.IFGLLMGTLQK[136.11].F sp|Q9H307|PININ_HUMAN 1 1227.7141 1.13 35630 21684 2 1227.716587 614.8643 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3936.4 - 1.57E+06 - - - 2.0534 - 2.06 0.488 - 247 1 2 0 0.0025 11 0 0 0 4.13E+07 3.66E+07 - - - 4.5997 1 230117_WJC_METTL3_WT_vs_EV_F04.21686.21686.2 3.15E-05 15/24 N.IVGLVGVDQFLVK.T sp|P13639|EF2_HUMAN 1 1385.8282 -1 35632 21686 2 1385.830004 693.9214 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3936.6 - 1.48E+06 - - - 1.2743 - 2.855 0.553 - 532.3 1 1 0 0.0018 13 0 0 0 0.00E+00 0.00E+00 - - - 5.8174 1 230117_WJC_METTL3_WT_vs_EV_F04.21687.21687.2 4.65E-07 30-Dec K.LFIGGLSFETTDDSLR.E "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1769.8836 -1 35633 21687 2 1769.897575 885.9491 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.03 3936.7 - 1.20E+06 - - - 7.9073 - 2.517 0.494 - 375.1 1 2 0 0.014 16 0 0 0 0.00E+00 0.00E+00 - - - 4.9547 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21688.21688.2 0.0115 16-Aug K.LLELDSFLK.E "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|K9J957|K9J957_HUMAN,tr|B7Z8D3|B7Z8D3_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 5 1076.6118 -1 35634 21688 2 1076.612913 539.3132 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.37 3936.8 - 1.20E+06 - - - 1.0691 - 1.633 0.321 - 127.8 1 2 0 0.0012 9 0 0 0 0.00E+00 0.00E+00 - - - 2.8304 1 230117_WJC_METTL3_WT_vs_EV_F04.21689.21689.2 1.51E-08 17/30 K.LFIGGLSFETTDDSLR[166.11].E "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1779.8918 -1 35635 21689 2 1779.893105 890.9532 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.03 3936.9 - 1.16E+06 - - - 0.7051 - 3.193 0.575 - 809.6 1 2 0 0.0013 16 0 0 0 0.00E+00 0.00E+00 - - - 6.1418 1 230117_WJC_METTL3_WT_vs_EV_F04.21690.21690.3 2.00E-05 16/48 K.TPFLLVGTQIDLR.D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1471.8399 -1 35636 21690 3 1471.842706 491.6206 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3937 - 1.14E+06 - - - 1.9302 - 2.883 0.473 - 319.5 1 2 0 0.0028 13 0 0 0 0.00E+00 0.00E+00 - - - 6.6835 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21693.21693.2 2.30E-05 20-Oct K.FIWSEISYLSK.W sp|Q16706|MA2A1_HUMAN 1 1371.7075 1.19 35639 21693 2 1371.707762 686.861 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 6 3937.4 - 923425 - - - 0.2245 - 1.972 0.416 - 297.1 1 2 0 0.0003 11 0 0 0 2.96E+06 2.49E+06 - - - 3.9505 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21696.21696.2 0.00153 18-Sep K.SLESFVELMK.T sp|Q6KB66|K2C80_HUMAN 1 1181.6002 -1 35641 21696 2 1181.603549 591.8074 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 4.53 3937.7 - 1.26E+06 - - - 2.825 - 1.98 0.412 - 184.1 1 2 0 0.0033 10 0 0 0 0.00E+00 0.00E+00 - - - 3.9897 1 230117_WJC_METTL3_WT_vs_EV_F04.21697.21697.2 1.19E-05 22-Nov K.LNTLETEEWFFK.D "sp|P07948|LYN_HUMAN,tr|E5RJ37|E5RJ37_HUMAN" 2 1555.7559 -1 35642 21697 2 1555.757837 778.8852 Tyrosine-protein kinase Lyn OS=Homo sapiens OX=9606 GN=LYN PE=1 SV=3 4.25 3937.8 - 795294 - - - 1.2701 - 2.508 0.525 - 344.2 1 2 0 0.002 12 0 0 0 0.00E+00 0.00E+00 - - - 5.3374 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21698.21698.2 0.000328 20-Sep R.ASILNTWISLK[136.11].Q "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN" 2 1252.7271 1.83 35643 21698 2 1252.730202 627.3708 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 8.8 3937.8 - 4.37E+06 - - - 2.4978 - 2.037 0.445 - 335.3 1 2 0 0.0031 11 0 0 0 1.55E+07 8.44E+06 - - - 4.2515 1 230117_WJC_METTL3_WT_vs_EV_F04.21699.21699.2 2.50E-05 24-Dec N.IVGLVGVDQFLVK[136.11].T sp|P13639|EF2_HUMAN 1 1393.8424 -1 35644 21699 2 1393.842069 697.9285 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3937.9 - 1.82E+06 - - - -0.2647 - 2.356 0.521 - 426.2 1 1 0 -0.0004 13 0 0 0 0.00E+00 0.00E+00 - - - 5.0884 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.21702.21702.2 0.000625 18-Oct K.FLLLQGLVEK[136.11].E "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 1166.7154 -1 35647 21702 2 1166.714014 584.365 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 6 3938.1 - 1.63E+06 - - - -1.2274 - 1.971 0.377 - 261.8 1 2 0 -0.0014 10 0 0 0 0.00E+00 0.00E+00 - - - 3.7191 1 230117_WJC_METTL3_WT_vs_EV_F04.21706.21706.2 0.000292 12-Sep G.FGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 856.4847 1.06 35651 21706 2 856.484967 429.2496 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3938.4 - 1.24E+06 - - - 0.2989 - 1.962 0.464 - 226.9 1 1 0 0.0003 7 0 0 0 3.30E+06 3.10E+06 - - - 4.6035 0.9967 230117_WJC_METTL3_WT_vs_EV_F04.21707.21707.2 0.143 22-Aug K.YDNMAELFAVVK.T "sp|Q9UK41|VPS28_HUMAN,tr|E9PR04|E9PR04_HUMAN,tr|E9PQR7|E9PQR7_HUMAN,tr|E9PM90|E9PM90_HUMAN" 4 1398.6853 -1 35652 21707 2 1398.68622 700.3499 Vacuolar protein sorting-associated protein 28 homolog OS=Homo sapiens OX=9606 GN=VPS28 PE=1 SV=1 4.37 3938.5 - 1.22E+06 - - - 0.6306 - 1.308 0.224 - 103.6 1 2 0 0.0009 12 0 0 0 0.00E+00 0.00E+00 - - - 1.4017 0.9762 230117_WJC_METTL3_WT_vs_EV_F04.21708.21708.2 0.0192 12-Aug G.FGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 864.4989 1.06 35653 21708 2 864.500405 433.2567 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3938.6 - 1.02E+06 - - - 1.7282 - 1.887 0.419 - 169.5 1 1 0 0.0015 7 0 0 0 3.30E+06 3.10E+06 - - - 4.1473 0.9078 230117_WJC_METTL3_WT_vs_EV_F04.21710.21710.2 0.279 14-Aug R.LLFQNLWK[136.11].P "sp|O60573|IF4E2_HUMAN,tr|B8ZZL3|B8ZZL3_HUMAN" 2 1068.6212 -1 35655 21710 2 1068.621793 535.3179 Eukaryotic translation initiation factor 4E type 2 OS=Homo sapiens OX=9606 GN=EIF4E2 PE=1 SV=1 8.75 3938.8 - 813702 - - - 0.5998 - 1.58 0.249 - 128.1 1 1 0 0.0006 8 0 0 0 0.00E+00 0.00E+00 - - - 2.2595 1 230117_WJC_METTL3_WT_vs_EV_F04.21711.21711.2 1.58E-08 30-Dec R.IMEGPAFNFLDAPAVR.V sp|P11177|ODPB_HUMAN 1 1746.8763 -1 35656 21711 2 1746.885923 874.4454 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 4.37 3938.9 - 805785 - - - 5.4932 - 2.749 0.573 - 474.3 1 2 0 0.0096 16 0 0 0 0.00E+00 0.00E+00 - - - 5.7563 0.9192 230117_WJC_METTL3_WT_vs_EV_F04.21713.21713.3 0.355 Jun-48 K.TPFLLVGTQIDLR[166.11].D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1481.8481 -1 35658 21713 3 1481.849369 494.9567 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3939.1 - 542417 - - - 0.8327 - 1.436 0.097 - 37.3 8 2 0 0.0012 13 0 0 0 0.00E+00 0.00E+00 - - - 0.1843 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.21714.21714.2 0.000103 30-Dec K.LGIWGGNVALDNLQIK.E sp|Q709C8|VP13C_HUMAN 1 1709.9465 -1 35659 21714 2 1709.952134 855.9805 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 5.84 3939.3 - 497671 - - - 3.3212 - 1.881 0.393 - 256.6 1 2 0 0.0057 16 0 0 0 0.00E+00 0.00E+00 - - - 3.4952 1 230117_WJC_METTL3_WT_vs_EV_F04.21718.21718.2 2.34E-05 13/22 K.VPGLYVIDSIVR[166.11].Q "sp|O95104|SCAF4_HUMAN,sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 3 1339.7739 -1 35662 21718 2 1339.77692 670.8942 SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3 5.81 3939.8 - 662883 - - - 2.2489 - 2.4 0.487 - 733.2 1 2 0 0.003 12 0 0 0 0.00E+00 0.00E+00 - - - 4.9405 1 230117_WJC_METTL3_WT_vs_EV_F04.21719.21719.3 0.000203 14/60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 28.82 35663 21719 3 1796.006589 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3939.8 - 7.83E+06 - - - 1.2389 - 3.085 0.476 - 333.7 1 2 0 0.0022 16 0 0 0 5.16E+07 1.79E+06 - - - 6.7369 1 230117_WJC_METTL3_WT_vs_EV_F04.21720.21720.2 8.37E-09 16/22 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 2567.66 35664 21720 2 1459.792467 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3939.8 - 7.73E+06 - - - 0.1514 - 3.166 0.584 - 1234.6 1 2 0 0.0002 12 0 0 0 5.04E+08 1.96E+05 - - - 6.3867 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21722.21722.2 0.000195 18-Nov K.FLLLQGLVEK.E "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 1158.7012 -1 35666 21722 2 1158.702017 580.3579 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 6 3939.9 - 3.88E+06 - - - 0.6654 - 2.11 0.429 - 329.3 1 2 0 0.0008 10 0 0 0 0.00E+00 0.00E+00 - - - 4.2936 1 230117_WJC_METTL3_WT_vs_EV_F04.21725.21725.2 1.65E-06 21/30 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 999 35669 21725 2 1796.005743 899.0095 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3940.2 - 1.70E+06 - - - 0.7678 - 4.005 0.635 - 1787.5 1 2 0 0.0014 16 0 0 0 1.66E+07 0.00E+00 - - - 7.142 0.9754 230117_WJC_METTL3_WT_vs_EV_F04.21726.21726.2 2.29 12-Jun K.ELFSFFR.D "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 944.4756 -1 35670 21726 2 944.475429 473.2451 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6.1 3940.3 - 1.64E+06 - - - -0.1842 - 1.177 0.085 - 152.7 1 2 0 -0.0002 7 0 0 0 0.00E+00 0.00E+00 - - - 0.1851 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21728.21728.2 0.0497 20-Dec K.LALGIPLPELR.N "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1190.7387 2.31 35672 21728 2 1190.739658 596.3766 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3940.4 - 1.54E+06 - - - 0.8096 - 2.581 0.224 - 397.6 1 2 0 0.001 11 0 0 0 1.85E+07 8.02E+06 - - - 3.2602 0.9931 230117_WJC_METTL3_WT_vs_EV_F04.21729.21729.2 0.493 12-Jun K.ELFSFFR[166.11].D "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 954.4839 -1 35673 21729 2 954.483239 478.2492 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6.1 3940.6 - 1.20E+06 - - - -0.6642 - 1.323 0.19 - 151.3 1 2 0 -0.0006 7 0 0 0 0.00E+00 0.00E+00 - - - 1.331 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.21732.21732.2 0.000599 24-Nov K.WAIAQLNYADMLK.R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1535.7806 -1 35676 21732 2 1535.781444 768.8976 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.83 3941 - 747699 - - - 0.5268 - 1.744 0.363 - 251.5 1 2 0 0.0008 13 0 0 0 0.00E+00 0.00E+00 - - - 3.1493 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.21734.21734.2 0.0404 20-Oct R.TNLANVVLLLK[136.11].S sp|Q92620|PRP16_HUMAN 1 1204.7635 0.19 35678 21734 2 1204.763062 603.389 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38 PE=1 SV=2 8.41 3941.2 - 691456 - - - -0.3295 - 1.478 0.304 - 220.7 1 2 0 -0.0004 11 0 0 0 6.18E+05 3.25E+06 - - - 2.3431 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.21735.21735.3 1.63E-07 19/44 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 62.73 35679 21735 3 1459.792015 487.6047 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3941.3 - 664236 - - - -0.1582 - 3.167 0.46 - 736.4 1 2 0 -0.0002 12 0 0 0 3.67E+07 5.86E+05 - - - 6.8638 1 230117_WJC_METTL3_WT_vs_EV_F04.21747.21747.2 0.000116 20-Sep K.VVLPTFILEPR.S "sp|Q9BZF1|OSBL8_HUMAN,tr|F8VUA7|F8VUA7_HUMAN,tr|F8VQX7|F8VQX7_HUMAN" 3 1282.7649 2.04 35690 21747 2 1282.764233 642.3897 Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3 5.97 3942.7 - 715991 - - - -0.527 - 2.073 0.499 - 295.8 1 2 0 -0.0007 11 0 0 0 3.92E+06 1.92E+06 - - - 4.6985 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21749.21749.2 0.0206 22-Nov K.VLLVLELQGLQK[136.11].N sp|Q14697|GANAB_HUMAN 1 1359.8581 -1 35692 21749 2 1359.860303 680.9363 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 5.97 3943 - 596740 - - - 1.6288 - 2.242 0.433 - 318.3 1 2 0 0.0022 12 0 0 0 0.00E+00 0.00E+00 - - - 4.3628 0.9989 230117_WJC_METTL3_WT_vs_EV_F04.21751.21751.2 1.25E-06 22-Oct K.VLLVLELQGLQK.N sp|Q14697|GANAB_HUMAN 1 1351.8439 -1 35694 21751 2 1351.848951 676.9292 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 5.97 3943.2 - 458581 - - - 3.7453 - 2.243 0.347 - 265.9 1 2 0 0.0051 12 0 0 0 0.00E+00 0.00E+00 - - - 3.7278 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21754.21754.2 0.00342 20-Sep K.VVLPTFILEPR[166.11].S "sp|Q9BZF1|OSBL8_HUMAN,tr|F8VUA7|F8VUA7_HUMAN,tr|F8VQX7|F8VQX7_HUMAN" 3 1292.7732 2.04 35697 21754 2 1292.775517 647.3939 Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3 5.97 3943.6 - 336808 - - - 1.8085 - 1.94 0.423 - 255.4 1 2 0 0.0023 11 0 0 0 3.92E+06 1.92E+06 - - - 3.9573 1 230117_WJC_METTL3_WT_vs_EV_F04.21765.21765.3 0.000561 17/72 K.VLLVGADNFTLLGKPLLGK.D "sp|Q7Z2W9|RM21_HUMAN,tr|H3BUY0|H3BUY0_HUMAN" 2 1967.1819 -1 35707 21765 3 1967.185207 656.7346 "39S ribosomal protein L21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL21 PE=1 SV=2" 8.56 3944.8 - 1.47E+06 - - - 1.6633 - 3.402 0.659 - 231.1 1 2 0 0.0033 19 0 0 0 0.00E+00 0.00E+00 - - - 8.8943 0.9945 230117_WJC_METTL3_WT_vs_EV_F04.21770.21770.2 0.028 20-Nov K.AIVEFLSNLAR[166.11].H sp|Q13112|CAF1B_HUMAN 1 1241.7007 -1 35712 21770 2 1241.705111 621.8576 Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1 6.05 3945.3 - 913646 - - - 3.5186 - 1.701 0.158 - 360.1 1 2 0 0.0044 11 0 0 0 0.00E+00 0.00E+00 - - - 1.6437 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21780.21780.2 0.000935 24-Nov R.LLDISASSTEQIL.- "sp|O43615|TIM44_HUMAN,tr|M0QXM9|M0QXM9_HUMAN" 2 1388.7399 - 35720 21780 2 1388.741764 695.3772 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.67 3946.6 - 7.88E+06 - - - 1.3595 - 2.304 0.413 - 385.7 1 2 0 0.0019 13 0 0 0 - - - - - 4.233 1 230117_WJC_METTL3_WT_vs_EV_F04.21782.21782.3 1.55E-07 14/52 K.LYSPSQIGAFVLMK.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1552.8323 3.92 35722 21782 3 1552.835337 518.6181 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3946.7 - 3.34E+06 - - - 1.932 - 2.789 0.509 - 337 1 2 0 0.003 14 0 0 0 2.34E+07 5.98E+06 - - - 6.9398 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21784.21784.2 0.000422 22-Oct R.VALILQNVDLPN.- "sp|Q04446|GLGB_HUMAN,tr|E9PGM4|E9PGM4_HUMAN" 2 1307.7449 - 35724 21784 2 1307.747028 654.8797 "1,4-alpha-glucan-branching enzyme OS=Homo sapiens OX=9606 GN=GBE1 PE=1 SV=3" 3.8 3946.9 - 1.53E+06 - - - 1.6257 - 2.131 0.362 - 210.4 1 2 0 0.0021 12 0 0 0 - - - - - 3.7048 0.999 230117_WJC_METTL3_WT_vs_EV_F04.21786.21786.2 0.000139 16-Oct R.NLPFDFTWK.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1166.576 2.79 35726 21786 2 1166.579365 584.2953 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3947.1 - 1.22E+06 - - - 2.8451 - 1.755 0.308 - 296.2 1 2 0 0.0033 9 0 0 0 1.65E+08 5.93E+07 - - - 2.9421 1 230117_WJC_METTL3_WT_vs_EV_F04.21788.21788.2 0.000578 16/28 R.VLAFLSSVAGDALTR[166.11].H sp|Q92616|GCN1_HUMAN 1 1528.8489 -1 35728 21788 2 1528.853272 765.4317 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3947.3 - 979941 - - - 2.8839 - 2.918 0.567 - 944 1 2 0 0.0044 15 0 0 0 0.00E+00 0.00E+00 - - - 5.8603 1 230117_WJC_METTL3_WT_vs_EV_F04.21789.21789.3 3.63E-06 Dec-56 R.VLAFLSSVAGDALTR.H sp|Q92616|GCN1_HUMAN 1 1518.8406 0.53 35729 21789 3 1518.844318 507.2875 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3947.4 - 926364 - - - 2.4525 - 2.559 0.539 - 219.7 1 2 0 0.0037 15 0 0 0 1.96E+06 3.73E+06 - - - 7.0001 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21791.21791.2 0.00645 20-Dec K.DFAPVIVEAFK.H "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1234.6598 2.13 35731 21791 2 1234.66287 618.3372 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.37 3947.7 - 856684 - - - 2.5068 - 2.081 0.47 - 417.7 1 2 0 0.0031 11 0 0 0 2.64E+07 1.24E+07 - - - 4.494 1 230117_WJC_METTL3_WT_vs_EV_F04.21792.21792.2 0.000102 17/26 K.LAGLVEELEADEWR.F "sp|Q96DE5|APC16_HUMAN,tr|A0A087WUN5|A0A087WUN5_HUMAN" 2 1628.8046 -1 35732 21792 2 1628.805539 815.4096 Anaphase-promoting complex subunit 16 OS=Homo sapiens OX=9606 GN=ANAPC16 PE=1 SV=1 3.91 3947.8 - 766549 - - - 0.5753 - 3.295 0.418 - 1144.2 1 2 0 0.0009 14 0 0 0 0.00E+00 0.00E+00 - - - 5.1203 0.997 230117_WJC_METTL3_WT_vs_EV_F04.21793.21793.2 0.0499 15/26 K.QIALAVLSTELAVR[166.11].K "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1492.8852 -1 35733 21793 2 1492.893619 747.4499 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3947.9 - 667696 - - - 5.6066 - 2.26 0.429 - 409.7 1 2 0 0.0084 14 0 0 0 0.00E+00 0.00E+00 - - - 4.2531 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.21794.21794.2 6.31E-05 13/24 R.NIIGVIPYFPYSK.Q "sp|Q14558|KPRA_HUMAN,tr|C9JKT9|C9JKT9_HUMAN,tr|B4DP31|B4DP31_HUMAN,tr|C9JNQ3|C9JNQ3_HUMAN,tr|C9JUN4|C9JUN4_HUMAN,tr|C9J168|C9J168_HUMAN" 6 1509.8232 -1 35734 21794 2 1509.830355 755.9189 Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Homo sapiens OX=9606 GN=PRPSAP1 PE=1 SV=2 8.5 3948.1 - 627270 - - - 4.7708 - 1.83 0.419 - 443.9 1 2 0 0.0072 13 0 0 0 0.00E+00 0.00E+00 - - - 3.6845 0.999 230117_WJC_METTL3_WT_vs_EV_F04.21796.21796.2 0.709 18-Aug R.EEIYEYIIFR.G "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 1373.6867 -1 35736 21796 2 1373.688134 687.8506 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.25 3948.3 - 514931 - - - 1.0308 - 1.623 0.278 - 185.5 1 2 0 0.0014 10 0 0 0 0.00E+00 0.00E+00 - - - 2.4456 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.21797.21797.3 0.000617 Nov-52 K.LAGLVEELEADEWR.F "sp|Q96DE5|APC16_HUMAN,tr|A0A087WUN5|A0A087WUN5_HUMAN" 2 1628.8046 -1 35737 21797 3 1628.808104 543.9421 Anaphase-promoting complex subunit 16 OS=Homo sapiens OX=9606 GN=ANAPC16 PE=1 SV=1 3.91 3948.5 - 511798 - - - 2.15 - 2.246 0.458 - 185 1 2 0 0.0035 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7956 1 230117_WJC_METTL3_WT_vs_EV_F04.21803.21803.2 9.43E-09 17/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 4.41 35742 21803 2 1591.947251 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3949 - 1.36E+07 - - - 1.4146 - 3.017 0.657 - 646.4 1 2 0 0.0023 15 0 0 0 1.33E+08 3.01E+07 - - - 6.6078 1 230117_WJC_METTL3_WT_vs_EV_F04.21804.21804.3 0.000331 14/56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 4.9 35743 21804 3 1591.947295 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3949.1 - 9.94E+06 - - - 1.4423 - 2.778 0.479 - 193.9 1 2 0 0.0023 15 0 0 0 7.15E+07 1.46E+07 - - - 6.5458 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21806.21806.2 0.00292 16-Sep R.NLPFDFTWK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1174.5902 2.79 35745 21806 2 1174.593186 588.3024 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3949.2 - 4.97E+06 - - - 2.503 - 1.629 0.363 - 209.2 1 2 0 0.0029 9 0 0 0 1.65E+08 5.93E+07 - - - 3.1329 1 230117_WJC_METTL3_WT_vs_EV_F04.21807.21807.2 6.40E-06 26-Dec K.GYAFIEFASFEDAK[136.11].E "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 10 1601.7493 0.75 35746 21807 2 1601.749113 801.8819 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.14 3949.2 - 4.20E+06 - - - -0.1324 - 2.248 0.54 - 482.8 1 2 0 -0.0002 14 0 0 0 1.30E+07 1.74E+07 - - - 5.0621 1 230117_WJC_METTL3_WT_vs_EV_F04.21808.21808.2 7.08E-08 16/24 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 1.97 35747 21808 2 1509.890674 755.9512 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3949.2 - 3.92E+06 - - - 1.8518 - 3.058 0.646 - 946.9 1 2 0 0.0028 13 0 0 0 4.29E+07 2.18E+07 - - - 6.6802 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21809.21809.2 0.000948 18-Nov R.LLELQYFISR[166.11].D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1290.7211 0.87 35748 21809 2 1290.721485 646.3678 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 6 3949.3 - 3.47E+06 - - - 0.265 - 2.264 0.401 - 579.2 1 2 0 0.0003 10 0 0 0 5.13E+06 5.91E+06 - - - 4.2835 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21810.21810.2 0.0201 18-Nov R.LLELQYFISR.D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1280.7129 -1 35749 21810 2 1280.715311 641.3637 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 6 3949.4 - 3.02E+06 - - - 1.9036 - 2.477 0.298 - 569.3 1 2 0 0.0024 10 0 0 0 0.00E+00 0.00E+00 - - - 3.7731 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21811.21811.2 2.35E-08 20-Nov K.DFAPVIVEAFK[136.11].H "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1242.674 2.15 35750 21811 2 1242.67566 622.3443 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.37 3949.4 - 2.69E+06 - - - 1.3559 - 1.991 0.438 - 359.4 1 2 0 0.0017 11 0 0 0 2.64E+07 1.23E+07 - - - 4.1385 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21812.21812.2 2.76E-05 22-Sep R.TLITFAGMIPYR.T "sp|Q8N1F7|NUP93_HUMAN,tr|H3BV15|H3BV15_HUMAN" 2 1381.7428 -1 35751 21812 2 1381.744798 691.8787 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 8.41 3949.4 - 2.59E+06 - - - 1.4511 - 2.09 0.35 - 260.7 1 2 0 0.002 12 0 0 0 0.00E+00 0.00E+00 - - - 3.5651 0.987 230117_WJC_METTL3_WT_vs_EV_F04.21816.21816.3 0.000318 Oct-52 K.LYSPSQIGAFVLMK[136.11].M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1560.8465 3.92 35755 21816 3 1560.850141 521.2895 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3949.7 - 2.29E+06 - - - 2.309 - 1.876 0.11 - 117.2 1 2 0 0.0036 14 0 0 0 2.34E+07 5.98E+06 - - - 1.4374 0.9972 230117_WJC_METTL3_WT_vs_EV_F04.21817.21817.2 0.374 14-Aug K.ISLIQIFR.A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 988.607 -1 35756 21817 2 988.611007 495.3108 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.75 3949.8 - 1.96E+06 - - - 4.1017 - 1.879 0.24 - 179.2 1 2 0 0.0041 8 0 0 0 0.00E+00 0.00E+00 - - - 2.7146 1 230117_WJC_METTL3_WT_vs_EV_F04.21818.21818.2 2.66E-07 15/32 R.AIGLSPMSFPTADLTLK.M "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1760.9383 -1 35757 21818 2 1760.942398 881.4764 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.88 3949.8 - 1.85E+06 - - - 2.351 - 2.832 0.552 - 664.9 1 2 0 0.0041 17 0 0 0 0.00E+00 0.00E+00 - - - 5.6761 0.9923 230117_WJC_METTL3_WT_vs_EV_F04.21819.21819.2 0.873 14-Jul K.ISLIQIFR[166.11].A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 998.6152 1.03 35758 21819 2 998.616894 500.3149 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.75 3949.9 - 1.81E+06 - - - 1.6743 - 1.483 0.06 - 121 1 2 0 0.0017 8 0 0 0 3.91E+06 3.78E+06 - - - 0.6721 1 230117_WJC_METTL3_WT_vs_EV_F04.21822.21822.3 4.51E-08 14/48 K.LFYADHPFIFLVR.D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1636.8766 3.28 35760 21822 3 1636.880081 546.6328 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3950.1 - 9.23E+06 - - - 2.1358 - 2.902 0.569 - 224.4 1 2 0 0.0035 13 0 0 0 4.35E+07 1.32E+07 - - - 7.7714 1 230117_WJC_METTL3_WT_vs_EV_F04.21823.21823.2 3.50E-07 14/32 R.AIGLSPMSFPTADLTLK[136.11].M "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1768.9525 -1 35761 21823 2 1768.955367 885.4835 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.88 3950.3 - 670024 - - - 1.6445 - 2.966 0.489 - 541.8 1 2 0 0.0029 17 0 0 0 0.00E+00 0.00E+00 - - - 5.3248 1 230117_WJC_METTL3_WT_vs_EV_F04.21824.21824.2 2.33E-07 13/28 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 4.41 35762 21824 2 1601.955517 801.9839 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3950.3 - 8.00E+06 - - - 1.4033 - 2.498 0.6 - 358.5 1 2 0 0.0022 15 0 0 0 1.33E+08 3.01E+07 - - - 5.7227 1 230117_WJC_METTL3_WT_vs_EV_F04.21825.21825.2 6.82E-05 24-Dec R.NVIVLQTVLQEVR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1519.8961 -1 35763 21825 2 1519.898427 760.9554 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3950.4 - 7.85E+06 - - - 1.4994 - 2.643 0.533 - 491.9 1 2 0 0.0023 13 0 0 0 0.00E+00 0.00E+00 - - - 5.4715 1 230117_WJC_METTL3_WT_vs_EV_F04.21826.21826.2 1.55E-09 14/30 L.SLGLETAGGVMTALIK.R "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1559.8593 -1 35764 21826 2 1559.860642 780.9369 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.72 3950.4 - 4.05E+06 - - - 0.8732 - 2.944 0.604 - 512.6 1 1 0 0.0014 16 0 0 0 0.00E+00 0.00E+00 - - - 6.1564 1 230117_WJC_METTL3_WT_vs_EV_F04.21829.21829.3 4.30E-06 15/48 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 -1 35767 21829 3 1509.890584 504.3032 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3950.5 - 3.01E+06 - - - 1.7922 - 2.928 0.558 - 420.1 1 2 0 0.0027 13 0 0 0 0.00E+00 0.00E+00 - - - 7.6732 1 230117_WJC_METTL3_WT_vs_EV_F04.21830.21830.2 1.09E-05 14/22 R.ILTMDGLIEDIK[136.11].H sp|P82921|RT21_HUMAN 1 1367.7462 1.34 35768 21830 2 1367.747697 684.8804 "28S ribosomal protein S21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS21 PE=1 SV=3" 4.03 3950.6 - 3.00E+06 - - - 1.1281 - 2.705 0.547 - 614.7 1 2 0 0.0015 12 0 0 0 3.98E+07 2.97E+07 - - - 5.6989 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21832.21832.2 0.00584 18-Nov K.LLELQELVLR.L "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|A0A087WYC0|A0A087WYC0_HUMAN" 3 1224.7442 -1 35770 21832 2 1224.745394 613.3794 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 4.53 3950.7 - 2.11E+06 - - - 0.9961 - 2.42 0.32 - 435.5 1 2 0 0.0012 10 0 0 0 0.00E+00 0.00E+00 - - - 3.871 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21833.21833.2 0.00115 22-Oct K.LLPLVSDEVFIR.D sp|P11216|PYGB_HUMAN 1 1399.8075 8.51 35771 21833 2 1399.808504 700.911 "Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB PE=1 SV=5" 4.37 3950.8 - 2.06E+06 - - - 0.7158 - 2.136 0.429 - 315.7 1 2 0 0.001 12 0 0 0 5.99E+06 7.04E+05 - - - 4.2062 0.9931 230117_WJC_METTL3_WT_vs_EV_F04.21834.21834.2 0.353 18-Aug K.VLLDIFTGVR.L sp|P49916|DNLI3_HUMAN 1 1131.6652 2.11 35772 21834 2 1131.666811 566.8399 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 5.81 3950.8 - 1.99E+06 - - - 1.428 - 1.593 0.072 - 141.7 2 2 0 0.0016 10 0 0 0 5.06E+06 2.40E+06 - - - 0.7375 1 230117_WJC_METTL3_WT_vs_EV_F04.21835.21835.2 1.77E-07 24-Aug K.MFVLDEADEMLSR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 11 1564.7141 -1 35773 21835 2 1564.715052 783.3643 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 3.92 3950.9 - 1.97E+06 - - - 0.6174 - 1.972 0.624 - 170.9 1 2 0 0.001 13 0 0 0 0.00E+00 0.00E+00 - - - 5.3924 1 230117_WJC_METTL3_WT_vs_EV_F04.21838.21838.2 1.40E-06 15/24 R.IGLFYMDNDLITR.N "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN" 2 1569.7861 -1 35776 21838 2 1569.793245 785.9003 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.21 3951.1 - 1.80E+06 - - - 4.542 - 3.055 0.566 - 1016.8 1 2 0 0.0071 13 0 0 0 0.00E+00 0.00E+00 - - - 6.0855 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21839.21839.2 0.000102 28-Dec R.ALVEVLGPYEPLLSR.V "sp|Q86VR2|RETR3_HUMAN,tr|K7EMF4|K7EMF4_HUMAN,tr|K7ELM8|K7ELM8_HUMAN,tr|K7EJ34|K7EJ34_HUMAN,tr|K7ENF4|K7ENF4_HUMAN,tr|K7ENZ6|K7ENZ6_HUMAN" 6 1654.9294 -1 35777 21839 2 1654.93234 828.472 Reticulophagy regulator 3 OS=Homo sapiens OX=9606 GN=RETREG3 PE=1 SV=1 4.53 3951.1 - 1.68E+06 - - - 1.7717 - 2.467 0.363 - 443.7 1 2 0 0.0029 15 0 0 0 0.00E+00 0.00E+00 - - - 3.9413 1 230117_WJC_METTL3_WT_vs_EV_F04.21840.21840.2 0.000563 15/28 K.LDLSVTEAVVAGIAK.A sp|P22102|PUR2_HUMAN 1 1484.845 -1 35778 21840 2 1484.847831 743.4298 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.37 3951.2 - 1.49E+06 - - - 1.8999 - 2.782 0.567 - 931.5 1 2 0 0.0028 15 0 0 0 0.00E+00 0.00E+00 - - - 5.7435 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21843.21843.3 0.00904 Dec-48 R.NVIVLQTVLQEVR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1519.8961 -1 35780 21843 3 1519.898231 507.6393 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3951.5 - 3.33E+06 - - - 1.3705 - 1.706 0.346 - 166.5 1 2 0 0.0021 13 0 0 0 0.00E+00 0.00E+00 - - - 3.8452 1 230117_WJC_METTL3_WT_vs_EV_F04.21845.21845.3 1.19E-08 13/48 K.LFYADHPFIFLVR[166.11].D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1646.8849 3.28 35782 21845 3 1646.88614 549.9689 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3951.6 - 5.85E+06 - - - 0.7803 - 2.867 0.619 - 188.6 1 2 0 0.0013 13 0 0 0 4.35E+07 1.32E+07 - - - 8.2966 1 230117_WJC_METTL3_WT_vs_EV_F04.21847.21847.2 7.43E-06 20-Oct K.SVFGGLVNYFK.S "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1229.6445 -1 35784 21847 2 1229.645546 615.8295 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 8.31 3951.8 - 3.63E+06 - - - 0.884 - 2.067 0.527 - 241.3 1 2 0 0.0011 11 0 0 0 0.00E+00 0.00E+00 - - - 4.8973 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.21848.21848.2 0.0123 16-Oct K.ILNIFGVIK.G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1015.643 1.55 35785 21848 2 1015.644369 508.8288 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3951.8 - 3.33E+06 - - - 1.345 - 2.05 0.239 - 240.3 1 2 0 0.0014 9 0 0 0 1.05E+07 6.74E+06 - - - 2.8826 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21849.21849.2 0.0016 16-Sep K.ILNIFGVIK[136.11].G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1023.6572 -1 35786 21849 2 1023.658015 512.8359 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3951.9 - 2.39E+06 - - - 0.7932 - 1.991 0.406 - 188.4 1 2 0 0.0008 9 0 0 0 0.00E+00 0.00E+00 - - - 4.0317 1 230117_WJC_METTL3_WT_vs_EV_F04.21850.21850.2 2.76E-08 24-Dec R.IGLFYMDNDLITR[166.11].N "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN" 2 1579.7944 -1 35787 21850 2 1579.794088 790.9045 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.21 3951.9 - 1.93E+06 - - - -0.188 - 2.659 0.59 - 566.7 1 2 0 -0.0003 13 0 0 0 0.00E+00 0.00E+00 - - - 5.9086 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.21851.21851.2 0.149 18-Sep R.ALSPLEEWLR[166.11].L "sp|P26640|SYVC_HUMAN,tr|A0A0G2JJT9|A0A0G2JJT9_HUMAN,tr|A2ABF4|A2ABF4_HUMAN,tr|A0A140T936|A0A140T936_HUMAN,tr|A0A140T954|A0A140T954_HUMAN,tr|A0A140T904|A0A140T904_HUMAN" 6 1222.6585 1.29 35788 21851 2 1222.659284 612.3365 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 4.53 3952 - 1.42E+06 - - - 0.6061 - 1.593 0.186 - 255.5 1 2 0 0.0007 10 0 0 0 5.07E+06 3.93E+06 - - - 1.7142 1 230117_WJC_METTL3_WT_vs_EV_F04.21852.21852.2 8.81E-08 18/24 K.LFYADHPFIFLVR.D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1636.8766 2.39 35789 21852 2 1636.878882 819.4456 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3952.1 - 1.34E+06 - - - 1.4033 - 2.862 0.395 - 876.5 1 2 0 0.0023 13 0 0 0 4.59E+06 1.92E+06 - - - 4.6565 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21853.21853.2 2.04E-05 22-Nov R.NMLQFNLQILPK.S "sp|O15371|EIF3D_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 3 1457.8065 -1 35790 21853 2 1457.809117 729.9105 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 8.75 3952.3 - 1.32E+06 - - - 1.8253 - 2.476 0.422 - 457.8 1 2 0 0.0027 12 0 0 0 0.00E+00 0.00E+00 - - - 4.5426 0.998 230117_WJC_METTL3_WT_vs_EV_F04.21854.21854.2 0.00179 24-Nov K.LLLQGLMDSVEAK.Q "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN" 3 1415.7694 -1 35791 21854 2 1415.770064 708.892 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 4.37 3952.4 - 1.23E+06 - - - 0.4676 - 1.483 0.244 - 196.6 1 2 0 0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 1.8544 1 230117_WJC_METTL3_WT_vs_EV_F04.21855.21855.2 9.90E-08 14/22 R.NMLQFNLQILPK[136.11].S "sp|O15371|EIF3D_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 3 1465.8207 -1 35792 21855 2 1465.822996 733.9176 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 8.75 3952.5 - 1.22E+06 - - - 1.5964 - 2.765 0.585 - 638.5 1 2 0 0.0023 12 0 0 0 0.00E+00 0.00E+00 - - - 6.0371 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21857.21857.2 0.00117 18-Sep R.ALSPLEEWLR.L "sp|P26640|SYVC_HUMAN,tr|A0A0G2JJT9|A0A0G2JJT9_HUMAN,tr|A2ABF4|A2ABF4_HUMAN,tr|A0A140T936|A0A140T936_HUMAN,tr|A0A140T954|A0A140T954_HUMAN,tr|A0A140T904|A0A140T904_HUMAN" 6 1212.6503 1.29 35794 21857 2 1212.651278 607.3324 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 4.53 3952.7 - 1.12E+06 - - - 0.8288 - 1.991 0.395 - 371.4 1 2 0 0.001 10 0 0 0 5.00E+06 3.88E+06 - - - 3.8803 1 230117_WJC_METTL3_WT_vs_EV_F04.21858.21858.2 7.94E-08 13/26 R.IVEPYVTWGFPNLK.S "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1661.8817 1.29 35795 21858 2 1661.880371 831.9481 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6 3952.8 - 1.09E+06 - - - -0.8177 - 2.467 0.586 - 508.1 1 2 0 -0.0014 14 0 0 0 3.87E+06 3.00E+06 - - - 5.6348 1 230117_WJC_METTL3_WT_vs_EV_F04.21861.21861.2 2.37E-08 14/26 R.IVEPYVTWGFPNLK[136.11].S "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1669.8959 -1 35798 21861 2 1669.898103 835.9552 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6 3953.2 - 802153 - - - 1.3013 - 2.522 0.584 - 585.3 1 2 0 0.0022 14 0 0 0 0.00E+00 0.00E+00 - - - 5.6751 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.21864.21864.2 0.00136 26-Aug R.LPLPYGFSAMQGWR.V sp|O15355|PPM1G_HUMAN 1 1621.8075 6.14 35800 21864 2 1621.813056 811.911 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 8.75 3953.5 - 512671 - - - 3.4141 - 1.571 0.376 - 123.1 1 2 0 0.0055 14 0 0 0 2.16E+06 3.52E+05 - - - 2.9499 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21867.21867.2 0.702 22-Nov K.IVILPDYLEIAR.D sp|P45974|UBP5_HUMAN 1 1413.8232 -1 35803 21867 2 1413.824791 707.9189 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 4.37 3953.8 - 2.38E+06 - - - 1.1593 - 2.125 0.391 - 315.5 1 2 0 0.0016 12 0 0 0 0.00E+00 0.00E+00 - - - 3.9117 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21868.21868.2 0.0155 24-Nov R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 35804 21868 2 1349.79322 675.9026 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3953.8 - 2.29E+06 - - - 1.9262 - 2.506 0.366 - 344.4 1 2 0 0.0026 13 0 0 0 0.00E+00 0.00E+00 - - - 4.1013 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.21869.21869.3 0.0187 Nov-40 K.ILDVEIIFNER.G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1359.7398 -1 35805 21869 3 1359.74076 454.2539 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3953.9 - 1.91E+06 - - - 0.6935 - 2.152 0.359 - 220.1 1 2 0 0.0009 11 0 0 0 0.00E+00 0.00E+00 - - - 4.7194 1 230117_WJC_METTL3_WT_vs_EV_F04.21871.21871.2 3.10E-05 13/26 K.LSPVVGAVYGPELY.A "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 7 1462.7708 - 35807 21871 2 1462.77273 732.3927 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4 3954 - 1.60E+06 - - - 1.3317 - 2.61 0.528 - 481.3 1 1 0 0.0019 14 0 0 0 - - - - - 5.3476 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21872.21872.2 0.00229 14-Sep R.TLFLELIR.A sp|Q96GM8|TOE1_HUMAN 1 1003.6066 -1 35808 21872 2 1003.607517 502.8106 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 5.66 3954.1 - 1.43E+06 - - - 0.8968 - 1.792 0.325 - 327.5 1 2 0 0.0009 8 0 0 0 0.00E+00 0.00E+00 - - - 3.2005 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.21873.21873.3 0.00106 13/40 K.ILDVEIIFNER[166.11].G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1369.7481 -1 35809 21873 3 1369.749325 457.59 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3954.2 - 1.38E+06 - - - 0.9038 - 2.157 0.355 - 319.6 1 2 0 0.0012 11 0 0 0 0.00E+00 0.00E+00 - - - 4.6814 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.21875.21875.3 2.34E-06 14/48 R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 35811 21875 3 1349.790947 450.9375 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3954.4 - 1.26E+06 - - - 0.2423 - 2.983 0.451 - 372.2 1 2 0 0.0003 13 0 0 0 0.00E+00 0.00E+00 - - - 6.5314 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.21876.21876.3 1.18E-05 13/48 R.VNILEVASGAVLR.S sp|Q12788|TBL3_HUMAN 1 1339.7823 1.38 35812 21876 3 1339.782929 447.6014 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3954.5 - 1.20E+06 - - - 0.4322 - 2.803 0.375 - 279.2 1 2 0 0.0006 13 0 0 0 2.55E+06 1.85E+06 - - - 5.5152 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.21877.21877.2 0.00503 12-Jul K.SWDIFFR.N "sp|Q02218|ODO1_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|C9J4G7|C9J4G7_HUMAN,tr|A0A0D9SFS3|A0A0D9SFS3_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 5 969.4709 -1 35813 21877 2 969.471329 485.7427 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 5.55 3954.6 - 1.07E+06 - - - 0.492 - 1.554 0.388 - 179.6 1 2 0 0.0005 7 0 0 0 0.00E+00 0.00E+00 - - - 3.3034 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21878.21878.2 2.62E-05 13/24 K.SIIGVIPYFPYSK.Q "sp|O60256|KPRB_HUMAN,tr|C9JJS3|C9JJS3_HUMAN,tr|C9JDU5|C9JDU5_HUMAN,tr|E7EPA1|E7EPA1_HUMAN,tr|E7EW35|E7EW35_HUMAN,tr|C9JDH0|C9JDH0_HUMAN,tr|C9K0K7|C9K0K7_HUMAN" 7 1482.8123 -1 35814 21878 2 1482.816016 742.4134 Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Homo sapiens OX=9606 GN=PRPSAP2 PE=1 SV=1 8.22 3954.7 - 1.05E+06 - - - 2.5377 - 2.07 0.456 - 630.7 1 2 0 0.0038 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2751 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.21879.21879.2 0.00516 12-Jul K.SWDIFFR[166.11].N "sp|Q02218|ODO1_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|C9J4G7|C9J4G7_HUMAN,tr|A0A0D9SFS3|A0A0D9SFS3_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 5 979.4791 -1 35815 21879 2 979.479602 490.7468 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 5.55 3954.8 - 1.01E+06 - - - 0.4901 - 1.409 0.385 - 173.7 1 2 0 0.0005 7 0 0 0 0.00E+00 0.00E+00 - - - 2.9709 1 230117_WJC_METTL3_WT_vs_EV_F04.21880.21880.3 1.08E-08 17/48 K.FDTPFLPKPLFFR.R sp|Q14684|RRP1B_HUMAN 1 1623.8813 -1 35816 21880 3 1623.878864 542.3011 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 8.75 3954.9 - 1.01E+06 - - - -1.5223 - 2.791 0.586 - 274.8 1 2 0 -0.0025 13 0 0 0 0.00E+00 0.00E+00 - - - 7.8555 0.9981 230117_WJC_METTL3_WT_vs_EV_F04.21882.21882.2 0.0201 20-Aug K.ATLWYVPLSLK[136.11].N "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1297.7526 0.88 35818 21882 2 1297.754707 649.8836 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 8.63 3955.1 - 905661 - - - 1.6544 - 1.353 0.259 - 171.9 1 2 0 0.0021 11 0 0 0 2.70E+06 3.05E+06 - - - 1.7712 1 230117_WJC_METTL3_WT_vs_EV_F04.21883.21883.2 4.03E-10 14/28 K.YFDTVPVAAAMC[160.03]VLK.T sp|Q15393|SF3B3_HUMAN 1 1683.8364 1.26 35819 21883 2 1683.841087 842.9255 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.83 3955.3 - 832383 - - - 2.7621 - 2.802 0.671 - 471.2 1 2 0 0.0047 15 0 0 0 3.29E+06 2.61E+06 - - - 6.5287 1 230117_WJC_METTL3_WT_vs_EV_F04.21885.21885.2 3.07E-07 24-Dec K.LGAGTFQLDQWLR[166.11].A sp|P50219|MNX1_HUMAN 1 1513.7917 -1 35820 21885 2 1513.791302 757.9031 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 5.84 3955.6 - 691510 - - - -0.2517 - 2.909 0.49 - 605 1 2 0 -0.0004 13 0 0 0 0.00E+00 0.00E+00 - - - 5.4006 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21887.21887.2 0.000454 20-Nov K.GFLSGLLDNVK.Q "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1161.6394 2.56 35822 21887 2 1161.641517 581.827 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.84 3955.7 - 3.97E+06 - - - 1.8448 - 2.247 0.353 - 357.3 1 2 0 0.0021 11 0 0 0 2.49E+07 9.73E+06 - - - 3.8377 1 230117_WJC_METTL3_WT_vs_EV_F04.21890.21890.2 0.00239 13/22 K.SLVALLVETQMK.K "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1330.753 -1 35825 21890 2 1330.755524 666.3838 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.72 3955.9 - 2.07E+06 - - - 1.8786 - 2.707 0.432 - 634.5 1 2 0 0.0025 12 0 0 0 0.00E+00 0.00E+00 - - - 4.8512 0.9941 230117_WJC_METTL3_WT_vs_EV_F04.21893.21893.2 1.64E-06 15/24 K.LAGFLDLTEQEFR[166.11].L "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 1547.7859 2.19 35828 21893 2 1547.796311 774.9002 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.14 3956.1 - 1.32E+06 - - - 6.7076 - 2.621 0.388 - 1075.1 1 2 0 0.0104 13 0 0 0 3.48E+07 1.59E+07 - - - 4.3765 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21894.21894.2 0.0099 20-Oct K.FVSISDLLVPK.D sp|P50395|GDIB_HUMAN 1 1216.7067 -1 35829 21894 2 1216.709776 609.3606 Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2 5.84 3956.1 - 1.28E+06 - - - 2.5076 - 1.693 0.469 - 219.8 1 2 0 0.0031 11 0 0 0 0.00E+00 0.00E+00 - - - 3.9284 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.21895.21895.2 0.117 16-Jul R.LFIFETFC[160.03]R[166.11].L "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 12 1241.6142 7.01 35830 21895 2 1241.616905 621.8144 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 5.99 3956.2 - 1.25E+06 - - - 2.1496 - 1.458 0.361 - 171.1 1 2 0 0.0027 9 0 0 0 3.11E+07 4.44E+06 - - - 2.7974 0.9961 230117_WJC_METTL3_WT_vs_EV_F04.21897.21897.2 0.4 16-Jul R.DLGFFGIYK[136.11].G sp|Q9UJS0|CMC2_HUMAN 1 1066.5579 -1 35832 21897 2 1066.561065 534.2862 Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13 PE=1 SV=2 5.83 3956.4 - 736958 - - - 2.9834 - 1.118 0.31 - 80.2 1 2 0 0.0032 9 0 0 0 0.00E+00 0.00E+00 - - - 1.6524 1 230117_WJC_METTL3_WT_vs_EV_F04.21898.21898.2 0.000426 14/26 K.LDDIFEPVLIPEPK.L "sp|Q14008|CKAP5_HUMAN,tr|H0YEK7|H0YEK7_HUMAN,tr|H0YCF6|H0YCF6_HUMAN" 3 1623.876 -1 35833 21898 2 1623.878497 812.9453 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 3.92 3956.5 - 726492 - - - 1.5525 - 2.564 0.521 - 573.8 1 2 0 0.0025 14 0 0 0 0.00E+00 0.00E+00 - - - 5.2511 1 230117_WJC_METTL3_WT_vs_EV_F04.21900.21900.3 2.70E-08 14/52 K.LLPVLVHTFWIDTK.N sp|Q13505|MTX1_HUMAN 1 1680.9603 -1 35835 21900 3 1680.964967 561.3274 Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1 PE=1 SV=3 6.74 3956.7 - 658873 - - - 2.7681 - 2.668 0.595 - 254.5 1 2 0 0.0047 14 0 0 0 0.00E+00 0.00E+00 - - - 7.7803 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.21907.21907.2 0.000163 20-Dec K.ILDVEIIFNER.G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1359.7398 1.48 35841 21907 2 1359.74247 680.8772 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3957.5 - 512677 - - - 1.9511 - 2.061 0.378 - 396.3 1 2 0 0.0027 11 0 0 0 4.18E+07 2.83E+07 - - - 3.7885 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21909.21909.2 0.00635 20-Oct K.LILPELGPVFK[136.11].Q "sp|Q6P3W7|SCYL2_HUMAN,tr|H0YIK6|H0YIK6_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 1232.7624 0.6 35843 21909 2 1232.763978 617.3885 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6 3957.6 - 8.14E+06 - - - 1.2833 - 1.929 0.465 - 330.5 1 2 0 0.0016 11 0 0 0 2.13E+07 3.53E+07 - - - 4.2523 0.8986 230117_WJC_METTL3_WT_vs_EV_F04.21913.21913.2 7.16 20-Jun R.VTWEPAPGEVK.G "sp|Q99715|COCA1_HUMAN,tr|D6RGG3|D6RGG3_HUMAN" 2 1211.6186 2079.68 35847 21913 2 1211.617595 606.8166 Collagen alpha-1(XII) chain OS=Homo sapiens OX=9606 GN=COL12A1 PE=1 SV=2 4.53 3957.8 - 3.32E+06 - - - -0.8617 - 1.225 0.016 - 129.5 3 2 0 -0.001 11 0 0 0 3.63E+08 1.75E+05 - - - -0.5053 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.21914.21914.2 0.000137 20-Dec K.NLVELAELELK.H "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN" 2 1269.718 -1 35848 21914 2 1269.719974 635.8663 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 4.25 3957.8 - 3.01E+06 - - - 1.5405 - 2.256 0.248 - 456.7 1 2 0 0.002 11 0 0 0 0.00E+00 0.00E+00 - - - 3.0731 1 230117_WJC_METTL3_WT_vs_EV_F04.21915.21915.3 0.00119 18/60 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 -1 35849 21915 3 1663.954577 555.6576 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3957.9 - 2.91E+06 - - - 2.2266 - 3.392 0.464 - 350.1 1 2 0 0.0037 16 0 0 0 0.00E+00 0.00E+00 - - - 6.8461 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.21916.21916.2 0.391 20-Sep K.DVLLPWYNAYR.F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1408.7139 -1 35850 21916 2 1408.718186 705.3642 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3958 - 2.55E+06 - - - 3.0169 - 2.001 0.337 - 218.3 1 2 0 0.0043 11 0 0 0 0.00E+00 0.00E+00 - - - 3.4052 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.21918.21918.3 0.000652 14/48 R.IESILMSLPLTAR.W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1442.8167 1.42 35852 21918 3 1442.818643 481.9462 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3958.1 - 2.10E+06 - - - 1.3557 - 2.651 0.437 - 267.8 1 2 0 0.002 13 0 0 0 5.92E+06 4.18E+06 - - - 6.0549 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.21919.21919.3 1.47E-06 13/48 R.IESILMSLPLTAR[166.11].W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1452.825 -1 35853 21919 3 1452.825808 485.2823 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3958.1 - 1.98E+06 - - - 0.5858 - 2.794 0.393 - 235.1 1 2 0 0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 5.7071 1 230117_WJC_METTL3_WT_vs_EV_F04.21920.21920.2 2.08E-05 13/22 R.ANLGVFSVFAPR[166.11].G "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1286.7011 1.06 35854 21920 2 1286.699849 644.3578 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 9.79 3958.2 - 1.86E+06 - - - -0.9544 - 2.526 0.48 - 558.8 1 2 0 -0.0012 12 0 0 0 6.00E+06 5.65E+06 - - - 5.024 1 230117_WJC_METTL3_WT_vs_EV_F04.21922.21922.2 5.50E-10 17/30 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 -1 35856 21922 2 1663.954434 832.9827 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3958.4 - 1.70E+06 - - - 2.1407 - 3.474 0.513 - 895.7 1 2 0 0.0036 16 0 0 0 0.00E+00 0.00E+00 - - - 5.8905 1 230117_WJC_METTL3_WT_vs_EV_F04.21923.21923.2 2.62E-11 20/30 K.INEAIVAVQAIIADPK[136.11].T sp|Q9Y224|RTRAF_HUMAN 1 1671.9651 -1 35857 21923 2 1671.965989 836.9898 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3958.5 - 1.29E+06 - - - 0.5485 - 3.556 0.559 - 1299.4 1 2 0 0.0009 16 0 0 0 0.00E+00 0.00E+00 - - - 6.2885 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.21924.21924.2 4.71E-05 20-Dec K.DVLLPWYNAYR[166.11].F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1418.7222 1.53 35858 21924 2 1418.726795 710.3684 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3958.6 - 1.27E+06 - - - 3.2346 - 2.143 0.46 - 518 1 2 0 0.0046 11 0 0 0 1.19E+07 7.78E+06 - - - 4.4991 1 230117_WJC_METTL3_WT_vs_EV_F04.21927.21927.3 2.72E-08 14/60 K.INEAIVAVQAIIADPK[136.11].T sp|Q9Y224|RTRAF_HUMAN 1 1671.9651 -1 35860 21927 3 1671.967888 558.329 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3958.9 - 2.24E+06 - - - 1.6842 - 2.565 0.517 - 172.1 1 2 0 0.0028 16 0 0 0 0.00E+00 0.00E+00 - - - 6.7202 1 230117_WJC_METTL3_WT_vs_EV_F04.21929.21929.2 1.47E-11 18/34 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 -1 35862 21929 2 1911.947329 956.9806 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3959.1 - 2.75E+07 - - - 0.3944 - 3.733 0.635 - 1140.8 1 2 0 0.0008 18 0 0 0 0.00E+00 0.00E+00 - - - 6.9693 1 230117_WJC_METTL3_WT_vs_EV_F04.21930.21930.2 2.87E-10 15/26 K.VVIGMDVAASEFFR.S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1539.7756 1.75 35863 21930 2 1539.775105 770.8951 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.37 3959.1 - 1.25E+07 - - - -0.289 - 2.997 0.683 - 788.9 1 2 0 -0.0004 14 0 0 0 2.87E+07 1.64E+07 - - - 6.8399 1 230117_WJC_METTL3_WT_vs_EV_F04.21933.21933.2 3.62E-06 13/18 K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 999 35866 21933 2 1146.629434 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3959.2 - 6.87E+06 - - - 0.8364 - 2.351 0.521 - 484 1 2 0 0.001 10 0 0 0 7.49E+07 0.00E+00 - - - 5.2749 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.21934.21934.3 1.90E-06 14/68 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 -1 35867 21934 3 1911.944875 638.3228 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3959.3 - 6.39E+06 - - - -0.8891 - 2.421 0.447 - 190.5 1 2 0 -0.0017 18 0 0 0 0.00E+00 0.00E+00 - - - 5.7248 1 230117_WJC_METTL3_WT_vs_EV_F04.21937.21937.2 1.09E-05 22-Nov K.GVNSYPSLFIFR.S "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0TB22|A0A7P0TB22_HUMAN,tr|A0A7P0Z4F2|A0A7P0Z4F2_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN,tr|E7EP04|E7EP04_HUMAN,tr|A0A7P0T9B7|A0A7P0T9B7_HUMAN,tr|A0A494C1G5|A0A494C1G5_HUMAN,tr|A0A7P0TB83|A0A7P0TB83_HUMAN" 10 1398.7296 -1 35870 21937 2 1398.731325 700.3721 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 8.75 3959.4 - 4.60E+06 - - - 1.2433 - 2.423 0.531 - 265.3 1 2 0 0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 5.291 1 230117_WJC_METTL3_WT_vs_EV_F04.21938.21938.2 5.34E-09 20/34 K.LGGSLADSYLDEGFLLDK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1919.9608 -1 35871 21938 2 1919.960029 960.9877 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3959.5 - 3.92E+06 - - - -0.3885 - 3.913 0.663 - 1756.8 1 2 0 -0.0007 18 0 0 0 0.00E+00 0.00E+00 - - - 7.2919 1 230117_WJC_METTL3_WT_vs_EV_F04.21941.21941.3 2.95E-07 Dec-52 K.VVIGMDVAASEFFR.S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1539.7756 -1 35874 21941 3 1539.777923 514.2658 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.37 3959.7 - 2.29E+06 - - - 1.5411 - 2.769 0.581 - 206.3 1 2 0 0.0024 14 0 0 0 0.00E+00 0.00E+00 - - - 7.7236 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.21948.21948.2 0.00145 22-Nov K.WGDIEFPPPFGR[166.11].E sp|P53396|ACLY_HUMAN 1 1426.6909 2.1 35880 21948 2 1426.692469 714.3527 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.37 3960.5 - 1.30E+06 - - - 1.0955 - 1.869 0.446 - 355.3 1 2 0 0.0016 12 0 0 0 8.69E+06 4.14E+06 - - - 3.9802 1 230117_WJC_METTL3_WT_vs_EV_F04.21950.21950.2 4.50E-07 20-Dec K.VMVQPINLIFR.Y sp|P62304|RUXE_HUMAN 1 1328.7639 -1 35882 21950 2 1328.763071 665.3892 Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1 9.72 3960.7 - 4.27E+07 - - - -0.596 - 2.578 0.582 - 446.4 1 2 0 -0.0008 11 0 0 0 0.00E+00 0.00E+00 - - - 5.9013 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.21953.21953.2 0.00632 16-Sep R.C[160.03]LLAYFLDK.S "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1141.5842 -1 35885 21953 2 1141.583465 571.7994 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 5.83 3960.8 - 4.55E+06 - - - -0.6158 - 1.842 0.377 - 253 1 2 0 -0.0007 9 0 0 0 0.00E+00 0.00E+00 - - - 3.5925 1 230117_WJC_METTL3_WT_vs_EV_F04.21962.21962.2 2.00E-08 16/26 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.27 35892 21962 2 1676.898338 839.4565 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3961.6 - 2.55E+07 - - - -0.0978 - 3.392 0.575 - 959.2 1 2 0 -0.0002 14 0 0 0 9.23E+07 7.26E+07 - - - 6.353 1 230117_WJC_METTL3_WT_vs_EV_F04.21963.21963.2 7.16E-05 26-Nov M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 1.27 35893 21963 2 1686.906912 844.4607 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3961.6 - 2.06E+07 - - - 0.083 - 2.663 0.545 - 317.8 1 2 0 0.0001 14 0 0 0 9.23E+07 7.26E+07 - - - 5.5242 1 230117_WJC_METTL3_WT_vs_EV_F04.21967.21967.3 1.30E-08 16/52 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.36 35897 21967 3 1676.898789 559.9734 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3961.8 - 8.37E+06 - - - 0.1711 - 3.164 0.586 - 320.4 1 2 0 0.0003 14 0 0 0 2.59E+07 1.90E+07 - - - 8.1343 1 230117_WJC_METTL3_WT_vs_EV_F04.21968.21968.3 9.99E-08 15/52 M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 1.36 35898 21968 3 1686.907033 563.3095 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3961.9 - 6.83E+06 - - - 0.1547 - 2.686 0.524 - 265.9 1 2 0 0.0003 14 0 0 0 2.59E+07 1.90E+07 - - - 7.0078 1 230117_WJC_METTL3_WT_vs_EV_F04.21969.21969.2 2.58E-07 13/22 K.LIC[160.03]C[160.03]DILDVLDK.H "sp|P62258|1433E_HUMAN,tr|K7EIT4|K7EIT4_HUMAN" 2 1475.7364 -1 35899 21969 2 1475.735601 738.8755 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 3.93 3961.9 - 6.56E+06 - - - -0.5333 - 2.599 0.665 - 512.7 1 2 0 -0.0008 12 0 0 0 0.00E+00 0.00E+00 - - - 6.4655 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.21970.21970.2 0.000179 26-Dec K.VPGLPTPIENMILR.Y "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1548.8698 -1 35900 21970 2 1548.868779 775.4422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3962 - 5.88E+06 - - - -0.6495 - 2.268 0.416 - 321 1 2 0 -0.001 14 0 0 0 0.00E+00 0.00E+00 - - - 4.1682 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.21972.21972.2 9.51E-05 15/24 R.ALTLGALTLPLAR.L sp|Q9BSJ8|ESYT1_HUMAN 1 1308.8129 -1 35902 21972 2 1308.811446 655.4137 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 9.79 3962.1 - 3.91E+06 - - - -1.1277 - 2.741 0.387 - 900.1 1 2 0 -0.0015 13 0 0 0 0.00E+00 0.00E+00 - - - 4.4868 1 230117_WJC_METTL3_WT_vs_EV_F04.21974.21974.2 9.63E-05 14/24 R.ALTLGALTLPLAR[166.11].L sp|Q9BSJ8|ESYT1_HUMAN 1 1318.8212 -1 35904 21974 2 1318.819202 660.4179 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 9.79 3962.2 - 3.74E+06 - - - -1.5089 - 2.283 0.498 - 582.2 1 2 0 -0.002 13 0 0 0 0.00E+00 0.00E+00 - - - 4.8372 1 230117_WJC_METTL3_WT_vs_EV_F04.21975.21975.2 1.24E-06 16/26 K.MQLMELAILNGTYR.D "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1651.8426 2.5 35905 21975 2 1651.842779 826.9286 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 5.75 3962.4 - 3.10E+06 - - - 0.118 - 2.915 0.602 - 787.9 1 2 0 0.0002 14 0 0 0 1.17E+07 4.66E+06 - - - 6.1721 0.9988 230117_WJC_METTL3_WT_vs_EV_F04.21976.21976.2 0.0566 16-Dec K.AGLVELLLR.E "sp|Q13425|SNTB2_HUMAN,tr|A0A140TA73|A0A140TA73_HUMAN" 2 982.6175 -1 35906 21976 2 982.61581 492.316 Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1 6.05 3962.5 - 2.09E+06 - - - -1.7362 - 2.443 0.364 - 482.8 1 2 0 -0.0017 9 0 0 0 0.00E+00 0.00E+00 - - - 4.3131 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.21978.21978.2 0.00717 26-Nov R.VGVDPLIIPTDYWK.K "sp|Q9NQW7|XPP1_HUMAN,tr|Q5T6H2|Q5T6H2_HUMAN,tr|Q5T6H3|Q5T6H3_HUMAN,tr|Q5T6H7|Q5T6H7_HUMAN" 4 1614.8657 -1 35908 21978 2 1614.86942 808.4401 Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3 4.21 3962.7 - 2.00E+06 - - - 2.2757 - 1.578 0.34 - 200.5 1 2 0 0.0037 14 0 0 0 0.00E+00 0.00E+00 - - - 2.6958 1 230117_WJC_METTL3_WT_vs_EV_F04.21984.21984.2 3.20E-06 20-Nov K.TFSFAIPLIEK[136.11].L sp|Q9NR30|DDX21_HUMAN 1 1272.7209 0.96 35913 21984 2 1272.720121 637.3677 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.66 3963.3 - 3.55E+07 - - - -0.6317 - 2.073 0.584 - 299.3 1 2 0 -0.0008 11 0 0 0 7.86E+07 8.23E+07 - - - 5.3263 1 230117_WJC_METTL3_WT_vs_EV_F04.21985.21985.2 3.36E-05 20-Oct K.TFSFAIPLIEK.L sp|Q9NR30|DDX21_HUMAN 1 1264.7067 0.96 35914 21985 2 1264.706144 633.3606 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.66 3963.4 - 3.44E+07 - - - -0.4594 - 1.963 0.526 - 204.8 1 2 0 -0.0006 11 0 0 0 7.86E+07 8.23E+07 - - - 4.7505 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.21986.21986.2 0.00971 16-Sep R.FLILPDMLK.N sp|P62318|SMD3_HUMAN 1 1088.6304 -1 35915 21986 2 1088.630087 545.3225 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.84 3963.4 - 2.23E+07 - - - -0.2774 - 1.749 0.425 - 253.1 1 2 0 -0.0003 9 0 0 0 0.00E+00 0.00E+00 - - - 3.7973 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.21987.21987.2 0.00565 16-Aug R.FLILPDMLK[136.11].N sp|P62318|SMD3_HUMAN 1 1096.6446 -1 35916 21987 2 1096.644518 549.3296 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.84 3963.5 - 2.01E+07 - - - -0.0647 - 1.593 0.382 - 169.5 1 2 0 -0.0001 9 0 0 0 0.00E+00 0.00E+00 - - - 3.2095 1 230117_WJC_METTL3_WT_vs_EV_F04.21988.21988.2 2.30E-05 20-Nov K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 999 35917 21988 2 1106.546273 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3963.5 - 9.03E+06 - - - -0.1166 - 2.232 0.485 - 322.3 1 2 0 -0.0001 11 0 0 0 2.17E+07 0.00E+00 - - - 4.7952 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.21995.21995.2 0.00145 20-Aug K.LVPDLLAIVQR.K "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1235.7602 1.25 35924 21995 2 1235.762984 618.8874 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.84 3963.9 - 2.54E+06 - - - 2.2869 - 1.592 0.326 - 209.7 1 2 0 0.0028 11 0 0 0 7.73E+06 6.19E+06 - - - 2.7059 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.21997.21997.2 0.092 28-Oct R.LGLEFFDQPAVPLAR[166.11].A "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1681.9067 -1 35926 21997 2 1681.906263 841.9606 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 4.37 3964.1 - 2.38E+06 - - - -0.267 - 1.637 0.255 - 142.7 1 2 0 -0.0004 15 0 0 0 0.00E+00 0.00E+00 - - - 2.136 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.21999.21999.2 0.0408 14-Oct R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 38.78 35928 21999 2 1000.557922 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3964.2 - 2.09E+06 - - - -1.4102 - 2.129 0.285 - 350.3 1 2 0 -0.0014 8 0 0 0 1.22E+07 3.13E+05 - - - 3.4246 0.9692 230117_WJC_METTL3_WT_vs_EV_F04.22003.22003.2 0.382 20-Oct K.VNLLSVLEAAK[136.11].M sp|Q9BRX8|PXL2A_HUMAN 1 1163.7005 -1 35931 22003 2 1163.698831 582.8575 Peroxiredoxin-like 2A OS=Homo sapiens OX=9606 GN=PRXL2A PE=1 SV=3 5.97 3964.6 - 887675 - - - -1.4548 - 1.255 0.124 - 161.8 1 2 0 -0.0017 11 0 0 0 0.00E+00 0.00E+00 - - - 0.5708 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.22004.22004.2 2.93E-06 16/28 R.YLSIIEGLDASDPLR.V "sp|Q9Y5J3|HEY1_HUMAN,tr|E5RHK6|E5RHK6_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 5 1660.8672 3.81 35932 22004 2 1660.866757 831.4409 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 4.03 3964.8 - 1.38E+06 - - - -0.2679 - 2.527 0.4 - 696.8 1 2 0 -0.0004 15 0 0 0 5.55E+06 1.46E+06 - - - 4.2744 1 230117_WJC_METTL3_WT_vs_EV_F04.22007.22007.2 0.000131 13/22 R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 -1 35935 22007 2 1301.707708 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3964.9 - 7.39E+06 - - - -0.1076 - 2.671 0.55 - 424.8 1 2 0 -0.0001 12 0 0 0 0.00E+00 0.00E+00 - - - 5.6883 1 230117_WJC_METTL3_WT_vs_EV_F04.22012.22012.2 0.000912 13/20 K.LVLADLLEPVK.T sp|Q9BVJ6|UT14A_HUMAN 1 1208.738 1.59 35940 22012 2 1208.74387 605.3763 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3965.2 - 1.99E+06 - - - 4.8348 - 2.366 0.576 - 457.4 1 2 0 0.0058 11 0 0 0 2.09E+07 1.31E+07 - - - 5.6233 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.22013.22013.2 0.00101 24-Dec R.DPQLVPILIEAAR.N "sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 2 1433.8242 -1 35941 22013 2 1433.827492 717.9194 "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=NSDHL PE=1 SV=2" 4.37 3965.3 - 1.93E+06 - - - 2.2855 - 2.257 0.468 - 368.9 1 2 0 0.0033 13 0 0 0 0.00E+00 0.00E+00 - - - 4.5859 1 230117_WJC_METTL3_WT_vs_EV_F04.22016.22016.2 7.33E-11 18/34 K.LLGTIYTAAEEIEAVGGK.A sp|Q6YN16|HSDL2_HUMAN 1 1833.9724 -1 35944 22016 2 1833.972386 917.9935 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3965.7 - 1.44E+06 - - - -0.0049 - 3.698 0.654 - 1150.1 1 2 0 0 18 0 0 0 0.00E+00 0.00E+00 - - - 7.0867 0.9976 230117_WJC_METTL3_WT_vs_EV_F04.22017.22017.2 0.00123 20-Sep K.LVLADLLEPVK[136.11].T sp|Q9BVJ6|UT14A_HUMAN 1 1216.7522 1.59 35945 22017 2 1216.749824 609.3834 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3965.8 - 1.36E+06 - - - -1.9741 - 1.895 0.339 - 216.6 1 2 0 -0.0024 11 0 0 0 2.09E+07 1.31E+07 - - - 3.2733 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.22020.22020.2 3.25E-05 14-Oct R.C[160.03]FLSWLVK.L sp|Q92900|RENT1_HUMAN 1 1051.5525 -1 35948 22020 2 1051.555001 526.7835 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.22 3966.2 - 1.20E+06 - - - 2.4031 - 1.962 0.422 - 427.3 1 2 0 0.0025 8 0 0 0 0.00E+00 0.00E+00 - - - 4.1897 0.9932 230117_WJC_METTL3_WT_vs_EV_F04.22021.22021.2 0.0467 16-Aug K.LELPLWLAK.G sp|Q9BRX5|PSF3_HUMAN 1 1081.6536 -1 35949 22021 2 1081.653547 541.8341 DNA replication complex GINS protein PSF3 OS=Homo sapiens OX=9606 GN=GINS3 PE=1 SV=1 6 3966.3 - 1.14E+06 - - - -0.0194 - 1.441 0.128 - 158.1 1 2 0 0 9 0 0 0 0.00E+00 0.00E+00 - - - 1.0433 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.22029.22029.3 0.0701 18/44 K.C[160.03]LVFSLIGLHFK[136.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1440.8043 0.79 35956 22029 3 1440.804267 481.2754 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3967.1 - 6.00E+06 - - - -0.0076 - 2.724 0.412 - 502.9 1 2 0 0 12 0 0 0 9.92E+06 1.26E+07 - - - 5.9111 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.22030.22030.3 1.34E-05 19/44 K.C[160.03]LVFSLIGLHFK.L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1432.7901 0.79 35957 22030 3 1432.789463 478.604 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3967.2 - 4.07E+06 - - - -0.4292 - 2.776 0.454 - 637.7 1 2 0 -0.0006 12 0 0 0 9.92E+06 1.26E+07 - - - 6.4316 0.9818 230117_WJC_METTL3_WT_vs_EV_F04.22034.22034.2 0.537 12-Jul K.DVLDSVL.- sp|P81605|DCD_HUMAN 1 759.4014 - 35961 22034 2 759.400922 380.708 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.56 3967.5 - 1.65E+06 - - - -0.6755 - 1.135 0.157 - 167.6 1 2 0 -0.0005 7 0 0 0 - - - - - 0.6017 1 230117_WJC_METTL3_WT_vs_EV_F04.22037.22037.2 3.33E-06 13/22 K.QFEELTLGEFLK.L "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1452.75 -1 35964 22037 2 1452.754717 727.3823 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.25 3967.9 - 1.24E+06 - - - 3.2146 - 2.407 0.441 - 748.9 1 2 0 0.0047 12 0 0 0 0.00E+00 0.00E+00 - - - 4.6079 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.22041.22041.3 0.00156 Dec-56 K.NLAEALLTYETLDAK.E sp|Q96TA2|YMEL1_HUMAN 1 1663.8669 -1 35968 22041 3 1663.866502 555.6296 ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX=9606 GN=YME1L1 PE=1 SV=2 4.14 3968.4 - 1.09E+06 - - - -0.22 - 2.377 0.393 - 191.5 1 2 0 -0.0004 15 0 0 0 0.00E+00 0.00E+00 - - - 5.1808 0.998 230117_WJC_METTL3_WT_vs_EV_F04.22043.22043.2 0.00953 22-Aug K.QFEELTLGEFLK[136.11].L "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1460.7642 -1 35970 22043 2 1460.768664 731.3894 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.25 3968.7 - 1.02E+06 - - - 3.0238 - 1.777 0.241 - 144 1 2 0 0.0044 12 0 0 0 0.00E+00 0.00E+00 - - - 2.3324 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.22045.22045.2 0.00209 18-Aug K.GGFDWNLVFK.W sp|Q10471|GALT2_HUMAN 1 1181.5869 -1 35971 22045 2 1181.587877 591.8007 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.84 3968.9 - 1.42E+06 - - - 0.7888 - 1.477 0.408 - 122.7 1 2 0 0.0009 10 0 0 0 0.00E+00 0.00E+00 - - - 3.1428 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.22048.22048.2 0.00552 18-Nov K.STLLLLLTGK[136.11].L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1065.6889 -1 35974 22048 2 1065.689892 533.8517 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3969.1 - 2.34E+06 - - - 0.9337 - 2.245 0.435 - 431.6 1 2 0 0.001 10 0 0 0 0.00E+00 0.00E+00 - - - 4.5109 1 230117_WJC_METTL3_WT_vs_EV_F04.22054.22054.2 9.40E-07 22-Dec K.GDLDLELVLLC[160.03]K[136.11].E "sp|Q12906|ILF3_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 1394.7571 -1 35980 22054 2 1394.759357 698.3858 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.03 3969.6 - 1.46E+06 - - - 1.6519 - 2.635 0.544 - 597.4 1 2 0 0.0023 12 0 0 0 0.00E+00 0.00E+00 - - - 5.6076 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.22057.22057.2 0.071 24-Sep K.IPLKPPPLELLNV.- sp|O15504|NUP42_HUMAN 1 1441.8908 1.61 35983 22057 2 1441.892913 721.9527 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 3969.8 - 995118 - - - 1.4391 - 1.73 0.282 - 245.7 1 2 0 0.0021 13 0 0 0 6.12E+06 3.81E+06 - - - 2.53 0.9952 230117_WJC_METTL3_WT_vs_EV_F04.22059.22059.2 0.158 16-Jul K.SGNYFFLDD.- sp|P61221|ABCE1_HUMAN 1 1076.4451 - 35985 22059 2 1076.446601 539.2298 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 3.89 3970 - 735689 - - - 1.4028 - 1.139 0.215 - 96.6 1 2 0 0.0015 9 0 0 0 - - - - - 1.005 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.22062.22062.2 0.033 24-Aug K.IPLK[136.11]PPPLELLNV.- sp|O15504|NUP42_HUMAN 1 1449.905 1.61 35988 22062 2 1449.904758 725.9598 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 3970.4 - 596277 - - - -0.1931 - 1.664 0.393 - 208.5 1 2 0 -0.0003 13 0 0 0 6.12E+06 3.81E+06 - - - 3.2505 1 230117_WJC_METTL3_WT_vs_EV_F04.22063.22063.2 1.75E-08 13/22 R.LGDPLEAFPVFK.K "sp|Q86UY6|NAA40_HUMAN,tr|F5H2C9|F5H2C9_HUMAN" 2 1331.7125 1.41 35989 22063 2 1331.717603 666.8635 N-alpha-acetyltransferase 40 OS=Homo sapiens OX=9606 GN=NAA40 PE=1 SV=1 4.37 3970.6 - 490235 - - - 3.8026 - 2.862 0.567 - 747 1 2 0 0.0051 12 0 0 0 9.25E+06 6.57E+06 - - - 5.994 1 230117_WJC_METTL3_WT_vs_EV_F04.22068.22068.2 1.72E-05 18-Dec K.STLLLLLTGK.L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1057.6747 -1 35993 22068 2 1057.676054 529.8446 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3971.2 - 4.24E+06 - - - 1.283 - 2.323 0.538 - 496.3 1 2 0 0.0014 10 0 0 0 0.00E+00 0.00E+00 - - - 5.3669 0.9954 230117_WJC_METTL3_WT_vs_EV_F04.22069.22069.2 0.00199 14-Aug R.GFGFILFK[136.11].D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 935.536 0.85 35994 22069 2 935.535105 468.7753 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3971.3 - 3.87E+06 - - - -0.9834 - 1.557 0.199 - 176.6 1 2 0 -0.0009 8 0 0 0 4.21E+07 4.95E+07 - - - 1.8459 0.9963 230117_WJC_METTL3_WT_vs_EV_F04.22070.22070.2 0.368 14-Aug K.GSLLDFLK.E "sp|P07947|YES_HUMAN,sp|P09769|FGR_HUMAN,sp|P07948|LYN_HUMAN,sp|P08631|HCK_HUMAN,sp|P06241|FYN_HUMAN,sp|P12931|SRC_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|J3QRU1|J3QRU1_HUMAN" 9 891.5066 -1 35995 22070 2 891.506942 446.7606 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 3971.4 - 2.81E+06 - - - 0.4184 - 1.49 0.151 - 222.5 1 2 0 0.0004 8 0 0 0 0.00E+00 0.00E+00 - - - 1.3589 1 230117_WJC_METTL3_WT_vs_EV_F04.22073.22073.2 1.52E-05 15/24 R.LLSLISIALPENK.V "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1409.8494 -1 35998 22073 2 1409.851229 705.932 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 6 3971.6 - 1.98E+06 - - - 1.3207 - 2.807 0.537 - 735 1 2 0 0.0019 13 0 0 0 0.00E+00 0.00E+00 - - - 5.6557 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.22074.22074.2 0.0312 16-Sep R.VNILFDFVK.K sp|P55010|IF5_HUMAN 1 1093.6172 -1 35999 22074 2 1093.618928 547.8159 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.81 3971.6 - 1.88E+06 - - - 1.5965 - 1.99 0.368 - 278 1 2 0 0.0017 9 0 0 0 0.00E+00 0.00E+00 - - - 3.7493 1 230117_WJC_METTL3_WT_vs_EV_F04.22075.22075.2 4.54E-05 18-Nov K.ILYDILAFAK[136.11].E "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1173.6889 -1 36000 22075 2 1173.692047 587.8517 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.83 3971.7 - 1.84E+06 - - - 2.6838 - 2.343 0.434 - 266.9 1 2 0 0.0032 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6221 1 230117_WJC_METTL3_WT_vs_EV_F04.22076.22076.2 9.28E-06 18-Nov K.ILYDILAFAK.E "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1165.6747 -1 36001 22076 2 1165.677176 583.8446 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.83 3971.8 - 1.78E+06 - - - 2.1267 - 2.27 0.521 - 300.1 1 2 0 0.0025 10 0 0 0 0.00E+00 0.00E+00 - - - 5.1766 1 230117_WJC_METTL3_WT_vs_EV_F04.22078.22078.2 2.24E-06 20-Dec R.LWGLTEMFPER.V sp|Q9NS69|TOM22_HUMAN 1 1377.6751 1.49 36003 22078 2 1377.676561 689.8448 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 4.53 3972 - 1.37E+06 - - - 1.0547 - 2.334 0.522 - 513.3 1 2 0 0.0015 11 0 0 0 7.46E+06 5.01E+06 - - - 5.1889 0.9973 230117_WJC_METTL3_WT_vs_EV_F04.22079.22079.2 0.0212 14-Jul R.GFGFILFK.D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 927.5218 0.85 36004 22079 2 927.522209 464.7682 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3972.1 - 1.36E+06 - - - 0.414 - 1.371 0.22 - 140.3 1 2 0 0.0004 8 0 0 0 4.21E+07 4.95E+07 - - - 1.6175 1 230117_WJC_METTL3_WT_vs_EV_F04.22080.22080.2 2.07E-06 15/22 R.LGDPLEAFPVFK[136.11].K "sp|Q86UY6|NAA40_HUMAN,tr|F5H2C9|F5H2C9_HUMAN" 2 1339.7267 1.41 36005 22080 2 1339.727689 670.8706 N-alpha-acetyltransferase 40 OS=Homo sapiens OX=9606 GN=NAA40 PE=1 SV=1 4.37 3972.2 - 1.10E+06 - - - 0.7091 - 2.871 0.575 - 826.4 1 2 0 0.0009 12 0 0 0 9.25E+06 6.57E+06 - - - 6.0626 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.22081.22081.2 2.54E-05 13/22 R.LAQNILSYLDLK.S sp|Q9UL15|BAG5_HUMAN 1 1389.7868 -1 36006 22081 2 1389.791875 695.9007 BAG family molecular chaperone regulator 5 OS=Homo sapiens OX=9606 GN=BAG5 PE=1 SV=1 5.83 3972.2 - 1.07E+06 - - - 3.6754 - 2.177 0.469 - 622 1 2 0 0.0051 12 0 0 0 0.00E+00 0.00E+00 - - - 4.5503 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.22082.22082.2 0.283 14-Aug K.GSLLDFLK[136.11].E "sp|P07947|YES_HUMAN,sp|P09769|FGR_HUMAN,sp|P07948|LYN_HUMAN,sp|P08631|HCK_HUMAN,sp|P06241|FYN_HUMAN,sp|P12931|SRC_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|J3QRU1|J3QRU1_HUMAN" 9 899.5208 -1 36007 22082 2 899.521014 450.7677 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 3972.4 - 1.06E+06 - - - 0.2724 - 1.649 0.143 - 179.3 1 2 0 0.0002 8 0 0 0 0.00E+00 0.00E+00 - - - 1.6056 1 230117_WJC_METTL3_WT_vs_EV_F04.22083.22083.2 2.04E-06 13/24 R.VSELQVLLGYAGR.N "sp|O75925|PIAS1_HUMAN,tr|H3BSI8|H3BSI8_HUMAN" 2 1403.7773 -1 36008 22083 2 1403.778734 702.8959 E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=9606 GN=PIAS1 PE=1 SV=2 5.97 3972.5 - 792477 - - - 1.0465 - 2.572 0.496 - 531.5 1 2 0 0.0015 13 0 0 0 0.00E+00 0.00E+00 - - - 5.1286 1 230117_WJC_METTL3_WT_vs_EV_F04.22090.22090.3 2.79E-08 27/80 N.WITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 2344.2539 7.65 36014 22090 3 2344.25731 782.4253 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3973.2 - 4.47E+06 - - - 1.4418 - 4.128 0.589 - 616.7 1 1 0 0.0034 21 0 0 0 2.43E+07 3.18E+06 - - - 8.5049 1 230117_WJC_METTL3_WT_vs_EV_F04.22093.22093.2 3.58E-05 18-Oct R.DFVVGALILR.S sp|Q9NUD5|ZCHC3_HUMAN 1 1101.6546 -1 36017 22093 2 1101.656729 551.8346 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 5.84 3973.4 - 2.49E+06 - - - 1.9053 - 2.028 0.524 - 342.1 1 2 0 0.0021 10 0 0 0 0.00E+00 0.00E+00 - - - 4.8842 1 230117_WJC_METTL3_WT_vs_EV_F04.22094.22094.3 2.12E-05 17/52 K.FLTLPPVLHLQLMR.F "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1676.98 2.68 36018 22094 3 1676.982268 560.0006 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 9.76 3973.5 - 2.08E+06 - - - 1.35 - 2.838 0.518 - 382.1 1 2 0 0.0023 14 0 0 0 6.58E+06 2.46E+06 - - - 7.0866 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.22097.22097.2 1.52E-05 20-Nov R.LWGLTEMFPER[166.11].V sp|Q9NS69|TOM22_HUMAN 1 1387.6834 1.63 36021 22097 2 1387.684753 694.849 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 4.53 3973.8 - 1.91E+06 - - - 0.9909 - 2.283 0.414 - 499.6 1 2 0 0.0014 11 0 0 0 9.47E+06 5.80E+06 - - - 4.3315 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.22098.22098.2 1.43E-05 18-Aug R.DFVVGALILR[166.11].S sp|Q9NUD5|ZCHC3_HUMAN 1 1111.6629 1.22 36022 22098 2 1111.664228 556.8387 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 5.84 3973.9 - 1.84E+06 - - - 1.1946 - 1.917 0.502 - 266.2 1 2 0 0.0013 10 0 0 0 4.55E+06 3.72E+06 - - - 4.5648 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.22099.22099.3 0.00274 13/52 K.FLTLPPVLHLQLMR[166.11].F "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1686.9883 -1 36023 22099 3 1686.989277 563.3367 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 9.76 3974 - 1.57E+06 - - - 0.5946 - 2.7 0.389 - 175.2 1 2 0 0.001 14 0 0 0 0.00E+00 0.00E+00 - - - 5.5163 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.22100.22100.2 0.00774 16-Jul K.EVWDYVFFK[136.11].E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PRP1|A0A6I8PRP1_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 1239.6056 -1 36024 22100 2 1239.606691 620.8101 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.37 3974.1 - 1.47E+06 - - - 0.9116 - 1.681 0.42 - 180.2 1 2 0 0.0011 9 0 0 0 0.00E+00 0.00E+00 - - - 3.6454 0.8572 230117_WJC_METTL3_WT_vs_EV_F04.22104.22104.2 0.00165 26-Jul K.IFFIDPNERPVTLY.H "sp|O95619|YETS4_HUMAN,tr|F8W1B9|F8W1B9_HUMAN,tr|F8VTR4|F8VTR4_HUMAN" 3 1722.8981 -1 36028 22104 2 1722.899481 862.4563 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 4.37 3974.6 - 1.01E+06 - - - 0.7969 - 1.467 0.235 - 77.9 1 1 0 0.0014 14 0 0 0 0.00E+00 0.00E+00 - - - 1.7379 1 230117_WJC_METTL3_WT_vs_EV_F04.22105.22105.2 0.00117 20-Nov R.YFGELLADLSR.K sp|Q8WVV4|POF1B_HUMAN 1 1282.6558 -1 36029 22105 2 1282.655002 642.3352 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 4.37 3974.7 - 895278 - - - -0.5847 - 2.022 0.576 - 349.7 1 2 0 -0.0008 11 0 0 0 0.00E+00 0.00E+00 - - - 5.1998 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.22108.22108.2 0.0127 22-Oct K.IIDEDGLLNLIR.T "sp|P35251|RFC1_HUMAN,tr|H0Y8U4|H0Y8U4_HUMAN" 2 1382.7769 1.5 36031 22108 2 1382.779855 692.3957 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 4.03 3975.1 - 1.23E+06 - - - 2.1153 - 2.034 0.326 - 225.8 1 2 0 0.0029 12 0 0 0 4.71E+06 3.13E+06 - - - 3.3161 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.22109.22109.2 0.000214 26-Dec R.GLLEESSFATLFPK.Y sp|Q13601|KRR1_HUMAN 1 1537.8028 0.97 36032 22109 2 1537.802157 769.9087 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3975.2 - 1.24E+06 - - - -0.4253 - 2.194 0.419 - 481.8 1 2 0 -0.0007 14 0 0 0 8.70E+06 8.93E+06 - - - 4.1073 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.22112.22112.3 5.53E-05 19/56 R.TVFRPPLDIYDVLIR.L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0C4DFX0|A0A0C4DFX0_HUMAN" 2 1816.0247 0.98 36035 22112 3 1816.02405 606.3488 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.63 3975.4 - 2.05E+06 - - - -0.3612 - 2.793 0.544 - 402.7 1 2 0 -0.0007 15 0 0 0 8.84E+06 9.04E+06 - - - 7.285 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.22115.22115.2 1.26 18-Dec R.ILGLLDAYLK[136.11].T sp|P26641|EF1G_HUMAN 1 1125.6889 0.86 36038 22115 2 1125.690803 563.8517 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3975.6 - 1.34E+06 - - - 1.6932 - 2.525 0.312 - 339.4 1 2 0 0.0019 10 0 0 0 5.86E+07 6.82E+07 - - - 3.9303 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.22117.22117.2 0.00296 14-Aug R.SIFLFLDR.T "sp|Q13619|CUL4A_HUMAN,sp|Q13620|CUL4B_HUMAN,tr|A0A7P0Z4G9|A0A7P0Z4G9_HUMAN,tr|A0A7P0T8P8|A0A7P0T8P8_HUMAN,tr|A0A7P0T9D0|A0A7P0T9D0_HUMAN,tr|A0A669KAX4|A0A669KAX4_HUMAN,tr|A0A0A0MR50|A0A0A0MR50_HUMAN,tr|K4DI93|K4DI93_HUMAN,tr|A0A804CL36|A0A804CL36_HUMAN,tr|A0A7P0T9C8|A0A7P0T9C8_HUMAN,tr|A0A7P0T954|A0A7P0T954_HUMAN,tr|A0A087WWN2|A0A087WWN2_HUMAN,tr|A0A7P0T9P5|A0A7P0T9P5_HUMAN,tr|A0A669KBG9|A0A669KBG9_HUMAN,tr|A0A7P0T9R8|A0A7P0T9R8_HUMAN,tr|A0A7P0TAF9|A0A7P0TAF9_HUMAN,tr|A0A7P0T9L3|A0A7P0T9L3_HUMAN,tr|A0A7P0TAQ3|A0A7P0TAQ3_HUMAN" 18 1009.5597 -1 36040 22117 2 1009.561635 505.7871 Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV=3 5.55 3975.8 - 1.16E+06 - - - 1.9494 - 1.694 0.301 - 255 1 2 0 0.002 8 0 0 0 0.00E+00 0.00E+00 - - - 2.8533 1 230117_WJC_METTL3_WT_vs_EV_F04.22119.22119.2 5.39E-07 24-Dec R.ENFFLGGVTLPLK.D sp|O00443|P3C2A_HUMAN 1 1433.7919 1.12 36042 22119 2 1433.791514 717.9032 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 6.1 3976.1 - 471936 - - - -0.2357 - 2.274 0.562 - 372.3 1 2 0 -0.0003 13 0 0 0 2.10E+06 1.88E+06 - - - 5.3003 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.22126.22126.2 0.000821 18-Oct R.ILGLLDAYLK.T sp|P26641|EF1G_HUMAN 1 1117.6747 0.86 36047 22126 2 1117.677275 559.8446 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3977 - 1.80E+07 - - - 2.3066 - 2.205 0.33 - 239 1 2 0 0.0026 10 0 0 0 5.86E+07 6.82E+07 - - - 3.6847 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.22129.22129.2 0.994 18-Oct K.NIFAILQSVK[136.11].A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1139.6794 -1 36050 22129 2 1139.680848 570.847 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3977.1 - 2.90E+06 - - - 1.2749 - 2.077 0.31 - 233 1 2 0 0.0015 10 0 0 0 0.00E+00 0.00E+00 - - - 3.3704 1 230117_WJC_METTL3_WT_vs_EV_F04.22131.22131.3 2.23E-08 16/72 R.MPAEIVVLLDSEDNPSLPK[136.11].R sp|Q9BUA3|SPNDC_HUMAN 1 2074.0748 -1 36052 22131 3 2074.07618 692.3655 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 3.92 3977.2 - 2.16E+06 - - - 0.6851 - 2.865 0.549 - 255.2 1 2 0 0.0014 19 0 0 0 0.00E+00 0.00E+00 - - - 7.2464 1 230117_WJC_METTL3_WT_vs_EV_F04.22133.22133.2 0.122 19/28 R.IPGLLSPHPLLQLSY.T "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1646.9396 - 36054 22133 2 1646.941311 824.4771 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.74 3977.4 - 1.57E+06 - - - 1.0516 - 3.278 0.495 - 1192.6 1 1 0 0.0017 15 0 0 0 - - - - - 5.6154 1 230117_WJC_METTL3_WT_vs_EV_F04.22134.22134.3 9.21E-06 15/60 R.IPAEVLILNSIVLPHK.E "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 2 1755.0658 2.31 36055 22134 3 1755.067316 586.0292 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 6.75 3977.5 - 1.39E+06 - - - 0.8399 - 2.817 0.553 - 318.5 1 2 0 0.0015 16 0 0 0 5.26E+06 2.28E+06 - - - 7.3624 1 230117_WJC_METTL3_WT_vs_EV_F04.22137.22137.2 0.000929 26-Oct R.GLLEESSFATLFPK[136.11].Y sp|Q13601|KRR1_HUMAN 1 1545.817 0.97 36058 22137 2 1545.815972 773.9158 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3977.7 - 1.26E+06 - - - -0.6721 - 2.517 0.563 - 317.6 1 2 0 -0.001 14 0 0 0 8.70E+06 8.93E+06 - - - 5.5154 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.22140.22140.3 0.000338 Oct-72 R.MPAEIVVLLDSEDNPSLPK.R sp|Q9BUA3|SPNDC_HUMAN 1 2066.0606 -1 36061 22140 3 2066.060454 689.6941 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 3.92 3978 - 1.06E+06 - - - -0.0508 - 1.972 0.353 - 96.1 1 2 0 -0.0001 19 0 0 0 0.00E+00 0.00E+00 - - - 4.1439 0.9963 230117_WJC_METTL3_WT_vs_EV_F04.22141.22141.2 0.0524 20-Aug R.YIFTMLSSLAR[166.11].L sp|P11388|TOP2A_HUMAN 1 1310.6932 -1 36062 22141 2 1310.695981 656.3539 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 8.75 3978.1 - 876513 - - - 2.1111 - 1.634 0.148 - 160.4 2 2 0 0.0028 11 0 0 0 0.00E+00 0.00E+00 - - - 1.3271 1 230117_WJC_METTL3_WT_vs_EV_F04.22142.22142.2 6.63E-05 15/24 K.NPILWNVADVVIK.F "sp|P04844|RPN2_HUMAN,tr|H0Y5M1|H0Y5M1_HUMAN,tr|Q5JYR3|Q5JYR3_HUMAN" 3 1479.8449 -1 36063 22142 2 1479.845717 740.9298 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 5.84 3978.2 - 785959 - - - 0.5183 - 2.83 0.543 - 431.8 1 2 0 0.0008 13 0 0 0 0.00E+00 0.00E+00 - - - 5.7213 0.9978 230117_WJC_METTL3_WT_vs_EV_F04.22143.22143.3 4.89E-06 17/44 K.LR[166.11]EC[160.03]LPLIIFLR[166.11].N sp|P62701|RS4X_HUMAN 1 1561.9281 0.88 36064 22143 3 1561.929909 521.65 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3978.3 - 696375 - - - 1.139 - 3.144 0.517 - 576 1 2 1 0.0018 12 0 0 0 3.92E+07 4.46E+07 - - - 7.4787 1 230117_WJC_METTL3_WT_vs_EV_F04.22145.22145.3 6.99E-10 18/44 K.LREC[160.03]LPLIIFLR.N sp|P62701|RS4X_HUMAN 1 1541.9116 0.88 36066 22145 3 1541.909992 514.9778 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3978.6 - 621092 - - - -1.0364 - 3.355 0.586 - 713.1 1 2 1 -0.0016 12 0 0 0 3.92E+07 4.46E+07 - - - 8.4281 1 230117_WJC_METTL3_WT_vs_EV_F04.22147.22147.2 1.82E-07 13/26 K.LLSDFLDSEVSELR[166.11].T sp|Q9BPX3|CND3_HUMAN 1 1631.8282 -1 36067 22147 2 1631.82874 816.9214 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 3.92 3978.8 - 439575 - - - 0.3389 - 2.571 0.556 - 490.6 1 2 0 0.0006 14 0 0 0 0.00E+00 0.00E+00 - - - 5.5171 1 230117_WJC_METTL3_WT_vs_EV_F04.22152.22152.2 2.27E-06 13/22 K.VNFLPEIITLSK.E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1372.7966 1.02 36072 22152 2 1372.799011 687.4056 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.97 3979.1 - 2.01E+06 - - - 1.7541 - 2.215 0.543 - 499.5 1 2 0 0.0024 12 0 0 0 7.66E+06 7.53E+06 - - - 5.1433 1 230117_WJC_METTL3_WT_vs_EV_F04.22153.22153.2 2.09E-06 22-Nov K.VNFLPEIITLSK[136.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1380.8108 0.92 36073 22153 2 1380.81182 691.4127 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.97 3979.2 - 1.83E+06 - - - 0.7365 - 2.13 0.531 - 338.2 1 2 0 0.001 12 0 0 0 7.66E+06 8.31E+06 - - - 4.9521 1 230117_WJC_METTL3_WT_vs_EV_F04.22154.22154.2 4.27E-10 14/24 R.SDFFLEGPFMPPR.M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1538.7228 2.41 36074 22154 2 1538.723768 770.3687 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3979.3 - 1.36E+06 - - - 0.6382 - 2.736 0.532 - 670.2 1 2 0 0.001 13 0 0 0 1.03E+07 4.28E+06 - - - 5.5532 1 230117_WJC_METTL3_WT_vs_EV_F04.22156.22156.2 0.00196 24-Nov R.GNSIIMLEALERV.- "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1443.7756 -1 36076 22156 2 1443.778052 722.8951 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3979.5 - 935902 - - - 1.733 - 2.516 0.437 - 428.7 1 2 0 0.0025 13 0 0 0 0.00E+00 0.00E+00 - - - 4.636 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.22158.22158.2 0.0523 13/22 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 1.01 36078 22158 2 1336.848753 669.4314 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3979.7 - 756403 - - - 0.38 - 2.441 0.363 - 579.3 1 2 0 0.0005 12 0 0 0 1.17E+08 1.15E+08 - - - 4.07 0.9749 230117_WJC_METTL3_WT_vs_EV_F04.22159.22159.2 0.00237 14-Aug R.EC[160.03]LNLWGY.E sp|Q86U44|MTA70_HUMAN 1 1053.459 - 36079 22159 2 1053.460216 527.7368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3979.9 - 745925 - - - 1.1856 - 1.653 0.461 - 247.5 1 1 0 0.0012 8 0 0 0 - - - - - 3.9613 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.22160.22160.2 0.0284 14/22 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 1.01 36080 22160 2 1344.864759 673.4385 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3980 - 672182 - - - 1.7206 - 2.472 0.368 - 685.8 1 2 0 0.0023 12 0 0 0 1.17E+08 1.15E+08 - - - 4.1396 0.9979 230117_WJC_METTL3_WT_vs_EV_F04.22162.22162.2 0.0004 22-Nov R.SFLALDWDPDLK[136.11].K sp|Q9Y4E8|UBP15_HUMAN 1 1426.7224 7.07 36082 22162 2 1426.726938 714.3685 Ubiquitin carboxyl-terminal hydrolase 15 OS=Homo sapiens OX=9606 GN=USP15 PE=1 SV=3 3.93 3980.2 - 472942 - - - 3.1933 - 2.391 0.141 - 439.5 1 2 0 0.0046 12 0 0 0 1.69E+07 2.40E+06 - - - 2.3746 0.9702 230117_WJC_METTL3_WT_vs_EV_F04.22163.22163.2 0.865 24-Jun R.EYMSPDIALLYLK.H sp|Q7RTY7|OVCH1_HUMAN 1 1554.8004 4.34 36083 22163 2 1554.804149 778.4075 Ovochymase-1 OS=Homo sapiens OX=9606 GN=OVCH1 PE=2 SV=2 4.37 3980.4 - 460480 - - - 2.4318 - 1.167 0.066 - 69.3 1 2 0 0.0038 13 0 0 0 4.17E+06 9.60E+05 - - - -0.0763 1 230117_WJC_METTL3_WT_vs_EV_F04.22168.22168.2 2.80E-05 13/22 R.LGPLLDILADSR.H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1281.7293 1.7 36087 22168 2 1281.731203 641.8719 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3981 - 1.00E+07 - - - 1.5222 - 2.587 0.499 - 633.8 1 2 0 0.002 12 0 0 0 2.96E+07 1.74E+07 - - - 5.2269 1 230117_WJC_METTL3_WT_vs_EV_F04.22169.22169.2 1.08E-10 17/30 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 2.66 36088 22169 2 1751.867216 876.9399 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3981.1 - 8.70E+06 - - - 1.1776 - 3.308 0.689 - 777.8 1 2 0 0.0021 16 0 0 0 2.72E+07 1.02E+07 - - - 7.0706 1 230117_WJC_METTL3_WT_vs_EV_F04.22170.22170.2 2.24E-06 16/22 R.LGPLLDILADSR[166.11].H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1291.7375 1.7 36089 22170 2 1291.739724 646.876 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3981.1 - 6.12E+06 - - - 1.7047 - 2.983 0.523 - 1116.9 1 2 0 0.0022 12 0 0 0 2.96E+07 1.74E+07 - - - 5.7789 1 230117_WJC_METTL3_WT_vs_EV_F04.22171.22171.3 1.03E-10 16/60 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 2.67 36090 22171 3 1751.867871 584.9623 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3981.2 - 4.83E+06 - - - 1.5515 - 3.157 0.617 - 510.4 1 2 0 0.0027 16 0 0 0 1.32E+07 4.93E+06 - - - 8.368 1 230117_WJC_METTL3_WT_vs_EV_F04.22172.22172.2 4.62E-09 18/30 K.VGEVTYVELLMDAEGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1759.8794 -1 36091 22172 2 1759.881154 880.947 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3981.2 - 3.75E+06 - - - 1.0234 - 3.589 0.632 - 786.9 1 2 0 0.0018 16 0 0 0 0.00E+00 0.00E+00 - - - 6.8501 1 230117_WJC_METTL3_WT_vs_EV_F04.22175.22175.2 4.82E-08 15/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 4.87 36094 22175 2 1591.945681 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3981.4 - 2.54E+06 - - - 0.4284 - 2.776 0.586 - 506.3 1 2 0 0.0007 15 0 0 0 4.25E+07 8.73E+06 - - - 5.8792 1 230117_WJC_METTL3_WT_vs_EV_F04.22176.22176.3 1.08E-09 15/60 K.VGEVTYVELLMDAEGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1759.8794 -1 36095 22176 3 1759.879589 587.6337 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3981.5 - 2.18E+06 - - - 0.1341 - 3.036 0.591 - 375 1 2 0 0.0002 16 0 0 0 0.00E+00 0.00E+00 - - - 7.9785 1 230117_WJC_METTL3_WT_vs_EV_F04.22177.22177.2 9.75E-06 24-Nov R.GNSIIMLEALER[166.11]V.- "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1453.7838 -1 36096 22177 2 1453.787284 727.8992 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3981.5 - 2.01E+06 - - - 2.3827 - 2.412 0.454 - 497.8 1 2 0 0.0035 13 0 0 0 0.00E+00 0.00E+00 - - - 4.6529 0.9525 230117_WJC_METTL3_WT_vs_EV_F04.22178.22178.2 0.359 20-Aug R.LLDMDGIIVEK.Q sp|Q14152|EIF3A_HUMAN 1 1244.6686 2.79 36097 22178 2 1244.665625 623.3416 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.03 3981.6 - 1.81E+06 - - - -2.4103 - 1.394 0.101 - 124 1 2 0 -0.003 11 0 0 0 4.06E+06 1.45E+06 - - - 0.6847 0.8568 230117_WJC_METTL3_WT_vs_EV_F04.22179.22179.2 0.0233 12-May K.TSFFQAL.G "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 9 812.4069 - 36098 22179 2 812.407101 407.2107 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 5.19 3981.7 - 1.45E+06 - - - 0.3028 - 1.128 0.334 - 100.9 1 1 0 0.0002 7 0 0 0 - - - - - 1.8895 0.9972 230117_WJC_METTL3_WT_vs_EV_F04.22181.22181.2 0.00535 18-Jun K.GGPGLPLPPL.- sp|Q9H7N4|SFR19_HUMAN 1 916.5382 - 36100 22181 2 916.539241 459.2764 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.52 3981.9 - 1.32E+06 - - - 1.1325 - 1.248 0.241 - 121.5 1 2 0 0.001 10 0 0 0 - - - - - 1.4391 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.22182.22182.2 0.0181 20-Dec K.LGELPSWILMR[166.11].D "sp|P56134|ATPK_HUMAN,tr|G3V325|G3V325_HUMAN,tr|C9JU26|C9JU26_HUMAN,tr|C9JJT5|C9JJT5_HUMAN" 4 1323.7248 1.16 36101 22182 2 1323.728336 662.8697 "ATP synthase subunit f, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MF PE=1 SV=3" 6 3982 - 1.23E+06 - - - 2.6342 - 2.215 0.428 - 382.6 1 2 0 0.0035 11 0 0 0 4.34E+06 3.75E+06 - - - 4.3525 0.9923 230117_WJC_METTL3_WT_vs_EV_F04.22184.22184.2 0.144 16-Aug R.QLYLPMLFK.V "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN" 13 1151.6413 -1 36103 22184 2 1151.642323 576.8279 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3982.1 - 1.22E+06 - - - 0.8987 - 1.266 0.13 - 118.5 1 2 0 0.001 9 0 0 0 0.00E+00 0.00E+00 - - - 0.6832 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.22185.22185.3 0.00244 Nov-56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 4.97 36104 22185 3 1591.947283 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3982.2 - 1.20E+06 - - - 1.4347 - 2.069 0.406 - 137.5 1 2 0 0.0023 15 0 0 0 2.27E+07 4.56E+06 - - - 4.963 1 230117_WJC_METTL3_WT_vs_EV_F04.22186.22186.2 1.19E-05 22-Dec K.LR[166.11]EC[160.03]LPLIIFLR[166.11].N sp|P62701|RS4X_HUMAN 1 1561.9281 -1 36105 22186 2 1561.928908 781.9713 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3982.3 - 1.01E+06 - - - 0.4981 - 2.539 0.495 - 137.2 1 2 1 0.0008 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1485 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.22187.22187.2 0.0815 20-Aug R.FLIPVLNGLEK[136.11].K "sp|Q92797|SYMPK_HUMAN,tr|A0A087WUE9|A0A087WUE9_HUMAN" 2 1249.7526 -1 36106 22187 2 1249.755675 625.8836 Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2 6 3982.4 - 931258 - - - 2.4925 - 1.487 0.24 - 164.9 1 2 0 0.0031 11 0 0 0 0.00E+00 0.00E+00 - - - 1.886 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.22192.22192.2 0.000247 18-Oct K.VLVYELLLGK.G sp|Q96P11|NSUN5_HUMAN 1 1145.706 -1 36110 22192 2 1145.70781 573.8603 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 5.97 3982.8 - 1.65E+06 - - - 1.5824 - 1.929 0.435 - 290.9 1 2 0 0.0018 10 0 0 0 0.00E+00 0.00E+00 - - - 4.0872 1 230117_WJC_METTL3_WT_vs_EV_F04.22193.22193.2 3.54E-07 13/20 K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 1.02 36111 22193 2 1315.788177 658.9005 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3982.9 - 1.35E+06 - - - 1.371 - 2.294 0.543 - 628.5 1 2 0 0.0018 11 0 0 0 1.38E+07 1.35E+07 - - - 5.2972 0.998 230117_WJC_METTL3_WT_vs_EV_F04.22194.22194.2 0.000713 18-Sep K.VLVYELLLGK[136.11].G sp|Q96P11|NSUN5_HUMAN 1 1153.7202 -1 36112 22194 2 1153.725232 577.8674 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 5.97 3983 - 1.32E+06 - - - 4.3641 - 1.678 0.391 - 165.7 1 2 0 0.005 10 0 0 0 0.00E+00 0.00E+00 - - - 3.3721 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.22195.22195.3 0.00176 14/44 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 0.97 36113 22195 3 1336.849462 446.6234 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3983.1 - 1.29E+06 - - - 0.9104 - 2.364 0.471 - 278.4 1 2 0 0.0012 12 0 0 0 8.12E+06 8.36E+06 - - - 6.1756 1 230117_WJC_METTL3_WT_vs_EV_F04.22196.22196.3 9.34E-05 16/44 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 0.97 36114 22196 3 1344.863283 449.2948 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3983.1 - 1.26E+06 - - - 0.6231 - 2.563 0.506 - 349.3 1 2 0 0.0008 12 0 0 0 8.12E+06 8.36E+06 - - - 6.79 1 230117_WJC_METTL3_WT_vs_EV_F04.22198.22198.2 0.000127 20-Nov K.EYPFILDAFQR[166.11].E sp|P42285|MTREX_HUMAN 1 1407.7062 1.11 36116 22198 2 1407.709603 704.8604 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 3983.3 - 1.08E+06 - - - 2.4018 - 2.149 0.516 - 526.2 1 2 0 0.0034 11 0 0 0 5.47E+06 4.91E+06 - - - 4.9206 1 230117_WJC_METTL3_WT_vs_EV_F04.22200.22200.2 2.16E-06 13/24 K.GIVSEEAYILFVR.K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1494.8082 0.6 36118 22200 2 1494.81022 748.4114 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.53 3983.5 - 1.02E+06 - - - 1.3313 - 2.581 0.484 - 755.6 1 2 0 0.002 13 0 0 0 5.74E+06 9.62E+06 - - - 5.0487 1 230117_WJC_METTL3_WT_vs_EV_F04.22202.22202.2 1.90E-06 26-Dec R.LLQSPC[160.03]PFC[160.03]DSPVF.- sp|Q9UKN8|TF3C4_HUMAN 1 1665.7531 - 36120 22202 2 1665.758241 833.8838 General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2 3.8 3983.8 - 667662 - - - 3.0857 - 2.117 0.597 - 300.9 1 2 0 0.0051 14 0 0 0 - - - - - 5.3309 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.22203.22203.2 3.76E-07 24-Nov R.SDFFLEGPFMPPR[166.11].M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1548.7311 2.41 36121 22203 2 1548.734004 775.3728 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3983.9 - 526945 - - - 1.9035 - 2.3 0.445 - 263.3 1 2 0 0.0029 13 0 0 0 1.03E+07 4.28E+06 - - - 4.4645 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.22204.22204.3 9.54E-07 14/48 K.GIVSEEAYILFVR.K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1494.8082 1.53 36122 22204 3 1494.80829 499.2767 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.53 3984 - 474570 - - - 0.0401 - 2.576 0.479 - 226 1 2 0 0.0001 13 0 0 0 3.66E+06 2.38E+06 - - - 6.4459 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.22210.22210.3 0.00353 13/40 K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 -1 36127 22210 3 1315.785952 439.6027 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3984.8 - 880088 - - - -0.32 - 2.6 0.421 - 322.9 1 2 0 -0.0004 11 0 0 0 0.00E+00 0.00E+00 - - - 5.9481 1 230117_WJC_METTL3_WT_vs_EV_F04.22212.22212.3 7.43E-08 18/52 R.LLNNAFEELVAFQR.A "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1662.873 -1 36129 22212 3 1662.873981 555.2983 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.53 3985 - 3.25E+06 - - - 0.6164 - 2.702 0.617 - 380.8 1 2 0 0.001 14 0 0 0 0.00E+00 0.00E+00 - - - 8.0602 1 230117_WJC_METTL3_WT_vs_EV_F04.22213.22213.2 1.06E-06 15/28 K.LGLLGLANSLAIEGR.K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1495.8722 -1 36130 22213 2 1495.874384 748.9434 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3985 - 2.99E+06 - - - 1.4413 - 3.044 0.596 - 906.4 1 2 0 0.0022 15 0 0 0 0.00E+00 0.00E+00 - - - 6.1792 1 230117_WJC_METTL3_WT_vs_EV_F04.22217.22217.2 2.89E-05 13/28 K.LGLLGLANSLAIEGR[166.11].K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1505.8805 -1 36134 22217 2 1505.882383 753.9475 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3985.3 - 1.48E+06 - - - 1.2518 - 2.856 0.573 - 609 1 2 0 0.0019 15 0 0 0 0.00E+00 0.00E+00 - - - 5.8526 1 230117_WJC_METTL3_WT_vs_EV_F04.22218.22218.3 4.62E-07 15/60 R.FLLPEYLPYAGIFHER.G "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1964.0196 -1 36135 22218 3 1964.024074 655.6805 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 5.4 3985.4 - 1.36E+06 - - - 2.2678 - 2.676 0.523 - 186.3 1 2 0 0.0045 16 0 0 0 0.00E+00 0.00E+00 - - - 6.8953 1 230117_WJC_METTL3_WT_vs_EV_F04.22219.22219.2 2.83E-05 26-Oct K.ELAEEGVLEEAEFY.N sp|Q14681|KCTD2_HUMAN 1 1626.7301 - 36136 22219 2 1626.730834 814.3723 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 3.46 3985.5 - 1.07E+06 - - - 0.4518 - 2.155 0.553 - 160 1 1 0 0.0007 14 0 0 0 - - - - - 5.052 0.9772 230117_WJC_METTL3_WT_vs_EV_F04.22220.22220.2 7.55E-05 20-Nov R.ALGQLFHIAC[160.03]F.T "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9JJK5|C9JJK5_HUMAN" 3 1275.6434 - 36137 22220 2 1275.645384 638.829 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 6.78 3985.6 - 1.02E+06 - - - 1.5443 - 2.021 0.439 - 254.7 1 1 0 0.002 11 0 0 0 - - - - - 4.1862 1 230117_WJC_METTL3_WT_vs_EV_F04.22224.22224.2 1.75E-09 13/24 K.APDEETLIALLAH.A "sp|Q9Y3E5|PTH2_HUMAN,tr|J3KQ48|J3KQ48_HUMAN" 2 1391.7296 - 36141 22224 2 1391.733111 696.8721 "Peptidyl-tRNA hydrolase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PTRH2 PE=1 SV=1" 4.13 3986.1 - 509060 - - - 2.4897 - 2.75 0.583 - 454.8 1 1 0 0.0035 13 0 0 0 - - - - - 5.9423 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.22229.22229.2 7.95E-06 30-Dec R.VPLSPLSLLAGPADAR.R "sp|Q53ET0|CRTC2_HUMAN,tr|Q5T4K5|Q5T4K5_HUMAN,tr|H0YDQ8|H0YDQ8_HUMAN" 3 1575.8984 -1 36146 22229 2 1575.899136 788.9565 CREB-regulated transcription coactivator 2 OS=Homo sapiens OX=9606 GN=CRTC2 PE=1 SV=2 5.81 3986.8 - 385496 - - - 0.4404 - 1.93 0.506 - 260.5 1 2 0 0.0007 16 0 0 0 0.00E+00 0.00E+00 - - - 4.3946 0.938 230117_WJC_METTL3_WT_vs_EV_F04.22234.22234.2 0.00737 18-Aug E.QEEDISSLIR.S sp|P78527|PRKDC_HUMAN 1 1188.5986 -1 36150 22234 2 1188.598922 595.3066 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.14 3987.3 - 5.06E+06 - - - 0.244 - 1.529 0.362 - 176.4 1 1 0 0.0003 10 0 0 0 0.00E+00 0.00E+00 - - - 2.8999 1 230117_WJC_METTL3_WT_vs_EV_F04.22235.22235.2 7.49E-06 14/22 R.NLQNLLILTAIK[136.11].A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1360.8533 1.01 36151 22235 2 1360.852886 681.4339 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3987.3 - 4.21E+06 - - - -0.3314 - 2.491 0.499 - 582.1 1 2 0 -0.0004 12 0 0 0 3.85E+07 3.82E+07 - - - 5.1279 1 230117_WJC_METTL3_WT_vs_EV_F04.22236.22236.2 7.53E-05 16/28 R.LPFLSSSNLSLDVLR.G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1659.9196 -1 36152 22236 2 1660.924745 830.9671 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3987.4 - 3.73E+06 - - - 605.5552 - 3.137 0.522 - 904.3 1 2 0 1.0052 15 0 0 0 0.00E+00 0.00E+00 - - - 5.3916 1 230117_WJC_METTL3_WT_vs_EV_F04.22237.22237.2 0.000607 13/18 K.LNMILVQILK.Q "sp|O14980|XPO1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 1183.7363 -1 36153 22237 2 1183.737895 592.8754 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3987.4 - 3.33E+06 - - - 1.3888 - 2.643 0.456 - 693.8 1 2 0 0.0016 10 0 0 0 0.00E+00 0.00E+00 - - - 5.1214 1 230117_WJC_METTL3_WT_vs_EV_F04.22238.22238.2 2.45E-05 22-Dec R.NLQNLLILTAIK.A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1352.8391 -1 36154 22238 2 1352.836114 677.4268 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3987.5 - 3.22E+06 - - - -2.2346 - 2.483 0.567 - 470.4 1 2 0 -0.003 12 0 0 0 0.00E+00 0.00E+00 - - - 5.6209 1 230117_WJC_METTL3_WT_vs_EV_F04.22239.22239.2 6.25E-08 18/28 R.LPFLSSSNLSLDVLR[166.11].G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1669.9278 -1 36155 22239 2 1669.928287 835.9712 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3987.5 - 3.15E+06 - - - 0.2665 - 3.399 0.638 - 1019.8 1 2 0 0.0004 15 0 0 0 0.00E+00 0.00E+00 - - - 6.7611 1 230117_WJC_METTL3_WT_vs_EV_F04.22240.22240.2 3.65E-16 22/38 K.MLLDPMGGIVMTNDGNAILR.E "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 2130.0636 -1 36156 22240 2 2130.065762 1066.0391 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.21 3987.6 - 2.31E+06 - - - 1.0375 - 3.862 0.72 - 1365.8 1 2 0 0.0022 20 0 0 0 0.00E+00 0.00E+00 - - - 7.6802 1 230117_WJC_METTL3_WT_vs_EV_F04.22241.22241.2 3.35E-08 15/28 K.LTILQSLGDPLYYGK.L "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 1679.9134 -1 36157 22241 2 1679.914819 840.964 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.83 3987.7 - 2.21E+06 - - - 0.8304 - 2.952 0.589 - 700.9 1 2 0 0.0014 15 0 0 0 0.00E+00 0.00E+00 - - - 6.0522 1 230117_WJC_METTL3_WT_vs_EV_F04.22242.22242.2 9.49E-09 15/28 K.GVFVQSVLPYFVATK.L "sp|Q53GQ0|DHB12_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN" 2 1653.913 -1 36158 22242 2 1653.910872 827.9638 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 8.59 3987.8 - 2.14E+06 - - - -1.3048 - 2.782 0.543 - 566.6 1 2 0 -0.0022 15 0 0 0 0.00E+00 0.00E+00 - - - 5.5664 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.22244.22244.2 0.00391 18-Nov K.LNMILVQILK[136.11].Q "sp|O14980|XPO1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 1191.7505 -1 36160 22244 2 1191.75157 596.8825 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3987.9 - 2.04E+06 - - - 0.939 - 1.927 0.383 - 263.6 1 2 0 0.0011 10 0 0 0 0.00E+00 0.00E+00 - - - 3.7005 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.22247.22247.2 0.000155 20-Sep K.EYPFILDAFQR.E sp|P42285|MTREX_HUMAN 1 1397.698 1.11 36163 22247 2 1397.697828 699.8563 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 3988.1 - 1.24E+06 - - - -0.0887 - 1.727 0.396 - 304.5 1 2 0 -0.0001 11 0 0 0 5.47E+06 4.91E+06 - - - 3.4439 0.9912 230117_WJC_METTL3_WT_vs_EV_F04.22248.22248.2 0.19 22-Dec K.IILNTAVAEFFK.S "sp|Q9H9A5|CNO10_HUMAN,tr|H7C1X9|H7C1X9_HUMAN" 2 1364.7704 -1 36164 22248 2 1364.771534 683.3925 CCR4-NOT transcription complex subunit 10 OS=Homo sapiens OX=9606 GN=CNOT10 PE=1 SV=1 6 3988.2 - 1.41E+06 - - - 0.8397 - 1.443 0.081 - 247.8 1 2 0 0.0011 12 0 0 0 0.00E+00 0.00E+00 - - - 0.6038 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.22250.22250.3 7.94E-06 13/64 R.AALGPLVTGLYDVQAFK.F "sp|P11172|UMPS_HUMAN,tr|F2Z303|F2Z303_HUMAN,tr|F2Z3P2|F2Z3P2_HUMAN,tr|F8WDG4|F8WDG4_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 5 1761.9665 3.63 36166 22250 3 1761.969669 588.3295 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 5.88 3988.4 - 727308 - - - 1.7861 - 2.52 0.428 - 200.2 1 2 0 0.0031 17 0 0 0 2.38E+06 6.57E+05 - - - 5.6459 1 230117_WJC_METTL3_WT_vs_EV_F04.22253.22253.2 1.43E-06 15/26 R.ISLPLPNFSSLNLR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1569.8879 1.72 36168 22253 2 1569.890717 785.9512 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3988.8 - 1.35E+06 - - - 1.8084 - 2.678 0.523 - 568.3 1 2 0 0.0028 14 0 0 0 9.34E+06 5.42E+06 - - - 5.375 1 230117_WJC_METTL3_WT_vs_EV_F04.22255.22255.2 4.15E-11 22/32 R.AFLQGGQEATDIALLLR.D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1814.989 -1 36170 22255 2 1814.99083 908.5018 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3988.9 - 3.36E+06 - - - 0.9818 - 3.875 0.696 - 1682.9 1 2 0 0.0018 17 0 0 0 0.00E+00 0.00E+00 - - - 7.5113 1 230117_WJC_METTL3_WT_vs_EV_F04.22256.22256.2 3.32E-05 14/22 K.LGTLSALDILIK.N "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1255.7751 -1 36171 22256 2 1255.775497 628.8948 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 5.84 3988.9 - 3.26E+06 - - - 0.2851 - 2.833 0.507 - 790.5 1 2 0 0.0004 12 0 0 0 0.00E+00 0.00E+00 - - - 5.5255 1 230117_WJC_METTL3_WT_vs_EV_F04.22257.22257.3 6.64E-06 Nov-64 R.AFLQGGQEATDIALLLR[166.11].D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1824.9973 -1 36172 22257 3 1824.998033 609.3397 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3989 - 2.63E+06 - - - 0.3918 - 2.426 0.531 - 158 1 2 0 0.0007 17 0 0 0 0.00E+00 0.00E+00 - - - 6.6988 1 230117_WJC_METTL3_WT_vs_EV_F04.22258.22258.2 3.37E-07 18/26 R.VISGVLQLGNIVFK[136.11].K sp|P35579|MYH9_HUMAN 1 1493.9061 -1 36173 22258 2 1493.907435 747.9603 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.72 3989 - 2.54E+06 - - - 0.893 - 3.262 0.578 - 875.3 1 2 0 0.0013 14 0 0 0 0.00E+00 0.00E+00 - - - 6.2767 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.22260.22260.3 0.000638 Dec-56 R.LPFLSSSNLSLDVLR[166.11].G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1669.9278 -1 36175 22260 3 1669.928766 557.6499 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3989.1 - 2.10E+06 - - - 0.5533 - 2.038 0.39 - 196.8 1 2 0 0.0009 15 0 0 0 0.00E+00 0.00E+00 - - - 4.7456 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.22261.22261.3 4.31E-05 Oct-44 R.NLQNLLILTAIK.A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1352.8391 -1 36176 22261 3 1352.83959 451.9537 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3989.2 - 1.98E+06 - - - 0.3349 - 2.428 0.484 - 291.7 1 2 0 0.0005 12 0 0 0 0.00E+00 0.00E+00 - - - 6.3948 1 230117_WJC_METTL3_WT_vs_EV_F04.22262.22262.2 2.24E-09 15/24 K.GNLEVLLFTIQSK[136.11].L "sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 5 1468.8381 1.04 36177 22262 2 1468.839564 735.4263 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6 3989.3 - 1.54E+06 - - - 1.0096 - 3.158 0.612 - 996.5 1 2 0 0.0015 13 0 0 0 3.54E+06 3.40E+06 - - - 6.5121 1 230117_WJC_METTL3_WT_vs_EV_F04.22263.22263.2 3.55E-08 17/32 R.AFLQGGQEATDIALLLR[166.11].D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1824.9973 -1 36178 22263 2 1824.99344 913.5059 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3989.4 - 1.53E+06 - - - -2.1249 - 3.436 0.672 - 868.2 1 2 0 -0.0039 17 0 0 0 0.00E+00 0.00E+00 - - - 7.0378 1 230117_WJC_METTL3_WT_vs_EV_F04.22264.22264.2 1.73E-08 15/24 K.GNLEVLLFTIQSK.L "sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 5 1460.8239 -1 36179 22264 2 1460.826641 731.4192 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6 3989.5 - 1.50E+06 - - - 1.8893 - 3.145 0.58 - 1016.9 1 2 0 0.0028 13 0 0 0 0.00E+00 0.00E+00 - - - 6.2648 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.22267.22267.3 8.69E-07 Nov-44 K.TSDLIVLGLPWK.T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1340.7704 -1 36182 22267 3 1340.772152 447.9307 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3989.8 - 1.25E+06 - - - 1.3157 - 1.951 0.489 - 212.5 1 2 0 0.0018 12 0 0 0 0.00E+00 0.00E+00 - - - 5.8439 1 230117_WJC_METTL3_WT_vs_EV_F04.22268.22268.2 1.08E-08 19/32 K.LFEMVLGPAAYNVPLPK.K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1858.0063 -1 36183 22268 2 1858.011982 930.0104 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6 3989.9 - 1.24E+06 - - - 3.07 - 3.742 0.608 - 1199.6 1 2 0 0.0057 17 0 0 0 0.00E+00 0.00E+00 - - - 6.7742 1 230117_WJC_METTL3_WT_vs_EV_F04.22269.22269.3 4.48E-08 15/52 R.HPYFYAPELLFFAK.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 1741.8868 19.64 36184 22269 3 1741.889534 581.6362 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6.75 3990 - 1.14E+06 - - - 1.561 - 2.98 0.576 - 413.7 1 2 0 0.0027 14 0 0 0 4.57E+06 2.33E+05 - - - 7.8629 0.9292 230117_WJC_METTL3_WT_vs_EV_F04.22270.22270.3 1.66 Dec-48 K.GNLEVLLFTIQSK.L "sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 5 1460.8239 -1 36185 22270 3 1460.824619 487.9486 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6 3990.1 - 1.06E+06 - - - 0.5052 - 1.334 0.089 - 106.5 1 2 0 0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 0.3134 0.9157 230117_WJC_METTL3_WT_vs_EV_F04.22276.22276.2 2.57 18-Apr R.C[160.03]FSTTLLYC[160.03]R.K sp|P60893|GPR85_HUMAN 1 1319.6002 999 36190 22276 2 1319.598884 660.8074 Probable G-protein coupled receptor 85 OS=Homo sapiens OX=9606 GN=GPR85 PE=1 SV=1 8.06 3990.7 - 3.20E+06 - - - -1.0192 - 1.073 0.097 - 41.8 4 2 0 -0.0013 10 0 0 0 1.51E+07 0.00E+00 - - - -0.3153 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.22278.22278.3 2.77E-05 Nov-52 R.VISGVLQLGNIVFK[136.11].K sp|P35579|MYH9_HUMAN 1 1493.9061 -1 36192 22278 3 1493.908064 498.976 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.72 3990.9 - 2.15E+06 - - - 1.314 - 2.391 0.445 - 168.5 1 2 0 0.002 14 0 0 0 0.00E+00 0.00E+00 - - - 5.8174 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.22281.22281.2 0.000382 22-Dec R.SQALIEELLLYK.R sp|Q5VT52|RPRD2_HUMAN 1 1418.8021 -1 36195 22281 2 1418.803988 710.4083 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3991.1 - 1.75E+06 - - - 1.3434 - 2.416 0.413 - 457.2 1 2 0 0.0019 12 0 0 0 0.00E+00 0.00E+00 - - - 4.4118 0.8728 230117_WJC_METTL3_WT_vs_EV_F04.22285.22285.3 1.06 Sep-52 R.KYHISALYVVDLKK.F "sp|Q9NYU1|UGGG2_HUMAN,sp|Q9NYU2|UGGG1_HUMAN" 2 1675.9661 999 36199 22285 3 1675.96109 559.6627 UDP-glucose:glycoprotein glucosyltransferase 2 OS=Homo sapiens OX=9606 GN=UGGT2 PE=1 SV=4 9.4 3991.5 - 1.48E+06 - - - -3.006 - 1.674 0.129 - 76 2 2 0 -0.005 14 0 0 0 6.34E+06 0.00E+00 - - - 1.2067 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.22286.22286.2 0.00314 14/20 R.VLDLVEVLVTK.Q "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1226.7486 -1 36200 22286 2 1226.750779 614.3816 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.37 3991.6 - 1.42E+06 - - - 1.7844 - 1.384 0.396 - 298.6 1 2 0 0.0022 11 0 0 0 0.00E+00 0.00E+00 - - - 2.8443 0.992 230117_WJC_METTL3_WT_vs_EV_F04.22288.22288.2 0.261 22-Aug K.NVLITDFFGSVR.K "sp|Q92643|GPI8_HUMAN,tr|B1AK81|B1AK81_HUMAN,tr|A6NEM5|A6NEM5_HUMAN" 3 1366.7245 -1 36202 22288 2 1366.727251 684.3695 GPI-anchor transamidase OS=Homo sapiens OX=9606 GN=PIGK PE=1 SV=2 5.84 3991.8 - 1.39E+06 - - - 2.0121 - 1.421 0.101 - 107.6 1 2 0 0.0028 12 0 0 0 0.00E+00 0.00E+00 - - - 0.7106 1 230117_WJC_METTL3_WT_vs_EV_F04.22289.22289.2 2.80E-08 15/24 R.DPTYFGPVLNYLR[166.11].H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1563.7961 0.84 36203 22289 2 1563.802702 782.9053 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3991.8 - 1.27E+06 - - - 4.2224 - 2.806 0.653 - 809.8 1 2 0 0.0066 13 0 0 0 6.81E+06 8.10E+06 - - - 6.51 1 230117_WJC_METTL3_WT_vs_EV_F04.22290.22290.2 8.09E-06 16/26 K.TLAESALQLLYTAK.E sp|Q9Y490|TLN1_HUMAN 1 1520.845 -1 36204 22290 2 1520.84959 761.4298 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.66 3991.9 - 1.13E+06 - - - 3.0115 - 3.009 0.529 - 612.9 1 2 0 0.0046 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7112 1 230117_WJC_METTL3_WT_vs_EV_F04.22291.22291.2 6.44E-05 15/26 R.ISLPLPNFSSLNLR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1579.8961 1.72 36205 22291 2 1579.897745 790.9554 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3992.1 - 1.04E+06 - - - 1.0108 - 2.324 0.471 - 575.2 1 2 0 0.0016 14 0 0 0 9.34E+06 5.42E+06 - - - 4.6355 1 230117_WJC_METTL3_WT_vs_EV_F04.22292.22292.2 3.85E-05 26-Dec K.TLAESALQLLYTAK[136.11].E sp|Q9Y490|TLN1_HUMAN 1 1528.8592 -1 36206 22292 2 1528.860829 765.4369 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.66 3992.2 - 992117 - - - 1.059 - 2.729 0.503 - 328.7 1 2 0 0.0016 14 0 0 0 0.00E+00 0.00E+00 - - - 5.275 0.9938 230117_WJC_METTL3_WT_vs_EV_F04.22295.22295.2 0.0988 22-Sep R.SQALIEELLLYK[136.11].R sp|Q5VT52|RPRD2_HUMAN 1 1426.8163 -1 36208 22295 2 1426.819524 714.4154 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3992.5 - 1.62E+06 - - - 2.2722 - 1.117 0.222 - 113.3 1 2 0 0.0032 12 0 0 0 0.00E+00 0.00E+00 - - - 0.9708 1 230117_WJC_METTL3_WT_vs_EV_F04.22297.22297.2 7.60E-12 16/26 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 8.77 36210 22297 2 1537.767492 769.8922 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3992.6 - 4.81E+06 - - - -1.4983 - 3.263 0.664 - 813.8 1 2 0 -0.0023 14 0 0 0 7.62E+07 8.69E+06 - - - 6.9124 1 230117_WJC_METTL3_WT_vs_EV_F04.22298.22298.2 2.36E-08 14/22 K.FFDDPMLLELAK.Q "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1437.7214 -1 36211 22298 2 1437.721927 719.868 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.03 3992.6 - 3.26E+06 - - - 0.3742 - 2.706 0.604 - 347.7 1 2 0 0.0005 12 0 0 0 0.00E+00 0.00E+00 - - - 6.1212 1 230117_WJC_METTL3_WT_vs_EV_F04.22301.22301.2 1.15E-05 20-Nov R.VLDLVEVLVTK[136.11].Q "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1234.7628 -1 36214 22301 2 1234.764132 618.3887 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.37 3992.8 - 2.11E+06 - - - 1.0868 - 2.519 0.609 - 392.2 1 2 0 0.0013 11 0 0 0 0.00E+00 0.00E+00 - - - 6.0379 1 230117_WJC_METTL3_WT_vs_EV_F04.22303.22303.2 1.37E-05 13/20 K.FVDILTNWYVR.M "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1424.7452 -1 36216 22303 2 1424.747495 713.3799 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.84 3992.9 - 1.87E+06 - - - 1.5855 - 2.563 0.456 - 615 1 2 0 0.0023 11 0 0 0 0.00E+00 0.00E+00 - - - 4.9544 0.9923 230117_WJC_METTL3_WT_vs_EV_F04.22304.22304.3 0.0819 Sep-48 R.GNTAAYLLYAFTR.L sp|P54136|SYRC_HUMAN 1 1459.746 -1 36217 22304 3 1459.746995 487.5893 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.59 3993 - 1.75E+06 - - - 0.7056 - 1.52 0.181 - 103.1 1 2 0 0.001 13 0 0 0 0.00E+00 0.00E+00 - - - 1.6929 1 230117_WJC_METTL3_WT_vs_EV_F04.22305.22305.3 2.43E-05 17/72 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 36218 22305 3 1911.183609 638.0676 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3993.1 - 1.62E+06 - - - 1.4321 - 3.109 0.504 - 338.1 1 2 0 0.0027 19 0 0 0 0.00E+00 0.00E+00 - - - 6.9451 1 230117_WJC_METTL3_WT_vs_EV_F04.22306.22306.2 0.000563 14/36 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 36219 22306 2 1911.183543 956.5977 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3993.2 - 1.21E+06 - - - 1.3976 - 2.451 0.495 - 390.3 1 2 0 0.0027 19 0 0 0 0.00E+00 0.00E+00 - - - 4.9003 0.8969 230117_WJC_METTL3_WT_vs_EV_F04.22308.22308.3 2.79 Jul-48 R.GNTAAYLLYAFTR[166.11].L sp|P54136|SYRC_HUMAN 1 1469.7542 -1 36221 22308 3 1469.753123 490.9254 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.59 3993.4 - 1.02E+06 - - - -0.7566 - 1.371 0.097 - 57.2 1 2 0 -0.0011 13 0 0 0 0.00E+00 0.00E+00 - - - 0.4767 0.9906 230117_WJC_METTL3_WT_vs_EV_F04.22309.22309.2 0.267 24-Aug R.GNTAAYLLYAFTR[166.11].L sp|P54136|SYRC_HUMAN 1 1469.7542 -1 36222 22309 2 1469.753279 735.8844 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.59 3993.5 - 1.02E+06 - - - -0.6504 - 1.361 0.169 - 95.8 1 2 0 -0.001 13 0 0 0 0.00E+00 0.00E+00 - - - 1.08 0.9992 230117_WJC_METTL3_WT_vs_EV_F04.22310.22310.2 0.00119 22-Oct K.IIGNSAFLLILK.D sp|Q16706|MA2A1_HUMAN 1 1300.8119 -1 36223 22310 2 1300.812582 651.4132 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 8.75 3993.6 - 980961 - - - 0.5558 - 1.906 0.278 - 165.3 1 2 0 0.0007 12 0 0 0 0.00E+00 0.00E+00 - - - 2.7912 1 230117_WJC_METTL3_WT_vs_EV_F04.22311.22311.2 2.32E-05 13/24 R.DPTYFGPVLNYLR.H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1553.7878 0.84 36224 22311 2 1553.78651 777.9012 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3993.7 - 933536 - - - -0.8489 - 2.478 0.523 - 637 1 2 0 -0.0013 13 0 0 0 6.81E+06 8.10E+06 - - - 5.2325 1 230117_WJC_METTL3_WT_vs_EV_F04.22312.22312.3 3.29E-08 21/52 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 -1 36225 22312 3 1537.770727 513.5972 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3993.8 - 916423 - - - 0.6054 - 3.536 0.622 - 768.4 1 2 0 0.0009 14 0 0 0 0.00E+00 0.00E+00 - - - 8.8309 1 230117_WJC_METTL3_WT_vs_EV_F04.22316.22316.2 1.18E-06 16/26 K.DAAGIAMEAIAFAR.N sp|P08240|SRPRA_HUMAN 1 1405.7024 -1 36228 22316 2 1405.709651 703.8585 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 4.37 3994.3 - 282610 - - - 5.1689 - 2.998 0.587 - 995.5 1 2 0 0.0073 14 0 0 0 0.00E+00 0.00E+00 - - - 6.1295 1 230117_WJC_METTL3_WT_vs_EV_F04.22317.22317.2 3.80E-07 14/22 K.AILC[160.03]LLLGGVER.D "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1312.7537 3.22 36229 22317 2 1312.75572 657.3841 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 6.04 3994.3 - 3.84E+06 - - - 1.5441 - 2.507 0.494 - 997.8 1 2 0 0.002 12 0 0 0 8.26E+06 2.57E+06 - - - 5.1073 1 230117_WJC_METTL3_WT_vs_EV_F04.22318.22318.3 1.15E-05 17/56 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 2.24 36230 22318 3 1519.911007 507.6435 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3994.4 - 2.13E+06 - - - 1.5751 - 2.79 0.591 - 375.4 1 2 0 0.0024 15 0 0 0 1.04E+07 4.62E+06 - - - 7.8057 1 230117_WJC_METTL3_WT_vs_EV_F04.22319.22319.2 2.44E-06 22-Dec K.AYVVLGQFLVLK[136.11].K sp|O75531|BAF_HUMAN 1 1356.8261 -1 36231 22319 2 1356.828478 679.4203 Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1 8.63 3994.4 - 2.03E+06 - - - 1.7828 - 2.514 0.497 - 461.3 1 2 0 0.0024 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1367 1 230117_WJC_METTL3_WT_vs_EV_F04.22321.22321.3 2.27E-08 19/60 K.IFEIFGPVAHPFYVLR.F sp|Q96HR8|NAF1_HUMAN 1 1904.0349 1.23 36233 22321 3 1904.039059 635.6856 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 6.75 3994.6 - 1.46E+06 - - - 2.1969 - 3.34 0.499 - 526.8 1 2 0 0.0042 16 0 0 0 3.74E+06 3.03E+06 - - - 7.1966 1 230117_WJC_METTL3_WT_vs_EV_F04.22322.22322.2 4.96E-06 22-Nov K.AYVVLGQFLVLK.K sp|O75531|BAF_HUMAN 1 1348.8119 -1 36234 22322 2 1348.814049 675.4132 Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1 8.63 3994.7 - 1.39E+06 - - - 1.6237 - 2.33 0.554 - 374.2 1 2 0 0.0022 12 0 0 0 0.00E+00 0.00E+00 - - - 5.3578 1 230117_WJC_METTL3_WT_vs_EV_F04.22323.22323.2 1.84E-08 21/28 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 1.82 36235 22323 2 1519.911307 760.9616 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3994.8 - 1.39E+06 - - - 1.7725 - 3.261 0.604 - 1907.6 1 2 0 0.0027 15 0 0 0 5.82E+06 3.20E+06 - - - 6.4074 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.22326.22326.3 5.01E-05 16/60 K.IFEIFGPVAHPFYVLR[166.11].F sp|Q96HR8|NAF1_HUMAN 1 1914.0431 1.23 36238 22326 3 1914.044503 639.0217 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 6.75 3995 - 1.05E+06 - - - 0.709 - 2.516 0.422 - 153.9 1 2 0 0.0014 16 0 0 0 3.74E+06 3.03E+06 - - - 5.612 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.22327.22327.3 0.00637 13/56 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 2.24 36239 22327 3 1529.919259 510.9796 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3995.1 - 1.01E+06 - - - 1.553 - 2.407 0.492 - 173.4 1 2 0 0.0024 15 0 0 0 1.04E+07 4.62E+06 - - - 6.3167 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.22329.22329.2 0.00137 20-Nov K.IADFGFGNFFK.S sp|Q9H0K1|SIK2_HUMAN 1 1261.6132 -1 36241 22329 2 1261.613978 631.8139 Serine\threonine-protein kinase SIK2 OS=Homo sapiens OX=9606 GN=SIK2 PE=1 SV=1 5.84 3995.3 - 859783 - - - 0.6492 - 2.321 0.363 - 424.8 1 2 0 0.0008 11 0 0 0 0.00E+00 0.00E+00 - - - 3.9997 1 230117_WJC_METTL3_WT_vs_EV_F04.22331.22331.2 4.01E-14 22/36 R.LPVVIGGLLDVDC[160.03]SEDVIK.N "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2040.0813 -1 36243 22331 2 2040.084029 1021.0479 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 3.84 3995.5 - 796807 - - - 1.3406 - 4.276 0.768 - 1293.5 1 2 0 0.0027 19 0 0 0 0.00E+00 0.00E+00 - - - 8.2849 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.22332.22332.2 7.16E-07 13/22 K.LMVEPLQAILIR.M "sp|Q13617|CUL2_HUMAN,tr|Q5T2B5|Q5T2B5_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 3 1394.8319 -1 36244 22332 2 1394.838851 698.4232 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 6 3995.6 - 735756 - - - 4.9526 - 2.571 0.39 - 672.7 1 2 0 0.0069 12 0 0 0 0.00E+00 0.00E+00 - - - 4.404 1 230117_WJC_METTL3_WT_vs_EV_F04.22333.22333.2 7.37E-07 16/28 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 1.82 36245 22333 2 1529.919889 765.9657 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3995.7 - 723077 - - - 1.9648 - 2.822 0.574 - 731.5 1 2 0 0.003 15 0 0 0 5.82E+06 3.20E+06 - - - 5.8302 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.22334.22334.2 0.000307 20-Sep R.VWEWDIPVDFK.Y "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 1432.7027 -1 36246 22334 2 1432.702943 717.3586 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 4.03 3995.8 - 695543 - - - 0.1675 - 1.715 0.431 - 196.5 1 2 0 0.0002 11 0 0 0 0.00E+00 0.00E+00 - - - 3.6835 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.22337.22337.3 4.83E-05 Oct-44 K.AILC[160.03]LLLGGVER.D "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1312.7537 -1 36248 22337 3 1312.753696 438.5918 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 6.04 3996.3 - 227710 - - - 0.0023 - 2.116 0.414 - 182.7 1 2 0 0 12 0 0 0 0.00E+00 0.00E+00 - - - 5.2333 0.9957 230117_WJC_METTL3_WT_vs_EV_F04.22338.22338.2 0.0163 16-Aug K.LLLPWLEAR.L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1109.6597 4.47 36249 22338 2 1109.664722 555.8371 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6 3996.4 - 8.25E+06 - - - 4.5113 - 1.679 0.273 - 284.7 1 2 0 0.005 9 0 0 0 9.92E+07 2.22E+07 - - - 2.555 1 230117_WJC_METTL3_WT_vs_EV_F04.22339.22339.2 4.25E-06 18-Dec R.C[160.03]WAGSLWLFK[136.11].D sp|Q9BQA1|MEP50_HUMAN 1 1274.6362 -1 36250 22339 2 1274.641442 638.3254 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 3996.4 - 5.00E+06 - - - 4.1518 - 2.353 0.543 - 464.5 1 2 0 0.0053 10 0 0 0 0.00E+00 0.00E+00 - - - 5.4384 1 230117_WJC_METTL3_WT_vs_EV_F04.22340.22340.2 6.44E-08 18-Nov R.C[160.03]WAGSLWLFK.D sp|Q9BQA1|MEP50_HUMAN 1 1266.6219 -1 36251 22340 2 1266.6283 634.3183 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 3996.5 - 2.01E+06 - - - 5.0133 - 2.265 0.579 - 346 1 2 0 0.0063 10 0 0 0 0.00E+00 0.00E+00 - - - 5.5976 1 230117_WJC_METTL3_WT_vs_EV_F04.22343.22343.2 4.06E-10 24-Dec K.LVDQNIFSFYLSR.D "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1600.8249 -1 36254 22343 2 1600.827611 801.4197 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.84 3996.9 - 1.01E+06 - - - 1.6666 - 2.548 0.652 - 422 1 2 0 0.0027 13 0 0 0 0.00E+00 0.00E+00 - - - 6.2563 0.9943 230117_WJC_METTL3_WT_vs_EV_F04.22348.22348.2 0.000795 18-Oct R.GFGFVDFLTK[136.11].Q "sp|Q9Y4C8|RBM19_HUMAN,tr|H0YIL2|H0YIL2_HUMAN" 2 1137.595 -1 36259 22348 2 1137.601034 569.8048 Probable RNA-binding protein 19 OS=Homo sapiens OX=9606 GN=RBM19 PE=1 SV=3 5.84 3997.5 - 803429 - - - 5.3068 - 2.054 0.245 - 238.8 1 2 0 0.006 10 0 0 0 0.00E+00 0.00E+00 - - - 2.8578 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.22352.22352.3 0.000688 15/64 K.ALQDEWDAVMLHSFTLR[166.11].Q "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2040.9967 -1 36263 22352 3 2041.004427 681.3395 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.54 3998 - 601196 - - - 3.8021 - 1.95 0.353 - 160.5 1 2 0 0.0078 17 0 0 0 0.00E+00 0.00E+00 - - - 4.1606 0.9999 230117_WJC_METTL3_WT_vs_EV_F04.22355.22355.3 3.89E-08 16/64 R.LLQQVGTVAQLWIYPVK.S "sp|Q5VT66|MARC1_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 2 1955.1244 -1 36266 22355 3 1955.13253 652.7154 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 8.59 3998.4 - 452925 - - - 4.1481 - 2.932 0.534 - 322.9 1 2 0 0.0081 17 0 0 0 0.00E+00 0.00E+00 - - - 7.2088 1 230117_WJC_METTL3_WT_vs_EV_F04.22359.22359.3 6.52E-08 17/44 K.FFEVILIDPFHK[136.11].A "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 4 1511.8268 -1 36269 22359 3 1511.828787 504.9495 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 5.32 3998.8 - 6.35E+06 - - - 1.3222 - 2.631 0.596 - 336.6 1 2 0 0.002 12 0 0 0 0.00E+00 0.00E+00 - - - 7.8656 1 230117_WJC_METTL3_WT_vs_EV_F04.22360.22360.3 2.35E-05 13/44 K.FFEVILIDPFHK.A "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 4 1503.8126 -1 36270 22360 3 1503.815337 502.2781 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 5.32 3998.9 - 4.35E+06 - - - 1.828 - 2.446 0.535 - 181.7 1 2 0 0.0027 12 0 0 0 0.00E+00 0.00E+00 - - - 6.9833 1 230117_WJC_METTL3_WT_vs_EV_F04.22361.22361.3 1.19E-07 15/52 K.ILGGSVLHLVLALR.G sp|Q15843|NEDD8_HUMAN 1 1459.9239 -1 36271 22361 3 1459.926863 487.6486 NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1 9.76 3998.9 - 2.34E+06 - - - 2.0508 - 2.649 0.521 - 342 1 2 0 0.003 14 0 0 0 0.00E+00 0.00E+00 - - - 6.9367 1 230117_WJC_METTL3_WT_vs_EV_F04.22363.22363.2 1.26E-07 16/24 R.DLYEDELVPLFEK.A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1608.7923 -1 36273 22363 2 1608.796107 805.4034 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3999 - 2.10E+06 - - - 2.3626 - 2.843 0.621 - 693.2 1 2 0 0.0038 13 0 0 0 0.00E+00 0.00E+00 - - - 6.3082 1 230117_WJC_METTL3_WT_vs_EV_F04.22364.22364.2 1.59E-07 15/30 K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 -1 36274 22364 2 1701.890736 851.9512 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3999.1 - 1.95E+06 - - - 1.6793 - 2.938 0.575 - 522.3 1 2 0 0.0029 16 0 0 0 0.00E+00 0.00E+00 - - - 5.9367 1 230117_WJC_METTL3_WT_vs_EV_F04.22365.22365.2 8.77E-05 14/24 R.DLYEDELVPLFEK[136.11].A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1616.8065 -1 36275 22365 2 1616.812201 809.4105 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3999.2 - 1.86E+06 - - - 3.5224 - 2.355 0.538 - 548.4 1 2 0 0.0057 13 0 0 0 0.00E+00 0.00E+00 - - - 5.2112 1 230117_WJC_METTL3_WT_vs_EV_F04.22367.22367.2 3.09E-05 14/30 K.AAGVNVEPFWPGLFAK[136.11].A sp|P05386|RLA1_HUMAN 1 1709.9021 -1 36277 22367 2 1709.905494 855.9583 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3999.3 - 1.62E+06 - - - 1.9978 - 2.85 0.51 - 454.3 1 2 0 0.0034 16 0 0 0 0.00E+00 0.00E+00 - - - 5.3817 0.999 230117_WJC_METTL3_WT_vs_EV_F04.22380.22380.2 0.00873 16-Aug R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.6 36289 22380 2 1108.656549 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4000.5 - 1.11E+08 - - - 2.991 - 1.884 0.301 - 170.6 1 2 0 0.0033 9 0 0 0 1.51E+08 9.44E+07 - - - 3.0956 1 230117_WJC_METTL3_WT_vs_EV_F04.22406.22406.2 6.99E-05 30-Nov K.LGFAGLVQEISFGTTK[136.11].D "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1674.9072 -1 36306 22406 2 1674.912021 838.4609 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 4002.3 - 0 - - - 2.8646 - 2.067 0.551 - 261.4 1 2 0 0.0048 16 0 0 0 0.00E+00 0.00E+00 - - - 4.8943 1 230117_WJC_METTL3_WT_vs_EV_F04.22410.22410.2 2.68E-07 28-Dec K.FDVILLEPPLEEYYR.E "sp|Q9HCE5|MET14_HUMAN,tr|D6RBL4|D6RBL4_HUMAN" 2 1894.9717 -1 36310 22410 2 1894.976149 948.4931 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4 4002.8 - 0 - - - 2.3652 - 2.529 0.56 - 340.9 1 2 0 0.0045 15 0 0 0 0.00E+00 0.00E+00 - - - 5.4569 0.9977 230117_WJC_METTL3_WT_vs_EV_F04.22411.22411.2 0.000432 Sep-32 R.AQLGVQAFADALLIIPK.V sp|P40227|TCPZ_HUMAN 1 1767.0295 -1 36311 22411 2 1767.037592 884.522 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.88 4003 - 56099.8 - - - 4.6038 - 1.702 0.417 - 177.2 1 2 0 0.0081 17 0 0 0 0.00E+00 0.00E+00 - - - 3.4259 1 230117_WJC_METTL3_WT_vs_EV_F04.22569.22569.2 1.18E-05 26-Dec K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.6 36327 22569 2 1618.972316 810.4902 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4032.4 - 90811.1 - - - 4.0285 - 2.124 0.539 - 335.3 1 2 0 0.0065 14 0 0 0 6.48E+06 4.05E+06 - - - 4.9104 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.22570.22570.2 0.0852 16-Nov R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.44 36328 22570 2 1108.656413 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4032.5 - 899952 - - - 2.8683 - 2.27 0.241 - 291.4 1 2 0 0.0032 9 0 0 0 2.39E+07 1.66E+07 - - - 3.1917 1 230117_WJC_METTL3_WT_vs_EV_F04.22571.22571.3 7.26E-07 21/56 R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 10.91 36329 22571 3 1555.906026 519.6409 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 4032.6 - 825022 - - - 3.3903 - 3.231 0.591 - 424.6 1 2 0 0.0053 15 0 0 0 3.46E+06 3.17E+05 - - - 8.1878 0.9991 230117_WJC_METTL3_WT_vs_EV_F04.22572.22572.2 0.00265 16-Oct R.IAIYELLFK[136.11].E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1116.6674 1.44 36330 22572 2 1116.67107 559.341 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4032.8 - 620054 - - - 3.257 - 2.154 0.311 - 242.8 1 2 0 0.0036 9 0 0 0 2.39E+07 1.66E+07 - - - 3.5568 0.968 230117_WJC_METTL3_WT_vs_EV_F04.22573.22573.3 1.28 Jun-56 R.GVMLAVDAVIAELK[136.11]K[136.11].Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1571.9292 -1 36331 22573 3 1571.934203 524.9837 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 4032.9 - 297093 - - - 3.2139 - 1.3 0.2 - 23.3 4 2 0 0.0051 15 0 0 0 0.00E+00 0.00E+00 - - - 1.1744 0.999 230117_WJC_METTL3_WT_vs_EV_F04.22576.22576.2 0.0364 26-May R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 11.97 36334 22576 2 1486.874897 744.4432 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4033.3 - 128648 - - - 2.0203 - 1.261 0.392 - 63.8 1 2 0 0.003 14 0 0 0 4.62E+05 3.86E+04 - - - 2.5173 0.9928 230117_WJC_METTL3_WT_vs_EV_F04.22577.22577.2 0.298 28-Apr R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 -1 36335 22577 2 1555.905775 778.9577 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 4033.4 - 109888 - - - 3.229 - 0.983 0.307 - 43.2 1 2 0 0.005 15 0 0 0 0.00E+00 0.00E+00 - - - 1.2648 0.9994 230117_WJC_METTL3_WT_vs_EV_F04.22579.22579.2 0.821 28-Sep R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 9.64 36337 22579 2 1581.914174 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4033.7 - 103310 - - - 3.2663 - 2.24 0.425 - 269.6 1 2 0 0.0052 15 0 0 0 7.73E+06 8.01E+05 - - - 4.1612 0.9986 230117_WJC_METTL3_WT_vs_EV_F04.22581.22581.2 0.00946 26-May K.ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1626.98 1.6 36339 22581 2 1626.982584 814.4973 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4033.9 - 63846.5 - - - 1.5919 - 1.154 0.356 - 55 1 2 0 0.0026 14 0 0 0 6.53E+06 4.08E+06 - - - 2.029 0.859 230117_WJC_METTL3_WT_vs_EV_F04.22582.22582.2 1.86 26-Mar R.APIASIHSFELDLL.- sp|Q13015|AF1Q_HUMAN 1 1524.8188 - 36340 22582 2 1524.824757 763.4167 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 4.35 4034.1 - 40217.3 - - - 3.91 - 0.64 0.206 - 27.5 1 2 0 0.006 14 0 0 0 - - - - - -0.5593 1 230117_WJC_METTL3_WT_vs_EV_F04.22594.22594.2 1.56E-07 28-Dec R.LTSFIGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1516.8865 12.37 36343 22594 2 1516.890109 759.4505 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 4036.1 - 597425 - - - 2.3917 - 2.778 0.54 - 353.5 1 2 0 0.0036 15 0 0 0 1.37E+06 1.10E+05 - - - 5.5403 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.22596.22596.3 0.000211 Nov-56 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 9.25 36345 22596 3 1581.916184 528.3103 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4036.4 - 766727 - - - 4.5369 - 2.082 0.478 - 106.1 1 2 0 0.0072 15 0 0 0 1.93E+06 2.09E+05 - - - 5.7808 0.9901 230117_WJC_METTL3_WT_vs_EV_F04.22597.22597.3 0.0396 Jun-52 K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.08 36346 22597 3 1618.973956 540.6625 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4036.5 - 474781 - - - 5.0415 - 1.445 0.3 - 46.9 1 2 0 0.0082 14 0 0 0 1.42E+06 1.32E+06 - - - 2.8607 0.9993 230117_WJC_METTL3_WT_vs_EV_F04.22599.22599.2 0.000806 30-Apr K.LGFAGLVQEISFGTTK.D "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1666.893 6.46 36348 22599 2 1666.898124 834.4538 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 4036.8 - 197559 - - - 3.0602 - 1.347 0.54 - 36.6 1 2 0 0.0051 16 0 0 0 3.47E+06 5.37E+05 - - - 3.7602 0.9909 230117_WJC_METTL3_WT_vs_EV_F04.22604.22604.2 3.82E-06 24-Aug K.SLEEIYLFSLPIK.E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN,tr|H3BNG3|H3BNG3_HUMAN,tr|H0YE27|H0YE27_HUMAN" 7 1550.8596 0.18 36353 22604 2 1550.871027 776.4371 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.53 4037.4 - 124358 - - - 7.3701 - 1.695 0.52 - 199.8 1 2 0 0.0114 13 0 0 0 3.19E+05 1.80E+06 - - - 4.2324 0.9366 230117_WJC_METTL3_WT_vs_EV_F04.22618.22618.2 8.14E-05 26-Jul R.DYLHLPPEIVPATL.H "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1576.8501 - 36365 22618 2 1576.85585 789.4323 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.35 4039.2 - 61373.2 - - - 3.6497 - 1.661 0.508 - 152.4 1 1 0 0.0058 14 0 0 0 - - - - - 4.0646 0.9987 230117_WJC_METTL3_WT_vs_EV_F04.22774.22774.2 0.0305 28-May R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 16.34 36392 22774 2 1581.914413 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4067.4 - 11490.7 - - - 3.4174 - 1.572 0.394 - 65.4 1 2 0 0.0054 15 0 0 0 1.14E+06 6.96E+04 - - - 3.0615 1 230117_WJC_METTL3_WT_vs_EV_F04.22869.22869.3 6.51E-06 15/56 R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 999 36396 22869 3 1555.903778 519.6409 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 4085.2 - 2.24E+06 - - - 1.9455 - 3.051 0.551 - 255.2 1 2 0 0.003 15 0 0 0 4.97E+06 0.00E+00 - - - 7.5929 0.9998 230117_WJC_METTL3_WT_vs_EV_F04.22874.22874.3 0.000202 Jul-52 K.ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1626.98 1.44 36401 22874 3 1626.981454 543.3339 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4085.6 - 277118 - - - 0.8974 - 1.704 0.435 - 61.9 2 2 0 0.0015 14 0 0 0 2.00E+06 1.39E+06 - - - 4.6665 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.22875.22875.2 0.00108 22-Oct R.SFLLDLLNATGK[136.11].D "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1298.7326 0.65 36402 22875 2 1298.73594 650.3736 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.55 4085.6 - 272859 - - - 2.6079 - 1.966 0.448 - 202.4 1 2 0 0.0034 12 0 0 0 8.04E+05 1.23E+06 - - - 4.1275 0.9996 230117_WJC_METTL3_WT_vs_EV_F04.22876.22876.2 0.00721 20-Sep K.GIVLLEELLPK.G sp|Q9Y3D6|FIS1_HUMAN 1 1222.7537 1.66 36403 22876 2 1222.755257 612.3841 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 4.53 4085.7 - 209401 - - - 1.293 - 1.903 0.353 - 304.3 1 2 0 0.0016 11 0 0 0 8.04E+05 4.86E+05 - - - 3.3884 1 230117_WJC_METTL3_WT_vs_EV_F04.22878.22878.2 6.75E-06 28-Dec R.QVLLSAAEAAEVILR[166.11].V sp|P78371|TCPB_HUMAN 1 1591.9173 10.01 36405 22878 2 1591.920007 796.9659 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4086 - 77831.5 - - - 1.7149 - 2.851 0.577 - 486 1 2 0 0.0027 15 0 0 0 8.50E+06 8.50E+05 - - - 5.8776 0.9985 230117_WJC_METTL3_WT_vs_EV_F04.22901.22901.3 0.026 Aug-52 K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.38 36408 22901 3 1618.971185 540.6625 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4089.9 - 110197 - - - 3.3299 - 1.738 0.307 - 81 1 2 0 0.0054 14 0 0 0 1.69E+06 1.22E+06 - - - 3.4302 0.9997 230117_WJC_METTL3_WT_vs_EV_F04.22903.22903.3 0.012 Sep-52 R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 4.41 36410 22903 3 1486.876394 496.6312 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4090.1 - 46260.2 - - - 3.0272 - 2.071 0.404 - 96 1 2 0 0.0045 14 0 0 0 1.22E+06 2.77E+05 - - - 4.9777 1 230117_WJC_METTL3_WT_vs_EV_F04.22904.22904.2 1.97E-05 24-Sep K.SLEEIYLFSLPIK[136.11].E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN,tr|H3BNG3|H3BNG3_HUMAN,tr|H0YE27|H0YE27_HUMAN" 7 1558.8738 0.36 36411 22904 2 1558.876196 780.4442 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.53 4090.3 - 43284 - - - 1.5389 - 1.954 0.536 - 238.5 1 2 0 0.0024 13 0 0 0 4.78E+05 1.34E+06 - - - 4.7184 0.9995 230117_WJC_METTL3_WT_vs_EV_F04.22905.22905.2 0.0462 26-May R.LLVPTQFVGAIIGK[136.11].E "sp|O00425|IF2B3_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 3 1462.9003 1.16 36412 22905 2 1462.903401 732.4574 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 4090.4 - 37690.2 - - - 2.1286 - 1.109 0.554 - 52.1 1 2 0 0.0031 14 0 0 0 7.89E+05 6.82E+05 - - - 3.3915 0.999 230117_WJC_METTL3_WT_vs_EV_F04.22907.22907.2 0.000392 30-Jun K.LGFAGLVQEISFGTTK[136.11].D "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1674.9072 6.29 36414 22907 2 1674.913615 838.4609 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 4090.7 - 30225.2 - - - 3.8163 - 1.636 0.495 - 59 1 2 0 0.0064 16 0 0 0 3.22E+06 5.12E+05 - - - 3.9053 0.9971 230117_WJC_METTL3_WT_vs_EV_F04.22908.22908.2 0.00703 22-May R.LLTSFLPAQLLR.L "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|H0YFX4|H0YFX4_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 14 1370.8286 1.06 36415 22908 2 1370.834197 686.4216 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 9.75 4090.8 - 24423.1 - - - 4.1034 - 1.263 0.41 - 79.1 1 2 0 0.0056 12 0 0 0 3.47E+05 3.27E+05 - - - 2.6818 0.9982 230117_WJC_METTL3_WT_vs_EV_F04.22910.22910.2 0.000113 28-Aug K.FDVILLEPPLEEYYR.E "sp|Q9HCE5|MET14_HUMAN,tr|D6RBL4|D6RBL4_HUMAN" 2 1894.9717 999 36417 22910 2 1894.980969 948.4931 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4 4091 - 18048 - - - 4.9088 - 1.972 0.496 - 142.4 1 2 0 0.0093 15 0 0 0 4.09E+05 0.00E+00 - - - 4.371 0.9686 230117_WJC_METTL3_WT_vs_EV_F04.22913.22913.2 6.53E-05 26-Aug R.DYLHLPPEIVPATL.H "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1576.8501 - 36418 22913 2 1576.854321 789.4323 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.35 4091.5 - 209601 - - - 2.68 - 1.762 0.533 - 201.5 1 1 0 0.0042 14 0 0 0 - - - - - 4.3979 1 230117_WJC_METTL3_WT_vs_EV_F04.22914.22914.2 1.11E-05 22-Sep R.TFC[160.03]QLILDPIFK.V sp|P13639|EF2_HUMAN 1 1493.7952 3.09 36419 22914 2 1493.798417 747.9049 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.5 4091.7 - 135684 - - - 2.1382 - 1.738 0.573 - 278.5 1 2 0 0.0032 12 0 0 0 4.96E+05 1.61E+05 - - - 4.7265 1 230117_WJC_METTL3_WT_vs_EV_F04.22915.22915.2 1.00E-07 13/32 R.WVGGPEIELIAIATGGR.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1737.9414 5.28 36420 22915 2 1737.943361 869.978 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 4091.8 - 108891 - - - 1.1456 - 2.483 0.584 - 426.5 1 2 0 0.002 17 0 0 0 3.48E+05 6.59E+04 - - - 5.5898 0.9974 230117_WJC_METTL3_WT_vs_EV_F04.22916.22916.3 0.0276 Jun-56 R.LTSFIGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1516.8865 4.7 36421 22916 3 1516.891121 506.6361 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 4091.9 - 103740 - - - 3.0589 - 1.224 0.34 - 35.2 1 2 0 0.0046 15 0 0 0 4.39E+05 9.33E+04 - - - 2.8568 1 230117_WJC_METTL3_WT_vs_EV_F04.22955.22955.2 0.0257 28-Oct R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 12 36427 22955 2 1581.915493 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4098.3 - 89489.4 - - - 4.1001 - 2.605 0.537 - 345.2 1 2 0 0.0065 15 0 0 0 1.68E+06 1.40E+05 - - - 5.3591 0.8794 230117_WJC_METTL3_WT_vs_EV_F05.03001.03001.2 2.53 12-Jun K.ATVEDEK.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 790.3709 3.77 36461 3001 2 790.369352 396.1927 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 1291.6 - 295135 - - - -1.9118 - 0.819 0.188 - 66.2 1 2 0 -0.0015 7 0 0 0 2.95E+06 7.82E+05 - - - -0.2036 0.8987 230117_WJC_METTL3_WT_vs_EV_F05.03478.03478.2 0.145 12-Jun K.HPELADK.N "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 808.4079 1.63 36469 3478 2 808.404361 405.2112 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 5.32 1376.3 - 153581 - - - -4.4 - 1.093 0.227 - 102.3 1 2 0 -0.0036 7 0 0 0 9.65E+06 5.93E+06 - - - 0.9983 0.9693 230117_WJC_METTL3_WT_vs_EV_F05.03608.03608.2 0.343 14-May K.SFATASHR.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 875.425 0.71 36473 3608 2 875.42507 438.7198 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.49 1399.4 - 73527.2 - - - 0.1199 - 0.962 0.136 - 88.5 1 2 0 0.0001 8 0 0 0 1.89E+06 2.66E+06 - - - -0.0714 0.9837 230117_WJC_METTL3_WT_vs_EV_F05.03640.03640.2 0.0319 12-May R.NDEELNK[136.11].L "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 17 868.4018 0.09 36476 3640 2 868.40391 435.2082 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 4.14 1404.9 - 75568.7 - - - 2.4574 - 1.02 0.167 - 75 1 2 0 0.0021 7 0 0 0 2.52E+06 2.90E+07 - - - 0.3365 0.9668 230117_WJC_METTL3_WT_vs_EV_F05.04002.04002.2 0.344 12-Jun R.ITPEEAK[136.11].Y sp|P62701|RS4X_HUMAN 1 794.4265 0.9 36483 4002 2 794.424956 398.2205 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.53 1470.2 - 204195 - - - -1.9863 - 1.171 0.165 - 157 1 2 0 -0.0016 7 0 0 0 8.36E+06 9.31E+06 - - - 0.7594 0.9496 230117_WJC_METTL3_WT_vs_EV_F05.04106.04106.2 5.84 12-May R.NSTIPTK.Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 759.4127 9.49 36486 4106 2 759.414068 380.7136 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 1488.8 - 296358 - - - 1.8422 - 1.074 0.023 - 114.6 1 2 0 0.0014 7 0 0 0 2.31E+07 2.43E+06 - - - -0.5634 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.04137.04137.2 0.615 12-Jun R.FTDEESR[166.11].V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 892.3802 0.77 36490 4137 2 892.380559 447.1974 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1494.1 - 939892 - - - 0.4068 - 1.278 0.303 - 124.7 1 2 0 0.0004 7 0 0 0 2.03E+07 2.62E+07 - - - 2.0561 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.04138.04138.2 0.00207 18-Nov R.IAGQVAAANK.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 941.5294 1.49 36491 4138 2 941.52979 471.772 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1494.2 - 171190 - - - 0.3824 - 2.202 0.377 - 340.5 1 2 0 0.0004 10 0 0 0 1.22E+07 8.18E+06 - - - 4.0288 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.04217.04217.2 0.00243 14-Aug R.NTEEEGLK[136.11].Y "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 926.4436 1.34 36495 4217 2 926.442402 464.2291 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.25 1507.9 - 488184 - - - -1.3374 - 1.659 0.416 - 355.7 1 2 0 -0.0012 8 0 0 0 2.75E+07 2.06E+07 - - - 3.6399 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.04240.04240.2 0.0453 12-Jul R.EAQVNVR[166.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 824.438 0.05 36497 4240 2 824.438181 413.2263 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1511.8 - 529040 - - - 0.2365 - 1.439 0.22 - 326.9 1 2 0 0.0002 7 0 0 0 1.43E+07 2.83E+08 - - - 1.819 0.9871 230117_WJC_METTL3_WT_vs_EV_F05.04245.04245.2 0.328 12-May R.EAQVNVR.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 814.4297 0.05 36498 4245 2 814.42946 408.2221 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1512.6 - 510232 - - - -0.3143 - 1.106 0.18 - 156.9 1 2 0 -0.0003 7 0 0 0 1.42E+07 2.61E+08 - - - 0.6896 0.9826 230117_WJC_METTL3_WT_vs_EV_F05.04304.04304.2 0.0985 12-May K.HTLTQIK.D sp|P40227|TCPZ_HUMAN 1 839.4865 11.72 36502 4304 2 839.486128 420.7505 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 8.76 1522.9 - 171960 - - - -0.4455 - 0.924 0.272 - 56.6 4 2 0 -0.0004 7 0 0 0 7.96E+06 6.79E+05 - - - 0.5305 0.8906 230117_WJC_METTL3_WT_vs_EV_F05.04419.04419.2 3.24 12-May K.EQSIVEK.F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 831.4338 733.54 36510 4419 2 831.432896 416.7242 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 1542.5 - 2.51E+07 - - - -1.0849 - 1.179 0.014 - 170.8 2 2 0 -0.0009 7 0 0 0 7.68E+08 1.05E+06 - - - -0.4686 0.9953 230117_WJC_METTL3_WT_vs_EV_F05.04517.04517.2 0.00224 16-Jul K.VLENAEGAR.T "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 957.488 6.39 36515 4517 2 957.486865 479.7513 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.53 1559.3 - 309275 - - - -1.1426 - 1.518 0.227 - 190.5 1 2 0 -0.0011 9 0 0 0 5.61E+06 8.78E+05 - - - 1.9248 0.8748 230117_WJC_METTL3_WT_vs_EV_F05.04920.04920.2 1.67 14-May R.TSIEVGVK.G sp|Q03052|PO3F1_HUMAN 1 831.4702 999 36516 4920 2 831.472467 416.7424 "POU domain, class 3, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU3F1 PE=2 SV=3" 5.66 1633 - 2.48E+06 - - - 2.7469 - 1.026 0.036 - 74.6 5 2 0 0.0023 8 0 0 0 2.11E+09 0.00E+00 - - - -0.9286 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.04991.04991.2 0.106 16-Aug K.TIAPQNAPR.D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 966.5247 0.35 36520 4991 2 966.52453 484.2696 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1645.7 - 190267 - - - -0.1542 - 1.47 0.26 - 233.4 1 2 0 -0.0001 9 0 0 0 2.70E+07 7.70E+07 - - - 2.0759 0.8681 230117_WJC_METTL3_WT_vs_EV_F05.05013.05013.2 5.71 16-Jun K.TIAPQNAPR[166.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 976.5329 0.3 36521 5013 2 976.52996 489.2738 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1649.5 - 737172 - - - -3.0608 - 1.09 0.123 - 89.9 1 2 0 -0.003 9 0 0 0 2.70E+07 8.87E+07 - - - 0.1979 0.9339 230117_WJC_METTL3_WT_vs_EV_F05.05145.05145.2 1.59 12-Jun K.LVEESVK[136.11].H "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 810.4578 0.22 36523 5145 2 810.455708 406.2362 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 1672.5 - 449081 - - - -2.6232 - 1.289 0.093 - 136 1 2 0 -0.0021 7 0 0 0 4.84E+06 2.24E+07 - - - 0.5316 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.05327.05327.2 0.075 12-Jun K.MYEEHLK[136.11].R "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 956.4517 0.72 36531 5327 2 956.452709 479.2331 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.38 1704.4 - 245033 - - - 1.0518 - 1.181 0.26 - 162.4 1 2 0 0.001 7 0 0 0 8.11E+06 1.12E+07 - - - 1.4882 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.05485.05485.2 0.000137 14-Sep K.EHC[160.03]LVGVK.G sp|Q86U44|MTA70_HUMAN 1 940.48 8.91 36539 5485 2 940.480541 471.2473 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 1732.9 - 1.90E+06 - - - 0.5359 - 1.683 0.453 - 421.9 1 2 0 0.0005 8 0 0 0 6.03E+07 6.77E+06 - - - 3.9567 0.996 230117_WJC_METTL3_WT_vs_EV_F05.05496.05496.2 1.08 12-Jul K.ITITNDK.G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 803.4389 12.61 36540 5496 2 803.440214 402.7267 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1734.8 - 577043 - - - 1.6566 - 1.335 0.163 - 188 1 2 0 0.0013 7 0 0 0 1.17E+08 9.27E+06 - - - 1.16 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.05502.05502.2 3.15 12-Jul K.ITITNDK[136.11].G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 811.4531 12.61 36541 5502 2 811.455513 406.7338 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1735.9 - 118509 - - - 2.9946 - 1.427 0.238 - 157.2 1 2 0 0.0024 7 0 0 0 1.17E+08 9.27E+06 - - - 1.9248 0.9804 230117_WJC_METTL3_WT_vs_EV_F05.05734.05734.2 0.742 12-Aug K.NADELVK.Q "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 5 787.4076 10.84 36547 5734 2 787.408708 394.7111 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.37 1777.8 - 554388 - - - 1.4287 - 1.272 0.029 - 196.2 1 2 0 0.0011 7 0 0 0 2.92E+07 2.69E+06 - - - 0.0172 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.05868.05868.2 0.579 12-Jul K.LAEPYGK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 776.4069 1.37 36551 5868 2 776.408203 389.2107 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1801.8 - 258289 - - - 1.7362 - 1.354 0.161 - 211.1 1 2 0 0.0013 7 0 0 0 1.66E+07 1.21E+07 - - - 1.19 0.9896 230117_WJC_METTL3_WT_vs_EV_F05.06042.06042.2 1.05 18-Jul K.GSAITGPVAK[136.11].E "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 907.5218 1.76 36556 6042 2 907.523376 454.7682 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.75 1832 - 157468 - - - 1.7013 - 1.174 0.132 - 114.8 1 2 0 0.0015 10 0 0 0 1.43E+07 8.11E+06 - - - 0.4632 1 230117_WJC_METTL3_WT_vs_EV_F05.06202.06202.2 0.00104 16-Nov R.VTDALNATR.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 959.5036 2.16 36561 6202 2 959.505093 480.7591 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1861.5 - 424028 - - - 1.5466 - 2.369 0.435 - 487.4 1 2 0 0.0015 9 0 0 0 7.01E+07 3.24E+07 - - - 4.7486 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.06211.06211.2 0.000513 16-Oct R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 2.16 36562 6211 2 969.512917 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1863 - 310266 - - - 1.0706 - 2.005 0.459 - 425.2 1 2 0 0.001 9 0 0 0 7.01E+07 3.24E+07 - - - 4.4434 0.9799 230117_WJC_METTL3_WT_vs_EV_F05.06632.06632.2 0.174 14-Jul K.VISELNGK.N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 858.4811 1.11 36578 6632 2 858.481264 430.2478 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1938.6 - 260978 - - - 0.2108 - 0.966 0.169 - 144.1 1 2 0 0.0002 8 0 0 0 1.62E+07 1.47E+07 - - - 0.1849 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.06896.06896.2 0.00109 24-Aug K.GPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1199.6146 999 36587 6896 2 1199.615731 600.8146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1984.6 - 75653.1 - - - 0.9295 - 1.774 0.407 - 168 1 2 0 0.0011 13 0 0 0 7.50E+06 0.00E+00 - - - 3.518 0.991 230117_WJC_METTL3_WT_vs_EV_F05.06918.06918.2 0.31 12-May K.IIAPPER[166.11].K "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 12 804.4733 0.82 36590 6918 2 804.473542 403.2439 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 1988.3 - 145825 - - - 0.2909 - 1.017 0.22 - 102.4 1 2 0 0.0002 7 0 0 0 3.60E+07 4.42E+07 - - - 0.7193 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.06920.06920.2 0.0707 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 458.83 36591 6920 2 776.383404 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1988.5 - 913416 - - - 2.1909 - 1.496 0.245 - 184 1 2 0 0.0017 7 0 0 0 5.26E+09 1.15E+07 - - - 2.1263 0.9574 230117_WJC_METTL3_WT_vs_EV_F05.06931.06931.2 5.49 14-Jun R.GTLDPVEK.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 857.4494 13.24 36592 6931 2 857.450768 429.732 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.37 1990.4 - 286312 - - - 1.5394 - 1.076 0.034 - 103.4 1 2 0 0.0013 8 0 0 0 9.13E+07 6.89E+06 - - - -0.4874 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.07018.07018.2 0.00481 16-Aug K.SAAMTLNER[166.11].F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1001.484 0.81 36595 7018 2 1001.485647 501.7493 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 2005.7 - 142708 - - - 1.6945 - 1.552 0.394 - 235.6 1 2 0 0.0017 9 0 0 0 1.61E+07 2.00E+07 - - - 3.2222 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.07056.07056.2 0.00758 16-Aug K.SAAMTLNER.F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 991.4757 0.81 36598 7056 2 991.475889 496.7451 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 2012.3 - 530190 - - - 0.2108 - 1.657 0.389 - 225.9 1 2 0 0.0002 9 0 0 0 1.61E+07 2.00E+07 - - - 3.3751 0.9896 230117_WJC_METTL3_WT_vs_EV_F05.07116.07116.2 2.37 12-May R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 0.93 36599 7116 2 776.382416 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2022.9 - 415209 - - - 0.9184 - 1.074 0.199 - 81.6 4 2 0 0.0007 7 0 0 0 8.65E+07 9.31E+07 - - - 0.4679 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.07155.07155.2 0.00589 14-Jul K.GANPVEIR.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 854.461 1.86 36601 7155 2 854.46086 428.2378 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 2029.8 - 346349 - - - -0.1826 - 1.205 0.309 - 188.5 1 2 0 -0.0002 8 0 0 0 5.86E+07 3.14E+07 - - - 1.8856 0.9498 230117_WJC_METTL3_WT_vs_EV_F05.07180.07180.2 0.199 12-Jul R.IGVITNR[166.11].E sp|P62701|RS4X_HUMAN 1 781.4686 0.89 36602 7180 2 781.468696 391.7416 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2034.3 - 264482 - - - 0.1779 - 1.188 0 - 125.7 1 2 0 0.0001 7 0 0 0 1.82E+07 2.04E+07 - - - -0.4132 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.07204.07204.2 0.00547 14-Jul K.GANPVEIR[166.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 864.4693 1.88 36607 7204 2 864.470238 433.2419 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 2038 - 480131 - - - 1.1013 - 1.253 0.344 - 193 1 2 0 0.001 8 0 0 0 5.87E+07 3.12E+07 - - - 2.2617 0.999 230117_WJC_METTL3_WT_vs_EV_F05.07241.07241.2 0.0744 14-Jun K.VGEVIVTK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.5208 2.03 36610 7241 2 851.522538 426.7677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2044.6 - 165331 - - - 2.0775 - 1.599 0.28 - 117 1 2 0 0.0018 8 0 0 0 1.10E+08 5.42E+07 - - - 2.5241 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.07251.07251.2 0.0547 14-Sep K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 2.03 36611 7251 2 843.50855 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2046.4 - 685192 - - - 2.3485 - 1.962 0.323 - 220.2 1 2 0 0.002 8 0 0 0 1.10E+08 5.42E+07 - - - 3.4587 0.9949 230117_WJC_METTL3_WT_vs_EV_F05.07377.07377.2 0.0996 12-Jun R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 129.77 36619 7377 2 776.381351 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2068.4 - 128749 - - - -0.4534 - 1.306 0.215 - 134.1 1 2 0 -0.0004 7 0 0 0 3.78E+07 2.91E+05 - - - 1.4748 0.999 230117_WJC_METTL3_WT_vs_EV_F05.07505.07505.2 0.00342 16-Aug K.VTMQNLNDR.L "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 8 1089.5237 999 36625 7505 2 1089.523442 545.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.81 2090.7 - 154727 - - - -0.2295 - 1.554 0.363 - 192.8 1 2 0 -0.0003 9 0 0 0 6.93E+06 0.00E+00 - - - 2.9974 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.07537.07537.3 0.0185 Oct-44 R.TLVAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1299.763 0.67 36627 7537 3 1299.762889 434.2616 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2096.2 - 253407 - - - -0.0508 - 1.76 0.307 - 104.4 1 2 0 -0.0001 12 0 0 0 6.44E+06 9.56E+06 - - - 3.5297 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.07649.07649.2 0.0207 16-Jul R.VLNTNIDGR[166.11].R "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1010.5384 1.48 36637 7649 2 1010.542781 506.2765 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.81 2115.4 - 220926 - - - 4.3076 - 1.318 0.348 - 144.5 1 2 0 0.0044 9 0 0 0 2.69E+07 1.82E+07 - - - 2.4088 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.07652.07652.2 0.00656 16-Jul R.VLNTNIDGR.R "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1000.5302 1.54 36638 7652 2 1000.53234 501.2724 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.81 2115.8 - 246159 - - - 2.1808 - 1.384 0.423 - 207.4 1 2 0 0.0022 9 0 0 0 2.69E+07 1.75E+07 - - - 3.1048 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.07666.07666.2 0.27 14-Aug R.VLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 815.4753 0.96 36641 7666 2 815.474568 408.7449 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 2117.9 - 582270 - - - -0.8596 - 1.467 0.299 - 285.2 1 2 0 -0.0007 8 0 0 0 3.05E+07 3.18E+07 - - - 2.405 0.9911 230117_WJC_METTL3_WT_vs_EV_F05.07756.07756.2 0.294 14-Aug R.FSELTAEK.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 923.46 7.17 36652 7756 2 923.463244 462.7373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2132.8 - 2.16E+06 - - - 3.4988 - 1.178 0.23 - 103.9 1 2 0 0.0032 8 0 0 0 3.55E+07 4.95E+06 - - - 1.2328 0.9468 230117_WJC_METTL3_WT_vs_EV_F05.07759.07759.2 24.6 12-Jun R.IPPVAVR[166.11].L "sp|Q14839|CHD4_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A0G2JM70|A0A0G2JM70_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|V9GYG6|V9GYG6_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 760.4835 0.001 36653 7759 2 760.483575 381.249 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 2133.2 - 417243 - - - 0.1262 - 1.064 0.073 - 115.2 3 2 0 0.0001 7 0 0 0 0.00E+00 5.63E+07 - - - -0.4364 0.947 230117_WJC_METTL3_WT_vs_EV_F05.07837.07837.2 0.000214 16-Oct Y.PDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 953.5546 999 36660 7837 2 953.557929 477.7846 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2146.4 - 475925 - - - 3.51 - 1.933 0.454 - 349 1 1 0 0.0033 9 0 0 0 2.89E+07 0.00E+00 - - - 4.2999 1 230117_WJC_METTL3_WT_vs_EV_F05.07846.07846.2 6.39E-07 14/18 R.YPDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 1116.6179 798.97 36662 7846 2 1116.61959 559.3162 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2147.7 - 933883 - - - 1.5045 - 1.937 0.557 - 590 1 2 0 0.0017 10 0 0 0 7.01E+07 8.77E+04 - - - 4.9999 0.8681 230117_WJC_METTL3_WT_vs_EV_F05.07853.07853.2 0.359 12-Jun D.VIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 784.4807 7.89 36663 7853 2 784.481535 393.2476 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 2148.9 - 518906 - - - 1.0784 - 1.319 0.251 - 168.3 1 1 0 0.0008 7 0 0 0 6.57E+07 8.32E+06 - - - 1.7719 0.958 230117_WJC_METTL3_WT_vs_EV_F05.07926.07926.2 3.81 14-Jun K.HVVFIAQR.R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 968.5556 9.55 36668 7926 2 968.557754 485.2851 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 9.76 2161.6 - 97461.3 - - - 2.2394 - 1.153 0.023 - 155.6 1 2 0 0.0022 8 0 0 0 8.80E+06 9.21E+05 - - - -0.3604 1 230117_WJC_METTL3_WT_vs_EV_F05.07938.07938.2 0.000271 16-Oct R.TLLEGEESR.M sp|P04264|K2C1_HUMAN 1 1032.5088 48.26 36670 7938 2 1032.509402 517.2617 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.25 2163.5 - 914002 - - - 0.6276 - 2.105 0.495 - 353.1 1 2 0 0.0006 9 0 0 0 4.22E+07 8.75E+05 - - - 4.8502 0.9838 230117_WJC_METTL3_WT_vs_EV_F05.07940.07940.2 23.1 12-Jun R.IPPVAVR[166.11].L "sp|Q14839|CHD4_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A0G2JM70|A0A0G2JM70_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|V9GYG6|V9GYG6_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 760.4835 0.001 36671 7940 2 760.484008 381.249 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 2163.8 - 400746 - - - 0.6956 - 1.215 0.074 - 136.7 1 2 0 0.0005 7 0 0 0 0.00E+00 6.93E+07 - - - 0.2045 0.9069 230117_WJC_METTL3_WT_vs_EV_F05.08081.08081.2 0.14 12-May R.FC[160.03]ALEEK.C "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 895.411 0.3 36686 8081 2 895.408447 448.7128 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2187.4 - 190969 - - - -2.7998 - 1.094 0.139 - 75.1 1 2 0 -0.0025 7 0 0 0 8.24E+06 2.73E+07 - - - 0.3515 0.9849 230117_WJC_METTL3_WT_vs_EV_F05.08104.08104.2 2.56 14-Jul K.VC[160.03]NPIITK.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 943.5161 15.48 36689 8104 2 943.516173 472.7653 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.19 2191.1 - 151706 - - - 0.0901 - 1.222 0.105 - 114.4 1 2 0 0.0001 8 0 0 0 8.66E+07 5.59E+06 - - - 0.4212 0.9905 230117_WJC_METTL3_WT_vs_EV_F05.08182.08182.2 1.18 12-Sep K.VLAAVYK.A "sp|P05062|ALDOB_HUMAN,sp|P04075|ALDOA_HUMAN,sp|P09972|ALDOC_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|A8MVZ9|A8MVZ9_HUMAN,tr|A0A3B3IS80|A0A3B3IS80_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|A0A087WXX2|A0A087WXX2_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 10 762.464 1.91 36697 8182 2 762.46591 382.2393 Fructose-bisphosphate aldolase B OS=Homo sapiens OX=9606 GN=ALDOB PE=1 SV=2 8.56 2204.4 - 401830 - - - 2.5365 - 1.291 0.122 - 237.8 1 2 0 0.0019 7 0 0 0 1.69E+08 8.86E+07 - - - 0.7508 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.08195.08195.2 0.115 12-Jun K.VLAAVYK[136.11].A "sp|P05062|ALDOB_HUMAN,sp|P04075|ALDOA_HUMAN,sp|P09972|ALDOC_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|A8MVZ9|A8MVZ9_HUMAN,tr|A0A3B3IS80|A0A3B3IS80_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|A0A087WXX2|A0A087WXX2_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 10 770.4782 1.91 36701 8195 2 770.479062 386.2464 Fructose-bisphosphate aldolase B OS=Homo sapiens OX=9606 GN=ALDOB PE=1 SV=2 8.56 2206.3 - 694984 - - - 1.1499 - 1.405 0.223 - 138.8 1 2 0 0.0009 7 0 0 0 1.69E+08 8.86E+07 - - - 1.7652 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.08211.08211.2 0.136 12-Jun R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 257 36703 8211 2 808.434016 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2209 - 737611 - - - 1.1702 - 1.331 0.264 - 67.4 1 2 0 0.0009 7 0 0 0 1.23E+08 4.80E+05 - - - 1.8966 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.08231.08231.2 0.000565 18-Sep K.LLNTVEETTK[136.11].D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1154.6274 0.16 36706 8231 2 1154.630381 578.321 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2212.3 - 488006 - - - 2.5653 - 2.025 0.388 - 197 1 2 0 0.003 10 0 0 0 3.62E+06 2.22E+07 - - - 3.8753 0.9927 230117_WJC_METTL3_WT_vs_EV_F05.08236.08236.2 0.148 18-Oct K.LLNTVEETTK.D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1146.6132 0.16 36707 8236 2 1146.617976 574.3139 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2213.1 - 843210 - - - 4.1487 - 1.473 0.224 - 242.8 1 2 0 0.0048 10 0 0 0 3.47E+06 2.22E+07 - - - 1.775 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.08259.08259.2 0.202 14-Jul R.ILSGVVTK.M "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 815.5117 0.86 36711 8259 2 815.512652 408.7631 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 2216.7 - 180286 - - - 1.2238 - 1.622 0.153 - 128.1 1 2 0 0.001 8 0 0 0 3.40E+07 3.93E+07 - - - 1.6294 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.08261.08261.2 1.18 12-Jul K.LVTDLTK.V "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 788.4644 10.94 36712 8261 2 788.465368 395.2395 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.84 2216.9 - 648650 - - - 1.2658 - 1.356 0.157 - 124.8 1 2 0 0.001 7 0 0 0 2.64E+07 2.41E+06 - - - 1.1652 0.994 230117_WJC_METTL3_WT_vs_EV_F05.08267.08267.2 0.215 14-Jul R.ILSGVVTK[136.11].M "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 823.5259 0.86 36714 8267 2 823.527092 412.7702 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 2217.8 - 536563 - - - 1.5033 - 1.478 0.084 - 109.7 1 2 0 0.0012 8 0 0 0 3.39E+07 3.93E+07 - - - 0.8393 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.08276.08276.2 0.0868 14-Aug R.IVVAAVAR[166.11].A "sp|Q7Z2T5|TRM1L_HUMAN,tr|X6RK96|X6RK96_HUMAN" 2 807.5206 1.66 36715 8276 2 807.52157 404.7676 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 9.75 2219.3 - 822742 - - - 1.2099 - 1.512 0.26 - 128.1 1 2 0 0.001 8 0 0 0 5.54E+07 3.34E+07 - - - 2.2079 0.9795 230117_WJC_METTL3_WT_vs_EV_F05.08315.08315.2 0.158 18-Jun R.ASAVSELSPR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1025.5381 0.84 36721 8315 2 1025.537514 513.7763 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2225.7 - 125774 - - - -0.5656 - 1.17 0.134 - 57.3 1 2 0 -0.0006 10 0 0 0 1.08E+07 1.28E+07 - - - 0.4688 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.08354.08354.2 0.000196 18-Sep R.ASAVSELSPR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1015.5298 0.84 36728 8354 2 1015.533791 508.7722 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2231.9 - 149134 - - - 3.9063 - 1.678 0.296 - 188.4 1 2 0 0.004 10 0 0 0 1.08E+07 1.28E+07 - - - 2.6708 0.9802 230117_WJC_METTL3_WT_vs_EV_F05.08402.08402.2 0.802 12-Jun R.LLPAEVK[136.11].A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 776.4887 1.35 36731 8402 2 776.488396 389.2516 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6 2240.3 - 1.71E+06 - - - -0.4443 - 1.187 0.134 - 121.6 2 2 0 -0.0003 7 0 0 0 2.46E+08 1.82E+08 - - - 0.4393 0.9869 230117_WJC_METTL3_WT_vs_EV_F05.08435.08435.2 2.67 12-Jun K.SEITELR.R "sp|P13645|K1C10_HUMAN,sp|Q8TDM6|DLG5_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 3 846.4447 4.72 36737 8435 2 846.444099 424.2296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2245.5 - 352943 - - - -0.7065 - 1.256 0.148 - 229.2 1 2 0 -0.0006 7 0 0 0 1.21E+07 2.55E+06 - - - 0.8562 1 230117_WJC_METTL3_WT_vs_EV_F05.08446.08446.2 1.27E-05 13/20 K.FAEALGSTEAK[136.11].A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1130.5699 0.43 36740 8446 2 1130.571533 566.2922 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2247 - 329533 - - - 1.4409 - 2.354 0.533 - 525.2 1 2 0 0.0016 11 0 0 0 6.26E+06 1.46E+07 - - - 5.2932 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.08547.08547.2 0.77 16-Aug R.ILQDSLGGR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 967.5326 0.33 36750 8547 2 967.533151 484.7736 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2263.9 - 111445 - - - 0.555 - 1.492 0.2 - 174.5 1 2 0 0.0005 9 0 0 0 5.96E+06 1.80E+07 - - - 1.6756 0.9897 230117_WJC_METTL3_WT_vs_EV_F05.08577.08577.2 0.786 16-Jun R.ILQDSLGGR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 957.5243 0.33 36758 8577 2 957.526001 479.7694 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2268.4 - 120728 - - - 1.7305 - 1.01 0.19 - 87.6 1 2 0 0.0017 9 0 0 0 5.96E+06 1.80E+07 - - - 0.4726 0.9476 230117_WJC_METTL3_WT_vs_EV_F05.08681.08681.2 8.09 12-Jun R.LLEQGIR.V "sp|P28340|DPOD1_HUMAN,sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 7 827.4865 1.64 36772 8681 2 827.486893 414.7505 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 6 2285.7 - 186336 - - - 0.4725 - 1.14 0.003 - 103.7 1 2 0 0.0004 7 0 0 0 3.61E+07 2.20E+07 - - - -0.5218 0.9875 230117_WJC_METTL3_WT_vs_EV_F05.08760.08760.2 0.14 12-Jul K.NIQVVVR[166.11].C "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 836.5108 0.28 36784 8760 2 836.508271 419.2627 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 9.75 2298.1 - 929217 - - - -2.9719 - 1.4 0.269 - 223.6 1 2 0 -0.0025 7 0 0 0 2.12E+07 7.47E+07 - - - 2.0932 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.08812.08812.2 0.0196 12-Jul R.AMIIAER[166.11].Q "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 812.4454 2.08 36788 8812 2 812.444656 407.23 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.05 2306.6 - 719372 - - - -0.8899 - 1.632 0.245 - 257.9 1 2 0 -0.0007 7 0 0 0 6.31E+07 3.03E+07 - - - 2.4023 0.9917 230117_WJC_METTL3_WT_vs_EV_F05.08841.08841.2 0.201 12-Jul R.AMIIAER.Q "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 802.4371 2.48 36795 8841 2 802.437763 402.2258 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.05 2310.9 - 901952 - - - 0.815 - 1.494 0.045 - 201.6 1 2 0 0.0007 7 0 0 0 7.58E+07 3.06E+07 - - - 0.6452 0.9733 230117_WJC_METTL3_WT_vs_EV_F05.08876.08876.2 0.697 12-Jun K.LIVDSVK.E sp|O60216|RAD21_HUMAN 1 772.4695 3.64 36800 8876 2 772.469773 387.242 Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2 5.84 2316.7 - 1.16E+06 - - - 0.4117 - 1.39 0.027 - 110.1 6 2 0 0.0003 7 0 0 0 6.04E+07 1.66E+07 - - - -0.0639 0.9937 230117_WJC_METTL3_WT_vs_EV_F05.08877.08877.2 0.735 16-Aug R.NIVEAAAVR[166.11].D "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 951.5377 0.93 36801 8877 2 951.538269 476.7761 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 6 2316.8 - 992141 - - - 0.598 - 0.983 0.258 - 175.6 1 2 0 0.0006 9 0 0 0 1.76E+07 1.89E+07 - - - 0.8968 0.9943 230117_WJC_METTL3_WT_vs_EV_F05.08891.08891.2 0.176 14-Jun K.LVIEEAER.S sp|P50991|TCPD_HUMAN 1 957.5131 16.48 36802 8891 2 957.513736 479.7638 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.25 2319.3 - 155524 - - - 0.6527 - 1.071 0.232 - 128 1 2 0 0.0006 8 0 0 0 9.20E+06 5.58E+05 - - - 0.9612 0.8851 230117_WJC_METTL3_WT_vs_EV_F05.08908.08908.2 17.9 12-Jun K.LIETVVK.Q "sp|Q8TAG9|EXOC6_HUMAN,tr|E7EW84|E7EW84_HUMAN" 2 800.5008 1.86 36806 8908 2 800.500525 401.2577 Exocyst complex component 6 OS=Homo sapiens OX=9606 GN=EXOC6 PE=1 SV=3 6 2321.9 - 353250 - - - -0.2873 - 1.007 0.046 - 89.7 3 2 0 -0.0002 7 0 0 0 1.60E+07 8.60E+06 - - - -0.8103 0.9711 230117_WJC_METTL3_WT_vs_EV_F05.08931.08931.2 3.08 12-Jul K.IIDAALR[166.11].A "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 780.4733 2.26 36808 8931 2 780.47311 391.2439 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2325.8 - 836151 - - - -0.2537 - 1.18 0.073 - 129.5 1 2 0 -0.0002 7 0 0 0 2.14E+09 9.48E+08 - - - 0.1046 0.9887 230117_WJC_METTL3_WT_vs_EV_F05.08936.08936.2 3.3 12-Aug K.IIDAALR.A "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 770.465 2.26 36809 8936 2 770.464199 386.2398 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2326.5 - 1.82E+06 - - - -1.089 - 1.341 0.16 - 204.6 1 2 0 -0.0008 7 0 0 0 2.14E+09 9.48E+08 - - - 1.1522 0.9657 230117_WJC_METTL3_WT_vs_EV_F05.09099.09099.2 0.817 12-May R.LVGEIVR[166.11].R "sp|Q13232|NDK3_HUMAN,sp|Q15021|CND1_HUMAN,sp|Q3MIP1|IPIL2_HUMAN,tr|H3BRA8|H3BRA8_HUMAN,tr|H3BMQ7|H3BMQ7_HUMAN,tr|H3BPD9|H3BPD9_HUMAN,tr|E7EN77|E7EN77_HUMAN" 7 794.489 1.93 36831 9099 2 794.489205 398.2518 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6 2352.6 - 461347 - - - 0.3096 - 1.355 0.045 - 84.7 16 2 0 0.0002 7 0 0 0 7.49E+08 3.88E+08 - - - -0.202 0.8577 230117_WJC_METTL3_WT_vs_EV_F05.09165.09165.2 0.071 14-Sep F.LLAQTTLR[166.11].N "sp|Q8TAV4|STML3_HUMAN,sp|P27105|STOM_HUMAN,tr|F8VSL7|F8VSL7_HUMAN" 3 924.5632 5.07 36842 9165 2 924.56405 463.2889 Stomatin-like protein 3 OS=Homo sapiens OX=9606 GN=STOML3 PE=1 SV=1 9.75 2363.3 - 296928 - - - 0.9345 - 1.44 0.213 - 236.1 1 1 0 0.0009 8 0 0 0 6.63E+07 1.31E+07 - - - 1.7137 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.09230.09230.2 0.0367 14-Jun R.GLDVEDVK.F "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 6 873.4444 1.02 36850 9230 2 873.444755 437.7295 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 2374.1 - 227866 - - - 0.4488 - 1.326 0.262 - 90.7 1 2 0 0.0004 8 0 0 0 1.23E+07 1.21E+07 - - - 1.827 0.8882 230117_WJC_METTL3_WT_vs_EV_F05.09256.09256.2 1.89 14-Apr R.TTC[160.03]FQGVK.V "sp|Q86XD8|ZFAN4_HUMAN,tr|J3KPC0|J3KPC0_HUMAN" 2 939.4484 11.82 36854 9256 2 939.45078 470.7315 AN1-type zinc finger protein 4 OS=Homo sapiens OX=9606 GN=ZFAND4 PE=2 SV=2 7.89 2378.3 - 189017 - - - 2.5313 - 1.04 0.04 - 65 7 2 0 0.0024 8 0 0 0 6.49E+07 5.49E+06 - - - -0.9235 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.09271.09271.2 0.0661 14-Jul K.VIPELNGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 868.5018 3.06 36856 9271 2 868.502661 435.2582 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2380.8 - 1.11E+06 - - - 0.9706 - 1.351 0.378 - 159.3 1 2 0 0.0008 8 0 0 0 9.38E+07 3.06E+07 - - - 2.74 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.09282.09282.2 0.00441 16-Oct R.QTVAVGVIK.N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 913.5597 4.2 36860 9282 2 913.560932 457.7871 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2382.3 - 1.08E+06 - - - 1.3847 - 1.671 0.38 - 405.3 1 2 0 0.0013 9 0 0 0 6.17E+07 1.47E+07 - - - 3.3326 0.999 230117_WJC_METTL3_WT_vs_EV_F05.09294.09294.2 0.00462 16-Sep R.QTVAVGVIK[136.11].N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 921.5739 4.19 36865 9294 2 921.575405 461.7942 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2383.9 - 359299 - - - 1.6689 - 1.318 0.35 - 208.6 1 2 0 0.0015 9 0 0 0 6.17E+07 1.47E+07 - - - 2.4244 0.993 230117_WJC_METTL3_WT_vs_EV_F05.09308.09308.2 0.282 12-Jul K.VITTVLK[136.11].F "sp|Q13439|GOGA4_HUMAN,tr|H0Y6I0|H0Y6I0_HUMAN" 2 780.52 1.83 36866 9308 2 780.521391 391.2673 Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4 PE=1 SV=1 8.72 2386.4 - 499343 - - - 1.7296 - 1.186 0.177 - 151.1 2 2 0 0.0014 7 0 0 0 3.88E+07 2.11E+07 - - - 0.7539 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.09323.09323.2 0.188 14-Aug R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 1.18 36871 9323 2 898.524726 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 2388.5 - 518607 - - - 1.2354 - 1.378 0.373 - 218.3 1 2 0 0.0011 8 0 0 0 6.00E+07 5.10E+07 - - - 2.7626 0.9951 230117_WJC_METTL3_WT_vs_EV_F05.09328.09328.2 0.678 12-Jun K.VVPLYGR.G "sp|Q99942|RNF5_HUMAN,tr|A0A140TA09|A0A140TA09_HUMAN" 2 802.4701 2.2 36872 9328 2 802.472181 402.2423 E3 ubiquitin-protein ligase RNF5 OS=Homo sapiens OX=9606 GN=RNF5 PE=1 SV=1 8.72 2389.3 - 849068 - - - 2.5633 - 1.101 0.259 - 221.5 1 2 0 0.0021 7 0 0 0 7.24E+07 3.29E+07 - - - 1.2582 0.9912 230117_WJC_METTL3_WT_vs_EV_F05.09344.09344.2 2.74 14-Jun R.LVGDVIQR[166.11].F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 908.5319 1.24 36875 9344 2 908.533397 455.2732 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 2391.9 - 1.04E+06 - - - 1.6631 - 1.202 0.162 - 92.3 3 2 0 0.0015 8 0 0 0 5.65E+07 4.56E+07 - - - 0.5788 0.9651 230117_WJC_METTL3_WT_vs_EV_F05.09404.09404.2 0.00204 14-Sep R.YPDGIISK.P sp|Q86U44|MTA70_HUMAN 1 891.4702 113.45 36890 9404 2 891.471913 446.7424 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2401 - 1.40E+06 - - - 1.9406 - 1.705 0.385 - 233.8 1 1 0 0.0017 8 0 0 0 3.88E+08 3.42E+06 - - - 3.4933 0.9947 230117_WJC_METTL3_WT_vs_EV_F05.09464.09464.2 0.55 12-Jul K.LLEQALK.T sp|Q99543|DNJC2_HUMAN 1 813.496 1.27 36898 9464 2 813.495796 407.7553 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 6 2410.8 - 259957 - - - -0.2557 - 1.503 0.137 - 128.3 1 2 0 -0.0002 7 0 0 0 1.10E+07 8.67E+06 - - - 1.3439 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.09494.09494.2 0.00199 18-Aug R.GYSFTTTAER.E "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1131.5197 1.31 36904 9494 2 1131.520231 566.7671 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 2415.6 - 127147 - - - 0.5108 - 1.534 0.397 - 268.1 1 2 0 0.0006 10 0 0 0 5.81E+06 4.43E+06 - - - 3.1674 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.09497.09497.2 0.0679 14-Aug R.LVTTGVLK.Q sp|P07305|H10_HUMAN 1 829.5273 1.06 36905 9497 2 829.527551 415.7709 Histone H1.0 OS=Homo sapiens OX=9606 GN=H1-0 PE=1 SV=3 8.75 2416 - 534890 - - - 0.2978 - 1.693 0.246 - 240.4 1 2 0 0.0002 8 0 0 0 2.23E+07 2.10E+07 - - - 2.4458 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.09501.09501.2 0.468 18-May R.GYSFTTTAER[166.11].E "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1141.5279 1.31 36909 9501 2 1141.527537 571.7712 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 2416.5 - 106236 - - - -0.3381 - 1.096 0.302 - 44.7 1 2 0 -0.0004 10 0 0 0 5.79E+06 4.43E+06 - - - 1.5273 0.999 230117_WJC_METTL3_WT_vs_EV_F05.09505.09505.2 0.00237 18-Aug K.FADLSEAANR.N "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1092.52 1.48 36910 9505 2 1092.519252 547.2673 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 2417.1 - 151324 - - - -0.6728 - 1.656 0.39 - 200.6 1 2 0 -0.0007 10 0 0 0 2.45E+07 1.66E+07 - - - 3.3293 0.9882 230117_WJC_METTL3_WT_vs_EV_F05.09522.09522.2 2.08 12-Aug R.LGLVDTR.Q sp|Q6P4I2|WDR73_HUMAN 1 772.4443 8.14 36913 9522 2 772.446572 387.2294 WD repeat-containing protein 73 OS=Homo sapiens OX=9606 GN=WDR73 PE=1 SV=1 5.84 2419.8 - 1.25E+06 - - - 2.9374 - 1.353 0.103 - 150.5 1 2 0 0.0023 7 0 0 0 1.30E+07 1.59E+06 - - - 0.759 0.9263 230117_WJC_METTL3_WT_vs_EV_F05.09549.09549.2 4.69 12-May K.LLPYAER[166.11].L "sp|Q14997|PSME4_HUMAN,tr|F8WBH5|F8WBH5_HUMAN" 2 870.4839 1.57 36918 9549 2 870.484366 436.2492 Proteasome activator complex subunit 4 OS=Homo sapiens OX=9606 GN=PSME4 PE=1 SV=2 6 2424.1 - 114551 - - - 0.5664 - 0.926 0.059 - 74.1 1 2 0 0.0005 7 0 0 0 8.79E+06 5.61E+06 - - - -0.767 0.9837 230117_WJC_METTL3_WT_vs_EV_F05.09562.09562.2 0.153 16-May R.QAVDVSPLR[166.11].R "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 993.5483 0.77 36924 9562 2 993.54997 497.7814 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 5.84 2425.8 - 54922.7 - - - 1.7171 - 0.998 0.152 - 55.6 1 2 0 0.0017 9 0 0 0 3.64E+06 4.74E+06 - - - 0.1573 0.9838 230117_WJC_METTL3_WT_vs_EV_F05.09614.09614.2 1.07 12-Jun K.LEPVPLK.G "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN" 2 794.4902 2.57 36935 9614 2 794.490092 398.2524 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6 2433.9 - 578996 - - - -0.1246 - 1.247 0.096 - 148.6 1 2 0 -0.0001 7 0 0 0 5.68E+07 2.21E+07 - - - 0.4495 0.9935 230117_WJC_METTL3_WT_vs_EV_F05.09624.09624.2 8.03 14-Jun R.LLTGPVVR.G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 853.5385 2.38 36936 9624 2 853.539013 427.7765 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2435.6 - 467522 - - - 0.5565 - 1.37 0.12 - 98 1 2 0 0.0005 8 0 0 0 3.64E+07 1.53E+07 - - - 0.8766 0.9664 230117_WJC_METTL3_WT_vs_EV_F05.09625.09625.2 7.26 14-May R.LLTGPVVR[166.11].G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 863.5468 2.38 36937 9625 2 863.547074 432.7807 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2435.7 - 201338 - - - 0.308 - 1.104 0.111 - 32.2 6 2 0 0.0003 8 0 0 0 3.64E+07 1.53E+07 - - - -0.1884 0.9823 230117_WJC_METTL3_WT_vs_EV_F05.09634.09634.2 0.426 12-Jun K.LEPVPLK[136.11].G "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN" 2 802.5044 2.53 36938 9634 2 802.505316 402.2595 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6 2437.2 - 667021 - - - 1.1526 - 1.251 0.082 - 152.9 4 2 0 0.0009 7 0 0 0 5.60E+07 2.21E+07 - - - 0.087 0.9753 230117_WJC_METTL3_WT_vs_EV_F05.09639.09639.2 3.78 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 104.62 36939 9639 2 841.502636 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 2437.9 - 5.32E+06 - - - 0.5752 - 1.335 0.023 - 201 2 2 0 0.0005 8 0 0 0 6.90E+08 6.60E+06 - - - -0.0523 0.985 230117_WJC_METTL3_WT_vs_EV_F05.09649.09649.2 0.935 12-Jun R.ILVDVEK.V sp|P11216|PYGB_HUMAN 1 814.48 0.27 36942 9649 2 814.47966 408.2473 "Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB PE=1 SV=5" 4.37 2439.4 - 586379 - - - -0.442 - 1.33 0.094 - 106.4 1 2 0 -0.0004 7 0 0 0 1.20E+07 4.44E+07 - - - 0.6388 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.09650.09650.3 0.00268 Dec-40 R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 1.03 36943 9650 3 1240.609448 414.5431 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2439.6 - 316244 - - - 1.5138 - 1.926 0.385 - 133.4 1 2 0 0.0019 11 0 0 0 2.03E+07 1.97E+07 - - - 4.6939 0.9781 230117_WJC_METTL3_WT_vs_EV_F05.09700.09700.2 0.0226 12-Jun R.VLSSLVR.D sp|Q969H6|POP5_HUMAN 1 772.4807 1.64 36952 9700 2 772.481696 387.2476 Ribonuclease P\MRP protein subunit POP5 OS=Homo sapiens OX=9606 GN=POP5 PE=1 SV=1 9.72 2447.6 - 539899 - - - 1.3036 - 1.288 0.013 - 161 1 2 0 0.001 7 0 0 0 4.20E+07 2.56E+07 - - - -0.0614 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.09714.09714.2 0.0773 22-Aug R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 999 36955 9714 2 1380.644862 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2449.7 - 69821.3 - - - 2.8769 - 1.592 0.244 - 178.6 1 2 0 0.004 12 0 0 0 6.69E+06 0.00E+00 - - - 2.0654 0.9907 230117_WJC_METTL3_WT_vs_EV_F05.09716.09716.2 0.0763 12-Aug R.LGPETFR[166.11].Q sp|P57086|SCND1_HUMAN 1 828.4369 1.78 36956 9716 2 828.439515 415.2257 SCAN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCAND1 PE=1 SV=1 6 2450 - 165621 - - - 3.1288 - 1.369 0.133 - 153.6 1 2 0 0.0026 7 0 0 0 3.64E+07 2.04E+07 - - - 1.0177 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.09732.09732.2 0.0624 16-Aug K.IVVVTAGVR[166.11].Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 922.5839 0.83 36961 9732 2 922.584534 462.2992 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2452.3 - 578238 - - - 0.6634 - 1.634 0.162 - 227.3 1 2 0 0.0006 9 0 0 0 1.35E+08 1.63E+08 - - - 1.6579 0.9468 230117_WJC_METTL3_WT_vs_EV_F05.09747.09747.2 1.17 14-Jun R.ILADEALK.L sp|Q08426|ECHP_HUMAN 1 871.5015 1.15 36964 9747 2 871.50247 436.758 Peroxisomal bifunctional enzyme OS=Homo sapiens OX=9606 GN=EHHADH PE=1 SV=3 4.37 2454.6 - 276476 - - - 1.1314 - 1.026 0.052 - 60.4 2 2 0 0.001 8 0 0 0 7.41E+06 6.46E+06 - - - -0.6323 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.09749.09749.2 0.0986 16-Jul K.IVVVTAGVR.Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 912.5757 0.82 36965 9749 2 912.576481 457.2951 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2454.9 - 1.57E+06 - - - 0.9084 - 1.602 0.254 - 170.5 1 2 0 0.0008 9 0 0 0 1.34E+08 1.63E+08 - - - 2.2801 0.8982 230117_WJC_METTL3_WT_vs_EV_F05.09759.09759.2 0.652 12-Aug N.LNTLIQR[166.11].S "sp|P20036|DPA1_HUMAN,sp|Q00839|HNRPU_HUMAN,sp|Q8IUG5|MY18B_HUMAN,tr|A0A140T914|A0A140T914_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|F5H6I8|F5H6I8_HUMAN,tr|A0A140T9R4|A0A140T9R4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A140T9D6|A0A140T9D6_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A140T9Y9|A0A140T9Y9_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A140T9H1|A0A140T9H1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A140T9U4|A0A140T9U4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A140T9F8|A0A140T9F8_HUMAN,tr|J3KQ99|J3KQ99_HUMAN" 24 866.5213 0.55 36969 9759 2 866.522421 434.2679 "HLA class II histocompatibility antigen, DP alpha 1 chain OS=Homo sapiens OX=9606 GN=HLA-DPA1 PE=1 SV=1" 9.75 2456.2 - 2.51E+06 - - - 1.2694 - 1.888 0.132 - 281.8 1 1 0 0.0011 7 0 0 0 9.26E+07 1.68E+08 - - - 2.0293 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.09776.09776.2 0.0951 18-Sep K.IGAVEEELNR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1138.5858 0.82 36975 9776 2 1138.588046 570.3002 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.25 2458.7 - 110106 - - - 1.9972 - 1.74 0.219 - 228.2 1 2 0 0.0023 10 0 0 0 6.13E+06 7.49E+06 - - - 2.2039 0.9952 230117_WJC_METTL3_WT_vs_EV_F05.09787.09787.2 4.49 12-Jun K.ILLSPER.V "sp|P24928|RPB1_HUMAN,tr|H3BVE3|H3BVE3_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 3 826.4913 0.97 36977 9787 2 826.491964 414.2529 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 6 2460.4 - 743942 - - - 0.8603 - 1.316 0.153 - 131.4 1 2 0 0.0007 7 0 0 0 8.71E+07 9.00E+07 - - - 1.0409 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.09816.09816.2 0.0267 18-Jul K.MLVSGAGDIK.L "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 989.5216 33.79 36984 9816 2 989.521065 495.7681 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.59 2464.7 - 249648 - - - -0.5073 - 1.44 0.356 - 111.9 1 2 0 -0.0005 10 0 0 0 1.33E+07 3.94E+05 - - - 2.6881 0.9945 230117_WJC_METTL3_WT_vs_EV_F05.09848.09848.2 0.218 12-Jul R.MIVGTLK.G "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 760.4517 2.76 36985 9848 2 760.45224 381.2331 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 8.5 2470.5 - 689519 - - - 0.714 - 1.251 0.164 - 209.3 1 2 0 0.0005 7 0 0 0 3.33E+08 1.21E+08 - - - 0.9617 0.9917 230117_WJC_METTL3_WT_vs_EV_F05.09859.09859.2 0.13 12-Aug R.MIVGTLK[136.11].G "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 768.4659 2.77 36988 9859 2 768.465598 385.2402 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 8.5 2472 - 999942 - - - -0.3891 - 1.314 0.155 - 223.7 1 2 0 -0.0003 7 0 0 0 3.32E+08 1.20E+08 - - - 1.051 0.9908 230117_WJC_METTL3_WT_vs_EV_F05.09866.09866.2 0.743 12-Jul R.ILLEAAR[166.11].L "sp|P49189|AL9A1_HUMAN,sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 3 794.489 1.99 36992 9866 2 794.48826 398.2518 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3 6 2472.9 - 478335 - - - -0.8798 - 1.427 0.141 - 171.1 1 2 0 -0.0007 7 0 0 0 6.25E+07 3.14E+07 - - - 1.2089 0.9612 230117_WJC_METTL3_WT_vs_EV_F05.09883.09883.2 12.4 12-May R.ILLEAAR.L "sp|P49189|AL9A1_HUMAN,sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 3 784.4807 2.01 36997 9883 2 784.480928 393.2476 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3 6 2475.4 - 1.51E+06 - - - 0.3047 - 1.24 0.057 - 61.6 9 2 0 0.0002 7 0 0 0 6.38E+07 3.17E+07 - - - -0.2827 1 230117_WJC_METTL3_WT_vs_EV_F05.09962.09962.2 4.43E-08 22-Dec R.AQVQEFC[160.03]DYGTK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1444.6293 8.99 37010 9962 2 1444.630842 723.3219 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2487.9 - 392905 - - - 1.0812 - 2.197 0.643 - 463.6 1 2 0 0.0016 12 0 0 0 2.50E+07 2.78E+06 - - - 5.8607 0.8816 230117_WJC_METTL3_WT_vs_EV_F05.09969.09969.2 5.9 14-May R.VMGLVPAK.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 813.4782 1.57 37012 9969 2 813.479019 407.7464 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.72 2488.9 - 147196 - - - 0.9502 - 0.924 0.043 - 77.2 4 2 0 0.0008 8 0 0 0 3.71E+07 2.37E+07 - - - -1.149 0.9947 230117_WJC_METTL3_WT_vs_EV_F05.09990.09990.2 1.23 14-Aug R.VMGLVPAK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 821.4924 1.7 37018 9990 2 821.494194 411.7535 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.72 2491.9 - 360433 - - - 2.1278 - 1.136 0.22 - 170 1 2 0 0.0017 8 0 0 0 3.70E+07 2.18E+07 - - - 1.0499 0.8513 230117_WJC_METTL3_WT_vs_EV_F05.09994.09994.2 7.66 12-May R.IILPPEK.E sp|P49411|EFTU_HUMAN 1 808.5058 4.22 37019 9994 2 808.505727 405.2602 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6 2492.5 - 298918 - - - -0.141 - 1.049 0.015 - 76.3 6 2 0 -0.0001 7 0 0 0 6.79E+07 1.61E+07 - - - -1.0443 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.10010.10010.2 0.0262 12-Jun R.LMDVMAK.E sp|Q12874|SF3A3_HUMAN 1 806.403 3.22 37024 10010 2 806.405343 404.2088 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2494.9 - 447800 - - - 2.8658 - 1.29 0.249 - 109 1 2 0 0.0023 7 0 0 0 1.15E+08 3.56E+07 - - - 1.6862 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.10026.10026.2 0.0384 12-Jun R.LMDVMAK[136.11].E sp|Q12874|SF3A3_HUMAN 1 814.4172 3.22 37025 10026 2 814.417925 408.2159 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2497.7 - 612952 - - - 0.8509 - 1.193 0.314 - 84.8 1 2 0 0.0007 7 0 0 0 1.14E+08 3.54E+07 - - - 1.9191 0.959 230117_WJC_METTL3_WT_vs_EV_F05.10057.10057.2 4.51 12-Jun -.MAAPILR.S sp|Q9Y2Z4|SYYM_HUMAN 1 770.4473 4.11 37031 10057 2 770.446836 386.2309 "Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2" 9.5 2502.9 - 1.67E+06 - - - -0.5763 - 1.209 0.09 - 117.5 5 2 0 -0.0004 7 0 0 0 1.35E+08 3.28E+07 - - - -0.0053 0.9863 230117_WJC_METTL3_WT_vs_EV_F05.10084.10084.2 5.11 14-Jun R.IIAEALTR[166.11].V "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 5 895.5366 0.99 37034 10084 2 895.538371 448.7756 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 2507.6 - 725666 - - - 1.9363 - 1.2 0.098 - 103.2 1 2 0 0.0017 8 0 0 0 4.97E+07 5.05E+07 - - - 0.3142 0.8804 230117_WJC_METTL3_WT_vs_EV_F05.10116.10116.2 0.308 12-Jun N.VDEFVK[136.11]R.L sp|Q9NVH2|INT7_HUMAN 1 899.4956 - 37038 10116 2 899.497427 450.7551 Integrator complex subunit 7 OS=Homo sapiens OX=9606 GN=INTS7 PE=1 SV=1 6.04 2513 - 869116 - - - 2.0122 - 1.388 0.255 - 96.4 1 1 0 0.0018 7 0 0 0 - - - - - 1.9627 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.10121.10121.2 0.191 16-Jul K.VELQELNDR.F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1114.5619 3.35 37039 10121 2 1114.565512 558.2882 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.14 2513.8 - 197018 - - - 3.2838 - 1.677 0.248 - 219.6 1 2 0 0.0037 9 0 0 0 2.34E+07 6.98E+06 - - - 2.3673 0.9876 230117_WJC_METTL3_WT_vs_EV_F05.10135.10135.2 0.505 12-May R.VLYSLAK[136.11].K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 800.4887 1.39 37041 10135 2 800.489012 401.2516 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.56 2516 - 467544 - - - 0.3385 - 1.289 0.114 - 99.6 3 2 0 0.0003 7 0 0 0 6.33E+07 4.54E+07 - - - 0.4742 0.9533 230117_WJC_METTL3_WT_vs_EV_F05.10140.10140.2 4.07 12-Jun R.VLYSLAK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 792.4745 1.41 37042 10140 2 792.47441 397.2445 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.56 2516.8 - 690239 - - - -0.1653 - 1.105 0.053 - 121.9 1 2 0 -0.0001 7 0 0 0 6.38E+07 4.54E+07 - - - -0.2512 0.9898 230117_WJC_METTL3_WT_vs_EV_F05.10191.10191.2 3.3 12-Aug R.LYTVVPR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 846.4963 1.54 37051 10191 2 846.497229 424.2554 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 2524.7 - 1.32E+06 - - - 1.0514 - 1.133 0.14 - 248.3 1 2 0 0.0009 7 0 0 0 1.57E+08 1.02E+08 - - - 0.4704 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.10222.10222.2 0.00357 12-Jul R.LYTVVPR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 856.5046 1.54 37056 10222 2 856.506412 429.2596 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 2529.7 - 1.57E+06 - - - 2.1051 - 1.365 0.302 - 205.2 1 2 0 0.0018 7 0 0 0 1.57E+08 1.02E+08 - - - 2.2569 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.10227.10227.2 0.0163 14-Sep K.IPAMTIAK[136.11].N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.503 2.17 37058 10227 2 851.504432 426.7588 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2530.3 - 1.42E+06 - - - 1.67 - 1.618 0.271 - 214.4 1 2 0 0.0014 8 0 0 0 2.03E+09 9.37E+08 - - - 2.4934 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.10230.10230.2 0.0908 14-Aug K.IPAMTIAK.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.4888 2.17 37059 10230 2 843.489827 422.7517 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2530.7 - 3.08E+06 - - - 1.2057 - 1.276 0.297 - 173.2 1 2 0 0.001 8 0 0 0 2.03E+09 9.37E+08 - - - 1.9694 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.10252.10252.2 0.000775 16-Aug R.VLPVYGGPK.G "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 928.5382 1.77 37064 10252 2 928.538987 465.2764 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 8.56 2534.1 - 148238 - - - 0.8443 - 1.451 0.448 - 176.3 1 2 0 0.0008 9 0 0 0 1.92E+07 1.09E+07 - - - 3.4266 0.9752 230117_WJC_METTL3_WT_vs_EV_F05.10295.10295.2 0.655 12-Jun R.VAPVLIR.E "sp|P30419|NMT1_HUMAN,sp|O60551|NMT2_HUMAN,tr|A0A7I2V3X4|A0A7I2V3X4_HUMAN,tr|A0A7I2V539|A0A7I2V539_HUMAN,tr|Q5VUC6|Q5VUC6_HUMAN,tr|A0A7I2V3U5|A0A7I2V3U5_HUMAN" 6 766.5065 0.87 37073 10295 2 766.505192 384.2605 Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2 9.72 2540.5 - 1.14E+06 - - - -1.7182 - 1.221 0.16 - 187.4 1 2 0 -0.0013 7 0 0 0 3.19E+07 3.65E+07 - - - 0.855 0.9828 230117_WJC_METTL3_WT_vs_EV_F05.10297.10297.2 0.706 14-Jul R.LLTGPVVR[166.11].G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 863.5468 2.25 37074 10297 2 863.545553 432.7807 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2540.7 - 2.61E+06 - - - -1.4533 - 1.392 0.131 - 129.3 1 2 0 -0.0013 8 0 0 0 3.04E+08 1.35E+08 - - - 1.0057 0.969 230117_WJC_METTL3_WT_vs_EV_F05.10354.10354.2 0.0984 16-Sep K.LSDGVAVLK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 908.5422 2.79 37076 10354 2 908.537063 455.2784 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2550.4 - 2.28E+06 - - - -5.6904 - 1.938 0.269 - 140.8 1 2 0 -0.0052 9 0 0 0 2.19E+08 7.85E+07 - - - 2.9404 0.9459 230117_WJC_METTL3_WT_vs_EV_F05.10388.10388.2 1.92 12-Jun K.VITVLTR.S sp|Q14680|MELK_HUMAN 1 800.512 2.13 37078 10388 2 800.51095 401.2633 Maternal embryonic leucine zipper kinase OS=Homo sapiens OX=9606 GN=MELK PE=1 SV=3 9.72 2556 - 0 - - - -1.2979 - 1.375 0.075 - 99.6 13 2 0 -0.001 7 0 0 0 2.16E+07 1.01E+07 - - - 0.1061 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.10400.10400.2 0.000264 12-Jul R.LVDMMER.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 892.4147 1.21 37079 10400 2 892.412691 447.2146 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 2558 - 1.83E+06 - - - -2.2053 - 1.28 0.48 - 174.1 1 2 0 -0.002 7 0 0 0 1.76E+08 1.45E+08 - - - 3.3679 0.9926 230117_WJC_METTL3_WT_vs_EV_F05.10466.10466.2 0.299 12-Jun K.FIGELGK.L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 762.4276 2.23 37085 10466 2 762.427065 382.2211 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2568.7 - 1.57E+06 - - - -0.6886 - 1.402 0.16 - 151.1 1 2 0 -0.0005 7 0 0 0 2.44E+08 1.09E+08 - - - 1.2932 0.9829 230117_WJC_METTL3_WT_vs_EV_F05.10470.10470.2 0.204 14-Aug R.VVLLAEGR.L sp|O43865|SAHH2_HUMAN 1 855.5178 3.21 37086 10470 2 855.515047 428.7662 S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1 PE=1 SV=2 5.97 2569.3 - 1.18E+06 - - - -3.2203 - 1.229 0.308 - 216.2 1 2 0 -0.0028 8 0 0 0 4.23E+07 1.32E+07 - - - 1.9369 0.9818 230117_WJC_METTL3_WT_vs_EV_F05.10486.10486.2 0.0341 12-Jul K.FIGELGK[136.11].L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 770.4418 2.18 37089 10486 2 770.438793 386.2282 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2571.7 - 1.90E+06 - - - -3.89 - 1.436 0.284 - 181.5 1 2 0 -0.003 7 0 0 0 2.39E+08 1.09E+08 - - - 2.2843 0.9925 230117_WJC_METTL3_WT_vs_EV_F05.10520.10520.2 0.0109 14-Aug R.LGPLQVAR.V sp|P38117|ETFB_HUMAN 1 852.5181 3.18 37093 10520 2 852.515662 427.2663 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 9.75 2577.1 - 4.31E+06 - - - -2.9032 - 1.663 0.272 - 252.9 1 2 0 -0.0025 8 0 0 0 2.54E+08 7.98E+07 - - - 2.5832 0.9449 230117_WJC_METTL3_WT_vs_EV_F05.10529.10529.2 0.908 12-May R.LVNIVPK[136.11].K "sp|Q8NEY8|PPHLN_HUMAN,tr|F8VRK2|F8VRK2_HUMAN,tr|F8VWU8|F8VWU8_HUMAN,tr|F8VXV7|F8VXV7_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8VPY7|F8VPY7_HUMAN" 6 789.5204 0.84 37095 10529 2 789.519544 395.7675 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 8.75 2578.4 - 3.39E+06 - - - -1.0525 - 1.341 0.039 - 63.9 4 2 0 -0.0008 7 0 0 0 1.87E+08 2.21E+08 - - - -0.0104 0.849 230117_WJC_METTL3_WT_vs_EV_F05.10538.10538.2 0.0157 12-Jul R.VVDLMAH.M "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 783.3949 - 37096 10538 2 783.393169 392.7047 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.08 2579.8 - 4.01E+06 - - - -2.2224 - 1.528 0.444 - 170.6 1 1 0 -0.0017 7 0 0 0 - - - - - 3.6632 0.992 230117_WJC_METTL3_WT_vs_EV_F05.10540.10540.2 1.19 12-Jun K.AIFAGYK.R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 768.417 0.79 37097 10540 2 768.41676 385.2158 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2580 - 1.30E+06 - - - -0.3462 - 1.162 0.209 - 125.6 1 2 0 -0.0003 7 0 0 0 2.41E+08 3.07E+08 - - - 1.0603 0.9944 230117_WJC_METTL3_WT_vs_EV_F05.10554.10554.2 0.216 12-Jun K.AIFAGYK[136.11].R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 776.4312 0.77 37101 10554 2 776.431216 389.2229 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2582 - 3.46E+06 - - - -0.0129 - 1.235 0.2 - 158.4 1 2 0 0 7 0 0 0 2.41E+08 3.13E+08 - - - 1.187 0.917 230117_WJC_METTL3_WT_vs_EV_F05.10561.10561.2 0.761 14-Jun K.SVLAGPLR[166.11].T sp|Q9UBZ4|APEX2_HUMAN 1 821.4999 1.01 37103 10561 2 821.495865 411.7572 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 9.47 2583 - 569665 - - - -4.8606 - 1.392 0.184 - 142.2 1 2 0 -0.004 8 0 0 0 3.23E+07 3.20E+07 - - - 1.3963 0.9473 230117_WJC_METTL3_WT_vs_EV_F05.10570.10570.2 1.32 12-May R.LPPDVLR[166.11].W sp|P78527|PRKDC_HUMAN 1 818.489 5.49 37105 10570 2 818.48926 410.2518 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2584.3 - 514227 - - - 0.3678 - 1.134 0.081 - 56.6 16 2 0 0.0003 7 0 0 0 5.55E+08 1.01E+08 - - - -0.5003 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.10582.10582.2 2.53 12-Jun R.FLAPYGR.Q "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 822.4388 0.33 37106 10582 2 822.439599 412.2267 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 8.75 2586.3 - 771387 - - - 0.9423 - 1.134 0.256 - 167.1 1 2 0 0.0008 7 0 0 0 5.43E+07 1.66E+08 - - - 1.33 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.10584.10584.2 0.314 18-Jul K.LLVATSVAAR.G "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 999.6077 5.61 37107 10584 2 999.6092 500.8111 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 9.75 2586.5 - 605954 - - - 1.5206 - 1.231 0.246 - 162.2 1 2 0 0.0015 10 0 0 0 4.45E+07 7.92E+06 - - - 1.4376 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.10590.10590.2 0.00279 16-Oct R.QEYEQLIAK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1120.5764 0.58 37108 10590 2 1120.576664 561.2955 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.53 2587.4 - 247243 - - - 0.1999 - 1.891 0.437 - 406.7 1 2 0 0.0002 9 0 0 0 1.49E+07 2.59E+07 - - - 4.1118 0.9781 230117_WJC_METTL3_WT_vs_EV_F05.10606.10606.2 0.868 12-May K.VLLAEYK.N sp|Q16513|PKN2_HUMAN 1 834.4851 0 37110 10606 2 834.485078 418.2498 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 5.97 2590 - 1.23E+06 - - - -0.0324 - 1.18 0.087 - 83.3 1 2 0 0 7 0 0 0 6.11E+07 2.33E+10 - - - 0.208 0.9949 230117_WJC_METTL3_WT_vs_EV_F05.10607.10607.2 0.162 12-Aug R.FLAPYGR[166.11].Q "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 832.4471 0.29 37111 10607 2 832.447316 417.2308 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 8.75 2590.1 - 1.27E+06 - - - 0.2667 - 1.257 0.187 - 231 1 2 0 0.0002 7 0 0 0 6.17E+07 2.12E+08 - - - 1.1468 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.10610.10610.2 0.0324 14-May K.YVPLADVK[136.11].S "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 911.5208 0.57 37112 10610 2 911.522102 456.7677 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.83 2590.5 - 755993 - - - 1.4624 - 1.16 0.273 - 98.8 1 2 0 0.0013 8 0 0 0 4.05E+07 7.07E+07 - - - 1.5046 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.10612.10612.2 0.262 12-Jul R.LPPDVLR.W sp|P78527|PRKDC_HUMAN 1 808.4807 10.49 37113 10612 2 808.481573 405.2476 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2590.7 - 1.00E+06 - - - 1.0934 - 1.403 0.178 - 197.3 1 2 0 0.0009 7 0 0 0 1.12E+09 1.06E+08 - - - 1.4283 0.9046 230117_WJC_METTL3_WT_vs_EV_F05.10615.10615.2 5.98 12-Jun K.VPLGTFR.K sp|Q9Y6X9|MORC2_HUMAN 1 788.4545 1.11 37115 10615 2 788.455181 395.2345 ATPase MORC2 OS=Homo sapiens OX=9606 GN=MORC2 PE=1 SV=2 9.72 2591 - 1.20E+06 - - - 0.8967 - 0.964 0.029 - 108.1 2 2 0 0.0007 7 0 0 0 3.37E+07 3.04E+07 - - - -0.9957 0.9949 230117_WJC_METTL3_WT_vs_EV_F05.10618.10618.2 0.955 12-Jul R.VLISSLK.D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 758.4902 0.77 37116 10618 2 758.491396 380.2524 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2591.4 - 417150 - - - 1.5887 - 1.483 0.093 - 141.4 1 2 0 0.0012 7 0 0 0 9.98E+07 1.30E+08 - - - 0.9761 0.9931 230117_WJC_METTL3_WT_vs_EV_F05.10629.10629.2 2.63 12-Jul R.VLISSLK[136.11].D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 766.5044 1.22 37120 10629 2 766.505219 384.2595 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2592.9 - 844898 - - - 1.0802 - 1.243 0.138 - 178.9 1 2 0 0.0008 7 0 0 0 9.82E+07 8.06E+07 - - - 0.7493 0.9822 230117_WJC_METTL3_WT_vs_EV_F05.10635.10635.2 1.57 12-May K.SVLTPLR[166.11].G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 794.489 1.25 37123 10635 2 794.49023 398.2518 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2593.6 - 560024 - - - 1.5998 - 1.137 0.087 - 84.3 1 2 0 0.0013 7 0 0 0 5.50E+07 4.42E+07 - - - 0.09 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.10658.10658.2 0.00693 12-Jul K.SVLTPLR.G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 784.4807 1.23 37130 10658 2 784.481916 393.2476 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2596.9 - 1.07E+06 - - - 1.5641 - 1.377 0.164 - 192.8 1 2 0 0.0012 7 0 0 0 5.72E+07 4.64E+07 - - - 1.2656 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.10672.10672.2 0.473 12-May R.LLDVYEK.E "sp|Q96EF6|FBX17_HUMAN,tr|M0R2C6|M0R2C6_HUMAN,tr|M0QZ95|M0QZ95_HUMAN" 3 878.4749 1.23 37136 10672 2 878.47615 440.2447 F-box only protein 17 OS=Homo sapiens OX=9606 GN=FBXO17 PE=1 SV=1 4.37 2598.7 - 391188 - - - 1.3842 - 1.267 0.172 - 59 1 2 0 0.0012 7 0 0 0 1.06E+07 8.64E+06 - - - 1.0609 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.10682.10682.2 1.85 12-Aug R.IVEGILK.R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 770.4902 2.06 37138 10682 2 770.491571 386.2524 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 2600.3 - 1.46E+06 - - - 1.7911 - 1.582 0.097 - 167.9 1 2 0 0.0014 7 0 0 0 6.51E+08 3.16E+08 - - - 1.2104 0.9912 230117_WJC_METTL3_WT_vs_EV_F05.10685.10685.2 5.96 12-May R.IVEGILK[136.11].R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 778.5044 2.06 37139 10685 2 778.505471 390.2595 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 2600.7 - 1.07E+06 - - - 1.3873 - 1.315 0.139 - 47.9 7 2 0 0.0011 7 0 0 0 6.51E+08 3.16E+08 - - - 0.5575 0.9579 230117_WJC_METTL3_WT_vs_EV_F05.10686.10686.2 1.01 14-Jul R.ILLAVNGK[136.11].V sp|O15173|PGRC2_HUMAN 1 834.5418 1.99 37140 10686 2 834.543484 418.2782 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.75 2600.8 - 170492 - - - 1.9711 - 1.171 0.008 - 88.8 1 2 0 0.0016 8 0 0 0 4.74E+07 2.38E+07 - - - -0.4243 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.10687.10687.2 1.01E-05 26-Jul R.SLYASSPGGVYATR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1427.7045 2.03 37141 10687 2 1427.709326 714.8595 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2601 - 106081 - - - 3.3845 - 1.735 0.51 - 130 1 2 0 0.0048 14 0 0 0 7.89E+06 3.88E+06 - - - 4.1891 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.10697.10697.2 0.0843 12-Aug K.MGITPLR.N "sp|Q12789|TF3C1_HUMAN,sp|O43325|LYRM1_HUMAN,tr|H3BNA8|H3BNA8_HUMAN" 3 786.4422 1.19 37144 10697 2 786.442848 394.2284 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 9.5 2602.4 - 680633 - - - 0.8303 - 1.751 0.273 - 235.3 1 2 0 0.0007 7 0 0 0 5.28E+07 4.44E+07 - - - 2.8322 0.998 230117_WJC_METTL3_WT_vs_EV_F05.10707.10707.2 0.0222 18-Jul R.IITEGFEAAK.E sp|P40227|TCPZ_HUMAN 1 1077.5706 12.6 37146 10707 2 1077.573714 539.7926 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 2603.9 - 437202 - - - 2.8657 - 1.312 0.325 - 100.4 1 2 0 0.0031 10 0 0 0 3.37E+07 2.67E+06 - - - 2.1985 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.10722.10722.2 0.49 12-Aug K.LTGMAFR.V "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 794.4109 2.76 37154 10722 2 794.412391 398.2127 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 9.75 2605.9 - 1.77E+06 - - - 1.8844 - 1.828 0.307 - 213.7 1 2 0 0.0015 7 0 0 0 1.19E+10 4.30E+09 - - - 3.2194 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.10731.10731.2 0.0139 14-Jun R.VIQALAMK.G "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 872.5154 1.17 37155 10731 2 872.516745 437.265 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.72 2607.4 - 275636 - - - 1.5874 - 1.353 0.283 - 95 1 2 0 0.0014 8 0 0 0 2.12E+07 1.81E+07 - - - 2.0426 0.9423 230117_WJC_METTL3_WT_vs_EV_F05.10732.10732.2 1.5 12-Jun R.VLC[160.03]PVLR[166.11].R "sp|Q8WY41|NANO1_HUMAN,tr|Q5T9H5|Q5T9H5_HUMAN" 2 865.5083 13.28 37156 10732 2 865.506548 433.7614 Nanos homolog 1 OS=Homo sapiens OX=9606 GN=NANOS1 PE=1 SV=2 8.22 2607.5 - 232115 - - - -2.0404 - 1.194 0.105 - 96.5 1 2 0 -0.0018 7 0 0 0 1.44E+08 1.08E+07 - - - 0.3778 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.10762.10762.2 0.389 12-Aug R.MGLVMDR[166.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 830.4018 2.18 37170 10762 2 830.401712 416.2082 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2611.7 - 743774 - - - -0.106 - 1.609 0.27 - 263.2 1 2 0 -0.0001 7 0 0 0 1.25E+09 5.74E+08 - - - 2.5422 0.9877 230117_WJC_METTL3_WT_vs_EV_F05.10768.10768.2 14.5 12-Jul R.LIITQVR.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 841.5385 1 37171 10768 2 841.538729 421.7765 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 9.75 2612.6 - 7.60E+06 - - - 0.227 - 1.407 0.053 - 179.3 1 2 0 0.0002 7 0 0 0 4.03E+08 4.03E+08 - - - 0.5143 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.10769.10769.2 0.154 16-Sep K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 0.79 37172 10769 2 993.584823 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2612.8 - 266538 - - - 0.1741 - 1.602 0.259 - 223.3 1 2 0 0.0002 9 0 0 0 7.20E+07 9.14E+07 - - - 2.3173 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.10777.10777.2 0.00204 12-Jul R.MGLVMDR.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 820.3935 2.18 37176 10777 2 820.392606 411.204 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2613.7 - 2.60E+06 - - - -1.1263 - 1.605 0.263 - 201.6 1 2 0 -0.0009 7 0 0 0 1.25E+09 5.75E+08 - - - 2.4823 1 230117_WJC_METTL3_WT_vs_EV_F05.10781.10781.2 1.98E-07 20-Nov K.FGDPVVQSDMK.H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1221.57 0.6 37177 10781 2 1221.570251 611.7923 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.21 2614.2 - 302309 - - - 0.2268 - 1.86 0.56 - 353.5 1 2 0 0.0003 11 0 0 0 1.18E+07 1.97E+07 - - - 4.8559 1 230117_WJC_METTL3_WT_vs_EV_F05.10793.10793.2 8.86E-07 13/22 R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 37180 10793 2 1474.780529 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2616 - 462423 - - - 1.7196 - 2.365 0.551 - 426.7 1 2 0 0.0025 12 0 0 0 3.43E+07 0.00E+00 - - - 5.3747 0.9642 230117_WJC_METTL3_WT_vs_EV_F05.10801.10801.2 0.00799 16-Nov R.PGPLLVSAR[166.11].R sp|Q9NUL7|DDX28_HUMAN 1 918.5526 8.83 37182 10801 2 918.554735 460.2836 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 10.18 2617.2 - 902147 - - - 2.3014 - 1.94 0.369 - 345.5 1 1 0 0.0021 9 0 0 0 5.89E+08 6.67E+07 - - - 3.683 1 230117_WJC_METTL3_WT_vs_EV_F05.10805.10805.2 0.000584 16-Oct K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 0.79 37183 10805 2 983.575865 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2617.7 - 700695 - - - -0.5236 - 2.119 0.462 - 488.2 1 2 0 -0.0005 9 0 0 0 7.20E+07 9.14E+07 - - - 4.6257 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.10815.10815.2 0.0123 20-Aug K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 3811.78 37185 10815 2 1106.550007 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2619.2 - 332052 - - - 3.2579 - 1.804 0.431 - 130.7 1 2 0 0.0036 11 0 0 0 2.06E+09 5.41E+05 - - - 3.8193 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.10831.10831.2 0.0128 16-Jul K.EIAEAYLGK.T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 992.5179 10.27 37188 10831 2 992.518636 497.2662 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 2621.8 - 1.65E+06 - - - 0.7798 - 1.338 0.212 - 201.9 1 2 0 0.0008 9 0 0 0 6.15E+07 5.99E+06 - - - 1.449 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.10835.10835.2 0.00178 14-Jul R.NGYGFINR.N "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 4 939.4563 0.36 37190 10835 2 939.457439 470.7354 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 8.75 2622.3 - 257070 - - - 1.2497 - 1.474 0.372 - 112.2 1 2 0 0.0012 8 0 0 0 9.01E+06 2.53E+07 - - - 2.9584 0.9919 230117_WJC_METTL3_WT_vs_EV_F05.10839.10839.2 0.908 12-Jun R.LILPEAK.V "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN,tr|A8MSZ8|A8MSZ8_HUMAN" 3 782.4902 1.46 37192 10839 2 782.491943 392.2524 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 6 2622.7 - 429837 - - - 2.239 - 1.115 0.186 - 116.9 1 2 0 0.0018 7 0 0 0 1.05E+08 7.20E+07 - - - 0.7592 0.8886 230117_WJC_METTL3_WT_vs_EV_F05.10853.10853.2 2.39 14-Jul K.EVDIYTVK[136.11].V "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 3 973.5212 0.55 37195 10853 2 973.519396 487.7679 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 2624.9 - 174031 - - - -1.8151 - 1.14 0.051 - 142.6 1 2 0 -0.0018 8 0 0 0 5.87E+06 1.06E+07 - - - -0.1877 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.10863.10863.2 0.0419 14-Aug R.VITALVER.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 899.544 0.36 37198 10863 2 899.545044 450.7793 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2626.4 - 1.28E+06 - - - 1.1417 - 1.673 0.281 - 195.7 1 2 0 0.001 8 0 0 0 2.99E+09 8.41E+09 - - - 2.6682 0.9933 230117_WJC_METTL3_WT_vs_EV_F05.10875.10875.2 0.665 12-Jul R.LILPEAK[136.11].V "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN,tr|A8MSZ8|A8MSZ8_HUMAN" 3 790.5044 1.47 37203 10875 2 790.505409 396.2595 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 6 2628 - 1.33E+06 - - - 1.2878 - 1.371 0.115 - 117.9 2 2 0 0.001 7 0 0 0 1.05E+08 7.19E+07 - - - 0.7554 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.10879.10879.2 0.429 12-Jul R.LPPDVLR.W sp|P78527|PRKDC_HUMAN 1 808.4807 2.27 37206 10879 2 808.482514 405.2476 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2628.5 - 404060 - - - 2.2573 - 1.444 0.172 - 185.4 1 2 0 0.0018 7 0 0 0 7.37E+07 3.25E+07 - - - 1.475 0.997 230117_WJC_METTL3_WT_vs_EV_F05.10898.10898.2 1.22 12-Aug R.LNELLVK.A "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L253|I3L253_HUMAN" 3 827.5117 2.13 37213 10898 2 827.512397 414.7631 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2631 - 900333 - - - 0.8979 - 1.693 0.093 - 198.9 1 2 0 0.0007 7 0 0 0 5.37E+08 2.52E+08 - - - 1.3959 0.998 230117_WJC_METTL3_WT_vs_EV_F05.10900.10900.2 0.904 12-Sep R.LNELLVK[136.11].A "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L253|I3L253_HUMAN" 3 835.5259 2.08 37214 10900 2 835.52679 418.7702 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2631.2 - 540130 - - - 1.1203 - 1.629 0.152 - 185.4 1 2 0 0.0009 7 0 0 0 5.37E+08 2.58E+08 - - - 1.7095 0.9832 230117_WJC_METTL3_WT_vs_EV_F05.10905.10905.2 2.42 14-Jun R.LLVVTDPR[166.11].A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 921.5523 2.75 37215 10905 2 921.55217 461.7834 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.84 2631.9 - 738618 - - - -0.127 - 1.257 0.094 - 93.8 1 2 0 -0.0001 8 0 0 0 1.51E+09 5.50E+08 - - - 0.4251 0.9934 230117_WJC_METTL3_WT_vs_EV_F05.10910.10910.2 0.213 12-May K.AC[160.03]TILLR.G "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 845.4793 14.02 37216 10910 2 845.480656 423.7469 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 8.29 2632.7 - 6.00E+06 - - - 1.5932 - 1.208 0.155 - 164.5 1 2 0 0.0013 7 0 0 0 4.35E+08 3.10E+07 - - - 0.7842 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.10953.10953.2 0.013 14-Jul R.VFVNPSLR.V sp|Q9HBH1|DEFM_HUMAN 1 930.5287 1.06 37230 10953 2 930.529403 466.2716 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 9.72 2638.9 - 2.09E+06 - - - 0.7544 - 1.726 0.295 - 198 1 2 0 0.0007 8 0 0 0 3.70E+08 3.47E+08 - - - 2.8658 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.10957.10957.2 0.428 14-Jul R.AIVPLEAR.M "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 867.5178 2.13 37233 10957 2 867.518827 434.7662 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 6.05 2639.4 - 226349 - - - 1.1815 - 1.343 0.185 - 182.3 1 2 0 0.001 8 0 0 0 1.05E+08 4.95E+07 - - - 1.2965 0.971 230117_WJC_METTL3_WT_vs_EV_F05.10970.10970.2 3.48 14-Jun K.ILPVGGIK[136.11].E "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN,tr|K7ERR6|K7ERR6_HUMAN" 4 803.536 1.36 37237 10970 2 803.537093 402.7753 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 8.75 2641.1 - 643789 - - - 1.3291 - 0.973 0.108 - 81 1 2 0 0.0011 8 0 0 0 4.76E+07 3.49E+07 - - - -0.2442 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.10972.10972.2 0.222 14-Sep R.VITALVER[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 909.5523 0.36 37238 10972 2 909.5539 455.7834 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2641.4 - 2.39E+07 - - - 1.7734 - 1.76 0.266 - 275.2 1 2 0 0.0016 8 0 0 0 2.99E+09 8.40E+09 - - - 2.7101 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.10978.10978.2 4.11E-06 22-Oct K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 2.3 37242 10978 2 1222.668228 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2642.1 - 188215 - - - 2.7489 - 2.026 0.416 - 302.9 1 2 0 0.0034 12 0 0 0 9.68E+07 4.21E+07 - - - 3.9703 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.10982.10982.2 5.61E-06 22-Dec K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 2.3 37245 10982 2 1214.653381 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2642.6 - 446106 - - - 2.2344 - 2.297 0.452 - 467.4 1 2 0 0.0027 12 0 0 0 9.69E+07 4.21E+07 - - - 4.5667 0.9335 230117_WJC_METTL3_WT_vs_EV_F05.10988.10988.2 0.0422 14-Jul Q.VLVLAPTR[166.11].E "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 877.5625 0.91 37247 10988 2 877.564063 439.7885 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.72 2643.5 - 556467 - - - 1.8289 - 1.622 0.28 - 198.3 1 1 0 0.0016 8 0 0 0 1.27E+08 1.40E+08 - - - 2.5673 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.10992.10992.2 0.162 14-Aug R.ILMAINGK.V sp|O00264|PGRC1_HUMAN 1 858.4997 0.86 37248 10992 2 858.502693 430.2571 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 8.75 2644.1 - 727056 - - - 3.4758 - 1.369 0.318 - 147.9 1 2 0 0.003 8 0 0 0 9.40E+07 1.10E+08 - - - 2.3361 0.8906 230117_WJC_METTL3_WT_vs_EV_F05.10993.10993.2 1.24 12-Jun R.LIPTELR[166.11].R "sp|Q96G21|IMP4_HUMAN,tr|F8WCN0|F8WCN0_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN" 4 850.5152 1.14 37249 10993 2 850.519476 426.2649 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2644.2 - 216163 - - - 5.0593 - 1.181 0.127 - 121.9 7 2 0 0.0043 7 0 0 0 1.69E+08 1.48E+08 - - - 0.1273 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.11015.11015.2 0.553 14-Jul R.ILMAINGK[136.11].V sp|O00264|PGRC1_HUMAN 1 866.5139 0.89 37254 11015 2 866.515704 434.2642 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 8.75 2647.7 - 1.72E+06 - - - 2.0715 - 1.266 0.274 - 123 1 2 0 0.0018 8 0 0 0 1.00E+08 1.13E+08 - - - 1.7756 0.902 230117_WJC_METTL3_WT_vs_EV_F05.11020.11020.2 0.017 14-Jun Q.VLVLAPTR.E "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 867.5542 0.91 37256 11020 2 867.55574 434.7844 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.72 2648.3 - 1.96E+06 - - - 1.7889 - 1.38 0.285 - 117.4 1 1 0 0.0016 8 0 0 0 1.27E+08 1.40E+08 - - - 2.1169 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.11029.11029.2 0.0308 12-Jun R.LIPTELR.R "sp|Q96G21|IMP4_HUMAN,tr|F8WCN0|F8WCN0_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN" 4 840.5069 1.06 37258 11029 2 840.50874 421.2607 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2649.6 - 1.93E+06 - - - 2.1856 - 1.229 0.209 - 153.3 1 2 0 0.0018 7 0 0 0 1.70E+08 1.60E+08 - - - 1.2375 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.11037.11037.2 0.322 14-Jul K.GIYALAAR.D "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 833.4759 0.98 37260 11037 2 833.47739 417.7452 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 8.75 2650.9 - 538546 - - - 1.7421 - 1.467 0.173 - 161.8 1 2 0 0.0015 8 0 0 0 5.67E+07 5.76E+07 - - - 1.4741 0.9907 230117_WJC_METTL3_WT_vs_EV_F05.11039.11039.2 0.436 18-May K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 1.6 37261 11039 2 1008.598523 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2651.1 - 168853 - - - 1.7272 - 1.113 0.211 - 60.7 6 2 0 0.0017 10 0 0 0 1.66E+07 1.04E+07 - - - 0.5501 0.9963 230117_WJC_METTL3_WT_vs_EV_F05.11057.11057.2 0.254 12-May R.NMAPDLR.Q "sp|P35611|ADDA_HUMAN,tr|E7EV99|E7EV99_HUMAN,tr|E7ENY0|E7ENY0_HUMAN,tr|A0A804HL01|A0A804HL01_HUMAN,tr|A0A0A0MSR2|A0A0A0MSR2_HUMAN,tr|D6RAH3|D6RAH3_HUMAN,tr|D6RF25|D6RF25_HUMAN,tr|D6RJE2|D6RJE2_HUMAN" 8 815.396 0.85 37265 11057 2 815.397344 408.7053 Alpha-adducin OS=Homo sapiens OX=9606 GN=ADD1 PE=1 SV=2 5.84 2653.8 - 740115 - - - 1.6814 - 1.29 0.188 - 114.5 1 2 0 0.0014 7 0 0 0 4.58E+07 5.38E+07 - - - 1.236 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.11060.11060.2 0.0122 12-Jul K.SVLIMGR[166.11].G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 784.4505 1.78 37266 11060 2 784.451703 393.2325 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.47 2654.2 - 313453 - - - 1.5782 - 1.608 0.227 - 179.4 1 2 0 0.0012 7 0 0 0 9.14E+07 5.13E+07 - - - 2.2223 0.9944 230117_WJC_METTL3_WT_vs_EV_F05.11068.11068.2 0.115 12-May K.DDAMLLK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 804.4051 1.35 37269 11068 2 804.406997 403.2098 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.21 2655.2 - 1.19E+06 - - - 2.3085 - 1.309 0.177 - 128.3 2 2 0 0.0019 7 0 0 0 4.45E+07 3.30E+07 - - - 1.0664 0.9903 230117_WJC_METTL3_WT_vs_EV_F05.11070.11070.2 1.74 12-Jul K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 0.96 37270 11070 2 828.475245 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2655.6 - 1.08E+06 - - - 2.338 - 1.404 0.074 - 173.4 1 2 0 0.0019 7 0 0 0 3.31E+10 3.43E+10 - - - 0.6621 0.9053 230117_WJC_METTL3_WT_vs_EV_F05.11080.11080.2 3.37 12-May K.FIEIAAR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 818.465 0.96 37273 11080 2 818.463326 410.2398 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2657.1 - 4.75E+06 - - - -2.0917 - 1.088 0.136 - 71.6 4 2 0 -0.0017 7 0 0 0 3.31E+10 3.43E+10 - - - 0.0433 0.9912 230117_WJC_METTL3_WT_vs_EV_F05.11096.11096.2 0.00778 20-Aug K.IGGIGTVPVGR.V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1024.6029 4.07 37282 11096 2 1024.599257 513.3087 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2659 - 432367 - - - -3.5838 - 1.761 0.333 - 127.7 2 2 0 -0.0037 11 0 0 0 7.90E+07 1.94E+07 - - - 2.8958 0.9949 230117_WJC_METTL3_WT_vs_EV_F05.11098.11098.2 0.635 12-Jul K.SVLIMGR.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 774.4422 1.49 37283 11098 2 774.442982 388.2284 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.47 2659.2 - 1.60E+06 - - - 1.0162 - 1.363 0.129 - 238.5 1 2 0 0.0008 7 0 0 0 9.41E+07 6.31E+07 - - - 0.9748 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.11101.11101.2 0.372 14-Jul K.AVVAALMK[136.11].A sp|P08240|SRPRA_HUMAN 1 809.4924 1.05 37284 11101 2 809.493137 405.7535 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 8.8 2659.6 - 653782 - - - 0.8536 - 1.413 0.283 - 160.6 1 2 0 0.0007 8 0 0 0 8.03E+07 7.65E+07 - - - 2.1737 0.995 230117_WJC_METTL3_WT_vs_EV_F05.11117.11117.2 1.06 14-Jul K.IGVTVLSR[166.11].L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 853.5261 0.91 37289 11117 2 853.524922 427.7703 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2661.9 - 748367 - - - -1.3474 - 1.722 0.177 - 117.8 1 2 0 -0.0011 8 0 0 0 4.57E+08 5.04E+08 - - - 1.9871 0.9949 230117_WJC_METTL3_WT_vs_EV_F05.11136.11136.2 0.842 14-Jul R.ILMGSTLR[166.11].K "sp|P10644|KAP0_HUMAN,sp|P31321|KAP1_HUMAN,tr|K7EM13|K7EM13_HUMAN,tr|C9JSK5|C9JSK5_HUMAN,tr|K7EKR1|K7EKR1_HUMAN,tr|K7EPB2|K7EPB2_HUMAN,tr|H7BYW5|H7BYW5_HUMAN" 7 899.5138 1.7 37294 11136 2 899.51417 450.7642 cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1A PE=1 SV=1 9.75 2664.6 - 599238 - - - 0.4191 - 1.26 0.185 - 126.3 1 2 0 0.0004 8 0 0 0 3.93E+07 2.31E+07 - - - 1.1043 0.9963 230117_WJC_METTL3_WT_vs_EV_F05.11139.11139.2 0.00444 14-Sep K.IGVTVLSR.L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 843.5178 0.91 37295 11139 2 843.515922 422.7662 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2664.9 - 2.53E+06 - - - -2.2288 - 1.823 0.28 - 264.4 1 2 0 -0.0019 8 0 0 0 4.57E+08 5.04E+08 - - - 2.9195 0.9552 230117_WJC_METTL3_WT_vs_EV_F05.11146.11146.2 0.267 12-Jul R.VYLGALK[136.11].Y sp|Q6P2Q9|PRP8_HUMAN 1 770.4782 1.06 37296 11146 2 770.476552 386.2464 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.56 2666 - 3.10E+06 - - - -2.1078 - 1.377 0.073 - 177.8 1 2 0 -0.0016 7 0 0 0 2.42E+08 2.28E+08 - - - 0.5933 0.984 230117_WJC_METTL3_WT_vs_EV_F05.11159.11159.2 1.75 12-Aug K.LGITQLR.F "sp|Q9Y285|SYFA_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 3 799.4916 2.36 37299 11159 2 799.49076 400.7531 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 9.75 2667.9 - 1.48E+06 - - - -1.0357 - 1.775 0 - 176.6 1 2 0 -0.0008 7 0 0 0 1.63E+08 6.90E+07 - - - 0.8589 0.9007 230117_WJC_METTL3_WT_vs_EV_F05.11165.11165.2 0.00552 14-Jul K.LTGVFAPR[166.11].P "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 869.4999 0.97 37301 11165 2 869.49942 435.7572 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2668.7 - 2.14E+06 - - - -0.5037 - 1.732 0.283 - 135.6 1 1 0 -0.0004 8 0 0 0 2.26E+09 2.32E+09 - - - 2.7877 0.9592 230117_WJC_METTL3_WT_vs_EV_F05.11171.11171.2 1.48 12-Jun K.LPYSTFR[166.11].T "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 892.4682 1.22 37303 11171 2 892.467655 447.2414 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.75 2669.4 - 1.27E+06 - - - -0.6364 - 1.1 0.092 - 132.7 1 2 0 -0.0006 7 0 0 0 2.03E+08 1.66E+08 - - - 0.0223 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.11189.11189.2 0.447 12-Jun R.VTVPLVR[166.11].R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 792.5097 0.96 37305 11189 2 792.509463 397.2621 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2672.5 - 2.38E+06 - - - -0.2915 - 1.392 0.198 - 150.8 1 2 0 -0.0002 7 0 0 0 4.01E+08 4.20E+08 - - - 1.5513 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.11192.11192.2 0.117 12-Jul R.VTVPLVR.R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 782.5014 0.95 37306 11192 2 782.501321 392.258 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2672.9 - 1.90E+06 - - - -0.1316 - 1.428 0.201 - 203.3 1 2 0 -0.0001 7 0 0 0 4.01E+08 4.20E+08 - - - 1.6544 0.9465 230117_WJC_METTL3_WT_vs_EV_F05.11203.11203.2 0.0839 14-Sep K.LTGVFAPR.P "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 859.4916 0.98 37310 11203 2 859.491991 430.7531 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2674.3 - 1.79E+07 - - - 0.4689 - 1.904 0.27 - 362.6 1 1 0 0.0004 8 0 0 0 2.27E+09 2.33E+09 - - - 2.9772 0.9946 230117_WJC_METTL3_WT_vs_EV_F05.11249.11249.2 0.21 18-May K.NGQDLGVAFK[136.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1055.5491 1.57 37323 11249 2 1055.548445 528.7818 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2681.3 - 244738 - - - -0.6291 - 1.277 0.262 - 73.4 2 2 0 -0.0007 10 0 0 0 5.40E+07 3.44E+07 - - - 1.524 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.11270.11270.2 0.0478 12-Jun K.FMTDPIR.L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 878.432 0.91 37330 11270 2 878.43339 440.2233 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2684.1 - 1.19E+06 - - - 1.555 - 1.211 0.266 - 169.1 1 2 0 0.0014 7 0 0 0 1.06E+08 1.17E+08 - - - 1.6119 0.988 230117_WJC_METTL3_WT_vs_EV_F05.11274.11274.2 0.449 12-Jul R.LIVNIAK[136.11].V sp|Q15058|KIF14_HUMAN 1 777.5204 1.54 37331 11274 2 777.522529 389.7675 Kinesin-like protein KIF14 OS=Homo sapiens OX=9606 GN=KIF14 PE=1 SV=1 8.75 2684.6 - 226487 - - - 2.7703 - 1.207 0.14 - 98.7 1 2 0 0.0022 7 0 0 0 1.30E+07 8.44E+06 - - - 0.6705 0.9844 230117_WJC_METTL3_WT_vs_EV_F05.11282.11282.2 1.37 12-Jun K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 1.3 37334 11282 2 828.475361 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2685.7 - 2.84E+06 - - - 2.4781 - 1.458 0.019 - 149 1 2 0 0.0021 7 0 0 0 1.97E+08 1.52E+08 - - - 0.3754 0.9869 230117_WJC_METTL3_WT_vs_EV_F05.11287.11287.2 0.0749 12-Jul K.FMTDPIR[166.11].L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 888.4403 0.99 37336 11287 2 888.442899 445.2274 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2686.4 - 2.66E+06 - - - 2.9321 - 1.007 0.219 - 189.8 1 2 0 0.0026 7 0 0 0 1.16E+08 1.17E+08 - - - 0.6798 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.11297.11297.2 0.000424 14-Aug K.FGPALSVK[136.11].V "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 825.484 4.87 37341 11297 2 825.486584 413.7493 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.75 2687.7 - 2.18E+06 - - - 3.1424 - 1.839 0.445 - 192.4 1 2 0 0.0026 8 0 0 0 2.99E+09 6.15E+08 - - - 4.1643 0.9256 230117_WJC_METTL3_WT_vs_EV_F05.11304.11304.2 1.34 20-May K.ETTIDGEELVK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1240.6278 0.8 37345 11304 2 1240.633948 621.3212 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4 2688.6 - 61117.3 - - - 4.9451 - 1.134 0.151 - 72.6 2 2 0 0.0061 11 0 0 0 2.16E+06 2.70E+06 - - - 0.3601 0.998 230117_WJC_METTL3_WT_vs_EV_F05.11307.11307.2 0.0609 12-Aug R.IVYLYTK[136.11].K sp|P49207|RL34_HUMAN 1 906.5306 0.74 37346 11307 2 906.534045 454.2726 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 8.5 2689 - 1.66E+06 - - - 3.7947 - 1.6 0.314 - 210.4 1 2 0 0.0034 7 0 0 0 7.33E+08 9.86E+08 - - - 2.8484 0.9829 230117_WJC_METTL3_WT_vs_EV_F05.11319.11319.2 0.437 14-Aug K.MLDAAVIK[136.11].M sp|Q9BXP5|SRRT_HUMAN 1 867.4979 1.03 37354 11319 2 867.500895 434.7562 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 5.59 2690.6 - 3.23E+06 - - - 3.4236 - 1.333 0.108 - 149.6 1 2 0 0.003 8 0 0 0 2.28E+09 2.22E+09 - - - 0.7046 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.11324.11324.2 0.000833 18-Sep K.NGQDLGVAFK.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1047.5349 1.62 37357 11324 2 1047.538222 524.7747 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2691.3 - 522568 - - - 3.1627 - 1.852 0.442 - 328.3 1 2 0 0.0033 10 0 0 0 5.59E+07 3.44E+07 - - - 4.0248 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.11325.11325.2 0.202 14-Aug K.LLLGDAPR.L "sp|Q96C00|ZBTB9_HUMAN,tr|A0A087X1K1|A0A087X1K1_HUMAN" 2 853.5022 0.68 37358 11325 2 853.504971 427.7584 Zinc finger and BTB domain-containing protein 9 OS=Homo sapiens OX=9606 GN=ZBTB9 PE=1 SV=1 5.84 2691.4 - 366730 - - - 3.3029 - 1.531 0.229 - 159.7 1 2 0 0.0028 8 0 0 0 2.62E+07 3.83E+07 - - - 2.0161 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.11330.11330.2 1.99 14-Aug R.VLAVTAIR.E sp|P22102|PUR2_HUMAN 1 841.5385 2.49 37361 11330 2 841.540322 421.7765 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2692.1 - 921274 - - - 2.1199 - 1.796 0.249 - 246.9 1 2 0 0.0018 8 0 0 0 3.48E+08 1.40E+08 - - - 2.6456 0.9945 230117_WJC_METTL3_WT_vs_EV_F05.11331.11331.2 0.0658 14-Jul K.ALSVGLVK.G "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 3 785.5011 1.68 37362 11331 2 785.503331 393.7578 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 8.8 2692.2 - 366603 - - - 2.853 - 1.365 0.18 - 128.1 1 2 0 0.0022 8 0 0 0 1.10E+08 6.53E+07 - - - 1.3082 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.11332.11332.2 0.00433 12-Jul K.MMEIMTR[166.11].E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 920.4157 0.86 37363 11332 2 920.417701 461.2151 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2692.3 - 485878 - - - 2.136 - 1.394 0.214 - 228.4 1 2 0 0.002 7 0 0 0 1.25E+08 1.46E+08 - - - 1.6735 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.11343.11343.2 0.0316 12-Aug K.MMEIMTR.E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 910.4075 0.86 37369 11343 2 910.410152 456.211 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2693.8 - 2.16E+06 - - - 2.9514 - 1.387 0.369 - 181.8 1 2 0 0.0027 7 0 0 0 1.25E+08 1.46E+08 - - - 2.8022 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.11345.11345.2 0.00642 16-Sep R.MVGGVLVER[166.11].T sp|Q9UHV9|PFD2_HUMAN 1 968.5353 1.49 37370 11345 2 968.537717 485.2749 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 5.75 2694 - 1.37E+06 - - - 2.5399 - 1.662 0.342 - 218.1 1 2 0 0.0025 9 0 0 0 5.93E+07 3.97E+07 - - - 3.036 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.11348.11348.2 0.00496 18-Jun K.C[160.03]PFTGNVSIR[166.11].G "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1159.5683 0.87 37371 11348 2 1159.570442 580.7915 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.25 2694.4 - 96321.5 - - - 1.8058 - 1.181 0.386 - 130.7 1 2 0 0.0021 10 0 0 0 3.47E+06 3.97E+06 - - - 2.3557 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.11351.11351.2 0.00131 12-Jul K.MMVAGFK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 790.3961 0.89 37372 11351 2 790.397616 396.2053 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2694.8 - 1.36E+06 - - - 1.9155 - 1.554 0.414 - 245.4 1 2 0 0.0015 7 0 0 0 5.63E+09 6.36E+09 - - - 3.4951 0.9858 230117_WJC_METTL3_WT_vs_EV_F05.11355.11355.2 4.02 12-Jun K.YLDEIVK.E sp|P12270|TPR_HUMAN 1 878.4749 1.83 37373 11355 2 878.476907 440.2447 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.37 2695.5 - 641195 - - - 2.2448 - 1.043 0.161 - 105.9 1 2 0 0.002 7 0 0 0 3.59E+07 1.96E+07 - - - 0.3629 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.11363.11363.2 0.00159 12-Jul K.MMVAGFK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 782.3819 0.89 37378 11363 2 782.382956 392.1982 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2696.5 - 3.64E+06 - - - 1.3472 - 1.494 0.471 - 200.1 1 2 0 0.0011 7 0 0 0 5.64E+09 6.36E+09 - - - 3.7915 0.9945 230117_WJC_METTL3_WT_vs_EV_F05.11365.11365.2 1.01 18-Nov K.YEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1178.5932 684.21 37380 11365 2 1178.589183 590.3039 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2696.7 - 186114 - - - -3.3676 - 2.093 0.305 - 521.8 1 2 0 -0.004 10 0 0 0 2.07E+07 3.02E+04 - - - 3.3541 0.9651 230117_WJC_METTL3_WT_vs_EV_F05.11371.11371.2 3.54 14-Jun K.IVGYVLAK.M "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN" 4 861.5324 1.27 37382 11371 2 861.533054 431.7735 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 8.59 2697.5 - 1.31E+06 - - - 0.7707 - 0.99 0.091 - 74.5 1 2 0 0.0007 8 0 0 0 1.56E+08 1.23E+08 - - - -0.3174 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.11372.11372.3 0.000223 Oct-52 K.SQIHDIVLVGGSTR.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1480.7998 27.59 37383 11372 3 1480.800174 494.6072 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2697.6 - 192815 - - - 0.2586 - 2.02 0.437 - 130 1 2 0 0.0004 14 0 0 0 1.31E+07 4.75E+05 - - - 5.2805 0.9534 230117_WJC_METTL3_WT_vs_EV_F05.11373.11373.2 2.66 14-Jul K.IVGYVLAK[136.11].M "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN" 4 869.5466 1.27 37384 11373 2 869.547503 435.7806 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 8.59 2697.7 - 1.13E+06 - - - 1.05 - 1.141 0.003 - 109.4 1 2 0 0.0009 8 0 0 0 1.56E+08 1.23E+08 - - - -0.5393 0.9957 230117_WJC_METTL3_WT_vs_EV_F05.11395.11395.2 0.239 14-Jun R.GLGGIMVK.R sp|O94776|MTA2_HUMAN 1 773.4469 1.3 37393 11395 2 773.447644 387.7307 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 2700.6 - 914048 - - - 0.9025 - 1.148 0.226 - 96.7 1 2 0 0.0007 8 0 0 0 4.65E+07 3.57E+07 - - - 1.1263 0.994 230117_WJC_METTL3_WT_vs_EV_F05.11400.11400.3 0.17 Jun-40 K.IWHHTFYNELR.V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1514.7419 1.31 37395 11400 3 1514.738608 505.9212 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2701.3 - 193460 - - - -2.1614 - 1.413 0.318 - 41.7 1 2 0 -0.0033 11 0 0 0 8.71E+06 6.65E+06 - - - 3.0666 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.11437.11437.2 0.103 14-Jun R.VILPDDVR.D "sp|Q3YEC7|RABL6_HUMAN,tr|F2Z2T0|F2Z2T0_HUMAN,tr|H0Y7H6|H0Y7H6_HUMAN,tr|G3V154|G3V154_HUMAN" 4 925.5233 102.95 37406 11437 2 925.524188 463.7689 Rab-like protein 6 OS=Homo sapiens OX=9606 GN=RABL6 PE=1 SV=2 4.21 2706.6 - 1.23E+06 - - - 0.9789 - 1.343 0.397 - 79 1 2 0 0.0009 8 0 0 0 4.41E+07 4.28E+05 - - - 2.8624 0.9902 230117_WJC_METTL3_WT_vs_EV_F05.11459.11459.2 1.14 12-Aug K.LAPFIAK[136.11].R "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN,tr|K7ELX4|K7ELX4_HUMAN" 3 766.4833 1.66 37410 11459 2 766.483637 384.2489 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 8.75 2709.9 - 1.53E+06 - - - 0.4906 - 1.497 0.038 - 169.3 1 2 0 0.0004 7 0 0 0 3.53E+08 2.12E+08 - - - 0.5999 0.9845 230117_WJC_METTL3_WT_vs_EV_F05.11486.11486.2 0.0575 14-May R.LLVPGTYK[136.11].L "sp|O75976|CBPD_HUMAN,tr|J3QQJ4|J3QQJ4_HUMAN" 2 897.5415 0.78 37421 11486 2 897.5399 449.778 Carboxypeptidase D OS=Homo sapiens OX=9606 GN=CPD PE=1 SV=2 8.59 2713.5 - 202745 - - - -1.7871 - 1.089 0.265 - 56.2 1 2 0 -0.0016 8 0 0 0 1.16E+07 1.50E+07 - - - 1.2549 0.9868 230117_WJC_METTL3_WT_vs_EV_F05.11496.11496.2 1.22 14-Jul R.TIAPIIGR.T sp|Q99459|CDC5L_HUMAN 1 839.5229 3.64 37425 11496 2 839.523031 420.7687 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.41 2714.8 - 355191 - - - 0.1703 - 1.261 0.101 - 116 1 2 0 0.0001 8 0 0 0 7.67E+07 2.10E+07 - - - 0.4864 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.11500.11500.2 0.715 14-Jul R.TIAPIIGR[166.11].T sp|Q99459|CDC5L_HUMAN 1 849.5312 2.73 37427 11500 2 849.532892 425.7729 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.41 2715.4 - 613059 - - - 2.0411 - 1.284 0.209 - 166.1 1 2 0 0.0017 8 0 0 0 5.82E+07 2.13E+07 - - - 1.3381 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.11504.11504.2 0.0115 16-Oct R.LLSPLSSAR[166.11].L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 952.5581 1.09 37429 11504 2 952.559627 477.2863 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 2715.9 - 1.69E+06 - - - 1.602 - 1.813 0.313 - 345 1 2 0 0.0015 9 0 0 0 1.91E+08 1.76E+08 - - - 3.0737 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.11506.11506.2 0.0248 14-Jul K.GLYPAPLK[136.11].L "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 865.5153 1.72 37431 11506 2 865.516692 433.7649 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.59 2716.2 - 455842 - - - 1.6198 - 1.271 0.274 - 159.6 1 2 0 0.0014 8 0 0 0 5.60E+07 3.26E+07 - - - 1.7876 0.9891 230117_WJC_METTL3_WT_vs_EV_F05.11512.11512.2 0.602 12-Aug R.YLLYGEK[136.11].G "sp|P51398|RT29_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GYL9|V9GYL9_HUMAN" 3 892.4786 0.37 37434 11512 2 892.481104 447.2466 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 6 2716.9 - 729119 - - - 2.8393 - 1.262 0.135 - 238 1 2 0 0.0025 7 0 0 0 5.17E+07 1.41E+08 - - - 0.7746 0.9697 230117_WJC_METTL3_WT_vs_EV_F05.11521.11521.2 1.27 14-Jun R.IGLETSLR[166.11].Y sp|Q9Y230|RUVB2_HUMAN 1 897.5159 1.63 37438 11521 2 897.513832 449.7652 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6 2718 - 170136 - - - -2.3064 - 1.149 0.206 - 67.2 1 2 0 -0.0021 8 0 0 0 3.87E+07 2.37E+07 - - - 0.9808 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.11538.11538.2 0.0318 16-Sep R.LLSPLSSAR.L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 942.5498 1.09 37446 11538 2 942.551725 472.2822 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 2720.1 - 3.95E+06 - - - 2.0094 - 1.803 0.275 - 305.7 1 2 0 0.0019 9 0 0 0 1.91E+08 1.76E+08 - - - 2.7769 0.9722 230117_WJC_METTL3_WT_vs_EV_F05.11544.11544.2 2.14 12-Jun K.IIDDLLK[136.11].N "sp|Q9H227|GBA3_HUMAN,tr|A0A087WTY7|A0A087WTY7_HUMAN" 2 836.5099 1.04 37447 11544 2 836.510832 419.2622 Cytosolic beta-glucosidase OS=Homo sapiens OX=9606 GN=GBA3 PE=1 SV=2 4.21 2721.1 - 1.18E+06 - - - 1.15 - 1.322 0.018 - 79.8 4 2 0 0.001 7 0 0 0 6.42E+08 6.18E+08 - - - -0.2108 0.9897 230117_WJC_METTL3_WT_vs_EV_F05.11546.11546.2 0.114 16-Aug R.LLPAELPAK[136.11].R sp|P78527|PRKDC_HUMAN 1 958.5943 1.24 37448 11546 2 958.600794 480.3044 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2721.3 - 343129 - - - 6.8079 - 1.59 0.407 - 171.6 1 2 0 0.0065 9 0 0 0 5.08E+07 4.09E+07 - - - 3.3867 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.11550.11550.2 0.473 12-Aug R.IDGVLIR.M sp|O75663|TIPRL_HUMAN 1 784.4807 2.73 37449 11550 2 784.482623 393.2476 TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2 5.84 2721.9 - 800543 - - - 2.4653 - 1.612 0.152 - 141.4 1 2 0 0.0019 7 0 0 0 7.48E+07 2.74E+07 - - - 1.676 0.9835 230117_WJC_METTL3_WT_vs_EV_F05.11554.11554.2 0.392 12-Aug R.VAGIFPR[166.11].L "sp|O96005|CLPT1_HUMAN,tr|K7EJ16|K7EJ16_HUMAN" 2 768.4522 0.81 37450 11554 2 768.453378 385.2334 Cleft lip and palate transmembrane protein 1 OS=Homo sapiens OX=9606 GN=CLPTM1 PE=1 SV=1 9.72 2722.4 - 1.04E+06 - - - 1.5603 - 1.321 0.029 - 242.2 1 2 0 0.0012 7 0 0 0 5.82E+07 7.18E+07 - - - 0.1369 0.8503 230117_WJC_METTL3_WT_vs_EV_F05.11556.11556.2 11 12-Jun R.FPGAYLK.G "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 794.4327 1.44 37451 11556 2 794.435342 398.2236 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.59 2722.7 - 1.03E+06 - - - 3.3559 - 0.963 0.034 - 74.6 1 2 0 0.0027 7 0 0 0 1.07E+08 7.43E+07 - - - -0.8282 0.986 230117_WJC_METTL3_WT_vs_EV_F05.11558.11558.2 1.19 12-May K.IIVDELK.Q "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|H0Y9P0|H0Y9P0_HUMAN,tr|D6RF23|D6RF23_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 9 828.4957 1.04 37452 11558 2 828.4979 415.2551 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 4.37 2722.9 - 4.03E+06 - - - 2.6916 - 1.292 0.121 - 65.2 3 2 0 0.0022 7 0 0 0 6.42E+08 6.18E+08 - - - 0.5326 0.86 230117_WJC_METTL3_WT_vs_EV_F05.11561.11561.2 0.0377 16-Jul N.LVIITAGAR[166.11].Q "sp|Q9BYZ2|LDH6B_HUMAN,sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 7 922.5839 0.95 37453 11561 2 922.585659 462.2992 L-lactate dehydrogenase A-like 6B OS=Homo sapiens OX=9606 GN=LDHAL6B PE=1 SV=3 9.75 2723.3 - 3.09E+06 - - - 1.8828 - 1.519 0.223 - 131.2 2 1 0 0.0017 9 0 0 0 1.58E+08 1.67E+08 - - - 1.7625 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.11565.11565.2 0.00648 14-Aug R.FGPLASVK.L "sp|O15042|SR140_HUMAN,tr|E7EW00|E7EW00_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H0Y8D9|H0Y8D9_HUMAN" 4 817.4698 0.16 37454 11565 2 817.471018 409.7422 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 8.75 2723.9 - 1.58E+06 - - - 1.5022 - 1.749 0.297 - 195.5 1 2 0 0.0012 8 0 0 0 1.24E+08 8.00E+08 - - - 2.9203 0.875 230117_WJC_METTL3_WT_vs_EV_F05.11585.11585.2 0.111 16-Jun K.VDEIVVLSG.D "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 3 929.507 - 37462 11585 2 929.508065 465.7608 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 3.67 2726.6 - 1.35E+06 - - - 1.1856 - 1.366 0.254 - 54.5 1 1 0 0.0011 9 0 0 0 - - - - - 1.819 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.11597.11597.2 0.0128 14-Aug K.MVSAAFMK.K "sp|P25205|MCM3_HUMAN,tr|Q7Z6P5|Q7Z6P5_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 4 883.4296 2.81 37465 11597 2 883.430756 442.7221 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 8.5 2728.4 - 1.29E+06 - - - 1.33 - 1.497 0.349 - 229.4 1 2 0 0.0012 8 0 0 0 5.72E+07 2.03E+07 - - - 2.8352 0.9864 230117_WJC_METTL3_WT_vs_EV_F05.11601.11601.2 1.82 20-Jun K.VLFSSNGGVVK[136.11].G "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 1113.6274 1.19 37467 11601 2 1113.62947 557.821 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.72 2728.9 - 244351 - - - 1.8956 - 1.033 0.16 - 77.7 1 2 0 0.0021 11 0 0 0 1.07E+07 9.06E+06 - - - 0.3099 0.986 230117_WJC_METTL3_WT_vs_EV_F05.11616.11616.2 0.418 14-Jul K.NIILGGVK.A "sp|P22314|UBA1_HUMAN,tr|Q5JRS3|Q5JRS3_HUMAN,tr|Q5JRS2|Q5JRS2_HUMAN,tr|Q5JRS0|Q5JRS0_HUMAN,tr|Q5JRS1|Q5JRS1_HUMAN,tr|Q5JRR9|Q5JRR9_HUMAN" 6 812.512 2.4 37470 11616 2 812.51369 407.2633 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 8.75 2731.1 - 295379 - - - 2.0935 - 1.363 0.067 - 125.2 2 2 0 0.0017 8 0 0 0 3.48E+07 1.45E+07 - - - 0.3349 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.11618.11618.2 0.000173 12-Jul K.C[160.03]PVFVVR.W "sp|Q9C0J8|WDR33_HUMAN,tr|C9J8B4|C9J8B4_HUMAN" 2 875.4687 1.61 37471 11618 2 875.470155 438.7416 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 8.25 2731.4 - 1.21E+06 - - - 1.6117 - 1.635 0.455 - 225.6 1 2 0 0.0014 7 0 0 0 9.86E+07 6.11E+07 - - - 3.959 1 230117_WJC_METTL3_WT_vs_EV_F05.11619.11619.3 3.89E-13 16/84 K.DHTPSQELALTQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2270.0411 999 37472 11619 3 2270.044596 757.6876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2731.5 - 162294 - - - 1.5414 - 3.595 0.696 - 241.2 1 2 0 0.0035 22 0 0 0 4.98E+06 0.00E+00 - - - 9.3323 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.11623.11623.2 0.138 14-Aug K.LINAVELK[136.11].K sp|P56192|SYMC_HUMAN 1 906.563 1.07 37474 11623 2 906.564624 454.2888 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6 2732 - 3.92E+06 - - - 1.8267 - 1.625 0.294 - 160.6 1 2 0 0.0017 8 0 0 0 1.99E+08 1.86E+08 - - - 2.6762 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.11632.11632.2 0.168 14-Aug R.LVSLIGSK.T "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 815.5117 2.07 37477 11632 2 815.513671 408.7631 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 2733.3 - 370314 - - - 2.4733 - 1.7 0.171 - 141.1 1 2 0 0.002 8 0 0 0 7.33E+07 3.54E+07 - - - 1.9037 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.11636.11636.2 0.00735 16-Aug K.NDLAVVDVR[166.11].L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1009.5432 0.77 37479 11636 2 1009.546239 505.7789 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.21 2733.8 - 341159 - - - 3.0311 - 1.576 0.323 - 270.8 1 2 0 0.0031 9 0 0 0 1.38E+07 1.79E+07 - - - 2.7417 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.11647.11647.2 0.0145 16-May K.SC[160.03]AHDWVYE.- "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 3 1165.4499 - 37486 11647 2 1165.453629 583.7322 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 4.71 2735.1 - 60217.3 - - - 3.2348 - 1.024 0.384 - 79.4 1 2 0 0.0038 9 0 0 0 - - - - - 1.9447 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.11655.11655.2 0.0561 14-Aug R.LLGQIVDR.C sp|Q96I24|FUBP3_HUMAN 1 912.5393 1.47 37488 11655 2 912.54144 457.2769 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2736.3 - 2.05E+07 - - - 2.3824 - 1.594 0.334 - 221.5 1 2 0 0.0022 8 0 0 0 1.09E+09 7.39E+08 - - - 2.9134 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.11657.11657.2 0.0486 20-Jul K.LLAETVAPAVR[166.11].G "sp|Q9BSJ8|ESYT1_HUMAN,tr|F8VZB1|F8VZB1_HUMAN" 2 1148.6793 0.66 37490 11657 2 1148.678237 575.3469 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6 2736.6 - 211388 - - - -0.9071 - 1.509 0.331 - 105.4 1 2 0 -0.001 11 0 0 0 1.16E+07 1.75E+07 - - - 2.5985 1 230117_WJC_METTL3_WT_vs_EV_F05.11664.11664.3 1.05E-07 13/68 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 2.56 37493 11664 3 2070.874924 691.296 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2737.6 - 68832.5 - - - 4.1683 - 2.625 0.739 - 118.7 1 2 0 0.0086 18 0 0 0 6.62E+06 2.59E+06 - - - 9.1799 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.11672.11672.2 0.0393 14-Oct R.LGMGLVSR.S "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 831.4637 1.63 37497 11672 2 831.465208 416.7391 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 9.75 2738.7 - 1.17E+06 - - - 1.8642 - 2.182 0.327 - 297.4 1 2 0 0.0015 8 0 0 0 6.22E+07 3.81E+07 - - - 3.8089 0.9833 230117_WJC_METTL3_WT_vs_EV_F05.11683.11683.2 1.73 14-Jun R.LVSLIGSK[136.11].T "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 823.5259 2.09 37501 11683 2 823.526973 412.7702 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 2740.3 - 925252 - - - 1.3588 - 1.173 0.099 - 65.5 2 2 0 0.0011 8 0 0 0 7.40E+07 3.54E+07 - - - 0.1186 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.11684.11684.2 0.00924 20-Oct K.LLAETVAPAVR.G "sp|Q9BSJ8|ESYT1_HUMAN,tr|F8VZB1|F8VZB1_HUMAN" 2 1138.671 0.7 37502 11684 2 1138.674824 570.3428 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6 2740.4 - 319457 - - - 3.3504 - 1.982 0.375 - 365.8 1 2 0 0.0038 11 0 0 0 1.15E+07 1.64E+07 - - - 3.6602 0.9765 230117_WJC_METTL3_WT_vs_EV_F05.11697.11697.3 1.54E-06 Sep-68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 2.55 37506 11697 3 2079.877964 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2742.3 - 74706.8 - - - 479.8121 - 2.056 0.569 - 41 1 2 0 0.9975 18 0 0 0 6.59E+06 2.59E+06 - - - 6.4023 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.11700.11700.2 0.0966 14-Aug K.LGDIMGVK[136.11].K sp|Q92620|PRP16_HUMAN 1 839.4666 0.19 37507 11700 2 839.467633 420.7406 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38 PE=1 SV=2 5.84 2742.7 - 363460 - - - 1.2008 - 1.504 0.317 - 102.5 1 2 0 0.001 8 0 0 0 9.15E+06 4.82E+07 - - - 2.6129 0.9927 230117_WJC_METTL3_WT_vs_EV_F05.11705.11705.2 3.92 12-Aug K.LGLQSLR[166.11].N "sp|P18085|ARF4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 3 795.4842 2.52 37510 11705 2 795.484206 398.7494 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 9.75 2743.4 - 1.24E+06 - - - -0.0025 - 1.456 0.101 - 179.7 1 2 0 0 7 0 0 0 2.12E+08 8.43E+07 - - - 0.9774 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.11706.11706.2 0.014 12-Jul R.VFVVMEK.L "sp|Q15139|KPCD1_HUMAN,sp|O94806|KPCD3_HUMAN,sp|Q9BZL6|KPCD2_HUMAN,tr|M0R2Z8|M0R2Z8_HUMAN,tr|F8WBA3|F8WBA3_HUMAN" 5 850.4623 0.21 37511 11706 2 850.46311 426.2384 Serine\threonine-protein kinase D1 OS=Homo sapiens OX=9606 GN=PRKD1 PE=1 SV=2 5.97 2743.5 - 144835 - - - 0.9983 - 1.604 0.279 - 126.7 1 2 0 0.0008 7 0 0 0 1.40E+07 6.61E+07 - - - 2.5986 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.11718.11718.2 0.0131 20-Oct R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 0.99 37515 11718 2 1174.720306 588.3655 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2745.2 - 369145 - - - 3.2323 - 1.955 0.354 - 299 1 2 0 0.0038 11 0 0 0 5.69E+07 5.74E+07 - - - 3.468 0.999 230117_WJC_METTL3_WT_vs_EV_F05.11719.11719.2 0.0318 20-Nov R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 0.99 37516 11719 2 1166.705606 584.3584 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2745.3 - 267449 - - - 2.8259 - 2.1 0.255 - 337.9 1 2 0 0.0033 11 0 0 0 5.69E+07 5.74E+07 - - - 2.9305 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.11726.11726.3 0.0137 16/40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 0.78 37521 11726 3 1174.71878 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2746.1 - 3.28E+06 - - - 1.9332 - 2.651 0.306 - 221.2 1 2 0 0.0023 11 0 0 0 2.53E+08 3.24E+08 - - - 4.7206 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.11729.11729.2 0.00336 16-May K.ESYSVYVYK[136.11].V "sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 10 1144.5532 1.57 37524 11729 2 1144.557356 573.2839 Histone H2B type 2-F OS=Homo sapiens OX=9606 GN=H2BC18 PE=1 SV=3 6.1 2746.5 - 165607 - - - 3.639 - 1.229 0.363 - 78.8 1 2 0 0.0042 9 0 0 0 7.32E+06 4.66E+06 - - - 2.3174 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.11733.11733.3 0.0013 13/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 0.78 37526 11733 3 1166.704592 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2747 - 3.96E+06 - - - 1.9568 - 2.493 0.273 - 167.2 1 2 0 0.0023 11 0 0 0 2.53E+08 3.24E+08 - - - 4.1781 0.9743 230117_WJC_METTL3_WT_vs_EV_F05.11734.11734.2 0.000274 16-Oct L.ASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 940.5342 1 37527 11734 2 940.536124 471.2744 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 2747.1 - 326989 - - - 2.0658 - 2.112 0.403 - 375.9 1 1 0 0.0019 9 0 0 0 2.00E+07 2.00E+07 - - - 4.1799 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.11735.11735.2 0.00344 14-Aug R.ILDAPEIR[166.11].N sp|Q12834|CDC20_HUMAN 1 935.5316 1.86 37528 11735 2 935.534308 468.7731 Cell division cycle protein 20 homolog OS=Homo sapiens OX=9606 GN=CDC20 PE=1 SV=2 4.37 2747.3 - 210965 - - - 2.9459 - 1.811 0.345 - 160 1 2 0 0.0028 8 0 0 0 1.60E+07 8.60E+06 - - - 3.3794 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.11739.11739.2 0.0578 24-Jul R.SILSPGGSC[160.03]GPIK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1279.6686 0.98 37530 11739 2 1279.671601 640.8416 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 7.94 2747.7 - 56488.2 - - - 2.3662 - 1.627 0.233 - 97.4 1 2 0 0.003 13 0 0 0 4.60E+06 4.68E+06 - - - 2.0102 0.9635 230117_WJC_METTL3_WT_vs_EV_F05.11744.11744.2 0.0188 18-Nov L.LASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1053.6182 0.73 37534 11744 2 1053.620766 527.8164 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2748.3 - 213606 - - - 2.3927 - 2.199 0.336 - 353.3 1 1 0 0.0025 10 0 0 0 9.39E+06 1.28E+07 - - - 3.7215 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.11754.11754.2 0.00902 12-Jun K.LDPVLYR[166.11].K "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 884.4995 0.92 37537 11754 2 884.500998 443.257 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 5.84 2749.7 - 2.24E+06 - - - 1.6676 - 1.249 0.196 - 168.7 1 2 0 0.0015 7 0 0 0 1.20E+08 1.30E+08 - - - 1.1927 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.11755.11755.2 5.06E-05 18-Sep K.YEELQVTVGR.H sp|P35908|K22E_HUMAN 1 1192.6088 19.17 37538 11755 2 1192.61095 597.3117 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.53 2749.8 - 64633.4 - - - 1.8011 - 1.897 0.458 - 325.4 1 2 0 0.0021 10 0 0 0 2.69E+06 1.41E+05 - - - 4.2103 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.11762.11762.2 0.00102 16-Oct K.VGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 911.5804 2.02 37540 11762 2 911.581826 456.7975 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2750.9 - 764645 - - - 1.561 - 2.063 0.231 - 242.9 1 2 0 0.0014 9 0 0 0 7.14E+08 3.53E+08 - - - 2.8418 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.11765.11765.2 1.15 12-Aug K.LEDLIVK[136.11].D "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 836.5099 1.98 37541 11765 2 836.510775 419.2622 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2751.3 - 1.60E+06 - - - 1.0819 - 1.852 0.134 - 160.5 1 2 0 0.0009 7 0 0 0 1.36E+09 6.86E+08 - - - 1.9831 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.11771.11771.2 0.347 16-Nov K.VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 919.5946 2.02 37545 11771 2 919.596197 460.8046 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2752 - 762536 - - - 1.7334 - 2.038 0.247 - 331.7 1 2 0 0.0016 9 0 0 0 7.13E+08 3.53E+08 - - - 2.9246 0.9963 230117_WJC_METTL3_WT_vs_EV_F05.11778.11778.2 0.353 12-Aug K.LEDLIVK.D "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 828.4957 1.98 37547 11778 2 828.497018 415.2551 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2753.1 - 6.67E+06 - - - 1.627 - 1.678 0.073 - 203 1 2 0 0.0013 7 0 0 0 1.36E+09 6.86E+08 - - - 1.2198 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.11780.11780.2 1.23 12-Aug R.LGLTEIR[166.11].K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 810.4839 1.18 37548 11780 2 810.484606 406.2492 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2753.3 - 973059 - - - 0.9044 - 1.694 0.145 - 189.6 1 2 0 0.0007 7 0 0 0 9.99E+08 8.45E+08 - - - 1.7819 0.9823 230117_WJC_METTL3_WT_vs_EV_F05.11783.11783.2 5.59 12-Jul R.LLLPGTR.A sp|Q6P087|RUSD3_HUMAN 1 768.4858 1.46 37549 11783 2 768.487104 385.2502 Mitochondrial mRNA pseudouridine synthase RPUSD3 OS=Homo sapiens OX=9606 GN=RPUSD3 PE=1 SV=3 9.75 2753.7 - 630447 - - - 1.7307 - 1.17 0.077 - 176.7 1 2 0 0.0013 7 0 0 0 4.64E+07 3.18E+07 - - - 0.1068 0.998 230117_WJC_METTL3_WT_vs_EV_F05.11785.11785.2 0.00442 18-Jun K.LITPAVVSER[166.11].L sp|P62851|RS25_HUMAN 1 1093.6371 1.26 37550 11785 2 1093.637581 547.8258 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 6 2753.9 - 135680 - - - 0.459 - 1.352 0.27 - 111.6 1 2 0 0.0005 10 0 0 0 1.26E+07 1.00E+07 - - - 1.8769 0.9939 230117_WJC_METTL3_WT_vs_EV_F05.11789.11789.2 0.63 12-Jul R.LGLTEIR.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 800.4756 1.18 37551 11789 2 800.47664 401.2451 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2754.5 - 2.19E+06 - - - 1.2955 - 1.445 0.084 - 142.6 1 2 0 0.001 7 0 0 0 9.99E+08 8.45E+08 - - - 0.8275 0.9935 230117_WJC_METTL3_WT_vs_EV_F05.11794.11794.2 0.673 12-Jun K.FLEATLR.S "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN" 2 848.4756 0.74 37553 11794 2 848.476395 425.2451 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 6 2755.1 - 371006 - - - 0.9334 - 1.4 0.095 - 106.8 1 2 0 0.0008 7 0 0 0 3.56E+07 4.79E+07 - - - 0.8086 0.9808 230117_WJC_METTL3_WT_vs_EV_F05.11814.11814.2 1.87 12-Jun R.LAVYC[160.03]LK.D "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 865.4732 0.69 37558 11814 2 865.475625 433.7439 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.2 2758.1 - 438359 - - - 2.847 - 1.164 0.115 - 82.1 1 2 0 0.0025 7 0 0 0 3.74E+07 5.38E+07 - - - 0.3708 0.9876 230117_WJC_METTL3_WT_vs_EV_F05.11819.11819.2 1.73 12-Jun K.AFMGPLK.K "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN" 2 762.4098 0.93 37560 11819 2 762.410297 382.2122 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 8.8 2758.7 - 1.15E+06 - - - 0.6099 - 0.94 0.211 - 79.9 1 2 0 0.0005 7 0 0 0 5.62E+07 6.07E+07 - - - 0.4032 0.9745 230117_WJC_METTL3_WT_vs_EV_F05.11823.11823.2 0.201 12-May K.LMPTQWR.T sp|Q99459|CDC5L_HUMAN 1 930.4746 1.16 37561 11823 2 930.474925 466.2446 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.75 2759.3 - 340946 - - - 0.3955 - 1.048 0.124 - 92.3 2 2 0 0.0004 7 0 0 0 4.36E+07 3.77E+07 - - - -0.0292 0.9852 230117_WJC_METTL3_WT_vs_EV_F05.11835.11835.2 0.181 12-Jun K.AFMGPLK[136.11].K "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN" 2 770.424 0.97 37565 11835 2 770.4235 386.2193 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 8.8 2760.9 - 800349 - - - -0.6905 - 1.017 0.225 - 90.2 1 2 0 -0.0005 7 0 0 0 5.54E+07 5.73E+07 - - - 0.7561 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.11837.11837.2 1.03 14-Aug K.LIEQYALR[166.11].E sp|Q9NUQ3|TXLNG_HUMAN 1 1014.5738 1.47 37567 11837 2 1014.57436 508.2942 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2761.1 - 211934 - - - 0.6003 - 1.434 0.172 - 184.3 1 2 0 0.0006 8 0 0 0 3.84E+07 2.60E+07 - - - 1.3984 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.11840.11840.2 0.13 14-Aug K.LIEQYALR.E sp|Q9NUQ3|TXLNG_HUMAN 1 1004.5655 1.47 37568 11840 2 1004.566758 503.29 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2761.5 - 465045 - - - 1.2712 - 1.477 0.216 - 202.9 1 2 0 0.0013 8 0 0 0 3.84E+07 2.60E+07 - - - 1.8122 0.9943 230117_WJC_METTL3_WT_vs_EV_F05.11901.11901.2 1.15 12-Aug K.FVNLYTR[166.11].E "sp|Q15650|TRIP4_HUMAN,tr|H0YL91|H0YL91_HUMAN" 2 921.4948 1.93 37594 11901 2 921.496137 461.7547 Activating signal cointegrator 1 OS=Homo sapiens OX=9606 GN=TRIP4 PE=1 SV=4 8.75 2769.5 - 444948 - - - 1.4813 - 1.244 0.155 - 189.3 1 2 0 0.0014 7 0 0 0 2.22E+07 1.15E+07 - - - 0.8772 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.11909.11909.2 0.108 14/24 R.GGIGAGLGGGLC[160.03]R[166.11].R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1153.5901 0.62 37598 11909 2 1153.592807 577.8023 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2770.6 - 372723 - - - 2.3067 - 2.179 0.336 - 484.8 1 2 0 0.0027 13 0 0 0 9.56E+06 1.53E+07 - - - 3.5208 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.11913.11913.2 0.0137 16-Sep R.LITGLGVGR[166.11].E sp|Q9BQG0|MBB1A_HUMAN 1 894.5526 1.17 37600 11913 2 894.555799 448.2836 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 9.75 2771.1 - 318172 - - - 3.5526 - 1.57 0.303 - 164.7 1 2 0 0.0032 9 0 0 0 1.34E+08 1.15E+08 - - - 2.5829 0.998 230117_WJC_METTL3_WT_vs_EV_F05.11923.11923.2 0.0199 12-Jul R.AAYIYIR[166.11].G "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|B4DE93|B4DE93_HUMAN,tr|E9PJL9|E9PJL9_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PLC6|E9PLC6_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN" 8 878.489 4.9 37606 11923 2 878.490859 440.2518 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.63 2772.3 - 369940 - - - 2.1628 - 1.334 0.259 - 201.2 1 2 0 0.0019 7 0 0 0 1.06E+08 2.16E+07 - - - 1.8665 0.8492 230117_WJC_METTL3_WT_vs_EV_F05.11924.11924.2 0.214 12-Jun L.GNFGEVR.L "sp|P48067|SC6A9_HUMAN,tr|J3KPA5|J3KPA5_HUMAN,tr|B7Z3A9|B7Z3A9_HUMAN,tr|B7Z589|B7Z589_HUMAN" 4 777.377 0.55 37607 11924 2 777.377588 389.6958 Sodium- and chloride-dependent glycine transporter 1 OS=Homo sapiens OX=9606 GN=SLC6A9 PE=1 SV=3 6 2772.4 - 994985 - - - 0.8181 - 1.335 0.233 - 126.4 1 1 0 0.0006 7 0 0 0 9.18E+07 1.67E+08 - - - 1.6772 0.8575 230117_WJC_METTL3_WT_vs_EV_F05.11925.11925.2 0.501 16-Aug H.LLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 996.5604 1818 37608 11925 2 996.562918 499.2875 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 2772.5 - 377999 - - - 2.5317 - 1.745 0.181 - 159.2 1 1 0 0.0025 9 0 0 0 1.91E+09 1.05E+06 - - - 1.9878 0.9547 230117_WJC_METTL3_WT_vs_EV_F05.11953.11953.2 1.67 12-May R.FALVTPK[136.11].K sp|P49792|RBP2_HUMAN 1 782.4782 0.92 37619 11953 2 782.477675 392.2464 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.75 2776.3 - 1.07E+06 - - - -0.6403 - 1.074 0.169 - 63.5 18 2 0 -0.0005 7 0 0 0 5.29E+07 5.72E+07 - - - -0.0455 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.11965.11965.2 0.069 14-Oct R.ALLGPALK.D sp|P35250|RFC2_HUMAN 1 781.5062 1.91 37624 11965 2 781.505421 391.7604 Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3 8.8 2777.9 - 1.57E+06 - - - -0.9648 - 1.673 0.273 - 296.8 1 2 0 -0.0008 8 0 0 0 1.04E+08 5.44E+07 - - - 2.6092 0.9924 230117_WJC_METTL3_WT_vs_EV_F05.11966.11966.2 1.24 14-Aug K.ILVDALQK[136.11].F "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 15 906.563 1.1 37625 11966 2 906.56374 454.2888 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 5.84 2778 - 1.13E+06 - - - 0.8516 - 1.508 0.058 - 168.6 1 2 0 0.0008 8 0 0 0 6.60E+07 5.97E+07 - - - 0.7081 0.9962 230117_WJC_METTL3_WT_vs_EV_F05.11972.11972.2 1.41 14-Jul K.ILVDALQK.F "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 15 898.5488 1.11 37628 11972 2 898.550205 450.2817 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 5.84 2778.7 - 1.56E+06 - - - 1.5992 - 1.394 0.155 - 109.2 1 2 0 0.0014 8 0 0 0 6.52E+07 5.88E+07 - - - 1.1872 0.9933 230117_WJC_METTL3_WT_vs_EV_F05.11978.11978.2 0.922 12-Jul K.VPVNLLR.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 809.5123 1.17 37631 11978 2 809.511983 405.7634 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2779.3 - 506744 - - - -0.42 - 1.23 0.209 - 166.7 1 2 0 -0.0003 7 0 0 0 1.46E+08 1.25E+08 - - - 1.2405 0.9904 230117_WJC_METTL3_WT_vs_EV_F05.11979.11979.2 3.92 12-Aug K.LTELLVK.A "sp|O95470|SGPL1_HUMAN,tr|H0Y3V8|H0Y3V8_HUMAN,tr|H7BXL7|H7BXL7_HUMAN" 3 814.5164 2.64 37632 11979 2 814.518637 408.2655 Sphingosine-1-phosphate lyase 1 OS=Homo sapiens OX=9606 GN=SGPL1 PE=1 SV=3 6 2779.4 - 572730 - - - 2.7403 - 1.392 0.1 - 154.4 1 2 0 0.0022 7 0 0 0 7.38E+07 2.79E+07 - - - 0.8269 1 230117_WJC_METTL3_WT_vs_EV_F05.11982.11982.2 6.72E-05 14/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 21877.15 37633 11982 2 1302.608961 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2779.8 - 7.38E+06 - - - -0.1804 - 2.477 0.542 - 418.4 1 2 0 -0.0002 13 0 0 0 1.79E+09 8.18E+04 - - - 5.3721 0.9894 230117_WJC_METTL3_WT_vs_EV_F05.11983.11983.2 0.365 12-Jun K.VPVNLLR[166.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 819.5206 1.17 37634 11983 2 819.521375 410.7676 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2779.9 - 849063 - - - 0.9542 - 1.258 0.093 - 168.7 1 2 0 0.0008 7 0 0 0 1.46E+08 1.25E+08 - - - 0.4549 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.11990.11990.2 0.000259 20-Aug R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 4695.35 37636 11990 2 1201.608918 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2780.9 - 1.51E+06 - - - -0.1823 - 1.85 0.418 - 74.7 1 2 0 -0.0002 11 0 0 0 6.45E+09 1.37E+06 - - - 3.7925 0.9927 230117_WJC_METTL3_WT_vs_EV_F05.11992.11992.2 1.24 14-Aug R.ALLGPALK[136.11].D sp|P35250|RFC2_HUMAN 1 789.5204 1.91 37638 11992 2 789.519921 395.7675 Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3 8.8 2781.1 - 1.68E+06 - - - -0.575 - 1.36 0.173 - 189.3 1 2 0 -0.0005 8 0 0 0 1.04E+08 5.44E+07 - - - 1.246 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.11993.11993.2 0.173 12-Jul K.IDPLLPK.E sp|Q9BYD6|RM01_HUMAN 1 794.4902 2.52 37639 11993 2 794.490008 398.2524 "39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2" 5.84 2781.2 - 1.38E+06 - - - -0.2303 - 1.335 0.261 - 127.8 1 2 0 -0.0002 7 0 0 0 2.42E+08 9.63E+07 - - - 1.8842 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.12027.12027.2 0.0011 12-Aug R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.67 37651 12027 2 852.483441 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2785.9 - 1.82E+07 - - - -0.251 - 1.54 0.284 - 192.5 1 2 0 -0.0002 7 0 0 0 2.11E+09 1.26E+09 - - - 2.5067 0.9273 230117_WJC_METTL3_WT_vs_EV_F05.12029.12029.2 0.00847 18-Aug R.LVHPGVAEVV.F "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1018.5811 - 37652 12029 2 1018.581536 510.2978 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.24 2786.1 - 390741 - - - 0.3976 - 1.473 0.338 - 145.8 1 1 0 0.0004 10 0 0 0 - - - - - 2.6184 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.12031.12031.2 0.482 14-Jun K.ILFTEATR.L "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 949.5233 1.81 37653 12031 2 949.523686 475.7689 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 6 2786.3 - 1.17E+06 - - - 0.4255 - 1.343 0.293 - 105.2 1 2 0 0.0004 8 0 0 0 4.43E+07 2.45E+07 - - - 2.0944 0.9714 230117_WJC_METTL3_WT_vs_EV_F05.12033.12033.2 1.59 12-Jun K.KWDILGK.S sp|Q86YR7|MF2L2_HUMAN 1 858.4963 335.67 37654 12033 2 858.497068 430.2554 Probable guanine nucleotide exchange factor MCF2L2 OS=Homo sapiens OX=9606 GN=MCF2L2 PE=2 SV=3 8.59 2786.5 - 2.16E+06 - - - 0.8492 - 1.021 0.094 - 129.1 1 2 0 0.0007 7 0 0 0 1.73E+08 5.15E+05 - - - -0.1991 0.9947 230117_WJC_METTL3_WT_vs_EV_F05.12038.12038.3 0.000596 Dec-40 R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 1800.91 37657 12038 3 1201.60869 401.5437 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2787.2 - 2.48E+06 - - - -0.372 - 1.973 0.165 - 232 1 2 0 -0.0004 11 0 0 0 3.72E+08 2.07E+05 - - - 2.31 0.9272 230117_WJC_METTL3_WT_vs_EV_F05.12042.12042.2 0.997 12-Jul K.GLVLMSR.A "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 16 774.4422 1.05 37658 12042 2 774.440183 388.2284 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 9.75 2787.7 - 1.39E+06 - - - -2.598 - 1.556 0.001 - 220.8 1 2 0 -0.002 7 0 0 0 4.28E+08 4.06E+08 - - - 0.4486 0.8644 230117_WJC_METTL3_WT_vs_EV_F05.12061.12061.2 0.0598 14-Aug R.LLASTLVH.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 852.5069 - 37664 12061 2 852.506864 427.2607 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.74 2790.4 - 2.00E+07 - - - -0.0457 - 1.452 0.264 - 184.3 1 1 0 0 8 0 0 0 - - - - - 2.1157 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.12066.12066.2 0.0191 14-Aug R.TFGVSPLR.R sp|Q5T750|XP32_HUMAN 1 875.4865 45.06 37667 12066 2 875.488984 438.7505 Skin-specific protein 32 OS=Homo sapiens OX=9606 GN=XP32 PE=1 SV=1 9.41 2791 - 1.05E+06 - - - 2.835 - 1.488 0.389 - 236.6 1 2 0 0.0025 8 0 0 0 8.00E+07 1.78E+06 - - - 3.112 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.12076.12076.2 0.0623 12-Jul K.MLEYALK.Q "sp|Q13033|STRN3_HUMAN,sp|Q9NRL3|STRN4_HUMAN,sp|O43815|STRN_HUMAN,tr|M0R0P4|M0R0P4_HUMAN,tr|G3V3G7|G3V3G7_HUMAN,tr|F5GYK2|F5GYK2_HUMAN,tr|M0R2A7|M0R2A7_HUMAN,tr|M0QYS2|M0QYS2_HUMAN,tr|M0R0W8|M0R0W8_HUMAN,tr|G3V340|G3V340_HUMAN,tr|M0QXN2|M0QXN2_HUMAN" 11 866.4572 2.27 37670 12076 2 866.456946 434.2359 Striatin-3 OS=Homo sapiens OX=9606 GN=STRN3 PE=1 SV=3 5.75 2792.4 - 929813 - - - -0.2654 - 1.368 0.351 - 153.4 1 2 0 -0.0002 7 0 0 0 3.65E+07 1.61E+07 - - - 2.6263 0.9788 230117_WJC_METTL3_WT_vs_EV_F05.12077.12077.2 0.286 12-Jun R.ILLYAC[160.03]R.N "sp|P36954|RPB9_HUMAN,tr|K7EKS1|K7EKS1_HUMAN" 2 907.495 1.04 37671 12077 2 907.493747 454.7548 DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1 8.22 2792.5 - 438084 - - - -1.3355 - 1.335 0.113 - 120.1 1 2 0 -0.0012 7 0 0 0 6.88E+07 6.62E+07 - - - 0.7907 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.12085.12085.2 0.0235 16-Sep R.NVIEAVYSR[166.11].L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1059.5588 1.34 37675 12085 2 1059.558218 530.7867 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 2793.5 - 351644 - - - -0.5767 - 1.575 0.273 - 251.7 1 2 0 -0.0006 9 0 0 0 6.24E+07 4.64E+07 - - - 2.3714 0.997 230117_WJC_METTL3_WT_vs_EV_F05.12086.12086.2 0.2 14-Jun R.LLEEGVLR.Q "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 927.5389 2.19 37676 12086 2 927.53867 464.7767 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 2793.6 - 379534 - - - -0.2825 - 1.29 0.277 - 81.8 1 2 0 -0.0003 8 0 0 0 1.15E+08 5.22E+07 - - - 1.8548 0.999 230117_WJC_METTL3_WT_vs_EV_F05.12093.12093.2 0.00105 12-Aug R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 2.79 37679 12093 2 844.469466 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2794.5 - 3.14E+07 - - - 0.013 - 1.596 0.308 - 200.2 1 2 0 0 7 0 0 0 4.82E+09 1.72E+09 - - - 2.7972 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.12095.12095.2 0.00436 16-Aug K.LVPVGYGIK[136.11].K sp|P24534|EF1B_HUMAN 1 952.5837 0.72 37680 12095 2 952.584499 477.2991 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2794.7 - 1.05E+06 - - - 0.8346 - 1.333 0.477 - 185.9 1 2 0 0.0008 9 0 0 0 1.13E+09 1.57E+09 - - - 3.3954 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.12097.12097.2 0.0318 14-Jul R.VFVSPLAK[136.11].K "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 867.5309 0.75 37682 12097 2 867.530406 434.7727 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 8.72 2794.9 - 1.02E+06 - - - -0.6155 - 1.427 0.227 - 150.6 1 2 0 -0.0005 8 0 0 0 2.81E+08 3.74E+08 - - - 1.7899 0.9661 230117_WJC_METTL3_WT_vs_EV_F05.12101.12101.2 0.662 12-Jun K.LFVIAQK.L sp|Q9Y3A2|UTP11_HUMAN 1 817.5062 5.08 37684 12101 2 817.504951 409.7604 Probable U3 small nucleolar RNA-associated protein 11 OS=Homo sapiens OX=9606 GN=UTP11 PE=1 SV=2 8.75 2795.5 - 1.36E+06 - - - -1.4972 - 1.285 0.093 - 82.2 1 2 0 -0.0012 7 0 0 0 1.47E+08 2.90E+07 - - - 0.5221 0.9805 230117_WJC_METTL3_WT_vs_EV_F05.12104.12104.2 0.522 12-Jul K.IPVIIER.Y "sp|A6NCE7|MP3B2_HUMAN,sp|Q9GZQ8|MLP3B_HUMAN,sp|Q9H492|MLP3A_HUMAN,tr|H3BTL1|H3BTL1_HUMAN" 4 838.5276 1.34 37686 12104 2 838.529364 420.2711 Microtubule-associated proteins 1A\1B light chain 3 beta 2 OS=Homo sapiens OX=9606 GN=MAP1LC3B2 PE=2 SV=1 6 2795.9 - 850270 - - - 2.0572 - 1.438 0.006 - 186.7 2 2 0 0.0017 7 0 0 0 4.76E+07 3.55E+07 - - - 0.1013 0.9 230117_WJC_METTL3_WT_vs_EV_F05.12125.12125.2 0.117 12-Jul Y.LFGC[160.03]ELK[136.11].A "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 9 873.451 1.17 37696 12125 2 873.451621 437.7328 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 5.99 2798.3 - 798495 - - - 0.7396 - 1.185 0.345 - 108.1 1 1 0 0.0006 7 0 0 0 9.04E+07 7.73E+07 - - - 2.1268 0.9496 230117_WJC_METTL3_WT_vs_EV_F05.12144.12144.2 0.665 12-Jul R.FAAVIMR.L "sp|Q6SJ96|TBPL2_HUMAN,sp|P20226|TBP_HUMAN,tr|Q7Z6S5|Q7Z6S5_HUMAN,tr|A0A1B0GVC6|A0A1B0GVC6_HUMAN,tr|Q32MN6|Q32MN6_HUMAN" 5 806.4473 3.08 37698 12144 2 806.452003 404.2309 TATA box-binding protein-like 2 OS=Homo sapiens OX=9606 GN=TBPL2 PE=2 SV=1 9.75 2801.4 - 1.27E+06 - - - 5.8566 - 1.553 0.091 - 128.4 1 2 0 0.0047 7 0 0 0 7.18E+07 2.33E+07 - - - 1.1064 0.9144 230117_WJC_METTL3_WT_vs_EV_F05.12155.12155.2 0.00254 12-Jul R.PVWADYR[166.11].R "sp|Q9Y676|RT18B_HUMAN,tr|A0A0G2JIC6|A0A0G2JIC6_HUMAN" 2 915.4478 1.29 37699 12155 2 915.44976 458.7312 "28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1" 6.26 2803.2 - 944668 - - - 2.117 - 1.287 0.342 - 207.1 1 1 0 0.0019 7 0 0 0 4.81E+07 3.74E+07 - - - 2.3659 1 230117_WJC_METTL3_WT_vs_EV_F05.12172.12172.3 5.44E-08 15/56 K.KVPQVSTPTLVEVSR.N "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1638.9305 17.68 37705 12172 3 1638.933252 547.3174 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 8.75 2805.5 - 569429 - - - 1.6968 - 3.125 0.536 - 360.6 1 2 0 0.0028 15 0 0 0 1.78E+07 1.01E+06 - - - 7.4883 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.12177.12177.2 0.0126 16-Sep K.LVPVGYGIK.K sp|P24534|EF1B_HUMAN 1 944.5695 0.72 37708 12177 2 944.569784 473.292 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2806.1 - 1.73E+07 - - - 0.2964 - 1.546 0.449 - 372.4 1 2 0 0.0003 9 0 0 0 1.13E+09 1.57E+09 - - - 3.6176 0.9953 230117_WJC_METTL3_WT_vs_EV_F05.12181.12181.2 0.192 12-Jul K.LSIVPVR[166.11].R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 792.5097 0.88 37710 12181 2 792.509359 397.2621 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2806.6 - 2.00E+07 - - - -0.4227 - 1.487 0.166 - 167.9 1 2 0 -0.0003 7 0 0 0 2.50E+09 2.85E+09 - - - 1.5241 0.9854 230117_WJC_METTL3_WT_vs_EV_F05.12187.12187.2 0.514 12-Jun K.YLYEIAR.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 926.4862 99.83 37714 12187 2 926.485186 464.2504 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6 2807.3 - 1.11E+06 - - - -1.0599 - 1.203 0.178 - 87.1 1 2 0 -0.001 7 0 0 0 7.82E+08 7.84E+06 - - - 0.941 0.9964 230117_WJC_METTL3_WT_vs_EV_F05.12193.12193.2 0.287 12-Aug K.LSIVPVR.R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 782.5014 0.87 37716 12193 2 782.501281 392.258 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2808.1 - 2.58E+07 - - - -0.1827 - 1.579 0.156 - 241.5 1 2 0 -0.0001 7 0 0 0 2.49E+09 2.85E+09 - - - 1.6405 0.9946 230117_WJC_METTL3_WT_vs_EV_F05.12194.12194.2 0.326 14-Jul K.IIGDTFVK.L sp|P49915|GUAA_HUMAN 1 891.5066 2.47 37717 12194 2 891.507345 446.7606 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.84 2808.1 - 1.16E+06 - - - 0.8704 - 1.251 0.167 - 105.2 1 2 0 0.0008 8 0 0 0 2.73E+08 1.11E+08 - - - 0.9496 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.12200.12200.2 0.0766 14-Jul K.TPVIVTLK[136.11].E "sp|Q9Y4L1|HYOU1_HUMAN,tr|A0A087WWI4|A0A087WWI4_HUMAN,tr|K7EQK2|K7EQK2_HUMAN,tr|A0A087WW13|A0A087WW13_HUMAN,tr|Q9BST8|Q9BST8_HUMAN,tr|J3KTF1|J3KTF1_HUMAN,tr|A0A494C039|A0A494C039_HUMAN,tr|J3QL06|J3QL06_HUMAN,tr|A0A087X214|A0A087X214_HUMAN,tr|A0A087X054|A0A087X054_HUMAN,tr|E9PJ21|E9PJ21_HUMAN,tr|J3QLE9|J3QLE9_HUMAN,tr|J3QQH7|J3QQH7_HUMAN" 13 877.5728 1.38 37719 12200 2 877.574741 439.7937 Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1 8.41 2808.9 - 341142 - - - 2.2061 - 1.396 0.228 - 96.3 1 2 0 0.0019 8 0 0 0 1.34E+07 9.67E+06 - - - 1.7306 0.9947 230117_WJC_METTL3_WT_vs_EV_F05.12202.12202.2 0.00322 20-Sep R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 83.51 37720 12202 2 1264.625375 633.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2809.1 - 408404 - - - -3.6034 - 1.891 0.392 - 181.1 1 2 0 -0.0046 11 0 0 0 2.18E+07 2.61E+05 - - - 3.6584 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.12231.12231.2 0.00126 16-Jul K.VLEGMEVVR[166.11].K "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1040.5564 0.14 37728 12231 2 1040.558576 521.2855 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.53 2813.5 - 318781 - - - 2.1046 - 1.605 0.26 - 158.2 1 2 0 0.0022 9 0 0 0 6.89E+06 5.00E+07 - - - 2.3294 0.9954 230117_WJC_METTL3_WT_vs_EV_F05.12247.12247.2 0.296 12-Jul K.GVTLGFR[166.11].Y "sp|P32969|RL9_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 4 758.4314 0.001 37733 12247 2 758.431751 380.223 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 9.75 2815.8 - 2.40E+06 - - - 0.4048 - 1.512 0.114 - 233.5 1 2 0 0.0003 7 0 0 0 0.00E+00 8.87E+07 - - - 1.1929 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.12249.12249.2 0.000655 12-Aug R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.44 37734 12249 2 852.483544 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2816 - 5.79E+07 - - - -0.1302 - 1.586 0.31 - 204.9 1 2 0 -0.0001 7 0 0 0 8.37E+09 5.80E+09 - - - 2.792 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.12303.12303.2 0.00128 20-Sep R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 64.91 37764 12303 2 1201.611569 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2823 - 346756 - - - 2.024 - 1.939 0.442 - 194.4 1 2 0 0.0024 11 0 0 0 3.40E+07 5.24E+05 - - - 4.0962 0.8668 230117_WJC_METTL3_WT_vs_EV_F05.12307.12307.2 0.272 12-Jul F.ILEVYYK[136.11].S sp|A8MTT3|CEBOS_HUMAN 1 934.5255 4.74 37766 12307 2 934.526655 468.27 Protein CEBPZOS OS=Homo sapiens OX=9606 GN=CEBPZOS PE=1 SV=2 6 2823.5 - 748761 - - - 1.2145 - 1.317 0.249 - 129 1 1 0 0.0011 7 0 0 0 1.22E+08 2.57E+07 - - - 1.7522 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.12308.12308.2 0.0542 14-Aug R.LADIVVPR.G sp|Q9NWZ5|UCKL1_HUMAN 1 881.5335 4.17 37767 12308 2 881.534641 441.774 Uridine-cytidine kinase-like 1 OS=Homo sapiens OX=9606 GN=UCKL1 PE=1 SV=2 5.84 2823.7 - 455069 - - - 1.3488 - 1.945 0.33 - 195.9 1 2 0 0.0012 8 0 0 0 1.43E+07 3.43E+06 - - - 3.4844 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.12316.12316.2 0.0132 12-Aug R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.05 37772 12316 2 844.471046 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2824.7 - 2.47E+07 - - - 1.884 - 1.309 0.301 - 199 1 2 0 0.0016 7 0 0 0 5.62E+09 5.33E+09 - - - 2.1169 0.8942 230117_WJC_METTL3_WT_vs_EV_F05.12327.12327.2 0.117 14-Jul A.LLPALAAR[166.11].G "sp|P46531|NOTC1_HUMAN,sp|Q86Y56|DAAF5_HUMAN,sp|P08582|TRFM_HUMAN,tr|A0A7P0T8U6|A0A7P0T8U6_HUMAN,tr|A0A7P0TAK8|A0A7P0TAK8_HUMAN,tr|A0A7P0TB20|A0A7P0TB20_HUMAN,tr|A0A7P0T8W1|A0A7P0T8W1_HUMAN,tr|A0A7P0Z4H9|A0A7P0Z4H9_HUMAN,tr|A0A7P0T9V1|A0A7P0T9V1_HUMAN,tr|A0A7P0TBG2|A0A7P0TBG2_HUMAN" 10 833.5362 1.28 37777 12327 2 833.536836 417.7754 Neurogenic locus notch homolog protein 1 OS=Homo sapiens OX=9606 GN=NOTCH1 PE=1 SV=4 9.75 2826.2 - 791961 - - - 0.7114 - 1.298 0.304 - 135.6 1 1 0 0.0006 8 0 0 0 4.02E+07 3.15E+07 - - - 2.0728 0.962 230117_WJC_METTL3_WT_vs_EV_F05.12328.12328.2 0.055 16-Sep R.PLISVYSEK[136.11].G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1042.579 0.78 37778 12328 2 1042.579637 522.2968 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.42 2826.3 - 426590 - - - 0.5995 - 1.786 0.365 - 311.1 1 1 0 0.0006 9 0 0 0 4.14E+07 5.31E+07 - - - 3.4146 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.12345.12345.2 0.181 14-Aug K.LIGEYGLR.N "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 919.5127 0.81 37784 12345 2 919.513897 460.7636 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 2828.7 - 1.55E+06 - - - 1.2833 - 1.519 0.232 - 153.4 1 2 0 0.0012 8 0 0 0 2.42E+09 3.01E+09 - - - 2.015 0.9956 230117_WJC_METTL3_WT_vs_EV_F05.12352.12352.2 1.16 12-Jul R.LLSVNIR.V sp|P07814|SYEP_HUMAN 1 813.5072 1.47 37786 12352 2 813.507735 407.7609 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 9.75 2829.7 - 820199 - - - 0.6109 - 1.474 0.121 - 129.8 1 2 0 0.0005 7 0 0 0 2.11E+08 1.44E+08 - - - 1.1639 0.8498 230117_WJC_METTL3_WT_vs_EV_F05.12359.12359.2 36.4 14-Jun K.IFEGLGPK.V "sp|O75376|NCOR1_HUMAN,tr|E7EVU5|E7EVU5_HUMAN,tr|J3KS51|J3KS51_HUMAN,tr|E7EW50|E7EW50_HUMAN,tr|A0A088AWL3|A0A088AWL3_HUMAN" 5 859.4804 1.07 37789 12359 2 859.481262 430.7475 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 6 2830.7 - 540448 - - - 1.0565 - 0.912 0.006 - 68.8 2 2 0 0.0009 8 0 0 0 2.54E+07 2.36E+07 - - - -1.3273 0.9704 230117_WJC_METTL3_WT_vs_EV_F05.12362.12362.2 3.52 16-Jun R.LLGTLAVSR[166.11].G "sp|Q96MI6|PPM1M_HUMAN,tr|H7C3K4|H7C3K4_HUMAN,tr|H7C3S3|H7C3S3_HUMAN" 3 938.5788 1.28 37791 12362 2 938.581165 470.2967 Protein phosphatase 1M OS=Homo sapiens OX=9606 GN=PPM1M PE=2 SV=2 9.75 2831 - 169607 - - - 2.4814 - 1.061 0.099 - 67.9 1 2 0 0.0023 9 0 0 0 8.03E+06 6.27E+06 - - - -0.0572 0.9293 230117_WJC_METTL3_WT_vs_EV_F05.12369.12369.2 0.0025 16-Oct R.PLISVYSEK.G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1034.5648 0.78 37795 12369 2 1034.568446 518.2897 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.42 2831.8 - 1.02E+06 - - - 3.5126 - 1.713 0.415 - 372 1 1 0 0.0036 9 0 0 0 4.13E+07 5.29E+07 - - - 3.6622 0.9378 230117_WJC_METTL3_WT_vs_EV_F05.12404.12404.2 3.74 12-May K.VLPIIQR[166.11].W "sp|Q9BYW2|SETD2_HUMAN,tr|H7C3H4|H7C3H4_HUMAN,tr|A0A1W2PPX9|A0A1W2PPX9_HUMAN" 3 847.5519 1.72 37804 12404 2 847.552977 424.7832 Histone-lysine N-methyltransferase SETD2 OS=Homo sapiens OX=9606 GN=SETD2 PE=1 SV=3 9.72 2837.1 - 294660 - - - 1.279 - 0.947 0.082 - 58.7 3 2 0 0.0011 7 0 0 0 2.72E+07 1.58E+07 - - - -0.7394 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.12405.12405.2 0.00942 20-Jul R.QSVEADINGLR.R "sp|P13645|K1C10_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 7 1200.6099 3.92 37805 12405 2 1200.609969 601.3122 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 2837.2 - 159862 - - - 0.0866 - 1.539 0.213 - 77 1 2 0 0.0001 11 0 0 0 1.01E+07 2.57E+06 - - - 1.7805 0.996 230117_WJC_METTL3_WT_vs_EV_F05.12408.12408.2 0.00236 18-Sep K.DVNAAIATIK.T "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 8 1014.571 5.54 37806 12408 2 1014.567891 508.2928 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 5.84 2837.6 - 254893 - - - -3.0249 - 1.747 0.417 - 133.7 2 2 0 -0.0031 10 0 0 0 1.77E+07 3.20E+06 - - - 3.5428 0.992 230117_WJC_METTL3_WT_vs_EV_F05.12410.12410.2 0.158 12-Aug R.IGTFDLK[136.11].Y "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN" 2 800.4524 0.45 37807 12410 2 800.4528 401.2335 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 5.84 2837.9 - 823409 - - - 0.5559 - 1.335 0.104 - 147.7 1 2 0 0.0004 7 0 0 0 2.21E+07 4.91E+07 - - - 0.7245 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.12411.12411.2 0.0548 14-Aug R.LPLQDVYK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 974.5437 5.12 37808 12411 2 974.544173 488.2791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2838 - 221681 - - - 0.5028 - 1.497 0.253 - 173.6 1 2 0 0.0005 8 0 0 0 2.37E+09 4.64E+08 - - - 2.1263 0.9811 230117_WJC_METTL3_WT_vs_EV_F05.12419.12419.2 1.24 14-Jun K.AGLYGLPR[166.11].R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|A0A0U1RRG3|A0A0U1RRG3_HUMAN" 3 855.4842 2.29 37813 12419 2 855.484617 428.7494 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.79 2839 - 533371 - - - 0.4781 - 1.032 0.137 - 80.7 1 2 0 0.0004 8 0 0 0 3.97E+08 1.74E+08 - - - 0.1478 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.12434.12434.4 5.44E-05 16/108 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 3.09 37819 12434 4 2080.026791 521.0129 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2840.9 - 828840 - - - 2.0471 - 1.868 0.434 - 47.2 1 2 0 0.0043 19 0 0 0 3.06E+07 9.90E+06 - - - 3.2137 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.12437.12437.2 0.0434 12-Jun K.TC[160.03]PLLLR.V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 871.495 1.25 37821 12437 2 871.494151 436.7548 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2841.2 - 1.04E+06 - - - -0.9271 - 1.378 0.347 - 164.3 1 2 0 -0.0008 7 0 0 0 1.23E+09 9.87E+08 - - - 2.6196 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.12439.12439.2 0.347 12-Jul K.FASFIDK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YHD9|H0YHD9_HUMAN,tr|F8W1S1|F8W1S1_HUMAN,tr|F8VS61|F8VS61_HUMAN" 26 826.4225 61.93 37823 12439 2 826.423661 414.2185 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 5.84 2841.4 - 1.05E+06 - - - 1.3988 - 1.658 0.157 - 121.5 1 2 0 0.0012 7 0 0 0 9.54E+08 1.54E+07 - - - 1.8023 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.12461.12461.3 1.00E-05 Dec-72 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 36.7 37834 12461 3 2080.027637 694.3481 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2844.2 - 311392 - - - 2.4538 - 2.12 0.467 - 33.5 1 2 0 0.0051 19 0 0 0 7.16E+07 1.95E+06 - - - 5.5913 0.9739 230117_WJC_METTL3_WT_vs_EV_F05.12467.12467.2 0.601 18-May R.TIAQDYGVLK.A "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1106.5972 1.84 37838 12467 2 1106.600622 554.3059 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.5 2844.9 - 107296 - - - 3.115 - 0.957 0.183 - 57.3 1 2 0 0.0034 10 0 0 0 1.15E+07 6.25E+06 - - - 0.2689 0.9234 230117_WJC_METTL3_WT_vs_EV_F05.12471.12471.3 0.0739 Jul-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 32.22 37840 12471 3 2088.049738 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2845.6 - 95715.6 - - - 6.2283 - 1.275 0.249 - 19.8 1 2 0 0.013 19 0 0 0 6.28E+07 1.95E+06 - - - 1.9094 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.12491.12491.2 0.05 12-Aug R.WLGEPIK[136.11].A "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 849.484 0.46 37847 12491 2 849.487153 425.7493 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6 2848.2 - 2.60E+06 - - - 3.7234 - 1.365 0.392 - 291 1 2 0 0.0032 7 0 0 0 1.15E+09 2.49E+09 - - - 2.9212 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.12508.12508.2 0.0156 14-Aug R.LPLQDVYK[136.11].L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 982.5579 5.09 37852 12508 2 982.558977 492.2862 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2850.7 - 4.82E+06 - - - 1.1134 - 1.761 0.335 - 264.6 1 2 0 0.0011 8 0 0 0 2.36E+09 4.64E+08 - - - 3.2216 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.12513.12513.2 0.257 12-Sep R.WLGEPIK.A "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 841.4698 0.45 37853 12513 2 841.470944 421.7422 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6 2851.5 - 5.24E+06 - - - 1.3714 - 1.456 0.313 - 415.9 1 2 0 0.0012 7 0 0 0 1.12E+09 2.48E+09 - - - 2.5429 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.12514.12514.2 0.000191 16-Aug R.LYEALTPVH.- "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1041.5495 - 37854 12514 2 1041.552439 521.782 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.24 2851.6 - 317516 - - - 2.8256 - 1.525 0.4 - 156 1 2 0 0.0029 9 0 0 0 - - - - - 3.2153 0.9928 230117_WJC_METTL3_WT_vs_EV_F05.12530.12530.2 0.155 14-Jul K.IPYTTVLR.L "sp|Q08945|SSRP1_HUMAN,tr|E9PMD4|E9PMD4_HUMAN" 2 961.5597 0.26 37860 12530 2 961.561884 481.7871 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 8.75 2853.6 - 344866 - - - 2.3056 - 1.278 0.148 - 145 1 2 0 0.0022 8 0 0 0 1.18E+08 4.46E+08 - - - 0.8732 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.12537.12537.2 0.0204 12-May R.LVVFDAR[166.11].- sp|P53803|RPAB4_HUMAN 1 828.4733 1.01 37862 12537 2 828.47397 415.2439 "DNA-directed RNA polymerases I, II, and III subunit RPABC4 OS=Homo sapiens OX=9606 GN=POLR2K PE=1 SV=1" 5.84 2854.6 - 5.19E+06 - - - 0.7991 - 1.274 0.307 - 94.3 1 2 0 0.0007 7 0 0 0 3.16E+08 3.12E+08 - - - 2.0756 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.12538.12538.2 0.000166 20-Sep R.TAAENDFVTLK.K sp|P35908|K22E_HUMAN 1 1207.6085 12.74 37863 12538 2 1207.608531 604.8115 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2854.7 - 103385 - - - 0.0522 - 1.866 0.446 - 187.4 1 2 0 0.0001 11 0 0 0 4.96E+06 3.90E+05 - - - 4.0227 0.9131 230117_WJC_METTL3_WT_vs_EV_F05.12544.12544.2 0.0148 14-Jun L.VDHALIAR[166.11].C sp|Q05BV3|EMAL5_HUMAN 1 903.5166 4.1 37865 12544 2 903.518534 452.7656 Echinoderm microtubule-associated protein-like 5 OS=Homo sapiens OX=9606 GN=EML5 PE=2 SV=3 6.71 2855.6 - 829955 - - - 2.1737 - 1.406 0.312 - 144.3 1 1 0 0.002 8 0 0 0 1.73E+08 4.22E+07 - - - 2.3725 0.9555 230117_WJC_METTL3_WT_vs_EV_F05.12553.12553.2 0.595 16-Jul K.AGLAPLEVR.V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 924.5393 0.85 37868 12553 2 924.538507 463.2769 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.05 2856.8 - 328636 - - - -0.8209 - 1.299 0.051 - 108.2 2 2 0 -0.0008 9 0 0 0 9.28E+07 1.10E+08 - - - 0.0398 0.998 230117_WJC_METTL3_WT_vs_EV_F05.12573.12573.2 0.108 16-Sep K.AGLAPLEVR[166.11].V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 934.5475 1.05 37877 12573 2 934.547685 468.281 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.05 2859.2 - 274871 - - - 0.1594 - 1.566 0.227 - 191.7 1 2 0 0.0001 9 0 0 0 7.63E+07 7.29E+07 - - - 2.0152 0.9944 230117_WJC_METTL3_WT_vs_EV_F05.12585.12585.2 0.476 16-Jun K.LVPVGYGIR[166.11].K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 982.5839 0.93 37883 12585 2 982.585091 492.2992 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2860.8 - 4.11E+06 - - - 1.1897 - 1.159 0.192 - 101.7 1 2 0 0.0012 9 0 0 0 7.49E+08 8.08E+08 - - - 0.8856 0.8506 230117_WJC_METTL3_WT_vs_EV_F05.12586.12586.2 0.213 12-Aug L.PLQDVYK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 861.4596 3.29 37884 12586 2 861.459877 431.7371 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.26 2860.9 - 656604 - - - 0.2995 - 1.233 0.29 - 185.6 1 1 0 0.0003 7 0 0 0 2.48E+07 7.54E+06 - - - 1.8465 0.9935 230117_WJC_METTL3_WT_vs_EV_F05.12596.12596.2 0.0192 12-Jul R.FAAFIDK.V "sp|Q14533|KRT81_HUMAN,sp|P78386|KRT85_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|U3KPR1|U3KPR1_HUMAN" 6 810.4276 112.04 37888 12596 2 810.427682 406.2211 "Keratin, type II cuticular Hb1 OS=Homo sapiens OX=9606 GN=KRT81 PE=1 SV=3" 5.84 2862.2 - 2.28E+06 - - - 0.1135 - 1.412 0.121 - 134.6 1 2 0 0.0001 7 0 0 0 9.28E+07 8.28E+05 - - - 1.0279 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.12605.12605.2 0.00377 16-Sep K.IGPLGLSPK.K sp|P30050|RL12_HUMAN 1 880.5382 1.63 37891 12605 2 880.538217 441.2764 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2863.5 - 9.22E+06 - - - 0.0159 - 1.738 0.336 - 215.5 1 2 0 0 9 0 0 0 1.16E+10 7.11E+09 - - - 3.1218 0.995 230117_WJC_METTL3_WT_vs_EV_F05.12610.12610.2 0.433 12-Aug R.LAILYAK.R "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 790.4953 1.17 37893 12610 2 790.495783 396.2549 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 8.59 2864.1 - 992563 - - - 0.6414 - 1.699 0.046 - 194.7 1 2 0 0.0005 7 0 0 0 2.34E+08 2.01E+08 - - - 1.0601 0.9948 230117_WJC_METTL3_WT_vs_EV_F05.12615.12615.2 0.299 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 176.37 37895 12615 2 776.382259 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2864.7 - 1.56E+06 - - - 0.7161 - 1.308 0.151 - 159.9 1 2 0 0.0006 7 0 0 0 1.06E+09 6.00E+06 - - - 1.0069 0.9833 230117_WJC_METTL3_WT_vs_EV_F05.12617.12617.2 0.0243 16-Aug K.LVPVGYGIR.K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 972.5757 0.93 37896 12617 2 972.575665 487.2951 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2864.9 - 1.28E+07 - - - 0.0134 - 1.235 0.098 - 225.4 1 2 0 0 9 0 0 0 7.53E+08 8.08E+08 - - - 0.3755 0.9896 230117_WJC_METTL3_WT_vs_EV_F05.12635.12635.2 0.963 12-Aug R.TLQVLIK.Q "sp|Q7Z3B4|NUP54_HUMAN,sp|P35219|CAH8_HUMAN" 2 813.5324 2.39 37901 12635 2 813.532165 407.7735 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.41 2867.4 - 2.82E+06 - - - -0.2766 - 1.438 0.087 - 228.4 1 2 0 -0.0002 7 0 0 0 1.67E+08 6.98E+07 - - - 0.8345 0.9778 230117_WJC_METTL3_WT_vs_EV_F05.12666.12666.2 0.646 20-Jun R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 999 37913 12666 2 1068.659126 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 2871.5 - 4.38E+06 - - - 4.5197 - 1.396 0.18 - 81.8 3 2 0 0.0048 11 0 0 0 6.37E+08 0.00E+00 - - - 1.0583 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.12677.12677.2 0.00552 14-Sep K.FGGVVELR.M sp|P49247|RPIA_HUMAN 1 875.4865 1.17 37916 12677 2 875.486209 438.7505 Ribose-5-phosphate isomerase OS=Homo sapiens OX=9606 GN=RPIA PE=1 SV=3 6 2873.1 - 1.62E+06 - - - -0.3347 - 1.91 0.303 - 251.6 1 2 0 -0.0003 8 0 0 0 2.15E+08 1.83E+08 - - - 3.2305 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.12686.12686.2 0.181 12-Jul R.LVNQWIK[136.11].Q "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 907.5371 1.19 37920 12686 2 907.537321 454.7758 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 8.75 2874.3 - 1.15E+06 - - - 0.2567 - 1.313 0.357 - 123.9 1 2 0 0.0002 7 0 0 0 4.34E+07 3.65E+07 - - - 2.5406 0.9541 230117_WJC_METTL3_WT_vs_EV_F05.12690.12690.4 0.118 Sep-96 T.LLLIILTDVFIISTVLR.L sp|Q8NGY0|O10X1_HUMAN 1 1941.2278 40.82 37921 12690 4 1941.229554 486.3142 Olfactory receptor 10X1 OS=Homo sapiens OX=9606 GN=OR10X1 PE=3 SV=2 5.84 2874.9 - 2.20E+06 - - - 0.8922 - 1.257 0.278 - 19.5 1 1 0 0.0017 17 0 0 0 9.09E+07 2.23E+06 - - - 1.7246 0.9913 230117_WJC_METTL3_WT_vs_EV_F05.12691.12691.2 5.64 14-Sep R.LPVDIAYK.R sp|P15924|DESP_HUMAN 1 917.5222 6.52 37922 12691 2 917.520727 459.7684 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.83 2875 - 1.24E+06 - - - -1.6261 - 1.567 0.17 - 262.3 1 2 0 -0.0015 8 0 0 0 2.95E+08 4.52E+07 - - - 1.6508 0.9936 230117_WJC_METTL3_WT_vs_EV_F05.12695.12695.2 0.00923 14-Sep K.FGELVMTK.E "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 923.4786 3 37924 12695 2 923.476521 462.7466 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6 2875.5 - 1.33E+06 - - - -2.2946 - 1.377 0.318 - 220.8 1 2 0 -0.0021 8 0 0 0 1.72E+08 5.74E+07 - - - 2.3539 0.9937 230117_WJC_METTL3_WT_vs_EV_F05.12701.12701.2 0.00166 18-Nov R.RVLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1125.687 1.26 37927 12701 2 1125.692063 563.8508 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2876.2 - 486462 - - - 4.5039 - 1.915 0.175 - 435.8 1 2 0 0.0051 10 0 0 0 3.59E+07 2.86E+07 - - - 2.1455 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.12710.12710.2 0.262 14-Sep K.TALLGLTK[136.11].T sp|Q9BTZ2|DHRS4_HUMAN 1 823.5259 0.92 37931 12710 2 823.5259 412.7702 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 8.41 2877.4 - 1.11E+07 - - - 0.0559 - 1.537 0.199 - 343.1 1 2 0 0 8 0 0 0 6.62E+08 7.16E+08 - - - 1.8072 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.12719.12719.2 0.00183 18-Sep R.VLTAVEMGMK.N sp|Q9BVS4|RIOK2_HUMAN 1 1077.5562 2.58 37935 12719 2 1077.556745 539.7854 Serine\threonine-protein kinase RIO2 OS=Homo sapiens OX=9606 GN=RIOK2 PE=1 SV=2 5.97 2878.5 - 244852 - - - 0.4705 - 1.765 0.377 - 172.7 1 2 0 0.0005 10 0 0 0 3.33E+06 1.29E+06 - - - 3.4112 0.9962 230117_WJC_METTL3_WT_vs_EV_F05.12722.12722.2 0.00478 14-Aug K.FGELVMTK[136.11].E "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 931.4928 3.05 37936 12722 2 931.493401 466.7537 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6 2878.9 - 1.35E+06 - - - 0.6023 - 1.391 0.169 - 160 1 2 0 0.0006 8 0 0 0 1.78E+08 5.82E+07 - - - 1.2844 0.998 230117_WJC_METTL3_WT_vs_EV_F05.12727.12727.2 0.272 14-Aug K.SALALAIK[136.11].V "sp|P25789|PSA4_HUMAN,tr|H0YKS0|H0YKS0_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 8 793.5153 1.47 37938 12727 2 793.514681 397.7649 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 8.47 2879.6 - 3.50E+06 - - - -0.7675 - 1.54 0.298 - 178.5 1 2 0 -0.0006 8 0 0 0 4.06E+08 2.76E+08 - - - 2.5441 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.12746.12746.2 0.0249 18-Oct R.ISGLIYEETR[166.11].G sp|P62805|H4_HUMAN 1 1189.6218 0.67 37946 12746 2 1189.623461 595.8182 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2882.2 - 252221 - - - 1.3769 - 2.05 0.354 - 314.2 1 2 0 0.0016 10 0 0 0 7.38E+06 1.10E+07 - - - 3.6588 0.9959 230117_WJC_METTL3_WT_vs_EV_F05.12749.12749.2 0.221 12-Jul K.LYALDVR.V "sp|O94913|PCF11_HUMAN,tr|E9PKN0|E9PKN0_HUMAN,tr|E9PQF9|E9PQF9_HUMAN,tr|E9PQ01|E9PQ01_HUMAN" 4 848.4756 0.7 37947 12749 2 848.477781 425.2451 Pre-mRNA cleavage complex 2 protein Pcf11 OS=Homo sapiens OX=9606 GN=PCF11 PE=1 SV=3 5.84 2882.6 - 410003 - - - 2.567 - 1.415 0.172 - 134.9 1 2 0 0.0022 7 0 0 0 1.62E+07 2.29E+07 - - - 1.4106 0.998 230117_WJC_METTL3_WT_vs_EV_F05.12760.12760.4 0.00258 12/198 R.SDSPVPTAPTSGGPKPSTASAVPELATDPELEKK.L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3360.6937 999 37953 12760 4 3360.700168 841.1807 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2884.1 - 912078 - - - 1.9362 - 2.291 0.323 - 52.3 1 2 0 0.0065 34 0 0 0 1.21E+07 0.00E+00 - - - 2.2828 0.9782 230117_WJC_METTL3_WT_vs_EV_F05.12761.12761.2 0.789 14-Jun R.VAELMVYR[166.11].E sp|O43156|TTI1_HUMAN 1 989.5244 0.62 37954 12761 2 989.523618 495.7695 TELO2-interacting protein 1 homolog OS=Homo sapiens OX=9606 GN=TTI1 PE=1 SV=3 5.97 2884.2 - 117495 - - - -0.7478 - 1.268 0.101 - 81 1 2 0 -0.0007 8 0 0 0 2.86E+06 4.60E+06 - - - 0.5029 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.12764.12764.2 0.0029 18-Oct R.ISGLIYEETR.G sp|P62805|H4_HUMAN 1 1179.6136 0.67 37955 12764 2 1179.612438 590.8141 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2884.6 - 271821 - - - -0.9452 - 2.211 0.414 - 296.1 1 2 0 -0.0011 10 0 0 0 7.38E+06 1.10E+07 - - - 4.3132 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.12771.12771.3 0.00163 Sep-36 R.LVNHFVEEFK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1260.6503 15.87 37957 12771 3 1260.652756 421.224 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2885.6 - 2.79E+06 - - - 1.9696 - 1.795 0.346 - 114.8 1 2 0 0.0025 10 0 0 0 1.42E+08 8.98E+06 - - - 4.1053 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.12787.12787.2 0.0701 14-Jul K.QVEELFER[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1058.5272 2.2 37966 12787 2 1058.529437 530.2709 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2887.7 - 258998 - - - 2.118 - 1.427 0.17 - 230 1 2 0 0.0022 8 0 0 0 2.33E+07 1.06E+07 - - - 1.3683 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.12792.12792.2 0.00916 18-Sep R.LGPSVVGLAR.Y "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 967.5815 1.41 37969 12792 2 967.583809 484.798 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 9.75 2888.4 - 601978 - - - 2.4225 - 1.846 0.286 - 237.5 1 2 0 0.0023 10 0 0 0 7.59E+07 5.40E+07 - - - 2.8638 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.12795.12795.2 0.0267 20-Oct K.LIADVAPSAIR[166.11].E "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1134.6636 1.53 37972 12795 2 1134.665042 568.3391 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 5.84 2888.7 - 156086 - - - 1.2453 - 1.631 0.253 - 283.4 1 2 0 0.0014 11 0 0 0 2.45E+07 1.60E+07 - - - 2.2326 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.12798.12798.2 2.26E-05 18-Nov R.LVNHFVEEFK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1260.6503 20.47 37973 12798 2 1260.654577 631.3324 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2889.1 - 1.37E+06 - - - 3.4141 - 1.884 0.483 - 235.8 1 2 0 0.0043 10 0 0 0 2.61E+07 1.27E+06 - - - 4.3751 0.998 230117_WJC_METTL3_WT_vs_EV_F05.12801.12801.2 0.0834 20-Oct K.LIADVAPSAIR.E "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1124.6554 1.53 37976 12801 2 1124.659783 563.335 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 5.84 2889.5 - 369469 - - - 3.9336 - 1.93 0.291 - 282.9 1 2 0 0.0044 11 0 0 0 2.45E+07 1.60E+07 - - - 2.9677 0.9612 230117_WJC_METTL3_WT_vs_EV_F05.12806.12806.2 0.847 12-May R.VFLQQLK.G "sp|Q13487|SNPC2_HUMAN,tr|M0QXY9|M0QXY9_HUMAN" 2 874.5276 0.03 37979 12806 2 874.529616 438.2711 snRNA-activating protein complex subunit 2 OS=Homo sapiens OX=9606 GN=SNAPC2 PE=1 SV=1 8.72 2890.1 - 328607 - - - 2.2606 - 1.049 0.123 - 54.8 8 2 0 0.002 7 0 0 0 8.82E+06 2.76E+08 - - - -0.303 0.9895 230117_WJC_METTL3_WT_vs_EV_F05.12807.12807.2 0.204 12-Sep K.TELLGLK.E sp|Q69YU5|BWNIN_HUMAN 1 772.4695 1.54 37980 12807 2 772.473062 387.242 Protein BRAWNIN OS=Homo sapiens OX=9606 GN=BRAWNIN PE=1 SV=2 5.66 2890.2 - 1.27E+06 - - - 4.6694 - 1.593 0.169 - 362.6 1 2 0 0.0036 7 0 0 0 4.00E+07 2.60E+07 - - - 1.7634 0.9944 230117_WJC_METTL3_WT_vs_EV_F05.12813.12813.2 0.282 14-Sep K.LISGWVSR[166.11].S "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 926.5213 2.37 37983 12813 2 926.524108 464.2679 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 9.75 2891 - 437776 - - - 3.008 - 1.271 0.216 - 159.6 1 2 0 0.0028 8 0 0 0 8.29E+07 3.49E+07 - - - 1.3587 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.12820.12820.2 0.0124 16-Aug K.AFADPEVLR.R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1016.5291 2.25 37988 12820 2 1016.532781 509.2718 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2891.8 - 437390 - - - 3.6261 - 1.396 0.312 - 221.8 1 2 0 0.0037 9 0 0 0 7.60E+07 3.38E+07 - - - 2.3094 0.8951 230117_WJC_METTL3_WT_vs_EV_F05.12824.12824.2 2.91 14-May R.LVEEELLK[136.11].M sp|Q9BW71|HIRP3_HUMAN 1 979.5681 2.79 37992 12824 2 979.569061 490.7913 HIRA-interacting protein 3 OS=Homo sapiens OX=9606 GN=HIRIP3 PE=1 SV=3 4.25 2892.2 - 853003 - - - 0.9678 - 1 0.04 - 49.7 8 2 0 0.0009 8 0 0 0 2.71E+07 9.69E+06 - - - -1.0673 0.993 230117_WJC_METTL3_WT_vs_EV_F05.12828.12828.2 0.82 12-May R.TILMMGR.Y sp|P13639|EF2_HUMAN 1 820.4299 1.63 37994 12828 2 820.432487 411.2222 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 9.41 2892.6 - 5.60E+06 - - - 3.1349 - 1.216 0.214 - 105.4 1 2 0 0.0026 7 0 0 0 1.51E+08 9.25E+07 - - - 1.2405 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.12831.12831.2 0.00103 14-Sep K.FQNALLVR.Y "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 959.5553 1763.64 37997 12831 2 959.557839 480.7849 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 9.75 2893 - 664952 - - - 2.6981 - 1.797 0.305 - 253.6 1 2 0 0.0026 8 0 0 0 1.18E+08 6.69E+04 - - - 3.0606 0.992 230117_WJC_METTL3_WT_vs_EV_F05.12832.12832.2 0.654 16-Oct K.AIPLALEGK.D "sp|Q9NY93|DDX56_HUMAN,tr|F8WDT8|F8WDT8_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|F8WEI3|F8WEI3_HUMAN" 4 910.5488 1.17 37998 12832 2 910.551896 456.2817 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 6.05 2893.1 - 453657 - - - 3.4353 - 1.663 0.105 - 310.3 1 2 0 0.0031 9 0 0 0 2.52E+07 2.15E+07 - - - 1.287 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.12840.12840.2 2.33E-05 26-Oct R.LVPGGGATEIELAK.Q sp|P50990|TCPQ_HUMAN 1 1353.7504 31.07 38002 12840 2 1353.753931 677.8825 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 2894 - 166959 - - - 2.6223 - 1.997 0.48 - 154.6 1 2 0 0.0036 14 0 0 0 3.46E+07 1.11E+06 - - - 4.3208 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.12843.12843.2 0.682 14-Aug R.GLGATLLR[166.11].D "sp|Q9H1K4|GHC2_HUMAN,sp|Q9H936|GHC1_HUMAN,tr|A0A0D9SFE1|A0A0D9SFE1_HUMAN,tr|A0A0D9SEI9|A0A0D9SEI9_HUMAN,tr|E9PJH7|E9PJH7_HUMAN,tr|E9PS95|E9PS95_HUMAN" 6 809.4999 12.34 38004 12843 2 809.502321 405.7572 Mitochondrial glutamate carrier 2 OS=Homo sapiens OX=9606 GN=SLC25A18 PE=1 SV=1 9.75 2894.4 - 500308 - - - 3.0426 - 1.564 0.212 - 173.4 1 2 0 0.0025 8 0 0 0 1.64E+08 1.33E+07 - - - 1.9549 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.12844.12844.2 0.0225 18-Oct R.LGPSVVGLAR[166.11].Y "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 977.5897 1.41 38005 12844 2 977.591877 489.8021 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 9.75 2894.5 - 1.21E+06 - - - 2.1911 - 1.926 0.3 - 229.4 1 2 0 0.0021 10 0 0 0 7.59E+07 5.40E+07 - - - 3.0857 0.9941 230117_WJC_METTL3_WT_vs_EV_F05.12845.12845.2 0.738 14-Jul R.ILLVGEPR.V "sp|Q8IXI2|MIRO1_HUMAN,tr|J3KSR5|J3KSR5_HUMAN" 2 895.5491 1.57 38006 12845 2 895.551329 448.7818 Mitochondrial Rho GTPase 1 OS=Homo sapiens OX=9606 GN=RHOT1 PE=1 SV=2 6 2894.6 - 412551 - - - 2.4867 - 1.515 0.107 - 165.1 1 2 0 0.0022 8 0 0 0 1.94E+07 1.23E+07 - - - 1.0835 0.8581 230117_WJC_METTL3_WT_vs_EV_F05.12846.12846.2 4.64 12-Apr R.FPPYYMR[166.11].R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 982.461 0.75 38007 12846 2 982.462941 492.2378 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 2894.7 - 163350 - - - 1.9461 - 0.77 0.092 - 48.2 2 2 0 0.0019 7 0 0 0 1.96E+07 2.62E+07 - - - -1.2427 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.12853.12853.2 0.000112 16-Aug K.AFADPEVLR[166.11].R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1026.5374 2.23 38012 12853 2 1026.540383 514.276 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2895.7 - 670926 - - - 2.94 - 1.537 0.435 - 233.4 1 2 0 0.003 9 0 0 0 7.55E+07 3.39E+07 - - - 3.4965 0.9287 230117_WJC_METTL3_WT_vs_EV_F05.12855.12855.2 0.762 12-Jun R.LLEIVER.Q sp|Q12792|TWF1_HUMAN 1 870.5175 1.25 38014 12855 2 870.523073 436.266 Twinfilin-1 OS=Homo sapiens OX=9606 GN=TWF1 PE=1 SV=3 4.53 2896 - 294985 - - - 6.4387 - 1.468 0.117 - 100.2 1 2 0 0.0056 7 0 0 0 5.37E+07 4.31E+07 - - - 1.1198 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.12860.12860.2 0.0779 16-Jun R.LVPLVNGVR.E "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 965.6022 3.13 38016 12860 2 965.604371 483.8084 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 9.75 2896.6 - 2.06E+06 - - - 2.2473 - 1.403 0.231 - 127.6 1 2 0 0.0022 9 0 0 0 1.59E+08 5.08E+07 - - - 1.7261 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.12869.12869.2 0.165 18-Jun R.LGLMPPPEPK.V sp|O43395|PRPF3_HUMAN 1 1077.5893 3.35 38020 12869 2 1077.59049 539.8019 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6 2897.6 - 238159 - - - 1.1479 - 1.198 0.205 - 96.6 1 2 0 0.0012 10 0 0 0 1.28E+07 3.81E+06 - - - 1.059 0.9751 230117_WJC_METTL3_WT_vs_EV_F05.12872.12872.2 1.73 14-Aug K.LLGGLAVR.R "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|H0YF32|H0YF32_HUMAN" 5 797.5123 1.7 38021 12872 2 797.512314 399.7634 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 9.75 2898 - 9.42E+06 - - - -0.0113 - 1.427 0 - 174 1 2 0 0 8 0 0 0 5.20E+09 3.07E+09 - - - 0.1134 0.999 230117_WJC_METTL3_WT_vs_EV_F05.12884.12884.2 0.0142 14-Aug K.GYGFGMVK.L "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RFL1|E5RFL1_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 6 857.4106 1.21 38025 12884 2 857.410839 429.7126 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 8.59 2899.8 - 904771 - - - 0.3254 - 1.19 0.42 - 144.3 1 2 0 0.0003 8 0 0 0 2.61E+07 2.16E+07 - - - 2.6677 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.12892.12892.3 2.40E-05 Nov-44 K.YYVTIIDAPGHR.D "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1403.7197 3.08 38029 12892 3 1403.71406 468.9139 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.74 2900.8 - 371716 - - - -4.0535 - 2.035 0.46 - 66.1 1 2 0 -0.0057 12 0 0 0 2.55E+07 8.26E+06 - - - 5.6364 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.12895.12895.2 0.22 12-Aug R.VAIFIEK.T sp|Q9P258|RCC2_HUMAN 1 818.4902 1.66 38030 12895 2 818.489937 410.2524 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2901.2 - 1.27E+06 - - - -0.3103 - 1.393 0.232 - 206.9 1 2 0 -0.0003 7 0 0 0 8.68E+07 5.24E+07 - - - 1.8047 0.89 230117_WJC_METTL3_WT_vs_EV_F05.12896.12896.2 5.99 12-Aug K.TVYSILR[166.11].H "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 860.4995 0.65 38031 12896 2 860.497895 431.257 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 8.41 2901.3 - 819772 - - - -1.8919 - 1.058 0.086 - 231.5 1 2 0 -0.0016 7 0 0 0 1.83E+08 2.79E+08 - - - -0.1457 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.12899.12899.2 0.493 12-Jul R.VAIFIEK[136.11].T sp|Q9P258|RCC2_HUMAN 1 826.5044 1.68 38032 12899 2 826.503911 414.2595 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2901.7 - 957582 - - - -0.5808 - 1.892 0.139 - 185.3 1 2 0 -0.0005 7 0 0 0 8.68E+07 5.18E+07 - - - 2.0879 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.12902.12902.2 0.163 16-Jul K.MLVVGGIDR.V sp|Q15046|SYK_HUMAN 1 958.527 1.15 38033 12902 2 958.526576 480.2708 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2902.1 - 2.74E+06 - - - -0.4288 - 1.496 0.201 - 222.7 1 2 0 -0.0004 9 0 0 0 1.66E+08 1.45E+08 - - - 1.6908 0.995 230117_WJC_METTL3_WT_vs_EV_F05.12904.12904.2 1.37 12-Jun K.ELVTLYR.R sp|Q8TD55|PKHO2_HUMAN 1 892.5018 1.31 38034 12904 2 892.504179 447.2582 Pleckstrin homology domain-containing family O member 2 OS=Homo sapiens OX=9606 GN=PLEKHO2 PE=1 SV=1 6.1 2902.3 - 797789 - - - 2.6454 - 1.34 0.178 - 155.3 1 2 0 0.0024 7 0 0 0 3.48E+07 2.66E+07 - - - 1.2823 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.12909.12909.2 0.0186 16-Aug K.MLVVGGIDR[166.11].V sp|Q15046|SYK_HUMAN 1 968.5353 1.15 38036 12909 2 968.535589 485.2749 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2902.9 - 3.12E+06 - - - 0.3428 - 1.792 0.387 - 284.6 1 2 0 0.0003 9 0 0 0 1.65E+08 1.45E+08 - - - 3.5869 0.976 230117_WJC_METTL3_WT_vs_EV_F05.12915.12915.2 0.247 14-Jul R.SPAQILLR[166.11].W "sp|P14550|AK1A1_HUMAN,sp|Q96JD6|AKCL2_HUMAN,tr|G3V1C1|G3V1C1_HUMAN" 3 906.5526 3.18 38038 12915 2 906.55146 454.2836 Aldo-keto reductase family 1 member A1 OS=Homo sapiens OX=9606 GN=AKR1A1 PE=1 SV=3 9.47 2903.7 - 661853 - - - -1.2807 - 1.117 0.176 - 87.1 1 2 0 -0.0012 8 0 0 0 7.24E+07 2.28E+07 - - - 0.6743 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.12916.12916.2 0.544 12-Jul K.ILEVDLK[136.11].N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 836.5099 0.91 38039 12916 2 836.510009 419.2622 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2903.9 - 977253 - - - 0.1662 - 1.583 0.115 - 129.3 1 2 0 0.0001 7 0 0 0 1.50E+08 1.66E+08 - - - 1.3457 0.9953 230117_WJC_METTL3_WT_vs_EV_F05.12929.12929.2 0.0419 12-May R.QVAIVFR.T "sp|Q04206|TF65_HUMAN,tr|A0A087X0W8|A0A087X0W8_HUMAN,tr|E9PKH5|E9PKH5_HUMAN,tr|Q2TAM5|Q2TAM5_HUMAN" 4 831.4967 3.63 38041 12929 2 831.496594 416.7556 Transcription factor p65 OS=Homo sapiens OX=9606 GN=RELA PE=1 SV=2 9.75 2906 - 2.16E+06 - - - -0.095 - 1.283 0.226 - 83.7 2 2 0 -0.0001 7 0 0 0 9.02E+07 2.48E+07 - - - 1.3653 0.9826 230117_WJC_METTL3_WT_vs_EV_F05.12943.12943.2 0.39 12-Jun K.FEPTVFR.D "sp|Q9Y6E2|BZW2_HUMAN,tr|F8WDX8|F8WDX8_HUMAN,tr|E7EMS9|E7EMS9_HUMAN,tr|E9PFE3|E9PFE3_HUMAN,tr|E7ETZ4|E7ETZ4_HUMAN,tr|C9JF98|C9JF98_HUMAN,tr|Q75MG1|Q75MG1_HUMAN" 7 894.46 0.68 38047 12943 2 894.458925 448.2373 Basic leucine zipper and W2 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=BZW2 PE=1 SV=1 6 2907.8 - 382095 - - - -1.1493 - 1.161 0.181 - 99.3 1 2 0 -0.001 7 0 0 0 1.45E+07 2.12E+07 - - - 0.8506 0.9795 230117_WJC_METTL3_WT_vs_EV_F05.12944.12944.2 1.19 14-Jun K.FIINSYPK.Y "sp|Q96EY7|PTCD3_HUMAN,tr|B8ZZQ4|B8ZZQ4_HUMAN" 2 980.5331 1 38048 12944 2 980.533154 491.2738 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 8.59 2907.9 - 635215 - - - 0.0367 - 1.095 0.142 - 94.6 2 2 0 0 8 0 0 0 1.46E+07 1.46E+07 - - - 0.229 0.9853 230117_WJC_METTL3_WT_vs_EV_F05.12953.12953.2 1.15 14-Jun K.FIINSYPK[136.11].Y "sp|Q96EY7|PTCD3_HUMAN,tr|B8ZZQ4|B8ZZQ4_HUMAN" 2 988.5473 0.99 38051 12953 2 988.547576 495.2809 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 8.59 2909.1 - 288241 - - - 0.261 - 1.194 0.109 - 64.4 1 2 0 0.0003 8 0 0 0 1.47E+07 1.49E+07 - - - 0.3807 0.991 230117_WJC_METTL3_WT_vs_EV_F05.12966.12966.2 0.202 12-Jul K.LSSLFVK.C sp|Q92616|GCN1_HUMAN 1 792.4745 0.82 38056 12966 2 792.474348 397.2445 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.75 2910.8 - 814267 - - - -0.2435 - 1.408 0.108 - 109.8 1 2 0 -0.0002 7 0 0 0 5.20E+07 6.38E+07 - - - 0.9228 0.8941 230117_WJC_METTL3_WT_vs_EV_F05.12972.12972.2 8.09 12-Jul R.AFGIPVR[166.11].C sp|Q00535|CDK5_HUMAN 1 768.4522 1.22 38060 12972 2 768.452101 385.2334 Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3 9.79 2911.6 - 889289 - - - -0.1015 - 1.05 0.016 - 150.2 2 2 0 -0.0001 7 0 0 0 9.21E+07 7.58E+07 - - - -0.8207 0.998 230117_WJC_METTL3_WT_vs_EV_F05.12978.12978.2 2.14 14-Aug R.QMAAVLLR[166.11].R "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 11 910.5298 1.19 38064 12978 2 910.530405 456.2722 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 2912.3 - 729959 - - - 0.6886 - 1.742 0.145 - 194.9 1 2 0 0.0006 8 0 0 0 6.40E+07 5.37E+07 - - - 1.7857 0.9928 230117_WJC_METTL3_WT_vs_EV_F05.12987.12987.2 0.0214 14-Jul K.LTPVLLAK[136.11].Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 861.5779 1.8 38069 12987 2 861.57775 431.7962 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2913.4 - 3.97E+06 - - - -0.1625 - 1.207 0.196 - 145.6 1 2 0 -0.0001 8 0 0 0 3.42E+08 1.90E+08 - - - 1.056 0.982 230117_WJC_METTL3_WT_vs_EV_F05.12988.12988.3 0.774 Nov-44 R.LIDLHSPSEIVK[136.11].Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1357.7697 2.13 38070 12988 3 1357.770497 453.5972 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2913.5 - 462292 - - - 0.6113 - 1.666 0.108 - 111.7 1 2 0 0.0008 12 0 0 0 4.27E+07 2.01E+07 - - - 1.1587 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.12989.12989.2 0.00864 14-Sep K.VVLVLAGR[166.11].Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 835.5519 0.77 38071 12989 2 835.553977 418.7832 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2913.6 - 2.53E+06 - - - 2.4942 - 1.758 0.322 - 274.7 1 2 0 0.0021 8 0 0 0 2.00E+09 2.59E+09 - - - 3.1202 0.978 230117_WJC_METTL3_WT_vs_EV_F05.12990.12990.2 0.137 12-Jun K.VVIDAFR[166.11].L sp|O00487|PSDE_HUMAN 1 828.4733 1.79 38072 12990 2 828.474622 415.2439 26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1 5.81 2913.6 - 1.59E+06 - - - 1.586 - 1.28 0.035 - 106.7 2 2 0 0.0013 7 0 0 0 3.77E+08 2.10E+08 - - - -0.0532 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.12994.12994.2 0.00209 14-Sep K.VVLVLAGR.Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 825.5436 0.77 38074 12994 2 825.545242 413.7791 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2914.2 - 2.09E+06 - - - 1.9611 - 1.751 0.418 - 390.5 1 2 0 0.0016 8 0 0 0 2.00E+09 2.59E+09 - - - 3.8173 0.8527 230117_WJC_METTL3_WT_vs_EV_F05.12995.12995.2 0.609 12-Jul A.AILPC[160.03]LK.E "sp|Q9P2H5|UBP35_HUMAN,sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT04|J3KT04_HUMAN,tr|J3KS93|J3KS93_HUMAN,tr|E7EMV8|E7EMV8_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|H0YEP1|H0YEP1_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|F8WE11|F8WE11_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|E9PBH4|E9PBH4_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QQP0|J3QQP0_HUMAN,tr|J3QR64|J3QR64_HUMAN,tr|J3KSN7|J3KSN7_HUMAN" 20 813.4782 2.52 38075 12995 2 813.479347 407.7464 Ubiquitin carboxyl-terminal hydrolase 35 OS=Homo sapiens OX=9606 GN=USP35 PE=1 SV=3 8.27 2914.3 - 320538 - - - 1.3534 - 1.458 0.191 - 136 1 1 0 0.0011 7 0 0 0 6.99E+07 2.77E+07 - - - 1.6461 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.13009.13009.2 0.0751 12-Aug R.FASFIER[166.11].V sp|P07196|NFL_HUMAN 1 878.4526 1.77 38082 13009 2 878.455412 440.2336 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2916.1 - 1.54E+06 - - - 3.2318 - 1.575 0.223 - 206.2 1 2 0 0.0028 7 0 0 0 1.09E+08 6.15E+07 - - - 2.1265 0.9963 230117_WJC_METTL3_WT_vs_EV_F05.13021.13021.2 0.305 14-Jun K.LTPVLLAK.Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 853.5637 1.8 38088 13021 2 853.565117 427.7891 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2917.6 - 7.71E+06 - - - 1.6718 - 1.106 0.255 - 98.4 1 2 0 0.0014 8 0 0 0 3.42E+08 1.90E+08 - - - 1.2278 0.999 230117_WJC_METTL3_WT_vs_EV_F05.13024.13024.2 0.00602 14-Jul R.IFNTFGPR[166.11].M "sp|Q8NBZ7|UXS1_HUMAN,tr|C9JCB7|C9JCB7_HUMAN,tr|C9JFU6|C9JFU6_HUMAN,tr|C9JE50|C9JE50_HUMAN" 4 960.5057 0.82 38089 13024 2 960.507596 481.2601 UDP-glucuronic acid decarboxylase 1 OS=Homo sapiens OX=9606 GN=UXS1 PE=1 SV=1 9.75 2918 - 217239 - - - 2.0042 - 1.458 0.316 - 94.8 1 2 0 0.0019 8 0 0 0 3.58E+07 4.35E+07 - - - 2.5116 0.9704 230117_WJC_METTL3_WT_vs_EV_F05.13031.13031.2 4.25 12-Jun K.LLSITVR[166.11].N "sp|P78527|PRKDC_HUMAN,tr|B1APQ0|B1APQ0_HUMAN" 2 810.5203 1.38 38093 13031 2 810.522343 406.2674 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 2918.9 - 663860 - - - 2.5712 - 1.41 0.008 - 85.4 3 2 0 0.0021 7 0 0 0 2.98E+07 2.16E+07 - - - -0.025 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.13032.13032.2 0.0496 12-Jun K.ILMEFNK.M sp|Q9UQE7|SMC3_HUMAN 1 893.4681 1.55 38094 13032 2 893.470308 447.7413 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2919 - 436820 - - - 2.4992 - 1.263 0.384 - 82.7 1 2 0 0.0022 7 0 0 0 6.43E+07 4.15E+07 - - - 2.6163 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.13036.13036.2 0.125 12-Aug R.FASFIER.V sp|P07196|NFL_HUMAN 1 868.4443 1.83 38095 13036 2 868.446092 435.2294 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2919.6 - 2.74E+06 - - - 2.06 - 1.663 0.202 - 197.3 1 2 0 0.0018 7 0 0 0 1.12E+08 6.15E+07 - - - 2.144 0.999 230117_WJC_METTL3_WT_vs_EV_F05.13047.13047.2 0.881 14-Sep K.IADFGLAR.L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 861.4709 2.87 38101 13047 2 861.471533 431.7427 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2921 - 2.95E+06 - - - 0.7905 - 1.769 0.23 - 214.1 1 2 0 0.0007 8 0 0 0 1.23E+08 4.28E+07 - - - 2.4599 0.9919 230117_WJC_METTL3_WT_vs_EV_F05.13048.13048.2 4.93 12-Jun R.LISSLLR.T "sp|Q9BQ52|RNZ2_HUMAN,sp|Q8NCN5|PDPR_HUMAN,sp|Q96P20|NLRP3_HUMAN,sp|Q96MN2|NALP4_HUMAN,sp|Q8NGV5|O13D1_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|A0A7I2PMC6|A0A7I2PMC6_HUMAN,tr|E7ES68|E7ES68_HUMAN,tr|A0A2R8YEG7|A0A2R8YEG7_HUMAN,tr|A8MT40|A8MT40_HUMAN,tr|A0A7I2PJH0|A0A7I2PJH0_HUMAN,tr|H3BQG3|H3BQG3_HUMAN,tr|A0A7I2PRX0|A0A7I2PRX0_HUMAN,tr|A0A7I2YME5|A0A7I2YME5_HUMAN,tr|A0A286YF94|A0A286YF94_HUMAN,tr|A0A7I2UNQ2|A0A7I2UNQ2_HUMAN,tr|A0A7I2R3P8|A0A7I2R3P8_HUMAN" 17 800.512 1.4 38102 13048 2 800.514047 401.2633 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 9.75 2921.1 - 1.06E+06 - - - 2.5709 - 1.445 0.091 - 107.8 1 2 0 0.0021 7 0 0 0 3.01E+07 2.15E+07 - - - 0.8789 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.13049.13049.2 0.115 14-Jul K.LLAEVTLK.T "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 4 885.5535 2.52 38103 13049 2 885.554514 443.784 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 6 2921.2 - 1.56E+06 - - - 1.1236 - 1.401 0.294 - 120 1 2 0 0.001 8 0 0 0 1.39E+08 5.53E+07 - - - 2.2291 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.13057.13057.2 0.587 14-Jun R.LFAAELGR.E "sp|O00255|MEN1_HUMAN,tr|A0A5F9ZHS3|A0A5F9ZHS3_HUMAN,tr|E7EN32|E7EN32_HUMAN,tr|Q9GZQ5|Q9GZQ5_HUMAN,tr|E7ENS2|E7ENS2_HUMAN" 5 875.4865 1.4 38105 13057 2 875.488206 438.7505 Menin OS=Homo sapiens OX=9606 GN=MEN1 PE=1 SV=4 6 2922.3 - 1.11E+06 - - - 1.9463 - 1.318 0.197 - 66.8 3 2 0 0.0017 8 0 0 0 4.28E+07 3.05E+07 - - - 1.1151 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.13062.13062.2 0.23 12-Jul K.ILMEFNK[136.11].M sp|Q9UQE7|SMC3_HUMAN 1 901.4823 1.52 38108 13062 2 901.483738 451.7484 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2923 - 603744 - - - 1.6229 - 1.324 0.265 - 112.1 1 2 0 0.0015 7 0 0 0 6.59E+07 4.34E+07 - - - 1.8871 0.995 230117_WJC_METTL3_WT_vs_EV_F05.13063.13063.2 1.76 14-Jun K.LLAEVTLK[136.11].T "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 4 893.5677 2.52 38109 13063 2 893.56886 447.7911 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 6 2923 - 1.26E+06 - - - 1.2769 - 1.085 0.229 - 57.6 1 2 0 0.0011 8 0 0 0 1.40E+08 5.54E+07 - - - 0.9781 0.999 230117_WJC_METTL3_WT_vs_EV_F05.13066.13066.2 0.18 12-Aug K.VVIDAFR.L sp|O00487|PSDE_HUMAN 1 818.465 1.81 38110 13066 2 818.466491 410.2398 26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1 5.81 2923.4 - 3.88E+06 - - - 1.7753 - 1.672 0.242 - 322.8 1 2 0 0.0015 7 0 0 0 3.80E+08 2.10E+08 - - - 2.4567 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.13073.13073.2 0.00298 20-Jul K.YGQISEVVVVK[136.11].D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1227.6954 1 38112 13073 2 1227.697476 614.855 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2924.4 - 167919 - - - 1.6592 - 1.336 0.363 - 144.3 1 2 0 0.002 11 0 0 0 5.00E+06 5.01E+06 - - - 2.5051 0.9957 230117_WJC_METTL3_WT_vs_EV_F05.13081.13081.2 0.0554 14-Jul K.IGDFGLAR.D "sp|P08922|ROS1_HUMAN,sp|P07333|CSF1R_HUMAN,sp|P51617|IRAK1_HUMAN,sp|Q96PY6|NEK1_HUMAN,sp|P51955|NEK2_HUMAN,sp|Q6P3R8|NEK5_HUMAN,sp|Q16659|MK06_HUMAN,sp|P31152|MK04_HUMAN,tr|E9PIX7|E9PIX7_HUMAN,tr|H7C2I6|H7C2I6_HUMAN,tr|K7EN18|K7EN18_HUMAN,tr|A0A494C168|A0A494C168_HUMAN,tr|F6U4U2|F6U4U2_HUMAN,tr|H7C224|H7C224_HUMAN,tr|K7ELV1|K7ELV1_HUMAN,tr|Q5H8Y1|Q5H8Y1_HUMAN,tr|A0A3B3ITQ6|A0A3B3ITQ6_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 18 847.4552 2.29 38116 13081 2 847.455309 424.7349 Proto-oncogene tyrosine-protein kinase ROS OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3 5.84 2925.4 - 1.98E+06 - - - 0.1263 - 1.821 0.066 - 127.7 1 2 0 0.0001 8 0 0 0 7.61E+07 3.33E+07 - - - 1.3362 0.9935 230117_WJC_METTL3_WT_vs_EV_F05.13082.13082.2 4.36 12-Jul R.LALEELR.S sp|Q99496|RING2_HUMAN 1 842.4862 1.19 38117 13082 2 842.486608 422.2504 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.53 2925.5 - 725688 - - - 0.5223 - 1.395 0.108 - 136.8 1 2 0 0.0004 7 0 0 0 2.51E+08 2.11E+08 - - - 0.8933 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.13089.13089.2 0.283 14-Aug K.LALDYGIK[136.11].F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 899.5208 1.16 38122 13089 2 899.523286 450.7677 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 2926.3 - 828568 - - - 2.7982 - 1.719 0.223 - 152.5 1 2 0 0.0025 8 0 0 0 2.40E+07 2.06E+07 - - - 2.3212 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.13109.13109.2 0.448 14-May K.VLPITVPK.S sp|Q9ULW0|TPX2_HUMAN 1 865.5637 2.09 38133 13109 2 865.564738 433.7891 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.72 2928.8 - 496432 - - - 1.2108 - 1.066 0.308 - 55.1 1 2 0 0.001 8 0 0 0 5.23E+07 2.51E+07 - - - 1.5083 0.9111 230117_WJC_METTL3_WT_vs_EV_F05.13112.13112.2 0.274 14-Jun K.LLVLDATK.R "sp|O15530|PDPK1_HUMAN,sp|Q6A1A2|PDPK2_HUMAN,tr|E9PER6|E9PER6_HUMAN" 3 871.5379 2.7 38135 13112 2 871.537355 436.7762 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1 5.84 2929.1 - 436255 - - - -0.5898 - 1.033 0.046 - 71.9 1 2 0 -0.0005 8 0 0 0 1.10E+07 4.08E+06 - - - -0.5215 0.9969 230117_WJC_METTL3_WT_vs_EV_F05.13116.13116.2 0.0299 20-Aug K.YGQISEVVVVK.D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1219.6812 1 38139 13116 2 1219.681339 610.8479 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2929.6 - 176540 - - - 0.082 - 1.12 0.31 - 79.3 1 2 0 0.0001 11 0 0 0 5.00E+06 5.01E+06 - - - 1.6372 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.13125.13125.2 0.254 16-Aug R.ILVLNGGYR.G "sp|O60870|KIN17_HUMAN,tr|S4R357|S4R357_HUMAN" 2 1003.5815 1.73 38145 13125 2 1003.582649 502.798 DNA\RNA-binding protein KIN17 OS=Homo sapiens OX=9606 GN=KIN PE=1 SV=2 8.75 2930.6 - 981082 - - - 1.1798 - 1.609 0.327 - 201 1 2 0 0.0012 9 0 0 0 1.82E+07 1.05E+07 - - - 2.8318 0.9556 230117_WJC_METTL3_WT_vs_EV_F05.13130.13130.2 0.00433 14-Aug E.ILNPLVSK.A "sp|Q6NUP7|PP4R4_HUMAN,sp|Q9BSC4|NOL10_HUMAN,tr|G3V431|G3V431_HUMAN" 3 882.5539 1.07 38148 13130 2 882.554128 442.2842 Serine\threonine-protein phosphatase 4 regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PPP4R4 PE=1 SV=1 8.75 2931.3 - 2.37E+06 - - - 0.3105 - 1.443 0.432 - 144.6 1 1 0 0.0003 8 0 0 0 8.33E+07 7.82E+07 - - - 3.3377 0.9569 230117_WJC_METTL3_WT_vs_EV_F05.13131.13131.2 1.71 16-Jun K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 10.21 38149 13131 2 1014.537727 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 2931.4 - 741814 - - - 3.1068 - 1.195 0.079 - 61.8 3 2 0 0.0032 9 0 0 0 1.61E+07 1.57E+06 - - - -0.0742 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.13135.13135.2 0.00225 16-Jul R.EQVNDLFSR.K "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1106.5356 0.49 38153 13135 2 1106.536591 554.2751 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 2931.9 - 218541 - - - 0.8622 - 1.46 0.343 - 141.1 1 2 0 0.001 9 0 0 0 4.00E+06 8.14E+06 - - - 2.6689 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.13140.13140.2 0.000297 14-Aug K.VVNPLFEK.R "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 944.5331 0.79 38156 13140 2 944.534137 473.2738 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.97 2932.6 - 456549 - - - 1.0788 - 1.503 0.403 - 201.3 1 2 0 0.001 8 0 0 0 8.44E+07 1.07E+08 - - - 3.2461 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.13144.13144.2 0.122 14-Aug K.VVNPLFEK[136.11].R "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 952.5473 0.83 38158 13144 2 952.547997 477.2809 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.97 2933.1 - 1.27E+06 - - - 0.7128 - 1.545 0.276 - 170.4 1 2 0 0.0007 8 0 0 0 8.96E+07 1.08E+08 - - - 2.3913 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.13146.13146.2 0.101 14-Aug K.INELLLAK[136.11].E "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 920.5786 2.45 38160 13146 2 920.581161 461.2966 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 6 2933.3 - 741434 - - - 2.7624 - 1.271 0.266 - 126.5 1 2 0 0.0025 8 0 0 0 4.94E+07 2.02E+07 - - - 1.7281 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.13147.13147.2 0.142 14-Jul K.VLTISTLR.L "sp|Q12830|BPTF_HUMAN,tr|F5GXF5|F5GXF5_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN,tr|A0A0A0MR81|A0A0A0MR81_HUMAN" 6 901.5597 0.62 38161 13147 2 901.561415 451.7871 Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3 9.72 2933.4 - 670092 - - - 1.9389 - 1.283 0.24 - 131.6 1 2 0 0.0017 8 0 0 0 1.29E+07 2.09E+07 - - - 1.5647 0.9232 230117_WJC_METTL3_WT_vs_EV_F05.13163.13163.2 0.818 14-Sep S.LAELTGIK[136.11].W "sp|Q71F56|MD13L_HUMAN,tr|A0A3B3IS36|A0A3B3IS36_HUMAN,tr|A0A3B3IRX3|A0A3B3IRX3_HUMAN" 3 851.5208 0.55 38170 13163 2 851.52161 426.7677 Mediator of RNA polymerase II transcription subunit 13-like OS=Homo sapiens OX=9606 GN=MED13L PE=1 SV=1 6 2935.4 - 5.48E+06 - - - 0.9876 - 1.694 0.235 - 264.7 1 1 0 0.0008 8 0 0 0 8.88E+07 1.61E+08 - - - 2.3661 0.9949 230117_WJC_METTL3_WT_vs_EV_F05.13167.13167.2 1.34 16-Jun K.LLSGNLALR[166.11].S sp|Q53S58|TM177_HUMAN 1 965.5897 0.78 38174 13167 2 965.590917 483.8021 Transmembrane protein 177 OS=Homo sapiens OX=9606 GN=TMEM177 PE=1 SV=1 9.75 2935.9 - 464755 - - - 1.2241 - 1.383 0.169 - 79 4 2 0 0.0012 9 0 0 0 5.77E+06 7.35E+06 - - - 0.958 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.13171.13171.2 0.215 14-Jun R.LFVGSIPK.S "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 859.5167 0.91 38176 13171 2 859.517993 430.7656 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.75 2936.3 - 2.83E+06 - - - 1.4578 - 1.208 0.202 - 117.6 1 2 0 0.0013 8 0 0 0 1.27E+09 1.40E+09 - - - 1.1025 0.9601 230117_WJC_METTL3_WT_vs_EV_F05.13182.13182.2 1.18 12-Jun K.TIADIIR.T "sp|P49368|TCPG_HUMAN,sp|Q16878|CDO1_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 800.4756 9.89 38183 13182 2 800.477134 401.2451 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.5 2937.7 - 2.66E+06 - - - 1.9126 - 1.187 0.002 - 142.1 1 2 0 0.0015 7 0 0 0 1.87E+09 1.89E+08 - - - -0.4015 0.9514 230117_WJC_METTL3_WT_vs_EV_F05.13183.13183.2 6.05 12-May K.FIPLYSK[136.11].V "sp|Q14694|UBP10_HUMAN,tr|J3KT19|J3KT19_HUMAN,tr|H3BVF1|H3BVF1_HUMAN" 3 874.5044 1.2 38184 13183 2 874.505162 438.2595 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.59 2937.8 - 445319 - - - 0.8816 - 0.949 0.078 - 62.5 1 2 0 0.0008 7 0 0 0 9.94E+07 8.28E+07 - - - -0.549 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.13189.13189.2 5.98E-05 14-Sep -.MFAPAVMR[166.11].A sp|Q9P0S2|COX16_HUMAN 1 931.4647 1.65 38188 13189 2 931.466146 466.7396 "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COX16 PE=1 SV=1" 9.5 2938.5 - 536378 - - - 1.5159 - 1.85 0.223 - 330.5 1 2 0 0.0014 8 0 0 0 3.71E+07 2.25E+07 - - - 2.543 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.13190.13190.2 0.0616 14-Jul R.IFTNLYGR.H "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 4 982.5236 1.14 38189 13190 2 982.525946 492.2691 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.75 2938.6 - 407963 - - - 2.3714 - 1.448 0.319 - 116.8 1 2 0 0.0023 8 0 0 0 5.15E+07 4.51E+07 - - - 2.5129 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.13197.13197.2 0.0114 12-Jul K.YGVDLIR.Y sp|Q6UXN9|WDR82_HUMAN 1 834.46 1.5 38194 13197 2 834.46143 418.2373 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 5.84 2939.5 - 1.90E+06 - - - 1.77 - 1.397 0.189 - 189.4 1 2 0 0.0015 7 0 0 0 7.05E+07 4.68E+07 - - - 1.4958 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.13198.13198.2 1.24E-05 14-Sep -.MFAPAVMR.A sp|Q9P0S2|COX16_HUMAN 1 921.4565 1.65 38195 13198 2 921.457728 461.7355 "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COX16 PE=1 SV=1" 9.5 2939.6 - 1.15E+06 - - - 1.3717 - 1.626 0.244 - 305.5 1 2 0 0.0013 8 0 0 0 3.71E+07 2.25E+07 - - - 2.3089 0.9851 230117_WJC_METTL3_WT_vs_EV_F05.13204.13204.2 0.535 22-Jul R.LLLGPAGGGVPK.L sp|Q96SL8|FIZ1_HUMAN 1 1077.6546 1.32 38199 13204 2 1077.657135 539.8346 Flt3-interacting zinc finger protein 1 OS=Homo sapiens OX=9606 GN=FIZ1 PE=1 SV=2 8.75 2940.4 - 174597 - - - 2.3245 - 1.321 0.079 - 82.4 1 2 0 0.0025 12 0 0 0 8.60E+06 6.51E+06 - - - 0.3562 0.9087 230117_WJC_METTL3_WT_vs_EV_F05.13208.13208.2 1.16 12-Jun R.SVTLLIK.G sp|P40227|TCPZ_HUMAN 1 772.5058 8.27 38201 13208 2 772.506987 387.2602 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 8.47 2940.9 - 1.37E+06 - - - 1.4835 - 1.101 0.015 - 116.3 10 2 0 0.0011 7 0 0 0 3.32E+09 4.02E+08 - - - -0.9904 0.9413 230117_WJC_METTL3_WT_vs_EV_F05.13214.13214.2 6.96 22-Jun R.LLLGPAGGGVPK[136.11].L sp|Q96SL8|FIZ1_HUMAN 1 1085.6688 1.31 38205 13214 2 1085.671261 543.8417 Flt3-interacting zinc finger protein 1 OS=Homo sapiens OX=9606 GN=FIZ1 PE=1 SV=2 8.75 2941.6 - 229822 - - - 2.2392 - 1.066 0.071 - 43.9 5 2 0 0.0024 12 0 0 0 8.60E+06 6.57E+06 - - - -0.5794 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.13219.13219.2 0.191 14-Sep R.LLAAFEER.E "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 947.5076 1.26 38207 13219 2 947.50895 474.7611 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.53 2942.2 - 1.55E+06 - - - 1.391 - 1.755 0.206 - 267.5 1 2 0 0.0013 8 0 0 0 1.42E+08 1.13E+08 - - - 2.2585 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.13221.13221.2 0.0165 12-Jul K.YGVDLIR[166.11].Y sp|Q6UXN9|WDR82_HUMAN 1 844.4682 1.55 38208 13221 2 844.469792 423.2414 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 5.84 2942.5 - 1.79E+06 - - - 1.858 - 1.504 0.33 - 195.7 1 2 0 0.0016 7 0 0 0 7.47E+07 4.81E+07 - - - 2.7711 0.9938 230117_WJC_METTL3_WT_vs_EV_F05.13223.13223.2 4.35 12-Jul K.SVIISIK[136.11].G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 766.5044 1.17 38210 13223 2 766.505534 384.2595 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2942.7 - 855758 - - - 1.4912 - 1.241 0.147 - 189.8 1 2 0 0.0011 7 0 0 0 1.91E+08 1.63E+08 - - - 0.8105 0.9948 230117_WJC_METTL3_WT_vs_EV_F05.13228.13228.2 0.552 12-Jun K.SVIISIK.G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 758.4902 1.17 38213 13228 2 758.491366 380.2524 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2943.3 - 726540 - - - 1.5491 - 1.131 0.206 - 146.4 1 2 0 0.0012 7 0 0 0 1.91E+08 1.63E+08 - - - 0.9522 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.13231.13231.2 0.00143 16-Jul R.EMGVIAAMR.D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 976.4834 2.46 38214 13231 2 976.482385 489.249 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 6.1 2943.7 - 294906 - - - -1.0466 - 1.576 0.368 - 128.6 1 2 0 -0.001 9 0 0 0 1.48E+07 6.04E+06 - - - 3.0747 1 230117_WJC_METTL3_WT_vs_EV_F05.13232.13232.2 2.86E-06 24-Oct R.TTPSYVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1486.694 16.52 38215 13232 2 1486.700563 744.3543 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2943.8 - 150030 - - - 4.4219 - 2.293 0.632 - 257.7 1 2 0 0.0066 13 0 0 0 7.60E+07 4.60E+06 - - - 5.8368 0.9935 230117_WJC_METTL3_WT_vs_EV_F05.13236.13236.2 2.26 14-Aug K.NLILAGVK.G "sp|Q9UBE0|SAE1_HUMAN,tr|B3KNJ4|B3KNJ4_HUMAN,tr|M0QZS6|M0QZS6_HUMAN,tr|A0A590UKC5|A0A590UKC5_HUMAN,tr|M0QX65|M0QX65_HUMAN,tr|A0A590UKA0|A0A590UKA0_HUMAN,tr|A0A590UK93|A0A590UK93_HUMAN" 7 826.5276 3.02 38216 13236 2 826.527931 414.2711 SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1 PE=1 SV=1 8.75 2944.4 - 931608 - - - 0.3533 - 1.647 0.054 - 197.9 1 2 0 0.0003 8 0 0 0 4.81E+07 1.59E+07 - - - 0.9446 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.13239.13239.2 0.0607 12-Sep R.NLPMHLR.R "sp|Q9P2E3|ZNFX1_HUMAN,tr|Q5JXR6|Q5JXR6_HUMAN,tr|Q5JXR7|Q5JXR7_HUMAN,tr|Q5JXR5|Q5JXR5_HUMAN" 4 879.4749 146.88 38218 13239 2 879.47527 440.7447 NFX1-type zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=ZNFX1 PE=2 SV=2 9.76 2944.7 - 1.75E+06 - - - 0.4298 - 1.815 0.323 - 268.9 1 2 0 0.0004 7 0 0 0 1.61E+08 1.10E+06 - - - 3.3153 0.993 230117_WJC_METTL3_WT_vs_EV_F05.13240.13240.2 0.0441 14-May K.LVVWAADR.Q "sp|Q96RQ3|MCCA_HUMAN,tr|G5E9X5|G5E9X5_HUMAN,tr|E9PG35|E9PG35_HUMAN,tr|E9PHF7|E9PHF7_HUMAN,tr|F5GYT8|F5GYT8_HUMAN" 5 928.5131 1.95 38219 13240 2 928.516231 465.2638 "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC1 PE=1 SV=3" 5.84 2944.8 - 579888 - - - 3.4248 - 1.383 0.215 - 58.2 3 2 0 0.0032 8 0 0 0 2.65E+07 1.36E+07 - - - 1.3928 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.13248.13248.2 0.00266 14-Aug R.LLAAFEER[166.11].E "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 957.5159 1.27 38222 13248 2 957.516638 479.7652 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.53 2946 - 2.79E+06 - - - 0.7687 - 1.741 0.384 - 214.2 1 2 0 0.0007 8 0 0 0 1.43E+08 1.13E+08 - - - 3.5492 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.13249.13249.2 0.000527 16-Sep K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 421.02 38223 13249 2 1059.558214 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2946.1 - 331990 - - - 2.0537 - 1.663 0.388 - 273.5 1 2 0 0.0022 9 0 0 0 2.45E+07 5.81E+04 - - - 3.3776 0.9928 230117_WJC_METTL3_WT_vs_EV_F05.13252.13252.2 0.275 12-Jun K.YVIYIER[166.11].V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 964.5257 0.8 38224 13252 2 964.524494 483.2701 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 6 2946.5 - 248957 - - - -1.2898 - 1.371 0.215 - 136.4 1 2 0 -0.0012 7 0 0 0 1.05E+09 1.32E+09 - - - 1.6284 0.998 230117_WJC_METTL3_WT_vs_EV_F05.13258.13258.2 0.177 18-Nov R.LLAEPVPGIK[136.11].A "sp|P61088|UBE2N_HUMAN,sp|Q5JXB2|UE2NL_HUMAN,tr|F8VZ29|F8VZ29_HUMAN,tr|F8VSD4|F8VSD4_HUMAN,tr|F8VV71|F8VV71_HUMAN" 5 1043.647 1.64 38227 13258 2 1043.649041 522.8308 Ubiquitin-conjugating enzyme E2 N OS=Homo sapiens OX=9606 GN=UBE2N PE=1 SV=1 6 2947.2 - 729501 - - - 1.925 - 1.774 0.154 - 315 1 2 0 0.002 10 0 0 0 1.28E+08 7.79E+07 - - - 1.7779 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.13260.13260.2 0.0314 18-Aug R.AFGSLGPGLR.L "sp|Q96JG8|MAGD4_HUMAN,tr|D6RBW3|D6RBW3_HUMAN,tr|A0A804HHZ9|A0A804HHZ9_HUMAN" 3 973.5345 5.88 38228 13260 2 973.535578 487.7745 Melanoma-associated antigen D4 OS=Homo sapiens OX=9606 GN=MAGED4 PE=1 SV=3 9.79 2947.4 - 528606 - - - 1.0919 - 1.537 0.355 - 117.3 1 2 0 0.0011 10 0 0 0 1.89E+07 3.22E+06 - - - 2.8625 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.13263.13263.2 0.673 14-Jul K.LVALNLDR.L "sp|Q9Y3D3|RT16_HUMAN,tr|A6ND22|A6ND22_HUMAN" 2 912.5393 1.22 38230 13263 2 912.54021 457.2769 "28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1" 5.84 2947.7 - 923805 - - - 1.0345 - 1.501 0.168 - 118.7 1 2 0 0.0009 8 0 0 0 8.86E+07 7.24E+07 - - - 1.5064 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.13271.13271.2 0.267 12-Jul K.IVVLLQR.L "sp|Q06323|PSME1_HUMAN,tr|H0YLU2|H0YLU2_HUMAN" 2 839.5593 1.44 38234 13271 2 839.56011 420.7869 Proteasome activator complex subunit 1 OS=Homo sapiens OX=9606 GN=PSME1 PE=1 SV=1 9.75 2948.8 - 732489 - - - 0.997 - 1.611 0.294 - 157.5 1 2 0 0.0008 7 0 0 0 3.33E+07 2.31E+07 - - - 2.7232 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.13278.13278.2 0.165 14-Aug R.ILEVLPGR.R sp|Q9UI43|MRM2_HUMAN 1 895.5491 2.73 38238 13278 2 895.551978 448.7818 "rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1" 6 2949.8 - 332743 - - - 3.2114 - 1.659 0.208 - 170.6 1 2 0 0.0029 8 0 0 0 6.27E+07 2.29E+07 - - - 2.1031 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.13281.13281.2 9.55 12-Aug K.LLDIVAR[166.11].S sp|Q12931|TRAP1_HUMAN 1 808.5046 2.15 38239 13281 2 808.505822 405.2596 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.84 2950.2 - 2.41E+06 - - - 1.5003 - 1.725 0.09 - 201.6 1 2 0 0.0012 7 0 0 0 3.10E+08 1.44E+08 - - - 1.4329 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.13282.13282.2 0.00955 12-Jul K.YVIYIER.V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 954.5175 0.8 38240 13282 2 954.518585 478.266 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 6 2950.2 - 1.93E+06 - - - 1.1702 - 1.472 0.305 - 223.2 1 2 0 0.0011 7 0 0 0 1.05E+09 1.32E+09 - - - 2.5184 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.13290.13290.2 0.00499 12-Jun R.VVFQEFR[166.11].Q sp|P35579|MYH9_HUMAN 1 933.4948 0.89 38245 13290 2 933.495347 467.7547 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2951.3 - 1.04E+06 - - - 0.616 - 1.348 0.357 - 156 1 2 0 0.0006 7 0 0 0 2.54E+08 2.85E+08 - - - 2.6238 0.9957 230117_WJC_METTL3_WT_vs_EV_F05.13294.13294.2 1.41 12-Jun K.ELVVLPR.E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 824.512 0.5 38246 13294 2 824.513303 413.2633 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2951.9 - 882316 - - - 1.5937 - 1.334 0.155 - 183.5 1 2 0 0.0013 7 0 0 0 1.83E+08 3.66E+08 - - - 1.0985 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.13297.13297.2 0.276 14-Jul R.ILEVLPGR[166.11].R sp|Q9UI43|MRM2_HUMAN 1 905.5574 2.7 38248 13297 2 905.558013 453.786 "rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1" 6 2952.2 - 449702 - - - 0.7079 - 1.403 0.205 - 124.4 1 2 0 0.0006 8 0 0 0 6.19E+07 2.29E+07 - - - 1.5762 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.13304.13304.2 0.0426 12-Jul R.VVFQEFR.Q sp|P35579|MYH9_HUMAN 1 923.4865 0.89 38250 13304 2 923.487539 462.7505 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2953.2 - 1.84E+06 - - - 1.1229 - 1.213 0.29 - 200.1 1 2 0 0.001 7 0 0 0 2.54E+08 2.86E+08 - - - 1.7945 0.9834 230117_WJC_METTL3_WT_vs_EV_F05.13305.13305.2 2.06 12-Apr K.IYLSYYR.S sp|Q8N1B4|VPS52_HUMAN 1 976.5018 0.63 38251 13305 2 976.503768 489.2582 Vacuolar protein sorting-associated protein 52 homolog OS=Homo sapiens OX=9606 GN=VPS52 PE=1 SV=1 8.5 2953.4 - 344485 - - - 1.9969 - 1.079 0.16 - 45 4 2 0 0.0019 7 0 0 0 2.19E+07 3.45E+07 - - - 0.1941 0.9829 230117_WJC_METTL3_WT_vs_EV_F05.13313.13313.2 2.5 12-Aug R.IGLLDPR.W "sp|Q15459|SF3A1_HUMAN,tr|H7C1L2|H7C1L2_HUMAN" 2 782.465 1.34 38254 13313 2 782.465623 392.2398 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 5.84 2954.4 - 4.25E+06 - - - 0.7476 - 1.157 0.089 - 211.9 1 2 0 0.0006 7 0 0 0 3.33E+08 2.48E+08 - - - 0.1602 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.13316.13316.2 0.0675 14-Jul R.LLSTYLER.Y "sp|Q12769|NU160_HUMAN,tr|G3V198|G3V198_HUMAN" 2 993.5495 1.32 38255 13316 2 993.552836 497.782 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 6 2954.8 - 802945 - - - 3.3617 - 1.666 0.323 - 132.2 1 2 0 0.0033 8 0 0 0 6.36E+07 4.84E+07 - - - 2.965 0.9962 230117_WJC_METTL3_WT_vs_EV_F05.13319.13319.2 0.217 14-Sep R.LLSTYLER[166.11].Y "sp|Q12769|NU160_HUMAN,tr|G3V198|G3V198_HUMAN" 2 1003.5578 1.35 38256 13319 2 1003.562385 502.7862 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 6 2955.2 - 734312 - - - 4.6026 - 1.582 0.317 - 243.3 1 2 0 0.0046 8 0 0 0 6.36E+07 4.72E+07 - - - 2.7643 0.9523 230117_WJC_METTL3_WT_vs_EV_F05.13339.13339.2 0.728 12-Apr R.YLLAMER.H "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 894.4633 3.11 38258 13339 2 894.464229 448.2389 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 2958.5 - 795072 - - - 1.0118 - 1.049 0.077 - 47.2 5 2 0 0.0009 7 0 0 0 3.56E+07 1.14E+07 - - - -0.5512 0.999 230117_WJC_METTL3_WT_vs_EV_F05.13342.13342.2 0.393 14-Sep R.LGALALPR[166.11].G "sp|Q6SPF0|SAMD1_HUMAN,tr|E9PIW9|E9PIW9_HUMAN" 2 819.5206 2.1 38259 13342 2 819.521941 410.7676 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.75 2958.9 - 1.67E+06 - - - 1.6449 - 1.922 0.191 - 299.2 1 2 0 0.0013 8 0 0 0 1.82E+08 8.65E+07 - - - 2.4218 0.9789 230117_WJC_METTL3_WT_vs_EV_F05.13344.13344.2 7.01 14-May R.LFVGSIPK[136.11].S "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 867.5309 0.91 38260 13344 2 867.531472 434.7727 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.75 2959.1 - 2.15E+06 - - - 0.6132 - 1.244 0.112 - 45.7 12 2 0 0.0005 8 0 0 0 1.26E+09 1.39E+09 - - - 0.0445 0.9957 230117_WJC_METTL3_WT_vs_EV_F05.13360.13360.2 0.946 14-Jul K.LLIIGPQK.T "sp|P52848|NDST1_HUMAN,tr|E7EVJ3|E7EVJ3_HUMAN" 2 880.5746 0.88 38269 13360 2 880.574322 441.2946 Bifunctional heparan sulfate N-deacetylase\N-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=NDST1 PE=1 SV=1 8.75 2961.1 - 528547 - - - -0.3032 - 1.463 0.183 - 139.5 1 2 0 -0.0003 8 0 0 0 1.67E+07 1.89E+07 - - - 1.5401 0.9935 230117_WJC_METTL3_WT_vs_EV_F05.13362.13362.2 0.234 12-Jun K.IFTFAEK[136.11].Y "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 4 862.468 0.63 38271 13362 2 862.467965 432.2413 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 6 2961.3 - 1.80E+06 - - - -0.0464 - 1.215 0.194 - 70.1 1 2 0 0 7 0 0 0 3.83E+07 6.04E+07 - - - 1.0909 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.13366.13366.2 1.69 12-Jun R.EALGLLR[166.11].A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 780.4733 1.11 38273 13366 2 780.474639 391.2439 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2961.8 - 2.46E+06 - - - 1.7054 - 1.328 0.185 - 142.5 1 2 0 0.0013 7 0 0 0 1.83E+08 1.65E+08 - - - 1.3058 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.13367.13367.2 0.518 12-Jun R.EALGLLR.A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 770.465 1.11 38274 13367 2 770.466147 386.2398 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2961.8 - 1.95E+06 - - - 1.4394 - 1.298 0.192 - 160.5 1 2 0 0.0011 7 0 0 0 1.83E+08 1.65E+08 - - - 1.2852 0.9565 230117_WJC_METTL3_WT_vs_EV_F05.13371.13371.2 0.0895 12-Oct K.PSVYFIK[136.11].F "sp|Q99865|SPI2A_HUMAN,sp|Q56A73|SPIN4_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 9 860.4887 0.5 38276 13371 2 860.490185 431.2516 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 9.01 2962.4 - 2.05E+06 - - - 1.6781 - 1.686 0.322 - 297.7 1 1 0 0.0014 7 0 0 0 2.30E+08 4.61E+08 - - - 3.074 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.13374.13374.2 0.0121 14-Jul K.MMMVLGAK.W "sp|Q14839|CHD4_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|F5H6N4|F5H6N4_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 17 879.438 1.15 38279 13374 2 879.440757 440.7263 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.5 2962.7 - 529957 - - - 3.0929 - 1.324 0.291 - 135 1 2 0 0.0027 8 0 0 0 1.88E+07 1.63E+07 - - - 2.0359 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.13384.13384.2 0.000964 24-Jul K.VIDPATATSVDLR.D sp|P50991|TCPD_HUMAN 1 1356.7249 999 38285 13384 2 1356.728734 679.3697 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 2964 - 159892 - - - 2.8296 - 1.673 0.396 - 120.4 1 2 0 0.0038 13 0 0 0 7.41E+06 0.00E+00 - - - 3.2854 0.9896 230117_WJC_METTL3_WT_vs_EV_F05.13388.13388.2 0.27 16-Aug R.ILVGTNLVR.L sp|Q96QK1|VPS35_HUMAN 1 983.6128 1.9 38287 13388 2 983.614959 492.8137 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 9.75 2964.5 - 1.98E+06 - - - 2.2306 - 1.395 0.078 - 155.9 1 2 0 0.0022 9 0 0 0 6.67E+07 3.51E+07 - - - 0.5795 0.9762 230117_WJC_METTL3_WT_vs_EV_F05.13389.13389.2 0.00508 12-Sep K.PSVYFIK.F "sp|Q99865|SPI2A_HUMAN,sp|Q56A73|SPIN4_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 9 852.4745 0.5 38288 13389 2 852.47548 427.2445 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 9.01 2964.5 - 2.51E+06 - - - 1.1015 - 2.05 0.375 - 274.5 1 1 0 0.0009 7 0 0 0 2.30E+08 4.61E+08 - - - 4.085 0.9942 230117_WJC_METTL3_WT_vs_EV_F05.13390.13390.2 0.731 12-Jul K.QLLYLEK.Y "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 3 905.5222 0.92 38289 13390 2 905.524328 453.7684 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 6 2964.6 - 1.30E+06 - - - 2.329 - 1.278 0.165 - 167.6 1 2 0 0.0021 7 0 0 0 5.57E+07 6.04E+07 - - - 1.0363 0.8872 230117_WJC_METTL3_WT_vs_EV_F05.13391.13391.2 0.0412 16-Aug K.LLNYAPLEK.- sp|P62875|RPAB5_HUMAN 1 1059.5964 1.23 38290 13391 2 1059.604346 530.8055 "DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1" 6 2964.7 - 385082 - - - 7.4547 - 1.463 0.142 - 174.7 1 2 0 0.0079 9 0 0 0 1.66E+07 1.35E+07 - - - 1.1881 0.9963 230117_WJC_METTL3_WT_vs_EV_F05.13396.13396.2 0.09 12-Jun K.ELVVLPR[166.11].E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 834.5203 0.49 38293 13396 2 834.522139 418.2674 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2965.4 - 3.66E+06 - - - 2.2528 - 1.308 0.201 - 183.5 1 2 0 0.0019 7 0 0 0 1.80E+08 3.65E+08 - - - 1.3758 0.9819 230117_WJC_METTL3_WT_vs_EV_F05.13399.13399.2 0.37 22-Jun R.LLSASPVDAAIR[166.11].V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1221.6957 6.3 38296 13399 2 1221.703124 611.8551 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 5.84 2965.8 - 98888.4 - - - 6.112 - 1.339 0.32 - 87.4 1 2 0 0.0075 12 0 0 0 5.83E+06 9.26E+05 - - - 2.1703 0.999 230117_WJC_METTL3_WT_vs_EV_F05.13400.13400.2 4.31E-05 20-Jul K.NFYYAAVPSAR.N sp|Q10471|GALT2_HUMAN 1 1257.6142 0.97 38297 13400 2 1257.613455 629.8144 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.59 2965.9 - 86947.8 - - - -0.6099 - 1.532 0.416 - 103.2 1 2 0 -0.0008 11 0 0 0 8.77E+05 9.01E+05 - - - 3.2673 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.13409.13409.2 0.00361 20-Jun K.NFYYAAVPSAR[166.11].N sp|Q10471|GALT2_HUMAN 1 1267.6225 0.97 38301 13409 2 1267.627427 634.8185 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.59 2967 - 74205.2 - - - 3.8931 - 1.382 0.385 - 79 1 2 0 0.0049 11 0 0 0 8.77E+05 9.01E+05 - - - 2.7583 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.13414.13414.2 0.000306 20-Sep K.QAGVFEPTIVK.V "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1187.655 267.13 38304 13414 2 1187.658549 594.8348 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2967.6 - 280326 - - - 2.968 - 1.73 0.409 - 230.3 1 2 0 0.0035 11 0 0 0 1.59E+07 5.96E+04 - - - 3.5436 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.13418.13418.2 0.0524 16-Sep R.IVDPEIALK.L "sp|P33240|CSTF2_HUMAN,tr|A0A0A0MT56|A0A0A0MT56_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 996.5855 2.87 38306 13418 2 996.588212 499.3001 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.37 2968.1 - 1.23E+06 - - - 2.6731 - 1.724 0.369 - 174.8 1 2 0 0.0027 9 0 0 0 9.09E+08 3.17E+08 - - - 3.3413 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.13425.13425.2 0.672 14-Oct K.IADFGLAR[166.11].L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 871.4791 1.97 38310 13425 2 871.480605 436.7468 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2968.9 - 1.02E+06 - - - 1.7017 - 1.63 0.18 - 322.3 1 2 0 0.0015 8 0 0 0 9.04E+08 4.58E+08 - - - 1.8435 0.9841 230117_WJC_METTL3_WT_vs_EV_F05.13432.13432.2 0.0346 16-Sep K.VVLLTEVDK.L sp|P40938|RFC3_HUMAN 1 1014.5961 1.81 38314 13432 2 1014.603146 508.3053 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 4.37 2969.7 - 250603 - - - 6.9328 - 1.667 0.321 - 205.2 1 2 0 0.007 9 0 0 0 4.57E+07 2.53E+07 - - - 2.8881 0.9254 230117_WJC_METTL3_WT_vs_EV_F05.13444.13444.2 0.0945 12-Aug P.FPAALLR[166.11].V "sp|Q9H0D2|ZN541_HUMAN,sp|Q9UJV9|DDX41_HUMAN,tr|H7BXG6|H7BXG6_HUMAN,tr|M0R167|M0R167_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|A0A075B6F0|A0A075B6F0_HUMAN,tr|H0Y8L8|H0Y8L8_HUMAN" 7 796.4835 1.13 38320 13444 2 796.484283 399.249 Zinc finger protein 541 OS=Homo sapiens OX=9606 GN=ZNF541 PE=1 SV=3 9.75 2971.2 - 2.38E+06 - - - 1.0094 - 1.533 0.271 - 290.5 1 1 0 0.0008 7 0 0 0 3.82E+08 3.38E+08 - - - 2.396 0.9943 230117_WJC_METTL3_WT_vs_EV_F05.13452.13452.2 1.23 12-Aug R.FILIQNR.A "sp|P53680|AP2S1_HUMAN,tr|M0R0N4|M0R0N4_HUMAN,tr|X6R390|X6R390_HUMAN,tr|M0QYZ2|M0QYZ2_HUMAN" 4 902.5338 1.2 38325 13452 2 902.532778 452.2742 AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2 9.75 2972.2 - 1.02E+06 - - - -1.118 - 1.61 0.162 - 209.3 1 2 0 -0.001 7 0 0 0 4.01E+07 3.34E+07 - - - 1.7462 0.9959 230117_WJC_METTL3_WT_vs_EV_F05.13457.13457.2 0.376 14-Oct K.IADFGLAR.L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 861.4709 1.97 38328 13457 2 861.468654 431.7427 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2972.8 - 1.27E+07 - - - -2.5515 - 1.943 0.273 - 321.1 1 2 0 -0.0022 8 0 0 0 9.00E+08 4.58E+08 - - - 3.06 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.13458.13458.2 0.0754 14-Aug K.LLQLVEDR.G "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 984.5604 0.5 38329 13458 2 984.562471 493.2875 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 2973 - 953134 - - - 2.1086 - 1.714 0.222 - 222.3 1 2 0 0.0021 8 0 0 0 1.47E+08 2.92E+08 - - - 2.3051 0.9799 230117_WJC_METTL3_WT_vs_EV_F05.13465.13465.2 0.00764 16-Oct K.PLYVALAQR[166.11].K "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PIK9|A0A6I8PIK9_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 25 1039.6054 1.11 38333 13465 2 1039.606877 520.81 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.18 2973.8 - 258007 - - - 1.4352 - 1.96 0.478 - 382.7 1 1 0 0.0015 9 0 0 0 3.97E+08 3.57E+08 - - - 4.5179 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.13478.13478.2 0.0281 12-Jul R.YFEPLVK.K "sp|Q7L590|MCM10_HUMAN,tr|Q5T670|Q5T670_HUMAN" 2 894.4851 3.75 38339 13478 2 894.486862 448.2498 Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2 6 2975.5 - 413113 - - - 1.9643 - 1.29 0.199 - 147.7 1 2 0 0.0018 7 0 0 0 1.06E+08 2.83E+07 - - - 1.3171 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.13516.13516.2 0.152 14-Aug R.LLAFAEAR.A "sp|Q8WUY8|NAT14_HUMAN,sp|Q99519|NEUR1_HUMAN,tr|M0R1E3|M0R1E3_HUMAN,tr|E9PIF4|E9PIF4_HUMAN" 4 889.5022 2.1 38353 13516 2 889.501123 445.7584 Probable N-acetyltransferase 14 OS=Homo sapiens OX=9606 GN=NAT14 PE=1 SV=1 6 2980.7 - 1.83E+06 - - - -1.1568 - 1.709 0.28 - 181.5 1 2 0 -0.001 8 0 0 0 6.13E+07 2.92E+07 - - - 2.725 0.9828 230117_WJC_METTL3_WT_vs_EV_F05.13517.13517.2 2.52 14-Oct R.LAVEALVR[166.11].T "sp|Q92839|HYAS1_HUMAN,tr|M0QXH4|M0QXH4_HUMAN,tr|G3V1S7|G3V1S7_HUMAN,tr|M0R2V0|M0R2V0_HUMAN" 4 879.5417 7.27 38354 13517 2 879.540953 440.7781 Hyaluronan synthase 1 OS=Homo sapiens OX=9606 GN=HAS1 PE=1 SV=2 6 2980.9 - 1.23E+06 - - - -0.8743 - 1.613 0.052 - 399.9 2 2 0 -0.0008 8 0 0 0 6.02E+09 8.29E+08 - - - 0.7323 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.13518.13518.2 0.0279 18-Nov K.LAELEEALQK.A "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1142.6183 40.79 38355 13518 2 1142.620464 572.3164 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.25 2981 - 423532 - - - 1.8904 - 2.347 0.339 - 364.7 1 2 0 0.0022 10 0 0 0 8.68E+06 2.13E+05 - - - 3.9255 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.13537.13537.2 0.0421 14-Sep K.IINDLLAR.S "sp|P51530|DNA2_HUMAN,tr|F8VR31|F8VR31_HUMAN,tr|H0Y455|H0Y455_HUMAN" 3 926.5549 3.41 38364 13537 2 926.553736 464.2847 DNA replication ATP-dependent helicase\nuclease DNA2 OS=Homo sapiens OX=9606 GN=DNA2 PE=1 SV=3 5.84 2983.4 - 572407 - - - -1.2735 - 1.541 0.239 - 180 1 2 0 -0.0012 8 0 0 0 2.54E+07 7.44E+06 - - - 2.1101 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.13541.13541.2 0.0385 14-Jul K.LLQPLVPR.Y sp|Q8N8A6|DDX51_HUMAN 1 934.5964 1.05 38366 13541 2 934.595819 468.3055 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2983.8 - 461828 - - - -0.6077 - 1.371 0.281 - 141.1 1 2 0 -0.0006 8 0 0 0 9.42E+07 8.94E+07 - - - 2.0679 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.13543.13543.2 0.0484 12-Jul K.C[160.03]FLTAMR.E "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN" 3 897.4201 1.9 38367 13543 2 897.420273 449.7173 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 8.25 2984 - 1.07E+06 - - - 0.2162 - 1.297 0.206 - 179.3 1 2 0 0.0002 7 0 0 0 4.31E+07 2.26E+07 - - - 1.3865 0.962 230117_WJC_METTL3_WT_vs_EV_F05.13545.13545.2 1.76 12-Jun R.YLDELMK[136.11].L "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 918.4612 1.43 38369 13545 2 918.460207 460.2379 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 2984.2 - 893890 - - - -1.0866 - 1.132 0.141 - 89.1 3 2 0 -0.001 7 0 0 0 3.96E+07 2.77E+07 - - - 0.2618 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.13549.13549.2 0.0763 14-Jun K.ILDVMYSR[166.11].L sp|P78527|PRKDC_HUMAN 1 1005.5193 1.03 38370 13549 2 1005.518935 503.7669 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2984.8 - 712530 - - - -0.3352 - 1.232 0.282 - 60.5 1 2 0 -0.0003 8 0 0 0 7.66E+07 7.47E+07 - - - 1.753 0.9936 230117_WJC_METTL3_WT_vs_EV_F05.13551.13551.2 0.302 12-Jul K.ILEVDLK[136.11].N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 836.5099 0.81 38371 13551 2 836.508997 419.2622 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2985 - 2.63E+06 - - - -1.0436 - 1.54 0.161 - 139.2 1 2 0 -0.0009 7 0 0 0 2.91E+08 3.58E+08 - - - 1.598 0.996 230117_WJC_METTL3_WT_vs_EV_F05.13565.13565.2 0.108 14-Jul K.LLQPLVPR[166.11].Y sp|Q8N8A6|DDX51_HUMAN 1 944.6047 1.06 38376 13565 2 944.605321 473.3096 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2986.8 - 1.25E+06 - - - 0.7029 - 1.224 0.211 - 143.2 1 2 0 0.0007 8 0 0 0 9.43E+07 8.94E+07 - - - 1.2088 0.9964 230117_WJC_METTL3_WT_vs_EV_F05.13576.13576.2 0.5 12-Jul K.ILEVDLK.N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 828.4957 0.79 38381 13576 2 828.496058 415.2551 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2988.2 - 7.59E+06 - - - 0.4683 - 1.554 0.125 - 135 1 2 0 0.0004 7 0 0 0 2.84E+08 3.58E+08 - - - 1.3609 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.13585.13585.2 0.000612 18-Oct K.QQLLIGAYAK.A sp|Q99832|TCPH_HUMAN 1 1103.6339 11.28 38388 13585 2 1103.634893 552.8242 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.59 2989.3 - 319995 - - - 0.9043 - 1.752 0.4 - 259.1 1 2 0 0.001 10 0 0 0 8.27E+06 7.33E+05 - - - 3.5603 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.13588.13588.2 4.01 14-Jul K.LAVEAVLR.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 869.5335 7.27 38390 13588 2 869.534377 435.774 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 2989.6 - 1.41E+08 - - - 1.0638 - 1.686 0.256 - 211.4 1 2 0 0.0009 8 0 0 0 6.03E+09 8.29E+08 - - - 2.5069 0.995 230117_WJC_METTL3_WT_vs_EV_F05.13616.13616.2 2.98 12-Jun K.EAVLLLK[136.11].K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 792.52 0.75 38401 13616 2 792.520778 397.2673 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 2993.5 - 1.46E+06 - - - 0.9299 - 1.228 0.177 - 124.2 1 2 0 0.0007 7 0 0 0 6.18E+08 8.28E+08 - - - 0.9989 0.9939 230117_WJC_METTL3_WT_vs_EV_F05.13618.13618.2 0.265 14-Aug R.DLAPIGIR.V "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 853.5022 1.03 38403 13618 2 853.503836 427.7584 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 5.84 2993.7 - 660781 - - - 1.973 - 1.479 0.092 - 189.3 1 2 0 0.0017 8 0 0 0 2.07E+08 2.01E+08 - - - 0.9003 0.9934 230117_WJC_METTL3_WT_vs_EV_F05.13620.13620.2 0.593 12-May K.VLEILGK[136.11].K "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 10 778.5044 2.49 38405 13620 2 778.504706 390.2595 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.97 2994 - 408697 - - - 0.4046 - 1.292 0.18 - 51.1 4 2 0 0.0003 7 0 0 0 5.13E+07 2.06E+07 - - - 0.9132 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.13628.13628.2 1.79 12-Jul K.EAVLLLK.K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 784.5058 0.75 38409 13628 2 784.506927 393.2602 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 2995 - 1.92E+06 - - - 1.3843 - 1.487 0.173 - 188.7 1 2 0 0.0011 7 0 0 0 6.18E+08 8.28E+08 - - - 1.5756 0.9922 230117_WJC_METTL3_WT_vs_EV_F05.13632.13632.2 1.56 12-Aug R.LLQIIER[166.11].Y sp|P78527|PRKDC_HUMAN 1 893.5574 1.18 38411 13632 2 893.558666 447.786 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2995.5 - 2.46E+06 - - - 1.4481 - 1.513 0.04 - 225.9 1 2 0 0.0013 7 0 0 0 2.58E+08 2.18E+08 - - - 0.6481 0.9642 230117_WJC_METTL3_WT_vs_EV_F05.13638.13638.2 0.953 14-Aug R.IILLAEGR.L sp|P23526|SAHH_HUMAN 1 883.5491 1.18 38415 13638 2 883.552184 442.7818 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 6 2996.2 - 3.06E+06 - - - 3.4882 - 1.54 0 - 195.3 2 2 0 0.0031 8 0 0 0 2.58E+08 2.18E+08 - - - 0.2078 0.9912 230117_WJC_METTL3_WT_vs_EV_F05.13655.13655.2 0.0687 14-Jul K.AAFAPFGR[166.11].L "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 5 845.4423 1.37 38424 13655 2 845.445684 423.7284 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 9.79 2998.3 - 415840 - - - 3.9518 - 1.26 0.238 - 108.1 1 2 0 0.0033 8 0 0 0 2.23E+07 1.64E+07 - - - 1.4948 0.939 230117_WJC_METTL3_WT_vs_EV_F05.13658.13658.2 3.67 16-Jun K.IAVNIALER[166.11].F "sp|Q9H6S0|YTDC2_HUMAN,tr|D6RF50|D6RF50_HUMAN,tr|D6RA70|D6RA70_HUMAN" 3 1007.6003 0.62 38426 13658 2 1007.600466 504.8074 3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2 6 2998.6 - 204446 - - - 0.1647 - 1.131 0.027 - 62.8 2 2 0 0.0002 9 0 0 0 5.28E+06 8.52E+06 - - - -0.538 0.9425 230117_WJC_METTL3_WT_vs_EV_F05.13659.13659.2 0.00604 18-Oct T.LGSATALMIR[166.11].E "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 1041.588 1.03 38427 13659 2 1041.591342 521.8013 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 2998.8 - 257856 - - - 3.1884 - 2.059 0.356 - 207 1 1 0 0.0033 10 0 0 0 1.93E+07 1.88E+07 - - - 3.6853 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.13661.13661.2 0.000232 24-Sep K.FC[160.03]ADSDGFSQELR[166.11].N "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1540.6492 0.17 38429 13661 2 1540.649107 771.3319 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.03 2999 - 88910.8 - - - -0.0454 - 1.81 0.521 - 91.1 1 2 0 -0.0001 13 0 0 0 2.83E+05 1.62E+06 - - - 4.4119 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.13676.13676.2 0.131 14-Jul R.FIVLNPTR.F "sp|Q9NZW5|PALS2_HUMAN,tr|B8ZZG1|B8ZZG1_HUMAN" 2 958.56 3.85 38438 13676 2 958.561661 480.2873 Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2 PE=1 SV=2 9.75 3000.7 - 1.04E+06 - - - 1.7307 - 1.569 0.118 - 170.4 1 2 0 0.0017 8 0 0 0 5.25E+07 1.36E+07 - - - 1.2705 0.999 230117_WJC_METTL3_WT_vs_EV_F05.13692.13692.2 0.145 14-Aug R.NLLSVAYK.N "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB2|A2IDB2_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|K7EIT4|K7EIT4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 22 906.5175 1.54 38447 13692 2 906.518993 454.266 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 8.59 3002.6 - 1.59E+07 - - - 1.6823 - 1.528 0.287 - 260 1 2 0 0.0015 8 0 0 0 4.97E+08 3.23E+08 - - - 2.4389 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.13699.13699.3 0.0153 Sep-36 R.MVNHFIAEFK.R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1234.6169 12.36 38452 13699 3 1234.618909 412.5462 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 3003.3 - 1.85E+06 - - - 1.6556 - 1.525 0.287 - 69.6 1 2 0 0.002 10 0 0 0 4.25E+07 3.43E+06 - - - 2.9716 0.925 230117_WJC_METTL3_WT_vs_EV_F05.13708.13708.2 0.0465 14-Aug F.GPVLNYLR[166.11].H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 940.537 0.88 38458 13708 2 940.537542 471.2758 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3004.4 - 501839 - - - 0.6071 - 1.687 0.254 - 233.5 1 1 0 0.0006 8 0 0 0 3.90E+07 4.42E+07 - - - 2.4941 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.13715.13715.2 0.084 14-Sep R.FLGC[160.03]VDIK.D "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 950.4895 1.53 38463 13715 2 950.492113 476.252 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 5.83 3005.1 - 1.29E+06 - - - 2.7081 - 1.41 0.422 - 211.5 1 2 0 0.0026 8 0 0 0 4.02E+07 2.62E+07 - - - 3.1933 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.13721.13721.2 0.00124 22-Nov R.TVIIEQSWGSPK[136.11].V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1351.7227 2.35 38466 13721 2 1351.726683 676.8686 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 3005.9 - 228538 - - - 2.9348 - 2.251 0.422 - 335.1 1 2 0 0.004 12 0 0 0 1.32E+07 5.60E+06 - - - 4.2915 0.8762 230117_WJC_METTL3_WT_vs_EV_F05.13725.13725.2 0.0207 14-Jul F.GPVLNYLR.H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 930.5287 0.88 38468 13725 2 930.530241 466.2716 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3006.3 - 392575 - - - 1.655 - 1.584 0.192 - 186 1 1 0 0.0015 8 0 0 0 3.94E+07 4.49E+07 - - - 1.8458 0.9946 230117_WJC_METTL3_WT_vs_EV_F05.13727.13727.2 0.342 14-Jul R.LYELDGLR.E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 977.5182 0.02 38469 13727 2 977.519416 489.7664 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3006.5 - 159022 - - - 1.2481 - 1.248 0.163 - 127.6 1 2 0 0.0012 8 0 0 0 2.82E+06 1.65E+08 - - - 0.9127 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.13732.13732.2 0.0251 14-Sep K.LALDYGIK.F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 891.5066 2.76 38472 13732 2 891.508287 446.7606 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 3007.2 - 1.01E+07 - - - 1.9271 - 1.8 0.217 - 222.8 1 2 0 0.0017 8 0 0 0 4.29E+08 1.56E+08 - - - 2.416 0.9927 230117_WJC_METTL3_WT_vs_EV_F05.13733.13733.2 0.115 12-Jun K.MSILGVR.S "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|E9PM98|E9PM98_HUMAN,tr|A0A494BZW0|A0A494BZW0_HUMAN" 8 774.4422 1.8 38473 13733 2 774.443976 388.2284 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 9.5 3007.3 - 1.01E+06 - - - 2.2997 - 1.305 0.132 - 100.6 1 2 0 0.0018 7 0 0 0 3.75E+07 2.08E+07 - - - 0.8589 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.13734.13734.2 0.00668 22-Nov R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 2.35 38474 13734 2 1343.710988 672.8615 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 3007.4 - 559055 - - - 1.8397 - 1.95 0.38 - 142.8 1 2 0 0.0025 12 0 0 0 1.32E+07 5.60E+06 - - - 3.6041 0.9941 230117_WJC_METTL3_WT_vs_EV_F05.13737.13737.2 0.147 14-May R.FLGC[160.03]VDIK[136.11].D "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 958.5037 1.77 38475 13737 2 958.505033 480.2591 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 5.83 3007.8 - 853838 - - - 1.35 - 1.059 0.222 - 49.2 1 2 0 0.0013 8 0 0 0 3.95E+07 2.23E+07 - - - 0.8532 0.9918 230117_WJC_METTL3_WT_vs_EV_F05.13746.13746.2 0.881 18-Jul K.ILAEESYLYK.H sp|Q9NVX0|HAUS2_HUMAN 1 1227.6387 1.87 38482 13746 2 1227.642875 614.8266 HAUS augmin-like complex subunit 2 OS=Homo sapiens OX=9606 GN=HAUS2 PE=1 SV=1 4.53 3008.9 - 260188 - - - 3.3968 - 1.362 0.182 - 98.5 1 2 0 0.0042 10 0 0 0 4.22E+06 2.25E+06 - - - 1.2463 0.993 230117_WJC_METTL3_WT_vs_EV_F05.13750.13750.2 0.252 12-Jul R.ISPLQFR.- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 859.4916 2.95 38484 13750 2 859.492855 430.7531 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 3009.3 - 1.02E+07 - - - 1.4741 - 1.445 0.071 - 233.5 1 2 0 0.0013 7 0 0 0 3.21E+08 1.09E+08 - - - 0.7314 0.975 230117_WJC_METTL3_WT_vs_EV_F05.13752.13752.2 5.02 12-Jun R.ISPLQFR[166.11].- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 869.4999 2.95 38486 13752 2 869.5025 435.7572 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 3009.4 - 3.45E+06 - - - 3.0385 - 1.231 0.077 - 129.9 1 2 0 0.0026 7 0 0 0 3.22E+08 1.09E+08 - - - 0.2674 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.13760.13760.2 0.0426 12-Jul K.LVYILNR.D sp|Q15393|SF3B3_HUMAN 1 889.5385 1.44 38492 13760 2 889.540449 445.7765 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 3010.4 - 1.17E+07 - - - 2.1483 - 1.394 0.255 - 196.4 1 2 0 0.0019 7 0 0 0 2.81E+08 1.96E+08 - - - 1.9764 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.13761.13761.2 0.0557 12-Aug K.FTAILYR.T "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 882.4963 0.63 38493 13761 2 882.498442 442.2554 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.75 3010.4 - 6.34E+06 - - - 2.383 - 1.658 0.149 - 276.6 1 2 0 0.0021 7 0 0 0 1.26E+08 2.00E+08 - - - 1.7429 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.13763.13763.2 0.00758 14-Aug K.ITAFIVER[166.11].D "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 957.5523 0.62 38495 13763 2 957.554245 479.7834 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 6 3010.5 - 930184 - - - 2.0448 - 1.758 0.328 - 185.4 1 2 0 0.002 8 0 0 0 5.91E+07 9.52E+07 - - - 3.1645 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.13764.13764.2 0.0483 12-Jul R.YYFEGIK[136.11].Q "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN" 3 926.4629 2.3 38496 13764 2 926.462127 464.2387 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 6 3010.6 - 716205 - - - -0.8559 - 1.418 0.34 - 129.5 1 2 0 -0.0008 7 0 0 0 4.42E+07 1.92E+07 - - - 2.6586 0.9969 230117_WJC_METTL3_WT_vs_EV_F05.13770.13770.2 0.127 14-Jul K.ITAFIVER.D "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 947.544 0.51 38500 13770 2 947.545583 474.7793 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 6 3011.3 - 1.10E+06 - - - 1.6527 - 1.37 0.185 - 108.5 1 2 0 0.0016 8 0 0 0 4.94E+07 9.60E+07 - - - 1.3564 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.13774.13774.2 0.149 14-Jun K.VLVPQIPR[166.11].L sp|Q10469|MGAT2_HUMAN 1 930.589 1.13 38502 13774 2 930.59004 466.3018 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 3011.9 - 880888 - - - 1.11 - 1.388 0.25 - 116 1 2 0 0.001 8 0 0 0 9.70E+07 8.60E+07 - - - 1.876 0.9507 230117_WJC_METTL3_WT_vs_EV_F05.13780.13780.2 3.18 12-Jul R.LLAELVR.A "sp|A5YM72|CRNS1_HUMAN,sp|Q7Z6Z7|HUWE1_HUMAN" 2 812.512 2.43 38506 13780 2 812.515849 407.2633 Carnosine synthase 1 OS=Homo sapiens OX=9606 GN=CARNS1 PE=1 SV=3 6 3012.6 - 1.24E+06 - - - 4.7507 - 1.302 0.094 - 117.4 1 2 0 0.0039 7 0 0 0 6.72E+07 2.76E+07 - - - 0.5703 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.13782.13782.2 0.0355 12-Jul K.FYIDPYK[136.11].L sp|Q9NY12|GAR1_HUMAN 1 952.4786 0.81 38508 13782 2 952.480435 477.2466 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3012.8 - 1.28E+06 - - - 1.958 - 1.299 0.366 - 186 1 2 0 0.0019 7 0 0 0 1.21E+09 1.50E+09 - - - 2.5726 0.9905 230117_WJC_METTL3_WT_vs_EV_F05.13790.13790.2 0.244 14-Jun K.VLVPQIPR.L sp|Q10469|MGAT2_HUMAN 1 920.5807 1.13 38514 13790 2 920.582856 461.2976 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 3013.7 - 1.30E+06 - - - 2.3018 - 1.2 0.146 - 108.7 1 2 0 0.0021 8 0 0 0 9.73E+07 8.60E+07 - - - 0.6686 0.999 230117_WJC_METTL3_WT_vs_EV_F05.13791.13791.2 0.114 18-Oct R.YPVNSVNILK.A "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1145.6445 21.58 38515 13791 2 1145.647694 573.8295 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.59 3013.9 - 477019 - - - 2.8237 - 1.834 0.302 - 161.2 1 2 0 0.0032 10 0 0 0 1.63E+07 7.53E+05 - - - 2.9635 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.13796.13796.2 0.00987 14-Jul R.VIFTSPIK[136.11].A sp|P42285|MTREX_HUMAN 1 911.5572 1.1 38518 13796 2 911.559018 456.7859 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 8.72 3014.4 - 1.04E+06 - - - 2.0449 - 1.473 0.288 - 148.7 1 2 0 0.0019 8 0 0 0 1.13E+08 1.02E+08 - - - 2.3357 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.13808.13808.2 24.4 12-Jul R.LVQLLVK.A sp|P14923|PLAK_HUMAN 1 811.5531 17.99 38525 13808 2 811.554397 406.7838 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 8.75 3015.8 - 3.84E+06 - - - 1.5674 - 1.721 0.07 - 124.1 1 2 0 0.0013 7 0 0 0 2.58E+08 1.44E+07 - - - 1.2778 0.999 230117_WJC_METTL3_WT_vs_EV_F05.13809.13809.2 0.0312 16-Aug R.VLLLEAGPK.D "sp|Q8NE62|CHDH_HUMAN,tr|C9J7D8|C9J7D8_HUMAN,tr|C9JYW4|C9JYW4_HUMAN" 3 938.5801 5.1 38526 13809 2 938.581596 470.2973 "Choline dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=CHDH PE=1 SV=2" 5.97 3015.9 - 551198 - - - 1.628 - 1.449 0.313 - 147.6 1 2 0 0.0015 9 0 0 0 1.63E+07 3.19E+06 - - - 2.4253 0.9922 230117_WJC_METTL3_WT_vs_EV_F05.13814.13814.2 1.14 12-Jul K.LLNVVK[136.11]V.- sp|P17028|ZNF24_HUMAN 1 791.536 1.68 38529 13814 2 791.537299 396.7753 Zinc finger protein 24 OS=Homo sapiens OX=9606 GN=ZNF24 PE=1 SV=4 8.75 3016.6 - 1.03E+06 - - - 1.6095 - 1.367 0.085 - 110.5 1 2 0 0.0013 7 0 0 0 4.13E+07 2.46E+07 - - - 0.659 0.9926 230117_WJC_METTL3_WT_vs_EV_F05.13824.13824.2 0.0913 16-Jun R.VPPEFLVQR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1093.616 1.5 38537 13824 2 1093.617628 547.8153 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3017.8 - 263988 - - - 1.5344 - 1.172 0.161 - 99.4 1 2 0 0.0017 9 0 0 0 4.26E+07 2.85E+07 - - - 0.6888 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.13828.13828.2 0.00173 12-Jun K.LFEMAYK.K "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 900.4415 4.43 38539 13828 2 900.443318 451.228 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6 3018.3 - 5.69E+06 - - - 1.9901 - 1.395 0.429 - 131.2 1 2 0 0.0018 7 0 0 0 1.26E+09 2.83E+08 - - - 3.2638 0.9944 230117_WJC_METTL3_WT_vs_EV_F05.13833.13833.2 0.35 14-Aug R.LPWAVAGR.S sp|Q8NBX0|SCPDL_HUMAN 1 868.4919 1.14 38542 13833 2 868.492648 435.2532 Saccharopine dehydrogenase-like oxidoreductase OS=Homo sapiens OX=9606 GN=SCCPDH PE=1 SV=1 9.75 3018.8 - 914939 - - - 0.8359 - 1.48 0.096 - 204.2 1 2 0 0.0007 8 0 0 0 3.00E+07 2.64E+07 - - - 0.9322 0.9841 230117_WJC_METTL3_WT_vs_EV_F05.13840.13840.2 2.1 12-Jun R.TIPVVFK.D "sp|P25685|DNJB1_HUMAN,tr|A0A7I2V3K7|A0A7I2V3K7_HUMAN" 2 802.4953 0.69 38544 13840 2 802.496703 402.2549 DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4 8.41 3019.8 - 1.61E+06 - - - 1.7782 - 1.166 0.089 - 113.9 1 2 0 0.0014 7 0 0 0 4.80E+07 6.92E+07 - - - 0.1845 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.13842.13842.2 0.117 12-Jun K.LFEMAYK[136.11].K "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 908.4557 4.43 38545 13842 2 908.457083 455.2351 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6 3020 - 4.10E+06 - - - 1.4937 - 1.371 0.331 - 113.7 1 2 0 0.0014 7 0 0 0 1.26E+09 2.83E+08 - - - 2.4851 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.13846.13846.2 0.0142 16-Jun R.IIFSPVAPK[136.11].E sp|O15294|OGT1_HUMAN 1 978.5994 1.33 38547 13846 2 978.602493 490.307 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 8.75 3020.5 - 787691 - - - 3.2076 - 1.186 0.344 - 59.7 1 2 0 0.0031 9 0 0 0 9.15E+07 6.87E+07 - - - 2.0743 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.13856.13856.2 0.00179 18-Aug K.VLQSALAAIR.H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1040.6342 1.04 38553 13856 2 1040.634605 521.3244 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 3021.6 - 717928 - - - 0.3613 - 1.894 0.358 - 154.7 1 2 0 0.0004 10 0 0 0 2.80E+08 2.68E+08 - - - 3.4679 0.8745 230117_WJC_METTL3_WT_vs_EV_F05.13857.13857.2 5.29 12-May R.NLVSYLK.Q "sp|Q96T37|RBM15_HUMAN,sp|Q8NDT2|RB15B_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 5 835.4804 0.58 38554 13857 2 835.482043 418.7475 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 8.59 3021.7 - 655726 - - - 2.0216 - 0.98 0.013 - 63.3 3 2 0 0.0017 7 0 0 0 2.76E+07 4.73E+07 - - - -1.1407 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.13862.13862.2 0.0223 18-Aug K.VLQSALAAIR[166.11].H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1050.6425 1.04 38557 13862 2 1050.642803 526.3285 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 3022.3 - 1.36E+06 - - - 0.2893 - 2.035 0.362 - 179.1 1 2 0 0.0003 10 0 0 0 2.80E+08 2.68E+08 - - - 3.6978 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.13863.13863.2 0.00716 12-Jun R.FFTPAIR.Q "sp|Q8TDP1|RNH2C_HUMAN,tr|E9PN81|E9PN81_HUMAN" 2 850.4701 0.76 38558 13863 2 850.470904 426.2423 Ribonuclease H2 subunit C OS=Homo sapiens OX=9606 GN=RNASEH2C PE=1 SV=1 9.75 3022.4 - 1.29E+06 - - - 0.9171 - 1.373 0.36 - 116.3 1 2 0 0.0008 7 0 0 0 7.57E+07 1.00E+08 - - - 2.7041 0.9126 230117_WJC_METTL3_WT_vs_EV_F05.13864.13864.2 3.81 16-Aug R.IIFSPVAPK.E sp|O15294|OGT1_HUMAN 1 970.5852 1.33 38559 13864 2 970.589486 486.2999 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 8.75 3022.5 - 1.20E+06 - - - 4.4633 - 1.383 0.006 - 150.4 1 2 0 0.0043 9 0 0 0 9.10E+07 6.83E+07 - - - 0.022 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.13873.13873.2 0.152 14-Nov K.IAADILIK.E "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 855.543 0.92 38564 13873 2 855.541826 428.7788 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.84 3023.6 - 525144 - - - -1.3185 - 1.737 0.285 - 235.6 1 2 0 -0.0011 8 0 0 0 1.66E+07 1.80E+07 - - - 2.8109 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.13874.13874.2 0.0707 14-Jul R.YPEEFALR.D "sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN" 4 1023.5025 0.49 38565 13874 2 1023.503853 512.7585 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.53 3023.7 - 421989 - - - 1.277 - 1.162 0.297 - 133.8 1 2 0 0.0013 8 0 0 0 1.74E+07 3.58E+07 - - - 1.6871 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.13885.13885.2 0.00335 16-Sep R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 999 38572 13885 2 1030.59289 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 3025.1 - 3.10E+07 - - - 1.8077 - 1.903 0.415 - 221.7 1 2 0 0.0019 9 0 0 0 5.21E+09 0.00E+00 - - - 3.9671 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.13890.13890.2 0.00639 20-Aug R.LLADPTGAFGK.E sp|P30044|PRDX5_HUMAN 1 1088.5866 3.48 38575 13890 2 1088.588508 545.3006 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.84 3025.7 - 227988 - - - 1.7435 - 1.79 0.442 - 117.9 1 2 0 0.0019 11 0 0 0 2.62E+07 7.53E+06 - - - 3.88 0.9835 230117_WJC_METTL3_WT_vs_EV_F05.13895.13895.2 0.211 12-May R.FPPYYMR[166.11].R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 982.461 0.88 38576 13895 2 982.463803 492.2378 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 3026.5 - 366963 - - - 2.8235 - 0.926 0.226 - 60.6 1 2 0 0.0028 7 0 0 0 7.83E+06 8.91E+06 - - - 0.4658 1 230117_WJC_METTL3_WT_vs_EV_F05.13897.13897.2 1.67E-05 28-Nov K.NQVALNPQNTVFDAK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1657.8424 999 38577 13897 2 1657.84593 829.9285 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3026.7 - 136265 - - - 2.1389 - 2.256 0.513 - 197.7 1 2 0 0.0035 15 0 0 0 5.53E+06 0.00E+00 - - - 4.8292 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.13899.13899.2 0.0119 18-Oct K.LAEALYIADR.K "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1133.6081 1.4 38579 13899 2 1133.609749 567.8113 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 3026.9 - 398672 - - - 1.4776 - 2.426 0.37 - 358.3 1 2 0 0.0017 10 0 0 0 6.59E+07 4.71E+07 - - - 4.2471 0.9543 230117_WJC_METTL3_WT_vs_EV_F05.13902.13902.2 3.03 12-Jun K.TISLVIR[166.11].G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 810.5203 1.54 38580 13902 2 810.522064 406.2674 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 9.41 3027.3 - 603640 - - - 2.227 - 1.106 0.03 - 95.2 1 2 0 0.0018 7 0 0 0 5.34E+07 3.46E+07 - - - -0.4188 0.8641 230117_WJC_METTL3_WT_vs_EV_F05.13918.13918.2 0.0507 12-Jun K.SAEFLLH.M "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 815.4178 - 38588 13918 2 815.418776 408.7162 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 5.22 3029.2 - 1.06E+06 - - - 1.2533 - 1.386 0.224 - 180.5 1 1 0 0.001 7 0 0 0 - - - - - 1.7294 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.13919.13919.2 0.000749 16-Aug K.FTPGAVMLR.V "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 990.5321 1.6 38589 13919 2 990.535291 496.2733 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.75 3029.4 - 360814 - - - 3.2498 - 1.522 0.394 - 187.6 1 2 0 0.0032 9 0 0 0 5.32E+07 3.33E+07 - - - 3.1652 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.13920.13920.2 0.0234 18-Oct K.NLQEAEEWYK[136.11].S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1316.6128 1.87 38590 13920 2 1316.614431 659.3137 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3029.5 - 197485 - - - 1.2145 - 1.669 0.342 - 317.1 1 2 0 0.0016 10 0 0 0 2.18E+07 1.17E+07 - - - 2.9963 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.13923.13923.2 0.000689 14-Jul R.VLVLVPTR[166.11].E "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 905.5938 0.9 38591 13923 2 905.594402 453.8042 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 9.72 3029.9 - 1.58E+06 - - - 0.7111 - 1.693 0.216 - 198.1 1 2 0 0.0006 8 0 0 0 7.77E+07 8.65E+07 - - - 2.2241 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.13926.13926.2 0.00388 18-Sep R.VLAESLGPLR[166.11].E sp|Q4KMQ1|TPRN_HUMAN 1 1063.6265 1.37 38594 13926 2 1063.626822 532.8205 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 5.97 3030.2 - 1.24E+06 - - - 0.2886 - 1.739 0.259 - 258.7 1 2 0 0.0003 10 0 0 0 6.38E+07 4.67E+07 - - - 2.4983 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.13936.13936.2 0.000126 14-Sep R.VLVLVPTR.E "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 895.5855 0.9 38600 13936 2 895.586382 448.8 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 9.72 3031.4 - 1.93E+06 - - - 0.9982 - 1.774 0.347 - 286.4 1 2 0 0.0009 8 0 0 0 7.77E+07 8.65E+07 - - - 3.3325 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.13943.13943.2 0.696 14-Aug R.AQVSLLIR.R "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 898.56 1.25 38602 13943 2 898.560613 450.2873 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 9.79 3032.4 - 2.31E+06 - - - 0.68 - 1.704 0.272 - 257.9 1 2 0 0.0006 8 0 0 0 5.72E+07 4.57E+07 - - - 2.6572 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.13947.13947.2 0.0095 14-Aug R.VWAEYALK[136.11].R sp|Q6P2Q9|PRP8_HUMAN 1 986.5317 1.3 38605 13947 2 986.533343 494.2731 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3032.9 - 1.63E+06 - - - 1.6979 - 1.632 0.352 - 253.3 1 2 0 0.0017 8 0 0 0 2.82E+08 2.16E+08 - - - 3.1176 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.13951.13951.2 0.282 14-Jul R.LPLATIVK.D sp|O94776|MTA2_HUMAN 1 853.5637 1.53 38607 13951 2 853.56514 427.7891 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 3033.4 - 735320 - - - 1.6988 - 1.579 0.208 - 96.7 2 2 0 0.0014 8 0 0 0 2.69E+08 1.76E+08 - - - 1.82 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.13955.13955.2 0.0659 14-Jul R.EAVLSLYR.A sp|L0R8F8|MIDUO_HUMAN 1 949.5233 1.09 38609 13955 2 949.525376 475.7689 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 6.1 3033.8 - 1.74E+06 - - - 2.2053 - 1.549 0.194 - 131.7 1 2 0 0.0021 8 0 0 0 5.93E+07 5.44E+07 - - - 1.793 0.995 230117_WJC_METTL3_WT_vs_EV_F05.13956.13956.2 0.113 16-Jul K.FTPGAVMLR[166.11].V "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1000.5403 2 38610 13956 2 1000.5421 501.2774 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.75 3033.9 - 775394 - - - 1.7571 - 1.236 0.182 - 155.6 1 2 0 0.0018 9 0 0 0 5.13E+07 2.56E+07 - - - 0.9977 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.13973.13973.2 0.134 14-Jul K.LYLADPMK.A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 949.4943 1.53 38618 13973 2 949.494307 475.7544 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 3036 - 2.06E+06 - - - 0.0179 - 1.355 0.259 - 140.5 1 2 0 0 8 0 0 0 3.16E+08 2.06E+08 - - - 1.8702 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.13981.13981.2 0.00161 14-Sep K.LYLADPMK[136.11].A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 957.5085 1.53 38622 13981 2 957.50831 479.7615 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 3037 - 2.19E+06 - - - -0.188 - 1.736 0.382 - 240.3 1 2 0 -0.0002 8 0 0 0 3.16E+08 2.07E+08 - - - 3.5259 0.9898 230117_WJC_METTL3_WT_vs_EV_F05.13982.13982.2 1.34 12-Jun R.GLIDSLR.A sp|P53992|SC24C_HUMAN 1 772.4443 0.14 38623 13982 2 772.446095 387.2294 Protein transport protein Sec24C OS=Homo sapiens OX=9606 GN=SEC24C PE=1 SV=3 5.84 3037.1 - 405894 - - - 2.3199 - 1.288 0.105 - 114.4 1 2 0 0.0018 7 0 0 0 1.82E+07 1.34E+08 - - - 0.6179 0.9876 230117_WJC_METTL3_WT_vs_EV_F05.13988.13988.2 0.0528 14-Jul K.FVDGEWYR.A sp|Q7KZF4|SND1_HUMAN 1 1070.4821 1.31 38625 13988 2 1070.482209 536.2483 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.37 3038 - 540479 - - - 0.0598 - 0.959 0.224 - 122.2 1 2 0 0.0001 8 0 0 0 1.25E+07 9.55E+06 - - - 0.5692 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.13995.13995.2 0.0233 14-Jun R.VWAEYALK.R sp|Q6P2Q9|PRP8_HUMAN 1 978.5175 1.27 38627 13995 2 978.51801 490.266 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3039 - 6.01E+06 - - - 0.5539 - 1.416 0.344 - 132.7 1 2 0 0.0005 8 0 0 0 2.85E+08 2.25E+08 - - - 2.6307 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.13996.13996.2 0.000463 18-Sep R.VPLVAPEDLR[166.11].D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1117.6371 0.51 38628 13996 2 1117.637573 559.8258 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3039.1 - 544466 - - - 0.442 - 2.127 0.408 - 341.9 1 2 0 0.0005 10 0 0 0 8.52E+08 1.68E+09 - - - 4.161 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.13999.13999.2 13.8 12-Sep K.IISIIVK.N "sp|Q9Y4A5|TRRAP_HUMAN,sp|Q6PEY0|CXB7_HUMAN,sp|Q96QE4|LR37B_HUMAN,tr|J3QSU1|J3QSU1_HUMAN,tr|J3KTP0|J3KTP0_HUMAN,tr|A0A0A0MRM5|A0A0A0MRM5_HUMAN,tr|J3QLI7|J3QLI7_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 9 784.5422 1.35 38629 13999 2 784.543359 393.2784 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3039.5 - 814492 - - - 1.4442 - 1.988 0.044 - 201.9 1 2 0 0.0011 7 0 0 0 2.78E+07 2.06E+07 - - - 1.5428 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.14009.14009.2 0.00884 12-Aug R.VFDMLNR[166.11].R "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 12 903.4512 1.55 38634 14009 2 903.453361 452.7329 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3040.8 - 327576 - - - 2.3997 - 1.595 0.357 - 205 1 2 0 0.0022 7 0 0 0 6.99E+07 4.52E+07 - - - 3.1564 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.14012.14012.2 0.0107 12-Aug R.FTDILVR.H sp|O43143|DHX15_HUMAN 1 862.4913 1.05 38635 14012 2 862.492074 432.2529 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 3041.2 - 5.45E+06 - - - 0.9519 - 1.537 0.342 - 227.8 1 2 0 0.0008 7 0 0 0 5.45E+08 5.22E+08 - - - 2.9287 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.14029.14029.2 0.00216 20-Jun K.YFVEAGAMAVR[166.11].R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1222.6044 10.14 38646 14029 2 1222.607163 612.3095 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3043.1 - 140454 - - - 2.2607 - 1.415 0.42 - 115 1 2 0 0.0028 11 0 0 0 8.39E+08 8.28E+07 - - - 3.0813 1 230117_WJC_METTL3_WT_vs_EV_F05.14033.14033.2 0.000469 20-Dec K.YFVEAGAMAVR.R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1212.5961 10.15 38648 14033 2 1212.598669 607.3053 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3043.6 - 2.10E+06 - - - 2.0947 - 2.317 0.541 - 535 1 2 0 0.0025 11 0 0 0 8.40E+08 8.28E+07 - - - 5.3092 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.14045.14045.2 0.226 18-Nov R.VPLVAPEDLR.D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1107.6288 0.51 38654 14045 2 1107.630312 554.8217 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3045.1 - 4.06E+06 - - - 1.357 - 2.223 0.356 - 641.5 1 2 0 0.0015 10 0 0 0 8.52E+08 1.68E+09 - - - 3.8998 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.14046.14046.2 0.06 16-Aug R.VPPEFLVQR.A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1083.6077 1.55 38655 14046 2 1083.609382 542.8111 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3045.2 - 568458 - - - 1.5707 - 1.429 0.247 - 228.4 1 2 0 0.0017 9 0 0 0 7.18E+07 4.63E+07 - - - 1.8976 0.9903 230117_WJC_METTL3_WT_vs_EV_F05.14059.14059.2 0.366 12-Jul K.IAWALSR.K sp|Q04760|LGUL_HUMAN 1 815.4654 1.09 38662 14059 2 815.465451 408.74 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 9.75 3046.7 - 1.01E+06 - - - 0.0957 - 1.401 0.084 - 170 1 2 0 0.0001 7 0 0 0 1.18E+08 1.08E+08 - - - 0.7298 1 230117_WJC_METTL3_WT_vs_EV_F05.14060.14060.2 5.29E-06 26-Nov K.IFVGGLSPDTPEEK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1487.7508 1.53 38663 14060 2 1487.755164 744.8827 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3046.9 - 216030 - - - 2.9501 - 2.057 0.557 - 183.9 1 2 0 0.0044 14 0 0 0 9.28E+06 6.06E+06 - - - 4.9636 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.14065.14065.2 0.24 16-Oct K.LADMGIAIR[166.11].V sp|Q9Y3I0|RTCB_HUMAN 1 968.5353 1.26 38666 14065 2 968.537592 485.2749 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.84 3047.5 - 758173 - - - 2.4109 - 1.939 0.166 - 317.3 1 2 0 0.0023 9 0 0 0 2.74E+08 2.17E+08 - - - 2.182 1 230117_WJC_METTL3_WT_vs_EV_F05.14066.14066.2 2.75E-07 26-Oct K.IFVGGLSPDTPEEK[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1495.765 1.53 38667 14066 2 1495.76823 748.8898 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3047.6 - 247480 - - - 2.1761 - 1.887 0.57 - 178.8 1 2 0 0.0033 14 0 0 0 9.28E+06 6.06E+06 - - - 4.8435 0.9578 230117_WJC_METTL3_WT_vs_EV_F05.14068.14068.3 0.0545 Aug-68 R.VAPEEHPVLLTEAPLNPK.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1953.0571 41.53 38669 14068 3 1953.06505 652.0263 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 3047.9 - 127323 - - - 4.0562 - 1.644 0.141 - 36.6 1 2 0 0.0079 18 0 0 0 2.87E+06 6.92E+04 - - - 1.3477 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.14077.14077.2 0.00774 12-Jun R.FTDILVR[166.11].H sp|O43143|DHX15_HUMAN 1 872.4995 1.04 38674 14077 2 872.500561 437.257 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 3049 - 8.90E+06 - - - 1.1897 - 1.357 0.376 - 118.3 1 2 0 0.001 7 0 0 0 5.45E+08 5.22E+08 - - - 2.7851 0.993 230117_WJC_METTL3_WT_vs_EV_F05.14078.14078.2 0.352 12-Apr R.FLGLTER[166.11].D sp|P07099|HYEP_HUMAN 1 844.4682 1.26 38675 14078 2 844.469199 423.2414 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 6 3049.1 - 1.34E+06 - - - 1.1558 - 1.255 0.183 - 34.5 7 2 0 0.001 7 0 0 0 6.79E+07 5.41E+07 - - - 0.7345 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.14083.14083.2 0.0243 14-Jul K.AINTFFAK[136.11].N "sp|Q71RC2|LARP4_HUMAN,tr|Q96J85|Q96J85_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 3 918.5055 1.67 38678 14083 2 918.508299 460.26 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 8.8 3049.7 - 1.02E+06 - - - 3.0985 - 1.31 0.343 - 136.7 1 2 0 0.0028 8 0 0 0 4.88E+07 2.91E+07 - - - 2.3879 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.14085.14085.2 0.00324 18-Aug R.VPYVIISAAK.G "sp|P28340|DPOD1_HUMAN,tr|M0QXQ2|M0QXQ2_HUMAN,tr|M0QXE6|M0QXE6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 5 1059.6328 1.91 38680 14085 2 1059.634492 530.8237 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.56 3049.9 - 472041 - - - 1.5666 - 1.823 0.402 - 198.2 1 2 0 0.0017 10 0 0 0 9.50E+06 4.97E+06 - - - 3.6858 0.9905 230117_WJC_METTL3_WT_vs_EV_F05.14096.14096.2 0.405 12-Jul R.SLILAMK[136.11].A sp|Q7Z353|HDX_HUMAN 1 782.4815 0.5 38686 14096 2 782.482874 392.248 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 8.47 3051.3 - 1.13E+06 - - - 1.6959 - 1.447 0.043 - 208.9 1 2 0 0.0013 7 0 0 0 1.86E+07 3.69E+07 - - - 0.5289 0.9969 230117_WJC_METTL3_WT_vs_EV_F05.14097.14097.2 4.2 14-Sep K.LLGPVLVK.Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 837.5688 3.87 38687 14097 2 837.569761 419.7917 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 3051.3 - 2.24E+06 - - - 1.1772 - 1.623 0.115 - 160.8 1 2 0 0.001 8 0 0 0 1.08E+09 2.79E+08 - - - 1.3506 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.14104.14104.2 0.0811 16-Jul K.LFGETTLVK.S sp|P50748|KNTC1_HUMAN 1 1006.5699 0.82 38690 14104 2 1006.571185 504.2922 Kinetochore-associated protein 1 OS=Homo sapiens OX=9606 GN=KNTC1 PE=1 SV=1 6 3052.3 - 417601 - - - 1.2786 - 1.351 0.173 - 97.9 2 2 0 0.0013 9 0 0 0 9.74E+06 1.19E+07 - - - 1.0543 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.14110.14110.2 0.115 14-Aug R.LPLATIVK[136.11].D sp|O94776|MTA2_HUMAN 1 861.5779 1.53 38694 14110 2 861.579096 431.7962 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 3053 - 2.95E+06 - - - 1.3998 - 1.636 0.319 - 190.5 1 2 0 0.0012 8 0 0 0 2.69E+08 1.76E+08 - - - 2.8814 1 230117_WJC_METTL3_WT_vs_EV_F05.14114.14114.2 0.0069 14/22 K.SPILVATAVAAR[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1177.7058 1.12 38698 14114 2 1177.708707 589.8602 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3053.4 - 320089 - - - 2.4446 - 2.871 0.436 - 609 1 2 0 0.0029 12 0 0 0 6.84E+08 6.12E+08 - - - 5.0354 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.14127.14127.2 0.0481 18-Jun K.LFPGSPAIYK.L "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|F8W705|F8W705_HUMAN,tr|C9JF75|C9JF75_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|C9J6W1|C9J6W1_HUMAN,tr|H0YBN8|H0YBN8_HUMAN,tr|C9J1W9|C9J1W9_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 17 1091.6015 4.44 38706 14127 2 1091.603962 546.808 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 8.59 3055 - 317549 - - - 2.2261 - 1.262 0.252 - 74 2 2 0 0.0024 10 0 0 0 4.96E+07 1.12E+07 - - - 1.4166 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.14136.14136.2 0.478 14-Aug R.LLAMLEQK.N "sp|Q96EA4|SPDLY_HUMAN,tr|H0YBG5|H0YBG5_HUMAN" 2 944.5365 16.24 38710 14136 2 944.537572 473.2755 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 6 3056 - 1.05E+06 - - - 1.1466 - 1.458 0.313 - 129.1 1 2 0 0.0011 8 0 0 0 3.53E+07 2.17E+06 - - - 2.4897 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.14137.14137.2 0.0738 16-Jun K.VLPLEEAYR.F sp|Q9H223|EHD4_HUMAN 1 1088.5866 1.71 38711 14137 2 1088.590398 545.3006 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 3056.1 - 588758 - - - 3.4797 - 1.294 0.281 - 117.8 1 2 0 0.0038 9 0 0 0 2.29E+08 1.34E+08 - - - 1.8609 1 230117_WJC_METTL3_WT_vs_EV_F05.14140.14140.2 0.0017 22-Dec K.SPILVATAVAAR.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1167.6976 1.12 38712 14140 2 1167.699857 584.8561 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3056.5 - 1.48E+06 - - - 1.9688 - 2.471 0.505 - 548.6 1 2 0 0.0023 12 0 0 0 6.85E+08 6.12E+08 - - - 5.1504 0.986 230117_WJC_METTL3_WT_vs_EV_F05.14145.14145.2 4.14 14-Jul K.GIGLAIVR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 807.5206 0.94 38715 14145 2 807.521567 404.7676 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 3057.1 - 729632 - - - 1.2062 - 1.237 0.076 - 127.7 1 2 0 0.001 8 0 0 0 5.15E+08 5.48E+08 - - - 0.2435 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.14157.14157.2 0.0818 14-Aug R.VPDVVLIK.K "sp|Q96D46|NMD3_HUMAN,tr|C9JA08|C9JA08_HUMAN" 2 881.5586 2.31 38723 14157 2 881.560881 441.7866 60S ribosomal export protein NMD3 OS=Homo sapiens OX=9606 GN=NMD3 PE=1 SV=1 5.81 3058.5 - 791859 - - - 2.5818 - 1.429 0.223 - 138.3 1 2 0 0.0023 8 0 0 0 3.47E+07 1.50E+07 - - - 1.764 0.9953 230117_WJC_METTL3_WT_vs_EV_F05.14185.14185.2 0.438 14-Aug R.LLLIATGK.R "sp|Q9NQW6|ANLN_HUMAN,tr|H7C1K5|H7C1K5_HUMAN" 2 827.548 0.05 38742 14185 2 827.548726 414.7813 Anillin OS=Homo sapiens OX=9606 GN=ANLN PE=1 SV=2 8.75 3061.8 - 1.48E+06 - - - 0.829 - 1.496 0.109 - 160.8 1 2 0 0.0007 8 0 0 0 4.42E+07 9.57E+08 - - - 1.0607 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.14192.14192.2 0.0146 14-Sep K.VITMFVQR.Q "sp|P13010|XRCC5_HUMAN,tr|C9JZ81|C9JZ81_HUMAN,tr|H7C0H9|H7C0H9_HUMAN" 3 992.5477 0.87 38746 14192 2 992.547211 497.2811 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 9.72 3062.7 - 568791 - - - -0.5148 - 1.801 0.299 - 238.8 1 2 0 -0.0005 8 0 0 0 1.32E+08 1.53E+08 - - - 3.0237 0.988 230117_WJC_METTL3_WT_vs_EV_F05.14193.14193.2 0.478 16-Sep R.LAEYYGLYR[166.11].D sp|Q96DV4|RM38_HUMAN 1 1156.5792 1.16 38747 14193 2 1156.577187 579.2969 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3062.9 - 514080 - - - -1.7664 - 1.725 0.113 - 320.3 1 2 0 -0.002 9 0 0 0 5.91E+07 5.11E+07 - - - 1.4523 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.14198.14198.2 0.0509 16-Oct R.LAEYYGLYR.D sp|Q96DV4|RM38_HUMAN 1 1146.571 1.16 38750 14198 2 1146.572371 574.2928 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3063.5 - 585851 - - - 1.2306 - 2.126 0.338 - 436.4 1 2 0 0.0014 9 0 0 0 5.91E+07 5.11E+07 - - - 3.7191 0.9941 230117_WJC_METTL3_WT_vs_EV_F05.14202.14202.2 0.178 12-May K.IVQWDIR.S "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 928.5131 1.31 38752 14202 2 928.513412 465.2638 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.84 3064 - 431813 - - - 0.3888 - 1.228 0.178 - 71.8 1 2 0 0.0004 7 0 0 0 1.17E+07 8.92E+06 - - - 1.0064 0.9937 230117_WJC_METTL3_WT_vs_EV_F05.14209.14209.2 0.00832 18-Aug K.LPAVVTADLR.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1053.6182 2.19 38754 14209 2 1053.619671 527.8164 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.84 3064.9 - 119323 - - - 1.3534 - 1.596 0.061 - 158.7 1 2 0 0.0014 10 0 0 0 5.06E+07 2.32E+07 - - - 0.796 0.9928 230117_WJC_METTL3_WT_vs_EV_F05.14215.14215.2 0.413 14-Jul K.VLLSALER[166.11].L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 909.5523 2.56 38757 14215 2 909.55389 455.7834 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.97 3065.6 - 489516 - - - 1.7624 - 1.432 0.083 - 122.4 1 2 0 0.0016 8 0 0 0 5.52E+08 2.16E+08 - - - 0.7365 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.14217.14217.2 0.0832 12-Aug K.LWNGLVK.V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 828.4858 1.05 38758 14217 2 828.486818 415.2502 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 3065.8 - 1.25E+06 - - - 1.2601 - 1.386 0.342 - 136.5 1 2 0 0.001 7 0 0 0 8.93E+07 8.47E+07 - - - 2.601 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.14218.14218.2 0.0157 16-Oct R.VLGVLEVSR.S "sp|Q9H0C8|ILKAP_HUMAN,tr|F8SNU7|F8SNU7_HUMAN,tr|H7C2I8|H7C2I8_HUMAN" 3 970.5811 3.58 38759 14218 2 970.582581 486.2978 Integrin-linked kinase-associated serine\threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1 5.97 3065.9 - 605355 - - - 1.494 - 1.712 0.372 - 260.7 1 2 0 0.0014 9 0 0 0 4.17E+07 1.17E+07 - - - 3.3436 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.14225.14225.2 0.0207 12-Jul K.LWNGLVK[136.11].V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 836.5 1.05 38762 14225 2 836.501526 419.2573 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 3066.8 - 2.65E+06 - - - 1.8553 - 1.498 0.335 - 96.7 1 2 0 0.0016 7 0 0 0 8.91E+07 8.47E+07 - - - 2.7953 0.9925 230117_WJC_METTL3_WT_vs_EV_F05.14233.14233.2 4 12-Jul K.ALDLLDR.M "sp|P27361|MK03_HUMAN,sp|Q99759|M3K3_HUMAN,tr|H0YEX6|H0YEX6_HUMAN,tr|J3KRN4|J3KRN4_HUMAN,tr|J3QRB6|J3QRB6_HUMAN,tr|B3KR49|B3KR49_HUMAN,tr|E9PQW4|E9PQW4_HUMAN,tr|E9PRH7|E9PRH7_HUMAN,tr|E9PBK7|E9PBK7_HUMAN" 9 814.4549 0.82 38766 14233 2 814.456359 408.2347 Mitogen-activated protein kinase 3 OS=Homo sapiens OX=9606 GN=MAPK3 PE=1 SV=4 4.21 3067.9 - 921337 - - - 1.8307 - 1.469 0.062 - 146.9 1 2 0 0.0015 7 0 0 0 3.15E+07 3.86E+07 - - - 0.717 0.89 230117_WJC_METTL3_WT_vs_EV_F05.14235.14235.2 0.298 12-Sep S.VGAEIQR.L tr|D6RFZ9|D6RFZ9_HUMAN 1 771.4239 1.14 38767 14235 2 771.425237 386.7192 Receptor of-activated protein C kinase 1 (Fragment) OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=8 5.97 3068.1 - 392458 - - - 1.7306 - 1.532 0.215 - 231.7 1 1 0 0.0013 7 0 0 0 1.88E+07 1.64E+07 - - - 1.9802 0.9249 230117_WJC_METTL3_WT_vs_EV_F05.14239.14239.2 2.98 14-May K.DGETIELR.L "sp|P20062|TCO2_HUMAN,tr|B5MBX2|B5MBX2_HUMAN,tr|F8WE86|F8WE86_HUMAN" 3 931.4611 3.59 38769 14239 2 931.464054 466.7378 Transcobalamin-2 OS=Homo sapiens OX=9606 GN=TCN2 PE=1 SV=3 4.14 3068.6 - 330714 - - - 3.1982 - 1.159 0.032 - 76.6 2 2 0 0.003 8 0 0 0 2.67E+07 7.45E+06 - - - -0.413 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.14245.14245.2 0.377 20-Sep K.DAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1160.5561 42.55 38772 14245 2 1160.560408 581.2853 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.92 3069.4 - 244116 - - - 3.7137 - 2.089 0.423 - 191.6 1 2 0 0.0043 11 0 0 0 8.20E+06 1.93E+05 - - - 4.1568 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.14247.14247.2 0.000961 16-Aug K.LLVLDPAQR.L sp|P50750|CDK9_HUMAN 1 1023.6077 1.89 38774 14247 2 1023.610737 512.8111 Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3 5.84 3069.6 - 356757 - - - 2.9865 - 1.738 0.37 - 201.6 1 2 0 0.0031 9 0 0 0 4.60E+07 2.44E+07 - - - 3.372 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.14261.14261.2 0.0711 14-Jun K.VLLSALER.L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 899.544 2.25 38781 14261 2 899.54572 450.7793 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.97 3071.5 - 1.24E+07 - - - 1.8932 - 1.495 0.28 - 111.3 1 2 0 0.0017 8 0 0 0 5.55E+08 2.47E+08 - - - 2.3213 0.993 230117_WJC_METTL3_WT_vs_EV_F05.14271.14271.2 0.197 14-Jun K.VLETFLAK.S "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 919.5379 1.45 38789 14271 2 919.540161 460.7762 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 5.97 3072.6 - 1.46E+06 - - - 2.4926 - 1.297 0.154 - 109.1 1 2 0 0.0023 8 0 0 0 8.11E+07 5.60E+07 - - - 0.962 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.14274.14274.2 0.0145 16-Nov K.LNSLAIGLR.Q sp|P54886|P5CS_HUMAN 1 955.5815 1.53 38792 14274 2 955.584768 478.798 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3073 - 443647 - - - 3.4565 - 2.2 0.352 - 326.6 1 2 0 0.0033 9 0 0 0 6.51E+07 4.26E+07 - - - 3.9209 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.14283.14283.2 0.0288 16-Oct K.LNSLAIGLR[166.11].Q sp|P54886|P5CS_HUMAN 1 965.5897 1.6 38797 14283 2 965.592953 483.8021 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3074.1 - 572732 - - - 3.3327 - 2.335 0.361 - 323.6 1 2 0 0.0032 9 0 0 0 6.89E+07 4.31E+07 - - - 4.1597 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.14291.14291.2 0.107 12-Aug K.LSAFAFK.Q sp|O75717|WDHD1_HUMAN 1 782.4327 1.82 38803 14291 2 782.434099 392.2236 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 8.75 3075.2 - 712169 - - - 1.8187 - 1.537 0.223 - 160.2 1 2 0 0.0014 7 0 0 0 3.45E+07 1.89E+07 - - - 2.0496 0.8941 230117_WJC_METTL3_WT_vs_EV_F05.14306.14306.2 2.14 12-Jun R.GIITLYR.H "sp|O14981|BTAF1_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 2 834.4963 4.51 38811 14306 2 834.500089 418.2554 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 8.75 3077.1 - 474669 - - - 4.4937 - 1.006 0.132 - 79.2 2 2 0 0.0037 7 0 0 0 9.28E+07 2.06E+07 - - - -0.1007 0.874 230117_WJC_METTL3_WT_vs_EV_F05.14308.14308.2 0.00427 12-Aug D.GDFVVLK.R sp|Q9UJA5|TRM6_HUMAN 1 776.4432 1.06 38812 14308 2 776.445656 389.2289 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 OS=Homo sapiens OX=9606 GN=TRMT6 PE=1 SV=1 5.84 3077.3 - 264086 - - - 3.1116 - 1.509 0.288 - 241 1 1 0 0.0024 7 0 0 0 1.60E+07 1.51E+07 - - - 2.4711 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.14309.14309.2 0.000121 28-Sep R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 0.16 38813 14309 2 1410.786421 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3077.4 - 118959 - - - 2.3696 - 1.821 0.401 - 146 1 2 0 0.0033 15 0 0 0 9.53E+06 6.02E+07 - - - 3.4754 0.9889 230117_WJC_METTL3_WT_vs_EV_F05.14323.14323.2 0.0361 18-Jul K.IMLVEPPVAK[136.11].V sp|P18583|SON_HUMAN 1 1103.6504 1.55 38819 14323 2 1103.654238 552.8325 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3079.2 - 297562 - - - 3.4748 - 1.458 0.13 - 88.2 1 2 0 0.0038 10 0 0 0 7.37E+07 4.76E+07 - - - 1.0525 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.14331.14331.2 0.0358 12-Jul R.FLDPEFR.E sp|Q5VUA4|ZN318_HUMAN 1 922.4549 1.69 38823 14331 2 922.456287 462.2347 Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2 4.37 3080.3 - 1.37E+06 - - - 1.5383 - 1.367 0.309 - 179 1 2 0 0.0014 7 0 0 0 5.63E+07 3.33E+07 - - - 2.3134 1 230117_WJC_METTL3_WT_vs_EV_F05.14343.14343.2 0.000642 18-Oct R.IATANMLGIR.K sp|Q9NX20|RM16_HUMAN 1 1058.5907 1 38831 14343 2 1058.594567 530.3026 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3081.8 - 427551 - - - 3.7002 - 2.341 0.466 - 265.5 1 2 0 0.0039 10 0 0 0 5.81E+07 5.83E+07 - - - 4.8559 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.14349.14349.2 0.00175 18-Dec R.IATANMLGIR[166.11].K sp|Q9NX20|RM16_HUMAN 1 1068.5989 1.1 38834 14349 2 1068.601739 535.3067 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3082.6 - 583177 - - - 2.638 - 1.936 0.34 - 483.5 1 2 0 0.0028 10 0 0 0 5.79E+07 5.24E+07 - - - 3.3954 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.14355.14355.2 0.00458 14-Jul K.LITEDFVR.Q sp|Q96MG7|NSE3_HUMAN 1 991.5338 11.11 38836 14355 2 991.53694 496.7742 Non-structural maintenance of chromosomes element 3 homolog OS=Homo sapiens OX=9606 GN=NSMCE3 PE=1 SV=1 4.37 3083.4 - 606801 - - - 3.1204 - 1.544 0.412 - 141.2 1 2 0 0.0031 8 0 0 0 2.16E+07 1.94E+06 - - - 3.3931 0.9946 230117_WJC_METTL3_WT_vs_EV_F05.14356.14356.2 0.00176 26-Sep K.VPQVSTPTLVEVSR.N "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1510.8355 999 38837 14356 2 1510.845038 756.425 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.97 3083.5 - 80207.9 - - - 6.3078 - 1.936 0.443 - 258.4 1 2 0 0.0095 14 0 0 0 2.30E+06 0.00E+00 - - - 3.9678 0.9952 230117_WJC_METTL3_WT_vs_EV_F05.14361.14361.2 0.0841 22-Sep K.SPILVATAVAAR[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1177.7058 1.12 38841 14361 2 1177.709224 589.8602 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3084.1 - 100282 - - - 2.8836 - 1.891 0.097 - 222.7 1 2 0 0.0034 12 0 0 0 6.85E+08 6.12E+08 - - - 1.4327 0.9833 230117_WJC_METTL3_WT_vs_EV_F05.14368.14368.2 1.06 12-Jun R.FLTFAER[166.11].L sp|O75691|UTP20_HUMAN 1 892.4682 1.19 38845 14368 2 892.470916 447.2414 Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3 6 3084.9 - 613168 - - - 3.0175 - 1.237 0.13 - 111.1 2 2 0 0.0027 7 0 0 0 2.85E+07 2.39E+07 - - - 0.5398 0.9918 230117_WJC_METTL3_WT_vs_EV_F05.14375.14375.2 254 12-May K.RIYGGFK[136.11].S sp|Q14520|HABP2_HUMAN 1 847.4796 - 38850 14375 2 847.480569 424.7471 Hyaluronan-binding protein 2 OS=Homo sapiens OX=9606 GN=HABP2 PE=1 SV=1 9.99 3085.8 - 1.14E+06 - - - 1.1752 - 1.226 0.154 - 58.5 3 2 0 0.001 7 0 0 0 - - - - - 0.6106 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.14380.14380.2 0.0389 14-Aug K.VPGIFISR[166.11].M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 897.5312 0.04 38853 14380 2 897.533078 449.7729 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3086.4 - 1.07E+06 - - - 2.1392 - 1.578 0.297 - 211.6 1 2 0 0.0019 8 0 0 0 1.94E+07 4.94E+08 - - - 2.6098 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.14381.14381.2 0.000113 18-Jul K.LFPGSPAIYK.L "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|F8W705|F8W705_HUMAN,tr|C9JF75|C9JF75_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|C9J6W1|C9J6W1_HUMAN,tr|H0YBN8|H0YBN8_HUMAN,tr|C9J1W9|C9J1W9_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 17 1091.6015 1.82 38854 14381 2 1091.603871 546.808 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 8.59 3086.6 - 341381 - - - 2.1427 - 1.454 0.416 - 134.6 1 2 0 0.0023 10 0 0 0 3.93E+07 2.16E+07 - - - 3.1577 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.14388.14388.2 0.842 12-Jul K.GADVWFK.E sp|P05109|S10A8_HUMAN 1 821.4072 6.41 38857 14388 2 821.407551 411.7109 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 5.84 3087.5 - 717221 - - - 0.4407 - 1.592 0.191 - 195.7 1 2 0 0.0004 7 0 0 0 2.48E+07 3.87E+06 - - - 1.925 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.14390.14390.2 0.123 14-Sep K.VPGIFISR.M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 887.5229 0.27 38859 14390 2 887.524317 444.7687 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3087.7 - 1.83E+06 - - - 1.6101 - 1.592 0.154 - 278.7 1 2 0 0.0014 8 0 0 0 1.00E+08 3.76E+08 - - - 1.5804 0.993 230117_WJC_METTL3_WT_vs_EV_F05.14391.14391.2 0.256 12-Jul R.FWETLDR[166.11].Y "sp|Q6P1J9|CDC73_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN" 2 975.469 1.77 38860 14391 2 975.471848 488.7418 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 4.37 3087.8 - 592084 - - - 2.9699 - 1.305 0.173 - 167 1 2 0 0.0029 7 0 0 0 4.12E+07 2.33E+07 - - - 1.1613 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.14392.14392.2 0.135 16-Aug R.FLAEEGFYK[136.11].F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1110.5477 1.3 38861 14392 2 1110.549633 556.2811 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3087.9 - 289753 - - - 1.7298 - 1.476 0.337 - 167.4 1 2 0 0.0019 9 0 0 0 1.15E+08 8.85E+07 - - - 2.6558 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.14396.14396.2 0.209 12-Aug K.LPNLLGR[166.11].A sp|Q9Y512|SAM50_HUMAN 1 791.4893 0.92 38863 14396 2 791.491034 396.7519 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 9.75 3088.4 - 558151 - - - 2.1997 - 1.599 0.232 - 179.2 1 2 0 0.0017 7 0 0 0 1.05E+07 1.15E+07 - - - 2.2413 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.14397.14397.2 9.91E-05 16-Sep R.FLAEEGFYK.F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1102.5335 1.3 38864 14397 2 1102.536856 552.274 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3088.5 - 340255 - - - 3.033 - 1.605 0.492 - 223 1 2 0 0.0033 9 0 0 0 1.15E+08 8.85E+07 - - - 4.0426 0.9542 230117_WJC_METTL3_WT_vs_EV_F05.14399.14399.2 1.1 18-May R.SLVVPAYAYR.K sp|Q9Y3R4|NEUR2_HUMAN 1 1137.6182 125.49 38866 14399 2 1137.619877 569.8164 Sialidase-2 OS=Homo sapiens OX=9606 GN=NEU2 PE=1 SV=2 8.31 3088.8 - 129813 - - - 1.4346 - 1.267 0.004 - 54.2 4 2 0 0.0016 10 0 0 0 3.43E+06 2.73E+04 - - - -0.5383 0.9963 230117_WJC_METTL3_WT_vs_EV_F05.14403.14403.2 0.167 14-Aug R.IGFIEEVK.A sp|Q96P63|SPB12_HUMAN 1 933.5171 35.56 38869 14403 2 933.518934 467.7658 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 4.53 3089.1 - 3.26E+06 - - - 1.9282 - 1.345 0.181 - 144.6 1 2 0 0.0018 8 0 0 0 1.66E+08 4.66E+06 - - - 1.2712 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.14414.14414.2 0.00428 16-Aug K.TLAIELAPR[166.11].N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 992.5894 1.04 38876 14414 2 992.590609 497.302 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3090.5 - 597890 - - - 1.217 - 1.63 0.383 - 260.1 1 2 0 0.0012 9 0 0 0 1.82E+09 1.75E+09 - - - 3.2829 0.8874 230117_WJC_METTL3_WT_vs_EV_F05.14415.14415.2 0.224 14-Aug M.PTPVILLK.E "sp|Q99832|TCPH_HUMAN,tr|A0A0D9SG95|A0A0D9SG95_HUMAN,tr|F8WBP8|F8WBP8_HUMAN" 3 879.5793 12.43 38877 14415 2 879.581275 440.7969 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 9.18 3090.6 - 512967 - - - 2.1999 - 1.197 0.34 - 171.4 1 1 0 0.0019 8 0 0 0 1.79E+08 1.44E+07 - - - 2.094 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.14419.14419.2 0.0651 12-Sep R.IAAYLFK.G "sp|Q00610|CLH1_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|J3KRF5|J3KRF5_HUMAN" 5 824.4796 1.12 38879 14419 2 824.481374 413.2471 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.59 3091.2 - 2.37E+06 - - - 2.1201 - 1.682 0.232 - 235.2 1 2 0 0.0017 7 0 0 0 3.87E+08 3.45E+08 - - - 2.4016 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.14420.14420.2 0.0333 14-Aug K.QFFVAVER[166.11].E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1004.5319 0.94 38880 14420 2 1004.532225 503.2732 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 6 3091.3 - 662092 - - - 0.3375 - 1.386 0.317 - 229.6 1 2 0 0.0003 8 0 0 0 6.61E+07 7.07E+07 - - - 2.3667 0.9873 230117_WJC_METTL3_WT_vs_EV_F05.14421.14421.2 12.3 12-Jul R.VVVDLLK.L "sp|O95714|HERC2_HUMAN,tr|A0A3B3IRP6|A0A3B3IRP6_HUMAN,tr|A0A0J9YVP0|A0A0J9YVP0_HUMAN" 3 784.5058 1.09 38881 14421 2 784.507812 393.2602 E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens OX=9606 GN=HERC2 PE=1 SV=2 5.81 3091.4 - 794715 - - - 2.5124 - 1.366 0.068 - 112.7 1 2 0 0.002 7 0 0 0 7.11E+06 6.49E+06 - - - 0.5309 0.994 230117_WJC_METTL3_WT_vs_EV_F05.14425.14425.2 0.00498 20-Jul K.LIPGPLSPVAR[166.11].G sp|P48634|PRC2A_HUMAN 1 1128.6894 1.24 38885 14425 2 1128.696073 565.352 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3091.9 - 223811 - - - 5.8688 - 1.641 0.393 - 122.8 1 2 0 0.0066 11 0 0 0 6.28E+08 5.08E+08 - - - 3.2815 0.9673 230117_WJC_METTL3_WT_vs_EV_F05.14426.14426.2 0.00313 18-Sep K.WTLLQEQGTK.T "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1202.6295 18.5 38886 14426 2 1202.636771 602.322 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6 3092.1 - 185694 - - - 6.0143 - 1.761 0.127 - 173.3 1 2 0 0.0072 10 0 0 0 2.70E+06 1.46E+05 - - - 1.5563 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.14427.14427.2 0.00105 18-Aug K.FMQASEDLLK[136.11].E "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 1188.594 5.59 38887 14427 2 1188.596897 595.3043 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.37 3092.2 - 168876 - - - 2.4289 - 1.529 0.481 - 167.5 1 2 0 0.0029 10 0 0 0 2.70E+07 4.83E+06 - - - 3.778 0.9634 230117_WJC_METTL3_WT_vs_EV_F05.14428.14428.2 1.59 20-Aug M.VPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1175.7278 2.57 38888 14428 2 1175.731138 588.8712 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.72 3092.3 - 114628 - - - 2.8433 - 1.177 0.061 - 121.4 1 2 0 0.0033 11 0 0 0 1.41E+07 5.47E+06 - - - -0.0686 0.9948 230117_WJC_METTL3_WT_vs_EV_F05.14447.14447.2 0.147 18-May K.FMQASEDLLK.E "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 1180.5798 5.44 38901 14447 2 1180.58251 591.2972 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.37 3094.7 - 186540 - - - 2.287 - 1.146 0.257 - 65.3 3 2 0 0.0027 10 0 0 0 2.74E+07 5.04E+06 - - - 1.1056 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.14458.14458.2 0.000264 20-Aug K.LIPGPLSPVAR.G sp|P48634|PRC2A_HUMAN 1 1118.6812 1.24 38907 14458 2 1118.68241 560.3479 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3096.1 - 1.24E+06 - - - 1.1004 - 1.702 0.463 - 271.1 1 2 0 0.0012 11 0 0 0 6.28E+08 5.08E+08 - - - 3.899 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.14462.14462.2 0.0741 14-Aug R.ELVITIAR.E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 913.5597 1.25 38909 14462 2 913.560692 457.7871 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3096.6 - 1.32E+06 - - - 1.122 - 1.697 0.095 - 267.7 1 2 0 0.001 8 0 0 0 3.10E+08 2.48E+08 - - - 1.3374 0.9874 230117_WJC_METTL3_WT_vs_EV_F05.14463.14463.2 0.305 16-Jul K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 2.13 38910 14463 2 1014.53651 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3096.7 - 494235 - - - 1.9073 - 1.452 0.062 - 78.9 3 2 0 0.0019 9 0 0 0 1.81E+07 8.50E+06 - - - 0.3641 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.14465.14465.2 0.0259 20-Aug K.ILATTPSAVFR.V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1174.671 2.18 38912 14465 2 1174.672333 588.3428 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3096.9 - 266812 - - - 1.1271 - 1.529 0.246 - 166.7 1 2 0 0.0013 11 0 0 0 7.60E+07 3.49E+07 - - - 2.0062 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.14468.14468.2 0.00179 14-Sep K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 0.97 38913 14468 2 895.482048 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3097.3 - 857583 - - - 1.8917 - 1.484 0.434 - 219.6 1 2 0 0.0017 8 0 0 0 6.40E+07 6.57E+07 - - - 3.4365 0.9868 230117_WJC_METTL3_WT_vs_EV_F05.14470.14470.2 0.991 12-Jun R.FPYYLSR.H sp|Q8NAF0|ZN579_HUMAN 1 944.4756 1.02 38915 14470 2 944.478159 473.2451 Zinc finger protein 579 OS=Homo sapiens OX=9606 GN=ZNF579 PE=1 SV=2 8.59 3097.6 - 464891 - - - 2.7063 - 1.231 0.119 - 74.8 1 2 0 0.0026 7 0 0 0 3.39E+07 3.32E+07 - - - 0.5776 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.14471.14471.2 0.0114 16-Aug R.IIPEITAMK.A sp|Q02880|TOP2B_HUMAN 1 1014.5784 3.25 38916 14471 2 1014.578468 508.2965 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 6 3097.7 - 464880 - - - 0.1124 - 1.546 0.291 - 131.7 1 2 0 0.0001 9 0 0 0 2.29E+07 7.05E+06 - - - 2.4507 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.14474.14474.2 0.0459 14-Aug R.ELVITIAR[166.11].E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 923.5679 1.25 38917 14474 2 923.568549 462.7912 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3098.1 - 2.52E+06 - - - 0.6626 - 1.458 0.225 - 313.6 1 2 0 0.0006 8 0 0 0 3.10E+08 2.48E+08 - - - 1.8399 0.9923 230117_WJC_METTL3_WT_vs_EV_F05.14476.14476.2 1.91 14-Aug R.LLPLDFGR[166.11].Y sp|Q9UP52|TFR2_HUMAN 1 939.5417 0.03 38918 14476 2 939.543934 470.7781 Transferrin receptor protein 2 OS=Homo sapiens OX=9606 GN=TFR2 PE=1 SV=1 5.84 3098.3 - 240727 - - - 2.3543 - 1.422 0.099 - 118.5 1 2 0 0.0022 8 0 0 0 5.67E+05 1.89E+07 - - - 0.8333 0.9954 230117_WJC_METTL3_WT_vs_EV_F05.14480.14480.2 0.333 20-Aug K.ILATTPSAVFR[166.11].V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1184.6793 2.18 38919 14480 2 1184.684159 593.3469 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3098.9 - 212221 - - - 4.1193 - 1.48 0.284 - 152.9 1 2 0 0.0049 11 0 0 0 7.60E+07 3.49E+07 - - - 2.1977 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.14496.14496.2 0.718 14-Aug R.GLVGEIIK.R "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 827.5117 1 38928 14496 2 827.511806 414.7631 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6 3100.8 - 1.43E+07 - - - 0.1837 - 1.493 0.196 - 221.3 1 2 0 0.0002 8 0 0 0 5.43E+09 5.44E+09 - - - 1.6974 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.14498.14498.2 0.000625 18-Sep K.IMLVEPPVAK.V sp|P18583|SON_HUMAN 1 1095.6362 1.55 38929 14498 2 1095.636514 548.8254 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3101 - 875289 - - - 0.2839 - 1.978 0.352 - 246.8 1 2 0 0.0003 10 0 0 0 7.37E+07 4.76E+07 - - - 3.5447 0.8508 230117_WJC_METTL3_WT_vs_EV_F05.14499.14499.2 0.846 12-Jun K.ELLPEIR.E "sp|P49321|NASP_HUMAN,tr|H0YDS9|H0YDS9_HUMAN,tr|Q5T624|Q5T624_HUMAN,tr|H0YF33|H0YF33_HUMAN,tr|E9PRH9|E9PRH9_HUMAN" 5 868.5018 3 38930 14499 2 868.499615 435.2582 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 4.53 3101.2 - 823673 - - - -2.5366 - 1.284 0.008 - 146.9 1 2 0 -0.0022 7 0 0 0 8.69E+07 2.90E+07 - - - -0.1085 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.14500.14500.2 0.616 18-Nov K.AIITALGVER.R sp|Q92616|GCN1_HUMAN 1 1041.6182 1.72 38931 14500 2 1041.619261 521.8164 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 6.05 3101.3 - 1.84E+06 - - - 0.9754 - 2.213 0.242 - 394 1 2 0 0.001 10 0 0 0 7.96E+07 4.64E+07 - - - 3.0454 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.14519.14519.2 0.00381 12-Aug K.VDFVIPK.E "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 816.4745 0.27 38940 14519 2 816.473623 409.2445 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.81 3103.7 - 2.37E+06 - - - -1.1243 - 1.799 0.293 - 257.6 1 2 0 -0.0009 7 0 0 0 1.17E+08 4.34E+08 - - - 3.0655 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.14525.14525.2 0.0329 16-Aug R.VLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 969.5859 1.46 38943 14525 2 969.584985 485.8002 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3104.5 - 4.65E+06 - - - -0.9251 - 1.797 0.296 - 187.4 1 2 0 -0.0009 9 0 0 0 9.02E+08 6.20E+08 - - - 2.9226 0.9295 230117_WJC_METTL3_WT_vs_EV_F05.14531.14531.2 1.12 12-Jun R.LMDLLQK.K sp|Q9UJV9|DDX41_HUMAN 1 859.4837 0.95 38947 14531 2 859.483894 430.7491 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.84 3105.3 - 706228 - - - 0.1966 - 1.15 0.001 - 70.5 2 2 0 0.0002 7 0 0 0 8.08E+07 8.50E+07 - - - -0.6433 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.14534.14534.2 2.03E-05 16-Nov R.GSPLLIGVR.S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 910.56 1.59 38948 14534 2 910.559466 456.2873 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3105.6 - 6.28E+06 - - - -0.5886 - 1.794 0.405 - 525.1 1 2 0 -0.0005 9 0 0 0 2.49E+08 1.56E+08 - - - 3.723 0.987 230117_WJC_METTL3_WT_vs_EV_F05.14537.14537.2 0.588 12-May R.IFFVSAK.E "sp|O95140|MFN2_HUMAN,sp|Q8IWA4|MFN1_HUMAN,tr|A0A6Q8PGV8|A0A6Q8PGV8_HUMAN,tr|H7C5H5|H7C5H5_HUMAN,tr|A0A6Q8PFJ4|A0A6Q8PFJ4_HUMAN,tr|A0A6Q8PGA3|A0A6Q8PGA3_HUMAN,tr|A0A6Q8PGS9|A0A6Q8PGS9_HUMAN" 7 810.464 0.54 38951 14537 2 810.462266 406.2393 Mitofusin-2 OS=Homo sapiens OX=9606 GN=MFN2 PE=1 SV=3 8.75 3106 - 1.22E+06 - - - -2.1099 - 1.339 0.217 - 78.9 1 2 0 -0.0017 7 0 0 0 2.09E+07 3.88E+07 - - - 1.5682 0.9778 230117_WJC_METTL3_WT_vs_EV_F05.14541.14541.2 0.999 12-Jul R.TLDTFLR[166.11].S sp|Q96SK2|TM209_HUMAN 1 874.4788 1.84 38952 14541 2 874.480055 438.2467 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 5.5 3106.5 - 1.05E+06 - - - 1.4489 - 1.11 0.076 - 148.5 1 2 0 0.0013 7 0 0 0 8.99E+07 4.90E+07 - - - -0.0674 0.9815 230117_WJC_METTL3_WT_vs_EV_F05.14546.14546.2 1.7 14-Sep R.YADLLLEK.E sp|Q99459|CDC5L_HUMAN 1 963.5277 1.15 38955 14546 2 963.528713 482.7711 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3107.1 - 1.33E+06 - - - 1.0534 - 1.212 0.06 - 157 1 2 0 0.001 8 0 0 0 3.73E+08 3.25E+08 - - - 0.0637 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.14547.14547.2 0.0779 16-Oct R.GSPLLIGVR[166.11].S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 920.5683 1.59 38956 14547 2 920.567941 461.2914 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3107.2 - 4.44E+06 - - - -0.3596 - 2.067 0.401 - 454.4 1 2 0 -0.0003 9 0 0 0 2.48E+08 1.56E+08 - - - 4.1033 0.9904 230117_WJC_METTL3_WT_vs_EV_F05.14551.14551.2 1.92 14-Aug R.YADLLLEK[136.11].E sp|Q99459|CDC5L_HUMAN 1 971.5419 1.15 38958 14551 2 971.542443 486.7782 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3107.7 - 1.91E+06 - - - 0.561 - 1.456 0.075 - 115.2 2 2 0 0.0005 8 0 0 0 3.73E+08 3.25E+08 - - - 0.5934 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.14552.14552.2 0.0353 16-Oct K.FVGNIYTLK[136.11].C "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1061.6001 1.93 38959 14552 2 1061.603079 531.8073 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3107.8 - 1.08E+06 - - - 2.8231 - 1.609 0.411 - 255.8 1 2 0 0.003 9 0 0 0 1.38E+08 7.13E+07 - - - 3.4517 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.14553.14553.2 0.0958 12-Aug R.TLDTFLR.S sp|Q96SK2|TM209_HUMAN 1 864.4705 1.46 38960 14553 2 864.470031 433.2425 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 5.5 3107.9 - 2.42E+06 - - - -0.5634 - 1.553 0.278 - 214.9 1 2 0 -0.0005 7 0 0 0 9.28E+07 6.34E+07 - - - 2.4889 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.14555.14555.2 0.0513 14-May R.EFADFEYR[166.11].K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1085.4693 1.2 38962 14555 2 1085.469929 543.7419 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3108.1 - 0 - - - 0.538 - 1.229 0.321 - 113.6 1 2 0 0.0006 8 0 0 0 1.85E+07 1.54E+07 - - - 2.0336 0.9912 230117_WJC_METTL3_WT_vs_EV_F05.14557.14557.2 5.86 14-Jun R.GLVGEIIK[136.11].R "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 835.5259 1 38963 14557 2 835.525073 418.7702 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6 3108.4 - 1.49E+08 - - - -0.9347 - 1.237 0.215 - 103.4 1 2 0 -0.0008 8 0 0 0 5.43E+09 5.44E+09 - - - 1.2702 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.14559.14559.2 0.0192 16-Aug K.FVGNIYTLK.C "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1053.5859 1.93 38964 14559 2 1053.585907 527.8002 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3108.6 - 1.91E+06 - - - 0.0237 - 1.23 0.352 - 149.5 1 2 0 0 9 0 0 0 1.38E+08 7.13E+07 - - - 2.2398 0.995 230117_WJC_METTL3_WT_vs_EV_F05.14561.14561.2 7.64 12-Jun R.ELLEIVK[136.11].K sp|P31153|METK2_HUMAN 1 850.5255 1.26 38966 14561 2 850.525324 426.27 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 4.53 3108.8 - 1.50E+06 - - - -0.2304 - 1.507 0.141 - 126.9 1 2 0 -0.0002 7 0 0 0 8.09E+07 6.45E+07 - - - 1.3819 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.14569.14569.2 0.000368 16-Sep R.MGPNIYELR.T "sp|Q9BPW8|NIPS1_HUMAN,tr|C9JDV8|C9JDV8_HUMAN,tr|H7C2U6|H7C2U6_HUMAN" 3 1091.5434 1.52 38971 14569 2 1091.543667 546.779 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.75 3109.7 - 692511 - - - 0.2767 - 1.959 0.414 - 366.5 1 2 0 0.0003 9 0 0 0 6.08E+07 4.00E+07 - - - 4.0441 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.14576.14576.2 0.387 16-Nov K.TLAIELAPR.N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 982.5811 1.04 38974 14576 2 982.58141 492.2978 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3110.7 - 2.51E+06 - - - 0.2839 - 2.273 0.217 - 420.3 1 2 0 0.0003 9 0 0 0 1.82E+09 1.75E+09 - - - 3.0192 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.14577.14577.2 8.41E-05 16-Sep R.MGPNIYELR[166.11].T "sp|Q9BPW8|NIPS1_HUMAN,tr|C9JDV8|C9JDV8_HUMAN,tr|H7C2U6|H7C2U6_HUMAN" 3 1101.5516 1.52 38975 14577 2 1101.552306 551.7831 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.75 3110.8 - 461340 - - - 0.6091 - 1.805 0.489 - 290.2 1 2 0 0.0007 9 0 0 0 6.07E+07 4.00E+07 - - - 4.3611 0.955 230117_WJC_METTL3_WT_vs_EV_F05.14583.14583.2 0.144 16-Jul K.LVTEPLVLK[136.11].S sp|O43896|KIF1C_HUMAN 1 1018.6518 0.96 38979 14583 2 1018.659071 510.3332 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 6 3111.6 - 815232 - - - 7.1546 - 1.585 0.206 - 123.7 1 2 0 0.0073 9 0 0 0 3.48E+07 3.64E+07 - - - 1.8927 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.14584.14584.2 0.000451 14-Jun R.EFADFEYR.K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1075.4611 1.2 38980 14584 2 1075.461531 538.7378 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3111.8 - 671881 - - - 0.424 - 1.556 0.471 - 189.5 1 2 0 0.0005 8 0 0 0 1.85E+07 1.54E+07 - - - 3.8531 0.9931 230117_WJC_METTL3_WT_vs_EV_F05.14589.14589.2 0.484 14-Jun K.FYGELALK.K "sp|P78527|PRKDC_HUMAN,tr|F5GX40|F5GX40_HUMAN" 2 939.5066 1.15 38982 14589 2 939.507284 470.7606 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 3112.4 - 505223 - - - 0.761 - 1.156 0.178 - 87.5 1 2 0 0.0007 8 0 0 0 4.53E+07 3.95E+07 - - - 0.7927 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.14619.14619.2 0.0133 16-Aug K.LVTEPLVLK.S sp|O43896|KIF1C_HUMAN 1 1010.6376 0.81 38999 14619 2 1010.639365 506.3261 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 6 3116 - 2.00E+06 - - - 1.7632 - 1.422 0.363 - 132.6 1 2 0 0.0018 9 0 0 0 3.48E+07 4.32E+07 - - - 2.7401 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.14621.14621.2 0.00333 18-Oct R.VVVDALSGLK[136.11].G "sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|F8WCN3|F8WCN3_HUMAN" 3 1007.6106 1.82 39001 14621 2 1007.61273 504.8126 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 5.81 3116.2 - 2.04E+06 - - - 2.0673 - 2.109 0.376 - 299.8 1 2 0 0.0021 10 0 0 0 6.99E+07 3.85E+07 - - - 3.9004 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.14625.14625.2 0.0732 14-Aug K.IIYIAPMR.S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 975.5576 1.37 39003 14625 2 975.558909 488.7861 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 3116.7 - 2.83E+06 - - - 1.3838 - 1.553 0.285 - 197.2 1 2 0 0.0014 8 0 0 0 1.02E+08 7.42E+07 - - - 2.4732 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.14636.14636.2 0.0155 12-Aug R.TMLLLSR.S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 832.4841 2.22 39012 14636 2 832.48453 417.2493 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.41 3117.9 - 5.01E+06 - - - 0.5658 - 1.583 0.297 - 329.9 1 2 0 0.0005 7 0 0 0 9.44E+07 4.25E+07 - - - 2.6899 0.9928 230117_WJC_METTL3_WT_vs_EV_F05.14637.14637.2 0.49 12-May R.TMLLLSR[166.11].S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 842.4923 2.25 39013 14637 2 842.491578 422.2534 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.41 3117.9 - 2.38E+06 - - - -0.8914 - 1.174 0.253 - 92 1 2 0 -0.0008 7 0 0 0 9.31E+07 4.13E+07 - - - 1.4177 0.997 230117_WJC_METTL3_WT_vs_EV_F05.14638.14638.2 0.291 14-Sep K.IPGLVTLK[136.11].K "sp|Q9UK61|TASOR_HUMAN,tr|A0A087X0F1|A0A087X0F1_HUMAN" 2 847.5622 1.8 39014 14638 2 847.562581 424.7884 Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3 8.75 3118 - 538422 - - - 0.4023 - 1.341 0.219 - 153.5 1 2 0 0.0003 8 0 0 0 2.21E+07 1.22E+07 - - - 1.5434 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.14639.14639.2 0.0263 14-Jul K.LLESDYFR.Y "sp|Q96HE7|ERO1A_HUMAN,tr|G3V503|G3V503_HUMAN,tr|G3V3E6|G3V3E6_HUMAN" 3 1041.5131 1.72 39015 14639 2 1041.510862 521.7638 ERO1-like protein alpha OS=Homo sapiens OX=9606 GN=ERO1A PE=1 SV=2 4.37 3118.2 - 474825 - - - -2.1594 - 1.519 0.369 - 138.6 1 2 0 -0.0022 8 0 0 0 1.16E+07 6.73E+06 - - - 3.0266 0.9951 230117_WJC_METTL3_WT_vs_EV_F05.14642.14642.2 0.311 16-Jun R.VIMSDLQIR[166.11].G "sp|Q9UIF9|BAZ2A_HUMAN,tr|A0A0C4DGI9|A0A0C4DGI9_HUMAN,tr|F8VU39|F8VU39_HUMAN,tr|J3KPG5|J3KPG5_HUMAN" 4 1083.5986 0.93 39018 14642 2 1083.600337 542.8066 Bromodomain adjacent to zinc finger domain protein 2A OS=Homo sapiens OX=9606 GN=BAZ2A PE=1 SV=4 5.81 3118.5 - 188731 - - - 1.6168 - 1.169 0.204 - 85 1 2 0 0.0018 9 0 0 0 1.92E+06 2.06E+06 - - - 0.9989 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.14645.14645.2 0.00548 12-Aug K.VSTVFWK[136.11].S sp|Q14152|EIF3A_HUMAN 1 873.484 0.82 39019 14645 2 873.48504 437.7493 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.72 3118.9 - 2.23E+06 - - - 1.2021 - 1.741 0.324 - 206.9 1 2 0 0.001 7 0 0 0 6.29E+07 7.68E+07 - - - 3.1906 0.999 230117_WJC_METTL3_WT_vs_EV_F05.14647.14647.2 4.27 16-Sep K.LGIIGVVNR.S "sp|O00429|DNM1L_HUMAN,tr|F8VZ52|F8VZ52_HUMAN" 2 939.5866 1.46 39021 14647 2 939.588455 470.8006 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 9.75 3119.1 - 2.48E+06 - - - 2.0264 - 1.874 0.23 - 184.6 1 2 0 0.0019 9 0 0 0 5.80E+07 3.97E+07 - - - 2.5562 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.14655.14655.2 0.0446 14-Jul K.IIYIAPMR[166.11].S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 985.5658 1.37 39026 14655 2 985.567523 493.7902 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 3120.1 - 3.86E+06 - - - 1.7188 - 1.507 0.261 - 163.1 1 2 0 0.0017 8 0 0 0 1.02E+08 7.42E+07 - - - 2.2051 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.14658.14658.2 0.0555 12-Aug K.FDLMYAK.R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 886.4259 3.23 39029 14658 2 886.427411 444.2202 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3120.4 - 1.55E+06 - - - 1.7317 - 1.532 0.34 - 208.2 1 2 0 0.0015 7 0 0 0 6.95E+08 2.15E+08 - - - 2.9034 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.14668.14668.2 16.1 12-Aug K.IGIEIIK.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 784.5058 2.31 39035 14668 2 784.506797 393.2602 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3121.7 - 4.01E+06 - - - 1.2186 - 1.738 0.042 - 155.2 1 2 0 0.001 7 0 0 0 4.23E+07 1.83E+07 - - - 1.1023 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.14678.14678.2 0.00127 12-Jul K.FDLMYAK[136.11].R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 894.4401 3.23 39042 14678 2 894.440189 448.2273 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3122.8 - 1.54E+06 - - - 0.1263 - 1.547 0.287 - 139.1 1 2 0 0.0001 7 0 0 0 6.95E+08 2.15E+08 - - - 2.5432 0.9847 230117_WJC_METTL3_WT_vs_EV_F05.14685.14685.2 0.033 14-Jul K.LTPLLSVR[166.11].E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 907.573 0.91 39047 14685 2 907.574902 454.7938 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3123.4 - 3.67E+06 - - - 2.0704 - 1.254 0.074 - 213.5 1 2 0 0.0019 8 0 0 0 1.93E+08 2.13E+08 - - - 0.2696 0.9935 230117_WJC_METTL3_WT_vs_EV_F05.14686.14686.2 0.0318 14-Jul K.LTPLLSVR.E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 897.5648 0.91 39048 14686 2 897.567404 449.7897 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3123.5 - 2.77E+06 - - - 2.9535 - 1.195 0.222 - 209 1 2 0 0.0027 8 0 0 0 1.93E+08 2.13E+08 - - - 1.2171 0.9593 230117_WJC_METTL3_WT_vs_EV_F05.14687.14687.2 4.38 12-May K.LVLILNK.S "sp|Q9BVP2|GNL3_HUMAN,sp|Q96RW7|HMCN1_HUMAN" 2 811.5531 0.92 39049 14687 2 811.554781 406.7838 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.75 3123.6 - 1.33E+06 - - - 2.0405 - 1.194 0.056 - 81.3 8 2 0 0.0017 7 0 0 0 5.05E+07 5.48E+07 - - - -0.3875 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.14697.14697.2 0.0771 16-Sep K.GFVTADMIR[166.11].E sp|Q9UHQ9|NB5R1_HUMAN 1 1018.5145 2.03 39057 14697 2 1018.516499 510.2645 NADH-cytochrome b5 reductase 1 OS=Homo sapiens OX=9606 GN=CYB5R1 PE=1 SV=1 5.84 3124.8 - 431310 - - - 1.942 - 1.798 0.348 - 239.9 1 2 0 0.002 9 0 0 0 1.15E+07 5.67E+06 - - - 3.308 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.14703.14703.2 0.0284 12-Aug R.FC[160.03]DVLLR.V "sp|Q9HBE1|PATZ1_HUMAN,tr|B1ARF3|B1ARF3_HUMAN" 2 921.4742 0.03 39061 14703 2 921.475658 461.7444 "POZ-, AT hook-, and zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=PATZ1 PE=1 SV=1" 5.83 3125.7 - 436631 - - - 1.5573 - 1.405 0.281 - 226.6 1 2 0 0.0014 7 0 0 0 1.62E+07 5.40E+08 - - - 2.1934 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.14704.14704.2 0.00359 18-Sep R.VLLGEGVLTK[136.11].E "sp|Q96S99|PKHF1_HUMAN,sp|Q9H8W4|PKHF2_HUMAN,tr|K7ELB8|K7ELB8_HUMAN,tr|K7EIX0|K7EIX0_HUMAN" 4 1035.6419 0.76 39062 14704 2 1035.642336 518.8282 Pleckstrin homology domain-containing family F member 1 OS=Homo sapiens OX=9606 GN=PLEKHF1 PE=1 SV=3 5.97 3125.8 - 1.45E+06 - - - 0.3756 - 1.845 0.457 - 201 1 2 0 0.0004 10 0 0 0 2.61E+07 3.44E+07 - - - 4.1259 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.14706.14706.2 0.0144 16-Sep K.GFVTADMIR.E sp|Q9UHQ9|NB5R1_HUMAN 1 1008.5063 1.65 39064 14706 2 1008.50892 505.2604 NADH-cytochrome b5 reductase 1 OS=Homo sapiens OX=9606 GN=CYB5R1 PE=1 SV=1 5.84 3126.1 - 448330 - - - 2.6465 - 1.701 0.374 - 275.3 1 2 0 0.0027 9 0 0 0 1.17E+07 7.10E+06 - - - 3.3394 0.9835 230117_WJC_METTL3_WT_vs_EV_F05.14712.14712.2 1.21 12-May K.LFQPFGK[136.11].V sp|Q14966|ZN638_HUMAN 1 843.4734 1.2 39068 14712 2 843.474004 422.744 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 8.75 3126.7 - 1.25E+06 - - - 0.6864 - 1.197 0.097 - 71.8 2 2 0 0.0006 7 0 0 0 3.95E+07 3.31E+07 - - - 0.1926 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.14719.14719.2 0.00792 14-Aug R.LYELDGLR.E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 977.5182 2.8 39073 14719 2 977.518816 489.7664 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3127.6 - 944441 - - - 0.6343 - 1.472 0.341 - 226.1 1 2 0 0.0006 8 0 0 0 5.78E+08 2.07E+08 - - - 2.7255 0.9832 230117_WJC_METTL3_WT_vs_EV_F05.14721.14721.2 9.42 12-Jun R.AVTIFIR.G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 818.5014 4.44 39074 14721 2 818.502624 410.258 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3127.9 - 4.83E+06 - - - 1.4661 - 1.208 0.065 - 176.1 1 2 0 0.0012 7 0 0 0 2.17E+09 4.88E+08 - - - 0.1195 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.14723.14723.2 0.112 14-Aug R.LYELDGLR[166.11].E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 987.5265 2.8 39076 14723 2 987.528673 494.7705 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3128.1 - 487243 - - - 2.2349 - 1.755 0.271 - 188.8 1 2 0 0.0022 8 0 0 0 5.79E+08 2.07E+08 - - - 2.7383 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.14729.14729.2 0.087 16-Jul K.IPFASLASR[166.11].L sp|P35573|GDE_HUMAN 1 970.5475 1.86 39080 14729 2 970.548317 486.281 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3128.9 - 432885 - - - 0.8047 - 1.458 0.267 - 115.4 1 2 0 0.0008 9 0 0 0 2.66E+07 1.43E+07 - - - 2.1037 0.9775 230117_WJC_METTL3_WT_vs_EV_F05.14730.14730.2 1.25 12-Jun R.ELFVMAR[166.11].E "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QSA9|J3QSA9_HUMAN" 4 874.461 5.39 39081 14730 2 874.464167 438.2378 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 6.1 3128.9 - 1.24E+06 - - - 3.5885 - 1.285 0.101 - 166.2 1 2 0 0.0031 7 0 0 0 1.53E+08 2.84E+07 - - - 0.5805 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.14743.14743.2 0.0277 12-Jun R.ELFVMAR.E "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QSA9|J3QSA9_HUMAN" 4 864.4528 5.45 39089 14743 2 864.452463 433.2337 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 6.1 3130.7 - 2.12E+06 - - - -0.3424 - 1.269 0.318 - 181.8 1 2 0 -0.0003 7 0 0 0 1.57E+08 2.89E+07 - - - 2.1445 0.9718 230117_WJC_METTL3_WT_vs_EV_F05.14745.14745.2 0.681 12-May R.AVTIFIR[166.11].G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 828.5097 4.42 39090 14745 2 828.509194 415.2621 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3131 - 3.38E+06 - - - -0.6035 - 1.346 0.056 - 103.5 2 2 0 -0.0005 7 0 0 0 2.17E+09 4.90E+08 - - - 0.2615 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.14752.14752.2 0.00569 16-Aug K.IPFASLASR.L sp|P35573|GDE_HUMAN 1 960.5393 0.16 39095 14752 2 960.54087 481.2769 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3131.8 - 549667 - - - 1.6699 - 1.578 0.339 - 175 1 2 0 0.0016 9 0 0 0 2.76E+07 1.71E+08 - - - 2.864 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.14756.14756.2 0.231 16-Aug K.LISYSYMVR[166.11].G sp|P07099|HYEP_HUMAN 1 1140.5877 0.96 39097 14756 2 1140.587476 571.3011 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 8.59 3132.3 - 949497 - - - -0.1841 - 1.6 0.266 - 165.4 1 2 0 -0.0002 9 0 0 0 1.64E+07 1.71E+07 - - - 2.3654 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.14762.14762.2 0.0898 12-Jul R.IVFQEFR[166.11].Q "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN" 2 947.5104 0.78 39101 14762 2 947.51008 474.7625 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3133.1 - 3.31E+06 - - - -0.3609 - 1.446 0.221 - 197.1 1 2 0 -0.0003 7 0 0 0 1.86E+08 2.39E+08 - - - 1.8418 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.14783.14783.2 0.000135 13/22 K.FAQALGLTEAVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1246.6921 1.15 39110 14783 2 1246.690805 624.3533 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3135.9 - 0 - - - -1.0692 - 2.467 0.416 - 576.9 1 2 0 -0.0013 12 0 0 0 2.47E+07 2.15E+07 - - - 4.4891 1 230117_WJC_METTL3_WT_vs_EV_F05.14793.14793.2 6.05E-07 22-Dec K.FAQALGLTEAVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1254.7063 1.15 39113 14793 2 1254.706108 628.3604 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3137.3 - 1.55E+06 - - - -0.1833 - 2.492 0.48 - 460.8 1 2 0 -0.0002 12 0 0 0 2.47E+07 2.15E+07 - - - 4.9887 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.14794.14794.2 0.0497 18-Dec R.INEILSNALK.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 3 1113.6394 6.45 39114 14794 2 1113.639656 557.827 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3137.4 - 971455 - - - 0.2532 - 1.956 0.198 - 401.1 1 2 0 0.0003 10 0 0 0 1.67E+07 2.60E+06 - - - 2.376 0.9646 230117_WJC_METTL3_WT_vs_EV_F05.14797.14797.2 5.11 12-Jun K.LGFEEFK.Y "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 868.4331 2.48 39115 14797 2 868.432771 435.2238 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 3137.8 - 3.62E+06 - - - -0.3443 - 1.098 0.09 - 95.6 1 2 0 -0.0003 7 0 0 0 1.95E+08 7.88E+07 - - - 0.0019 0.9874 230117_WJC_METTL3_WT_vs_EV_F05.14800.14800.2 0.0227 12-Jul K.LGFEEFK[136.11].Y "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 876.4473 2.48 39117 14800 2 876.44535 439.2309 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 3138.1 - 1.51E+06 - - - -2.1907 - 1.582 0.155 - 138.6 1 2 0 -0.0019 7 0 0 0 1.96E+08 7.88E+07 - - - 1.6386 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.14801.14801.2 0.024 14-Aug R.DAFVYAIK.N "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 925.4909 0.86 39118 14801 2 925.49079 463.7527 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 5.83 3138.2 - 1.17E+06 - - - -0.1394 - 1.409 0.285 - 258.7 1 2 0 -0.0001 8 0 0 0 1.17E+08 1.36E+08 - - - 2.1801 0.9135 230117_WJC_METTL3_WT_vs_EV_F05.14807.14807.2 0.000567 14-Aug R.YPDGIISK.P sp|Q86U44|MTA70_HUMAN 1 891.4702 17.05 39121 14807 2 891.469548 446.7424 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3138.9 - 1.52E+06 - - - -0.7123 - 1.397 0.42 - 169.1 1 1 0 -0.0006 8 0 0 0 1.63E+08 9.53E+06 - - - 3.1512 0.9436 230117_WJC_METTL3_WT_vs_EV_F05.14809.14809.2 0.874 12-Jun K.YLPDIIK.D sp|O15355|PPM1G_HUMAN 1 860.5008 3.25 39122 14809 2 860.499526 431.2577 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 5.83 3139.1 - 2.58E+06 - - - -1.4282 - 0.956 0.167 - 120.2 1 2 0 -0.0012 7 0 0 0 1.61E+08 4.96E+07 - - - 0.1315 0.9928 230117_WJC_METTL3_WT_vs_EV_F05.14817.14817.2 0.449 14-Jun K.LLFYATSR.A "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 969.5284 0.43 39126 14817 2 969.52622 485.7715 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 8.75 3140.1 - 1.34E+06 - - - -2.2145 - 1.35 0.301 - 103.5 1 2 0 -0.0021 8 0 0 0 4.52E+07 1.04E+08 - - - 2.1686 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.14821.14821.2 0.249 16-Sep R.AFSYYGPLR[166.11].T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1082.5425 0.88 39128 14821 2 1082.540545 542.2785 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3140.6 - 1.73E+06 - - - -1.7607 - 1.856 0.337 - 311.5 1 2 0 -0.0019 9 0 0 0 2.59E+08 2.94E+08 - - - 3.3186 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.14825.14825.2 0.00065 16-Sep R.AFSYYGPLR.T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1072.5342 0.88 39130 14825 2 1072.535515 537.2744 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3141.2 - 993201 - - - 1.2438 - 1.647 0.516 - 288.8 1 2 0 0.0013 9 0 0 0 2.59E+08 2.94E+08 - - - 4.2953 0.9944 230117_WJC_METTL3_WT_vs_EV_F05.14840.14840.2 0.122 16-Aug R.ILDSAEFIK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1042.579 0.94 39138 14840 2 1042.57743 522.2968 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3143.2 - 2.04E+06 - - - -1.5174 - 1.672 0.198 - 99.5 1 2 0 -0.0016 9 0 0 0 6.25E+09 6.68E+09 - - - 1.99 0.9946 230117_WJC_METTL3_WT_vs_EV_F05.14842.14842.2 0.0212 14-Jun R.IVAEEFLK.N "sp|P59998|ARPC4_HUMAN,tr|H7C0A3|H7C0A3_HUMAN,tr|F8WCF6|F8WCF6_HUMAN,tr|R4GN08|R4GN08_HUMAN" 4 947.5328 0.42 39140 14842 2 947.531825 474.7737 Actin-related protein 2\3 complex subunit 4 OS=Homo sapiens OX=9606 GN=ARPC4 PE=1 SV=3 4.53 3143.4 - 1.59E+06 - - - -1.0121 - 1.355 0.239 - 63.7 1 2 0 -0.001 8 0 0 0 6.82E+06 1.61E+07 - - - 1.7222 0.8645 230117_WJC_METTL3_WT_vs_EV_F05.14845.14845.2 19.5 12-Jun K.YVLALVK[136.11].K "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 812.5251 1.4 39143 14845 2 812.524181 407.2698 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.59 3143.8 - 775872 - - - -1.163 - 1.25 0.009 - 118.1 8 2 0 -0.0009 7 0 0 0 5.33E+07 3.80E+07 - - - -0.5892 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.14849.14849.2 0.0383 16-Oct R.ILDSAEFIK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1034.5648 0.94 39145 14849 2 1034.566401 518.2897 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3144.2 - 4.94E+06 - - - 1.5359 - 1.784 0.385 - 226.6 1 2 0 0.0016 9 0 0 0 6.25E+09 6.68E+09 - - - 3.5588 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.14853.14853.2 0.0457 12-Jul K.YNIMLVR.L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 907.495 8.3 39148 14853 2 907.493748 454.7548 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3144.6 - 2.35E+06 - - - -1.3333 - 1.507 0.273 - 211.3 1 2 0 -0.0012 7 0 0 0 1.61E+09 1.94E+08 - - - 2.3565 0.9899 230117_WJC_METTL3_WT_vs_EV_F05.14868.14868.2 0.271 12-Jul K.YNIMLVR[166.11].L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 917.5032 8.29 39154 14868 2 917.501103 459.7589 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3146.6 - 1.76E+06 - - - -2.3161 - 1.433 0.234 - 192.1 1 2 0 -0.0021 7 0 0 0 1.61E+09 1.94E+08 - - - 1.9086 0.9923 230117_WJC_METTL3_WT_vs_EV_F05.14889.14889.2 0.12 12-Jul R.LNLYELK.E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 891.5066 2.04 39164 14889 2 891.506482 446.7606 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3149.5 - 2.33E+06 - - - -0.0976 - 1.472 0.125 - 158.4 3 2 0 -0.0001 7 0 0 0 1.90E+08 9.29E+07 - - - 0.9761 0.9944 230117_WJC_METTL3_WT_vs_EV_F05.14895.14895.2 0.00775 16-Aug K.YLPELMAEK[136.11].D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1100.5667 1.1 39166 14895 2 1100.565145 551.2906 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3150.3 - 1.17E+06 - - - -1.4429 - 1.285 0.295 - 203.2 1 2 0 -0.0016 9 0 0 0 1.01E+08 9.16E+07 - - - 1.9448 0.9871 230117_WJC_METTL3_WT_vs_EV_F05.14900.14900.2 0.403 12-Aug R.LNLYELK[136.11].E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 899.5208 2.02 39168 14900 2 899.518683 450.7677 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3150.9 - 3.91E+06 - - - -2.319 - 1.621 0.152 - 201.8 1 2 0 -0.0021 7 0 0 0 1.90E+08 9.40E+07 - - - 1.6936 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.14902.14902.2 0.0145 20-Aug K.LVLLGESAVGK.S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1084.6492 1.52 39170 14902 2 1084.647909 543.3319 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3151.2 - 4.81E+06 - - - -1.2004 - 1.774 0.234 - 153.7 1 2 0 -0.0013 11 0 0 0 1.06E+08 7.00E+07 - - - 2.3197 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.14903.14903.2 0.0163 20-Nov K.LVLLGESAVGK[136.11].S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1092.6634 1.52 39171 14903 2 1092.661204 547.339 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3151.3 - 3.46E+06 - - - -2.0198 - 2.11 0.338 - 300.8 1 2 0 -0.0022 11 0 0 0 1.06E+08 7.00E+07 - - - 3.5567 0.9946 230117_WJC_METTL3_WT_vs_EV_F05.14915.14915.2 0.0313 16-Aug K.YLPELMAEK.D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1092.5525 1.1 39176 14915 2 1092.550371 547.2835 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3152.9 - 3.04E+06 - - - -1.9789 - 1.259 0.352 - 171.4 1 2 0 -0.0022 9 0 0 0 1.01E+08 9.16E+07 - - - 2.3065 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.14922.14922.2 0.188 14-Jul R.VMLYPSRI.- sp|P18077|RL35A_HUMAN 1 977.5368 0.94 39179 14922 2 977.538419 489.7757 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.72 3153.9 - 2.18E+06 - - - 1.6327 - 1.342 0.201 - 206.4 1 2 0 0.0016 8 0 0 0 7.39E+07 7.83E+07 - - - 1.4123 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.14924.14924.2 0.059 12-Jul K.FADFMVK.D "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 14 856.4153 1.84 39180 14924 2 856.413797 429.2149 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 5.84 3154.1 - 1.31E+06 - - - -1.7678 - 1.33 0.365 - 124.4 1 2 0 -0.0015 7 0 0 0 3.16E+07 1.72E+07 - - - 2.64 0.998 230117_WJC_METTL3_WT_vs_EV_F05.14935.14935.2 0.0253 20-Dec R.MGAGMGFGLER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1134.519 2.28 39186 14935 2 1134.516696 568.2668 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 3155.5 - 827168 - - - -1.9912 - 1.95 0.378 - 259.5 1 2 0 -0.0023 11 0 0 0 4.79E+07 2.10E+07 - - - 3.6388 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.14937.14937.2 0.0233 12-Jul K.FADFMVK[136.11].D "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 14 864.4295 1.84 39187 14937 2 864.428476 433.222 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 5.84 3155.7 - 648064 - - - -1.1973 - 1.286 0.369 - 85.1 1 2 0 -0.001 7 0 0 0 3.16E+07 1.72E+07 - - - 2.5631 0.9736 230117_WJC_METTL3_WT_vs_EV_F05.14947.14947.2 0.795 12-Jul K.LILEYVK.A "sp|Q7L5N1|CSN6_HUMAN,tr|E7EM64|E7EM64_HUMAN" 2 876.5321 2.13 39194 14947 2 876.532584 439.2733 COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1 6 3156.8 - 1.24E+06 - - - 0.6035 - 1.28 0.01 - 138.2 1 2 0 0.0005 7 0 0 0 2.87E+07 1.35E+07 - - - -0.1031 0.995 230117_WJC_METTL3_WT_vs_EV_F05.14954.14954.2 0.0178 12-Aug K.WDPVVLK.N sp|Q9BVJ6|UT14A_HUMAN 1 855.4854 1.31 39199 14954 2 855.485344 428.75 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 5.84 3157.6 - 1.97E+06 - - - -0.1122 - 1.03 0.297 - 185.2 1 2 0 -0.0001 7 0 0 0 6.75E+07 5.17E+07 - - - 1.3283 0.8779 230117_WJC_METTL3_WT_vs_EV_F05.14955.14955.2 0.545 14-Jul R.PIVTVWER[166.11].E "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EQR8|K7EQR8_HUMAN" 3 1008.5632 2.69 39200 14955 2 1008.563206 505.2889 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 6.43 3157.8 - 1.38E+06 - - - 0.0198 - 1.595 0.237 - 187.5 1 1 0 0 8 0 0 0 9.99E+07 3.71E+07 - - - 2.1995 1 230117_WJC_METTL3_WT_vs_EV_F05.14958.14958.2 2.65E-09 15/26 R.VPTANVSVVDLTC[160.03]R.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1529.7872 4.11 39203 14958 2 1529.791749 765.9009 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3158.2 - 453797 - - - 2.988 - 2.901 0.646 - 692.9 1 2 0 0.0046 14 0 0 0 5.73E+06 1.39E+06 - - - 6.4836 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.14961.14961.2 0.641 14-May R.VMLYPSR[166.11]I.- sp|P18077|RL35A_HUMAN 1 987.5451 0.87 39205 14961 2 987.544725 494.7798 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.72 3158.5 - 2.70E+06 - - - -0.3726 - 1.351 0.215 - 122 1 2 0 -0.0004 8 0 0 0 6.78E+07 7.83E+07 - - - 1.5362 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.14965.14965.2 2.05 14-Jun K.IEPPGLFR[166.11].G "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|E5RJ95|E5RJ95_HUMAN,tr|E5RIC7|E5RIC7_HUMAN,tr|E5RFS0|E5RFS0_HUMAN" 5 937.5261 0.71 39208 14965 2 937.526871 469.7703 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 6 3158.9 - 3.58E+06 - - - 0.8522 - 1.17 0.243 - 141.5 1 2 0 0.0008 8 0 0 0 8.04E+07 1.14E+08 - - - 1.3091 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.14967.14967.2 0.00301 14-Aug K.LIYLVPEK.Q "sp|Q9NZM3|ITSN2_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN,tr|E7EPJ2|E7EPJ2_HUMAN" 3 973.5848 3.46 39210 14967 2 973.585237 487.7997 Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3 6 3159.2 - 693857 - - - 0.4293 - 1.52 0.36 - 188.3 1 2 0 0.0004 8 0 0 0 2.89E+07 8.34E+06 - - - 2.9626 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.14981.14981.2 0.0131 14-Sep R.LLEIVSYK.L "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 963.5641 1.01 39218 14981 2 963.565783 482.7893 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6 3160.9 - 320692 - - - 1.7632 - 1.733 0.402 - 211.7 1 2 0 0.0017 8 0 0 0 6.60E+07 6.54E+07 - - - 3.668 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.14982.14982.2 0.353 12-Jul R.DLGAYLR.Q "sp|Q9BRT2|UQCC2_HUMAN,tr|Q5TAQ0|Q5TAQ0_HUMAN,tr|V5IRT4|V5IRT4_HUMAN" 3 806.4287 0.17 39219 14982 2 806.430165 404.2216 Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1 5.84 3161 - 508359 - - - 1.8749 - 1.504 0.12 - 153 1 2 0 0.0015 7 0 0 0 4.84E+06 2.78E+07 - - - 1.22 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.14989.14989.2 0.0994 14-Sep R.VGEIVVFR[166.11].L "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 927.5417 2.12 39222 14989 2 927.543423 464.7781 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.97 3161.9 - 1.75E+06 - - - 1.8339 - 1.592 0.347 - 308.6 1 2 0 0.0017 8 0 0 0 5.25E+07 2.48E+07 - - - 3.0058 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.15002.15002.2 0.000277 14-Sep R.VGEIVVFR.L "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 917.5335 2.1 39230 15002 2 917.534752 459.774 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.97 3163.5 - 2.30E+06 - - - 1.4168 - 1.98 0.436 - 317 1 2 0 0.0013 8 0 0 0 5.36E+07 2.55E+07 - - - 4.3211 0.9485 230117_WJC_METTL3_WT_vs_EV_F05.15008.15008.2 2.91 14-Jul K.GAIEVLIR.E "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 869.5335 1.16 39234 15008 2 869.535926 435.774 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 6 3164.1 - 985700 - - - 2.8452 - 1.325 0.004 - 134.8 3 2 0 0.0025 8 0 0 0 3.26E+07 2.81E+07 - - - -0.2946 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.15010.15010.2 0.00184 16-Jul K.ANPALYVLR[166.11].E sp|Q6P2Q9|PRP8_HUMAN 1 1025.5897 1.31 39236 15010 2 1025.592116 513.8021 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.79 3164.3 - 1.13E+06 - - - 2.3216 - 1.528 0.353 - 173.9 1 2 0 0.0024 9 0 0 0 8.01E+07 6.12E+07 - - - 2.874 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.15011.15011.2 0.524 14-Oct K.GAIEVLIR[166.11].E "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 879.5417 1.15 39237 15011 2 879.543135 440.7781 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 6 3164.5 - 986534 - - - 1.6065 - 1.997 0.22 - 260.7 1 2 0 0.0014 8 0 0 0 3.26E+07 2.84E+07 - - - 2.7514 1 230117_WJC_METTL3_WT_vs_EV_F05.15013.15013.2 6.21E-08 28-Dec R.NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1656.8459 4.79 39239 15013 2 1656.847376 829.4302 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3164.7 - 503365 - - - 0.889 - 2.681 0.466 - 309.3 1 2 0 0.0015 15 0 0 0 3.31E+07 6.91E+06 - - - 4.907 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.15020.15020.2 0.0016 16-Nov K.ELGVGIALR.K sp|Q01469|FABP5_HUMAN 1 926.5549 12.24 39244 15020 2 926.556789 464.2847 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 6.1 3165.6 - 3.05E+06 - - - 2.0215 - 1.978 0.374 - 489.3 1 2 0 0.0019 9 0 0 0 1.09E+08 8.88E+06 - - - 3.7761 0.9259 230117_WJC_METTL3_WT_vs_EV_F05.15024.15024.3 0.0187 Oct-44 R.YLYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1484.8126 0.08 39248 15024 3 1484.814942 495.9448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3166 - 450247 - - - 1.5456 - 1.521 0.308 - 81.9 1 2 1 0.0023 12 0 0 0 5.73E+06 6.92E+07 - - - 3.1357 0.999 230117_WJC_METTL3_WT_vs_EV_F05.15025.15025.2 0.000396 28-Dec R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 0.63 39249 15025 2 1646.835182 824.4261 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3166.1 - 293951 - - - -1.4883 - 2.066 0.468 - 212.3 1 2 0 -0.0025 15 0 0 0 2.65E+06 4.22E+06 - - - 4.2808 0.9694 230117_WJC_METTL3_WT_vs_EV_F05.15030.15030.2 0.113 12-Apr K.LVPGLFK[136.11].N "sp|P35226|BMI1_HUMAN,sp|P35227|PCGF2_HUMAN,tr|Q5T8Z6|Q5T8Z6_HUMAN,tr|A0A087X259|A0A087X259_HUMAN,tr|J3KT13|J3KT13_HUMAN,tr|R4GMX3|R4GMX3_HUMAN,tr|Q5T8Z4|Q5T8Z4_HUMAN" 7 780.4989 1.32 39252 15030 2 780.500885 391.2567 Polycomb complex protein BMI-1 OS=Homo sapiens OX=9606 GN=BMI1 PE=1 SV=2 8.75 3166.8 - 950249 - - - 2.5292 - 0.887 0.191 - 55.1 2 2 0 0.002 7 0 0 0 5.21E+07 3.94E+07 - - - -0.0633 0.9902 230117_WJC_METTL3_WT_vs_EV_F05.15031.15031.2 1.14 12-Jul K.TLLDSLR[166.11].S sp|Q5JTH9|RRP12_HUMAN 1 826.4788 0.74 39253 15031 2 826.480998 414.2467 RRP12-like protein OS=Homo sapiens OX=9606 GN=RRP12 PE=1 SV=2 5.5 3166.9 - 712332 - - - 2.674 - 1.354 0.106 - 161.5 1 2 0 0.0022 7 0 0 0 2.65E+07 3.60E+07 - - - 0.7835 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.15032.15032.2 0.00318 14-Jun K.FLVGFTNK[136.11].G "sp|P43307|SSRA_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|C9J5W0|C9J5W0_HUMAN" 6 932.5211 1.45 39254 15032 2 932.523013 467.2678 Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3 8.75 3167 - 1.26E+06 - - - 2.0482 - 1.538 0.426 - 98.8 1 2 0 0.0019 8 0 0 0 2.05E+08 1.41E+08 - - - 3.4852 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.15033.15033.2 0.000563 16-Oct R.AFGYYGPLR[166.11].S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1052.5319 0.99 39255 15033 2 1052.533959 527.2732 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3167.1 - 1.00E+06 - - - 1.9695 - 2.051 0.446 - 399.9 1 2 0 0.0021 9 0 0 0 1.12E+09 1.13E+09 - - - 4.4127 0.955 230117_WJC_METTL3_WT_vs_EV_F05.15035.15035.2 1.45 12-Jun K.LYGFPYK[136.11].L "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 894.4731 1.05 39257 15035 2 894.472072 448.2438 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 8.5 3167.3 - 519677 - - - -1.1381 - 1.104 0.11 - 95.4 1 2 0 -0.001 7 0 0 0 2.18E+07 2.09E+07 - - - 0.1666 0.9848 230117_WJC_METTL3_WT_vs_EV_F05.15036.15036.2 0.97 16-Sep K.MLLYTEVTR[166.11].Y "sp|P31150|GDIA_HUMAN,sp|P50395|GDIB_HUMAN,tr|G5E9U5|G5E9U5_HUMAN,tr|Q5SX86|Q5SX86_HUMAN,tr|Q5SX90|Q5SX90_HUMAN,tr|V9GYF8|V9GYF8_HUMAN,tr|V9GYJ7|V9GYJ7_HUMAN" 7 1134.5983 1.3 39258 15036 2 1134.602203 568.3064 Rab GDP dissociation inhibitor alpha OS=Homo sapiens OX=9606 GN=GDI1 PE=1 SV=2 5.75 3167.5 - 429219 - - - 3.4832 - 1.432 0.1 - 189.5 1 2 0 0.004 9 0 0 0 1.75E+07 1.35E+07 - - - 0.8172 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.15043.15043.2 0.00324 16-Aug R.AFGYYGPLR.S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1042.5236 0.99 39263 15043 2 1042.525331 522.2691 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3168.2 - 2.34E+06 - - - 1.645 - 1.289 0.413 - 273.2 1 2 0 0.0017 9 0 0 0 1.12E+09 1.13E+09 - - - 2.8253 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.15044.15044.2 9.28 12-Jun R.LIVDVIR.F "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 826.5276 1.21 39264 15044 2 826.528538 414.2711 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.84 3168.3 - 2.25E+06 - - - 1.0877 - 1.321 0.18 - 121.3 1 2 0 0.0009 7 0 0 0 6.58E+07 5.44E+07 - - - 1.2523 0.9934 230117_WJC_METTL3_WT_vs_EV_F05.15048.15048.2 0.616 16-Jul K.LQVALGELR[166.11].R sp|P19474|RO52_HUMAN 1 1007.6003 1.48 39268 15048 2 1007.602262 504.8074 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 6 3168.6 - 832568 - - - 1.9472 - 1.65 0.075 - 143.8 3 2 0 0.002 9 0 0 0 1.37E+07 9.27E+06 - - - 0.83 0.9964 230117_WJC_METTL3_WT_vs_EV_F05.15049.15049.2 0.116 18-Aug R.FLSTTIVYPK[136.11].Y sp|Q8N5W9|RFLB_HUMAN 1 1175.6682 2.1 39269 15049 2 1175.67248 588.8414 Refilin-B OS=Homo sapiens OX=9606 GN=RFLNB PE=1 SV=1 8.59 3168.7 - 329414 - - - 3.6728 - 1.265 0.329 - 158.4 1 2 0 0.0043 10 0 0 0 1.05E+07 4.98E+06 - - - 2.1258 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.15070.15070.2 0.145 12-Jul R.QMSLLLR.R sp|P25705|ATPA_HUMAN 1 859.495 1.58 39283 15070 2 859.496053 430.7548 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 9.75 3171.4 - 4.86E+06 - - - 1.274 - 1.534 0.163 - 325.5 1 2 0 0.0011 7 0 0 0 2.11E+08 1.33E+08 - - - 1.6003 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.15074.15074.2 0.00355 20-Nov R.VFSGLVSTGLK.V sp|P13639|EF2_HUMAN 1 1106.6336 4.03 39287 15074 2 1106.635545 554.3241 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.72 3171.8 - 545399 - - - 1.7937 - 1.942 0.419 - 338.3 1 2 0 0.002 11 0 0 0 9.27E+07 2.30E+07 - - - 3.9306 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.15079.15079.2 0.0468 16-Oct R.LLGYVATLK[136.11].D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 984.6099 2.43 39290 15079 2 984.612732 493.3122 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 8.59 3172.4 - 1.47E+06 - - - 2.858 - 1.801 0.333 - 200.2 1 2 0 0.0028 9 0 0 0 2.97E+08 1.22E+08 - - - 3.2018 1 230117_WJC_METTL3_WT_vs_EV_F05.15080.15080.2 2.95E-05 16-Oct K.YMAC[160.03]C[160.03]LLYR.G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1248.5454 3.21 39291 15080 2 1248.547734 625.28 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3172.5 - 283597 - - - 1.9046 - 1.869 0.638 - 455.7 1 2 0 0.0024 9 0 0 0 2.10E+08 6.53E+07 - - - 5.5618 1 230117_WJC_METTL3_WT_vs_EV_F05.15090.15090.2 0.000145 16-Sep K.YMAC[160.03]C[160.03]LLYR[166.11].G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1258.5536 3.21 39296 15090 2 1258.554125 630.2841 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3173.7 - 207538 - - - 0.3965 - 1.632 0.584 - 325.4 1 2 0 0.0005 9 0 0 0 2.10E+08 6.53E+07 - - - 4.7713 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.15094.15094.2 0.119 16-Aug K.LVELPYTVK.G sp|Q9NPF4|OSGEP_HUMAN 1 1060.6168 1.94 39298 15094 2 1060.619739 531.3157 Probable tRNA N6-adenosine threonylcarbamoyltransferase OS=Homo sapiens OX=9606 GN=OSGEP PE=1 SV=1 6 3174.2 - 811236 - - - 2.7258 - 1.5 0.271 - 175 1 2 0 0.0029 9 0 0 0 2.92E+07 1.50E+07 - - - 2.2147 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15100.15100.2 0.00916 14-Jul K.AFAMIIDK.L "sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BND9|H3BND9_HUMAN" 8 907.4837 2.61 39302 15100 2 907.48394 454.7491 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 5.88 3174.8 - 1.39E+06 - - - 0.2369 - 1.624 0.395 - 162.3 1 2 0 0.0002 8 0 0 0 8.44E+07 3.24E+07 - - - 3.4208 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.15103.15103.2 0.00249 20-Nov R.IALTDNALIAR[166.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1179.6851 0.82 39304 15103 2 1179.688192 590.8498 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3175.1 - 208396 - - - 2.6278 - 2.294 0.117 - 330.9 1 2 0 0.0031 11 0 0 0 1.62E+07 1.99E+07 - - - 2.1503 0.9926 230117_WJC_METTL3_WT_vs_EV_F05.15112.15112.2 0.651 12-Jun K.EILFYDR[166.11].L sp|Q08J23|NSUN2_HUMAN 1 964.4894 1.85 39308 15112 2 964.489304 483.252 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.37 3176.3 - 1.94E+06 - - - -0.0498 - 1.297 0.153 - 151 1 2 0 0 7 0 0 0 1.01E+08 5.47E+07 - - - 0.995 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.15114.15114.2 0.0103 12-Jun K.EILFYDR.L sp|Q08J23|NSUN2_HUMAN 1 954.4811 1.85 39310 15114 2 954.481972 478.2478 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.37 3176.5 - 3.17E+06 - - - 0.9324 - 1.37 0.358 - 180.6 1 2 0 0.0009 7 0 0 0 1.01E+08 5.47E+07 - - - 2.6824 0.9863 230117_WJC_METTL3_WT_vs_EV_F05.15117.15117.2 2.15 12-Jul K.NLILVVR.G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 825.5436 1.14 39311 15117 2 825.543806 413.7791 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3176.9 - 2.81E+06 - - - 0.2217 - 1.402 0.045 - 190.4 1 2 0 0.0002 7 0 0 0 1.51E+08 1.32E+08 - - - 0.444 0.9832 230117_WJC_METTL3_WT_vs_EV_F05.15118.15118.2 2.8 12-Jul K.NLILVVR[166.11].G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 835.5519 1.14 39312 15118 2 835.55225 418.7832 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3177 - 2.78E+06 - - - 0.4273 - 1.259 0.064 - 271.6 1 2 0 0.0004 7 0 0 0 1.51E+08 1.32E+08 - - - 0.2434 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.15129.15129.2 0.000132 20-Oct R.IALTDNALIAR.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1169.6768 0.82 39319 15129 2 1169.67976 585.8457 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3178.3 - 580289 - - - 2.5118 - 2.155 0.411 - 261.8 1 2 0 0.0029 11 0 0 0 1.62E+07 1.99E+07 - - - 4.1528 0.998 230117_WJC_METTL3_WT_vs_EV_F05.15134.15134.2 0.908 16-Aug R.LLLPTPTVK.Q "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 980.627 2.43 39321 15134 2 980.627813 491.3208 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 3178.9 - 3.06E+06 - - - 0.8107 - 1.63 0.18 - 204.8 1 2 0 0.0008 9 0 0 0 3.46E+08 1.42E+08 - - - 1.7837 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.15140.15140.2 0.0164 14-Jul K.LIINSLYK.N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 962.5801 0.96 39323 15140 2 962.580583 482.2973 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3179.8 - 2.60E+06 - - - 0.535 - 1.287 0.321 - 90.7 1 2 0 0.0005 8 0 0 0 1.46E+08 1.53E+08 - - - 2.1727 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15147.15147.2 0.0173 14-Sep K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 2.81 39328 15147 2 843.507642 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 3180.6 - 1.69E+06 - - - 1.2721 - 1.69 0.316 - 220.6 1 2 0 0.0011 8 0 0 0 1.43E+08 5.07E+07 - - - 2.9572 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.15152.15152.2 0.429 14-Jul K.LIINSLYK[136.11].N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 970.5943 0.96 39331 15152 2 970.595207 486.3044 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3181.1 - 1.64E+06 - - - 0.9674 - 1.206 0.249 - 91.1 1 2 0 0.0009 8 0 0 0 1.46E+08 1.53E+08 - - - 1.4447 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.15154.15154.2 0.0107 12-Jul R.FLTVMMK[136.11].H "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 876.4693 1.28 39333 15154 2 876.470007 439.2419 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.75 3181.3 - 1.30E+06 - - - 0.8443 - 1.492 0.393 - 154.6 1 2 0 0.0007 7 0 0 0 2.13E+08 1.67E+08 - - - 3.2113 0.8695 230117_WJC_METTL3_WT_vs_EV_F05.15159.15159.3 0.737 May-36 R.LVVLGIR[166.11]PIR[166.11].L sp|Q92900|RENT1_HUMAN 1 1154.7766 0.03 39335 15159 3 1154.776538 385.9328 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 12 3182 - 2.07E+06 - - - -0.0866 - 0.985 0.187 - 27.2 12 2 0 -0.0001 10 0 0 0 1.94E+06 6.70E+07 - - - 0.0812 0.9571 230117_WJC_METTL3_WT_vs_EV_F05.15162.15162.2 2.41 12-May R.LYIWSGR[166.11].D "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 903.4842 2.5 39337 15162 2 903.484564 452.7494 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 8.75 3182.3 - 762290 - - - 0.394 - 1.072 0.068 - 89.9 2 2 0 0.0004 7 0 0 0 8.16E+07 3.27E+07 - - - -0.371 0.9918 230117_WJC_METTL3_WT_vs_EV_F05.15164.15164.2 0.278 16-Aug R.LPEAAFLAR.T "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 986.5549 2.74 39339 15164 2 986.554354 494.2847 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 6 3182.4 - 1.82E+06 - - - -0.5697 - 1.429 0.146 - 166.1 1 2 0 -0.0006 9 0 0 0 1.64E+08 5.98E+07 - - - 1.1519 0.9901 230117_WJC_METTL3_WT_vs_EV_F05.15168.15168.2 0.218 14-Jun K.NVPYVFVR[166.11].S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 1002.5526 1.1 39340 15168 2 1002.552337 502.2836 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3183 - 2.49E+06 - - - -0.2833 - 1.096 0.211 - 98.1 1 2 0 -0.0003 8 0 0 0 2.22E+08 2.02E+08 - - - 0.8758 0.9959 230117_WJC_METTL3_WT_vs_EV_F05.15201.15201.2 2.87 12-Aug K.YAWVLDK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 14 893.4647 2.09 39358 15201 2 893.467049 447.7396 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 3187.2 - 1.17E+06 - - - 2.6246 - 1.549 0.137 - 234.7 1 2 0 0.0023 7 0 0 0 8.77E+07 4.20E+07 - - - 1.4387 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.15211.15211.2 0.000961 16-Sep R.LLVHMGLLK.S sp|P46060|RAGP1_HUMAN 1 1022.6311 4.33 39364 15211 2 1022.632865 512.3228 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 8.76 3188.3 - 681336 - - - 1.767 - 1.818 0.409 - 193.5 1 2 0 0.0018 9 0 0 0 7.49E+06 1.73E+06 - - - 3.7906 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.15228.15228.2 0.714 18-Sep K.IVLLSANSIR.A "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 1084.6604 2.06 39377 15228 2 1084.66291 543.3375 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 9.75 3190.6 - 656607 - - - 2.2735 - 1.649 0.273 - 227.4 1 2 0 0.0025 10 0 0 0 1.78E+07 8.68E+06 - - - 2.4527 0.9969 230117_WJC_METTL3_WT_vs_EV_F05.15229.15229.2 0.00757 22-Aug K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.05 39378 15229 2 1287.761944 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3190.7 - 317383 - - - 3.1691 - 1.506 0.251 - 132.3 1 2 0 0.0041 12 0 0 0 4.85E+06 4.61E+06 - - - 1.971 0.9756 230117_WJC_METTL3_WT_vs_EV_F05.15231.15231.2 0.00115 14-Aug R.NIVLYDMR.Q "sp|Q9NV06|DCA13_HUMAN,tr|A0A087WT20|A0A087WT20_HUMAN,tr|A0A087X1F8|A0A087X1F8_HUMAN" 3 1022.5219 0.04 39380 15231 2 1022.530058 512.2682 DDB1- and CUL4-associated factor 13 OS=Homo sapiens OX=9606 GN=DCAF13 PE=1 SV=2 5.84 3191 - 260448 - - - 7.9773 - 1.465 0.38 - 177.6 1 2 0 0.0082 8 0 0 0 5.51E+06 1.45E+08 - - - 2.9968 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.15233.15233.2 0.0268 16-Jul R.YLYLSTMER[166.11].S "sp|Q10570|CPSF1_HUMAN,tr|A0A087X101|A0A087X101_HUMAN" 2 1184.5775 0.64 39382 15233 2 1184.57801 593.296 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6 3191.2 - 213228 - - - 0.417 - 1.23 0.347 - 181.4 1 2 0 0.0005 9 0 0 0 1.87E+06 2.92E+06 - - - 2.2027 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.15236.15236.2 0.0317 20-Oct R.AVAQALEVIPR.T "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1165.6819 999 39385 15236 2 1165.683281 583.8482 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.05 3191.6 - 174927 - - - 1.1779 - 2.292 0.338 - 262.6 1 2 0 0.0014 11 0 0 0 1.50E+06 0.00E+00 - - - 3.7808 0.9915 230117_WJC_METTL3_WT_vs_EV_F05.15240.15240.2 0.705 12-Jul R.IYLYLTK.V "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 912.5321 1.83 39387 15240 2 912.533947 457.2733 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.5 3192.2 - 2.80E+06 - - - 2.0734 - 1.519 0.043 - 175.4 1 2 0 0.0019 7 0 0 0 3.89E+07 2.12E+07 - - - 0.6826 1 230117_WJC_METTL3_WT_vs_EV_F05.15241.15241.2 2.50E-06 14/22 K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 64.24 39388 15241 2 1356.688418 679.3515 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3192.3 - 1.46E+06 - - - -0.0671 - 3.06 0.367 - 908 1 2 0 -0.0001 12 0 0 0 1.15E+07 1.78E+05 - - - 4.6944 0.9938 230117_WJC_METTL3_WT_vs_EV_F05.15242.15242.2 2.67 12-Aug R.IYLYLTK[136.11].V "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 920.5463 1.83 39389 15242 2 920.549026 461.2804 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.5 3192.4 - 1.90E+06 - - - 3.0102 - 1.587 0.105 - 215.5 1 2 0 0.0028 7 0 0 0 3.89E+07 2.12E+07 - - - 1.279 0.9962 230117_WJC_METTL3_WT_vs_EV_F05.15243.15243.2 0.476 12-Aug R.WGGLDLR[166.11].R sp|Q9H7N4|SFR19_HUMAN 1 825.4373 0.88 39390 15243 2 825.439335 413.7259 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.84 3192.6 - 1.22E+06 - - - 2.5175 - 1.408 0.18 - 257 1 2 0 0.0021 7 0 0 0 2.98E+07 3.40E+07 - - - 1.454 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.15244.15244.2 0.102 18-Sep K.IVLLSANSIR[166.11].A "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 1094.6687 2.07 39391 15244 2 1094.671782 548.3416 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 9.75 3192.7 - 1.05E+06 - - - 2.8027 - 1.934 0.345 - 211.4 1 2 0 0.0031 10 0 0 0 1.79E+07 8.68E+06 - - - 3.4293 0.991 230117_WJC_METTL3_WT_vs_EV_F05.15246.15246.2 0.0409 14-Sep R.SVLLEAIR.K sp|Q92558|WASF1_HUMAN 1 899.544 1.22 39393 15246 2 899.54683 450.7793 Wiskott-Aldrich syndrome protein family member 1 OS=Homo sapiens OX=9606 GN=WASF1 PE=1 SV=1 5.72 3192.9 - 738097 - - - 3.1271 - 1.527 0.099 - 224.9 1 2 0 0.0028 8 0 0 0 9.21E+06 7.52E+06 - - - 1.048 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.15251.15251.2 0.00376 16-Aug R.YLYLSTMER.S "sp|Q10570|CPSF1_HUMAN,tr|A0A087X101|A0A087X101_HUMAN" 2 1174.5692 0.65 39398 15251 2 1174.569867 588.2919 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6 3193.6 - 249420 - - - 0.5287 - 1.53 0.354 - 205.5 1 2 0 0.0006 9 0 0 0 1.87E+06 2.85E+06 - - - 2.8858 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.15259.15259.2 0.575 12-Jul R.VTVFDLK.N "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN,tr|C9J544|C9J544_HUMAN" 3 820.4695 1.1 39404 15259 2 820.470877 411.242 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 5.81 3194.6 - 2.00E+06 - - - 1.7332 - 1.474 0.233 - 176.8 1 2 0 0.0014 7 0 0 0 2.85E+07 2.60E+07 - - - 1.9908 1 230117_WJC_METTL3_WT_vs_EV_F05.15261.15261.2 6.41E-05 16-Nov R.PAVLSGYFK.Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 980.5331 1.02 39406 15261 2 980.536933 491.2738 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.01 3194.7 - 1.49E+06 - - - 3.8907 - 2.119 0.458 - 482.4 1 1 0 0.0038 9 0 0 0 9.90E+07 9.71E+07 - - - 4.5951 0.9928 230117_WJC_METTL3_WT_vs_EV_F05.15262.15262.2 1.5 12-Jun K.FLLLQQK[136.11].Y "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 896.5575 2.17 39407 15262 2 896.560089 449.286 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 8.75 3194.8 - 476916 - - - 2.9 - 1.242 0.188 - 94.5 1 2 0 0.0026 7 0 0 0 4.26E+07 1.96E+07 - - - 1.1155 0.9953 230117_WJC_METTL3_WT_vs_EV_F05.15263.15263.2 0.0247 14-Aug R.LLLNYAVR.L "sp|Q92989|CLP1_HUMAN,tr|E9PL17|E9PL17_HUMAN,tr|E9PKV5|E9PKV5_HUMAN" 3 960.5757 -1 39408 15263 2 960.579455 481.2951 Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1 8.75 3194.9 - 410800 - - - 3.9591 - 1.486 0.247 - 179.4 1 2 0 0.0038 8 0 0 0 0.00E+00 0.00E+00 - - - 2.0587 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.15265.15265.2 0.0531 12-May R.WFVTC[160.03]VR.Q "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN,tr|A0A140T954|A0A140T954_HUMAN" 3 966.4746 0.67 39410 15265 2 966.476936 484.2446 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 8.25 3195.2 - 263224 - - - 2.4605 - 1.052 0.35 - 68 1 2 0 0.0024 7 0 0 0 5.48E+06 8.22E+06 - - - 1.786 1 230117_WJC_METTL3_WT_vs_EV_F05.15266.15266.2 1.07E-05 18-Sep R.LITLEEEMTK.Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1205.6213 2.7 39411 15266 2 1205.627805 603.8179 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3195.3 - 219816 - - - 5.3616 - 2.009 0.509 - 213.4 1 2 0 0.0065 10 0 0 0 1.86E+07 6.89E+06 - - - 4.7458 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.15273.15273.2 0.00632 14-Jul K.NVPYVFVR.S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 992.5444 1.03 39416 15273 2 992.548633 497.2795 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3196.3 - 4.53E+06 - - - 4.3142 - 1.425 0.41 - 206.3 1 2 0 0.0043 8 0 0 0 1.35E+08 1.30E+08 - - - 3.1361 0.9869 230117_WJC_METTL3_WT_vs_EV_F05.15274.15274.2 0.714 12-Jun R.WGGLDLR.R sp|Q9H7N4|SFR19_HUMAN 1 815.429 0.67 39417 15274 2 815.432113 408.7218 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.84 3196.4 - 2.34E+06 - - - 3.8336 - 1.29 0.17 - 195.2 1 2 0 0.0031 7 0 0 0 3.00E+07 4.49E+07 - - - 1.1025 0.9926 230117_WJC_METTL3_WT_vs_EV_F05.15276.15276.2 0.0544 12-Jul K.SEFVILR.D "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 862.4913 0.95 39419 15276 2 862.494661 432.2529 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 5.72 3196.5 - 1.06E+06 - - - 3.9513 - 1.51 0.176 - 227.5 1 2 0 0.0034 7 0 0 0 3.81E+07 4.02E+07 - - - 1.6457 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.15277.15277.2 0.0417 14-Aug K.LGFESIYK.L "sp|P49643|PRI2_HUMAN,tr|A0A5F9ZHU7|A0A5F9ZHU7_HUMAN" 2 955.5015 2.01 39420 15277 2 955.503852 478.758 DNA primase large subunit OS=Homo sapiens OX=9606 GN=PRIM2 PE=1 SV=2 6 3196.6 - 1.03E+06 - - - 2.4783 - 1.687 0.203 - 142.5 1 2 0 0.0024 8 0 0 0 1.27E+07 6.30E+06 - - - 2.1168 0.9764 230117_WJC_METTL3_WT_vs_EV_F05.15279.15279.2 0.627 12-Jul K.LQQLWLK.A "sp|Q9NPC8|SIX2_HUMAN,sp|Q15475|SIX1_HUMAN" 2 927.5542 2.05 39422 15279 2 927.557143 464.7844 Homeobox protein SIX2 OS=Homo sapiens OX=9606 GN=SIX2 PE=1 SV=1 8.75 3196.7 - 902564 - - - 3.1858 - 1.366 0.046 - 110.8 1 2 0 0.003 7 0 0 0 1.58E+07 7.69E+06 - - - 0.3681 0.9529 230117_WJC_METTL3_WT_vs_EV_F05.15285.15285.2 1.89 12-Jun R.LIMQYLK.E sp|Q2TAY7|SMU1_HUMAN 1 907.5201 0.95 39426 15285 2 907.524033 454.7673 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.59 3197.4 - 652038 - - - 4.3217 - 1.186 0.129 - 91.4 2 2 0 0.0039 7 0 0 0 3.81E+07 4.03E+07 - - - 0.3986 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.15287.15287.2 0.137 16-Aug R.ALVQSLLAK.E sp|Q9NX46|ADPRS_HUMAN 1 941.591 3.09 39428 15287 2 941.595139 471.8028 ADP-ribose glycohydrolase ARH3 OS=Homo sapiens OX=9606 GN=ADPRS PE=1 SV=1 8.8 3197.7 - 148594 - - - 4.4308 - 1.579 0.291 - 120.1 1 2 0 0.0042 9 0 0 0 9.21E+06 2.98E+06 - - - 2.5105 0.9759 230117_WJC_METTL3_WT_vs_EV_F05.15291.15291.2 0.89 12-Jun R.LIMQYLK[136.11].E sp|Q2TAY7|SMU1_HUMAN 1 915.5343 0.95 39430 15291 2 915.536797 458.7744 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.59 3198.1 - 1.19E+06 - - - 2.7154 - 1.093 0.114 - 93.6 1 2 0 0.0025 7 0 0 0 3.80E+07 4.02E+07 - - - 0.164 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.15293.15293.2 0.115 18-Sep K.LVIIEGDLER.T "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1155.6499 1.3 39432 15293 2 1155.653674 578.8322 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.14 3198.4 - 292257 - - - 3.2319 - 1.785 0.311 - 249.8 1 2 0 0.0037 10 0 0 0 1.79E+07 1.38E+07 - - - 2.9542 0.8696 230117_WJC_METTL3_WT_vs_EV_F05.15294.15294.2 0.0214 16-Aug V.ILQTLPQLR.L "sp|Q9C099|LRCC1_HUMAN,sp|Q5T4S7|UBR4_HUMAN,tr|A0A0A0MSW0|A0A0A0MSW0_HUMAN,tr|X6RE05|X6RE05_HUMAN" 4 1080.6655 0.68 39433 15294 2 1080.667947 541.34 Leucine-rich repeat and coiled-coil domain-containing protein 1 OS=Homo sapiens OX=9606 GN=LRRCC1 PE=1 SV=2 9.75 3198.5 - 243644 - - - 2.2375 - 1.608 0.208 - 158.7 1 1 0 0.0024 9 0 0 0 1.04E+07 1.52E+07 - - - 1.9507 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.15301.15301.2 6.86E-05 18-Oct R.LITLEEEMTK[136.11].Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1213.6355 2.7 39438 15301 2 1213.639937 607.825 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3199.4 - 549735 - - - 3.6222 - 1.68 0.509 - 284.3 1 2 0 0.0044 10 0 0 0 1.86E+07 6.89E+06 - - - 4.2472 1 230117_WJC_METTL3_WT_vs_EV_F05.15312.15312.2 0.000188 16-Nov K.LGEWVGLC[160.03]K.L sp|P25398|RS12_HUMAN 1 1060.5376 2.24 39446 15312 2 1060.540901 531.2761 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3200.8 - 6.55E+06 - - - 3.1578 - 2.218 0.455 - 484.5 1 2 0 0.0033 9 0 0 0 2.04E+08 9.10E+07 - - - 4.7052 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.15314.15314.2 0.208 16-Oct K.LGEWVGLC[160.03]K[136.11].L sp|P25398|RS12_HUMAN 1 1068.5518 2.24 39448 15314 2 1068.555057 535.2832 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3201 - 3.50E+06 - - - 3.093 - 1.928 0.35 - 332.4 1 2 0 0.0033 9 0 0 0 2.04E+08 9.10E+07 - - - 3.5243 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.15325.15325.2 0.01 18-Jul K.VLFTGVVDAR[166.11].G sp|Q14676|MDC1_HUMAN 1 1085.6109 2.47 39458 15325 2 1085.613949 543.8127 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 5.81 3202.3 - 314381 - - - 2.8408 - 1.487 0.293 - 126.3 1 2 0 0.0031 10 0 0 0 2.88E+07 1.16E+07 - - - 2.3116 0.9861 230117_WJC_METTL3_WT_vs_EV_F05.15326.15326.2 0.00749 20-Oct R.LVEMASSLAIR.E "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1188.6536 11.87 39459 15326 2 1188.66229 595.3341 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3202.4 - 157213 - - - 7.2738 - 1.793 0.367 - 233.1 1 2 0 0.0086 11 0 0 0 5.44E+06 4.58E+05 - - - 3.3285 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15329.15329.2 0.13 18-Aug K.SYLYPSTLVR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1207.6476 0.36 39460 15329 2 1207.650265 604.8311 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 3202.8 - 2.71E+06 - - - 2.1703 - 1.808 0.34 - 240.1 1 2 0 0.0026 10 0 0 0 3.40E+08 9.45E+08 - - - 3.2045 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.15331.15331.2 0.357 12-Aug K.TSILVFK[136.11].D sp|Q9BRS2|RIOK1_HUMAN 1 814.5044 0.63 39462 15331 2 814.507268 408.2595 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 8.41 3203.1 - 782198 - - - 3.5322 - 1.878 0.316 - 256.6 1 2 0 0.0029 7 0 0 0 3.35E+07 5.29E+07 - - - 3.3709 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.15332.15332.2 0.118 18-Oct K.SYLYPSTLVR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1197.6394 0.36 39463 15332 2 1197.641944 599.827 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 3203.2 - 736409 - - - 2.1459 - 1.951 0.345 - 411.3 1 2 0 0.0026 10 0 0 0 3.40E+08 9.45E+08 - - - 3.4539 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.15337.15337.2 0.0921 18-Jul K.LVIIEGDLER[166.11].T "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1165.6582 1.28 39466 15337 2 1165.659658 583.8364 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.14 3203.9 - 522732 - - - 1.2431 - 1.413 0.197 - 121.8 1 2 0 0.0014 10 0 0 0 1.79E+07 1.40E+07 - - - 1.4606 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.15357.15357.2 0.777 14-Jul K.ILEDSFLK.S sp|Q9Y6X8|ZHX2_HUMAN 1 963.5277 1.77 39480 15357 2 963.529368 482.7711 Zinc fingers and homeoboxes protein 2 OS=Homo sapiens OX=9606 GN=ZHX2 PE=1 SV=1 4.37 3206.4 - 331033 - - - 1.7332 - 1.268 0.194 - 91 1 2 0 0.0017 8 0 0 0 1.75E+07 9.92E+06 - - - 1.1895 0.9786 230117_WJC_METTL3_WT_vs_EV_F05.15359.15359.2 3.19 16-May R.LLDEYNLVR.S "sp|P46531|NOTC1_HUMAN,tr|A0A7P0T8U6|A0A7P0T8U6_HUMAN,tr|A0A7P0TA56|A0A7P0TA56_HUMAN,tr|A0A7P0TB20|A0A7P0TB20_HUMAN,tr|A0A7P0T8W1|A0A7P0T8W1_HUMAN" 5 1133.6081 2.2 39482 15359 2 1133.610571 567.8113 Neurogenic locus notch homolog protein 1 OS=Homo sapiens OX=9606 GN=NOTCH1 PE=1 SV=4 4.37 3206.6 - 159603 - - - 2.2027 - 1.105 0.101 - 54.4 1 2 0 0.0025 9 0 0 0 4.76E+06 2.16E+06 - - - 0.0751 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.15364.15364.2 0.316 12-Jul K.LC[160.03]TFILK[136.11].N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 901.5187 1.15 39485 15364 2 901.519984 451.7666 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3207.3 - 437614 - - - 1.4675 - 1.31 0.187 - 108.9 1 2 0 0.0013 7 0 0 0 2.69E+07 2.33E+07 - - - 1.2774 0.9963 230117_WJC_METTL3_WT_vs_EV_F05.15367.15367.2 0.0238 12-Aug K.LC[160.03]TFILK.N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 893.5045 1.17 39486 15367 2 893.506443 447.7595 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3207.7 - 997722 - - - 2.2182 - 1.375 0.178 - 147.9 1 2 0 0.002 7 0 0 0 2.89E+07 2.47E+07 - - - 1.3641 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.15368.15368.2 0.0525 22-Nov K.AVASAAAALVLK.A sp|Q9Y490|TLN1_HUMAN 1 1083.6652 1.09 39487 15368 2 1083.668504 542.8399 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.8 3207.8 - 500955 - - - 3.0535 - 1.82 0.377 - 269.9 1 2 0 0.0033 12 0 0 0 2.46E+07 2.25E+07 - - - 3.4001 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.15372.15372.2 0.0113 13/20 K.IGLFGGAGVGK.T "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 974.5549 3.15 39489 15372 2 974.555976 488.2847 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 8.75 3208.3 - 1.23E+06 - - - 1.0877 - 2.282 0.36 - 353.8 1 2 0 0.0011 11 0 0 0 5.84E+08 1.86E+08 - - - 3.9316 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.15379.15379.2 0.00634 22-Dec R.EHALLAYTLGVK.Q "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 11 1313.7343 8.39 39494 15379 2 1313.735465 657.8744 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.85 3209.3 - 226325 - - - 0.8586 - 1.603 0.308 - 192.3 1 2 0 0.0011 12 0 0 0 6.64E+06 7.91E+05 - - - 2.5571 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15381.15381.2 0.00239 20-Dec K.IGLFGGAGVGK[136.11].T "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 982.5691 2.91 39496 15381 2 982.571977 492.2918 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 8.75 3209.4 - 1.17E+06 - - - 2.9118 - 2.516 0.295 - 231.4 1 2 0 0.0029 11 0 0 0 5.37E+08 1.85E+08 - - - 3.715 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.15391.15391.2 0.274 14-Aug R.IGQFVFAR.D sp|Q9NRN7|ADPPT_HUMAN 1 936.5181 5.98 39502 15391 2 936.51989 469.2663 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2 9.75 3210.6 - 5.24E+06 - - - 1.8718 - 1.79 0.268 - 191.4 1 2 0 0.0018 8 0 0 0 1.08E+08 1.81E+07 - - - 2.7758 0.9598 230117_WJC_METTL3_WT_vs_EV_F05.15392.15392.2 0.307 12-Jul R.ALTALFK.E "sp|Q9UBB4|ATX10_HUMAN,tr|A0A1W2PQD2|A0A1W2PQD2_HUMAN" 2 762.464 1.64 39503 15392 2 762.468607 382.2393 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 8.8 3210.7 - 1.03E+06 - - - 6.0737 - 1.395 0.178 - 195 1 2 0 0.0046 7 0 0 0 3.93E+07 2.39E+07 - - - 1.409 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.15405.15405.2 0.522 12-Jun R.ALTALFK[136.11].E "sp|Q9UBB4|ATX10_HUMAN,tr|A0A1W2PQD2|A0A1W2PQD2_HUMAN" 2 770.4782 1.64 39511 15405 2 770.479461 386.2464 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 8.8 3212.2 - 1.07E+06 - - - 1.6678 - 1.193 0.207 - 120.4 1 2 0 0.0013 7 0 0 0 3.94E+07 2.40E+07 - - - 1.1287 0.9882 230117_WJC_METTL3_WT_vs_EV_F05.15407.15407.2 0.416 12-Jun R.FLVTVIK.D "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 818.5266 1.46 39513 15407 2 818.529964 410.2706 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3212.5 - 1.74E+06 - - - 4.1391 - 1.378 0.176 - 126.2 1 2 0 0.0034 7 0 0 0 8.71E+07 5.98E+07 - - - 1.3558 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.15422.15422.2 0.0573 14-Aug R.TVEDVFLR[166.11].K sp|Q96EL2|RT24_HUMAN 1 987.5265 0.97 39524 15422 2 987.52885 494.7705 "28S ribosomal protein S24, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS24 PE=1 SV=1" 4.37 3214.3 - 590466 - - - 2.4141 - 1.39 0.254 - 222.7 1 2 0 0.0024 8 0 0 0 3.02E+07 3.12E+07 - - - 1.9095 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.15426.15426.2 0.00503 16-Aug R.AATLMMLGR.F "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PR93|A0A6I8PR93_HUMAN,tr|K7ESP1|K7ESP1_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|K7EJE9|K7EJE9_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|K7ELJ8|K7ELJ8_HUMAN,tr|K7EN19|K7EN19_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EJL5|K7EJL5_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|K7EJV7|K7EJV7_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 21 962.5041 0.9 39526 15426 2 962.507861 482.2593 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 9.79 3214.8 - 1.11E+06 - - - 3.8628 - 1.621 0.385 - 192.3 1 2 0 0.0037 9 0 0 0 4.22E+07 4.67E+07 - - - 3.2809 0.9647 230117_WJC_METTL3_WT_vs_EV_F05.15427.15427.2 2.76 12-Jul R.LILEALK[136.11].Q "sp|Q8IX18|DHX40_HUMAN,sp|Q6TDP4|KLH17_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|D6RJB0|D6RJB0_HUMAN,tr|H0Y9K3|H0Y9K3_HUMAN,tr|A0A3B3ISF8|A0A3B3ISF8_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN,tr|Q0VGE6|Q0VGE6_HUMAN,tr|J3QLT4|J3QLT4_HUMAN,tr|A0A3B3IT29|A0A3B3IT29_HUMAN,tr|D6R9W6|D6R9W6_HUMAN,tr|G3V0E9|G3V0E9_HUMAN" 12 806.5357 1.27 39527 15427 2 806.538451 404.2751 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 6 3214.9 - 605563 - - - 3.422 - 1.35 0.027 - 126.4 1 2 0 0.0028 7 0 0 0 3.08E+07 2.43E+07 - - - 0.1905 0.9944 230117_WJC_METTL3_WT_vs_EV_F05.15430.15430.2 0.478 12-Aug R.C[160.03]ILPFDK[136.11].E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 899.4666 1.33 39528 15430 2 899.468249 450.7406 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.83 3215.4 - 968168 - - - 1.8055 - 1.268 0.153 - 299.1 1 2 0 0.0016 7 0 0 0 1.33E+08 9.94E+07 - - - 0.9229 0.9907 230117_WJC_METTL3_WT_vs_EV_F05.15432.15432.2 4.11 12-Jul R.LWISVAR[166.11].Y sp|Q15029|U5S1_HUMAN 1 853.5049 1.61 39529 15432 2 853.506654 427.7597 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 9.75 3215.6 - 3.52E+06 - - - 2.0047 - 1.302 0.098 - 220.5 1 2 0 0.0017 7 0 0 0 1.46E+08 9.05E+07 - - - 0.6005 0.999 230117_WJC_METTL3_WT_vs_EV_F05.15437.15437.2 0.0124 12-Jun K.YIQELWR[166.11].K "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1016.5319 0.74 39532 15437 2 1016.532276 509.2732 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 6 3216.2 - 5.78E+06 - - - 0.3837 - 1.425 0.325 - 159.5 1 2 0 0.0004 7 0 0 0 1.17E+08 1.58E+08 - - - 2.5635 0.9879 230117_WJC_METTL3_WT_vs_EV_F05.15438.15438.2 3.17 12-Jul R.C[160.03]ILPFDK.E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 891.4524 1.36 39533 15438 2 891.453863 446.7335 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.83 3216.2 - 1.22E+06 - - - 1.6131 - 1.246 0.083 - 189.3 1 2 0 0.0014 7 0 0 0 1.35E+08 9.94E+07 - - - 0.3505 0.9935 230117_WJC_METTL3_WT_vs_EV_F05.15441.15441.2 0.114 18-Jul R.LGTVLPVIEK[136.11].E sp|O75691|UTP20_HUMAN 1 1075.6732 0.99 39534 15441 2 1075.674458 538.8439 Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3 6 3216.6 - 207798 - - - 1.1258 - 1.336 0.126 - 92.8 1 2 0 0.0012 10 0 0 0 9.71E+06 9.84E+06 - - - 0.7798 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.15443.15443.2 1.27 14-Aug R.GLVVPVIR[166.11].N sp|P36957|ODO2_HUMAN 1 861.5675 0.93 39535 15443 2 861.568782 431.791 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3216.8 - 743059 - - - 1.4381 - 1.551 0.222 - 281.6 1 2 0 0.0012 8 0 0 0 7.20E+07 7.77E+07 - - - 2.004 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15444.15444.2 0.0114 14-Aug R.LLEC[160.03]YFTR[166.11].S "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1110.5407 1.8 39536 15444 2 1110.542411 556.2776 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.99 3216.9 - 364586 - - - 1.5083 - 1.492 0.378 - 154.5 1 2 0 0.0017 8 0 0 0 2.03E+07 1.12E+07 - - - 3.0391 0.9887 230117_WJC_METTL3_WT_vs_EV_F05.15450.15450.2 0.438 14-May K.VFPLAEYR.T sp|Q86T24|KAISO_HUMAN 1 993.5284 4.48 39540 15450 2 993.527923 497.7715 Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2 5.97 3217.7 - 704460 - - - -0.4469 - 1.056 0.222 - 84.5 1 2 0 -0.0004 8 0 0 0 1.88E+07 4.19E+06 - - - 0.8449 0.9832 230117_WJC_METTL3_WT_vs_EV_F05.15452.15452.2 0.431 14-Jul R.LLFGPTVR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 911.5468 0.8 39541 15452 2 911.54774 456.7807 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3217.9 - 1.09E+06 - - - 1.0224 - 1.249 0.057 - 116.6 1 2 0 0.0009 8 0 0 0 5.70E+07 7.10E+07 - - - 0.1323 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.15458.15458.2 0.0234 16-Aug R.LIVNVNDLR[166.11].R sp|P25205|MCM3_HUMAN 1 1064.6218 5.68 39545 15458 2 1064.623257 533.3182 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.84 3218.7 - 1.03E+06 - - - 1.4024 - 1.651 0.271 - 207.3 1 2 0 0.0015 9 0 0 0 1.07E+08 1.89E+07 - - - 2.4927 0.9923 230117_WJC_METTL3_WT_vs_EV_F05.15468.15468.2 0.324 22-Sep K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.18 39553 15468 2 1277.751938 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3219.8 - 939818 - - - 1.8353 - 1.351 0.118 - 127.8 1 2 0 0.0023 12 0 0 0 2.41E+07 2.05E+07 - - - 0.7034 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.15471.15471.2 0.112 18-Sep K.ALVLTEIGPK.R sp|O14732|IMPA2_HUMAN 1 1039.6277 999 39556 15471 2 1039.628434 520.8211 Inositol monophosphatase 2 OS=Homo sapiens OX=9606 GN=IMPA2 PE=1 SV=1 6.05 3220.2 - 516417 - - - 0.6608 - 1.662 0.288 - 246 1 2 0 0.0007 10 0 0 0 9.89E+06 0.00E+00 - - - 2.586 0.9897 230117_WJC_METTL3_WT_vs_EV_F05.15481.15481.2 0.0834 22-Jul K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.18 39564 15481 2 1287.758813 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3221.2 - 827790 - - - 0.7377 - 1.448 0.067 - 90.7 1 2 0 0.0009 12 0 0 0 2.51E+07 2.12E+07 - - - 0.5096 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.15482.15482.2 0.00769 16-Aug K.LITWSPVC[160.03]R.N "sp|P07203|GPX1_HUMAN,tr|A0A2R8Y6B6|A0A2R8Y6B6_HUMAN" 2 1130.5907 2.35 39565 15482 2 1130.59609 566.3026 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 8.25 3221.4 - 523207 - - - 4.8116 - 1.738 0.372 - 221.4 1 2 0 0.0054 9 0 0 0 1.04E+07 4.44E+06 - - - 3.386 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.15486.15486.2 0.00199 14-Aug R.GLVVPVIR.N sp|P36957|ODO2_HUMAN 1 851.5593 0.93 39567 15486 2 851.560525 426.7869 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3221.8 - 1.96E+06 - - - 1.4702 - 1.698 0.195 - 364.4 1 2 0 0.0013 8 0 0 0 7.20E+07 7.77E+07 - - - 2.0777 0.9818 230117_WJC_METTL3_WT_vs_EV_F05.15489.15489.2 0.871 16-Jul K.FVPLLPGNR[166.11].S sp|P78527|PRKDC_HUMAN 1 1021.5948 1.03 39570 15489 2 1021.596136 511.8047 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3222.1 - 772499 - - - 1.2872 - 1.235 0.056 - 169.7 1 2 0 0.0013 9 0 0 0 4.17E+07 4.06E+07 - - - 0.0648 0.9947 230117_WJC_METTL3_WT_vs_EV_F05.15490.15490.2 0.333 16-Jul K.FVPLLPGNR.S sp|P78527|PRKDC_HUMAN 1 1011.5866 1.03 39571 15490 2 1011.588094 506.8006 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3222.2 - 607359 - - - 1.5253 - 1.262 0.166 - 180 1 2 0 0.0015 9 0 0 0 4.17E+07 4.06E+07 - - - 0.9398 0.8967 230117_WJC_METTL3_WT_vs_EV_F05.15494.15494.2 0.0155 14-Aug K.YYVLNALK.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 982.5488 2.24 39573 15494 2 982.545113 492.2817 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.5 3222.7 - 2.68E+06 - - - -3.7199 - 1.175 0.155 - 140.3 1 2 0 -0.0037 8 0 0 0 1.32E+08 5.89E+07 - - - 0.6711 0.8935 230117_WJC_METTL3_WT_vs_EV_F05.15495.15495.2 4.34 16-May K.ILLLEAGPK.K "sp|Q9Y2Z9|COQ6_HUMAN,tr|G3V4A6|G3V4A6_HUMAN,tr|G3V2L5|G3V2L5_HUMAN,tr|G3V434|G3V434_HUMAN" 4 952.5957 1.61 39574 15495 2 952.599198 477.3051 "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial OS=Homo sapiens OX=9606 GN=COQ6 PE=1 SV=2" 6 3222.8 - 2.07E+06 - - - 3.6532 - 0.888 0.113 - 60.9 1 2 0 0.0035 9 0 0 0 5.97E+07 3.70E+07 - - - -0.4691 0.9957 230117_WJC_METTL3_WT_vs_EV_F05.15496.15496.2 0.64 14-Jul R.LLPEQLIK[136.11].E "sp|Q92621|NU205_HUMAN,sp|Q8TBZ9|TEX47_HUMAN" 2 960.6099 1.53 39575 15496 2 960.611303 481.3122 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 6 3222.8 - 1.00E+06 - - - 1.4418 - 1.018 0.27 - 101.7 1 2 0 0.0014 8 0 0 0 5.97E+07 3.91E+07 - - - 1.0886 0.998 230117_WJC_METTL3_WT_vs_EV_F05.15498.15498.2 0.299 14-May K.FLILNPSK.R "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 930.5539 0.8 39577 15498 2 930.555064 466.2842 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 8.75 3223.1 - 448122 - - - 1.3003 - 1.247 0.273 - 67.6 1 2 0 0.0012 8 0 0 0 1.40E+07 1.75E+07 - - - 1.7227 0.998 230117_WJC_METTL3_WT_vs_EV_F05.15499.15499.2 0.077 16-Aug K.LLPDTILEK[136.11].L "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1048.626 0.71 39578 15499 2 1048.628843 525.3203 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 4.37 3223.2 - 429934 - - - 2.7474 - 1.548 0.252 - 163.6 1 2 0 0.0029 9 0 0 0 8.34E+07 1.18E+08 - - - 2.1655 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15500.15500.2 0.000925 22-Oct K.NYIQGINLVQAK.K "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1359.7511 3.07 39579 15500 2 1359.752118 680.8828 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 8.59 3223.3 - 253414 - - - 0.7854 - 1.512 0.401 - 162 1 2 0 0.0011 12 0 0 0 4.83E+06 1.57E+06 - - - 3.0903 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.15503.15503.2 0.256 12-Jun M.GVPAFFR.W sp|Q9H0D6|XRN2_HUMAN 1 792.4283 0.83 39581 15503 2 792.429367 397.2214 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 3223.7 - 4.18E+06 - - - 1.3982 - 1.124 0.281 - 174.2 1 2 0 0.0011 7 0 0 0 1.89E+08 2.26E+08 - - - 1.4865 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15507.15507.2 0.0131 14-Aug K.YYVLNALK[136.11].H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 990.563 2.34 39584 15507 2 990.564208 496.2888 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.5 3224.1 - 3.55E+06 - - - 1.2518 - 1.264 0.452 - 156.5 1 2 0 0.0012 8 0 0 0 1.37E+08 5.86E+07 - - - 3.0857 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.15512.15512.2 0.248 14-Jul R.LLFGPTVR.L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 901.5385 0.68 39587 15512 2 901.538823 451.7765 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3224.7 - 4.05E+06 - - - 0.3161 - 1.347 0.25 - 136.3 1 2 0 0.0003 8 0 0 0 5.71E+07 8.37E+07 - - - 1.7858 0.999 230117_WJC_METTL3_WT_vs_EV_F05.15514.15514.2 8.11E-05 22-Oct R.LLETC[160.03]SIALVGK.Y "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN,tr|A0A3B3ISY3|A0A3B3ISY3_HUMAN" 7 1302.7217 3.75 39589 15514 2 1302.727097 652.3681 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 5.99 3225 - 337053 - - - 4.1244 - 1.908 0.497 - 278.1 1 2 0 0.0054 12 0 0 0 4.51E+06 1.20E+06 - - - 4.41 1 230117_WJC_METTL3_WT_vs_EV_F05.15519.15519.2 3.50E-07 16-Oct K.YMTDGMLLR[166.11].E "sp|Q14562|DHX8_HUMAN,sp|O60231|DHX16_HUMAN,sp|O43143|DHX15_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|F5H658|F5H658_HUMAN" 5 1108.5285 1.13 39592 15519 2 1108.531054 555.2715 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 5.84 3225.6 - 895876 - - - 2.3427 - 1.983 0.658 - 345.3 1 2 0 0.0026 9 0 0 0 2.57E+07 2.27E+07 - - - 5.8808 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.15532.15532.2 0.000457 18-Nov K.LLANMVYQYK.G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1241.6478 1.66 39602 15532 2 1241.649984 621.8312 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3227.2 - 258101 - - - 1.7348 - 1.865 0.42 - 347.7 1 2 0 0.0022 10 0 0 0 1.94E+07 1.17E+07 - - - 3.8822 0.996 230117_WJC_METTL3_WT_vs_EV_F05.15534.15534.2 0.195 12-Jun M.GVPAFFR[166.11].W sp|Q9H0D6|XRN2_HUMAN 1 802.4365 0.83 39603 15534 2 802.437627 402.2255 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 3227.4 - 9.32E+06 - - - 1.3683 - 1.167 0.218 - 186.7 1 2 0 0.0011 7 0 0 0 1.89E+08 2.27E+08 - - - 1.1401 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15536.15536.2 0.0628 18-Sep K.LLANMVYQYK[136.11].G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1249.662 1.66 39604 15536 2 1249.662629 625.8383 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3227.6 - 255736 - - - 0.4793 - 1.814 0.351 - 278.1 1 2 0 0.0006 10 0 0 0 1.94E+07 1.17E+07 - - - 3.2956 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.15541.15541.2 0.0124 18-Oct K.LIESAEELIR.D "sp|Q13217|DNJC3_HUMAN,tr|X6R9L0|X6R9L0_HUMAN" 2 1171.6449 1.76 39609 15541 2 1171.648336 586.8297 DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1 4.25 3228.2 - 360941 - - - 2.9727 - 1.698 0.231 - 239.1 1 2 0 0.0035 10 0 0 0 9.64E+06 5.49E+06 - - - 2.2239 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.15549.15549.2 0.00443 16-Sep R.LFEGNALLR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1031.5764 0.88 39615 15549 2 1031.578527 516.7955 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3229.1 - 2.11E+06 - - - 2.0813 - 1.808 0.404 - 285.6 1 2 0 0.0021 9 0 0 0 1.13E+09 1.28E+09 - - - 3.7376 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.15550.15550.2 0.00892 16-Sep R.VLGMTLIQK.C sp|Q04760|LGUL_HUMAN 1 1001.5943 1.25 39616 15550 2 1001.596925 501.8044 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3229.2 - 868321 - - - 2.5829 - 1.917 0.141 - 182.4 1 2 0 0.0026 9 0 0 0 2.92E+07 2.34E+07 - - - 1.9643 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.15552.15552.2 0.006 14-Jul R.AFLLDPDR.C sp|Q9BTY7|HGH1_HUMAN 1 945.492 0.98 39618 15552 2 945.490613 473.7533 Protein HGH1 homolog OS=Homo sapiens OX=9606 GN=HGH1 PE=1 SV=1 4.21 3229.5 - 217027 - - - -1.4479 - 1.52 0.299 - 159.7 1 2 0 -0.0014 8 0 0 0 8.38E+06 8.53E+06 - - - 2.5118 1 230117_WJC_METTL3_WT_vs_EV_F05.15554.15554.2 8.73E-06 20-Nov K.WEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1215.6288 0.84 39619 15554 2 1215.63185 608.8217 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3229.7 - 357800 - - - 2.5016 - 1.916 0.525 - 256.3 1 2 0 0.003 11 0 0 0 4.23E+07 5.04E+07 - - - 4.6767 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.15556.15556.2 0.000653 16-Jul R.LFEGNALLR[166.11].R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1041.5847 0.88 39620 15556 2 1041.583714 521.7996 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3229.9 - 1.34E+07 - - - -0.8986 - 1.596 0.403 - 125.9 1 2 0 -0.0009 9 0 0 0 1.13E+09 1.28E+09 - - - 3.3698 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.15557.15557.2 0.000135 14-Sep K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 1.74 39621 15557 2 895.48241 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3230 - 2.36E+06 - - - 2.296 - 1.87 0.46 - 203.6 1 2 0 0.0021 8 0 0 0 2.59E+09 1.49E+09 - - - 4.3257 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.15558.15558.2 0.0536 16-Aug R.VLGMTLIQK[136.11].C sp|Q04760|LGUL_HUMAN 1 1009.6085 1.25 39622 15558 2 1009.611986 505.8115 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3230.1 - 2.50E+06 - - - 3.4152 - 1.577 0.28 - 160.2 1 2 0 0.0034 9 0 0 0 2.92E+07 2.33E+07 - - - 2.4259 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.15560.15560.2 0.00287 16-Aug K.YMTDGMLLR.E "sp|Q14562|DHX8_HUMAN,sp|O60231|DHX16_HUMAN,sp|O43143|DHX15_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|F5H658|F5H658_HUMAN" 5 1098.5202 1.15 39624 15560 2 1098.523592 550.2674 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 5.84 3230.2 - 1.48E+06 - - - 3.0996 - 1.402 0.366 - 182.7 1 2 0 0.0034 9 0 0 0 2.56E+07 2.23E+07 - - - 2.7208 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.15561.15561.2 2.97 14-Sep R.SLVSGLIR[166.11].L sp|Q92616|GCN1_HUMAN 1 853.5261 1.1 39625 15561 2 853.529069 427.7703 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.47 3230.3 - 1.46E+06 - - - 3.5113 - 1.549 0.242 - 303.3 1 2 0 0.003 8 0 0 0 5.05E+07 4.58E+07 - - - 2.1473 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.15564.15564.2 0.036 18-Aug K.LIESAEELIR[166.11].D "sp|Q13217|DNJC3_HUMAN,tr|X6R9L0|X6R9L0_HUMAN" 2 1181.6531 1.76 39628 15564 2 1181.656872 591.8338 DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1 4.25 3230.7 - 907279 - - - 3.1727 - 1.866 0.229 - 163.1 1 2 0 0.0037 10 0 0 0 9.64E+06 5.49E+06 - - - 2.4724 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.15570.15570.2 0.338 14-Aug K.MLLSLPEK.V "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 929.5256 1.12 39632 15570 2 929.528817 465.7701 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 5.75 3231.5 - 833791 - - - 3.4717 - 1.715 0.227 - 241.3 1 2 0 0.0032 8 0 0 0 1.62E+07 1.44E+07 - - - 2.3435 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.15575.15575.2 0.0131 18-Aug K.LNC[160.03]FLEQDLK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1286.642 0.12 39637 15575 2 1286.645891 644.3283 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 3232 - 582869 - - - 3.0063 - 1.505 0.257 - 115.1 1 2 0 0.0039 10 0 0 0 2.57E+06 2.15E+07 - - - 2.0791 0.9044 230117_WJC_METTL3_WT_vs_EV_F05.15576.15576.2 0.0921 12-Aug L.FGDLLLK[136.11].Q "sp|Q15147|PLCB4_HUMAN,sp|Q6P2Q9|PRP8_HUMAN,tr|A0A7P0MRI8|A0A7P0MRI8_HUMAN" 3 812.4887 1.25 39638 15576 2 812.49016 407.2516 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4 PE=1 SV=3" 5.84 3232.1 - 486739 - - - 1.7465 - 1.666 0.2 - 137.3 1 1 0 0.0014 7 0 0 0 1.48E+08 1.18E+08 - - - 2.1351 0.9843 230117_WJC_METTL3_WT_vs_EV_F05.15578.15578.2 2.23 12-May R.GFFNGLR[166.11].T "sp|Q9Y394|DHRS7_HUMAN,tr|H0YJ66|H0YJ66_HUMAN,tr|H0YJE4|H0YJE4_HUMAN,tr|H0YJR8|H0YJR8_HUMAN" 4 819.4267 1.33 39640 15578 2 819.429013 410.7206 Dehydrogenase\reductase SDR family member 7 OS=Homo sapiens OX=9606 GN=DHRS7 PE=1 SV=1 9.75 3232.4 - 167647 - - - 2.8312 - 1.132 0.145 - 89.5 1 2 0 0.0023 7 0 0 0 6.66E+06 5.01E+06 - - - 0.5041 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.15581.15581.2 0.0948 14-Sep K.VFNLGVYR[166.11].R "sp|O60825|F262_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN" 2 976.537 0.56 39641 15581 2 976.538464 489.2758 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 8.72 3232.8 - 967240 - - - 1.5289 - 1.729 0.195 - 339.2 1 2 0 0.0015 8 0 0 0 2.67E+07 4.78E+07 - - - 2.1322 1 230117_WJC_METTL3_WT_vs_EV_F05.15583.15583.2 0.000464 20-Nov R.VIGTLLGTVDK[136.11].H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1122.674 1.13 39643 15583 2 1122.67755 562.3443 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3233 - 634817 - - - 3.1844 - 2.323 0.484 - 257.8 1 2 0 0.0036 11 0 0 0 1.04E+08 9.15E+07 - - - 4.8948 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.15584.15584.2 0.00154 20-Nov R.VIGTLLGTVDK.H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1114.6598 1.13 39644 15584 2 1114.664819 558.3372 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3233.1 - 517059 - - - 4.5251 - 1.815 0.326 - 216.7 1 2 0 0.005 11 0 0 0 1.03E+08 9.14E+07 - - - 3.0598 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.15587.15587.2 0.135 14-Jun R.IAVPVLVR.D sp|P52952|NKX25_HUMAN 1 865.5749 2.11 39647 15587 2 865.576041 433.7947 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 9.75 3233.5 - 283946 - - - 1.2916 - 1.421 0.292 - 134.2 1 2 0 0.0011 8 0 0 0 2.55E+07 1.21E+07 - - - 2.257 0.9804 230117_WJC_METTL3_WT_vs_EV_F05.15588.15588.2 2.05 14-Oct R.IAVPVLVR[166.11].D sp|P52952|NKX25_HUMAN 1 875.5832 2.11 39648 15588 2 875.585741 438.7989 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 9.75 3233.6 - 223657 - - - 2.9101 - 1.444 0.032 - 375.1 1 2 0 0.0025 8 0 0 0 2.56E+07 1.21E+07 - - - 0.3847 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.15593.15593.2 0.00691 14-Jun K.FVADGIFK[136.11].A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 903.4946 1.74 39651 15593 2 903.49628 452.7546 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3234.2 - 2.25E+07 - - - 1.9104 - 1.367 0.371 - 99.4 1 2 0 0.0017 8 0 0 0 2.59E+09 1.49E+09 - - - 2.7235 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.15597.15597.2 0.0434 14-Jul R.FVDGLTFK.V "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 925.4909 0.92 39655 15597 2 925.491422 463.7527 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.84 3234.4 - 442153 - - - 0.5435 - 1.3 0.288 - 127.8 1 2 0 0.0005 8 0 0 0 1.32E+07 1.43E+07 - - - 1.9593 0.986 230117_WJC_METTL3_WT_vs_EV_F05.15602.15602.2 1.17 16-Jul R.FLPSPVVIK[136.11].K "sp|Q13618|CUL3_HUMAN,tr|H7C399|H7C399_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 3 1006.6307 0.62 39658 15602 2 1006.633008 504.3226 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 8.75 3235 - 1.39E+06 - - - 2.3385 - 1.149 0.13 - 130.5 1 2 0 0.0024 9 0 0 0 4.76E+07 7.70E+07 - - - 0.4023 0.9702 230117_WJC_METTL3_WT_vs_EV_F05.15605.15605.2 4.2 16-Jul R.FLPSPVVIK.K "sp|Q13618|CUL3_HUMAN,tr|H7C399|H7C399_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 3 998.6165 0.62 39661 15605 2 998.61875 500.3155 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 8.75 3235.2 - 397620 - - - 2.2992 - 1.258 0.024 - 133.5 1 2 0 0.0023 9 0 0 0 4.76E+07 7.69E+07 - - - -0.1184 0.9962 230117_WJC_METTL3_WT_vs_EV_F05.15606.15606.2 0.0354 16-Aug R.LWGEPVNLR.E "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 1082.5873 0.98 39662 15606 2 1082.590005 542.3009 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 6 3235.3 - 327738 - - - 2.518 - 1.563 0.153 - 203.8 1 2 0 0.0027 9 0 0 0 9.78E+06 9.99E+06 - - - 1.4623 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.15609.15609.2 0.12 18-Jun R.LIYTAGGYFR.Q sp|Q14145|KEAP1_HUMAN 1 1159.6026 2.26 39663 15609 2 1159.604654 580.8086 Kelch-like ECH-associated protein 1 OS=Homo sapiens OX=9606 GN=KEAP1 PE=1 SV=2 8.59 3235.7 - 502925 - - - 1.7756 - 1.305 0.311 - 98.4 1 2 0 0.0021 10 0 0 0 7.17E+06 3.18E+06 - - - 2.0805 0.9486 230117_WJC_METTL3_WT_vs_EV_F05.15610.15610.2 0.00974 18-Sep R.PADVIFATVR.E sp|P33993|MCM7_HUMAN 1 1087.6026 3.67 39664 15610 2 1087.60429 544.8086 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 6.27 3235.9 - 628826 - - - 1.5585 - 2.011 0.249 - 253.7 1 1 0 0.0017 10 0 0 0 8.41E+06 2.29E+06 - - - 2.8297 0.9928 230117_WJC_METTL3_WT_vs_EV_F05.15611.15611.2 1.49 14-Jul K.NLYIISVK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 956.5786 1.32 39665 15611 2 956.58091 479.2966 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3235.9 - 1.56E+06 - - - 2.396 - 1.387 0.118 - 148.1 1 2 0 0.0023 8 0 0 0 3.45E+09 2.62E+09 - - - 0.8985 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.15612.15612.2 0.0899 12-Aug R.ITILLPK.R "sp|Q9BT43|RPC7L_HUMAN,tr|A6NGX6|A6NGX6_HUMAN,tr|A0A0D9SG24|A0A0D9SG24_HUMAN" 3 796.5422 1.75 39666 15612 2 796.542999 399.2784 DNA-directed RNA polymerase III subunit RPC7-like OS=Homo sapiens OX=9606 GN=POLR3GL PE=1 SV=1 8.75 3236 - 1.17E+06 - - - 0.9704 - 1.726 0.242 - 156.1 1 2 0 0.0008 7 0 0 0 1.66E+07 9.50E+06 - - - 2.5576 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15617.15617.2 0.002 14-Aug K.VFNLGVYR.R "sp|O60825|F262_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN" 2 966.5287 0.56 39669 15617 2 966.530505 484.2716 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 8.72 3236.6 - 1.34E+06 - - - 1.8665 - 1.722 0.322 - 229.3 1 2 0 0.0018 8 0 0 0 2.67E+07 4.78E+07 - - - 3.0579 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.15618.15618.2 0.0633 14-Aug K.NLYIISVK.G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 948.5644 1.32 39670 15618 2 948.565971 475.2895 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3236.7 - 1.67E+06 - - - 1.6372 - 1.451 0.238 - 224.1 1 2 0 0.0016 8 0 0 0 3.45E+09 2.62E+09 - - - 1.9211 0.997 230117_WJC_METTL3_WT_vs_EV_F05.15620.15620.2 0.181 18-Jun R.IVLVDDSIVR[166.11].G sp|Q06203|PUR1_HUMAN 1 1137.6633 1.86 39672 15620 2 1137.663539 569.8389 Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1 4.21 3236.9 - 392116 - - - 0.2154 - 1.537 0.186 - 73 1 2 0 0.0002 10 0 0 0 4.09E+07 2.19E+07 - - - 1.6145 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.15624.15624.2 0.178 18-Sep R.IVLVDDSIVR.G sp|Q06203|PUR1_HUMAN 1 1127.655 1.87 39674 15624 2 1127.656506 564.8348 Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1 4.21 3237.5 - 440138 - - - 1.3142 - 1.724 0.235 - 234.5 1 2 0 0.0015 10 0 0 0 4.11E+07 2.19E+07 - - - 2.2965 1 230117_WJC_METTL3_WT_vs_EV_F05.15625.15625.2 0.000129 20-Oct R.LFSGDVVLTAR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1186.6585 0.99 39675 15625 2 1186.659934 594.3365 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3237.6 - 531211 - - - 1.1722 - 2.032 0.504 - 280 1 2 0 0.0014 11 0 0 0 2.16E+08 2.18E+08 - - - 4.6812 0.999 230117_WJC_METTL3_WT_vs_EV_F05.15627.15627.2 0.00167 14-Jun R.LFC[160.03]VGFTK.K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 970.4946 0.84 39677 15627 2 970.494854 486.2546 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.22 3237.8 - 546471 - - - 0.237 - 1.421 0.342 - 86.7 1 2 0 0.0002 8 0 0 0 3.46E+08 4.13E+08 - - - 2.6266 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.15628.15628.2 0.00015 20-Nov R.LFSGDVVLTAR.D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1176.6503 0.99 39678 15628 2 1176.652613 589.3324 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3238 - 368254 - - - 1.9887 - 2.207 0.452 - 386.8 1 2 0 0.0023 11 0 0 0 2.16E+08 2.18E+08 - - - 4.5203 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.15633.15633.2 0.013 14-Jul R.LLPSLIGR[166.11].H "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 4 877.5625 0.76 39681 15633 2 877.563688 439.7885 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 9.75 3238.6 - 1.27E+06 - - - 1.4016 - 1.427 0.279 - 188.9 1 2 0 0.0012 8 0 0 0 6.51E+07 8.56E+07 - - - 2.1737 0.9964 230117_WJC_METTL3_WT_vs_EV_F05.15634.15634.2 0.114 12-Jun K.FVSELWK[136.11].D sp|P35579|MYH9_HUMAN 1 915.4946 0.63 39682 15634 2 915.493933 458.7546 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6 3238.7 - 4.17E+06 - - - -0.6783 - 1.322 0.268 - 89.9 1 2 0 -0.0006 7 0 0 0 9.41E+07 1.49E+08 - - - 1.9047 0.9784 230117_WJC_METTL3_WT_vs_EV_F05.15635.15635.2 0.119 16-Oct K.EALEAVLIK[136.11].G "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 992.5997 1.95 39683 15635 2 992.606771 497.3072 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 4.53 3238.8 - 469002 - - - 7.0754 - 1.672 0.283 - 231.8 1 2 0 0.007 9 0 0 0 2.18E+07 1.12E+07 - - - 2.6161 1 230117_WJC_METTL3_WT_vs_EV_F05.15636.15636.2 2.96E-06 26-Nov K.VLEQLTGQTPVFSK[136.11].A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1553.8545 1.32 39684 15636 2 1553.854744 777.9345 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3238.9 - 249254 - - - 0.1834 - 2.282 0.55 - 377.5 1 2 0 0.0003 14 0 0 0 6.18E+06 4.69E+06 - - - 5.1736 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.15641.15641.2 0.000588 14-Sep R.LFC[160.03]VGFTK[136.11].K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 978.5088 0.84 39687 15641 2 978.510759 490.2617 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.22 3239.5 - 5.25E+06 - - - 1.9775 - 1.692 0.468 - 254.1 1 2 0 0.0019 8 0 0 0 3.45E+08 4.12E+08 - - - 4.0832 0.9956 230117_WJC_METTL3_WT_vs_EV_F05.15644.15644.2 0.392 14-Aug K.TAVLTLIR.E "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 8 885.5648 1.16 39690 15644 2 885.56821 443.7897 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 9.41 3239.8 - 1.96E+06 - - - 3.9037 - 1.514 0.242 - 294.4 1 2 0 0.0035 8 0 0 0 1.46E+08 1.26E+08 - - - 2.0782 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.15646.15646.2 0.186 14-Jul R.LLPSLIGR.H "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 4 867.5542 0.76 39692 15646 2 867.55505 434.7844 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 9.75 3240 - 1.50E+06 - - - 0.9936 - 1.411 0.295 - 178.9 1 2 0 0.0009 8 0 0 0 6.50E+07 8.56E+07 - - - 2.258 1 230117_WJC_METTL3_WT_vs_EV_F05.15647.15647.2 2.74E-05 26-Nov K.VLEQLTGQTPVFSK.A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1545.8403 1.32 39693 15647 2 1545.84211 773.9274 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3240.2 - 366592 - - - 1.1974 - 2.429 0.569 - 244.4 1 2 0 0.0019 14 0 0 0 6.18E+06 4.69E+06 - - - 5.4701 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15648.15648.2 0.00539 22-Sep R.VLVTGATGLLGR[166.11].A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1165.7058 1.42 39694 15648 2 1165.706194 583.8602 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3240.3 - 325868 - - - 0.314 - 1.625 0.417 - 223.7 1 2 0 0.0004 12 0 0 0 2.61E+07 1.84E+07 - - - 3.3983 0.996 230117_WJC_METTL3_WT_vs_EV_F05.15658.15658.2 0.183 12-Jun K.VLFTC[160.03]FK[136.11].R "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 921.4874 1.99 39700 15658 2 921.489089 461.751 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 8.19 3241.5 - 1.10E+06 - - - 1.8752 - 1.075 0.26 - 89.6 1 2 0 0.0017 7 0 0 0 2.06E+07 1.04E+07 - - - 1.19 0.9969 230117_WJC_METTL3_WT_vs_EV_F05.15659.15659.2 0.137 14-Aug R.TVETLLLR.F "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 6 943.5702 0.49 39701 15659 2 943.572259 472.7924 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 5.66 3241.6 - 1.66E+06 - - - 2.1482 - 1.293 0.225 - 185.1 1 2 0 0.002 8 0 0 0 8.73E+07 1.78E+08 - - - 1.4772 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.15660.15660.2 0.238 16-Jul K.LIPPQDILR[166.11].D sp|Q96A65|EXOC4_HUMAN 1 1073.6472 1.6 39702 15660 2 1073.647487 537.8309 Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1 5.84 3241.8 - 260984 - - - 0.2207 - 1.223 0.261 - 105.3 1 2 0 0.0002 9 0 0 0 1.53E+07 9.58E+06 - - - 1.5511 0.994 230117_WJC_METTL3_WT_vs_EV_F05.15667.15667.2 0.0774 16-Jul R.FFMGNQVLK[136.11].V sp|P13010|XRCC5_HUMAN 1 1090.5725 0.84 39707 15667 2 1090.575155 546.2935 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3242.6 - 249924 - - - 2.4464 - 1.205 0.201 - 93.2 1 2 0 0.0027 9 0 0 0 6.12E+07 7.32E+07 - - - 1.0642 1 230117_WJC_METTL3_WT_vs_EV_F05.15671.15671.2 0.000143 22-Dec R.VLVTGATGLLGR.A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1155.6976 1.42 39709 15671 2 1155.699904 578.8561 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3243.1 - 856859 - - - 2.0299 - 2.218 0.517 - 417.6 1 2 0 0.0023 12 0 0 0 2.61E+07 1.84E+07 - - - 4.9548 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15673.15673.2 0.00613 16-Sep K.EALEAVLIK.G "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 984.5855 1.95 39711 15673 2 984.586526 493.3001 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 4.53 3243.3 - 965210 - - - 0.9933 - 1.842 0.308 - 183.8 1 2 0 0.001 9 0 0 0 2.18E+07 1.12E+07 - - - 3.0828 0.996 230117_WJC_METTL3_WT_vs_EV_F05.15675.15675.2 0.0431 16-Aug R.FFMGNQVLK.V sp|P13010|XRCC5_HUMAN 1 1082.5583 0.84 39713 15675 2 1082.556423 542.2864 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3243.5 - 475482 - - - -1.7218 - 1.4 0.33 - 133.9 1 2 0 -0.0019 9 0 0 0 6.12E+07 7.32E+07 - - - 2.4512 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.15680.15680.2 0.0176 14-Jun R.ELYPVEFR.N "sp|Q5BJF2|SGMR2_HUMAN,tr|J3KT68|J3KT68_HUMAN" 2 1051.5338 1.13 39715 15680 2 1051.533134 526.7742 Sigma intracellular receptor 2 OS=Homo sapiens OX=9606 GN=TMEM97 PE=1 SV=1 4.53 3244.2 - 348168 - - - -0.6771 - 1.355 0.396 - 147.3 1 2 0 -0.0007 8 0 0 0 2.04E+07 1.81E+07 - - - 2.8819 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15688.15688.2 0.00755 18-Sep R.LVPLQEEIYR.K "sp|Q2NKX8|ERC6L_HUMAN,tr|B5MDQ0|B5MDQ0_HUMAN" 2 1258.6921 4.07 39721 15688 2 1258.69363 630.3533 DNA excision repair protein ERCC-6-like OS=Homo sapiens OX=9606 GN=ERCC6L PE=1 SV=1 4.53 3245.2 - 218152 - - - 1.1854 - 1.732 0.328 - 357.5 1 2 0 0.0015 10 0 0 0 8.33E+06 2.05E+06 - - - 2.9963 0.9947 230117_WJC_METTL3_WT_vs_EV_F05.15699.15699.2 0.384 18-Jul R.GLIENPALLR[166.11].W sp|O95168|NDUB4_HUMAN 1 1104.6531 1.22 39726 15699 2 1104.655929 553.3338 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3 6 3246.7 - 291946 - - - 2.5936 - 1.468 0.168 - 101.7 2 2 0 0.0029 10 0 0 0 2.98E+07 2.43E+07 - - - 1.2181 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.15709.15709.2 0.139 14-Jun K.EMVELPLR[166.11].H "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN" 10 995.5349 0.69 39731 15709 2 995.537073 498.7747 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.53 3248.1 - 423503 - - - 2.1596 - 1.454 0.249 - 118.9 1 2 0 0.0022 8 0 0 0 1.42E+07 2.06E+07 - - - 2.0084 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.15711.15711.2 0.182 14-Jun K.EMVELPLR.H "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN" 10 985.5267 0.69 39732 15711 2 985.529324 493.7706 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.53 3248.3 - 418348 - - - 2.7102 - 1.335 0.254 - 88.6 1 2 0 0.0027 8 0 0 0 1.42E+07 2.05E+07 - - - 1.7876 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.15716.15716.2 0.711 14-Sep K.TAVLTLIR[166.11].E "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 8 895.573 1.16 39734 15716 2 895.573835 448.7938 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 9.41 3249 - 3.27E+06 - - - 0.9067 - 1.506 0.187 - 304.2 1 2 0 0.0008 8 0 0 0 1.46E+08 1.26E+08 - - - 1.6568 0.9943 230117_WJC_METTL3_WT_vs_EV_F05.15717.15717.2 1.02 16-Jul R.ILPQDVILK[136.11].F "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1045.6627 1.16 39735 15717 2 1045.663537 523.8386 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.84 3249.1 - 594757 - - - 0.8177 - 1.298 0.152 - 102.3 1 2 0 0.0009 9 0 0 0 2.54E+07 2.20E+07 - - - 0.918 1 230117_WJC_METTL3_WT_vs_EV_F05.15720.15720.3 1.83E-11 19/64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 25.43 39736 15720 3 1786.984407 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3249.5 - 564199 - - - 0.8433 - 3.632 0.503 - 343.4 1 2 0 0.0015 17 0 0 0 3.66E+07 1.44E+06 - - - 7.4059 0.9677 230117_WJC_METTL3_WT_vs_EV_F05.15726.15726.2 4.29 12-Jun R.VGDQILR[166.11].V sp|Q9P202|WHRN_HUMAN 1 809.4635 1.25 39741 15726 2 809.465462 405.739 Whirlin OS=Homo sapiens OX=9606 GN=WHRN PE=1 SV=4 5.81 3250.2 - 273029 - - - 2.4584 - 1.076 0.082 - 94.5 1 2 0 0.002 7 0 0 0 1.40E+07 1.12E+07 - - - -0.1219 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.15728.15728.2 0.28 12-Jul K.SIELFYK[136.11].F sp|P78527|PRKDC_HUMAN 1 906.4942 0.87 39742 15728 2 906.495445 454.2544 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.72 3250.6 - 1.21E+06 - - - 1.3514 - 1.074 0.242 - 170.5 1 2 0 0.0012 7 0 0 0 2.61E+07 2.98E+07 - - - 1.0542 0.9948 230117_WJC_METTL3_WT_vs_EV_F05.15730.15730.2 0.826 12-Jul R.VLAAFLR.R "sp|Q9HB09|B2L12_HUMAN,sp|Q99607|ELF4_HUMAN,tr|M0R1Z8|M0R1Z8_HUMAN,tr|A0A087WU18|A0A087WU18_HUMAN,tr|I6LJZ9|I6LJZ9_HUMAN,tr|A0A087WSV0|A0A087WSV0_HUMAN,tr|I6LK00|I6LK00_HUMAN,tr|I6LJZ7|I6LJZ7_HUMAN,tr|M0R1K0|M0R1K0_HUMAN,tr|M0QZM6|M0QZM6_HUMAN" 10 788.4909 2.91 39744 15730 2 788.492573 395.2527 Bcl-2-like protein 12 OS=Homo sapiens OX=9606 GN=BCL2L12 PE=1 SV=1 9.72 3250.8 - 944526 - - - 2.1738 - 1.464 0.111 - 156.3 1 2 0 0.0017 7 0 0 0 2.67E+07 9.15E+06 - - - 1.0681 0.9602 230117_WJC_METTL3_WT_vs_EV_F05.15733.15733.2 2.16 22-Jun K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.19 39747 15733 2 1277.751269 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3251.2 - 324299 - - - 1.3117 - 1.123 0.07 - 54.1 5 2 0 0.0017 12 0 0 0 2.28E+07 1.91E+07 - - - -0.4495 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.15736.15736.2 0.215 12-Jun K.AFLFVNK.G sp|Q8N0X7|SPART_HUMAN 1 837.4749 1.41 39748 15736 2 837.476823 419.7447 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3251.6 - 6.37E+06 - - - 2.326 - 1.256 0.269 - 165.9 1 2 0 0.0019 7 0 0 0 1.71E+08 1.21E+08 - - - 1.7494 0.9943 230117_WJC_METTL3_WT_vs_EV_F05.15738.15738.2 0.0504 12-Jun K.AFLFVNK[136.11].G sp|Q8N0X7|SPART_HUMAN 1 845.4891 1.41 39750 15738 2 845.491563 423.7518 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3251.8 - 3.72E+06 - - - 2.9427 - 1.195 0.232 - 162.2 1 2 0 0.0025 7 0 0 0 1.73E+08 1.22E+08 - - - 1.3182 0.994 230117_WJC_METTL3_WT_vs_EV_F05.15739.15739.2 0.443 14-Jun K.FVIPLHSA.- sp|Q96F86|EDC3_HUMAN 1 882.4963 - 39751 15739 2 882.498746 442.2554 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 6.74 3251.9 - 948165 - - - 2.7275 - 1.194 0.216 - 119.3 1 2 0 0.0024 8 0 0 0 - - - - - 1.1704 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.15742.15742.2 0.187 20-Sep K.ALILVGGYGTR.L "sp|Q9Y5P6|GMPPB_HUMAN,tr|A0A7I2V691|A0A7I2V691_HUMAN,tr|A0A7I2V2Y5|A0A7I2V2Y5_HUMAN,tr|A0A7I2YQI5|A0A7I2YQI5_HUMAN,tr|A0A7I2V4B5|A0A7I2V4B5_HUMAN" 5 1118.6448 0.6 39754 15742 2 1118.647743 560.3297 Mannose-1-phosphate guanyltransferase beta OS=Homo sapiens OX=9606 GN=GMPPB PE=1 SV=2 8.79 3252.2 - 266894 - - - 2.6362 - 2.006 0.216 - 221.3 1 2 0 0.0029 11 0 0 0 8.40E+06 1.40E+07 - - - 2.5187 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.15750.15750.2 0.0292 18-Oct R.GLIENPALLR.W sp|O95168|NDUB4_HUMAN 1 1094.6448 1.22 39760 15750 2 1094.64821 548.3297 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3 6 3253.2 - 1.85E+06 - - - 3.1206 - 1.793 0.185 - 231.1 1 2 0 0.0034 10 0 0 0 2.98E+07 2.43E+07 - - - 2.0362 0.9915 230117_WJC_METTL3_WT_vs_EV_F05.15752.15752.2 1.72 12-Jul R.SVINLLR.N "sp|Q96AT9|RPE_HUMAN,sp|Q2QD12|RPEL1_HUMAN,tr|C9J6A7|C9J6A7_HUMAN" 3 813.5072 1.55 39762 15752 2 813.510539 407.7609 Ribulose-phosphate 3-epimerase OS=Homo sapiens OX=9606 GN=RPE PE=1 SV=1 9.47 3253.5 - 270654 - - - 4.0577 - 1.294 0.234 - 135.8 1 2 0 0.0033 7 0 0 0 1.33E+07 8.55E+06 - - - 1.5849 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.15753.15753.3 1.35E-06 Dec-64 R.IINEPTAAAIAYGLDK[136.11]K[136.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1803.0113 24.93 39763 15753 3 1803.015193 602.011 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3253.6 - 260905 - - - 2.1592 - 2.616 0.502 - 132.1 1 2 0 0.0039 17 0 0 0 3.58E+07 1.44E+06 - - - 6.5651 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.15754.15754.2 0.0366 14-Jul K.VEILTALR[166.11].K "sp|Q8WZA0|LZIC_HUMAN,tr|K7ES95|K7ES95_HUMAN" 2 923.5679 2.34 39764 15754 2 923.570608 462.7912 Protein LZIC OS=Homo sapiens OX=9606 GN=LZIC PE=1 SV=1 5.97 3253.7 - 324331 - - - 2.892 - 1.372 0.306 - 117.8 1 2 0 0.0027 8 0 0 0 1.95E+07 8.35E+06 - - - 2.2541 0.9936 230117_WJC_METTL3_WT_vs_EV_F05.15767.15767.2 0.0552 16-Jun R.YMVALQIAR[166.11].E sp|Q7KZ85|SPT6H_HUMAN 1 1073.5931 1.31 39775 15767 2 1073.593806 537.8038 Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2 8.75 3255.2 - 308854 - - - 0.652 - 1.131 0.2 - 76.4 1 2 0 0.0007 9 0 0 0 4.02E+06 3.08E+06 - - - 0.8741 0.9819 230117_WJC_METTL3_WT_vs_EV_F05.15768.15768.2 0.31 14-Jul R.LFC[160.03]VGFTK[136.11].K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 978.5088 0.84 39776 15768 2 978.512796 490.2617 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.22 3255.4 - 602684 - - - 4.0592 - 1.219 0.181 - 96.8 1 2 0 0.004 8 0 0 0 3.45E+08 4.12E+08 - - - 0.9739 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.15773.15773.2 0.114 16-Oct R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 0.75 39779 15773 2 960.612369 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3256 - 4.42E+06 - - - 2.5515 - 1.748 0.236 - 298.8 1 2 0 0.0025 9 0 0 0 1.18E+10 1.58E+10 - - - 2.399 0.9954 230117_WJC_METTL3_WT_vs_EV_F05.15774.15774.2 0.109 16-Aug R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 0.75 39780 15774 2 952.597531 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3256.1 - 2.71E+06 - - - 1.9032 - 1.434 0.137 - 198.5 1 2 0 0.0018 9 0 0 0 1.18E+10 1.58E+10 - - - 1.0952 0.9607 230117_WJC_METTL3_WT_vs_EV_F05.15775.15775.2 0.0343 18-Nov H.ILSPWGAEVK[136.11].A "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1106.6215 0.67 39781 15775 2 1106.622831 554.318 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3256.1 - 1.08E+06 - - - 1.1612 - 2.086 0.284 - 293.1 1 1 0 0.0013 10 0 0 0 5.70E+07 8.50E+07 - - - 3.1905 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15777.15777.2 2.38E-05 14-Aug K.YFEYIMAK[136.11].E sp|P13674|P4HA1_HUMAN 1 1071.5191 2.57 39783 15777 2 1071.521321 536.7668 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3256.4 - 400169 - - - 2.1157 - 1.408 0.417 - 181.2 1 2 0 0.0023 8 0 0 0 4.24E+07 1.65E+07 - - - 3.1522 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.15779.15779.2 0.1 16-Aug R.ILPQDVILK.F "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1037.6485 1.11 39785 15779 2 1037.650281 519.8315 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.84 3256.6 - 580807 - - - 1.7337 - 1.332 0.217 - 141.8 1 2 0 0.0018 9 0 0 0 3.64E+07 3.28E+07 - - - 1.4726 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.15786.15786.2 0.154 14-Aug K.YFEYIMAK.E sp|P13674|P4HA1_HUMAN 1 1063.5049 2.59 39790 15786 2 1063.505194 532.7597 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3257.5 - 1.33E+06 - - - 0.3197 - 1.549 0.291 - 172.5 1 2 0 0.0003 8 0 0 0 4.24E+07 1.64E+07 - - - 2.51 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.15788.15788.2 0.000119 18-Oct K.AFADSSYLLR[166.11].H "sp|Q9H5H4|ZN768_HUMAN,tr|H3BS42|H3BS42_HUMAN" 2 1151.585 0.82 39792 15788 2 1151.589024 576.7998 Zinc finger protein 768 OS=Homo sapiens OX=9606 GN=ZNF768 PE=1 SV=2 5.88 3257.8 - 351395 - - - 3.4561 - 1.458 0.439 - 281.6 1 2 0 0.004 10 0 0 0 1.12E+07 1.37E+07 - - - 3.3347 0.9502 230117_WJC_METTL3_WT_vs_EV_F05.15789.15789.2 4.69 14-Jun K.GFEYILAK.L "sp|Q9Y255|PRLD1_HUMAN,tr|H0YA79|H0YA79_HUMAN" 2 939.5066 0.83 39793 15789 2 939.50807 470.7606 "PRELI domain-containing protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=PRELID1 PE=1 SV=1" 6 3257.9 - 183787 - - - 1.5976 - 1.029 0.068 - 68.5 3 2 0 0.0015 8 0 0 0 6.24E+08 7.49E+08 - - - -0.5841 0.9962 230117_WJC_METTL3_WT_vs_EV_F05.15790.15790.2 0.072 16-Jul R.VFNPYTEFK.E sp|Q96C19|EFHD2_HUMAN 1 1143.5601 1.49 39794 15790 2 1143.561207 572.7873 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 5.97 3258 - 326551 - - - 1.0021 - 1.119 0.25 - 116.1 1 2 0 0.0011 9 0 0 0 1.84E+07 1.23E+07 - - - 1.2124 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.15793.15793.2 0.000911 18-Sep K.IGDLGLATLK.R "sp|Q9H4A3|WNK1_HUMAN,sp|Q96J92|WNK4_HUMAN,sp|Q9Y3S1|WNK2_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A6PVV2|A6PVV2_HUMAN,tr|K7ENT7|K7ENT7_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 9 999.5964 2.04 39795 15793 2 999.60017 500.8055 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 5.84 3258.4 - 1.48E+06 - - - 3.7245 - 1.766 0.366 - 150.3 1 2 0 0.0037 10 0 0 0 1.14E+08 5.58E+07 - - - 3.3306 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.15796.15796.2 0.000207 16-Sep R.VFNPYTEFK.E sp|Q96C19|EFHD2_HUMAN 1 1143.5601 1.49 39798 15796 2 1143.562986 572.7873 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 5.97 3258.8 - 399618 - - - 2.5578 - 1.616 0.448 - 235.2 1 2 0 0.0029 9 0 0 0 1.84E+07 1.23E+07 - - - 3.7375 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.15804.15804.2 0.00324 12-Jul K.QC[160.03]FLVLR.Q "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|H7C278|H7C278_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 5 934.5059 0.63 39804 15804 2 934.507185 468.2602 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 8.25 3259.6 - 2.16E+06 - - - 1.42 - 1.533 0.399 - 282.5 1 2 0 0.0013 7 0 0 0 2.28E+07 3.62E+07 - - - 3.3413 0.9665 230117_WJC_METTL3_WT_vs_EV_F05.15810.15810.2 0.0223 14-Jun K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 2.4 39809 15810 2 895.485742 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3260.4 - 382447 - - - 6.0169 - 1.253 0.246 - 88.2 1 2 0 0.0054 8 0 0 0 1.27E+07 5.30E+06 - - - 1.5365 0.9939 230117_WJC_METTL3_WT_vs_EV_F05.15811.15811.2 0.666 12-Jul R.VLQLFTR[166.11].L "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 885.5312 1.29 39810 15811 2 885.530533 443.7729 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 9.72 3260.5 - 1.72E+06 - - - -0.7058 - 1.43 0.173 - 151.1 1 2 0 -0.0006 7 0 0 0 3.94E+07 3.05E+07 - - - 1.4519 0.9939 230117_WJC_METTL3_WT_vs_EV_F05.15814.15814.2 0.17 16-Aug K.IYPVGYFTK.E "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 1086.575 0.13 39811 15814 2 1086.576197 544.2948 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.5 3260.9 - 276564 - - - 1.1173 - 1.266 0.15 - 146.4 1 2 0 0.0012 9 0 0 0 5.47E+06 4.38E+07 - - - 0.8309 0.9819 230117_WJC_METTL3_WT_vs_EV_F05.15822.15822.2 3.77 12-May K.ILIWSGR.F "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 843.4967 1.57 39817 15822 2 843.496464 422.7556 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 9.75 3261.8 - 2.17E+06 - - - -0.2478 - 1.23 0.098 - 92.5 1 2 0 -0.0002 7 0 0 0 8.95E+07 5.72E+07 - - - 0.4207 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.15823.15823.2 0.00716 20-Oct R.ILMVGLDAAGK.T "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|F5H1V1|F5H1V1_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|F5H6T5|F5H6T5_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|F8WDB3|F8WDB3_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 11 1086.6107 1.74 39818 15823 2 1086.612373 544.3126 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3261.9 - 402292 - - - 1.524 - 1.877 0.351 - 238.3 1 2 0 0.0017 11 0 0 0 2.70E+08 1.55E+08 - - - 3.3364 0.9869 230117_WJC_METTL3_WT_vs_EV_F05.15824.15824.2 0.585 12-Jun R.LYDGLFK.V "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 10 854.4538 1.49 39819 15824 2 854.454454 428.2342 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.83 3261.9 - 1.56E+06 - - - 0.7595 - 1.054 0.153 - 78.6 1 2 0 0.0006 7 0 0 0 1.99E+08 1.34E+08 - - - 0.3375 0.9328 230117_WJC_METTL3_WT_vs_EV_F05.15825.15825.2 1.45 12-May R.VLQLFTR.L "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 875.5229 1.3 39820 15825 2 875.521289 438.7687 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 9.72 3262 - 934994 - - - -1.8263 - 1.147 0.095 - 62.8 1 2 0 -0.0016 7 0 0 0 3.94E+07 3.02E+07 - - - 0.1767 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.15828.15828.2 0.0223 14-Aug K.GIAYIEFK[136.11].T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 947.5208 0.83 39822 15828 2 947.521662 474.7677 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3262.3 - 1.08E+07 - - - 0.9425 - 1.497 0.265 - 204 1 2 0 0.0009 8 0 0 0 6.23E+08 7.49E+08 - - - 2.2148 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.15836.15836.2 8.04E-05 16-Jun K.VLPVGVLYK.V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 986.6165 0.56 39826 15836 2 986.616476 494.3155 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3263.2 - 377593 - - - 0.0223 - 1.666 0.378 - 77 1 2 0 0 9 0 0 0 1.19E+08 2.14E+08 - - - 3.3096 0.999 230117_WJC_METTL3_WT_vs_EV_F05.15837.15837.2 0.0795 18-Oct R.LGFVAGVINR[166.11].E "sp|Q93050|VPP1_HUMAN,tr|K7EN36|K7EN36_HUMAN,tr|K7EPG4|K7EPG4_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 5 1054.6163 1.77 39827 15837 2 1054.617086 528.3154 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 9.75 3263.3 - 482697 - - - 0.7605 - 1.866 0.226 - 273.2 1 2 0 0.0008 10 0 0 0 2.36E+07 1.33E+07 - - - 2.4512 0.9885 230117_WJC_METTL3_WT_vs_EV_F05.15857.15857.2 0.418 14-Jun R.VLSPLIIK.S sp|Q8NCN4|RN169_HUMAN 1 881.595 2.2 39840 15857 2 881.595298 441.8048 E3 ubiquitin-protein ligase RNF169 OS=Homo sapiens OX=9606 GN=RNF169 PE=1 SV=2 8.72 3265.6 - 617188 - - - 0.3494 - 1.233 0.134 - 69.9 2 2 0 0.0003 8 0 0 0 1.52E+07 6.90E+06 - - - 0.5278 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.15858.15858.2 0.0181 16-Oct R.LLLQLEATK.N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1027.6277 8.26 39841 15858 2 1027.62594 514.8211 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3265.7 - 1.64E+06 - - - -1.7584 - 2.041 0.322 - 271.3 1 2 0 -0.0018 9 0 0 0 6.85E+08 8.29E+07 - - - 3.4827 0.9884 230117_WJC_METTL3_WT_vs_EV_F05.15860.15860.2 1.31 12-Jun K.ILIEDWK[136.11].K "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A7I2V2T6|A0A7I2V2T6_HUMAN,tr|K7EPW7|K7EPW7_HUMAN" 4 923.5208 1.34 39843 15860 2 923.52128 462.7677 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 4.37 3266 - 1.08E+06 - - - 0.5533 - 1.297 0.081 - 93.4 1 2 0 0.0005 7 0 0 0 3.57E+07 2.66E+07 - - - 0.4631 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.15866.15866.3 0.000378 Nov-36 R.ILIAKPIMFR.G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1200.7417 1.62 39847 15866 3 1200.741471 401.2545 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3266.7 - 1.01E+06 - - - -0.1666 - 1.989 0.383 - 119.1 1 2 0 -0.0002 10 0 0 0 2.51E+08 1.55E+08 - - - 4.8182 0.9714 230117_WJC_METTL3_WT_vs_EV_F05.15867.15867.2 4.61 12-May R.LFFVGSR[166.11].E "sp|Q9UM01|YLAT1_HUMAN,sp|Q92536|YLAT2_HUMAN,sp|Q01650|LAT1_HUMAN,tr|H0YJ95|H0YJ95_HUMAN,tr|A0A0C4DGL4|A0A0C4DGL4_HUMAN,tr|G3V4Z6|G3V4Z6_HUMAN" 6 834.4627 0.97 39848 15867 2 834.46276 418.2386 Y+L amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A7 PE=1 SV=2 9.75 3266.8 - 1.40E+06 - - - 0.0192 - 1.188 0.115 - 83.9 9 2 0 0 7 0 0 0 2.65E+07 2.73E+07 - - - 0.01 0.9487 230117_WJC_METTL3_WT_vs_EV_F05.15868.15868.2 0.5 14-Sep R.TAYLLYYR[166.11].R sp|Q14694|UBP10_HUMAN 1 1071.5629 0.99 39849 15868 2 1071.558843 536.7887 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.16 3267 - 814742 - - - -3.7413 - 1.247 0.209 - 258.5 1 2 0 -0.004 8 0 0 0 3.49E+07 3.53E+07 - - - 1.2492 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.15871.15871.2 0.000932 16-Aug K.VLPVGVLYK[136.11].V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 994.6307 0.56 39850 15871 2 994.631203 498.3226 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3267.4 - 1.94E+07 - - - 0.552 - 1.422 0.46 - 124.9 1 2 0 0.0005 9 0 0 0 1.19E+08 2.14E+08 - - - 3.4569 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15873.15873.2 0.00214 16-Sep R.MNVLADALK.S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 973.5267 1.34 39852 15873 2 973.526439 487.7706 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3267.5 - 2.72E+06 - - - -0.2198 - 1.979 0.382 - 222.6 1 2 0 -0.0002 9 0 0 0 5.75E+08 4.30E+08 - - - 3.8372 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.15874.15874.2 0.0677 18-Sep K.ILPEEITNLR.N sp|Q9H9A6|LRC40_HUMAN 1 1196.6765 0.94 39853 15874 2 1196.678795 599.3455 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3267.6 - 1.18E+06 - - - 1.9278 - 1.624 0.294 - 312.9 1 2 0 0.0023 10 0 0 0 4.61E+07 4.89E+07 - - - 2.5652 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.15878.15878.2 1.45E-05 16-Oct R.MNVLADALK[136.11].S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 981.5409 1.34 39855 15878 2 981.539236 491.7777 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3268.2 - 3.17E+06 - - - -1.6474 - 2.127 0.44 - 421.1 1 2 0 -0.0016 9 0 0 0 5.75E+08 4.30E+08 - - - 4.4738 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.15879.15879.2 6.22E-05 18-Oct R.GYFEYIEENK.Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1290.5768 1.54 39856 15879 2 1290.579791 646.2957 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3268.3 - 416703 - - - 2.292 - 2.031 0.48 - 191.1 1 2 0 0.003 10 0 0 0 7.96E+06 5.16E+06 - - - 4.5631 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.15881.15881.2 0.333 16-Aug K.AGIPVYAWK[136.11].G sp|P23526|SAHH_HUMAN 1 1011.5633 82.52 39858 15881 2 1011.564773 506.7889 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 8.63 3268.5 - 1.63E+06 - - - 1.4542 - 1.421 0.234 - 108.5 1 2 0 0.0015 9 0 0 0 3.70E+09 4.48E+07 - - - 1.7854 0.9814 230117_WJC_METTL3_WT_vs_EV_F05.15888.15888.2 2.87 12-Jun K.ILIEDWK.K "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A7I2V2T6|A0A7I2V2T6_HUMAN,tr|K7EPW7|K7EPW7_HUMAN" 4 915.5066 1.34 39864 15888 2 915.507332 458.7606 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 4.37 3269.4 - 1.49E+06 - - - 0.8334 - 1.303 0.028 - 94.4 1 2 0 0.0008 7 0 0 0 3.58E+07 2.67E+07 - - - 0.0862 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15890.15890.2 0.203 16-Sep R.LLLQLEATK[136.11].N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1035.6419 7.72 39865 15890 2 1035.64149 518.8282 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3269.6 - 1.57E+06 - - - -0.4413 - 1.884 0.415 - 217.9 1 2 0 -0.0005 9 0 0 0 6.84E+08 8.86E+07 - - - 3.9385 0.9713 230117_WJC_METTL3_WT_vs_EV_F05.15896.15896.2 0.49 12-Jun R.LYDGLFK[136.11].V "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 10 862.468 1.82 39870 15896 2 862.467559 432.2413 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.83 3270.1 - 2.81E+06 - - - -0.5171 - 1.251 0.081 - 83.9 2 2 0 -0.0004 7 0 0 0 1.95E+08 1.07E+08 - - - 0.2142 0.9941 230117_WJC_METTL3_WT_vs_EV_F05.15898.15898.2 0.895 14-Jul R.GLVGIEFK.E sp|P15924|DESP_HUMAN 1 861.496 10.11 39871 15898 2 861.496737 431.7553 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 3270.3 - 6.01E+06 - - - 0.8508 - 1.354 0.127 - 139.7 1 2 0 0.0007 8 0 0 0 2.24E+08 2.22E+07 - - - 0.8928 0.999 230117_WJC_METTL3_WT_vs_EV_F05.15900.15900.2 0.103 20-Aug K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.13 39873 15900 2 1235.762048 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3270.6 - 620104 - - - 1.5294 - 1.745 0.246 - 242.6 1 2 0 0.0019 11 0 0 0 4.03E+08 3.56E+08 - - - 2.3635 0.9963 230117_WJC_METTL3_WT_vs_EV_F05.15903.15903.2 0.481 16-Dec R.TEIIILATR[166.11].T "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 10 1038.6313 1.85 39874 15903 2 1038.627837 520.3229 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.66 3271 - 1.37E+06 - - - -3.3015 - 2.356 0.331 - 581.9 1 2 0 -0.0034 9 0 0 0 1.20E+09 6.52E+08 - - - 3.9639 0.9921 230117_WJC_METTL3_WT_vs_EV_F05.15908.15908.2 0.143 16-Jun K.VIIDTLITK[136.11].L sp|O15164|TIF1A_HUMAN 1 1022.6467 0.24 39879 15908 2 1022.648774 512.3306 Transcription intermediary factor 1-alpha OS=Homo sapiens OX=9606 GN=TRIM24 PE=1 SV=3 5.81 3271.5 - 265268 - - - 2.03 - 1.175 0.165 - 70.8 1 2 0 0.0021 9 0 0 0 1.50E+07 6.15E+07 - - - 0.7256 0.9969 230117_WJC_METTL3_WT_vs_EV_F05.15911.15911.2 0.604 20-Sep K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.13 39880 15911 2 1245.77061 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3271.9 - 1.01E+06 - - - 1.7515 - 1.401 0.194 - 101.6 1 2 0 0.0022 11 0 0 0 4.03E+08 3.56E+08 - - - 1.3854 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.15912.15912.2 0.000556 18-Sep K.ILPEEITNLR[166.11].N sp|Q9H9A6|LRC40_HUMAN 1 1206.6848 0.94 39881 15912 2 1206.686609 604.3497 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3272.1 - 261348 - - - 1.534 - 1.723 0.416 - 318.3 1 2 0 0.0019 10 0 0 0 4.61E+07 4.89E+07 - - - 3.6317 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.15913.15913.2 5.43E-05 16-Sep K.VIVPNMEFR.A sp|P55060|XPO2_HUMAN 1 1103.5798 1.34 39882 15913 2 1103.580683 552.7972 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.97 3272.2 - 336571 - - - 0.8445 - 1.782 0.455 - 234.4 1 2 0 0.0009 9 0 0 0 1.44E+08 1.08E+08 - - - 4.0728 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.15914.15914.2 8.44E-05 20-Oct R.LVDAVLGAEIR.N "sp|Q9UBN7|HDAC6_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8Y758|A0A2R8Y758_HUMAN,tr|A0A2R8Y559|A0A2R8Y559_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 5 1154.6659 0.88 39883 15914 2 1154.670265 578.3402 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.37 3272.3 - 135712 - - - 3.7604 - 2.143 0.435 - 293.7 1 2 0 0.0043 11 0 0 0 4.32E+07 4.92E+07 - - - 4.3145 1 230117_WJC_METTL3_WT_vs_EV_F05.15917.15917.2 7.92E-05 13/20 R.LVDAVLGAEIR[166.11].N "sp|Q9UBN7|HDAC6_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8Y758|A0A2R8Y758_HUMAN,tr|A0A2R8Y559|A0A2R8Y559_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 5 1164.6742 0.88 39884 15917 2 1164.677531 583.3444 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.37 3272.7 - 979647 - - - 2.866 - 2.593 0.464 - 373.2 1 2 0 0.0033 11 0 0 0 4.32E+07 4.92E+07 - - - 5.0446 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15919.15919.2 0.144 14-Sep R.TLINELVK[136.11].G "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 7 936.5735 19.84 39886 15919 2 936.575558 469.294 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.66 3272.9 - 7.23E+06 - - - 2.1621 - 1.515 0.387 - 217.5 1 2 0 0.002 8 0 0 0 1.68E+09 8.44E+07 - - - 3.1516 0.9736 230117_WJC_METTL3_WT_vs_EV_F05.15920.15920.2 2.1 14-Jul K.LIELLAGK.A sp|Q9NW08|RPC2_HUMAN 1 855.543 0.98 39887 15920 2 855.543244 428.7788 DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2 6 3273 - 1.21E+06 - - - 0.339 - 1.105 0.084 - 98.9 1 2 0 0.0003 8 0 0 0 1.42E+07 1.45E+07 - - - -0.0375 0.9892 230117_WJC_METTL3_WT_vs_EV_F05.15921.15921.2 3.69 14-Sep K.LIELLAGK[136.11].A sp|Q9NW08|RPC2_HUMAN 1 863.5572 0.98 39888 15921 2 863.556019 432.7859 DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2 6 3273.1 - 1.17E+06 - - - -1.3143 - 1.822 0.061 - 200.1 1 2 0 -0.0011 8 0 0 0 1.42E+07 1.45E+07 - - - 1.3006 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.15924.15924.2 0.0568 14-Jul K.LLFVPC[160.03]SR[166.11].V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 1000.5403 0.79 39889 15924 2 1000.540814 501.2774 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.25 3273.5 - 1.77E+06 - - - 0.4717 - 1.564 0.222 - 157.8 1 2 0 0.0005 8 0 0 0 3.51E+07 4.47E+07 - - - 2.0294 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.15926.15926.2 0.0278 14-Jul K.AVWLPAVK.A "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 882.5327 1.39 39891 15926 2 882.534641 442.2736 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.8 3273.6 - 1.35E+06 - - - 2.1722 - 1.304 0.283 - 190.9 1 2 0 0.0019 8 0 0 0 3.76E+07 2.71E+07 - - - 1.9312 0.9292 230117_WJC_METTL3_WT_vs_EV_F05.15929.15929.2 3.15 18-Apr R.ILIAK[136.11]PIMFR[166.11].G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1218.7641 0.78 39894 15929 2 1218.766741 610.3893 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3273.9 - 238339 - - - 2.1333 - 1.136 0.03 - 45.3 6 2 0 0.0026 10 0 0 0 4.65E+06 5.94E+06 - - - -0.7299 1 230117_WJC_METTL3_WT_vs_EV_F05.15934.15934.2 3.97E-06 18-Dec K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 8.59 39897 15934 2 1149.584711 575.7982 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3274.5 - 547271 - - - 2.4809 - 2.287 0.488 - 577.7 1 2 0 0.0029 10 0 0 0 1.04E+09 1.21E+08 - - - 4.9536 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.15935.15935.2 0.00247 18-Oct R.TVPLLLAESK[136.11].F sp|Q709C8|VP13C_HUMAN 1 1077.6525 0.9 39898 15935 2 1077.651701 539.8335 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 5.66 3274.7 - 372478 - - - -0.7516 - 1.711 0.418 - 298.8 1 2 0 -0.0008 10 0 0 0 7.79E+06 8.64E+06 - - - 3.6272 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.15940.15940.2 0.107 14-Jul K.AVWLPAVK[136.11].A "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 890.5469 1.46 39901 15940 2 890.547929 446.2807 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.8 3275.2 - 799294 - - - 1.1285 - 1.298 0.266 - 182.4 1 2 0 0.001 8 0 0 0 3.72E+07 2.55E+07 - - - 1.792 0.998 230117_WJC_METTL3_WT_vs_EV_F05.15941.15941.2 0.064 24-Sep K.LGPGAGAGFGVLR.R "sp|Q9BUL5|PHF23_HUMAN,tr|I3L1N0|I3L1N0_HUMAN,tr|I3L410|I3L410_HUMAN,tr|I3L4Q4|I3L4Q4_HUMAN" 4 1170.6509 4.58 39902 15941 2 1170.651795 586.3327 PHD finger protein 23 OS=Homo sapiens OX=9606 GN=PHF23 PE=1 SV=1 9.75 3275.4 - 318280 - - - 0.7287 - 1.618 0.204 - 173 1 2 0 0.0009 13 0 0 0 1.97E+07 4.30E+06 - - - 1.7825 1 230117_WJC_METTL3_WT_vs_EV_F05.15942.15942.2 0.0134 18-Oct K.FAEAFEAIPR[166.11].A sp|P50990|TCPQ_HUMAN 1 1159.5901 8.59 39903 15942 2 1159.590882 580.8023 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3275.5 - 0 - - - 0.6494 - 2.217 0.505 - 329.1 1 2 0 0.0008 10 0 0 0 1.04E+09 1.21E+08 - - - 4.993 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.15948.15948.2 2.12 18-Aug R.LPAAFAPLPR.V "sp|O14561|ACPM_HUMAN,tr|H3BNE8|H3BNE8_HUMAN,tr|H3BNK3|H3BNK3_HUMAN" 3 1051.6179 2.23 39907 15948 2 1051.619286 526.8162 "Acyl carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAB1 PE=1 SV=3" 9.75 3276.3 - 328885 - - - 1.3646 - 1.527 0.218 - 148.5 1 2 0 0.0014 10 0 0 0 8.31E+06 3.73E+06 - - - 1.8323 0.9755 230117_WJC_METTL3_WT_vs_EV_F05.15953.15953.2 4.62 12-Jun R.LILQIGR[166.11].G "sp|Q9NP73|ALG13_HUMAN,tr|A0A096LNJ4|A0A096LNJ4_HUMAN,tr|A0A087WX43|A0A087WX43_HUMAN,tr|A0A087WTT9|A0A087WTT9_HUMAN,tr|D6RE84|D6RE84_HUMAN,tr|A0A096LP10|A0A096LP10_HUMAN,tr|A0A096LNL2|A0A096LNL2_HUMAN,tr|A0A1B0GVW6|A0A1B0GVW6_HUMAN" 8 821.5362 1.14 39909 15953 2 821.537314 411.7754 Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 OS=Homo sapiens OX=9606 GN=ALG13 PE=1 SV=2 9.75 3277 - 665615 - - - 1.3037 - 1.448 0 - 118 6 2 0 0.0011 7 0 0 0 4.82E+08 4.24E+08 - - - -0.134 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.15964.15964.2 0.674 14-Jun K.LFIGNLPR[166.11].E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 938.5577 2.13 39917 15964 2 938.558137 470.2861 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3278.2 - 516246 - - - 0.4581 - 1.328 0.203 - 113.5 1 2 0 0.0004 8 0 0 0 2.57E+09 1.21E+09 - - - 1.3958 0.9282 230117_WJC_METTL3_WT_vs_EV_F05.15965.15965.2 0.158 12-Aug R.QLSVLFR.K sp|Q96HR3|MED30_HUMAN 1 861.5072 2.62 39918 15965 2 861.514328 431.7609 Mediator of RNA polymerase II transcription subunit 30 OS=Homo sapiens OX=9606 GN=MED30 PE=1 SV=1 9.75 3278.3 - 409023 - - - 8.2298 - 1.617 0.179 - 276.8 1 2 0 0.0071 7 0 0 0 2.25E+07 8.58E+06 - - - 1.8836 0.9363 230117_WJC_METTL3_WT_vs_EV_F05.15971.15971.2 0.857 18-Jun R.VPFLVAETPR[166.11].A sp|Q13131|AAPK1_HUMAN 1 1137.6422 8.81 39921 15971 2 1137.646405 569.8284 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4 5.97 3279.1 - 154850 - - - 3.727 - 1.396 0.058 - 75.7 12 2 0 0.0042 10 0 0 0 1.34E+07 1.52E+06 - - - -0.0828 0.873 230117_WJC_METTL3_WT_vs_EV_F05.15972.15972.2 3.92 12-Aug S.LIQLLGR.N "sp|Q9P035|HACD3_HUMAN,sp|P82930|RT34_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN,tr|C9JJ19|C9JJ19_HUMAN,tr|H3BMZ1|H3BMZ1_HUMAN,tr|H3BRL8|H3BRL8_HUMAN" 7 811.528 1.14 39922 15972 2 811.52977 406.7713 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 9.75 3279.1 - 3.26E+06 - - - 2.2143 - 1.649 0.182 - 199.2 1 1 0 0.0018 7 0 0 0 4.82E+08 4.24E+08 - - - 1.9695 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.15975.15975.2 0.0552 14-Jun K.ELPTVVFR[166.11].A sp|Q9BVP2|GNL3_HUMAN 1 969.5523 0.91 39923 15975 2 969.554982 485.7834 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 6.1 3279.5 - 3.86E+06 - - - 2.7796 - 1.333 0.26 - 124.4 1 2 0 0.0027 8 0 0 0 1.33E+08 1.46E+08 - - - 1.8274 0.9167 230117_WJC_METTL3_WT_vs_EV_F05.15982.15982.2 3.7 16-May K.RLSFAVPFR.E sp|P78527|PRKDC_HUMAN 1 1091.624 999 39928 15982 2 1091.623571 546.8193 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 12 3280.4 - 293996 - - - -0.3921 - 1.127 0.037 - 72.6 3 2 0 -0.0004 9 0 0 0 8.92E+06 0.00E+00 - - - -0.5531 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.15984.15984.2 0.000581 14-Sep K.FC[160.03]ELLIGR.G "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1006.527 999 39930 15984 2 1006.530223 504.2708 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.99 3280.6 - 505117 - - - 3.215 - 1.845 0.481 - 347 1 2 0 0.0032 8 0 0 0 1.34E+08 0.00E+00 - - - 4.4399 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.15989.15989.3 0.0161 Dec-36 K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 9.74 39932 15989 3 1149.583503 384.2012 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3281.2 - 506667 - - - 1.4301 - 1.906 0.361 - 265.6 1 2 0 0.0016 10 0 0 0 1.43E+07 1.47E+06 - - - 4.448 0.9791 230117_WJC_METTL3_WT_vs_EV_F05.15993.15993.2 3.42 12-Jun K.VFGIQLK.E "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN" 3 803.4905 6.44 39934 15993 2 803.492564 402.7525 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 8.72 3281.7 - 4.08E+06 - - - 2.5377 - 1.163 0.092 - 104.8 1 2 0 0.002 7 0 0 0 7.32E+07 1.14E+07 - - - 0.1983 0.998 230117_WJC_METTL3_WT_vs_EV_F05.15997.15997.2 0.203 12-Aug K.YGAFLLR[166.11].R "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 848.4784 1.08 39936 15997 2 848.481084 425.2465 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.75 3282.2 - 810980 - - - 3.1704 - 1.73 0.219 - 263.9 1 2 0 0.0027 7 0 0 0 3.51E+07 3.25E+07 - - - 2.3944 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.16002.16002.2 0.208 14-Jul K.ELPTVVFR.A sp|Q9BVP2|GNL3_HUMAN 1 959.544 0.92 39939 16002 2 959.546548 480.7793 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 6.1 3282.9 - 2.95E+06 - - - 2.6377 - 1.244 0.314 - 191.3 1 2 0 0.0025 8 0 0 0 1.32E+08 1.44E+08 - - - 2.0179 0.9188 230117_WJC_METTL3_WT_vs_EV_F05.16006.16006.2 4.72 14-May R.ILVIGLSR[166.11].E sp|Q8N201|INT1_HUMAN 1 879.5781 1.25 39941 16006 2 879.579165 440.7963 Integrator complex subunit 1 OS=Homo sapiens OX=9606 GN=INTS1 PE=1 SV=2 9.75 3283.3 - 250046 - - - 1.2017 - 1.143 0.003 - 55.3 7 2 0 0.0011 8 0 0 0 8.32E+06 6.63E+06 - - - -0.9116 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.16014.16014.2 0.149 16-Aug K.LYENLGFVR[166.11].D "sp|Q147X3|NAA30_HUMAN,tr|J3KNC2|J3KNC2_HUMAN,tr|B4DK34|B4DK34_HUMAN" 3 1119.5952 2.8 39945 16014 2 1119.59708 560.8049 N-alpha-acetyltransferase 30 OS=Homo sapiens OX=9606 GN=NAA30 PE=1 SV=1 6 3284.4 - 91435.5 - - - 1.6658 - 1.449 0.237 - 138 1 2 0 0.0019 9 0 0 0 1.06E+07 3.77E+06 - - - 1.8639 0.9963 230117_WJC_METTL3_WT_vs_EV_F05.16017.16017.2 0.136 12-Aug K.MIFVGIK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 806.4724 2.19 39946 16017 2 806.475229 404.2435 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 8.5 3284.8 - 1.61E+06 - - - 3.4682 - 1.389 0.257 - 279.2 1 2 0 0.0028 7 0 0 0 3.24E+07 1.48E+07 - - - 1.9795 0.9694 230117_WJC_METTL3_WT_vs_EV_F05.16021.16021.2 5.7 14-Jul R.LLAMAVIR[166.11].K sp|Q96EK4|THA11_HUMAN 1 895.5553 0.19 39949 16021 2 895.557472 448.7849 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 9.75 3285.3 - 319548 - - - 2.4655 - 1.245 0.029 - 114.6 1 2 0 0.0022 8 0 0 0 1.11E+07 5.80E+07 - - - -0.0846 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16027.16027.2 0.0297 20-Nov K.LLLIGDSGVGK.T "sp|P61006|RAB8A_HUMAN,sp|P51153|RAB13_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P59190|RAB15_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YL94|H0YL94_HUMAN,tr|A0A2R8YDI9|A0A2R8YDI9_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|G3V196|G3V196_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H0YLJ8|H0YLJ8_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN,tr|F5H157|F5H157_HUMAN" 19 1070.6336 1.48 39952 16027 2 1070.636226 536.3241 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.84 3286.1 - 4.57E+06 - - - 2.4901 - 2.355 0.386 - 368.6 1 2 0 0.0027 11 0 0 0 2.58E+08 1.74E+08 - - - 4.2083 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.16032.16032.2 0.0301 16-Sep R.IVATLPYIK[136.11].Q "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1024.6412 1.26 39955 16032 2 1024.642761 513.3279 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 8.59 3286.7 - 2.52E+06 - - - 1.5059 - 1.722 0.221 - 165.7 1 2 0 0.0015 9 0 0 0 1.23E+08 9.76E+07 - - - 2.2452 0.9906 230117_WJC_METTL3_WT_vs_EV_F05.16034.16034.2 0.689 12-May K.IIAALFK[136.11].A "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 782.5146 1.65 39957 16034 2 782.515593 392.2646 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3287 - 542106 - - - 1.3188 - 1.273 0.096 - 59 1 2 0 0.001 7 0 0 0 1.99E+07 1.20E+07 - - - 0.5145 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.16036.16036.2 0.0101 14-Jul R.LSYTQLLR.R "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 992.5655 1.55 39959 16036 2 992.569134 497.29 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.75 3287.2 - 475407 - - - 3.6804 - 1.619 0.356 - 118 1 2 0 0.0037 8 0 0 0 4.24E+06 2.74E+06 - - - 3.1224 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.16042.16042.2 0.504 12-Aug K.YGAFLLR.R "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 838.4701 1.09 39963 16042 2 838.471949 420.2423 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.75 3287.9 - 698472 - - - 2.1766 - 1.653 0.225 - 229.3 1 2 0 0.0018 7 0 0 0 3.54E+07 3.25E+07 - - - 2.2948 0.9295 230117_WJC_METTL3_WT_vs_EV_F05.16044.16044.2 0.0557 14-Aug R.PLELSDFR[166.11].M "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 985.5108 1.74 39965 16044 2 985.513213 493.7627 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.37 3288.1 - 270034 - - - 2.4322 - 1.594 0.313 - 235 1 1 0 0.0024 8 0 0 0 3.22E+07 1.85E+07 - - - 2.7582 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.16051.16051.2 0.18 16-Sep K.LTLLQVASR.Q sp|O95239|KIF4A_HUMAN 1 999.6077 1.85 39970 16051 2 999.609666 500.8111 Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3 9.75 3288.9 - 897163 - - - 1.9868 - 1.89 0.249 - 234.7 1 2 0 0.002 9 0 0 0 2.56E+07 1.38E+07 - - - 2.7211 0.9949 230117_WJC_METTL3_WT_vs_EV_F05.16055.16055.2 0.0136 12-Jun R.EYFYGFR.G "sp|Q92989|CLP1_HUMAN,tr|E9PL17|E9PL17_HUMAN" 2 980.4392 3.66 39974 16055 2 980.439071 491.2269 Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1 6.1 3289.4 - 151026 - - - -0.1499 - 1.223 0.224 - 105.8 1 2 0 -0.0001 7 0 0 0 3.00E+06 8.18E+05 - - - 1.3333 0.9847 230117_WJC_METTL3_WT_vs_EV_F05.16062.16062.2 3.58 14-Sep K.GGLGLILK.R "sp|O75832|PSD10_HUMAN,tr|B1AJY5|B1AJY5_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 3 769.5062 1.65 39978 16062 2 769.508079 385.7604 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 8.75 3290.5 - 572605 - - - 2.4743 - 1.27 0.085 - 197.2 1 2 0 0.0019 8 0 0 0 6.75E+07 4.08E+07 - - - 0.3891 0.9083 230117_WJC_METTL3_WT_vs_EV_F05.16064.16064.2 0.00836 18-Jul R.MITQTSITPY.L "sp|P29558|RBMS1_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN" 3 1153.5689 - 39980 16064 2 1153.572137 577.7917 "RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1 PE=1 SV=3" 5.27 3290.7 - 520847 - - - 2.7965 - 1.177 0.428 - 114.7 1 1 0 0.0032 10 0 0 0 - - - - - 2.6561 1 230117_WJC_METTL3_WT_vs_EV_F05.16065.16065.2 4.45E-06 20-Oct K.NSLESYAFNMK.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1302.5914 44.69 39981 16065 2 1302.595915 652.303 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6 3290.8 - 154358 - - - 3.437 - 2.247 0.517 - 465.6 1 2 0 0.0045 11 0 0 0 1.03E+07 2.30E+05 - - - 5.0483 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.16070.16070.2 0.00381 16-Aug K.IYPVGYFTK.E "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 1086.575 7.57 39985 16070 2 1086.577182 544.2948 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.5 3291.5 - 1.57E+06 - - - 2.0238 - 1.461 0.361 - 207.8 1 2 0 0.0022 9 0 0 0 7.82E+07 1.03E+07 - - - 2.8035 0.9771 230117_WJC_METTL3_WT_vs_EV_F05.16072.16072.2 2.03 14-Jun R.LISLPLSR[166.11].L "sp|Q9NRG0|CHRC1_HUMAN,tr|E5RGS9|E5RGS9_HUMAN" 2 907.573 1.9 39986 16072 2 907.575071 454.7938 Chromatin accessibility complex protein 1 OS=Homo sapiens OX=9606 GN=CHRAC1 PE=1 SV=1 9.75 3291.7 - 797627 - - - 2.2566 - 1.187 0.066 - 84.4 1 2 0 0.002 8 0 0 0 5.49E+07 2.89E+07 - - - 0.0449 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.16076.16076.2 0.00117 14-Jul R.GFVLYPVK.Y sp|P62487|RPB7_HUMAN 1 921.5324 0.01 39990 16076 2 921.534105 461.7735 DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1 8.59 3292 - 514026 - - - 1.861 - 1.254 0.293 - 158.1 1 2 0 0.0017 8 0 0 0 1.32E+07 1.27E+09 - - - 1.8872 0.9964 230117_WJC_METTL3_WT_vs_EV_F05.16078.16078.2 0.163 12-Jul R.LSAIFLR.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 818.5014 1.72 39992 16078 2 818.503326 410.258 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3292.2 - 367476 - - - 2.3238 - 1.576 0.127 - 155.2 1 2 0 0.0019 7 0 0 0 3.73E+07 2.17E+07 - - - 1.4198 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.16082.16082.2 9.45E-05 18-Oct K.AMTILLEEAK.A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1117.6053 2.06 39996 16082 2 1117.605502 559.8099 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3292.7 - 179760 - - - 0.1834 - 2.116 0.351 - 349.6 1 2 0 0.0002 10 0 0 0 3.34E+07 1.62E+07 - - - 3.7256 0.9938 230117_WJC_METTL3_WT_vs_EV_F05.16083.16083.3 0.0704 Jul-36 K.DR[166.11]PFFPGLVK[136.11].Y "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN" 5 1192.6723 0.88 39997 16083 3 1192.673718 398.5647 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 8.75 3292.8 - 144798 - - - 1.1478 - 1.395 0.208 - 46.9 1 2 0 0.0014 10 0 0 0 2.48E+06 2.81E+06 - - - 1.8308 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.16089.16089.2 2.31 12-Aug R.LSAIFLR[166.11].L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 828.5097 1.78 40002 16089 2 828.511968 415.2621 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3293.5 - 1.18E+06 - - - 2.7447 - 1.922 0.111 - 171.7 1 2 0 0.0023 7 0 0 0 3.72E+07 2.08E+07 - - - 1.9304 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16090.16090.2 0.623 18-Oct K.AMTILLEEAK[136.11].A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1125.6195 2.06 40003 16090 2 1125.62153 563.817 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3293.7 - 375139 - - - 1.8061 - 2.13 0.326 - 337.7 1 2 0 0.002 10 0 0 0 3.35E+07 1.63E+07 - - - 3.5588 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16099.16099.2 0.00261 16-Sep R.FDDPLLGPR[166.11].R "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 8 1038.5374 0.84 40010 16099 2 1038.537339 520.276 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.21 3294.8 - 554548 - - - -0.025 - 1.867 0.451 - 250 1 2 0 0 9 0 0 0 5.87E+07 6.97E+07 - - - 4.1783 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.16100.16100.3 6.46E-05 13/52 K.NVALLSQLYHSPAR[166.11].R sp|Q15717|ELAV1_HUMAN 1 1577.8553 1.09 40011 16100 3 1577.857979 526.9591 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.75 3294.9 - 384114 - - - 1.6687 - 2.509 0.435 - 234.1 1 2 0 0.0026 14 0 0 0 4.74E+06 4.33E+06 - - - 5.8337 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.16101.16101.2 0.116 12-Jun R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 70.6 40012 16101 2 806.392553 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 3295 - 378402 - - - 0.3547 - 1.368 0.264 - 108.5 1 2 0 0.0003 7 0 0 0 4.81E+07 6.81E+05 - - - 1.9837 0.9964 230117_WJC_METTL3_WT_vs_EV_F05.16103.16103.2 0.00136 20-Aug K.C[160.03]ILVASPGFVR.E sp|Q9BRX2|PELO_HUMAN 1 1217.6591 3.6 40014 16103 2 1217.663399 609.8368 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 8.25 3295.3 - 309712 - - - 3.5601 - 1.646 0.226 - 185.8 1 2 0 0.0043 11 0 0 0 1.48E+07 4.10E+06 - - - 2.057 0.997 230117_WJC_METTL3_WT_vs_EV_F05.16109.16109.2 0.0397 16-Oct K.VVDVLDSIK[136.11].T sp|P00918|CAH2_HUMAN 1 994.579 0.9 40018 16109 2 994.583357 498.2968 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.21 3296.1 - 637327 - - - 4.3687 - 2.09 0.227 - 273.9 1 2 0 0.0043 9 0 0 0 2.17E+07 2.40E+07 - - - 2.8489 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.16110.16110.3 1.23E-06 16/52 K.NVALLSQLYHSPAR.R sp|Q15717|ELAV1_HUMAN 1 1567.8471 1.11 40019 16110 3 1567.85457 523.623 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.75 3296.3 - 352552 - - - 4.7798 - 2.878 0.511 - 281.3 1 2 0 0.0075 14 0 0 0 4.74E+06 4.28E+06 - - - 7.0443 0.9844 230117_WJC_METTL3_WT_vs_EV_F05.16112.16112.2 0.997 14-Jul K.LFIGNLPR.E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 928.5494 2.13 40020 16112 2 928.554315 465.282 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3296.5 - 4.72E+07 - - - 5.2534 - 1.384 0.236 - 201.8 1 2 0 0.0049 8 0 0 0 2.57E+09 1.21E+09 - - - 1.7627 0.9818 230117_WJC_METTL3_WT_vs_EV_F05.16115.16115.2 0.0741 12-Jul R.NLVLLVR.E sp|Q9H2W6|RM46_HUMAN 1 825.5436 1.01 40022 16115 2 825.545015 413.7791 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 9.75 3296.8 - 1.97E+06 - - - 1.6862 - 1.386 0.001 - 195.3 1 2 0 0.0014 7 0 0 0 4.65E+07 4.60E+07 - - - 0.0822 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.16118.16118.2 0.0118 16-Oct K.VVDVLDSIK.T sp|P00918|CAH2_HUMAN 1 986.5648 0.89 40025 16118 2 986.565734 494.2897 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.21 3297 - 1.11E+06 - - - 0.9346 - 1.608 0.327 - 235.9 1 2 0 0.0009 9 0 0 0 2.18E+07 2.43E+07 - - - 2.8301 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.16123.16123.2 1.12 12-Aug K.ILPDILK.K "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 810.5215 2.06 40028 16123 2 810.5229 406.268 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 3297.5 - 3.48E+06 - - - 1.7384 - 1.547 0.12 - 179.7 1 2 0 0.0014 7 0 0 0 8.80E+07 4.28E+07 - - - 1.3094 0.8851 230117_WJC_METTL3_WT_vs_EV_F05.16124.16124.2 0.21 14-Aug F.AFLWAGGR.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A1W2PNG3|A0A1W2PNG3_HUMAN" 12 876.4606 1.23 40029 16124 2 876.462394 439.2376 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.79 3297.6 - 1.83E+06 - - - 2.0218 - 1.557 0.221 - 246 1 1 0 0.0018 8 0 0 0 1.74E+09 1.41E+09 - - - 2.0081 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.16128.16128.2 0.262 14-Aug M.VLLTMIAR.V sp|O75396|SC22B_HUMAN 1 915.5576 1.16 40033 16128 2 915.559292 458.7861 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 9.72 3297.8 - 1.98E+06 - - - 1.8928 - 1.582 0.335 - 252.6 1 2 0 0.0017 8 0 0 0 7.03E+07 6.06E+07 - - - 2.8982 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.16129.16129.2 0.3 18-Oct K.LLADELISPK[136.11].D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1105.6474 1.14 40034 16129 2 1105.648149 553.831 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3297.9 - 1.63E+06 - - - 0.6539 - 1.874 0.288 - 232.1 1 2 0 0.0007 10 0 0 0 6.14E+07 5.37E+07 - - - 2.9211 0.9948 230117_WJC_METTL3_WT_vs_EV_F05.16134.16134.2 0.141 16-Aug R.IVLNGIDLK.A sp|O15294|OGT1_HUMAN 1 983.6015 2.02 40037 16134 2 983.604053 492.808 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 5.84 3298.5 - 1.71E+06 - - - 2.563 - 1.537 0.126 - 114.4 1 2 0 0.0025 9 0 0 0 2.43E+07 1.20E+07 - - - 1.2144 0.991 230117_WJC_METTL3_WT_vs_EV_F05.16137.16137.2 0.0563 20-Aug K.C[160.03]ILVASPGFVR[166.11].E sp|Q9BRX2|PELO_HUMAN 1 1227.6673 3.6 40040 16137 2 1227.666024 614.8409 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 8.25 3298.9 - 281516 - - - -1.0671 - 1.653 0.125 - 197.9 1 2 0 -0.0013 11 0 0 0 1.48E+07 4.10E+06 - - - 1.3235 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.16141.16141.2 0.228 12-Jul K.MFEFYER.V "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 13 1020.4375 2.09 40042 16141 2 1020.440374 511.226 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3299.3 - 1.15E+06 - - - 2.8135 - 1.328 0.212 - 217.1 1 2 0 0.0029 7 0 0 0 2.06E+07 9.83E+06 - - - 1.5048 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.16143.16143.2 0.00124 16-Aug K.AFIGFEGVK.G sp|P15924|DESP_HUMAN 1 966.5175 1.81 40044 16143 2 966.518543 484.266 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.05 3299.5 - 1.10E+06 - - - 1.1122 - 1.671 0.505 - 186 1 2 0 0.0011 9 0 0 0 6.28E+07 3.47E+07 - - - 4.256 0.8753 230117_WJC_METTL3_WT_vs_EV_F05.16146.16146.2 0.000608 14-Jul K.FYSFALDK.T sp|Q96T58|MINT_HUMAN 1 989.4858 0.92 40047 16146 2 990.488523 495.7502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.83 3299.7 - 549900 - - - 1013.3435 - 1.24 0.459 - 97.5 1 2 0 1.0027 8 0 0 0 2.99E+07 3.24E+07 - - - 2.7651 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.16150.16150.2 0.026 18-Oct K.LLADELISPK.D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1097.6332 1.14 40049 16150 2 1097.635785 549.8239 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3300.2 - 876895 - - - 2.3314 - 2.209 0.321 - 268.5 1 2 0 0.0026 10 0 0 0 6.14E+07 5.37E+07 - - - 3.6233 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.16156.16156.2 0.0394 20-Oct K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 0.93 40054 16156 2 1235.762586 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3301 - 4.44E+06 - - - 1.9648 - 2.038 0.284 - 280.3 1 2 0 0.0024 11 0 0 0 8.45E+07 9.07E+07 - - - 3.0639 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16158.16158.2 0.000762 18-Oct R.LTPLQLEIQR[166.11].V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1219.7164 1.17 40055 16158 2 1219.71804 610.8655 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 3301.2 - 615662 - - - 1.3511 - 1.816 0.397 - 445.9 1 2 0 0.0016 10 0 0 0 3.27E+07 2.78E+07 - - - 3.6381 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.16161.16161.2 0.0152 20-Sep K.LLDSITVPVAR[166.11].A sp|O00203|AP3B1_HUMAN 1 1192.7055 1.55 40058 16161 2 1192.703114 597.36 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3301.6 - 176160 - - - -1.9946 - 2.009 0.336 - 177.2 1 2 0 -0.0024 11 0 0 0 2.08E+07 1.34E+07 - - - 3.4092 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.16164.16164.2 0.0128 18-Oct R.LTPLQLEIQR.V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1209.7081 1.17 40059 16164 2 1209.709647 605.8613 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 3302 - 693135 - - - 1.2606 - 1.682 0.347 - 496.3 1 2 0 0.0015 10 0 0 0 3.27E+07 2.78E+07 - - - 3.0549 0.999 230117_WJC_METTL3_WT_vs_EV_F05.16166.16166.2 0.294 20-Oct K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.15 40060 16166 2 1245.770343 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3302.2 - 2.24E+06 - - - 1.5372 - 1.502 0.298 - 187.6 1 2 0 0.0019 11 0 0 0 5.49E+07 4.78E+07 - - - 2.3419 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.16182.16182.2 0.0158 14-Aug R.LLNTFLER.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 8 1004.5655 1.37 40070 16182 2 1004.566718 503.29 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3304 - 714035 - - - 1.2314 - 1.852 0.299 - 202.8 1 2 0 0.0012 8 0 0 0 1.41E+08 1.03E+08 - - - 3.1077 0.9956 230117_WJC_METTL3_WT_vs_EV_F05.16184.16184.2 0.292 12-Jun K.LFQLYPR.N sp|Q8IXM3|RM41_HUMAN 1 935.5229 1.16 40072 16184 2 935.524321 468.7687 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 8.75 3304.1 - 600326 - - - 1.5318 - 1.259 0.177 - 107.3 1 2 0 0.0014 7 0 0 0 6.89E+07 5.96E+07 - - - 1.0776 0.9817 230117_WJC_METTL3_WT_vs_EV_F05.16189.16189.2 2.4 12-May R.ALVELLR.E "sp|Q92974|ARHG2_HUMAN,tr|A0A5F9ZI21|A0A5F9ZI21_HUMAN,tr|V9GYM8|V9GYM8_HUMAN" 3 812.512 1.48 40075 16189 2 812.512431 407.2633 Rho guanine nucleotide exchange factor 2 OS=Homo sapiens OX=9606 GN=ARHGEF2 PE=1 SV=4 6.05 3304.6 - 1.86E+06 - - - 0.544 - 1.028 0.139 - 62.6 1 2 0 0.0004 7 0 0 0 3.52E+07 2.38E+07 - - - 0.155 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.16190.16190.2 0.00984 20-Oct K.LLDSITVPVAR.A sp|O00203|AP3B1_HUMAN 1 1182.6972 1.55 40076 16190 2 1182.698651 592.3559 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3304.7 - 633477 - - - 1.2074 - 2.17 0.39 - 326 1 2 0 0.0014 11 0 0 0 2.08E+07 1.34E+07 - - - 4.0169 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.16193.16193.2 0.548 14-Jun R.LMGLEALK.S "sp|P48643|TCPE_HUMAN,tr|D6RIZ7|D6RIZ7_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0Y914|H0Y914_HUMAN" 4 873.4994 5.67 40077 16193 2 873.501243 437.757 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 3305.1 - 2.92E+07 - - - 2.1385 - 1.29 0.233 - 111.7 1 2 0 0.0019 8 0 0 0 2.05E+09 3.62E+08 - - - 1.5293 0.9515 230117_WJC_METTL3_WT_vs_EV_F05.16194.16194.2 0.00169 22-Dec R.GLLQDDAHPTLV.T "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1277.6616 - 40078 16194 2 1277.661588 639.8381 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3305.2 - 278180 - - - 0.0172 - 1.964 0.352 - 218.1 1 1 0 0 12 0 0 0 - - - - - 3.4169 0.9907 230117_WJC_METTL3_WT_vs_EV_F05.16197.16197.2 0.114 12-Jun K.LMVIFSK.V "sp|Q9BRK5|CAB45_HUMAN,tr|A0A5F9UJX7|A0A5F9UJX7_HUMAN,tr|A0A5F9UP49|A0A5F9UP49_HUMAN,tr|G3V1E2|G3V1E2_HUMAN,tr|H0Y3T6|H0Y3T6_HUMAN" 5 836.483 0.38 40081 16197 2 836.483748 419.2488 45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1 8.75 3305.5 - 478634 - - - 0.8978 - 1.555 0.033 - 114.8 2 2 0 0.0008 7 0 0 0 2.30E+07 6.09E+07 - - - 0.5489 0.997 230117_WJC_METTL3_WT_vs_EV_F05.16198.16198.2 0.00113 18-Sep K.LGLTEDQFIR.T "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1190.6295 3.47 40082 16198 2 1190.626889 596.322 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.37 3305.6 - 330059 - - - -2.2249 - 1.602 0.388 - 190.5 1 2 0 -0.0026 10 0 0 0 1.39E+07 4.02E+06 - - - 3.2213 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.16205.16205.2 0.0245 13/22 K.LGALTAEEIALK.M sp|Q13601|KRR1_HUMAN 1 1227.7075 1.22 40086 16205 2 1227.70931 614.861 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3306.4 - 1.27E+06 - - - 1.5118 - 2.244 0.447 - 520.9 1 2 0 0.0019 12 0 0 0 1.09E+08 8.95E+07 - - - 4.4686 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.16206.16206.2 0.0413 18-Aug K.IPVSGPFLVK.T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1055.6379 1.28 40087 16206 2 1055.636804 528.8262 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3306.6 - 443478 - - - -1.0553 - 1.565 0.262 - 112.6 1 2 0 -0.0011 10 0 0 0 1.59E+08 1.25E+08 - - - 2.226 0.9863 230117_WJC_METTL3_WT_vs_EV_F05.16207.16207.2 0.000261 22-Oct R.VFASELNAGIIK[136.11].T "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1268.722 1.34 40088 16207 2 1268.731653 635.3683 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.97 3306.7 - 296201 - - - 7.6179 - 1.767 0.419 - 225.2 1 2 0 0.0097 12 0 0 0 1.25E+07 9.33E+06 - - - 3.6306 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.16212.16212.2 0.0103 16-Aug R.IGFGSFVEK.T "sp|P05556|ITB1_HUMAN,sp|P18564|ITB6_HUMAN,tr|A0A7I2V2F9|A0A7I2V2F9_HUMAN,tr|A0A087WXP3|A0A087WXP3_HUMAN,tr|A0A7I2V5T3|A0A7I2V5T3_HUMAN,tr|H7C4K3|H7C4K3_HUMAN,tr|E7EUI6|E7EUI6_HUMAN,tr|E9PEE8|E9PEE8_HUMAN,tr|A0A7I2V5Z8|A0A7I2V5Z8_HUMAN,tr|A0A7I2V348|A0A7I2V348_HUMAN,tr|C9JPK5|C9JPK5_HUMAN" 11 982.5124 2.23 40091 16212 2 982.513136 492.2635 Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1 PE=1 SV=2 6 3307.4 - 484662 - - - 0.7664 - 1.457 0.376 - 117.5 1 2 0 0.0008 9 0 0 0 1.60E+07 7.16E+06 - - - 2.9068 0.9897 230117_WJC_METTL3_WT_vs_EV_F05.16216.16216.2 5.51 12-Jul K.DVLLPLK.S sp|Q9Y385|UB2J1_HUMAN 1 796.5058 1.33 40092 16216 2 796.509166 399.2602 Ubiquitin-conjugating enzyme E2 J1 OS=Homo sapiens OX=9606 GN=UBE2J1 PE=1 SV=2 5.84 3307.9 - 120942 - - - 4.1745 - 1.476 0.165 - 212.6 1 2 0 0.0033 7 0 0 0 1.11E+07 8.33E+06 - - - 1.4923 0.9906 230117_WJC_METTL3_WT_vs_EV_F05.16218.16218.2 0.000506 22-Sep K.LGALTAEEIALK[136.11].M sp|Q13601|KRR1_HUMAN 1 1235.7217 1.21 40094 16218 2 1235.715812 618.8681 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3308.1 - 674828 - - - -4.7276 - 2.201 0.375 - 223.5 1 2 0 -0.0058 12 0 0 0 1.08E+08 8.95E+07 - - - 3.8847 0.9347 230117_WJC_METTL3_WT_vs_EV_F05.16226.16226.2 0.0608 18-Aug F.LLVGTQIDLR.D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1126.671 1.57 40098 16226 2 1126.671531 564.3428 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.84 3309.1 - 563603 - - - 0.4633 - 1.753 0.286 - 205.9 1 1 0 0.0005 10 0 0 0 1.10E+07 7.00E+06 - - - 2.7201 0.9959 230117_WJC_METTL3_WT_vs_EV_F05.16229.16229.2 0.698 12-Jun K.LIIFDAR.Q "sp|Q13613|MTMR1_HUMAN,tr|Q8NEC6|Q8NEC6_HUMAN,tr|F8WA39|F8WA39_HUMAN,tr|H0YDX3|H0YDX3_HUMAN" 4 846.4963 3.67 40099 16229 2 846.496561 424.2554 Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4 5.84 3309.5 - 1.08E+06 - - - 0.2623 - 1.348 0.183 - 127.3 1 2 0 0.0002 7 0 0 0 7.48E+07 2.04E+07 - - - 1.3388 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.16230.16230.2 0.0272 18-Sep K.IPVSGPFLVK[136.11].T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1063.6521 1.28 40100 16230 2 1063.651885 532.8333 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3309.6 - 1.24E+06 - - - -0.2191 - 1.547 0.338 - 190 1 2 0 -0.0002 10 0 0 0 1.59E+08 1.25E+08 - - - 2.7553 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.16240.16240.2 0.0305 16-Nov R.IGLINDMVR[166.11].F sp|Q14152|EIF3A_HUMAN 1 1039.5724 1.27 40105 16240 2 1039.574846 520.7935 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.84 3310.9 - 515371 - - - 2.3808 - 1.738 0.223 - 345.2 1 2 0 0.0025 9 0 0 0 7.62E+07 5.98E+07 - - - 2.2864 0.9611 230117_WJC_METTL3_WT_vs_EV_F05.16241.16241.2 3.85 12-Jun K.LIIFDAR[166.11].Q "sp|Q13613|MTMR1_HUMAN,tr|Q8NEC6|Q8NEC6_HUMAN,tr|F8WA39|F8WA39_HUMAN,tr|H0YDX3|H0YDX3_HUMAN" 4 856.5046 4.11 40106 16241 2 856.504841 429.2596 Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4 5.84 3311 - 284165 - - - 0.2709 - 1.072 0.063 - 114.7 1 2 0 0.0002 7 0 0 0 7.29E+07 1.77E+07 - - - -0.2735 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.16242.16242.2 0.0448 16-Jul R.SAVYPLLYR.D "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H7C184|H7C184_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1080.5968 2.02 40107 16242 2 1080.59919 541.3057 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 8.31 3311.2 - 261567 - - - 2.2293 - 1.798 0.214 - 201.9 1 2 0 0.0024 9 0 0 0 9.80E+06 4.85E+06 - - - 2.3181 0.9547 230117_WJC_METTL3_WT_vs_EV_F05.16246.16246.2 1.23 12-Jul K.LMFEELR[166.11].N sp|Q9Y3I0|RTCB_HUMAN 1 946.4822 1.04 40109 16246 2 946.482038 474.2484 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.53 3311.6 - 5.03E+06 - - - -0.1278 - 1.04 0.08 - 107.3 1 2 0 -0.0001 7 0 0 0 5.44E+07 5.20E+07 - - - -0.2439 0.9641 230117_WJC_METTL3_WT_vs_EV_F05.16248.16248.2 0.936 16-May K.VILTSPLIR[166.11].D sp|Q96SI9|STRBP_HUMAN 1 1020.6571 2.01 40111 16248 2 1020.658821 511.3358 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 9.72 3311.7 - 1.51E+06 - - - 1.6989 - 1.113 0.057 - 56.5 2 2 0 0.0017 9 0 0 0 3.66E+07 1.82E+07 - - - -0.3633 1 230117_WJC_METTL3_WT_vs_EV_F05.16258.16258.2 2.94E-06 20-Oct R.LLTGVEYVVGR.K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1204.6816 1.71 40119 16258 2 1204.687611 603.3481 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3312.9 - 0 - - - 5.0121 - 2.215 0.53 - 301.9 1 2 0 0.006 11 0 0 0 2.89E+07 1.68E+07 - - - 5.105 1 230117_WJC_METTL3_WT_vs_EV_F05.16262.16262.2 0.00127 13/22 K.VLVALASEELAK[136.11].G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1249.7373 1.65 40121 16262 2 1249.745068 625.8759 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.53 3313.4 - 703287 - - - 6.2125 - 2.679 0.473 - 606.1 1 2 0 0.0078 12 0 0 0 4.09E+07 2.48E+07 - - - 5.125 0.9942 230117_WJC_METTL3_WT_vs_EV_F05.16263.16263.2 0.0153 16-Aug R.LFGTTVTFK[136.11].F "sp|Q15904|VAS1_HUMAN,tr|A0A0C4DGX8|A0A0C4DGX8_HUMAN" 2 1020.5735 4.55 40122 16263 2 1020.577315 511.294 V-type proton ATPase subunit S1 OS=Homo sapiens OX=9606 GN=ATP6AP1 PE=1 SV=2 8.75 3313.5 - 1.09E+06 - - - 3.7058 - 1.303 0.257 - 120.6 1 2 0 0.0038 9 0 0 0 1.15E+08 2.53E+07 - - - 1.7037 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.16267.16267.2 0.00139 22-Dec K.VLVALASEELAK.G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1241.7231 1.65 40124 16267 2 1241.724819 621.8688 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.53 3314 - 1.08E+06 - - - 1.3811 - 2.221 0.43 - 366.6 1 2 0 0.0017 12 0 0 0 4.09E+07 2.48E+07 - - - 4.316 0.9942 230117_WJC_METTL3_WT_vs_EV_F05.16271.16271.2 0.693 12-Jul K.LWYTLDR.A sp|P00387|NB5R3_HUMAN 1 965.4971 2 40128 16271 2 965.497017 483.7558 NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3 5.84 3314.5 - 626291 - - - -0.0518 - 1.44 0.133 - 200.2 1 2 0 -0.0001 7 0 0 0 5.29E+07 2.64E+07 - - - 1.1787 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.16274.16274.2 0.364 16-Sep K.ALLSTVLSR.S "sp|Q5H9F3|BCORL_HUMAN,tr|H7C4B2|H7C4B2_HUMAN" 2 958.5811 2.98 40131 16274 2 958.580928 480.2978 BCL-6 corepressor-like protein 1 OS=Homo sapiens OX=9606 GN=BCORL1 PE=1 SV=1 9.79 3314.9 - 237690 - - - -0.2118 - 1.891 0.119 - 177.4 1 2 0 -0.0002 9 0 0 0 7.80E+06 2.62E+06 - - - 1.7631 1 230117_WJC_METTL3_WT_vs_EV_F05.16280.16280.2 2.32E-05 18-Dec K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 53.08 40135 16280 2 1146.630033 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3315.6 - 8.61E+06 - - - 1.3588 - 2.211 0.517 - 421 1 2 0 0.0016 10 0 0 0 2.16E+08 4.08E+06 - - - 5.0738 1 230117_WJC_METTL3_WT_vs_EV_F05.16282.16282.2 9.43E-05 20-Dec R.LLTGVEYVVGR[166.11].K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1214.6898 1.55 40137 16282 2 1214.690969 608.3522 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3315.9 - 691827 - - - 0.927 - 2.377 0.483 - 433.7 1 2 0 0.0011 11 0 0 0 2.62E+07 1.68E+07 - - - 4.9504 0.9941 230117_WJC_METTL3_WT_vs_EV_F05.16286.16286.2 0.151 12-Aug K.LWVLETK[136.11].E "sp|Q15061|WDR43_HUMAN,tr|C9JEE7|C9JEE7_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 3 895.5259 4.13 40139 16286 2 895.52482 448.7702 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3316.4 - 172093 - - - -1.1546 - 1.404 0.218 - 158.3 1 2 0 -0.001 7 0 0 0 2.13E+08 5.15E+07 - - - 1.726 0.9611 230117_WJC_METTL3_WT_vs_EV_F05.16288.16288.2 0.155 12-Jun R.EAYYWLR[166.11].H sp|P46977|STT3A_HUMAN 1 1009.4897 1.24 40140 16288 2 1009.491324 505.7521 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6.1 3316.6 - 743832 - - - 1.6216 - 1.144 0.015 - 142.1 1 2 0 0.0016 7 0 0 0 4.87E+07 3.94E+07 - - - -0.4225 0.9951 230117_WJC_METTL3_WT_vs_EV_F05.16293.16293.2 0.0306 12-Jun K.LWYTLDR[166.11].A sp|P00387|NB5R3_HUMAN 1 975.5053 1.98 40142 16293 2 975.505472 488.7599 NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3 5.84 3317.2 - 722678 - - - 0.1384 - 1.47 0.131 - 136.7 1 2 0 0.0001 7 0 0 0 5.20E+07 2.63E+07 - - - 1.2292 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.16295.16295.2 2.66 12-Sep M.LPLSLLK.T "sp|Q9Y4Z0|LSM4_HUMAN,sp|Q969I6|S38A4_HUMAN,tr|F8VQY9|F8VQY9_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 5 782.5266 22.87 40144 16295 2 782.526888 392.2706 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 8.75 3317.5 - 1.25E+06 - - - 0.3987 - 1.902 0.068 - 269.3 1 2 0 0.0003 7 0 0 0 2.36E+07 1.03E+06 - - - 1.5802 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16296.16296.2 0.172 20-Oct R.IDALLAVDPPR.A sp|P50219|MNX1_HUMAN 1 1178.6659 2.22 40145 16296 2 1178.668151 590.3402 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3317.6 - 545405 - - - 1.8903 - 2.283 0.301 - 303.6 1 2 0 0.0022 11 0 0 0 2.79E+07 1.26E+07 - - - 3.4966 0.9937 230117_WJC_METTL3_WT_vs_EV_F05.16299.16299.2 0.369 20-May K.VLEVPPVVYSR.Q "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1256.7129 0.66 40148 16299 2 1256.715792 629.3637 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 5.97 3318 - 298883 - - - 2.3227 - 1.356 0.192 - 72.5 5 2 0 0.0029 11 0 0 0 7.37E+06 1.11E+07 - - - 0.9698 0.9834 230117_WJC_METTL3_WT_vs_EV_F05.16305.16305.2 0.0565 12-Jul R.EAYYWLR.H sp|P46977|STT3A_HUMAN 1 999.4814 1.25 40152 16305 2 999.480426 500.748 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6.1 3318.6 - 1.40E+06 - - - -0.9915 - 1.312 0.123 - 253.4 1 2 0 -0.001 7 0 0 0 4.91E+07 3.94E+07 - - - 0.8096 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.16311.16311.2 0.016 18-Sep K.LVALAVIDEK[136.11].N sp|Q96JJ7|TMX3_HUMAN 1 1077.6525 1.81 40156 16311 2 1077.651898 539.8335 Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2 4.37 3319.3 - 646168 - - - -0.5688 - 2.189 0.361 - 137 1 2 0 -0.0006 10 0 0 0 1.65E+07 9.11E+06 - - - 3.894 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.16315.16315.2 0.015 20-Jul K.VLEVPPVVYSR[166.11].Q "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1266.7211 1.63 40160 16315 2 1266.723755 634.3678 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 5.97 3319.8 - 276366 - - - 2.062 - 1.56 0.138 - 148.9 1 2 0 0.0026 11 0 0 0 6.50E+06 3.98E+06 - - - 1.2624 0.9554 230117_WJC_METTL3_WT_vs_EV_F05.16319.16319.2 3.8 26-Jun R.IAGPAIPSVVAYPK.R "tr|A0A7I2YQF4|A0A7I2YQF4_HUMAN,tr|A0A7I2V549|A0A7I2V549_HUMAN,tr|A0A7I2V602|A0A7I2V602_HUMAN" 3 1381.7969 0.84 40162 16319 2 1381.797701 691.9057 Non-specific serine\threonine protein kinase OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=1 8.59 3320.4 - 616141 - - - 0.5529 - 1.155 0.022 - 93.6 1 2 0 0.0008 14 0 0 0 1.78E+07 2.11E+07 - - - -0.4351 0.9221 230117_WJC_METTL3_WT_vs_EV_F05.16320.16320.2 3.97 16-May K.YIIEELNVR[166.11].K "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1157.632 18.39 40163 16320 2 1157.632183 579.8233 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.53 3320.5 - 0 - - - 0.1633 - 1.048 0.035 - 38.9 2 2 0 0.0002 9 0 0 0 1.19E+08 6.47E+06 - - - -0.6994 0.9754 230117_WJC_METTL3_WT_vs_EV_F05.16330.16330.2 0.0302 20-Oct R.IDALLAVDPPR[166.11].A sp|P50219|MNX1_HUMAN 1 1188.6742 2.22 40171 16330 2 1188.682503 595.3444 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3321.6 - 704684 - - - 6.991 - 2.225 0.165 - 327 1 2 0 0.0083 11 0 0 0 2.75E+07 1.24E+07 - - - 2.4206 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16331.16331.2 8.26E-05 16-Oct R.SLFVVVGDR.G "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 990.5498 0.31 40172 16331 2 990.552408 496.2822 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.55 3321.8 - 699257 - - - 2.6016 - 2.143 0.415 - 310.2 1 2 0 0.0026 9 0 0 0 2.20E+07 7.18E+07 - - - 4.3105 1 230117_WJC_METTL3_WT_vs_EV_F05.16332.16332.2 2.83E-08 13/22 K.LNDLEEALQQAK.E sp|P35908|K22E_HUMAN 1 1370.7042 999 40173 16332 2 1370.701485 686.3594 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3321.9 - 532697 - - - -1.9508 - 2.77 0.532 - 760.1 1 2 0 -0.0027 12 0 0 0 4.30E+06 0.00E+00 - - - 5.6503 0.8663 230117_WJC_METTL3_WT_vs_EV_F05.16333.16333.2 3.8 20-Sep K.ALEEAGTILLR[166.11].A "sp|Q9H8Y5|ANKZ1_HUMAN,tr|B8ZZS4|B8ZZS4_HUMAN" 2 1194.6848 0.21 40174 16333 2 1194.691187 598.3497 Ankyrin repeat and zinc finger domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKZF1 PE=1 SV=1 4.53 3322 - 429464 - - - 5.3813 - 1.406 0.022 - 206.8 1 2 0 0.0064 11 0 0 0 5.71E+05 2.68E+06 - - - 0.1233 0.988 230117_WJC_METTL3_WT_vs_EV_F05.16345.16345.2 0.0935 16-Aug R.SLFVVVGDR[166.11].G "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 1000.5581 -1 40182 16345 2 1000.563553 501.2863 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.55 3323.4 - 1.89E+06 - - - 5.449 - 1.643 0.225 - 223.5 1 2 0 0.0055 9 0 0 0 0.00E+00 0.00E+00 - - - 2.1376 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.16346.16346.2 0.00222 16-Aug R.SPVYLTVLK[136.11].H "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1026.6205 1.37 40183 16346 2 1026.621488 514.3175 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 8.31 3323.5 - 645254 - - - 0.9789 - 1.706 0.353 - 183.4 1 2 0 0.001 9 0 0 0 2.03E+07 1.48E+07 - - - 3.1933 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.16347.16347.2 0.0468 12-Aug K.FVSFLGR[166.11].T "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 834.4627 1.39 40184 16347 2 834.462572 418.2386 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 9.75 3323.6 - 2.44E+06 - - - -0.2061 - 1.506 0.332 - 219.9 1 2 0 -0.0002 7 0 0 0 2.29E+08 1.65E+08 - - - 2.7905 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.16353.16353.2 0.522 12-Aug R.LFEGIIK.G "sp|O14936|CSKP_HUMAN,tr|A0A2U3TZM1|A0A2U3TZM1_HUMAN,tr|A0A2R8YFN5|A0A2R8YFN5_HUMAN,tr|A0A2R8YEK3|A0A2R8YEK3_HUMAN,tr|A0A2R8YE77|A0A2R8YE77_HUMAN,tr|A0A2R8Y6F8|A0A2R8Y6F8_HUMAN,tr|Q5JS79|Q5JS79_HUMAN,tr|A0A2R8Y3B3|A0A2R8Y3B3_HUMAN,tr|A0A2R8Y6D8|A0A2R8Y6D8_HUMAN,tr|A0A2U3TZN6|A0A2U3TZN6_HUMAN,tr|A0A2U3TZM4|A0A2U3TZM4_HUMAN,tr|A0A2R8YEJ7|A0A2R8YEJ7_HUMAN,tr|A0A7I2RJN6|A0A7I2RJN6_HUMAN" 13 818.4902 0.33 40188 16353 2 818.491435 410.2524 Peripheral plasma membrane protein CASK OS=Homo sapiens OX=9606 GN=CASK PE=1 SV=3 6 3324.3 - 1.56E+06 - - - 1.5199 - 1.759 0.139 - 148.4 1 2 0 0.0012 7 0 0 0 1.53E+07 4.69E+07 - - - 1.8567 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.16359.16359.2 5.62E-05 14-Aug K.VIFLENYR.V "sp|P06737|PYGL_HUMAN,sp|P11217|PYGM_HUMAN,sp|P11216|PYGB_HUMAN,tr|E9PK47|E9PK47_HUMAN,tr|H0Y4Z6|H0Y4Z6_HUMAN" 5 1052.5655 4.96 40192 16359 2 1052.567065 527.29 "Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL PE=1 SV=4" 5.97 3325 - 4.31E+06 - - - 1.5049 - 1.904 0.451 - 247.1 1 2 0 0.0016 8 0 0 0 7.02E+07 1.42E+07 - - - 4.3137 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.16361.16361.2 3.43 14-Aug R.ALDIPLVK[136.11].N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 875.5572 1.11 40194 16361 2 875.559842 438.7859 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3325.2 - 1.98E+06 - - - 3.07 - 1.508 0.248 - 197.2 1 2 0 0.0027 8 0 0 0 2.04E+07 1.84E+07 - - - 2.1108 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16362.16362.2 0.000694 16-Sep K.GPLMMYISK[136.11].M sp|P13639|EF2_HUMAN 1 1046.5384 0.12 40195 16362 2 1046.538571 524.2765 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 3325.3 - 1.25E+06 - - - 0.1538 - 1.816 0.452 - 332.8 1 2 0 0.0002 9 0 0 0 5.21E+07 4.22E+08 - - - 4.1055 1 230117_WJC_METTL3_WT_vs_EV_F05.16363.16363.2 0.000373 26-Dec F.LLIGGGTAAFAAAR.S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1287.7299 5.8 40196 16363 2 1287.732758 644.8722 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3325.4 - 306204 - - - 2.2039 - 2.449 0.553 - 402 1 1 0 0.0028 14 0 0 0 8.77E+06 1.51E+06 - - - 5.3722 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.16369.16369.2 0.189 14-Aug R.ALDIPLVK.N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 867.543 1.38 40200 16369 2 867.543999 434.7788 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3326.1 - 1.84E+06 - - - 1.2046 - 1.461 0.246 - 228.1 1 2 0 0.001 8 0 0 0 1.31E+08 9.49E+07 - - - 2.001 0.9542 230117_WJC_METTL3_WT_vs_EV_F05.16371.16371.2 0.00175 12-Jul Q.AAILHLK[136.11].R "sp|Q68DA7|FMN1_HUMAN,sp|Q8NHP7|EXD1_HUMAN,tr|H0YM30|H0YM30_HUMAN,tr|A0A5F9ZHS8|A0A5F9ZHS8_HUMAN" 4 772.5051 1.73 40202 16371 2 772.505653 387.2598 Formin-1 OS=Homo sapiens OX=9606 GN=FMN1 PE=1 SV=3 8.8 3326.3 - 914795 - - - 0.7689 - 1.527 0.363 - 213.3 1 1 0 0.0006 7 0 0 0 5.88E+07 3.40E+07 - - - 3.0632 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16373.16373.2 0.000639 16-Aug K.GLIDYETFK.E sp|P15924|DESP_HUMAN 1 1084.5441 3.46 40204 16373 2 1084.545502 543.2793 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3326.5 - 650518 - - - 1.3139 - 1.7 0.412 - 169.2 1 2 0 0.0014 9 0 0 0 6.41E+06 1.85E+06 - - - 3.6187 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.16381.16381.2 0.0302 14-Jul K.VTNLLMLK.G "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|B4DI28|B4DI28_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|X6R242|X6R242_HUMAN,tr|A0A6Q8PH43|A0A6Q8PH43_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 18 930.5572 1.19 40211 16381 2 930.55863 466.2859 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.72 3327.5 - 4.98E+06 - - - 1.5109 - 1.476 0.329 - 143.6 1 2 0 0.0014 8 0 0 0 8.76E+08 7.34E+08 - - - 2.6448 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.16384.16384.2 0.00025 12-Jul K.YYTLFGR.S sp|P07814|SYEP_HUMAN 1 918.46 1.17 40214 16384 2 918.461576 460.2373 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.59 3327.8 - 1.17E+06 - - - 1.7671 - 1.544 0.408 - 152 1 2 0 0.0016 7 0 0 0 7.22E+07 6.19E+07 - - - 3.4303 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16385.16385.2 0.00166 18-Aug K.AAPEMVSLLK.R "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN,tr|K7EQ99|K7EQ99_HUMAN" 3 1057.5842 1.25 40215 16385 2 1057.586571 529.7994 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 6.05 3327.8 - 1.03E+06 - - - 2.2731 - 1.661 0.455 - 205.9 1 2 0 0.0024 10 0 0 0 3.85E+07 3.08E+07 - - - 3.8172 0.999 230117_WJC_METTL3_WT_vs_EV_F05.16389.16389.2 0.167 14-Aug K.VIILSLDR.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 927.5753 2.33 40217 16389 2 927.577271 464.7949 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.81 3328.4 - 1.08E+07 - - - 2.1066 - 1.61 0.284 - 267.4 1 2 0 0.002 8 0 0 0 2.00E+08 8.56E+07 - - - 2.5743 0.998 230117_WJC_METTL3_WT_vs_EV_F05.16392.16392.2 1.93E-05 18-Sep K.AAPEMVSLLK[136.11].R "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN,tr|K7EQ99|K7EQ99_HUMAN" 3 1065.5984 1.25 40220 16392 2 1065.603461 533.8065 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 6.05 3328.7 - 1.10E+06 - - - 4.7804 - 1.68 0.456 - 330.9 1 2 0 0.0051 10 0 0 0 3.85E+07 3.08E+07 - - - 3.8555 0.9369 230117_WJC_METTL3_WT_vs_EV_F05.16398.16398.2 0.121 26-Oct F.LLIGGGTAAFAAAR[166.11].S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1297.7382 5.8 40226 16398 2 1297.742423 649.8764 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3329.4 - 113967 - - - 3.2618 - 2.017 0.378 - 272.6 1 1 0 0.0042 14 0 0 0 8.77E+06 1.51E+06 - - - 3.5922 0.9936 230117_WJC_METTL3_WT_vs_EV_F05.16401.16401.2 0.266 16-Jun R.LVLQYAPSA.- "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN" 2 960.528 - 40227 16401 2 960.52929 481.2713 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 5.52 3329.9 - 5.02E+06 - - - 1.3087 - 1.325 0.155 - 86.8 3 2 0 0.0013 9 0 0 0 - - - - - 0.7864 0.9942 230117_WJC_METTL3_WT_vs_EV_F05.16403.16403.2 0.0181 16-Aug K.FGLFTPGSR[166.11].L "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 990.5162 0.54 40229 16403 2 990.519701 496.2654 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 9.75 3330.1 - 675889 - - - 3.4982 - 1.85 0.123 - 191.8 2 2 0 0.0035 9 0 0 0 1.39E+08 2.57E+08 - - - 1.5937 0.9912 230117_WJC_METTL3_WT_vs_EV_F05.16406.16406.2 0.000895 22-Aug R.MPGSVIPPPLVR[166.11].G sp|Q86YP4|P66A_HUMAN 1 1271.7299 3.21 40232 16406 2 1271.737563 636.8722 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.5 3330.5 - 134644 - - - 5.9989 - 1.62 0.35 - 114.5 1 2 0 0.0076 12 0 0 0 7.67E+06 2.39E+06 - - - 2.893 0.9854 230117_WJC_METTL3_WT_vs_EV_F05.16411.16411.2 0.807 12-Jun R.SFDLLVK[136.11].N sp|Q9HB71|CYBP_HUMAN 1 828.4837 2.2 40235 16411 2 828.483943 415.2491 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 5.55 3331.2 - 4.50E+06 - - - 0.3476 - 1.018 0.171 - 119.7 1 2 0 0.0003 7 0 0 0 9.42E+07 4.28E+07 - - - 0.3604 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.16413.16413.2 0.00469 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.14 40237 16413 2 1235.763472 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3331.4 - 1.12E+06 - - - 2.6818 - 1.925 0.293 - 246.3 1 2 0 0.0033 11 0 0 0 2.71E+07 2.38E+07 - - - 2.9758 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16414.16414.2 0.000346 20-Nov K.NALESYAFNMK.S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1286.5965 15.24 40238 16414 2 1286.599667 644.3055 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3331.5 - 1.04E+06 - - - 2.4437 - 2.376 0.392 - 430.8 1 2 0 0.0031 11 0 0 0 1.68E+07 1.10E+06 - - - 4.2765 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.16415.16415.2 2.31 12-Sep K.LPLLLSR.M "sp|P49902|5NTC_HUMAN,sp|O95866|G6B_HUMAN,tr|A0A140T9L8|A0A140T9L8_HUMAN,tr|A0A6Q8PHB5|A0A6Q8PHB5_HUMAN,tr|A0A140T9V1|A0A140T9V1_HUMAN,tr|A0A6Q8PHP0|A0A6Q8PHP0_HUMAN,tr|B7ZLJ5|B7ZLJ5_HUMAN,tr|A0A0G2JJG8|A0A0G2JJG8_HUMAN,tr|F8WDG3|F8WDG3_HUMAN,tr|Q5JUV4|Q5JUV4_HUMAN" 10 810.5327 0.69 40239 16415 2 810.534736 406.2736 Cytosolic purine 5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5C2 PE=1 SV=1 9.75 3331.6 - 1.02E+06 - - - 2.4823 - 1.73 0.098 - 433 1 2 0 0.002 7 0 0 0 1.17E+07 1.69E+07 - - - 1.5009 0.9948 230117_WJC_METTL3_WT_vs_EV_F05.16416.16416.2 0.909 14-Sep K.LLELLPGK[136.11].V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 889.5728 2.31 40240 16416 2 889.574923 445.7937 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3331.7 - 1.18E+06 - - - 2.3809 - 1.305 0.176 - 201.9 1 2 0 0.0021 8 0 0 0 9.93E+07 4.30E+07 - - - 1.1431 1 230117_WJC_METTL3_WT_vs_EV_F05.16417.16417.2 0.00879 16-Oct K.NAIVVLIPK.Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 965.6274 2.1 40241 16417 2 965.630551 483.821 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3331.9 - 904013 - - - 3.3118 - 1.894 0.506 - 334.6 1 2 0 0.0032 9 0 0 0 2.01E+08 9.60E+07 - - - 4.6251 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.16419.16419.2 0.044 16-Jul R.LIPDFPVAR.S sp|Q96S55|WRIP1_HUMAN 1 1026.5862 7.73 40243 16419 2 1026.588501 514.3004 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 5.84 3332.1 - 466744 - - - 2.2258 - 1.343 0.31 - 150.9 1 2 0 0.0023 9 0 0 0 4.62E+07 5.98E+06 - - - 2.1831 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.16420.16420.2 0.114 16-Aug K.NAIVVLIPK[136.11].Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 973.6416 2.1 40244 16420 2 973.643865 487.8281 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3332.2 - 440673 - - - 2.3746 - 1.564 0.351 - 132.5 1 2 0 0.0023 9 0 0 0 2.01E+08 9.60E+07 - - - 2.9267 0.9927 230117_WJC_METTL3_WT_vs_EV_F05.16421.16421.2 0.0719 20-Jul R.LVMELSGEMVR[166.11].K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1272.6445 2.48 40245 16421 2 1272.649542 637.3296 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3332.4 - 158486 - - - 3.9233 - 1.436 0.256 - 108.3 4 2 0 0.005 11 0 0 0 1.27E+07 5.13E+06 - - - 1.6402 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.16423.16423.2 0.0541 20-Jul K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.13 40246 16423 2 1245.771319 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3332.6 - 1.71E+06 - - - 2.3207 - 1.414 0.313 - 120.4 1 2 0 0.0029 11 0 0 0 1.18E+08 1.05E+08 - - - 2.2891 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.16427.16427.2 1.25 14-Aug K.LLELLPGK.V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 881.5586 2.31 40249 16427 2 881.561208 441.7866 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3333 - 3.79E+06 - - - 2.9527 - 1.657 0.212 - 216.6 1 2 0 0.0026 8 0 0 0 9.93E+07 4.30E+07 - - - 2.1291 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.16428.16428.2 0.00153 20-Aug R.LVMELSGEMVR.K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1262.6363 2.48 40250 16428 2 1262.641052 632.3254 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3333.1 - 659338 - - - 3.7802 - 1.534 0.326 - 139.9 1 2 0 0.0048 11 0 0 0 1.27E+07 5.13E+06 - - - 2.6049 0.9939 230117_WJC_METTL3_WT_vs_EV_F05.16432.16432.2 0.019 14-Jul K.SIILEGFK.S sp|O95347|SMC2_HUMAN 1 905.5222 0.2 40254 16432 2 905.526453 453.7684 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 5.72 3333.6 - 302390 - - - 4.6758 - 1.314 0.328 - 120.1 1 2 0 0.0042 8 0 0 0 2.33E+06 1.16E+07 - - - 2.2859 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.16436.16436.2 0.219 12-Aug K.NLFELAR.Q "sp|Q9UN37|VPS4A_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 2 861.4709 4.86 40256 16436 2 861.47266 431.7427 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 6 3334.1 - 984435 - - - 2.0987 - 1.34 0.208 - 266.2 1 2 0 0.0018 7 0 0 0 4.04E+07 8.31E+06 - - - 1.5041 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.16438.16438.2 0.00476 16-Aug R.LTQEVLLLR.E "sp|Q5VU43|MYOME_HUMAN,tr|E9PQG4|E9PQG4_HUMAN,tr|A0A087WX83|A0A087WX83_HUMAN,tr|A0A075B749|A0A075B749_HUMAN" 4 1083.6652 2.2 40258 16438 2 1083.667981 542.8399 Myomegalin OS=Homo sapiens OX=9606 GN=PDE4DIP PE=1 SV=3 6 3334.3 - 378044 - - - 2.5709 - 1.965 0.185 - 191.1 1 2 0 0.0028 9 0 0 0 8.50E+06 3.86E+06 - - - 2.3608 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.16449.16449.2 0.0631 16-Jun R.FLIIDEADR.M sp|Q8N8A6|DDX51_HUMAN 1 1090.5659 1.41 40267 16449 2 1090.569841 546.2902 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 4.03 3335.5 - 1.57E+06 - - - 3.6366 - 1.59 0.366 - 101.1 1 2 0 0.004 9 0 0 0 2.71E+07 1.91E+07 - - - 3.0846 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.16450.16450.2 0.475 20-Jul K.LISSVDPQFLK.L "sp|Q9BVG4|PBDC1_HUMAN,tr|A6NDF3|A6NDF3_HUMAN" 2 1245.6969 6.23 40268 16450 2 1245.699613 623.8557 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 5.84 3335.6 - 1.35E+06 - - - 2.1867 - 1.315 0.238 - 95.2 1 2 0 0.0027 11 0 0 0 2.53E+07 4.06E+06 - - - 1.5388 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16451.16451.2 0.00174 16-Oct R.LLQSLLDTR.C sp|Q13045|FLII_HUMAN 1 1057.6132 1.58 40269 16451 2 1057.615561 529.8139 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3335.7 - 1.23E+06 - - - 2.2712 - 2.06 0.411 - 361.9 1 2 0 0.0024 9 0 0 0 1.83E+07 1.16E+07 - - - 4.1667 0.9942 230117_WJC_METTL3_WT_vs_EV_F05.16454.16454.2 0.462 18-Jul R.LLPQVDSVLK.S "sp|Q9C0B9|ZCHC2_HUMAN,tr|K7EKB8|K7EKB8_HUMAN,tr|K7ESN2|K7ESN2_HUMAN" 3 1110.6649 3.53 40272 16454 2 1110.668048 556.3397 Zinc finger CCHC domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZCCHC2 PE=1 SV=6 5.84 3336.1 - 156764 - - - 2.8695 - 1.306 0.2 - 81.7 1 2 0 0.0032 10 0 0 0 1.41E+06 4.00E+05 - - - 1.2624 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.16460.16460.2 0.168 16-Aug K.VYLGDIPLK[136.11].T "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1024.6048 1.32 40276 16460 2 1024.605197 513.3097 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.81 3336.7 - 1.19E+06 - - - 0.3553 - 1.388 0.219 - 158.7 1 2 0 0.0004 9 0 0 0 3.56E+07 2.70E+07 - - - 1.6069 0.9957 230117_WJC_METTL3_WT_vs_EV_F05.16462.16462.2 0.412 14-Jul K.ALDYYMLR.N sp|Q9Y490|TLN1_HUMAN 1 1043.511 5.04 40278 16462 2 1043.509673 522.7628 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.88 3337 - 683266 - - - -1.2736 - 1.507 0.245 - 152.3 1 2 0 -0.0013 8 0 0 0 6.93E+07 1.37E+07 - - - 2.0871 0.9359 230117_WJC_METTL3_WT_vs_EV_F05.16463.16463.2 0.0483 20-Jul K.LISSVDPQFLK[136.11].L "sp|Q9BVG4|PBDC1_HUMAN,tr|A6NDF3|A6NDF3_HUMAN" 2 1253.7111 6.23 40279 16463 2 1253.705909 627.8628 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 5.84 3337.1 - 440161 - - - -4.1317 - 1.227 0.225 - 117.2 1 2 0 -0.0052 11 0 0 0 2.53E+07 4.06E+06 - - - 1.2546 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.16470.16470.2 0.0159 16-Sep K.FGLFTPGSR.L "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 980.508 0.71 40284 16470 2 980.510786 491.2613 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 9.75 3337.9 - 7.68E+06 - - - 2.8761 - 1.901 0.394 - 309.9 1 2 0 0.0028 9 0 0 0 1.34E+08 1.88E+08 - - - 3.8086 0.8683 230117_WJC_METTL3_WT_vs_EV_F05.16473.16473.2 2.17 16-Aug K.DVEIPLDSK[136.11].P "sp|Q16363|LAMA4_HUMAN,tr|A0A0A0MQS9|A0A0A0MQS9_HUMAN,tr|A0A494C139|A0A494C139_HUMAN,tr|A0A0A0MTC7|A0A0A0MTC7_HUMAN" 4 1022.5375 0 40287 16473 2 1022.538871 512.276 Laminin subunit alpha-4 OS=Homo sapiens OX=9606 GN=LAMA4 PE=1 SV=4 4.03 3338.2 - 2.76E+06 - - - 1.3007 - 1.544 0.198 - 112.7 1 1 0 0.0013 9 0 0 0 1.31E+05 2.42E+08 - - - 1.7597 0.9416 230117_WJC_METTL3_WT_vs_EV_F05.16487.16487.2 1.09 14-Aug R.LIAELLSR[166.11].A "sp|Q02040|AK17A_HUMAN,sp|A6NCM1|IQCAL_HUMAN,tr|X6RAJ1|X6RAJ1_HUMAN" 3 923.5679 1.44 40294 16487 2 923.572837 462.7912 A-kinase anchor protein 17A OS=Homo sapiens OX=9606 GN=AKAP17A PE=1 SV=2 6 3339.9 - 1.15E+06 - - - 5.3055 - 1.346 0.105 - 165.8 1 2 0 0.0049 8 0 0 0 2.13E+07 1.47E+07 - - - 0.7111 0.9909 230117_WJC_METTL3_WT_vs_EV_F05.16494.16494.2 0.00792 14-Sep R.IGVDLIMK.T "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 887.515 0.94 40297 16494 2 887.512627 444.7648 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.84 3340.8 - 1.22E+06 - - - -2.7019 - 1.654 0.228 - 161.7 1 2 0 -0.0024 8 0 0 0 3.38E+07 3.60E+07 - - - 2.2419 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16503.16503.2 0.00568 12-Aug K.LFDFPGR.G sp|Q9P258|RCC2_HUMAN 1 850.4337 1.94 40300 16503 2 850.43511 426.2241 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.84 3341.9 - 2.49E+06 - - - 1.6133 - 1.638 0.427 - 254.1 1 2 0 0.0014 7 0 0 0 1.67E+08 8.58E+07 - - - 3.758 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.16504.16504.2 0.376 14-Aug R.DAFLTLAR.D "sp|Q92793|CBP_HUMAN,sp|Q09472|EP300_HUMAN,tr|A0A669KB12|A0A669KB12_HUMAN" 3 905.4971 2.38 40301 16504 2 905.499188 453.7558 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 5.84 3342 - 1.82E+06 - - - 2.3424 - 1.679 0.185 - 252.3 1 2 0 0.0021 8 0 0 0 3.14E+07 1.32E+07 - - - 1.9696 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16525.16525.2 0.00135 14-Oct R.IPQLLLER[166.11].Y "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 990.6101 0.97 40308 16525 2 990.61048 496.3123 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 6 3344.9 - 2.96E+06 - - - 0.3473 - 1.902 0.389 - 492.7 1 2 0 0.0003 8 0 0 0 1.38E+08 1.42E+08 - - - 3.853 0.9853 230117_WJC_METTL3_WT_vs_EV_F05.16527.16527.2 0.223 14-Aug K.GYGFGLIK.L "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 853.4698 1.32 40309 16527 2 853.46868 427.7422 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 3345.2 - 3.49E+06 - - - -1.3006 - 1.176 0.206 - 177.9 1 2 0 -0.0011 8 0 0 0 7.09E+08 5.37E+08 - - - 1.0511 0.999 230117_WJC_METTL3_WT_vs_EV_F05.16531.16531.2 3.10E-05 22-Nov K.VFGAAPLENVVR.K "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 1270.7034 3.24 40310 16531 2 1270.701935 636.359 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 5.97 3345.7 - 3.70E+06 - - - -1.1301 - 2.05 0.405 - 306.3 1 2 0 -0.0014 12 0 0 0 1.01E+08 3.11E+07 - - - 3.9206 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.16547.16547.2 0.000143 13/24 K.VLIIGGGDGGVLR.E "sp|P19623|SPEE_HUMAN,tr|K7ESL0|K7ESL0_HUMAN" 2 1224.719 17.55 40312 16547 2 1224.717671 613.3668 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.81 3348.2 - 1.93E+06 - - - -1.1023 - 1.986 0.5 - 455.4 1 2 0 -0.0014 13 0 0 0 8.28E+07 4.72E+06 - - - 4.4945 0.878 230117_WJC_METTL3_WT_vs_EV_F05.16550.16550.2 0.56 14-Jul R.VAFTLLEK.V "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 4 919.5379 6.76 40314 16550 2 919.534581 460.7762 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 5.97 3348.6 - 1.20E+06 - - - -3.5757 - 1.276 0.095 - 131.1 1 2 0 -0.0033 8 0 0 0 5.85E+07 8.65E+06 - - - 0.4767 0.949 230117_WJC_METTL3_WT_vs_EV_F05.16569.16569.2 0.16 12-Jun K.ELLIFNK[136.11].Q "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 883.5259 1.1 40318 16569 2 883.525616 442.7702 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.1 3351.4 - 1.77E+06 - - - -0.2694 - 1.189 0.019 - 132.7 1 2 0 -0.0002 7 0 0 0 4.94E+08 4.48E+08 - - - -0.2702 0.9962 230117_WJC_METTL3_WT_vs_EV_F05.16583.16583.2 0.0175 18-Jul K.IFFAGDTIPK[136.11].S "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 5 1115.6106 1.67 40321 16583 2 1115.609755 558.8126 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.84 3353.5 - 804885 - - - -0.7996 - 1.592 0.216 - 71.9 1 2 0 -0.0009 10 0 0 0 6.72E+07 4.01E+07 - - - 1.934 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16585.16585.2 0.0578 14-Sep R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 7813.95 40322 16585 2 1000.560442 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3353.7 - 1.26E+09 - - - 1.1084 - 2.125 0.291 - 262.7 1 2 0 0.0011 8 0 0 0 5.12E+11 6.55E+07 - - - 3.4633 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.16589.16589.2 0.574 18-Sep R.LYLINSPVVR.A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1172.6917 1.45 40323 16589 2 1172.690166 587.3531 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3354.2 - 1.81E+06 - - - -1.3456 - 1.772 0.259 - 350.3 1 2 0 -0.0016 10 0 0 0 2.78E+08 1.92E+08 - - - 2.5504 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.16596.16596.2 0.000402 18-Sep R.LYLINSPVVR[166.11].A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1182.7 1.45 40327 16596 2 1182.698491 592.3573 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3355.2 - 823180 - - - -1.2877 - 1.962 0.258 - 304.1 1 2 0 -0.0015 10 0 0 0 2.78E+08 1.92E+08 - - - 2.8273 1 230117_WJC_METTL3_WT_vs_EV_F05.16598.16598.2 8.90E-07 22-Dec R.GYISPYFINTSK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1388.6976 2.38 40328 16598 2 1388.696481 695.3561 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3355.5 - 1.69E+06 - - - -0.818 - 2.415 0.529 - 530.5 1 2 0 -0.0011 12 0 0 0 4.62E+07 1.94E+07 - - - 5.2677 0.9939 230117_WJC_METTL3_WT_vs_EV_F05.16605.16605.2 1.25 14-Oct K.IPLGLDLK.N "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 867.543 1.58 40330 16605 2 867.544922 434.7788 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.84 3356.4 - 1.26E+06 - - - 2.2685 - 1.7 0.046 - 302.9 1 2 0 0.002 8 0 0 0 1.03E+08 6.49E+07 - - - 0.9805 1 230117_WJC_METTL3_WT_vs_EV_F05.16606.16606.2 0.000358 18-Dec R.VAAAVDLIIK.S "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1011.6328 1.65 40331 16606 2 1011.6254 506.8237 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3356.6 - 1.41E+06 - - - -7.3465 - 2.469 0.444 - 430.9 1 2 0 -0.0074 10 0 0 0 6.75E+07 4.09E+07 - - - 4.8409 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.16621.16621.2 2.46E-05 18-Oct R.GTPLISPLIK.W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1037.6485 1.69 40335 16621 2 1037.646644 519.8315 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3358.6 - 2.72E+06 - - - -1.7713 - 1.66 0.365 - 380.2 1 2 0 -0.0018 10 0 0 0 1.13E+08 6.68E+07 - - - 3.151 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.16622.16622.2 0.0704 16-Sep K.MMLDDIVSR.G "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 6 1078.5151 0.56 40336 16622 2 1078.517356 540.2648 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.21 3358.8 - 642455 - - - 2.0899 - 1.756 0.316 - 249.6 1 2 0 0.0023 9 0 0 0 1.13E+07 2.02E+07 - - - 3.0032 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.16623.16623.2 2.36E-05 18-Sep R.YGLAAAVFTR.D sp|P30837|AL1B1_HUMAN 1 1067.5764 3.24 40337 16623 2 1067.574289 534.7955 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 8.75 3358.9 - 1.53E+06 - - - -1.9586 - 2.094 0.381 - 268.7 1 2 0 -0.0021 10 0 0 0 3.37E+07 1.04E+07 - - - 3.9174 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.16628.16628.2 0.0072 12-Jul K.FTVPMLK[136.11].E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 842.4815 0.86 40340 16628 2 842.479738 422.248 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3359.6 - 699412 - - - -2.1472 - 1.55 0.297 - 174.5 1 2 0 -0.0018 7 0 0 0 2.41E+07 2.81E+07 - - - 2.6227 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.16632.16632.2 0.00114 18-Aug R.GTPLISPLIK[136.11].W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1045.6627 1.69 40342 16632 2 1045.659947 523.8386 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3360 - 1.88E+06 - - - -2.6156 - 1.6 0.443 - 223.8 1 2 0 -0.0027 10 0 0 0 1.13E+08 6.68E+07 - - - 3.6241 0.9715 230117_WJC_METTL3_WT_vs_EV_F05.16633.16633.2 0.396 12-Aug K.FTVPMLK.E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 834.4673 0.85 40343 16633 2 834.465911 418.2409 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3360.1 - 653192 - - - -1.7209 - 1.282 0.125 - 239.2 1 2 0 -0.0014 7 0 0 0 2.55E+07 2.99E+07 - - - 0.7509 0.9888 230117_WJC_METTL3_WT_vs_EV_F05.16634.16634.2 0.621 16-Aug K.GSLLPTSPR.L "tr|H7C179|H7C179_HUMAN,tr|H7C128|H7C128_HUMAN,tr|H7C127|H7C127_HUMAN" 3 926.5185 1.41 40344 16634 2 926.520578 464.2665 Bromodomain-containing protein 8 (Fragment) OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=1 9.75 3360.2 - 1.07E+06 - - - 2.2093 - 1.43 0.06 - 181.8 1 2 0 0.002 9 0 0 0 1.19E+08 8.47E+07 - - - 0.5183 1 230117_WJC_METTL3_WT_vs_EV_F05.16637.16637.2 8.39E-07 22-Nov R.GYISPYFINTSK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1396.7118 2.38 40347 16637 2 1396.710515 699.3632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3360.6 - 488938 - - - -0.9322 - 2.355 0.593 - 455.6 1 2 0 -0.0013 12 0 0 0 4.62E+07 1.94E+07 - - - 5.6742 0.9957 230117_WJC_METTL3_WT_vs_EV_F05.16647.16647.2 0.00465 20-Jul K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.13 40354 16647 2 1235.757127 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3361.9 - 3.19E+06 - - - -2.4527 - 1.676 0.334 - 148.2 1 2 0 -0.003 11 0 0 0 9.10E+07 8.08E+07 - - - 2.904 0.9916 230117_WJC_METTL3_WT_vs_EV_F05.16651.16651.2 0.0414 18-Aug R.TLGGLEMELR.L "sp|Q9Y4L1|HYOU1_HUMAN,tr|A0A087WWI4|A0A087WWI4_HUMAN,tr|K7EQK2|K7EQK2_HUMAN,tr|A0A494C039|A0A494C039_HUMAN,tr|A0A087X054|A0A087X054_HUMAN,tr|E9PJ21|E9PJ21_HUMAN" 6 1117.5801 0.46 40358 16651 2 1117.580132 559.7973 Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1 4.53 3362.4 - 913889 - - - -0.0116 - 1.206 0.178 - 130.5 1 2 0 0 10 0 0 0 4.40E+06 9.61E+06 - - - 0.8785 1 230117_WJC_METTL3_WT_vs_EV_F05.16652.16652.2 0.000135 13/20 R.FGGLVLSPVGK.Q sp|Q9UJK0|TSR3_HUMAN 1 1072.6281 1.39 40359 16652 2 1072.624584 537.3213 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.75 3362.5 - 707047 - - - -3.2602 - 2.455 0.527 - 582.1 1 2 0 -0.0035 11 0 0 0 2.80E+07 2.02E+07 - - - 5.362 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16655.16655.2 0.11 20-Sep K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.13 40361 16655 2 1245.768624 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3362.8 - 1.01E+06 - - - 0.1573 - 1.954 0.424 - 242 1 2 0 0.0002 11 0 0 0 1.18E+08 1.05E+08 - - - 3.9848 1 230117_WJC_METTL3_WT_vs_EV_F05.16658.16658.2 0.000191 20-Nov R.FGGLVLSPVGK[136.11].Q sp|Q9UJK0|TSR3_HUMAN 1 1080.6423 1.45 40363 16658 2 1080.647154 541.3284 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.75 3363.1 - 1.45E+06 - - - 4.5094 - 2.237 0.464 - 375.2 1 2 0 0.0049 11 0 0 0 2.79E+07 1.92E+07 - - - 4.6447 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.16659.16659.2 0.114 12-Jul K.LMIWDTR.S "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 933.4742 1.31 40364 16659 2 933.475058 467.7444 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3363.2 - 3.27E+06 - - - 0.8945 - 1.467 0.316 - 288.2 1 2 0 0.0008 7 0 0 0 1.59E+08 1.21E+08 - - - 2.589 0.9326 230117_WJC_METTL3_WT_vs_EV_F05.16660.16660.2 0.946 12-Jun R.FVAELWK[136.11].D sp|P35580|MYH10_HUMAN 1 899.4996 0.7 40365 16660 2 899.497139 450.7571 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3363.3 - 1.12E+06 - - - -2.7804 - 1.246 0.115 - 95.1 1 2 0 -0.0025 7 0 0 0 4.09E+07 5.81E+07 - - - 0.5865 0.9948 230117_WJC_METTL3_WT_vs_EV_F05.16661.16661.2 0.0334 16-Aug R.GLFTGLTPR.L "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 960.5393 1.21 40366 16661 2 960.537922 481.2769 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3363.4 - 506352 - - - -1.3992 - 1.374 0.274 - 164.8 1 2 0 -0.0013 9 0 0 0 3.24E+07 2.67E+07 - - - 1.9835 0.998 230117_WJC_METTL3_WT_vs_EV_F05.16668.16668.2 0.321 14-Aug R.QVFLATWK.D "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 991.5491 0 40371 16668 2 991.5504 496.7818 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.75 3364.3 - 542769 - - - 1.3091 - 1.235 0.276 - 176.2 1 2 0 0.0013 8 0 0 0 8.33E+06 1.14E+10 - - - 1.7157 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.16674.16674.2 0.00252 16-Dec K.LLC[160.03]GLLAER[166.11].L sp|P14174|MIF_HUMAN 1 1053.588 0.9 40375 16674 2 1053.586789 527.8013 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3365.1 - 4.41E+06 - - - -1.1693 - 2.165 0.335 - 427.6 1 2 0 -0.0012 9 0 0 0 6.51E+08 7.20E+08 - - - 3.7496 0.995 230117_WJC_METTL3_WT_vs_EV_F05.16676.16676.2 0.794 12-Jul R.ILLQYLK.Q "sp|Q9P0U3|SENP1_HUMAN,sp|Q9NVH2|INT7_HUMAN" 2 889.5637 4.08 40377 16676 2 889.564866 445.7891 Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2 8.59 3365.3 - 2.81E+06 - - - 1.322 - 1.342 0.135 - 146.2 1 2 0 0.0012 7 0 0 0 1.36E+07 3.33E+06 - - - 0.9698 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.16677.16677.2 0.0355 18-Nov K.APGLGLVLER.V "sp|Q9Y606|TRUA_HUMAN,tr|G8JLB3|G8JLB3_HUMAN,tr|F5H1S9|F5H1S9_HUMAN" 3 1023.6077 1.73 40378 16677 2 1023.610193 512.8111 tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3 6.05 3365.4 - 2.18E+06 - - - 2.455 - 1.873 0.323 - 231 1 2 0 0.0025 10 0 0 0 1.09E+07 6.31E+06 - - - 3.1775 0.9915 230117_WJC_METTL3_WT_vs_EV_F05.16681.16681.2 0.0642 12-Jun R.GFELTFK[136.11].T "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 848.4524 1.51 40382 16681 2 848.456038 425.2335 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3365.9 - 800331 - - - 4.3408 - 1.202 0.289 - 129.9 1 2 0 0.0037 7 0 0 0 4.45E+07 2.95E+07 - - - 1.7574 0.9852 230117_WJC_METTL3_WT_vs_EV_F05.16685.16685.2 0.328 16-Jun R.YVANLFPYK[136.11].G "sp|Q15181|IPYR_HUMAN,sp|Q9H2U2|IPYR2_HUMAN,tr|D6RGV9|D6RGV9_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN,tr|D6RGI1|D6RGI1_HUMAN,tr|H0YAK2|H0YAK2_HUMAN" 7 1121.6001 2.67 40386 16685 2 1121.603396 561.8073 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 8.5 3366.4 - 536372 - - - 2.9547 - 0.937 0.237 - 104.5 1 2 0 0.0033 9 0 0 0 5.98E+07 2.24E+07 - - - 0.6022 0.998 230117_WJC_METTL3_WT_vs_EV_F05.16688.16688.2 0.0246 22-Jul R.NSLGGDVLFVGK.H sp|Q9H0D6|XRN2_HUMAN 1 1204.6452 2.89 40389 16688 2 1204.645326 603.3299 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3366.8 - 410808 - - - 0.1146 - 1.375 0.291 - 94.5 1 2 0 0.0001 12 0 0 0 3.11E+06 1.07E+06 - - - 2.0282 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.16692.16692.2 0.00246 16-Oct K.LLC[160.03]GLLAER.L sp|P14174|MIF_HUMAN 1 1043.5798 0.87 40392 16692 2 1043.580017 522.7972 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3367.1 - 1.68E+06 - - - 0.2549 - 2.017 0.331 - 280.8 1 2 0 0.0003 9 0 0 0 6.10E+08 6.99E+08 - - - 3.5155 0.9906 230117_WJC_METTL3_WT_vs_EV_F05.16693.16693.2 1.53 12-May R.FVAELWK.D sp|P35580|MYH10_HUMAN 1 891.4854 0.69 40393 16693 2 891.486365 446.75 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3367.2 - 1.21E+06 - - - 1.0376 - 1.113 0.156 - 81.7 1 2 0 0.0009 7 0 0 0 4.11E+07 5.96E+07 - - - 0.5321 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.16695.16695.2 0.0717 16-Aug R.GLFTGLTPR[166.11].L "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 970.5475 1.24 40395 16695 2 970.547407 486.281 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3367.4 - 642641 - - - -0.1329 - 1.723 0.241 - 186.2 1 2 0 -0.0001 9 0 0 0 3.23E+07 2.61E+07 - - - 2.395 1 230117_WJC_METTL3_WT_vs_EV_F05.16697.16697.2 5.36E-05 18-Nov K.VYVIGSFVDK[136.11].S sp|Q7L0Y3|TM10C_HUMAN 1 1133.6212 0.76 40397 16697 2 1133.622342 567.8179 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3367.7 - 445875 - - - 0.9977 - 2.135 0.502 - 358.6 1 2 0 0.0011 10 0 0 0 1.85E+07 2.44E+07 - - - 4.8655 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.16704.16704.2 0.385 18-Nov K.VYVIGSFVDK.S sp|Q7L0Y3|TM10C_HUMAN 1 1125.607 0.76 40402 16704 2 1125.610796 563.8108 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3368.5 - 461423 - - - 3.3626 - 2.502 0.391 - 393.6 1 2 0 0.0038 10 0 0 0 1.85E+07 2.44E+07 - - - 4.4876 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16709.16709.2 0.000568 22-Aug R.VLIGNVQPGILR.F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1277.782 3 40407 16709 2 1277.784096 639.8983 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3369.2 - 42322.5 - - - 1.6748 - 1.786 0.398 - 264.5 1 2 0 0.0021 12 0 0 0 5.76E+06 1.92E+06 - - - 3.506 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.16711.16711.2 0.00327 12-Jul K.LMIWDTR[166.11].S "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 943.4825 1.85 40408 16711 2 943.483904 472.7485 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3369.4 - 5.02E+06 - - - 1.4955 - 1.464 0.399 - 289 1 2 0 0.0014 7 0 0 0 1.62E+08 8.79E+07 - - - 3.1953 0.9676 230117_WJC_METTL3_WT_vs_EV_F05.16714.16714.2 0.981 12-Aug K.LDDLFLK.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 862.48 1.02 40410 16714 2 862.47787 432.2473 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3369.7 - 1.38E+06 - - - -2.4928 - 1.603 0.065 - 217 1 2 0 -0.0022 7 0 0 0 9.31E+07 9.13E+07 - - - 1.0156 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.16716.16716.2 1.7 12-Aug R.LTLLQLK.G sp|Q8NHP8|PLBL2_HUMAN 1 827.548 1.2 40412 16716 2 827.54986 414.7813 Putative phospholipase B-like 2 OS=Homo sapiens OX=9606 GN=PLBD2 PE=1 SV=2 8.75 3369.9 - 476264 - - - 2.1993 - 1.677 0.135 - 156.9 1 2 0 0.0018 7 0 0 0 1.54E+07 1.29E+07 - - - 1.6757 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.16717.16717.2 0.00854 16-Jun K.FLGELYNYR[166.11].M sp|Q9HAU5|RENT2_HUMAN 1 1183.5901 0.79 40413 16717 2 1183.593877 592.8023 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 6 3370 - 435848 - - - 3.1666 - 1.357 0.303 - 87.3 1 2 0 0.0037 9 0 0 0 5.15E+06 6.52E+06 - - - 2.161 0.9722 230117_WJC_METTL3_WT_vs_EV_F05.16719.16719.2 0.845 22-Apr R.MPGSVIPPPLVR.G sp|Q86YP4|P66A_HUMAN 1 1261.7217 9.04 40415 16719 2 1261.725222 631.8681 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.5 3370.3 - 105268 - - - 2.82 - 1.179 0.137 - 43.4 7 2 0 0.0036 12 0 0 0 1.78E+06 1.97E+05 - - - 0.1075 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.16723.16723.2 0.396 14-Jun R.ILELDQFK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1012.5684 1.27 40416 16723 2 1012.569521 507.2915 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3370.9 - 4.81E+06 - - - 1.0607 - 1.392 0.186 - 82.1 1 2 0 0.0011 8 0 0 0 2.71E+08 2.14E+08 - - - 1.412 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.16724.16724.2 0.0569 20-Jul K.FLVGPDGVPLR[166.11].R "sp|P07203|GPX1_HUMAN,tr|A0A2R8Y6B6|A0A2R8Y6B6_HUMAN" 2 1178.6687 2.46 40417 16724 2 1178.671861 590.3416 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 5.84 3371 - 191602 - - - 2.67 - 1.425 0.289 - 105.5 1 2 0 0.0031 11 0 0 0 5.89E+06 2.40E+06 - - - 2.1327 0.992 230117_WJC_METTL3_WT_vs_EV_F05.16726.16726.2 0.179 18-Aug K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 2.38 40419 16726 2 1146.633431 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3371.3 - 278047 - - - 4.3222 - 1.453 0.232 - 126.5 1 2 0 0.005 10 0 0 0 2.92E+06 1.23E+06 - - - 1.7959 0.8492 230117_WJC_METTL3_WT_vs_EV_F05.16735.16735.2 1.04 16-Jul K.YFLGQSVLR.S "sp|Q9Y255|PRLD1_HUMAN,tr|D6REW1|D6REW1_HUMAN,tr|D6RC47|D6RC47_HUMAN" 3 1081.592 1.58 40426 16735 2 1081.587247 541.8033 "PRELI domain-containing protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=PRELID1 PE=1 SV=1" 8.75 3372.4 - 345383 - - - -4.4222 - 1.155 0.165 - 105.8 1 2 0 -0.0048 9 0 0 0 9.16E+06 5.79E+06 - - - 0.6751 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.16738.16738.2 0.00652 22-Aug R.VLIGNVQPGILR[166.11].F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1287.7902 3 40429 16738 2 1287.796601 644.9024 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3372.8 - 144071 - - - 4.9503 - 1.626 0.369 - 155.2 1 2 0 0.0064 12 0 0 0 5.76E+06 1.92E+06 - - - 3.0435 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.16743.16743.2 0.00387 14-Aug R.VWDISGLR[166.11].K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 954.5162 3.25 40432 16743 2 954.516252 478.2654 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3373.5 - 654684 - - - 0.0168 - 1.773 0.138 - 200.5 1 2 0 0 8 0 0 0 6.16E+07 1.89E+07 - - - 1.7874 1 230117_WJC_METTL3_WT_vs_EV_F05.16746.16746.2 0.00134 20-Nov R.ALDEGDIALLK[136.11].T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1164.6482 2.76 40435 16746 2 1164.650124 583.3314 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 3373.8 - 390215 - - - 1.6915 - 2.362 0.469 - 251.9 1 2 0 0.002 11 0 0 0 1.23E+07 4.47E+06 - - - 4.8296 0.999 230117_WJC_METTL3_WT_vs_EV_F05.16756.16756.2 0.302 14-Aug R.ILELDQFK.G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1004.5542 1.05 40443 16756 2 1004.557378 503.2844 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3375.1 - 9.29E+06 - - - 3.1168 - 1.785 0.325 - 156.9 1 2 0 0.0031 8 0 0 0 2.22E+08 2.12E+08 - - - 3.188 0.9887 230117_WJC_METTL3_WT_vs_EV_F05.16757.16757.2 0.0296 14-Jul R.VWDISGLR.K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 944.508 3.27 40444 16757 2 944.511074 473.2613 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3375.1 - 2.78E+06 - - - 3.2906 - 1.669 0.049 - 230.2 1 2 0 0.0031 8 0 0 0 6.19E+07 1.89E+07 - - - 0.9468 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.16758.16758.2 0.0399 13/18 R.ALEAELAALR[166.11].Q sp|Q16352|AINX_HUMAN 1 1065.6058 8.04 40445 16758 2 1065.609814 533.8102 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.53 3375.2 - 1.00E+06 - - - 3.7866 - 2.041 0.283 - 615.6 1 2 0 0.004 10 0 0 0 1.52E+08 1.89E+07 - - - 3.1214 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.16760.16760.2 0.000623 18-Oct R.FGVITEVDIK[136.11].R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1127.6318 2.14 40447 16760 2 1127.635715 564.8232 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 4.37 3375.5 - 569701 - - - 3.4932 - 2.087 0.418 - 312.2 1 2 0 0.0039 10 0 0 0 2.15E+07 1.01E+07 - - - 4.1808 0.9956 230117_WJC_METTL3_WT_vs_EV_F05.16766.16766.2 2.32 12-Aug K.LDDLFLK[136.11].R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 870.4942 1.05 40451 16766 2 870.497232 436.2544 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3376.2 - 6.52E+06 - - - 3.4601 - 1.936 0.091 - 179.6 1 2 0 0.003 7 0 0 0 9.32E+07 8.87E+07 - - - 1.8054 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.16768.16768.3 2.78E-06 18/64 K.MLQAPESVLAEHYQDLR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 2008.9916 0.93 40453 16768 3 2008.998836 670.6711 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3376.5 - 417213 - - - 3.6113 - 3.078 0.496 - 248.3 1 2 0 0.0073 17 0 0 0 3.95E+06 4.23E+06 - - - 6.9082 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.16769.16769.3 1.05E-06 20/64 K.MLQAPESVLAEHYQDLR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1998.9833 0.93 40454 16769 3 1998.990055 667.335 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3376.6 - 358374 - - - 3.3737 - 3.171 0.539 - 367.5 1 2 0 0.0067 17 0 0 0 3.95E+06 4.23E+06 - - - 7.4629 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.16770.16770.2 0.164 20-Jul R.ALAAQLPVLPR.S "sp|Q96GK7|FAH2A_HUMAN,tr|C9JGM0|C9JGM0_HUMAN" 2 1147.7077 3.49 40455 16770 2 1147.712292 574.8611 Fumarylacetoacetate hydrolase domain-containing protein 2A OS=Homo sapiens OX=9606 GN=FAHD2A PE=1 SV=1 9.79 3376.8 - 291434 - - - 3.9766 - 1.712 0.258 - 113.4 2 2 0 0.0046 11 0 0 0 8.70E+06 2.49E+06 - - - 2.2652 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.16772.16772.2 0.105 20-Sep K.LLAAFPGVTPR.V "sp|Q9Y2I1|NISCH_HUMAN,tr|C9J715|C9J715_HUMAN" 2 1140.6655 2.96 40457 16772 2 1140.666105 571.34 Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3 9.75 3377 - 220422 - - - 0.505 - 1.706 0.27 - 188.5 1 2 0 0.0006 11 0 0 0 9.17E+06 3.10E+06 - - - 2.48 0.9949 230117_WJC_METTL3_WT_vs_EV_F05.16773.16773.2 0.000168 18-Sep K.IVAFENAFER.L sp|O60763|USO1_HUMAN 1 1194.6033 1.09 40458 16773 2 1194.609895 598.3089 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 3377.1 - 215981 - - - 5.5014 - 1.728 0.352 - 191.4 1 2 0 0.0066 10 0 0 0 5.25E+06 4.80E+06 - - - 3.1656 0.9909 230117_WJC_METTL3_WT_vs_EV_F05.16778.16778.2 0.326 14-Jul R.LGISSLIR.E sp|P35573|GDE_HUMAN 1 857.5335 0.97 40461 16778 2 857.535409 429.774 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3377.8 - 3.43E+06 - - - 2.2821 - 1.258 0.13 - 139.7 1 2 0 0.002 8 0 0 0 3.83E+07 3.94E+07 - - - 0.6928 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.16779.16779.2 0.00112 14-Aug K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 0.75 40462 16779 2 988.573747 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3377.9 - 1.16E+06 - - - 3.2178 - 1.753 0.334 - 292.5 1 2 0 0.0032 8 0 0 0 3.23E+09 4.31E+09 - - - 3.1999 0.9707 230117_WJC_METTL3_WT_vs_EV_F05.16781.16781.2 0.0714 12-May K.FIDPFC[160.03]K.L sp|Q14684|RRP1B_HUMAN 1 925.4368 2.74 40464 16781 2 925.440776 463.7257 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.83 3378.1 - 1.08E+06 - - - 4.3234 - 1 0.231 - 76.2 1 2 0 0.004 7 0 0 0 2.71E+07 9.87E+06 - - - 0.7459 0.9947 230117_WJC_METTL3_WT_vs_EV_F05.16783.16783.2 0.0194 14-Jul K.LEPDILLR.A "sp|Q01433|AMPD2_HUMAN,tr|A0A7P0TB79|A0A7P0TB79_HUMAN,tr|A0A590UK85|A0A590UK85_HUMAN,tr|A0A5F9UK94|A0A5F9UK94_HUMAN,tr|E9PJF6|E9PJF6_HUMAN,tr|A0A590UJX5|A0A590UJX5_HUMAN,tr|H0Y360|H0Y360_HUMAN,tr|A0A7P0Z4H6|A0A7P0Z4H6_HUMAN,tr|E9PIJ1|E9PIJ1_HUMAN,tr|H0YF16|H0YF16_HUMAN,tr|A0A804CCZ3|A0A804CCZ3_HUMAN" 11 967.5702 2.41 40466 16783 2 967.574011 484.7924 AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2 4.37 3378.4 - 411602 - - - 3.9057 - 1.588 0.201 - 134.6 1 2 0 0.0038 8 0 0 0 1.01E+07 4.18E+06 - - - 1.9192 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.16785.16785.2 0.0048 20-Aug R.LYPEGLAQLAR.A "sp|P61421|VA0D1_HUMAN,tr|J3QL14|J3QL14_HUMAN,tr|F5GYQ1|F5GYQ1_HUMAN,tr|R4GN72|R4GN72_HUMAN" 4 1229.6768 1.46 40468 16785 2 1229.67986 615.8457 V-type proton ATPase subunit d 1 OS=Homo sapiens OX=9606 GN=ATP6V0D1 PE=1 SV=1 6 3378.6 - 160601 - - - 2.4706 - 1.491 0.194 - 167.8 1 2 0 0.003 11 0 0 0 1.21E+07 8.27E+06 - - - 1.5535 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.16788.16788.2 0.0502 14-Sep K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 0.75 40469 16788 2 998.583075 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3379 - 8.17E+06 - - - 4.245 - 1.714 0.309 - 363 1 2 0 0.0042 8 0 0 0 3.19E+09 4.26E+09 - - - 2.947 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.16791.16791.2 6.29E-05 16-Sep R.YVANLFPYK.G "sp|Q15181|IPYR_HUMAN,sp|Q9H2U2|IPYR2_HUMAN,tr|D6RGV9|D6RGV9_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN,tr|D6RGI1|D6RGI1_HUMAN,tr|H0YAK2|H0YAK2_HUMAN" 7 1113.5859 2.67 40472 16791 2 1113.590632 557.8002 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 8.5 3379.3 - 1.75E+06 - - - 4.2655 - 1.509 0.435 - 239.7 1 2 0 0.0048 9 0 0 0 5.99E+07 2.24E+07 - - - 3.4428 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.16794.16794.2 0.000143 16-Oct R.ATLNAFLYR[166.11].T "sp|Q5T2N8|ATD3C_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 3 1077.5847 1.26 40475 16794 2 1077.589254 539.7996 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 8.79 3379.7 - 476114 - - - 4.2725 - 2.113 0.404 - 305.5 1 2 0 0.0046 9 0 0 0 4.51E+07 3.58E+07 - - - 4.1878 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.16801.16801.2 0.000763 16-Sep R.EPGEFALLR[166.11].S sp|O43505|B4GA1_HUMAN 1 1040.553 2.48 40480 16801 2 1040.55444 521.2838 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 4.53 3380.6 - 1.73E+06 - - - 1.3695 - 1.741 0.36 - 365 1 2 0 0.0014 9 0 0 0 1.35E+08 5.45E+07 - - - 3.3036 0.9946 230117_WJC_METTL3_WT_vs_EV_F05.16803.16803.2 1.24 14-Jun R.DILLQGLK[136.11].A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 906.563 0.8 40482 16803 2 906.564439 454.2888 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3380.7 - 1.57E+06 - - - 1.6226 - 1.28 0.155 - 94 1 2 0 0.0015 8 0 0 0 1.62E+07 2.01E+07 - - - 0.9299 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.16804.16804.2 0.0527 16-Jul K.IDPEAFITR.H sp|Q92616|GCN1_HUMAN 1 1060.5553 1.17 40483 16804 2 1060.556334 531.2849 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3380.8 - 1.47E+06 - - - 0.9655 - 1.492 0.216 - 139.3 1 2 0 0.001 9 0 0 0 2.67E+07 2.28E+07 - - - 1.7936 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.16805.16805.2 0.329 14-Aug R.DILLQGLK.A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 898.5488 0.81 40484 16805 2 898.550722 450.2817 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3380.8 - 1.37E+06 - - - 2.1746 - 1.448 0.248 - 196.1 1 2 0 0.002 8 0 0 0 1.63E+07 2.01E+07 - - - 1.9886 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.16809.16809.2 0.0013 18-Jul R.VIAIDIDPVK[136.11].L sp|Q96RS0|TGS1_HUMAN 1 1089.6525 1.97 40488 16809 2 1089.655066 545.8335 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 4.21 3381.1 - 692906 - - - 2.3448 - 1.518 0.227 - 109.6 1 2 0 0.0026 10 0 0 0 2.14E+07 1.09E+07 - - - 1.8819 1 230117_WJC_METTL3_WT_vs_EV_F05.16812.16812.2 5.76E-05 20-Nov R.FDLALAATEAR.Q sp|Q6PD62|CTR9_HUMAN 1 1176.6139 1.9 40491 16812 2 1176.61566 589.3142 RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1 4.37 3381.5 - 186320 - - - 1.506 - 2.318 0.494 - 338.6 1 2 0 0.0018 11 0 0 0 6.60E+06 3.48E+06 - - - 4.9634 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.16817.16817.2 0.061 14-Jun R.LELSVLYK.E "sp|Q96FW1|OTUB1_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 5 963.5641 2.66 40494 16817 2 963.564974 482.7893 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 6 3382.1 - 470451 - - - 0.9237 - 1.423 0.215 - 71.6 1 2 0 0.0009 8 0 0 0 1.71E+07 6.42E+06 - - - 1.6926 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.16825.16825.2 0.000488 18-Sep R.LLLNNDNLLR.E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1196.6877 1.54 40499 16825 2 1196.692774 599.3511 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3383 - 832880 - - - 4.2225 - 1.879 0.399 - 221.3 1 2 0 0.0051 10 0 0 0 2.59E+08 1.68E+08 - - - 3.747 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16826.16826.2 0.0138 18-Sep K.IEDMAVSLIR.E sp|Q15776|ZKSC8_HUMAN 1 1145.6114 1.29 40500 16826 2 1145.613065 573.813 Zinc finger protein with KRAB and SCAN domains 8 OS=Homo sapiens OX=9606 GN=ZKSCAN8 PE=1 SV=2 4.37 3383.1 - 628215 - - - 1.4141 - 1.937 0.356 - 214.9 1 2 0 0.0016 10 0 0 0 4.21E+06 3.26E+06 - - - 3.5154 0.9734 230117_WJC_METTL3_WT_vs_EV_F05.16827.16827.2 0.047 12-May K.IFNFYPR.K "sp|O14531|DPYL4_HUMAN,tr|Q5T0Q6|Q5T0Q6_HUMAN" 2 955.4916 2.28 40501 16827 2 955.488517 478.7531 Dihydropyrimidinase-related protein 4 OS=Homo sapiens OX=9606 GN=DPYSL4 PE=1 SV=2 8.75 3383.2 - 734330 - - - -3.2141 - 1.208 0.257 - 65.3 1 2 0 -0.0031 7 0 0 0 4.20E+06 1.84E+06 - - - 1.537 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.16834.16834.2 0.00522 18-Sep R.LLLNNDNLLR[166.11].E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1206.696 1.54 40506 16834 2 1206.69614 604.3553 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3384.1 - 1.86E+06 - - - 0.1235 - 2.111 0.269 - 238.7 1 2 0 0.0001 10 0 0 0 2.59E+08 1.68E+08 - - - 3.1133 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.16835.16835.2 0.477 12-Sep R.IQLIFER.A "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 917.5335 0.84 40507 16835 2 917.534103 459.774 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 3384.2 - 1.90E+06 - - - 0.7095 - 1.735 0.118 - 246.9 1 2 0 0.0007 7 0 0 0 3.37E+07 4.02E+07 - - - 1.6582 0.9661 230117_WJC_METTL3_WT_vs_EV_F05.16837.16837.2 2.67 12-May K.VLLPFTR.A sp|Q8TEM1|PO210_HUMAN 1 844.5171 2.18 40509 16837 2 844.517815 423.2658 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 9.72 3384.4 - 966909 - - - 0.8774 - 1.167 0.021 - 91.8 1 2 0 0.0007 7 0 0 0 4.29E+07 1.97E+07 - - - -0.3148 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.16839.16839.2 0.00119 18-Sep K.AVFVPDIYSR.T sp|O94874|UFL1_HUMAN 1 1165.6132 1.53 40511 16839 2 1165.611992 583.8139 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.88 3384.7 - 475727 - - - -1.0012 - 1.931 0.438 - 255.4 1 2 0 -0.0012 10 0 0 0 7.97E+06 5.21E+06 - - - 4.1125 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.16845.16845.2 0.476 12-Aug R.LLQLWEK[136.11].N "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 936.5524 1.35 40515 16845 2 936.55343 469.2835 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 6 3385.5 - 1.61E+06 - - - 1.0966 - 1.68 0.254 - 178.3 1 2 0 0.001 7 0 0 0 5.07E+07 3.75E+07 - - - 2.5605 0.9913 230117_WJC_METTL3_WT_vs_EV_F05.16846.16846.2 0.632 14-Jun K.YVVGLIIK.T "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 903.5793 1.42 40516 16846 2 903.579476 452.7969 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3385.6 - 1.16E+06 - - - 0.1505 - 1.222 0.155 - 102.9 1 2 0 0.0001 8 0 0 0 2.50E+07 1.76E+07 - - - 0.7905 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.16848.16848.2 0.00869 12-Aug K.TDFGIFR.M "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 10 854.4287 1.95 40518 16848 2 854.428652 428.2216 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.5 3385.8 - 735863 - - - -0.0012 - 1.37 0.35 - 274.4 1 2 0 0 7 0 0 0 1.43E+07 7.31E+06 - - - 2.6236 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.16849.16849.2 0.0262 22-Sep -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 1.47 40519 16849 2 1306.770043 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3386 - 622880 - - - 1.3491 - 1.644 0.204 - 148 1 2 0 0.0018 12 0 0 0 1.13E+07 7.69E+06 - - - 1.8552 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.16850.16850.2 0.00431 14-Jun R.LMGDYLLR.G "sp|O60232|ZNRD2_HUMAN,tr|H0YEK1|H0YEK1_HUMAN,tr|E9PK41|E9PK41_HUMAN,tr|H0YEB6|H0YEB6_HUMAN" 4 979.5161 4.06 40520 16850 2 979.51752 490.7653 Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1 5.84 3386.1 - 565184 - - - 1.4619 - 1.355 0.343 - 84.2 1 2 0 0.0014 8 0 0 0 1.98E+07 4.89E+06 - - - 2.4902 0.9604 230117_WJC_METTL3_WT_vs_EV_F05.16851.16851.2 3.34 14-Jul R.LELSVLYK[136.11].E "sp|Q96FW1|OTUB1_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 5 971.5783 2.55 40521 16851 2 971.57836 486.7964 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 6 3386.1 - 475408 - - - 0.0782 - 1.241 0.011 - 106.2 1 2 0 0.0001 8 0 0 0 1.63E+07 6.42E+06 - - - -0.2266 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.16859.16859.2 0.0749 22-Sep -.MVPPVQVSPLIK[136.11].L sp|P56385|ATP5I_HUMAN 1 1314.7825 1.43 40527 16859 2 1314.783486 658.3985 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3387.2 - 384742 - - - 0.7651 - 1.675 0.264 - 150.9 1 2 0 0.001 12 0 0 0 1.32E+07 9.18E+06 - - - 2.3478 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16866.16866.2 0.0105 16-Aug K.LFSELPLAK.K "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1016.5906 1.26 40532 16866 2 1016.591714 509.3026 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 6 3388 - 4.47E+06 - - - 1.0634 - 1.602 0.42 - 200.8 1 2 0 0.0011 9 0 0 0 1.13E+08 9.03E+07 - - - 3.5061 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.16867.16867.2 0.148 18-Jul R.LGLSTLGELK.Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1029.607 2.57 40533 16867 2 1029.60759 515.8108 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3388 - 3.06E+06 - - - 0.5624 - 1.533 0.177 - 94 2 2 0 0.0006 10 0 0 0 2.75E+08 1.07E+08 - - - 1.4062 1 230117_WJC_METTL3_WT_vs_EV_F05.16869.16869.2 2.38E-07 24-Sep R.ILGVGPDDPDLVR.A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1364.73 2.47 40535 16869 2 1364.7293 683.3723 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3388.2 - 648137 - - - -0.4983 - 2.197 0.56 - 252.1 1 2 0 -0.0007 13 0 0 0 4.24E+06 1.71E+06 - - - 5.197 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.16871.16871.2 0.000119 24-Aug R.ILGVGPDDPDLVR[166.11].A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1374.7383 2.47 40537 16871 2 1374.73955 688.3764 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3388.4 - 432276 - - - 0.9456 - 1.752 0.475 - 199.6 1 2 0 0.0013 13 0 0 0 4.24E+06 1.71E+06 - - - 3.9881 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.16874.16874.2 0.0011 18-Nov R.LGLSTLGELK.Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1029.607 2.57 40538 16874 2 1029.60803 515.8108 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3388.8 - 2.45E+06 - - - 0.9897 - 2.292 0.359 - 273 1 2 0 0.001 10 0 0 0 2.75E+08 1.07E+08 - - - 4.0074 0.9969 230117_WJC_METTL3_WT_vs_EV_F05.16877.16877.2 0.0573 14-Sep K.MFAEIMMK[136.11].L "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1007.4734 0.86 40541 16877 2 1007.478508 504.744 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 5.75 3389 - 1.21E+06 - - - 5.1029 - 1.901 0.34 - 280 1 2 0 0.0051 8 0 0 0 1.11E+07 1.29E+07 - - - 3.488 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16878.16878.2 0.00315 16-Aug R.ELLTEFGYK.G sp|P49411|EFTU_HUMAN 1 1098.5597 2.69 40542 16878 2 1098.561667 550.2871 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.53 3389.1 - 1.00E+06 - - - 1.7659 - 1.531 0.461 - 214.8 1 2 0 0.0019 9 0 0 0 3.63E+07 1.35E+07 - - - 3.6775 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.16882.16882.2 0.16 18-Jun K.AVFVPDIYSR[166.11].T sp|O94874|UFL1_HUMAN 1 1175.6214 1.52 40546 16882 2 1175.620955 588.818 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.88 3389.6 - 336161 - - - -0.4032 - 1.414 0.281 - 101.6 1 2 0 -0.0005 10 0 0 0 7.91E+06 5.21E+06 - - - 2.0833 0.9855 230117_WJC_METTL3_WT_vs_EV_F05.16883.16883.2 0.547 12-Jul R.IQLFLAR.L "sp|Q96FV9|THOC1_HUMAN,tr|A0A087WWS1|A0A087WWS1_HUMAN,tr|A0A087WY84|A0A087WY84_HUMAN,tr|J3KT14|J3KT14_HUMAN" 4 859.528 0.37 40547 16883 2 859.528362 430.7713 THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1 9.75 3389.7 - 314663 - - - 0.4526 - 1.377 0.056 - 118.6 2 2 0 0.0004 7 0 0 0 6.05E+06 1.62E+07 - - - 0.3337 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.16884.16884.2 0.000104 18-Aug R.LLYEALVDC[160.03]K[136.11].K "sp|Q7L2H7|EIF3M_HUMAN,tr|J3KNJ2|J3KNJ2_HUMAN,tr|E9PRY0|E9PRY0_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 4 1230.641 1.03 40548 16884 2 1230.636852 616.3278 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 4.37 3389.9 - 265428 - - - -3.3389 - 1.857 0.431 - 167 1 2 0 -0.0041 10 0 0 0 3.58E+06 3.47E+06 - - - 3.9508 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.16889.16889.2 0.00114 18-Sep R.LGLSTLGELK[136.11].Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1037.6212 2.57 40551 16889 2 1037.622584 519.8179 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3390.6 - 767546 - - - 1.3232 - 2.124 0.402 - 150.5 1 2 0 0.0014 10 0 0 0 2.75E+08 1.07E+08 - - - 4.1124 1 230117_WJC_METTL3_WT_vs_EV_F05.16892.16892.2 2.69E-06 16-Sep R.ELLTEFGYK[136.11].G sp|P49411|EFTU_HUMAN 1 1106.5739 2.64 40554 16892 2 1106.577785 554.2942 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.53 3390.8 - 511862 - - - 3.4864 - 1.934 0.508 - 255.8 1 2 0 0.0039 9 0 0 0 3.63E+07 1.38E+07 - - - 4.7001 1 230117_WJC_METTL3_WT_vs_EV_F05.16896.16896.2 4.60E-06 22-Dec K.VLQGDLVMNVYR.D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1405.7388 7.88 40558 16896 2 1405.741326 703.8767 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3391.2 - 0 - - - 1.8175 - 2.365 0.505 - 537.9 1 2 0 0.0026 12 0 0 0 2.60E+06 3.30E+05 - - - 5.035 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.16901.16901.2 0.0604 14-Jul K.AGPIWDLR[166.11].L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 936.5057 0.96 40561 16901 2 936.507089 469.2601 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3391.9 - 3.49E+06 - - - 1.5141 - 1.393 0.309 - 222.3 1 2 0 0.0014 8 0 0 0 3.39E+08 3.53E+08 - - - 2.3225 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.16902.16902.2 0.00525 14-Aug K.AGPIWDLR.L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 926.4974 0.96 40562 16902 2 926.498599 464.256 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3391.9 - 2.48E+06 - - - 1.293 - 1.353 0.366 - 280.8 1 2 0 0.0012 8 0 0 0 3.39E+08 3.53E+08 - - - 2.6557 0.9946 230117_WJC_METTL3_WT_vs_EV_F05.16903.16903.2 0.174 12-Jun R.VPFSLLR.G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 830.5014 0.97 40563 16903 2 830.502817 416.258 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3392 - 1.22E+06 - - - 1.6773 - 1.185 0.183 - 108.5 1 2 0 0.0014 7 0 0 0 5.93E+07 6.12E+07 - - - 0.93 0.9918 230117_WJC_METTL3_WT_vs_EV_F05.16904.16904.2 5.09 12-Jul R.VPFSLLR[166.11].G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 840.5097 0.92 40564 16904 2 840.511104 421.2621 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3392.1 - 1.19E+06 - - - 1.6776 - 1.221 0.13 - 220.9 1 2 0 0.0014 7 0 0 0 5.96E+07 6.46E+07 - - - 0.6334 0.9286 230117_WJC_METTL3_WT_vs_EV_F05.16906.16906.2 0.00254 22-Jun R.IINEPTAAAIAY.G "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 16 1245.6605 - 40566 16906 2 1245.663275 623.8375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4 3392.3 - 835140 - - - 2.2245 - 1.519 0.337 - 74.9 1 1 0 0.0028 12 0 0 0 - - - - - 2.6292 1 230117_WJC_METTL3_WT_vs_EV_F05.16907.16907.2 7.31E-06 18-Dec K.VTDAIVLLDR.E "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1113.6394 2.71 40567 16907 2 1113.641416 557.827 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.21 3392.5 - 773061 - - - 1.8336 - 2.827 0.493 - 621.5 1 2 0 0.002 10 0 0 0 1.54E+08 5.68E+07 - - - 5.5824 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.16908.16908.2 8.22E-06 18-Dec K.VFEVMLATDR[166.11].S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1189.6041 1.56 40568 16908 2 1189.606258 595.8093 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3392.6 - 573574 - - - 1.8435 - 2.368 0.421 - 688 1 2 0 0.0022 10 0 0 0 1.68E+07 1.08E+07 - - - 4.556 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.16911.16911.2 0.0148 20-Jul K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.11 40570 16911 2 1235.762566 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3392.9 - 942415 - - - 1.9486 - 1.68 0.317 - 184.5 1 2 0 0.0024 11 0 0 0 7.43E+06 6.70E+06 - - - 2.7851 1 230117_WJC_METTL3_WT_vs_EV_F05.16914.16914.2 8.82E-05 18-Dec K.VTDAIVLLDR[166.11].E "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1123.6476 2.71 40572 16914 2 1123.649614 562.8311 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.21 3393.2 - 1.60E+06 - - - 1.7532 - 2.485 0.427 - 628.3 1 2 0 0.002 10 0 0 0 1.54E+08 5.68E+07 - - - 4.7351 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.16915.16915.2 0.00255 14-Aug K.MFGMVLEK[136.11].L sp|P55060|XPO2_HUMAN 1 961.4856 2.42 40573 16915 2 961.487805 481.7501 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.75 3393.3 - 1.61E+06 - - - 2.2455 - 1.539 0.377 - 156.7 1 2 0 0.0022 8 0 0 0 5.39E+07 2.22E+07 - - - 3.1251 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.16921.16921.2 0.00625 14-Aug R.LWDLVAGK.T "sp|O43660|PLRG1_HUMAN,tr|H0YA24|H0YA24_HUMAN" 2 900.5069 0.97 40578 16921 2 900.508707 451.2607 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 5.84 3394 - 864485 - - - 2.0033 - 1.643 0.323 - 185.5 1 2 0 0.0018 8 0 0 0 5.13E+07 5.29E+07 - - - 2.9236 0.9798 230117_WJC_METTL3_WT_vs_EV_F05.16923.16923.2 0.43 14-May K.MFGMVLEK.L sp|P55060|XPO2_HUMAN 1 953.4714 2.44 40579 16923 2 953.474529 477.743 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.75 3394.2 - 2.40E+06 - - - 3.2334 - 0.96 0.214 - 56.3 1 2 0 0.0031 8 0 0 0 5.70E+07 2.33E+07 - - - 0.4975 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.16928.16928.2 0.379 22-May R.LLLQAGYDPELR.D "sp|Q9BZL4|PP12C_HUMAN,tr|K7EL81|K7EL81_HUMAN" 2 1386.7507 1.21 40584 16928 2 1386.750602 694.3826 Protein phosphatase 1 regulatory subunit 12C OS=Homo sapiens OX=9606 GN=PPP1R12C PE=1 SV=1 4.37 3394.7 - 122971 - - - -0.0822 - 1.185 0.297 - 78.2 1 2 0 -0.0001 12 0 0 0 6.16E+05 5.08E+05 - - - 1.6812 0.9666 230117_WJC_METTL3_WT_vs_EV_F05.16931.16931.2 0.000223 14-Sep K.PFYPALIR.Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 975.5542 0.71 40585 16931 2 975.555702 488.7844 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.18 3395.1 - 711692 - - - 1.5519 - 1.644 0.393 - 340.7 1 1 0 0.0015 8 0 0 0 5.67E+07 7.97E+07 - - - 3.4426 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16933.16933.2 0.00071 14-Aug K.VDLVLLGK[136.11].Q sp|P38117|ETFB_HUMAN 1 863.5572 2.19 40587 16933 2 863.558533 432.7859 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3395.4 - 979008 - - - 1.5969 - 1.852 0.379 - 197.2 1 2 0 0.0014 8 0 0 0 1.69E+08 7.71E+07 - - - 3.6985 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.16935.16935.2 0.000355 20-Sep R.IDGLAALSMDR[166.11].T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1170.5942 1.82 40589 16935 2 1170.594912 586.3044 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3395.7 - 369899 - - - 0.5843 - 2.16 0.403 - 200.1 1 2 0 0.0007 11 0 0 0 1.34E+07 7.37E+06 - - - 4.1007 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.16943.16943.2 0.0871 12-Jun R.DGFGFIK.C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 782.3963 2.07 40595 16943 2 782.398077 392.2054 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3396.7 - 1.83E+06 - - - 2.284 - 1.183 0.223 - 146.9 1 2 0 0.0018 7 0 0 0 6.26E+07 3.02E+07 - - - 1.22 0.9912 230117_WJC_METTL3_WT_vs_EV_F05.16950.16950.2 0.367 12-Jun R.DGFGFIK[136.11].C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 790.4105 2.11 40600 16950 2 790.411816 396.2125 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3397.6 - 1.22E+06 - - - 1.6776 - 1.022 0.236 - 118.1 4 2 0 0.0013 7 0 0 0 6.25E+07 2.96E+07 - - - 0.5837 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16951.16951.2 0.00231 14-Sep K.VDLVLLGK.Q sp|P38117|ETFB_HUMAN 1 855.543 2.2 40601 16951 2 855.545272 428.7788 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3397.7 - 3.34E+06 - - - 2.7094 - 1.977 0.456 - 310.5 1 2 0 0.0023 8 0 0 0 1.69E+08 7.70E+07 - - - 4.4639 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.16953.16953.2 1.28E-05 20-Oct R.IDGLAALSMDR.T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1160.586 1.47 40603 16953 2 1160.587621 581.3003 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3397.9 - 597299 - - - 1.4329 - 2.178 0.336 - 253.8 1 2 0 0.0017 11 0 0 0 1.52E+07 1.03E+07 - - - 3.6279 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.16962.16962.2 0.0924 12-Jul K.SYSLLFR[166.11].V "sp|Q15022|SUZ12_HUMAN,tr|J3QQW9|J3QQW9_HUMAN" 2 894.4839 0.74 40610 16962 2 894.485374 448.2492 Polycomb protein SUZ12 OS=Homo sapiens OX=9606 GN=SUZ12 PE=1 SV=3 8.46 3399.1 - 641788 - - - 1.6781 - 1.385 0.204 - 161.6 1 2 0 0.0015 7 0 0 0 1.24E+07 1.68E+07 - - - 1.5793 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.16967.16967.2 0.00315 12-Jul R.YGDFFIR.Q "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|H0Y7E6|H0Y7E6_HUMAN,tr|B0QY90|B0QY90_HUMAN" 4 916.4443 0.62 40613 16967 2 916.446777 459.2294 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 5.84 3399.7 - 1.53E+06 - - - 2.6996 - 1.423 0.489 - 151.5 1 2 0 0.0025 7 0 0 0 3.44E+07 5.58E+07 - - - 3.7697 0.9298 230117_WJC_METTL3_WT_vs_EV_F05.16968.16968.2 0.000566 18-Nov M.IAGGLFVMDK[136.11].F sp|Q10471|GALT2_HUMAN 1 1057.5722 0.74 40614 16968 2 1057.575865 529.7934 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.84 3399.8 - 1.33E+06 - - - 3.5099 - 2.006 0.364 - 212.1 1 1 0 0.0037 10 0 0 0 1.88E+07 2.53E+07 - - - 3.6715 0.9158 230117_WJC_METTL3_WT_vs_EV_F05.16976.16976.2 5.77 14-Jul R.IAYFTLPK[136.11].T sp|Q92900|RENT1_HUMAN 1 959.5572 1.02 40620 16976 2 959.555905 480.7859 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.59 3400.9 - 743119 - - - -1.3016 - 1.338 0.013 - 89.3 3 2 0 -0.0013 8 0 0 0 3.12E+07 3.06E+07 - - - -0.1983 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.16980.16980.2 0.00261 16-Oct R.FAVGIVIGR.N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 930.5651 1.39 40622 16980 2 930.568719 466.2898 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3401.4 - 3.15E+06 - - - 3.903 - 1.83 0.413 - 403.1 1 2 0 0.0036 9 0 0 0 2.40E+08 1.73E+08 - - - 3.8386 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.16984.16984.2 0.0354 16-Nov R.FAVGIVIGR[166.11].N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 940.5734 1.42 40624 16984 2 940.576029 471.294 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3401.9 - 4.83E+06 - - - 2.8408 - 2.021 0.372 - 455.5 1 2 0 0.0027 9 0 0 0 2.50E+08 1.75E+08 - - - 3.8233 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.16985.16985.2 0.21 16-Jul K.LGVSFSFAK[136.11].K sp|Q9UKJ3|GPTC8_HUMAN 1 962.5317 1.35 40625 16985 2 962.531685 482.2731 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 8.75 3402 - 650086 - - - 0.0177 - 1.56 0.271 - 79.8 1 2 0 0 9 0 0 0 2.09E+07 1.55E+07 - - - 2.3291 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.16987.16987.2 25.1 16-Oct K.RVLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1037.7073 1.32 40627 16987 2 1037.710498 519.8609 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3402.2 - 775513 - - - 3.049 - 1.758 0.238 - 182.4 1 2 0 0.0032 9 0 0 0 1.93E+08 1.47E+08 - - - 2.4301 0.9969 230117_WJC_METTL3_WT_vs_EV_F05.16988.16988.2 0.126 12-Jun K.LFNPLIR.L sp|Q9Y5B6|PAXB1_HUMAN 1 871.528 0.53 40628 16988 2 871.529636 436.7713 PAX3- and PAX7-binding protein 1 OS=Homo sapiens OX=9606 GN=PAXBP1 PE=1 SV=2 9.75 3402.3 - 502896 - - - 1.9081 - 1.328 0.217 - 101.5 2 2 0 0.0017 7 0 0 0 9.78E+06 1.85E+07 - - - 1.4076 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.16997.16997.2 0.0192 14-Jul R.ITVLEALR.H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 913.5597 1.23 40634 16997 2 913.56205 457.7871 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3403.4 - 1.46E+06 - - - 2.6085 - 1.742 0.22 - 169.8 1 2 0 0.0024 8 0 0 0 1.18E+08 9.55E+07 - - - 2.3391 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.16998.16998.2 2.97 16-Nov K.R[166.11]VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1057.7239 1.32 40635 16998 2 1057.72714 529.8692 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3403.5 - 1.59E+06 - - - 3.0878 - 1.783 0.225 - 225.6 1 2 0 0.0033 9 0 0 0 1.93E+08 1.47E+08 - - - 2.3749 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.16999.16999.2 0.000485 13/20 K.ALADVATVLGR.A "sp|Q92542|NICA_HUMAN,tr|H0Y6T7|H0Y6T7_HUMAN" 2 1084.6241 5.06 40636 16999 2 1084.621359 543.3193 Nicastrin OS=Homo sapiens OX=9606 GN=NCSTN PE=1 SV=2 5.88 3403.6 - 458496 - - - -2.4884 - 2.271 0.32 - 413.6 1 2 0 -0.0027 11 0 0 0 1.06E+07 2.10E+06 - - - 3.6226 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17004.17004.2 0.0032 14-Sep R.ITVLEALR[166.11].H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 923.5679 1.23 40639 17004 2 923.569415 462.7912 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3404.2 - 1.56E+06 - - - 1.6003 - 1.821 0.391 - 277.5 1 2 0 0.0015 8 0 0 0 1.18E+08 9.61E+07 - - - 3.7362 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17005.17005.2 0.162 16-Oct K.AILVVFANK.Q "sp|P40616|ARL1_HUMAN,tr|B4DZG7|B4DZG7_HUMAN,tr|F8VYN9|F8VYN9_HUMAN" 3 973.5961 0.34 40640 17005 2 973.598848 487.8053 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 8.8 3404.3 - 899976 - - - 2.8708 - 2.075 0.315 - 318.1 1 2 0 0.0028 9 0 0 0 7.11E+07 2.11E+08 - - - 3.4785 0.9745 230117_WJC_METTL3_WT_vs_EV_F05.17009.17009.2 0.00385 16-Aug F.VLVLYDEIK.K "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 3 1090.6274 0.14 40642 17009 2 1090.628558 546.321 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 4.37 3404.8 - 1.28E+06 - - - 1.0508 - 1.883 0.417 - 186.2 1 1 0 0.0011 9 0 0 0 1.67E+07 1.20E+08 - - - 3.9515 0.9875 230117_WJC_METTL3_WT_vs_EV_F05.17011.17011.2 3.12 14-Jul R.LLLAALGR[166.11].R "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 835.5519 1.43 40644 17011 2 835.552814 418.7832 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 9.75 3405.1 - 293214 - - - 1.1023 - 1.247 0.084 - 130.4 1 2 0 0.0009 8 0 0 0 5.92E+07 4.14E+07 - - - 0.3269 0.9733 230117_WJC_METTL3_WT_vs_EV_F05.17012.17012.2 3.51 16-Jun R.VLIFSQMTR[166.11].V "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 1103.6037 0.95 40645 17012 2 1103.603934 552.8091 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 9.72 3405.2 - 205116 - - - 0.2383 - 1.207 0.054 - 78 1 2 0 0.0003 9 0 0 0 1.78E+07 1.87E+07 - - - -0.0159 0.996 230117_WJC_METTL3_WT_vs_EV_F05.17017.17017.2 0.0249 14-Jul R.IAYFTLPK.T sp|Q92900|RENT1_HUMAN 1 951.543 0.99 40649 17017 2 951.547139 476.7788 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.59 3405.7 - 1.59E+06 - - - 4.3981 - 1.408 0.334 - 127 1 2 0 0.0042 8 0 0 0 3.65E+07 3.70E+07 - - - 2.5386 0.9946 230117_WJC_METTL3_WT_vs_EV_F05.17026.17026.2 0.564 14-Aug K.AGISFIIK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 847.5167 0.87 40656 17026 2 847.51843 424.7656 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.8 3406.7 - 425395 - - - 1.9941 - 1.249 0.174 - 118.4 1 2 0 0.0017 8 0 0 0 1.86E+09 2.15E+09 - - - 0.9962 0.9203 230117_WJC_METTL3_WT_vs_EV_F05.17033.17033.2 1.26 18-Aug R.LLDYVPIGPR[166.11].F "sp|P46459|NSF_HUMAN,tr|K7EQD6|K7EQD6_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 4 1151.6578 1.79 40662 17033 2 1151.666054 576.8362 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.84 3407.6 - 318929 - - - 7.154 - 1.655 0.125 - 173.1 1 2 0 0.0082 10 0 0 0 3.67E+07 2.05E+07 - - - 1.3679 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.17034.17034.2 0.0547 18-Nov R.LLDYVPIGPR.F "sp|P46459|NSF_HUMAN,tr|K7EQD6|K7EQD6_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 4 1141.6495 1.71 40663 17034 2 1141.652469 571.832 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.84 3407.7 - 408566 - - - 2.5612 - 1.926 0.289 - 344.3 1 2 0 0.0029 10 0 0 0 4.03E+07 2.36E+07 - - - 3.0042 0.8803 230117_WJC_METTL3_WT_vs_EV_F05.17035.17035.2 4.95 22-May K.LIETFSPTESLR.M sp|A6NGG8|PCARE_HUMAN 1 1391.7296 1.94 40664 17035 2 1391.726709 696.8721 Photoreceptor cilium actin regulator OS=Homo sapiens OX=9606 GN=PCARE PE=1 SV=1 4.53 3407.8 - 181798 - - - -2.1103 - 1.386 0.04 - 31.8 5 2 0 -0.0029 12 0 0 0 1.41E+07 7.23E+06 - - - -0.1178 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.17039.17039.2 0.00425 18-Oct R.LGGIGQFLAK[136.11].A sp|Q08211|DHX9_HUMAN 1 1010.6004 0.86 40666 17039 2 1010.604061 506.3075 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3408.4 - 760956 - - - 3.6068 - 2.071 0.321 - 193.2 1 2 0 0.0036 10 0 0 0 3.02E+08 3.51E+08 - - - 3.4429 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.17040.17040.2 0.00139 14-Oct K.LMNLWTER.F "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1061.5328 0.35 40667 17040 2 1061.537055 531.7737 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 3408.4 - 2.49E+06 - - - 4.0074 - 1.771 0.386 - 456.4 1 2 0 0.0043 8 0 0 0 2.34E+08 6.59E+08 - - - 3.6144 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.17041.17041.2 0.0052 14-Aug K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 0.99 40668 17041 2 988.572133 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3408.6 - 1.39E+06 - - - 1.5851 - 1.676 0.323 - 251.2 1 2 0 0.0016 8 0 0 0 2.13E+08 2.15E+08 - - - 2.9837 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.17043.17043.2 0.0732 18-Aug R.VLISTDVWAR[166.11].G "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1168.648 0.96 40670 17043 2 1168.650454 585.3313 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.81 3408.8 - 768075 - - - 2.1187 - 1.688 0.258 - 107.8 1 2 0 0.0025 10 0 0 0 1.38E+08 1.44E+08 - - - 2.4072 0.9804 230117_WJC_METTL3_WT_vs_EV_F05.17044.17044.2 0.543 12-Jul K.LYLVFSK.E sp|P57740|NU107_HUMAN 1 868.5058 1.08 40671 17044 2 868.509455 435.2602 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 8.59 3408.9 - 463989 - - - 4.1612 - 1.386 0.121 - 133.3 1 2 0 0.0036 7 0 0 0 1.08E+07 1.00E+07 - - - 0.9679 0.999 230117_WJC_METTL3_WT_vs_EV_F05.17045.17045.2 0.0491 12-Jul K.ISFELMR.E "sp|Q9UNE7|CHIP_HUMAN,tr|H3BUD0|H3BUD0_HUMAN,tr|H3BTA3|H3BTA3_HUMAN" 3 894.4633 6.58 40672 17045 2 894.46388 448.2389 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 6 3409.1 - 796650 - - - 0.6216 - 1.539 0.284 - 117.2 1 2 0 0.0006 7 0 0 0 2.71E+07 4.12E+06 - - - 2.5045 0.9912 230117_WJC_METTL3_WT_vs_EV_F05.17048.17048.2 0.241 12-May K.GLLDDLR[166.11].N sp|Q07065|CKAP4_HUMAN 1 810.4475 1.29 40675 17048 2 810.449779 406.231 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.21 3409.5 - 151284 - - - 2.8268 - 1.073 0.225 - 76 1 2 0 0.0023 7 0 0 0 3.35E+07 2.59E+07 - - - 0.9254 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.17053.17053.2 0.00575 14-Jun K.AVPSWFVR.V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 960.5181 1.8 40677 17053 2 960.520801 481.2663 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3410 - 2.48E+06 - - - 2.7735 - 1.368 0.339 - 103.9 1 2 0 0.0027 8 0 0 0 8.84E+07 4.90E+07 - - - 2.4891 0.9818 230117_WJC_METTL3_WT_vs_EV_F05.17056.17056.2 0.667 14-Jul R.EILETLIK[136.11].G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 965.5888 1.64 40680 17056 2 965.592313 483.8017 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3410.3 - 1.68E+06 - - - 3.5874 - 1.481 0.069 - 167.9 1 2 0 0.0035 8 0 0 0 1.91E+08 1.16E+08 - - - 0.734 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.17063.17063.2 0.0329 16-Sep K.SSLNPILFR.G "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1045.592 1.27 40685 17063 2 1045.59437 523.8033 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 9.47 3411.2 - 3.45E+06 - - - 2.238 - 1.884 0.254 - 291.7 1 2 0 0.0023 9 0 0 0 1.25E+08 9.91E+07 - - - 2.7488 1 230117_WJC_METTL3_WT_vs_EV_F05.17064.17064.2 6.58E-05 16-Oct F.ADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 952.5957 12.55 40686 17064 2 952.597262 477.3051 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3411.3 - 2.81E+06 - - - 1.6208 - 1.957 0.49 - 293.1 1 1 0 0.0015 9 0 0 0 4.10E+07 3.27E+06 - - - 4.6021 0.9964 230117_WJC_METTL3_WT_vs_EV_F05.17066.17066.2 0.174 18-Aug R.IFLPPPPGIR.K "sp|Q8IX18|DHX40_HUMAN,tr|F5H625|F5H625_HUMAN" 2 1105.6648 1.63 40688 17066 2 1105.667632 553.8397 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 9.75 3411.6 - 693277 - - - 2.5605 - 1.345 0.222 - 126.9 1 2 0 0.0028 10 0 0 0 1.18E+07 7.21E+06 - - - 1.5071 0.9252 230117_WJC_METTL3_WT_vs_EV_F05.17071.17071.2 1.34 14-Jul R.IASFLQLK.N "sp|P42694|HELZ_HUMAN,tr|J3KT20|J3KT20_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 4 918.5539 0.62 40691 17071 2 918.560378 460.2842 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.75 3412.1 - 522004 - - - 7.1025 - 1.603 0.127 - 87.5 1 2 0 0.0065 8 0 0 0 3.46E+07 5.58E+07 - - - 1.4001 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.17072.17072.2 0.00564 18-Aug R.LGGIGQFLAK.A sp|Q08211|DHX9_HUMAN 1 1002.5862 0.82 40692 17072 2 1002.587053 502.3004 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3412.2 - 1.82E+06 - - - 0.8348 - 1.458 0.281 - 124.4 1 2 0 0.0008 10 0 0 0 3.02E+08 3.67E+08 - - - 2.1687 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.17073.17073.2 0.0105 14-Jul K.AVPSWFVR[166.11].V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 970.5264 2.55 40693 17073 2 970.526645 486.2705 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3412.2 - 1.32E+06 - - - 0.2452 - 1.407 0.268 - 220.1 1 2 0 0.0002 8 0 0 0 1.33E+08 5.23E+07 - - - 2.0502 0.9898 230117_WJC_METTL3_WT_vs_EV_F05.17075.17075.2 1.5 14-Jul R.LLLAALGR.R "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 825.5436 1.45 40695 17075 2 825.544435 413.7791 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 9.75 3412.3 - 952435 - - - 0.9836 - 1.274 0.096 - 117.9 1 2 0 0.0008 8 0 0 0 6.02E+07 4.15E+07 - - - 0.4801 0.9918 230117_WJC_METTL3_WT_vs_EV_F05.17076.17076.2 0.116 12-Jul K.EGIILFK.E sp|P05455|LA_HUMAN 1 818.4902 1.01 40696 17076 2 818.491762 410.2524 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 6.1 3412.5 - 542922 - - - 1.9194 - 1.374 0.084 - 155.7 1 2 0 0.0016 7 0 0 0 8.60E+07 8.51E+07 - - - 0.6677 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17078.17078.2 0.00104 16-Oct K.LNNLVLFDK[136.11].A sp|P62851|RS25_HUMAN 1 1082.6215 1.02 40698 17078 2 1082.622168 542.318 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3412.6 - 264119 - - - 0.5745 - 2.329 0.366 - 302.4 1 2 0 0.0006 9 0 0 0 6.23E+08 6.13E+08 - - - 4.19 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17084.17084.2 0.00129 16-Aug R.AGFVPVYLR[166.11].Q "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1030.5839 0.69 40702 17084 2 1030.58512 516.2992 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 8.79 3413.4 - 3.27E+06 - - - 1.1624 - 1.583 0.444 - 207.3 1 2 0 0.0012 9 0 0 0 4.48E+07 6.46E+07 - - - 3.6488 0.8987 230117_WJC_METTL3_WT_vs_EV_F05.17092.17092.2 0.761 12-Jul K.GLLDDLR.N sp|Q07065|CKAP4_HUMAN 1 800.4392 1.31 40708 17092 2 800.443579 401.2269 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.21 3414.3 - 735632 - - - 5.4483 - 1.153 0.118 - 215.8 1 2 0 0.0044 7 0 0 0 3.38E+07 2.58E+07 - - - 0.3623 0.9454 230117_WJC_METTL3_WT_vs_EV_F05.17096.17096.2 0.00674 20-Aug R.QLYHLGVVEAY.S sp|Q08211|DHX9_HUMAN 1 1290.6608 - 40710 17096 2 1290.664054 646.3377 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.24 3414.8 - 916792 - - - 2.4917 - 1.538 0.398 - 156.2 1 1 0 0.0032 11 0 0 0 - - - - - 3.1442 0.999 230117_WJC_METTL3_WT_vs_EV_F05.17099.17099.2 0.0486 26-Oct R.LGGIPVGVVAVETR.T "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 1365.798 2.85 40713 17099 2 1365.802574 683.9063 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 6 3415.1 - 340402 - - - 3.349 - 1.769 0.393 - 267.6 1 2 0 0.0046 14 0 0 0 3.16E+06 1.11E+06 - - - 3.3737 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17103.17103.2 0.00938 18-Sep K.VALDLDPYVK.K sp|O95295|SNAPN_HUMAN 1 1131.6176 2.24 40715 17103 2 1131.619489 566.8161 SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN PE=1 SV=1 4.21 3415.7 - 1.75E+06 - - - 1.6905 - 2.051 0.404 - 237.4 1 2 0 0.0019 10 0 0 0 2.77E+07 1.24E+07 - - - 4.0294 0.9928 230117_WJC_METTL3_WT_vs_EV_F05.17107.17107.2 0.0268 14-Aug K.GWGLLGPR[166.11].N "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 864.4845 0.91 40717 17107 2 864.483562 433.2495 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 9.75 3416.2 - 389743 - - - -1.1336 - 1.582 0.151 - 243.3 1 2 0 -0.001 8 0 0 0 1.82E+07 1.99E+07 - - - 1.5394 0.9943 230117_WJC_METTL3_WT_vs_EV_F05.17109.17109.2 2.25 14-Jul R.EILETLIK.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 957.5746 1.64 40719 17109 2 957.576738 479.7946 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3416.4 - 9.10E+06 - - - 2.1816 - 1.467 0.11 - 184.6 1 2 0 0.0021 8 0 0 0 1.91E+08 1.16E+08 - - - 1.0086 0.9914 230117_WJC_METTL3_WT_vs_EV_F05.17110.17110.2 0.179 14-Jun R.VIPLPQWK.A sp|Q96ES7|SGF29_HUMAN 1 979.5855 1.86 40720 17110 2 979.588861 490.8 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 8.72 3416.5 - 633326 - - - 3.4433 - 1.07 0.269 - 92.3 1 2 0 0.0034 8 0 0 0 2.31E+07 1.24E+07 - - - 1.2308 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.17112.17112.2 0.0368 22-Sep -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 1.22 40722 17112 2 1306.769053 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3416.8 - 277225 - - - 0.5915 - 1.563 0.226 - 145.2 1 2 0 0.0008 12 0 0 0 1.37E+07 1.11E+07 - - - 1.8851 0.892 230117_WJC_METTL3_WT_vs_EV_F05.17113.17113.2 0.208 16-Aug R.FGIWTGEYK[136.11].C sp|Q9NUD5|ZCHC3_HUMAN 1 1107.548 1.91 40723 17113 2 1107.556049 554.7813 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 6 3416.9 - 253528 - - - 7.2259 - 1.138 0.233 - 109.4 1 2 0 0.008 9 0 0 0 1.49E+07 7.79E+06 - - - 1.1334 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17118.17118.2 0.0209 16-Sep K.LNNLVLFDK.A sp|P62851|RS25_HUMAN 1 1074.6073 1.02 40726 17118 2 1074.608653 538.3109 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3417.6 - 5.90E+07 - - - 1.2163 - 2.274 0.353 - 283.3 1 2 0 0.0013 9 0 0 0 6.23E+08 6.13E+08 - - - 4.0246 0.9911 230117_WJC_METTL3_WT_vs_EV_F05.17121.17121.2 0.57 12-Aug K.YLELFQR[166.11].Q "sp|Q9UBQ6|EXTL2_HUMAN,tr|C9JEG3|C9JEG3_HUMAN" 2 977.521 0.94 40729 17121 2 977.51975 489.7678 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 6 3417.9 - 1.04E+06 - - - -1.2654 - 1.535 0.141 - 246.7 1 2 0 -0.0012 7 0 0 0 7.00E+06 7.43E+06 - - - 1.4399 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.17134.17134.2 0.0218 14-Aug K.LFDFVNAK.K "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 952.5018 0.51 40740 17134 2 952.503716 477.2582 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 5.84 3419.4 - 1.05E+06 - - - 1.9926 - 1.459 0.357 - 133.2 1 2 0 0.0019 8 0 0 0 4.49E+07 8.73E+07 - - - 2.8165 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17136.17136.2 0.0162 14-Jul K.LFIGMISK.K "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 907.5201 1.29 40742 17136 2 907.521668 454.7673 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.75 3419.6 - 534134 - - - 1.7157 - 1.444 0.369 - 115.3 1 2 0 0.0016 8 0 0 0 6.36E+06 4.91E+06 - - - 2.8741 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.17138.17138.2 0.00896 14-Sep R.TFLVPEIK.S sp|Q9P1Y5|CAMP3_HUMAN 1 945.5535 0.91 40744 17138 2 945.553507 473.784 Calmodulin-regulated spectrin-associated protein 3 OS=Homo sapiens OX=9606 GN=CAMSAP3 PE=1 SV=2 5.66 3419.9 - 474678 - - - -0.0127 - 1.472 0.33 - 290.4 1 2 0 0 8 0 0 0 9.60E+06 1.06E+07 - - - 2.6444 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17146.17146.2 5.71E-05 14-Aug K.MVGFIIGR.G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 891.5 1.41 40750 17146 2 891.500094 446.7573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3420.9 - 7.38E+06 - - - 0.0561 - 1.726 0.525 - 228.7 1 2 0 0.0001 8 0 0 0 3.94E+08 2.79E+08 - - - 4.5648 0.8825 230117_WJC_METTL3_WT_vs_EV_F05.17147.17147.2 0.0158 22-Jun R.VINEPTAAALAY.G "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1231.6449 - 40751 17147 2 1231.647414 616.8297 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4 3421 - 1.92E+06 - - - 2.0793 - 1.386 0.303 - 71.8 2 1 0 0.0026 12 0 0 0 - - - - - 2.0026 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.17149.17149.2 0.0135 22-Aug R.IVPGQFLAVDPK.G sp|Q15393|SF3B3_HUMAN 1 1282.7285 1.27 40753 17149 2 1282.73193 642.3715 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3421.2 - 534622 - - - 2.6553 - 1.689 0.418 - 150 1 2 0 0.0034 12 0 0 0 2.29E+07 1.80E+07 - - - 3.5064 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17151.17151.2 2.56E-05 22-Aug R.IVPGQFLAVDPK[136.11].G sp|Q15393|SF3B3_HUMAN 1 1290.7427 1.27 40755 17151 2 1290.744512 646.3786 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3421.5 - 401961 - - - 1.3852 - 1.847 0.423 - 109 1 2 0 0.0018 12 0 0 0 2.29E+07 1.80E+07 - - - 3.7791 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.17157.17157.2 0.00839 20-Aug R.LYPVLQQSLVR[166.11].A sp|Q5RKV6|EXOS6_HUMAN 1 1324.7742 0.92 40759 17157 2 1324.778041 663.3944 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.75 3422.3 - 1.03E+06 - - - 2.8677 - 1.623 0.357 - 149.6 2 2 0 0.0038 11 0 0 0 4.77E+07 5.21E+07 - - - 2.8522 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17158.17158.2 0.00185 24-Oct K.LLPHQLYGVVPQA.- "sp|P18887|XRCC1_HUMAN,tr|F5H8D7|F5H8D7_HUMAN" 2 1433.8031 - 40760 17158 2 1433.805954 717.9088 DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2 6.74 3422.4 - 245784 - - - 2.001 - 1.965 0.463 - 203.7 1 2 0 0.0029 13 0 0 0 - - - - - 4.1935 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.17162.17162.2 0.0971 20-Jul K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.72 40764 17162 2 1245.770529 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3422.9 - 295487 - - - 1.6865 - 1.486 0.266 - 110.6 1 2 0 0.0021 11 0 0 0 2.56E+07 1.49E+07 - - - 2.0765 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.17166.17166.2 0.0152 18-Sep R.LINLVGESLR.L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1112.6554 4.75 40767 17166 2 1112.657042 557.335 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6 3423.4 - 285416 - - - 1.5126 - 1.768 0.225 - 194.3 1 2 0 0.0017 10 0 0 0 9.10E+07 1.92E+07 - - - 2.2929 0.9548 230117_WJC_METTL3_WT_vs_EV_F05.17171.17171.2 1.75 12-May R.DFYFSVK[136.11].L sp|Q9NY12|GAR1_HUMAN 1 912.4473 0.69 40771 17171 2 912.447964 457.2309 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3423.8 - 1.02E+06 - - - 0.7606 - 1.071 0.035 - 99.1 1 2 0 0.0007 7 0 0 0 6.52E+07 9.49E+07 - - - -0.4834 1 230117_WJC_METTL3_WT_vs_EV_F05.17175.17175.2 1.64E-06 16-Sep R.TFTNVYWMK.V sp|Q9HBH1|DEFM_HUMAN 1 1188.5638 1.19 40775 17175 2 1188.566165 595.2892 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 8.26 3424 - 624310 - - - 2.0184 - 1.943 0.513 - 240.5 1 2 0 0.0024 9 0 0 0 6.50E+06 5.45E+06 - - - 4.7509 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17176.17176.2 0.0319 14-Nov R.IVEVLLMK.D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 943.5776 1.01 40776 17176 2 943.579905 472.7961 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3424.1 - 554646 - - - 2.4163 - 2.15 0.38 - 363.3 1 2 0 0.0023 8 0 0 0 3.18E+08 3.14E+08 - - - 4.1556 1 230117_WJC_METTL3_WT_vs_EV_F05.17178.17178.2 0.00183 16-Sep R.TFTNVYWMK[136.11].V sp|Q9HBH1|DEFM_HUMAN 1 1196.578 1.19 40778 17178 2 1196.581237 599.2963 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 8.26 3424.3 - 536664 - - - 2.7336 - 1.975 0.527 - 236.7 1 2 0 0.0033 9 0 0 0 6.50E+06 5.45E+06 - - - 4.9013 1 230117_WJC_METTL3_WT_vs_EV_F05.17179.17179.2 0.00115 24-Dec K.LLLGAGAVAYGVR.E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1258.7398 1.36 40779 17179 2 1258.743315 630.3772 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3424.4 - 367404 - - - 2.8266 - 2.326 0.475 - 453.3 1 2 0 0.0036 13 0 0 0 1.09E+08 8.00E+07 - - - 4.7148 0.9954 230117_WJC_METTL3_WT_vs_EV_F05.17180.17180.2 0.132 18-Sep -.MLIEDVDALK.S "sp|Q9P2N5|RBM27_HUMAN,tr|U3KPZ7|U3KPZ7_HUMAN" 2 1145.6002 0.53 40780 17180 2 1145.605706 573.8074 RNA-binding protein 27 OS=Homo sapiens OX=9606 GN=RBM27 PE=1 SV=2 4.03 3424.4 - 276758 - - - 4.7966 - 1.776 0.276 - 216.1 1 2 0 0.0055 10 0 0 0 6.90E+06 1.31E+07 - - - 2.681 0.9964 230117_WJC_METTL3_WT_vs_EV_F05.17181.17181.2 0.033 16-Jun R.LLFNDPDLR[166.11].E sp|Q9NRR4|RNC_HUMAN 1 1111.5901 0.34 40781 17181 2 1111.590156 556.8023 Ribonuclease 3 OS=Homo sapiens OX=9606 GN=DROSHA PE=1 SV=2 4.21 3424.5 - 209117 - - - 0.0243 - 1.283 0.239 - 75.3 1 2 0 0 9 0 0 0 9.63E+05 2.84E+06 - - - 1.5272 0.9651 230117_WJC_METTL3_WT_vs_EV_F05.17183.17183.2 0.456 18-Jul K.VIPYIASQFR[166.11].K sp|Q9NU22|MDN1_HUMAN 1 1202.6687 0.29 40783 17183 2 1202.665982 602.3416 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 8.72 3424.7 - 169913 - - - -2.2716 - 1.379 0.124 - 90.8 1 2 0 -0.0027 10 0 0 0 2.07E+06 7.18E+06 - - - 0.853 1 230117_WJC_METTL3_WT_vs_EV_F05.17185.17185.2 8.68E-05 14-Sep K.MVGFIIGR[166.11].G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 901.5083 1.42 40784 17185 2 901.509438 451.7614 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3425 - 4.94E+07 - - - 1.2468 - 1.868 0.539 - 307.2 1 2 0 0.0011 8 0 0 0 3.96E+08 2.79E+08 - - - 4.9063 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.17187.17187.2 0.2 14-Oct R.IVEVLLMK[136.11].D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 951.5918 1.01 40785 17187 2 951.594414 476.8032 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3425.2 - 7.30E+06 - - - 2.7207 - 2.159 0.217 - 256 1 2 0 0.0026 8 0 0 0 3.18E+08 3.14E+08 - - - 2.9642 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.17188.17188.2 0.0116 14-Sep R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 999 40786 17188 2 1000.562104 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3425.2 - 3.21E+06 - - - 2.7695 - 1.737 0.312 - 256.4 1 2 0 0.0028 8 0 0 0 7.55E+07 0.00E+00 - - - 3.0098 1 230117_WJC_METTL3_WT_vs_EV_F05.17189.17189.2 5.28E-05 14/24 K.LLLGAGAVAYGVR[166.11].E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1268.748 1.36 40787 17189 2 1268.750766 635.3813 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3425.3 - 4.56E+06 - - - 2.1588 - 2.556 0.497 - 656.4 1 2 0 0.0027 13 0 0 0 1.09E+08 8.00E+07 - - - 5.1195 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17190.17190.2 0.00361 18-Nov K.VVDLLAPYAK[136.11].G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1095.6419 1.65 40788 17190 2 1095.6448 548.8282 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3425.3 - 1.70E+06 - - - 2.604 - 2.082 0.469 - 439 1 2 0 0.0029 10 0 0 0 6.60E+08 3.99E+08 - - - 4.5511 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17191.17191.2 0.000127 18-Nov K.VVDDEIYYFR.K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1317.6241 2.03 40789 17191 2 1317.626213 659.8193 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3425.4 - 1.52E+06 - - - 1.59 - 1.972 0.472 - 392.5 1 2 0 0.0021 10 0 0 0 1.92E+07 9.42E+06 - - - 4.422 0.8624 230117_WJC_METTL3_WT_vs_EV_F05.17195.17195.2 0.971 20-Sep K.LPVSVPMPIAR.P "sp|Q9Y6R4|M3K4_HUMAN,tr|J3KNB8|J3KNB8_HUMAN,tr|F5H1X6|F5H1X6_HUMAN,tr|F5H538|F5H538_HUMAN,tr|F5H4R1|F5H4R1_HUMAN" 5 1178.6845 4.02 40793 17195 2 1178.685406 590.3496 Mitogen-activated protein kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP3K4 PE=1 SV=2 9.75 3425.9 - 345099 - - - 0.7262 - 1.743 0.169 - 199.7 1 1 0 0.0009 11 0 0 0 1.54E+06 3.83E+05 - - - 1.792 1 230117_WJC_METTL3_WT_vs_EV_F05.17201.17201.2 0.0271 18-Dec K.VVDLLAPYAK.G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1087.6277 1.65 40797 17201 2 1087.629747 544.8211 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3426.7 - 1.27E+07 - - - 1.8389 - 2.459 0.454 - 542.4 1 2 0 0.002 10 0 0 0 6.58E+08 3.99E+08 - - - 4.9051 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.17202.17202.2 0.261 14-Jul R.LLNIWQER.S sp|Q9NQG5|RPR1B_HUMAN 1 1070.5873 2.96 40798 17202 2 1070.589761 536.3009 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 6 3426.7 - 3.97E+06 - - - 2.3184 - 1.779 0.092 - 168.8 1 2 0 0.0025 8 0 0 0 8.04E+07 2.71E+07 - - - 1.4571 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17203.17203.2 0.149 16-Sep R.AFLGQVLVR.R "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1001.6022 0.36 40799 17203 2 1001.604241 501.8084 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 9.79 3426.8 - 4.82E+06 - - - 2.0367 - 1.804 0.418 - 222.9 1 2 0 0.002 9 0 0 0 1.02E+08 2.80E+08 - - - 3.8346 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.17207.17207.2 0.018 16-Aug K.LESIASVFK.D sp|Q9UKJ3|GPTC8_HUMAN 1 992.5542 0.09 40803 17207 2 992.553439 497.2844 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 6 3427.2 - 722887 - - - -0.8141 - 1.535 0.284 - 106.6 2 2 0 -0.0008 9 0 0 0 4.64E+06 5.31E+07 - - - 2.2437 0.9545 230117_WJC_METTL3_WT_vs_EV_F05.17211.17211.2 0.246 16-Jun R.MLPPPPMWR.R "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 5 1123.5671 0.74 40807 17211 2 1123.570715 562.7908 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 9.5 3427.7 - 525812 - - - 3.237 - 1.217 0.045 - 108.5 1 2 0 0.0036 9 0 0 0 2.10E+07 2.84E+07 - - - -0.0596 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.17212.17212.2 0.429 12-Jul R.VLFSLVK.R "sp|Q14999|CUL7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 2 804.5109 1.01 40808 17212 2 804.512597 403.2627 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 8.72 3427.8 - 455606 - - - 2.077 - 1.487 0.167 - 166.7 1 2 0 0.0017 7 0 0 0 6.59E+06 6.55E+06 - - - 1.5311 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.17213.17213.2 0.897 12-Jun R.VLFSLVK[136.11].R "sp|Q14999|CUL7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 2 812.5251 1.08 40809 17213 2 812.526987 407.2698 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 8.72 3428 - 416948 - - - 2.2904 - 1.462 0.17 - 93.7 1 2 0 0.0019 7 0 0 0 6.49E+06 6.03E+06 - - - 1.4995 0.9244 230117_WJC_METTL3_WT_vs_EV_F05.17214.17214.2 0.00179 20-Sep W.TPAALIPEALR.E sp|Q8IVL6|P3H3_HUMAN 1 1150.671 0.99 40810 17214 2 1150.674896 576.3428 Prolyl 3-hydroxylase 3 OS=Homo sapiens OX=9606 GN=P3H3 PE=1 SV=1 5.66 3428.1 - 320292 - - - 3.378 - 1.629 0.412 - 188.9 1 1 0 0.0039 11 0 0 0 2.95E+06 2.97E+06 - - - 3.4029 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.17219.17219.2 0.0136 12-Jun R.DFYFSVK.L sp|Q9NY12|GAR1_HUMAN 1 904.4331 0.69 40813 17219 2 904.43554 453.2238 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3428.7 - 5.46E+06 - - - 2.731 - 1.059 0.336 - 148.4 1 2 0 0.0025 7 0 0 0 6.52E+07 9.51E+07 - - - 1.7036 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.17220.17220.2 0.0222 14-Aug R.LLNIWQER[166.11].S sp|Q9NQG5|RPR1B_HUMAN 1 1080.5955 3.17 40814 17220 2 1080.597236 541.3051 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 6 3428.8 - 1.99E+06 - - - 1.5612 - 1.884 0.265 - 244 1 2 0 0.0017 8 0 0 0 7.90E+07 2.49E+07 - - - 2.9081 1 230117_WJC_METTL3_WT_vs_EV_F05.17222.17222.2 0.00446 16-Dec R.TPLDLAAFK[136.11].G "sp|O15084|ANR28_HUMAN,tr|B4DIW9|B4DIW9_HUMAN" 2 982.5579 1.76 40816 17222 2 982.558795 492.2862 Serine\threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5 5.5 3429 - 702051 - - - 0.9282 - 2.226 0.466 - 479.3 1 2 0 0.0009 9 0 0 0 1.99E+07 1.13E+07 - - - 4.7976 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.17223.17223.2 3.53E-05 18-Nov K.VVDDEIYYFR[166.11].K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1327.6324 2.03 40817 17223 2 1327.637649 664.8235 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3429.2 - 741419 - - - 3.9627 - 2.096 0.471 - 399.5 1 2 0 0.0053 10 0 0 0 1.92E+07 9.42E+06 - - - 4.5838 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17224.17224.2 3.69E-06 15/22 R.YVVGVLEAAGVR[166.11].Y sp|Q9H9S5|FKRP_HUMAN 1 1241.7007 0.36 40818 17224 2 1241.701097 621.8576 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 6 3429.2 - 549605 - - - 0.2859 - 2.547 0.413 - 762.8 1 2 0 0.0004 12 0 0 0 6.45E+06 1.80E+07 - - - 4.5512 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.17226.17226.2 8.69E-05 18-Nov K.WVGVILDEAK.G "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1128.6179 2.65 40820 17226 2 1128.622932 565.3162 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3429.5 - 429593 - - - 4.4497 - 2.163 0.422 - 303.9 1 2 0 0.005 10 0 0 0 1.79E+08 6.75E+07 - - - 4.3098 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17228.17228.2 0.00336 22-Dec K.VLAGVLDSVDVR[166.11].L "sp|Q8NCH0|CHSTE_HUMAN,tr|H0YN65|H0YN65_HUMAN" 2 1251.7062 3.21 40822 17228 2 1251.709573 626.8604 Carbohydrate sulfotransferase 14 OS=Homo sapiens OX=9606 GN=CHST14 PE=1 SV=2 4.21 3429.7 - 163196 - - - 2.6771 - 2.232 0.385 - 563.7 1 2 0 0.0034 12 0 0 0 1.63E+07 5.09E+06 - - - 3.9961 0.8754 230117_WJC_METTL3_WT_vs_EV_F05.17233.17233.2 1.98 12-Aug N.IC[160.03]LDILK[136.11].E "sp|O00762|UBE2C_HUMAN,sp|P61086|UBE2K_HUMAN,sp|P61088|UBE2N_HUMAN,sp|Q96LR5|UB2E2_HUMAN,sp|P51965|UB2E1_HUMAN,sp|Q969T4|UB2E3_HUMAN,sp|Q92785|REQU_HUMAN,tr|F8VSD4|F8VSD4_HUMAN,tr|B7Z306|B7Z306_HUMAN,tr|R4GND1|R4GND1_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN,tr|H7C061|H7C061_HUMAN,tr|F8VQQ8|F8VQQ8_HUMAN,tr|F8VV71|F8VV71_HUMAN,tr|A0A1B0GX65|A0A1B0GX65_HUMAN,tr|A0A087X283|A0A087X283_HUMAN,tr|H0YEI1|H0YEI1_HUMAN,tr|C9J2P0|C9J2P0_HUMAN" 18 881.5136 1.6 40825 17233 2 881.51483 441.7641 Ubiquitin-conjugating enzyme E2 C OS=Homo sapiens OX=9606 GN=UBE2C PE=1 SV=1 5.83 3430.2 - 539918 - - - 1.4237 - 1.813 0.121 - 150.2 1 1 0 0.0013 7 0 0 0 1.55E+07 9.67E+06 - - - 1.8195 0.908 230117_WJC_METTL3_WT_vs_EV_F05.17234.17234.2 6.74 14-Jun R.LFPGLAIK[136.11].L "sp|Q99661|KIF2C_HUMAN,tr|Q5JR91|Q5JR91_HUMAN" 2 865.5517 3.33 40826 17234 2 865.552397 433.7831 Kinesin-like protein KIF2C OS=Homo sapiens OX=9606 GN=KIF2C PE=1 SV=2 8.75 3430.3 - 784880 - - - 0.8342 - 0.926 0.031 - 74 1 2 0 0.0007 8 0 0 0 1.20E+08 3.61E+07 - - - -0.9621 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.17236.17236.2 0.104 18-Oct K.VALAVSLNLR.T "sp|Q03426|KIME_HUMAN,tr|F5GXC0|F5GXC0_HUMAN,tr|F5H163|F5H163_HUMAN,tr|F5H092|F5H092_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|F5H368|F5H368_HUMAN,tr|A0A1W2PS16|A0A1W2PS16_HUMAN" 7 1054.6499 1.36 40828 17236 2 1054.653717 528.3322 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 9.72 3430.5 - 328072 - - - 3.6391 - 1.981 0.137 - 254.4 1 2 0 0.0038 10 0 0 0 6.89E+06 5.06E+06 - - - 1.9598 0.9129 230117_WJC_METTL3_WT_vs_EV_F05.17239.17239.2 0.0107 14-Jul V.VGDIAQVK[136.11].Y "sp|Q01814|AT2B2_HUMAN,sp|P20020|AT2B1_HUMAN,sp|Q16720|AT2B3_HUMAN,sp|P23634|AT2B4_HUMAN,tr|A0A804HKZ0|A0A804HKZ0_HUMAN,tr|A0A2U3TZI3|A0A2U3TZI3_HUMAN,tr|A0A2U3U055|A0A2U3U055_HUMAN" 7 836.4847 1.3 40829 17239 2 836.484814 419.2496 Plasma membrane calcium-transporting ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2B2 PE=1 SV=2 5.81 3430.9 - 1.43E+06 - - - 0.1148 - 1.506 0.307 - 126.3 1 1 0 0.0001 8 0 0 0 1.72E+07 1.33E+07 - - - 2.5434 0.9949 230117_WJC_METTL3_WT_vs_EV_F05.17245.17245.2 0.22 14-Jun K.AITAATLK.F sp|P11277|SPTB1_HUMAN 1 787.4804 0.75 40835 17245 2 787.482125 394.7475 "Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB PE=1 SV=5" 8.8 3431.5 - 781310 - - - 2.2489 - 1.352 0.157 - 128.2 1 2 0 0.0018 8 0 0 0 9.86E+06 1.32E+07 - - - 1.1096 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.17246.17246.2 0.0725 20-Aug K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.2 40836 17246 2 1235.762186 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3431.6 - 723788 - - - 1.6411 - 1.619 0.321 - 197.5 1 2 0 0.002 11 0 0 0 1.09E+07 9.04E+06 - - - 2.7147 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17250.17250.2 0.0732 14-Oct K.IDLTLLNR.L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 956.5655 1.16 40838 17250 2 956.5655 479.29 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.84 3432.2 - 1.31E+06 - - - 0.0199 - 2.197 0.325 - 317.9 1 2 0 0 8 0 0 0 1.14E+08 9.79E+07 - - - 3.8153 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17251.17251.2 0.643 14-Sep K.IDLTLLNR[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 966.5738 1.16 40839 17251 2 966.574687 484.2942 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.84 3432.2 - 1.20E+06 - - - 0.9684 - 2.013 0.331 - 254.6 1 2 0 0.0009 8 0 0 0 1.14E+08 9.80E+07 - - - 3.5955 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.17252.17252.2 0.266 12-Aug K.TYDLLFK.L sp|P61026|RAB10_HUMAN 1 898.48 0.7 40840 17252 2 898.48053 450.2473 Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1 5.5 3432.3 - 765910 - - - 0.5676 - 1.529 0.259 - 265.2 1 2 0 0.0005 7 0 0 0 2.32E+07 3.32E+07 - - - 2.2992 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17254.17254.2 0.0375 18-Nov R.FSNLLGTVYR[166.11].R "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN,tr|C9J544|C9J544_HUMAN" 3 1178.6323 1.06 40842 17254 2 1178.634865 590.3234 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 8.75 3432.5 - 602323 - - - 2.1525 - 2.198 0.317 - 428.2 1 2 0 0.0025 10 0 0 0 1.71E+07 1.61E+07 - - - 3.5799 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17258.17258.2 0.00273 16-Sep R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 0.94 40844 17258 2 997.607573 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3433 - 3.49E+06 - - - 2.4118 - 2.085 0.427 - 218.1 1 2 0 0.0024 9 0 0 0 3.50E+09 3.71E+09 - - - 4.3198 0.999 230117_WJC_METTL3_WT_vs_EV_F05.17259.17259.2 0.0242 14-Aug K.FYFEELGK[136.11].Y sp|Q10471|GALT2_HUMAN 1 1039.5106 1.14 40845 17259 2 1039.512568 520.7626 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3433.1 - 767329 - - - 1.8951 - 1.207 0.392 - 156.5 1 2 0 0.002 8 0 0 0 4.54E+07 4.00E+07 - - - 2.5031 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17262.17262.2 0.000534 28-Sep R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 6.37 40848 17262 2 1494.919368 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3433.4 - 94667.5 - - - 2.1493 - 1.881 0.413 - 185.7 1 2 0 0.0032 15 0 0 0 4.18E+07 6.56E+06 - - - 3.6437 0.997 230117_WJC_METTL3_WT_vs_EV_F05.17268.17268.2 7.24E-06 22-Aug R.LNVGGTYFLTTR[166.11].Q "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1350.7171 0.74 40852 17268 2 1350.724536 676.3658 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3434 - 408362 - - - 5.4897 - 2.073 0.424 - 198.3 1 2 0 0.0074 12 0 0 0 1.23E+07 1.65E+07 - - - 4.0885 0.9012 230117_WJC_METTL3_WT_vs_EV_F05.17269.17269.2 3.92 14-May K.LFAELEIK.R "sp|O75937|DNJC8_HUMAN,tr|S4R3J5|S4R3J5_HUMAN" 2 961.5484 1.56 40853 17269 2 961.547707 481.7815 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.53 3434.1 - 312366 - - - -0.7561 - 1.018 0.051 - 43.5 1 2 0 -0.0007 8 0 0 0 8.87E+06 5.70E+06 - - - -0.5287 1 230117_WJC_METTL3_WT_vs_EV_F05.17270.17270.2 4.96E-05 15/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 8.09 40854 17270 2 1484.910819 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3434.3 - 302532 - - - 1.9759 - 2.496 0.563 - 601 1 2 0 0.0029 15 0 0 0 7.00E+07 8.65E+06 - - - 5.4472 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17273.17273.2 0.0011 18-Sep R.LLFNDVQTLK[136.11].D "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1197.6849 1.03 40855 17273 2 1197.687815 599.8497 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.84 3434.7 - 1.41E+06 - - - 2.4556 - 1.781 0.339 - 208.3 1 2 0 0.0029 10 0 0 0 3.03E+07 2.95E+07 - - - 3.155 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17274.17274.2 0.0263 18-Sep R.LLFNDVQTLK.D "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1189.6707 1.03 40856 17274 2 1189.673537 595.8426 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.84 3434.7 - 1.10E+06 - - - 2.4065 - 1.975 0.393 - 198.4 1 2 0 0.0029 10 0 0 0 3.03E+07 2.95E+07 - - - 3.8425 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17275.17275.2 0.0172 18-Sep R.FSNLLGTVYR.R "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN,tr|C9J544|C9J544_HUMAN" 3 1168.6241 1.06 40857 17275 2 1168.625403 585.3193 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 8.75 3434.8 - 986784 - - - 1.1509 - 1.419 0.38 - 236.9 1 2 0 0.0013 10 0 0 0 1.71E+07 1.61E+07 - - - 2.8241 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.17276.17276.2 4.42E-05 20-Oct R.FLPEFAGTQLK.L sp|Q9UBZ4|APEX2_HUMAN 1 1249.6707 1.27 40858 17276 2 1249.674535 625.8426 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 6 3434.9 - 888972 - - - 3.0896 - 1.77 0.362 - 362.7 1 2 0 0.0039 11 0 0 0 6.73E+07 5.30E+07 - - - 3.2582 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.17277.17277.2 0.00174 20-Sep R.FLPEFAGTQLK[136.11].L sp|Q9UBZ4|APEX2_HUMAN 1 1257.6849 1.27 40859 17277 2 1257.683709 629.8497 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 6 3435 - 640547 - - - -0.9263 - 1.565 0.355 - 243.3 1 2 0 -0.0012 11 0 0 0 6.76E+07 5.30E+07 - - - 2.8743 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.17281.17281.2 0.0132 14-Aug K.DIVYIGLR.D "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN" 2 947.544 999 40861 17281 2 947.545971 474.7793 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 5.84 3435.6 - 1.22E+06 - - - 2.0622 - 1.709 0.326 - 273.1 1 2 0 0.002 8 0 0 0 2.89E+07 0.00E+00 - - - 3.0645 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.17282.17282.2 0.0299 14-Jul K.FYFEELGK.Y sp|Q10471|GALT2_HUMAN 1 1031.4964 1.16 40862 17282 2 1031.498472 516.7555 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3435.6 - 1.50E+06 - - - 2.0107 - 1.503 0.31 - 176 1 2 0 0.0021 8 0 0 0 4.63E+07 4.00E+07 - - - 2.5589 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17291.17291.2 0.00294 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 7005.31 40870 17291 2 1006.572213 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3436.6 - 1.26E+07 - - - 2.2999 - 1.934 0.48 - 248.8 1 2 0 0.0023 9 0 0 0 1.79E+11 2.56E+07 - - - 4.4938 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17292.17292.2 0.0167 16-Oct K.VVLPC[160.03]NLLR[166.11].M "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1092.6353 1.04 40871 17292 2 1092.636037 547.3249 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 8.22 3436.7 - 2.69E+06 - - - 0.669 - 1.512 0.418 - 431.8 1 2 0 0.0007 9 0 0 0 8.06E+07 7.78E+07 - - - 3.3242 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17293.17293.2 0.102 18-Oct K.IYVISLAEPR.L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1159.6601 1.29 40872 17293 2 1159.662259 580.8373 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3436.8 - 1.66E+06 - - - 1.8531 - 2.248 0.423 - 430.3 1 2 0 0.0022 10 0 0 0 1.36E+08 1.05E+08 - - - 4.4257 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17297.17297.2 0.000225 22-Aug R.LNVGGTYFLTTR.Q "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1340.7089 0.49 40876 17297 2 1340.710975 671.3617 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3437.4 - 593257 - - - 1.5842 - 2.064 0.454 - 189.8 1 2 0 0.0021 12 0 0 0 8.04E+06 1.63E+07 - - - 4.3002 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.17298.17298.3 0.000128 13/44 R.IIPVLLEHGLER.L "sp|P18858|DNLI1_HUMAN,tr|F5GZ28|F5GZ28_HUMAN,tr|M0R0Q7|M0R0Q7_HUMAN" 3 1387.8187 2.23 40877 17298 3 1387.822634 463.6135 DNA ligase 1 OS=Homo sapiens OX=9606 GN=LIG1 PE=1 SV=1 5.4 3437.5 - 525386 - - - 2.8087 - 2.445 0.43 - 218.1 1 2 0 0.0039 12 0 0 0 4.79E+06 2.15E+06 - - - 5.8112 0.9881 230117_WJC_METTL3_WT_vs_EV_F05.17304.17304.2 0.134 12-Jun K.LLLDMYR.S "sp|Q5VTR2|BRE1A_HUMAN,sp|O60308|CE104_HUMAN,tr|A0A6Q8PH38|A0A6Q8PH38_HUMAN,tr|A0A6Q8PHR0|A0A6Q8PHR0_HUMAN,tr|A0A6Q8PGF0|A0A6Q8PGF0_HUMAN,tr|J3QLL3|J3QLL3_HUMAN,tr|A0A6Q8PH69|A0A6Q8PH69_HUMAN,tr|A0A6Q8PHE1|A0A6Q8PHE1_HUMAN,tr|Q5SR27|Q5SR27_HUMAN,tr|A0A6Q8PGB3|A0A6Q8PGB3_HUMAN,tr|A0A6Q8PFR4|A0A6Q8PFR4_HUMAN" 11 922.4946 2.08 40881 17304 2 922.498064 462.2546 E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2 5.84 3438.3 - 644126 - - - 3.729 - 1.275 0.178 - 93.7 1 2 0 0.0034 7 0 0 0 1.84E+07 8.83E+06 - - - 1.1244 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17305.17305.2 1.48E-05 18-Oct R.AAGVVLEMIR.E "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN,tr|M0QXI6|M0QXI6_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 4 1057.5954 1.15 40882 17305 2 1057.597205 529.805 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6.05 3438.4 - 623638 - - - 1.7058 - 2.302 0.345 - 314 1 2 0 0.0018 10 0 0 0 4.26E+07 3.70E+07 - - - 3.9159 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.17309.17309.2 0.00284 16-Oct R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.94 40885 17309 2 989.595693 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3438.9 - 2.38E+08 - - - 4.7757 - 2.167 0.438 - 306.8 1 2 0 0.0047 9 0 0 0 3.50E+09 3.71E+09 - - - 4.5119 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.17315.17315.2 0.0409 18-Jul K.IYVISLAEPR[166.11].L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1169.6684 1.29 40890 17315 2 1169.669717 585.8415 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3439.6 - 3.18E+06 - - - 1.1431 - 1.915 0.261 - 163 2 2 0 0.0013 10 0 0 0 1.36E+08 1.05E+08 - - - 2.6474 0.9905 230117_WJC_METTL3_WT_vs_EV_F05.17321.17321.2 0.659 12-May K.FIDPFC[160.03]R[166.11].L sp|P56182|RRP1_HUMAN 1 963.4512 1.18 40895 17321 2 963.45137 482.7329 Ribosomal RNA processing protein 1 homolog A OS=Homo sapiens OX=9606 GN=RRP1 PE=1 SV=1 5.83 3440.1 - 1.28E+06 - - - 0.1837 - 1.147 0.226 - 41.1 9 2 0 0.0002 7 0 0 0 1.41E+07 1.19E+07 - - - 0.7185 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17334.17334.2 0.000896 18-Oct R.VVLPIEAPIR.M sp|P00403|COX2_HUMAN 1 1105.6859 1.51 40905 17334 2 1105.686595 553.8502 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 5.97 3441.7 - 1.49E+07 - - - 0.6014 - 1.719 0.448 - 378.6 1 2 0 0.0007 10 0 0 0 5.72E+08 3.78E+08 - - - 3.8619 0.9969 230117_WJC_METTL3_WT_vs_EV_F05.17340.17340.2 0.0732 18-Sep K.FLALEGNPLR[166.11].T sp|Q9H9A6|LRC40_HUMAN 1 1138.6374 4.14 40909 17340 2 1138.641871 570.326 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 6 3442.3 - 1.22E+06 - - - 3.9143 - 1.6 0.286 - 218.6 1 2 0 0.0045 10 0 0 0 1.30E+08 3.15E+07 - - - 2.4639 0.9015 230117_WJC_METTL3_WT_vs_EV_F05.17342.17342.2 0.000283 16-Nov R.PLVALLDGR.D "sp|P56545|CTBP2_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|E7ESU7|E7ESU7_HUMAN,tr|E7EUB3|E7EUB3_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|E7EPF8|E7EPF8_HUMAN,tr|E9PGB1|E9PGB1_HUMAN" 7 952.5706 1.6 40911 17342 2 952.568691 477.2926 C-terminal-binding protein 2 OS=Homo sapiens OX=9606 GN=CTBP2 PE=1 SV=1 6.27 3442.6 - 865137 - - - -1.9684 - 2.207 0.41 - 386.6 1 1 0 -0.0019 9 0 0 0 7.64E+07 4.77E+07 - - - 4.3589 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.17363.17363.2 0.396 14-Oct R.AYILNLVK.Q sp|P50991|TCPD_HUMAN 1 932.5695 7.44 40922 17363 2 932.569326 467.292 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.63 3445.2 - 1.66E+06 - - - -0.1909 - 1.781 0.346 - 343.4 1 2 0 -0.0002 8 0 0 0 2.16E+09 2.90E+08 - - - 3.3372 0.851 230117_WJC_METTL3_WT_vs_EV_F05.17370.17370.2 0.00395 14-Aug K.FDTPFLPK[136.11].P sp|Q14684|RRP1B_HUMAN 1 971.5208 1.37 40929 17370 2 971.519186 486.7677 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.84 3446.1 - 1.10E+06 - - - -1.6294 - 1.644 0.348 - 139 1 1 0 -0.0016 8 0 0 0 1.07E+08 7.80E+07 - - - 3.1102 1 230117_WJC_METTL3_WT_vs_EV_F05.17371.17371.2 1.85E-08 20-Dec R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 999 40930 17371 2 1201.606273 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3446.2 - 1.06E+06 - - - -2.3835 - 2.412 0.584 - 695.4 1 2 0 -0.0029 11 0 0 0 1.22E+07 0.00E+00 - - - 5.7354 0.999 230117_WJC_METTL3_WT_vs_EV_F05.17372.17372.2 0.257 14-Sep R.GIFEPFGK.L "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 893.4647 0.69 40931 17372 2 893.465688 447.7396 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 6 3446.4 - 881844 - - - 1.1013 - 1.439 0.306 - 252.6 1 2 0 0.001 8 0 0 0 9.41E+07 1.36E+08 - - - 2.3985 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17377.17377.2 0.000331 13/20 R.MGPGIGAILER[166.11].S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1122.6095 2.59 40933 17377 2 1122.609187 562.312 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.75 3446.9 - 2.25E+06 - - - -0.2646 - 2.211 0.438 - 557.4 1 2 0 -0.0003 11 0 0 0 1.59E+08 6.14E+07 - - - 4.4224 0.9075 230117_WJC_METTL3_WT_vs_EV_F05.17382.17382.2 0.0935 12-Jun K.ELEFYLR[166.11].K "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 978.505 0.93 40937 17382 2 978.500564 490.2598 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.53 3447.4 - 3.42E+06 - - - -4.5365 - 1.201 0.206 - 206 1 2 0 -0.0044 7 0 0 0 2.81E+08 3.02E+08 - - - 1.1415 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.17387.17387.2 0.0753 16-Nov K.IAFAITAIK.G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 946.5852 1.17 40938 17387 2 946.58862 474.2999 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3448.1 - 468709 - - - 3.6616 - 2.4 0.349 - 305.7 1 2 0 0.0035 9 0 0 0 4.11E+09 3.51E+09 - - - 4.1504 0.9951 230117_WJC_METTL3_WT_vs_EV_F05.17389.17389.2 0.291 16-Aug K.IFTQLEEFR[166.11].A sp|O60306|AQR_HUMAN 1 1191.6163 0.8 40940 17389 2 1191.613458 596.8154 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 4.53 3448.4 - 639685 - - - -2.4219 - 1.675 0.299 - 233.1 1 2 0 -0.0029 9 0 0 0 1.32E+07 1.65E+07 - - - 2.7408 0.9607 230117_WJC_METTL3_WT_vs_EV_F05.17397.17397.2 0.166 14-Jul R.FLDDLGLK.F sp|Q14126|DSG2_HUMAN 1 919.5015 1.52 40943 17397 2 919.498207 460.758 Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2 4.21 3449.5 - 5.51E+06 - - - -3.5639 - 1.379 0.186 - 110.3 1 2 0 -0.0033 8 0 0 0 3.47E+07 2.29E+07 - - - 1.383 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17399.17399.2 0.217 16-Oct K.IAFAITAIK[136.11].G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 954.5994 1.17 40945 17399 2 954.601138 478.307 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3449.6 - 1.13E+07 - - - 1.8688 - 2.234 0.264 - 237.5 1 2 0 0.0018 9 0 0 0 4.11E+09 3.51E+09 - - - 3.3158 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.17401.17401.2 0.0174 18-Aug R.LGLPGEVFGR.S sp|O95409|ZIC2_HUMAN 1 1043.5764 2.33 40947 17401 2 1043.576632 522.7955 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 6 3449.8 - 4.72E+06 - - - 0.2415 - 1.531 0.308 - 128.6 1 2 0 0.0003 10 0 0 0 2.57E+08 1.10E+08 - - - 2.5047 0.9897 230117_WJC_METTL3_WT_vs_EV_F05.17415.17415.2 0.0285 14-Jul R.FLDDLGLK[136.11].F sp|Q14126|DSG2_HUMAN 1 927.5157 1.52 40956 17415 2 927.511745 464.7651 Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2 4.21 3451.6 - 1.59E+06 - - - -4.2468 - 1.44 0.42 - 125.2 1 2 0 -0.0039 8 0 0 0 3.47E+07 2.29E+07 - - - 3.2416 0.919 230117_WJC_METTL3_WT_vs_EV_F05.17416.17416.2 0.0942 16-Aug K.YPQLLPGIR[166.11].G sp|P23526|SAHH_HUMAN 1 1065.621 0.99 40957 17416 2 1065.614478 533.8178 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 8.75 3451.8 - 1.55E+06 - - - -6.1532 - 1.446 0.275 - 175.4 1 2 0 -0.0066 9 0 0 0 3.38E+07 3.42E+07 - - - 2.1371 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17438.17438.2 0.0245 18-Oct R.LAGLSAALLR.T "sp|P51649|SSDH_HUMAN,tr|A0A5F9ZH98|A0A5F9ZH98_HUMAN,tr|C9J8Q5|C9J8Q5_HUMAN" 3 983.6128 0.82 40967 17438 2 983.615002 492.8137 "Succinate-semialdehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH5A1 PE=1 SV=2" 9.75 3454.4 - 259788 - - - 2.2743 - 2.073 0.32 - 239.6 1 2 0 0.0022 10 0 0 0 2.24E+07 2.73E+07 - - - 3.4387 0.9907 230117_WJC_METTL3_WT_vs_EV_F05.17441.17441.2 0.035 16-Oct K.SALLALGLK.C sp|Q12874|SF3A3_HUMAN 1 884.5695 3.29 40968 17441 2 884.566446 443.292 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3454.8 - 1.16E+06 - - - -3.457 - 1.919 0.245 - 353.5 1 2 0 -0.0031 9 0 0 0 2.19E+08 6.67E+07 - - - 2.7353 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17442.17442.2 0.00263 16-Sep K.ALQFLEEVK.V sp|P40227|TCPZ_HUMAN 1 1075.5914 999 40969 17442 2 1075.591789 538.803 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 3455 - 1.05E+06 - - - 0.3979 - 1.842 0.301 - 260.7 1 2 0 0.0004 9 0 0 0 5.27E+07 0.00E+00 - - - 3.0313 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17443.17443.2 0.00449 13/20 R.ALTALGLAVPR.G sp|Q9BVQ7|SPA5L_HUMAN 1 1080.6655 5.81 40970 17443 2 1080.664553 541.34 Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2 9.79 3455.1 - 1.01E+06 - - - -0.9031 - 2.622 0.359 - 599.2 1 2 0 -0.001 11 0 0 0 2.81E+07 4.83E+06 - - - 4.2999 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17444.17444.2 3.17E-05 18-Oct R.FQSLGVAFYR.G "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1186.6135 1.76 40971 17444 2 1186.616484 594.314 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 8.75 3455.2 - 787306 - - - 2.5198 - 1.99 0.428 - 288.7 1 2 0 0.003 10 0 0 0 5.60E+07 3.18E+07 - - - 4.1221 0.9545 230117_WJC_METTL3_WT_vs_EV_F05.17449.17449.2 1.51 14-Jul K.GLGILSLK[136.11].Q sp|Q92616|GCN1_HUMAN 1 807.5309 0.82 40974 17449 2 807.528132 404.7727 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.75 3455.9 - 1.43E+06 - - - -3.4773 - 1.367 0.167 - 147.1 1 2 0 -0.0028 8 0 0 0 3.13E+07 3.81E+07 - - - 1.2164 0.9952 230117_WJC_METTL3_WT_vs_EV_F05.17450.17450.2 0.0529 16-Sep K.SALLALGLK[136.11].C sp|Q12874|SF3A3_HUMAN 1 892.5837 3.31 40975 17450 2 892.588477 447.2991 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3456 - 1.96E+06 - - - 5.3474 - 1.962 0.286 - 264.7 1 2 0 0.0048 9 0 0 0 2.19E+08 6.63E+07 - - - 3.1017 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17451.17451.2 0.00866 20-Oct R.ALTALGLAVPR[166.11].G sp|Q9BVQ7|SPA5L_HUMAN 1 1090.6738 5.81 40976 17451 2 1090.674636 546.3442 Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2 9.79 3456.2 - 992948 - - - 0.7674 - 2.112 0.332 - 246.4 1 2 0 0.0008 11 0 0 0 2.81E+07 4.83E+06 - - - 3.5154 0.999 230117_WJC_METTL3_WT_vs_EV_F05.17458.17458.2 5.30E-05 18-Nov R.FQSLGVAFYR[166.11].G "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1196.6218 1.74 40978 17458 2 1196.626724 599.3182 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 8.75 3457.1 - 1.52E+06 - - - 4.145 - 2.12 0.441 - 362.1 1 2 0 0.005 10 0 0 0 5.54E+07 3.18E+07 - - - 4.3941 0.9957 230117_WJC_METTL3_WT_vs_EV_F05.17463.17463.2 0.00281 14-Sep K.IIDFGLAR.R "sp|Q86YV6|MYLK4_HUMAN,sp|Q32MK0|MYLK3_HUMAN,sp|Q9H1R3|MYLK2_HUMAN,sp|P53778|MK12_HUMAN,sp|O15264|MK13_HUMAN,sp|P45983|MK08_HUMAN,sp|Q16539|MK14_HUMAN,sp|P45984|MK09_HUMAN,sp|Q15759|MK11_HUMAN,sp|P53779|MK10_HUMAN,sp|Q15746|MYLK_HUMAN,tr|A0A286YFD7|A0A286YFD7_HUMAN,tr|A0A286YES0|A0A286YES0_HUMAN,tr|A0A286YEQ0|A0A286YEQ0_HUMAN,tr|A0A286YEX7|A0A286YEX7_HUMAN,tr|A0A286YFC0|A0A286YFC0_HUMAN,tr|B5MDL5|B5MDL5_HUMAN,tr|A0A286YES9|A0A286YES9_HUMAN,tr|A0A286YF97|A0A286YF97_HUMAN,tr|D6RCB1|D6RCB1_HUMAN,tr|A0A286YF19|A0A286YF19_HUMAN,tr|A0A286YFN2|A0A286YFN2_HUMAN,tr|D6RJF9|D6RJF9_HUMAN,tr|A0A286YEY0|A0A286YEY0_HUMAN,tr|Q5R3E6|Q5R3E6_HUMAN,tr|A0A286YEV8|A0A286YEV8_HUMAN,tr|B4E0K5|B4E0K5_HUMAN,tr|A0A286YF85|A0A286YF85_HUMAN,tr|A0A286YFI3|A0A286YFI3_HUMAN,tr|F8W9R5|F8W9R5_HUMAN,tr|A0A2R8Y4U5|A0A2R8Y4U5_HUMAN,tr|A0A286YFM6|A0A286YFM6_HUMAN,tr|A0A286YEV3|A0A286YEV3_HUMAN,tr|A0A286YF83|A0A286YF83_HUMAN,tr|A0A286YFJ6|A0A286YFJ6_HUMAN,tr|A0A286YF62|A0A286YF62_HUMAN,tr|A0A286YF02|A0A286YF02_HUMAN,tr|J3KNK1|J3KNK1_HUMAN,tr|A0A286YEQ7|A0A286YEQ7_HUMAN,tr|A0A286YFJ4|A0A286YFJ4_HUMAN,tr|A0A1W2PPZ3|A0A1W2PPZ3_HUMAN,tr|A0A286YEN5|A0A286YEN5_HUMAN,tr|A0A286YFA6|A0A286YFA6_HUMAN,tr|A0A1P0B7D2|A0A1P0B7D2_HUMAN,tr|A0A1W2PRF2|A0A1W2PRF2_HUMAN,tr|D7R525|D7R525_HUMAN,tr|A0A286YF35|A0A286YF35_HUMAN,tr|A0A286YFB6|A0A286YFB6_HUMAN,tr|A0A286YFE2|A0A286YFE2_HUMAN,tr|A0A286YEW9|A0A286YEW9_HUMAN,tr|E7EX54|E7EX54_HUMAN" 51 903.5178 2.91 40981 17463 2 903.520469 452.7662 Myosin light chain kinase family member 4 OS=Homo sapiens OX=9606 GN=MYLK4 PE=1 SV=2 5.84 3457.8 - 480459 - - - 2.9518 - 1.935 0.07 - 217.5 1 2 0 0.0027 8 0 0 0 2.96E+07 1.02E+07 - - - 1.548 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.17464.17464.2 0.0018 20-Sep K.FSPAGPILSIR.L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1156.6604 1.03 40982 17464 2 1156.661694 579.3375 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3457.9 - 819501 - - - 1.0807 - 1.65 0.246 - 265.3 1 2 0 0.0013 11 0 0 0 4.45E+08 4.33E+08 - - - 2.2123 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17469.17469.2 0.000196 20-Nov K.FSPAGPILSIR[166.11].L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1166.6687 1.03 40983 17469 2 1166.670706 584.3416 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3458.6 - 610558 - - - 1.7074 - 2.038 0.381 - 478 1 2 0 0.002 11 0 0 0 4.46E+08 4.33E+08 - - - 3.7805 1 230117_WJC_METTL3_WT_vs_EV_F05.17475.17475.2 0.000292 18-Dec D.TLDNDIMLIK.L "sp|P35030|TRY3_HUMAN,tr|A0A7P0MNE9|A0A7P0MNE9_HUMAN" 2 1174.6268 26.5 40985 17475 2 1174.627223 588.3207 Trypsin-3 OS=Homo sapiens OX=9606 GN=PRSS3 PE=1 SV=2 4.21 3459.5 - 1.85E+06 - - - 0.3933 - 2.047 0.493 - 291.8 1 1 0 0.0005 10 0 0 0 7.21E+07 2.72E+06 - - - 4.6818 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.17478.17478.2 0.0121 20-Nov K.VLADLAIYEPK[136.11].T sp|Q9BYC9|RM20_HUMAN 1 1238.7002 0.99 40988 17478 2 1238.703109 620.3574 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3459.9 - 429986 - - - 2.3565 - 1.891 0.24 - 274.8 1 2 0 0.0029 11 0 0 0 1.32E+07 1.33E+07 - - - 2.5362 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.17482.17482.2 0.00436 14-Sep R.GPIAFWAR[166.11].R "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H909|Q5H909_HUMAN" 2 926.5002 1.25 40990 17482 2 926.502603 464.2574 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 9.75 3460.5 - 423969 - - - 2.6023 - 1.651 0.338 - 282.8 1 2 0 0.0024 8 0 0 0 2.29E+07 1.83E+07 - - - 3.0489 0.9632 230117_WJC_METTL3_WT_vs_EV_F05.17491.17491.2 0.00015 26-Oct R.GLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1541.7726 - 40995 17491 2 1541.772351 771.8936 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3461.6 - 697279 - - - -0.144 - 2.017 0.448 - 97 1 1 0 -0.0002 14 0 0 0 - - - - - 4.1105 0.9937 230117_WJC_METTL3_WT_vs_EV_F05.17492.17492.2 0.0107 14-Jul R.GLFIIDGK.G sp|P32119|PRDX2_HUMAN 1 861.496 2.4 40996 17492 2 861.493683 431.7553 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3461.7 - 692668 - - - -2.6942 - 1.469 0.331 - 195.6 1 2 0 -0.0023 8 0 0 0 2.48E+08 1.04E+08 - - - 2.6449 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.17496.17496.2 0.00207 14-Jul R.GLFIIDGK[136.11].G sp|P32119|PRDX2_HUMAN 1 869.5102 2.38 40998 17496 2 869.510149 435.7624 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3462.2 - 1.60E+06 - - - -0.0633 - 1.391 0.42 - 186.5 1 2 0 -0.0001 8 0 0 0 2.46E+08 1.04E+08 - - - 3.1384 1 230117_WJC_METTL3_WT_vs_EV_F05.17497.17497.2 1.35E-06 13/20 K.VYGAILVAVER.L sp|Q9Y6J9|TAF6L_HUMAN 1 1188.6867 0.8 40999 17497 2 1188.684124 595.3506 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 5.97 3462.4 - 893162 - - - -2.1326 - 2.504 0.548 - 569.7 1 2 0 -0.0025 11 0 0 0 1.93E+07 2.41E+07 - - - 5.5708 1 230117_WJC_METTL3_WT_vs_EV_F05.17499.17499.2 0.000133 14/20 K.LGNPIVPLNIR.L sp|P78527|PRKDC_HUMAN 1 1204.7292 1.02 41001 17499 2 1204.734099 603.3719 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3462.6 - 729068 - - - 4.0731 - 2.384 0.509 - 667.8 1 2 0 0.0049 11 0 0 0 9.92E+06 9.73E+06 - - - 5.1492 0.9942 230117_WJC_METTL3_WT_vs_EV_F05.17500.17500.2 1.06 12-Jul K.SLDIFIK.A sp|Q9H583|HEAT1_HUMAN 1 834.4851 0.54 41002 17500 2 834.487428 418.2498 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.55 3462.7 - 568124 - - - 2.7838 - 1.31 0.181 - 184.3 1 2 0 0.0023 7 0 0 0 8.81E+06 1.63E+07 - - - 1.2327 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.17501.17501.2 0.00188 18-Jun K.LLYPLQEVER[166.11].F "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 1268.7004 1.06 41003 17501 2 1268.70627 635.3575 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.53 3462.9 - 393862 - - - 4.6205 - 1.558 0.356 - 134.6 1 2 0 0.0059 10 0 0 0 5.55E+06 5.22E+06 - - - 2.9062 0.9895 230117_WJC_METTL3_WT_vs_EV_F05.17503.17503.2 1.96 12-May K.QFLLLSR.Q sp|Q5T447|HECD3_HUMAN 1 875.5229 1.62 41005 17503 2 875.52428 438.7687 E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens OX=9606 GN=HECTD3 PE=1 SV=1 9.75 3463.1 - 257667 - - - 1.5899 - 1.396 0.084 - 77.5 4 2 0 0.0014 7 0 0 0 5.67E+06 3.49E+06 - - - 0.4491 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17505.17505.2 0.00125 16-Sep R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 0.89 41006 17505 2 997.607899 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3463.3 - 784915 - - - 2.7386 - 2.162 0.296 - 205.2 1 2 0 0.0027 9 0 0 0 1.48E+08 1.66E+08 - - - 3.457 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.17510.17510.2 0.000576 18-Dec K.VGDQILLAIK.G sp|Q6P1L8|RM14_HUMAN 1 1068.6543 1.72 41009 17510 2 1068.65876 535.3344 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3463.9 - 506671 - - - 4.1772 - 2.199 0.423 - 471.2 1 2 0 0.0045 10 0 0 0 4.75E+07 2.76E+07 - - - 4.3634 0.9949 230117_WJC_METTL3_WT_vs_EV_F05.17512.17512.2 1.16 12-Jul K.ITWSIIR[166.11].E sp|P38606|VATA_HUMAN 1 897.5312 1.06 41011 17512 2 897.53364 449.7729 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 9.75 3464.2 - 580276 - - - 2.7654 - 1.492 0.138 - 140.2 1 2 0 0.0025 7 0 0 0 7.78E+06 7.32E+06 - - - 1.3273 1 230117_WJC_METTL3_WT_vs_EV_F05.17513.17513.2 3.68E-05 18-Dec K.VGDQILLAIK[136.11].G sp|Q6P1L8|RM14_HUMAN 1 1076.6685 1.72 41012 17513 2 1076.668107 539.3415 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3464.3 - 538611 - - - -0.3613 - 2.396 0.458 - 418.2 1 2 0 -0.0004 10 0 0 0 4.75E+07 2.76E+07 - - - 4.8627 1 230117_WJC_METTL3_WT_vs_EV_F05.17517.17517.2 1.57E-06 16/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 4.7 41015 17517 2 1484.91008 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3464.8 - 786661 - - - 1.4782 - 2.517 0.565 - 592.8 1 2 0 0.0022 15 0 0 0 4.63E+07 9.86E+06 - - - 5.4828 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.17519.17519.2 0.000413 13/20 K.VLADLAIYEPK.T sp|Q9BYC9|RM20_HUMAN 1 1230.686 0.99 41017 17519 2 1230.685272 616.3503 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3465 - 740233 - - - -0.5834 - 2.126 0.309 - 334.2 1 2 0 -0.0007 11 0 0 0 1.32E+07 1.33E+07 - - - 3.3635 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17521.17521.2 0.000589 18-Aug K.LLYPLQEVER.F "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 1258.6921 1.03 41018 17521 2 1258.694526 630.3533 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.53 3465.2 - 252848 - - - 1.8972 - 1.754 0.443 - 270.8 1 2 0 0.0024 10 0 0 0 5.55E+06 5.38E+06 - - - 3.8807 1 230117_WJC_METTL3_WT_vs_EV_F05.17522.17522.2 5.88E-06 20-Nov K.VYGAILVAVER[166.11].L sp|Q9Y6J9|TAF6L_HUMAN 1 1198.6949 0.8 41019 17522 2 1198.692237 600.3547 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 5.97 3465.4 - 360634 - - - -2.2458 - 2.31 0.565 - 431.9 1 2 0 -0.0027 11 0 0 0 1.92E+07 2.41E+07 - - - 5.4782 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17523.17523.2 0.00084 14-Sep R.GPIAFWAR.R "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H909|Q5H909_HUMAN" 2 916.4919 1.26 41020 17523 2 916.493307 459.2532 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 9.75 3465.5 - 2.11E+06 - - - 1.5112 - 1.707 0.36 - 423.3 1 2 0 0.0014 8 0 0 0 2.40E+07 1.90E+07 - - - 3.3123 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.17524.17524.2 0.00176 18-Oct R.IAEFAFEYAR.N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1215.5924 2.55 41021 17524 2 1215.593873 608.8035 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3465.6 - 765171 - - - 1.192 - 2.107 0.241 - 321.5 1 2 0 0.0014 10 0 0 0 1.88E+07 7.38E+06 - - - 2.9008 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.17525.17525.2 0.00526 14-Aug R.LLNVWQVR.S "sp|Q15061|WDR43_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 2 1026.5974 1.2 41022 17525 2 1026.597406 514.306 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 9.75 3465.7 - 718424 - - - -0.0429 - 1.652 0.349 - 212.7 1 2 0 0 8 0 0 0 3.38E+07 2.83E+07 - - - 3.1327 0.995 230117_WJC_METTL3_WT_vs_EV_F05.17534.17534.2 3.13 14-Aug R.NLLTGLVR[166.11].H "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 894.5526 1.19 41029 17534 2 894.553418 448.2836 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 9.75 3466.8 - 2.46E+06 - - - 0.8909 - 1.489 0.104 - 260.4 1 2 0 0.0008 8 0 0 0 8.45E+07 7.10E+07 - - - 1.0096 0.9896 230117_WJC_METTL3_WT_vs_EV_F05.17535.17535.2 0.0963 12-Jul R.IIFDDFR[166.11].E sp|P46977|STT3A_HUMAN 1 934.4788 1.18 41030 17535 2 934.478374 468.2467 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.21 3466.9 - 1.98E+06 - - - -0.443 - 1.133 0.199 - 123.3 1 2 0 -0.0004 7 0 0 0 6.61E+07 5.61E+07 - - - 0.9063 1 230117_WJC_METTL3_WT_vs_EV_F05.17536.17536.2 1.04E-06 18-Dec K.LGDDIDLIVR.C sp|O15371|EIF3D_HUMAN 1 1127.6186 1.06 41031 17536 2 1127.618074 564.8166 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3466.9 - 5.22E+06 - - - -0.5011 - 2.628 0.567 - 439.8 1 2 0 -0.0006 10 0 0 0 1.46E+08 1.37E+08 - - - 5.9257 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.17537.17537.2 1.48 13/18 K.ALLAEGVILR[166.11].R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1063.6629 1.39 41032 17537 2 1063.663679 532.8387 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3467.1 - 1.76E+06 - - - 0.7324 - 1.999 0.097 - 752.1 1 2 0 0.0008 10 0 0 0 1.57E+08 1.12E+08 - - - 1.6906 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17538.17538.2 0.0209 18-Oct K.ALLAEGVILR.R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1053.6546 1.39 41033 17538 2 1053.655916 527.8346 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3467.2 - 1.57E+06 - - - 1.2205 - 2.159 0.319 - 318 1 2 0 0.0013 10 0 0 0 1.57E+08 1.12E+08 - - - 3.545 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.17539.17539.2 0.0718 12-Jul R.LFLEFER[166.11].K "sp|O43663|PRC1_HUMAN,sp|Q96I25|SPF45_HUMAN,tr|H0YL53|H0YL53_HUMAN" 3 962.5101 0.71 41034 17539 2 962.511778 482.2623 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 3467.3 - 1.21E+06 - - - 1.7558 - 1.546 0.142 - 147.4 1 2 0 0.0017 7 0 0 0 1.16E+07 1.64E+07 - - - 1.4697 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.17540.17540.2 0.000346 18-Dec R.IAEFAFEYAR[166.11].N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1225.6007 2.55 41035 17540 2 1225.6047 613.8076 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3467.4 - 700596 - - - 3.2686 - 2.328 0.222 - 584.6 1 2 0 0.004 10 0 0 0 1.88E+07 7.38E+06 - - - 3.0381 1 230117_WJC_METTL3_WT_vs_EV_F05.17543.17543.2 0.000168 20-Nov R.LLYC[160.03]TTGVLLR.R "sp|Q6P158|DHX57_HUMAN,sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 3 1307.7271 0.8 41038 17543 2 1307.727006 654.8708 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 8.22 3467.8 - 299885 - - - -0.1055 - 2.213 0.499 - 511.5 1 2 0 -0.0001 11 0 0 0 5.13E+06 6.38E+06 - - - 4.8755 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17546.17546.2 0.00323 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 7005.31 41040 17546 2 1006.571471 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3468.2 - 7.71E+07 - - - 1.5627 - 1.929 0.477 - 261.1 1 2 0 0.0016 9 0 0 0 1.79E+11 2.56E+07 - - - 4.4644 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.17548.17548.2 0.658 14-Jul R.NLLTGLVR.H "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 884.5444 1.16 41041 17548 2 884.545633 443.2795 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 9.75 3468.4 - 1.07E+07 - - - 1.4493 - 1.324 0.187 - 210.5 1 2 0 0.0013 8 0 0 0 8.23E+07 7.10E+07 - - - 1.2682 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17550.17550.2 0.00309 14-Jul K.GFGFGLVK[136.11].L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 831.4734 1.21 41043 17550 2 831.473397 416.744 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3468.5 - 1.73E+06 - - - -0.0337 - 1.375 0.439 - 155.3 1 2 0 0 8 0 0 0 1.66E+08 1.38E+08 - - - 3.2439 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17551.17551.2 1.89E-05 14/22 K.TPAILYTYSGLR.N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1353.7293 2.25 41044 17551 2 1353.730247 677.8719 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3468.7 - 1.55E+06 - - - 0.735 - 2.941 0.331 - 836 1 2 0 0.001 12 0 0 0 8.15E+06 3.62E+06 - - - 4.3238 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.17553.17553.2 0.000899 20-Nov R.GILEGELEGIR.G "sp|O75600|KBL_HUMAN,tr|H7BZ75|H7BZ75_HUMAN,tr|F2Z340|F2Z340_HUMAN,tr|C9IZC9|C9IZC9_HUMAN" 4 1184.6401 4.72 41046 17553 2 1184.639367 593.3273 "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial OS=Homo sapiens OX=9606 GN=GCAT PE=1 SV=1" 4.25 3468.9 - 823484 - - - -0.6204 - 2.177 0.34 - 366.8 1 2 0 -0.0007 11 0 0 0 3.69E+06 7.82E+05 - - - 3.6565 1 230117_WJC_METTL3_WT_vs_EV_F05.17554.17554.2 1.90E-06 13/22 K.TPAILYTYSGLR[166.11].N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1363.7375 2.25 41047 17554 2 1363.740439 682.876 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3469.1 - 687924 - - - 2.139 - 2.924 0.383 - 683.4 1 2 0 0.0029 12 0 0 0 8.15E+06 3.62E+06 - - - 4.692 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.17557.17557.2 0.0449 16-Jul R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.89 41049 17557 2 989.59337 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3469.4 - 644567 - - - 2.4283 - 1.502 0.31 - 130.3 1 2 0 0.0024 9 0 0 0 1.48E+08 1.66E+08 - - - 2.5068 0.9762 230117_WJC_METTL3_WT_vs_EV_F05.17559.17559.2 3.67 14-Jun R.GIFPVLC[160.03]K[136.11].D "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 940.5296 1.85 41050 17559 2 940.529292 471.2721 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 8.22 3469.6 - 203916 - - - -0.2849 - 1.224 0.081 - 93 1 2 0 -0.0003 8 0 0 0 3.50E+07 1.90E+07 - - - 0.2488 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.17563.17563.2 0.184 16-Aug R.LNVLANVIR[166.11].K "sp|Q02218|ODO1_HUMAN,sp|Q9ULD0|OGDHL_HUMAN,tr|E9PFG7|E9PFG7_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|A0A0D9SFS3|A0A0D9SFS3_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 6 1020.6319 0.98 41054 17563 2 1020.634073 511.3232 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 9.75 3470.1 - 319052 - - - 2.0958 - 1.936 0.171 - 185.8 1 2 0 0.0021 9 0 0 0 9.08E+06 9.25E+06 - - - 2.2146 0.8966 230117_WJC_METTL3_WT_vs_EV_F05.17565.17565.2 0.997 14-Jul K.TTQLLFLK[136.11].A sp|O94874|UFL1_HUMAN 1 970.5943 2.87 41056 17565 2 970.599236 486.3044 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 8.41 3470.4 - 224015 - - - 5.1185 - 1.129 0.107 - 104.3 1 2 0 0.005 8 0 0 0 1.01E+07 3.52E+06 - - - 0.1957 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17566.17566.2 0.198 18-Sep R.LPLLAVC[160.03]DYK.Q "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1190.6369 0.62 41057 17566 2 1190.638344 596.3257 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.83 3470.5 - 215765 - - - 1.1859 - 2.122 0.313 - 251.4 1 2 0 0.0014 10 0 0 0 4.29E+06 6.87E+06 - - - 3.4524 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.17575.17575.2 0.377 14-Sep K.ISALALLK[136.11].M sp|Q92905|CSN5_HUMAN 1 835.5622 1.48 41064 17575 2 835.563679 418.7884 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 8.75 3471.7 - 702666 - - - 1.7222 - 1.789 0.19 - 171.7 1 2 0 0.0014 8 0 0 0 1.57E+07 1.06E+07 - - - 2.1981 1 230117_WJC_METTL3_WT_vs_EV_F05.17583.17583.2 3.41E-05 18-Nov K.LGDDIDLIVR[166.11].C sp|O15371|EIF3D_HUMAN 1 1137.6269 1.06 41071 17583 2 1137.629091 569.8207 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3472.7 - 9.80E+06 - - - 1.918 - 2.789 0.49 - 385 1 2 0 0.0022 10 0 0 0 1.46E+08 1.37E+08 - - - 5.5224 0.9939 230117_WJC_METTL3_WT_vs_EV_F05.17588.17588.2 0.418 16-Jul R.ILLLNEMEK.L "sp|P35573|GDE_HUMAN,tr|A0A1C7CYW1|A0A1C7CYW1_HUMAN" 2 1101.6104 1.44 41076 17588 2 1101.614504 551.8125 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 4.53 3473.1 - 644604 - - - 3.7418 - 1.504 0.199 - 105.9 1 2 0 0.0041 9 0 0 0 1.20E+07 8.37E+06 - - - 1.6903 0.999 230117_WJC_METTL3_WT_vs_EV_F05.17589.17589.2 0.00731 16-Aug R.YLGLLENVR[166.11].V "sp|O43795|MYO1B_HUMAN,sp|O94832|MYO1D_HUMAN,sp|Q9UBC5|MYO1A_HUMAN,sp|B0I1T2|MYO1G_HUMAN,tr|A0A3B3IU30|A0A3B3IU30_HUMAN,tr|G3V342|G3V342_HUMAN,tr|K7EIG7|K7EIG7_HUMAN,tr|E9PDF6|E9PDF6_HUMAN,tr|J3QRN6|J3QRN6_HUMAN" 9 1085.6109 1.89 41077 17589 2 1085.610701 543.8127 Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3 6 3473.3 - 323247 - - - -0.1511 - 1.577 0.343 - 184 1 2 0 -0.0002 9 0 0 0 1.69E+07 8.96E+06 - - - 2.8922 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17591.17591.2 0.00933 18-Aug K.ILETLYTLGK.A "sp|Q5W0V3|FHI2A_HUMAN,tr|Q5W0V4|Q5W0V4_HUMAN" 2 1149.6645 84.2 41079 17591 2 1149.666713 575.8395 FHF complex subunit HOOK interacting protein 2A OS=Homo sapiens OX=9606 GN=FHIP2A PE=1 SV=1 6 3473.5 - 267319 - - - 1.9023 - 1.722 0.305 - 116.8 1 2 0 0.0022 10 0 0 0 4.73E+06 5.61E+04 - - - 2.8101 1 230117_WJC_METTL3_WT_vs_EV_F05.17595.17595.2 3.87E-05 13/22 K.LPVGTTATLYFR[166.11].D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1347.7426 1.16 41081 17595 2 1347.74545 674.8786 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3474 - 547770 - - - 2.1095 - 2.167 0.513 - 396.5 1 2 0 0.0028 12 0 0 0 6.51E+06 5.61E+06 - - - 4.8639 1 230117_WJC_METTL3_WT_vs_EV_F05.17596.17596.2 2.01E-05 14/22 K.LPVGTTATLYFR.D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1337.7343 1.14 41082 17596 2 1337.73697 669.8744 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3474.2 - 413626 - - - 1.9683 - 2.457 0.51 - 725.4 1 2 0 0.0026 12 0 0 0 6.63E+06 5.79E+06 - - - 5.1723 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.17597.17597.2 0.00532 14-Aug K.GFGFGLVK.L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 823.4592 1.21 41083 17597 2 823.460009 412.7369 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3474.2 - 1.13E+07 - - - 0.9521 - 1.344 0.376 - 213.5 1 2 0 0.0008 8 0 0 0 1.66E+08 1.38E+08 - - - 2.7096 0.9907 230117_WJC_METTL3_WT_vs_EV_F05.17598.17598.2 0.761 14-Aug K.TILSLMTR[166.11].E sp|P53396|ACLY_HUMAN 1 943.54 1.07 41084 17598 2 943.542784 472.7773 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.41 3474.3 - 2.18E+06 - - - 2.9421 - 1.594 0.066 - 179.3 1 2 0 0.0028 8 0 0 0 2.65E+07 2.49E+07 - - - 0.9338 0.9951 230117_WJC_METTL3_WT_vs_EV_F05.17600.17600.2 0.678 16-Sep R.ILLLNEMEK[136.11].L "sp|P35573|GDE_HUMAN,tr|A0A1C7CYW1|A0A1C7CYW1_HUMAN" 2 1109.6246 1.63 41086 17600 2 1109.625101 555.8196 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 4.53 3474.5 - 789045 - - - 0.4677 - 1.764 0.059 - 172.1 1 2 0 0.0005 9 0 0 0 1.20E+07 7.38E+06 - - - 1.1187 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17603.17603.2 0.877 20-Dec K.SEIEYYAMLAK[136.11].T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1324.6464 1.04 41089 17603 2 1324.647849 663.3305 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3474.9 - 244215 - - - 1.0637 - 2.412 0.314 - 534.2 1 2 0 0.0014 11 0 0 0 6.59E+06 6.35E+06 - - - 3.7416 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.17604.17604.2 0.0084 22-Aug R.LPVPESITGFAR.L "sp|Q8N5K1|CISD2_HUMAN,tr|I3L1N9|I3L1N9_HUMAN,tr|A0A2R8Y540|A0A2R8Y540_HUMAN" 3 1285.703 0.18 41090 17604 2 1285.706588 643.8588 CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1 6 3475 - 186651 - - - 2.7619 - 1.505 0.178 - 191.9 1 2 0 0.0036 12 0 0 0 2.46E+06 1.37E+07 - - - 1.4302 0.9675 230117_WJC_METTL3_WT_vs_EV_F05.17607.17607.2 4.66 14-Jun K.TILSLMTR.E sp|P53396|ACLY_HUMAN 1 933.5317 1.05 41091 17607 2 933.535064 467.7731 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.41 3475.5 - 1.51E+06 - - - 3.5628 - 1.042 0.155 - 85.9 1 2 0 0.0033 8 0 0 0 2.65E+07 2.53E+07 - - - 0.3089 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.17608.17608.2 0.667 12-Jul K.FIGELFK.L "sp|O43432|IF4G3_HUMAN,sp|Q04637|IF4G1_HUMAN,tr|A0A804HJV5|A0A804HJV5_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|A0A0U1RQK7|A0A0U1RQK7_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|A0A0A0MSA7|A0A0A0MSA7_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 11 852.4745 0.33 41092 17608 2 852.475949 427.2445 Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2 6 3475.5 - 1.01E+06 - - - 1.6517 - 1.526 0.16 - 148.2 1 2 0 0.0014 7 0 0 0 4.94E+07 1.50E+08 - - - 1.5615 0.9943 230117_WJC_METTL3_WT_vs_EV_F05.17609.17609.2 0.892 12-Jul K.GVIFYLR.D "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 9 866.5014 4.17 41093 17609 2 866.503048 434.258 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 8.75 3475.6 - 713947 - - - 1.8742 - 1.447 0.097 - 188.6 1 2 0 0.0016 7 0 0 0 3.79E+07 9.08E+06 - - - 0.9277 0.943 230117_WJC_METTL3_WT_vs_EV_F05.17610.17610.2 0.713 12-Jun K.FIGELFK[136.11].L "sp|O43432|IF4G3_HUMAN,sp|Q04637|IF4G1_HUMAN,tr|A0A804HJV5|A0A804HJV5_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|A0A0U1RQK7|A0A0U1RQK7_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|A0A0A0MSA7|A0A0A0MSA7_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 11 860.4887 1.23 41094 17610 2 860.494119 431.2516 Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2 6 3475.7 - 654151 - - - 6.2499 - 1.286 0.186 - 84.8 1 2 0 0.0054 7 0 0 0 3.95E+07 3.21E+07 - - - 1.2101 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17611.17611.2 0.00216 16-Aug K.MIFDVESMK[136.11].K sp|P09874|PARP1_HUMAN 1 1106.5232 0.97 41095 17611 2 1106.523421 554.2689 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.37 3475.8 - 622119 - - - 0.2413 - 1.52 0.45 - 167.2 1 2 0 0.0003 9 0 0 0 8.74E+06 8.99E+06 - - - 3.576 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.17612.17612.2 0.000284 16-Oct R.LIDFLESGK.T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1020.5492 1.41 41096 17612 2 1020.548307 511.2819 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3475.9 - 416050 - - - -0.8378 - 1.903 0.419 - 243.3 1 2 0 -0.0009 9 0 0 0 9.44E+07 6.71E+07 - - - 3.9969 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17613.17613.2 0.0014 20-Oct K.SEIEYYAMLAK.T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1316.6322 0.97 41097 17613 2 1316.635124 659.3234 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3476 - 351034 - - - 2.1904 - 2.118 0.411 - 292.2 1 2 0 0.0029 11 0 0 0 6.81E+06 6.99E+06 - - - 4.1059 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.17616.17616.2 0.00297 18-Oct K.WSEALVLYDR[166.11].V sp|Q9UHB9|SRP68_HUMAN 1 1260.6378 1.83 41100 17616 2 1260.636525 631.3262 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.37 3476.4 - 222660 - - - -1.0177 - 2.111 0.392 - 372.3 1 2 0 -0.0013 10 0 0 0 3.76E+06 2.05E+06 - - - 4.0215 0.999 230117_WJC_METTL3_WT_vs_EV_F05.17620.17620.2 0.0135 16-Sep R.LIDFLESGK[136.11].T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1028.5634 1.41 41102 17620 2 1028.565917 515.289 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3476.9 - 4.27E+06 - - - 2.484 - 1.852 0.257 - 172.2 1 2 0 0.0026 9 0 0 0 9.44E+07 6.71E+07 - - - 2.7213 0.9946 230117_WJC_METTL3_WT_vs_EV_F05.17623.17623.2 0.223 16-Jun R.AVDVGAFLR[166.11].D "sp|Q96BT3|CENPT_HUMAN,tr|H3BUW2|H3BUW2_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 3 956.5319 0.92 41105 17623 2 956.533783 479.2732 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 5.88 3477.1 - 1.55E+06 - - - 1.9832 - 1.458 0.135 - 82.1 2 2 0 0.0019 9 0 0 0 1.91E+07 2.06E+07 - - - 0.9939 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.17624.17624.2 0.106 20-Oct R.ELLIIGGVAAR[166.11].D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1120.6844 1.19 41106 17624 2 1120.687451 561.3495 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3477.2 - 1.25E+06 - - - 2.7546 - 2.205 0.35 - 364.1 1 2 0 0.0031 11 0 0 0 2.19E+08 1.83E+08 - - - 3.7642 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17626.17626.2 0.0936 20-Nov R.ELLIIGGVAAR.D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1110.6761 1.17 41108 17626 2 1110.678971 556.3453 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3477.5 - 1.02E+06 - - - 2.5903 - 2.23 0.277 - 342.3 1 2 0 0.0029 11 0 0 0 2.19E+08 1.88E+08 - - - 3.2556 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17634.17634.2 2.56E-06 26-Aug K.NVGLDIEAEVPAVK.D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1452.7824 999 41116 17634 2 1452.784196 727.3985 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 3478.5 - 144394 - - - 1.2294 - 1.832 0.529 - 167 1 2 0 0.0018 14 0 0 0 3.55E+06 0.00E+00 - - - 4.4669 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17637.17637.2 0.0283 16-Nov R.LAVLPYELR.F "sp|Q9ULX3|NOB1_HUMAN,tr|H3BUR4|H3BUR4_HUMAN" 2 1072.6281 1.21 41117 17637 2 1072.63 537.3213 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 6 3478.9 - 6.21E+06 - - - 1.7891 - 2.149 0.224 - 615.6 1 2 0 0.0019 9 0 0 0 9.11E+07 7.54E+07 - - - 2.9081 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17638.17638.2 0.000341 16-Sep K.FPTLWSGAR[166.11].S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1043.5428 1.16 41118 17638 2 1043.544211 522.7787 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 9.75 3479 - 2.56E+06 - - - 1.3665 - 1.918 0.352 - 378.3 1 2 0 0.0014 9 0 0 0 7.45E+07 6.41E+07 - - - 3.5246 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.17639.17639.2 0.0299 16-Aug R.AVDVGAFLR.D "sp|Q96BT3|CENPT_HUMAN,tr|H3BUW2|H3BUW2_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 3 946.5236 0.92 41119 17639 2 946.526419 474.2691 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 5.88 3479.1 - 2.35E+06 - - - 2.9614 - 1.629 0.21 - 200.8 1 2 0 0.0028 9 0 0 0 1.91E+07 2.08E+07 - - - 2.0029 0.9768 230117_WJC_METTL3_WT_vs_EV_F05.17650.17650.2 3.74 14-May R.GIFPVLC[160.03]K.D "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 932.5154 1.73 41128 17650 2 932.515689 467.265 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 8.22 3480.4 - 1.26E+06 - - - 0.3528 - 1.007 0.133 - 64.3 1 2 0 0.0003 8 0 0 0 3.57E+07 2.06E+07 - - - 0.0443 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.17651.17651.2 4.46 14-Sep K.IYQVLDFR.L "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1052.5655 1.35 41129 17651 2 1052.568637 527.29 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 5.84 3480.5 - 849861 - - - 2.9984 - 1.927 0.192 - 295 1 2 0 0.0032 8 0 0 0 2.15E+07 1.59E+07 - - - 2.4365 0.9941 230117_WJC_METTL3_WT_vs_EV_F05.17652.17652.2 0.0294 14-Jul K.WLTLEVC[160.03]R.E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1075.5485 1.61 41130 17652 2 1075.547441 538.7815 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3480.6 - 3.88E+06 - - - -0.9391 - 1.33 0.232 - 206.2 1 2 0 -0.001 8 0 0 0 7.35E+07 4.56E+07 - - - 1.6143 0.9633 230117_WJC_METTL3_WT_vs_EV_F05.17659.17659.2 1.52 18-Jun K.SSLALGLELR.A sp|Q8TAP8|PPR35_HUMAN 1 1057.6132 1.99 41137 17659 2 1057.615735 529.8139 Protein phosphatase 1 regulatory subunit 35 OS=Homo sapiens OX=9606 GN=PPP1R35 PE=1 SV=1 5.72 3481.3 - 148883 - - - 2.4357 - 1.213 0.057 - 79.5 3 2 0 0.0026 10 0 0 0 3.16E+06 1.59E+06 - - - -0.2129 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.17664.17664.2 1.43 12-Jun R.ISPWLLR[166.11].V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 893.5362 0.32 41140 17664 2 893.53902 447.7754 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3481.9 - 716282 - - - 3.1079 - 1.445 0.231 - 146.8 1 2 0 0.0028 7 0 0 0 3.23E+07 1.02E+08 - - - 1.9127 0.9956 230117_WJC_METTL3_WT_vs_EV_F05.17674.17674.2 0.238 12-Aug R.ISPWLLR.V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 883.528 0.48 41148 17674 2 883.530238 442.7713 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3483 - 1.44E+06 - - - 2.5636 - 1.43 0.159 - 198 1 2 0 0.0023 7 0 0 0 2.97E+07 6.17E+07 - - - 1.348 0.9938 230117_WJC_METTL3_WT_vs_EV_F05.17675.17675.2 0.0332 14-Jun R.AFFSSYLK[136.11].S "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 969.5051 0.81 41149 17675 2 969.507834 485.7598 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.63 3483.2 - 549410 - - - 2.8004 - 1.083 0.257 - 87.2 1 2 0 0.0027 8 0 0 0 1.91E+07 2.36E+07 - - - 1.1788 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.17677.17677.2 0.0143 14-Jul R.AFFSSYLK.S "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 961.4909 0.81 41151 17677 2 961.492673 481.7527 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.63 3483.4 - 400900 - - - 1.8243 - 1.201 0.414 - 132.7 1 2 0 0.0018 8 0 0 0 1.91E+07 2.38E+07 - - - 2.6506 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17687.17687.2 0.000772 20-Oct R.YIVQVSPLGIR.L sp|Q10570|CPSF1_HUMAN 1 1243.7289 1.31 41159 17687 2 1243.731566 622.8717 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3484.6 - 2.41E+06 - - - 2.1773 - 1.988 0.437 - 379.3 1 2 0 0.0027 11 0 0 0 2.35E+07 1.79E+07 - - - 4.1267 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17688.17688.2 0.00426 16-Oct K.VNIIPIIAK.A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 979.643 1.1 41160 17688 2 979.64361 490.8288 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3484.8 - 3.26E+06 - - - 0.6196 - 1.87 0.349 - 364.7 1 2 0 0.0006 9 0 0 0 3.78E+07 3.44E+07 - - - 3.4294 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17689.17689.2 0.00287 14-Oct K.WLTLEVC[160.03]R[166.11].E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1085.5567 1.61 41161 17689 2 1085.55825 543.7856 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3484.8 - 5.59E+06 - - - 1.4085 - 1.916 0.392 - 584.6 1 2 0 0.0015 8 0 0 0 7.44E+07 4.63E+07 - - - 3.8969 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17690.17690.2 0.00195 16-Sep K.VNIIPIIAK[136.11].A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 987.6572 1.1 41162 17690 2 987.659491 494.8359 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3485 - 3.16E+06 - - - 2.3166 - 1.863 0.442 - 312.4 1 2 0 0.0023 9 0 0 0 3.78E+07 3.44E+07 - - - 4.1049 0.9901 230117_WJC_METTL3_WT_vs_EV_F05.17692.17692.2 0.0363 14-Sep R.IGLNLFNK.K "sp|Q6DN90|IQEC1_HUMAN,sp|Q5JU85|IQEC2_HUMAN,tr|A0A0C4DGT3|A0A0C4DGT3_HUMAN,tr|A0A1W2PRJ5|A0A1W2PRJ5_HUMAN,tr|A0A2R8Y7T6|A0A2R8Y7T6_HUMAN,tr|A0A6Q8PFR7|A0A6Q8PFR7_HUMAN,tr|A0A3B3IRZ4|A0A3B3IRZ4_HUMAN,tr|A0A2R8Y695|A0A2R8Y695_HUMAN,tr|A0A3B3IU98|A0A3B3IU98_HUMAN,tr|A0A1W2PR28|A0A1W2PR28_HUMAN" 10 917.5335 2.15 41164 17692 2 917.538598 459.774 IQ motif and SEC7 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=IQSEC1 PE=1 SV=1 8.75 3485.2 - 1.50E+06 - - - 5.6085 - 1.355 0.337 - 175.2 1 2 0 0.0051 8 0 0 0 1.52E+07 7.06E+06 - - - 2.4447 0.9615 230117_WJC_METTL3_WT_vs_EV_F05.17694.17694.2 0.334 14-Oct S.PLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 906.5526 1.32 41166 17694 2 906.554178 454.2836 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 10.18 3485.4 - 987409 - - - 1.7175 - 2.013 0.285 - 387.7 1 1 0 0.0016 8 0 0 0 6.07E+07 4.61E+07 - - - 3.2556 0.993 230117_WJC_METTL3_WT_vs_EV_F05.17698.17698.2 0.135 20-Aug K.ALGYFAVVTGK[136.11].G "sp|O60313|OPA1_HUMAN,tr|A0A2R8YD53|A0A2R8YD53_HUMAN,tr|C9JMB8|C9JMB8_HUMAN,tr|A0A2R8YDM2|A0A2R8YDM2_HUMAN,tr|E5KLJ9|E5KLJ9_HUMAN,tr|A0A2R8Y4Q3|A0A2R8Y4Q3_HUMAN,tr|A0A2R8Y3X5|A0A2R8Y3X5_HUMAN,tr|A0A2R8YGE5|A0A2R8YGE5_HUMAN,tr|A0A2R8YFD1|A0A2R8YFD1_HUMAN,tr|A0A2R8YE78|A0A2R8YE78_HUMAN" 10 1132.6372 1.39 41170 17698 2 1132.64075 567.3259 "Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3" 8.63 3485.9 - 427908 - - - 3.1378 - 1.491 0.153 - 92.1 1 2 0 0.0036 11 0 0 0 5.04E+06 3.63E+06 - - - 1.2505 1 230117_WJC_METTL3_WT_vs_EV_F05.17699.17699.2 7.21E-07 14/30 R.VINEPTAAALAYGLDK.S "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1644.8723 41.05 41171 17699 2 1644.874388 823.4434 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3486.1 - 392363 - - - 1.2773 - 2.812 0.53 - 484.4 1 2 0 0.0021 16 0 0 0 9.18E+06 2.24E+05 - - - 5.4968 1 230117_WJC_METTL3_WT_vs_EV_F05.17702.17702.2 5.64E-07 20-Dec R.IVLLDSSLEYK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1278.7071 10.88 41172 17702 2 1278.70917 640.3608 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3486.5 - 2.84E+06 - - - 1.604 - 2.469 0.549 - 391.6 1 2 0 0.0021 11 0 0 0 1.43E+09 1.32E+08 - - - 5.5403 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.17703.17703.2 0.446 12-Aug R.YLNFFTK.A sp|P12004|PCNA_HUMAN 1 931.4804 1.27 41173 17703 2 931.482187 466.7475 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3486.6 - 1.58E+06 - - - 1.9678 - 1.318 0.243 - 177.2 1 2 0 0.0018 7 0 0 0 6.34E+07 4.98E+07 - - - 1.7101 0.9964 230117_WJC_METTL3_WT_vs_EV_F05.17704.17704.2 0.192 12-Aug R.YLNFFTK[136.11].A sp|P12004|PCNA_HUMAN 1 939.4946 1.33 41174 17704 2 939.497427 470.7546 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3486.8 - 1.49E+06 - - - 3.058 - 1.32 0.251 - 174.3 1 2 0 0.0029 7 0 0 0 6.64E+07 5.01E+07 - - - 1.7737 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.17705.17705.2 0.605 14-Oct K.NVFNALIR[166.11].L "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 955.5479 1.23 41175 17705 2 955.55093 478.7812 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 9.75 3486.9 - 1.13E+06 - - - 3.2024 - 1.433 0.239 - 306.2 1 2 0 0.0031 8 0 0 0 4.94E+07 4.03E+07 - - - 1.8903 1 230117_WJC_METTL3_WT_vs_EV_F05.17706.17706.2 8.08E-07 22-Dec R.VFIGNLNTALVK[136.11].K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1295.7693 0.51 41176 17706 2 1295.771275 648.8919 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3487 - 817063 - - - 1.545 - 2.441 0.556 - 338 1 2 0 0.002 12 0 0 0 4.87E+07 9.48E+07 - - - 5.4951 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17707.17707.2 9.18E-05 16-Oct R.FLVQLDDYR.F "sp|Q9HAD4|WDR41_HUMAN,tr|D6RE66|D6RE66_HUMAN,tr|B4DK73|B4DK73_HUMAN,tr|D6RH33|D6RH33_HUMAN,tr|D6RA22|D6RA22_HUMAN,tr|B4DHS8|B4DHS8_HUMAN,tr|D6R9E7|D6R9E7_HUMAN,tr|H0YAA3|H0YAA3_HUMAN,tr|D6RBY6|D6RBY6_HUMAN,tr|H0YAI6|H0YAI6_HUMAN,tr|D6RB94|D6RB94_HUMAN" 11 1167.5924 1.81 41177 17707 2 1167.595217 584.8035 WD repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=WDR41 PE=1 SV=3 4.21 3487.1 - 741229 - - - 2.3921 - 1.958 0.365 - 452.7 1 2 0 0.0028 9 0 0 0 8.61E+06 4.74E+06 - - - 3.6799 1 230117_WJC_METTL3_WT_vs_EV_F05.17708.17708.2 3.46E-06 22-Oct R.VFIGNLNTALVK.K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1287.7551 0.52 41178 17708 2 1287.75495 644.8848 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3487.3 - 575763 - - - -0.0955 - 2.172 0.53 - 273.4 1 2 0 -0.0001 12 0 0 0 4.87E+07 9.37E+07 - - - 4.9964 1 230117_WJC_METTL3_WT_vs_EV_F05.17711.17711.2 2.40E-05 18-Nov K.IIQLLDDYPK.C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1216.6703 1.05 41181 17711 2 1216.672469 609.3424 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3487.7 - 280032 - - - 1.7499 - 2.55 0.54 - 383 1 2 0 0.0021 10 0 0 0 3.82E+08 3.65E+08 - - - 5.6417 1 230117_WJC_METTL3_WT_vs_EV_F05.17716.17716.2 0.000142 20-Dec K.LASDAGIFFTR.A "sp|Q9NR46|SHLB2_HUMAN,tr|G5E9J1|G5E9J1_HUMAN,tr|F8WFB9|F8WFB9_HUMAN,tr|B7ZC39|B7ZC39_HUMAN,tr|B7ZC38|B7ZC38_HUMAN" 5 1196.619 2.64 41185 17716 2 1196.623725 599.3168 Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2 PE=1 SV=1 5.84 3488.3 - 450413 - - - 3.9712 - 2.451 0.485 - 436.4 1 2 0 0.0048 11 0 0 0 9.67E+06 3.67E+06 - - - 5.047 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17718.17718.2 0.00885 18-Oct K.IIQLLDDYPK[136.11].C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1224.6845 1.05 41186 17718 2 1224.686624 613.3495 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3488.5 - 1.59E+06 - - - 1.7017 - 2.26 0.411 - 261.9 1 2 0 0.0021 10 0 0 0 3.82E+08 3.65E+08 - - - 4.3519 1 230117_WJC_METTL3_WT_vs_EV_F05.17720.17720.2 0.000154 15/20 K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 12.01 41188 17720 2 1204.684903 603.3481 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3488.7 - 2.82E+06 - - - 2.7642 - 2.644 0.533 - 902.3 1 2 0 0.0033 11 0 0 0 1.17E+09 9.74E+07 - - - 5.607 0.9855 230117_WJC_METTL3_WT_vs_EV_F05.17724.17724.2 0.0986 Jun-32 R.ASSGGGAGGAAGYAPVK.Y sp|P25067|CO8A2_HUMAN 1 1376.6684 2.59 41192 17724 2 1376.667335 689.3415 Collagen alpha-2(VIII) chain OS=Homo sapiens OX=9606 GN=COL8A2 PE=1 SV=2 8.63 3489.2 - 367455 - - - -0.8041 - 1.305 0.171 - 52.2 2 2 0 -0.0011 17 0 0 0 2.25E+07 8.66E+06 - - - 0.8237 0.9933 230117_WJC_METTL3_WT_vs_EV_F05.17731.17731.2 0.273 14-May R.DILIDPIR[166.11].V "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 963.5629 1.76 41196 17731 2 963.563017 482.7887 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3490 - 1.97E+06 - - - 0.1712 - 1.323 0.148 - 102.3 1 2 0 0.0002 8 0 0 0 2.62E+07 1.49E+07 - - - 0.9782 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17732.17732.2 2.75 14-Oct R.IVEVLLIK.D "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 925.6212 1.23 41197 17732 2 925.621585 463.8179 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6 3490.1 - 842451 - - - 0.4105 - 1.963 0.334 - 220.5 1 2 0 0.0004 8 0 0 0 1.91E+07 1.56E+07 - - - 3.542 0.9807 230117_WJC_METTL3_WT_vs_EV_F05.17733.17733.2 0.0268 18-Jul K.LADQIFAYYK[136.11].V "sp|Q7L576|CYFP1_HUMAN,sp|Q96F07|CYFP2_HUMAN,tr|A0A0G2JR96|A0A0G2JR96_HUMAN,tr|E7EW33|E7EW33_HUMAN,tr|H7C229|H7C229_HUMAN,tr|E7EVJ5|E7EVJ5_HUMAN,tr|A0A0G2JQT1|A0A0G2JQT1_HUMAN" 7 1238.6427 1.71 41198 17733 2 1238.638943 620.3286 Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens OX=9606 GN=CYFIP1 PE=1 SV=1 5.83 3490.2 - 318610 - - - -3.013 - 1.673 0.167 - 98.4 1 2 0 -0.0037 10 0 0 0 3.47E+06 2.03E+06 - - - 1.7097 0.9856 230117_WJC_METTL3_WT_vs_EV_F05.17734.17734.2 0.00638 20-Jun K.VLLQSALSLGR.S "sp|Q96T51|RUFY1_HUMAN,tr|H0Y9Y8|H0Y9Y8_HUMAN,tr|J3KPP6|J3KPP6_HUMAN" 3 1155.6976 1.22 41199 17734 2 1155.703943 578.8561 RUN and FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RUFY1 PE=1 SV=2 9.72 3490.4 - 317221 - - - 5.5248 - 1.5 0.254 - 66.4 1 2 0 0.0064 11 0 0 0 1.96E+06 1.61E+06 - - - 2.0119 0.9877 230117_WJC_METTL3_WT_vs_EV_F05.17738.17738.2 0.376 12-Jul R.WLITLNK.Q "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 886.5276 1.12 41201 17738 2 886.528161 444.2711 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 8.75 3490.9 - 2.27E+06 - - - 0.5888 - 1.386 0.046 - 186.5 1 2 0 0.0005 7 0 0 0 2.25E+08 2.01E+08 - - - 0.4149 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.17745.17745.3 0.0119 Sep-40 K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 16.93 41206 17745 3 1204.682091 402.5678 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3491.7 - 268107 - - - 0.43 - 1.819 0.315 - 88.5 1 2 0 0.0005 11 0 0 0 2.39E+07 1.41E+06 - - - 3.7514 1 230117_WJC_METTL3_WT_vs_EV_F05.17747.17747.2 2.47E-07 18-Nov R.EC[160.03]LNLWGYER.V sp|Q86U44|MTA70_HUMAN 1 1338.6027 29.58 41208 17747 2 1338.604487 670.3086 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3492 - 326620 - - - 1.3566 - 2.141 0.6 - 525.6 1 2 0 0.0018 10 0 0 0 9.68E+07 3.27E+06 - - - 5.597 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.17749.17749.2 0.145 12-Jul R.NIIFFGK.F sp|P36952|SPB5_HUMAN 1 837.4749 165.37 41210 17749 2 837.474057 419.7447 Serpin B5 OS=Homo sapiens OX=9606 GN=SERPINB5 PE=1 SV=2 8.75 3492.3 - 204281 - - - -0.9767 - 1.284 0.294 - 129.3 1 2 0 -0.0008 7 0 0 0 5.63E+06 3.40E+04 - - - 2.0043 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17754.17754.2 0.000449 18-Aug R.FGFGFGNGMK[136.11].Q "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 8 1068.4942 0.72 41213 17754 2 1068.494199 535.2544 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 8.75 3492.8 - 363329 - - - -0.0356 - 1.49 0.531 - 90.6 1 2 0 0 10 0 0 0 5.89E+06 8.14E+06 - - - 4.0761 1 230117_WJC_METTL3_WT_vs_EV_F05.17755.17755.2 0.00219 20-Nov F.ILFGVYGDVQR.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 1265.6768 1.27 41214 17755 2 1265.681923 633.8457 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 5.84 3492.9 - 249725 - - - 4.0303 - 2.221 0.467 - 452.2 1 1 0 0.0051 11 0 0 0 1.34E+07 1.06E+07 - - - 4.6473 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17760.17760.2 0.00177 16-Oct K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 0.87 41217 17760 2 993.58608 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 3493.6 - 1.28E+06 - - - 1.4392 - 2.241 0.31 - 437.5 1 2 0 0.0014 9 0 0 0 2.92E+07 3.36E+07 - - - 3.6647 0.9891 230117_WJC_METTL3_WT_vs_EV_F05.17770.17770.2 0.125 16-Jun K.AAIDWFDGK.E "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1021.4869 1.16 41225 17770 2 1021.49182 511.7507 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.21 3494.8 - 230138 - - - 4.8204 - 1.41 0.261 - 74.7 2 2 0 0.0049 9 0 0 0 5.59E+06 4.82E+06 - - - 1.8268 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17772.17772.2 0.000539 16-Sep K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 0.86 41227 17772 2 983.578813 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 3495 - 501514 - - - 2.4736 - 1.986 0.349 - 332.7 1 2 0 0.0024 9 0 0 0 2.91E+07 3.38E+07 - - - 3.6029 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.17774.17774.2 0.00325 16-Aug K.AENPYLFLR.G "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN" 2 1121.5869 1.34 41229 17774 2 1121.586837 561.8007 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 6.05 3495.3 - 474917 - - - -0.0963 - 1.453 0.326 - 188.2 1 2 0 -0.0001 9 0 0 0 9.45E+06 7.06E+06 - - - 2.5297 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17783.17783.2 0.000379 18-Aug K.VEDAMLMFDK.T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|A0A6Q8PHP1|A0A6Q8PHP1_HUMAN" 6 1197.541 5.54 41237 17783 2 1197.543558 599.7778 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.03 3496.3 - 592061 - - - 2.1511 - 2.021 0.457 - 205.1 1 2 0 0.0026 10 0 0 0 3.36E+07 6.07E+06 - - - 4.3795 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.17788.17788.2 1.68 14-Sep R.IVEVLLIK[136.11].D "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 933.6354 1.23 41240 17788 2 933.635135 467.825 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6 3497 - 1.12E+06 - - - -0.2892 - 1.84 0.305 - 152 1 2 0 -0.0003 8 0 0 0 1.91E+07 1.56E+07 - - - 3.1327 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17790.17790.2 0.000572 18-Aug R.FLLADNLYC[160.03]K.A sp|P61758|PFD3_HUMAN 1 1255.6271 3.88 41242 17790 2 1255.628104 628.8208 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 5.83 3497.2 - 1.05E+06 - - - 0.8036 - 1.728 0.394 - 147 1 2 0 0.001 10 0 0 0 6.06E+07 1.56E+07 - - - 3.4775 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.17794.17794.2 0.00271 18-Oct K.SFIMSSTLIR[166.11].H sp|Q9UEG4|ZN629_HUMAN 1 1163.6248 1.23 41246 17794 2 1163.62269 582.8197 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.47 3497.7 - 585586 - - - -1.8133 - 2.137 0.423 - 349.2 1 2 0 -0.0021 10 0 0 0 6.41E+06 5.22E+06 - - - 4.2843 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17795.17795.2 0.000604 18-Sep R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 29.58 41247 17795 2 1348.611237 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3497.8 - 473466 - - - 0.2195 - 1.67 0.477 - 287.6 1 2 0 0.0003 10 0 0 0 9.68E+07 3.27E+06 - - - 3.9955 0.9543 230117_WJC_METTL3_WT_vs_EV_F05.17797.17797.2 0.000281 18-Sep R.FLLADNLYC[160.03]K[136.11].A sp|P61758|PFD3_HUMAN 1 1263.6413 3.89 41249 17797 2 1263.631426 632.8279 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 5.83 3498.1 - 358639 - - - -7.81 - 1.898 0.457 - 223.7 1 2 0 -0.0099 10 0 0 0 6.06E+07 1.56E+07 - - - 4.202 0.8723 230117_WJC_METTL3_WT_vs_EV_F05.17798.17798.3 0.938 Jul-40 K.FATEAAITILR[166.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1214.6898 16.92 41250 17798 3 1214.687411 405.9039 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3498.2 - 248277 - - - -2.0022 - 1.417 0.115 - 40.6 1 2 0 -0.0024 11 0 0 0 2.32E+07 1.37E+06 - - - 0.8116 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17800.17800.2 0.00284 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 313.7 41251 17800 2 1006.57114 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3498.4 - 1.65E+06 - - - 1.2339 - 1.91 0.465 - 268 1 2 0 0.0012 9 0 0 0 7.25E+07 2.31E+05 - - - 4.3472 1 230117_WJC_METTL3_WT_vs_EV_F05.17804.17804.2 4.46E-08 18-Oct K.VDDAMLMFDK.T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1183.5253 1.35 41254 17804 2 1183.528671 592.7699 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 3.93 3498.8 - 930290 - - - 2.8212 - 2.226 0.632 - 322.8 1 2 0 0.0033 10 0 0 0 4.21E+07 3.11E+07 - - - 5.9415 0.9924 230117_WJC_METTL3_WT_vs_EV_F05.17805.17805.2 0.207 14-Aug K.LASFFLSR.V "sp|Q8IZL8|PELP1_HUMAN,tr|E7EV54|E7EV54_HUMAN,tr|C9JFV4|C9JFV4_HUMAN,tr|I3L4P1|I3L4P1_HUMAN,tr|I3L445|I3L445_HUMAN" 5 939.5178 0.72 41255 17805 2 939.522722 470.7662 "Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2" 9.75 3498.9 - 655744 - - - 5.2367 - 1.691 0.248 - 190.2 1 2 0 0.0049 8 0 0 0 7.88E+06 1.10E+07 - - - 2.4555 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17806.17806.2 0.00306 18-Dec K.VDDAMLMFDK[136.11].T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1191.5395 1.35 41256 17806 2 1191.540264 596.777 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 3.93 3499 - 535730 - - - 0.6143 - 2.74 0.316 - 628.9 1 2 0 0.0007 10 0 0 0 4.21E+07 3.11E+07 - - - 4.1883 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.17820.17820.2 0.155 14-Aug R.LDTIFFAK.Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 953.5222 2.52 41266 17820 2 953.523275 477.7684 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3500.7 - 1.51E+06 - - - 1.1075 - 1.818 0.174 - 169.1 1 2 0 0.0011 8 0 0 0 1.58E+08 6.24E+07 - - - 2.1286 0.996 230117_WJC_METTL3_WT_vs_EV_F05.17825.17825.2 0.0295 14-Jun R.NILIVLTK.L "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN,tr|H0Y815|H0Y815_HUMAN" 3 912.6008 0.89 41271 17825 2 912.601926 457.3077 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 8.75 3501 - 2.73E+06 - - - 1.2295 - 1.273 0.186 - 94.2 1 2 0 0.0011 8 0 0 0 1.13E+07 1.26E+07 - - - 1.1424 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17827.17827.2 0.165 14-Sep R.LSVLLGLK.K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 841.5637 2.39 41273 17827 2 841.564358 421.7891 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3501.2 - 1.54E+06 - - - 0.7938 - 1.774 0.328 - 199.2 1 2 0 0.0007 8 0 0 0 9.51E+06 3.99E+06 - - - 3.1923 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.17833.17833.2 0.0128 14-Aug R.LDTIFFAK[136.11].Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 961.5364 2.52 41279 17833 2 961.535743 481.7755 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3501.7 - 664990 - - - -0.703 - 2.001 0.165 - 185.1 1 2 0 -0.0007 8 0 0 0 1.58E+08 6.28E+07 - - - 2.3515 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17835.17835.2 0.00657 16-Sep R.AVALYFIDK[136.11].L "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN,tr|E5RIC7|E5RIC7_HUMAN" 4 1046.5892 1.44 41280 17835 2 1046.590685 524.3019 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 5.88 3501.9 - 2.11E+06 - - - 1.4351 - 1.848 0.372 - 292.4 1 2 0 0.0015 9 0 0 0 5.81E+07 4.02E+07 - - - 3.5648 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.17837.17837.2 0.0641 14-Aug R.ADLIAYLK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 905.5222 1.49 41282 17837 2 905.5239 453.7684 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 5.88 3502.1 - 1.50E+06 - - - 1.8564 - 1.414 0.167 - 194.9 1 2 0 0.0017 8 0 0 0 2.91E+07 1.95E+07 - - - 1.3187 1 230117_WJC_METTL3_WT_vs_EV_F05.17839.17839.2 7.89E-06 14/24 K.VLATTFDPYLGGR.N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1408.7351 10.69 41284 17839 2 1408.73791 705.3748 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3502.3 - 965526 - - - 2.0195 - 2.882 0.619 - 536 1 2 0 0.0028 13 0 0 0 5.03E+07 4.70E+06 - - - 6.3287 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.17840.17840.2 0.00022 20-Oct K.LALDMEINAYR.K sp|Q03252|LMNB2_HUMAN 1 1307.6544 0.85 41285 17840 2 1307.658052 654.8345 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.37 3502.5 - 223391 - - - 2.8142 - 2.081 0.349 - 358.9 1 2 0 0.0037 11 0 0 0 2.20E+06 2.58E+06 - - - 3.6001 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.17843.17843.2 0.224 14-Oct K.LILTPFER.N "sp|Q9H089|LSG1_HUMAN,tr|F8WFC6|F8WFC6_HUMAN" 2 987.5753 1.33 41286 17843 2 987.578884 494.7949 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 6 3502.9 - 2.22E+06 - - - 3.6119 - 1.891 0.246 - 307.9 1 2 0 0.0036 8 0 0 0 3.86E+07 2.91E+07 - - - 2.7783 0.9754 230117_WJC_METTL3_WT_vs_EV_F05.17844.17844.2 0.216 14-Aug R.GIFEPFGR.L "sp|Q14498|RBM39_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 5 921.4709 1.26 41287 17844 2 921.473978 461.7427 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 6 3502.9 - 1.34E+06 - - - 3.3924 - 1.29 0.084 - 170.9 1 2 0 0.0031 8 0 0 0 6.90E+07 5.47E+07 - - - 0.4284 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17847.17847.2 0.00393 14-Sep R.LSVLLGLK[136.11].K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 849.5779 2.4 41290 17847 2 849.579786 425.7962 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3503.3 - 365522 - - - 2.2317 - 1.761 0.39 - 201.4 1 2 0 0.0019 8 0 0 0 9.04E+06 3.77E+06 - - - 3.6276 1 230117_WJC_METTL3_WT_vs_EV_F05.17849.17849.2 8.38E-11 30-Dec K.VLAQNSGFDLQETLVK.L sp|P40227|TCPZ_HUMAN 1 1760.9309 45.81 41292 17849 2 1760.938418 881.4727 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3503.6 - 203607 - - - 4.2892 - 2.832 0.663 - 341.4 1 2 0 0.0076 16 0 0 0 3.62E+06 7.90E+04 - - - 6.4949 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.17850.17850.2 0.0158 20-Jul R.C[160.03]LAPMMSEVIR.L "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 1305.6243 1.26 41293 17850 2 1305.629706 653.8194 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 5.99 3503.7 - 181265 - - - 4.1137 - 1.643 0.328 - 150.5 1 2 0 0.0054 11 0 0 0 2.72E+06 2.16E+06 - - - 2.8051 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.17854.17854.2 0.000237 16-Aug R.FLSPEFIPR[166.11].R "sp|P49406|RM19_HUMAN,tr|A0A0A0MRF4|A0A0A0MRF4_HUMAN" 2 1114.6051 0.86 41295 17854 2 1114.60982 558.3098 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 6 3504.2 - 1.47E+06 - - - 4.2786 - 1.736 0.448 - 171.8 1 2 0 0.0048 9 0 0 0 2.85E+07 3.30E+07 - - - 3.9442 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17856.17856.2 0.0511 16-Jul R.FLSPEFIPR.R "sp|P49406|RM19_HUMAN,tr|A0A0A0MRF4|A0A0A0MRF4_HUMAN" 2 1104.5968 0.88 41297 17856 2 1104.598713 553.3057 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 6 3504.3 - 1.48E+06 - - - 1.7491 - 1.521 0.349 - 147.4 1 2 0 0.0019 9 0 0 0 2.83E+07 3.21E+07 - - - 2.8314 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17857.17857.2 9.71E-05 20-Aug K.LTPVPDSFFAK.H sp|O94906|PRP6_HUMAN 1 1220.6441 0.05 41298 17857 2 1220.647485 611.3293 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.84 3504.4 - 905118 - - - 2.7526 - 1.676 0.459 - 151.2 1 2 0 0.0034 11 0 0 0 3.32E+07 7.24E+08 - - - 3.8271 0.9872 230117_WJC_METTL3_WT_vs_EV_F05.17859.17859.2 0.00257 16-Sep K.IIGNLLYYR.Y "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1123.639 1.22 41300 17859 2 1123.647059 562.8268 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.59 3504.6 - 295006 - - - 7.19 - 1.942 0.33 - 185.6 1 2 0 0.0081 9 0 0 0 3.51E+07 2.87E+07 - - - 3.396 1 230117_WJC_METTL3_WT_vs_EV_F05.17860.17860.2 1.12E-06 13/24 K.VLATTFDPYLGGR[166.11].N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1418.7433 10.66 41301 17860 2 1418.745953 710.3789 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3504.7 - 201811 - - - 1.8453 - 2.859 0.554 - 384.7 1 2 0 0.0026 13 0 0 0 5.02E+07 4.70E+06 - - - 5.8281 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.17863.17863.2 0.00122 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 0.94 41304 17863 2 1235.765117 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3505.1 - 166689 - - - 4.0129 - 1.951 0.369 - 112.9 1 2 0 0.005 11 0 0 0 1.84E+06 1.95E+06 - - - 3.5729 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.17869.17869.2 0.79 14-Aug K.ILILQGLK.Q "sp|Q9UNX4|WDR3_HUMAN,tr|D6RCT0|D6RCT0_HUMAN" 2 896.6059 0.97 41308 17869 2 896.607179 449.3102 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 8.75 3505.8 - 312680 - - - 1.4388 - 1.56 0.158 - 173.5 1 2 0 0.0013 8 0 0 0 1.91E+07 1.97E+07 - - - 1.5487 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.17870.17870.2 0.00403 22-Aug R.IGPLSPFTNAYR[166.11].R "sp|O75486|SUPT3_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 2 1344.7066 1.65 41309 17870 2 1344.710291 673.3606 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 8.75 3505.9 - 238966 - - - 2.7776 - 1.636 0.287 - 129 1 2 0 0.0037 12 0 0 0 2.03E+07 1.23E+07 - - - 2.4548 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.17871.17871.3 0.206 Nov-36 R.FSVLLLHGIR[166.11].F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1163.7054 2.62 41310 17871 3 1163.708521 388.9091 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3506.1 - 178651 - - - 2.6527 - 2.129 0.228 - 107.6 1 2 0 0.0031 10 0 0 0 9.81E+06 3.74E+06 - - - 3.288 1 230117_WJC_METTL3_WT_vs_EV_F05.17872.17872.2 2.16E-05 28-Dec R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 5.75 41311 17872 2 1484.912848 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3506.2 - 161086 - - - 3.3423 - 2.284 0.522 - 357.2 1 2 0 0.005 15 0 0 0 1.18E+07 2.05E+06 - - - 4.9255 0.9933 230117_WJC_METTL3_WT_vs_EV_F05.17874.17874.2 0.135 28-Apr R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 7.03 41313 17874 2 1494.91752 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3506.5 - 72246.5 - - - 0.9131 - 1.206 0.259 - 34.8 25 2 0 0.0014 15 0 0 0 1.51E+07 2.14E+06 - - - 0.7896 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17877.17877.2 0.0168 14-Sep K.NILTEIYR.L sp|Q15907|RB11B_HUMAN 1 1020.5604 1.6 41315 17877 2 1020.562807 511.2875 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 6 3506.8 - 1.60E+06 - - - 2.3634 - 1.736 0.382 - 287.6 1 2 0 0.0024 8 0 0 0 5.55E+07 3.48E+07 - - - 3.5252 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17879.17879.3 0.0441 15/36 R.FSVLLLHGIR.F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1153.6972 2.15 41317 17879 3 1153.701909 385.573 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3507 - 2.19E+06 - - - 4.1129 - 2.34 0.404 - 262.3 1 2 0 0.0047 10 0 0 0 9.93E+06 4.63E+06 - - - 5.5257 0.9672 230117_WJC_METTL3_WT_vs_EV_F05.17880.17880.2 0.22 14-Aug R.ADLIAYLK[136.11].K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 913.5364 1.92 41318 17880 2 913.540523 457.7755 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 5.88 3507.1 - 1.52E+06 - - - 4.4924 - 1.479 0.071 - 185.6 1 2 0 0.0041 8 0 0 0 2.69E+07 1.41E+07 - - - 0.7445 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17881.17881.2 0.00265 18-Aug R.LITTQQWLIK.L sp|P00846|ATP6_HUMAN 1 1242.7336 1.06 41319 17881 2 1242.737759 622.3741 ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1 8.75 3507.3 - 916727 - - - 3.3394 - 2.033 0.411 - 142.2 1 2 0 0.0042 10 0 0 0 6.40E+06 6.06E+06 - - - 4.0558 1 230117_WJC_METTL3_WT_vs_EV_F05.17882.17882.2 0.000171 18-Nov R.LITTQQWLIK[136.11].L sp|P00846|ATP6_HUMAN 1 1250.7478 1.06 41320 17882 2 1250.751515 626.3812 ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1 8.75 3507.4 - 901861 - - - 2.963 - 2.19 0.457 - 337.3 1 2 0 0.0037 10 0 0 0 6.40E+06 6.06E+06 - - - 4.6033 0.9789 230117_WJC_METTL3_WT_vs_EV_F05.17885.17885.2 0.0031 24-Oct R.LPLLPPESPGPLR.Q "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN,tr|A0A669KAX5|A0A669KAX5_HUMAN" 6 1384.8078 4.23 41323 17885 2 1384.818203 693.4112 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 6 3507.8 - 215742 - - - 7.4862 - 1.838 0.312 - 281.7 1 2 0 0.0104 13 0 0 0 1.40E+06 3.32E+05 - - - 2.9044 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.17888.17888.3 4.32E-07 Dec-76 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 5.78 41326 17888 3 2187.049608 730.0199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3508.2 - 149326 - - - 5.3689 - 2.275 0.533 - 83.3 1 2 0 0.0117 20 0 0 0 7.07E+06 1.22E+06 - - - 6.4733 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.17892.17892.2 2.45E-06 13/18 R.IC[160.03]DDELILIK.N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1230.653 9.74 41329 17892 2 1230.658774 616.3338 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3508.6 - 4.83E+06 - - - 4.7113 - 2.759 0.366 - 428 1 2 0 0.0058 10 0 0 0 1.19E+09 1.22E+08 - - - 4.5753 0.9876 230117_WJC_METTL3_WT_vs_EV_F05.17893.17893.2 0.56 14-Jul K.ILILQGLK[136.11].Q "sp|Q9UNX4|WDR3_HUMAN,tr|D6RCT0|D6RCT0_HUMAN" 2 904.6201 0.97 41330 17893 2 904.623964 453.3173 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 8.75 3508.7 - 1.65E+06 - - - 4.2836 - 1.422 0.175 - 101.8 1 2 0 0.0039 8 0 0 0 1.91E+07 1.97E+07 - - - 1.3941 0.9952 230117_WJC_METTL3_WT_vs_EV_F05.17895.17895.2 0.000321 20-Oct R.LLALNSLYSPK.L sp|P78527|PRKDC_HUMAN 1 1217.702 1.25 41332 17895 2 1217.708324 609.8583 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.59 3508.9 - 882179 - - - 5.2147 - 2.142 0.255 - 267.8 1 2 0 0.0063 11 0 0 0 7.92E+07 6.35E+07 - - - 2.9831 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.17896.17896.2 0.102 18-Nov K.EVLLVALGSR.Q sp|Q10570|CPSF1_HUMAN 1 1055.6339 1.29 41333 17896 2 1055.63744 528.8242 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6.1 3509 - 721741 - - - 3.3582 - 2.362 0.294 - 431 1 2 0 0.0035 10 0 0 0 1.67E+07 1.30E+07 - - - 3.6105 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17897.17897.2 0.000123 18-Nov R.IC[160.03]DDELILIK[136.11].N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1238.6672 9.73 41334 17897 2 1238.671538 620.3409 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3509.2 - 659957 - - - 3.5215 - 2.539 0.386 - 236.9 1 2 0 0.0044 10 0 0 0 1.19E+09 1.22E+08 - - - 4.4915 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.17898.17898.2 0.464 18-Oct K.VLALLDVPDK.S sp|Q9NX62|IMPA3_HUMAN 1 1081.6383 0.95 41335 17898 2 1081.643014 541.8264 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.21 3509.3 - 414221 - - - 4.348 - 2.041 0.227 - 332.6 1 2 0 0.0047 10 0 0 0 5.11E+07 5.36E+07 - - - 2.7076 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17903.17903.2 4.38E-05 20-Aug R.AVVPSYIPLVK[136.11].K sp|P36551|HEM6_HUMAN 1 1192.7311 1.12 41338 17903 2 1192.734315 597.3728 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3510 - 1.61E+06 - - - 2.6988 - 1.78 0.431 - 213.7 1 2 0 0.0032 11 0 0 0 2.49E+08 2.22E+08 - - - 3.7832 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.17904.17904.2 1.23E-05 20-Oct R.AVVPSYIPLVK.K sp|P36551|HEM6_HUMAN 1 1184.7169 1.12 41339 17904 2 1184.720091 593.3657 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3510.1 - 1.50E+06 - - - 2.6968 - 1.715 0.473 - 370.1 1 2 0 0.0032 11 0 0 0 2.49E+08 2.22E+08 - - - 3.9928 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.17906.17906.2 0.0098 22-Nov R.IGPLSPFTNAYR.R "sp|O75486|SUPT3_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 2 1334.6983 1.65 41341 17906 2 1334.703634 668.3564 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 8.75 3510.3 - 592674 - - - 4.0069 - 2.15 0.404 - 262.9 1 2 0 0.0053 12 0 0 0 2.03E+07 1.23E+07 - - - 4.0373 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.17907.17907.2 0.000578 18-Dec K.VLALLDVPDK[136.11].S sp|Q9NX62|IMPA3_HUMAN 1 1089.6525 1.08 41342 17907 2 1089.656822 545.8335 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.21 3510.5 - 521297 - - - 3.9563 - 2.27 0.177 - 463.3 1 2 0 0.0043 10 0 0 0 5.80E+07 5.37E+07 - - - 2.6352 1 230117_WJC_METTL3_WT_vs_EV_F05.17912.17912.2 1.14E-13 17/38 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 5.87 41347 17912 2 2187.044498 1094.5262 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3511.1 - 111730 - - - 3.0324 - 3.405 0.689 - 701 1 2 0 0.0066 20 0 0 0 4.60E+06 7.85E+05 - - - 7.1402 0.9669 230117_WJC_METTL3_WT_vs_EV_F05.17917.17917.2 0.00761 18-Sep G.AGALQVVGLK[136.11].T sp|Q9P1Q0|VPS54_HUMAN 1 962.6004 2.07 41350 17917 2 962.60227 482.3075 Vacuolar protein sorting-associated protein 54 OS=Homo sapiens OX=9606 GN=VPS54 PE=1 SV=2 8.8 3511.7 - 3.28E+06 - - - 1.926 - 1.809 0.39 - 225.9 1 1 0 0.0019 10 0 0 0 2.39E+08 1.16E+08 - - - 3.5756 0.999 230117_WJC_METTL3_WT_vs_EV_F05.17918.17918.2 0.0105 14-Jul R.LFGALLER[166.11].G sp|Q9BVI4|NOC4L_HUMAN 1 927.5417 1.03 41351 17918 2 927.542998 464.7781 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3511.8 - 2.21E+06 - - - 1.3757 - 1.671 0.25 - 154.4 1 2 0 0.0013 8 0 0 0 8.98E+07 8.71E+07 - - - 2.4356 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.17919.17919.2 0.28 16-Jul R.SSIAGLLLK.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 900.5644 3.68 41352 17919 2 900.565294 451.2895 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.47 3511.8 - 590119 - - - 0.9727 - 1.588 0.208 - 111.1 1 2 0 0.0009 9 0 0 0 3.67E+07 9.98E+06 - - - 1.915 0.987 230117_WJC_METTL3_WT_vs_EV_F05.17922.17922.2 0.453 14-Aug K.NLEIELLK.L "sp|Q9NVX0|HAUS2_HUMAN,tr|H3BP24|H3BP24_HUMAN,tr|J3QT48|J3QT48_HUMAN,tr|H3BQU2|H3BQU2_HUMAN,tr|H3BP16|H3BP16_HUMAN" 5 970.5699 2.27 41355 17922 2 970.569691 486.2922 HAUS augmin-like complex subunit 2 OS=Homo sapiens OX=9606 GN=HAUS2 PE=1 SV=1 4.53 3512.1 - 118060 - - - -0.2133 - 1.388 0.083 - 158 1 2 0 -0.0002 8 0 0 0 3.61E+06 1.59E+06 - - - 0.6428 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.17927.17927.2 0.0904 14-Aug K.IDHILDAL.- "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 908.4967 - 41358 17927 2 908.498422 455.2556 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.2 3512.7 - 2.41E+06 - - - 1.8591 - 1.488 0.182 - 159.9 1 2 0 0.0017 8 0 0 0 - - - - - 1.5834 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.17929.17929.2 0.00142 20-Sep R.LLALNSLYSPK[136.11].L sp|P78527|PRKDC_HUMAN 1 1225.7162 1.25 41360 17929 2 1225.72025 613.8654 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.59 3512.8 - 4.14E+06 - - - 3.3254 - 2.064 0.398 - 217.3 1 2 0 0.0041 11 0 0 0 7.92E+07 6.35E+07 - - - 3.9397 0.9932 230117_WJC_METTL3_WT_vs_EV_F05.17932.17932.2 0.227 14-Jul R.DVDFELIK.V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 977.507 3.62 41363 17932 2 977.510168 489.7608 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3513.2 - 651214 - - - 3.2787 - 1.257 0.218 - 153.4 1 2 0 0.0032 8 0 0 0 8.96E+08 2.47E+08 - - - 1.34 1 230117_WJC_METTL3_WT_vs_EV_F05.17935.17935.2 0.000272 22-Dec K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 153.74 41366 17935 2 1474.748941 738.3781 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3513.5 - 357880 - - - 4.9731 - 2.686 0.568 - 555.4 1 2 0 0.0073 12 0 0 0 6.40E+06 4.16E+04 - - - 5.8337 1 230117_WJC_METTL3_WT_vs_EV_F05.17941.17941.2 1.41E-06 18-Sep R.VVYIFGPPVK.E sp|P49915|GUAA_HUMAN 1 1117.6536 3.19 41370 17941 2 1117.655044 559.8341 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 8.56 3514.3 - 1.06E+06 - - - 1.3206 - 2.117 0.506 - 338.1 1 2 0 0.0015 10 0 0 0 2.15E+07 6.74E+06 - - - 4.8713 0.9419 230117_WJC_METTL3_WT_vs_EV_F05.17942.17942.2 0.164 12-Sep K.LFDLLNK.K sp|Q99661|KIF2C_HUMAN 1 861.496 0.52 41371 17942 2 861.4951 431.7553 Kinesin-like protein KIF2C OS=Homo sapiens OX=9606 GN=KIF2C PE=1 SV=2 5.84 3514.4 - 281408 - - - -1.0493 - 1.327 0.002 - 217.7 1 2 0 -0.0009 7 0 0 0 4.69E+06 9.00E+06 - - - -0.0481 0.9263 230117_WJC_METTL3_WT_vs_EV_F05.17943.17943.2 0.011 16-Jul K.TVTAMDVVY.A sp|P62805|H4_HUMAN 1 997.479 - 41372 17943 2 997.480422 499.7468 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 3.8 3514.4 - 1.99E+06 - - - 1.3915 - 1.138 0.402 - 117.8 1 1 0 0.0014 9 0 0 0 - - - - - 2.3837 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.17944.17944.2 0.42 16-Aug R.VILLENLTR.F "sp|Q14999|CUL7_HUMAN,tr|A0A669KB95|A0A669KB95_HUMAN,tr|A0A669KAU7|A0A669KAU7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 4 1069.6495 1.55 41373 17944 2 1069.651373 535.832 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 5.97 3514.6 - 1.02E+06 - - - 1.709 - 1.674 0.265 - 152.1 1 2 0 0.0018 9 0 0 0 2.00E+07 1.29E+07 - - - 2.4883 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.17945.17945.2 1.13 12-Jul K.FLELLPK.D "sp|P63010|AP2B1_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 5 858.5215 1.56 41374 17945 2 858.522809 430.268 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 6 3514.7 - 465981 - - - 1.5352 - 1.309 0.225 - 142.3 1 2 0 0.0013 7 0 0 0 2.23E+07 1.43E+07 - - - 1.5556 0.999 230117_WJC_METTL3_WT_vs_EV_F05.17950.17950.2 0.496 22-Nov R.LLQTIAVLEAQR.S sp|Q8IYH5|ZZZ3_HUMAN 1 1353.798 3.49 41379 17950 2 1353.797269 677.9063 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 6 3515.4 - 194503 - - - -0.54 - 2.085 0.316 - 401.8 1 2 0 -0.0007 12 0 0 0 5.39E+06 1.54E+06 - - - 3.308 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.17952.17952.2 0.0168 14-Sep R.LFGALLER.G sp|Q9BVI4|NOC4L_HUMAN 1 917.5335 1.02 41380 17952 2 917.53603 459.774 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3515.6 - 4.34E+06 - - - 2.8097 - 1.789 0.224 - 210.1 1 2 0 0.0026 8 0 0 0 9.11E+07 8.97E+07 - - - 2.4489 0.8679 230117_WJC_METTL3_WT_vs_EV_F05.17954.17954.2 0.208 12-Aug A.IFEILEK[136.11].S "sp|P22234|PUR6_HUMAN,sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 7 898.5255 1.14 41381 17954 2 898.527096 450.27 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 4.53 3515.9 - 3.86E+06 - - - 1.754 - 1.799 0.121 - 184.8 1 1 0 0.0016 7 0 0 0 8.49E+07 7.48E+07 - - - 1.7949 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.17960.17960.2 0.118 14-Aug K.IISLDAWR.V "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 972.5393 2.01 41387 17960 2 972.538512 487.2769 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.84 3516.6 - 625034 - - - -0.7753 - 1.639 0.265 - 132.5 1 2 0 -0.0008 8 0 0 0 2.64E+07 1.31E+07 - - - 2.4882 0.985 230117_WJC_METTL3_WT_vs_EV_F05.17961.17961.2 0.608 12-Jun K.ILFFNDK[136.11].S sp|P29084|T2EB_HUMAN 1 903.4946 3.95 41388 17961 2 903.496668 452.7546 Transcription initiation factor IIE subunit beta OS=Homo sapiens OX=9606 GN=GTF2E2 PE=1 SV=1 5.84 3516.7 - 1.25E+06 - - - 2.3398 - 1.111 0.133 - 78.8 1 2 0 0.0021 7 0 0 0 2.98E+07 7.55E+06 - - - 0.3562 1 230117_WJC_METTL3_WT_vs_EV_F05.17962.17962.2 6.24E-06 20-Nov R.FPC[160.03]VVYINEVR.V sp|Q69YN4|VIR_HUMAN 1 1394.7017 2.96 41389 17962 2 1394.70322 698.3581 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 5.99 3516.9 - 246588 - - - 1.1207 - 2.102 0.528 - 567.7 1 2 0 0.0016 11 0 0 0 4.83E+06 1.63E+06 - - - 4.95 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.17964.17964.2 0.561 16-Aug K.IIGNLLYYR[166.11].Y "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1133.6472 1.22 41390 17964 2 1133.649179 567.8309 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.59 3517.1 - 90125.3 - - - 1.7016 - 1.484 0.24 - 107 1 2 0 0.0019 9 0 0 0 3.51E+07 2.87E+07 - - - 1.955 0.997 230117_WJC_METTL3_WT_vs_EV_F05.17966.17966.2 0.0905 14-Jul R.DVDFELIK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 985.5212 5.22 41391 17966 2 985.522723 493.7679 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3517.3 - 1.94E+06 - - - 1.5829 - 1.152 0.26 - 121.5 1 2 0 0.0016 8 0 0 0 7.92E+08 1.52E+08 - - - 1.3876 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.17968.17968.2 0.000125 16-Sep K.LYSLSVLYK.G "sp|O15498|YKT6_HUMAN,tr|A0A7I2V530|A0A7I2V530_HUMAN,tr|A0A7I2V3S2|A0A7I2V3S2_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 6 1084.6168 5.16 41392 17968 2 1084.620254 543.3157 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 8.5 3517.5 - 606294 - - - 3.1403 - 1.836 0.302 - 181.5 1 2 0 0.0034 9 0 0 0 2.04E+07 3.95E+06 - - - 3.0283 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17971.17971.2 0.000113 16-Oct R.LSMMLLDSR[166.11].A "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1074.5441 4.63 41395 17971 2 1074.545849 538.2793 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.84 3517.8 - 113526 - - - 1.6212 - 1.946 0.443 - 305.5 1 2 0 0.0017 9 0 0 0 6.95E+07 1.50E+07 - - - 4.2386 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.17976.17976.2 21.6 12-Sep R.LLDFLQK.R "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 875.5117 1.34 41398 17976 2 875.514072 438.7631 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.84 3518.5 - 3.15E+06 - - - 2.7618 - 1.724 0.119 - 207.2 1 2 0 0.0024 7 0 0 0 7.60E+07 5.67E+07 - - - 1.6449 0.9854 230117_WJC_METTL3_WT_vs_EV_F05.17978.17978.2 0.301 12-Aug R.LLDFLQK[136.11].R "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 883.5259 1.36 41400 17978 2 883.52746 442.7702 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.84 3518.6 - 2.78E+06 - - - 1.8177 - 1.43 0.01 - 161.1 1 2 0 0.0016 7 0 0 0 7.57E+07 5.58E+07 - - - 0.2477 0.9693 230117_WJC_METTL3_WT_vs_EV_F05.17979.17979.2 0.28 14-Jul R.LYPVLLVK.Q "sp|Q7Z7F7|RM55_HUMAN,tr|X6RIW1|X6RIW1_HUMAN" 2 943.6106 1.03 41401 17979 2 943.614017 472.8126 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 8.59 3518.7 - 661180 - - - 3.5788 - 1.085 0.145 - 130.8 1 2 0 0.0034 8 0 0 0 2.86E+07 2.78E+07 - - - 0.357 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.17986.17986.2 0.000121 16-Oct R.LSMMLLDSR.A "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1064.5358 5.06 41406 17986 2 1064.536754 533.2752 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.84 3519.6 - 2.05E+06 - - - 0.8614 - 1.717 0.457 - 328.3 1 2 0 0.0009 9 0 0 0 7.77E+07 1.53E+07 - - - 3.98 1 230117_WJC_METTL3_WT_vs_EV_F05.17996.17996.2 0.000752 18-Dec K.LYALGLVPTR[166.11].G sp|Q9NV31|IMP3_HUMAN 1 1111.6629 1.23 41414 17996 2 1111.667942 556.8387 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 8.75 3521 - 2.68E+06 - - - 4.5355 - 2.431 0.448 - 583.2 1 2 0 0.005 10 0 0 0 4.38E+07 3.55E+07 - - - 4.8279 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.17999.17999.3 2.79E-06 15/48 R.KVESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1532.845 3.55 41417 17999 3 1532.85034 511.9556 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3521.4 - 740461 - - - 3.4772 - 2.504 0.463 - 285.5 1 2 0 0.0053 13 0 0 0 4.44E+06 1.25E+06 - - - 6.1892 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.18000.18000.2 0.000107 20-Oct R.LLMLGLDNAGK.T "sp|P36404|ARL2_HUMAN,tr|V9GYD0|V9GYD0_HUMAN" 2 1143.6322 2.36 41418 18000 2 1143.637259 572.8234 ADP-ribosylation factor-like protein 2 OS=Homo sapiens OX=9606 GN=ARL2 PE=1 SV=4 5.84 3521.5 - 365870 - - - 4.4411 - 2.068 0.42 - 201.8 1 2 0 0.0051 11 0 0 0 6.10E+06 2.59E+06 - - - 4.1071 0.9938 230117_WJC_METTL3_WT_vs_EV_F05.18001.18001.2 0.0141 20-Jul K.AVFVLGDAELK.G "sp|Q93074|MED12_HUMAN,tr|Q7Z3Z5|Q7Z3Z5_HUMAN" 2 1160.6441 0.17 41419 18001 2 1160.649492 581.3293 Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens OX=9606 GN=MED12 PE=1 SV=4 4.37 3521.6 - 288061 - - - 4.6242 - 1.649 0.251 - 120.4 1 2 0 0.0054 11 0 0 0 3.18E+06 1.92E+07 - - - 2.2463 0.9926 230117_WJC_METTL3_WT_vs_EV_F05.18003.18003.2 9.81E-05 24-Oct R.KVESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1532.845 2.36 41421 18003 2 1532.855939 767.4298 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3521.9 - 171351 - - - 7.1299 - 2.033 0.486 - 245.1 1 2 0 0.0109 13 0 0 0 5.97E+05 2.53E+05 - - - 4.4481 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18008.18008.2 0.00135 14-Oct K.LDYILGLK[136.11].L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 941.5677 0.82 41424 18008 2 941.569133 471.7911 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3522.5 - 3.64E+06 - - - 1.5018 - 1.969 0.29 - 303.9 1 2 0 0.0014 8 0 0 0 3.95E+08 4.83E+08 - - - 3.2259 1 230117_WJC_METTL3_WT_vs_EV_F05.18009.18009.2 6.72E-05 14/22 K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 8.12 41425 18009 2 1332.74308 667.3774 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3522.6 - 2.49E+06 - - - 2.1977 - 2.744 0.451 - 720.5 1 2 0 0.0029 12 0 0 0 5.01E+09 6.17E+08 - - - 5.0271 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.18010.18010.2 0.00612 14-Sep K.LDYILGLK.L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 933.5535 0.82 41426 18010 2 933.556262 467.784 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3522.7 - 1.91E+06 - - - 2.9382 - 1.779 0.322 - 256.6 1 2 0 0.0027 8 0 0 0 3.94E+08 4.81E+08 - - - 3.1558 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18012.18012.2 2.13E-06 22-Oct K.LFVTNDAATILR[166.11].E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1342.7484 8.12 41428 18012 2 1342.751277 672.3815 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3522.9 - 428305 - - - 2.127 - 2.112 0.475 - 310 1 2 0 0.0029 12 0 0 0 5.01E+09 6.17E+08 - - - 4.5156 0.958 230117_WJC_METTL3_WT_vs_EV_F05.18014.18014.2 0.355 20-Jul K.AVFVLGDAELK[136.11].G "sp|Q93074|MED12_HUMAN,tr|Q7Z3Z5|Q7Z3Z5_HUMAN" 2 1168.6583 0.14 41430 18014 2 1168.664741 585.3364 Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens OX=9606 GN=MED12 PE=1 SV=4 4.37 3523.1 - 256048 - - - 5.4901 - 1.421 0.145 - 79.2 1 2 0 0.0064 11 0 0 0 3.18E+06 2.35E+07 - - - 1.0605 0.997 230117_WJC_METTL3_WT_vs_EV_F05.18020.18020.2 0.00161 16-Oct R.VVLPYLVPK.L sp|Q92616|GCN1_HUMAN 1 1026.6478 1.2 41434 18020 2 1026.652437 514.3312 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.56 3523.9 - 424687 - - - 4.5614 - 1.677 0.336 - 297.5 1 2 0 0.0047 9 0 0 0 4.44E+07 3.69E+07 - - - 3.017 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.18023.18023.2 2.28 14-Aug R.LLILMEAR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 967.5764 1.63 41437 18023 2 967.578072 484.7955 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6 3524.3 - 178516 - - - 1.7353 - 1.537 0.259 - 192.9 1 2 0 0.0017 8 0 0 0 3.59E+07 2.21E+07 - - - 2.2498 0.9787 230117_WJC_METTL3_WT_vs_EV_F05.18024.18024.2 0.00909 20-Nov R.SALLVQLATAR.P "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1141.6819 2.4 41438 18024 2 1141.682947 571.8482 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 9.47 3524.5 - 153848 - - - 0.9101 - 2.519 0.394 - 350.5 1 1 0 0.001 11 0 0 0 3.65E+07 1.52E+07 - - - 4.45 0.9768 230117_WJC_METTL3_WT_vs_EV_F05.18028.18028.2 0.242 14-Jul R.LYPVLLVK[136.11].Q "sp|Q7Z7F7|RM55_HUMAN,tr|X6RIW1|X6RIW1_HUMAN" 2 951.6248 1.03 41440 18028 2 951.628732 476.8197 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 8.59 3524.9 - 1.38E+06 - - - 4.0898 - 1.021 0.23 - 119.5 1 2 0 0.0039 8 0 0 0 2.86E+07 2.78E+07 - - - 0.8012 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.18031.18031.2 0.155 16-Jul K.LFLVQLQEK[136.11].A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1124.6685 1.17 41443 18031 2 1124.672353 563.3415 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3525.3 - 725526 - - - 3.4295 - 1.523 0.321 - 96 1 2 0 0.0039 9 0 0 0 3.44E+07 2.94E+07 - - - 2.6278 0.9288 230117_WJC_METTL3_WT_vs_EV_F05.18035.18035.2 2.03 20-May R.QLIPGDEFALR.E "sp|P61371|ISL1_HUMAN,tr|D6RBJ1|D6RBJ1_HUMAN" 2 1257.6717 2.3 41447 18035 2 1257.674217 629.8431 Insulin gene enhancer protein ISL-1 OS=Homo sapiens OX=9606 GN=ISL1 PE=1 SV=1 4.37 3525.8 - 221821 - - - 1.9719 - 1.047 0.038 - 94.4 3 2 0 0.0025 11 0 0 0 2.35E+06 1.03E+06 - - - -0.768 0.9963 230117_WJC_METTL3_WT_vs_EV_F05.18040.18040.2 0.528 12-May R.GWLNIVR.H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 856.4919 1.6 41450 18040 2 856.492695 429.2532 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 9.75 3526.5 - 821040 - - - 0.9025 - 1.152 0.238 - 108 1 2 0 0.0008 7 0 0 0 2.19E+07 1.37E+07 - - - 1.247 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.18041.18041.2 2.95 14-Jul R.LLILMEAR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 957.5681 1.63 41451 18041 2 957.570591 479.7913 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6 3526.6 - 1.01E+06 - - - 2.5774 - 1.639 0.179 - 139.7 1 2 0 0.0025 8 0 0 0 3.59E+07 2.20E+07 - - - 1.8525 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18042.18042.2 0.000505 18-Aug K.IVLLMAYSGK.G "sp|Q9Y606|TRUA_HUMAN,tr|G8JLB3|G8JLB3_HUMAN,tr|F8W9U5|F8W9U5_HUMAN,tr|F5H168|F5H168_HUMAN,tr|F5H1B2|F5H1B2_HUMAN,tr|F5GY32|F5GY32_HUMAN,tr|F5GXL3|F5GXL3_HUMAN" 7 1093.6206 5.15 41452 18042 2 1093.621199 547.8176 tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3 8.59 3526.8 - 585687 - - - 0.5907 - 1.62 0.373 - 87.7 1 2 0 0.0006 10 0 0 0 1.61E+07 3.12E+06 - - - 3.1424 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18049.18049.2 9.37E-05 16-Sep K.LLQDFFNGK.E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1080.5604 8.64 41456 18049 2 1080.562357 541.2875 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3527.6 - 889037 - - - 1.8157 - 1.738 0.469 - 190.8 1 2 0 0.002 9 0 0 0 1.17E+08 1.35E+07 - - - 4.1035 0.8918 230117_WJC_METTL3_WT_vs_EV_F05.18051.18051.2 6.08 12-May R.SLSDLFR[166.11].R "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 846.4475 1.13 41458 18051 2 846.450108 424.231 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 5.55 3527.8 - 934654 - - - 3.0953 - 1.218 0.011 - 59.7 10 2 0 0.0026 7 0 0 0 2.93E+07 2.59E+07 - - - -0.7004 0.996 230117_WJC_METTL3_WT_vs_EV_F05.18052.18052.2 0.105 16-Jul K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 9.34 41459 18052 2 1014.538119 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3528 - 575926 - - - 3.4932 - 1.654 0.194 - 92.1 1 2 0 0.0035 9 0 0 0 2.47E+07 2.64E+06 - - - 1.9285 1 230117_WJC_METTL3_WT_vs_EV_F05.18053.18053.2 0.000202 20-Dec K.LIVAYVDDLDR.R "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1290.682 1.25 41460 18053 2 1290.683184 646.3483 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 3.93 3528.1 - 465122 - - - 0.9429 - 2.324 0.502 - 573 1 2 0 0.0012 11 0 0 0 9.38E+06 7.51E+06 - - - 5.0297 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18054.18054.2 0.000594 16-Sep K.WEGNYLFPR[166.11].E "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 1190.5748 1.18 41461 18054 2 1190.576635 596.2947 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3528.2 - 559839 - - - 1.5304 - 1.594 0.343 - 222.4 1 2 0 0.0018 9 0 0 0 5.12E+06 4.33E+06 - - - 2.9227 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18059.18059.2 0.00652 16-Aug R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 340.45 41465 18059 2 1006.570233 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3528.8 - 688203 - - - 0.3328 - 1.525 0.415 - 147.9 1 2 0 0.0003 9 0 0 0 9.84E+07 2.89E+05 - - - 3.3269 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.18061.18061.2 0.0476 12-Jun R.AVFWDIK.N sp|Q6P2Q9|PRP8_HUMAN 1 877.4698 1.18 41467 18061 2 877.470616 439.7422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3529 - 1.44E+06 - - - 0.9413 - 1.253 0.339 - 127.1 1 2 0 0.0008 7 0 0 0 8.45E+07 7.18E+07 - - - 2.2592 0.9957 230117_WJC_METTL3_WT_vs_EV_F05.18062.18062.2 0.561 16-Jun R.VVLPYLVPK[136.11].L sp|Q92616|GCN1_HUMAN 1 1034.662 1.2 41468 18062 2 1034.662738 518.3383 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.56 3529.1 - 1.33E+06 - - - 0.7577 - 1.15 0.248 - 114.5 2 2 0 0.0008 9 0 0 0 4.44E+07 3.69E+07 - - - 1.1424 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18064.18064.2 0.00838 16-Sep K.VLEALQVLR.C "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1039.639 1.43 41470 18064 2 1039.640261 520.8268 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.97 3529.1 - 900324 - - - 1.2322 - 1.946 0.398 - 266.5 1 2 0 0.0013 9 0 0 0 4.99E+07 3.48E+07 - - - 3.9064 0.9878 230117_WJC_METTL3_WT_vs_EV_F05.18067.18067.2 1.98 20-Jul R.TINMQQSQVEK.Y "sp|Q8N6V9|TEX9_HUMAN,tr|H3BS88|H3BS88_HUMAN,tr|H0YLZ3|H0YLZ3_HUMAN" 3 1304.6395 6.4 41473 18067 2 1304.641065 653.327 Testis-expressed protein 9 OS=Homo sapiens OX=9606 GN=TEX9 PE=1 SV=1 5.66 3529.4 - 351377 - - - 1.2371 - 1.356 0.064 - 155.6 1 2 0 0.0016 11 0 0 0 8.26E+06 1.29E+06 - - - 0.337 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18070.18070.2 0.00276 14-Sep R.YQDILVFR.S "sp|P19623|SPEE_HUMAN,tr|K7EKM4|K7EKM4_HUMAN" 2 1052.5655 6.62 41474 18070 2 1052.566103 527.29 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.84 3529.8 - 2.94E+06 - - - 0.5909 - 1.944 0.456 - 251.6 1 2 0 0.0006 8 0 0 0 1.14E+08 1.73E+07 - - - 4.4137 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18072.18072.2 0.000747 14-Oct R.VVDLLVIK.G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 897.5899 2.11 41476 18072 2 897.590296 449.8022 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3530 - 2.15E+06 - - - 0.4356 - 1.777 0.475 - 271.8 1 2 0 0.0004 8 0 0 0 1.51E+08 7.16E+07 - - - 4.2832 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18074.18074.2 2.17E-05 16-Oct R.LIDFLEC[160.03]GK.T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1093.5478 1.05 41478 18074 2 1093.548269 547.7812 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3530.3 - 745032 - - - 0.4453 - 1.758 0.471 - 215.2 1 2 0 0.0005 9 0 0 0 1.77E+08 1.69E+08 - - - 4.1518 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18080.18080.2 0.000756 14-Sep R.VVDLLVIK[136.11].G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 905.6041 2.11 41482 18080 2 905.603804 453.8093 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3531.1 - 861038 - - - -0.3324 - 1.711 0.418 - 194.5 1 2 0 -0.0003 8 0 0 0 1.51E+08 7.16E+07 - - - 3.7481 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18081.18081.2 0.0262 16-Sep K.LFLVQLQEK.A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1116.6543 1.11 41483 18081 2 1116.655181 559.3344 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3531.1 - 496841 - - - 0.7925 - 1.912 0.381 - 257.5 1 2 0 0.0009 9 0 0 0 3.16E+07 2.84E+07 - - - 3.7299 1 230117_WJC_METTL3_WT_vs_EV_F05.18088.18088.2 2.86E-07 15/30 R.IINEPTAAAIAYGLDK.R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1658.8879 33.62 41488 18088 2 1658.888579 830.4512 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3531.9 - 1.84E+06 - - - 0.387 - 2.653 0.533 - 423.1 1 2 0 0.0006 16 0 0 0 3.68E+07 1.10E+06 - - - 5.3763 0.9725 230117_WJC_METTL3_WT_vs_EV_F05.18091.18091.2 2.87 12-Jul R.ALLFIPR.R "sp|P08238|HS90B_HUMAN,sp|O00585|CCL21_HUMAN,tr|Q5VZ73|Q5VZ73_HUMAN" 3 828.5222 2.06 41489 18091 2 828.521556 415.2684 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 9.79 3532.3 - 1.61E+06 - - - -0.7278 - 1.436 0.038 - 187.2 2 2 0 -0.0006 7 0 0 0 5.02E+08 2.43E+08 - - - 0.3336 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18093.18093.2 0.0118 18-Dec K.LAVNMVPFPR[166.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1152.6353 3.12 41491 18093 2 1152.636259 577.3249 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3532.4 - 7.22E+06 - - - 0.8277 - 1.943 0.285 - 654.3 1 2 0 0.001 10 0 0 0 8.46E+08 2.72E+08 - - - 2.9998 1 230117_WJC_METTL3_WT_vs_EV_F05.18095.18095.2 2.87E-05 18-Oct K.FYALDPSFPR.M sp|Q08J23|NSUN2_HUMAN 1 1211.5975 1.74 41493 18095 2 1211.598383 606.806 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3532.7 - 655804 - - - 0.7214 - 1.807 0.53 - 341 1 2 0 0.0009 10 0 0 0 2.62E+07 1.51E+07 - - - 4.6068 0.9785 230117_WJC_METTL3_WT_vs_EV_F05.18105.18105.2 0.0119 16-Jun R.LIDFLEC[160.03]GK[136.11].T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1101.562 1.1 41501 18105 2 1101.556903 551.7883 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3534 - 8.51E+06 - - - -4.6107 - 1.265 0.388 - 72 1 2 0 -0.0051 9 0 0 0 1.71E+08 1.56E+08 - - - 2.5852 0.9572 230117_WJC_METTL3_WT_vs_EV_F05.18106.18106.2 14.6 12-Jul R.ALLFIPR[166.11].R "sp|P08238|HS90B_HUMAN,sp|O00585|CCL21_HUMAN,tr|Q5VZ73|Q5VZ73_HUMAN" 3 838.5304 2.06 41502 18106 2 838.530923 420.2725 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 9.79 3534 - 2.72E+06 - - - 0.5891 - 1.206 0.022 - 249 3 2 0 0.0005 7 0 0 0 5.02E+08 2.43E+08 - - - -0.4163 0.9058 230117_WJC_METTL3_WT_vs_EV_F05.18107.18107.2 0.00334 16-Oct R.PLVETIFER[166.11].G "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 1112.6105 0.94 41503 18107 2 1112.615377 557.3125 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.53 3534.1 - 2.72E+06 - - - 4.3564 - 2.113 0.405 - 417.8 1 1 0 0.0048 9 0 0 0 6.71E+07 7.11E+07 - - - 4.1951 0.9806 230117_WJC_METTL3_WT_vs_EV_F05.18109.18109.2 0.665 12-Jun R.LVVLPFR[166.11].R sp|Q10570|CPSF1_HUMAN 1 852.5461 2.09 41505 18109 2 852.546226 427.2803 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 9.75 3534.4 - 633999 - - - 0.1724 - 1.216 0.076 - 113.7 1 2 0 0.0001 7 0 0 0 3.23E+07 1.54E+07 - - - 0.222 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18112.18112.2 0.00779 18-Aug K.YLAIAPPIIK[136.11].Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1105.6991 1.91 41506 18112 2 1105.70048 553.8568 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3534.8 - 1.13E+06 - - - 1.277 - 1.656 0.376 - 150.5 1 2 0 0.0014 10 0 0 0 1.78E+08 9.29E+07 - - - 3.2256 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.18118.18118.3 0.00377 Sep-36 K.LAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1142.627 4.27 41512 18118 3 1142.627076 381.883 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3535.4 - 217473 - - - 0.0359 - 1.68 0.312 - 141.5 1 2 0 0 10 0 0 0 6.97E+06 1.63E+06 - - - 3.5336 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18122.18122.2 0.000652 18-Sep K.FYALDPSFPR[166.11].M sp|Q08J23|NSUN2_HUMAN 1 1221.6058 1.74 41514 18122 2 1221.606807 611.8102 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3535.9 - 483665 - - - 0.8415 - 1.586 0.372 - 262.9 1 2 0 0.001 10 0 0 0 2.76E+07 1.59E+07 - - - 3.0757 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18123.18123.3 0.004 Nov-44 K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 8.97 41515 18123 3 1332.743564 445.254 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3536 - 6.82E+06 - - - 2.5609 - 2.046 0.329 - 131 1 2 0 0.0034 12 0 0 0 9.46E+07 1.06E+07 - - - 4.1914 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18124.18124.2 0.000266 18-Sep R.VLITTDLLAR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 1123.684 1.51 41516 18124 2 1123.687487 562.8493 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3536.1 - 3.29E+06 - - - 3.0765 - 1.992 0.404 - 176.5 1 2 0 0.0035 10 0 0 0 2.77E+08 1.84E+08 - - - 3.9475 0.9657 230117_WJC_METTL3_WT_vs_EV_F05.18128.18128.2 8.44 12-May K.IVIPILK.Y "sp|Q8NCM8|DYHC2_HUMAN,sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|A0A3B3ISP9|A0A3B3ISP9_HUMAN,tr|F6XAQ5|F6XAQ5_HUMAN" 6 794.563 1.36 41520 18128 2 794.563782 398.2888 Cytoplasmic dynein 2 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC2H1 PE=1 SV=4 8.75 3536.6 - 390144 - - - 1.032 - 1.138 0.065 - 53.2 4 2 0 0.0008 7 0 0 0 7.57E+06 5.57E+06 - - - -0.3385 0.9297 230117_WJC_METTL3_WT_vs_EV_F05.18135.18135.2 0.00851 12-Aug H.ILLWDTR.N "sp|Q9BTV6|DPH7_HUMAN,sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 3 915.5178 0.45 41525 18135 2 915.517798 458.7662 Diphthine methyltransferase OS=Homo sapiens OX=9606 GN=DPH7 PE=1 SV=2 5.84 3537.4 - 8.64E+06 - - - -0.0044 - 1.729 0.286 - 260.6 1 1 0 0 7 0 0 0 5.78E+08 1.28E+09 - - - 2.8883 0.9607 230117_WJC_METTL3_WT_vs_EV_F05.18137.18137.2 0.000578 18-Oct N.MVVDAVLAIK.Y "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1057.6206 22.53 41527 18137 2 1057.621108 529.8176 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.59 3537.5 - 1.91E+06 - - - 0.5248 - 1.759 0.377 - 241 1 1 0 0.0006 10 0 0 0 1.88E+07 8.34E+05 - - - 3.4017 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.18139.18139.2 0.0166 18-Sep K.MLLAISELNK.N sp|Q9H694|BICC1_HUMAN 1 1130.6369 2.14 41529 18139 2 1130.6401 566.3257 Protein bicaudal C homolog 1 OS=Homo sapiens OX=9606 GN=BICC1 PE=1 SV=2 5.75 3537.7 - 994514 - - - 2.8028 - 1.407 0.331 - 205.4 1 2 0 0.0032 10 0 0 0 6.11E+06 2.85E+06 - - - 2.4379 0.8964 230117_WJC_METTL3_WT_vs_EV_F05.18142.18142.2 5.74 14-May K.RASIQYSK[136.11].D "sp|Q10588|BST1_HUMAN,tr|H0Y8G4|H0Y8G4_HUMAN,tr|A6NC48|A6NC48_HUMAN,tr|H0Y984|H0Y984_HUMAN" 4 959.528 - 41532 18142 2 959.528909 480.7713 ADP-ribosyl cyclase\cyclic ADP-ribose hydrolase 2 OS=Homo sapiens OX=9606 GN=BST1 PE=1 SV=2 9.99 3538.1 - 667189 - - - 0.9682 - 1.068 0.042 - 44.9 23 2 0 0.0009 8 0 0 0 - - - - - -1.059 1 230117_WJC_METTL3_WT_vs_EV_F05.18143.18143.2 8.65E-06 26-Dec K.IIVPNSTAGLIIGK.G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VW64|F8VW64_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|M0R1A0|M0R1A0_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|G8JLA5|G8JLA5_HUMAN" 8 1394.8497 2.27 41533 18143 2 1394.853493 698.4321 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.75 3538.3 - 659588 - - - 2.7186 - 1.941 0.543 - 292.4 1 2 0 0.0038 14 0 0 0 3.11E+06 1.37E+06 - - - 4.7147 1 230117_WJC_METTL3_WT_vs_EV_F05.18148.18148.2 3.39E-05 22-Dec R.FLAVGLVDNTVR[166.11].L sp|Q15393|SF3B3_HUMAN 1 1312.7379 1.13 41536 18148 2 1312.740925 657.3762 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3538.9 - 464368 - - - 2.3379 - 2.12 0.498 - 487.7 1 2 0 0.0031 12 0 0 0 1.49E+08 1.31E+08 - - - 4.6954 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18149.18149.2 0.000403 22-Sep R.FLAVGLVDNTVR.L sp|Q15393|SF3B3_HUMAN 1 1302.7296 1.13 41537 18149 2 1302.732519 652.3721 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3539 - 488753 - - - 2.2514 - 2.042 0.406 - 260.2 1 2 0 0.0029 12 0 0 0 1.49E+08 1.31E+08 - - - 3.9173 0.999 230117_WJC_METTL3_WT_vs_EV_F05.18154.18154.2 0.0456 14-Aug R.IGVMSLIR[166.11].K "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 897.5345 1.43 41540 18154 2 897.536877 449.7745 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 3539.7 - 2.54E+06 - - - 2.6161 - 1.534 0.331 - 186.7 1 2 0 0.0023 8 0 0 0 4.41E+07 3.07E+07 - - - 2.7755 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18156.18156.2 0.00613 18-Sep K.YLAIAPPIIK.Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1097.6849 1.91 41542 18156 2 1097.68596 549.8497 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3539.8 - 1.22E+07 - - - 0.9948 - 1.582 0.379 - 283.2 1 2 0 0.0011 10 0 0 0 1.78E+08 9.29E+07 - - - 3.1203 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18157.18157.2 0.000124 20-Nov K.LDPGLIMEQVK.V sp|Q9Y5L4|TIM13_HUMAN 1 1241.669 2.14 41543 18157 2 1241.67255 621.8418 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3539.9 - 662870 - - - 2.8913 - 2.031 0.409 - 466.3 1 2 0 0.0036 11 0 0 0 1.76E+07 8.23E+06 - - - 3.9775 0.9658 230117_WJC_METTL3_WT_vs_EV_F05.18158.18158.2 3.68E-05 22-Nov R.APVVAIAVLDGR.G "sp|Q15334|L2GL1_HUMAN,tr|A0A087WW77|A0A087WW77_HUMAN" 2 1179.6976 1.73 41544 18158 2 1179.689195 590.8561 Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens OX=9606 GN=LLGL1 PE=1 SV=3 5.88 3540 - 634943 - - - -7.0891 - 2.587 0.349 - 385.5 1 2 0 -0.0084 12 0 0 0 7.69E+06 4.46E+06 - - - 4.117 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.18166.18166.2 0.0337 18-Nov R.ILELDQELIK.A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1212.6966 1.29 41550 18166 2 1212.697354 607.3556 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3541 - 2.46E+06 - - - 0.6589 - 1.836 0.251 - 331.3 1 2 0 0.0008 10 0 0 0 4.36E+07 3.37E+07 - - - 2.5906 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18167.18167.2 0.00304 14-Jul R.IGVMSLIR.K "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 887.5263 1.43 41551 18167 2 887.526697 444.7704 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 3541 - 5.31E+06 - - - 0.4935 - 1.699 0.356 - 121.2 1 2 0 0.0004 8 0 0 0 4.39E+07 3.06E+07 - - - 3.2689 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.18168.18168.2 0.0812 18-Nov R.ILELDQELIK[136.11].A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1220.7108 1.29 41552 18168 2 1220.711006 611.3627 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3541.1 - 2.08E+06 - - - 0.2056 - 2.166 0.242 - 324.4 1 2 0 0.0003 10 0 0 0 4.32E+07 3.34E+07 - - - 2.9857 0.998 230117_WJC_METTL3_WT_vs_EV_F05.18169.18169.2 0.0845 16-Sep K.TLGILGLGR[166.11].L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 908.5683 2 41553 18169 2 908.568974 455.2914 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3541.2 - 1.69E+06 - - - 0.7726 - 1.551 0.198 - 277.6 1 2 0 0.0007 9 0 0 0 3.21E+08 1.61E+08 - - - 1.773 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18170.18170.2 0.00169 20-Oct R.LGIPDAVSYIK.K sp|O94874|UFL1_HUMAN 1 1174.6598 1.04 41554 18170 2 1174.659917 588.3372 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.83 3541.3 - 1.19E+06 - - - 0.1209 - 2.121 0.387 - 177.6 1 2 0 0.0001 11 0 0 0 2.49E+07 2.39E+07 - - - 3.9334 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18172.18172.2 0.128 20-Nov K.LALDMEISAYR.K "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN" 2 1280.6435 1.58 41556 18172 2 1280.645066 641.329 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.37 3541.5 - 928920 - - - 1.2439 - 2.297 0.359 - 573.1 1 2 0 0.0016 11 0 0 0 7.61E+06 4.82E+06 - - - 3.9418 1 230117_WJC_METTL3_WT_vs_EV_F05.18173.18173.2 9.02E-05 26-Dec K.VLIPSYAAGSIIGK.G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|F8W659|F8W659_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|F8VYI3|F8VYI3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|I3L2B5|I3L2B5_HUMAN" 8 1387.8075 3.68 41557 18173 2 1387.808793 694.911 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.56 3541.6 - 753501 - - - 0.9302 - 2.096 0.545 - 270.3 1 2 0 0.0013 14 0 0 0 9.38E+06 2.55E+06 - - - 4.923 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18174.18174.2 0.000332 20-Nov K.LDPGLIMEQVK[136.11].V sp|Q9Y5L4|TIM13_HUMAN 1 1249.6832 2.14 41558 18174 2 1249.686387 625.8489 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3541.8 - 669892 - - - 2.5823 - 1.949 0.387 - 495.3 1 2 0 0.0032 11 0 0 0 1.76E+07 8.23E+06 - - - 3.7036 0.997 230117_WJC_METTL3_WT_vs_EV_F05.18177.18177.2 0.00313 20-Sep K.NLIDAGVDALR[166.11].V "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1165.6331 0.91 41561 18177 2 1165.631483 583.8238 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.21 3542.1 - 517685 - - - -1.3503 - 1.824 0.251 - 176.1 1 2 0 -0.0016 11 0 0 0 4.23E+06 4.66E+06 - - - 2.5203 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18184.18184.2 0.00862 16-Jul R.YYIDADLLR.E sp|Q7Z3B4|NUP54_HUMAN 1 1140.5815 2.91 41566 18184 2 1140.584555 571.298 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.21 3542.9 - 5.32E+06 - - - 2.6565 - 1.446 0.452 - 123.4 1 2 0 0.003 9 0 0 0 6.75E+07 2.32E+07 - - - 3.4455 0.9869 230117_WJC_METTL3_WT_vs_EV_F05.18185.18185.2 2.53 16-Sep K.TLGILGLGR.L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 898.56 1.99 41567 18185 2 898.56318 450.2873 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3543 - 5.64E+06 - - - 3.5368 - 1.63 0.068 - 249.3 1 2 0 0.0032 9 0 0 0 3.24E+08 1.63E+08 - - - 0.9557 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.18187.18187.2 0.0142 16-Jul R.YYIDADLLR[166.11].E sp|Q7Z3B4|NUP54_HUMAN 1 1150.5898 2.91 41569 18187 2 1150.591519 576.3022 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.21 3543.1 - 2.27E+06 - - - 1.4984 - 1.367 0.321 - 134.9 1 2 0 0.0017 9 0 0 0 6.75E+07 2.32E+07 - - - 2.3158 1 230117_WJC_METTL3_WT_vs_EV_F05.18188.18188.2 0.000138 20-Nov R.VVGVLLGSWQK.K "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 1184.6917 1.52 41570 18188 2 1184.694858 593.3531 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 8.72 3543.1 - 2.24E+06 - - - 2.6285 - 2.109 0.545 - 414.2 1 2 0 0.0031 11 0 0 0 2.47E+07 1.62E+07 - - - 5.0841 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.18189.18189.2 0.109 20-Sep R.VVGVLLGSWQK[136.11].K "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 1192.7059 1.53 41571 18189 2 1192.706663 597.3602 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 8.72 3543.2 - 1.65E+06 - - - 0.6028 - 1.929 0.263 - 250.5 1 2 0 0.0007 11 0 0 0 2.48E+07 1.62E+07 - - - 2.7606 1 230117_WJC_METTL3_WT_vs_EV_F05.18191.18191.2 0.0057 22-Nov K.IPGIIIAASAVR.A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1179.7339 2.46 41573 18191 2 1179.743158 590.8742 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3543.3 - 933310 - - - 7.8111 - 2.338 0.469 - 421.8 1 2 0 0.0092 12 0 0 0 4.83E+07 1.96E+07 - - - 4.7368 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18196.18196.2 3.26E-06 24-Nov -.MLSEVLLVSAPGK[136.11].V "sp|Q03426|KIME_HUMAN,tr|F5GXC0|F5GXC0_HUMAN,tr|F5H163|F5H163_HUMAN,tr|F5H092|F5H092_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|F5H368|F5H368_HUMAN,tr|A0A1W2PS16|A0A1W2PS16_HUMAN" 7 1350.7672 5.73 41578 18196 2 1350.767568 676.3909 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 5.75 3544 - 208254 - - - 0.2547 - 2.055 0.481 - 343.3 1 2 0 0.0003 13 0 0 0 1.30E+07 2.26E+06 - - - 4.4422 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.18198.18198.2 0.5 14-Jul R.SSLLLGFR.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 891.5178 0.88 41579 18198 2 891.518166 446.7662 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 9.47 3544.2 - 4.71E+06 - - - 0.4083 - 1.67 0.263 - 194.9 1 2 0 0.0004 8 0 0 0 4.48E+07 5.08E+07 - - - 2.5301 0.9679 230117_WJC_METTL3_WT_vs_EV_F05.18199.18199.2 1.97 14-Apr R.DVDFELIK.V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 977.507 3.38 41580 18199 2 977.508019 489.7608 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3544.3 - 611136 - - - 1.0803 - 1.033 0.156 - 36.5 21 2 0 0.0011 8 0 0 0 8.98E+08 2.66E+08 - - - -0.2998 0.9963 230117_WJC_METTL3_WT_vs_EV_F05.18204.18204.3 0.589 Oct-44 R.FLAVGLVDNTVR[166.11].L sp|Q15393|SF3B3_HUMAN 1 1312.7379 2.44 41585 18204 3 1312.738889 438.5866 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3544.7 - 1.06E+06 - - - 0.7869 - 1.681 0.199 - 65.3 1 2 0 0.001 12 0 0 0 9.26E+06 3.79E+06 - - - 2.198 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.18205.18205.3 0.000223 Nov-44 R.FLAVGLVDNTVR.L sp|Q15393|SF3B3_HUMAN 1 1302.7296 1.5 41586 18205 3 1302.73127 435.2505 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3544.9 - 940907 - - - 1.2927 - 2.067 0.361 - 111.9 1 2 0 0.0017 12 0 0 0 4.93E+06 3.28E+06 - - - 4.577 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18208.18208.2 7.61E-05 28-Sep R.LGALQGDPEALTLYR.E sp|Q9P253|VPS18_HUMAN 1 1615.857 13.62 41589 18208 2 1615.85985 808.9358 Vacuolar protein sorting-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=VPS18 PE=1 SV=2 4.37 3545.3 - 654131 - - - 1.7811 - 1.997 0.467 - 190.3 1 2 0 0.0029 15 0 0 0 2.98E+06 2.19E+05 - - - 4.1898 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.18215.18215.2 3.84 12-Jun K.MIADFLR.E "sp|Q96R72|OR4K3_HUMAN,sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 4 864.4528 3.85 41594 18215 2 864.453115 433.2337 Olfactory receptor 4K3 OS=Homo sapiens OX=9606 GN=OR4K3 PE=3 SV=3 5.59 3546.2 - 1.68E+06 - - - 0.4118 - 1.392 0.178 - 181.7 1 2 0 0.0004 7 0 0 0 4.73E+07 1.23E+07 - - - 1.4036 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.18216.18216.2 0.755 12-Jul K.ILVDLLK.L "sp|Q6P582|MZT2A_HUMAN,sp|Q6NZ67|MZT2B_HUMAN,tr|H7C202|H7C202_HUMAN,tr|B8ZZ87|B8ZZ87_HUMAN,tr|A0A494C0V9|A0A494C0V9_HUMAN,tr|H7BZ50|H7BZ50_HUMAN,tr|H7C173|H7C173_HUMAN" 7 812.5371 2.46 41595 18216 2 812.537447 407.2758 Mitotic-spindle organizing protein 2A OS=Homo sapiens OX=9606 GN=MZT2A PE=1 SV=2 5.84 3546.3 - 927473 - - - 0.3766 - 1.763 0.229 - 123.7 1 2 0 0.0003 7 0 0 0 1.58E+07 6.40E+06 - - - 2.5289 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18218.18218.2 0.000542 22-Oct K.LIVDPALDPALR.R "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN,tr|C9J2Z9|C9J2Z9_HUMAN" 3 1291.75 2.48 41597 18218 2 1291.75294 646.8823 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.21 3546.5 - 979446 - - - 2.286 - 1.822 0.432 - 257.9 1 2 0 0.003 12 0 0 0 1.97E+07 7.95E+06 - - - 3.8094 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18231.18231.2 0.00185 16-Aug K.GIFLGDQWR.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1090.556 2.75 41608 18231 2 1090.557513 546.2853 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3548.1 - 9.60E+06 - - - 1.4066 - 1.492 0.437 - 225.3 1 2 0 0.0015 9 0 0 0 9.16E+07 3.34E+07 - - - 3.4258 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.18234.18234.2 0.00198 16-Aug K.GIFLGDQWR[166.11].D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1100.5642 2.73 41611 18234 2 1100.56784 551.2894 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3548.3 - 4.43E+06 - - - 3.2629 - 1.709 0.435 - 209.7 1 2 0 0.0036 9 0 0 0 9.08E+07 3.33E+07 - - - 3.8032 0.999 230117_WJC_METTL3_WT_vs_EV_F05.18235.18235.2 0.00162 18-Oct R.YLYTLVITDK[136.11].E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1235.6893 1.49 41612 18235 2 1235.693253 618.8519 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3548.4 - 1.84E+06 - - - 3.2063 - 1.91 0.326 - 233.8 1 2 0 0.004 10 0 0 0 6.94E+08 4.65E+08 - - - 3.2539 1 230117_WJC_METTL3_WT_vs_EV_F05.18236.18236.2 0.00329 14/22 K.IPGIIIAASAVR[166.11].A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1189.7422 2.46 41613 18236 2 1189.746168 595.8784 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3548.6 - 1.67E+06 - - - 3.3242 - 2.603 0.46 - 772.1 1 2 0 0.004 12 0 0 0 4.83E+07 1.96E+07 - - - 4.9545 0.9907 230117_WJC_METTL3_WT_vs_EV_F05.18237.18237.2 1.5 12-Jun K.MIADFLR[166.11].E "sp|Q96R72|OR4K3_HUMAN,sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 4 874.461 4.54 41614 18237 2 874.463787 438.2378 Olfactory receptor 4K3 OS=Homo sapiens OX=9606 GN=OR4K3 PE=3 SV=3 5.59 3548.7 - 1.49E+06 - - - 3.1539 - 1.336 0.146 - 146.7 1 2 0 0.0028 7 0 0 0 4.62E+07 1.02E+07 - - - 1.0364 0.9619 230117_WJC_METTL3_WT_vs_EV_F05.18239.18239.2 0.000373 13/22 H.IISELILTAQER.D sp|Q96I24|FUBP3_HUMAN 1 1384.7926 1.56 41616 18239 2 1384.796805 693.4036 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3548.9 - 841950 - - - 3.051 - 2.451 0.413 - 402.2 1 1 0 0.0042 12 0 0 0 7.10E+06 4.55E+06 - - - 4.4489 1 230117_WJC_METTL3_WT_vs_EV_F05.18240.18240.2 3.16E-05 16-Nov K.YMAEALLLR.A sp|O94826|TOM70_HUMAN 1 1078.5845 1.25 41617 18240 2 1078.588376 540.2995 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 6 3549 - 839563 - - - 3.5917 - 2.251 0.493 - 411.8 1 2 0 0.0039 9 0 0 0 6.09E+06 4.86E+06 - - - 5.0284 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.18241.18241.2 0.304 12-Aug R.YDLWNLK[136.11].Y sp|Q9ULW3|ABT1_HUMAN 1 958.5004 0.76 41618 18241 2 958.503759 480.2575 Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1 5.83 3549.2 - 822333 - - - 3.5378 - 1.542 0.261 - 202.2 1 2 0 0.0034 7 0 0 0 6.95E+06 9.12E+06 - - - 2.3399 0.9962 230117_WJC_METTL3_WT_vs_EV_F05.18242.18242.2 1.08 12-Jul R.YDLWNLK.Y sp|Q9ULW3|ABT1_HUMAN 1 950.4862 0.71 41619 18242 2 950.488718 476.2504 Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1 5.83 3549.3 - 754946 - - - 2.6828 - 1.305 0.221 - 158.9 1 2 0 0.0026 7 0 0 0 6.95E+06 9.81E+06 - - - 1.516 0.9013 230117_WJC_METTL3_WT_vs_EV_F05.18243.18243.2 0.00737 20-Oct R.LLDLVVQPVPR.P sp|Q8WYP5|ELYS_HUMAN 1 1247.7602 1.63 41620 18243 2 1247.765459 624.8874 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.84 3549.4 - 463751 - - - 4.2484 - 1.995 0.407 - 342.5 1 1 0 0.0053 11 0 0 0 8.79E+06 5.39E+06 - - - 3.9138 0.999 230117_WJC_METTL3_WT_vs_EV_F05.18244.18244.2 0.00136 22-Aug K.VLETVGVFEVPK[136.11].Q "sp|Q9Y2S7|PDIP2_HUMAN,tr|B4DEM9|B4DEM9_HUMAN" 2 1323.753 6.57 41621 18244 2 1323.756689 662.8838 Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1 4.53 3549.5 - 396232 - - - 2.8215 - 1.554 0.368 - 75.7 1 2 0 0.0037 12 0 0 0 1.40E+07 2.13E+06 - - - 2.9178 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.18245.18245.2 0.048 14-Jul K.IGGIFAFK.V "sp|P22307|SCP2_HUMAN,tr|H0YF61|H0YF61_HUMAN" 2 851.4905 1.52 41622 18245 2 851.489882 426.7525 Sterol carrier protein 2 OS=Homo sapiens OX=9606 GN=SCP2 PE=1 SV=2 8.75 3549.7 - 288611 - - - -0.7551 - 1.425 0.286 - 85.9 1 2 0 -0.0006 8 0 0 0 3.51E+06 2.31E+06 - - - 2.2214 0.9446 230117_WJC_METTL3_WT_vs_EV_F05.18254.18254.2 2.11 16-Aug R.FLSGLELVK.Q "sp|Q96S44|PRPK_HUMAN,tr|Q5JZ02|Q5JZ02_HUMAN" 2 1004.5906 1.25 41629 18254 2 1004.593025 503.3026 EKC\KEOPS complex subunit TP53RK OS=Homo sapiens OX=9606 GN=TP53RK PE=1 SV=2 6 3550.6 - 2.04E+06 - - - 2.3811 - 1.142 0.01 - 143.9 1 2 0 0.0024 9 0 0 0 2.64E+07 2.11E+07 - - - -0.5017 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.18255.18255.2 0.0198 14-Jul K.LWGVIDVK.R "sp|Q9UHD1|CHRD1_HUMAN,tr|E9PHZ2|E9PHZ2_HUMAN" 2 928.5382 2.12 41630 18255 2 928.539122 465.2764 Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2 5.84 3550.7 - 1.37E+06 - - - 0.9897 - 1.426 0.277 - 129.5 1 2 0 0.0009 8 0 0 0 1.60E+07 7.55E+06 - - - 2.1569 1 230117_WJC_METTL3_WT_vs_EV_F05.18256.18256.2 1.19E-06 22-Dec K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 155.65 41631 18256 2 1382.684021 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3550.8 - 1.35E+06 - - - 0.7167 - 2.338 0.513 - 410.3 1 2 0 0.001 12 0 0 0 1.27E+07 8.16E+04 - - - 5.0643 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.18259.18259.2 1.24 16-Sep R.LALILC[160.03]VTK.A sp|P31944|CASPE_HUMAN 1 1029.6256 999 41634 18259 2 1029.62708 515.8201 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 8.22 3551.1 - 641403 - - - 1.3995 - 1.873 0.123 - 94.1 2 2 0 0.0014 9 0 0 0 6.21E+06 0.00E+00 - - - 1.6301 0.9743 230117_WJC_METTL3_WT_vs_EV_F05.18260.18260.2 0.00538 20-Dec R.LLDLVVQPVPR[166.11].P sp|Q8WYP5|ELYS_HUMAN 1 1257.7684 1.63 41635 18260 2 1257.770365 629.8915 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.84 3551.2 - 592041 - - - 1.54 - 2.337 0.349 - 696.6 1 1 0 0.0019 11 0 0 0 8.79E+06 5.39E+06 - - - 3.9145 1 230117_WJC_METTL3_WT_vs_EV_F05.18261.18261.2 1.14E-08 26-Dec K.FYGPEGPYGVFAGR.D sp|O00264|PGRC1_HUMAN 1 1515.7147 1.42 41636 18261 2 1515.717278 758.8646 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3551.4 - 591709 - - - 1.7246 - 2.461 0.655 - 524.2 1 2 0 0.0026 14 0 0 0 3.06E+07 2.16E+07 - - - 6.1379 1 230117_WJC_METTL3_WT_vs_EV_F05.18263.18263.2 1.54E-10 14/26 K.FYGPEGPYGVFAGR[166.11].D sp|O00264|PGRC1_HUMAN 1 1525.7229 1.42 41638 18263 2 1525.72408 763.8687 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3551.6 - 440625 - - - 0.7511 - 2.436 0.664 - 761.2 1 2 0 0.0011 14 0 0 0 3.06E+07 2.16E+07 - - - 6.1793 0.9592 230117_WJC_METTL3_WT_vs_EV_F05.18264.18264.2 0.429 14-Aug K.DLYSALIK.L sp|O75844|FACE1_HUMAN 1 921.5171 1.2 41639 18264 2 921.520798 461.7658 CAAX prenyl protease 1 homolog OS=Homo sapiens OX=9606 GN=ZMPSTE24 PE=1 SV=2 5.83 3551.8 - 436258 - - - 3.9761 - 1.022 0.167 - 182.8 1 2 0 0.0037 8 0 0 0 2.37E+07 1.98E+07 - - - 0.3389 0.9948 230117_WJC_METTL3_WT_vs_EV_F05.18266.18266.2 0.0415 20-Sep K.VMVTNVTSLLK.T "sp|Q9Y4G6|TLN2_HUMAN,sp|Q9Y490|TLN1_HUMAN,tr|A0A1B0GVU7|A0A1B0GVU7_HUMAN,tr|H0YMT1|H0YMT1_HUMAN" 4 1203.6897 0.27 41641 18266 2 1203.692572 602.8521 Talin-2 OS=Homo sapiens OX=9606 GN=TLN2 PE=1 SV=4 8.72 3552 - 377171 - - - 2.3902 - 1.261 0.201 - 149.3 1 2 0 0.0029 11 0 0 0 4.11E+06 1.52E+07 - - - 1.152 0.996 230117_WJC_METTL3_WT_vs_EV_F05.18267.18267.2 0.608 18-Jul K.LWTMPISSVR[166.11].F "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1198.6408 2.16 41642 18267 2 1198.643689 600.3277 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3552.1 - 372955 - - - 2.4227 - 1.465 0.172 - 149.7 1 2 0 0.0029 10 0 0 0 6.21E+06 2.87E+06 - - - 1.3764 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.18268.18268.2 0.11 20-Sep K.GLLPTPDEFPR.F sp|Q9C0J8|WDR33_HUMAN 1 1240.6452 2.69 41643 18268 2 1240.648142 621.3299 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 4.37 3552.2 - 838975 - - - 2.381 - 1.094 0.275 - 121.4 1 2 0 0.003 11 0 0 0 2.38E+06 8.86E+05 - - - 1.3143 0.9154 230117_WJC_METTL3_WT_vs_EV_F05.18275.18275.2 0.258 18-Oct S.GVAVSDGVIK.V "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PS23|E9PS23_HUMAN" 4 943.5338 2.07 41648 18275 2 943.53587 472.7742 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 5.84 3552.9 - 1.21E+06 - - - 2.1451 - 1.723 0.248 - 218.6 1 1 0 0.002 10 0 0 0 4.75E+08 2.29E+08 - - - 2.3907 0.9859 230117_WJC_METTL3_WT_vs_EV_F05.18278.18278.2 0.0129 20-Nov R.ILDVGFEEELK[136.11].Q "sp|Q9NVP1|DDX18_HUMAN,tr|H7C452|H7C452_HUMAN" 2 1298.6849 1.27 41651 18278 2 1298.681457 650.3497 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 4 3553.3 - 628019 - - - -2.6773 - 1.773 0.165 - 392.8 1 2 0 -0.0035 11 0 0 0 8.47E+06 6.69E+06 - - - 1.8078 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.18279.18279.2 0.00119 14-Sep R.GFGFVQFK[136.11].N "sp|Q9NW13|RBM28_HUMAN,tr|C9JE21|C9JE21_HUMAN" 2 936.4949 0.77 41652 18279 2 936.496691 469.2547 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 8.75 3553.4 - 615862 - - - 1.9242 - 1.581 0.325 - 247.8 1 2 0 0.0018 8 0 0 0 1.19E+07 1.55E+07 - - - 2.8224 0.9661 230117_WJC_METTL3_WT_vs_EV_F05.18281.18281.2 0.0282 13/22 L.PLIPIVVEQTGR.G sp|Q16740|CLPP_HUMAN 1 1320.7765 1.54 41654 18281 2 1320.779904 661.3955 "ATP-dependent Clp protease proteolytic subunit, mitochondrial OS=Homo sapiens OX=9606 GN=CLPP PE=1 SV=1" 6.43 3553.7 - 593892 - - - 2.55 - 2.282 0.382 - 433.6 1 1 0 0.0034 12 0 0 0 5.57E+06 3.63E+06 - - - 4.0322 1 230117_WJC_METTL3_WT_vs_EV_F05.18282.18282.2 0.000466 13/18 K.IGSDVELLLR.T sp|Q5U5X0|LYRM7_HUMAN 1 1113.6394 2.41 41655 18282 2 1113.643661 557.827 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 4.37 3553.8 - 531211 - - - 3.8495 - 2.739 0.45 - 451.3 1 2 0 0.0043 10 0 0 0 4.54E+07 1.89E+07 - - - 5.1759 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.18284.18284.2 0.00305 20-Oct K.AVLWVSADGLR[166.11].V "sp|P49757|NUMB_HUMAN,tr|G3V3R1|G3V3R1_HUMAN,tr|G3V3M5|G3V3M5_HUMAN" 3 1195.6589 1.46 41657 18284 2 1195.663589 598.8367 Protein numb homolog OS=Homo sapiens OX=9606 GN=NUMB PE=1 SV=2 5.88 3554.1 - 427715 - - - 3.9409 - 2.145 0.385 - 278.6 1 2 0 0.0047 11 0 0 0 4.15E+06 2.85E+06 - - - 3.9476 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18286.18286.2 0.001 22-Oct K.IVAISC[160.03]AADILK.A "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|F6XAQ5|F6XAQ5_HUMAN" 4 1272.7112 1.27 41659 18286 2 1272.713981 637.3629 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.83 3554.3 - 254538 - - - 2.2173 - 1.774 0.379 - 293.1 1 2 0 0.0028 12 0 0 0 3.34E+06 2.62E+06 - - - 3.3477 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.18288.18288.2 0.116 12-Jun K.YLLWYC[160.03]K.A "sp|Q14202|ZMYM3_HUMAN,tr|A6NHB5|A6NHB5_HUMAN,tr|A6NHN7|A6NHN7_HUMAN" 3 1044.5103 999 41661 18288 2 1044.512508 523.2624 Zinc finger MYM-type protein 3 OS=Homo sapiens OX=9606 GN=ZMYM3 PE=1 SV=2 8.18 3554.6 - 141432 - - - 2.1388 - 1.186 0.293 - 96.4 1 2 0 0.0022 7 0 0 0 9.47E+05 0.00E+00 - - - 1.7449 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.18289.18289.2 0.00338 22-Jun R.LVPVSFEDPEFK.S tr|F5GXE4|F5GXE4_HUMAN 1 1405.7129 10.28 41662 18289 2 1405.71498 703.8637 Arginyl-tRNA--protein transferase 1 OS=Homo sapiens OX=9606 GN=ATE1 PE=1 SV=1 4.14 3554.7 - 117265 - - - 1.4562 - 1.494 0.363 - 56.4 1 2 0 0.002 12 0 0 0 1.92E+06 1.87E+05 - - - 2.7778 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.18293.18293.2 0.0291 16-Jul R.ILFLDPSGK[136.11].V sp|O95881|TXD12_HUMAN 1 996.5735 1.1 41664 18293 2 996.575276 499.294 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3555.2 - 5.77E+06 - - - 1.749 - 1.59 0.297 - 121.7 1 2 0 0.0017 9 0 0 0 5.60E+08 5.09E+08 - - - 2.5757 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18294.18294.2 8.97E-05 16-Oct R.ILFLDPSGK.V sp|O95881|TXD12_HUMAN 1 988.5593 1.1 41665 18294 2 988.561785 495.2869 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3555.2 - 5.78E+06 - - - 2.4804 - 1.897 0.441 - 298.8 1 2 0 0.0025 9 0 0 0 5.60E+08 5.11E+08 - - - 4.1498 1 230117_WJC_METTL3_WT_vs_EV_F05.18295.18295.2 0.000221 13/18 R.IPLNPYLNLH.S "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 1192.6604 - 41666 18295 2 1192.65951 597.3375 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.74 3555.3 - 3.28E+06 - - - -0.7831 - 2.383 0.494 - 594.9 1 1 0 -0.0009 10 0 0 0 - - - - - 5.1132 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18297.18297.2 8.72E-05 20-Aug K.FGEPVLAGFAR[166.11].S sp|O15067|PUR4_HUMAN 1 1172.6218 3.76 41668 18297 2 1172.622953 587.3182 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 6 3555.6 - 926997 - - - 1.014 - 1.73 0.327 - 187.5 1 2 0 0.0012 11 0 0 0 2.87E+07 7.63E+06 - - - 2.9386 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18308.18308.2 0.000417 20-Nov R.MLDMGFEPQIR[166.11].R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1345.6398 1.27 41677 18308 2 1345.640239 673.8272 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3556.9 - 1.83E+06 - - - 0.3277 - 2.157 0.468 - 478.9 1 2 0 0.0004 11 0 0 0 1.21E+08 9.51E+07 - - - 4.5771 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.18309.18309.2 0.137 18-Aug K.GLVASLISVK[136.11].D sp|O95347|SMC2_HUMAN 1 993.6314 1.07 41678 18309 2 993.631726 497.823 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 8.75 3557 - 6.42E+06 - - - 0.3462 - 2.224 0.137 - 221.8 2 2 0 0.0003 10 0 0 0 2.05E+07 1.92E+07 - - - 2.1494 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.18313.18313.2 0.000329 20-Sep R.ILMLGLDAAGK[136.11].T sp|P62330|ARF6_HUMAN 1 1108.6406 0.56 41682 18313 2 1108.644522 555.3276 ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2 5.84 3557.3 - 881496 - - - 3.5674 - 1.758 0.435 - 148.8 1 2 0 0.004 11 0 0 0 2.21E+06 3.97E+06 - - - 3.7789 0.999 230117_WJC_METTL3_WT_vs_EV_F05.18317.18317.3 0.0144 Nov-48 K.NILFVITK[136.11]PDVYK[136.11].S "sp|E9PAV3|NACAM_HUMAN,sp|Q9BZK3|NACP4_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|F8VNW4|F8VNW4_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN,tr|F8VZ58|F8VZ58_HUMAN" 10 1564.92 -1 41686 18317 3 1564.920486 522.6473 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 8.5 3557.7 - 332882 - - - 0.3323 - 1.77 0.286 - 99.4 1 2 0 0.0005 13 0 0 0 0.00E+00 0.00E+00 - - - 3.2766 0.9615 230117_WJC_METTL3_WT_vs_EV_F05.18321.18321.2 0.224 14-Jun R.GFGFVQFK.N "sp|Q9NW13|RBM28_HUMAN,tr|C9JE21|C9JE21_HUMAN" 2 928.4807 0.74 41688 18321 2 928.481929 465.2476 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 8.75 3558.2 - 1.18E+06 - - - 1.3355 - 1.111 0.029 - 90.3 1 2 0 0.0012 8 0 0 0 1.24E+07 1.67E+07 - - - -0.4277 1 230117_WJC_METTL3_WT_vs_EV_F05.18322.18322.2 4.04E-05 20-Nov R.MLDMGFEPQIR.R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1335.6315 1.27 41689 18322 2 1335.633003 668.823 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3558.3 - 1.38E+06 - - - 1.1043 - 2.129 0.541 - 482.6 1 2 0 0.0015 11 0 0 0 1.21E+08 9.50E+07 - - - 5.0806 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.18323.18323.2 0.205 14-Jul R.EMVLEIIR[166.11].E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1011.5662 1.37 41690 18323 2 1011.566901 506.7904 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3558.3 - 1.65E+06 - - - 0.6702 - 1.602 0.201 - 310.4 1 2 0 0.0007 8 0 0 0 3.50E+08 2.55E+08 - - - 1.9467 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.18329.18329.2 0.11 16-Sep K.ILLITEDLK.N sp|Q08752|PPID_HUMAN 1 1056.6431 2.8 41696 18329 2 1056.644693 529.3288 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 4.37 3559 - 417886 - - - 1.5426 - 1.841 0.182 - 222.5 1 2 0 0.0016 9 0 0 0 2.92E+07 1.04E+07 - - - 2.1504 1 230117_WJC_METTL3_WT_vs_EV_F05.18330.18330.2 8.54E-06 16-Nov K.LYMVLITTK.N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 3 1080.6253 1.48 41697 18330 2 1080.627106 541.3199 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 8.59 3559.2 - 338565 - - - 1.6676 - 2.026 0.504 - 389.2 1 2 0 0.0018 9 0 0 0 1.57E+07 1.06E+07 - - - 4.8057 0.9969 230117_WJC_METTL3_WT_vs_EV_F05.18341.18341.2 0.207 14-Jul R.EMVLEIIR.E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1001.558 1.36 41706 18341 2 1001.561529 501.7863 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3560.7 - 2.11E+07 - - - 3.5704 - 1.692 0.217 - 301.8 1 2 0 0.0036 8 0 0 0 3.44E+08 2.53E+08 - - - 2.2288 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.18342.18342.2 0.0835 14-Sep K.VALLLLEK.E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 897.5899 1.42 41707 18342 2 897.593239 449.8022 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3560.7 - 2.17E+06 - - - 3.7144 - 1.915 0.238 - 300.9 1 2 0 0.0033 8 0 0 0 1.84E+07 1.29E+07 - - - 2.7573 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18343.18343.2 0.00269 16-Aug K.LEVDIPLVK.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1024.6168 2.8 41708 18343 2 1024.618145 513.3157 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3560.8 - 2.72E+06 - - - 1.2658 - 1.818 0.384 - 213.7 1 2 0 0.0013 9 0 0 0 1.49E+08 5.33E+07 - - - 3.6061 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.18344.18344.2 0.295 16-Sep K.LSDGVAVLK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 900.528 3.35 41709 18344 2 900.529951 451.2713 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 3560.8 - 2.21E+06 - - - 2.1299 - 1.709 0.23 - 155.2 1 2 0 0.0019 9 0 0 0 2.38E+07 7.11E+06 - - - 2.2896 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18345.18345.2 0.000703 22-Oct K.GLTPSQIGVILR[166.11].D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1262.7586 0.89 41710 18345 2 1262.761091 632.3866 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3560.9 - 1.87E+06 - - - 1.979 - 2.294 0.349 - 408.9 1 2 0 0.0025 12 0 0 0 5.39E+07 6.09E+07 - - - 3.8026 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.18346.18346.2 0.0902 12-Jun R.EIFITFR.V sp|Q96EY1|DNJA3_HUMAN 1 924.5069 1.74 41711 18346 2 924.507908 463.2607 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.1 3561 - 1.74E+06 - - - 1.0871 - 1.358 0.251 - 140.5 1 2 0 0.001 7 0 0 0 2.79E+07 1.60E+07 - - - 1.8642 0.9837 230117_WJC_METTL3_WT_vs_EV_F05.18347.18347.2 0.161 12-Jun R.EIFITFR[166.11].V sp|Q96EY1|DNJA3_HUMAN 1 934.5152 1.73 41712 18347 2 934.512843 468.2649 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.1 3561.1 - 1.68E+06 - - - -2.4933 - 1.328 0.222 - 123.9 1 2 0 -0.0023 7 0 0 0 2.77E+07 1.60E+07 - - - 1.5788 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18348.18348.2 5.88E-05 16-Oct K.LEVDIPLVK[136.11].S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1032.631 2.76 41713 18348 2 1032.632512 517.3228 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3561.1 - 1.47E+06 - - - 1.4177 - 1.999 0.439 - 256.9 1 2 0 0.0015 9 0 0 0 1.46E+08 5.29E+07 - - - 4.2869 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18349.18349.2 7.24E-06 22-Nov K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 0.89 41714 18349 2 1252.752347 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3561.2 - 1.38E+06 - - - 1.6164 - 2.344 0.317 - 498.3 1 2 0 0.002 12 0 0 0 5.39E+07 6.08E+07 - - - 3.6231 0.9964 230117_WJC_METTL3_WT_vs_EV_F05.18351.18351.2 0.0245 20-Sep R.LPPEFSPVIIK[136.11].E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1246.7417 0.63 41716 18351 2 1246.744467 624.3781 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6 3561.5 - 598595 - - - 2.2507 - 1.454 0.181 - 203.1 1 2 0 0.0028 11 0 0 0 7.63E+06 1.22E+07 - - - 1.3896 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.18355.18355.2 0.00081 14-Aug K.VALLLLEK[136.11].E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 905.6041 1.43 41719 18355 2 905.605358 453.8093 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3562 - 2.13E+06 - - - 1.3836 - 2.109 0.099 - 196.2 1 2 0 0.0013 8 0 0 0 1.85E+07 1.29E+07 - - - 2.0224 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18357.18357.2 0.00838 16-Sep R.LYSVSYLLK[136.11].D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1092.631 0.65 41721 18357 2 1092.633047 547.3228 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.5 3562.2 - 5.47E+06 - - - 1.8295 - 1.855 0.385 - 199.2 1 2 0 0.002 9 0 0 0 3.72E+07 5.69E+07 - - - 3.6716 0.8511 230117_WJC_METTL3_WT_vs_EV_F05.18358.18358.2 0.0278 14-Aug V.ILSILLSK.A "sp|Q6UXB4|CLC4G_HUMAN,sp|Q02040|AK17A_HUMAN,tr|A0A7I2V4C7|A0A7I2V4C7_HUMAN,tr|M0R277|M0R277_HUMAN,tr|A0A7I2V4U5|A0A7I2V4U5_HUMAN" 5 885.5899 1.06 41722 18358 2 885.591879 443.8022 C-type lectin domain family 4 member G OS=Homo sapiens OX=9606 GN=CLEC4G PE=1 SV=1 8.75 3562.3 - 2.15E+06 - - - 2.229 - 1.638 0.173 - 174.5 1 1 0 0.002 8 0 0 0 1.06E+07 1.00E+07 - - - 1.8065 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.18359.18359.2 0.0622 16-Aug K.ILLITEDLK[136.11].N sp|Q08752|PPID_HUMAN 1 1064.6573 2.8 41723 18359 2 1064.659143 533.3359 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 4.37 3562.4 - 1.69E+06 - - - 1.7658 - 1.778 0.251 - 171.8 1 2 0 0.0019 9 0 0 0 2.92E+07 1.04E+07 - - - 2.5592 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.18360.18360.2 0.0252 16-Oct R.SLIAEVLVK.L sp|O95969|SG1D2_HUMAN 1 970.6063 417.85 41724 18360 2 970.608447 486.3104 Secretoglobin family 1D member 2 OS=Homo sapiens OX=9606 GN=SCGB1D2 PE=2 SV=1 5.72 3562.5 - 1.32E+06 - - - 2.2295 - 1.553 0.322 - 270.5 1 2 0 0.0022 9 0 0 0 2.02E+07 4.85E+04 - - - 2.6921 1 230117_WJC_METTL3_WT_vs_EV_F05.18365.18365.2 3.69E-09 14/22 K.AFAVGVQQVLLK.V sp|O95373|IPO7_HUMAN 1 1271.7602 1.77 41727 18365 2 1271.762804 636.8874 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 8.8 3563.1 - 384521 - - - 2.0806 - 2.793 0.556 - 648.2 1 2 0 0.0026 12 0 0 0 1.70E+07 9.60E+06 - - - 5.8493 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18366.18366.2 0.00273 18-Jul K.VFLSGMPELR.L "sp|Q9Y6Q5|AP1M2_HUMAN,sp|Q9BXS5|AP1M1_HUMAN,tr|E7ENJ6|E7ENJ6_HUMAN,tr|K7EJL1|K7EJL1_HUMAN,tr|K7EJJ1|K7EJJ1_HUMAN,tr|K7EMG5|K7EMG5_HUMAN,tr|K7EPR4|K7EPR4_HUMAN" 7 1147.606 1.19 41728 18366 2 1147.607259 574.8103 AP-1 complex subunit mu-2 OS=Homo sapiens OX=9606 GN=AP1M2 PE=1 SV=4 5.97 3563.3 - 338052 - - - 1.1276 - 1.739 0.338 - 151.4 1 2 0 0.0013 10 0 0 0 7.30E+06 6.14E+06 - - - 3.0815 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18368.18368.2 0.00187 20-Oct R.ALDTMNFDVIK[136.11].G "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 20 1273.6468 1.07 41730 18368 2 1273.648443 637.8307 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.21 3563.5 - 384521 - - - 1.3104 - 1.727 0.389 - 235.9 1 2 0 0.0017 11 0 0 0 7.30E+06 6.82E+06 - - - 3.3917 1 230117_WJC_METTL3_WT_vs_EV_F05.18372.18372.2 8.01E-07 22-Nov K.AFAVGVQQVLLK[136.11].V sp|O95373|IPO7_HUMAN 1 1279.7744 1.77 41734 18372 2 1279.7806 640.8945 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 8.8 3564 - 176118 - - - 4.8774 - 2.473 0.577 - 389.2 1 2 0 0.0062 12 0 0 0 1.70E+07 9.60E+06 - - - 5.6831 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.18375.18375.2 0.0932 12-Jun R.DLFALAR[166.11].K sp|Q9Y4W6|AFG32_HUMAN 1 814.4577 1.27 41736 18375 2 814.458609 408.2361 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.84 3564.4 - 495733 - - - 1.1676 - 1.28 0.193 - 175.6 1 2 0 0.001 7 0 0 0 7.81E+06 6.15E+06 - - - 1.2484 1 230117_WJC_METTL3_WT_vs_EV_F05.18377.18377.2 0.00496 14/22 R.MGLAISLVATEK.E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 1231.6846 1.49 41737 18377 2 1231.686195 616.8496 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.75 3564.6 - 2.14E+06 - - - 1.2869 - 2.771 0.489 - 719.9 1 2 0 0.0016 12 0 0 0 1.97E+07 1.32E+07 - - - 5.334 1 230117_WJC_METTL3_WT_vs_EV_F05.18378.18378.2 1.43E-05 22-Oct R.MGLAISLVATEK[136.11].E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 1239.6988 1.45 41738 18378 2 1239.697084 620.8567 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.75 3564.7 - 1.51E+06 - - - -1.3923 - 2.303 0.501 - 255.5 1 2 0 -0.0017 12 0 0 0 1.92E+07 1.32E+07 - - - 4.9358 0.9822 230117_WJC_METTL3_WT_vs_EV_F05.18379.18379.2 0.0809 14-Aug K.SYYLGLLR.S "sp|Q96LB3|IFT74_HUMAN,tr|E5RJK3|E5RJK3_HUMAN,tr|E5RGX6|E5RGX6_HUMAN,tr|A0A3B3IT46|A0A3B3IT46_HUMAN,tr|E5RIF0|E5RIF0_HUMAN,tr|E5RH29|E5RH29_HUMAN" 6 983.544 2.14 41739 18379 2 983.550127 492.7793 Intraflagellar transport protein 74 homolog OS=Homo sapiens OX=9606 GN=IFT74 PE=1 SV=1 8.31 3564.8 - 1.69E+06 - - - 6.2122 - 1.567 0.252 - 276.3 1 2 0 0.0061 8 0 0 0 1.14E+07 5.32E+06 - - - 2.255 0.999 230117_WJC_METTL3_WT_vs_EV_F05.18380.18380.2 0.139 18-Nov K.ALQEFDLALR[166.11].G "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1184.6429 0.87 41740 18380 2 1184.645143 593.3287 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 4.37 3564.9 - 1.41E+06 - - - 1.8993 - 1.812 0.236 - 421.2 1 2 0 0.0022 10 0 0 0 9.68E+06 1.12E+07 - - - 2.4426 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.18382.18382.2 0.015 12-Aug R.NYLSIFR.K sp|P07384|CAN1_HUMAN 1 911.4865 13.42 41742 18382 2 911.489423 456.7505 Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1 8.75 3565.2 - 1.08E+06 - - - 3.2047 - 1.464 0.243 - 248.2 1 2 0 0.0029 7 0 0 0 1.99E+07 1.48E+06 - - - 2.0426 0.9945 230117_WJC_METTL3_WT_vs_EV_F05.18383.18383.2 0.495 12-Aug R.DLFALAR.K sp|Q9Y4W6|AFG32_HUMAN 1 804.4494 1.24 41743 18383 2 804.450705 403.232 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.84 3565.3 - 1.01E+06 - - - 1.6371 - 1.307 0.14 - 269.3 1 2 0 0.0013 7 0 0 0 8.00E+06 6.43E+06 - - - 0.923 1 230117_WJC_METTL3_WT_vs_EV_F05.18384.18384.2 1.81E-05 18-Oct K.FYALDPSFPR.M sp|Q08J23|NSUN2_HUMAN 1 1211.5975 1.46 41744 18384 2 1211.594254 606.806 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3565.5 - 1.01E+06 - - - -2.6865 - 1.87 0.542 - 349.7 1 2 0 -0.0033 10 0 0 0 9.49E+06 6.51E+06 - - - 4.7904 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.18387.18387.2 0.0199 14-Aug K.NGLDVLFK.V "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 904.5018 1.56 41747 18387 2 904.50424 453.2582 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 5.84 3565.9 - 729565 - - - 2.6777 - 1.332 0.293 - 176.1 1 2 0 0.0024 8 0 0 0 8.15E+06 5.23E+06 - - - 2.069 1 230117_WJC_METTL3_WT_vs_EV_F05.18390.18390.2 4.76E-07 20-Sep K.LVNIYDSMPLR.Y sp|Q9UBQ6|EXTL2_HUMAN 1 1319.6908 0.8 41750 18390 2 1319.6933 660.8527 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 5.84 3566.2 - 279562 - - - 1.9262 - 2.329 0.534 - 346.1 1 2 0 0.0025 11 0 0 0 2.32E+06 2.90E+06 - - - 5.2714 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18391.18391.2 0.00286 16-Sep K.LLQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1118.5748 13.31 41751 18391 2 1118.578051 560.2947 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3566.4 - 168394 - - - 2.8948 - 1.824 0.43 - 244.4 1 2 0 0.0032 9 0 0 0 4.24E+08 3.18E+07 - - - 3.9548 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18395.18395.2 0.00036 18-Oct K.FYALDPSFPR[166.11].M sp|Q08J23|NSUN2_HUMAN 1 1221.6058 1.72 41754 18395 2 1221.608403 611.8102 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3566.9 - 449301 - - - 2.148 - 1.874 0.394 - 335.4 1 2 0 0.0026 10 0 0 0 1.28E+07 7.43E+06 - - - 3.7034 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18396.18396.2 7.29E-05 18-Oct R.VLLMELEEAR.G sp|P12270|TPR_HUMAN 1 1201.6377 1.4 41755 18396 2 1201.639128 601.8261 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3567 - 1.90E+06 - - - 1.2217 - 2.387 0.383 - 451.6 1 2 0 0.0015 10 0 0 0 3.46E+07 2.48E+07 - - - 4.2979 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.18409.18409.2 0.0143 12-Sep K.C[160.03]ALDFFR.Q sp|P51970|NDUA8_HUMAN 1 927.4273 1.45 41766 18409 2 927.431584 464.7209 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3568.5 - 1.41E+06 - - - 4.6483 - 1.719 0.366 - 402.4 1 2 0 0.0043 7 0 0 0 2.08E+07 1.43E+07 - - - 3.4595 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.18411.18411.2 0.0281 12-Sep K.C[160.03]ALDFFR[166.11].Q sp|P51970|NDUA8_HUMAN 1 937.4355 1.45 41768 18411 2 937.439029 469.725 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3568.7 - 1.16E+06 - - - 3.7187 - 1.837 0.371 - 456.1 1 2 0 0.0035 7 0 0 0 2.08E+07 1.43E+07 - - - 3.707 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18412.18412.2 0.0268 16-Sep K.LQDPFSLYR.C sp|P21912|SDHB_HUMAN 1 1137.5819 3.89 41769 18412 2 1137.583718 569.7982 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.84 3568.8 - 673549 - - - 1.6342 - 1.982 0.286 - 172.6 2 2 0 0.0019 9 0 0 0 5.24E+07 1.35E+07 - - - 2.9975 0.994 230117_WJC_METTL3_WT_vs_EV_F05.18413.18413.2 0.0164 12-Jul R.TIFSYFK.G sp|Q9UJV9|DDX41_HUMAN 1 904.4695 1.2 41770 18413 2 904.472001 453.242 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 8.26 3569 - 642804 - - - 2.8149 - 1.234 0.204 - 153.2 1 2 0 0.0025 7 0 0 0 3.76E+07 3.15E+07 - - - 1.2132 1 230117_WJC_METTL3_WT_vs_EV_F05.18414.18414.2 0.000295 18-Nov K.TLVQILTEPR[166.11].N sp|O76031|CLPX_HUMAN 1 1178.6898 2.23 41771 18414 2 1178.694949 590.3522 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3569.1 - 534846 - - - 4.3319 - 2.331 0.444 - 543.8 1 2 0 0.0051 10 0 0 0 2.28E+07 1.03E+07 - - - 4.6811 0.9798 230117_WJC_METTL3_WT_vs_EV_F05.18417.18417.2 0.00251 16-Oct R.ELGELIPLR[166.11].Q "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1048.6156 1.08 41774 18417 2 1048.625447 525.3151 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.53 3569.5 - 801802 - - - 9.3752 - 1.893 0.389 - 325.9 1 2 0 0.0098 9 0 0 0 1.89E+07 1.75E+07 - - - 3.7573 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.18424.18424.2 0.192 18-May K.FLALYLHGAA.- "sp|Q9BZE1|RM37_HUMAN,tr|A6NHR2|A6NHR2_HUMAN" 2 1074.5862 - 41779 18424 2 1074.587422 538.3004 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 6.74 3570.4 - 1.60E+06 - - - 1.1223 - 1.185 0.301 - 46.7 2 2 0 0.0012 10 0 0 0 - - - - - 1.6031 0.9877 230117_WJC_METTL3_WT_vs_EV_F05.18433.18433.2 0.0601 16-Sep R.GFIVESVLR.N sp|Q86UQ0|ZN589_HUMAN 1 1018.5811 3.12 41788 18433 2 1018.587484 510.2978 Zinc finger protein 589 OS=Homo sapiens OX=9606 GN=ZNF589 PE=1 SV=1 6 3571.5 - 295479 - - - 6.2371 - 2.084 0.205 - 257 1 2 0 0.0064 9 0 0 0 5.58E+06 1.79E+06 - - - 2.6775 0.999 230117_WJC_METTL3_WT_vs_EV_F05.18434.18434.2 0.0308 20-Sep R.IFVFEPPPGVK.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 1228.6856 1.59 41789 18434 2 1228.687875 615.3501 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3571.6 - 277690 - - - 1.8548 - 1.633 0.285 - 207.1 1 2 0 0.0023 11 0 0 0 4.24E+08 2.67E+08 - - - 2.472 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.18442.18442.2 0.0193 14-Jun R.LLLEEIYR[166.11].G "sp|Q9Y2P8|RCL1_HUMAN,tr|Q5VZU2|Q5VZU2_HUMAN,tr|Q5VZU3|Q5VZU3_HUMAN" 3 1057.6047 0.63 41796 18442 2 1057.607127 529.8096 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 4.53 3572.4 - 1.63E+06 - - - 2.2787 - 1.418 0.277 - 115 1 2 0 0.0024 8 0 0 0 1.85E+07 2.93E+07 - - - 2.1395 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18444.18444.2 0.00659 16-Aug R.ELGELIPLR.Q "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1038.6073 1.08 41798 18444 2 1038.608726 520.3109 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.53 3572.5 - 1.51E+06 - - - 1.3287 - 1.665 0.352 - 279.5 1 2 0 0.0014 9 0 0 0 1.89E+07 1.75E+07 - - - 3.1154 1 230117_WJC_METTL3_WT_vs_EV_F05.18446.18446.2 0.00263 18-Nov K.TLVQILTEPR.N sp|O76031|CLPX_HUMAN 1 1168.6816 2.21 41800 18446 2 1168.684048 585.3481 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3572.6 - 1.14E+06 - - - 2.1178 - 2.383 0.438 - 581.3 1 2 0 0.0025 10 0 0 0 2.27E+07 1.03E+07 - - - 4.6991 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.18447.18447.2 0.0578 14-Jul K.SIGDIFLK[136.11].Y "sp|Q9H8V3|ECT2_HUMAN,tr|H7C3G1|H7C3G1_HUMAN" 2 899.5208 0.98 41801 18447 2 899.521948 450.7677 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 5.55 3572.7 - 966211 - - - 1.3107 - 1.305 0.229 - 130.2 1 2 0 0.0012 8 0 0 0 1.07E+07 1.10E+07 - - - 1.5349 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18448.18448.2 0.0308 16-Oct K.LALFQAIGK.E "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 959.5804 1.88 41802 18448 2 959.582053 480.7975 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 8.75 3572.8 - 909432 - - - 1.7195 - 2.061 0.316 - 248.8 1 2 0 0.0016 9 0 0 0 6.30E+06 3.36E+06 - - - 3.4667 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18450.18450.2 0.000107 18-Aug K.LGMNLMNELK.Q "sp|Q16890|TPD53_HUMAN,tr|E9PNK6|E9PNK6_HUMAN,tr|E9PNQ9|E9PNQ9_HUMAN,tr|E9PPQ1|E9PPQ1_HUMAN,tr|J3KNE7|J3KNE7_HUMAN" 5 1161.5886 2.52 41804 18450 2 1161.59045 581.8016 Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1 6 3572.9 - 639473 - - - 1.5918 - 1.758 0.4 - 150 1 2 0 0.0019 10 0 0 0 6.83E+06 2.71E+06 - - - 3.5696 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.18452.18452.2 2.04E-06 24-Sep K.LFPDTPLALDANK[136.11].K sp|Q12906|ILF3_HUMAN 1 1421.7646 0.54 41806 18452 2 1421.770912 711.8896 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3573.1 - 363575 - - - 4.4529 - 1.824 0.529 - 229.1 1 2 0 0.0063 13 0 0 0 8.24E+06 1.53E+07 - - - 4.4888 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18456.18456.2 0.0101 16-Nov K.LLQDFFNGR.D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1108.5665 13.31 41809 18456 2 1108.568417 555.2905 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3573.6 - 5.07E+07 - - - 1.6905 - 2.051 0.449 - 442.2 1 2 0 0.0019 9 0 0 0 4.24E+08 3.18E+07 - - - 4.4349 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18459.18459.2 0.0032 22-Dec K.YILAATLDNTLK[136.11].L sp|P61964|WDR5_HUMAN 1 1342.7588 1.56 41811 18459 2 1342.761164 672.3867 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 5.83 3573.9 - 583776 - - - 1.7844 - 2.218 0.403 - 365.1 1 2 0 0.0024 12 0 0 0 4.10E+07 2.63E+07 - - - 4.1128 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.18460.18460.2 0.00191 12-Jul R.VWSDFLR.V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 921.4709 2.27 41812 18460 2 921.472098 461.7427 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.81 3574 - 643661 - - - 1.3522 - 1.424 0.276 - 241.8 1 2 0 0.0012 7 0 0 0 1.96E+07 8.61E+06 - - - 2.1991 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.18464.18464.2 0.0884 20-Sep R.LPPEFSPVIIK.E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1238.7275 0.68 41816 18464 2 1238.730854 620.371 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6 3574.5 - 300631 - - - 2.7391 - 1.635 0.194 - 180 1 2 0 0.0034 11 0 0 0 7.63E+06 1.12E+07 - - - 1.8028 0.8923 230117_WJC_METTL3_WT_vs_EV_F05.18465.18465.2 5.44 12-May K.LIPFLEK[136.11].L sp|Q05D32|CTSL2_HUMAN 1 866.5357 1.35 41817 18465 2 866.537078 434.2751 CTD small phosphatase-like protein 2 OS=Homo sapiens OX=9606 GN=CTDSPL2 PE=1 SV=2 6 3574.6 - 207952 - - - 1.6006 - 1.055 0.001 - 57.6 5 2 0 0.0014 7 0 0 0 4.05E+06 3.01E+06 - - - -1.0946 0.998 230117_WJC_METTL3_WT_vs_EV_F05.18470.18470.2 0.000578 13/20 K.LGLENAEALIR[166.11].L sp|P10155|RO60_HUMAN 1 1207.68 2.97 41820 18470 2 1207.685991 604.8473 60 kDa SS-A\Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2 4.53 3575.2 - 194475 - - - 4.955 - 2.212 0.409 - 425.7 1 2 0 0.006 11 0 0 0 3.96E+07 1.33E+07 - - - 4.2077 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.18471.18471.2 0.41 12-Jul R.LFLEFER.K "sp|O43663|PRC1_HUMAN,sp|Q96I25|SPF45_HUMAN,tr|H0YL53|H0YL53_HUMAN" 3 952.5018 2.51 41821 18471 2 952.503589 477.2582 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 3575.2 - 392503 - - - 1.8593 - 1.479 0.168 - 176.7 1 2 0 0.0018 7 0 0 0 2.83E+07 1.13E+07 - - - 1.5214 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.18472.18472.2 0.0756 22-Aug K.LLHSDLAPTLLE.- sp|Q6ZQX7|LIAT1_HUMAN 1 1320.7289 - 41822 18472 2 1320.731296 661.3717 Protein LIAT1 OS=Homo sapiens OX=9606 GN=LIAT1 PE=1 SV=2 4.71 3575.4 - 80430.6 - - - 1.8013 - 1.75 0.225 - 206.7 1 2 0 0.0024 12 0 0 0 - - - - - 2.1745 1 230117_WJC_METTL3_WT_vs_EV_F05.18476.18476.2 8.84E-08 18/28 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 1.41 41824 18476 2 1458.760169 730.386 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3576 - 1.27E+06 - - - 1.8591 - 3.338 0.585 - 1379.3 1 2 0 0.0027 15 0 0 0 9.85E+07 6.98E+07 - - - 6.3244 1 230117_WJC_METTL3_WT_vs_EV_F05.18477.18477.2 2.63E-07 18/28 R.LPAAGVGDMVMATVK[136.11].K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1466.7717 1.41 41825 18477 2 1466.774424 734.3931 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3576.1 - 881659 - - - 1.8865 - 3.473 0.548 - 1183.6 1 2 0 0.0028 15 0 0 0 9.85E+07 6.98E+07 - - - 6.1486 0.973 230117_WJC_METTL3_WT_vs_EV_F05.18478.18478.2 0.282 12-May R.VWSDFLR[166.11].V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 931.4791 2.27 41826 18478 2 931.482297 466.7468 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.81 3576.2 - 667414 - - - 3.4086 - 1.186 0.125 - 84.4 2 2 0 0.0032 7 0 0 0 1.96E+07 8.61E+06 - - - 0.3693 1 230117_WJC_METTL3_WT_vs_EV_F05.18483.18483.2 0.019 20-Oct K.PLVVQVPTFAR.R sp|O00257|CBX4_HUMAN 1 1225.7183 2.6 41831 18483 2 1225.720734 613.8664 E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3 10.18 3576.7 - 466000 - - - 1.9915 - 2.206 0.467 - 416.1 1 1 0 0.0024 11 0 0 0 4.95E+06 1.90E+06 - - - 4.6298 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18484.18484.2 0.021 24-Dec K.LFPDTPLALDANK.K sp|Q12906|ILF3_HUMAN 1 1413.7504 0.63 41832 18484 2 1413.753076 707.8825 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3576.8 - 408921 - - - 1.9063 - 1.98 0.475 - 240.7 1 2 0 0.0027 13 0 0 0 5.20E+06 8.31E+06 - - - 4.3017 1 230117_WJC_METTL3_WT_vs_EV_F05.18490.18490.2 1.34E-06 30-Oct K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 999 41838 18490 2 1789.885581 895.9496 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3577.6 - 105896 - - - 0.5241 - 1.84 0.601 - 231.6 1 2 0 0.0009 16 0 0 0 1.47E+06 0.00E+00 - - - 4.9788 0.9909 230117_WJC_METTL3_WT_vs_EV_F05.18494.18494.2 0.489 18-Jun R.LGLLGLPAPK.N sp|Q99459|CDC5L_HUMAN 1 977.6274 1.1 41840 18494 2 977.631013 489.821 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3578.1 - 1.56E+06 - - - 3.7438 - 1.482 0.164 - 97.3 1 2 0 0.0037 10 0 0 0 9.38E+07 8.52E+07 - - - 1.3492 1 230117_WJC_METTL3_WT_vs_EV_F05.18495.18495.2 2.02E-05 20-Oct R.LYEAYLPETFR.R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1400.6976 2.24 41841 18495 2 1400.702529 701.3561 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3578.1 - 2.07E+06 - - - 3.5068 - 2.119 0.606 - 373 1 2 0 0.0049 11 0 0 0 5.73E+07 2.55E+07 - - - 5.5469 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18497.18497.2 0.00213 18-Nov R.LGLLGLPAPK[136.11].N sp|Q99459|CDC5L_HUMAN 1 985.6416 1.1 41843 18497 2 985.644082 493.8281 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3578.2 - 1.71E+06 - - - 2.5658 - 2.237 0.298 - 262.9 1 2 0 0.0025 10 0 0 0 9.38E+07 8.52E+07 - - - 3.4886 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.18498.18498.2 0.00374 14-Jul K.YLELLGYR.K "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 7 1025.5546 1.67 41844 18498 2 1025.557337 513.7846 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6 3578.2 - 1.16E+06 - - - 2.6864 - 1.605 0.388 - 175.4 1 2 0 0.0028 8 0 0 0 1.73E+07 1.04E+07 - - - 3.3328 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18499.18499.2 0.00032 20-Dec R.LYEAYLPETFR[166.11].R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1410.7059 2.26 41845 18499 2 1410.708386 706.3602 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3578.3 - 1.15E+06 - - - 1.7715 - 2.058 0.47 - 221.3 1 2 0 0.0025 11 0 0 0 5.76E+07 2.55E+07 - - - 4.4641 0.9945 230117_WJC_METTL3_WT_vs_EV_F05.18500.18500.2 0.0047 14-Jul K.MDELQLFR.G "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0T971|A0A7P0T971_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7P0Z4D1|A0A7P0Z4D1_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0T946|A0A7P0T946_HUMAN,tr|A0A7P0TBK7|A0A7P0TBK7_HUMAN" 14 1050.5168 0.91 41846 18500 2 1050.51727 526.2657 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.37 3578.3 - 927204 - - - 0.4322 - 1.603 0.078 - 258.5 1 2 0 0.0005 8 0 0 0 1.95E+07 2.15E+07 - - - 1.0401 0.9898 230117_WJC_METTL3_WT_vs_EV_F05.18501.18501.2 0.00691 14-Sep K.YLELLGYR[166.11].K "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 7 1035.5629 1.67 41847 18501 2 1035.565755 518.7887 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6 3578.4 - 873932 - - - 2.8033 - 1.789 0.001 - 271.6 1 2 0 0.0029 8 0 0 0 1.73E+07 1.04E+07 - - - 0.8017 0.9953 230117_WJC_METTL3_WT_vs_EV_F05.18502.18502.2 0.348 12-May R.LFLEFER[166.11].K "sp|O43663|PRC1_HUMAN,sp|Q96I25|SPF45_HUMAN,tr|H0YL53|H0YL53_HUMAN" 3 962.5101 2.5 41848 18502 2 962.51216 482.2623 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 3578.4 - 474442 - - - 2.1527 - 1.159 0.221 - 76.8 1 2 0 0.0021 7 0 0 0 2.83E+07 1.13E+07 - - - 1.1402 1 230117_WJC_METTL3_WT_vs_EV_F05.18509.18509.2 5.17E-06 15/30 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 15.03 41853 18509 2 1686.907846 844.4543 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3579.2 - 961586 - - - 8.1576 - 2.918 0.487 - 598.6 1 2 0 0.0138 16 0 0 0 4.39E+07 2.92E+06 - - - 5.2665 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.18511.18511.2 0.0196 14-Jun R.SFYLALYK.Q "sp|Q9BQ70|TCF25_HUMAN,tr|Q9H384|Q9H384_HUMAN,tr|H3BSS3|H3BSS3_HUMAN,tr|H3BQ53|H3BQ53_HUMAN" 4 1003.5379 0.88 41855 18511 2 1003.539126 502.7762 Transcription factor 25 OS=Homo sapiens OX=9606 GN=TCF25 PE=1 SV=1 8.22 3579.4 - 489687 - - - 1.2526 - 1.381 0.244 - 114.5 1 2 0 0.0013 8 0 0 0 4.53E+06 5.14E+06 - - - 1.8164 1 230117_WJC_METTL3_WT_vs_EV_F05.18512.18512.2 3.94E-05 20-Oct K.VIAEDEVLWYR.L "sp|Q8N3Y1|FBXW8_HUMAN,tr|A0A499FIY5|A0A499FIY5_HUMAN" 2 1391.7085 4.4 41856 18512 2 1391.711305 696.8615 F-box\WD repeat-containing protein 8 OS=Homo sapiens OX=9606 GN=FBXW8 PE=1 SV=2 4.14 3579.5 - 461951 - - - 2.004 - 2.246 0.458 - 279 1 2 0 0.0028 11 0 0 0 3.84E+06 8.72E+05 - - - 4.6119 1 230117_WJC_METTL3_WT_vs_EV_F05.18513.18513.2 0.000747 20-Dec K.LALDMEIATYR.K "sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|Q14CN4|K2C72_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 4 1294.6591 22.16 41857 18513 2 1294.661995 648.3368 "Keratin, type II cytoskeletal 74 OS=Homo sapiens OX=9606 GN=KRT74 PE=1 SV=2" 4.37 3579.6 - 414676 - - - 2.2183 - 2.678 0.456 - 728 1 2 0 0.0029 11 0 0 0 5.95E+06 2.68E+05 - - - 5.073 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.18514.18514.2 0.163 12-Aug K.IAFIAWK[136.11].S "sp|Q5UIP0|RIF1_HUMAN,tr|H7BZN3|H7BZN3_HUMAN" 2 855.5098 0.94 41858 18514 2 855.511306 428.7622 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 8.75 3579.7 - 402726 - - - 1.7487 - 1.502 0.212 - 182.3 1 2 0 0.0015 7 0 0 0 2.91E+06 3.08E+06 - - - 1.8953 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18517.18517.2 0.000684 20-Aug R.IFVFEPPPGVK[136.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 1236.6998 2.55 41861 18517 2 1236.702395 619.3572 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3580.1 - 266434 - - - 2.1016 - 1.679 0.45 - 159.1 1 2 0 0.0026 11 0 0 0 7.78E+06 3.06E+06 - - - 3.7657 0.9612 230117_WJC_METTL3_WT_vs_EV_F05.18521.18521.2 6.97 12-Jul K.DLLLPIK.T "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 3 810.5215 1.41 41863 18521 2 810.524254 406.268 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 5.84 3580.7 - 1.19E+06 - - - 3.4089 - 1.396 0.003 - 210.4 1 2 0 0.0028 7 0 0 0 1.72E+07 1.22E+07 - - - 0.1194 0.9743 230117_WJC_METTL3_WT_vs_EV_F05.18522.18522.2 10.4 12-Jul K.DLLLPIK[136.11].T "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 3 818.5357 1.49 41864 18522 2 818.538441 410.2751 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 5.84 3580.8 - 939196 - - - 3.3597 - 1.521 0.002 - 211.7 1 2 0 0.0027 7 0 0 0 1.72E+07 1.15E+07 - - - 0.3837 0.9853 230117_WJC_METTL3_WT_vs_EV_F05.18523.18523.2 2.72 14-Jul K.MDELQLFR[166.11].G "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0T971|A0A7P0T971_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7P0Z4D1|A0A7P0Z4D1_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0T946|A0A7P0T946_HUMAN,tr|A0A7P0TBK7|A0A7P0TBK7_HUMAN" 14 1060.5251 0.91 41865 18523 2 1060.530965 531.2698 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.37 3580.9 - 1.85E+06 - - - 5.5435 - 1.842 0.152 - 239.2 1 2 0 0.0059 8 0 0 0 1.95E+07 2.15E+07 - - - 2.0041 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.18524.18524.2 0.00554 18-Dec K.TNVALMC[160.03]MLR[166.11].E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1217.5958 1.02 41866 18524 2 1217.601186 609.8052 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 7.91 3581 - 597255 - - - 4.4029 - 2.183 0.424 - 621.9 1 2 0 0.0054 10 0 0 0 6.60E+06 6.46E+06 - - - 4.3502 0.9842 230117_WJC_METTL3_WT_vs_EV_F05.18526.18526.2 0.0209 14-Jun R.WVVPVLPK[136.11].G "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 944.5939 2 41868 18526 2 944.598261 473.3042 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3581.3 - 357185 - - - 4.6443 - 1.217 0.281 - 62.5 5 2 0 0.0044 8 0 0 0 8.64E+06 4.33E+06 - - - 1.3952 0.9859 230117_WJC_METTL3_WT_vs_EV_F05.18528.18528.2 0.024 12-Jul R.LQFLFAK.D "sp|Q7Z3K3|POGZ_HUMAN,tr|H0YCT3|H0YCT3_HUMAN" 2 865.5062 1.07 41870 18528 2 865.510377 433.7604 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 8.75 3581.5 - 270090 - - - 4.855 - 1.357 0.218 - 140.2 1 2 0 0.0042 7 0 0 0 4.93E+06 4.59E+06 - - - 1.6171 0.9899 230117_WJC_METTL3_WT_vs_EV_F05.18530.18530.2 0.112 12-Jun R.LQFLFAK[136.11].D "sp|Q7Z3K3|POGZ_HUMAN,tr|H0YCT3|H0YCT3_HUMAN" 2 873.5204 0.91 41872 18530 2 873.525208 437.7675 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 8.75 3581.8 - 223797 - - - 5.5328 - 1.489 0.28 - 95.6 1 2 0 0.0048 7 0 0 0 4.93E+06 5.44E+06 - - - 2.369 1 230117_WJC_METTL3_WT_vs_EV_F05.18536.18536.3 1.66E-08 20/60 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 24.4 41876 18536 3 1686.898886 563.3053 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3582.5 - 2.92E+06 - - - 2.8461 - 3.66 0.617 - 551.7 1 2 0 0.0048 16 0 0 0 4.46E+07 1.83E+06 - - - 8.7467 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.18540.18540.2 0.0547 14-Sep R.EALAFIIR[166.11].S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 941.5574 0.81 41880 18540 2 941.559353 471.786 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3582.9 - 631040 - - - 2.104 - 1.833 0.296 - 301.8 1 2 0 0.002 8 0 0 0 7.32E+06 9.00E+06 - - - 3.0542 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.18541.18541.2 0.00165 18-Oct K.TNVALMC[160.03]MLR.E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1207.5876 1.01 41881 18541 2 1207.59436 604.8011 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 7.91 3583 - 515006 - - - 5.6352 - 1.996 0.409 - 348.7 1 2 0 0.0068 10 0 0 0 6.55E+06 6.46E+06 - - - 3.9889 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.18542.18542.2 0.0378 16-Jul M.AILFAVVAR.G "sp|P51809|VAMP7_HUMAN,tr|E5RH06|E5RH06_HUMAN" 2 958.5964 1.24 41882 18542 2 958.598735 480.3055 Vesicle-associated membrane protein 7 OS=Homo sapiens OX=9606 GN=VAMP7 PE=1 SV=3 9.79 3583.1 - 483960 - - - 2.4494 - 1.81 0.293 - 125.1 1 2 0 0.0023 9 0 0 0 7.26E+06 5.85E+06 - - - 2.9209 1 230117_WJC_METTL3_WT_vs_EV_F05.18545.18545.2 2.31E-07 16/30 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 20.72 41885 18545 2 1696.90454 849.4585 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3583.5 - 202059 - - - 1.2876 - 3.245 0.56 - 738.5 1 2 0 0.0022 16 0 0 0 6.47E+07 3.12E+06 - - - 6.0705 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.18552.18552.2 0.0013 18-Oct R.YLNWIGVPTK[136.11].V "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|A0A1W2PNV9|A0A1W2PNV9_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN,tr|F6XNB3|F6XNB3_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 9 1197.6637 0.18 41891 18552 2 1197.668409 599.8391 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.59 3584.3 - 2.75E+06 - - - 3.8942 - 1.932 0.346 - 334.6 1 2 0 0.0047 10 0 0 0 5.20E+06 2.84E+07 - - - 3.4333 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.18555.18555.2 0.0391 16-Sep R.TTLLPGLLK.T sp|Q9NSD9|SYFB_HUMAN 1 954.6114 3.05 41894 18555 2 954.614487 478.313 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 8.41 3584.5 - 2.43E+06 - - - 3.2673 - 1.46 0.279 - 268.4 1 2 0 0.0031 9 0 0 0 1.93E+07 6.32E+06 - - - 2.1956 1 230117_WJC_METTL3_WT_vs_EV_F05.18556.18556.2 0.000403 18-Oct R.VLGLGLGC[160.03]LR.L "sp|Q9BRJ7|TIRR_HUMAN,tr|W4VSQ8|W4VSQ8_HUMAN,tr|K7EIN2|K7EIN2_HUMAN,tr|K7ENA3|K7ENA3_HUMAN" 4 1056.6114 3.97 41895 18556 2 1056.617753 529.313 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3584.6 - 1.51E+06 - - - 6.0268 - 2.297 0.506 - 308.5 1 2 0 0.0064 10 0 0 0 2.15E+07 5.42E+06 - - - 5.0976 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.18557.18557.2 0.00183 22-Nov K.GGIVGMTLPIAR.D "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 1183.6747 1.42 41896 18557 2 1183.678874 592.8446 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 9.75 3584.7 - 1.44E+06 - - - 3.5145 - 2.038 0.453 - 342.5 1 2 0 0.0042 12 0 0 0 1.81E+07 1.27E+07 - - - 4.2589 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18558.18558.2 0.0148 16-Aug R.LVLDWDSVR.A "sp|Q68EM7|RHG17_HUMAN,tr|C9IZD3|C9IZD3_HUMAN,tr|I3L4P6|I3L4P6_HUMAN" 3 1101.5819 2.48 41897 18558 2 1101.583213 551.7982 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4.21 3584.8 - 1.34E+06 - - - 1.2291 - 1.56 0.383 - 203.6 1 2 0 0.0014 9 0 0 0 2.64E+07 1.07E+07 - - - 3.1559 1 230117_WJC_METTL3_WT_vs_EV_F05.18559.18559.2 4.49E-05 16-Sep R.MADFWLTEK.D sp|Q9NRX2|RM17_HUMAN 1 1139.5321 1.35 41898 18559 2 1139.535949 570.7733 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 4.37 3584.9 - 1.31E+06 - - - 3.3496 - 2.036 0.502 - 281.2 1 2 0 0.0038 9 0 0 0 7.31E+06 5.40E+06 - - - 4.8045 0.9894 230117_WJC_METTL3_WT_vs_EV_F05.18560.18560.2 0.16 16-Jul R.GNLLLEQER[166.11].Q "sp|Q6ZSZ5|ARHGI_HUMAN,tr|A0A3B3IPE9|A0A3B3IPE9_HUMAN,tr|A0A590UK10|A0A590UK10_HUMAN,tr|M0QZS0|M0QZS0_HUMAN,tr|A0A087WZG4|A0A087WZG4_HUMAN,tr|A0A804CAZ4|A0A804CAZ4_HUMAN" 6 1080.5803 3.45 41899 18560 2 1080.583897 541.2974 Rho guanine nucleotide exchange factor 18 OS=Homo sapiens OX=9606 GN=ARHGEF18 PE=1 SV=4 4.53 3585 - 1.28E+06 - - - 3.3352 - 1.536 0.1 - 163.1 1 2 0 0.0036 9 0 0 0 2.05E+07 5.94E+06 - - - 1.0201 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.18563.18563.2 0.0246 16-Aug R.LFENYIELK.A sp|Q96KP1|EXOC2_HUMAN 1 1167.6176 0.92 41902 18563 2 1167.621325 584.8161 Exocyst complex component 2 OS=Homo sapiens OX=9606 GN=EXOC2 PE=1 SV=1 4.53 3585.4 - 816948 - - - 3.2108 - 1.547 0.332 - 164.9 1 2 0 0.0037 9 0 0 0 3.13E+06 3.41E+06 - - - 2.7543 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18564.18564.2 0.00206 22-Oct R.VPLSTVLLDPTR.S sp|Q9Y2I1|NISCH_HUMAN 1 1309.7606 1.67 41903 18564 2 1309.7641 655.8876 Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3 5.81 3585.5 - 414191 - - - 2.7089 - 2.054 0.394 - 190.7 1 2 0 0.0035 12 0 0 0 2.27E+06 1.36E+06 - - - 3.8439 1 230117_WJC_METTL3_WT_vs_EV_F05.18566.18566.2 8.24E-07 13/22 R.LLYMAIDGVAPR.A sp|Q9H0D6|XRN2_HUMAN 1 1317.7115 1.12 41905 18566 2 1317.717357 659.863 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3585.8 - 321446 - - - 4.4501 - 2.5 0.506 - 805.7 1 2 0 0.0059 12 0 0 0 5.65E+07 5.03E+07 - - - 5.1874 1 230117_WJC_METTL3_WT_vs_EV_F05.18567.18567.2 6.89E-06 20-Oct R.FYSLLDPSYAK.N sp|P46977|STT3A_HUMAN 1 1302.6496 1.32 41906 18567 2 1302.654205 652.3321 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 5.83 3585.9 - 294069 - - - 3.532 - 2.016 0.515 - 255.5 1 2 0 0.0046 11 0 0 0 1.55E+06 1.17E+06 - - - 4.74 0.9909 230117_WJC_METTL3_WT_vs_EV_F05.18568.18568.2 0.0453 20-Aug K.YAALYQPLFDK[136.11].R "sp|Q99733|NP1L4_HUMAN,tr|A8MXH2|A8MXH2_HUMAN,tr|C9J6D1|C9J6D1_HUMAN,tr|E9PJJ2|E9PJJ2_HUMAN,tr|E9PNW0|E9PNW0_HUMAN,tr|E9PKT8|E9PKT8_HUMAN,tr|E9PS34|E9PS34_HUMAN,tr|C9JZI7|C9JZI7_HUMAN,tr|E9PNJ7|E9PNJ7_HUMAN" 9 1335.6954 1.09 41907 18568 2 1335.700183 668.855 Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1 5.83 3586 - 229053 - - - 3.5517 - 1.416 0.172 - 170.2 1 2 0 0.0047 11 0 0 0 1.10E+06 1.01E+06 - - - 1.2509 1 230117_WJC_METTL3_WT_vs_EV_F05.18574.18574.2 2.49E-08 13/22 K.FGEAIGMGFPVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1251.6322 0.95 41912 18574 2 1251.638325 626.8234 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3586.8 - 2.80E+06 - - - 4.9096 - 2.551 0.604 - 591.2 1 2 0 0.0061 12 0 0 0 1.82E+08 1.92E+08 - - - 5.9643 1 230117_WJC_METTL3_WT_vs_EV_F05.18576.18576.2 3.16E-06 22-Oct R.LLYMAIDGVAPR[166.11].A sp|Q9H0D6|XRN2_HUMAN 1 1327.7198 1.12 41914 18576 2 1327.727882 664.8672 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3587.1 - 892157 - - - 6.115 - 2.22 0.504 - 369 1 2 0 0.0081 12 0 0 0 5.65E+07 5.03E+07 - - - 4.8594 0.9939 230117_WJC_METTL3_WT_vs_EV_F05.18577.18577.2 0.111 14-Jul R.WVVPVLPK.G "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 936.5797 2 41915 18577 2 936.583318 469.2971 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3587.2 - 751904 - - - 3.8908 - 1.414 0.228 - 162.7 1 2 0 0.0036 8 0 0 0 8.64E+06 4.33E+06 - - - 1.7687 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.18583.18583.2 0.000294 22-Oct R.VIQEGLEGLVLK.D sp|P49916|DNLI3_HUMAN 1 1296.7653 2.18 41921 18583 2 1296.771285 649.3899 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 4.53 3588 - 161461 - - - 4.613 - 1.849 0.401 - 238.4 1 2 0 0.006 12 0 0 0 2.07E+06 9.49E+05 - - - 3.6181 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.18587.18587.3 0.00189 14/56 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 1.55 41924 18587 3 1458.764194 487.2598 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3588.5 - 1.64E+06 - - - 4.6183 - 2.712 0.478 - 322.2 1 2 0 0.0067 15 0 0 0 3.81E+07 2.46E+07 - - - 6.4707 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18589.18589.2 0.0111 20-Sep K.LVFLGLDNAGK.T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1145.6445 1.56 41926 18589 2 1145.646567 573.8295 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3588.5 - 2.96E+06 - - - 1.84 - 1.964 0.396 - 235.8 1 2 0 0.0021 11 0 0 0 3.86E+08 2.47E+08 - - - 3.7912 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18590.18590.2 0.0888 20-Sep K.LVFLGLDNAGK[136.11].T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1153.6587 1.56 41927 18590 2 1153.660436 577.8366 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3588.6 - 2.43E+06 - - - 1.5403 - 1.947 0.443 - 230.5 1 2 0 0.0018 11 0 0 0 3.86E+08 2.47E+08 - - - 4.1149 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.18591.18591.2 0.0367 14-Jul R.EALAFIIR.S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 931.5491 1.46 41928 18591 2 931.550233 466.7818 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3588.6 - 1.47E+06 - - - 1.2141 - 1.675 0.211 - 210.8 1 2 0 0.0011 8 0 0 0 3.03E+07 2.07E+07 - - - 2.1548 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.18594.18594.2 3.3 12-Jun K.LIFYDLR[166.11].G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 948.5308 1.23 41931 18594 2 948.532667 475.2727 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3588.8 - 656176 - - - 1.9441 - 1.314 0.23 - 141.1 1 2 0 0.0018 7 0 0 0 4.07E+07 3.30E+07 - - - 1.6045 1 230117_WJC_METTL3_WT_vs_EV_F05.18598.18598.2 5.08E-05 14/22 R.IGFDVVTLSGTR[166.11].G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1273.6906 0.99 41935 18598 2 1273.69508 637.8526 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.84 3589.3 - 275144 - - - 3.5393 - 2.528 0.488 - 635.4 1 2 0 0.0045 12 0 0 0 7.28E+06 7.35E+06 - - - 5.0842 0.9903 230117_WJC_METTL3_WT_vs_EV_F05.18600.18600.2 4.84 12-Jun R.GLQDVLR.T "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 799.4552 14.78 41937 18600 2 799.456066 400.7349 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.84 3589.6 - 188871 - - - 1.0807 - 1.078 0.166 - 115.9 1 2 0 0.0009 7 0 0 0 4.66E+06 3.15E+05 - - - 0.5048 1 230117_WJC_METTL3_WT_vs_EV_F05.18601.18601.2 8.54E-06 13/22 R.GIYTGLSAGLLR.Q "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 1219.6925 0.7 41938 18601 2 1219.695977 610.8535 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 8.75 3589.7 - 163507 - - - 2.8737 - 2.2 0.576 - 395.3 1 2 0 0.0035 12 0 0 0 1.66E+07 2.38E+07 - - - 5.3688 1 230117_WJC_METTL3_WT_vs_EV_F05.18602.18602.2 2.68E-05 20-Nov R.VYPQAVYFPIR.T "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1351.7289 1.7 41939 18602 2 1351.732298 676.8717 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.56 3589.8 - 141990 - - - 2.5449 - 2.375 0.478 - 555.9 1 2 0 0.0034 11 0 0 0 2.26E+06 1.33E+06 - - - 4.9105 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.18606.18606.2 0.28 14-Jul R.ILFFNTPK.K "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 978.5539 1.31 41941 18606 2 978.55586 490.2842 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 8.75 3590.4 - 2.00E+06 - - - 2.05 - 1.473 0.25 - 115.5 1 2 0 0.002 8 0 0 0 5.82E+07 4.46E+07 - - - 2.055 0.9936 230117_WJC_METTL3_WT_vs_EV_F05.18607.18607.2 0.23 14-Jun R.ILFFNTPK[136.11].K "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 986.5681 1.25 41942 18607 2 986.569932 494.2913 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 8.75 3590.5 - 1.48E+06 - - - 1.9036 - 1.316 0.15 - 65.7 2 2 0 0.0019 8 0 0 0 5.82E+07 4.65E+07 - - - 0.842 0.9835 230117_WJC_METTL3_WT_vs_EV_F05.18608.18608.2 0.0154 16-Jul R.LVLDWDSVR[166.11].A "sp|Q68EM7|RHG17_HUMAN,tr|C9IZD3|C9IZD3_HUMAN,tr|I3L4P6|I3L4P6_HUMAN" 3 1111.5901 2.48 41943 18608 2 1111.596667 556.8023 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4.21 3590.6 - 1.62E+06 - - - 5.8817 - 1.428 0.276 - 117.3 1 2 0 0.0065 9 0 0 0 2.64E+07 1.07E+07 - - - 2.1082 0.9948 230117_WJC_METTL3_WT_vs_EV_F05.18610.18610.2 0.00809 14-Sep R.QAFYFALR.D "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1014.5287 1.99 41945 18610 2 1014.534273 508.2716 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.75 3590.9 - 1.04E+06 - - - 5.4922 - 1.687 0.342 - 254.8 1 2 0 0.0056 8 0 0 0 9.30E+06 4.67E+06 - - - 3.1425 0.9909 230117_WJC_METTL3_WT_vs_EV_F05.18611.18611.2 1.45 16-Aug R.ALLLSTYIK.F "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|A0A0G2JS82|A0A0G2JS82_HUMAN,tr|A0A0G2JQM1|A0A0G2JQM1_HUMAN" 4 1020.6219 1.33 41946 18611 2 1020.624983 511.3182 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 8.63 3591 - 965624 - - - 2.9884 - 1.644 0.096 - 154.5 3 2 0 0.0031 9 0 0 0 9.64E+06 7.23E+06 - - - 0.9742 0.9777 230117_WJC_METTL3_WT_vs_EV_F05.18612.18612.2 1.3 16-Jul R.ALLLSTYIK[136.11].F "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|A0A0G2JS82|A0A0G2JS82_HUMAN,tr|A0A0G2JQM1|A0A0G2JQM1_HUMAN" 4 1028.6361 1.33 41947 18612 2 1028.641228 515.3253 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 8.63 3591.1 - 695120 - - - 4.9532 - 1.578 0.144 - 116.4 2 2 0 0.0051 9 0 0 0 9.64E+06 7.23E+06 - - - 1.2882 0.9173 230117_WJC_METTL3_WT_vs_EV_F05.18613.18613.2 0.000519 14-Sep K.C[160.03]QLLFALK.V "sp|Q9BRJ7|TIRR_HUMAN,tr|K7EIN2|K7EIN2_HUMAN" 2 991.5525 1.03 41948 18613 2 991.543561 496.7835 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3591.3 - 622140 - - - -8.9889 - 1.763 0.37 - 267.4 1 2 0 -0.0089 8 0 0 0 1.12E+07 1.08E+07 - - - 3.4811 0.999 230117_WJC_METTL3_WT_vs_EV_F05.18617.18617.2 0.0159 18-Aug R.YYAFDEAFVR.E "sp|O43427|FIBP_HUMAN,tr|E9PSD3|E9PSD3_HUMAN,tr|E9PJW6|E9PJW6_HUMAN" 3 1279.5873 7.53 41952 18617 2 1279.588883 640.8009 Acidic fibroblast growth factor intracellular-binding protein OS=Homo sapiens OX=9606 GN=FIBP PE=1 SV=3 4.37 3591.8 - 352783 - - - 1.2066 - 1.408 0.325 - 135.1 1 2 0 0.0015 10 0 0 0 1.78E+06 2.37E+05 - - - 2.3961 0.9921 230117_WJC_METTL3_WT_vs_EV_F05.18624.18624.2 0.0401 12-Jul K.LIFYDLR.G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 938.5226 1.24 41958 18624 2 938.527831 470.2686 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3592.7 - 8.12E+06 - - - 5.6237 - 1.409 0.351 - 200.2 1 2 0 0.0053 7 0 0 0 4.08E+07 3.30E+07 - - - 2.7183 0.9919 230117_WJC_METTL3_WT_vs_EV_F05.18625.18625.2 0.0558 12-Jun R.VLVWDLR[166.11].N "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 909.5312 1.96 41959 18625 2 909.535508 455.7729 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.81 3592.7 - 5.62E+06 - - - 4.7827 - 1.416 0.263 - 209 1 2 0 0.0044 7 0 0 0 4.74E+07 2.41E+07 - - - 2.0843 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.18626.18626.2 0.000596 18-Jul K.ELLTSFGPLK.A "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1103.6227 1.58 41960 18626 2 1103.626388 552.8186 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6.1 3592.7 - 1.56E+07 - - - 3.3771 - 1.56 0.441 - 123.2 1 2 0 0.0037 10 0 0 0 5.99E+07 3.78E+07 - - - 3.5383 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18627.18627.2 0.000472 18-Jul K.ELLTSFGPLK[136.11].A "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1111.6369 1.59 41961 18627 2 1111.639837 556.8257 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6.1 3592.8 - 1.06E+07 - - - 2.6771 - 1.783 0.431 - 146.3 1 2 0 0.003 10 0 0 0 6.02E+07 3.78E+07 - - - 3.8376 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18628.18628.2 7.53E-05 20-Jul R.VLPSITTEILK.S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1212.7329 1.45 41962 18628 2 1212.735121 607.3737 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 3592.8 - 7.39E+06 - - - 1.7984 - 1.669 0.437 - 138.4 1 2 0 0.0022 11 0 0 0 3.34E+08 2.31E+08 - - - 3.6537 0.9644 230117_WJC_METTL3_WT_vs_EV_F05.18632.18632.2 7.33 12-Jun R.LTIAILR.H "sp|Q5XPI4|RN123_HUMAN,sp|Q96B70|LENG9_HUMAN,tr|C9J266|C9J266_HUMAN,tr|A0A087WVD1|A0A087WVD1_HUMAN,tr|C9JS59|C9JS59_HUMAN" 5 798.5327 2.53 41966 18632 2 798.534271 400.2736 E3 ubiquitin-protein ligase RNF123 OS=Homo sapiens OX=9606 GN=RNF123 PE=1 SV=1 9.75 3593 - 2.21E+06 - - - 1.9373 - 1.22 0.001 - 173.5 1 2 0 0.0015 7 0 0 0 6.00E+07 2.37E+07 - - - -0.322 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.18633.18633.2 0.0988 16-Sep R.VLAINILGR.F sp|O43747|AP1G1_HUMAN 1 967.6179 0.32 41967 18633 2 967.619491 484.8162 AP-1 complex subunit gamma-1 OS=Homo sapiens OX=9606 GN=AP1G1 PE=1 SV=5 9.72 3593.1 - 2.19E+06 - - - 1.6949 - 1.787 0.259 - 245.1 1 2 0 0.0016 9 0 0 0 6.22E+06 1.94E+07 - - - 2.633 0.972 230117_WJC_METTL3_WT_vs_EV_F05.18635.18635.2 4.25 12-Jun R.TLIGFLR.S "sp|O15116|LSM1_HUMAN,tr|E5RH18|E5RH18_HUMAN,tr|E5RJ47|E5RJ47_HUMAN" 3 818.5014 1.61 41969 18635 2 818.502467 410.258 U6 snRNA-associated Sm-like protein LSm1 OS=Homo sapiens OX=9606 GN=LSM1 PE=1 SV=1 9.41 3593.3 - 1.57E+06 - - - 1.2743 - 1.137 0.045 - 139.3 1 2 0 0.001 7 0 0 0 1.23E+07 7.66E+06 - - - -0.2201 1 230117_WJC_METTL3_WT_vs_EV_F05.18637.18637.2 1.19E-06 26-Nov K.IVIPNEESVVIYYK[136.11].L sp|P42285|MTREX_HUMAN 1 1672.9167 0.89 41971 18637 2 1672.919442 837.4656 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.53 3593.5 - 1.50E+06 - - - 1.6241 - 2.346 0.602 - 231.7 1 2 0 0.0027 14 0 0 0 3.47E+06 3.91E+06 - - - 5.6264 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.18638.18638.2 0.14 18-Aug R.LWTPPEDYRL.- "sp|Q9BYD1|RM13_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 2 1288.6452 1.69 41972 18638 2 1288.647452 645.3299 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.37 3593.5 - 1.28E+06 - - - 1.7569 - 1.763 0.219 - 244.7 1 2 0 0.0023 10 0 0 0 1.50E+07 8.85E+06 - - - 2.2405 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18642.18642.2 0.000247 26-Dec K.YILVTGGVISGIGK.G "sp|P17812|PYRG1_HUMAN,sp|Q9NRF8|PYRG2_HUMAN,tr|A0A3B3ITH9|A0A3B3ITH9_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 7 1375.8075 1.88 41976 18642 2 1375.811452 688.911 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 8.59 3594 - 406934 - - - 2.871 - 2.264 0.448 - 222.8 1 2 0 0.004 14 0 0 0 3.57E+06 1.89E+06 - - - 4.3992 1 230117_WJC_METTL3_WT_vs_EV_F05.18645.18645.2 4.28E-05 20-Nov R.VLPSITTEILK[136.11].S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1220.7471 1.45 41977 18645 2 1220.74844 611.3808 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 3594.4 - 7.94E+06 - - - 1.0649 - 1.934 0.52 - 404.7 1 2 0 0.0013 11 0 0 0 3.34E+08 2.31E+08 - - - 4.6657 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18647.18647.2 0.0535 16-Nov R.FEALNLSFK.N "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 12 1067.5651 1.69 41979 18647 2 1067.567405 534.7898 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 6 3594.6 - 7.37E+06 - - - 2.1151 - 2.137 0.367 - 312.3 1 2 0 0.0023 9 0 0 0 6.61E+07 3.92E+07 - - - 3.9479 0.948 230117_WJC_METTL3_WT_vs_EV_F05.18648.18648.2 0.0246 Aug-34 R.AADALVAGAISNGGLYVK.L sp|Q3MIX3|ADCK5_HUMAN 1 1688.9097 999 41980 18648 2 1688.905397 845.4621 Uncharacterized aarF domain-containing protein kinase 5 OS=Homo sapiens OX=9606 GN=ADCK5 PE=1 SV=3 5.88 3594.6 - 5.40E+06 - - - -2.5685 - 1.565 0.103 - 81.1 3 2 0 -0.0043 18 0 0 0 3.22E+07 0.00E+00 - - - 0.6884 1 230117_WJC_METTL3_WT_vs_EV_F05.18649.18649.2 2.65E-05 20-Nov K.FLEMC[160.03]NDLLAR.V "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1380.653 7.22 41981 18649 2 1380.656326 691.3338 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.37 3594.8 - 1.58E+06 - - - 2.4148 - 2.257 0.589 - 432.8 1 2 0 0.0033 11 0 0 0 2.13E+07 2.94E+06 - - - 5.5925 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.18650.18650.2 0.117 16-Aug K.ALLSALELK.K sp|P49454|CENPF_HUMAN 1 956.5906 1.05 41982 18650 2 956.591512 479.3026 Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3 6.05 3594.9 - 1.33E+06 - - - 0.9189 - 1.527 0.196 - 153.1 1 2 0 0.0009 9 0 0 0 5.42E+06 5.17E+06 - - - 1.713 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.18651.18651.2 0.438 18-Sep K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.23 41983 18651 2 1086.647936 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3595 - 1.18E+06 - - - 3.8697 - 1.784 0.197 - 191 1 2 0 0.0042 10 0 0 0 4.19E+08 3.41E+08 - - - 2.1105 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18652.18652.2 5.16E-06 26-Oct K.IVIPNEESVVIYYK.L sp|P42285|MTREX_HUMAN 1 1664.9025 -1 41984 18652 2 1664.90625 833.4585 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.53 3595.1 - 978400 - - - 2.2374 - 1.632 0.441 - 145.6 1 2 0 0.0037 14 0 0 0 0.00E+00 0.00E+00 - - - 3.5262 1 230117_WJC_METTL3_WT_vs_EV_F05.18653.18653.2 5.34E-05 20-Oct R.TIATALEYVYK.G "sp|P78537|BL1S1_HUMAN,tr|G8JLQ3|G8JLQ3_HUMAN" 2 1270.6809 1.5 41985 18653 2 1270.684093 636.3477 Biogenesis of lysosome-related organelles complex 1 subunit 1 OS=Homo sapiens OX=9606 GN=BLOC1S1 PE=1 SV=2 5.66 3595.3 - 965742 - - - 2.5089 - 2.108 0.507 - 218.8 1 2 0 0.0032 11 0 0 0 5.00E+06 3.34E+06 - - - 4.8021 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.18655.18655.2 4.43E-06 14/24 R.LIEETISIAMATK[136.11].E "sp|O95249|GOSR1_HUMAN,tr|E9PCW1|E9PCW1_HUMAN,tr|G5E9T8|G5E9T8_HUMAN" 3 1426.7833 0.74 41987 18655 2 1426.779569 714.3989 Golgi SNAP receptor complex member 1 OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 4.53 3595.5 - 268959 - - - -2.5925 - 2.36 0.391 - 477.7 1 2 0 -0.0037 13 0 0 0 2.19E+06 2.97E+06 - - - 4.1315 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18659.18659.2 0.00116 14-Oct R.FLIQNVLR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1001.6022 1.47 41989 18659 2 1001.603694 501.8084 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.75 3596 - 1.01E+07 - - - 1.4906 - 2.108 0.344 - 422.4 1 2 0 0.0015 8 0 0 0 1.04E+08 7.08E+07 - - - 3.8304 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.18661.18661.2 0.0081 14-Jul R.FLIQNVLR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1011.6105 1.47 41991 18661 2 1011.612371 506.8125 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.75 3596.2 - 8.32E+06 - - - 1.8782 - 1.681 0.283 - 214.9 1 2 0 0.0019 8 0 0 0 1.04E+08 7.06E+07 - - - 2.6971 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.18663.18663.2 0.27 18-Aug K.AIAINTFLPK[136.11].N sp|Q92615|LAR4B_HUMAN 1 1094.6579 1.15 41993 18663 2 1094.659885 548.3362 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3596.5 - 2.05E+06 - - - 1.785 - 1.679 0.158 - 146.4 2 2 0 0.002 10 0 0 0 1.37E+08 1.19E+08 - - - 1.5194 0.999 230117_WJC_METTL3_WT_vs_EV_F05.18664.18664.2 0.0341 18-Sep R.LWTPPEDYR[166.11]L.- "sp|Q9BYD1|RM13_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 2 1298.6535 1.69 41994 18664 2 1298.654261 650.334 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.37 3596.6 - 1.91E+06 - - - 0.6183 - 1.637 0.283 - 421.4 1 2 0 0.0008 10 0 0 0 1.50E+07 8.85E+06 - - - 2.5067 0.9864 230117_WJC_METTL3_WT_vs_EV_F05.18665.18665.2 1.04 12-Jul R.NLPFLIK[136.11].K sp|Q86TB9|PATL1_HUMAN 1 851.536 1.2 41995 18665 2 851.537814 426.7753 Protein PAT1 homolog 1 OS=Homo sapiens OX=9606 GN=PATL1 PE=1 SV=2 8.75 3596.7 - 1.73E+06 - - - 2.1009 - 1.214 0.095 - 165 1 2 0 0.0018 7 0 0 0 1.09E+07 9.04E+06 - - - 0.3566 1 230117_WJC_METTL3_WT_vs_EV_F05.18667.18667.2 0.00247 18-Oct K.LYGEFADPFK.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1185.5706 2.35 41997 18667 2 1185.572798 593.7926 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3596.9 - 1.34E+06 - - - 1.832 - 1.927 0.507 - 281.3 1 2 0 0.0022 10 0 0 0 1.06E+07 4.52E+06 - - - 4.616 1 230117_WJC_METTL3_WT_vs_EV_F05.18668.18668.2 9.78E-09 15/26 R.ALMGSPQLVAAVVR.T "sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9J826|C9J826_HUMAN" 5 1410.8017 999 41998 18668 2 1410.803997 706.4081 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 9.79 3597.1 - 1.11E+06 - - - 1.6246 - 2.815 0.519 - 678.6 1 2 0 0.0023 14 0 0 0 1.76E+07 0.00E+00 - - - 5.4708 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.18670.18670.2 0.0184 12-Jun R.EFIEMWR[166.11].L "sp|Q7L0Y3|TM10C_HUMAN,tr|C9JVB6|C9JVB6_HUMAN" 2 1019.4774 0.87 42000 18670 2 1019.478345 510.746 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 4.53 3597.3 - 840496 - - - 0.9191 - 1.36 0.288 - 99.9 1 2 0 0.0009 7 0 0 0 4.96E+06 5.73E+06 - - - 2.1422 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.18675.18675.2 0.0748 22-Sep K.LIDFGSAAYLER.G sp|Q96RG2|PASK_HUMAN 1 1353.6929 -1 42005 18675 2 1353.697257 677.8537 PAS domain-containing serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=PASK PE=1 SV=3 4.37 3598 - 395446 - - - 3.2437 - 1.873 0.385 - 196 1 2 0 0.0044 12 0 0 0 0.00E+00 0.00E+00 - - - 3.5344 0.9921 230117_WJC_METTL3_WT_vs_EV_F05.18677.18677.2 1.24 24-Aug K.ILTPLVSLDTPGK[136.11].A "sp|Q9HC38|GLOD4_HUMAN,tr|I3L1I0|I3L1I0_HUMAN,tr|F6TLX2|F6TLX2_HUMAN" 3 1360.8057 -1 42007 18677 2 1360.806641 681.4101 Glyoxalase domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GLOD4 PE=1 SV=1 5.84 3598.2 - 305590 - - - 0.6783 - 1.007 0.224 - 104.6 1 2 0 0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 0.7131 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18680.18680.2 1.51E-05 16-Oct R.SPTWFGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1059.5502 0.99 42009 18680 2 1059.553122 530.7824 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3598.6 - 1.48E+07 - - - 2.7908 - 2.022 0.456 - 476 1 2 0 0.003 9 0 0 0 3.40E+08 3.43E+08 - - - 4.445 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18685.18685.2 0.00675 18-Sep R.YDLGGLVMVK.D sp|Q15274|NADC_HUMAN 1 1093.5842 0.41 42014 18685 2 1093.585724 547.7994 Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Homo sapiens OX=9606 GN=QPRT PE=1 SV=3 5.83 3598.8 - 1.57E+06 - - - 1.4238 - 1.842 0.386 - 211.6 1 2 0 0.0016 10 0 0 0 3.19E+07 7.84E+07 - - - 3.5966 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18687.18687.2 0.000932 16-Jul K.LFTTMELMR.W sp|O00232|PSD12_HUMAN 1 1140.5671 2.02 42016 18687 2 1140.568239 571.2908 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 6 3598.9 - 1.34E+06 - - - 0.9662 - 1.655 0.493 - 180.6 1 2 0 0.0011 9 0 0 0 1.38E+07 6.86E+06 - - - 4.1395 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.18689.18689.2 0.0111 20-Sep K.YLLDSC[160.03]APLLR.Y sp|Q92616|GCN1_HUMAN 1 1319.6908 1 42018 18689 2 1319.688876 660.8527 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.83 3599.1 - 865891 - - - -1.4261 - 1.973 0.329 - 237.2 1 2 0 -0.0019 11 0 0 0 5.58E+06 5.60E+06 - - - 3.3088 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18690.18690.2 0.00101 20-Aug K.YLLDSC[160.03]APLLR[166.11].Y sp|Q92616|GCN1_HUMAN 1 1329.699 1 42019 18690 2 1329.698962 665.8568 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.83 3599.2 - 803749 - - - -0.0496 - 1.717 0.438 - 165.6 2 2 0 -0.0001 11 0 0 0 5.58E+06 5.60E+06 - - - 3.604 0.9717 230117_WJC_METTL3_WT_vs_EV_F05.18693.18693.2 0.0023 14-Jul K.FEFLGINR.Q sp|Q8N3X1|FNBP4_HUMAN 1 994.5236 1.48 42022 18693 2 994.520046 498.2691 Formin-binding protein 4 OS=Homo sapiens OX=9606 GN=FNBP4 PE=1 SV=3 6 3599.4 - 528211 - - - -3.5897 - 1.501 0.192 - 154.7 1 2 0 -0.0036 8 0 0 0 6.93E+06 4.68E+06 - - - 1.6829 1 230117_WJC_METTL3_WT_vs_EV_F05.18694.18694.2 0.221 20-Nov K.FLC[160.03]YLSQAGFR.V sp|Q7Z2T5|TRM1L_HUMAN 1 1360.6598 1.59 42023 18694 2 1360.665481 681.3372 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 8.22 3599.6 - 480343 - - - 4.1811 - 2.201 0.472 - 500 1 2 0 0.0057 11 0 0 0 7.51E+06 4.74E+06 - - - 4.6596 0.9957 230117_WJC_METTL3_WT_vs_EV_F05.18695.18695.2 0.0394 16-Jul K.FSPTDFLAK.M "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 1024.5229 1.33 42024 18695 2 1024.526044 513.2687 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.84 3599.6 - 370830 - - - 3.0229 - 1.253 0.256 - 108.4 1 2 0 0.0031 9 0 0 0 9.84E+06 7.42E+06 - - - 1.5833 0.9946 230117_WJC_METTL3_WT_vs_EV_F05.18696.18696.2 0.0964 12-Jul R.WFEAFVK.R "sp|Q99543|DNJC2_HUMAN,tr|F2Z3H0|F2Z3H0_HUMAN,tr|H7C3L7|H7C3L7_HUMAN,tr|F2Z3N9|F2Z3N9_HUMAN" 4 925.4698 0.68 42025 18696 2 925.471322 463.7422 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 6 3599.7 - 429993 - - - 1.6554 - 1.331 0.134 - 151.2 1 2 0 0.0015 7 0 0 0 6.98E+06 1.03E+07 - - - 0.9362 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.18701.18701.2 0.644 16-Oct R.ALVAVLLSR[166.11].T sp|Q92616|GCN1_HUMAN 1 950.6152 1.02 42028 18701 2 950.616039 476.3149 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.79 3600.4 - 1.21E+06 - - - 0.8594 - 1.798 0.151 - 498.6 1 2 0 0.0008 9 0 0 0 9.57E+06 9.41E+06 - - - 1.8533 1 230117_WJC_METTL3_WT_vs_EV_F05.18706.18706.2 4.06E-05 22-Dec K.IIATVLMTEDIK[136.11].L "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 1353.7669 0.23 42033 18706 2 1353.767046 677.8907 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 3601 - 465316 - - - 0.116 - 2.375 0.459 - 417 1 2 0 0.0002 12 0 0 0 1.07E+06 4.71E+06 - - - 4.7071 1 230117_WJC_METTL3_WT_vs_EV_F05.18707.18707.2 0.000262 20-Nov K.FLC[160.03]YLSQAGFR[166.11].V sp|Q7Z2T5|TRM1L_HUMAN 1 1370.6681 1.59 42034 18707 2 1370.669635 686.3413 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 8.22 3601.2 - 380021 - - - 1.1476 - 1.994 0.501 - 518.6 1 2 0 0.0016 11 0 0 0 7.29E+06 4.57E+06 - - - 4.6079 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18708.18708.2 0.00608 20-Aug R.ELAMQTFGVLK[136.11].E sp|Q9NVP1|DDX18_HUMAN 1 1243.6726 -1 42035 18708 2 1243.674588 622.8436 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 6.1 3601.3 - 360048 - - - 1.6025 - 1.736 0.364 - 142.7 1 2 0 0.002 11 0 0 0 0.00E+00 0.00E+00 - - - 3.221 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.18714.18714.2 0.000355 16-Aug R.YLTVAAVFR[166.11].G "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 5 1048.5945 2.88 42040 18714 2 1048.593277 525.3045 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3601.9 - 3.50E+06 - - - -1.153 - 1.734 0.504 - 194.4 1 2 0 -0.0012 9 0 0 0 7.40E+08 2.57E+08 - - - 4.3556 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.18715.18715.2 0.0676 14-Sep K.TVALWDLR.N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 972.5393 1.95 42041 18715 2 972.539223 487.2769 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3601.9 - 2.55E+06 - - - -0.0442 - 1.715 0.328 - 303.4 1 2 0 0 8 0 0 0 4.70E+08 2.41E+08 - - - 3.0904 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18720.18720.2 0.000109 20-Dec K.IGDFGLVTSLK.N "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 3 1148.6441 999 42046 18720 2 1148.644705 575.3293 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 5.84 3602.3 - 1.61E+06 - - - 0.5049 - 2.466 0.292 - 303.8 1 2 0 0.0006 11 0 0 0 2.29E+07 0.00E+00 - - - 3.6393 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.18721.18721.2 2.21 12-Jul R.YILDYLR.D "sp|Q96CX2|KCD12_HUMAN,sp|Q68DU8|KCD16_HUMAN" 2 954.5175 1.6 42047 18721 2 954.518116 478.266 BTB\POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1 5.83 3602.4 - 1.44E+06 - - - 0.6789 - 1.621 0.141 - 211.2 1 2 0 0.0006 7 0 0 0 1.45E+07 9.10E+06 - - - 1.6128 0.999 230117_WJC_METTL3_WT_vs_EV_F05.18724.18724.2 0.0869 20-Sep R.VEILPSYIPVR.V "sp|Q9UGJ1|GCP4_HUMAN,tr|H3BPU4|H3BPU4_HUMAN" 2 1284.7442 2.65 42050 18724 2 1284.746971 643.3794 Gamma-tubulin complex component 4 OS=Homo sapiens OX=9606 GN=TUBGCP4 PE=1 SV=1 5.97 3602.7 - 650629 - - - 2.1771 - 1.73 0.275 - 244.2 1 2 0 0.0028 11 0 0 0 5.23E+06 1.97E+06 - - - 2.5541 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18725.18725.2 0.121 18-Oct R.SIIFANYIAR.D "sp|Q7L523|RRAGA_HUMAN,sp|Q5VZM2|RRAGB_HUMAN,tr|Q5VZM0|Q5VZM0_HUMAN" 3 1166.6448 -1 42051 18725 2 1166.645441 584.3297 Ras-related GTP-binding protein A OS=Homo sapiens OX=9606 GN=RRAGA PE=1 SV=1 8.46 3602.8 - 385401 - - - 0.5546 - 1.945 0.332 - 328.6 1 2 0 0.0006 10 0 0 0 0.00E+00 0.00E+00 - - - 3.3499 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18729.18729.2 0.0314 16-Nov R.YLTVAAVFR.G "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 5 1038.5862 2.88 42053 18729 2 1038.586582 520.3004 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3603.2 - 3.07E+07 - - - 0.3524 - 2.106 0.438 - 399.2 1 2 0 0.0004 9 0 0 0 7.40E+08 2.57E+08 - - - 4.4307 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18731.18731.2 0.00699 18-Dec R.ILVATNLFGR.G "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 6 1102.6499 1.31 42055 18731 2 1102.649137 552.3322 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 9.75 3603.4 - 7.27E+06 - - - -0.6729 - 2.197 0.453 - 442.6 1 2 0 -0.0007 10 0 0 0 2.67E+08 2.03E+08 - - - 4.5836 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.18732.18732.2 0.0143 20-Nov K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 0.94 42056 18732 2 1197.720213 599.8679 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3603.4 - 5.85E+06 - - - -0.8742 - 2.363 0.41 - 404.1 1 2 0 -0.001 11 0 0 0 8.21E+08 8.78E+08 - - - 4.3953 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.18733.18733.2 0.012 14-Nov K.TVALWDLR[166.11].N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 982.5475 1.95 42057 18733 2 982.547402 492.281 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3603.5 - 4.58E+06 - - - -0.1364 - 1.852 0.35 - 340.9 1 2 0 -0.0001 8 0 0 0 4.70E+08 2.41E+08 - - - 3.4847 1 230117_WJC_METTL3_WT_vs_EV_F05.18734.18734.2 2.65E-06 13/20 K.VANVSLLALYK.G sp|P62266|RS23_HUMAN 1 1189.7071 0.94 42058 18734 2 1189.70541 595.8608 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3603.6 - 4.43E+06 - - - -1.3869 - 2.628 0.434 - 870.3 1 2 0 -0.0016 11 0 0 0 8.21E+08 8.78E+08 - - - 4.8599 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.18739.18739.2 0.0548 16-Sep R.ALVAVLLSR.T sp|Q92616|GCN1_HUMAN 1 940.607 1.02 42062 18739 2 940.606162 471.3108 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.79 3604.2 - 1.83E+06 - - - -0.8399 - 2.033 0.166 - 260.8 1 2 0 -0.0008 9 0 0 0 9.57E+06 9.41E+06 - - - 2.3195 1 230117_WJC_METTL3_WT_vs_EV_F05.18740.18740.2 7.94E-08 22-Nov K.FGEAIGMGFPVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1259.6464 0.97 42063 18740 2 1259.644752 630.8305 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3604.3 - 1.65E+06 - - - -1.2924 - 2.479 0.517 - 391.6 1 2 0 -0.0016 12 0 0 0 1.82E+08 1.88E+08 - - - 5.2478 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18742.18742.3 0.00469 14/40 R.ILVTLLHTLER.M sp|Q9BWD1|THIC_HUMAN 1 1306.7973 1.63 42065 18742 3 1306.795352 436.6064 "Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2" 6.75 3604.5 - 1.19E+06 - - - -1.4692 - 2.512 0.396 - 316.8 1 2 0 -0.0019 11 0 0 0 7.60E+06 4.67E+06 - - - 5.5711 0.9956 230117_WJC_METTL3_WT_vs_EV_F05.18745.18745.2 0.239 16-Sep R.NLILSAFPR.N sp|A5YKK6|CNOT1_HUMAN 1 1029.5971 11.17 42068 18745 2 1029.59706 515.8058 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 9.75 3604.9 - 1.01E+06 - - - -0.0534 - 1.521 0.155 - 256.8 1 2 0 -0.0001 9 0 0 0 1.07E+07 9.55E+05 - - - 1.3991 0.9811 230117_WJC_METTL3_WT_vs_EV_F05.18757.18757.2 0.377 12-Jul K.WMGIAFR[166.11].L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 889.4508 1.48 42079 18757 2 889.450851 445.7327 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.75 3606.2 - 1.32E+06 - - - 0.0585 - 0.977 0.177 - 148.8 1 2 0 0.0001 7 0 0 0 1.88E+07 1.27E+07 - - - 0.2746 0.9068 230117_WJC_METTL3_WT_vs_EV_F05.18758.18758.2 0.049 12-Aug L.SGFLVWR.R "sp|Q9NP84|TNR12_HUMAN,sp|Q96T88|UHRF1_HUMAN,tr|I3L1J9|I3L1J9_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 6 863.4654 1.42 42080 18758 2 863.464482 432.74 Tumor necrosis factor receptor superfamily member 12A OS=Homo sapiens OX=9606 GN=TNFRSF12A PE=1 SV=1 9.47 3606.4 - 1.12E+06 - - - -1.0319 - 1.752 0.339 - 247.5 1 1 0 -0.0009 7 0 0 0 1.05E+07 7.37E+06 - - - 3.3214 0.9946 230117_WJC_METTL3_WT_vs_EV_F05.18759.18759.2 0.0688 12-Aug K.WMGIAFR.L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 879.4425 1.48 42081 18759 2 879.441638 440.7285 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.75 3606.4 - 1.06E+06 - - - -1.0131 - 1.436 0.208 - 263.5 1 2 0 -0.0009 7 0 0 0 1.95E+07 1.31E+07 - - - 1.7236 0.9468 230117_WJC_METTL3_WT_vs_EV_F05.18760.18760.2 0.132 12-May R.GLFDSFR.R "sp|Q96IK1|BOD1_HUMAN,sp|Q8IYS8|BD1L2_HUMAN,tr|C9JNZ5|C9JNZ5_HUMAN" 3 840.413 2.07 42082 18760 2 840.411425 421.2138 Biorientation of chromosomes in cell division protein 1 OS=Homo sapiens OX=9606 GN=BOD1 PE=1 SV=2 5.84 3606.6 - 620273 - - - -1.8776 - 1.099 0.139 - 106.3 1 2 0 -0.0016 7 0 0 0 5.43E+06 2.63E+06 - - - 0.3663 1 230117_WJC_METTL3_WT_vs_EV_F05.18761.18761.2 4.22E-05 22-Dec K.SLAMEMVLTGDR.L sp|P30084|ECHM_HUMAN 1 1321.637 1.55 42083 18761 2 1321.642951 661.8258 "Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4" 4.37 3606.7 - 362136 - - - 4.4967 - 2.564 0.486 - 244.2 1 2 0 0.0059 12 0 0 0 5.47E+06 3.52E+06 - - - 5.1062 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.18766.18766.2 0.0288 18-Nov R.FLLQDTVELR.E "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1232.6765 1.77 42086 18766 2 1232.674642 617.3455 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3607.3 - 3.19E+06 - - - -1.4976 - 2.317 0.354 - 527.7 1 2 0 -0.0018 10 0 0 0 1.08E+08 6.10E+07 - - - 4.0005 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.18767.18767.2 0.000631 18-Aug R.FEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1252.6088 12.01 42087 18767 2 1252.606703 627.3117 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3607.3 - 3.91E+06 - - - -1.6757 - 1.935 0.454 - 199.5 1 2 0 -0.0021 10 0 0 0 7.88E+08 6.56E+07 - - - 4.2361 0.8775 230117_WJC_METTL3_WT_vs_EV_F05.18772.18772.2 0.019 12-Aug L.SGFLVWR[166.11].R "sp|Q9NP84|TNR12_HUMAN,sp|Q96T88|UHRF1_HUMAN,tr|I3L1J9|I3L1J9_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 6 873.4736 1.44 42092 18772 2 873.473037 437.7441 Tumor necrosis factor receptor superfamily member 12A OS=Homo sapiens OX=9606 GN=TNFRSF12A PE=1 SV=1 9.47 3607.8 - 722895 - - - -0.6938 - 1.7 0.261 - 208.7 1 1 0 -0.0006 7 0 0 0 1.06E+07 7.37E+06 - - - 2.6499 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.18773.18773.2 0.0195 16-Sep R.LDALLAELR[166.11].A sp|Q96L58|B3GT6_HUMAN 1 1022.6 1.48 42093 18773 2 1022.599847 512.3073 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 4.37 3607.9 - 521645 - - - -0.1164 - 2.326 0.212 - 327.3 1 2 0 -0.0001 9 0 0 0 2.03E+07 1.37E+07 - - - 3.049 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.18774.18774.2 0.0179 18-Oct R.FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1262.6171 12.01 42094 18774 2 1262.615264 632.3158 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3608.1 - 514202 - - - -1.4319 - 2.089 0.38 - 346.2 1 2 0 -0.0018 10 0 0 0 7.88E+08 6.56E+07 - - - 3.9034 0.9912 230117_WJC_METTL3_WT_vs_EV_F05.18777.18777.2 0.105 12-Sep R.FVLNLIK.L sp|Q8TDN6|BRX1_HUMAN 1 845.5375 0.77 42097 18777 2 845.536346 423.776 Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2 8.75 3608.4 - 335529 - - - -1.3352 - 1.465 0.167 - 222.4 1 2 0 -0.0011 7 0 0 0 2.90E+07 3.77E+07 - - - 1.484 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.18779.18779.2 0.684 18-Sep K.LLALGLVAER.R sp|Q9UNS1|TIM_HUMAN 1 1053.6546 1.48 42098 18779 2 1053.653092 527.8346 Protein timeless homolog OS=Homo sapiens OX=9606 GN=TIMELESS PE=1 SV=2 6 3608.7 - 140873 - - - -1.4597 - 1.713 0.221 - 195.9 1 2 0 -0.0015 10 0 0 0 3.13E+06 2.11E+06 - - - 2.1752 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18784.18784.2 0.000294 13/18 K.IEVIEIMTDR[166.11].G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1227.6408 0.94 42101 18784 2 1227.641037 614.8277 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3609.3 - 1.34E+06 - - - 0.1572 - 2.519 0.399 - 720.4 1 2 0 0.0002 10 0 0 0 1.92E+08 2.05E+08 - - - 4.5667 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.18786.18786.2 0.00336 16-Oct R.LDALLAELR.A sp|Q96L58|B3GT6_HUMAN 1 1012.5917 0.83 42103 18786 2 1012.591091 507.3031 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 4.37 3609.5 - 974677 - - - -0.5975 - 2.511 0.196 - 436.1 1 2 0 -0.0006 9 0 0 0 1.08E+07 1.31E+07 - - - 3.152 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.18787.18787.2 0.426 14-Aug R.ILLTLGIR.L "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 897.6011 1.2 42104 18787 2 897.59979 449.8078 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 9.75 3609.7 - 838702 - - - -1.5018 - 1.763 0.281 - 198.6 1 2 0 -0.0013 8 0 0 0 4.48E+06 3.75E+06 - - - 2.8261 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18790.18790.2 0.00861 14-Jul K.VFGFDSFK.T "sp|O94762|RECQ5_HUMAN,tr|J3KTQ2|J3KTQ2_HUMAN" 2 945.4596 0.44 42107 18790 2 945.46031 473.7371 ATP-dependent DNA helicase Q5 OS=Homo sapiens OX=9606 GN=RECQL5 PE=1 SV=2 5.81 3610 - 500231 - - - 0.7309 - 1.318 0.443 - 133.8 1 2 0 0.0007 8 0 0 0 3.73E+06 8.52E+06 - - - 3.1455 1 230117_WJC_METTL3_WT_vs_EV_F05.18791.18791.2 3.23E-05 24-Dec K.AEPLLGAPGELLK.Q sp|P17482|HXB9_HUMAN 1 1306.7497 2.45 42108 18791 2 1306.745599 654.3821 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 3610.2 - 422721 - - - -3.1024 - 2.247 0.535 - 372.5 1 2 0 -0.0041 13 0 0 0 1.71E+07 6.99E+06 - - - 5.0691 1 230117_WJC_METTL3_WT_vs_EV_F05.18792.18792.2 2.17E-05 24-Dec K.DIPVLVATDVAAR.G "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1338.7507 1.45 42109 18792 2 1338.75031 670.3826 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3610.3 - 328324 - - - -0.3033 - 2.291 0.485 - 475.2 1 2 0 -0.0004 13 0 0 0 4.54E+06 3.13E+06 - - - 4.7507 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.18796.18796.2 0.0308 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 6.35 42112 18796 2 1006.573978 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3610.8 - 179074 - - - 4.0534 - 1.911 0.443 - 256.4 1 2 0 0.0041 9 0 0 0 4.32E+07 6.80E+06 - - - 4.1853 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18798.18798.2 0.85 16-Sep R.VEFILEQMR.L sp|O00232|PSD12_HUMAN 1 1163.6009 1.5 42113 18798 2 1163.60095 582.8077 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.53 3611 - 356496 - - - 0.0602 - 2.034 0.392 - 452.2 1 2 0 0.0001 9 0 0 0 1.01E+07 6.70E+06 - - - 3.9904 0.9518 230117_WJC_METTL3_WT_vs_EV_F05.18799.18799.2 14.6 12-Jun R.VLFLIPK.N "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q5JV98|Q5JV98_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|H0Y630|H0Y630_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 13 828.5473 2.29 42114 18799 2 828.547496 415.2809 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 8.72 3611.1 - 822165 - - - 0.2221 - 1.097 0.036 - 164.8 1 2 0 0.0002 7 0 0 0 3.45E+07 1.51E+07 - - - -0.3998 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.18801.18801.2 0.336 12-May R.VLFLIPK[136.11].N "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q5JV98|Q5JV98_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|H0Y630|H0Y630_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 13 836.5615 2.28 42116 18801 2 836.561824 419.288 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 8.72 3611.2 - 623725 - - - 0.373 - 1.228 0.277 - 56 4 2 0 0.0003 7 0 0 0 3.44E+07 1.51E+07 - - - 1.4687 0.9949 230117_WJC_METTL3_WT_vs_EV_F05.18805.18805.2 0.0188 24-Oct K.AEPLLGAPGELLK[136.11].Q sp|P17482|HXB9_HUMAN 1 1314.7639 2.88 42120 18805 2 1314.76184 658.3892 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 3611.6 - 152455 - - - -1.5311 - 1.569 0.255 - 156.9 1 2 0 -0.002 13 0 0 0 1.63E+07 5.65E+06 - - - 2.0799 1 230117_WJC_METTL3_WT_vs_EV_F05.18810.18810.2 5.99E-06 20-Oct K.NAVEEYVYEFR.D "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1417.6514 -1 42125 18810 2 1417.650609 709.833 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.25 3612.2 - 0 - - - -0.5544 - 2.303 0.508 - 500.5 1 2 0 -0.0008 11 0 0 0 0.00E+00 0.00E+00 - - - 5.0496 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18825.18825.2 8.12E-05 13/20 R.IGFVGFPSVGK.S sp|Q9Y295|DRG1_HUMAN 1 1106.6124 1.73 42136 18825 2 1106.614396 554.3135 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 8.75 3613.8 - 4.15E+06 - - - 1.7757 - 2.09 0.437 - 443.7 1 2 0 0.002 11 0 0 0 9.04E+07 5.23E+07 - - - 4.2623 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18827.18827.2 1.56E-05 20-Dec K.TPPPVLIFAEK.K sp|Q9UJV9|DDX41_HUMAN 1 1210.6962 1.58 42138 18827 2 1210.695785 606.3554 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3613.9 - 2.40E+06 - - - -0.3106 - 2.024 0.478 - 421.8 1 2 0 -0.0004 11 0 0 0 1.20E+08 7.64E+07 - - - 4.4788 1 230117_WJC_METTL3_WT_vs_EV_F05.18830.18830.2 0.00223 20-Dec K.FAVALLDDSVR.V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1204.6452 1.83 42141 18830 2 1204.636375 603.3299 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 4.21 3614.3 - 1.14E+06 - - - -7.3158 - 2.556 0.494 - 522.9 1 2 0 -0.0088 11 0 0 0 3.63E+07 1.99E+07 - - - 5.2256 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18833.18833.2 0.000469 20-Aug R.YLLEQDFPGMR.L "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN" 2 1367.6544 2.49 42144 18833 2 1367.655979 684.8345 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.37 3614.7 - 608633 - - - 1.175 - 1.685 0.349 - 241.3 1 2 0 0.0016 11 0 0 0 4.39E+06 1.77E+06 - - - 3.0297 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18839.18839.2 0.000951 20-Oct R.LAVDLSEVVIK.W "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1184.7016 0.3 42149 18839 2 1184.703008 593.3581 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.37 3615.4 - 1.06E+06 - - - 1.1547 - 1.882 0.436 - 285 1 2 0 0.0014 11 0 0 0 1.63E+07 5.37E+07 - - - 3.9715 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18842.18842.2 0.042 20-Nov R.IGFVGFPSVGK[136.11].S sp|Q9Y295|DRG1_HUMAN 1 1114.6266 1.72 42152 18842 2 1114.626872 558.3206 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 8.75 3615.6 - 2.52E+06 - - - 0.2162 - 1.92 0.371 - 324.3 1 2 0 0.0002 11 0 0 0 9.02E+07 5.23E+07 - - - 3.5458 0.9944 230117_WJC_METTL3_WT_vs_EV_F05.18843.18843.2 0.115 14-Jul R.DLTDYLMK[136.11].L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 1005.4932 1.1 42153 18843 2 1005.493335 503.7539 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3615.6 - 498542 - - - 0.1004 - 1.188 0.215 - 154.9 1 2 0 0.0001 8 0 0 0 8.44E+07 7.67E+07 - - - 1.1485 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.18846.18846.2 0.0216 14/22 K.IIENELEGFGIR.L sp|Q9Y295|DRG1_HUMAN 1 1388.73 1.55 42154 18846 2 1388.729071 695.3723 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3616 - 719976 - - - -0.6546 - 2.102 0.402 - 628.7 1 2 0 -0.0009 12 0 0 0 2.34E+07 1.51E+07 - - - 3.9646 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18847.18847.2 0.00309 16-Sep R.NPNLLFTLK[136.11].V sp|Q96S59|RANB9_HUMAN 1 1066.6266 1.2 42155 18847 2 1066.628451 534.3206 Ran-binding protein 9 OS=Homo sapiens OX=9606 GN=RANBP9 PE=1 SV=1 8.75 3616.2 - 504032 - - - 1.7063 - 1.526 0.408 - 198.7 1 2 0 0.0018 9 0 0 0 1.89E+07 1.57E+07 - - - 3.2767 0.9956 230117_WJC_METTL3_WT_vs_EV_F05.18848.18848.2 0.0118 16-Sep K.GFGFVSFER[166.11].H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1054.5112 0.97 42156 18848 2 1054.516703 528.2629 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3616.3 - 790535 - - - 5.265 - 1.69 0.352 - 255.8 1 2 0 0.0056 9 0 0 0 4.60E+08 4.74E+08 - - - 3.1572 0.999 230117_WJC_METTL3_WT_vs_EV_F05.18849.18849.2 0.0163 14-Aug R.DLTDYLMK.L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 997.479 1.1 42157 18849 2 997.481847 499.7468 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3616.4 - 668210 - - - 2.8201 - 1.468 0.366 - 186.5 1 2 0 0.0028 8 0 0 0 8.44E+07 7.67E+07 - - - 2.9012 1 230117_WJC_METTL3_WT_vs_EV_F05.18850.18850.2 0.000138 13/22 K.IIENELEGFGIR[166.11].L sp|Q9Y295|DRG1_HUMAN 1 1398.7383 1.55 42158 18850 2 1398.740033 700.3764 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3616.5 - 483322 - - - 1.2747 - 2.665 0.536 - 506.4 1 2 0 0.0018 12 0 0 0 2.34E+07 1.51E+07 - - - 5.5784 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.18854.18854.2 0.54 14-Aug R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 1.33 42162 18854 2 898.524759 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 3617.1 - 189603 - - - 1.2721 - 1.722 0.175 - 153.6 1 2 0 0.0011 8 0 0 0 1.43E+07 1.08E+07 - - - 1.9723 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18855.18855.2 0.0129 24-Nov R.LDYLGVSYGLTPR[166.11].L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1462.7695 0.8 42163 18855 2 1462.773409 732.3921 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.83 3617.2 - 65189.9 - - - 2.6381 - 1.98 0.395 - 361.9 1 2 0 0.0039 13 0 0 0 8.29E+06 1.03E+07 - - - 3.7104 1 230117_WJC_METTL3_WT_vs_EV_F05.18861.18861.2 1.15E-06 22-Dec K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 1.67 42167 18861 2 1263.693266 632.853 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3617.8 - 447289 - - - 1.464 - 2.162 0.553 - 359.4 1 2 0 0.0019 12 0 0 0 3.65E+07 2.19E+07 - - - 5.1536 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18862.18862.2 0.000226 16-Sep K.GFGFVSFER.H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1044.5029 0.97 42168 18862 2 1044.503381 523.2587 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3617.9 - 1.85E+06 - - - 0.4787 - 1.851 0.41 - 321.7 1 2 0 0.0005 9 0 0 0 4.61E+08 4.75E+08 - - - 3.8504 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.18863.18863.2 0.0429 12-Jun K.DYVDLFR.H sp|P78527|PRKDC_HUMAN 1 926.4498 0.49 42169 18863 2 926.450937 464.2322 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.21 3618 - 617927 - - - 1.2467 - 1.303 0.226 - 165.8 1 2 0 0.0012 7 0 0 0 2.04E+07 4.15E+07 - - - 1.5485 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18872.18872.2 0.000111 16-Sep K.GLDFALLQK[136.11].V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1011.5844 1.26 42176 18872 2 1011.587094 506.7995 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3618.9 - 2.99E+06 - - - 2.6315 - 1.827 0.486 - 243.4 1 2 0 0.0027 9 0 0 0 6.74E+07 5.35E+07 - - - 4.3733 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.18881.18881.2 0.0121 20-Sep R.LAQPYVGVFLK.R "sp|P36776|LONM_HUMAN,tr|K7EQF8|K7EQF8_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN" 4 1233.7121 0.99 42185 18881 2 1233.715892 617.8633 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 8.59 3619.9 - 497702 - - - 3.0372 - 1.769 0.285 - 187.8 1 2 0 0.0037 11 0 0 0 5.37E+06 5.42E+06 - - - 2.6879 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.18886.18886.2 0.00481 20-Oct K.TPPPVLIFAEK[136.11].K sp|Q9UJV9|DDX41_HUMAN 1 1218.7104 1.58 42188 18886 2 1218.712238 610.3625 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3620.5 - 2.69E+06 - - - 1.5402 - 1.263 0.404 - 224 1 2 0 0.0019 11 0 0 0 1.21E+08 7.64E+07 - - - 2.656 0.9615 230117_WJC_METTL3_WT_vs_EV_F05.18887.18887.2 0.0301 18-Nov R.TLDLPIYVTR.V "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 5 1189.6707 0.88 42189 18887 2 1189.66293 595.8426 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.5 3620.6 - 757688 - - - -6.5094 - 1.856 0.345 - 378.2 1 2 0 -0.0077 10 0 0 0 1.77E+07 2.01E+07 - - - 3.3129 1 230117_WJC_METTL3_WT_vs_EV_F05.18888.18888.2 4.18E-07 13/22 K.NIEDVIAQGIGK.L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1255.6772 1.67 42190 18888 2 1255.680854 628.8459 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3620.7 - 1.48E+06 - - - 2.8972 - 2.259 0.515 - 347.1 1 2 0 0.0036 12 0 0 0 3.65E+07 2.19E+07 - - - 4.9878 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.18890.18890.2 0.0332 14-Sep R.ITNWLVLK.N "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN,tr|H3BRT3|H3BRT3_HUMAN" 3 985.5961 1.93 42192 18890 2 985.599016 493.8053 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 8.75 3621 - 481811 - - - 3.0063 - 1.99 0.356 - 169.6 1 2 0 0.003 8 0 0 0 9.26E+06 4.81E+06 - - - 3.7449 0.8818 230117_WJC_METTL3_WT_vs_EV_F05.18893.18893.2 8.42 20-Jul K.VLFGEDDSLLR[166.11].V "sp|Q92560|BAP1_HUMAN,tr|F8W6N3|F8W6N3_HUMAN,tr|H0Y8E8|H0Y8E8_HUMAN" 3 1272.6589 1.06 42195 18893 2 1272.657052 637.3367 Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Homo sapiens OX=9606 GN=BAP1 PE=1 SV=2 4.03 3621.4 - 171964 - - - -1.4812 - 1.044 0.083 - 46.8 2 2 0 -0.0019 11 0 0 0 2.96E+06 2.78E+06 - - - -0.3645 0.9926 230117_WJC_METTL3_WT_vs_EV_F05.18894.18894.2 0.00445 26-Nov K.LNLVDLAGSENIGR.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1469.7838 0.03 42196 18894 2 1469.792954 735.8992 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 3621.5 - 138836 - - - 6.2234 - 1.997 0.346 - 384 1 2 0 0.0091 14 0 0 0 2.50E+06 9.07E+07 - - - 3.3293 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.18900.18900.2 0.00219 14-Aug K.IDILTELR[166.11].D "sp|O00139|KIF2A_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 981.5734 1.32 42200 18900 2 981.574452 491.794 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.37 3622.3 - 1.20E+07 - - - 1.0544 - 1.776 0.279 - 213.9 1 2 0 0.001 8 0 0 0 8.76E+07 6.62E+07 - - - 2.8336 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.18901.18901.2 3.98 16-Sep K.LTQILSYLR[166.11].Q sp|Q13123|RED_HUMAN 1 1115.6578 1.44 42201 18901 2 1115.663064 558.8362 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3622.3 - 7.97E+06 - - - 4.7048 - 1.895 0.28 - 324.9 1 2 0 0.0053 9 0 0 0 9.51E+07 6.62E+07 - - - 2.9567 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18902.18902.2 0.000948 16-Sep K.GLDFALLQK.V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1003.5702 1.22 42202 18902 2 1003.571794 502.7924 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3622.4 - 1.59E+07 - - - 1.5564 - 1.887 0.415 - 253.7 1 2 0 0.0016 9 0 0 0 6.32E+07 5.20E+07 - - - 3.9428 0.999 230117_WJC_METTL3_WT_vs_EV_F05.18903.18903.2 0.0474 18-Jul K.LEPAFLSGLR.C "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1101.6182 1.49 42203 18903 2 1101.620781 551.8164 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3622.4 - 3.07E+06 - - - 2.3021 - 1.66 0.299 - 133.2 1 2 0 0.0025 10 0 0 0 1.48E+07 9.97E+06 - - - 2.6633 1 230117_WJC_METTL3_WT_vs_EV_F05.18904.18904.2 0.000165 18-Oct K.C[160.03]LEEFELLGK.A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1236.606 0.97 42204 18904 2 1236.608335 619.3103 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3622.5 - 2.01E+06 - - - 1.868 - 2.002 0.528 - 279.6 1 2 0 0.0023 10 0 0 0 1.11E+07 1.14E+07 - - - 4.8777 1 230117_WJC_METTL3_WT_vs_EV_F05.18905.18905.2 1.39E-05 14/24 R.ILLAEVPTMAVEK[136.11].V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1420.8091 5.92 42205 18905 2 1420.810895 711.4118 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3622.6 - 1.33E+06 - - - 1.2711 - 2.546 0.511 - 579.8 1 2 0 0.0018 13 0 0 0 5.28E+07 8.91E+06 - - - 5.2132 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.18907.18907.2 0.044 16-Aug R.FDLIGLEGR.V "sp|Q6ZRS2|SRCAP_HUMAN,tr|A0A0C4DFX4|A0A0C4DFX4_HUMAN,tr|A0A0A0MS59|A0A0A0MS59_HUMAN,tr|A0A087X0E3|A0A087X0E3_HUMAN" 4 1018.5447 1.08 42207 18907 2 1018.546204 510.2796 Helicase SRCAP OS=Homo sapiens OX=9606 GN=SRCAP PE=1 SV=3 4.37 3622.8 - 1.13E+06 - - - 1.4324 - 1.453 0.233 - 181 1 2 0 0.0015 9 0 0 0 9.60E+06 8.91E+06 - - - 1.8424 0.997 230117_WJC_METTL3_WT_vs_EV_F05.18908.18908.2 0.149 18-Jun K.LLLGDLAPVR[166.11].G sp|Q9NUQ8|ABCF3_HUMAN 1 1075.6629 4.83 42208 18908 2 1075.665586 538.8387 ATP-binding cassette sub-family F member 3 OS=Homo sapiens OX=9606 GN=ABCF3 PE=1 SV=2 5.84 3622.9 - 1.07E+06 - - - 2.4971 - 1.26 0.264 - 71.6 1 2 0 0.0027 10 0 0 0 2.03E+07 4.21E+06 - - - 1.6352 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.18910.18910.2 0.0145 20-Sep R.LEPLVNDLTLR.L sp|Q70UQ0|IKIP_HUMAN 1 1281.7293 1.99 42210 18910 2 1281.732794 641.8719 Inhibitor of nuclear factor kappa-B kinase-interacting protein OS=Homo sapiens OX=9606 GN=IKBIP PE=1 SV=1 4.37 3623.1 - 1.06E+06 - - - 2.7635 - 1.823 0.258 - 204.7 1 2 0 0.0035 11 0 0 0 1.71E+07 8.59E+06 - - - 2.5699 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18914.18914.2 0.00338 16-Oct K.LTQILSYLR.Q sp|Q13123|RED_HUMAN 1 1105.6495 1.44 42213 18914 2 1105.651718 553.832 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3623.6 - 3.20E+06 - - - 1.9654 - 2.212 0.42 - 435.2 1 2 0 0.0022 9 0 0 0 9.52E+07 6.62E+07 - - - 4.4392 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.18916.18916.2 0.252 12-May R.EYLYFLK.H sp|Q8N1N4|K2C78_HUMAN 1 974.5113 14.38 42215 18916 2 974.512865 488.2629 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 6.1 3623.7 - 3.65E+06 - - - 1.5854 - 1.062 0.32 - 100.6 1 2 0 0.0015 7 0 0 0 4.18E+07 2.90E+06 - - - 1.5946 1 230117_WJC_METTL3_WT_vs_EV_F05.18917.18917.2 2.14E-06 15/20 M.PPYTVVYFPVR.G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1336.718 1.16 42216 18917 2 1336.720196 669.3663 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3623.9 - 1.07E+06 - - - 1.6735 - 2.873 0.539 - 1118.3 1 2 0 0.0022 11 0 0 0 6.96E+07 5.99E+07 - - - 5.8763 1 230117_WJC_METTL3_WT_vs_EV_F05.18918.18918.2 1.92E-05 18-Nov K.C[160.03]LEEFELLGK[136.11].A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1244.6202 0.97 42217 18918 2 1244.618417 623.3174 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3623.9 - 943187 - - - -1.4527 - 2.16 0.505 - 325.2 1 2 0 -0.0018 10 0 0 0 1.11E+07 1.14E+07 - - - 4.92 0.919 230117_WJC_METTL3_WT_vs_EV_F05.18919.18919.2 6.46 14-Jun R.VPNAEEIF.- "sp|Q9BW92|SYTM_HUMAN,tr|F6S7Q7|F6S7Q7_HUMAN,tr|U3KQG0|U3KQG0_HUMAN" 3 917.4494 - 42218 18919 2 917.450196 459.732 "Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1" 3.79 3624.1 - 982990 - - - 0.8153 - 0.91 0.05 - 96.9 1 2 0 0.0007 8 0 0 0 - - - - - -0.8744 1 230117_WJC_METTL3_WT_vs_EV_F05.18923.18923.2 6.64E-07 17/20 M.PPYTVVYFPVR[166.11].G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1346.7262 1.13 42221 18923 2 1346.729364 674.3704 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3624.5 - 1.53E+06 - - - 2.3279 - 3.157 0.517 - 1610.6 1 2 0 0.0031 11 0 0 0 6.96E+07 6.15E+07 - - - 5.9686 1 230117_WJC_METTL3_WT_vs_EV_F05.18925.18925.2 0.000562 20-Nov K.MALDIEIATYR.K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1294.6591 1.38 42222 18925 2 1294.668115 648.3368 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3624.7 - 752392 - - - 6.9455 - 2.473 0.482 - 370.5 1 2 0 0.009 11 0 0 0 8.95E+07 6.48E+07 - - - 5.0476 0.9861 230117_WJC_METTL3_WT_vs_EV_F05.18929.18929.3 0.0271 Aug-36 K.SAEFLLHMLK.N "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 1187.6373 0.66 42226 18929 3 1187.635975 396.8864 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 6.47 3625.1 - 75472 - - - -1.087 - 1.427 0.212 - 66.2 1 2 0 -0.0013 10 0 0 0 1.52E+06 2.30E+06 - - - 1.9417 0.9896 230117_WJC_METTL3_WT_vs_EV_F05.18931.18931.2 6.71 18-Jul K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.23 42227 18931 2 1086.644901 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3625.3 - 530508 - - - 1.0767 - 1.204 0.121 - 131.9 1 2 0 0.0012 10 0 0 0 4.19E+08 3.41E+08 - - - 0.4525 1 230117_WJC_METTL3_WT_vs_EV_F05.18933.18933.2 8.73E-06 18-Oct K.GIFLGDDEWR.E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1206.5669 1.63 42229 18933 2 1206.569041 604.2907 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3625.5 - 668334 - - - 1.7438 - 2.151 0.48 - 337.1 1 2 0 0.0021 10 0 0 0 2.38E+07 1.46E+07 - - - 4.7236 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.18934.18934.2 0.252 16-Aug K.VQWGVFVPR.D sp|Q8IWA0|WDR75_HUMAN 1 1086.5974 1.28 42230 18934 2 1086.599439 544.306 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 9.72 3625.6 - 530508 - - - 1.8305 - 1.401 0.174 - 136.9 1 2 0 0.002 9 0 0 0 1.54E+07 1.20E+07 - - - 1.301 0.9746 230117_WJC_METTL3_WT_vs_EV_F05.18936.18936.2 0.505 16-Aug R.LLIDEAILK.C "sp|P49591|SYSC_HUMAN,tr|Q5T5C7|Q5T5C7_HUMAN" 2 1026.6325 1.63 42232 18936 2 1026.63075 514.3235 "Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3" 4.37 3625.8 - 285836 - - - -1.7027 - 1.376 0.117 - 145.3 1 2 0 -0.0017 9 0 0 0 1.33E+07 8.19E+06 - - - 0.828 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.18937.18937.3 0.00289 Oct-36 R.DFLLK[136.11]PELLR[166.11].A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1260.7561 1.18 42233 18937 3 1260.75842 421.2593 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3625.9 - 207087 - - - 1.8568 - 2.075 0.465 - 111.8 1 2 0 0.0023 10 0 0 0 2.94E+07 2.48E+07 - - - 5.8554 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18942.18942.2 0.0592 14-Sep K.LLQQLFLK.A sp|Q9P287|BCCIP_HUMAN 1 1001.6274 1.36 42236 18942 2 1001.629209 501.821 BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1 8.75 3626.6 - 2.83E+06 - - - 1.853 - 1.798 0.315 - 203.9 1 2 0 0.0019 8 0 0 0 2.37E+07 1.74E+07 - - - 3.1364 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.18943.18943.2 0.0269 18-Jul K.LLLGDLAPVR.G sp|Q9NUQ8|ABCF3_HUMAN 1 1065.6546 3.27 42237 18943 2 1065.656045 533.8346 ATP-binding cassette sub-family F member 3 OS=Homo sapiens OX=9606 GN=ABCF3 PE=1 SV=2 5.84 3626.6 - 1.33E+06 - - - 1.3278 - 1.53 0.213 - 120.8 1 2 0 0.0014 10 0 0 0 1.35E+07 4.14E+06 - - - 1.8008 1 230117_WJC_METTL3_WT_vs_EV_F05.18944.18944.2 9.00E-06 18-Oct K.GIFLGDDEWR[166.11].E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1216.5752 1.63 42238 18944 2 1216.577044 609.2949 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3626.7 - 2.43E+06 - - - 1.51 - 2.16 0.532 - 345.7 1 2 0 0.0018 10 0 0 0 2.38E+07 1.46E+07 - - - 5.1194 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18945.18945.2 0.0394 14-Aug K.LLQQLFLK[136.11].A sp|Q9P287|BCCIP_HUMAN 1 1009.6416 1.36 42239 18945 2 1009.643133 505.8281 BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1 8.75 3626.8 - 2.02E+06 - - - 1.5649 - 1.627 0.329 - 165.1 1 2 0 0.0016 8 0 0 0 2.37E+07 1.74E+07 - - - 2.9385 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.18949.18949.2 0.123 16-May K.VQWGVFVPR[166.11].D sp|Q8IWA0|WDR75_HUMAN 1 1096.6057 1.29 42243 18949 2 1096.606573 549.3101 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 9.72 3627.1 - 1.56E+06 - - - 0.7779 - 1.274 0.298 - 98.8 1 2 0 0.0009 9 0 0 0 1.79E+07 1.38E+07 - - - 1.9423 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.18950.18950.3 0.0199 Aug-36 R.DFLLKPELLR.A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1242.7336 1.18 42244 18950 3 1242.735933 415.2518 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3627.1 - 1.32E+06 - - - 1.8701 - 1.626 0.42 - 73.1 1 2 0 0.0023 10 0 0 0 2.93E+07 2.48E+07 - - - 4.6416 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.18951.18951.2 0.00122 14-Sep K.LGTLFAFK[136.11].K sp|Q6F5E8|CARL2_HUMAN 1 903.5309 3.71 42245 18951 2 903.535134 452.7727 "Capping protein, Arp2\3 and myosin-I linker protein 2 OS=Homo sapiens OX=9606 GN=CARMIL2 PE=1 SV=2" 8.75 3627.3 - 1.13E+06 - - - 4.6418 - 1.797 0.334 - 175.8 1 2 0 0.0042 8 0 0 0 2.01E+07 5.42E+06 - - - 3.2743 0.998 230117_WJC_METTL3_WT_vs_EV_F05.18953.18953.2 0.0111 18-Oct R.LFDQAFGLPR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1162.6135 0.5 42247 18953 2 1162.619418 582.314 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3627.5 - 507457 - - - 5.0954 - 2.242 0.426 - 363.9 1 2 0 0.0059 10 0 0 0 2.50E+06 4.97E+06 - - - 4.4392 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.18958.18958.2 0.00101 18-Aug R.LLLDTLQLSK.- "sp|O15357|SHIP2_HUMAN,tr|H7BXR2|H7BXR2_HUMAN" 2 1142.6911 2.27 42252 18958 2 1142.692915 572.3528 "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 OS=Homo sapiens OX=9606 GN=INPPL1 PE=1 SV=2" 5.84 3628.1 - 213623 - - - 1.6102 - 1.591 0.359 - 127.3 1 2 0 0.0018 10 0 0 0 5.45E+06 2.41E+06 - - - 2.9882 1 230117_WJC_METTL3_WT_vs_EV_F05.18960.18960.2 0.00118 14/24 R.ILLAEVPTMAVEK.V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1412.7949 5.92 42253 18960 2 1412.796637 707.4047 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3628.3 - 3.10E+06 - - - 1.2373 - 2.514 0.475 - 596.1 1 2 0 0.0017 13 0 0 0 5.28E+07 8.91E+06 - - - 4.9148 1 230117_WJC_METTL3_WT_vs_EV_F05.18961.18961.2 8.85E-06 20-Dec K.MALDIEIATYR[166.11].K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1304.6674 1.38 42254 18961 2 1304.669883 653.341 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3628.4 - 5.31E+06 - - - 1.9085 - 2.66 0.55 - 679.8 1 2 0 0.0025 11 0 0 0 8.96E+07 6.48E+07 - - - 5.7491 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18962.18962.2 3.72E-06 18-Oct K.TIC[160.03]AEFAILR.M "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1192.6274 0.45 42255 18962 2 1192.630059 597.321 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.66 3628.4 - 1.44E+06 - - - 2.2052 - 1.91 0.497 - 314 1 2 0 0.0026 10 0 0 0 1.75E+07 3.88E+07 - - - 4.5173 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18963.18963.2 0.00563 16-Jul K.ASSLISLLK.Q "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 930.575 2.35 42256 18963 2 930.57612 466.2948 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.8 3628.5 - 1.04E+06 - - - 1.2218 - 1.694 0.376 - 184.8 1 2 0 0.0011 9 0 0 0 3.20E+07 1.36E+07 - - - 3.3427 0.996 230117_WJC_METTL3_WT_vs_EV_F05.18964.18964.2 0.244 16-Sep R.LLIDEAILK[136.11].C "sp|P49591|SYSC_HUMAN,tr|Q5T5C7|Q5T5C7_HUMAN" 2 1034.6467 1.63 42257 18964 2 1034.648349 518.3306 "Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3" 4.37 3628.6 - 946424 - - - 1.5957 - 1.495 0.129 - 153.7 1 2 0 0.0017 9 0 0 0 1.33E+07 8.19E+06 - - - 1.1566 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.18969.18969.2 2.26E-06 16-Oct K.MC[160.03]LFAGFQR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1128.5209 0.91 42261 18969 2 1128.524667 565.2677 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3629.2 - 1.17E+06 - - - 3.377 - 2.102 0.383 - 459.3 1 2 0 0.0038 9 0 0 0 1.06E+08 1.17E+08 - - - 4.0179 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.18970.18970.2 0.02 16-Sep K.FALNSLLQR[166.11].Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1070.6112 2.1 42262 18970 2 1070.614762 536.3129 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.75 3629.4 - 325850 - - - 3.328 - 1.908 0.388 - 316.8 1 2 0 0.0036 9 0 0 0 4.65E+07 2.21E+07 - - - 3.7747 0.9084 230117_WJC_METTL3_WT_vs_EV_F05.18973.18973.3 1.63 Jul-36 K.FLPFSFEHIR[166.11].E "sp|Q93050|VPP1_HUMAN,tr|F5H1T6|F5H1T6_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 4 1301.6796 1.48 42265 18973 3 1301.684761 434.9005 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 6.75 3629.8 - 143078 - - - 3.9549 - 1.3 0.133 - 54 1 2 0 0.0051 10 0 0 0 2.21E+06 1.50E+06 - - - 0.7876 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.18974.18974.3 0.0288 Oct-40 R.FPFLGVHFTPR.M "sp|Q9H9P8|L2HDH_HUMAN,tr|C9JVN9|C9JVN9_HUMAN" 2 1316.703 0.46 42266 18974 3 1316.706244 439.9083 "L-2-hydroxyglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=L2HGDH PE=1 SV=3" 9.76 3629.9 - 140829 - - - 2.4812 - 2.287 0.33 - 77.2 1 2 0 0.0033 11 0 0 0 8.05E+05 1.75E+06 - - - 4.5683 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.18978.18978.2 6.34E-06 20-Oct R.FLMSLVNQVPK.L "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 1274.7057 1.12 42268 18978 2 1274.711431 638.3601 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 8.75 3630.5 - 640502 - - - 4.5116 - 1.954 0.347 - 211.8 1 2 0 0.0058 11 0 0 0 4.73E+07 4.22E+07 - - - 3.4143 0.9853 230117_WJC_METTL3_WT_vs_EV_F05.18979.18979.2 0.00258 16-Oct K.IIDGLLVMR[166.11].K "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1038.6135 3.34 42269 18979 2 1038.618845 520.314 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.84 3630.6 - 550042 - - - 5.1395 - 1.804 0.136 - 261.1 1 2 0 0.0053 9 0 0 0 1.15E+08 3.45E+07 - - - 1.7507 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.18980.18980.2 0.000442 18-Sep R.DFLLKPELLR.A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1242.7336 1.75 42270 18980 2 1242.735931 622.3741 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3630.8 - 422244 - - - 1.8685 - 1.814 0.41 - 345.1 1 2 0 0.0023 10 0 0 0 8.12E+06 4.63E+06 - - - 3.7308 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.18982.18982.2 0.288 18-Sep R.LLLDTLQLSK[136.11].- "sp|O15357|SHIP2_HUMAN,tr|H7BXR2|H7BXR2_HUMAN" 2 1150.7053 2.45 42272 18982 2 1150.708411 576.3599 "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 OS=Homo sapiens OX=9606 GN=INPPL1 PE=1 SV=2" 5.84 3631 - 198198 - - - 2.7253 - 1.501 0.22 - 139.1 1 2 0 0.0031 10 0 0 0 5.45E+06 2.23E+06 - - - 1.7986 1 230117_WJC_METTL3_WT_vs_EV_F05.18983.18983.2 4.44E-09 26-Dec R.FIAVGYVDDTQFVR.F "sp|P04439|HLAA_HUMAN,tr|A0A140T953|A0A140T953_HUMAN,tr|A0A140T941|A0A140T941_HUMAN,tr|A0A1W2PQS8|A0A1W2PQS8_HUMAN,tr|A0A0G2JI36|A0A0G2JI36_HUMAN,tr|A0A140T8W8|A0A140T8W8_HUMAN,tr|Q9GJ45|Q9GJ45_HUMAN,tr|Q53Z42|Q53Z42_HUMAN,tr|Q5RJ27|Q5RJ27_HUMAN,tr|Q53YP1|Q53YP1_HUMAN,tr|Q5SRN5|Q5SRN5_HUMAN,tr|A0A1W2PS24|A0A1W2PS24_HUMAN,tr|A0A0G2JIF2|A0A0G2JIF2_HUMAN,tr|A0A1W2PQD0|A0A1W2PQD0_HUMAN,tr|A0A1W2PRZ0|A0A1W2PRZ0_HUMAN,tr|A0A140T9U0|A0A140T9U0_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A0G2JPD3|A0A0G2JPD3_HUMAN,tr|A0A140T9W2|A0A140T9W2_HUMAN,tr|O78179|O78179_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|A0A1W2PPQ2|A0A1W2PPQ2_HUMAN,tr|A0A140T9T1|A0A140T9T1_HUMAN,tr|Q5SPM2|Q5SPM2_HUMAN,tr|Q5SUL5|Q5SUL5_HUMAN,tr|A0A140T8Y4|A0A140T8Y4_HUMAN,tr|A0A140T975|A0A140T975_HUMAN,tr|A0A140TA03|A0A140TA03_HUMAN,tr|A0A140TA13|A0A140TA13_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A1W2PSE7|A0A1W2PSE7_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|A0A1W2PPF8|A0A1W2PPF8_HUMAN,tr|D9J307|D9J307_HUMAN,tr|A0A140T937|A0A140T937_HUMAN,tr|Q5SRN7|Q5SRN7_HUMAN,tr|A0A1W2PR61|A0A1W2PR61_HUMAN,tr|A0A140T912|A0A140T912_HUMAN,tr|A0A140T9M0|A0A140T9M0_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN,tr|A0A1W2PS39|A0A1W2PS39_HUMAN,tr|A0A140T9Z6|A0A140T9Z6_HUMAN,tr|A0A140T9M5|A0A140T9M5_HUMAN,tr|A0A140T930|A0A140T930_HUMAN,tr|A0A140T9Z4|A0A140T9Z4_HUMAN,tr|B0UXQ0|B0UXQ0_HUMAN,tr|A0A0G2JL56|A0A0G2JL56_HUMAN" 48 1628.8199 6.04 42273 18983 2 1628.827851 815.4172 "HLA class I histocompatibility antigen, A alpha chain OS=Homo sapiens OX=9606 GN=HLA-A PE=1 SV=2" 4.21 3631.2 - 156903 - - - 4.9072 - 2.617 0.647 - 452.2 1 2 0 0.008 14 0 0 0 4.43E+06 7.34E+05 - - - 6.2314 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.18988.18988.2 0.00625 18-Aug R.LEPVIMELER[166.11].Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1237.6616 0.67 42277 18988 2 1237.665697 619.8381 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3631.8 - 542985 - - - 3.3264 - 1.648 0.373 - 277.9 1 2 0 0.0041 10 0 0 0 7.15E+07 1.06E+08 - - - 3.1891 1 230117_WJC_METTL3_WT_vs_EV_F05.18990.18990.2 0.193 18-Sep R.LFDQAFGLPR[166.11].L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1172.6218 1.22 42279 18990 2 1172.624822 587.3182 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3631.9 - 4.56E+06 - - - 2.6078 - 2.107 0.471 - 287.2 1 2 0 0.0031 10 0 0 0 6.16E+08 5.06E+08 - - - 4.5991 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.18994.18994.2 0.0343 16-Aug K.DIVENYFMR.D "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN" 2 1185.5488 1.08 42283 18994 2 1185.549944 593.7817 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.37 3632.1 - 221070 - - - 0.927 - 1.432 0.271 - 206.4 1 2 0 0.0011 9 0 0 0 8.82E+06 8.14E+06 - - - 2.0811 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.18997.18997.2 0.206 14-Aug R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 3.16 42286 18997 2 1000.56132 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3632.4 - 120193 - - - 1.9859 - 1.57 0.267 - 184.7 1 2 0 0.002 8 0 0 0 2.22E+07 7.03E+06 - - - 2.3729 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.18999.18999.2 0.00906 14-Sep R.LSFAVPFR.E sp|P78527|PRKDC_HUMAN 1 935.5229 1.11 42287 18999 2 935.524683 468.7687 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3632.6 - 2.30E+06 - - - 1.9187 - 2.031 0.296 - 266.6 1 2 0 0.0018 8 0 0 0 3.05E+07 2.75E+07 - - - 3.3636 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.19001.19001.2 0.000232 16-Sep K.MC[160.03]LFAGFQR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1138.5291 0.91 42288 19001 2 1138.533918 570.2718 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3632.8 - 3.70E+06 - - - 4.2089 - 1.967 0.298 - 477 1 2 0 0.0048 9 0 0 0 1.06E+08 1.17E+08 - - - 3.1977 1 230117_WJC_METTL3_WT_vs_EV_F05.19002.19002.2 1.18E-05 18-Oct R.LMALLGQALK[136.11].W sp|Q2TAY7|SMU1_HUMAN 1 1064.6507 1.01 42289 19002 2 1064.654993 533.3326 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.75 3632.9 - 1.01E+06 - - - 3.9976 - 1.979 0.495 - 364.1 1 2 0 0.0043 10 0 0 0 3.39E+07 3.37E+07 - - - 4.6011 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.19003.19003.2 0.027 14-Jun R.LSFAVPFR[166.11].E sp|P78527|PRKDC_HUMAN 1 945.5312 1.14 42290 19003 2 945.532389 473.7729 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3632.9 - 1.09E+06 - - - 1.3019 - 1.545 0.322 - 143 1 2 0 0.0012 8 0 0 0 3.13E+07 2.75E+07 - - - 2.7309 0.9943 230117_WJC_METTL3_WT_vs_EV_F05.19005.19005.2 0.0488 14-Jul K.LDFNWVTR.W "sp|Q86W92|LIPB1_HUMAN,tr|F5GZP6|F5GZP6_HUMAN" 2 1049.5294 1.27 42292 19005 2 1049.535195 525.772 Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2 5.84 3633.1 - 93364.7 - - - 5.4929 - 1.439 0.39 - 123 1 2 0 0.0058 8 0 0 0 4.46E+06 3.50E+06 - - - 3.0174 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19012.19012.2 0.00928 18-Jul R.DFLLK[136.11]PELLR[166.11].A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1260.7561 1.78 42297 19012 2 1260.757454 631.3853 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3633.9 - 134553 - - - 1.0906 - 1.631 0.396 - 203.9 1 2 0 0.0014 10 0 0 0 8.23E+06 4.63E+06 - - - 3.3309 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.19013.19013.2 0.0735 20-Sep K.GPILMELQTYR.Y "sp|P08559|ODPA_HUMAN,sp|P29803|ODPAT_HUMAN" 2 1319.6908 2.2 42298 19013 2 1319.695502 660.8527 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 6 3634.1 - 0 - - - 3.5948 - 1.615 0.302 - 65 1 2 0 0.0047 11 0 0 0 7.87E+06 3.58E+06 - - - 2.5668 0.985 230117_WJC_METTL3_WT_vs_EV_F05.19015.19015.2 0.784 24-Apr R.LLPPEDTQELIFK[136.11].D sp|O60287|NPA1P_HUMAN 1 1549.8483 1.54 42300 19015 2 1549.850062 775.9314 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 4.14 3634.3 - 0 - - - 1.1298 - 1.045 0.178 - 35.4 4 2 0 0.0018 13 0 0 0 3.97E+06 2.59E+06 - - - 0.1992 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.19021.19021.2 0.00157 14-Aug R.IPLNDLFR.C sp|P13473|LAMP2_HUMAN 1 986.5549 9.02 42305 19021 2 986.555111 494.2847 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3635.1 - 9.02E+06 - - - 0.1977 - 1.849 0.261 - 310.7 1 2 0 0.0002 8 0 0 0 1.28E+08 1.42E+07 - - - 2.8224 0.9954 230117_WJC_METTL3_WT_vs_EV_F05.19028.19028.2 6.08E-05 18-Sep R.LYDVVAVFPK[136.11].T "sp|P78346|RPP30_HUMAN,tr|Q5VU11|Q5VU11_HUMAN,tr|Q5VU10|Q5VU10_HUMAN" 3 1157.6576 1.29 42311 19028 2 1157.664575 579.8361 Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1 5.83 3635.9 - 417647 - - - 6.0277 - 1.938 0.411 - 168.9 1 2 0 0.007 10 0 0 0 2.03E+07 1.57E+07 - - - 3.9213 0.999 230117_WJC_METTL3_WT_vs_EV_F05.19030.19030.2 0.00299 24-Jul R.LLPPEDTQELIFK.D sp|O60287|NPA1P_HUMAN 1 1541.8341 1.32 42313 19030 2 1541.833983 771.9243 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 4.14 3636.2 - 155468 - - - -0.083 - 1.567 0.358 - 106.3 1 2 0 -0.0001 13 0 0 0 2.39E+06 1.80E+06 - - - 2.8379 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.19034.19034.2 0.105 16-Aug R.LQLPVWEYK[136.11].D sp|O43143|DHX15_HUMAN 1 1182.6528 1.81 42315 19034 2 1182.656437 592.3337 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 3636.6 - 3.61E+06 - - - 3.0364 - 1.637 0.303 - 229.7 1 2 0 0.0036 9 0 0 0 8.28E+07 4.56E+07 - - - 2.7037 0.9861 230117_WJC_METTL3_WT_vs_EV_F05.19035.19035.2 0.00453 18-Jul R.LYDVVAVFPK.T "sp|P78346|RPP30_HUMAN,tr|Q5VU11|Q5VU11_HUMAN,tr|Q5VU10|Q5VU10_HUMAN" 3 1149.6434 1.12 42316 19035 2 1149.651842 575.829 Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1 5.83 3636.7 - 1.39E+06 - - - 7.3458 - 1.532 0.428 - 122.4 1 2 0 0.0084 10 0 0 0 2.05E+07 1.83E+07 - - - 3.3903 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.19037.19037.2 0.129 14-Jun R.IPLNDLFR[166.11].C sp|P13473|LAMP2_HUMAN 1 996.5632 9.7 42318 19037 2 996.565266 499.2889 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3636.8 - 1.24E+06 - - - 2.0872 - 1.326 0.233 - 96.7 1 2 0 0.0021 8 0 0 0 1.27E+08 1.31E+07 - - - 1.6123 0.966 230117_WJC_METTL3_WT_vs_EV_F05.19045.19045.2 0.722 16-Aug K.SGILPILVK.C sp|O00505|IMA4_HUMAN 1 938.6165 1.36 42324 19045 2 938.622681 470.3155 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3637.8 - 329264 - - - 6.6342 - 1.325 0.274 - 152.5 1 2 0 0.0062 9 0 0 0 3.42E+07 2.52E+07 - - - 1.877 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.19053.19053.2 0.0927 14-Aug R.FYTIEILK.V sp|P12273|PIP_HUMAN 1 1025.5797 69.91 42331 19053 2 1025.582029 513.7971 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 6 3638.8 - 6.15E+06 - - - 2.2378 - 1.625 0.244 - 171.4 1 2 0 0.0023 8 0 0 0 3.47E+08 4.96E+06 - - - 2.3067 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.19055.19055.2 0.0786 16-Sep K.SGILPILVK[136.11].C sp|O00505|IMA4_HUMAN 1 946.6307 1.36 42332 19055 2 946.634187 474.3226 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3639 - 1.73E+06 - - - 3.7322 - 1.466 0.407 - 185.4 1 2 0 0.0035 9 0 0 0 3.42E+07 2.52E+07 - - - 3.1527 0.9882 230117_WJC_METTL3_WT_vs_EV_F05.19057.19057.2 1.32 14-Jul R.VLLLPLER.D sp|O95071|UBR5_HUMAN 1 951.6117 1.62 42334 19057 2 951.614355 476.8131 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3639.2 - 985441 - - - 2.7869 - 1.462 0.069 - 165.9 1 2 0 0.0027 8 0 0 0 1.88E+07 1.16E+07 - - - 0.6953 0.9913 230117_WJC_METTL3_WT_vs_EV_F05.19058.19058.2 2.74 14-Jun R.VLLLPLER[166.11].D sp|O95071|UBR5_HUMAN 1 961.62 1.56 42335 19058 2 961.623489 481.8173 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3639.4 - 631998 - - - 3.6563 - 1.393 0.176 - 104.2 1 2 0 0.0035 8 0 0 0 1.88E+07 1.21E+07 - - - 1.3395 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.19064.19064.2 0.000327 13/24 R.ALGLGLVSPAQLR.V "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|A8MRA7|A8MRA7_HUMAN" 3 1293.7769 3.02 42341 19064 2 1293.78019 647.8957 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 9.79 3640.1 - 182142 - - - 2.5654 - 2.789 0.225 - 736.9 1 2 0 0.0033 13 0 0 0 5.68E+06 1.88E+06 - - - 3.3343 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19068.19068.2 0.000199 18-Sep R.LEPVIMELER.Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1227.6533 0.54 42344 19068 2 1227.655887 614.8339 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3640.6 - 1.56E+06 - - - 2.0991 - 1.845 0.374 - 383.3 1 2 0 0.0026 10 0 0 0 5.58E+07 1.04E+08 - - - 3.5122 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.19071.19071.2 0.136 14-Sep K.MIDLIIPR.G sp|P54886|P5CS_HUMAN 1 969.5681 1.75 42346 19071 2 969.57084 485.7913 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 5.59 3641 - 373065 - - - 2.8023 - 1.817 0.21 - 305.6 1 2 0 0.0027 8 0 0 0 8.14E+06 4.66E+06 - - - 2.3923 0.9883 230117_WJC_METTL3_WT_vs_EV_F05.19072.19072.2 0.0155 12-Aug R.IQLLVFK[136.11].H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 867.5673 0.69 42347 19072 2 867.571055 434.7909 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3641.1 - 287951 - - - 4.2994 - 1.768 0.082 - 176.3 1 2 0 0.0037 7 0 0 0 1.69E+07 2.46E+07 - - - 1.4511 0.9934 230117_WJC_METTL3_WT_vs_EV_F05.19074.19074.2 0.0387 12-Jul R.GLLEYFK[136.11].A "sp|Q6DD88|ATLA3_HUMAN,tr|F5H6I7|F5H6I7_HUMAN" 2 876.4837 1.77 42349 19074 2 876.48795 439.2491 Atlastin-3 OS=Homo sapiens OX=9606 GN=ATL3 PE=1 SV=1 6 3641.4 - 200011 - - - 4.9003 - 1.478 0.284 - 137.7 1 2 0 0.0043 7 0 0 0 3.71E+06 2.09E+06 - - - 2.3752 1 230117_WJC_METTL3_WT_vs_EV_F05.19076.19076.2 3.10E-07 24-Nov R.LLPGEEC[160.03]VLDGLR.V sp|O95248|MTMR5_HUMAN 1 1469.7548 1.32 42351 19076 2 1469.758899 735.8847 Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4 4.14 3641.6 - 128208 - - - 2.7787 - 2.262 0.601 - 403.4 1 2 0 0.0041 13 0 0 0 2.90E+06 2.19E+06 - - - 5.5736 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.19079.19079.2 7.49E-07 22-Oct K.GALPLDTVTFYK.V sp|P30040|ERP29_HUMAN 1 1323.7075 1.41 42353 19079 2 1323.714116 662.861 Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4 5.83 3642 - 764249 - - - 5.0328 - 1.984 0.504 - 378.5 1 2 0 0.0067 12 0 0 0 5.32E+06 3.78E+06 - - - 4.5641 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.19082.19082.2 0.0182 18-Nov K.SVVTSIFGVK.N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1035.5964 1.75 42355 19082 2 1035.60184 518.8055 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3642.3 - 1.85E+06 - - - 5.2076 - 2.113 0.352 - 323.2 1 2 0 0.0054 10 0 0 0 2.67E+07 1.53E+07 - - - 3.7274 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.19084.19084.2 0.0574 14-Sep K.GLLQLQWK[136.11].Q sp|O94826|TOM70_HUMAN 1 992.5899 1.19 42357 19084 2 992.593746 497.3022 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.75 3642.4 - 1.41E+06 - - - 3.9231 - 1.699 0.213 - 237.8 1 2 0 0.0039 8 0 0 0 1.04E+07 8.71E+06 - - - 2.2116 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19085.19085.2 5.26E-05 18-Sep K.SVVTSIFGVK[136.11].N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1043.6106 1.67 42358 19085 2 1043.614295 522.8126 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3642.5 - 997180 - - - 3.4956 - 1.942 0.405 - 211.7 1 2 0 0.0036 10 0 0 0 2.67E+07 1.60E+07 - - - 3.8838 0.9918 230117_WJC_METTL3_WT_vs_EV_F05.19086.19086.2 0.0531 12-Jul R.IQLLVFK.H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 859.5531 0.69 42359 19086 2 859.55608 430.7838 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3642.7 - 809104 - - - 3.4378 - 1.587 0.104 - 152.5 1 2 0 0.003 7 0 0 0 1.69E+07 2.47E+07 - - - 1.2716 0.9956 230117_WJC_METTL3_WT_vs_EV_F05.19088.19088.2 0.849 14-Aug R.AENFFILR.R "sp|P59998|ARPC4_HUMAN,tr|A0A0A6YYG9|A0A0A6YYG9_HUMAN,tr|F8WCF6|F8WCF6_HUMAN,tr|F8WDD7|F8WDD7_HUMAN,tr|R4GN08|R4GN08_HUMAN" 5 1008.5393 2.09 42361 19088 2 1008.542438 505.2769 Actin-related protein 2\3 complex subunit 4 OS=Homo sapiens OX=9606 GN=ARPC4 PE=1 SV=3 6.05 3642.9 - 703210 - - - 3.1451 - 1.7 0.136 - 254.6 1 2 0 0.0032 8 0 0 0 5.43E+06 2.59E+06 - - - 1.6449 1 230117_WJC_METTL3_WT_vs_EV_F05.19092.19092.2 3.17E-05 15/32 R.AAVEEGIVLGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1683.8978 2.29 42365 19092 2 1683.905905 842.9562 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3643.4 - 291121 - - - 4.8186 - 2.975 0.429 - 580.7 1 2 0 0.0081 17 0 0 0 9.71E+05 4.24E+05 - - - 4.8875 0.9917 230117_WJC_METTL3_WT_vs_EV_F05.19095.19095.2 0.0625 18-Jul R.FEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1252.6088 999 42368 19095 2 1252.607666 627.3117 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3643.8 - 289519 - - - -0.9069 - 1.237 0.227 - 123.5 1 2 0 -0.0011 10 0 0 0 1.82E+06 0.00E+00 - - - 1.3109 0.9969 230117_WJC_METTL3_WT_vs_EV_F05.19102.19102.2 0.00931 14-Aug K.MIDLIIPR[166.11].G sp|P54886|P5CS_HUMAN 1 979.5764 1.79 42374 19102 2 979.580671 490.7955 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 5.59 3644.7 - 482281 - - - 4.3672 - 1.7 0.31 - 195.3 2 2 0 0.0043 8 0 0 0 8.13E+06 4.53E+06 - - - 2.7952 0.99 230117_WJC_METTL3_WT_vs_EV_F05.19103.19103.2 0.109 12-Jun R.DYLQLLR[166.11].K sp|L0R6Q1|S35U4_HUMAN 1 929.521 1.61 42375 19103 2 929.524786 465.7678 SLC35A4 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=SLC35A4 PE=3 SV=1 5.84 3644.8 - 635561 - - - 4.0871 - 1.275 0.224 - 160.7 1 2 0 0.0038 7 0 0 0 7.53E+06 4.68E+06 - - - 1.4641 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.19104.19104.2 0.00519 16-Aug K.LLIYWASTR.E sp|P06312|KV401_HUMAN 1 1121.6233 172.38 42376 19104 2 1121.627171 561.8189 Immunoglobulin kappa variable 4-1 OS=Homo sapiens OX=9606 GN=IGKV4-1 PE=1 SV=1 8.75 3644.9 - 2.84E+06 - - - 3.4245 - 1.861 0.337 - 252.3 1 2 0 0.0038 9 0 0 0 2.09E+07 1.21E+05 - - - 3.3258 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.19107.19107.2 0.000454 18-Aug K.SVPDEIILLR[166.11].S sp|Q9H9A6|LRC40_HUMAN 1 1163.6789 2.37 42379 19107 2 1163.682678 582.8467 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.37 3645.1 - 1.04E+06 - - - 3.2088 - 1.636 0.4 - 245.4 1 2 0 0.0037 10 0 0 0 2.55E+07 1.08E+07 - - - 3.3683 1 230117_WJC_METTL3_WT_vs_EV_F05.19108.19108.2 0.00206 14/22 K.LSTIALALGVER.T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1241.7343 1.95 42380 19108 2 1241.738819 621.8744 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3645.2 - 1.02E+06 - - - 3.6095 - 2.573 0.42 - 701.7 1 2 0 0.0045 12 0 0 0 3.23E+07 1.65E+07 - - - 4.6284 0.932 230117_WJC_METTL3_WT_vs_EV_F05.19109.19109.2 0.00923 24-Aug R.SYEAVAAAAASVY.N sp|Q9BWF3|RBM4_HUMAN 1 1271.6034 - 42381 19109 2 1271.606598 636.809 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4 3645.3 - 585213 - - - 2.5283 - 1.562 0.363 - 181.1 1 1 0 0.0032 13 0 0 0 - - - - - 2.8657 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.19110.19110.2 0.00258 13/22 K.LSTIALALGVER[166.11].T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1251.7426 1.96 42382 19110 2 1251.746994 626.8786 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3645.5 - 508056 - - - 3.5047 - 2.468 0.374 - 560.8 1 2 0 0.0044 12 0 0 0 3.24E+07 1.65E+07 - - - 4.179 1 230117_WJC_METTL3_WT_vs_EV_F05.19111.19111.2 1.58E-07 20-Nov R.FSTIEEFSYIR.R "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1390.6769 1.35 42383 19111 2 1390.685469 696.3457 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 4.53 3645.6 - 487632 - - - 6.1747 - 2.478 0.583 - 500.4 1 2 0 0.0086 11 0 0 0 3.79E+06 2.80E+06 - - - 5.7992 0.999 230117_WJC_METTL3_WT_vs_EV_F05.19112.19112.2 4.58E-06 20-Oct R.FSTIEEFSYIR[166.11].R "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1400.6852 1.35 42384 19112 2 1400.689995 701.3499 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 4.53 3645.7 - 362952 - - - 3.4576 - 1.887 0.377 - 284.5 1 2 0 0.0048 11 0 0 0 3.79E+06 2.80E+06 - - - 3.5418 1 230117_WJC_METTL3_WT_vs_EV_F05.19113.19113.2 5.70E-05 20-Dec K.LLEVQILEVQR.A "sp|Q8IWJ2|GCC2_HUMAN,tr|H7BYJ9|H7BYJ9_HUMAN" 2 1338.7871 1.13 42385 19113 2 1338.792819 670.4008 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.53 3645.9 - 272380 - - - 4.271 - 2.513 0.476 - 620.1 1 2 0 0.0057 11 0 0 0 1.44E+06 1.27E+06 - - - 5.0478 0.9941 230117_WJC_METTL3_WT_vs_EV_F05.19114.19114.2 0.0763 20-Jul K.ELFPIQMEGVK[136.11].L "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 1297.6832 0.91 42386 19114 2 1297.687621 649.8489 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.53 3646 - 263701 - - - 3.4377 - 1.386 0.22 - 126.3 1 2 0 0.0045 11 0 0 0 5.31E+06 5.81E+06 - - - 1.5476 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.19117.19117.2 0.147 24-Sep R.ALGLGLVSPAQLR[166.11].V "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|A8MRA7|A8MRA7_HUMAN" 3 1303.7851 3.02 42389 19117 2 1303.787961 652.8998 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 9.79 3646.4 - 178263 - - - 2.1629 - 1.815 0.179 - 234.5 1 2 0 0.0028 13 0 0 0 5.68E+06 1.88E+06 - - - 1.8921 1 230117_WJC_METTL3_WT_vs_EV_F05.19123.19123.2 1.04E-05 16-Nov R.QINWTVLYR.R "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1191.64 0.9 42394 19123 2 1191.64339 596.8273 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 8.75 3647.1 - 2.02E+06 - - - 2.8087 - 2.274 0.497 - 779 1 2 0 0.0033 9 0 0 0 3.51E+07 3.91E+07 - - - 5.0876 1 230117_WJC_METTL3_WT_vs_EV_F05.19126.19126.2 0.000507 14-Oct K.ILTPIIFK.E "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5L9|H7C5L9_HUMAN" 4 943.6106 0.66 42397 19126 2 943.612921 472.8126 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 8.75 3647.4 - 1.29E+06 - - - 2.4173 - 2.035 0.465 - 298.1 1 2 0 0.0023 8 0 0 0 1.28E+07 1.94E+07 - - - 4.6176 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19127.19127.2 2.85E-05 13/20 R.TSLALDESLFR[166.11].G "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|H0YJH9|H0YJH9_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 5 1260.6589 1.2 42398 19127 2 1260.661425 631.3367 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.37 3647.5 - 889824 - - - 1.9736 - 2.757 0.319 - 924.5 1 2 0 0.0025 11 0 0 0 2.31E+07 1.92E+07 - - - 4.1398 1 230117_WJC_METTL3_WT_vs_EV_F05.19129.19129.2 8.71E-06 18-Nov R.LWIANYSLPR.A sp|O43172|PRP4_HUMAN 1 1231.6713 3.26 42400 19129 2 1231.673943 616.8429 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3647.7 - 550776 - - - 2.111 - 2.267 0.543 - 600.2 1 2 0 0.0026 10 0 0 0 1.04E+08 3.19E+07 - - - 5.3353 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.19132.19132.2 0.00026 20-Oct K.ELFPIQMEGVK.L "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 1289.669 0.91 42403 19132 2 1289.673601 645.8418 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.53 3648.1 - 373399 - - - 3.5986 - 1.805 0.333 - 306 1 2 0 0.0046 11 0 0 0 5.31E+06 5.81E+06 - - - 3.0967 0.999 230117_WJC_METTL3_WT_vs_EV_F05.19133.19133.2 0.0176 24-Sep K.FIAELGVPLSQVK.S sp|Q86T24|KAISO_HUMAN 1 1399.8075 5.83 42404 19133 2 1399.811382 700.911 Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2 6 3648.2 - 256822 - - - 2.7718 - 1.846 0.315 - 185.5 1 2 0 0.0039 13 0 0 0 1.96E+06 3.37E+05 - - - 2.9397 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.19134.19134.2 0.0612 14-Aug K.LAIVLFTK[136.11].E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 911.5935 1.87 42405 19134 2 911.595216 456.804 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3648.4 - 229725 - - - 1.8385 - 1.731 0.13 - 153.9 1 2 0 0.0017 8 0 0 0 3.88E+06 2.07E+06 - - - 1.6555 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.19141.19141.2 0.216 18-Oct R.IIVAIDGWPR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1138.6499 2.56 42410 19141 2 1138.652244 570.3322 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3649.2 - 7.60E+06 - - - 2.077 - 2.201 0.12 - 359.8 1 2 0 0.0024 10 0 0 0 7.67E+07 2.99E+07 - - - 2.1287 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.19142.19142.2 0.0121 16-Aug K.VFSIGPVFR[166.11].A sp|P14868|SYDC_HUMAN 1 1030.5839 1.08 42411 19142 2 1030.585476 516.2992 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3649.2 - 4.14E+06 - - - 1.5079 - 1.552 0.303 - 203.7 1 2 0 0.0016 9 0 0 0 4.11E+07 3.82E+07 - - - 2.5501 1 230117_WJC_METTL3_WT_vs_EV_F05.19144.19144.2 7.18E-07 16-Oct K.MDLVTYFGK.R sp|P09543|CN37_HUMAN 1 1072.5263 3.19 42413 19144 2 1072.527832 537.2704 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 5.59 3649.4 - 1.30E+06 - - - 1.4116 - 2.192 0.522 - 423.8 1 2 0 0.0015 9 0 0 0 1.29E+07 4.03E+06 - - - 5.1665 0.9757 230117_WJC_METTL3_WT_vs_EV_F05.19145.19145.2 1.94 12-Jun K.QFLDYFK.T "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 959.4753 1.51 42414 19145 2 959.476565 480.7449 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.83 3649.4 - 1.29E+06 - - - 1.3507 - 1.176 0.043 - 137 1 2 0 0.0013 7 0 0 0 7.99E+06 5.30E+06 - - - -0.1281 0.9793 230117_WJC_METTL3_WT_vs_EV_F05.19146.19146.2 0.238 12-Jun K.QFLDYFK[136.11].T "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 967.4895 1.49 42415 19146 2 967.490632 484.752 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.83 3649.5 - 632167 - - - 1.2021 - 1.234 0.037 - 128.2 1 2 0 0.0012 7 0 0 0 8.05E+06 5.41E+06 - - - -0.0199 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19147.19147.2 0.00435 18-Aug K.LLVLSALAEK.L sp|Q13395|TARB1_HUMAN 1 1055.659 1.52 42416 19147 2 1055.660144 528.8368 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6 3649.7 - 597281 - - - 1.0392 - 1.746 0.402 - 137.6 1 2 0 0.0011 10 0 0 0 4.61E+06 3.03E+06 - - - 3.5655 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.19148.19148.2 0.701 14-Oct K.LAIVLFTK.E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 903.5793 1.87 42417 19148 2 903.580703 452.7969 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3649.8 - 489979 - - - 1.5084 - 1.983 0.192 - 271.2 1 2 0 0.0014 8 0 0 0 3.88E+06 2.07E+06 - - - 2.5234 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19150.19150.2 0.000112 18-Aug K.ELPEYYELIR.K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1323.6711 1.75 42419 19150 2 1323.673587 662.8428 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3650 - 378532 - - - 1.903 - 2.009 0.47 - 288.9 1 2 0 0.0025 10 0 0 0 1.54E+07 8.82E+06 - - - 4.4589 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.19151.19151.2 0.00084 18-Aug K.ELPEYYELIR[166.11].K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1333.6793 1.75 42420 19151 2 1333.68238 667.8469 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3650.2 - 306374 - - - 2.2809 - 1.712 0.359 - 286.5 1 2 0 0.003 10 0 0 0 1.54E+07 8.82E+06 - - - 3.1924 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.19157.19157.2 0.0303 18-Sep R.IIVAIDGWPR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1148.6581 2.74 42425 19157 2 1148.66175 575.3364 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3651 - 4.24E+06 - - - 3.135 - 1.972 0.294 - 280.5 1 2 0 0.0036 10 0 0 0 8.20E+07 2.99E+07 - - - 3.1068 0.9864 230117_WJC_METTL3_WT_vs_EV_F05.19159.19159.2 0.00771 18-Aug R.LWIANYSLPR[166.11].A sp|O43172|PRP4_HUMAN 1 1241.6796 3.28 42426 19159 2 1241.686664 621.8471 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3651.3 - 7.24E+06 - - - 5.6786 - 1.89 0.183 - 197.9 1 2 0 0.0071 10 0 0 0 1.03E+08 3.16E+07 - - - 2.1673 1 230117_WJC_METTL3_WT_vs_EV_F05.19160.19160.2 0.00342 15/20 R.TSLALDESLFR.G "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|H0YJH9|H0YJH9_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 5 1250.6507 1.25 42427 19160 2 1250.655174 626.3326 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.37 3651.3 - 4.38E+06 - - - 3.6037 - 2.883 0.395 - 1111 1 2 0 0.0045 11 0 0 0 2.43E+07 1.95E+07 - - - 4.8214 1 230117_WJC_METTL3_WT_vs_EV_F05.19163.19163.2 0.00109 20-Dec R.GVIFTEAFVAR.H sp|O94874|UFL1_HUMAN 1 1208.6554 2.63 42430 19163 2 1208.661227 605.335 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 6 3651.7 - 1.35E+06 - - - 4.855 - 2.545 0.483 - 417.1 1 2 0 0.0059 11 0 0 0 8.43E+06 3.21E+06 - - - 5.1336 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.19168.19168.2 0.0224 16-Aug K.IFAFDLDAK[136.11].R sp|Q96P11|NSUN5_HUMAN 1 1046.5528 0.68 42435 19168 2 1046.55489 524.2837 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 4.21 3652.3 - 641033 - - - 1.9999 - 1.583 0.277 - 103.7 1 2 0 0.0021 9 0 0 0 7.53E+06 1.11E+07 - - - 2.4151 1 230117_WJC_METTL3_WT_vs_EV_F05.19170.19170.2 0.00123 22-Dec K.VLGTEELYGYLK[136.11].K "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1391.7428 1.02 42437 19170 2 1391.74772 696.8787 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.53 3652.6 - 373564 - - - 3.5474 - 2.292 0.497 - 327.8 1 2 0 0.0049 12 0 0 0 1.01E+07 9.91E+06 - - - 4.8926 1 230117_WJC_METTL3_WT_vs_EV_F05.19171.19171.2 0.12 22-Dec R.LC[160.03]LTDEEVVFVR.L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1478.7439 6.02 42438 19171 2 1478.743928 740.3792 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3652.7 - 351285 - - - 0.0081 - 2.658 0.492 - 620.7 1 2 0 0 12 0 0 0 5.57E+06 9.25E+05 - - - 5.2471 1 230117_WJC_METTL3_WT_vs_EV_F05.19172.19172.2 8.17E-07 22-Nov K.VLGTEELYGYLK.K "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1383.7286 1.02 42439 19172 2 1383.73596 692.8716 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.53 3652.8 - 318541 - - - 5.3312 - 2.419 0.569 - 294.8 1 2 0 0.0074 12 0 0 0 1.01E+07 9.91E+06 - - - 5.5656 1 230117_WJC_METTL3_WT_vs_EV_F05.19174.19174.2 1.30E-07 13/22 R.LC[160.03]LTDEEVVFVR[166.11].L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1488.7522 -1 42441 19174 2 1488.753816 745.3834 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3653.1 - 223206 - - - 1.0949 - 2.673 0.585 - 773.2 1 2 0 0.0016 12 0 0 0 0.00E+00 0.00E+00 - - - 5.9483 0.8959 230117_WJC_METTL3_WT_vs_EV_F05.19178.19178.2 0.0993 May-36 R.SSPAAFINPPIGTVTPALK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1888.0549 1.92 42445 19178 2 1888.06851 945.0348 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.47 3653.6 - 104369 - - - 7.182 - 1.158 0.237 - 42.2 1 2 0 0.0136 19 0 0 0 8.72E+05 4.54E+05 - - - 1.1479 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.19180.19180.2 0.000495 16-Oct K.VFSIGPVFR.A sp|P14868|SYDC_HUMAN 1 1020.5757 1.08 42446 19180 2 1020.580559 511.2951 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3653.9 - 2.00E+06 - - - 4.8081 - 1.829 0.376 - 407.7 1 2 0 0.0049 9 0 0 0 4.11E+07 3.82E+07 - - - 3.5633 1 230117_WJC_METTL3_WT_vs_EV_F05.19183.19183.2 5.55E-05 16-Oct K.ISVNDFIIK[136.11].A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1055.6106 0.7 42448 19183 2 1055.617018 528.8126 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 3654.1 - 678779 - - - 6.0354 - 2.165 0.453 - 211.3 1 2 0 0.0064 9 0 0 0 7.72E+06 1.10E+07 - - - 4.6195 1 230117_WJC_METTL3_WT_vs_EV_F05.19184.19184.2 7.24E-07 13/22 R.VVYSAFLMATPR.L sp|Q15029|U5S1_HUMAN 1 1353.7115 1.47 42449 19184 2 1353.713952 677.863 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.72 3654.2 - 718978 - - - 1.8165 - 2.544 0.553 - 594.2 1 2 0 0.0025 12 0 0 0 8.16E+06 5.54E+06 - - - 5.5815 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.19185.19185.2 0.000502 18-Sep R.SIPMTVDFIR.L sp|P00492|HPRT_HUMAN 1 1177.6165 1.93 42450 19185 2 1177.615791 589.8155 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 5.55 3654.3 - 593052 - - - -0.6275 - 1.93 0.449 - 366.6 1 2 0 -0.0007 10 0 0 0 1.36E+07 7.05E+06 - - - 4.1924 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19187.19187.2 0.000613 16-Sep K.IFAFDLDAK.R sp|Q96P11|NSUN5_HUMAN 1 1038.5386 0.73 42452 19187 2 1038.538072 520.2766 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 4.21 3654.4 - 520731 - - - -0.5055 - 1.835 0.484 - 210.2 1 2 0 -0.0005 9 0 0 0 7.36E+06 1.01E+07 - - - 4.3719 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19189.19189.2 0.0137 14-Jul K.GLLDVLPK.N "sp|O95071|UBR5_HUMAN,tr|E7ET84|E7ET84_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 853.5273 2.51 42454 19189 2 853.529007 427.7709 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.84 3654.6 - 384536 - - - 1.9952 - 1.493 0.343 - 141.2 1 2 0 0.0017 8 0 0 0 7.63E+06 3.04E+06 - - - 2.7826 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.19190.19190.2 0.0118 14-Jun K.GLLDVLPK[136.11].N "sp|O95071|UBR5_HUMAN,tr|E7ET84|E7ET84_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 861.5415 2.49 42455 19190 2 861.542871 431.778 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.84 3654.7 - 224908 - - - 1.5867 - 1.21 0.327 - 98.3 1 2 0 0.0014 8 0 0 0 7.52E+06 3.02E+06 - - - 2.0307 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19191.19191.2 0.0031 12-Jun K.FGFIGFK[136.11].S sp|Q9Y4C8|RBM19_HUMAN 1 822.452 0.99 42456 19191 2 822.45313 412.2333 Probable RNA-binding protein 19 OS=Homo sapiens OX=9606 GN=RBM19 PE=1 SV=3 8.75 3654.8 - 208536 - - - 1.4214 - 1.363 0.428 - 93.4 1 2 0 0.0012 7 0 0 0 2.88E+06 2.91E+06 - - - 3.1831 0.9947 230117_WJC_METTL3_WT_vs_EV_F05.19192.19192.2 0.556 18-Jul R.IIGYGLPFPK.N sp|Q9UDY4|DNJB4_HUMAN 1 1103.6379 6.64 42457 19192 2 1103.640834 552.8262 DnaJ homolog subfamily B member 4 OS=Homo sapiens OX=9606 GN=DNAJB4 PE=1 SV=1 8.59 3654.9 - 234228 - - - 2.6422 - 1.393 0.173 - 74.8 1 2 0 0.0029 10 0 0 0 4.14E+06 6.23E+05 - - - 1.2431 0.9909 230117_WJC_METTL3_WT_vs_EV_F05.19196.19196.2 0.00318 18-Aug R.FFLSSGLIDK[136.11].V sp|Q9BTV4|TMM43_HUMAN 1 1133.6212 0.79 42459 19196 2 1133.628594 567.8179 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 5.84 3655.5 - 3.47E+06 - - - 6.5128 - 1.615 0.396 - 141.5 1 2 0 0.0074 10 0 0 0 8.06E+06 1.02E+07 - - - 3.3015 0.9921 230117_WJC_METTL3_WT_vs_EV_F05.19198.19198.2 0.0158 16-Aug K.ISVNDFIIK.A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1047.5964 0.7 42461 19198 2 1047.600909 524.8055 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 3655.6 - 2.97E+06 - - - 4.2593 - 1.416 0.233 - 104.2 1 2 0 0.0045 9 0 0 0 7.72E+06 1.10E+07 - - - 1.7668 1 230117_WJC_METTL3_WT_vs_EV_F05.19199.19199.2 2.93E-05 13/24 V.ALVMLQEDELLSK.M sp|Q96A49|SYAP1_HUMAN 1 1487.7905 1.23 42462 19199 2 1487.795437 744.9025 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3655.7 - 2.76E+06 - - - 3.2968 - 2.86 0.494 - 604.3 1 1 0 0.0049 13 0 0 0 8.26E+06 6.73E+06 - - - 5.3851 1 230117_WJC_METTL3_WT_vs_EV_F05.19200.19200.2 9.99E-08 14/24 V.ALVMLQEDELLSK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1495.8047 1.44 42463 19200 2 1495.809605 748.9096 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3655.8 - 2.06E+06 - - - 3.2578 - 2.875 0.395 - 643.6 1 1 0 0.0049 13 0 0 0 1.68E+07 1.17E+07 - - - 4.6673 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.19201.19201.2 0.109 12-Jul R.LWAELLR.T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN" 3 899.5229 1.52 42464 19201 2 899.524946 450.7687 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 6 3656 - 1.66E+06 - - - 2.2879 - 1.473 0.185 - 192.2 1 2 0 0.0021 7 0 0 0 4.42E+06 2.91E+06 - - - 1.6339 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.19202.19202.2 0.0386 14-Jul K.LFVGFLNR.A "sp|Q9NXE4|NSMA3_HUMAN,tr|H7C0W5|H7C0W5_HUMAN,tr|H7C2E2|H7C2E2_HUMAN,tr|H7C2J2|H7C2J2_HUMAN,tr|H7C1Q6|H7C1Q6_HUMAN,tr|H7C235|H7C235_HUMAN,tr|A0A7P0TB44|A0A7P0TB44_HUMAN,tr|A0A7P0T9J6|A0A7P0T9J6_HUMAN,tr|A0A7P0TB24|A0A7P0TB24_HUMAN" 9 964.5494 2.1 42465 19202 2 964.553779 483.282 Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3 9.75 3656.1 - 1.57E+06 - - - 4.5016 - 1.529 0.346 - 173.7 1 2 0 0.0043 8 0 0 0 4.87E+06 2.32E+06 - - - 2.8758 0.9572 230117_WJC_METTL3_WT_vs_EV_F05.19203.19203.2 2.41 12-Jun R.LWAELLR[166.11].T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN" 3 909.5312 1.42 42466 19203 2 909.535638 455.7729 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 6 3656.2 - 1.34E+06 - - - 4.9256 - 1.373 0.097 - 114.6 1 2 0 0.0045 7 0 0 0 4.14E+06 2.91E+06 - - - 0.7605 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.19204.19204.2 0.000214 18-Aug R.SIPMTVDFIR[166.11].L sp|P00492|HPRT_HUMAN 1 1187.6248 1.96 42467 19204 2 1187.629575 594.8197 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 5.55 3656.3 - 1.28E+06 - - - 4.0206 - 1.816 0.408 - 227.4 1 2 0 0.0048 10 0 0 0 1.36E+07 6.94E+06 - - - 3.7184 0.8531 230117_WJC_METTL3_WT_vs_EV_F05.19206.19206.2 0.104 20-Oct R.FLQSAKNIAER[166.11].V sp|Q9UJV3|TRIM1_HUMAN 1 1285.7018 - 42469 19206 2 1285.704071 643.8582 Probable E3 ubiquitin-protein ligase MID2 OS=Homo sapiens OX=9606 GN=MID2 PE=1 SV=3 8.75 3656.6 - 1.00E+06 - - - 1.7625 - 2.105 0.213 - 321.8 1 2 1 0.0023 11 0 0 0 - - - - - 2.6271 0.976 230117_WJC_METTL3_WT_vs_EV_F05.19209.19209.2 0.207 14-Jun K.FITIFGTR.S "sp|P08758|ANXA5_HUMAN,tr|D6RBL5|D6RBL5_HUMAN,tr|D6RBE9|D6RBE9_HUMAN" 3 953.5335 0.78 42472 19209 2 953.5376 477.774 Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5 PE=1 SV=2 9.75 3657 - 586429 - - - 4.3501 - 1.101 0.214 - 71.9 1 2 0 0.0041 8 0 0 0 4.19E+06 5.37E+06 - - - 0.9105 1 230117_WJC_METTL3_WT_vs_EV_F05.19211.19211.2 3.62E-05 13/26 R.WSSLAC[160.03]NIALDAVK.M "sp|P49368|TCPG_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1546.7814 -1 42474 19211 2 1546.789757 774.398 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.83 3657.2 - 392752 - - - 5.4261 - 2.443 0.563 - 501.7 1 2 0 0.0084 14 0 0 0 0.00E+00 0.00E+00 - - - 5.4382 1 230117_WJC_METTL3_WT_vs_EV_F05.19213.19213.2 5.89E-06 20-Oct R.FFDEESYSLLR.K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1404.6561 1.64 42476 19213 2 1404.657994 703.3353 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3657.5 - 293730 - - - 1.3156 - 2.457 0.624 - 216.4 1 2 0 0.0018 11 0 0 0 1.01E+08 6.19E+07 - - - 6.0811 1 230117_WJC_METTL3_WT_vs_EV_F05.19221.19221.2 0.000164 14/22 K.ATGILLYGLASR.L "sp|P47897|SYQ_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|F2Z2V6|F2Z2V6_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 9 1233.7081 1.69 42483 19221 2 1233.71441 617.8613 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 8.79 3658.4 - 1.01E+06 - - - 5.0968 - 2.489 0.43 - 759.1 1 2 0 0.0063 12 0 0 0 1.39E+07 8.25E+06 - - - 4.6143 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.19222.19222.2 0.00165 18-Oct K.TFTLSATLLR[166.11].H sp|Q9UEG4|ZN629_HUMAN 1 1131.6527 0.44 42484 19222 2 1131.652775 566.8336 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.41 3658.5 - 773842 - - - 0.0406 - 1.771 0.379 - 255.4 1 2 0 0 10 0 0 0 4.55E+06 1.04E+07 - - - 3.4356 0.9959 230117_WJC_METTL3_WT_vs_EV_F05.19223.19223.2 0.507 16-Oct K.GVILLIVDK.A "sp|P78344|IF4G2_HUMAN,tr|H0YE44|H0YE44_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 8 968.627 1.54 42485 19223 2 968.630068 485.3208 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.84 3658.6 - 717207 - - - 3.1488 - 1.923 0.103 - 276.1 1 2 0 0.0031 9 0 0 0 3.18E+06 2.07E+06 - - - 1.6925 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.19224.19224.2 0.000373 16-Aug R.LSYPTFFPR.F "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1126.5811 1.98 42486 19224 2 1126.57817 564.2978 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 8.75 3658.7 - 699236 - - - -2.6283 - 1.462 0.412 - 177.3 1 2 0 -0.003 9 0 0 0 1.75E+07 8.83E+06 - - - 3.1819 1 230117_WJC_METTL3_WT_vs_EV_F05.19225.19225.3 0.000153 18/56 K.LLQVASPFLEPHLVR.M "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1717.9879 3.22 42487 19225 3 1717.993182 573.6699 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 6.75 3658.9 - 670914 - - - 3.0594 - 3.63 0.523 - 443.1 1 2 0 0.0053 15 0 0 0 5.40E+06 1.68E+06 - - - 7.7336 0.9319 230117_WJC_METTL3_WT_vs_EV_F05.19228.19228.2 2.63 14-Jun R.ILPWSTFR[166.11].L "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1028.5683 0.6 42490 19228 2 1028.571401 515.2914 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3659.2 - 487282 - - - 3.0421 - 1.119 0.029 - 105.3 1 2 0 0.0031 8 0 0 0 6.20E+06 1.03E+07 - - - -0.4067 1 230117_WJC_METTL3_WT_vs_EV_F05.19229.19229.2 0.0498 13/20 R.FFDEESYSLLR[166.11].K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1414.6644 1.64 42491 19229 2 1414.669503 708.3395 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3659.3 - 470202 - - - 3.5959 - 2.617 0.515 - 411.3 1 2 0 0.0051 11 0 0 0 1.02E+08 6.20E+07 - - - 5.4457 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.19230.19230.2 4.19 16-Aug K.GVILLIVDK[136.11].A "sp|P78344|IF4G2_HUMAN,tr|H0YE44|H0YE44_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 8 976.6412 1.54 42492 19230 2 976.644815 489.3279 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.84 3659.4 - 443090 - - - 3.683 - 1.697 0.216 - 160.2 1 2 0 0.0036 9 0 0 0 3.18E+06 2.07E+06 - - - 2.1653 1 230117_WJC_METTL3_WT_vs_EV_F05.19232.19232.2 0.00445 26-Dec K.VLELDPALAPVVSR.E "sp|O00170|AIP_HUMAN,tr|A0A804HKK3|A0A804HKK3_HUMAN,tr|A0A804HKL7|A0A804HKL7_HUMAN,tr|A0A804HJ46|A0A804HJ46_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN" 6 1477.8504 5.8 42494 19232 2 1477.854385 739.9325 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 4.37 3659.7 - 240147 - - - 2.6762 - 2.584 0.468 - 286.9 1 2 0 0.004 14 0 0 0 2.06E+07 3.56E+06 - - - 4.8787 1 230117_WJC_METTL3_WT_vs_EV_F05.19233.19233.2 1.71E-05 13/22 R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.15 42495 19233 2 1323.804102 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3659.8 - 176146 - - - 2.6658 - 2.362 0.545 - 447.6 1 2 0 0.0035 12 0 0 0 2.43E+09 2.12E+09 - - - 5.3268 0.9214 230117_WJC_METTL3_WT_vs_EV_F05.19239.19239.2 20.7 22-Apr R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.15 42500 19239 2 1315.788696 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3660.5 - 1.68E+06 - - - 1.7655 - 0.776 0.103 - 44.9 1 2 0 0.0023 12 0 0 0 2.43E+09 2.12E+09 - - - -0.8662 1 230117_WJC_METTL3_WT_vs_EV_F05.19242.19242.2 1.45E-07 14/24 R.IPSPLGYAAIPIK[136.11].F sp|Q9Y3A4|RRP7A_HUMAN 1 1346.8053 1.48 42503 19242 2 1346.807702 674.4099 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 8.59 3660.8 - 573542 - - - 1.7657 - 2.441 0.543 - 505.4 1 2 0 0.0024 13 0 0 0 4.91E+07 3.33E+07 - - - 5.3412 1 230117_WJC_METTL3_WT_vs_EV_F05.19243.19243.2 2.79E-06 18-Sep K.TFTLSATLLR.H sp|Q9UEG4|ZN629_HUMAN 1 1121.6445 0.43 42504 19243 2 1121.64985 561.8295 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.41 3660.8 - 374391 - - - 4.8063 - 1.911 0.561 - 263.3 1 2 0 0.0054 10 0 0 0 4.55E+06 1.05E+07 - - - 4.9906 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.19247.19247.2 0.00323 20-Aug K.MALDIEIAAYR[166.11].K "sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,sp|P12036|NFH_HUMAN,sp|P07196|NFL_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 6 1274.6568 1.28 42508 19247 2 1274.656763 638.3357 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.37 3661.2 - 116670 - - - -0.0518 - 1.772 0.366 - 121 1 2 0 -0.0001 11 0 0 0 3.63E+06 2.84E+06 - - - 3.2919 0.976 230117_WJC_METTL3_WT_vs_EV_F05.19252.19252.2 0.00144 14-Oct R.WALGQVFR[166.11].Q "sp|P26572|MGAT1_HUMAN,tr|D6RF69|D6RF69_HUMAN" 2 985.5373 1.25 42511 19252 2 985.544634 493.7759 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 9.75 3661.8 - 1.06E+06 - - - 7.4355 - 1.894 0.237 - 471 1 2 0 0.0073 8 0 0 0 1.44E+07 1.15E+07 - - - 2.7154 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19254.19254.2 0.000109 16-Nov R.VLEALLPLK.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 994.6427 1.63 42513 19254 2 994.645374 498.3286 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3662 - 1.07E+06 - - - 2.7196 - 1.982 0.297 - 381.8 1 2 0 0.0027 9 0 0 0 1.13E+08 6.92E+07 - - - 3.2129 1 230117_WJC_METTL3_WT_vs_EV_F05.19255.19255.2 0.00121 18-Dec R.LGLDDFESLK[136.11].V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1143.5903 0.4 42514 19255 2 1143.595815 572.8024 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3662.1 - 695576 - - - 4.8182 - 2.258 0.479 - 315.2 1 2 0 0.0055 10 0 0 0 4.72E+07 1.18E+08 - - - 4.8506 1 230117_WJC_METTL3_WT_vs_EV_F05.19257.19257.2 0.000169 24-Nov R.IITLTGPTNAIFK[136.11].A sp|Q15365|PCBP1_HUMAN 1 1395.8217 3.48 42516 19257 2 1395.825589 698.9181 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3662.4 - 606014 - - - 2.7847 - 2.274 0.466 - 327.9 1 2 0 0.0039 13 0 0 0 2.33E+08 6.69E+07 - - - 4.5902 0.9568 230117_WJC_METTL3_WT_vs_EV_F05.19258.19258.2 0.946 14-Jul R.ILPWSTFR.L "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1018.56 1.48 42517 19258 2 1018.564993 510.2873 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3662.5 - 444308 - - - 4.9001 - 1.134 0.179 - 147.6 1 2 0 0.005 8 0 0 0 5.72E+06 3.86E+06 - - - 0.7408 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.19259.19259.2 0.00297 18-Sep R.VIEQLLVGLK.D "sp|Q9BTW9|TBCD_HUMAN,tr|A0A804HJ32|A0A804HJ32_HUMAN,tr|A0A804HKT8|A0A804HKT8_HUMAN,tr|A0A804HHW7|A0A804HHW7_HUMAN,tr|A0A804HL21|A0A804HL21_HUMAN,tr|A0A804HKB9|A0A804HKB9_HUMAN,tr|A0A804HJY5|A0A804HJY5_HUMAN,tr|A0A804HI02|A0A804HI02_HUMAN,tr|A0A804HIU1|A0A804HIU1_HUMAN,tr|A0A804HJ57|A0A804HJ57_HUMAN,tr|A0A804HLF8|A0A804HLF8_HUMAN,tr|A0A804HL62|A0A804HL62_HUMAN,tr|A0A804HIC0|A0A804HIC0_HUMAN,tr|J3KR97|J3KR97_HUMAN,tr|A0A804HI57|A0A804HI57_HUMAN,tr|A0A804HIN6|A0A804HIN6_HUMAN,tr|A0A804HLI2|A0A804HLI2_HUMAN" 17 1110.7012 1.29 42518 19259 2 1110.705435 556.3579 Tubulin-specific chaperone D OS=Homo sapiens OX=9606 GN=TBCD PE=1 SV=2 5.97 3662.6 - 349173 - - - 3.7715 - 1.907 0.362 - 147.8 1 2 0 0.0042 10 0 0 0 5.63E+06 4.37E+06 - - - 3.5153 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.19268.19268.3 4.35E-06 Dec-44 R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 0.54 42527 19268 3 1315.790965 439.6027 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3663.8 - 99903.3 - - - 3.4899 - 2.204 0.508 - 171.3 1 2 0 0.0046 12 0 0 0 1.99E+07 3.67E+07 - - - 6.3929 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19273.19273.2 0.16 16-Aug R.VLEALLPLK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1002.6569 1.63 42530 19273 2 1002.658215 502.3357 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3664.4 - 1.42E+07 - - - 1.3424 - 1.916 0.378 - 233 1 2 0 0.0013 9 0 0 0 1.13E+08 6.92E+07 - - - 3.7137 1 230117_WJC_METTL3_WT_vs_EV_F05.19274.19274.2 0.0018 18-Sep R.LGLDDFESLK.V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1135.5761 0.4 42531 19274 2 1135.579389 568.7953 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3664.4 - 7.63E+06 - - - 2.8919 - 2.073 0.492 - 150.2 1 2 0 0.0033 10 0 0 0 4.72E+07 1.18E+08 - - - 4.7087 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19275.19275.2 0.00291 16-Nov K.TLEEILLER.A "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 3 1114.6234 1.8 42532 19275 2 1114.624306 558.319 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.25 3664.5 - 5.72E+06 - - - 0.8218 - 2.233 0.376 - 362.7 1 2 0 0.0009 9 0 0 0 6.43E+07 3.57E+07 - - - 4.142 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19276.19276.2 0.136 24-Oct K.LGLSLVVPGGGIK.K sp|Q99747|SNAG_HUMAN 1 1208.7493 2.97 42533 19276 2 1208.751528 605.3819 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3664.6 - 4.32E+06 - - - 1.8771 - 2.381 0.302 - 244.2 1 2 0 0.0023 13 0 0 0 1.34E+07 4.51E+06 - - - 3.4974 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.19277.19277.3 0.000536 Dec-44 R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 0.97 42534 19277 3 1323.801366 442.2741 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3664.7 - 3.17E+06 - - - 0.599 - 2.116 0.459 - 191.4 1 2 0 0.0008 12 0 0 0 1.93E+07 1.99E+07 - - - 5.7348 0.9864 230117_WJC_METTL3_WT_vs_EV_F05.19279.19279.2 0.031 18-Sep K.VPSLVGSFIR[166.11].S "sp|P78417|GSTO1_HUMAN,tr|Q5TA02|Q5TA02_HUMAN" 2 1083.6316 1.21 42536 19279 2 1083.637818 542.8231 Glutathione S-transferase omega-1 OS=Homo sapiens OX=9606 GN=GSTO1 PE=1 SV=2 9.72 3664.9 - 2.02E+06 - - - 5.7381 - 1.604 0.25 - 155.1 1 2 0 0.0062 10 0 0 0 7.09E+06 5.87E+06 - - - 2.2044 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.19281.19281.2 0.333 24-Sep K.LGLSLVVPGGGIK[136.11].K sp|Q99747|SNAG_HUMAN 1 1216.7635 2.97 42538 19281 2 1216.765362 609.389 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3665.1 - 1.67E+06 - - - 1.564 - 1.702 0.318 - 149.4 1 2 0 0.0019 13 0 0 0 1.34E+07 4.51E+06 - - - 2.754 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.19282.19282.2 0.000856 18-Jul K.LLPFLAPGAR.A "sp|Q9BTY7|HGH1_HUMAN,tr|E9PIX0|E9PIX0_HUMAN" 2 1053.6335 23.61 42539 19282 2 1053.636818 527.824 Protein HGH1 homolog OS=Homo sapiens OX=9606 GN=HGH1 PE=1 SV=1 9.75 3665.2 - 1.59E+06 - - - 3.1482 - 1.789 0.303 - 101 2 2 0 0.0033 10 0 0 0 5.66E+06 2.40E+05 - - - 2.767 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.19285.19285.2 0.027 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 12.66 42542 19285 2 1006.573313 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3665.6 - 2.79E+06 - - - 3.3927 - 1.614 0.434 - 217.2 1 2 0 0.0034 9 0 0 0 6.63E+06 5.24E+05 - - - 3.6304 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.19287.19287.2 1.33 12-Jul K.LFGELFK[136.11].L "sp|Q15032|R3HD1_HUMAN,tr|A0A804HIA8|A0A804HIA8_HUMAN,tr|H7C207|H7C207_HUMAN" 3 860.4887 1.14 42544 19287 2 860.489282 431.2516 R3H domain-containing protein 1 OS=Homo sapiens OX=9606 GN=R3HDM1 PE=1 SV=3 6 3665.8 - 1.21E+06 - - - 0.6287 - 1.46 0.148 - 117.7 1 2 0 0.0005 7 0 0 0 5.27E+06 4.63E+06 - - - 1.3331 0.9709 230117_WJC_METTL3_WT_vs_EV_F05.19290.19290.2 3.46 16-Jun K.VVINVPIFK.D "sp|P48506|GSH1_HUMAN,tr|B4E2I4|B4E2I4_HUMAN,tr|A0A2R8YEL6|A0A2R8YEL6_HUMAN,tr|A0A0C4DGB2|A0A0C4DGB2_HUMAN,tr|E1CEI4|E1CEI4_HUMAN" 5 1027.643 2.16 42547 19290 2 1027.645503 514.8288 Glutamate--cysteine ligase catalytic subunit OS=Homo sapiens OX=9606 GN=GCLC PE=1 SV=2 8.72 3666.2 - 937679 - - - 2.4328 - 1.09 0.088 - 73.9 1 2 0 0.0025 9 0 0 0 2.37E+06 1.10E+06 - - - -0.0605 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19292.19292.3 0.00882 Dec-40 R.FIMILTEHLVR[166.11].C "sp|Q09161|NCBP1_HUMAN,tr|X6R941|X6R941_HUMAN" 2 1380.7827 0.93 42549 19292 3 1380.783871 461.2682 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 6.75 3666.5 - 904305 - - - 0.8495 - 1.926 0.316 - 164.5 1 2 0 0.0012 11 0 0 0 4.65E+06 4.99E+06 - - - 3.9248 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.19295.19295.2 0.00192 22-Oct R.NIPGITLLNVSK[136.11].L "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1275.7642 0.87 42551 19295 2 1275.768513 638.8894 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.75 3667 - 133368 - - - 3.3909 - 1.848 0.284 - 219 1 2 0 0.0043 12 0 0 0 2.85E+06 3.28E+06 - - - 2.7531 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.19297.19297.2 0.00228 14-Jul K.LVYVDLLR.E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 989.591 1.87 42553 19297 2 989.592082 495.8028 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.84 3667.1 - 1.79E+06 - - - 1.1267 - 1.527 0.364 - 194.5 1 2 0 0.0011 8 0 0 0 3.61E+07 1.93E+07 - - - 3.0058 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19300.19300.2 0.00663 16-Sep K.LPFPIIDDR.N sp|P30041|PRDX6_HUMAN 1 1084.5917 1.32 42556 19300 2 1084.590608 543.3031 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.21 3667.3 - 676409 - - - -1.0031 - 1.949 0.418 - 368.4 1 2 0 -0.0011 9 0 0 0 1.11E+08 8.41E+07 - - - 4.0586 0.9347 230117_WJC_METTL3_WT_vs_EV_F05.19302.19302.2 4.76 12-May K.LFGELFK.L "sp|Q15032|R3HD1_HUMAN,tr|A0A804HIA8|A0A804HIA8_HUMAN,tr|H7C207|H7C207_HUMAN" 3 852.4745 1.14 42558 19302 2 852.47409 427.2445 R3H domain-containing protein 1 OS=Homo sapiens OX=9606 GN=R3HDM1 PE=1 SV=3 6 3667.6 - 311992 - - - -0.529 - 1.157 0.04 - 63.4 2 2 0 -0.0005 7 0 0 0 5.27E+06 4.63E+06 - - - -0.3361 1 230117_WJC_METTL3_WT_vs_EV_F05.19307.19307.2 9.30E-05 16-Oct K.LPFPIIDDR[166.11].N sp|P30041|PRDX6_HUMAN 1 1094.6 1.32 42561 19307 2 1094.600019 548.3073 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.21 3668.1 - 1.54E+06 - - - 0.0484 - 2.14 0.525 - 512.5 1 2 0 0.0001 9 0 0 0 1.11E+08 8.41E+07 - - - 5.1197 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.19308.19308.2 0.0136 12-Aug R.SGMFWLR[166.11].F sp|P31930|QCR1_HUMAN 1 905.4457 1.12 42562 19308 2 905.445636 453.7301 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 9.47 3668.2 - 437790 - - - -0.0861 - 1.592 0.348 - 300.6 1 2 0 -0.0001 7 0 0 0 6.42E+06 5.74E+06 - - - 3.0847 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19309.19309.2 0.00816 20-Oct R.LLGLGVTDFSR[166.11].A "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 1186.6585 0.69 42563 19309 2 1186.658086 594.3365 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 5.84 3668.4 - 698275 - - - -0.3851 - 2.321 0.408 - 281.1 1 2 0 -0.0005 11 0 0 0 7.48E+06 1.09E+07 - - - 4.3321 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19313.19313.2 0.00438 12-Aug R.SGMFWLR.F sp|P31930|QCR1_HUMAN 1 895.4374 1.11 42565 19313 2 895.438379 448.726 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 9.47 3668.9 - 932714 - - - 1.0442 - 1.715 0.389 - 300.3 1 2 0 0.0009 7 0 0 0 6.44E+06 5.79E+06 - - - 3.623 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19314.19314.2 0.000743 20-Nov R.LLGLGVTDFSR.A "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 1176.6503 0.69 42566 19314 2 1176.649751 589.3324 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 5.84 3669 - 1.04E+06 - - - -0.4436 - 2.426 0.39 - 333.1 1 2 0 -0.0005 11 0 0 0 7.48E+06 1.09E+07 - - - 4.3189 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.19317.19317.2 2.74 12-Jul M.GLLSILR.K "sp|P36405|ARL3_HUMAN,sp|Q14517|FAT1_HUMAN,tr|A0A087WVP1|A0A087WVP1_HUMAN" 3 770.5014 1.41 42569 19317 2 770.500801 386.258 ADP-ribosylation factor-like protein 3 OS=Homo sapiens OX=9606 GN=ARL3 PE=1 SV=2 9.75 3669.4 - 829353 - - - -0.8086 - 1.422 0.218 - 190.4 1 2 0 -0.0006 7 0 0 0 4.70E+06 3.32E+06 - - - 1.7665 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19320.19320.2 0.344 22-Nov K.LILSLEGGYNLR[166.11].A "sp|Q9UBN7|HDAC6_HUMAN,tr|A0A2R8YCS4|A0A2R8YCS4_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 3 1356.7641 0.23 42572 19320 2 1356.76408 679.3893 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 6 3669.8 - 559179 - - - 0.0066 - 2.05 0.303 - 363.3 1 2 0 0 12 0 0 0 4.92E+05 2.16E+06 - - - 3.1677 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19321.19321.2 0.00331 22-Nov R.GILLFGPPGTGK.S "sp|Q9UN37|VPS4A_HUMAN,sp|O75351|VPS4B_HUMAN,sp|Q6PIW4|FIGL1_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 4 1155.6652 5.9 42573 19321 2 1155.665882 578.8399 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 8.75 3669.9 - 554580 - - - 0.5945 - 2.203 0.38 - 303.4 1 2 0 0.0007 12 0 0 0 7.10E+06 1.20E+06 - - - 3.9256 0.9851 230117_WJC_METTL3_WT_vs_EV_F05.19322.19322.2 0.206 14-Jun K.GVLSDLTK.V "sp|Q8NG11|TSN14_HUMAN,tr|A6NEP9|A6NEP9_HUMAN,tr|H7BXY6|H7BXY6_HUMAN" 3 831.4702 5.01 42574 19322 2 831.469709 416.7424 Tetraspanin-14 OS=Homo sapiens OX=9606 GN=TSPAN14 PE=1 SV=1 5.84 3670.1 - 554028 - - - -0.5701 - 1.389 0.09 - 117.6 1 2 0 -0.0005 8 0 0 0 8.93E+06 1.78E+06 - - - 0.6966 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.19324.19324.2 0.0201 18-Sep K.LFLELEPQVR[166.11].D "sp|Q13098|CSN1_HUMAN,tr|A0A096LP07|A0A096LP07_HUMAN,tr|A8K070|A8K070_HUMAN,tr|C9JFE4|C9JFE4_HUMAN,tr|A0A096LPJ3|A0A096LPJ3_HUMAN" 5 1252.7055 1.67 42576 19324 2 1252.701712 627.36 COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4 4.53 3670.3 - 491453 - - - -3.0183 - 1.9 0.351 - 307.5 1 2 0 -0.0038 10 0 0 0 9.33E+06 5.59E+06 - - - 3.4239 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.19326.19326.2 0.00226 22-Sep R.NIPGITLLNVSK.L "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1267.75 0.87 42578 19326 2 1267.74922 634.8823 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.75 3670.6 - 350491 - - - -0.605 - 1.629 0.32 - 185.6 1 2 0 -0.0008 12 0 0 0 2.85E+06 3.28E+06 - - - 2.6882 1 230117_WJC_METTL3_WT_vs_EV_F05.19333.19333.2 3.04E-07 15/24 R.TPFTTAQLLALER.K sp|P28360|MSX1_HUMAN 1 1459.8035 1.63 42584 19333 2 1459.80416 730.909 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3671.3 - 2.67E+06 - - - 0.4665 - 2.94 0.58 - 788.7 1 2 0 0.0007 13 0 0 0 1.28E+07 7.84E+06 - - - 6.0924 1 230117_WJC_METTL3_WT_vs_EV_F05.19334.19334.2 1.97E-05 13/24 R.TPFTTAQLLALER[166.11].K sp|P28360|MSX1_HUMAN 1 1469.8117 1.63 42585 19334 2 1469.811151 735.9132 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3671.4 - 1.27E+06 - - - -0.4069 - 2.575 0.519 - 414.8 1 2 0 -0.0006 13 0 0 0 1.28E+07 7.84E+06 - - - 5.3017 0.996 230117_WJC_METTL3_WT_vs_EV_F05.19335.19335.2 0.042 18-Oct R.LTC[160.03]LGVWLDK[136.11].V sp|Q9NWT1|PK1IP_HUMAN 1 1211.6464 0.87 42586 19335 2 1211.644482 606.8305 p21-activated protein kinase-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAK1IP1 PE=1 SV=2 5.83 3671.5 - 987092 - - - -1.5673 - 1.852 0.217 - 285.1 1 2 0 -0.0019 10 0 0 0 3.58E+06 4.11E+06 - - - 2.3634 0.9948 230117_WJC_METTL3_WT_vs_EV_F05.19336.19336.2 0.82 24-Aug K.AALEAVGGTVVLE.- sp|P52815|RM12_HUMAN 1 1227.6711 - 42587 19336 2 1227.670922 614.8428 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 4.24 3671.6 - 729995 - - - -0.1189 - 1.398 0.188 - 105.9 1 2 0 -0.0001 13 0 0 0 - - - - - 1.2894 0.998 230117_WJC_METTL3_WT_vs_EV_F05.19338.19338.2 0.043 18-Jul R.LLLQIPSTIR[166.11].S sp|Q16394|EXT1_HUMAN 1 1162.7313 1.3 42589 19338 2 1162.731087 582.3729 Exostosin-1 OS=Homo sapiens OX=9606 GN=EXT1 PE=1 SV=2 9.75 3671.9 - 419172 - - - -0.1952 - 1.622 0.24 - 142.8 1 2 0 -0.0002 10 0 0 0 3.64E+06 2.81E+06 - - - 2.1636 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19344.19344.2 0.00367 16-Nov K.IPSVLFLGK.L sp|Q8IW75|SPA12_HUMAN 1 972.6008 232.37 42593 19344 2 972.604437 487.3077 Serpin A12 OS=Homo sapiens OX=9606 GN=SERPINA12 PE=1 SV=1 8.75 3672.6 - 639496 - - - 3.7353 - 2.1 0.432 - 320.6 1 2 0 0.0036 9 0 0 0 7.51E+06 3.23E+04 - - - 4.3771 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.19345.19345.2 0.00723 18-Oct K.SLLFVNTLER.S "sp|Q9NY93|DDX56_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1190.6659 0.55 42594 19345 2 1190.671375 596.3402 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 5.72 3672.7 - 564955 - - - 4.579 - 2.143 0.323 - 381.5 1 2 0 0.0055 10 0 0 0 9.31E+06 1.68E+07 - - - 3.5525 0.9952 230117_WJC_METTL3_WT_vs_EV_F05.19349.19349.2 0.702 12-Jul K.FDLIWNR.A "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|H0YEW4|H0YEW4_HUMAN,tr|A8MRA7|A8MRA7_HUMAN,tr|H0YD21|H0YD21_HUMAN" 5 962.4974 2.77 42598 19349 2 962.499774 482.256 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 5.84 3673.2 - 138693 - - - 2.4655 - 1.689 0.072 - 167.3 1 2 0 0.0024 7 0 0 0 5.52E+06 1.99E+06 - - - 1.2328 1 230117_WJC_METTL3_WT_vs_EV_F05.19352.19352.2 6.35E-06 14/22 K.YDAFLASESLIK[136.11].Q sp|P62906|RL10A_HUMAN 1 1363.7115 0.9 42600 19352 2 1363.71508 682.863 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.37 3673.6 - 1.59E+06 - - - 2.6377 - 2.683 0.577 - 645.3 1 2 0 0.0036 12 0 0 0 6.11E+07 6.78E+07 - - - 5.8984 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.19354.19354.2 0.000123 16-Sep K.DVDLEFLAK[136.11].M "sp|P55072|TERA_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN" 6 1056.5583 0.74 42601 19354 2 1056.561938 529.2864 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.03 3673.8 - 1.81E+06 - - - 3.465 - 1.68 0.34 - 214.3 1 2 0 0.0037 9 0 0 0 9.55E+06 1.29E+07 - - - 3.052 0.9907 230117_WJC_METTL3_WT_vs_EV_F05.19355.19355.2 5.77 14-Jun R.LPLFGLGR[166.11].L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 881.5362 1.32 42602 19355 2 881.538372 441.7754 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3673.9 - 1.07E+06 - - - 2.4151 - 1.303 0.119 - 173.9 1 2 0 0.0021 8 0 0 0 1.91E+08 1.45E+08 - - - 0.7175 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19357.19357.2 0.0132 18-Sep K.SLLFVNTLER[166.11].S "sp|Q9NY93|DDX56_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1200.6742 0.49 42604 19357 2 1200.675781 601.3444 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 5.72 3673.9 - 1.21E+06 - - - 1.3226 - 2.084 0.324 - 296 1 2 0 0.0016 10 0 0 0 9.46E+06 1.94E+07 - - - 3.4832 0.997 230117_WJC_METTL3_WT_vs_EV_F05.19358.19358.2 0.504 14-Sep R.LPLFGLGR.L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 871.528 1.32 42605 19358 2 871.52879 436.7713 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3674 - 1.21E+06 - - - 0.9374 - 1.568 0.138 - 365.8 1 2 0 0.0008 8 0 0 0 1.91E+08 1.45E+08 - - - 1.4166 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19359.19359.2 8.40E-06 13/24 R.ILDIDNVDLAMGK[136.11].M sp|O43615|TIM44_HUMAN 1 1423.7472 2.71 42606 19359 2 1423.750404 712.8809 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3674.1 - 938272 - - - 2.2385 - 2.374 0.405 - 542 1 2 0 0.0032 13 0 0 0 2.33E+07 8.60E+06 - - - 4.2503 1 230117_WJC_METTL3_WT_vs_EV_F05.19360.19360.2 1.34E-05 20-Sep K.VGEVTYVELFK.D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1282.6809 1.88 42607 19360 2 1282.68566 642.3477 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.53 3674.2 - 847496 - - - 3.7071 - 2.283 0.457 - 280.4 1 2 0 0.0048 11 0 0 0 9.08E+07 4.82E+07 - - - 4.6481 0.9944 230117_WJC_METTL3_WT_vs_EV_F05.19363.19363.2 0.898 18-May R.LLLQIPSTIR.S sp|Q16394|EXT1_HUMAN 1 1152.723 1.3 42610 19363 2 1152.726149 577.3688 Exostosin-1 OS=Homo sapiens OX=9606 GN=EXT1 PE=1 SV=2 9.75 3674.5 - 589913 - - - 2.6936 - 1.371 0.217 - 68.8 5 2 0 0.0031 10 0 0 0 3.64E+06 2.81E+06 - - - 1.2113 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.19365.19365.2 0.0425 16-Sep R.VVVLGLLPR.G "sp|Q15102|PA1B3_HUMAN,tr|M0R389|M0R389_HUMAN" 2 964.6433 1.49 42612 19365 2 964.644515 483.3289 Platelet-activating factor acetylhydrolase IB subunit alpha1 OS=Homo sapiens OX=9606 GN=PAFAH1B3 PE=1 SV=1 9.72 3674.7 - 300103 - - - 1.2212 - 1.679 0.259 - 229.7 1 2 0 0.0012 9 0 0 0 4.15E+06 2.78E+06 - - - 2.4528 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.19367.19367.2 9.87E-05 28-Aug R.VLVVGAGGIGC[160.03]ELLK[136.11].N "sp|Q9UBT2|SAE2_HUMAN,tr|U3KQ55|U3KQ55_HUMAN,tr|K7EPL2|K7EPL2_HUMAN,tr|K7ES38|K7ES38_HUMAN" 4 1491.8574 1.64 42614 19367 2 1491.861952 746.936 SUMO-activating enzyme subunit 2 OS=Homo sapiens OX=9606 GN=UBA2 PE=1 SV=2 5.97 3674.9 - 254182 - - - 3.0271 - 1.798 0.461 - 67.2 1 2 0 0.0045 15 0 0 0 1.32E+06 8.03E+05 - - - 3.8869 0.996 230117_WJC_METTL3_WT_vs_EV_F05.19370.19370.2 0.0255 18-Nov K.AIDLFTDAIK.L "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 1105.6019 0.7 42615 19370 2 1105.607837 553.8082 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 4.21 3675.4 - 4.10E+06 - - - 5.3464 - 1.675 0.394 - 329.3 1 2 0 0.0059 10 0 0 0 3.77E+07 5.39E+07 - - - 3.389 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.19371.19371.2 0.00143 20-Nov K.LWDLASGTLYK.E sp|O75529|TAF5L_HUMAN 1 1265.6656 1.26 42616 19371 2 1265.67279 633.8401 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 5.83 3675.6 - 1.04E+06 - - - 5.6895 - 1.961 0.435 - 402.1 1 2 0 0.0072 11 0 0 0 1.64E+07 1.31E+07 - - - 4.0735 1 230117_WJC_METTL3_WT_vs_EV_F05.19372.19372.2 7.19E-06 20-Dec K.LWDLASGTLYK[136.11].E sp|O75529|TAF5L_HUMAN 1 1273.6798 1.27 42617 19372 2 1273.685121 637.8472 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 5.83 3675.7 - 940853 - - - 4.1863 - 2.296 0.528 - 482.6 1 2 0 0.0053 11 0 0 0 1.65E+07 1.31E+07 - - - 5.1876 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.19373.19373.2 0.274 16-Dec K.WQALLVQIR[166.11].K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1135.6741 1.08 42618 19373 2 1135.677617 568.8443 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.75 3675.8 - 750657 - - - 3.0669 - 2.13 0.365 - 626.1 1 2 0 0.0035 9 0 0 0 1.45E+07 1.34E+07 - - - 3.9233 1 230117_WJC_METTL3_WT_vs_EV_F05.19374.19374.2 3.30E-06 20-Dec K.LGGNEIVSFLK.G "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 4 1175.655 4.05 42619 19374 2 1175.660694 588.8348 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6 3675.9 - 544918 - - - 4.8228 - 2.458 0.504 - 314.3 1 2 0 0.0057 11 0 0 0 3.37E+07 8.32E+06 - - - 5.1947 0.9867 230117_WJC_METTL3_WT_vs_EV_F05.19375.19375.2 0.0917 14-Jul R.LWLLDDSK.T "sp|O43639|NCK2_HUMAN,sp|P16333|NCK1_HUMAN,tr|E7EPF5|E7EPF5_HUMAN,tr|E7ERP6|E7ERP6_HUMAN,tr|C9J0K5|C9J0K5_HUMAN,tr|C9K098|C9K098_HUMAN,tr|C9J869|C9J869_HUMAN,tr|C9JVV5|C9JVV5_HUMAN,tr|E9PEE2|E9PEE2_HUMAN,tr|H7C5C7|H7C5C7_HUMAN" 10 988.5229 1.47 42620 19375 2 988.52761 495.2687 Cytoplasmic protein NCK2 OS=Homo sapiens OX=9606 GN=NCK2 PE=1 SV=2 4.21 3676.1 - 291792 - - - 4.7171 - 1.634 0.144 - 143.4 1 2 0 0.0047 8 0 0 0 3.89E+06 2.65E+06 - - - 1.584 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.19377.19377.2 0.000481 20-Dec K.ILEAVTLVQLK.E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1225.7646 0.81 42622 19377 2 1225.768684 613.8896 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6 3676.3 - 228947 - - - 3.3522 - 2.502 0.39 - 326.3 1 2 0 0.0041 11 0 0 0 6.00E+06 7.37E+06 - - - 4.4012 1 230117_WJC_METTL3_WT_vs_EV_F05.19379.19379.2 5.74E-07 13/26 R.WTTEEQLLAVQAIR.K sp|Q9UKL0|RCOR1_HUMAN 1 1656.8835 1.36 42624 19379 2 1656.888294 829.449 REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2 4.53 3676.6 - 146981 - - - 2.8807 - 2.909 0.569 - 575.3 1 2 0 0.0048 14 0 0 0 9.07E+05 6.68E+05 - - - 5.9217 1 230117_WJC_METTL3_WT_vs_EV_F05.19383.19383.2 6.46E-06 13/24 R.IITLAGPTNAIFK.A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1357.7969 2.66 42626 19383 2 1357.800462 679.9057 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3677.1 - 7.70E+06 - - - 2.5961 - 2.489 0.548 - 543.4 1 2 0 0.0035 13 0 0 0 4.23E+08 1.59E+08 - - - 5.4278 1 230117_WJC_METTL3_WT_vs_EV_F05.19385.19385.2 1.59E-06 22-Dec K.VVLEGPAPWGFR.L "sp|Q9NR12|PDLI7_HUMAN,tr|D6RF83|D6RF83_HUMAN,tr|D6RAN1|D6RAN1_HUMAN,tr|H7BYK4|H7BYK4_HUMAN,tr|D6RH06|D6RH06_HUMAN" 5 1326.7085 5.37 42628 19385 2 1326.711362 664.3615 PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1 5.97 3677.2 - 925735 - - - 2.1896 - 2.46 0.553 - 471.4 1 2 0 0.0029 12 0 0 0 1.43E+07 2.67E+06 - - - 5.493 1 230117_WJC_METTL3_WT_vs_EV_F05.19386.19386.2 1.04E-07 16-Nov K.WQALLVQIR.K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1125.6659 1.08 42629 19386 2 1125.668229 563.8402 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.75 3677.3 - 758097 - - - 2.101 - 2.22 0.449 - 548.5 1 2 0 0.0024 9 0 0 0 1.45E+07 1.34E+07 - - - 4.6638 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19389.19389.2 0.0243 20-Nov K.ILEAVTLVQLK[136.11].E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1233.7788 0.81 42632 19389 2 1233.779926 617.8967 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6 3677.6 - 348346 - - - 0.9329 - 2.284 0.393 - 256.9 1 2 0 0.0012 11 0 0 0 6.00E+06 7.37E+06 - - - 4.1777 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19392.19392.2 7.45E-05 22-Oct K.QVVPFVYQTIVK[136.11].D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1427.8268 1.77 42635 19392 2 1427.829629 714.9207 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 3677.8 - 299893 - - - 1.9897 - 1.943 0.512 - 254.8 1 2 0 0.0028 12 0 0 0 8.77E+06 4.97E+06 - - - 4.5695 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.19394.19394.2 1.47E-05 22-Oct K.LFGYEPTIYYPK[136.11].R "sp|Q8NCW5|NNRE_HUMAN,tr|A0A7P0Z426|A0A7P0Z426_HUMAN,tr|Q5T3I4|Q5T3I4_HUMAN,tr|A0A7P0T9Y2|A0A7P0T9Y2_HUMAN,tr|A0A7P0TAG8|A0A7P0TAG8_HUMAN,tr|Q5T3I3|Q5T3I3_HUMAN" 6 1497.7635 1.69 42637 19394 2 1497.768427 749.889 NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2 6 3678.1 - 218700 - - - 3.2769 - 2.149 0.435 - 235 1 2 0 0.0049 12 0 0 0 1.02E+07 6.03E+06 - - - 4.2652 1 230117_WJC_METTL3_WT_vs_EV_F05.19397.19397.2 6.18E-06 20-Oct K.VGEVTYVELFK[136.11].D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1290.6951 1.88 42639 19397 2 1290.695909 646.3548 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.53 3678.4 - 1.20E+06 - - - 0.6229 - 2.404 0.594 - 408.2 1 2 0 0.0008 11 0 0 0 9.08E+07 4.82E+07 - - - 5.8009 0.9943 230117_WJC_METTL3_WT_vs_EV_F05.19399.19399.2 0.0539 24-Apr R.IITLAGPTNAIFK[136.11].A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1365.8111 2.66 42641 19399 2 1365.813657 683.9128 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3678.6 - 1.39E+06 - - - 1.8451 - 0.864 0.305 - 50.4 1 2 0 0.0025 13 0 0 0 4.23E+08 1.59E+08 - - - 0.9178 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19401.19401.2 0.0458 14-Sep R.LWDFIENR.E "sp|Q9H000|MKRN2_HUMAN,tr|A0A7I2V5D2|A0A7I2V5D2_HUMAN,tr|A0A7I2YQI0|A0A7I2YQI0_HUMAN,tr|C9J494|C9J494_HUMAN" 4 1091.54 2.07 42643 19401 2 1091.540748 546.7773 Probable E3 ubiquitin-protein ligase makorin-2 OS=Homo sapiens OX=9606 GN=MKRN2 PE=1 SV=2 4.37 3678.7 - 612425 - - - 0.6908 - 2.083 0.413 - 306.4 1 2 0 0.0008 8 0 0 0 1.57E+07 7.61E+06 - - - 4.3043 0.9943 230117_WJC_METTL3_WT_vs_EV_F05.19405.19405.2 4.13E-05 14-Aug K.YWYLGPLK.L "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A0G2JLD0|A0A0G2JLD0_HUMAN,tr|E9PG39|E9PG39_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A0G2JLG5|A0A0G2JLG5_HUMAN,tr|A0A3B3ISZ0|A0A3B3ISZ0_HUMAN" 8 1038.5539 2.06 42645 19405 2 1038.56005 520.2842 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 8.5 3679.3 - 1.44E+06 - - - 5.966 - 1.526 0.427 - 259.9 1 2 0 0.0062 8 0 0 0 1.43E+07 6.98E+06 - - - 3.4676 0.9954 230117_WJC_METTL3_WT_vs_EV_F05.19406.19406.2 0.00849 22-Nov K.LILISTNGSFIR.L sp|Q6UXN9|WDR82_HUMAN 1 1332.7765 0.91 42646 19406 2 1332.784565 667.3955 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 9.75 3679.3 - 864507 - - - 6.0243 - 2.162 0.387 - 402.1 1 2 0 0.008 12 0 0 0 9.30E+06 1.02E+07 - - - 3.9256 1 230117_WJC_METTL3_WT_vs_EV_F05.19408.19408.2 1.51E-06 22-Dec K.QVVPFVYQTIVK.D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1419.8126 1.77 42648 19408 2 1419.815259 710.9136 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 3679.5 - 702916 - - - 1.8812 - 2.377 0.559 - 507.6 1 2 0 0.0027 12 0 0 0 8.77E+06 4.97E+06 - - - 5.4471 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.19409.19409.2 0.0193 22-Aug K.LILISTNGSFIR[166.11].L sp|Q6UXN9|WDR82_HUMAN 1 1342.7848 0.91 42649 19409 2 1342.787806 672.3997 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 9.75 3679.6 - 655835 - - - 2.2342 - 1.559 0.312 - 176.1 1 2 0 0.003 12 0 0 0 9.30E+06 1.02E+07 - - - 2.5128 0.8606 230117_WJC_METTL3_WT_vs_EV_F05.19411.19411.2 0.166 12-Jul L.PLFGLGR.L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 758.4439 1.21 42651 19411 2 758.444225 380.2292 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 10.18 3679.8 - 288614 - - - 0.4166 - 1.421 0.233 - 191.2 1 1 0 0.0003 7 0 0 0 3.31E+06 2.74E+06 - - - 1.8751 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19413.19413.2 0.00076 18-Sep K.LTLSALIDGK.N "sp|Q9Y277|VDAC3_HUMAN,sp|P21796|VDAC1_HUMAN" 2 1029.607 1.57 42653 19413 2 1029.609837 515.8108 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.84 3680 - 277027 - - - 2.7447 - 2.228 0.361 - 175.6 1 2 0 0.0028 10 0 0 0 3.97E+06 2.53E+06 - - - 3.9426 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.19419.19419.2 0.0928 16-Jul K.NLLNLDVIK[136.11].K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1048.6372 1 42657 19419 2 1048.640457 525.3259 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3680.7 - 2.89E+06 - - - 3.1098 - 1.661 0.256 - 140.6 1 2 0 0.0033 9 0 0 0 2.30E+07 2.31E+07 - - - 2.3988 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.19420.19420.2 0.085 16-Aug K.NLLNLDVIK.K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1040.623 1 42658 19420 2 1040.626546 521.3188 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3680.8 - 3.09E+06 - - - 3.4114 - 1.753 0.206 - 216.9 1 2 0 0.0036 9 0 0 0 2.30E+07 2.31E+07 - - - 2.1854 1 230117_WJC_METTL3_WT_vs_EV_F05.19421.19421.2 0.00496 18-Nov R.VLALEILPER[166.11].V sp|Q56A73|SPIN4_HUMAN 1 1161.6997 0.59 42659 19421 2 1161.702006 581.8571 Spindlin-4 OS=Homo sapiens OX=9606 GN=SPIN4 PE=1 SV=1 4.53 3680.9 - 615725 - - - 2.0022 - 2.498 0.456 - 429.1 1 2 0 0.0023 10 0 0 0 2.89E+06 4.92E+06 - - - 4.9637 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.19426.19426.2 9.06E-05 22-Oct R.LLTWVIGTGSPR[166.11].L sp|Q92616|GCN1_HUMAN 1 1308.7429 1.25 42664 19426 2 1308.749122 655.3787 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.75 3681.4 - 237569 - - - 4.7221 - 2.17 0.445 - 438.6 1 2 0 0.0062 12 0 0 0 4.91E+06 3.92E+06 - - - 4.3643 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.19427.19427.2 7.05E-05 28-Nov R.VGPDVVTDPAFLVTR[166.11].S sp|Q9NV31|IMP3_HUMAN 1 1594.8594 1.15 42665 19427 2 1594.866073 798.437 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3681.5 - 130952 - - - 4.1665 - 1.934 0.453 - 276.7 1 2 0 0.0066 15 0 0 0 4.06E+06 3.53E+06 - - - 4.0064 0.999 230117_WJC_METTL3_WT_vs_EV_F05.19431.19431.2 0.0567 16-Aug R.EILSPLFPR.N "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1070.6124 0.9 42667 19431 2 1070.614084 536.3135 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6.1 3682 - 511201 - - - 1.544 - 1.438 0.305 - 193.9 1 2 0 0.0017 9 0 0 0 1.74E+07 1.93E+07 - - - 2.3441 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19434.19434.2 0.0396 18-Sep K.IELFADVVPK.T "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 1129.6383 1.31 42670 19434 2 1129.6403 565.8264 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.37 3682.3 - 862327 - - - 1.7607 - 1.782 0.375 - 192.3 1 2 0 0.002 10 0 0 0 4.83E+07 3.69E+07 - - - 3.4228 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.19437.19437.2 0.00364 12-Jul R.EFEFLMR.Q sp|P85037|FOXK1_HUMAN 1 970.4582 2.59 42673 19437 2 970.45717 486.2364 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 4.53 3682.5 - 678539 - - - -1.1015 - 1.367 0.259 - 223.3 1 2 0 -0.0011 7 0 0 0 4.51E+06 1.75E+06 - - - 1.9442 1 230117_WJC_METTL3_WT_vs_EV_F05.19445.19445.2 9.51E-08 18/26 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 3.61 42681 19445 2 1541.847311 771.9299 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3683.4 - 231239 - - - 1.2757 - 3.032 0.469 - 1215.9 1 2 0 0.002 14 0 0 0 4.85E+07 1.35E+07 - - - 5.288 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19448.19448.2 1.60E-05 22-Oct K.LFGYEPTIYYPK.R "sp|Q8NCW5|NNRE_HUMAN,tr|A0A7P0Z426|A0A7P0Z426_HUMAN,tr|Q5T3I4|Q5T3I4_HUMAN,tr|A0A7P0T9Y2|A0A7P0T9Y2_HUMAN,tr|A0A7P0TAG8|A0A7P0TAG8_HUMAN,tr|Q5T3I3|Q5T3I3_HUMAN" 6 1489.7493 1.69 42683 19448 2 1489.751737 745.8819 NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2 6 3683.7 - 206589 - - - 1.6231 - 2.051 0.464 - 293.2 1 2 0 0.0024 12 0 0 0 1.02E+07 6.03E+06 - - - 4.3574 1 230117_WJC_METTL3_WT_vs_EV_F05.19450.19450.2 9.56E-05 13/20 R.LLESLDQLELR.V sp|O95816|BAG2_HUMAN 1 1327.7347 8.97 42684 19450 2 1327.741452 664.8746 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.14 3684 - 4.06E+06 - - - 5.062 - 2.585 0.466 - 583.3 1 2 0 0.0067 11 0 0 0 8.64E+07 9.63E+06 - - - 5.05 0.9846 230117_WJC_METTL3_WT_vs_EV_F05.19452.19452.2 0.287 18-Oct R.NALPALLIYK.G sp|Q13371|PHLP_HUMAN 1 1114.675 2.06 42686 19452 2 1114.678722 558.3448 Phosducin-like protein OS=Homo sapiens OX=9606 GN=PDCL PE=1 SV=3 8.59 3684.2 - 1.02E+06 - - - 3.3113 - 1.337 0.119 - 256.5 1 2 0 0.0037 10 0 0 0 4.26E+06 2.06E+06 - - - 0.7294 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.19453.19453.2 0.000923 18-Oct R.LIESLFTIQK[136.11].M "sp|Q12789|TF3C1_HUMAN,tr|H3BU37|H3BU37_HUMAN" 2 1198.7053 1.79 42687 19453 2 1198.711316 600.3599 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 6 3684.3 - 581569 - - - 5.0396 - 1.867 0.407 - 222.6 1 2 0 0.006 10 0 0 0 4.40E+06 2.46E+06 - - - 3.7879 1 230117_WJC_METTL3_WT_vs_EV_F05.19454.19454.2 4.73E-05 14/28 R.VGPDVVTDPAFLVTR.S sp|Q9NV31|IMP3_HUMAN 1 1584.8512 1.15 42688 19454 2 1584.85465 793.4329 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3684.5 - 470647 - - - 2.2034 - 2.462 0.561 - 444.9 1 2 0 0.0035 15 0 0 0 4.06E+06 3.53E+06 - - - 5.3985 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.19455.19455.3 7.08E-05 13/52 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 3.68 42689 19455 3 1541.852608 514.9557 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3684.6 - 458738 - - - 4.7112 - 2.112 0.344 - 156.3 1 2 0 0.0073 14 0 0 0 5.85E+06 1.59E+06 - - - 4.3601 1 230117_WJC_METTL3_WT_vs_EV_F05.19457.19457.2 2.72E-05 14/24 R.LSAYVSYGGLLMR[166.11].L "sp|P52434|RPAB3_HUMAN,tr|C9JLU1|C9JLU1_HUMAN" 2 1438.7518 0.97 42691 19457 2 1438.757174 720.3832 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4" 8.59 3684.9 - 372558 - - - 3.7407 - 2.477 0.501 - 608.7 1 2 0 0.0054 13 0 0 0 2.07E+06 2.13E+06 - - - 5.0677 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19459.19459.2 0.000117 24-Nov R.VESPVLPPVLVPR[166.11].H "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN" 2 1410.8474 1.79 42693 19459 2 1410.850388 706.431 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 5.97 3685.1 - 218215 - - - 2.1129 - 1.812 0.475 - 299.8 1 2 0 0.003 13 0 0 0 4.07E+06 2.28E+06 - - - 4.074 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.19460.19460.2 0.00492 24-Aug K.LVDSMGWELASVR.R "sp|O94761|RECQ4_HUMAN,tr|A0A087WTJ0|A0A087WTJ0_HUMAN,tr|A0A087X072|A0A087X072_HUMAN" 3 1461.7286 0.83 42694 19460 2 1461.732412 731.8716 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.37 3685.3 - 209609 - - - 2.6079 - 1.456 0.363 - 98.9 1 2 0 0.0038 13 0 0 0 1.97E+06 2.37E+06 - - - 2.6851 1 230117_WJC_METTL3_WT_vs_EV_F05.19461.19461.2 5.12E-05 24-Nov K.LVDSMGWELASVR[166.11].R "sp|O94761|RECQ4_HUMAN,tr|A0A087WTJ0|A0A087WTJ0_HUMAN,tr|A0A087X072|A0A087X072_HUMAN" 3 1471.7369 0.83 42695 19461 2 1471.739294 736.8757 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.37 3685.4 - 185425 - - - 1.647 - 2.258 0.511 - 317.5 1 2 0 0.0024 13 0 0 0 1.97E+06 2.37E+06 - - - 4.9049 1 230117_WJC_METTL3_WT_vs_EV_F05.19462.19462.2 2.58E-06 20-Dec K.IDAELVLPTIR.S "sp|O95985|TOP3B_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 2 1238.7234 0.85 42696 19462 2 1238.733009 620.369 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 4.37 3685.5 - 151991 - - - 7.7265 - 2.619 0.428 - 473.4 1 2 0 0.0096 11 0 0 0 1.29E+06 1.52E+06 - - - 4.8038 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19466.19466.2 0.000452 24-Oct R.LSAYVSYGGLLMR.L "sp|P52434|RPAB3_HUMAN,tr|C9JLU1|C9JLU1_HUMAN" 2 1428.7435 0.97 42699 19466 2 1428.74562 715.379 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4" 8.59 3686 - 217893 - - - 1.4684 - 2.215 0.436 - 287 1 2 0 0.0021 13 0 0 0 2.07E+06 2.13E+06 - - - 4.3017 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19468.19468.2 0.000751 18-Oct R.AEVVSLLLDR.K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1113.6394 1.3 42701 19468 2 1113.641031 557.827 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3686.1 - 1.98E+06 - - - 1.4879 - 2.09 0.445 - 400.1 1 2 0 0.0017 10 0 0 0 2.02E+07 1.55E+07 - - - 4.3849 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.19469.19469.2 0.0258 18-Sep K.IELFADVVPK[136.11].T "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 1137.6525 2.63 42702 19469 2 1137.656488 569.8335 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.37 3686.2 - 1.38E+06 - - - 3.4958 - 1.624 0.201 - 150.8 1 2 0 0.004 10 0 0 0 4.39E+07 1.67E+07 - - - 1.8778 1 230117_WJC_METTL3_WT_vs_EV_F05.19470.19470.2 3.10E-05 16/26 K.LLDAVDTYIPVPAR[166.11].D sp|P49411|EFTU_HUMAN 1 1551.8536 3.59 42703 19470 2 1551.856923 776.9341 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3686.2 - 1.27E+06 - - - 2.1323 - 2.975 0.543 - 977.9 1 2 0 0.0033 14 0 0 0 4.83E+07 1.35E+07 - - - 5.7865 1 230117_WJC_METTL3_WT_vs_EV_F05.19475.19475.2 6.13E-10 13/22 K.FATEDEAWAFVR.K sp|O60930|RNH1_HUMAN 1 1440.6674 0.56 42708 19475 2 1440.669319 721.341 Ribonuclease H1 OS=Homo sapiens OX=9606 GN=RNASEH1 PE=1 SV=2 4.14 3686.8 - 592955 - - - 1.3459 - 2.767 0.53 - 601 1 2 0 0.0019 12 0 0 0 2.31E+06 4.10E+06 - - - 5.6329 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19478.19478.2 0.0019 20-Sep K.VAPGFQFFATR.R sp|Q9NU22|MDN1_HUMAN 1 1239.64 0.9 42711 19478 2 1239.642474 620.8273 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 9.72 3687.1 - 274193 - - - 1.9611 - 1.508 0.345 - 200.2 1 2 0 0.0024 11 0 0 0 2.54E+06 2.83E+06 - - - 2.6997 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.19484.19484.2 2.62 12-Jun R.EIFDLIR.S "sp|Q9Y3D0|CIA2B_HUMAN,tr|H3BNV7|H3BNV7_HUMAN,tr|J3KS95|J3KS95_HUMAN" 3 904.5018 2.66 42716 19484 2 904.503253 453.2582 Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1 4.37 3687.7 - 2.95E+06 - - - 1.5865 - 1.422 0.174 - 198.8 1 2 0 0.0014 7 0 0 0 2.26E+07 8.50E+06 - - - 1.4412 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.19485.19485.2 0.221 16-Oct K.TFDPYIIIR[166.11].A sp|Q13601|KRR1_HUMAN 1 1146.6313 0.44 42717 19485 2 1146.634249 574.3229 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 5.5 3687.8 - 955438 - - - 2.6015 - 1.886 0.14 - 361.4 1 2 0 0.003 9 0 0 0 4.60E+06 1.04E+07 - - - 1.9096 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19486.19486.2 0.0058 18-Sep R.EALLAALGYK[136.11].N sp|Q9BU76|MMTA2_HUMAN 1 1055.6106 0.88 42718 19486 2 1055.612213 528.8126 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3687.9 - 837572 - - - 1.4835 - 2.212 0.316 - 253.7 1 2 0 0.0016 10 0 0 0 1.32E+07 1.50E+07 - - - 3.5905 1 230117_WJC_METTL3_WT_vs_EV_F05.19489.19489.2 0.018 13/20 R.VLITTLITAGR[166.11].L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1166.7262 0.86 42721 19489 2 1166.727967 584.3704 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3688.3 - 435099 - - - 1.4896 - 2.546 0.421 - 609.6 1 2 0 0.0017 11 0 0 0 6.17E+06 7.15E+06 - - - 4.6781 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19492.19492.2 0.00117 16-Sep K.GLMVLELPK.R "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 998.5834 3.55 42724 19492 2 998.584957 500.299 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6 3688.7 - 395640 - - - 1.5202 - 1.818 0.394 - 310.4 1 2 0 0.0015 9 0 0 0 2.19E+06 6.18E+05 - - - 3.6799 0.999 230117_WJC_METTL3_WT_vs_EV_F05.19494.19494.2 0.000734 20-Sep K.VAPGFQFFATR[166.11].R sp|Q9NU22|MDN1_HUMAN 1 1249.6483 1.24 42726 19494 2 1249.652059 625.8314 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 9.72 3688.9 - 312229 - - - 2.9976 - 1.645 0.362 - 313.1 1 2 0 0.0037 11 0 0 0 2.51E+06 2.02E+06 - - - 3.0601 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19495.19495.2 0.00477 20-Oct R.VLITTLITAGR.L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1156.718 0.86 42727 19495 2 1156.719889 579.3663 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3689.1 - 290556 - - - 1.6685 - 2.115 0.392 - 323.9 1 2 0 0.0019 11 0 0 0 6.17E+06 7.15E+06 - - - 3.9621 1 230117_WJC_METTL3_WT_vs_EV_F05.19496.19496.2 0.000135 16/26 R.LIVVLEGASLETVK.V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1469.8705 1.04 42728 19496 2 1469.875326 735.9425 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3689.2 - 224434 - - - 3.286 - 3.225 0.545 - 826.5 1 2 0 0.0048 14 0 0 0 1.54E+06 1.48E+06 - - - 6.0033 0.9805 230117_WJC_METTL3_WT_vs_EV_F05.19497.19497.2 1.11 12-Jun R.AFLPLLK.A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 800.516 1.27 42729 19497 2 800.517734 401.2653 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3689.3 - 206104 - - - 2.1524 - 1.144 0.089 - 185.5 1 2 0 0.0017 7 0 0 0 7.74E+06 6.07E+06 - - - 0.1241 1 230117_WJC_METTL3_WT_vs_EV_F05.19500.19500.2 1.87E-05 13/26 R.LIVVLEGASLETVK[136.11].V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1477.8847 1.04 42732 19500 2 1477.887234 739.9496 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3689.7 - 181214 - - - 1.7173 - 2.858 0.467 - 484.2 1 2 0 0.0025 14 0 0 0 1.54E+06 1.48E+06 - - - 5.1247 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.19503.19503.2 0.213 12-May R.EAYFWLR[166.11].Q sp|Q8TCJ2|STT3B_HUMAN 1 993.4948 0.95 42734 19503 2 993.49576 497.7547 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1 6.1 3690.1 - 500208 - - - 0.9945 - 1.26 0.25 - 84.8 1 2 0 0.001 7 0 0 0 2.73E+06 2.86E+06 - - - 1.6195 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19506.19506.2 0.0246 18-Sep R.EALLAALGYK.N sp|Q9BU76|MMTA2_HUMAN 1 1047.5964 0.58 42736 19506 2 1047.598028 524.8055 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3690.5 - 2.07E+06 - - - 1.5092 - 2.162 0.347 - 239.6 1 2 0 0.0016 10 0 0 0 1.34E+07 2.31E+07 - - - 3.7556 0.9635 230117_WJC_METTL3_WT_vs_EV_F05.19508.19508.2 0.152 20-Oct K.LGLDIEIATYR.R "sp|Q9NSB2|KRT84_HUMAN,sp|Q14533|KRT81_HUMAN,sp|P78386|KRT85_HUMAN,sp|Q9NSB4|KRT82_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|F5GYI5|F5GYI5_HUMAN" 8 1262.6871 8.78 42738 19508 2 1262.692928 632.3508 "Keratin, type II cuticular Hb4 OS=Homo sapiens OX=9606 GN=KRT84 PE=2 SV=2" 4.37 3690.8 - 1.10E+06 - - - 4.6528 - 1.261 0.146 - 177.4 1 2 0 0.0059 11 0 0 0 1.40E+07 1.59E+06 - - - 0.7449 0.9942 230117_WJC_METTL3_WT_vs_EV_F05.19509.19509.2 8.38E-05 18-Aug K.LFGYEMAEFK[136.11].V sp|Q9UKD2|MRT4_HUMAN 1 1241.5882 0.79 42739 19509 2 1241.59523 621.8014 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 4.53 3690.9 - 814274 - - - 5.6645 - 1.421 0.422 - 142.5 1 2 0 0.007 10 0 0 0 2.92E+06 3.70E+06 - - - 3.1364 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19511.19511.2 0.00053 18-Sep K.LFGYEMAEFK.V sp|Q9UKD2|MRT4_HUMAN 1 1233.574 0.79 42741 19511 2 1233.577794 617.7943 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 4.53 3691.2 - 561917 - - - 3.078 - 1.549 0.431 - 159.9 1 2 0 0.0038 10 0 0 0 2.92E+06 3.70E+06 - - - 3.4447 1 230117_WJC_METTL3_WT_vs_EV_F05.19513.19513.2 1.67E-05 22-Oct K.VIHDNFGIVEGL.M "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1311.6823 - 42743 19513 2 1311.68965 656.8484 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.35 3691.4 - 467802 - - - 5.602 - 2.264 0.493 - 374.3 1 1 0 0.0073 12 0 0 0 - - - - - 4.83 0.999 230117_WJC_METTL3_WT_vs_EV_F05.19516.19516.2 0.00167 22-Oct R.SQPAILLLTAAR.D "sp|Q5JTV8|TOIP1_HUMAN,tr|H0Y4R4|H0Y4R4_HUMAN,tr|J3KN66|J3KN66_HUMAN,tr|A0A0A0MSK5|A0A0A0MSK5_HUMAN" 4 1252.7503 1.79 42746 19516 2 1252.755048 627.3824 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=2 9.47 3691.8 - 399333 - - - 3.7725 - 2.092 0.406 - 364.9 1 2 0 0.0047 12 0 0 0 2.51E+06 1.40E+06 - - - 3.9804 0.9902 230117_WJC_METTL3_WT_vs_EV_F05.19517.19517.2 0.262 14-Jul R.LSFFGLEK.L "sp|Q9ULF5|S39AA_HUMAN,tr|E7EV45|E7EV45_HUMAN,tr|E7ENT5|E7ENT5_HUMAN" 3 939.5066 0.43 42747 19517 2 939.509425 470.7606 Zinc transporter ZIP10 OS=Homo sapiens OX=9606 GN=SLC39A10 PE=1 SV=2 6 3692 - 374709 - - - 3.0399 - 1.261 0.162 - 112.6 1 2 0 0.0029 8 0 0 0 1.47E+06 3.45E+06 - - - 0.9361 1 230117_WJC_METTL3_WT_vs_EV_F05.19520.19520.2 1.46E-08 26-Dec K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 2.31 42750 19520 2 1762.801616 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3692.4 - 229561 - - - 3.6964 - 2.282 0.665 - 459.6 1 2 0 0.0065 14 0 0 0 2.50E+06 1.08E+06 - - - 6.0211 0.988 230117_WJC_METTL3_WT_vs_EV_F05.19529.19529.2 1.3 12-Aug R.AFLPLLK[136.11].A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 808.5302 1.28 42758 19529 2 808.53285 405.2724 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3693.3 - 3.23E+06 - - - 3.2639 - 1.548 0.063 - 310.9 1 2 0 0.0026 7 0 0 0 7.77E+06 6.07E+06 - - - 0.89 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.19531.19531.2 0.000482 14-Oct R.YELALILK.A sp|P82932|RT06_HUMAN 1 961.5848 2.86 42760 19531 2 961.58861 481.7997 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3693.4 - 3.10E+06 - - - 3.9424 - 1.783 0.425 - 284.2 1 2 0 0.0038 8 0 0 0 1.30E+07 4.55E+06 - - - 3.923 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.19533.19533.2 0.0247 20-Dec R.LALVISELEGK[136.11].A "sp|Q12899|TRI26_HUMAN,tr|A2AE48|A2AE48_HUMAN" 2 1178.7002 1.44 42762 19533 2 1178.706755 590.3574 Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1 4.53 3693.6 - 1.60E+06 - - - 5.5697 - 2.557 0.306 - 463.6 1 2 0 0.0066 11 0 0 0 4.22E+06 2.93E+06 - - - 3.8388 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.19534.19534.2 0.0022 18-Sep R.TALYNYIFAK.K "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1202.6336 3.55 42763 19534 2 1202.635134 602.3241 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 8.17 3693.7 - 1.52E+06 - - - 1.3088 - 1.792 0.296 - 194.1 1 2 0 0.0016 10 0 0 0 4.24E+06 1.19E+06 - - - 2.855 0.9538 230117_WJC_METTL3_WT_vs_EV_F05.19535.19535.2 3.09 12-Jun R.EIFDLIR[166.11].S "sp|Q9Y3D0|CIA2B_HUMAN,tr|H3BNV7|H3BNV7_HUMAN,tr|J3KS95|J3KS95_HUMAN" 3 914.5101 2.68 42764 19535 2 914.513467 458.2623 Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1 4.37 3693.8 - 1.50E+06 - - - 3.6949 - 1.193 0.071 - 152.3 1 2 0 0.0034 7 0 0 0 2.25E+07 8.41E+06 - - - 0.1235 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.19536.19536.2 0.0262 14-Aug R.YELALILK[136.11].A sp|P82932|RT06_HUMAN 1 969.599 -1 42765 19536 2 969.602167 485.8068 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3693.9 - 1.48E+06 - - - 3.2467 - 1.587 0.344 - 163.5 1 2 0 0.0031 8 0 0 0 0.00E+00 0.00E+00 - - - 2.9737 1 230117_WJC_METTL3_WT_vs_EV_F05.19538.19538.2 1.58E-05 22-Sep K.VLLSPDYLPAMR.R sp|Q7Z6Z7|HUWE1_HUMAN 1 1373.7377 -1 42767 19538 2 1373.742447 687.8761 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.81 3694.2 - 1.23E+06 - - - 3.4497 - 2.067 0.517 - 261.6 1 2 0 0.0047 12 0 0 0 0.00E+00 0.00E+00 - - - 4.7686 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19540.19540.2 0.000446 22-Nov R.IEGVLLLGEPVR.W "sp|Q9BXW7|HDHD5_HUMAN,tr|A8MYZ9|A8MYZ9_HUMAN" 2 1293.7656 3.28 42769 19540 2 1293.766672 647.8901 Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Homo sapiens OX=9606 GN=HDHD5 PE=1 SV=1 4.53 3694.5 - 765478 - - - 0.8 - 2.508 0.394 - 638 1 2 0 0.001 12 0 0 0 4.88E+06 1.49E+06 - - - 4.3701 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.19542.19542.2 0.0484 14-Aug K.DFAIDIIK.S sp|Q15181|IPYR_HUMAN 1 933.5171 3.28 42771 19542 2 933.520913 467.7658 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 4.21 3694.7 - 652226 - - - 4.0481 - 1.354 0.338 - 190.7 1 2 0 0.0038 8 0 0 0 1.67E+06 5.09E+05 - - - 2.4503 0.987 230117_WJC_METTL3_WT_vs_EV_F05.19543.19543.2 0.224 14-Jun K.VLIVVPFR[166.11].E "sp|Q68CQ4|UTP25_HUMAN,tr|H7C2R4|H7C2R4_HUMAN" 2 951.6145 1.84 42772 19543 2 951.619153 476.8145 U3 small nucleolar RNA-associated protein 25 homolog OS=Homo sapiens OX=9606 GN=UTP25 PE=1 SV=2 9.72 3694.9 - 944828 - - - 4.8969 - 1.274 0.263 - 87.1 1 2 0 0.0047 8 0 0 0 2.46E+06 1.34E+06 - - - 1.7124 1 230117_WJC_METTL3_WT_vs_EV_F05.19544.19544.2 4.91E-09 26-Dec K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 2.31 42773 19544 2 1772.813324 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3695 - 437612 - - - 5.6148 - 2.45 0.675 - 506.4 1 2 0 0.01 14 0 0 0 2.50E+06 1.08E+06 - - - 6.2721 0.9511 230117_WJC_METTL3_WT_vs_EV_F05.19545.19545.2 0.428 24-Jul R.TLGLC[160.03]GTFNGNIR.D "sp|Q3ZCN5|OTOGL_HUMAN,tr|A0A2R8YF04|A0A2R8YF04_HUMAN" 2 1421.7085 999 42774 19545 2 1421.7169 711.8615 Otogelin-like protein OS=Homo sapiens OX=9606 GN=OTOGL PE=1 SV=5 7.91 3695.1 - 368916 - - - 5.8852 - 1.304 0.193 - 102.5 1 2 0 0.0084 13 0 0 0 2.24E+06 0.00E+00 - - - 1.1451 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.19549.19549.2 0.000676 13/18 R.IINDLLQSLR.S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1183.6925 2.18 42777 19549 2 1183.695496 592.8535 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3695.6 - 1.48E+07 - - - 2.5547 - 2.398 0.142 - 554 1 2 0 0.003 10 0 0 0 1.72E+08 7.92E+07 - - - 2.5302 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.19550.19550.2 1.75 18-Oct R.IINDLLQSLR[166.11].S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1193.7007 2.18 42778 19550 2 1193.70323 597.8576 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3695.7 - 7.55E+06 - - - 2.0843 - 2.2 0.123 - 296.4 1 2 0 0.0025 10 0 0 0 1.72E+08 7.92E+07 - - - 2.1495 1 230117_WJC_METTL3_WT_vs_EV_F05.19554.19554.2 0.000128 18-Oct R.LGLEDFESLK[136.11].V sp|Q15208|STK38_HUMAN 1 1157.606 0.54 42782 19554 2 1157.609561 579.8103 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3695.9 - 1.19E+06 - - - 3.115 - 2.298 0.477 - 233.5 1 2 0 0.0036 10 0 0 0 1.97E+08 3.66E+08 - - - 4.8855 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19560.19560.2 0.00168 20-Dec R.LALVISELEGK.A "sp|Q12899|TRI26_HUMAN,tr|A2AE48|A2AE48_HUMAN" 2 1170.686 1.44 42788 19560 2 1170.689019 586.3503 Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1 4.53 3696.4 - 553230 - - - 2.5874 - 2.246 0.333 - 336.5 1 2 0 0.003 11 0 0 0 4.22E+06 2.93E+06 - - - 3.6885 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.19561.19561.2 0.00131 14-Jul R.NYFGLFPR[166.11].V sp|Q8WUF5|IASPP_HUMAN 1 1022.5213 1.57 42789 19561 2 1022.519555 512.2679 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.75 3696.5 - 311557 - - - -1.7271 - 1.381 0.385 - 145.8 1 2 0 -0.0018 8 0 0 0 1.05E+07 6.71E+06 - - - 2.8576 0.9622 230117_WJC_METTL3_WT_vs_EV_F05.19562.19562.2 0.196 16-Jul R.GWAPVFLDR[166.11].E "sp|Q9Y5Y2|NUBP2_HUMAN,tr|H3BQR2|H3BQR2_HUMAN,tr|H3BRE1|H3BRE1_HUMAN,tr|H3BNF0|H3BNF0_HUMAN,tr|H3BNS4|H3BNS4_HUMAN" 5 1069.5584 -1 42790 19562 2 1069.564219 535.7865 Cytosolic Fe-S cluster assembly factor NUBP2 OS=Homo sapiens OX=9606 GN=NUBP2 PE=1 SV=1 5.84 3696.7 - 309436 - - - 5.4078 - 1.276 0.184 - 115.2 1 2 0 0.0058 9 0 0 0 0.00E+00 0.00E+00 - - - 1.1033 1 230117_WJC_METTL3_WT_vs_EV_F05.19564.19564.2 0.000405 13/22 Y.AIYELAVASFPK.K "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6R9C3|D6R9C3_HUMAN" 4 1307.7125 1.69 42792 19564 2 1307.714365 654.8635 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 6.05 3696.9 - 247785 - - - 1.3963 - 2.856 0.481 - 574.7 1 1 0 0.0018 12 0 0 0 2.66E+06 1.57E+06 - - - 5.3543 1 230117_WJC_METTL3_WT_vs_EV_F05.19571.19571.2 0.00072 18-Nov R.LGLEDFESLK.V sp|Q15208|STK38_HUMAN 1 1149.5918 0.54 42798 19571 2 1149.593253 575.8032 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3697.5 - 1.71E+06 - - - 1.3031 - 2.392 0.483 - 318.5 1 2 0 0.0015 10 0 0 0 1.97E+08 3.66E+08 - - - 5.0423 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19573.19573.2 0.000279 14-Aug R.GLDIYVWR.G sp|Q13045|FLII_HUMAN 1 1020.5393 1.33 42800 19573 2 1020.54044 511.2769 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3697.6 - 458806 - - - 1.1504 - 1.921 0.433 - 294.9 1 2 0 0.0012 8 0 0 0 6.35E+06 4.77E+06 - - - 4.2077 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.19583.19583.2 0.000619 20-Aug K.VLLAPLGDDFR[166.11].Y sp|Q16706|MA2A1_HUMAN 1 1224.6742 4.05 42808 19583 2 1224.678225 613.3444 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 4.21 3698.6 - 5.12E+06 - - - 3.2923 - 1.699 0.473 - 215.3 1 2 0 0.004 11 0 0 0 1.07E+08 2.63E+07 - - - 3.9672 0.9959 230117_WJC_METTL3_WT_vs_EV_F05.19584.19584.2 0.00728 16-Oct K.ALEVYDLIR.T "sp|Q9H5X1|CIA2A_HUMAN,tr|H0YKV4|H0YKV4_HUMAN" 2 1090.6023 1.41 42809 19584 2 1090.60847 546.3084 Cytosolic iron-sulfur assembly component 2A OS=Homo sapiens OX=9606 GN=CIAO2A PE=1 SV=1 4.37 3698.7 - 4.15E+06 - - - 5.6941 - 2.103 0.341 - 470.5 1 2 0 0.0062 9 0 0 0 1.53E+07 1.08E+07 - - - 3.7083 0.9953 230117_WJC_METTL3_WT_vs_EV_F05.19586.19586.2 1.15 16-Jun K.LQLSLADFR[166.11].R "sp|O00541|PESC_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 2 1071.5952 0.91 42811 19586 2 1071.59729 536.8049 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 5.84 3698.7 - 4.76E+06 - - - 1.9364 - 1.435 0.173 - 100.3 4 2 0 0.0021 9 0 0 0 2.15E+07 2.38E+07 - - - 1.0941 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19587.19587.2 0.574 16-Sep K.ALEVYDLIR[166.11].T "sp|Q9H5X1|CIA2A_HUMAN,tr|H0YKV4|H0YKV4_HUMAN" 2 1100.6105 1.41 42812 19587 2 1100.61227 551.3125 Cytosolic iron-sulfur assembly component 2A OS=Homo sapiens OX=9606 GN=CIAO2A PE=1 SV=1 4.37 3698.8 - 2.76E+06 - - - 1.5809 - 1.671 0.291 - 372.5 1 2 0 0.0017 9 0 0 0 1.53E+07 1.08E+07 - - - 2.6751 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.19590.19590.3 5.95E-06 Dec-76 K.FEAHPNDLYVEGLPENIPFR[166.11].S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2366.1571 3.78 42815 19590 3 2366.156681 789.7263 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3699 - 430013 - - - -0.1631 - 2.373 0.538 - 86.5 1 2 0 -0.0004 20 0 0 0 5.86E+06 1.55E+06 - - - 6.6345 0.9539 230117_WJC_METTL3_WT_vs_EV_F05.19592.19592.2 6.58E-05 26-Oct R.IMGIPEEEQMGLLR[166.11].V sp|P35579|MYH9_HUMAN 1 1624.8192 1.27 42817 19592 2 1625.822475 813.4169 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3699.3 - 344586 - - - 617.457 - 1.86 0.477 - 250.2 1 2 0 1.0033 14 0 0 0 6.38E+06 5.03E+06 - - - 3.8064 1 230117_WJC_METTL3_WT_vs_EV_F05.19595.19595.2 0.000334 13/32 R.IQEIIEQLDVTTSEYEK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2037.0154 -1 42820 19595 2 2037.022859 1019.515 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3699.6 - 235078 - - - 3.6706 - 3.23 0.554 - 378.2 1 2 0 0.0075 17 0 0 0 0.00E+00 0.00E+00 - - - 6.0131 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.19599.19599.2 0.0596 14-May R.LLFFAPTR.R sp|Q07820|MCL1_HUMAN 1 963.5542 4.09 42822 19599 2 963.556841 482.7844 Induced myeloid leukemia cell differentiation protein Mcl-1 OS=Homo sapiens OX=9606 GN=MCL1 PE=1 SV=3 9.75 3700.2 - 301375 - - - 2.7533 - 1.325 0.295 - 92.1 1 2 0 0.0027 8 0 0 0 7.28E+06 1.78E+06 - - - 2.0678 0.9779 230117_WJC_METTL3_WT_vs_EV_F05.19600.19600.2 0.618 18-Oct R.TEVVSLLLDR.K "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1143.6499 1.37 42823 19600 2 1143.658466 572.8322 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 3700.3 - 181037 - - - 7.456 - 1.979 0.255 - 312.2 1 2 0 0.0085 10 0 0 0 1.15E+07 8.42E+06 - - - 2.8271 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.19602.19602.2 9.22E-05 16-Sep K.GLFEVNPWK[136.11].R "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1096.5797 2.92 42825 19602 2 1096.580788 549.2971 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 6 3700.4 - 465897 - - - 1.0095 - 1.674 0.19 - 258.7 1 2 0 0.0011 9 0 0 0 2.91E+07 9.96E+06 - - - 1.9345 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.19606.19606.3 4.27E-05 14/68 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 2.01 42829 19606 3 1918.069311 640.3618 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3700.9 - 56443.8 - - - 2.9723 - 2.632 0.434 - 157.7 1 2 0 0.0057 18 0 0 0 4.44E+06 2.22E+06 - - - 5.7869 0.893 230117_WJC_METTL3_WT_vs_EV_F05.19608.19608.2 0.186 14-Sep L.IALALLAR.R sp|P43116|PE2R2_HUMAN 1 839.5593 999 42831 19608 2 839.561039 420.7869 Prostaglandin E2 receptor EP2 subtype OS=Homo sapiens OX=9606 GN=PTGER2 PE=1 SV=2 9.75 3701.2 - 48321.6 - - - 2.1035 - 1.881 0.158 - 365 1 1 0 0.0018 8 0 0 0 5.05E+06 0.00E+00 - - - 2.1129 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.19609.19609.2 0.0711 14-Jul R.LLFFAPTR[166.11].R sp|Q07820|MCL1_HUMAN 1 973.5625 4.05 42832 19609 2 973.56452 487.7885 Induced myeloid leukemia cell differentiation protein Mcl-1 OS=Homo sapiens OX=9606 GN=MCL1 PE=1 SV=3 9.75 3701.3 - 110547 - - - 2.118 - 1.456 0.259 - 139.6 1 2 0 0.0021 8 0 0 0 7.36E+06 1.82E+06 - - - 2.0864 1 230117_WJC_METTL3_WT_vs_EV_F05.19610.19610.2 0.00506 13/24 R.LENLGIPEEELLR.Q sp|Q01658|NC2B_HUMAN 1 1523.8195 2.53 42833 19610 2 1523.82108 762.917 Protein Dr1 OS=Homo sapiens OX=9606 GN=DR1 PE=1 SV=1 4.09 3701.4 - 0 - - - 1.0218 - 2.774 0.438 - 462 1 2 0 0.0016 13 0 0 0 4.47E+06 1.77E+06 - - - 4.8942 1 230117_WJC_METTL3_WT_vs_EV_F05.19611.19611.2 4.59E-08 26-Dec R.IMGIPEEEQMGLLR[166.11].V sp|P35579|MYH9_HUMAN 1 1624.8192 1.27 42834 19611 2 1624.830101 813.4169 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3701.5 - 345246 - - - 6.6974 - 2.141 0.586 - 318.1 1 2 0 0.0109 14 0 0 0 6.38E+06 5.03E+06 - - - 5.2762 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19612.19612.2 0.000712 22-Oct R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.18 42835 19612 2 1323.803656 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3701.7 - 56069.9 - - - 2.3289 - 1.756 0.417 - 258.1 1 2 0 0.0031 12 0 0 0 2.50E+06 2.13E+06 - - - 3.6014 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.19613.19613.2 0.0072 22-Sep R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.12 42836 19613 2 1315.788647 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3701.8 - 0 - - - 1.7282 - 1.777 0.34 - 169 1 2 0 0.0023 12 0 0 0 2.46E+06 2.20E+06 - - - 3.0643 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.19614.19614.2 0.0395 24-Sep R.LENLGIPEEELLR[166.11].Q sp|Q01658|NC2B_HUMAN 1 1533.8278 2.53 42837 19614 2 1533.830445 767.9212 Protein Dr1 OS=Homo sapiens OX=9606 GN=DR1 PE=1 SV=1 4.09 3701.9 - 0 - - - 1.729 - 1.97 0.317 - 113 1 2 0 0.0027 13 0 0 0 4.47E+06 1.77E+06 - - - 3.1217 0.9769 230117_WJC_METTL3_WT_vs_EV_F05.19615.19615.2 4.59 14-May K.SLLAGLLK[136.11].K "sp|P31751|AKT2_HUMAN,tr|M0R0P9|M0R0P9_HUMAN,tr|J3QKW1|J3QKW1_HUMAN,tr|J3QL45|J3QL45_HUMAN,tr|M0R283|M0R283_HUMAN,tr|M0QZW8|M0QZW8_HUMAN" 6 821.5466 0.79 42838 19615 2 821.548107 411.7806 RAC-beta serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=AKT2 PE=1 SV=2 8.47 3702 - 31309.5 - - - 1.8465 - 1.007 0.12 - 74.2 1 2 0 0.0015 8 0 0 0 1.79E+06 2.28E+06 - - - -0.0521 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.19617.19617.2 0.0596 Jul-32 R.IQEIIEQLDVTTSEYEK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2045.0296 -1 42840 19617 2 2045.032953 1023.5221 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3702.3 - 0 - - - 1.6484 - 1.448 0.292 - 77.5 1 2 0 0.0034 17 0 0 0 0.00E+00 0.00E+00 - - - 2.1068 1 230117_WJC_METTL3_WT_vs_EV_F05.19624.19624.2 1.58E-08 13/26 R.IMGIPEEEQMGLLR.V sp|P35579|MYH9_HUMAN 1 1614.8109 1.27 42846 19624 2 1614.813721 808.4128 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3703.1 - 1.68E+06 - - - 1.7166 - 2.451 0.639 - 408.9 1 2 0 0.0028 14 0 0 0 6.38E+06 5.03E+06 - - - 6.0095 1 230117_WJC_METTL3_WT_vs_EV_F05.19627.19627.2 0.00235 20-Oct R.LFEAEAQDLFR.D sp|Q9H223|EHD4_HUMAN 1 1337.6616 2.43 42849 19627 2 1337.661992 669.8381 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3703.2 - 979269 - - - 0.3185 - 2.417 0.488 - 343.6 1 2 0 0.0004 11 0 0 0 1.76E+07 7.24E+06 - - - 5.0327 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.19628.19628.2 0.0152 14-Aug K.VAIIIPFR[166.11].N "sp|P15291|B4GT1_HUMAN,sp|O43286|B4GT5_HUMAN,tr|Q86XA6|Q86XA6_HUMAN" 3 937.5988 0.85 42850 19628 2 937.598799 469.8067 "Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5" 9.72 3703.3 - 858298 - - - -0.0469 - 1.639 0.295 - 267.7 1 2 0 0 8 0 0 0 4.16E+06 4.87E+06 - - - 2.71 1 230117_WJC_METTL3_WT_vs_EV_F05.19630.19630.2 0.000123 14/22 R.LPADTC[160.03]LLEFAR.L "sp|Q8NF37|PCAT1_HUMAN,tr|A0A0G2JQ62|A0A0G2JQ62_HUMAN,tr|A0A0G2JRI7|A0A0G2JRI7_HUMAN" 3 1404.7071 1.42 42852 19630 2 1404.711536 703.3608 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 4.37 3703.4 - 773117 - - - 3.1323 - 2.549 0.529 - 836.7 1 2 0 0.0044 12 0 0 0 4.66E+06 3.29E+06 - - - 5.4088 1 230117_WJC_METTL3_WT_vs_EV_F05.19634.19634.2 9.49E-07 22-Dec K.YGLEGTVFFEEK.D "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1417.6765 4.32 42856 19634 2 1417.673417 709.8456 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.25 3703.7 - 473309 - - - -2.2085 - 2.539 0.593 - 468.3 1 2 0 -0.0031 12 0 0 0 5.40E+06 1.25E+06 - - - 5.8716 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.19635.19635.2 0.128 14-Sep R.NLFEQLVR[166.11].R "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VV47|F8VV47_HUMAN,tr|F8VUW9|F8VUW9_HUMAN,tr|F8VWY4|F8VWY4_HUMAN,tr|F8VRD2|F8VRD2_HUMAN,tr|F8VVY0|F8VVY0_HUMAN,tr|F8VZ66|F8VZ66_HUMAN,tr|F8VWX0|F8VWX0_HUMAN,tr|F8VS54|F8VS54_HUMAN,tr|F8W0L1|F8W0L1_HUMAN,tr|F8VVE5|F8VVE5_HUMAN,tr|F8VV39|F8VV39_HUMAN,tr|F8VXH1|F8VXH1_HUMAN" 13 1027.569 2.42 42857 19635 2 1027.571056 514.7918 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 6 3703.8 - 349008 - - - 2.0008 - 1.4 0.201 - 278.4 1 2 0 0.0021 8 0 0 0 8.27E+06 3.41E+06 - - - 1.5397 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.19639.19639.2 0.00611 14-Sep R.NLFEQLVR.R "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VV47|F8VV47_HUMAN,tr|F8VUW9|F8VUW9_HUMAN,tr|F8VWY4|F8VWY4_HUMAN,tr|F8VRD2|F8VRD2_HUMAN,tr|F8VVY0|F8VVY0_HUMAN,tr|F8VZ66|F8VZ66_HUMAN,tr|F8VWX0|F8VWX0_HUMAN,tr|F8VS54|F8VS54_HUMAN,tr|F8W0L1|F8W0L1_HUMAN,tr|F8VVE5|F8VVE5_HUMAN,tr|F8VV39|F8VV39_HUMAN,tr|F8VXH1|F8VXH1_HUMAN" 13 1017.5607 2.58 42860 19639 2 1017.562079 509.7876 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 6 3704.3 - 1.94E+06 - - - 1.3257 - 1.673 0.261 - 341.4 1 2 0 0.0014 8 0 0 0 8.80E+06 3.41E+06 - - - 2.5204 0.9903 230117_WJC_METTL3_WT_vs_EV_F05.19640.19640.2 0.563 14-Aug K.VAIIIPFR.N "sp|P15291|B4GT1_HUMAN,sp|O43286|B4GT5_HUMAN,tr|Q86XA6|Q86XA6_HUMAN" 3 927.5906 0.19 42861 19640 2 927.595339 464.8026 "Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5" 9.72 3704.4 - 1.82E+06 - - - 5.138 - 1.871 0.164 - 258.7 1 2 0 0.0048 8 0 0 0 4.75E+06 2.44E+07 - - - 2.1402 1 230117_WJC_METTL3_WT_vs_EV_F05.19642.19642.2 0.0813 20-Dec R.LFEAEAQDLFR[166.11].D sp|Q9H223|EHD4_HUMAN 1 1347.6698 2.43 42863 19642 2 1347.671726 674.8422 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3704.7 - 1.24E+06 - - - 1.4024 - 2.481 0.495 - 504.7 1 2 0 0.0019 11 0 0 0 1.76E+07 7.24E+06 - - - 5.1546 1 230117_WJC_METTL3_WT_vs_EV_F05.19644.19644.2 0.000622 15/22 R.LPADTC[160.03]LLEFAR[166.11].L "sp|Q8NF37|PCAT1_HUMAN,tr|A0A0G2JQ62|A0A0G2JQ62_HUMAN,tr|A0A0G2JRI7|A0A0G2JRI7_HUMAN" 3 1414.7154 1.42 42865 19644 2 1414.717143 708.365 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 4.37 3704.9 - 754307 - - - 1.2278 - 2.715 0.476 - 1112.5 1 2 0 0.0017 12 0 0 0 4.66E+06 3.29E+06 - - - 5.1842 0.9959 230117_WJC_METTL3_WT_vs_EV_F05.19645.19645.2 0.0293 16-Aug K.STLINTLFK.S "sp|Q9UHD8|SEPT9_HUMAN,tr|K7EKN4|K7EKN4_HUMAN,tr|K7EN52|K7EN52_HUMAN,tr|K7EQD7|K7EQD7_HUMAN,tr|K7ER52|K7ER52_HUMAN,tr|A0A6Q8PHC2|A0A6Q8PHC2_HUMAN,tr|K7ER14|K7ER14_HUMAN,tr|K7EIE4|K7EIE4_HUMAN,tr|K7EJZ2|K7EJZ2_HUMAN,tr|K7ENQ5|K7ENQ5_HUMAN,tr|K7EL40|K7EL40_HUMAN,tr|K7EK18|K7EK18_HUMAN" 12 1035.5964 0.72 42866 19645 2 1035.6005 518.8055 Septin-9 OS=Homo sapiens OX=9606 GN=SEPTIN9 PE=1 SV=2 8.47 3705.1 - 740997 - - - 3.9137 - 1.339 0.309 - 162.3 1 2 0 0.0041 9 0 0 0 1.67E+06 2.32E+06 - - - 2.1666 0.9397 230117_WJC_METTL3_WT_vs_EV_F05.19646.19646.2 2.03 12-Jun K.LTFLDLR[166.11].N "sp|Q9H9A6|LRC40_HUMAN,tr|X6R5P2|X6R5P2_HUMAN" 2 886.5152 1.49 42867 19646 2 886.518408 444.2649 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.84 3705.2 - 711894 - - - 3.6491 - 1.17 0.07 - 98.9 2 2 0 0.0032 7 0 0 0 6.77E+06 4.55E+06 - - - -0.08 0.9746 230117_WJC_METTL3_WT_vs_EV_F05.19647.19647.2 0.0406 12-Jul K.NFIQWIR.T sp|Q6NSI4|RADX_HUMAN 1 975.529 0.23 42868 19647 2 975.534201 488.7718 RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2 9.75 3705.3 - 604511 - - - 5.2946 - 1.521 0.135 - 190.8 1 2 0 0.0052 7 0 0 0 2.75E+06 1.19E+07 - - - 1.3653 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.19648.19648.2 0.00211 20-Sep R.VAQFLVIYAPR[166.11].R sp|Q9H2M9|RBGPR_HUMAN 1 1285.7422 1.91 42869 19648 2 1285.746169 643.8784 Rab3 GTPase-activating protein non-catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP2 PE=1 SV=1 8.72 3705.4 - 527086 - - - 3.0768 - 1.904 0.207 - 95.5 1 2 0 0.004 11 0 0 0 3.00E+06 1.57E+06 - - - 2.3107 1 230117_WJC_METTL3_WT_vs_EV_F05.19649.19649.2 3.12E-08 16/28 R.VMAGALEGDIFIGPK.A "sp|P61163|ACTZ_HUMAN,sp|P42025|ACTY_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 4 1516.796 1.48 42870 19649 2 1516.79856 759.4053 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4.37 3705.6 - 474652 - - - 1.7201 - 2.849 0.592 - 851.5 1 2 0 0.0026 15 0 0 0 1.56E+07 1.06E+07 - - - 5.9867 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.19650.19650.2 0.018 20-Jul K.NLIEMSELEIK.H sp|Q9Y5X3|SNX5_HUMAN 1 1317.685 31.3 42871 19650 2 1317.69012 659.8498 Sorting nexin-5 OS=Homo sapiens OX=9606 GN=SNX5 PE=1 SV=1 4.25 3705.7 - 426986 - - - 3.8826 - 1.656 0.31 - 134.5 1 2 0 0.0051 11 0 0 0 3.68E+06 1.18E+05 - - - 2.6936 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19652.19652.2 0.000783 22-Aug K.QYPISLVLAPTR.E "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1356.7765 -1 42873 19652 2 1356.777426 679.3955 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.75 3706 - 381156 - - - 0.656 - 1.634 0.434 - 133.3 1 2 0 0.0009 12 0 0 0 0.00E+00 0.00E+00 - - - 3.5382 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.19653.19653.2 0.00765 22-Oct R.LLSAGQLLFQGR[166.11].A sp|Q567V2|M17L2_HUMAN 1 1311.7538 -1 42874 19653 2 1311.755113 656.8842 Mpv17-like protein 2 OS=Homo sapiens OX=9606 GN=MPV17L2 PE=1 SV=2 9.75 3706.1 - 263869 - - - 0.9697 - 1.739 0.176 - 219.4 1 2 0 0.0013 12 0 0 0 0.00E+00 0.00E+00 - - - 1.7964 1 230117_WJC_METTL3_WT_vs_EV_F05.19656.19656.2 9.18E-05 24-Oct R.LGIGMDTC[160.03]VIPLR.H "sp|P49903|SPS1_HUMAN,tr|Q5T5U6|Q5T5U6_HUMAN" 2 1443.7578 -1 42877 19656 2 1443.766373 722.8862 "Selenide, water dikinase 1 OS=Homo sapiens OX=9606 GN=SEPHS1 PE=1 SV=2" 5.83 3706.5 - 191839 - - - 5.9435 - 2.289 0.504 - 360.4 1 2 0 0.0086 13 0 0 0 0.00E+00 0.00E+00 - - - 4.8862 1 230117_WJC_METTL3_WT_vs_EV_F05.19659.19659.2 0.000404 18-Nov K.VAEITELILK[136.11].A "sp|Q06265|EXOS9_HUMAN,tr|D6R905|D6R905_HUMAN,tr|H0Y9L5|H0Y9L5_HUMAN,tr|D6RIY6|D6RIY6_HUMAN" 4 1135.6944 1.1 42879 19659 2 1135.699817 568.8545 Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3 4.53 3706.8 - 1.33E+06 - - - 4.7909 - 2.338 0.472 - 395.9 1 2 0 0.0054 10 0 0 0 1.69E+07 1.55E+07 - - - 4.8961 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.19663.19663.2 0.49 14-Aug K.LLILALER[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 949.62 1.32 42883 19663 2 949.621549 475.8173 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6 3707.1 - 1.41E+06 - - - 1.6596 - 1.788 0.265 - 219.3 1 2 0 0.0016 8 0 0 0 5.55E+07 4.22E+07 - - - 2.7504 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19664.19664.2 0.000834 18-Oct K.LLDEVFFSEK.L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1225.6231 1.61 42884 19664 2 1225.624024 613.8188 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3707.2 - 1.40E+06 - - - 0.7906 - 2.182 0.379 - 263.4 1 2 0 0.001 10 0 0 0 2.97E+08 1.84E+08 - - - 4.0179 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19665.19665.2 0.000422 18-Sep R.C[160.03]LFQSPLFAK.A sp|Q86X55|CARM1_HUMAN 1 1209.6216 10.93 42885 19665 2 1209.622831 605.8181 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 8.22 3707.2 - 1.24E+06 - - - 1.0044 - 1.508 0.485 - 207.4 1 2 0 0.0012 10 0 0 0 5.57E+06 5.10E+05 - - - 3.7695 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.19666.19666.2 0.0734 16-Sep R.VLLPVLLNK.N sp|O00186|STXB3_HUMAN 1 1007.6743 2.04 42886 19666 2 1007.675754 504.8444 Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2 8.72 3707.3 - 1.19E+06 - - - 1.4399 - 1.824 0.283 - 234.9 1 2 0 0.0015 9 0 0 0 7.77E+06 3.81E+06 - - - 2.8696 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19667.19667.2 0.000259 24-Nov K.IYVDDGLISLQVK.Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1461.8079 1.31 42887 19667 2 1461.810683 731.9112 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3707.5 - 930030 - - - 1.9065 - 2.045 0.455 - 248.3 1 2 0 0.0028 13 0 0 0 6.29E+06 4.80E+06 - - - 4.2368 1 230117_WJC_METTL3_WT_vs_EV_F05.19669.19669.2 2.14E-06 13/24 K.IYVDDGLISLQVK[136.11].Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1469.8221 1.31 42889 19669 2 1469.824401 735.9183 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3707.7 - 757768 - - - 1.5682 - 2.514 0.58 - 399.5 1 2 0 0.0023 13 0 0 0 6.29E+06 4.80E+06 - - - 5.6902 1 230117_WJC_METTL3_WT_vs_EV_F05.19670.19670.2 0.000219 13/24 K.LLC[160.03]DSVVLQPYLR.E "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN,tr|H0YBB4|H0YBB4_HUMAN" 3 1574.8491 4.02 42890 19670 2 1574.852802 788.4318 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.83 3707.8 - 688524 - - - 2.3825 - 2.566 0.523 - 677.2 1 2 0 0.0038 13 0 0 0 3.15E+06 7.83E+05 - - - 5.3213 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.19671.19671.2 0.0037 16-Oct K.LFSNVLILK.S "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1045.6536 1.26 42891 19671 2 1045.655075 523.8341 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.75 3707.9 - 685672 - - - 1.4412 - 1.49 0.386 - 236.2 1 2 0 0.0015 9 0 0 0 6.53E+06 5.17E+06 - - - 3.0452 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.19672.19672.2 0.124 16-Jul K.LFSNVLILK[136.11].S "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1053.6678 1.26 42892 19672 2 1053.669252 527.8412 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.75 3708 - 664772 - - - 1.4084 - 1.206 0.299 - 104.1 1 2 0 0.0015 9 0 0 0 6.53E+06 5.17E+06 - - - 1.7908 0.9635 230117_WJC_METTL3_WT_vs_EV_F05.19673.19673.2 0.00572 14-Aug F.GPILNFLR.H "sp|Q8N5Z5|KCD17_HUMAN,tr|H7C323|H7C323_HUMAN,tr|B0QYB2|B0QYB2_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 5 928.5494 0.61 42893 19673 2 928.550779 465.282 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 9.75 3708.1 - 558262 - - - 1.4453 - 1.773 0.342 - 278.8 1 1 0 0.0013 8 0 0 0 1.38E+07 2.28E+07 - - - 3.2937 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.19675.19675.2 0.000326 22-Sep K.ALSTFFVENSLR[166.11].T sp|Q9Y2V7|COG6_HUMAN 1 1392.7277 1.57 42895 19675 2 1392.73085 697.3711 Conserved oligomeric Golgi complex subunit 6 OS=Homo sapiens OX=9606 GN=COG6 PE=1 SV=2 6.05 3708.3 - 323760 - - - 2.2725 - 1.832 0.329 - 292.9 1 2 0 0.0032 12 0 0 0 2.21E+06 1.41E+06 - - - 3.0629 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19678.19678.2 0.00463 18-Jul K.VAEITELILK.A "sp|Q06265|EXOS9_HUMAN,tr|D6R905|D6R905_HUMAN,tr|H0Y9L5|H0Y9L5_HUMAN,tr|D6RIY6|D6RIY6_HUMAN" 4 1127.6802 1.08 42897 19678 2 1127.68153 564.8474 Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3 4.53 3708.6 - 455674 - - - 1.2007 - 1.713 0.382 - 92.2 1 2 0 0.0014 10 0 0 0 1.65E+07 1.53E+07 - - - 3.3644 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19679.19679.2 0.0165 18-Sep K.LLDEVFFSEK[136.11].L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1233.6373 1.61 42898 19679 2 1233.638899 617.8259 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3708.6 - 2.68E+06 - - - 1.3326 - 2.008 0.393 - 183.1 1 2 0 0.0016 10 0 0 0 2.97E+08 1.84E+08 - - - 3.8891 0.998 230117_WJC_METTL3_WT_vs_EV_F05.19684.19684.2 0.0595 16-Jul K.VIPTLALLK[136.11].D sp|O14530|TXND9_HUMAN 1 974.662 2.19 42903 19684 2 974.663323 488.3383 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 8.72 3709.2 - 453985 - - - 1.4046 - 1.045 0.343 - 79.8 1 2 0 0.0014 9 0 0 0 1.69E+07 7.73E+06 - - - 1.7013 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.19686.19686.2 0.0768 14-Aug R.YILATLLK.E "sp|Q6PI48|SYDM_HUMAN,tr|A0A3B3IS01|A0A3B3IS01_HUMAN,tr|A0A3B3ISK7|A0A3B3ISK7_HUMAN,tr|A0A3B3IT01|A0A3B3IT01_HUMAN" 4 933.5899 1.24 42905 19686 2 933.590178 467.8022 "Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2 PE=1 SV=1" 8.59 3709.4 - 350633 - - - 0.2924 - 1.27 0.28 - 171.5 1 2 0 0.0003 8 0 0 0 3.52E+06 2.84E+06 - - - 1.8299 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.19690.19690.2 0.0124 20-Nov K.TAAFALPVLER.L "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 1186.671 0.92 42909 19690 2 1186.676112 594.3428 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.66 3709.9 - 190182 - - - 4.3003 - 2.23 0.434 - 451.8 1 2 0 0.0051 11 0 0 0 1.10E+07 1.19E+07 - - - 4.4145 0.9952 230117_WJC_METTL3_WT_vs_EV_F05.19697.19697.2 4.77 14-Aug K.DFLIPIGK.A "sp|P11177|ODPB_HUMAN,tr|F8WF02|F8WF02_HUMAN,tr|C9J634|C9J634_HUMAN" 3 901.5273 1.98 42915 19697 2 901.527442 451.7709 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 5.84 3710.7 - 2.58E+06 - - - 0.1531 - 1.606 0.105 - 279.9 1 2 0 0.0001 8 0 0 0 1.04E+08 5.24E+07 - - - 1.2453 1 230117_WJC_METTL3_WT_vs_EV_F05.19698.19698.2 8.99E-07 22-Dec R.IYGLGSLALYEK[136.11].A sp|P36542|ATPG_HUMAN 1 1333.7373 1.51 42916 19698 2 1333.738607 667.8759 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6 3710.7 - 1.19E+06 - - - 0.977 - 2.344 0.51 - 391.9 1 2 0 0.0013 12 0 0 0 3.76E+08 2.49E+08 - - - 5.0488 1 230117_WJC_METTL3_WT_vs_EV_F05.19702.19702.2 1.17E-06 22-Dec K.ALEDAFLAIDAK.L sp|O15355|PPM1G_HUMAN 1 1275.6711 2.97 42918 19702 2 1275.670674 638.8428 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.03 3711.3 - 1.53E+06 - - - -0.3089 - 2.569 0.528 - 385.5 1 2 0 -0.0004 12 0 0 0 5.61E+07 1.89E+07 - - - 5.4232 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.19703.19703.2 0.0674 16-Jul K.VIPTLALLK.D sp|O14530|TXND9_HUMAN 1 966.6478 2.19 42919 19703 2 966.647983 484.3312 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 8.72 3711.3 - 1.63E+06 - - - 0.2369 - 1.317 0.296 - 104 1 2 0 0.0002 9 0 0 0 1.69E+07 7.73E+06 - - - 2.0238 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19704.19704.2 0.00271 18-Aug K.SVLIGEFLEK.V "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1133.6332 0.85 42920 19704 2 1133.633977 567.8239 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 3711.4 - 1.31E+06 - - - 0.6625 - 1.845 0.421 - 195.2 1 2 0 0.0008 10 0 0 0 1.12E+08 1.32E+08 - - - 3.8599 1 230117_WJC_METTL3_WT_vs_EV_F05.19705.19705.2 0.000263 20-Dec R.EVWALVQAGIR.D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1240.6928 1.36 42921 19705 2 1240.694469 621.3537 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.1 3711.5 - 982866 - - - 1.3396 - 2.405 0.456 - 522.7 1 2 0 0.0017 11 0 0 0 1.57E+07 1.15E+07 - - - 4.7825 0.9949 230117_WJC_METTL3_WT_vs_EV_F05.19711.19711.2 0.0742 18-Sep R.TLLLDGNPFR[166.11].V sp|Q9H9A6|LRC40_HUMAN 1 1154.6323 0.51 42926 19711 2 1154.632111 578.3234 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.5 3712.3 - 859630 - - - -0.1879 - 1.291 0.216 - 208.8 1 2 0 -0.0002 10 0 0 0 1.72E+07 3.39E+07 - - - 1.3493 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.19713.19713.2 0.0488 16-May K.TMTLFSALR[166.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 1048.5615 1.05 42927 19713 2 1048.564504 525.288 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.41 3712.5 - 736115 - - - 2.8916 - 1.207 0.291 - 100.8 1 2 0 0.003 9 0 0 0 1.29E+07 1.23E+07 - - - 1.7337 1 230117_WJC_METTL3_WT_vs_EV_F05.19715.19715.3 6.71E-10 16/76 R.LALVTGGEIASTFDHPELVK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2096.1154 57.16 42929 19715 3 2096.11928 699.7124 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 3712.7 - 525772 - - - 1.8649 - 3.279 0.547 - 263.6 1 2 0 0.0039 20 0 0 0 6.63E+06 1.16E+05 - - - 7.5184 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.19720.19720.2 0.0183 16-Aug K.TLFPLIEAK.K sp|P13010|XRCC5_HUMAN 1 1030.6063 0.99 42932 19720 2 1030.608752 516.3104 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.66 3713.2 - 3.31E+06 - - - 2.3957 - 1.48 0.364 - 203.5 1 2 0 0.0025 9 0 0 0 2.65E+08 2.67E+08 - - - 2.8629 0.954 230117_WJC_METTL3_WT_vs_EV_F05.19722.19722.2 0.0297 12-Aug L.PDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 956.4744 2.5 42934 19722 2 956.474224 479.2445 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 6.27 3713.4 - 737445 - - - -0.1537 - 1.774 0.38 - 262.7 1 1 0 -0.0001 7 0 0 0 7.00E+07 2.80E+07 - - - 3.664 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.19723.19723.2 0.0135 24-Sep R.GLLPGLLPAPADK.L sp|Q6P2E9|EDC4_HUMAN 1 1260.7442 1.72 42935 19723 2 1260.742001 631.3794 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 5.84 3713.5 - 593731 - - - -1.7236 - 1.897 0.334 - 197.4 1 2 0 -0.0022 13 0 0 0 1.29E+07 7.51E+06 - - - 3.1505 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.19724.19724.2 0.0125 24-Sep R.GLLPGLLPAPADK[136.11].L sp|Q6P2E9|EDC4_HUMAN 1 1268.7584 1.72 42936 19724 2 1268.759772 635.3865 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 5.84 3713.6 - 364686 - - - 1.1019 - 1.98 0.155 - 246.7 1 2 0 0.0014 13 0 0 0 1.29E+07 7.51E+06 - - - 1.9386 0.992 230117_WJC_METTL3_WT_vs_EV_F05.19729.19729.2 0.0804 20-Sep R.EVWALVQAGIR[166.11].D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1250.7011 1.26 42938 19729 2 1250.700461 626.3578 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.1 3714.4 - 386612 - - - -0.4925 - 1.308 0.185 - 101.1 1 2 0 -0.0006 11 0 0 0 1.57E+07 1.24E+07 - - - 1.1336 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19730.19730.2 0.000693 22-Dec R.TFLESPLDVGIK.L "sp|Q8TEU7|RPGF6_HUMAN,tr|B7Z7Y1|B7Z7Y1_HUMAN,tr|E9PCH4|E9PCH4_HUMAN,tr|D6RE77|D6RE77_HUMAN,tr|A0A5F9ZHG7|A0A5F9ZHG7_HUMAN" 5 1317.718 0.08 42939 19730 2 1317.720599 659.8663 Rap guanine nucleotide exchange factor 6 OS=Homo sapiens OX=9606 GN=RAPGEF6 PE=1 SV=2 4.37 3714.5 - 94057.8 - - - 1.9587 - 2.274 0.444 - 367.6 1 2 0 0.0026 12 0 0 0 2.68E+07 3.47E+08 - - - 4.4812 1 230117_WJC_METTL3_WT_vs_EV_F05.19735.19735.2 0.000209 18-Dec R.GPILLPYQFR.M "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1202.6812 1.22 42943 19735 2 1202.681623 602.3479 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 8.75 3715.1 - 990458 - - - 0.3692 - 2.226 0.49 - 647.8 1 2 0 0.0004 10 0 0 0 1.64E+07 1.34E+07 - - - 4.8936 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19737.19737.2 0.00243 18-Aug K.ELLGQGLLLR[166.11].S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1120.6844 0.83 42944 19737 2 1120.685768 561.3495 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3715.4 - 8.68E+06 - - - 1.2528 - 2.057 0.313 - 230.1 1 2 0 0.0014 10 0 0 0 9.74E+07 1.17E+08 - - - 3.3656 0.9885 230117_WJC_METTL3_WT_vs_EV_F05.19738.19738.2 0.0804 18-Oct R.GPILLPYQFR[166.11].M "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1212.6894 1.22 42945 19738 2 1212.698037 607.352 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 8.75 3715.5 - 829155 - - - 7.0818 - 2.033 0.331 - 372.1 1 2 0 0.0086 10 0 0 0 1.64E+07 1.34E+07 - - - 3.4635 0.989 230117_WJC_METTL3_WT_vs_EV_F05.19742.19742.2 0.648 14-Jun K.QFLLFTER.F sp|Q68CQ4|UTP25_HUMAN 1 1052.5655 999 42949 19742 2 1052.566761 527.29 U3 small nucleolar RNA-associated protein 25 homolog OS=Homo sapiens OX=9606 GN=UTP25 PE=1 SV=2 6 3716 - 399672 - - - 1.2161 - 1.19 0.114 - 79.6 1 2 0 0.0013 8 0 0 0 2.95E+06 0.00E+00 - - - 0.4072 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19743.19743.2 0.099 22-Dec K.LANILFTQELAR.R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1387.7823 1.46 42950 19743 2 1387.782116 694.8985 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3716.2 - 247376 - - - -0.1686 - 2.414 0.25 - 559.9 1 2 0 -0.0002 12 0 0 0 1.66E+07 1.14E+07 - - - 3.2062 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.19744.19744.3 0.00464 Sep-36 K.LTLLTLHFPR.L "sp|Q92889|XPF_HUMAN,tr|A0A804HKF9|A0A804HKF9_HUMAN" 2 1209.7234 1.92 42951 19744 3 1209.723817 404.2484 DNA repair endonuclease XPF OS=Homo sapiens OX=9606 GN=ERCC4 PE=1 SV=3 9.76 3716.3 - 224995 - - - 0.3621 - 1.777 0.3 - 88.3 1 2 0 0.0004 10 0 0 0 2.23E+06 1.16E+06 - - - 3.5636 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19748.19748.2 0.00144 14-Sep K.IPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1059.5502 1.22 42953 19748 2 1059.551215 530.7824 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3716.7 - 2.07E+08 - - - 0.991 - 1.829 0.455 - 482.3 1 2 0 0.001 8 0 0 0 5.16E+09 4.24E+09 - - - 4.2222 0.9501 230117_WJC_METTL3_WT_vs_EV_F05.19749.19749.2 0.0667 12-Sep L.PDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 946.4661 1.29 42954 19749 2 946.468204 474.2403 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 6.27 3716.8 - 1.65E+06 - - - 2.2219 - 1.814 0.294 - 319.2 1 1 0 0.0021 7 0 0 0 3.52E+07 2.72E+07 - - - 3.0988 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19753.19753.2 0.00133 20-Nov K.ALLLSSVLSEK.G "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1158.686 3.7 42956 19753 2 1158.686839 580.3503 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 6.05 3717.4 - 378450 - - - 0.7327 - 2.324 0.377 - 346 1 2 0 0.0008 11 0 0 0 8.89E+06 2.40E+06 - - - 4.1066 0.9045 230117_WJC_METTL3_WT_vs_EV_F05.19757.19757.2 0.0484 18-Jul G.MEELIPLVNK.L sp|P50570|DYN2_HUMAN 1 1184.6475 1.31 42960 19757 2 1184.648836 593.331 Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2 4.53 3717.9 - 424239 - - - 1.1311 - 1.467 0.27 - 152.3 1 1 0 0.0013 10 0 0 0 6.27E+06 4.77E+06 - - - 2.1045 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19758.19758.2 0.000894 20-Sep K.SFYGSTLFLC[160.03]R[166.11].R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1359.6521 1.51 42961 19758 2 1359.654345 680.8333 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 7.94 3718 - 402626 - - - 1.6673 - 1.726 0.409 - 270.7 1 2 0 0.0023 11 0 0 0 6.98E+06 4.62E+06 - - - 3.5377 0.9963 230117_WJC_METTL3_WT_vs_EV_F05.19759.19759.2 0.0209 13/22 K.LANILFTQELAR[166.11].R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1397.7906 1.46 42962 19759 2 1397.786181 699.9026 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3718.1 - 353966 - - - -3.1757 - 2.577 0.309 - 758.4 1 2 0 -0.0044 12 0 0 0 1.66E+07 1.14E+07 - - - 3.8126 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.19761.19761.2 0.0218 14-Sep R.MGLLAVLR.S "sp|O95394|AGM1_HUMAN,tr|D6RF77|D6RF77_HUMAN,tr|D6RC77|D6RC77_HUMAN,tr|D6RCQ8|D6RCQ8_HUMAN,tr|A0A494C099|A0A494C099_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C163|A0A494C163_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|D6RCD1|D6RCD1_HUMAN" 9 871.5313 2.02 42964 19761 2 871.534723 436.7729 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 9.5 3718.4 - 289793 - - - 3.8771 - 1.861 0.398 - 298.9 1 2 0 0.0034 8 0 0 0 3.94E+06 1.95E+06 - - - 3.8528 0.9735 230117_WJC_METTL3_WT_vs_EV_F05.19768.19768.2 0.981 14-Sep R.NIPMLFVR[166.11].G sp|P62310|LSM3_HUMAN 1 998.5611 1.81 42969 19768 2 998.567103 500.2878 U6 snRNA-associated Sm-like protein LSm3 OS=Homo sapiens OX=9606 GN=LSM3 PE=1 SV=2 9.75 3719.2 - 592620 - - - 6.0337 - 1.315 0.256 - 308.6 1 2 0 0.006 8 0 0 0 4.33E+07 2.40E+07 - - - 1.7558 1 230117_WJC_METTL3_WT_vs_EV_F05.19769.19769.2 6.41E-07 20-Nov K.SFYGSTLFLC[160.03]R.R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1349.6438 1.51 42970 19769 2 1349.638942 675.8292 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 7.94 3719.4 - 516997 - - - -3.6054 - 2.188 0.57 - 409.3 1 2 0 -0.0049 11 0 0 0 6.98E+06 4.62E+06 - - - 5.3677 0.9363 230117_WJC_METTL3_WT_vs_EV_F05.19770.19770.2 2.17 18-Jul R.FPPVVFYTPK.E "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1193.6485 2.11 42971 19770 2 1193.652021 597.8315 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3719.5 - 261999 - - - 2.9649 - 1.243 0.013 - 70.6 2 2 0 0.0035 10 0 0 0 8.87E+06 4.21E+06 - - - -0.3914 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19774.19774.2 0.000115 18-Oct K.GIYLWDVEGR[166.11].K sp|P04181|OAT_HUMAN 1 1216.6116 1.17 42973 19774 2 1216.61255 609.3131 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.37 3720 - 556834 - - - 0.7866 - 1.99 0.456 - 348.6 1 2 0 0.001 10 0 0 0 5.01E+06 4.29E+06 - - - 4.3295 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19775.19775.2 0.00142 18-Oct K.ELLGQGLLLR.S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1110.6761 0.83 42974 19775 2 1110.67689 556.3453 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3720.1 - 2.71E+07 - - - 0.7167 - 2.07 0.351 - 378.6 1 2 0 0.0008 10 0 0 0 9.74E+07 1.17E+08 - - - 3.664 1 230117_WJC_METTL3_WT_vs_EV_F05.19776.19776.3 3.48E-08 20/60 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 240.42 42975 19776 3 1787.006073 596.6753 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3720.1 - 6.85E+06 - - - 1.1433 - 3.85 0.611 - 671.1 1 2 0 0.002 16 0 0 0 9.75E+07 4.05E+05 - - - 8.8105 1 230117_WJC_METTL3_WT_vs_EV_F05.19778.19778.2 1.98E-10 22/30 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 999 42977 19778 2 1787.004589 894.5093 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3720.4 - 1.79E+06 - - - 0.3128 - 3.969 0.599 - 1636.6 1 2 0 0.0006 16 0 0 0 2.07E+07 0.00E+00 - - - 6.8542 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19779.19779.2 0.0196 18-Sep K.QLEDILVLAK[136.11].Q "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A0A6YYJ5|A0A0A6YYJ5_HUMAN" 8 1148.6896 9.49 42978 19779 2 1148.689027 575.3521 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.37 3720.5 - 1.24E+06 - - - -0.5206 - 1.749 0.401 - 193.8 1 2 0 -0.0006 10 0 0 0 2.54E+07 2.68E+06 - - - 3.5631 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.19780.19780.2 0.563 20-Sep K.ALLLSSVLSEK[136.11].G "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1166.7002 3.7 42979 19780 2 1166.702859 584.3574 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 6.05 3720.7 - 1.12E+06 - - - 2.2876 - 2.085 0.206 - 162.9 1 2 0 0.0027 11 0 0 0 8.89E+06 2.40E+06 - - - 2.5494 0.995 230117_WJC_METTL3_WT_vs_EV_F05.19782.19782.2 0.0633 18-Aug K.NIFSVPEIVR.E "sp|O60645|EXOC3_HUMAN,tr|D6RB59|D6RB59_HUMAN" 2 1172.6554 2.55 42981 19782 2 1172.655533 587.335 Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3 6 3720.9 - 803359 - - - 0.1484 - 1.553 0.128 - 180.1 1 2 0 0.0002 10 0 0 0 7.25E+06 2.85E+06 - - - 1.2151 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19796.19796.2 5.48E-08 15/24 R.GAAGALLVYDITR[166.11].R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1328.7328 1.18 42993 19796 2 1328.734352 665.3737 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3722.8 - 901539 - - - 1.1899 - 3.425 0.189 - 1070 1 2 0 0.0016 13 0 0 0 6.81E+07 5.75E+07 - - - 3.5961 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19797.19797.2 0.000236 18-Oct K.GIYLWDVEGR.K sp|P04181|OAT_HUMAN 1 1206.6033 1.17 42994 19797 2 1206.603647 604.3089 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.37 3722.9 - 316941 - - - 0.2685 - 1.962 0.474 - 348.2 1 2 0 0.0003 10 0 0 0 5.01E+06 4.29E+06 - - - 4.4231 0.887 230117_WJC_METTL3_WT_vs_EV_F05.19798.19798.2 0.0558 18-Aug K.SVLIGEFLEK[136.11].V "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1141.6474 0.85 42995 19798 2 1141.639803 571.831 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 3723 - 355751 - - - -6.6772 - 1.696 0.212 - 168.5 1 2 0 -0.0076 10 0 0 0 1.12E+08 1.32E+08 - - - 2.079 1 230117_WJC_METTL3_WT_vs_EV_F05.19799.19799.2 1.08E-05 22-Nov K.IDVLQAEVAALK[136.11].T "sp|Q96QF0|RAB3I_HUMAN,tr|H0YI02|H0YI02_HUMAN,tr|J3KPG1|J3KPG1_HUMAN" 3 1276.7482 2.01 42996 19799 2 1276.752552 639.3814 Rab-3A-interacting protein OS=Homo sapiens OX=9606 GN=RAB3IP PE=1 SV=1 4.37 3723.1 - 227630 - - - 3.4063 - 2.269 0.469 - 457.3 1 2 0 0.0043 12 0 0 0 5.12E+06 2.55E+06 - - - 4.6595 1 230117_WJC_METTL3_WT_vs_EV_F05.19800.19800.2 4.15E-07 14/22 K.IYDALDVSLIER.G sp|P54136|SYRC_HUMAN 1 1405.7453 1.5 42997 19800 2 1405.745517 703.8799 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.03 3723.2 - 226557 - - - 0.1572 - 2.807 0.586 - 903.6 1 2 0 0.0002 12 0 0 0 9.85E+06 6.57E+06 - - - 6.0848 1 230117_WJC_METTL3_WT_vs_EV_F05.19801.19801.2 0.000393 22-Nov K.IYDALDVSLIER[166.11].G sp|P54136|SYRC_HUMAN 1 1415.7536 1.5 42998 19801 2 1415.754203 708.8841 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.03 3723.4 - 200727 - - - 0.4499 - 2.567 0.492 - 448.2 1 2 0 0.0006 12 0 0 0 9.85E+06 6.57E+06 - - - 5.1552 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19806.19806.2 0.000297 22-Oct K.YLGPAVLMQAYR.W sp|P21912|SDHB_HUMAN 1 1380.7224 6.69 43001 19806 2 1380.723546 691.3685 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 8.59 3723.9 - 454382 - - - 0.8358 - 1.883 0.387 - 267.8 1 2 0 0.0012 12 0 0 0 5.47E+06 8.16E+05 - - - 3.5642 0.9494 230117_WJC_METTL3_WT_vs_EV_F05.19807.19807.2 0.000103 22-Oct K.PYRPWGTEIGAF.- "sp|Q9Y5J3|HEY1_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 4 1392.6826 2.88 43002 19807 2 1392.684778 697.3486 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 6.43 3724.1 - 898777 - - - 1.538 - 1.93 0.281 - 272.2 1 1 0 0.0021 12 0 0 0 7.07E+06 2.46E+06 - - - 2.8458 0.9925 230117_WJC_METTL3_WT_vs_EV_F05.19808.19808.2 0.063 12-Jul R.WLSQYID.- "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 923.4389 - 43003 19808 2 923.438696 462.7267 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.3 3724.2 - 501036 - - - -0.2025 - 1.087 0.236 - 109.6 1 2 0 -0.0002 7 0 0 0 - - - - - 1.0484 0.9372 230117_WJC_METTL3_WT_vs_EV_F05.19810.19810.2 4.48 12-Jun K.DITSLFR.H "sp|Q99570|PI3R4_HUMAN,tr|D6RBB7|D6RBB7_HUMAN,tr|D6RJ98|D6RJ98_HUMAN,tr|D6RAC3|D6RAC3_HUMAN" 4 850.4549 2.03 43005 19810 2 850.455132 426.2347 Phosphoinositide 3-kinase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PIK3R4 PE=1 SV=3 5.84 3724.5 - 70315.8 - - - 0.3104 - 1.12 0 - 89.3 1 2 0 0.0003 7 0 0 0 4.22E+06 2.08E+06 - - - -0.6 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19813.19813.2 0.000201 14/20 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 135.99 43006 19813 2 1276.70214 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3724.9 - 2.73E+06 - - - -0.441 - 2.753 0.374 - 948.1 1 2 0 -0.0006 11 0 0 0 3.32E+08 2.44E+06 - - - 4.5428 1 230117_WJC_METTL3_WT_vs_EV_F05.19815.19815.2 0.00516 16-Nov R.ILDTLGLLR.Q "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN,tr|A0A087WWF4|A0A087WWF4_HUMAN" 3 1012.6281 1.07 43008 19815 2 1012.630143 507.3213 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 5.84 3725.1 - 2.20E+06 - - - 2.0363 - 2.404 0.444 - 335.5 1 2 0 0.0021 9 0 0 0 8.01E+06 7.48E+06 - - - 4.8573 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.19818.19818.2 0.624 18-Oct R.NVEELVIVLK.K "sp|P53618|COPB_HUMAN,tr|E9PP73|E9PP73_HUMAN" 2 1154.6911 2.88 43011 19818 2 1154.693245 578.3528 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 4.53 3725.5 - 976594 - - - 1.8793 - 1.702 0.128 - 185.6 1 2 0 0.0022 10 0 0 0 4.39E+06 1.53E+06 - - - 1.4702 1 230117_WJC_METTL3_WT_vs_EV_F05.19819.19819.2 0.00191 14/24 R.LLLFSSATDAAIR.V "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1376.7664 0.35 43012 19819 2 1376.767293 689.3905 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.84 3725.6 - 970526 - - - 0.6733 - 2.687 0.513 - 685 1 2 0 0.0009 13 0 0 0 3.34E+06 9.51E+06 - - - 5.3665 0.9669 230117_WJC_METTL3_WT_vs_EV_F05.19821.19821.2 4.07 12-May K.LLDDLFR[166.11].K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 900.4944 1.02 43014 19821 2 900.494608 451.2545 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3725.9 - 819836 - - - 0.1888 - 1.165 0.045 - 65.2 1 2 0 0.0002 7 0 0 0 1.41E+08 1.38E+08 - - - -0.1428 1 230117_WJC_METTL3_WT_vs_EV_F05.19822.19822.2 8.09E-10 15/26 K.FYGPAGPYGIFAGR.D sp|O15173|PGRC2_HUMAN 1 1471.7248 1.48 43015 19822 2 1471.726664 736.8697 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3726 - 530223 - - - 1.2428 - 2.546 0.583 - 837.7 1 2 0 0.0018 14 0 0 0 2.52E+07 1.70E+07 - - - 5.6916 1 230117_WJC_METTL3_WT_vs_EV_F05.19823.19823.2 6.72E-05 18-Nov R.LNDYIFSFDK.M sp|P54136|SYRC_HUMAN 1 1260.6027 1.77 43016 19823 2 1260.59931 631.3086 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.21 3726.2 - 521337 - - - -2.6527 - 2.452 0.474 - 688.9 1 2 0 -0.0033 10 0 0 0 3.34E+06 1.89E+06 - - - 5.0444 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.19825.19825.2 7.64E-05 18-Oct R.NVEELVIVLK[136.11].K "sp|P53618|COPB_HUMAN,tr|E9PP73|E9PP73_HUMAN" 2 1162.7053 2.88 43018 19825 2 1162.708601 582.3599 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 4.53 3726.4 - 455062 - - - 2.8606 - 1.96 0.269 - 277.1 1 2 0 0.0033 10 0 0 0 4.39E+06 1.53E+06 - - - 2.9052 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.19827.19827.2 0.048 14-Jun K.LDGFPLLR.R "sp|P09661|RU2A_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 2 929.5335 1.18 43020 19827 2 929.533307 465.774 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 5.84 3726.7 - 439739 - - - -0.156 - 1.583 0.216 - 75.6 1 2 0 -0.0001 8 0 0 0 1.50E+06 1.26E+06 - - - 2.0216 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19829.19829.2 0.00119 24-Nov R.LVDIIAAVPPQYR.K "sp|Q9H9T3|ELP3_HUMAN,tr|E5RIZ7|E5RIZ7_HUMAN,tr|E5RIC0|E5RIC0_HUMAN,tr|E5RHY2|E5RHY2_HUMAN,tr|E5RHR2|E5RHR2_HUMAN" 5 1453.8293 1.98 43022 19829 2 1453.830633 727.9219 Elongator complex protein 3 OS=Homo sapiens OX=9606 GN=ELP3 PE=1 SV=2 5.84 3726.9 - 409775 - - - 0.9169 - 2.458 0.406 - 435.4 1 2 0 0.0013 13 0 0 0 2.87E+06 1.45E+06 - - - 4.3475 1 230117_WJC_METTL3_WT_vs_EV_F05.19830.19830.2 1.98E-09 26-Dec K.FYGPAGPYGIFAGR[166.11].D sp|O15173|PGRC2_HUMAN 1 1481.7331 1.48 43023 19830 2 1481.73072 741.8738 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3727.1 - 367991 - - - -1.6096 - 2.382 0.627 - 490.4 1 2 0 -0.0024 14 0 0 0 2.52E+07 1.70E+07 - - - 5.8493 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.19831.19831.2 0.0048 14-Jun K.LDGFPLLR[166.11].R "sp|P09661|RU2A_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 2 939.5417 1.18 43024 19831 2 939.542139 470.7781 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 5.84 3727.2 - 308080 - - - 0.4438 - 1.516 0.322 - 88.9 1 2 0 0.0004 8 0 0 0 1.50E+06 1.26E+06 - - - 2.674 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.19839.19839.2 0.0159 14-Jul R.DWVLNEFK.H "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1049.5182 1.28 43031 19839 2 1049.518449 525.7664 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3728 - 337707 - - - 0.2411 - 1.43 0.332 - 213.3 1 2 0 0.0003 8 0 0 0 8.03E+07 6.26E+07 - - - 2.5718 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.19840.19840.2 0.00072 14-Sep R.IWYLLDGK.M "sp|Q9BYD1|RM13_HUMAN,tr|E5RFI2|E5RFI2_HUMAN" 2 1006.5488 1.14 43032 19840 2 1006.548809 504.2817 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 5.83 3728.1 - 199554 - - - 0.0407 - 1.863 0.185 - 311.5 1 2 0 0 8 0 0 0 1.38E+07 1.20E+07 - - - 2.2839 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.19841.19841.2 0.000182 24-Oct K.LDNLLLDTEGYVK.L "sp|Q16512|PKN1_HUMAN,tr|K7EL10|K7EL10_HUMAN" 2 1491.7821 -1 43033 19841 2 1491.790214 746.8983 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 4.03 3728.2 - 0 - - - 5.4559 - 2.305 0.433 - 345.9 1 2 0 0.0081 13 0 0 0 0.00E+00 0.00E+00 - - - 4.3798 0.9919 230117_WJC_METTL3_WT_vs_EV_F05.19842.19842.2 0.000772 20-Nov R.WLDDIGLPQYK.T "sp|Q86W92|LIPB1_HUMAN,sp|Q8ND30|LIPB2_HUMAN,tr|A0A804HJY3|A0A804HJY3_HUMAN,tr|A0A804HKA2|A0A804HKA2_HUMAN,tr|E9PP16|E9PP16_HUMAN,tr|F5GZP6|F5GZP6_HUMAN" 6 1346.6871 1.21 43034 19842 2 1346.696693 674.3508 Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2 4.21 3728.4 - 0 - - - 7.1583 - 2.085 0.434 - 184.7 1 2 0 0.0096 11 0 0 0 1.29E+06 1.06E+06 - - - 4.2312 1 230117_WJC_METTL3_WT_vs_EV_F05.19846.19846.2 1.16E-05 20-Nov K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 8.11 43036 19846 2 1184.713887 593.3637 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3728.8 - 7.47E+06 - - - 0.8559 - 2.523 0.573 - 492 1 2 0 0.001 11 0 0 0 1.48E+09 1.83E+08 - - - 5.7764 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19847.19847.2 0.00567 18-Oct R.AAFVLPEFAR.K "sp|P19623|SPEE_HUMAN,tr|K7EL89|K7EL89_HUMAN" 2 1119.6077 5.68 43037 19847 2 1119.60829 560.8111 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 6.05 3728.8 - 3.72E+06 - - - 0.5448 - 1.941 0.404 - 271.1 1 2 0 0.0006 10 0 0 0 6.09E+07 1.07E+07 - - - 3.876 0.9893 230117_WJC_METTL3_WT_vs_EV_F05.19848.19848.2 3.21 12-Jun K.LLDDLFR.K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 890.4862 1.02 43038 19848 2 890.486542 446.2504 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3728.9 - 6.17E+06 - - - 0.42 - 1.226 0.118 - 112.3 1 2 0 0.0004 7 0 0 0 1.41E+08 1.38E+08 - - - 0.558 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.19849.19849.2 0.0263 14-Jun R.NLIEWLNK[136.11].Y sp|Q96DG6|CMBL_HUMAN 1 1036.5797 0.85 43039 19849 2 1036.580304 519.2971 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 6 3728.9 - 2.77E+06 - - - 0.601 - 1.32 0.32 - 131.3 1 2 0 0.0006 8 0 0 0 6.30E+07 7.39E+07 - - - 2.2416 1 230117_WJC_METTL3_WT_vs_EV_F05.19850.19850.2 3.17E-05 16-Nov K.YDWDLLAAR[166.11].S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1131.5588 1.69 43040 19850 2 1131.559666 566.7867 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3729 - 1.77E+06 - - - 0.7397 - 2.059 0.532 - 478.3 1 2 0 0.0008 9 0 0 0 6.82E+07 4.03E+07 - - - 5.0595 0.9962 230117_WJC_METTL3_WT_vs_EV_F05.19851.19851.2 0.0302 14-Jul R.SLPVFPFR.E "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 961.5385 1.73 43041 19851 2 961.537622 481.7765 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 9.47 3729.1 - 916773 - - - -0.9526 - 1.292 0.297 - 249.9 1 2 0 -0.0009 8 0 0 0 6.98E+06 4.02E+06 - - - 2.007 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19852.19852.2 0.275 20-Oct -.MLLFVEQVASK.G "sp|Q71RC2|LARP4_HUMAN,tr|F8W1Z5|F8W1Z5_HUMAN" 2 1263.6897 0.36 43042 19852 2 1263.690602 632.8521 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 5.75 3729.2 - 805551 - - - 0.7177 - 2.047 0.336 - 288.9 1 2 0 0.0009 11 0 0 0 1.25E+07 3.46E+07 - - - 3.4604 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.19854.19854.3 0.182 Aug-40 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 1.46 43044 19854 3 1276.703217 426.5748 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3729.3 - 631535 - - - 0.4026 - 1.794 0.231 - 116.5 1 2 0 0.0005 11 0 0 0 2.02E+06 1.39E+06 - - - 2.7756 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19855.19855.2 0.272 16-Sep K.DGLLGAELR.L sp|P43026|GDF5_HUMAN 1 942.5134 7.34 43045 19855 2 942.51498 472.264 Growth\differentiation factor 5 OS=Homo sapiens OX=9606 GN=GDF5 PE=1 SV=3 4.37 3729.5 - 630562 - - - 1.6286 - 1.904 0.228 - 216 1 2 0 0.0015 9 0 0 0 9.76E+06 1.33E+06 - - - 2.5875 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19857.19857.2 1.02E-06 13/24 R.AGLNGLQLAVLAR.L sp|Q96S55|WRIP1_HUMAN 1 1294.7721 5.31 43047 19857 2 1294.773363 648.3933 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 9.79 3729.6 - 469706 - - - 0.96 - 2.743 0.223 - 734 1 2 0 0.0012 13 0 0 0 3.68E+06 6.94E+05 - - - 3.2774 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.19859.19859.2 0.00668 14-Sep K.IPDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1069.5584 1.22 43048 19859 2 1069.559124 535.7865 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3729.8 - 3.49E+07 - - - 0.6442 - 1.846 0.449 - 467.3 1 2 0 0.0007 8 0 0 0 5.16E+09 4.24E+09 - - - 4.2059 1 230117_WJC_METTL3_WT_vs_EV_F05.19861.19861.2 4.91E-06 20-Nov K.TAVETAVLLLR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1194.7211 8.11 43049 19861 2 1194.722115 598.3678 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3730 - 1.35E+06 - - - 0.8136 - 2.375 0.579 - 428.4 1 2 0 0.001 11 0 0 0 1.48E+09 1.83E+08 - - - 5.6572 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.19862.19862.2 0.0639 16-Oct K.YLGLLENLR[166.11].V "sp|O00159|MYO1C_HUMAN,tr|F5H6E2|F5H6E2_HUMAN" 2 1099.6265 1.27 43050 19862 2 1099.626422 550.8205 Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4 6 3730.1 - 638163 - - - -0.0846 - 1.566 0.353 - 328 1 2 0 -0.0001 9 0 0 0 5.88E+06 4.64E+06 - - - 2.9458 1 230117_WJC_METTL3_WT_vs_EV_F05.19863.19863.2 1.20E-05 16-Sep K.YDWDLLAAR.S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1121.5506 1.67 43051 19863 2 1121.550954 561.7826 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3730.1 - 2.41E+06 - - - 0.3522 - 1.927 0.548 - 377.4 1 2 0 0.0004 9 0 0 0 6.87E+07 4.11E+07 - - - 4.9861 1 230117_WJC_METTL3_WT_vs_EV_F05.19865.19865.2 2.87E-05 18-Nov R.QEVVDLLLAR[166.11].G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1164.6742 1.31 43053 19865 2 1164.670755 583.3444 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3730.3 - 341106 - - - -2.9519 - 2.323 0.509 - 610.3 1 2 0 -0.0034 10 0 0 0 5.55E+07 4.23E+07 - - - 5.1521 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.19869.19869.3 0.00044 14/40 K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 8.1 43057 19869 3 1184.712664 395.9116 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3730.8 - 203710 - - - -0.1764 - 2.538 0.405 - 285.9 1 2 0 -0.0002 11 0 0 0 3.71E+07 4.59E+06 - - - 5.7012 0.9479 230117_WJC_METTL3_WT_vs_EV_F05.19870.19870.2 0.532 14-Jun R.SLPVFPFR[166.11].E "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 971.5468 1.73 43058 19870 2 971.544341 486.7807 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 9.47 3731 - 195789 - - - -2.5392 - 1.211 0.143 - 123.6 1 2 0 -0.0025 8 0 0 0 6.98E+06 4.02E+06 - - - 0.6738 0.999 230117_WJC_METTL3_WT_vs_EV_F05.19874.19874.2 0.36 18-Jul K.IINFAPSLLR.L "sp|O15397|IPO8_HUMAN,tr|F5H2I3|F5H2I3_HUMAN" 2 1142.6812 1.6 43061 19874 2 1142.683545 572.3479 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 9.75 3731.5 - 574981 - - - 2.0706 - 1.693 0.277 - 139.8 1 2 0 0.0024 10 0 0 0 2.59E+07 1.62E+07 - - - 2.5558 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.19877.19877.2 0.0142 12-Jun K.NMFAIWR.V "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 936.464 1.03 43063 19877 2 936.466071 469.2393 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3731.8 - 1.05E+06 - - - 2.219 - 1.316 0.314 - 214.2 1 2 0 0.0021 7 0 0 0 3.65E+07 3.56E+07 - - - 2.2296 1 230117_WJC_METTL3_WT_vs_EV_F05.19878.19878.2 5.27E-05 18-Dec R.QEVVDLLLAR.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1154.6659 1.31 43064 19878 2 1154.667353 578.3402 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3731.9 - 5.42E+06 - - - 1.2385 - 2.56 0.487 - 839.5 1 2 0 0.0014 10 0 0 0 5.55E+07 4.23E+07 - - - 5.2614 1 230117_WJC_METTL3_WT_vs_EV_F05.19880.19880.2 6.97E-05 13/20 K.FDGILGMAYPR.L "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1238.6118 8.1 43066 19880 2 1238.610518 620.3132 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.84 3732.2 - 1.89E+06 - - - -1.0181 - 2.39 0.434 - 767.6 1 2 0 -0.0013 11 0 0 0 1.58E+07 1.95E+06 - - - 4.6032 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.19882.19882.2 0.0249 16-Sep K.YLGLLENLR.V "sp|O00159|MYO1C_HUMAN,tr|F5H6E2|F5H6E2_HUMAN" 2 1089.6182 0.64 43068 19882 2 1089.620587 545.8164 Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4 6 3732.4 - 1.33E+06 - - - 2.1494 - 1.798 0.347 - 233 1 2 0 0.0023 9 0 0 0 3.39E+06 5.30E+06 - - - 3.3005 0.9269 230117_WJC_METTL3_WT_vs_EV_F05.19885.19885.2 0.00139 22-Oct K.LLQVASPFLEPH.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1349.7343 - 43071 19885 2 1349.737708 675.8744 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 5.24 3732.8 - 759630 - - - 2.4975 - 1.547 0.347 - 108.3 1 1 0 0.0034 12 0 0 0 - - - - - 2.7509 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.19886.19886.2 0.0474 14-Aug R.LIFLDSIK[136.11].S "sp|Q99996|AKAP9_HUMAN,tr|A0A0A0MRF6|A0A0A0MRF6_HUMAN,tr|A0A7P0TBH8|A0A7P0TBH8_HUMAN,tr|A0A7P0TAX3|A0A7P0TAX3_HUMAN,tr|A0A7P0T9A9|A0A7P0T9A9_HUMAN,tr|A0A7P0T8N5|A0A7P0T8N5_HUMAN,tr|A0A7P0TBI4|A0A7P0TBI4_HUMAN,tr|A0A7P0Z4Q5|A0A7P0Z4Q5_HUMAN,tr|A0A7P0Z4N5|A0A7P0Z4N5_HUMAN,tr|A0A7P0TAD6|A0A7P0TAD6_HUMAN,tr|A0A7P0T939|A0A7P0T939_HUMAN,tr|A0A7P0T928|A0A7P0T928_HUMAN,tr|A0A7P0TAA2|A0A7P0TAA2_HUMAN" 13 955.5834 1.4 43072 19886 2 955.586029 478.799 A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4 5.84 3732.9 - 681349 - - - 2.7836 - 1.453 0.304 - 135.2 1 2 0 0.0027 8 0 0 0 3.50E+06 2.50E+06 - - - 2.4124 1 230117_WJC_METTL3_WT_vs_EV_F05.19890.19890.2 2.02E-06 13/24 R.VETPVLPPVLVPR.H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1414.8548 1.92 43076 19890 2 1414.853789 708.4347 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3733.5 - 381222 - - - -0.7054 - 2.299 0.583 - 333.8 1 2 0 -0.001 13 0 0 0 1.08E+07 5.60E+06 - - - 5.4833 0.8458 230117_WJC_METTL3_WT_vs_EV_F05.19894.19894.2 0.0025 16-Jul R.GFFGFPGPR.S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 980.4868 1.85 43080 19894 2 981.489396 491.2507 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3734 - 109397 - - - 1022.5114 - 1.512 0.36 - 124.2 1 2 0 1.0026 9 0 0 0 3.34E+07 1.81E+07 - - - 2.5812 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.19901.19901.3 0.0246 Dec-40 K.TAVETAVLLLR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1194.7211 8.24 43085 19901 3 1194.721948 399.2477 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3734.8 - 163806 - - - 0.6738 - 2.173 0.398 - 207.8 1 2 0 0.0008 11 0 0 0 3.71E+07 4.51E+06 - - - 5.1819 0.9892 230117_WJC_METTL3_WT_vs_EV_F05.19905.19905.2 2.77 12-Jul R.VTLLLFK.D "sp|Q9Y3C4|TPRKB_HUMAN,sp|Q86YN1|DOPP1_HUMAN,tr|H7C1Z8|H7C1Z8_HUMAN,tr|H7BXT6|H7BXT6_HUMAN" 4 832.5422 1.94 43089 19905 2 832.542681 417.2784 EKC\KEOPS complex subunit TPRKB OS=Homo sapiens OX=9606 GN=TPRKB PE=1 SV=1 8.72 3735.2 - 0 - - - 0.5465 - 1.496 0.056 - 188.9 3 2 0 0.0005 7 0 0 0 3.02E+06 1.56E+06 - - - 0.5176 0.998 230117_WJC_METTL3_WT_vs_EV_F05.19911.19911.2 0.026 20-Jun R.YLLQPLGDFSR.A "sp|Q7Z3U7|MON2_HUMAN,tr|A0A286YFF8|A0A286YFF8_HUMAN" 2 1307.6874 0.24 43095 19911 2 1307.689739 654.851 Protein MON2 homolog OS=Homo sapiens OX=9606 GN=MON2 PE=1 SV=3 5.84 3735.9 - 0 - - - 1.7986 - 1.511 0.216 - 84.6 1 2 0 0.0024 11 0 0 0 1.66E+06 6.85E+06 - - - 1.7523 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19912.19912.2 0.00251 28-Jul R.LTPSASLPPAQLLLR.A "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 1575.9348 1.64 43096 19912 2 1575.934779 788.9747 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 9.75 3736.1 - 0 - - - -0.0311 - 1.562 0.398 - 77.3 1 2 0 0 15 0 0 0 1.72E+06 1.05E+06 - - - 3.077 0.999 230117_WJC_METTL3_WT_vs_EV_F05.19916.19916.2 0.0519 16-Jul R.LVLDPYLLK.Y "sp|Q9Y2R5|RT17_HUMAN,tr|I3L0E3|I3L0E3_HUMAN,tr|E9PE17|E9PE17_HUMAN" 3 1072.6532 0.9 43099 19916 2 1072.654893 537.3339 "28S ribosomal protein S17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS17 PE=1 SV=1" 5.83 3736.6 - 1.12E+07 - - - 1.5476 - 1.444 0.317 - 131.9 1 2 0 0.0017 9 0 0 0 2.51E+07 2.78E+07 - - - 2.4448 1 230117_WJC_METTL3_WT_vs_EV_F05.19917.19917.3 6.61E-12 29/76 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 2.39 43100 19917 3 2197.089666 733.3694 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3736.7 - 3.41E+06 - - - 1.5521 - 5.324 0.643 - 1116.6 1 2 0 0.0034 20 0 0 0 7.22E+06 3.02E+06 - - - 9.7647 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19919.19919.2 0.00287 16-Aug K.SLTYLSILR.N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 3 1064.623 1.11 43102 19919 2 1064.625165 533.3188 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 8.46 3737 - 3.06E+06 - - - 2.0373 - 1.681 0.402 - 234.5 1 2 0 0.0022 9 0 0 0 1.29E+07 1.16E+07 - - - 3.5121 0.9514 230117_WJC_METTL3_WT_vs_EV_F05.19920.19920.2 0.00242 20-Nov K.FEQLVSIGSSY.N sp|Q9NXV2|KCTD5_HUMAN 1 1228.5976 - 43103 19920 2 1228.597018 615.3061 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4 3737.1 - 3.05E+06 - - - -0.4485 - 1.662 0.469 - 469.4 1 1 0 -0.0006 11 0 0 0 - - - - - 3.8792 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.19922.19922.2 0.0147 20-Oct R.IAIQGIITAIK.Y sp|Q6NSI4|RADX_HUMAN 1 1139.7278 2.17 43105 19922 2 1139.728025 570.8712 RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2 8.75 3737.4 - 1.79E+06 - - - 0.2018 - 1.994 0.396 - 189.3 1 2 0 0.0002 11 0 0 0 4.19E+06 1.93E+06 - - - 3.8328 1 230117_WJC_METTL3_WT_vs_EV_F05.19923.19923.2 8.10E-06 18-Sep R.LWGDIYFNPK.T sp|Q15029|U5S1_HUMAN 1 1251.6288 1.04 43106 19923 2 1251.629581 626.8217 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.83 3737.5 - 1.70E+06 - - - 0.6168 - 2.042 0.529 - 287.7 1 2 0 0.0008 10 0 0 0 9.27E+06 8.89E+06 - - - 4.9407 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19927.19927.2 0.00115 16-Sep R.GFFGFPGPR.S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 980.4868 1.85 43110 19927 2 980.487334 491.2507 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3738 - 829732 - - - 0.5069 - 1.727 0.426 - 242.9 1 2 0 0.0005 9 0 0 0 3.34E+07 1.81E+07 - - - 3.768 0.9705 230117_WJC_METTL3_WT_vs_EV_F05.19929.19929.2 0.157 20-Nov R.VALDSLVLQMK.S sp|Q14147|DHX34_HUMAN 1 1215.6897 4.75 43112 19929 2 1215.700496 608.8521 Probable ATP-dependent RNA helicase DHX34 OS=Homo sapiens OX=9606 GN=DHX34 PE=1 SV=2 5.81 3738.3 - 643820 - - - 8.8847 - 1.872 0.317 - 250.6 1 2 0 0.0108 11 0 0 0 1.02E+06 2.15E+05 - - - 3.0752 0.9947 230117_WJC_METTL3_WT_vs_EV_F05.19930.19930.2 1.79 12-Jun K.DFLLSLK[136.11].T sp|Q86UP2|KTN1_HUMAN 1 842.4993 1.09 43113 19930 2 842.500024 422.2569 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.84 3738.4 - 556044 - - - 0.8534 - 1.457 0.099 - 157 1 2 0 0.0007 7 0 0 0 2.09E+06 1.91E+06 - - - 0.9646 0.9013 230117_WJC_METTL3_WT_vs_EV_F05.19932.19932.2 0.0306 20-Nov R.YVDQVLQLVYK.D sp|P11717|MPRI_HUMAN 1 1366.7497 2.6 43115 19932 2 1366.740676 684.3821 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 5.83 3738.7 - 479070 - - - -6.5681 - 1.382 0.305 - 77.1 1 2 0 -0.009 11 0 0 0 1.88E+06 7.23E+05 - - - 2.1661 1 230117_WJC_METTL3_WT_vs_EV_F05.19938.19938.2 0.000206 18-Dec R.DAVLLVFANK[136.11].Q "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 5 1096.6372 1.93 43119 19938 2 1096.639068 549.3259 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 5.84 3739.3 - 3.38E+06 - - - 1.707 - 2.418 0.514 - 728.4 1 2 0 0.0019 10 0 0 0 1.02E+08 5.29E+07 - - - 5.3014 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.19940.19940.2 0.174 16-Sep R.NLLGLALGR.L sp|Q8N5L8|RP25L_HUMAN 1 925.5709 1.08 43121 19940 2 925.571208 463.7927 Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1 9.75 3739.4 - 2.32E+06 - - - 0.3317 - 1.68 0.125 - 306.8 1 2 0 0.0003 9 0 0 0 3.72E+07 3.43E+07 - - - 1.4651 1 230117_WJC_METTL3_WT_vs_EV_F05.19942.19942.2 1.04E-08 14/20 R.VFSWGFGGYGR[166.11].L sp|Q9P258|RCC2_HUMAN 1 1241.5857 1.63 43123 19942 2 1241.585771 621.8001 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 8.72 3739.6 - 1.20E+06 - - - 0.0467 - 2.518 0.484 - 652.1 1 2 0 0.0001 11 0 0 0 1.02E+07 6.24E+06 - - - 5.114 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.19944.19944.2 0.000196 16-Sep R.GFFGFPGPR[166.11].S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 990.4951 1.85 43125 19944 2 990.49561 496.2548 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3739.9 - 1.01E+06 - - - 0.5078 - 1.56 0.47 - 209.9 1 2 0 0.0005 9 0 0 0 3.34E+07 1.81E+07 - - - 3.7988 1 230117_WJC_METTL3_WT_vs_EV_F05.19946.19946.2 5.61E-11 14/22 K.LYDNLLEQNLIR.V sp|O00231|PSD11_HUMAN 1 1502.8093 1.77 43127 19946 2 1502.808639 752.4119 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3740.1 - 898398 - - - -0.4352 - 3.073 0.559 - 839.7 1 2 0 -0.0007 12 0 0 0 2.28E+07 1.29E+07 - - - 6.1235 1 230117_WJC_METTL3_WT_vs_EV_F05.19948.19948.2 8.62E-08 14/22 K.LYDNLLEQNLIR[166.11].V sp|O00231|PSD11_HUMAN 1 1512.8176 1.77 43129 19948 2 1512.817584 757.4161 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3740.3 - 534982 - - - 0.0139 - 3.057 0.587 - 771 1 2 0 0 12 0 0 0 2.28E+07 1.29E+07 - - - 6.3167 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19949.19949.2 0.00118 20-Dec K.IIADIFEYTAK.H sp|P22033|MUTA_HUMAN 1 1282.6809 1.94 43130 19949 2 1282.684197 642.3477 "Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4" 4.37 3740.4 - 424848 - - - 2.5665 - 1.879 0.313 - 428.1 1 2 0 0.0033 11 0 0 0 4.17E+06 2.15E+06 - - - 3.0581 1 230117_WJC_METTL3_WT_vs_EV_F05.19950.19950.2 2.93E-06 13/20 R.PMEVFMC[160.03]SVLK[136.11].R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1347.648 0.97 43131 19950 2 1347.650604 674.8313 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3740.6 - 422950 - - - 1.9048 - 2.569 0.534 - 619.2 1 1 0 0.0026 11 0 0 0 1.54E+07 1.59E+07 - - - 5.5368 0.9398 230117_WJC_METTL3_WT_vs_EV_F05.19954.19954.2 4.55 12-Jun K.DFLLSLK.T sp|Q86UP2|KTN1_HUMAN 1 834.4851 1.09 43135 19954 2 834.48531 418.2498 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.84 3741.1 - 241193 - - - 0.2457 - 1.095 0.016 - 130.5 1 2 0 0.0002 7 0 0 0 2.09E+06 1.91E+06 - - - -0.5533 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.19960.19960.2 0.136 16-Aug R.NLLGLALGR[166.11].L sp|Q8N5L8|RP25L_HUMAN 1 935.5792 1.09 43140 19960 2 935.579356 468.7969 Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1 9.75 3741.9 - 1.18E+07 - - - 0.1977 - 1.683 0.179 - 229.7 1 2 0 0.0002 9 0 0 0 3.75E+07 3.43E+07 - - - 1.8691 1 230117_WJC_METTL3_WT_vs_EV_F05.19961.19961.2 1.64E-10 13/20 R.PMEVFMC[160.03]SVLK.R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1339.6338 0.97 43141 19961 2 1339.633879 670.8242 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3741.9 - 5.52E+06 - - - 0.0314 - 2.725 0.672 - 685.4 1 1 0 0 11 0 0 0 1.54E+07 1.59E+07 - - - 6.7163 1 230117_WJC_METTL3_WT_vs_EV_F05.19962.19962.2 5.30E-06 20/30 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 7.91 43142 19962 2 1549.883934 775.9487 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3742 - 3.71E+06 - - - 0.7368 - 3.261 0.54 - 1295.1 1 2 0 0.0011 16 0 0 0 2.57E+08 3.25E+07 - - - 5.9352 1 230117_WJC_METTL3_WT_vs_EV_F05.19963.19963.2 0.00128 18/28 R.LPLPSPALEYTLGSR.L sp|Q8IU81|I2BP1_HUMAN 1 1612.8825 2.49 43143 19963 2 1612.882434 807.4485 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3742.1 - 3.34E+06 - - - -0.0149 - 2.964 0.461 - 940.2 1 2 0 0 15 0 0 0 2.83E+07 1.14E+07 - - - 5.1172 0.999 230117_WJC_METTL3_WT_vs_EV_F05.19965.19965.2 0.000255 28-Nov R.LPLPSPALEYTLGSR[166.11].L sp|Q8IU81|I2BP1_HUMAN 1 1622.8907 2.49 43145 19965 2 1622.888883 812.4526 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3742.2 - 4.98E+06 - - - -1.1369 - 1.637 0.484 - 174.8 1 2 0 -0.0018 15 0 0 0 2.83E+07 1.14E+07 - - - 3.827 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.19966.19966.3 0.0094 Nov-44 K.LYDNLLEQNLIR.V sp|O00231|PSD11_HUMAN 1 1502.8093 -1 43146 19966 3 1502.810644 501.9437 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3742.3 - 1.41E+06 - - - 0.899 - 2.281 0.184 - 254.8 1 2 0 0.0014 12 0 0 0 0.00E+00 0.00E+00 - - - 2.8768 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.19967.19967.2 0.066 16-Sep R.GSLITSLLR[166.11].S sp|Q53FA7|QORX_HUMAN 1 968.5894 1.06 43147 19967 2 968.59007 485.302 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3742.4 - 1.40E+06 - - - 0.6907 - 1.853 0.266 - 193.9 1 2 0 0.0007 9 0 0 0 3.51E+06 3.30E+06 - - - 2.7899 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.19968.19968.2 0.0315 12-Sep R.WIVNLIR.N "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 15 912.5545 0.89 43148 19968 2 912.554707 457.2845 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 9.75 3742.6 - 1.14E+06 - - - 0.2027 - 1.414 0.273 - 457.2 1 2 0 0.0002 7 0 0 0 2.44E+07 2.73E+07 - - - 2.155 1 230117_WJC_METTL3_WT_vs_EV_F05.19972.19972.2 8.36E-06 24-Oct R.VETPVLPPVLVPR[166.11].H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1424.8631 1.92 43152 19972 2 1424.863274 713.4388 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3743 - 782720 - - - 0.1523 - 2.062 0.503 - 211 1 2 0 0.0002 13 0 0 0 1.08E+07 5.60E+06 - - - 4.6134 1 230117_WJC_METTL3_WT_vs_EV_F05.19974.19974.2 5.23E-05 21/30 R.ALIAGGGAPEIELALR[166.11].L sp|P50991|TCPD_HUMAN 1 1559.8911 8.19 43154 19974 2 1559.894332 780.9528 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3743.3 - 611903 - - - 2.0963 - 3.194 0.438 - 1798.2 1 2 0 0.0033 16 0 0 0 2.55E+08 3.12E+07 - - - 5.1301 0.9632 230117_WJC_METTL3_WT_vs_EV_F05.19977.19977.3 0.643 Jul-40 R.TLVLLDNLNVR.E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1268.7452 -1 43157 19977 3 1268.745415 423.9224 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3743.6 - 431404 - - - 0.1411 - 1.545 0.094 - 83.9 1 2 0 0.0002 11 0 0 0 0.00E+00 0.00E+00 - - - 0.8238 0.999 230117_WJC_METTL3_WT_vs_EV_F05.19982.19982.2 0.0453 12-Aug R.WIVNLIR[166.11].N "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 15 922.5628 0.89 43161 19982 2 922.564342 462.2887 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 9.75 3744.1 - 8.86E+06 - - - 1.6801 - 1.452 0.294 - 383.6 1 2 0 0.0015 7 0 0 0 2.44E+07 2.73E+07 - - - 2.3937 1 230117_WJC_METTL3_WT_vs_EV_F05.19983.19983.2 0.000256 18-Oct K.YFSSMAEFLK.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1221.574 1.17 43162 19983 2 1221.577343 611.7943 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 3744.2 - 8.78E+06 - - - 2.7391 - 1.876 0.533 - 214.9 1 2 0 0.0033 10 0 0 0 3.24E+07 2.77E+07 - - - 4.7328 1 230117_WJC_METTL3_WT_vs_EV_F05.19985.19985.2 1.31E-06 18-Nov R.VFYYLVQDLK[136.11].C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1294.7053 0.93 43164 19985 2 1294.707921 648.3599 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3744.3 - 5.68E+06 - - - 2.0437 - 2.397 0.54 - 485.6 1 2 0 0.0026 10 0 0 0 5.01E+07 5.38E+07 - - - 5.4688 1 230117_WJC_METTL3_WT_vs_EV_F05.19988.19988.3 1.33E-10 22/60 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 6.61 43167 19988 3 1549.886744 517.6349 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3744.6 - 2.75E+06 - - - 2.5499 - 3.796 0.571 - 761.7 1 2 0 0.004 16 0 0 0 1.16E+07 1.76E+06 - - - 8.3277 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.19989.19989.2 3.04E-05 18-Oct R.YVEFNLLYDR.G "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1330.6558 1.46 43168 19989 2 1330.660411 666.3352 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.37 3744.7 - 1.60E+07 - - - 3.5013 - 1.901 0.458 - 263.8 1 2 0 0.0047 10 0 0 0 9.98E+06 6.83E+06 - - - 4.2154 1 230117_WJC_METTL3_WT_vs_EV_F05.19991.19991.2 5.05E-08 14/20 K.TYLQALPYFDR.L "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1385.698 -1 43170 19991 2 1385.697286 693.8563 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 5.5 3744.9 - 1.39E+06 - - - -0.4806 - 2.624 0.519 - 776.9 1 2 0 -0.0007 11 0 0 0 0.00E+00 0.00E+00 - - - 5.4839 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.19993.19993.2 0.229 16-Sep R.GSLITSLLR.S sp|Q53FA7|QORX_HUMAN 1 958.5811 1.06 43172 19993 2 958.583012 480.2978 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3745.2 - 1.16E+06 - - - 1.9623 - 1.723 0.216 - 188.9 1 2 0 0.0019 9 0 0 0 3.51E+06 3.30E+06 - - - 2.2098 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20001.20001.2 0.000199 20-Aug K.TVLELQYVLDK.L "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1319.7337 1.12 43179 20001 2 1319.736002 660.8741 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.37 3746.1 - 2.11E+06 - - - 1.7678 - 1.747 0.517 - 158.2 1 2 0 0.0023 11 0 0 0 1.61E+08 1.44E+08 - - - 4.3681 0.9943 230117_WJC_METTL3_WT_vs_EV_F05.20003.20003.2 0.016 14-Sep R.WLLSDYVK.V "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN,tr|C9JZH6|C9JZH6_HUMAN" 3 1022.5437 2.11 43181 20003 2 1022.541796 512.2791 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.83 3746.3 - 751417 - - - -1.8454 - 1.608 0.231 - 374.2 1 2 0 -0.0019 8 0 0 0 5.57E+06 2.64E+06 - - - 2.1791 1 230117_WJC_METTL3_WT_vs_EV_F05.20007.20007.2 0.000374 14/26 K.IPPPVIMVQNVSFK.Y sp|Q9UG63|ABCF2_HUMAN 1 1567.8796 4.11 43185 20007 2 1567.881472 784.9471 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.75 3746.8 - 473649 - - - 1.1806 - 2.424 0.479 - 513.9 1 2 0 0.0019 14 0 0 0 3.49E+06 8.50E+05 - - - 4.8002 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20008.20008.2 1.99E-05 20-Nov K.DSLTLVFVETK[136.11].K "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1258.69 0.03 43186 20008 2 1258.689622 630.3523 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3746.9 - 442206 - - - -0.3154 - 2.24 0.431 - 471.2 1 2 0 -0.0004 11 0 0 0 9.06E+04 2.83E+06 - - - 4.4059 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20016.20016.2 0.00455 16-Aug K.FFPLIEVNK.V "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1105.6172 0.85 43193 20016 2 1105.616717 553.8159 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6 3747.9 - 1.94E+06 - - - -0.4206 - 1.511 0.466 - 170.1 1 2 0 -0.0005 9 0 0 0 2.29E+08 2.71E+08 - - - 3.6769 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20021.20021.2 1.79E-05 16-Sep R.LTSFITVFK.Y "sp|Q13617|CUL2_HUMAN,tr|Q5T2B5|Q5T2B5_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 3 1054.6063 1.32 43198 20021 2 1054.607807 528.3104 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 8.75 3748.5 - 1.71E+06 - - - 1.4451 - 2.127 0.327 - 219.6 1 2 0 0.0015 9 0 0 0 5.76E+06 4.37E+06 - - - 3.6392 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.20022.20022.3 0.0122 16/40 R.AALLELWELR[166.11]R[166.11].Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1388.8043 0.63 43199 20022 3 1388.805821 463.942 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.19 3748.7 - 1.67E+06 - - - 1.088 - 2.59 0.323 - 562.6 1 2 0 0.0015 11 0 0 0 2.34E+06 3.72E+06 - - - 4.8442 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.20023.20023.2 0.0175 12-Jun K.LFFLQVK[136.11].E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 901.5517 0.82 43200 20023 2 901.552507 451.7831 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3748.8 - 1.47E+06 - - - 0.9229 - 1.389 0.286 - 106.5 1 2 0 0.0008 7 0 0 0 3.63E+06 4.42E+06 - - - 2.1943 0.9807 230117_WJC_METTL3_WT_vs_EV_F05.20024.20024.2 0.295 12-May K.LFFLQVK.E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 893.5375 0.82 43201 20024 2 893.537885 447.776 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3748.9 - 1.26E+06 - - - 0.4589 - 1.277 0.062 - 63.5 2 2 0 0.0004 7 0 0 0 3.63E+06 4.42E+06 - - - 0.1391 0.9953 230117_WJC_METTL3_WT_vs_EV_F05.20025.20025.2 1.88 14-Aug R.LLLEDLVK.K "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 941.5797 1.33 43202 20025 2 941.580552 471.7971 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 4.37 3749.1 - 1.09E+06 - - - 0.8688 - 1.35 0.151 - 123 1 2 0 0.0008 8 0 0 0 2.13E+06 1.60E+06 - - - 1.0611 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.20027.20027.2 0.00314 20-Sep R.YLLLLAAGDPR.E "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1200.6867 5.2 43204 20027 2 1200.684287 601.3506 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.84 3749.3 - 730044 - - - -1.9755 - 1.906 0.244 - 234.1 1 2 0 -0.0024 11 0 0 0 3.72E+06 7.16E+05 - - - 2.5873 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.20028.20028.2 0.176 12-Jul K.WLFTEIR.S "sp|P50851|LRBA_HUMAN,tr|E9PEM5|E9PEM5_HUMAN,tr|A0A494BZW2|A0A494BZW2_HUMAN,tr|A0A494C1L5|A0A494C1L5_HUMAN,tr|H0YAC6|H0YAC6_HUMAN" 5 963.5178 -1 43205 20028 2 963.518601 482.7662 Lipopolysaccharide-responsive and beige-like anchor protein OS=Homo sapiens OX=9606 GN=LRBA PE=1 SV=4 6 3749.4 - 592240 - - - 0.8293 - 1.281 0.205 - 170.1 1 2 0 0.0008 7 0 0 0 0.00E+00 0.00E+00 - - - 1.3395 1 230117_WJC_METTL3_WT_vs_EV_F05.20029.20029.2 2.29E-05 22-Sep K.C[160.03]PLDPYFIMPDK.C "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 3 1494.6887 -1 43206 20029 2 1494.687306 748.3516 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4.21 3749.6 - 578850 - - - -0.9387 - 1.978 0.583 - 162.6 1 2 0 -0.0014 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1413 1 230117_WJC_METTL3_WT_vs_EV_F05.20032.20032.2 9.50E-07 24-Nov R.FADALGLELAQVK.V sp|O95685|PPR3D_HUMAN 1 1373.7555 -1 43209 20032 2 1373.756739 687.885 Protein phosphatase 1 regulatory subunit 3D OS=Homo sapiens OX=9606 GN=PPP1R3D PE=1 SV=1 4.37 3750 - 542774 - - - 0.9259 - 2.325 0.508 - 287.5 1 2 0 0.0013 13 0 0 0 0.00E+00 0.00E+00 - - - 4.9581 0.9871 230117_WJC_METTL3_WT_vs_EV_F05.20040.20040.2 0.0108 13/22 K.LGAIFLEGVTVK.G sp|O60942|MCE1_HUMAN 1 1245.7333 13.29 43216 20040 2 1245.743902 623.8739 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 6 3751 - 1.83E+06 - - - 8.5307 - 2.406 0.428 - 536.7 1 2 0 0.0106 12 0 0 0 2.61E+06 1.96E+05 - - - 4.5089 0.9964 230117_WJC_METTL3_WT_vs_EV_F05.20042.20042.2 0.0116 16-Oct R.IQEFIELIR.Q "sp|Q7L5Y9|MAEA_HUMAN,tr|B4DVN3|B4DVN3_HUMAN,tr|B4DQT1|B4DQT1_HUMAN,tr|E7ESC7|E7ESC7_HUMAN,tr|D6RE80|D6RE80_HUMAN" 5 1159.6601 -1 43218 20042 2 1159.666563 580.8373 E3 ubiquitin-protein transferase MAEA OS=Homo sapiens OX=9606 GN=MAEA PE=1 SV=1 4.53 3751.2 - 745257 - - - 5.5646 - 2.233 0.328 - 313.4 1 2 0 0.0065 9 0 0 0 0.00E+00 0.00E+00 - - - 3.7857 0.995 230117_WJC_METTL3_WT_vs_EV_F05.20044.20044.2 0.27 12-Jul R.IIWQFIK.E "sp|P48735|IDHP_HUMAN,tr|H0YL11|H0YL11_HUMAN" 2 946.564 1.56 43220 20044 2 946.56779 474.2893 "Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2" 8.75 3751.5 - 570639 - - - 3.9786 - 1.268 0.301 - 132.3 1 2 0 0.0038 7 0 0 0 2.49E+06 1.60E+06 - - - 2.0153 0.9969 230117_WJC_METTL3_WT_vs_EV_F05.20045.20045.2 0.0766 14-Jul K.AIFLFVDK.T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 951.543 1.77 43221 20045 2 951.546076 476.7788 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3751.6 - 557448 - - - 3.281 - 1.251 0.313 - 154.5 1 2 0 0.0031 8 0 0 0 1.18E+07 6.62E+06 - - - 2.0272 0.9895 230117_WJC_METTL3_WT_vs_EV_F05.20046.20046.2 0.00294 16-Sep R.LTSFITVFK[136.11].Y "sp|Q13617|CUL2_HUMAN,tr|Q5T2B5|Q5T2B5_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 3 1062.6205 -1 43222 20046 2 1062.626699 532.3175 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 8.75 3751.7 - 556300 - - - 5.8497 - 2.015 0.203 - 191.2 1 2 0 0.0062 9 0 0 0 0.00E+00 0.00E+00 - - - 2.5653 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.20048.20048.2 0.00785 14-Jul K.AIFLFVDK[136.11].T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 959.5572 1.47 43224 20048 2 959.561327 480.7859 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3752 - 471180 - - - 4.3489 - 1.452 0.353 - 190.5 1 2 0 0.0042 8 0 0 0 5.35E+06 3.65E+06 - - - 2.7717 1 230117_WJC_METTL3_WT_vs_EV_F05.20050.20050.3 4.91E-09 16/72 K.LGGSLADSYLDEGFLLDKK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2040.0415 -1 43226 20050 3 2040.0483 681.0211 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.23 3752.3 - 398282 - - - 3.3146 - 2.883 0.592 - 265.9 1 2 0 0.0068 19 0 0 0 0.00E+00 0.00E+00 - - - 7.7397 0.999 230117_WJC_METTL3_WT_vs_EV_F05.20058.20058.2 0.00733 22-Nov K.ALFSLAPEVEVR.V "sp|Q8N3Z3|GTPB8_HUMAN,tr|C9J8V5|C9J8V5_HUMAN,tr|F8WBY6|F8WBY6_HUMAN" 3 1329.7293 -1 43233 20058 2 1329.734549 665.8719 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.53 3753.3 - 135628 - - - 3.9835 - 2.377 0.399 - 404 1 2 0 0.0053 12 0 0 0 0.00E+00 0.00E+00 - - - 4.2645 0.9301 230117_WJC_METTL3_WT_vs_EV_F05.20060.20060.2 0.068 24-Sep R.FNLTANQHLLAPG.F sp|Q9UKP4|ATS7_HUMAN 1 1394.7306 - 43235 20060 2 1394.732302 698.3726 A disintegrin and metalloproteinase with thrombospondin motifs 7 OS=Homo sapiens OX=9606 GN=ADAMTS7 PE=1 SV=2 6.74 3753.5 - 1.63E+06 - - - 1.1852 - 1.78 0.261 - 194.4 1 1 0 0.0017 13 0 0 0 - - - - - 2.4481 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.20062.20062.2 0.0242 18-Aug R.DIIALNPLYR.E "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN" 3 1186.671 -1 43237 20062 2 1186.669332 594.3428 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 5.84 3753.7 - 359024 - - - -1.4132 - 1.839 0.25 - 204.6 1 2 0 -0.0017 10 0 0 0 0.00E+00 0.00E+00 - - - 2.5875 1 230117_WJC_METTL3_WT_vs_EV_F05.20064.20064.2 0.173 18-Dec R.FC[160.03]IWTESAFR[166.11].K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1325.6102 -1 43239 20064 2 1325.613172 663.8124 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3754 - 353448 - - - 2.2322 - 2.422 0.523 - 647.9 1 2 0 0.003 10 0 0 0 0.00E+00 0.00E+00 - - - 5.3721 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.20069.20069.2 0.00354 18/22 R.ALLANALTSALR[166.11].L "sp|P57088|TMM33_HUMAN,tr|D6RAA6|D6RAA6_HUMAN" 2 1222.7273 1.21 43244 20069 2 1222.732201 612.3709 Transmembrane protein 33 OS=Homo sapiens OX=9606 GN=TMEM33 PE=1 SV=2 9.79 3754.6 - 229362 - - - 4.0156 - 2.61 0.251 - 1659.3 1 2 0 0.0049 12 0 0 0 8.52E+06 7.05E+06 - - - 3.4176 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20070.20070.2 0.00456 18-Nov R.FC[160.03]IWTESAFR.K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1315.6019 0.81 43245 20070 2 1315.604581 658.8082 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3754.8 - 221240 - - - 2.0052 - 2.095 0.45 - 568.9 1 2 0 0.0026 10 0 0 0 7.42E+06 9.18E+06 - - - 4.4282 1 230117_WJC_METTL3_WT_vs_EV_F05.20077.20077.2 5.83E-06 22-Dec K.FLQDTIEEMALK[136.11].N sp|O95202|LETM1_HUMAN 1 1444.7363 3.14 43252 20077 2 1444.739006 723.3754 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.14 3755.7 - 78591.5 - - - 1.8605 - 2.564 0.492 - 410 1 2 0 0.0027 12 0 0 0 8.21E+06 2.62E+06 - - - 5.1515 0.9938 230117_WJC_METTL3_WT_vs_EV_F05.20080.20080.2 0.000684 20-Aug K.LFPGFEIETVK.N "sp|P08243|ASNS_HUMAN,tr|F8WEJ5|F8WEJ5_HUMAN" 2 1278.686 -1 43254 20080 2 1278.693156 640.3503 Asparagine synthetase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=ASNS PE=1 SV=4 4.53 3756.1 - 599977 - - - 5.6042 - 1.638 0.355 - 180.7 1 2 0 0.0072 11 0 0 0 0.00E+00 0.00E+00 - - - 2.9957 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20081.20081.2 0.0238 18-Sep R.DLASVQALLR[166.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1094.6323 0.86 43255 20081 2 1094.634225 548.3234 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3756.1 - 4.03E+06 - - - 1.733 - 1.928 0.319 - 273.7 1 2 0 0.0019 10 0 0 0 1.15E+07 1.35E+07 - - - 3.229 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20082.20082.2 0.00942 18-Nov R.DLASVQALLR.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1084.6241 0.26 43256 20082 2 1084.626909 543.3193 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3756.2 - 3.52E+06 - - - 2.6286 - 2.538 0.368 - 430.4 1 2 0 0.0029 10 0 0 0 1.21E+07 4.61E+07 - - - 4.3579 0.999 230117_WJC_METTL3_WT_vs_EV_F05.20085.20085.2 0.102 14-Aug K.QDILTIFK[136.11].R "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV8|B0QYV8_HUMAN" 2 984.5735 -1 43259 20085 2 984.57562 493.294 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3756.4 - 1.29E+06 - - - 2.1197 - 1.63 0.274 - 219.3 1 2 0 0.0021 8 0 0 0 0.00E+00 0.00E+00 - - - 2.5376 1 230117_WJC_METTL3_WT_vs_EV_F05.20087.20087.2 4.24E-07 20-Dec R.FSYLAVIEGAK[136.11].F "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 1204.6583 -1 43261 20087 2 1204.660029 603.3364 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 6 3756.6 - 1.14E+06 - - - 1.4145 - 2.499 0.605 - 392.9 1 2 0 0.0017 11 0 0 0 0.00E+00 0.00E+00 - - - 5.9867 1 230117_WJC_METTL3_WT_vs_EV_F05.20091.20091.2 0.000293 14/24 R.ALDPAAAAYLFQR.Q "sp|O75376|NCOR1_HUMAN,tr|E7EVK1|E7EVK1_HUMAN" 2 1405.7354 -1 43265 20091 2 1405.741504 703.875 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 5.88 3757 - 598728 - - - 4.3422 - 2.949 0.442 - 909.2 1 2 0 0.0061 13 0 0 0 0.00E+00 0.00E+00 - - - 5.0793 0.9422 230117_WJC_METTL3_WT_vs_EV_F05.20095.20095.2 0.00201 22-Sep K.LLPELLQPYTER.V sp|Q13057|COASY_HUMAN 1 1470.8082 -1 43269 20095 2 1471.815097 736.4114 Bifunctional coenzyme A synthase OS=Homo sapiens OX=9606 GN=COASY PE=1 SV=4 4.53 3757.5 - 325089 - - - 684.5672 - 1.934 0.367 - 314.8 1 2 0 1.0069 12 0 0 0 0.00E+00 0.00E+00 - - - 3.171 1 230117_WJC_METTL3_WT_vs_EV_F05.20096.20096.2 0.00326 15/26 K.ALLAVIGADSVTLK.N sp|Q9NYH9|UTP6_HUMAN 1 1369.8181 -1 43270 20096 2 1369.818655 685.9163 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3757.6 - 278939 - - - 0.4293 - 3.003 0.404 - 874.3 1 2 0 0.0006 14 0 0 0 0.00E+00 0.00E+00 - - - 4.7842 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20097.20097.2 0.0272 26-Dec K.ALLAVIGADSVTLK[136.11].N sp|Q9NYH9|UTP6_HUMAN 1 1377.8323 -1 43271 20097 2 1377.833789 689.9234 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3757.8 - 255992 - - - 1.1046 - 2.434 0.339 - 551.8 1 2 0 0.0015 14 0 0 0 0.00E+00 0.00E+00 - - - 3.7766 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20100.20100.2 0.00657 12-Aug R.YGLVFFR.Q "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN,tr|F6WRY4|F6WRY4_HUMAN" 4 900.4858 1.01 43273 20100 2 900.487194 451.2502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.75 3758.1 - 935315 - - - 1.5769 - 1.844 0.244 - 276.8 1 2 0 0.0014 7 0 0 0 2.99E+06 2.96E+06 - - - 2.7817 1 230117_WJC_METTL3_WT_vs_EV_F05.20102.20102.2 0.000221 13/20 R.AFITNIPFDVK[136.11].W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1271.7005 2.56 43275 20102 2 1271.703203 636.8575 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3758.3 - 4.69E+06 - - - 2.1066 - 2.251 0.464 - 651.5 1 2 0 0.0027 11 0 0 0 5.19E+08 2.02E+08 - - - 4.6622 1 230117_WJC_METTL3_WT_vs_EV_F05.20104.20104.2 8.40E-10 15/28 L.LVSVSALTLATETVR.S sp|P50991|TCPD_HUMAN 1 1558.893 -1 43277 20104 2 1558.895632 780.4538 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6 3758.5 - 1.33E+06 - - - 1.6736 - 2.851 0.633 - 788.6 1 1 0 0.0026 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2913 1 230117_WJC_METTL3_WT_vs_EV_F05.20105.20105.2 1.61E-06 16/26 K.LLTGELLPTDGMIR.K sp|Q9UG63|ABCF2_HUMAN 1 1527.8331 -1 43278 20105 2 1527.836629 764.9238 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.37 3758.6 - 1.29E+06 - - - 2.3327 - 2.888 0.445 - 711.9 1 2 0 0.0036 14 0 0 0 0.00E+00 0.00E+00 - - - 4.9881 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20106.20106.2 0.0272 14-Aug K.EILIPVFK[136.11].N sp|P53396|ACLY_HUMAN 1 965.6041 1.35 43279 20106 2 965.606147 483.8093 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3758.7 - 1.26E+06 - - - 2.1147 - 1.545 0.407 - 214.5 1 2 0 0.002 8 0 0 0 3.52E+07 2.62E+07 - - - 3.3585 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20108.20108.2 0.000217 20-Nov R.ELGLGLGLGLK[136.11].E "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 1076.6685 0.97 43281 20108 2 1076.670341 539.3415 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 6.1 3759 - 805129 - - - 1.7136 - 2.064 0.41 - 284.4 1 2 0 0.0018 11 0 0 0 6.46E+06 6.64E+06 - - - 4.029 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.20109.20109.2 0.00276 12-Jul R.YGLVFFR[166.11].Q "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN,tr|F6WRY4|F6WRY4_HUMAN" 4 910.494 1.01 43282 20109 2 910.495185 456.2543 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.75 3759.1 - 778532 - - - 1.2532 - 1.664 0.244 - 204.8 1 2 0 0.0011 7 0 0 0 2.99E+06 2.96E+06 - - - 2.4563 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.20111.20111.2 0.0271 16-Sep R.ALQLLYDLR.Y "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1103.6339 1.11 43284 20111 2 1103.637009 552.8242 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.88 3759.4 - 610104 - - - 2.8216 - 2.091 0.232 - 361.9 1 2 0 0.0031 9 0 0 0 5.65E+06 5.10E+06 - - - 2.8876 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.20112.20112.3 9.00E-06 13/44 R.LLHLPLSLTALK.L sp|Q9BTT6|LRRC1_HUMAN 1 1317.8384 2.39 43285 20112 3 1317.841335 440.2867 Leucine-rich repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRRC1 PE=1 SV=1 8.76 3759.5 - 607463 - - - 2.2211 - 2.386 0.399 - 356.2 1 2 0 0.0029 12 0 0 0 2.17E+06 9.05E+05 - - - 5.3981 1 230117_WJC_METTL3_WT_vs_EV_F05.20113.20113.2 0.000441 15/26 K.LLTGELLPTDGMIR[166.11].K sp|Q9UG63|ABCF2_HUMAN 1 1537.8413 -1 43286 20113 2 1537.847022 769.9279 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.37 3759.6 - 590939 - - - 3.698 - 2.438 0.458 - 591.6 1 2 0 0.0057 14 0 0 0 0.00E+00 0.00E+00 - - - 4.6584 0.9681 230117_WJC_METTL3_WT_vs_EV_F05.20116.20116.2 0.00163 20-Dec R.ELGLGLGLGLK.E "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 1068.6543 0.97 43289 20116 2 1068.6641 535.3344 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 6.1 3760 - 518287 - - - 9.1742 - 2.108 0.266 - 364.3 1 2 0 0.0098 11 0 0 0 6.46E+06 6.64E+06 - - - 3.02 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20121.20121.2 0.000386 13/20 R.AFITNIPFDVK.W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1263.6863 2.56 43293 20121 2 1263.689293 632.8504 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3760.6 - 1.22E+08 - - - 2.3495 - 2.182 0.449 - 607.7 1 2 0 0.003 11 0 0 0 5.18E+08 2.02E+08 - - - 4.4671 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.20122.20122.2 0.0257 18-Nov R.LTTLELLEVR[166.11].R "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1195.7052 0.8 43294 20122 2 1195.707326 598.8599 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.53 3760.7 - 8.68E+06 - - - 1.8123 - 2.283 0.123 - 438.9 1 2 0 0.0022 10 0 0 0 2.11E+07 2.65E+07 - - - 2.253 0.9589 230117_WJC_METTL3_WT_vs_EV_F05.20123.20123.2 0.00114 16-Sep S.ALAFEQIIK[136.11].N "sp|Q8NCM8|DYHC2_HUMAN,sp|Q15643|TRIPB_HUMAN,tr|A0A3B3IT36|A0A3B3IT36_HUMAN,tr|A0A3B3ISP9|A0A3B3ISP9_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 5 1039.6157 1.21 43295 20123 2 1039.618251 520.8151 Cytoplasmic dynein 2 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC2H1 PE=1 SV=4 6.05 3760.7 - 2.12E+07 - - - 2.423 - 1.716 0.397 - 250.1 1 1 0 0.0025 9 0 0 0 7.80E+07 6.47E+07 - - - 3.5347 1 230117_WJC_METTL3_WT_vs_EV_F05.20127.20127.2 5.14E-08 14/24 K.ILTFDQLALDSPK[136.11].G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1467.8064 0.77 43299 20127 2 1467.80552 734.9105 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3761 - 3.64E+06 - - - -0.6309 - 2.77 0.521 - 529.2 1 2 0 -0.0009 13 0 0 0 7.28E+07 9.48E+07 - - - 5.5037 1 230117_WJC_METTL3_WT_vs_EV_F05.20129.20129.2 7.79E-05 15/24 K.ILTFDQLALDSPK.G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1459.7922 0.77 43301 20129 2 1459.793241 730.9034 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3761.3 - 2.47E+06 - - - 0.6816 - 2.829 0.559 - 751.4 1 2 0 0.001 13 0 0 0 7.28E+07 9.48E+07 - - - 5.8385 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.20130.20130.2 0.724 18-Oct K.LGLFPSNFVK.E sp|Q9Y5K6|CD2AP_HUMAN 1 1120.6281 1.37 43302 20130 2 1120.63072 561.3213 CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1 8.75 3761.4 - 2.21E+06 - - - 2.3549 - 1.977 0.308 - 222.9 1 2 0 0.0026 10 0 0 0 4.95E+06 3.62E+06 - - - 3.2176 1 230117_WJC_METTL3_WT_vs_EV_F05.20131.20131.2 5.05E-06 13/22 K.MFIGGLSWDTTK[136.11].K "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 1362.6733 1.07 43303 20131 2 1362.675256 682.3439 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 5.59 3761.5 - 2.02E+06 - - - 1.4185 - 2.229 0.548 - 437.9 1 2 0 0.0019 12 0 0 0 1.68E+07 1.57E+07 - - - 5.1969 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.20132.20132.2 1.64E-05 16-Oct R.DGFVC[160.03]ALLR.F "sp|Q8WUY1|THEM6_HUMAN,tr|H0YAR9|H0YAR9_HUMAN" 2 1049.5328 -1 43304 20132 2 1049.530844 525.7737 Protein THEM6 OS=Homo sapiens OX=9606 GN=THEM6 PE=1 SV=2 5.83 3761.7 - 1.80E+06 - - - -1.8646 - 1.656 0.537 - 287.7 1 2 0 -0.002 9 0 0 0 0.00E+00 0.00E+00 - - - 4.4659 0.9915 230117_WJC_METTL3_WT_vs_EV_F05.20134.20134.2 1.17 12-May R.DVFLMLK.K "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 864.4779 1.14 43306 20134 2 864.479243 433.2462 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 5.84 3761.9 - 1.32E+06 - - - 1.5408 - 1.06 0.185 - 91.4 1 2 0 0.0013 7 0 0 0 2.77E+06 2.42E+06 - - - 0.5916 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.20142.20142.2 0.00108 16-Aug K.MTILQTYFR.Q sp|O75348|VATG1_HUMAN 1 1171.606 1.31 43313 20142 2 1171.609258 586.8103 V-type proton ATPase subunit G 1 OS=Homo sapiens OX=9606 GN=ATP6V1G1 PE=1 SV=3 8.5 3762.9 - 1.48E+06 - - - 2.8107 - 1.82 0.336 - 200.4 1 2 0 0.0033 9 0 0 0 5.86E+06 4.48E+06 - - - 3.2541 0.9962 230117_WJC_METTL3_WT_vs_EV_F05.20144.20144.2 7.6 14-Jun R.LLLTPWVK[136.11].F sp|Q14152|EIF3A_HUMAN 1 976.6201 0.92 43315 20144 2 976.621609 489.3173 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.75 3763.1 - 6.12E+06 - - - 1.5564 - 1.42 0.147 - 87.3 1 2 0 0.0015 8 0 0 0 1.42E+07 1.54E+07 - - - 1.1838 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.20145.20145.2 0.0118 20-Nov R.VLPSIVNEVLK.S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1209.7333 1.26 43316 20145 2 1209.737482 605.8739 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3763.2 - 2.61E+06 - - - 3.4776 - 1.784 0.43 - 358.8 1 2 0 0.0042 11 0 0 0 9.67E+06 7.66E+06 - - - 3.7816 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20148.20148.2 0.00028 16-Sep K.LGFMSAFVK[136.11].A "sp|P36957|ODO2_HUMAN,tr|Q86SW4|Q86SW4_HUMAN" 2 1006.5401 0.88 43319 20148 2 1006.540811 504.2773 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 8.75 3763.5 - 1.70E+06 - - - 0.6825 - 1.944 0.36 - 202.2 1 2 0 0.0007 9 0 0 0 3.65E+06 4.13E+06 - - - 3.6229 0.9561 230117_WJC_METTL3_WT_vs_EV_F05.20151.20151.2 0.000392 16-Aug R.LFPLIQTMH.S "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 9 1098.5896 - 43322 20151 2 1098.592012 550.3021 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.74 3763.9 - 1.31E+06 - - - 2.2074 - 1.598 0.39 - 233.7 1 1 0 0.0024 9 0 0 0 - - - - - 3.2769 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20160.20160.3 0.00126 Sep-40 K.LLPQFLLHLDK[136.11].L "sp|Q8N4J0|CARME_HUMAN,tr|Q5T8V1|Q5T8V1_HUMAN,tr|Q5T8U9|Q5T8U9_HUMAN" 3 1343.8057 1.16 43331 20160 3 1343.807123 448.9425 Carnosine N-methyltransferase OS=Homo sapiens OX=9606 GN=CARNMT1 PE=1 SV=1 6.74 3765.1 - 404346 - - - 1.0902 - 1.747 0.367 - 102.7 1 2 0 0.0015 11 0 0 0 1.68E+06 1.44E+06 - - - 4.2162 0.9934 230117_WJC_METTL3_WT_vs_EV_F05.20163.20163.2 0.201 14-May K.EILIPVFK.N sp|P53396|ACLY_HUMAN 1 957.5899 1.35 43333 20163 2 957.591778 479.8022 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3765.4 - 1.70E+06 - - - 1.956 - 1.09 0.207 - 83 1 2 0 0.0019 8 0 0 0 3.52E+07 2.62E+07 - - - 0.8292 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.20164.20164.2 0.07 18-Jun R.EYLLDMIPPR.S "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 3 1245.6427 2.62 43334 20164 2 1245.645667 623.8286 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.37 3765.4 - 1.04E+06 - - - 2.3458 - 1.407 0.198 - 87.4 1 2 0 0.0029 10 0 0 0 3.73E+06 1.43E+06 - - - 1.4556 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20165.20165.2 3.48E-05 14-Aug R.DWVLNEFR[166.11].S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1087.5326 1.25 43335 20165 2 1087.533788 544.7736 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3765.5 - 3.13E+06 - - - 1.0795 - 1.811 0.325 - 368.9 1 2 0 0.0012 8 0 0 0 3.33E+07 2.66E+07 - - - 3.2322 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20167.20167.2 0.000207 14-Jul R.DWVLNEFR.S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1077.5243 1.25 43337 20167 2 1077.526009 539.7694 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3765.6 - 2.99E+06 - - - 1.5452 - 1.546 0.452 - 274.1 1 2 0 0.0017 8 0 0 0 3.33E+07 2.66E+07 - - - 3.6929 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20169.20169.2 0.00145 20-Sep R.VLPSIVNEVLK[136.11].S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1217.7475 1.26 43339 20169 2 1217.748598 609.881 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3765.7 - 1.35E+06 - - - 0.9222 - 1.904 0.447 - 273.2 1 2 0 0.0011 11 0 0 0 9.67E+06 7.66E+06 - - - 4.0842 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.20173.20173.2 0.0928 18-Aug R.LFALVLTPTR[166.11].E sp|Q9H0S4|DDX47_HUMAN 1 1139.6942 0.92 43343 20173 2 1139.695007 570.8544 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 9.75 3765.9 - 893309 - - - 0.7081 - 1.805 0.334 - 229.9 1 2 0 0.0008 10 0 0 0 5.50E+06 5.97E+06 - - - 3.1561 1 230117_WJC_METTL3_WT_vs_EV_F05.20174.20174.2 4.34E-05 20-Sep R.IPDQLVILDMK.H "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1283.7159 1.38 43344 20174 2 1283.718715 642.8652 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.21 3765.9 - 741950 - - - 2.1851 - 2.452 0.468 - 294.9 1 2 0 0.0028 11 0 0 0 4.25E+07 3.08E+07 - - - 4.9231 0.9906 230117_WJC_METTL3_WT_vs_EV_F05.20176.20176.2 0.0206 12-Jul R.FVFLLDR.G sp|Q13045|FLII_HUMAN 1 908.512 1.63 43346 20176 2 908.511762 455.2633 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3766.1 - 645953 - - - -0.2499 - 1.519 0.072 - 201.9 1 2 0 -0.0002 7 0 0 0 1.33E+07 8.13E+06 - - - 0.8973 0.991 230117_WJC_METTL3_WT_vs_EV_F05.20179.20179.2 0.182 14-May R.FSLDFNLR.T "sp|Q96MM3|ZFP42_HUMAN,sp|P25490|TYY1_HUMAN,sp|O15391|TYY2_HUMAN,tr|H0YJV7|H0YJV7_HUMAN" 4 1010.5185 -1 43349 20179 2 1010.521538 506.2665 Zinc finger protein 42 homolog OS=Homo sapiens OX=9606 GN=ZFP42 PE=1 SV=2 5.84 3766.2 - 376072 - - - 2.9757 - 1.11 0.219 - 60 1 2 0 0.003 8 0 0 0 0.00E+00 0.00E+00 - - - 0.9723 1 230117_WJC_METTL3_WT_vs_EV_F05.20189.20189.2 6.98E-07 28-Nov K.ELVGPPLAETVFTPK.T sp|P49792|RBP2_HUMAN 1 1596.8763 2.42 43357 20189 2 1596.881462 799.4454 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3767.2 - 49209.2 - - - 3.2263 - 2.215 0.55 - 308.4 1 2 0 0.0052 15 0 0 0 1.24E+07 5.11E+06 - - - 5.0568 0.8468 230117_WJC_METTL3_WT_vs_EV_F05.20192.20192.2 0.124 22-Jun R.NVYPEEMIVALR.E sp|Q5VT52|RPRD2_HUMAN 1 1432.7384 4.6 43360 20192 2 1432.73059 717.3765 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3767.6 - 0 - - - -5.4762 - 1.225 0.232 - 66.6 2 2 0 -0.0078 12 0 0 0 4.85E+06 1.05E+06 - - - 1.1516 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20195.20195.2 2.20E-05 28-Nov K.ELVGPPLAETVFTPK[136.11].T sp|P49792|RBP2_HUMAN 1 1604.8905 2.36 43363 20195 2 1604.89499 803.4525 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3768 - 0 - - - 2.7915 - 1.938 0.485 - 223.8 1 2 0 0.0045 15 0 0 0 1.21E+07 5.11E+06 - - - 4.2485 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.20196.20196.2 0.00245 22-Sep K.FTVLLMPNGPMR[166.11].L sp|Q9UQ80|PA2G4_HUMAN 1 1384.7235 -1 43364 20196 2 1384.729216 693.369 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 9.75 3768.1 - 0 - - - 4.151 - 2.018 0.341 - 239.6 1 2 0 0.0057 12 0 0 0 0.00E+00 0.00E+00 - - - 3.4052 0.9343 230117_WJC_METTL3_WT_vs_EV_F05.20198.20198.2 0.455 14-Aug R.LLNLELLR.Q sp|Q5JXC2|MIIP_HUMAN 1 982.6175 999 43366 20198 2 982.626259 492.316 Migration and invasion-inhibitory protein OS=Homo sapiens OX=9606 GN=MIIP PE=1 SV=3 6 3768.4 - 0 - - - 8.8977 - 1.875 0.162 - 144.1 1 2 0 0.0087 8 0 0 0 1.30E+06 0.00E+00 - - - 2.1306 1 230117_WJC_METTL3_WT_vs_EV_F05.20200.20200.2 0.000145 22-Nov R.DLAQDEAVWLER[166.11].G "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1453.7077 1.01 43368 20200 2 1453.714567 727.8611 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 3.92 3768.6 - 0 - - - 4.7389 - 2.434 0.492 - 405.1 1 2 0 0.0069 12 0 0 0 8.30E+05 8.22E+05 - - - 5.0133 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20205.20205.2 0.109 14-Aug K.VNLAELFK.G sp|P30044|PRDX5_HUMAN 1 932.5331 2.16 43371 20205 2 932.53395 467.2738 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.97 3769.3 - 915688 - - - 0.8922 - 1.955 0.359 - 223.3 1 2 0 0.0008 8 0 0 0 1.28E+08 5.94E+07 - - - 3.7142 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20210.20210.2 0.000344 20-Aug K.IVFAAGNFWGR.T sp|P04181|OAT_HUMAN 1 1236.6404 0.55 43376 20210 2 1236.641929 619.3275 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 9.75 3769.7 - 522936 - - - 1.255 - 1.72 0.455 - 217.2 1 2 0 0.0016 11 0 0 0 6.05E+06 1.11E+07 - - - 3.8683 0.9953 230117_WJC_METTL3_WT_vs_EV_F05.20219.20219.2 0.0165 12-Aug R.FVFLLDR[166.11].G sp|Q13045|FLII_HUMAN 1 918.5203 1.65 43383 20219 2 918.522027 460.2674 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3770.7 - 1.77E+06 - - - 1.9248 - 1.664 0.058 - 252.9 1 2 0 0.0018 7 0 0 0 1.31E+07 7.95E+06 - - - 1.0823 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20221.20221.2 0.00495 18-Nov K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.73 43385 20221 2 1168.708302 585.3606 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3770.8 - 2.54E+06 - - - 1.3494 - 2.224 0.399 - 343.9 1 2 0 0.0016 10 0 0 0 3.24E+09 1.87E+09 - - - 4.2186 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.20222.20222.2 0.0274 18-Oct K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.73 43386 20222 2 1176.721359 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3770.9 - 2.13E+06 - - - 0.3688 - 2.137 0.284 - 250.9 1 2 0 0.0004 10 0 0 0 3.24E+09 1.87E+09 - - - 3.2582 1 230117_WJC_METTL3_WT_vs_EV_F05.20223.20223.2 2.40E-05 15/26 K.LLAESVTEVEIFGK.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1533.829 1.29 43387 20223 2 1533.831023 767.9218 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 3771 - 1.54E+06 - - - 1.302 - 2.937 0.529 - 736.1 1 2 0 0.002 14 0 0 0 1.06E+07 8.23E+06 - - - 5.6512 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.20224.20224.2 0.0218 24-Dec R.LAALPNVYEVISK.S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1415.8024 2.85 43388 20224 2 1415.805335 708.9085 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3771.1 - 1.24E+06 - - - 2.061 - 2.339 0.255 - 334 1 2 0 0.0029 13 0 0 0 1.18E+07 4.14E+06 - - - 3.1044 1 230117_WJC_METTL3_WT_vs_EV_F05.20225.20225.2 1.23E-06 15/26 K.LLAESVTEVEIFGK[136.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1541.8432 1.27 43389 20225 2 1541.844413 771.9289 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 3771.2 - 1.14E+06 - - - 0.7699 - 2.717 0.522 - 683 1 2 0 0.0012 14 0 0 0 1.05E+07 8.23E+06 - - - 5.4044 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.20226.20226.2 0.0184 14-Aug R.LFSWLVNR.L "sp|O43795|MYO1B_HUMAN,sp|Q8WXR4|MYO3B_HUMAN,tr|F5H2J1|F5H2J1_HUMAN,tr|A0A0U1RRI3|A0A0U1RRI3_HUMAN,tr|E9PDF6|E9PDF6_HUMAN" 5 1033.5709 0.96 43390 20226 2 1033.571197 517.7927 Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3 9.75 3771.3 - 902777 - - - 0.2864 - 1.682 0.311 - 174.7 1 2 0 0.0003 8 0 0 0 2.66E+06 2.78E+06 - - - 2.9062 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.20228.20228.2 0.000401 16-Sep R.DSVVLSLLK.Q sp|O43264|ZW10_HUMAN 1 972.5855 1.36 43392 20228 2 972.585062 487.3001 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 5.84 3771.5 - 778002 - - - -0.4997 - 1.573 0.446 - 262.3 1 2 0 -0.0005 9 0 0 0 3.70E+06 2.72E+06 - - - 3.6455 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.20229.20229.2 0.00263 24-Nov R.LAALPNVYEVISK[136.11].S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1423.8166 2.85 43393 20229 2 1423.820856 712.9156 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3771.6 - 761265 - - - 2.9772 - 2.116 0.336 - 318.9 1 2 0 0.0042 13 0 0 0 1.18E+07 4.14E+06 - - - 3.445 1 230117_WJC_METTL3_WT_vs_EV_F05.20230.20230.2 1.56E-10 19/36 R.YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2108.0769 1.61 43394 20230 2 2108.077266 1055.0457 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3771.7 - 722786 - - - 0.1893 - 3.922 0.689 - 981.5 1 2 0 0.0004 19 0 0 0 2.42E+06 1.51E+06 - - - 7.4897 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20231.20231.2 0.000577 18-Jul K.NGFLLDGFPR.T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1134.5822 1.6 43395 20231 2 1134.584029 568.2984 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3771.8 - 721120 - - - 1.6173 - 1.576 0.339 - 179 1 2 0 0.0018 10 0 0 0 1.07E+07 6.70E+06 - - - 2.814 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20232.20232.2 0.0116 16-Nov K.QVDLIDLVR.W sp|Q9UKN8|TF3C4_HUMAN 1 1069.6132 1.74 43396 20232 2 1069.614271 535.8139 General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2 4.21 3771.9 - 706666 - - - 1.0396 - 2.04 0.356 - 422.5 1 2 0 0.0011 9 0 0 0 7.73E+06 4.45E+06 - - - 3.7327 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.20233.20233.2 0.00113 16-Aug R.DSVVLSLLK[136.11].Q sp|O43264|ZW10_HUMAN 1 980.5997 1.36 43397 20233 2 980.599647 491.3072 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 5.84 3772 - 514303 - - - -0.103 - 1.761 0.402 - 191.5 1 2 0 -0.0001 9 0 0 0 3.70E+06 2.72E+06 - - - 3.6473 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.20237.20237.2 0.00017 22-Oct R.DLAQDEAVWLER.G "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1443.6994 1.01 43401 20237 2 1443.697884 722.857 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 3.92 3772.6 - 320120 - - - -1.0556 - 1.689 0.398 - 232.7 1 2 0 -0.0015 12 0 0 0 8.30E+05 8.22E+05 - - - 3.3592 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20240.20240.2 3.15E-06 18-Nov R.TLVEDLFADK.H "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1149.5918 1.11 43403 20240 2 1149.594209 575.8032 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.03 3772.9 - 320332 - - - 2.1347 - 1.999 0.366 - 280.9 1 2 0 0.0025 10 0 0 0 1.66E+07 1.50E+07 - - - 3.6769 0.9899 230117_WJC_METTL3_WT_vs_EV_F05.20248.20248.2 0.293 14-Aug R.YLIYDIIK.F sp|O60942|MCE1_HUMAN 1 1039.5954 999 43409 20248 2 1039.593917 520.805 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 5.83 3773.9 - 774463 - - - -1.4111 - 1.338 0.201 - 174.3 1 2 0 -0.0015 8 0 0 0 8.18E+06 0.00E+00 - - - 1.4033 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20250.20250.2 0.335 20-Oct R.LEYC[160.03]EALAMLR.E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1367.6577 1.58 43411 20250 2 1367.659361 684.8361 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3774.2 - 636700 - - - 1.183 - 2.107 0.299 - 344.4 1 2 0 0.0016 11 0 0 0 8.84E+06 5.58E+06 - - - 3.265 1 230117_WJC_METTL3_WT_vs_EV_F05.20251.20251.2 0.00054 20-Dec R.LEYC[160.03]EALAMLR[166.11].E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1377.666 1.58 43412 20251 2 1377.666971 689.8403 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3774.3 - 507508 - - - 0.6954 - 2.512 0.491 - 771.6 1 2 0 0.001 11 0 0 0 8.84E+06 5.58E+06 - - - 5.159 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.20252.20252.2 0.0019 18-Dec R.VDILDPALLR.S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1123.6601 2 43413 20252 2 1123.664971 562.8373 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3774.4 - 498313 - - - 4.326 - 2.599 0.375 - 463.1 1 2 0 0.0049 10 0 0 0 8.68E+07 4.34E+07 - - - 4.4753 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20253.20253.2 0.0502 18-Oct R.GLAVFISDIR.N "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|M0R2D9|M0R2D9_HUMAN,tr|E9PR62|E9PR62_HUMAN" 4 1089.6182 1.51 43414 20253 2 1089.621916 545.8164 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 5.84 3774.6 - 494671 - - - 3.3691 - 2.397 0.35 - 441.7 1 2 0 0.0037 10 0 0 0 9.21E+06 6.11E+06 - - - 4.0652 1 230117_WJC_METTL3_WT_vs_EV_F05.20254.20254.2 4.07E-07 14/24 R.LPSDVVTGYLALR.K "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1402.782 1.52 43415 20254 2 1402.783445 702.3983 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 5.84 3774.7 - 494575 - - - 1.0187 - 2.794 0.536 - 855.1 1 2 0 0.0014 13 0 0 0 6.34E+06 4.17E+06 - - - 5.6365 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.20256.20256.3 0.0326 Sep-36 K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.28 43417 20256 3 1168.708195 390.5762 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3774.9 - 370817 - - - 1.2578 - 1.895 0.265 - 82.7 1 2 0 0.0015 10 0 0 0 1.22E+07 9.54E+06 - - - 3.3609 1 230117_WJC_METTL3_WT_vs_EV_F05.20259.20259.2 0.000111 13/26 K.GLIGNLYLNDSPLK[136.11].N sp|Q8IW92|GLBL2_HUMAN 1 1523.8439 1 43420 20259 2 1523.847688 762.9292 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 5.83 3775.3 - 267840 - - - 2.4898 - 2.76 0.476 - 720.5 1 2 0 0.0038 14 0 0 0 1.67E+06 1.66E+06 - - - 5.1032 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.20260.20260.3 0.0014 Nov-36 K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.28 43421 20260 3 1176.722137 393.2476 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3775.5 - 220154 - - - 1.03 - 2.14 0.366 - 129.4 1 2 0 0.0012 10 0 0 0 1.22E+07 9.54E+06 - - - 4.8421 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.20264.20264.2 4.92E-06 24-Nov K.VLNSQAYLLFYER[166.11].L sp|Q9Y5T5|UBP16_HUMAN 1 1624.8489 -1 43425 20264 2 1624.850259 813.4317 Ubiquitin carboxyl-terminal hydrolase 16 OS=Homo sapiens OX=9606 GN=USP16 PE=1 SV=1 5.97 3776 - 198582 - - - 0.8592 - 2.112 0.241 - 274.9 1 2 0 0.0014 13 0 0 0 0.00E+00 0.00E+00 - - - 2.7394 0.9134 230117_WJC_METTL3_WT_vs_EV_F05.20265.20265.2 0.015 12-Jun R.TFHIFYY.M "sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 3 989.4647 - 43426 20265 2 989.466757 495.7396 Myosin-11 OS=Homo sapiens OX=9606 GN=MYH11 PE=1 SV=3 6.4 3776.1 - 91532.5 - - - 2.0749 - 1.246 0.352 - 124.3 1 1 0 0.0021 7 0 0 0 - - - - - 2.3371 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.20270.20270.2 0.12 18-Nov R.VDILDPALLR[166.11].S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1133.6684 2 43430 20270 2 1133.667432 567.8415 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3776.6 - 7.82E+06 - - - -0.8362 - 2.271 0.338 - 386.2 1 2 0 -0.0009 10 0 0 0 8.68E+07 4.34E+07 - - - 3.8267 1 230117_WJC_METTL3_WT_vs_EV_F05.20271.20271.2 1.08E-05 13/22 R.GNSIIMLEALER.V "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1344.7071 1.15 43431 20271 2 1344.704822 673.3608 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3776.7 - 5.12E+06 - - - -1.7208 - 2.712 0.557 - 742.5 1 2 0 -0.0023 12 0 0 0 2.09E+07 1.81E+07 - - - 5.7794 1 230117_WJC_METTL3_WT_vs_EV_F05.20272.20272.2 2.17E-06 13/22 R.GNSIIMLEALER[166.11].V "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1354.7154 1.15 43432 20272 2 1354.713424 678.365 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3776.7 - 4.27E+06 - - - -1.463 - 2.84 0.552 - 794.8 1 2 0 -0.002 12 0 0 0 2.09E+07 1.81E+07 - - - 5.8639 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.20274.20274.2 0.00469 18-Aug K.DFLLQQTMLR[166.11].V sp|Q04760|LGUL_HUMAN 1 1273.6728 1.2 43434 20274 2 1273.671423 637.8437 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 5.84 3776.9 - 2.89E+06 - - - -1.0913 - 1.833 0.265 - 231.7 1 2 0 -0.0014 10 0 0 0 1.02E+07 8.43E+06 - - - 2.6893 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.20278.20278.2 0.00202 14-Aug R.GFC[160.03]FITFK[136.11].E "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1026.5088 0.99 43437 20278 2 1026.508843 514.2617 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.22 3777.3 - 1.43E+06 - - - 0.0185 - 1.54 0.447 - 250.2 1 2 0 0 8 0 0 0 1.81E+08 1.82E+08 - - - 3.6448 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20281.20281.2 0.00134 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 2376.96 43439 20281 2 1603.763378 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3777.6 - 1.09E+06 - - - -0.3504 - 1.869 0.463 - 240.4 1 2 0 -0.0006 12 0 0 0 4.06E+09 1.71E+06 - - - 4.1061 0.9821 230117_WJC_METTL3_WT_vs_EV_F05.20282.20282.2 2.25 14-Aug K.NFLSTLIK[136.11].L sp|O00268|TAF4_HUMAN 1 942.563 1.38 43440 20282 2 942.563216 472.2888 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 8.75 3777.8 - 2.47E+06 - - - 0.2631 - 1.373 0.052 - 144.4 2 2 0 0.0002 8 0 0 0 3.10E+07 2.25E+07 - - - 0.2466 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20283.20283.2 0.158 16-Aug R.SIQMLTLLR.A "sp|Q13445|TMED1_HUMAN,tr|K7EIN4|K7EIN4_HUMAN,tr|K7EQ63|K7EQ63_HUMAN" 3 1073.6267 1.03 43441 20283 2 1073.627042 537.8206 Transmembrane emp24 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TMED1 PE=1 SV=1 9.47 3777.9 - 897144 - - - 0.3176 - 1.855 0.379 - 228.7 1 2 0 0.0003 9 0 0 0 5.20E+06 5.04E+06 - - - 3.6278 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20284.20284.2 1.41E-06 22-Oct R.LLVFGGMVEYGK.Y "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 1311.6897 4.58 43442 20284 2 1311.690903 656.8521 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 6 3778 - 703861 - - - 0.9209 - 1.826 0.522 - 286.8 1 2 0 0.0012 12 0 0 0 4.05E+06 8.83E+05 - - - 4.4804 1 230117_WJC_METTL3_WT_vs_EV_F05.20291.20291.2 2.57E-05 22-Oct R.LLVFGGMVEYGK[136.11].Y "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 1319.7039 -1 43449 20291 2 1319.700876 660.8592 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 6 3778.9 - 340154 - - - -2.2876 - 1.906 0.538 - 290.4 1 2 0 -0.003 12 0 0 0 0.00E+00 0.00E+00 - - - 4.7108 1 230117_WJC_METTL3_WT_vs_EV_F05.20293.20293.2 6.37E-07 22-Oct R.GYELLFQPEVVR.L "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A804HJM1|A0A804HJM1_HUMAN,tr|A0A804HK15|A0A804HK15_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN,tr|A0A804HIL4|A0A804HIL4_HUMAN" 8 1448.7664 0.74 43451 20293 2 1448.768042 725.3905 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 4.53 3779.2 - 286908 - - - 1.1568 - 2.266 0.508 - 369.1 1 2 0 0.0017 12 0 0 0 1.80E+06 2.44E+06 - - - 4.9449 0.9457 230117_WJC_METTL3_WT_vs_EV_F05.20298.20298.2 3.31 14-Jul K.QFLPFLQR[166.11].A "sp|Q7KZF4|SND1_HUMAN,tr|H7C597|H7C597_HUMAN" 2 1057.5948 1.29 43455 20298 2 1057.598144 529.8047 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 9.75 3779.8 - 168609 - - - 3.142 - 1.081 0.069 - 115.2 1 2 0 0.0033 8 0 0 0 2.02E+07 1.57E+07 - - - -0.2155 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.20303.20303.3 2.18E-07 16/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 5000.37 43458 20303 3 1603.7637 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3780.4 - 806838 - - - -0.1496 - 2.626 0.527 - 365.6 1 2 0 -0.0002 12 0 0 0 4.41E+08 8.81E+04 - - - 7.0916 1 230117_WJC_METTL3_WT_vs_EV_F05.20306.20306.2 3.45E-11 14/24 R.WSTLVEDYGMELR.K sp|O00232|PSD12_HUMAN 1 1597.7446 1.75 43461 20306 2 1597.742051 799.8796 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.14 3780.8 - 253222 - - - -1.6229 - 2.776 0.685 - 771 1 2 0 -0.0026 13 0 0 0 5.13E+06 2.93E+06 - - - 6.7201 1 230117_WJC_METTL3_WT_vs_EV_F05.20308.20308.2 1.32E-08 16/34 K.IAIIGAGIGGTSAAYYLR.Q "sp|Q9UHG3|PCYOX_HUMAN,tr|F8W8W4|F8W8W4_HUMAN" 2 1765.9727 3.03 43463 20308 2 1765.97525 883.9936 Prenylcysteine oxidase 1 OS=Homo sapiens OX=9606 GN=PCYOX1 PE=1 SV=3 8.59 3781.1 - 249240 - - - 1.461 - 3.206 0.585 - 708.6 1 2 0 0.0026 18 0 0 0 2.48E+06 8.17E+05 - - - 6.2253 1 230117_WJC_METTL3_WT_vs_EV_F05.20311.20311.2 0.000529 14/24 R.LAAVALINAAIQK[136.11].G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1302.8115 1.12 43466 20311 2 1302.812438 652.413 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3781.4 - 194376 - - - 0.7415 - 2.643 0.433 - 716.8 1 2 0 0.001 13 0 0 0 5.30E+06 4.73E+06 - - - 4.7333 0.9945 230117_WJC_METTL3_WT_vs_EV_F05.20313.20313.2 3.16 22-Nov R.FGPLTPELMVPR[166.11].L "sp|P40937|RFC5_HUMAN,tr|F5H5S0|F5H5S0_HUMAN" 2 1365.7354 5.18 43468 20313 2 1365.737438 683.875 Replication factor C subunit 5 OS=Homo sapiens OX=9606 GN=RFC5 PE=1 SV=1 6 3781.7 - 181024 - - - 1.4827 - 1.523 0.103 - 287.4 1 2 0 0.002 12 0 0 0 1.09E+07 2.11E+06 - - - 0.908 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20314.20314.2 8.50E-07 13/20 R.VYGALMWSLGK.V "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|C9JDQ8|C9JDQ8_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 7 1223.6373 3.27 43469 20314 2 1223.637528 612.8259 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 8.56 3781.8 - 165880 - - - 0.2141 - 2.15 0.412 - 479 1 2 0 0.0003 11 0 0 0 3.38E+06 1.04E+06 - - - 4.1547 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20317.20317.2 0.0259 14-Jul R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 8.45 43471 20317 2 1000.561238 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3782.3 - 97539 - - - 1.9039 - 1.773 0.293 - 158.6 1 2 0 0.0019 8 0 0 0 1.42E+06 1.68E+05 - - - 2.9317 1 230117_WJC_METTL3_WT_vs_EV_F05.20322.20322.2 0.00438 14/24 R.LAAVALINAAIQK.G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1294.7973 1.12 43474 20322 2 1294.795281 648.4059 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3782.8 - 2.30E+06 - - - -1.5377 - 3.134 0.403 - 673.1 1 2 0 -0.002 13 0 0 0 5.30E+06 4.73E+06 - - - 4.9487 1 230117_WJC_METTL3_WT_vs_EV_F05.20326.20326.2 4.70E-05 14/22 K.TVLLLADQMISR.L "sp|P48730|KC1D_HUMAN,sp|P49674|KC1E_HUMAN,tr|B0QY36|B0QY36_HUMAN,tr|B0QY34|B0QY34_HUMAN,tr|H7BYT1|H7BYT1_HUMAN,tr|J3QQI9|J3QQI9_HUMAN,tr|A0A669KBC0|A0A669KBC0_HUMAN,tr|H0Y645|H0Y645_HUMAN,tr|B0QY35|B0QY35_HUMAN,tr|H0Y2N6|H0Y2N6_HUMAN" 10 1358.7592 2 43478 20326 2 1358.761153 680.3869 Casein kinase I isoform delta OS=Homo sapiens OX=9606 GN=CSNK1D PE=1 SV=2 5.5 3783.3 - 1.35E+06 - - - 1.4579 - 2.98 0.513 - 864.9 1 2 0 0.002 12 0 0 0 3.41E+06 1.70E+06 - - - 5.7024 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20329.20329.3 0.0088 Dec-48 R.LAAVALINAAIQK.G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1294.7973 -1 43481 20329 3 1294.797383 432.6064 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3783.7 - 1.06E+06 - - - 0.0857 - 2.05 0.319 - 211 1 2 0 0.0001 13 0 0 0 0.00E+00 0.00E+00 - - - 4.0428 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.20331.20331.3 0.1 Dec-48 R.LAAVALINAAIQK[136.11].G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1302.8115 -1 43483 20331 3 1302.811084 435.2778 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3784 - 842064 - - - -0.2978 - 2.376 0.199 - 294.6 1 2 0 -0.0004 13 0 0 0 0.00E+00 0.00E+00 - - - 3.1049 0.9936 230117_WJC_METTL3_WT_vs_EV_F05.20333.20333.2 0.478 12-Aug K.LWDLYLR[166.11].T "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 987.5417 1.71 43485 20333 2 987.540271 494.7781 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.84 3784.3 - 823435 - - - -1.4693 - 1.677 0.156 - 270.6 1 2 0 -0.0015 7 0 0 0 3.23E+06 1.88E+06 - - - 1.8309 1 230117_WJC_METTL3_WT_vs_EV_F05.20334.20334.2 2.44E-05 14/24 R.TLVSGLLLEDSVR.V sp|A0A2Z4LIS9|FXO3B_HUMAN 1 1400.7875 2.53 43486 20334 2 1400.785947 701.401 Forkhead box protein O3B OS=Homo sapiens OX=9606 GN=FOXO3B PE=1 SV=1 4.37 3784.4 - 645246 - - - -1.1051 - 2.8 0.475 - 571.1 1 2 0 -0.0015 13 0 0 0 2.56E+06 1.01E+06 - - - 5.1914 0.9525 230117_WJC_METTL3_WT_vs_EV_F05.20336.20336.2 1.38 16-Apr K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 5.49 43488 20336 2 1014.536835 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3784.6 - 584723 - - - 2.2276 - 0.975 0.122 - 50.5 5 2 0 0.0023 9 0 0 0 4.86E+06 8.84E+05 - - - -0.4441 1 230117_WJC_METTL3_WT_vs_EV_F05.20338.20338.2 1.15E-05 24-Oct R.VDLNEEETILIIR.R "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A0U1RQE1|A0A0U1RQE1_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A0U1RQZ9|A0A0U1RQZ9_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8YCY3|A0A2R8YCY3_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YDA1|A0A2R8YDA1_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8YFV8|A0A2R8YFV8_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A2R8Y4R6|A0A2R8Y4R6_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 25 1555.8457 -1 43490 20338 2 1555.848388 778.9301 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4 3784.9 - 484605 - - - 1.7033 - 2.31 0.505 - 400.1 1 2 0 0.0027 13 0 0 0 0.00E+00 0.00E+00 - - - 4.9189 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.20345.20345.2 0.161 18-Jun K.INEWLTLVEK[136.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1251.6954 1.22 43496 20345 2 1251.696363 626.855 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.53 3785.6 - 1.14E+06 - - - 0.7382 - 1.2 0.219 - 150.9 1 2 0 0.0009 10 0 0 0 4.51E+06 3.71E+06 - - - 1.1672 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.20346.20346.2 0.0478 12-Jun R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 1.6 43497 20346 2 808.432179 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 3785.7 - 937978 - - - -1.1021 - 1.331 0.271 - 80.4 1 2 0 -0.0009 7 0 0 0 1.10E+07 6.87E+06 - - - 1.9483 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.20347.20347.2 0.0103 12-Aug K.LWDLYLR.T "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 977.5335 1.41 43498 20347 2 977.535052 489.774 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.84 3785.7 - 825416 - - - 1.6368 - 1.712 0.165 - 311.3 1 2 0 0.0016 7 0 0 0 3.91E+06 2.77E+06 - - - 1.9628 1 230117_WJC_METTL3_WT_vs_EV_F05.20348.20348.2 3.01E-08 17/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 43499 20348 2 1343.615342 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3785.8 - 737103 - - - 2.8877 - 2.983 0.535 - 1174.5 1 1 0 0.0039 10 0 0 0 1.82E+07 0.00E+00 - - - 6.042 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20349.20349.2 0.000333 20-Oct K.SIDPALSMLIK.S sp|Q9H501|ESF1_HUMAN 1 1186.6631 1.43 43500 20349 2 1186.663516 594.3388 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 5.55 3785.9 - 590596 - - - 0.3118 - 2.155 0.45 - 202.2 1 2 0 0.0004 11 0 0 0 3.20E+06 2.23E+06 - - - 4.4416 0.9318 230117_WJC_METTL3_WT_vs_EV_F05.20350.20350.2 1.43 28-Jun R.AGILTFC[160.03]VGASQANK.A sp|P12111|CO6A3_HUMAN 1 1535.7766 24.38 43501 20350 2 1535.778354 768.8956 Collagen alpha-3(VI) chain OS=Homo sapiens OX=9606 GN=COL6A3 PE=1 SV=5 8.27 3786 - 365670 - - - 1.1336 - 1.116 0.082 - 35 39 2 0 0.0017 15 0 0 0 1.86E+06 7.63E+04 - - - -0.7948 1 230117_WJC_METTL3_WT_vs_EV_F05.20362.20362.2 0.00827 14/22 K.VESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1404.75 1.48 43512 20362 2 1404.747324 703.3823 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3787.5 - 425941 - - - -1.9384 - 2.806 0.472 - 751.5 1 2 0 -0.0027 12 0 0 0 1.05E+07 7.13E+06 - - - 5.2411 0.9955 230117_WJC_METTL3_WT_vs_EV_F05.20369.20369.2 0.00324 16-Sep K.ELALSALLK[136.11].F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 964.6048 1.02 43519 20369 2 964.60199 483.3097 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3788.4 - 135372 - - - -2.9473 - 1.821 0.338 - 291.8 1 2 0 -0.0028 9 0 0 0 2.66E+07 2.61E+07 - - - 3.2706 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20370.20370.2 0.0448 20-Sep R.YLLLGQGDFIR.H "sp|Q96CW5|GCP3_HUMAN,tr|A0A3B3ITE3|A0A3B3ITE3_HUMAN" 2 1293.7081 -1 43520 20370 2 1293.708531 647.8613 Gamma-tubulin complex component 3 OS=Homo sapiens OX=9606 GN=TUBGCP3 PE=1 SV=2 5.84 3788.5 - 126315 - - - 0.3161 - 2.114 0.437 - 294.1 1 2 0 0.0004 11 0 0 0 0.00E+00 0.00E+00 - - - 4.2936 0.999 230117_WJC_METTL3_WT_vs_EV_F05.20374.20374.2 0.000493 16-Oct K.ELALSALLK.F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 956.5906 1.02 43524 20374 2 956.589489 479.3026 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3789 - 92857 - - - -1.1959 - 1.981 0.394 - 346.9 1 2 0 -0.0011 9 0 0 0 2.66E+07 2.61E+07 - - - 3.9284 0.999 230117_WJC_METTL3_WT_vs_EV_F05.20378.20378.2 0.000219 18-Aug K.GPDWILGEIK[136.11].T "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 6 1134.6165 -1 43527 20378 2 1134.620332 568.3155 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 4.37 3789.5 - 0 - - - 3.4126 - 1.798 0.371 - 153.3 1 2 0 0.0039 10 0 0 0 0.00E+00 0.00E+00 - - - 3.4176 0.986 230117_WJC_METTL3_WT_vs_EV_F05.20384.20384.2 0.809 14-Jul R.KIPVPANR[166.11].Y "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 903.553 - 43533 20384 2 903.554129 452.7838 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 11 3789.9 - 738825 - - - 1.2982 - 1.534 0.006 - 156.5 2 2 0 0.0012 8 0 0 0 - - - - - 0.2409 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.20389.20389.2 0.0741 16-Jul K.EIIDLVLDR.L "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 9 1084.6128 3.07 43536 20389 2 1084.612095 543.3137 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.03 3790.5 - 7.56E+07 - - - -0.6731 - 1.596 0.234 - 223.4 1 2 0 -0.0007 9 0 0 0 3.20E+08 1.04E+08 - - - 2.1216 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20390.20390.2 0.00911 16-Aug K.EIIDLVLDR[166.11].L "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 9 1094.6211 3.07 43537 20390 2 1094.622031 548.3178 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.03 3790.5 - 2.68E+07 - - - 0.8551 - 1.736 0.349 - 240.2 1 2 0 0.0009 9 0 0 0 3.20E+08 1.04E+08 - - - 3.2142 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.20391.20391.2 0.00568 20-Dec K.IGPITPLEFYR.E "sp|Q13867|BLMH_HUMAN,tr|K7ESE8|K7ESE8_HUMAN,tr|J3KSD8|J3KSD8_HUMAN,tr|K7ES02|K7ES02_HUMAN" 4 1304.7129 9.47 43538 20391 2 1304.709905 653.3637 Bleomycin hydrolase OS=Homo sapiens OX=9606 GN=BLMH PE=1 SV=1 6 3790.6 - 4.42E+06 - - - -2.2748 - 2.14 0.348 - 357 1 2 0 -0.003 11 0 0 0 2.26E+07 2.39E+06 - - - 3.6686 1 230117_WJC_METTL3_WT_vs_EV_F05.20395.20395.2 8.97E-06 22-Dec R.LLTFMGMAVENK[136.11].E "sp|Q7L2H7|EIF3M_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 2 1360.6974 0.8 43542 20395 2 1360.692945 681.356 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6 3791.1 - 2.75E+06 - - - -3.2961 - 2.433 0.581 - 473.2 1 2 0 -0.0045 12 0 0 0 6.87E+06 8.64E+06 - - - 5.6703 1 230117_WJC_METTL3_WT_vs_EV_F05.20396.20396.2 2.43E-05 18-Oct -.MFLYNLTLQR.A "sp|Q15393|SF3B3_HUMAN,tr|H3BMB0|H3BMB0_HUMAN,tr|I3L4G7|I3L4G7_HUMAN" 3 1297.6853 0.15 43543 20396 2 1297.681673 649.8499 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.5 3791.3 - 2.53E+06 - - - -2.778 - 2.252 0.525 - 378.3 1 2 0 -0.0036 10 0 0 0 1.22E+07 8.02E+07 - - - 5.1836 0.9944 230117_WJC_METTL3_WT_vs_EV_F05.20397.20397.2 0.0158 18-Sep K.AEVLWLMGAK.S sp|O94906|PRP6_HUMAN 1 1116.6002 1.05 43544 20397 2 1116.595967 559.3074 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.05 3791.4 - 2.44E+06 - - - -3.748 - 1.91 0.391 - 326.2 1 2 0 -0.0042 10 0 0 0 9.51E+06 9.07E+06 - - - 3.7339 0.985 230117_WJC_METTL3_WT_vs_EV_F05.20400.20400.2 0.00195 18-Oct K.AEVLWLMGAK[136.11].S sp|O94906|PRP6_HUMAN 1 1124.6144 1.09 43547 20400 2 1124.613925 563.3145 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.05 3791.8 - 2.17E+06 - - - -0.3797 - 1.699 0.012 - 324.9 1 2 0 -0.0004 10 0 0 0 1.01E+07 9.21E+06 - - - 0.609 1 230117_WJC_METTL3_WT_vs_EV_F05.20401.20401.2 8.19E-08 22-Dec R.LLTFMGMAVENK.E "sp|Q7L2H7|EIF3M_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 2 1352.6832 0.8 43548 20401 2 1352.678776 677.3489 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6 3791.9 - 2.10E+06 - - - -3.2927 - 2.423 0.582 - 537.1 1 2 0 -0.0045 12 0 0 0 6.87E+06 8.64E+06 - - - 5.6669 1 230117_WJC_METTL3_WT_vs_EV_F05.20402.20402.2 1.50E-06 17/30 K.IITLEEGDIILTGTPK.G sp|Q6P587|FAHD1_HUMAN 1 1711.9608 2.48 43549 20402 2 1711.952942 856.9877 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3792 - 1.70E+06 - - - -4.5714 - 3.437 0.605 - 832.5 1 2 0 -0.0078 16 0 0 0 8.61E+06 3.47E+06 - - - 6.5424 1 230117_WJC_METTL3_WT_vs_EV_F05.20403.20403.2 5.33E-06 14/24 K.LFQEDDEIPLYLK[136.11].G "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6RGV5|D6RGV5_HUMAN" 4 1629.8381 1 43550 20403 2 1629.829525 815.9263 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 3.92 3792.2 - 1.64E+06 - - - -5.2858 - 2.444 0.559 - 449.9 1 2 0 -0.0086 13 0 0 0 9.26E+06 9.24E+06 - - - 5.4606 0.9735 230117_WJC_METTL3_WT_vs_EV_F05.20404.20404.2 0.194 16-Jul K.LISLFQAMK.K "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1049.5943 2.43 43551 20404 2 1049.591892 525.8044 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.75 3792.3 - 1.52E+06 - - - -2.3304 - 1.241 0.194 - 95.8 1 2 0 -0.0024 9 0 0 0 4.06E+06 1.67E+06 - - - 1.0978 1 230117_WJC_METTL3_WT_vs_EV_F05.20405.20405.2 1.46E-07 13/26 R.WSSMEIMEAYSVAR.Q "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|Q5TG81|Q5TG81_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 5 1658.7433 1.03 43552 20405 2 1658.738519 830.3789 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 4.53 3792.5 - 1.44E+06 - - - -2.8606 - 2.612 0.67 - 587 1 2 0 -0.0047 14 0 0 0 3.49E+06 3.38E+06 - - - 6.3975 0.9937 230117_WJC_METTL3_WT_vs_EV_F05.20408.20408.2 0.000665 22-Sep K.VESLQEEIAFLK[136.11].K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1412.7642 -1 43555 20408 2 1412.758652 707.3894 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3792.8 - 1.36E+06 - - - -3.9603 - 1.925 0.403 - 249.7 1 2 0 -0.0056 12 0 0 0 0.00E+00 0.00E+00 - - - 3.739 1 230117_WJC_METTL3_WT_vs_EV_F05.20412.20412.2 0.0003 22-Nov K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.72 43558 20412 2 1317.710296 659.862 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3793.2 - 1.92E+07 - - - 0.6989 - 2.338 0.547 - 254 1 2 0 0.0009 12 0 0 0 9.92E+07 1.38E+08 - - - 5.3155 1 230117_WJC_METTL3_WT_vs_EV_F05.20413.20413.2 1.85E-08 24-Nov K.LFQEDDEIPLYLK.G "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6RGV5|D6RGV5_HUMAN" 4 1621.8239 1 43559 20413 2 1621.825224 811.9192 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 3.92 3793.2 - 2.33E+06 - - - 0.7917 - 2.294 0.586 - 336.7 1 2 0 0.0013 13 0 0 0 9.26E+06 9.24E+06 - - - 5.4998 1 230117_WJC_METTL3_WT_vs_EV_F05.20415.20415.2 0.000484 13/24 K.LILLITQVTASEK[136.11].T sp|Q15061|WDR43_HUMAN 1 1435.8741 -1 43561 20415 2 1435.869775 718.9443 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3793.4 - 0 - - - -3.0344 - 2.552 0.44 - 506 1 2 0 -0.0044 13 0 0 0 0.00E+00 0.00E+00 - - - 4.694 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.20416.20416.2 0.000172 20-Sep K.C[160.03]GPMVLDALIK.L "sp|P21912|SDHB_HUMAN,tr|A0A087WWT1|A0A087WWT1_HUMAN,tr|A0A087WXX8|A0A087WXX8_HUMAN" 3 1215.6356 -1 43562 20416 2 1215.632743 608.8251 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.83 3793.5 - 345866 - - - -2.3099 - 1.742 0.41 - 141.4 1 2 0 -0.0028 11 0 0 0 0.00E+00 0.00E+00 - - - 3.5699 0.9706 230117_WJC_METTL3_WT_vs_EV_F05.20419.20419.2 0.0894 24-Nov R.LELYAQATEALLK[136.11].T "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1469.8221 -1 43565 20419 2 1469.814559 735.9183 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 4.53 3793.9 - 0 - - - -5.1278 - 1.767 0.283 - 156.4 1 2 0 -0.0075 13 0 0 0 0.00E+00 0.00E+00 - - - 2.59 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20421.20421.2 0.000797 22-Aug K.SLLVNPVLFPNR[166.11].E sp|Q9BUB7|TMM70_HUMAN 1 1377.8008 -1 43567 20421 2 1377.803232 689.9077 "Transmembrane protein 70, mitochondrial OS=Homo sapiens OX=9606 GN=TMEM70 PE=1 SV=2" 9.47 3794.1 - 0 - - - 1.7717 - 2.028 0.374 - 194 1 2 0 0.0024 12 0 0 0 0.00E+00 0.00E+00 - - - 3.663 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.20426.20426.2 0.00175 14-Jul R.EIFNFVLK.A sp|P78527|PRKDC_HUMAN 1 1008.5644 0.75 43570 20426 2 1008.562697 505.2895 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6.1 3794.8 - 878853 - - - -1.7064 - 1.38 0.425 - 185.3 1 2 0 -0.0017 8 0 0 0 4.53E+06 6.02E+06 - - - 3.1509 1 230117_WJC_METTL3_WT_vs_EV_F05.20428.20428.3 7.49E-07 15/44 K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.75 43572 20428 3 1317.708511 440.2437 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3794.9 - 1.26E+06 - - - -0.6557 - 2.741 0.603 - 365 1 2 0 -0.0009 12 0 0 0 4.70E+06 6.30E+06 - - - 8.0575 1 230117_WJC_METTL3_WT_vs_EV_F05.20429.20429.3 1.21E-08 15/44 K.TVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1309.6952 0.75 43573 20429 3 1309.694115 437.5723 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3795 - 1.00E+06 - - - -0.8093 - 2.647 0.576 - 408.4 1 2 0 -0.0011 12 0 0 0 4.70E+06 6.30E+06 - - - 7.6597 0.9878 230117_WJC_METTL3_WT_vs_EV_F05.20431.20431.2 0.284 14-May R.EIFNFVLK[136.11].A sp|P78527|PRKDC_HUMAN 1 1016.5786 0.75 43575 20431 2 1016.581954 509.2966 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6.1 3795.2 - 651384 - - - 3.2816 - 1.158 0.208 - 79.1 2 2 0 0.0033 8 0 0 0 4.53E+06 6.02E+06 - - - 0.8842 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.20432.20432.2 0.324 16-Jul K.LLYTFPGWK[136.11].V "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1131.6208 1.89 43576 20432 2 1131.623116 566.8177 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 8.59 3795.3 - 425561 - - - 2.0316 - 1.4 0.27 - 89.1 1 2 0 0.0023 9 0 0 0 8.87E+06 4.69E+06 - - - 2.0079 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.20434.20434.2 0.00477 22-Nov R.VALDMTTLTIMR[166.11].Y "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 4 1373.7286 0.79 43578 20434 2 1373.733457 687.8716 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.81 3795.6 - 402364 - - - 3.5262 - 2.211 0.311 - 368 1 2 0 0.0048 12 0 0 0 4.48E+06 5.67E+06 - - - 3.4242 1 230117_WJC_METTL3_WT_vs_EV_F05.20435.20435.2 1.37E-09 15/26 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.61 43579 20435 2 1487.772218 744.8959 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3795.7 - 297355 - - - -3.3923 - 2.666 0.495 - 570.1 1 2 0 -0.005 14 0 0 0 2.37E+07 1.47E+07 - - - 5.1562 0.9941 230117_WJC_METTL3_WT_vs_EV_F05.20437.20437.2 8.37E-05 22-Oct R.IIPYLSFGEVEK.M "sp|Q5T4S7|UBR4_HUMAN,tr|X6R960|X6R960_HUMAN" 2 1393.7493 3.4 43581 20437 2 1393.743844 697.8819 E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1 4.53 3796 - 0 - - - -3.9283 - 1.681 0.466 - 304.7 1 2 0 -0.0055 12 0 0 0 1.74E+06 5.12E+05 - - - 3.8478 0.9918 230117_WJC_METTL3_WT_vs_EV_F05.20439.20439.2 0.00345 20-Sep K.AGFLAFTQLPK.F "sp|O75165|DJC13_HUMAN,tr|A0A3B3IRM0|A0A3B3IRM0_HUMAN" 2 1191.6652 0.43 43583 20439 2 1191.661162 596.8399 DnaJ homolog subfamily C member 13 OS=Homo sapiens OX=9606 GN=DNAJC13 PE=1 SV=5 8.8 3796.2 - 0 - - - -3.3843 - 1.718 0.316 - 161.1 1 2 0 -0.004 11 0 0 0 1.46E+06 3.37E+06 - - - 2.8377 1 230117_WJC_METTL3_WT_vs_EV_F05.20444.20444.2 1.26E-08 18/26 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.61 43586 20444 2 1487.775477 744.8959 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3796.9 - 1.73E+06 - - - -1.2018 - 2.862 0.507 - 940.3 1 2 0 -0.0018 14 0 0 0 2.37E+07 1.47E+07 - - - 5.4239 1 230117_WJC_METTL3_WT_vs_EV_F05.20446.20446.2 0.0382 15/28 K.GVYPDLLATSGDYLR.V sp|P61962|DCAF7_HUMAN 1 1638.8253 1.72 43588 20446 2 1638.8195 820.4199 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3797.2 - 1.31E+06 - - - -3.5617 - 2.756 0.568 - 524.6 1 2 0 -0.0058 15 0 0 0 6.16E+06 3.58E+06 - - - 5.7268 1 230117_WJC_METTL3_WT_vs_EV_F05.20447.20447.2 1.10E-11 16/26 R.YSALFLGVAYGATR[166.11].Y sp|P56385|ATP5I_HUMAN 1 1497.7855 1.61 43589 20447 2 1497.783207 749.9 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3797.3 - 1.13E+06 - - - -1.5543 - 2.953 0.671 - 783.2 1 2 0 -0.0023 14 0 0 0 2.37E+07 1.47E+07 - - - 6.7136 1 230117_WJC_METTL3_WT_vs_EV_F05.20449.20449.2 6.38E-09 13/28 K.GVYPDLLATSGDYLR[166.11].V sp|P61962|DCAF7_HUMAN 1 1648.8336 1.72 43591 20449 2 1648.825476 825.4241 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3797.6 - 703091 - - - -4.9314 - 2.327 0.596 - 387.3 1 2 0 -0.0081 15 0 0 0 6.16E+06 3.58E+06 - - - 5.5169 1 230117_WJC_METTL3_WT_vs_EV_F05.20450.20450.2 4.46E-07 15/22 R.VALDMTTLTIMR.Y "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 4 1363.7203 0.79 43592 20450 2 1363.716942 682.8674 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.81 3797.7 - 543116 - - - -2.4939 - 2.776 0.56 - 1008.9 1 2 0 -0.0034 12 0 0 0 4.48E+06 5.67E+06 - - - 5.8625 1 230117_WJC_METTL3_WT_vs_EV_F05.20451.20451.2 6.19E-08 18/34 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.41 43593 20451 2 1968.065048 985.0433 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3797.9 - 438539 - - - -3.5578 - 2.622 0.567 - 587.5 1 2 0 -0.007 18 0 0 0 1.66E+06 1.18E+06 - - - 5.5965 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.20452.20452.2 0.00388 20-Oct K.GVPTGFILPIR[166.11].D "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1178.7051 6.12 43594 20452 2 1178.702003 590.3598 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 3798 - 391796 - - - -2.6266 - 2.081 0.358 - 424.7 1 2 0 -0.0031 11 0 0 0 1.11E+08 1.82E+07 - - - 3.6667 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.20455.20455.2 0.000962 Dec-34 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.41 43597 20455 2 1976.084789 989.0504 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3798.4 - 250228 - - - -0.7393 - 1.968 0.489 - 267.2 1 2 0 -0.0015 18 0 0 0 1.66E+06 1.18E+06 - - - 4.3168 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20459.20459.3 0.00026 14/52 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.44 43601 20459 3 1487.775369 496.933 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3798.9 - 185963 - - - -1.2744 - 1.877 0.448 - 148.8 1 2 0 -0.0019 14 0 0 0 2.92E+06 2.02E+06 - - - 5.2076 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20461.20461.3 0.000494 14/52 R.YSALFLGVAYGATR[166.11].Y sp|P56385|ATP5I_HUMAN 1 1497.7855 1.43 43603 20461 3 1497.784694 500.2691 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3799.2 - 142119 - - - -0.5615 - 1.786 0.425 - 133.9 1 2 0 -0.0008 14 0 0 0 2.97E+06 2.07E+06 - - - 4.8194 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.20465.20465.2 0.0381 18-Aug K.VGDPVYLLGQ.- "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN" 2 1059.5601 - 43606 20465 2 1059.562302 530.7873 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 3.8 3799.5 - 2.68E+06 - - - 2.115 - 1.45 0.306 - 251.4 1 2 0 0.0022 10 0 0 0 - - - - - 2.3376 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20466.20466.2 0.00326 12-Aug R.WQFLTLR.E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 962.5338 1.36 43607 20466 2 962.534644 482.2742 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 9.75 3799.5 - 2.45E+06 - - - 0.8904 - 1.695 0.393 - 300.2 1 2 0 0.0009 7 0 0 0 5.75E+06 4.23E+06 - - - 3.6154 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20467.20467.2 8.81E-05 16-Sep R.LVSYYYFLR[166.11].F sp|Q7LGA3|HS2ST_HUMAN 1 1232.6469 0.83 43608 20467 2 1232.649437 617.3307 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 8.5 3799.6 - 1.24E+06 - - - 2.0452 - 1.596 0.452 - 273 1 2 0 0.0025 9 0 0 0 1.10E+07 1.32E+07 - - - 3.7312 1 230117_WJC_METTL3_WT_vs_EV_F05.20487.20487.2 2.08E-07 14/32 K.FLSESVLAVAGDEEVIR.F sp|Q9NWT1|PK1IP_HUMAN 1 1832.952 -1 43626 20487 2 1832.946022 917.4833 p21-activated protein kinase-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAK1IP1 PE=1 SV=2 4 3801.9 - 0 - - - -3.2581 - 3.023 0.619 - 577.7 1 2 0 -0.006 17 0 0 0 0.00E+00 0.00E+00 - - - 6.3308 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20496.20496.2 0.00138 20-Sep K.GVPTGFILPIR.D "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1168.6968 20.73 43634 20496 2 1168.697139 585.3557 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 3803 - 869091 - - - 0.2653 - 1.764 0.398 - 225.6 1 2 0 0.0003 11 0 0 0 2.13E+07 1.03E+06 - - - 3.516 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20498.20498.2 4.58E-05 16-Oct K.C[160.03]MPTFQFFK.K sp|P10599|THIO_HUMAN 1 1204.5409 3.17 43635 20498 2 1204.54153 603.2777 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3803.2 - 2.06E+06 - - - 0.5039 - 1.581 0.517 - 234.3 1 2 0 0.0006 9 0 0 0 2.78E+07 8.76E+06 - - - 4.1846 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.20500.20500.2 0.98 14-Aug R.VLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 881.6062 1.32 43637 20500 2 881.604801 441.8104 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3803.4 - 1.11E+07 - - - -1.613 - 1.724 0.351 - 212.2 1 2 0 -0.0014 8 0 0 0 6.10E+07 4.63E+07 - - - 3.2757 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.20501.20501.2 0.356 14-Sep R.VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 891.6145 1.32 43638 20501 2 891.612932 446.8145 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3803.5 - 9.01E+06 - - - -1.7508 - 1.949 0.262 - 358.1 1 2 0 -0.0016 8 0 0 0 6.10E+07 4.63E+07 - - - 2.9882 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.20503.20503.2 1.59E-06 20-Dec K.GIFNGFSVTLK.E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1181.6445 1.84 43640 20503 2 1181.642185 591.8295 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3803.7 - 5.15E+06 - - - -1.9244 - 2.281 0.441 - 369.2 1 2 0 -0.0023 11 0 0 0 1.78E+07 9.65E+06 - - - 4.5283 0.9932 230117_WJC_METTL3_WT_vs_EV_F05.20505.20505.2 0.00423 16-Sep R.FTGLESIFR[166.11].A sp|Q8N4Q0|PTGR3_HUMAN 1 1078.5687 0.81 43642 20505 2 1078.564418 540.2916 Prostaglandin reductase 3 OS=Homo sapiens OX=9606 GN=ZADH2 PE=1 SV=1 6 3803.9 - 2.69E+06 - - - -3.9376 - 1.706 0.408 - 223.4 1 2 0 -0.0042 9 0 0 0 5.37E+07 6.65E+07 - - - 3.5985 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20507.20507.2 0.00605 18-Oct K.VLEAELLVLR[166.11].Q sp|P07196|NFL_HUMAN 1 1163.7153 0.87 43644 20507 2 1163.716452 582.8649 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.53 3804.2 - 1.72E+06 - - - 0.9642 - 1.985 0.354 - 273.3 1 2 0 0.0011 10 0 0 0 5.00E+06 5.75E+06 - - - 3.5691 0.9952 230117_WJC_METTL3_WT_vs_EV_F05.20508.20508.2 0.0566 16-Oct K.IQLPIIQLR.K sp|O15111|IKKA_HUMAN 1 1092.7019 2.87 43645 20508 2 1092.699015 547.3582 Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Homo sapiens OX=9606 GN=CHUK PE=1 SV=2 9.75 3804.3 - 1.35E+06 - - - -2.654 - 1.947 0.267 - 325.6 1 2 0 -0.0029 9 0 0 0 5.70E+06 1.99E+06 - - - 2.9398 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.20509.20509.2 0.0139 16-Aug R.LVFGFLNGR.A "sp|P00491|PNPH_HUMAN,tr|G3V2H3|G3V2H3_HUMAN,tr|G3V5M2|G3V5M2_HUMAN" 3 1021.5709 4.44 43646 20509 2 1021.570255 511.7927 Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2 9.75 3804.4 - 1.25E+06 - - - -0.6324 - 1.334 0.394 - 229.3 1 2 0 -0.0006 9 0 0 0 6.08E+06 1.37E+06 - - - 2.7846 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20510.20510.2 0.00569 20-Nov R.LLGAALPLLTK.E "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1108.722 0.89 43647 20510 2 1108.721527 555.3683 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 8.75 3804.6 - 1.24E+06 - - - -0.4104 - 1.74 0.434 - 189.7 1 2 0 -0.0005 11 0 0 0 8.61E+06 9.68E+06 - - - 3.7448 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.20511.20511.2 0.00151 20-Oct R.LLGAALPLLTK[136.11].E "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1116.7362 0.89 43648 20511 2 1116.734928 559.3754 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 8.75 3804.7 - 1.23E+06 - - - -1.1229 - 1.999 0.319 - 164.1 1 2 0 -0.0013 11 0 0 0 8.63E+06 9.68E+06 - - - 3.2705 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.20513.20513.2 0.000394 16-Sep K.C[160.03]MPTFQFFK[136.11].K sp|P10599|THIO_HUMAN 1 1212.5551 3.17 43650 20513 2 1212.552267 607.2848 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3804.9 - 1.05E+06 - - - -2.3554 - 1.412 0.423 - 169.2 1 2 0 -0.0029 9 0 0 0 2.78E+07 8.76E+06 - - - 3.1625 0.997 230117_WJC_METTL3_WT_vs_EV_F05.20515.20515.2 0.0971 16-Jul K.DLSDFPLIK.K "sp|P20585|MSH3_HUMAN,tr|A0A590UJN8|A0A590UJN8_HUMAN,tr|A0A590UKC9|A0A590UKC9_HUMAN,tr|A0A590UJW0|A0A590UJW0_HUMAN" 4 1046.5648 1.96 43652 20515 2 1046.564421 524.2897 DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4 4.21 3805.2 - 902800 - - - -0.3736 - 1.277 0.291 - 124.5 1 2 0 -0.0004 9 0 0 0 3.91E+06 2.00E+06 - - - 1.8976 0.9971 230117_WJC_METTL3_WT_vs_EV_F05.20517.20517.2 0.0599 20-Aug K.FMELLEPLNER[166.11].K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1399.7045 0.78 43654 20517 2 1399.701873 700.8595 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.25 3805.5 - 807766 - - - -1.8818 - 1.614 0.356 - 166.1 1 2 0 -0.0026 11 0 0 0 3.06E+06 3.92E+06 - - - 2.9646 0.9863 230117_WJC_METTL3_WT_vs_EV_F05.20520.20520.2 0.306 14-Jun K.VFLDVLMK[136.11].E sp|Q14684|RRP1B_HUMAN 1 971.5605 -1 43656 20520 2 971.559929 486.7875 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.81 3805.8 - 848906 - - - -0.6134 - 1.072 0.207 - 102.6 1 2 0 -0.0006 8 0 0 0 0.00E+00 0.00E+00 - - - 0.7794 0.9948 230117_WJC_METTL3_WT_vs_EV_F05.20521.20521.2 0.918 14-Jul K.DTLGLFLR.E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 933.5284 1.46 43657 20521 2 933.527446 467.7715 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.84 3805.9 - 2.96E+07 - - - -0.9866 - 1.502 0.2 - 217.8 1 2 0 -0.0009 8 0 0 0 9.79E+07 6.69E+07 - - - 1.7448 1 230117_WJC_METTL3_WT_vs_EV_F05.20523.20523.2 0.00956 13/18 K.MAEMLVELVR.R sp|Q9Y605|MOFA1_HUMAN 1 1189.6199 1.36 43659 20523 2 1189.615149 595.8172 MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1 4.53 3806 - 1.40E+07 - - - -3.9946 - 2.652 0.513 - 1027.3 1 2 0 -0.0048 10 0 0 0 3.23E+07 2.38E+07 - - - 5.5509 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.20524.20524.2 0.000806 18-Oct R.IYLDMLNVYK.C "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 11 1270.6631 1.59 43660 20524 2 1270.660494 636.3388 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.83 3806 - 1.08E+07 - - - -2.0871 - 2.012 0.459 - 320.3 1 2 0 -0.0027 10 0 0 0 3.32E+07 2.09E+07 - - - 4.3818 1 230117_WJC_METTL3_WT_vs_EV_F05.20525.20525.2 7.26E-07 16/24 K.ILESSQTLLSVLK.R "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1429.8392 3.04 43661 20525 2 1429.837634 715.9269 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 6 3806.1 - 1.05E+07 - - - -1.0924 - 2.871 0.586 - 686.5 1 2 0 -0.0016 13 0 0 0 4.53E+07 1.49E+07 - - - 6.0755 1 230117_WJC_METTL3_WT_vs_EV_F05.20527.20527.2 1.79E-10 15/30 R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 11.1 43663 20527 2 1756.902377 879.4608 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3806.3 - 4.69E+06 - - - -2.6074 - 3.383 0.547 - 797.2 1 2 0 -0.0046 16 0 0 0 5.14E+07 4.63E+06 - - - 6.0761 1 230117_WJC_METTL3_WT_vs_EV_F05.20528.20528.2 1.62E-05 26-Nov K.VTVNPGLLVPLDVK.L sp|Q6KB66|K2C80_HUMAN 1 1462.8759 -1 43664 20528 2 1462.874832 732.4452 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 5.81 3806.4 - 3.88E+06 - - - -0.741 - 2.339 0.531 - 332.5 1 2 0 -0.0011 14 0 0 0 0.00E+00 0.00E+00 - - - 5.095 1 230117_WJC_METTL3_WT_vs_EV_F05.20529.20529.2 0.000535 16/26 K.IPVTIITGYLGAGK.T "sp|Q5RIA9|CBWD5_HUMAN,sp|Q9BRT8|CBWD1_HUMAN,sp|Q5JTY5|CBWD3_HUMAN,sp|Q4V339|CBWD6_HUMAN,sp|Q8IUF1|CBWD2_HUMAN,tr|A0A087WZQ3|A0A087WZQ3_HUMAN,tr|Q5JTY2|Q5JTY2_HUMAN,tr|Q6NVZ8|Q6NVZ8_HUMAN,tr|A0A0B4J2E3|A0A0B4J2E3_HUMAN,tr|A0A087X140|A0A087X140_HUMAN,tr|F8WEU0|F8WEU0_HUMAN,tr|E7EUZ7|E7EUZ7_HUMAN,tr|F8WEG4|F8WEG4_HUMAN,tr|A0A087WYD2|A0A087WYD2_HUMAN,tr|A0A0A0MRU4|A0A0A0MRU4_HUMAN,tr|Q5RIB0|Q5RIB0_HUMAN,tr|H0Y5V3|H0Y5V3_HUMAN,tr|A0A0A6YYH9|A0A0A6YYH9_HUMAN,tr|A0A087WWG3|A0A087WWG3_HUMAN,tr|A0A087WTC0|A0A087WTC0_HUMAN,tr|C9J3G2|C9J3G2_HUMAN,tr|F2Z2T4|F2Z2T4_HUMAN,tr|Q5RIB5|Q5RIB5_HUMAN" 23 1401.8232 4.08 43665 20529 2 1401.820826 701.9189 COBW domain-containing protein 5 OS=Homo sapiens OX=9606 GN=CBWD5 PE=2 SV=1 8.59 3806.5 - 2.90E+06 - - - -1.6593 - 3.119 0.482 - 997.2 1 2 0 -0.0023 14 0 0 0 8.26E+06 2.03E+06 - - - 5.4549 0.999 230117_WJC_METTL3_WT_vs_EV_F05.20532.20532.2 7.35E-05 22-Nov R.VIQELLVDYYVK.L "sp|Q9H6D7|HAUS4_HUMAN,tr|H0YJ09|H0YJ09_HUMAN,tr|G3V4X7|G3V4X7_HUMAN,tr|G3V5A5|G3V5A5_HUMAN,tr|G3V541|G3V541_HUMAN,tr|H0YIZ6|H0YIZ6_HUMAN,tr|G3V5Z2|G3V5Z2_HUMAN" 7 1480.8177 -1 43668 20532 2 1480.815528 741.4161 HAUS augmin-like complex subunit 4 OS=Homo sapiens OX=9606 GN=HAUS4 PE=1 SV=1 4.37 3806.9 - 2.10E+06 - - - -1.489 - 2.153 0.439 - 436.5 1 2 0 -0.0022 12 0 0 0 0.00E+00 0.00E+00 - - - 4.3005 0.9524 230117_WJC_METTL3_WT_vs_EV_F05.20534.20534.2 0.623 12-Jun K.DLVEWLK.L "sp|Q9P2D1|CHD7_HUMAN,sp|Q14554|PDIA5_HUMAN" 2 901.4909 1.87 43670 20534 2 901.488687 451.7527 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.37 3807.2 - 1.67E+06 - - - -2.4759 - 1.384 0.087 - 113.9 1 2 0 -0.0022 7 0 0 0 7.14E+06 3.82E+06 - - - 0.7126 0.9892 230117_WJC_METTL3_WT_vs_EV_F05.20536.20536.2 0.196 28-Jul K.VLVIGAGGLGC[160.03]ELLK.N "sp|Q8TBC4|UBA3_HUMAN,tr|F8WF86|F8WF86_HUMAN" 2 1497.8589 -1 43672 20536 2 1497.859769 749.9367 NEDD8-activating enzyme E1 catalytic subunit OS=Homo sapiens OX=9606 GN=UBA3 PE=1 SV=2 5.97 3807.5 - 1.29E+06 - - - 0.5895 - 1.165 0.148 - 91.5 1 2 0 0.0009 15 0 0 0 0.00E+00 0.00E+00 - - - 0.5093 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.20542.20542.3 0.000382 Oct-60 R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 8.46 43677 20542 3 1756.905729 586.6429 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3808 - 1.41E+07 - - - -0.6995 - 2.13 0.426 - 162.9 1 2 0 -0.0012 16 0 0 0 3.27E+07 3.87E+06 - - - 5.2292 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.20543.20543.2 0.0255 22-Oct K.IGLIQFC[160.03]LSAPK.T sp|P50991|TCPD_HUMAN 1 1345.7428 8.7 43678 20543 2 1345.742586 673.8787 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3808.1 - 1.30E+07 - - - -0.1546 - 1.34 0.275 - 157.3 1 2 0 -0.0002 12 0 0 0 6.11E+07 7.02E+06 - - - 1.8421 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.20544.20544.2 0.00235 18-Aug K.DLIGVQNLLK[136.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1119.6743 0.91 43679 20544 2 1119.673303 560.8444 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3808.1 - 7.72E+06 - - - -0.8994 - 1.799 0.436 - 162.1 1 2 0 -0.001 10 0 0 0 1.44E+07 1.58E+07 - - - 3.9001 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.20545.20545.2 0.00589 18-Sep K.DLIGVQNLLK.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1111.6601 0.91 43680 20545 2 1111.659597 556.8373 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3808.2 - 7.14E+06 - - - -0.4615 - 1.849 0.347 - 187.5 1 2 0 -0.0005 10 0 0 0 1.44E+07 1.58E+07 - - - 3.3194 1 230117_WJC_METTL3_WT_vs_EV_F05.20546.20546.2 3.10E-06 16/28 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 -1 43681 20546 2 1548.92386 775.4692 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3808.3 - 4.04E+06 - - - -0.0445 - 3.067 0.615 - 602.9 1 2 0 -0.0001 15 0 0 0 0.00E+00 0.00E+00 - - - 6.3387 1 230117_WJC_METTL3_WT_vs_EV_F05.20549.20549.2 1.02E-06 16/28 K.LLGASELPIVTPALR[166.11].A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1558.9322 -1 43684 20549 2 1558.932296 780.4734 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3808.7 - 3.06E+06 - - - 0.0622 - 3.304 0.583 - 506.6 1 2 0 0.0001 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2853 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.20551.20551.2 0.0233 16-Oct R.NALDLLLPK.L "sp|P30566|PUR8_HUMAN,tr|A0A096LNY5|A0A096LNY5_HUMAN,tr|A0A1B0GTJ7|A0A1B0GTJ7_HUMAN,tr|A0A1B0GWJ0|A0A1B0GWJ0_HUMAN,tr|A0A1B0GWF8|A0A1B0GWF8_HUMAN,tr|A0A096LNY4|A0A096LNY4_HUMAN,tr|A0A1B0GTG9|A0A1B0GTG9_HUMAN,tr|A0A7P0T9A7|A0A7P0T9A7_HUMAN,tr|A0A096LNY6|A0A096LNY6_HUMAN,tr|A0A096LP92|A0A096LP92_HUMAN,tr|A0A7P0Z472|A0A7P0Z472_HUMAN" 11 995.6015 1.75 43686 20551 2 995.600534 498.808 Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2 5.84 3808.9 - 2.65E+06 - - - -1.0024 - 1.844 0.343 - 350.4 1 2 0 -0.001 9 0 0 0 6.82E+06 3.89E+06 - - - 3.3445 1 230117_WJC_METTL3_WT_vs_EV_F05.20552.20552.2 0.000101 14/20 K.WYLENVYPELR.V sp|Q10471|GALT2_HUMAN 1 1480.7351 -1 43687 20552 2 1480.738595 741.3748 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3809 - 2.61E+06 - - - 2.384 - 2.418 0.494 - 754.6 1 2 0 0.0035 11 0 0 0 0.00E+00 0.00E+00 - - - 5.0771 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.20553.20553.2 0.056 24-Jun K.MLVLDEADEMLNK.G "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1519.7262 -1 43688 20553 2 1519.727127 760.8704 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 3.92 3809.1 - 2.25E+06 - - - 0.5988 - 1.31 0.29 - 50.5 1 2 0 0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 1.8757 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20554.20554.2 0.000105 18-Aug K.IMLPWDPTGK.L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1156.5951 1.9 43689 20554 2 1156.594227 579.3048 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3809.2 - 2.19E+06 - - - -0.7254 - 1.572 0.501 - 248.3 1 2 0 -0.0008 10 0 0 0 3.18E+07 1.67E+07 - - - 4.0038 1 230117_WJC_METTL3_WT_vs_EV_F05.20555.20555.2 1.44E-10 16/30 R.LMNETTAVALAYGIYK[136.11].Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1764.9212 -1 43690 20555 2 1764.918576 883.4679 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3809.3 - 2.06E+06 - - - -1.463 - 3.31 0.625 - 1018.8 1 2 0 -0.0026 16 0 0 0 0.00E+00 0.00E+00 - - - 6.5992 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.20557.20557.2 0.0232 18-Aug R.VMEVFLAQLR[166.11].L sp|Q96S52|PIGS_HUMAN 1 1214.6721 -1 43692 20557 2 1214.671232 608.3433 GPI transamidase component PIG-S OS=Homo sapiens OX=9606 GN=PIGS PE=1 SV=3 5.97 3809.6 - 1.79E+06 - - - -0.7022 - 1.479 0.346 - 125.9 1 2 0 -0.0009 10 0 0 0 0.00E+00 0.00E+00 - - - 2.6887 1 230117_WJC_METTL3_WT_vs_EV_F05.20558.20558.2 9.38E-05 14/22 K.IGLIQFC[160.03]LSAPK[136.11].T sp|P50991|TCPD_HUMAN 1 1353.757 8.71 43693 20558 2 1353.761433 677.8858 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3809.7 - 1.64E+06 - - - 3.279 - 2.787 0.498 - 886 1 2 0 0.0044 12 0 0 0 6.12E+07 7.02E+06 - - - 5.4147 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.20561.20561.2 0.00208 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 4905.57 43695 20561 2 1603.763744 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3810 - 4.06E+08 - - - -0.1222 - 1.53 0.46 - 192.9 1 2 0 -0.0002 12 0 0 0 4.79E+09 9.76E+05 - - - 3.5575 1 230117_WJC_METTL3_WT_vs_EV_F05.20563.20563.2 1.19E-05 18-Sep R.AFDLFNPNFK.S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1211.5975 1.37 43697 20563 2 1211.595833 606.806 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3810.2 - 5.07E+06 - - - -1.3833 - 1.957 0.536 - 257.6 1 2 0 -0.0017 10 0 0 0 1.18E+07 8.58E+06 - - - 4.8735 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.20565.20565.2 0.000329 18-Dec K.IMLPWDPTGK[136.11].L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1164.6093 1.93 43699 20565 2 1164.60786 583.3119 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3810.4 - 2.74E+06 - - - -1.2073 - 2.013 0.451 - 535.1 1 2 0 -0.0014 10 0 0 0 3.18E+07 1.64E+07 - - - 4.3245 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.20566.20566.2 0.713 12-Jul R.EIALWFR[166.11].A "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 943.5155 -1 43700 20566 2 943.5154 472.765 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6.1 3810.4 - 2.66E+06 - - - -0.1145 - 1.625 0.234 - 203.1 2 2 0 -0.0001 7 0 0 0 0.00E+00 0.00E+00 - - - 2.1732 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.20567.20567.2 0.000234 18-Oct R.ISYSLFTALR[166.11].V "sp|Q53GQ0|DHB12_HUMAN,tr|E9PI21|E9PI21_HUMAN,tr|A0A1B0GW85|A0A1B0GW85_HUMAN,tr|A0A1B0GU83|A0A1B0GU83_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN" 5 1179.6527 -1 43701 20567 2 1179.650978 590.8336 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 8.75 3810.6 - 1.74E+06 - - - -1.4843 - 2.015 0.395 - 283.6 1 2 0 -0.0018 10 0 0 0 0.00E+00 0.00E+00 - - - 3.9136 0.9638 230117_WJC_METTL3_WT_vs_EV_F05.20568.20568.2 0.00095 16-Aug R.FVC[160.03]PVILFK[136.11].G "sp|Q8NCE2|MTMRE_HUMAN,tr|B4DJ23|B4DJ23_HUMAN" 2 1129.6449 0.81 43702 20568 2 1129.638493 565.8297 Myotubularin-related protein 14 OS=Homo sapiens OX=9606 GN=MTMR14 PE=1 SV=2 8.22 3810.7 - 1.66E+06 - - - -5.6929 - 1.528 0.336 - 172.5 1 2 0 -0.0064 9 0 0 0 2.88E+06 3.57E+06 - - - 2.7472 0.9851 230117_WJC_METTL3_WT_vs_EV_F05.20569.20569.2 0.198 18-Nov K.QLLLIAGLTR.E "sp|Q9UJX2|CDC23_HUMAN,tr|D6RCF8|D6RCF8_HUMAN,tr|D6RBY8|D6RBY8_HUMAN,tr|H0Y936|H0Y936_HUMAN" 4 1096.6968 0.46 43703 20569 2 1096.694691 549.3557 Cell division cycle protein 23 homolog OS=Homo sapiens OX=9606 GN=CDC23 PE=1 SV=3 9.75 3810.8 - 1.59E+06 - - - -1.9495 - 1.923 0.068 - 300.4 1 2 0 -0.0021 10 0 0 0 4.73E+06 1.02E+07 - - - 1.3678 1 230117_WJC_METTL3_WT_vs_EV_F05.20570.20570.2 1.97E-06 22-Dec K.GIDPFSLDALSK.E sp|P40227|TCPZ_HUMAN 1 1261.6554 10.24 43704 20570 2 1261.651239 631.835 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3811 - 1.30E+06 - - - -3.3123 - 2.396 0.565 - 385.4 1 2 0 -0.0042 12 0 0 0 2.26E+08 2.21E+07 - - - 5.5119 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20571.20571.2 0.0171 14-Jul K.FGFYEVFK[136.11].V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1043.5208 1.09 43705 20571 2 1043.520699 522.7677 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3811.1 - 1.25E+06 - - - -0.0671 - 1.61 0.381 - 104 1 2 0 -0.0001 8 0 0 0 1.28E+07 1.18E+07 - - - 3.2913 1 230117_WJC_METTL3_WT_vs_EV_F05.20572.20572.2 0.000326 13/22 R.LAGATLLIFANK.Q sp|P36404|ARL2_HUMAN 1 1230.7336 -1 43706 20572 2 1230.731202 616.3741 ADP-ribosylation factor-like protein 2 OS=Homo sapiens OX=9606 GN=ARL2 PE=1 SV=4 8.75 3811.2 - 1.01E+06 - - - -1.9557 - 2.383 0.485 - 431.3 1 2 0 -0.0024 12 0 0 0 0.00E+00 0.00E+00 - - - 4.9073 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.20573.20573.2 0.0062 14-Aug R.ETILNLLR[166.11].K "sp|Q6P158|DHX57_HUMAN,tr|A0A087WZ11|A0A087WZ11_HUMAN" 2 980.5894 0.75 43707 20573 2 980.58757 491.302 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 6.1 3811.4 - 917225 - - - -1.8672 - 1.881 0.332 - 229.5 1 2 0 -0.0018 8 0 0 0 1.64E+06 2.18E+06 - - - 3.3981 0.9956 230117_WJC_METTL3_WT_vs_EV_F05.20577.20577.2 0.282 14-Jul R.ETILNLLR.K "sp|Q6P158|DHX57_HUMAN,tr|A0A087WZ11|A0A087WZ11_HUMAN" 2 970.5811 0.75 43711 20577 2 970.579771 486.2978 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 6.1 3811.9 - 667023 - - - -1.4012 - 1.727 0.199 - 180.3 1 2 0 -0.0014 8 0 0 0 1.64E+06 2.18E+06 - - - 2.1583 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.20580.20580.2 0.00921 22-Sep K.LVGQSIIAYLQK.K "sp|P53621|COPA_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 3 1331.7813 2.99 43714 20580 2 1331.780174 666.8979 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 8.59 3812.3 - 549597 - - - -0.8357 - 1.535 0.39 - 204.1 1 2 0 -0.0011 12 0 0 0 1.17E+06 3.90E+05 - - - 3.0487 1 230117_WJC_METTL3_WT_vs_EV_F05.20582.20582.3 9.72E-08 19/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 43715 20582 3 1603.766312 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3812.5 - 2.00E+07 - - - 1.479 - 2.977 0.596 - 547.6 1 2 0 0.0024 12 0 0 0 6.54E+08 0.00E+00 - - - 8.208 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20584.20584.2 0.00359 14-Sep K.FGFYEVFK.V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1035.5066 1.06 43717 20584 2 1035.506876 518.7606 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3812.7 - 2.18E+06 - - - 0.2965 - 1.735 0.412 - 185.6 1 2 0 0.0003 8 0 0 0 1.25E+07 1.18E+07 - - - 3.7457 1 230117_WJC_METTL3_WT_vs_EV_F05.20588.20588.2 0.000114 22-Dec K.GIDPFSLDALSK[136.11].E sp|P40227|TCPZ_HUMAN 1 1269.6696 10.24 43721 20588 2 1269.669697 635.8421 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3813.2 - 540965 - - - 0.0622 - 2.448 0.561 - 398.7 1 2 0 0.0001 12 0 0 0 2.26E+08 2.21E+07 - - - 5.5401 1 230117_WJC_METTL3_WT_vs_EV_F05.20590.20590.2 0.00364 17/22 R.VPFLVLEC[160.03]PNLK.L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1427.7847 1.02 43723 20590 2 1427.78336 714.8996 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3813.5 - 501298 - - - -0.9091 - 2.86 0.525 - 1387.8 1 2 0 -0.0013 12 0 0 0 5.22E+06 5.10E+06 - - - 5.6831 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20594.20594.2 0.000114 18-Oct K.FSDFLLDPYK[136.11].Y sp|Q9UIG0|BAZ1B_HUMAN 1 1251.6267 1.09 43727 20594 2 1251.628205 626.8206 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 4.21 3814 - 348921 - - - 1.2096 - 2.14 0.309 - 264.9 1 2 0 0.0015 10 0 0 0 5.45E+06 4.98E+06 - - - 3.4464 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.20605.20605.2 0.0216 16-Sep K.TEILPPFFK.H sp|O75533|SF3B1_HUMAN 1 1090.6063 1.09 43737 20605 2 1090.60591 546.3104 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.66 3815.3 - 347357 - - - -0.342 - 1.488 0.339 - 321.6 1 2 0 -0.0004 9 0 0 0 5.47E+07 5.00E+07 - - - 2.6945 0.9946 230117_WJC_METTL3_WT_vs_EV_F05.20608.20608.2 0.296 16-Aug K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 5966.89 43738 20608 2 1014.538647 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3815.7 - 1.07E+07 - - - 4.0137 - 1.551 0.225 - 124.1 1 2 0 0.0041 9 0 0 0 2.30E+08 3.85E+04 - - - 1.9713 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.20609.20609.2 1.12 16-Sep K.TEILPPFFK[136.11].H sp|O75533|SF3B1_HUMAN 1 1098.6205 1.09 43739 20609 2 1098.620012 550.3175 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.66 3815.8 - 2.02E+06 - - - -0.4287 - 1.794 0.256 - 341.3 1 2 0 -0.0005 9 0 0 0 5.47E+07 5.00E+07 - - - 2.6225 1 230117_WJC_METTL3_WT_vs_EV_F05.20611.20611.2 1.09E-05 16-Oct R.FYNLVLLPR[166.11].V "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1143.668 1.16 43741 20611 2 1143.668958 572.8413 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 3816.1 - 1.46E+06 - - - 0.8499 - 2.138 0.581 - 446.6 1 2 0 0.001 9 0 0 0 3.48E+07 3.00E+07 - - - 5.5303 1 230117_WJC_METTL3_WT_vs_EV_F05.20612.20612.2 5.63E-08 15/20 K.WYLENVYPELR[166.11].V sp|Q10471|GALT2_HUMAN 1 1490.7433 1.05 43742 20612 2 1490.744854 746.3789 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3816.2 - 1.40E+06 - - - 1.019 - 2.566 0.425 - 1016.3 1 2 0 0.0015 11 0 0 0 7.44E+06 7.07E+06 - - - 4.7288 1 230117_WJC_METTL3_WT_vs_EV_F05.20613.20613.2 3.42E-05 16-Oct R.FYNLVLLPR.V "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1133.6597 1.16 43743 20613 2 1133.660589 567.8371 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 3816.4 - 1.26E+06 - - - 0.7701 - 2.032 0.482 - 413.8 1 2 0 0.0009 9 0 0 0 3.48E+07 3.00E+07 - - - 4.652 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20614.20614.2 0.000884 20-Nov R.NTISLLVAGLK.K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1127.6914 1.63 43744 20614 2 1127.692158 564.853 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.75 3816.5 - 953400 - - - 0.6633 - 2.32 0.405 - 467.1 1 2 0 0.0007 11 0 0 0 6.01E+06 3.70E+06 - - - 4.3087 1 230117_WJC_METTL3_WT_vs_EV_F05.20615.20615.2 0.00016 13/22 R.VPFLVLEC[160.03]PNLK[136.11].L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1435.7989 1.02 43745 20615 2 1435.799698 718.9067 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3816.6 - 953392 - - - 0.585 - 2.378 0.488 - 582.1 1 2 0 0.0008 12 0 0 0 5.22E+06 5.10E+06 - - - 4.9244 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20616.20616.2 0.0175 20-Oct K.FLFVDADQIVR.T sp|Q9NYU2|UGGG1_HUMAN 1 1321.703 8.64 43746 20616 2 1321.703462 661.8588 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.21 3816.7 - 921456 - - - 0.3216 - 2.065 0.395 - 315.4 1 2 0 0.0004 11 0 0 0 3.68E+07 4.26E+06 - - - 3.92 1 230117_WJC_METTL3_WT_vs_EV_F05.20617.20617.2 0.00152 13/20 K.ILLTQENPFFR[166.11].K sp|Q08J23|NSUN2_HUMAN 1 1386.7535 2.27 43747 20617 2 1386.754057 694.384 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3816.9 - 638294 - - - 0.3973 - 2.666 0.484 - 701.9 1 2 0 0.0006 11 0 0 0 8.00E+07 3.53E+07 - - - 5.2683 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20619.20619.2 0.000172 18-Oct K.YSDIDIILLK[136.11].G "sp|Q92973|TNPO1_HUMAN,tr|A0A7P0T9C0|A0A7P0T9C0_HUMAN,tr|A0A7P0TBF0|A0A7P0TBF0_HUMAN,tr|A0A7P0T944|A0A7P0T944_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 5 1199.6893 1.09 43749 20619 2 1199.688757 600.8519 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 4.21 3817.1 - 540274 - - - -0.4451 - 1.835 0.405 - 202.2 1 2 0 -0.0005 10 0 0 0 1.21E+07 1.11E+07 - - - 3.7266 0.9926 230117_WJC_METTL3_WT_vs_EV_F05.20620.20620.2 0.223 16-Aug R.NALDLLLPK[136.11].L "sp|P30566|PUR8_HUMAN,tr|A0A096LNY5|A0A096LNY5_HUMAN,tr|A0A1B0GTJ7|A0A1B0GTJ7_HUMAN,tr|A0A1B0GWJ0|A0A1B0GWJ0_HUMAN,tr|A0A1B0GWF8|A0A1B0GWF8_HUMAN,tr|A0A096LNY4|A0A096LNY4_HUMAN,tr|A0A1B0GTG9|A0A1B0GTG9_HUMAN,tr|A0A7P0T9A7|A0A7P0T9A7_HUMAN,tr|A0A096LNY6|A0A096LNY6_HUMAN,tr|A0A096LP92|A0A096LP92_HUMAN,tr|A0A7P0Z472|A0A7P0Z472_HUMAN" 11 1003.6157 1.38 43750 20620 2 1003.616014 502.8151 Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2 5.84 3817.3 - 535835 - - - 0.281 - 1.408 0.113 - 146.7 1 2 0 0.0003 9 0 0 0 6.60E+06 4.77E+06 - - - 0.8654 0.9437 230117_WJC_METTL3_WT_vs_EV_F05.20624.20624.2 0.0335 22-Dec R.FLPEFPSC[160.03]SLLK[136.11].E sp|Q9H9A6|LRC40_HUMAN 1 1444.7516 2.12 43754 20624 2 1444.747916 723.3831 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.99 3817.8 - 300462 - - - -2.5319 - 1.412 0.09 - 183.7 1 2 0 -0.0037 12 0 0 0 5.93E+06 2.79E+06 - - - 0.6124 1 230117_WJC_METTL3_WT_vs_EV_F05.20625.20625.2 7.94E-06 13/24 K.ILGVWDTAVSLGK.L sp|Q53RT3|APRV1_HUMAN 1 1357.7606 999 43755 20625 2 1357.759303 679.8876 Retroviral-like aspartic protease 1 OS=Homo sapiens OX=9606 GN=ASPRV1 PE=1 SV=1 5.84 3817.9 - 265403 - - - -0.9199 - 2.53 0.5 - 530.8 1 2 0 -0.0012 13 0 0 0 1.07E+07 0.00E+00 - - - 5.1159 1 230117_WJC_METTL3_WT_vs_EV_F05.20631.20631.2 1.06E-07 16/22 R.VPDGMVGLIIGR.G "sp|Q92945|FUBP2_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 1225.6853 2.16 43760 20631 2 1225.687438 613.8499 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.81 3818.6 - 2.32E+06 - - - 1.7623 - 2.661 0.609 - 1132.6 1 2 0 0.0022 12 0 0 0 2.49E+07 1.15E+07 - - - 6.1135 1 230117_WJC_METTL3_WT_vs_EV_F05.20632.20632.2 7.17E-07 18/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 43761 20632 2 1343.610843 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3818.8 - 1.45E+06 - - - -0.4607 - 3.015 0.531 - 1259.5 1 1 0 -0.0006 10 0 0 0 2.76E+07 0.00E+00 - - - 6.0433 1 230117_WJC_METTL3_WT_vs_EV_F05.20633.20633.3 9.56E-06 18/56 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.38 43762 20633 3 1548.92482 517.3153 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3818.9 - 1.15E+06 - - - 0.5752 - 2.637 0.545 - 570.3 1 2 0 0.0009 15 0 0 0 6.14E+06 4.45E+06 - - - 7.1461 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.20635.20635.2 0.00715 14-Jul K.DLEDLFYK.Y "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1041.5019 1.31 43764 20635 2 1041.501695 521.7582 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.03 3819.2 - 909506 - - - -0.1757 - 1.452 0.295 - 159.3 1 2 0 -0.0002 8 0 0 0 7.49E+06 5.73E+06 - - - 2.3446 1 230117_WJC_METTL3_WT_vs_EV_F05.20640.20640.2 0.00101 22-Nov R.YGLFPANYVELR[166.11].Q sp|Q14247|SRC8_HUMAN 1 1450.7484 2.04 43769 20640 2 1450.74856 726.3815 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 6 3819.8 - 312455 - - - 0.0958 - 2.028 0.55 - 397.4 1 2 0 0.0001 12 0 0 0 1.51E+07 7.39E+06 - - - 4.9636 1 230117_WJC_METTL3_WT_vs_EV_F05.20641.20641.2 1.14E-07 15/28 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 1077.04 43770 20641 2 1658.909468 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3820 - 311598 - - - 0.2417 - 3.073 0.531 - 824.6 1 2 0 0.0004 15 0 0 0 2.74E+08 2.55E+05 - - - 5.7229 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20644.20644.2 0.0728 13/18 K.ILDVLEEIPK[136.11].N "sp|Q16718|NDUA5_HUMAN,tr|C9IZN5|C9IZN5_HUMAN,tr|H7BYD0|H7BYD0_HUMAN,tr|A0A087X1G1|A0A087X1G1_HUMAN,tr|F8WAS3|F8WAS3_HUMAN,tr|A0A7I2V2W4|A0A7I2V2W4_HUMAN,tr|A0A7I2V3L8|A0A7I2V3L8_HUMAN" 7 1175.6893 2.67 43772 20644 2 1175.689078 588.8519 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3 4.14 3820.4 - 2.25E+06 - - - -0.1812 - 2.305 0.345 - 384.8 1 2 0 -0.0002 10 0 0 0 3.06E+07 1.14E+07 - - - 3.9201 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.20646.20646.2 0.000125 20-Sep K.LFTAESLIGLK.N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1190.6911 1.9 43773 20646 2 1190.689245 596.3528 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6 3820.7 - 1.81E+06 - - - -1.5369 - 1.864 0.426 - 203.1 1 2 0 -0.0018 11 0 0 0 4.25E+07 2.23E+07 - - - 3.8715 0.8833 230117_WJC_METTL3_WT_vs_EV_F05.20647.20647.2 0.00641 20-Dec K.LTPLILKPFGN.S "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1211.7278 0.9 43774 20647 2 1211.725954 606.8712 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 8.75 3820.8 - 1.00E+06 - - - -1.5193 - 1.802 0.377 - 470.5 1 1 0 -0.0018 11 0 0 0 2.37E+07 2.64E+07 - - - 3.418 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20648.20648.2 0.000679 16-Sep R.GFAFVYFER[166.11].L sp|Q13595|TRA2A_HUMAN 1 1144.5581 0.88 43775 20648 2 1144.558357 573.2863 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3820.8 - 2.16E+06 - - - 0.2237 - 1.613 0.359 - 263.8 1 2 0 0.0003 9 0 0 0 5.78E+07 6.60E+07 - - - 3.0757 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.20649.20649.3 4.70E-05 16/56 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 613.52 43776 20649 3 1658.908728 553.977 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3820.9 - 1.20E+06 - - - -0.2044 - 2.813 0.462 - 268.8 1 2 0 -0.0003 15 0 0 0 1.87E+08 3.04E+05 - - - 6.3895 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20650.20650.2 0.000294 18-Nov K.MPLIGLGTWK[136.11].S "sp|P14550|AK1A1_HUMAN,sp|P15121|ALDR_HUMAN,tr|V9GYG2|V9GYG2_HUMAN,tr|E9PCX2|E9PCX2_HUMAN,tr|Q5T621|Q5T621_HUMAN,tr|V9GYP9|V9GYP9_HUMAN,tr|E9PEF9|E9PEF9_HUMAN" 7 1122.6351 0.75 43777 20650 2 1122.635619 562.3248 Aldo-keto reductase family 1 member A1 OS=Homo sapiens OX=9606 GN=AKR1A1 PE=1 SV=3 8.5 3821 - 617734 - - - 0.4739 - 2.098 0.458 - 393.6 1 2 0 0.0005 10 0 0 0 1.18E+07 1.56E+07 - - - 4.4919 0.9984 230117_WJC_METTL3_WT_vs_EV_F05.20651.20651.2 0.00259 14-Jun K.ETLLAMFK.Y sp|P26639|SYTC_HUMAN 1 951.5099 2.21 43778 20651 2 951.509296 476.7622 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 6.1 3821.1 - 570117 - - - -0.6768 - 1.399 0.369 - 95.8 1 2 0 -0.0006 8 0 0 0 5.45E+06 2.47E+06 - - - 2.7789 0.9844 230117_WJC_METTL3_WT_vs_EV_F05.20652.20652.2 0.188 12-May K.YPVWLWK.R "sp|Q13084|RM28_HUMAN,tr|A2IDC6|A2IDC6_HUMAN,tr|A2IDC7|A2IDC7_HUMAN,tr|Q4TT37|Q4TT37_HUMAN" 4 990.5327 0.78 43779 20652 2 990.532919 496.2736 "39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4" 8.59 3821.3 - 197132 - - - 0.1969 - 1.093 0.177 - 75.7 4 2 0 0.0002 7 0 0 0 7.53E+06 9.71E+06 - - - 0.3611 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20656.20656.2 0.22 16-Sep R.GFAFVYFER.L sp|Q13595|TRA2A_HUMAN 1 1134.5498 0.88 43781 20656 2 1134.549478 568.2822 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3821.8 - 2.29E+06 - - - -0.3111 - 1.79 0.379 - 333.9 1 2 0 -0.0004 9 0 0 0 5.78E+07 6.60E+07 - - - 3.5246 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.20658.20658.2 0.0174 16-Sep K.IGFPWSEIR[166.11].N "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 1113.5847 0.85 43783 20658 2 1113.584903 557.7996 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 6 3822 - 340235 - - - 0.2272 - 1.567 0.273 - 220 1 2 0 0.0003 9 0 0 0 1.31E+07 1.55E+07 - - - 2.3568 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.20660.20660.2 0.283 14-Jul R.VIFGLFGK.T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 879.5218 0.61 43785 20660 2 879.521241 440.7682 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.72 3822.2 - 181731 - - - -0.664 - 1.451 0.31 - 129.3 1 2 0 -0.0006 8 0 0 0 2.82E+07 4.65E+07 - - - 2.4532 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.20661.20661.2 0.0139 12-Jul K.YPVWLWK[136.11].R "sp|Q13084|RM28_HUMAN,tr|A2IDC6|A2IDC6_HUMAN,tr|A2IDC7|A2IDC7_HUMAN,tr|Q4TT37|Q4TT37_HUMAN" 4 998.5469 0.81 43786 20661 2 998.545967 500.2807 "39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4" 8.59 3822.4 - 167301 - - - -0.9584 - 1.378 0.305 - 131.8 1 2 0 -0.001 7 0 0 0 7.53E+06 9.35E+06 - - - 2.3094 1 230117_WJC_METTL3_WT_vs_EV_F05.20665.20665.2 0.000212 16-Oct R.YLTVAAIFR.G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1052.6019 2.94 43788 20665 2 1052.600731 527.3082 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3822.9 - 752983 - - - -1.0783 - 2.088 0.54 - 365.2 1 2 0 -0.0011 9 0 0 0 3.07E+07 1.04E+07 - - - 5.159 0.999 230117_WJC_METTL3_WT_vs_EV_F05.20666.20666.2 0.000558 18-Sep K.MPLIGLGTWK.S "sp|P14550|AK1A1_HUMAN,sp|P15121|ALDR_HUMAN,tr|V9GYG2|V9GYG2_HUMAN,tr|E9PCX2|E9PCX2_HUMAN,tr|Q5T621|Q5T621_HUMAN,tr|V9GYP9|V9GYP9_HUMAN,tr|E9PEF9|E9PEF9_HUMAN" 7 1114.6209 0.75 43789 20666 2 1114.619911 558.3177 Aldo-keto reductase family 1 member A1 OS=Homo sapiens OX=9606 GN=AKR1A1 PE=1 SV=3 8.5 3822.9 - 473215 - - - -0.8756 - 1.865 0.382 - 183.5 1 2 0 -0.001 10 0 0 0 1.18E+07 1.56E+07 - - - 3.6019 1 230117_WJC_METTL3_WT_vs_EV_F05.20667.20667.2 6.17E-08 26-Nov K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.09 43790 20667 2 1416.842453 709.4289 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3823 - 233990 - - - -0.5032 - 2.508 0.599 - 399.7 1 2 0 -0.0007 14 0 0 0 6.85E+07 6.26E+07 - - - 5.7724 1 230117_WJC_METTL3_WT_vs_EV_F05.20671.20671.2 0.0002 13/24 R.GAVGALLVYDIAK[136.11].H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1296.7533 1.6 43794 20671 2 1296.753242 649.3839 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3823.4 - 245107 - - - -0.0355 - 2.683 0.435 - 713.7 1 2 0 0 13 0 0 0 1.41E+07 8.81E+06 - - - 4.7869 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.20675.20675.2 0.161 22-Oct R.LTVLLPLAAAER[166.11].D sp|Q8IZ52|CHSS2_HUMAN 1 1275.779 0.96 43798 20675 2 1275.777889 638.8968 Chondroitin sulfate synthase 2 OS=Homo sapiens OX=9606 GN=CHPF PE=1 SV=2 6 3823.9 - 0 - - - -0.8654 - 1.844 0.197 - 218.9 1 2 0 -0.0011 12 0 0 0 3.00E+06 3.13E+06 - - - 2.1058 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.20676.20676.2 0.0766 22-Dec K.ALLVEVQLLESK[136.11].T sp|O00231|PSD11_HUMAN 1 1348.8057 2.6 43799 20676 2 1348.807204 675.4101 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.53 3824.1 - 0 - - - 1.1017 - 2.239 0.258 - 444.4 1 2 0 0.0015 12 0 0 0 5.40E+06 2.07E+06 - - - 3.0669 1 230117_WJC_METTL3_WT_vs_EV_F05.20686.20686.2 0.00333 16-Oct R.YLTVAAIFR[166.11].G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1062.6101 2.94 43807 20686 2 1062.610079 532.3123 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3825.2 - 2.54E+06 - - - -0.0536 - 2.137 0.455 - 340.3 1 2 0 -0.0001 9 0 0 0 3.07E+07 1.04E+07 - - - 4.5986 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.20688.20688.2 9.53E-06 24-Dec R.GAVGALLVYDIAK.H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1288.7391 1.41 43809 20688 2 1288.73745 645.3768 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3825.5 - 1.23E+06 - - - -1.271 - 2.72 0.361 - 643.8 1 2 0 -0.0016 13 0 0 0 1.09E+07 7.77E+06 - - - 4.275 1 230117_WJC_METTL3_WT_vs_EV_F05.20689.20689.3 1.38E-08 18/52 K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.33 43810 20689 3 1408.829792 470.6169 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3825.6 - 1.14E+06 - - - 0.5863 - 3.45 0.619 - 472 1 2 0 0.0008 14 0 0 0 1.75E+07 1.31E+07 - - - 8.732 1 230117_WJC_METTL3_WT_vs_EV_F05.20691.20691.3 9.21E-06 17/52 K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.33 43812 20691 3 1416.840706 473.2883 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3825.9 - 1.03E+06 - - - -1.7363 - 3.08 0.563 - 404.1 1 2 0 -0.0025 14 0 0 0 1.75E+07 1.31E+07 - - - 7.8057 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.20693.20693.2 0.000789 30-Sep K.LPPPLSAPVAGLAALK.A sp|Q14781|CBX2_HUMAN 1 1513.9232 2.9 43814 20693 2 1513.921876 757.9689 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.75 3826.2 - 650671 - - - -0.8752 - 1.737 0.396 - 177.9 1 2 0 -0.0013 16 0 0 0 2.50E+06 8.62E+05 - - - 3.3229 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.20694.20694.2 0.00844 18-Sep R.QALTDFLLAR[166.11].K "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1156.648 0.77 43815 20694 2 1156.647143 579.3313 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.84 3826.3 - 599394 - - - -0.7219 - 1.679 0.288 - 153.2 1 2 0 -0.0008 10 0 0 0 2.48E+06 3.21E+06 - - - 2.6144 1 230117_WJC_METTL3_WT_vs_EV_F05.20696.20696.2 7.46E-05 13/20 K.ILLTQENPFFR.K sp|Q08J23|NSUN2_HUMAN 1 1376.7452 2.27 43816 20696 2 1376.745312 689.3799 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3826.6 - 3.50E+06 - - - 0.0552 - 2.613 0.44 - 747.6 1 2 0 0.0001 11 0 0 0 8.00E+07 3.53E+07 - - - 4.8892 1 230117_WJC_METTL3_WT_vs_EV_F05.20701.20701.2 2.02E-07 21/34 K.ILDSFAAAPVPTTTLVLK.S sp|P18583|SON_HUMAN 1 1856.0659 1.71 43820 20701 2 1856.059671 929.0402 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3827.2 - 744383 - - - -3.3571 - 3.46 0.594 - 975.8 1 2 0 -0.0062 18 0 0 0 8.61E+06 5.04E+06 - - - 6.478 0.9951 230117_WJC_METTL3_WT_vs_EV_F05.20705.20705.2 0.00328 26-Oct R.LFLVGSSLNGFGTR[166.11].S "sp|Q6PIY7|GLD2_HUMAN,tr|D6RAF2|D6RAF2_HUMAN" 2 1476.7964 1.87 43824 20705 2 1476.790637 739.4055 Poly(A) RNA polymerase GLD2 OS=Homo sapiens OX=9606 GN=TENT2 PE=1 SV=1 9.75 3827.7 - 440861 - - - -3.9254 - 2.262 0.425 - 167.3 1 2 0 -0.0058 14 0 0 0 3.20E+06 1.71E+06 - - - 4.2266 0.9953 230117_WJC_METTL3_WT_vs_EV_F05.20709.20709.2 0.000886 22-Oct K.LFISGLPFSC[160.03]TK.E "sp|Q15020|SART3_HUMAN,tr|H0YHU8|H0YHU8_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 3 1368.7112 999 43828 20709 2 1368.709267 685.3629 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 8.22 3828.2 - 233374 - - - -1.3823 - 1.608 0.241 - 245.1 1 2 0 -0.0019 12 0 0 0 3.61E+06 0.00E+00 - - - 2.0702 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.20711.20711.2 0.00236 26-Nov K.VLFLLGADGGC[160.03]ITR.Q "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1490.7915 2.18 43829 20711 2 1490.79061 746.403 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 5.8 3828.4 - 0 - - - -0.6205 - 2.199 0.436 - 373.4 1 2 0 -0.0009 14 0 0 0 3.29E+06 1.51E+06 - - - 4.2385 1 230117_WJC_METTL3_WT_vs_EV_F05.20714.20714.2 2.63E-06 26-Aug K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.09 43831 20714 2 1408.830288 705.4218 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3828.7 - 1.50E+06 - - - 0.9384 - 2.092 0.588 - 217.4 1 2 0 0.0013 14 0 0 0 6.85E+07 6.26E+07 - - - 5.2358 1 230117_WJC_METTL3_WT_vs_EV_F05.20719.20719.2 9.62E-09 13/26 R.VVAVFVQGPAWQFK.G "sp|Q6P1J9|CDC73_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1574.8609 1.24 43836 20719 2 1574.861406 788.4377 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.72 3829.2 - 196901 - - - 0.2991 - 2.839 0.538 - 503.2 1 2 0 0.0005 14 0 0 0 2.14E+06 1.73E+06 - - - 5.633 1 230117_WJC_METTL3_WT_vs_EV_F05.20725.20725.2 1.80E-09 21/34 K.ILDSFAAAPVPTTTLVLK[136.11].S sp|P18583|SON_HUMAN 1 1864.0801 1.71 43840 20725 2 1864.080774 933.0473 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3830 - 724638 - - - 0.3605 - 3.525 0.588 - 909.1 1 2 0 0.0007 18 0 0 0 8.61E+06 5.04E+06 - - - 6.4812 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.20727.20727.2 0.0197 16-Aug K.IIAATFLFK.W sp|Q13907|IDI1_HUMAN 1 1022.6165 6.76 43842 20727 2 1022.616559 512.3155 Isopentenyl-diphosphate Delta-isomerase 1 OS=Homo sapiens OX=9606 GN=IDI1 PE=1 SV=2 8.75 3830.3 - 382035 - - - 0.1027 - 1.564 0.211 - 125.2 1 2 0 0.0001 9 0 0 0 2.69E+06 3.98E+05 - - - 1.8933 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20730.20730.2 0.00257 20-Sep K.LIGVYTDFAFR[166.11].L sp|Q5SY16|NOL9_HUMAN 1 1310.6898 0.53 43845 20730 2 1310.691059 656.3522 Polynucleotide 5'-hydroxyl-kinase NOL9 OS=Homo sapiens OX=9606 GN=NOL9 PE=1 SV=1 5.84 3830.6 - 275660 - - - 0.9278 - 1.765 0.388 - 255.5 1 2 0 0.0012 11 0 0 0 2.37E+06 4.49E+06 - - - 3.4434 1 230117_WJC_METTL3_WT_vs_EV_F05.20731.20731.3 8.69E-07 19/60 R.TPEQVAEEEYLLQELR[166.11].K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1955.9716 -1 43846 20731 3 1955.970959 652.9978 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3830.8 - 248199 - - - -0.3057 - 2.993 0.584 - 427.2 1 2 0 -0.0006 16 0 0 0 0.00E+00 0.00E+00 - - - 7.8638 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20734.20734.2 0.0826 12-Jul K.LNIWDWK.T sp|O60508|PRP17_HUMAN 1 973.5022 0.78 43849 20734 2 973.503352 487.7584 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.84 3831.2 - 171888 - - - 1.2327 - 1.638 0.295 - 170.5 1 2 0 0.0012 7 0 0 0 1.57E+06 2.00E+06 - - - 2.7831 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20735.20735.2 0.00274 14-Sep K.EALLELLR[166.11].L sp|Q13895|BYST_HUMAN 1 965.5785 1.04 43850 20735 2 965.577794 483.7965 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3831.3 - 166826 - - - -0.7332 - 1.974 0.425 - 318.2 1 2 0 -0.0007 8 0 0 0 2.64E+07 2.55E+07 - - - 4.2309 1 230117_WJC_METTL3_WT_vs_EV_F05.20736.20736.2 5.30E-15 20/30 R.TPEQVAEEEYLLQELR.K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1945.9633 -1 43851 20736 2 1945.961831 973.9889 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3831.4 - 158386 - - - -0.7482 - 4.242 0.65 - 1301.4 1 2 0 -0.0015 16 0 0 0 0.00E+00 0.00E+00 - - - 7.3941 0.9673 230117_WJC_METTL3_WT_vs_EV_F05.20737.20737.2 0.000888 22-Nov R.PASPSLQLLPWR.E sp|Q8WUF5|IASPP_HUMAN 1 1363.7612 1.18 43852 20737 2 1363.763315 682.8879 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 10.18 3831.6 - 132641 - - - 1.5355 - 1.968 0.359 - 144 1 1 0 0.0021 12 0 0 0 6.72E+05 5.68E+05 - - - 3.4733 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.20738.20738.2 0.158 12-Jul K.LWYVLLK.E sp|Q9HD33|RM47_HUMAN 1 933.5688 0.77 43853 20738 2 933.569644 467.7917 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 8.59 3831.7 - 126946 - - - 0.9308 - 1.457 0.258 - 134.2 1 2 0 0.0009 7 0 0 0 1.01E+06 1.31E+06 - - - 2.1389 1 230117_WJC_METTL3_WT_vs_EV_F05.20739.20739.2 5.32E-06 15/32 R.FLVGPYQNTIGAAFVAK.V "sp|Q969Q5|RAB24_HUMAN,tr|D6RFW3|D6RFW3_HUMAN" 2 1794.9669 -1 43854 20739 2 1794.968451 898.4907 Ras-related protein Rab-24 OS=Homo sapiens OX=9606 GN=RAB24 PE=1 SV=1 8.59 3831.8 - 120695 - - - 0.8886 - 3.286 0.583 - 452.2 1 2 0 0.0016 17 0 0 0 0.00E+00 0.00E+00 - - - 6.2714 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20743.20743.2 0.000711 13/20 K.ELGIWEPLAVK.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1253.702 10.33 43856 20743 2 1253.701564 627.8583 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3832.4 - 1.74E+06 - - - -0.327 - 2.258 0.405 - 651.1 1 2 0 -0.0004 11 0 0 0 7.26E+08 7.03E+07 - - - 4.2356 1 230117_WJC_METTL3_WT_vs_EV_F05.20745.20745.2 7.09E-08 16/24 K.MVFINNIALAQIK.N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1473.8378 1.35 43858 20745 2 1473.839378 737.9262 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3832.6 - 701950 - - - 1.1005 - 2.744 0.624 - 759.1 1 2 0 0.0016 13 0 0 0 1.71E+07 1.27E+07 - - - 6.2401 1 230117_WJC_METTL3_WT_vs_EV_F05.20746.20746.2 6.72E-08 20/24 K.MVFINNIALAQIK[136.11].N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1481.852 1.35 43859 20746 2 1481.851586 741.9333 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3832.8 - 684826 - - - -0.2497 - 3.025 0.626 - 1230.9 1 2 0 -0.0004 13 0 0 0 1.71E+07 1.27E+07 - - - 6.5054 1 230117_WJC_METTL3_WT_vs_EV_F05.20747.20747.2 0.00296 13/20 R.QLLEEMLTSYR[166.11].L sp|O75688|PPM1B_HUMAN 1 1391.6994 0.46 43860 20747 2 1391.6978 696.857 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3832.9 - 489821 - - - -1.1655 - 2.494 0.419 - 758.6 1 2 0 -0.0016 11 0 0 0 4.85E+07 1.05E+08 - - - 4.6075 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20748.20748.2 0.00858 14-Oct K.EALLELLR.L sp|Q13895|BYST_HUMAN 1 955.5702 1.04 43861 20748 2 955.571033 478.7924 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3833 - 422667 - - - 0.8382 - 2.029 0.398 - 372.3 1 2 0 0.0008 8 0 0 0 2.64E+07 2.55E+07 - - - 4.1143 0.9584 230117_WJC_METTL3_WT_vs_EV_F05.20751.20751.2 0.000526 20-Sep D.GMVPFVFVGTK[136.11].E "sp|P51114|FXR1_HUMAN,sp|Q06787|FMR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 9 1188.6457 0.65 43864 20751 2 1188.647622 595.3301 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 8.75 3833.4 - 357034 - - - 1.6573 - 1.707 0.358 - 241.6 1 1 0 0.002 11 0 0 0 3.63E+06 5.56E+06 - - - 3.1312 1 230117_WJC_METTL3_WT_vs_EV_F05.20755.20755.2 8.02E-05 13/20 R.QLLEEMLTSYR.L sp|O75688|PPM1B_HUMAN 1 1381.6912 0.46 43868 20755 2 1381.691966 691.8529 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3833.9 - 225120 - - - 0.5891 - 2.585 0.529 - 798.1 1 2 0 0.0008 11 0 0 0 4.85E+07 1.05E+08 - - - 5.5172 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20757.20757.2 0.000158 13/22 R.LALFNPDVC[160.03]WDR.N sp|O00483|NDUA4_HUMAN 1 1504.7133 1.76 43870 20757 2 1504.713287 753.3639 Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1 4.21 3834.2 - 200787 - - - 0.002 - 2.68 0.385 - 685.2 1 2 0 0 12 0 0 0 8.18E+06 4.65E+06 - - - 4.4785 1 230117_WJC_METTL3_WT_vs_EV_F05.20762.20762.2 1.24E-06 14/24 K.VLGTAFDPFLGGK.N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1320.7078 8.98 43873 20762 2 1320.704521 661.3612 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3834.9 - 1.16E+08 - - - -2.4737 - 2.443 0.574 - 521.3 1 2 0 -0.0033 13 0 0 0 2.78E+08 3.10E+07 - - - 5.572 0.9923 230117_WJC_METTL3_WT_vs_EV_F05.20763.20763.2 0.00414 20-Nov K.ELGIWEPLAVK[136.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1261.7162 10.33 43874 20763 2 1261.711568 631.8654 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3834.9 - 2.38E+07 - - - -3.6506 - 1.881 0.323 - 410.7 1 2 0 -0.0046 11 0 0 0 7.26E+08 7.03E+07 - - - 3.1344 1 230117_WJC_METTL3_WT_vs_EV_F05.20764.20764.2 8.51E-09 15/24 K.VLGTAFDPFLGGK[136.11].N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1328.722 8.98 43875 20764 2 1328.716812 665.3683 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3835 - 1.34E+07 - - - -3.8955 - 2.734 0.659 - 590.6 1 2 0 -0.0052 13 0 0 0 2.78E+08 3.10E+07 - - - 6.4881 1 230117_WJC_METTL3_WT_vs_EV_F05.20767.20767.2 3.77E-06 15/24 K.LLEQALVIEEQLR.R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1552.8825 1.64 43878 20767 2 1552.877971 777.4485 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3835.2 - 6.89E+06 - - - -2.8895 - 2.925 0.544 - 906.9 1 2 0 -0.0045 13 0 0 0 1.64E+07 9.98E+06 - - - 5.8122 0.9946 230117_WJC_METTL3_WT_vs_EV_F05.20768.20768.2 0.000607 20-Dec K.TLPLFYGSIVR[166.11].F "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1274.7262 1.31 43879 20768 2 1274.721136 638.3704 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 8.41 3835.3 - 5.49E+06 - - - -3.9954 - 1.963 0.436 - 534.8 1 2 0 -0.0051 11 0 0 0 1.91E+07 1.46E+07 - - - 4.0843 1 230117_WJC_METTL3_WT_vs_EV_F05.20770.20770.2 0.000128 17/24 K.LLEQALVIEEQLR[166.11].R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1562.8907 1.64 43881 20770 2 1562.886479 782.4526 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3835.5 - 4.21E+06 - - - -2.7187 - 2.838 0.414 - 1371.7 1 2 0 -0.0043 13 0 0 0 1.63E+07 9.98E+06 - - - 4.7746 1 230117_WJC_METTL3_WT_vs_EV_F05.20771.20771.2 1.75E-06 17/26 K.LGLVGVNLTLDGVK.S "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 1396.829 1.32 43882 20771 2 1396.823895 699.4218 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 3835.7 - 4.16E+06 - - - -3.6304 - 3.187 0.506 - 1092.8 1 2 0 -0.0051 14 0 0 0 1.93E+07 1.46E+07 - - - 5.6854 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20772.20772.3 0.00198 Dec-48 K.LLEQALVIEEQLR.R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1552.8825 1.27 43883 20772 3 1552.878242 518.6348 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3835.8 - 3.59E+06 - - - -2.715 - 2.512 0.444 - 241.2 1 2 0 -0.0042 13 0 0 0 6.12E+06 4.84E+06 - - - 5.9863 1 230117_WJC_METTL3_WT_vs_EV_F05.20773.20773.2 1.61E-08 18/28 K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 0.9 43884 20773 2 1521.868356 761.945 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3835.9 - 3.58E+06 - - - -4.6364 - 3.201 0.635 - 964 1 2 0 -0.0071 15 0 0 0 9.59E+06 1.07E+07 - - - 6.5893 0.9966 230117_WJC_METTL3_WT_vs_EV_F05.20774.20774.2 0.00239 13/24 K.ALVLANPEVSLWR.K "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 1466.8245 1.27 43885 20774 2 1466.81972 734.4196 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6.05 3836 - 3.35E+06 - - - -3.2921 - 2.437 0.38 - 566 1 2 0 -0.0048 13 0 0 0 8.68E+06 6.81E+06 - - - 4.1323 1 230117_WJC_METTL3_WT_vs_EV_F05.20775.20775.2 2.26E-06 16/30 R.IASLPVEVQEVSLLDK.L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1738.9717 2.83 43886 20775 2 1738.964166 870.4931 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.14 3836.2 - 3.28E+06 - - - -4.3135 - 2.938 0.535 - 674.6 1 2 0 -0.0075 16 0 0 0 2.42E+07 8.55E+06 - - - 5.6398 1 230117_WJC_METTL3_WT_vs_EV_F05.20776.20776.2 9.16E-07 18/28 K.TVAGQDAVIVLLGTR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1511.8671 0.9 43887 20776 2 1511.859926 756.9408 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3836.3 - 2.96E+06 - - - -4.7729 - 3.208 0.604 - 916.6 1 2 0 -0.0072 15 0 0 0 9.59E+06 1.07E+07 - - - 6.3657 0.9831 230117_WJC_METTL3_WT_vs_EV_F05.20777.20777.3 0.0657 Oct-48 K.LLEQALVIEEQLR[166.11].R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1562.8907 1.27 43888 20777 3 1562.886311 521.9709 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3836.4 - 2.87E+06 - - - -2.8262 - 1.931 0.203 - 167.6 1 2 0 -0.0044 13 0 0 0 6.12E+06 4.84E+06 - - - 2.5862 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.20778.20778.2 2.94E-05 20-Dec K.SLPASLSFLVK.L "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN" 5 1160.6805 1.62 43889 20778 2 1160.679532 581.3475 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 8.47 3836.6 - 2.41E+06 - - - -0.8435 - 1.959 0.392 - 279 1 2 0 -0.001 11 0 0 0 6.45E+06 3.98E+06 - - - 3.7551 0.9956 230117_WJC_METTL3_WT_vs_EV_F05.20779.20779.2 0.000422 20-Dec K.LLPAITILGC[160.03]R.V "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 2 1225.7217 2.68 43890 20779 2 1225.716844 613.8681 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 8.25 3836.7 - 2.40E+06 - - - -3.9324 - 2.203 0.455 - 563.6 1 2 0 -0.0048 11 0 0 0 1.55E+07 5.78E+06 - - - 4.5368 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20780.20780.3 6.30E-07 17/56 K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 0.96 43891 20780 3 1521.870865 508.2991 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3836.8 - 2.30E+06 - - - -2.9878 - 2.9 0.5 - 442.1 1 2 0 -0.0045 15 0 0 0 5.12E+06 5.36E+06 - - - 6.8915 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20781.20781.3 4.56E-06 17/56 K.TVAGQDAVIVLLGTR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1511.8671 0.9 43892 20781 3 1511.862252 504.963 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3836.9 - 2.01E+06 - - - -3.2344 - 2.712 0.524 - 502.7 1 2 0 -0.0049 15 0 0 0 5.12E+06 5.72E+06 - - - 6.9841 1 230117_WJC_METTL3_WT_vs_EV_F05.20787.20787.2 4.21E-06 14/26 K.LGLVGVNLTLDGVK[136.11].S "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 1404.8432 1.32 43897 20787 2 1404.842898 703.4289 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 3837.4 - 1.78E+06 - - - -0.1908 - 3.106 0.527 - 637.8 1 2 0 -0.0003 14 0 0 0 1.93E+07 1.46E+07 - - - 5.7774 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.20788.20788.2 0.00114 22-Dec K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 1.2 43898 20788 2 1314.789572 658.4028 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3837.5 - 973053 - - - -1.1804 - 2.183 0.448 - 491.3 1 2 0 -0.0016 12 0 0 0 1.28E+08 1.07E+08 - - - 4.4036 0.8846 230117_WJC_METTL3_WT_vs_EV_F05.20790.20790.2 0.00411 16-Jul R.FYTLIPHDF.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1151.5651 - 43900 20790 2 1151.567857 576.7898 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.08 3837.7 - 401825 - - - 2.3533 - 1.177 0.355 - 134.8 1 1 0 0.0027 9 0 0 0 - - - - - 2.1337 0.9797 230117_WJC_METTL3_WT_vs_EV_F05.20796.20796.3 0.0197 Sep-44 R.EGFLDTLVVLHR.A "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 1397.7667 2.78 43906 20796 3 1397.760742 466.9295 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.32 3838.5 - 254036 - - - -4.2625 - 1.855 0.259 - 68.5 1 2 0 -0.006 12 0 0 0 2.22E+06 7.98E+05 - - - 3.1386 1 230117_WJC_METTL3_WT_vs_EV_F05.20800.20800.2 7.91E-06 28-Aug R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 -1 43910 20800 2 2001.959689 1001.9941 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3839 - 0 - - - -7.0151 - 1.9 0.562 - 54.9 1 2 0 -0.014 15 0 0 0 0.00E+00 0.00E+00 - - - 4.7655 1 230117_WJC_METTL3_WT_vs_EV_F05.20806.20806.2 1.02E-06 26-Sep R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.86 43913 20806 2 1669.891386 835.9552 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3839.7 - 3.42E+06 - - - -2.7211 - 2.011 0.612 - 250.3 1 2 0 -0.0045 14 0 0 0 7.73E+07 9.00E+07 - - - 5.313 1 230117_WJC_METTL3_WT_vs_EV_F05.20807.20807.2 2.41E-06 24-Dec R.LGSTIFVANLDFK.V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1423.7711 1.9 43914 20807 2 1423.771996 712.8928 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3839.7 - 3.40E+06 - - - 0.6174 - 2.707 0.58 - 641.6 1 2 0 0.0009 13 0 0 0 2.67E+07 1.40E+07 - - - 5.8805 1 230117_WJC_METTL3_WT_vs_EV_F05.20808.20808.2 1.94E-09 26-Dec R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.86 43915 20808 2 1661.88162 831.9481 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3839.8 - 2.39E+06 - - - -0.0662 - 2.466 0.654 - 427.9 1 2 0 -0.0001 14 0 0 0 7.71E+07 9.00E+07 - - - 6.1364 1 230117_WJC_METTL3_WT_vs_EV_F05.20811.20811.2 4.00E-09 24-Dec R.LGSTIFVANLDFK[136.11].V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1431.7853 1.9 43918 20811 2 1431.787121 716.8999 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3839.9 - 1.60E+06 - - - 1.26 - 2.62 0.558 - 636.7 1 2 0 0.0018 13 0 0 0 2.67E+07 1.40E+07 - - - 5.6338 1 230117_WJC_METTL3_WT_vs_EV_F05.20812.20812.2 8.69E-06 13/30 R.IASLPVEVQEVSLLDK[136.11].L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1746.9859 2.83 43919 20812 2 1746.987746 874.5002 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.14 3840 - 1.31E+06 - - - 1.0756 - 2.54 0.509 - 403.3 1 2 0 0.0019 16 0 0 0 2.42E+07 8.55E+06 - - - 5.0917 0.9922 230117_WJC_METTL3_WT_vs_EV_F05.20815.20815.3 0.00136 Sep-40 K.VPPPWLIAMQR.Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1306.722 1.26 43922 20815 3 1306.720559 436.5813 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3840.3 - 180154 - - - -1.1012 - 1.665 0.213 - 132.9 1 2 0 -0.0014 11 0 0 0 1.72E+06 1.37E+06 - - - 2.3627 0.993 230117_WJC_METTL3_WT_vs_EV_F05.20816.20816.2 0.601 12-May K.FFDLFEK.C "sp|O43314|VIP2_HUMAN,sp|O94830|DDHD2_HUMAN,tr|A0A087WZV0|A0A087WZV0_HUMAN,tr|D6RBU4|D6RBU4_HUMAN" 4 944.4644 0.87 43923 20816 2 944.466019 473.2395 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 OS=Homo sapiens OX=9606 GN=PPIP5K2 PE=1 SV=3 4.37 3840.4 - 0 - - - 1.746 - 1.041 0.214 - 57.2 1 2 0 0.0016 7 0 0 0 7.14E+05 8.17E+05 - - - 0.7484 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.20818.20818.3 0.000599 Nov-44 K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 1.64 43925 20818 3 1314.79217 439.271 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3840.7 - 165824 - - - 0.7956 - 2.015 0.393 - 175.4 1 2 0 0.001 12 0 0 0 1.74E+06 1.06E+06 - - - 4.8633 1 230117_WJC_METTL3_WT_vs_EV_F05.20823.20823.2 3.69E-05 13/22 K.LVTLPVSFAQLK[136.11].N sp|Q96AG4|LRC59_HUMAN 1 1322.8053 1.2 43927 20823 2 1322.803687 662.4099 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3841.3 - 6.06E+06 - - - -1.2375 - 2.306 0.505 - 520.6 1 2 0 -0.0016 12 0 0 0 1.28E+08 1.07E+08 - - - 4.9688 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20825.20825.2 0.00166 16-Sep R.YSFIQALVR.R sp|Q92621|NU205_HUMAN 1 1095.6077 1.41 43929 20825 2 1095.607197 548.8111 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 8.75 3841.5 - 948062 - - - -0.4409 - 1.77 0.424 - 295 1 2 0 -0.0005 9 0 0 0 9.37E+06 6.66E+06 - - - 3.8244 1 230117_WJC_METTL3_WT_vs_EV_F05.20837.20837.3 1.19E-08 20/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 43940 20837 3 1603.763602 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3843 - 9.89E+06 - - - -0.2108 - 3.094 0.617 - 575 1 2 0 -0.0003 12 0 0 0 1.04E+08 0.00E+00 - - - 8.5496 0.9899 230117_WJC_METTL3_WT_vs_EV_F05.20839.20839.3 0.296 Sep-52 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.92 43941 20839 3 1669.8946 557.6393 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3843.2 - 706110 - - - -0.7965 - 1.45 0.225 - 91.7 1 2 0 -0.0013 14 0 0 0 9.53E+06 1.04E+07 - - - 2.0356 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20840.20840.3 0.000833 Nov-52 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.92 43942 20840 3 1661.880444 554.9679 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3843.3 - 503267 - - - -0.7738 - 1.743 0.418 - 120.4 1 2 0 -0.0013 14 0 0 0 9.53E+06 1.04E+07 - - - 4.6765 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.20842.20842.2 0.00275 20-Nov K.VSVFFGGLSIK.K "sp|O00148|DX39A_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|A0A0D9SEM9|A0A0D9SEM9_HUMAN" 3 1152.6543 2.58 43944 20842 2 1152.660505 577.3344 ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2 8.72 3843.4 - 405651 - - - 5.3867 - 2.033 0.467 - 408.5 1 2 0 0.0062 11 0 0 0 9.87E+06 3.83E+06 - - - 4.4077 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.20853.20853.2 0.0155 16-Aug K.ITFLLQAIR.N "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1073.6597 1.29 43953 20853 2 1073.659512 537.8371 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 3844.7 - 432598 - - - -0.19 - 1.861 0.411 - 193.4 1 2 0 -0.0002 9 0 0 0 1.14E+07 8.78E+06 - - - 3.8735 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20854.20854.2 0.00188 16-Oct K.ITFLLQAIR[166.11].N "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1083.668 1.29 43954 20854 2 1083.66837 542.8413 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 3844.7 - 502818 - - - 0.3544 - 1.776 0.392 - 313.3 1 2 0 0.0004 9 0 0 0 1.14E+07 8.78E+06 - - - 3.5979 1 230117_WJC_METTL3_WT_vs_EV_F05.20859.20859.2 3.10E-06 24-Nov R.VLLFTDDVALVSK.A "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1418.8021 1.18 43959 20859 2 1418.799744 710.4083 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.21 3845.3 - 72438.8 - - - -1.6479 - 2.503 0.573 - 276.8 1 2 0 -0.0023 13 0 0 0 3.80E+06 3.22E+06 - - - 5.6272 0.999 230117_WJC_METTL3_WT_vs_EV_F05.20863.20863.2 2.28E-06 20-Sep R.WPDPEDLLTPR.W sp|Q8TAE8|G45IP_HUMAN 1 1337.6616 1.53 43963 20863 2 1337.659528 669.8381 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.03 3845.8 - 0 - - - -1.5236 - 2.076 0.46 - 284.7 1 2 0 -0.002 11 0 0 0 3.77E+06 2.47E+06 - - - 4.4139 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.20868.20868.2 0.0361 24-Aug K.IAVPLIQGYTVLR.L sp|Q8IW92|GLBL2_HUMAN 1 1441.8657 0.98 43968 20868 2 1441.869688 721.9401 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3846.4 - 0 - - - 2.7756 - 1.651 0.212 - 170.2 1 2 0 0.004 13 0 0 0 3.60E+06 3.67E+06 - - - 1.8924 0.996 230117_WJC_METTL3_WT_vs_EV_F05.20869.20869.2 0.0281 14-Aug R.DFLLDIAR.Q "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 961.5233 1.29 43969 20869 2 961.521207 481.7689 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 3846.6 - 0 - - - -2.158 - 1.561 0.326 - 305 1 2 0 -0.0021 8 0 0 0 1.94E+07 1.50E+07 - - - 2.7913 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20873.20873.2 0.00133 20-Sep K.VAVFFGGLSIK[136.11].K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1144.6736 0.89 43972 20873 2 1144.675014 573.3441 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3847.1 - 564180 - - - 1.2519 - 2.192 0.382 - 242.2 1 2 0 0.0014 11 0 0 0 1.20E+07 1.35E+07 - - - 3.9851 1 230117_WJC_METTL3_WT_vs_EV_F05.20879.20879.2 0.015 18-Nov R.MALLATVLGR.F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1043.6161 2.58 43978 20879 2 1043.616711 522.8153 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.5 3847.5 - 502386 - - - 0.551 - 2.333 0.462 - 628.7 1 2 0 0.0006 10 0 0 0 1.45E+07 5.63E+06 - - - 4.8178 1 230117_WJC_METTL3_WT_vs_EV_F05.20880.20880.2 3.68E-05 20-Dec K.VAVFFGGLSIK.K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1136.6594 0.89 43979 20880 2 1136.659153 569.337 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3847.6 - 475601 - - - -0.2006 - 2.391 0.502 - 540.5 1 2 0 -0.0002 11 0 0 0 1.20E+07 1.34E+07 - - - 5.1069 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.20881.20881.2 0.0347 14-Jul R.DFLLDIAR[166.11].Q "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 971.5316 1.29 43980 20881 2 971.532919 486.7731 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 3847.7 - 382407 - - - 1.4071 - 1.391 0.284 - 195.8 1 2 0 0.0014 8 0 0 0 1.94E+07 1.50E+07 - - - 2.1335 0.9871 230117_WJC_METTL3_WT_vs_EV_F05.20883.20883.2 0.00618 12-Jun K.YFLWVVK.F sp|P62993|GRB2_HUMAN 1 953.5375 17.07 43982 20883 2 953.53749 477.776 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 8.59 3847.9 - 308986 - - - 0.0157 - 1.211 0.123 - 120.2 1 2 0 0 7 0 0 0 6.29E+06 3.69E+05 - - - 0.5561 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.20886.20886.2 0.299 18-Oct R.SDLVLLYELK[136.11].Q sp|Q9NPF5|DMAP1_HUMAN 1 1199.6893 1.22 43984 20886 2 1199.69044 600.8519 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.37 3848.3 - 1.75E+06 - - - 0.9577 - 2.032 0.277 - 316.9 1 2 0 0.0011 10 0 0 0 1.52E+07 1.24E+07 - - - 3.0657 1 230117_WJC_METTL3_WT_vs_EV_F05.20894.20894.2 0.000443 18-Oct R.DFILPISDVR.A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|Q4VXM0|Q4VXM0_HUMAN,tr|Q4VXM1|Q4VXM1_HUMAN" 5 1173.6394 2.4 43991 20894 2 1173.636949 587.827 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.21 3848.9 - 2.27E+06 - - - -2.0662 - 2.21 0.488 - 469.1 1 2 0 -0.0024 10 0 0 0 1.54E+07 6.40E+06 - - - 4.8581 1 230117_WJC_METTL3_WT_vs_EV_F05.20895.20895.2 0.00015 20-Dec R.TSLGNVVLLLK.S "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1155.7227 1.73 43992 20895 2 1155.721755 578.8686 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 8.41 3849 - 2.19E+06 - - - -0.8263 - 2.509 0.421 - 425.3 1 2 0 -0.001 11 0 0 0 8.96E+06 5.19E+06 - - - 4.6387 1 230117_WJC_METTL3_WT_vs_EV_F05.20896.20896.2 2.11E-05 13/20 R.FDEISFVNFAR[166.11].G sp|Q08945|SSRP1_HUMAN 1 1353.6593 0.47 43993 20896 2 1353.657602 677.8369 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3849.1 - 2.01E+06 - - - -1.233 - 2.388 0.477 - 719.3 1 2 0 -0.0017 11 0 0 0 4.29E+06 9.04E+06 - - - 4.9184 0.9919 230117_WJC_METTL3_WT_vs_EV_F05.20897.20897.2 0.000166 20-Dec R.FDEISFVNFAR.G sp|Q08945|SSRP1_HUMAN 1 1343.651 -1 43994 20897 2 1343.659824 672.8328 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3849.2 - 1.69E+06 - - - 6.5664 - 1.932 0.368 - 369.2 1 2 0 0.0088 11 0 0 0 0.00E+00 0.00E+00 - - - 3.5378 1 230117_WJC_METTL3_WT_vs_EV_F05.20898.20898.2 0.000122 13/24 K.AAILPTSIFLTNK[136.11].K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1395.8217 0.45 43995 20898 2 1395.820898 698.9181 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3849.3 - 1.55E+06 - - - -0.576 - 2.584 0.473 - 486.1 1 2 0 -0.0008 13 0 0 0 1.86E+07 4.15E+07 - - - 4.9708 1 230117_WJC_METTL3_WT_vs_EV_F05.20899.20899.2 1.62E-07 22-Oct K.ITAEEMYDIFGK.Y sp|Q9Y3B4|SF3B6_HUMAN 1 1415.6643 2.6 43996 20899 2 1415.662676 708.8394 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.14 3849.4 - 1.19E+06 - - - -1.1246 - 2.303 0.61 - 357.3 1 2 0 -0.0016 12 0 0 0 4.54E+06 1.75E+06 - - - 5.7409 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20904.20904.2 0.00088 24-Dec R.VLLFTDDVALVSK[136.11].A "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1426.8163 1.18 44001 20904 2 1426.817668 714.4154 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.21 3850 - 934356 - - - 0.9714 - 2.127 0.486 - 353.4 1 2 0 0.0014 13 0 0 0 3.80E+06 3.22E+06 - - - 4.5672 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.20910.20910.2 0.000332 24-Dec K.IAVPLIQGYTVLR[166.11].L sp|Q8IW92|GLBL2_HUMAN 1 1451.874 0.98 44006 20910 2 1451.880905 726.9443 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3850.8 - 403930 - - - 4.7862 - 2.344 0.418 - 505.8 1 2 0 0.0069 13 0 0 0 3.60E+06 3.67E+06 - - - 4.3125 1 230117_WJC_METTL3_WT_vs_EV_F05.20911.20911.2 2.20E-05 24-Dec K.AAILPTSIFLTNK.K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1387.8075 0.45 44007 20911 2 1387.807084 694.911 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3850.9 - 1.25E+06 - - - -0.3012 - 2.399 0.469 - 379.1 1 2 0 -0.0004 13 0 0 0 1.86E+07 4.16E+07 - - - 4.7507 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.20912.20912.2 0.261 16-Sep R.DLLFQALGR.T sp|Q9NSD9|SYFB_HUMAN 1 1031.5764 4.36 44008 20912 2 1031.578918 516.7955 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 5.84 3851 - 1.16E+06 - - - 2.4603 - 1.649 0.226 - 279.2 1 2 0 0.0025 9 0 0 0 1.34E+07 3.08E+06 - - - 2.1565 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20915.20915.2 0.00129 18-Aug R.DFILPISDVR[166.11].A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|Q4VXM0|Q4VXM0_HUMAN,tr|Q4VXM1|Q4VXM1_HUMAN" 5 1183.6476 2.4 44011 20915 2 1183.64719 592.8311 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.21 3851.3 - 794185 - - - -0.3836 - 1.901 0.378 - 217.9 1 2 0 -0.0005 10 0 0 0 1.54E+07 6.40E+06 - - - 3.6258 1 230117_WJC_METTL3_WT_vs_EV_F05.20916.20916.2 2.01E-06 26-Dec K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 46.75 44012 20916 2 1613.801263 807.9078 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3851.3 - 777987 - - - 0.1035 - 2.074 0.516 - 271.6 1 2 0 0.0002 14 0 0 0 1.44E+07 3.09E+05 - - - 4.6827 1 230117_WJC_METTL3_WT_vs_EV_F05.20919.20919.2 0.000136 20-Dec R.PLEVFMC[160.03]SVLK.R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1321.6774 -1 44015 20919 2 1321.677416 661.846 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.38 3851.7 - 400507 - - - 0 - 2.524 0.585 - 466.4 1 1 0 0 11 0 0 0 0.00E+00 0.00E+00 - - - 5.8664 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20920.20920.2 0.000247 24-Oct K.LIHIPINNIIVGG.- sp|P60059|SC61G_HUMAN 1 1371.8238 - 44016 20920 2 1371.824409 686.9192 Protein transport protein Sec61 subunit gamma OS=Homo sapiens OX=9606 GN=SEC61G PE=1 SV=1 6.74 3851.9 - 359717 - - - 0.4286 - 2.032 0.452 - 191.9 1 2 0 0.0006 13 0 0 0 - - - - - 4.199 1 230117_WJC_METTL3_WT_vs_EV_F05.20925.20925.2 4.58E-06 13/20 R.PLEVFMC[160.03]SVLK[136.11].R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1329.6916 3.16 44021 20925 2 1329.689233 665.8531 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.38 3852.5 - 234941 - - - -1.7921 - 2.636 0.587 - 529.5 1 1 0 -0.0024 11 0 0 0 1.18E+07 3.72E+06 - - - 5.9979 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.20930.20930.3 2.40E-07 13/52 K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 -1 44024 20930 3 1613.801437 538.941 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3853 - 1.45E+06 - - - 0.2113 - 2.314 0.445 - 264.4 1 2 0 0.0003 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7308 0.999 230117_WJC_METTL3_WT_vs_EV_F05.20932.20932.2 0.0296 14-Jul R.TLFGFLGK.L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 881.5011 0.63 44026 20932 2 881.501904 441.7578 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3853.2 - 6.10E+06 - - - 0.9234 - 1.232 0.378 - 145.9 1 2 0 0.0008 8 0 0 0 1.79E+07 2.84E+07 - - - 2.4619 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20933.20933.2 0.00349 14-Jul R.TLFGFLGK[136.11].L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 889.5153 1.53 44027 20933 2 889.515779 445.7649 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3853.3 - 4.35E+06 - - - 0.5497 - 1.48 0.42 - 146.4 1 2 0 0.0005 8 0 0 0 1.56E+07 1.02E+07 - - - 3.3253 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.20934.20934.2 0.00135 14-Sep R.VFLWGSFR[166.11].D "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1020.5421 1.22 44028 20934 2 1020.542918 511.2783 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 9.72 3853.4 - 2.23E+06 - - - 0.8437 - 1.659 0.319 - 418.2 1 2 0 0.0009 8 0 0 0 6.85E+06 5.60E+06 - - - 2.9236 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20935.20935.2 9.98E-06 16-Sep R.DIVQFVPFR.E "sp|Q96FN4|CPNE2_HUMAN,sp|O75131|CPNE3_HUMAN,sp|O95741|CPNE6_HUMAN,sp|Q86YQ8|CPNE8_HUMAN,sp|Q8IYJ1|CPNE9_HUMAN,sp|Q9UBL6|CPNE7_HUMAN,sp|Q9HCH3|CPNE5_HUMAN,sp|Q96A23|CPNE4_HUMAN,tr|E7ENV7|E7ENV7_HUMAN" 9 1119.6077 3.41 44029 20935 2 1119.60914 560.8111 Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3 5.84 3853.5 - 1.83E+06 - - - 1.304 - 1.977 0.434 - 361.8 1 2 0 0.0015 9 0 0 0 8.14E+06 2.39E+06 - - - 4.2179 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20937.20937.2 0.000302 20-Nov K.LLVSGFWGVAR.H "sp|Q9UBM7|DHCR7_HUMAN,tr|A0A804HI25|A0A804HI25_HUMAN,tr|A0A804HJQ7|A0A804HJQ7_HUMAN,tr|H0YE57|H0YE57_HUMAN" 4 1203.6764 2.17 44031 20937 2 1203.679637 602.8455 7-dehydrocholesterol reductase OS=Homo sapiens OX=9606 GN=DHCR7 PE=1 SV=1 9.75 3853.7 - 1.60E+06 - - - 2.666 - 1.99 0.429 - 355.4 1 2 0 0.0032 11 0 0 0 4.54E+06 2.09E+06 - - - 4.0702 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.20940.20940.2 0.00147 20-Sep K.LLVSGFWGVAR[166.11].H "sp|Q9UBM7|DHCR7_HUMAN,tr|A0A804HI25|A0A804HI25_HUMAN,tr|A0A804HJQ7|A0A804HJQ7_HUMAN,tr|H0YE57|H0YE57_HUMAN" 4 1213.6847 2.45 44034 20940 2 1213.689022 607.8496 7-dehydrocholesterol reductase OS=Homo sapiens OX=9606 GN=DHCR7 PE=1 SV=1 9.75 3854.1 - 1.10E+06 - - - 3.5627 - 1.841 0.357 - 229.2 1 2 0 0.0043 11 0 0 0 5.12E+06 2.09E+06 - - - 3.3275 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20943.20943.2 0.00328 16-Oct R.DIVQFVPFR[166.11].E "sp|Q96FN4|CPNE2_HUMAN,sp|O75131|CPNE3_HUMAN,sp|O95741|CPNE6_HUMAN,sp|Q86YQ8|CPNE8_HUMAN,sp|Q8IYJ1|CPNE9_HUMAN,sp|Q9UBL6|CPNE7_HUMAN,sp|Q9HCH3|CPNE5_HUMAN,sp|Q96A23|CPNE4_HUMAN,tr|E7ENV7|E7ENV7_HUMAN" 9 1129.616 3.41 44037 20943 2 1129.617025 565.8153 Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3 5.84 3854.5 - 874638 - - - 0.9517 - 2.07 0.368 - 452.9 1 2 0 0.0011 9 0 0 0 8.14E+06 2.39E+06 - - - 3.8635 1 230117_WJC_METTL3_WT_vs_EV_F05.20944.20944.2 4.10E-06 16-Sep K.YPENFFLLR.G "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|C9J9S3|C9J9S3_HUMAN,tr|E7ETD8|E7ETD8_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 12 1197.6182 0.58 44038 20944 2 1197.616517 599.8164 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 6 3854.7 - 842693 - - - -1.4429 - 1.871 0.509 - 408.6 1 2 0 -0.0017 9 0 0 0 2.01E+06 3.45E+06 - - - 4.6124 1 230117_WJC_METTL3_WT_vs_EV_F05.20945.20945.2 2.53E-07 13/26 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 -1 44039 20945 2 1535.791943 768.9025 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3854.8 - 793484 - - - 0.9187 - 2.47 0.531 - 489.9 1 2 0 0.0014 14 0 0 0 0.00E+00 0.00E+00 - - - 5.2316 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.20947.20947.2 0.227 14-Aug K.VALLDVFR[166.11].E "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 941.5574 3.03 44041 20947 2 941.558418 471.786 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.81 3855 - 645554 - - - 1.1109 - 1.837 0.228 - 312.7 1 2 0 0.001 8 0 0 0 8.16E+07 2.69E+07 - - - 2.5588 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.20951.20951.3 0.042 Aug-36 K.YRPLFDYFLK.C "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 1360.718 1.02 44044 20951 3 1360.720025 454.5799 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.5 3855.6 - 0 - - - 1.5183 - 1.452 0.255 - 75 1 2 0 0.0021 10 0 0 0 1.98E+06 1.95E+06 - - - 2.4716 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20952.20952.2 0.004 20-Oct R.ILEFIAVSQLR.G "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN,tr|K7ER27|K7ER27_HUMAN" 4 1287.7551 -1 44045 20952 2 1287.757693 644.8848 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 6 3855.7 - 0 - - - 2.0345 - 2.106 0.41 - 364.7 1 2 0 0.0026 11 0 0 0 0.00E+00 0.00E+00 - - - 4.0833 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20953.20953.2 0.035 14-Sep K.VALLDVFR.E "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 931.5491 3.03 44046 20953 2 931.55045 466.7818 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.81 3855.7 - 1.10E+06 - - - 1.4471 - 1.973 0.324 - 446.4 1 2 0 0.0013 8 0 0 0 8.16E+07 2.69E+07 - - - 3.4831 0.9803 230117_WJC_METTL3_WT_vs_EV_F05.20959.20959.2 5.39 20-Jul K.VPPPWLIAMQR[166.11].Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1316.7303 1.68 44052 20959 2 1316.731852 659.3724 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3856.4 - 91731.8 - - - 1.203 - 1.243 0.052 - 130.7 1 2 0 0.0016 11 0 0 0 2.66E+07 1.58E+07 - - - 0.013 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.20966.20966.2 6.76E-06 14/20 R.DSLIFLVDASK[136.11].A sp|P12956|XRCC6_HUMAN 1 1214.6638 0.94 44057 20966 2 1214.665032 608.3392 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.21 3857.3 - 187375 - - - 1.011 - 2.515 0.337 - 562.2 1 2 0 0.0012 11 0 0 0 4.88E+07 5.16E+07 - - - 4.0247 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.20967.20967.2 0.0498 14-Jul R.IPFTFWAR.Y sp|Q9Y5V3|MAGD1_HUMAN 1 1036.5494 1.68 44058 20967 2 1036.551044 519.282 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 9.75 3857.4 - 640378 - - - 1.5503 - 1.458 0.368 - 186.6 1 2 0 0.0016 8 0 0 0 1.14E+07 6.79E+06 - - - 2.8958 1 230117_WJC_METTL3_WT_vs_EV_F05.20969.20969.2 1.30E-06 18-Dec R.WYEWLDPSIK.K sp|Q99459|CDC5L_HUMAN 1 1335.6499 1.9 44060 20969 2 1335.650986 668.8322 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3857.7 - 258696 - - - 0.7839 - 2.042 0.543 - 514.8 1 2 0 0.001 10 0 0 0 2.15E+07 1.14E+07 - - - 5.0441 1 230117_WJC_METTL3_WT_vs_EV_F05.20972.20972.3 3.41E-07 16/52 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 5.66 44063 20972 3 1535.790372 512.9375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3858.1 - 165651 - - - -0.1042 - 2.86 0.559 - 400.4 1 2 0 -0.0002 14 0 0 0 2.57E+07 4.54E+06 - - - 7.5648 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.20976.20976.2 6.33E-07 14/20 K.LEDVLPLAFTR.L "sp|Q5SSJ5|HP1B3_HUMAN,tr|B0QZK4|B0QZK4_HUMAN,tr|Q5SWC8|Q5SWC8_HUMAN" 3 1272.7078 0.79 44067 20976 2 1272.714328 637.3612 Heterochromatin protein 1-binding protein 3 OS=Homo sapiens OX=9606 GN=HP1BP3 PE=1 SV=1 4.37 3858.6 - 86054.1 - - - 5.1387 - 2.583 0.369 - 741.1 1 2 0 0.0065 11 0 0 0 3.40E+06 4.33E+06 - - - 4.3315 1 230117_WJC_METTL3_WT_vs_EV_F05.20977.20977.2 0.0185 13/20 K.LEDVLPLAFTR[166.11].L "sp|Q5SSJ5|HP1B3_HUMAN,tr|B0QZK4|B0QZK4_HUMAN,tr|Q5SWC8|Q5SWC8_HUMAN" 3 1282.7161 0.79 44068 20977 2 1282.716828 642.3653 Heterochromatin protein 1-binding protein 3 OS=Homo sapiens OX=9606 GN=HP1BP3 PE=1 SV=1 4.37 3858.7 - 84294.6 - - - 0.6003 - 2.463 0.44 - 600.5 1 2 0 0.0008 11 0 0 0 3.40E+06 4.33E+06 - - - 4.729 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20979.20979.2 0.000106 20-Sep K.DFPLSGYVELR.Y sp|O75489|NDUS3_HUMAN 1 1294.6558 2.18 44070 20979 2 1294.657968 648.3352 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 4.37 3859 - 70112.4 - - - 1.7117 - 1.765 0.346 - 273.9 1 2 0 0.0022 11 0 0 0 6.96E+06 3.20E+06 - - - 3.1328 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.20980.20980.2 8.24E-05 14/22 R.LGLQNDLFSLAR[166.11].A "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1355.7437 -1 44071 20980 2 1355.743344 678.8791 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.84 3859.1 - 34736.7 - - - -0.2405 - 2.238 0.43 - 484.9 1 2 0 -0.0003 12 0 0 0 0.00E+00 0.00E+00 - - - 4.3365 1 230117_WJC_METTL3_WT_vs_EV_F05.20981.20981.2 8.99E-05 17/26 K.LFIYNPTTGEFLGR.T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1626.8406 1.39 44072 20981 2 1626.839407 814.4276 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3859.2 - 79797.6 - - - -0.729 - 2.905 0.578 - 921.6 1 2 0 -0.0012 14 0 0 0 4.61E+07 3.32E+07 - - - 5.9859 1 230117_WJC_METTL3_WT_vs_EV_F05.20982.20982.2 3.50E-06 24-Dec R.GLAFELVYSPAIK.D "sp|P78346|RPP30_HUMAN,tr|Q5VU11|Q5VU11_HUMAN,tr|Q5VU10|Q5VU10_HUMAN" 3 1406.781 -1 44073 20982 2 1406.782898 704.3978 Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1 6 3859.4 - 28137.5 - - - 1.3826 - 2.214 0.475 - 307.6 1 2 0 0.0019 13 0 0 0 0.00E+00 0.00E+00 - - - 4.5886 1 230117_WJC_METTL3_WT_vs_EV_F05.20983.20983.2 2.39E-06 24-Oct R.GLAFELVYSPAIK[136.11].D "sp|P78346|RPP30_HUMAN,tr|Q5VU11|Q5VU11_HUMAN,tr|Q5VU10|Q5VU10_HUMAN" 3 1414.7952 -1 44074 20983 2 1414.79667 708.4049 Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1 6 3859.5 - 41016 - - - 1.0722 - 2.11 0.497 - 328.8 1 2 0 0.0015 13 0 0 0 0.00E+00 0.00E+00 - - - 4.6278 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.20990.20990.2 3.71E-05 20-Sep R.DSLIFLVDASK.A sp|P12956|XRCC6_HUMAN 1 1206.6496 0.94 44080 20990 2 1206.65095 604.3321 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.21 3860.1 - 541804 - - - 1.1155 - 1.8 0.418 - 240.2 1 2 0 0.0013 11 0 0 0 4.88E+07 5.16E+07 - - - 3.718 0.9912 230117_WJC_METTL3_WT_vs_EV_F05.20994.20994.2 0.09 28-Mar R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 3.22 44082 20994 2 1700.899992 851.4565 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3860.6 - 2.91E+07 - - - 0.876 - 0.696 0.331 - 25.9 1 2 0 0.0015 15 0 0 0 4.74E+08 1.48E+08 - - - 0.5943 1 230117_WJC_METTL3_WT_vs_EV_F05.20995.20995.2 9.96E-09 26-Nov K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 14.8 44083 20995 2 1621.814732 811.9149 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3860.6 - 5.95E+06 - - - -0.3478 - 2.337 0.665 - 257.9 1 2 0 -0.0006 14 0 0 0 8.20E+08 5.54E+07 - - - 6.0827 1 230117_WJC_METTL3_WT_vs_EV_F05.20996.20996.2 4.17E-07 15/28 R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 3.22 44084 20996 2 1710.90668 856.4607 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3860.6 - 1.20E+07 - - - -0.0538 - 3.175 0.572 - 475.4 1 2 0 -0.0001 15 0 0 0 4.74E+08 1.48E+08 - - - 6.1061 1 230117_WJC_METTL3_WT_vs_EV_F05.21000.21000.3 7.65E-08 13/56 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 5.43 44088 21000 3 1700.899916 567.9734 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3860.8 - 6.05E+06 - - - 0.8313 - 2.732 0.525 - 265.3 1 2 0 0.0014 15 0 0 0 1.06E+08 1.96E+07 - - - 7.0153 1 230117_WJC_METTL3_WT_vs_EV_F05.21003.21003.2 1.47E-05 22-Sep R.LEGLTDEINFLR[166.11].Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1428.7488 1.76 44091 21003 2 1428.748207 715.3817 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3860.9 - 3.56E+06 - - - -0.4255 - 2.068 0.538 - 355.2 1 2 0 -0.0006 12 0 0 0 3.83E+07 2.18E+07 - - - 4.9262 1 230117_WJC_METTL3_WT_vs_EV_F05.21005.21005.2 4.73E-06 17/28 K.VSALDLAVLDQVEAR.L "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 6 1597.8675 3.7 44093 21005 2 1597.868173 799.941 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.03 3861 - 3.16E+06 - - - 0.3987 - 3.223 0.488 - 1188.6 1 2 0 0.0006 15 0 0 0 1.16E+07 3.13E+06 - - - 5.5224 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21007.21007.2 2.50E-06 26-Sep R.VFGAPEVLENLEVK[136.11].S sp|Q8TEM1|PO210_HUMAN 1 1550.8436 1.68 44095 21007 2 1550.847659 776.4291 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.25 3861.1 - 2.26E+06 - - - 2.6431 - 1.944 0.468 - 194.7 1 2 0 0.0041 14 0 0 0 1.12E+07 6.69E+06 - - - 4.1645 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.21010.21010.2 0.000284 20-Sep K.DFPLSGYVELR.Y sp|O75489|NDUS3_HUMAN 1 1294.6558 2.18 44098 21010 2 1294.655334 648.3352 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 4.37 3861.3 - 1.26E+06 - - - -0.3229 - 1.708 0.328 - 276.8 1 2 0 -0.0004 11 0 0 0 6.96E+06 3.20E+06 - - - 2.9117 1 230117_WJC_METTL3_WT_vs_EV_F05.21013.21013.2 9.23E-08 13/26 K.TFAPEEISAMVLTK[136.11].M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1543.8047 3.82 44099 21013 2 1543.807065 772.9096 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3861.7 - 1.83E+06 - - - 1.5112 - 2.337 0.576 - 470.5 1 2 0 0.0023 14 0 0 0 1.11E+08 2.91E+07 - - - 5.4248 0.999 230117_WJC_METTL3_WT_vs_EV_F05.21014.21014.2 0.00144 18-Oct K.FSLFAGGMLR.V sp|Q9BVK6|TMED9_HUMAN 1 1097.5692 1.02 44100 21014 2 1097.567676 549.7919 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 9.75 3861.8 - 949819 - - - -1.3758 - 2.11 0.421 - 389.5 1 2 0 -0.0015 10 0 0 0 1.63E+07 1.60E+07 - - - 4.2343 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21015.21015.3 8.30E-08 17/52 K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 13.69 44101 21015 3 1621.812323 541.6124 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3861.9 - 901776 - - - -1.8331 - 2.679 0.55 - 375.2 1 2 0 -0.003 14 0 0 0 2.04E+08 1.49E+07 - - - 7.29 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.21016.21016.2 0.00191 18-Oct K.FEELNMDLFR.S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1312.6122 3.06 44102 21016 2 1312.611542 657.3134 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.14 3862 - 758871 - - - -0.4807 - 2.179 0.408 - 359.7 1 2 0 -0.0006 10 0 0 0 3.70E+07 1.21E+07 - - - 4.2283 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.21019.21019.2 0.00193 14-Sep R.FPLFGGWK.T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 950.5014 1.66 44105 21019 2 950.500548 476.258 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3862.4 - 414817 - - - -0.9216 - 1.598 0.358 - 265.4 1 2 0 -0.0009 8 0 0 0 4.45E+07 2.69E+07 - - - 3.0986 0.9935 230117_WJC_METTL3_WT_vs_EV_F05.21020.21020.2 0.221 16-Jul K.ATIEDILFK[136.11].A "sp|Q13888|TF2H2_HUMAN,sp|Q6P1K8|T2H2L_HUMAN,tr|D6RIT7|D6RIT7_HUMAN,tr|D6RGC9|D6RGC9_HUMAN,tr|D6RAW1|D6RAW1_HUMAN,tr|D6RJD3|D6RJD3_HUMAN,tr|D6RID8|D6RID8_HUMAN,tr|R4GMS9|R4GMS9_HUMAN" 8 1056.5947 2.84 44106 21020 2 1056.595159 529.3046 General transcription factor IIH subunit 2 OS=Homo sapiens OX=9606 GN=GTF2H2 PE=1 SV=1 4.37 3862.6 - 363059 - - - 0.4704 - 1.478 0.099 - 125 1 2 0 0.0005 9 0 0 0 1.56E+07 5.48E+06 - - - 0.9023 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.21021.21021.2 8.53E-05 22-Oct R.VTGVPLSYLLSR.G "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1303.75 4.82 44107 21021 2 1303.749176 652.8823 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.72 3862.7 - 343666 - - - -0.6221 - 1.785 0.396 - 234.7 1 2 0 -0.0008 12 0 0 0 5.39E+06 1.12E+06 - - - 3.4901 1 230117_WJC_METTL3_WT_vs_EV_F05.21023.21023.2 1.21E-05 24-Oct R.APLPDLYPFGTMR.G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1476.7435 1.62 44109 21023 2 1476.741367 739.379 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3862.9 - 313308 - - - -1.4593 - 2.08 0.512 - 313.9 1 2 0 -0.0022 13 0 0 0 1.92E+07 1.19E+07 - - - 4.7016 1 230117_WJC_METTL3_WT_vs_EV_F05.21024.21024.2 0.000603 13/26 R.VLLATLSIPITPER.T sp|Q14152|EIF3A_HUMAN 1 1521.913 0.97 44110 21024 2 1521.913872 761.9638 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3863.1 - 289699 - - - 0.5533 - 2.482 0.469 - 337.2 1 2 0 0.0008 14 0 0 0 4.88E+07 5.04E+07 - - - 4.786 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.21025.21025.2 0.000407 18-Oct R.MIYLQTLLAK.E sp|P11274|BCR_HUMAN 1 1192.689 3.41 44111 21025 2 1192.688079 597.3518 Breakpoint cluster region protein OS=Homo sapiens OX=9606 GN=BCR PE=1 SV=2 8.34 3863.2 - 279786 - - - -0.7445 - 1.657 0.388 - 263.6 1 2 0 -0.0009 10 0 0 0 3.55E+06 1.04E+06 - - - 3.3161 0.9681 230117_WJC_METTL3_WT_vs_EV_F05.21027.21027.2 0.0303 14-Jun R.EGLLAIFK[136.11].S "sp|P35222|CTNB1_HUMAN,sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|C9J826|C9J826_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 15 897.5415 6.78 44113 21027 2 897.539017 449.778 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 6.1 3863.5 - 242174 - - - -2.7709 - 1.269 0.19 - 94.3 1 2 0 -0.0025 8 0 0 0 3.54E+07 5.23E+06 - - - 1.162 1 230117_WJC_METTL3_WT_vs_EV_F05.21029.21029.2 0.000675 14/24 R.APLPDLYPFGTMR[166.11].G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1486.7518 1.38 44115 21029 2 1486.753943 744.3832 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3863.7 - 240244 - - - 1.4468 - 2.394 0.492 - 645.7 1 2 0 0.0022 13 0 0 0 9.58E+06 6.95E+06 - - - 4.9147 1 230117_WJC_METTL3_WT_vs_EV_F05.21031.21031.2 1.20E-06 28-Dec K.LLDTVDDMLANDIAR.L "sp|Q9H4M9|EHD1_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 3 1673.8294 4.28 44117 21031 2 1673.828185 837.922 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 3.77 3864 - 209633 - - - -0.7474 - 2.515 0.564 - 362.6 1 2 0 -0.0013 15 0 0 0 3.48E+06 8.12E+05 - - - 5.4738 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.21032.21032.2 0.00352 22-Aug K.VPDGMVGFIIGR[166.11].G "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 3 1269.6779 2.63 44118 21032 2 1269.677806 635.8462 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 5.81 3864.1 - 205128 - - - -0.0725 - 1.427 0.365 - 101 1 2 0 -0.0001 12 0 0 0 5.56E+06 2.11E+06 - - - 2.6724 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.21034.21034.3 0.000709 Nov-44 R.LLALLDALASHK.A "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 1263.7551 1.25 44119 21034 3 1263.753074 422.259 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6.74 3864.3 - 1.12E+06 - - - -1.5818 - 2.529 0.297 - 234.3 1 2 0 -0.002 12 0 0 0 4.97E+06 3.98E+06 - - - 4.4225 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.21036.21036.2 0.000766 20-Nov K.SGAYLIPLLER.L "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1230.6972 1.28 44121 21036 2 1230.694913 616.3559 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.72 3864.5 - 6.14E+06 - - - -1.877 - 2.122 0.309 - 452.8 1 2 0 -0.0023 11 0 0 0 2.64E+08 2.07E+08 - - - 3.3579 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21037.21037.2 1.61E-05 20-Oct K.SGAYLIPLLER[166.11].L "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1240.7055 1.28 44122 21037 2 1240.706812 621.36 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.72 3864.6 - 5.37E+06 - - - 1.0631 - 1.937 0.276 - 310.8 1 2 0 0.0013 11 0 0 0 2.64E+08 2.07E+08 - - - 2.8677 0.998 230117_WJC_METTL3_WT_vs_EV_F05.21038.21038.2 0.00013 20-Oct R.GVTFLFPIQAK.T sp|Q9NR30|DDX21_HUMAN 1 1219.6965 0.96 44123 21038 2 1219.694314 610.8555 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3864.6 - 4.26E+06 - - - -1.7881 - 1.969 0.338 - 409.7 1 2 0 -0.0022 11 0 0 0 1.28E+08 1.34E+08 - - - 3.3697 0.9975 230117_WJC_METTL3_WT_vs_EV_F05.21039.21039.2 0.00438 14-Aug K.FYSFLVLK.K "sp|Q9H4I0|RD21L_HUMAN,sp|O60216|RAD21_HUMAN,tr|A0A804HJ87|A0A804HJ87_HUMAN,tr|E5RI01|E5RI01_HUMAN,tr|E5RG18|E5RG18_HUMAN,tr|E5RFZ5|E5RFZ5_HUMAN" 6 1015.5743 3.28 44124 21039 2 1015.572633 508.7944 Double-strand-break repair protein rad21-like protein 1 OS=Homo sapiens OX=9606 GN=RAD21L1 PE=2 SV=3 8.59 3864.7 - 3.71E+06 - - - -1.5971 - 1.326 0.411 - 148 1 2 0 -0.0016 8 0 0 0 3.19E+07 9.71E+06 - - - 2.9271 0.9894 230117_WJC_METTL3_WT_vs_EV_F05.21040.21040.2 0.000131 14-Sep R.FPLFGGWK[136.11].T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 958.5156 1.66 44125 21040 2 958.511442 480.2651 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3864.8 - 2.25E+06 - - - -4.363 - 1.734 0.353 - 310 1 2 0 -0.0042 8 0 0 0 4.69E+07 2.83E+07 - - - 3.307 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.21042.21042.2 0.0337 14-Aug R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 15.87 44127 21042 2 1000.557604 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3865 - 937723 - - - -1.728 - 1.846 0.294 - 213.5 1 2 0 -0.0017 8 0 0 0 1.06E+07 6.66E+05 - - - 3.0608 1 230117_WJC_METTL3_WT_vs_EV_F05.21044.21044.2 5.86E-07 26-Nov R.ILGIPVIVTEQYPK[136.11].G "sp|Q96CN7|ISOC1_HUMAN,tr|D6RGE2|D6RGE2_HUMAN" 2 1576.932 1.24 44129 21044 2 1576.932891 789.4733 Isochorismatase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ISOC1 PE=1 SV=3 6 3865.3 - 393805 - - - 0.5771 - 2.226 0.544 - 285.6 1 2 0 0.0009 14 0 0 0 3.02E+06 2.44E+06 - - - 5.0668 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21045.21045.2 0.00031 20-Sep K.LSDLDYMQFIR[166.11].L sp|P82933|RT09_HUMAN 1 1409.6889 1.28 44130 21045 2 1409.690783 705.8517 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.21 3865.4 - 353086 - - - 1.3663 - 2.403 0.304 - 405.4 1 2 0 0.0019 11 0 0 0 1.27E+07 9.95E+06 - - - 3.6575 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.21056.21056.2 0.000888 20-Nov R.GVTFLFPIQAK[136.11].T sp|Q9NR30|DDX21_HUMAN 1 1227.7107 0.96 44137 21056 2 1227.709318 614.8626 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3866.7 - 1.09E+07 - - - -1.1216 - 2.131 0.309 - 424.4 1 2 0 -0.0014 11 0 0 0 1.28E+08 1.34E+08 - - - 3.3696 1 230117_WJC_METTL3_WT_vs_EV_F05.21057.21057.2 6.51E-07 16/26 R.VLLATLSIPITPER[166.11].T sp|Q14152|EIF3A_HUMAN 1 1531.9213 0.97 44138 21057 2 1531.922166 766.9679 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3866.9 - 2.82E+06 - - - 0.5653 - 3.068 0.496 - 824.7 1 2 0 0.0009 14 0 0 0 4.88E+07 5.04E+07 - - - 5.5173 0.9907 230117_WJC_METTL3_WT_vs_EV_F05.21058.21058.2 0.000153 18-Sep R.YVLGMQELFR.G "sp|Q96J01|THOC3_HUMAN,tr|D6RGZ2|D6RGZ2_HUMAN" 2 1254.6431 1.01 44139 21058 2 1254.63679 628.3288 THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1 6 3867 - 2.54E+06 - - - -5.0126 - 1.761 0.502 - 240.2 1 2 0 -0.0063 10 0 0 0 1.46E+07 1.46E+07 - - - 4.3263 1 230117_WJC_METTL3_WT_vs_EV_F05.21061.21061.2 0.00118 14/20 K.LSDLDYMQFIR.L sp|P82933|RT09_HUMAN 1 1399.6806 1.28 44142 21061 2 1399.681159 700.8476 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.21 3867.4 - 1.09E+06 - - - 0.4087 - 3.038 0.418 - 1218.3 1 2 0 0.0006 11 0 0 0 1.27E+07 9.95E+06 - - - 5.1342 0.8701 230117_WJC_METTL3_WT_vs_EV_F05.21065.21065.2 0.106 16-Aug N.ILLVDEIMR.A "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1100.6264 0.16 44146 21065 2 1100.626693 551.3205 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 4.37 3867.9 - 698709 - - - 0.2962 - 1.72 0.188 - 177.1 1 1 0 0.0003 9 0 0 0 9.03E+06 5.50E+07 - - - 1.9984 1 230117_WJC_METTL3_WT_vs_EV_F05.21066.21066.2 0.000203 16/26 R.DYGVLLEGSGLALR[166.11].G sp|P30048|PRDX3_HUMAN 1 1471.791 0.81 44147 21066 2 1471.788243 736.9028 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 4.37 3868 - 579024 - - - -1.8827 - 2.914 0.549 - 836.6 1 2 0 -0.0028 14 0 0 0 7.97E+06 9.84E+06 - - - 5.779 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.21069.21069.3 0.0061 13/44 R.LLALLDALASHK[136.11].A "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 1271.7693 1.25 44150 21069 3 1271.767801 424.9304 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6.74 3868.4 - 450097 - - - -1.1574 - 2.166 0.352 - 258 1 2 0 -0.0015 12 0 0 0 4.97E+06 3.98E+06 - - - 4.6064 1 230117_WJC_METTL3_WT_vs_EV_F05.21070.21070.2 4.35E-06 26-Oct R.ILGIPVIVTEQYPK.G "sp|Q96CN7|ISOC1_HUMAN,tr|D6RGE2|D6RGE2_HUMAN" 2 1568.9178 1.25 44151 21070 2 1568.922209 785.4662 Isochorismatase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ISOC1 PE=1 SV=3 6 3868.5 - 407332 - - - 2.8223 - 1.837 0.554 - 253.9 1 2 0 0.0044 14 0 0 0 3.04E+06 2.44E+06 - - - 4.6575 0.998 230117_WJC_METTL3_WT_vs_EV_F05.21071.21071.2 0.0509 14-Jun R.SFTNQIIL.- "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIM4|A0A804HIM4_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 3 934.5124 - 44152 21071 2 934.511581 468.2635 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 5.24 3868.7 - 375555 - - - -0.8582 - 1.317 0.375 - 66.1 1 2 0 -0.0008 8 0 0 0 - - - - - 2.641 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.21072.21072.2 0.638 20-Jul K.IALGIPLPEIK.N "sp|P31327|CPSM_HUMAN,tr|A0A669KBF2|A0A669KBF2_HUMAN" 2 1162.7325 1.86 44153 21072 2 1162.73285 582.3735 "Carbamoyl-phosphate synthase [ammonia], mitochondrial OS=Homo sapiens OX=9606 GN=CPS1 PE=1 SV=2" 6 3868.8 - 327350 - - - 0.2615 - 1.629 0.185 - 118.6 1 2 0 0.0003 11 0 0 0 3.55E+06 1.91E+06 - - - 1.7274 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.21078.21078.2 0.000387 16-Jul K.TTPLLSFLK[136.11].N sp|Q9BZI7|REN3B_HUMAN 1 1026.6205 0.87 44158 21078 2 1026.620676 514.3175 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 8.41 3869.4 - 2.76E+06 - - - 0.188 - 1.626 0.395 - 206.3 1 2 0 0.0002 9 0 0 0 3.39E+07 3.92E+07 - - - 3.3648 1 230117_WJC_METTL3_WT_vs_EV_F05.21082.21082.2 2.81E-06 14/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 58.32 44162 21082 2 1343.610904 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3869.7 - 1.24E+06 - - - -0.4153 - 2.817 0.545 - 724.3 1 1 0 -0.0006 10 0 0 0 9.02E+06 1.55E+05 - - - 5.9571 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21089.21089.2 0.000665 26-Sep R.DYGVLLEGSGLALR.G sp|P30048|PRDX3_HUMAN 1 1461.7827 0.7 44167 21089 2 1461.783662 731.8986 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 4.37 3870.6 - 1.28E+06 - - - 0.628 - 1.729 0.447 - 207.5 1 2 0 0.0009 14 0 0 0 7.97E+06 1.13E+07 - - - 3.7163 1 230117_WJC_METTL3_WT_vs_EV_F05.21094.21094.2 3.47E-05 24-Oct R.ELPTAFDYVEFTR[166.11].S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1596.7699 1.17 44172 21094 2 1596.773004 799.3922 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.14 3871 - 716883 - - - 1.9164 - 2.327 0.529 - 386.4 1 2 0 0.0031 13 0 0 0 1.63E+07 1.40E+07 - - - 5.1149 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.21095.21095.2 0.0265 20-Aug K.NVPGLAILLSK.D sp|Q9BUL9|RPP25_HUMAN 1 1123.6965 1.16 44173 21095 2 1123.695749 562.8555 Ribonuclease P protein subunit p25 OS=Homo sapiens OX=9606 GN=RPP25 PE=1 SV=1 8.75 3871.1 - 576642 - - - -0.6639 - 1.413 0.294 - 128.8 1 2 0 -0.0007 11 0 0 0 9.29E+06 8.00E+06 - - - 2.1475 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21096.21096.2 8.16E-05 18-Oct K.C[160.03]PFLIPFETR.Q "sp|Q9ULT8|HECD1_HUMAN,tr|H0YJD4|H0YJD4_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN" 3 1278.6431 2.63 44174 21096 2 1278.643021 640.3288 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 5.99 3871.3 - 343450 - - - -0.0461 - 2.086 0.438 - 455.9 1 2 0 -0.0001 10 0 0 0 2.31E+06 8.78E+05 - - - 4.3284 0.9982 230117_WJC_METTL3_WT_vs_EV_F05.21101.21101.2 0.0875 22-May R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 44178 21101 2 1603.763944 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3871.9 - 3.50E+08 - - - 0.0025 - 1.2 0.362 - 66.2 1 2 0 0 12 0 0 0 2.25E+09 0.00E+00 - - - 2.1944 1 230117_WJC_METTL3_WT_vs_EV_F05.21104.21104.2 1.70E-08 22-Dec K.VDALMDEINFMK.M "sp|P13647|K2C5_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 2 1424.668 645.46 44180 21104 2 1424.666985 713.3413 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.03 3872.2 - 915467 - - - -0.6935 - 2.677 0.62 - 420 1 2 0 -0.001 12 0 0 0 5.94E+07 9.20E+04 - - - 6.2109 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21105.21105.2 0.00026 14-Aug R.GFVFITFK[136.11].E "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 965.5466 0.83 44181 21105 2 965.547029 483.7806 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3872.3 - 1.95E+06 - - - 0.4547 - 1.61 0.458 - 278.3 1 2 0 0.0004 8 0 0 0 3.48E+07 4.21E+07 - - - 3.86 1 230117_WJC_METTL3_WT_vs_EV_F05.21107.21107.2 6.14E-05 13/24 R.ELYAFFGDSLATR.F sp|Q9Y6J9|TAF6L_HUMAN 1 1488.7249 1.11 44183 21107 2 1488.722777 745.3697 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4.37 3872.6 - 470416 - - - -1.4227 - 2.403 0.54 - 578.8 1 2 0 -0.0021 13 0 0 0 9.57E+06 8.61E+06 - - - 5.2789 0.9837 230117_WJC_METTL3_WT_vs_EV_F05.21109.21109.2 3.26 20-Aug K.AIGFVMVDAKK.E sp|O14958|CASQ2_HUMAN 1 1177.6529 1.27 44185 21109 2 1177.651531 589.8337 Calsequestrin-2 OS=Homo sapiens OX=9606 GN=CASQ2 PE=1 SV=2 8.64 3872.8 - 323245 - - - -1.1761 - 1.614 0.078 - 162.7 1 2 0 -0.0014 11 0 0 0 4.83E+06 3.79E+06 - - - 0.9117 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.21110.21110.2 0.00387 20-Sep R.SIFTGLMIDPR.T sp|Q8IWA0|WDR75_HUMAN 1 1248.6536 1.94 44186 21110 2 1248.653676 625.3341 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 5.55 3872.9 - 320774 - - - 0.0256 - 1.666 0.369 - 202.4 1 2 0 0 11 0 0 0 1.06E+07 5.48E+06 - - - 3.1472 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21112.21112.2 0.000289 22-Nov K.LTAYAMTIPFVR.Q "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1381.7428 1.07 44188 21112 2 1381.742906 691.8787 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 3873.2 - 228645 - - - 0.0818 - 2.222 0.438 - 512.1 1 2 0 0.0001 12 0 0 0 6.53E+06 6.12E+06 - - - 4.3768 1 230117_WJC_METTL3_WT_vs_EV_F05.21114.21114.2 4.21E-05 22-Dec K.LTAYAMTIPFVR[166.11].Q "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1391.7511 1.09 44190 21114 2 1391.751161 696.8828 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 3873.5 - 212721 - - - 0.0704 - 2.293 0.484 - 639.7 1 2 0 0.0001 12 0 0 0 6.53E+06 6.01E+06 - - - 4.7993 1 230117_WJC_METTL3_WT_vs_EV_F05.21118.21118.2 3.98E-09 18/26 R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 18.41 44194 21118 2 1581.80829 791.9109 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3874 - 146521 - - - 0.6613 - 3.218 0.66 - 855.9 1 2 0 0.001 14 0 0 0 2.27E+07 1.23E+06 - - - 6.8484 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.21124.21124.3 0.00142 Sep-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 44199 21124 3 1603.765595 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3874.7 - 2.72E+07 - - - 1.0319 - 2.061 0.395 - 122.8 1 2 0 0.0017 12 0 0 0 1.53E+08 0.00E+00 - - - 4.948 0.9943 230117_WJC_METTL3_WT_vs_EV_F05.21126.21126.2 1.05E-05 24-Oct R.LLSFSPEEFPTLK[136.11].A sp|Q5JSZ5|PRC2B_HUMAN 1 1514.8112 -1 44201 21126 2 1514.819292 758.4129 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3874.8 - 9.71E+06 - - - 5.3439 - 1.841 0.307 - 236.5 1 2 0 0.0081 13 0 0 0 0.00E+00 0.00E+00 - - - 2.8723 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.21127.21127.2 0.000825 18-Aug R.LLEVYDQLFK.S "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1266.686 2.37 44202 21127 2 1266.683768 634.3503 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3874.9 - 5.53E+06 - - - -1.7542 - 1.892 0.464 - 181.6 1 2 0 -0.0022 10 0 0 0 1.33E+07 5.62E+06 - - - 4.2472 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21129.21129.3 0.000142 Sep-40 R.SIIGMIDMFHK.Y "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1290.6464 872.71 44204 21129 3 1290.644541 431.2228 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.46 3875 - 4.35E+06 - - - -1.4791 - 1.918 0.475 - 79.7 1 2 0 -0.0019 11 0 0 0 8.29E+06 9.50E+03 - - - 5.6854 0.9938 230117_WJC_METTL3_WT_vs_EV_F05.21133.21133.3 0.163 Jul-52 R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 96 44208 21133 3 1581.805564 528.2764 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3875.2 - 3.16E+06 - - - -1.0621 - 1.735 0.225 - 83.8 1 2 0 -0.0017 14 0 0 0 4.62E+06 4.81E+04 - - - 2.5124 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.21134.21134.2 0.144 20-Sep K.NVPGLAILLSK[136.11].D sp|Q9BUL9|RPP25_HUMAN 1 1131.7107 1.15 44209 21134 2 1131.710367 566.8626 Ribonuclease P protein subunit p25 OS=Homo sapiens OX=9606 GN=RPP25 PE=1 SV=1 8.75 3875.3 - 2.47E+06 - - - -0.2898 - 1.621 0.28 - 210 1 2 0 -0.0003 11 0 0 0 9.51E+06 8.25E+06 - - - 2.4157 1 230117_WJC_METTL3_WT_vs_EV_F05.21135.21135.2 1.73E-09 22-Dec K.VMEETLSYLLGR.K "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN,tr|A0A5F9ZH78|A0A5F9ZH78_HUMAN" 3 1409.7225 -1 44210 21135 2 1409.723992 705.8685 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 4.53 3875.4 - 2.43E+06 - - - 1.0924 - 2.545 0.666 - 603.5 1 2 0 0.0015 12 0 0 0 0.00E+00 0.00E+00 - - - 6.4174 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.21136.21136.2 0.000729 16-Jul K.AFVPAILFK.D sp|Q9HAU5|RENT2_HUMAN 1 1004.6059 1.13 44211 21136 2 1004.60461 503.3102 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3875.5 - 2.26E+06 - - - -1.2731 - 1.572 0.403 - 159.1 1 2 0 -0.0013 9 0 0 0 7.38E+06 6.50E+06 - - - 3.3258 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.21137.21137.2 9.99E-05 16-Sep K.AFVPAILFK[136.11].D sp|Q9HAU5|RENT2_HUMAN 1 1012.6201 1.13 44212 21137 2 1012.618101 507.3173 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3875.5 - 2.07E+06 - - - -1.9632 - 1.844 0.442 - 321.7 1 2 0 -0.002 9 0 0 0 7.38E+06 6.50E+06 - - - 4.0754 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.21139.21139.2 0.0161 26-Jul K.TGAAGAEALSLLLK.R "sp|Q9P2N6|KANL3_HUMAN,tr|C9J5A4|C9J5A4_HUMAN,tr|A0A590UJ53|A0A590UJ53_HUMAN" 3 1313.7555 -1 44214 21139 2 1313.754885 657.885 KAT8 regulatory NSL complex subunit 3 OS=Homo sapiens OX=9606 GN=KANSL3 PE=1 SV=2 5.66 3875.7 - 1.35E+06 - - - -0.443 - 1.256 0.342 - 151.8 1 2 0 -0.0006 14 0 0 0 0.00E+00 0.00E+00 - - - 2.1388 1 230117_WJC_METTL3_WT_vs_EV_F05.21141.21141.2 3.08E-07 13/28 K.LLMSEDYFTQAMEVK.A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1803.8423 -1 44216 21141 2 1803.840976 902.9284 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.14 3875.9 - 1.06E+06 - - - -0.739 - 3.023 0.652 - 343.1 1 2 0 -0.0013 15 0 0 0 0.00E+00 0.00E+00 - - - 6.576 1 230117_WJC_METTL3_WT_vs_EV_F05.21142.21142.2 1.08E-07 15/28 K.LLMSEDYFTQAMEVK[136.11].A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1811.8565 0.84 44217 21142 2 1811.850005 906.9355 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.14 3876 - 741712 - - - -3.5897 - 3.23 0.701 - 677 1 2 0 -0.0065 15 0 0 0 1.86E+06 2.23E+06 - - - 7.0991 1 230117_WJC_METTL3_WT_vs_EV_F05.21152.21152.2 5.31E-08 14/26 R.ILSVQGTEPLVLFK.E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1542.9021 1.33 44226 21152 2 1542.906673 772.4583 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3877.5 - 486469 - - - 2.9438 - 2.674 0.603 - 634.9 1 2 0 0.0045 14 0 0 0 1.20E+07 9.02E+06 - - - 5.9616 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.21153.21153.2 0.0033 16-Sep R.WLGDLILSK[136.11].S "sp|O75530|EED_HUMAN,tr|A0A5F9ZI63|A0A5F9ZI63_HUMAN" 2 1051.6157 1.03 44227 21153 2 1051.619095 526.8151 Polycomb protein EED OS=Homo sapiens OX=9606 GN=EED PE=1 SV=2 5.84 3877.6 - 458859 - - - 3.1979 - 1.804 0.4 - 288.9 1 2 0 0.0034 9 0 0 0 4.89E+06 4.74E+06 - - - 3.7013 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.21154.21154.2 1.10E-05 26-Sep R.ILSVQGTEPLVLFK[136.11].E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1550.9163 1.33 44228 21154 2 1550.922207 776.4654 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3877.7 - 434071 - - - 3.7887 - 2.088 0.484 - 227.1 1 2 0 0.0059 14 0 0 0 1.20E+07 9.02E+06 - - - 4.4615 1 230117_WJC_METTL3_WT_vs_EV_F05.21169.21169.2 2.73E-05 17/26 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.46 44242 21169 2 1672.881882 837.4479 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3879.4 - 2.26E+06 - - - 0.3921 - 3.23 0.583 - 1236.6 1 2 0 0.0007 14 0 0 0 8.27E+07 1.80E+08 - - - 6.2891 1 230117_WJC_METTL3_WT_vs_EV_F05.21170.21170.2 9.23E-06 14/26 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.46 44243 21170 2 1662.871566 832.4438 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3879.4 - 948594 - - - -0.8359 - 3.037 0.567 - 839.6 1 2 0 -0.0014 14 0 0 0 8.27E+07 1.80E+08 - - - 6.0161 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.21172.21172.2 0.232 20-Aug R.LLEFELAQLTK[136.11].Q "sp|Q13464|ROCK1_HUMAN,tr|A0A0U1RQV4|A0A0U1RQV4_HUMAN" 2 1311.753 0.6 44245 21172 2 1311.751037 656.8838 Rho-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=ROCK1 PE=1 SV=1 4.53 3879.6 - 396151 - - - -1.4614 - 1.782 0.308 - 158.7 1 2 0 -0.0019 11 0 0 0 3.36E+06 5.62E+06 - - - 2.8782 1 230117_WJC_METTL3_WT_vs_EV_F05.21179.21179.2 1.04E-05 15/24 R.LLSFSPEEFPTLK.A sp|Q5JSZ5|PRC2B_HUMAN 1 1506.797 1.55 44250 21179 2 1506.799561 754.4058 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3880.4 - 1.29E+07 - - - 1.7016 - 2.553 0.546 - 713.9 1 2 0 0.0026 13 0 0 0 5.31E+07 3.43E+07 - - - 5.4785 1 230117_WJC_METTL3_WT_vs_EV_F05.21180.21180.3 3.97E-09 20/52 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.57 44251 21180 3 1672.884457 558.6344 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3880.5 - 6.41E+06 - - - 1.9314 - 3.108 0.551 - 617.6 1 2 0 0.0032 14 0 0 0 4.03E+07 7.07E+07 - - - 7.6958 1 230117_WJC_METTL3_WT_vs_EV_F05.21181.21181.2 5.02E-07 17/26 K.LFSLELVDESGEIR[166.11].A sp|P27694|RFA1_HUMAN 1 1615.8333 0.1 44252 21181 2 1615.830874 808.9239 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4 3880.6 - 5.05E+06 - - - -1.4847 - 3.084 0.535 - 1277.6 1 2 0 -0.0024 14 0 0 0 5.80E+06 5.67E+07 - - - 5.818 1 230117_WJC_METTL3_WT_vs_EV_F05.21182.21182.2 6.78E-12 17/24 R.FGQDIISPLLSVK[136.11].E "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V414|A0A7I2V414_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|J3KNG4|J3KNG4_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|G3V5F3|G3V5F3_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|A0A7I2V4B9|A0A7I2V4B9_HUMAN,tr|H0YJY1|H0YJY1_HUMAN,tr|H0YJS6|H0YJS6_HUMAN,tr|G3V363|G3V363_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2V5R9|A0A7I2V5R9_HUMAN,tr|G3V4I1|G3V4I1_HUMAN,tr|A0A7I2V3Y3|A0A7I2V3Y3_HUMAN" 24 1423.8166 1.6 44253 21182 2 1423.818778 712.9156 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 5.84 3880.8 - 4.13E+06 - - - 1.5178 - 3.318 0.65 - 1134.9 1 2 0 0.0022 13 0 0 0 1.82E+07 1.14E+07 - - - 6.9194 1 230117_WJC_METTL3_WT_vs_EV_F05.21184.21184.2 2.23E-07 22-Nov R.LIMNYLVTEGFK[136.11].E sp|Q9NWU2|GID8_HUMAN 1 1434.7672 0.86 44255 21184 2 1434.768854 718.3909 Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1 6 3881 - 2.36E+06 - - - 1.1361 - 2.269 0.551 - 293.4 1 2 0 0.0016 12 0 0 0 1.03E+07 1.19E+07 - - - 5.266 1 230117_WJC_METTL3_WT_vs_EV_F05.21185.21185.2 0.000213 18-Oct K.DAITQALFLR.E sp|Q9UNX4|WDR3_HUMAN 1 1146.6397 1.13 44256 21185 2 1146.642067 574.3271 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.84 3881.1 - 1.94E+06 - - - 2.0573 - 2.378 0.491 - 286.7 1 2 0 0.0024 10 0 0 0 2.58E+07 2.29E+07 - - - 5.0848 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21186.21186.2 0.0014 18-Sep K.DAITQALFLR[166.11].E sp|Q9UNX4|WDR3_HUMAN 1 1156.648 1.13 44257 21186 2 1156.648714 579.3313 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.84 3881.3 - 1.91E+06 - - - 0.6363 - 2.272 0.319 - 225.1 1 2 0 0.0007 10 0 0 0 2.58E+07 2.29E+07 - - - 3.6876 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.21187.21187.2 0.00121 22-Nov R.GLFIIDPNGVIK.H sp|P30048|PRDX3_HUMAN 1 1284.7442 2.04 44258 21187 2 1284.7479 643.3794 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3881.4 - 1.65E+06 - - - 2.9002 - 2.023 0.258 - 301.7 1 2 0 0.0037 12 0 0 0 6.42E+07 3.14E+07 - - - 2.7993 1 230117_WJC_METTL3_WT_vs_EV_F05.21188.21188.2 0.000389 13/24 K.DAAIYLVTSLASK.A sp|P55060|XPO2_HUMAN 1 1350.7395 1.02 44259 21188 2 1350.741034 676.377 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.83 3881.5 - 1.17E+06 - - - 1.149 - 2.663 0.464 - 531.5 1 2 0 0.0016 13 0 0 0 1.23E+07 1.21E+07 - - - 4.9814 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21190.21190.2 0.00012 13/22 R.GLFIIDPNGVIK[136.11].H sp|P30048|PRDX3_HUMAN 1 1292.7584 2.04 44261 21190 2 1292.760781 647.3865 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3881.8 - 845324 - - - 1.8619 - 2.225 0.32 - 430.7 1 2 0 0.0024 12 0 0 0 6.41E+07 3.14E+07 - - - 3.5081 0.9113 230117_WJC_METTL3_WT_vs_EV_F05.21191.21191.2 1.65 18-Jul R.AEVWDLDMLR.S sp|Q6P2E9|EDC4_HUMAN 1 1246.6016 1.59 44262 21191 2 1246.604454 624.3081 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 4.03 3881.9 - 664100 - - - 2.283 - 1.003 0.015 - 151.3 1 2 0 0.0028 10 0 0 0 3.73E+06 2.35E+06 - - - -0.8407 1 230117_WJC_METTL3_WT_vs_EV_F05.21195.21195.2 6.95E-06 17/30 R.LFVGNLPADITEDEFK.R sp|P23246|SFPQ_HUMAN 1 1806.904 1.09 44266 21195 2 1806.903759 904.4593 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3882.4 - 499541 - - - -0.1229 - 3.165 0.579 - 365.2 1 2 0 -0.0002 16 0 0 0 2.48E+06 2.27E+06 - - - 6.15 1 230117_WJC_METTL3_WT_vs_EV_F05.21199.21199.2 2.07E-07 13/30 R.LFVGNLPADITEDEFK[136.11].R sp|P23246|SFPQ_HUMAN 1 1814.9182 -1 44269 21199 2 1814.912438 908.4664 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3883.1 - 604513 - - - -3.1643 - 2.867 0.54 - 311.9 1 2 0 -0.0057 16 0 0 0 0.00E+00 0.00E+00 - - - 5.6171 1 230117_WJC_METTL3_WT_vs_EV_F05.21200.21200.3 2.52E-08 19/52 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.58 44270 21200 3 1662.874699 555.2983 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3883.1 - 1.01E+07 - - - 1.0482 - 3.533 0.54 - 587.4 1 2 0 0.0017 14 0 0 0 4.11E+07 7.07E+07 - - - 7.9142 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.21206.21206.3 0.000897 13/52 K.LFSLELVDESGEIR[166.11].A sp|P27694|RFA1_HUMAN 1 1615.8333 0.64 44276 21206 3 1615.833409 539.6184 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4 3883.6 - 1.48E+06 - - - 0.0842 - 2.397 0.345 - 234.7 1 2 0 0.0001 14 0 0 0 1.43E+06 2.22E+06 - - - 4.7096 1 230117_WJC_METTL3_WT_vs_EV_F05.21209.21209.2 5.06E-12 15/28 R.FYAYNPLAGGLLTGK.Y "sp|Q8NHP1|ARK74_HUMAN,sp|O43488|ARK72_HUMAN,tr|A0A499FJT0|A0A499FJT0_HUMAN,tr|H3BLU7|H3BLU7_HUMAN" 4 1583.8348 1.57 44279 21209 2 1583.835681 792.9247 Aflatoxin B1 aldehyde reductase member 4 OS=Homo sapiens OX=9606 GN=AKR7L PE=2 SV=7 8.5 3884 - 1.05E+06 - - - 0.5689 - 2.992 0.697 - 695.8 1 2 0 0.0009 15 0 0 0 6.52E+06 4.15E+06 - - - 6.8832 1 230117_WJC_METTL3_WT_vs_EV_F05.21210.21210.2 7.28E-06 13/20 K.TITAYFGDLIR[166.11].R sp|Q96RS0|TGS1_HUMAN 1 1278.6848 1.62 44280 21210 2 1278.689385 640.3497 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 5.5 3884.1 - 747272 - - - 3.6186 - 2.305 0.526 - 492.5 1 2 0 0.0046 11 0 0 0 1.45E+07 8.96E+06 - - - 5.1837 1 230117_WJC_METTL3_WT_vs_EV_F05.21211.21211.2 5.59E-05 14/26 R.YAIQLITAASLVC[160.03]R.K sp|Q9Y230|RUVB2_HUMAN 1 1577.8599 1.85 44281 21211 2 1577.860919 789.9373 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 8.22 3884.3 - 707209 - - - 0.6148 - 2.75 0.532 - 593.9 1 2 0 0.001 14 0 0 0 3.49E+06 1.89E+06 - - - 5.5086 0.9735 230117_WJC_METTL3_WT_vs_EV_F05.21212.21212.2 3.65E-05 22-Nov S.ILTIEDGIFEVK.S "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1375.7599 26.81 44282 21212 2 1375.762691 688.8872 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3884.4 - 694418 - - - 2.0411 - 1.945 0.446 - 414.6 1 1 0 0.0028 12 0 0 0 5.14E+06 1.92E+05 - - - 4.0847 1 230117_WJC_METTL3_WT_vs_EV_F05.21223.21223.2 2.82E-13 19/34 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.84 44292 21223 2 1926.004509 964.0089 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3885.6 - 445712 - - - 0.6179 - 4.053 0.685 - 997.4 1 2 0 0.0012 18 0 0 0 3.85E+07 4.59E+07 - - - 7.5407 1 230117_WJC_METTL3_WT_vs_EV_F05.21230.21230.3 4.11E-11 26/68 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.79 44297 21230 3 1936.019424 646.3445 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3886.5 - 1.44E+07 - - - 4.047 - 3.111 0.634 - 704.6 1 2 0 0.0078 18 0 0 0 2.81E+07 3.54E+07 - - - 8.4324 1 230117_WJC_METTL3_WT_vs_EV_F05.21231.21231.2 6.48E-12 22/34 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.84 44298 21231 2 1936.015681 969.0131 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3886.6 - 2.01E+07 - - - 2.1136 - 4.166 0.653 - 1289.6 1 2 0 0.0041 18 0 0 0 3.85E+07 4.59E+07 - - - 7.371 1 230117_WJC_METTL3_WT_vs_EV_F05.21233.21233.2 0.000162 13/22 R.NFGASLLLPGLK[136.11].Q "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN,tr|D6RJC7|D6RJC7_HUMAN" 4 1236.7322 1.41 44300 21233 2 1236.734948 619.3734 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 8.75 3886.8 - 8.32E+06 - - - 2.2551 - 2.01 0.547 - 528.9 1 2 0 0.0028 12 0 0 0 3.71E+07 2.64E+07 - - - 4.9172 1 230117_WJC_METTL3_WT_vs_EV_F05.21235.21235.2 1.65E-05 13/24 K.NVLIVEDIIDTGK.T sp|P00492|HPRT_HUMAN 1 1427.7872 1.97 44302 21235 2 1427.792062 714.9009 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.03 3886.9 - 4.43E+06 - - - 3.4326 - 2.62 0.548 - 533.3 1 2 0 0.0049 13 0 0 0 1.02E+07 5.16E+06 - - - 5.559 1 230117_WJC_METTL3_WT_vs_EV_F05.21236.21236.2 7.44E-10 16/32 R.LWVGGLGPNTSLAALAR.E sp|Q8NDT2|RB15B_HUMAN 1 1694.9468 -1 44303 21236 2 1694.947632 848.4807 Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3 9.75 3887.1 - 2.69E+06 - - - 0.4968 - 3.4 0.635 - 691 1 2 0 0.0008 17 0 0 0 0.00E+00 0.00E+00 - - - 6.7396 0.8522 230117_WJC_METTL3_WT_vs_EV_F05.21237.21237.3 6.57 Sep-48 R.LWSTYLR[166.11]PLLVVR[166.11].T "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN,tr|K7EQG1|K7EQG1_HUMAN" 3 1634.9775 1.15 44304 21237 3 1634.983411 545.9998 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 10.84 3887.2 - 2.06E+06 - - - 3.6013 - 1.583 0.048 - 83.2 1 2 0 0.0059 13 0 0 0 3.56E+06 3.09E+06 - - - 0.3189 0.9931 230117_WJC_METTL3_WT_vs_EV_F05.21238.21238.3 0.115 Oct-48 R.LWSTYLRPLLVVR.T "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN,tr|K7EQG1|K7EQG1_HUMAN" 3 1614.961 1.2 44305 21238 3 1614.96555 539.3276 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 10.84 3887.3 - 1.72E+06 - - - 2.8279 - 1.622 0.197 - 120.4 1 2 0 0.0046 13 0 0 0 3.70E+06 3.09E+06 - - - 2.0464 0.9949 230117_WJC_METTL3_WT_vs_EV_F05.21241.21241.2 0.00185 20-Sep K.VLAISDLVIYR.T "sp|Q9HBF4|ZFYV1_HUMAN,tr|G3V5N8|G3V5N8_HUMAN" 2 1260.7442 1.58 44308 21241 2 1260.751225 631.3794 Zinc finger FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZFYVE1 PE=1 SV=1 5.81 3887.7 - 1.53E+06 - - - 5.5927 - 1.941 0.33 - 200.9 1 2 0 0.0071 11 0 0 0 3.42E+06 2.17E+06 - - - 3.2703 1 230117_WJC_METTL3_WT_vs_EV_F05.21243.21243.2 6.49E-08 18-Dec R.VYNALVAFIR.A sp|Q9BW92|SYTM_HUMAN 1 1164.6655 -1 44310 21243 2 1164.667071 583.34 "Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1" 8.72 3888 - 937074 - - - 1.324 - 2.304 0.563 - 593.2 1 2 0 0.0015 10 0 0 0 0.00E+00 0.00E+00 - - - 5.5286 0.8932 230117_WJC_METTL3_WT_vs_EV_F05.21246.21246.2 0.397 24-Jun R.LVSYLPGFC[160.03]SLVK.R "sp|Q9H3L0|MMAD_HUMAN,tr|F8WEC0|F8WEC0_HUMAN" 2 1481.7952 -1 44313 21246 2 1481.804626 741.9049 Cobalamin trafficking protein CblD OS=Homo sapiens OX=9606 GN=MMADHC PE=1 SV=2 8.2 3888.4 - 614923 - - - 6.3457 - 1.267 0.167 - 55.7 2 2 0 0.0094 13 0 0 0 0.00E+00 0.00E+00 - - - 0.7444 1 230117_WJC_METTL3_WT_vs_EV_F05.21248.21248.2 1.03E-06 14/30 R.IGNVEISQVTIVGIIR[166.11].H "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 1720.0122 -1 44315 21248 2 1720.011188 861.0134 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 6 3888.6 - 530893 - - - -0.6116 - 2.855 0.592 - 600.9 1 2 0 -0.0011 16 0 0 0 0.00E+00 0.00E+00 - - - 5.9924 0.9377 230117_WJC_METTL3_WT_vs_EV_F05.21252.21252.2 0.0093 26-Jul K.PSILTYQYAEDLIR.R sp|Q9BXW7|HDHD5_HUMAN 1 1680.8723 -1 44318 21252 2 1680.873184 841.4434 Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Homo sapiens OX=9606 GN=HDHD5 PE=1 SV=1 4.37 3889.2 - 0 - - - 0.5337 - 1.395 0.389 - 111.8 1 1 0 0.0009 14 0 0 0 0.00E+00 0.00E+00 - - - 2.7493 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.21253.21253.3 0.000234 Nov-68 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.79 44319 21253 3 1926.006466 643.0084 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3889.2 - 2.36E+06 - - - 1.634 - 1.638 0.458 - 94 1 2 0 0.0031 18 0 0 0 2.81E+07 3.54E+07 - - - 4.8742 1 230117_WJC_METTL3_WT_vs_EV_F05.21255.21255.2 2.28E-07 13/26 K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.76 44321 21255 2 1651.933386 826.9731 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3889.3 - 2.15E+06 - - - 1.0527 - 2.503 0.606 - 497.6 1 2 0 0.0017 14 0 0 0 8.38E+07 1.10E+08 - - - 5.8188 1 230117_WJC_METTL3_WT_vs_EV_F05.21256.21256.2 1.16E-05 22-Oct R.LFQVEYAIEAIK.L sp|P28066|PSA5_HUMAN 1 1422.7759 2.25 44322 21256 2 1422.778576 712.3952 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 4.53 3889.4 - 1.79E+06 - - - 1.9033 - 1.969 0.518 - 320.6 1 2 0 0.0027 12 0 0 0 3.85E+07 1.71E+07 - - - 4.6488 1 230117_WJC_METTL3_WT_vs_EV_F05.21257.21257.2 9.49E-05 15/26 K.LYTLVTYVPVTTFK.N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1643.9174 0.76 44323 21257 2 1643.919513 822.966 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3889.4 - 1.62E+06 - - - 1.2568 - 2.597 0.593 - 744.2 1 2 0 0.0021 14 0 0 0 8.38E+07 1.10E+08 - - - 5.8152 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.21258.21258.2 0.262 16-Sep K.SLDIYSFIK.E "sp|Q9NR50|EI2BG_HUMAN,tr|H0Y580|H0Y580_HUMAN" 2 1084.5805 0.89 44324 21258 2 1084.581675 543.2975 Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens OX=9606 GN=EIF2B3 PE=1 SV=1 5.55 3889.5 - 868912 - - - 1.1184 - 1.824 0.314 - 228.7 1 2 0 0.0012 9 0 0 0 7.87E+06 8.82E+06 - - - 3.0986 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21259.21259.2 0.00167 20-Dec K.LLTQYILNLGK.Y sp|O00203|AP3B1_HUMAN 1 1274.7598 1.62 44325 21259 2 1274.761456 638.3872 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 8.59 3889.5 - 848574 - - - 1.2802 - 2.019 0.471 - 533.7 1 2 0 0.0016 11 0 0 0 9.22E+06 5.68E+06 - - - 4.42 1 230117_WJC_METTL3_WT_vs_EV_F05.21265.21265.2 6.18E-05 20-Dec R.FVASYLEYAFR.K sp|Q96GM8|TOE1_HUMAN 1 1364.6765 -1 44331 21265 2 1364.672339 683.3455 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 6 3890.2 - 236583 - - - -3.0403 - 2.282 0.511 - 456.3 1 2 0 -0.0041 11 0 0 0 0.00E+00 0.00E+00 - - - 5.0459 0.8682 230117_WJC_METTL3_WT_vs_EV_F05.21268.21268.2 0.0057 20-Jul R.PTPFFMDPIYR[166.11].V "sp|Q03112|MECOM_HUMAN,tr|H9KVD4|H9KVD4_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN" 4 1392.6776 2.23 44334 21268 2 1392.676378 697.3461 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 6.26 3890.5 - 202650 - - - -0.8516 - 1.395 0.369 - 141.1 1 1 0 -0.0012 11 0 0 0 2.51E+06 1.12E+06 - - - 2.6666 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21274.21274.3 0.000129 15/52 K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 -1 44339 21274 3 1651.935816 551.6512 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3891.2 - 1.51E+07 - - - 2.5237 - 2.589 0.426 - 238.9 1 2 0 0.0042 14 0 0 0 0.00E+00 0.00E+00 - - - 5.8164 0.9967 230117_WJC_METTL3_WT_vs_EV_F05.21277.21277.2 0.00858 18-Nov R.TLGWEALLAR.R sp|Q16512|PKN1_HUMAN 1 1128.6291 -1 44342 21277 2 1128.63483 565.3218 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.66 3891.5 - 3.63E+06 - - - 5.038 - 1.911 0.339 - 304.8 1 2 0 0.0057 10 0 0 0 0.00E+00 0.00E+00 - - - 3.3508 1 230117_WJC_METTL3_WT_vs_EV_F05.21278.21278.2 1.97E-05 20-Nov K.TLC[160.03]PLC[160.03]FSILK.G "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1350.704 -1 44343 21278 2 1350.70738 676.3593 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 7.74 3891.6 - 3.53E+06 - - - 2.5276 - 2.094 0.524 - 320.3 1 2 0 0.0034 11 0 0 0 0.00E+00 0.00E+00 - - - 4.9096 1 230117_WJC_METTL3_WT_vs_EV_F05.21280.21280.2 0.000192 20-Oct R.EALDVLGAVLK[136.11].A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1134.674 1.26 44345 21280 2 1134.676069 568.3443 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3891.9 - 2.67E+06 - - - 1.8455 - 2.152 0.478 - 267.6 1 2 0 0.0021 11 0 0 0 2.84E+07 2.25E+07 - - - 4.6441 0.9956 230117_WJC_METTL3_WT_vs_EV_F05.21281.21281.2 0.0995 20-Nov R.NLIIEAVTNLR[166.11].L "sp|Q12789|TF3C1_HUMAN,tr|H3BU37|H3BU37_HUMAN" 2 1264.7379 -1 44346 21281 2 1264.742068 633.3762 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 6 3892 - 2.59E+06 - - - 3.3303 - 1.997 0.129 - 512.2 2 2 0 0.0042 11 0 0 0 0.00E+00 0.00E+00 - - - 1.7291 1 230117_WJC_METTL3_WT_vs_EV_F05.21284.21284.2 4.06E-06 20-Nov K.TLC[160.03]PLC[160.03]FSILK[136.11].G "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1358.7182 -1 44349 21284 2 1358.717812 680.3664 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 7.74 3892.4 - 2.14E+06 - - - -0.2605 - 2.117 0.507 - 308.1 1 2 0 -0.0004 11 0 0 0 0.00E+00 0.00E+00 - - - 4.8145 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.21285.21285.3 0.125 Sep-44 R.LFQVEYAIEAIK.L sp|P28066|PSA5_HUMAN 1 1422.7759 -1 44350 21285 3 1422.780523 475.2659 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 4.53 3892.5 - 2.04E+06 - - - 3.2718 - 1.703 0.237 - 87.7 1 2 0 0.0047 12 0 0 0 0.00E+00 0.00E+00 - - - 2.6567 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.21286.21286.2 0.655 14-Aug K.QFLIDWVR.K "sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 2 1075.5815 0.62 44351 21286 2 1075.585673 538.798 ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2 5.84 3892.7 - 1.73E+06 - - - 3.9123 - 1.652 0.215 - 196.8 1 2 0 0.0042 8 0 0 0 2.82E+06 4.57E+06 - - - 2.1416 1 230117_WJC_METTL3_WT_vs_EV_F05.21287.21287.2 0.0382 14/28 R.TIAIIAEGIPEALTR.K sp|P53396|ACLY_HUMAN 1 1566.8981 -1 44352 21287 2 1566.903702 784.4563 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.53 3892.8 - 1.65E+06 - - - 3.5701 - 2.843 0.469 - 650.2 1 2 0 0.0056 15 0 0 0 0.00E+00 0.00E+00 - - - 5.0721 1 230117_WJC_METTL3_WT_vs_EV_F05.21288.21288.2 5.08E-06 20-Nov R.FVASYLEYAFR[166.11].K sp|Q96GM8|TOE1_HUMAN 1 1374.6848 -1 44353 21288 2 1374.688742 688.3497 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 6 3892.9 - 1.60E+06 - - - 2.8981 - 2.11 0.501 - 384.3 1 2 0 0.004 11 0 0 0 0.00E+00 0.00E+00 - - - 4.7601 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21295.21295.2 2.18E-05 20-Oct R.EALDVLGAVLK.A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1126.6598 1.27 44359 21295 2 1126.66021 564.3372 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3893.6 - 3.92E+06 - - - 0.3861 - 2.014 0.466 - 354.8 1 2 0 0.0004 11 0 0 0 2.86E+07 2.26E+07 - - - 4.3767 1 230117_WJC_METTL3_WT_vs_EV_F05.21297.21297.2 0.000183 18-Dec K.C[160.03]MQLTDFILK.F "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1267.6305 -1 44361 21297 2 1267.631184 634.8225 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.83 3893.8 - 1.92E+06 - - - 0.5664 - 2.327 0.527 - 477.1 1 2 0 0.0007 10 0 0 0 0.00E+00 0.00E+00 - - - 5.2907 1 230117_WJC_METTL3_WT_vs_EV_F05.21299.21299.2 6.85E-10 14/26 R.VIVSDVQESFIWVR[166.11].Y sp|Q15393|SF3B3_HUMAN 1 1685.9016 -1 44363 21299 2 1685.90332 843.9581 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3893.9 - 813297 - - - 1.0042 - 2.817 0.616 - 475.3 1 2 0 0.0017 14 0 0 0 0.00E+00 0.00E+00 - - - 6.1892 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.21301.21301.2 0.0432 14-Jul R.IPFAFWAR.Y "sp|Q96JG8|MAGD4_HUMAN,tr|A0A804HKI1|A0A804HKI1_HUMAN" 2 1006.5389 -1 44365 21301 2 1006.537203 504.2767 Melanoma-associated antigen D4 OS=Homo sapiens OX=9606 GN=MAGED4 PE=1 SV=3 9.75 3894.2 - 489760 - - - -1.6582 - 1.381 0.357 - 170.1 1 2 0 -0.0017 8 0 0 0 0.00E+00 0.00E+00 - - - 2.6509 1 230117_WJC_METTL3_WT_vs_EV_F05.21302.21302.2 6.95E-06 14/24 R.VLGATLLPDLIQK[136.11].V "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN,tr|H0YDG0|H0YDG0_HUMAN" 5 1387.853 -1 44366 21302 2 1387.856078 694.9338 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.81 3894.3 - 465703 - - - 2.2164 - 2.673 0.557 - 589.7 1 2 0 0.0031 13 0 0 0 0.00E+00 0.00E+00 - - - 5.6775 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21306.21306.2 0.000116 14-Sep K.NFAFLEFR[166.11].S "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1052.5319 1.57 44370 21306 2 1052.533884 527.2732 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3894.8 - 394921 - - - 1.8983 - 1.669 0.418 - 341.8 1 2 0 0.002 8 0 0 0 9.06E+06 5.76E+06 - - - 3.6726 1 230117_WJC_METTL3_WT_vs_EV_F05.21307.21307.2 4.53E-09 14/24 K.YVFLDPLAGAVTK[136.11].T "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|A8MWX3|WASH4_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 6 1400.7795 2.47 44371 21307 2 1400.77871 701.397 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 5.83 3894.9 - 344512 - - - -0.5661 - 2.525 0.604 - 551.9 1 2 0 -0.0008 13 0 0 0 6.39E+06 2.58E+06 - - - 5.8791 1 230117_WJC_METTL3_WT_vs_EV_F05.21310.21310.2 1.31E-05 22-Dec R.IAAQDYIIGVFR[166.11].K "sp|Q96RR1|PEO1_HUMAN,tr|A0A2R8Y4V4|A0A2R8Y4V4_HUMAN,tr|A0A2R8Y746|A0A2R8Y746_HUMAN" 3 1374.7535 0.9 44374 21310 2 1374.758712 688.384 Twinkle mtDNA helicase OS=Homo sapiens OX=9606 GN=TWNK PE=1 SV=1 5.84 3895.3 - 264698 - - - 3.7869 - 2.532 0.435 - 601.7 1 2 0 0.0052 12 0 0 0 4.40E+06 4.87E+06 - - - 4.6967 0.9899 230117_WJC_METTL3_WT_vs_EV_F05.21314.21314.2 0.0518 20-Jul R.WMMIPPYVDPR[166.11].L sp|P48634|PRC2A_HUMAN 1 1413.6813 -1 44377 21314 2 1413.684797 707.8479 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.84 3895.8 - 101040 - - - 2.4956 - 1.356 0.112 - 114.9 1 2 0 0.0035 11 0 0 0 0.00E+00 0.00E+00 - - - 0.691 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.21316.21316.2 0.0204 18-Dec K.LLEPVLLLGK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1093.7111 1.66 44379 21316 2 1093.7155 547.8628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3896 - 9.36E+06 - - - 4.0385 - 2.504 0.305 - 450.8 1 2 0 0.0044 10 0 0 0 5.03E+08 3.02E+08 - - - 3.8545 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.21317.21317.2 0.000896 13/18 K.LLEPVLLLGK[136.11].E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1101.7253 1.66 44380 21317 2 1101.729142 551.8699 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3896.1 - 6.63E+06 - - - 3.5027 - 2.398 0.325 - 544 1 2 0 0.0039 10 0 0 0 5.03E+08 3.02E+08 - - - 3.8816 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.21318.21318.2 0.000817 20-Dec K.IALLNVELELK.A sp|Q99832|TCPH_HUMAN 1 1253.7595 10.18 44381 21318 2 1253.763139 627.887 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.53 3896.1 - 4.46E+06 - - - 2.9112 - 2.56 0.367 - 534.7 1 2 0 0.0036 11 0 0 0 1.06E+07 1.04E+06 - - - 4.2935 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.21319.21319.2 0.000395 14-Sep K.NFAFLEFR.S "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1042.5236 1.57 44382 21319 2 1042.527403 522.2691 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3896.2 - 1.38E+06 - - - 3.6325 - 1.731 0.434 - 357.3 1 2 0 0.0038 8 0 0 0 9.06E+06 5.76E+06 - - - 3.9002 1 230117_WJC_METTL3_WT_vs_EV_F05.21323.21323.2 2.46E-07 16/24 R.LDPETLESLGLIK[136.11].Q "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 1434.8061 3.13 44386 21323 2 1434.809551 718.4103 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 4.14 3896.8 - 946978 - - - 2.3968 - 2.682 0.557 - 912.3 1 2 0 0.0034 13 0 0 0 1.41E+07 4.50E+06 - - - 5.686 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.21325.21325.2 0.000831 16-Oct R.DIDAFWLQR[166.11].Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1172.5854 1.63 44388 21325 2 1172.588328 587.3 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3897 - 750265 - - - 2.5158 - 1.99 0.362 - 364.2 1 2 0 0.0029 9 0 0 0 1.75E+07 1.08E+07 - - - 3.7046 1 230117_WJC_METTL3_WT_vs_EV_F05.21326.21326.2 3.17E-08 13/24 K.TVQTAVFLYSLYK.E "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 1531.8286 1.07 44389 21326 2 1531.833714 766.9216 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.17 3897.2 - 615745 - - - 3.3176 - 2.665 0.576 - 405.5 1 2 0 0.0051 13 0 0 0 2.57E+06 2.40E+06 - - - 5.8095 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21327.21327.2 1.47E-05 22-Oct R.LGAPGFAWEPFR.G "sp|Q9HCM7|FBSL_HUMAN,tr|A0A3B3IRR3|A0A3B3IRR3_HUMAN,tr|A0A7P0Z485|A0A7P0Z485_HUMAN" 3 1346.6772 -1 44390 21327 2 1346.678831 674.3459 Fibrosin-1-like protein OS=Homo sapiens OX=9606 GN=FBRSL1 PE=1 SV=4 6 3897.3 - 572046 - - - 1.2431 - 2.249 0.449 - 403.1 1 2 0 0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 4.4893 0.999 230117_WJC_METTL3_WT_vs_EV_F05.21329.21329.2 0.00777 14-Oct K.SFDLLILK[136.11].E "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 955.5834 1.23 44392 21329 2 955.586188 478.799 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 5.55 3897.6 - 338508 - - - 2.95 - 1.767 0.311 - 281 1 2 0 0.0028 8 0 0 0 2.66E+06 2.17E+06 - - - 3.0541 1 230117_WJC_METTL3_WT_vs_EV_F05.21330.21330.2 3.09E-08 24-Nov K.FDFPVSYLPGPVK.A "sp|Q9NXE4|NSMA3_HUMAN,tr|A0A7P0T8J0|A0A7P0T8J0_HUMAN,tr|A0A7P0Z453|A0A7P0Z453_HUMAN,tr|C9J647|C9J647_HUMAN,tr|A0A7P0TAZ0|A0A7P0TAZ0_HUMAN,tr|A0A7P0T9J6|A0A7P0T9J6_HUMAN,tr|A0A7P0TB24|A0A7P0TB24_HUMAN" 7 1464.7653 4.63 44393 21330 2 1464.767704 733.3899 Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3 5.83 3897.7 - 337748 - - - 1.6392 - 2.215 0.65 - 323.6 1 2 0 0.0024 13 0 0 0 2.28E+06 4.92E+05 - - - 5.8822 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.21335.21335.2 0.0577 18-Aug K.LLLNLVDC[160.03]IR.S "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1227.7009 -1 44397 21335 2 1227.699253 614.8577 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 5.83 3898.4 - 0 - - - -1.3652 - 1.815 0.235 - 144.9 1 2 0 -0.0017 10 0 0 0 0.00E+00 0.00E+00 - - - 2.44 1 230117_WJC_METTL3_WT_vs_EV_F05.21339.21339.2 9.57E-12 14/32 R.VLALSVETDYTFPLAEK[136.11].V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN" 5 1903.007 -1 44401 21339 2 1903.005455 952.5108 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 4.14 3898.8 - 485567 - - - -0.8098 - 3.918 0.649 - 402.6 1 2 0 -0.0015 17 0 0 0 0.00E+00 0.00E+00 - - - 7.1914 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21340.21340.2 6.49E-05 24-Nov K.LLLDTFEYQGLVK[136.11].H "sp|Q7Z7K6|CENPV_HUMAN,tr|A0A0M3HER2|A0A0M3HER2_HUMAN" 2 1545.8534 -1 44402 21340 2 1545.855509 773.934 Centromere protein V OS=Homo sapiens OX=9606 GN=CENPV PE=1 SV=1 4.37 3898.9 - 453087 - - - 1.3669 - 2.046 0.464 - 283.1 1 2 0 0.0021 13 0 0 0 0.00E+00 0.00E+00 - - - 4.3048 1 230117_WJC_METTL3_WT_vs_EV_F05.21341.21341.2 1.77E-09 15/32 R.VLALSVETDYTFPLAEK.V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN" 5 1894.9928 -1 44403 21341 2 1894.993151 948.5037 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 4.14 3899 - 410270 - - - 0.1873 - 3.229 0.639 - 511.3 1 2 0 0.0004 17 0 0 0 0.00E+00 0.00E+00 - - - 6.6424 1 230117_WJC_METTL3_WT_vs_EV_F05.21343.21343.2 0.000149 18-Dec K.QEVPIIIVFR[166.11].A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1222.7313 1.41 44405 21343 2 1222.734084 612.3729 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3899.2 - 330099 - - - 2.2654 - 2.244 0.569 - 592.2 1 2 0 0.0028 10 0 0 0 1.31E+07 9.30E+06 - - - 5.4989 1 230117_WJC_METTL3_WT_vs_EV_F05.21344.21344.2 7.48E-11 14/32 R.EIISEMGELGVLGPTIK.G "sp|Q92947|GCDH_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKT3|K7EKT3_HUMAN" 3 1784.9594 -1 44406 21344 2 1784.959998 893.487 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.25 3899.3 - 316080 - - - 0.3417 - 3.147 0.657 - 587.2 1 2 0 0.0006 17 0 0 0 0.00E+00 0.00E+00 - - - 6.712 1 230117_WJC_METTL3_WT_vs_EV_F05.21345.21345.2 0.000149 22-Nov R.EVAAGYLVPLLR.S sp|Q13395|TARB1_HUMAN 1 1299.7551 -1 44407 21345 2 1299.756743 650.8848 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6.1 3899.4 - 207133 - - - 1.2849 - 2.313 0.468 - 524.2 1 2 0 0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 4.7035 1 230117_WJC_METTL3_WT_vs_EV_F05.21346.21346.2 2.57E-10 Dec-32 R.EIISEMGELGVLGPTIK[136.11].G "sp|Q92947|GCDH_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKT3|K7EKT3_HUMAN" 3 1792.9736 -1 44408 21346 2 1792.9756 897.4941 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.25 3899.6 - 202603 - - - 1.1222 - 2.912 0.638 - 389.8 1 2 0 0.002 17 0 0 0 0.00E+00 0.00E+00 - - - 6.3804 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21347.21347.2 0.000327 18-Oct K.LFEISDIVIK[136.11].D sp|Q9NSD9|SYFB_HUMAN 1 1183.6944 -1 44409 21347 2 1183.695238 592.8545 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 4.37 3899.7 - 170602 - - - 0.7282 - 1.986 0.458 - 236 1 2 0 0.0009 10 0 0 0 0.00E+00 0.00E+00 - - - 4.3387 0.999 230117_WJC_METTL3_WT_vs_EV_F05.21356.21356.2 0.000328 24-Sep K.ALEVAEYLTPVLK.E "sp|Q9NT62|ATG3_HUMAN,tr|F8WDI0|F8WDI0_HUMAN" 2 1444.8177 3.17 44417 21356 2 1444.816399 723.4161 Ubiquitin-like-conjugating enzyme ATG3 OS=Homo sapiens OX=9606 GN=ATG3 PE=1 SV=1 4.53 3900.7 - 209036 - - - -0.9233 - 1.926 0.397 - 293.3 1 2 0 -0.0013 13 0 0 0 1.06E+06 3.34E+05 - - - 3.655 0.8727 230117_WJC_METTL3_WT_vs_EV_F05.21358.21358.2 0.127 14-Jun N.GVSQLIQR[166.11].E sp|P48201|AT5G3_HUMAN 1 909.5271 0.93 44419 21358 2 909.527334 455.7708 "ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1" 9.75 3900.9 - 6.19E+06 - - - 0.2188 - 1.375 0.278 - 189.9 1 1 0 0.0002 8 0 0 0 1.00E+08 1.08E+08 - - - 2.0547 0.9165 230117_WJC_METTL3_WT_vs_EV_F05.21359.21359.2 0.783 14-Jul N.GVSQLIQR.E sp|P48201|AT5G3_HUMAN 1 899.5189 0.93 44420 21359 2 899.518924 450.7667 "ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1" 9.75 3901 - 4.78E+06 - - - 0.0656 - 1.685 0.272 - 213.3 1 1 0 0.0001 8 0 0 0 1.00E+08 1.08E+08 - - - 2.6236 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21362.21362.2 0.0561 16-Sep R.IPILFFANK.M "sp|Q9H0F7|ARL6_HUMAN,tr|A0A0J9YXT0|A0A0J9YXT0_HUMAN,tr|H7C5H6|H7C5H6_HUMAN" 3 1061.6274 2.25 44423 21362 2 1061.627878 531.821 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3901.1 - 873580 - - - 0.4945 - 2.105 0.364 - 297.1 1 2 0 0.0005 9 0 0 0 2.63E+06 1.17E+06 - - - 3.8827 1 230117_WJC_METTL3_WT_vs_EV_F05.21368.21368.2 0.000129 18-Nov K.QEVPIIIVFR.A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1212.723 1.41 44427 21368 2 1212.723722 607.3688 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3901.8 - 4.66E+06 - - - 0.5591 - 2.255 0.545 - 445.9 1 2 0 0.0007 10 0 0 0 1.31E+07 9.30E+06 - - - 5.3359 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.21369.21369.2 0.0136 18-Nov K.LFEISDIVIK.D sp|Q9NSD9|SYFB_HUMAN 1 1175.6802 5.3 44428 21369 2 1175.6794 588.8474 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 4.37 3901.9 - 1.49E+06 - - - -0.66 - 2.119 0.459 - 371.2 1 2 0 -0.0008 10 0 0 0 5.39E+06 1.02E+06 - - - 4.527 1 230117_WJC_METTL3_WT_vs_EV_F05.21372.21372.2 2.88E-07 24-Dec K.VSASPLLYTLIEK[136.11].T "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1440.8319 2.8 44431 21372 2 1440.836024 721.4232 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 5.97 3902.3 - 1.03E+06 - - - 2.8393 - 2.555 0.523 - 443.5 1 2 0 0.0041 13 0 0 0 1.01E+07 3.60E+06 - - - 5.3101 1 230117_WJC_METTL3_WT_vs_EV_F05.21377.21377.2 5.32E-07 24-Dec K.VFSATLGLVDIVK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1368.8108 1.09 44436 21377 2 1368.812789 685.4127 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3903 - 486182 - - - 1.4509 - 2.497 0.536 - 390.2 1 2 0 0.002 13 0 0 0 9.74E+07 8.93E+07 - - - 5.3479 1 230117_WJC_METTL3_WT_vs_EV_F05.21379.21379.2 1.01E-06 13/24 K.VFSATLGLVDIVK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1360.7966 1.09 44438 21379 2 1360.801264 681.4056 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3903.2 - 469722 - - - 3.4252 - 2.505 0.557 - 475.8 1 2 0 0.0047 13 0 0 0 9.74E+07 8.93E+07 - - - 5.5104 1 230117_WJC_METTL3_WT_vs_EV_F05.21387.21387.2 4.56E-05 22-Oct R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 -1 44445 21387 2 1603.764244 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3904.3 - 4.87E+06 - - - 0.1896 - 1.961 0.532 - 306.5 1 2 0 0.0003 12 0 0 0 0.00E+00 0.00E+00 - - - 4.7422 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.21394.21394.2 0.239 16-Jul R.LLPDFLLER[166.11].R "sp|Q12894|IFRD2_HUMAN,tr|H7C444|H7C444_HUMAN,tr|A0A0R4J2F6|A0A0R4J2F6_HUMAN" 3 1124.6469 0.04 44452 21394 2 1124.649972 563.3307 Interferon-related developmental regulator 2 OS=Homo sapiens OX=9606 GN=IFRD2 PE=1 SV=3 4.37 3905.1 - 561893 - - - 2.7173 - 1.816 0.204 - 103.8 1 2 0 0.0031 9 0 0 0 2.24E+05 6.05E+06 - - - 2.2729 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21395.21395.2 1.78E-05 24-Dec K.LEVAPISDIIAIK.S "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 6 1380.8228 2.87 44453 21395 2 1380.825989 691.4187 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 4.37 3905.3 - 488770 - - - 2.2965 - 2.137 0.469 - 336.4 1 2 0 0.0032 13 0 0 0 3.54E+07 1.23E+07 - - - 4.4531 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21397.21397.2 0.00685 13/24 K.LDNLLLDTEGFVK.L sp|Q16513|PKN2_HUMAN 1 1475.7872 1.77 44455 21397 2 1475.791297 738.9009 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.03 3905.5 - 343155 - - - 2.8026 - 2.11 0.33 - 305.9 1 2 0 0.0041 13 0 0 0 1.65E+06 9.30E+05 - - - 3.3935 1 230117_WJC_METTL3_WT_vs_EV_F05.21400.21400.2 2.63E-06 14/26 K.EIGLLADEIEIYGK.S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1561.8239 2.15 44458 21400 2 1561.83659 781.9192 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4 3905.9 - 320932 - - - 8.0995 - 2.624 0.498 - 558.9 1 2 0 0.0126 14 0 0 0 3.57E+06 1.66E+06 - - - 5.1361 1 230117_WJC_METTL3_WT_vs_EV_F05.21401.21401.2 1.83E-09 14/26 K.FGGDFLVYPGDPLR.F "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN" 4 1551.7722 47.09 44459 21401 2 1551.77377 776.8934 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.21 3906.1 - 320788 - - - 1.0253 - 3.167 0.675 - 583 1 2 0 0.0016 14 0 0 0 1.19E+07 2.54E+05 - - - 6.9189 1 230117_WJC_METTL3_WT_vs_EV_F05.21404.21404.2 6.49E-05 22-Dec K.IILDLISESPIK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1347.8105 1.16 44462 21404 2 1347.811593 674.9125 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3906.4 - 271711 - - - 0.8339 - 2.548 0.504 - 415.2 1 2 0 0.0011 12 0 0 0 1.95E+08 1.69E+08 - - - 5.2241 0.9961 230117_WJC_METTL3_WT_vs_EV_F05.21405.21405.2 0.0325 16-Oct K.VDILEMLQK.A "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1087.5947 1.33 44463 21405 2 1087.60124 544.8046 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.37 3906.6 - 267264 - - - 5.9838 - 2.249 0.383 - 269.9 1 2 0 0.0065 9 0 0 0 1.33E+06 1.00E+06 - - - 4.2126 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.21406.21406.3 0.00107 Sep-48 R.LLGNTFVALSDLR.C "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1417.7929 7.12 44464 21406 3 1417.797671 473.6049 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.84 3906.7 - 239750 - - - 3.3545 - 1.82 0.347 - 118.3 1 2 0 0.0048 13 0 0 0 1.91E+06 2.68E+05 - - - 4.031 0.9965 230117_WJC_METTL3_WT_vs_EV_F05.21409.21409.2 0.0784 16-Jun R.LDLLPFYAR[166.11].L sp|Q9HAU5|RENT2_HUMAN 1 1116.6207 1.6 44466 21409 2 1116.620893 559.3176 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 5.84 3907 - 267859 - - - 0.1719 - 1.443 0.189 - 82.2 1 2 0 0.0002 9 0 0 0 2.19E+06 1.37E+06 - - - 1.4978 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21412.21412.2 0.000142 16-Aug R.FWYFVSQLK[136.11].K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1224.6423 0.71 44469 21412 2 1224.644626 613.3284 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3907.1 - 2.08E+06 - - - 1.9148 - 1.561 0.486 - 241.3 1 2 0 0.0023 9 0 0 0 3.64E+07 5.15E+07 - - - 3.9182 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21413.21413.2 0.000267 16-Aug R.FWYFVSQLK.K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1216.6281 0.71 44470 21413 2 1216.630646 609.3213 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3907.2 - 1.29E+06 - - - 2.1083 - 1.674 0.509 - 239.3 1 2 0 0.0026 9 0 0 0 3.64E+07 5.15E+07 - - - 4.2902 1 230117_WJC_METTL3_WT_vs_EV_F05.21415.21415.2 0.000772 13/22 K.IILDLISESPIK.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1339.7963 1.16 44472 21415 2 1339.797389 670.9054 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3907.3 - 1.04E+06 - - - 0.8359 - 2.603 0.523 - 534.5 1 2 0 0.0011 12 0 0 0 1.95E+08 1.69E+08 - - - 5.4207 0.8974 230117_WJC_METTL3_WT_vs_EV_F05.21416.21416.2 0.712 12-Aug N.LNTLIQR[166.11].S "sp|P20036|DPA1_HUMAN,sp|Q00839|HNRPU_HUMAN,sp|Q8IUG5|MY18B_HUMAN,tr|A0A140T914|A0A140T914_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|F5H6I8|F5H6I8_HUMAN,tr|A0A140T9R4|A0A140T9R4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A140T9D6|A0A140T9D6_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A140T9Y9|A0A140T9Y9_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A140T9H1|A0A140T9H1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A140T9U4|A0A140T9U4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A140T9F8|A0A140T9F8_HUMAN,tr|J3KQ99|J3KQ99_HUMAN" 24 866.5213 0.79 44473 21416 2 866.522463 434.2679 "HLA class II histocompatibility antigen, DP alpha 1 chain OS=Homo sapiens OX=9606 GN=HLA-DPA1 PE=1 SV=1" 9.75 3907.5 - 568410 - - - 1.3179 - 1.877 0.133 - 257.7 1 1 0 0.0011 7 0 0 0 2.19E+06 2.79E+06 - - - 2.0181 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21417.21417.2 0.00062 14-Aug R.FDMIFIVK.D "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1011.5463 1.44 44474 21417 2 1011.547121 506.7804 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 5.84 3907.6 - 339816 - - - 0.7869 - 1.759 0.409 - 145.5 1 2 0 0.0008 8 0 0 0 2.48E+06 1.73E+06 - - - 3.7649 0.993 230117_WJC_METTL3_WT_vs_EV_F05.21418.21418.2 0.0874 20-Aug K.NFGLIASYLER.K "sp|O75376|NCOR1_HUMAN,tr|E7EVU5|E7EVU5_HUMAN,tr|J3KS51|J3KS51_HUMAN,tr|E7EW50|E7EW50_HUMAN,tr|A0A088AWL3|A0A088AWL3_HUMAN" 5 1281.6717 1.64 44475 21418 2 1281.678569 641.8431 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 6 3907.6 - 333509 - - - 5.3305 - 1.792 0.273 - 209.8 1 2 0 0.0068 11 0 0 0 3.35E+06 2.04E+06 - - - 2.6333 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21419.21419.2 0.00184 18-Aug K.VVLPTFILER[166.11].R sp|Q96SU4|OSBL9_HUMAN 1 1195.7204 1.74 44476 21419 2 1195.723331 598.8675 Oxysterol-binding protein-related protein 9 OS=Homo sapiens OX=9606 GN=OSBPL9 PE=1 SV=2 5.97 3907.7 - 288036 - - - 2.4387 - 1.577 0.394 - 213.4 1 2 0 0.0029 10 0 0 0 5.27E+06 3.03E+06 - - - 3.2217 0.9959 230117_WJC_METTL3_WT_vs_EV_F05.21420.21420.2 0.00187 14-Aug R.NDFLELLR[166.11].R sp|O60870|KIN17_HUMAN 1 1028.553 4.5 44477 21420 2 1028.558531 515.2838 DNA\RNA-binding protein KIN17 OS=Homo sapiens OX=9606 GN=KIN PE=1 SV=2 4.37 3907.9 - 271192 - - - 5.3629 - 1.742 0.357 - 240.7 1 2 0 0.0055 8 0 0 0 1.01E+07 2.24E+06 - - - 3.35 0.9953 230117_WJC_METTL3_WT_vs_EV_F05.21421.21421.2 0.285 16-May R.LLPDFLLER.R "sp|Q12894|IFRD2_HUMAN,tr|H7C444|H7C444_HUMAN,tr|A0A0R4J2F6|A0A0R4J2F6_HUMAN" 3 1114.6386 0.34 44478 21421 2 1114.639116 558.3266 Interferon-related developmental regulator 2 OS=Homo sapiens OX=9606 GN=IFRD2 PE=1 SV=3 4.37 3908 - 267859 - - - 0.4217 - 1.253 0.217 - 51.7 2 2 0 0.0005 9 0 0 0 2.66E+06 7.75E+06 - - - 1.1616 1 230117_WJC_METTL3_WT_vs_EV_F05.21425.21425.2 2.42E-08 28-Dec K.IVFVPGC[160.03]SIPLTIVK.S sp|P54136|SYRC_HUMAN 1 1641.9528 1.48 44480 21425 2 1641.95386 821.9837 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3908.5 - 8.28E+06 - - - 0.6535 - 2.274 0.637 - 258.7 1 2 0 0.0011 15 0 0 0 2.51E+07 1.70E+07 - - - 5.7653 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21426.21426.2 1.03E-06 28-Nov K.IVFVPGC[160.03]SIPLTIVK[136.11].S sp|P54136|SYRC_HUMAN 1 1649.967 1.48 44481 21426 2 1649.96743 825.9908 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3908.6 - 5.33E+06 - - - 0.2685 - 2.196 0.481 - 220.7 1 2 0 0.0004 15 0 0 0 2.51E+07 1.70E+07 - - - 4.5275 1 230117_WJC_METTL3_WT_vs_EV_F05.21428.21428.2 0.0486 13/24 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.71 44483 21428 2 1438.781748 720.3983 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3908.7 - 4.89E+06 - - - -0.1863 - 3.025 0.445 - 642.1 1 2 0 -0.0003 13 0 0 0 5.72E+07 3.34E+07 - - - 5.1686 1 230117_WJC_METTL3_WT_vs_EV_F05.21429.21429.2 0.00362 13/24 R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 1.7 44484 21429 2 1448.791438 725.4024 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3908.8 - 4.33E+06 - - - 0.7951 - 3.113 0.495 - 698.4 1 2 0 0.0012 13 0 0 0 5.70E+07 3.34E+07 - - - 5.6112 1 230117_WJC_METTL3_WT_vs_EV_F05.21430.21430.2 0.00191 16-Oct R.IDLAVLLGK.T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 940.5957 2.18 44485 21430 2 940.595914 471.3051 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3908.9 - 2.68E+06 - - - 0.2084 - 2.258 0.466 - 250.8 1 2 0 0.0002 9 0 0 0 1.13E+08 5.18E+07 - - - 4.8391 1 230117_WJC_METTL3_WT_vs_EV_F05.21432.21432.2 1.81E-07 14/26 K.VLLLSSPGLEELYR[166.11].C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1597.8955 0.87 44487 21432 2 1597.896596 799.955 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3909.2 - 2.41E+06 - - - 0.699 - 2.75 0.471 - 496.3 1 2 0 0.0011 14 0 0 0 8.06E+06 9.27E+06 - - - 5.058 1 230117_WJC_METTL3_WT_vs_EV_F05.21434.21434.2 0.000349 16-Dec R.IDLAVLLGK[136.11].T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 948.6099 2.18 44489 21434 2 948.608158 475.3122 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3909.4 - 1.75E+06 - - - -1.8553 - 2.252 0.472 - 338.8 1 2 0 -0.0018 9 0 0 0 1.13E+08 5.18E+07 - - - 4.8753 0.995 230117_WJC_METTL3_WT_vs_EV_F05.21438.21438.2 0.0275 14-Aug K.ENLLDFIK[136.11].H "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 998.5528 1.97 44493 21438 2 998.550813 500.2837 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.37 3909.9 - 1.28E+06 - - - -1.9869 - 1.856 0.203 - 211.2 1 2 0 -0.002 8 0 0 0 3.06E+07 1.55E+07 - - - 2.4049 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21447.21447.2 1.34E-05 24-Nov R.FDNVLPVSLAFDK.C "sp|O95352|ATG7_HUMAN,tr|H7BZ92|H7BZ92_HUMAN,tr|H7C2R3|H7C2R3_HUMAN,tr|H7C2J8|H7C2J8_HUMAN" 4 1463.766 -1 44501 21447 2 1463.766959 732.8903 Ubiquitin-like modifier-activating enzyme ATG7 OS=Homo sapiens OX=9606 GN=ATG7 PE=1 SV=1 4.21 3910.9 - 323310 - - - 0.634 - 1.896 0.478 - 290.5 1 2 0 0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2131 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.21449.21449.2 1.33E-05 22-Nov R.YFPTQALNFAFK[136.11].D "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 1453.7485 1.15 44503 21449 2 1453.74669 727.8815 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.59 3911.1 - 3.03E+06 - - - -1.2705 - 2.049 0.442 - 394.1 1 2 0 -0.0018 12 0 0 0 1.03E+08 8.96E+07 - - - 4.1925 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21451.21451.3 0.000194 14/48 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.83 44505 21451 3 1438.781881 480.6013 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3911.4 - 1.36E+06 - - - -0.0938 - 2.774 0.408 - 307.7 1 2 0 -0.0001 13 0 0 0 2.37E+06 1.30E+06 - - - 5.8551 1 230117_WJC_METTL3_WT_vs_EV_F05.21452.21452.2 1.58E-06 18-Nov R.FNLMAIVSDR.K "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y636|H0Y636_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 7 1164.5961 3.79 44506 21452 2 1164.597143 583.3053 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3911.5 - 1.12E+06 - - - 0.8707 - 2.302 0.521 - 554.5 1 2 0 0.001 10 0 0 0 8.86E+06 2.34E+06 - - - 5.2161 1 230117_WJC_METTL3_WT_vs_EV_F05.21455.21455.2 1.16E-05 13/20 K.LPDVYGVFQFK[136.11].V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1319.7005 1.47 44509 21455 2 1319.70126 660.8575 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.83 3911.9 - 1.09E+06 - - - 0.5577 - 2.303 0.538 - 617.5 1 2 0 0.0007 11 0 0 0 8.71E+06 5.95E+06 - - - 5.2712 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21458.21458.3 0.000314 16/48 R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 -1 44512 21458 3 1448.791273 483.9374 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3912.3 - 895685 - - - 0.6813 - 2.463 0.429 - 343.6 1 2 0 0.001 13 0 0 0 0.00E+00 0.00E+00 - - - 5.7666 0.9865 230117_WJC_METTL3_WT_vs_EV_F05.21463.21463.2 0.126 14-Aug R.SVFLTFLR.M "sp|Q9H1I8|ASCC2_HUMAN,tr|B1AH59|B1AH59_HUMAN" 2 981.5648 -1 44517 21463 2 981.563386 491.7897 Activating signal cointegrator 1 complex subunit 2 OS=Homo sapiens OX=9606 GN=ASCC2 PE=1 SV=3 9.47 3912.9 - 369746 - - - -1.3927 - 1.621 0.09 - 195.8 1 2 0 -0.0014 8 0 0 0 0.00E+00 0.00E+00 - - - 1.1621 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.21473.21473.2 0.0418 20-Aug R.ASLPLVLYIDR[166.11].F "sp|Q9NQV6|PRD10_HUMAN,tr|E9PLV1|E9PLV1_HUMAN" 2 1268.7368 0.97 44526 21473 2 1268.73682 635.3757 PR domain zinc finger protein 10 OS=Homo sapiens OX=9606 GN=PRDM10 PE=1 SV=3 5.88 3914.1 - 165467 - - - 0.0205 - 1.618 0.175 - 213.7 1 2 0 0 11 0 0 0 1.05E+06 1.09E+06 - - - 1.6353 0.9339 230117_WJC_METTL3_WT_vs_EV_F05.21475.21475.2 3.72 20-Jul K.LASALDLPLLR[166.11].L "sp|Q12768|WASC5_HUMAN,tr|E7EQI7|E7EQI7_HUMAN" 2 1190.7262 -1 44528 21475 2 1190.726617 596.3704 WASH complex subunit 5 OS=Homo sapiens OX=9606 GN=WASHC5 PE=1 SV=1 5.84 3914.4 - 0 - - - 0.3259 - 0.999 0.044 - 76 1 2 0 0.0004 11 0 0 0 0.00E+00 0.00E+00 - - - -0.6368 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21487.21487.2 0.03 14-Sep R.ILEFFGLK[136.11].K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 973.5728 2.2 44539 21487 2 973.573199 487.7937 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3915.8 - 152787 - - - 0.4047 - 1.795 0.302 - 207.5 1 2 0 0.0004 8 0 0 0 1.03E+08 4.67E+07 - - - 3.0358 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21490.21490.2 0.00209 14-Sep R.ILEFFGLK.K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 965.5586 2.2 44540 21490 2 965.558321 483.7866 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3916.2 - 1.22E+07 - - - -0.2941 - 1.678 0.409 - 214.7 1 2 0 -0.0003 8 0 0 0 1.03E+08 4.67E+07 - - - 3.6229 1 230117_WJC_METTL3_WT_vs_EV_F05.21492.21492.2 9.21E-07 20-Nov K.AFVDFLSDEIK.E sp|Q07021|C1QBP_HUMAN 1 1282.6445 1.72 44542 21492 2 1282.642864 642.3295 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.03 3916.3 - 3.02E+06 - - - -1.2903 - 2.065 0.545 - 348.9 1 2 0 -0.0017 11 0 0 0 1.68E+07 9.81E+06 - - - 5.0275 1 230117_WJC_METTL3_WT_vs_EV_F05.21493.21493.2 3.17E-06 22-Dec R.LLFPAVDDNLLK.F "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1356.7653 1.74 44543 21493 2 1356.76492 679.3899 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 4.21 3916.5 - 2.42E+06 - - - -0.2823 - 2.208 0.506 - 466.4 1 2 0 -0.0004 12 0 0 0 1.42E+07 8.15E+06 - - - 4.8623 0.9976 230117_WJC_METTL3_WT_vs_EV_F05.21495.21495.2 6.06E-05 22-Oct R.LLFPAVDDNLLK[136.11].F "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1364.7795 1.74 44545 21495 2 1364.775716 683.397 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 4.21 3916.7 - 1.32E+06 - - - -2.7748 - 2.016 0.447 - 328.7 1 2 0 -0.0038 12 0 0 0 1.42E+07 8.15E+06 - - - 4.1861 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.21498.21498.2 0.0384 16-Sep K.EVNLVLLLK.N "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1039.6641 999 44548 21498 2 1039.664512 520.8393 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 6.1 3917.1 - 948713 - - - 0.3655 - 1.813 0.325 - 365.6 1 2 0 0.0004 9 0 0 0 6.36E+06 0.00E+00 - - - 3.1626 0.9879 230117_WJC_METTL3_WT_vs_EV_F05.21501.21501.2 0.623 22-May R.LNMGEIETLDDY.- "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1411.6177 - 44551 21501 2 1411.618136 706.8161 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 3.43 3917.5 - 838751 - - - 0.3004 - 1.079 0.189 - 73 2 2 0 0.0004 12 0 0 0 - - - - - 0.5024 1 230117_WJC_METTL3_WT_vs_EV_F05.21507.21507.2 1.43E-07 20-Dec K.AFVDFLSDEIK[136.11].E sp|Q07021|C1QBP_HUMAN 1 1290.6587 1.72 44556 21507 2 1290.657025 646.3366 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.03 3918.2 - 213952 - - - -1.3125 - 2.445 0.519 - 471.2 1 2 0 -0.0017 11 0 0 0 1.68E+07 9.81E+06 - - - 5.2924 0.9764 230117_WJC_METTL3_WT_vs_EV_F05.21508.21508.2 9.85E-05 24-Aug K.VALVTASTDGIGF.A "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN" 5 1249.6554 - 44557 21508 2 1249.657149 625.835 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 3.8 3918.3 - 889534 - - - 1.3852 - 1.717 0.495 - 168.1 1 1 0 0.0017 13 0 0 0 - - - - - 4.0839 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.21513.21513.2 0.00125 18-Oct R.IQFFAIEIAR.N sp|Q9BVG4|PBDC1_HUMAN 1 1206.6761 4.9 44560 21513 2 1206.674649 604.3453 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 6 3918.8 - 231842 - - - -1.1975 - 2.157 0.395 - 335.9 1 2 0 -0.0014 10 0 0 0 1.18E+07 2.41E+06 - - - 4.1037 0.9929 230117_WJC_METTL3_WT_vs_EV_F05.21520.21520.2 0.448 14-Jul R.SWLLPVIR[166.11].D sp|Q5JTH9|RRP12_HUMAN 1 992.6047 0.69 44565 21520 2 992.604593 497.3096 RRP12-like protein OS=Homo sapiens OX=9606 GN=RRP12 PE=1 SV=2 9.47 3919.7 - 621760 - - - -0.0645 - 1.422 0.125 - 234.9 1 2 0 -0.0001 8 0 0 0 4.85E+06 7.04E+06 - - - 1.026 1 230117_WJC_METTL3_WT_vs_EV_F05.21524.21524.2 4.86E-07 13/26 R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.15 44569 21524 2 1470.879156 736.4478 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3920.2 - 603795 - - - -1.2544 - 2.536 0.615 - 377.3 1 2 0 -0.0018 14 0 0 0 8.31E+07 7.24E+07 - - - 5.9181 0.999 230117_WJC_METTL3_WT_vs_EV_F05.21526.21526.2 1.88 13/24 R.LGPLLLDPSLAVR[166.11].E sp|Q7Z4Q2|HEAT3_HUMAN 1 1372.8318 1.48 44571 21526 2 1372.830691 687.4232 HEAT repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=HEATR3 PE=1 SV=2 5.84 3920.5 - 449069 - - - -0.7765 - 2.271 0.306 - 454.1 1 2 0 -0.0011 13 0 0 0 4.67E+06 3.15E+06 - - - 3.4059 0.9973 230117_WJC_METTL3_WT_vs_EV_F05.21533.21533.2 0.303 16-Aug R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 24.77 44578 21533 2 1006.568963 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3921.4 - 78213.4 - - - -0.9289 - 1.544 0.275 - 147.1 1 2 0 -0.0009 9 0 0 0 1.10E+06 4.44E+04 - - - 2.3285 1 230117_WJC_METTL3_WT_vs_EV_F05.21536.21536.2 3.66E-06 14/22 K.WLAPDGLIFPDR[166.11].A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1408.7379 0.77 44579 21536 2 1408.737968 705.3762 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3921.8 - 8.07E+06 - - - 0.0795 - 2.792 0.516 - 656.4 1 2 0 0.0001 12 0 0 0 3.85E+07 4.99E+07 - - - 5.5537 1 230117_WJC_METTL3_WT_vs_EV_F05.21537.21537.2 7.40E-07 17/26 R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.15 44580 21537 2 1478.894656 740.4549 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3921.9 - 9.83E+06 - - - -0.3685 - 3.008 0.562 - 697.8 1 2 0 -0.0005 14 0 0 0 8.31E+07 7.24E+07 - - - 5.9554 1 230117_WJC_METTL3_WT_vs_EV_F05.21538.21538.2 2.37E-05 14/22 K.WLAPDGLIFPDR.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1398.7296 0.77 44581 21538 2 1398.729016 700.3721 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3922 - 5.81E+06 - - - -0.4075 - 2.787 0.514 - 718.5 1 2 0 -0.0006 12 0 0 0 3.85E+07 4.99E+07 - - - 5.5341 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21540.21540.3 1.89E-05 15/52 R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.75 44583 21540 3 1478.899372 493.9723 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3922.3 - 1.41E+06 - - - 2.8203 - 2.332 0.502 - 311.5 1 2 0 0.0042 14 0 0 0 1.08E+07 6.18E+06 - - - 6.3859 1 230117_WJC_METTL3_WT_vs_EV_F05.21541.21541.2 1.37E-08 17/26 K.TALALAIAQELGSK.V "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1384.7926 1.85 44584 21541 2 1384.792869 693.4036 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 5.66 3922.4 - 1.24E+06 - - - 0.2087 - 3.434 0.595 - 1316.9 1 2 0 0.0003 14 0 0 0 3.48E+06 1.88E+06 - - - 6.5316 1 230117_WJC_METTL3_WT_vs_EV_F05.21542.21542.2 0.000257 14/28 R.ELALALQEALEPAVR.L sp|Q5RKV6|EXOS6_HUMAN 1 1621.9039 0.87 44585 21542 2 1621.901871 811.9592 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 4.25 3922.5 - 1.22E+06 - - - -1.2646 - 2.982 0.463 - 748 1 2 0 -0.0021 15 0 0 0 3.71E+06 4.27E+06 - - - 5.1463 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21545.21545.2 0.000914 22-Dec R.FSPIPFPPLSYK.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1391.7489 28.4 44588 21545 2 1391.74947 696.8817 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3922.9 - 1.09E+06 - - - 0.3916 - 1.928 0.422 - 331.8 1 2 0 0.0005 12 0 0 0 3.65E+06 1.29E+05 - - - 3.885 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21546.21546.2 0.0209 18-Nov R.SLGPVELLLR[166.11].G "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1105.6735 2.97 44589 21546 2 1105.675048 553.844 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.72 3923.1 - 1.04E+06 - - - 1.4317 - 2.057 0.43 - 331.6 1 2 0 0.0016 10 0 0 0 1.20E+07 4.06E+06 - - - 4.2297 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.21551.21551.3 0.0289 Sep-52 K.TALALAIAQELGSK.V "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1384.7926 -1 44594 21551 3 1384.794482 462.6048 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 5.66 3923.7 - 653356 - - - 1.3735 - 1.537 0.307 - 43.6 1 2 0 0.0019 14 0 0 0 0.00E+00 0.00E+00 - - - 3.1045 0.9318 230117_WJC_METTL3_WT_vs_EV_F05.21552.21552.2 0.947 26-Jun K.LFGIESSSGTILWK.Q sp|Q8N766|EMC1_HUMAN 1 1536.8188 1 44595 21552 2 1536.81676 769.4167 ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1 6 3923.8 - 643494 - - - -1.3242 - 1.064 0.103 - 68.9 1 2 0 -0.002 14 0 0 0 2.43E+06 2.42E+06 - - - -0.0432 0.9772 230117_WJC_METTL3_WT_vs_EV_F05.21553.21553.2 0.000235 13/20 Q.AFADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1170.7012 7.48 44596 21553 2 1170.703105 586.3579 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3924 - 642307 - - - 1.5879 - 2.006 0.444 - 430.2 1 1 0 0.0019 11 0 0 0 2.85E+06 3.81E+05 - - - 4.203 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.21554.21554.2 0.00358 18-Aug R.LLVPILLPEK[136.11].C "sp|O75352|MPU1_HUMAN,tr|J3KSI4|J3KSI4_HUMAN,tr|J3KTK8|J3KTK8_HUMAN,tr|I3L1D2|I3L1D2_HUMAN,tr|I3L295|I3L295_HUMAN,tr|J3KT75|J3KT75_HUMAN,tr|J3QRD5|J3QRD5_HUMAN,tr|J3QS48|J3QS48_HUMAN,tr|J3QW43|J3QW43_HUMAN,tr|I3L261|I3L261_HUMAN,tr|I3L4E0|I3L4E0_HUMAN,tr|J3QQZ4|J3QQZ4_HUMAN,tr|I3L405|I3L405_HUMAN,tr|I3L4T1|I3L4T1_HUMAN" 14 1141.7566 1.15 44597 21554 2 1141.756653 571.8856 Mannose-P-dolichol utilization defect 1 protein OS=Homo sapiens OX=9606 GN=MPDU1 PE=1 SV=2 6 3924.1 - 612485 - - - 0.0613 - 1.456 0.477 - 96.9 1 2 0 0.0001 10 0 0 0 1.86E+06 1.61E+06 - - - 3.6128 1 230117_WJC_METTL3_WT_vs_EV_F05.21555.21555.2 1.54E-08 20/30 K.LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1793.9075 0.86 44598 21555 2 1793.903257 897.961 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3924.2 - 601632 - - - -2.3652 - 3.258 0.592 - 1181.4 1 2 0 -0.0042 16 0 0 0 6.22E+06 7.20E+06 - - - 6.316 0.9878 230117_WJC_METTL3_WT_vs_EV_F05.21575.21575.2 0.14 26-Jul R.FGLEGC[160.03]EVLIPALK[136.11].T "sp|Q02218|ODO1_HUMAN,tr|E9PFG7|E9PFG7_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|A0A0D9SFS3|A0A0D9SFS3_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 5 1552.8415 -1 44617 21575 2 1552.837716 777.428 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 4.53 3926.7 - 65329.9 - - - -2.4059 - 1.11 0.337 - 93.5 1 2 0 -0.0037 14 0 0 0 0.00E+00 0.00E+00 - - - 1.7908 1 230117_WJC_METTL3_WT_vs_EV_F05.21580.21580.2 4.26E-11 17/30 K.LFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1783.8992 0.81 44621 21580 2 1783.89945 892.9569 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3927.3 - 2.37E+06 - - - 0.1233 - 3.325 0.593 - 890.2 1 2 0 0.0002 16 0 0 0 6.22E+06 7.66E+06 - - - 6.3747 1 230117_WJC_METTL3_WT_vs_EV_F05.21582.21582.3 2.92E-07 19/52 R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.75 44623 21582 3 1470.877015 491.3009 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3927.5 - 1.70E+06 - - - -2.7099 - 3.116 0.544 - 432.2 1 2 0 -0.004 14 0 0 0 1.08E+07 6.18E+06 - - - 7.6244 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.21583.21583.2 0.00413 13/18 R.VVTDLISLIR[166.11].Q sp|P38432|COIL_HUMAN 1 1137.6997 -1 44624 21583 2 1137.699429 569.8571 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3927.6 - 1.65E+06 - - - -0.2206 - 2.242 0.374 - 652.5 1 2 0 -0.0003 10 0 0 0 0.00E+00 0.00E+00 - - - 4.0569 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.21586.21586.2 0.00685 18-Dec R.VVTDLISLIR.Q sp|P38432|COIL_HUMAN 1 1127.6914 -1 44627 21586 2 1127.691427 564.853 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3928 - 1.33E+06 - - - 0.0151 - 2.126 0.381 - 504.7 1 2 0 0 10 0 0 0 0.00E+00 0.00E+00 - - - 3.9604 0.9943 230117_WJC_METTL3_WT_vs_EV_F05.21587.21587.2 0.646 16-Jun R.FYELLVTGR.Y "sp|Q9UPS6|SET1B_HUMAN,tr|A0A0A0MQV9|A0A0A0MQV9_HUMAN" 2 1096.5917 2.49 44628 21587 2 1096.592108 549.3031 Histone-lysine N-methyltransferase SETD1B OS=Homo sapiens OX=9606 GN=SETD1B PE=1 SV=3 6 3928.1 - 1.11E+06 - - - 0.3757 - 1.28 0.172 - 117.9 1 2 0 0.0004 9 0 0 0 4.37E+06 1.76E+06 - - - 1.0254 1 230117_WJC_METTL3_WT_vs_EV_F05.21588.21588.2 5.28E-08 26-Dec K.TYVLNPLAPEFIPR.A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1628.8926 -1 44629 21588 2 1628.895886 815.4536 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.66 3928.2 - 1.11E+06 - - - 1.9995 - 2.605 0.578 - 411.8 1 2 0 0.0033 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7117 0.9846 230117_WJC_METTL3_WT_vs_EV_F05.21590.21590.3 0.029 Nov-40 K.IRFLILPDMLK.N sp|P62318|SMD3_HUMAN 1 1357.8156 -1 44631 21590 3 1357.815423 453.6125 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 8.75 3928.5 - 707729 - - - -0.1038 - 2.183 0.382 - 229.4 1 2 1 -0.0001 11 0 0 0 0.00E+00 0.00E+00 - - - 5.0167 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21591.21591.2 0.000347 20-Nov R.LFEFAGYDVLR[166.11].L sp|P54136|SYRC_HUMAN 1 1338.6848 -1 44632 21591 2 1338.684574 670.3497 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3928.6 - 635254 - - - -0.1374 - 2.246 0.453 - 373.8 1 2 0 -0.0002 11 0 0 0 0.00E+00 0.00E+00 - - - 4.5757 0.9312 230117_WJC_METTL3_WT_vs_EV_F05.21592.21592.2 0.16 16-Sep N.VLIIGELLK.Q "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 996.6583 -1 44633 21592 2 996.657983 499.3364 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.97 3928.8 - 599070 - - - -0.3371 - 1.759 0.338 - 238.1 1 1 0 -0.0003 9 0 0 0 0.00E+00 0.00E+00 - - - 3.1712 1 230117_WJC_METTL3_WT_vs_EV_F05.21593.21593.2 2.84E-05 20-Dec K.LDTSQWPLLLK[136.11].N "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1320.7533 0.86 44634 21593 2 1320.754209 661.3839 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 5.84 3928.9 - 564660 - - - 0.6973 - 2.55 0.529 - 681 1 2 0 0.0009 11 0 0 0 5.35E+06 6.25E+06 - - - 5.4803 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21596.21596.2 0.00623 20-Dec K.LDTSQWPLLLK.N "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1312.7391 0.7 44637 21596 2 1312.741679 657.3768 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 5.84 3929.3 - 509693 - - - 1.9737 - 2.584 0.376 - 661 1 2 0 0.0026 11 0 0 0 5.13E+06 7.32E+06 - - - 4.3855 1 230117_WJC_METTL3_WT_vs_EV_F05.21599.21599.2 0.0025 18-Nov R.DAVLLLFANK.Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1102.6386 -1 44639 21599 2 1102.639051 552.3266 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3929.7 - 7.45E+06 - - - 0.3673 - 2.437 0.434 - 553 1 2 0 0.0004 10 0 0 0 0.00E+00 0.00E+00 - - - 4.7328 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.21600.21600.2 0.00469 18-Sep K.FLDVLELAEK.F "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1175.6438 1.64 44640 21600 2 1175.642074 588.8292 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.14 3929.9 - 919806 - - - -1.4605 - 2.013 0.417 - 174.4 1 2 0 -0.0017 10 0 0 0 3.41E+06 2.08E+06 - - - 4.0733 1 230117_WJC_METTL3_WT_vs_EV_F05.21601.21601.2 0.000954 20-Sep R.LFEFAGYDVLR.L sp|P54136|SYRC_HUMAN 1 1328.6765 -1 44641 21601 2 1328.677187 665.3455 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3929.9 - 6.76E+06 - - - 0.5261 - 2.149 0.504 - 277.6 1 2 0 0.0007 11 0 0 0 0.00E+00 0.00E+00 - - - 4.8328 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21602.21602.2 0.0195 18-Oct R.DAVLLLFANK[136.11].Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1110.6528 -1 44642 21602 2 1110.652669 556.3337 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3930 - 3.29E+06 - - - -0.1594 - 2.295 0.425 - 402.9 1 2 0 -0.0002 10 0 0 0 0.00E+00 0.00E+00 - - - 4.4988 1 230117_WJC_METTL3_WT_vs_EV_F05.21603.21603.2 9.65E-10 16/30 R.IIGATDSSGELMFLMK.W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1711.8525 -1 44643 21603 2 1711.850961 856.9335 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3930.1 - 2.48E+06 - - - -0.8873 - 3.406 0.661 - 547.7 1 2 0 -0.0015 16 0 0 0 0.00E+00 0.00E+00 - - - 6.9357 1 230117_WJC_METTL3_WT_vs_EV_F05.21604.21604.2 6.32E-09 16/30 R.IIGATDSSGELMFLMK[136.11].W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1719.8667 -1 44644 21604 2 1719.867044 860.9406 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3930.2 - 2.05E+06 - - - 0.2116 - 3.466 0.625 - 546 1 2 0 0.0004 16 0 0 0 0.00E+00 0.00E+00 - - - 6.7131 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.21606.21606.2 0.00428 16-Jul K.APWELLELR[166.11].V "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A6Q8PF15|A0A6Q8PF15_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN,tr|A0A6Q8PFC1|A0A6Q8PFC1_HUMAN" 6 1135.6265 0.79 44646 21606 2 1135.62685 568.8205 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.53 3930.5 - 1.81E+06 - - - 0.295 - 1.704 0.4 - 198.6 1 2 0 0.0003 9 0 0 0 3.79E+06 4.83E+06 - - - 3.5372 0.9985 230117_WJC_METTL3_WT_vs_EV_F05.21610.21610.2 0.0156 16-Oct R.LVTLEEFLK.A "sp|P80303|NUCB2_HUMAN,tr|H0YD18|H0YD18_HUMAN,tr|E9PKG6|E9PKG6_HUMAN" 3 1090.6274 -1 44650 21610 2 1090.630611 546.321 Nucleobindin-2 OS=Homo sapiens OX=9606 GN=NUCB2 PE=1 SV=3 4.53 3931 - 1.24E+06 - - - 2.9332 - 1.888 0.226 - 248.5 1 2 0 0.0032 9 0 0 0 0.00E+00 0.00E+00 - - - 2.5478 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21613.21613.2 0.00206 13/20 K.VTDLLGGLFSK[136.11].T "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1156.6583 -1 44653 21613 2 1156.65912 579.3364 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.81 3931.4 - 982647 - - - 0.6873 - 2.757 0.378 - 822 1 2 0 0.0008 11 0 0 0 0.00E+00 0.00E+00 - - - 4.5762 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21617.21617.2 2.71E-05 20-Oct R.FFPLESWQIGK.L "sp|P30046|DOPD_HUMAN,tr|J3KQ18|J3KQ18_HUMAN,tr|H7C342|H7C342_HUMAN" 3 1350.6972 0.62 44657 21617 2 1350.700588 676.3559 D-dopachrome decarboxylase OS=Homo sapiens OX=9606 GN=DDT PE=1 SV=3 6 3931.9 - 719988 - - - 2.4913 - 1.897 0.494 - 242.5 1 2 0 0.0034 11 0 0 0 1.48E+06 2.40E+06 - - - 4.4207 1 230117_WJC_METTL3_WT_vs_EV_F05.21621.21621.2 8.19E-06 13/20 R.VINQMLEFAFR[166.11].Y "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 1376.715 -1 44660 21621 2 1376.718211 689.3648 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 5.97 3932.4 - 519729 - - - 2.3236 - 2.388 0.462 - 725 1 2 0 0.0032 11 0 0 0 0.00E+00 0.00E+00 - - - 4.8071 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21622.21622.2 3.89E-06 20-Nov R.SVVTVIDVFYK.Y sp|Q5D862|FILA2_HUMAN 1 1268.7016 37.54 44661 21622 2 1268.70185 635.3581 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 5.55 3932.4 - 1.14E+07 - - - 0.1655 - 2.395 0.389 - 382.9 1 2 0 0.0002 11 0 0 0 4.53E+07 1.21E+06 - - - 4.2768 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21624.21624.2 0.00173 18-Nov R.DALLLIFANK.Q "sp|P36406|TRI23_HUMAN,sp|P62330|ARF6_HUMAN" 2 1116.6543 -1 44663 21624 2 1116.654192 559.3344 E3 ubiquitin-protein ligase TRIM23 OS=Homo sapiens OX=9606 GN=TRIM23 PE=1 SV=1 5.84 3932.6 - 2.22E+06 - - - -0.0931 - 2.443 0.401 - 404.4 1 2 0 -0.0001 10 0 0 0 0.00E+00 0.00E+00 - - - 4.496 1 230117_WJC_METTL3_WT_vs_EV_F05.21627.21627.2 3.14E-05 13/20 K.YPSPFFVFGEK[136.11].L sp|Q08211|DHX9_HUMAN 1 1324.6583 0.99 44666 21627 2 1324.65808 663.3364 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3932.8 - 1.62E+06 - - - -0.185 - 2.388 0.505 - 709.8 1 2 0 -0.0002 11 0 0 0 8.80E+07 8.93E+07 - - - 5.1256 1 230117_WJC_METTL3_WT_vs_EV_F05.21628.21628.2 2.55E-06 20-Nov K.YPSPFFVFGEK.L sp|Q08211|DHX9_HUMAN 1 1316.6441 0.99 44667 21628 2 1316.643955 659.3293 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3932.9 - 1.56E+06 - - - -0.1291 - 2.252 0.497 - 476.7 1 2 0 -0.0002 11 0 0 0 8.80E+07 8.92E+07 - - - 4.9079 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21631.21631.2 0.000585 14-Sep R.AAFLNFFR.D sp|Q5JTZ9|SYAM_HUMAN 1 984.5181 -1 44670 21631 2 984.517732 493.2663 "Alanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=AARS2 PE=1 SV=1" 9.79 3933.2 - 987944 - - - -0.4114 - 1.636 0.442 - 292.6 1 2 0 -0.0004 8 0 0 0 0.00E+00 0.00E+00 - - - 3.7901 1 230117_WJC_METTL3_WT_vs_EV_F05.21633.21633.2 1.25E-09 20/30 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 1.02 44672 21633 2 1807.923935 904.9689 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3933.4 - 876778 - - - 0.4342 - 3.39 0.6 - 1214.8 1 2 0 0.0008 16 0 0 0 3.96E+07 3.90E+07 - - - 6.4738 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.21634.21634.2 0.000424 20-Oct R.VINQMLEFAFR.Y "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 1366.7067 -1 44673 21634 2 1366.706164 684.3606 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 5.97 3933.5 - 875207 - - - -0.4229 - 1.916 0.46 - 292.1 1 2 0 -0.0006 11 0 0 0 0.00E+00 0.00E+00 - - - 4.1974 0.9938 230117_WJC_METTL3_WT_vs_EV_F05.21635.21635.2 0.271 18-Jul R.GLIPVFALGR[166.11].A "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1051.6418 -1 44674 21635 2 1051.641986 526.8282 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 9.75 3933.7 - 762289 - - - 0.2044 - 1.498 0.158 - 64.3 5 2 0 0.0002 10 0 0 0 0.00E+00 0.00E+00 - - - 1.0237 1 230117_WJC_METTL3_WT_vs_EV_F05.21637.21637.2 5.29E-09 13/22 R.FSTFFDDAPVFR.L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1447.6772 -1 44676 21637 2 1447.677222 724.8459 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3933.9 - 692008 - - - 0.0041 - 2.367 0.625 - 540.3 1 2 0 0 12 0 0 0 0.00E+00 0.00E+00 - - - 5.9243 1 230117_WJC_METTL3_WT_vs_EV_F05.21638.21638.2 3.07E-06 13/24 K.SVDPTLALSVYLR[166.11].A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1442.8009 -1 44677 21638 2 1442.799456 722.4077 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.55 3934.1 - 667996 - - - -0.9662 - 2.705 0.591 - 495.9 1 2 0 -0.0014 13 0 0 0 0.00E+00 0.00E+00 - - - 5.9596 1 230117_WJC_METTL3_WT_vs_EV_F05.21639.21639.2 1.28E-07 19/30 K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 -1 44678 21639 2 1797.915444 899.9647 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3934.2 - 648207 - - - 0.3137 - 3.581 0.628 - 1023.6 1 2 0 0.0006 16 0 0 0 0.00E+00 0.00E+00 - - - 6.8155 1 230117_WJC_METTL3_WT_vs_EV_F05.21644.21644.3 2.15E-07 14/60 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 -1 44682 21644 3 1807.923329 603.6483 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3934.7 - 5.14E+06 - - - 0.099 - 2.657 0.563 - 245.5 1 2 0 0.0002 16 0 0 0 0.00E+00 0.00E+00 - - - 7.3242 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21645.21645.3 0.0174 Sep-60 K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 -1 44683 21645 3 1797.914649 600.3122 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3934.8 - 4.47E+06 - - - -0.1285 - 2.051 0.367 - 94.2 1 2 0 -0.0002 16 0 0 0 0.00E+00 0.00E+00 - - - 4.4748 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.21646.21646.2 0.0121 14-Aug R.GFGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 921.5204 1.09 44684 21646 2 921.519811 461.7675 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3934.8 - 3.99E+06 - - - -0.612 - 1.438 0.491 - 179 1 2 0 -0.0006 8 0 0 0 4.17E+08 3.82E+08 - - - 3.7629 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21647.21647.2 9.26E-05 14-Aug R.GFGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 913.5062 1.09 44685 21647 2 913.505714 457.7604 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3934.9 - 3.05E+06 - - - -0.5046 - 1.507 0.474 - 205.1 1 2 0 -0.0005 8 0 0 0 4.17E+08 3.82E+08 - - - 3.7787 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.21650.21650.2 0.0109 20-Jul R.FLDELDAVQMD.- "sp|O15160|RPAC1_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 3 1294.5751 - 44688 21650 2 1294.573697 648.2948 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 3.59 3935.1 - 1.30E+06 - - - -1.0984 - 1.513 0.365 - 118.2 1 2 0 -0.0014 11 0 0 0 - - - - - 2.8567 1 230117_WJC_METTL3_WT_vs_EV_F05.21651.21651.2 8.29E-08 22-Nov R.FSTFFDDAPVFR[166.11].L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1457.6855 -1 44689 21651 2 1457.685642 729.85 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3935.1 - 1.30E+06 - - - 0.107 - 2.156 0.59 - 375.3 1 2 0 0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4201 1 230117_WJC_METTL3_WT_vs_EV_F05.21652.21652.2 3.52E-06 20-Dec K.FIWSEISYLSK.W sp|Q16706|MA2A1_HUMAN 1 1371.7075 -1 44690 21652 2 1371.708436 686.861 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 6 3935.3 - 1.04E+06 - - - 0.7159 - 2.285 0.555 - 439.1 1 2 0 0.001 11 0 0 0 0.00E+00 0.00E+00 - - - 5.3754 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21653.21653.2 9.09E-06 26-Aug R.ILLDIDNDTESTAL.- sp|Q68EM7|RHG17_HUMAN 1 1531.7617 - 44691 21653 2 1531.763983 766.8881 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 3.37 3935.4 - 873402 - - - 1.4682 - 1.966 0.491 - 169 1 2 0 0.0022 14 0 0 0 - - - - - 4.3632 1 230117_WJC_METTL3_WT_vs_EV_F05.21654.21654.2 8.14E-05 20/32 K.ILGSGISSSSVLHGMVF.K sp|P50990|TCPQ_HUMAN 1 1689.876 - 44692 21654 2 1689.878529 845.9453 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.74 3935.5 - 717616 - - - 1.5013 - 2.679 0.518 - 809.4 1 1 0 0.0025 17 0 0 0 - - - - - 5.2889 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21655.21655.2 0.031 18-Sep K.SLESFVELMK.T sp|Q6KB66|K2C80_HUMAN 1 1181.6002 -1 44693 21655 2 1181.602027 591.8074 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 4.53 3935.6 - 680844 - - - 1.5369 - 2.021 0.362 - 180.8 1 2 0 0.0018 10 0 0 0 0.00E+00 0.00E+00 - - - 3.6781 1 230117_WJC_METTL3_WT_vs_EV_F05.21657.21657.2 2.30E-07 17/24 K.TPFLLVGTQIDLR.D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1471.8399 -1 44695 21657 2 1471.838216 736.9272 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3935.9 - 668749 - - - -1.1204 - 3.306 0.612 - 1143.6 1 2 0 -0.0016 13 0 0 0 0.00E+00 0.00E+00 - - - 6.6296 1 230117_WJC_METTL3_WT_vs_EV_F05.21659.21659.2 2.37E-08 15/30 R.IMEGPAFNFLDAPAVR.V sp|P11177|ODPB_HUMAN 1 1746.8763 -1 44697 21659 2 1746.886411 874.4454 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 4.37 3936.1 - 559086 - - - 5.7726 - 2.952 0.588 - 751.9 1 2 0 0.0101 16 0 0 0 0.00E+00 0.00E+00 - - - 6.0421 0.9983 230117_WJC_METTL3_WT_vs_EV_F05.21660.21660.2 0.045 16-Sep K.LLELDSFLK.E "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|K9J957|K9J957_HUMAN,tr|B7Z8D3|B7Z8D3_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 5 1076.6118 1.36 44698 21660 2 1076.611153 539.3132 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.37 3936.3 - 552473 - - - -0.5657 - 1.722 0.269 - 163.2 1 2 0 -0.0006 9 0 0 0 8.16E+06 5.99E+06 - - - 2.6 0.9968 230117_WJC_METTL3_WT_vs_EV_F05.21662.21662.2 0.177 18-Sep R.DALLLIFANK[136.11].Q "sp|P36406|TRI23_HUMAN,sp|P62330|ARF6_HUMAN" 2 1124.6685 -1 44699 21662 2 1124.668984 563.3415 E3 ubiquitin-protein ligase TRIM23 OS=Homo sapiens OX=9606 GN=TRIM23 PE=1 SV=1 5.84 3936.5 - 398781 - - - 0.4339 - 1.351 0.215 - 137.4 1 2 0 0.0005 10 0 0 0 0.00E+00 0.00E+00 - - - 1.4686 1 230117_WJC_METTL3_WT_vs_EV_F05.21664.21664.2 0.00149 20-Dec R.IFGLLMGTLQK.F sp|Q9H307|PININ_HUMAN 1 1219.6999 1.19 44701 21664 2 1219.699954 610.8572 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3936.6 - 1.96E+07 - - - 0.0721 - 2.34 0.508 - 467.2 1 2 0 0.0001 11 0 0 0 4.83E+07 4.05E+07 - - - 5.0929 1 230117_WJC_METTL3_WT_vs_EV_F05.21665.21665.2 3.15E-05 20-Nov R.IFGLLMGTLQK[136.11].F sp|Q9H307|PININ_HUMAN 1 1227.7141 1.19 44702 21665 2 1227.714155 614.8643 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3936.6 - 1.91E+07 - - - 0.0725 - 2.332 0.498 - 338.1 1 2 0 0.0001 11 0 0 0 4.83E+07 4.05E+07 - - - 5.0098 1 230117_WJC_METTL3_WT_vs_EV_F05.21666.21666.3 2.43E-07 15/60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 50.15 44703 21666 3 1796.00537 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3936.6 - 1.80E+07 - - - 0.5601 - 3.129 0.546 - 407.8 1 2 0 0.001 16 0 0 0 4.30E+07 8.58E+05 - - - 7.554 1 230117_WJC_METTL3_WT_vs_EV_F05.21667.21667.2 0.000276 13/24 N.IVGLVGVDQFLVK.T sp|P13639|EF2_HUMAN 1 1385.8282 -1 44704 21667 2 1385.828149 693.9214 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3936.7 - 5.77E+06 - - - -0.0642 - 2.419 0.553 - 422.4 1 1 0 -0.0001 13 0 0 0 0.00E+00 0.00E+00 - - - 5.3926 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.21670.21670.2 0.000412 20-Sep R.ASILNTWISLK[136.11].Q "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN" 2 1252.7271 1.71 44707 21670 2 1252.731767 627.3708 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 8.8 3936.8 - 3.02E+06 - - - 3.747 - 1.805 0.371 - 256 1 2 0 0.0047 11 0 0 0 1.17E+07 6.85E+06 - - - 3.3773 1 230117_WJC_METTL3_WT_vs_EV_F05.21671.21671.2 0.00418 13/24 K.TPFLLVGTQIDLR[166.11].D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1481.8481 -1 44708 21671 2 1481.846885 741.9313 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3936.9 - 2.53E+06 - - - -0.8435 - 2.978 0.459 - 751.7 1 2 0 -0.0013 13 0 0 0 0.00E+00 0.00E+00 - - - 5.2315 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21672.21672.2 0.00717 16-Sep K.GVIDLIFEK.A "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 1032.5855 -1 44709 21672 2 1032.586107 517.3001 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 3937 - 2.23E+06 - - - 0.5414 - 1.7 0.331 - 176.8 1 2 0 0.0006 9 0 0 0 0.00E+00 0.00E+00 - - - 3.0207 1 230117_WJC_METTL3_WT_vs_EV_F05.21673.21673.3 3.52E-14 28/72 R.GPLLVQDVVFTDEMAHFDR.E sp|P04040|CATA_HUMAN 1 2188.0623 73.13 44710 21673 3 2188.062337 730.3614 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 4.22 3937 - 2.11E+06 - - - 0.0215 - 4.263 0.731 - 1095.7 1 2 0 0 19 0 0 0 1.73E+07 2.37E+05 - - - 10.2522 1 230117_WJC_METTL3_WT_vs_EV_F05.21674.21674.2 0.00031 12-Oct G.FGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 856.4847 -1 44711 21674 2 856.48411 429.2496 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3937.1 - 1.98E+06 - - - -0.7017 - 2.031 0.478 - 263.2 1 1 0 -0.0006 7 0 0 0 0.00E+00 0.00E+00 - - - 4.8163 1 230117_WJC_METTL3_WT_vs_EV_F05.21675.21675.2 0.000799 24-Nov N.IVGLVGVDQFLVK[136.11].T sp|P13639|EF2_HUMAN 1 1393.8424 -1 44712 21675 2 1393.844484 697.9285 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3937.2 - 1.93E+06 - - - 1.4679 - 2.38 0.475 - 333.5 1 1 0 0.002 13 0 0 0 0.00E+00 0.00E+00 - - - 4.7741 1 230117_WJC_METTL3_WT_vs_EV_F05.21676.21676.2 0.000261 18-Dec K.IATLISSFLK.E "sp|O95394|AGM1_HUMAN,tr|A0A494C1E2|A0A494C1E2_HUMAN,tr|J3KN95|J3KN95_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C1Q4|A0A494C1Q4_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|A0A087WT27|A0A087WT27_HUMAN" 7 1091.659 -1 44713 21676 2 1091.658299 546.8368 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 8.75 3937.3 - 1.93E+06 - - - -0.6852 - 2.487 0.427 - 367.4 1 2 0 -0.0007 10 0 0 0 0.00E+00 0.00E+00 - - - 4.7377 0.9802 230117_WJC_METTL3_WT_vs_EV_F05.21677.21677.2 0.00225 12-Aug G.FGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 864.4989 -1 44714 21677 2 864.500129 433.2567 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3937.4 - 1.65E+06 - - - 1.4089 - 1.695 0.521 - 156.6 1 1 0 0.0012 7 0 0 0 0.00E+00 0.00E+00 - - - 4.5607 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.21678.21678.2 0.00356 18-Oct K.FLLLQGLVEK[136.11].E "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 1166.7154 -1 44715 21678 2 1166.714281 584.365 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 6 3937.4 - 1.53E+06 - - - -0.9985 - 2.036 0.378 - 291.2 1 2 0 -0.0012 10 0 0 0 0.00E+00 0.00E+00 - - - 3.8171 0.8994 230117_WJC_METTL3_WT_vs_EV_F05.21681.21681.2 0.0132 30-Jul L.SLGIETAGGVMTVLIK.R "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 1587.8906 -1 44718 21681 2 1587.892069 794.9526 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.72 3937.8 - 1.20E+06 - - - 0.9377 - 1.598 0.255 - 96.5 1 1 0 0.0015 16 0 0 0 0.00E+00 0.00E+00 - - - 2.0764 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21685.21685.2 0.00114 18-Oct K.FLLLQGLVEK.E "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 1158.7012 -1 44721 21685 2 1158.701258 580.3579 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 6 3938.2 - 4.34E+06 - - - 0.0104 - 2.165 0.451 - 307.6 1 2 0 0 10 0 0 0 0.00E+00 0.00E+00 - - - 4.5281 1 230117_WJC_METTL3_WT_vs_EV_F05.21687.21687.2 5.19E-05 14/30 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 -1 44723 21687 2 1796.003064 899.0095 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3938.3 - 3.39E+06 - - - -0.7238 - 3.419 0.599 - 696.1 1 2 0 -0.0013 16 0 0 0 0.00E+00 0.00E+00 - - - 6.4872 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21688.21688.3 8.48E-06 14/44 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 95.78 44724 21688 3 1459.792299 487.6047 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3938.4 - 2.22E+06 - - - 0.0363 - 2.85 0.42 - 393.5 1 2 0 0.0001 12 0 0 0 6.85E+07 7.15E+05 - - - 6.1256 0.9879 230117_WJC_METTL3_WT_vs_EV_F05.21690.21690.2 0.117 12-Jun K.ELFSFFR.D "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 944.4756 2.08 44726 21690 2 944.474398 473.2451 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6.1 3938.5 - 1.77E+06 - - - -1.2758 - 1.309 0.176 - 154.8 1 2 0 -0.0012 7 0 0 0 4.20E+06 2.02E+06 - - - 1.1937 1 230117_WJC_METTL3_WT_vs_EV_F05.21691.21691.2 3.29E-06 14/22 K.ITVNEVELLVMK[136.11].A "sp|Q9UNM6|PSD13_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 2 1394.7934 -1 44727 21691 2 1394.794181 698.404 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 4.53 3938.6 - 1.56E+06 - - - 0.532 - 2.993 0.45 - 725 1 2 0 0.0007 12 0 0 0 0.00E+00 0.00E+00 - - - 5.249 0.97 230117_WJC_METTL3_WT_vs_EV_F05.21692.21692.2 0.0533 20-Nov K.AIVEFLSNLAR.H sp|Q13112|CAF1B_HUMAN 1 1231.6925 1.76 44728 21692 2 1231.685288 616.8535 Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1 6.05 3938.6 - 3.01E+06 - - - -5.8326 - 2.167 0.267 - 457.3 1 2 0 -0.0072 11 0 0 0 9.11E+06 5.17E+06 - - - 3.1029 0.9772 230117_WJC_METTL3_WT_vs_EV_F05.21695.21695.2 3.15 12-Jun K.ELFSFFR[166.11].D "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 954.4839 -1 44731 21695 2 954.484664 478.2492 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6.1 3939 - 930663 - - - 0.8287 - 1.109 0.079 - 155.1 1 2 0 0.0008 7 0 0 0 0.00E+00 0.00E+00 - - - -0.0479 0.995 230117_WJC_METTL3_WT_vs_EV_F05.21697.21697.2 0.449 16-Sep K.LAASLWLWK.S "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1086.6226 10.73 44733 21697 2 1086.625683 544.3186 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.75 3939.2 - 810080 - - - 2.8354 - 1.46 0.167 - 122.8 1 2 0 0.0031 9 0 0 0 1.19E+07 1.11E+06 - - - 1.3683 0.9408 230117_WJC_METTL3_WT_vs_EV_F05.21698.21698.2 0.000512 22-Aug R.FVVLFNPLEQER.F "sp|P49641|MA2A2_HUMAN,tr|H0YNG5|H0YNG5_HUMAN,tr|H0YKT0|H0YKT0_HUMAN,tr|H0YLB9|H0YLB9_HUMAN,tr|H0YKM7|H0YKM7_HUMAN,tr|A0A0C4DGL1|A0A0C4DGL1_HUMAN" 6 1489.7929 -1 44734 21698 2 1489.787177 745.9037 Alpha-mannosidase 2x OS=Homo sapiens OX=9606 GN=MAN2A2 PE=2 SV=3 4.53 3939.3 - 699577 - - - -3.8515 - 1.942 0.072 - 169.8 2 2 0 -0.0057 12 0 0 0 0.00E+00 0.00E+00 - - - 1.1829 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.21699.21699.2 0.0962 22-Jul R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 44735 21699 2 1603.767694 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3939.5 - 571135 - - - 2.3407 - 1.704 0.267 - 126.1 1 2 0 0.0038 12 0 0 0 6.15E+06 0.00E+00 - - - 2.4142 0.9904 230117_WJC_METTL3_WT_vs_EV_F05.21703.21703.2 0.00272 22-Sep R.LFPELFTAENLR.L sp|Q5T5X7|BEND3_HUMAN 1 1448.7664 2.4 44738 21703 2 1448.774936 725.3905 BEN domain-containing protein 3 OS=Homo sapiens OX=9606 GN=BEND3 PE=1 SV=1 4.53 3939.9 - 401907 - - - 5.9154 - 1.831 0.282 - 129.7 1 2 0 0.0086 12 0 0 0 3.32E+06 1.38E+06 - - - 2.7127 0.9903 230117_WJC_METTL3_WT_vs_EV_F05.21709.21709.2 0.0349 14/20 K.LALGIPLPELR[166.11].N "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1200.747 2.43 44743 21709 2 1200.746343 601.3808 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3940.3 - 4.02E+06 - - - -0.5172 - 1.951 0.02 - 660.8 1 2 0 -0.0006 11 0 0 0 3.77E+07 1.55E+07 - - - 0.9965 1 230117_WJC_METTL3_WT_vs_EV_F05.21712.21712.2 0.000133 20-Oct K.VVLPTFILEPR.S "sp|Q9BZF1|OSBL8_HUMAN,tr|F8VUA7|F8VUA7_HUMAN,tr|F8VQX7|F8VQX7_HUMAN" 3 1282.7649 1.89 44746 21712 2 1282.76377 642.3897 Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3 5.97 3940.5 - 1.37E+06 - - - -0.8879 - 2.065 0.489 - 433.9 1 2 0 -0.0011 11 0 0 0 6.57E+06 3.47E+06 - - - 4.614 1 230117_WJC_METTL3_WT_vs_EV_F05.21713.21713.2 3.92E-06 18-Dec K.ADLTALFLPR[166.11].Q sp|Q13045|FLII_HUMAN 1 1125.6422 1.88 44747 21713 2 1125.64296 563.8284 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.88 3940.6 - 1.34E+06 - - - 0.7063 - 2.612 0.531 - 467.7 1 2 0 0.0008 10 0 0 0 1.77E+07 9.41E+06 - - - 5.6427 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21714.21714.2 0.000371 24-Nov R.NIFPSNLVSAAFR[166.11].S "sp|Q15758|AAAT_HUMAN,tr|M0QXM4|M0QXM4_HUMAN,tr|M0QX44|M0QX44_HUMAN" 3 1444.7702 1.33 44748 21714 2 1444.770672 723.3924 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 9.75 3940.7 - 1.04E+06 - - - 0.3135 - 2.086 0.476 - 209.2 1 2 0 0.0005 13 0 0 0 6.88E+06 5.18E+06 - - - 4.4436 1 230117_WJC_METTL3_WT_vs_EV_F05.21716.21716.2 0.000454 24-Dec R.NIFPSNLVSAAFR.S "sp|Q15758|AAAT_HUMAN,tr|M0QXM4|M0QXM4_HUMAN,tr|M0QX44|M0QX44_HUMAN" 3 1434.7619 1.33 44750 21716 2 1434.764519 718.3883 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 9.75 3941 - 879814 - - - 1.7912 - 2.33 0.489 - 394.1 1 2 0 0.0026 13 0 0 0 6.88E+06 5.18E+06 - - - 4.8229 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21717.21717.2 0.00286 20-Aug K.VVLPTFILEPR[166.11].S "sp|Q9BZF1|OSBL8_HUMAN,tr|F8VUA7|F8VUA7_HUMAN,tr|F8VQX7|F8VQX7_HUMAN" 3 1292.7732 -1 44751 21717 2 1292.773183 647.3939 Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3 5.97 3941.1 - 821705 - - - 0.0031 - 1.825 0.359 - 177.5 1 2 0 0 11 0 0 0 0.00E+00 0.00E+00 - - - 3.32 1 230117_WJC_METTL3_WT_vs_EV_F05.21719.21719.2 5.70E-06 15/28 R.VLAFLSSVAGDALTR[166.11].H sp|Q92616|GCN1_HUMAN 1 1528.8489 1.18 44753 21719 2 1528.850629 765.4317 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3941.3 - 695047 - - - 1.1551 - 2.943 0.579 - 747.4 1 2 0 0.0018 15 0 0 0 7.04E+06 5.99E+06 - - - 5.9708 0.9938 230117_WJC_METTL3_WT_vs_EV_F05.21721.21721.2 0.0535 16-Sep R.IGLENFLLR.L "sp|O95219|SNX4_HUMAN,tr|F8W9T3|F8W9T3_HUMAN" 2 1073.6233 1.93 44755 21721 2 1073.620958 537.8189 Sorting nexin-4 OS=Homo sapiens OX=9606 GN=SNX4 PE=1 SV=1 6 3941.5 - 392585 - - - -2.2093 - 1.371 0.32 - 166.3 1 2 0 -0.0024 9 0 0 0 1.52E+06 7.86E+05 - - - 2.3167 1 230117_WJC_METTL3_WT_vs_EV_F05.21726.21726.2 4.38E-07 13/26 K.LYSPSQIGAFVLMK[136.11].M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1560.8465 4.92 44758 21726 2 1560.848471 781.4305 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3942.1 - 3.72E+06 - - - 1.2391 - 2.773 0.593 - 531.6 1 2 0 0.0019 14 0 0 0 1.09E+08 2.21E+07 - - - 5.9798 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.21728.21728.2 0.000205 16-Sep R.NLPFDFTWK.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1166.576 2.76 44760 21728 2 1166.577754 584.2953 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3942.2 - 3.59E+06 - - - 1.4641 - 1.642 0.251 - 212.2 1 2 0 0.0017 9 0 0 0 1.61E+08 5.81E+07 - - - 2.3291 1 230117_WJC_METTL3_WT_vs_EV_F05.21732.21732.2 0.00154 17/26 K.QIALAVLSTELAVR.K "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1482.877 2.49 44764 21732 2 1482.878522 742.4458 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3942.5 - 1.72E+06 - - - 1.0405 - 3.026 0.447 - 1266.2 1 2 0 0.0015 14 0 0 0 6.91E+06 2.78E+06 - - - 5.1206 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21733.21733.2 0.496 16-Oct R.DILALMEVK.M sp|Q96EK4|THA11_HUMAN 1 1030.5733 2.3 44765 21733 2 1030.574351 516.2939 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 4.37 3942.6 - 1.54E+06 - - - 1.0509 - 1.915 0.26 - 306.1 1 2 0 0.0011 9 0 0 0 5.66E+06 2.46E+06 - - - 2.8407 1 230117_WJC_METTL3_WT_vs_EV_F05.21734.21734.2 0.00561 13/20 K.TPVLFDIYEIK.E sp|P50995|ANX11_HUMAN 1 1336.7279 3.55 44766 21734 2 1336.728538 669.3712 Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1 4.37 3942.7 - 1.39E+06 - - - 0.5109 - 2.731 0.488 - 838.5 1 2 0 0.0007 11 0 0 0 6.37E+06 1.79E+06 - - - 5.363 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21735.21735.2 0.000724 18-Dec R.LLELQYFISR[166.11].D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1290.7211 0.72 44767 21735 2 1290.723311 646.3678 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 6 3942.7 - 1.31E+06 - - - 1.6797 - 2.282 0.434 - 659.7 1 2 0 0.0022 10 0 0 0 4.60E+06 6.41E+06 - - - 4.5488 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21738.21738.2 0.00462 13/24 R.NIIGVIPYFPYSK.Q "sp|Q14558|KPRA_HUMAN,tr|C9JKT9|C9JKT9_HUMAN,tr|B4DP31|B4DP31_HUMAN,tr|C9JNQ3|C9JNQ3_HUMAN,tr|C9JUN4|C9JUN4_HUMAN,tr|C9J168|C9J168_HUMAN" 6 1509.8232 -1 44770 21738 2 1509.826972 755.9189 Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Homo sapiens OX=9606 GN=PRPSAP1 PE=1 SV=2 8.5 3943 - 1.09E+06 - - - 2.5301 - 2.131 0.315 - 401.7 1 2 0 0.0038 13 0 0 0 0.00E+00 0.00E+00 - - - 3.3082 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.21740.21740.2 0.000155 14-Jul R.DFC[160.03]FFTIK.F "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1076.5001 -1 44772 21740 2 1076.500019 539.2573 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.83 3943.2 - 1.03E+06 - - - -0.079 - 1.572 0.483 - 143 1 2 0 -0.0001 8 0 0 0 0.00E+00 0.00E+00 - - - 3.9727 0.9264 230117_WJC_METTL3_WT_vs_EV_F05.21742.21742.3 1.02 Aug-56 R.VLAFLSSVAGDALTR[166.11].H sp|Q92616|GCN1_HUMAN 1 1528.8489 0.63 44774 21742 3 1528.851519 510.6236 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3943.4 - 876039 - - - 1.7373 - 1.395 0.075 - 78.3 1 2 0 0.0027 15 0 0 0 3.12E+06 4.94E+06 - - - 0.2441 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.21743.21743.2 0.0015 15/26 K.QIALAVLSTELAVR[166.11].K "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1492.8852 -1 44775 21743 2 1492.889281 747.4499 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3943.5 - 825201 - - - 2.7008 - 1.619 0.461 - 269.3 1 2 0 0.004 14 0 0 0 0.00E+00 0.00E+00 - - - 3.6538 1 230117_WJC_METTL3_WT_vs_EV_F05.21749.21749.3 3.05E-05 Dec-52 K.LYSPSQIGAFVLMK.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1552.8323 4.73 44780 21749 3 1552.834173 518.6181 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3944.2 - 6.93E+06 - - - 1.1824 - 2.588 0.495 - 260.3 1 2 0 0.0018 14 0 0 0 2.96E+07 6.26E+06 - - - 6.5853 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21751.21751.2 0.000897 24-Nov R.LLDISASSTEQIL.- "sp|O43615|TIM44_HUMAN,tr|M0QXM9|M0QXM9_HUMAN" 2 1388.7399 - 44782 21751 2 1388.742143 695.3772 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.67 3944.3 - 4.36E+06 - - - 1.6324 - 2.066 0.383 - 371.2 1 2 0 0.0023 13 0 0 0 - - - - - 3.7314 0.9977 230117_WJC_METTL3_WT_vs_EV_F05.21752.21752.2 0.01 16-Sep R.NLPFDFTWK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1174.5902 2.77 44783 21752 2 1174.58784 588.3024 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3944.4 - 4.21E+06 - - - -2.0484 - 1.609 0.412 - 207.3 1 2 0 -0.0024 9 0 0 0 1.61E+08 5.81E+07 - - - 3.4592 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21753.21753.2 0.0527 20-Oct K.DFAPVIVEAFK.H "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1234.6598 2.22 44784 21753 2 1234.6611 618.3372 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.37 3944.4 - 3.52E+06 - - - 1.0732 - 2.007 0.465 - 300.4 1 2 0 0.0013 11 0 0 0 2.23E+07 1.00E+07 - - - 4.3597 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21754.21754.2 0.000448 13/26 K.GYAFIEFASFEDAK.E "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 10 1593.7351 0.88 44785 21754 2 1593.735957 797.8748 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.14 3944.5 - 2.36E+06 - - - 0.522 - 1.955 0.513 - 316.7 1 2 0 0.0008 14 0 0 0 1.05E+07 1.18E+07 - - - 4.5121 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.21756.21756.2 0.00717 22-Sep R.VALILQNVDLPN.- "sp|Q04446|GLGB_HUMAN,tr|E9PGM4|E9PGM4_HUMAN" 2 1307.7449 - 44787 21756 2 1307.745574 654.8797 "1,4-alpha-glucan-branching enzyme OS=Homo sapiens OX=9606 GN=GBE1 PE=1 SV=3" 3.8 3944.6 - 1.96E+06 - - - 0.5139 - 1.436 0.39 - 163.2 1 2 0 0.0007 12 0 0 0 - - - - - 2.8734 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21757.21757.2 1.87E-05 22-Nov R.TLITFAGMIPYR.T "sp|Q8N1F7|NUP93_HUMAN,tr|H3BV15|H3BV15_HUMAN" 2 1381.7428 -1 44788 21757 2 1381.74476 691.8787 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 8.41 3944.7 - 1.94E+06 - - - 1.4236 - 2.47 0.302 - 425.4 1 2 0 0.002 12 0 0 0 0.00E+00 0.00E+00 - - - 3.6501 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21758.21758.2 0.00708 18-Oct R.LLELQYFISR.D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1280.7129 -1 44789 21758 2 1280.71482 641.3637 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 6 3944.8 - 1.68E+06 - - - 1.5202 - 2.186 0.36 - 428.5 1 2 0 0.0019 10 0 0 0 0.00E+00 0.00E+00 - - - 3.8824 0.9948 230117_WJC_METTL3_WT_vs_EV_F05.21759.21759.2 1.73 14-Jul K.ISLIQIFR[166.11].A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 998.6152 0.8 44790 21759 2 998.615956 500.3149 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.75 3944.9 - 1.52E+06 - - - 0.735 - 1.608 0.073 - 119.4 1 2 0 0.0007 8 0 0 0 2.77E+06 3.45E+06 - - - 1.0125 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.21760.21760.2 0.268 14-Aug K.ISLIQIFR.A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 988.607 -1 44791 21760 2 988.609705 495.3108 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.75 3944.9 - 1.45E+06 - - - 2.7847 - 1.883 0.169 - 176.1 1 2 0 0.0028 8 0 0 0 0.00E+00 0.00E+00 - - - 2.1971 1 230117_WJC_METTL3_WT_vs_EV_F05.21761.21761.2 5.04E-07 13/22 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 261.97 44792 21761 2 1459.794243 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3945 - 1.38E+06 - - - 1.368 - 2.769 0.538 - 693.3 1 2 0 0.002 12 0 0 0 1.00E+09 3.82E+06 - - - 5.6939 0.9758 230117_WJC_METTL3_WT_vs_EV_F05.21763.21763.2 0.105 18-Sep K.ADLTALFLPR.Q sp|Q13045|FLII_HUMAN 1 1115.6339 1.88 44794 21763 2 1115.640331 558.8242 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.88 3945.2 - 951156 - - - 5.7689 - 1.61 0.178 - 167.7 1 2 0 0.0064 10 0 0 0 1.77E+07 9.41E+06 - - - 1.683 1 230117_WJC_METTL3_WT_vs_EV_F05.21764.21764.2 3.31E-08 13/24 K.MFVLDEADEMLSR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 11 1564.7141 -1 44795 21764 2 1564.714803 783.3643 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 3.92 3945.4 - 893575 - - - 0.4582 - 2.544 0.584 - 527.5 1 2 0 0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 5.7507 1 230117_WJC_METTL3_WT_vs_EV_F05.21765.21765.2 1.02E-06 18/24 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 1.9 44796 21765 2 1509.890746 755.9512 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3945.5 - 887262 - - - 1.8995 - 3.037 0.559 - 1140.3 1 2 0 0.0029 13 0 0 0 3.62E+07 1.91E+07 - - - 6.02 1 230117_WJC_METTL3_WT_vs_EV_F05.21766.21766.2 7.64E-10 18/32 R.AIGLSPMSFPTADLTLK[136.11].M "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1768.9525 -1 44797 21766 2 1768.953582 885.4835 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.88 3945.6 - 779488 - - - 0.6354 - 3.425 0.593 - 1013.4 1 2 0 0.0011 17 0 0 0 0.00E+00 0.00E+00 - - - 6.4473 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21768.21768.2 0.00809 17/28 R.ALVEVLGPYEPLLSR.V "sp|Q86VR2|RETR3_HUMAN,tr|K7EMF4|K7EMF4_HUMAN,tr|K7ELM8|K7ELM8_HUMAN,tr|K7EJ34|K7EJ34_HUMAN,tr|K7ENF4|K7ENF4_HUMAN,tr|K7ENZ6|K7ENZ6_HUMAN" 6 1654.9294 -1 44798 21768 2 1654.932538 828.472 Reticulophagy regulator 3 OS=Homo sapiens OX=9606 GN=RETREG3 PE=1 SV=1 4.53 3945.8 - 1.69E+06 - - - 1.8913 - 2.929 0.392 - 872.1 1 2 0 0.0031 15 0 0 0 0.00E+00 0.00E+00 - - - 4.5774 1 230117_WJC_METTL3_WT_vs_EV_F05.21770.21770.2 1.68E-09 18/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 4.28 44800 21770 2 1591.945759 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3946 - 2.27E+07 - - - 0.4774 - 3.088 0.671 - 749.7 1 2 0 0.0008 15 0 0 0 1.08E+08 2.52E+07 - - - 6.7688 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21771.21771.3 5.40E-06 16/56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 4.52 44801 21771 3 1591.946072 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3946 - 1.50E+07 - - - 0.674 - 3.008 0.43 - 253.1 1 2 0 0.0011 15 0 0 0 6.17E+07 1.37E+07 - - - 6.2074 1 230117_WJC_METTL3_WT_vs_EV_F05.21772.21772.2 0.000203 14/24 R.NVIVLQTVLQEVR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1519.8961 -1 44802 21772 2 1519.897031 760.9554 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3946.1 - 7.90E+06 - - - 0.581 - 2.721 0.514 - 726.3 1 2 0 0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 5.4062 1 230117_WJC_METTL3_WT_vs_EV_F05.21773.21773.3 4.84E-08 17/48 K.LFYADHPFIFLVR.D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1636.8766 3.6 44803 21773 3 1636.877088 546.6328 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3946.1 - 5.33E+06 - - - 0.3073 - 3.071 0.605 - 334.3 1 2 0 0.0005 13 0 0 0 3.71E+07 1.03E+07 - - - 8.3271 1 230117_WJC_METTL3_WT_vs_EV_F05.21778.21778.3 2.31E-05 16/56 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 4.52 44808 21778 3 1601.95502 534.9917 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3946.4 - 3.45E+06 - - - 1.093 - 2.344 0.519 - 275.5 1 2 0 0.0018 15 0 0 0 6.17E+07 1.37E+07 - - - 6.5487 1 230117_WJC_METTL3_WT_vs_EV_F05.21779.21779.3 6.64E-06 16/48 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 -1 44809 21779 3 1509.889205 504.3032 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3946.4 - 3.28E+06 - - - 0.8789 - 2.97 0.579 - 456.8 1 2 0 0.0013 13 0 0 0 0.00E+00 0.00E+00 - - - 7.9463 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21782.21782.2 0.00357 18-Nov K.LLELQELVLR.L "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|A0A087WYC0|A0A087WYC0_HUMAN" 3 1224.7442 -1 44812 21782 2 1224.745159 613.3794 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 4.53 3946.7 - 1.89E+06 - - - 0.8042 - 2.406 0.272 - 402.4 1 2 0 0.001 10 0 0 0 0.00E+00 0.00E+00 - - - 3.5004 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21783.21783.3 0.00223 14/48 R.NVIVLQTVLQEVR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1519.8961 -1 44813 21783 3 1519.896725 507.6393 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3946.8 - 1.79E+06 - - - 0.3796 - 2.714 0.43 - 349.2 1 2 0 0.0006 13 0 0 0 0.00E+00 0.00E+00 - - - 6.0409 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.21785.21785.2 0.000104 22-Nov K.LLPLVSDEVFIR.D sp|P11216|PYGB_HUMAN 1 1399.8075 3.77 44815 21785 2 1399.807139 700.911 "Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB PE=1 SV=5" 4.37 3946.9 - 1.60E+06 - - - -0.2593 - 2.022 0.308 - 405 1 2 0 -0.0004 12 0 0 0 4.48E+06 1.19E+06 - - - 3.1683 0.959 230117_WJC_METTL3_WT_vs_EV_F05.21786.21786.2 2.98 18-Jul K.VLLDIFTGVR.L sp|P49916|DNLI3_HUMAN 1 1131.6652 -1 44816 21786 2 1131.66556 566.8399 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 5.81 3947 - 1.54E+06 - - - 0.3225 - 1.101 0.092 - 60.2 5 2 0 0.0004 10 0 0 0 0.00E+00 0.00E+00 - - - -0.3233 1 230117_WJC_METTL3_WT_vs_EV_F05.21789.21789.2 1.12E-06 14/24 R.IGLFYMDNDLITR.N "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN" 2 1569.7861 -1 44818 21789 2 1569.790081 785.9003 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.21 3947.3 - 2.89E+06 - - - 2.5265 - 2.906 0.593 - 849.2 1 2 0 0.004 13 0 0 0 0.00E+00 0.00E+00 - - - 6.1576 1 230117_WJC_METTL3_WT_vs_EV_F05.21791.21791.2 1.28E-09 14/28 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 4.3 44820 21791 2 1601.954762 801.9839 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3947.4 - 7.19E+06 - - - 0.932 - 2.921 0.638 - 465.6 1 2 0 0.0015 15 0 0 0 1.14E+08 2.66E+07 - - - 6.3882 1 230117_WJC_METTL3_WT_vs_EV_F05.21793.21793.2 6.18E-06 20-Sep K.SVFGGLVNYFK.S "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1229.6445 0.98 44822 21793 2 1229.644977 615.8295 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 8.31 3947.4 - 5.27E+06 - - - 0.4213 - 1.931 0.53 - 206.1 1 2 0 0.0005 11 0 0 0 1.11E+07 1.14E+07 - - - 4.7356 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.21796.21796.2 0.0747 16-Sep K.ILNIFGVIK.G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1015.643 -1 44825 21796 2 1015.643517 508.8288 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3947.6 - 3.00E+06 - - - 0.5061 - 1.939 0.331 - 185.4 1 2 0 0.0005 9 0 0 0 0.00E+00 0.00E+00 - - - 3.4013 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21797.21797.2 0.00103 16-Nov K.ILNIFGVIK[136.11].G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1023.6572 -1 44826 21797 2 1023.657397 512.8359 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3947.7 - 2.25E+06 - - - 0.1895 - 2.153 0.398 - 283.8 1 2 0 0.0002 9 0 0 0 0.00E+00 0.00E+00 - - - 4.1991 1 230117_WJC_METTL3_WT_vs_EV_F05.21798.21798.2 6.14E-13 16/26 R.FGDPEC[160.03]QVILPLLK.S sp|P22102|PUR2_HUMAN 1 1627.8644 1.56 44827 21798 2 1627.865803 814.9395 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.37 3947.8 - 2.01E+06 - - - 0.8834 - 3.473 0.695 - 733.9 1 2 0 0.0014 14 0 0 0 6.86E+06 4.39E+06 - - - 7.2981 1 230117_WJC_METTL3_WT_vs_EV_F05.21799.21799.2 2.33E-05 24-Nov R.IGLFYMDNDLITR[166.11].N "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN" 2 1579.7944 -1 44828 21799 2 1579.794644 790.9045 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.21 3947.9 - 1.83E+06 - - - 0.1639 - 2.167 0.512 - 446.1 1 2 0 0.0003 13 0 0 0 0.00E+00 0.00E+00 - - - 4.8074 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21801.21801.2 0.00075 18-Sep R.ALSPLEEWLR.L "sp|P26640|SYVC_HUMAN,tr|A0A0G2JJT9|A0A0G2JJT9_HUMAN,tr|A2ABF4|A2ABF4_HUMAN,tr|A0A140T936|A0A140T936_HUMAN,tr|A0A140T954|A0A140T954_HUMAN,tr|A0A140T904|A0A140T904_HUMAN" 6 1212.6503 1.6 44830 21801 2 1212.650762 607.3324 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 4.53 3948 - 1.55E+06 - - - 0.4032 - 2.004 0.396 - 371.6 1 2 0 0.0005 10 0 0 0 5.39E+06 3.37E+06 - - - 3.9061 0.9877 230117_WJC_METTL3_WT_vs_EV_F05.21802.21802.2 0.258 18-Sep R.ALSPLEEWLR[166.11].L "sp|P26640|SYVC_HUMAN,tr|A0A0G2JJT9|A0A0G2JJT9_HUMAN,tr|A2ABF4|A2ABF4_HUMAN,tr|A0A140T936|A0A140T936_HUMAN,tr|A0A140T954|A0A140T954_HUMAN,tr|A0A140T904|A0A140T904_HUMAN" 6 1222.6585 -1 44831 21802 2 1222.658096 612.3365 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 4.53 3948.1 - 1.40E+06 - - - -0.3656 - 1.399 0.104 - 203.2 1 2 0 -0.0004 10 0 0 0 0.00E+00 0.00E+00 - - - 0.7462 0.9913 230117_WJC_METTL3_WT_vs_EV_F05.21803.21803.2 1.18 24-Nov K.LLLQGLMDSVEAK.Q "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN" 3 1415.7694 -1 44832 21803 2 1415.769106 708.892 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 4.37 3948.2 - 1.29E+06 - - - -0.2091 - 1.199 0.193 - 165.7 1 2 0 -0.0003 13 0 0 0 0.00E+00 0.00E+00 - - - 0.9322 1 230117_WJC_METTL3_WT_vs_EV_F05.21805.21805.2 4.37E-07 26-Nov R.IVEPYVTWGFPNLK.S "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1661.8817 -1 44834 21805 2 1661.881541 831.9481 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6 3948.4 - 1.04E+06 - - - -0.1137 - 2.293 0.585 - 301 1 2 0 -0.0002 14 0 0 0 0.00E+00 0.00E+00 - - - 5.4442 1 230117_WJC_METTL3_WT_vs_EV_F05.21807.21807.2 1.87E-08 15/26 R.IVEPYVTWGFPNLK[136.11].S "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1669.8959 -1 44836 21807 2 1669.896022 835.9552 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6 3948.6 - 931358 - - - 0.0551 - 2.559 0.596 - 643.4 1 2 0 0.0001 14 0 0 0 0.00E+00 0.00E+00 - - - 5.8009 1 230117_WJC_METTL3_WT_vs_EV_F05.21812.21812.2 0.000331 13/20 K.ILDVEIIFNER[166.11].G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1369.7481 1.48 44840 21812 2 1369.750003 685.8813 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3949.2 - 7.29E+06 - - - 1.3988 - 2.506 0.482 - 827 1 2 0 0.0019 11 0 0 0 2.83E+07 1.91E+07 - - - 5.0857 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21813.21813.3 0.000732 Dec-48 K.LFYADHPFIFLVR[166.11].D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1646.8849 3.88 44841 21813 3 1646.885155 549.9689 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3949.2 - 2.45E+06 - - - 0.1822 - 2.245 0.422 - 161.7 1 2 0 0.0003 13 0 0 0 4.06E+07 1.05E+07 - - - 5.4374 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.21814.21814.2 0.000722 14/24 R.VNILEVASGAVLR.S sp|Q12788|TBL3_HUMAN 1 1339.7823 -1 44842 21814 2 1339.781858 670.8985 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3949.3 - 2.28E+06 - - - -0.3672 - 2.743 0.397 - 553 1 2 0 -0.0005 13 0 0 0 0.00E+00 0.00E+00 - - - 4.5628 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.21816.21816.2 0.00394 24-Nov R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 44844 21816 2 1349.790254 675.9026 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3949.4 - 1.69E+06 - - - -0.2712 - 2.557 0.401 - 342.2 1 2 0 -0.0004 13 0 0 0 0.00E+00 0.00E+00 - - - 4.4122 1 230117_WJC_METTL3_WT_vs_EV_F05.21817.21817.2 1.79E-06 14/24 K.LGAGTFQLDQWLR.A sp|P50219|MNX1_HUMAN 1 1503.7834 -1 44845 21817 2 1503.785524 752.899 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 5.84 3949.5 - 1.38E+06 - - - 1.4038 - 2.77 0.484 - 631.5 1 2 0 0.0021 13 0 0 0 0.00E+00 0.00E+00 - - - 5.2301 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.21819.21819.2 0.000159 18-Sep R.LGIYTVLFER.L "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 1209.6758 -1 44847 21819 2 1209.680334 605.8452 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 6 3949.6 - 1.14E+06 - - - 3.7812 - 2.015 0.453 - 230.3 1 2 0 0.0046 10 0 0 0 0.00E+00 0.00E+00 - - - 4.3411 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21820.21820.2 0.000733 22-Nov M.VLESVVADLLNR.F sp|Q709C8|VP13C_HUMAN 1 1326.7507 -1 44848 21820 2 1326.753867 664.3826 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.37 3949.7 - 1.03E+06 - - - 2.375 - 2.302 0.421 - 467.2 1 2 0 0.0032 12 0 0 0 0.00E+00 0.00E+00 - - - 4.3433 1 230117_WJC_METTL3_WT_vs_EV_F05.21821.21821.3 7.59E-06 18/48 R.VNILEVASGAVLR.S sp|Q12788|TBL3_HUMAN 1 1339.7823 -1 44849 21821 3 1339.784235 447.6014 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3949.8 - 1.02E+06 - - - 1.4069 - 3.422 0.528 - 616.5 1 2 0 0.0019 13 0 0 0 0.00E+00 0.00E+00 - - - 7.7617 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21822.21822.3 3.91E-06 Nov-48 R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 44850 21822 3 1349.790967 450.9375 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3949.9 - 948961 - - - 0.2571 - 2.625 0.422 - 201.1 1 2 0 0.0003 13 0 0 0 0.00E+00 0.00E+00 - - - 5.8614 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.21824.21824.2 0.00133 14-Oct R.TLFLELIR.A sp|Q96GM8|TOE1_HUMAN 1 1003.6066 -1 44852 21824 2 1003.606883 502.8106 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 5.66 3950.1 - 899750 - - - 0.265 - 1.911 0.327 - 396.9 1 2 0 0.0003 8 0 0 0 0.00E+00 0.00E+00 - - - 3.4094 0.9818 230117_WJC_METTL3_WT_vs_EV_F05.21826.21826.3 0.6 Oct-40 K.ILDVEIIFNER[166.11].G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1369.7481 -1 44854 21826 3 1369.749008 457.59 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3950.3 - 817738 - - - 0.6724 - 1.509 0.128 - 128.9 1 2 0 0.0009 11 0 0 0 0.00E+00 0.00E+00 - - - 1.1357 1 230117_WJC_METTL3_WT_vs_EV_F05.21827.21827.2 1.54E-11 16/28 K.YFDTVPVAAAMC[160.03]VLK.T sp|Q15393|SF3B3_HUMAN 1 1683.8364 1.31 44855 21827 2 1683.835295 842.9255 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.83 3950.4 - 796313 - - - -0.6776 - 2.918 0.644 - 624.8 1 2 0 -0.0011 15 0 0 0 3.58E+06 2.73E+06 - - - 6.4301 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21829.21829.3 0.00747 Sep-40 K.ILDVEIIFNER.G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1359.7398 1.32 44857 21829 3 1359.741054 454.2539 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3950.6 - 730721 - - - 0.9097 - 1.679 0.307 - 145.8 1 2 0 0.0012 11 0 0 0 1.95E+06 1.48E+06 - - - 3.4345 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21835.21835.2 8.86E-05 14/24 K.LAGFLDLTEQEFR[166.11].L "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 1547.7859 -1 44862 21835 2 1547.791236 774.9002 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.14 3951.1 - 2.49E+06 - - - 3.4288 - 2.628 0.371 - 925.1 1 2 0 0.0053 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2594 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21837.21837.2 0.01 22-Nov K.SLVALLVETQMK.K "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1330.753 -1 44864 21837 2 1330.754731 666.3838 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.72 3951.2 - 2.01E+06 - - - 1.2827 - 2.558 0.344 - 424 1 2 0 0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 4.0525 1 230117_WJC_METTL3_WT_vs_EV_F05.21838.21838.2 9.79E-07 13/24 K.LAGFLDLTEQEFR.L "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 1537.7777 -1 44865 21838 2 1537.778624 769.8961 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.14 3951.3 - 1.88E+06 - - - 0.6275 - 2.886 0.533 - 727.3 1 2 0 0.001 13 0 0 0 0.00E+00 0.00E+00 - - - 5.6976 1 230117_WJC_METTL3_WT_vs_EV_F05.21839.21839.2 5.08E-07 26-Dec K.LSPVVGAVYGPELY.A "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 7 1462.7708 - 44866 21839 2 1462.773125 732.3927 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4 3951.4 - 1.73E+06 - - - 1.6018 - 2.317 0.562 - 400.7 1 1 0 0.0023 14 0 0 0 - - - - - 5.2998 1 230117_WJC_METTL3_WT_vs_EV_F05.21840.21840.2 6.56E-05 16-Sep R.LFIFETFC[160.03]R[166.11].L "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 12 1241.6142 -1 44867 21840 2 1241.616879 621.8144 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 5.99 3951.5 - 1.55E+06 - - - 2.1287 - 1.807 0.548 - 289 1 2 0 0.0026 9 0 0 0 0.00E+00 0.00E+00 - - - 4.7994 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21843.21843.2 0.000161 20-Oct K.FVSISDLLVPK.D sp|P50395|GDIB_HUMAN 1 1216.7067 2.34 44870 21843 2 1216.708107 609.3606 Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2 5.84 3951.7 - 985341 - - - 1.1359 - 1.786 0.426 - 218.4 1 2 0 0.0014 11 0 0 0 9.88E+06 4.22E+06 - - - 3.756 1 230117_WJC_METTL3_WT_vs_EV_F05.21850.21850.2 0.00013 13/26 K.LDDIFEPVLIPEPK.L "sp|Q14008|CKAP5_HUMAN,tr|H0YEK7|H0YEK7_HUMAN,tr|H0YCF6|H0YCF6_HUMAN" 3 1623.876 -1 44877 21850 2 1623.876071 812.9453 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 3.92 3952.5 - 711959 - - - 0.0585 - 2.483 0.565 - 532.1 1 2 0 0.0001 14 0 0 0 0.00E+00 0.00E+00 - - - 5.4963 0.9249 230117_WJC_METTL3_WT_vs_EV_F05.21852.21852.2 0.00451 20-Aug K.IIHDFPQFYPL.G "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 1388.7129 - 44878 21852 2 1388.713557 695.3637 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 5.08 3952.8 - 444420 - - - 0.4925 - 1.54 0.315 - 159.9 1 1 0 0.0007 11 0 0 0 - - - - - 2.5354 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21855.21855.2 0.000541 20-Dec K.GFLSGLLDNVK.Q "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1161.6394 2.26 44881 21855 2 1161.640732 581.827 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.84 3953 - 7.68E+06 - - - 1.169 - 2.422 0.398 - 396.4 1 2 0 0.0014 11 0 0 0 2.49E+07 1.10E+07 - - - 4.3732 0.9678 230117_WJC_METTL3_WT_vs_EV_F05.21856.21856.2 1.49 24-Apr K.AFTYSSTLISHK[136.11]R[166.11].L sp|A8MUV8|ZN727_HUMAN 1 1527.8164 0.001 44882 21856 2 1527.820096 764.9155 Putative zinc finger protein 727 OS=Homo sapiens OX=9606 GN=ZNF727 PE=5 SV=3 9.99 3953 - 3.96E+06 - - - 2.3884 - 0.974 0.138 - 41.6 2 2 0 0.0036 13 0 0 0 0.00E+00 2.97E+07 - - - -0.143 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.21860.21860.2 0.000605 20-Sep K.LILPELGPVFK[136.11].Q "sp|Q6P3W7|SCYL2_HUMAN,tr|H0YIK6|H0YIK6_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 1232.7624 0.72 44886 21860 2 1232.763905 617.3885 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6 3953.2 - 2.64E+06 - - - 1.2241 - 1.728 0.379 - 263.5 1 2 0 0.0015 11 0 0 0 3.40E+07 4.73E+07 - - - 3.3195 0.9697 230117_WJC_METTL3_WT_vs_EV_F05.21862.21862.2 0.833 20-Jul R.VTWEPAPGEVK.G "sp|Q99715|COCA1_HUMAN,tr|D6RGG3|D6RGG3_HUMAN" 2 1211.6186 5354.32 44888 21862 2 1211.617466 606.8166 Collagen alpha-1(XII) chain OS=Homo sapiens OX=9606 GN=COL12A1 PE=1 SV=2 4.53 3953.4 - 1.74E+06 - - - -0.9681 - 1.323 0.077 - 175.6 1 2 0 -0.0012 11 0 0 0 3.50E+08 6.53E+04 - - - 0.3666 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21863.21863.2 0.0651 20-Nov K.DVLLPWYNAYR.F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1408.7139 -1 44889 21863 2 1408.716039 705.3642 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3953.5 - 1.48E+06 - - - 1.4929 - 2.228 0.447 - 411.8 1 2 0 0.0021 11 0 0 0 0.00E+00 0.00E+00 - - - 4.5091 1 230117_WJC_METTL3_WT_vs_EV_F05.21865.21865.2 0.000137 13/22 R.ANLGVFSVFAPR[166.11].G "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1286.7011 0.91 44891 21865 2 1286.702065 644.3578 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 9.79 3953.6 - 1.22E+06 - - - 0.7679 - 2.65 0.479 - 702 1 2 0 0.001 12 0 0 0 5.81E+06 6.35E+06 - - - 5.1428 1 230117_WJC_METTL3_WT_vs_EV_F05.21867.21867.2 0.000252 13/22 K.SLVALLVETQMK[136.11].K "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1338.7672 1.45 44893 21867 2 1338.769931 670.3909 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.72 3953.9 - 941844 - - - 2.022 - 2.866 0.49 - 694.9 1 2 0 0.0027 12 0 0 0 7.24E+06 5.01E+06 - - - 5.4297 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21868.21868.3 6.10E-05 14/48 R.IESILMSLPLTAR[166.11].W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1452.825 1.37 44894 21868 3 1452.826083 485.2823 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3954 - 888167 - - - 0.775 - 2.874 0.405 - 268.9 1 2 0 0.0011 13 0 0 0 6.45E+06 4.70E+06 - - - 5.9174 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21869.21869.3 0.0009 13/48 R.IESILMSLPLTAR.W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1442.8167 1.37 44895 21869 3 1442.817859 481.9462 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3954.1 - 756674 - - - 0.8123 - 2.587 0.285 - 216 1 2 0 0.0012 13 0 0 0 6.45E+06 4.70E+06 - - - 4.2942 0.9981 230117_WJC_METTL3_WT_vs_EV_F05.21870.21870.2 0.0563 26-Sep K.LDDIFEPVLIPEPK[136.11].L "sp|Q14008|CKAP5_HUMAN,tr|H0YEK7|H0YEK7_HUMAN,tr|H0YCF6|H0YCF6_HUMAN" 3 1631.8902 -1 44896 21870 2 1631.891078 816.9524 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 3.92 3954.3 - 631204 - - - 0.5527 - 1.346 0.288 - 120.5 1 2 0 0.0009 14 0 0 0 0.00E+00 0.00E+00 - - - 1.9135 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.21877.21877.2 0.000114 13/24 R.IESILMSLPLTAR[166.11].W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1452.825 1.41 44902 21877 2 1452.825187 727.4198 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3954.9 - 3.17E+06 - - - 0.1583 - 2.596 0.307 - 746.4 1 2 0 0.0002 13 0 0 0 1.78E+07 1.26E+07 - - - 3.7568 1 230117_WJC_METTL3_WT_vs_EV_F05.21882.21882.2 0.000327 20-Dec K.DVLLPWYNAYR[166.11].F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1418.7222 1.34 44907 21882 2 1418.725505 710.3684 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3955.2 - 1.38E+06 - - - 2.3253 - 2.259 0.529 - 498.1 1 2 0 0.0033 11 0 0 0 6.39E+06 4.78E+06 - - - 5.1517 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21883.21883.3 1.75E-06 15/60 K.INEAIVAVQAIIADPK[136.11].T sp|Q9Y224|RTRAF_HUMAN 1 1671.9651 1.54 44908 21883 3 1671.963157 558.329 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3955.3 - 1.35E+06 - - - -1.1454 - 2.852 0.474 - 173.2 1 2 0 -0.0019 16 0 0 0 7.71E+06 5.02E+06 - - - 6.5132 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21884.21884.3 1.91E-05 20/60 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 1.54 44909 21884 3 1663.94762 555.6576 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3955.4 - 1.18E+06 - - - -1.9544 - 3.394 0.524 - 406.1 1 2 0 -0.0033 16 0 0 0 7.71E+06 5.02E+06 - - - 7.5167 1 230117_WJC_METTL3_WT_vs_EV_F05.21890.21890.2 0.0012 22-Dec K.GVNSYPSLFIFR.S "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0TB22|A0A7P0TB22_HUMAN,tr|A0A7P0Z4F2|A0A7P0Z4F2_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN,tr|E7EP04|E7EP04_HUMAN,tr|A0A7P0T9B7|A0A7P0T9B7_HUMAN,tr|A0A494C1G5|A0A494C1G5_HUMAN,tr|A0A7P0TB83|A0A7P0TB83_HUMAN" 10 1398.7296 1.64 44915 21890 2 1398.73203 700.3721 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 8.75 3956 - 749170 - - - 1.7473 - 2.564 0.497 - 359.3 1 2 0 0.0024 12 0 0 0 1.18E+07 7.23E+06 - - - 5.1885 1 230117_WJC_METTL3_WT_vs_EV_F05.21891.21891.2 6.66E-05 18/30 K.INEAIVAVQAIIADPK[136.11].T sp|Q9Y224|RTRAF_HUMAN 1 1671.9651 1.43 44916 21891 2 1671.964858 836.9898 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3956.2 - 570630 - - - -0.128 - 3.503 0.526 - 883.4 1 2 0 -0.0002 16 0 0 0 6.33E+06 4.41E+06 - - - 6.0081 1 230117_WJC_METTL3_WT_vs_EV_F05.21896.21896.2 2.10E-05 18-Dec K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 999 44920 21896 2 1146.628191 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3956.7 - 1.29E+07 - - - -0.2477 - 2.177 0.522 - 420.2 1 2 0 -0.0003 10 0 0 0 9.71E+07 0.00E+00 - - - 5.0679 1 230117_WJC_METTL3_WT_vs_EV_F05.21897.21897.2 5.66E-13 19/34 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 8.6 44921 21897 2 1911.945469 956.9806 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3956.7 - 6.11E+06 - - - -0.5785 - 3.784 0.67 - 1350.5 1 2 0 -0.0011 18 0 0 0 9.64E+07 1.12E+07 - - - 7.2611 1 230117_WJC_METTL3_WT_vs_EV_F05.21901.21901.2 2.11E-07 13/28 K.YFLVGAGAIGC[160.03]ELLK.N sp|P22314|UBA1_HUMAN 1 1609.8538 -1 44925 21901 2 1609.856268 805.9342 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.99 3957.1 - 1.26E+06 - - - 1.5324 - 2.545 0.477 - 375 1 2 0 0.0025 15 0 0 0 0.00E+00 0.00E+00 - - - 4.86 1 230117_WJC_METTL3_WT_vs_EV_F05.21902.21902.3 6.29E-07 14/52 K.LLPVLVHTFWIDTK.N sp|Q13505|MTX1_HUMAN 1 1680.9603 1.35 44926 21902 3 1680.965948 561.3274 Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1 PE=1 SV=3 6.74 3957.1 - 1.23E+06 - - - 3.3517 - 2.653 0.587 - 219.9 1 2 0 0.0056 14 0 0 0 3.65E+06 2.72E+06 - - - 7.6758 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21904.21904.2 0.000318 18-Sep K.DWVFLNYTYK[136.11].R "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN" 2 1355.6641 0.12 44928 21904 2 1355.66529 678.8393 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.83 3957.4 - 978786 - - - 0.849 - 1.905 0.391 - 307 1 2 0 0.0012 10 0 0 0 1.11E+06 9.59E+06 - - - 3.7275 1 230117_WJC_METTL3_WT_vs_EV_F05.21907.21907.3 1.77E-08 17/68 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 5.89 44929 21907 3 1911.946935 638.3228 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3957.8 - 3.50E+06 - - - 0.1883 - 3.008 0.589 - 304.4 1 2 0 0.0004 18 0 0 0 1.54E+07 2.62E+06 - - - 7.849 1 230117_WJC_METTL3_WT_vs_EV_F05.21909.21909.2 1.06E-12 19/34 K.LGGSLADSYLDEGFLLDK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1919.9608 -1 44931 21909 2 1919.958842 960.9877 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3958 - 2.55E+06 - - - -1.0068 - 3.83 0.687 - 1504.6 1 2 0 -0.0019 18 0 0 0 0.00E+00 0.00E+00 - - - 7.4161 0.9435 230117_WJC_METTL3_WT_vs_EV_F05.21913.21913.2 0.0405 18-Sep K.ANINVENAFF.T sp|P61006|RAB8A_HUMAN 1 1137.5455 - 44935 21913 2 1137.547341 569.78 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 4 3958.4 - 1.27E+06 - - - 1.6413 - 1.656 0.308 - 144.8 1 1 0 0.0019 10 0 0 0 - - - - - 2.7232 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.21917.21917.2 4.09E-07 16-Dec R.C[160.03]LLAYFLDK.S "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1141.5842 0.66 44937 21917 2 1141.585032 571.7994 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 5.83 3958.9 - 2.39E+06 - - - 0.7568 - 2.395 0.354 - 501.7 1 2 0 0.0009 9 0 0 0 8.18E+06 1.23E+07 - - - 4.1821 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.21919.21919.2 1.72E-05 13/22 R.LTLAELNQILYR[166.11].C sp|P35573|GDE_HUMAN 1 1455.8325 1.55 44939 21919 2 1455.831756 728.9235 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 6 3959 - 1.75E+06 - - - -0.5007 - 2.752 0.305 - 936.1 1 2 0 -0.0007 12 0 0 0 1.15E+07 7.41E+06 - - - 3.9571 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21920.21920.3 0.0029 15/44 R.FFALPYVDHFLR[166.11].L sp|Q9HD33|RM47_HUMAN 1 1533.8008 0.84 44940 21920 3 1533.801819 512.2742 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 6.74 3959.2 - 1.61E+06 - - - 0.6702 - 2.452 0.457 - 227.8 1 2 0 0.001 12 0 0 0 7.28E+06 8.69E+06 - - - 6.1209 1 230117_WJC_METTL3_WT_vs_EV_F05.21921.21921.2 3.13E-11 15/28 K.AVLDSYEYFAVLAAK.E sp|P82664|RT10_HUMAN 1 1658.8556 -1 44941 21921 2 1658.85579 830.4351 "28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2" 4.37 3959.3 - 1.06E+06 - - - 0.1296 - 3.184 0.69 - 669 1 2 0 0.0002 15 0 0 0 0.00E+00 0.00E+00 - - - 6.9846 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.21922.21922.3 2.35E-06 15/44 R.FFALPYVDHFLR.L sp|Q9HD33|RM47_HUMAN 1 1523.7925 0.85 44942 21922 3 1523.787434 508.9381 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 6.74 3959.4 - 1.04E+06 - - - -3.3384 - 2.529 0.419 - 242.8 1 2 0 -0.0051 12 0 0 0 7.28E+06 8.57E+06 - - - 5.7818 0.9986 230117_WJC_METTL3_WT_vs_EV_F05.21928.21928.2 0.00346 16-Jul K.IIWEDIFPK.L sp|P35573|GDE_HUMAN 1 1159.6277 2.27 44948 21928 2 1159.631631 580.8211 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 4.37 3960.2 - 626203 - - - 3.3494 - 1.646 0.34 - 108.8 1 2 0 0.0039 9 0 0 0 2.35E+07 1.03E+07 - - - 2.9928 0.9763 230117_WJC_METTL3_WT_vs_EV_F05.21929.21929.2 0.0572 24-Jul R.MNTLQAIWMMDPK.D "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 3 1577.7404 -1 44949 21929 2 1577.736305 789.8775 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.59 3960.3 - 623865 - - - -2.6126 - 1.17 0.255 - 103.8 1 2 0 -0.0041 13 0 0 0 0.00E+00 0.00E+00 - - - 1.3261 1 230117_WJC_METTL3_WT_vs_EV_F05.21935.21935.2 3.57E-07 Sep-36 R.LPVDYYGIPFAAPTALASR.D sp|Q5T6F2|UBAP2_HUMAN 1 2021.0622 -1 44955 21935 2 2021.06203 1011.5384 Ubiquitin-associated protein 2 OS=Homo sapiens OX=9606 GN=UBAP2 PE=1 SV=1 5.83 3961.1 - 397163 - - - -0.0905 - 2.022 0.543 - 82.2 1 2 0 -0.0002 19 0 0 0 0.00E+00 0.00E+00 - - - 4.7826 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.21941.21941.2 0.000617 20-Oct K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 999 44959 21941 2 1106.545486 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3961.6 - 4.95E+06 - - - -0.8278 - 2.118 0.464 - 265.4 1 2 0 -0.0009 11 0 0 0 2.92E+07 0.00E+00 - - - 4.498 1 230117_WJC_METTL3_WT_vs_EV_F05.21951.21951.2 5.36E-05 20-Oct R.FDMVQLIDVAR.Q sp|P10398|ARAF_HUMAN 1 1305.6751 -1 44969 21951 2 1305.677663 653.8448 Serine\threonine-protein kinase A-Raf OS=Homo sapiens OX=9606 GN=ARAF PE=1 SV=2 4.21 3962.7 - 538417 - - - 1.9568 - 1.986 0.538 - 256.1 1 2 0 0.0026 11 0 0 0 0.00E+00 0.00E+00 - - - 4.87 1 230117_WJC_METTL3_WT_vs_EV_F05.21956.21956.2 4.60E-09 14/26 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.33 44972 21956 2 1676.89739 839.4565 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3963.3 - 4.02E+07 - - - -0.6631 - 3.099 0.577 - 705.5 1 2 0 -0.0011 14 0 0 0 1.00E+08 7.55E+07 - - - 6.1408 1 230117_WJC_METTL3_WT_vs_EV_F05.21957.21957.2 1.05E-08 16/26 M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 1.33 44973 21957 2 1686.90618 844.4607 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3963.4 - 2.99E+07 - - - -0.3509 - 3.068 0.624 - 812.5 1 2 0 -0.0006 14 0 0 0 1.00E+08 7.55E+07 - - - 6.4628 1 230117_WJC_METTL3_WT_vs_EV_F05.21960.21960.3 3.82E-06 14/52 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.25 44976 21960 3 1676.899332 559.9734 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3963.5 - 1.18E+07 - - - 0.495 - 2.891 0.579 - 263.5 1 2 0 0.0008 14 0 0 0 2.43E+07 1.95E+07 - - - 7.8163 1 230117_WJC_METTL3_WT_vs_EV_F05.21961.21961.2 1.21E-09 22-Dec K.LIC[160.03]C[160.03]DILDVLDK.H "sp|P62258|1433E_HUMAN,tr|K7EIT4|K7EIT4_HUMAN" 2 1475.7364 -1 44977 21961 2 1475.735036 738.8755 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 3.93 3963.5 - 9.69E+06 - - - -0.9162 - 2.477 0.65 - 392.9 1 2 0 -0.0014 12 0 0 0 0.00E+00 0.00E+00 - - - 6.2281 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21962.21962.3 1.01E-06 Dec-52 M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 -1 44978 21962 3 1686.906506 563.3095 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3963.6 - 9.19E+06 - - - -0.1577 - 2.616 0.473 - 196.7 1 2 0 -0.0003 14 0 0 0 0.00E+00 0.00E+00 - - - 6.369 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21963.21963.2 4.45E-05 14/26 K.VPGLPTPIENMILR.Y "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1548.8698 -1 44979 21963 2 1548.869357 775.4422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3963.6 - 6.85E+06 - - - -0.2763 - 2.342 0.459 - 501.5 1 2 0 -0.0004 14 0 0 0 0.00E+00 0.00E+00 - - - 4.5666 0.9566 230117_WJC_METTL3_WT_vs_EV_F05.21964.21964.2 0.68 20-May K.DLTNVQNLQK[136.11]K[136.11].H "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1315.7431 -1 44980 21964 2 1315.741553 658.8788 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.59 3963.7 - 5.61E+06 - - - -1.1484 - 0.878 0.204 - 31.5 1 2 0 -0.0015 11 0 0 0 0.00E+00 0.00E+00 - - - 0.1953 1 230117_WJC_METTL3_WT_vs_EV_F05.21967.21967.2 6.35E-07 17/26 K.MQLMELAILNGTYR.D "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1651.8426 2.42 44983 21967 2 1651.840644 826.9286 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 5.75 3964 - 4.34E+06 - - - -1.1744 - 2.95 0.608 - 889.4 1 2 0 -0.0019 14 0 0 0 1.23E+07 5.09E+06 - - - 6.2458 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.21968.21968.2 0.0088 16-Nov K.AGLVELLLR.E "sp|Q13425|SNTB2_HUMAN,tr|A0A140TA73|A0A140TA73_HUMAN" 2 982.6175 -1 44984 21968 2 982.617042 492.316 Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1 6.05 3964.1 - 4.26E+06 - - - -0.4824 - 2.453 0.378 - 398.5 1 2 0 -0.0005 9 0 0 0 0.00E+00 0.00E+00 - - - 4.4287 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21969.21969.2 2.15E-05 17/24 R.ALTLGALTLPLAR.L sp|Q9BSJ8|ESYT1_HUMAN 1 1308.8129 -1 44985 21969 2 1308.811555 655.4137 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 9.79 3964.2 - 3.11E+06 - - - -1.0445 - 2.78 0.38 - 1142.2 1 2 0 -0.0014 13 0 0 0 0.00E+00 0.00E+00 - - - 4.4714 0.9974 230117_WJC_METTL3_WT_vs_EV_F05.21972.21972.2 0.087 20-Jul R.LDNTLEEIIFK.L sp|Q86SE9|PCGF5_HUMAN 1 1333.7129 -1 44988 21972 2 1333.714269 667.8637 Polycomb group RING finger protein 5 OS=Homo sapiens OX=9606 GN=PCGF5 PE=1 SV=1 4.14 3964.5 - 2.31E+06 - - - 1.0017 - 1.284 0.244 - 95 1 2 0 0.0013 11 0 0 0 0.00E+00 0.00E+00 - - - 1.519 0.9911 230117_WJC_METTL3_WT_vs_EV_F05.21973.21973.3 0.0767 Nov-72 -.MLLDAGPQFPAIGVGSFAR.H sp|O95409|ZIC2_HUMAN 1 1946.0084 -1 44989 21973 3 1946.009372 649.6767 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 5.59 3964.6 - 1.91E+06 - - - 0.4974 - 1.659 0.167 - 67 1 2 0 0.001 19 0 0 0 0.00E+00 0.00E+00 - - - 1.6453 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21974.21974.2 2.47E-05 13/26 R.VGVDPLIIPTDYWK.K "sp|Q9NQW7|XPP1_HUMAN,tr|Q5T6H2|Q5T6H2_HUMAN,tr|Q5T6H3|Q5T6H3_HUMAN,tr|Q5T6H7|Q5T6H7_HUMAN" 4 1614.8657 -1 44990 21974 2 1614.865833 808.4401 Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3 4.21 3964.7 - 1.89E+06 - - - 0.0545 - 2.145 0.442 - 266.4 1 2 0 0.0001 14 0 0 0 0.00E+00 0.00E+00 - - - 4.2206 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.21975.21975.3 3.56E-05 13/52 K.MQLMELAILNGTYR.D "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1651.8426 1.47 44991 21975 3 1651.839801 551.6215 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 5.75 3964.8 - 1.80E+06 - - - -1.6848 - 2.15 0.514 - 181.6 1 2 0 -0.0028 14 0 0 0 5.30E+06 3.60E+06 - - - 6.3041 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.21978.21978.2 5.09E-05 20-Dec K.TFSFAIPLIEK.L sp|Q9NR30|DDX21_HUMAN 1 1264.7067 0.95 44993 21978 2 1264.705727 633.3606 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.66 3965 - 1.52E+07 - - - -0.7891 - 1.938 0.5 - 318 1 2 0 -0.001 11 0 0 0 5.90E+07 6.21E+07 - - - 4.5236 1 230117_WJC_METTL3_WT_vs_EV_F05.21979.21979.2 1.12E-06 20-Dec K.TFSFAIPLIEK[136.11].L sp|Q9NR30|DDX21_HUMAN 1 1272.7209 0.95 44994 21979 2 1272.720485 637.3677 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.66 3965.1 - 1.60E+07 - - - -0.3457 - 2.015 0.573 - 344.4 1 2 0 -0.0004 11 0 0 0 5.90E+07 6.21E+07 - - - 5.1684 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.21980.21980.2 0.00407 16-Aug R.FLILPDMLK[136.11].N sp|P62318|SMD3_HUMAN 1 1096.6446 -1 44995 21980 2 1096.644688 549.3296 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.84 3965.1 - 8.98E+06 - - - 0.0903 - 1.615 0.385 - 172.2 1 2 0 0.0001 9 0 0 0 0.00E+00 0.00E+00 - - - 3.2713 1 230117_WJC_METTL3_WT_vs_EV_F05.21981.21981.2 0.00162 13/22 R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 -1 44996 21981 2 1328.718182 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3965.2 - 7.39E+06 - - - -0.4252 - 2.447 0.493 - 444.6 1 2 0 -0.0006 12 0 0 0 0.00E+00 0.00E+00 - - - 5.0367 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21984.21984.3 0.00171 16/44 K.C[160.03]LVFSLIGLHFK[136.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1440.8043 -1 44999 21984 3 1440.804485 481.2754 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3965.3 - 2.69E+06 - - - 0.1437 - 2.437 0.409 - 343.9 1 2 0 0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 5.569 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.21985.21985.2 0.0311 20-Aug K.LVPDLLAIVQR.K "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1235.7602 1.3 45000 21985 2 1235.760875 618.8874 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.84 3965.4 - 2.06E+06 - - - 0.5802 - 1.547 0.338 - 239.1 1 2 0 0.0007 11 0 0 0 6.79E+06 5.21E+06 - - - 2.7176 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.21986.21986.3 0.00018 15/44 K.C[160.03]LVFSLIGLHFK.L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1432.7901 0.96 45001 21986 3 1432.789832 478.604 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3965.4 - 1.92E+06 - - - -0.1717 - 2.468 0.428 - 368.4 1 2 0 -0.0002 12 0 0 0 8.66E+06 9.03E+06 - - - 5.8158 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.21989.21989.2 1.84E-05 14-Sep R.C[160.03]FLSWLVK.L sp|Q92900|RENT1_HUMAN 1 1051.5525 0.31 45004 21989 2 1051.553164 526.7835 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.22 3965.7 - 1.08E+06 - - - 0.6562 - 1.844 0.405 - 317.3 1 2 0 0.0007 8 0 0 0 4.37E+06 1.42E+07 - - - 3.8777 0.9951 230117_WJC_METTL3_WT_vs_EV_F05.21990.21990.2 0.0157 26-Aug K.VPGLPTPIENMILR[166.11].Y "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1558.8781 -1 45005 21990 2 1558.876363 780.4463 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3965.8 - 1.06E+06 - - - -1.0854 - 1.476 0.25 - 101 1 2 0 -0.0017 14 0 0 0 0.00E+00 0.00E+00 - - - 1.864 0.9888 230117_WJC_METTL3_WT_vs_EV_F05.21993.21993.2 0.334 24-Nov R.IASGLGLAWIVGR[166.11].V "sp|O14880|MGST3_HUMAN,tr|Q5VV87|Q5VV87_HUMAN,tr|Q5VV89|Q5VV89_HUMAN" 3 1321.7746 -1 45008 21993 2 1321.773081 661.8946 Microsomal glutathione S-transferase 3 OS=Homo sapiens OX=9606 GN=MGST3 PE=1 SV=1 9.75 3966.2 - 1.80E+06 - - - -1.1311 - 1.588 0.129 - 367.7 1 2 0 -0.0015 13 0 0 0 0.00E+00 0.00E+00 - - - 1.1803 1 230117_WJC_METTL3_WT_vs_EV_F05.21999.21999.2 1.34E-09 18/34 K.LLGTIYTAAEEIEAVGGK.A sp|Q6YN16|HSDL2_HUMAN 1 1833.9724 -1 45013 21999 2 1833.977091 917.9935 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3966.9 - 1.95E+06 - - - 2.5606 - 3.835 0.678 - 1131.8 1 2 0 0.0047 18 0 0 0 0.00E+00 0.00E+00 - - - 7.3519 1 230117_WJC_METTL3_WT_vs_EV_F05.22001.22001.2 0.000114 22-Dec R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 -1 45015 22001 2 1301.708041 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3967 - 5.61E+06 - - - 0.1483 - 2.625 0.536 - 376.7 1 2 0 0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 5.5391 1 230117_WJC_METTL3_WT_vs_EV_F05.22002.22002.3 1.96E-06 14/68 K.LLGTIYTAAEEIEAVGGK.A sp|Q6YN16|HSDL2_HUMAN 1 1833.9724 3.6 45016 22002 3 1833.97435 612.3314 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3967 - 3.03E+06 - - - 1.066 - 2.783 0.493 - 294.8 1 2 0 0.002 18 0 0 0 5.78E+06 1.61E+06 - - - 6.5846 0.9928 230117_WJC_METTL3_WT_vs_EV_F05.22005.22005.2 0.316 12-Jun K.DVLDSVL.- sp|P81605|DCD_HUMAN 1 759.4014 - 45019 22005 2 759.40104 380.708 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.56 3967.2 - 1.89E+06 - - - -0.5201 - 1.263 0.196 - 131.9 1 2 0 -0.0004 7 0 0 0 - - - - - 1.2284 1 230117_WJC_METTL3_WT_vs_EV_F05.22006.22006.2 0.0169 20-Nov K.LVLADLLEPVK.T sp|Q9BVJ6|UT14A_HUMAN 1 1208.738 1.77 45020 22006 2 1208.74387 605.3763 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3967.3 - 1.76E+06 - - - 4.8348 - 2.207 0.484 - 301.7 1 2 0 0.0058 11 0 0 0 2.03E+07 1.14E+07 - - - 4.7555 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22007.22007.2 1.45E-05 18-Oct K.GGFDWNLVFK.W sp|Q10471|GALT2_HUMAN 1 1181.5869 -1 45021 22007 2 1181.587892 591.8007 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.84 3967.3 - 1.75E+06 - - - 0.8015 - 1.845 0.511 - 210.7 1 2 0 0.0009 10 0 0 0 0.00E+00 0.00E+00 - - - 4.5246 0.8913 230117_WJC_METTL3_WT_vs_EV_F05.22012.22012.2 5.46 12-Jun K.NIFLLFK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 893.5375 -1 45026 22012 2 893.536928 447.776 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.75 3967.7 - 1.36E+06 - - - -0.6122 - 1.15 0 - 157 2 2 0 -0.0005 7 0 0 0 0.00E+00 0.00E+00 - - - -0.6508 1 230117_WJC_METTL3_WT_vs_EV_F05.22017.22017.2 7.92E-09 Nov-34 K.LLGTIYTAAEEIEAVGGK[136.11].A sp|Q6YN16|HSDL2_HUMAN 1 1841.9866 -1 45031 22017 2 1841.984949 922.0006 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3968.3 - 681356 - - - -0.8936 - 2.38 0.577 - 342.4 1 2 0 -0.0016 18 0 0 0 0.00E+00 0.00E+00 - - - 5.434 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.22022.22022.2 0.000214 20-Dec K.LVLADLLEPVK[136.11].T sp|Q9BVJ6|UT14A_HUMAN 1 1216.7522 -1 45035 22022 2 1216.753188 609.3834 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3968.9 - 4.63E+06 - - - 0.7906 - 2.128 0.38 - 359.2 1 2 0 0.001 11 0 0 0 0.00E+00 0.00E+00 - - - 3.8903 1 230117_WJC_METTL3_WT_vs_EV_F05.22028.22028.2 8.46E-05 13/22 K.QFEELTLGEFLK.L "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1452.75 -1 45041 22028 2 1452.751634 727.3823 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.25 3969.5 - 1.85E+06 - - - 1.0924 - 2.586 0.487 - 754.7 1 2 0 0.0016 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1374 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22029.22029.2 0.00961 14/24 K.IPLKPPPLELLNV.- sp|O15504|NUP42_HUMAN 1 1441.8908 1.89 45042 22029 2 1441.892018 721.9527 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 3969.6 - 1.80E+06 - - - 0.8184 - 2.09 0.411 - 664.1 1 2 0 0.0012 13 0 0 0 6.62E+06 3.50E+06 - - - 3.9682 1 230117_WJC_METTL3_WT_vs_EV_F05.22031.22031.2 3.10E-06 22-Dec K.GDLDLELVLLC[160.03]K[136.11].E "sp|Q12906|ILF3_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 1394.7571 -1 45044 22031 2 1394.759739 698.3858 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.03 3969.9 - 1.62E+06 - - - 1.9258 - 2.698 0.565 - 562 1 2 0 0.0027 12 0 0 0 0.00E+00 0.00E+00 - - - 5.8247 0.8846 230117_WJC_METTL3_WT_vs_EV_F05.22035.22035.3 1.32 Oct-56 K.NLAEALLTYETLDAK.E sp|Q96TA2|YMEL1_HUMAN 1 1663.8669 1.35 45048 22035 3 1663.865769 555.6296 ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX=9606 GN=YME1L1 PE=1 SV=2 4.14 3970.4 - 1.13E+06 - - - -0.6605 - 1.394 0.086 - 101.6 1 2 0 -0.0011 15 0 0 0 1.96E+06 1.46E+06 - - - 0.3653 0.9914 230117_WJC_METTL3_WT_vs_EV_F05.22042.22042.2 0.000266 14-Jul R.GFGFILFK[136.11].D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 935.536 0.87 45054 22042 2 935.535034 468.7753 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3971.1 - 4.77E+06 - - - -1.0593 - 1.383 0.181 - 145 1 2 0 -0.001 8 0 0 0 4.42E+07 5.06E+07 - - - 1.3555 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.22043.22043.2 0.0127 18-Nov K.STLLLLLTGK[136.11].L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1065.6889 -1 45055 22043 2 1065.68891 533.8517 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3971.1 - 4.58E+06 - - - 0.0122 - 2.24 0.433 - 455.6 1 2 0 0 10 0 0 0 0.00E+00 0.00E+00 - - - 4.4903 1 230117_WJC_METTL3_WT_vs_EV_F05.22044.22044.2 3.71E-05 18-Oct K.STLLLLLTGK.L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1057.6747 -1 45056 22044 2 1057.675367 529.8446 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3971.2 - 4.34E+06 - - - 0.6335 - 2.024 0.582 - 335.5 1 2 0 0.0007 10 0 0 0 0.00E+00 0.00E+00 - - - 5.3075 0.9943 230117_WJC_METTL3_WT_vs_EV_F05.22045.22045.2 0.194 14-Aug K.GSLLDFLK.E "sp|P07947|YES_HUMAN,sp|P09769|FGR_HUMAN,sp|P07948|LYN_HUMAN,sp|P08631|HCK_HUMAN,sp|P06241|FYN_HUMAN,sp|P12931|SRC_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|J3QRU1|J3QRU1_HUMAN" 9 891.5066 -1 45057 22045 2 891.506324 446.7606 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 3971.2 - 3.23E+06 - - - -0.2748 - 1.467 0.149 - 218 1 2 0 -0.0002 8 0 0 0 0.00E+00 0.00E+00 - - - 1.2972 0.9933 230117_WJC_METTL3_WT_vs_EV_F05.22046.22046.2 0.018 14-Jul R.GFGFILFK.D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 927.5218 0.87 45058 22046 2 927.521274 464.7682 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3971.3 - 2.60E+06 - - - -0.5941 - 1.373 0.179 - 148.9 1 2 0 -0.0006 8 0 0 0 4.42E+07 5.06E+07 - - - 1.319 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.22047.22047.2 0.537 16-Aug R.VNILFDFVK[136.11].K sp|P55010|IF5_HUMAN 1 1101.6314 -1 45059 22047 2 1101.630659 551.823 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.81 3971.4 - 1.93E+06 - - - -0.6563 - 1.592 0.185 - 196.4 1 2 0 -0.0007 9 0 0 0 0.00E+00 0.00E+00 - - - 1.7524 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22048.22048.2 0.00792 16-Oct R.VNILFDFVK.K sp|P55010|IF5_HUMAN 1 1093.6172 -1 45060 22048 2 1093.618444 547.8159 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.81 3971.4 - 1.80E+06 - - - 1.154 - 2.091 0.365 - 404.5 1 2 0 0.0013 9 0 0 0 0.00E+00 0.00E+00 - - - 3.8705 1 230117_WJC_METTL3_WT_vs_EV_F05.22050.22050.2 0.00515 18-Sep K.ILYDILAFAK.E "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1165.6747 -1 45062 22050 2 1165.67488 583.8446 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.83 3971.6 - 1.66E+06 - - - 0.157 - 2.036 0.49 - 185.7 1 2 0 0.0002 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6447 1 230117_WJC_METTL3_WT_vs_EV_F05.22051.22051.2 0.00218 24-Dec R.LLSLISIALPENK.V "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1409.8494 2.71 45063 22051 2 1409.850577 705.932 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 6 3971.6 - 1.36E+06 - - - 0.8582 - 2.665 0.49 - 433.1 1 2 0 0.0012 13 0 0 0 4.44E+06 1.64E+06 - - - 5.1755 1 230117_WJC_METTL3_WT_vs_EV_F05.22052.22052.2 7.30E-05 20-Oct R.LWGLTEMFPER.V sp|Q9NS69|TOM22_HUMAN 1 1377.6751 1.72 45064 22052 2 1377.676505 689.8448 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 4.53 3971.7 - 1.35E+06 - - - 1.014 - 2.023 0.494 - 374.3 1 2 0 0.0014 11 0 0 0 1.06E+07 6.16E+06 - - - 4.5953 1 230117_WJC_METTL3_WT_vs_EV_F05.22053.22053.2 3.48E-05 14/24 R.VSELQVLLGYAGR.N "sp|O75925|PIAS1_HUMAN,tr|H3BSI8|H3BSI8_HUMAN" 2 1403.7773 -1 45065 22053 2 1403.777186 702.8959 E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=9606 GN=PIAS1 PE=1 SV=2 5.97 3971.8 - 1.03E+06 - - - -0.0563 - 3.115 0.493 - 821.4 1 2 0 -0.0001 13 0 0 0 0.00E+00 0.00E+00 - - - 5.5984 0.9969 230117_WJC_METTL3_WT_vs_EV_F05.22054.22054.2 0.186 14-Aug K.GSLLDFLK[136.11].E "sp|P07947|YES_HUMAN,sp|P09769|FGR_HUMAN,sp|P07948|LYN_HUMAN,sp|P08631|HCK_HUMAN,sp|P06241|FYN_HUMAN,sp|P12931|SRC_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|J3QRU1|J3QRU1_HUMAN" 9 899.5208 -1 45066 22054 2 899.522308 450.7677 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 3971.9 - 1.01E+06 - - - 1.7109 - 1.506 0.149 - 201.1 1 2 0 0.0015 8 0 0 0 0.00E+00 0.00E+00 - - - 1.3759 1 230117_WJC_METTL3_WT_vs_EV_F05.22055.22055.2 1.06E-07 22-Dec R.LGDPLEAFPVFK.K "sp|Q86UY6|NAA40_HUMAN,tr|F5H2C9|F5H2C9_HUMAN" 2 1331.7125 1.27 45067 22055 2 1331.715583 666.8635 N-alpha-acetyltransferase 40 OS=Homo sapiens OX=9606 GN=NAA40 PE=1 SV=1 4.37 3972 - 906366 - - - 2.2858 - 2.604 0.533 - 563.7 1 2 0 0.003 12 0 0 0 9.08E+06 7.18E+06 - - - 5.4949 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.22057.22057.2 0.00394 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 45069 22057 2 1603.765232 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3972.2 - 671086 - - - 0.8056 - 1.493 0.424 - 163.7 1 2 0 0.0013 12 0 0 0 3.73E+06 0.00E+00 - - - 3.2268 1 230117_WJC_METTL3_WT_vs_EV_F05.22058.22058.2 7.77E-08 26-Dec K.TFFPEEISSMVLTK.M sp|P54652|HSP72_HUMAN 1 1627.8167 -1 45070 22058 2 1627.817398 814.9156 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.53 3972.3 - 529503 - - - 0.4005 - 2.257 0.548 - 351.1 1 2 0 0.0007 14 0 0 0 0.00E+00 0.00E+00 - - - 5.1311 1 230117_WJC_METTL3_WT_vs_EV_F05.22059.22059.3 4.00E-11 28/80 N.WITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 2344.2539 8.74 45071 22059 3 2344.257858 782.4253 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3972.5 - 519192 - - - 1.6756 - 4.067 0.608 - 692.1 1 1 0 0.0039 21 0 0 0 2.23E+07 2.55E+06 - - - 8.6809 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.22061.22061.3 0.000126 14/52 K.FLTLPPVLHLQLMR[166.11].F "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1686.9883 -1 45072 22061 3 1686.991518 563.3367 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 9.76 3972.7 - 618096 - - - 1.923 - 2.634 0.414 - 208.6 1 2 0 0.0032 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7286 1 230117_WJC_METTL3_WT_vs_EV_F05.22063.22063.2 0.000111 18-Nov K.ILYDILAFAK[136.11].E "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1173.6889 -1 45074 22063 2 1173.695172 587.8517 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.83 3972.8 - 2.82E+06 - - - 5.3464 - 2.268 0.52 - 268.7 1 2 0 0.0063 10 0 0 0 0.00E+00 0.00E+00 - - - 5.1655 1 230117_WJC_METTL3_WT_vs_EV_F05.22070.22070.2 4.41E-06 18-Oct R.DFVVGALILR[166.11].S sp|Q9NUD5|ZCHC3_HUMAN 1 1111.6629 -1 45081 22070 2 1111.663037 556.8387 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 5.84 3973.4 - 1.24E+06 - - - 0.1232 - 1.935 0.515 - 421.5 1 2 0 0.0001 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6873 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22072.22072.2 0.00788 16-Aug K.EVWDYVFFK[136.11].E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PRP1|A0A6I8PRP1_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 1239.6056 -1 45083 22072 2 1239.607634 620.8101 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.37 3973.5 - 1.16E+06 - - - 1.6723 - 1.797 0.444 - 253.2 1 2 0 0.0021 9 0 0 0 0.00E+00 0.00E+00 - - - 4.0154 1 230117_WJC_METTL3_WT_vs_EV_F05.22073.22073.2 1.91E-05 26-Dec K.IFFIDPNERPVTLY.H "sp|O95619|YETS4_HUMAN,tr|F8W1B9|F8W1B9_HUMAN,tr|F8VTR4|F8VTR4_HUMAN" 3 1722.8981 -1 45084 22073 2 1722.903371 862.4563 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 4.37 3973.7 - 1.06E+06 - - - 3.0547 - 2.203 0.536 - 288 1 1 0 0.0053 14 0 0 0 0.00E+00 0.00E+00 - - - 4.9803 0.993 230117_WJC_METTL3_WT_vs_EV_F05.22074.22074.2 0.845 16-Jul K.EVIASIISR[166.11].Y "sp|Q99551|MTEF1_HUMAN,tr|C9JNM8|C9JNM8_HUMAN,tr|B4DPR9|B4DPR9_HUMAN,tr|C9JE25|C9JE25_HUMAN" 4 996.5843 0.001 45085 22074 2 996.585747 499.2994 "Transcription termination factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=MTERF1 PE=1 SV=1" 6.1 3973.8 - 840712 - - - 1.4359 - 1.362 0.126 - 76.3 2 2 0 0.0014 9 0 0 0 0.00E+00 3.12E+06 - - - 0.7305 1 230117_WJC_METTL3_WT_vs_EV_F05.22076.22076.2 1.02E-06 14/22 R.TEDFIIDTLELR[166.11].S sp|Q01780|EXOSX_HUMAN 1 1473.759 -1 45087 22076 2 1473.766245 737.8868 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 3.92 3974 - 688584 - - - 4.8855 - 2.662 0.48 - 926.2 1 2 0 0.0072 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1601 1 230117_WJC_METTL3_WT_vs_EV_F05.22081.22081.2 2.38E-06 13/22 R.LGDPLEAFPVFK[136.11].K "sp|Q86UY6|NAA40_HUMAN,tr|F5H2C9|F5H2C9_HUMAN" 2 1339.7267 1.27 45091 22081 2 1339.723786 670.8706 N-alpha-acetyltransferase 40 OS=Homo sapiens OX=9606 GN=NAA40 PE=1 SV=1 4.37 3974.7 - 1.01E+06 - - - -2.2042 - 2.537 0.555 - 633 1 2 0 -0.003 12 0 0 0 9.08E+06 7.18E+06 - - - 5.5889 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.22086.22086.2 0.0176 18-Sep K.FLLFSSLVTK.E "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V686|A0A7I2V686_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 1153.6747 1.96 45095 22086 2 1153.67467 577.8446 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 8.75 3975.1 - 3.09E+06 - - - -0.0234 - 1.82 0.417 - 187.8 1 2 0 0 10 0 0 0 1.07E+07 5.45E+06 - - - 3.7925 1 230117_WJC_METTL3_WT_vs_EV_F05.22087.22087.3 1.76E-08 20/56 R.TVFRPPLDIYDVLIR.L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0C4DFX0|A0A0C4DFX0_HUMAN" 2 1816.0247 1.06 45096 22087 3 1816.026306 606.3488 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.63 3975.2 - 2.76E+06 - - - 0.881 - 3.151 0.613 - 443.2 1 2 0 0.0016 15 0 0 0 7.26E+06 6.82E+06 - - - 8.3687 1 230117_WJC_METTL3_WT_vs_EV_F05.22090.22090.2 6.68E-05 18-Oct R.DFVVGALILR.S sp|Q9NUD5|ZCHC3_HUMAN 1 1101.6546 -1 45099 22090 2 1101.654298 551.8346 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 5.84 3975.4 - 1.70E+06 - - - -0.3014 - 1.971 0.547 - 438.9 1 2 0 -0.0003 10 0 0 0 0.00E+00 0.00E+00 - - - 4.9751 0.9181 230117_WJC_METTL3_WT_vs_EV_F05.22094.22094.3 0.00491 15/80 N.WITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2354.2622 -1 45103 22094 3 2354.26118 785.7613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3975.8 - 1.14E+06 - - - -0.4333 - 2.531 0.379 - 149.9 1 1 0 -0.001 21 0 0 0 0.00E+00 0.00E+00 - - - 4.9915 0.9958 230117_WJC_METTL3_WT_vs_EV_F05.22097.22097.2 0.502 16-Jul K.IAILGFAFK.K sp|O60701|UGDH_HUMAN 1 978.5902 -1 45106 22097 2 978.589528 490.3024 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 8.75 3976.2 - 904420 - - - -0.7266 - 1.56 0.197 - 85.9 1 2 0 -0.0007 9 0 0 0 0.00E+00 0.00E+00 - - - 1.7823 0.9989 230117_WJC_METTL3_WT_vs_EV_F05.22101.22101.3 0.000336 Jul-44 K.LIQLMEEIMAEK.E "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1446.7462 -1 45110 22101 3 1446.744624 483.256 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.25 3976.7 - 506024 - - - -1.1059 - 1.86 0.332 - 92 1 2 0 -0.0016 12 0 0 0 0.00E+00 0.00E+00 - - - 3.9612 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.22102.22102.2 0.000178 22-Sep K.LVDTAWLEIMTK[136.11].Y sp|Q9UIG0|BAZ1B_HUMAN 1 1426.7621 -1 45111 22102 2 1426.763181 714.3883 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 4.37 3976.8 - 490364 - - - 0.731 - 1.773 0.36 - 204.1 1 2 0 0.001 12 0 0 0 0.00E+00 0.00E+00 - - - 3.2064 1 230117_WJC_METTL3_WT_vs_EV_F05.22104.22104.2 1.53E-07 17/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 5.67 45112 22104 2 1591.944493 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3977.1 - 2.85E+06 - - - -0.3179 - 2.946 0.606 - 664 1 2 0 -0.0005 15 0 0 0 4.10E+07 7.23E+06 - - - 6.1731 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.22105.22105.3 3.19E-06 14/56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 5.97 45113 22105 3 1591.945273 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3977.1 - 1.18E+06 - - - 0.1721 - 2.823 0.332 - 196.7 1 2 0 0.0003 15 0 0 0 1.14E+07 1.92E+06 - - - 4.9494 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.22107.22107.2 0.627 18-Nov R.ILGLLDAYLK[136.11].T sp|P26641|EF1G_HUMAN 1 1125.6889 0.9 45115 22107 2 1125.689975 563.8517 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3977.2 - 1.34E+07 - - - 0.9576 - 2.235 0.339 - 302.4 1 2 0 0.0011 10 0 0 0 5.02E+07 5.56E+07 - - - 3.7894 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22108.22108.2 0.00121 18-Dec R.ILGLLDAYLK.T sp|P26641|EF1G_HUMAN 1 1117.6747 0.9 45116 22108 2 1117.675875 559.8446 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3977.2 - 1.13E+07 - - - 1.054 - 2.523 0.386 - 361.3 1 2 0 0.0012 10 0 0 0 5.02E+07 5.56E+07 - - - 4.4748 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.22110.22110.2 1.3 18-Oct K.NIFAILQSVK[136.11].A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1139.6794 1.9 45118 22110 2 1139.680943 570.847 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3977.4 - 2.68E+06 - - - 1.3583 - 2.049 0.33 - 227 1 2 0 0.0015 10 0 0 0 2.70E+07 1.42E+07 - - - 3.4802 1 230117_WJC_METTL3_WT_vs_EV_F05.22113.22113.2 0.0129 14/28 R.IPGLLSPHPLLQLSY.T "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1646.9396 - 45121 22113 2 1646.943233 824.4771 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.74 3977.6 - 1.31E+06 - - - 2.2187 - 2.914 0.498 - 551.9 1 1 0 0.0037 15 0 0 0 - - - - - 5.3476 1 230117_WJC_METTL3_WT_vs_EV_F05.22115.22115.2 4.93E-07 16/26 K.LLSDFLDSEVSELR.T sp|Q9BPX3|CND3_HUMAN 1 1621.8199 -1 45123 22115 2 1621.822413 811.9172 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 3.92 3977.8 - 1.26E+06 - - - 1.539 - 3.049 0.587 - 1012.8 1 2 0 0.0025 14 0 0 0 0.00E+00 0.00E+00 - - - 6.1734 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.22116.22116.2 0.0029 20-Dec K.TFSFAIPLIER.L sp|Q9BQ39|DDX50_HUMAN 1 1292.7129 -1 45124 22116 2 1292.716916 647.3637 ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1 5.66 3977.8 - 1.24E+06 - - - 3.1275 - 1.776 0.406 - 428.5 1 2 0 0.004 11 0 0 0 0.00E+00 0.00E+00 - - - 3.5922 1 230117_WJC_METTL3_WT_vs_EV_F05.22117.22117.3 2.80E-09 19/44 K.LREC[160.03]LPLIIFLR.N sp|P62701|RS4X_HUMAN 1 1541.9116 0.96 45125 22117 3 1541.912167 514.9778 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3977.9 - 972143 - - - 0.3742 - 3.396 0.569 - 776.5 1 2 1 0.0006 12 0 0 0 3.89E+07 4.06E+07 - - - 8.2725 1 230117_WJC_METTL3_WT_vs_EV_F05.22118.22118.2 0.0102 26-Sep R.GLLEESSFATLFPK[136.11].Y sp|Q13601|KRR1_HUMAN 1 1545.817 0.95 45126 22118 2 1545.817284 773.9158 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3978.1 - 901975 - - - 0.1766 - 2.426 0.505 - 196.3 1 2 0 0.0003 14 0 0 0 7.49E+06 7.89E+06 - - - 4.9948 1 230117_WJC_METTL3_WT_vs_EV_F05.22119.22119.2 8.11E-08 15/26 K.LLSDFLDSEVSELR[166.11].T sp|Q9BPX3|CND3_HUMAN 1 1631.8282 -1 45127 22119 2 1631.830117 816.9214 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 3.92 3978.2 - 884943 - - - 1.1827 - 2.897 0.609 - 702.3 1 2 0 0.0019 14 0 0 0 0.00E+00 0.00E+00 - - - 6.2077 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.22120.22120.3 1.51E-08 15/60 R.IPAEVLILNSIVLPHK.E "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 2 1755.0658 2.99 45128 22120 3 1755.071593 586.0292 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 6.75 3978.3 - 851600 - - - 3.2768 - 2.854 0.482 - 326.3 1 2 0 0.0058 16 0 0 0 3.38E+06 1.13E+06 - - - 6.6031 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.22125.22125.2 4.31E-05 18-Oct K.NIFAILQSVK.A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1131.6652 1.9 45132 22125 2 1131.666091 566.8399 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3978.9 - 1.59E+07 - - - 0.7918 - 1.931 0.327 - 222.2 1 2 0 0.0009 10 0 0 0 2.70E+07 1.42E+07 - - - 3.2927 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22126.22126.3 0.00496 Oct-44 R.LFVWEILHSTIR[166.11].K "sp|Q09161|NCBP1_HUMAN,tr|X6R941|X6R941_HUMAN" 2 1522.8536 1.29 45133 22126 3 1522.854644 508.6251 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 6.75 3979 - 632973 - - - 0.7151 - 2.212 0.316 - 91 1 2 0 0.0011 12 0 0 0 2.26E+06 1.75E+06 - - - 4.2634 0.997 230117_WJC_METTL3_WT_vs_EV_F05.22128.22128.3 2.19E-05 15/44 K.LR[166.11]EC[160.03]LPLIIFLR[166.11].N sp|P62701|RS4X_HUMAN 1 1561.9281 0.96 45135 22128 3 1561.929085 521.65 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3979.1 - 8.62E+06 - - - 0.6114 - 2.949 0.484 - 477.3 1 2 1 0.001 12 0 0 0 3.89E+07 4.06E+07 - - - 6.9335 1 230117_WJC_METTL3_WT_vs_EV_F05.22129.22129.2 8.88E-06 16/22 R.LGPLLDILADSR.H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1281.7293 1.63 45136 22129 2 1281.730114 641.8719 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3979.2 - 4.89E+06 - - - 0.6725 - 2.934 0.582 - 1161.7 1 2 0 0.0009 12 0 0 0 2.90E+07 1.78E+07 - - - 6.1715 1 230117_WJC_METTL3_WT_vs_EV_F05.22130.22130.2 1.78E-08 20/30 K.LPIVNEDDELVAIIAR.T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1778.9778 -1 45137 22130 2 1778.978509 890.4962 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3979.2 - 4.11E+06 - - - 0.3901 - 3.911 0.644 - 1189 1 2 0 0.0007 16 0 0 0 0.00E+00 0.00E+00 - - - 7.1503 1 230117_WJC_METTL3_WT_vs_EV_F05.22131.22131.3 8.23E-07 14/60 K.LPIVNEDDELVAIIAR.T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1778.9778 1.78 45138 22131 3 1778.977881 593.9999 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3979.3 - 4.06E+06 - - - 0.0371 - 2.953 0.51 - 221.5 1 2 0 0.0001 16 0 0 0 9.52E+06 5.35E+06 - - - 7.0044 0.8669 230117_WJC_METTL3_WT_vs_EV_F05.22132.22132.2 0.00529 14-Jul K.KEDLVFIF.W "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 1009.5484 1.26 45139 22132 2 1009.549 505.7815 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.37 3979.3 - 2.89E+06 - - - 0.5606 - 1.289 0.28 - 122 1 1 0 0.0006 8 0 0 0 6.56E+06 5.21E+06 - - - 1.8746 1 230117_WJC_METTL3_WT_vs_EV_F05.22133.22133.2 2.91E-06 22-Dec K.VNFLPEIITLSK.E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1372.7966 -1 45140 22133 2 1372.798836 687.4056 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.97 3979.4 - 2.73E+06 - - - 1.6266 - 2.195 0.56 - 391 1 2 0 0.0022 12 0 0 0 0.00E+00 0.00E+00 - - - 5.245 1 230117_WJC_METTL3_WT_vs_EV_F05.22134.22134.2 4.51E-05 14/24 R.GNSIIMLEALERV.- "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1443.7756 -1 45141 22134 2 1443.776253 722.8951 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3979.4 - 2.49E+06 - - - 0.4869 - 2.777 0.512 - 745.3 1 2 0 0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 5.4438 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22135.22135.2 0.00024 24-Dec K.NPILWNVADVVIK.F "sp|P04844|RPN2_HUMAN,tr|H0Y5M1|H0Y5M1_HUMAN,tr|Q5JYR3|Q5JYR3_HUMAN" 3 1479.8449 -1 45142 22135 2 1479.846247 740.9298 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 5.84 3979.5 - 2.33E+06 - - - 0.8764 - 2.346 0.435 - 322.9 1 2 0 0.0013 13 0 0 0 0.00E+00 0.00E+00 - - - 4.442 1 230117_WJC_METTL3_WT_vs_EV_F05.22137.22137.2 2.24E-11 21/30 K.LPIVNEDDELVAIIAR[166.11].T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1788.9861 -1 45144 22137 2 1788.986277 895.5003 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3979.6 - 2.08E+06 - - - 0.1073 - 3.914 0.684 - 1232.3 1 2 0 0.0002 16 0 0 0 0.00E+00 0.00E+00 - - - 7.4478 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.22138.22138.3 3.59E-06 15/60 K.LPIVNEDDELVAIIAR[166.11].T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1788.9861 1.78 45145 22138 3 1788.98511 597.336 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3979.7 - 2.05E+06 - - - -0.545 - 2.965 0.412 - 288 1 2 0 -0.001 16 0 0 0 9.52E+06 5.35E+06 - - - 5.9219 0.8739 230117_WJC_METTL3_WT_vs_EV_F05.22139.22139.2 0.0288 14-Jun R.EC[160.03]LNLWGY.E sp|Q86U44|MTA70_HUMAN 1 1053.459 - 45146 22139 2 1053.459559 527.7368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3979.8 - 2.01E+06 - - - 0.562 - 1.257 0.298 - 154 1 1 0 0.0006 8 0 0 0 - - - - - 1.9317 1 230117_WJC_METTL3_WT_vs_EV_F05.22140.22140.2 0.000227 22-Oct K.VNFLPEIITLSK[136.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1380.8108 0.86 45147 22140 2 1380.813307 691.4127 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.97 3979.9 - 1.99E+06 - - - 1.8134 - 2.042 0.552 - 264.6 1 2 0 0.0025 12 0 0 0 7.55E+06 8.75E+06 - - - 4.9958 1 230117_WJC_METTL3_WT_vs_EV_F05.22141.22141.2 0.000268 13/24 R.SDFFLEGPFMPPR.M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1538.7228 2.09 45148 22141 2 1538.721253 770.3687 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3979.9 - 1.80E+06 - - - -0.9963 - 2.814 0.526 - 546.1 1 2 0 -0.0015 13 0 0 0 1.07E+07 5.11E+06 - - - 5.5809 1 230117_WJC_METTL3_WT_vs_EV_F05.22148.22148.2 0.000714 14/22 R.LGPLLDILADSR[166.11].H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1291.7375 1.63 45154 22148 2 1291.739577 646.876 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3980.5 - 3.39E+06 - - - 1.5909 - 2.79 0.441 - 749.8 1 2 0 0.0021 12 0 0 0 2.90E+07 1.78E+07 - - - 4.9973 1 230117_WJC_METTL3_WT_vs_EV_F05.22150.22150.2 5.81E-10 17/30 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 -1 45156 22150 2 1751.86852 876.9399 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3980.6 - 1.82E+06 - - - 1.922 - 3.434 0.664 - 730 1 2 0 0.0034 16 0 0 0 0.00E+00 0.00E+00 - - - 6.9774 1 230117_WJC_METTL3_WT_vs_EV_F05.22153.22153.3 2.51E-05 17/60 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 -1 45159 22153 3 1751.868134 584.9623 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3980.9 - 1.09E+06 - - - 1.7016 - 3.192 0.46 - 418.2 1 2 0 0.003 16 0 0 0 0.00E+00 0.00E+00 - - - 6.6458 1 230117_WJC_METTL3_WT_vs_EV_F05.22154.22154.2 7.66E-05 24-Nov R.GNSIIMLEALER[166.11]V.- "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1453.7838 -1 45160 22154 2 1453.787429 727.8992 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3981 - 925683 - - - 2.4825 - 2.564 0.468 - 470.6 1 2 0 0.0036 13 0 0 0 0.00E+00 0.00E+00 - - - 4.9131 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22155.22155.2 8.96E-05 22-Sep R.VLGLLGALDPYK.H sp|P42345|MTOR_HUMAN 1 1257.7333 1.13 45161 22155 2 1257.734392 629.8739 Serine\threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 5.81 3981 - 878609 - - - 0.8881 - 2.096 0.417 - 263.4 1 2 0 0.0011 12 0 0 0 4.05E+06 3.58E+06 - - - 4.0678 0.9969 230117_WJC_METTL3_WT_vs_EV_F05.22157.22157.2 0.000165 16-Oct R.QLYLPMLFK.V "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN" 13 1151.6413 -1 45163 22157 2 1151.637733 576.8279 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3981.2 - 618502 - - - -3.0869 - 1.866 0.438 - 341.5 1 2 0 -0.0036 9 0 0 0 0.00E+00 0.00E+00 - - - 4.0796 0.8937 230117_WJC_METTL3_WT_vs_EV_F05.22159.22159.2 0.822 24-Jun R.EYMSPDIALLYLK.H sp|Q7RTY7|OVCH1_HUMAN 1 1554.8004 10.27 45165 22159 2 1554.807706 778.4075 Ovochymase-1 OS=Homo sapiens OX=9606 GN=OVCH1 PE=2 SV=2 4.37 3981.4 - 477581 - - - 4.7196 - 1.041 0.134 - 70.6 2 2 0 0.0073 13 0 0 0 4.20E+06 4.09E+05 - - - -0.0029 1 230117_WJC_METTL3_WT_vs_EV_F05.22160.22160.2 5.53E-05 13/28 R.SILNADVAELLVVEK.D sp|Q8WVM0|TFB1M_HUMAN 1 1611.9083 -1 45166 22160 2 1611.91475 806.9614 "Dimethyladenosine transferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=TFB1M PE=1 SV=1" 4.14 3981.6 - 470314 - - - 3.9779 - 2.669 0.539 - 422.3 1 2 0 0.0064 15 0 0 0 0.00E+00 0.00E+00 - - - 5.4336 1 230117_WJC_METTL3_WT_vs_EV_F05.22161.22161.3 5.45E-07 17/60 K.VGEVTYVELLMDAEGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1759.8794 -1 45167 22161 3 1759.881947 587.6337 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3981.7 - 456597 - - - 1.474 - 3.174 0.51 - 366.7 1 2 0 0.0026 16 0 0 0 0.00E+00 0.00E+00 - - - 7.1888 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.22162.22162.2 0.000922 28-Nov R.SILNADVAELLVVEK[136.11].D sp|Q8WVM0|TFB1M_HUMAN 1 1619.9225 -1 45168 22162 2 1619.926061 810.9685 "Dimethyladenosine transferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=TFB1M PE=1 SV=1" 4.14 3981.8 - 420556 - - - 2.1748 - 1.698 0.392 - 207.7 1 2 0 0.0035 15 0 0 0 0.00E+00 0.00E+00 - - - 3.2369 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22164.22164.2 0.0635 14/22 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 1 45170 22164 2 1344.864948 673.4385 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3982.1 - 417019 - - - 1.8612 - 2.451 0.375 - 685.5 1 2 0 0.0025 12 0 0 0 1.24E+08 1.23E+08 - - - 4.1688 1 230117_WJC_METTL3_WT_vs_EV_F05.22168.22168.2 1.33E-06 17/32 K.VVLEAPLITESALEVVR.K "sp|Q92797|SYMPK_HUMAN,tr|A0A087WUE9|A0A087WUE9_HUMAN" 2 1837.0561 -1 45173 22168 2 1837.054552 919.5353 Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2 4.25 3982.6 - 426286 - - - -0.8236 - 3.242 0.598 - 675.1 1 2 0 -0.0015 17 0 0 0 0.00E+00 0.00E+00 - - - 6.3491 1 230117_WJC_METTL3_WT_vs_EV_F05.22169.22169.2 6.66E-13 17/30 K.VGEVTYVELLMDAEGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1759.8794 -1 45174 22169 2 1759.879933 880.947 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3982.6 - 5.52E+06 - - - 0.3296 - 3.481 0.62 - 647.3 1 2 0 0.0006 16 0 0 0 0.00E+00 0.00E+00 - - - 6.6867 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22170.22170.2 0.0361 13/22 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 1 45175 22170 2 1336.849854 669.4314 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3982.7 - 4.91E+06 - - - 1.2036 - 2.376 0.38 - 600 1 2 0 0.0016 12 0 0 0 1.24E+08 1.23E+08 - - - 4.1242 1 230117_WJC_METTL3_WT_vs_EV_F05.22171.22171.2 1.78E-05 15/28 K.LGLLGLANSLAIEGR.K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1495.8722 -1 45176 22171 2 1495.874224 748.9434 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3982.7 - 3.98E+06 - - - 1.3343 - 3.012 0.552 - 819.6 1 2 0 0.002 15 0 0 0 0.00E+00 0.00E+00 - - - 5.8282 1 230117_WJC_METTL3_WT_vs_EV_F05.22173.22173.2 4.00E-05 22-Nov R.YLDFSSIITEVR.A sp|Q8N1N4|K2C78_HUMAN 1 1441.7453 -1 45178 22173 2 1441.747915 721.8799 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.37 3982.9 - 2.79E+06 - - - 1.8165 - 2.436 0.575 - 336.4 1 2 0 0.0026 12 0 0 0 0.00E+00 0.00E+00 - - - 5.6298 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.22174.22174.3 1.18E-06 14/52 R.LLNNAFEELVAFQR.A "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1662.873 2.58 45179 22174 3 1662.878077 555.2983 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.53 3982.9 - 2.48E+06 - - - 3.0796 - 2.751 0.54 - 221.7 1 2 0 0.0051 14 0 0 0 1.01E+07 3.90E+06 - - - 7.2484 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.22175.22175.3 0.000126 17/56 K.LGLLGLANSLAIEGR.K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1495.8722 -1 45180 22175 3 1495.874177 499.6314 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3983 - 2.16E+06 - - - 1.3029 - 2.51 0.492 - 335.7 1 2 0 0.0019 15 0 0 0 0.00E+00 0.00E+00 - - - 6.4261 1 230117_WJC_METTL3_WT_vs_EV_F05.22176.22176.2 1.37E-05 14/28 K.LGLLGLANSLAIEGR[166.11].K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1505.8805 -1 45181 22176 2 1505.885859 753.9475 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3983 - 1.95E+06 - - - 3.56 - 3.091 0.557 - 785.8 1 2 0 0.0054 15 0 0 0 0.00E+00 0.00E+00 - - - 5.9278 1 230117_WJC_METTL3_WT_vs_EV_F05.22177.22177.2 2.95E-07 14/20 K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 -1 45182 22177 2 1315.787732 658.9005 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3983.1 - 1.81E+06 - - - 1.0328 - 2.565 0.579 - 720.3 1 2 0 0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 5.8653 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22179.22179.2 5.54E-05 18-Oct K.VLVYELLLGK.G sp|Q96P11|NSUN5_HUMAN 1 1145.706 1.33 45184 22179 2 1145.707224 573.8603 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 5.97 3983.3 - 1.67E+06 - - - 1.071 - 1.96 0.419 - 292.2 1 2 0 0.0012 10 0 0 0 4.19E+06 3.14E+06 - - - 4.0137 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.22180.22180.2 0.000689 18-Aug K.VLVYELLLGK[136.11].G sp|Q96P11|NSUN5_HUMAN 1 1153.7202 -1 45185 22180 2 1153.723138 577.8674 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 5.97 3983.3 - 1.56E+06 - - - 2.5491 - 1.691 0.405 - 137.9 1 2 0 0.0029 10 0 0 0 0.00E+00 0.00E+00 - - - 3.4977 1 230117_WJC_METTL3_WT_vs_EV_F05.22181.22181.2 0.00103 14/26 R.ALVENC[160.03]LVPDLWIR.Y "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 1696.8971 -1 45186 22181 2 1696.895636 849.4558 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.37 3983.5 - 1.49E+06 - - - -0.8409 - 2.456 0.464 - 667.5 1 2 0 -0.0014 14 0 0 0 0.00E+00 0.00E+00 - - - 4.7225 1 230117_WJC_METTL3_WT_vs_EV_F05.22182.22182.2 7.83E-09 16/26 R.LLNNAFEELVAFQR.A "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1662.873 2.61 45187 22182 2 1662.876664 832.4438 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.53 3983.6 - 1.48E+06 - - - 2.2299 - 3.172 0.633 - 1137.4 1 2 0 0.0037 14 0 0 0 6.50E+06 2.49E+06 - - - 6.612 0.995 230117_WJC_METTL3_WT_vs_EV_F05.22183.22183.2 0.0505 20-Jun R.FLIPVLNGLEK.K "sp|Q92797|SYMPK_HUMAN,tr|A0A087WUE9|A0A087WUE9_HUMAN" 2 1241.7384 -1 45188 22183 2 1241.739216 621.8765 Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2 6 3983.6 - 1.34E+06 - - - 0.6894 - 1.376 0.173 - 79.8 2 2 0 0.0009 11 0 0 0 0.00E+00 0.00E+00 - - - 1.0475 1 230117_WJC_METTL3_WT_vs_EV_F05.22185.22185.2 3.41E-05 20-Dec K.EYPFILDAFQR[166.11].E sp|P42285|MTREX_HUMAN 1 1407.7062 1.04 45190 22185 2 1407.708544 704.8604 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 3983.9 - 1.07E+06 - - - 1.6495 - 2.212 0.521 - 611.8 1 2 0 0.0023 11 0 0 0 6.28E+06 6.04E+06 - - - 5.0361 1 230117_WJC_METTL3_WT_vs_EV_F05.22188.22188.2 0.000176 13/18 K.LASDLLEWIR.R "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|G3V2W4|G3V2W4_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 14 1214.6659 -1 45192 22188 2 1214.667512 608.3402 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.37 3984.3 - 1.38E+06 - - - 1.3082 - 2.519 0.425 - 615.3 1 2 0 0.0016 10 0 0 0 0.00E+00 0.00E+00 - - - 4.7583 1 230117_WJC_METTL3_WT_vs_EV_F05.22192.22192.2 5.70E-05 20-Dec K.TLSYLLPLLQR[166.11].L sp|Q9NUL7|DDX28_HUMAN 1 1325.7946 1.06 45196 22192 2 1325.79648 663.9046 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3984.5 - 6.83E+06 - - - 1.3856 - 1.967 0.514 - 481 1 2 0 0.0018 11 0 0 0 1.66E+07 1.56E+07 - - - 4.6669 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22194.22194.2 9.77E-06 20-Sep K.EYPFILDAFQR.E sp|P42285|MTREX_HUMAN 1 1397.698 1.04 45198 22194 2 1397.698479 699.8563 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 3984.6 - 2.53E+06 - - - 0.377 - 1.904 0.47 - 282.2 1 2 0 0.0005 11 0 0 0 6.28E+06 6.04E+06 - - - 4.2543 1 230117_WJC_METTL3_WT_vs_EV_F05.22195.22195.2 0.000209 18-Nov K.LNMILVQILK.Q "sp|O14980|XPO1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 1183.7363 -1 45199 22195 2 1183.736857 592.8754 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3984.7 - 2.45E+06 - - - 0.5119 - 2.449 0.416 - 407.7 1 2 0 0.0006 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6135 1 230117_WJC_METTL3_WT_vs_EV_F05.22196.22196.3 0.000142 16/44 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 0.98 45200 22196 3 1336.848154 446.6234 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3984.7 - 2.21E+06 - - - -0.0681 - 2.767 0.53 - 350.2 1 2 0 -0.0001 12 0 0 0 8.69E+06 8.87E+06 - - - 7.27 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.22197.22197.3 9.52E-06 13/44 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 0.98 45201 22197 3 1344.862578 449.2948 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3984.8 - 2.12E+06 - - - 0.0989 - 2.252 0.451 - 234.8 1 2 0 0.0001 12 0 0 0 8.69E+06 8.87E+06 - - - 5.8184 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.22198.22198.2 0.000391 18-Dec K.LNMILVQILK[136.11].Q "sp|O14980|XPO1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 1191.7505 -1 45202 22198 2 1191.750536 596.8825 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3984.9 - 1.83E+06 - - - 0.0713 - 2.327 0.417 - 460.6 1 2 0 0.0001 10 0 0 0 0.00E+00 0.00E+00 - - - 4.4784 1 230117_WJC_METTL3_WT_vs_EV_F05.22199.22199.2 2.40E-15 23/38 K.MLLDPMGGIVMTNDGNAILR.E "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 2130.0636 -1 45203 22199 2 2130.065497 1066.0391 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.21 3985 - 1.78E+06 - - - 0.9131 - 3.837 0.723 - 1563 1 2 0 0.0019 20 0 0 0 0.00E+00 0.00E+00 - - - 7.6865 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22201.22201.2 4.22E-07 18-Dec R.SPNDLLALFR.Y "sp|Q92626|PXDN_HUMAN,tr|H7C1W1|H7C1W1_HUMAN" 2 1144.6241 0.17 45205 22201 2 1144.626004 573.3193 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 5.55 3985.1 - 1.53E+06 - - - 1.7001 - 2.343 0.423 - 664.9 1 2 0 0.0019 10 0 0 0 4.58E+06 2.68E+07 - - - 4.5413 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.22202.22202.3 0.00702 Dec-40 K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 1.12 45206 22202 3 1315.786656 439.6027 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3985.2 - 1.46E+06 - - - 0.2151 - 2.276 0.384 - 280.8 1 2 0 0.0003 11 0 0 0 3.13E+06 2.80E+06 - - - 5.1575 1 230117_WJC_METTL3_WT_vs_EV_F05.22203.22203.2 6.56E-06 26-Oct K.ELAEEGVLEEAEFY.N sp|Q14681|KCTD2_HUMAN 1 1626.7301 - 45207 22203 2 1626.73058 814.3723 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 3.46 3985.3 - 1.29E+06 - - - 0.2957 - 2.269 0.586 - 165.2 1 1 0 0.0005 14 0 0 0 - - - - - 5.4251 0.9972 230117_WJC_METTL3_WT_vs_EV_F05.22204.22204.2 0.016 18-Aug K.GGPGLPLPPL.- sp|Q9H7N4|SFR19_HUMAN 1 916.5382 - 45208 22204 2 916.53763 459.2764 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.52 3985.4 - 1.21E+06 - - - -0.6252 - 1.289 0.318 - 215.1 1 2 0 -0.0006 10 0 0 0 - - - - - 2.0982 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.22205.22205.3 0.00189 15/60 R.FLLPEYLPYAGIFHER.G "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1964.0196 -1 45209 22205 3 1964.02052 655.6805 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 5.4 3985.5 - 1.13E+06 - - - 0.4582 - 2.633 0.438 - 258.9 1 2 0 0.0009 16 0 0 0 0.00E+00 0.00E+00 - - - 5.9071 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.22206.22206.3 0.00392 Nov-40 K.TLSYLLPLLQR[166.11].L sp|Q9NUL7|DDX28_HUMAN 1 1325.7946 -1 45210 22206 3 1325.794279 442.9388 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3985.6 - 1.03E+06 - - - -0.2746 - 2.001 0.296 - 189.9 1 2 0 -0.0004 11 0 0 0 0.00E+00 0.00E+00 - - - 3.8105 1 230117_WJC_METTL3_WT_vs_EV_F05.22212.22212.3 1.58E-11 21/76 K.MLLDPMGGIVMTNDGNAILR.E "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 2130.0636 -1 45215 22212 3 2130.062727 711.0285 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.21 3986.1 - 5.01E+06 - - - -0.3873 - 3.708 0.649 - 548 1 2 0 -0.0008 20 0 0 0 0.00E+00 0.00E+00 - - - 8.9548 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.22215.22215.2 0.0137 22-Nov R.NLQNLLILTAIK[136.11].A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1360.8533 1.01 45218 22215 2 1360.852772 681.4339 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3986.4 - 1.64E+06 - - - -0.4152 - 1.979 0.347 - 293.7 1 2 0 -0.0006 12 0 0 0 2.39E+07 2.38E+07 - - - 3.3998 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22216.22216.2 0.000208 18-Oct K.FDTIYQILLK.K "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 1252.7067 -1 45219 22216 2 1252.70795 627.3606 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 5.83 3986.5 - 1.37E+06 - - - 0.9779 - 2.101 0.41 - 310.9 1 2 0 0.0012 10 0 0 0 0.00E+00 0.00E+00 - - - 4.1412 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22217.22217.2 0.000313 14-Aug R.LLFFWSDR.R "sp|Q9H6Z9|EGLN3_HUMAN,sp|Q9GZT9|EGLN1_HUMAN,tr|G3V3M1|G3V3M1_HUMAN,tr|F8W1G2|F8W1G2_HUMAN,tr|A0A590UJT7|A0A590UJT7_HUMAN,tr|A0A590UJ78|A0A590UJ78_HUMAN,tr|A0A590UJK7|A0A590UJK7_HUMAN" 7 1082.5549 -1 45220 22217 2 1082.555917 542.2847 Prolyl hydroxylase EGLN3 OS=Homo sapiens OX=9606 GN=EGLN3 PE=1 SV=1 5.84 3986.6 - 1.34E+06 - - - 0.9247 - 1.748 0.469 - 232.1 1 2 0 0.001 8 0 0 0 0.00E+00 0.00E+00 - - - 4.189 1 230117_WJC_METTL3_WT_vs_EV_F05.22227.22227.2 6.72E-08 16/28 K.GVFVQSVLPYFVATK.L "sp|Q53GQ0|DHB12_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN" 2 1653.913 -1 45230 22227 2 1653.917421 827.9638 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 8.59 3987.8 - 492167 - - - 2.6549 - 2.714 0.586 - 635 1 2 0 0.0044 15 0 0 0 0.00E+00 0.00E+00 - - - 5.8225 1 230117_WJC_METTL3_WT_vs_EV_F05.22228.22228.2 6.00E-06 14/26 R.ISLPLPNFSSLNLR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1569.8879 1.56 45231 22228 2 1569.885317 785.9512 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3987.9 - 490806 - - - -1.6313 - 2.58 0.591 - 496.9 1 2 0 -0.0026 14 0 0 0 8.86E+06 5.68E+06 - - - 5.7838 1 230117_WJC_METTL3_WT_vs_EV_F05.22231.22231.2 8.66E-07 14/22 R.NLQNLLILTAIK.A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1352.8391 1.01 45233 22231 2 1352.838933 677.4268 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3988.3 - 1.18E+07 - - - -0.1508 - 2.636 0.612 - 627.3 1 2 0 -0.0002 12 0 0 0 2.39E+07 2.38E+07 - - - 6.1115 0.8986 230117_WJC_METTL3_WT_vs_EV_F05.22232.22232.2 0.0135 18-Jun E.QEEDISSLIR.S sp|P78527|PRKDC_HUMAN 1 1188.5986 8.28 45234 22232 2 1188.599283 595.3066 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.14 3988.4 - 1.15E+07 - - - 0.5477 - 1.377 0.303 - 100.2 1 1 0 0.0007 10 0 0 0 2.73E+07 3.29E+06 - - - 2.1717 1 230117_WJC_METTL3_WT_vs_EV_F05.22233.22233.2 7.61E-07 18/28 R.LPFLSSSNLSLDVLR.G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1659.9196 -1 45235 22233 2 1659.919792 830.9671 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3988.4 - 6.44E+06 - - - 0.1325 - 3.548 0.588 - 1185.6 1 2 0 0.0002 15 0 0 0 0.00E+00 0.00E+00 - - - 6.4974 1 230117_WJC_METTL3_WT_vs_EV_F05.22234.22234.2 1.09E-10 18/28 R.LPFLSSSNLSLDVLR[166.11].G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1669.9278 -1 45236 22234 2 1669.92771 835.9712 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3988.5 - 5.35E+06 - - - -0.079 - 3.517 0.624 - 1139.5 1 2 0 -0.0001 15 0 0 0 0.00E+00 0.00E+00 - - - 6.7417 1 230117_WJC_METTL3_WT_vs_EV_F05.22236.22236.2 2.83E-10 19/32 R.AFLQGGQEATDIALLLR.D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1814.989 -1 45238 22236 2 1814.989756 908.5018 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3988.6 - 3.89E+06 - - - 0.3901 - 3.743 0.674 - 1198.1 1 2 0 0.0007 17 0 0 0 0.00E+00 0.00E+00 - - - 7.2639 1 230117_WJC_METTL3_WT_vs_EV_F05.22238.22238.3 4.85E-08 14/52 R.HPYFYAPELLFFAK.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 1741.8868 45 45240 22238 3 1741.887437 581.6362 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6.75 3988.7 - 1.70E+06 - - - 0.3571 - 2.804 0.588 - 328.1 1 2 0 0.0006 14 0 0 0 3.87E+06 8.59E+04 - - - 7.8355 1 230117_WJC_METTL3_WT_vs_EV_F05.22239.22239.2 1.97E-10 18/32 R.AFLQGGQEATDIALLLR[166.11].D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1824.9973 -1 45241 22239 2 1824.994682 913.5059 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3988.8 - 1.69E+06 - - - -1.4444 - 3.415 0.694 - 992.8 1 2 0 -0.0026 17 0 0 0 0.00E+00 0.00E+00 - - - 7.1856 1 230117_WJC_METTL3_WT_vs_EV_F05.22240.22240.2 5.96E-10 13/28 K.LTILQSLGDPLYYGK.L "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 1679.9134 -1 45242 22240 2 1679.914664 840.964 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.83 3988.9 - 1.55E+06 - - - 0.7381 - 2.673 0.54 - 530.5 1 2 0 0.0012 15 0 0 0 0.00E+00 0.00E+00 - - - 5.4463 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.22243.22243.3 9.24E-06 Dec-44 R.NLQNLLILTAIK.A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1352.8391 -1 45245 22243 3 1352.838405 451.9537 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3989.2 - 1.38E+06 - - - -0.5411 - 2.611 0.453 - 366.5 1 2 0 -0.0007 12 0 0 0 0.00E+00 0.00E+00 - - - 6.2505 1 230117_WJC_METTL3_WT_vs_EV_F05.22244.22244.2 0.00184 20-Dec R.FILNLPTFSVR.L "sp|P49721|PSB2_HUMAN,tr|A0A087WVV1|A0A087WVV1_HUMAN" 2 1305.7445 -1 45246 22244 2 1305.744492 653.8795 Proteasome subunit beta type-2 OS=Homo sapiens OX=9606 GN=PSMB2 PE=1 SV=1 9.75 3989.3 - 1.38E+06 - - - -0.0123 - 2.338 0.444 - 387.2 1 2 0 0 11 0 0 0 0.00E+00 0.00E+00 - - - 4.6179 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.22246.22246.2 6.11E-05 13/24 K.GNLEVLLFTIQSK.L "sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 5 1460.8239 -1 45248 22246 2 1460.825564 731.4192 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6 3989.5 - 1.14E+06 - - - 1.1521 - 2.209 0.357 - 511.3 1 2 0 0.0017 13 0 0 0 0.00E+00 0.00E+00 - - - 3.7114 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.22247.22247.2 0.00983 13/24 K.GNLEVLLFTIQSK[136.11].L "sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 5 1468.8381 -1 45249 22247 2 1468.840766 735.4263 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6 3989.6 - 1.10E+06 - - - 1.828 - 2.219 0.381 - 607.6 1 2 0 0.0027 13 0 0 0 0.00E+00 0.00E+00 - - - 3.8999 0.9993 230117_WJC_METTL3_WT_vs_EV_F05.22249.22249.3 0.00616 Oct-44 R.NLQNLLILTAIK[136.11].A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1360.8533 -1 45251 22249 3 1360.853739 454.6251 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3989.8 - 838895 - - - 0.2954 - 2.376 0.235 - 237 1 2 0 0.0004 12 0 0 0 0.00E+00 0.00E+00 - - - 3.5587 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.22251.22251.2 0.00316 22-Aug K.NVLITDFFGSVR.K "sp|Q92643|GPI8_HUMAN,tr|B1AK81|B1AK81_HUMAN,tr|A6NEM5|A6NEM5_HUMAN" 3 1366.7245 -1 45252 22251 2 1366.725363 684.3695 GPI-anchor transamidase OS=Homo sapiens OX=9606 GN=PIGK PE=1 SV=2 5.84 3990 - 1.26E+06 - - - 0.6307 - 1.673 0.36 - 149.5 1 2 0 0.0009 12 0 0 0 0.00E+00 0.00E+00 - - - 3.0537 1 230117_WJC_METTL3_WT_vs_EV_F05.22253.22253.2 0.000104 26-Dec R.VISGVLQLGNIVFK[136.11].K sp|P35579|MYH9_HUMAN 1 1493.9061 -1 45254 22253 2 1493.907234 747.9603 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.72 3990.2 - 4.94E+06 - - - 0.7584 - 2.647 0.604 - 322.4 1 2 0 0.0011 14 0 0 0 0.00E+00 0.00E+00 - - - 5.9446 0.9429 230117_WJC_METTL3_WT_vs_EV_F05.22254.22254.2 0.0183 18-Jun K.VEDLTFTSPF.C "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1154.5496 - 45255 22254 2 1154.550897 578.2821 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 3.67 3990.2 - 4.15E+06 - - - 1.1615 - 1.307 0.393 - 100.6 1 1 0 0.0013 10 0 0 0 - - - - - 2.6906 1 230117_WJC_METTL3_WT_vs_EV_F05.22259.22259.2 0.000104 13/24 R.AIAYLFPSGLFEK[136.11].R sp|P82933|RT09_HUMAN 1 1462.7952 1.12 45260 22259 2 1462.798695 732.4049 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 6.05 3990.5 - 1.88E+06 - - - 2.4214 - 2.863 0.423 - 558.9 1 2 0 0.0035 13 0 0 0 1.30E+07 1.16E+07 - - - 4.8638 1 230117_WJC_METTL3_WT_vs_EV_F05.22260.22260.2 0.00585 20-Dec K.FVDILTNWYVR.M "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1424.7452 -1 45261 22260 2 1424.746832 713.3799 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.84 3990.5 - 1.87E+06 - - - 1.1202 - 2.567 0.541 - 560.4 1 2 0 0.0016 11 0 0 0 0.00E+00 0.00E+00 - - - 5.5867 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22261.22261.2 1.04E-07 22-Dec R.SQALIEELLLYK.R sp|Q5VT52|RPRD2_HUMAN 1 1418.8021 -1 45262 22261 2 1418.804325 710.4083 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3990.6 - 1.87E+06 - - - 1.5809 - 2.398 0.407 - 263 1 2 0 0.0022 12 0 0 0 0.00E+00 0.00E+00 - - - 4.3477 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22264.22264.2 0.000669 14/20 R.VLDLVEVLVTK.Q "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1226.7486 -1 45265 22264 2 1226.749824 614.3816 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.37 3990.8 - 1.68E+06 - - - 1.0059 - 1.622 0.496 - 307.7 1 2 0 0.0012 11 0 0 0 0.00E+00 0.00E+00 - - - 4.0125 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.22265.22265.3 0.0237 Sep-48 R.GNTAAYLLYAFTR.L sp|P54136|SYRC_HUMAN 1 1459.746 -1 45266 22265 3 1459.747518 487.5893 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.59 3990.9 - 1.61E+06 - - - 1.0639 - 1.832 0.396 - 99.2 1 2 0 0.0016 13 0 0 0 0.00E+00 0.00E+00 - - - 4.596 1 230117_WJC_METTL3_WT_vs_EV_F05.22266.22266.2 3.49E-09 14/32 K.LFEMVLGPAAYNVPLPK.K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1858.0063 2.22 45267 22266 2 1858.012345 930.0104 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6 3991 - 1.49E+06 - - - 3.2653 - 2.928 0.567 - 621.7 1 2 0 0.0061 17 0 0 0 4.13E+06 1.86E+06 - - - 5.8682 1 230117_WJC_METTL3_WT_vs_EV_F05.22267.22267.2 6.93E-08 15/24 R.DPTYFGPVLNYLR[166.11].H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1563.7961 0.85 45268 22267 2 1563.801657 782.9053 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3991 - 1.47E+06 - - - 3.5542 - 2.843 0.661 - 817.3 1 2 0 0.0056 13 0 0 0 7.16E+06 8.41E+06 - - - 6.6031 1 230117_WJC_METTL3_WT_vs_EV_F05.22268.22268.2 1.56E-06 14/22 K.FFDDPMLLELAK.Q "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1437.7214 1.72 45269 22268 2 1437.720718 719.868 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.03 3991.1 - 1.39E+06 - - - -0.4667 - 2.747 0.595 - 297 1 2 0 -0.0007 12 0 0 0 1.37E+07 7.96E+06 - - - 6.0943 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22269.22269.2 0.000277 13/26 R.ISLPLPNFSSLNLR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1579.8961 1.56 45270 22269 2 1579.897907 790.9554 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3991.2 - 1.33E+06 - - - 1.1134 - 2.015 0.434 - 452.7 1 2 0 0.0018 14 0 0 0 8.86E+06 5.68E+06 - - - 4.0041 0.9122 230117_WJC_METTL3_WT_vs_EV_F05.22270.22270.2 2.57 18-Apr R.C[160.03]FSTTLLYC[160.03]R.K sp|P60893|GPR85_HUMAN 1 1319.6002 -1 45271 22270 2 1319.59886 660.8074 Probable G-protein coupled receptor 85 OS=Homo sapiens OX=9606 GN=GPR85 PE=1 SV=1 8.06 3991.3 - 1.27E+06 - - - -1.0374 - 1.062 0.098 - 42.6 4 2 0 -0.0014 10 0 0 0 0.00E+00 0.00E+00 - - - -0.3366 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.22272.22272.2 0.00385 22-Dec R.SLLEPFVYLASK.M "sp|Q9NYR9|KBRS2_HUMAN,tr|K7ERG2|K7ERG2_HUMAN,tr|H7BXP1|H7BXP1_HUMAN" 3 1365.7544 4.38 45272 22272 2 1365.757552 683.8845 NF-kappa-B inhibitor-interacting Ras-like protein 2 OS=Homo sapiens OX=9606 GN=NKIRAS2 PE=1 SV=1 5.72 3991.5 - 2.95E+06 - - - 2.305 - 2.259 0.403 - 436.2 1 2 0 0.0031 12 0 0 0 6.14E+06 1.40E+06 - - - 4.1608 1 230117_WJC_METTL3_WT_vs_EV_F05.22274.22274.2 4.19E-13 18/26 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 8.64 45274 22274 2 1537.77057 769.8922 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3991.6 - 1.79E+07 - - - 0.5033 - 3.292 0.715 - 1064.2 1 2 0 0.0008 14 0 0 0 9.86E+07 1.14E+07 - - - 7.3117 1 230117_WJC_METTL3_WT_vs_EV_F05.22281.22281.3 8.77E-07 14/52 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 12.35 45281 22281 3 1537.771297 513.5972 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3992 - 2.70E+06 - - - 0.9761 - 2.831 0.536 - 355.3 1 2 0 0.0015 14 0 0 0 1.13E+07 9.19E+05 - - - 7.281 1 230117_WJC_METTL3_WT_vs_EV_F05.22282.22282.2 0.000585 15/28 R.ATSFLLALEPELEAR.L "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1658.8879 -1 45282 22282 2 1658.886131 830.4512 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.25 3992.1 - 2.61E+06 - - - -1.0887 - 3.088 0.599 - 682.6 1 2 0 -0.0018 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2367 1 230117_WJC_METTL3_WT_vs_EV_F05.22284.22284.2 6.23E-05 15/28 R.ATSFLLALEPELEAR[166.11].L "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1668.8962 -1 45284 22284 2 1668.899026 835.4554 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.25 3992.2 - 2.00E+06 - - - 1.6891 - 3.084 0.54 - 761.6 1 2 0 0.0028 15 0 0 0 0.00E+00 0.00E+00 - - - 5.7974 0.9991 230117_WJC_METTL3_WT_vs_EV_F05.22285.22285.2 0.00954 20-Aug R.VLDLVEVLVTK[136.11].Q "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1234.7628 -1 45285 22285 2 1234.764737 618.3887 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.37 3992.3 - 1.86E+06 - - - 1.5768 - 1.427 0.344 - 122.6 1 2 0 0.0019 11 0 0 0 0.00E+00 0.00E+00 - - - 2.5431 1 230117_WJC_METTL3_WT_vs_EV_F05.22286.22286.3 8.14E-05 17/56 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 2.02 45286 22286 3 1519.910379 507.6435 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3992.3 - 1.80E+06 - - - 1.1619 - 2.877 0.543 - 364.5 1 2 0 0.0018 15 0 0 0 1.22E+07 6.04E+06 - - - 7.3509 1 230117_WJC_METTL3_WT_vs_EV_F05.22287.22287.3 1.48E-06 19/60 K.IFEIFGPVAHPFYVLR.F sp|Q96HR8|NAF1_HUMAN 1 1904.0349 -1 45287 22287 3 1904.038707 635.6856 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 6.75 3992.4 - 1.66E+06 - - - 2.012 - 3.138 0.489 - 484.7 1 2 0 0.0038 16 0 0 0 0.00E+00 0.00E+00 - - - 6.9251 0.9994 230117_WJC_METTL3_WT_vs_EV_F05.22288.22288.3 0.00558 13/72 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 45288 22288 3 1911.184385 638.0676 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3992.5 - 1.62E+06 - - - 1.8381 - 1.666 0.337 - 100.7 1 2 0 0.0035 19 0 0 0 0.00E+00 0.00E+00 - - - 3.5503 1 230117_WJC_METTL3_WT_vs_EV_F05.22289.22289.2 9.21E-06 24-Dec R.DPTYFGPVLNYLR.H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1553.7878 0.78 45289 22289 2 1553.788027 777.9012 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3992.6 - 1.61E+06 - - - 0.1274 - 2.423 0.501 - 489.6 1 2 0 0.0002 13 0 0 0 6.54E+06 8.41E+06 - - - 5.0127 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22291.22291.2 0.033 14/36 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 45291 22291 2 1911.18348 956.5977 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3992.8 - 1.25E+06 - - - 1.3646 - 2.23 0.432 - 331 1 2 0 0.0026 19 0 0 0 0.00E+00 0.00E+00 - - - 4.2027 1 230117_WJC_METTL3_WT_vs_EV_F05.22299.22299.2 3.62E-06 22-Dec K.AYVVLGQFLVLK[136.11].K sp|O75531|BAF_HUMAN 1 1356.8261 -1 45298 22299 2 1356.827369 679.4203 Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1 8.63 3993.6 - 1.68E+06 - - - 0.9655 - 2.437 0.552 - 447.3 1 2 0 0.0013 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4614 1 230117_WJC_METTL3_WT_vs_EV_F05.22300.22300.2 3.48E-06 19/28 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 2.29 45299 22300 2 1519.909593 760.9616 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3993.7 - 1.59E+06 - - - 0.6448 - 3.193 0.605 - 1517.3 1 2 0 0.001 15 0 0 0 7.60E+06 3.32E+06 - - - 6.3635 1 230117_WJC_METTL3_WT_vs_EV_F05.22302.22302.3 4.40E-05 16/56 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 2.02 45301 22302 3 1529.918226 510.9796 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3993.9 - 1.33E+06 - - - 0.8778 - 2.686 0.481 - 316.6 1 2 0 0.0013 15 0 0 0 1.22E+07 6.04E+06 - - - 6.4805 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22303.22303.2 8.95E-05 22-Sep K.AYVVLGQFLVLK.K sp|O75531|BAF_HUMAN 1 1348.8119 -1 45302 22303 2 1348.813532 675.4132 Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1 8.63 3994 - 1.13E+06 - - - 1.2404 - 2.049 0.484 - 250.2 1 2 0 0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 4.5028 0.9737 230117_WJC_METTL3_WT_vs_EV_F05.22305.22305.2 5.11E-05 22-Aug K.NTPFLYDLVMTH.A "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|E9PIC4|E9PIC4_HUMAN,tr|E9PNS2|E9PNS2_HUMAN,tr|E9PNS6|E9PNS6_HUMAN,tr|C9JAJ9|C9JAJ9_HUMAN,tr|E9PC52|E9PC52_HUMAN" 7 1449.6962 - 45304 22305 2 1449.697747 725.8554 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.08 3994.2 - 937500 - - - 1.0416 - 1.674 0.473 - 137.8 1 1 0 0.0015 12 0 0 0 - - - - - 3.8897 1 230117_WJC_METTL3_WT_vs_EV_F05.22306.22306.3 2.35E-07 19/72 R.LPVVIGGLLDVDC[160.03]SEDVIK[136.11].N "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2048.0955 -1 45305 22306 3 2048.097187 683.7058 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 3.84 3994.3 - 911515 - - - 0.8266 - 2.923 0.55 - 321.2 1 2 0 0.0017 19 0 0 0 0.00E+00 0.00E+00 - - - 7.3067 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.22309.22309.3 0.00046 Oct-44 K.AILC[160.03]LLLGGVER.D "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1312.7537 -1 45308 22309 3 1312.752018 438.5918 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 6.04 3994.6 - 696935 - - - -1.2759 - 1.895 0.399 - 173.1 1 2 0 -0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 4.7598 1 230117_WJC_METTL3_WT_vs_EV_F05.22310.22310.2 4.85E-08 18/28 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 -1 45309 22310 2 1529.919489 765.9657 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3994.8 - 678726 - - - 1.7034 - 3.067 0.6 - 995.4 1 2 0 0.0026 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2271 1 230117_WJC_METTL3_WT_vs_EV_F05.22315.22315.2 0.000117 13/22 K.AILC[160.03]LLLGGVER.D "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1312.7537 -1 45313 22315 2 1312.755329 657.3841 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 6.04 3995.3 - 668773 - - - 1.2462 - 2.597 0.443 - 852.2 1 2 0 0.0016 12 0 0 0 0.00E+00 0.00E+00 - - - 4.8236 1 230117_WJC_METTL3_WT_vs_EV_F05.22316.22316.2 1.67E-07 18-Nov R.C[160.03]WAGSLWLFK[136.11].D sp|Q9BQA1|MEP50_HUMAN 1 1274.6362 0.47 45314 22316 2 1274.638011 638.3254 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 3995.3 - 2.88E+07 - - - 1.46 - 2.125 0.569 - 396.5 1 2 0 0.0019 10 0 0 0 2.46E+07 5.24E+07 - - - 5.3471 0.9992 230117_WJC_METTL3_WT_vs_EV_F05.22317.22317.2 0.0134 16-Sep K.LLLPWLEAR.L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1109.6597 -1 45315 22317 2 1109.6615 555.8371 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6 3995.4 - 1.70E+07 - - - 1.6077 - 1.702 0.273 - 355.3 1 2 0 0.0018 9 0 0 0 0.00E+00 0.00E+00 - - - 2.5954 1 230117_WJC_METTL3_WT_vs_EV_F05.22318.22318.2 2.57E-08 18-Nov R.C[160.03]WAGSLWLFK.D sp|Q9BQA1|MEP50_HUMAN 1 1266.6219 0.47 45316 22318 2 1266.62416 634.3183 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 3995.4 - 1.27E+07 - - - 1.7448 - 2.26 0.625 - 340.3 1 2 0 0.0022 10 0 0 0 2.46E+07 5.24E+07 - - - 5.9325 1 230117_WJC_METTL3_WT_vs_EV_F05.22320.22320.3 1.44E-05 14/44 K.FFEVILIDPFHK[136.11].A "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 4 1511.8268 -1 45318 22320 3 1511.827674 504.9495 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 5.32 3995.5 - 4.15E+06 - - - 0.586 - 2.463 0.559 - 219.3 1 2 0 0.0009 12 0 0 0 0.00E+00 0.00E+00 - - - 7.2705 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.22322.22322.2 0.0383 18-Nov R.AALLELWELR[166.11].R "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1222.6949 -1 45320 22322 2 1222.697721 612.3547 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 3995.6 - 3.16E+06 - - - 2.2835 - 2.653 0.337 - 442.7 1 2 0 0.0028 10 0 0 0 0.00E+00 0.00E+00 - - - 4.2527 1 230117_WJC_METTL3_WT_vs_EV_F05.22323.22323.3 8.60E-07 15/44 K.FFEVILIDPFHK.A "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 4 1503.8126 0.81 45321 22323 3 1503.81459 502.2781 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 5.32 3995.7 - 3.13E+06 - - - 1.3313 - 2.568 0.523 - 238.3 1 2 0 0.002 12 0 0 0 1.12E+07 1.38E+07 - - - 6.9846 1 230117_WJC_METTL3_WT_vs_EV_F05.22324.22324.2 1.46E-09 16/30 K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 -1 45322 22324 2 1701.890311 851.9512 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3995.7 - 2.51E+06 - - - 1.4296 - 2.812 0.566 - 629.2 1 2 0 0.0024 16 0 0 0 0.00E+00 0.00E+00 - - - 5.7626 1 230117_WJC_METTL3_WT_vs_EV_F05.22325.22325.2 1.36E-05 15/30 K.AAGVNVEPFWPGLFAK[136.11].A sp|P05386|RLA1_HUMAN 1 1709.9021 -1 45323 22325 2 1709.905006 855.9583 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3995.8 - 1.65E+06 - - - 1.7124 - 3.022 0.547 - 550.5 1 2 0 0.0029 16 0 0 0 0.00E+00 0.00E+00 - - - 5.7992 1 230117_WJC_METTL3_WT_vs_EV_F05.22326.22326.2 1.29E-07 24-Oct K.LVDQNIFSFYLSR.D "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1600.8249 -1 45324 22326 2 1600.824905 801.4197 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.84 3995.9 - 1.56E+06 - - - -0.0237 - 2.334 0.48 - 259.8 1 2 0 0 13 0 0 0 0.00E+00 0.00E+00 - - - 4.7616 1 230117_WJC_METTL3_WT_vs_EV_F05.22331.22331.3 2.35E-06 17/52 K.ILGGSVLHLVLALR.G sp|Q15843|NEDD8_HUMAN 1 1459.9239 -1 45329 22331 3 1459.925984 487.6486 NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1 9.76 3996.3 - 1.04E+06 - - - 1.4487 - 2.996 0.551 - 442.1 1 2 0 0.0021 14 0 0 0 0.00E+00 0.00E+00 - - - 7.5986 0.9998 230117_WJC_METTL3_WT_vs_EV_F05.22332.22332.3 0.000129 Dec-64 R.LLQQVGTVAQLWIYPVK.S "sp|Q5VT66|MARC1_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 2 1955.1244 -1 45330 22332 3 1955.128768 652.7154 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 8.59 3996.4 - 937058 - - - 2.2239 - 2.263 0.398 - 164.7 1 2 0 0.0043 17 0 0 0 0.00E+00 0.00E+00 - - - 5.0393 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.22337.22337.2 0.0382 16-Sep K.AFLLESLLK.N sp|Q96JM3|CHAP1_HUMAN 1 1032.6219 3.34 45334 22337 2 1032.624203 517.3182 Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2 6.05 3996.9 - 4.41E+06 - - - 2.1983 - 1.799 0.393 - 257.2 1 2 0 0.0023 9 0 0 0 6.64E+06 1.99E+06 - - - 3.6419 1 230117_WJC_METTL3_WT_vs_EV_F05.22338.22338.2 2.54E-07 14/24 R.DLYEDELVPLFEK.A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1608.7923 -1 45335 22338 2 1608.793758 805.4034 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3997 - 4.02E+06 - - - 0.9025 - 2.659 0.593 - 502.7 1 2 0 0.0015 13 0 0 0 0.00E+00 0.00E+00 - - - 5.9304 1 230117_WJC_METTL3_WT_vs_EV_F05.22339.22339.2 2.84E-06 15/24 R.DLYEDELVPLFEK[136.11].A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1616.8065 -1 45336 22339 2 1616.810497 809.4105 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3997.1 - 3.52E+06 - - - 2.4684 - 2.554 0.603 - 545.8 1 2 0 0.004 13 0 0 0 0.00E+00 0.00E+00 - - - 5.9 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.22340.22340.2 0.00107 13/24 R.DILVEADSLWVVK[136.11].M sp|Q15208|STK38_HUMAN 1 1493.8221 -1 45337 22340 2 1493.826564 747.9183 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.03 3997.1 - 1.94E+06 - - - 2.991 - 2.751 0.348 - 463.8 1 2 0 0.0045 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2072 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.22345.22345.3 8.01E-07 15/60 K.AAGVNVEPFWPGLFAK[136.11].A sp|P05386|RLA1_HUMAN 1 1709.9021 -1 45342 22345 3 1709.906544 570.9746 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3997.6 - 1.02E+06 - - - 2.6118 - 2.675 0.477 - 158.3 1 2 0 0.0045 16 0 0 0 0.00E+00 0.00E+00 - - - 6.3815 1 230117_WJC_METTL3_WT_vs_EV_F05.22346.22346.3 2.60E-07 14/48 R.DLYEDELVPLFEK[136.11].A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1616.8065 -1 45343 22346 3 1616.810169 539.9428 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3997.7 - 886774 - - - 2.2656 - 2.604 0.586 - 318.3 1 2 0 0.0037 13 0 0 0 0.00E+00 0.00E+00 - - - 7.6671 0.9988 230117_WJC_METTL3_WT_vs_EV_F05.22348.22348.2 0.561 20-Aug R.IPLLLTSLSFK[136.11].V "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1238.773 -1 45345 22348 2 1238.775889 620.3938 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.75 3997.9 - 814664 - - - 2.3636 - 1.569 0.3 - 117.2 1 2 0 0.0029 11 0 0 0 0.00E+00 0.00E+00 - - - 2.4744 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22350.22350.3 0.00192 Nov-52 K.ILGGSVLHLVLALR[166.11].G sp|Q15843|NEDD8_HUMAN 1 1469.9321 -1 45347 22350 3 1469.936572 490.9847 NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1 9.76 3998.2 - 748482 - - - 3.0158 - 1.777 0.431 - 130.2 1 2 0 0.0044 14 0 0 0 0.00E+00 0.00E+00 - - - 4.8719 1 230117_WJC_METTL3_WT_vs_EV_F05.22358.22358.3 4.43E-09 24/56 R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 2.14 45354 22358 3 1555.904433 519.6409 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3999.2 - 8.07E+07 - - - 2.3665 - 3.686 0.601 - 571.9 1 2 0 0.0037 15 0 0 0 9.59E+07 4.48E+07 - - - 8.6436 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.22360.22360.3 9.02E-05 Dec-56 R.GVMLAVDAVIAELK[136.11]K[136.11].Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1571.9292 -1 45356 22360 3 1571.931171 524.9837 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3999.3 - 3.70E+07 - - - 1.285 - 2.138 0.517 - 134.5 1 2 0 0.002 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2863 1 230117_WJC_METTL3_WT_vs_EV_F05.22361.22361.3 7.50E-07 22/56 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 -1 45357 22361 3 1581.910378 528.3103 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 3999.3 - 1.40E+07 - - - 0.8667 - 3.84 0.523 - 1004.4 1 2 0 0.0014 15 0 0 0 0.00E+00 0.00E+00 - - - 7.8814 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22363.22363.2 0.00161 20-Nov K.GIVLLEELLPK.G sp|Q9Y3D6|FIS1_HUMAN 1 1222.7537 -1 45359 22363 2 1222.755972 612.3841 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 4.53 3999.4 - 1.16E+07 - - - 1.8777 - 2.074 0.432 - 477.4 1 2 0 0.0023 11 0 0 0 0.00E+00 0.00E+00 - - - 4.2044 1 230117_WJC_METTL3_WT_vs_EV_F05.22364.22364.2 3.49E-07 13/28 R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 -1 45360 22364 2 1555.90323 778.9577 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3999.4 - 1.00E+07 - - - 1.5933 - 3.039 0.501 - 555 1 2 0 0.0025 15 0 0 0 0.00E+00 0.00E+00 - - - 5.4734 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.22365.22365.2 0.000386 20-Sep K.GIVLLEELLPK[136.11].G sp|Q9Y3D6|FIS1_HUMAN 1 1230.7679 -1 45361 22365 2 1230.769721 616.3912 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 4.53 3999.5 - 7.09E+06 - - - 1.4991 - 1.995 0.456 - 248.4 1 2 0 0.0018 11 0 0 0 0.00E+00 0.00E+00 - - - 4.2768 0.9954 230117_WJC_METTL3_WT_vs_EV_F05.22404.22404.2 0.684 16-Aug R.IAIYELLFK[136.11].E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1116.6674 4.98 45396 22404 2 1116.673102 559.341 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4003.7 - 1.05E+06 - - - 5.0767 - 1.547 0.353 - 137.4 1 2 0 0.0057 9 0 0 0 2.04E+07 4.09E+06 - - - 2.9088 1 230117_WJC_METTL3_WT_vs_EV_F05.22405.22405.2 6.18E-05 13/26 R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 -1 45397 22405 2 1486.878143 744.4432 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4003.8 - 526164 - - - 4.2035 - 2.75 0.501 - 560.7 1 2 0 0.0063 14 0 0 0 0.00E+00 0.00E+00 - - - 5.278 0.9996 230117_WJC_METTL3_WT_vs_EV_F05.22991.22991.2 0.00377 16-Oct R.IAIYELLFK[136.11].E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1116.6674 1.43 45405 22991 2 1116.669061 559.341 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4119.5 - 1.07E+06 - - - 1.4579 - 2.139 0.303 - 233.5 1 2 0 0.0016 9 0 0 0 2.05E+08 1.43E+08 - - - 3.4781 0.9995 230117_WJC_METTL3_WT_vs_EV_F05.22993.22993.2 0.00489 13/16 R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.43 45407 22993 2 1108.655208 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4119.7 - 1.69E+06 - - - 1.7814 - 2.278 0.24 - 347.5 1 2 0 0.002 9 0 0 0 2.05E+08 1.43E+08 - - - 3.1949 0.9796 230117_WJC_METTL3_WT_vs_EV_F05.22995.22995.2 8.42E-05 17/26 R.RLNIPVLQDDGFLF.L sp|Q86U44|MTA70_HUMAN 1 1645.8828 47.16 45409 22995 2 1645.885536 823.9487 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 4119.9 - 290503 - - - 1.6672 - 2.47 0.438 - 589.4 1 1 0 0.0027 14 0 0 0 1.44E+07 3.06E+05 - - - 4.5443 1 230117_WJC_METTL3_WT_vs_EV_F05.23001.23001.2 2.59E-08 17/26 K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.59 45415 23001 2 1618.96854 810.4902 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4120.7 - 155362 - - - 1.6961 - 2.74 0.556 - 508.1 1 2 0 0.0027 14 0 0 0 2.89E+07 1.82E+07 - - - 5.6762 1 230117_WJC_METTL3_WT_vs_EV_F05.23002.23002.2 1.89E-11 20/28 R.LTSFIGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1516.8865 7.67 45416 23002 2 1516.889419 759.4505 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 4120.8 - 139872 - - - 1.9369 - 3.31 0.622 - 1296.2 1 2 0 0.0029 15 0 0 0 1.99E+07 2.59E+06 - - - 6.5769 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.23006.23006.3 0.000548 15/52 K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.59 45420 23006 3 1618.970407 540.6625 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4121.4 - 107586 - - - 2.8493 - 2.49 0.491 - 281.8 1 2 0 0.0046 14 0 0 0 1.22E+07 7.64E+06 - - - 6.4373 1 230117_WJC_METTL3_WT_vs_EV_F05.23007.23007.2 1.31E-07 15/26 K.ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1626.98 1.59 45421 23007 2 1626.983136 814.4973 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4121.5 - 101763 - - - 1.9312 - 2.496 0.575 - 518.4 1 2 0 0.0031 14 0 0 0 2.89E+07 1.82E+07 - - - 5.5823 1 230117_WJC_METTL3_WT_vs_EV_F05.23008.23008.2 2.64E-06 13/24 K.SLEEIYLFSLPIK[136.11].E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN,tr|H3BNG3|H3BNG3_HUMAN,tr|H0YE27|H0YE27_HUMAN" 7 1558.8738 0.25 45422 23008 2 1558.877012 780.4442 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.53 4121.6 - 100934 - - - 2.0624 - 2.777 0.48 - 523.6 1 2 0 0.0032 13 0 0 0 2.05E+06 8.21E+06 - - - 5.2066 1 230117_WJC_METTL3_WT_vs_EV_F05.23009.23009.3 6.05E-05 16/52 R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 4.06 45423 23009 3 1486.874564 496.6312 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4121.7 - 99540.4 - - - 1.7964 - 2.828 0.56 - 328.2 1 2 0 0.0027 14 0 0 0 5.89E+06 1.45E+06 - - - 7.5454 1 230117_WJC_METTL3_WT_vs_EV_F05.23010.23010.2 0.00305 15/26 R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 5.49 45424 23010 2 1486.875437 744.4432 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4121.9 - 83603.9 - - - 2.3835 - 2.679 0.493 - 691.9 1 2 0 0.0035 14 0 0 0 6.32E+06 1.15E+06 - - - 5.1541 1 230117_WJC_METTL3_WT_vs_EV_F05.23012.23012.3 7.21E-08 22/56 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 6.44 45425 23012 3 1581.913414 528.3103 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4122.1 - 2.15E+07 - - - 2.7859 - 3.702 0.518 - 962.7 1 2 0 0.0044 15 0 0 0 2.97E+07 4.62E+06 - - - 7.7293 1 230117_WJC_METTL3_WT_vs_EV_F05.23013.23013.2 0.000409 20-Dec K.GIVLLEELLPK.G sp|Q9Y3D6|FIS1_HUMAN 1 1222.7537 1.41 45426 23013 2 1222.756437 612.3841 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 4.53 4122.2 - 2.57E+06 - - - 2.258 - 2.354 0.454 - 613.5 1 2 0 0.0028 11 0 0 0 4.27E+06 3.02E+06 - - - 4.7094 1 230117_WJC_METTL3_WT_vs_EV_F05.23014.23014.2 0.00473 15/28 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 7.05 45427 23014 2 1581.907683 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4122.2 - 1.96E+07 - - - -0.837 - 2.98 0.557 - 821.1 1 2 0 -0.0013 15 0 0 0 3.33E+07 4.72E+06 - - - 5.8391 0.9999 230117_WJC_METTL3_WT_vs_EV_F05.23016.23016.3 4.39E-05 Dec-56 R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 1268.27 45429 23016 3 1555.899449 519.6409 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 4122.3 - 1.47E+07 - - - -0.8368 - 2.266 0.511 - 138.6 1 2 0 -0.0013 15 0 0 0 1.95E+07 1.54E+04 - - - 6.3713 1 230117_WJC_METTL3_WT_vs_EV_F05.23017.23017.2 2.90E-09 18/30 K.LGFAGLVQEISFGTTK.D "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1666.893 5.28 45430 23017 2 1666.890915 834.4538 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 4122.3 - 9.35E+06 - - - -1.2646 - 3.598 0.646 - 933.2 1 2 0 -0.0021 16 0 0 0 1.72E+07 3.25E+06 - - - 6.9596 0.9978 230117_WJC_METTL3_WT_vs_EV_F05.23019.23019.3 0.00638 Jun-52 K.ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1626.98 1.59 45432 23019 3 1626.977703 543.3339 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4122.4 - 5.08E+06 - - - -1.4081 - 1.55 0.341 - 44.4 1 2 0 -0.0023 14 0 0 0 1.22E+07 7.64E+06 - - - 3.5059 0.998 230117_WJC_METTL3_WT_vs_EV_F05.23023.23023.2 0.00013 26-Sep R.APIASIHSFELDLL.- sp|Q13015|AF1Q_HUMAN 1 1524.8188 - 45436 23023 2 1524.816484 763.4167 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 4.35 4122.7 - 3.45E+06 - - - -1.5156 - 1.806 0.359 - 243.6 1 2 0 -0.0023 14 0 0 0 - - - - - 3.1752 1 230117_WJC_METTL3_WT_vs_EV_F05.23024.23024.2 8.03E-06 13/24 K.SLEEIYLFSLPIK.E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN,tr|H3BNG3|H3BNG3_HUMAN,tr|H0YE27|H0YE27_HUMAN" 7 1550.8596 0.25 45437 23024 2 1550.870983 776.4371 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.53 4122.7 - 3.42E+06 - - - 7.3417 - 2.674 0.534 - 548.6 1 2 0 0.0114 13 0 0 0 2.05E+06 8.21E+06 - - - 5.5059 1 230117_WJC_METTL3_WT_vs_EV_F05.23025.23025.2 6.91E-09 22-Oct R.TFC[160.03]QLILDPIFK.V sp|P13639|EF2_HUMAN 1 1493.7952 -1 45438 23025 2 1493.794885 747.9049 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.5 4122.8 - 2.95E+06 - - - -0.2263 - 1.964 0.553 - 350.4 1 2 0 -0.0003 12 0 0 0 0.00E+00 0.00E+00 - - - 4.9013 1 230117_WJC_METTL3_WT_vs_EV_F05.23026.23026.2 5.66E-05 13/28 R.QVLLSAAEAAEVILR[166.11].V sp|P78371|TCPB_HUMAN 1 1591.9173 -1 45439 23026 2 1591.915802 796.9659 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4122.8 - 2.85E+06 - - - -0.9266 - 2.866 0.537 - 581.3 1 2 0 -0.0015 15 0 0 0 0.00E+00 0.00E+00 - - - 5.5955 0.9963 230117_WJC_METTL3_WT_vs_EV_F05.23028.23028.3 0.0635 Jul-56 R.LTSFIGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1516.8865 -1 45441 23028 3 1516.884928 506.6361 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 4123 - 2.57E+06 - - - -1.0238 - 1.675 0.269 - 81.1 1 2 0 -0.0016 15 0 0 0 0.00E+00 0.00E+00 - - - 2.8846 1 230117_WJC_METTL3_WT_vs_EV_F05.23029.23029.2 3.84E-05 26-Oct R.LLVPTQFVGAIIGK[136.11].E "sp|O00425|IF2B3_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 3 1462.9003 -1 45442 23029 2 1462.8985 732.4574 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 4123.1 - 2.42E+06 - - - -1.2215 - 2.184 0.556 - 227.9 1 2 0 -0.0018 14 0 0 0 0.00E+00 0.00E+00 - - - 5.1073 1 230117_WJC_METTL3_WT_vs_EV_F05.23030.23030.2 5.50E-06 22-Oct R.LLTSFLPAQLLR.L "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|H0YFX4|H0YFX4_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 14 1370.8286 -1 45443 23030 2 1370.828233 686.4216 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 9.75 4123.2 - 1.96E+06 - - - -0.2473 - 2.083 0.529 - 262.4 1 2 0 -0.0003 12 0 0 0 0.00E+00 0.00E+00 - - - 4.8789 0.9987 230117_WJC_METTL3_WT_vs_EV_F05.23031.23031.2 0.0422 20-Jul K.GIVLLEELLPK[136.11].G sp|Q9Y3D6|FIS1_HUMAN 1 1230.7679 -1 45444 23031 2 1230.766559 616.3912 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 4.53 4123.3 - 1.88E+06 - - - -1.0701 - 1.751 0.372 - 145.3 1 2 0 -0.0013 11 0 0 0 0.00E+00 0.00E+00 - - - 3.3036 1 230117_WJC_METTL3_WT_vs_EV_F05.23033.23033.2 6.45E-08 17/30 K.LGFAGLVQEISFGTTK[136.11].D "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1674.9072 -1 45445 23033 2 1674.907247 838.4609 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 4123.6 - 427319 - - - 0.0143 - 3.434 0.536 - 763.4 1 2 0 0 16 0 0 0 0.00E+00 0.00E+00 - - - 6.0331 0.875 230117_WJC_METTL3_WT_vs_EV_F05.23034.23034.2 0.00433 22-Aug L.AAAAAGLAVYR[166.11]R[166.11].K "sp|Q92922|SMRC1_HUMAN,tr|F8WE13|F8WE13_HUMAN" 2 1208.6893 -1 45446 23034 2 1208.68767 605.3519 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 10.84 4123.8 - 522085 - - - -1.332 - 1.953 0.315 - 185.2 1 1 0 -0.0016 12 0 0 0 0.00E+00 0.00E+00 - - - 3.1283 0.9676 230117_WJC_METTL3_WT_vs_EV_F05.23036.23036.2 7.01E-06 26-Sep R.DYLHLPPEIVPATL.H "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1576.8501 - 45448 23036 2 1576.854204 789.4323 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.35 4124 - 715098 - - - 2.6058 - 1.76 0.508 - 210.7 1 1 0 0.0041 14 0 0 0 - - - - - 4.2104 1 230117_WJC_METTL3_WT_vs_EV_F05.23038.23038.2 3.41E-06 Oct-32 R.WVGGPEIELIAIATGGR.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1737.9414 20.66 45450 23038 2 1737.943041 869.978 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 4124.3 - 501546 - - - 0.9615 - 2.171 0.55 - 251.5 1 2 0 0.0017 17 0 0 0 3.11E+06 1.50E+05 - - - 5.0086 1 230117_WJC_METTL3_WT_vs_EV_F05.23039.23039.2 7.51E-07 28-Sep K.FDVILLEPPLEEYYR.E "sp|Q9HCE5|MET14_HUMAN,tr|D6RBL4|D6RBL4_HUMAN" 2 1894.9717 -1 45451 23039 2 1894.974448 948.4931 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4 4124.4 - 377693 - - - 1.4676 - 2.089 0.586 - 163.2 1 2 0 0.0028 15 0 0 0 0.00E+00 0.00E+00 - - - 5.1795 0.9997 230117_WJC_METTL3_WT_vs_EV_F05.23040.23040.2 7.48E-05 18-Sep R.DEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1329.6605 -1 45452 23040 2 1329.662735 665.8375 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 4124.6 - 354145 - - - 1.6779 - 1.934 0.499 - 311.6 1 2 0 0.0022 10 0 0 0 0.00E+00 0.00E+00 - - - 4.567 0.9979 230117_WJC_METTL3_WT_vs_EV_F05.23046.23046.2 0.133 18-Mar R.DEVFEYIIFR[166.11].G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1339.6688 -1 45458 23046 2 1339.671441 670.8417 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 4125.3 - 286990 - - - 1.9908 - 0.865 0.426 - 37.7 1 2 0 0.0027 10 0 0 0 0.00E+00 0.00E+00 - - - 1.7818 0.9724 230117_WJC_METTL3_WT_vs_EV_F05.23086.23086.2 0.808 22-Jul R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 45474 23086 2 1603.772715 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 4131.6 - 60976.1 - - - 5.4715 - 1.252 0.239 - 99.8 1 2 0 0.0088 12 0 0 0 2.98E+06 0.00E+00 - - - 1.3948 0.8559 230117_WJC_METTL3_WT_vs_EV_F06.02999.02999.2 2.62 12-Jun K.ATVEDEK.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 790.3709 4.39 45497 2999 2 790.368825 396.1927 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 1290.5 - 174416 - - - -2.5785 - 0.83 0.201 - 78.2 1 2 0 -0.002 7 0 0 0 3.16E+06 7.19E+05 - - - -0.0654 0.9684 230117_WJC_METTL3_WT_vs_EV_F06.03464.03464.2 0.078 12-May K.HPELADK.N "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 808.4079 1.56 45504 3464 2 808.405318 405.2112 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 5.32 1373.4 - 163121 - - - -3.2162 - 1.121 0.269 - 76.3 1 2 0 -0.0026 7 0 0 0 1.01E+07 6.49E+06 - - - 1.3889 0.9902 230117_WJC_METTL3_WT_vs_EV_F06.04107.04107.2 0.265 12-Jun R.NSTIPTK.Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 759.4127 9.29 45522 4107 2 759.412672 380.7136 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 1488.5 - 372465 - - - 0.004 - 1.203 0.153 - 142.3 1 2 0 0 7 0 0 0 2.52E+07 2.71E+06 - - - 0.7567 0.997 230117_WJC_METTL3_WT_vs_EV_F06.04122.04122.2 0.384 12-Jul R.FTDEESR[166.11].V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 892.3802 0.7 45524 4122 2 892.380019 447.1974 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1491 - 657692 - - - -0.1983 - 1.323 0.255 - 173.2 1 2 0 -0.0002 7 0 0 0 2.07E+07 2.95E+07 - - - 1.8113 0.996 230117_WJC_METTL3_WT_vs_EV_F06.04127.04127.2 0.02 18-Aug R.IAGQVAAANK.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 941.5294 1.58 45525 4127 2 941.528167 471.772 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1491.7 - 126611 - - - -1.3414 - 1.504 0.276 - 140.9 1 2 0 -0.0013 10 0 0 0 1.40E+07 8.84E+06 - - - 2.2183 0.9933 230117_WJC_METTL3_WT_vs_EV_F06.04201.04201.2 0.0346 14-Jul R.NTEEEGLK[136.11].Y "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 926.4436 1.39 45529 4201 2 926.441126 464.2291 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.25 1504.5 - 619237 - - - -2.7147 - 1.487 0.317 - 290.3 1 2 0 -0.0025 8 0 0 0 3.20E+07 2.30E+07 - - - 2.5782 0.993 230117_WJC_METTL3_WT_vs_EV_F06.04231.04231.2 0.436 12-Jul R.EAQVNVR[166.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 824.438 0.05 45531 4231 2 824.437464 413.2263 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1509.6 - 771223 - - - -0.6332 - 1.364 0.174 - 342 1 2 0 -0.0005 7 0 0 0 1.54E+07 3.07E+08 - - - 1.3096 0.9907 230117_WJC_METTL3_WT_vs_EV_F06.04232.04232.2 0.272 12-Jun R.EAQVNVR.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 814.4297 0.05 45532 4232 2 814.428668 408.2221 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1509.8 - 581998 - - - -1.2868 - 1.201 0.242 - 233.3 1 2 0 -0.001 7 0 0 0 1.55E+07 3.01E+08 - - - 1.4084 0.992 230117_WJC_METTL3_WT_vs_EV_F06.04304.04304.2 0.0366 12-Jun K.HTLTQIK.D sp|P40227|TCPZ_HUMAN 1 839.4865 10.3 45533 4304 2 839.485659 420.7505 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 8.76 1522.7 - 339343 - - - -1.0042 - 1.196 0.241 - 89.8 1 2 0 -0.0008 7 0 0 0 9.14E+06 8.87E+05 - - - 1.3879 0.9778 230117_WJC_METTL3_WT_vs_EV_F06.04361.04361.2 0.0947 12-Jun R.TATFQQR.F "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 850.4297 1.05 45537 4361 2 850.428032 426.2221 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.41 1532.5 - 141584 - - - -1.9802 - 1.142 0.217 - 185.4 1 2 0 -0.0017 7 0 0 0 3.79E+06 3.61E+06 - - - 1.064 0.8661 230117_WJC_METTL3_WT_vs_EV_F06.04418.04418.2 4.81 12-May K.EQSIVEK.F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 831.4338 999.51 45541 4418 2 831.432494 416.7242 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 1542.2 - 2.55E+07 - - - -1.5684 - 1.181 0.02 - 168.6 2 2 0 -0.0013 7 0 0 0 8.12E+08 8.13E+05 - - - -0.419 0.9929 230117_WJC_METTL3_WT_vs_EV_F06.04502.04502.2 0.303 16-Jul K.VLENAEGAR.T "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 957.488 11.35 45549 4502 2 957.486052 479.7513 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.53 1556.2 - 294522 - - - -1.9917 - 1.373 0.283 - 196.9 1 2 0 -0.0019 9 0 0 0 6.11E+06 5.39E+05 - - - 2.0477 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.04522.04522.2 0.127 14-Jul K.SVLADQGK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 816.4341 0.45 45550 4522 2 816.434463 409.2243 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.55 1559.7 - 2.71E+06 - - - 0.4054 - 1.369 0.194 - 176.2 1 2 0 0.0003 8 0 0 0 3.22E+07 7.18E+07 - - - 1.421 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.05009.05009.2 0.0884 16-Aug K.TIAPQNAPR.D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 966.5247 0.36 45555 5009 2 966.524862 484.2696 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1648.4 - 331420 - - - 0.1893 - 1.384 0.259 - 217.6 1 2 0 0.0002 9 0 0 0 2.84E+07 7.79E+07 - - - 1.8941 0.9717 230117_WJC_METTL3_WT_vs_EV_F06.05015.05015.2 0.0974 16-Sep K.TIAPQNAPR[166.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 976.5329 0.73 45556 5015 2 976.530007 489.2738 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1649.4 - 679202 - - - -3.0127 - 1.432 0.176 - 295.2 1 2 0 -0.0029 9 0 0 0 2.71E+07 3.69E+07 - - - 1.3788 0.8593 230117_WJC_METTL3_WT_vs_EV_F06.05136.05136.2 2.28 12-Jun K.LVEESVK[136.11].H "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 810.4578 0.27 45558 5136 2 810.45393 406.2362 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 1670.5 - 552085 - - - -4.817 - 1.338 0.129 - 131.7 1 2 0 -0.0039 7 0 0 0 6.59E+06 2.44E+07 - - - 0.9152 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.05348.05348.2 0.000878 12-Jul K.SDSFAPK[136.11].T "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 758.369 0.001 45569 5348 2 758.370074 380.1918 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.55 1707.5 - 529345 - - - 1.3911 - 1.648 0.329 - 217.8 1 2 0 0.0011 7 0 0 0 0.00E+00 2.49E+07 - - - 3.0536 0.9894 230117_WJC_METTL3_WT_vs_EV_F06.05485.05485.2 10.1 12-Jun K.ITITNDK.G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 803.4389 12.48 45576 5485 2 803.440869 402.7267 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1732.3 - 556897 - - - 2.4719 - 1.238 0.126 - 118.3 1 2 0 0.002 7 0 0 0 1.24E+08 9.97E+06 - - - 0.6475 0.9956 230117_WJC_METTL3_WT_vs_EV_F06.05491.05491.2 1.5 12-May K.ITITNDK[136.11].G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 811.4531 12.47 45577 5491 2 811.454766 406.7338 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1733.3 - 80367 - - - 2.0741 - 1.144 0.231 - 77.4 1 2 0 0.0017 7 0 0 0 1.24E+08 9.97E+06 - - - 1.1729 0.9511 230117_WJC_METTL3_WT_vs_EV_F06.05688.05688.2 2.18 16-May R.VADNSFDAK.R "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 965.4454 999 45579 5688 2 965.446746 483.73 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.21 1769.1 - 132772 - - - 1.3683 - 0.791 0.161 - 44.8 2 2 0 0.0013 9 0 0 0 5.39E+06 0.00E+00 - - - -0.583 0.9757 230117_WJC_METTL3_WT_vs_EV_F06.05851.05851.2 0.847 12-May K.LAEPYGK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 784.4211 1.46 45587 5851 2 784.420788 393.2178 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1798 - 133999 - - - -0.3404 - 0.925 0.198 - 88.8 1 2 0 -0.0003 7 0 0 0 1.89E+07 1.29E+07 - - - 0.2563 0.9942 230117_WJC_METTL3_WT_vs_EV_F06.05862.05862.2 0.422 12-Jun K.LAEPYGK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 776.4069 1.38 45588 5862 2 776.407316 389.2107 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1799.9 - 324509 - - - 0.5938 - 1.293 0.149 - 154.4 1 2 0 0.0005 7 0 0 0 1.75E+07 1.27E+07 - - - 0.9556 0.9672 230117_WJC_METTL3_WT_vs_EV_F06.06023.06023.2 0.0829 16-Jun R.VNGSLAVSR[166.11].A "sp|O75688|PPM1B_HUMAN,sp|P35813|PPM1A_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 5 911.5064 0.27 45593 6023 2 911.504162 456.7605 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 9.72 1827.7 - 144667 - - - -2.4553 - 1.34 0.149 - 83 1 2 0 -0.0022 9 0 0 0 1.56E+06 5.76E+06 - - - 0.9875 0.9941 230117_WJC_METTL3_WT_vs_EV_F06.06033.06033.2 0.0433 18-Jul K.GSAITGPVAK[136.11].E "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 907.5218 1.69 45594 6033 2 907.520208 454.7682 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.75 1829.4 - 155016 - - - -1.7895 - 1.328 0.307 - 141.5 1 2 0 -0.0016 10 0 0 0 1.54E+07 9.13E+06 - - - 2.0998 0.885 230117_WJC_METTL3_WT_vs_EV_F06.06084.06084.2 6.17 14-May R.STLEPVEK.A "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 901.4757 12.31 45598 6084 2 901.477911 451.7451 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.53 1838.3 - 202804 - - - 2.4937 - 0.981 0.045 - 62.2 4 2 0 0.0022 8 0 0 0 6.60E+07 5.36E+06 - - - -0.9541 0.957 230117_WJC_METTL3_WT_vs_EV_F06.06195.06195.2 4 14-May R.LEELDADK.A "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 931.4498 1.82 45601 6195 2 931.45026 466.7322 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 3.92 1859 - 193534 - - - 0.4488 - 1.163 0.034 - 57.9 2 2 0 0.0004 8 0 0 0 2.59E+07 1.42E+07 - - - -0.3871 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.06203.06203.2 0.00763 16-Sep R.VTDALNATR.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 959.5036 2.13 45602 6203 2 959.505171 480.7591 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1860.5 - 224477 - - - 1.6279 - 1.809 0.293 - 288.9 1 2 0 0.0016 9 0 0 0 7.50E+07 3.52E+07 - - - 2.9195 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.06215.06215.2 0.000177 16-Oct R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 2.13 45603 6215 2 969.512576 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1862.6 - 502394 - - - 0.7189 - 2.036 0.454 - 420.4 1 2 0 0.0007 9 0 0 0 7.49E+07 3.52E+07 - - - 4.4509 0.906 230117_WJC_METTL3_WT_vs_EV_F06.06603.06603.2 2.54 14-Apr K.VISELNGK[136.11].N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 866.4953 1.46 45618 6603 2 866.495163 434.2549 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1932.2 - 162361 - - - -0.1385 - 0.873 0.105 - 43.8 2 2 0 -0.0001 8 0 0 0 1.67E+07 1.15E+07 - - - -0.7276 0.9634 230117_WJC_METTL3_WT_vs_EV_F06.06626.06626.2 0.951 14-May K.VISELNGK.N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 858.4811 1.35 45619 6626 2 858.482692 430.2478 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1936.5 - 338792 - - - 1.8742 - 0.827 0.16 - 73.8 1 2 0 0.0016 8 0 0 0 1.70E+07 1.26E+07 - - - -0.3506 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.06889.06889.2 0.00259 24-Aug K.GPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1199.6146 999 45629 6889 2 1199.614162 600.8146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1982.3 - 68542.1 - - - -0.3785 - 1.549 0.45 - 142.5 1 2 0 -0.0005 13 0 0 0 8.03E+06 0.00E+00 - - - 3.4877 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.06903.06903.2 0.2 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 232.78 45631 6903 2 776.383414 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1984.6 - 563709 - - - 2.2038 - 1.412 0.225 - 179.2 1 2 0 0.0017 7 0 0 0 5.54E+09 2.38E+07 - - - 1.7955 0.9915 230117_WJC_METTL3_WT_vs_EV_F06.06904.06904.2 0.353 12-Jun K.IIAPPER[166.11].K "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 12 804.4733 0.75 45632 6904 2 804.473827 403.2439 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 1984.7 - 143140 - - - 0.6451 - 1.125 0.169 - 133.3 1 2 0 0.0005 7 0 0 0 3.25E+07 4.36E+07 - - - 0.6623 0.951 230117_WJC_METTL3_WT_vs_EV_F06.06937.06937.2 5.24 14-Jul R.GTLDPVEK.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 857.4494 13.19 45633 6937 2 857.448952 429.732 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.37 1990.7 - 1.22E+06 - - - -0.5785 - 1.15 0.056 - 131.6 1 2 0 -0.0005 8 0 0 0 9.84E+07 7.46E+06 - - - -0.124 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.07006.07006.2 0.0239 16-Aug K.SAAMTLNER[166.11].F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1001.484 0.78 45638 7006 2 1001.485129 501.7493 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 2002.5 - 327392 - - - 1.1773 - 1.462 0.365 - 181.4 1 2 0 0.0012 9 0 0 0 1.68E+07 2.16E+07 - - - 2.8353 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.07015.07015.2 0.0754 16-Aug K.SAAMTLNER.F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 991.4757 0.78 45640 7015 2 991.476377 496.7451 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 2003.9 - 223988 - - - 0.703 - 1.576 0.32 - 268.5 1 2 0 0.0007 9 0 0 0 1.68E+07 2.16E+07 - - - 2.7203 0.9964 230117_WJC_METTL3_WT_vs_EV_F06.07100.07100.2 0.561 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 0.9 45643 7100 2 776.381442 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2018.8 - 486884 - - - -0.3362 - 1.46 0.199 - 179.6 1 2 0 -0.0003 7 0 0 0 8.49E+07 9.49E+07 - - - 1.7098 0.9781 230117_WJC_METTL3_WT_vs_EV_F06.07135.07135.2 0.0962 14-Jun K.GANPVEIR.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 854.461 1.81 45646 7135 2 854.460067 428.2378 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 2024.8 - 258247 - - - -1.1106 - 1.113 0.176 - 163.7 1 2 0 -0.0009 8 0 0 0 6.18E+07 3.41E+07 - - - 0.6635 0.999 230117_WJC_METTL3_WT_vs_EV_F06.07182.07182.2 0.00711 14-Jul K.GANPVEIR[166.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 864.4693 1.84 45652 7182 2 864.469777 433.2419 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 2032.6 - 454624 - - - 0.568 - 1.306 0.359 - 189.1 1 2 0 0.0005 8 0 0 0 6.19E+07 3.37E+07 - - - 2.4976 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.07233.07233.2 0.409 14-Aug K.VGEVIVTK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.5208 2.04 45656 7233 2 851.523199 426.7677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2041.7 - 141413 - - - 2.8537 - 1.86 0.18 - 177.7 2 2 0 0.0024 8 0 0 0 1.10E+08 5.41E+07 - - - 2.1069 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.07241.07241.2 0.0189 14-Aug K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 2.04 45657 7241 2 843.508479 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2043.1 - 494362 - - - 2.2644 - 1.859 0.394 - 167.8 1 2 0 0.0019 8 0 0 0 1.10E+08 5.41E+07 - - - 3.8205 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.07503.07503.2 0.04 16-Jul K.VTMQNLNDR.L "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 8 1089.5237 999 45675 7503 2 1089.524344 545.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.81 2088.3 - 219211 - - - 0.5984 - 1.369 0.306 - 162.8 1 2 0 0.0007 9 0 0 0 7.40E+06 0.00E+00 - - - 2.2096 0.991 230117_WJC_METTL3_WT_vs_EV_F06.07648.07648.2 0.581 16-Jun R.VLNTNIDGR[166.11].R "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1010.5384 1.56 45692 7648 2 1010.538193 506.2765 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.81 2112.5 - 124363 - - - -0.2325 - 1.157 0.216 - 86.7 2 2 0 -0.0002 9 0 0 0 2.86E+07 1.83E+07 - - - 0.9237 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.07652.07652.2 0.154 14-Jul R.VLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 815.4753 0.93 45693 7652 2 815.475673 408.7449 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 2113 - 414332 - - - 0.4954 - 1.423 0.316 - 212.1 1 2 0 0.0004 8 0 0 0 3.06E+07 3.29E+07 - - - 2.4388 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.07666.07666.2 0.00197 16-Sep R.VLNTNIDGR.R "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1000.5302 1.68 45694 7666 2 1000.529688 501.2724 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.81 2115.6 - 468794 - - - -0.4698 - 1.937 0.355 - 306.9 1 2 0 -0.0005 9 0 0 0 2.87E+07 1.71E+07 - - - 3.5756 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.07714.07714.2 0.0218 16-Jun K.DVDGAYMTK.V sp|P04264|K2C1_HUMAN 1 998.4379 81.19 45702 7714 2 998.439381 500.2262 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.21 2123 - 273458 - - - 1.4863 - 1.086 0.41 - 70.3 1 2 0 0.0015 9 0 0 0 6.53E+06 8.04E+04 - - - 2.3075 0.9111 230117_WJC_METTL3_WT_vs_EV_F06.07752.07752.2 26.4 12-Jun R.IPPVAVR[166.11].L "sp|Q14839|CHD4_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A0G2JM70|A0A0G2JM70_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|V9GYG6|V9GYG6_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 760.4835 0.001 45706 7752 2 760.483899 381.249 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 2129.4 - 354809 - - - 0.5523 - 1.033 0.032 - 101 4 2 0 0.0004 7 0 0 0 0.00E+00 5.16E+07 - - - -0.8888 0.9696 230117_WJC_METTL3_WT_vs_EV_F06.07757.07757.2 2.11 14-Jul R.FSELTAEK.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 923.46 7.44 45707 7757 2 923.463595 462.7373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2130.2 - 2.79E+06 - - - 3.8789 - 1.037 0.183 - 70.9 1 2 0 0.0036 8 0 0 0 3.94E+07 5.29E+06 - - - 0.5011 0.9769 230117_WJC_METTL3_WT_vs_EV_F06.07818.07818.2 0.000214 16-Oct Y.PDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 953.5546 999 45711 7818 2 953.556191 477.7846 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2140.6 - 554523 - - - 1.6874 - 1.838 0.46 - 362.9 1 1 0 0.0016 9 0 0 0 3.00E+07 0.00E+00 - - - 4.199 1 230117_WJC_METTL3_WT_vs_EV_F06.07844.07844.2 0.00531 13/18 R.YPDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 1116.6179 1520.9 45716 7844 2 1116.61994 559.3162 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2144.7 - 908416 - - - 1.818 - 1.95 0.564 - 614.9 1 2 0 0.002 10 0 0 0 7.63E+07 5.02E+04 - - - 5.0702 0.9065 230117_WJC_METTL3_WT_vs_EV_F06.07854.07854.2 0.142 12-Jun D.VIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 784.4807 8.3 45718 7854 2 784.481521 393.2476 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 2146.3 - 402359 - - - 1.0606 - 1.348 0.291 - 173.9 1 1 0 0.0008 7 0 0 0 6.39E+07 7.70E+06 - - - 2.1363 0.9889 230117_WJC_METTL3_WT_vs_EV_F06.07879.07879.2 0.0775 14-Jul K.HVVFIAQR[166.11].R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 978.5639 2.88 45720 7879 2 978.569076 490.2892 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 9.76 2150.7 - 149465 - - - 5.3354 - 1.285 0.317 - 201.2 1 2 0 0.0052 8 0 0 0 8.63E+06 2.99E+06 - - - 2.137 0.9561 230117_WJC_METTL3_WT_vs_EV_F06.07891.07891.2 3.98 16-Jun K.HVVPLPDGK[136.11].S "sp|Q63HN8|RN213_HUMAN,tr|A0A0A0MTC1|A0A0A0MTC1_HUMAN,tr|A0A0A0MTR7|A0A0A0MTR7_HUMAN" 3 968.5535 0.01 45722 7891 2 968.555336 485.284 E3 ubiquitin-protein ligase RNF213 OS=Homo sapiens OX=9606 GN=RNF213 PE=1 SV=3 6.74 2152.6 - 157290 - - - 1.9307 - 1.164 0.037 - 144.1 3 2 0 0.0019 9 0 0 0 6.35E+04 1.02E+07 - - - -0.4601 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.07930.07930.2 0.00239 16-Sep R.TLLEGEESR.M sp|P04264|K2C1_HUMAN 1 1032.5088 84.73 45728 7930 2 1032.509713 517.2617 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.25 2159 - 843586 - - - 0.9288 - 1.621 0.426 - 291.2 1 2 0 0.001 9 0 0 0 4.33E+07 5.10E+05 - - - 3.5846 0.8856 230117_WJC_METTL3_WT_vs_EV_F06.07936.07936.2 32.4 12-Apr R.IPPVAVR[166.11].L "sp|Q14839|CHD4_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A0G2JM70|A0A0G2JM70_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|V9GYG6|V9GYG6_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 760.4835 0.001 45730 7936 2 760.483529 381.249 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 2159.8 - 494846 - - - 0.0657 - 0.965 0.074 - 62.5 8 2 0 0 7 0 0 0 0.00E+00 7.67E+07 - - - -0.9287 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.07970.07970.3 1.07E-06 Oct-60 K.ATAGDTHLGGEDFDNR.L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1674.7234 95.82 45738 7970 3 1674.72722 559.2484 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2165 - 139882 - - - 2.2863 - 2.188 0.495 - 67.3 1 2 0 0.0038 16 0 0 0 5.10E+06 5.33E+04 - - - 6.0667 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.08080.08080.2 0.0318 12-Aug R.FC[160.03]ALEEK.C "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 895.411 0.31 45748 8080 2 895.410541 448.7128 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2183.7 - 155850 - - - -0.4612 - 1.441 0.283 - 219.7 1 2 0 -0.0004 7 0 0 0 8.63E+06 2.78E+07 - - - 2.2887 0.9819 230117_WJC_METTL3_WT_vs_EV_F06.08105.08105.2 2.13 14-Jul K.VC[160.03]NPIITK.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 943.5161 14.84 45751 8105 2 943.515079 472.7653 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.19 2187.8 - 108358 - - - -1.0694 - 1.246 0.146 - 146 1 2 0 -0.001 8 0 0 0 9.10E+07 6.14E+06 - - - 0.7824 0.9696 230117_WJC_METTL3_WT_vs_EV_F06.08170.08170.2 0.232 14-Apr K.C[160.03]GEALGLK.Q "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 846.4269 0.54 45756 8170 2 846.426146 424.2207 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.99 2199 - 103542 - - - -0.9369 - 1.086 0.144 - 53.8 1 2 0 -0.0008 8 0 0 0 1.30E+07 2.41E+07 - - - 0.3532 0.9761 230117_WJC_METTL3_WT_vs_EV_F06.08180.08180.2 9.02 12-Jul K.VLAAVYK.A "sp|P05062|ALDOB_HUMAN,sp|P04075|ALDOA_HUMAN,sp|P09972|ALDOC_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|A8MVZ9|A8MVZ9_HUMAN,tr|A0A3B3IS80|A0A3B3IS80_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|A0A087WXX2|A0A087WXX2_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 10 762.464 1.87 45758 8180 2 762.465009 382.2393 Fructose-bisphosphate aldolase B OS=Homo sapiens OX=9606 GN=ALDOB PE=1 SV=2 8.56 2200.6 - 414726 - - - 1.3548 - 1.248 0.019 - 125.4 1 2 0 0.001 7 0 0 0 1.73E+08 9.27E+07 - - - -0.117 0.8786 230117_WJC_METTL3_WT_vs_EV_F06.08186.08186.2 0.0636 16-Oct R.PSGLLAQER[166.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 979.5326 0.78 45759 8186 2 979.5344 490.7736 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.43 2201.6 - 252191 - - - 1.8233 - 1.793 0.158 - 327.4 1 1 0 0.0018 9 0 0 0 9.60E+06 1.24E+07 - - - 1.8967 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.08192.08192.2 0.132 12-Jun K.VLAAVYK[136.11].A "sp|P05062|ALDOB_HUMAN,sp|P04075|ALDOA_HUMAN,sp|P09972|ALDOC_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|A8MVZ9|A8MVZ9_HUMAN,tr|A0A3B3IS80|A0A3B3IS80_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|A0A087WXX2|A0A087WXX2_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 10 770.4782 1.87 45760 8192 2 770.479285 386.2464 Fructose-bisphosphate aldolase B OS=Homo sapiens OX=9606 GN=ALDOB PE=1 SV=2 8.56 2202.6 - 840574 - - - 1.4394 - 1.322 0.237 - 124.8 1 2 0 0.0011 7 0 0 0 1.73E+08 9.27E+07 - - - 1.6756 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.08206.08206.2 0.0397 12-Jul R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 391.84 45765 8206 2 808.432917 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2204.6 - 864382 - - - -0.1893 - 1.515 0.269 - 103.5 1 2 0 -0.0002 7 0 0 0 1.34E+08 3.43E+05 - - - 2.3441 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.08230.08230.2 0.002 18-Nov K.LLNTVEETTK[136.11].D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1154.6274 0.1 45768 8230 2 1154.628639 578.321 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2208.6 - 486729 - - - 1.0566 - 2.247 0.376 - 362.2 1 2 0 0.0012 10 0 0 0 2.37E+06 2.36E+07 - - - 4.0776 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.08232.08232.2 0.0132 18-Oct K.LLNTVEETTK.D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1146.6132 0.1 45769 8232 2 1146.61595 574.3139 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2208.8 - 999528 - - - 2.3818 - 1.689 0.352 - 240.2 1 2 0 0.0027 10 0 0 0 2.37E+06 2.36E+07 - - - 3.103 0.9607 230117_WJC_METTL3_WT_vs_EV_F06.08254.08254.2 2.99 14-Apr K.KMDSGYRK.D sp|O95347|SMC2_HUMAN 1 983.4859 2688.8 45774 8254 2 983.487082 492.7502 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 9.7 2212.3 - 468152 - - - 1.2527 - 0.908 0.128 - 81.9 2 2 0 0.0012 8 0 0 0 5.96E+07 2.22E+04 - - - -0.4395 0.9932 230117_WJC_METTL3_WT_vs_EV_F06.08264.08264.2 0.117 14-Jul R.ILSGVVTK[136.11].M "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 823.5259 0.86 45777 8264 2 823.526229 412.7702 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 2213.7 - 390164 - - - 0.4554 - 1.5 0.083 - 109.1 1 2 0 0.0004 8 0 0 0 3.44E+07 4.00E+07 - - - 0.8768 0.999 230117_WJC_METTL3_WT_vs_EV_F06.08285.08285.2 0.0918 14-Aug R.IVVAAVAR[166.11].A "sp|Q7Z2T5|TRM1L_HUMAN,tr|X6RK96|X6RK96_HUMAN" 2 807.5206 1.62 45781 8285 2 807.521423 404.7676 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 9.75 2217.1 - 935324 - - - 1.0278 - 1.704 0.235 - 147.3 1 2 0 0.0008 8 0 0 0 5.57E+07 3.44E+07 - - - 2.3839 0.9849 230117_WJC_METTL3_WT_vs_EV_F06.08302.08302.2 0.0466 18-May R.ASAVSELSPR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1025.5381 0.82 45784 8302 2 1025.539012 513.7763 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2219.8 - 58031.5 - - - 0.8951 - 1.186 0.113 - 53.9 2 2 0 0.0009 10 0 0 0 1.11E+07 1.35E+07 - - - 0.217 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.08363.08363.2 0.0185 18-Sep R.ASAVSELSPR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1015.5298 0.82 45793 8363 2 1015.531969 508.7722 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2229.7 - 134971 - - - 2.1122 - 1.703 0.295 - 204.2 1 2 0 0.0021 10 0 0 0 1.11E+07 1.35E+07 - - - 2.7053 0.9909 230117_WJC_METTL3_WT_vs_EV_F06.08406.08406.2 3.37 12-Jun R.LLPAEVK[136.11].A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 776.4887 1.33 45798 8406 2 776.48911 389.2516 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6 2236.9 - 1.86E+06 - - - 0.4752 - 1.224 0.132 - 122.2 1 2 0 0.0004 7 0 0 0 2.46E+08 1.85E+08 - - - 0.6563 0.9141 230117_WJC_METTL3_WT_vs_EV_F06.08412.08412.2 2.21 14-May K.LIEVDDER[166.11].K "sp|P62753|RS6_HUMAN,tr|A2A3R7|A2A3R7_HUMAN" 2 997.4956 0.79 45799 8412 2 997.496666 499.7551 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 3.92 2237.9 - 108970 - - - 1.1088 - 0.872 0.076 - 51.3 2 2 0 0.0011 8 0 0 0 2.25E+06 2.83E+06 - - - -0.9456 0.9808 230117_WJC_METTL3_WT_vs_EV_F06.08434.08434.2 2 12-May K.SEITELR.R "sp|P13645|K1C10_HUMAN,sp|Q8TDM6|DLG5_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 3 846.4447 4.48 45804 8434 2 846.444496 424.2296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2241.3 - 349472 - - - -0.2375 - 1.045 0.162 - 136.6 1 2 0 -0.0002 7 0 0 0 1.31E+07 2.92E+06 - - - 0.3769 1 230117_WJC_METTL3_WT_vs_EV_F06.08462.08462.2 2.07E-06 13/20 K.FAEALGSTEAK[136.11].A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1130.5699 0.45 45809 8462 2 1130.572887 566.2922 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2245.6 - 372264 - - - 2.6385 - 2.338 0.53 - 519.1 1 2 0 0.003 11 0 0 0 6.81E+06 1.51E+07 - - - 5.2522 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.08562.08562.2 0.0877 16-Jul R.ILQDSLGGR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 967.5326 0.35 45821 8562 2 967.533162 484.7736 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2262.1 - 128164 - - - 0.5664 - 1.493 0.214 - 124.4 1 2 0 0.0005 9 0 0 0 6.50E+06 1.88E+07 - - - 1.7809 0.9823 230117_WJC_METTL3_WT_vs_EV_F06.08582.08582.2 2.33 16-Jun R.ILQDSLGGR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 957.5243 0.35 45825 8582 2 957.524644 479.7694 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2265.2 - 105106 - - - 0.3133 - 1.018 0.155 - 83.2 1 2 0 0.0003 9 0 0 0 6.50E+06 1.88E+07 - - - 0.2373 0.9783 230117_WJC_METTL3_WT_vs_EV_F06.08684.08684.2 2.52 12-Jul R.LLEQGIR.V "sp|P28340|DPOD1_HUMAN,sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 7 827.4865 1.59 45845 8684 2 827.487451 414.7505 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 6 2281.1 - 184052 - - - 1.1468 - 1.308 0.008 - 144.4 1 2 0 0.0009 7 0 0 0 3.31E+07 2.08E+07 - - - -0.0495 0.9792 230117_WJC_METTL3_WT_vs_EV_F06.08760.08760.2 0.108 12-Jul K.NIQVVVR[166.11].C "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 836.5108 0.27 45863 8760 2 836.509528 419.2627 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 9.75 2292.4 - 1.02E+06 - - - -1.4692 - 1.119 0.199 - 219.9 1 2 0 -0.0012 7 0 0 0 2.01E+07 7.37E+07 - - - 0.8667 0.9923 230117_WJC_METTL3_WT_vs_EV_F06.08824.08824.2 0.0379 12-Jul R.AMIIAER[166.11].Q "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 812.4454 1.89 45867 8824 2 812.443776 407.23 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.05 2303 - 587286 - - - -1.9731 - 1.553 0.206 - 268.9 1 2 0 -0.0016 7 0 0 0 5.84E+07 3.09E+07 - - - 1.9568 0.9941 230117_WJC_METTL3_WT_vs_EV_F06.08892.08892.2 0.574 16-Sep R.NIVEAAAVR[166.11].D "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 951.5377 1.05 45880 8892 2 951.537615 476.7761 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 6 2313.8 - 997825 - - - -0.0893 - 1.026 0.28 - 235.2 1 2 0 -0.0001 9 0 0 0 2.04E+07 1.94E+07 - - - 1.1833 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.08896.08896.2 0.000654 16-Sep R.NIVEAAAVR.D "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 941.5294 1.05 45881 8896 2 941.529231 471.772 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 6 2314.4 - 424932 - - - -0.2114 - 1.78 0.412 - 209.3 1 2 0 -0.0002 9 0 0 0 2.04E+07 1.94E+07 - - - 3.7521 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.08904.08904.2 0.716 12-Aug R.HLQLAIR[166.11].N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 859.5267 0.81 45884 8904 2 859.527294 430.7706 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2315.5 - 406172 - - - 0.6434 - 1.407 0.142 - 262.6 1 2 0 0.0006 7 0 0 0 1.09E+08 1.35E+08 - - - 1.1716 0.9941 230117_WJC_METTL3_WT_vs_EV_F06.08911.08911.2 0.165 14-May K.LVIEEAER.S sp|P50991|TCPD_HUMAN 1 957.5131 31.49 45886 8911 2 957.514002 479.7638 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.25 2316.5 - 242059 - - - 0.9305 - 1.002 0.248 - 77.5 1 2 0 0.0009 8 0 0 0 9.82E+06 3.12E+05 - - - 0.8785 0.977 230117_WJC_METTL3_WT_vs_EV_F06.08953.08953.2 0.502 12-Aug K.IIDAALR.A "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 770.465 2.25 45888 8953 2 770.463905 386.2398 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2323.8 - 2.54E+06 - - - -1.4705 - 1.252 0.141 - 206.3 1 2 0 -0.0011 7 0 0 0 2.16E+09 9.60E+08 - - - 0.7942 0.8824 230117_WJC_METTL3_WT_vs_EV_F06.09128.09128.2 8.42 12-May K.YGLAAFR[166.11].A sp|P41220|RGS2_HUMAN 1 806.4314 0.81 45915 9128 2 806.431668 404.223 Regulator of G-protein signaling 2 OS=Homo sapiens OX=9606 GN=RGS2 PE=1 SV=1 8.75 2351.5 - 516307 - - - 0.2778 - 1.03 0.009 - 105.3 3 2 0 0.0002 7 0 0 0 1.98E+07 2.45E+07 - - - -1.0121 0.9901 230117_WJC_METTL3_WT_vs_EV_F06.09246.09246.2 0.279 14-Jun R.GLDVEDVK.F "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 6 873.4444 0.95 45931 9246 2 873.445281 437.7295 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 2370.6 - 217041 - - - 1.051 - 1.183 0.128 - 97.4 1 2 0 0.0009 8 0 0 0 1.24E+07 1.30E+07 - - - 0.493 0.9799 230117_WJC_METTL3_WT_vs_EV_F06.09259.09259.2 1.87 14-Jun R.TTC[160.03]FQGVK.V "sp|Q86XD8|ZFAN4_HUMAN,tr|J3KPC0|J3KPC0_HUMAN" 2 939.4484 4.52 45933 9259 2 939.449346 470.7315 AN1-type zinc finger protein 4 OS=Homo sapiens OX=9606 GN=ZFAND4 PE=2 SV=2 7.89 2372.7 - 117928 - - - 1.0048 - 1.169 0.068 - 124.6 1 2 0 0.0009 8 0 0 0 6.64E+07 1.47E+07 - - - 0.0139 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.09288.09288.2 0.0201 14-Aug K.VIPELNGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 868.5018 3.05 45938 9288 2 868.502574 435.2582 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2377.3 - 1.17E+06 - - - 0.8705 - 1.434 0.393 - 216.4 1 2 0 0.0008 8 0 0 0 9.77E+07 3.21E+07 - - - 3.0306 0.9377 230117_WJC_METTL3_WT_vs_EV_F06.09297.09297.2 1.66 16-Apr R.QTVAVGVIK[136.11].N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 921.5739 4.55 45939 9297 2 921.574817 461.7942 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2378.8 - 275638 - - - 1.0308 - 0.93 0.131 - 42.9 15 2 0 0.0009 9 0 0 0 7.10E+07 1.56E+07 - - - -0.727 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.09299.09299.2 0.00291 16-Sep R.QTVAVGVIK.N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 913.5597 4.55 45941 9299 2 913.560965 457.7871 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2379.1 - 974007 - - - 1.4208 - 1.592 0.355 - 311.5 1 2 0 0.0013 9 0 0 0 7.10E+07 1.56E+07 - - - 3.0079 0.9405 230117_WJC_METTL3_WT_vs_EV_F06.09322.09322.2 0.103 14-Oct R.PVGVVVPR.G "sp|O75525|KHDR3_HUMAN,tr|H0YAQ3|H0YAQ3_HUMAN,tr|E5RJZ9|E5RJZ9_HUMAN,tr|H0YAQ1|H0YAQ1_HUMAN" 4 821.5123 1.14 45947 9322 2 821.513017 411.7634 "KH domain-containing, RNA-binding, signal transduction-associated protein 3 OS=Homo sapiens OX=9606 GN=KHDRBS3 PE=1 SV=1" 10.18 2382.6 - 343168 - - - 0.8448 - 1.732 0.271 - 228.5 1 1 0 0.0007 8 0 0 0 2.69E+07 2.35E+07 - - - 2.699 0.9902 230117_WJC_METTL3_WT_vs_EV_F06.09338.09338.2 6.75 12-Jun K.VVPLYGR.G "sp|Q99942|RNF5_HUMAN,tr|A0A140TA09|A0A140TA09_HUMAN" 2 802.4701 2.26 45950 9338 2 802.471747 402.2423 E3 ubiquitin-protein ligase RNF5 OS=Homo sapiens OX=9606 GN=RNF5 PE=1 SV=1 8.72 2385 - 736954 - - - 2.0225 - 1.035 0.192 - 194.5 1 2 0 0.0016 7 0 0 0 7.35E+07 3.26E+07 - - - 0.5676 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.09343.09343.2 0.00334 14-Aug R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 1.08 45952 9343 2 898.524673 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 2385.7 - 468649 - - - 1.1764 - 1.658 0.337 - 216.8 1 2 0 0.0011 8 0 0 0 5.81E+07 5.40E+07 - - - 3.0547 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.09362.09362.2 0.295 14-Sep R.LVGDVIQR[166.11].F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 908.5319 1.1 45956 9362 2 908.534169 455.2732 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 2388.6 - 995278 - - - 2.5128 - 1.559 0.193 - 251.5 1 2 0 0.0023 8 0 0 0 5.68E+07 5.17E+07 - - - 1.805 0.9014 230117_WJC_METTL3_WT_vs_EV_F06.09419.09419.2 0.0147 14-Jul R.YPDGIISK.P sp|Q86U44|MTA70_HUMAN 1 891.4702 178.78 45971 9419 2 891.471456 446.7424 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2397.2 - 807996 - - - 1.428 - 1.363 0.283 - 145.4 1 1 0 0.0013 8 0 0 0 4.19E+08 2.34E+06 - - - 2.0648 0.9479 230117_WJC_METTL3_WT_vs_EV_F06.09469.09469.2 0.102 12-Apr R.IVTTYIR[166.11].E "sp|P50570|DYN2_HUMAN,tr|K7EMQ3|K7EMQ3_HUMAN" 2 874.5152 1.44 45978 9469 2 874.51522 438.2649 Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2 8.75 2405.4 - 264775 - - - 0.0537 - 1.043 0.076 - 44.4 2 2 0 0 7 0 0 0 2.34E+07 1.62E+07 - - - -0.3987 0.9915 230117_WJC_METTL3_WT_vs_EV_F06.09477.09477.2 1.25 12-Jun K.LLEQALK.T sp|Q99543|DNJC2_HUMAN 1 813.496 1.34 45980 9477 2 813.495307 407.7553 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 6 2406.6 - 228637 - - - -0.8568 - 1.449 0.141 - 93.4 1 2 0 -0.0007 7 0 0 0 1.21E+07 9.00E+06 - - - 1.2573 0.9811 230117_WJC_METTL3_WT_vs_EV_F06.09484.09484.2 0.288 16-Jul K.TIAPALVSK.K "sp|P06733|ENOA_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y6I8|A0A2R8Y6I8_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 6 898.5488 0.26 45981 9484 2 898.548158 450.2817 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 8.41 2407.7 - 191776 - - - -0.6789 - 1.19 0.158 - 119.4 2 2 0 -0.0006 9 0 0 0 9.07E+06 3.51E+07 - - - 0.5766 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.09518.09518.2 0.000795 18-Aug R.GYSFTTTAER.E "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1131.5197 1.3 45989 9518 2 1131.518482 566.7671 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 2412.9 - 117122 - - - -1.0349 - 1.519 0.407 - 267 1 2 0 -0.0012 10 0 0 0 6.54E+06 5.03E+06 - - - 3.2136 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.09526.09526.2 0.000888 18-Aug K.FADLSEAANR.N "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1092.52 1.53 45990 9526 2 1092.520411 547.2673 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 2414.2 - 98884.5 - - - 0.3881 - 1.591 0.246 - 205.5 1 2 0 0.0004 10 0 0 0 2.70E+07 1.76E+07 - - - 2.154 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.09614.09614.2 0.00926 16-Jul R.QAVDVSPLR[166.11].R "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 993.5483 0.91 46013 9614 2 993.551105 497.7814 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 5.84 2427.5 - 171493 - - - 2.8594 - 1.449 0.296 - 133.6 1 2 0 0.0028 9 0 0 0 4.49E+06 4.93E+06 - - - 2.2993 0.9532 230117_WJC_METTL3_WT_vs_EV_F06.09638.09638.2 1.86 12-Jun K.LEPVPLK.G "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN" 2 794.4902 2.26 46015 9638 2 794.489386 398.2524 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6 2431.6 - 403748 - - - -1.0132 - 1.192 0.066 - 132.3 1 2 0 -0.0008 7 0 0 0 5.35E+07 2.36E+07 - - - 0.0847 0.9934 230117_WJC_METTL3_WT_vs_EV_F06.09645.09645.2 8.3 14-Jun R.LLTGPVVR.G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 853.5385 2.57 46018 9645 2 853.538718 427.7765 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2432.4 - 421154 - - - 0.2109 - 1.269 0.165 - 98.7 1 2 0 0.0002 8 0 0 0 3.84E+07 1.49E+07 - - - 0.9781 0.9119 230117_WJC_METTL3_WT_vs_EV_F06.09657.09657.2 4.23 12-Jun K.LEPVPLK[136.11].G "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN" 2 802.5044 2.26 46020 9657 2 802.504526 402.2595 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6 2434.3 - 754394 - - - 0.1682 - 1.036 0.045 - 148.7 4 2 0 0.0001 7 0 0 0 5.35E+07 2.36E+07 - - - -0.7836 0.9943 230117_WJC_METTL3_WT_vs_EV_F06.09668.09668.2 0.136 12-Jun R.ILVDVEK.V sp|P11216|PYGB_HUMAN 1 814.48 0.26 46024 9668 2 814.480038 408.2473 "Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB PE=1 SV=5" 4.37 2435.9 - 272370 - - - 0.0221 - 1.524 0.107 - 96.8 1 2 0 0 7 0 0 0 1.21E+07 4.71E+07 - - - 1.1663 0.9712 230117_WJC_METTL3_WT_vs_EV_F06.09685.09685.2 1.79 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 103.6 46030 9685 2 841.502278 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 2438.2 - 4.08E+06 - - - 0.1497 - 1.355 0.019 - 193 2 2 0 0.0001 8 0 0 0 7.24E+08 6.99E+06 - - - -0.0369 0.8478 230117_WJC_METTL3_WT_vs_EV_F06.09702.09702.2 10.8 12-May K.LVAQLYK.L "sp|O75390|CISY_HUMAN,tr|H0YIC4|H0YIC4_HUMAN,tr|B4DJV2|B4DJV2_HUMAN,tr|A0A0C4DGI3|A0A0C4DGI3_HUMAN" 4 833.5011 1.68 46031 9702 2 833.501848 417.7578 "Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2" 8.59 2441.2 - 237478 - - - 0.9094 - 0.988 0.003 - 75.3 6 2 0 0.0008 7 0 0 0 3.29E+07 1.96E+07 - - - -1.3229 0.9925 230117_WJC_METTL3_WT_vs_EV_F06.09716.09716.2 0.086 12-Jun R.VLSSLVR.D sp|Q969H6|POP5_HUMAN 1 772.4807 1.87 46035 9716 2 772.481594 387.2476 Ribonuclease P\MRP protein subunit POP5 OS=Homo sapiens OX=9606 GN=POP5 PE=1 SV=1 9.72 2443.2 - 596200 - - - 1.1716 - 1.251 0.126 - 164.7 1 2 0 0.0009 7 0 0 0 4.46E+07 2.38E+07 - - - 0.6809 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.09732.09732.2 0.0296 22-Aug R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 282.43 46039 9732 2 1380.643597 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2445.6 - 59122.9 - - - 1.9607 - 1.656 0.312 - 120.3 1 2 0 0.0027 12 0 0 0 7.10E+06 2.51E+04 - - - 2.6718 0.9954 230117_WJC_METTL3_WT_vs_EV_F06.09734.09734.2 0.0676 12-Jul R.LGPETFR[166.11].Q sp|P57086|SCND1_HUMAN 1 828.4369 1.78 46040 9734 2 828.436936 415.2257 SCAN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCAND1 PE=1 SV=1 6 2445.9 - 118035 - - - 0.0157 - 1.224 0.225 - 110.6 1 2 0 0 7 0 0 0 3.80E+07 2.13E+07 - - - 1.3433 0.9828 230117_WJC_METTL3_WT_vs_EV_F06.09756.09756.2 0.663 14-Jul R.ILADEALK.L sp|Q08426|ECHP_HUMAN 1 871.5015 1.2 46045 9756 2 871.503341 436.758 Peroxisomal bifunctional enzyme OS=Homo sapiens OX=9606 GN=EHHADH PE=1 SV=3 4.37 2449.2 - 307133 - - - 2.1308 - 1.126 0.109 - 90.3 1 2 0 0.0019 8 0 0 0 7.85E+06 6.52E+06 - - - 0.2034 0.9836 230117_WJC_METTL3_WT_vs_EV_F06.09759.09759.2 1.34 12-Jun K.LEATMLR[166.11].L "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 842.4559 6.4 46046 9759 2 842.456926 422.2352 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6 2449.6 - 352470 - - - 1.1656 - 1.215 0.065 - 91.9 1 2 0 0.001 7 0 0 0 1.66E+08 2.59E+07 - - - 0.1378 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.09765.09765.2 0.0128 16-Jul K.IVVVTAGVR[166.11].Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 922.5839 0.83 46049 9765 2 922.584481 462.2992 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2450.5 - 660774 - - - 0.6059 - 1.581 0.269 - 128.4 1 2 0 0.0006 9 0 0 0 1.39E+08 1.68E+08 - - - 2.3528 0.9965 230117_WJC_METTL3_WT_vs_EV_F06.09766.09766.2 0.249 12-Jul K.LEATMLR.L "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 832.4477 1.06 46050 9766 2 832.448073 417.2311 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6 2450.6 - 490854 - - - 0.4793 - 1.462 0.155 - 163.8 1 2 0 0.0004 7 0 0 0 2.28E+07 2.14E+07 - - - 1.3891 0.8922 230117_WJC_METTL3_WT_vs_EV_F06.09771.09771.2 0.347 12-Aug N.LNTLIQR[166.11].S "sp|P20036|DPA1_HUMAN,sp|Q00839|HNRPU_HUMAN,sp|Q8IUG5|MY18B_HUMAN,tr|A0A140T914|A0A140T914_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|F5H6I8|F5H6I8_HUMAN,tr|A0A140T9R4|A0A140T9R4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A140T9D6|A0A140T9D6_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A140T9Y9|A0A140T9Y9_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A140T9H1|A0A140T9H1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A140T9U4|A0A140T9U4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A140T9F8|A0A140T9F8_HUMAN,tr|J3KQ99|J3KQ99_HUMAN" 24 866.5213 0.58 46051 9771 2 866.521912 434.2679 "HLA class II histocompatibility antigen, DP alpha 1 chain OS=Homo sapiens OX=9606 GN=HLA-DPA1 PE=1 SV=1" 9.75 2451.4 - 2.58E+06 - - - 0.682 - 1.912 0.131 - 279.1 1 1 0 0.0006 7 0 0 0 9.66E+07 1.65E+08 - - - 2.0621 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.09777.09777.2 0.00377 16-Aug K.IVVVTAGVR.Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 912.5757 0.86 46053 9777 2 912.576675 457.2951 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2452.2 - 1.07E+06 - - - 1.121 - 1.62 0.328 - 215.3 1 2 0 0.001 9 0 0 0 1.45E+08 1.69E+08 - - - 2.859 0.9938 230117_WJC_METTL3_WT_vs_EV_F06.09810.09810.2 6.08 12-Jun K.ILLSPER.V "sp|P24928|RPB1_HUMAN,tr|H3BVE3|H3BVE3_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 3 826.4913 0.98 46062 9810 2 826.492024 414.2529 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 6 2457 - 533533 - - - 0.9329 - 1.285 0.136 - 124 1 2 0 0.0008 7 0 0 0 9.53E+07 9.75E+07 - - - 0.8398 0.9942 230117_WJC_METTL3_WT_vs_EV_F06.09846.09846.2 0.323 18-Jun K.MLVSGAGDIK.L "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 989.5216 19.65 46067 9846 2 989.521307 495.7681 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.59 2462.9 - 232472 - - - -0.2628 - 1.14 0.253 - 83.8 1 2 0 -0.0003 10 0 0 0 1.37E+07 6.97E+05 - - - 1.2753 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.09881.09881.2 0.332 12-Aug R.MIVGTLK.G "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 760.4517 2.78 46070 9881 2 760.451742 381.2331 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 8.5 2468.9 - 641541 - - - 0.0592 - 1.422 0.181 - 252.5 1 2 0 0 7 0 0 0 3.45E+08 1.24E+08 - - - 1.4934 0.9411 230117_WJC_METTL3_WT_vs_EV_F06.09893.09893.2 4.17 12-Jun R.MIVGTLK[136.11].G "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 768.4659 2.77 46072 9893 2 768.466413 385.2402 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 8.5 2470.7 - 944888 - - - 0.6715 - 0.955 0.081 - 122.3 2 2 0 0.0005 7 0 0 0 3.46E+08 1.25E+08 - - - -0.6413 0.9843 230117_WJC_METTL3_WT_vs_EV_F06.09897.09897.2 1.84 12-Jun R.ILLEAAR[166.11].L "sp|P49189|AL9A1_HUMAN,sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 3 794.489 2.17 46073 9897 2 794.488291 398.2518 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3 6 2471.3 - 484586 - - - -0.8408 - 1.392 0.094 - 115.7 1 2 0 -0.0007 7 0 0 0 6.64E+07 3.06E+07 - - - 0.783 0.9782 230117_WJC_METTL3_WT_vs_EV_F06.09914.09914.2 8.98 12-Jun R.ILLEAAR.L "sp|P49189|AL9A1_HUMAN,sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 3 784.4807 2.16 46079 9914 2 784.480568 393.2476 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3 6 2473.7 - 1.69E+06 - - - -0.1542 - 1.253 0.086 - 90.1 2 2 0 -0.0001 7 0 0 0 6.73E+07 3.11E+07 - - - 0.2563 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.09951.09951.2 0.0123 16-Aug R.SLVNLGGSK.S sp|P04264|K2C1_HUMAN 1 873.492 44.17 46086 9951 2 873.491549 437.7533 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.47 2479.5 - 927814 - - - -0.4957 - 1.406 0.42 - 203.7 1 2 0 -0.0004 9 0 0 0 5.19E+07 1.18E+06 - - - 3.1288 1 230117_WJC_METTL3_WT_vs_EV_F06.09998.09998.2 2.57E-07 22-Dec R.AQVQEFC[160.03]DYGTK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1444.6293 11.03 46095 9998 2 1444.631468 723.3219 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2486.8 - 454382 - - - 1.5146 - 2.267 0.656 - 460.1 1 2 0 0.0022 12 0 0 0 2.33E+07 2.12E+06 - - - 6.039 0.8563 230117_WJC_METTL3_WT_vs_EV_F06.10002.10002.2 0.0585 12-Jul G.IIEPSLR.Q "sp|P62987|RL40_HUMAN,tr|M0R1A4|M0R1A4_HUMAN,tr|M0QZ32|M0QZ32_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|M0R1M6|M0R1M6_HUMAN" 5 826.4913 1.23 46097 10002 2 826.491767 414.2529 Ubiquitin-60S ribosomal protein L40 OS=Homo sapiens OX=9606 GN=UBA52 PE=1 SV=2 6 2487.2 - 8.15E+06 - - - 0.6219 - 1.679 0.148 - 187.5 1 1 0 0.0005 7 0 0 0 8.33E+08 6.80E+08 - - - 1.7759 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.10003.10003.2 0.000293 22-Jun R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 11.03 46098 10003 2 1452.643302 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2487.4 - 58018.7 - - - -0.1225 - 1.659 0.555 - 104.4 1 2 0 -0.0002 12 0 0 0 2.33E+07 2.12E+06 - - - 4.4721 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.10004.10004.2 0.947 16-Jul R.GPLVNASLR[166.11].A "sp|O14744|ANM5_HUMAN,tr|H0YJ77|H0YJ77_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 3 935.5428 0.45 46099 10004 2 935.543747 468.7787 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 9.75 2487.5 - 122791 - - - 1.0283 - 1.468 0.145 - 100.4 1 2 0 0.001 9 0 0 0 2.78E+06 6.14E+06 - - - 1.2223 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.10024.10024.2 0.0672 14-Aug R.VMGLVPAK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 821.4924 1.72 46106 10024 2 821.493087 411.7535 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.72 2490.5 - 324227 - - - 0.7803 - 1.332 0.28 - 161.2 1 2 0 0.0006 8 0 0 0 3.89E+07 2.26E+07 - - - 1.9735 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.10039.10039.2 0.0122 12-Jul R.LMDVMAK.E sp|Q12874|SF3A3_HUMAN 1 806.403 3.18 46110 10039 2 806.403388 404.2088 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2492.7 - 535655 - - - 0.4415 - 1.428 0.29 - 162.1 1 2 0 0.0004 7 0 0 0 1.28E+08 4.03E+07 - - - 2.3117 0.9948 230117_WJC_METTL3_WT_vs_EV_F06.10056.10056.2 0.0703 12-Apr R.LMDVMAK[136.11].E sp|Q12874|SF3A3_HUMAN 1 814.4172 3.19 46111 10056 2 814.417766 408.2159 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2495.7 - 671274 - - - 0.6557 - 1.069 0.309 - 44.6 14 2 0 0.0005 7 0 0 0 1.27E+08 3.98E+07 - - - 1.0225 0.9731 230117_WJC_METTL3_WT_vs_EV_F06.10087.10087.2 0.316 12-Jun -.MAAPILR.S sp|Q9Y2Z4|SYYM_HUMAN 1 770.4473 4.09 46116 10087 2 770.446875 386.2309 "Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2" 9.5 2500.8 - 1.46E+06 - - - -0.5257 - 1.285 0.076 - 130.5 2 2 0 -0.0004 7 0 0 0 1.44E+08 3.51E+07 - - - 0.2623 0.9918 230117_WJC_METTL3_WT_vs_EV_F06.10109.10109.2 1.02 14-Sep R.IIAEALTR.V "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 5 885.5284 0.99 46119 10109 2 885.529987 443.7715 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 2504.5 - 742096 - - - 1.8294 - 1.362 0.092 - 229.5 1 2 0 0.0016 8 0 0 0 5.13E+07 5.16E+07 - - - 0.6518 0.9836 230117_WJC_METTL3_WT_vs_EV_F06.10113.10113.2 3.18 14-Jun R.IIAEALTR[166.11].V "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 5 895.5366 0.99 46120 10113 2 895.53831 448.7756 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 2505.1 - 815150 - - - 1.8682 - 1.134 0.103 - 89.6 1 2 0 0.0017 8 0 0 0 5.13E+07 5.16E+07 - - - 0.1805 0.9865 230117_WJC_METTL3_WT_vs_EV_F06.10149.10149.2 0.534 16-May K.VELQELNDR.F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1114.5619 4.63 46125 10149 2 1114.565647 558.2882 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.14 2511.1 - 252979 - - - 3.4049 - 1.387 0.156 - 93.4 4 2 0 0.0038 9 0 0 0 2.75E+07 5.93E+06 - - - 0.8695 0.9781 230117_WJC_METTL3_WT_vs_EV_F06.10157.10157.2 2.85 12-Jul R.VLYSLAK[136.11].K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 800.4887 1.38 46128 10157 2 800.488951 401.2516 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.56 2512.2 - 569772 - - - 0.2623 - 1.216 0.061 - 196.7 1 2 0 0.0002 7 0 0 0 6.26E+07 4.54E+07 - - - 0.1111 0.9946 230117_WJC_METTL3_WT_vs_EV_F06.10164.10164.2 1.41 12-Jun R.VLYSLAK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 792.4745 1.3 46130 10164 2 792.47471 397.2445 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.56 2513.2 - 654046 - - - 0.2133 - 1.412 0.135 - 128.4 1 2 0 0.0002 7 0 0 0 5.86E+07 4.50E+07 - - - 1.1312 0.9576 230117_WJC_METTL3_WT_vs_EV_F06.10210.10210.2 4.95 12-Jun R.LYTVVPR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 846.4963 1.52 46138 10210 2 846.496633 424.2554 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 2520.4 - 1.59E+06 - - - 0.3473 - 1.041 0.065 - 118.8 1 2 0 0.0003 7 0 0 0 1.53E+08 1.01E+08 - - - -0.3517 0.9233 230117_WJC_METTL3_WT_vs_EV_F06.10224.10224.2 10.2 14-Jun R.AVAPGLVR[166.11].Y "sp|Q9BSI4|TINF2_HUMAN,tr|H0YMN3|H0YMN3_HUMAN,tr|H0YL20|H0YL20_HUMAN,tr|H0YLC9|H0YLC9_HUMAN,tr|B4DFJ1|B4DFJ1_HUMAN" 5 791.4893 2.28 46141 10224 2 791.489779 396.7519 TERF1-interacting nuclear factor 2 OS=Homo sapiens OX=9606 GN=TINF2 PE=1 SV=1 9.79 2522.5 - 305105 - - - 0.614 - 1.088 0.029 - 74.3 5 2 0 0.0005 8 0 0 0 2.20E+07 9.62E+06 - - - -0.8028 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.10250.10250.2 0.0199 12-Jun R.LYTVVPR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 856.5046 1.52 46148 10250 2 856.505977 429.2596 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 2526.4 - 1.38E+06 - - - 1.5972 - 1.249 0.239 - 144.2 1 2 0 0.0014 7 0 0 0 1.53E+08 1.01E+08 - - - 1.5103 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.10251.10251.2 0.0416 14-Sep K.IPAMTIAK[136.11].N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.503 2.15 46149 10251 2 851.503798 426.7588 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2526.5 - 1.40E+06 - - - 0.9254 - 1.518 0.219 - 234.2 1 2 0 0.0008 8 0 0 0 2.09E+09 9.69E+08 - - - 1.9171 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.10255.10255.2 0.0933 14-Aug K.IPAMTIAK.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.4888 2.15 46151 10255 2 843.489541 422.7517 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2527 - 3.40E+06 - - - 0.8666 - 1.329 0.282 - 172.2 1 2 0 0.0007 8 0 0 0 2.09E+09 9.69E+08 - - - 1.9814 0.996 230117_WJC_METTL3_WT_vs_EV_F06.10274.10274.2 0.00139 16-Jun R.VLPVYGGPK.G "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 928.5382 1.53 46156 10274 2 928.53707 465.2764 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 8.56 2529.8 - 192651 - - - -1.2202 - 1.359 0.298 - 86.7 1 2 0 -0.0011 9 0 0 0 1.89E+07 1.24E+07 - - - 2.1291 0.9935 230117_WJC_METTL3_WT_vs_EV_F06.10312.10312.2 0.536 12-Jul R.VAPVLIR.E "sp|P30419|NMT1_HUMAN,sp|O60551|NMT2_HUMAN,tr|A0A7I2V3X4|A0A7I2V3X4_HUMAN,tr|A0A7I2V539|A0A7I2V539_HUMAN,tr|Q5VUC6|Q5VUC6_HUMAN,tr|A0A7I2V3U5|A0A7I2V3U5_HUMAN" 6 766.5065 0.74 46165 10312 2 766.505905 384.2605 Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2 9.72 2535.4 - 903525 - - - -0.788 - 1.453 0.165 - 260.3 1 2 0 -0.0006 7 0 0 0 2.98E+07 4.00E+07 - - - 1.4434 0.9744 230117_WJC_METTL3_WT_vs_EV_F06.10319.10319.2 0.283 14-Jul R.LLTGPVVR[166.11].G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 863.5468 2.08 46166 10319 2 863.544763 432.7807 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2536.5 - 3.23E+06 - - - -2.3681 - 1.301 0.177 - 124 1 2 0 -0.002 8 0 0 0 2.92E+08 1.41E+08 - - - 1.1413 0.9761 230117_WJC_METTL3_WT_vs_EV_F06.10377.10377.2 0.0627 16-Oct K.LSDGVAVLK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 908.5422 2.76 46170 10377 2 908.53745 455.2784 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2546 - 3.23E+06 - - - -5.2645 - 1.831 0.292 - 185.5 1 2 0 -0.0048 9 0 0 0 2.16E+08 7.82E+07 - - - 2.9461 0.9659 230117_WJC_METTL3_WT_vs_EV_F06.10416.10416.2 0.848 12-Jul R.LLAALER[166.11].R sp|Q96A98|TIP39_HUMAN 1 794.489 1.28 46171 10416 2 794.487138 398.2518 Tuberoinfundibular peptide of 39 residues OS=Homo sapiens OX=9606 GN=PTH2 PE=1 SV=1 6 2552.7 - 1.37E+07 - - - -2.292 - 1.605 0.075 - 153.1 3 2 0 -0.0018 7 0 0 0 1.37E+09 1.06E+09 - - - 0.8804 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.10420.10420.2 0.000217 12-Jul R.LVDMMER.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 892.4147 1.15 46172 10420 2 892.413693 447.2146 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 2553.3 - 1.41E+06 - - - -1.0825 - 1.288 0.507 - 170.8 1 2 0 -0.001 7 0 0 0 1.75E+08 1.52E+08 - - - 3.5873 0.8727 230117_WJC_METTL3_WT_vs_EV_F06.10462.10462.2 0.0194 14-Sep K.PSPLLVGR.E "sp|Q13283|G3BP1_HUMAN,sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2R0|A0A7I2V2R0_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RGJ4|D6RGJ4_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|D6R9A4|D6R9A4_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|E5RI46|E5RI46_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 25 837.5072 1.52 46176 10462 2 837.50648 419.7609 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 10.18 2560 - 1.72E+06 - - - -0.9051 - 1.596 0.312 - 332.9 1 1 0 -0.0008 8 0 0 0 1.32E+08 8.70E+07 - - - 2.7552 0.9914 230117_WJC_METTL3_WT_vs_EV_F06.10486.10486.2 0.509 12-Jul K.FIGELGK.L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 762.4276 2.05 46177 10486 2 762.425849 382.2211 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2564.1 - 2.10E+06 - - - -2.2835 - 1.442 0.249 - 182.6 1 2 0 -0.0017 7 0 0 0 2.36E+08 1.15E+08 - - - 2.0394 0.9683 230117_WJC_METTL3_WT_vs_EV_F06.10499.10499.2 0.196 12-Jun K.FIGELGK[136.11].L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 770.4418 1.99 46180 10499 2 770.438208 386.2282 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2565.9 - 1.11E+06 - - - -4.6493 - 1.43 0.273 - 147.7 1 2 0 -0.0036 7 0 0 0 2.29E+08 1.15E+08 - - - 2.1896 0.9694 230117_WJC_METTL3_WT_vs_EV_F06.10523.10523.2 0.424 14-Jun R.VVLLAEGR.L sp|O43865|SAHH2_HUMAN 1 855.5178 4.86 46185 10523 2 855.515103 428.7662 S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1 PE=1 SV=2 5.97 2569.4 - 1.25E+06 - - - -3.1548 - 1.207 0.241 - 95.8 1 2 0 -0.0027 8 0 0 0 4.13E+07 8.50E+06 - - - 1.3876 0.9929 230117_WJC_METTL3_WT_vs_EV_F06.10535.10535.2 0.0366 14-Aug R.LGPLQVAR.V sp|P38117|ETFB_HUMAN 1 852.5181 3.7 46187 10535 2 852.515462 427.2663 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 9.75 2571.3 - 3.28E+06 - - - -3.1378 - 1.757 0.282 - 277.7 1 2 0 -0.0027 8 0 0 0 2.46E+08 6.66E+07 - - - 2.8228 0.9787 230117_WJC_METTL3_WT_vs_EV_F06.10555.10555.2 0.118 12-Jul K.AIFAGYK.R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 768.417 0.78 46191 10555 2 768.4163 385.2158 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2574.3 - 1.23E+06 - - - -0.9448 - 1.206 0.132 - 143.2 1 2 0 -0.0007 7 0 0 0 2.56E+08 3.27E+08 - - - 0.6092 0.9921 230117_WJC_METTL3_WT_vs_EV_F06.10570.10570.2 0.181 12-Jun K.AIFAGYK[136.11].R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 776.4312 0.78 46195 10570 2 776.430783 389.2229 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2576.5 - 4.53E+06 - - - -0.5706 - 1.221 0.203 - 158 1 2 0 -0.0004 7 0 0 0 2.56E+08 3.27E+08 - - - 1.1729 0.9596 230117_WJC_METTL3_WT_vs_EV_F06.10578.10578.2 0.656 14-Aug K.SVLAGPLR[166.11].T sp|Q9UBZ4|APEX2_HUMAN 1 821.4999 1 46199 10578 2 821.496511 411.7572 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 9.47 2577.5 - 890930 - - - -4.0743 - 1.413 0.209 - 216.1 1 2 0 -0.0033 8 0 0 0 3.13E+07 3.12E+07 - - - 1.6263 0.9139 230117_WJC_METTL3_WT_vs_EV_F06.10590.10590.2 3.52 12-May R.FLAPYGR.Q "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 822.4388 0.3 46201 10590 2 822.439467 412.2267 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 8.75 2579.4 - 468358 - - - 0.7818 - 0.936 0.035 - 94.8 1 2 0 0.0006 7 0 0 0 6.52E+07 2.15E+08 - - - -0.9103 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.10621.10621.2 0.00175 16-Oct R.QEYEQLIAK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1120.5764 0.58 46207 10621 2 1120.579562 561.2955 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.53 2584 - 123349 - - - 2.7861 - 1.882 0.435 - 373 1 2 0 0.0031 9 0 0 0 1.52E+07 2.60E+07 - - - 4.0823 0.9917 230117_WJC_METTL3_WT_vs_EV_F06.10633.10633.2 0.118 12-Jun K.VLLAEYK.N sp|Q16513|PKN2_HUMAN 1 834.4851 0 46209 10633 2 834.485162 418.2498 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 5.97 2585.9 - 1.15E+06 - - - 0.0683 - 1.264 0.146 - 128.1 1 2 0 0.0001 7 0 0 0 6.26E+07 2.16E+10 - - - 0.8617 0.9929 230117_WJC_METTL3_WT_vs_EV_F06.10636.10636.2 0.189 12-Jul R.FLAPYGR[166.11].Q "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 832.4471 0.3 46210 10636 2 832.446886 417.2308 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 8.75 2586.3 - 1.01E+06 - - - -0.2499 - 1.221 0.194 - 180 1 2 0 -0.0002 7 0 0 0 6.55E+07 2.16E+08 - - - 1.1065 0.9946 230117_WJC_METTL3_WT_vs_EV_F06.10639.10639.2 0.157 12-Jul R.LPPDVLR.W sp|P78527|PRKDC_HUMAN 1 808.4807 16.94 46211 10639 2 808.480789 405.2476 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2586.7 - 817031 - - - 0.1237 - 1.343 0.16 - 185.5 1 2 0 0.0001 7 0 0 0 1.06E+09 6.24E+07 - - - 1.1572 0.9921 230117_WJC_METTL3_WT_vs_EV_F06.10640.10640.2 0.471 14-Jul K.LLEATELK[136.11].G "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 923.5419 1.13 46212 10640 2 923.543195 462.7782 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 2586.8 - 942842 - - - 1.4044 - 1.355 0.092 - 111.1 1 2 0 0.0013 8 0 0 0 4.08E+07 3.61E+07 - - - 0.6364 0.9908 230117_WJC_METTL3_WT_vs_EV_F06.10643.10643.2 0.235 12-Jun R.VLISSLK.D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 758.4902 0.88 46213 10643 2 758.491528 380.2524 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2587.2 - 202222 - - - 1.7627 - 1.319 0.087 - 89.7 1 2 0 0.0013 7 0 0 0 9.76E+07 1.11E+08 - - - 0.5605 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.10648.10648.2 0.0376 14-Aug K.LLEATELK.G "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 915.5277 1.13 46216 10648 2 915.527363 458.7711 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 2587.9 - 1.17E+06 - - - -0.3659 - 1.466 0.274 - 181.8 1 2 0 -0.0003 8 0 0 0 4.08E+07 3.61E+07 - - - 2.2184 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.10654.10654.2 0.00628 14-Jul K.YVPLADVK[136.11].S "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 911.5208 0.83 46220 10654 2 911.521371 456.7677 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.83 2588.5 - 1.13E+06 - - - 0.6604 - 1.335 0.329 - 188.7 1 2 0 0.0006 8 0 0 0 5.55E+07 6.70E+07 - - - 2.3422 0.9908 230117_WJC_METTL3_WT_vs_EV_F06.10658.10658.2 3.17 12-Jun R.VLISSLK[136.11].D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 766.5044 1.21 46221 10658 2 766.505151 384.2595 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2589.1 - 671137 - - - 0.9915 - 1.228 0.116 - 133.2 1 2 0 0.0008 7 0 0 0 9.62E+07 7.94E+07 - - - 0.5483 0.9379 230117_WJC_METTL3_WT_vs_EV_F06.10660.10660.2 2.46 12-May K.SVLTPLR[166.11].G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 794.489 1.35 46222 10660 2 794.488537 398.2518 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2589.3 - 515072 - - - -0.5312 - 1.158 0.055 - 83.2 3 2 0 -0.0004 7 0 0 0 5.74E+07 4.24E+07 - - - -0.3012 0.9899 230117_WJC_METTL3_WT_vs_EV_F06.10673.10673.2 0.139 14-Jun K.YVPLADVK.S "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 903.5066 0.83 46226 10673 2 903.505517 452.7606 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.83 2591.2 - 1.95E+06 - - - -1.1644 - 1.15 0.246 - 120.6 1 2 0 -0.0011 8 0 0 0 5.55E+07 6.69E+07 - - - 1.2791 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.10715.10715.2 1.43 12-Sep R.IVEGILK.R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 770.4902 2.09 46241 10715 2 770.49062 386.2524 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 2597.1 - 1.36E+06 - - - 0.5568 - 1.617 0.138 - 196.7 1 2 0 0.0004 7 0 0 0 7.43E+08 3.55E+08 - - - 1.5829 0.9861 230117_WJC_METTL3_WT_vs_EV_F06.10716.10716.2 1.83 12-May R.IVEGILK[136.11].R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 778.5044 2.09 46242 10716 2 778.505194 390.2595 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 2597.2 - 893454 - - - 1.0315 - 1.162 0.155 - 45.8 8 2 0 0.0008 7 0 0 0 7.43E+08 3.55E+08 - - - 0.2579 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.10721.10721.2 0.0543 12-Jul K.MGITPLR.N "sp|Q12789|TF3C1_HUMAN,sp|O43325|LYRM1_HUMAN,tr|H3BNA8|H3BNA8_HUMAN" 3 786.4422 1.25 46243 10721 2 786.442881 394.2284 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 9.5 2598 - 575784 - - - 0.8723 - 1.465 0.241 - 176.9 1 2 0 0.0007 7 0 0 0 5.58E+07 4.46E+07 - - - 2.0307 1 230117_WJC_METTL3_WT_vs_EV_F06.10733.10733.2 0.000496 26-Nov R.SLYASSPGGVYATR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1427.7045 1.89 46248 10733 2 1427.705763 714.8595 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2599.6 - 91046.3 - - - 0.8888 - 2.231 0.546 - 350.1 1 2 0 0.0013 14 0 0 0 8.54E+06 4.52E+06 - - - 5.0871 0.9871 230117_WJC_METTL3_WT_vs_EV_F06.10742.10742.2 0.871 12-Jun K.VVLQELR[166.11].R "sp|Q13404|UB2V1_HUMAN,sp|Q15819|UB2V2_HUMAN,sp|Q8NGI1|O56B2_HUMAN,tr|G3V2F7|G3V2F7_HUMAN,tr|A0A0A0MSL3|A0A0A0MSL3_HUMAN,tr|G3V113|G3V113_HUMAN,tr|H0YBP9|H0YBP9_HUMAN,tr|I3L0A0|I3L0A0_HUMAN" 8 865.5261 1.49 46250 10742 2 865.529924 433.7703 Ubiquitin-conjugating enzyme E2 variant 1 OS=Homo sapiens OX=9606 GN=UBE2V1 PE=1 SV=2 5.97 2601 - 361772 - - - 4.4505 - 1.428 0.174 - 137.5 1 2 0 0.0039 7 0 0 0 1.55E+07 1.03E+07 - - - 1.4538 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.10745.10745.2 0.0116 18-Aug R.IITEGFEAAK.E sp|P40227|TCPZ_HUMAN 1 1077.5706 11.96 46252 10745 2 1077.572895 539.7926 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 2601.4 - 272948 - - - 2.1057 - 1.41 0.314 - 135.9 1 2 0 0.0023 10 0 0 0 4.03E+07 3.37E+06 - - - 2.3186 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.10754.10754.2 0.0295 12-Aug K.LTGMAFR.V "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 794.4109 2.73 46256 10754 2 794.412009 398.2127 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 9.75 2602.6 - 2.95E+06 - - - 1.4036 - 1.806 0.325 - 210.8 1 2 0 0.0011 7 0 0 0 1.21E+10 4.43E+09 - - - 3.3141 0.916 230117_WJC_METTL3_WT_vs_EV_F06.10779.10779.2 1.63 16-Jun R.EVEMDAVGK.D sp|P31327|CPSM_HUMAN 1 976.4535 999 46263 10779 2 976.453056 489.234 "Carbamoyl-phosphate synthase [ammonia], mitochondrial OS=Homo sapiens OX=9606 GN=CPS1 PE=1 SV=2" 4.14 2606.4 - 182979 - - - -0.5028 - 0.799 0.148 - 105.8 1 2 0 -0.0005 9 0 0 0 8.23E+06 0.00E+00 - - - -0.5152 0.9948 230117_WJC_METTL3_WT_vs_EV_F06.10796.10796.2 3.04 12-Aug R.MGLVMDR[166.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 830.4018 2.22 46269 10796 2 830.400896 416.2082 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2608.6 - 529068 - - - -1.0886 - 1.666 0.155 - 317.7 1 2 0 -0.0009 7 0 0 0 1.22E+09 5.49E+08 - - - 1.8029 0.9933 230117_WJC_METTL3_WT_vs_EV_F06.10801.10801.2 3.07 12-Jun R.LIITQVR.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 841.5385 0.99 46271 10801 2 841.538415 421.7765 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 9.75 2609.3 - 5.83E+06 - - - -0.1462 - 1.359 0.148 - 138.5 1 2 0 -0.0001 7 0 0 0 4.21E+08 4.25E+08 - - - 1.106 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.10810.10810.2 0.0141 12-Jul R.MGLVMDR.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 820.3935 2.22 46273 10810 2 820.392416 411.204 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2610.6 - 2.55E+06 - - - -1.3579 - 1.568 0.283 - 206 1 2 0 -0.0011 7 0 0 0 1.22E+09 5.49E+08 - - - 2.5561 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.10811.10811.2 0.00131 16-Aug K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 0.8 46274 10811 2 993.583303 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2610.7 - 311401 - - - -1.3557 - 1.608 0.367 - 189.2 1 2 0 -0.0013 9 0 0 0 7.24E+07 9.08E+07 - - - 3.1254 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.10822.10822.2 0.000171 20-Aug K.FGDPVVQSDMK.H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1221.57 0.36 46278 10822 2 1221.568792 611.7923 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.21 2612.1 - 340060 - - - -0.9676 - 1.399 0.364 - 152 1 2 0 -0.0012 11 0 0 0 1.30E+07 3.59E+07 - - - 2.6374 0.9606 230117_WJC_METTL3_WT_vs_EV_F06.10837.10837.2 0.00331 16-Nov R.PGPLLVSAR[166.11].R sp|Q9NUL7|DDX28_HUMAN 1 918.5526 56.82 46282 10837 2 918.554799 460.2836 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 10.18 2614.2 - 1.04E+06 - - - 2.3711 - 1.892 0.363 - 350 1 1 0 0.0022 9 0 0 0 3.97E+09 6.99E+07 - - - 3.5661 1 230117_WJC_METTL3_WT_vs_EV_F06.10845.10845.2 2.84E-07 22-Sep R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 46284 10845 2 1474.779393 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2615.5 - 384697 - - - 0.9493 - 2.025 0.574 - 192.2 1 2 0 0.0014 12 0 0 0 3.14E+07 0.00E+00 - - - 5.1366 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.10856.10856.2 0.000402 16-Sep K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 0.8 46287 10856 2 983.576158 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2617 - 801912 - - - -0.2257 - 2.004 0.414 - 354.3 1 2 0 -0.0002 9 0 0 0 7.24E+07 9.07E+07 - - - 4.1098 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.10862.10862.2 0.00042 20-Sep K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 10229.2 46288 10862 2 1106.545609 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2617.9 - 273554 - - - -0.7166 - 1.875 0.454 - 161.5 1 2 0 -0.0008 11 0 0 0 2.01E+09 1.97E+05 - - - 4.0945 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.10877.10877.2 0.00374 14-Aug R.NGYGFINR.N "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 4 939.4563 0.3 46294 10877 2 939.455663 470.7354 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 8.75 2620 - 304941 - - - -0.6408 - 1.637 0.396 - 131.5 1 2 0 -0.0006 8 0 0 0 7.96E+06 2.66E+07 - - - 3.4521 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.10880.10880.2 0.00552 16-Aug K.EIAEAYLGK.T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 992.5179 11.21 46295 10880 2 992.51852 497.2662 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 2620.5 - 1.46E+06 - - - 0.663 - 1.355 0.285 - 241.1 1 2 0 0.0007 9 0 0 0 6.19E+07 5.52E+06 - - - 2.0247 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.10885.10885.2 0.185 12-Jun R.LILPEAK.V "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN,tr|A8MSZ8|A8MSZ8_HUMAN" 3 782.4902 1.46 46297 10885 2 782.490318 392.2524 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 6 2621.1 - 608722 - - - 0.1623 - 1.271 0.251 - 119.2 1 2 0 0.0001 7 0 0 0 1.06E+08 7.23E+07 - - - 1.6547 0.945 230117_WJC_METTL3_WT_vs_EV_F06.10900.10900.2 3.09 14-Jul K.EVDIYTVK[136.11].V "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 3 973.5212 0.55 46300 10900 2 973.520387 487.7679 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 2623.5 - 138303 - - - -0.7971 - 1.088 0.08 - 140.2 1 2 0 -0.0008 8 0 0 0 6.79E+06 1.24E+07 - - - -0.114 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.10909.10909.2 0.0036 14-Sep R.VITALVER.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 899.544 0.36 46302 10909 2 899.544897 450.7793 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2624.9 - 1.54E+06 - - - 0.9783 - 1.817 0.324 - 304.2 1 2 0 0.0009 8 0 0 0 2.91E+09 8.16E+09 - - - 3.2349 0.9929 230117_WJC_METTL3_WT_vs_EV_F06.10912.10912.2 0.626 12-Jun R.LPPDVLR.W sp|P78527|PRKDC_HUMAN 1 808.4807 1 46303 10912 2 808.48249 405.2476 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2625.3 - 489366 - - - 2.2276 - 1.265 0.145 - 139 1 2 0 0.0018 7 0 0 0 4.07E+07 4.05E+07 - - - 0.8562 0.987 230117_WJC_METTL3_WT_vs_EV_F06.10919.10919.2 2.22 12-Jun R.LILPEAK[136.11].V "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN,tr|A8MSZ8|A8MSZ8_HUMAN" 3 790.5044 1.52 46306 10919 2 790.504637 396.2595 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 6 2626.1 - 1.27E+06 - - - 0.3112 - 1.15 0.149 - 95.4 2 2 0 0.0002 7 0 0 0 1.06E+08 6.94E+07 - - - 0.4498 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.10935.10935.2 0.69 12-Sep R.LNELLVK.A "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L253|I3L253_HUMAN" 3 827.5117 2.15 46313 10935 2 827.511454 414.7631 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2628.3 - 429579 - - - -0.2417 - 1.789 0.137 - 240.5 1 2 0 -0.0002 7 0 0 0 5.48E+08 2.55E+08 - - - 1.8958 0.8791 230117_WJC_METTL3_WT_vs_EV_F06.10940.10940.2 1.15 14-May R.LPLETAYR[166.11].R "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 971.5316 12.5 46314 10940 2 971.532146 486.7731 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 6 2629 - 186989 - - - 0.6114 - 0.944 0.066 - 63.6 11 2 0 0.0006 8 0 0 0 4.82E+07 3.86E+06 - - - -1.1107 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.10945.10945.2 6.2 12-Jul R.LNELLVK[136.11].A "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L253|I3L253_HUMAN" 3 835.5259 2.12 46315 10945 2 835.526605 418.7702 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2629.8 - 768338 - - - 0.8988 - 1.626 0.125 - 109.8 1 2 0 0.0008 7 0 0 0 5.49E+08 2.60E+08 - - - 1.5043 0.9618 230117_WJC_METTL3_WT_vs_EV_F06.10948.10948.2 2.53 14-Jun R.LLVVTDPR[166.11].A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 921.5523 2.6 46318 10948 2 921.552045 461.7834 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.84 2630.1 - 456252 - - - -0.2626 - 1.056 0.115 - 95.8 2 2 0 -0.0002 8 0 0 0 1.47E+09 5.63E+08 - - - -0.0798 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.10952.10952.2 0.012 12-Jul K.AC[160.03]TILLR.G "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 845.4793 18.59 46320 10952 2 845.479461 423.7469 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 8.29 2630.7 - 6.20E+06 - - - 0.1798 - 1.433 0.333 - 363.3 1 2 0 0.0002 7 0 0 0 4.48E+08 2.41E+07 - - - 2.6404 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.10953.10953.2 0.00966 14-Aug R.VFVNPSLR[166.11].V sp|Q9HBH1|DEFM_HUMAN 1 940.537 1.05 46321 10953 2 940.536863 471.2758 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 9.72 2630.7 - 6.87E+06 - - - -0.1148 - 1.314 0.268 - 228.3 1 2 0 -0.0001 8 0 0 0 3.58E+08 3.42E+08 - - - 1.844 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.10970.10970.2 0.00267 14-Aug R.VFVNPSLR.V sp|Q9HBH1|DEFM_HUMAN 1 930.5287 1.05 46327 10970 2 930.52832 466.2716 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 9.72 2633 - 7.47E+06 - - - -0.4094 - 1.758 0.38 - 249.5 1 2 0 -0.0004 8 0 0 0 3.60E+08 3.42E+08 - - - 3.5491 0.9958 230117_WJC_METTL3_WT_vs_EV_F06.11002.11002.2 0.00804 14-Jul R.AIVPLEAR.M "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 867.5178 2.06 46339 11002 2 867.52012 434.7662 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 6.05 2637.4 - 320751 - - - 2.672 - 1.47 0.168 - 174.9 1 2 0 0.0023 8 0 0 0 1.08E+08 5.24E+07 - - - 1.4431 0.9639 230117_WJC_METTL3_WT_vs_EV_F06.11005.11005.2 3.4 14-Jul K.ILPVGGIK[136.11].E "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN,tr|K7ERR6|K7ERR6_HUMAN" 4 803.536 1.29 46340 11005 2 803.536938 402.7753 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 8.75 2637.8 - 639765 - - - 1.1362 - 1.021 0.07 - 111 1 2 0 0.0009 8 0 0 0 4.83E+07 3.74E+07 - - - -0.3796 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.11013.11013.2 0.226 14-Sep R.AIVPLEAR[166.11].M "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 877.5261 2.09 46344 11013 2 877.527408 439.7703 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 6.05 2638.8 - 509793 - - - 1.5225 - 1.495 0.139 - 395.4 1 2 0 0.0013 8 0 0 0 1.08E+08 5.16E+07 - - - 1.28 0.9496 230117_WJC_METTL3_WT_vs_EV_F06.11015.11015.2 7.4 12-Jun R.ILASEIR.S "sp|Q8N1K5|THMS1_HUMAN,tr|X1WI26|X1WI26_HUMAN,tr|A0A0D9SFD2|A0A0D9SFD2_HUMAN,tr|A0A0G2JQP7|A0A0G2JQP7_HUMAN" 4 800.4756 4.83 46346 11015 2 800.477913 401.2451 Protein THEMIS OS=Homo sapiens OX=9606 GN=THEMIS PE=1 SV=3 6 2639.1 - 862936 - - - 2.8858 - 1.306 0.016 - 104.1 4 2 0 0.0023 7 0 0 0 1.97E+08 4.07E+07 - - - -0.2646 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.11018.11018.2 0.328 14-Jun R.VITALVER[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 909.5523 0.36 46347 11018 2 909.553427 455.7834 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2639.4 - 2.76E+07 - - - 1.2534 - 1.501 0.23 - 116.8 1 2 0 0.0011 8 0 0 0 2.90E+09 8.16E+09 - - - 1.9643 0.8949 230117_WJC_METTL3_WT_vs_EV_F06.11023.11023.2 12.3 18-May K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 1.64 46350 11023 2 1008.597621 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2640.1 - 210959 - - - 0.8328 - 0.984 0.03 - 59.7 4 2 0 0.0008 10 0 0 0 1.69E+07 1.03E+07 - - - -1.0516 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.11026.11026.2 0.000702 22-Oct K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 2.32 46351 11026 2 1222.668277 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2640.5 - 253291 - - - 2.789 - 1.971 0.421 - 269 1 2 0 0.0034 12 0 0 0 1.00E+08 4.33E+07 - - - 3.9348 1 230117_WJC_METTL3_WT_vs_EV_F06.11029.11029.2 2.65E-07 13/22 K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 2.31 46353 11029 2 1214.65298 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2640.9 - 558836 - - - 1.9043 - 2.487 0.455 - 577.3 1 2 0 0.0023 12 0 0 0 1.00E+08 4.35E+07 - - - 4.7981 0.942 230117_WJC_METTL3_WT_vs_EV_F06.11030.11030.2 0.00519 14-Aug Q.VLVLAPTR[166.11].E "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 877.5625 0.9 46354 11030 2 877.563931 439.7885 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.72 2641 - 612031 - - - 1.6785 - 1.472 0.337 - 271 1 1 0 0.0015 8 0 0 0 1.29E+08 1.43E+08 - - - 2.6957 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.11051.11051.2 0.275 14-Aug R.ILMAINGK[136.11].V sp|O00264|PGRC1_HUMAN 1 866.5139 0.9 46359 11051 2 866.514812 434.2642 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 8.75 2644.1 - 1.98E+06 - - - 1.0421 - 1.272 0.285 - 162.2 1 2 0 0.0009 8 0 0 0 1.04E+08 1.15E+08 - - - 1.8713 0.8953 230117_WJC_METTL3_WT_vs_EV_F06.11060.11060.2 0.00393 14-Jun Q.VLVLAPTR.E "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 867.5542 0.9 46362 11060 2 867.555237 434.7844 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.72 2645.4 - 2.36E+06 - - - 1.2091 - 1.335 0.283 - 111.6 1 1 0 0.001 8 0 0 0 1.29E+08 1.43E+08 - - - 2.0023 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.11063.11063.2 0.0784 12-Jun R.LIPTELR.R "sp|Q96G21|IMP4_HUMAN,tr|F8WCN0|F8WCN0_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN" 4 840.5069 1.08 46363 11063 2 840.50814 421.2607 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2645.8 - 1.66E+06 - - - 1.4717 - 1.227 0.254 - 153.5 1 2 0 0.0012 7 0 0 0 1.71E+08 1.58E+08 - - - 1.5649 0.9958 230117_WJC_METTL3_WT_vs_EV_F06.11068.11068.2 0.131 14-Jun R.ILMAINGK.V sp|O00264|PGRC1_HUMAN 1 858.4997 0.83 46364 11068 2 858.500874 430.2571 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 8.75 2646.5 - 2.81E+06 - - - 1.357 - 1.366 0.153 - 79.4 1 2 0 0.0012 8 0 0 0 9.33E+07 1.12E+08 - - - 1.1113 0.8558 230117_WJC_METTL3_WT_vs_EV_F06.11075.11075.2 2.38 16-May R.VDTDFMQLK[136.11].K "sp|Q9H6P5|TASP1_HUMAN,tr|Q5JWM4|Q5JWM4_HUMAN" 2 1103.5412 0.05 46367 11075 2 1103.539783 552.7779 Threonine aspartase 1 OS=Homo sapiens OX=9606 GN=TASP1 PE=1 SV=1 4.21 2647.5 - 472960 - - - -1.3257 - 0.922 0.103 - 73.4 2 2 0 -0.0015 9 0 0 0 9.90E+05 2.12E+07 - - - -0.5681 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.11076.11076.2 0.0979 14-Aug K.GIYALAAR.D "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 833.4759 0.77 46368 11076 2 833.477656 417.7452 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 8.75 2647.6 - 610963 - - - 2.0612 - 1.626 0.257 - 210.1 1 2 0 0.0017 8 0 0 0 6.91E+07 8.99E+07 - - - 2.4048 0.9924 230117_WJC_METTL3_WT_vs_EV_F06.11091.11091.2 0.326 12-Jun K.SVLIMGR[166.11].G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 784.4505 1.71 46371 11091 2 784.451592 393.2325 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.47 2649.9 - 170632 - - - 1.4367 - 1.334 0.096 - 116.1 1 2 0 0.0011 7 0 0 0 9.72E+07 5.67E+07 - - - 0.6628 0.997 230117_WJC_METTL3_WT_vs_EV_F06.11102.11102.2 1.38 12-Aug K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 0.97 46374 11102 2 828.474814 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2651.5 - 1.28E+06 - - - 1.8178 - 1.584 0.124 - 251.2 1 2 0 0.0015 7 0 0 0 3.31E+10 3.43E+10 - - - 1.4138 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.11108.11108.2 0.128 12-Jun K.DDAMLLK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 804.4051 1.45 46377 11108 2 804.407408 403.2098 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.21 2652.2 - 1.15E+06 - - - 2.8195 - 1.456 0.299 - 159.1 1 2 0 0.0023 7 0 0 0 4.61E+07 3.18E+07 - - - 2.4391 0.8789 230117_WJC_METTL3_WT_vs_EV_F06.11114.11114.2 8.81 12-May K.FIEIAAR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 818.465 0.97 46380 11114 2 818.464046 410.2398 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2653 - 4.37E+06 - - - -1.212 - 1.079 0.082 - 79.4 7 2 0 -0.001 7 0 0 0 3.31E+10 3.43E+10 - - - -0.4902 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.11123.11123.2 0.312 20-Sep K.IGGIGTVPVGR.V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1024.6029 6.19 46385 11123 2 1024.603567 513.3087 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2654.1 - 334857 - - - 0.6227 - 1.845 0.317 - 204.8 1 2 0 0.0006 11 0 0 0 1.09E+08 1.77E+07 - - - 3.0391 0.988 230117_WJC_METTL3_WT_vs_EV_F06.11134.11134.2 0.9 12-Jun K.SVLIMGR.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 774.4422 1.44 46388 11134 2 774.442496 388.2284 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.47 2655.7 - 1.97E+06 - - - 0.3887 - 1.281 0.089 - 160 1 2 0 0.0003 7 0 0 0 9.90E+07 6.86E+07 - - - 0.4829 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.11153.11153.2 1.13 14-Jul K.IGVTVLSR[166.11].L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 853.5261 0.92 46393 11153 2 853.525961 427.7703 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2658.5 - 1.05E+06 - - - -0.13 - 1.697 0.246 - 122.7 1 2 0 -0.0001 8 0 0 0 4.76E+08 5.19E+08 - - - 2.4529 0.9821 230117_WJC_METTL3_WT_vs_EV_F06.11161.11161.2 4.35 14-Jun R.ILMGSTLR[166.11].K "sp|P10644|KAP0_HUMAN,sp|P31321|KAP1_HUMAN,tr|K7EM13|K7EM13_HUMAN,tr|C9JSK5|C9JSK5_HUMAN,tr|K7EKR1|K7EKR1_HUMAN,tr|K7EPB2|K7EPB2_HUMAN,tr|H7BYW5|H7BYW5_HUMAN" 7 899.5138 1.58 46394 11161 2 899.516609 450.7642 cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1A PE=1 SV=1 9.75 2659.8 - 592081 - - - 3.1306 - 1.127 0.154 - 96.8 1 2 0 0.0028 8 0 0 0 3.80E+07 2.41E+07 - - - 0.5381 0.9486 230117_WJC_METTL3_WT_vs_EV_F06.11163.11163.2 1.77 12-May R.VYLGALK.Y sp|Q6P2Q9|PRP8_HUMAN 1 762.464 0.79 46395 11163 2 762.463635 382.2393 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.56 2660 - 1.63E+06 - - - -0.4472 - 1.026 0.133 - 71.3 5 2 0 -0.0003 7 0 0 0 2.82E+08 3.56E+08 - - - -0.2077 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.11168.11168.2 0.00211 14-Oct K.IGVTVLSR.L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 843.5178 0.92 46396 11168 2 843.516937 422.7662 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2660.7 - 2.00E+06 - - - -1.0255 - 1.854 0.287 - 294.5 1 2 0 -0.0009 8 0 0 0 4.76E+08 5.19E+08 - - - 3.0224 0.9802 230117_WJC_METTL3_WT_vs_EV_F06.11169.11169.2 0.836 12-Jul R.VYLGALK[136.11].Y sp|Q6P2Q9|PRP8_HUMAN 1 770.4782 1.09 46397 11169 2 770.477545 386.2464 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.56 2660.8 - 2.41E+06 - - - -0.819 - 1.273 0.108 - 173 1 2 0 -0.0006 7 0 0 0 2.46E+08 2.25E+08 - - - 0.6033 0.9562 230117_WJC_METTL3_WT_vs_EV_F06.11178.11178.2 4.13 14-Jul R.ILMGSTLR.K "sp|P10644|KAP0_HUMAN,sp|P31321|KAP1_HUMAN,tr|K7EM13|K7EM13_HUMAN,tr|C9JSK5|C9JSK5_HUMAN,tr|K7EKR1|K7EKR1_HUMAN,tr|K7EPB2|K7EPB2_HUMAN,tr|H7BYW5|H7BYW5_HUMAN" 7 889.5055 1.55 46400 11178 2 889.506504 445.76 cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1A PE=1 SV=1 9.75 2662 - 846722 - - - 1.1029 - 1.14 0.037 - 112.2 3 2 0 0.001 8 0 0 0 3.71E+07 2.40E+07 - - - -0.504 0.9867 230117_WJC_METTL3_WT_vs_EV_F06.11190.11190.2 8.91 12-Sep K.LGITQLR.F "sp|Q9Y285|SYFA_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 3 799.4916 2.58 46401 11190 2 799.490841 400.7531 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 9.75 2663.9 - 2.51E+06 - - - -0.9343 - 1.822 0.001 - 222.8 1 2 0 -0.0007 7 0 0 0 1.71E+08 6.64E+07 - - - 0.9491 0.9298 230117_WJC_METTL3_WT_vs_EV_F06.11191.11191.2 1.36 12-Jul K.LGITQLR[166.11].F "sp|Q9Y285|SYFA_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 3 809.4999 2.83 46402 11191 2 809.503649 405.7572 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 9.75 2664 - 938204 - - - 4.6831 - 1.479 0 - 121.4 1 2 0 0.0038 7 0 0 0 1.70E+08 6.01E+07 - - - 0.2799 0.962 230117_WJC_METTL3_WT_vs_EV_F06.11200.11200.2 1.12 12-Jun K.LPYSTFR[166.11].T "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 892.4682 1.23 46405 11200 2 892.467062 447.2414 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.75 2665.2 - 651783 - - - -1.3009 - 1.126 0.127 - 130.1 1 2 0 -0.0012 7 0 0 0 2.22E+08 1.81E+08 - - - 0.3547 0.9345 230117_WJC_METTL3_WT_vs_EV_F06.11205.11205.2 0.475 12-Jun K.LPYSTFR.T "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 882.46 1.23 46407 11205 2 882.457936 442.2373 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.75 2665.9 - 1.13E+06 - - - -2.2857 - 0.959 0.201 - 109 1 2 0 -0.002 7 0 0 0 2.22E+08 1.81E+08 - - - 0.3923 0.9952 230117_WJC_METTL3_WT_vs_EV_F06.11225.11225.2 0.0337 12-Jul R.VTVPLVR.R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 782.5014 0.94 46410 11225 2 782.500754 392.258 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2669 - 954404 - - - -0.8562 - 1.43 0.213 - 186 1 2 0 -0.0007 7 0 0 0 4.14E+08 4.41E+08 - - - 1.7473 0.9934 230117_WJC_METTL3_WT_vs_EV_F06.11230.11230.2 1.39 12-Jun R.VTVPLVR[166.11].R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 792.5097 0.94 46411 11230 2 792.509795 397.2621 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2669.7 - 2.24E+06 - - - 0.1274 - 1.313 0.15 - 152 1 2 0 0.0001 7 0 0 0 4.14E+08 4.40E+08 - - - 1.0117 0.9477 230117_WJC_METTL3_WT_vs_EV_F06.11275.11275.2 0.0968 14-Sep K.LTGVFAPR.P "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 859.4916 0.97 46420 11275 2 859.492308 430.7531 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2676.8 - 3.62E+07 - - - 0.8377 - 1.865 0.263 - 356.2 1 1 0 0.0007 8 0 0 0 2.40E+09 2.47E+09 - - - 2.863 0.9899 230117_WJC_METTL3_WT_vs_EV_F06.11295.11295.2 0.0872 14-Aug R.NLLLAGAK[136.11].V sp|Q9P2R3|ANFY1_HUMAN 1 806.5105 4.3 46426 11295 2 806.5117 404.2625 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 8.75 2679.7 - 250601 - - - 1.4395 - 1.42 0.05 - 168 1 2 0 0.0012 8 0 0 0 8.41E+07 1.96E+07 - - - 0.4675 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.11303.11303.2 3.30E-05 18-Jul K.NGQDLGVAFK[136.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1055.5491 1.51 46429 11303 2 1055.551131 528.7818 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2680.7 - 265048 - - - 1.9156 - 1.579 0.4 - 171.1 1 2 0 0.002 10 0 0 0 4.66E+07 3.10E+07 - - - 3.2698 0.998 230117_WJC_METTL3_WT_vs_EV_F06.11307.11307.2 0.051 12-Jun K.FMTDPIR.L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 878.432 0.93 46431 11307 2 878.433481 440.2233 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2681.3 - 833737 - - - 1.6586 - 1.246 0.273 - 177.9 1 2 0 0.0015 7 0 0 0 1.04E+08 1.11E+08 - - - 1.7538 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.11311.11311.2 2.5 12-Aug K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 0.97 46434 11311 2 828.474831 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2681.8 - 2.81E+06 - - - 1.8383 - 1.617 0.152 - 258.3 1 2 0 0.0015 7 0 0 0 3.32E+10 3.43E+10 - - - 1.6859 0.9009 230117_WJC_METTL3_WT_vs_EV_F06.11324.11324.2 5.32 12-Jun R.LIVNIAK[136.11].V sp|Q15058|KIF14_HUMAN 1 777.5204 1.62 46440 11324 2 777.522965 389.7675 Kinesin-like protein KIF14 OS=Homo sapiens OX=9606 GN=KIF14 PE=1 SV=1 8.75 2683.5 - 244541 - - - 3.3311 - 0.979 0.083 - 64 2 2 0 0.0026 7 0 0 0 1.25E+07 7.74E+06 - - - -0.5485 0.995 230117_WJC_METTL3_WT_vs_EV_F06.11327.11327.2 0.123 12-Jun K.FMTDPIR[166.11].L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 888.4403 1.21 46441 11327 2 888.442651 445.2274 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2683.9 - 2.34E+06 - - - 2.653 - 1.103 0.262 - 143.5 1 2 0 0.0024 7 0 0 0 1.35E+08 1.12E+08 - - - 1.286 0.9961 230117_WJC_METTL3_WT_vs_EV_F06.11339.11339.2 0.000107 14-Aug K.FGPALSVK[136.11].V "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 825.484 5.64 46445 11339 2 825.486606 413.7493 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.75 2685.8 - 2.27E+06 - - - 3.169 - 1.724 0.145 - 186.6 1 2 0 0.0026 8 0 0 0 3.47E+09 6.15E+08 - - - 1.7538 0.9787 230117_WJC_METTL3_WT_vs_EV_F06.11341.11341.2 9.94 12-Nov K.LAC[160.03]LLC[160.03]R[166.11].R "sp|P78332|RBM6_HUMAN,sp|P98175|RBM10_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 3 914.4705 0.43 46446 11341 2 914.471661 458.2426 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 8.07 2686 - 844491 - - - 1.216 - 1.315 0.007 - 636.1 1 2 0 0.0011 7 0 0 0 8.54E+06 1.97E+07 - - - -0.04 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.11349.11349.2 0.0749 12-Jul R.IVYLYTK[136.11].K sp|P49207|RL34_HUMAN 1 906.5306 0.76 46450 11349 2 906.53359 454.2726 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 8.5 2687 - 1.67E+06 - - - 3.2928 - 1.54 0.318 - 154.4 1 2 0 0.003 7 0 0 0 7.23E+08 9.56E+08 - - - 2.7569 0.9821 230117_WJC_METTL3_WT_vs_EV_F06.11351.11351.2 0.569 14-May K.VLEC[160.03]DIIK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 988.5263 0.28 46452 11351 2 988.528986 495.2704 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 2687.2 - 151711 - - - 2.699 - 1.156 0.12 - 71.2 1 2 0 0.0027 8 0 0 0 7.75E+06 2.73E+07 - - - 0.3637 1 230117_WJC_METTL3_WT_vs_EV_F06.11360.11360.2 9.25E-06 18-Oct K.NGQDLGVAFK.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1047.5349 1.35 46458 11360 2 1047.537681 524.7747 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2688.4 - 803839 - - - 2.6462 - 2.186 0.499 - 445.3 1 2 0 0.0028 10 0 0 0 4.17E+07 3.10E+07 - - - 4.9087 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.11363.11363.2 1.69 14-Jul K.LLLGDAPR.L "sp|Q96C00|ZBTB9_HUMAN,tr|A0A087X1K1|A0A087X1K1_HUMAN" 2 853.5022 0.74 46460 11363 2 853.503951 427.7584 Zinc finger and BTB domain-containing protein 9 OS=Homo sapiens OX=9606 GN=ZBTB9 PE=1 SV=1 5.84 2688.7 - 305156 - - - 2.1078 - 1.49 0.187 - 103.7 1 2 0 0.0018 8 0 0 0 2.51E+07 3.41E+07 - - - 1.6243 0.9443 230117_WJC_METTL3_WT_vs_EV_F06.11364.11364.2 0.00465 12-Jul K.MMEIMTR[166.11].E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 920.4157 0.87 46461 11364 2 920.419924 461.2151 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2688.8 - 238526 - - - 4.5512 - 1.198 0.105 - 167.5 1 2 0 0.0042 7 0 0 0 1.28E+08 1.47E+08 - - - 0.3876 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.11365.11365.2 0.000959 20-Aug K.ETTIDGEELVK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1240.6278 0.66 46462 11365 2 1240.630309 621.3212 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4 2689 - 106409 - - - 2.0119 - 1.565 0.417 - 178.6 1 2 0 0.0025 11 0 0 0 1.82E+06 2.77E+06 - - - 3.3318 0.9927 230117_WJC_METTL3_WT_vs_EV_F06.11368.11368.2 1.32 14-Aug R.VLAVTAIR[166.11].E sp|P22102|PUR2_HUMAN 1 851.5468 2.56 46463 11368 2 851.549083 426.7807 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2689.4 - 441739 - - - 2.6716 - 1.54 0.089 - 127.6 1 2 0 0.0023 8 0 0 0 3.50E+08 1.37E+08 - - - 0.9999 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.11373.11373.2 1.1 14-Jul R.VLAVTAIR.E sp|P22102|PUR2_HUMAN 1 841.5385 2.56 46466 11373 2 841.539902 421.7765 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2690.1 - 1.13E+06 - - - 1.6208 - 1.715 0.216 - 168.1 1 2 0 0.0014 8 0 0 0 3.50E+08 1.36E+08 - - - 2.2628 0.9874 230117_WJC_METTL3_WT_vs_EV_F06.11374.11374.2 1.29 14-Jul K.ALSVGLVK.G "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 3 785.5011 1.7 46467 11374 2 785.503378 393.7578 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 8.8 2690.2 - 295399 - - - 2.9128 - 1.236 0.138 - 125.6 1 2 0 0.0023 8 0 0 0 1.10E+08 6.50E+07 - - - 0.6986 0.885 230117_WJC_METTL3_WT_vs_EV_F06.11378.11378.2 4.7 14-May K.VLEC[160.03]DIIK[136.11].N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 996.5405 0.53 46471 11378 2 996.541652 499.2775 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 2690.7 - 115019 - - - 1.1379 - 1.018 0.004 - 49.2 4 2 0 0.0011 8 0 0 0 1.22E+07 2.29E+07 - - - -1.1449 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.11381.11381.2 0.0208 16-Aug R.MVGGVLVER[166.11].T sp|Q9UHV9|PFD2_HUMAN 1 968.5353 0.25 46472 11381 2 968.537311 485.2749 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 5.75 2691.1 - 1.36E+06 - - - 2.1207 - 1.495 0.245 - 192.3 1 2 0 0.0021 9 0 0 0 6.26E+07 2.46E+08 - - - 2.0133 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.11382.11382.2 0.00154 12-Jul K.MMVAGFK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 790.3961 0.89 46473 11382 2 790.397791 396.2053 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2691.3 - 1.05E+06 - - - 2.1369 - 1.555 0.412 - 248.4 1 2 0 0.0017 7 0 0 0 5.71E+09 6.42E+09 - - - 3.4823 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.11383.11383.2 0.00093 12-Aug K.MMEIMTR.E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 910.4075 0.87 46474 11383 2 910.410399 456.211 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2691.3 - 1.91E+06 - - - 3.2227 - 1.475 0.443 - 170.7 1 2 0 0.0029 7 0 0 0 1.28E+08 1.47E+08 - - - 3.5436 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.11389.11389.2 0.00025 12-Jun K.MMVAGFK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 782.3819 0.89 46476 11389 2 782.383208 392.1982 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2692.2 - 1.30E+06 - - - 1.6693 - 1.515 0.467 - 143.6 1 2 0 0.0013 7 0 0 0 5.71E+09 6.43E+09 - - - 3.8061 0.9889 230117_WJC_METTL3_WT_vs_EV_F06.11396.11396.2 0.968 12-Jul K.YLDEIVK.E sp|P12270|TPR_HUMAN 1 878.4749 1.91 46479 11396 2 878.475282 440.2447 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.37 2693.2 - 822533 - - - 0.395 - 1.125 0.152 - 128.9 1 2 0 0.0003 7 0 0 0 3.65E+07 1.91E+07 - - - 0.5368 0.9998 230117_WJC_METTL3_WT_vs_EV_F06.11403.11403.3 0.000101 Dec-52 K.SQIHDIVLVGGSTR.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1480.7998 43.25 46484 11403 3 1480.803183 494.6072 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2694 - 194040 - - - 2.2907 - 2.056 0.383 - 186.8 1 2 0 0.0034 14 0 0 0 1.42E+07 3.28E+05 - - - 4.7246 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.11404.11404.2 0.00168 18-Jul K.C[160.03]PFTGNVSIR[166.11].G "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1159.5683 1.04 46485 11404 2 1159.571507 580.7915 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.25 2694.2 - 130290 - - - 2.7243 - 1.343 0.395 - 159.4 1 2 0 0.0032 10 0 0 0 3.64E+06 3.49E+06 - - - 2.7807 0.9889 230117_WJC_METTL3_WT_vs_EV_F06.11410.11410.2 0.919 18-Nov K.YEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1178.5932 999 46489 11410 2 1178.587786 590.3039 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2694.9 - 196450 - - - -4.5529 - 2.149 0.304 - 552 1 2 0 -0.0054 10 0 0 0 2.27E+07 0.00E+00 - - - 3.42 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.11413.11413.2 0.162 14-Sep K.IVGYVLAK[136.11].M "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN" 4 869.5466 1.23 46490 11413 2 869.546924 435.7806 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 8.59 2695.4 - 1.43E+06 - - - 0.3841 - 1.377 0.295 - 187.9 1 2 0 0.0003 8 0 0 0 1.56E+08 1.26E+08 - - - 2.1846 0.9835 230117_WJC_METTL3_WT_vs_EV_F06.11430.11430.2 1.41 14-Jun R.GLGGIMVK.R sp|O94776|MTA2_HUMAN 1 773.4469 1.29 46499 11430 2 773.447202 387.7307 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 2697.4 - 971772 - - - 0.331 - 1.01 0.164 - 101.8 1 2 0 0.0003 8 0 0 0 4.82E+07 3.72E+07 - - - 0.2822 0.8553 230117_WJC_METTL3_WT_vs_EV_F06.11485.11485.2 8.17 14-Apr R.SFVIATTR.Q sp|Q9P253|VPS18_HUMAN 1 893.4971 999 46514 11485 2 893.501509 447.7558 Vacuolar protein sorting-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=VPS18 PE=1 SV=2 9.47 2705.3 - 384703 - - - 4.9715 - 0.988 0.166 - 58.1 6 2 0 0.0044 8 0 0 0 5.92E+06 0.00E+00 - - - -0.1183 0.9774 230117_WJC_METTL3_WT_vs_EV_F06.11498.11498.2 3.9 12-Aug K.LAPFIAK[136.11].R "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN,tr|K7ELX4|K7ELX4_HUMAN" 3 766.4833 1.64 46517 11498 2 766.48225 384.2489 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 8.75 2707.3 - 1.67E+06 - - - -1.319 - 1.334 0.106 - 166.7 1 2 0 -0.001 7 0 0 0 3.59E+08 2.19E+08 - - - 0.7367 0.9959 230117_WJC_METTL3_WT_vs_EV_F06.11508.11508.2 0.0105 16-Sep R.YLDGLTAER.T sp|P35908|K22E_HUMAN 1 1036.5189 0.59 46522 11508 2 1036.522783 519.2667 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2708.6 - 865958 - - - 3.7221 - 1.323 0.295 - 191.9 1 2 0 0.0039 9 0 0 0 2.03E+07 3.44E+07 - - - 2.0284 0.9904 230117_WJC_METTL3_WT_vs_EV_F06.11526.11526.2 1.2 14-Jul R.TIAPIIGR[166.11].T sp|Q99459|CDC5L_HUMAN 1 849.5312 2.69 46528 11526 2 849.532178 425.7729 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.41 2711.2 - 545762 - - - 1.2007 - 1.05 0.178 - 155.4 1 2 0 0.001 8 0 0 0 6.03E+07 2.24E+07 - - - 0.5025 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.11529.11529.2 0.0247 14-Jul K.GLYPAPLK[136.11].L "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 865.5153 1.62 46530 11529 2 865.516156 433.7649 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.59 2711.5 - 324875 - - - 1.0006 - 1.507 0.257 - 161.6 1 2 0 0.0009 8 0 0 0 5.25E+07 3.24E+07 - - - 2.1758 0.8962 230117_WJC_METTL3_WT_vs_EV_F06.11530.11530.2 2.99 14-Apr R.LLVPGTYK[136.11].L "sp|O75976|CBPD_HUMAN,tr|J3QQJ4|J3QQJ4_HUMAN" 2 897.5415 0.86 46531 11530 2 897.542668 449.778 Carboxypeptidase D OS=Homo sapiens OX=9606 GN=CPD PE=1 SV=2 8.59 2711.7 - 203952 - - - 1.2969 - 0.871 0.04 - 37.6 1 2 0 0.0012 8 0 0 0 1.33E+07 1.54E+07 - - - -1.0805 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.11533.11533.2 0.00802 16-Sep R.LLSPLSSAR[166.11].L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 952.5581 1.09 46532 11533 2 952.559384 477.2863 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 2712.1 - 1.32E+06 - - - 1.3469 - 1.778 0.334 - 267.6 1 2 0 0.0013 9 0 0 0 1.87E+08 1.72E+08 - - - 3.1724 0.9944 230117_WJC_METTL3_WT_vs_EV_F06.11535.11535.2 1.71 14-Sep R.TIAPIIGR.T sp|Q99459|CDC5L_HUMAN 1 839.5229 3.34 46533 11535 2 839.523709 420.7687 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.41 2712.3 - 433550 - - - 0.9779 - 1.39 0.119 - 196.7 1 2 0 0.0008 8 0 0 0 7.45E+07 2.23E+07 - - - 0.9128 0.987 230117_WJC_METTL3_WT_vs_EV_F06.11556.11556.2 3 12-Jul R.YLLYGEK[136.11].G "sp|P51398|RT29_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GYL9|V9GYL9_HUMAN" 3 892.4786 0.35 46542 11556 2 892.481308 447.2466 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 6 2715.2 - 778589 - - - 3.0679 - 1.356 0.1 - 170 1 2 0 0.0027 7 0 0 0 4.69E+07 1.35E+08 - - - 0.7437 0.9628 230117_WJC_METTL3_WT_vs_EV_F06.11563.11563.2 3.61 12-May R.AIAVFPR.K sp|O75096|LRP4_HUMAN 1 772.4596 0.72 46544 11563 2 772.460416 387.2371 Low-density lipoprotein receptor-related protein 4 OS=Homo sapiens OX=9606 GN=LRP4 PE=1 SV=4 9.79 2716.2 - 792072 - - - 1.1094 - 1.104 0.088 - 49.2 8 2 0 0.0009 7 0 0 0 3.75E+07 5.18E+07 - - - -0.3992 0.8806 230117_WJC_METTL3_WT_vs_EV_F06.11575.11575.2 0.0467 16-Aug N.LVIITAGAR[166.11].Q "sp|Q9BYZ2|LDH6B_HUMAN,sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 7 922.5839 0.94 46550 11575 2 922.586221 462.2992 L-lactate dehydrogenase A-like 6B OS=Homo sapiens OX=9606 GN=LDHAL6B PE=1 SV=3 9.75 2717.8 - 1.25E+06 - - - 2.4919 - 1.555 0.25 - 196.6 1 1 0 0.0023 9 0 0 0 1.46E+08 1.56E+08 - - - 2.164 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.11577.11577.2 0.0286 16-Sep R.LLSPLSSAR.L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 942.5498 1.09 46551 11577 2 942.551805 472.2822 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 2718 - 4.15E+06 - - - 2.0943 - 1.811 0.274 - 301.1 1 2 0 0.002 9 0 0 0 1.87E+08 1.72E+08 - - - 2.7823 0.9914 230117_WJC_METTL3_WT_vs_EV_F06.11578.11578.2 5.44 14-Sep R.IGLETSLR.Y sp|Q9Y230|RUVB2_HUMAN 1 887.5076 1.55 46552 11578 2 887.509667 444.7611 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6 2718.1 - 791534 - - - 2.2929 - 1.328 0.114 - 214.3 1 2 0 0.002 8 0 0 0 3.67E+07 2.37E+07 - - - 0.7379 0.9869 230117_WJC_METTL3_WT_vs_EV_F06.11582.11582.2 1.75 12-Jun R.VAGIFPR[166.11].L "sp|O96005|CLPT1_HUMAN,tr|K7EJ16|K7EJ16_HUMAN" 2 768.4522 0.8 46554 11582 2 768.452883 385.2334 Cleft lip and palate transmembrane protein 1 OS=Homo sapiens OX=9606 GN=CLPTM1 PE=1 SV=1 9.72 2718.5 - 873166 - - - 0.9161 - 1.175 0.103 - 118.3 1 2 0 0.0007 7 0 0 0 5.75E+07 7.23E+07 - - - 0.3125 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.11583.11583.2 0.0123 16-Oct R.LLPAELPAK[136.11].R sp|P78527|PRKDC_HUMAN 1 958.5943 1.25 46555 11583 2 958.596583 480.3044 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2718.7 - 330760 - - - 2.415 - 1.757 0.307 - 263.6 1 2 0 0.0023 9 0 0 0 4.92E+07 3.92E+07 - - - 2.9383 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.11595.11595.2 0.252 12-Aug R.IDGVLIR.M sp|O75663|TIPRL_HUMAN 1 784.4807 1.98 46558 11595 2 784.482243 393.2476 TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2 5.84 2720.5 - 1.15E+06 - - - 1.9809 - 1.768 0.184 - 149.2 1 2 0 0.0016 7 0 0 0 6.67E+07 3.36E+07 - - - 2.2051 0.9725 230117_WJC_METTL3_WT_vs_EV_F06.11603.11603.2 4.79 12-May R.FPGAYLK.G "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 794.4327 1.29 46562 11603 2 794.435382 398.2236 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.59 2721.4 - 1.01E+06 - - - 3.4062 - 1.148 0.148 - 51.9 3 2 0 0.0027 7 0 0 0 1.71E+08 1.32E+08 - - - 0.3575 0.9282 230117_WJC_METTL3_WT_vs_EV_F06.11608.11608.2 7.63 12-Jul R.FPGAYLK[136.11].G "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 802.4469 1.48 46563 11608 2 802.450403 402.2307 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.59 2722.1 - 585991 - - - 4.3953 - 1.095 0.109 - 154.3 1 2 0 0.0035 7 0 0 0 5.15E+07 3.47E+07 - - - 0.1325 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.11627.11627.2 0.021 14-Aug K.MVSAAFMK.K "sp|P25205|MCM3_HUMAN,tr|Q7Z6P5|Q7Z6P5_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 4 883.4296 2.75 46568 11627 2 883.430948 442.7221 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 8.5 2725 - 1.32E+06 - - - 1.5474 - 1.454 0.337 - 227.3 1 2 0 0.0014 8 0 0 0 5.46E+07 1.99E+07 - - - 2.6586 0.995 230117_WJC_METTL3_WT_vs_EV_F06.11629.11629.2 0.799 14-Jul R.FGPLASVK.L "sp|O15042|SR140_HUMAN,tr|E7EW00|E7EW00_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H0Y8D9|H0Y8D9_HUMAN" 4 817.4698 0.17 46569 11629 2 817.469621 409.7422 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 8.75 2725.2 - 699554 - - - -0.2067 - 1.408 0.176 - 118.5 1 2 0 -0.0002 8 0 0 0 1.20E+08 7.25E+08 - - - 1.3729 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.11634.11634.2 0.161 12-Aug K.LLQEIVR.S "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 869.5335 1.45 46573 11634 2 869.534564 435.774 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6 2725.8 - 1.16E+06 - - - 1.2788 - 1.583 0.291 - 198.6 1 2 0 0.0011 7 0 0 0 6.95E+07 4.81E+07 - - - 2.6454 1 230117_WJC_METTL3_WT_vs_EV_F06.11635.11635.2 1.49E-05 12-Aug K.C[160.03]PVFVVR.W "sp|Q9C0J8|WDR33_HUMAN,tr|C9J8B4|C9J8B4_HUMAN" 2 875.4687 1.66 46574 11635 2 875.46965 438.7416 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 8.25 2725.9 - 1.08E+06 - - - 1.0349 - 1.872 0.557 - 374.2 1 2 0 0.0009 7 0 0 0 9.50E+07 5.73E+07 - - - 5.1414 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.11640.11640.2 0.0793 14-Sep R.MVLVGDVK.D "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PEU0|A0A6Q8PEU0_HUMAN,tr|A0A6Q8PHI4|A0A6Q8PHI4_HUMAN,tr|A0A6Q8PG82|A0A6Q8PG82_HUMAN" 7 859.4837 1.99 46577 11640 2 859.484621 430.7491 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 5.59 2726.4 - 1.63E+06 - - - 1.0425 - 1.372 0.283 - 278.1 1 2 0 0.0009 8 0 0 0 2.05E+08 1.03E+08 - - - 2.0848 0.9946 230117_WJC_METTL3_WT_vs_EV_F06.11641.11641.2 0.127 20-Jun K.VLFSSNGGVVK.G "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 1105.6132 1.23 46578 11641 2 1105.615037 553.8139 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.72 2726.5 - 188646 - - - 1.6986 - 1.233 0.223 - 82.2 5 2 0 0.0019 11 0 0 0 1.10E+07 8.93E+06 - - - 0.9419 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.11648.11648.2 0.239 14-Aug K.LINAVELK[136.11].K sp|P56192|SYMC_HUMAN 1 906.563 1.08 46580 11648 2 906.564473 454.2888 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6 2727.5 - 4.28E+06 - - - 1.6601 - 1.641 0.207 - 153.5 1 2 0 0.0015 8 0 0 0 1.88E+08 1.74E+08 - - - 2.0632 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.11654.11654.2 0.178 14-Sep R.LLGQIVDR[166.11].C sp|Q96I24|FUBP3_HUMAN 1 922.5475 1.48 46583 11654 2 922.548603 462.281 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2728.3 - 1.46E+06 - - - 1.1566 - 1.484 0.194 - 225.7 1 2 0 0.0011 8 0 0 0 1.05E+09 7.11E+08 - - - 1.6641 1 230117_WJC_METTL3_WT_vs_EV_F06.11671.11671.3 8.02E-13 20/84 K.DHTPSQELALTQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2270.0411 999 46589 11671 3 2270.041754 757.6876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2730.6 - 187104 - - - 0.2894 - 4.024 0.726 - 419.6 1 2 0 0.0007 22 0 0 0 4.68E+06 0.00E+00 - - - 9.9349 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.11681.11681.2 0.105 14-Aug R.LVSLIGSK.T "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 815.5117 2.02 46595 11681 2 815.51359 408.7631 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 2731.9 - 853005 - - - 2.374 - 1.517 0.252 - 171.4 1 2 0 0.0019 8 0 0 0 7.15E+07 3.53E+07 - - - 2.1585 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.11682.11682.2 0.000771 16-Aug K.NDLAVVDVR[166.11].L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1009.5432 0.74 46596 11682 2 1009.545237 505.7789 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.21 2732 - 455968 - - - 2.0385 - 1.671 0.401 - 298 1 2 0 0.0021 9 0 0 0 1.32E+07 1.80E+07 - - - 3.4875 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.11689.11689.2 0.0169 14-Sep R.LLGQIVDR.C sp|Q96I24|FUBP3_HUMAN 1 912.5393 1.48 46600 11689 2 912.541452 457.2769 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2732.8 - 1.80E+07 - - - 2.3955 - 1.625 0.254 - 204.9 1 2 0 0.0022 8 0 0 0 1.05E+09 7.11E+08 - - - 2.3806 0.9847 230117_WJC_METTL3_WT_vs_EV_F06.11692.11692.2 0.628 16-Apr K.SC[160.03]AHDWVYE.- "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 3 1165.4499 - 46601 11692 2 1165.452743 583.7322 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 4.71 2733.2 - 61146.1 - - - 2.4746 - 0.768 0.286 - 47.2 1 2 0 0.0029 9 0 0 0 - - - - - 0.3888 0.999 230117_WJC_METTL3_WT_vs_EV_F06.11706.11706.2 0.00262 20-Oct K.LLAETVAPAVR[166.11].G "sp|Q9BSJ8|ESYT1_HUMAN,tr|F8VZB1|F8VZB1_HUMAN" 2 1148.6793 0.7 46607 11706 2 1148.678411 575.3469 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6 2735 - 232043 - - - -0.7557 - 2.022 0.343 - 285.4 1 2 0 -0.0009 11 0 0 0 1.25E+07 1.78E+07 - - - 3.4788 0.9961 230117_WJC_METTL3_WT_vs_EV_F06.11708.11708.2 0.0824 12-Jun K.YVMVVYK.R "sp|Q9BPX3|CND3_HUMAN,tr|D6RA93|D6RA93_HUMAN" 2 900.4779 3 46609 11708 2 900.480677 451.2462 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 8.5 2735.2 - 553826 - - - 3.0717 - 1.137 0.306 - 123.3 1 2 0 0.0028 7 0 0 0 1.62E+07 5.41E+06 - - - 1.7071 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.11713.11713.2 0.00781 20-Oct K.LLAETVAPAVR.G "sp|Q9BSJ8|ESYT1_HUMAN,tr|F8VZB1|F8VZB1_HUMAN" 2 1138.671 0.73 46611 11713 2 1138.676224 570.3428 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6 2735.9 - 255746 - - - 4.5799 - 1.779 0.427 - 338.5 1 2 0 0.0052 11 0 0 0 1.25E+07 1.72E+07 - - - 3.7515 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.11714.11714.3 1.56E-05 Sep-68 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 4.53 46612 11714 3 2070.869181 691.296 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2736 - 124947 - - - 1.3951 - 1.689 0.574 - 63.9 1 2 0 0.0029 18 0 0 0 3.67E+06 8.10E+05 - - - 6.2439 0.994 230117_WJC_METTL3_WT_vs_EV_F06.11717.11717.2 0.355 20-Jun R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 0.83 46613 11717 2 1166.703023 584.3584 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2736.4 - 139461 - - - 0.612 - 1.285 0.163 - 80.2 1 2 0 0.0007 11 0 0 0 5.86E+07 7.07E+07 - - - 0.9231 0.9885 230117_WJC_METTL3_WT_vs_EV_F06.11719.11719.2 0.908 14-Jun R.LVSLIGSK[136.11].T "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 823.5259 2.04 46614 11719 2 823.526951 412.7702 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 2736.6 - 845915 - - - 1.3321 - 1.233 0.131 - 67.3 4 2 0 0.0011 8 0 0 0 7.23E+07 3.55E+07 - - - 0.371 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.11720.11720.2 0.0351 24-Aug R.SILSPGGSC[160.03]GPIK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1279.6686 0.92 46615 11720 2 1279.671242 640.8416 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 7.94 2736.8 - 106233 - - - 2.0857 - 1.408 0.321 - 106.5 1 2 0 0.0027 13 0 0 0 4.76E+06 5.20E+06 - - - 2.2893 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.11731.11731.2 0.117 14-Jul K.LGDIMGVK[136.11].K sp|Q92620|PRP16_HUMAN 1 839.4666 0.24 46621 11731 2 839.467632 420.7406 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38 PE=1 SV=2 5.84 2738.2 - 400918 - - - 1.1996 - 1.507 0.22 - 76.2 1 2 0 0.001 8 0 0 0 1.15E+07 4.78E+07 - - - 1.9025 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.11738.11738.2 0.0179 20-Dec R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 0.83 46625 11738 2 1174.719364 588.3655 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2739 - 779344 - - - 2.4304 - 2.134 0.386 - 465.3 1 2 0 0.0029 11 0 0 0 5.87E+07 7.07E+07 - - - 3.9417 0.9056 230117_WJC_METTL3_WT_vs_EV_F06.11739.11739.2 0.0436 18-Oct L.LASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1053.6182 0.74 46626 11739 2 1053.622248 527.8164 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2739.1 - 223576 - - - 3.7993 - 1.943 0.347 - 218 1 1 0 0.004 10 0 0 0 9.88E+06 1.34E+07 - - - 3.4568 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.11740.11740.3 0.0265 16/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 0.77 46627 11740 3 1166.705102 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2739.2 - 2.93E+06 - - - 2.3939 - 2.922 0.246 - 252 1 2 0 0.0028 11 0 0 0 2.55E+08 3.29E+08 - - - 4.328 0.9943 230117_WJC_METTL3_WT_vs_EV_F06.11742.11742.2 0.738 12-Aug K.LGLQSLR[166.11].N "sp|P18085|ARF4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 3 795.4842 2.43 46628 11742 2 795.485063 398.7494 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 9.75 2739.4 - 1.16E+06 - - - 1.0748 - 1.332 0.126 - 173 1 2 0 0.0009 7 0 0 0 2.04E+08 8.39E+07 - - - 0.8797 1 230117_WJC_METTL3_WT_vs_EV_F06.11746.11746.2 2.30E-08 Sep-32 N.IVSNASC[160.03]TTNC[160.03]LAPLAK.V "sp|O14556|G3PT_HUMAN,tr|K7EP73|K7EP73_HUMAN" 2 1818.8968 999 46631 11746 2 1818.901226 910.4557 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 8.06 2739.8 - 121983 - - - 2.4306 - 2.379 0.57 - 155.7 1 1 0 0.0044 17 0 0 0 6.70E+06 0.00E+00 - - - 5.3804 0.997 230117_WJC_METTL3_WT_vs_EV_F06.11749.11749.3 0.0144 Dec-40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 0.77 46632 11749 3 1174.718245 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2740.2 - 7.19E+06 - - - 1.4778 - 2.335 0.126 - 110.9 1 2 0 0.0017 11 0 0 0 2.55E+08 3.29E+08 - - - 2.3534 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.11753.11753.2 0.000179 12-Jul R.VFVVMEK.L "sp|Q15139|KPCD1_HUMAN,sp|O94806|KPCD3_HUMAN,sp|Q9BZL6|KPCD2_HUMAN,tr|M0R2Z8|M0R2Z8_HUMAN,tr|F8WBA3|F8WBA3_HUMAN" 5 850.4623 0.26 46633 11753 2 850.462872 426.2384 Serine\threonine-protein kinase D1 OS=Homo sapiens OX=9606 GN=PRKD1 PE=1 SV=2 5.97 2740.9 - 187944 - - - 0.7184 - 1.666 0.283 - 156.7 1 2 0 0.0006 7 0 0 0 1.49E+07 5.73E+07 - - - 2.7484 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.11756.11756.2 0.136 12-Jul R.VVVEYLR.A sp|O60645|EXOC3_HUMAN 1 876.5069 1.38 46634 11756 2 876.508365 439.2607 Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3 5.97 2741.3 - 439063 - - - 1.668 - 1.488 0.252 - 202.1 1 2 0 0.0015 7 0 0 0 4.81E+07 3.49E+07 - - - 2.1611 0.9789 230117_WJC_METTL3_WT_vs_EV_F06.11761.11761.2 0.00211 16-Oct L.ASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 940.5342 0.93 46636 11761 2 940.535541 471.2744 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 2741.9 - 624585 - - - 1.446 - 2.282 0.398 - 444.5 1 1 0 0.0014 9 0 0 0 2.14E+07 2.29E+07 - - - 4.3671 0.9965 230117_WJC_METTL3_WT_vs_EV_F06.11796.11796.2 0.853 14-Jul R.ILDAPEIR.N sp|Q12834|CDC20_HUMAN 1 925.5233 2.05 46654 11796 2 925.525608 463.7689 Cell division cycle protein 20 homolog OS=Homo sapiens OX=9606 GN=CDC20 PE=1 SV=2 4.37 2746.4 - 515790 - - - 2.5132 - 1.454 0.184 - 113.5 1 2 0 0.0023 8 0 0 0 1.79E+07 8.75E+06 - - - 1.5282 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.11805.11805.2 0.0413 16-Oct K.VGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 911.5804 1.99 46658 11805 2 911.581248 456.7975 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2747.6 - 586227 - - - 0.927 - 2.02 0.222 - 199.7 1 2 0 0.0008 9 0 0 0 7.04E+08 3.54E+08 - - - 2.7145 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.11809.11809.2 0.00014 18-Aug K.YEELQVTVGR.H sp|P35908|K22E_HUMAN 1 1192.6088 999 46660 11809 2 1192.61258 597.3117 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.53 2748 - 86148.5 - - - 3.1678 - 1.811 0.441 - 249.2 1 2 0 0.0038 10 0 0 0 2.55E+06 0.00E+00 - - - 3.9547 0.9964 230117_WJC_METTL3_WT_vs_EV_F06.11811.11811.2 0.00915 12-Jun K.LDPVLYR[166.11].K "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 884.4995 0.92 46662 11811 2 884.500597 443.257 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 5.84 2748.2 - 3.14E+06 - - - 1.2142 - 1.301 0.185 - 165.8 1 2 0 0.0011 7 0 0 0 1.20E+08 1.31E+08 - - - 1.2408 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.11812.11812.2 0.544 16-Oct K.VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 919.5946 1.99 46663 11812 2 919.595232 460.8046 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2748.4 - 575372 - - - 0.684 - 1.98 0.26 - 234.3 1 2 0 0.0006 9 0 0 0 7.04E+08 3.54E+08 - - - 2.9374 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.11822.11822.2 0.439 12-Aug K.LEDLIVK[136.11].D "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 836.5099 2 46666 11822 2 836.510608 419.2622 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2749.7 - 4.41E+06 - - - 0.8822 - 1.905 0.063 - 193.3 1 2 0 0.0007 7 0 0 0 1.36E+09 6.81E+08 - - - 1.5482 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.11824.11824.2 1.18 12-Aug R.LGLTEIR[166.11].K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 810.4839 1.2 46667 11824 2 810.484649 406.2492 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2750 - 1.76E+06 - - - 0.9575 - 1.684 0.146 - 197 1 2 0 0.0008 7 0 0 0 1.05E+09 8.80E+08 - - - 1.7705 0.9223 230117_WJC_METTL3_WT_vs_EV_F06.11828.11828.2 5.23 12-Jun R.LLLPGTR.A sp|Q6P087|RUSD3_HUMAN 1 768.4858 1.45 46668 11828 2 768.487124 385.2502 Mitochondrial mRNA pseudouridine synthase RPUSD3 OS=Homo sapiens OX=9606 GN=RPUSD3 PE=1 SV=3 9.75 2750.6 - 615644 - - - 1.7567 - 1.172 0 - 131 8 2 0 0.0014 7 0 0 0 4.63E+07 3.19E+07 - - - -0.8599 0.8621 230117_WJC_METTL3_WT_vs_EV_F06.11830.11830.2 2.55 12-Apr K.FLEATLR[166.11].S "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN" 2 858.4839 0.73 46669 11830 2 858.484647 430.2492 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 6 2750.8 - 469690 - - - 0.9016 - 1.062 0.012 - 33.9 19 2 0 0.0008 7 0 0 0 3.63E+07 4.97E+07 - - - -1.2512 0.9952 230117_WJC_METTL3_WT_vs_EV_F06.11832.11832.2 2.61 12-Jul R.LGLTEIR.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 800.4756 1.2 46670 11832 2 800.476807 401.2451 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2751 - 2.65E+06 - - - 1.5041 - 1.558 0.077 - 142.5 1 2 0 0.0012 7 0 0 0 1.06E+09 8.81E+08 - - - 1.0143 0.9836 230117_WJC_METTL3_WT_vs_EV_F06.11833.11833.2 3.11 12-Jun K.FLEATLR.S "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN" 2 848.4756 0.75 46671 11833 2 848.475524 425.2451 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 6 2751.2 - 249429 - - - -0.0931 - 1.41 0.041 - 109.7 1 2 0 -0.0001 7 0 0 0 3.59E+07 4.79E+07 - - - 0.4325 0.999 230117_WJC_METTL3_WT_vs_EV_F06.11837.11837.2 0.0886 18-Jul K.LITPAVVSER[166.11].L sp|P62851|RS25_HUMAN 1 1093.6371 1.14 46673 11837 2 1093.638836 547.8258 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 6 2751.7 - 144979 - - - 1.6066 - 1.542 0.29 - 133.2 1 2 0 0.0018 10 0 0 0 1.20E+07 1.05E+07 - - - 2.3912 0.9729 230117_WJC_METTL3_WT_vs_EV_F06.11845.11845.2 0.851 12-May R.LAVYC[160.03]LK.D "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 865.4732 0.84 46676 11845 2 865.476557 433.7439 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.2 2752.7 - 292693 - - - 3.9239 - 1.156 0.15 - 67.2 1 2 0 0.0034 7 0 0 0 4.14E+07 4.93E+07 - - - 0.6072 0.9768 230117_WJC_METTL3_WT_vs_EV_F06.11858.11858.2 0.35 12-May K.LMPTQWR.T sp|Q99459|CDC5L_HUMAN 1 930.4746 1.14 46681 11858 2 930.475199 466.2446 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.75 2754.5 - 423053 - - - 0.69 - 1.031 0.141 - 86.2 3 2 0 0.0006 7 0 0 0 4.76E+07 4.19E+07 - - - -0.0342 0.9454 230117_WJC_METTL3_WT_vs_EV_F06.11864.11864.2 0.944 12-Jun K.AFMGPLK[136.11].K "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN" 2 770.424 1.02 46683 11864 2 770.422739 386.2193 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 8.8 2755.3 - 890187 - - - -1.6783 - 1.135 0.111 - 84.9 1 2 0 -0.0013 7 0 0 0 5.82E+07 5.68E+07 - - - 0.2617 0.9912 230117_WJC_METTL3_WT_vs_EV_F06.11872.11872.2 0.49 14-Jul K.LIEQYALR[166.11].E sp|Q9NUQ3|TXLNG_HUMAN 1 1014.5738 1.47 46686 11872 2 1014.574775 508.2942 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2756.5 - 271715 - - - 1.0093 - 1.287 0.105 - 144.4 1 2 0 0.001 8 0 0 0 4.06E+07 2.76E+07 - - - 0.5772 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.11880.11880.2 0.184 14-Jul K.LIEQYALR.E sp|Q9NUQ3|TXLNG_HUMAN 1 1004.5655 1.47 46687 11880 2 1004.565309 503.29 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2757.8 - 633694 - - - -0.1712 - 1.527 0.209 - 141.9 1 2 0 -0.0002 8 0 0 0 4.06E+07 2.76E+07 - - - 1.8613 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.11883.11883.2 1.37 12-Jun K.AFMGPLK.K "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN" 2 762.4098 0.99 46688 11883 2 762.409557 382.2122 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 8.8 2758.1 - 1.09E+06 - - - -0.3607 - 1.276 0.239 - 153.3 1 2 0 -0.0003 7 0 0 0 6.11E+07 6.15E+07 - - - 1.5784 0.991 230117_WJC_METTL3_WT_vs_EV_F06.11933.11933.2 0.433 12-Jul K.FVNLYTR[166.11].E "sp|Q15650|TRIP4_HUMAN,tr|H0YL91|H0YL91_HUMAN" 2 921.4948 2.01 46709 11933 2 921.495163 461.7547 Activating signal cointegrator 1 OS=Homo sapiens OX=9606 GN=TRIP4 PE=1 SV=4 8.75 2764.8 - 238096 - - - 0.4243 - 1.134 0.168 - 137.4 1 2 0 0.0004 7 0 0 0 2.12E+07 1.05E+07 - - - 0.6802 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.11937.11937.2 0.0102 14-Aug K.VPYLAVAR[166.11].T "sp|P18858|DNLI1_HUMAN,tr|F5GZ28|F5GZ28_HUMAN,tr|M0R0Q7|M0R0Q7_HUMAN,tr|B4E135|B4E135_HUMAN" 4 897.5312 1.94 46711 11937 2 897.53298 449.7729 DNA ligase 1 OS=Homo sapiens OX=9606 GN=LIG1 PE=1 SV=1 8.72 2765.4 - 284913 - - - 2.03 - 1.466 0.255 - 162.6 1 2 0 0.0018 8 0 0 0 2.42E+07 1.25E+07 - - - 2.0776 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.11942.11942.2 0.029 24-Aug R.GGIGAGLGGGLC[160.03]R.R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1143.5819 0.53 46714 11942 2 1143.58303 572.7982 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2765.9 - 152203 - - - 1.0091 - 1.592 0.254 - 130.1 1 2 0 0.0012 13 0 0 0 7.76E+06 1.46E+07 - - - 2.1101 0.9236 230117_WJC_METTL3_WT_vs_EV_F06.11954.11954.4 0.163 Nov-96 T.LLLIILTDVFIISTVLR.L sp|Q8NGY0|O10X1_HUMAN 1 1941.2278 999 46721 11954 4 1941.234411 486.3142 Olfactory receptor 10X1 OS=Homo sapiens OX=9606 GN=OR10X1 PE=3 SV=2 5.84 2767.5 - 381002 - - - 3.3942 - 1.36 0.283 - 64.5 1 1 0 0.0066 17 0 0 0 1.35E+07 0.00E+00 - - - 1.7942 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.11959.11959.2 0.174 13/24 R.GGIGAGLGGGLC[160.03]R[166.11].R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1153.5901 0.54 46724 11959 2 1153.593292 577.8023 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2768.1 - 430634 - - - 2.7271 - 2.12 0.319 - 420.7 1 2 0 0.0031 13 0 0 0 7.86E+06 1.46E+07 - - - 3.3247 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.11970.11970.2 0.0993 16-Aug R.LITGLGVGR[166.11].E sp|Q9BQG0|MBB1A_HUMAN 1 894.5526 1.05 46731 11970 2 894.555298 448.2836 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 9.75 2769.5 - 793132 - - - 2.9926 - 1.665 0.258 - 152.3 1 2 0 0.0027 9 0 0 0 1.31E+08 1.25E+08 - - - 2.4207 0.9928 230117_WJC_METTL3_WT_vs_EV_F06.11982.11982.2 0.701 12-Jun R.FALVTPK[136.11].K sp|P49792|RBP2_HUMAN 1 782.4782 0.87 46739 11982 2 782.479607 392.2464 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.75 2770.9 - 640793 - - - 1.8288 - 1.256 0.133 - 83.6 1 2 0 0.0014 7 0 0 0 4.97E+07 5.71E+07 - - - 0.7451 0.9945 230117_WJC_METTL3_WT_vs_EV_F06.11987.11987.2 0.227 12-Jun R.AAYIYIR[166.11].G "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|B4DE93|B4DE93_HUMAN,tr|E9PJL9|E9PJL9_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PLC6|E9PLC6_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN" 8 878.489 5.35 46742 11987 2 878.489191 440.2518 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.63 2771.5 - 537903 - - - 0.2641 - 1.228 0.191 - 142.7 1 2 0 0.0002 7 0 0 0 1.10E+08 2.06E+07 - - - 1.1024 0.999 230117_WJC_METTL3_WT_vs_EV_F06.12015.12015.2 0.0188 16-Oct R.LITGLGVGR.E sp|Q9BQG0|MBB1A_HUMAN 1 884.5444 1.1 46753 12015 2 884.543556 443.2795 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 9.75 2775.1 - 2.92E+06 - - - -0.8988 - 1.812 0.373 - 241.5 1 2 0 -0.0008 9 0 0 0 1.37E+08 1.25E+08 - - - 3.5154 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.12016.12016.2 0.156 14-Aug R.ALLGPALK.D sp|P35250|RFC2_HUMAN 1 781.5062 1.88 46754 12016 2 781.5052 391.7604 Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3 8.8 2775.1 - 2.24E+06 - - - -1.2476 - 1.581 0.279 - 190.3 1 2 0 -0.001 8 0 0 0 1.13E+08 6.02E+07 - - - 2.4829 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.12025.12025.2 0.0152 12-Aug K.VPVNLLR[166.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 819.5206 1.17 46755 12025 2 819.520239 410.7676 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2776.6 - 704381 - - - -0.432 - 1.516 0.327 - 332 1 2 0 -0.0004 7 0 0 0 1.44E+08 1.23E+08 - - - 2.7745 1 230117_WJC_METTL3_WT_vs_EV_F06.12031.12031.2 0.000606 14/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 46757 12031 2 1302.608941 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2777.4 - 6.66E+06 - - - -0.1958 - 2.35 0.533 - 398.2 1 2 0 -0.0003 13 0 0 0 1.86E+09 0.00E+00 - - - 5.1705 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.12032.12032.2 0.0873 14-Sep K.ILVDALQK[136.11].F "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 15 906.563 1.13 46758 12032 2 906.562327 454.2888 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 5.84 2777.5 - 877800 - - - -0.7071 - 1.897 0.298 - 196.6 1 2 0 -0.0006 8 0 0 0 6.73E+07 5.96E+07 - - - 3.1729 0.9476 230117_WJC_METTL3_WT_vs_EV_F06.12036.12036.2 2.7 12-Jun K.IDPLLPK.E sp|Q9BYD6|RM01_HUMAN 1 794.4902 2.43 46759 12036 2 794.489426 398.2524 "39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2" 5.84 2778.1 - 1.31E+06 - - - -0.9629 - 1.164 0.063 - 97 1 2 0 -0.0008 7 0 0 0 2.38E+08 9.80E+07 - - - -0.0127 0.999 230117_WJC_METTL3_WT_vs_EV_F06.12042.12042.2 2.72E-05 20-Nov R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 6332.89 46762 12042 2 1201.608018 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2778.8 - 1.53E+06 - - - -0.9313 - 1.938 0.377 - 191.5 1 2 0 -0.0011 11 0 0 0 6.40E+09 1.01E+06 - - - 3.6151 0.985 230117_WJC_METTL3_WT_vs_EV_F06.12045.12045.2 0.117 18-Aug K.QLVTNAC[160.03]LIK[136.11].E "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 3 1166.6573 0.23 46764 12045 2 1166.657232 584.3359 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 8.22 2779.2 - 219693 - - - -0.0411 - 1.275 0.102 - 154.8 1 2 0 0 10 0 0 0 1.07E+06 4.74E+06 - - - 0.4725 0.9931 230117_WJC_METTL3_WT_vs_EV_F06.12048.12048.2 1.02 14-Aug R.ALLGPALK[136.11].D sp|P35250|RFC2_HUMAN 1 789.5204 1.87 46765 12048 2 789.519679 395.7675 Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3 8.8 2779.6 - 1.06E+06 - - - -0.8815 - 1.392 0.19 - 184.7 1 2 0 -0.0007 8 0 0 0 1.12E+08 5.98E+07 - - - 1.4416 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.12060.12060.2 0.000658 12-Aug R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.63 46769 12060 2 852.483607 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2781.3 - 1.97E+07 - - - -0.0563 - 1.578 0.3 - 205.2 1 2 0 0 7 0 0 0 2.29E+09 1.40E+09 - - - 2.7021 0.8626 230117_WJC_METTL3_WT_vs_EV_F06.12067.12067.2 0.0203 18-Jul R.LVHPGVAEVV.F "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1018.5811 - 46773 12067 2 1018.580563 510.2978 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.24 2782.1 - 319464 - - - -0.5576 - 1.441 0.318 - 102.9 1 1 0 -0.0006 10 0 0 0 - - - - - 2.4093 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.12081.12081.2 0.347 14-Jun K.ILFTEATR.L "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 949.5233 1.9 46780 12081 2 949.524499 475.7689 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 6 2783.9 - 1.36E+06 - - - 1.2817 - 1.353 0.307 - 106.4 1 2 0 0.0012 8 0 0 0 4.54E+07 2.39E+07 - - - 2.2199 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.12084.12084.3 0.000444 13/40 R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 3031.41 46781 12084 3 1201.608753 401.5437 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2784.3 - 3.32E+06 - - - -0.3196 - 1.997 0.232 - 264.7 1 2 0 -0.0004 11 0 0 0 3.57E+08 1.18E+05 - - - 3.0913 0.9677 230117_WJC_METTL3_WT_vs_EV_F06.12096.12096.2 0.097 12-Jun K.GLVLMSR[166.11].A "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 16 784.4505 1.24 46785 12096 2 784.450312 393.2325 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 9.75 2786 - 4.16E+06 - - - -0.195 - 1.356 0 - 137.1 1 2 0 -0.0002 7 0 0 0 4.80E+08 3.86E+08 - - - 0.0059 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.12106.12106.2 0.042 14-Aug R.TFGVSPLR.R sp|Q5T750|XP32_HUMAN 1 875.4865 24.1 46789 12106 2 875.487879 438.7505 Skin-specific protein 32 OS=Homo sapiens OX=9606 GN=XP32 PE=1 SV=1 9.41 2787.2 - 1.73E+06 - - - 1.5728 - 1.417 0.374 - 199.2 1 2 0 0.0014 8 0 0 0 7.87E+07 3.27E+06 - - - 2.8541 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.12110.12110.2 0.0685 16-Aug K.IPTPIVGVK.R "sp|P51003|PAPOA_HUMAN,tr|G3XAH6|G3XAH6_HUMAN,tr|H0YJL4|H0YJL4_HUMAN" 3 922.5852 2.55 46793 12110 2 922.586343 462.2999 Poly(A) polymerase alpha OS=Homo sapiens OX=9606 GN=PAPOLA PE=1 SV=4 8.75 2787.8 - 347797 - - - 1.2888 - 1.36 0.22 - 139.4 1 2 0 0.0012 9 0 0 0 7.03E+06 2.75E+06 - - - 1.5551 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.12114.12114.2 0.00053 14-Sep K.VVNPYYLR.V sp|Q13131|AAPK1_HUMAN 1 1022.5549 1.69 46795 12114 2 1022.555908 512.2847 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4 8.56 2788.3 - 262584 - - - 0.9701 - 1.938 0.403 - 321.9 1 2 0 0.001 8 0 0 0 8.75E+06 5.19E+06 - - - 4.0128 0.9851 230117_WJC_METTL3_WT_vs_EV_F06.12116.12116.2 0.488 12-Jun R.ILLYAC[160.03]R.N "sp|P36954|RPB9_HUMAN,tr|K7EKS1|K7EKS1_HUMAN" 2 907.495 1.08 46797 12116 2 907.49357 454.7548 DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1 8.22 2788.4 - 596491 - - - -1.5306 - 1.305 0.172 - 115 1 2 0 -0.0014 7 0 0 0 7.15E+07 6.65E+07 - - - 1.1544 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.12117.12117.2 0.0212 16-Sep R.NVIEAVYSR[166.11].L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1059.5588 1.4 46798 12117 2 1059.557792 530.7867 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 2788.6 - 573996 - - - -0.9787 - 1.544 0.321 - 247.2 1 2 0 -0.001 9 0 0 0 5.99E+07 4.28E+07 - - - 2.6683 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.12122.12122.2 0.0177 16-Aug M.PLPVALQTR[166.11].L "sp|O60828|PQBP1_HUMAN,tr|A0A5H1ZRR1|A0A5H1ZRR1_HUMAN" 2 1003.6054 1.19 46801 12122 2 1003.605948 502.81 Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1 10.18 2789.1 - 778362 - - - 0.561 - 1.305 0.329 - 250.4 1 2 0 0.0006 9 0 0 0 2.73E+07 2.30E+07 - - - 2.241 0.9951 230117_WJC_METTL3_WT_vs_EV_F06.12127.12127.2 0.0961 16-Jun K.LVPVGYGIK[136.11].K sp|P24534|EF1B_HUMAN 1 952.5837 0.72 46803 12127 2 952.583919 477.2991 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2789.7 - 1.34E+06 - - - 0.2257 - 1.185 0.262 - 75.6 4 2 0 0.0002 9 0 0 0 1.22E+09 1.69E+09 - - - 1.1982 0.9959 230117_WJC_METTL3_WT_vs_EV_F06.12129.12129.2 0.0636 12-Jul K.VPVNLLR.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 809.5123 1.17 46805 12129 2 809.511942 405.7634 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2789.9 - 1.74E+06 - - - -0.4707 - 1.286 0.249 - 171.5 1 2 0 -0.0004 7 0 0 0 1.44E+08 1.23E+08 - - - 1.677 0.9949 230117_WJC_METTL3_WT_vs_EV_F06.12133.12133.2 0.00514 14-Aug R.VFVSPLAK[136.11].K "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 867.5309 0.75 46807 12133 2 867.529401 434.7727 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 8.72 2790.5 - 1.47E+06 - - - -1.774 - 1.51 0.266 - 192.2 1 2 0 -0.0015 8 0 0 0 3.11E+08 4.13E+08 - - - 2.2481 0.994 230117_WJC_METTL3_WT_vs_EV_F06.12134.12134.2 0.098 14-Aug R.LLEEGVLR.Q "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 927.5389 2.53 46808 12134 2 927.536899 464.7767 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 2790.6 - 1.10E+06 - - - -2.1918 - 1.528 0.274 - 152.6 1 2 0 -0.002 8 0 0 0 1.23E+08 4.85E+07 - - - 2.3428 0.999 230117_WJC_METTL3_WT_vs_EV_F06.12142.12142.2 0.0214 12-Aug R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.52 46811 12142 2 844.469636 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2791.6 - 4.98E+07 - - - 0.2143 - 1.565 0.3 - 199.2 1 2 0 0.0002 7 0 0 0 1.11E+10 7.30E+09 - - - 2.6759 0.9755 230117_WJC_METTL3_WT_vs_EV_F06.12144.12144.2 3.25 12-Jun K.IPVIIER.Y "sp|A6NCE7|MP3B2_HUMAN,sp|Q9GZQ8|MLP3B_HUMAN,sp|Q9H492|MLP3A_HUMAN,tr|H3BTL1|H3BTL1_HUMAN" 4 838.5276 1.38 46813 12144 2 838.528471 420.2711 Microtubule-associated proteins 1A\1B light chain 3 beta 2 OS=Homo sapiens OX=9606 GN=MAP1LC3B2 PE=2 SV=1 6 2791.8 - 784762 - - - 0.9922 - 1.311 0.027 - 130.5 3 2 0 0.0008 7 0 0 0 4.88E+07 3.54E+07 - - - -0.115 0.9427 230117_WJC_METTL3_WT_vs_EV_F06.12151.12151.2 0.625 14-Jul R.LLEEGVLR[166.11].Q "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 937.5472 2.59 46815 12151 2 937.545841 469.7809 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 2792.8 - 1.55E+06 - - - -1.4517 - 1.301 0.04 - 145.8 1 2 0 -0.0014 8 0 0 0 1.23E+08 4.74E+07 - - - 0.1296 0.9699 230117_WJC_METTL3_WT_vs_EV_F06.12155.12155.2 5.46 12-Jul R.YISGILR.K "sp|P46020|KPB1_HUMAN,sp|P46019|KPB2_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 4 820.4807 1.86 46816 12155 2 820.480603 411.2476 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 8.75 2793.3 - 1.10E+06 - - - -0.1048 - 1.198 0.055 - 149.5 1 2 0 -0.0001 7 0 0 0 8.08E+07 4.34E+07 - - - 0.0196 0.9954 230117_WJC_METTL3_WT_vs_EV_F06.12168.12168.2 1.64E-05 20-Oct R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 128.83 46821 12168 2 1264.624869 633.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2795.1 - 316270 - - - -4.0035 - 2.265 0.45 - 246.4 1 2 0 -0.0051 11 0 0 0 2.53E+07 1.96E+05 - - - 4.5748 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.12182.12182.2 0.104 16-Sep K.LVPVGYGIK.K sp|P24534|EF1B_HUMAN 1 944.5695 0.72 46825 12182 2 944.568908 473.292 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2797 - 1.59E+07 - - - -0.631 - 1.648 0.41 - 339.2 1 2 0 -0.0006 9 0 0 0 1.22E+09 1.69E+09 - - - 3.5143 0.9911 230117_WJC_METTL3_WT_vs_EV_F06.12203.12203.2 0.123 12-Jul K.LSIVPVR[166.11].R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 792.5097 0.87 46829 12203 2 792.50855 397.2621 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2800.1 - 2.58E+07 - - - -1.4435 - 1.496 0.165 - 179.4 1 2 0 -0.0011 7 0 0 0 2.52E+09 2.91E+09 - - - 1.5356 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.12204.12204.2 0.000222 14-Jul R.MVDFAGVK[136.11].D "sp|P21964|COMT_HUMAN,tr|E7EUU8|E7EUU8_HUMAN,tr|E7EMS6|E7EMS6_HUMAN,tr|F8WBW9|F8WBW9_HUMAN,tr|H7BZ45|H7BZ45_HUMAN,tr|A0A7I2V3G7|A0A7I2V3G7_HUMAN,tr|A0A7I2V370|A0A7I2V370_HUMAN" 7 873.451 1.27 46830 12204 2 873.454577 437.7328 Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT PE=1 SV=2 5.59 2800.3 - 532760 - - - 4.1239 - 1.544 0.411 - 106.6 1 2 0 0.0036 8 0 0 0 9.46E+07 7.45E+07 - - - 3.3856 0.9593 230117_WJC_METTL3_WT_vs_EV_F06.12225.12225.2 0.102 14-Jul K.TPVIVTLK[136.11].E "sp|Q9Y4L1|HYOU1_HUMAN,tr|A0A087WWI4|A0A087WWI4_HUMAN,tr|K7EQK2|K7EQK2_HUMAN,tr|A0A087WW13|A0A087WW13_HUMAN,tr|Q9BST8|Q9BST8_HUMAN,tr|J3KTF1|J3KTF1_HUMAN,tr|A0A494C039|A0A494C039_HUMAN,tr|J3QL06|J3QL06_HUMAN,tr|A0A087X214|A0A087X214_HUMAN,tr|A0A087X054|A0A087X054_HUMAN,tr|E9PJ21|E9PJ21_HUMAN,tr|J3QLE9|J3QLE9_HUMAN,tr|J3QQH7|J3QQH7_HUMAN" 13 877.5728 1.35 46837 12225 2 877.569816 439.7937 Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1 8.41 2803.1 - 317100 - - - -3.406 - 1.245 0.213 - 81 1 2 0 -0.003 8 0 0 0 1.36E+07 1.01E+07 - - - 1.2742 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.12238.12238.2 0.00805 16-Aug K.VLEGMEVVR[166.11].K "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1040.5564 0.16 46840 12238 2 1040.557578 521.2855 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.53 2805.1 - 402908 - - - 1.1455 - 1.641 0.193 - 212.2 1 2 0 0.0012 9 0 0 0 7.68E+06 4.84E+07 - - - 1.8991 0.9958 230117_WJC_METTL3_WT_vs_EV_F06.12241.12241.2 0.275 12-Jul K.LSIVPVR.R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 782.5014 0.87 46841 12241 2 782.501304 392.258 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2805.5 - 5.82E+07 - - - -0.1534 - 1.462 0.169 - 184.3 1 2 0 -0.0001 7 0 0 0 2.52E+09 2.91E+09 - - - 1.4926 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.12256.12256.2 0.0259 14-Jun R.SLFEQYGK.V "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 970.476 999 46849 12256 2 970.476262 486.2453 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.72 2807.3 - 408104 - - - 0.2731 - 1.241 0.35 - 102.2 1 2 0 0.0003 8 0 0 0 1.76E+07 0.00E+00 - - - 2.2772 0.9923 230117_WJC_METTL3_WT_vs_EV_F06.12258.12258.2 0.555 12-Jul K.GVTLGFR[166.11].Y "sp|P32969|RL9_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 4 758.4314 0.001 46851 12258 2 758.431743 380.223 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 9.75 2807.5 - 1.69E+06 - - - 0.3942 - 1.328 0.117 - 249 1 2 0 0.0003 7 0 0 0 0.00E+00 9.62E+07 - - - 0.8039 0.996 230117_WJC_METTL3_WT_vs_EV_F06.12264.12264.2 0.829 12-Jul R.YNSLLIR.H "sp|Q6ZNG0|ZN620_HUMAN,sp|Q6ZMY9|ZN517_HUMAN,tr|H0YCN3|H0YCN3_HUMAN" 3 877.5022 0.34 46854 12264 2 877.503788 439.7584 Zinc finger protein 620 OS=Homo sapiens OX=9606 GN=ZNF620 PE=1 SV=1 8.75 2808.2 - 227576 - - - 1.8644 - 1.351 0.163 - 128.2 1 2 0 0.0016 7 0 0 0 7.91E+06 2.35E+07 - - - 1.1976 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.12287.12287.2 0.0138 12-Aug R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.5 46860 12287 2 852.484772 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2811.7 - 4.99E+07 - - - 1.3103 - 1.537 0.297 - 205.8 1 2 0 0.0011 7 0 0 0 8.88E+09 5.91E+09 - - - 2.5962 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.12289.12289.2 0.0601 12-Jul K.YLYEIAR.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 926.4862 96.82 46861 12289 2 926.488052 464.2504 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6 2811.9 - 5.08E+06 - - - 2.0335 - 1.395 0.217 - 187.3 1 2 0 0.0019 7 0 0 0 8.17E+08 8.44E+06 - - - 1.698 0.8933 230117_WJC_METTL3_WT_vs_EV_F06.12311.12311.2 0.13 12-Jul F.ILEVYYK[136.11].S sp|A8MTT3|CEBOS_HUMAN 1 934.5255 5.24 46877 12311 2 934.526319 468.27 Protein CEBPZOS OS=Homo sapiens OX=9606 GN=CEBPZOS PE=1 SV=2 6 2814.5 - 426762 - - - 0.855 - 1.431 0.251 - 130.9 1 1 0 0.0008 7 0 0 0 1.43E+08 2.73E+07 - - - 2.0302 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.12335.12335.2 0.228 14-Aug R.LADIVVPR.G sp|Q9NWZ5|UCKL1_HUMAN 1 881.5335 3.83 46891 12335 2 881.535239 441.774 Uridine-cytidine kinase-like 1 OS=Homo sapiens OX=9606 GN=UCKL1 PE=1 SV=2 5.84 2817.6 - 465520 - - - 2.0271 - 1.755 0.277 - 188.3 1 2 0 0.0018 8 0 0 0 1.51E+07 3.93E+06 - - - 2.7827 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.12341.12341.2 0.00287 20-Jul R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 20.71 46893 12341 2 1201.61007 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2818.5 - 200532 - - - 0.7765 - 1.521 0.414 - 84.5 1 2 0 0.0009 11 0 0 0 8.06E+06 3.89E+05 - - - 3.233 0.9964 230117_WJC_METTL3_WT_vs_EV_F06.12365.12365.2 0.0213 12-Jul R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.52 46902 12365 2 844.470763 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2821.8 - 1.12E+07 - - - 1.5489 - 1.197 0.221 - 143.1 1 2 0 0.0013 7 0 0 0 1.11E+10 7.30E+09 - - - 1.2427 0.9916 230117_WJC_METTL3_WT_vs_EV_F06.12366.12366.2 0.688 14-Jun K.LIGEYGLR.N "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 919.5127 0.8 46903 12366 2 919.514981 460.7636 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 2821.9 - 961280 - - - 2.4622 - 1.232 0.155 - 78.4 1 2 0 0.0023 8 0 0 0 2.67E+09 3.32E+09 - - - 0.8144 0.857 230117_WJC_METTL3_WT_vs_EV_F06.12370.12370.2 0.0561 14-Jul A.LLPALAAR[166.11].G "sp|P46531|NOTC1_HUMAN,sp|Q86Y56|DAAF5_HUMAN,sp|P08582|TRFM_HUMAN,tr|A0A7P0T8U6|A0A7P0T8U6_HUMAN,tr|A0A7P0TAK8|A0A7P0TAK8_HUMAN,tr|A0A7P0TB20|A0A7P0TB20_HUMAN,tr|A0A7P0T8W1|A0A7P0T8W1_HUMAN,tr|A0A7P0Z4H9|A0A7P0Z4H9_HUMAN,tr|A0A7P0T9V1|A0A7P0T9V1_HUMAN,tr|A0A7P0TBG2|A0A7P0TBG2_HUMAN" 10 833.5362 1.24 46905 12370 2 833.537256 417.7754 Neurogenic locus notch homolog protein 1 OS=Homo sapiens OX=9606 GN=NOTCH1 PE=1 SV=4 9.75 2822.4 - 917487 - - - 1.2153 - 1.376 0.227 - 142.1 1 1 0 0.001 8 0 0 0 4.36E+07 3.51E+07 - - - 1.6799 0.9927 230117_WJC_METTL3_WT_vs_EV_F06.12374.12374.2 1.29 12-Jul R.LLSVNIR.V sp|P07814|SYEP_HUMAN 1 813.5072 1.46 46906 12374 2 813.507883 407.7609 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 9.75 2822.9 - 491894 - - - 0.7929 - 1.234 0.141 - 115.6 1 2 0 0.0006 7 0 0 0 2.21E+08 1.52E+08 - - - 0.7484 0.8648 230117_WJC_METTL3_WT_vs_EV_F06.12391.12391.2 0.00207 16-Sep R.PLISVYSEK.G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1034.5648 0.76 46912 12391 2 1034.569271 518.2897 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.42 2825.4 - 850345 - - - 4.31 - 1.595 0.404 - 298.9 1 1 0 0.0045 9 0 0 0 4.64E+07 6.09E+07 - - - 3.3742 0.9936 230117_WJC_METTL3_WT_vs_EV_F06.12410.12410.2 0.199 18-Jul K.QYGNEVFLAK.L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1167.5924 19.38 46917 12410 2 1167.594842 584.8035 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6 2828.1 - 130655 - - - 2.0709 - 1.29 0.154 - 154.6 1 2 0 0.0024 10 0 0 0 1.08E+07 5.57E+05 - - - 0.8885 0.8907 230117_WJC_METTL3_WT_vs_EV_F06.12428.12428.2 1.21 20-Jun R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 999 46922 12428 2 1068.660679 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 2830.6 - 1.20E+06 - - - 5.9729 - 1.36 0.121 - 74.3 3 2 0 0.0064 11 0 0 0 4.03E+07 0.00E+00 - - - 0.5514 0.9887 230117_WJC_METTL3_WT_vs_EV_F06.12435.12435.2 0.179 14-May K.QYFEQFGK[136.11].V "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|J3KTC1|J3KTC1_HUMAN" 7 1053.5011 1.47 46926 12435 2 1053.50336 527.7578 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6 2831.5 - 85718.7 - - - 2.149 - 1.025 0.187 - 63 1 2 0 0.0023 8 0 0 0 4.48E+06 3.05E+06 - - - 0.4959 0.9602 230117_WJC_METTL3_WT_vs_EV_F06.12455.12455.2 3.36 12-Jun K.TC[160.03]PLLLR[166.11].V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 881.5032 1.26 46934 12455 2 881.502405 441.7589 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2834.3 - 544797 - - - -0.9348 - 1.132 0.099 - 118.4 1 2 0 -0.0008 7 0 0 0 1.20E+09 9.48E+08 - - - 0.1648 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.12456.12456.2 2.08E-05 18-Sep K.DVNAAIATIK.T "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 8 1014.571 6.03 46935 12456 2 1014.571563 508.2928 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 5.84 2834.4 - 228612 - - - 0.5943 - 1.715 0.492 - 144.7 1 2 0 0.0006 10 0 0 0 1.92E+07 3.19E+06 - - - 4.1804 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.12467.12467.2 0.0286 12-Jun K.TC[160.03]PLLLR.V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 871.495 1.26 46940 12467 2 871.494696 436.7548 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2835.8 - 1.01E+06 - - - -0.3018 - 1.355 0.294 - 165.9 1 2 0 -0.0003 7 0 0 0 1.19E+09 9.48E+08 - - - 2.175 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.12479.12479.4 1.50E-05 16/108 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 3.44 46946 12479 4 2080.027852 521.0129 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2837.3 - 673137 - - - 2.5572 - 2.378 0.443 - 47.4 1 2 0 0.0053 19 0 0 0 2.82E+07 8.20E+06 - - - 3.3734 0.997 230117_WJC_METTL3_WT_vs_EV_F06.12490.12490.2 0.706 14-Aug R.LPLQDVYK[136.11].L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 982.5579 5.18 46950 12490 2 982.560464 492.2862 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2838.8 - 667170 - - - 2.6268 - 1.678 0.15 - 210.9 1 2 0 0.0026 8 0 0 0 2.29E+09 4.43E+08 - - - 1.7092 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.12505.12505.3 2.35E-06 Dec-72 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 48.7 46955 12505 3 2080.027664 694.3481 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2840.9 - 227276 - - - 2.4668 - 2.182 0.498 - 51.6 1 2 0 0.0051 19 0 0 0 7.93E+07 1.63E+06 - - - 6.0077 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.12510.12510.2 0.000117 18-Sep R.TIAQDYGVLK.A "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1106.5972 1.33 46957 12510 2 1106.600697 554.3059 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.5 2841.5 - 184644 - - - 3.1827 - 1.718 0.45 - 181.3 1 2 0 0.0035 10 0 0 0 1.16E+07 8.76E+06 - - - 3.8741 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.12515.12515.2 0.00355 18-Sep R.SINQPVAFVR.R "sp|Q9GZT3|SLIRP_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|H0YJI1|H0YJI1_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1129.6244 1.14 46961 12515 2 1129.62713 565.8195 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 9.47 2842.1 - 138893 - - - 2.4229 - 1.939 0.424 - 216.7 1 2 0 0.0027 10 0 0 0 5.60E+06 4.89E+06 - - - 4.0201 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.12520.12520.2 0.0406 12-Aug R.WLGEPIK[136.11].A "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 849.484 0.46 46963 12520 2 849.486242 425.7493 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6 2842.8 - 2.23E+06 - - - 2.651 - 1.306 0.311 - 285.7 1 2 0 0.0023 7 0 0 0 1.12E+09 2.42E+09 - - - 2.1832 0.999 230117_WJC_METTL3_WT_vs_EV_F06.12526.12526.2 0.068 14-Aug R.LPLQDVYK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 974.5437 5.22 46966 12526 2 974.545429 488.2791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2843.5 - 9.44E+06 - - - 1.7916 - 1.652 0.256 - 289.8 1 2 0 0.0017 8 0 0 0 2.31E+09 4.43E+08 - - - 2.4452 0.9486 230117_WJC_METTL3_WT_vs_EV_F06.12540.12540.2 2.32 12-May R.GDIQTLK[136.11].N sp|Q9HC62|SENP2_HUMAN 1 781.4425 1.1 46973 12540 2 781.442843 391.7285 Sentrin-specific protease 2 OS=Homo sapiens OX=9606 GN=SENP2 PE=1 SV=3 5.84 2845.2 - 1.00E+07 - - - 0.4146 - 1.169 0.014 - 150.2 2 2 0 0.0003 7 0 0 0 5.50E+08 4.98E+08 - - - -0.4954 0.9928 230117_WJC_METTL3_WT_vs_EV_F06.12547.12547.2 0.503 12-Jun R.WLGEPIK.A "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 841.4698 0.45 46975 12547 2 841.470756 421.7422 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6 2846.2 - 5.82E+06 - - - 1.148 - 1.054 0.204 - 174.2 1 2 0 0.001 7 0 0 0 1.08E+09 2.40E+09 - - - 0.7141 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.12548.12548.2 0.00279 16-Aug R.LYEALTPVH.- "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1041.5495 - 46976 12548 2 1041.551162 521.782 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.24 2846.4 - 429036 - - - 1.5995 - 1.422 0.41 - 175 1 2 0 0.0017 9 0 0 0 - - - - - 3.0873 0.9883 230117_WJC_METTL3_WT_vs_EV_F06.12565.12565.2 1.22 14-Jul K.IPYTTVLR.L "sp|Q08945|SSRP1_HUMAN,tr|E9PMD4|E9PMD4_HUMAN" 2 961.5597 0.26 46983 12565 2 961.560172 481.7871 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 8.75 2848.6 - 306999 - - - 0.5252 - 1.229 0.109 - 145.7 1 2 0 0.0005 8 0 0 0 1.13E+08 4.38E+08 - - - 0.4678 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.12572.12572.2 0.0114 12-May R.LVVFDAR[166.11].- sp|P53803|RPAB4_HUMAN 1 828.4733 1.04 46987 12572 2 828.47338 415.2439 "DNA-directed RNA polymerases I, II, and III subunit RPABC4 OS=Homo sapiens OX=9606 GN=POLR2K PE=1 SV=1" 5.84 2849.4 - 6.65E+06 - - - 0.0869 - 1.259 0.37 - 107.7 1 2 0 0.0001 7 0 0 0 3.13E+08 3.00E+08 - - - 2.5036 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.12582.12582.2 0.0365 20-Jul R.TAAENDFVTLK.K sp|P35908|K22E_HUMAN 1 1207.6085 18.06 46989 12582 2 1207.610375 604.8115 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2850.9 - 168572 - - - 1.5792 - 1.558 0.317 - 154.1 1 2 0 0.0019 11 0 0 0 5.43E+06 3.01E+05 - - - 2.5813 0.9214 230117_WJC_METTL3_WT_vs_EV_F06.12588.12588.2 0.0055 12-Oct L.PLQDVYK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 861.4596 2.59 46993 12588 2 861.460331 431.7371 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.26 2851.6 - 436174 - - - 0.8265 - 1.738 0.214 - 334.6 1 1 0 0.0007 7 0 0 0 2.41E+07 9.30E+06 - - - 2.3728 0.9912 230117_WJC_METTL3_WT_vs_EV_F06.12607.12607.2 0.111 16-Sep K.AGLAPLEVR.V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 924.5393 0.78 47002 12607 2 924.539236 463.2769 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.05 2854.1 - 435360 - - - -0.0324 - 1.585 0.065 - 186.5 1 2 0 0 9 0 0 0 9.13E+07 1.17E+08 - - - 0.8536 0.999 230117_WJC_METTL3_WT_vs_EV_F06.12611.12611.2 0.0185 16-Sep K.AGLAPLEVR[166.11].V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 934.5475 1.02 47003 12611 2 934.548414 468.281 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.05 2854.7 - 518528 - - - 0.9395 - 1.724 0.244 - 196.2 1 2 0 0.0009 9 0 0 0 7.61E+07 7.43E+07 - - - 2.4186 0.9752 230117_WJC_METTL3_WT_vs_EV_F06.12618.12618.2 4.46 16-May K.LVPVGYGIR[166.11].K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 982.5839 0.95 47006 12618 2 982.586264 492.2992 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2855.6 - 5.34E+06 - - - 2.3835 - 1.114 0.11 - 75.3 2 2 0 0.0023 9 0 0 0 7.48E+08 7.92E+08 - - - 0.0306 0.9934 230117_WJC_METTL3_WT_vs_EV_F06.12636.12636.2 0.00932 12-Jul R.FAAFIDK.V "sp|Q14533|KRT81_HUMAN,sp|P78386|KRT85_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|U3KPR1|U3KPR1_HUMAN" 6 810.4276 61.29 47015 12636 2 810.427528 406.2211 "Keratin, type II cuticular Hb1 OS=Homo sapiens OX=9606 GN=KRT81 PE=1 SV=3" 5.84 2857.9 - 2.12E+06 - - - -0.0765 - 1.443 0.12 - 145 1 2 0 -0.0001 7 0 0 0 9.26E+07 1.51E+06 - - - 1.0893 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.12639.12639.2 0.0101 16-Sep K.IGPLGLSPK.K sp|P30050|RL12_HUMAN 1 880.5382 1.62 47016 12639 2 880.538287 441.2764 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2858.3 - 8.85E+06 - - - 0.0954 - 1.63 0.358 - 239.5 1 2 0 0.0001 9 0 0 0 1.22E+10 7.57E+09 - - - 3.0987 0.986 230117_WJC_METTL3_WT_vs_EV_F06.12647.12647.2 0.181 16-Aug K.LVPVGYGIR.K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 972.5757 0.94 47018 12647 2 972.575201 487.2951 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2859.4 - 1.38E+07 - - - -0.4637 - 1.522 0.06 - 228.5 1 2 0 -0.0005 9 0 0 0 7.51E+08 7.96E+08 - - - 0.6992 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.12648.12648.2 0.0183 18-Sep R.RVLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1125.687 1.39 47019 12648 2 1125.688918 563.8508 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2859.6 - 289768 - - - 1.7101 - 1.827 0.252 - 199.4 1 2 0 0.0019 10 0 0 0 4.74E+07 3.41E+07 - - - 2.5839 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.12653.12653.2 0.174 12-Jul R.LAILYAK.R "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 790.4953 1.17 47021 12653 2 790.495597 396.2549 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 8.59 2860.2 - 1.22E+06 - - - 0.4061 - 1.691 0.219 - 164 1 2 0 0.0003 7 0 0 0 2.52E+08 2.16E+08 - - - 2.3229 0.9942 230117_WJC_METTL3_WT_vs_EV_F06.12654.12654.2 1 14-Sep R.LGNSLLLK.Y sp|Q10570|CPSF1_HUMAN 1 856.5382 0.05 47022 12654 2 856.538167 429.2764 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 2860.3 - 1.04E+06 - - - -0.042 - 1.439 0.141 - 147.1 1 2 0 0 8 0 0 0 1.17E+08 2.38E+09 - - - 1.1801 0.9579 230117_WJC_METTL3_WT_vs_EV_F06.12667.12667.2 1.04 12-Jul R.TLQVLIK.Q "sp|Q7Z3B4|NUP54_HUMAN,sp|P35219|CAH8_HUMAN" 2 813.5324 2.44 47027 12667 2 813.531932 407.7735 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.41 2861.9 - 2.21E+06 - - - -0.563 - 1.266 0.025 - 180.2 1 2 0 -0.0005 7 0 0 0 1.83E+08 7.49E+07 - - - -0.0272 0.9741 230117_WJC_METTL3_WT_vs_EV_F06.12674.12674.2 14.1 12-May K.LTATIWK[136.11].N sp|O15226|NKRF_HUMAN 1 839.4996 1.57 47028 12674 2 839.498669 420.7571 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 8.75 2863 - 1.84E+06 - - - -1.1566 - 1.269 0.104 - 57.1 1 2 0 -0.001 7 0 0 0 1.02E+08 6.53E+07 - - - 0.5637 0.9909 230117_WJC_METTL3_WT_vs_EV_F06.12675.12675.2 2.63 12-Jul R.LLASLYR[166.11].D sp|P57740|NU107_HUMAN 1 844.5046 0.05 47029 12675 2 844.504787 423.2596 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 8.75 2863.1 - 1.47E+06 - - - 0.2108 - 1.568 0.037 - 136.9 1 2 0 0.0002 7 0 0 0 1.11E+07 2.04E+08 - - - 0.7394 0.9726 230117_WJC_METTL3_WT_vs_EV_F06.12692.12692.2 2.25 20-Jun R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 999 47033 12692 2 1068.659006 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 2865.6 - 7.48E+06 - - - 4.4074 - 1.44 0.11 - 91.3 1 2 0 0.0047 11 0 0 0 6.86E+08 0.00E+00 - - - 0.8384 0.9625 230117_WJC_METTL3_WT_vs_EV_F06.12697.12697.2 2.25 12-Jun K.FLEPTLR.L "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 874.4913 1.03 47036 12697 2 874.491092 438.2529 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 2866.1 - 1.27E+06 - - - -0.1841 - 1.316 0.017 - 138.2 2 2 0 -0.0002 7 0 0 0 3.69E+08 3.57E+08 - - - -0.0979 0.9856 230117_WJC_METTL3_WT_vs_EV_F06.12727.12727.2 0.133 14-Jul K.FGELVMTK.E "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 923.4786 2.98 47044 12727 2 923.478108 462.7466 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6 2870.4 - 1.31E+06 - - - -0.5761 - 1.035 0.214 - 115.5 1 2 0 -0.0005 8 0 0 0 1.78E+08 6.00E+07 - - - 0.7252 0.9892 230117_WJC_METTL3_WT_vs_EV_F06.12728.12728.2 3.66 14-Sep R.LPVDIAYK.R sp|P15924|DESP_HUMAN 1 917.5222 6.04 47045 12728 2 917.520934 459.7684 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.83 2870.6 - 1.66E+06 - - - -1.4005 - 1.495 0.148 - 251.2 1 2 0 -0.0013 8 0 0 0 3.04E+08 5.03E+07 - - - 1.3465 0.9939 230117_WJC_METTL3_WT_vs_EV_F06.12734.12734.4 0.0555 15/96 T.LLLIILTDVFIISTVLR.L sp|Q8NGY0|O10X1_HUMAN 1 1941.2278 130.64 47046 12734 4 1941.22889 486.3142 Olfactory receptor 10X1 OS=Homo sapiens OX=9606 GN=OR10X1 PE=3 SV=2 5.84 2871.5 - 1.77E+06 - - - 0.5502 - 2.091 0.385 - 51.7 1 1 0 0.0011 17 0 0 0 9.21E+07 7.05E+05 - - - 2.8329 0.8852 230117_WJC_METTL3_WT_vs_EV_F06.12739.12739.2 0.18 14-Sep D.IADIEALK.E "sp|Q70CQ2|UBP34_HUMAN,sp|O75792|RNH2A_HUMAN,tr|A0A2R8Y606|A0A2R8Y606_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 4 871.5015 1.7 47049 12739 2 871.501238 436.758 Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens OX=9606 GN=USP34 PE=1 SV=2 4.37 2871.9 - 4.36E+06 - - - -0.2823 - 1.869 0.206 - 227.1 1 1 0 -0.0002 8 0 0 0 3.14E+08 1.85E+08 - - - 2.4486 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.12741.12741.2 0.354 14-Sep K.TALLGLTK[136.11].T sp|Q9BTZ2|DHRS4_HUMAN 1 823.5259 0.94 47050 12741 2 823.526844 412.7702 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 8.41 2872.2 - 1.45E+07 - - - 1.2021 - 1.529 0.204 - 344.2 1 2 0 0.001 8 0 0 0 6.93E+08 7.41E+08 - - - 1.828 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.12752.12752.2 0.0465 14-Aug K.FGELVMTK[136.11].E "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 931.4928 2.99 47056 12752 2 931.49282 466.7537 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6 2873.5 - 1.49E+06 - - - -0.0215 - 1.384 0.245 - 159.7 1 2 0 0 8 0 0 0 1.82E+08 6.09E+07 - - - 1.8307 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.12760.12760.2 0.0176 16-Sep K.IGPLGLSPK[136.11].K sp|P30050|RL12_HUMAN 1 888.5524 1.62 47060 12760 2 888.551839 445.2835 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2874.5 - 6.67E+07 - - - -0.6347 - 1.771 0.258 - 233.5 1 2 0 -0.0006 9 0 0 0 1.22E+10 7.54E+09 - - - 2.5999 0.9675 230117_WJC_METTL3_WT_vs_EV_F06.12775.12775.2 7.76 14-Jun K.ILGDLSYR.S "sp|Q9NVC6|MED17_HUMAN,tr|A0A1W2PNF3|A0A1W2PNF3_HUMAN,tr|E9PM72|E9PM72_HUMAN,tr|A0A1W2PQ48|A0A1W2PQ48_HUMAN,tr|A0A1W2PS27|A0A1W2PS27_HUMAN,tr|A0A1W2PR99|A0A1W2PR99_HUMAN,tr|A0A1W2PRB8|A0A1W2PRB8_HUMAN,tr|A0A1W2PPP8|A0A1W2PPP8_HUMAN,tr|A0A1W2PNW7|A0A1W2PNW7_HUMAN,tr|A0A1W2PS69|A0A1W2PS69_HUMAN,tr|A0A1W2PRX4|A0A1W2PRX4_HUMAN" 11 935.5076 1.37 47066 12775 2 935.507997 468.7611 Mediator of RNA polymerase II transcription subunit 17 OS=Homo sapiens OX=9606 GN=MED17 PE=1 SV=2 5.84 2876.7 - 779904 - - - 0.3902 - 1.077 0.074 - 74.8 1 2 0 0.0004 8 0 0 0 2.00E+07 1.46E+07 - - - -0.1888 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.12786.12786.2 0.118 18-Dec R.ISGLIYEETR[166.11].G sp|P62805|H4_HUMAN 1 1189.6218 0.64 47070 12786 2 1189.62246 595.8182 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2878.1 - 430982 - - - 0.5355 - 2.473 0.312 - 506.7 1 2 0 0.0006 10 0 0 0 7.62E+06 1.19E+07 - - - 3.8726 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.12797.12797.2 0.00416 18-Oct R.ISGLIYEETR.G sp|P62805|H4_HUMAN 1 1179.6136 0.64 47075 12797 2 1179.613057 590.8141 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2879.5 - 279778 - - - -0.4205 - 2.156 0.385 - 308.6 1 2 0 -0.0005 10 0 0 0 7.62E+06 1.19E+07 - - - 4.0289 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.12810.12810.3 0.0529 Sep-36 R.LVNHFVEEFK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1260.6503 18.87 47081 12810 3 1260.652542 421.224 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2881.2 - 3.29E+06 - - - 1.7999 - 1.754 0.257 - 97.9 1 2 0 0.0023 10 0 0 0 1.98E+08 1.05E+07 - - - 3.0457 0.8742 230117_WJC_METTL3_WT_vs_EV_F06.12811.12811.2 3.21 14-Apr R.ILLVGEPR[166.11].V "sp|Q8IXI2|MIRO1_HUMAN,tr|J3KSR5|J3KSR5_HUMAN" 2 905.5574 1.83 47082 12811 2 905.559721 453.786 Mitochondrial Rho GTPase 1 OS=Homo sapiens OX=9606 GN=RHOT1 PE=1 SV=2 6 2881.3 - 146783 - - - 2.594 - 1.025 0.07 - 27.8 24 2 0 0.0023 8 0 0 0 2.16E+07 1.19E+07 - - - -0.9848 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.12823.12823.2 0.197 20-Sep K.LIADVAPSAIR[166.11].E "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1134.6636 1.51 47087 12823 2 1134.664439 568.3391 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 5.84 2882.9 - 95120.3 - - - 0.7139 - 1.408 0.224 - 217.2 1 2 0 0.0008 11 0 0 0 2.98E+07 1.98E+07 - - - 1.6209 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.12829.12829.2 0.0594 14-Aug K.QVEELFER[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1058.5272 1.93 47090 12829 2 1058.529546 530.2709 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2883.6 - 354256 - - - 2.221 - 1.721 0.286 - 301.1 1 2 0 0.0024 8 0 0 0 2.40E+07 1.25E+07 - - - 2.79 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.12831.12831.2 0.00492 18-Sep R.LGPSVVGLAR.Y "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 967.5815 1.44 47092 12831 2 967.583826 484.798 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 9.75 2883.9 - 670196 - - - 2.4401 - 1.727 0.213 - 236.1 1 2 0 0.0024 10 0 0 0 8.51E+07 5.92E+07 - - - 2.1386 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.12836.12836.2 0.0631 20-Jul K.LIADVAPSAIR.E "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1124.6554 1.51 47095 12836 2 1124.658737 563.335 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 5.84 2884.5 - 279653 - - - 3.0036 - 1.449 0.313 - 140.2 1 2 0 0.0034 11 0 0 0 3.00E+07 1.99E+07 - - - 2.3551 0.9961 230117_WJC_METTL3_WT_vs_EV_F06.12842.12842.2 0.0065 14-Jul K.FQNALLVR.Y "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 959.5553 489.36 47097 12842 2 959.55881 480.7849 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 9.75 2885.4 - 170426 - - - 3.7101 - 1.298 0.304 - 136.4 1 2 0 0.0036 8 0 0 0 1.19E+08 2.44E+05 - - - 2.0719 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.12844.12844.4 7.37E-05 14/198 R.SDSPVPTAPTSGGPKPSTASAVPELATDPELEKK.L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3360.6937 999 47098 12844 4 3360.707068 841.1807 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2885.6 - 233304 - - - 3.9894 - 2.335 0.383 - 73.2 1 2 0 0.0134 34 0 0 0 1.20E+07 0.00E+00 - - - 2.8088 0.9945 230117_WJC_METTL3_WT_vs_EV_F06.12846.12846.2 9.18 16-Sep K.AIPLALEGK[136.11].D "sp|Q9NY93|DDX56_HUMAN,tr|F8WDT8|F8WDT8_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|F8WEI3|F8WEI3_HUMAN" 4 918.563 1.11 47100 12846 2 918.564884 460.2888 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 6.05 2885.8 - 604584 - - - 2.0859 - 1.292 0.166 - 144.3 1 2 0 0.0019 9 0 0 0 2.61E+07 2.34E+07 - - - 1.0076 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.12856.12856.2 0.237 12-Jul R.VFLQQLK.G "sp|Q13487|SNPC2_HUMAN,tr|M0QXY9|M0QXY9_HUMAN" 2 874.5276 0.06 47105 12856 2 874.529407 438.2711 snRNA-activating protein complex subunit 2 OS=Homo sapiens OX=9606 GN=SNAPC2 PE=1 SV=1 8.72 2887 - 419512 - - - 2.0217 - 1.444 0.238 - 134.6 1 2 0 0.0018 7 0 0 0 1.20E+07 2.10E+08 - - - 1.9625 0.9148 230117_WJC_METTL3_WT_vs_EV_F06.12857.12857.2 5.97 14-Jun K.LISGWVSR.S "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 916.5131 1.2 47106 12857 2 916.518098 459.2638 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 9.75 2887.1 - 1.02E+06 - - - 5.5067 - 1.143 0.146 - 79.4 1 2 0 0.005 8 0 0 0 4.34E+07 3.63E+07 - - - 0.5209 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.12859.12859.2 0.0164 16-Sep K.AFADPEVLR.R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1016.5291 2.4 47108 12859 2 1016.533004 509.2718 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2887.3 - 360333 - - - 3.8454 - 1.559 0.306 - 309.7 1 2 0 0.0039 9 0 0 0 7.71E+07 3.21E+07 - - - 2.5845 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.12865.12865.2 2.17 16-Oct K.AIPLALEGK.D "sp|Q9NY93|DDX56_HUMAN,tr|F8WDT8|F8WDT8_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|F8WEI3|F8WEI3_HUMAN" 4 910.5488 1.13 47112 12865 2 910.5512 456.2817 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 6.05 2888 - 496159 - - - 2.6709 - 1.696 0.147 - 318.5 1 2 0 0.0024 9 0 0 0 2.75E+07 2.43E+07 - - - 1.6543 0.9937 230117_WJC_METTL3_WT_vs_EV_F06.12874.12874.2 1.07 14-Aug R.ILLVGEPR.V "sp|Q8IXI2|MIRO1_HUMAN,tr|J3KSR5|J3KSR5_HUMAN" 2 895.5491 1.59 47118 12874 2 895.551375 448.7818 Mitochondrial Rho GTPase 1 OS=Homo sapiens OX=9606 GN=RHOT1 PE=1 SV=2 6 2889 - 439081 - - - 2.5381 - 1.618 0.076 - 202.9 1 2 0 0.0023 8 0 0 0 2.41E+07 1.52E+07 - - - 1.0529 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.12881.12881.2 0.00135 16-Aug K.AFADPEVLR[166.11].R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1026.5374 2.39 47121 12881 2 1026.540734 514.276 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2889.9 - 558885 - - - 3.2819 - 1.525 0.378 - 234.5 1 2 0 0.0034 9 0 0 0 7.71E+07 3.22E+07 - - - 3.0527 1 230117_WJC_METTL3_WT_vs_EV_F06.12883.12883.2 2.07E-07 26-Nov R.LVPGGGATEIELAK.Q sp|P50990|TCPQ_HUMAN 1 1353.7504 24.51 47123 12883 2 1353.752155 677.8825 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 2890.2 - 188157 - - - 1.3104 - 2.279 0.556 - 186.5 1 2 0 0.0018 14 0 0 0 3.82E+07 1.56E+06 - - - 5.2142 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.12891.12891.2 0.025 16-Jul R.LVPLVNGVR.E "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 965.6022 2.89 47127 12891 2 965.604078 483.8084 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 9.75 2891.2 - 1.78E+06 - - - 1.9439 - 1.573 0.331 - 194.3 1 2 0 0.0019 9 0 0 0 1.45E+08 5.01E+07 - - - 2.7957 0.9872 230117_WJC_METTL3_WT_vs_EV_F06.12905.12905.2 1.17 14-Aug K.LLGGLAVR.R "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|H0YF32|H0YF32_HUMAN" 5 797.5123 1.72 47134 12905 2 797.512427 399.7634 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 9.75 2893 - 9.92E+06 - - - 0.1304 - 1.404 0.062 - 167.5 1 2 0 0.0001 8 0 0 0 5.13E+09 2.99E+09 - - - 0.5223 0.9486 230117_WJC_METTL3_WT_vs_EV_F06.12931.12931.2 4.29 12-Jul K.TVYSILR[166.11].H "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 860.4995 0.46 47144 12931 2 860.499439 431.257 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 8.41 2896.6 - 1.65E+06 - - - -0.0976 - 1 0.084 - 180.5 1 2 0 -0.0001 7 0 0 0 1.31E+08 2.85E+08 - - - -0.3386 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.12932.12932.2 0.0921 14-Jul K.GYGFGMVK[136.11].L "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RFL1|E5RFL1_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 6 865.4248 1.15 47145 12932 2 865.425315 433.7197 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 8.59 2896.7 - 538059 - - - 0.6413 - 1.133 0.313 - 72.7 1 2 0 0.0006 8 0 0 0 2.56E+07 2.22E+07 - - - 1.7292 0.9968 230117_WJC_METTL3_WT_vs_EV_F06.12936.12936.2 1.04 12-Jun K.ELVTLYR.R sp|Q8TD55|PKHO2_HUMAN 1 892.5018 1.34 47147 12936 2 892.502881 447.2582 Pleckstrin homology domain-containing family O member 2 OS=Homo sapiens OX=9606 GN=PLEKHO2 PE=1 SV=1 6.1 2897.2 - 988782 - - - 1.191 - 1.351 0.18 - 168.3 1 2 0 0.0011 7 0 0 0 3.55E+07 2.64E+07 - - - 1.3234 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.12938.12938.2 0.199 12-Aug R.VAIFIEK.T sp|Q9P258|RCC2_HUMAN 1 818.4902 1.63 47148 12938 2 818.490536 410.2524 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2897.4 - 1.66E+06 - - - 0.4215 - 1.632 0.213 - 232.7 1 2 0 0.0003 7 0 0 0 8.83E+07 5.40E+07 - - - 2.1661 0.9347 230117_WJC_METTL3_WT_vs_EV_F06.12939.12939.2 1.27 12-May K.FYVEDLK.A "sp|O75400|PR40A_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 2 912.4593 0.9 47149 12939 2 912.458605 457.2369 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 4.37 2897.6 - 498178 - - - -0.7441 - 0.924 0.148 - 53.9 2 2 0 -0.0007 7 0 0 0 1.79E+07 1.98E+07 - - - -0.251 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.12940.12940.2 0.0376 16-Aug K.MLVVGGIDR.V sp|Q15046|SYK_HUMAN 1 958.527 1.22 47150 12940 2 958.527941 480.2708 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2897.6 - 2.54E+06 - - - 0.9953 - 1.628 0.323 - 303.2 1 2 0 0.001 9 0 0 0 1.69E+08 1.39E+08 - - - 2.8363 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.12943.12943.2 0.399 12-Aug R.VAIFIEK[136.11].T sp|Q9P258|RCC2_HUMAN 1 826.5044 1.65 47152 12943 2 826.504794 414.2595 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2898 - 1.22E+06 - - - 0.4876 - 1.987 0.144 - 230.9 1 2 0 0.0004 7 0 0 0 8.83E+07 5.37E+07 - - - 2.2801 0.9968 230117_WJC_METTL3_WT_vs_EV_F06.12946.12946.2 0.579 16-Jun K.MLVVGGIDR[166.11].V sp|Q15046|SYK_HUMAN 1 968.5353 1.21 47153 12946 2 968.535319 485.2749 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2898.4 - 2.65E+06 - - - 0.064 - 1.536 0.181 - 167.8 1 2 0 0.0001 9 0 0 0 1.68E+08 1.39E+08 - - - 1.6195 0.9839 230117_WJC_METTL3_WT_vs_EV_F06.12952.12952.2 0.632 12-Jul K.ILEVDLK[136.11].N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 836.5099 0.88 47155 12952 2 836.508565 419.2622 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2899.2 - 667244 - - - -1.5601 - 1.569 0.087 - 116.6 1 2 0 -0.0013 7 0 0 0 1.52E+08 1.72E+08 - - - 1.1104 0.9913 230117_WJC_METTL3_WT_vs_EV_F06.12954.12954.2 0.316 14-Jun R.ALEGLVYR.S "sp|Q9Y4R8|TELO2_HUMAN,tr|H3BU45|H3BU45_HUMAN" 2 919.5127 2.99 47156 12954 2 919.512098 460.7636 Telomere length regulation protein TEL2 homolog OS=Homo sapiens OX=9606 GN=TELO2 PE=1 SV=2 6.05 2899.4 - 818350 - - - -0.6732 - 1.421 0.161 - 108.8 2 2 0 -0.0006 8 0 0 0 4.65E+07 1.56E+07 - - - 1.1552 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.12971.12971.2 0.241 12-Jun R.QVAIVFR.T "sp|Q04206|TF65_HUMAN,tr|A0A087X0W8|A0A087X0W8_HUMAN,tr|E9PKH5|E9PKH5_HUMAN,tr|Q2TAM5|Q2TAM5_HUMAN" 4 831.4967 3.91 47161 12971 2 831.496704 416.7556 Transcription factor p65 OS=Homo sapiens OX=9606 GN=RELA PE=1 SV=2 9.75 2901.8 - 2.17E+06 - - - 0.0373 - 1.3 0.301 - 121 1 2 0 0 7 0 0 0 9.63E+07 2.46E+07 - - - 2.0955 0.991 230117_WJC_METTL3_WT_vs_EV_F06.12980.12980.2 0.451 14-Jul K.FIINSYPK[136.11].Y "sp|Q96EY7|PTCD3_HUMAN,tr|B8ZZQ4|B8ZZQ4_HUMAN" 2 988.5473 0.97 47166 12980 2 988.54644 495.2809 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 8.59 2902.8 - 227585 - - - -0.8882 - 1.14 0.243 - 92.4 1 2 0 -0.0009 8 0 0 0 1.56E+07 1.61E+07 - - - 1.2307 0.9784 230117_WJC_METTL3_WT_vs_EV_F06.13004.13004.2 1.23 12-Jun R.LSSFIVK.E sp|P24278|ZBT25_HUMAN 1 792.4745 0.84 47173 13004 2 792.474734 397.2445 Zinc finger and BTB domain-containing protein 25 OS=Homo sapiens OX=9606 GN=ZBTB25 PE=1 SV=2 8.75 2906.2 - 1.14E+06 - - - 0.2435 - 1.216 0.099 - 75.7 4 2 0 0.0002 7 0 0 0 5.35E+07 6.36E+07 - - - 0.1229 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.13017.13017.2 1.76 14-Jul R.QMAAVLLR[166.11].R "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 11 910.5298 1.07 47182 13017 2 910.53058 456.2722 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 2907.8 - 1.03E+06 - - - 0.8808 - 1.613 0.155 - 162.1 1 2 0 0.0008 8 0 0 0 5.97E+07 5.56E+07 - - - 1.6275 0.9934 230117_WJC_METTL3_WT_vs_EV_F06.13027.13027.2 0.0231 14-Jul K.LTPVLLAK[136.11].Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 861.5779 1.73 47188 13027 2 861.577783 431.7962 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2909.1 - 4.10E+06 - - - -0.1242 - 1.17 0.216 - 140.7 1 2 0 -0.0001 8 0 0 0 3.30E+08 1.90E+08 - - - 1.1099 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.13032.13032.2 0.0113 14-Sep K.VVLVLAGR[166.11].Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 835.5519 0.77 47190 13032 2 835.554046 418.7832 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2909.8 - 3.99E+06 - - - 2.5767 - 1.83 0.322 - 287 1 2 0 0.0022 8 0 0 0 2.00E+09 2.58E+09 - - - 3.2412 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.13034.13034.2 0.0487 14-Aug K.VVLVLAGR.Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 825.5436 0.77 47192 13034 2 825.54545 413.7791 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2910 - 2.12E+06 - - - 2.2131 - 1.449 0.379 - 323.2 1 2 0 0.0018 8 0 0 0 2.00E+09 2.59E+09 - - - 2.9583 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.13039.13039.2 0.149 12-Jul R.FASFIER.V sp|P07196|NFL_HUMAN 1 868.4443 2.03 47196 13039 2 868.444638 435.2294 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2910.6 - 1.17E+06 - - - 0.3857 - 1.582 0.177 - 143.5 1 2 0 0.0003 7 0 0 0 1.14E+08 5.61E+07 - - - 1.8016 0.9813 230117_WJC_METTL3_WT_vs_EV_F06.13050.13050.2 0.0196 12-Aug R.FASFIER[166.11].V sp|P07196|NFL_HUMAN 1 878.4526 1.97 47202 13050 2 878.457514 440.2336 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2912 - 1.51E+06 - - - 5.6247 - 1.587 0.179 - 221 1 2 0 0.0049 7 0 0 0 1.11E+08 5.60E+07 - - - 1.8249 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.13051.13051.2 0.275 18-Aug R.LGLMPPPEPK.V sp|O43395|PRPF3_HUMAN 1 1077.5893 5.58 47203 13051 2 1077.591231 539.8019 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6 2912.1 - 135039 - - - 1.8356 - 1.695 0.188 - 168.6 1 2 0 0.002 10 0 0 0 7.65E+06 1.37E+06 - - - 1.9019 0.9965 230117_WJC_METTL3_WT_vs_EV_F06.13058.13058.2 1.08 14-Jun K.LTPVLLAK.Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 853.5637 1.74 47205 13058 2 853.564866 427.7891 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2913.1 - 9.26E+06 - - - 1.3778 - 0.943 0.322 - 95.4 1 2 0 0.0012 8 0 0 0 3.30E+08 1.90E+08 - - - 1.2419 0.9788 230117_WJC_METTL3_WT_vs_EV_F06.13059.13059.2 1.48 18-Aug R.VNC[160.03]LAPGLIK[136.11].T "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN" 3 1091.6253 0.93 47206 13059 2 1091.626855 546.8199 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 8.19 2913.2 - 922126 - - - 1.4694 - 1.017 0.137 - 56.3 2 2 0 0.0016 10 0 0 0 9.70E+06 1.05E+07 - - - -0.035 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.13068.13068.2 0.0397 12-Jul K.ILMEFNK.M sp|Q9UQE7|SMC3_HUMAN 1 893.4681 1.58 47211 13068 2 893.469618 447.7413 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2914.4 - 402966 - - - 1.727 - 1.368 0.301 - 115.5 1 2 0 0.0015 7 0 0 0 6.55E+07 4.15E+07 - - - 2.2566 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.13082.13082.2 1.34 12-Aug R.LISSLLR.T "sp|Q9BQ52|RNZ2_HUMAN,sp|Q8NCN5|PDPR_HUMAN,sp|Q96P20|NLRP3_HUMAN,sp|Q96MN2|NALP4_HUMAN,sp|Q8NGV5|O13D1_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|A0A7I2PMC6|A0A7I2PMC6_HUMAN,tr|E7ES68|E7ES68_HUMAN,tr|A0A2R8YEG7|A0A2R8YEG7_HUMAN,tr|A8MT40|A8MT40_HUMAN,tr|A0A7I2PJH0|A0A7I2PJH0_HUMAN,tr|H3BQG3|H3BQG3_HUMAN,tr|A0A7I2PRX0|A0A7I2PRX0_HUMAN,tr|A0A7I2YME5|A0A7I2YME5_HUMAN,tr|A0A286YF94|A0A286YF94_HUMAN,tr|A0A7I2UNQ2|A0A7I2UNQ2_HUMAN,tr|A0A7I2R3P8|A0A7I2R3P8_HUMAN" 17 800.512 1.56 47218 13082 2 800.513112 401.2633 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 9.75 2916.2 - 942913 - - - 1.4029 - 1.547 0.117 - 171.5 1 2 0 0.0011 7 0 0 0 3.12E+07 2.00E+07 - - - 1.2873 0.999 230117_WJC_METTL3_WT_vs_EV_F06.13084.13084.2 0.272 14-Sep K.IADFGLAR.L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 861.4709 2.89 47220 13084 2 861.47203 431.7427 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2916.4 - 2.75E+06 - - - 1.3674 - 1.741 0.241 - 179.4 2 2 0 0.0012 8 0 0 0 1.25E+08 4.33E+07 - - - 2.3584 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.13090.13090.2 0.667 14-Aug K.LLAEVTLK.T "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 4 885.5535 2.54 47223 13090 2 885.55452 443.784 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 6 2917.1 - 1.27E+06 - - - 1.1304 - 1.326 0.218 - 148.4 1 2 0 0.001 8 0 0 0 1.37E+08 5.37E+07 - - - 1.5018 0.99 230117_WJC_METTL3_WT_vs_EV_F06.13094.13094.2 1.65 14-May R.LFAAELGR.E "sp|O00255|MEN1_HUMAN,tr|A0A5F9ZHS3|A0A5F9ZHS3_HUMAN,tr|E7EN32|E7EN32_HUMAN,tr|Q9GZQ5|Q9GZQ5_HUMAN,tr|E7ENS2|E7ENS2_HUMAN" 5 875.4865 1.39 47225 13094 2 875.488529 438.7505 Menin OS=Homo sapiens OX=9606 GN=MEN1 PE=1 SV=4 6 2917.5 - 1.12E+06 - - - 2.3153 - 1.332 0.18 - 45.7 22 2 0 0.002 8 0 0 0 5.12E+07 3.68E+07 - - - 0.6348 0.9946 230117_WJC_METTL3_WT_vs_EV_F06.13097.13097.2 1.77 12-Jul R.VNLLAVR.D "sp|Q9H4H8|FA83D_HUMAN,tr|A0A087WXK8|A0A087WXK8_HUMAN" 2 783.4967 2.08 47227 13097 2 783.497675 392.7556 Protein FAM83D OS=Homo sapiens OX=9606 GN=FAM83D PE=1 SV=3 9.72 2917.9 - 703772 - - - 1.2789 - 1.601 0.052 - 133.8 1 2 0 0.001 7 0 0 0 1.99E+07 9.60E+06 - - - 0.916 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.13098.13098.2 0.751 12-Jul K.ILMEFNK[136.11].M sp|Q9UQE7|SMC3_HUMAN 1 901.4823 1.56 47228 13098 2 901.484173 451.7484 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2917.9 - 846810 - - - 2.1054 - 1.288 0.183 - 114.2 1 2 0 0.0019 7 0 0 0 6.87E+07 4.39E+07 - - - 1.194 0.988 230117_WJC_METTL3_WT_vs_EV_F06.13121.13121.2 2.77 14-Aug R.NVVYPLYR.L "sp|Q16540|RM23_HUMAN,tr|A8MYK1|A8MYK1_HUMAN,tr|A8MVT4|A8MVT4_HUMAN,tr|A6NJD9|A6NJD9_HUMAN" 4 1022.5549 999 47238 13121 2 1022.557669 512.2847 "39S ribosomal protein L23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL23 PE=1 SV=1" 8.59 2921 - 584495 - - - 2.6923 - 1.233 0.131 - 222.6 1 2 0 0.0028 8 0 0 0 3.49E+07 0.00E+00 - - - 0.6394 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.13128.13128.2 0.00184 20-Jul K.YGQISEVVVVK[136.11].D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1227.6954 0.95 47243 13128 2 1227.697367 614.855 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2921.9 - 96567.7 - - - 1.5704 - 1.51 0.355 - 108 1 2 0 0.0019 11 0 0 0 4.89E+06 5.13E+06 - - - 2.7773 0.9861 230117_WJC_METTL3_WT_vs_EV_F06.13131.13131.2 0.374 14-Jun K.LLAEVTLK[136.11].T "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 4 893.5677 2.54 47244 13131 2 893.568897 447.7911 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 6 2922.3 - 1.49E+06 - - - 1.3183 - 0.98 0.171 - 59.8 1 2 0 0.0012 8 0 0 0 1.37E+08 5.38E+07 - - - 0.2427 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.13133.13133.2 1.67 12-Aug R.LALEELR.S sp|Q99496|RING2_HUMAN 1 842.4862 1.03 47246 13133 2 842.486921 422.2504 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.53 2922.5 - 885227 - - - 0.8938 - 1.729 0.09 - 202.3 1 2 0 0.0008 7 0 0 0 2.83E+08 2.75E+08 - - - 1.4404 0.9916 230117_WJC_METTL3_WT_vs_EV_F06.13136.13136.2 1.12 14-Jul K.LALDYGIK[136.11].F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 899.5208 1.47 47247 13136 2 899.523768 450.7677 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 2922.9 - 486178 - - - 3.334 - 1.534 0.118 - 109.7 1 2 0 0.003 8 0 0 0 2.57E+07 1.75E+07 - - - 1.2021 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.13138.13138.2 0.000722 20-Aug K.YGQISEVVVVK[136.11].D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1227.6954 0.95 47249 13138 2 1227.698284 614.855 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2923.1 - 122924 - - - 2.3173 - 1.688 0.306 - 181.8 1 2 0 0.0028 11 0 0 0 4.89E+06 5.13E+06 - - - 2.7165 0.998 230117_WJC_METTL3_WT_vs_EV_F06.13142.13142.2 8.18 14-Aug K.IGDFGLAR.D "sp|P08922|ROS1_HUMAN,sp|P07333|CSF1R_HUMAN,sp|P51617|IRAK1_HUMAN,sp|Q96PY6|NEK1_HUMAN,sp|P51955|NEK2_HUMAN,sp|Q6P3R8|NEK5_HUMAN,sp|Q16659|MK06_HUMAN,sp|P31152|MK04_HUMAN,tr|E9PIX7|E9PIX7_HUMAN,tr|H7C2I6|H7C2I6_HUMAN,tr|K7EN18|K7EN18_HUMAN,tr|A0A494C168|A0A494C168_HUMAN,tr|F6U4U2|F6U4U2_HUMAN,tr|H7C224|H7C224_HUMAN,tr|K7ELV1|K7ELV1_HUMAN,tr|Q5H8Y1|Q5H8Y1_HUMAN,tr|A0A3B3ITQ6|A0A3B3ITQ6_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 18 847.4552 2.25 47251 13142 2 847.455461 424.7349 Proto-oncogene tyrosine-protein kinase ROS OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3 5.84 2923.6 - 2.62E+06 - - - 0.3056 - 1.894 0.13 - 194.1 1 2 0 0.0003 8 0 0 0 8.41E+07 3.74E+07 - - - 1.9274 0.9923 230117_WJC_METTL3_WT_vs_EV_F06.13144.13144.2 0.561 14-Jun R.IFNTFGPR[166.11].M "sp|Q8NBZ7|UXS1_HUMAN,tr|C9JCB7|C9JCB7_HUMAN,tr|C9JFU6|C9JFU6_HUMAN,tr|C9JE50|C9JE50_HUMAN" 4 960.5057 0.81 47253 13144 2 960.504953 481.2601 UDP-glucuronic acid decarboxylase 1 OS=Homo sapiens OX=9606 GN=UXS1 PE=1 SV=1 9.75 2923.8 - 629034 - - - -0.7475 - 1.284 0.202 - 77.1 1 2 0 -0.0007 8 0 0 0 3.71E+07 4.57E+07 - - - 1.2867 0.998 230117_WJC_METTL3_WT_vs_EV_F06.13148.13148.2 3.7 14-Aug K.IGDFGLAR[166.11].D "sp|P08922|ROS1_HUMAN,sp|P07333|CSF1R_HUMAN,sp|P51617|IRAK1_HUMAN,sp|Q96PY6|NEK1_HUMAN,sp|P51955|NEK2_HUMAN,sp|Q6P3R8|NEK5_HUMAN,sp|Q16659|MK06_HUMAN,sp|P31152|MK04_HUMAN,tr|E9PIX7|E9PIX7_HUMAN,tr|H7C2I6|H7C2I6_HUMAN,tr|K7EN18|K7EN18_HUMAN,tr|A0A494C168|A0A494C168_HUMAN,tr|F6U4U2|F6U4U2_HUMAN,tr|H7C224|H7C224_HUMAN,tr|K7ELV1|K7ELV1_HUMAN,tr|Q5H8Y1|Q5H8Y1_HUMAN,tr|A0A3B3ITQ6|A0A3B3ITQ6_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 18 857.4635 2.21 47254 13148 2 857.464227 429.739 Proto-oncogene tyrosine-protein kinase ROS OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3 5.84 2924.4 - 983852 - - - 0.8805 - 1.751 0.142 - 172.1 1 2 0 0.0008 8 0 0 0 8.41E+07 3.80E+07 - - - 1.7791 0.9944 230117_WJC_METTL3_WT_vs_EV_F06.13149.13149.2 3.81 14-Jun K.LLVLDATK.R "sp|O15530|PDPK1_HUMAN,sp|Q6A1A2|PDPK2_HUMAN,tr|E9PER6|E9PER6_HUMAN" 3 871.5379 3.01 47255 13149 2 871.537971 436.7762 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1 5.84 2924.5 - 529212 - - - 0.117 - 1.053 0.262 - 71.6 1 2 0 0.0001 8 0 0 0 1.24E+07 4.11E+06 - - - 1.1319 0.997 230117_WJC_METTL3_WT_vs_EV_F06.13153.13153.2 0.395 14-May K.VLPITVPK.S sp|Q9ULW0|TPX2_HUMAN 1 865.5637 2.04 47256 13153 2 865.565569 433.7891 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.72 2925.1 - 356158 - - - 2.1708 - 1.086 0.302 - 50.4 1 2 0 0.0019 8 0 0 0 5.54E+07 2.72E+07 - - - 1.5198 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.13162.13162.2 0.0145 16-Jul R.EQVNDLFSR.K "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1106.5356 0.68 47261 13162 2 1106.537504 554.2751 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 2926.2 - 103216 - - - 1.6872 - 1.516 0.244 - 133.3 1 2 0 0.0019 9 0 0 0 5.08E+06 7.44E+06 - - - 2.0463 0.9389 230117_WJC_METTL3_WT_vs_EV_F06.13172.13172.2 0.0141 14-Aug E.ILNPLVSK.A "sp|Q6NUP7|PP4R4_HUMAN,sp|Q9BSC4|NOL10_HUMAN,tr|G3V431|G3V431_HUMAN" 3 882.5539 1.05 47267 13172 2 882.554283 442.2842 Serine\threonine-protein phosphatase 4 regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PPP4R4 PE=1 SV=1 8.75 2927.5 - 1.68E+06 - - - 0.4861 - 1.402 0.37 - 141.5 1 1 0 0.0004 8 0 0 0 8.84E+07 8.45E+07 - - - 2.7928 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.13180.13180.2 0.301 16-Aug R.ILVLNGGYR.G "sp|O60870|KIN17_HUMAN,tr|S4R357|S4R357_HUMAN" 2 1003.5815 1.71 47272 13180 2 1003.582946 502.798 DNA\RNA-binding protein KIN17 OS=Homo sapiens OX=9606 GN=KIN PE=1 SV=2 8.75 2928.5 - 720868 - - - 1.4757 - 1.669 0.318 - 205.6 1 2 0 0.0015 9 0 0 0 2.11E+07 1.24E+07 - - - 2.8712 0.9515 230117_WJC_METTL3_WT_vs_EV_F06.13183.13183.2 0.842 12-Jun K.AVFLVPK[136.11].W sp|Q9H2M9|RBGPR_HUMAN 1 780.4989 2.36 47275 13183 2 780.499979 391.2567 Rab3 GTPase-activating protein non-catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP2 PE=1 SV=1 8.8 2928.7 - 805801 - - - 1.3684 - 1.013 0.075 - 96.7 3 2 0 0.0011 7 0 0 0 5.03E+07 2.13E+07 - - - -0.5776 0.999 230117_WJC_METTL3_WT_vs_EV_F06.13188.13188.2 0.000726 14-Sep K.VVNPLFEK.R "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 944.5331 0.78 47278 13188 2 944.532044 473.2738 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.97 2929.4 - 781995 - - - -1.1371 - 1.737 0.417 - 251.2 1 2 0 -0.0011 8 0 0 0 8.82E+07 1.13E+08 - - - 3.7859 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.13189.13189.2 0.241 14-Nov K.INELLLAK.E "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 912.5644 1.99 47279 13189 2 912.565686 457.2895 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 6 2929.5 - 1.14E+06 - - - 1.3895 - 1.88 0.142 - 290.7 1 2 0 0.0013 8 0 0 0 4.08E+07 2.05E+07 - - - 1.9933 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.13190.13190.2 0.128 14-Sep K.INELLLAK[136.11].E "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 920.5786 2.57 47280 13190 2 920.581114 461.2966 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 6 2929.6 - 1.06E+06 - - - 2.7113 - 1.497 0.253 - 160.8 2 2 0 0.0025 8 0 0 0 5.36E+07 2.08E+07 - - - 1.9912 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.13196.13196.2 0.554 14-Aug K.VVNPLFEK[136.11].R "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 952.5473 0.79 47284 13196 2 952.54788 477.2809 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.97 2930.2 - 1.74E+06 - - - 0.59 - 1.46 0.331 - 190.5 1 2 0 0.0006 8 0 0 0 8.93E+07 1.13E+08 - - - 2.6269 0.999 230117_WJC_METTL3_WT_vs_EV_F06.13205.13205.2 0.0137 14-Aug K.VLTISTLR.L "sp|Q12830|BPTF_HUMAN,tr|F5GXF5|F5GXF5_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN,tr|A0A0A0MR81|A0A0A0MR81_HUMAN" 6 901.5597 0.55 47289 13205 2 901.560937 451.7871 Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3 9.72 2931.4 - 562246 - - - 1.4087 - 1.464 0.301 - 164.5 1 2 0 0.0013 8 0 0 0 1.30E+07 2.34E+07 - - - 2.4134 0.9119 230117_WJC_METTL3_WT_vs_EV_F06.13217.13217.2 0.489 14-Sep S.LAELTGIK[136.11].W "sp|Q71F56|MD13L_HUMAN,tr|A0A3B3IS36|A0A3B3IS36_HUMAN,tr|A0A3B3IRX3|A0A3B3IRX3_HUMAN" 3 851.5208 0.56 47297 13217 2 851.52209 426.7677 Mediator of RNA polymerase II transcription subunit 13-like OS=Homo sapiens OX=9606 GN=MED13L PE=1 SV=1 6 2932.9 - 3.93E+06 - - - 1.5513 - 1.722 0.205 - 259.7 1 1 0 0.0013 8 0 0 0 9.26E+07 1.65E+08 - - - 2.1938 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.13226.13226.2 0.16 12-Jul R.NLPMHLR.R "sp|Q9P2E3|ZNFX1_HUMAN,tr|Q5JXR6|Q5JXR6_HUMAN,tr|Q5JXR7|Q5JXR7_HUMAN,tr|Q5JXR5|Q5JXR5_HUMAN" 4 879.4749 135.77 47303 13226 2 879.475887 440.7447 NFX1-type zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=ZNFX1 PE=2 SV=2 9.76 2934 - 2.72E+06 - - - 1.1314 - 1.332 0.256 - 190 1 2 0 0.001 7 0 0 0 1.80E+08 1.32E+06 - - - 1.8399 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.13235.13235.2 0.531 16-Aug K.LLSGNLALR[166.11].S sp|Q53S58|TM177_HUMAN 1 965.5897 1.15 47310 13235 2 965.589645 483.8021 Transmembrane protein 177 OS=Homo sapiens OX=9606 GN=TMEM177 PE=1 SV=1 9.75 2935.1 - 194667 - - - -0.0932 - 1.623 0.179 - 142.7 1 2 0 -0.0001 9 0 0 0 7.09E+06 6.16E+06 - - - 1.7641 0.8497 230117_WJC_METTL3_WT_vs_EV_F06.13239.13239.2 0.276 14-Aug S.LAELTGIK.W "sp|Q71F56|MD13L_HUMAN,tr|A0A3B3IS36|A0A3B3IS36_HUMAN,tr|A0A3B3IRX3|A0A3B3IRX3_HUMAN" 3 843.5066 0.56 47312 13239 2 843.509162 422.7606 Mediator of RNA polymerase II transcription subunit 13-like OS=Homo sapiens OX=9606 GN=MED13L PE=1 SV=1 6 2935.7 - 4.52E+06 - - - 3.0741 - 1.609 0.238 - 190.4 1 1 0 0.0026 8 0 0 0 9.13E+07 1.62E+08 - - - 2.2325 0.9728 230117_WJC_METTL3_WT_vs_EV_F06.13240.13240.2 8.92 14-May R.LFVGSIPK.S "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 859.5167 0.9 47313 13240 2 859.517937 430.7656 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.75 2935.7 - 2.38E+06 - - - 1.3926 - 1.102 0.092 - 87.1 3 2 0 0.0012 8 0 0 0 1.47E+09 1.63E+09 - - - -0.2001 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.13247.13247.2 0.00492 12-Jul K.YGVDLIR.Y sp|Q6UXN9|WDR82_HUMAN 1 834.46 2.66 47318 13247 2 834.462157 418.2373 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 5.84 2936.6 - 790868 - - - 2.6412 - 1.399 0.192 - 179.4 1 2 0 0.0022 7 0 0 0 2.27E+08 8.56E+07 - - - 1.5223 0.9743 230117_WJC_METTL3_WT_vs_EV_F06.13248.13248.2 1.64 12-May K.FIPLYSK[136.11].V "sp|Q14694|UBP10_HUMAN,tr|J3KT19|J3KT19_HUMAN,tr|H3BVF1|H3BVF1_HUMAN" 3 874.5044 1.21 47319 13248 2 874.505712 438.2595 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.59 2936.7 - 576221 - - - 1.5106 - 1.01 0.104 - 67.9 1 2 0 0.0013 7 0 0 0 1.14E+08 9.44E+07 - - - -0.1597 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.13254.13254.2 0.0785 14-Jul R.IFTNLYGR.H "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 4 982.5236 1.12 47323 13254 2 982.527343 492.2691 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.75 2937.5 - 508845 - - - 3.7933 - 1.542 0.306 - 145.9 1 2 0 0.0037 8 0 0 0 5.98E+07 5.33E+07 - - - 2.6061 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.13255.13255.2 5.82E-05 14-Aug -.MFAPAVMR.A sp|Q9P0S2|COX16_HUMAN 1 921.4565 1.55 47324 13255 2 921.456308 461.7355 "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COX16 PE=1 SV=1" 9.5 2937.6 - 683552 - - - -0.1693 - 1.587 0.229 - 209.6 1 2 0 -0.0002 8 0 0 0 3.81E+07 2.47E+07 - - - 2.1252 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.13257.13257.2 5.89E-05 14-Sep -.MFAPAVMR[166.11].A sp|Q9P0S2|COX16_HUMAN 1 931.4647 1.54 47326 13257 2 931.464236 466.7396 "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COX16 PE=1 SV=1" 9.5 2937.8 - 470325 - - - -0.5346 - 1.875 0.238 - 311.6 1 2 0 -0.0005 8 0 0 0 3.80E+07 2.47E+07 - - - 2.6946 0.9932 230117_WJC_METTL3_WT_vs_EV_F06.13262.13262.2 0.348 12-Jun R.GFLAEMK.R "sp|A6ZKI3|RTL8C_HUMAN,sp|Q9BWD3|RTL8A_HUMAN,sp|Q17RB0|RTL8B_HUMAN" 3 794.3997 0.81 47329 13262 2 794.400196 398.2071 Retrotransposon Gag-like protein 8C OS=Homo sapiens OX=9606 GN=RTL8C PE=1 SV=1 6 2938.4 - 628581 - - - 0.6735 - 1.085 0.206 - 84.3 1 2 0 0.0005 7 0 0 0 2.76E+07 3.40E+07 - - - 0.8208 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.13275.13275.2 0.1 22-Aug R.LLLGPAGGGVPK.L sp|Q96SL8|FIZ1_HUMAN 1 1077.6546 1.27 47334 13275 2 1077.656204 539.8346 Flt3-interacting zinc finger protein 1 OS=Homo sapiens OX=9606 GN=FIZ1 PE=1 SV=2 8.75 2940.2 - 193891 - - - 1.4606 - 1.464 0.221 - 114.4 1 2 0 0.0016 12 0 0 0 9.59E+06 7.56E+06 - - - 1.6757 0.99 230117_WJC_METTL3_WT_vs_EV_F06.13277.13277.2 0.214 12-Oct K.MLGGVFK[136.11].L "sp|Q96MU7|YTDC1_HUMAN,tr|J3QR07|J3QR07_HUMAN" 2 758.424 0.001 47336 13277 2 758.425691 380.2193 YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3 8.5 2940.5 - 760610 - - - 2.1874 - 1.286 0.102 - 277.5 1 2 0 0.0017 7 0 0 0 0.00E+00 3.09E+07 - - - 0.5909 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.13282.13282.2 0.0139 14-Sep R.LLAAFEER.E "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 947.5076 1.34 47339 13282 2 947.509061 474.7611 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.53 2941.1 - 1.45E+06 - - - 1.5082 - 1.8 0.279 - 244.9 1 2 0 0.0014 8 0 0 0 1.68E+08 1.26E+08 - - - 2.874 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.13283.13283.2 0.0802 12-Jul K.YGVDLIR[166.11].Y sp|Q6UXN9|WDR82_HUMAN 1 844.4682 2.87 47340 13283 2 844.469824 423.2414 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 5.84 2941.1 - 1.40E+06 - - - 1.8959 - 1.56 0.319 - 198.7 1 2 0 0.0016 7 0 0 0 2.03E+08 7.08E+07 - - - 2.8056 0.9941 230117_WJC_METTL3_WT_vs_EV_F06.13286.13286.2 0.731 12-Jul K.SVIISIK[136.11].G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 766.5044 1.17 47341 13286 2 766.505597 384.2595 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2941.5 - 933780 - - - 1.5734 - 1.152 0.185 - 198.3 1 2 0 0.0012 7 0 0 0 2.05E+08 1.75E+08 - - - 0.8554 0.9954 230117_WJC_METTL3_WT_vs_EV_F06.13288.13288.2 0.547 12-Aug K.SVIISIK.G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 758.4902 1.17 47342 13288 2 758.491389 380.2524 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2941.7 - 1.07E+06 - - - 1.5795 - 1.242 0.179 - 251.7 1 2 0 0.0012 7 0 0 0 2.05E+08 1.75E+08 - - - 1.0494 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.13290.13290.2 0.0136 14-Aug R.LLAAFEER[166.11].E "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 957.5159 1.32 47343 13290 2 957.516976 479.7652 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.53 2941.9 - 2.09E+06 - - - 1.1217 - 1.611 0.351 - 223.6 1 2 0 0.0011 8 0 0 0 1.68E+08 1.27E+08 - - - 3.0713 0.9934 230117_WJC_METTL3_WT_vs_EV_F06.13298.13298.2 0.261 16-Jun R.EMGVIAAMR.D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 976.4834 2.22 47347 13298 2 976.485708 489.249 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 6.1 2942.9 - 230780 - - - 2.3564 - 1.193 0.19 - 77.3 1 2 0 0.0023 9 0 0 0 1.71E+07 7.67E+06 - - - 0.9542 0.9895 230117_WJC_METTL3_WT_vs_EV_F06.13311.13311.2 0.447 14-Jul K.NLILAGVK.G "sp|Q9UBE0|SAE1_HUMAN,tr|B3KNJ4|B3KNJ4_HUMAN,tr|M0QZS6|M0QZS6_HUMAN,tr|A0A590UKC5|A0A590UKC5_HUMAN,tr|M0QX65|M0QX65_HUMAN,tr|A0A590UKA0|A0A590UKA0_HUMAN,tr|A0A590UK93|A0A590UK93_HUMAN" 7 826.5276 2.86 47352 13311 2 826.52738 414.2711 SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1 PE=1 SV=1 8.75 2944.8 - 1.00E+06 - - - -0.3134 - 1.452 0.091 - 157 1 2 0 -0.0003 8 0 0 0 5.44E+07 1.90E+07 - - - 0.8378 0.997 230117_WJC_METTL3_WT_vs_EV_F06.13328.13328.2 0.717 12-Jul K.IVVLLQR.L "sp|Q06323|PSME1_HUMAN,tr|H0YLU2|H0YLU2_HUMAN" 2 839.5593 1.38 47358 13328 2 839.558016 420.7869 Proteasome activator complex subunit 1 OS=Homo sapiens OX=9606 GN=PSME1 PE=1 SV=1 9.75 2947.2 - 965366 - - - -1.4972 - 1.609 0.283 - 139.2 1 2 0 -0.0013 7 0 0 0 3.25E+07 2.36E+07 - - - 2.6378 1 230117_WJC_METTL3_WT_vs_EV_F06.13329.13329.2 1.09E-09 13/24 R.TTPSYVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1486.694 16.19 47359 13329 2 1486.698865 744.3543 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2947.3 - 753767 - - - 3.2798 - 2.667 0.643 - 656 1 2 0 0.0049 13 0 0 0 7.87E+07 4.86E+06 - - - 6.3063 0.999 230117_WJC_METTL3_WT_vs_EV_F06.13332.13332.2 0.0265 18-Sep R.AFGSLGPGLR.L "sp|Q96JG8|MAGD4_HUMAN,tr|D6RBW3|D6RBW3_HUMAN,tr|A0A804HHZ9|A0A804HHZ9_HUMAN" 3 973.5345 8.16 47360 13332 2 973.53494 487.7745 Melanoma-associated antigen D4 OS=Homo sapiens OX=9606 GN=MAGED4 PE=1 SV=3 9.79 2947.7 - 593310 - - - 0.4366 - 1.534 0.312 - 203 1 2 0 0.0004 10 0 0 0 2.23E+07 2.73E+06 - - - 2.5396 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.13333.13333.2 0.00185 16-Sep K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 300.84 47361 13333 2 1059.557762 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2947.8 - 638850 - - - 1.6271 - 1.639 0.393 - 250.8 1 2 0 0.0017 9 0 0 0 2.54E+07 8.45E+04 - - - 3.3726 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.13337.13337.2 0.697 14-Aug K.LVALNLDR.L "sp|Q9Y3D3|RT16_HUMAN,tr|A6ND22|A6ND22_HUMAN" 2 912.5393 1.16 47363 13337 2 912.538681 457.2769 "28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1" 5.84 2948.4 - 1.02E+06 - - - -0.6411 - 1.666 0.185 - 171.9 1 2 0 -0.0006 8 0 0 0 8.26E+07 7.13E+07 - - - 1.9466 0.9954 230117_WJC_METTL3_WT_vs_EV_F06.13343.13343.2 5.47 12-Aug K.LLDIVAR[166.11].S sp|Q12931|TRAP1_HUMAN 1 808.5046 2.09 47367 13343 2 808.504562 405.2596 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.84 2949.1 - 2.63E+06 - - - -0.0581 - 1.76 0.072 - 215 1 2 0 0 7 0 0 0 3.01E+08 1.44E+08 - - - 1.364 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.13347.13347.2 0.0134 12-Aug K.YVIYIER.V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 954.5175 0.8 47369 13347 2 954.517774 478.266 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 6 2949.5 - 2.02E+06 - - - 0.3206 - 1.421 0.303 - 293 1 2 0 0.0003 7 0 0 0 9.59E+08 1.20E+09 - - - 2.3922 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.13348.13348.2 0.0601 14-Sep R.ILEVLPGR.R sp|Q9UI43|MRM2_HUMAN 1 895.5491 2.82 47370 13348 2 895.551728 448.7818 "rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1" 6 2949.6 - 477195 - - - 2.9323 - 1.71 0.292 - 222.3 1 2 0 0.0026 8 0 0 0 6.33E+07 2.25E+07 - - - 2.8149 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.13352.13352.2 0.0378 18-Nov R.LLAEPVPGIK[136.11].A "sp|P61088|UBE2N_HUMAN,sp|Q5JXB2|UE2NL_HUMAN,tr|F8VZ29|F8VZ29_HUMAN,tr|F8VSD4|F8VSD4_HUMAN,tr|F8VV71|F8VV71_HUMAN" 5 1043.647 1.65 47372 13352 2 1043.646975 522.8308 Ubiquitin-conjugating enzyme E2 N OS=Homo sapiens OX=9606 GN=UBE2N PE=1 SV=1 6 2950.2 - 1.31E+06 - - - -0.0546 - 1.824 0.252 - 342 1 2 0 -0.0001 10 0 0 0 1.24E+08 7.49E+07 - - - 2.5799 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.13353.13353.2 0.00282 12-Aug R.VVFQEFR[166.11].Q sp|P35579|MYH9_HUMAN 1 933.4948 0.91 47373 13353 2 933.494017 467.7547 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2950.3 - 1.10E+06 - - - -0.8088 - 1.49 0.395 - 272 1 2 0 -0.0008 7 0 0 0 2.43E+08 2.68E+08 - - - 3.2218 0.9969 230117_WJC_METTL3_WT_vs_EV_F06.13354.13354.2 0.811 12-Jun K.ELVVLPR.E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 824.512 0.42 47374 13354 2 824.513637 413.2633 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2950.4 - 597133 - - - 1.9988 - 1.407 0.177 - 171.5 1 2 0 0.0016 7 0 0 0 1.51E+08 3.55E+08 - - - 1.4297 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.13358.13358.2 3.26E-06 24-Sep R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 16.15 47376 13358 2 1496.703236 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2950.9 - 263513 - - - 0.6528 - 2.119 0.318 - 257.8 1 2 0 0.001 13 0 0 0 7.85E+07 4.86E+06 - - - 3.3168 0.992 230117_WJC_METTL3_WT_vs_EV_F06.13362.13362.2 9.74 12-Jul K.LLDIVAR.S sp|Q12931|TRAP1_HUMAN 1 798.4963 2.36 47378 13362 2 798.49652 400.2554 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.84 2951.4 - 8.28E+06 - - - 0.2267 - 1.645 0.028 - 166.6 1 2 0 0.0002 7 0 0 0 2.91E+08 1.23E+08 - - - 0.8249 0.9849 230117_WJC_METTL3_WT_vs_EV_F06.13374.13374.2 0.298 18-Jul R.VAQLEQVYIR.G sp|P62318|SMD3_HUMAN 1 1217.6768 1.63 47384 13374 2 1217.678483 609.8457 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.97 2952.8 - 206174 - - - 1.3641 - 1.315 0.052 - 119.8 1 2 0 0.0017 10 0 0 0 4.40E+06 2.69E+06 - - - 0.1889 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.13386.13386.2 0.0494 14-Sep R.LLSTYLER[166.11].Y "sp|Q12769|NU160_HUMAN,tr|G3V198|G3V198_HUMAN" 2 1003.5578 1.32 47389 13386 2 1003.560815 502.7862 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 6 2954.3 - 1.26E+06 - - - 3.0382 - 1.72 0.298 - 246.6 1 2 0 0.003 8 0 0 0 5.76E+07 4.36E+07 - - - 2.8767 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.13389.13389.2 0.0143 14-Sep R.LLSTYLER.Y "sp|Q12769|NU160_HUMAN,tr|G3V198|G3V198_HUMAN" 2 993.5495 1.32 47391 13389 2 993.551422 497.782 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 6 2954.6 - 1.12E+06 - - - 1.9385 - 1.972 0.318 - 232.1 1 2 0 0.0019 8 0 0 0 5.76E+07 4.36E+07 - - - 3.4371 0.9913 230117_WJC_METTL3_WT_vs_EV_F06.13394.13394.2 0.3 14-May R.LFVGSIPK[136.11].S "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 867.5309 0.91 47392 13394 2 867.531732 434.7727 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.75 2955.4 - 4.25E+06 - - - 0.9129 - 1.128 0.219 - 50.9 9 2 0 0.0008 8 0 0 0 1.47E+09 1.62E+09 - - - 0.5953 0.9871 230117_WJC_METTL3_WT_vs_EV_F06.13399.13399.2 0.335 12-May K.ELVVLPR[166.11].E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 834.5203 0.5 47395 13399 2 834.522466 418.2674 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2956 - 5.73E+06 - - - 2.6446 - 1.169 0.14 - 102.5 1 2 0 0.0022 7 0 0 0 1.80E+08 3.60E+08 - - - 0.5691 0.9917 230117_WJC_METTL3_WT_vs_EV_F06.13401.13401.2 0.234 12-Jun R.YLLAMER.H "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 894.4633 2.83 47396 13401 2 894.464209 448.2389 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 2956.2 - 843036 - - - 0.9894 - 1.156 0.152 - 102.1 1 2 0 0.0009 7 0 0 0 3.58E+07 1.26E+07 - - - 0.6227 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.13411.13411.2 0.0146 12-Jul R.VVFQEFR.Q sp|P35579|MYH9_HUMAN 1 923.4865 0.91 47400 13411 2 923.48797 462.7505 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2957.5 - 6.25E+06 - - - 1.5896 - 1.419 0.366 - 201.4 1 2 0 0.0015 7 0 0 0 2.43E+08 2.68E+08 - - - 2.8527 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.13413.13413.2 0.0214 12-Jul R.VVFQEFR.Q sp|P35579|MYH9_HUMAN 1 923.4865 0.91 47401 13413 2 923.488476 462.7505 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2957.7 - 5.56E+06 - - - 2.1376 - 1.469 0.389 - 230.2 1 2 0 0.002 7 0 0 0 2.43E+08 2.68E+08 - - - 3.1321 0.9873 230117_WJC_METTL3_WT_vs_EV_F06.13419.13419.2 3.5 12-May K.IFTFAEK[136.11].Y "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 4 862.468 0.67 47404 13419 2 862.469657 432.2413 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 6 2958.5 - 1.74E+06 - - - 1.9154 - 1.199 0.101 - 50.7 1 2 0 0.0017 7 0 0 0 4.24E+07 6.28E+07 - - - 0.3615 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.13420.13420.2 0.336 16-Sep R.ILVGTNLVR.L sp|Q96QK1|VPS35_HUMAN 1 983.6128 1.94 47405 13420 2 983.614666 492.8137 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 9.75 2958.6 - 1.74E+06 - - - 1.9327 - 1.54 0.17 - 168.5 1 2 0 0.0019 9 0 0 0 6.98E+07 3.59E+07 - - - 1.5452 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.13421.13421.2 0.334 12-Jul R.EALGLLR[166.11].A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 780.4733 1.09 47406 13421 2 780.475002 391.2439 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2958.6 - 2.51E+06 - - - 2.1705 - 1.498 0.164 - 176.1 1 2 0 0.0017 7 0 0 0 2.00E+08 1.84E+08 - - - 1.5323 0.9969 230117_WJC_METTL3_WT_vs_EV_F06.13423.13423.2 0.928 14-Jul K.LLIIGPQK.T "sp|P52848|NDST1_HUMAN,tr|E7EVJ3|E7EVJ3_HUMAN" 2 880.5746 0.89 47408 13423 2 880.575907 441.2946 Bifunctional heparan sulfate N-deacetylase\N-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=NDST1 PE=1 SV=1 8.75 2958.8 - 500292 - - - 1.4967 - 1.406 0.173 - 141.2 1 2 0 0.0013 8 0 0 0 1.78E+07 2.00E+07 - - - 1.346 0.9518 230117_WJC_METTL3_WT_vs_EV_F06.13427.13427.2 1.52 12-May R.FPPYYMR.R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 972.4528 0.97 47410 13427 2 972.45495 487.2337 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 2959.4 - 209529 - - - 2.2531 - 0.912 0.109 - 65 1 2 0 0.0022 7 0 0 0 1.27E+07 1.31E+07 - - - -0.4465 0.9962 230117_WJC_METTL3_WT_vs_EV_F06.13428.13428.2 0.391 12-Jul R.EALGLLR.A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 770.465 1.09 47411 13428 2 770.467122 386.2398 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2959.4 - 2.60E+06 - - - 2.7049 - 1.488 0.167 - 215.5 1 2 0 0.0021 7 0 0 0 2.01E+08 1.85E+08 - - - 1.5331 0.998 230117_WJC_METTL3_WT_vs_EV_F06.13432.13432.2 0.00302 14-Jul K.MMMVLGAK.W "sp|Q14839|CHD4_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|F5H6N4|F5H6N4_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 17 879.438 1.25 47413 13432 2 879.440233 440.7263 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.5 2960 - 412145 - - - 2.497 - 1.342 0.281 - 123.2 1 2 0 0.0022 8 0 0 0 1.79E+07 1.43E+07 - - - 2.003 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.13433.13433.2 0.00743 24-Oct K.VIDPATATSVDLR.D sp|P50991|TCPD_HUMAN 1 1356.7249 999 47414 13433 2 1356.728986 679.3697 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 2960.1 - 118370 - - - 3.0153 - 1.933 0.395 - 241.2 1 2 0 0.0041 13 0 0 0 7.77E+06 0.00E+00 - - - 3.6487 0.9633 230117_WJC_METTL3_WT_vs_EV_F06.13434.13434.2 0.0837 12-Oct K.PSVYFIK[136.11].F "sp|Q99865|SPI2A_HUMAN,sp|Q56A73|SPIN4_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 9 860.4887 0.5 47415 13434 2 860.49089 431.2516 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 9.01 2960.1 - 1.82E+06 - - - 2.4974 - 1.916 0.367 - 315.9 1 1 0 0.0021 7 0 0 0 2.43E+08 4.89E+08 - - - 3.8113 0.9636 230117_WJC_METTL3_WT_vs_EV_F06.13438.13438.2 1.09 12-Jun K.LLWTTSR.V "sp|P35222|CTNB1_HUMAN,sp|P14923|PLAK_HUMAN,tr|A0A2R8Y6G0|A0A2R8Y6G0_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 12 875.4865 6.96 47416 13438 2 875.490975 438.7505 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 9.75 2960.8 - 508855 - - - 5.1092 - 1.117 0.215 - 84.9 1 2 0 0.0045 7 0 0 0 5.07E+07 7.29E+06 - - - 0.9782 0.8831 230117_WJC_METTL3_WT_vs_EV_F06.13444.13444.2 0.0195 12-Aug K.PSVYFIK.F "sp|Q99865|SPI2A_HUMAN,sp|Q56A73|SPIN4_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 9 852.4745 0.5 47419 13444 2 852.47697 427.2445 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 9.01 2961.5 - 1.72E+06 - - - 2.8494 - 1.571 0.26 - 167.3 1 1 0 0.0024 7 0 0 0 2.43E+08 4.89E+08 - - - 2.3919 0.9866 230117_WJC_METTL3_WT_vs_EV_F06.13446.13446.2 1.64 12-Aug K.QLLYLEK.Y "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 3 905.5222 0.7 47421 13446 2 905.524767 453.7684 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 6 2961.7 - 954199 - - - 2.8138 - 1.222 0.127 - 205.6 1 2 0 0.0025 7 0 0 0 6.11E+07 8.75E+07 - - - 0.6135 0.9878 230117_WJC_METTL3_WT_vs_EV_F06.13451.13451.2 0.00583 16-Sep K.LLNYAPLEK.- sp|P62875|RPAB5_HUMAN 1 1059.5964 1.21 47424 13451 2 1059.603938 530.8055 "DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1" 6 2962.4 - 348463 - - - 7.0697 - 1.674 0.384 - 227.7 1 2 0 0.0075 9 0 0 0 1.84E+07 1.52E+07 - - - 3.3654 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.13459.13459.2 0.0128 12-Jul R.VVFQEFR.Q sp|P35579|MYH9_HUMAN 1 923.4865 0.91 47429 13459 2 923.489443 462.7505 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2963.4 - 757055 - - - 3.1847 - 1.429 0.339 - 208.1 1 2 0 0.0029 7 0 0 0 2.43E+08 2.68E+08 - - - 2.675 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.13462.13462.2 0.000186 20-Jul K.NFYYAAVPSAR[166.11].N sp|Q10471|GALT2_HUMAN 1 1267.6225 1.18 47432 13462 2 1267.625256 634.8185 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.59 2963.8 - 74163.9 - - - 2.1805 - 1.493 0.415 - 181.7 1 2 0 0.0028 11 0 0 0 1.06E+06 9.02E+05 - - - 3.1895 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.13467.13467.2 0.000174 20-Aug K.NFYYAAVPSAR.N sp|Q10471|GALT2_HUMAN 1 1257.6142 1.18 47435 13467 2 1257.620295 629.8144 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.59 2964.3 - 63780.1 - - - 4.829 - 1.475 0.405 - 130.4 1 2 0 0.0061 11 0 0 0 1.06E+06 9.02E+05 - - - 3.0818 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.13474.13474.2 0.00344 20-Aug K.QAGVFEPTIVK.V "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1187.655 123.62 47439 13474 2 1187.658794 594.8348 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2965.2 - 197038 - - - 3.1743 - 1.57 0.383 - 158.6 1 2 0 0.0038 11 0 0 0 1.87E+07 1.51E+05 - - - 3.0889 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.13491.13491.2 0.162 14-Sep K.IADFGLAR[166.11].L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 871.4791 1.99 47446 13491 2 871.479603 436.7468 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2967.5 - 1.66E+06 - - - 0.5519 - 1.752 0.19 - 238.3 1 2 0 0.0005 8 0 0 0 9.36E+08 4.71E+08 - - - 2.1354 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.13493.13493.2 0.175 16-Sep R.IVDPEIALK.L "sp|P33240|CSTF2_HUMAN,tr|A0A0A0MT56|A0A0A0MT56_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 996.5855 2.57 47448 13493 2 996.587854 499.3001 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.37 2967.6 - 1.68E+06 - - - 2.3139 - 1.669 0.276 - 183.1 1 2 0 0.0023 9 0 0 0 8.29E+08 3.23E+08 - - - 2.5607 0.9934 230117_WJC_METTL3_WT_vs_EV_F06.13514.13514.2 0.592 12-Jul R.FILIQNR.A "sp|P53680|AP2S1_HUMAN,tr|M0R0N4|M0R0N4_HUMAN,tr|X6R390|X6R390_HUMAN,tr|M0QYZ2|M0QYZ2_HUMAN" 4 902.5338 1.09 47460 13514 2 902.534248 452.2742 AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2 9.75 2970.2 - 1.15E+06 - - - 0.5108 - 1.215 0.166 - 168.5 1 2 0 0.0005 7 0 0 0 4.06E+07 3.73E+07 - - - 0.884 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.13520.13520.2 0.121 14-Sep K.LLQLVEDR.G "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 984.5604 0.55 47464 13520 2 984.562799 493.2875 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 2970.9 - 992883 - - - 2.4417 - 1.733 0.204 - 256.7 1 2 0 0.0024 8 0 0 0 1.42E+08 2.56E+08 - - - 2.2053 0.9895 230117_WJC_METTL3_WT_vs_EV_F06.13526.13526.2 0.0534 12-Jul R.YFEPLVK.K "sp|Q7L590|MCM10_HUMAN,tr|Q5T670|Q5T670_HUMAN" 2 894.4851 1.26 47468 13526 2 894.48446 448.2498 Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2 6 2971.6 - 388667 - - - -0.7211 - 1.112 0.224 - 109.2 1 2 0 -0.0006 7 0 0 0 2.76E+07 2.18E+07 - - - 1.0316 1 230117_WJC_METTL3_WT_vs_EV_F06.13541.13541.2 0.000245 16-Oct K.PLYVALAQR[166.11].K "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PIK9|A0A6I8PIK9_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 25 1039.6054 1.12 47476 13541 2 1039.606409 520.81 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.18 2973.2 - 845169 - - - 0.985 - 2.169 0.506 - 433.7 1 1 0 0.001 9 0 0 0 4.10E+08 3.65E+08 - - - 5.018 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.13565.13565.2 0.228 14-Sep K.IADFGLAR.L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 861.4709 1.98 47487 13565 2 861.47078 431.7427 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2976.1 - 2.12E+07 - - - -0.0836 - 1.853 0.29 - 268.3 1 2 0 -0.0001 8 0 0 0 9.31E+08 4.70E+08 - - - 3.0432 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.13575.13575.2 0.0505 18-Nov K.LAELEEALQK.A "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1142.6183 999 47493 13575 2 1142.618729 572.3164 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.25 2977.3 - 205092 - - - 0.372 - 2.34 0.313 - 363.7 1 2 0 0.0004 10 0 0 0 7.25E+06 0.00E+00 - - - 3.7257 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.13581.13581.2 0.00627 12-Sep K.C[160.03]FLTAMR[166.11].E "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN" 3 907.4283 1.69 47494 13581 2 907.429619 454.7215 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 8.25 2978.2 - 438066 - - - 1.3996 - 1.499 0.393 - 243.7 1 2 0 0.0013 7 0 0 0 4.45E+07 2.62E+07 - - - 3.2259 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.13583.13583.2 6.24 14-Aug K.LAVEAVLR.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 869.5335 7.19 47495 13583 2 869.533205 435.774 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 2978.4 - 9.79E+06 - - - -0.2841 - 1.701 0.224 - 235.5 1 2 0 -0.0002 8 0 0 0 5.67E+09 7.88E+08 - - - 2.2975 0.9898 230117_WJC_METTL3_WT_vs_EV_F06.13584.13584.2 4.72 14-Sep R.LAVEALVR[166.11].T "sp|Q92839|HYAS1_HUMAN,tr|M0QXH4|M0QXH4_HUMAN,tr|G3V1S7|G3V1S7_HUMAN,tr|M0R2V0|M0R2V0_HUMAN" 4 879.5417 7.19 47496 13584 2 879.542076 440.7781 Hyaluronan synthase 1 OS=Homo sapiens OX=9606 GN=HAS1 PE=1 SV=2 6 2978.5 - 1.52E+06 - - - 0.4025 - 1.464 0.055 - 325.5 1 2 0 0.0004 8 0 0 0 5.66E+09 7.88E+08 - - - 0.5967 0.9953 230117_WJC_METTL3_WT_vs_EV_F06.13588.13588.2 0.0555 14-Sep R.LLAFAEAR.A "sp|Q8WUY8|NAT14_HUMAN,sp|Q99519|NEUR1_HUMAN,tr|M0R1E3|M0R1E3_HUMAN,tr|E9PIF4|E9PIF4_HUMAN" 4 889.5022 1.95 47498 13588 2 889.500536 445.7584 Probable N-acetyltransferase 14 OS=Homo sapiens OX=9606 GN=NAT14 PE=1 SV=1 6 2979 - 1.34E+06 - - - -1.8167 - 1.791 0.209 - 191.7 1 2 0 -0.0016 8 0 0 0 5.74E+07 2.94E+07 - - - 2.3418 0.9257 230117_WJC_METTL3_WT_vs_EV_F06.13602.13602.2 0.997 14-Sep R.ALVIVMGK[136.11].E "tr|G5E9Q6|G5E9Q6_HUMAN,tr|C9J0J7|C9J0J7_HUMAN" 2 837.5237 3.12 47505 13602 2 837.518825 419.7691 Profilin OS=Homo sapiens OX=9606 GN=PFN2 PE=1 SV=1 8.8 2980.7 - 1.16E+06 - - - -5.8757 - 1.547 0.231 - 214.8 1 2 0 -0.0049 8 0 0 0 1.19E+08 3.82E+07 - - - 2.0615 0.9631 230117_WJC_METTL3_WT_vs_EV_F06.13604.13604.2 0.0848 14-Aug K.LLQPLVPR.Y sp|Q8N8A6|DDX51_HUMAN 1 934.5964 1.06 47507 13604 2 934.59297 468.3055 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2981 - 761494 - - - -3.6561 - 1.268 0.234 - 185.6 1 2 0 -0.0034 8 0 0 0 1.01E+08 9.49E+07 - - - 1.4844 0.9044 230117_WJC_METTL3_WT_vs_EV_F06.13607.13607.2 2.51 12-Jun R.YLDELMK[136.11].L "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 918.4612 1.73 47508 13607 2 918.45975 460.2379 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 2981.4 - 910110 - - - -1.5842 - 1.099 0.113 - 78.2 6 2 0 -0.0015 7 0 0 0 4.69E+07 2.71E+07 - - - -0.1733 0.999 230117_WJC_METTL3_WT_vs_EV_F06.13616.13616.2 0.00661 14-Aug K.ILDVMYSR[166.11].L sp|P78527|PRKDC_HUMAN 1 1005.5193 0.93 47510 13616 2 1005.518588 503.7669 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2982.7 - 661468 - - - -0.6802 - 1.427 0.433 - 127.9 1 2 0 -0.0007 8 0 0 0 6.67E+07 7.14E+07 - - - 3.3113 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.13630.13630.2 0.326 12-Aug K.ILEVDLK.N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 828.4957 0.8 47515 13630 2 828.495343 415.2551 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2984.6 - 3.75E+06 - - - -0.3947 - 1.624 0.153 - 181.8 1 2 0 -0.0003 7 0 0 0 2.67E+08 3.32E+08 - - - 1.7074 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.13645.13645.2 0.0316 16-Sep K.VLEEALLSR[166.11].E "sp|Q92667|AKAP1_HUMAN,tr|I3L0W0|I3L0W0_HUMAN" 2 1038.5949 1.14 47523 13645 2 1038.595339 520.3047 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 4.53 2986.4 - 969808 - - - 0.4419 - 1.93 0.262 - 245.2 1 2 0 0.0005 9 0 0 0 2.59E+08 2.28E+08 - - - 2.8782 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.13650.13650.2 0.385 12-Aug R.YLLLNPK.E "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 859.5167 0.02 47526 13650 2 859.518033 430.7656 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 8.59 2987.1 - 969562 - - - 1.5043 - 1.554 0.16 - 195.6 1 2 0 0.0013 7 0 0 0 8.85E+07 5.11E+09 - - - 1.6192 0.998 230117_WJC_METTL3_WT_vs_EV_F06.13651.13651.2 0.0633 14-Aug R.LPANLLYK.Y sp|Q9NVR2|INT10_HUMAN 1 930.5539 1.39 47527 13651 2 930.555404 466.2842 Integrator complex subunit 10 OS=Homo sapiens OX=9606 GN=INTS10 PE=1 SV=2 8.59 2987.2 - 323082 - - - 1.6657 - 1.384 0.232 - 121.2 1 2 0 0.0016 8 0 0 0 7.84E+06 5.63E+06 - - - 1.7342 0.9962 230117_WJC_METTL3_WT_vs_EV_F06.13655.13655.2 0.0307 18-Sep K.QQLLIGAYAK.A sp|Q99832|TCPH_HUMAN 1 1103.6339 128.52 47529 13655 2 1103.631628 552.8242 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.59 2987.7 - 380645 - - - -2.0541 - 1.582 0.332 - 199.3 1 2 0 -0.0023 10 0 0 0 7.49E+06 5.83E+04 - - - 2.7728 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.13667.13667.2 0.0621 12-Aug K.EAVLLLK[136.11].K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 792.52 0.74 47534 13667 2 792.521129 397.2673 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 2989.4 - 1.97E+06 - - - 1.3728 - 1.543 0.204 - 250.7 1 2 0 0.0011 7 0 0 0 5.97E+08 8.03E+08 - - - 1.9217 0.9549 230117_WJC_METTL3_WT_vs_EV_F06.13669.13669.2 3.91 18-Jun K.SSEQILATLK.G sp|Q9UMS4|PRP19_HUMAN 1 1088.6077 1.18 47536 13669 2 1088.611044 545.3111 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.72 2989.6 - 139506 - - - 3.0351 - 1.26 0.079 - 57.5 8 2 0 0.0033 10 0 0 0 3.10E+06 2.62E+06 - - - -0.1349 0.9938 230117_WJC_METTL3_WT_vs_EV_F06.13674.13674.2 1.7 12-Jul R.LLQIIER[166.11].Y sp|P78527|PRKDC_HUMAN 1 893.5574 1.19 47538 13674 2 893.558378 447.786 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2990.3 - 1.90E+06 - - - 1.1258 - 1.433 0.087 - 174.7 1 2 0 0.001 7 0 0 0 2.47E+08 2.07E+08 - - - 0.8232 0.9969 230117_WJC_METTL3_WT_vs_EV_F06.13680.13680.2 0.774 12-Sep K.EAVLLLK.K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 784.5058 0.74 47542 13680 2 784.506663 393.2602 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 2991 - 2.55E+06 - - - 1.0478 - 1.648 0.099 - 345.7 1 2 0 0.0008 7 0 0 0 5.96E+08 8.03E+08 - - - 1.3548 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.13681.13681.2 0.383 12-Jul K.VLEILGK[136.11].K "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 10 778.5044 2.49 47543 13681 2 778.505383 390.2595 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.97 2991.1 - 536800 - - - 1.2742 - 1.573 0.232 - 113 1 2 0 0.001 7 0 0 0 4.81E+07 1.93E+07 - - - 2.1895 0.9668 230117_WJC_METTL3_WT_vs_EV_F06.13687.13687.2 0.083 14-Jul R.DLAPIGIR.V "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 853.5022 0.9 47547 13687 2 853.504765 427.7584 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 5.84 2991.9 - 1.40E+06 - - - 3.0615 - 1.303 0.033 - 193.6 1 2 0 0.0026 8 0 0 0 1.97E+08 2.18E+08 - - - 0.0821 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.13695.13695.2 0.0293 14-Aug R.FAIYETVR[166.11].D "sp|Q9UBX3|DIC_HUMAN,tr|F6RGN5|F6RGN5_HUMAN,tr|I3L1E8|I3L1E8_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 4 1007.5316 1.03 47551 13695 2 1007.531023 504.7731 Mitochondrial dicarboxylate carrier OS=Homo sapiens OX=9606 GN=SLC25A10 PE=1 SV=2 6 2992.8 - 570522 - - - -0.525 - 1.667 0.317 - 179.9 1 2 0 -0.0005 8 0 0 0 2.15E+07 2.10E+07 - - - 2.9234 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.13699.13699.2 0.0217 20-Jun K.ITVTSEVPFSK.R "sp|P35268|RL22_HUMAN,tr|K7EKS7|K7EKS7_HUMAN,tr|K7ERI7|K7ERI7_HUMAN,tr|K7EMH1|K7EMH1_HUMAN,tr|K7ELC4|K7ELC4_HUMAN,tr|K7EP65|K7EP65_HUMAN,tr|K7EJT5|K7EJT5_HUMAN" 7 1206.6496 0.06 47555 13699 2 1206.651024 604.3321 60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2 6 2993.3 - 141293 - - - 1.1768 - 1.509 0.268 - 76.6 1 2 0 0.0014 11 0 0 0 2.11E+06 3.63E+07 - - - 2.1331 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.13709.13709.2 0.0101 24-Aug K.FC[160.03]ADSDGFSQELR[166.11].N "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1540.6492 0.21 47559 13709 2 1540.655053 771.3319 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.03 2994.7 - 87629.6 - - - 3.814 - 1.631 0.524 - 79.8 1 2 0 0.0059 13 0 0 0 3.98E+05 1.87E+06 - - - 4.1649 0.944 230117_WJC_METTL3_WT_vs_EV_F06.13725.13725.2 8.37 16-Jul M.ITEGAQAPR.L "sp|P27918|PROP_HUMAN,tr|E9PAQ1|E9PAQ1_HUMAN" 2 941.493 0.76 47569 13725 2 941.494702 471.7538 Properdin OS=Homo sapiens OX=9606 GN=CFP PE=1 SV=2 6 2996.7 - 253317 - - - 1.761 - 1.13 0.013 - 72 2 2 0 0.0017 9 0 0 0 1.40E+07 1.84E+07 - - - -0.6444 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.13729.13729.2 0.11 14-Jul K.AAFAPFGR.L "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 5 835.4341 1.32 47571 13729 2 835.435598 418.7243 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 9.79 2997.2 - 857813 - - - 1.8254 - 1.358 0.186 - 160.6 1 2 0 0.0015 8 0 0 0 2.20E+07 1.66E+07 - - - 1.3372 0.9951 230117_WJC_METTL3_WT_vs_EV_F06.13737.13737.2 1.23 14-Jun K.AAFAPFGR[166.11].L "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 5 845.4423 1.34 47577 13737 2 845.444534 423.7284 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 9.79 2998.1 - 356095 - - - 2.5915 - 1.208 0.226 - 93.9 1 2 0 0.0022 8 0 0 0 2.25E+07 1.68E+07 - - - 1.2795 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.13740.13740.2 0.0419 18-Sep K.TEVNSGFFYK.T "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN,tr|J3KRI6|J3KRI6_HUMAN" 3 1190.5608 34.36 47580 13740 2 1190.56407 596.2877 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.66 2998.4 - 168159 - - - 2.7558 - 1.754 0.336 - 147.4 1 2 0 0.0033 10 0 0 0 5.23E+06 1.52E+05 - - - 3.0901 0.9161 230117_WJC_METTL3_WT_vs_EV_F06.13755.13755.2 0.182 14-Aug F.GPVLNYLR[166.11].H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 940.537 0.82 47589 13755 2 940.538751 471.2758 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3000.1 - 646185 - - - 1.8925 - 1.868 0.188 - 252.3 1 1 0 0.0018 8 0 0 0 3.70E+07 4.48E+07 - - - 2.3136 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.13758.13758.2 0.0981 14-Sep R.NLLSVAYK.N "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB2|A2IDB2_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|K7EIT4|K7EIT4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 22 906.5175 1.55 47591 13758 2 906.519193 454.266 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 8.59 3000.5 - 8.94E+06 - - - 1.9029 - 1.632 0.226 - 317.1 1 2 0 0.0017 8 0 0 0 4.72E+08 3.05E+08 - - - 2.1869 0.999 230117_WJC_METTL3_WT_vs_EV_F06.13768.13768.2 0.0308 14-Jul R.FLGC[160.03]VDIK.D "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 950.4895 1.58 47597 13768 2 950.49194 476.252 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 5.83 3001.6 - 1.39E+06 - - - 2.5261 - 1.332 0.385 - 133.7 1 2 0 0.0024 8 0 0 0 3.47E+07 2.19E+07 - - - 2.7485 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.13769.13769.2 0.0977 14-Jul R.LYELDGLR.E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 977.5182 0.02 47598 13769 2 977.518123 489.7664 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3001.7 - 253015 - - - -0.0747 - 1.426 0.268 - 111.4 2 2 0 -0.0001 8 0 0 0 2.43E+06 1.43E+08 - - - 1.9562 0.9944 230117_WJC_METTL3_WT_vs_EV_F06.13772.13772.3 0.133 Oct-36 R.MVNHFIAEFK.R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1234.6169 9.43 47599 13772 3 1234.619765 412.5462 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 3002.1 - 1.26E+06 - - - 2.3489 - 1.672 0.177 - 94.3 1 2 0 0.0029 10 0 0 0 3.84E+07 4.07E+06 - - - 2.0137 0.9829 230117_WJC_METTL3_WT_vs_EV_F06.13785.13785.2 2.99 14-Jun R.FLGC[160.03]VDIK[136.11].D "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 958.5037 1.89 47608 13785 2 958.505183 480.2591 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 5.83 3003.6 - 640711 - - - 1.5065 - 1.11 0.102 - 81.8 1 2 0 0.0014 8 0 0 0 3.41E+07 1.80E+07 - - - 0.1087 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.13791.13791.2 0.00309 16-Oct K.VPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1071.5601 1.7 47612 13791 2 1071.563593 536.7873 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 3004.4 - 512983 - - - 3.2961 - 1.464 0.343 - 293 1 2 0 0.0035 9 0 0 0 1.55E+07 9.16E+06 - - - 2.676 0.9926 230117_WJC_METTL3_WT_vs_EV_F06.13792.13792.2 0.109 12-Jul R.ISPLQFR.- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 859.4916 2.88 47613 13792 2 859.493213 430.7531 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 3004.4 - 6.65E+06 - - - 1.8907 - 1.442 0.073 - 225.5 1 2 0 0.0016 7 0 0 0 3.34E+08 1.16E+08 - - - 0.7395 0.9825 230117_WJC_METTL3_WT_vs_EV_F06.13799.13799.2 0.657 12-Jun R.ISPLQFR[166.11].- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 869.4999 2.88 47618 13799 2 869.502417 435.7572 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 3005.2 - 2.64E+06 - - - 2.9431 - 1.331 0.072 - 129.2 1 2 0 0.0026 7 0 0 0 3.37E+08 1.17E+08 - - - 0.478 0.9855 230117_WJC_METTL3_WT_vs_EV_F06.13802.13802.2 0.018 18-Aug K.ILAEESYLYK.H sp|Q9NVX0|HAUS2_HUMAN 1 1227.6387 2.21 47621 13802 2 1227.647056 614.8266 HAUS augmin-like complex subunit 2 OS=Homo sapiens OX=9606 GN=HAUS2 PE=1 SV=1 4.53 3005.5 - 168110 - - - 6.8025 - 1.513 0.367 - 156.8 1 2 0 0.0083 10 0 0 0 4.05E+06 1.84E+06 - - - 2.9049 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.13805.13805.2 0.516 12-Jun K.LVYILNR[166.11].D sp|Q15393|SF3B3_HUMAN 1 899.5468 1.46 47622 13805 2 899.54813 450.7807 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 3006 - 5.47E+06 - - - 1.4696 - 1.462 0.17 - 117.7 1 2 0 0.0013 7 0 0 0 2.88E+08 1.97E+08 - - - 1.4996 0.9903 230117_WJC_METTL3_WT_vs_EV_F06.13807.13807.2 0.109 14-Jun K.DVSGIFIR.S sp|Q8NDH2|CC168_HUMAN 1 905.4971 1.65 47624 13807 2 905.497395 453.7558 Coiled-coil domain-containing protein 168 OS=Homo sapiens OX=9606 GN=CCDC168 PE=2 SV=2 5.84 3006.1 - 439933 - - - 0.3622 - 1.311 0.135 - 63.3 3 2 0 0.0003 8 0 0 0 2.13E+07 1.29E+07 - - - 0.6416 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.13809.13809.2 0.00894 22-Sep R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 2.63 47626 13809 2 1343.711244 672.8615 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 3006.4 - 363712 - - - 2.0302 - 1.876 0.348 - 92.7 1 2 0 0.0027 12 0 0 0 1.27E+07 4.82E+06 - - - 3.2659 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.13810.13810.2 0.0143 12-Jul R.YYFEGIK[136.11].Q "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN" 3 926.4629 2.67 47627 13810 2 926.462482 464.2387 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 6 3006.5 - 345015 - - - -0.4728 - 1.409 0.347 - 130.2 1 2 0 -0.0004 7 0 0 0 4.62E+07 1.73E+07 - - - 2.6902 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.13815.13815.2 0.574 12-Jul K.LVYILNR.D sp|Q15393|SF3B3_HUMAN 1 889.5385 1.48 47630 13815 2 889.54085 445.7765 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 3007.2 - 8.90E+06 - - - 2.5991 - 1.355 0.246 - 191.1 1 2 0 0.0023 7 0 0 0 2.93E+08 1.98E+08 - - - 1.8198 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.13817.13817.2 0.00257 16-Sep K.YDGIILPGK.- "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 974.5437 1.35 47632 13817 2 974.547226 488.2791 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.83 3007.5 - 507267 - - - 3.6355 - 1.573 0.36 - 249.8 1 2 0 0.0035 9 0 0 0 3.33E+07 2.47E+07 - - - 3.0094 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.13824.13824.2 0.0376 14-Aug K.VGVNGFGR.L sp|P04406|G3P_HUMAN 1 804.4242 2.89 47636 13824 2 804.425812 403.2194 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 3008.3 - 636591 - - - 1.9592 - 1.578 0.388 - 179.7 1 2 0 0.0016 8 0 0 0 4.46E+07 1.54E+07 - - - 3.282 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.13830.13830.2 0.612 14-Jun K.VLVPQIPR[166.11].L sp|Q10469|MGAT2_HUMAN 1 930.589 1.08 47640 13830 2 930.590777 466.3018 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 3009 - 785797 - - - 1.902 - 1.357 0.209 - 101 2 2 0 0.0018 8 0 0 0 1.02E+08 9.44E+07 - - - 1.3703 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.13835.13835.2 0.00288 14-Sep K.ITAFIVER.D "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 947.544 0.52 47643 13835 2 947.546405 474.7793 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 6 3009.6 - 1.51E+06 - - - 2.5202 - 1.79 0.344 - 208.4 1 2 0 0.0024 8 0 0 0 5.33E+07 1.03E+08 - - - 3.337 0.9861 230117_WJC_METTL3_WT_vs_EV_F06.13836.13836.2 0.068 14-Jun K.VLVPQIPR.L sp|Q10469|MGAT2_HUMAN 1 920.5807 1.08 47644 13836 2 920.582729 461.2976 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 3009.7 - 816143 - - - 2.1639 - 1.072 0.168 - 85.7 2 2 0 0.002 8 0 0 0 1.02E+08 9.44E+07 - - - 0.3564 0.9928 230117_WJC_METTL3_WT_vs_EV_F06.13837.13837.2 0.23 12-Aug K.FTAILYR.T "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 882.4963 0.61 47645 13837 2 882.499871 442.2554 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.75 3009.8 - 3.75E+06 - - - 4.0023 - 1.625 0.152 - 288.2 1 2 0 0.0035 7 0 0 0 1.17E+08 1.91E+08 - - - 1.7009 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.13839.13839.2 0.00418 14-Aug K.IDVAFVDR.A sp|Q15645|PCH2_HUMAN 1 933.492 1.78 47647 13839 2 933.493718 467.7533 Pachytene checkpoint protein 2 homolog OS=Homo sapiens OX=9606 GN=TRIP13 PE=1 SV=2 4.21 3010 - 416868 - - - 1.8597 - 1.789 0.393 - 147.4 1 2 0 0.0017 8 0 0 0 2.51E+07 1.41E+07 - - - 3.6974 0.9881 230117_WJC_METTL3_WT_vs_EV_F06.13844.13844.2 17.2 12-Jul R.LVQLLVK.A sp|P14923|PLAK_HUMAN 1 811.5531 17.57 47650 13844 2 811.555037 406.7838 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 8.75 3010.6 - 1.74E+06 - - - 2.356 - 1.322 0.081 - 101.7 1 2 0 0.0019 7 0 0 0 2.57E+08 1.47E+07 - - - 0.5232 0.998 230117_WJC_METTL3_WT_vs_EV_F06.13845.13845.2 0.0176 12-Jun K.FYIDPYK[136.11].L sp|Q9NY12|GAR1_HUMAN 1 952.4786 0.81 47651 13845 2 952.48144 477.2466 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3010.7 - 1.12E+06 - - - 3.0132 - 1.375 0.302 - 143.1 1 2 0 0.0029 7 0 0 0 1.25E+09 1.55E+09 - - - 2.2797 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.13851.13851.2 0.119 16-Aug R.VLLLEAGPK.D "sp|Q8NE62|CHDH_HUMAN,tr|C9J7D8|C9J7D8_HUMAN,tr|C9JYW4|C9JYW4_HUMAN" 3 938.5801 4.87 47654 13851 2 938.582419 470.2973 "Choline dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=CHDH PE=1 SV=2" 5.97 3011.5 - 452175 - - - 2.5048 - 1.378 0.213 - 155.6 1 2 0 0.0024 9 0 0 0 1.71E+07 3.51E+06 - - - 1.5411 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.13852.13852.2 1.07 18-Oct R.YPVNSVNILK.A "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1145.6445 30.51 47655 13852 2 1145.64733 573.8295 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.59 3011.6 - 360513 - - - 2.506 - 1.92 0.237 - 154.1 1 2 0 0.0029 10 0 0 0 1.85E+07 6.07E+05 - - - 2.6114 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.13859.13859.2 0.0158 14-Jun R.VIFTSPIK[136.11].A sp|P42285|MTREX_HUMAN 1 911.5572 1.04 47660 13859 2 911.559025 456.7859 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 8.72 3012.4 - 1.05E+06 - - - 2.0525 - 1.319 0.243 - 107.6 1 2 0 0.0019 8 0 0 0 1.12E+08 1.08E+08 - - - 1.6702 0.9947 230117_WJC_METTL3_WT_vs_EV_F06.13875.13875.2 0.104 16-Jul R.VPPEFLVQR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1093.616 1.28 47669 13875 2 1093.618017 547.8153 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3014.4 - 260103 - - - 1.8901 - 1.292 0.163 - 133.2 1 2 0 0.0021 9 0 0 0 4.66E+07 3.65E+07 - - - 0.9854 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.13887.13887.2 0.0348 16-Jul K.YDGIILPGK[136.11].- "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 982.5579 1.35 47677 13887 2 982.559542 492.2862 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.83 3015.9 - 452806 - - - 1.6885 - 1.113 0.303 - 128.2 1 2 0 0.0017 9 0 0 0 3.33E+07 2.47E+07 - - - 1.5882 0.9942 230117_WJC_METTL3_WT_vs_EV_F06.13892.13892.2 0.32 14-Jul R.LPWAVAGR.S sp|Q8NBX0|SCPDL_HUMAN 1 868.4919 1.89 47680 13892 2 868.492641 435.2532 Saccharopine dehydrogenase-like oxidoreductase OS=Homo sapiens OX=9606 GN=SCCPDH PE=1 SV=1 9.75 3016.5 - 976115 - - - 0.8279 - 1.372 0.123 - 149.2 1 2 0 0.0007 8 0 0 0 6.64E+07 3.50E+07 - - - 0.9031 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.13895.13895.2 0.00109 12-Jul K.LFEMAYK.K "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 900.4415 4.44 47681 13895 2 900.443015 451.228 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6 3016.9 - 8.06E+06 - - - 1.6536 - 1.455 0.412 - 181 1 2 0 0.0015 7 0 0 0 1.29E+09 2.90E+08 - - - 3.2718 0.9312 230117_WJC_METTL3_WT_vs_EV_F06.13914.13914.2 2.01 12-Jul R.NLVYTVK.L sp|Q2M385|MPEG1_HUMAN 1 835.4804 0.6 47693 13914 2 835.482384 418.7475 Macrophage-expressed gene 1 protein OS=Homo sapiens OX=9606 GN=MPEG1 PE=1 SV=1 8.59 3019.1 - 402885 - - - 2.4297 - 1.075 0.032 - 112.4 2 2 0 0.002 7 0 0 0 2.97E+07 4.98E+07 - - - -0.6286 0.9335 230117_WJC_METTL3_WT_vs_EV_F06.13921.13921.2 2.76 16-Aug R.IIFSPVAPK.E sp|O15294|OGT1_HUMAN 1 970.5852 1.32 47697 13921 2 970.58987 486.2999 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 8.75 3019.9 - 929647 - - - 4.8589 - 1.384 0.057 - 157.6 1 2 0 0.0047 9 0 0 0 9.28E+07 7.01E+07 - - - 0.4007 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.13922.13922.2 0.00474 13/18 K.VLQSALAAIR.H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1040.6342 1.02 47698 13922 2 1040.636528 521.3244 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 3020 - 616786 - - - 2.2092 - 2.358 0.34 - 512.7 1 2 0 0.0023 10 0 0 0 2.70E+08 2.64E+08 - - - 3.9459 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.13925.13925.2 0.0339 18-Oct R.VLAESLGPLR.E sp|Q4KMQ1|TPRN_HUMAN 1 1053.6182 1.35 47699 13925 2 1053.616579 527.8164 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 5.97 3020.4 - 852428 - - - -1.5812 - 1.841 0.267 - 215.1 1 2 0 -0.0017 10 0 0 0 5.90E+07 4.37E+07 - - - 2.7161 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.13927.13927.2 0.773 18-Aug K.VLQSALAAIR[166.11].H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1050.6425 1.02 47701 13927 2 1050.643765 526.3285 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 3020.6 - 1.48E+06 - - - 1.205 - 2.047 0.062 - 185.5 3 2 0 0.0013 10 0 0 0 2.70E+08 2.64E+08 - - - 1.285 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.13941.13941.2 0.0486 14-Sep K.IAADILIK.E "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 855.543 0.87 47708 13941 2 855.542086 428.7788 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.84 3022.3 - 619894 - - - -1.0146 - 1.581 0.269 - 142.5 1 2 0 -0.0009 8 0 0 0 1.62E+07 1.87E+07 - - - 2.409 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.13943.13943.2 0.105 14-Jul R.YPEEFALR.D "sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN" 4 1023.5025 0.44 47709 13943 2 1023.504475 512.7585 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.53 3022.5 - 382948 - - - 1.8847 - 1.169 0.293 - 139 1 2 0 0.0019 8 0 0 0 1.67E+07 3.81E+07 - - - 1.6754 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.13950.13950.2 0.00202 16-Aug R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 999 47714 13950 2 1030.592152 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 3023.4 - 2.90E+07 - - - 1.0916 - 1.827 0.206 - 177 1 2 0 0.0011 9 0 0 0 4.58E+09 0.00E+00 - - - 2.3057 0.9679 230117_WJC_METTL3_WT_vs_EV_F06.13954.13954.2 2.19 12-Jun K.TISLVIR[166.11].G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 810.5203 1.57 47716 13954 2 810.520966 406.2674 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 9.41 3024 - 678766 - - - 0.8723 - 1.17 0.025 - 101.2 1 2 0 0.0007 7 0 0 0 5.47E+07 3.49E+07 - - - -0.2771 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.13959.13959.2 0.0153 18-Nov K.LAEALYIADR.K "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1133.6081 1.4 47717 13959 2 1133.609459 567.8113 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 3024.7 - 211652 - - - 1.2218 - 2.524 0.34 - 405.9 1 2 0 0.0014 10 0 0 0 5.96E+07 4.25E+07 - - - 4.1361 0.9946 230117_WJC_METTL3_WT_vs_EV_F06.13960.13960.2 0.123 18-Sep K.LAEALYIADR[166.11].K "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1143.6163 1.67 47718 13960 2 1143.615596 572.8154 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 3024.9 - 131345 - - - -0.6541 - 1.949 0.084 - 209.8 1 2 0 -0.0007 10 0 0 0 5.92E+07 3.54E+07 - - - 1.5239 0.955 230117_WJC_METTL3_WT_vs_EV_F06.13965.13965.2 0.697 12-May R.FPPYYMR[166.11].R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 982.461 0.92 47720 13965 2 982.463338 492.2378 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 3025.6 - 299303 - - - 2.3502 - 0.862 0.143 - 62.4 1 2 0 0.0023 7 0 0 0 1.31E+07 1.42E+07 - - - -0.3741 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.13968.13968.2 0.0163 14-Jun R.VVIQEMLK.T sp|P40938|RFC3_HUMAN 1 958.5521 1.92 47722 13968 2 958.552948 480.2833 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 5.97 3025.9 - 1.83E+06 - - - 0.844 - 1.286 0.195 - 108.4 1 2 0 0.0008 8 0 0 0 4.67E+07 2.43E+07 - - - 1.2396 0.913 230117_WJC_METTL3_WT_vs_EV_F06.13982.13982.2 0.0672 12-Jun K.SAEFLLH.M "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 815.4178 - 47730 13982 2 815.418311 408.7162 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 5.22 3027.7 - 1.91E+06 - - - 0.6831 - 1.347 0.313 - 184.8 1 1 0 0.0006 7 0 0 0 - - - - - 2.2965 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.13986.13986.2 0.00495 16-Aug K.FTPGAVMLR.V "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 990.5321 1.69 47734 13986 2 990.535606 496.2733 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.75 3028.1 - 479434 - - - 3.5678 - 1.577 0.397 - 197.2 1 2 0 0.0035 9 0 0 0 5.08E+07 3.01E+07 - - - 3.29 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.13990.13990.2 0.000503 14-Jul R.VLVLVPTR[166.11].E "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 905.5938 0.9 47736 13990 2 905.594767 453.8042 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 9.72 3028.6 - 1.49E+06 - - - 1.1142 - 1.687 0.22 - 210.1 1 2 0 0.001 8 0 0 0 7.00E+07 7.78E+07 - - - 2.2428 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.13995.13995.2 0.000893 18-Aug K.NLQEAEEWYK.S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1308.5986 1.85 47741 13995 2 1308.60176 655.3066 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3029.1 - 297413 - - - 2.3903 - 1.904 0.404 - 179.6 1 2 0 0.0031 10 0 0 0 2.18E+07 1.18E+07 - - - 3.8214 0.9412 230117_WJC_METTL3_WT_vs_EV_F06.14001.14001.2 0.0304 12-Aug R.LFVLTTK.N sp|Q96RS6|NUDC1_HUMAN 1 820.5058 2.36 47745 14001 2 820.511079 411.2602 NudC domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NUDCD1 PE=1 SV=2 8.75 3029.9 - 391967 - - - 6.3839 - 1.564 0.108 - 189.6 1 2 0 0.0052 7 0 0 0 3.81E+07 1.61E+07 - - - 1.2542 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.14006.14006.2 0.0513 18-Oct K.NLQEAEEWYK[136.11].S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1316.6128 1.87 47747 14006 2 1316.615908 659.3137 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3030.6 - 455191 - - - 2.3363 - 1.683 0.371 - 282 1 2 0 0.0031 10 0 0 0 2.20E+07 1.18E+07 - - - 3.2333 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.14007.14007.2 3.35E-05 28-Oct K.NQVALNPQNTVFDAK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1657.8424 999 47748 14007 2 1657.848292 829.9285 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3030.8 - 205557 - - - 3.5637 - 2.157 0.478 - 218.5 1 2 0 0.0059 15 0 0 0 5.60E+06 0.00E+00 - - - 4.4596 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.14013.14013.2 0.000143 14-Jul R.VLVLVPTR.E "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 895.5855 0.9 47751 14013 2 895.586705 448.8 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 9.72 3031.4 - 2.33E+06 - - - 1.3589 - 1.689 0.296 - 193 1 2 0 0.0012 8 0 0 0 7.00E+07 7.78E+07 - - - 2.8076 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.14021.14021.2 0.0418 14-Aug R.VWAEYALK[136.11].R sp|Q6P2Q9|PRP8_HUMAN 1 986.5317 1.27 47757 14021 2 986.532952 494.2731 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3032.2 - 1.86E+06 - - - 1.3015 - 1.614 0.384 - 257.7 1 2 0 0.0013 8 0 0 0 2.71E+08 2.13E+08 - - - 3.3206 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.14023.14023.2 0.0724 16-Jul K.FTPGAVMLR[166.11].V "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1000.5403 2.07 47759 14023 2 1000.542353 501.2774 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.75 3032.5 - 808440 - - - 2.0099 - 1.401 0.241 - 119.2 2 2 0 0.002 9 0 0 0 4.74E+07 2.29E+07 - - - 1.6614 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.14026.14026.2 0.065 14-Aug R.LPLATIVK.D sp|O94776|MTA2_HUMAN 1 853.5637 1.5 47760 14026 2 853.565055 427.7891 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 3032.9 - 697747 - - - 1.5992 - 1.567 0.317 - 142.4 1 2 0 0.0014 8 0 0 0 2.61E+08 1.74E+08 - - - 2.7366 0.999 230117_WJC_METTL3_WT_vs_EV_F06.14028.14028.2 0.0113 14-Aug K.IDNIVLMK[136.11].D "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 952.5507 2.78 47761 14028 2 952.551184 477.2826 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 5.84 3033.1 - 1.42E+06 - - - 0.5197 - 1.672 0.264 - 142 1 2 0 0.0005 8 0 0 0 1.21E+08 4.35E+07 - - - 2.541 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.14031.14031.2 0.098 14-Aug R.EAVLSLYR.A sp|L0R8F8|MIDUO_HUMAN 1 949.5233 1.02 47763 14031 2 949.524637 475.7689 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 6.1 3033.4 - 1.78E+06 - - - 1.427 - 1.56 0.296 - 212.7 1 2 0 0.0014 8 0 0 0 5.77E+07 5.68E+07 - - - 2.568 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.14041.14041.2 0.0104 14-Aug K.LYLADPMK.A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 949.4943 1.58 47766 14041 2 949.49311 475.7544 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 3034.8 - 1.88E+06 - - - -1.2428 - 1.473 0.38 - 184.6 1 2 0 -0.0012 8 0 0 0 3.25E+08 2.06E+08 - - - 3.0154 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.14050.14050.2 0.00573 14-Aug K.LYLADPMK[136.11].A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 957.5085 1.57 47771 14050 2 957.508512 479.7615 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 3035.8 - 2.41E+06 - - - 0.023 - 1.588 0.374 - 212.4 1 2 0 0 8 0 0 0 3.25E+08 2.06E+08 - - - 3.1982 0.9947 230117_WJC_METTL3_WT_vs_EV_F06.14059.14059.2 3.63 12-Jul K.IISIIVK.N "sp|Q9Y4A5|TRRAP_HUMAN,sp|Q6PEY0|CXB7_HUMAN,sp|Q96QE4|LR37B_HUMAN,tr|J3QSU1|J3QSU1_HUMAN,tr|J3KTP0|J3KTP0_HUMAN,tr|A0A0A0MRM5|A0A0A0MRM5_HUMAN,tr|J3QLI7|J3QLI7_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 9 784.5422 1.34 47774 14059 2 784.543819 393.2784 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3037 - 1.11E+06 - - - 2.0305 - 1.574 0.074 - 118.9 1 2 0 0.0016 7 0 0 0 2.59E+07 1.93E+07 - - - 1.0244 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.14064.14064.2 0.597 14-Aug R.ALVLAQIR.K "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHA0|A0A6Q8PHA0_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF69|A0A6Q8PF69_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PGR0|A0A6Q8PGR0_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN,tr|A0A6Q8PFN8|A0A6Q8PFN8_HUMAN" 16 882.5651 1.78 47777 14064 2 882.564951 442.2898 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 9.79 3037.5 - 575005 - - - -0.1541 - 1.599 0.235 - 202.9 1 2 0 -0.0001 8 0 0 0 2.10E+07 1.18E+07 - - - 2.1923 1 230117_WJC_METTL3_WT_vs_EV_F06.14067.14067.2 9.38E-06 18-Dec R.VPLVAPEDLR[166.11].D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1117.6371 0.5 47778 14067 2 1117.637907 559.8258 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3037.9 - 760756 - - - 0.7408 - 2.55 0.42 - 626.8 1 2 0 0.0008 10 0 0 0 7.93E+08 1.60E+09 - - - 4.7558 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.14068.14068.2 0.0608 14-Jul K.FVDGEWYR.A sp|Q7KZF4|SND1_HUMAN 1 1070.4821 1.1 47779 14068 2 1070.482525 536.2483 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.37 3038.1 - 768963 - - - 0.355 - 1.092 0.28 - 146.9 1 2 0 0.0004 8 0 0 0 1.01E+07 9.19E+06 - - - 1.3744 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.14075.14075.2 0.0219 12-Aug R.FTDILVR.H sp|O43143|DHX15_HUMAN 1 862.4913 1.06 47783 14075 2 862.491292 432.2529 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 3038.9 - 4.94E+06 - - - 0.0452 - 1.561 0.352 - 223.5 1 2 0 0 7 0 0 0 6.36E+08 5.97E+08 - - - 3.0519 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.14080.14080.2 0.207 12-Jul K.LYLEQLR.Q sp|O43818|U3IP2_HUMAN 1 933.5284 0.72 47787 14080 2 933.529578 467.7715 U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens OX=9606 GN=RRP9 PE=1 SV=1 6 3039.5 - 5.85E+06 - - - 1.2972 - 1.344 0.167 - 219.2 1 2 0 0.0012 7 0 0 0 1.37E+08 1.91E+08 - - - 1.2109 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.14082.14082.2 0.0792 18-Oct R.VPLVAPEDLR.D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1107.6288 0.5 47789 14082 2 1107.628582 554.8217 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3039.7 - 1.12E+06 - - - -0.2049 - 2.236 0.39 - 463.5 1 2 0 -0.0002 10 0 0 0 7.91E+08 1.59E+09 - - - 4.1676 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.14085.14085.2 0.00547 12-Aug R.VFDMLNR[166.11].R "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 12 903.4512 1.56 47792 14085 2 903.452232 452.7329 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3040.1 - 616397 - - - 1.15 - 1.707 0.372 - 224.8 1 2 0 0.001 7 0 0 0 7.88E+07 5.04E+07 - - - 3.4826 1 230117_WJC_METTL3_WT_vs_EV_F06.14092.14092.2 1.47E-06 20-Nov K.YFVEAGAMAVR.R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1212.5961 10.01 47797 14092 2 1212.60097 607.3053 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3040.9 - 517274 - - - 3.9923 - 2.185 0.573 - 326 1 2 0 0.0048 11 0 0 0 7.28E+08 7.27E+07 - - - 5.3861 0.8605 230117_WJC_METTL3_WT_vs_EV_F06.14093.14093.2 1.5 12-Jun H.EPLGLLR.G sp|Q5W0U4|BSPRY_HUMAN 1 796.4807 3.25 47798 14093 2 796.481922 399.2476 B box and SPRY domain-containing protein OS=Homo sapiens OX=9606 GN=BSPRY PE=2 SV=1 6.1 3041 - 1.64E+06 - - - 1.5481 - 1.381 0.223 - 141.8 1 1 0 0.0012 7 0 0 0 8.50E+07 2.62E+07 - - - 1.7105 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.14103.14103.2 0.000768 20-Oct K.YFVEAGAMAVR[166.11].R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1222.6044 10.01 47801 14103 2 1222.604013 612.3095 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3042.4 - 247158 - - - -0.3157 - 1.707 0.469 - 358.3 1 2 0 -0.0004 11 0 0 0 7.28E+08 7.27E+07 - - - 3.9515 0.9851 230117_WJC_METTL3_WT_vs_EV_F06.14107.14107.2 2.23 12-Jul K.LYFNSLR.T "sp|Q9P0J1|PDP1_HUMAN,tr|E5RIV4|E5RIV4_HUMAN" 2 911.4865 6.55 47804 14107 2 911.489237 456.7505 "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PDP1 PE=1 SV=3" 8.75 3042.9 - 302655 - - - 3.0006 - 1.251 0.117 - 111.6 1 2 0 0.0027 7 0 0 0 2.93E+07 4.47E+06 - - - 0.6139 0.999 230117_WJC_METTL3_WT_vs_EV_F06.14111.14111.2 0.0032 26-Aug K.IFVGGLSPDTPEEK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1487.7508 1.5 47805 14111 2 1487.755921 744.8827 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3043.5 - 104155 - - - 3.4589 - 1.669 0.432 - 81.7 1 2 0 0.0051 14 0 0 0 9.29E+06 6.20E+06 - - - 3.5155 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.14113.14113.2 0.0111 16-Aug R.VPPEFLVQR.A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1083.6077 1.61 47806 14113 2 1083.609968 542.8111 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3043.7 - 610244 - - - 2.1115 - 1.433 0.265 - 220.2 1 2 0 0.0023 9 0 0 0 3.28E+07 2.04E+07 - - - 2.0384 0.9953 230117_WJC_METTL3_WT_vs_EV_F06.14124.14124.2 0.227 12-Aug K.IAWALSR.K sp|Q04760|LGUL_HUMAN 1 815.4654 1.07 47811 14124 2 815.465576 408.74 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 9.75 3045.1 - 1.88E+06 - - - 0.2489 - 1.623 0.087 - 231.1 1 2 0 0.0002 7 0 0 0 1.11E+08 1.04E+08 - - - 1.218 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.14135.14135.2 0.438 12-Jul R.SLEVILR[166.11].A sp|Q14566|MCM6_HUMAN 1 838.5152 1.05 47817 14135 2 838.515923 420.2649 DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1 5.72 3046.4 - 1.01E+06 - - - 0.8944 - 1.389 0.186 - 168.2 1 2 0 0.0008 7 0 0 0 5.61E+07 5.32E+07 - - - 1.4557 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.14136.14136.2 0.0611 18-Aug R.VPYVIISAAK.G "sp|P28340|DPOD1_HUMAN,tr|M0QXQ2|M0QXQ2_HUMAN,tr|M0QXE6|M0QXE6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 5 1059.6328 1.88 47818 14136 2 1059.635288 530.8237 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.56 3046.6 - 244888 - - - 2.3178 - 1.593 0.195 - 165.9 1 2 0 0.0025 10 0 0 0 9.61E+06 5.12E+06 - - - 1.7802 1 230117_WJC_METTL3_WT_vs_EV_F06.14137.14137.2 8.31E-07 26-Oct K.IFVGGLSPDTPEEK[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1495.765 1.5 47819 14137 2 1495.76921 748.8898 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3046.7 - 271563 - - - 2.8313 - 2.105 0.593 - 242 1 2 0 0.0042 14 0 0 0 9.29E+06 6.20E+06 - - - 5.2874 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.14142.14142.2 0.0495 16-Nov K.LADMGIAIR[166.11].V sp|Q9Y3I0|RTCB_HUMAN 1 968.5353 1.27 47822 14142 2 968.537044 485.2749 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.84 3047.4 - 1.80E+06 - - - 1.8451 - 2.104 0.197 - 442 1 2 0 0.0018 9 0 0 0 2.30E+08 1.81E+08 - - - 2.6475 0.9965 230117_WJC_METTL3_WT_vs_EV_F06.14145.14145.2 0.162 16-Aug R.VPPEFLVQR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1093.616 1.63 47825 14145 2 1093.617596 547.8153 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3047.8 - 330141 - - - 1.5051 - 1.197 0.229 - 195 1 2 0 0.0016 9 0 0 0 3.13E+07 1.92E+07 - - - 1.2521 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.14153.14153.2 0.0714 12-Jun R.FTDILVR[166.11].H sp|O43143|DHX15_HUMAN 1 872.4995 1.06 47830 14153 2 872.500698 437.257 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 3048.8 - 4.34E+06 - - - 1.3467 - 1.364 0.292 - 117 1 2 0 0.0012 7 0 0 0 6.36E+08 5.97E+08 - - - 2.1809 0.9879 230117_WJC_METTL3_WT_vs_EV_F06.14156.14156.2 0.448 12-Jul R.SLILAMK[136.11].A sp|Q7Z353|HDX_HUMAN 1 782.4815 0.53 47832 14156 2 782.483439 392.248 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 8.47 3049.1 - 1.29E+06 - - - 2.4179 - 1.408 0.055 - 206.6 1 2 0 0.0019 7 0 0 0 1.67E+07 3.15E+07 - - - 0.5308 0.9909 230117_WJC_METTL3_WT_vs_EV_F06.14157.14157.2 2.54 14-Aug K.LLGPVLVK.Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 837.5688 3.86 47833 14157 2 837.570066 419.7917 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 3049.1 - 2.18E+06 - - - 1.5414 - 1.295 0.098 - 126.9 1 2 0 0.0013 8 0 0 0 9.64E+08 2.50E+08 - - - 0.5441 0.9764 230117_WJC_METTL3_WT_vs_EV_F06.14166.14166.2 8.95 14-Jul K.LLGPVLVK[136.11].Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 845.583 3.86 47838 14166 2 845.583949 423.7988 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 3050.3 - 1.39E+06 - - - 1.1519 - 1.149 0.059 - 84 1 2 0 0.001 8 0 0 0 9.64E+08 2.50E+08 - - - -0.1046 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.14168.14168.2 0.335 16-Aug K.LFGETTLVK.S sp|P50748|KNTC1_HUMAN 1 1006.5699 0.86 47840 14168 2 1006.571662 504.2922 Kinetochore-associated protein 1 OS=Homo sapiens OX=9606 GN=KNTC1 PE=1 SV=1 6 3050.5 - 353017 - - - 1.7525 - 1.333 0.23 - 117.8 1 2 0 0.0018 9 0 0 0 8.10E+06 9.37E+06 - - - 1.5708 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.14173.14173.2 0.0521 14-Jul R.LPLATIVK[136.11].D sp|O94776|MTA2_HUMAN 1 861.5779 1.5 47843 14173 2 861.579104 431.7962 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 3051.1 - 2.74E+06 - - - 1.409 - 1.461 0.323 - 138.7 1 2 0 0.0012 8 0 0 0 2.61E+08 1.74E+08 - - - 2.5697 0.9632 230117_WJC_METTL3_WT_vs_EV_F06.14178.14178.2 0.702 12-Jun R.VFDMLNR.R "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 12 893.4429 1.56 47846 14178 2 893.443473 447.7287 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3051.8 - 242223 - - - 0.6156 - 1.206 0.024 - 81.2 2 2 0 0.0006 7 0 0 0 7.86E+07 5.05E+07 - - - -0.3229 1 230117_WJC_METTL3_WT_vs_EV_F06.14180.14180.2 0.00999 13/22 K.SPILVATAVAAR[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1177.7058 1.12 47848 14180 2 1177.706595 589.8602 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3052 - 248480 - - - 0.6513 - 2.807 0.416 - 498.2 1 2 0 0.0008 12 0 0 0 7.44E+08 6.64E+08 - - - 4.829 0.9945 230117_WJC_METTL3_WT_vs_EV_F06.14194.14194.2 2.62 12-Aug R.QSILILK.E "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 3 813.5324 2.6 47856 14194 2 813.533209 407.7735 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 8.75 3053.8 - 2.09E+06 - - - 1.0067 - 1.295 0.144 - 189.4 1 2 0 0.0008 7 0 0 0 9.17E+07 3.53E+07 - - - 0.9234 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.14195.14195.2 0.043 16-Jul K.VLPLEEAYR.F sp|Q9H223|EHD4_HUMAN 1 1088.5866 1.73 47857 14195 2 1088.590731 545.3006 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 3053.9 - 284456 - - - 3.7856 - 1.462 0.317 - 140.5 1 2 0 0.0041 9 0 0 0 2.54E+08 1.46E+08 - - - 2.4799 0.9921 230117_WJC_METTL3_WT_vs_EV_F06.14196.14196.2 0.0239 18-Jul K.LFPGSPAIYK.L "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|F8W705|F8W705_HUMAN,tr|C9JF75|C9JF75_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|C9J6W1|C9J6W1_HUMAN,tr|H0YBN8|H0YBN8_HUMAN,tr|C9J1W9|C9J1W9_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 17 1091.6015 4.8 47858 14196 2 1091.604977 546.808 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 8.59 3054 - 320698 - - - 3.1559 - 1.248 0.203 - 101.9 1 2 0 0.0034 10 0 0 0 6.24E+07 1.30E+07 - - - 1.1577 0.9857 230117_WJC_METTL3_WT_vs_EV_F06.14201.14201.2 1.1 12-Jun R.LILPYER.F "sp|Q14865|ARI5B_HUMAN,tr|A0A7P0TAD2|A0A7P0TAD2_HUMAN" 2 902.5226 1.66 47861 14201 2 902.524137 452.2686 AT-rich interactive domain-containing protein 5B OS=Homo sapiens OX=9606 GN=ARID5B PE=1 SV=3 6 3054.7 - 866503 - - - 1.7551 - 1.127 0.113 - 128.2 1 2 0 0.0016 7 0 0 0 1.70E+07 1.02E+07 - - - 0.254 0.9959 230117_WJC_METTL3_WT_vs_EV_F06.14202.14202.2 0.146 14-Jun R.LLAMLEQK.N "sp|Q96EA4|SPDLY_HUMAN,tr|H0YBG5|H0YBG5_HUMAN" 2 944.5365 13.83 47862 14202 2 944.537863 473.2755 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 6 3054.7 - 1.08E+06 - - - 1.4547 - 1.215 0.203 - 73.5 1 2 0 0.0014 8 0 0 0 3.06E+07 2.21E+06 - - - 1.1273 0.9894 230117_WJC_METTL3_WT_vs_EV_F06.14203.14203.2 3.07 12-Jul R.QSILILK[136.11].E "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 3 821.5466 2.62 47863 14203 2 821.54742 411.7806 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 8.75 3054.8 - 1.07E+06 - - - 1.0103 - 1.212 0.108 - 105.2 1 2 0 0.0008 7 0 0 0 9.23E+07 3.53E+07 - - - 0.4477 0.9937 230117_WJC_METTL3_WT_vs_EV_F06.14210.14210.2 1.73 14-Aug K.GIGLAIVR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 807.5206 0.95 47868 14210 2 807.521045 404.7676 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 3055.5 - 644373 - - - 0.5597 - 1.418 0.109 - 204 1 2 0 0.0005 8 0 0 0 5.69E+08 5.97E+08 - - - 0.8992 1 230117_WJC_METTL3_WT_vs_EV_F06.14214.14214.2 0.000152 13/22 K.SPILVATAVAAR.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1167.6976 1.12 47870 14214 2 1167.699062 584.8561 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3056.1 - 2.64E+06 - - - 1.288 - 2.547 0.513 - 692.7 1 2 0 0.0015 12 0 0 0 7.44E+08 6.64E+08 - - - 5.2895 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.14221.14221.2 0.023 14-Aug R.VPDVVLIK.K "sp|Q96D46|NMD3_HUMAN,tr|C9JA08|C9JA08_HUMAN" 2 881.5586 2.49 47875 14221 2 881.559912 441.7866 60S ribosomal export protein NMD3 OS=Homo sapiens OX=9606 GN=NMD3 PE=1 SV=1 5.81 3056.9 - 845274 - - - 1.4826 - 1.399 0.302 - 152.9 1 2 0 0.0013 8 0 0 0 3.74E+07 1.50E+07 - - - 2.2838 0.976 230117_WJC_METTL3_WT_vs_EV_F06.14242.14242.2 0.0947 12-Jul K.IVQWDIR.S "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 928.5131 1.38 47891 14242 2 928.509782 465.2638 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.84 3059.2 - 921670 - - - -3.5207 - 1.508 0.197 - 140 1 2 0 -0.0033 7 0 0 0 1.31E+07 9.44E+06 - - - 1.7966 0.9814 230117_WJC_METTL3_WT_vs_EV_F06.14247.14247.2 0.395 12-May -.MFVSDFR.K "sp|O75419|CDC45_HUMAN,tr|A0A5F9ZH29|A0A5F9ZH29_HUMAN,tr|C9J911|C9J911_HUMAN,tr|C9K087|C9K087_HUMAN" 4 900.4164 1.45 47894 14247 2 900.415708 451.2155 Cell division control protein 45 homolog OS=Homo sapiens OX=9606 GN=CDC45 PE=1 SV=1 5.59 3059.9 - 374658 - - - -0.7397 - 1.095 0.174 - 62.5 1 2 0 -0.0007 7 0 0 0 1.48E+07 1.02E+07 - - - 0.6135 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.14250.14250.2 0.112 14-Aug R.LLLIATGK.R "sp|Q9NQW6|ANLN_HUMAN,tr|H7C1K5|H7C1K5_HUMAN" 2 827.548 0.05 47895 14250 2 827.548605 414.7813 Anillin OS=Homo sapiens OX=9606 GN=ANLN PE=1 SV=2 8.75 3060.2 - 1.36E+06 - - - 0.6827 - 1.711 0.112 - 204.3 1 2 0 0.0006 8 0 0 0 4.48E+07 8.54E+08 - - - 1.4879 0.997 230117_WJC_METTL3_WT_vs_EV_F06.14253.14253.2 0.191 16-Jul R.LAEYYGLYR.D sp|Q96DV4|RM38_HUMAN 1 1146.571 1.17 47898 14253 2 1146.569476 574.2928 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3060.6 - 352417 - - - -1.2943 - 1.766 0.243 - 161.5 1 2 0 -0.0015 9 0 0 0 6.77E+07 5.80E+07 - - - 2.4807 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.14256.14256.2 0.0338 16-Aug K.VLPLEEAYR[166.11].F sp|Q9H223|EHD4_HUMAN 1 1098.5949 1.76 47899 14256 2 1098.594631 550.3047 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 3061 - 2.00E+06 - - - -0.2267 - 1.336 0.221 - 222.8 1 2 0 -0.0002 9 0 0 0 2.53E+08 1.44E+08 - - - 1.5113 0.9955 230117_WJC_METTL3_WT_vs_EV_F06.14260.14260.2 0.292 16-Oct R.LAEYYGLYR[166.11].D sp|Q96DV4|RM38_HUMAN 1 1156.5792 1.17 47901 14260 2 1156.578847 579.2969 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3061.5 - 522110 - - - -0.3311 - 1.789 0.108 - 418.7 1 2 0 -0.0004 9 0 0 0 6.77E+07 5.80E+07 - - - 1.5213 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.14267.14267.2 0.00884 18-Sep K.LPAVVTADLR.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1053.6182 2.11 47904 14267 2 1053.620372 527.8164 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.84 3062.4 - 361064 - - - 2.0188 - 1.829 0.104 - 185.9 1 2 0 0.0021 10 0 0 0 1.01E+07 4.81E+06 - - - 1.4938 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.14270.14270.2 0.00133 14-Aug K.VITMFVQR[166.11].Q "sp|P13010|XRCC5_HUMAN,tr|C9JZ81|C9JZ81_HUMAN,tr|H7C0H9|H7C0H9_HUMAN" 3 1002.556 0.79 47906 14270 2 1002.557608 502.2853 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 9.72 3062.6 - 1.83E+06 - - - 1.6119 - 1.816 0.399 - 208.2 1 2 0 0.0016 8 0 0 0 1.49E+08 1.89E+08 - - - 3.7869 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.14271.14271.2 0.000303 14-Aug K.VITMFVQR.Q "sp|P13010|XRCC5_HUMAN,tr|C9JZ81|C9JZ81_HUMAN,tr|H7C0H9|H7C0H9_HUMAN" 3 992.5477 0.8 47907 14271 2 992.549487 497.2811 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 9.72 3062.8 - 1.47E+06 - - - 1.7783 - 1.912 0.418 - 215.4 1 2 0 0.0018 8 0 0 0 1.50E+08 1.88E+08 - - - 4.0826 0.9877 230117_WJC_METTL3_WT_vs_EV_F06.14278.14278.2 3.64 12-Jul K.LWNGLVK.V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 828.4858 0.96 47909 14278 2 828.485955 415.2502 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 3063.7 - 1.17E+06 - - - 0.2185 - 1.114 0.154 - 89.6 1 2 0 0.0002 7 0 0 0 9.98E+07 1.04E+08 - - - 0.5205 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.14279.14279.2 0.0761 14-Jul K.VLLSALER[166.11].L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 909.5523 2.52 47910 14279 2 909.55349 455.7834 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.97 3063.9 - 498054 - - - 1.3226 - 1.516 0.22 - 109.2 1 2 0 0.0012 8 0 0 0 5.65E+08 2.24E+08 - - - 1.9204 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.14285.14285.2 0.152 12-Jun K.LWNGLVK[136.11].V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 836.5 0.91 47913 14285 2 836.500851 419.2573 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 3064.6 - 1.95E+06 - - - 1.0484 - 1.396 0.254 - 65.6 1 2 0 0.0009 7 0 0 0 9.48E+07 1.04E+08 - - - 1.9738 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.14289.14289.2 0.0101 16-Sep R.VLGVLEVSR.S "sp|Q9H0C8|ILKAP_HUMAN,tr|F8SNU7|F8SNU7_HUMAN,tr|H7C2I8|H7C2I8_HUMAN" 3 970.5811 3.62 47915 14289 2 970.581953 486.2978 Integrin-linked kinase-associated serine\threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1 5.97 3065.2 - 831410 - - - 0.8469 - 1.645 0.303 - 249.4 1 2 0 0.0008 9 0 0 0 5.03E+07 1.39E+07 - - - 2.7187 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.14313.14313.2 0.00279 16-Jul K.LLVLDPAQR.L sp|P50750|CDK9_HUMAN 1 1023.6077 1.88 47923 14313 2 1023.608083 512.8111 Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3 5.84 3068.4 - 520622 - - - 0.3937 - 1.557 0.345 - 143 1 2 0 0.0004 9 0 0 0 4.61E+07 2.45E+07 - - - 2.87 0.9695 230117_WJC_METTL3_WT_vs_EV_F06.14314.14314.2 0.134 14-Jun K.DGETIELR.L "sp|P20062|TCO2_HUMAN,tr|B5MBX2|B5MBX2_HUMAN,tr|F8WE86|F8WE86_HUMAN" 3 931.4611 2.76 47924 14314 2 931.460999 466.7378 Transcobalamin-2 OS=Homo sapiens OX=9606 GN=TCN2 PE=1 SV=3 4.14 3068.6 - 319345 - - - -0.0816 - 1.339 0.04 - 94.1 3 2 0 -0.0001 8 0 0 0 2.52E+07 9.16E+06 - - - 0.0037 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.14322.14322.2 0.184 14-Aug K.VLLSALER.L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 899.544 2.51 47928 14322 2 899.545425 450.7793 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.97 3069.5 - 1.04E+07 - - - 1.5652 - 1.741 0.317 - 218.8 1 2 0 0.0014 8 0 0 0 5.61E+08 2.24E+08 - - - 3.0541 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.14325.14325.2 0.0027 20-Sep K.DAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1160.5561 33.59 47931 14325 2 1160.557774 581.2853 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.92 3069.8 - 208391 - - - 1.4441 - 2.155 0.463 - 213.8 1 2 0 0.0017 11 0 0 0 9.23E+06 2.75E+05 - - - 4.5372 0.9906 230117_WJC_METTL3_WT_vs_EV_F06.14329.14329.2 1.43 12-Jun R.FPLVSVR.N "sp|Q8NFF5|FAD1_HUMAN,tr|Q5T196|Q5T196_HUMAN" 2 816.4858 0.99 47933 14329 2 816.487336 409.2502 FAD synthase OS=Homo sapiens OX=9606 GN=FLAD1 PE=1 SV=1 9.75 3070.3 - 575938 - - - 1.9131 - 1.432 0.053 - 82.1 1 2 0 0.0016 7 0 0 0 2.52E+07 2.55E+07 - - - 0.5697 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.14330.14330.2 0.225 14-Jul K.VLETFLAK.S "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 919.5379 1.48 47934 14330 2 919.538837 460.7762 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 5.97 3070.4 - 1.19E+06 - - - 1.0527 - 1.426 0.232 - 140.6 1 2 0 0.001 8 0 0 0 7.76E+07 5.25E+07 - - - 1.8245 0.9698 230117_WJC_METTL3_WT_vs_EV_F06.14335.14335.2 4.4 12-Jun K.EIMLGLK.R "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 802.4623 1.58 47937 14335 2 802.462594 402.2384 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.1 3071 - 1.56E+06 - - - 0.415 - 1.153 0.049 - 108 1 2 0 0.0003 7 0 0 0 8.13E+07 5.16E+07 - - - -0.1461 0.9765 230117_WJC_METTL3_WT_vs_EV_F06.14336.14336.2 2.21 14-Jul K.VLETFLAK[136.11].S "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 927.5521 1.47 47938 14336 2 927.554092 464.7833 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 5.97 3071.1 - 718097 - - - 2.181 - 1.234 0.045 - 105.2 1 2 0 0.002 8 0 0 0 7.72E+07 5.25E+07 - - - 0.0069 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.14337.14337.2 0.00776 16-Oct K.LNSLAIGLR.Q sp|P54886|P5CS_HUMAN 1 955.5815 1.5 47939 14337 2 955.583746 478.798 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3071.3 - 552861 - - - 2.387 - 2.067 0.385 - 281.4 1 2 0 0.0023 9 0 0 0 5.79E+07 3.86E+07 - - - 3.9845 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.14338.14338.2 0.00259 16-Oct K.LNSLAIGLR[166.11].Q sp|P54886|P5CS_HUMAN 1 965.5897 1.52 47940 14338 2 965.592135 483.8021 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3071.4 - 436352 - - - 2.4855 - 2.156 0.339 - 286.4 1 2 0 0.0024 9 0 0 0 5.87E+07 3.87E+07 - - - 3.7667 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.14351.14351.2 0.368 12-Jul K.LSAFAFK.Q sp|O75717|WDHD1_HUMAN 1 782.4327 1.79 47949 14351 2 782.433886 392.2236 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 8.75 3072.9 - 717568 - - - 1.5465 - 1.367 0.251 - 107.2 1 2 0 0.0012 7 0 0 0 3.18E+07 1.78E+07 - - - 1.8851 0.9883 230117_WJC_METTL3_WT_vs_EV_F06.14358.14358.2 0.254 12-Jul K.LSAFAFK[136.11].Q sp|O75717|WDHD1_HUMAN 1 790.4469 1.8 47954 14358 2 790.450712 396.2307 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 8.75 3073.7 - 853921 - - - 4.853 - 1.552 0.182 - 107.1 1 2 0 0.0038 7 0 0 0 3.19E+07 1.78E+07 - - - 1.7768 0.9653 230117_WJC_METTL3_WT_vs_EV_F06.14362.14362.2 0.0615 14-Sep K.NIELAVMR.R "sp|O14818|PSA7_HUMAN,tr|H0Y586|H0Y586_HUMAN" 2 944.5113 2.16 47956 14362 2 944.505447 473.2629 Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1 6 3074.2 - 972354 - - - -6.236 - 1.84 0.319 - 252.7 1 2 0 -0.0059 8 0 0 0 4.23E+07 1.96E+07 - - - 3.2343 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.14371.14371.2 0.000217 28-Sep R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 0.15 47963 14371 2 1410.787706 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3075.3 - 128311 - - - 3.2804 - 1.736 0.317 - 159.3 1 2 0 0.0046 15 0 0 0 9.59E+06 6.56E+07 - - - 2.737 0.9915 230117_WJC_METTL3_WT_vs_EV_F06.14380.14380.2 0.269 12-Jun R.FLDPEFR.E sp|Q5VUA4|ZN318_HUMAN 1 922.4549 1.59 47968 14380 2 922.456801 462.2347 Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2 4.37 3076.4 - 1.97E+06 - - - 2.0955 - 1.116 0.175 - 132.2 1 2 0 0.0019 7 0 0 0 5.10E+07 3.20E+07 - - - 0.6807 1 230117_WJC_METTL3_WT_vs_EV_F06.14396.14396.2 8.45E-06 18-Nov R.IATANMLGIR.K sp|Q9NX20|RM16_HUMAN 1 1058.5907 1.04 47977 14396 2 1058.596064 530.3026 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3078.5 - 369976 - - - 5.1143 - 2.587 0.502 - 360.8 1 2 0 0.0054 10 0 0 0 6.02E+07 5.76E+07 - - - 5.4002 0.9896 230117_WJC_METTL3_WT_vs_EV_F06.14400.14400.2 4.01 12-Jul R.VLGLLER.S "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 798.4963 1.45 47978 14400 2 798.498409 400.2554 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 5.97 3079.1 - 1.74E+06 - - - 2.5924 - 1.403 0.08 - 155.9 1 2 0 0.0021 7 0 0 0 6.56E+07 4.54E+07 - - - 0.7041 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.14401.14401.2 0.00188 26-Sep K.VPQVSTPTLVEVSR.N "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1510.8355 999 47979 14401 2 1510.842245 756.425 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.97 3079.3 - 60941.3 - - - 4.4591 - 1.817 0.412 - 263.5 1 2 0 0.0067 14 0 0 0 2.21E+06 0.00E+00 - - - 3.5805 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.14402.14402.2 0.00474 18-Dec R.IATANMLGIR[166.11].K sp|Q9NX20|RM16_HUMAN 1 1068.5989 1.11 47980 14402 2 1068.602015 535.3067 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3079.4 - 457930 - - - 2.8963 - 1.92 0.387 - 465.7 1 2 0 0.0031 10 0 0 0 6.02E+07 5.41E+07 - - - 3.7192 0.998 230117_WJC_METTL3_WT_vs_EV_F06.14412.14412.2 0.00745 16-Sep R.ILALDC[160.03]GLK[136.11].Y "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1009.5722 1.06 47986 14412 2 1009.575578 505.7934 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.83 3080.8 - 2.00E+06 - - - 3.3925 - 1.792 0.249 - 195.2 1 2 0 0.0034 9 0 0 0 7.03E+07 6.65E+07 - - - 2.5667 0.9885 230117_WJC_METTL3_WT_vs_EV_F06.14434.14434.2 0.0754 12-Jun R.FWETLDR.Y "sp|Q6P1J9|CDC73_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN" 2 965.4607 1.85 48000 14434 2 965.464199 483.7376 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 4.37 3083.4 - 354355 - - - 3.6439 - 1.26 0.181 - 106.8 1 2 0 0.0035 7 0 0 0 5.26E+07 2.85E+07 - - - 1.1091 0.948 230117_WJC_METTL3_WT_vs_EV_F06.14435.14435.2 1.02 18-May R.SLVVPAYAYR.K sp|Q9Y3R4|NEUR2_HUMAN 1 1137.6182 16.61 48001 14435 2 1137.622637 569.8164 Sialidase-2 OS=Homo sapiens OX=9606 GN=NEU2 PE=1 SV=2 8.31 3083.5 - 161457 - - - 3.8607 - 1.231 0.096 - 57.2 3 2 0 0.0044 10 0 0 0 3.58E+06 2.16E+05 - - - 0.1157 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.14436.14436.2 0.404 22-Oct K.SPILVATAVAAR[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1177.7058 1.12 48002 14436 2 1177.706817 589.8602 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3083.7 - 115901 - - - 0.8398 - 1.957 0.179 - 243.3 1 2 0 0.001 12 0 0 0 7.45E+08 6.64E+08 - - - 2.1294 0.9958 230117_WJC_METTL3_WT_vs_EV_F06.14440.14440.2 0.132 14-Jun K.VPGIFISR[166.11].M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 897.5312 0.04 48004 14440 2 897.534253 449.7729 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3084.2 - 1.22E+06 - - - 3.4483 - 1.419 0.236 - 99.8 1 2 0 0.0031 8 0 0 0 2.09E+07 5.04E+08 - - - 1.8386 0.9802 230117_WJC_METTL3_WT_vs_EV_F06.14442.14442.2 0.232 14-May K.LLEPALSQ.- sp|Q05932|FOLC_HUMAN 1 869.4858 - 48006 14442 2 869.487975 435.7502 "Folylpolyglutamate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=FPGS PE=1 SV=3" 4 3084.4 - 531360 - - - 2.4624 - 1.053 0.155 - 54 2 2 0 0.0021 8 0 0 0 - - - - - 0.2064 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.14444.14444.2 0.00109 18-Jul K.LFPGSPAIYK.L "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|F8W705|F8W705_HUMAN,tr|C9JF75|C9JF75_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|C9J6W1|C9J6W1_HUMAN,tr|H0YBN8|H0YBN8_HUMAN,tr|C9J1W9|C9J1W9_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 17 1091.6015 1.74 48007 14444 2 1091.604367 546.808 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 8.59 3084.6 - 377712 - - - 2.5971 - 1.446 0.384 - 131.5 1 2 0 0.0028 10 0 0 0 2.27E+07 1.31E+07 - - - 2.9058 0.998 230117_WJC_METTL3_WT_vs_EV_F06.14446.14446.2 0.229 12-Jul K.GADVWFK.E sp|P05109|S10A8_HUMAN 1 821.4072 8.87 48008 14446 2 821.408694 411.7109 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 5.84 3084.8 - 833555 - - - 1.8322 - 1.41 0.222 - 186.3 1 2 0 0.0015 7 0 0 0 2.95E+07 3.32E+06 - - - 1.7689 0.9958 230117_WJC_METTL3_WT_vs_EV_F06.14448.14448.2 0.461 12-May K.RIYGGFK[136.11].S sp|Q14520|HABP2_HUMAN 1 847.4796 - 48010 14448 2 847.481198 424.7471 Hyaluronan-binding protein 2 OS=Homo sapiens OX=9606 GN=HABP2 PE=1 SV=1 9.99 3085 - 1.39E+06 - - - 1.9175 - 1.341 0.191 - 72.7 3 2 0 0.0016 7 0 0 0 - - - - - 1.1678 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.14449.14449.2 0.0355 14-Jun K.LITEDFVR.Q sp|Q96MG7|NSE3_HUMAN 1 991.5338 5.77 48011 14449 2 991.537255 496.7742 Non-structural maintenance of chromosomes element 3 homolog OS=Homo sapiens OX=9606 GN=NSMCE3 PE=1 SV=1 4.37 3085.1 - 608681 - - - 3.4381 - 1.332 0.318 - 82.6 1 2 0 0.0034 8 0 0 0 1.97E+07 3.41E+06 - - - 2.2533 0.9834 230117_WJC_METTL3_WT_vs_EV_F06.14450.14450.2 0.00803 16-Aug R.FLAEEGFYK[136.11].F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1110.5477 1.25 48012 14450 2 1110.556512 556.2811 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3085.3 - 135719 - - - 7.924 - 1.624 0.418 - 146.2 1 2 0 0.0088 9 0 0 0 1.30E+08 1.04E+08 - - - 3.5284 0.9952 230117_WJC_METTL3_WT_vs_EV_F06.14454.14454.2 0.0132 14-Aug K.VPGIFISR.M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 887.5229 0.38 48014 14454 2 887.524505 444.7687 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3085.8 - 2.86E+06 - - - 1.8219 - 1.626 0.073 - 230.8 1 2 0 0.0016 8 0 0 0 1.14E+08 3.02E+08 - - - 1.0458 0.8736 230117_WJC_METTL3_WT_vs_EV_F06.14455.14455.2 0.00544 20-Oct C.GGAAAVLGAFR[166.11].A sp|Q8NDH3|PEPL1_HUMAN 1 998.5537 0.3 48015 14455 2 998.552224 500.2841 Probable aminopeptidase NPEPL1 OS=Homo sapiens OX=9606 GN=NPEPL1 PE=1 SV=3 9.75 3085.9 - 1.55E+06 - - - -1.4621 - 2.146 0.287 - 369.1 1 1 0 -0.0015 11 0 0 0 1.70E+07 5.73E+07 - - - 3.2261 0.9962 230117_WJC_METTL3_WT_vs_EV_F06.14456.14456.2 0.0251 16-Aug R.VLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 969.5859 1.44 48016 14456 2 969.590504 485.8002 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3086.1 - 1.17E+06 - - - 4.767 - 1.826 0.289 - 173.8 1 2 0 0.0046 9 0 0 0 9.19E+08 6.39E+08 - - - 2.9161 0.9953 230117_WJC_METTL3_WT_vs_EV_F06.14458.14458.2 0.00206 16-Aug R.FLAEEGFYK.F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1102.5335 1.24 48018 14458 2 1102.539182 552.274 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3086.3 - 413417 - - - 5.1427 - 1.471 0.378 - 150.9 1 2 0 0.0057 9 0 0 0 1.30E+08 1.04E+08 - - - 2.9477 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.14462.14462.2 0.00353 16-Oct K.TLAIELAPR[166.11].N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 992.5894 1.04 48020 14462 2 992.593146 497.302 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3086.8 - 389706 - - - 3.773 - 1.676 0.368 - 295.6 1 2 0 0.0037 9 0 0 0 1.89E+09 1.81E+09 - - - 3.2519 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.14463.14463.2 0.381 12-Sep R.VVEFLVK.H sp|P42773|CDN2C_HUMAN 1 832.5058 4.23 48021 14463 2 832.507391 417.2602 Cyclin-dependent kinase 4 inhibitor C OS=Homo sapiens OX=9606 GN=CDKN2C PE=1 SV=1 5.97 3086.9 - 1.30E+06 - - - 1.8618 - 1.317 0.262 - 196.9 1 2 0 0.0016 7 0 0 0 9.18E+07 2.17E+07 - - - 1.8481 0.9917 230117_WJC_METTL3_WT_vs_EV_F06.14464.14464.2 0.6 12-Jul K.LPNLLGR[166.11].A sp|Q9Y512|SAM50_HUMAN 1 791.4893 1.41 48022 14464 2 791.490963 396.7519 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 9.75 3087 - 683789 - - - 2.1099 - 1.248 0.13 - 113.9 1 2 0 0.0017 7 0 0 0 9.19E+07 6.51E+07 - - - 0.7026 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.14470.14470.2 0.0281 18-Aug K.WTLLQEQGTK.T "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1202.6295 10.68 48026 14470 2 1202.632096 602.322 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6 3087.8 - 237521 - - - 2.127 - 1.621 0.111 - 172.4 1 2 0 0.0026 10 0 0 0 3.36E+06 3.15E+05 - - - 1.2084 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.14471.14471.2 0.0464 18-May K.FMQASEDLLK[136.11].E "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 1188.594 4.82 48027 14471 2 1188.597325 595.3043 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.37 3087.9 - 123350 - - - 2.789 - 1.218 0.299 - 56.7 2 2 0 0.0033 10 0 0 0 2.52E+07 5.24E+06 - - - 1.6644 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.14474.14474.2 0.0782 12-Sep R.IAAYLFK.G "sp|Q00610|CLH1_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|J3KRF5|J3KRF5_HUMAN" 5 824.4796 1.15 48028 14474 2 824.481419 413.2471 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.59 3088.3 - 1.51E+06 - - - 2.1747 - 1.921 0.292 - 229.6 1 2 0 0.0018 7 0 0 0 4.22E+08 3.69E+08 - - - 3.2657 0.9471 230117_WJC_METTL3_WT_vs_EV_F06.14477.14477.2 1.84 20-Jun M.VPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1175.7278 3.11 48031 14477 2 1175.728507 588.8712 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.72 3088.7 - 124259 - - - 0.6056 - 1.132 0.009 - 73.6 1 2 0 0.0007 11 0 0 0 2.43E+07 7.82E+06 - - - -0.5573 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.14482.14482.2 0.0135 20-Jul K.LIPGPLSPVAR[166.11].G sp|P48634|PRC2A_HUMAN 1 1128.6894 1.22 48034 14482 2 1128.69172 565.352 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3089.3 - 280206 - - - 2.0121 - 1.528 0.342 - 131.6 1 2 0 0.0023 11 0 0 0 6.98E+08 5.75E+08 - - - 2.7132 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.14483.14483.2 0.000719 14-Aug K.QFFVAVER[166.11].E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1004.5319 1 48035 14483 2 1004.533248 503.2732 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 6 3089.4 - 722447 - - - 1.3559 - 1.611 0.222 - 261.5 1 2 0 0.0014 8 0 0 0 7.59E+07 7.56E+07 - - - 2.1184 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.14493.14493.2 0.0678 16-Aug K.TLAIELAPR.N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 982.5811 1.04 48041 14493 2 982.58273 492.2978 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3090.7 - 4.68E+06 - - - 1.6273 - 1.665 0.269 - 237.1 1 2 0 0.0016 9 0 0 0 1.89E+09 1.81E+09 - - - 2.5023 0.8559 230117_WJC_METTL3_WT_vs_EV_F06.14496.14496.2 3.91 12-Jun K.VWDVIGR[166.11].S "sp|O14618|CCS_HUMAN,tr|J3KNF4|J3KNF4_HUMAN,tr|E9PP76|E9PP76_HUMAN" 3 853.4686 3.94 48044 14496 2 853.465709 427.7416 Copper chaperone for superoxide dismutase OS=Homo sapiens OX=9606 GN=CCS PE=1 SV=1 5.81 3091.1 - 204419 - - - -3.337 - 1.2 0.085 - 77.1 1 2 0 -0.0028 7 0 0 0 4.52E+07 1.15E+07 - - - 0.2456 0.9456 230117_WJC_METTL3_WT_vs_EV_F06.14501.14501.2 1.06 16-May K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 2.89 48045 14501 2 1014.537361 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3091.9 - 419802 - - - 2.7461 - 1.155 0.095 - 37.1 15 2 0 0.0028 9 0 0 0 3.08E+07 1.07E+07 - - - -0.3667 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.14511.14511.2 6.89E-05 20-Sep K.LIPGPLSPVAR.G sp|P48634|PRC2A_HUMAN 1 1118.6812 1.22 48051 14511 2 1118.682418 560.3479 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3093 - 1.63E+06 - - - 1.1076 - 1.836 0.426 - 317.9 1 2 0 0.0012 11 0 0 0 6.98E+08 5.75E+08 - - - 3.8307 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.14514.14514.2 0.0345 20-Jun K.ILATTPSAVFR[166.11].V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1184.6793 1.97 48054 14514 2 1184.679863 593.3469 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3093.4 - 150874 - - - 0.493 - 1.32 0.221 - 82.1 1 2 0 0.0006 11 0 0 0 8.65E+07 4.40E+07 - - - 1.4242 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.14522.14522.2 0.26 14-Aug R.ELVITIAR.E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 913.5597 1.23 48058 14522 2 913.560709 457.7871 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3094.4 - 1.53E+06 - - - 1.1406 - 1.746 0.215 - 310.6 1 2 0 0.001 8 0 0 0 2.82E+08 2.28E+08 - - - 2.3095 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.14524.14524.2 0.0269 14-Jul K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 0.86 48060 14524 2 895.480942 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3094.6 - 680715 - - - 0.6566 - 1.27 0.358 - 134.1 1 2 0 0.0006 8 0 0 0 6.94E+07 8.11E+07 - - - 2.4059 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.14525.14525.2 0.058 20-Oct K.ILATTPSAVFR.V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1174.671 1.97 48061 14525 2 1174.670541 588.3428 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3094.7 - 491734 - - - -0.3984 - 1.674 0.293 - 273.4 1 2 0 -0.0005 11 0 0 0 8.65E+07 4.40E+07 - - - 2.5987 0.998 230117_WJC_METTL3_WT_vs_EV_F06.14529.14529.2 0.103 14-Jul R.ELVITIAR[166.11].E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 923.5679 1.23 48063 14529 2 923.568205 462.7912 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3095.3 - 4.11E+06 - - - 0.2902 - 1.523 0.221 - 244.8 1 2 0 0.0003 8 0 0 0 2.82E+08 2.28E+08 - - - 1.942 0.9927 230117_WJC_METTL3_WT_vs_EV_F06.14530.14530.2 0.0235 16-Jul R.IIPEITAMK.A sp|Q02880|TOP2B_HUMAN 1 1014.5784 1.73 48064 14530 2 1014.578805 508.2965 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 6 3095.4 - 601322 - - - 0.4445 - 1.341 0.127 - 96.3 1 2 0 0.0005 9 0 0 0 1.41E+07 8.19E+06 - - - 0.8277 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.14538.14538.2 0.239 14-Jul R.GLVGEIIK.R "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 827.5117 1 48068 14538 2 827.51186 414.7631 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6 3096.3 - 2.70E+07 - - - 0.2489 - 1.458 0.231 - 161.5 1 2 0 0.0002 8 0 0 0 6.39E+09 6.39E+09 - - - 1.8843 0.9914 230117_WJC_METTL3_WT_vs_EV_F06.14539.14539.2 0.915 14-Aug R.LLPLDFGR[166.11].Y sp|Q9UP52|TFR2_HUMAN 1 939.5417 0 48069 14539 2 939.543545 470.7781 Transferrin receptor protein 2 OS=Homo sapiens OX=9606 GN=TFR2 PE=1 SV=1 5.84 3096.4 - 441856 - - - 1.9403 - 1.383 0.084 - 116 1 2 0 0.0018 8 0 0 0 8.58E+04 2.05E+07 - - - 0.6388 0.9581 230117_WJC_METTL3_WT_vs_EV_F06.14549.14549.2 0.416 12-Jul K.ELLPEIR.E "sp|P49321|NASP_HUMAN,tr|H0YDS9|H0YDS9_HUMAN,tr|Q5T624|Q5T624_HUMAN,tr|H0YF33|H0YF33_HUMAN,tr|E9PRH9|E9PRH9_HUMAN" 5 868.5018 3.2 48074 14549 2 868.501061 435.2582 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 4.53 3097.6 - 1.13E+06 - - - -0.8716 - 1.227 0.056 - 193.6 1 2 0 -0.0008 7 0 0 0 9.64E+07 3.01E+07 - - - 0.1026 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.14554.14554.2 0.00137 18-Aug K.IMLVEPPVAK.V sp|P18583|SON_HUMAN 1 1095.6362 1.41 48077 14554 2 1095.63655 548.8254 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3098.3 - 1.19E+06 - - - 0.3167 - 1.948 0.325 - 192.3 1 2 0 0.0003 10 0 0 0 6.51E+07 4.61E+07 - - - 3.3026 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.14557.14557.2 0.0368 16-Jul R.VYSYALALK.H "sp|Q9UKK9|NUDT5_HUMAN,tr|A6NFX8|A6NFX8_HUMAN" 2 1026.575 3.07 48079 14557 2 1026.577183 514.2948 ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1 8.47 3098.6 - 1.31E+06 - - - 2.143 - 1.268 0.25 - 121.6 1 2 0 0.0022 9 0 0 0 5.96E+07 1.94E+07 - - - 1.5737 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.14559.14559.2 0.0776 18-Oct K.AIITALGVER.R sp|Q92616|GCN1_HUMAN 1 1041.6182 1.99 48080 14559 2 1041.61833 521.8164 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 6.05 3098.8 - 1.31E+06 - - - 0.0816 - 2.178 0.236 - 333.3 1 2 0 0.0001 10 0 0 0 9.09E+07 4.56E+07 - - - 2.9568 1 230117_WJC_METTL3_WT_vs_EV_F06.14575.14575.2 1.91E-07 16-Nov R.GSPLLIGVR.S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 910.56 1.64 48087 14575 2 910.560494 456.2873 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3100.8 - 6.93E+06 - - - 0.5403 - 2.179 0.582 - 520.2 1 2 0 0.0005 9 0 0 0 2.83E+08 1.73E+08 - - - 5.5928 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.14576.14576.2 5.18E-05 16-Nov R.GSPLLIGVR[166.11].S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 920.5683 1.63 48088 14576 2 920.568473 461.2914 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3100.9 - 4.46E+06 - - - 0.2183 - 2.268 0.399 - 543.8 1 2 0 0.0002 9 0 0 0 2.82E+08 1.73E+08 - - - 4.3571 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.14585.14585.2 0.0387 16-Sep K.FVGNIYTLK[136.11].C "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1061.6001 2.03 48093 14585 2 1061.598698 531.8073 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3102.1 - 695741 - - - -1.3037 - 1.502 0.381 - 191.5 1 2 0 -0.0014 9 0 0 0 1.48E+08 7.31E+07 - - - 3.0315 0.8693 230117_WJC_METTL3_WT_vs_EV_F06.14589.14589.2 4.6 16-Jul K.FVGNIYTLK.C "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1053.5859 2.03 48094 14589 2 1053.584583 527.8002 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3102.6 - 1.67E+06 - - - -1.2329 - 1.032 0.045 - 109.7 1 2 0 -0.0013 9 0 0 0 1.48E+08 7.31E+07 - - - -0.5359 0.9964 230117_WJC_METTL3_WT_vs_EV_F06.14591.14591.2 4.93 12-Jul R.ELLEIVK.K sp|P31153|METK2_HUMAN 1 842.5113 1.25 48096 14591 2 842.511711 422.2629 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 4.53 3102.9 - 1.72E+06 - - - 0.4641 - 1.613 0.111 - 173.1 1 2 0 0.0004 7 0 0 0 8.81E+07 7.03E+07 - - - 1.3756 0.9911 230117_WJC_METTL3_WT_vs_EV_F06.14595.14595.2 0.459 12-Aug R.TLDTFLR.S sp|Q96SK2|TM209_HUMAN 1 864.4705 1.44 48098 14595 2 864.469437 433.2425 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 5.5 3103.3 - 3.01E+06 - - - -1.2505 - 1.401 0.179 - 178.4 1 2 0 -0.0011 7 0 0 0 1.01E+08 7.05E+07 - - - 1.4311 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.14596.14596.2 0.0383 16-Jul R.EVIAGPLLR.N "sp|Q6DKJ4|NXN_HUMAN,tr|I3L4V6|I3L4V6_HUMAN" 2 966.5862 0.14 48099 14596 2 966.585617 484.3004 Nucleoredoxin OS=Homo sapiens OX=9606 GN=NXN PE=1 SV=2 6.1 3103.4 - 1.38E+06 - - - -0.6197 - 1.35 0.336 - 94.7 1 2 0 -0.0006 9 0 0 0 3.34E+07 2.43E+08 - - - 2.3907 0.9861 230117_WJC_METTL3_WT_vs_EV_F06.14599.14599.2 0.979 14-Sep R.YADLLLEK[136.11].E sp|Q99459|CDC5L_HUMAN 1 971.5419 1.17 48100 14599 2 971.540747 486.7782 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3103.8 - 1.26E+06 - - - -1.1847 - 1.494 0.125 - 159.6 2 2 0 -0.0012 8 0 0 0 3.85E+08 3.29E+08 - - - 1.0402 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.14600.14600.2 0.292 14-Sep R.YADLLLEK.E sp|Q99459|CDC5L_HUMAN 1 963.5277 1.17 48101 14600 2 963.528474 482.7711 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3103.9 - 1.33E+06 - - - 0.8054 - 1.514 0.264 - 195.8 1 2 0 0.0008 8 0 0 0 3.86E+08 3.30E+08 - - - 2.2415 0.9789 230117_WJC_METTL3_WT_vs_EV_F06.14601.14601.2 0.594 12-Aug R.TLDTFLR[166.11].S sp|Q96SK2|TM209_HUMAN 1 874.4788 1.66 48102 14601 2 874.478779 438.2467 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 5.5 3104 - 1.72E+06 - - - -0.0103 - 1.206 0.08 - 206.3 1 2 0 0 7 0 0 0 9.97E+07 6.00E+07 - - - 0.2254 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.14607.14607.2 0.000191 16-Nov R.MGPNIYELR.T "sp|Q9BPW8|NIPS1_HUMAN,tr|C9JDV8|C9JDV8_HUMAN,tr|H7C2U6|H7C2U6_HUMAN" 3 1091.5434 1.57 48105 14607 2 1091.541887 546.779 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.75 3104.7 - 535708 - - - -1.354 - 2.081 0.364 - 523.8 1 2 0 -0.0015 9 0 0 0 6.65E+07 4.23E+07 - - - 3.8492 0.998 230117_WJC_METTL3_WT_vs_EV_F06.14611.14611.2 0.116 14-Jun R.EFADFEYR[166.11].K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1085.4693 1.17 48109 14611 2 1085.469644 543.7419 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3105.2 - 463092 - - - 0.2755 - 1.301 0.289 - 161 1 2 0 0.0003 8 0 0 0 1.96E+07 1.68E+07 - - - 1.9691 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.14615.14615.2 5.85E-05 14-Jun R.EFADFEYR.K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1075.4611 1.17 48111 14615 2 1075.457797 538.7378 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3105.8 - 507628 - - - -3.048 - 1.568 0.517 - 160.8 1 2 0 -0.0033 8 0 0 0 1.96E+07 1.68E+07 - - - 4.2151 0.9877 230117_WJC_METTL3_WT_vs_EV_F06.14623.14623.2 0.733 14-May R.GLVGEIIK[136.11].R "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 835.5259 1 48114 14623 2 835.525845 418.7702 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6 3106.9 - 4.16E+07 - - - -0.0108 - 1.33 0.113 - 73.6 2 2 0 0 8 0 0 0 6.38E+09 6.39E+09 - - - 0.6012 0.9876 230117_WJC_METTL3_WT_vs_EV_F06.14624.14624.2 0.0881 16-Aug K.LVTEPLVLK[136.11].S sp|O43896|KIF1C_HUMAN 1 1018.6518 0.05 48115 14624 2 1018.658043 510.3332 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 6 3107 - 595570 - - - 6.1454 - 1.72 0.27 - 159.6 1 2 0 0.0063 9 0 0 0 2.42E+06 4.75E+07 - - - 2.6022 0.9346 230117_WJC_METTL3_WT_vs_EV_F06.14629.14629.3 2.86 Aug-52 R.RGNYPGPSSPVVVR[166.11].L "sp|B2RTY4|MYO9A_HUMAN,tr|H3BV44|H3BV44_HUMAN,tr|H3BU05|H3BU05_HUMAN,tr|H3BP49|H3BP49_HUMAN,tr|H3BRD5|H3BRD5_HUMAN" 5 1493.7978 - 48118 14629 3 1493.796644 498.9399 Unconventional myosin-IXa OS=Homo sapiens OX=9606 GN=MYO9A PE=1 SV=2 10.84 3107.6 - 594483 - - - -0.7946 - 1.342 0.164 - 47.5 6 2 0 -0.0012 14 0 0 0 - - - - - 0.7897 0.9332 230117_WJC_METTL3_WT_vs_EV_F06.14630.14630.2 1.96 14-Jun K.FYGELALK.K "sp|P78527|PRKDC_HUMAN,tr|F5GX40|F5GX40_HUMAN" 2 939.5066 1.09 48119 14630 2 939.506166 470.7606 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 3107.7 - 325360 - - - -0.4289 - 1.082 0.063 - 90.6 2 2 0 -0.0004 8 0 0 0 5.55E+07 5.09E+07 - - - -0.3906 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.14652.14652.2 0.0052 18-Nov R.VVVDALSGLK.G "sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|F8WCN3|F8WCN3_HUMAN" 3 999.5964 1.84 48131 14652 2 999.59652 500.8055 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 5.81 3110.7 - 660356 - - - 0.073 - 1.945 0.369 - 313.8 1 2 0 0.0001 10 0 0 0 9.10E+07 4.96E+07 - - - 3.6234 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.14660.14660.2 0.0147 14-Jun K.LLESDYFR.Y "sp|Q96HE7|ERO1A_HUMAN,tr|G3V503|G3V503_HUMAN,tr|G3V3E6|G3V3E6_HUMAN" 3 1041.5131 1.75 48137 14660 2 1041.511285 521.7638 ERO1-like protein alpha OS=Homo sapiens OX=9606 GN=ERO1A PE=1 SV=2 4.37 3111.6 - 379015 - - - -1.7532 - 1.386 0.382 - 94.6 1 2 0 -0.0018 8 0 0 0 1.62E+07 9.26E+06 - - - 2.8464 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.14666.14666.2 0.00054 12-Aug R.TMLLLSR.S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 832.4841 1.96 48141 14666 2 832.484818 417.2493 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.41 3112.2 - 2.27E+06 - - - 0.9117 - 1.607 0.271 - 256.5 1 2 0 0.0008 7 0 0 0 1.20E+08 6.14E+07 - - - 2.5454 0.8816 230117_WJC_METTL3_WT_vs_EV_F06.14670.14670.2 0.27 14-Jun Y.FLLTQAVR.T sp|O43242|PSMD3_HUMAN 1 946.56 3.86 48143 14670 2 946.561148 474.2873 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 9.75 3112.7 - 4.43E+06 - - - 1.2107 - 1.446 0.233 - 114.4 1 1 0 0.0011 8 0 0 0 4.08E+08 1.06E+08 - - - 1.8739 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.14671.14671.2 0.0203 14-Jul K.IIYIAPMR.S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 975.5576 0.9 48144 14671 2 975.558571 488.7861 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 3112.7 - 3.17E+06 - - - 1.0374 - 1.433 0.332 - 157.1 1 2 0 0.001 8 0 0 0 1.33E+08 1.49E+08 - - - 2.5779 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.14676.14676.2 0.00116 18-Oct R.VVVDALSGLK[136.11].G "sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|F8WCN3|F8WCN3_HUMAN" 3 1007.6106 1.84 48147 14676 2 1007.613561 504.8126 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 5.81 3113.3 - 1.30E+06 - - - 2.892 - 2.125 0.42 - 296.8 1 2 0 0.0029 10 0 0 0 9.11E+07 4.96E+07 - - - 4.2462 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.14684.14684.2 1.15 16-Sep K.LGIIGVVNR.S "sp|O00429|DNM1L_HUMAN,tr|F8VZ52|F8VZ52_HUMAN" 2 939.5866 1.46 48152 14684 2 939.587679 470.8006 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 9.75 3114.2 - 1.19E+06 - - - 1.2005 - 1.748 0.285 - 188 1 2 0 0.0011 9 0 0 0 8.15E+07 5.57E+07 - - - 2.7613 0.9935 230117_WJC_METTL3_WT_vs_EV_F06.14688.14688.2 0.33 12-Jul R.TMLLLSR[166.11].S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 842.4923 2 48154 14688 2 842.491797 422.2534 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.41 3114.7 - 2.08E+06 - - - -0.6315 - 1.335 0.19 - 196.5 1 2 0 -0.0005 7 0 0 0 1.22E+08 6.13E+07 - - - 1.3597 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.14693.14693.2 0.12 18-Aug K.GVAYTLLTPK[136.11].D "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1069.6263 3.25 48157 14693 2 1069.628122 535.8204 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.59 3115.3 - 463367 - - - 1.7062 - 1.216 0.285 - 151.7 1 2 0 0.0018 10 0 0 0 5.10E+07 1.57E+07 - - - 1.6913 0.9917 230117_WJC_METTL3_WT_vs_EV_F06.14701.14701.2 1.15 14-Jun K.YGLKPPTL.- sp|O94826|TOM70_HUMAN 1 887.5117 0.36 48162 14701 2 887.512329 444.7631 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.59 3116.2 - 779074 - - - 0.7606 - 1.126 0.188 - 96.1 2 2 0 0.0007 8 0 0 0 4.37E+07 1.21E+08 - - - 0.6528 0.98 230117_WJC_METTL3_WT_vs_EV_F06.14704.14704.2 2.06 16-May R.VIMSDLQIR[166.11].G "sp|Q9UIF9|BAZ2A_HUMAN,tr|A0A0C4DGI9|A0A0C4DGI9_HUMAN,tr|F8VU39|F8VU39_HUMAN,tr|J3KPG5|J3KPG5_HUMAN" 4 1083.5986 0.96 48164 14704 2 1083.600415 542.8066 Bromodomain adjacent to zinc finger domain protein 2A OS=Homo sapiens OX=9606 GN=BAZ2A PE=1 SV=4 5.81 3116.6 - 72329.3 - - - 1.6888 - 1.052 0.131 - 53.5 2 2 0 0.0018 9 0 0 0 2.57E+06 2.69E+06 - - - 0.0202 0.9884 230117_WJC_METTL3_WT_vs_EV_F06.14708.14708.2 0.188 12-Aug R.VAFVNFR[166.11].R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 861.4736 1.06 48166 14708 2 861.477208 431.7441 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 9.72 3117 - 1.36E+06 - - - 4.1383 - 1.737 0.079 - 268.6 1 2 0 0.0036 7 0 0 0 1.44E+08 1.35E+08 - - - 1.3729 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.14709.14709.2 0.0277 12-Sep K.FDLMYAK.R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 886.4259 3.1 48167 14709 2 886.428016 444.2202 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3117.1 - 1.34E+06 - - - 2.4142 - 1.571 0.331 - 259.1 1 2 0 0.0021 7 0 0 0 9.98E+08 3.22E+08 - - - 2.9164 0.9575 230117_WJC_METTL3_WT_vs_EV_F06.14716.14716.2 1.95 18-May R.LLENMTEVVR.K "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 1202.6329 28.48 48171 14716 2 1202.639131 602.3237 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 3118 - 126198 - - - 5.1736 - 1.262 0.181 - 58.4 2 2 0 0.0062 10 0 0 0 5.58E+06 1.96E+05 - - - 0.891 0.9643 230117_WJC_METTL3_WT_vs_EV_F06.14726.14726.2 7.84 12-Jun K.LVLILNK.S "sp|Q9BVP2|GNL3_HUMAN,sp|Q96RW7|HMCN1_HUMAN" 2 811.5531 0.96 48178 14726 2 811.554108 406.7838 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.75 3119.2 - 1.04E+06 - - - 1.2113 - 1.194 0.003 - 116.4 1 2 0 0.001 7 0 0 0 7.85E+07 8.20E+07 - - - -0.3753 0.9755 230117_WJC_METTL3_WT_vs_EV_F06.14733.14733.2 0.0654 14-Jun K.LTPLLSVR[166.11].E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 907.573 0.9 48183 14733 2 907.573955 454.7938 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3119.9 - 5.20E+06 - - - 1.0269 - 1.235 0.046 - 167.7 2 2 0 0.0009 8 0 0 0 2.77E+08 3.07E+08 - - - -0.1174 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.14737.14737.2 0.000124 12-Aug K.FDLMYAK[136.11].R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 894.4401 3.1 48185 14737 2 894.441056 448.2273 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3120.4 - 4.96E+06 - - - 1.0957 - 1.738 0.266 - 195.5 1 2 0 0.001 7 0 0 0 9.98E+08 3.22E+08 - - - 2.7567 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.14744.14744.2 0.0731 16-Sep K.GFVTADMIR.E sp|Q9UHQ9|NB5R1_HUMAN 1 1008.5063 1.87 48189 14744 2 1008.506863 505.2604 NADH-cytochrome b5 reductase 1 OS=Homo sapiens OX=9606 GN=CYB5R1 PE=1 SV=1 5.84 3121.2 - 552694 - - - 0.6068 - 1.9 0.391 - 252.2 1 2 0 0.0006 9 0 0 0 1.84E+07 9.85E+06 - - - 3.7857 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.14759.14759.2 0.0151 12-Aug R.FC[160.03]DVLLR.V "sp|Q9HBE1|PATZ1_HUMAN,tr|B1ARF3|B1ARF3_HUMAN" 2 921.4742 0.02 48198 14759 2 921.475671 461.7444 "POZ-, AT hook-, and zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=PATZ1 PE=1 SV=1" 5.83 3122.9 - 670404 - - - 1.5714 - 1.435 0.269 - 236.2 1 2 0 0.0014 7 0 0 0 2.21E+07 9.65E+08 - - - 2.1718 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.14769.14769.2 0.00294 16-Nov K.IPFASLASR.L sp|P35573|GDE_HUMAN 1 960.5393 0.63 48206 14769 2 960.541338 481.2769 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3124 - 738740 - - - 2.1571 - 1.716 0.353 - 289.3 1 2 0 0.0021 9 0 0 0 3.74E+07 5.98E+07 - - - 3.2098 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.14774.14774.2 0.0276 18-Nov R.VLLGEGVLTK[136.11].E "sp|Q96S99|PKHF1_HUMAN,sp|Q9H8W4|PKHF2_HUMAN,tr|K7ELB8|K7ELB8_HUMAN,tr|K7EIX0|K7EIX0_HUMAN" 4 1035.6419 0.82 48209 14774 2 1035.642877 518.8282 Pleckstrin homology domain-containing family F member 1 OS=Homo sapiens OX=9606 GN=PLEKHF1 PE=1 SV=3 5.97 3124.6 - 1.38E+06 - - - 0.898 - 2.058 0.454 - 289.6 1 2 0 0.0009 10 0 0 0 4.16E+07 5.07E+07 - - - 4.4085 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.14775.14775.2 0.674 14-Aug R.LYELDGLR.E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 977.5182 3.1 48210 14775 2 977.519366 489.7664 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3124.7 - 426012 - - - 1.1969 - 1.548 0.241 - 188.5 1 2 0 0.0012 8 0 0 0 8.00E+08 2.58E+08 - - - 2.1385 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.14780.14780.2 0.0264 16-Jul K.IPFASLASR[166.11].L sp|P35573|GDE_HUMAN 1 970.5475 1.83 48214 14780 2 970.54981 486.281 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3125.3 - 805158 - - - 2.343 - 1.527 0.264 - 113.2 1 2 0 0.0023 9 0 0 0 3.63E+07 1.99E+07 - - - 2.2148 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.14784.14784.2 0.039 12-Jun R.ELFVMAR.E "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QSA9|J3QSA9_HUMAN" 4 864.4528 5.32 48216 14784 2 864.453326 433.2337 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 6.1 3125.8 - 4.13E+06 - - - 0.6559 - 1.411 0.245 - 183 1 2 0 0.0006 7 0 0 0 2.00E+08 3.76E+07 - - - 1.9413 0.9964 230117_WJC_METTL3_WT_vs_EV_F06.14785.14785.2 0.382 14-Aug R.LYELDGLR[166.11].E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 987.5265 3.09 48217 14785 2 987.529958 494.7705 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3126 - 1.30E+06 - - - 3.5361 - 1.698 0.192 - 191.4 1 2 0 0.0035 8 0 0 0 7.97E+08 2.58E+08 - - - 2.0548 0.9836 230117_WJC_METTL3_WT_vs_EV_F06.14790.14790.2 0.264 12-Jun R.AVTIFIR[166.11].G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 828.5097 4.74 48220 14790 2 828.509577 415.2621 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3126.6 - 6.48E+06 - - - -0.1412 - 1.444 0.051 - 147.8 2 2 0 -0.0001 7 0 0 0 4.87E+09 1.03E+09 - - - 0.4474 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.14792.14792.2 0.0132 14-Sep R.VPTWGPLR[166.11].G "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 3 934.5264 1.13 48221 14792 2 934.526491 468.2705 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.72 3126.8 - 2.76E+06 - - - 0.0899 - 1.577 0.306 - 296.1 1 2 0 0.0001 8 0 0 0 1.58E+08 1.40E+08 - - - 2.6749 0.9931 230117_WJC_METTL3_WT_vs_EV_F06.14794.14794.2 0.00916 14-Jun K.LTPLLSVR.E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 897.5648 0.9 48223 14794 2 897.564341 449.7897 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3127 - 8.75E+06 - - - -0.459 - 1.299 0.19 - 197.2 1 2 0 -0.0004 8 0 0 0 2.77E+08 3.07E+08 - - - 1.2332 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.14803.14803.2 0.0673 16-Aug K.LISYSYMVR[166.11].G sp|P07099|HYEP_HUMAN 1 1140.5877 1 48227 14803 2 1140.585128 571.3011 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 8.59 3128.1 - 939198 - - - -2.2427 - 1.561 0.327 - 163.7 1 2 0 -0.0026 9 0 0 0 2.03E+07 2.04E+07 - - - 2.7438 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.14809.14809.2 0.0117 16-Sep R.VLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 11 1028.5866 13399.39 48232 14809 2 1028.585987 515.3006 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3128.9 - 1.22E+07 - - - -0.6057 - 2.015 0.444 - 316.9 1 2 0 -0.0006 9 0 0 0 2.54E+09 1.89E+05 - - - 4.3471 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.14811.14811.2 0.0406 14-Aug R.VPTWGPLR.G "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 3 924.5181 0.97 48233 14811 2 924.517444 463.2663 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.72 3129.1 - 2.49E+06 - - - -0.7496 - 1.505 0.259 - 263.8 1 2 0 -0.0007 8 0 0 0 1.63E+08 1.69E+08 - - - 2.1867 0.9827 230117_WJC_METTL3_WT_vs_EV_F06.14822.14822.2 0.342 16-Sep K.LLSSLGGFK[136.11].L sp|Q92616|GCN1_HUMAN 1 928.5473 2.43 48238 14822 2 928.545325 465.2809 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.75 3130.6 - 908577 - - - -2.1464 - 1.38 0.186 - 156.4 1 2 0 -0.002 9 0 0 0 1.58E+07 6.51E+06 - - - 1.346 0.999 230117_WJC_METTL3_WT_vs_EV_F06.14835.14835.2 0.0343 18-Sep K.AYAALAALEK[136.11].L sp|Q12906|ILF3_HUMAN 1 1027.5793 0.6 48247 14835 2 1027.579068 514.7969 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.05 3132.1 - 1.29E+06 - - - -0.2715 - 1.498 0.387 - 181.1 1 2 0 -0.0003 10 0 0 0 7.16E+08 1.20E+09 - - - 3.0273 0.9752 230117_WJC_METTL3_WT_vs_EV_F06.14843.14843.2 5.53 12-Aug K.LGFEEFK.Y "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 868.4331 2.66 48248 14843 2 868.432966 435.2238 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 3133.4 - 3.47E+06 - - - -0.1198 - 1.188 0.077 - 162.1 1 2 0 -0.0001 7 0 0 0 3.19E+08 1.20E+08 - - - 0.1555 0.9956 230117_WJC_METTL3_WT_vs_EV_F06.14852.14852.2 0.0168 14-Aug R.DAFVYAIK.N "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 925.4909 0.81 48250 14852 2 925.489874 463.7527 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 5.83 3134.7 - 2.39E+06 - - - -1.1291 - 1.385 0.266 - 263.7 1 2 0 -0.001 8 0 0 0 1.83E+08 2.27E+08 - - - 1.9876 0.9947 230117_WJC_METTL3_WT_vs_EV_F06.14856.14856.2 0.0201 12-Jul K.LGFEEFK[136.11].Y "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 876.4473 2.62 48252 14856 2 876.44649 439.2309 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 3135.1 - 3.13E+06 - - - -0.89 - 1.573 0.162 - 143.5 1 2 0 -0.0008 7 0 0 0 3.20E+08 1.22E+08 - - - 1.6726 0.9439 230117_WJC_METTL3_WT_vs_EV_F06.14858.14858.2 2.5 12-Jun K.YLPDIIK.D sp|O15355|PPM1G_HUMAN 1 860.5008 6.06 48253 14858 2 860.498629 431.2577 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 5.83 3135.4 - 2.77E+06 - - - -2.4707 - 1.039 0.193 - 119.8 1 2 0 -0.0021 7 0 0 0 2.49E+08 4.11E+07 - - - 0.5871 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.14861.14861.2 0.505 18-Oct R.INEILSNALK.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 3 1113.6394 12.38 48255 14861 2 1113.639724 557.827 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3135.7 - 893484 - - - 0.3143 - 2.112 0.251 - 243.8 1 2 0 0.0003 10 0 0 0 1.54E+07 1.25E+06 - - - 2.9817 1 230117_WJC_METTL3_WT_vs_EV_F06.14863.14863.2 4.63E-08 14/22 K.FAQALGLTEAVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1246.6921 0.89 48257 14863 2 1246.692507 624.3533 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3135.9 - 1.53E+06 - - - 0.296 - 2.718 0.418 - 661.1 1 2 0 0.0004 12 0 0 0 2.25E+07 2.54E+07 - - - 4.7591 0.9956 230117_WJC_METTL3_WT_vs_EV_F06.14870.14870.2 0.721 16-Oct R.AFSYYGPLR[166.11].T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1082.5425 0.85 48258 14870 2 1082.538929 542.2785 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3137 - 2.41E+06 - - - -3.2535 - 2.099 0.326 - 401.8 1 2 0 -0.0035 9 0 0 0 3.83E+08 4.54E+08 - - - 3.5928 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.14872.14872.2 0.26 12-Jul K.FLSVLER[166.11].Q sp|P07099|HYEP_HUMAN 1 872.4995 0.94 48259 14872 2 872.501217 437.257 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 6 3137.2 - 1.80E+06 - - - 1.9415 - 1.586 0.218 - 164.4 1 2 0 0.0017 7 0 0 0 1.16E+08 1.23E+08 - - - 2.112 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.14877.14877.2 1.16E-05 16-Oct R.AFSYYGPLR.T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1072.5342 0.85 48261 14877 2 1072.534465 537.2744 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3137.8 - 2.75E+06 - - - 0.2648 - 1.964 0.486 - 379.5 1 2 0 0.0003 9 0 0 0 3.83E+08 4.54E+08 - - - 4.5833 0.9575 230117_WJC_METTL3_WT_vs_EV_F06.14889.14889.2 4.97 12-Aug K.YVLALVK[136.11].K "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 812.5251 1.13 48265 14889 2 812.522036 407.2698 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.59 3139.3 - 2.21E+06 - - - -3.803 - 1.274 0.221 - 202.2 1 2 0 -0.0031 7 0 0 0 9.46E+07 8.40E+07 - - - 1.4396 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.14891.14891.2 0.0105 16-Sep R.ILDSAEFIK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1042.579 0.94 48266 14891 2 1042.579674 522.2968 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3139.5 - 3.46E+06 - - - 0.635 - 1.756 0.323 - 104.9 1 2 0 0.0007 9 0 0 0 1.20E+10 1.28E+10 - - - 3.0554 0.999 230117_WJC_METTL3_WT_vs_EV_F06.14894.14894.2 0.00145 16-Sep R.ILDSAEFIK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1034.5648 0.94 48267 14894 2 1034.56421 518.2897 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3139.9 - 3.26E+06 - - - -0.5819 - 1.631 0.389 - 163.2 1 2 0 -0.0006 9 0 0 0 1.20E+10 1.28E+10 - - - 3.3292 0.996 230117_WJC_METTL3_WT_vs_EV_F06.14895.14895.2 0.0219 12-Jun K.YNIMLVR.L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 907.495 8.12 48268 14895 2 907.493498 454.7548 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3140 - 4.78E+06 - - - -1.6088 - 1.467 0.287 - 163.7 1 2 0 -0.0015 7 0 0 0 3.06E+09 3.78E+08 - - - 2.3746 0.8832 230117_WJC_METTL3_WT_vs_EV_F06.14903.14903.2 0.00148 14-Oct R.PFTLGQLK.E "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 902.5226 0.21 48272 14903 2 902.521312 452.2686 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 9.18 3141 - 1.14E+06 - - - -1.375 - 1.869 0.318 - 301.1 1 1 0 -0.0012 8 0 0 0 4.84E+07 2.26E+08 - - - 3.2755 0.9454 230117_WJC_METTL3_WT_vs_EV_F06.14904.14904.2 11.2 12-Jun R.IFLQDIK.K "sp|P02794|FRIH_HUMAN,tr|E9PRK8|E9PRK8_HUMAN,tr|E9PKY7|E9PKY7_HUMAN,tr|G3V1D1|G3V1D1_HUMAN,tr|E9PPQ4|E9PPQ4_HUMAN,tr|G3V192|G3V192_HUMAN" 6 875.5117 1.49 48273 14904 2 875.51221 438.7631 Ferritin heavy chain OS=Homo sapiens OX=9606 GN=FTH1 PE=1 SV=2 5.84 3141.1 - 2.46E+06 - - - 0.6351 - 1.156 0.025 - 93.6 4 2 0 0.0006 7 0 0 0 9.84E+07 6.61E+07 - - - -0.5841 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.14910.14910.2 0.212 12-Jul K.YNIMLVR[166.11].L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 917.5032 8.12 48276 14910 2 917.505364 459.7589 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3141.9 - 2.26E+06 - - - 2.3281 - 1.571 0.262 - 200.7 1 2 0 0.0021 7 0 0 0 3.06E+09 3.78E+08 - - - 2.4067 0.9398 230117_WJC_METTL3_WT_vs_EV_F06.14918.14918.2 8.59 12-May R.VDDFLR[166.11]R.T "sp|Q96MU7|YTDC1_HUMAN,tr|J3QR07|J3QR07_HUMAN" 2 929.4958 - 48277 14918 2 929.496937 465.7552 YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3 5.93 3143.1 - 2.94E+06 - - - 1.1856 - 1.091 0.014 - 94.7 2 2 0 0.0011 7 0 0 0 - - - - - -0.7144 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.14941.14941.2 0.0455 20-Dec K.LVLLGESAVGK[136.11].S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1092.6634 1.39 48286 14941 2 1092.662671 547.339 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3146 - 2.57E+06 - - - -0.6772 - 2.227 0.34 - 361.3 1 2 0 -0.0007 11 0 0 0 1.87E+08 1.35E+08 - - - 3.718 0.9943 230117_WJC_METTL3_WT_vs_EV_F06.14946.14946.2 1.76 12-Jul R.LNLYELK.E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 891.5066 2.12 48289 14946 2 891.505989 446.7606 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3146.6 - 5.64E+06 - - - -0.6506 - 1.452 0.17 - 173.9 1 2 0 -0.0006 7 0 0 0 3.00E+08 1.41E+08 - - - 1.4781 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.14950.14950.2 0.00605 20-Sep K.LVLLGESAVGK.S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1084.6492 1.39 48291 14950 2 1084.647672 543.3319 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3147.1 - 4.71E+06 - - - -1.4189 - 2.015 0.25 - 188.3 1 2 0 -0.0015 11 0 0 0 1.87E+08 1.35E+08 - - - 2.7824 0.9899 230117_WJC_METTL3_WT_vs_EV_F06.14954.14954.2 0.452 12-Jul R.LNLYELK[136.11].E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 899.5208 2.12 48293 14954 2 899.51915 450.7677 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3147.7 - 2.39E+06 - - - -1.7998 - 1.561 0.158 - 163.4 1 2 0 -0.0016 7 0 0 0 3.00E+08 1.41E+08 - - - 1.6185 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.14957.14957.2 0.00388 16-Aug K.YLPELMAEK[136.11].D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1100.5667 1.15 48294 14957 2 1100.567504 551.2906 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3148 - 2.84E+06 - - - 0.7005 - 1.531 0.325 - 206.7 1 2 0 0.0008 9 0 0 0 1.99E+08 1.74E+08 - - - 2.6734 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.14958.14958.2 0.00505 18-Aug R.FLIC[160.03]TDVAAR[166.11].G "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 1174.6044 1.78 48295 14958 2 1174.602899 588.3095 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.83 3148.2 - 1.63E+06 - - - -1.277 - 1.517 0.34 - 173.5 1 2 0 -0.0015 10 0 0 0 5.43E+07 3.06E+07 - - - 2.715 0.9948 230117_WJC_METTL3_WT_vs_EV_F06.14961.14961.2 0.00444 16-Sep K.YLPELMAEK.D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1092.5525 1.14 48296 14961 2 1092.549097 547.2835 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3148.6 - 3.63E+06 - - - -3.1449 - 1.388 0.439 - 268.1 1 2 0 -0.0034 9 0 0 0 2.00E+08 1.76E+08 - - - 3.2309 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.14969.14969.2 0.106 12-Jun K.FADFMVK.D "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 14 856.4153 1.84 48299 14969 2 856.415791 429.2149 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 5.84 3149.6 - 1.24E+06 - - - 0.5605 - 1.23 0.282 - 84.2 1 2 0 0.0005 7 0 0 0 6.47E+07 3.52E+07 - - - 1.7796 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.14989.14989.2 0.0181 13/20 R.MGAGMGFGLER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1134.519 1.91 48306 14989 2 1134.516728 568.2668 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 3152.3 - 954396 - - - -1.9629 - 2.067 0.402 - 368.3 1 2 0 -0.0022 11 0 0 0 8.19E+07 4.29E+07 - - - 3.9737 0.9047 230117_WJC_METTL3_WT_vs_EV_F06.14991.14991.2 0.461 14-Sep R.PIVTVWER[166.11].E "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EQR8|K7EQR8_HUMAN" 3 1008.5632 2.94 48307 14991 2 1008.563261 505.2889 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 6.43 3152.5 - 1.34E+06 - - - 0.0744 - 1.712 0.243 - 328.3 1 1 0 0.0001 8 0 0 0 2.18E+08 7.41E+07 - - - 2.4573 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.15011.15011.2 0.0215 14-Aug R.VMLYPSRI.- sp|P18077|RL35A_HUMAN 1 977.5368 0.81 48320 15011 2 977.537279 489.7757 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.72 3155 - 2.27E+06 - - - 0.4665 - 1.431 0.273 - 303.6 1 2 0 0.0005 8 0 0 0 1.44E+08 1.77E+08 - - - 2.1381 0.9671 230117_WJC_METTL3_WT_vs_EV_F06.15013.15013.2 3.31 12-Jun K.WDPVVLK.N sp|Q9BVJ6|UT14A_HUMAN 1 855.4854 1.19 48321 15013 2 855.486089 428.75 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 5.84 3155.2 - 3.28E+06 - - - 0.7586 - 1.051 0.071 - 143.5 1 2 0 0.0006 7 0 0 0 1.09E+08 9.21E+07 - - - -0.2772 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.15023.15023.2 0.0203 14-Jun R.VMLYPSR[166.11]I.- sp|P18077|RL35A_HUMAN 1 987.5451 0.79 48328 15023 2 987.546898 494.7798 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.72 3156.3 - 2.20E+06 - - - 1.8278 - 1.505 0.331 - 147.2 1 2 0 0.0018 8 0 0 0 1.39E+08 1.77E+08 - - - 2.7181 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15024.15024.2 0.00179 18-Nov R.ILALEADMTK.W "sp|Q4VCS5|AMOT_HUMAN,sp|Q9Y2J4|AMOL2_HUMAN,sp|Q8IY63|AMOL1_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 5 1103.5896 3 48329 15024 2 1103.59275 552.8021 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.37 3156.4 - 1.10E+06 - - - 2.8117 - 2.059 0.364 - 288.5 1 2 0 0.0031 10 0 0 0 3.95E+07 1.31E+07 - - - 3.7445 0.9952 230117_WJC_METTL3_WT_vs_EV_F06.15030.15030.2 0.798 14-Jul K.LIYLVPEK.Q "sp|Q9NZM3|ITSN2_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN,tr|E7EPJ2|E7EPJ2_HUMAN" 3 973.5848 4.2 48333 15030 2 973.586082 487.7997 Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3 6 3157.1 - 1.07E+06 - - - 1.2973 - 1.192 0.194 - 140.9 1 2 0 0.0013 8 0 0 0 5.24E+07 1.25E+07 - - - 1.0032 0.9462 230117_WJC_METTL3_WT_vs_EV_F06.15032.15032.2 2.7 12-Jun R.DLGAYLR.Q "sp|Q9BRT2|UQCC2_HUMAN,tr|Q5TAQ0|Q5TAQ0_HUMAN,tr|V5IRT4|V5IRT4_HUMAN" 3 806.4287 0.14 48335 15032 2 806.428009 404.2216 Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1 5.84 3157.2 - 1.15E+06 - - - -0.7986 - 1.165 0.051 - 145 1 2 0 -0.0006 7 0 0 0 8.14E+06 5.76E+07 - - - -0.0986 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.15038.15038.2 0.0333 12-Sep K.WTNLLYK[136.11].A sp|O75683|SURF6_HUMAN 1 944.5211 1.87 48339 15038 2 944.519376 473.2678 Surfeit locus protein 6 OS=Homo sapiens OX=9606 GN=SURF6 PE=1 SV=3 8.59 3158 - 862525 - - - -1.8284 - 1.501 0.324 - 184.4 1 2 0 -0.0017 7 0 0 0 3.20E+07 1.71E+07 - - - 2.7204 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.15045.15045.2 0.0792 14-Sep R.VGEIVVFR[166.11].L "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 927.5417 1.98 48344 15045 2 927.543425 464.7781 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.97 3158.8 - 2.65E+06 - - - 1.836 - 1.612 0.366 - 309.1 1 2 0 0.0017 8 0 0 0 1.01E+08 5.13E+07 - - - 3.1838 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.15047.15047.2 0.00524 14-Sep R.LLEIVSYK.L "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 963.5641 1.08 48346 15047 2 963.564937 482.7893 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6 3159 - 1.07E+06 - - - 0.8853 - 1.963 0.354 - 232.4 1 2 0 0.0009 8 0 0 0 1.35E+08 1.25E+08 - - - 3.6896 0.9919 230117_WJC_METTL3_WT_vs_EV_F06.15050.15050.2 1.53 14-Jul K.GAIEVLIR.E "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 869.5335 1.15 48347 15050 2 869.534209 435.774 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 6 3159.4 - 888129 - - - 0.8706 - 1.327 0.121 - 127.7 2 2 0 0.0008 8 0 0 0 7.23E+07 6.31E+07 - - - 0.6533 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.15054.15054.2 0.00055 16-Sep K.ANPALYVLR[166.11].E sp|Q6P2Q9|PRP8_HUMAN 1 1025.5897 1.34 48349 15054 2 1025.590417 513.8021 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.79 3159.9 - 1.00E+06 - - - 0.665 - 1.619 0.387 - 261.7 1 2 0 0.0007 9 0 0 0 1.36E+08 1.01E+08 - - - 3.2931 0.9928 230117_WJC_METTL3_WT_vs_EV_F06.15064.15064.2 0.475 12-Aug K.MDLLLTK[136.11].T "sp|Q6P3W7|SCYL2_HUMAN,tr|H0YIK6|H0YIK6_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 840.487 0.83 48355 15064 2 840.488022 421.2508 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.59 3161.2 - 3.21E+06 - - - 1.185 - 1.346 0.098 - 204.3 1 2 0 0.001 7 0 0 0 1.05E+08 1.27E+08 - - - 0.706 0.9733 230117_WJC_METTL3_WT_vs_EV_F06.15067.15067.3 0.00346 Oct-44 R.YLYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1484.8126 0.08 48358 15067 3 1484.815544 495.9448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3161.5 - 671430 - - - 1.9511 - 1.675 0.368 - 81.6 1 2 1 0.0029 12 0 0 0 1.28E+07 1.62E+08 - - - 4.0718 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.15071.15071.2 0.422 14-Oct K.GAIEVLIR[166.11].E "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 879.5417 1.15 48360 15071 2 879.542481 440.7781 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 6 3161.9 - 1.74E+06 - - - 0.8629 - 1.86 0.185 - 269.9 1 2 0 0.0008 8 0 0 0 7.23E+07 6.31E+07 - - - 2.2788 0.9365 230117_WJC_METTL3_WT_vs_EV_F06.15072.15072.2 3.32 14-Jun K.LLIESLEK.Y "sp|Q8TC07|TBC15_HUMAN,tr|F8VV61|F8VV61_HUMAN,tr|C9JA93|C9JA93_HUMAN" 3 943.559 2.35 48361 15072 2 943.561844 472.7868 TBC1 domain family member 15 OS=Homo sapiens OX=9606 GN=TBC1D15 PE=1 SV=2 4.53 3162.1 - 470499 - - - 3.0152 - 1.174 0.072 - 58.6 9 2 0 0.0028 8 0 0 0 4.79E+07 2.04E+07 - - - -0.3706 0.991 230117_WJC_METTL3_WT_vs_EV_F06.15078.15078.2 1.94 12-Jul K.TLLDSLR[166.11].S sp|Q5JTH9|RRP12_HUMAN 1 826.4788 0.7 48365 15078 2 826.479678 414.2467 RRP12-like protein OS=Homo sapiens OX=9606 GN=RRP12 PE=1 SV=2 5.5 3162.8 - 750844 - - - 1.0769 - 1.336 0.081 - 157.1 1 2 0 0.0009 7 0 0 0 4.02E+07 5.76E+07 - - - 0.5569 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.15080.15080.2 0.00726 28-Oct R.NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1656.8459 4.28 48367 15080 2 1656.847113 829.4302 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3163.1 - 435234 - - - 0.7303 - 2.044 0.415 - 179.4 1 2 0 0.0012 15 0 0 0 3.96E+07 9.27E+06 - - - 3.8634 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.15084.15084.2 0.00057 16-Aug K.ELGVGIALR.K sp|Q01469|FABP5_HUMAN 1 926.5549 12.66 48369 15084 2 926.556281 464.2847 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 6.1 3163.6 - 4.53E+06 - - - 1.4732 - 1.65 0.391 - 231.9 1 2 0 0.0014 9 0 0 0 2.13E+08 1.68E+07 - - - 3.3773 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.15085.15085.2 0.165 14-Jul K.FLVGFTNK[136.11].G "sp|P43307|SSRA_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|C9J5W0|C9J5W0_HUMAN" 6 932.5211 1.44 48370 15085 2 932.522425 467.2678 Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3 8.75 3163.7 - 1.58E+06 - - - 1.4177 - 1.466 0.325 - 138.3 1 2 0 0.0013 8 0 0 0 3.60E+08 2.49E+08 - - - 2.5948 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.15086.15086.2 1.36 12-Jul R.LIVDVIR.F "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 826.5276 1.19 48371 15086 2 826.527864 414.2711 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.84 3163.8 - 1.21E+06 - - - 0.2722 - 1.537 0.15 - 146.6 1 2 0 0.0002 7 0 0 0 1.50E+08 1.26E+08 - - - 1.5108 0.9842 230117_WJC_METTL3_WT_vs_EV_F06.15087.15087.2 0.612 12-Jul K.LYGFPYK[136.11].L "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 894.4731 0.95 48372 15087 2 894.476419 448.2438 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 8.5 3163.9 - 822423 - - - 3.7217 - 1.19 0.178 - 125.8 1 2 0 0.0033 7 0 0 0 3.83E+07 4.02E+07 - - - 0.9058 0.9877 230117_WJC_METTL3_WT_vs_EV_F06.15088.15088.2 0.418 16-Aug K.MLLYTEVTR[166.11].Y "sp|P31150|GDIA_HUMAN,sp|P50395|GDIB_HUMAN,tr|G5E9U5|G5E9U5_HUMAN,tr|Q5SX86|Q5SX86_HUMAN,tr|Q5SX90|Q5SX90_HUMAN,tr|V9GYF8|V9GYF8_HUMAN,tr|V9GYJ7|V9GYJ7_HUMAN" 7 1134.5983 1.2 48373 15088 2 1134.6014 568.3064 Rab GDP dissociation inhibitor alpha OS=Homo sapiens OX=9606 GN=GDI1 PE=1 SV=2 5.75 3164 - 733806 - - - 2.7754 - 1.314 0.112 - 123.4 1 2 0 0.0031 9 0 0 0 3.52E+07 2.94E+07 - - - 0.6573 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15094.15094.2 0.000882 16-Aug R.AFGYYGPLR.S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1042.5236 1.01 48377 15094 2 1042.524953 522.2691 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3164.8 - 3.12E+06 - - - 1.2825 - 1.323 0.423 - 257.2 1 2 0 0.0013 9 0 0 0 1.70E+09 1.68E+09 - - - 2.9746 1 230117_WJC_METTL3_WT_vs_EV_F06.15097.15097.2 0.00477 28-Dec R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 2.39 48380 15097 2 1646.838065 824.4261 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3165.1 - 371746 - - - 0.2623 - 2.401 0.477 - 274.8 1 2 0 0.0004 15 0 0 0 1.48E+07 6.19E+06 - - - 4.7174 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.15100.15100.2 0.278 16-Sep K.LQVALGELR[166.11].R sp|P19474|RO52_HUMAN 1 1007.6003 1.36 48381 15100 2 1007.60132 504.8074 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 6 3165.5 - 1.01E+06 - - - 1.0123 - 1.916 0.164 - 243.5 1 2 0 0.001 9 0 0 0 2.46E+07 1.81E+07 - - - 2.1332 0.8921 230117_WJC_METTL3_WT_vs_EV_F06.15101.15101.2 0.0341 14-Aug Y.TVVYFPVR[166.11].G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 989.5574 1.36 48382 15101 2 989.557966 495.786 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 8.41 3165.6 - 343875 - - - 0.6003 - 1.438 0.264 - 197.1 1 1 0 0.0006 8 0 0 0 3.10E+07 2.28E+07 - - - 2.0863 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.15112.15112.2 0.17 12-Jun R.QMSLLLR.R sp|P25705|ATPA_HUMAN 1 859.495 1.57 48389 15112 2 859.496088 430.7548 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 9.75 3167 - 5.63E+06 - - - 1.3147 - 1.457 0.171 - 228.9 1 2 0 0.0011 7 0 0 0 3.16E+08 2.01E+08 - - - 1.4962 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.15118.15118.2 0.214 14-Sep K.FLVGFTNK.G "sp|P43307|SSRA_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|C9J5W0|C9J5W0_HUMAN" 6 924.5069 1.4 48393 15118 2 924.508502 463.2607 Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3 8.75 3167.7 - 9.79E+06 - - - 1.7296 - 1.403 0.198 - 293.6 1 2 0 0.0016 8 0 0 0 3.47E+08 2.48E+08 - - - 1.5242 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.15120.15120.2 0.0129 14-Jul K.NVPYVFVR.S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 992.5444 1.14 48395 15120 2 992.545914 497.2795 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3167.9 - 790160 - - - 1.5747 - 1.279 0.305 - 212.1 1 2 0 0.0016 8 0 0 0 4.42E+08 3.89E+08 - - - 2.0354 0.9776 230117_WJC_METTL3_WT_vs_EV_F06.15136.15136.2 10.8 12-Jun R.LIVDVIR[166.11].F "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 836.5359 1.19 48402 15136 2 836.535268 419.2752 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.84 3170.1 - 2.47E+06 - - - -0.7663 - 1.428 0.062 - 118.8 2 2 0 -0.0006 7 0 0 0 1.50E+08 1.25E+08 - - - 0.4931 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.15138.15138.2 0.0194 14-Jul K.AFAMIIDK.L "sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BND9|H3BND9_HUMAN" 8 907.4837 2.52 48403 15138 2 907.485322 454.7491 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 5.88 3170.3 - 4.21E+06 - - - 1.7598 - 1.583 0.382 - 156.3 1 2 0 0.0016 8 0 0 0 1.51E+08 6.01E+07 - - - 3.2472 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.15140.15140.2 0.000237 16-Sep R.AFSYYGPLR[166.11].T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1082.5425 0.37 48405 15140 2 1082.543428 542.2785 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3170.5 - 331161 - - - 0.9025 - 1.745 0.455 - 197.6 1 2 0 0.001 9 0 0 0 7.13E+05 1.95E+06 - - - 4.012 1 230117_WJC_METTL3_WT_vs_EV_F06.15149.15149.2 4.99E-06 16-Nov K.YMAC[160.03]C[160.03]LLYR.G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1248.5454 3.15 48412 15149 2 1248.546259 625.28 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3171.3 - 716438 - - - 0.7232 - 1.91 0.606 - 496.3 1 2 0 0.0009 9 0 0 0 3.33E+08 1.06E+08 - - - 5.3887 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.15150.15150.2 2.13E-05 16-Jul K.YMAC[160.03]C[160.03]LLYR[166.11].G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1258.5536 3.15 48413 15150 2 1258.555856 630.2841 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3171.5 - 236347 - - - 1.7719 - 1.611 0.56 - 152.6 1 2 0 0.0022 9 0 0 0 3.33E+08 1.06E+08 - - - 4.556 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15153.15153.2 0.0346 16-Oct R.LLGYVATLK[136.11].D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 984.6099 2.6 48414 15153 2 984.611002 493.3122 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 8.59 3171.9 - 4.13E+06 - - - 1.1009 - 1.693 0.34 - 200.8 1 2 0 0.0011 9 0 0 0 4.11E+08 1.58E+08 - - - 3.0751 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.15154.15154.2 1.27E-06 20-Dec R.VFSGLVSTGLK.V sp|P13639|EF2_HUMAN 1 1106.6336 4.03 48415 15154 2 1106.63573 554.3241 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.72 3172 - 1.19E+06 - - - 1.9609 - 2.183 0.382 - 404.6 1 2 0 0.0022 11 0 0 0 1.33E+08 3.30E+07 - - - 3.9737 0.9898 230117_WJC_METTL3_WT_vs_EV_F06.15163.15163.2 2.28 12-Jul K.NLILVVR[166.11].G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 835.5519 1.18 48420 15163 2 835.552648 418.7832 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3173.1 - 5.97E+06 - - - 0.9036 - 1.409 0.049 - 244.6 1 2 0 0.0008 7 0 0 0 2.83E+08 2.40E+08 - - - 0.4891 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.15167.15167.2 0.354 12-Aug R.FAVFIEK.V sp|Q16352|AINX_HUMAN 1 852.4745 0.92 48422 15167 2 852.474654 427.2445 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 6 3173.5 - 5.55E+06 - - - 0.1326 - 1.769 0.197 - 220.5 1 2 0 0.0001 7 0 0 0 1.64E+08 1.77E+08 - - - 2.3034 0.9866 230117_WJC_METTL3_WT_vs_EV_F06.15168.15168.2 2.57 12-Jul K.NLILVVR.G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 825.5436 1.18 48423 15168 2 825.5441 413.7791 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3173.6 - 6.57E+06 - - - 0.5778 - 1.391 0.037 - 180 1 2 0 0.0005 7 0 0 0 2.83E+08 2.40E+08 - - - 0.3598 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.15170.15170.2 0.0611 20-Oct R.IALTDNALIAR[166.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1179.6851 0.9 48425 15170 2 1179.68594 590.8498 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3173.8 - 198789 - - - 0.7188 - 1.888 0.214 - 237.7 1 2 0 0.0008 11 0 0 0 2.85E+07 3.17E+07 - - - 2.3406 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.15174.15174.2 7.01E-05 20-Dec R.VFSGLVSTGLK[136.11].V sp|P13639|EF2_HUMAN 1 1114.6478 4.04 48427 15174 2 1114.651555 558.3312 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.72 3174.3 - 1.21E+06 - - - 3.4047 - 2.072 0.445 - 412 1 2 0 0.0038 11 0 0 0 1.33E+08 3.30E+07 - - - 4.2974 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.15176.15176.2 0.00441 12-Jul K.EILFYDR.L sp|Q08J23|NSUN2_HUMAN 1 954.4811 1.9 48428 15176 2 954.481157 478.2478 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.37 3174.5 - 3.95E+06 - - - 0.0786 - 1.445 0.416 - 226.8 1 2 0 0.0001 7 0 0 0 1.68E+08 8.83E+07 - - - 3.2799 0.9897 230117_WJC_METTL3_WT_vs_EV_F06.15183.15183.2 3.07 12-Jun K.EILFYDR[166.11].L sp|Q08J23|NSUN2_HUMAN 1 964.4894 1.9 48433 15183 2 964.490705 483.252 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.37 3175.3 - 2.03E+06 - - - 1.4028 - 1.292 0.081 - 153.7 1 2 0 0.0014 7 0 0 0 1.68E+08 8.83E+07 - - - 0.4506 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15188.15188.2 0.000127 16-Aug R.AFGYYGPLR[166.11].S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1052.5319 1.02 48436 15188 2 1052.532149 527.2732 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3175.8 - 3.39E+07 - - - 0.2499 - 1.577 0.393 - 279.7 1 2 0 0.0003 9 0 0 0 1.72E+09 1.68E+09 - - - 3.2615 0.9939 230117_WJC_METTL3_WT_vs_EV_F06.15189.15189.2 0.276 14-Aug K.LIINSLYK[136.11].N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 970.5943 0.98 48437 15189 2 970.595603 486.3044 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3175.9 - 1.63E+06 - - - 1.3754 - 1.205 0.166 - 121.1 1 2 0 0.0013 8 0 0 0 2.78E+08 2.83E+08 - - - 0.8291 0.9921 230117_WJC_METTL3_WT_vs_EV_F06.15193.15193.2 0.0152 12-Aug R.FLTVMMK.H "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 868.4551 1.26 48439 15193 2 868.456043 435.2348 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.75 3176.5 - 2.37E+06 - - - 1.1238 - 1.387 0.077 - 212.1 1 2 0 0.001 7 0 0 0 4.20E+08 3.33E+08 - - - 0.646 0.9668 230117_WJC_METTL3_WT_vs_EV_F06.15194.15194.2 3.59 14-Aug K.GLVFLNGK.L sp|L0R8F8|MIDUO_HUMAN 1 846.4963 1.94 48440 15194 2 846.494635 424.2554 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 8.75 3176.5 - 1.63E+06 - - - -2.013 - 1.463 0.079 - 222.4 1 2 0 -0.0017 8 0 0 0 1.25E+08 6.47E+07 - - - 0.7715 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.15201.15201.2 0.0294 12-Jul R.FLTVMMK[136.11].H "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 876.4693 1.26 48443 15201 2 876.47018 439.2419 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.75 3177.4 - 3.17E+06 - - - 1.0417 - 1.384 0.378 - 156.3 1 2 0 0.0009 7 0 0 0 4.21E+08 3.34E+08 - - - 2.8623 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.15203.15203.2 0.0241 14-May K.LIINSLYK.N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 962.5801 0.98 48444 15203 2 962.580498 482.2973 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3177.6 - 2.78E+06 - - - 0.4467 - 1.191 0.323 - 51.6 1 2 0 0.0004 8 0 0 0 2.78E+08 2.83E+08 - - - 1.9537 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.15204.15204.2 0.00366 20-Sep R.IALTDNALIAR.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1169.6768 0.9 48445 15204 2 1169.678409 585.8457 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3177.8 - 748376 - - - 1.3568 - 2.005 0.298 - 175.7 1 2 0 0.0016 11 0 0 0 2.85E+07 3.17E+07 - - - 3.1234 0.9959 230117_WJC_METTL3_WT_vs_EV_F06.15207.15207.2 0.832 16-Aug R.LLLPTPTVK.Q "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 980.627 2.42 48446 15207 2 980.627632 491.3208 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 3178.2 - 7.33E+06 - - - 0.6261 - 1.457 0.148 - 212.5 1 2 0 0.0006 9 0 0 0 6.11E+08 2.52E+08 - - - 1.2228 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.15210.15210.2 0.00429 14-Oct K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 3.31 48449 15210 2 843.506456 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 3178.3 - 3.19E+06 - - - -0.134 - 2.059 0.364 - 305.6 1 2 0 -0.0001 8 0 0 0 2.20E+08 6.64E+07 - - - 3.9077 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.15216.15216.2 0.0172 16-Sep R.LPEAAFLAR.T "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 986.5549 2.79 48452 15216 2 986.555207 494.2847 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 6 3179 - 3.10E+06 - - - 0.295 - 1.469 0.306 - 225.3 1 2 0 0.0003 9 0 0 0 3.31E+08 1.19E+08 - - - 2.4136 0.991 230117_WJC_METTL3_WT_vs_EV_F06.15222.15222.2 4.69 12-Jul R.LYIWSGR[166.11].D "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 903.4842 2.46 48455 15222 2 903.484846 452.7494 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 8.75 3179.7 - 950425 - - - 0.7062 - 1.268 0.11 - 191.9 1 2 0 0.0006 7 0 0 0 1.50E+08 6.09E+07 - - - 0.6056 0.9839 230117_WJC_METTL3_WT_vs_EV_F06.15231.15231.2 5.05 14-May K.NVPYVFVR[166.11].S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 1002.5526 1.31 48459 15231 2 1002.553298 502.2836 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3180.7 - 4.12E+06 - - - 0.6753 - 1.009 0.155 - 92.3 1 2 0 0.0007 8 0 0 0 3.90E+08 2.98E+08 - - - 0.2126 0.964 230117_WJC_METTL3_WT_vs_EV_F06.15238.15238.2 1.56 12-May K.LVFDGLR[166.11].K sp|P15924|DESP_HUMAN 1 828.4733 46.49 48462 15238 2 828.474027 415.2439 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.84 3181.5 - 1.51E+06 - - - 0.8679 - 1.08 0.078 - 79.8 3 2 0 0.0007 7 0 0 0 2.68E+09 5.77E+07 - - - -0.3524 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.15252.15252.2 0.00352 16-Nov R.LPEAAFLAR[166.11].T "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 996.5632 2.81 48466 15252 2 996.56476 499.2889 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 6 3183.5 - 3.06E+06 - - - 1.5794 - 1.774 0.26 - 447.1 1 2 0 0.0016 9 0 0 0 3.31E+08 1.18E+08 - - - 2.6193 0.9768 230117_WJC_METTL3_WT_vs_EV_F06.15267.15267.2 0.398 14-Aug R.SVLLEAIR.K sp|Q92558|WASF1_HUMAN 1 899.544 1.33 48474 15267 2 899.542108 450.7793 Wiskott-Aldrich syndrome protein family member 1 OS=Homo sapiens OX=9606 GN=WASF1 PE=1 SV=1 5.72 3185.5 - 701336 - - - -2.1222 - 1.557 0.098 - 184.7 1 2 0 -0.0019 8 0 0 0 2.22E+07 1.67E+07 - - - 1.0996 0.9811 230117_WJC_METTL3_WT_vs_EV_F06.15268.15268.2 0.0056 22-Aug K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 0.99 48475 15268 2 1277.754019 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3185.6 - 342484 - - - 3.4639 - 1.509 0.071 - 103.4 1 2 0 0.0044 12 0 0 0 1.02E+07 1.03E+07 - - - 0.6466 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.15273.15273.2 0.000996 22-Nov K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 85.01 48478 15273 2 1356.690546 679.3515 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3186.2 - 328536 - - - 1.5015 - 2.34 0.374 - 361.5 1 2 0 0.002 12 0 0 0 1.81E+07 2.13E+05 - - - 4.0396 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.15274.15274.2 0.418 18-Sep K.IVLLSANSIR.A "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 1084.6604 2.36 48479 15274 2 1084.66044 543.3375 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 9.75 3186.4 - 1.14E+06 - - - -0.0037 - 1.687 0.252 - 222.7 1 2 0 0 10 0 0 0 3.78E+07 1.60E+07 - - - 2.362 0.9968 230117_WJC_METTL3_WT_vs_EV_F06.15275.15275.2 0.0247 16-Aug R.YLYLSTMER.S "sp|Q10570|CPSF1_HUMAN,tr|A0A087X101|A0A087X101_HUMAN" 2 1174.5692 1.03 48480 15275 2 1174.572481 588.2919 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6 3186.5 - 595626 - - - 2.7542 - 1.332 0.248 - 225.9 1 2 0 0.0032 9 0 0 0 6.80E+06 6.59E+06 - - - 1.7011 0.9821 230117_WJC_METTL3_WT_vs_EV_F06.15280.15280.2 0.488 12-Jun R.IYLYLTK.V "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 912.5321 1.89 48483 15280 2 912.533215 457.2733 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.5 3187.1 - 1.46E+06 - - - 1.2712 - 1.269 0.038 - 121.5 1 2 0 0.0012 7 0 0 0 7.56E+07 3.99E+07 - - - 0.0761 0.9947 230117_WJC_METTL3_WT_vs_EV_F06.15282.15282.2 3.76 12-Aug R.IYLYLTK[136.11].V "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 920.5463 1.9 48485 15282 2 920.547971 461.2804 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.5 3187.3 - 911355 - - - 1.8641 - 1.517 0.084 - 216.8 1 2 0 0.0017 7 0 0 0 7.55E+07 3.98E+07 - - - 0.9813 0.997 230117_WJC_METTL3_WT_vs_EV_F06.15288.15288.2 0.646 12-Aug R.WGGLDLR[166.11].R sp|Q9H7N4|SFR19_HUMAN 1 825.4373 0.86 48489 15288 2 825.438178 413.7259 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.84 3187.9 - 844570 - - - 1.1158 - 1.419 0.168 - 261.6 1 2 0 0.0009 7 0 0 0 6.67E+07 7.75E+07 - - - 1.3904 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.15292.15292.2 0.00265 22-Aug K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 0.99 48493 15292 2 1287.762064 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3188.4 - 246024 - - - 3.2623 - 1.621 0.311 - 137.1 1 2 0 0.0042 12 0 0 0 1.02E+07 1.03E+07 - - - 2.6077 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.15296.15296.2 1.37E-05 14-Aug R.NIVLYDMR.Q "sp|Q9NV06|DCA13_HUMAN,tr|A0A087WT20|A0A087WT20_HUMAN,tr|A0A087X1F8|A0A087X1F8_HUMAN" 3 1022.5219 999 48495 15296 2 1022.526144 512.2682 DDB1- and CUL4-associated factor 13 OS=Homo sapiens OX=9606 GN=DCAF13 PE=1 SV=2 5.84 3188.9 - 430464 - - - 4.1495 - 1.557 0.46 - 201.5 1 2 0 0.0042 8 0 0 0 1.40E+07 0.00E+00 - - - 3.7726 0.9536 230117_WJC_METTL3_WT_vs_EV_F06.15298.15298.2 4.75 12-May K.FLLLQQK[136.11].Y "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 896.5575 1.95 48497 15298 2 896.560324 449.286 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 8.75 3189.1 - 558258 - - - 3.1621 - 1.022 0.125 - 70 2 2 0 0.0028 7 0 0 0 8.49E+07 4.34E+07 - - - -0.1022 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.15300.15300.2 0.00872 12-Jul R.WFVTC[160.03]VR.Q "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN,tr|A0A140T954|A0A140T954_HUMAN" 3 966.4746 0.6 48499 15300 2 966.476159 484.2446 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 8.25 3189.4 - 365912 - - - 1.6565 - 1.27 0.37 - 134.9 1 2 0 0.0016 7 0 0 0 1.13E+07 1.89E+07 - - - 2.5307 0.9647 230117_WJC_METTL3_WT_vs_EV_F06.15304.15304.2 0.00257 16-Oct R.PAVLSGYFK.Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 980.5331 1.05 48500 15304 2 980.535715 491.2738 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.01 3190 - 3.10E+06 - - - 2.6486 - 1.946 0.418 - 360.1 1 1 0 0.0026 9 0 0 0 2.12E+08 2.03E+08 - - - 4.0537 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.15305.15305.2 0.0369 14-Jul R.LLLNYAVR.L "sp|Q92989|CLP1_HUMAN,tr|E9PL17|E9PL17_HUMAN,tr|E9PKV5|E9PKV5_HUMAN" 3 960.5757 6.42 48501 15305 2 960.578548 481.2951 Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1 8.75 3190.1 - 771484 - - - 3.0149 - 1.552 0.236 - 147.5 1 2 0 0.0029 8 0 0 0 2.43E+08 3.79E+07 - - - 2.1088 0.996 230117_WJC_METTL3_WT_vs_EV_F06.15306.15306.2 0.0589 14-Sep K.LGFESIYK.L "sp|P49643|PRI2_HUMAN,tr|A0A5F9ZHU7|A0A5F9ZHU7_HUMAN" 2 955.5015 1.89 48502 15306 2 955.504801 478.758 DNA primase large subunit OS=Homo sapiens OX=9606 GN=PRIM2 PE=1 SV=2 6 3190.2 - 715919 - - - 3.4715 - 1.56 0.206 - 186.1 1 2 0 0.0033 8 0 0 0 2.51E+07 1.33E+07 - - - 1.9026 0.9953 230117_WJC_METTL3_WT_vs_EV_F06.15310.15310.2 0.162 12-Sep R.WGGLDLR.R sp|Q9H7N4|SFR19_HUMAN 1 815.429 0.87 48504 15310 2 815.431018 408.7218 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.84 3190.8 - 3.08E+06 - - - 2.4907 - 1.327 0.181 - 363.8 1 2 0 0.002 7 0 0 0 6.73E+07 7.75E+07 - - - 1.2737 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.15312.15312.2 0.000234 18-Oct R.LITLEEEMTK.Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1205.6213 2.69 48506 15312 2 1205.625742 603.8179 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3191 - 553417 - - - 3.6504 - 1.984 0.482 - 278.2 1 2 0 0.0044 10 0 0 0 3.07E+07 1.14E+07 - - - 4.512 0.8988 230117_WJC_METTL3_WT_vs_EV_F06.15321.15321.2 1.45 16-Jun R.ALVQSLLAK.E sp|Q9NX46|ADPRS_HUMAN 1 941.591 3.02 48513 15321 2 941.593515 471.8028 ADP-ribose glycohydrolase ARH3 OS=Homo sapiens OX=9606 GN=ADPRS PE=1 SV=1 8.8 3192.1 - 328105 - - - 2.7061 - 1.093 0.045 - 67.9 9 2 0 0.0025 9 0 0 0 1.31E+07 4.35E+06 - - - -0.7964 0.9675 230117_WJC_METTL3_WT_vs_EV_F06.15328.15328.3 0.682 Dec-56 K.LVEALC[160.03]AEHQINLIK.V sp|P25398|RS12_HUMAN 1 1749.9447 3.52 48518 15328 3 1749.948432 584.3222 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.4 3193 - 494986 - - - 2.1092 - 1.753 0.071 - 95 1 2 0 0.0037 15 0 0 0 4.33E+06 1.23E+06 - - - 0.7953 0.9884 230117_WJC_METTL3_WT_vs_EV_F06.15332.15332.2 0.451 12-Jul R.LIMQYLK[136.11].E sp|Q2TAY7|SMU1_HUMAN 1 915.5343 0.97 48520 15332 2 915.536345 458.7744 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.59 3193.5 - 2.96E+06 - - - 2.2217 - 1.23 0.109 - 126.5 1 2 0 0.002 7 0 0 0 7.94E+07 8.22E+07 - - - 0.5014 0.8594 230117_WJC_METTL3_WT_vs_EV_F06.15337.15337.4 0.00731 Nov-96 T.LLLIILTDVFIISTVLR.L sp|Q8NGY0|O10X1_HUMAN 1 1941.2278 999 48523 15337 4 1941.238687 486.3142 Olfactory receptor 10X1 OS=Homo sapiens OX=9606 GN=OR10X1 PE=3 SV=2 5.84 3194.1 - 390468 - - - 5.597 - 1.694 0.322 - 52.1 1 1 0 0.0109 17 0 0 0 1.89E+07 0.00E+00 - - - 2.2087 0.9926 230117_WJC_METTL3_WT_vs_EV_F06.15340.15340.2 0.00586 18-Jul K.LVIIEGDLER[166.11].T "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1165.6582 1.24 48525 15340 2 1165.664424 583.8364 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.14 3194.5 - 476114 - - - 5.3318 - 1.594 0.302 - 121 1 2 0 0.0062 10 0 0 0 2.64E+07 2.13E+07 - - - 2.5711 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.15341.15341.2 0.000259 18-Sep R.LITLEEEMTK[136.11].Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1213.6355 2.69 48526 15341 2 1213.638543 607.825 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3194.6 - 675365 - - - 2.4736 - 1.772 0.5 - 205.2 1 2 0 0.003 10 0 0 0 3.07E+07 1.14E+07 - - - 4.33 0.979 230117_WJC_METTL3_WT_vs_EV_F06.15346.15346.2 0.0558 14-Aug R.GILYC[160.03]YMR[166.11].Q "sp|Q93100|KPBB_HUMAN,tr|H3BV13|H3BV13_HUMAN,tr|I3NHZ9|I3NHZ9_HUMAN,tr|H3BQ89|H3BQ89_HUMAN" 4 1084.5073 0.49 48529 15346 2 1084.512498 543.2609 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 8.2 3195.3 - 266293 - - - 4.7671 - 1.285 0.195 - 160.1 1 2 0 0.0052 8 0 0 0 3.17E+06 6.50E+06 - - - 1.2359 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.15353.15353.2 0.00129 16-Oct K.LGEWVGLC[160.03]K[136.11].L sp|P25398|RS12_HUMAN 1 1068.5518 2.2 48534 15353 2 1068.553656 535.2832 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3196.1 - 5.64E+06 - - - 1.7819 - 2.04 0.466 - 280 1 2 0 0.0019 9 0 0 0 3.77E+08 1.71E+08 - - - 4.5449 1 230117_WJC_METTL3_WT_vs_EV_F06.15359.15359.2 1.90E-05 16-Dec K.LGEWVGLC[160.03]K.L sp|P25398|RS12_HUMAN 1 1060.5376 2.2 48538 15359 2 1060.539466 531.2761 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3196.8 - 1.33E+07 - - - 1.8047 - 2.274 0.503 - 598.9 1 2 0 0.0019 9 0 0 0 3.77E+08 1.72E+08 - - - 5.1323 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.15361.15361.2 0.00272 14-Aug R.GFTLVGMK.M "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 851.4575 0.96 48540 15361 2 851.4589 426.736 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.75 3196.9 - 2.37E+06 - - - 1.6325 - 1.594 0.386 - 232.6 1 2 0 0.0014 8 0 0 0 1.17E+09 1.21E+09 - - - 3.2977 0.8902 230117_WJC_METTL3_WT_vs_EV_F06.15362.15362.2 0.00291 16-Sep R.AVFPSIVGR[166.11].P "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 31 954.5526 1.24 48541 15362 2 954.556282 478.2836 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 9.79 3197 - 1.33E+06 - - - 3.8353 - 1.677 0.366 - 296.7 1 1 0 0.0037 9 0 0 0 1.40E+09 1.13E+09 - - - 3.2389 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.15369.15369.2 0.248 18-Aug K.SYLYPSTLVR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1197.6394 0.36 48546 15369 2 1197.641083 599.827 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 3197.8 - 1.47E+06 - - - 1.427 - 1.781 0.283 - 265.7 1 2 0 0.0017 10 0 0 0 5.26E+08 1.45E+09 - - - 2.7418 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.15370.15370.2 0.0208 20-Sep R.LVEMASSLAIR.E "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1188.6536 34.64 48547 15370 2 1188.652824 595.3341 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3197.9 - 338463 - - - -0.6899 - 1.663 0.379 - 221.9 1 2 0 -0.0008 11 0 0 0 7.29E+06 2.11E+05 - - - 3.216 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.15381.15381.2 0.165 12-Jul K.TSILVFK[136.11].D sp|Q9BRS2|RIOK1_HUMAN 1 814.5044 0.62 48555 15381 2 814.50734 408.2595 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 8.41 3199.1 - 2.94E+06 - - - 3.6206 - 1.851 0.311 - 232.6 1 2 0 0.0029 7 0 0 0 5.05E+07 8.20E+07 - - - 3.2881 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.15386.15386.2 0.194 16-Jun R.LLDEYNLVR.S "sp|P46531|NOTC1_HUMAN,tr|A0A7P0T8U6|A0A7P0T8U6_HUMAN,tr|A0A7P0TA56|A0A7P0TA56_HUMAN,tr|A0A7P0TB20|A0A7P0TB20_HUMAN,tr|A0A7P0T8W1|A0A7P0T8W1_HUMAN" 5 1133.6081 2.05 48558 15386 2 1133.609996 567.8113 Neurogenic locus notch homolog protein 1 OS=Homo sapiens OX=9606 GN=NOTCH1 PE=1 SV=4 4.37 3199.6 - 258432 - - - 1.6955 - 1.503 0.188 - 76.1 1 2 0 0.0019 9 0 0 0 6.20E+06 3.02E+06 - - - 1.6078 0.9953 230117_WJC_METTL3_WT_vs_EV_F06.15401.15401.2 0.0206 12-Aug K.LC[160.03]TFILK.N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 893.5045 1.22 48568 15401 2 893.507257 447.7595 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3201.5 - 703915 - - - 3.1293 - 1.534 0.158 - 135.6 1 2 0 0.0028 7 0 0 0 4.90E+07 4.02E+07 - - - 1.5629 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15408.15408.2 0.00295 14/20 K.IGLFGGAGVGK.T "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 974.5549 3.61 48573 15408 2 974.554245 488.2847 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 8.75 3202.3 - 2.07E+06 - - - -0.6885 - 2.367 0.409 - 422 1 2 0 -0.0007 11 0 0 0 1.02E+09 2.81E+08 - - - 4.3926 0.9943 230117_WJC_METTL3_WT_vs_EV_F06.15409.15409.2 0.0957 12-Jul K.LC[160.03]TFILK[136.11].N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 901.5187 1.23 48574 15409 2 901.519957 451.7666 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3202.4 - 1.68E+06 - - - 1.4376 - 1.484 0.08 - 112.8 1 2 0 0.0013 7 0 0 0 4.69E+07 3.83E+07 - - - 0.8822 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.15414.15414.2 0.00109 22-Dec K.AVASAAAALVLK.A sp|Q9Y490|TLN1_HUMAN 1 1083.6652 1.06 48577 15414 2 1083.66752 542.8399 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.8 3203.1 - 479481 - - - 2.1455 - 2.073 0.381 - 380 1 2 0 0.0023 12 0 0 0 2.82E+07 2.66E+07 - - - 3.7725 0.9934 230117_WJC_METTL3_WT_vs_EV_F06.15415.15415.2 0.519 12-Jun R.YAFDFAR.E "sp|Q92564|DCNL4_HUMAN,sp|Q9BTE7|DCNL5_HUMAN,tr|H0YCN4|H0YCN4_HUMAN,tr|H0Y9C5|H0Y9C5_HUMAN,tr|E9PM04|E9PM04_HUMAN,tr|H0Y907|H0Y907_HUMAN" 6 888.413 1.95 48578 15415 2 888.414296 445.2138 DCN1-like protein 4 OS=Homo sapiens OX=9606 GN=DCUN1D4 PE=1 SV=2 5.84 3203.1 - 899552 - - - 1.4554 - 1.101 0.193 - 120.9 1 2 0 0.0013 7 0 0 0 2.28E+07 1.17E+07 - - - 0.771 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.15417.15417.2 0.0215 18-Sep K.VLFTGVVDAR.G sp|Q14676|MDC1_HUMAN 1 1075.6026 2.56 48579 15417 2 1075.603006 538.8086 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 5.81 3203.4 - 840848 - - - 0.3821 - 1.847 0.321 - 239.7 1 2 0 0.0004 10 0 0 0 5.88E+07 2.30E+07 - - - 3.1244 0.9924 230117_WJC_METTL3_WT_vs_EV_F06.15419.15419.2 0.674 14-Aug K.ILEDSFLK.S sp|Q9Y6X8|ZHX2_HUMAN 1 963.5277 2.06 48580 15419 2 963.530405 482.7711 Zinc fingers and homeoboxes protein 2 OS=Homo sapiens OX=9606 GN=ZHX2 PE=1 SV=1 4.37 3203.6 - 1.20E+06 - - - 2.8095 - 1.279 0.168 - 135.9 1 2 0 0.0027 8 0 0 0 2.43E+07 1.18E+07 - - - 1.0232 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15424.15424.2 0.0533 14-Aug R.IGQFVFAR.D sp|Q9NRN7|ADPPT_HUMAN 1 936.5181 6.96 48584 15424 2 936.519698 469.2663 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2 9.75 3203.9 - 9.47E+06 - - - 1.6668 - 1.772 0.298 - 198.6 1 2 0 0.0016 8 0 0 0 1.91E+08 2.74E+07 - - - 2.967 0.9832 230117_WJC_METTL3_WT_vs_EV_F06.15425.15425.2 0.69 14-Aug K.AGLSVLLK.A "sp|Q969N2|PIGT_HUMAN,tr|A0A1W2PRZ8|A0A1W2PRZ8_HUMAN,tr|H7C2Y2|H7C2Y2_HUMAN,tr|A0A1W2PPR6|A0A1W2PPR6_HUMAN,tr|A0A1W2PPS0|A0A1W2PPS0_HUMAN,tr|A0A1W2PR92|A0A1W2PR92_HUMAN,tr|A0A1W2PPI8|A0A1W2PPI8_HUMAN,tr|A0A1W2PRG1|A0A1W2PRG1_HUMAN,tr|A0A1W2PRV7|A0A1W2PRV7_HUMAN,tr|A0A1W2PQ52|A0A1W2PQ52_HUMAN,tr|A0A1W2PRH2|A0A1W2PRH2_HUMAN,tr|A0A1W2PNP0|A0A1W2PNP0_HUMAN,tr|A0A1W2PNW9|A0A1W2PNW9_HUMAN,tr|A0A1W2PP57|A0A1W2PP57_HUMAN,tr|A0A1W2PPQ7|A0A1W2PPQ7_HUMAN,tr|A0A1W2PQ29|A0A1W2PQ29_HUMAN,tr|A0A1W2PQN1|A0A1W2PQN1_HUMAN,tr|A0A1W2PPC3|A0A1W2PPC3_HUMAN" 18 799.5167 1.29 48585 15425 2 799.5187 400.7656 GPI transamidase component PIG-T OS=Homo sapiens OX=9606 GN=PIGT PE=1 SV=1 8.8 3204 - 1.29E+06 - - - 2.4515 - 1.337 0.072 - 113.2 2 2 0 0.002 8 0 0 0 2.97E+07 2.30E+07 - - - 0.3136 0.9608 230117_WJC_METTL3_WT_vs_EV_F06.15428.15428.2 0.234 12-Jul R.ALTALFK.E "sp|Q9UBB4|ATX10_HUMAN,tr|A0A1W2PQD2|A0A1W2PQD2_HUMAN" 2 762.464 1.56 48586 15428 2 762.468035 382.2393 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 8.8 3204.4 - 896848 - - - 5.3235 - 1.309 0.154 - 192.6 1 2 0 0.0041 7 0 0 0 5.57E+07 3.57E+07 - - - 1.0303 0.9962 230117_WJC_METTL3_WT_vs_EV_F06.15437.15437.2 0.36 12-Jun R.FLVTVIK.D "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 818.5266 1.41 48590 15437 2 818.527902 410.2706 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3205.6 - 1.86E+06 - - - 1.62 - 1.383 0.152 - 122.5 1 2 0 0.0013 7 0 0 0 1.18E+08 8.33E+07 - - - 1.1907 0.9968 230117_WJC_METTL3_WT_vs_EV_F06.15445.15445.2 0.0175 22-Aug R.IMNTFSVVPSPK.V "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 11 1318.6955 2.98 48595 15445 2 1318.699855 660.355 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3206.6 - 118488 - - - 3.2957 - 1.421 0.278 - 142.1 1 2 0 0.0043 12 0 0 0 1.05E+06 3.52E+05 - - - 2.0174 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15446.15446.2 0.00467 14-Sep R.LYNYFYDR.R "sp|Q96GD4|AURKB_HUMAN,tr|J3QR41|J3QR41_HUMAN,tr|J3QLN8|J3QLN8_HUMAN,tr|J3KTD6|J3KTD6_HUMAN,tr|J3KT86|J3KT86_HUMAN" 5 1152.524 2.22 48596 15446 2 1152.524982 577.2693 Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3 5.83 3206.8 - 483894 - - - 0.8434 - 1.494 0.372 - 318.7 1 2 0 0.001 8 0 0 0 1.33E+07 6.02E+06 - - - 2.9991 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.15451.15451.2 0.0393 12-Jul K.YIQELWR[166.11].K "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1016.5319 0.8 48599 15451 2 1016.530689 509.2732 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 6 3207.3 - 5.58E+06 - - - -1.1775 - 1.54 0.353 - 202.6 1 2 0 -0.0012 7 0 0 0 1.85E+08 2.32E+08 - - - 3.016 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.15452.15452.2 0.316 12-Jul R.ALTALFK[136.11].E "sp|Q9UBB4|ATX10_HUMAN,tr|A0A1W2PQD2|A0A1W2PQD2_HUMAN" 2 770.4782 1.56 48600 15452 2 770.479154 386.2464 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 8.8 3207.4 - 947399 - - - 1.2693 - 1.315 0.189 - 182.1 1 2 0 0.001 7 0 0 0 5.59E+07 3.59E+07 - - - 1.3043 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.15454.15454.2 0.0411 22-Jun R.LVPAAEEEELLR[166.11].E sp|Q9Y4B5|MTCL1_HUMAN 1 1377.7379 1.2 48602 15454 2 1377.74222 689.8762 Microtubule cross-linking factor 1 OS=Homo sapiens OX=9606 GN=MTCL1 PE=1 SV=5 4.09 3207.6 - 64561 - - - 3.124 - 1.42 0.285 - 90.9 1 2 0 0.0043 12 0 0 0 8.17E+05 6.83E+05 - - - 2.0673 0.9947 230117_WJC_METTL3_WT_vs_EV_F06.15458.15458.2 0.0815 14-Jun R.LLEC[160.03]YFTR[166.11].S "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1110.5407 2.25 48604 15458 2 1110.540442 556.2776 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.99 3208.1 - 563785 - - - -0.2647 - 1.367 0.185 - 77.8 1 2 0 -0.0003 8 0 0 0 3.34E+07 1.48E+07 - - - 1.3502 0.9761 230117_WJC_METTL3_WT_vs_EV_F06.15459.15459.2 20 12-Jun R.LILEALK[136.11].Q "sp|Q8IX18|DHX40_HUMAN,sp|Q6TDP4|KLH17_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|D6RJB0|D6RJB0_HUMAN,tr|H0Y9K3|H0Y9K3_HUMAN,tr|A0A3B3ISF8|A0A3B3ISF8_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN,tr|Q0VGE6|Q0VGE6_HUMAN,tr|J3QLT4|J3QLT4_HUMAN,tr|A0A3B3IT29|A0A3B3IT29_HUMAN,tr|D6R9W6|D6R9W6_HUMAN,tr|G3V0E9|G3V0E9_HUMAN" 12 806.5357 1.26 48605 15459 2 806.536393 404.2751 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 6 3208.2 - 941676 - - - 0.8704 - 1.246 0.024 - 85.8 1 2 0 0.0007 7 0 0 0 3.76E+07 2.97E+07 - - - -0.0851 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.15464.15464.2 0.0127 14-Jul R.TVEDVFLR[166.11].K sp|Q96EL2|RT24_HUMAN 1 987.5265 0.96 48608 15464 2 987.528171 494.7705 "28S ribosomal protein S24, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS24 PE=1 SV=1" 4.37 3208.8 - 1.24E+06 - - - 1.7265 - 1.712 0.305 - 128.2 1 2 0 0.0017 8 0 0 0 4.89E+07 5.07E+07 - - - 2.9148 0.9833 230117_WJC_METTL3_WT_vs_EV_F06.15468.15468.2 5.95 12-Jul R.LWISVAR[166.11].Y sp|Q15029|U5S1_HUMAN 1 853.5049 1.74 48610 15468 2 853.507026 427.7597 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 9.75 3209.3 - 5.49E+06 - - - 2.4405 - 1.3 0.06 - 208.8 1 2 0 0.0021 7 0 0 0 2.03E+08 1.17E+08 - - - 0.3148 0.9231 230117_WJC_METTL3_WT_vs_EV_F06.15470.15470.2 0.595 12-Jul R.C[160.03]ILPFDK[136.11].E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 899.4666 1.41 48612 15470 2 899.468372 450.7406 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.83 3209.4 - 1.86E+06 - - - 1.9423 - 1.01 0.014 - 218.2 1 2 0 0.0017 7 0 0 0 3.08E+08 2.19E+08 - - - -0.8246 0.9918 230117_WJC_METTL3_WT_vs_EV_F06.15477.15477.2 0.069 14-Jun K.VFPLAEYR.T sp|Q86T24|KAISO_HUMAN 1 993.5284 1.33 48617 15477 2 993.52649 497.7715 Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2 5.97 3210.3 - 623307 - - - -1.8892 - 1.467 0.225 - 151.3 1 2 0 -0.0019 8 0 0 0 4.29E+07 3.23E+07 - - - 1.858 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.15481.15481.2 1.49 14-Jul R.GLVVPVIR[166.11].N sp|P36957|ODO2_HUMAN 1 861.5675 0.95 48619 15481 2 861.56922 431.791 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3210.7 - 1.84E+06 - - - 1.9465 - 1.563 0.239 - 238.4 1 2 0 0.0017 8 0 0 0 1.41E+08 1.49E+08 - - - 2.1527 0.9918 230117_WJC_METTL3_WT_vs_EV_F06.15489.15489.2 0.0393 14-Jul R.LLFGPTVR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 911.5468 0.94 48625 15489 2 911.549122 456.7807 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3211.6 - 1.97E+06 - - - 2.5385 - 1.344 0.125 - 146.2 1 2 0 0.0023 8 0 0 0 1.52E+08 1.61E+08 - - - 0.8552 0.9252 230117_WJC_METTL3_WT_vs_EV_F06.15490.15490.3 0.0713 Dec-40 K.LKVPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1312.7391 2.03 48626 15490 3 1312.742908 438.587 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3211.7 - 453291 - - - 2.9099 - 2.025 0.267 - 223 1 2 1 0.0038 11 0 0 0 2.35E+07 1.16E+07 - - - 3.5201 1 230117_WJC_METTL3_WT_vs_EV_F06.15498.15498.2 6.53E-06 14/20 K.WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1223.643 0.91 48632 15498 2 1223.646246 612.8288 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3212.8 - 1.05E+06 - - - 2.6454 - 2.301 0.54 - 533.1 1 2 0 0.0032 11 0 0 0 1.05E+08 1.16E+08 - - - 5.2828 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.15499.15499.2 0.0588 14-Jul K.FLILNPSK.R "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 930.5539 0.79 48633 15499 2 930.555578 466.2842 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 8.75 3212.9 - 576635 - - - 1.8527 - 1.281 0.263 - 129.5 1 2 0 0.0017 8 0 0 0 3.09E+07 3.90E+07 - - - 1.7299 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.15503.15503.2 0.0321 18-Aug R.LGTVLPVIEK[136.11].E sp|O75691|UTP20_HUMAN 1 1075.6732 0.99 48637 15503 2 1075.674795 538.8439 Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3 6 3213.3 - 261004 - - - 1.4391 - 1.51 0.215 - 154.2 1 2 0 0.0015 10 0 0 0 1.85E+07 1.86E+07 - - - 1.7788 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.15506.15506.2 0.00177 14-Sep R.LGDLVWGK.L "sp|Q49A26|GLYR1_HUMAN,sp|Q9UBC3|DNM3B_HUMAN,tr|K7EQB2|K7EQB2_HUMAN,tr|K7ELL0|K7ELL0_HUMAN" 4 886.4913 0.57 48638 15506 2 886.490853 444.2529 Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4 5.84 3213.7 - 2.01E+06 - - - -0.4512 - 1.972 0.189 - 228.4 1 2 0 -0.0004 8 0 0 0 6.63E+07 1.16E+08 - - - 2.4848 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15507.15507.2 0.034 18-Sep K.ALVLTEIGPK.R sp|O14732|IMPA2_HUMAN 1 1039.6277 176.87 48639 15507 2 1039.629142 520.8211 Inositol monophosphatase 2 OS=Homo sapiens OX=9606 GN=IMPA2 PE=1 SV=1 6.05 3213.8 - 446558 - - - 1.3418 - 1.751 0.322 - 262.6 1 2 0 0.0014 10 0 0 0 1.84E+07 1.04E+05 - - - 2.9825 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.15508.15508.2 1.11 14-Aug R.GLVVPVIR.N sp|P36957|ODO2_HUMAN 1 851.5593 0.95 48640 15508 2 851.560412 426.7869 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3213.8 - 3.08E+06 - - - 1.3375 - 1.609 0.2 - 359.6 1 2 0 0.0011 8 0 0 0 1.41E+08 1.49E+08 - - - 1.9523 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.15512.15512.2 0.174 18-Sep R.ELLQESALIR.K "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 3 1170.6608 5.6 48642 15512 2 1170.661555 586.3377 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.53 3214.3 - 1.56E+06 - - - 0.6125 - 1.559 0.229 - 93.7 1 2 0 0.0007 10 0 0 0 2.83E+07 5.05E+06 - - - 1.9716 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.15520.15520.2 0.0144 22-Oct K.NYIQGINLVQAK.K "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1359.7511 5.7 48647 15520 2 1359.752903 680.8828 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 8.59 3215.2 - 215117 - - - 1.3627 - 1.312 0.284 - 153.4 1 2 0 0.0019 12 0 0 0 7.15E+06 1.26E+06 - - - 1.8525 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.15523.15523.2 0.149 14-Jul R.LLPEQLIK[136.11].E "sp|Q92621|NU205_HUMAN,sp|Q8TBZ9|TEX47_HUMAN" 2 960.6099 2.66 48649 15523 2 960.610717 481.3122 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 6 3215.6 - 1.25E+06 - - - 0.8318 - 1.132 0.33 - 94.3 1 2 0 0.0008 8 0 0 0 1.86E+08 6.98E+07 - - - 1.8521 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.15525.15525.2 0.00409 22-Oct K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.22 48650 15525 2 1277.752508 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3215.8 - 893053 - - - 2.2814 - 1.716 0.321 - 209.1 1 2 0 0.0029 12 0 0 0 8.08E+07 6.64E+07 - - - 2.8318 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.15527.15527.2 0.207 14-Aug K.YYVLNALK[136.11].H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 990.563 2.39 48651 15527 2 990.563058 496.2888 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.5 3216 - 1.07E+06 - - - 0.0909 - 1.244 0.338 - 150.3 1 2 0 0.0001 8 0 0 0 2.95E+08 1.23E+08 - - - 2.1959 0.9955 230117_WJC_METTL3_WT_vs_EV_F06.15529.15529.2 0.217 16-Jul K.FVPLLPGNR.S sp|P78527|PRKDC_HUMAN 1 1011.5866 1.06 48653 15529 2 1011.588552 506.8006 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3216.2 - 1.01E+06 - - - 1.9781 - 1.273 0.189 - 171.3 1 2 0 0.002 9 0 0 0 1.19E+08 1.13E+08 - - - 1.1346 0.9192 230117_WJC_METTL3_WT_vs_EV_F06.15543.15543.2 0.00744 18-Aug K.LLHHLSDLAL.T "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1130.6448 - 48661 15543 2 1130.646595 566.3297 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3217.7 - 484487 - - - 1.5929 - 1.241 0.359 - 129.7 1 1 0 0.0018 10 0 0 0 - - - - - 2.2947 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.15547.15547.2 0.613 14-Jun R.LLFGPTVR.L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 901.5385 0.86 48663 15547 2 901.539131 451.7765 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3218.2 - 5.94E+06 - - - 0.6578 - 1.26 0.195 - 106.3 1 2 0 0.0006 8 0 0 0 1.52E+08 1.77E+08 - - - 1.1781 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.15550.15550.2 0.0121 22-Sep K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.22 48665 15550 2 1287.7593 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3218.5 - 682137 - - - 1.1159 - 1.56 0.223 - 144.9 1 2 0 0.0014 12 0 0 0 7.88E+07 6.45E+07 - - - 1.8577 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.15554.15554.2 0.0231 16-Sep K.LLPDTILEK[136.11].L "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1048.626 0.72 48667 15554 2 1048.628123 525.3203 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 4.37 3218.9 - 1.03E+06 - - - 2.0608 - 1.584 0.217 - 212.8 1 2 0 0.0022 9 0 0 0 1.63E+08 2.28E+08 - - - 1.9738 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.15555.15555.2 0.0233 16-Aug K.LLPDTILEK.L "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1040.6118 0.73 48668 15555 2 1040.611739 521.3132 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 4.37 3219.1 - 935894 - - - -0.0221 - 1.459 0.323 - 139.5 1 2 0 0 9 0 0 0 1.63E+08 2.25E+08 - - - 2.5195 0.9919 230117_WJC_METTL3_WT_vs_EV_F06.15565.15565.2 0.105 14-Aug K.YYVLNALK.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 982.5488 2.36 48671 15565 2 982.548883 492.2817 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.5 3220.5 - 4.83E+06 - - - 0.117 - 1.143 0.191 - 157.1 1 2 0 0.0001 8 0 0 0 2.97E+08 1.26E+08 - - - 0.8548 1 230117_WJC_METTL3_WT_vs_EV_F06.15576.15576.2 7.30E-06 13/20 K.WEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1215.6288 0.91 48676 15576 2 1215.630468 608.8217 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3221.8 - 1.67E+06 - - - 1.3647 - 2.145 0.56 - 374 1 2 0 0.0017 11 0 0 0 1.05E+08 1.16E+08 - - - 5.2411 1 230117_WJC_METTL3_WT_vs_EV_F06.15580.15580.2 5.52E-07 16-Oct K.YMTDGMLLR[166.11].E "sp|Q14562|DHX8_HUMAN,sp|O60231|DHX16_HUMAN,sp|O43143|DHX15_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|F5H658|F5H658_HUMAN" 5 1108.5285 0.94 48678 15580 2 1108.529693 555.2715 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 5.84 3222.3 - 1.35E+06 - - - 1.115 - 1.941 0.652 - 346.3 1 2 0 0.0012 9 0 0 0 5.79E+07 6.14E+07 - - - 5.775 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15582.15582.2 0.000299 18-Oct K.LLANMVYQYK.G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1241.6478 1.83 48680 15582 2 1241.651887 621.8312 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3222.5 - 283471 - - - 3.2674 - 1.916 0.474 - 297.4 1 2 0 0.0041 10 0 0 0 3.88E+07 2.12E+07 - - - 4.3557 1 230117_WJC_METTL3_WT_vs_EV_F06.15590.15590.2 6.25E-05 18-Nov K.LLANMVYQYK[136.11].G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1249.662 1.83 48685 15590 2 1249.663355 625.8383 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3223.5 - 556697 - - - 1.0603 - 2.051 0.482 - 429.4 1 2 0 0.0013 10 0 0 0 3.88E+07 2.12E+07 - - - 4.6057 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15597.15597.2 0.00107 16-Aug K.YMTDGMLLR.E "sp|Q14562|DHX8_HUMAN,sp|O60231|DHX16_HUMAN,sp|O43143|DHX15_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|F5H658|F5H658_HUMAN" 5 1098.5202 0.96 48689 15597 2 1098.521497 550.2674 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 5.84 3224.3 - 1.92E+06 - - - 1.1925 - 1.391 0.417 - 169.8 1 2 0 0.0013 9 0 0 0 5.75E+07 5.96E+07 - - - 3.0753 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.15599.15599.2 0.0106 14-Jul R.AFLLDPDR.C sp|Q9BTY7|HGH1_HUMAN 1 945.492 1.13 48691 15599 2 945.490965 473.7533 Protein HGH1 homolog OS=Homo sapiens OX=9606 GN=HGH1 PE=1 SV=1 4.21 3224.6 - 353414 - - - -1.0756 - 1.402 0.329 - 174 1 2 0 -0.001 8 0 0 0 1.69E+07 1.49E+07 - - - 2.4898 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.15604.15604.2 0.0102 16-Aug R.LFEGNALLR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1031.5764 0.86 48694 15604 2 1031.578667 516.7955 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3225.1 - 4.48E+06 - - - 2.217 - 1.681 0.434 - 228.2 1 2 0 0.0023 9 0 0 0 1.50E+09 1.73E+09 - - - 3.7484 0.9941 230117_WJC_METTL3_WT_vs_EV_F06.15609.15609.2 1.05 14-Jul K.MLLSLPEK.V "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 929.5256 1.04 48699 15609 2 929.525933 465.7701 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 5.75 3225.6 - 545410 - - - 0.369 - 1.415 0.124 - 151.6 1 2 0 0.0003 8 0 0 0 2.43E+07 2.34E+07 - - - 1.0037 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.15612.15612.2 0.00742 16-Jul R.LFEGNALLR[166.11].R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1041.5847 0.86 48700 15612 2 1041.582829 521.7996 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3225.9 - 1.34E+07 - - - -1.7483 - 1.505 0.399 - 119.3 1 2 0 -0.0018 9 0 0 0 1.50E+09 1.74E+09 - - - 3.1701 0.999 230117_WJC_METTL3_WT_vs_EV_F06.15613.15613.2 0.0234 16-Aug R.VLGMTLIQK.C sp|Q04760|LGUL_HUMAN 1 1001.5943 1.25 48701 15613 2 1001.596603 501.8044 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3226 - 1.96E+06 - - - 2.2614 - 1.847 0.245 - 144.6 1 2 0 0.0023 9 0 0 0 5.02E+07 4.01E+07 - - - 2.6249 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.15614.15614.2 0.0182 16-Aug R.VLGMTLIQK[136.11].C sp|Q04760|LGUL_HUMAN 1 1009.6085 1.25 48702 15614 2 1009.610605 505.8115 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3226.1 - 2.06E+06 - - - 2.0473 - 1.495 0.227 - 154.6 1 2 0 0.0021 9 0 0 0 5.02E+07 4.01E+07 - - - 1.8803 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.15615.15615.2 0.293 14-Jul K.MLLSLPEK[136.11].V "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 937.5398 1.05 48703 15615 2 937.543276 469.7772 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 5.75 3226.2 - 897316 - - - 3.7182 - 1.553 0.295 - 161.3 1 2 0 0.0035 8 0 0 0 2.46E+07 2.34E+07 - - - 2.5464 0.9931 230117_WJC_METTL3_WT_vs_EV_F06.15617.15617.2 0.187 12-Jun R.GFFNGLR[166.11].T "sp|Q9Y394|DHRS7_HUMAN,tr|H0YJ66|H0YJ66_HUMAN,tr|H0YJE4|H0YJE4_HUMAN,tr|H0YJR8|H0YJR8_HUMAN" 4 819.4267 1.21 48705 15617 2 819.428569 410.7206 Dehydrogenase\reductase SDR family member 7 OS=Homo sapiens OX=9606 GN=DHRS7 PE=1 SV=1 9.75 3226.5 - 559652 - - - 2.2894 - 1.333 0.128 - 124.1 1 2 0 0.0019 7 0 0 0 1.21E+07 1.00E+07 - - - 0.8966 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.15621.15621.2 0.419 14-Aug K.VFNLGVYR[166.11].R "sp|O60825|F262_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN" 2 976.537 0.53 48707 15621 2 976.536549 489.2758 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 8.72 3227 - 847454 - - - -0.4321 - 1.756 0.176 - 222.1 1 2 0 -0.0004 8 0 0 0 3.82E+07 7.19E+07 - - - 2.0389 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.15623.15623.2 3.94 14-Sep R.SLVSGLIR[166.11].L sp|Q92616|GCN1_HUMAN 1 853.5261 1.07 48709 15623 2 853.52789 427.7703 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.47 3227.2 - 1.88E+06 - - - 2.13 - 1.676 0.131 - 294.3 1 2 0 0.0018 8 0 0 0 6.25E+07 5.83E+07 - - - 1.5655 0.9934 230117_WJC_METTL3_WT_vs_EV_F06.15624.15624.2 0.537 16-Jul R.VPLDPLIGK.N sp|P53384|NUBP1_HUMAN 1 950.5801 1.04 48710 15624 2 950.582001 476.2973 Cytosolic Fe-S cluster assembly factor NUBP1 OS=Homo sapiens OX=9606 GN=NUBP1 PE=1 SV=2 5.81 3227.4 - 1.51E+06 - - - 2.0335 - 1.359 0.144 - 154.7 2 2 0 0.0019 9 0 0 0 3.59E+07 3.47E+07 - - - 0.8569 0.8928 230117_WJC_METTL3_WT_vs_EV_F06.15625.15625.2 0.352 12-Aug L.FGDLLLK[136.11].Q "sp|Q15147|PLCB4_HUMAN,sp|Q6P2Q9|PRP8_HUMAN,tr|A0A7P0MRI8|A0A7P0MRI8_HUMAN" 3 812.4887 1.26 48711 15625 2 812.490549 407.2516 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4 PE=1 SV=3" 5.84 3227.4 - 1.01E+06 - - - 2.2253 - 1.667 0.203 - 144.4 1 1 0 0.0018 7 0 0 0 2.35E+08 1.86E+08 - - - 2.159 0.9752 230117_WJC_METTL3_WT_vs_EV_F06.15630.15630.2 3.26 16-Jul R.AIEQLAAMD.- "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 3 960.4586 - 48714 15630 2 960.460159 481.2366 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.03 3228.1 - 597357 - - - 1.5888 - 1.172 0.05 - 100.3 1 2 0 0.0015 9 0 0 0 - - - - - -0.131 0.9301 230117_WJC_METTL3_WT_vs_EV_F06.15634.15634.2 0.473 14-Jun R.NLEIQSWR[166.11].S "sp|O94823|AT10B_HUMAN,tr|A0A2R8YDI5|A0A2R8YDI5_HUMAN" 2 1054.5435 0.92 48716 15634 2 1054.54221 528.279 Phospholipid-transporting ATPase VB OS=Homo sapiens OX=9606 GN=ATP10B PE=1 SV=2 6 3228.6 - 639307 - - - -1.2356 - 1.27 0.019 - 102.3 1 2 0 -0.0013 8 0 0 0 3.43E+07 3.72E+07 - - - -0.0982 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.15639.15639.2 0.012 14-Aug K.VFNLGVYR.R "sp|O60825|F262_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN" 2 966.5287 0.54 48719 15639 2 966.532183 484.2716 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 8.72 3229.1 - 1.08E+06 - - - 3.6026 - 1.601 0.277 - 229.9 1 2 0 0.0035 8 0 0 0 3.89E+07 7.22E+07 - - - 2.5052 0.999 230117_WJC_METTL3_WT_vs_EV_F06.15641.15641.2 8.05E-05 20-Nov R.VIGTLLGTVDK[136.11].H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1122.674 1.09 48721 15641 2 1122.678524 562.3443 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3229.3 - 1.19E+06 - - - 4.0519 - 1.905 0.487 - 239.9 1 2 0 0.0045 11 0 0 0 1.29E+08 1.18E+08 - - - 4.38 0.997 230117_WJC_METTL3_WT_vs_EV_F06.15642.15642.2 0.000131 20-Oct R.VIGTLLGTVDK.H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1114.6598 1.09 48722 15642 2 1114.665746 558.3372 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3229.5 - 912576 - - - 5.3568 - 1.803 0.437 - 196.3 1 2 0 0.006 11 0 0 0 1.29E+08 1.18E+08 - - - 3.8614 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.15643.15643.2 0.00776 14-Aug R.IAVPVLVR.D sp|P52952|NKX25_HUMAN 1 865.5749 1.89 48723 15643 2 865.575764 433.7947 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 9.75 3229.6 - 796347 - - - 0.9716 - 1.665 0.367 - 218.7 1 2 0 0.0008 8 0 0 0 3.62E+07 1.91E+07 - - - 3.289 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.15644.15644.2 0.138 18-Oct K.LIESAEELIR[166.11].D "sp|Q13217|DNJC3_HUMAN,tr|X6R9L0|X6R9L0_HUMAN" 2 1181.6531 1.49 48724 15644 2 1181.65656 591.8338 DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1 4.25 3229.7 - 632979 - - - 2.9086 - 1.889 0.239 - 265.5 1 2 0 0.0034 10 0 0 0 1.23E+07 8.23E+06 - - - 2.5806 1 230117_WJC_METTL3_WT_vs_EV_F06.15648.15648.2 3.61E-05 14-Sep K.FVADGIFK[136.11].A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 903.4946 1.76 48726 15648 2 903.495374 452.7546 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3230.3 - 5.98E+07 - - - 0.9076 - 1.961 0.478 - 198.3 1 2 0 0.0008 8 0 0 0 4.31E+09 2.45E+09 - - - 4.6024 0.8954 230117_WJC_METTL3_WT_vs_EV_F06.15649.15649.2 0.317 12-Sep L.FGDLLLK.Q "sp|Q15147|PLCB4_HUMAN,sp|Q6P2Q9|PRP8_HUMAN,tr|A0A7P0MRI8|A0A7P0MRI8_HUMAN" 3 804.4745 1.26 48727 15649 2 804.475009 403.2445 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4 PE=1 SV=3" 5.84 3230.3 - 4.80E+06 - - - 0.5817 - 1.627 0.209 - 208 1 1 0 0.0005 7 0 0 0 2.31E+08 1.84E+08 - - - 2.1268 0.9739 230117_WJC_METTL3_WT_vs_EV_F06.15650.15650.2 1.48 12-May K.LVIDVIR[166.11].Y "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 836.5359 1.36 48728 15650 2 836.536256 419.2752 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.84 3230.4 - 4.08E+06 - - - 0.4148 - 1.148 0.106 - 73.5 5 2 0 0.0003 7 0 0 0 2.15E+08 1.58E+08 - - - -0.0511 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.15652.15652.2 0.153 12-Aug R.ITILLPK.R "sp|Q9BT43|RPC7L_HUMAN,tr|A6NGX6|A6NGX6_HUMAN,tr|A0A0D9SG24|A0A0D9SG24_HUMAN" 3 796.5422 1.91 48730 15652 2 796.543424 399.2784 DNA-directed RNA polymerase III subunit RPC7-like OS=Homo sapiens OX=9606 GN=POLR3GL PE=1 SV=1 8.75 3230.5 - 716699 - - - 1.504 - 1.765 0.27 - 145 1 2 0 0.0012 7 0 0 0 2.57E+07 1.35E+07 - - - 2.8351 0.9418 230117_WJC_METTL3_WT_vs_EV_F06.15653.15653.2 1.99 12-Jul R.QATFLFR.R "sp|Q96QD9|UIF_HUMAN,tr|H9KVC6|H9KVC6_HUMAN" 2 881.4759 1.09 48731 15653 2 881.478944 441.7452 UAP56-interacting factor OS=Homo sapiens OX=9606 GN=FYTTD1 PE=1 SV=3 9.75 3230.6 - 605827 - - - 3.4102 - 1.274 0.005 - 127.5 1 2 0 0.003 7 0 0 0 2.97E+07 2.72E+07 - - - -0.1557 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.15654.15654.2 0.0168 18-Jul R.LIYTAGGYFR.Q sp|Q14145|KEAP1_HUMAN 1 1159.6026 2.17 48732 15654 2 1159.604555 580.8086 Kelch-like ECH-associated protein 1 OS=Homo sapiens OX=9606 GN=KEAP1 PE=1 SV=2 8.59 3230.8 - 588166 - - - 1.6902 - 1.457 0.189 - 147.9 1 2 0 0.002 10 0 0 0 1.13E+07 5.19E+06 - - - 1.4869 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.15655.15655.2 0.00586 16-Sep R.LWGEPVNLR.E "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 1082.5873 1.3 48733 15655 2 1082.589433 542.3009 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 6 3230.9 - 533735 - - - 1.9897 - 1.818 0.12 - 269.5 1 2 0 0.0022 9 0 0 0 1.74E+07 1.33E+07 - - - 1.6559 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.15662.15662.2 1.65 14-Aug R.SLVSGLIR.L sp|Q92616|GCN1_HUMAN 1 843.5178 1.08 48738 15662 2 843.519025 422.7662 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.47 3231.7 - 5.35E+06 - - - 1.4499 - 1.452 0.187 - 249.6 1 2 0 0.0012 8 0 0 0 6.27E+07 5.83E+07 - - - 1.5466 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.15664.15664.2 0.0427 14-Jul R.FVDGLTFK.V "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 925.4909 0.97 48740 15664 2 925.49144 463.7527 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.84 3231.8 - 1.62E+06 - - - 0.5629 - 1.334 0.321 - 128.1 1 2 0 0.0005 8 0 0 0 2.14E+07 2.22E+07 - - - 2.2809 0.986 230117_WJC_METTL3_WT_vs_EV_F06.15665.15665.2 0.371 14-Aug K.NLYIISVK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 956.5786 1.29 48741 15665 2 956.58105 479.2966 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3232 - 1.21E+06 - - - 2.5424 - 1.412 0.053 - 177.7 1 2 0 0.0024 8 0 0 0 4.48E+09 3.46E+09 - - - 0.4722 0.976 230117_WJC_METTL3_WT_vs_EV_F06.15666.15666.2 2.83 14-Oct R.IAVPVLVR[166.11].D sp|P52952|NKX25_HUMAN 1 875.5832 1.92 48742 15666 2 875.585857 438.7989 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 9.75 3232.1 - 1.02E+06 - - - 3.0425 - 1.375 0.04 - 382.8 1 2 0 0.0027 8 0 0 0 3.66E+07 1.91E+07 - - - 0.296 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.15672.15672.2 0.00431 16-Sep R.AMAVLESLR[166.11].V "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN" 4 998.5458 0.76 48746 15672 2 998.546825 500.2802 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.05 3232.7 - 1.39E+06 - - - 1.0045 - 1.715 0.3 - 302.2 1 2 0 0.001 9 0 0 0 3.34E+07 4.37E+07 - - - 2.817 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15673.15673.2 0.0149 14-Jul R.FVDGLTFK[136.11].V "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 933.5051 0.97 48747 15673 2 933.505302 467.7598 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.84 3232.8 - 1.12E+06 - - - 0.196 - 1.453 0.427 - 118.5 1 2 0 0.0002 8 0 0 0 2.13E+07 2.20E+07 - - - 3.3216 0.8461 230117_WJC_METTL3_WT_vs_EV_F06.15678.15678.2 0.00249 18-Oct R.PADVIFATVR.E sp|P33993|MCM7_HUMAN 1 1087.6026 3.65 48751 15678 2 1087.600896 544.8086 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 6.27 3233.4 - 454628 - - - -1.5622 - 1.992 0.276 - 318 1 1 0 -0.0017 10 0 0 0 1.35E+07 3.70E+06 - - - 3.0026 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.15680.15680.2 0.0464 12-Jul K.FVSELWK[136.11].D sp|P35579|MYH9_HUMAN 1 915.4946 0.63 48752 15680 2 915.494364 458.7546 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6 3233.6 - 7.58E+06 - - - -0.2075 - 1.566 0.314 - 136.3 1 2 0 -0.0002 7 0 0 0 1.54E+08 2.47E+08 - - - 2.7813 0.9617 230117_WJC_METTL3_WT_vs_EV_F06.15682.15682.2 1.46 16-May R.FLPSPVVIK[136.11].K "sp|Q13618|CUL3_HUMAN,tr|H7C399|H7C399_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 3 1006.6307 0.6 48754 15682 2 1006.63241 504.3226 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 8.75 3233.7 - 3.12E+06 - - - 1.7444 - 1.02 0.097 - 72.6 3 2 0 0.0018 9 0 0 0 8.58E+07 1.44E+08 - - - -0.399 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.15684.15684.2 0.0114 14-Jul R.LFC[160.03]VGFTK.K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 970.4946 0.82 48756 15684 2 970.497217 486.2546 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.22 3233.9 - 1.10E+06 - - - 2.6718 - 1.418 0.259 - 145.8 1 2 0 0.0026 8 0 0 0 5.18E+08 6.28E+08 - - - 2.0065 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.15687.15687.2 0.000661 20-Aug R.LFSGDVVLTAR.D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1176.6503 0.96 48759 15687 2 1176.652591 589.3324 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3234.2 - 402799 - - - 1.97 - 1.955 0.399 - 178.4 1 2 0 0.0023 11 0 0 0 2.44E+08 2.53E+08 - - - 3.8009 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.15690.15690.2 0.00611 14-Jul R.LFC[160.03]VGFTK[136.11].K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 978.5088 0.82 48760 15690 2 978.510932 490.2617 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.22 3234.6 - 4.02E+06 - - - 2.1543 - 1.522 0.422 - 150 1 2 0 0.0021 8 0 0 0 5.18E+08 6.28E+08 - - - 3.424 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15692.15692.2 0.0114 14-Sep K.TAVLTLIR.E "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 8 885.5648 1.24 48762 15692 2 885.566523 443.7897 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 9.41 3234.8 - 1.52E+06 - - - 1.9987 - 1.975 0.277 - 392.9 1 2 0 0.0018 8 0 0 0 1.95E+08 1.58E+08 - - - 3.1389 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.15693.15693.2 0.318 14-Jul R.LLPSLIGR.H "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 4 867.5542 0.75 48763 15693 2 867.553774 434.7844 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 9.75 3234.9 - 1.19E+06 - - - -0.4772 - 1.279 0.304 - 164 1 2 0 -0.0004 8 0 0 0 9.05E+07 1.20E+08 - - - 2.0284 1 230117_WJC_METTL3_WT_vs_EV_F06.15694.15694.2 1.46E-05 20-Nov R.LFSGDVVLTAR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1186.6585 0.96 48764 15694 2 1186.660482 594.3365 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3235.1 - 644470 - - - 1.634 - 2.093 0.532 - 359.6 1 2 0 0.0019 11 0 0 0 2.44E+08 2.53E+08 - - - 4.9678 0.9934 230117_WJC_METTL3_WT_vs_EV_F06.15695.15695.2 0.0115 18-Aug R.IVLVDDSIVR[166.11].G sp|Q06203|PUR1_HUMAN 1 1137.6633 1.92 48765 15695 2 1137.669206 569.8389 Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1 4.21 3235.2 - 285782 - - - 5.1966 - 1.455 0.339 - 119.4 1 2 0 0.0059 10 0 0 0 5.45E+07 2.84E+07 - - - 2.5898 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.15696.15696.2 0.0415 16-Jun K.LDELYGTWR[166.11].K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1161.5694 4.03 48766 15696 2 1161.569284 581.792 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 4.37 3235.3 - 325404 - - - -0.0947 - 1.522 0.269 - 87.5 1 2 0 -0.0001 9 0 0 0 4.08E+07 1.01E+07 - - - 2.243 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.15700.15700.2 0.0825 18-Jul R.IVLVDDSIVR.G sp|Q06203|PUR1_HUMAN 1 1127.655 1.91 48768 15700 2 1127.656301 564.8348 Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1 4.21 3235.8 - 602461 - - - 1.1324 - 1.473 0.249 - 107 1 2 0 0.0013 10 0 0 0 5.45E+07 2.84E+07 - - - 1.9608 0.9791 230117_WJC_METTL3_WT_vs_EV_F06.15710.15710.2 0.141 14-Jun K.AVIELLEK[136.11].S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|H0Y327|H0Y327_HUMAN,tr|Q5JYA8|Q5JYA8_HUMAN,tr|Q5JYA3|Q5JYA3_HUMAN" 6 921.5626 2.81 48774 15710 2 921.562528 461.7886 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.53 3237.1 - 833332 - - - -0.115 - 1.337 0.048 - 75.2 1 2 0 -0.0001 8 0 0 0 8.36E+07 2.97E+07 - - - 0.2714 0.9727 230117_WJC_METTL3_WT_vs_EV_F06.15716.15716.2 0.431 14-Aug R.TVETLLLR.F "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 6 943.5702 0.51 48777 15716 2 943.5738 472.7924 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 5.66 3237.8 - 2.27E+06 - - - 3.7814 - 1.392 0.067 - 170.1 1 2 0 0.0036 8 0 0 0 1.19E+08 2.35E+08 - - - 0.5322 1 230117_WJC_METTL3_WT_vs_EV_F06.15719.15719.2 7.03E-06 26-Oct K.VLEQLTGQTPVFSK[136.11].A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1553.8545 1.4 48780 15719 2 1553.853407 777.9345 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3238.1 - 0 - - - -0.677 - 2.111 0.499 - 256.8 1 2 0 -0.0011 14 0 0 0 5.95E+06 4.24E+06 - - - 4.6012 0.9781 230117_WJC_METTL3_WT_vs_EV_F06.15722.15722.2 0.0276 16-Aug R.FFMGNQVLK.V sp|P13010|XRCC5_HUMAN 1 1082.5583 0.8 48781 15722 2 1082.553458 542.2864 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3238.5 - 627343 - - - -4.4607 - 1.406 0.33 - 129.3 1 2 0 -0.0048 9 0 0 0 8.97E+07 1.12E+08 - - - 2.4627 0.9892 230117_WJC_METTL3_WT_vs_EV_F06.15723.15723.2 0.199 14-May K.ILIDSIYK.V "sp|Q4KWH8|PLCH1_HUMAN,tr|A0A2U3TZV8|A0A2U3TZV8_HUMAN" 2 963.5641 35.17 48782 15723 2 963.562815 482.7893 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 OS=Homo sapiens OX=9606 GN=PLCH1 PE=1 SV=1" 5.83 3238.6 - 521827 - - - -1.317 - 1.202 0.268 - 50.8 4 2 0 -0.0013 8 0 0 0 9.40E+07 2.67E+06 - - - 1.306 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.15724.15724.2 0.00473 18-Aug R.LVPLQEEIYR.K "sp|Q2NKX8|ERC6L_HUMAN,tr|B5MDQ0|B5MDQ0_HUMAN" 2 1258.6921 3.65 48783 15724 2 1258.694155 630.3533 DNA excision repair protein ERCC-6-like OS=Homo sapiens OX=9606 GN=ERCC6L PE=1 SV=1 4.53 3238.8 - 159771 - - - 1.6025 - 1.642 0.306 - 312.6 1 2 0 0.002 10 0 0 0 1.13E+07 3.08E+06 - - - 2.6847 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.15729.15729.2 0.00166 22-Oct R.VLVTGATGLLGR.A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1155.6976 1.4 48785 15729 2 1155.702147 578.8561 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3239.5 - 527107 - - - 3.9708 - 1.643 0.462 - 249.8 1 2 0 0.0046 12 0 0 0 2.67E+07 1.90E+07 - - - 3.7583 0.997 230117_WJC_METTL3_WT_vs_EV_F06.15730.15730.2 0.0367 14-Jun R.ELYPVEFR.N "sp|Q5BJF2|SGMR2_HUMAN,tr|J3KT68|J3KT68_HUMAN" 2 1051.5338 1.35 48786 15730 2 1051.533704 526.7742 Sigma intracellular receptor 2 OS=Homo sapiens OX=9606 GN=TMEM97 PE=1 SV=1 4.53 3239.6 - 398712 - - - -0.135 - 1.303 0.262 - 132.4 1 2 0 -0.0001 8 0 0 0 3.24E+07 2.41E+07 - - - 1.7743 1 230117_WJC_METTL3_WT_vs_EV_F06.15736.15736.2 0.00125 13/26 K.VLEQLTGQTPVFSK.A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1545.8403 1.4 48789 15736 2 1545.844805 773.9274 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3240.4 - 156198 - - - 2.9408 - 2.724 0.534 - 392.1 1 2 0 0.0045 14 0 0 0 5.95E+06 4.24E+06 - - - 5.4984 0.995 230117_WJC_METTL3_WT_vs_EV_F06.15741.15741.2 1.17 16-Aug K.EALEAVLIK.G "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 984.5855 1.68 48792 15741 2 984.585705 493.3001 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 4.53 3241 - 1.32E+06 - - - 0.1595 - 1.488 0.137 - 143.2 1 2 0 0.0002 9 0 0 0 3.04E+07 1.81E+07 - - - 1.2026 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.15742.15742.2 0.00676 22-Sep R.VLVTGATGLLGR[166.11].A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1165.7058 1.4 48793 15742 2 1165.707077 583.8602 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3241.1 - 798484 - - - 1.0715 - 1.892 0.416 - 207.3 1 2 0 0.0012 12 0 0 0 2.67E+07 1.90E+07 - - - 3.7909 0.9737 230117_WJC_METTL3_WT_vs_EV_F06.15744.15744.2 1.1 16-Aug K.LIPPQDILR[166.11].D sp|Q96A65|EXOC4_HUMAN 1 1073.6472 1.62 48795 15744 2 1073.648442 537.8309 Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1 5.84 3241.4 - 358037 - - - 1.1102 - 1.197 0.036 - 145.2 1 2 0 0.0012 9 0 0 0 2.40E+07 1.48E+07 - - - -0.1733 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15751.15751.2 0.00141 16-Sep R.FFMGNQVLK[136.11].V sp|P13010|XRCC5_HUMAN 1 1090.5725 0.8 48799 15751 2 1090.574647 546.2935 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3242.3 - 1.85E+06 - - - 1.9806 - 1.45 0.392 - 154 1 2 0 0.0022 9 0 0 0 9.01E+07 1.12E+08 - - - 3.0106 1 230117_WJC_METTL3_WT_vs_EV_F06.15762.15762.3 0.000673 18/64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 19.54 48805 15762 3 1786.986135 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3243.6 - 511810 - - - 1.8103 - 3.552 0.513 - 351.4 1 2 0 0.0032 17 0 0 0 3.44E+07 1.76E+06 - - - 7.4607 0.8995 230117_WJC_METTL3_WT_vs_EV_F06.15763.15763.2 0.124 14-Sep N.IIEEALIR[166.11].R "sp|Q96EQ8|RN125_HUMAN,sp|P78527|PRKDC_HUMAN" 2 965.5785 14.62 48806 15763 2 965.57735 483.7965 E3 ubiquitin-protein ligase RNF125 OS=Homo sapiens OX=9606 GN=RNF125 PE=1 SV=4 4.53 3243.8 - 429441 - - - -1.1931 - 1.906 0.32 - 204.9 1 1 0 -0.0012 8 0 0 0 1.85E+09 1.27E+08 - - - 3.3495 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.15766.15766.2 0.289 14-Jun K.EMVELPLR.H "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN" 10 985.5267 0.85 48807 15766 2 985.528643 493.7706 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.53 3244.2 - 594965 - - - 2.0192 - 1.38 0.185 - 87.2 1 2 0 0.002 8 0 0 0 1.92E+07 2.27E+07 - - - 1.3782 0.9903 230117_WJC_METTL3_WT_vs_EV_F06.15771.15771.2 0.25 14-May K.EMVELPLR[166.11].H "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN" 10 995.5349 0.85 48810 15771 2 995.53889 498.7747 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.53 3244.8 - 839849 - - - 3.9848 - 1.272 0.226 - 75.4 1 2 0 0.004 8 0 0 0 1.92E+07 2.27E+07 - - - 1.4346 0.9943 230117_WJC_METTL3_WT_vs_EV_F06.15775.15775.2 0.315 12-Jun K.AFLFVNK.G sp|Q8N0X7|SPART_HUMAN 1 837.4749 1.51 48812 15775 2 837.477835 419.7447 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3245.4 - 8.73E+06 - - - 3.5344 - 1.209 0.269 - 167.7 1 2 0 0.003 7 0 0 0 3.04E+08 2.02E+08 - - - 1.6283 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.15777.15777.2 0.0854 12-Jun K.AFLFVNK[136.11].G sp|Q8N0X7|SPART_HUMAN 1 845.4891 1.5 48814 15777 2 845.4904 423.7518 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3245.5 - 5.34E+06 - - - 1.5671 - 1.191 0.265 - 163.6 1 2 0 0.0013 7 0 0 0 3.06E+08 2.03E+08 - - - 1.5517 0.9882 230117_WJC_METTL3_WT_vs_EV_F06.15778.15778.2 0.663 12-Jun K.SIELFYK[136.11].F sp|P78527|PRKDC_HUMAN 1 906.4942 0.83 48815 15778 2 906.495969 454.2544 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.72 3245.6 - 1.34E+06 - - - 1.9294 - 1.085 0.151 - 130.6 1 2 0 0.0017 7 0 0 0 2.62E+07 3.17E+07 - - - 0.4142 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.15779.15779.2 0.00743 18-Sep R.GLIENPALLR[166.11].W sp|O95168|NDUB4_HUMAN 1 1104.6531 1.23 48816 15779 2 1104.655995 553.3338 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3 6 3245.7 - 624483 - - - 2.6533 - 2.07 0.298 - 214.2 1 2 0 0.0029 10 0 0 0 4.56E+07 3.71E+07 - - - 3.2719 0.9939 230117_WJC_METTL3_WT_vs_EV_F06.15783.15783.2 0.0263 16-Sep R.ILPQDVILK[136.11].F "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1045.6627 1.13 48817 15783 2 1045.665094 523.8386 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.84 3246.3 - 922274 - - - 2.3067 - 1.482 0.11 - 162.5 1 2 0 0.0024 9 0 0 0 3.12E+07 2.77E+07 - - - 0.9908 0.9964 230117_WJC_METTL3_WT_vs_EV_F06.15784.15784.2 0.0231 22-Aug K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.21 48818 15784 2 1277.753594 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3246.4 - 565722 - - - 3.1313 - 1.528 0.224 - 136.5 1 2 0 0.004 12 0 0 0 3.84E+07 3.17E+07 - - - 1.8097 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.15786.15786.3 0.0643 Nov-64 R.IINEPTAAAIAYGLDK[136.11]K[136.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1803.0113 31.53 48820 15786 3 1803.014381 602.011 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3246.6 - 252749 - - - 1.7088 - 2.112 0.338 - 125 1 2 0 0.0031 17 0 0 0 7.54E+07 2.39E+06 - - - 4.1963 0.9868 230117_WJC_METTL3_WT_vs_EV_F06.15792.15792.2 0.174 14-Jun K.FVIPLHSA.- sp|Q96F86|EDC3_HUMAN 1 882.4963 - 48824 15792 2 882.499155 442.2554 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 6.74 3247.4 - 1.97E+06 - - - 3.1909 - 1.258 0.143 - 136.6 1 2 0 0.0028 8 0 0 0 - - - - - 0.7885 0.9951 230117_WJC_METTL3_WT_vs_EV_F06.15794.15794.2 0.211 20-Jun K.MVLSGC[160.03]AIIVR[166.11].G sp|Q7KZF4|SND1_HUMAN 1 1227.6707 1.43 48826 15794 2 1227.672772 614.8426 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 8 3247.6 - 137155 - - - 1.6837 - 1.31 0.168 - 78.8 1 2 0 0.0021 11 0 0 0 2.57E+06 1.80E+06 - - - 1.0117 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.15803.15803.2 0.0673 18-Sep R.GLIENPALLR.W sp|O95168|NDUB4_HUMAN 1 1094.6448 1.23 48831 15803 2 1094.647594 548.3297 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3 6 3248.8 - 1.62E+06 - - - 2.5579 - 1.664 0.139 - 202.5 1 2 0 0.0028 10 0 0 0 4.56E+07 3.71E+07 - - - 1.4882 0.9407 230117_WJC_METTL3_WT_vs_EV_F06.15813.15813.2 4.66 14-Jun K.GLVAVGER.A "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 3 799.4552 1.23 48839 15813 2 799.457906 400.7349 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3249.9 - 987592 - - - 3.3823 - 1.21 0.07 - 86.6 5 2 0 0.0027 8 0 0 0 2.75E+07 2.23E+07 - - - -0.1802 0.9916 230117_WJC_METTL3_WT_vs_EV_F06.15814.15814.2 0.757 12-Jul R.VLQLFTR.L "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 875.5229 1.12 48840 15814 2 875.52437 438.7687 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 9.72 3250 - 429530 - - - 1.6927 - 1.338 0.088 - 118.2 1 2 0 0.0015 7 0 0 0 6.36E+07 5.69E+07 - - - 0.6131 0.9938 230117_WJC_METTL3_WT_vs_EV_F06.15815.15815.2 0.108 16-Jun R.YMVALQIAR[166.11].E sp|Q7KZ85|SPT6H_HUMAN 1 1073.5931 1.44 48841 15815 2 1073.593955 537.8038 Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2 8.75 3250.1 - 299322 - - - 0.7908 - 1.14 0.196 - 86.3 1 2 0 0.0008 9 0 0 0 5.09E+06 3.53E+06 - - - 0.8675 0.9969 230117_WJC_METTL3_WT_vs_EV_F06.15820.15820.2 0.0161 16-Sep R.ILPQDVILK.F "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1037.6485 0.95 48844 15820 2 1037.650925 519.8315 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.84 3250.7 - 1.39E+06 - - - 2.3544 - 1.407 0.208 - 197.9 1 2 0 0.0024 9 0 0 0 4.14E+07 4.35E+07 - - - 1.5644 0.9931 230117_WJC_METTL3_WT_vs_EV_F06.15822.15822.2 0.00883 14-Jul K.YFEYIMAK[136.11].E sp|P13674|P4HA1_HUMAN 1 1071.5191 2.42 48846 15822 2 1071.524615 536.7668 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3250.9 - 463681 - - - 5.1898 - 1.211 0.396 - 118.4 1 2 0 0.0056 8 0 0 0 7.34E+07 3.03E+07 - - - 2.5415 0.9145 230117_WJC_METTL3_WT_vs_EV_F06.15829.15829.2 0.0122 18-Oct H.ILSPWGAEVK[136.11].A "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1106.6215 0.84 48851 15829 2 1106.620548 554.318 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3251.7 - 2.17E+06 - - - -0.9018 - 1.804 0.359 - 236.1 1 1 0 -0.001 10 0 0 0 1.14E+08 1.36E+08 - - - 3.3391 0.9459 230117_WJC_METTL3_WT_vs_EV_F06.15830.15830.2 0.832 14-Aug N.IIEEALIR.R "sp|Q96EQ8|RN125_HUMAN,sp|P78527|PRKDC_HUMAN" 2 955.5702 14.71 48852 15830 2 955.571175 478.7924 E3 ubiquitin-protein ligase RNF125 OS=Homo sapiens OX=9606 GN=RNF125 PE=1 SV=4 4.53 3251.7 - 7.92E+06 - - - 0.9868 - 1.64 0.305 - 185.3 1 1 0 0.0009 8 0 0 0 1.85E+09 1.26E+08 - - - 2.7854 0.997 230117_WJC_METTL3_WT_vs_EV_F06.15832.15832.2 0.352 12-Aug R.VLQLFTR[166.11].L "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 885.5312 1.15 48854 15832 2 885.533234 443.7729 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 9.72 3251.9 - 1.15E+06 - - - 2.3444 - 1.518 0.164 - 189.8 1 2 0 0.0021 7 0 0 0 6.34E+07 5.54E+07 - - - 1.5742 0.9875 230117_WJC_METTL3_WT_vs_EV_F06.15834.15834.2 1.59 14-Jun R.VILLDVAR.G sp|Q9H2M9|RBGPR_HUMAN 1 897.5648 1.3 48856 15834 2 897.567133 449.7897 Rab3 GTPase-activating protein non-catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP2 PE=1 SV=1 5.81 3252.1 - 821758 - - - 2.6516 - 1.393 0.104 - 72.7 3 2 0 0.0024 8 0 0 0 1.94E+07 1.50E+07 - - - 0.5949 0.9898 230117_WJC_METTL3_WT_vs_EV_F06.15839.15839.2 0.0515 16-Aug R.VFNPYTEFK.E sp|Q96C19|EFHD2_HUMAN 1 1143.5601 1.49 48861 15839 2 1143.56509 572.7873 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 5.97 3252.7 - 272214 - - - 4.3977 - 1.227 0.27 - 173.1 1 2 0 0.005 9 0 0 0 3.52E+07 2.37E+07 - - - 1.6255 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.15845.15845.2 0.00236 14-Jul K.YFEYIMAK.E sp|P13674|P4HA1_HUMAN 1 1063.5049 2.43 48865 15845 2 1063.50449 532.7597 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3253.2 - 2.49E+06 - - - -0.3423 - 1.35 0.414 - 132.4 1 2 0 -0.0004 8 0 0 0 7.34E+07 3.02E+07 - - - 3.0038 0.9942 230117_WJC_METTL3_WT_vs_EV_F06.15849.15849.2 0.00154 16-Aug K.SMLLSAIGK[136.11].R "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 926.535 3.22 48869 15849 2 926.531826 464.2748 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.47 3253.7 - 656965 - - - -3.4678 - 1.607 0.402 - 135.1 1 2 0 -0.0032 9 0 0 0 5.90E+07 1.83E+07 - - - 3.3815 0.9636 230117_WJC_METTL3_WT_vs_EV_F06.15852.15852.2 1.91 14-Jul K.GFEYILAK.L "sp|Q9Y255|PRLD1_HUMAN,tr|H0YA79|H0YA79_HUMAN" 2 939.5066 0.83 48870 15852 2 939.509852 470.7606 "PRELI domain-containing protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=PRELID1 PE=1 SV=1" 6 3254.1 - 754052 - - - 3.4944 - 1.156 0.116 - 107.7 2 2 0 0.0033 8 0 0 0 7.19E+08 8.65E+08 - - - 0.1995 0.9846 230117_WJC_METTL3_WT_vs_EV_F06.15857.15857.2 0.29 14-Jun K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 2.12 48874 15857 2 895.483757 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3254.7 - 456830 - - - 3.8002 - 1.209 0.183 - 82.8 1 2 0 0.0034 8 0 0 0 2.81E+07 1.32E+07 - - - 0.964 0.9914 230117_WJC_METTL3_WT_vs_EV_F06.15859.15859.2 1.78 12-Jul K.ILIWSGR.F "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 843.4967 1.45 48875 15859 2 843.495551 422.7556 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 9.75 3254.9 - 1.46E+06 - - - -1.3302 - 1.367 0.199 - 166.9 1 2 0 -0.0011 7 0 0 0 1.28E+08 8.81E+07 - - - 1.501 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15864.15864.2 0.00448 16-Sep K.SMLLSAIGK.R "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 918.5208 2.76 48879 15864 2 918.521553 460.2677 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.47 3255.3 - 1.93E+06 - - - 0.7773 - 1.735 0.341 - 231.8 1 2 0 0.0007 9 0 0 0 4.89E+07 1.77E+07 - - - 3.1535 0.9255 230117_WJC_METTL3_WT_vs_EV_F06.15871.15871.2 11 16-May K.KDIFNEHLR[166.11].L "sp|O14686|KMT2D_HUMAN,tr|A0A804HHR9|A0A804HHR9_HUMAN" 2 1180.6228 - 48882 15871 2 1180.622008 591.3187 Histone-lysine N-methyltransferase 2D OS=Homo sapiens OX=9606 GN=KMT2D PE=1 SV=2 6.75 3256.2 - 324290 - - - -0.6929 - 1.23 0 - 83.8 1 2 0 -0.0008 9 0 0 0 - - - - - -0.3604 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.15874.15874.2 0.00925 18-Aug K.IGDLGLATLK.R "sp|Q9H4A3|WNK1_HUMAN,sp|Q96J92|WNK4_HUMAN,sp|Q9Y3S1|WNK2_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A6PVV2|A6PVV2_HUMAN,tr|K7ENT7|K7ENT7_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 9 999.5964 2.2 48884 15874 2 999.598819 500.8055 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 5.84 3256.5 - 2.23E+06 - - - 2.373 - 1.931 0.267 - 119.8 1 2 0 0.0024 10 0 0 0 1.13E+08 5.13E+07 - - - 2.8491 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.15879.15879.2 0.0669 14-Aug K.GIAYIEFK[136.11].T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 947.5208 0.83 48887 15879 2 947.521417 474.7677 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3257 - 4.82E+06 - - - 0.6839 - 1.361 0.254 - 213.7 1 2 0 0.0006 8 0 0 0 7.18E+08 8.65E+08 - - - 1.8464 0.9954 230117_WJC_METTL3_WT_vs_EV_F06.15880.15880.2 0.0279 18-Sep K.AFADSSYLLR[166.11].H "sp|Q9H5H4|ZN768_HUMAN,tr|H3BS42|H3BS42_HUMAN" 2 1151.585 0.74 48888 15880 2 1151.584139 576.7998 Zinc finger protein 768 OS=Homo sapiens OX=9606 GN=ZNF768 PE=1 SV=2 5.88 3257.1 - 1.11E+06 - - - -0.7859 - 1.234 0.285 - 169.6 1 2 0 -0.0009 10 0 0 0 2.16E+07 2.91E+07 - - - 1.7326 0.9709 230117_WJC_METTL3_WT_vs_EV_F06.15883.15883.2 3.01 12-Jun K.ILIWSGR[166.11].F "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 853.5049 1.44 48889 15883 2 853.505787 427.7597 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 9.75 3257.5 - 3.16E+06 - - - 0.9889 - 1.231 0.01 - 91 1 2 0 0.0008 7 0 0 0 1.27E+08 8.81E+07 - - - -0.2269 0.9941 230117_WJC_METTL3_WT_vs_EV_F06.15885.15885.2 0.174 12-Jun R.LYDGLFK.V "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 10 854.4538 2.04 48891 15885 2 854.453701 428.2342 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.83 3257.7 - 3.16E+06 - - - -0.1217 - 1.196 0.215 - 88.8 1 2 0 -0.0001 7 0 0 0 3.03E+08 1.48E+08 - - - 1.1961 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.15888.15888.2 0.00137 14-Aug R.GLVGIEFK.E sp|P15924|DESP_HUMAN 1 861.496 9.11 48893 15888 2 861.495605 431.7553 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 3258.1 - 973596 - - - -0.4631 - 1.599 0.272 - 246.4 1 2 0 -0.0004 8 0 0 0 2.44E+08 2.68E+07 - - - 2.4655 0.996 230117_WJC_METTL3_WT_vs_EV_F06.15899.15899.2 0.00332 16-Jul K.VLPVGVLYK.V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 986.6165 0.54 48900 15899 2 986.614235 494.3155 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3259.4 - 781020 - - - -2.2491 - 1.481 0.363 - 104.7 1 2 0 -0.0022 9 0 0 0 1.24E+08 2.29E+08 - - - 2.8576 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.15901.15901.2 0.0558 16-Aug R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 0.73 48901 15901 2 952.597354 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3259.6 - 1.95E+08 - - - 1.7174 - 1.339 0.249 - 217.6 1 2 0 0.0016 9 0 0 0 1.27E+10 1.74E+10 - - - 1.7241 0.9864 230117_WJC_METTL3_WT_vs_EV_F06.15908.15908.2 0.852 12-Jun R.LLLAFQK.K sp|Q14781|CBX2_HUMAN 1 831.5218 1.29 48905 15908 2 831.522471 416.7682 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.75 3260.4 - 1.36E+06 - - - 0.7769 - 1.258 0.073 - 96.7 1 2 0 0.0006 7 0 0 0 5.07E+07 3.92E+07 - - - 0.3072 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.15914.15914.2 0.000879 20-Nov R.ILMVGLDAAGK.T "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|F5H1V1|F5H1V1_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|F5H6T5|F5H6T5_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|F8WDB3|F8WDB3_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 11 1086.6107 1.68 48909 15914 2 1086.611178 544.3126 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3261 - 2.12E+06 - - - 0.4243 - 2.051 0.399 - 319.2 1 2 0 0.0005 11 0 0 0 2.44E+08 1.45E+08 - - - 3.9311 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.15922.15922.2 0.448 16-Sep R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 0.73 48914 15922 2 960.610091 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3262 - 1.45E+08 - - - 0.1801 - 1.843 0.234 - 262.1 1 2 0 0.0002 9 0 0 0 1.27E+10 1.74E+10 - - - 2.5381 0.9418 230117_WJC_METTL3_WT_vs_EV_F06.15927.15927.2 3.15 12-May R.LFFVGSR[166.11].E "sp|Q9UM01|YLAT1_HUMAN,sp|Q92536|YLAT2_HUMAN,sp|Q01650|LAT1_HUMAN,tr|H0YJ95|H0YJ95_HUMAN,tr|A0A0C4DGL4|A0A0C4DGL4_HUMAN,tr|G3V4Z6|G3V4Z6_HUMAN" 6 834.4627 0.86 48917 15927 2 834.461258 418.2386 Y+L amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A7 PE=1 SV=2 9.75 3262.5 - 734882 - - - -1.7808 - 1.241 0.127 - 86.7 8 2 0 -0.0015 7 0 0 0 3.06E+07 3.55E+07 - - - 0.2593 0.9909 230117_WJC_METTL3_WT_vs_EV_F06.15928.15928.2 1.74 12-Jun K.ILIEDWK[136.11].K "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A7I2V2T6|A0A7I2V2T6_HUMAN,tr|K7EPW7|K7EPW7_HUMAN" 4 923.5208 1.41 48918 15928 2 923.522392 462.7677 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 4.37 3262.7 - 598999 - - - 1.7574 - 1.314 0.089 - 90.3 1 2 0 0.0016 7 0 0 0 4.19E+07 2.97E+07 - - - 0.5631 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.15933.15933.2 0.00719 16-Sep R.LLLQLEATK.N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1027.6277 6.91 48921 15933 2 1027.625722 514.8211 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3263.3 - 876280 - - - -1.9706 - 1.933 0.348 - 213.1 1 2 0 -0.002 9 0 0 0 4.92E+08 7.12E+07 - - - 3.5174 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15938.15938.2 0.000897 18-Sep R.GYFEYIEENK.Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1290.5768 1.6 48924 15938 2 1290.576216 646.2957 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3263.9 - 329742 - - - -0.4781 - 1.928 0.429 - 176.3 1 2 0 -0.0006 10 0 0 0 1.11E+07 6.97E+06 - - - 4.0418 0.9798 230117_WJC_METTL3_WT_vs_EV_F06.15940.15940.2 0.567 12-Jul R.LLLLDC[160.03]R.S sp|Q99956|DUS9_HUMAN 1 901.5055 3.09 48926 15940 2 901.503302 451.76 Dual specificity protein phosphatase 9 OS=Homo sapiens OX=9606 GN=DUSP9 PE=1 SV=1 5.83 3264.1 - 812969 - - - -2.4637 - 1.632 0.107 - 181.3 1 2 0 -0.0022 7 0 0 0 3.36E+07 1.09E+07 - - - 1.3826 0.8913 230117_WJC_METTL3_WT_vs_EV_F06.15941.15941.2 3.04 14-Sep R.TAYLLYYR[166.11].R sp|Q14694|UBP10_HUMAN 1 1071.5629 1.06 48927 15941 2 1071.560229 536.7887 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.16 3264.3 - 571560 - - - -2.4478 - 1.15 0.085 - 176.2 1 2 0 -0.0026 8 0 0 0 4.33E+07 4.07E+07 - - - 0.0895 0.9861 230117_WJC_METTL3_WT_vs_EV_F06.15945.15945.2 0.437 12-Jul K.ILIEDWK.K "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A7I2V2T6|A0A7I2V2T6_HUMAN,tr|K7EPW7|K7EPW7_HUMAN" 4 915.5066 1.39 48930 15945 2 915.506659 458.7606 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 4.37 3264.7 - 1.24E+06 - - - 0.0983 - 1.376 0.057 - 130.3 1 2 0 0.0001 7 0 0 0 4.27E+07 3.06E+07 - - - 0.4733 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.15947.15947.2 5.76E-05 16-Oct R.MNVLADALK[136.11].S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 981.5409 1.32 48931 15947 2 981.537855 491.7777 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3264.9 - 809819 - - - -3.0544 - 1.805 0.466 - 249 1 2 0 -0.003 9 0 0 0 4.37E+08 3.31E+08 - - - 4.1905 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.15948.15948.2 0.00259 16-Sep R.MNVLADALK.S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 973.5267 1.32 48932 15948 2 973.527016 487.7706 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3265.1 - 590320 - - - 0.3729 - 1.857 0.327 - 202.9 1 2 0 0.0004 9 0 0 0 4.37E+08 3.31E+08 - - - 3.2468 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.15970.15970.2 0.073 18-Sep K.ILPEEITNLR.N sp|Q9H9A6|LRC40_HUMAN 1 1196.6765 0.83 48947 15970 2 1196.677196 599.3455 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3267.8 - 736116 - - - 0.5916 - 1.642 0.337 - 303.3 1 2 0 0.0007 10 0 0 0 3.54E+07 4.28E+07 - - - 2.9141 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.15979.15979.2 0.00039 16-Aug K.VLPVGVLYK[136.11].V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 994.6307 0.54 48952 15979 2 994.629766 498.3226 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3268.9 - 1.10E+07 - - - -0.8928 - 1.601 0.337 - 232.5 1 2 0 -0.0009 9 0 0 0 1.24E+08 2.29E+08 - - - 2.8914 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.15989.15989.2 0.000575 18-Sep K.ILPEEITNLR[166.11].N sp|Q9H9A6|LRC40_HUMAN 1 1206.6848 0.83 48955 15989 2 1206.689898 604.3497 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3270.5 - 539671 - - - 4.2596 - 1.748 0.426 - 287.1 1 2 0 0.0051 10 0 0 0 3.54E+07 4.28E+07 - - - 3.7447 0.9952 230117_WJC_METTL3_WT_vs_EV_F06.15990.15990.2 0.158 16-Jun K.VIIDTLITK[136.11].L sp|O15164|TIF1A_HUMAN 1 1022.6467 0.46 48956 15990 2 1022.648823 512.3306 Transcription intermediary factor 1-alpha OS=Homo sapiens OX=9606 GN=TRIM24 PE=1 SV=3 5.81 3270.7 - 226745 - - - 2.0779 - 1.171 0.217 - 60.4 1 2 0 0.0021 9 0 0 0 1.18E+07 2.54E+07 - - - 1.0998 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.15991.15991.3 6.04E-05 Nov-36 R.ILIAK[136.11]PIMFR[166.11].G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1218.7641 1.52 48957 15991 3 1218.764649 407.262 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3270.8 - 4.21E+06 - - - 0.4168 - 2.172 0.487 - 118.5 1 2 0 0.0005 10 0 0 0 1.19E+08 7.83E+07 - - - 6.2347 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.15993.15993.2 0.0158 20-Dec R.ILMVGLDAAGK[136.11].T "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|F5H1V1|F5H1V1_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|F5H6T5|F5H6T5_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|F8WDB3|F8WDB3_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 11 1094.6249 1.68 48959 15993 2 1094.624482 548.3197 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3270.9 - 2.95E+06 - - - -0.3974 - 2.353 0.422 - 398.6 1 2 0 -0.0004 11 0 0 0 2.44E+08 1.45E+08 - - - 4.4726 0.9953 230117_WJC_METTL3_WT_vs_EV_F06.15994.15994.2 0.608 16-Dec R.TEIIILATR[166.11].T "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 10 1038.6313 1.86 48960 15994 2 1038.62735 520.3229 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.66 3271.1 - 1.97E+06 - - - -3.7703 - 2.379 0.345 - 696.7 1 2 0 -0.0039 9 0 0 0 8.43E+08 4.52E+08 - - - 4.0953 0.9962 230117_WJC_METTL3_WT_vs_EV_F06.15996.15996.2 4.19E-05 20-Oct R.LVDAVLGAEIR[166.11].N "sp|Q9UBN7|HDAC6_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8Y758|A0A2R8Y758_HUMAN,tr|A0A2R8Y559|A0A2R8Y559_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 5 1164.6742 0.88 48962 15996 2 1164.669927 583.3444 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.37 3271.3 - 116365 - - - -3.6628 - 2.192 0.451 - 195 1 2 0 -0.0043 11 0 0 0 2.63E+07 2.98E+07 - - - 4.4939 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.16001.16001.2 0.0861 18-Oct R.ILIAKPIMFR.G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1200.7417 1.3 48965 16001 2 1200.742625 601.3781 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3271.9 - 549952 - - - 0.7945 - 2.067 0.327 - 314.3 1 2 0 0.001 10 0 0 0 7.76E+06 5.95E+06 - - - 3.4827 0.9998 230117_WJC_METTL3_WT_vs_EV_F06.16002.16002.3 0.00243 13/36 R.ILIAKPIMFR.G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1200.7417 1.45 48966 16002 3 1200.742219 401.2545 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3271.9 - 7.87E+06 - - - 0.4564 - 2.084 0.371 - 188.1 1 2 0 0.0005 10 0 0 0 1.13E+08 7.79E+07 - - - 4.8206 0.999 230117_WJC_METTL3_WT_vs_EV_F06.16003.16003.2 0.149 14-Sep R.TLINELVK[136.11].G "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 7 936.5735 29.82 48967 16003 2 936.574902 469.294 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.66 3272 - 4.02E+06 - - - 1.4617 - 1.387 0.32 - 226.9 1 2 0 0.0014 8 0 0 0 1.88E+09 6.30E+07 - - - 2.3907 0.9946 230117_WJC_METTL3_WT_vs_EV_F06.16004.16004.2 0.398 18-Jul R.ILIAK[136.11]PIMFR[166.11].G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1218.7641 1.3 48968 16004 2 1218.764033 610.3893 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3272.1 - 456380 - - - -0.0886 - 1.484 0.15 - 140.9 1 2 0 -0.0001 10 0 0 0 7.76E+06 5.95E+06 - - - 1.2507 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.16009.16009.2 3.10E-06 16-Sep K.VIVPNMEFR.A sp|P55060|XPO2_HUMAN 1 1103.5798 1.29 48971 16009 2 1103.58284 552.7972 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.97 3272.6 - 773950 - - - 2.7991 - 1.771 0.499 - 254.3 1 2 0 0.0031 9 0 0 0 1.10E+08 8.50E+07 - - - 4.3792 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.16010.16010.2 0.0249 20-Jul K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.12 48972 16010 2 1235.764812 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3272.8 - 616839 - - - 3.7661 - 1.679 0.361 - 158.7 1 2 0 0.0047 11 0 0 0 2.96E+08 2.63E+08 - - - 3.1077 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.16011.16011.2 0.172 12-Jun R.EEYLLLR.L "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 934.5124 1.26 48973 16011 2 934.513307 468.2635 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.53 3272.9 - 2.24E+06 - - - 0.9888 - 1.276 0.299 - 173.9 1 2 0 0.0009 7 0 0 0 5.23E+07 4.14E+07 - - - 2.0214 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.16012.16012.2 0.0532 14-Aug K.AVWLPAVK[136.11].A "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 890.5469 1.5 48974 16012 2 890.548657 446.2807 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.8 3273 - 895245 - - - 1.946 - 1.446 0.264 - 218.6 1 2 0 0.0017 8 0 0 0 3.33E+07 2.23E+07 - - - 2.1026 1 230117_WJC_METTL3_WT_vs_EV_F06.16017.16017.2 1.54E-06 13/20 R.LVDAVLGAEIR.N "sp|Q9UBN7|HDAC6_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8Y758|A0A2R8Y758_HUMAN,tr|A0A2R8Y559|A0A2R8Y559_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 5 1154.6659 0.88 48977 16017 2 1154.668521 578.3402 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.37 3273.6 - 582283 - - - 2.25 - 2.543 0.549 - 604 1 2 0 0.0026 11 0 0 0 2.63E+07 2.98E+07 - - - 5.62 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.16023.16023.2 0.0625 13/20 K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.12 48981 16023 2 1245.769471 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3274.4 - 1.02E+06 - - - 0.8372 - 1.915 0.378 - 409.4 1 2 0 0.001 11 0 0 0 2.96E+08 2.63E+08 - - - 3.5902 0.9944 230117_WJC_METTL3_WT_vs_EV_F06.16024.16024.2 0.125 14-Jun K.LLFVPC[160.03]SR[166.11].V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 1000.5403 0.85 48982 16024 2 1000.540197 501.2774 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.25 3274.5 - 1.37E+06 - - - -0.1449 - 1.282 0.197 - 115 1 2 0 -0.0001 8 0 0 0 3.70E+07 4.36E+07 - - - 1.2452 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.16025.16025.2 0.0548 14-Sep K.AVWLPAVK.A "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 882.5327 1.46 48983 16025 2 882.534375 442.2736 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.8 3274.7 - 1.09E+06 - - - 1.8708 - 1.433 0.207 - 274.5 1 2 0 0.0017 8 0 0 0 3.33E+07 2.28E+07 - - - 1.6544 0.8697 230117_WJC_METTL3_WT_vs_EV_F06.16026.16026.2 0.42 12-Jul R.QLSVLFR.K sp|Q96HR3|MED30_HUMAN 1 861.5072 3.23 48984 16026 2 861.513291 431.7609 Mediator of RNA polymerase II transcription subunit 30 OS=Homo sapiens OX=9606 GN=MED30 PE=1 SV=1 9.75 3274.8 - 497793 - - - 7.0261 - 1.413 0.102 - 166.9 1 2 0 0.0061 7 0 0 0 2.10E+07 6.49E+06 - - - 0.8879 1 230117_WJC_METTL3_WT_vs_EV_F06.16027.16027.2 2.34E-06 18-Nov K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 8.42 48985 16027 2 1149.584025 575.7982 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3274.9 - 493482 - - - 1.8842 - 2.205 0.505 - 490.1 1 2 0 0.0022 10 0 0 0 7.93E+08 9.41E+07 - - - 4.9774 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.16028.16028.2 0.135 24-Sep K.LGPGAGAGFGVLR.R "sp|Q9BUL5|PHF23_HUMAN,tr|I3L1N0|I3L1N0_HUMAN,tr|I3L410|I3L410_HUMAN,tr|I3L4Q4|I3L4Q4_HUMAN" 4 1170.6509 4.28 48986 16028 2 1170.653274 586.3327 PHD finger protein 23 OS=Homo sapiens OX=9606 GN=PHF23 PE=1 SV=1 9.75 3275.1 - 253732 - - - 1.9921 - 1.83 0.296 - 165.5 1 2 0 0.0023 13 0 0 0 1.61E+07 3.76E+06 - - - 2.7775 0.9933 230117_WJC_METTL3_WT_vs_EV_F06.16033.16033.2 0.177 12-Jul R.MIEFVVR.E "sp|O15042|SR140_HUMAN,tr|E7ET15|E7ET15_HUMAN" 2 892.4841 1.83 48989 16033 2 892.483482 447.2493 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 5.75 3275.7 - 337599 - - - -0.6465 - 1.063 0.286 - 166.7 1 2 0 -0.0006 7 0 0 0 2.44E+07 1.34E+07 - - - 1.3468 1 230117_WJC_METTL3_WT_vs_EV_F06.16034.16034.2 0.00506 18-Nov K.FAEAFEAIPR[166.11].A sp|P50990|TCPQ_HUMAN 1 1159.5901 8.44 48990 16034 2 1159.592625 580.8023 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3275.9 - 151093 - - - 2.1525 - 2.311 0.498 - 419.8 1 2 0 0.0025 10 0 0 0 7.92E+08 9.38E+07 - - - 5.0567 0.8765 230117_WJC_METTL3_WT_vs_EV_F06.16038.16038.2 10.1 12-Jul L.LLAILER[166.11].C "sp|Q6ZMB5|T184A_HUMAN,sp|Q6ZQQ2|S31D1_HUMAN" 2 836.5359 1 48992 16038 2 836.536595 419.2752 Transmembrane protein 184A OS=Homo sapiens OX=9606 GN=TMEM184A PE=1 SV=1 6 3276.3 - 1.17E+06 - - - 0.82 - 1.774 0.139 - 155.9 1 1 0 0.0007 7 0 0 0 1.51E+08 1.51E+08 - - - 1.8838 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16041.16041.2 0.000858 18-Oct R.TVPLLLAESK[136.11].F sp|Q709C8|VP13C_HUMAN 1 1077.6525 1.01 48995 16041 2 1077.653079 539.8335 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 5.66 3276.7 - 391774 - - - 0.5271 - 1.723 0.384 - 294 1 2 0 0.0006 10 0 0 0 8.17E+06 8.11E+06 - - - 3.3957 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.16042.16042.2 1.6 18-Nov R.LPAAFAPLPR.V "sp|O14561|ACPM_HUMAN,tr|H3BNE8|H3BNE8_HUMAN,tr|H3BNK3|H3BNK3_HUMAN" 3 1051.6179 1.66 48996 16042 2 1051.618168 526.8162 "Acyl carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAB1 PE=1 SV=3" 9.75 3276.9 - 346535 - - - 0.3014 - 1.631 0.212 - 182.1 1 2 0 0.0003 10 0 0 0 7.01E+06 4.21E+06 - - - 1.9722 0.8719 230117_WJC_METTL3_WT_vs_EV_F06.16046.16046.2 0.554 12-Aug S.LIQLLGR.N "sp|Q9P035|HACD3_HUMAN,sp|P82930|RT34_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN,tr|C9JJ19|C9JJ19_HUMAN,tr|H3BMZ1|H3BMZ1_HUMAN,tr|H3BRL8|H3BRL8_HUMAN" 7 811.528 1.14 48998 16046 2 811.529642 406.7713 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 9.75 3277.4 - 2.50E+06 - - - 2.0566 - 1.724 0.154 - 225 1 1 0 0.0017 7 0 0 0 2.87E+08 2.51E+08 - - - 1.9037 0.997 230117_WJC_METTL3_WT_vs_EV_F06.16049.16049.2 0.736 14-Jul K.LFIGNLPR[166.11].E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 938.5577 2.18 49001 16049 2 938.558351 470.2861 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3277.7 - 925453 - - - 0.6862 - 1.304 0.217 - 138.9 1 2 0 0.0006 8 0 0 0 2.61E+09 1.20E+09 - - - 1.4441 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.16058.16058.2 0.00991 16-May K.VIVPNMEFR[166.11].A sp|P55060|XPO2_HUMAN 1 1113.588 1.29 49007 16058 2 1113.59047 557.8013 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.97 3278.7 - 2.91E+06 - - - 2.1992 - 1.442 0.423 - 89.9 1 2 0 0.0024 9 0 0 0 1.10E+08 8.50E+07 - - - 3.2235 0.9876 230117_WJC_METTL3_WT_vs_EV_F06.16061.16061.2 0.166 12-May K.WPVAWGK.L "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 842.4439 1.18 49009 16061 2 842.444947 422.2292 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.75 3279 - 293078 - - - 1.2321 - 1.07 0.163 - 50 2 2 0 0.001 7 0 0 0 7.83E+06 6.65E+06 - - - 0.3245 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.16067.16067.2 0.377 12-Jul K.VFGIQLK.E "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN" 3 803.4905 5.68 49012 16067 2 803.492224 402.7525 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 8.72 3279.8 - 2.55E+06 - - - 2.1145 - 1.293 0.183 - 161.7 1 2 0 0.0017 7 0 0 0 4.32E+07 7.60E+06 - - - 1.2063 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.16069.16069.2 0.00619 14-Jul K.ELPTVVFR[166.11].A sp|Q9BVP2|GNL3_HUMAN 1 969.5523 0.94 49014 16069 2 969.554235 485.7834 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 6.1 3279.9 - 5.12E+06 - - - 2.0092 - 1.455 0.371 - 242 1 2 0 0.0019 8 0 0 0 9.70E+07 1.03E+08 - - - 2.9116 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.16074.16074.2 0.00088 14-Sep K.FC[160.03]ELLIGR.G "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1006.527 999 49017 16074 2 1006.530858 504.2708 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.99 3280.5 - 943528 - - - 3.8459 - 1.687 0.425 - 309.4 1 2 0 0.0039 8 0 0 0 1.50E+08 0.00E+00 - - - 3.756 0.898 230117_WJC_METTL3_WT_vs_EV_F06.16079.16079.2 0.204 12-Sep A.IIAELLR.L "sp|Q12768|WASC5_HUMAN,sp|P16444|DPEP1_HUMAN,sp|Q9Y4D8|HECD4_HUMAN,sp|Q7L2E3|DHX30_HUMAN,sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HJX8|A0A804HJX8_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A494C150|A0A494C150_HUMAN,tr|A0A804HJG8|A0A804HJG8_HUMAN,tr|F8VWT9|F8VWT9_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|H7BXY3|H7BXY3_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|J3KPF0|J3KPF0_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 24 826.5276 1 49021 16079 2 826.529218 414.2711 WASH complex subunit 5 OS=Homo sapiens OX=9606 GN=WASHC5 PE=1 SV=1 6 3281.1 - 5.86E+06 - - - 1.9104 - 1.676 0.193 - 271 1 1 0 0.0016 7 0 0 0 1.51E+08 1.51E+08 - - - 2.1023 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.16081.16081.2 0.035 14-Jul K.ELPTVVFR.A sp|Q9BVP2|GNL3_HUMAN 1 959.544 0.94 49022 16081 2 959.546813 480.7793 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 6.1 3281.3 - 6.52E+06 - - - 2.9139 - 1.32 0.341 - 218.6 1 2 0 0.0028 8 0 0 0 9.70E+07 1.03E+08 - - - 2.3961 0.999 230117_WJC_METTL3_WT_vs_EV_F06.16083.16083.2 0.00918 16-Aug K.VYEAVELLK.S sp|Q8TEQ6|GEMI5_HUMAN 1 1062.5961 0.62 49023 16083 2 1062.597409 532.3053 Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3 4.53 3281.6 - 1.41E+06 - - - 1.2206 - 1.303 0.351 - 172.9 1 2 0 0.0013 9 0 0 0 1.26E+07 2.02E+07 - - - 2.3988 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.16084.16084.3 0.144 Nov-36 K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 10.01 49024 16084 3 1149.582477 384.2012 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3281.7 - 893857 - - - 0.5376 - 1.631 0.356 - 231.8 1 2 0 0.0006 10 0 0 0 9.67E+06 9.67E+05 - - - 3.9375 0.9717 230117_WJC_METTL3_WT_vs_EV_F06.16088.16088.2 0.0754 24-Jun K.VLATAFDTTLGGR.K "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1320.7038 -1 49028 16088 2 1320.709821 661.3592 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.81 3282.2 - 81627.7 - - - 4.5854 - 1.512 0.109 - 90.4 1 2 0 0.0061 13 0 0 0 0.00E+00 0.00E+00 - - - 0.9053 0.999 230117_WJC_METTL3_WT_vs_EV_F06.16092.16092.2 0.000329 16-Aug K.IYPVGYFTK.E "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 1086.575 5.58 49030 16092 2 1086.575369 544.2948 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.5 3282.7 - 1.23E+06 - - - 0.3552 - 1.54 0.313 - 232 1 2 0 0.0004 9 0 0 0 6.76E+07 1.21E+07 - - - 2.6019 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.16098.16098.2 0.00923 20-Nov K.LLLIGDSGVGK.T "sp|P61006|RAB8A_HUMAN,sp|P51153|RAB13_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P59190|RAB15_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YL94|H0YL94_HUMAN,tr|A0A2R8YDI9|A0A2R8YDI9_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|G3V196|G3V196_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H0YLJ8|H0YLJ8_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN,tr|F5H157|F5H157_HUMAN" 19 1070.6336 1.48 49034 16098 2 1070.638469 536.3241 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.84 3283.5 - 2.32E+06 - - - 4.5851 - 1.877 0.384 - 324.8 1 2 0 0.0049 11 0 0 0 3.31E+08 2.24E+08 - - - 3.5791 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.16099.16099.2 0.0474 12-Jul K.MIFVGIK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 806.4724 2.24 49035 16099 2 806.473898 404.2435 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 8.5 3283.5 - 1.83E+06 - - - 1.8178 - 1.338 0.241 - 229.3 1 2 0 0.0015 7 0 0 0 2.67E+07 1.19E+07 - - - 1.7432 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.16100.16100.2 0.815 12-Jul K.IIAALFK.A "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 774.5004 2.08 49036 16100 2 774.50123 388.2575 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3283.6 - 578920 - - - 1.122 - 1.404 0.175 - 95.4 1 2 0 0.0009 7 0 0 0 2.71E+07 1.31E+07 - - - 1.4084 0.9783 230117_WJC_METTL3_WT_vs_EV_F06.16101.16101.2 3.19 14-Aug R.LLAMAVIR[166.11].K sp|Q96EK4|THA11_HUMAN 1 895.5553 0.14 49037 16101 2 895.55666 448.7849 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 9.75 3283.8 - 409368 - - - 1.5588 - 1.267 0.027 - 152.7 1 2 0 0.0014 8 0 0 0 9.79E+06 7.14E+07 - - - -0.0463 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.16105.16105.2 0.0605 18-Jun K.ILVEEMAPLK.G "sp|Q16670|ZSC26_HUMAN,tr|A0A087WXM4|A0A087WXM4_HUMAN,tr|A0A024RCN4|A0A024RCN4_HUMAN,tr|A0A087X2F1|A0A087X2F1_HUMAN" 4 1141.6417 4.33 49041 16105 2 1141.644767 571.8281 Zinc finger and SCAN domain-containing protein 26 OS=Homo sapiens OX=9606 GN=ZSCAN26 PE=1 SV=2 4.53 3284.2 - 0 - - - 2.7022 - 1.489 0.28 - 66.7 2 2 0 0.0031 10 0 0 0 3.07E+06 7.09E+05 - - - 2.0849 0.998 230117_WJC_METTL3_WT_vs_EV_F06.16107.16107.2 0.576 14-Aug K.LFIGNLPR.E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 928.5494 2.18 49042 16107 2 928.551165 465.282 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3284.5 - 3.18E+07 - - - 1.861 - 1.467 0.214 - 282.5 1 2 0 0.0017 8 0 0 0 2.61E+09 1.20E+09 - - - 1.7768 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.16110.16110.2 0.0689 12-Jul K.FGDFVLK.S "sp|P11172|UMPS_HUMAN,tr|F2Z303|F2Z303_HUMAN,tr|F2Z3P2|F2Z3P2_HUMAN,tr|F8WDG4|F8WDG4_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 5 824.4432 1.91 49044 16110 2 824.444068 413.2289 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 5.84 3284.8 - 3.64E+06 - - - 1.0043 - 1.306 0.231 - 120.4 1 2 0 0.0008 7 0 0 0 5.12E+07 2.68E+07 - - - 1.5928 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.16113.16113.2 0.513 12-Sep K.IIAALFK[136.11].A "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 782.5146 2.11 49047 16113 2 782.515498 392.2646 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3285.1 - 1.08E+06 - - - 1.1974 - 1.791 0.139 - 200.3 1 2 0 0.0009 7 0 0 0 2.76E+07 1.31E+07 - - - 1.9139 1 230117_WJC_METTL3_WT_vs_EV_F06.16116.16116.2 1.63E-06 20-Nov K.NSLESYAFNMK.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1302.5914 80.04 49050 16116 2 1302.590285 652.303 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6 3285.5 - 141130 - - - -0.8852 - 2.37 0.556 - 466.3 1 2 0 -0.0012 11 0 0 0 1.19E+07 1.49E+05 - - - 5.4816 0.994 230117_WJC_METTL3_WT_vs_EV_F06.16119.16119.2 0.126 12-Jun K.LFQLYPR[166.11].N sp|Q8IXM3|RM41_HUMAN 1 945.5312 1.12 49052 16119 2 945.531264 473.7729 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 8.75 3285.9 - 5.25E+06 - - - 0.1121 - 1.424 0.125 - 141.1 1 2 0 0.0001 7 0 0 0 1.66E+08 1.47E+08 - - - 1.0842 0.9944 230117_WJC_METTL3_WT_vs_EV_F06.16121.16121.2 0.191 16-May R.IVATLPYIK[136.11].Q "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1024.6412 1.32 49053 16121 2 1024.641938 513.3279 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 8.59 3286.1 - 365777 - - - 0.7027 - 0.921 0.292 - 50.1 1 2 0 0.0007 9 0 0 0 8.59E+07 6.48E+07 - - - 0.9594 0.9965 230117_WJC_METTL3_WT_vs_EV_F06.16122.16122.2 0.718 14-Jul R.LLAMAVIR.K sp|Q96EK4|THA11_HUMAN 1 885.547 0.14 49054 16122 2 885.547924 443.7808 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 9.75 3286.2 - 378942 - - - 1.0502 - 1.317 0.189 - 148.8 1 2 0 0.0009 8 0 0 0 9.79E+06 6.78E+07 - - - 1.2671 0.8661 230117_WJC_METTL3_WT_vs_EV_F06.16125.16125.2 0.0376 14-Jul R.PLELSDFR[166.11].M "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 985.5108 1.7 49057 16125 2 985.512154 493.7627 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.37 3286.4 - 375367 - - - 1.3577 - 1.465 0.21 - 186.4 1 1 0 0.0013 8 0 0 0 4.11E+07 2.42E+07 - - - 1.7433 0.9883 230117_WJC_METTL3_WT_vs_EV_F06.16132.16132.2 0.603 14-Jul R.LISLPLSR[166.11].L "sp|Q9NRG0|CHRC1_HUMAN,tr|E5RGS9|E5RGS9_HUMAN" 2 907.573 1.82 49062 16132 2 907.574546 454.7938 Chromatin accessibility complex protein 1 OS=Homo sapiens OX=9606 GN=CHRAC1 PE=1 SV=1 9.75 3287.1 - 1.93E+06 - - - 1.6781 - 1.343 0.061 - 120.5 1 2 0 0.0015 8 0 0 0 7.13E+07 3.91E+07 - - - 0.3805 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.16133.16133.2 0.18 16-Aug K.LTLLQVASR.Q sp|O95239|KIF4A_HUMAN 1 999.6077 2.14 49063 16133 2 999.608826 500.8111 Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3 9.75 3287.2 - 1.22E+06 - - - 1.1464 - 1.793 0.264 - 179.7 1 2 0 0.0011 9 0 0 0 1.99E+07 9.29E+06 - - - 2.6798 0.9946 230117_WJC_METTL3_WT_vs_EV_F06.16136.16136.2 0.432 14-Sep K.GGLGLILK.R "sp|O75832|PSD10_HUMAN,tr|B1AJY5|B1AJY5_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 3 769.5062 1.61 49066 16136 2 769.507127 385.7604 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 8.75 3287.6 - 1.12E+06 - - - 1.2372 - 1.454 0.101 - 203.8 1 2 0 0.001 8 0 0 0 7.67E+07 4.75E+07 - - - 0.9156 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.16137.16137.2 0.00875 14-Jul R.GFVLYPVK.Y sp|P62487|RPB7_HUMAN 1 921.5324 0.01 49067 16137 2 921.535522 461.7735 DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1 8.59 3287.8 - 520183 - - - 3.3987 - 1.334 0.381 - 140 1 2 0 0.0031 8 0 0 0 1.65E+07 1.30E+09 - - - 2.7232 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.16139.16139.2 0.00272 12-Jun R.EYFYGFR.G "sp|Q92989|CLP1_HUMAN,tr|E9PL17|E9PL17_HUMAN" 2 980.4392 3.88 49069 16139 2 980.440903 491.2269 Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1 6.1 3288 - 381179 - - - 1.7186 - 1.229 0.319 - 126.5 1 2 0 0.0017 7 0 0 0 4.03E+06 1.04E+06 - - - 2.05 0.9951 230117_WJC_METTL3_WT_vs_EV_F06.16143.16143.2 8.81 14-Aug K.GGLGLILK[136.11].R "sp|O75832|PSD10_HUMAN,tr|B1AJY5|B1AJY5_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 3 777.5204 1.61 49071 16143 2 777.522102 389.7675 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 8.75 3288.6 - 1.65E+06 - - - 2.2212 - 1.646 0.079 - 140.3 1 2 0 0.0017 8 0 0 0 7.67E+07 4.75E+07 - - - 1.1269 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16146.16146.2 0.0371 18-Sep K.AMTILLEEAK.A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1117.6053 2.11 49074 16146 2 1117.60593 559.8099 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3288.9 - 340702 - - - 0.5664 - 2.13 0.321 - 230.3 1 2 0 0.0006 10 0 0 0 3.98E+07 1.88E+07 - - - 3.5223 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.16152.16152.2 0.33 14-Jul R.LEEIPLIK.S sp|Q14152|EIF3A_HUMAN 1 953.5797 0.96 49078 16152 2 953.579832 477.7971 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 3289.6 - 1.18E+06 - - - 0.1028 - 1.565 0.179 - 125.3 1 2 0 0.0001 8 0 0 0 7.43E+07 7.75E+07 - - - 1.7139 0.9955 230117_WJC_METTL3_WT_vs_EV_F06.16154.16154.2 0.0861 12-Jun R.LIFDNLK[136.11].K "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P54707|AT12A_HUMAN,sp|P20648|ATP4A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 11 869.5102 1.28 49080 16154 2 869.512062 435.7624 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.84 3289.7 - 1.01E+06 - - - 2.1368 - 1.063 0.263 - 88.1 1 2 0 0.0019 7 0 0 0 6.22E+07 4.86E+07 - - - 1.1765 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.16155.16155.2 1.13 12-Aug R.LSAIFLR.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 818.5014 1.65 49081 16155 2 818.50228 410.258 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3289.8 - 622194 - - - 1.0458 - 1.673 0.103 - 213.2 1 2 0 0.0009 7 0 0 0 4.82E+07 2.92E+07 - - - 1.4321 1 230117_WJC_METTL3_WT_vs_EV_F06.16160.16160.2 5.32E-06 18-Dec K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 409.92 49084 16160 2 1146.630898 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3290.4 - 1.22E+06 - - - 2.1132 - 2.236 0.519 - 402.9 1 2 0 0.0024 10 0 0 0 4.19E+09 1.02E+07 - - - 5.1197 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.16161.16161.2 3.34 12-Aug R.LSAIFLR[166.11].L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 828.5097 1.68 49085 16161 2 828.510753 415.2621 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3290.5 - 540648 - - - 1.2782 - 1.854 0.167 - 168.3 1 2 0 0.0011 7 0 0 0 4.86E+07 2.88E+07 - - - 2.2302 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.16164.16164.2 0.0244 18-Sep K.AMTILLEEAK[136.11].A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1125.6195 2.11 49088 16164 2 1125.61937 563.817 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3290.9 - 162510 - - - -0.1128 - 1.929 0.356 - 265.3 1 2 0 -0.0001 10 0 0 0 3.98E+07 1.88E+07 - - - 3.5043 0.998 230117_WJC_METTL3_WT_vs_EV_F06.16169.16169.2 0.0127 20-Oct K.C[160.03]ILVASPGFVR.E sp|Q9BRX2|PELO_HUMAN 1 1217.6591 4.09 49091 16169 2 1217.661968 609.8368 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 8.25 3291.6 - 340168 - - - 2.3849 - 1.711 0.199 - 275.9 1 2 0 0.0029 11 0 0 0 1.80E+07 4.40E+06 - - - 1.9628 0.9221 230117_WJC_METTL3_WT_vs_EV_F06.16170.16170.2 0.00995 16-Aug R.WLNYGGVIK.N "sp|P49642|PRI1_HUMAN,tr|F8VSB2|F8VSB2_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN" 3 1048.5706 0.3 49092 16170 2 1048.579132 525.2926 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 8.59 3291.7 - 341897 - - - 8.1692 - 1.358 0.252 - 172 1 2 0 0.0086 9 0 0 0 2.33E+06 7.85E+06 - - - 1.7849 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.16171.16171.2 0.0243 16-Oct K.VVDVLDSIK[136.11].T sp|P00918|CAH2_HUMAN 1 994.579 0.83 49093 16171 2 994.581635 498.2968 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.21 3291.8 - 340434 - - - 2.6373 - 2.091 0.212 - 274.1 1 2 0 0.0026 9 0 0 0 2.48E+07 2.98E+07 - - - 2.74 1 230117_WJC_METTL3_WT_vs_EV_F06.16175.16175.2 0.0165 16-Sep R.FDDPLLGPR[166.11].R "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 8 1038.5374 0.96 49095 16175 2 1038.54047 520.276 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.21 3292.3 - 353062 - - - 2.9898 - 2.024 0.476 - 249.7 1 2 0 0.0031 9 0 0 0 6.89E+07 7.19E+07 - - - 4.5956 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.16178.16178.2 0.0344 14-Aug R.LEEIPLIK[136.11].S sp|Q14152|EIF3A_HUMAN 1 961.5939 0.95 49097 16178 2 961.593627 481.8042 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 3292.6 - 2.03E+06 - - - -0.3193 - 1.869 0.137 - 173 1 2 0 -0.0003 8 0 0 0 7.38E+07 7.75E+07 - - - 1.939 0.9645 230117_WJC_METTL3_WT_vs_EV_F06.16182.16182.2 2.07 12-Jul R.NLVLLVR.E sp|Q9H2W6|RM46_HUMAN 1 825.5436 1.07 49099 16182 2 825.546312 413.7791 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 9.75 3293.1 - 1.37E+06 - - - 3.2572 - 1.401 0.001 - 220.1 1 2 0 0.0027 7 0 0 0 5.05E+07 4.72E+07 - - - 0.1159 0.9921 230117_WJC_METTL3_WT_vs_EV_F06.16183.16183.2 0.67 16-Aug K.VVDVLDSIK.T sp|P00918|CAH2_HUMAN 1 986.5648 0.83 49100 16183 2 986.567494 494.2897 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.21 3293.2 - 924208 - - - 2.7185 - 1.218 0.183 - 147.3 1 2 0 0.0027 9 0 0 0 2.48E+07 2.98E+07 - - - 0.9623 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.16185.16185.2 0.0504 20-Aug K.C[160.03]ILVASPGFVR[166.11].E sp|Q9BRX2|PELO_HUMAN 1 1227.6673 4.07 49102 16185 2 1227.670076 614.8409 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 8.25 3293.4 - 326570 - - - 2.2335 - 1.587 0.205 - 181.9 1 2 0 0.0027 11 0 0 0 1.79E+07 4.40E+06 - - - 1.8037 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16188.16188.2 0.0131 18-Oct K.LLADELISPK[136.11].D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1105.6474 1.1 49103 16188 2 1105.649796 553.831 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3293.8 - 1.15E+06 - - - 2.1435 - 1.882 0.372 - 203.3 1 2 0 0.0024 10 0 0 0 6.60E+07 6.02E+07 - - - 3.5529 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.16189.16189.2 0.0117 14-Aug R.LLNTFLER.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 8 1004.5655 1.38 49104 16189 2 1004.564492 503.29 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3293.9 - 963689 - - - -0.9845 - 1.69 0.295 - 164.7 1 2 0 -0.001 8 0 0 0 1.50E+08 1.09E+08 - - - 2.8021 0.9877 230117_WJC_METTL3_WT_vs_EV_F06.16196.16196.2 0.0835 12-Jun K.MFEFYER.V "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 13 1020.4375 1.95 49109 16196 2 1020.441149 511.226 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3294.7 - 1.43E+06 - - - 3.573 - 1.363 0.135 - 169.7 1 2 0 0.0036 7 0 0 0 2.50E+07 1.28E+07 - - - 1.0182 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.16197.16197.2 0.08 12-Jul R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 137.28 49110 16197 2 806.39419 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 3294.8 - 1.12E+06 - - - 2.3847 - 1.589 0.252 - 178.7 1 2 0 0.0019 7 0 0 0 4.95E+07 3.61E+05 - - - 2.369 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.16204.16204.2 0.451 12-Sep K.ILPDILK.K "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 810.5215 1.76 49115 16204 2 810.522625 406.268 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 3295.7 - 2.36E+06 - - - 1.3991 - 1.491 0.166 - 221 1 2 0 0.0011 7 0 0 0 9.58E+07 5.43E+07 - - - 1.5324 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.16205.16205.2 0.169 14-Jul M.VLLTMIAR.V sp|O75396|SC22B_HUMAN 1 915.5576 0.49 49116 16205 2 915.558957 458.7861 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 9.72 3295.8 - 1.92E+06 - - - 1.5269 - 1.42 0.212 - 156.4 1 2 0 0.0014 8 0 0 0 7.24E+07 1.47E+08 - - - 1.664 0.9864 230117_WJC_METTL3_WT_vs_EV_F06.16209.16209.2 0.0242 16-Jun R.LMGSILGVR[166.11].R "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 954.556 1.29 49118 16209 2 954.557236 478.2853 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 9.75 3296.3 - 4.13E+06 - - - 1.3032 - 1.442 0.064 - 46.4 5 2 0 0.0012 9 0 0 0 5.17E+07 4.00E+07 - - - 0.26 0.991 230117_WJC_METTL3_WT_vs_EV_F06.16210.16210.2 1.43 12-Jul K.ILPDILK[136.11].K "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 818.5357 2.46 49119 16210 2 818.536911 410.2751 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 3296.4 - 4.21E+06 - - - 1.4905 - 1.291 0.094 - 105.3 1 2 0 0.0012 7 0 0 0 9.23E+07 3.76E+07 - - - 0.5442 0.999 230117_WJC_METTL3_WT_vs_EV_F06.16211.16211.2 0.00805 18-Aug R.LTPLQLEIQR.V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1209.7081 1.17 49120 16211 2 1209.708055 605.8613 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 3296.5 - 4.39E+06 - - - -0.0554 - 1.597 0.335 - 245.3 1 2 0 -0.0001 10 0 0 0 4.20E+07 3.60E+07 - - - 2.822 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.16212.16212.2 0.0274 18-Aug R.LTPLQLEIQR[166.11].V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1219.7164 1.17 49121 16212 2 1219.717938 610.8655 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 3296.6 - 4.27E+06 - - - 1.2675 - 1.667 0.321 - 284.3 1 2 0 0.0015 10 0 0 0 4.20E+07 3.60E+07 - - - 2.8378 0.9746 230117_WJC_METTL3_WT_vs_EV_F06.16213.16213.2 5.59 12-Jun K.AFIVELR[166.11].Q sp|O43318|M3K7_HUMAN 1 856.5046 1.09 49122 16213 2 856.505473 429.2596 Mitogen-activated protein kinase kinase kinase 7 OS=Homo sapiens OX=9606 GN=MAP3K7 PE=1 SV=1 6.05 3296.6 - 1.06E+06 - - - 1.0088 - 1.075 0.08 - 124 1 2 0 0.0009 7 0 0 0 9.92E+06 9.14E+06 - - - -0.1392 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.16214.16214.2 0.065 20-Sep K.LLDSITVPVAR[166.11].A sp|O00203|AP3B1_HUMAN 1 1192.7055 1.36 49123 16214 2 1192.705296 597.36 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3296.8 - 632036 - - - -0.1652 - 1.69 0.377 - 179.9 1 2 0 -0.0002 11 0 0 0 2.64E+07 1.94E+07 - - - 3.245 0.9879 230117_WJC_METTL3_WT_vs_EV_F06.16219.16219.2 0.152 16-Jul R.IVLNGIDLK.A sp|O15294|OGT1_HUMAN 1 983.6015 2.02 49125 16219 2 983.604271 492.808 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 5.84 3297.4 - 1.05E+06 - - - 2.7847 - 1.309 0.116 - 76.8 1 2 0 0.0027 9 0 0 0 2.83E+07 1.41E+07 - - - 0.6759 0.9717 230117_WJC_METTL3_WT_vs_EV_F06.16221.16221.2 0.062 14-Jun K.FYSFALDK[136.11].T sp|Q96T58|MINT_HUMAN 1 997.5 0.89 49127 16221 2 997.505854 499.7573 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.83 3297.6 - 1.62E+06 - - - 5.8346 - 1.216 0.264 - 93 1 2 0 0.0058 8 0 0 0 2.96E+07 3.32E+07 - - - 1.5789 0.9212 230117_WJC_METTL3_WT_vs_EV_F06.16222.16222.2 0.0186 14-Jul K.FYSFALDK.T sp|Q96T58|MINT_HUMAN 1 989.4858 0.85 49128 16222 2 990.490096 495.7502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.83 3297.6 - 1.07E+06 - - - 1014.9332 - 1.354 0.386 - 106.3 1 2 0 1.0043 8 0 0 0 2.80E+07 3.30E+07 - - - 2.4907 0.9328 230117_WJC_METTL3_WT_vs_EV_F06.16229.16229.2 0.201 14-Sep F.AFLWAGGR[166.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A1W2PNG3|A0A1W2PNG3_HUMAN" 12 886.4689 1.22 49133 16229 2 886.469622 444.2417 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.79 3298.6 - 4.49E+07 - - - 0.8235 - 1.693 0.261 - 437.8 1 1 0 0.0007 8 0 0 0 1.50E+09 1.23E+09 - - - 2.5564 0.9803 230117_WJC_METTL3_WT_vs_EV_F06.16234.16234.2 0.0144 18-Jul K.IPVSGPFLVK.T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1055.6379 1.27 49138 16234 2 1055.638048 528.8262 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3299.2 - 161188 - - - 0.1231 - 1.394 0.053 - 75.6 2 2 0 0.0001 10 0 0 0 1.65E+08 1.31E+08 - - - 0.2252 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.16240.16240.2 0.000557 20-Aug K.LLDSITVPVAR.A sp|O00203|AP3B1_HUMAN 1 1182.6972 1.36 49142 16240 2 1182.69548 592.3559 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3299.9 - 2.02E+06 - - - -1.4737 - 1.724 0.434 - 146.2 1 2 0 -0.0017 11 0 0 0 2.64E+07 1.94E+07 - - - 3.7194 0.9823 230117_WJC_METTL3_WT_vs_EV_F06.16244.16244.2 0.0874 12-Jun K.LMVIFSK.V "sp|Q9BRK5|CAB45_HUMAN,tr|A0A5F9UJX7|A0A5F9UJX7_HUMAN,tr|A0A5F9UP49|A0A5F9UP49_HUMAN,tr|G3V1E2|G3V1E2_HUMAN,tr|H0Y3T6|H0Y3T6_HUMAN" 5 836.483 0.42 49144 16244 2 836.48393 419.2488 45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1 8.75 3300.4 - 454311 - - - 1.1154 - 1.399 0.016 - 107.9 2 2 0 0.0009 7 0 0 0 1.69E+07 4.04E+07 - - - 0.0883 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.16250.16250.2 0.00146 18-Oct K.LGLTEDQFIR.T "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1190.6295 3.51 49148 16250 2 1190.629437 596.322 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.37 3301.1 - 266235 - - - -0.0848 - 1.85 0.386 - 226.7 1 2 0 -0.0001 10 0 0 0 1.37E+07 3.91E+06 - - - 3.6091 0.8698 230117_WJC_METTL3_WT_vs_EV_F06.16251.16251.2 0.00486 22-Aug R.GLLQDDAHPTLV.T "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1277.6616 - 49149 16251 2 1277.660346 639.8381 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3301.2 - 166342 - - - -0.9549 - 1.684 0.318 - 93.2 1 1 0 -0.0012 12 0 0 0 - - - - - 2.7607 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.16253.16253.2 0.000279 18-Dec K.LLADELISPK.D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1097.6332 1.09 49150 16253 2 1097.634545 549.8239 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3301.5 - 2.26E+06 - - - 1.2017 - 2.185 0.312 - 389.6 1 2 0 0.0013 10 0 0 0 6.61E+07 6.05E+07 - - - 3.5267 0.9962 230117_WJC_METTL3_WT_vs_EV_F06.16258.16258.2 0.119 14-Aug K.STLFWGAR.Y "sp|Q96QA5|GSDMA_HUMAN,tr|J3KRG2|J3KRG2_HUMAN" 2 936.4818 1.26 49154 16258 2 936.483646 469.2482 Gasdermin-A OS=Homo sapiens OX=9606 GN=GSDMA PE=1 SV=4 9.47 3302 - 726129 - - - 2.0235 - 1.328 0.188 - 158.1 1 2 0 0.0019 8 0 0 0 1.17E+08 9.32E+07 - - - 1.2845 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.16262.16262.2 0.000255 15/22 K.LGALTAEEIALK.M sp|Q13601|KRR1_HUMAN 1 1227.7075 1.24 49156 16262 2 1227.70814 614.861 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3302.5 - 635571 - - - 0.5588 - 2.366 0.393 - 674.4 1 2 0 0.0007 12 0 0 0 1.46E+08 1.18E+08 - - - 4.2094 0.9962 230117_WJC_METTL3_WT_vs_EV_F06.16266.16266.2 0.0854 14-Jul K.VLTFDLTK.Y "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 935.5328 1.89 49158 16266 2 935.533337 468.7737 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.81 3303 - 2.70E+06 - - - 0.5911 - 1.158 0.244 - 135.8 1 2 0 0.0006 8 0 0 0 6.70E+07 3.55E+07 - - - 1.2854 0.8883 230117_WJC_METTL3_WT_vs_EV_F06.16267.16267.2 0.0572 20-Aug K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.06 49159 16267 2 1235.767918 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3303 - 3.05E+06 - - - 6.2795 - 1.564 0.058 - 204.7 1 2 0 0.0078 11 0 0 0 1.11E+08 1.05E+08 - - - 0.6769 0.9664 230117_WJC_METTL3_WT_vs_EV_F06.16268.16268.2 2.51 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 9.75 49160 16268 2 841.502462 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 3303.1 - 4.95E+06 - - - 0.3684 - 1.327 0.005 - 191.3 2 2 0 0.0003 8 0 0 0 3.49E+08 3.57E+07 - - - -0.2034 0.9727 230117_WJC_METTL3_WT_vs_EV_F06.16275.16275.2 0.00167 22-Nov R.VFASELNAGIIK[136.11].T "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1268.722 1.62 49165 16275 2 1268.732407 635.3683 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.97 3303.9 - 304279 - - - 8.2122 - 1.903 0.302 - 271.1 1 2 0 0.0104 12 0 0 0 1.48E+07 9.11E+06 - - - 2.9613 1 230117_WJC_METTL3_WT_vs_EV_F06.16276.16276.2 3.68E-05 15/22 K.LGALTAEEIALK[136.11].M sp|Q13601|KRR1_HUMAN 1 1235.7217 1.24 49166 16276 2 1235.721576 618.8681 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3304 - 2.15E+06 - - - -0.0631 - 2.609 0.494 - 591.6 1 2 0 -0.0001 12 0 0 0 1.46E+08 1.18E+08 - - - 5.2129 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.16277.16277.2 3.16 12-Jun K.DVLLPLK.S sp|Q9Y385|UB2J1_HUMAN 1 796.5058 1.83 49167 16277 2 796.50713 399.2602 Ubiquitin-conjugating enzyme E2 J1 OS=Homo sapiens OX=9606 GN=UBE2J1 PE=1 SV=2 5.84 3304.2 - 524542 - - - 1.6183 - 1.333 0.185 - 140.8 1 2 0 0.0013 7 0 0 0 1.97E+07 1.08E+07 - - - 1.3177 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.16281.16281.2 0.0585 20-Oct K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1 49169 16281 2 1245.769669 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3304.7 - 1.54E+06 - - - 0.9962 - 1.894 0.402 - 282.2 1 2 0 0.0012 11 0 0 0 5.30E+07 5.29E+07 - - - 3.7376 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.16287.16287.2 0.0242 18-Sep K.IPVSGPFLVK[136.11].T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1063.6521 1.27 49173 16287 2 1063.653217 532.8333 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3305.6 - 1.57E+06 - - - 1.0332 - 1.377 0.264 - 190.8 1 2 0 0.0011 10 0 0 0 1.65E+08 1.31E+08 - - - 1.8835 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.16289.16289.2 0.478 14-Sep R.LMGLEALK.S "sp|P48643|TCPE_HUMAN,tr|D6RIZ7|D6RIZ7_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0Y914|H0Y914_HUMAN" 4 873.4994 5.47 49174 16289 2 873.502661 437.757 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 3305.8 - 4.72E+07 - - - 3.7619 - 1.828 0.29 - 275.1 1 2 0 0.0033 8 0 0 0 2.01E+09 3.68E+08 - - - 3.0012 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.16299.16299.2 0.0213 16-Nov R.IGLINDMVR[166.11].F sp|Q14152|EIF3A_HUMAN 1 1039.5724 1.44 49182 16299 2 1039.574773 520.7935 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.84 3306.9 - 3.20E+06 - - - 2.3106 - 1.907 0.251 - 367.7 1 2 0 0.0024 9 0 0 0 1.09E+08 7.56E+07 - - - 2.7617 0.857 230117_WJC_METTL3_WT_vs_EV_F06.16302.16302.2 5.72 12-May R.TVVLLLR.L sp|Q9Y2C2|UST_HUMAN 1 812.5484 0.52 49185 16302 2 812.550373 407.2815 Uronyl 2-sulfotransferase OS=Homo sapiens OX=9606 GN=UST PE=2 SV=1 9.41 3307.3 - 490688 - - - 2.4602 - 0.949 0.001 - 57.8 1 2 0 0.002 7 0 0 0 5.74E+06 1.10E+07 - - - -1.1181 0.9432 230117_WJC_METTL3_WT_vs_EV_F06.16305.16305.2 0.634 12-Jul K.LMFEELR[166.11].N sp|Q9Y3I0|RTCB_HUMAN 1 946.4822 1.07 49186 16305 2 946.481772 474.2484 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.53 3307.6 - 2.13E+06 - - - -0.4089 - 1.102 0.049 - 135.8 1 2 0 -0.0004 7 0 0 0 1.25E+08 1.17E+08 - - - -0.2895 1 230117_WJC_METTL3_WT_vs_EV_F06.16308.16308.2 4.54E-05 22-Dec K.VLVALASEELAK[136.11].G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1249.7373 1.53 49189 16308 2 1249.737493 625.8759 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.53 3308 - 204702 - - - 0.1512 - 2.416 0.495 - 439.9 1 2 0 0.0002 12 0 0 0 5.13E+07 3.36E+07 - - - 5.018 0.9965 230117_WJC_METTL3_WT_vs_EV_F06.16311.16311.2 0.182 14-Jun R.EPLLTLVK[136.11].E sp|Q13200|PSMD2_HUMAN 1 919.5834 1.84 49190 16311 2 919.583547 460.799 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 6.1 3308.4 - 2.06E+06 - - - 0.1936 - 1.436 0.182 - 128.3 1 2 0 0.0002 8 0 0 0 2.24E+08 1.22E+08 - - - 1.4766 0.984 230117_WJC_METTL3_WT_vs_EV_F06.16313.16313.2 1.37 16-Aug K.VILTSPLIR[166.11].D sp|Q96SI9|STRBP_HUMAN 1 1020.6571 1.86 49192 16313 2 1020.65869 511.3358 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 9.72 3308.7 - 1.10E+06 - - - 1.5706 - 1.333 0.039 - 122.8 1 2 0 0.0016 9 0 0 0 4.88E+07 2.63E+07 - - - 0.1601 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.16318.16318.2 0.804 12-Jul K.LIIFDAR.Q "sp|Q13613|MTMR1_HUMAN,tr|Q8NEC6|Q8NEC6_HUMAN,tr|F8WA39|F8WA39_HUMAN,tr|H0YDX3|H0YDX3_HUMAN" 4 846.4963 3.88 49196 16318 2 846.498117 424.2554 Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4 5.84 3309.3 - 4.31E+06 - - - 2.1004 - 1.477 0.167 - 184.5 1 2 0 0.0018 7 0 0 0 8.81E+07 2.27E+07 - - - 1.5097 0.9965 230117_WJC_METTL3_WT_vs_EV_F06.16322.16322.2 0.246 12-Jun K.LWYTLDR.A sp|P00387|NB5R3_HUMAN 1 965.4971 2 49198 16322 2 965.49776 483.7558 NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3 5.84 3309.8 - 646782 - - - 0.7178 - 1.366 0.176 - 138.3 1 2 0 0.0007 7 0 0 0 5.81E+07 2.90E+07 - - - 1.3289 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.16326.16326.2 1.83E-05 22-Dec R.VFASELNAGIIK.T "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1260.7078 1.62 49200 16326 2 1260.711182 631.3612 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.97 3310.3 - 798201 - - - 2.6921 - 2.23 0.432 - 379.2 1 2 0 0.0034 12 0 0 0 1.48E+07 9.11E+06 - - - 4.3409 1 230117_WJC_METTL3_WT_vs_EV_F06.16328.16328.2 0.00276 20-Dec R.LLTGVEYVVGR.K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1204.6816 1.55 49201 16328 2 1204.684696 603.3481 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3310.5 - 1.38E+06 - - - 2.5924 - 2.515 0.501 - 417.6 1 2 0 0.0031 11 0 0 0 2.74E+07 1.76E+07 - - - 5.2354 1 230117_WJC_METTL3_WT_vs_EV_F06.16329.16329.2 2.13E-05 20-Oct R.LLTGVEYVVGR[166.11].K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1214.6898 1.56 49202 16329 2 1214.688282 608.3522 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3310.6 - 1.14E+06 - - - -1.2851 - 2.08 0.509 - 304.1 1 2 0 -0.0016 11 0 0 0 2.75E+07 1.77E+07 - - - 4.7812 0.9865 230117_WJC_METTL3_WT_vs_EV_F06.16334.16334.2 0.699 20-Jun K.VLEVPPVVYSR.Q "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1256.7129 0.63 49205 16334 2 1256.712654 629.3637 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 5.97 3311.2 - 0 - - - -0.1743 - 1.312 0.13 - 82.2 2 2 0 -0.0002 11 0 0 0 6.38E+06 1.01E+07 - - - 0.6013 1 230117_WJC_METTL3_WT_vs_EV_F06.16338.16338.2 0.000624 13/22 K.VLVALASEELAK.G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1241.7231 1.53 49206 16338 2 1241.724068 621.8688 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.53 3311.8 - 662265 - - - 0.7763 - 2.331 0.454 - 453.8 1 2 0 0.001 12 0 0 0 5.16E+07 3.36E+07 - - - 4.6207 0.9895 230117_WJC_METTL3_WT_vs_EV_F06.16352.16352.2 0.00353 12-Jun R.EAYYWLR[166.11].H sp|P46977|STT3A_HUMAN 1 1009.4897 1.43 49214 16352 2 1009.490643 505.7521 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6.1 3313.7 - 695337 - - - 0.947 - 1.166 0.126 - 130.1 1 2 0 0.001 7 0 0 0 5.15E+07 3.61E+07 - - - 0.458 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.16356.16356.2 0.00427 20-Oct R.VGASEAALFLK.K "sp|Q9UBC2|EP15R_HUMAN,tr|M0QX30|M0QX30_HUMAN,tr|K7EJR2|K7EJR2_HUMAN,tr|M0R1V5|M0R1V5_HUMAN,tr|M0R330|M0R330_HUMAN,tr|M0R165|M0R165_HUMAN" 6 1104.6179 0.4 49216 16356 2 1104.622861 553.3162 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 5.97 3314.2 - 428452 - - - 4.4821 - 2.093 0.392 - 240.1 1 2 0 0.005 11 0 0 0 9.72E+06 2.41E+07 - - - 3.9328 0.9827 230117_WJC_METTL3_WT_vs_EV_F06.16358.16358.2 0.0774 12-Jul R.EAYYWLR.H sp|P46977|STT3A_HUMAN 1 999.4814 1.4 49217 16358 2 999.480676 500.748 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6.1 3314.4 - 2.67E+06 - - - -0.7414 - 1.299 0.108 - 239.8 1 2 0 -0.0007 7 0 0 0 5.02E+07 3.59E+07 - - - 0.6673 0.9952 230117_WJC_METTL3_WT_vs_EV_F06.16359.16359.2 0.00399 12-Jun K.LWYTLDR[166.11].A sp|P00387|NB5R3_HUMAN 1 975.5053 1.99 49218 16359 2 975.504968 488.7599 NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3 5.84 3314.6 - 1.04E+06 - - - -0.3783 - 1.507 0.156 - 135.1 1 2 0 -0.0004 7 0 0 0 5.76E+07 2.89E+07 - - - 1.4926 0.9522 230117_WJC_METTL3_WT_vs_EV_F06.16360.16360.2 0.497 18-Sep K.LVALAVIDEK.N sp|Q96JJ7|TMX3_HUMAN 1 1069.6383 2.22 49219 16360 2 1069.634179 535.8264 Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2 4.37 3314.7 - 533096 - - - -3.863 - 1.599 0.138 - 127.7 1 2 0 -0.0041 10 0 0 0 1.28E+07 5.79E+06 - - - 1.3691 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.16362.16362.2 0.0046 14-Aug K.VTNLLMLK.G "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|B4DI28|B4DI28_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|X6R242|X6R242_HUMAN,tr|A0A6Q8PH43|A0A6Q8PH43_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 18 930.5572 1.19 49220 16362 2 930.557879 466.2859 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.72 3314.9 - 1.09E+07 - - - 0.7039 - 1.84 0.311 - 217.6 1 2 0 0.0007 8 0 0 0 4.80E+08 4.03E+08 - - - 3.1769 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.16364.16364.2 0.218 12-Jul K.LWVLETK[136.11].E "sp|Q15061|WDR43_HUMAN,tr|C9JEE7|C9JEE7_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 3 895.5259 8.11 49222 16364 2 895.526071 448.7702 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3315 - 805365 - - - 0.2423 - 1.502 0.205 - 179.9 1 2 0 0.0002 7 0 0 0 3.23E+08 3.99E+07 - - - 1.844 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.16366.16366.2 13 12-Sep M.LPLSLLK.T "sp|Q9Y4Z0|LSM4_HUMAN,sp|Q969I6|S38A4_HUMAN,tr|F8VQY9|F8VQY9_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 5 782.5266 568.34 49223 16366 2 782.526924 392.2706 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 8.75 3315.2 - 947648 - - - 0.4447 - 1.972 0.071 - 268.9 1 2 0 0.0003 7 0 0 0 5.28E+08 9.29E+05 - - - 1.7169 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.16380.16380.2 0.00617 20-Oct K.VLEVPPVVYSR[166.11].Q "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1266.7211 0.61 49232 16380 2 1266.721918 634.3678 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 5.97 3317 - 141212 - - - 0.6118 - 2.209 0.373 - 357.1 1 2 0 0.0008 11 0 0 0 6.47E+06 1.07E+07 - - - 3.9397 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.16393.16393.2 0.0625 12-Aug K.FVSFLGR[166.11].T "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 834.4627 1.91 49242 16393 2 834.462878 418.2386 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 9.75 3318.5 - 716382 - - - 0.1606 - 1.485 0.278 - 211.1 1 2 0 0.0001 7 0 0 0 3.74E+08 1.96E+08 - - - 2.3472 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.16398.16398.2 0.00133 14-Aug K.VIFLENYR.V "sp|P06737|PYGL_HUMAN,sp|P11217|PYGM_HUMAN,sp|P11216|PYGB_HUMAN,tr|E9PK47|E9PK47_HUMAN,tr|H0Y4Z6|H0Y4Z6_HUMAN" 5 1052.5655 4.67 49245 16398 2 1052.566707 527.29 "Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL PE=1 SV=4" 5.97 3319.1 - 3.10E+06 - - - 1.1648 - 1.871 0.436 - 253.9 1 2 0 0.0012 8 0 0 0 6.79E+07 1.45E+07 - - - 4.1503 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16401.16401.2 0.268 20-Oct R.IDALLAVDPPR.A sp|P50219|MNX1_HUMAN 1 1178.6659 2.07 49248 16401 2 1178.6664 590.3402 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3319.4 - 709741 - - - 0.4047 - 2.423 0.304 - 304.9 1 2 0 0.0005 11 0 0 0 2.51E+07 1.21E+07 - - - 3.6803 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.16403.16403.2 0.0339 16-Aug R.SPVYLTVLK[136.11].H "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1026.6205 1.41 49250 16403 2 1026.621306 514.3175 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 8.31 3319.7 - 576784 - - - 0.8017 - 1.698 0.277 - 197.9 1 2 0 0.0008 9 0 0 0 1.55E+07 1.10E+07 - - - 2.6184 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.16405.16405.2 0.00383 20-Sep R.IDALLAVDPPR[166.11].A sp|P50219|MNX1_HUMAN 1 1188.6742 2.08 49252 16405 2 1188.678246 595.3444 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3319.9 - 327630 - - - 3.4097 - 1.99 0.14 - 258 1 2 0 0.0041 11 0 0 0 2.49E+07 1.20E+07 - - - 1.9353 1 230117_WJC_METTL3_WT_vs_EV_F06.16408.16408.2 1.53E-07 13/22 K.LNDLEEALQQAK.E sp|P35908|K22E_HUMAN 1 1370.7042 999 49255 16408 2 1370.704325 686.3594 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3320.3 - 173372 - - - 0.1211 - 2.631 0.442 - 767 1 2 0 0.0002 12 0 0 0 1.48E+06 0.00E+00 - - - 4.8509 0.9923 230117_WJC_METTL3_WT_vs_EV_F06.16409.16409.2 0.817 16-Jul K.YIIEELNVR[166.11].K "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1157.632 38.17 49256 16409 2 1157.631625 579.8233 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.53 3320.4 - 146601 - - - -0.3188 - 1.27 0.182 - 87 1 2 0 -0.0004 9 0 0 0 1.10E+08 2.89E+06 - - - 1.0766 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.16414.16414.2 0.000116 18-Oct K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 22.26 49260 16414 2 1146.628718 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3321.1 - 2.02E+06 - - - 0.2119 - 2.048 0.463 - 283.9 1 2 0 0.0002 10 0 0 0 2.02E+08 9.07E+06 - - - 4.4616 0.9905 230117_WJC_METTL3_WT_vs_EV_F06.16418.16418.2 0.049 16-Sep R.SLFVVVGDR[166.11].G "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 1000.5581 -1 49264 16418 2 1000.563791 501.2863 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.55 3321.4 - 1.28E+06 - - - 5.6868 - 1.736 0.259 - 397.7 1 2 0 0.0057 9 0 0 0 0.00E+00 0.00E+00 - - - 2.5479 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.16419.16419.2 0.000406 16-Aug R.SLFVVVGDR.G "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 990.5498 0.34 49265 16419 2 990.55112 496.2822 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.55 3321.5 - 1.06E+06 - - - 1.3013 - 1.883 0.452 - 314.7 1 2 0 0.0013 9 0 0 0 1.67E+07 4.98E+07 - - - 4.21 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.16421.16421.2 0.00154 16-Aug K.GLIDYETFK.E sp|P15924|DESP_HUMAN 1 1084.5441 4.82 49267 16421 2 1084.54424 543.2793 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3321.7 - 245574 - - - 0.1503 - 1.736 0.37 - 143.8 1 2 0 0.0002 9 0 0 0 6.14E+06 1.27E+06 - - - 3.3695 0.998 230117_WJC_METTL3_WT_vs_EV_F06.16425.16425.2 4.72 14-Jul R.ALDIPLVK[136.11].N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 875.5572 1.35 49269 16425 2 875.55795 438.7859 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3322.2 - 907359 - - - 0.9091 - 1.426 0.221 - 150.1 1 2 0 0.0008 8 0 0 0 1.66E+08 1.24E+08 - - - 1.7433 0.8981 230117_WJC_METTL3_WT_vs_EV_F06.16426.16426.2 0.0304 12-Jul Q.AAILHLK[136.11].R "sp|Q68DA7|FMN1_HUMAN,sp|Q8NHP7|EXD1_HUMAN,tr|H0YM30|H0YM30_HUMAN,tr|A0A5F9ZHS8|A0A5F9ZHS8_HUMAN" 4 772.5051 1.86 49270 16426 2 772.506903 387.2598 Formin-1 OS=Homo sapiens OX=9606 GN=FMN1 PE=1 SV=3 8.8 3322.3 - 1.14E+06 - - - 2.387 - 1.341 0.314 - 214 1 1 0 0.0018 7 0 0 0 9.03E+07 4.85E+07 - - - 2.2893 1 230117_WJC_METTL3_WT_vs_EV_F06.16435.16435.2 0.000263 16-Sep K.GPLMMYISK.M sp|P13639|EF2_HUMAN 1 1038.5242 0.1 49278 16435 2 1038.526822 520.2694 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 3323.5 - 1.55E+06 - - - 2.5151 - 2.047 0.471 - 377.5 1 2 0 0.0026 9 0 0 0 4.58E+07 4.55E+08 - - - 4.5915 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.16438.16438.2 0.141 14-Aug R.ALDIPLVK.N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 867.543 1.24 49281 16438 2 867.544423 434.7788 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3323.7 - 921345 - - - 1.6933 - 1.587 0.238 - 227.9 1 2 0 0.0015 8 0 0 0 9.69E+07 7.82E+07 - - - 2.1913 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.16443.16443.2 0.399 14-Jul K.VIILSLDR.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 927.5753 2.38 49284 16443 2 927.577155 464.7949 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.81 3324.3 - 4.08E+06 - - - 1.9815 - 1.677 0.295 - 196.5 1 2 0 0.0018 8 0 0 0 2.28E+08 9.56E+07 - - - 2.7786 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16444.16444.2 0.000671 12-Jul K.YYTLFGR.S sp|P07814|SYEP_HUMAN 1 918.46 1.18 49285 16444 2 918.46122 460.2373 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.59 3324.3 - 1.52E+06 - - - 1.3795 - 1.551 0.389 - 137.8 1 2 0 0.0013 7 0 0 0 1.03E+08 8.71E+07 - - - 3.3044 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.16445.16445.2 0.0191 18-Jul K.AAPEMVSLLK.R "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN,tr|K7EQ99|K7EQ99_HUMAN" 3 1057.5842 1.22 49286 16445 2 1057.585962 529.7994 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 6.05 3324.4 - 979888 - - - 1.6973 - 1.381 0.369 - 154.3 1 2 0 0.0018 10 0 0 0 5.29E+07 4.32E+07 - - - 2.6669 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.16450.16450.2 0.00126 18-Aug K.AAPEMVSLLK[136.11].R "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN,tr|K7EQ99|K7EQ99_HUMAN" 3 1065.5984 1.22 49289 16450 2 1065.600411 533.8065 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 6.05 3325 - 1.40E+06 - - - 1.9182 - 1.528 0.463 - 181 1 2 0 0.002 10 0 0 0 5.29E+07 4.32E+07 - - - 3.6435 1 230117_WJC_METTL3_WT_vs_EV_F06.16451.16451.2 1.95E-05 16-Sep K.GPLMMYISK[136.11].M sp|P13639|EF2_HUMAN 1 1046.5384 1.55 49290 16451 2 1046.539789 524.2765 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 3325.1 - 606280 - - - 1.3177 - 1.874 0.538 - 315.1 1 2 0 0.0014 9 0 0 0 2.97E+07 1.91E+07 - - - 4.8313 1 230117_WJC_METTL3_WT_vs_EV_F06.16453.16453.2 1.73E-05 13/26 F.LLIGGGTAAFAAAR.S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1287.7299 6.24 49292 16453 2 1287.73328 644.8722 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3325.4 - 417660 - - - 2.6092 - 2.36 0.577 - 531.1 1 1 0 0.0034 14 0 0 0 1.46E+07 2.34E+06 - - - 5.4564 0.999 230117_WJC_METTL3_WT_vs_EV_F06.16460.16460.2 0.0374 14-Aug K.VIILSLDR[166.11].S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 937.5836 2.38 49298 16460 2 937.586446 469.7991 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.81 3326.3 - 7.50E+06 - - - 3.0493 - 1.796 0.324 - 232.3 1 2 0 0.0029 8 0 0 0 2.28E+08 9.56E+07 - - - 3.1992 0.9744 230117_WJC_METTL3_WT_vs_EV_F06.16461.16461.2 0.647 16-Jun R.LVLQYAPSA.- "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN" 2 960.528 - 49299 16461 2 960.531014 481.2713 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 5.52 3326.4 - 3.65E+06 - - - 3.1035 - 1.319 0.088 - 83.1 3 2 0 0.003 9 0 0 0 - - - - - 0.2779 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.16462.16462.2 0.00491 12-Aug R.SFDLLVK[136.11].N sp|Q9HB71|CYBP_HUMAN 1 828.4837 2.15 49300 16462 2 828.484601 415.2491 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 5.55 3326.5 - 2.44E+06 - - - 1.1418 - 1.46 0.326 - 201.9 1 2 0 0.0009 7 0 0 0 1.46E+08 6.80E+07 - - - 2.6476 0.982 230117_WJC_METTL3_WT_vs_EV_F06.16464.16464.2 0.89 12-Aug K.LPLLLSR.M "sp|P49902|5NTC_HUMAN,sp|O95866|G6B_HUMAN,tr|A0A140T9L8|A0A140T9L8_HUMAN,tr|A0A6Q8PHB5|A0A6Q8PHB5_HUMAN,tr|A0A140T9V1|A0A140T9V1_HUMAN,tr|A0A6Q8PHP0|A0A6Q8PHP0_HUMAN,tr|B7ZLJ5|B7ZLJ5_HUMAN,tr|A0A0G2JJG8|A0A0G2JJG8_HUMAN,tr|F8WDG3|F8WDG3_HUMAN,tr|Q5JUV4|Q5JUV4_HUMAN" 10 810.5327 0.73 49302 16464 2 810.536157 406.2736 Cytosolic purine 5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5C2 PE=1 SV=1 9.75 3326.7 - 586777 - - - 4.2355 - 1.651 0.06 - 308.2 1 2 0 0.0034 7 0 0 0 1.82E+07 2.51E+07 - - - 1.0717 0.9667 230117_WJC_METTL3_WT_vs_EV_F06.16466.16466.2 0.0239 26-Sep F.LLIGGGTAAFAAAR[166.11].S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1297.7382 6.24 49304 16466 2 1297.738615 649.8764 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3327 - 171962 - - - 0.3275 - 1.966 0.418 - 180.8 1 1 0 0.0004 14 0 0 0 1.46E+07 2.34E+06 - - - 3.8246 0.9713 230117_WJC_METTL3_WT_vs_EV_F06.16472.16472.2 1.71 12-Jul K.YYTLFGR[166.11].S sp|P07814|SYEP_HUMAN 1 928.4682 1.17 49308 16472 2 928.470792 465.2414 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.59 3327.7 - 5.49E+06 - - - 2.7669 - 1.174 0.07 - 163.9 1 2 0 0.0026 7 0 0 0 1.03E+08 8.75E+07 - - - 0.0655 0.9845 230117_WJC_METTL3_WT_vs_EV_F06.16476.16476.2 2.04 16-Aug R.ALAYFEQLK.L "sp|O43592|XPOT_HUMAN,tr|F5GYW6|F5GYW6_HUMAN,tr|F8WDU6|F8WDU6_HUMAN" 3 1081.5808 3.88 49312 16476 2 1081.583527 541.7977 Exportin-T OS=Homo sapiens OX=9606 GN=XPOT PE=1 SV=2 6.05 3328.1 - 225768 - - - 2.5241 - 1.347 0.067 - 154.8 1 2 0 0.0027 9 0 0 0 8.02E+06 2.07E+06 - - - 0.3968 0.9902 230117_WJC_METTL3_WT_vs_EV_F06.16480.16480.2 1.15 14-Aug K.LLELLPGK[136.11].V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 889.5728 2.2 49314 16480 2 889.57564 445.7937 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3328.6 - 1.14E+06 - - - 3.1869 - 1.175 0.201 - 153.6 1 2 0 0.0028 8 0 0 0 1.12E+08 5.11E+07 - - - 1.0111 0.997 230117_WJC_METTL3_WT_vs_EV_F06.16481.16481.2 0.16 16-Jul R.IGGISGIFK[136.11].S sp|Q9UK59|DBR1_HUMAN 1 898.5368 1.19 49315 16481 2 898.539605 450.2757 Lariat debranching enzyme OS=Homo sapiens OX=9606 GN=DBR1 PE=1 SV=2 8.75 3328.8 - 684703 - - - 3.174 - 1.482 0.247 - 65.3 1 2 0 0.0029 9 0 0 0 2.53E+07 2.11E+07 - - - 2.0026 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.16484.16484.2 0.00141 16-Aug K.NAIVVLIPK[136.11].Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 973.6416 2.21 49318 16484 2 973.643572 487.8281 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3329.2 - 425389 - - - 2.0737 - 1.355 0.429 - 105.1 1 2 0 0.002 9 0 0 0 2.01E+08 9.08E+07 - - - 3.0879 0.9953 230117_WJC_METTL3_WT_vs_EV_F06.16485.16485.2 0.00229 24-Jul K.FGNEVIPVTVTVK.G "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1401.7868 16.7 49319 16485 2 1401.79323 701.9007 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 6 3329.3 - 222793 - - - 4.6105 - 1.623 0.302 - 125.3 1 2 0 0.0065 13 0 0 0 1.54E+06 9.25E+04 - - - 2.5125 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.16495.16495.2 0.0573 16-Oct K.NAIVVLIPK.Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 965.6274 2.21 49325 16495 2 965.629466 483.821 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3330.6 - 690965 - - - 2.1882 - 1.904 0.427 - 332.7 1 2 0 0.0021 9 0 0 0 2.01E+08 9.08E+07 - - - 4.0572 0.9803 230117_WJC_METTL3_WT_vs_EV_F06.16496.16496.2 0.158 20-Jun R.LVMELSGEMVR.K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1262.6363 2.43 49326 16496 2 1262.640602 632.3254 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3330.8 - 257686 - - - 3.4238 - 1.172 0.153 - 53.6 1 2 0 0.0043 11 0 0 0 1.31E+07 5.40E+06 - - - 0.5991 0.951 230117_WJC_METTL3_WT_vs_EV_F06.16498.16498.2 0.466 20-May R.LVMELSGEMVR[166.11].K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1272.6445 2.42 49328 16498 2 1272.645331 637.3296 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3331 - 121642 - - - 0.6145 - 1.275 0.023 - 68.7 7 2 0 0.0008 11 0 0 0 1.31E+07 5.40E+06 - - - -0.5096 0.9936 230117_WJC_METTL3_WT_vs_EV_F06.16502.16502.2 0.435 12-Jun K.NLFELAR.Q "sp|Q9UN37|VPS4A_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 2 861.4709 3.36 49330 16502 2 861.472899 431.7427 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 6 3331.6 - 1.84E+06 - - - 2.3762 - 1.275 0.159 - 158.2 1 2 0 0.002 7 0 0 0 5.28E+07 1.57E+07 - - - 0.9845 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.16503.16503.2 0.041 16-Aug R.LIPDFPVAR.S sp|Q96S55|WRIP1_HUMAN 1 1026.5862 7.36 49331 16503 2 1026.587855 514.3004 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 5.84 3331.7 - 848276 - - - 1.5966 - 1.52 0.254 - 200.9 1 2 0 0.0016 9 0 0 0 5.61E+07 7.63E+06 - - - 2.1279 1 230117_WJC_METTL3_WT_vs_EV_F06.16504.16504.2 9.63E-05 20-Dec K.NALESYAFNMK.S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1286.5965 17.8 49332 16504 2 1286.599946 644.3055 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3331.8 - 734737 - - - 2.6605 - 2.477 0.465 - 551 1 2 0 0.0034 11 0 0 0 2.65E+07 1.49E+06 - - - 4.9282 0.998 230117_WJC_METTL3_WT_vs_EV_F06.16505.16505.2 0.00738 14-Aug K.SIILEGFK.S sp|O95347|SMC2_HUMAN 1 905.5222 0.51 49333 16505 2 905.525073 453.7684 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 5.72 3332 - 248656 - - - 3.1518 - 1.376 0.321 - 145.3 1 2 0 0.0029 8 0 0 0 6.17E+06 1.20E+07 - - - 2.3736 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.16509.16509.2 0.144 14-Oct K.LLELLPGK.V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 881.5586 2.2 49335 16509 2 881.560729 441.7866 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3332.5 - 4.12E+06 - - - 2.4094 - 1.947 0.18 - 337.5 1 2 0 0.0021 8 0 0 0 1.12E+08 5.11E+07 - - - 2.3793 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.16516.16516.2 0.037 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.13 49340 16516 2 1235.763109 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3333.3 - 650896 - - - 2.388 - 1.874 0.337 - 212.9 1 2 0 0.003 11 0 0 0 8.85E+07 7.86E+07 - - - 3.2282 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.16517.16517.2 0.00119 16-Aug R.FLIIDEADR.M sp|Q8N8A6|DDX51_HUMAN 1 1090.5659 1.3 49341 16517 2 1090.570409 546.2902 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 4.03 3333.4 - 1.03E+06 - - - 4.1575 - 1.632 0.395 - 203.1 1 2 0 0.0045 9 0 0 0 3.07E+07 2.36E+07 - - - 3.3741 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.16518.16518.2 0.0154 16-Sep K.FGLFTPGSR.L "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 980.508 0.7 49342 16518 2 980.511303 491.2613 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 9.75 3333.4 - 5.58E+06 - - - 3.4033 - 1.842 0.376 - 307.1 1 2 0 0.0033 9 0 0 0 1.64E+08 2.34E+08 - - - 3.5843 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.16525.16525.2 0.00228 16-Oct R.LLQSLLDTR.C sp|Q13045|FLII_HUMAN 1 1057.6132 1.37 49347 16525 2 1057.615626 529.8139 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3334.2 - 951110 - - - 2.3326 - 1.833 0.356 - 325.7 1 2 0 0.0025 9 0 0 0 1.45E+07 1.06E+07 - - - 3.4227 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.16529.16529.2 0.631 14-Aug K.ALDYYMLR.N sp|Q9Y490|TLN1_HUMAN 1 1043.511 3.13 49350 16529 2 1043.510996 522.7628 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.88 3334.7 - 317132 - - - -0.0057 - 1.504 0.209 - 200.2 1 2 0 0 8 0 0 0 2.57E+07 8.22E+06 - - - 1.8156 0.9569 230117_WJC_METTL3_WT_vs_EV_F06.16531.16531.2 0.237 20-Jun K.NALESYAFNMK[136.11].S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1294.6107 17.8 49352 16531 2 1294.616126 648.3126 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3334.9 - 70029.1 - - - 4.1735 - 1.051 0.165 - 75.6 1 2 0 0.0054 11 0 0 0 2.65E+07 1.49E+06 - - - 0.3926 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16533.16533.2 0.00191 20-Sep K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.15 49353 16533 2 1245.771432 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3335.1 - 480982 - - - 2.4114 - 1.77 0.402 - 159.9 1 2 0 0.003 11 0 0 0 8.50E+07 7.37E+07 - - - 3.5539 0.9853 230117_WJC_METTL3_WT_vs_EV_F06.16535.16535.2 0.454 12-Jul K.AILFVPR.R "sp|Q9NQH7|XPP3_HUMAN,sp|P07900|HS90A_HUMAN" 2 814.5065 1.79 49354 16535 2 814.507176 408.2605 Xaa-Pro aminopeptidase 3 OS=Homo sapiens OX=9606 GN=XPNPEP3 PE=1 SV=1 9.79 3335.4 - 7.45E+06 - - - 0.8189 - 1.463 0 - 259.3 1 2 0 0.0007 7 0 0 0 6.98E+08 3.91E+08 - - - 0.2464 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.16548.16548.2 0.0601 20-Nov K.LISSVDPQFLK.L "sp|Q9BVG4|PBDC1_HUMAN,tr|A6NDF3|A6NDF3_HUMAN" 2 1245.6969 20.7 49363 16548 2 1245.699568 623.8557 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 5.84 3337.1 - 1.91E+06 - - - 2.1506 - 1.501 0.309 - 246.6 1 2 0 0.0027 11 0 0 0 4.35E+07 2.10E+06 - - - 2.4211 0.997 230117_WJC_METTL3_WT_vs_EV_F06.16557.16557.2 0.0425 20-Aug K.LISSVDPQFLK[136.11].L "sp|Q9BVG4|PBDC1_HUMAN,tr|A6NDF3|A6NDF3_HUMAN" 2 1253.7111 20.7 49370 16557 2 1253.711006 627.8628 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 5.84 3338.3 - 434168 - - - -0.0662 - 1.241 0.285 - 145.9 1 2 0 -0.0001 11 0 0 0 4.35E+07 2.10E+06 - - - 1.7301 0.9836 230117_WJC_METTL3_WT_vs_EV_F06.16572.16572.2 2.92 12-Jun R.DLIDYVR.Y "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 892.4654 2.05 49378 16572 2 892.466397 447.24 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.21 3340.1 - 1.98E+06 - - - 1.0813 - 1.104 0.107 - 139 1 2 0 0.001 7 0 0 0 8.06E+07 3.93E+07 - - - 0.1445 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16611.16611.2 0.00456 14-Oct R.IPQLLLER[166.11].Y "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 990.6101 1.07 49385 16611 2 990.610751 496.3123 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 6 3345.9 - 5.15E+06 - - - 0.6208 - 1.917 0.341 - 492.4 1 2 0 0.0006 8 0 0 0 1.26E+08 1.17E+08 - - - 3.5221 1 230117_WJC_METTL3_WT_vs_EV_F06.16613.16613.2 1.11E-06 22-Dec K.VFGAAPLENVVR.K "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 1270.7034 3.95 49387 16613 2 1270.701792 636.359 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 5.97 3346.1 - 2.24E+06 - - - -1.2426 - 2.334 0.48 - 392.7 1 2 0 -0.0016 12 0 0 0 1.00E+08 2.53E+07 - - - 4.8159 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.16622.16622.2 0.00444 18-Sep K.IFFAGDTIPK[136.11].S "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 5 1115.6106 1.87 49389 16622 2 1115.610288 558.8126 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.84 3347.5 - 0 - - - -0.3218 - 1.642 0.282 - 147.2 1 2 0 -0.0004 10 0 0 0 7.04E+07 3.77E+07 - - - 2.508 0.9879 230117_WJC_METTL3_WT_vs_EV_F06.16630.16630.2 0.287 14-Aug R.VAFTLLEK.V "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 4 919.5379 7.59 49392 16630 2 919.535608 460.7762 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 5.97 3348.5 - 679893 - - - -2.4588 - 1.434 0.23 - 201.1 1 2 0 -0.0023 8 0 0 0 6.92E+07 9.12E+06 - - - 1.8262 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.16631.16631.2 0.00783 18-Sep K.FAYVPFGAGR.H "sp|Q16850|CP51A_HUMAN,tr|H7C0D0|H7C0D0_HUMAN" 2 1083.5502 2.82 49393 16631 2 1083.552216 542.7824 Lanosterol 14-alpha demethylase OS=Homo sapiens OX=9606 GN=CYP51A1 PE=1 SV=4 8.75 3348.7 - 1.35E+06 - - - 1.8929 - 1.642 0.3 - 255.7 1 2 0 0.0021 10 0 0 0 2.45E+07 8.69E+06 - - - 2.6404 0.9608 230117_WJC_METTL3_WT_vs_EV_F06.16632.16632.2 0.291 18-Jul K.FAYVPFGAGR[166.11].H "sp|Q16850|CP51A_HUMAN,tr|H7C0D0|H7C0D0_HUMAN" 2 1093.5584 2.71 49394 16632 2 1093.563475 547.7865 Lanosterol 14-alpha demethylase OS=Homo sapiens OX=9606 GN=CYP51A1 PE=1 SV=4 8.75 3348.8 - 728130 - - - 4.6088 - 1.062 0.198 - 108.2 1 2 0 0.005 10 0 0 0 2.33E+07 8.58E+06 - - - 0.6698 0.9823 230117_WJC_METTL3_WT_vs_EV_F06.16635.16635.2 0.201 12-Jun K.ELLIFNK[136.11].Q "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 883.5259 1.1 49395 16635 2 883.527416 442.7702 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.1 3349.2 - 2.34E+06 - - - 1.7679 - 1.376 0.008 - 128.3 1 2 0 0.0016 7 0 0 0 5.62E+08 5.09E+08 - - - 0.1109 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16642.16642.2 0.0132 24-Sep K.VLIIGGGDGGVLR.E "sp|P19623|SPEE_HUMAN,tr|K7ESL0|K7ESL0_HUMAN" 2 1224.719 36.18 49398 16642 2 1224.72037 613.3668 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.81 3350 - 0 - - - 1.1015 - 1.693 0.371 - 215.1 1 2 0 0.0013 13 0 0 0 7.22E+07 1.99E+06 - - - 3.1321 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.16654.16654.2 0.221 14-Jun R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 8730.24 49403 16654 2 1000.56099 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3351.6 - 4.68E+09 - - - 1.6561 - 1.421 0.278 - 116.4 1 2 0 0.0017 8 0 0 0 4.88E+11 5.59E+07 - - - 2.1535 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.16660.16660.2 0.000133 18-Sep R.LYLINSPVVR[166.11].A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1182.7 1.49 49405 16660 2 1182.699339 592.3573 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3352.5 - 1.29E+06 - - - -0.5707 - 1.99 0.269 - 305 1 2 0 -0.0007 10 0 0 0 3.82E+08 2.57E+08 - - - 2.9484 1 230117_WJC_METTL3_WT_vs_EV_F06.16670.16670.2 7.91E-08 22-Dec R.GYISPYFINTSK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1388.6976 2.65 49409 16670 2 1388.696856 695.3561 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3353.8 - 1.39E+06 - - - -0.548 - 2.465 0.505 - 541.1 1 2 0 -0.0008 12 0 0 0 5.85E+07 2.20E+07 - - - 5.1445 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.16679.16679.2 0.000643 18-Sep R.LYLINSPVVR.A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1172.6917 1.49 49412 16679 2 1172.693523 587.3531 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3355 - 1.88E+06 - - - 1.517 - 1.973 0.25 - 354.8 1 2 0 0.0018 10 0 0 0 3.82E+08 2.57E+08 - - - 2.7838 0.8554 230117_WJC_METTL3_WT_vs_EV_F06.16681.16681.2 2.89 12-Jun K.QLWSSSK.G "sp|Q8N8U2|CDYL2_HUMAN,tr|A0A0B4J291|A0A0B4J291_HUMAN" 2 834.4236 63.96 49414 16681 2 834.4225 418.2191 Chromodomain Y-like protein 2 OS=Homo sapiens OX=9606 GN=CDYL2 PE=1 SV=2 8.75 3355.3 - 0 - - - -1.2799 - 0.964 0.084 - 91.5 2 2 0 -0.0011 7 0 0 0 3.47E+07 5.42E+05 - - - -0.5896 0.9799 230117_WJC_METTL3_WT_vs_EV_F06.16682.16682.2 0.00198 12-Jul K.FTVPMLK[136.11].E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 842.4815 0.83 49415 16682 2 842.478734 422.248 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3355.4 - 0 - - - -3.3389 - 1.466 0.217 - 161.7 1 2 0 -0.0028 7 0 0 0 3.93E+07 4.72E+07 - - - 1.855 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.16686.16686.2 0.00107 18-Sep R.GTPLISPLIK.W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1037.6485 1.7 49417 16686 2 1037.645589 519.8315 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3355.9 - 3.34E+06 - - - -2.788 - 1.68 0.421 - 342.9 1 2 0 -0.0029 10 0 0 0 1.70E+08 9.99E+07 - - - 3.5977 0.9931 230117_WJC_METTL3_WT_vs_EV_F06.16691.16691.2 0.901 14-Oct K.IPLGLDLK.N "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 867.543 1.46 49419 16691 2 867.544013 434.7788 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.84 3356.5 - 1.35E+06 - - - 1.2207 - 1.591 0.04 - 329 1 2 0 0.0011 8 0 0 0 1.02E+08 6.97E+07 - - - 0.7366 1 230117_WJC_METTL3_WT_vs_EV_F06.16695.16695.2 1.36E-05 18-Dec R.VAAAVDLIIK.S "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1011.6328 1.57 49421 16695 2 1011.633267 506.8237 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3356.9 - 4.58E+06 - - - 0.43 - 2.51 0.489 - 451.5 1 2 0 0.0004 10 0 0 0 6.98E+07 4.46E+07 - - - 5.2214 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.16697.16697.2 0.00113 18-Aug R.GTPLISPLIK[136.11].W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1045.6627 1.7 49422 16697 2 1045.660188 523.8386 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3357.2 - 3.11E+06 - - - -2.3851 - 1.597 0.444 - 204.6 1 2 0 -0.0025 10 0 0 0 1.70E+08 9.99E+07 - - - 3.6263 0.9932 230117_WJC_METTL3_WT_vs_EV_F06.16699.16699.2 0.00585 18-Sep R.TLGGLEMELR.L "sp|Q9Y4L1|HYOU1_HUMAN,tr|A0A087WWI4|A0A087WWI4_HUMAN,tr|K7EQK2|K7EQK2_HUMAN,tr|A0A494C039|A0A494C039_HUMAN,tr|A0A087X054|A0A087X054_HUMAN,tr|E9PJ21|E9PJ21_HUMAN" 6 1117.5801 0.43 49423 16699 2 1117.576038 559.7973 Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1 4.53 3357.4 - 637581 - - - -3.6749 - 1.568 0.409 - 143.2 1 2 0 -0.0041 10 0 0 0 6.31E+06 1.46E+07 - - - 3.3161 1 230117_WJC_METTL3_WT_vs_EV_F06.16701.16701.2 2.86E-05 18-Nov R.YGLAAAVFTR.D sp|P30837|AL1B1_HUMAN 1 1067.5764 3.5 49424 16701 2 1067.575416 534.7955 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 8.75 3357.6 - 1.10E+06 - - - -0.903 - 2.285 0.516 - 403.1 1 2 0 -0.001 10 0 0 0 4.04E+07 1.15E+07 - - - 5.1585 0.9947 230117_WJC_METTL3_WT_vs_EV_F06.16707.16707.2 1.42 16-Jul K.GSLLPTSPR.L "tr|H7C179|H7C179_HUMAN,tr|H7C128|H7C128_HUMAN,tr|H7C127|H7C127_HUMAN" 3 926.5185 1.37 49427 16707 2 926.519388 464.2665 Bromodomain-containing protein 8 (Fragment) OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=1 9.75 3358.4 - 529969 - - - 0.925 - 1.373 0.135 - 144.9 1 2 0 0.0009 9 0 0 0 1.34E+08 9.78E+07 - - - 0.9549 1 230117_WJC_METTL3_WT_vs_EV_F06.16714.16714.2 8.30E-06 20-Dec R.FGGLVLSPVGK.Q sp|Q9UJK0|TSR3_HUMAN 1 1072.6281 1.39 49431 16714 2 1072.631973 537.3213 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.75 3359.3 - 1.61E+06 - - - 3.6285 - 2.322 0.537 - 501.6 1 2 0 0.0039 11 0 0 0 3.64E+07 2.62E+07 - - - 5.285 0.9919 230117_WJC_METTL3_WT_vs_EV_F06.16717.16717.2 0.0191 12-Jun K.LMIWDTR.S "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 933.4742 1.28 49432 16717 2 933.478205 467.7444 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3359.7 - 1.04E+06 - - - 4.2658 - 1.34 0.241 - 190.1 1 2 0 0.004 7 0 0 0 1.68E+08 1.31E+08 - - - 1.7471 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.16719.16719.2 0.00415 14-Jul R.QVFLATWK.D "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 991.5491 0 49434 16719 2 991.551465 496.7818 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.75 3359.9 - 762307 - - - 2.3831 - 1.443 0.357 - 165.3 1 2 0 0.0024 8 0 0 0 1.94E+07 2.15E+10 - - - 2.7831 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.16725.16725.2 0.0884 12-Jul K.FTVPMLK.E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 834.4673 0.83 49438 16725 2 834.46713 418.2409 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3360.7 - 1.24E+06 - - - -0.26 - 1.177 0.315 - 186.4 1 2 0 -0.0002 7 0 0 0 3.93E+07 4.72E+07 - - - 1.8839 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.16726.16726.2 0.000686 20-Nov R.FGGLVLSPVGK[136.11].Q sp|Q9UJK0|TSR3_HUMAN 1 1080.6423 1.46 49439 16726 2 1080.647546 541.3284 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.75 3360.8 - 891962 - - - 4.8721 - 2.076 0.451 - 364.2 1 2 0 0.0053 11 0 0 0 3.63E+07 2.48E+07 - - - 4.3465 0.9848 230117_WJC_METTL3_WT_vs_EV_F06.16728.16728.2 0.0122 14-Aug K.LGPLAFYK.G "sp|Q9UBX3|DIC_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 907.5167 2.15 49441 16728 2 907.520062 454.7656 Mitochondrial dicarboxylate carrier OS=Homo sapiens OX=9606 GN=SLC25A10 PE=1 SV=2 8.59 3361 - 458231 - - - 3.6605 - 1.491 0.089 - 126.9 1 2 0 0.0033 8 0 0 0 3.61E+07 1.68E+07 - - - 0.902 0.9772 230117_WJC_METTL3_WT_vs_EV_F06.16733.16733.2 2.03 12-Jun R.ILLQYLK.Q "sp|Q9P0U3|SENP1_HUMAN,sp|Q9NVH2|INT7_HUMAN" 2 889.5637 4.58 49444 16733 2 889.565544 445.7891 Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2 8.59 3361.6 - 1.15E+06 - - - 2.0842 - 1.173 0.08 - 104.6 2 2 0 0.0019 7 0 0 0 1.83E+07 4.00E+06 - - - 0.0024 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.16734.16734.2 0.217 12-Jul R.FVAELWK.D sp|P35580|MYH10_HUMAN 1 891.4854 0.74 49445 16734 2 891.487964 446.75 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3361.8 - 1.15E+06 - - - 2.8312 - 1.424 0.212 - 155.1 1 2 0 0.0025 7 0 0 0 4.42E+07 6.01E+07 - - - 1.726 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.16735.16735.2 0.00909 16-Sep R.GLFTGLTPR.L "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 960.5393 1.17 49446 16735 2 960.539239 481.2769 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3361.9 - 578082 - - - -0.0281 - 1.548 0.309 - 210.4 1 2 0 0 9 0 0 0 3.71E+07 3.17E+07 - - - 2.5874 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.16737.16737.2 0.0644 18-Jun K.IFFAGDTIPK.S "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 5 1107.5964 1.87 49448 16737 2 1107.595602 554.8055 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.84 3362.1 - 281796 - - - -0.7629 - 1.262 0.304 - 67 1 2 0 -0.0008 10 0 0 0 7.04E+07 3.77E+07 - - - 1.9356 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.16743.16743.2 0.0038 16-Nov K.LLC[160.03]GLLAER[166.11].L sp|P14174|MIF_HUMAN 1 1053.588 0.9 49452 16743 2 1053.587746 527.8013 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3362.8 - 1.18E+07 - - - -0.261 - 2.17 0.274 - 411.6 1 2 0 -0.0003 9 0 0 0 7.13E+08 7.92E+08 - - - 3.306 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.16744.16744.2 0.0798 16-Sep R.GLFTGLTPR[166.11].L "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 970.5475 1.16 49453 16744 2 970.547952 486.281 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3363 - 2.28E+06 - - - 0.4286 - 1.884 0.307 - 221.5 1 2 0 0.0004 9 0 0 0 3.65E+07 3.15E+07 - - - 3.1408 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.16745.16745.2 0.0232 18-Sep K.APGLGLVLER.V "sp|Q9Y606|TRUA_HUMAN,tr|G8JLB3|G8JLB3_HUMAN,tr|F5H1S9|F5H1S9_HUMAN" 3 1023.6077 2.04 49454 16745 2 1023.608829 512.8111 tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3 6.05 3363 - 2.99E+06 - - - 1.1225 - 1.689 0.317 - 162.5 1 2 0 0.0011 10 0 0 0 2.62E+07 1.29E+07 - - - 2.845 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.16750.16750.2 0.0178 12-Jul R.GFELTFK[136.11].T "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 848.4524 1.38 49459 16750 2 848.454128 425.2335 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3363.6 - 1.45E+06 - - - 2.0897 - 1.489 0.31 - 181 1 2 0 0.0018 7 0 0 0 4.58E+07 3.32E+07 - - - 2.5915 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.16751.16751.2 0.000654 18-Aug R.IFEPILGEGR.A "sp|P28340|DPOD1_HUMAN,tr|M0R3H8|M0R3H8_HUMAN,tr|M0QXQ2|M0QXQ2_HUMAN,tr|M0QXE6|M0QXE6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1129.6132 2.29 49460 16751 2 1129.61739 565.8139 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.53 3363.8 - 1.18E+06 - - - 3.7455 - 1.765 0.373 - 180.3 1 2 0 0.0042 10 0 0 0 9.23E+06 4.03E+06 - - - 3.3805 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.16753.16753.2 0.305 18-Jul K.LSEMSVTLLR.D "sp|Q12756|KIF1A_HUMAN,tr|A0A6Q8PGW8|A0A6Q8PGW8_HUMAN,tr|A0A3B3ITW6|A0A3B3ITW6_HUMAN,tr|A0A3B3ITF7|A0A3B3ITF7_HUMAN,tr|A0A3B3ITE5|A0A3B3ITE5_HUMAN,tr|H7C3Y8|H7C3Y8_HUMAN,tr|A0A3B3IUA1|A0A3B3IUA1_HUMAN,tr|A0A3B3IT28|A0A3B3IT28_HUMAN,tr|A0A6Q8PFR5|A0A6Q8PFR5_HUMAN,tr|A0A3F2YNW9|A0A3F2YNW9_HUMAN,tr|A0A3B3IU40|A0A3B3IU40_HUMAN,tr|A0A6Q8PHQ5|A0A6Q8PHQ5_HUMAN,tr|A0A3B3ITK3|A0A3B3ITK3_HUMAN" 13 1147.6271 1.89 49462 16753 2 1147.62957 574.8208 Kinesin-like protein KIF1A OS=Homo sapiens OX=9606 GN=KIF1A PE=1 SV=2 6 3364 - 524291 - - - 2.1566 - 1.559 0.189 - 76.1 2 2 0 0.0025 10 0 0 0 2.12E+06 1.12E+06 - - - 1.5412 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.16757.16757.2 0.00896 20-Aug K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 0.96 49465 16757 2 1235.75943 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3364.5 - 1.32E+06 - - - -0.5891 - 1.757 0.323 - 197.7 1 2 0 -0.0007 11 0 0 0 4.01E+07 4.17E+07 - - - 2.9511 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.16758.16758.2 0.0106 16-Oct K.LLC[160.03]GLLAER.L sp|P14174|MIF_HUMAN 1 1043.5798 0.9 49466 16758 2 1043.580451 522.7972 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3364.5 - 1.05E+07 - - - 0.6708 - 2.011 0.4 - 292.8 1 2 0 0.0007 9 0 0 0 7.12E+08 7.92E+08 - - - 4.0164 1 230117_WJC_METTL3_WT_vs_EV_F06.16761.16761.2 3.53E-05 18-Nov K.VYVIGSFVDK[136.11].S sp|Q7L0Y3|TM10C_HUMAN 1 1133.6212 0.86 49469 16761 2 1133.623351 567.8179 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3364.9 - 1.68E+06 - - - 1.8878 - 2.168 0.497 - 388.2 1 2 0 0.0021 10 0 0 0 2.20E+07 2.56E+07 - - - 4.8711 0.9915 230117_WJC_METTL3_WT_vs_EV_F06.16762.16762.2 0.149 14-Aug K.LGPLAFYK[136.11].G "sp|Q9UBX3|DIC_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 915.5309 2.2 49470 16762 2 915.535305 458.7727 Mitochondrial dicarboxylate carrier OS=Homo sapiens OX=9606 GN=SLC25A10 PE=1 SV=2 8.59 3365 - 1.34E+06 - - - 4.7677 - 1.387 0.27 - 122.4 1 2 0 0.0044 8 0 0 0 3.59E+07 1.63E+07 - - - 2.0205 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.16763.16763.2 0.000773 18-Oct K.VYVIGSFVDK.S sp|Q7L0Y3|TM10C_HUMAN 1 1125.607 0.86 49471 16763 2 1125.611841 563.8108 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3365.2 - 1.04E+06 - - - 4.291 - 2.338 0.401 - 335.5 1 2 0 0.0048 10 0 0 0 2.20E+07 2.56E+07 - - - 4.3719 1 230117_WJC_METTL3_WT_vs_EV_F06.16768.16768.2 0.000147 22-Oct R.VLIGNVQPGILR.F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1277.782 2.41 49476 16768 2 1277.783447 639.8983 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3365.8 - 177284 - - - 1.1669 - 2.187 0.473 - 313.9 1 2 0 0.0015 12 0 0 0 6.09E+06 2.53E+06 - - - 4.5931 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.16769.16769.2 0.0335 22-Jun R.VLIGNVQPGILR[166.11].F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1287.7902 2.41 49477 16769 2 1287.792354 644.9024 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3366 - 110070 - - - 1.6524 - 1.382 0.255 - 76.2 1 2 0 0.0021 12 0 0 0 6.09E+06 2.53E+06 - - - 1.775 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16771.16771.2 0.318 20-Aug K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.14 49478 16771 2 1245.769154 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3366.3 - 429763 - - - 0.5828 - 1.761 0.367 - 177.4 1 2 0 0.0007 11 0 0 0 1.53E+07 1.34E+07 - - - 3.2823 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.16773.16773.2 0.00509 16-Sep K.FLGELYNYR[166.11].M sp|Q9HAU5|RENT2_HUMAN 1 1183.5901 0.87 49479 16773 2 1183.593366 592.8023 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 6 3366.5 - 304891 - - - 2.7349 - 1.441 0.35 - 239.6 1 2 0 0.0032 9 0 0 0 6.25E+06 7.19E+06 - - - 2.682 0.9672 230117_WJC_METTL3_WT_vs_EV_F06.16776.16776.2 0.596 12-Aug K.LDDLFLK.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 862.48 1.05 49481 16776 2 862.477969 432.2473 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3366.8 - 1.35E+06 - - - -2.378 - 1.574 0.064 - 220.8 1 2 0 -0.0021 7 0 0 0 9.75E+07 9.24E+07 - - - 0.9504 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.16780.16780.2 1.53 12-Sep R.LTLLQLK.G sp|Q8NHP8|PLBL2_HUMAN 1 827.548 1.18 49485 16780 2 827.549562 414.7813 Putative phospholipase B-like 2 OS=Homo sapiens OX=9606 GN=PLBD2 PE=1 SV=2 8.75 3367.3 - 810328 - - - 1.8392 - 1.774 0.172 - 195.6 1 2 0 0.0015 7 0 0 0 1.74E+07 1.48E+07 - - - 2.1272 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.16785.16785.2 0.256 14-Aug R.ILELDQFK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1012.5684 1.08 49487 16785 2 1012.570537 507.2915 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3367.9 - 8.90E+06 - - - 2.0641 - 1.784 0.291 - 154.5 1 2 0 0.0021 8 0 0 0 2.30E+08 2.12E+08 - - - 2.9355 0.9175 230117_WJC_METTL3_WT_vs_EV_F06.16788.16788.2 0.233 14-May K.LEPDILLR[166.11].A "sp|Q01433|AMPD2_HUMAN,tr|A0A7P0TB79|A0A7P0TB79_HUMAN,tr|A0A590UK85|A0A590UK85_HUMAN,tr|A0A5F9UK94|A0A5F9UK94_HUMAN,tr|E9PJF6|E9PJF6_HUMAN,tr|A0A590UJX5|A0A590UJX5_HUMAN,tr|H0Y360|H0Y360_HUMAN,tr|A0A7P0Z4H6|A0A7P0Z4H6_HUMAN,tr|E9PIJ1|E9PIJ1_HUMAN,tr|H0YF16|H0YF16_HUMAN,tr|A0A804CCZ3|A0A804CCZ3_HUMAN" 11 977.5785 2.23 49490 16788 2 977.583339 489.7965 AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2 4.37 3368.2 - 557945 - - - 4.9479 - 1.164 0.176 - 45.1 14 2 0 0.0048 8 0 0 0 1.05E+07 4.71E+06 - - - 0.2854 0.9939 230117_WJC_METTL3_WT_vs_EV_F06.16791.16791.2 0.0834 18-Jul K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 18.95 49493 16791 2 1146.631857 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3368.6 - 281814 - - - 2.9495 - 1.413 0.171 - 94.4 1 2 0 0.0034 10 0 0 0 2.82E+06 1.49E+05 - - - 1.2679 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.16795.16795.2 0.00156 14-Sep R.VWDISGLR[166.11].K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 954.5162 3.19 49495 16795 2 954.517979 478.2654 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3369 - 385071 - - - 1.8261 - 1.878 0.133 - 251.6 1 2 0 0.0017 8 0 0 0 5.76E+07 1.81E+07 - - - 1.9235 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16798.16798.2 0.0224 20-Nov R.ALAAQLPVLPR.S "sp|Q96GK7|FAH2A_HUMAN,tr|C9JGM0|C9JGM0_HUMAN" 2 1147.7077 2.2 49498 16798 2 1147.708425 574.8611 Fumarylacetoacetate hydrolase domain-containing protein 2A OS=Homo sapiens OX=9606 GN=FAHD2A PE=1 SV=1 9.79 3369.3 - 115253 - - - 0.6073 - 2.012 0.341 - 327.1 1 2 0 0.0007 11 0 0 0 3.54E+06 1.61E+06 - - - 3.4507 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.16801.16801.2 0.135 14-Sep R.ILELDQFK.G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1004.5542 1.07 49499 16801 2 1004.558707 503.2844 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3369.7 - 1.41E+07 - - - 4.4398 - 1.881 0.367 - 220.4 1 2 0 0.0045 8 0 0 0 2.27E+08 2.12E+08 - - - 3.6558 0.9969 230117_WJC_METTL3_WT_vs_EV_F06.16802.16802.2 1.16 12-Jul K.LDDLFLK[136.11].R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 870.4942 1.05 49500 16802 2 870.495535 436.2544 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3369.8 - 9.13E+06 - - - 1.5106 - 1.771 0.067 - 143.6 1 2 0 0.0013 7 0 0 0 9.28E+07 8.82E+07 - - - 1.3464 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.16804.16804.2 0.0637 18-Dec R.ALEAELAALR[166.11].Q sp|Q16352|AINX_HUMAN 1 1065.6058 12.91 49502 16804 2 1065.607234 533.8102 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.53 3370 - 1.29E+06 - - - 1.3654 - 1.84 0.251 - 499.2 1 2 0 0.0015 10 0 0 0 1.58E+08 1.23E+07 - - - 2.5965 1 230117_WJC_METTL3_WT_vs_EV_F06.16805.16805.2 8.52E-05 20-Nov R.ALDEGDIALLK[136.11].T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1164.6482 2.38 49503 16805 2 1164.649907 583.3314 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 3370.1 - 658025 - - - 1.5052 - 2.414 0.479 - 261.1 1 2 0 0.0018 11 0 0 0 1.23E+07 5.17E+06 - - - 4.9624 0.9907 230117_WJC_METTL3_WT_vs_EV_F06.16806.16806.2 0.0487 16-Jul K.YFLGQSVLR.S "sp|Q9Y255|PRLD1_HUMAN,tr|D6REW1|D6REW1_HUMAN,tr|D6RC47|D6RC47_HUMAN" 3 1081.592 0.59 49504 16806 2 1081.590081 541.8033 "PRELI domain-containing protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=PRELID1 PE=1 SV=1" 8.75 3370.3 - 601755 - - - -1.802 - 1.317 0.251 - 101 1 2 0 -0.0019 9 0 0 0 9.48E+06 1.59E+07 - - - 1.6909 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16807.16807.2 0.00924 18-Sep R.FVNVVPTFGK.K "sp|P62861|RS30_HUMAN,tr|E9PR30|E9PR30_HUMAN" 2 1106.6124 0.98 49505 16807 2 1106.61476 554.3135 40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1 8.75 3370.4 - 350640 - - - 2.1046 - 1.795 0.385 - 230.9 1 2 0 0.0023 10 0 0 0 1.06E+07 1.09E+07 - - - 3.5168 0.988 230117_WJC_METTL3_WT_vs_EV_F06.16816.16816.2 0.0259 14-Jul R.VWDISGLR.K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 944.508 3.19 49512 16816 2 944.511559 473.2613 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3371.6 - 3.18E+06 - - - 3.8041 - 1.717 0.066 - 235.1 1 2 0 0.0036 8 0 0 0 5.76E+07 1.81E+07 - - - 1.1577 0.9923 230117_WJC_METTL3_WT_vs_EV_F06.16817.16817.2 0.331 14-Aug R.LGISSLIR.E sp|P35573|GDE_HUMAN 1 857.5335 0.8 49513 16817 2 857.534934 429.774 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3371.7 - 4.32E+06 - - - 1.7282 - 1.184 0.153 - 162.3 1 2 0 0.0015 8 0 0 0 3.51E+07 4.39E+07 - - - 0.68 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16819.16819.2 0.00122 16-Aug R.YVANLFPYK[136.11].G "sp|Q15181|IPYR_HUMAN,sp|Q9H2U2|IPYR2_HUMAN,tr|D6RGV9|D6RGV9_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN,tr|D6RGI1|D6RGI1_HUMAN,tr|H0YAK2|H0YAK2_HUMAN" 7 1121.6001 2.42 49515 16819 2 1121.602799 561.8073 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 8.5 3371.9 - 795435 - - - 2.4224 - 1.666 0.405 - 181.5 1 2 0 0.0027 9 0 0 0 5.80E+07 2.40E+07 - - - 3.5082 0.9195 230117_WJC_METTL3_WT_vs_EV_F06.16820.16820.2 0.00556 14-Aug K.VITLC[160.03]LYR.D sp|Q10570|CPSF1_HUMAN 1 1036.5739 0.24 49516 16820 2 1036.579907 519.2942 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.19 3372 - 585966 - - - 5.7594 - 1.506 0.056 - 169.1 1 2 0 0.006 8 0 0 0 1.01E+07 4.27E+07 - - - 0.6876 0.9945 230117_WJC_METTL3_WT_vs_EV_F06.16821.16821.2 0.00119 18-Oct R.FGVITEVDIK[136.11].R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1127.6318 3.55 49517 16821 2 1127.638222 564.8232 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 4.37 3372.2 - 557759 - - - 5.7164 - 2.045 0.301 - 292.5 1 2 0 0.0064 10 0 0 0 2.56E+07 7.19E+06 - - - 3.2591 0.9354 230117_WJC_METTL3_WT_vs_EV_F06.16824.16824.2 0.119 14-Jun K.LEPDILLR.A "sp|Q01433|AMPD2_HUMAN,tr|A0A7P0TB79|A0A7P0TB79_HUMAN,tr|A0A590UK85|A0A590UK85_HUMAN,tr|A0A5F9UK94|A0A5F9UK94_HUMAN,tr|E9PJF6|E9PJF6_HUMAN,tr|A0A590UJX5|A0A590UJX5_HUMAN,tr|H0Y360|H0Y360_HUMAN,tr|A0A7P0Z4H6|A0A7P0Z4H6_HUMAN,tr|E9PIJ1|E9PIJ1_HUMAN,tr|H0YF16|H0YF16_HUMAN,tr|A0A804CCZ3|A0A804CCZ3_HUMAN" 11 967.5702 2.23 49520 16824 2 967.57474 484.7924 AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2 4.37 3372.6 - 304324 - - - 4.6591 - 1.331 0.076 - 108.1 2 2 0 0.0045 8 0 0 0 1.05E+07 4.71E+06 - - - 0.3288 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.16828.16828.2 2.42E-05 18-Aug K.IVAFENAFER.L sp|O60763|USO1_HUMAN 1 1194.6033 0.94 49524 16828 2 1194.604584 598.3089 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 3373.1 - 153154 - - - 1.0556 - 1.829 0.398 - 139.5 1 2 0 0.0013 10 0 0 0 5.72E+06 6.05E+06 - - - 3.6655 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.16829.16829.3 0.0129 18/64 K.MLQAPESVLAEHYQDLR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 2008.9916 0.76 49525 16829 3 2009.005516 670.6711 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3373.2 - 144384 - - - 6.9363 - 2.947 0.462 - 194.5 1 2 0 0.0139 17 0 0 0 1.91E+06 2.53E+06 - - - 6.4174 0.8953 230117_WJC_METTL3_WT_vs_EV_F06.16830.16830.2 10 12-Jul L.C[160.03]GLLAER.L sp|P14174|MIF_HUMAN 1 817.4116 1.01 49526 16830 2 817.412229 409.7131 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3373.3 - 91234.8 - - - 0.7414 - 1.565 0.219 - 151.2 1 1 0 0.0006 7 0 0 0 1.94E+06 1.92E+06 - - - 2.0775 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.16833.16833.2 0.079 12-Jul R.IPTAWFR.E "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN" 2 889.481 -1 49527 16833 2 889.48312 445.7478 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 9.75 3373.7 - 1.22E+06 - - - 2.3576 - 1.321 0.298 - 143.2 1 2 0 0.0021 7 0 0 0 0.00E+00 0.00E+00 - - - 2.1235 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.16834.16834.2 0.0018 18-Aug K.IVAFENAFER[166.11].L sp|O60763|USO1_HUMAN 1 1204.6116 0.93 49528 16834 2 1204.615374 603.3131 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 3373.9 - 342320 - - - 3.1388 - 1.453 0.448 - 125.6 1 2 0 0.0038 10 0 0 0 5.76E+06 6.16E+06 - - - 3.3917 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.16836.16836.2 0.0379 14-Sep K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 0.81 49530 16836 2 988.574898 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3374.1 - 1.32E+06 - - - 4.3821 - 1.819 0.31 - 348.4 1 2 0 0.0043 8 0 0 0 4.30E+09 5.34E+09 - - - 3.1337 0.9933 230117_WJC_METTL3_WT_vs_EV_F06.16840.16840.2 0.000627 20-Sep R.LYPEGLAQLAR.A "sp|P61421|VA0D1_HUMAN,tr|J3QL14|J3QL14_HUMAN,tr|F5GYQ1|F5GYQ1_HUMAN,tr|R4GN72|R4GN72_HUMAN" 4 1229.6768 1.31 49534 16840 2 1229.682715 615.8457 V-type proton ATPase subunit d 1 OS=Homo sapiens OX=9606 GN=ATP6V0D1 PE=1 SV=1 6 3374.6 - 214333 - - - 4.7923 - 1.551 0.278 - 252.4 1 2 0 0.0059 11 0 0 0 1.24E+07 9.46E+06 - - - 2.2798 0.9906 230117_WJC_METTL3_WT_vs_EV_F06.16847.16847.2 0.0596 12-May K.FIDPFC[160.03]K.L sp|Q14684|RRP1B_HUMAN 1 925.4368 3.98 49539 16847 2 925.438772 463.7257 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.83 3375.3 - 711057 - - - 2.1579 - 0.999 0.216 - 69.9 1 2 0 0.002 7 0 0 0 2.68E+07 6.73E+06 - - - 0.6326 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.16849.16849.2 0.0004 16-Aug R.ATLNAFLYR[166.11].T "sp|Q5T2N8|ATD3C_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 3 1077.5847 1.3 49541 16849 2 1077.586255 539.7996 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 8.79 3375.5 - 298827 - - - 1.4894 - 1.949 0.392 - 217.5 1 2 0 0.0016 9 0 0 0 4.51E+07 3.48E+07 - - - 3.8664 0.9919 230117_WJC_METTL3_WT_vs_EV_F06.16855.16855.2 0.639 14-Sep K.LANILFTR[166.11].E sp|Q9HBH5|RDH14_HUMAN 1 956.5683 1.66 49545 16855 2 956.570108 479.2914 Retinol dehydrogenase 14 OS=Homo sapiens OX=9606 GN=RDH14 PE=1 SV=1 9.75 3376.3 - 302153 - - - 1.9194 - 1.545 0.044 - 218.5 1 2 0 0.0018 8 0 0 0 1.22E+07 7.35E+06 - - - 0.6774 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.16856.16856.2 0.16 20-Oct K.LLAAFPGVTPR.V "sp|Q9Y2I1|NISCH_HUMAN,tr|C9J715|C9J715_HUMAN" 2 1140.6655 2.81 49546 16856 2 1140.665287 571.34 Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3 9.75 3376.4 - 387136 - - - -0.2122 - 1.792 0.249 - 270.5 1 2 0 -0.0002 11 0 0 0 8.88E+06 3.16E+06 - - - 2.4581 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.16857.16857.2 0.0278 14-Oct K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 0.81 49547 16857 2 998.583625 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3376.5 - 2.02E+07 - - - 4.7958 - 1.941 0.374 - 430.5 1 2 0 0.0048 8 0 0 0 4.30E+09 5.34E+09 - - - 3.8021 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.16858.16858.2 0.0104 16-Jul K.IDPEAFITR.H sp|Q92616|GCN1_HUMAN 1 1060.5553 1.2 49548 16858 2 1060.559034 531.2849 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3376.6 - 960920 - - - 3.5114 - 1.468 0.284 - 160.6 1 2 0 0.0037 9 0 0 0 2.97E+07 2.47E+07 - - - 2.2481 0.9952 230117_WJC_METTL3_WT_vs_EV_F06.16864.16864.2 2.41 14-Jul R.DILLQGLK[136.11].A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 906.563 0.85 49552 16864 2 906.564108 454.2888 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3377.4 - 1.13E+06 - - - 1.2575 - 1.418 0.123 - 136 1 2 0 0.0011 8 0 0 0 1.75E+07 2.05E+07 - - - 1.0024 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.16867.16867.2 0.0214 18-Jul R.VIAIDIDPVK[136.11].L sp|Q96RS0|TGS1_HUMAN 1 1089.6525 1.95 49555 16867 2 1089.653878 545.8335 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 4.21 3377.7 - 522324 - - - 1.2545 - 1.495 0.286 - 106.7 1 2 0 0.0014 10 0 0 0 2.15E+07 1.10E+07 - - - 2.2754 0.9959 230117_WJC_METTL3_WT_vs_EV_F06.16868.16868.2 0.339 16-Sep K.IDVGDVILK.V sp|Q12923|PTN13_HUMAN 1 970.5699 5.19 49556 16868 2 970.57486 486.2922 Tyrosine-protein phosphatase non-receptor type 13 OS=Homo sapiens OX=9606 GN=PTPN13 PE=1 SV=2 4.21 3377.9 - 384871 - - - 5.1125 - 2.099 0.258 - 136.6 1 2 0 0.005 9 0 0 0 1.31E+07 2.52E+06 - - - 3.0901 0.996 230117_WJC_METTL3_WT_vs_EV_F06.16869.16869.2 0.000671 18-Sep K.C[160.03]LEPTVALLR[166.11].W "sp|Q8TCG1|CIP2A_HUMAN,tr|A0A087X211|A0A087X211_HUMAN" 2 1180.6514 1.91 49557 16869 2 1180.657409 591.333 Protein CIP2A OS=Homo sapiens OX=9606 GN=CIP2A PE=1 SV=2 5.99 3378 - 255219 - - - 5.1319 - 1.784 0.341 - 212.8 1 2 0 0.0061 10 0 0 0 1.40E+07 7.36E+06 - - - 3.1735 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.16870.16870.2 0.011 18-Oct K.IEDMAVSLIR[166.11].E sp|Q15776|ZKSC8_HUMAN 1 1155.6197 1.08 49558 16870 2 1155.6242 578.8171 Zinc finger protein with KRAB and SCAN domains 8 OS=Homo sapiens OX=9606 GN=ZKSCAN8 PE=1 SV=2 4.37 3378.1 - 146760 - - - 3.881 - 1.853 0.357 - 232.3 1 2 0 0.0045 10 0 0 0 3.82E+06 3.53E+06 - - - 3.3981 0.9968 230117_WJC_METTL3_WT_vs_EV_F06.16879.16879.2 0.664 14-Aug K.LPLDVLGR[166.11].V "sp|Q9UBC2|EP15R_HUMAN,tr|M0R2S2|M0R2S2_HUMAN,tr|M0R165|M0R165_HUMAN" 3 891.5417 3.1 49563 16879 2 891.542534 446.7781 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 5.84 3379.3 - 299232 - - - 0.9108 - 1.45 0.162 - 232.4 1 2 0 0.0008 8 0 0 0 5.01E+07 1.62E+07 - - - 1.3579 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.16880.16880.2 0.0117 14-Aug R.LELSVLYK.E "sp|Q96FW1|OTUB1_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 5 963.5641 2.98 49564 16880 2 963.566756 482.7893 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 6 3379.4 - 153923 - - - 2.773 - 1.845 0.252 - 171.8 1 2 0 0.0027 8 0 0 0 2.54E+07 8.53E+06 - - - 2.7486 0.8635 230117_WJC_METTL3_WT_vs_EV_F06.16881.16881.2 1.58 12-May K.ILPWYPK[136.11].V "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN,tr|H0Y815|H0Y815_HUMAN" 3 923.536 3.62 49565 16881 2 923.53521 462.7753 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 8.59 3379.6 - 452285 - - - -0.8825 - 0.921 0.088 - 64.4 2 2 0 -0.0008 7 0 0 0 6.43E+07 1.78E+07 - - - -0.7045 0.9709 230117_WJC_METTL3_WT_vs_EV_F06.16882.16882.2 0.232 12-Aug R.LLQLWEK[136.11].N "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 936.5524 1.34 49566 16882 2 936.557158 469.2835 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 6 3379.7 - 369072 - - - 5.0771 - 1.385 0.144 - 145.7 1 2 0 0.0048 7 0 0 0 8.73E+07 6.54E+07 - - - 1.1351 0.8503 230117_WJC_METTL3_WT_vs_EV_F06.16886.16886.2 0.219 12-Jun K.IFNFYPR.K "sp|O14531|DPYL4_HUMAN,tr|Q5T0Q6|Q5T0Q6_HUMAN" 2 955.4916 1.66 49568 16886 2 955.487056 478.7531 Dihydropyrimidinase-related protein 4 OS=Homo sapiens OX=9606 GN=DPYSL4 PE=1 SV=2 8.75 3380.2 - 556102 - - - -4.7431 - 1.019 0.234 - 88.6 1 2 0 -0.0045 7 0 0 0 4.49E+06 2.71E+06 - - - 0.8275 1 230117_WJC_METTL3_WT_vs_EV_F06.16889.16889.2 0.000643 20-Dec R.FDLALAATEAR.Q sp|Q6PD62|CTR9_HUMAN 1 1176.6139 2.66 49571 16889 2 1176.616368 589.3142 RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1 4.37 3380.6 - 680973 - - - 2.1077 - 2.7 0.472 - 478.7 1 2 0 0.0025 11 0 0 0 8.31E+06 3.12E+06 - - - 5.2134 0.9889 230117_WJC_METTL3_WT_vs_EV_F06.16891.16891.2 0.864 14-Jun K.YVVGLIIK[136.11].T "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 911.5935 1.48 49573 16891 2 911.593641 456.804 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3380.8 - 431856 - - - 0.1108 - 1.204 0.139 - 84.1 1 2 0 0.0001 8 0 0 0 4.86E+07 3.28E+07 - - - 0.6275 0.9877 230117_WJC_METTL3_WT_vs_EV_F06.16892.16892.2 0.226 22-Aug -.MVPPVQVSPLIK[136.11].L sp|P56385|ATP5I_HUMAN 1 1314.7825 1.47 49574 16892 2 1314.77993 658.3985 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3380.9 - 387188 - - - -1.9395 - 1.516 0.188 - 89.6 1 2 0 -0.0026 12 0 0 0 2.55E+07 1.73E+07 - - - 1.5235 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.16899.16899.2 0.00154 18-Aug R.LLLNNDNLLR.E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1196.6877 1.35 49579 16899 2 1196.689409 599.3511 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3381.9 - 1.76E+06 - - - 1.4106 - 1.919 0.435 - 197.5 1 2 0 0.0017 10 0 0 0 1.45E+08 1.07E+08 - - - 4.0728 0.9811 230117_WJC_METTL3_WT_vs_EV_F06.16901.16901.2 0.814 12-May K.VLLPFTR.A sp|Q8TEM1|PO210_HUMAN 1 844.5171 2.42 49581 16901 2 844.517167 423.2658 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 9.72 3382.1 - 1.45E+06 - - - 0.1101 - 1.155 0.103 - 95 1 2 0 0.0001 7 0 0 0 5.20E+07 2.15E+07 - - - 0.2583 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.16902.16902.2 0.0044 18-Sep R.LLLNNDNLLR[166.11].E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1206.696 1.36 49582 16902 2 1206.695638 604.3553 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3382.3 - 1.27E+06 - - - -0.2925 - 2.12 0.357 - 271.5 1 2 0 -0.0004 10 0 0 0 1.55E+08 1.14E+08 - - - 3.7751 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.16903.16903.2 0.0236 12-Aug K.TDFGIFR.M "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 10 854.4287 2.17 49583 16903 2 854.428991 428.2216 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.5 3382.4 - 1.24E+06 - - - 0.3956 - 1.345 0.322 - 297 1 2 0 0.0003 7 0 0 0 1.85E+07 8.55E+06 - - - 2.3583 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.16905.16905.2 0.0102 14-Jul R.LMGDYLLR.G "sp|O60232|ZNRD2_HUMAN,tr|H0YEK1|H0YEK1_HUMAN,tr|E9PK41|E9PK41_HUMAN,tr|H0YEB6|H0YEB6_HUMAN" 4 979.5161 12.97 49585 16905 2 979.519713 490.7653 Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1 5.84 3382.6 - 793085 - - - 3.7008 - 1.497 0.397 - 117.3 1 2 0 0.0036 8 0 0 0 3.46E+07 2.66E+06 - - - 3.1889 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.16906.16906.2 0.0202 12-Jul K.TDFGIFR[166.11].M "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 10 864.4369 2.36 49586 16906 2 864.437205 433.2257 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.5 3382.8 - 645258 - - - 0.3262 - 1.527 0.204 - 150.7 1 2 0 0.0003 7 0 0 0 1.85E+07 7.83E+06 - - - 1.8889 0.9416 230117_WJC_METTL3_WT_vs_EV_F06.16912.16912.2 0.647 22-Aug -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 1.47 49590 16912 2 1306.765393 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3383.5 - 1.70E+06 - - - -2.2093 - 1.338 0.115 - 96.8 3 2 0 -0.0029 12 0 0 0 2.55E+07 1.73E+07 - - - 0.4425 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.16913.16913.2 0.837 12-Aug R.IQLFLAR[166.11].L "sp|Q96FV9|THOC1_HUMAN,tr|A0A087WWS1|A0A087WWS1_HUMAN,tr|A0A087WY84|A0A087WY84_HUMAN,tr|J3KT14|J3KT14_HUMAN" 4 869.5362 0.45 49591 16913 2 869.535904 435.7754 THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1 9.75 3383.6 - 1.12E+06 - - - -0.3899 - 1.912 0.116 - 191.3 1 2 0 -0.0003 7 0 0 0 9.33E+06 2.06E+07 - - - 1.9514 1 230117_WJC_METTL3_WT_vs_EV_F06.16918.16918.2 0.00011 18-Nov K.AVFVPDIYSR.T sp|O94874|UFL1_HUMAN 1 1165.6132 1.9 49594 16918 2 1165.611969 583.8139 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.88 3384.3 - 547180 - - - -1.0209 - 2.14 0.473 - 454.6 1 2 0 -0.0012 10 0 0 0 1.43E+07 7.51E+06 - - - 4.6578 1 230117_WJC_METTL3_WT_vs_EV_F06.16920.16920.2 3.71E-06 24-Oct R.ILGVGPDDPDLVR.A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1364.73 1.96 49596 16920 2 1364.731449 683.3723 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3384.6 - 0 - - - 1.0764 - 2.196 0.562 - 336.1 1 2 0 0.0015 13 0 0 0 5.83E+06 2.97E+06 - - - 5.2104 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.16923.16923.2 0.00714 18-Aug K.C[160.03]LEPTVALLR.W "sp|Q8TCG1|CIP2A_HUMAN,tr|A0A087X211|A0A087X211_HUMAN" 2 1170.6431 2.03 49597 16923 2 1170.642432 586.3288 Protein CIP2A OS=Homo sapiens OX=9606 GN=CIP2A PE=1 SV=2 5.99 3385 - 543451 - - - -0.5535 - 1.381 0.393 - 119.4 1 2 0 -0.0006 10 0 0 0 1.67E+07 8.22E+06 - - - 2.8445 0.9913 230117_WJC_METTL3_WT_vs_EV_F06.16924.16924.2 0.000638 18-Sep K.AVFVPDIYSR[166.11].T sp|O94874|UFL1_HUMAN 1 1175.6214 1.91 49598 16924 2 1175.616155 588.818 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.88 3385.1 - 354377 - - - -4.4861 - 1.909 0.393 - 298.9 1 2 0 -0.0053 10 0 0 0 1.44E+07 7.51E+06 - - - 3.7468 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.16930.16930.2 0.0421 14-Jul K.YVVGLIIK.T "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 903.5793 1.48 49601 16930 2 903.579961 452.7969 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3385.9 - 5.68E+06 - - - 0.6873 - 1.389 0.349 - 139.5 1 2 0 0.0006 8 0 0 0 4.86E+07 3.28E+07 - - - 2.6095 0.998 230117_WJC_METTL3_WT_vs_EV_F06.16931.16931.2 0.068 16-Aug K.LFSELPLAK.K "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1016.5906 1.24 49602 16931 2 1016.589938 509.3026 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 6 3385.9 - 4.89E+06 - - - -0.6837 - 1.572 0.293 - 196.6 1 2 0 -0.0007 9 0 0 0 1.29E+08 1.05E+08 - - - 2.5135 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16933.16933.2 0.000205 24-Aug R.ILGVGPDDPDLVR[166.11].A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1374.7383 1.99 49604 16933 2 1374.739736 688.3764 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3386.2 - 409368 - - - 1.0809 - 1.854 0.375 - 223.3 1 2 0 0.0015 13 0 0 0 5.45E+06 2.74E+06 - - - 3.3947 0.999 230117_WJC_METTL3_WT_vs_EV_F06.16938.16938.2 0.0187 14-Sep K.MFAEIMMK[136.11].L "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1007.4734 0.78 49607 16938 2 1007.473949 504.744 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 5.75 3386.8 - 936997 - - - 0.5777 - 1.595 0.276 - 231.6 1 2 0 0.0006 8 0 0 0 1.46E+07 1.86E+07 - - - 2.4874 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.16940.16940.2 0.000416 18-Aug R.LLYEALVDC[160.03]K[136.11].K "sp|Q7L2H7|EIF3M_HUMAN,tr|J3KNJ2|J3KNJ2_HUMAN,tr|E9PRY0|E9PRY0_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 4 1230.641 0.73 49609 16940 2 1230.639851 616.3278 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 4.37 3387 - 277411 - - - -0.902 - 1.808 0.454 - 184.6 1 2 0 -0.0011 10 0 0 0 4.44E+06 6.07E+06 - - - 4.047 0.9956 230117_WJC_METTL3_WT_vs_EV_F06.16945.16945.2 0.32 18-Jul R.LGLSTLGELK.Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1029.607 2.67 49612 16945 2 1029.609243 515.8108 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3387.6 - 3.63E+06 - - - 2.1678 - 1.43 0.158 - 86.1 1 2 0 0.0022 10 0 0 0 3.11E+08 1.16E+08 - - - 1.2057 1 230117_WJC_METTL3_WT_vs_EV_F06.16947.16947.2 0.000182 18-Sep K.VFEVMLATDR.S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1179.5958 1.65 49614 16947 2 1179.596822 590.8052 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3387.8 - 483382 - - - 0.8706 - 2.032 0.49 - 361.6 1 2 0 0.001 10 0 0 0 1.55E+07 9.42E+06 - - - 4.6389 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16948.16948.2 0.00303 18-Oct K.VFEVMLATDR[166.11].S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1189.6041 1.62 49615 16948 2 1189.607492 595.8093 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3387.9 - 297099 - - - 2.8808 - 2.13 0.412 - 402.7 1 2 0 0.0034 10 0 0 0 1.56E+07 9.62E+06 - - - 4.1935 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.16953.16953.2 0.00666 18-Oct R.LGLSTLGELK[136.11].Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1037.6212 2.67 49618 16953 2 1037.623815 519.8179 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3388.5 - 3.40E+06 - - - 2.5096 - 2.125 0.362 - 169.8 1 2 0 0.0026 10 0 0 0 3.11E+08 1.16E+08 - - - 3.8179 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.16959.16959.2 0.00114 14-Sep K.AGPIWDLR.L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 926.4974 0.96 49622 16959 2 926.499381 464.256 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3389.3 - 1.80E+06 - - - 2.1371 - 1.423 0.417 - 313.6 1 2 0 0.002 8 0 0 0 3.24E+08 3.36E+08 - - - 3.1843 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.16961.16961.2 0.0316 14-Aug K.AGPIWDLR[166.11].L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 936.5057 0.96 49624 16961 2 936.507282 469.2601 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3389.4 - 2.34E+06 - - - 1.7202 - 1.516 0.384 - 298.7 1 2 0 0.0016 8 0 0 0 3.24E+08 3.36E+08 - - - 3.1316 1 230117_WJC_METTL3_WT_vs_EV_F06.16962.16962.2 6.50E-05 16-Oct R.ELLTEFGYK[136.11].G sp|P49411|EFTU_HUMAN 1 1106.5739 2.34 49625 16962 2 1106.574712 554.2942 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.53 3389.6 - 364034 - - - 0.7094 - 2.003 0.506 - 282.2 1 2 0 0.0008 9 0 0 0 3.62E+07 1.55E+07 - - - 4.7877 1 230117_WJC_METTL3_WT_vs_EV_F06.16964.16964.2 0.000162 18-Nov K.VTDAIVLLDR.E "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1113.6394 2.83 49627 16964 2 1113.640567 557.827 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.21 3389.8 - 237411 - - - 1.0713 - 2.549 0.42 - 381.2 1 2 0 0.0012 10 0 0 0 1.53E+08 5.40E+07 - - - 4.7546 0.996 230117_WJC_METTL3_WT_vs_EV_F06.16971.16971.2 0.0738 12-Jun R.VPFSLLR.G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 830.5014 0.98 49632 16971 2 830.503499 416.258 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3390.7 - 785652 - - - 2.4985 - 1.184 0.247 - 109.8 1 2 0 0.0021 7 0 0 0 5.90E+07 6.03E+07 - - - 1.3999 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.16972.16972.2 0.000186 16-Aug R.ELLTEFGYK.G sp|P49411|EFTU_HUMAN 1 1098.5597 2.48 49633 16972 2 1098.56163 550.2871 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.53 3390.7 - 976100 - - - 1.7323 - 1.581 0.461 - 221.9 1 2 0 0.0019 9 0 0 0 3.61E+07 1.45E+07 - - - 3.7705 0.9944 230117_WJC_METTL3_WT_vs_EV_F06.16973.16973.2 0.0424 12-Jul R.VPFSLLR[166.11].G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 840.5097 1.21 49634 16973 2 840.510886 421.2621 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3390.8 - 778966 - - - 1.4182 - 1.219 0.166 - 215.8 1 2 0 0.0012 7 0 0 0 4.55E+07 3.78E+07 - - - 0.8942 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.16974.16974.2 0.00499 22-Nov K.ALLTPVAIAAGR.K sp|P00390|GSHR_HUMAN 1 1151.7026 3.08 49635 16974 2 1151.704571 576.8586 "Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2" 9.79 3390.8 - 704080 - - - 1.674 - 2.482 0.353 - 429.8 1 2 0 0.0019 12 0 0 0 1.94E+07 6.30E+06 - - - 4.0396 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.16976.16976.2 0.0223 14-Jun K.MFGMVLEK[136.11].L sp|P55060|XPO2_HUMAN 1 961.4856 2.58 49637 16976 2 961.486492 481.7501 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.75 3391 - 363755 - - - 0.8799 - 1.246 0.254 - 63.7 1 2 0 0.0008 8 0 0 0 5.56E+07 2.16E+07 - - - 1.5801 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.16980.16980.2 0.000139 22-Oct K.VLQGDLVMNVYR.D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1405.7388 5.08 49641 16980 2 1405.743217 703.8767 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3391.5 - 0 - - - 3.1627 - 1.891 0.46 - 292.9 1 2 0 0.0044 12 0 0 0 1.39E+06 2.73E+05 - - - 4.1135 0.8521 230117_WJC_METTL3_WT_vs_EV_F06.16983.16983.2 3.11 14-Jun K.MFGMVLEK.L sp|P55060|XPO2_HUMAN 1 953.4714 2.36 49642 16983 2 953.474498 477.743 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.75 3391.9 - 951083 - - - 3.2009 - 0.863 0.071 - 74.8 1 2 0 0.0031 8 0 0 0 4.53E+07 1.92E+07 - - - -0.8799 0.9065 230117_WJC_METTL3_WT_vs_EV_F06.16984.16984.2 0.00605 22-Jun R.IINEPTAAAIAY.G "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 16 1245.6605 - 49643 16984 2 1245.663157 623.8375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4 3392 - 446064 - - - 2.1298 - 1.322 0.338 - 74.7 1 1 0 0.0027 12 0 0 0 - - - - - 2.2711 1 230117_WJC_METTL3_WT_vs_EV_F06.16994.16994.2 4.01E-06 18-Dec K.VTDAIVLLDR[166.11].E "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1123.6476 2.82 49651 16994 2 1123.650523 562.8311 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.21 3393.2 - 1.17E+06 - - - 2.5622 - 2.684 0.469 - 611 1 2 0 0.0029 10 0 0 0 1.53E+08 5.41E+07 - - - 5.26 0.9896 230117_WJC_METTL3_WT_vs_EV_F06.16998.16998.2 0.0938 12-Jul K.SYSLLFR[166.11].V "sp|Q15022|SUZ12_HUMAN,tr|J3QQW9|J3QQW9_HUMAN" 2 894.4839 1.32 49655 16998 2 894.487316 448.2492 Polycomb protein SUZ12 OS=Homo sapiens OX=9606 GN=SUZ12 PE=1 SV=3 8.46 3393.7 - 556207 - - - 3.8491 - 1.385 0.166 - 153.1 1 2 0 0.0034 7 0 0 0 1.09E+07 8.23E+06 - - - 1.298 0.9784 230117_WJC_METTL3_WT_vs_EV_F06.17007.17007.2 0.443 12-Jun R.DGFGFIK.C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 782.3963 1.97 49662 17007 2 782.39693 392.2054 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3394.8 - 1.21E+06 - - - 0.818 - 0.885 0.181 - 132.7 1 2 0 0.0006 7 0 0 0 5.54E+07 2.81E+07 - - - -0.0094 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.17009.17009.2 21.1 16-Oct K.R[166.11]VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1057.7239 1.21 49664 17009 2 1057.725554 529.8692 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3395 - 496781 - - - 1.5883 - 1.794 0.145 - 161.8 1 2 0 0.0017 9 0 0 0 2.17E+08 1.80E+08 - - - 1.8023 0.9948 230117_WJC_METTL3_WT_vs_EV_F06.17010.17010.2 0.0487 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 2.07 49665 17010 2 1235.766219 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3395.1 - 309450 - - - 4.9047 - 1.979 0.238 - 243.7 1 2 0 0.0061 11 0 0 0 1.59E+07 7.68E+06 - - - 2.6435 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17014.17014.2 0.000131 14-Sep K.VDLVLLGK.Q sp|P38117|ETFB_HUMAN 1 855.543 1.73 49667 17014 2 855.544673 428.7788 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3395.7 - 4.44E+06 - - - 2.0093 - 1.977 0.416 - 297.3 1 2 0 0.0017 8 0 0 0 8.14E+07 4.70E+07 - - - 4.1687 0.9826 230117_WJC_METTL3_WT_vs_EV_F06.17021.17021.2 2.08 12-Jun R.DGFGFIK[136.11].C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 790.4105 2.08 49672 17021 2 790.411609 396.2125 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3396.5 - 1.14E+06 - - - 1.4157 - 0.983 0.15 - 128.4 1 2 0 0.0011 7 0 0 0 5.53E+07 2.66E+07 - - - 0.0942 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.17031.17031.2 0.122 16-Oct K.RVLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1037.7073 1.21 49680 17031 2 1037.708247 519.8609 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3397.5 - 7.65E+06 - - - 0.8798 - 1.712 0.293 - 172.4 1 2 0 0.0009 9 0 0 0 2.17E+08 1.80E+08 - - - 2.7603 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17032.17032.2 0.00483 14-Sep K.VDLVLLGK[136.11].Q sp|P38117|ETFB_HUMAN 1 863.5572 2.84 49681 17032 2 863.558072 432.7859 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3397.6 - 3.65E+06 - - - 1.063 - 2.018 0.404 - 312.4 1 2 0 0.0009 8 0 0 0 1.92E+08 6.76E+07 - - - 4.1422 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17033.17033.2 3.65E-05 20-Aug R.IDGLAALSMDR.T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1160.586 1.68 49682 17033 2 1160.586647 581.3003 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3397.7 - 1.35E+06 - - - 0.5937 - 2.028 0.348 - 155.9 1 2 0 0.0007 11 0 0 0 1.53E+07 9.11E+06 - - - 3.5238 0.9756 230117_WJC_METTL3_WT_vs_EV_F06.17039.17039.2 5.11E-05 14-Sep K.PFYPALIR.Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 975.5542 0.8 49686 17039 2 975.556136 488.7844 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.18 3398.4 - 3.48E+06 - - - 1.9968 - 1.915 0.44 - 361.6 1 1 0 0.0019 8 0 0 0 5.34E+07 6.69E+07 - - - 4.2497 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.17040.17040.2 0.00622 18-Sep R.LVLSTFSNIR.E sp|Q8WVV4|POF1B_HUMAN 1 1148.6554 999 49687 17040 2 1148.659581 575.335 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 9.75 3398.6 - 964175 - - - 3.6756 - 1.78 0.447 - 201.9 1 2 0 0.0042 10 0 0 0 9.90E+06 0.00E+00 - - - 3.9507 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.17044.17044.2 5.07E-05 22-Oct R.AAVLFATDIAAR.G "sp|Q13206|DDX10_HUMAN,tr|A0A3B3ISR7|A0A3B3ISR7_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 3 1217.6768 0.89 49691 17044 2 1217.674689 609.8457 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 5.88 3398.9 - 210290 - - - -1.7517 - 2.111 0.342 - 317 1 2 0 -0.0021 12 0 0 0 3.69E+06 4.14E+06 - - - 3.5323 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.17051.17051.2 0.0152 14-Aug K.IMLAIITK.M "sp|P78412|IRX6_HUMAN,sp|P78414|IRX1_HUMAN,sp|P78413|IRX4_HUMAN,sp|Q9BZI1|IRX2_HUMAN,sp|P78411|IRX5_HUMAN,sp|P78415|IRX3_HUMAN,tr|D6RAS8|D6RAS8_HUMAN" 7 901.5671 0.54 49696 17051 2 901.5692 451.7908 Iroquois-class homeodomain protein IRX-6 OS=Homo sapiens OX=9606 GN=IRX6 PE=1 SV=3 8.75 3399.9 - 295492 - - - 2.3725 - 1.522 0.338 - 125.2 1 2 0 0.0021 8 0 0 0 7.58E+06 1.40E+07 - - - 2.8036 0.9959 230117_WJC_METTL3_WT_vs_EV_F06.17055.17055.2 0.00136 22-Dec R.AAVLFATDIAAR[166.11].G "sp|Q13206|DDX10_HUMAN,tr|A0A3B3ISR7|A0A3B3ISR7_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 3 1227.6851 0.84 49700 17055 2 1227.69232 614.8498 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 5.88 3400.3 - 374748 - - - 5.8875 - 2.19 0.39 - 373.4 1 2 0 0.0072 12 0 0 0 3.47E+06 4.14E+06 - - - 3.9818 0.8895 230117_WJC_METTL3_WT_vs_EV_F06.17063.17063.2 0.136 14-Aug K.PFYPALIR[166.11].Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 985.5625 0.8 49705 17063 2 985.564671 493.7885 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.18 3401.2 - 2.27E+06 - - - 2.2454 - 1.44 0.27 - 287.4 1 1 0 0.0022 8 0 0 0 5.22E+07 6.51E+07 - - - 2.1343 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.17064.17064.2 0.0115 14-Aug R.LDNIFLTR.M "sp|Q9BQ52|RNZ2_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|V9GYS7|V9GYS7_HUMAN,tr|J3QLK4|J3QLK4_HUMAN,tr|V9GYU5|V9GYU5_HUMAN,tr|V9GZ72|V9GZ72_HUMAN,tr|J3QL08|J3QL08_HUMAN,tr|J3QRS2|J3QRS2_HUMAN" 8 990.5498 0.18 49706 17064 2 990.548453 496.2822 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 5.84 3401.2 - 1.63E+06 - - - -1.3911 - 1.617 0.371 - 193.2 1 2 0 -0.0014 8 0 0 0 2.87E+07 1.61E+08 - - - 3.2302 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.17067.17067.2 0.0105 18-Aug R.FFNYVPSGIR.C "sp|Q969X6|UTP4_HUMAN,tr|H3BPD7|H3BPD7_HUMAN" 2 1198.6135 1.69 49709 17067 2 1198.616372 600.314 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 8.75 3401.5 - 375268 - - - 2.4011 - 1.315 0.28 - 138.8 1 2 0 0.0029 10 0 0 0 1.74E+07 1.03E+07 - - - 1.8725 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17071.17071.2 0.0111 16-Nov R.FAVGIVIGR.N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 930.5651 1.43 49711 17071 2 930.566648 466.2898 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3401.9 - 1.38E+07 - - - 1.6775 - 1.87 0.428 - 521.3 1 2 0 0.0016 9 0 0 0 1.69E+08 1.18E+08 - - - 4.0126 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17072.17072.2 0.0043 16-Nov R.FAVGIVIGR[166.11].N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 940.5734 1.59 49712 17072 2 940.575017 471.294 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3401.9 - 1.09E+07 - - - 1.7649 - 2.042 0.463 - 484.3 1 2 0 0.0017 9 0 0 0 1.92E+08 1.21E+08 - - - 4.5256 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17073.17073.2 0.0237 18-Dec R.LINLVGESLR[166.11].L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1122.6636 3.87 49713 17073 2 1122.666079 562.3391 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6 3402 - 4.21E+06 - - - 2.1823 - 2.317 0.301 - 504.1 1 2 0 0.0025 10 0 0 0 2.76E+08 7.13E+07 - - - 3.6089 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17076.17076.2 0.0468 14-Sep R.ITVLEALR.H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 913.5597 1.24 49716 17076 2 913.561084 457.7871 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3402.2 - 1.66E+06 - - - 1.5511 - 1.978 0.305 - 291.4 1 2 0 0.0014 8 0 0 0 1.26E+08 1.02E+08 - - - 3.3504 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17079.17079.2 0.00468 20-Nov K.ALADVATVLGR.A "sp|Q92542|NICA_HUMAN,tr|H0Y6T7|H0Y6T7_HUMAN" 2 1084.6241 6.36 49719 17079 2 1084.62471 543.3193 Nicastrin OS=Homo sapiens OX=9606 GN=NCSTN PE=1 SV=2 5.88 3402.6 - 446984 - - - 0.6011 - 1.987 0.316 - 242 1 2 0 0.0007 11 0 0 0 8.46E+06 1.33E+06 - - - 3.2323 0.9752 230117_WJC_METTL3_WT_vs_EV_F06.17087.17087.2 0.922 12-Jul K.FGLYLPK.F sp|O75746|CMC1_HUMAN 1 836.4796 3.77 49725 17087 2 836.481801 419.2471 Calcium-binding mitochondrial carrier protein Aralar1 OS=Homo sapiens OX=9606 GN=SLC25A12 PE=1 SV=2 8.59 3403.5 - 461300 - - - 2.6002 - 1.087 0.108 - 116.5 1 2 0 0.0022 7 0 0 0 6.60E+06 1.75E+06 - - - 0.1023 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17092.17092.2 0.015 14-Aug R.ITVLEALR[166.11].H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 923.5679 1.23 49728 17092 2 923.569009 462.7912 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3404.2 - 4.15E+06 - - - 1.1607 - 1.752 0.34 - 232.9 1 2 0 0.0011 8 0 0 0 1.26E+08 1.02E+08 - - - 3.2431 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.17093.17093.2 0.784 14-Aug R.IAYFTLPK.T sp|Q92900|RENT1_HUMAN 1 951.543 0.74 49729 17093 2 951.545676 476.7788 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.59 3404.2 - 1.45E+06 - - - 2.8606 - 1.533 0.238 - 177.1 1 2 0 0.0027 8 0 0 0 6.49E+07 8.80E+07 - - - 2.0865 0.9595 230117_WJC_METTL3_WT_vs_EV_F06.17095.17095.2 0.00236 16-Sep F.VLVLYDEIK.K "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 3 1090.6274 0.18 49731 17095 2 1090.626925 546.321 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 4.37 3404.5 - 829483 - - - -0.4465 - 1.988 0.444 - 235.6 1 1 0 -0.0005 9 0 0 0 1.60E+07 9.08E+07 - - - 4.3081 0.9888 230117_WJC_METTL3_WT_vs_EV_F06.17096.17096.3 0.00163 14/48 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.47 49732 17096 3 1574.90718 525.975 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3404.6 - 593713 - - - 2.5309 - 2.497 0.381 - 290.8 1 2 1 0.004 13 0 0 0 7.11E+06 4.82E+06 - - - 5.2677 0.9824 230117_WJC_METTL3_WT_vs_EV_F06.17097.17097.2 3.8 14-Jul R.LLLAALGR[166.11].R "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 835.5519 1.32 49733 17097 2 835.552812 418.7832 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 9.75 3404.7 - 465472 - - - 1.0999 - 1.41 0.002 - 146.5 1 2 0 0.0009 8 0 0 0 4.91E+07 3.73E+07 - - - 0.0917 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.17099.17099.2 0.146 14-Sep K.LMNLWTER[166.11].F "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1071.5411 0.35 49735 17099 2 1071.540692 536.7778 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 3405 - 246036 - - - -0.3537 - 1.615 0.312 - 278 1 2 0 -0.0004 8 0 0 0 2.07E+08 5.98E+08 - - - 2.791 0.9122 230117_WJC_METTL3_WT_vs_EV_F06.17109.17109.2 0.767 22-Jun K.LIETFSPTESLR.M sp|A6NGG8|PCARE_HUMAN 1 1391.7296 2.03 49743 17109 2 1391.726149 696.8721 Photoreceptor cilium actin regulator OS=Homo sapiens OX=9606 GN=PCARE PE=1 SV=1 4.53 3406.2 - 291482 - - - -2.5127 - 1.368 0.092 - 41.1 4 2 0 -0.0035 12 0 0 0 1.39E+07 6.85E+06 - - - 0.2749 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.17115.17115.2 0.149 14-Sep K.AGISFIIK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 847.5167 0.88 49747 17115 2 847.517548 424.7656 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.8 3406.9 - 1.94E+06 - - - 0.9534 - 1.588 0.153 - 186.5 1 2 0 0.0008 8 0 0 0 1.85E+09 2.10E+09 - - - 1.5656 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.17118.17118.2 0.00542 18-Nov R.LLDYVPIGPR.F "sp|P46459|NSF_HUMAN,tr|K7EQD6|K7EQD6_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 4 1141.6495 1.73 49750 17118 2 1141.65314 571.832 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.84 3407.2 - 586069 - - - 3.149 - 2.14 0.361 - 336.3 1 2 0 0.0036 10 0 0 0 4.05E+07 2.34E+07 - - - 3.8299 0.9493 230117_WJC_METTL3_WT_vs_EV_F06.17121.17121.2 1.46 22-Jul K.LIETFSPTESLR[166.11].M sp|A6NGG8|PCARE_HUMAN 1 1401.7379 2.07 49753 17121 2 1401.735323 701.8762 Photoreceptor cilium actin regulator OS=Homo sapiens OX=9606 GN=PCARE PE=1 SV=1 4.53 3407.6 - 425847 - - - -1.8498 - 1.419 0.076 - 45.6 2 2 0 -0.0026 12 0 0 0 1.39E+07 6.72E+06 - - - 0.3878 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.17124.17124.2 0.000161 14-Nov K.LMNLWTER.F "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1061.5328 0.35 49754 17124 2 1061.5355 531.7737 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 3408 - 4.36E+06 - - - 2.5425 - 1.974 0.447 - 507.9 1 2 0 0.0027 8 0 0 0 2.07E+08 5.98E+08 - - - 4.3927 0.9857 230117_WJC_METTL3_WT_vs_EV_F06.17126.17126.2 0.327 16-Aug R.GLVGEIIK[136.11]R[166.11].F "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1001.6352 1.89 49756 17126 2 1001.636653 501.8249 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3408.1 - 1.69E+07 - - - 1.4157 - 1.523 0.014 - 184 2 2 0 0.0014 9 0 0 0 2.23E+08 1.18E+08 - - - 0.2265 0.956 230117_WJC_METTL3_WT_vs_EV_F06.17127.17127.2 0.00531 16-Sep F.ADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 952.5957 9.18 49757 17127 2 952.597416 477.3051 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3408.2 - 3.76E+06 - - - 1.7825 - 1.542 0.378 - 196.9 1 1 0 0.0017 9 0 0 0 3.75E+07 4.08E+06 - - - 3.0853 0.9922 230117_WJC_METTL3_WT_vs_EV_F06.17129.17129.2 0.0282 18-Oct R.LLDYVPIGPR[166.11].F "sp|P46459|NSF_HUMAN,tr|K7EQD6|K7EQD6_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 4 1151.6578 1.73 49759 17129 2 1151.665438 576.8362 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.84 3408.5 - 1.27E+06 - - - 6.6192 - 2.076 0.349 - 307.8 1 2 0 0.0076 10 0 0 0 4.04E+07 2.33E+07 - - - 3.6552 0.9937 230117_WJC_METTL3_WT_vs_EV_F06.17131.17131.2 0.273 12-Jun K.GLLDDLR[166.11].N sp|Q07065|CKAP4_HUMAN 1 810.4475 1.45 49761 17131 2 810.449638 406.231 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.21 3408.7 - 658245 - - - 2.6529 - 1.199 0.201 - 134.1 1 2 0 0.0022 7 0 0 0 4.11E+07 2.84E+07 - - - 1.1 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.17132.17132.2 0.132 20-Sep K.NILAAASPYIR.T "sp|Q9H2C0|GAN_HUMAN,tr|A0A3B3ITY2|A0A3B3ITY2_HUMAN,tr|A0A0S2Z5G5|A0A0S2Z5G5_HUMAN" 3 1187.6663 1.72 49762 17132 2 1187.666908 594.8404 Gigaxonin OS=Homo sapiens OX=9606 GN=GAN PE=1 SV=1 8.75 3408.8 - 593021 - - - 0.5473 - 1.82 0.236 - 206.9 1 2 0 0.0007 11 0 0 0 2.87E+06 1.67E+06 - - - 2.4039 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.17138.17138.2 1.62 14-Jul R.EILETLIK.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 957.5746 1.66 49766 17138 2 957.57635 479.7946 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3409.6 - 3.43E+06 - - - 1.7764 - 1.481 0.188 - 163.9 1 2 0 0.0017 8 0 0 0 1.82E+08 1.10E+08 - - - 1.6135 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.17140.17140.2 0.273 14-Jun K.AVPSWFVR.V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 960.5181 1.88 49768 17140 2 960.52051 481.2663 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3409.7 - 4.18E+06 - - - 2.4705 - 1.233 0.241 - 103.8 1 2 0 0.0024 8 0 0 0 8.66E+07 4.62E+07 - - - 1.452 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.17141.17141.2 0.0222 12-Jul K.ISFELMR.E "sp|Q9UNE7|CHIP_HUMAN,tr|H3BUD0|H3BUD0_HUMAN,tr|H3BTA3|H3BTA3_HUMAN" 3 894.4633 4.99 49769 17141 2 894.465043 448.2389 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 6 3409.8 - 1.20E+06 - - - 1.9218 - 1.472 0.278 - 124.7 1 2 0 0.0017 7 0 0 0 2.42E+07 4.86E+06 - - - 2.3188 0.9716 230117_WJC_METTL3_WT_vs_EV_F06.17142.17142.2 1.65 12-Jul K.GLLDDLR.N sp|Q07065|CKAP4_HUMAN 1 800.4392 1.44 49770 17142 2 800.441123 401.2269 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.21 3410 - 597833 - - - 2.3799 - 1.171 0.054 - 206.7 1 2 0 0.0019 7 0 0 0 4.10E+07 2.84E+07 - - - -0.0606 0.9901 230117_WJC_METTL3_WT_vs_EV_F06.17146.17146.2 0.895 14-Jul R.EILETLIK[136.11].G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 965.5888 1.66 49773 17146 2 965.591475 483.8017 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3410.4 - 1.94E+06 - - - 2.7196 - 1.481 0.077 - 178.3 1 2 0 0.0026 8 0 0 0 1.82E+08 1.10E+08 - - - 0.7933 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17148.17148.2 0.000417 18-Nov R.LGGIGQFLAK.A sp|Q08211|DHX9_HUMAN 1 1002.5862 0.85 49774 17148 2 1002.588061 502.3004 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3410.6 - 2.12E+06 - - - 1.8402 - 2.157 0.278 - 286.7 1 2 0 0.0018 10 0 0 0 3.46E+08 4.07E+08 - - - 3.2395 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.17149.17149.2 0.0204 14-Jul K.AVPSWFVR[166.11].V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 970.5264 2.64 49775 17149 2 970.527983 486.2705 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3410.7 - 2.09E+06 - - - 1.6239 - 1.494 0.196 - 218.7 1 2 0 0.0016 8 0 0 0 1.32E+08 5.01E+07 - - - 1.6989 0.9008 230117_WJC_METTL3_WT_vs_EV_F06.17150.17150.2 3.76 12-May K.EGIILFK[136.11].E sp|P05455|LA_HUMAN 1 826.5044 1.07 49776 17150 2 826.505682 414.2595 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 6.1 3410.7 - 1.58E+06 - - - 1.562 - 0.968 0.021 - 56.8 2 2 0 0.0013 7 0 0 0 9.82E+07 9.14E+07 - - - -1.0418 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17152.17152.2 0.000852 16-Aug R.AGFVPVYLR[166.11].Q "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1030.5839 0.69 49778 17152 2 1030.586099 516.2992 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 8.79 3410.9 - 1.22E+06 - - - 2.1124 - 1.411 0.436 - 204.3 1 2 0 0.0022 9 0 0 0 4.54E+07 6.61E+07 - - - 3.2567 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.17153.17153.2 0.09 16-Jun R.VLIFSQMTR[166.11].V "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 1103.6037 0.95 49779 17153 2 1103.604774 552.8091 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 9.72 3411 - 713277 - - - 0.9995 - 1.445 0.23 - 69.8 1 2 0 0.0011 9 0 0 0 1.93E+07 2.04E+07 - - - 1.8044 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17154.17154.2 0.245 16-Sep R.VLIFSQMTR.V "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 1093.5954 0.95 49780 17154 2 1093.597716 547.805 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 9.72 3411.1 - 699097 - - - 2.1169 - 1.96 0.291 - 230.2 1 2 0 0.0023 9 0 0 0 1.93E+07 2.04E+07 - - - 3.1365 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17155.17155.2 0.000739 18-Dec K.VALDLDPYVK.K sp|O95295|SNAPN_HUMAN 1 1131.6176 2.2 49781 17155 2 1131.620176 566.8161 SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN PE=1 SV=1 4.21 3411.2 - 326540 - - - 2.2976 - 2.227 0.429 - 431.9 1 2 0 0.0026 10 0 0 0 2.81E+07 1.28E+07 - - - 4.4437 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.17159.17159.2 0.03 14-Sep K.TLVLLMGK[136.11].E "sp|P07737|PROF1_HUMAN,tr|K7EJ44|K7EJ44_HUMAN" 2 881.55 0.89 49783 17159 2 881.55024 441.7823 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 8.41 3411.7 - 3.44E+06 - - - 0.3165 - 1.428 0.298 - 294.6 1 2 0 0.0003 8 0 0 0 4.50E+07 5.03E+07 - - - 2.3164 0.9612 230117_WJC_METTL3_WT_vs_EV_F06.17160.17160.2 0.314 16-Jul K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 145.61 49784 17160 2 1014.539052 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3411.8 - 2.67E+06 - - - 4.4129 - 1.625 0.055 - 101.2 4 2 0 0.0045 9 0 0 0 3.16E+08 2.17E+06 - - - 0.5815 0.9555 230117_WJC_METTL3_WT_vs_EV_F06.17161.17161.2 3.9 14-Jun K.FIIPNVVK[136.11].Y "sp|P00338|LDHA_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 3 936.5888 0.94 49785 17161 2 936.590045 469.3017 L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2 8.75 3411.9 - 2.43E+06 - - - 1.341 - 1.204 0.038 - 71.9 8 2 0 0.0013 8 0 0 0 5.14E+07 5.48E+07 - - - -0.5222 0.998 230117_WJC_METTL3_WT_vs_EV_F06.17162.17162.2 0.0825 14-Sep K.TLVLLMGK.E "sp|P07737|PROF1_HUMAN,tr|K7EJ44|K7EJ44_HUMAN" 2 873.5358 0.89 49786 17162 2 873.535614 437.7752 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 8.41 3412 - 2.42E+06 - - - -0.1683 - 1.464 0.267 - 293.6 1 2 0 -0.0001 8 0 0 0 4.49E+07 5.03E+07 - - - 2.1626 0.9898 230117_WJC_METTL3_WT_vs_EV_F06.17163.17163.2 0.294 14-Aug R.IASFLQLK.N "sp|P42694|HELZ_HUMAN,tr|J3KT20|J3KT20_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 4 918.5539 0.49 49787 17163 2 918.558337 460.2842 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.75 3412.1 - 2.12E+06 - - - 4.8805 - 1.69 0.176 - 108.7 1 2 0 0.0045 8 0 0 0 3.00E+07 6.19E+07 - - - 1.9221 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17164.17164.2 0.00597 16-Nov K.LNNLVLFDK[136.11].A sp|P62851|RS25_HUMAN 1 1082.6215 1.06 49788 17164 2 1082.622016 542.318 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3412.3 - 1.22E+06 - - - 0.4341 - 2.443 0.353 - 388.4 1 2 0 0.0005 9 0 0 0 8.54E+08 8.09E+08 - - - 4.2323 0.9962 230117_WJC_METTL3_WT_vs_EV_F06.17165.17165.2 0.237 14-May R.VIPLPQWK.A sp|Q96ES7|SGF29_HUMAN 1 979.5855 1.58 49789 17165 2 979.58705 490.8 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 8.72 3412.4 - 1.10E+06 - - - 1.5946 - 1.095 0.256 - 74.1 1 2 0 0.0016 8 0 0 0 2.17E+07 1.38E+07 - - - 1.205 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.17170.17170.2 0.0253 26-Sep R.LGGIPVGVVAVETR.T "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 1365.798 2.55 49792 17170 2 1365.802539 683.9063 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 6 3413 - 205453 - - - 3.3233 - 1.842 0.414 - 201.8 1 2 0 0.0045 14 0 0 0 4.50E+06 1.76E+06 - - - 3.6303 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.17173.17173.2 0.238 18-Jul R.IFLPPPPGIR.K "sp|Q8IX18|DHX40_HUMAN,tr|F5H625|F5H625_HUMAN" 2 1105.6648 1.97 49795 17173 2 1105.66601 553.8397 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 9.75 3413.3 - 563910 - - - 1.0935 - 1.461 0.207 - 122.5 1 2 0 0.0012 10 0 0 0 1.33E+07 6.78E+06 - - - 1.6278 0.9818 230117_WJC_METTL3_WT_vs_EV_F06.17178.17178.2 2.31 14-Jun K.FIIPNVVK.Y "sp|P00338|LDHA_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 3 928.5746 0.87 49798 17178 2 928.575976 465.2946 L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2 8.75 3413.9 - 1.73E+06 - - - 1.4937 - 0.927 0.17 - 93.9 1 2 0 0.0014 8 0 0 0 5.19E+07 5.99E+07 - - - 0.0676 1 230117_WJC_METTL3_WT_vs_EV_F06.17181.17181.2 1.04E-06 20-Nov R.IENVVLVVPVK.T "sp|Q9NQW7|XPP1_HUMAN,tr|Q5T6H7|Q5T6H7_HUMAN" 2 1207.754 3.47 49801 17181 2 1207.753703 604.8843 Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3 6 3414.3 - 451018 - - - -0.2542 - 2.255 0.548 - 254.3 1 2 0 -0.0003 11 0 0 0 4.80E+06 1.38E+06 - - - 5.2882 0.9904 230117_WJC_METTL3_WT_vs_EV_F06.17184.17184.2 0.0525 26-Sep R.LGGIPVGVVAVETR[166.11].T "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 1375.8063 2.55 49804 17184 2 1375.807147 688.9104 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 6 3414.7 - 266098 - - - 0.6374 - 1.503 0.07 - 210.7 1 2 0 0.0009 14 0 0 0 4.50E+06 1.76E+06 - - - 0.5803 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17193.17193.2 0.00407 16-Oct K.LNNLVLFDK.A sp|P62851|RS25_HUMAN 1 1074.6073 1.06 49809 17193 2 1074.608285 538.3109 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3415.9 - 2.66E+07 - - - 0.8738 - 2.303 0.341 - 305.3 1 2 0 0.0009 9 0 0 0 8.54E+08 8.09E+08 - - - 3.9728 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.17195.17195.2 0.0676 22-Oct -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 1.68 49811 17195 2 1306.766979 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3416.1 - 399072 - - - -0.9956 - 1.559 0.291 - 192 1 2 0 -0.0013 12 0 0 0 1.29E+07 7.70E+06 - - - 2.3583 0.9936 230117_WJC_METTL3_WT_vs_EV_F06.17196.17196.2 0.00377 16-Aug R.FGIWTGEYK[136.11].C sp|Q9NUD5|ZCHC3_HUMAN 1 1107.548 1.8 49812 17196 2 1107.552519 554.7813 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 6 3416.2 - 370800 - - - 4.0387 - 1.546 0.207 - 104.5 1 2 0 0.0045 9 0 0 0 1.36E+07 7.54E+06 - - - 1.8289 0.9682 230117_WJC_METTL3_WT_vs_EV_F06.17203.17203.2 6.3 12-Aug K.LPLISLR.L "sp|Q96RL7|VP13A_HUMAN,sp|Q6UXB3|LYPD2_HUMAN,sp|Q6DN12|MCTP2_HUMAN,tr|I6L8E2|I6L8E2_HUMAN" 4 810.5327 1.51 49817 17203 2 810.532946 406.2736 Vacuolar protein sorting-associated protein 13A OS=Homo sapiens OX=9606 GN=VPS13A PE=1 SV=2 9.75 3417.1 - 1.15E+06 - - - 0.2739 - 1.19 0.036 - 150.9 1 2 0 0.0002 7 0 0 0 1.27E+07 8.41E+06 - - - -0.142 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.17204.17204.2 0.000202 14-Aug K.MVGFIIGR.G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 891.5 1.41 49818 17204 2 891.498355 446.7573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3417.2 - 1.07E+06 - - - -1.8946 - 1.545 0.4 - 176.8 1 2 0 -0.0017 8 0 0 0 4.45E+08 3.16E+08 - - - 3.3069 0.9951 230117_WJC_METTL3_WT_vs_EV_F06.17205.17205.2 0.763 12-Aug K.YLELFQR[166.11].Q "sp|Q9UBQ6|EXTL2_HUMAN,tr|C9JEG3|C9JEG3_HUMAN" 2 977.521 0.98 49819 17205 2 977.519909 489.7678 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 6 3417.3 - 509216 - - - -1.1028 - 1.511 0.205 - 244.8 1 2 0 -0.0011 7 0 0 0 9.10E+06 9.28E+06 - - - 1.8627 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.17206.17206.2 0.00922 14-Sep R.TFLVPEIK.S sp|Q9P1Y5|CAMP3_HUMAN 1 945.5535 0.83 49820 17206 2 945.554904 473.784 Calmodulin-regulated spectrin-associated protein 3 OS=Homo sapiens OX=9606 GN=CAMSAP3 PE=1 SV=2 5.66 3417.4 - 428958 - - - 1.4648 - 1.505 0.334 - 278.9 1 2 0 0.0014 8 0 0 0 1.20E+07 1.45E+07 - - - 2.7404 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.17208.17208.2 0.0195 14-Aug K.LFIGMISK.K "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 907.5201 1.64 49822 17208 2 907.523346 454.7673 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.75 3417.7 - 421186 - - - 3.5647 - 1.565 0.345 - 151.3 1 2 0 0.0032 8 0 0 0 7.72E+06 4.71E+06 - - - 2.939 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17212.17212.2 0.00114 14-Aug K.LFDFVNAK.K "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 952.5018 0.53 49824 17212 2 952.503507 477.2582 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 5.84 3418.2 - 782079 - - - 1.7732 - 1.621 0.463 - 158.1 1 2 0 0.0017 8 0 0 0 5.11E+07 9.58E+07 - - - 3.917 0.9364 230117_WJC_METTL3_WT_vs_EV_F06.17217.17217.2 2.33 14-Jun R.VIPLPQWK[136.11].A sp|Q96ES7|SGF29_HUMAN 1 987.5997 1.68 49829 17217 2 987.602678 494.8071 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 8.72 3418.7 - 208335 - - - 3.0275 - 0.986 0.086 - 91.2 1 2 0 0.003 8 0 0 0 1.38E+07 8.17E+06 - - - -0.3673 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.17221.17221.2 0.00114 20-Oct R.LYPVLQQSLVR[166.11].A sp|Q5RKV6|EXOS6_HUMAN 1 1324.7742 0.89 49831 17221 2 1324.778287 663.3944 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.75 3419.2 - 1.46E+06 - - - 3.0534 - 1.778 0.385 - 270.3 1 2 0 0.004 11 0 0 0 2.43E+07 2.75E+07 - - - 3.4402 0.9323 230117_WJC_METTL3_WT_vs_EV_F06.17222.17222.2 0.001 22-Jun R.VINEPTAAALAY.G "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1231.6449 - 49832 17222 2 1231.646373 616.8297 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4 3419.4 - 993940 - - - 1.2341 - 1.343 0.361 - 67.4 1 1 0 0.0015 12 0 0 0 - - - - - 2.4828 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17227.17227.2 0.00114 22-Jul R.IVPGQFLAVDPK.G sp|Q15393|SF3B3_HUMAN 1 1282.7285 1.35 49837 17227 2 1282.731814 642.3715 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3420 - 551614 - - - 2.5648 - 1.664 0.424 - 108.6 1 2 0 0.0033 12 0 0 0 2.33E+07 1.73E+07 - - - 3.5115 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.17229.17229.2 0.00182 22-Sep R.ILYIVASDPYSR.L "sp|Q9ULT8|HECD1_HUMAN,tr|H0YJD4|H0YJD4_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN,tr|H0YJP0|H0YJP0_HUMAN" 4 1395.7398 5.07 49839 17229 2 1395.738433 698.8772 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 5.83 3420.3 - 406280 - - - -0.9916 - 1.977 0.497 - 301.1 1 2 0 -0.0014 12 0 0 0 3.22E+06 6.35E+05 - - - 4.5048 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.17231.17231.2 0.000554 24-Nov K.LLPHQLYGVVPQA.- "sp|P18887|XRCC1_HUMAN,tr|F5H8D7|F5H8D7_HUMAN" 2 1433.8031 - 49841 17231 2 1433.802349 717.9088 DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2 6.74 3420.6 - 313286 - - - -0.5133 - 1.943 0.43 - 262.9 1 2 0 -0.0007 13 0 0 0 - - - - - 3.9215 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17234.17234.2 0.0152 16-Aug R.TFTNVYWMK[136.11].V sp|Q9HBH1|DEFM_HUMAN 1 1196.578 1.02 49844 17234 2 1196.580201 599.2963 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 8.26 3420.9 - 181862 - - - 1.8678 - 1.558 0.374 - 182 1 2 0 0.0022 9 0 0 0 5.92E+06 5.81E+06 - - - 3.0855 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.17236.17236.2 1.03 18-Jul R.LINLVGESLR.L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1112.6554 3.88 49845 17236 2 1112.656314 557.335 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6 3421.2 - 1.75E+06 - - - 0.8583 - 1.575 0.219 - 98.3 1 2 0 0.001 10 0 0 0 2.77E+08 7.13E+07 - - - 1.9262 1 230117_WJC_METTL3_WT_vs_EV_F06.17240.17240.2 6.89E-07 22-Sep R.IVPGQFLAVDPK[136.11].G sp|Q15393|SF3B3_HUMAN 1 1290.7427 1.35 49848 17240 2 1290.747234 646.3786 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3421.7 - 547288 - - - 3.4941 - 2.153 0.552 - 149.4 1 2 0 0.0045 12 0 0 0 2.33E+07 1.73E+07 - - - 5.1344 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.17242.17242.2 0.014 18-Sep -.MLIEDVDALK.S "sp|Q9P2N5|RBM27_HUMAN,tr|U3KPZ7|U3KPZ7_HUMAN" 2 1145.6002 0.62 49850 17242 2 1145.603605 573.8074 RNA-binding protein 27 OS=Homo sapiens OX=9606 GN=RBM27 PE=1 SV=2 4.03 3422 - 369019 - - - 2.9626 - 1.794 0.341 - 223.7 1 2 0 0.0034 10 0 0 0 1.25E+07 2.03E+07 - - - 3.1899 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.17244.17244.2 0.000325 24-Sep K.LLLGAGAVAYGVR.E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1258.7398 1.35 49852 17244 2 1258.743937 630.3772 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3422.2 - 268708 - - - 3.3208 - 1.944 0.395 - 208.6 1 2 0 0.0042 13 0 0 0 9.92E+07 7.33E+07 - - - 3.6633 1 230117_WJC_METTL3_WT_vs_EV_F06.17245.17245.2 6.37E-05 14/24 K.LLLGAGAVAYGVR[166.11].E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1268.748 1.35 49853 17245 2 1268.75403 635.3813 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3422.4 - 266558 - - - 4.7314 - 2.654 0.512 - 682.5 1 2 0 0.006 13 0 0 0 9.92E+07 7.33E+07 - - - 5.3259 0.9839 230117_WJC_METTL3_WT_vs_EV_F06.17251.17251.2 0.836 12-Jun R.DFYFSVK[136.11].L sp|Q9NY12|GAR1_HUMAN 1 912.4473 0.66 49858 17251 2 912.44757 457.2309 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3422.9 - 1.65E+06 - - - 0.3288 - 1.138 0.115 - 154.7 1 2 0 0.0003 7 0 0 0 5.52E+07 8.30E+07 - - - 0.2999 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.17255.17255.2 1.06E-05 14-Oct R.IVEVLLMK.D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 943.5776 0.98 49860 17255 2 943.581298 472.7961 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3423.4 - 2.63E+06 - - - 3.8926 - 2.153 0.341 - 277.3 1 2 0 0.0037 8 0 0 0 2.19E+08 2.24E+08 - - - 3.8713 0.9777 230117_WJC_METTL3_WT_vs_EV_F06.17256.17256.2 0.405 20-Jun K.VIVGGVDLLAK[136.11].A "sp|Q9Y496|KIF3A_HUMAN,tr|A0A087X011|A0A087X011_HUMAN,tr|H7C2F6|H7C2F6_HUMAN,tr|J3KPF9|J3KPF9_HUMAN,tr|E9PES4|E9PES4_HUMAN" 5 1090.6841 1.4 49861 17256 2 1090.687546 546.3493 Kinesin-like protein KIF3A OS=Homo sapiens OX=9606 GN=KIF3A PE=1 SV=4 5.81 3423.5 - 657261 - - - 3.1173 - 1.171 0.16 - 50.2 4 2 0 0.0034 11 0 0 0 1.02E+07 7.30E+06 - - - 0.3798 0.996 230117_WJC_METTL3_WT_vs_EV_F06.17258.17258.2 0.432 20-Jul K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.96 49863 17258 2 1245.768397 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3423.8 - 530489 - - - -0.0249 - 1.421 0.2 - 127.7 1 2 0 0 11 0 0 0 2.63E+07 1.34E+07 - - - 1.4687 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.17261.17261.2 0.0846 18-Jul R.LLGPC[160.03]MDIMK.R "sp|P13861|KAP2_HUMAN,tr|H7C330|H7C330_HUMAN" 2 1176.5705 1.14 49866 17261 2 1176.572554 589.2925 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.83 3424.2 - 280672 - - - 1.739 - 1.42 0.265 - 91.1 1 2 0 0.002 10 0 0 0 1.73E+06 1.52E+06 - - - 1.9764 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.17267.17267.2 0.111 14-Oct R.IVEVLLMK[136.11].D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 951.5918 0.98 49870 17267 2 951.593928 476.8032 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3424.9 - 1.03E+07 - - - 2.21 - 2.079 0.237 - 268.6 1 2 0 0.0021 8 0 0 0 2.19E+08 2.24E+08 - - - 2.9982 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.17268.17268.2 0.16 16-Aug R.IELLIDAAR.Q sp|Q8IU81|I2BP1_HUMAN 1 1012.5917 1.75 49871 17268 2 1012.591331 507.3031 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.37 3424.9 - 5.25E+06 - - - -0.3605 - 1.607 0.277 - 153 1 2 0 -0.0004 9 0 0 0 2.13E+07 1.22E+07 - - - 2.4592 1 230117_WJC_METTL3_WT_vs_EV_F06.17269.17269.2 0.0477 18-Dec K.VVDLLAPYAK.G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1087.6277 1.6 49872 17269 2 1087.632647 544.8211 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3425 - 3.00E+06 - - - 4.5052 - 2.32 0.441 - 528.7 1 2 0 0.0049 10 0 0 0 4.17E+08 2.61E+08 - - - 4.6458 0.9187 230117_WJC_METTL3_WT_vs_EV_F06.17275.17275.2 0.00595 16-Oct D.IPIILVGNK[136.11].S "sp|P55040|GEM_HUMAN,sp|Q8IXI2|MIRO1_HUMAN,tr|H7BXZ6|H7BXZ6_HUMAN" 3 973.6416 2.12 49878 17275 2 973.644363 487.8281 GTP-binding protein GEM OS=Homo sapiens OX=9606 GN=GEM PE=1 SV=1 8.75 3425.7 - 619498 - - - 2.8861 - 1.954 0.257 - 231.6 1 1 0 0.0028 9 0 0 0 6.48E+06 3.05E+06 - - - 2.8763 1 230117_WJC_METTL3_WT_vs_EV_F06.17283.17283.2 0.00281 18-Dec K.VVDLLAPYAK[136.11].G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1095.6419 1.61 49884 17283 2 1095.643696 548.8282 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3426.8 - 6.61E+06 - - - 1.5963 - 2.204 0.488 - 517.6 1 2 0 0.0017 10 0 0 0 4.22E+08 2.63E+08 - - - 4.8507 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.17284.17284.2 0.139 14-Sep R.LLNIWQER.S sp|Q9NQG5|RPR1B_HUMAN 1 1070.5873 3.07 49885 17284 2 1070.588978 536.3009 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 6 3426.9 - 3.92E+06 - - - 1.587 - 1.956 0.163 - 280.7 1 2 0 0.0017 8 0 0 0 5.56E+07 1.81E+07 - - - 2.2678 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.17285.17285.2 0.0633 16-Jul R.AFLGQVLVR.R "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1001.6022 0.37 49886 17285 2 1001.604926 501.8084 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 9.79 3426.9 - 3.67E+06 - - - 2.7206 - 1.61 0.35 - 128.2 1 2 0 0.0027 9 0 0 0 7.05E+07 1.90E+08 - - - 3.003 0.9923 230117_WJC_METTL3_WT_vs_EV_F06.17286.17286.2 0.0659 12-Jun R.DFYFSVK.L sp|Q9NY12|GAR1_HUMAN 1 904.4331 0.67 49887 17286 2 904.436639 453.2238 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3427 - 5.08E+06 - - - 3.9461 - 1.003 0.346 - 148.7 1 2 0 0.0036 7 0 0 0 5.52E+07 8.28E+07 - - - 1.6049 0.999 230117_WJC_METTL3_WT_vs_EV_F06.17287.17287.2 0.101 14-Aug R.LLNIWQER[166.11].S sp|Q9NQG5|RPR1B_HUMAN 1 1080.5955 3.07 49888 17287 2 1080.598654 541.3051 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 6 3427.1 - 1.47E+06 - - - 2.8734 - 1.908 0.265 - 233.9 1 2 0 0.0031 8 0 0 0 5.56E+07 1.81E+07 - - - 2.9458 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.17291.17291.2 0.000684 18-Oct K.VVDDEIYYFR[166.11].K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1327.6324 2.05 49892 17291 2 1327.636675 664.8235 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3427.5 - 881838 - - - 3.2291 - 1.656 0.463 - 357.3 1 2 0 0.0043 10 0 0 0 1.86E+07 9.08E+06 - - - 3.8673 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.17294.17294.2 0.00452 16-Aug R.TFTNVYWMK.V sp|Q9HBH1|DEFM_HUMAN 1 1188.5638 1.02 49895 17294 2 1188.56656 595.2892 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 8.26 3427.9 - 219556 - - - 2.3507 - 1.305 0.337 - 148 1 2 0 0.0028 9 0 0 0 5.92E+06 5.81E+06 - - - 2.2993 1 230117_WJC_METTL3_WT_vs_EV_F06.17300.17300.2 0.000141 18-Nov K.VVDDEIYYFR.K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1317.6241 2.05 49899 17300 2 1317.626103 659.8193 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3428.6 - 953216 - - - 1.5065 - 2.106 0.487 - 397.9 1 2 0 0.002 10 0 0 0 1.86E+07 9.08E+06 - - - 4.7163 0.9961 230117_WJC_METTL3_WT_vs_EV_F06.17301.17301.2 0.273 16-Jun R.MLPPPPMWR.R "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 5 1123.5671 0.71 49900 17301 2 1123.569474 562.7908 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 9.5 3428.7 - 369281 - - - 2.1325 - 1.311 0.199 - 106 1 2 0 0.0024 9 0 0 0 2.04E+07 2.89E+07 - - - 1.2935 1 230117_WJC_METTL3_WT_vs_EV_F06.17302.17302.2 0.000126 15/22 R.YVVGVLEAAGVR[166.11].Y sp|Q9H9S5|FKRP_HUMAN 1 1241.7007 0.36 49901 17302 2 1241.703891 621.8576 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 6 3428.8 - 326716 - - - 2.536 - 2.634 0.509 - 705 1 2 0 0.0031 12 0 0 0 4.44E+06 1.22E+07 - - - 5.3478 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17303.17303.2 0.0594 16-Nov R.TPLDLAAFK[136.11].G "sp|O15084|ANR28_HUMAN,tr|B4DIW9|B4DIW9_HUMAN" 2 982.5579 1.88 49902 17303 2 982.557554 492.2862 Serine\threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5 5.5 3428.9 - 323979 - - - -0.3348 - 2.099 0.375 - 398.4 1 2 0 -0.0003 9 0 0 0 1.59E+07 8.43E+06 - - - 3.9557 0.9968 230117_WJC_METTL3_WT_vs_EV_F06.17306.17306.2 0.467 12-Jun R.VLFSLVK.R "sp|Q14999|CUL7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 2 804.5109 0.85 49905 17306 2 804.511837 403.2627 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 8.72 3429.3 - 262183 - - - 1.1324 - 1.439 0.173 - 128.2 2 2 0 0.0009 7 0 0 0 4.99E+06 5.88E+06 - - - 1.3372 1 230117_WJC_METTL3_WT_vs_EV_F06.17308.17308.2 0.00236 14/22 K.VLAGVLDSVDVR[166.11].L "sp|Q8NCH0|CHSTE_HUMAN,tr|H0YN65|H0YN65_HUMAN" 2 1251.7062 2.67 49907 17308 2 1251.703799 626.8604 Carbohydrate sulfotransferase 14 OS=Homo sapiens OX=9606 GN=CHST14 PE=1 SV=2 4.21 3429.6 - 152677 - - - -1.9358 - 2.525 0.427 - 849 1 2 0 -0.0024 12 0 0 0 9.24E+06 3.46E+06 - - - 4.6312 0.9923 230117_WJC_METTL3_WT_vs_EV_F06.17312.17312.2 0.0313 16-Jun R.MLPPPPMWR[166.11].R "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 5 1133.5753 0.88 49909 17312 2 1133.579167 567.795 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 9.5 3430.1 - 602648 - - - 3.369 - 1.148 0.25 - 94.7 1 2 0 0.0038 9 0 0 0 1.76E+07 2.01E+07 - - - 1.2856 0.9964 230117_WJC_METTL3_WT_vs_EV_F06.17315.17315.2 0.000263 18-Oct K.WVGVILDEAK.G "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1128.6179 2.63 49912 17315 2 1128.624115 565.3162 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3430.4 - 266913 - - - 5.4979 - 1.991 0.374 - 191 1 2 0 0.0062 10 0 0 0 1.39E+08 5.29E+07 - - - 3.7236 0.9502 230117_WJC_METTL3_WT_vs_EV_F06.17321.17321.2 1.74 14-Jun K.AITAATLK[136.11].F sp|P11277|SPTB1_HUMAN 1 795.4946 0.65 49916 17321 2 795.495251 398.7546 "Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB PE=1 SV=5" 8.8 3431.2 - 334149 - - - 0.8762 - 1.141 0.036 - 119.7 4 2 0 0.0007 8 0 0 0 6.00E+06 9.24E+06 - - - -0.5644 0.9929 230117_WJC_METTL3_WT_vs_EV_F06.17322.17322.2 0.48 14-Jun K.AITAATLK.F sp|P11277|SPTB1_HUMAN 1 787.4804 0.64 49917 17322 2 787.481491 394.7475 "Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB PE=1 SV=5" 8.8 3431.3 - 372066 - - - 1.4438 - 1.266 0.13 - 107.8 1 2 0 0.0011 8 0 0 0 5.92E+06 9.20E+06 - - - 0.7122 0.8647 230117_WJC_METTL3_WT_vs_EV_F06.17323.17323.2 0.568 12-Sep N.IC[160.03]LDILK[136.11].E "sp|O00762|UBE2C_HUMAN,sp|P61086|UBE2K_HUMAN,sp|P61088|UBE2N_HUMAN,sp|Q96LR5|UB2E2_HUMAN,sp|P51965|UB2E1_HUMAN,sp|Q969T4|UB2E3_HUMAN,sp|Q92785|REQU_HUMAN,tr|F8VSD4|F8VSD4_HUMAN,tr|B7Z306|B7Z306_HUMAN,tr|R4GND1|R4GND1_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN,tr|H7C061|H7C061_HUMAN,tr|F8VQQ8|F8VQQ8_HUMAN,tr|F8VV71|F8VV71_HUMAN,tr|A0A1B0GX65|A0A1B0GX65_HUMAN,tr|A0A087X283|A0A087X283_HUMAN,tr|H0YEI1|H0YEI1_HUMAN,tr|C9J2P0|C9J2P0_HUMAN" 18 881.5136 1.57 49918 17323 2 881.515192 441.7641 Ubiquitin-conjugating enzyme E2 C OS=Homo sapiens OX=9606 GN=UBE2C PE=1 SV=1 5.83 3431.4 - 542352 - - - 1.8343 - 1.685 0.148 - 206.7 1 1 0 0.0016 7 0 0 0 1.00E+07 6.38E+06 - - - 1.7869 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.17324.17324.2 0.164 20-Jul K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.15 49919 17324 2 1235.765368 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3431.6 - 316657 - - - 4.216 - 1.663 0.357 - 167.2 1 2 0 0.0052 11 0 0 0 7.50E+06 6.54E+06 - - - 3.0521 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.17330.17330.2 0.22 12-Aug K.TYDLLFK.L sp|P61026|RAB10_HUMAN 1 898.48 0.4 49923 17330 2 898.480656 450.2473 Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1 5.5 3432.2 - 488215 - - - 0.7079 - 1.511 0.259 - 246.5 1 2 0 0.0006 7 0 0 0 1.48E+07 3.71E+07 - - - 2.2617 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.17337.17337.2 0.0081 16-Sep R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.94 49928 17337 2 989.594633 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3433.1 - 1.43E+06 - - - 3.7046 - 2.033 0.355 - 208.4 1 2 0 0.0037 9 0 0 0 2.98E+09 3.17E+09 - - - 3.7145 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.17341.17341.2 0.00189 14-Aug K.FYFEELGK[136.11].Y sp|Q10471|GALT2_HUMAN 1 1039.5106 1.06 49932 17341 2 1039.512092 520.7626 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3433.6 - 541189 - - - 1.4372 - 1.375 0.36 - 168.7 1 2 0 0.0015 8 0 0 0 3.71E+07 3.51E+07 - - - 2.6599 0.9663 230117_WJC_METTL3_WT_vs_EV_F06.17346.17346.2 2.27 26-Jul K.LGGSAVISLEGKPL.- "sp|P23528|COF1_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PK25|E9PK25_HUMAN" 3 1339.7711 13.23 49937 17346 2 1339.774084 670.8928 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6 3434.3 - 161394 - - - 2.2146 - 1.118 0.062 - 70.2 1 2 0 0.003 14 0 0 0 8.22E+05 6.21E+04 - - - -0.2221 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.17350.17350.2 0.00543 16-Oct R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 0.94 49939 17350 2 997.607471 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3434.7 - 1.02E+07 - - - 2.3095 - 2.217 0.394 - 291.8 1 2 0 0.0023 9 0 0 0 2.98E+09 3.16E+09 - - - 4.2537 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17353.17353.2 0.000438 18-Nov R.FSNLLGTVYR.R "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN,tr|C9J544|C9J544_HUMAN" 3 1168.6241 1 49942 17353 2 1168.627327 585.3193 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 8.75 3435 - 562824 - - - 2.7973 - 1.731 0.431 - 348.7 1 2 0 0.0033 10 0 0 0 9.13E+06 9.16E+06 - - - 3.7549 0.999 230117_WJC_METTL3_WT_vs_EV_F06.17356.17356.2 0.033 18-Nov R.FSNLLGTVYR[166.11].R "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN,tr|C9J544|C9J544_HUMAN" 3 1178.6323 1 49945 17356 2 1178.636048 590.3234 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 8.75 3435.3 - 351236 - - - 3.1562 - 2.063 0.298 - 426.7 1 2 0 0.0037 10 0 0 0 9.13E+06 9.16E+06 - - - 3.2622 1 230117_WJC_METTL3_WT_vs_EV_F06.17358.17358.2 5.00E-05 13/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 5.89 49947 17358 2 1484.908784 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3435.6 - 199931 - - - 0.6054 - 2.371 0.529 - 447 1 2 0 0.0009 15 0 0 0 8.16E+07 1.38E+07 - - - 5.0704 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.17362.17362.2 0.0434 18-Oct K.IYVISLAEPR.L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1159.6601 1.33 49950 17362 2 1159.664435 580.8373 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3436.1 - 194092 - - - 3.7295 - 2.235 0.402 - 369.4 1 2 0 0.0043 10 0 0 0 1.29E+08 9.70E+07 - - - 4.2537 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.17365.17365.2 0.00272 18-Sep R.LLFNDVQTLK[136.11].D "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1197.6849 1.04 49953 17365 2 1197.689321 599.8497 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.84 3436.4 - 500318 - - - 3.713 - 2.041 0.347 - 202.1 1 2 0 0.0044 10 0 0 0 2.05E+07 1.98E+07 - - - 3.594 1 230117_WJC_METTL3_WT_vs_EV_F06.17368.17368.2 4.61E-06 22-Nov R.LNVGGTYFLTTR[166.11].Q "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1350.7171 0.54 49956 17368 2 1350.717733 676.3658 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3436.8 - 207443 - - - 0.4531 - 2.25 0.483 - 344.3 1 2 0 0.0006 12 0 0 0 4.64E+06 8.53E+06 - - - 4.7419 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17373.17373.2 0.00282 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 7797.87 49959 17373 2 1006.569568 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3437.4 - 5.30E+06 - - - -0.3278 - 1.93 0.479 - 249.5 1 2 0 -0.0003 9 0 0 0 1.73E+11 2.21E+07 - - - 4.481 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17374.17374.2 0.00752 16-Aug K.VVLPC[160.03]NLLR[166.11].M "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1092.6353 1.98 49960 17374 2 1092.63559 547.3249 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 8.22 3437.5 - 2.92E+06 - - - 0.2599 - 1.583 0.387 - 270.9 1 2 0 0.0003 9 0 0 0 8.62E+07 4.35E+07 - - - 3.2281 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.17377.17377.2 0.0655 18-Jul K.IYVISLAEPR[166.11].L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1169.6684 1.33 49963 17377 2 1169.670767 585.8415 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3437.9 - 1.08E+06 - - - 2.0407 - 1.702 0.244 - 155.8 3 2 0 0.0024 10 0 0 0 1.29E+08 9.70E+07 - - - 2.1137 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.17379.17379.3 7.82E-05 15/44 R.IIPVLLEHGLER.L "sp|P18858|DNLI1_HUMAN,tr|F5GZ28|F5GZ28_HUMAN,tr|M0R0Q7|M0R0Q7_HUMAN" 3 1387.8187 3.1 49965 17379 3 1387.823969 463.6135 DNA ligase 1 OS=Homo sapiens OX=9606 GN=LIG1 PE=1 SV=1 5.4 3438.2 - 522008 - - - 3.7707 - 2.626 0.469 - 301.7 1 2 0 0.0052 12 0 0 0 2.61E+06 8.44E+05 - - - 6.4436 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17380.17380.2 2.09E-05 22-Oct R.LNVGGTYFLTTR.Q "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1340.7089 0.54 49966 17380 2 1340.711606 671.3617 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3438.3 - 480015 - - - 2.0549 - 2.316 0.393 - 298.2 1 2 0 0.0028 12 0 0 0 4.64E+06 8.53E+06 - - - 4.1526 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.17383.17383.2 1.22E-05 28-Oct R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 4.52 49969 17383 2 1494.914572 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3438.7 - 200499 - - - -1.0589 - 2.008 0.482 - 234.1 1 2 0 -0.0016 15 0 0 0 3.39E+07 7.51E+06 - - - 4.3145 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17385.17385.2 0.11 14-Oct K.IDLTLLNR.L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 956.5655 1.21 49970 17385 2 956.567546 479.29 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.84 3438.9 - 3.10E+06 - - - 2.1588 - 2.12 0.297 - 344.4 1 2 0 0.0021 8 0 0 0 6.16E+07 5.07E+07 - - - 3.5002 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.17387.17387.2 0.0132 18-Sep R.LLFNDVQTLK.D "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1189.6707 1.04 49971 17387 2 1189.671951 595.8426 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.84 3439.1 - 1.04E+06 - - - 1.0734 - 1.994 0.358 - 192.1 1 2 0 0.0013 10 0 0 0 2.05E+07 1.98E+07 - - - 3.6112 0.9913 230117_WJC_METTL3_WT_vs_EV_F06.17402.17402.2 0.338 12-May K.LLLDMYR.S "sp|Q5VTR2|BRE1A_HUMAN,sp|O60308|CE104_HUMAN,tr|A0A6Q8PH38|A0A6Q8PH38_HUMAN,tr|A0A6Q8PHR0|A0A6Q8PHR0_HUMAN,tr|A0A6Q8PGF0|A0A6Q8PGF0_HUMAN,tr|J3QLL3|J3QLL3_HUMAN,tr|A0A6Q8PH69|A0A6Q8PH69_HUMAN,tr|A0A6Q8PHE1|A0A6Q8PHE1_HUMAN,tr|Q5SR27|Q5SR27_HUMAN,tr|A0A6Q8PGB3|A0A6Q8PGB3_HUMAN,tr|A0A6Q8PFR4|A0A6Q8PFR4_HUMAN" 11 922.4946 1.43 49984 17402 2 922.496474 462.2546 E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2 5.84 3440.7 - 412202 - - - 2.0054 - 1.191 0.161 - 61 2 2 0 0.0019 7 0 0 0 7.73E+06 5.41E+06 - - - 0.6489 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17404.17404.2 0.135 14-Nov K.IDLTLLNR[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 966.5738 1.21 49985 17404 2 966.575001 484.2942 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.84 3441.1 - 910259 - - - 1.2932 - 2.282 0.322 - 358 1 2 0 0.0013 8 0 0 0 6.16E+07 5.07E+07 - - - 3.9072 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.17413.17413.2 0.00123 20-Jun R.FLPEFAGTQLK[136.11].L sp|Q9UBZ4|APEX2_HUMAN 1 1257.6849 1.33 49991 17413 2 1257.684634 629.8497 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 6 3442.1 - 4.22E+06 - - - -0.1908 - 1.487 0.376 - 110.4 1 2 0 -0.0002 11 0 0 0 6.09E+07 4.58E+07 - - - 2.8914 0.9894 230117_WJC_METTL3_WT_vs_EV_F06.17415.17415.2 0.967 18-Aug K.FLALEGNPLR[166.11].T sp|Q9H9A6|LRC40_HUMAN 1 1138.6374 3.66 49993 17415 2 1138.640814 570.326 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 6 3442.3 - 2.97E+06 - - - 2.986 - 1.284 0.151 - 202.5 1 2 0 0.0034 10 0 0 0 9.72E+07 2.66E+07 - - - 0.853 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.17416.17416.2 0.000242 18-Oct R.AAGVVLEMIR[166.11].E "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN,tr|M0QXI6|M0QXI6_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 4 1067.6037 1.46 49994 17416 2 1067.605198 534.8091 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6.05 3442.4 - 2.68E+06 - - - 1.4303 - 2.001 0.37 - 410.5 1 2 0 0.0015 10 0 0 0 3.50E+07 2.40E+07 - - - 3.7095 0.917 230117_WJC_METTL3_WT_vs_EV_F06.17428.17428.2 0.147 14-Aug K.FDTPFLPK[136.11].P sp|Q14684|RRP1B_HUMAN 1 971.5208 1.33 50003 17428 2 971.519981 486.7677 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.84 3443.8 - 1.11E+06 - - - -0.8111 - 1.557 0.396 - 142.3 1 1 0 -0.0008 8 0 0 0 1.22E+08 9.18E+07 - - - 3.301 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17431.17431.2 0.00625 18-Sep R.VVLPIEAPIR.M sp|P00403|COX2_HUMAN 1 1105.6859 1.52 50005 17431 2 1105.686025 553.8502 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 5.97 3444.2 - 3.79E+07 - - - 0.0859 - 1.693 0.433 - 302.1 1 2 0 0.0001 10 0 0 0 5.29E+08 3.49E+08 - - - 3.7087 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17432.17432.2 0.0908 14-Oct R.AYILNLVK.Q sp|P50991|TCPD_HUMAN 1 932.5695 7.73 50006 17432 2 932.569713 467.292 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.63 3444.2 - 1.23E+07 - - - 0.2241 - 1.75 0.369 - 340 1 2 0 0.0002 8 0 0 0 1.33E+09 1.72E+08 - - - 3.4541 0.9958 230117_WJC_METTL3_WT_vs_EV_F06.17439.17439.2 5.68E-05 20-Dec R.MGPGIGAILER[166.11].S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1122.6095 2.46 50011 17439 2 1122.605444 562.312 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.75 3445 - 2.21E+06 - - - -3.5988 - 1.82 0.47 - 425 1 2 0 -0.004 11 0 0 0 1.82E+08 7.43E+07 - - - 4.1311 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.17440.17440.2 0.0582 14-Sep R.GIFEPFGK.L "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 893.4647 0.7 50012 17440 2 893.465849 447.7396 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 6 3445.1 - 1.10E+06 - - - 1.2815 - 1.509 0.314 - 260.8 1 2 0 0.0011 8 0 0 0 1.13E+08 1.61E+08 - - - 2.6008 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.17457.17457.2 0.218 18-Oct K.IYVISLAEPR.L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1159.6601 1.33 50020 17457 2 1159.658824 580.8373 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3447.4 - 777296 - - - -1.1089 - 2.249 0.413 - 437.2 1 2 0 -0.0013 10 0 0 0 1.29E+08 9.70E+07 - - - 4.3533 1 230117_WJC_METTL3_WT_vs_EV_F06.17460.17460.2 6.10E-05 14/20 R.MGPGIGAILER.S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1112.6012 2.46 50022 17460 2 1112.598623 557.3079 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.75 3447.6 - 7.22E+06 - - - -2.3288 - 2.359 0.543 - 679.6 1 2 0 -0.0026 11 0 0 0 1.82E+08 7.43E+07 - - - 5.3725 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.17465.17465.2 0.0111 18-Aug R.LGLPGEVFGR[166.11].S sp|O95409|ZIC2_HUMAN 1 1053.5847 2.36 50025 17465 2 1053.584799 527.7996 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 6 3448.3 - 2.16E+06 - - - 0.1414 - 1.458 0.368 - 144.7 1 2 0 0.0001 10 0 0 0 2.55E+08 1.08E+08 - - - 2.8115 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17468.17468.2 0.323 16-Oct K.IAFAITAIK[136.11].G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 954.5994 1.2 50026 17468 2 954.600666 478.307 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3448.7 - 3.39E+06 - - - 1.3744 - 2.231 0.242 - 217.6 1 2 0 0.0013 9 0 0 0 4.27E+09 3.55E+09 - - - 3.1495 0.8459 230117_WJC_METTL3_WT_vs_EV_F06.17469.17469.2 0.063 16-Aug R.PLVALLDGR[166.11].D "sp|P56545|CTBP2_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|E7ESU7|E7ESU7_HUMAN,tr|E7EUB3|E7EUB3_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|E7EPF8|E7EPF8_HUMAN,tr|E9PGB1|E9PGB1_HUMAN" 7 962.5788 1.54 50027 17469 2 962.580299 482.2967 C-terminal-binding protein 2 OS=Homo sapiens OX=9606 GN=CTBP2 PE=1 SV=1 6.27 3448.7 - 2.08E+06 - - - 1.5199 - 1.529 0.181 - 188.2 1 1 0 0.0015 9 0 0 0 6.88E+07 4.48E+07 - - - 1.6058 0.9937 230117_WJC_METTL3_WT_vs_EV_F06.17477.17477.2 0.00137 13/20 R.ALTALGLAVPR.G sp|Q9BVQ7|SPA5L_HUMAN 1 1080.6655 5.89 50031 17477 2 1080.660963 541.34 Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2 9.79 3449.6 - 555118 - - - -4.2252 - 2.538 0.339 - 631.5 1 2 0 -0.0046 11 0 0 0 2.66E+07 4.51E+06 - - - 4.063 1 230117_WJC_METTL3_WT_vs_EV_F06.17478.17478.2 5.55E-07 20-Dec R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 999 50032 17478 2 1201.608295 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3449.8 - 972843 - - - -0.7007 - 2.414 0.566 - 701.9 1 2 0 -0.0008 11 0 0 0 1.59E+07 0.00E+00 - - - 5.6053 0.9969 230117_WJC_METTL3_WT_vs_EV_F06.17491.17491.2 0.00953 18-Aug K.LTYGTMVFVR.S sp|Q15067|ACOX1_HUMAN 1 1185.6216 -1 50038 17491 2 1185.620129 593.8181 Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3 8.75 3451.5 - 2.05E+06 - - - -1.2542 - 1.341 0.344 - 132.5 1 2 0 -0.0015 10 0 0 0 0.00E+00 0.00E+00 - - - 2.4003 0.9768 230117_WJC_METTL3_WT_vs_EV_F06.17494.17494.2 0.0639 16-Sep K.SALLALGLK.C sp|Q12874|SF3A3_HUMAN 1 884.5695 3.34 50039 17494 2 884.564786 443.292 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3451.9 - 773376 - - - -5.3337 - 1.822 0.307 - 235.7 1 2 0 -0.0047 9 0 0 0 2.53E+08 7.56E+07 - - - 3.0427 1 230117_WJC_METTL3_WT_vs_EV_F06.17500.17500.2 0.00644 14/18 N.PEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1087.5662 293.31 50041 17500 2 1087.569627 544.7904 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.43 3452.7 - 1.41E+06 - - - 3.1428 - 2.567 0.421 - 825.4 1 1 0 0.0034 10 0 0 0 1.33E+08 4.54E+05 - - - 4.7809 0.9968 230117_WJC_METTL3_WT_vs_EV_F06.17502.17502.2 0.0216 14-Aug R.FLDDLGLK[136.11].F sp|Q14126|DSG2_HUMAN 1 927.5157 1.76 50042 17502 2 927.513389 464.7651 Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2 4.21 3452.9 - 305971 - - - -2.4744 - 1.559 0.4 - 158.5 1 2 0 -0.0023 8 0 0 0 4.24E+07 2.41E+07 - - - 3.3339 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17510.17510.2 0.0203 16-Oct K.IAFAITAIK.G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 946.5852 1.2 50048 17510 2 946.584851 474.2999 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3453.8 - 1.12E+08 - - - -0.3201 - 2.177 0.341 - 273.7 1 2 0 -0.0003 9 0 0 0 4.27E+09 3.55E+09 - - - 3.8102 0.9962 230117_WJC_METTL3_WT_vs_EV_F06.17511.17511.2 0.0577 12-Jun K.ELEFYLR.K "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 968.4967 0.92 50049 17511 2 968.498805 485.2556 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.53 3453.8 - 8.28E+06 - - - 2.1394 - 1.331 0.185 - 227.6 1 2 0 0.0021 7 0 0 0 2.48E+08 2.69E+08 - - - 1.3127 0.999 230117_WJC_METTL3_WT_vs_EV_F06.17512.17512.2 0.0196 16-Sep K.ALQFLEEVK.V sp|P40227|TCPZ_HUMAN 1 1075.5914 999 50050 17512 2 1075.590747 538.803 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 3453.9 - 3.71E+06 - - - -0.5708 - 1.875 0.317 - 238.4 1 2 0 -0.0006 9 0 0 0 5.25E+07 0.00E+00 - - - 3.2008 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.17513.17513.2 3.14E-05 18-Sep R.FQSLGVAFYR.G "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1186.6135 1.81 50051 17513 2 1186.610598 594.314 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 8.75 3454 - 2.27E+06 - - - -2.4406 - 1.975 0.4 - 210.9 1 2 0 -0.0029 10 0 0 0 4.22E+07 2.33E+07 - - - 3.8942 0.99 230117_WJC_METTL3_WT_vs_EV_F06.17514.17514.2 0.0376 16-Oct K.YPQLLPGIR[166.11].G sp|P23526|SAHH_HUMAN 1 1065.621 1.39 50052 17514 2 1065.617117 533.8178 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 8.75 3454.1 - 1.91E+06 - - - -3.6767 - 1.648 0.315 - 315.3 1 2 0 -0.0039 9 0 0 0 5.65E+07 4.05E+07 - - - 2.8116 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.17524.17524.2 0.0274 16-Sep K.SALLALGLK[136.11].C sp|Q12874|SF3A3_HUMAN 1 892.5837 3.34 50057 17524 2 892.586652 447.2991 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3455.5 - 657551 - - - 3.3028 - 2.047 0.286 - 288.7 1 2 0 0.0029 9 0 0 0 2.53E+08 7.56E+07 - - - 3.225 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.17530.17530.2 0.000168 20-Nov K.FSPAGPILSIR[166.11].L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1166.6687 0.96 50060 17530 2 1166.670177 584.3416 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3456.2 - 4.20E+06 - - - 1.254 - 1.999 0.359 - 475.7 1 2 0 0.0015 11 0 0 0 3.46E+08 3.59E+08 - - - 3.5659 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.17531.17531.2 0.000109 20-Dec K.FSPAGPILSIR.L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1156.6604 0.96 50061 17531 2 1156.662847 579.3375 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3456.4 - 3.55E+06 - - - 2.0775 - 2.144 0.357 - 575.9 1 2 0 0.0024 11 0 0 0 3.46E+08 3.59E+08 - - - 3.7403 1 230117_WJC_METTL3_WT_vs_EV_F06.17536.17536.2 0.000393 20-Nov K.LGNPIVPLNIR.L sp|P78527|PRKDC_HUMAN 1 1204.7292 1.01 50062 17536 2 1204.726051 603.3719 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3457.1 - 262893 - - - -2.6072 - 2.151 0.48 - 410.7 1 2 0 -0.0031 11 0 0 0 1.58E+07 1.57E+07 - - - 4.6573 0.9951 230117_WJC_METTL3_WT_vs_EV_F06.17538.17538.2 0.00818 14-Sep K.IIDFGLAR.R "sp|Q86YV6|MYLK4_HUMAN,sp|Q32MK0|MYLK3_HUMAN,sp|Q9H1R3|MYLK2_HUMAN,sp|P53778|MK12_HUMAN,sp|O15264|MK13_HUMAN,sp|P45983|MK08_HUMAN,sp|Q16539|MK14_HUMAN,sp|P45984|MK09_HUMAN,sp|Q15759|MK11_HUMAN,sp|P53779|MK10_HUMAN,sp|Q15746|MYLK_HUMAN,tr|A0A286YFD7|A0A286YFD7_HUMAN,tr|A0A286YES0|A0A286YES0_HUMAN,tr|A0A286YEQ0|A0A286YEQ0_HUMAN,tr|A0A286YEX7|A0A286YEX7_HUMAN,tr|A0A286YFC0|A0A286YFC0_HUMAN,tr|B5MDL5|B5MDL5_HUMAN,tr|A0A286YES9|A0A286YES9_HUMAN,tr|A0A286YF97|A0A286YF97_HUMAN,tr|D6RCB1|D6RCB1_HUMAN,tr|A0A286YF19|A0A286YF19_HUMAN,tr|A0A286YFN2|A0A286YFN2_HUMAN,tr|D6RJF9|D6RJF9_HUMAN,tr|A0A286YEY0|A0A286YEY0_HUMAN,tr|Q5R3E6|Q5R3E6_HUMAN,tr|A0A286YEV8|A0A286YEV8_HUMAN,tr|B4E0K5|B4E0K5_HUMAN,tr|A0A286YF85|A0A286YF85_HUMAN,tr|A0A286YFI3|A0A286YFI3_HUMAN,tr|F8W9R5|F8W9R5_HUMAN,tr|A0A2R8Y4U5|A0A2R8Y4U5_HUMAN,tr|A0A286YFM6|A0A286YFM6_HUMAN,tr|A0A286YEV3|A0A286YEV3_HUMAN,tr|A0A286YF83|A0A286YF83_HUMAN,tr|A0A286YFJ6|A0A286YFJ6_HUMAN,tr|A0A286YF62|A0A286YF62_HUMAN,tr|A0A286YF02|A0A286YF02_HUMAN,tr|J3KNK1|J3KNK1_HUMAN,tr|A0A286YEQ7|A0A286YEQ7_HUMAN,tr|A0A286YFJ4|A0A286YFJ4_HUMAN,tr|A0A1W2PPZ3|A0A1W2PPZ3_HUMAN,tr|A0A286YEN5|A0A286YEN5_HUMAN,tr|A0A286YFA6|A0A286YFA6_HUMAN,tr|A0A1P0B7D2|A0A1P0B7D2_HUMAN,tr|A0A1W2PRF2|A0A1W2PRF2_HUMAN,tr|D7R525|D7R525_HUMAN,tr|A0A286YF35|A0A286YF35_HUMAN,tr|A0A286YFB6|A0A286YFB6_HUMAN,tr|A0A286YFE2|A0A286YFE2_HUMAN,tr|A0A286YEW9|A0A286YEW9_HUMAN,tr|E7EX54|E7EX54_HUMAN" 51 903.5178 2.8 50063 17538 2 903.520701 452.7662 Myosin light chain kinase family member 4 OS=Homo sapiens OX=9606 GN=MYLK4 PE=1 SV=2 5.84 3457.3 - 1.16E+06 - - - 3.2086 - 1.921 0.077 - 223 1 2 0 0.0029 8 0 0 0 3.41E+07 1.22E+07 - - - 1.5778 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.17544.17544.2 0.00205 14-Sep R.GPIAFWAR[166.11].R "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H909|Q5H909_HUMAN" 2 926.5002 0.93 50066 17544 2 926.499838 464.2574 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 9.75 3458.1 - 643971 - - - -0.3821 - 1.7 0.354 - 332.2 1 2 0 -0.0004 8 0 0 0 1.88E+07 2.03E+07 - - - 3.2559 0.9747 230117_WJC_METTL3_WT_vs_EV_F06.17546.17546.2 0.00024 18-Oct D.TLDNDIMLIK.L "sp|P35030|TRY3_HUMAN,tr|A0A7P0MNE9|A0A7P0MNE9_HUMAN" 2 1174.6268 89.45 50067 17546 2 1174.627539 588.3207 Trypsin-3 OS=Homo sapiens OX=9606 GN=PRSS3 PE=1 SV=2 4.21 3458.3 - 5.62E+06 - - - 0.6623 - 1.693 0.494 - 211.4 1 1 0 0.0008 10 0 0 0 1.08E+08 1.21E+06 - - - 4.1591 0.9341 230117_WJC_METTL3_WT_vs_EV_F06.17547.17547.2 3.78E-05 26-Nov R.GLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1541.7726 - 50068 17547 2 1541.771149 771.8936 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3458.5 - 1.49E+06 - - - -0.9236 - 2.017 0.411 - 107.9 1 1 0 -0.0014 14 0 0 0 - - - - - 3.8369 1 230117_WJC_METTL3_WT_vs_EV_F06.17549.17549.2 2.52E-05 13/20 K.VYGAILVAVER.L sp|Q9Y6J9|TAF6L_HUMAN 1 1188.6867 0.94 50070 17549 2 1188.682506 595.3506 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 5.97 3458.7 - 1.95E+06 - - - -3.4938 - 2.518 0.539 - 550.1 1 2 0 -0.0042 11 0 0 0 1.95E+07 2.07E+07 - - - 5.5189 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.17551.17551.2 0.0061 18-Jul K.LLYPLQEVER[166.11].F "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 1268.7004 0.97 50072 17551 2 1268.703384 635.3575 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.53 3459 - 0 - - - 2.3457 - 1.501 0.346 - 159.3 1 2 0 0.003 10 0 0 0 9.12E+06 9.43E+06 - - - 2.7293 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.17554.17554.2 0.00424 14-Jul R.GLFIIDGK[136.11].G sp|P32119|PRDX2_HUMAN 1 869.5102 2.37 50073 17554 2 869.509022 435.7624 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3459.4 - 841213 - - - -1.3594 - 1.392 0.355 - 160.1 1 2 0 -0.0012 8 0 0 0 2.28E+08 9.62E+07 - - - 2.6602 0.9903 230117_WJC_METTL3_WT_vs_EV_F06.17557.17557.2 0.071 14-Jul R.GLFIIDGK.G sp|P32119|PRDX2_HUMAN 1 861.496 2.37 50075 17557 2 861.4936 431.7553 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3459.7 - 2.93E+06 - - - -2.7905 - 1.37 0.304 - 193.9 1 2 0 -0.0024 8 0 0 0 2.28E+08 9.62E+07 - - - 2.235 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.17558.17558.2 0.000556 20-Aug K.LGNPIVPLNIR[166.11].L sp|P78527|PRKDC_HUMAN 1 1214.7375 1.01 50076 17558 2 1214.735238 608.376 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3459.8 - 2.11E+06 - - - -1.8308 - 1.655 0.447 - 201.9 1 2 0 -0.0022 11 0 0 0 1.58E+07 1.57E+07 - - - 3.7047 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.17559.17559.2 0.000114 20-Oct K.VLADLAIYEPK[136.11].T sp|Q9BYC9|RM20_HUMAN 1 1238.7002 1.26 50077 17559 2 1238.70611 620.3574 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3459.9 - 1.39E+06 - - - 4.7792 - 2.024 0.344 - 195 1 2 0 0.0059 11 0 0 0 1.86E+07 1.48E+07 - - - 3.4873 1 230117_WJC_METTL3_WT_vs_EV_F06.17573.17573.2 2.62E-05 18-Dec K.VGDQILLAIK.G sp|Q6P1L8|RM14_HUMAN 1 1068.6543 1.47 50088 17573 2 1068.653262 535.3344 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3461.7 - 2.64E+06 - - - -0.9676 - 2.315 0.527 - 458.7 1 2 0 -0.001 10 0 0 0 4.99E+07 3.40E+07 - - - 5.2761 1 230117_WJC_METTL3_WT_vs_EV_F06.17574.17574.2 0.000122 18-Dec K.VGDQILLAIK[136.11].G sp|Q6P1L8|RM14_HUMAN 1 1076.6685 1.15 50089 17574 2 1076.667397 539.3415 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3461.9 - 2.30E+06 - - - -1.0207 - 2.46 0.435 - 427.3 1 2 0 -0.0011 10 0 0 0 1.87E+07 1.62E+07 - - - 4.7662 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17577.17577.2 0.000139 14-Sep R.GPIAFWAR.R "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H909|Q5H909_HUMAN" 2 916.4919 0.48 50092 17577 2 916.491725 459.2532 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 9.75 3462.1 - 1.71E+06 - - - -0.215 - 1.741 0.41 - 413.1 1 2 0 -0.0002 8 0 0 0 2.15E+07 4.48E+07 - - - 3.7414 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.17585.17585.2 0.0399 18-Oct K.ALLAEGVILR.R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1053.6546 1.35 50098 17585 2 1053.655003 527.8346 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3463.1 - 3.42E+06 - - - 0.354 - 1.957 0.287 - 275.1 1 2 0 0.0004 10 0 0 0 1.49E+08 1.10E+08 - - - 3.0348 0.9949 230117_WJC_METTL3_WT_vs_EV_F06.17587.17587.2 1.82 14-Jul R.NLLTGLVR.H "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 884.5444 1.11 50100 17587 2 884.544523 443.2795 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 9.75 3463.2 - 6.02E+06 - - - 0.1945 - 1.251 0.198 - 163.3 1 2 0 0.0002 8 0 0 0 8.34E+07 7.48E+07 - - - 1.1788 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.17588.17588.2 0.187 20-Oct K.VLADLAIYEPK.T sp|Q9BYC9|RM20_HUMAN 1 1230.686 1.26 50101 17588 2 1230.68472 616.3503 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3463.3 - 1.54E+06 - - - -1.0319 - 1.704 0.228 - 187.1 1 2 0 -0.0013 11 0 0 0 1.86E+07 1.48E+07 - - - 2.1664 1 230117_WJC_METTL3_WT_vs_EV_F06.17589.17589.2 3.74E-05 20-Nov R.LLYC[160.03]TTGVLLR.R "sp|Q6P158|DHX57_HUMAN,sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 3 1307.7271 0.82 50102 17589 2 1307.728451 654.8708 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 8.22 3463.5 - 1.44E+06 - - - 0.9994 - 2.457 0.45 - 530.9 1 2 0 0.0013 11 0 0 0 7.51E+06 9.17E+06 - - - 4.7961 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17592.17592.2 0.0275 18-Sep R.IAEFAFEYAR.N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1215.5924 1.98 50105 17592 2 1215.594451 608.8035 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3463.9 - 1.26E+06 - - - 1.6675 - 2.121 0.274 - 285 1 2 0 0.002 10 0 0 0 1.51E+07 7.62E+06 - - - 3.1629 0.9625 230117_WJC_METTL3_WT_vs_EV_F06.17593.17593.2 0.997 12-Jul K.SLDIFIK.A sp|Q9H583|HEAT1_HUMAN 1 834.4851 0.69 50106 17593 2 834.487087 418.2498 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.55 3464 - 930534 - - - 2.3751 - 1.079 0.064 - 156.3 1 2 0 0.002 7 0 0 0 1.14E+07 1.65E+07 - - - -0.246 0.9937 230117_WJC_METTL3_WT_vs_EV_F06.17594.17594.2 0.0459 16-Aug R.ITELMQVLK[136.11].D "sp|P28288|ABCD3_HUMAN,tr|A0A3B3ITW3|A0A3B3ITW3_HUMAN" 2 1081.6297 0.52 50107 17594 2 1081.635496 541.8221 ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3 PE=1 SV=1 6 3464.1 - 876765 - - - 5.3882 - 1.669 0.307 - 115.3 1 2 0 0.0058 9 0 0 0 4.53E+06 8.71E+06 - - - 2.7886 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17595.17595.2 0.00337 18-Nov R.IAEFAFEYAR[166.11].N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1225.6007 1.98 50108 17595 2 1225.602588 613.8076 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3464.2 - 703814 - - - 1.5454 - 2.231 0.249 - 468.3 1 2 0 0.0019 10 0 0 0 1.51E+07 7.62E+06 - - - 3.1194 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17598.17598.2 0.0289 16-Aug R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.93 50110 17598 2 989.593331 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3464.5 - 863491 - - - 2.3889 - 1.934 0.317 - 166.9 1 2 0 0.0024 9 0 0 0 1.52E+08 1.63E+08 - - - 3.2898 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.17599.17599.2 2.22 18-Dec K.ALLAEGVILR[166.11].R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1063.6629 1.35 50111 17599 2 1063.66482 532.8387 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3464.6 - 1.33E+06 - - - 1.8051 - 1.952 0.144 - 710 1 2 0 0.0019 10 0 0 0 1.49E+08 1.10E+08 - - - 1.971 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.17600.17600.2 0.0179 14-Sep R.LLNVWQVR.S "sp|Q15061|WDR43_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 2 1026.5974 1.12 50112 17600 2 1026.598694 514.306 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 9.75 3464.6 - 1.26E+06 - - - 1.2118 - 1.869 0.365 - 297.6 1 2 0 0.0012 8 0 0 0 2.95E+07 2.64E+07 - - - 3.6227 0.9923 230117_WJC_METTL3_WT_vs_EV_F06.17601.17601.2 0.224 12-Jun R.IIFDDFR[166.11].E sp|P46977|STT3A_HUMAN 1 934.4788 1.2 50113 17601 2 934.480394 468.2467 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.21 3464.7 - 754111 - - - 1.7186 - 1.026 0.211 - 79.7 1 2 0 0.0016 7 0 0 0 4.58E+07 3.81E+07 - - - 0.6803 0.995 230117_WJC_METTL3_WT_vs_EV_F06.17602.17602.2 0.105 12-Jun R.LFLEFER[166.11].K "sp|O43663|PRC1_HUMAN,sp|Q96I25|SPF45_HUMAN,tr|H0YL53|H0YL53_HUMAN" 3 962.5101 0.17 50114 17602 2 962.51333 482.2623 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 3464.8 - 648353 - - - 3.3683 - 1.431 0.2 - 111.1 1 2 0 0.0032 7 0 0 0 1.11E+07 6.36E+07 - - - 1.6527 1 230117_WJC_METTL3_WT_vs_EV_F06.17604.17604.2 3.1 13/22 K.TPAILYTYSGLR.N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1353.7293 2.12 50116 17604 2 1353.73095 677.8719 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3465 - 356732 - - - 1.2543 - 2.626 0.422 - 669.3 1 2 0 0.0017 12 0 0 0 7.89E+06 3.72E+06 - - - 4.6977 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17605.17605.2 0.00158 14-Jul K.GFGFGLVK[136.11].L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 831.4734 1.1 50117 17605 2 831.47368 416.744 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3465.1 - 355981 - - - 0.3067 - 1.45 0.469 - 151.9 1 2 0 0.0003 8 0 0 0 9.10E+07 8.24E+07 - - - 3.6256 0.9939 230117_WJC_METTL3_WT_vs_EV_F06.17610.17610.2 0.451 14-Aug R.GLFIIDDK.G "sp|Q06830|PRDX1_HUMAN,sp|Q13162|PRDX4_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|H7C3T4|H7C3T4_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 5 919.5015 2.04 50121 17610 2 919.502429 460.758 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.21 3465.7 - 4.73E+06 - - - 1.0277 - 1.81 0.002 - 282.1 1 2 0 0.0009 8 0 0 0 5.05E+08 2.48E+08 - - - 0.8449 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.17613.17613.2 0.0954 14-Jul K.TTQLLFLK[136.11].A sp|O94874|UFL1_HUMAN 1 970.5943 2.39 50124 17613 2 970.595648 486.3044 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 8.41 3466.1 - 479474 - - - 1.4218 - 1.369 0.267 - 120.1 1 2 0 0.0014 8 0 0 0 1.54E+07 6.44E+06 - - - 1.9599 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.17615.17615.2 0.00768 20-Oct R.GILEGELEGIR.G "sp|O75600|KBL_HUMAN,tr|H7BZ75|H7BZ75_HUMAN,tr|F2Z340|F2Z340_HUMAN,tr|C9IZC9|C9IZC9_HUMAN" 4 1184.6401 4.73 50126 17615 2 1184.637326 593.3273 "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial OS=Homo sapiens OX=9606 GN=GCAT PE=1 SV=1" 4.25 3466.3 - 424983 - - - -2.3433 - 2.121 0.349 - 258.5 1 2 0 -0.0028 11 0 0 0 2.87E+06 6.06E+05 - - - 3.6519 1 230117_WJC_METTL3_WT_vs_EV_F06.17617.17617.2 0.247 13/22 K.TPAILYTYSGLR[166.11].N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1363.7375 2.12 50128 17617 2 1363.736658 682.876 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3466.6 - 339883 - - - -0.6336 - 2.971 0.418 - 664.5 1 2 0 -0.0009 12 0 0 0 7.89E+06 3.72E+06 - - - 4.9932 1 230117_WJC_METTL3_WT_vs_EV_F06.17623.17623.2 6.33E-06 14/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 3.49 50133 17623 2 1484.906816 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3467.3 - 420538 - - - -0.7199 - 2.434 0.584 - 540.6 1 2 0 -0.0011 15 0 0 0 6.95E+06 1.99E+06 - - - 5.5411 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17625.17625.2 0.0107 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 1372.05 50134 17625 2 1006.571007 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3467.5 - 5.36E+07 - - - 1.1018 - 1.89 0.477 - 246.3 1 2 0 0.0011 9 0 0 0 6.88E+08 5.02E+05 - - - 4.4054 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.17626.17626.2 0.125 14-Jul K.GFGFGLVK.L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 823.4592 1.1 50135 17626 2 823.459555 412.7369 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3467.6 - 2.97E+06 - - - 0.4007 - 1.244 0.428 - 154.7 1 2 0 0.0003 8 0 0 0 9.10E+07 8.24E+07 - - - 2.8606 0.9964 230117_WJC_METTL3_WT_vs_EV_F06.17631.17631.2 0.395 16-Jun R.LNVLANVIR[166.11].K "sp|Q02218|ODO1_HUMAN,sp|Q9ULD0|OGDHL_HUMAN,tr|E9PFG7|E9PFG7_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|A0A0D9SFS3|A0A0D9SFS3_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 6 1020.6319 0.88 50138 17631 2 1020.633654 511.3232 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 9.75 3468.1 - 367388 - - - 1.6852 - 1.695 0.111 - 120.5 2 2 0 0.0017 9 0 0 0 8.65E+06 9.87E+06 - - - 1.2524 0.9866 230117_WJC_METTL3_WT_vs_EV_F06.17635.17635.2 0.145 16-Aug R.ILLLNEMEK[136.11].L "sp|P35573|GDE_HUMAN,tr|A0A1C7CYW1|A0A1C7CYW1_HUMAN" 2 1109.6246 1.96 50142 17635 2 1109.627835 555.8196 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 4.53 3468.6 - 326210 - - - 2.9316 - 1.593 0.037 - 123.8 1 2 0 0.0033 9 0 0 0 8.46E+06 4.32E+06 - - - 0.6603 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17636.17636.2 0.0448 18-Oct R.LPLLAVC[160.03]DYK.Q "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1190.6369 0.56 50143 17636 2 1190.640433 596.3257 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.83 3468.8 - 304468 - - - 2.9404 - 2.201 0.363 - 348.4 1 2 0 0.0035 10 0 0 0 3.18E+06 5.65E+06 - - - 3.9231 1 230117_WJC_METTL3_WT_vs_EV_F06.17639.17639.2 0.000259 22-Dec K.LPVGTTATLYFR[166.11].D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1347.7426 1.39 50146 17639 2 1347.745359 674.8786 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3469.1 - 176672 - - - 2.0419 - 2.256 0.476 - 496.2 1 2 0 0.0028 12 0 0 0 4.81E+06 3.47E+06 - - - 4.6966 0.9917 230117_WJC_METTL3_WT_vs_EV_F06.17641.17641.2 0.136 20-May K.MPFSVYSTLEK.H "sp|Q9H165|BC11A_HUMAN,sp|Q9C0K0|BC11B_HUMAN,tr|D3YTK1|D3YTK1_HUMAN" 3 1300.6373 -1 50148 17641 2 1300.639542 651.3259 B-cell lymphoma\leukemia 11A OS=Homo sapiens OX=9606 GN=BCL11A PE=1 SV=2 5.75 3469.4 - 67085.6 - - - 1.7045 - 1.111 0.212 - 61.8 4 2 0 0.0022 11 0 0 0 0.00E+00 0.00E+00 - - - 0.6219 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.17645.17645.2 0.000254 16-Sep K.FPTLWSGAR[166.11].S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1043.5428 1.4 50150 17645 2 1043.542069 522.7787 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 9.75 3469.9 - 1.90E+06 - - - -0.6861 - 1.94 0.385 - 311.3 1 2 0 -0.0007 9 0 0 0 7.51E+06 5.37E+06 - - - 3.8016 0.999 230117_WJC_METTL3_WT_vs_EV_F06.17648.17648.2 0.433 14-Oct K.ISALALLK[136.11].M sp|Q92905|CSN5_HUMAN 1 835.5622 1.29 50153 17648 2 835.563527 418.7884 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 8.75 3470.1 - 3.50E+06 - - - 1.5403 - 1.71 0.233 - 218.5 1 2 0 0.0013 8 0 0 0 1.20E+07 9.31E+06 - - - 2.3796 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17652.17652.2 0.000661 18-Sep K.ILETLYTLGK.A "sp|Q5W0V3|FHI2A_HUMAN,tr|Q5W0V4|Q5W0V4_HUMAN" 2 1149.6645 999 50157 17652 2 1149.665998 575.8395 FHF complex subunit HOOK interacting protein 2A OS=Homo sapiens OX=9606 GN=FHIP2A PE=1 SV=1 6 3470.5 - 2.65E+06 - - - 1.2804 - 1.928 0.398 - 165.5 1 2 0 0.0015 10 0 0 0 4.73E+06 0.00E+00 - - - 3.8126 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17656.17656.3 0.00224 Nov-36 K.LLLGTLHLPR[166.11].R "sp|Q9H3P2|NELFA_HUMAN,tr|C9JHL4|C9JHL4_HUMAN,tr|H7C3C2|H7C3C2_HUMAN,tr|H7C2M8|H7C2M8_HUMAN,tr|H7C0W2|H7C0W2_HUMAN,tr|F8WF98|F8WF98_HUMAN,tr|F8W954|F8W954_HUMAN,tr|A0A0C4DFX9|A0A0C4DFX9_HUMAN" 8 1141.7211 0.001 50161 17656 3 1141.721666 381.581 Negative elongation factor A OS=Homo sapiens OX=9606 GN=NELFA PE=1 SV=3 9.76 3471 - 1.55E+06 - - - 0.5098 - 2.062 0.275 - 104.9 1 2 0 0.0006 10 0 0 0 0.00E+00 2.90E+06 - - - 3.7193 0.998 230117_WJC_METTL3_WT_vs_EV_F06.17658.17658.2 0.148 20-Aug K.VLVIGELGVGK[136.11].T sp|Q13637|RAB32_HUMAN 1 1090.6841 -1 50163 17658 2 1090.687277 546.3493 Ras-related protein Rab-32 OS=Homo sapiens OX=9606 GN=RAB32 PE=1 SV=3 5.97 3471.2 - 729692 - - - 2.8707 - 1.27 0.341 - 78.6 1 2 0 0.0031 11 0 0 0 0.00E+00 0.00E+00 - - - 2.2052 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.17659.17659.2 0.0352 20-Nov R.LLEQILVAENR[166.11].D sp|Q6SZW1|SARM1_HUMAN 1 1306.7484 -1 50164 17659 2 1306.748504 654.3815 NAD(+) hydrolase SARM1 OS=Homo sapiens OX=9606 GN=SARM1 PE=1 SV=1 4.53 3471.3 - 702112 - - - 0.0635 - 1.593 0.309 - 169.4 1 2 0 0.0001 11 0 0 0 0.00E+00 0.00E+00 - - - 2.5829 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.17668.17668.2 0.13 12-Jul K.GVIFYLR.D "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 9 866.5014 3.92 50172 17668 2 866.503853 434.258 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 8.75 3472.6 - 2.18E+06 - - - 2.8032 - 1.552 0.16 - 188.4 1 2 0 0.0024 7 0 0 0 2.56E+07 6.52E+06 - - - 1.6147 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.17669.17669.2 0.00035 14-Sep K.LMWIPDTK.G sp|P61962|DCAF7_HUMAN 1 1002.5208 1.74 50173 17669 2 1002.524858 502.2677 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.84 3472.6 - 2.09E+06 - - - 4.0089 - 1.786 0.423 - 350 1 2 0 0.004 8 0 0 0 1.60E+07 9.19E+06 - - - 3.9132 0.9924 230117_WJC_METTL3_WT_vs_EV_F06.17670.17670.2 0.109 14-Jul K.TILSLMTR[166.11].E sp|P53396|ACLY_HUMAN 1 943.54 1.07 50174 17670 2 943.542599 472.7773 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.41 3472.7 - 1.93E+06 - - - 2.746 - 1.487 0.103 - 149.6 1 2 0 0.0026 8 0 0 0 1.51E+07 1.42E+07 - - - 0.9976 0.998 230117_WJC_METTL3_WT_vs_EV_F06.17671.17671.2 0.0014 16-Sep K.FPTLWSGAR.S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1033.5345 0.78 50175 17671 2 1033.53858 517.7745 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 9.75 3472.8 - 1.69E+06 - - - 3.9331 - 1.834 0.293 - 348.5 1 2 0 0.0041 9 0 0 0 1.24E+07 1.59E+07 - - - 2.9585 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.17672.17672.2 0.00271 16-Sep R.ILLLNEMEK.L "sp|P35573|GDE_HUMAN,tr|A0A1C7CYW1|A0A1C7CYW1_HUMAN" 2 1101.6104 1.55 50176 17672 2 1101.614237 551.8125 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 4.53 3473 - 1.09E+06 - - - 3.4994 - 1.816 0.352 - 194.6 1 2 0 0.0039 9 0 0 0 8.46E+06 5.46E+06 - - - 3.3658 1 230117_WJC_METTL3_WT_vs_EV_F06.17674.17674.2 3.87E-06 13/22 K.LPVGTTATLYFR.D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1337.7343 1.39 50178 17674 2 1337.735864 669.8744 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3473.2 - 468730 - - - 1.1415 - 2.443 0.535 - 580.9 1 2 0 0.0015 12 0 0 0 4.81E+06 3.47E+06 - - - 5.3423 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17676.17676.2 0.253 20-Nov K.SEIEYYAMLAK[136.11].T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1324.6464 0.81 50180 17676 2 1324.646381 663.3305 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3473.5 - 358897 - - - -0.0445 - 2.395 0.338 - 438 1 2 0 -0.0001 11 0 0 0 2.47E+06 3.03E+06 - - - 3.9002 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17677.17677.2 0.000231 20-Sep K.SEIEYYAMLAK.T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1316.6322 0.78 50181 17677 2 1316.636399 659.3234 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3473.6 - 313897 - - - 3.1588 - 2.02 0.464 - 266.7 1 2 0 0.0042 11 0 0 0 2.47E+06 3.16E+06 - - - 4.3688 0.999 230117_WJC_METTL3_WT_vs_EV_F06.17678.17678.2 0.0231 18-Sep K.WSEALVLYDR[166.11].V sp|Q9UHB9|SRP68_HUMAN 1 1260.6378 -1 50182 17678 2 1260.642519 631.3262 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.37 3473.7 - 292703 - - - 3.737 - 1.96 0.394 - 283.7 1 2 0 0.0047 10 0 0 0 0.00E+00 0.00E+00 - - - 3.828 0.9907 230117_WJC_METTL3_WT_vs_EV_F06.17682.17682.2 0.052 22-Aug R.LPVPESITGFAR.L "sp|Q8N5K1|CISD2_HUMAN,tr|I3L1N9|I3L1N9_HUMAN,tr|A0A2R8Y540|A0A2R8Y540_HUMAN" 3 1285.703 0.24 50186 17682 2 1285.707616 643.8588 CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1 6 3474.3 - 196122 - - - 3.5615 - 1.47 0.16 - 154.8 1 2 0 0.0046 12 0 0 0 2.41E+06 1.00E+07 - - - 1.235 1 230117_WJC_METTL3_WT_vs_EV_F06.17685.17685.2 7.57E-07 18-Dec K.LGDDIDLIVR[166.11].C sp|O15371|EIF3D_HUMAN 1 1137.6269 1.09 50188 17685 2 1137.629394 569.8207 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3474.5 - 3.10E+06 - - - 2.1844 - 2.684 0.501 - 473.2 1 2 0 0.0025 10 0 0 0 1.43E+08 1.31E+08 - - - 5.4965 0.9931 230117_WJC_METTL3_WT_vs_EV_F06.17686.17686.2 0.401 12-Aug K.FIGELFK[136.11].L "sp|O43432|IF4G3_HUMAN,sp|Q04637|IF4G1_HUMAN,tr|A0A804HJV5|A0A804HJV5_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|A0A0U1RQK7|A0A0U1RQK7_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|A0A0A0MSA7|A0A0A0MSA7_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 11 860.4887 0.15 50189 17686 2 860.491905 431.2516 Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2 6 3474.6 - 2.68E+06 - - - 3.677 - 1.513 0.161 - 174.6 1 2 0 0.0032 7 0 0 0 1.55E+07 1.01E+08 - - - 1.5412 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17687.17687.2 0.0129 16-Nov R.LAVLPYELR.F "sp|Q9ULX3|NOB1_HUMAN,tr|H3BUR4|H3BUR4_HUMAN" 2 1072.6281 1.26 50190 17687 2 1072.630299 537.3213 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 6 3474.7 - 2.56E+06 - - - 2.0678 - 2.218 0.243 - 600.3 1 2 0 0.0022 9 0 0 0 7.37E+07 5.84E+07 - - - 3.1397 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17688.17688.2 0.000208 16-Oct R.LIDFLESGK.T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1020.5492 1.39 50191 17688 2 1020.551266 511.2819 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3474.7 - 2.35E+06 - - - 2.0616 - 1.966 0.427 - 269.7 1 2 0 0.0021 9 0 0 0 6.77E+07 4.86E+07 - - - 4.1499 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.17692.17692.2 0.0463 16-Jul R.AVDVGAFLR[166.11].D "sp|Q96BT3|CENPT_HUMAN,tr|H3BUW2|H3BUW2_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 3 956.5319 1.03 50195 17692 2 956.534268 479.2732 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 5.88 3475 - 1.02E+06 - - - 2.4902 - 1.532 0.219 - 116.8 1 2 0 0.0024 9 0 0 0 1.38E+07 1.33E+07 - - - 1.8919 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17696.17696.2 0.052 20-Sep R.ELLIIGGVAAR.D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1110.6761 1.21 50199 17696 2 1110.678495 556.3453 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3475.5 - 666698 - - - 2.1617 - 2.01 0.312 - 236.4 1 2 0 0.0024 11 0 0 0 1.78E+08 1.47E+08 - - - 3.2333 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.17702.17702.2 0.142 18-Dec K.WELNPEIVAR.H sp|Q9BYD2|RM09_HUMAN 1 1225.6455 1.54 50205 17702 2 1225.646512 613.83 "39S ribosomal protein L9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL9 PE=1 SV=2" 4.53 3476.3 - 328574 - - - 0.8077 - 2.219 0.334 - 510.5 1 2 0 0.001 10 0 0 0 2.01E+06 1.31E+06 - - - 3.7324 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.17707.17707.2 0.00481 16-Sep R.LIDFLESGK[136.11].T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1028.5634 1.38 50209 17707 2 1028.565808 515.289 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3477 - 3.83E+06 - - - 2.3781 - 1.677 0.277 - 188.1 1 2 0 0.0024 9 0 0 0 6.70E+07 4.86E+07 - - - 2.5819 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17708.17708.2 0.375 20-Dec R.ELLIIGGVAAR[166.11].D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1120.6844 1.21 50210 17708 2 1120.687386 561.3495 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3477.1 - 1.71E+06 - - - 2.6966 - 2.516 0.339 - 586.5 1 2 0 0.003 11 0 0 0 1.78E+08 1.47E+08 - - - 4.0399 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.17709.17709.2 0.0202 16-Jul R.AVDVGAFLR.D "sp|Q96BT3|CENPT_HUMAN,tr|H3BUW2|H3BUW2_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 3 946.5236 1 50211 17709 2 946.52565 474.2691 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 5.88 3477.2 - 1.23E+06 - - - 2.1489 - 1.513 0.268 - 147.4 1 2 0 0.002 9 0 0 0 1.38E+07 1.38E+07 - - - 2.2178 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.17710.17710.2 0.0101 14-Aug K.WLTLEVC[160.03]R.E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1075.5485 1.56 50212 17710 2 1075.550648 538.7815 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3477.3 - 2.74E+06 - - - 2.0427 - 1.581 0.338 - 243.7 1 2 0 0.0022 8 0 0 0 5.33E+07 3.42E+07 - - - 2.9183 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.17711.17711.2 0.861 14-Aug K.IYQVLDFR.L "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1052.5655 1.17 50213 17711 2 1052.569176 527.29 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 5.84 3477.4 - 1.06E+06 - - - 3.5105 - 1.799 0.237 - 230.4 1 2 0 0.0037 8 0 0 0 1.09E+07 9.32E+06 - - - 2.5614 0.9789 230117_WJC_METTL3_WT_vs_EV_F06.17716.17716.2 0.457 18-Sep K.SSLALGLELR.A sp|Q8TAP8|PPR35_HUMAN 1 1057.6132 2.27 50218 17716 2 1057.619104 529.8139 Protein phosphatase 1 regulatory subunit 35 OS=Homo sapiens OX=9606 GN=PPP1R35 PE=1 SV=1 5.72 3478.1 - 225995 - - - 5.6211 - 1.586 0.188 - 165.2 1 2 0 0.0059 10 0 0 0 2.24E+06 9.86E+05 - - - 1.7151 0.9919 230117_WJC_METTL3_WT_vs_EV_F06.17721.17721.2 0.0314 14-Jul R.GIFPVLC[160.03]K.D "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 932.5154 1.51 50221 17721 2 932.514022 467.265 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 8.22 3478.6 - 4.01E+06 - - - -1.4348 - 1.244 0.258 - 132.3 1 2 0 -0.0013 8 0 0 0 2.16E+07 1.43E+07 - - - 1.6046 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.17723.17723.2 0.154 12-Jun R.ISPWLLR[166.11].V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 893.5362 0.89 50223 17723 2 893.537559 447.7754 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3478.7 - 3.51E+06 - - - 1.4728 - 1.439 0.241 - 160.8 1 2 0 0.0013 7 0 0 0 9.46E+06 1.06E+07 - - - 1.9738 0.999 230117_WJC_METTL3_WT_vs_EV_F06.17724.17724.2 0.0275 14-Jul R.GIFPVLC[160.03]K[136.11].D "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 940.5296 2.18 50224 17724 2 940.531678 471.2721 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 8.22 3478.8 - 2.21E+06 - - - 2.2519 - 1.629 0.286 - 149.7 1 2 0 0.0021 8 0 0 0 1.79E+07 8.20E+06 - - - 2.6244 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17726.17726.2 0.000122 20-Nov R.YIVQVSPLGIR[166.11].L sp|Q10570|CPSF1_HUMAN 1 1253.7371 1.34 50226 17726 2 1253.73994 627.8758 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3479.1 - 1.66E+06 - - - 2.2429 - 1.74 0.528 - 373.8 1 2 0 0.0028 11 0 0 0 1.82E+07 1.35E+07 - - - 4.4383 1 230117_WJC_METTL3_WT_vs_EV_F06.17727.17727.2 0.0105 20-Dec R.YIVQVSPLGIR.L sp|Q10570|CPSF1_HUMAN 1 1243.7289 1.34 50227 17727 2 1243.731949 622.8717 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3479.2 - 1.55E+06 - - - 2.4853 - 2.425 0.453 - 550.6 1 2 0 0.0031 11 0 0 0 1.82E+07 1.35E+07 - - - 4.7823 0.8855 230117_WJC_METTL3_WT_vs_EV_F06.17730.17730.2 0.0522 24-Apr K.TIFPNGSAAEDGR[166.11].L sp|O15018|PDZD2_HUMAN 1 1343.6345 -1 50230 17730 2 1343.629569 672.8245 PDZ domain-containing protein 2 OS=Homo sapiens OX=9606 GN=PDZD2 PE=1 SV=4 4.37 3479.6 - 1.01E+06 - - - -3.6796 - 1.379 0.202 - 27.3 57 2 0 -0.0049 13 0 0 0 0.00E+00 0.00E+00 - - - 0.5718 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.17735.17735.2 0.186 22-Aug K.VFNIYTDATPLR[166.11].V sp|Q8N8A6|DDX51_HUMAN 1 1418.7433 -1 50235 17735 2 1418.744903 710.3789 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 5.81 3480.2 - 530766 - - - 1.1052 - 1.772 0.286 - 146.6 1 2 0 0.0016 12 0 0 0 0.00E+00 0.00E+00 - - - 2.6582 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.17743.17743.2 0.146 16-Oct R.IQDIVGILR.D "sp|P46087|NOP2_HUMAN,tr|F5H5X6|F5H5X6_HUMAN,tr|F5GYR3|F5GYR3_HUMAN" 3 1025.6233 0.84 50241 17743 2 1025.626536 513.8189 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 5.84 3481.2 - 3.39E+06 - - - 3.1259 - 1.908 0.282 - 316.5 1 2 0 0.0032 9 0 0 0 4.70E+07 5.60E+07 - - - 2.9919 1 230117_WJC_METTL3_WT_vs_EV_F06.17744.17744.2 9.69E-07 22-Sep R.VFIGNLNTALVK[136.11].K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1295.7693 0.67 50242 17744 2 1295.772767 648.8919 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3481.3 - 956962 - - - 2.6965 - 2.168 0.592 - 191.4 1 2 0 0.0035 12 0 0 0 8.74E+07 1.30E+08 - - - 5.4484 1 230117_WJC_METTL3_WT_vs_EV_F06.17746.17746.2 3.33E-05 22-Oct R.VFIGNLNTALVK.K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1287.7551 0.67 50244 17746 2 1287.760782 644.8848 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3481.6 - 721373 - - - 4.4333 - 2.146 0.508 - 234.9 1 2 0 0.0057 12 0 0 0 8.74E+07 1.30E+08 - - - 4.8005 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17747.17747.2 0.00467 16-Aug K.VNIIPIIAK.A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 979.643 1.1 50245 17747 2 979.645131 490.8288 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3481.7 - 640128 - - - 2.1722 - 1.709 0.406 - 214.5 1 2 0 0.0021 9 0 0 0 3.76E+07 3.42E+07 - - - 3.5895 1 230117_WJC_METTL3_WT_vs_EV_F06.17748.17748.2 0.000173 16-Oct K.VNIIPIIAK[136.11].A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 987.6572 1.1 50246 17748 2 987.659627 494.8359 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3481.8 - 607906 - - - 2.4543 - 1.967 0.514 - 375.5 1 2 0 0.0024 9 0 0 0 3.76E+07 3.42E+07 - - - 4.7938 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17750.17750.2 0.000787 16-Sep R.FLVQLDDYR.F "sp|Q9HAD4|WDR41_HUMAN,tr|D6RE66|D6RE66_HUMAN,tr|B4DK73|B4DK73_HUMAN,tr|D6RH33|D6RH33_HUMAN,tr|D6RA22|D6RA22_HUMAN,tr|B4DHS8|B4DHS8_HUMAN,tr|D6R9E7|D6R9E7_HUMAN,tr|H0YAA3|H0YAA3_HUMAN,tr|D6RBY6|D6RBY6_HUMAN,tr|H0YAI6|H0YAI6_HUMAN,tr|D6RB94|D6RB94_HUMAN" 11 1167.5924 1.5 50248 17750 2 1167.593912 584.8035 WD repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=WDR41 PE=1 SV=3 4.21 3482.1 - 441482 - - - 1.2744 - 1.773 0.323 - 390.4 1 2 0 0.0015 9 0 0 0 6.01E+06 4.00E+06 - - - 3.083 1 230117_WJC_METTL3_WT_vs_EV_F06.17752.17752.2 2.89E-05 20-Nov R.IVLLDSSLEYK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1278.7071 10.97 50250 17752 2 1278.711736 640.3608 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3482.3 - 393893 - - - 3.6107 - 2.4 0.49 - 381.9 1 2 0 0.0046 11 0 0 0 1.87E+09 1.70E+08 - - - 5.027 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.17756.17756.2 0.0083 16-Jul R.FLVQLDDYR[166.11].F "sp|Q9HAD4|WDR41_HUMAN,tr|D6RE66|D6RE66_HUMAN,tr|B4DK73|B4DK73_HUMAN,tr|D6RH33|D6RH33_HUMAN,tr|D6RA22|D6RA22_HUMAN,tr|B4DHS8|B4DHS8_HUMAN,tr|D6R9E7|D6R9E7_HUMAN,tr|H0YAA3|H0YAA3_HUMAN,tr|D6RBY6|D6RBY6_HUMAN,tr|H0YAI6|H0YAI6_HUMAN,tr|D6RB94|D6RB94_HUMAN" 11 1177.6007 1.53 50254 17756 2 1177.606609 589.8076 WD repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=WDR41 PE=1 SV=3 4.21 3482.8 - 286421 - - - 5.0229 - 1.672 0.449 - 222.8 1 2 0 0.0059 9 0 0 0 6.11E+06 4.00E+06 - - - 3.8425 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17758.17758.2 5.18E-05 30-Sep R.VINEPTAAALAYGLDK.S "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1644.8723 999 50256 17758 2 1644.876802 823.4434 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3483.1 - 200807 - - - 2.7449 - 2.045 0.424 - 160.8 1 2 0 0.0045 16 0 0 0 3.26E+06 0.00E+00 - - - 3.9301 1 230117_WJC_METTL3_WT_vs_EV_F06.17762.17762.2 3.28E-05 13/20 K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 12 50258 17762 2 1204.683672 603.3481 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3483.6 - 5.21E+06 - - - 1.7424 - 2.576 0.475 - 642.3 1 2 0 0.0021 11 0 0 0 1.45E+09 1.20E+08 - - - 5.1085 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.17763.17763.2 0.0571 12-Jul R.YLNFFTK.A sp|P12004|PCNA_HUMAN 1 931.4804 1.43 50259 17763 2 931.482089 466.7475 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3483.7 - 2.94E+06 - - - 1.8626 - 1.375 0.344 - 121.9 1 2 0 0.0017 7 0 0 0 6.36E+07 4.44E+07 - - - 2.5903 0.9935 230117_WJC_METTL3_WT_vs_EV_F06.17764.17764.2 0.463 12-Jun R.YLNFFTK[136.11].A sp|P12004|PCNA_HUMAN 1 939.4946 1.59 50260 17764 2 939.496942 470.7546 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3483.8 - 2.79E+06 - - - 2.5418 - 1.179 0.199 - 102.1 1 2 0 0.0024 7 0 0 0 7.12E+07 4.47E+07 - - - 1.0318 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17765.17765.2 0.0339 14-Oct K.WLTLEVC[160.03]R[166.11].E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1085.5567 1.56 50261 17765 2 1085.559537 543.7856 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3483.9 - 2.29E+06 - - - 2.5941 - 2.083 0.312 - 575.1 1 2 0 0.0028 8 0 0 0 5.30E+07 3.40E+07 - - - 3.5577 0.9932 230117_WJC_METTL3_WT_vs_EV_F06.17766.17766.2 0.12 12-Jun R.ISPWLLR.V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 883.528 0.21 50262 17766 2 883.530246 442.7713 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3483.9 - 2.22E+06 - - - 2.5726 - 1.309 0.151 - 125.7 1 2 0 0.0023 7 0 0 0 2.34E+07 1.12E+08 - - - 1.0087 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.17767.17767.2 0.261 14-Sep K.NVFNALIR[166.11].L "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 955.5479 1.15 50263 17767 2 955.549933 478.7812 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 9.75 3484 - 2.08E+06 - - - 2.159 - 1.378 0.236 - 295.6 1 2 0 0.0021 8 0 0 0 5.35E+07 4.67E+07 - - - 1.7505 1 230117_WJC_METTL3_WT_vs_EV_F06.17768.17768.2 3.23E-05 18-Nov K.IIQLLDDYPK.C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1216.6703 1.05 50264 17768 2 1216.671407 609.3424 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3484.1 - 1.23E+06 - - - 0.877 - 2.459 0.522 - 397.6 1 2 0 0.0011 10 0 0 0 5.46E+08 5.19E+08 - - - 5.4076 0.994 230117_WJC_METTL3_WT_vs_EV_F06.17774.17774.2 0.011 12-Jun R.IIFDDFR.E sp|P46977|STT3A_HUMAN 1 924.4705 0.63 50270 17774 2 924.473202 463.2425 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.21 3484.9 - 453923 - - - 2.9033 - 1.297 0.189 - 82.4 1 2 0 0.0027 7 0 0 0 4.00E+06 6.37E+06 - - - 1.2601 0.861 230117_WJC_METTL3_WT_vs_EV_F06.17776.17776.2 18.2 12-May K.LFLDSLR[166.11].K "sp|P21359|NF1_HUMAN,sp|Q8N456|LRC18_HUMAN,sp|Q96EK5|KBP_HUMAN,tr|A0A6Q8PHL8|A0A6Q8PHL8_HUMAN,tr|J3KSB5|J3KSB5_HUMAN,tr|A0A6Q8PGG2|A0A6Q8PGG2_HUMAN,tr|A0A1B0GUA3|A0A1B0GUA3_HUMAN,tr|A0A6Q8PH45|A0A6Q8PH45_HUMAN" 8 872.4995 0.87 50272 17776 2 872.502367 437.257 Neurofibromin OS=Homo sapiens OX=9606 GN=NF1 PE=1 SV=2 5.84 3485.2 - 323538 - - - 3.2596 - 1.114 0.034 - 58 10 2 0 0.0028 7 0 0 0 3.56E+06 4.10E+06 - - - -0.8134 0.8651 230117_WJC_METTL3_WT_vs_EV_F06.17777.17777.2 0.507 12-Jul F.GLAYLFR.K "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|H7C3W8|H7C3W8_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 838.4701 1.55 50273 17777 2 838.47123 420.2423 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.75 3485.3 - 300301 - - - 1.3191 - 1.492 0.193 - 139 1 1 0 0.0011 7 0 0 0 5.56E+06 3.59E+06 - - - 1.7339 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.17781.17781.2 0.0213 14-Jun R.AFFSSYLK[136.11].S "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 969.5051 0.86 50276 17781 2 969.507978 485.7598 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.63 3485.8 - 891560 - - - 2.9489 - 1.25 0.356 - 89.2 1 2 0 0.0029 8 0 0 0 1.32E+07 1.54E+07 - - - 2.3425 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17783.17783.2 0.000463 18-Sep K.IIQLLDDYPK[136.11].C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1224.6845 1.05 50277 17783 2 1224.686518 613.3495 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3486 - 2.81E+06 - - - 1.6151 - 2.034 0.458 - 249.4 1 2 0 0.002 10 0 0 0 5.46E+08 5.19E+08 - - - 4.405 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17788.17788.2 3.23E-05 18-Sep R.FGFGFGNGMK[136.11].Q "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 8 1068.4942 0.63 50282 17788 2 1068.495916 535.2544 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 8.75 3486.5 - 355221 - - - 1.5714 - 1.541 0.518 - 137.3 1 2 0 0.0017 10 0 0 0 6.31E+06 9.97E+06 - - - 4.0735 0.9961 230117_WJC_METTL3_WT_vs_EV_F06.17791.17791.2 0.588 14-Jun R.DILIDPIR[166.11].V "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 963.5629 1.67 50283 17791 2 963.565063 482.7887 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3486.9 - 1.94E+06 - - - 2.2946 - 1.463 0.156 - 152.8 1 2 0 0.0022 8 0 0 0 3.12E+07 1.86E+07 - - - 1.3401 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.17792.17792.2 0.000304 16-Jul K.AENPYLFLR[166.11].G "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN" 2 1131.5952 1.72 50284 17792 2 1131.594493 566.8049 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 6.05 3487 - 1.57E+06 - - - -0.638 - 1.57 0.45 - 210.2 1 2 0 -0.0007 9 0 0 0 1.25E+07 7.26E+06 - - - 3.6695 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17796.17796.2 1.07 14-Aug R.IVEVLLIK.D "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 925.6212 1.13 50288 17796 2 925.622349 463.8179 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6 3487.2 - 1.65E+06 - - - 1.2359 - 1.856 0.306 - 117.9 1 2 0 0.0011 8 0 0 0 2.20E+07 1.95E+07 - - - 3.1659 0.999 230117_WJC_METTL3_WT_vs_EV_F06.17798.17798.2 0.000484 18-Jul R.LMDEAVLALR.N sp|Q92616|GCN1_HUMAN 1 1129.6165 0.64 50290 17798 2 1129.620262 565.8155 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3487.3 - 1.57E+06 - - - 3.3038 - 1.646 0.399 - 147.9 1 2 0 0.0037 10 0 0 0 9.40E+06 1.47E+07 - - - 3.3779 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.17799.17799.2 0.00153 18-Jun R.LMDEAVLALR[166.11].N sp|Q92616|GCN1_HUMAN 1 1139.6248 0.66 50291 17799 2 1139.627125 570.8197 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3487.4 - 1.43E+06 - - - 2.0401 - 1.465 0.383 - 85.5 1 2 0 0.0023 10 0 0 0 1.10E+07 1.67E+07 - - - 2.935 0.995 230117_WJC_METTL3_WT_vs_EV_F06.17804.17804.3 0.0688 Jul-40 K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 9.99 50294 17804 3 1204.681761 402.5678 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3488 - 1.51E+06 - - - 0.1561 - 1.542 0.212 - 57.8 1 2 0 0.0002 11 0 0 0 2.45E+07 2.45E+06 - - - 2.1338 0.9812 230117_WJC_METTL3_WT_vs_EV_F06.17807.17807.2 0.0889 May-32 R.ASSGGGAGGAAGYAPVK.Y sp|P25067|CO8A2_HUMAN 1 1376.6684 2.67 50297 17807 2 1376.66903 689.3415 Collagen alpha-2(VIII) chain OS=Homo sapiens OX=9606 GN=COL8A2 PE=1 SV=2 8.63 3488.3 - 586379 - - - 0.4271 - 1.186 0.156 - 33 10 2 0 0.0006 17 0 0 0 3.13E+07 1.17E+07 - - - 0.1657 1 230117_WJC_METTL3_WT_vs_EV_F06.17813.17813.2 7.71E-07 18-Nov R.EC[160.03]LNLWGYER.V sp|Q86U44|MTA70_HUMAN 1 1338.6027 84.02 50301 17813 2 1338.604127 670.3086 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3489.1 - 677289 - - - 1.0877 - 2.012 0.591 - 601.8 1 2 0 0.0015 10 0 0 0 1.11E+08 1.32E+06 - - - 5.3572 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.17821.17821.2 0.328 18-Aug K.SFIMSSTLIR.H sp|Q9UEG4|ZN629_HUMAN 1 1153.6165 1.49 50306 17821 2 1153.617313 577.8155 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.47 3490.1 - 688152 - - - 0.6787 - 1.247 0.221 - 140.6 1 2 0 0.0008 10 0 0 0 8.89E+06 5.96E+06 - - - 1.2892 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.17822.17822.2 3.24E-05 16-Oct K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 0.9 50307 17822 2 993.585132 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 3490.3 - 1.24E+06 - - - 0.4851 - 2.208 0.327 - 416.6 1 2 0 0.0005 9 0 0 0 3.08E+07 3.44E+07 - - - 3.7476 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.17832.17832.2 1.28 14-Sep R.IVEVLLIK[136.11].D "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 933.6354 1.13 50315 17832 2 933.634299 467.825 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6 3491.6 - 1.11E+06 - - - -1.1846 - 1.852 0.284 - 174.8 1 2 0 -0.0011 8 0 0 0 2.20E+07 1.95E+07 - - - 2.9969 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.17838.17838.2 0.000429 16-Sep K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 0.89 50319 17838 2 983.577252 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 3492.3 - 582419 - - - 0.8866 - 2.035 0.341 - 330.9 1 2 0 0.0009 9 0 0 0 3.08E+07 3.44E+07 - - - 3.6149 0.9937 230117_WJC_METTL3_WT_vs_EV_F06.17848.17848.2 0.000592 18-Aug R.FLLADNLYC[160.03]K[136.11].A sp|P61758|PFD3_HUMAN 1 1263.6413 3.46 50327 17848 2 1263.636244 632.8279 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 5.83 3493.5 - 701368 - - - -3.9972 - 1.815 0.418 - 193.7 1 2 0 -0.0051 10 0 0 0 5.11E+07 1.48E+07 - - - 3.7906 1 230117_WJC_METTL3_WT_vs_EV_F06.17854.17854.2 0.00225 18-Sep K.VEDAMLMFDK.T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|A0A6Q8PHP1|A0A6Q8PHP1_HUMAN" 6 1197.541 5.18 50331 17854 2 1197.542192 599.7778 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.03 3494.3 - 749071 - - - 1.0104 - 2.03 0.529 - 239.6 1 2 0 0.0012 10 0 0 0 2.35E+07 4.53E+06 - - - 4.9242 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.17856.17856.2 0.0921 18-Oct R.FLLADNLYC[160.03]K.A sp|P61758|PFD3_HUMAN 1 1255.6271 3.44 50333 17856 2 1255.629742 628.8208 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 5.83 3494.5 - 1.04E+06 - - - 2.1081 - 2.045 0.341 - 271.6 1 2 0 0.0026 10 0 0 0 5.10E+07 1.48E+07 - - - 3.5557 0.9744 230117_WJC_METTL3_WT_vs_EV_F06.17858.17858.2 0.215 16-Aug K.NFDMVIVYK[136.11].D sp|Q9Y5B9|SP16H_HUMAN 1 1135.5827 0.83 50335 17858 2 1135.579234 568.7986 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.83 3494.7 - 326646 - - - -3.0671 - 1.246 0.246 - 96.2 1 2 0 -0.0035 9 0 0 0 6.80E+06 8.24E+06 - - - 1.4932 0.9955 230117_WJC_METTL3_WT_vs_EV_F06.17865.17865.2 0.0196 14-Aug K.LASFFLSR.V "sp|Q8IZL8|PELP1_HUMAN,tr|E7EV54|E7EV54_HUMAN,tr|C9JFV4|C9JFV4_HUMAN,tr|I3L4P1|I3L4P1_HUMAN,tr|I3L445|I3L445_HUMAN" 5 939.5178 0.69 50340 17865 2 939.52197 470.7662 "Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2" 9.75 3495.6 - 1.07E+06 - - - 4.4363 - 1.636 0.258 - 193.5 1 2 0 0.0042 8 0 0 0 9.30E+06 1.34E+07 - - - 2.4299 0.9596 230117_WJC_METTL3_WT_vs_EV_F06.17867.17867.2 0.00177 20-Sep R.LVHPGVAEVVF.V "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1165.6495 - 50342 17867 2 1165.649216 583.832 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.24 3495.7 - 699709 - - - -0.2822 - 1.934 0.44 - 222.4 1 1 0 -0.0003 11 0 0 0 - - - - - 4.0751 1 230117_WJC_METTL3_WT_vs_EV_F06.17872.17872.2 7.03E-08 18-Dec K.VDDAMLMFDK.T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1183.5253 1.26 50345 17872 2 1183.529559 592.7699 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 3.93 3496.4 - 616088 - - - 3.5715 - 2.748 0.622 - 591.6 1 2 0 0.0042 10 0 0 0 2.94E+07 2.34E+07 - - - 6.4554 1 230117_WJC_METTL3_WT_vs_EV_F06.17874.17874.2 0.019 18-Nov K.VDDAMLMFDK[136.11].T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1191.5395 1.25 50347 17874 2 1191.541949 596.777 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 3.93 3496.6 - 571529 - - - 2.0285 - 2.634 0.533 - 482.8 1 2 0 0.0024 10 0 0 0 2.94E+07 2.34E+07 - - - 5.6804 1 230117_WJC_METTL3_WT_vs_EV_F06.17875.17875.2 2.77E-05 20-Nov R.YGLIGLNGIGK[136.11].S "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1111.6481 2.3 50348 17875 2 1111.650495 556.8313 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.59 3496.7 - 458528 - - - 2.159 - 2.248 0.543 - 281.2 1 2 0 0.0024 11 0 0 0 5.75E+07 2.50E+07 - - - 5.2422 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17877.17877.2 5.80E-05 16-Oct K.NFDMVIVYK.D sp|Q9Y5B9|SP16H_HUMAN 1 1127.5685 0.83 50350 17877 2 1127.571032 564.7915 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.83 3496.9 - 136654 - - - 2.2305 - 1.813 0.499 - 307.8 1 2 0 0.0025 9 0 0 0 6.85E+06 8.29E+06 - - - 4.4471 0.9965 230117_WJC_METTL3_WT_vs_EV_F06.17884.17884.2 0.0369 14-Aug R.LDTIFFAK[136.11].Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 961.5364 2.48 50355 17884 2 961.535704 481.7755 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3497.7 - 220580 - - - -0.7436 - 1.709 0.177 - 141.2 1 2 0 -0.0007 8 0 0 0 1.16E+08 4.68E+07 - - - 1.9644 1 230117_WJC_METTL3_WT_vs_EV_F06.17886.17886.2 2.72E-07 24-Sep K.VLATTFDPYLGGR.N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1408.7351 11.53 50357 17886 2 1408.737303 705.3748 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3498 - 168909 - - - 1.5887 - 2.337 0.61 - 185.2 1 2 0 0.0022 13 0 0 0 5.12E+07 4.44E+06 - - - 5.7244 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.17889.17889.2 0.0103 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 628.3 50359 17889 2 1006.572755 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3498.3 - 2.83E+06 - - - 2.8384 - 1.989 0.478 - 254.6 1 2 0 0.0029 9 0 0 0 1.01E+08 1.61E+05 - - - 4.56 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.17891.17891.2 0.0611 14-Aug R.LDTIFFAK.Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 953.5222 2.47 50360 17891 2 953.523487 477.7684 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3498.6 - 1.51E+06 - - - 1.3298 - 1.804 0.174 - 169.4 1 2 0 0.0013 8 0 0 0 1.28E+08 5.19E+07 - - - 2.1052 0.9948 230117_WJC_METTL3_WT_vs_EV_F06.17893.17893.2 0.0147 14-Aug K.LILTPFER.N "sp|Q9H089|LSG1_HUMAN,tr|F8WFC6|F8WFC6_HUMAN" 2 987.5753 1.26 50362 17893 2 987.579734 494.7949 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 6 3498.8 - 2.06E+06 - - - 4.4726 - 1.973 0.165 - 206.7 1 2 0 0.0044 8 0 0 0 3.78E+07 3.01E+07 - - - 2.3078 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.17895.17895.2 0.0142 14-Sep R.LSVLLGLK.K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 841.5637 2.48 50364 17895 2 841.567344 421.7891 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3499 - 400324 - - - 4.3419 - 1.973 0.326 - 206.6 1 2 0 0.0037 8 0 0 0 6.21E+06 2.50E+06 - - - 3.4972 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.17898.17898.2 0.0488 14-Jul R.LSVLLGLK[136.11].K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 849.5779 2.48 50367 17898 2 849.581145 425.7962 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3499.4 - 182952 - - - 3.8313 - 1.649 0.266 - 95.2 1 2 0 0.0033 8 0 0 0 6.21E+06 2.50E+06 - - - 2.5131 1 230117_WJC_METTL3_WT_vs_EV_F06.17900.17900.2 1.02E-10 30-Dec K.VLAQNSGFDLQETLVK.L sp|P40227|TCPZ_HUMAN 1 1760.9309 25.93 50369 17900 2 1760.933588 881.4727 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3499.7 - 121932 - - - 1.5463 - 2.456 0.642 - 390.9 1 2 0 0.0027 16 0 0 0 2.13E+06 8.22E+04 - - - 5.991 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.17904.17904.2 0.189 14-Jul R.ADLIAYLK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 905.5222 1.72 50371 17904 2 905.524374 453.7684 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 5.88 3500.1 - 972825 - - - 2.3798 - 1.274 0.205 - 131.7 1 2 0 0.0022 8 0 0 0 2.55E+07 1.48E+07 - - - 1.2848 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.17905.17905.2 0.092 14-Aug R.ADLIAYLK[136.11].K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 913.5364 1.67 50372 17905 2 913.53826 457.7755 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 5.88 3500.3 - 412642 - - - 2.0152 - 1.637 0.182 - 171.7 1 2 0 0.0018 8 0 0 0 2.59E+07 1.55E+07 - - - 1.8711 0.9777 230117_WJC_METTL3_WT_vs_EV_F06.17907.17907.2 0.22 14-Aug R.GIFEPFGR.L "sp|Q14498|RBM39_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 5 921.4709 0.8 50374 17907 2 921.475078 461.7427 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 6 3500.5 - 593611 - - - 4.5861 - 1.529 0.104 - 195.7 1 2 0 0.0042 8 0 0 0 5.40E+07 6.74E+07 - - - 1.0884 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.17908.17908.3 0.0479 15/36 R.FSVLLLHGIR.F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1153.6972 2.55 50375 17908 3 1153.701728 385.573 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3500.7 - 525359 - - - 3.956 - 1.991 0.338 - 263.3 1 2 0 0.0046 10 0 0 0 1.15E+07 4.49E+06 - - - 4.3182 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.17911.17911.3 0.153 Nov-36 R.FSVLLLHGIR[166.11].F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1163.7054 2.55 50378 17911 3 1163.709693 388.9091 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3501.1 - 226721 - - - 3.6599 - 2.181 0.207 - 109.4 1 2 0 0.0043 10 0 0 0 1.15E+07 4.49E+06 - - - 3.124 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.17917.17917.2 0.000429 18-Jul R.LITTQQWLIK.L sp|P00846|ATP6_HUMAN 1 1242.7336 1.11 50384 17917 2 1242.737965 622.3741 ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1 8.75 3501.8 - 133521 - - - 3.5052 - 1.635 0.46 - 105.5 1 2 0 0.0044 10 0 0 0 6.83E+06 6.13E+06 - - - 3.8095 0.9361 230117_WJC_METTL3_WT_vs_EV_F06.17919.17919.2 0.141 20-Jun R.C[160.03]LAPMMSEVIR.L "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 1305.6243 2.26 50386 17919 2 1305.635066 653.8194 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 5.99 3502.1 - 117284 - - - 8.2191 - 1.368 0.286 - 116.3 1 2 0 0.0107 11 0 0 0 2.60E+06 1.15E+06 - - - 1.9977 0.9825 230117_WJC_METTL3_WT_vs_EV_F06.17921.17921.2 0.289 24-Sep R.LPLLPPESPGPLR.Q "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN,tr|A0A669KAX5|A0A669KAX5_HUMAN" 6 1384.8078 1.29 50388 17921 2 1384.816532 693.4112 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 6 3502.4 - 87942.2 - - - 6.2796 - 1.934 0.214 - 244.9 1 2 0 0.0087 13 0 0 0 1.10E+06 8.50E+05 - - - 2.3117 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.17925.17925.2 0.00133 16-Sep R.AVALYFIDK[136.11].L "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN,tr|E5RIC7|E5RIC7_HUMAN" 4 1046.5892 0.89 50391 17925 2 1046.593169 524.3019 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 5.88 3502.9 - 3.67E+06 - - - 3.8086 - 1.867 0.4 - 289.5 1 2 0 0.004 9 0 0 0 2.92E+07 3.28E+07 - - - 3.8004 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17929.17929.2 0.0116 16-Jul R.FLSPEFIPR.R "sp|P49406|RM19_HUMAN,tr|A0A0A0MRF4|A0A0A0MRF4_HUMAN" 2 1104.5968 0.96 50395 17929 2 1104.597095 553.3057 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 6 3503.2 - 2.08E+06 - - - 0.2843 - 1.529 0.403 - 168.6 1 2 0 0.0003 9 0 0 0 2.45E+07 2.56E+07 - - - 3.2459 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.17930.17930.2 1.06 14-Sep K.ILILQGLK.Q "sp|Q9UNX4|WDR3_HUMAN,tr|D6RCT0|D6RCT0_HUMAN" 2 896.6059 0.96 50396 17930 2 896.607021 449.3102 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 8.75 3503.2 - 1.89E+06 - - - 1.2625 - 1.46 0.17 - 214.4 1 2 0 0.0011 8 0 0 0 1.92E+07 1.99E+07 - - - 1.4376 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.17931.17931.2 0.00147 16-Sep K.IIGNLLYYR.Y "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1123.639 1.18 50397 17931 2 1123.642704 562.8268 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.59 3503.3 - 1.72E+06 - - - 3.3142 - 1.79 0.316 - 161.4 1 2 0 0.0037 9 0 0 0 3.46E+07 2.93E+07 - - - 3.0582 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.17932.17932.2 0.000956 13/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 4.69 50398 17932 2 1484.910494 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3503.4 - 600580 - - - 1.757 - 2.148 0.472 - 387 1 2 0 0.0026 15 0 0 0 9.08E+06 1.94E+06 - - - 4.406 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.17933.17933.2 0.00148 18-Oct R.LITTQQWLIK[136.11].L sp|P00846|ATP6_HUMAN 1 1250.7478 1.11 50399 17933 2 1250.753138 626.3812 ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1 8.75 3503.5 - 389223 - - - 4.2607 - 1.944 0.461 - 296.8 1 2 0 0.0053 10 0 0 0 6.83E+06 6.13E+06 - - - 4.2998 0.9959 230117_WJC_METTL3_WT_vs_EV_F06.17937.17937.2 0.571 16-Jun K.AVIILVPVR.L "sp|Q96DT6|ATG4C_HUMAN,tr|H7BZW5|H7BZW5_HUMAN" 2 978.659 0.9 50403 17937 2 978.660946 490.3368 Cysteine protease ATG4C OS=Homo sapiens OX=9606 GN=ATG4C PE=1 SV=1 9.79 3504 - 166182 - - - 2.0017 - 1.175 0.231 - 52.8 1 2 0 0.002 9 0 0 0 9.40E+05 1.04E+06 - - - 1.2131 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.17940.17940.2 0.000439 16-Oct K.IIGNLLYYR[166.11].Y "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1133.6472 1.18 50404 17940 2 1133.652954 567.8309 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.59 3504.5 - 5.13E+06 - - - 5.0315 - 2.089 0.359 - 251.6 1 2 0 0.0057 9 0 0 0 3.46E+07 2.93E+07 - - - 3.8221 0.9633 230117_WJC_METTL3_WT_vs_EV_F06.17942.17942.2 1.72 14-May K.ILILQGLK[136.11].Q "sp|Q9UNX4|WDR3_HUMAN,tr|D6RCT0|D6RCT0_HUMAN" 2 904.6201 0.96 50406 17942 2 904.622822 453.3173 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 8.75 3504.6 - 4.73E+06 - - - 3.0212 - 1.136 0.12 - 41.3 5 2 0 0.0027 8 0 0 0 1.92E+07 1.99E+07 - - - -0.0012 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.17943.17943.2 0.00374 18-Jul R.IC[160.03]DDELILIK.N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1230.653 9.82 50407 17943 2 1230.657029 616.3338 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3504.6 - 3.35E+06 - - - 3.2934 - 1.472 0.351 - 97.8 1 2 0 0.0041 10 0 0 0 6.81E+08 6.94E+07 - - - 2.7114 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.17944.17944.2 0.00149 20-Oct R.LLALNSLYSPK.L sp|P78527|PRKDC_HUMAN 1 1217.702 1.21 50408 17944 2 1217.707551 609.8583 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.59 3504.7 - 2.02E+06 - - - 4.5799 - 2.109 0.373 - 246.6 1 2 0 0.0056 11 0 0 0 4.77E+07 3.95E+07 - - - 3.8129 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.17945.17945.2 0.000115 20-Sep R.LLALNSLYSPK[136.11].L sp|P78527|PRKDC_HUMAN 1 1225.7162 1.21 50409 17945 2 1225.723072 613.8654 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.59 3504.7 - 1.93E+06 - - - 5.6277 - 2.005 0.466 - 187.5 1 2 0 0.0069 11 0 0 0 4.77E+07 3.95E+07 - - - 4.3626 0.9969 230117_WJC_METTL3_WT_vs_EV_F06.17950.17950.2 0.1 14-Aug K.NILTEIYR.L sp|Q15907|RB11B_HUMAN 1 1020.5604 1.56 50413 17950 2 1020.56381 511.2875 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 6 3505.3 - 234852 - - - 3.3462 - 1.424 0.265 - 187.4 1 2 0 0.0034 8 0 0 0 4.65E+07 2.99E+07 - - - 2.0633 0.9956 230117_WJC_METTL3_WT_vs_EV_F06.17955.17955.2 0.0428 28-Jul R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 9.19 50418 17955 2 1494.92051 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3505.8 - 92677.2 - - - 2.9132 - 1.516 0.216 - 98.2 2 2 0 0.0044 15 0 0 0 2.29E+07 2.49E+06 - - - 1.5235 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.17958.17958.2 5.82E-06 20-Sep R.AVVPSYIPLVK[136.11].K sp|P36551|HEM6_HUMAN 1 1192.7311 1.11 50419 17958 2 1192.734707 597.3728 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3506.2 - 2.50E+06 - - - 3.0275 - 2.066 0.379 - 259.5 1 2 0 0.0036 11 0 0 0 1.34E+08 1.20E+08 - - - 3.8021 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17959.17959.2 1.28E-05 20-Oct R.AVVPSYIPLVK.K sp|P36551|HEM6_HUMAN 1 1184.7169 1.11 50420 17959 2 1184.720592 593.3657 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3506.3 - 2.30E+06 - - - 3.1197 - 1.808 0.473 - 367.4 1 2 0 0.0037 11 0 0 0 1.34E+08 1.20E+08 - - - 4.1355 1 230117_WJC_METTL3_WT_vs_EV_F06.17960.17960.2 2.45E-06 14/18 R.IC[160.03]DDELILIK[136.11].N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1238.6672 9.78 50421 17960 2 1238.672256 620.3409 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3506.4 - 769119 - - - 4.1012 - 2.723 0.428 - 445.6 1 2 0 0.0051 10 0 0 0 6.75E+08 6.90E+07 - - - 4.9968 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.17961.17961.2 0.149 18-Nov K.EVLLVALGSR.Q sp|Q10570|CPSF1_HUMAN 1 1055.6339 1.42 50422 17961 2 1055.638382 528.8242 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6.1 3506.5 - 712316 - - - 4.2505 - 2.325 0.281 - 409.5 1 2 0 0.0045 10 0 0 0 1.31E+07 9.21E+06 - - - 3.4701 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.17962.17962.2 0.000156 18-Sep K.VLALLDVPDK[136.11].S sp|Q9NX62|IMPA3_HUMAN 1 1089.6525 0.93 50423 17962 2 1089.656469 545.8335 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.21 3506.7 - 606050 - - - 3.6324 - 1.845 0.257 - 199.2 1 2 0 0.004 10 0 0 0 3.60E+07 3.85E+07 - - - 2.6476 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.17972.17972.2 0.576 18-Sep K.VLALLDVPDK.S sp|Q9NX62|IMPA3_HUMAN 1 1081.6383 0.91 50432 17972 2 1081.642037 541.8264 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.21 3508 - 815369 - - - 3.4448 - 2.018 0.192 - 236.9 1 2 0 0.0037 10 0 0 0 3.50E+07 3.84E+07 - - - 2.4177 0.998 230117_WJC_METTL3_WT_vs_EV_F06.17974.17974.2 0.0282 14-Sep R.LFGALLER[166.11].G sp|Q9BVI4|NOC4L_HUMAN 1 927.5417 1.05 50434 17974 2 927.545296 464.7781 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3508.2 - 4.51E+06 - - - 3.8532 - 2.129 0.217 - 286.7 1 2 0 0.0036 8 0 0 0 5.27E+07 5.03E+07 - - - 2.9217 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.17977.17977.2 0.00149 20-Dec K.VLTPELYAELR[166.11].A "sp|P12277|KCRB_HUMAN,tr|G3V461|G3V461_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 3 1312.7266 0.87 50437 17977 2 1312.725681 657.3706 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.53 3508.5 - 992440 - - - -0.7176 - 2.324 0.402 - 495.3 1 2 0 -0.0009 11 0 0 0 3.48E+07 4.02E+07 - - - 4.2912 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.17978.17978.2 0.0468 16-Sep R.LLESMIPIK[136.11].M "sp|Q9GZM5|YIPF3_HUMAN,tr|D6RGY8|D6RGY8_HUMAN,tr|E7EQR8|E7EQR8_HUMAN,tr|H0Y9A1|H0Y9A1_HUMAN,tr|D6RFI3|D6RFI3_HUMAN" 5 1050.6239 2 50438 17978 2 1050.628251 526.3192 Protein YIPF3 OS=Homo sapiens OX=9606 GN=YIPF3 PE=1 SV=1 6 3508.6 - 752294 - - - 4.1851 - 1.672 0.315 - 209.5 1 2 0 0.0044 9 0 0 0 1.95E+07 9.71E+06 - - - 2.8533 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.17980.17980.2 5.36E-05 20-Nov K.VLTPELYAELR.A "sp|P12277|KCRB_HUMAN,tr|G3V461|G3V461_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 3 1302.7184 0.86 50440 17980 2 1302.721203 652.3665 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.53 3508.8 - 494066 - - - 2.1877 - 2.299 0.387 - 544 1 2 0 0.0029 11 0 0 0 3.47E+07 4.02E+07 - - - 4.1505 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.17991.17991.2 0.0316 14-Aug R.LFGALLER.G sp|Q9BVI4|NOC4L_HUMAN 1 917.5335 1.03 50449 17991 2 917.536373 459.774 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3510.2 - 6.92E+06 - - - 3.1835 - 1.748 0.24 - 185.9 1 2 0 0.0029 8 0 0 0 5.45E+07 5.29E+07 - - - 2.497 0.9569 230117_WJC_METTL3_WT_vs_EV_F06.17992.17992.2 0.000864 18-Oct G.AGALQVVGLK[136.11].T sp|Q9P1Q0|VPS54_HUMAN 1 962.6004 2.05 50450 17992 2 962.602994 482.3075 Vacuolar protein sorting-associated protein 54 OS=Homo sapiens OX=9606 GN=VPS54 PE=1 SV=2 8.8 3510.2 - 5.17E+06 - - - 2.6782 - 1.841 0.398 - 231.5 1 1 0 0.0026 10 0 0 0 1.74E+08 8.47E+07 - - - 3.6834 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.17994.17994.2 0.119 16-Sep R.SSIAGLLLK.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 900.5644 3.59 50452 17994 2 900.567195 451.2895 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.47 3510.4 - 2.16E+06 - - - 3.0836 - 1.706 0.257 - 195.5 1 2 0 0.0028 9 0 0 0 2.11E+07 5.87E+06 - - - 2.4837 0.9944 230117_WJC_METTL3_WT_vs_EV_F06.17997.17997.2 0.262 16-Aug R.SSIAGLLLK[136.11].A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 908.5786 3.56 50455 17997 2 908.58128 455.2966 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.47 3510.8 - 1.24E+06 - - - 2.9299 - 1.324 0.2 - 100.3 1 2 0 0.0027 9 0 0 0 2.09E+07 5.87E+06 - - - 1.3293 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.17998.17998.2 0.0137 18-Sep K.EVLLVALGSR[166.11].Q sp|Q10570|CPSF1_HUMAN 1 1065.6422 1.43 50456 17998 2 1065.645116 533.8284 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6.1 3510.9 - 915963 - - - 2.7692 - 1.598 0.333 - 230.1 1 2 0 0.003 10 0 0 0 1.31E+07 9.21E+06 - - - 2.808 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18000.18000.2 0.00338 22-Aug R.IGPLSPFTNAYR[166.11].R "sp|O75486|SUPT3_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 2 1344.7066 1.72 50458 18000 2 1344.709782 673.3606 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 8.75 3511.2 - 815878 - - - 2.399 - 1.868 0.4 - 108.5 1 2 0 0.0032 12 0 0 0 1.47E+07 8.54E+06 - - - 3.6385 1 230117_WJC_METTL3_WT_vs_EV_F06.18002.18002.2 5.64E-14 18/38 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 11.29 50460 18002 2 2187.044484 1094.5262 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3511.4 - 599764 - - - 3.026 - 3.519 0.734 - 892.8 1 2 0 0.0066 20 0 0 0 3.00E+06 2.65E+05 - - - 7.5535 1 230117_WJC_METTL3_WT_vs_EV_F06.18006.18006.2 5.62E-05 22-Dec K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 999 50464 18006 2 1474.744097 738.3781 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3511.9 - 307867 - - - 1.6884 - 2.671 0.556 - 579.5 1 2 0 0.0025 12 0 0 0 3.70E+06 0.00E+00 - - - 5.7318 0.9816 230117_WJC_METTL3_WT_vs_EV_F06.18007.18007.2 0.837 12-Jun K.FLELLPK.D "sp|P63010|AP2B1_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 5 858.5215 1.75 50465 18007 2 858.524195 430.268 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 6 3512.1 - 269534 - - - 3.1496 - 1.265 0.119 - 118.9 2 2 0 0.0027 7 0 0 0 2.84E+07 1.62E+07 - - - 0.5295 0.9791 230117_WJC_METTL3_WT_vs_EV_F06.18008.18008.3 0.309 Jul-40 R.AVVPSYIPLVK[136.11].K sp|P36551|HEM6_HUMAN 1 1192.7311 1.01 50466 18008 3 1192.731876 398.5843 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3512.2 - 166073 - - - 0.654 - 1.263 0.166 - 46.1 1 2 0 0.0008 11 0 0 0 9.88E+05 9.77E+05 - - - 1.0538 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.18009.18009.2 0.119 22-Dec R.LLQTIAVLEAQR.S sp|Q8IYH5|ZZZ3_HUMAN 1 1353.798 4.59 50467 18009 2 1353.797001 677.9063 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 6 3512.3 - 164067 - - - -0.7379 - 2.355 0.355 - 555.7 1 2 0 -0.001 12 0 0 0 3.05E+06 6.64E+05 - - - 3.9164 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.18015.18015.2 0.595 16-Sep R.VILLENLTR.F "sp|Q14999|CUL7_HUMAN,tr|A0A669KB95|A0A669KB95_HUMAN,tr|A0A669KAU7|A0A669KAU7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 4 1069.6495 1.58 50472 18015 2 1069.651856 535.832 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 5.97 3512.9 - 858110 - - - 2.1605 - 1.823 0.307 - 224.2 1 2 0 0.0023 9 0 0 0 1.16E+07 7.30E+06 - - - 3.045 1 230117_WJC_METTL3_WT_vs_EV_F06.18016.18016.2 1.53E-05 18-Nov R.VVYIFGPPVK.E sp|P49915|GUAA_HUMAN 1 1117.6536 3.27 50473 18016 2 1117.65626 559.8341 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 8.56 3513 - 856729 - - - 2.4086 - 2.086 0.519 - 515.6 1 2 0 0.0027 10 0 0 0 1.45E+07 4.44E+06 - - - 4.9258 0.9922 230117_WJC_METTL3_WT_vs_EV_F06.18017.18017.2 0.214 14-Aug R.DVDFELIK.V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 977.507 3.68 50474 18017 2 977.51085 489.7608 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3513.1 - 567057 - - - 3.9764 - 1.325 0.233 - 178.7 1 2 0 0.0039 8 0 0 0 9.12E+08 2.48E+08 - - - 1.6094 0.9929 230117_WJC_METTL3_WT_vs_EV_F06.18021.18021.2 8.28 12-Jul R.LLDFLQK.R "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 875.5117 1.45 50478 18021 2 875.51261 438.7631 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.84 3513.6 - 148492 - - - 1.0919 - 1.266 0.126 - 107.5 1 2 0 0.001 7 0 0 0 7.51E+07 5.17E+07 - - - 0.7187 0.997 230117_WJC_METTL3_WT_vs_EV_F06.18023.18023.2 0.294 14-Aug K.IDHILDAL.- "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 908.4967 - 50479 18023 2 908.4986 455.2556 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.2 3513.9 - 1.60E+07 - - - 2.055 - 1.555 0.151 - 208.5 1 2 0 0.0019 8 0 0 0 - - - - - 1.4872 0.9601 230117_WJC_METTL3_WT_vs_EV_F06.18036.18036.2 1.29 14-Jul R.LYPVLLVK.Q "sp|Q7Z7F7|RM55_HUMAN,tr|X6RIW1|X6RIW1_HUMAN" 2 943.6106 1.11 50489 18036 2 943.614363 472.8126 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 8.59 3515.2 - 1.23E+06 - - - 3.9455 - 1.079 0.145 - 137.1 1 2 0 0.0037 8 0 0 0 2.29E+07 2.08E+07 - - - 0.3401 0.9865 230117_WJC_METTL3_WT_vs_EV_F06.18038.18038.2 0.0741 16-Oct R.TLADIIMEK.L "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1032.5525 0.5 50491 18038 2 1032.548565 517.2835 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.37 3515.4 - 776650 - - - -3.8429 - 1.585 0.299 - 269.7 1 2 0 -0.004 9 0 0 0 2.19E+07 4.42E+07 - - - 2.5807 1 230117_WJC_METTL3_WT_vs_EV_F06.18041.18041.2 7.06E-05 16-Oct R.LSMMLLDSR[166.11].A "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1074.5441 4.87 50494 18041 2 1074.549515 538.2793 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.84 3515.7 - 459103 - - - 5.0328 - 2.131 0.462 - 335.5 1 2 0 0.0054 9 0 0 0 7.13E+07 1.47E+07 - - - 4.6405 0.9959 230117_WJC_METTL3_WT_vs_EV_F06.18044.18044.2 0.0005 20-Oct R.LLMLGLDNAGK.T "sp|P36404|ARL2_HUMAN,tr|V9GYD0|V9GYD0_HUMAN" 2 1143.6322 112.35 50497 18044 2 1143.638084 572.8234 ADP-ribosylation factor-like protein 2 OS=Homo sapiens OX=9606 GN=ARL2 PE=1 SV=4 5.84 3516.1 - 258032 - - - 5.1625 - 1.813 0.338 - 212.7 1 2 0 0.0059 11 0 0 0 4.79E+08 4.26E+06 - - - 3.1452 1 230117_WJC_METTL3_WT_vs_EV_F06.18046.18046.2 2.16E-07 20-Oct R.FPC[160.03]VVYINEVR.V sp|Q69YN4|VIR_HUMAN 1 1394.7017 2.68 50499 18046 2 1394.70404 698.3581 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 5.99 3516.4 - 159199 - - - 1.7086 - 2.009 0.544 - 411.5 1 2 0 0.0024 11 0 0 0 2.12E+06 7.93E+05 - - - 4.9455 0.9908 230117_WJC_METTL3_WT_vs_EV_F06.18049.18049.2 0.205 14-Aug R.DVDFELIK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 985.5212 5.47 50500 18049 2 985.524448 493.7679 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3516.8 - 4.66E+06 - - - 3.3333 - 1.193 0.211 - 162.3 1 2 0 0.0033 8 0 0 0 8.43E+08 1.54E+08 - - - 1.1306 0.9589 230117_WJC_METTL3_WT_vs_EV_F06.18051.18051.2 0.54 12-Aug R.LLDFLQK[136.11].R "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 883.5259 1.45 50502 18051 2 883.52961 442.7702 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.84 3517.1 - 2.51E+06 - - - 4.2511 - 1.534 0.009 - 139.4 1 2 0 0.0038 7 0 0 0 7.51E+07 5.17E+07 - - - 0.4621 0.9778 230117_WJC_METTL3_WT_vs_EV_F06.18052.18052.2 0.0978 16-Aug R.VVLPYLVPK.L sp|Q92616|GCN1_HUMAN 1 1026.6478 1.13 50503 18052 2 1026.653403 514.3312 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.56 3517.2 - 592996 - - - 5.5024 - 1.41 0.212 - 186.1 1 2 0 0.0056 9 0 0 0 4.01E+07 3.54E+07 - - - 1.5991 1 230117_WJC_METTL3_WT_vs_EV_F06.18054.18054.2 2.17E-07 13/22 K.LFVTNDAATILR[166.11].E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1342.7484 7.92 50505 18054 2 1342.752137 672.3815 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3517.4 - 461590 - - - 2.7675 - 2.607 0.494 - 548.7 1 2 0 0.0037 12 0 0 0 5.15E+09 6.50E+08 - - - 5.2097 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18062.18062.2 0.00101 14-Nov K.LDYILGLK[136.11].L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 941.5677 0.77 50511 18062 2 941.569846 471.7911 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3518.4 - 1.13E+06 - - - 2.259 - 2.042 0.277 - 347.1 1 2 0 0.0021 8 0 0 0 3.87E+08 5.01E+08 - - - 3.2394 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.18067.18067.2 0.00389 14-Sep K.LDYILGLK.L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 933.5535 0.79 50514 18067 2 933.555793 467.784 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3519.1 - 1.51E+06 - - - 2.4359 - 1.802 0.309 - 276.6 1 2 0 0.0023 8 0 0 0 3.87E+08 4.92E+08 - - - 3.0986 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18071.18071.2 0.0122 16-Sep K.LFLVQLQEK[136.11].A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1124.6685 1.24 50518 18071 2 1124.669368 563.3415 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3519.6 - 215411 - - - 0.7753 - 1.782 0.337 - 179.8 1 2 0 0.0009 9 0 0 0 3.59E+07 2.90E+07 - - - 3.2012 1 230117_WJC_METTL3_WT_vs_EV_F06.18072.18072.2 0.00663 13/20 R.SALLVQLATAR.P "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1141.6819 2.39 50519 18072 2 1141.683804 571.8482 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 9.47 3519.7 - 182895 - - - 1.6607 - 2.658 0.465 - 573.2 1 1 0 0.0019 11 0 0 0 3.15E+07 1.32E+07 - - - 5.1195 0.9251 230117_WJC_METTL3_WT_vs_EV_F06.18077.18077.2 0.0858 18-Aug R.TIYWIDYIIR.H sp|Q16880|CGT_HUMAN 1 1354.7285 2.23 50522 18077 2 1354.723896 678.3715 2-hydroxyacylsphingosine 1-beta-galactosyltransferase OS=Homo sapiens OX=9606 GN=UGT8 PE=1 SV=2 5.5 3520.3 - 91983.6 - - - -3.4162 - 1.538 0.074 - 94.1 1 2 0 -0.0046 10 0 0 0 1.38E+07 6.20E+06 - - - 0.7877 0.9956 230117_WJC_METTL3_WT_vs_EV_F06.18080.18080.2 0.253 12-May R.GWLNIVR.H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 856.4919 1.69 50523 18080 2 856.492451 429.2532 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 9.75 3520.7 - 1.04E+06 - - - 0.6176 - 1.154 0.227 - 104.2 1 2 0 0.0005 7 0 0 0 2.26E+07 1.34E+07 - - - 1.1713 0.999 230117_WJC_METTL3_WT_vs_EV_F06.18081.18081.2 1.03 14-Jul R.LLILMEAR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 967.5764 1.58 50524 18081 2 967.577291 484.7955 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6 3520.9 - 748395 - - - 0.9281 - 1.593 0.264 - 164 1 2 0 0.0009 8 0 0 0 3.14E+07 1.98E+07 - - - 2.3949 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.18082.18082.2 0.0277 16-Aug K.LFLVQLQEK.A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1116.6543 1.24 50525 18082 2 1116.657878 559.3344 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3521 - 1.17E+06 - - - 3.2078 - 1.807 0.319 - 164.8 1 2 0 0.0036 9 0 0 0 3.59E+07 2.90E+07 - - - 3.1077 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.18083.18083.2 0.0475 20-Aug K.VLTILINPADR.A "sp|P52848|NDST1_HUMAN,tr|E7EVJ3|E7EVJ3_HUMAN" 2 1223.7238 1.58 50526 18083 2 1223.722996 612.8692 Bifunctional heparan sulfate N-deacetylase\N-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=NDST1 PE=1 SV=1 5.81 3521.1 - 242803 - - - -0.6341 - 1.706 0.286 - 150.6 1 2 0 -0.0008 11 0 0 0 6.56E+06 4.16E+06 - - - 2.5982 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.18094.18094.2 0.0941 16-Jul K.VLEALQVLR[166.11].C "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1049.6472 1.42 50533 18094 2 1049.648512 525.8309 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.97 3522.4 - 1.25E+06 - - - 1.2023 - 1.973 0.233 - 124.2 3 2 0 0.0013 9 0 0 0 5.84E+07 4.11E+07 - - - 2.5144 0.9935 230117_WJC_METTL3_WT_vs_EV_F06.18095.18095.2 0.326 16-Sep R.NFFGPEFVK.M sp|Q12923|PTN13_HUMAN 1 1083.5389 0.24 50534 18095 2 1083.541943 542.7767 Tyrosine-protein phosphatase non-receptor type 13 OS=Homo sapiens OX=9606 GN=PTPN13 PE=1 SV=2 6 3522.5 - 296471 - - - 2.7789 - 1.194 0.214 - 152.3 1 2 0 0.003 9 0 0 0 7.49E+06 3.10E+07 - - - 1.1336 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.18096.18096.2 2.03 16-Aug R.VVLPYLVPK[136.11].L sp|Q92616|GCN1_HUMAN 1 1034.662 1.13 50535 18096 2 1034.663713 518.3383 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.56 3522.7 - 1.31E+06 - - - 1.7001 - 1.308 0.175 - 192.8 1 2 0 0.0018 9 0 0 0 4.02E+07 3.54E+07 - - - 1.1098 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.18099.18099.2 0.913 14-Aug R.LLILMEAR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 957.5681 1.58 50536 18099 2 957.568121 479.7913 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6 3523.1 - 1.39E+06 - - - -0.0021 - 1.779 0.17 - 192.9 1 2 0 0 8 0 0 0 3.14E+07 1.98E+07 - - - 2.034 0.999 230117_WJC_METTL3_WT_vs_EV_F06.18101.18101.3 0.00347 Nov-44 K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 8.87 50538 18101 3 1332.743924 445.254 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3523.2 - 3.80E+06 - - - 2.831 - 2.031 0.275 - 144.5 1 2 0 0.0038 12 0 0 0 9.50E+07 1.07E+07 - - - 3.5689 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18103.18103.2 0.000735 18-Nov K.LAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1142.627 3.23 50540 18103 2 1142.628805 572.3208 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3523.3 - 1.20E+06 - - - 1.5491 - 2.057 0.356 - 480.6 1 2 0 0.0018 10 0 0 0 8.20E+08 2.54E+08 - - - 3.6831 0.8967 230117_WJC_METTL3_WT_vs_EV_F06.18104.18104.2 0.728 20-Jun K.VITC[160.03]GWDGLIK.L sp|O60508|PRP17_HUMAN 1 1260.6536 5.6 50541 18104 2 1260.648736 631.3341 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.8 3523.5 - 263054 - - - -3.8932 - 1.173 0.173 - 101.7 1 2 0 -0.0049 11 0 0 0 3.40E+06 6.06E+05 - - - 0.7489 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18108.18108.2 1.76E-05 16-Sep K.LLQDFFNGK.E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1080.5604 11.12 50544 18108 2 1080.561728 541.2875 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3523.9 - 474334 - - - 1.2336 - 1.825 0.507 - 207.6 1 2 0 0.0013 9 0 0 0 1.08E+08 9.75E+06 - - - 4.5257 1 230117_WJC_METTL3_WT_vs_EV_F06.18109.18109.2 4.77E-05 20-Nov K.LIVAYVDDLDR.R "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1290.682 1.5 50545 18109 2 1290.68077 646.3483 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 3.93 3524.1 - 300883 - - - -0.9274 - 2.175 0.513 - 512 1 2 0 -0.0012 11 0 0 0 1.09E+07 7.27E+06 - - - 4.9317 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18113.18113.2 0.00183 14-Oct R.VVDLLVIK.G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 897.5899 2.1 50547 18113 2 897.590326 449.8022 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3524.6 - 4.27E+06 - - - 0.469 - 1.664 0.491 - 276.2 1 2 0 0.0004 8 0 0 0 1.37E+08 6.52E+07 - - - 4.2032 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18114.18114.2 0.00412 16-Oct K.VLEALQVLR.C "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1039.639 1.42 50548 18114 2 1039.640054 520.8268 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.97 3524.6 - 4.46E+06 - - - 1.0331 - 2.008 0.399 - 342.4 1 2 0 0.0011 9 0 0 0 5.84E+07 4.11E+07 - - - 4.0045 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18118.18118.2 3.85E-05 16-Sep R.LIDFLEC[160.03]GK.T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1093.5478 0.83 50552 18118 2 1093.548558 547.7812 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3525.1 - 888470 - - - 0.7096 - 1.681 0.489 - 169.7 1 2 0 0.0008 9 0 0 0 1.83E+08 2.19E+08 - - - 4.1551 1 230117_WJC_METTL3_WT_vs_EV_F06.18123.18123.2 2.52E-05 22-Oct K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 7.93 50556 18123 2 1332.742575 667.3774 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3525.7 - 3.53E+08 - - - 1.8188 - 2.236 0.593 - 312.4 1 2 0 0.0024 12 0 0 0 5.14E+09 6.48E+08 - - - 5.5374 0.999 230117_WJC_METTL3_WT_vs_EV_F06.18125.18125.2 0.0137 18-Dec K.LAVNMVPFPR[166.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1152.6353 3.23 50557 18125 2 1152.636318 577.3249 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3525.9 - 1.98E+06 - - - 0.8789 - 1.848 0.234 - 596.7 1 2 0 0.001 10 0 0 0 8.19E+08 2.53E+08 - - - 2.4832 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18126.18126.2 0.00272 18-Oct K.YLAIAPPIIK.Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1097.6849 1.88 50558 18126 2 1097.685759 549.8497 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3526 - 971429 - - - 0.8117 - 1.666 0.418 - 352.9 1 2 0 0.0009 10 0 0 0 1.98E+08 1.05E+08 - - - 3.5528 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18127.18127.2 7.22E-05 14-Aug R.YQDILVFR.S "sp|P19623|SPEE_HUMAN,tr|K7EKM4|K7EKM4_HUMAN" 2 1052.5655 6.99 50559 18127 2 1052.567035 527.29 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.84 3526.1 - 2.78E+06 - - - 1.4764 - 1.77 0.404 - 193.7 1 2 0 0.0016 8 0 0 0 1.11E+08 1.59E+07 - - - 3.7465 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18133.18133.2 0.000123 16-Jul K.WEGNYLFPR[166.11].E "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 1190.5748 0.81 50565 18133 2 1190.577505 596.2947 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3526.7 - 225877 - - - 2.2611 - 1.431 0.425 - 133.8 1 2 0 0.0027 9 0 0 0 4.76E+06 5.86E+06 - - - 3.216 0.9238 230117_WJC_METTL3_WT_vs_EV_F06.18134.18134.2 0.765 20-Jun R.TINMQQSQVEK.Y "sp|Q8N6V9|TEX9_HUMAN,tr|H3BS88|H3BS88_HUMAN,tr|H0YLZ3|H0YLZ3_HUMAN" 3 1304.6395 8.02 50566 18134 2 1304.643946 653.327 Testis-expressed protein 9 OS=Homo sapiens OX=9606 GN=TEX9 PE=1 SV=1 5.66 3526.9 - 161735 - - - 3.4454 - 1.323 0.02 - 123.5 4 2 0 0.0045 11 0 0 0 8.39E+06 1.05E+06 - - - -0.3244 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.18138.18138.2 0.0391 12-Jun R.AVFWDIK.N sp|Q6P2Q9|PRP8_HUMAN 1 877.4698 1.24 50569 18138 2 877.471511 439.7422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3527.3 - 8.49E+06 - - - 1.9613 - 1.202 0.398 - 157.9 1 2 0 0.0017 7 0 0 0 8.85E+07 7.12E+07 - - - 2.5631 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18140.18140.2 0.00431 14-Sep R.VVDLLVIK[136.11].G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 905.6041 2.1 50570 18140 2 905.605319 453.8093 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3527.5 - 3.67E+06 - - - 1.3405 - 1.727 0.425 - 200.5 1 2 0 0.0012 8 0 0 0 1.37E+08 6.52E+07 - - - 3.8275 0.9923 230117_WJC_METTL3_WT_vs_EV_F06.18142.18142.2 0.176 12-Aug R.ALLFIPR.R "sp|P08238|HS90B_HUMAN,sp|O00585|CCL21_HUMAN,tr|Q5VZ73|Q5VZ73_HUMAN" 3 828.5222 2.06 50572 18142 2 828.522434 415.2684 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 9.79 3527.7 - 2.05E+06 - - - 0.3319 - 1.613 0.054 - 271.9 2 2 0 0.0003 7 0 0 0 6.37E+08 3.09E+08 - - - 0.8202 1 230117_WJC_METTL3_WT_vs_EV_F06.18146.18146.2 1.40E-08 16/30 R.IINEPTAAAIAYGLDK.R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1658.8879 29.54 50576 18146 2 1658.890663 830.4512 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3528.1 - 862696 - - - 1.6433 - 2.938 0.572 - 621.7 1 2 0 0.0027 16 0 0 0 2.97E+07 1.01E+06 - - - 5.9146 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18150.18150.2 0.00477 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 196.77 50579 18150 2 1006.57147 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3528.7 - 789514 - - - 1.5617 - 1.812 0.441 - 265.2 1 2 0 0.0016 9 0 0 0 8.06E+07 4.10E+05 - - - 4.0175 0.9718 230117_WJC_METTL3_WT_vs_EV_F06.18152.18152.2 9.5 12-Jul R.ALLFIPR[166.11].R "sp|P08238|HS90B_HUMAN,sp|O00585|CCL21_HUMAN,tr|Q5VZ73|Q5VZ73_HUMAN" 3 838.5304 2.06 50580 18152 2 838.531376 420.2725 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 9.79 3528.9 - 3.16E+06 - - - 1.1294 - 1.306 0.022 - 254.3 4 2 0 0.0009 7 0 0 0 6.37E+08 3.09E+08 - - - -0.2198 0.999 230117_WJC_METTL3_WT_vs_EV_F06.18154.18154.2 0.0145 18-Jul K.YLAIAPPIIK[136.11].Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1105.6991 1.88 50582 18154 2 1105.701824 553.8568 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3529.1 - 3.02E+06 - - - 2.4925 - 1.489 0.358 - 125.7 1 2 0 0.0028 10 0 0 0 1.98E+08 1.05E+08 - - - 2.7956 0.9853 230117_WJC_METTL3_WT_vs_EV_F06.18156.18156.2 0.171 12-Jun R.LVVLPFR[166.11].R sp|Q10570|CPSF1_HUMAN 1 852.5461 2.34 50584 18156 2 852.547542 427.2803 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 9.75 3529.4 - 678310 - - - 1.716 - 1.161 0.097 - 120.6 1 2 0 0.0015 7 0 0 0 3.63E+07 1.55E+07 - - - 0.23 0.992 230117_WJC_METTL3_WT_vs_EV_F06.18163.18163.2 0.00346 16-Oct R.LIDFLEC[160.03]GK[136.11].T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1101.562 0.92 50589 18163 2 1101.558053 551.7883 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3530.3 - 8.33E+06 - - - -3.5668 - 1.442 0.394 - 228.7 1 2 0 -0.0039 9 0 0 0 1.78E+08 1.93E+08 - - - 3.0088 0.9615 230117_WJC_METTL3_WT_vs_EV_F06.18164.18164.2 0.0243 16-Oct R.PLVETIFER[166.11].G "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 1112.6105 0.97 50590 18164 2 1112.610393 557.3125 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.53 3530.4 - 2.98E+06 - - - -0.1231 - 1.949 0.408 - 421.2 1 1 0 -0.0001 9 0 0 0 6.54E+07 6.74E+07 - - - 3.985 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18165.18165.2 0.000997 18-Aug R.VLITTDLLAR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 1123.684 1.53 50591 18165 2 1123.685855 562.8493 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3530.4 - 1.90E+06 - - - 1.6241 - 1.886 0.335 - 138.9 1 2 0 0.0018 10 0 0 0 3.79E+08 2.48E+08 - - - 3.2857 0.9603 230117_WJC_METTL3_WT_vs_EV_F06.18168.18168.2 0.00591 16-Jun K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 7.42 50594 18168 2 1014.539442 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3530.8 - 532637 - - - 4.7973 - 1.581 0.071 - 73.8 2 2 0 0.0049 9 0 0 0 1.75E+07 2.36E+06 - - - 0.7546 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.18170.18170.3 0.144 Oct-36 K.LAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1142.627 3.06 50596 18170 3 1142.628504 381.883 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3531 - 363635 - - - 1.2856 - 1.764 0.25 - 137.7 1 2 0 0.0015 10 0 0 0 6.02E+06 1.97E+06 - - - 2.9844 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18174.18174.2 0.000959 18-Jul R.VLITTDLLAR.G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 1113.6758 1.53 50598 18174 2 1113.677441 557.8452 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3531.6 - 1.16E+06 - - - 1.5094 - 1.694 0.427 - 189.1 1 2 0 0.0017 10 0 0 0 3.79E+08 2.48E+08 - - - 3.6656 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.18177.18177.2 0.0323 18-Jun K.FYALDPSFPR[166.11].M sp|Q08J23|NSUN2_HUMAN 1 1221.6058 1.8 50601 18177 2 1221.607438 611.8102 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3531.8 - 256499 - - - 1.358 - 1.319 0.3 - 115.6 1 2 0 0.0017 10 0 0 0 3.84E+07 2.14E+07 - - - 2.0291 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.18182.18182.2 0.014 14-Jul R.IGVMSLIR.K "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 887.5263 1.49 50604 18182 2 887.52624 444.7704 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 3532.4 - 920148 - - - -0.0214 - 1.597 0.304 - 132.1 1 2 0 0 8 0 0 0 5.34E+07 3.59E+07 - - - 2.6982 0.9155 230117_WJC_METTL3_WT_vs_EV_F06.18184.18184.2 0.00776 18-Sep N.MVVDAVLAIK.Y "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1057.6206 18.73 50606 18184 2 1057.622919 529.8176 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.59 3532.6 - 533210 - - - 2.2371 - 1.66 0.268 - 194.5 1 1 0 0.0024 10 0 0 0 2.08E+07 1.11E+06 - - - 2.4344 1 230117_WJC_METTL3_WT_vs_EV_F06.18190.18190.2 3.54E-06 18-Oct K.FYALDPSFPR.M sp|Q08J23|NSUN2_HUMAN 1 1211.5975 1.8 50609 18190 2 1211.601408 606.806 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3533.4 - 777751 - - - 3.2181 - 2.123 0.582 - 329.9 1 2 0 0.0039 10 0 0 0 3.84E+07 2.14E+07 - - - 5.4398 0.9937 230117_WJC_METTL3_WT_vs_EV_F06.18197.18197.2 0.0222 14-Jul R.FLFPEGIK[136.11].G "sp|O75891|AL1L1_HUMAN,sp|Q3SY69|AL1L2_HUMAN,tr|C9IZ36|C9IZ36_HUMAN,tr|A0A494C1M4|A0A494C1M4_HUMAN" 4 957.5415 1.28 50616 18197 2 957.540009 479.778 Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L1 PE=1 SV=2 6 3534.2 - 189454 - - - -1.5613 - 1.247 0.298 - 114.1 1 2 0 -0.0015 8 0 0 0 1.29E+07 1.00E+07 - - - 1.9073 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.18200.18200.2 0.357 14-Jul R.IGVMSLIR[166.11].K "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 897.5345 1.49 50617 18200 2 897.535794 449.7745 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 3534.6 - 3.06E+06 - - - 1.4094 - 1.488 0.184 - 139.3 1 2 0 0.0013 8 0 0 0 5.34E+07 3.59E+07 - - - 1.5983 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.18201.18201.2 3.79E-05 20-Nov K.LDPGLIMEQVK.V sp|Q9Y5L4|TIM13_HUMAN 1 1241.669 2.34 50618 18201 2 1241.674736 621.8418 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3534.7 - 724939 - - - 4.6518 - 2 0.456 - 415.5 1 2 0 0.0058 11 0 0 0 1.88E+07 8.02E+06 - - - 4.2823 1 230117_WJC_METTL3_WT_vs_EV_F06.18202.18202.2 6.19E-05 13/22 R.APVVAIAVLDGR[166.11].G "sp|Q15334|L2GL1_HUMAN,tr|A0A087WW77|A0A087WW77_HUMAN" 2 1189.7058 1.72 50619 18202 2 1189.702331 595.8602 Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens OX=9606 GN=LLGL1 PE=1 SV=3 5.88 3534.8 - 473982 - - - -2.9394 - 2.94 0.538 - 674.8 1 2 0 -0.0035 12 0 0 0 1.18E+07 6.84E+06 - - - 5.851 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.18203.18203.2 2.29E-05 26-Dec K.IIVPNSTAGLIIGK.G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VW64|F8VW64_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|M0R1A0|M0R1A0_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|G8JLA5|G8JLA5_HUMAN" 8 1394.8497 2.39 50620 18203 2 1394.856391 698.4321 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.75 3535 - 331533 - - - 4.7962 - 1.849 0.499 - 276.5 1 2 0 0.0067 14 0 0 0 3.38E+06 1.41E+06 - - - 4.2669 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18205.18205.2 0.0106 28-Sep R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 9.88 50622 18205 2 1484.910892 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3535.2 - 157805 - - - 2.025 - 1.967 0.378 - 125.2 1 2 0 0.003 15 0 0 0 9.16E+06 9.28E+05 - - - 3.4952 0.9629 230117_WJC_METTL3_WT_vs_EV_F06.18209.18209.2 0.011 16-Aug N.LLLNYGLYR[166.11].K "sp|Q92769|HDAC2_HUMAN,sp|Q13547|HDAC1_HUMAN,tr|E5RHE7|E5RHE7_HUMAN,tr|E5RGV4|E5RGV4_HUMAN,tr|H3BM24|H3BM24_HUMAN,tr|E5RJ04|E5RJ04_HUMAN,tr|E5RG37|E5RG37_HUMAN,tr|E5RH52|E5RH52_HUMAN,tr|E5RK19|E5RK19_HUMAN,tr|E5RFP9|E5RFP9_HUMAN,tr|E5RFI6|E5RFI6_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 12 1133.6472 1.35 50624 18209 2 1133.648561 567.8309 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 8.59 3535.7 - 1.27E+06 - - - 1.1564 - 1.866 0.329 - 175.6 1 1 0 0.0013 9 0 0 0 1.92E+07 1.42E+07 - - - 3.2753 0.9699 230117_WJC_METTL3_WT_vs_EV_F06.18210.18210.2 0.000143 22-Oct R.APVVAIAVLDGR.G "sp|Q15334|L2GL1_HUMAN,tr|A0A087WW77|A0A087WW77_HUMAN" 2 1179.6976 1.72 50625 18210 2 1179.689259 590.8561 Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens OX=9606 GN=LLGL1 PE=1 SV=3 5.88 3535.8 - 1.77E+06 - - - -7.0349 - 2.436 0.406 - 331.2 1 2 0 -0.0083 12 0 0 0 1.18E+07 6.84E+06 - - - 4.3798 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.18211.18211.2 0.336 18-Jul R.ILELDQELIK[136.11].A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1220.7108 1.33 50626 18211 2 1220.713498 611.3627 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3535.9 - 1.83E+06 - - - 2.2471 - 1.678 0.204 - 97.7 1 2 0 0.0027 10 0 0 0 4.62E+07 3.48E+07 - - - 1.9917 0.999 230117_WJC_METTL3_WT_vs_EV_F06.18212.18212.2 0.0344 18-Oct R.ILELDQELIK.A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1212.6966 1.32 50627 18212 2 1212.698852 607.3556 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3535.9 - 1.77E+06 - - - 1.8941 - 1.76 0.254 - 255 1 2 0 0.0023 10 0 0 0 4.62E+07 3.49E+07 - - - 2.4943 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.18214.18214.2 0.0769 20-Jul R.LGIPDAVSYIK.K sp|O94874|UFL1_HUMAN 1 1174.6598 2.06 50629 18214 2 1174.661016 588.3372 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.83 3536 - 764051 - - - 1.0565 - 1.441 0.254 - 76.1 1 2 0 0.0012 11 0 0 0 2.87E+07 1.39E+07 - - - 1.905 0.9901 230117_WJC_METTL3_WT_vs_EV_F06.18215.18215.2 0.34 20-Aug K.NLIDAGVDALR[166.11].V "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1165.6331 1.26 50630 18215 2 1165.629574 583.8238 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.21 3536.2 - 620383 - - - -2.9881 - 1.766 0.239 - 140.1 1 2 0 -0.0035 11 0 0 0 6.20E+06 4.91E+06 - - - 2.3437 0.9633 230117_WJC_METTL3_WT_vs_EV_F06.18223.18223.2 0.126 13/16 K.TLGILGLGR.L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 898.56 2.08 50636 18223 2 898.566031 450.2873 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3537.1 - 2.17E+06 - - - 6.7096 - 1.888 0.131 - 584.4 1 2 0 0.006 9 0 0 0 4.64E+08 2.23E+08 - - - 1.8453 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.18224.18224.2 0.0228 16-Aug R.YYIDADLLR[166.11].E sp|Q7Z3B4|NUP54_HUMAN 1 1150.5898 2.71 50637 18224 2 1150.593886 576.3022 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.21 3537.2 - 2.11E+06 - - - 3.5556 - 1.627 0.257 - 191.7 1 2 0 0.0041 9 0 0 0 8.71E+07 3.21E+07 - - - 2.3461 1 230117_WJC_METTL3_WT_vs_EV_F06.18225.18225.2 0.000192 13/20 R.VVGVLLGSWQK.K "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 1184.6917 1.49 50638 18225 2 1184.701221 593.3531 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 8.72 3537.3 - 1.04E+06 - - - 7.9995 - 2.325 0.508 - 595.1 1 2 0 0.0095 11 0 0 0 2.77E+07 1.86E+07 - - - 5.0726 1 230117_WJC_METTL3_WT_vs_EV_F06.18226.18226.2 0.0241 22-Nov K.IPGIIIAASAVR.A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1179.7339 2.22 50639 18226 2 1179.737449 590.8742 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3537.5 - 898495 - - - 2.9719 - 2.404 0.486 - 411.4 1 2 0 0.0035 12 0 0 0 3.69E+07 1.66E+07 - - - 4.9374 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18227.18227.2 0.000377 20-Nov K.LDPGLIMEQVK[136.11].V sp|Q9Y5L4|TIM13_HUMAN 1 1249.6832 2.34 50640 18227 2 1249.685447 625.8489 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3537.6 - 474121 - - - 1.8301 - 1.971 0.394 - 454.1 1 2 0 0.0023 11 0 0 0 1.88E+07 8.02E+06 - - - 3.786 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18229.18229.2 0.000809 26-Oct K.VLIPSYAAGSIIGK.G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|F8W659|F8W659_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|F8VYI3|F8VYI3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|I3L2B5|I3L2B5_HUMAN" 8 1387.8075 2.75 50642 18229 2 1387.809684 694.911 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.56 3537.8 - 385447 - - - 1.5723 - 1.86 0.445 - 118.9 1 2 0 0.0022 14 0 0 0 9.68E+06 3.52E+06 - - - 3.8844 1 230117_WJC_METTL3_WT_vs_EV_F06.18236.18236.2 9.06E-06 13/22 R.FLAVGLVDNTVR[166.11].L sp|Q15393|SF3B3_HUMAN 1 1312.7379 1.1 50647 18236 2 1312.739962 657.3762 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3538.7 - 8.42E+06 - - - 1.6043 - 2.432 0.545 - 626.4 1 2 0 0.0021 12 0 0 0 1.61E+08 1.46E+08 - - - 5.4041 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18237.18237.2 0.000171 16-Sep R.YYIDADLLR.E sp|Q7Z3B4|NUP54_HUMAN 1 1140.5815 2.71 50648 18237 2 1140.583577 571.298 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.21 3538.8 - 6.43E+06 - - - 1.7991 - 1.745 0.466 - 273.2 1 2 0 0.0021 9 0 0 0 8.72E+07 3.21E+07 - - - 4.093 0.9892 230117_WJC_METTL3_WT_vs_EV_F06.18240.18240.2 0.0189 20-Dec K.LALDMEISAYR.K "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN" 2 1280.6435 1.64 50651 18240 2 1280.652971 641.329 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.37 3539.2 - 420705 - - - 7.4166 - 2.272 0.358 - 679.8 1 2 0 0.0095 11 0 0 0 6.47E+06 3.94E+06 - - - 3.9023 0.9701 230117_WJC_METTL3_WT_vs_EV_F06.18242.18242.2 0.000667 26-Sep K.VLIPSYAAGSIIGK[136.11].G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|F8W659|F8W659_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|F8VYI3|F8VYI3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|I3L2B5|I3L2B5_HUMAN" 8 1395.8217 2.8 50653 18242 2 1395.815014 698.9181 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.56 3539.4 - 193599 - - - -4.7914 - 1.803 0.247 - 177.3 1 2 0 -0.0067 14 0 0 0 9.54E+06 3.41E+06 - - - 2.3424 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18246.18246.2 0.00309 22-Aug R.FLAVGLVDNTVR.L sp|Q15393|SF3B3_HUMAN 1 1302.7296 1.1 50656 18246 2 1302.732695 652.3721 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3539.9 - 1.36E+07 - - - 2.3865 - 1.877 0.405 - 229.8 1 2 0 0.0031 12 0 0 0 1.61E+08 1.46E+08 - - - 3.6881 0.9921 230117_WJC_METTL3_WT_vs_EV_F06.18249.18249.2 0.603 20-Aug K.LVAASQAALGL.- "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 1012.5917 - 50658 18249 2 1012.591409 507.3031 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.52 3540.2 - 718059 - - - -0.2834 - 1.529 0.116 - 80.8 1 2 0 -0.0003 11 0 0 0 - - - - - 1.0464 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.18255.18255.2 1.14 12-Aug K.ILVDLLK.L "sp|Q6P582|MZT2A_HUMAN,sp|Q6NZ67|MZT2B_HUMAN,tr|H7C202|H7C202_HUMAN,tr|B8ZZ87|B8ZZ87_HUMAN,tr|A0A494C0V9|A0A494C0V9_HUMAN,tr|H7BZ50|H7BZ50_HUMAN,tr|H7C173|H7C173_HUMAN" 7 812.5371 2 50664 18255 2 812.538385 407.2758 Mitotic-spindle organizing protein 2A OS=Homo sapiens OX=9606 GN=MZT2A PE=1 SV=2 5.84 3540.9 - 323120 - - - 1.531 - 1.846 0.201 - 161.9 1 2 0 0.0012 7 0 0 0 1.35E+07 6.78E+06 - - - 2.4676 0.9947 230117_WJC_METTL3_WT_vs_EV_F06.18259.18259.2 22.9 16-Oct K.TLGILGLGR[166.11].L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 908.5683 2.08 50667 18259 2 908.569741 455.2914 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3541.4 - 1.31E+07 - - - 1.6168 - 1.422 0.12 - 331.2 1 2 0 0.0015 9 0 0 0 4.64E+08 2.23E+08 - - - 0.9454 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.18261.18261.2 0.753 14-Aug R.SSLLLGFR.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 891.5178 0.92 50668 18261 2 891.521499 446.7662 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 9.47 3541.6 - 3.56E+06 - - - 4.1469 - 1.724 0.236 - 228.3 1 2 0 0.0037 8 0 0 0 6.58E+07 7.15E+07 - - - 2.4256 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18265.18265.2 0.000564 22-Dec K.LIVDPALDPALR.R "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN,tr|C9J2Z9|C9J2Z9_HUMAN" 3 1291.75 2.48 50672 18265 2 1291.751361 646.8823 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.21 3542.1 - 417875 - - - 1.0637 - 2.135 0.463 - 446 1 2 0 0.0014 12 0 0 0 3.31E+07 1.33E+07 - - - 4.4559 0.9711 230117_WJC_METTL3_WT_vs_EV_F06.18266.18266.2 0.261 12-Jun K.AFFSPFR.L sp|Q92626|PXDN_HUMAN 1 870.4388 1.02 50673 18266 2 870.440938 436.2267 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 9.79 3542.2 - 412378 - - - 2.4287 - 1.26 0.023 - 131.5 1 2 0 0.0021 7 0 0 0 7.30E+06 7.18E+06 - - - -0.0575 1 230117_WJC_METTL3_WT_vs_EV_F06.18268.18268.2 2.03E-05 28-Nov R.LGALQGDPEALTLYR.E sp|Q9P253|VPS18_HUMAN 1 1615.857 11.59 50675 18268 2 1615.859832 808.9358 Vacuolar protein sorting-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=VPS18 PE=1 SV=2 4.37 3542.4 - 263370 - - - 1.77 - 2.352 0.539 - 288.6 1 2 0 0.0029 15 0 0 0 2.16E+06 1.86E+05 - - - 5.1239 0.9897 230117_WJC_METTL3_WT_vs_EV_F06.18269.18269.2 0.0639 20-Jul R.VFEFGGPEVLK[136.11].L "sp|Q08257|QOR_HUMAN,tr|C9JH92|C9JH92_HUMAN,tr|A6NP24|A6NP24_HUMAN" 3 1228.6583 1.44 50676 18269 2 1228.663869 615.3364 Quinone oxidoreductase OS=Homo sapiens OX=9606 GN=CRYZ PE=1 SV=1 4.53 3542.6 - 221693 - - - 4.5122 - 1.411 0.232 - 101.2 1 2 0 0.0055 11 0 0 0 6.33E+06 4.40E+06 - - - 1.6842 0.977 230117_WJC_METTL3_WT_vs_EV_F06.18271.18271.2 1.42 28-May R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 10.21 50678 18271 2 1494.918579 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3542.8 - 66689.5 - - - 1.6215 - 1.137 0.113 - 53.2 4 2 0 0.0024 15 0 0 0 9.47E+06 9.28E+05 - - - -0.0784 0.9378 230117_WJC_METTL3_WT_vs_EV_F06.18275.18275.2 0.726 12-Jun K.MIADFLR.E "sp|Q96R72|OR4K3_HUMAN,sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 4 864.4528 7.15 50681 18275 2 864.458498 433.2337 Olfactory receptor 4K3 OS=Homo sapiens OX=9606 GN=OR4K3 PE=3 SV=3 5.59 3543.3 - 1.22E+06 - - - 6.6389 - 1.344 0.184 - 167.1 1 2 0 0.0057 7 0 0 0 1.19E+08 1.66E+07 - - - 1.335 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18276.18276.2 0.00042 14-Sep K.LWGVIDVK.R "sp|Q9UHD1|CHRD1_HUMAN,tr|E9PHZ2|E9PHZ2_HUMAN" 2 928.5382 3.51 50682 18276 2 928.540005 465.2764 Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2 5.84 3543.4 - 812027 - - - 1.9407 - 1.753 0.39 - 240.4 1 2 0 0.0018 8 0 0 0 2.25E+07 6.42E+06 - - - 3.6139 1 230117_WJC_METTL3_WT_vs_EV_F06.18282.18282.2 0.0145 13/22 K.IPGIIIAASAVR[166.11].A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1189.7422 2.27 50686 18282 2 1189.74675 595.8784 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3544 - 1.33E+06 - - - 3.8134 - 2.555 0.502 - 611.7 1 2 0 0.0045 12 0 0 0 4.26E+07 1.88E+07 - - - 5.2155 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.18283.18283.2 18.9 12-Jul K.MIADFLR[166.11].E "sp|Q96R72|OR4K3_HUMAN,sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 4 874.461 7.41 50687 18283 2 874.46284 438.2378 Olfactory receptor 4K3 OS=Homo sapiens OX=9606 GN=OR4K3 PE=3 SV=3 5.59 3544.1 - 904957 - - - 2.071 - 1.394 0.177 - 199.9 1 2 0 0.0018 7 0 0 0 1.19E+08 1.60E+07 - - - 1.4003 0.9392 230117_WJC_METTL3_WT_vs_EV_F06.18285.18285.2 0.237 14-Jul K.IGGIFAFK.V "sp|P22307|SCP2_HUMAN,tr|H0YF61|H0YF61_HUMAN" 2 851.4905 1.72 50689 18285 2 851.487291 426.7525 Sterol carrier protein 2 OS=Homo sapiens OX=9606 GN=SCP2 PE=1 SV=2 8.75 3544.4 - 340367 - - - -3.798 - 1.367 0.156 - 91.3 1 2 0 -0.0032 8 0 0 0 5.69E+06 3.32E+06 - - - 1.135 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.18291.18291.2 0.000521 16-Sep K.GIFLGDQWR.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1090.556 2.63 50693 18291 2 1090.561274 546.2853 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3545.2 - 9.42E+06 - - - 4.8553 - 1.615 0.423 - 305.6 1 2 0 0.0053 9 0 0 0 1.52E+08 5.79E+07 - - - 3.5504 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.18294.18294.2 0.000622 18-Aug R.YLYTLVITDK.E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1227.6751 1.42 50696 18294 2 1227.677916 614.8448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3545.4 - 1.73E+06 - - - 2.3011 - 1.729 0.289 - 164.1 1 2 0 0.0028 10 0 0 0 9.61E+08 6.76E+08 - - - 2.703 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18295.18295.2 0.00345 18-Oct R.YLYTLVITDK[136.11].E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1235.6893 1.42 50697 18295 2 1235.692572 618.8519 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3545.5 - 1.67E+06 - - - 2.6552 - 1.98 0.352 - 263.3 1 2 0 0.0033 10 0 0 0 9.61E+08 6.77E+08 - - - 3.5466 0.9671 230117_WJC_METTL3_WT_vs_EV_F06.18296.18296.2 0.0091 20-Nov R.LLDLVVQPVPR.P sp|Q8WYP5|ELYS_HUMAN 1 1247.7602 1.4 50698 18296 2 1247.763175 624.8874 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.84 3545.6 - 974296 - - - 2.4179 - 2.123 0.389 - 449.8 1 1 0 0.003 11 0 0 0 1.46E+07 1.04E+07 - - - 3.9498 0.9738 230117_WJC_METTL3_WT_vs_EV_F06.18297.18297.2 0.00848 22-Dec H.IISELILTAQER.D sp|Q96I24|FUBP3_HUMAN 1 1384.7926 1.5 50699 18297 2 1384.795382 693.4036 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3545.7 - 894706 - - - 2.0234 - 2.386 0.375 - 363.3 1 1 0 0.0028 12 0 0 0 9.89E+06 6.58E+06 - - - 4.098 0.9747 230117_WJC_METTL3_WT_vs_EV_F06.18298.18298.2 0.00574 13/22 H.IISELILTAQER[166.11].D sp|Q96I24|FUBP3_HUMAN 1 1394.8009 1.5 50700 18298 2 1394.80376 698.4077 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3545.8 - 820377 - - - 2.0863 - 2.505 0.377 - 652.8 1 1 0 0.0029 12 0 0 0 9.89E+06 6.58E+06 - - - 4.2408 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.18299.18299.2 0.76 12-Jul R.YDLWNLK[136.11].Y sp|Q9ULW3|ABT1_HUMAN 1 958.5004 0.75 50701 18299 2 958.502585 480.2575 Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1 5.83 3545.9 - 718698 - - - 2.313 - 1.465 0.256 - 157.5 1 2 0 0.0022 7 0 0 0 1.38E+07 1.84E+07 - - - 2.141 0.9591 230117_WJC_METTL3_WT_vs_EV_F06.18300.18300.2 0.000686 20-Nov R.LLDLVVQPVPR[166.11].P sp|Q8WYP5|ELYS_HUMAN 1 1257.7684 1.4 50702 18300 2 1257.771791 629.8915 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.84 3546.1 - 717389 - - - 2.6738 - 2.248 0.345 - 473 1 1 0 0.0034 11 0 0 0 1.46E+07 1.04E+07 - - - 3.7795 0.9236 230117_WJC_METTL3_WT_vs_EV_F06.18303.18303.2 0.149 22-Nov L.PLIPIVVEQTGR.G sp|Q16740|CLPP_HUMAN 1 1320.7765 1.73 50705 18303 2 1320.780346 661.3955 "ATP-dependent Clp protease proteolytic subunit, mitochondrial OS=Homo sapiens OX=9606 GN=CLPP PE=1 SV=1" 6.43 3546.5 - 473049 - - - 2.8847 - 1.863 0.309 - 259.1 1 1 0 0.0038 12 0 0 0 1.13E+07 6.53E+06 - - - 2.9592 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18306.18306.2 0.000883 18-Aug K.LWTMPISSVR[166.11].F "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1198.6408 2.03 50708 18306 2 1198.642477 600.3277 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3546.9 - 372483 - - - 1.4116 - 1.914 0.297 - 195.5 1 2 0 0.0017 10 0 0 0 9.59E+06 4.73E+06 - - - 3.0462 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.18312.18312.2 0.0043 16-Aug K.GIFLGDQWR[166.11].D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1100.5642 2.62 50713 18312 2 1100.565582 551.2894 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3547.4 - 6.94E+06 - - - 1.2112 - 1.517 0.219 - 193.1 1 2 0 0.0013 9 0 0 0 1.51E+08 5.79E+07 - - - 1.8638 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18318.18318.2 0.000564 16-Aug K.YMAEALLLR.A sp|O94826|TOM70_HUMAN 1 1078.5845 1.19 50719 18318 2 1078.587624 540.2995 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 6 3547.7 - 1.47E+06 - - - 2.8945 - 2.007 0.454 - 198.9 1 2 0 0.0031 9 0 0 0 1.11E+07 9.30E+06 - - - 4.4087 0.9915 230117_WJC_METTL3_WT_vs_EV_F06.18319.18319.2 2.82 12-Jun R.YDLWNLK.Y sp|Q9ULW3|ABT1_HUMAN 1 950.4862 0.76 50720 18319 2 950.487278 476.2504 Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1 5.83 3547.8 - 1.31E+06 - - - 1.1678 - 1.231 0.121 - 103 1 2 0 0.0011 7 0 0 0 1.38E+07 1.83E+07 - - - 0.5929 0.9779 230117_WJC_METTL3_WT_vs_EV_F06.18321.18321.2 3.78 16-Jul R.LALILC[160.03]VTK.A sp|P31944|CASPE_HUMAN 1 1029.6256 6.47 50722 18321 2 1029.625799 515.8201 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 8.22 3548 - 585462 - - - 0.1554 - 1.372 0.067 - 48.8 5 2 0 0.0002 9 0 0 0 6.44E+06 9.96E+05 - - - 0.1386 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18322.18322.2 0.00284 20-Aug K.VMVTNVTSLLK.T "sp|Q9Y4G6|TLN2_HUMAN,sp|Q9Y490|TLN1_HUMAN,tr|A0A1B0GVU7|A0A1B0GVU7_HUMAN,tr|H0YMT1|H0YMT1_HUMAN" 4 1203.6897 0.38 50723 18322 2 1203.691621 602.8521 Talin-2 OS=Homo sapiens OX=9606 GN=TLN2 PE=1 SV=4 8.72 3548.1 - 456307 - - - 1.6001 - 1.535 0.377 - 119 1 2 0 0.0019 11 0 0 0 7.51E+06 1.99E+07 - - - 2.9842 1 230117_WJC_METTL3_WT_vs_EV_F06.18326.18326.2 9.22E-09 26-Dec K.FYGPEGPYGVFAGR[166.11].D sp|O00264|PGRC1_HUMAN 1 1525.7229 1.4 50727 18326 2 1525.726907 763.8687 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3548.6 - 197610 - - - 2.604 - 2.203 0.603 - 331.5 1 2 0 0.004 14 0 0 0 3.14E+07 2.24E+07 - - - 5.4755 0.9931 230117_WJC_METTL3_WT_vs_EV_F06.18331.18331.2 0.0525 20-Aug R.ILDVGFEEELK[136.11].Q "sp|Q9NVP1|DDX18_HUMAN,tr|H7C452|H7C452_HUMAN" 2 1298.6849 1.46 50730 18331 2 1298.69124 650.3497 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 4 3549.1 - 1.86E+06 - - - 4.8557 - 1.601 0.268 - 172.7 1 2 0 0.0063 11 0 0 0 1.77E+07 1.21E+07 - - - 2.2916 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.18332.18332.2 0.0851 12-Apr K.FALPYIR.D "sp|P06132|DCUP_HUMAN,tr|Q5T446|Q5T446_HUMAN,tr|A0A1B0GVN9|A0A1B0GVN9_HUMAN,tr|H0Y5R6|H0Y5R6_HUMAN,tr|A0A494C0S8|A0A494C0S8_HUMAN,tr|A0A494C0Q8|A0A494C0Q8_HUMAN,tr|A0A494C085|A0A494C085_HUMAN" 7 878.5014 1.53 50731 18332 2 878.50241 440.258 Uroporphyrinogen decarboxylase OS=Homo sapiens OX=9606 GN=UROD PE=1 SV=2 8.75 3549.2 - 1.77E+06 - - - 1.1224 - 1.064 0.364 - 59.6 1 2 0 0.001 7 0 0 0 2.51E+07 1.64E+07 - - - 1.9258 1 230117_WJC_METTL3_WT_vs_EV_F06.18333.18333.2 1.07E-05 13/22 K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 126.47 50732 18333 2 1382.681635 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3549.2 - 1.23E+06 - - - -1.0089 - 2.48 0.512 - 491.3 1 2 0 -0.0014 12 0 0 0 2.58E+07 2.04E+05 - - - 5.212 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18337.18337.2 0.00177 18-Nov K.IGSDVELLLR.T sp|Q5U5X0|LYRM7_HUMAN 1 1113.6394 2.13 50734 18337 2 1113.641569 557.827 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 4.37 3549.7 - 818249 - - - 1.971 - 2.336 0.389 - 263.9 1 2 0 0.0022 10 0 0 0 4.05E+07 1.90E+07 - - - 4.2817 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.18338.18338.2 0.000492 20-Jul K.FGEPVLAGFAR[166.11].S sp|O15067|PUR4_HUMAN 1 1172.6218 4.26 50735 18338 2 1172.62526 587.3182 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 6 3549.8 - 1.00E+06 - - - 2.9814 - 1.781 0.348 - 174 1 2 0 0.0035 11 0 0 0 5.26E+07 1.24E+07 - - - 3.1716 1 230117_WJC_METTL3_WT_vs_EV_F06.18339.18339.2 6.90E-12 14/26 K.FYGPEGPYGVFAGR.D sp|O00264|PGRC1_HUMAN 1 1515.7147 1.4 50736 18339 2 1515.716599 758.8646 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3549.9 - 797486 - - - 1.2766 - 2.596 0.705 - 656.9 1 2 0 0.0019 14 0 0 0 3.14E+07 2.24E+07 - - - 6.6415 0.999 230117_WJC_METTL3_WT_vs_EV_F06.18345.18345.2 0.0023 14-Sep R.GFGFVQFK[136.11].N "sp|Q9NW13|RBM28_HUMAN,tr|C9JE21|C9JE21_HUMAN" 2 936.4949 0.8 50740 18345 2 936.49622 469.2547 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 8.75 3550.6 - 587299 - - - 1.4213 - 1.569 0.276 - 242.3 1 2 0 0.0013 8 0 0 0 1.55E+07 1.95E+07 - - - 2.4376 0.9646 230117_WJC_METTL3_WT_vs_EV_F06.18349.18349.2 1.23 18-Jul K.LWTMPISSVR.F "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1188.6325 1.66 50744 18349 2 1188.636819 595.3235 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3551 - 313873 - - - 3.621 - 1.24 0.086 - 126.5 1 2 0 0.0043 10 0 0 0 9.71E+06 5.85E+06 - - - 0.2753 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18354.18354.2 0.000132 16-Oct R.ILFLDPSGK.V sp|O95881|TXD12_HUMAN 1 988.5593 1.13 50747 18354 2 988.561682 495.2869 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3551.6 - 2.78E+06 - - - 2.3762 - 1.894 0.441 - 258.1 1 2 0 0.0023 9 0 0 0 4.42E+08 3.92E+08 - - - 4.1453 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.18355.18355.2 0.209 16-Jun R.ILFLDPSGK[136.11].V sp|O95881|TXD12_HUMAN 1 996.5735 1.13 50748 18355 2 996.574802 499.294 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3551.7 - 3.32E+06 - - - 1.2734 - 1.411 0.266 - 76.9 1 2 0 0.0013 9 0 0 0 4.42E+08 3.92E+08 - - - 2.0014 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18356.18356.2 0.00155 18-Sep K.GLVASLISVK.D sp|O95347|SMC2_HUMAN 1 985.6172 1.18 50749 18356 2 985.618633 493.8159 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 8.75 3551.7 - 3.21E+06 - - - 1.4722 - 2.053 0.441 - 242.1 1 2 0 0.0015 10 0 0 0 3.59E+07 3.03E+07 - - - 4.3056 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.18358.18358.2 0.00857 18-Oct K.GLVASLISVK[136.11].D sp|O95347|SMC2_HUMAN 1 993.6314 1.18 50751 18358 2 993.63253 497.823 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 8.75 3551.9 - 3.11E+06 - - - 1.1554 - 2.425 0.154 - 368 1 2 0 0.0011 10 0 0 0 3.59E+07 3.03E+07 - - - 2.6507 1 230117_WJC_METTL3_WT_vs_EV_F06.18361.18361.2 5.28E-05 22-Nov K.IVAISC[160.03]AADILK.A "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|F6XAQ5|F6XAQ5_HUMAN" 4 1272.7112 1.5 50754 18361 2 1272.712492 637.3629 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.83 3552.2 - 775091 - - - 1.0474 - 2.095 0.496 - 332 1 2 0 0.0013 12 0 0 0 6.43E+06 4.29E+06 - - - 4.6499 0.9757 230117_WJC_METTL3_WT_vs_EV_F06.18367.18367.2 0.884 14-May R.GFGFVQFK.N "sp|Q9NW13|RBM28_HUMAN,tr|C9JE21|C9JE21_HUMAN" 2 928.4807 0.79 50758 18367 2 928.4815 465.2476 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 8.75 3552.8 - 1.70E+06 - - - 0.8735 - 0.913 0.154 - 65.4 1 2 0 0.0008 8 0 0 0 1.55E+07 1.95E+07 - - - -0.0963 1 230117_WJC_METTL3_WT_vs_EV_F06.18368.18368.2 0.00205 18-Oct K.IGSDVELLLR[166.11].T sp|Q5U5X0|LYRM7_HUMAN 1 1123.6476 2.13 50759 18368 2 1123.646549 562.8311 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 4.37 3552.9 - 1.31E+06 - - - -0.9745 - 2.429 0.461 - 229.8 1 2 0 -0.0011 10 0 0 0 4.05E+07 1.90E+07 - - - 4.9228 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18371.18371.2 0.00042 20-Oct R.MLDMGFEPQIR[166.11].R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1345.6398 1.18 50762 18371 2 1345.642315 673.8272 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3553.2 - 552415 - - - 1.8705 - 2.12 0.459 - 402 1 2 0 0.0025 11 0 0 0 5.18E+07 4.40E+07 - - - 4.4631 1 230117_WJC_METTL3_WT_vs_EV_F06.18375.18375.2 7.29E-05 20-Oct R.MLDMGFEPQIR.R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1335.6315 1.18 50764 18375 2 1335.632809 668.823 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3553.8 - 1.50E+06 - - - 0.9591 - 2.137 0.527 - 408.2 1 2 0 0.0013 11 0 0 0 5.18E+07 4.40E+07 - - - 4.9874 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.18376.18376.2 0.155 14-Aug R.EMVLEIIR[166.11].E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1011.5662 1.29 50765 18376 2 1011.567787 506.7904 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3553.9 - 3.70E+06 - - - 1.5461 - 1.696 0.212 - 326.8 1 2 0 0.0016 8 0 0 0 1.43E+08 1.10E+08 - - - 2.1996 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.18379.18379.2 0.0972 16-Sep K.ILLITEDLK.N sp|Q08752|PPID_HUMAN 1 1056.6431 3.02 50768 18379 2 1056.645325 529.3288 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 4.37 3554.2 - 1.23E+06 - - - 2.1407 - 1.866 0.172 - 215.2 1 2 0 0.0023 9 0 0 0 1.28E+07 4.24E+06 - - - 2.1154 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18382.18382.2 0.0451 16-Aug K.LEVDIPLVK.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1024.6168 4.23 50771 18382 2 1024.618815 513.3157 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3554.6 - 851668 - - - 1.9197 - 1.672 0.408 - 170.8 1 2 0 0.002 9 0 0 0 7.78E+07 1.84E+07 - - - 3.541 0.8497 230117_WJC_METTL3_WT_vs_EV_F06.18383.18383.2 0.864 18-Jun R.VIALGLPVPR.Y sp|A3KMH1|VWA8_HUMAN 1 1033.6648 1.56 50772 18383 2 1033.669689 517.8397 von Willebrand factor A domain-containing protein 8 OS=Homo sapiens OX=9606 GN=VWA8 PE=1 SV=2 9.72 3554.8 - 850064 - - - 4.7288 - 1.204 0.093 - 46.2 13 2 0 0.0049 10 0 0 0 2.96E+06 1.90E+06 - - - -0.253 0.9762 230117_WJC_METTL3_WT_vs_EV_F06.18386.18386.2 2.59 18-Jun R.VIALGLPVPR[166.11].Y sp|A3KMH1|VWA8_HUMAN 1 1043.6731 1.56 50775 18386 2 1043.674381 522.8438 von Willebrand factor A domain-containing protein 8 OS=Homo sapiens OX=9606 GN=VWA8 PE=1 SV=2 9.72 3555.1 - 481185 - - - 1.2552 - 1.218 0.091 - 63.1 7 2 0 0.0013 10 0 0 0 2.96E+06 1.90E+06 - - - -0.1143 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.18393.18393.2 0.56 14-Jul R.EMVLEIIR.E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1001.558 1.29 50781 18393 2 1001.558995 501.7863 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3555.9 - 8.86E+06 - - - 1.0404 - 1.641 0.169 - 309.5 1 2 0 0.001 8 0 0 0 1.42E+08 1.10E+08 - - - 1.7827 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.18394.18394.2 0.0715 14-Aug K.VALLLLEK.E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 897.5899 1.18 50782 18394 2 897.590854 449.8022 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3556 - 1.53E+06 - - - 1.0573 - 1.698 0.253 - 209.9 1 2 0 0.0009 8 0 0 0 1.39E+07 1.18E+07 - - - 2.5062 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18396.18396.2 0.00379 22-Oct K.GLTPSQIGVILR[166.11].D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1262.7586 0.88 50784 18396 2 1262.760899 632.3866 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3556.1 - 1.12E+06 - - - 1.827 - 2.328 0.343 - 413.1 1 2 0 0.0023 12 0 0 0 2.46E+07 2.79E+07 - - - 3.797 1 230117_WJC_METTL3_WT_vs_EV_F06.18397.18397.2 2.11E-06 16-Nov K.LYMVLITTK.N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 3 1080.6253 1.57 50785 18397 2 1080.627208 541.3199 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 8.59 3556.2 - 1.03E+06 - - - 1.7619 - 2.024 0.552 - 412.8 1 2 0 0.0019 9 0 0 0 7.87E+06 5.01E+06 - - - 5.1573 0.9942 230117_WJC_METTL3_WT_vs_EV_F06.18399.18399.2 0.0562 16-Jul R.LLYGMALVR.F "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3R6|A0A7I2V3R6_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V4V0|A0A7I2V4V0_HUMAN,tr|A0A7I2V5R7|A0A7I2V5R7_HUMAN,tr|A0A7I2V653|A0A7I2V653_HUMAN,tr|A0A7I2YQI7|A0A7I2YQI7_HUMAN" 7 1034.5947 1.37 50787 18399 2 1034.598649 518.3046 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 8.75 3556.4 - 652279 - - - 3.8431 - 1.45 0.226 - 87.4 1 2 0 0.004 9 0 0 0 6.18E+06 4.52E+06 - - - 1.7839 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.18400.18400.2 0.119 16-Jul R.LLYGMALVR[166.11].F "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3R6|A0A7I2V3R6_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V4V0|A0A7I2V4V0_HUMAN,tr|A0A7I2V5R7|A0A7I2V5R7_HUMAN,tr|A0A7I2V653|A0A7I2V653_HUMAN,tr|A0A7I2YQI7|A0A7I2YQI7_HUMAN" 7 1044.6029 1.38 50788 18400 2 1044.606403 523.3087 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 8.75 3556.5 - 495224 - - - 3.3132 - 1.472 0.292 - 120.8 1 2 0 0.0035 9 0 0 0 6.23E+06 4.52E+06 - - - 2.3151 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18402.18402.2 0.00291 20-Aug R.ILMLGLDAAGK[136.11].T sp|P62330|ARF6_HUMAN 1 1108.6406 0.58 50790 18402 2 1108.64129 555.3276 ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2 5.84 3556.8 - 288156 - - - 0.6522 - 1.77 0.345 - 103.6 1 2 0 0.0007 11 0 0 0 4.22E+06 7.27E+06 - - - 3.1336 0.9953 230117_WJC_METTL3_WT_vs_EV_F06.18404.18404.2 0.0358 18-Sep K.ALQEFDLALR.G "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1174.6346 0.34 50792 18404 2 1174.640372 588.3246 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 4.37 3557 - 259527 - - - 4.8943 - 1.699 0.301 - 196.3 1 2 0 0.0057 10 0 0 0 3.47E+06 1.03E+07 - - - 2.7419 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18411.18411.2 0.0248 16-Oct R.LYSVSYLLK[136.11].D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1092.631 0.74 50797 18411 2 1092.632523 547.3228 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.5 3558 - 3.28E+06 - - - 1.35 - 1.949 0.409 - 264.9 1 2 0 0.0015 9 0 0 0 1.52E+07 2.06E+07 - - - 3.992 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18412.18412.2 8.08E-05 16-Nov K.LEVDIPLVK[136.11].S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1032.631 4.23 50798 18412 2 1032.632561 517.3228 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3558.1 - 3.39E+06 - - - 1.4652 - 2.023 0.453 - 359.5 1 2 0 0.0015 9 0 0 0 7.78E+07 1.84E+07 - - - 4.4248 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18413.18413.2 8.01E-06 22-Nov K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 0.88 50799 18413 2 1252.75344 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3558.2 - 1.99E+06 - - - 2.4889 - 2.326 0.34 - 510.1 1 2 0 0.0031 12 0 0 0 2.46E+07 2.79E+07 - - - 3.7724 0.9296 230117_WJC_METTL3_WT_vs_EV_F06.18414.18414.2 0.281 12-Jun R.EIFITFR.V sp|Q96EY1|DNJA3_HUMAN 1 924.5069 1.58 50800 18414 2 924.511238 463.2607 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.1 3558.4 - 1.59E+06 - - - 4.689 - 1.137 0.131 - 122.3 2 2 0 0.0043 7 0 0 0 1.31E+07 8.30E+06 - - - 0.2796 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.18417.18417.2 0.0889 16-Sep R.SLIAEVLVK.L sp|O95969|SG1D2_HUMAN 1 970.6063 179.68 50803 18417 2 970.609889 486.3104 Secretoglobin family 1D member 2 OS=Homo sapiens OX=9606 GN=SCGB1D2 PE=2 SV=1 5.72 3558.7 - 830342 - - - 3.7152 - 1.641 0.288 - 217.4 1 2 0 0.0036 9 0 0 0 8.92E+06 4.96E+04 - - - 2.6 0.8649 230117_WJC_METTL3_WT_vs_EV_F06.18418.18418.2 0.328 14-Sep V.ILSILLSK.A "sp|Q6UXB4|CLC4G_HUMAN,sp|Q02040|AK17A_HUMAN,tr|A0A7I2V4C7|A0A7I2V4C7_HUMAN,tr|M0R277|M0R277_HUMAN,tr|A0A7I2V4U5|A0A7I2V4U5_HUMAN" 5 885.5899 1.09 50804 18418 2 885.59323 443.8022 C-type lectin domain family 4 member G OS=Homo sapiens OX=9606 GN=CLEC4G PE=1 SV=1 8.75 3558.9 - 799774 - - - 3.7546 - 1.885 0.258 - 210.3 1 1 0 0.0033 8 0 0 0 4.27E+06 3.91E+06 - - - 2.8574 0.9935 230117_WJC_METTL3_WT_vs_EV_F06.18419.18419.2 0.304 14-Aug K.VALLLLEK[136.11].E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 905.6041 1.18 50805 18419 2 905.607074 453.8093 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3559 - 768442 - - - 3.2785 - 1.735 0.091 - 181.9 1 2 0 0.003 8 0 0 0 1.39E+07 1.18E+07 - - - 1.374 1 230117_WJC_METTL3_WT_vs_EV_F06.18421.18421.2 1.83E-06 15/22 K.AFAVGVQQVLLK.V sp|O95373|IPO7_HUMAN 1 1271.7602 1.92 50807 18421 2 1271.76355 636.8874 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 8.8 3559.3 - 403343 - - - 2.6672 - 2.749 0.582 - 766.1 1 2 0 0.0034 12 0 0 0 7.34E+06 3.83E+06 - - - 5.9993 0.9951 230117_WJC_METTL3_WT_vs_EV_F06.18422.18422.2 0.0683 14-Aug R.LYLLQGIR.N "sp|Q9Y5A7|NUB1_HUMAN,tr|H3BM74|H3BM74_HUMAN,tr|H3BM14|H3BM14_HUMAN" 3 974.5913 2.12 50808 18422 2 974.595995 488.3029 NEDD8 ultimate buster 1 OS=Homo sapiens OX=9606 GN=NUB1 PE=1 SV=2 8.75 3559.4 - 754854 - - - 4.8154 - 1.639 0.284 - 203.9 1 2 0 0.0047 8 0 0 0 2.73E+06 1.29E+06 - - - 2.6273 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.18423.18423.2 0.00366 20-Nov R.LPPEFSPVIIK[136.11].E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1246.7417 0.15 50809 18423 2 1246.744708 624.3781 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6 3559.5 - 324679 - - - 2.444 - 1.712 0.281 - 301.4 1 2 0 0.003 11 0 0 0 8.40E+05 5.75E+06 - - - 2.57 1 230117_WJC_METTL3_WT_vs_EV_F06.18426.18426.2 9.17E-06 22-Nov K.AFAVGVQQVLLK[136.11].V sp|O95373|IPO7_HUMAN 1 1279.7744 1.92 50812 18426 2 1279.777036 640.8945 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 8.8 3559.9 - 277798 - - - 2.0926 - 2.253 0.564 - 379 1 2 0 0.0027 12 0 0 0 7.34E+06 3.83E+06 - - - 5.3431 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.18436.18436.2 0.0272 14-Sep K.SYYLGLLR.S "sp|Q96LB3|IFT74_HUMAN,tr|E5RJK3|E5RJK3_HUMAN,tr|E5RGX6|E5RGX6_HUMAN,tr|A0A3B3IT46|A0A3B3IT46_HUMAN,tr|E5RIF0|E5RIF0_HUMAN,tr|E5RH29|E5RH29_HUMAN" 6 983.544 1.95 50821 18436 2 983.547818 492.7793 Intraflagellar transport protein 74 homolog OS=Homo sapiens OX=9606 GN=IFT74 PE=1 SV=1 8.31 3561.1 - 387628 - - - 3.8646 - 1.65 0.284 - 357.3 1 2 0 0.0038 8 0 0 0 5.10E+06 2.61E+06 - - - 2.6477 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.18438.18438.2 0.0595 12-Aug R.NYLSIFR.K sp|P07384|CAN1_HUMAN 1 911.4865 26.71 50823 18438 2 911.489061 456.7505 Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1 8.75 3561.3 - 324604 - - - 2.8075 - 1.482 0.223 - 243.3 1 2 0 0.0026 7 0 0 0 1.73E+07 6.47E+05 - - - 1.9338 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.18441.18441.2 0.329 12-Jul R.DLFALAR[166.11].K sp|Q9Y4W6|AFG32_HUMAN 1 814.4577 1.56 50826 18441 2 814.458826 408.2361 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.84 3561.7 - 197471 - - - 1.4341 - 1.264 0.194 - 221.9 1 2 0 0.0012 7 0 0 0 8.18E+06 5.25E+06 - - - 1.2159 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.18446.18446.2 0.0426 18-May K.FYALDPSFPR[166.11].M sp|Q08J23|NSUN2_HUMAN 1 1221.6058 2.19 50830 18446 2 1221.607765 611.8102 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3562.3 - 307038 - - - 1.6257 - 1.26 0.304 - 77.1 1 2 0 0.002 10 0 0 0 8.53E+06 3.90E+06 - - - 1.9308 0.9953 230117_WJC_METTL3_WT_vs_EV_F06.18450.18450.2 0.251 12-Jul R.DLFALAR.K sp|Q9Y4W6|AFG32_HUMAN 1 804.4494 1.56 50834 18450 2 804.450077 403.232 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.84 3562.7 - 828373 - - - 0.8565 - 1.227 0.186 - 218.6 1 2 0 0.0007 7 0 0 0 8.18E+06 5.25E+06 - - - 1.0628 1 230117_WJC_METTL3_WT_vs_EV_F06.18451.18451.2 0.000166 18-Oct R.VLLMELEEAR[166.11].G sp|P12270|TPR_HUMAN 1 1211.6459 1.4 50835 18451 2 1211.646363 606.8302 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3562.8 - 757694 - - - 0.3574 - 2.195 0.466 - 399.2 1 2 0 0.0004 10 0 0 0 3.34E+07 2.38E+07 - - - 4.6772 0.9171 230117_WJC_METTL3_WT_vs_EV_F06.18452.18452.2 0.828 12-May K.DFISVLR[166.11].G sp|Q9Y3B9|RRP15_HUMAN 1 858.4839 0.92 50836 18452 2 858.485692 430.2492 RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2 5.84 3562.9 - 716686 - - - 2.1189 - 1.126 0.002 - 113.7 4 2 0 0.0018 7 0 0 0 1.85E+07 2.00E+07 - - - -0.8377 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18453.18453.2 0.000201 18-Aug K.VFLSGMPELR.L "sp|Q9Y6Q5|AP1M2_HUMAN,sp|Q9BXS5|AP1M1_HUMAN,tr|E7ENJ6|E7ENJ6_HUMAN,tr|K7EJL1|K7EJL1_HUMAN,tr|K7EJJ1|K7EJJ1_HUMAN,tr|K7EMG5|K7EMG5_HUMAN,tr|K7EPR4|K7EPR4_HUMAN" 7 1147.606 0.94 50837 18453 2 1147.607539 574.8103 AP-1 complex subunit mu-2 OS=Homo sapiens OX=9606 GN=AP1M2 PE=1 SV=4 5.97 3563.1 - 601687 - - - 1.3716 - 1.808 0.474 - 222.7 1 2 0 0.0016 10 0 0 0 3.29E+06 3.50E+06 - - - 4.1945 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.18454.18454.2 0.21 18-Sep K.ALQEFDLALR[166.11].G "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1184.6429 0.18 50838 18454 2 1184.644093 593.3287 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 4.37 3563.2 - 591892 - - - 1.013 - 1.645 0.247 - 262 1 2 0 0.0012 10 0 0 0 1.23E+06 6.72E+06 - - - 2.2543 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18455.18455.2 0.00512 16-Oct K.LLQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1118.5748 13.17 50839 18455 2 1118.577247 560.2947 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3563.3 - 349458 - - - 2.176 - 2.006 0.389 - 315.7 1 2 0 0.0024 9 0 0 0 4.74E+08 3.60E+07 - - - 3.9274 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.18463.18463.2 0.00748 12-Sep K.C[160.03]ALDFFR.Q sp|P51970|NDUA8_HUMAN 1 927.4273 1.41 50845 18463 2 927.430841 464.7209 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3564.4 - 1.80E+06 - - - 3.8472 - 1.801 0.382 - 400.9 1 2 0 0.0036 7 0 0 0 2.27E+07 1.61E+07 - - - 3.7255 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.18464.18464.2 0.00289 12-Sep K.C[160.03]ALDFFR[166.11].Q sp|P51970|NDUA8_HUMAN 1 937.4355 1.41 50846 18464 2 937.439159 469.725 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3564.5 - 1.51E+06 - - - 3.8573 - 1.872 0.356 - 443.5 1 2 0 0.0036 7 0 0 0 2.27E+07 1.61E+07 - - - 3.656 0.9928 230117_WJC_METTL3_WT_vs_EV_F06.18465.18465.2 0.00582 12-Jun R.TIFSYFK.G sp|Q9UJV9|DDX41_HUMAN 1 904.4695 1.17 50847 18465 2 904.472489 453.242 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 8.26 3564.6 - 1.40E+06 - - - 3.3545 - 1.324 0.19 - 96.8 1 2 0 0.003 7 0 0 0 3.63E+07 3.09E+07 - - - 1.3327 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.18466.18466.2 0.000145 22-Sep K.VIGPEPTGFLLK[136.11].F sp|Q8IUH4|ZDH13_HUMAN 1 1277.7475 0.77 50848 18466 2 1277.750929 639.881 Palmitoyltransferase ZDHHC13 OS=Homo sapiens OX=9606 GN=ZDHHC13 PE=1 SV=3 5.97 3564.8 - 946303 - - - 2.7032 - 1.614 0.429 - 145.6 1 2 0 0.0035 12 0 0 0 4.40E+06 5.68E+06 - - - 3.4681 0.9322 230117_WJC_METTL3_WT_vs_EV_F06.18467.18467.2 3.58 12-Jul R.QILLPFR.K "sp|Q02218|ODO1_HUMAN,sp|Q9ULD0|OGDHL_HUMAN,tr|E9PFG7|E9PFG7_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|A0A0D9SFS3|A0A0D9SFS3_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 6 885.5436 1.17 50849 18467 2 885.546097 443.7791 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 9.75 3564.9 - 851490 - - - 2.7938 - 1.201 0.013 - 157.8 3 2 0 0.0025 7 0 0 0 5.32E+06 4.54E+06 - - - -0.4966 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.18468.18468.2 0.00766 16-Sep K.LQDPFSLYR.C sp|P21912|SDHB_HUMAN 1 1137.5819 3.13 50850 18468 2 1137.584574 569.7982 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.84 3565 - 849251 - - - 2.3866 - 2.071 0.252 - 182.7 2 2 0 0.0027 9 0 0 0 4.36E+07 1.39E+07 - - - 2.8732 0.8726 230117_WJC_METTL3_WT_vs_EV_F06.18471.18471.2 0.0328 16-Jul R.GFIVESVLR.N sp|Q86UQ0|ZN589_HUMAN 1 1018.5811 2.92 50853 18471 2 1018.590683 510.2978 Zinc finger protein 589 OS=Homo sapiens OX=9606 GN=ZNF589 PE=1 SV=1 6 3565.4 - 470698 - - - 9.3778 - 1.751 0.116 - 138.4 1 2 0 0.0096 9 0 0 0 5.51E+06 1.89E+06 - - - 1.5154 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.18474.18474.2 0.064 16-Oct K.LALFQAIGK.E "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 959.5804 1.77 50856 18474 2 959.583695 480.7975 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 8.75 3565.8 - 255153 - - - 3.4307 - 2.005 0.317 - 214.5 2 2 0 0.0033 9 0 0 0 6.45E+06 3.65E+06 - - - 3.2594 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18478.18478.2 0.00647 18-Dec K.TLVQILTEPR[166.11].N sp|O76031|CLPX_HUMAN 1 1178.6898 2.17 50859 18478 2 1178.693871 590.3522 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3566.3 - 1.28E+06 - - - 3.4174 - 2.373 0.423 - 594.1 1 2 0 0.004 10 0 0 0 1.86E+07 8.55E+06 - - - 4.5761 0.9541 230117_WJC_METTL3_WT_vs_EV_F06.18480.18480.2 0.00389 13/20 F.IGAIAIGDLVK[136.11].S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1076.6685 6.5 50860 18480 2 1076.670607 539.3415 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 3566.5 - 1.98E+06 - - - 1.9607 - 2.131 0.271 - 369.3 1 1 0 0.0021 11 0 0 0 2.09E+08 3.22E+07 - - - 3.0887 0.9969 230117_WJC_METTL3_WT_vs_EV_F06.18481.18481.2 0.0158 14-Jul K.SIGDIFLK[136.11].Y "sp|Q9H8V3|ECT2_HUMAN,tr|H7C3G1|H7C3G1_HUMAN" 2 899.5208 0.93 50861 18481 2 899.522802 450.7677 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 5.55 3566.6 - 1.39E+06 - - - 2.2601 - 1.293 0.231 - 126.1 1 2 0 0.002 8 0 0 0 1.28E+07 1.38E+07 - - - 1.5215 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.18482.18482.2 0.0283 18-Jul K.FLALYLHGAA.- "sp|Q9BZE1|RM37_HUMAN,tr|A6NHR2|A6NHR2_HUMAN" 2 1074.5862 - 50862 18482 2 1074.589628 538.3004 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 6.74 3566.6 - 2.56E+06 - - - 3.1752 - 1.205 0.317 - 122.3 1 2 0 0.0034 10 0 0 0 - - - - - 1.9018 1 230117_WJC_METTL3_WT_vs_EV_F06.18483.18483.2 0.000144 13/18 K.TLVQILTEPR.N sp|O76031|CLPX_HUMAN 1 1168.6816 2.17 50863 18483 2 1168.685572 585.3481 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3566.7 - 1.09E+06 - - - 3.4218 - 2.277 0.478 - 789.4 1 2 0 0.004 10 0 0 0 1.86E+07 8.55E+06 - - - 4.8671 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.18486.18486.2 0.0037 22-Nov K.VIGPEPTGFLLK.F sp|Q8IUH4|ZDH13_HUMAN 1 1269.7333 0.77 50866 18486 2 1269.734444 635.8739 Palmitoyltransferase ZDHHC13 OS=Homo sapiens OX=9606 GN=ZDHHC13 PE=1 SV=3 5.97 3567.1 - 499811 - - - 0.9207 - 1.556 0.314 - 296.3 1 2 0 0.0012 12 0 0 0 4.40E+06 5.68E+06 - - - 2.5231 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18489.18489.2 3.37E-05 18-Oct K.LGMNLMNELK.Q "sp|Q16890|TPD53_HUMAN,tr|E9PNK6|E9PNK6_HUMAN,tr|E9PNQ9|E9PNQ9_HUMAN,tr|E9PPQ1|E9PPQ1_HUMAN,tr|J3KNE7|J3KNE7_HUMAN" 5 1161.5886 1.58 50869 18489 2 1161.59133 581.8016 Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1 6 3567.5 - 383709 - - - 2.3494 - 2.262 0.401 - 229.2 1 2 0 0.0027 10 0 0 0 5.88E+06 3.72E+06 - - - 4.2803 0.9889 230117_WJC_METTL3_WT_vs_EV_F06.18491.18491.2 0.218 20-Sep R.LPPEFSPVIIK.E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1238.7275 0.72 50871 18491 2 1238.732996 620.371 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6 3567.8 - 345087 - - - 4.4683 - 1.698 0.152 - 176 1 2 0 0.0055 11 0 0 0 8.11E+06 1.13E+07 - - - 1.5942 1 230117_WJC_METTL3_WT_vs_EV_F06.18494.18494.2 7.17E-07 24-Nov K.LFPDTPLALDANK[136.11].K sp|Q12906|ILF3_HUMAN 1 1421.7646 0.39 50874 18494 2 1421.774361 711.8896 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3568.2 - 190645 - - - 6.8788 - 1.97 0.54 - 385.2 1 2 0 0.0098 13 0 0 0 4.11E+06 1.06E+07 - - - 4.7666 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.18495.18495.2 0.0238 18-Jun R.NLLEYSYFEK.G "sp|Q8NE65|ZN738_HUMAN,tr|M0R024|M0R024_HUMAN,tr|A0A804HJ59|A0A804HJ59_HUMAN,tr|E9PE46|E9PE46_HUMAN,tr|M0R0N2|M0R0N2_HUMAN" 5 1304.6289 2.26 50875 18495 2 1304.629462 653.3217 Protein ZNF738 OS=Homo sapiens OX=9606 GN=ZNF738 PE=2 SV=1 4.53 3568.3 - 164129 - - - 0.4545 - 1.461 0.248 - 42.1 1 2 0 0.0006 10 0 0 0 1.27E+06 5.60E+05 - - - 1.9308 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.18500.18500.2 0.028 14-Aug R.LLLEEIYR[166.11].G "sp|Q9Y2P8|RCL1_HUMAN,tr|Q5VZU2|Q5VZU2_HUMAN,tr|Q5VZU3|Q5VZU3_HUMAN" 3 1057.6047 0.71 50878 18500 2 1057.607646 529.8096 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 4.53 3568.9 - 5.55E+06 - - - 2.7695 - 1.68 0.354 - 237.1 1 2 0 0.0029 8 0 0 0 1.62E+07 2.28E+07 - - - 3.2194 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18501.18501.2 0.00181 16-Oct R.ELGELIPLR.Q "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1038.6073 1.09 50879 18501 2 1038.610188 520.3109 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.53 3568.9 - 4.81E+06 - - - 2.7364 - 1.781 0.392 - 440.1 1 2 0 0.0028 9 0 0 0 1.74E+07 1.59E+07 - - - 3.6052 0.9961 230117_WJC_METTL3_WT_vs_EV_F06.18505.18505.2 0.288 14-Jul K.IGELFALR.H "sp|Q9NWS8|RMND1_HUMAN,tr|A0A804HHW6|A0A804HHW6_HUMAN,tr|A0A087WXU0|A0A087WXU0_HUMAN,tr|A0A2R8Y4J4|A0A2R8Y4J4_HUMAN,tr|A0A804HKF8|A0A804HKF8_HUMAN,tr|A0A804HLE1|A0A804HLE1_HUMAN" 6 917.5335 0.96 50883 18505 2 917.535674 459.774 Required for meiotic nuclear division protein 1 homolog OS=Homo sapiens OX=9606 GN=RMND1 PE=1 SV=2 6 3569.4 - 1.43E+06 - - - 2.4217 - 1.233 0.233 - 120.9 1 2 0 0.0022 8 0 0 0 4.31E+06 4.49E+06 - - - 1.3929 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18509.18509.2 2.79E-05 24-Dec K.LFPDTPLALDANK.K sp|Q12906|ILF3_HUMAN 1 1413.7504 0.49 50887 18509 2 1413.754645 707.8825 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3569.9 - 765212 - - - 3.0161 - 1.916 0.483 - 259.8 1 2 0 0.0043 13 0 0 0 3.94E+06 8.08E+06 - - - 4.276 0.9229 230117_WJC_METTL3_WT_vs_EV_F06.18510.18510.3 0.000103 16/44 K.IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1464.8307 0.42 50888 18510 3 1464.836681 489.2842 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3570 - 743096 - - - 4.0831 - 2.678 0.261 - 473.7 1 2 1 0.006 12 0 0 0 1.53E+06 3.60E+06 - - - 4.1787 0.9572 230117_WJC_METTL3_WT_vs_EV_F06.18511.18511.2 0.0111 20-Sep K.PLVVQVPTFAR.R sp|O00257|CBX4_HUMAN 1 1225.7183 3.36 50889 18511 2 1225.722134 613.8664 E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3 10.18 3570.1 - 590648 - - - 3.1337 - 2.121 0.432 - 274.8 1 1 0 0.0038 11 0 0 0 3.46E+06 1.03E+06 - - - 4.2646 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18514.18514.2 0.0005 16-Jul K.LLQDFFNGR.D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1108.5665 13.17 50891 18514 2 1108.57005 555.2905 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3570.5 - 1.92E+07 - - - 3.1635 - 1.62 0.543 - 184.7 1 2 0 0.0035 9 0 0 0 4.74E+08 3.60E+07 - - - 4.4462 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18517.18517.2 0.00429 22-Dec K.YILAATLDNTLK[136.11].L sp|P61964|WDR5_HUMAN 1 1342.7588 1.47 50894 18517 2 1342.761489 672.3867 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 5.83 3570.7 - 1.01E+06 - - - 2.0264 - 2.384 0.382 - 392 1 2 0 0.0027 12 0 0 0 1.96E+07 1.34E+07 - - - 4.1475 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.18518.18518.2 0.00679 12-Jun R.VWSDFLR.V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 921.4709 2.21 50895 18518 2 921.471986 461.7427 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.81 3570.8 - 776072 - - - 1.2306 - 1.353 0.296 - 180.3 1 2 0 0.0011 7 0 0 0 1.44E+07 6.50E+06 - - - 2.1848 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.18519.18519.2 0.000453 20-Nov K.LGLENAEALIR[166.11].L sp|P10155|RO60_HUMAN 1 1207.68 3.8 50896 18519 2 1207.686352 604.8473 60 kDa SS-A\Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2 4.53 3570.9 - 645685 - - - 5.2539 - 2.297 0.388 - 277.8 1 2 0 0.0063 11 0 0 0 2.85E+07 7.51E+06 - - - 4.1545 0.9657 230117_WJC_METTL3_WT_vs_EV_F06.18521.18521.2 4.48 14-Sep R.FLDINLYK.D sp|Q9NRF8|PYRG2_HUMAN 1 1024.5593 7.32 50898 18521 2 1024.561806 513.2869 CTP synthase 2 OS=Homo sapiens OX=9606 GN=CTPS2 PE=1 SV=1 5.83 3571.1 - 613781 - - - 2.4137 - 1.244 0.017 - 179.1 1 2 0 0.0025 8 0 0 0 1.00E+07 1.37E+06 - - - -0.1757 1 230117_WJC_METTL3_WT_vs_EV_F06.18524.18524.2 2.68E-05 17/28 R.LPAAGVGDMVMATVK[136.11].K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1466.7717 1.46 50901 18524 2 1466.767405 734.3931 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3571.5 - 265436 - - - -2.8989 - 3.548 0.543 - 1018.5 1 2 0 -0.0043 15 0 0 0 1.21E+08 8.30E+07 - - - 6.1637 0.9801 230117_WJC_METTL3_WT_vs_EV_F06.18525.18525.2 0.816 14-Jun K.IFELTELR[166.11].D "sp|Q86YM7|HOME1_HUMAN,tr|Q86YM6|Q86YM6_HUMAN" 2 1029.5734 0.45 50902 18525 2 1029.577561 515.794 Homer protein homolog 1 OS=Homo sapiens OX=9606 GN=HOMER1 PE=1 SV=2 4.53 3571.6 - 265507 - - - 4.025 - 1.252 0.158 - 71 1 2 0 0.0041 8 0 0 0 7.57E+05 1.68E+06 - - - 0.8845 0.998 230117_WJC_METTL3_WT_vs_EV_F06.18526.18526.2 0.222 22-Oct K.LLHSDLAPTLLE.- sp|Q6ZQX7|LIAT1_HUMAN 1 1320.7289 - 50903 18526 2 1320.731998 661.3717 Protein LIAT1 OS=Homo sapiens OX=9606 GN=LIAT1 PE=1 SV=2 4.71 3571.7 - 222475 - - - 2.3328 - 1.903 0.16 - 303.3 1 2 0 0.0031 12 0 0 0 - - - - - 1.9148 0.999 230117_WJC_METTL3_WT_vs_EV_F06.18530.18530.2 0.0632 18-Nov R.LGLLGLPAPK.N sp|Q99459|CDC5L_HUMAN 1 977.6274 1.23 50905 18530 2 977.62896 489.821 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3572.3 - 1.79E+06 - - - 1.6438 - 2.283 0.141 - 282.2 1 2 0 0.0016 10 0 0 0 8.95E+07 7.27E+07 - - - 2.3861 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.18532.18532.2 0.0199 14-Jul R.LLLEEIYR.G "sp|Q9Y2P8|RCL1_HUMAN,tr|Q5VZU2|Q5VZU2_HUMAN,tr|Q5VZU3|Q5VZU3_HUMAN" 3 1047.5964 0.71 50907 18532 2 1047.59842 524.8055 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 4.53 3572.4 - 1.51E+06 - - - 1.8834 - 1.677 0.261 - 187.5 1 2 0 0.002 8 0 0 0 1.62E+07 2.28E+07 - - - 2.5274 0.9572 230117_WJC_METTL3_WT_vs_EV_F06.18533.18533.2 0.952 12-Apr R.VWSDFLR[166.11].V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 931.4791 2.25 50908 18533 2 931.480386 466.7468 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.81 3572.4 - 1.28E+06 - - - 1.357 - 1.048 0.117 - 43.3 17 2 0 0.0013 7 0 0 0 1.46E+07 6.50E+06 - - - -0.4963 1 230117_WJC_METTL3_WT_vs_EV_F06.18535.18535.2 3.60E-06 19/28 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 1.46 50910 18535 2 1458.759869 730.386 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3572.6 - 1.18E+06 - - - 1.6535 - 3.824 0.609 - 1452.8 1 2 0 0.0024 15 0 0 0 1.21E+08 8.30E+07 - - - 6.836 0.982 230117_WJC_METTL3_WT_vs_EV_F06.18537.18537.2 0.00312 18-Sep K.FFWGNAETLK.H "sp|O43847|NRDC_HUMAN,tr|G3V1R5|G3V1R5_HUMAN,tr|F5H7V1|F5H7V1_HUMAN" 3 1211.5975 1.7 50912 18537 2 1211.600493 606.806 Nardilysin OS=Homo sapiens OX=9606 GN=NRDC PE=1 SV=3 6 3572.8 - 670524 - - - 2.4629 - 1.295 0.069 - 162.7 1 2 0 0.003 10 0 0 0 5.86E+06 3.45E+06 - - - 0.2713 0.9944 230117_WJC_METTL3_WT_vs_EV_F06.18539.18539.2 0.0154 14-Jul R.SFYLALYK.Q "sp|Q9BQ70|TCF25_HUMAN,tr|Q9H384|Q9H384_HUMAN,tr|H3BSS3|H3BSS3_HUMAN,tr|H3BQ53|H3BQ53_HUMAN" 4 1003.5379 0.14 50914 18539 2 1003.53815 502.7762 Transcription factor 25 OS=Homo sapiens OX=9606 GN=TCF25 PE=1 SV=1 8.22 3573.1 - 441507 - - - 0.28 - 1.278 0.176 - 140.3 1 2 0 0.0003 8 0 0 0 3.04E+06 2.18E+07 - - - 1.0807 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.18540.18540.3 1.54E-07 14/56 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 1.61 50915 18540 3 1458.760844 487.2598 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3573.2 - 431309 - - - 2.3218 - 2.835 0.368 - 284.7 1 2 0 0.0034 15 0 0 0 3.20E+07 1.99E+07 - - - 5.361 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.18552.18552.2 0.0484 18-Jun R.LGLLGLPAPK[136.11].N sp|Q99459|CDC5L_HUMAN 1 985.6416 1.2 50925 18552 2 985.64283 493.8281 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3574.7 - 8.31E+06 - - - 1.2956 - 1.646 0.15 - 82.9 1 2 0 0.0013 10 0 0 0 8.11E+07 6.78E+07 - - - 1.5395 1 230117_WJC_METTL3_WT_vs_EV_F06.18553.18553.2 1.24E-09 16/30 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 15.19 50926 18553 2 1686.897623 844.4543 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3574.8 - 4.38E+06 - - - 2.0973 - 3.16 0.622 - 650.5 1 2 0 0.0035 16 0 0 0 5.13E+07 3.38E+06 - - - 6.4627 1 230117_WJC_METTL3_WT_vs_EV_F06.18554.18554.2 9.62E-07 20-Dec R.LYEAYLPETFR.R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1400.6976 2.27 50927 18554 2 1400.701368 701.3561 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3574.8 - 6.39E+06 - - - 2.678 - 2.359 0.496 - 605.9 1 2 0 0.0037 11 0 0 0 4.35E+07 1.92E+07 - - - 5.025 1 230117_WJC_METTL3_WT_vs_EV_F06.18555.18555.3 8.63E-10 23/60 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 21.89 50928 18555 3 1686.897666 563.3053 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3574.8 - 3.44E+06 - - - 2.1228 - 3.962 0.619 - 726.8 1 2 0 0.0036 16 0 0 0 3.98E+07 1.82E+06 - - - 8.9728 1 230117_WJC_METTL3_WT_vs_EV_F06.18556.18556.2 6.05E-05 13/20 R.LYEAYLPETFR[166.11].R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1410.7059 2.27 50929 18556 2 1410.709313 706.3602 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3574.9 - 2.91E+06 - - - 2.4286 - 2.344 0.528 - 463.5 1 2 0 0.0034 11 0 0 0 4.35E+07 1.92E+07 - - - 5.2442 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.18558.18558.2 0.000149 14-Sep K.MDELQLFR.G "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0T971|A0A7P0T971_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7P0Z4D1|A0A7P0Z4D1_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0T946|A0A7P0T946_HUMAN,tr|A0A7P0TBK7|A0A7P0TBK7_HUMAN" 14 1050.5168 0.99 50931 18558 2 1050.519005 526.2657 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.37 3575 - 2.35E+06 - - - 2.0837 - 2.125 0.224 - 480.5 1 2 0 0.0022 8 0 0 0 1.32E+07 1.33E+07 - - - 2.9681 0.9865 230117_WJC_METTL3_WT_vs_EV_F06.18560.18560.2 0.000891 14-Aug K.YLELLGYR[166.11].K "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 7 1035.5629 1.42 50933 18560 2 1035.565755 518.7887 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6 3575.1 - 1.24E+06 - - - 2.8033 - 1.675 0.001 - 197.6 1 2 0 0.0029 8 0 0 0 9.92E+06 6.98E+06 - - - 0.6031 0.9735 230117_WJC_METTL3_WT_vs_EV_F06.18561.18561.2 4.32 12-Jun K.DLLLPIK.T "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 3 810.5215 1.59 50934 18561 2 810.52258 406.268 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 5.84 3575.2 - 1.04E+06 - - - 1.3436 - 1.268 0.003 - 149.2 1 2 0 0.0011 7 0 0 0 1.62E+07 1.01E+07 - - - -0.1848 0.9827 230117_WJC_METTL3_WT_vs_EV_F06.18562.18562.2 2.94 12-Jul K.DLLLPIK[136.11].T "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 3 818.5357 1.62 50935 18562 2 818.536662 410.2751 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 5.84 3575.4 - 764541 - - - 1.1863 - 1.391 0.002 - 209.6 1 2 0 0.001 7 0 0 0 1.62E+07 9.98E+06 - - - 0.1012 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18563.18563.2 0.00792 18-Nov K.TNVALMC[160.03]MLR[166.11].E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1217.5958 0.95 50936 18563 2 1217.598243 609.8052 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 7.91 3575.4 - 728622 - - - 1.9859 - 2.079 0.45 - 576.7 1 2 0 0.0024 10 0 0 0 4.57E+06 4.83E+06 - - - 4.4069 1 230117_WJC_METTL3_WT_vs_EV_F06.18564.18564.2 2.61E-05 20-Dec K.VIAEDEVLWYR.L "sp|Q8N3Y1|FBXW8_HUMAN,tr|A0A499FIY5|A0A499FIY5_HUMAN" 2 1391.7085 6.67 50937 18564 2 1391.710465 696.8615 F-box\WD repeat-containing protein 8 OS=Homo sapiens OX=9606 GN=FBXW8 PE=1 SV=2 4.14 3575.6 - 638944 - - - 1.4004 - 2.287 0.457 - 459.5 1 2 0 0.0019 11 0 0 0 3.15E+06 4.72E+05 - - - 4.6537 1 230117_WJC_METTL3_WT_vs_EV_F06.18567.18567.2 5.71E-05 20-Dec K.LALDMEIATYR.K "sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|Q14CN4|K2C72_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 4 1294.6591 20.46 50940 18567 2 1294.659621 648.3368 "Keratin, type II cytoskeletal 74 OS=Homo sapiens OX=9606 GN=KRT74 PE=1 SV=2" 4.37 3575.9 - 491090 - - - 0.3847 - 2.657 0.44 - 704.1 1 2 0 0.0005 11 0 0 0 3.50E+06 1.71E+05 - - - 4.9342 0.9923 230117_WJC_METTL3_WT_vs_EV_F06.18569.18569.2 0.242 14-Jun R.WVVPVLPK[136.11].G "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 944.5939 1.98 50942 18569 2 944.596706 473.3042 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3576.2 - 441477 - - - 2.9981 - 1.234 0.245 - 67.3 7 2 0 0.0028 8 0 0 0 8.70E+06 4.38E+06 - - - 1.1063 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18571.18571.2 0.0113 12-Sep R.LQFLFAK.D "sp|Q7Z3K3|POGZ_HUMAN,tr|H0YCT3|H0YCT3_HUMAN" 2 865.5062 1.05 50944 18571 2 865.50712 433.7604 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 8.75 3576.4 - 370402 - - - 1.0918 - 1.693 0.317 - 242.5 1 2 0 0.0009 7 0 0 0 5.03E+06 4.81E+06 - - - 3.0503 0.9856 230117_WJC_METTL3_WT_vs_EV_F06.18573.18573.2 3.09 12-Jun R.LFLEFER[166.11].K "sp|O43663|PRC1_HUMAN,sp|Q96I25|SPF45_HUMAN,tr|H0YL53|H0YL53_HUMAN" 3 962.5101 2.18 50945 18573 2 962.514113 482.2623 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 3576.6 - 449325 - - - 4.1818 - 1.259 0.196 - 107.6 1 2 0 0.004 7 0 0 0 1.80E+07 8.28E+06 - - - 1.2172 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.18574.18574.2 0.196 12-May R.LQFLFAK[136.11].D "sp|Q7Z3K3|POGZ_HUMAN,tr|H0YCT3|H0YCT3_HUMAN" 2 873.5204 1.37 50946 18574 2 873.521087 437.7675 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 8.75 3576.8 - 505202 - - - 0.8151 - 1.357 0.216 - 68.8 2 2 0 0.0007 7 0 0 0 4.97E+06 3.64E+06 - - - 1.469 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.18575.18575.2 0.0169 14-Aug R.EALAFIIR[166.11].S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 941.5574 1.12 50947 18575 2 941.55992 471.786 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3576.9 - 1.03E+06 - - - 2.7062 - 1.826 0.262 - 242.4 1 2 0 0.0025 8 0 0 0 2.54E+07 2.27E+07 - - - 2.7913 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.18577.18577.2 0.000689 18-Nov K.TNVALMC[160.03]MLR.E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1207.5876 0.9 50949 18577 2 1207.59392 604.8011 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 7.91 3577 - 935116 - - - 5.2708 - 2.16 0.429 - 434.5 1 2 0 0.0064 10 0 0 0 4.35E+06 4.83E+06 - - - 4.3572 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.18578.18578.2 0.0341 16-Aug M.AILFAVVAR.G "sp|P51809|VAMP7_HUMAN,tr|E5RH06|E5RH06_HUMAN" 2 958.5964 0.76 50950 18578 2 958.599415 480.3055 Vesicle-associated membrane protein 7 OS=Homo sapiens OX=9606 GN=VAMP7 PE=1 SV=3 9.79 3577.2 - 619800 - - - 3.1588 - 1.747 0.276 - 151.8 1 2 0 0.003 9 0 0 0 4.91E+06 6.50E+06 - - - 2.6926 1 230117_WJC_METTL3_WT_vs_EV_F06.18579.18579.2 1.47E-06 13/30 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 17.86 50951 18579 2 1696.906011 849.4585 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3577.3 - 542618 - - - 2.1545 - 2.769 0.556 - 456.5 1 2 0 0.0037 16 0 0 0 6.18E+07 3.46E+06 - - - 5.6505 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.18580.18580.2 0.038 16-Aug R.LFENYIELK.A sp|Q96KP1|EXOC2_HUMAN 1 1167.6176 0.74 50952 18580 2 1167.621427 584.8161 Exocyst complex component 2 OS=Homo sapiens OX=9606 GN=EXOC2 PE=1 SV=1 4.53 3577.4 - 526559 - - - 3.2982 - 1.65 0.319 - 159.5 1 2 0 0.0039 9 0 0 0 2.51E+06 3.40E+06 - - - 2.8447 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18581.18581.2 0.000243 20-Aug R.IFVFEPPPGVK[136.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 1236.6998 1.91 50953 18581 2 1236.701495 619.3572 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3577.6 - 468843 - - - 1.3738 - 1.753 0.405 - 171.6 1 2 0 0.0017 11 0 0 0 6.13E+07 3.20E+07 - - - 3.5503 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18582.18582.2 0.00091 22-Nov K.GGIVGMTLPIAR.D "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 1183.6747 1.51 50954 18582 2 1183.677342 592.8446 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 9.75 3577.7 - 399282 - - - 2.2202 - 1.865 0.431 - 318.8 1 2 0 0.0026 12 0 0 0 1.85E+07 1.22E+07 - - - 3.8634 0.9916 230117_WJC_METTL3_WT_vs_EV_F06.18590.18590.2 3.75E-06 18-Sep R.YLNWIGVPTK[136.11].V "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|A0A1W2PNV9|A0A1W2PNV9_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN,tr|F6XNB3|F6XNB3_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 9 1197.6637 0.18 50961 18590 2 1197.670679 599.8391 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.59 3578.7 - 2.37E+06 - - - 5.7896 - 1.821 0.28 - 242.5 1 2 0 0.0069 10 0 0 0 5.65E+06 3.14E+07 - - - 2.78 1 230117_WJC_METTL3_WT_vs_EV_F06.18591.18591.2 2.81E-07 22-Nov K.FGEAIGMGFPVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1251.6322 0.97 50962 18591 2 1251.635688 626.8234 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3578.7 - 3.22E+06 - - - 2.8027 - 2.141 0.528 - 351 1 2 0 0.0035 12 0 0 0 2.33E+08 2.41E+08 - - - 4.9427 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.18593.18593.2 0.0132 16-Aug R.TTLLPGLLK.T sp|Q9NSD9|SYFB_HUMAN 1 954.6114 4.02 50964 18593 2 954.613648 478.313 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 8.41 3578.9 - 2.43E+06 - - - 2.3884 - 1.469 0.232 - 213.8 1 2 0 0.0023 9 0 0 0 2.18E+07 5.42E+06 - - - 1.8665 0.997 230117_WJC_METTL3_WT_vs_EV_F06.18594.18594.2 0.00177 18-Oct R.VLGLGLGC[160.03]LR.L "sp|Q9BRJ7|TIRR_HUMAN,tr|W4VSQ8|W4VSQ8_HUMAN,tr|K7EIN2|K7EIN2_HUMAN,tr|K7ENA3|K7ENA3_HUMAN" 4 1056.6114 3.73 50965 18594 2 1056.616593 529.313 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3578.9 - 1.88E+06 - - - 4.929 - 1.952 0.335 - 285.5 1 2 0 0.0052 10 0 0 0 1.64E+07 4.40E+06 - - - 3.3807 0.999 230117_WJC_METTL3_WT_vs_EV_F06.18596.18596.2 0.0256 14-Jul R.WVVPVLPK.G "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 936.5797 2.17 50967 18596 2 936.58181 469.2971 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3579.1 - 1.43E+06 - - - 2.2806 - 1.533 0.306 - 205.4 1 2 0 0.0021 8 0 0 0 9.64E+06 4.44E+06 - - - 2.5889 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18597.18597.2 0.000655 16-Sep R.MADFWLTEK.D sp|Q9NRX2|RM17_HUMAN 1 1139.5321 1.28 50968 18597 2 1139.535289 570.7733 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 4.37 3579.2 - 1.13E+06 - - - 2.7704 - 2.01 0.432 - 292.9 1 2 0 0.0032 9 0 0 0 9.05E+06 7.09E+06 - - - 4.2505 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.18605.18605.2 0.000174 20-Oct R.VYPQAVYFPIR.T "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1351.7289 2.04 50976 18605 2 1351.734999 676.8717 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.56 3580.1 - 231999 - - - 4.5431 - 2.207 0.453 - 471.3 1 2 0 0.0061 11 0 0 0 3.24E+06 1.59E+06 - - - 4.5265 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.18609.18609.2 0.00142 16-Jul R.LVLDWDSVR.A "sp|Q68EM7|RHG17_HUMAN,tr|C9IZD3|C9IZD3_HUMAN,tr|I3L4P6|I3L4P6_HUMAN" 3 1101.5819 2.32 50978 18609 2 1101.586063 551.7982 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4.21 3580.6 - 2.50E+06 - - - 3.8163 - 1.607 0.393 - 153.3 1 2 0 0.0042 9 0 0 0 3.59E+07 1.55E+07 - - - 3.3148 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.18611.18611.2 0.372 20-Sep K.LVFLGLDNAGK.T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1145.6445 1.55 50980 18611 2 1145.648114 573.8295 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3580.7 - 2.12E+06 - - - 3.1903 - 1.77 0.319 - 239.3 1 2 0 0.0037 11 0 0 0 4.71E+08 3.04E+08 - - - 2.9406 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.18612.18612.2 0.0143 22-Nov K.GGIVGMTLPIAR[166.11].D "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 1193.683 1.51 50981 18612 2 1193.687729 597.8488 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 9.75 3580.8 - 1.80E+06 - - - 3.9751 - 2.036 0.375 - 311.7 1 2 0 0.0047 12 0 0 0 1.85E+07 1.22E+07 - - - 3.68 1 230117_WJC_METTL3_WT_vs_EV_F06.18613.18613.2 0.000927 22-Dec R.LLYMAIDGVAPR[166.11].A sp|Q9H0D6|XRN2_HUMAN 1 1327.7198 1.07 50982 18613 2 1327.727963 664.8672 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3580.9 - 1.35E+06 - - - 6.176 - 2.486 0.492 - 552.5 1 2 0 0.0082 12 0 0 0 5.57E+07 5.19E+07 - - - 5.0685 1 230117_WJC_METTL3_WT_vs_EV_F06.18614.18614.2 5.65E-08 14/22 R.LLYMAIDGVAPR.A sp|Q9H0D6|XRN2_HUMAN 1 1317.7115 1.07 50983 18614 2 1317.715715 659.863 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3581 - 1.24E+06 - - - 3.204 - 2.555 0.509 - 895.6 1 2 0 0.0042 12 0 0 0 5.58E+07 5.20E+07 - - - 5.2673 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18615.18615.2 0.00303 14-Sep R.QAFYFALR[166.11].D "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1024.537 1.93 50984 18615 2 1024.540051 513.2758 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.75 3581.1 - 666116 - - - 3.0062 - 1.872 0.432 - 327.5 1 2 0 0.0031 8 0 0 0 1.22E+07 6.30E+06 - - - 4.1218 0.9055 230117_WJC_METTL3_WT_vs_EV_F06.18616.18616.2 0.0483 16-Jun R.MVNHFIAEF.K "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1106.5219 - 50985 18616 2 1106.52352 554.2682 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.22 3581.2 - 453196 - - - 1.4631 - 1.207 0.342 - 97.4 1 1 0 0.0016 9 0 0 0 - - - - - 2.1108 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.18622.18622.2 0.035 20-Jun R.VYPQAVYFPIR[166.11].T "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1361.7371 2.04 50991 18622 2 1361.738805 681.8758 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.56 3582 - 234588 - - - 1.2315 - 1.303 0.259 - 124 1 2 0 0.0017 11 0 0 0 3.24E+06 1.59E+06 - - - 1.6694 1 230117_WJC_METTL3_WT_vs_EV_F06.18623.18623.2 1.29E-06 13/22 R.GIYTGLSAGLLR.Q "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 1219.6925 0.37 50992 18623 2 1219.701059 610.8535 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 8.75 3582.2 - 233071 - - - 7.0403 - 2.143 0.576 - 398.9 1 2 0 0.0086 12 0 0 0 1.16E+07 3.13E+07 - - - 5.2981 1 230117_WJC_METTL3_WT_vs_EV_F06.18626.18626.2 1.39E-05 22-Dec R.VIQEGLEGLVLK.D sp|P49916|DNLI3_HUMAN 1 1296.7653 2.08 50995 18626 2 1296.770131 649.3899 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 4.53 3582.6 - 192395 - - - 3.7231 - 2.202 0.507 - 403.3 1 2 0 0.0048 12 0 0 0 2.12E+06 1.02E+06 - - - 4.8611 0.9286 230117_WJC_METTL3_WT_vs_EV_F06.18628.18628.2 1.99 16-Apr R.ILFLDPSGK[136.11].V sp|O95881|TXD12_HUMAN 1 996.5735 1.13 50996 18628 2 996.576144 499.294 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3582.8 - 297808 - - - 2.62 - 0.892 0.131 - 32.5 4 2 0 0.0026 9 0 0 0 4.44E+08 3.95E+08 - - - -0.5918 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18630.18630.2 0.00747 20-Sep K.LVFLGLDNAGK[136.11].T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1153.6587 1.55 50997 18630 2 1153.660071 577.8366 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3583 - 5.83E+06 - - - 1.2239 - 1.763 0.439 - 235.9 1 2 0 0.0014 11 0 0 0 4.70E+08 3.04E+08 - - - 3.8169 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.18631.18631.2 0.0128 14-Jul R.EALAFIIR.S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 931.5491 1.12 50998 18631 2 931.549687 466.7818 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3583.1 - 1.95E+06 - - - 0.628 - 1.68 0.273 - 202.8 1 2 0 0.0006 8 0 0 0 2.62E+07 2.34E+07 - - - 2.6219 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.18634.18634.2 0.144 12-Jun K.LIFYDLR[166.11].G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 948.5308 1.1 51001 18634 2 948.53232 475.2727 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3583.2 - 1.32E+06 - - - 1.5782 - 1.323 0.253 - 147.8 1 2 0 0.0015 7 0 0 0 5.98E+07 5.44E+07 - - - 1.7961 0.9887 230117_WJC_METTL3_WT_vs_EV_F06.18635.18635.2 0.217 12-Apr R.VLVWDLR[166.11].N "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 909.5312 1.74 51002 18635 2 909.532498 455.7729 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.81 3583.3 - 1.27E+06 - - - 1.4733 - 1.209 0.101 - 87.9 1 2 0 0.0013 7 0 0 0 7.47E+07 4.30E+07 - - - 0.3879 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.18637.18637.2 0.201 16-Aug R.ALLLSTYIK.F "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|A0A0G2JS82|A0A0G2JS82_HUMAN,tr|A0A0G2JQM1|A0A0G2JQM1_HUMAN" 4 1020.6219 1.05 51004 18637 2 1020.623105 511.3182 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 8.63 3583.4 - 741164 - - - 1.1483 - 1.705 0.215 - 152.5 2 2 0 0.0012 9 0 0 0 7.77E+06 7.42E+06 - - - 2.0378 0.9956 230117_WJC_METTL3_WT_vs_EV_F06.18640.18640.2 0.0094 16-Nov R.LNILDTLSK.F "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1015.5914 2.01 51007 18640 2 1015.596884 508.803 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 5.84 3583.7 - 798958 - - - 5.4382 - 1.938 0.319 - 344 1 2 0 0.0055 9 0 0 0 3.88E+06 1.94E+06 - - - 3.3096 0.9847 230117_WJC_METTL3_WT_vs_EV_F06.18641.18641.2 0.784 16-May R.GNLLLEQER[166.11].Q "sp|Q6ZSZ5|ARHGI_HUMAN,tr|A0A3B3IPE9|A0A3B3IPE9_HUMAN,tr|A0A590UK10|A0A590UK10_HUMAN,tr|M0QZS0|M0QZS0_HUMAN,tr|A0A087WZG4|A0A087WZG4_HUMAN,tr|A0A804CAZ4|A0A804CAZ4_HUMAN" 6 1080.5803 6.07 51008 18641 2 1080.581875 541.2974 Rho guanine nucleotide exchange factor 18 OS=Homo sapiens OX=9606 GN=ARHGEF18 PE=1 SV=4 4.53 3583.8 - 451542 - - - 1.464 - 1.326 0.062 - 89.2 2 2 0 0.0016 9 0 0 0 4.98E+07 8.21E+06 - - - 0.1803 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18644.18644.2 0.00157 22-Aug R.VIQEGLEGLVLK[136.11].D sp|P49916|DNLI3_HUMAN 1 1304.7795 2.08 51011 18644 2 1304.780592 653.397 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 4.53 3584.2 - 220877 - - - 0.8346 - 1.689 0.388 - 170.7 1 2 0 0.0011 12 0 0 0 2.12E+06 1.02E+06 - - - 3.2855 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.18647.18647.2 0.0382 12-Jul K.LIFYDLR.G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 938.5226 1.1 51012 18647 2 938.524514 470.2686 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3584.6 - 3.43E+06 - - - 2.0895 - 1.458 0.34 - 204 1 2 0 0.002 7 0 0 0 5.98E+07 5.45E+07 - - - 2.7464 0.9948 230117_WJC_METTL3_WT_vs_EV_F06.18648.18648.2 0.279 14-Jun R.ILFFNTPK[136.11].K "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 986.5681 1.41 51013 18648 2 986.570419 494.2913 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 8.75 3584.6 - 2.68E+06 - - - 2.3972 - 1.316 0.173 - 68.5 1 2 0 0.0024 8 0 0 0 9.33E+07 6.63E+07 - - - 1.1462 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.18653.18653.2 0.00026 14-Sep K.C[160.03]QLLFALK.V "sp|Q9BRJ7|TIRR_HUMAN,tr|K7EIN2|K7EIN2_HUMAN" 2 991.5525 0.94 51018 18653 2 991.549154 496.7835 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3585.1 - 723264 - - - -3.3483 - 1.823 0.461 - 280.6 1 2 0 -0.0033 8 0 0 0 1.35E+07 1.43E+07 - - - 4.2559 0.9934 230117_WJC_METTL3_WT_vs_EV_F06.18655.18655.2 2.1 12-Jul R.TLIGFLR.S "sp|O15116|LSM1_HUMAN,tr|E5RH18|E5RH18_HUMAN,tr|E5RJ47|E5RJ47_HUMAN" 3 818.5014 1.58 51020 18655 2 818.502488 410.258 U6 snRNA-associated Sm-like protein LSm1 OS=Homo sapiens OX=9606 GN=LSM1 PE=1 SV=1 9.41 3585.3 - 456129 - - - 1.2999 - 1.25 0.138 - 197.7 1 2 0 0.0011 7 0 0 0 1.69E+07 1.08E+07 - - - 0.767 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18661.18661.2 0.000224 20-Aug R.VLPSITTEILK.S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1212.7329 1.45 51024 18661 2 1212.735262 607.3737 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 3586 - 2.45E+06 - - - 1.9147 - 1.769 0.487 - 224.1 1 2 0 0.0023 11 0 0 0 3.80E+08 2.62E+08 - - - 4.1804 0.9812 230117_WJC_METTL3_WT_vs_EV_F06.18662.18662.2 2.94 20-Jun R.VLPSITTEILK[136.11].S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1220.7471 1.45 51025 18662 2 1220.749282 611.3808 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 3586.1 - 1.75E+06 - - - 1.7547 - 1.122 0.097 - 78.7 1 2 0 0.0021 11 0 0 0 3.80E+08 2.62E+08 - - - 0.0682 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.18665.18665.2 0.0218 12-Jun R.EFIEMWR[166.11].L "sp|Q7L0Y3|TM10C_HUMAN,tr|C9JVB6|C9JVB6_HUMAN" 2 1019.4774 0.83 51028 18665 2 1019.478567 510.746 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 4.53 3586.3 - 882663 - - - 1.1369 - 1.367 0.284 - 148.7 1 2 0 0.0012 7 0 0 0 8.80E+06 1.06E+07 - - - 2.1288 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.18668.18668.2 0.0209 16-Aug R.VLAINILGR.F sp|O43747|AP1G1_HUMAN 1 967.6179 0.25 51031 18668 2 967.618348 484.8162 AP-1 complex subunit gamma-1 OS=Homo sapiens OX=9606 GN=AP1G1 PE=1 SV=5 9.72 3586.5 - 552286 - - - 0.5136 - 1.754 0.267 - 176.8 1 2 0 0.0005 9 0 0 0 6.27E+06 2.47E+07 - - - 2.6385 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.18672.18672.2 0.0538 18-Aug R.LWTPPEDYRL.- "sp|Q9BYD1|RM13_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 2 1288.6452 1.58 51035 18672 2 1288.645848 645.3299 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.37 3586.9 - 299674 - - - 0.5122 - 1.715 0.229 - 171 1 2 0 0.0007 10 0 0 0 2.00E+07 1.27E+07 - - - 2.2379 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.18674.18674.2 0.0934 18-Jun R.LWTPPEDYR[166.11]L.- "sp|Q9BYD1|RM13_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 2 1298.6535 1.56 51037 18674 2 1298.653323 650.334 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.37 3587.1 - 157388 - - - -0.104 - 1.451 0.251 - 143.7 1 2 0 -0.0001 10 0 0 0 1.98E+07 1.26E+07 - - - 1.9339 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18677.18677.2 1.87E-05 18-Oct K.ELLTSFGPLK[136.11].A "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1111.6369 1.6 51038 18677 2 1111.639739 556.8257 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6.1 3587.5 - 4.50E+06 - - - 2.589 - 2.092 0.462 - 335.1 1 2 0 0.0029 10 0 0 0 7.21E+07 4.51E+07 - - - 4.5127 0.9931 230117_WJC_METTL3_WT_vs_EV_F06.18678.18678.2 0.297 14-Jun R.FLIQNVLR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1011.6105 1.46 51039 18678 2 1011.612661 506.8125 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.75 3587.6 - 1.72E+06 - - - 2.1649 - 1.382 0.114 - 121.1 1 2 0 0.0022 8 0 0 0 1.29E+08 8.82E+07 - - - 0.8581 0.9786 230117_WJC_METTL3_WT_vs_EV_F06.18680.18680.2 0.583 18-Jul K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.21 51041 18680 2 1086.647896 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3587.9 - 793503 - - - 3.8329 - 1.513 0.073 - 100.7 1 2 0 0.0042 10 0 0 0 4.90E+08 4.06E+08 - - - 0.7347 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.18681.18681.2 0.0329 16-Sep K.ALLSALELK.K sp|P49454|CENPF_HUMAN 1 956.5906 1.13 51042 18681 2 956.591923 479.3026 Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3 6.05 3588 - 608240 - - - 1.3485 - 1.645 0.241 - 179.2 1 2 0 0.0013 9 0 0 0 4.17E+06 3.70E+06 - - - 2.2606 1 230117_WJC_METTL3_WT_vs_EV_F06.18682.18682.2 1.72E-05 20-Nov K.FLEMC[160.03]NDLLAR.V "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1380.653 11.96 51043 18682 2 1380.656259 691.3338 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.37 3588.2 - 532534 - - - 2.3663 - 2.218 0.532 - 430.3 1 2 0 0.0033 11 0 0 0 2.82E+07 2.36E+06 - - - 5.1243 1 230117_WJC_METTL3_WT_vs_EV_F06.18685.18685.2 6.69E-08 13/26 K.IVIPNEESVVIYYK[136.11].L sp|P42285|MTREX_HUMAN 1 1672.9167 0.6 51046 18685 2 1672.92015 837.4656 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.53 3588.6 - 207158 - - - 2.0473 - 2.358 0.585 - 427.8 1 2 0 0.0034 14 0 0 0 1.23E+06 2.07E+06 - - - 5.5134 1 230117_WJC_METTL3_WT_vs_EV_F06.18686.18686.2 0.00108 26-Dec K.YILVTGGVISGIGK.G "sp|P17812|PYRG1_HUMAN,sp|Q9NRF8|PYRG2_HUMAN,tr|A0A3B3ITH9|A0A3B3ITH9_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 7 1375.8075 2.18 51047 18686 2 1375.806052 688.911 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 8.59 3588.7 - 181646 - - - -1.0539 - 2.381 0.491 - 285.3 1 2 0 -0.0014 14 0 0 0 4.58E+06 2.10E+06 - - - 4.8441 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18691.18691.2 0.000363 14-Oct R.FLIQNVLR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1001.6022 1.46 51050 18691 2 1001.603491 501.8084 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.75 3589.2 - 3.80E+06 - - - 1.2879 - 2.085 0.323 - 474.8 1 2 0 0.0013 8 0 0 0 1.29E+08 8.82E+07 - - - 3.6423 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18693.18693.2 0.00113 18-Oct K.LYGEFADPFK.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1185.5706 2.03 51052 18693 2 1185.572947 593.7926 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3589.4 - 540996 - - - 1.9577 - 1.748 0.492 - 260.6 1 2 0 0.0023 10 0 0 0 1.73E+07 8.54E+06 - - - 4.233 0.9938 230117_WJC_METTL3_WT_vs_EV_F06.18703.18703.2 0.0698 20-Jun K.YLLDSC[160.03]APLLR[166.11].Y sp|Q92616|GCN1_HUMAN 1 1329.699 1.1 51060 18703 2 1329.698037 665.8568 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.83 3590.5 - 517919 - - - -0.7453 - 1.173 0.269 - 104.7 1 2 0 -0.001 11 0 0 0 9.10E+06 8.30E+06 - - - 1.4592 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.18709.18709.2 0.0255 20-Aug K.YLLDSC[160.03]APLLR.Y sp|Q92616|GCN1_HUMAN 1 1319.6908 1.1 51064 18709 2 1319.690697 660.8527 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.83 3591.3 - 356547 - - - -0.0462 - 1.718 0.3 - 189.4 1 2 0 -0.0001 11 0 0 0 9.10E+06 8.30E+06 - - - 2.7207 0.9845 230117_WJC_METTL3_WT_vs_EV_F06.18710.18710.2 1.88 12-Jul R.NLPFLIK[136.11].K sp|Q86TB9|PATL1_HUMAN 1 851.536 1.28 51065 18710 2 851.537523 426.7753 Protein PAT1 homolog 1 OS=Homo sapiens OX=9606 GN=PATL1 PE=1 SV=2 8.75 3591.4 - 643570 - - - 1.7592 - 1.169 0.09 - 153.4 1 2 0 0.0015 7 0 0 0 1.71E+07 1.33E+07 - - - 0.2 1 230117_WJC_METTL3_WT_vs_EV_F06.18711.18711.2 4.48E-05 18-Dec R.FEELC[160.03]SDLFR.S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1314.5914 19.28 51066 18711 2 1314.595002 658.303 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.14 3591.5 - 497547 - - - 2.7111 - 2.271 0.501 - 566.4 1 2 0 0.0036 10 0 0 0 9.34E+06 4.84E+05 - - - 5.0298 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.18712.18712.2 0.0223 18-Sep K.LYGEFADPFK[136.11].L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1193.5848 2.03 51067 18712 2 1193.589423 597.7997 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3591.6 - 335294 - - - 3.8514 - 1.434 0.348 - 188.5 1 2 0 0.0046 10 0 0 0 1.73E+07 8.54E+06 - - - 2.6161 1 230117_WJC_METTL3_WT_vs_EV_F06.18716.18716.2 6.39E-07 15/26 R.ALMGSPQLVAAVVR.T "sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9J826|C9J826_HUMAN" 5 1410.8017 999 51071 18716 2 1410.805324 706.4081 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 9.79 3592.1 - 186266 - - - 2.5652 - 2.82 0.532 - 655.5 1 2 0 0.0036 14 0 0 0 1.67E+07 0.00E+00 - - - 5.5709 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18721.18721.2 0.0198 16-Jul R.LQYLIDLGR.V "sp|Q9P015|RM15_HUMAN,tr|E5RHF4|E5RHF4_HUMAN,tr|E5RIZ4|E5RIZ4_HUMAN" 3 1089.6182 1.24 51074 18721 2 1089.619616 545.8164 "39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1" 5.84 3592.7 - 708549 - - - 1.2582 - 1.774 0.364 - 141.9 1 2 0 0.0014 9 0 0 0 1.80E+07 1.45E+07 - - - 3.3875 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18724.18724.2 0.000381 16-Jul K.LFTTMELMR.W sp|O00232|PSD12_HUMAN 1 1140.5671 1.64 51077 18724 2 1140.569077 571.2908 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 6 3592.9 - 1.14E+06 - - - 1.7009 - 1.66 0.439 - 162.2 1 2 0 0.0019 9 0 0 0 1.50E+07 9.17E+06 - - - 3.7491 0.9901 230117_WJC_METTL3_WT_vs_EV_F06.18725.18725.2 3.79 12-Jul R.WFEAFVK.R "sp|Q99543|DNJC2_HUMAN,tr|F2Z3H0|F2Z3H0_HUMAN,tr|H7C3L7|H7C3L7_HUMAN,tr|F2Z3N9|F2Z3N9_HUMAN" 4 925.4698 0.63 51078 18725 2 925.471766 463.7422 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 6 3592.9 - 628063 - - - 2.1351 - 1.228 0.121 - 115.9 1 2 0 0.002 7 0 0 0 1.03E+07 1.65E+07 - - - 0.5849 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18727.18727.2 1.94E-05 24-Dec R.LIEETISIAMATK[136.11].E "sp|O95249|GOSR1_HUMAN,tr|E9PCW1|E9PCW1_HUMAN,tr|G5E9T8|G5E9T8_HUMAN" 3 1426.7833 0.56 51080 18727 2 1426.785129 714.3989 Golgi SNAP receptor complex member 1 OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 4.53 3593.2 - 95816.4 - - - 1.3043 - 2.242 0.354 - 326.4 1 2 0 0.0019 13 0 0 0 2.07E+06 3.71E+06 - - - 3.7272 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.18734.18734.2 0.0005 18-Nov R.IPDEIIDMVK[136.11].E "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1179.6301 2.07 51085 18734 2 1179.635186 590.8223 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 4.03 3593.9 - 827716 - - - 4.3437 - 1.83 0.402 - 325.4 1 2 0 0.0051 10 0 0 0 4.44E+07 2.14E+07 - - - 3.6954 0.9906 230117_WJC_METTL3_WT_vs_EV_F06.18736.18736.2 0.00156 14-Jul K.FEFLGINR.Q sp|Q8N3X1|FNBP4_HUMAN 1 994.5236 1.12 51087 18736 2 994.52089 498.2691 Formin-binding protein 4 OS=Homo sapiens OX=9606 GN=FNBP4 PE=1 SV=3 6 3594.1 - 713863 - - - -2.741 - 1.636 0.232 - 160.7 1 2 0 -0.0027 8 0 0 0 8.57E+06 7.67E+06 - - - 2.2383 0.9959 230117_WJC_METTL3_WT_vs_EV_F06.18739.18739.2 0.000604 20-Sep R.LGYISVVDTLK.V "sp|Q01484|ANK2_HUMAN,sp|Q12955|ANK3_HUMAN,tr|A0A5F9ZH99|A0A5F9ZH99_HUMAN,tr|A0A5F9ZHE2|A0A5F9ZHE2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHL3|A0A5F9ZHL3_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZH03|A0A5F9ZH03_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHT8|A0A5F9ZHT8_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZH10|A0A5F9ZH10_HUMAN,tr|A0A5F9ZI41|A0A5F9ZI41_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZHT4|A0A5F9ZHT4_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI08|A0A5F9ZI08_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZI16|A0A5F9ZI16_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZH17|A0A5F9ZH17_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|E9PCH6|E9PCH6_HUMAN,tr|A0A5F9ZHQ3|A0A5F9ZHQ3_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZI36|A0A5F9ZI36_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|A0A5F9ZHN0|A0A5F9ZHN0_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZH18|A0A5F9ZH18_HUMAN,tr|A0A5F9ZHF7|A0A5F9ZHF7_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZI46|A0A5F9ZI46_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A669KB19|A0A669KB19_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 70 1206.686 999 51090 18739 2 1206.693025 604.3503 Ankyrin-2 OS=Homo sapiens OX=9606 GN=ANK2 PE=1 SV=4 5.83 3594.4 - 404786 - - - 5.83 - 1.773 0.45 - 169.7 1 2 0 0.007 11 0 0 0 2.96E+06 0.00E+00 - - - 3.9117 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18741.18741.2 0.000136 16-Sep R.SPTWFGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1059.5502 0.89 51091 18741 2 1059.552258 530.7824 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3594.6 - 1.23E+07 - - - 1.9754 - 1.906 0.379 - 416.3 1 2 0 0.0021 9 0 0 0 2.21E+08 2.48E+08 - - - 3.7057 0.9923 230117_WJC_METTL3_WT_vs_EV_F06.18750.18750.2 0.115 16-Jul K.LFTTMELMR[166.11].W sp|O00232|PSD12_HUMAN 1 1150.5754 1.64 51098 18750 2 1150.58027 576.295 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 6 3595.7 - 563137 - - - 4.2266 - 1.522 0.205 - 105.9 1 2 0 0.0049 9 0 0 0 1.50E+07 9.17E+06 - - - 1.7688 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.18755.18755.2 0.199 16-Nov K.ELIEELIAK[136.11].S "sp|P78316|NOP14_HUMAN,tr|E9PFK5|E9PFK5_HUMAN" 2 1064.6209 0.76 51101 18755 2 1064.623666 533.3177 Nucleolar protein 14 OS=Homo sapiens OX=9606 GN=NOP14 PE=1 SV=3 4.25 3596.4 - 2.75E+06 - - - 2.6197 - 2.07 0.256 - 376 1 2 0 0.0028 9 0 0 0 2.97E+07 3.94E+07 - - - 3.0358 0.9924 230117_WJC_METTL3_WT_vs_EV_F06.18756.18756.2 0.21 12-Jul R.YILDYLR.D "sp|Q96CX2|KCD12_HUMAN,sp|Q68DU8|KCD16_HUMAN" 2 954.5175 1.64 51102 18756 2 954.52047 478.266 BTB\POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1 5.83 3596.6 - 770488 - - - 3.145 - 1.55 0.103 - 202.7 1 2 0 0.003 7 0 0 0 2.07E+07 1.26E+07 - - - 1.1895 1 230117_WJC_METTL3_WT_vs_EV_F06.18760.18760.2 0.00347 22-Dec K.IIATVLMTEDIK[136.11].L "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 1353.7669 0.37 51106 18760 2 1353.767299 677.8907 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 3597 - 317367 - - - 0.3029 - 2.4 0.474 - 374.1 1 2 0 0.0004 12 0 0 0 1.71E+06 4.57E+06 - - - 4.8453 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18762.18762.2 0.0121 20-Aug K.FLC[160.03]YLSQAGFR.V sp|Q7Z2T5|TRM1L_HUMAN 1 1360.6598 1.82 51108 18762 2 1360.660046 681.3372 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 8.22 3597.2 - 254978 - - - 0.1867 - 1.801 0.382 - 171.2 1 2 0 0.0003 11 0 0 0 9.93E+06 5.46E+06 - - - 3.454 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.18764.18764.2 0.00023 20-Sep K.FLC[160.03]YLSQAGFR[166.11].V sp|Q7Z2T5|TRM1L_HUMAN 1 1370.6681 1.82 51110 18764 2 1370.67363 686.3413 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 8.22 3597.5 - 131160 - - - 4.0623 - 1.883 0.509 - 316.4 1 2 0 0.0056 11 0 0 0 9.93E+06 5.46E+06 - - - 4.5108 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.18767.18767.2 0.00195 18-Aug R.YDLGGLVMVK.D sp|Q15274|NADC_HUMAN 1 1093.5842 0.41 51112 18767 2 1093.58847 547.7994 Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Homo sapiens OX=9606 GN=QPRT PE=1 SV=3 5.83 3597.9 - 661814 - - - 3.9348 - 1.673 0.442 - 154.3 1 2 0 0.0043 10 0 0 0 2.89E+07 7.04E+07 - - - 3.7407 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.18772.18772.2 0.22 14-Aug K.TVALWDLR.N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 972.5393 1.97 51116 18772 2 972.540433 487.2769 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3598.5 - 2.01E+06 - - - 1.2 - 1.462 0.311 - 235.9 1 2 0 0.0012 8 0 0 0 9.75E+08 4.95E+08 - - - 2.4832 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.18776.18776.2 0.0137 16-Oct R.ALVAVLLSR.T sp|Q92616|GCN1_HUMAN 1 940.607 1.07 51120 18776 2 940.607793 471.3108 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.79 3598.8 - 1.38E+06 - - - 0.8941 - 2.181 0.163 - 348.8 1 2 0 0.0008 9 0 0 0 9.93E+06 9.32E+06 - - - 2.5006 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.18777.18777.2 0.0159 14-Aug K.TVALWDLR[166.11].N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 982.5475 1.97 51121 18777 2 982.550007 492.281 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3599 - 1.32E+06 - - - 2.5149 - 1.638 0.33 - 185.6 1 2 0 0.0025 8 0 0 0 9.74E+08 4.95E+08 - - - 2.9659 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18778.18778.2 0.000748 13/20 K.IGDFGLVTSLK.N "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 3 1148.6441 104.26 51122 18778 2 1148.646701 575.3293 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 5.84 3599.1 - 1.27E+06 - - - 2.2426 - 2.498 0.276 - 377.7 1 2 0 0.0026 11 0 0 0 5.03E+07 4.83E+05 - - - 3.5553 0.9867 230117_WJC_METTL3_WT_vs_EV_F06.18779.18779.2 0.692 12-Jul R.YILDYLR[166.11].D "sp|Q96CX2|KCD12_HUMAN,sp|Q68DU8|KCD16_HUMAN" 2 964.5257 1.81 51123 18779 2 964.526984 483.2701 BTB\POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1 5.83 3599.2 - 1.22E+06 - - - 1.2918 - 1.369 0.032 - 199.8 1 2 0 0.0012 7 0 0 0 2.35E+07 1.30E+07 - - - 0.2721 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.18780.18780.2 0.0469 14-Aug K.GAFIQLLR[166.11].Q "sp|Q13823|NOG2_HUMAN,tr|H0YG10|H0YG10_HUMAN" 2 926.5577 1 51124 18780 2 926.557538 464.2861 Nucleolar GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=GNL2 PE=1 SV=1 9.75 3599.4 - 842583 - - - -0.1824 - 1.665 0.176 - 176.7 1 2 0 -0.0002 8 0 0 0 1.54E+07 1.54E+07 - - - 1.8785 0.9998 230117_WJC_METTL3_WT_vs_EV_F06.18783.18783.3 0.000344 13/40 R.ILVTLLHTLER.M sp|Q9BWD1|THIC_HUMAN 1 1306.7973 1.27 51127 18783 3 1306.797654 436.6064 "Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2" 6.75 3599.7 - 568730 - - - 0.2923 - 2.198 0.385 - 260.9 1 2 0 0.0004 11 0 0 0 1.03E+07 8.06E+06 - - - 5.0696 0.9928 230117_WJC_METTL3_WT_vs_EV_F06.18786.18786.2 0.27 12-Jul K.WMGIAFR.L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 879.4425 1.29 51130 18786 2 879.443034 440.7285 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.75 3600.1 - 509342 - - - 0.5742 - 1.183 0.166 - 139.6 1 2 0 0.0005 7 0 0 0 3.35E+07 2.60E+07 - - - 0.7994 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18792.18792.2 0.0374 16-Oct R.YLTVAAVFR.G "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 5 1038.5862 2.79 51135 18792 2 1038.586403 520.3004 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3600.7 - 4.31E+07 - - - 0.1801 - 2.113 0.418 - 359.5 1 2 0 0.0002 9 0 0 0 1.36E+09 4.88E+08 - - - 4.2926 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18793.18793.2 0.000487 18-Oct R.ILVATNLFGR.G "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 6 1102.6499 1.32 51136 18793 2 1102.649931 552.3322 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 9.75 3600.7 - 1.03E+07 - - - 0.0472 - 2.046 0.44 - 320.5 1 2 0 0.0001 10 0 0 0 5.00E+08 3.77E+08 - - - 4.2891 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.18794.18794.2 0.143 18-Sep K.AIAINTFLPK[136.11].N sp|Q92615|LAR4B_HUMAN 1 1094.6579 1.17 51137 18794 2 1094.657868 548.3362 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3600.8 - 7.89E+06 - - - -0.0576 - 1.797 0.268 - 221.7 2 2 0 -0.0001 10 0 0 0 2.09E+08 1.80E+08 - - - 2.522 1 230117_WJC_METTL3_WT_vs_EV_F06.18796.18796.2 7.40E-07 22-Sep K.FGEAIGMGFPVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1259.6464 0.97 51139 18796 2 1259.646615 630.8305 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3600.9 - 2.52E+06 - - - 0.1866 - 2.24 0.498 - 237.1 1 2 0 0.0002 12 0 0 0 2.33E+08 2.40E+08 - - - 4.8411 0.9496 230117_WJC_METTL3_WT_vs_EV_F06.18803.18803.2 0.078 12-Aug L.SGFLVWR.R "sp|Q9NP84|TNR12_HUMAN,sp|Q96T88|UHRF1_HUMAN,tr|I3L1J9|I3L1J9_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 6 863.4654 1.52 51146 18803 2 863.465421 432.74 Tumor necrosis factor receptor superfamily member 12A OS=Homo sapiens OX=9606 GN=TNFRSF12A PE=1 SV=1 9.47 3601.5 - 976095 - - - 0.0556 - 1.804 0.327 - 266.4 1 1 0 0 7 0 0 0 2.20E+07 1.45E+07 - - - 3.3257 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18808.18808.2 0.00126 20-Nov K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 0.93 51149 18808 2 1197.720711 599.8679 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3602.1 - 448782 - - - -0.4584 - 2.293 0.409 - 288.6 1 2 0 -0.0005 11 0 0 0 1.21E+09 1.30E+09 - - - 4.3067 1 230117_WJC_METTL3_WT_vs_EV_F06.18809.18809.2 1.01E-06 13/20 K.VANVSLLALYK.G sp|P62266|RS23_HUMAN 1 1189.7071 0.93 51150 18809 2 1189.708271 595.8608 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3602.3 - 206805 - - - 1.0179 - 2.777 0.46 - 832.3 1 2 0 0.0012 11 0 0 0 1.21E+09 1.30E+09 - - - 5.2012 0.9609 230117_WJC_METTL3_WT_vs_EV_F06.18811.18811.2 0.00801 14-Aug K.NSLESYAF.N "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 929.4131 - 51152 18811 2 929.413628 465.7138 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4 3602.4 - 2.04E+06 - - - 0.6079 - 1.33 0.469 - 169.2 1 1 0 0.0006 8 0 0 0 - - - - - 3.3649 0.9846 230117_WJC_METTL3_WT_vs_EV_F06.18814.18814.2 0.13 12-May R.GLFDSFR.R "sp|Q96IK1|BOD1_HUMAN,sp|Q8IYS8|BD1L2_HUMAN,tr|C9JNZ5|C9JNZ5_HUMAN" 3 840.413 2.63 51155 18814 2 840.413744 421.2138 Biorientation of chromosomes in cell division protein 1 OS=Homo sapiens OX=9606 GN=BOD1 PE=1 SV=2 5.84 3602.7 - 235761 - - - 0.8817 - 0.997 0.159 - 95.7 1 2 0 0.0007 7 0 0 0 1.23E+07 4.66E+06 - - - 0.2056 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.18815.18815.2 0.214 16-Nov R.LDALLAELR[166.11].A sp|Q96L58|B3GT6_HUMAN 1 1022.6 1.02 51156 18815 2 1022.59924 512.3073 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 4.37 3602.9 - 644790 - - - -0.71 - 2.26 0.201 - 312.9 1 2 0 -0.0007 9 0 0 0 2.44E+07 2.39E+07 - - - 2.8843 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18819.18819.2 0.0082 16-Aug R.YLTVAAVFR[166.11].G "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 5 1048.5945 2.79 51159 18819 2 1048.595495 525.3045 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3603.3 - 2.54E+07 - - - 0.9622 - 1.812 0.338 - 201.9 1 2 0 0.001 9 0 0 0 1.36E+09 4.88E+08 - - - 3.2569 0.9855 230117_WJC_METTL3_WT_vs_EV_F06.18820.18820.2 0.181 12-Jun K.WMGIAFR[166.11].L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 889.4508 1.28 51160 18820 2 889.450828 445.7327 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.75 3603.3 - 2.33E+06 - - - 0.0326 - 1.071 0.164 - 149.9 1 2 0 0 7 0 0 0 3.29E+07 2.57E+07 - - - 0.4696 0.999 230117_WJC_METTL3_WT_vs_EV_F06.18833.18833.2 0.0061 16-Oct R.LDALLAELR.A sp|Q96L58|B3GT6_HUMAN 1 1012.5917 0.99 51168 18833 2 1012.591726 507.3031 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 4.37 3604.8 - 1.50E+06 - - - 0.0296 - 2.372 0.177 - 361.5 1 2 0 0 9 0 0 0 2.36E+07 2.38E+07 - - - 2.8471 0.9932 230117_WJC_METTL3_WT_vs_EV_F06.18834.18834.2 0.00435 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 4.64 51169 18834 2 1006.576098 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3604.9 - 551650 - - - 6.1595 - 1.631 0.399 - 227.1 1 2 0 0.0062 9 0 0 0 1.49E+07 3.22E+06 - - - 3.4013 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18836.18836.2 0.000672 14-Aug R.AEWLLAVR[166.11].S sp|Q9NRN7|ADPPT_HUMAN 1 966.5526 3.24 51171 18836 2 966.553941 484.2836 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2 6.05 3605.2 - 851742 - - - 1.3657 - 1.725 0.353 - 312.6 1 2 0 0.0013 8 0 0 0 4.03E+07 1.24E+07 - - - 3.2922 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.18837.18837.2 2.18 14-Jul R.ILLTLGIR.L "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 897.6011 1.21 51172 18837 2 897.601537 449.8078 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 9.75 3605.3 - 556051 - - - 0.4445 - 1.538 0.322 - 145.8 1 2 0 0.0004 8 0 0 0 8.21E+06 6.79E+06 - - - 2.7175 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.18838.18838.2 0.148 18-Sep K.LLALGLVAER.R sp|Q9UNS1|TIM_HUMAN 1 1053.6546 2.33 51173 18838 2 1053.655045 527.8346 Protein timeless homolog OS=Homo sapiens OX=9606 GN=TIMELESS PE=1 SV=2 6 3605.4 - 396694 - - - 0.3939 - 1.73 0.212 - 204.8 1 2 0 0.0004 10 0 0 0 6.42E+06 2.76E+06 - - - 2.1367 0.9934 230117_WJC_METTL3_WT_vs_EV_F06.18839.18839.2 0.000761 24-Aug K.AEPLLGAPGELLK.Q sp|P17482|HXB9_HUMAN 1 1306.7497 2.88 51174 18839 2 1306.745392 654.3821 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 3605.6 - 292354 - - - -3.2608 - 1.681 0.374 - 128 2 2 0 -0.0043 13 0 0 0 2.53E+07 8.77E+06 - - - 3.0006 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.18845.18845.2 0.00988 18-Oct R.FLLQDTVELR.E "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1232.6765 1.7 51178 18845 2 1232.675052 617.3455 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3606.3 - 6.23E+06 - - - -1.1649 - 2.214 0.331 - 390.7 1 2 0 -0.0014 10 0 0 0 1.63E+08 9.61E+07 - - - 3.7038 1 230117_WJC_METTL3_WT_vs_EV_F06.18847.18847.2 7.66E-06 22-Dec K.SLAMEMVLTGDR.L sp|P30084|ECHM_HUMAN 1 1321.637 1.31 51180 18847 2 1321.637671 661.8258 "Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4" 4.37 3606.6 - 422704 - - - 0.5017 - 2.518 0.481 - 237.6 1 2 0 0.0007 12 0 0 0 8.28E+06 6.32E+06 - - - 5.0233 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18848.18848.2 0.025 22-Nov K.SLAMEMVLTGDR[166.11].L sp|P30084|ECHM_HUMAN 1 1331.6453 1.31 51181 18848 2 1331.644523 666.8299 "Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4" 4.37 3606.7 - 363880 - - - -0.567 - 2.153 0.401 - 347.9 1 2 0 -0.0008 12 0 0 0 8.28E+06 6.32E+06 - - - 4.0203 1 230117_WJC_METTL3_WT_vs_EV_F06.18853.18853.2 1.84E-05 18-Oct R.FEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1252.6088 11.63 51184 18853 2 1252.608116 627.3117 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3607.4 - 4.16E+06 - - - -0.5477 - 2.112 0.562 - 347.1 1 2 0 -0.0007 10 0 0 0 9.39E+08 8.08E+07 - - - 5.2786 0.9131 230117_WJC_METTL3_WT_vs_EV_F06.18855.18855.2 15.4 12-Jun R.VLFLIPK.N "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q5JV98|Q5JV98_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|H0Y630|H0Y630_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 13 828.5473 2.25 51186 18855 2 828.546782 415.2809 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 8.72 3607.6 - 873709 - - - -0.6397 - 1.14 0.026 - 131.2 2 2 0 -0.0005 7 0 0 0 3.98E+07 1.77E+07 - - - -0.4864 0.9836 230117_WJC_METTL3_WT_vs_EV_F06.18857.18857.2 0.313 12-May R.VLFLIPK[136.11].N "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q5JV98|Q5JV98_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|H0Y630|H0Y630_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 13 836.5615 2.25 51188 18857 2 836.560543 419.288 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 8.72 3607.9 - 409672 - - - -1.1583 - 1.115 0.205 - 55.1 1 2 0 -0.001 7 0 0 0 3.98E+07 1.77E+07 - - - 0.8997 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.18858.18858.2 0.0753 18-Sep R.FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1262.6171 11.63 51189 18858 2 1262.620599 632.3158 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3608 - 312338 - - - 2.7934 - 1.961 0.336 - 268.6 1 2 0 0.0035 10 0 0 0 9.39E+08 8.08E+07 - - - 3.4014 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.18862.18862.2 0.0139 14-Jun K.VFGFDSFK.T "sp|O94762|RECQ5_HUMAN,tr|J3KTQ2|J3KTQ2_HUMAN" 2 945.4596 0.39 51191 18862 2 945.459518 473.7371 ATP-dependent DNA helicase Q5 OS=Homo sapiens OX=9606 GN=RECQL5 PE=1 SV=2 5.81 3608.6 - 707619 - - - -0.1068 - 1.251 0.386 - 93.3 1 2 0 -0.0001 8 0 0 0 6.86E+06 1.74E+07 - - - 2.5674 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.18867.18867.2 0.753 16-Sep R.VEFILEQMR.L sp|O00232|PSD12_HUMAN 1 1163.6009 1.84 51196 18867 2 1163.598368 582.8077 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.53 3609.1 - 1.05E+06 - - - -2.1588 - 2.046 0.395 - 397.6 1 2 0 -0.0025 9 0 0 0 1.41E+07 7.71E+06 - - - 4.0288 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18868.18868.2 0.00154 18-Dec K.IEVIEIMTDR[166.11].G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1227.6408 0.9 51197 18868 2 1227.640265 614.8277 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3609.2 - 981362 - - - -0.4716 - 2.311 0.341 - 590.9 1 2 0 -0.0006 10 0 0 0 1.66E+08 1.85E+08 - - - 3.8977 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18885.18885.2 0.00516 13/18 K.IEVIEIMTDR.G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1217.6326 0.9 51210 18885 2 1217.63195 609.8236 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3611.3 - 2.01E+06 - - - -0.5125 - 2.471 0.364 - 718.2 1 2 0 -0.0006 10 0 0 0 1.66E+08 1.85E+08 - - - 4.2544 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.18894.18894.2 0.00147 20-Nov K.TPPPVLIFAEK.K sp|Q9UJV9|DDX41_HUMAN 1 1210.6962 1.62 51217 18894 2 1210.6959 606.3554 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3612.5 - 1.05E+06 - - - -0.2156 - 1.763 0.316 - 308 1 2 0 -0.0003 11 0 0 0 1.18E+08 7.26E+07 - - - 2.9088 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.18896.18896.2 0.00249 24-Nov K.AEPLLGAPGELLK[136.11].Q sp|P17482|HXB9_HUMAN 1 1314.7639 2.88 51219 18896 2 1314.761975 658.3892 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 3612.7 - 777695 - - - -1.4284 - 1.766 0.334 - 216.6 1 2 0 -0.0019 13 0 0 0 2.53E+07 8.77E+06 - - - 2.967 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.18897.18897.2 0.000465 20-Oct R.LAVDLSEVVIK.W "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1184.7016 0.21 51220 18897 2 1184.701353 593.3581 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.37 3612.8 - 261035 - - - -0.2423 - 1.873 0.342 - 206.8 1 2 0 -0.0003 11 0 0 0 1.57E+07 7.55E+07 - - - 3.2646 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18902.18902.2 0.0546 20-Oct R.LLDMDGIIVEK.Q sp|Q14152|EIF3A_HUMAN 1 1244.6686 0.95 51223 18902 2 1244.67038 623.3416 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.03 3613.4 - 2.62E+06 - - - 1.41 - 2.208 0.313 - 185.4 1 2 0 0.0018 11 0 0 0 6.19E+07 6.51E+07 - - - 3.495 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18919.18919.2 0.00318 20-Nov R.IGFVGFPSVGK[136.11].S sp|Q9Y295|DRG1_HUMAN 1 1114.6266 1.76 51237 18919 2 1114.629489 558.3206 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 8.75 3615.2 - 2.10E+06 - - - 2.5641 - 1.946 0.381 - 289.3 1 2 0 0.0029 11 0 0 0 7.84E+07 4.46E+07 - - - 3.6552 1 230117_WJC_METTL3_WT_vs_EV_F06.18920.18920.2 0.000181 20-Nov K.FAVALLDDSVR.V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1204.6452 2.17 51238 18920 2 1204.638834 603.3299 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 4.21 3615.3 - 715163 - - - -5.2746 - 2.443 0.491 - 385.8 1 2 0 -0.0064 11 0 0 0 3.39E+07 1.56E+07 - - - 5.0819 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18921.18921.2 0.000206 13/20 R.IGFVGFPSVGK.S sp|Q9Y295|DRG1_HUMAN 1 1106.6124 1.76 51239 18921 2 1106.613898 554.3135 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 8.75 3615.3 - 3.08E+06 - - - 1.3257 - 2.391 0.43 - 437.2 1 2 0 0.0015 11 0 0 0 7.84E+07 4.46E+07 - - - 4.5747 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.18931.18931.2 0.0826 16-Jul K.GFGFVSFER[166.11].H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1054.5112 0.95 51247 18931 2 1054.51478 528.2629 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3616.5 - 589392 - - - 3.4414 - 1.516 0.329 - 149.1 1 2 0 0.0036 9 0 0 0 3.95E+08 4.15E+08 - - - 2.6736 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.18932.18932.2 0.00451 12-Jun K.DYVDLFR.H sp|P78527|PRKDC_HUMAN 1 926.4498 0.43 51248 18932 2 926.450926 464.2322 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.21 3616.6 - 716033 - - - 1.2348 - 1.237 0.4 - 169.5 1 2 0 0.0011 7 0 0 0 1.97E+07 4.57E+07 - - - 2.669 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.18933.18933.2 0.0801 14-Aug R.DLTDYLMK[136.11].L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 1005.4932 1.1 51249 18933 2 1005.495068 503.7539 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3616.7 - 718633 - - - 1.824 - 1.403 0.263 - 199.1 1 2 0 0.0018 8 0 0 0 6.49E+07 5.87E+07 - - - 2.0042 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18934.18934.2 0.00015 20-Sep R.YLLEQDFPGMR.L "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN" 2 1367.6544 2.48 51250 18934 2 1367.65627 684.8345 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.37 3616.8 - 288186 - - - 1.3878 - 2.064 0.303 - 269.2 1 2 0 0.0019 11 0 0 0 3.50E+06 1.41E+06 - - - 3.2387 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.18935.18935.2 0.244 14-Jun R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 1.13 51251 18935 2 898.524104 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 3617 - 282211 - - - 0.5431 - 1.404 0.215 - 81.7 1 2 0 0.0005 8 0 0 0 1.16E+07 1.02E+07 - - - 1.6522 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.18938.18938.2 0.0135 14-Jun R.DLTDYLMK.L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 997.479 1.11 51252 18938 2 997.481004 499.7468 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3617.4 - 1.84E+06 - - - 1.975 - 1.316 0.326 - 102.6 1 2 0 0.002 8 0 0 0 6.50E+07 5.87E+07 - - - 2.2764 0.9961 230117_WJC_METTL3_WT_vs_EV_F06.18940.18940.2 3.52 14-May R.ITNWLVLK.N "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN,tr|H3BRT3|H3BRT3_HUMAN" 3 985.5961 2.07 51254 18940 2 985.597016 493.8053 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 8.75 3617.5 - 810070 - - - 0.9771 - 1.097 0.253 - 54.1 1 2 0 0.001 8 0 0 0 8.67E+06 4.19E+06 - - - 1.1886 0.9933 230117_WJC_METTL3_WT_vs_EV_F06.18944.18944.2 0.00309 20-Oct R.LAQPYVGVFLK.R "sp|P36776|LONM_HUMAN,tr|K7EQF8|K7EQF8_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN" 4 1233.7121 0.84 51256 18944 2 1233.718592 617.8633 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 8.59 3618 - 386029 - - - 5.2257 - 1.549 0.32 - 194.1 1 2 0 0.0064 11 0 0 0 4.93E+06 5.88E+06 - - - 2.5863 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18946.18946.2 3.86E-05 16-Oct K.GFGFVSFER.H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1044.5029 0.95 51258 18946 2 1044.504716 523.2587 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3618.1 - 2.78E+06 - - - 1.7568 - 1.83 0.463 - 414.2 1 2 0 0.0018 9 0 0 0 3.95E+08 4.15E+08 - - - 4.2085 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18947.18947.2 1.05E-06 15/22 K.IIENELEGFGIR.L sp|Q9Y295|DRG1_HUMAN 1 1388.73 1.21 51259 18947 2 1388.733198 695.3723 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3618.3 - 849196 - - - 2.3172 - 2.338 0.421 - 753 1 2 0 0.0032 12 0 0 0 1.45E+07 1.20E+07 - - - 4.3841 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.18949.18949.2 0.00261 22-Nov K.IIENELEGFGIR[166.11].L sp|Q9Y295|DRG1_HUMAN 1 1398.7383 1.21 51261 18949 2 1398.737386 700.3764 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3618.5 - 600207 - - - -0.6177 - 2.211 0.445 - 301.5 1 2 0 -0.0009 12 0 0 0 1.45E+07 1.20E+07 - - - 4.4152 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18950.18950.2 0.0165 16-Aug K.GLDFALLQK[136.11].V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1011.5844 1.2 51262 18950 2 1011.585266 506.7995 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3618.7 - 505258 - - - 0.8244 - 1.817 0.411 - 153 1 2 0 0.0008 9 0 0 0 4.83E+07 4.03E+07 - - - 3.8041 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.18951.18951.2 0.00282 16-Aug K.ILVTPWDYR.L sp|Q8TF46|DI3L1_HUMAN 1 1161.6182 0.37 51263 18951 2 1161.621641 581.8164 DIS3-like exonuclease 1 OS=Homo sapiens OX=9606 GN=DIS3L PE=1 SV=2 5.84 3618.8 - 393780 - - - 2.9235 - 1.733 0.369 - 213.3 1 2 0 0.0034 9 0 0 0 3.44E+06 9.42E+06 - - - 3.3561 0.9955 230117_WJC_METTL3_WT_vs_EV_F06.18955.18955.2 0.622 18-Jun K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.21 51266 18955 2 1086.645743 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3619.3 - 2.36E+06 - - - 1.8516 - 1.449 0.138 - 95.1 1 2 0 0.002 10 0 0 0 4.90E+08 4.06E+08 - - - 1.0949 0.958 230117_WJC_METTL3_WT_vs_EV_F06.18957.18957.2 0.775 20-Jul K.TPPPVLIFAEK[136.11].K sp|Q9UJV9|DDX41_HUMAN 1 1218.7104 1.6 51268 18957 2 1218.712283 610.3625 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3619.4 - 2.39E+06 - - - 1.5771 - 0.918 0.097 - 104.6 1 2 0 0.0019 11 0 0 0 1.16E+08 7.26E+07 - - - -0.4746 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18958.18958.2 0.00294 20-Oct R.ILLLGLDNAGK.T "sp|P36405|ARL3_HUMAN,sp|Q13795|ARFRP_HUMAN" 2 1125.6758 1.37 51269 18958 2 1125.678572 563.8452 ADP-ribosylation factor-like protein 3 OS=Homo sapiens OX=9606 GN=ARL3 PE=1 SV=2 5.84 3619.4 - 278729 - - - 2.4981 - 2.024 0.401 - 246.7 1 2 0 0.0028 11 0 0 0 2.24E+07 1.63E+07 - - - 3.9093 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.18960.18960.2 0.00108 16-Jul R.SPTWFGIPR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1069.5584 1.01 51270 18960 2 1069.560389 535.7865 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3619.6 - 1.04E+06 - - - 1.8269 - 1.578 0.234 - 182.8 1 2 0 0.002 9 0 0 0 3.22E+08 3.19E+08 - - - 2.0884 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18962.18962.2 0.105 18-Dec R.TLDLPIYVTR.V "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 5 1189.6707 1.09 51271 18962 2 1189.672601 595.8426 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.5 3619.9 - 5.02E+06 - - - 1.6198 - 2 0.332 - 468 1 2 0 0.0019 10 0 0 0 2.56E+07 2.36E+07 - - - 3.4273 1 230117_WJC_METTL3_WT_vs_EV_F06.18964.18964.2 1.99E-06 13/22 K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 2.1 51273 18964 2 1263.693145 632.853 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3620.1 - 2.43E+06 - - - 1.3682 - 2.246 0.478 - 423.4 1 2 0 0.0017 12 0 0 0 2.68E+07 1.28E+07 - - - 4.7 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.18969.18969.2 0.0152 20-Oct R.LMMDPLTGLNR[166.11].G "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1269.6449 1.25 51278 18969 2 1269.642441 635.8297 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.84 3620.7 - 412491 - - - -1.9242 - 1.847 0.427 - 323.1 1 2 0 -0.0024 11 0 0 0 2.45E+07 1.97E+07 - - - 3.8539 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18970.18970.2 0.0413 24-Sep R.LDYLGVSYGLTPR[166.11].L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1462.7695 0.85 51279 18970 2 1462.769927 732.3921 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.83 3620.8 - 315776 - - - 0.2577 - 1.98 0.382 - 132.7 1 2 0 0.0004 13 0 0 0 6.23E+06 7.33E+06 - - - 3.6155 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18974.18974.2 0.000255 24-Dec R.ILLAEVPTMAVEK[136.11].V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1420.8091 6.06 51283 18974 2 1420.810018 711.4118 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3621.4 - 246705 - - - 0.6539 - 2.207 0.408 - 371.9 1 2 0 0.0009 13 0 0 0 4.56E+07 7.52E+06 - - - 4.0859 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18980.18980.2 7.42E-06 22-Nov K.NIEDVIAQGIGK.L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1255.6772 2.11 51287 18980 2 1255.680037 628.8459 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3622.1 - 1.87E+06 - - - 2.2466 - 2.058 0.473 - 254.7 1 2 0 0.0028 12 0 0 0 2.69E+07 1.28E+07 - - - 4.4327 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18981.18981.2 0.00464 16-Sep K.LTQILSYLR.Q sp|Q13123|RED_HUMAN 1 1105.6495 1.44 51288 18981 2 1105.652314 553.832 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3622.1 - 2.24E+06 - - - 2.5044 - 1.932 0.39 - 293.5 1 2 0 0.0028 9 0 0 0 9.29E+07 6.44E+07 - - - 3.8259 0.9923 230117_WJC_METTL3_WT_vs_EV_F06.18982.18982.2 0.468 12-Apr R.EYLYFLK.H sp|Q8N1N4|K2C78_HUMAN 1 974.5113 16.97 51289 18982 2 974.512196 488.2629 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 6.1 3622.1 - 2.57E+06 - - - 0.8989 - 1.04 0.206 - 68.7 1 2 0 0.0009 7 0 0 0 3.45E+07 2.03E+06 - - - 0.6865 0.9947 230117_WJC_METTL3_WT_vs_EV_F06.18984.18984.2 0.156 16-Nov K.LTQILSYLR[166.11].Q sp|Q13123|RED_HUMAN 1 1115.6578 1.44 51291 18984 2 1115.665095 558.8362 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3622.3 - 1.85E+06 - - - 6.5253 - 2.236 0.408 - 563.5 1 2 0 0.0073 9 0 0 0 9.26E+07 6.43E+07 - - - 4.3802 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.18985.18985.2 0.00317 14-Sep K.IDILTELR[166.11].D "sp|O00139|KIF2A_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 981.5734 1.19 51292 18985 2 981.574661 491.794 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.37 3622.3 - 1.80E+06 - - - 1.2674 - 2.03 0.316 - 278.8 1 2 0 0.0012 8 0 0 0 7.20E+07 6.05E+07 - - - 3.51 1 230117_WJC_METTL3_WT_vs_EV_F06.18986.18986.2 2.47E-06 16/20 M.PPYTVVYFPVR[166.11].G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1346.7262 1.15 51293 18986 2 1346.730696 674.3704 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3622.4 - 648779 - - - 3.3169 - 3.085 0.508 - 972.7 1 2 0 0.0045 11 0 0 0 5.41E+07 4.71E+07 - - - 5.8393 1 230117_WJC_METTL3_WT_vs_EV_F06.18988.18988.2 2.54E-06 18-Oct K.C[160.03]LEEFELLGK.A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1236.606 0.96 51295 18988 2 1236.609374 619.3103 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3622.7 - 367868 - - - 2.7082 - 2.003 0.542 - 294 1 2 0 0.0033 10 0 0 0 1.02E+07 1.05E+07 - - - 4.9821 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.18989.18989.2 8.07E-05 18-Oct K.TWLLADEGLR.Q sp|Q9BWH6|RPAP1_HUMAN 1 1172.619 1.07 51296 18989 2 1172.622845 587.3168 RNA polymerase II-associated protein 1 OS=Homo sapiens OX=9606 GN=RPAP1 PE=1 SV=3 4.37 3622.8 - 325189 - - - 3.302 - 1.82 0.409 - 272.4 1 2 0 0.0039 10 0 0 0 1.71E+06 1.59E+06 - - - 3.7322 1 230117_WJC_METTL3_WT_vs_EV_F06.18992.18992.2 5.08E-05 14/24 R.ILLAEVPTMAVEK.V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1412.7949 6.07 51298 18992 2 1412.796969 707.4047 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3623.2 - 1.55E+06 - - - 1.4723 - 2.509 0.511 - 595.6 1 2 0 0.0021 13 0 0 0 4.57E+07 7.52E+06 - - - 5.1755 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18994.18994.2 0.0059 16-Oct K.GLDFALLQK.V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1003.5702 1.19 51300 18994 2 1003.571815 502.7924 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3623.3 - 3.47E+06 - - - 1.5774 - 1.929 0.424 - 294.3 1 2 0 0.0016 9 0 0 0 4.86E+07 4.08E+07 - - - 4.0729 1 230117_WJC_METTL3_WT_vs_EV_F06.18995.18995.2 4.18E-07 16/20 M.PPYTVVYFPVR.G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1336.718 1.16 51301 18995 2 1336.720245 669.3663 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3623.5 - 594024 - - - 1.7102 - 3.015 0.561 - 1311.8 1 2 0 0.0023 11 0 0 0 5.41E+07 4.68E+07 - - - 6.1693 0.9866 230117_WJC_METTL3_WT_vs_EV_F06.18996.18996.2 0.635 12-Aug R.WLLELSK[136.11].K sp|P35573|GDE_HUMAN 1 895.5259 1.09 51302 18996 2 895.524317 448.7702 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 6 3623.6 - 482148 - - - -1.7163 - 1.486 0.141 - 204 1 2 0 -0.0015 7 0 0 0 1.62E+07 1.49E+07 - - - 1.337 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.18997.18997.2 0.000318 20-Oct R.LEPLVNDLTLR.L sp|Q70UQ0|IKIP_HUMAN 1 1281.7293 1.16 51303 18997 2 1281.732407 641.8719 Inhibitor of nuclear factor kappa-B kinase-interacting protein OS=Homo sapiens OX=9606 GN=IKBIP PE=1 SV=1 4.37 3623.7 - 259956 - - - 2.4615 - 1.987 0.394 - 292.9 1 2 0 0.0032 11 0 0 0 1.26E+07 1.09E+07 - - - 3.8076 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.18999.18999.2 6.74E-05 26-Oct K.LNLVDLAGSENIGR.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1469.7838 0.02 51305 18999 2 1469.786205 735.8992 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 3624 - 171083 - - - 1.6315 - 1.971 0.443 - 301.9 1 2 0 0.0024 14 0 0 0 1.40E+06 6.41E+07 - - - 4.015 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.19005.19005.2 0.00214 20-Aug R.TVPILFASTVR.R sp|Q6P1M0|S27A4_HUMAN 1 1202.7023 0.37 51309 19005 2 1202.707156 602.3584 Long-chain fatty acid transport protein 4 OS=Homo sapiens OX=9606 GN=SLC27A4 PE=1 SV=1 9.41 3624.7 - 984164 - - - 4.0301 - 1.603 0.409 - 180.5 1 2 0 0.0048 11 0 0 0 1.01E+07 2.70E+07 - - - 3.3369 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19006.19006.2 0.00021 18-Nov K.C[160.03]LEEFELLGK[136.11].A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1244.6202 0.96 51310 19006 2 1244.621096 623.3174 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3624.7 - 467887 - - - 0.6998 - 2.15 0.426 - 333.5 1 2 0 0.0009 10 0 0 0 1.02E+07 1.05E+07 - - - 4.3238 1 230117_WJC_METTL3_WT_vs_EV_F06.19007.19007.2 1.98E-06 18-Oct K.GIFLGDDEWR[166.11].E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1216.5752 1.7 51311 19007 2 1216.575659 609.2949 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3624.8 - 860774 - - - 0.3715 - 2.082 0.508 - 348.2 1 2 0 0.0005 10 0 0 0 1.89E+07 1.12E+07 - - - 4.8399 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.19014.19014.3 0.000963 Dec-36 R.DFLLK[136.11]PELLR[166.11].A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1260.7561 1.18 51316 19014 3 1260.757957 421.2593 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3625.6 - 2.66E+06 - - - 1.4896 - 2.306 0.485 - 175.2 1 2 0 0.0019 10 0 0 0 2.95E+07 2.51E+07 - - - 6.3868 1 230117_WJC_METTL3_WT_vs_EV_F06.19015.19015.2 6.52E-06 20-Dec K.MALDIEIATYR[166.11].K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1304.6674 1.43 51317 19015 2 1304.671315 653.341 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3625.7 - 1.51E+06 - - - 3.0061 - 2.74 0.497 - 682.1 1 2 0 0.0039 11 0 0 0 6.35E+07 4.45E+07 - - - 5.4374 1 230117_WJC_METTL3_WT_vs_EV_F06.19018.19018.2 1.47E-06 18-Oct K.GIFLGDDEWR.E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1206.5669 1.7 51320 19018 2 1206.57093 604.2907 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3626 - 2.02E+06 - - - 3.3094 - 2.134 0.502 - 345.3 1 2 0 0.004 10 0 0 0 1.89E+07 1.11E+07 - - - 4.8633 0.997 230117_WJC_METTL3_WT_vs_EV_F06.19019.19019.2 0.152 18-Aug K.LLLGDLAPVR.G sp|Q9NUQ8|ABCF3_HUMAN 1 1065.6546 3.24 51321 19019 2 1065.65739 533.8346 ATP-binding cassette sub-family F member 3 OS=Homo sapiens OX=9606 GN=ABCF3 PE=1 SV=2 5.84 3626.1 - 1.92E+06 - - - 2.59 - 1.715 0.156 - 155.5 1 2 0 0.0028 10 0 0 0 9.93E+06 3.06E+06 - - - 1.698 0.9933 230117_WJC_METTL3_WT_vs_EV_F06.19020.19020.2 0.00941 16-Oct R.LLIDEAILK[136.11].C "sp|P49591|SYSC_HUMAN,tr|Q5T5C7|Q5T5C7_HUMAN" 2 1034.6467 1.33 51322 19020 2 1034.651968 518.3306 "Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3" 4.37 3626.2 - 1.41E+06 - - - 5.0935 - 1.686 0.264 - 214.9 1 2 0 0.0053 9 0 0 0 1.19E+07 8.99E+06 - - - 2.5005 1 230117_WJC_METTL3_WT_vs_EV_F06.19022.19022.2 0.000182 18-Dec K.TIC[160.03]AEFAILR.M "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1192.6274 0.68 51324 19022 2 1192.632256 597.321 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.66 3626.5 - 1.07E+06 - - - 4.0474 - 2.093 0.517 - 426.4 1 2 0 0.0048 10 0 0 0 1.50E+07 2.20E+07 - - - 4.9197 0.9367 230117_WJC_METTL3_WT_vs_EV_F06.19024.19024.2 4.32 14-Jun R.VPNAEEIF.- "sp|Q9BW92|SYTM_HUMAN,tr|F6S7Q7|F6S7Q7_HUMAN,tr|U3KQG0|U3KQG0_HUMAN" 3 917.4494 - 51326 19024 2 917.45219 459.732 "Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1" 3.79 3626.7 - 1.36E+06 - - - 2.9887 - 0.992 0.082 - 99.2 1 2 0 0.0027 8 0 0 0 - - - - - -0.3784 0.985 230117_WJC_METTL3_WT_vs_EV_F06.19025.19025.2 0.000238 14-Sep K.LGTLFAFK[136.11].K sp|Q6F5E8|CARL2_HUMAN 1 903.5309 4.02 51327 19025 2 903.537551 452.7727 "Capping protein, Arp2\3 and myosin-I linker protein 2 OS=Homo sapiens OX=9606 GN=CARMIL2 PE=1 SV=2" 8.75 3626.8 - 631233 - - - 7.3168 - 1.827 0.324 - 169.1 1 2 0 0.0066 8 0 0 0 1.81E+07 4.49E+06 - - - 3.2496 0.9921 230117_WJC_METTL3_WT_vs_EV_F06.19030.19030.2 0.0461 24-Jun R.LLPPEDTQELIFK[136.11].D sp|O60287|NPA1P_HUMAN 1 1549.8483 -1 51332 19030 2 1549.853356 775.9314 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 4.14 3627.5 - 187408 - - - 3.2552 - 1.241 0.219 - 50.2 1 2 0 0.005 13 0 0 0 0.00E+00 0.00E+00 - - - 1.2111 0.9713 230117_WJC_METTL3_WT_vs_EV_F06.19032.19032.2 0.00145 Jul-34 K.SSGPTSLFAVTVAPPGAR.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1713.905 0.97 51334 19032 2 1713.918831 857.9598 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3627.7 - 123912 - - - 8.0792 - 1.682 0.341 - 132.6 1 2 0 0.0138 18 0 0 0 1.04E+06 1.08E+06 - - - 2.8337 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19036.19036.2 0.0111 14-Aug K.LLQQLFLK.A sp|Q9P287|BCCIP_HUMAN 1 1001.6274 1.34 51337 19036 2 1001.628351 501.821 BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1 8.75 3628.2 - 1.59E+06 - - - 0.9964 - 1.679 0.299 - 170.5 1 2 0 0.001 8 0 0 0 2.27E+07 1.69E+07 - - - 2.812 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19037.19037.2 0.00011 16-Oct K.ASSLISLLK.Q "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 930.575 2.26 51338 19037 2 930.575784 466.2948 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.8 3628.2 - 1.47E+06 - - - 0.8608 - 2.078 0.42 - 449.6 1 2 0 0.0008 9 0 0 0 3.35E+07 1.48E+07 - - - 4.2589 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19038.19038.2 0.00176 18-Oct K.LEPAFLSGLR.C "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1101.6182 1.68 51339 19038 2 1101.619814 551.8164 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3628.3 - 1.37E+06 - - - 1.4243 - 2.024 0.442 - 280.4 1 2 0 0.0016 10 0 0 0 3.13E+07 1.86E+07 - - - 4.2732 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.19039.19039.2 0.0103 14-Jul K.LLQQLFLK[136.11].A sp|Q9P287|BCCIP_HUMAN 1 1009.6416 1.35 51340 19039 2 1009.642603 505.8281 BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1 8.75 3628.4 - 1.06E+06 - - - 1.04 - 1.436 0.333 - 111.5 1 2 0 0.001 8 0 0 0 2.27E+07 1.68E+07 - - - 2.5916 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19041.19041.2 0.00773 18-Aug R.DFLLKPELLR.A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1242.7336 1.59 51342 19041 2 1242.733672 622.3741 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3628.5 - 816525 - - - 0.0507 - 1.84 0.337 - 282.8 1 2 0 0.0001 10 0 0 0 8.50E+06 5.33E+06 - - - 3.2321 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.19043.19043.2 0.00975 16-Jul K.FALNSLLQR[166.11].Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1070.6112 2.3 51344 19043 2 1070.614996 536.3129 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.75 3628.6 - 459188 - - - 3.5466 - 1.631 0.402 - 196.8 1 2 0 0.0038 9 0 0 0 4.00E+07 1.74E+07 - - - 3.4242 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.19048.19048.2 0.00144 24-Jun R.LLPPEDTQELIFK.D sp|O60287|NPA1P_HUMAN 1 1541.8341 1.39 51349 19048 2 1541.838712 771.9243 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 4.14 3629.2 - 175419 - - - 2.9841 - 1.361 0.34 - 70 1 2 0 0.0046 13 0 0 0 3.57E+06 2.57E+06 - - - 2.3419 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19052.19052.2 2.78E-05 16-Oct K.MC[160.03]LFAGFQR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1128.5209 0.87 51351 19052 2 1128.522139 565.2677 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3629.7 - 2.57E+06 - - - 1.1369 - 2.076 0.381 - 614.5 1 2 0 0.0013 9 0 0 0 8.25E+07 9.47E+07 - - - 3.9679 1 230117_WJC_METTL3_WT_vs_EV_F06.19053.19053.2 2.71E-06 18-Nov R.LMALLGQALK[136.11].W sp|Q2TAY7|SMU1_HUMAN 1 1064.6507 0.9 51352 19053 2 1064.652263 533.3326 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.75 3629.7 - 5.18E+06 - - - 1.4333 - 2.187 0.456 - 462.6 1 2 0 0.0015 10 0 0 0 3.24E+07 3.60E+07 - - - 4.5928 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.19056.19056.2 0.0212 16-Aug K.IIDGLLVMR[166.11].K "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1038.6135 3.15 51355 19056 2 1038.615355 520.314 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.84 3629.9 - 2.88E+06 - - - 1.7793 - 1.703 0.291 - 163.8 1 2 0 0.0018 9 0 0 0 9.61E+07 3.05E+07 - - - 2.73 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19057.19057.2 0.02 18-Sep R.LLLDTLQLSK.- "sp|O15357|SHIP2_HUMAN,tr|H7BXR2|H7BXR2_HUMAN" 2 1142.6911 2.56 51356 19057 2 1142.693956 572.3528 "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 OS=Homo sapiens OX=9606 GN=INPPL1 PE=1 SV=2" 5.84 3629.9 - 2.34E+06 - - - 2.5212 - 1.936 0.382 - 190.9 1 2 0 0.0029 10 0 0 0 8.04E+06 3.14E+06 - - - 3.7055 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19058.19058.2 0.0389 18-Jun R.DFLLK[136.11]PELLR[166.11].A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1260.7561 1.7 51357 19058 2 1260.757544 631.3853 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3630 - 1.12E+06 - - - 1.162 - 1.302 0.42 - 102.7 1 2 0 0.0015 10 0 0 0 9.09E+06 5.33E+06 - - - 2.8793 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.19060.19060.2 0.667 18-Sep R.LLLDTLQLSK[136.11].- "sp|O15357|SHIP2_HUMAN,tr|H7BXR2|H7BXR2_HUMAN" 2 1150.7053 2.6 51359 19060 2 1150.705733 576.3599 "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 OS=Homo sapiens OX=9606 GN=INPPL1 PE=1 SV=2" 5.84 3630.2 - 947351 - - - 0.398 - 1.447 0.263 - 149 1 2 0 0.0005 10 0 0 0 8.04E+06 3.09E+06 - - - 2.0147 0.9584 230117_WJC_METTL3_WT_vs_EV_F06.19061.19061.2 6.94 16-Apr R.VLIFSQMVR.C "sp|Q9P2D1|CHD7_HUMAN,sp|O14646|CHD1_HUMAN,sp|Q9HCK8|CHD8_HUMAN,sp|Q3L8U1|CHD9_HUMAN,sp|O14647|CHD2_HUMAN,sp|Q8TD26|CHD6_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A1B0GTU9|A0A1B0GTU9_HUMAN,tr|A0A2R8Y840|A0A2R8Y840_HUMAN,tr|H0YJG4|H0YJG4_HUMAN" 10 1091.6161 0.44 51360 19061 2 1091.616381 546.8153 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.72 3630.2 - 943521 - - - 0.2244 - 0.972 0.118 - 51 2 2 0 0.0002 9 0 0 0 9.90E+06 2.25E+07 - - - -0.3042 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.19065.19065.2 0.00036 20-Aug K.LLSAVDILGEK.F sp|Q14191|WRN_HUMAN 1 1156.6703 2.89 51364 19065 2 1156.672929 579.3424 Werner syndrome ATP-dependent helicase OS=Homo sapiens OX=9606 GN=WRN PE=1 SV=2 4.37 3630.7 - 632185 - - - 2.2383 - 1.612 0.317 - 107.2 1 2 0 0.0026 11 0 0 0 4.89E+06 1.69E+06 - - - 2.6732 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.19068.19068.2 0.112 20-Aug K.LLLNEDDYLIK[136.11].A "sp|Q52LR7|EPC2_HUMAN,tr|C9J1X4|C9J1X4_HUMAN,tr|E7ETK1|E7ETK1_HUMAN" 3 1355.7428 11.36 51367 19068 2 1355.741974 678.8787 Enhancer of polycomb homolog 2 OS=Homo sapiens OX=9606 GN=EPC2 PE=1 SV=2 4.03 3631.1 - 529412 - - - -0.5967 - 1.45 0.241 - 136.6 1 2 0 -0.0008 11 0 0 0 3.28E+07 2.89E+06 - - - 1.8259 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19069.19069.2 0.00449 14-Aug K.LDFNWVTR.W "sp|Q86W92|LIPB1_HUMAN,tr|F5GZP6|F5GZP6_HUMAN" 2 1049.5294 1.38 51368 19069 2 1049.530488 525.772 Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2 5.84 3631.1 - 457792 - - - 1.0081 - 1.682 0.451 - 192.4 1 2 0 0.0011 8 0 0 0 4.31E+06 3.13E+06 - - - 3.94 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19071.19071.2 5.97E-06 20-Oct K.GPILMELQTYR.Y "sp|P08559|ODPA_HUMAN,sp|P29803|ODPAT_HUMAN" 2 1319.6908 2.19 51370 19071 2 1319.69075 660.8527 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 6 3631.4 - 137967 - - - -0.0061 - 1.989 0.476 - 169.6 1 2 0 0 11 0 0 0 4.49E+06 2.05E+06 - - - 4.4169 1 230117_WJC_METTL3_WT_vs_EV_F06.19073.19073.2 0.000536 13/20 K.MALDIEIATYR.K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1294.6591 1.44 51371 19073 2 1294.660787 648.3368 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3631.6 - 6.61E+06 - - - 1.2853 - 2.848 0.527 - 847.6 1 2 0 0.0017 11 0 0 0 6.34E+07 4.42E+07 - - - 5.7642 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19074.19074.2 0.000125 16-Aug K.MC[160.03]LFAGFQR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1138.5291 0.87 51372 19074 2 1138.530697 570.2718 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3631.7 - 1.22E+07 - - - 1.3799 - 1.768 0.305 - 371 1 2 0 0.0016 9 0 0 0 8.25E+07 9.47E+07 - - - 2.9418 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.19075.19075.2 0.00501 14-Aug R.LSFAVPFR[166.11].E sp|P78527|PRKDC_HUMAN 1 945.5312 1.1 51373 19075 2 945.531751 473.7729 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3631.7 - 4.05E+06 - - - 0.6272 - 1.752 0.282 - 253.9 1 2 0 0.0006 8 0 0 0 2.62E+07 2.39E+07 - - - 2.8149 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.19076.19076.2 0.0116 14-Jul R.LSFAVPFR.E sp|P78527|PRKDC_HUMAN 1 935.5229 1.1 51374 19076 2 935.522743 468.7687 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3631.8 - 4.03E+06 - - - -0.155 - 1.819 0.244 - 157.7 1 2 0 -0.0001 8 0 0 0 2.63E+07 2.39E+07 - - - 2.6475 0.9883 230117_WJC_METTL3_WT_vs_EV_F06.19077.19077.2 0.721 14-May R.IPLNDLFR.C sp|P13473|LAMP2_HUMAN 1 986.5549 5.95 51375 19077 2 986.555481 494.2847 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3631.8 - 3.06E+06 - - - 0.5727 - 1.206 0.133 - 94.2 2 2 0 0.0006 8 0 0 0 7.93E+07 1.33E+07 - - - 0.4536 0.9941 230117_WJC_METTL3_WT_vs_EV_F06.19078.19078.2 0.000737 16-Jul K.VFDAIMNFK[136.11].K sp|P13639|EF2_HUMAN 1 1091.5565 4.48 51376 19078 2 1091.553365 546.7855 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.81 3631.8 - 2.78E+06 - - - -2.8748 - 1.557 0.343 - 92 1 2 0 -0.0031 9 0 0 0 9.48E+07 2.12E+07 - - - 2.8543 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.19083.19083.3 0.139 Jul-36 R.LFDQAFGLPR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1162.6135 1.22 51381 19083 3 1162.61438 388.5451 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3632.3 - 379486 - - - 0.7621 - 1.301 0.282 - 61.4 1 2 0 0.0009 10 0 0 0 2.07E+06 1.70E+06 - - - 2.4522 0.9185 230117_WJC_METTL3_WT_vs_EV_F06.19091.19091.2 2.99 14-Apr R.ILAPPGGR[166.11].S sp|Q9BPU6|DPYL5_HUMAN 1 789.4736 0.35 51387 19091 2 789.475552 395.7441 Dihydropyrimidinase-related protein 5 OS=Homo sapiens OX=9606 GN=DPYSL5 PE=1 SV=1 9.75 3633.3 - 159287 - - - 2.4181 - 0.901 0.139 - 24.8 13 2 0 0.0019 8 0 0 0 1.14E+06 3.24E+06 - - - -0.745 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.19094.19094.2 0.0611 14-Jun R.FYTIEILK.V sp|P12273|PIP_HUMAN 1 1025.5797 394.51 51389 19094 2 1025.581528 513.7971 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 6 3633.6 - 1.68E+07 - - - 1.7493 - 1.216 0.31 - 107.5 1 2 0 0.0018 8 0 0 0 3.55E+08 9.00E+05 - - - 1.9199 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.19097.19097.3 0.00476 Aug-36 R.LFDQAFGLPR[166.11].L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1172.6218 1.22 51391 19097 3 1172.622454 391.8812 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3634 - 205833 - - - 0.5884 - 1.26 0.3 - 51.5 1 2 0 0.0007 10 0 0 0 2.07E+06 1.70E+06 - - - 2.5595 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.19100.19100.2 0.00267 20-Jul R.FLMSLVNQVPK.L "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 1274.7057 1.03 51393 19100 2 1274.708193 638.3601 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 8.75 3634.3 - 1.26E+06 - - - 1.9714 - 1.531 0.353 - 128.7 1 2 0 0.0025 11 0 0 0 3.85E+07 3.75E+07 - - - 2.7997 0.999 230117_WJC_METTL3_WT_vs_EV_F06.19103.19103.2 0.0205 16-Sep K.DIVENYFMR.D "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN" 2 1185.5488 1.15 51395 19103 2 1185.550612 593.7817 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.37 3634.7 - 728770 - - - 1.4904 - 1.521 0.288 - 279.1 1 2 0 0.0018 9 0 0 0 6.58E+06 5.72E+06 - - - 2.3809 0.9905 230117_WJC_METTL3_WT_vs_EV_F06.19107.19107.2 0.114 22-Aug K.TPLPPELADVQA.- "sp|Q9Y5V0|ZN706_HUMAN,tr|H0YC70|H0YC70_HUMAN" 2 1249.6554 - 51399 19107 2 1249.657249 625.835 Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1 3.67 3635.2 - 345038 - - - 1.4652 - 1.297 0.106 - 121.4 1 2 0 0.0018 12 0 0 0 - - - - - 0.5076 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19112.19112.2 0.00424 20-Sep K.GPILMELQTYR[166.11].Y "sp|P08559|ODPA_HUMAN,sp|P29803|ODPAT_HUMAN" 2 1329.699 2 51404 19112 2 1329.7013 665.8568 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 6 3635.8 - 136579 - - - 1.7087 - 1.898 0.383 - 311.5 1 2 0 0.0023 11 0 0 0 4.10E+06 2.05E+06 - - - 3.6026 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19116.19116.2 0.102 16-Sep R.LQLPVWEYK[136.11].D sp|O43143|DHX15_HUMAN 1 1182.6528 1.67 51406 19116 2 1182.654657 592.3337 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 3636.4 - 370722 - - - 1.5313 - 1.73 0.334 - 311.8 1 2 0 0.0018 9 0 0 0 4.51E+07 2.70E+07 - - - 3.0931 0.9927 230117_WJC_METTL3_WT_vs_EV_F06.19117.19117.2 0.402 16-Aug K.SGILPILVK.C sp|O00505|IMA4_HUMAN 1 938.6165 1.2 51407 19117 2 938.62043 470.3155 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3636.4 - 273696 - - - 4.236 - 1.366 0.255 - 148.1 1 2 0 0.004 9 0 0 0 1.83E+07 1.53E+07 - - - 1.8255 0.8746 230117_WJC_METTL3_WT_vs_EV_F06.19119.19119.2 5.14 12-Jul K.FFFDPVR[166.11].K "sp|Q9NRZ9|HELLS_HUMAN,tr|A0A087WSW7|A0A087WSW7_HUMAN,tr|B1ALG6|B1ALG6_HUMAN,tr|A0A0B4J1V9|A0A0B4J1V9_HUMAN,tr|F6XU50|F6XU50_HUMAN" 5 936.4733 1.08 51409 19119 2 936.475019 469.2439 Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1 5.84 3636.6 - 302182 - - - 1.8271 - 0.913 0.01 - 97.4 1 2 0 0.0017 7 0 0 0 5.46E+06 5.07E+06 - - - -1.1741 0.8748 230117_WJC_METTL3_WT_vs_EV_F06.19120.19120.2 2.35 16-May K.DIVENYFMR[166.11].D "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN" 2 1195.5571 1.11 51410 19120 2 1195.558809 598.7858 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.37 3636.7 - 219295 - - - 1.4169 - 0.963 0.01 - 71.2 3 2 0 0.0017 9 0 0 0 6.58E+06 5.92E+06 - - - -1.2079 0.9965 230117_WJC_METTL3_WT_vs_EV_F06.19122.19122.2 0.0313 14-Aug R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 3.46 51412 19122 2 1000.557098 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3636.8 - 188880 - - - -2.2338 - 1.897 0.274 - 164.8 1 2 0 -0.0022 8 0 0 0 9.81E+06 2.84E+06 - - - 2.9951 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.19124.19124.2 4.09E-05 20-Dec K.GPILMELQTYR.Y "sp|P08559|ODPA_HUMAN,sp|P29803|ODPAT_HUMAN" 2 1319.6908 2.19 51414 19124 2 1319.698136 660.8527 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 6 3637.1 - 62558.1 - - - 5.5907 - 1.912 0.512 - 205.5 1 2 0 0.0074 11 0 0 0 4.49E+06 2.05E+06 - - - 4.5737 0.999 230117_WJC_METTL3_WT_vs_EV_F06.19131.19131.2 0.00802 18-Jun R.LEPVIMELER[166.11].Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1237.6616 0.76 51420 19131 2 1237.664884 619.8381 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3638 - 3.23E+06 - - - 2.6696 - 1.364 0.396 - 112.6 1 2 0 0.0033 10 0 0 0 5.81E+07 7.70E+07 - - - 2.8313 0.9698 230117_WJC_METTL3_WT_vs_EV_F06.19133.19133.2 0.151 16-Sep S.GDLLSEVER.N "sp|O14513|NCKP5_HUMAN,tr|A0A0A0MSE4|A0A0A0MSE4_HUMAN,tr|A0A0A0MS79|A0A0A0MS79_HUMAN" 3 1016.5138 5.63 51421 19133 2 1016.514778 509.2642 Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=2 4.14 3638.2 - 1.92E+06 - - - 0.9237 - 1.946 0.365 - 341.2 1 1 0 0.0009 9 0 0 0 5.43E+07 9.64E+06 - - - 3.6627 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.19134.19134.2 0.489 16-Jul K.SGILPILVK[136.11].C sp|O00505|IMA4_HUMAN 1 946.6307 1.2 51422 19134 2 946.631551 474.3226 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3638.3 - 1.18E+06 - - - 0.9476 - 1.219 0.3 - 105.1 1 2 0 0.0009 9 0 0 0 1.83E+07 1.53E+07 - - - 1.8294 0.9014 230117_WJC_METTL3_WT_vs_EV_F06.19135.19135.2 0.047 14-Jun R.IPLNDLFR[166.11].C sp|P13473|LAMP2_HUMAN 1 996.5632 8.37 51423 19135 2 996.572858 499.2889 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3638.4 - 645081 - - - 9.7054 - 1.345 0.248 - 101.5 1 2 0 0.0097 8 0 0 0 7.71E+07 9.21E+06 - - - 1.7636 0.998 230117_WJC_METTL3_WT_vs_EV_F06.19137.19137.2 0.616 14-Jul R.VLLLPLER[166.11].D sp|O95071|UBR5_HUMAN 1 961.62 1.57 51425 19137 2 961.622904 481.8173 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3638.6 - 480182 - - - 3.048 - 1.639 0.244 - 171.2 1 2 0 0.0029 8 0 0 0 1.18E+07 7.55E+06 - - - 2.3324 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19149.19149.2 0.00482 18-Sep R.LEPVIMELER.Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1227.6533 0.54 51436 19149 2 1227.655068 614.8339 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3640.1 - 1.12E+06 - - - 1.432 - 1.774 0.391 - 339.7 1 2 0 0.0018 10 0 0 0 3.91E+07 7.23E+07 - - - 3.5285 0.995 230117_WJC_METTL3_WT_vs_EV_F06.19150.19150.2 1.15 14-Jul R.VLLLPLER.D sp|O95071|UBR5_HUMAN 1 951.6117 1.63 51437 19150 2 951.61456 476.8131 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3640.2 - 1.62E+06 - - - 3.0023 - 1.586 0.138 - 196.1 1 2 0 0.0029 8 0 0 0 1.18E+07 7.29E+06 - - - 1.4504 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.19151.19151.2 0.000513 18-Nov K.SVVTSIFGVK.N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1035.5964 2.08 51438 19151 2 1035.601946 518.8055 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3640.3 - 594063 - - - 5.31 - 1.942 0.413 - 331.4 1 2 0 0.0055 10 0 0 0 2.17E+07 1.04E+07 - - - 3.9423 0.9938 230117_WJC_METTL3_WT_vs_EV_F06.19153.19153.2 0.00191 12-Aug R.IQLLVFK[136.11].H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 867.5673 0.73 51440 19153 2 867.569701 434.7909 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3640.5 - 531979 - - - 2.7387 - 1.704 0.057 - 184.8 1 2 0 0.0024 7 0 0 0 1.50E+07 2.06E+07 - - - 1.15 0.9959 230117_WJC_METTL3_WT_vs_EV_F06.19154.19154.2 0.107 14-Aug K.MIDLIIPR.G sp|P54886|P5CS_HUMAN 1 969.5681 1.67 51441 19154 2 969.571436 485.7913 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 5.59 3640.6 - 466351 - - - 3.417 - 1.718 0.178 - 261.4 2 2 0 0.0033 8 0 0 0 4.11E+06 2.47E+06 - - - 1.8523 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.19155.19155.2 0.00342 18-Sep K.SVVTSIFGVK[136.11].N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1043.6106 2.11 51442 19155 2 1043.613891 522.8126 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3640.7 - 394691 - - - 3.1084 - 1.957 0.363 - 205.9 1 2 0 0.0032 10 0 0 0 2.12E+07 1.00E+07 - - - 3.5952 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19156.19156.2 0.000236 24-Nov R.ALGLGLVSPAQLR.V "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|A8MRA7|A8MRA7_HUMAN" 3 1293.7769 3.04 51443 19156 2 1293.77908 647.8957 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 9.79 3640.9 - 302879 - - - 1.7074 - 2.556 0.227 - 453.9 1 2 0 0.0022 13 0 0 0 3.87E+06 1.27E+06 - - - 3.1255 0.9952 230117_WJC_METTL3_WT_vs_EV_F06.19157.19157.2 0.151 12-Jul R.IQLLVFK.H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 859.5531 0.73 51444 19157 2 859.555057 430.7838 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3641 - 272634 - - - 2.2477 - 1.591 0.087 - 148 1 2 0 0.0019 7 0 0 0 1.50E+07 2.06E+07 - - - 1.1543 0.9944 230117_WJC_METTL3_WT_vs_EV_F06.19158.19158.2 0.0406 12-Jul R.GLLEYFK[136.11].A "sp|Q6DD88|ATLA3_HUMAN,tr|F5H6I7|F5H6I7_HUMAN" 2 876.4837 1.98 51445 19158 2 876.487551 439.2491 Atlastin-3 OS=Homo sapiens OX=9606 GN=ATL3 PE=1 SV=1 6 3641.1 - 253747 - - - 4.445 - 1.332 0.307 - 119.9 1 2 0 0.0039 7 0 0 0 2.77E+06 1.40E+06 - - - 2.2156 0.9923 230117_WJC_METTL3_WT_vs_EV_F06.19159.19159.2 0.565 12-Jul R.IIIWNLR.S sp|Q14149|MORC3_HUMAN 1 926.5702 0.31 51446 19159 2 926.571983 464.2924 MORC family CW-type zinc finger protein 3 OS=Homo sapiens OX=9606 GN=MORC3 PE=1 SV=3 9.75 3641.3 - 211843 - - - 1.9545 - 1.317 0.109 - 141.9 1 2 0 0.0018 7 0 0 0 2.30E+06 7.35E+06 - - - 0.718 0.9939 230117_WJC_METTL3_WT_vs_EV_F06.19168.19168.2 0.00223 16-Aug K.LLIYWASTR.E sp|P06312|KV401_HUMAN 1 1121.6233 999 51454 19168 2 1121.629769 561.8189 Immunoglobulin kappa variable 4-1 OS=Homo sapiens OX=9606 GN=IGKV4-1 PE=1 SV=1 8.75 3642.4 - 1.58E+06 - - - 5.7408 - 1.842 0.316 - 247.1 1 2 0 0.0064 9 0 0 0 1.59E+07 0.00E+00 - - - 3.1402 0.9902 230117_WJC_METTL3_WT_vs_EV_F06.19170.19170.2 0.123 14-Sep K.GLLQLQWK[136.11].Q sp|O94826|TOM70_HUMAN 1 992.5899 1.12 51456 19170 2 992.595117 497.3022 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.75 3642.6 - 995911 - - - 5.3043 - 1.652 0.229 - 221 1 2 0 0.0053 8 0 0 0 4.97E+06 4.45E+06 - - - 2.2447 0.9876 230117_WJC_METTL3_WT_vs_EV_F06.19173.19173.2 0.0529 14-Aug K.MIDLIIPR[166.11].G sp|P54886|P5CS_HUMAN 1 979.5764 1.79 51459 19173 2 979.582409 490.7955 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 5.59 3643 - 625773 - - - 6.1414 - 1.691 0.285 - 205.6 2 2 0 0.006 8 0 0 0 3.96E+06 2.22E+06 - - - 2.594 0.9886 230117_WJC_METTL3_WT_vs_EV_F06.19175.19175.2 0.000303 20-Oct K.LIDFGSGALLK.D "sp|P11309|PIM1_HUMAN,sp|Q86V86|PIM3_HUMAN" 2 1132.6492 -1 51461 19175 2 1132.657681 567.3319 Serine\threonine-protein kinase pim-1 OS=Homo sapiens OX=9606 GN=PIM1 PE=1 SV=4 5.84 3643.3 - 349840 - - - 7.478 - 1.853 0.426 - 159.4 1 2 0 0.0085 11 0 0 0 0.00E+00 0.00E+00 - - - 3.8534 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.19176.19176.2 1.23E-06 20-Oct R.FSTIEEFSYIR[166.11].R "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1400.6852 1.42 51462 19176 2 1400.690039 701.3499 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 4.53 3643.4 - 286502 - - - 3.489 - 1.975 0.402 - 284.8 1 2 0 0.0049 11 0 0 0 1.77E+06 1.25E+06 - - - 3.8497 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.19179.19179.2 0.00079 14/22 K.LSTIALALGVER[166.11].T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1251.7426 2.01 51465 19179 2 1251.74821 626.8786 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3643.8 - 175208 - - - 4.4762 - 2.596 0.39 - 732.6 1 2 0 0.0056 12 0 0 0 2.48E+07 1.23E+07 - - - 4.4298 0.9913 230117_WJC_METTL3_WT_vs_EV_F06.19180.19180.2 0.839 20-Jul K.LFGALTPLEPR[166.11].L "sp|O14617|AP3D1_HUMAN,tr|A0A087WYN6|A0A087WYN6_HUMAN,tr|A0A2R8Y4J3|A0A2R8Y4J3_HUMAN" 3 1222.6949 1.11 51466 19180 2 1222.700364 612.3547 AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1 6 3643.9 - 133543 - - - 4.4451 - 1.57 0.208 - 108.6 1 2 0 0.0054 11 0 0 0 7.17E+05 6.44E+05 - - - 1.7958 0.997 230117_WJC_METTL3_WT_vs_EV_F06.19187.19187.2 0.0404 22-Sep R.ALEPLEGLETMR[166.11].Q "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1367.6994 -1 51472 19187 2 1367.704883 684.857 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 4.25 3644.9 - 63340 - - - 3.9928 - 1.67 0.291 - 321.8 1 2 0 0.0055 12 0 0 0 0.00E+00 0.00E+00 - - - 2.5379 1 230117_WJC_METTL3_WT_vs_EV_F06.19190.19190.2 0.00145 13/22 K.LSTIALALGVER.T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1241.7343 2.01 51475 19190 2 1241.738256 621.8744 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3645.2 - 635091 - - - 3.1561 - 2.534 0.455 - 623.1 1 2 0 0.0039 12 0 0 0 2.48E+07 1.23E+07 - - - 4.8469 1 230117_WJC_METTL3_WT_vs_EV_F06.19193.19193.2 7.58E-08 20-Nov R.FSTIEEFSYIR.R "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1390.6769 1.42 51478 19193 2 1390.685489 696.3457 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 4.53 3645.6 - 235851 - - - 6.1891 - 2.46 0.584 - 467.1 1 2 0 0.0086 11 0 0 0 1.77E+06 1.25E+06 - - - 5.7869 0.9968 230117_WJC_METTL3_WT_vs_EV_F06.19194.19194.2 0.000378 20-Oct K.ELFPIQMEGVK.L "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 1289.669 1.05 51479 19194 2 1289.676475 645.8418 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.53 3645.7 - 212964 - - - 5.8271 - 1.966 0.488 - 316.6 1 2 0 0.0075 11 0 0 0 4.13E+06 3.93E+06 - - - 4.4718 1 230117_WJC_METTL3_WT_vs_EV_F06.19199.19199.2 3.95E-07 24-Oct R.LLPGEEC[160.03]VLDGLR.V sp|O95248|MTMR5_HUMAN 1 1469.7548 1.16 51484 19199 2 1469.756502 735.8847 Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4 4.14 3646.3 - 88407.8 - - - 1.1478 - 2.187 0.521 - 307 1 2 0 0.0017 13 0 0 0 1.60E+06 1.37E+06 - - - 4.897 0.995 230117_WJC_METTL3_WT_vs_EV_F06.19205.19205.2 0.025 18-Oct R.IIVAIDGWPR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1138.6499 2.36 51489 19205 2 1138.652983 570.3322 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3646.9 - 9.94E+06 - - - 2.726 - 2.131 0.022 - 315.9 1 2 0 0.0031 10 0 0 0 5.52E+07 2.34E+07 - - - 1.3144 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.19207.19207.2 0.00226 18-Sep R.IIVAIDGWPR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1148.6581 2.44 51491 19207 2 1148.663096 575.3364 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3647 - 5.41E+06 - - - 4.3068 - 2.031 0.353 - 257.6 1 2 0 0.0049 10 0 0 0 5.72E+07 2.34E+07 - - - 3.6244 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.19210.19210.2 4.79E-05 18-Oct K.LYSVVSQLIR.C "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 1176.6867 1.33 51494 19210 2 1176.690427 589.3506 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3647.2 - 3.47E+06 - - - 3.2022 - 1.914 0.379 - 337.3 1 2 0 0.0038 10 0 0 0 6.41E+06 4.83E+06 - - - 3.6512 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19211.19211.2 0.00527 14-Aug K.ILTPIIFK.E "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5L9|H7C5L9_HUMAN" 4 943.6106 0.76 51495 19211 2 943.612903 472.8126 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 8.75 3647.2 - 2.61E+06 - - - 2.3982 - 1.794 0.462 - 188.8 1 2 0 0.0023 8 0 0 0 9.52E+06 1.26E+07 - - - 4.2153 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19212.19212.2 1.18E-06 20-Dec R.TSLALDESLFR[166.11].G "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|H0YJH9|H0YJH9_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 5 1260.6589 1.42 51496 19212 2 1260.662708 631.3367 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.37 3647.3 - 2.13E+06 - - - 2.9913 - 2.803 0.362 - 836 1 2 0 0.0038 11 0 0 0 1.91E+07 1.34E+07 - - - 4.5018 1 230117_WJC_METTL3_WT_vs_EV_F06.19213.19213.2 1.37E-05 16-Oct R.QINWTVLYR.R "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1191.64 1.06 51497 19213 2 1191.643131 596.8273 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 8.75 3647.4 - 1.78E+06 - - - 2.5914 - 2.134 0.483 - 662.6 1 2 0 0.0031 9 0 0 0 2.82E+07 2.67E+07 - - - 4.8004 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.19216.19216.2 0.297 14-Oct K.LAIVLFTK.E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 903.5793 2.02 51500 19216 2 903.580844 452.7969 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3647.6 - 1.18E+06 - - - 1.6645 - 1.972 0.201 - 262.3 1 2 0 0.0015 8 0 0 0 3.68E+06 1.83E+06 - - - 2.5731 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.19220.19220.2 0.000782 24-Aug K.FIAELGVPLSQVK.S sp|Q86T24|KAISO_HUMAN 1 1399.8075 4 51504 19220 2 1399.814166 700.911 Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2 6 3648.1 - 783357 - - - 4.7607 - 1.877 0.373 - 171.6 1 2 0 0.0067 13 0 0 0 1.80E+06 4.49E+05 - - - 3.41 0.9497 230117_WJC_METTL3_WT_vs_EV_F06.19221.19221.2 0.000964 24-Sep R.SYEAVAAAAASVY.N sp|Q9BWF3|RBM4_HUMAN 1 1271.6034 - 51505 19221 2 1271.606901 636.809 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4 3648.2 - 782040 - - - 2.7666 - 1.666 0.426 - 238.3 1 1 0 0.0035 13 0 0 0 - - - - - 3.4964 0.993 230117_WJC_METTL3_WT_vs_EV_F06.19225.19225.2 0.281 14-Jul K.LAIVLFTK[136.11].E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 911.5935 2.02 51508 19225 2 911.595258 456.804 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3648.8 - 387390 - - - 1.8846 - 1.519 0.065 - 106.2 1 2 0 0.0017 8 0 0 0 3.68E+06 1.83E+06 - - - 0.7814 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19226.19226.2 0.00573 16-Sep K.VFSIGPVFR.A sp|P14868|SYDC_HUMAN 1 1020.5757 1.12 51509 19226 2 1020.577601 511.2951 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3648.9 - 4.38E+06 - - - 1.9097 - 1.778 0.399 - 323.2 1 2 0 0.0019 9 0 0 0 2.97E+07 2.65E+07 - - - 3.6523 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19227.19227.2 0.00415 16-Aug K.VFSIGPVFR[166.11].A sp|P14868|SYDC_HUMAN 1 1030.5839 1.12 51510 19227 2 1030.585076 516.2992 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3648.9 - 4.29E+06 - - - 1.1198 - 1.796 0.351 - 233.1 1 2 0 0.0012 9 0 0 0 2.97E+07 2.65E+07 - - - 3.3272 1 230117_WJC_METTL3_WT_vs_EV_F06.19229.19229.2 1.69E-06 18-Nov R.LWIANYSLPR.A sp|O43172|PRP4_HUMAN 1 1231.6713 3.14 51512 19229 2 1231.674046 616.8429 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3649.1 - 1.20E+06 - - - 2.1946 - 2.32 0.549 - 625.5 1 2 0 0.0027 10 0 0 0 5.86E+07 1.87E+07 - - - 5.4441 1 230117_WJC_METTL3_WT_vs_EV_F06.19231.19231.2 1.24E-06 16-Oct K.MDLVTYFGK.R sp|P09543|CN37_HUMAN 1 1072.5263 4.75 51514 19231 2 1072.527104 537.2704 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 5.59 3649.2 - 911178 - - - 0.7328 - 2.159 0.504 - 404.3 1 2 0 0.0008 9 0 0 0 8.23E+06 1.73E+06 - - - 4.9899 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19236.19236.2 0.000126 12-Aug K.FGFIGFK[136.11].S sp|Q9Y4C8|RBM19_HUMAN 1 822.452 0.87 51519 19236 2 822.452455 412.2333 Probable RNA-binding protein 19 OS=Homo sapiens OX=9606 GN=RBM19 PE=1 SV=3 8.75 3649.8 - 276693 - - - 0.6006 - 1.627 0.464 - 163.8 1 2 0 0.0005 7 0 0 0 2.35E+06 2.70E+06 - - - 4.0102 0.986 230117_WJC_METTL3_WT_vs_EV_F06.19249.19249.2 0.0749 12-Jun K.QFLDYFK[136.11].T "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 967.4895 1.43 51530 19249 2 967.493895 484.752 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.83 3651.5 - 896424 - - - 4.5747 - 1.207 0.247 - 121.6 1 2 0 0.0044 7 0 0 0 6.95E+06 4.87E+06 - - - 1.4601 1 230117_WJC_METTL3_WT_vs_EV_F06.19250.19250.2 0.0054 20-Dec R.GVIFTEAFVAR.H sp|O94874|UFL1_HUMAN 1 1208.6554 1.54 51531 19250 2 1208.661167 605.335 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 6 3651.6 - 894550 - - - 4.8053 - 2.594 0.429 - 404.7 1 2 0 0.0058 11 0 0 0 6.39E+06 4.15E+06 - - - 4.7864 0.9965 230117_WJC_METTL3_WT_vs_EV_F06.19253.19253.2 0.00248 18-Aug K.LLVLSALAEK.L sp|Q13395|TARB1_HUMAN 1 1055.659 1.6 51534 19253 2 1055.664798 528.8368 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6 3652 - 659766 - - - 5.4478 - 1.717 0.426 - 106.9 1 2 0 0.0058 10 0 0 0 3.43E+06 2.14E+06 - - - 3.6945 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.19254.19254.2 1.65E-05 18-Sep K.ELPEYYELIR.K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1323.6711 1.62 51535 19254 2 1323.677207 662.8428 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3652.1 - 538298 - - - 4.6379 - 2.097 0.379 - 342.5 1 2 0 0.0061 10 0 0 0 8.97E+06 5.55E+06 - - - 3.9053 0.9904 230117_WJC_METTL3_WT_vs_EV_F06.19255.19255.2 0.217 18-Sep R.IIGYGLPFPK.N sp|Q9UDY4|DNJB4_HUMAN 1 1103.6379 9.64 51536 19255 2 1103.644194 552.8262 DnaJ homolog subfamily B member 4 OS=Homo sapiens OX=9606 GN=DNAJB4 PE=1 SV=1 8.59 3652.2 - 533724 - - - 5.6866 - 1.86 0.239 - 125.9 1 2 0 0.0063 10 0 0 0 3.31E+06 3.43E+05 - - - 2.5365 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.19256.19256.2 0.000154 18-Oct K.ELPEYYELIR[166.11].K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1333.6793 1.62 51537 19256 2 1333.685725 667.8469 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3652.4 - 461924 - - - 4.789 - 1.849 0.394 - 402.7 1 2 0 0.0064 10 0 0 0 8.97E+06 5.55E+06 - - - 3.6647 0.9791 230117_WJC_METTL3_WT_vs_EV_F06.19266.19266.2 0.0299 14-Jun K.DDIPVFLR.H "sp|Q9UBB4|ATX10_HUMAN,tr|B1AHE4|B1AHE4_HUMAN,tr|A0A1W2PQD2|A0A1W2PQD2_HUMAN" 3 973.5233 1.3 51546 19266 2 973.528686 487.7689 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 4.21 3653.6 - 347061 - - - 5.551 - 1.201 0.283 - 95.1 1 2 0 0.0054 8 0 0 0 1.11E+07 8.56E+06 - - - 1.6819 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19268.19268.2 0.000215 18-Sep R.LWIANYSLPR[166.11].A sp|O43172|PRP4_HUMAN 1 1241.6796 3.14 51547 19268 2 1241.681794 621.8471 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3653.9 - 5.06E+06 - - - 1.7565 - 2.164 0.43 - 257.3 1 2 0 0.0022 10 0 0 0 5.87E+07 1.87E+07 - - - 4.3711 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19270.19270.2 0.000121 18-Aug R.SIPMTVDFIR.L sp|P00492|HPRT_HUMAN 1 1177.6165 2.16 51549 19270 2 1177.619985 589.8155 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 5.55 3654 - 1.76E+06 - - - 2.9339 - 1.808 0.507 - 267.1 1 2 0 0.0035 10 0 0 0 1.18E+07 5.47E+06 - - - 4.4377 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.19271.19271.2 5.27E-05 18-Oct R.FFLSSGLIDK[136.11].V sp|Q9BTV4|TMM43_HUMAN 1 1133.6212 0.89 51550 19271 2 1133.626555 567.8179 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 5.84 3654.1 - 1.47E+06 - - - 4.7141 - 1.917 0.442 - 235.1 1 2 0 0.0053 10 0 0 0 6.72E+06 7.52E+06 - - - 4.1204 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19272.19272.2 0.000337 16-Aug K.IFAFDLDAK[136.11].R sp|Q96P11|NSUN5_HUMAN 1 1046.5528 0.79 51551 19272 2 1046.554893 524.2837 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 4.21 3654.2 - 1.40E+06 - - - 2.0028 - 1.685 0.421 - 125.6 1 2 0 0.0021 9 0 0 0 6.61E+06 8.34E+06 - - - 3.6593 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.19273.19273.2 0.00161 16-Sep K.ISVNDFIIK[136.11].A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1055.6106 0.83 51552 19273 2 1055.615095 528.8126 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 3654.3 - 1.34E+06 - - - 4.2137 - 2.094 0.313 - 150.7 1 2 0 0.0044 9 0 0 0 6.27E+06 7.59E+06 - - - 3.4896 1 230117_WJC_METTL3_WT_vs_EV_F06.19274.19274.2 0.000743 16-Oct K.IFAFDLDAK.R sp|Q96P11|NSUN5_HUMAN 1 1038.5386 0.83 51553 19274 2 1038.540362 520.2766 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 4.21 3654.4 - 1.28E+06 - - - 1.6995 - 1.943 0.51 - 265.9 1 2 0 0.0018 9 0 0 0 6.61E+06 7.96E+06 - - - 4.729 1 230117_WJC_METTL3_WT_vs_EV_F06.19275.19275.2 3.20E-06 22-Dec R.VVYSAFLMATPR.L sp|Q15029|U5S1_HUMAN 1 1353.7115 1.52 51554 19275 2 1353.715519 677.863 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.72 3654.5 - 1.13E+06 - - - 2.974 - 2.411 0.479 - 455.1 1 2 0 0.004 12 0 0 0 6.86E+06 4.52E+06 - - - 4.8932 1 230117_WJC_METTL3_WT_vs_EV_F06.19276.19276.2 2.83E-07 22-Oct R.VVYSAFLMATPR[166.11].L sp|Q15029|U5S1_HUMAN 1 1363.7198 1.52 51555 19276 2 1363.724657 682.8672 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.72 3654.7 - 757680 - - - 3.5887 - 2.37 0.61 - 335 1 2 0 0.0049 12 0 0 0 6.86E+06 4.52E+06 - - - 5.8153 0.9918 230117_WJC_METTL3_WT_vs_EV_F06.19277.19277.2 0.697 14-Aug K.LFVGFLNR.A "sp|Q9NXE4|NSMA3_HUMAN,tr|H7C0W5|H7C0W5_HUMAN,tr|H7C2E2|H7C2E2_HUMAN,tr|H7C2J2|H7C2J2_HUMAN,tr|H7C1Q6|H7C1Q6_HUMAN,tr|H7C235|H7C235_HUMAN,tr|A0A7P0TB44|A0A7P0TB44_HUMAN,tr|A0A7P0T9J6|A0A7P0T9J6_HUMAN,tr|A0A7P0TB24|A0A7P0TB24_HUMAN" 9 964.5494 2.13 51556 19277 2 964.554252 483.282 Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3 9.75 3654.8 - 645415 - - - 4.992 - 1.636 0.229 - 227.1 1 2 0 0.0048 8 0 0 0 9.13E+06 4.29E+06 - - - 2.2155 0.9845 230117_WJC_METTL3_WT_vs_EV_F06.19278.19278.2 2.57 12-Jun R.LWAELLR[166.11].T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN" 3 909.5312 1.51 51557 19278 2 909.534429 455.7729 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 6 3654.9 - 634016 - - - 3.5964 - 1.357 0.115 - 113.5 1 2 0 0.0033 7 0 0 0 3.58E+06 2.38E+06 - - - 0.8566 0.999 230117_WJC_METTL3_WT_vs_EV_F06.19279.19279.2 0.000844 18-Aug R.FMEPYIFGSR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 1255.5935 0.92 51558 19279 2 1255.597688 628.804 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 6 3655.1 - 561587 - - - 3.3355 - 1.779 0.38 - 232.5 1 2 0 0.0042 10 0 0 0 2.59E+06 2.80E+06 - - - 3.4543 1 230117_WJC_METTL3_WT_vs_EV_F06.19280.19280.2 0.00195 13/22 R.LC[160.03]LTDEEVVFVR.L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1478.7439 8.57 51559 19280 2 1478.749222 740.3792 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3655.2 - 538226 - - - 3.5882 - 2.636 0.516 - 669 1 2 0 0.0053 12 0 0 0 2.71E+06 3.17E+05 - - - 5.4008 0.993 230117_WJC_METTL3_WT_vs_EV_F06.19281.19281.2 0.0655 12-Jul R.LWAELLR.T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN" 3 899.5229 1.51 51560 19281 2 899.521858 450.7687 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 6 3655.3 - 524011 - - - -1.1451 - 1.537 0.158 - 183 1 2 0 -0.001 7 0 0 0 3.58E+06 2.38E+06 - - - 1.5696 1 230117_WJC_METTL3_WT_vs_EV_F06.19282.19282.2 0.00012 14/22 K.VLGTEELYGYLK.K "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1383.7286 1.03 51561 19282 2 1383.733309 692.8716 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.53 3655.5 - 473778 - - - 3.4154 - 2.648 0.524 - 549.3 1 2 0 0.0047 12 0 0 0 7.32E+06 7.08E+06 - - - 5.472 1 230117_WJC_METTL3_WT_vs_EV_F06.19284.19284.2 0.000131 13/22 K.VLGTEELYGYLK[136.11].K "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1391.7428 1.03 51563 19284 2 1391.747503 696.8787 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.53 3655.7 - 388557 - - - 3.3914 - 2.411 0.481 - 452.2 1 2 0 0.0047 12 0 0 0 7.32E+06 7.08E+06 - - - 4.9077 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.19285.19285.2 0.0105 14-Jun K.GLLDVLPK[136.11].N "sp|O95071|UBR5_HUMAN,tr|E7ET84|E7ET84_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 861.5415 2.42 51564 19285 2 861.542275 431.778 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.84 3655.8 - 296024 - - - 0.8949 - 1.133 0.385 - 71.9 1 2 0 0.0008 8 0 0 0 8.94E+06 3.70E+06 - - - 2.261 1 230117_WJC_METTL3_WT_vs_EV_F06.19286.19286.2 7.92E-07 13/24 V.ALVMLQEDELLSK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1495.8047 1.53 51565 19286 2 1495.812693 748.9096 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3656 - 226992 - - - 5.3222 - 2.834 0.391 - 551 1 1 0 0.008 13 0 0 0 1.83E+07 1.19E+07 - - - 4.6 1 230117_WJC_METTL3_WT_vs_EV_F06.19292.19292.2 2.04E-07 16/24 V.ALVMLQEDELLSK.M sp|Q96A49|SYAP1_HUMAN 1 1487.7905 1.53 51569 19292 2 1487.7958 744.9025 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3656.7 - 2.99E+06 - - - 3.5408 - 3.033 0.515 - 873.5 1 1 0 0.0053 13 0 0 0 1.83E+07 1.19E+07 - - - 5.6908 0.9018 230117_WJC_METTL3_WT_vs_EV_F06.19293.19293.2 0.00184 18-Oct R.VTIMGIYSIK[136.11].K "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 3 1131.6453 2.03 51570 19293 2 1131.653992 566.8299 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 8.56 3656.8 - 1.77E+06 - - - 7.6649 - 1.872 0.1 - 267.1 2 2 0 0.0087 10 0 0 0 1.31E+07 6.47E+06 - - - 1.3926 0.9692 230117_WJC_METTL3_WT_vs_EV_F06.19294.19294.2 0.18 16-Aug K.ISVNDFIIK.A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1047.5964 0.83 51571 19294 2 1047.602542 524.8055 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 3656.9 - 1.71E+06 - - - 5.8181 - 1.429 0.193 - 98.7 1 2 0 0.0061 9 0 0 0 6.27E+06 7.59E+06 - - - 1.4973 0.9659 230117_WJC_METTL3_WT_vs_EV_F06.19295.19295.2 0.265 14-Jun R.ILPWSTFR[166.11].L "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1028.5683 0.52 51572 19295 2 1028.573381 515.2914 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3657 - 998988 - - - 4.9671 - 1.099 0.221 - 119.5 1 2 0 0.0051 8 0 0 0 5.69E+06 1.09E+07 - - - 0.9564 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.19297.19297.2 6.75E-06 14/24 R.IPSPLGYAAIPIK[136.11].F sp|Q9Y3A4|RRP7A_HUMAN 1 1346.8053 1.52 51574 19297 2 1346.811203 674.4099 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 8.59 3657.3 - 597890 - - - 4.3651 - 2.138 0.475 - 326.2 1 2 0 0.0059 13 0 0 0 3.89E+07 2.56E+07 - - - 4.4977 1 230117_WJC_METTL3_WT_vs_EV_F06.19299.19299.2 6.34E-08 20-Nov R.FFDEESYSLLR.K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1404.6561 1.63 51576 19299 2 1404.660093 703.3353 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3657.5 - 452469 - - - 2.8099 - 2.411 0.581 - 256.2 1 2 0 0.0039 11 0 0 0 4.89E+07 3.01E+07 - - - 5.7117 1 230117_WJC_METTL3_WT_vs_EV_F06.19300.19300.2 5.64E-05 16/26 R.WSSLAC[160.03]NIALDAVK.M "sp|P49368|TCPG_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1546.7814 -1 51577 19300 2 1546.788577 774.398 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.83 3657.6 - 429861 - - - 4.6632 - 2.856 0.576 - 850.4 1 2 0 0.0072 14 0 0 0 0.00E+00 0.00E+00 - - - 5.9265 1 230117_WJC_METTL3_WT_vs_EV_F06.19301.19301.2 1.78E-10 13/20 R.FFDEESYSLLR[166.11].K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1414.6644 1.63 51578 19301 2 1414.669272 708.3395 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3657.8 - 390828 - - - 3.4326 - 2.568 0.504 - 405.2 1 2 0 0.0049 11 0 0 0 4.89E+07 3.01E+07 - - - 5.3134 1 230117_WJC_METTL3_WT_vs_EV_F06.19304.19304.2 6.99E-07 15/22 R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.3 51581 19304 2 1315.792258 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3658.2 - 303009 - - - 4.4726 - 2.572 0.608 - 614.5 1 2 0 0.0059 12 0 0 0 1.50E+09 1.15E+09 - - - 6.0155 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.19306.19306.2 6.28E-05 20-Sep K.ELLDTELDLYK[136.11].K "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1358.7061 -1 51583 19306 2 1358.713303 680.3603 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 3.92 3658.4 - 266094 - - - 5.3286 - 1.967 0.412 - 261.4 1 2 0 0.0072 11 0 0 0 0.00E+00 0.00E+00 - - - 3.9119 1 230117_WJC_METTL3_WT_vs_EV_F06.19312.19312.2 0.000366 22-Nov R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.3 51587 19312 2 1323.802705 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3659.2 - 6.63E+07 - - - 1.6105 - 2.107 0.494 - 299.3 1 2 0 0.0021 12 0 0 0 1.50E+09 1.15E+09 - - - 4.6499 1 230117_WJC_METTL3_WT_vs_EV_F06.19314.19314.2 6.96E-05 13/26 K.VLELDPALAPVVSR.E "sp|O00170|AIP_HUMAN,tr|A0A804HKK3|A0A804HKK3_HUMAN,tr|A0A804HKL7|A0A804HKL7_HUMAN,tr|A0A804HJ46|A0A804HJ46_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN" 6 1477.8504 7.48 51589 19314 2 1477.851205 739.9325 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 4.37 3659.4 - 3.60E+06 - - - 0.5244 - 2.761 0.538 - 418.8 1 2 0 0.0008 14 0 0 0 1.15E+07 1.54E+06 - - - 5.563 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19315.19315.2 0.000646 14-Sep R.WALGQVFR[166.11].Q "sp|P26572|MGAT1_HUMAN,tr|D6RF69|D6RF69_HUMAN" 2 985.5373 1.38 51590 19315 2 985.537708 493.7759 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 9.75 3659.4 - 3.35E+06 - - - 0.4079 - 1.877 0.418 - 421.5 1 2 0 0.0004 8 0 0 0 1.18E+07 8.59E+06 - - - 4.0273 1 230117_WJC_METTL3_WT_vs_EV_F06.19316.19316.2 1.38E-05 24-Dec R.IITLTGPTNAIFK[136.11].A sp|Q15365|PCBP1_HUMAN 1 1395.8217 3.66 51591 19316 2 1395.823173 698.9181 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3659.5 - 3.07E+06 - - - 1.0539 - 2.46 0.522 - 392 1 2 0 0.0015 13 0 0 0 1.69E+08 4.61E+07 - - - 5.2063 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19317.19317.2 0.273 16-Oct R.VLEALLPLK.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 994.6427 1.78 51592 19317 2 994.643603 498.3286 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3659.6 - 2.69E+06 - - - 0.939 - 2.057 0.352 - 329.4 1 2 0 0.0009 9 0 0 0 1.07E+08 6.03E+07 - - - 3.7272 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19318.19318.2 0.0122 22-Oct K.ATGILLYGLASR.L "sp|P47897|SYQ_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|F2Z2V6|F2Z2V6_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 9 1233.7081 1.43 51593 19318 2 1233.710408 617.8613 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 8.79 3659.6 - 2.17E+06 - - - 1.853 - 2.128 0.409 - 315.4 1 2 0 0.0023 12 0 0 0 1.36E+07 9.49E+06 - - - 4.0482 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.19320.19320.2 1.1 16-Sep R.VLEALLPLK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1002.6569 1.78 51595 19320 2 1002.657013 502.3357 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3659.8 - 1.95E+06 - - - 0.1436 - 1.829 0.303 - 267.2 1 2 0 0.0001 9 0 0 0 1.07E+08 6.04E+07 - - - 3.0256 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.19322.19322.2 0.035 18-Aug K.VPSLVGSFIR[166.11].S "sp|P78417|GSTO1_HUMAN,tr|Q5TA02|Q5TA02_HUMAN" 2 1083.6316 0.93 51597 19322 2 1083.63392 542.8231 Glutathione S-transferase omega-1 OS=Homo sapiens OX=9606 GN=GSTO1 PE=1 SV=2 9.72 3659.9 - 940196 - - - 2.1409 - 1.491 0.245 - 132.9 1 2 0 0.0023 10 0 0 0 4.35E+06 4.69E+06 - - - 1.9648 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19325.19325.2 0.00129 18-Sep R.VIEQLLVGLK.D "sp|Q9BTW9|TBCD_HUMAN,tr|A0A804HJ32|A0A804HJ32_HUMAN,tr|A0A804HKT8|A0A804HKT8_HUMAN,tr|A0A804HHW7|A0A804HHW7_HUMAN,tr|A0A804HL21|A0A804HL21_HUMAN,tr|A0A804HKB9|A0A804HKB9_HUMAN,tr|A0A804HJY5|A0A804HJY5_HUMAN,tr|A0A804HI02|A0A804HI02_HUMAN,tr|A0A804HIU1|A0A804HIU1_HUMAN,tr|A0A804HJ57|A0A804HJ57_HUMAN,tr|A0A804HLF8|A0A804HLF8_HUMAN,tr|A0A804HL62|A0A804HL62_HUMAN,tr|A0A804HIC0|A0A804HIC0_HUMAN,tr|J3KR97|J3KR97_HUMAN,tr|A0A804HI57|A0A804HI57_HUMAN,tr|A0A804HIN6|A0A804HIN6_HUMAN,tr|A0A804HLI2|A0A804HLI2_HUMAN" 17 1110.7012 1.37 51600 19325 2 1110.702142 556.3579 Tubulin-specific chaperone D OS=Homo sapiens OX=9606 GN=TBCD PE=1 SV=2 5.97 3660.3 - 904994 - - - 0.8067 - 1.995 0.407 - 177.7 1 2 0 0.0009 10 0 0 0 1.97E+06 1.43E+06 - - - 3.9746 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.19326.19326.3 0.000893 Dec-44 R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.05 51601 19326 3 1323.801131 442.2741 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3660.4 - 880110 - - - 0.4215 - 1.97 0.421 - 170.5 1 2 0 0.0006 12 0 0 0 1.12E+07 1.07E+07 - - - 5.113 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19327.19327.2 0.0692 13/24 K.LGLSLVVPGGGIK.K sp|Q99747|SNAG_HUMAN 1 1208.7493 2.74 51602 19327 2 1208.752426 605.3819 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3660.5 - 798343 - - - 2.6201 - 2.592 0.32 - 419.1 1 2 0 0.0032 13 0 0 0 5.56E+06 2.03E+06 - - - 3.848 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.19334.19334.3 1.80E-05 16/44 R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 0.72 51608 19334 3 1315.786293 439.6027 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3661.3 - 653544 - - - -0.0608 - 2.41 0.495 - 289 1 2 0 -0.0001 12 0 0 0 1.13E+07 1.57E+07 - - - 6.4969 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19337.19337.2 0.000773 16-Dec K.TLEEILLER.A "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 3 1114.6234 1.67 51611 19337 2 1114.623237 558.319 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.25 3661.7 - 679743 - - - -0.1373 - 2.197 0.404 - 396.1 1 2 0 -0.0002 9 0 0 0 5.89E+07 3.53E+07 - - - 4.302 0.9959 230117_WJC_METTL3_WT_vs_EV_F06.19338.19338.2 1.95 16-Aug R.LSYPTFFPR.F "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1126.5811 2.06 51612 19338 2 1126.582363 564.2978 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 8.75 3661.8 - 658469 - - - 1.0936 - 1.453 0.138 - 145.8 1 2 0 0.0012 9 0 0 0 2.34E+07 1.14E+07 - - - 1.1408 1 230117_WJC_METTL3_WT_vs_EV_F06.19352.19352.2 0.00121 18-Oct R.LGLDDFESLK.V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1135.5761 0.42 51625 19352 2 1135.577617 568.7953 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3663.5 - 1.61E+06 - - - 1.3315 - 2.377 0.451 - 180.7 1 2 0 0.0015 10 0 0 0 5.88E+07 1.40E+08 - - - 4.7884 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19355.19355.2 0.00131 14-Aug K.LVYVDLLR.E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 989.591 1.94 51628 19355 2 989.593835 495.8028 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.84 3663.8 - 1.06E+06 - - - 2.8982 - 1.669 0.415 - 253.6 1 2 0 0.0029 8 0 0 0 4.23E+07 2.17E+07 - - - 3.6501 1 230117_WJC_METTL3_WT_vs_EV_F06.19358.19358.2 9.84E-05 16-Nov K.LPFPIIDDR[166.11].N sp|P30041|PRDX6_HUMAN 1 1094.6 1.28 51631 19358 2 1094.599616 548.3073 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.21 3664.1 - 786999 - - - -0.3198 - 2.282 0.447 - 607.2 1 2 0 -0.0003 9 0 0 0 8.23E+07 6.45E+07 - - - 4.7294 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.19359.19359.2 0.0851 16-Sep K.LSPEELLLR.W "sp|P13797|PLST_HUMAN,sp|Q14651|PLSI_HUMAN,sp|P13796|PLSL_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|C9JAM8|C9JAM8_HUMAN" 5 1068.6179 2.6 51632 19359 2 1068.618094 535.3162 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.53 3664.3 - 612754 - - - 0.1722 - 1.771 0.212 - 181.4 1 2 0 0.0002 9 0 0 0 3.93E+07 1.51E+07 - - - 2.2603 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19360.19360.2 0.0368 12-Aug R.SGMFWLR.F sp|P31930|QCR1_HUMAN 1 895.4374 1.24 51633 19360 2 895.43775 448.726 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 9.47 3664.4 - 455688 - - - 0.3417 - 1.763 0.382 - 300.5 1 2 0 0.0003 7 0 0 0 6.51E+06 5.27E+06 - - - 3.659 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19365.19365.2 0.0325 16-Jul K.LPFPIIDDR.N sp|P30041|PRDX6_HUMAN 1 1084.5917 1.25 51636 19365 2 1084.59225 543.3031 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.21 3665.1 - 6.87E+06 - - - 0.5108 - 1.696 0.367 - 222 1 2 0 0.0006 9 0 0 0 8.32E+07 6.67E+07 - - - 3.2798 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.19367.19367.2 9.63E-05 16-Jun R.WLVFDEADR[166.11].L "sp|Q9H8H2|DDX31_HUMAN,tr|F8WAJ0|F8WAJ0_HUMAN" 2 1159.5537 1.01 51638 19367 2 1159.558399 580.7841 Probable ATP-dependent RNA helicase DDX31 OS=Homo sapiens OX=9606 GN=DDX31 PE=1 SV=2 4.03 3665.2 - 258523 - - - 4.0145 - 1.758 0.39 - 82.8 1 2 0 0.0047 9 0 0 0 1.94E+06 1.93E+06 - - - 3.5523 1 230117_WJC_METTL3_WT_vs_EV_F06.19370.19370.2 0.00143 18-Nov R.LGLDDFESLK[136.11].V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1143.5903 0.42 51640 19370 2 1143.591127 572.8024 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3665.6 - 5.25E+07 - - - 0.7188 - 2.366 0.564 - 293.9 1 2 0 0.0008 10 0 0 0 5.88E+07 1.40E+08 - - - 5.6103 1 230117_WJC_METTL3_WT_vs_EV_F06.19372.19372.2 5.60E-06 19/24 R.TPFTTAQLLALER.K sp|P28360|MSX1_HUMAN 1 1459.8035 1.58 51641 19372 2 1459.800306 730.909 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3665.8 - 4.14E+06 - - - -2.1736 - 3.214 0.604 - 1615.7 1 2 0 -0.0032 13 0 0 0 1.76E+07 1.12E+07 - - - 6.4976 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19373.19373.2 0.00104 20-Nov R.LLGLGVTDFSR[166.11].A "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 1186.6585 0.68 51642 19373 2 1186.658147 594.3365 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 5.84 3665.9 - 3.86E+06 - - - -0.3337 - 2.308 0.417 - 382.2 1 2 0 -0.0004 11 0 0 0 1.19E+07 1.76E+07 - - - 4.3834 1 230117_WJC_METTL3_WT_vs_EV_F06.19375.19375.2 3.29E-05 15/24 R.TPFTTAQLLALER[166.11].K sp|P28360|MSX1_HUMAN 1 1469.8117 1.58 51644 19375 2 1469.810405 735.9132 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3666.1 - 2.19E+06 - - - -0.9144 - 2.962 0.557 - 731 1 2 0 -0.0013 13 0 0 0 1.76E+07 1.12E+07 - - - 5.9415 0.9372 230117_WJC_METTL3_WT_vs_EV_F06.19376.19376.2 6.13 16-Jun K.LSPEELLLR[166.11].W "sp|P13797|PLST_HUMAN,sp|Q14651|PLSI_HUMAN,sp|P13796|PLSL_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|C9JAM8|C9JAM8_HUMAN" 5 1078.6262 2.56 51645 19376 2 1078.626339 540.3204 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.53 3666.2 - 1.95E+06 - - - 0.1474 - 1.3 0.007 - 53.9 8 2 0 0.0002 9 0 0 0 3.78E+07 1.47E+07 - - - -0.5517 0.999 230117_WJC_METTL3_WT_vs_EV_F06.19378.19378.2 0.0116 18-Oct K.LFLELEPQVR[166.11].D "sp|Q13098|CSN1_HUMAN,tr|A0A096LP07|A0A096LP07_HUMAN,tr|A8K070|A8K070_HUMAN,tr|C9JFE4|C9JFE4_HUMAN,tr|A0A096LPJ3|A0A096LPJ3_HUMAN" 5 1252.7055 3.12 51647 19378 2 1252.704326 627.36 COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4 4.53 3666.5 - 1.72E+06 - - - -0.9316 - 2.027 0.364 - 384 1 2 0 -0.0012 10 0 0 0 2.14E+07 6.85E+06 - - - 3.7014 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.19379.19379.2 0.0581 18-Aug R.LLLQIPSTIR[166.11].S sp|Q16394|EXT1_HUMAN 1 1162.7313 -1 51648 19379 2 1162.732146 582.3729 Exostosin-1 OS=Homo sapiens OX=9606 GN=EXT1 PE=1 SV=2 9.75 3666.6 - 1.67E+06 - - - 0.7156 - 1.836 0.22 - 183.8 1 2 0 0.0008 10 0 0 0 0.00E+00 0.00E+00 - - - 2.3616 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.19381.19381.2 0.0405 18-Jun R.LLLQIPSTIR.S sp|Q16394|EXT1_HUMAN 1 1152.723 0.79 51650 19381 2 1152.723404 577.3688 Exostosin-1 OS=Homo sapiens OX=9606 GN=EXT1 PE=1 SV=2 9.75 3666.8 - 1.33E+06 - - - 0.3123 - 1.481 0.216 - 92.9 2 2 0 0.0004 10 0 0 0 3.89E+06 4.93E+06 - - - 1.598 0.996 230117_WJC_METTL3_WT_vs_EV_F06.19384.19384.2 0.535 14-Jul K.ELEPFLLR[166.11].R sp|O14646|CHD1_HUMAN 1 1025.5785 0.57 51653 19384 2 1025.581954 513.7965 Chromodomain-helicase-DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=CHD1 PE=1 SV=2 4.53 3667.2 - 811954 - - - 3.3659 - 1.549 0.201 - 216.5 1 2 0 0.0035 8 0 0 0 2.28E+06 4.01E+06 - - - 1.8443 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19389.19389.2 0.0743 12-Aug K.LLDFLC[160.03]R.Q "sp|O75170|PP6R2_HUMAN,sp|Q8IZL8|PELP1_HUMAN,tr|E7EV54|E7EV54_HUMAN,tr|C9JFV4|C9JFV4_HUMAN,tr|I3L445|I3L445_HUMAN" 5 935.4899 0.47 51658 19389 2 935.491143 468.7522 Serine\threonine-protein phosphatase 6 regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PPP6R2 PE=1 SV=2 5.83 3667.9 - 370293 - - - 1.3576 - 1.702 0.307 - 172.8 1 2 0 0.0013 7 0 0 0 1.82E+06 3.87E+06 - - - 2.9932 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.19391.19391.2 0.0174 28-Aug R.VLVVGAGGIGC[160.03]ELLK.N "sp|Q9UBT2|SAE2_HUMAN,tr|U3KQ55|U3KQ55_HUMAN,tr|K7EPL2|K7EPL2_HUMAN,tr|K7ES38|K7ES38_HUMAN" 4 1483.8432 -1 51660 19391 2 1483.842107 742.9289 SUMO-activating enzyme subunit 2 OS=Homo sapiens OX=9606 GN=UBA2 PE=1 SV=2 5.97 3668.1 - 248202 - - - -0.7609 - 1.734 0.344 - 132.6 1 2 0 -0.0011 15 0 0 0 0.00E+00 0.00E+00 - - - 2.9347 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.19397.19397.2 4.86E-06 20-Oct K.VGEVTYVELFK.D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1282.6809 1.95 51664 19397 2 1282.686484 642.3477 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.53 3668.8 - 2.32E+06 - - - 4.3495 - 2.367 0.429 - 349.4 1 2 0 0.0056 11 0 0 0 4.37E+07 2.25E+07 - - - 4.5387 1 230117_WJC_METTL3_WT_vs_EV_F06.19398.19398.2 1.78E-05 17/24 R.ILDIDNVDLAMGK.M sp|O43615|TIM44_HUMAN 1 1415.733 2.59 51665 19398 2 1415.736881 708.8738 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3668.9 - 2.14E+06 - - - 2.7293 - 2.95 0.562 - 891.2 1 2 0 0.0039 13 0 0 0 1.24E+07 4.79E+06 - - - 5.9672 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.19399.19399.2 0.00706 20-Nov K.LWDLASGTLYK.E sp|O75529|TAF5L_HUMAN 1 1265.6656 1.18 51666 19399 2 1265.670133 633.8401 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 5.83 3669 - 805301 - - - 3.5902 - 1.733 0.374 - 386.5 1 2 0 0.0045 11 0 0 0 7.76E+06 6.58E+06 - - - 3.2894 1 230117_WJC_METTL3_WT_vs_EV_F06.19400.19400.2 4.05E-07 22-Dec K.VVLEGPAPWGFR.L "sp|Q9NR12|PDLI7_HUMAN,tr|D6RF83|D6RF83_HUMAN,tr|D6RAN1|D6RAN1_HUMAN,tr|H7BYK4|H7BYK4_HUMAN,tr|D6RH06|D6RH06_HUMAN" 5 1326.7085 6.27 51667 19400 2 1326.717434 664.3615 PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1 5.97 3669.2 - 4.54E+06 - - - 6.7664 - 2.306 0.575 - 433.6 1 2 0 0.009 12 0 0 0 7.12E+06 1.14E+06 - - - 5.4835 0.9955 230117_WJC_METTL3_WT_vs_EV_F06.19401.19401.2 1.15 14-Aug R.LPLFGLGR[166.11].L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 881.5362 1.42 51668 19401 2 881.539036 441.7754 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3669.3 - 626107 - - - 3.1683 - 1.497 0.186 - 306 1 2 0 0.0028 8 0 0 0 1.22E+08 8.62E+07 - - - 1.6307 0.9895 230117_WJC_METTL3_WT_vs_EV_F06.19402.19402.2 0.0409 12-Jun K.LYSLLFR[166.11].R sp|Q9UDW1|QCR9_HUMAN 1 920.5359 1.33 51669 19402 2 920.539679 461.2752 Cytochrome b-c1 complex subunit 9 OS=Homo sapiens OX=9606 GN=UQCR10 PE=1 SV=3 8.75 3669.4 - 597103 - - - 4.0954 - 1.325 0.202 - 122.3 1 2 0 0.0038 7 0 0 0 5.65E+06 4.23E+06 - - - 1.4235 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.19403.19403.2 0.00425 16-Oct K.IPSVLFLGK.L sp|Q8IW75|SPA12_HUMAN 1 972.6008 75.4 51670 19403 2 972.605492 487.3077 Serpin A12 OS=Homo sapiens OX=9606 GN=SERPINA12 PE=1 SV=1 8.75 3669.6 - 596148 - - - 4.8201 - 2.084 0.419 - 265.8 1 2 0 0.0047 9 0 0 0 4.27E+06 5.66E+04 - - - 4.2586 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.19404.19404.2 0.545 14-Oct R.LPLFGLGR.L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 871.528 1.42 51671 19404 2 871.530544 436.7713 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3669.7 - 548781 - - - 2.95 - 2.046 0.115 - 454 1 2 0 0.0026 8 0 0 0 1.22E+08 8.62E+07 - - - 2.0487 1 230117_WJC_METTL3_WT_vs_EV_F06.19406.19406.2 2.64E-07 20-Oct K.LGGNEIVSFLK[136.11].G "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 4 1183.6692 5.85 51673 19406 2 1183.672716 592.8419 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6 3670 - 419510 - - - 2.9501 - 2.37 0.527 - 187.5 1 2 0 0.0035 11 0 0 0 2.43E+07 4.16E+06 - - - 5.2666 1 230117_WJC_METTL3_WT_vs_EV_F06.19409.19409.2 0.012 22-Nov K.LFGYEPTIYYPK.R "sp|Q8NCW5|NNRE_HUMAN,tr|A0A7P0Z426|A0A7P0Z426_HUMAN,tr|Q5T3I4|Q5T3I4_HUMAN,tr|A0A7P0T9Y2|A0A7P0T9Y2_HUMAN,tr|A0A7P0TAG8|A0A7P0TAG8_HUMAN,tr|Q5T3I3|Q5T3I3_HUMAN" 6 1489.7493 -1 51676 19409 2 1489.750326 745.8819 NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2 6 3670.4 - 311338 - - - 0.676 - 2.229 0.518 - 328.6 1 2 0 0.001 12 0 0 0 0.00E+00 0.00E+00 - - - 4.9757 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19410.19410.2 5.49E-05 20-Nov K.ILEAVTLVQLK[136.11].E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1233.7788 0.87 51677 19410 2 1233.781683 617.8967 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6 3670.5 - 274853 - - - 2.357 - 2.249 0.343 - 256.5 1 2 0 0.0029 11 0 0 0 3.19E+06 3.68E+06 - - - 3.766 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.19416.19416.2 0.0776 18-Sep K.SLLFVNTLER[166.11].S "sp|Q9NY93|DDX56_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1200.6742 0.4 51682 19416 2 1200.68018 601.3444 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 5.72 3671.2 - 650871 - - - 4.9864 - 1.999 0.311 - 241.1 1 2 0 0.006 10 0 0 0 7.03E+06 1.76E+07 - - - 3.2696 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19418.19418.2 0.000415 24-Sep R.IITLAGPTNAIFK[136.11].A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1365.8111 2.77 51684 19418 2 1365.812814 683.9128 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3671.4 - 1.36E+07 - - - 1.2278 - 2.129 0.41 - 213.4 1 2 0 0.0017 13 0 0 0 4.27E+08 1.54E+08 - - - 4.0081 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19419.19419.2 0.0155 18-Oct K.AIDLFTDAIK[136.11].L "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 1113.6161 0.44 51685 19419 2 1113.617413 557.8153 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 4.21 3671.4 - 5.01E+06 - - - 1.1557 - 1.861 0.279 - 291.1 1 2 0 0.0013 10 0 0 0 1.84E+07 4.20E+07 - - - 2.835 0.9962 230117_WJC_METTL3_WT_vs_EV_F06.19420.19420.2 0.835 14-Jul K.SLLIGVFK.H "sp|Q9P2D1|CHD7_HUMAN,sp|Q9HCK8|CHD8_HUMAN,sp|Q3L8U1|CHD9_HUMAN,sp|Q8TD26|CHD6_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|H7C294|H7C294_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN,tr|A0A2R8Y840|A0A2R8Y840_HUMAN,tr|H0YJG4|H0YJG4_HUMAN" 9 875.548 4.02 51686 19420 2 875.550041 438.7813 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 8.47 3671.5 - 3.45E+06 - - - 2.2854 - 1.412 0.174 - 165.6 1 2 0 0.002 8 0 0 0 1.51E+07 3.75E+06 - - - 1.3661 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19421.19421.2 1.21E-06 16-Oct K.WQALLVQIR.K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1125.6659 1.11 51687 19421 2 1125.66729 563.8402 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.75 3671.5 - 2.40E+06 - - - 1.2668 - 2.111 0.403 - 449.5 1 2 0 0.0014 9 0 0 0 6.66E+06 6.01E+06 - - - 4.1787 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19422.19422.2 0.064 16-Nov K.WQALLVQIR[166.11].K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1135.6741 1.8 51688 19422 2 1135.675232 568.8443 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.75 3671.6 - 2.33E+06 - - - 0.9668 - 2.091 0.375 - 550 1 2 0 0.0011 9 0 0 0 1.12E+07 6.24E+06 - - - 3.9444 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19423.19423.2 5.63E-05 16-Sep K.DVDLEFLAK[136.11].M "sp|P55072|TERA_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN" 6 1056.5583 0.78 51689 19423 2 1056.560144 529.2864 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.03 3671.6 - 2.21E+06 - - - 1.7671 - 1.777 0.329 - 205.1 1 2 0 0.0019 9 0 0 0 5.16E+06 6.63E+06 - - - 3.1337 1 230117_WJC_METTL3_WT_vs_EV_F06.19424.19424.2 1.00E-06 20-Dec K.LWDLASGTLYK[136.11].E sp|O75529|TAF5L_HUMAN 1 1273.6798 1.18 51690 19424 2 1273.682249 637.8472 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 5.83 3671.7 - 1.80E+06 - - - 1.9314 - 2.364 0.539 - 491.8 1 2 0 0.0025 11 0 0 0 7.76E+06 6.58E+06 - - - 5.3487 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19425.19425.2 0.0138 22-Aug K.LILISTNGSFIR[166.11].L sp|Q6UXN9|WDR82_HUMAN 1 1342.7848 0.79 51691 19425 2 1342.787466 672.3997 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 9.75 3671.8 - 1.65E+06 - - - 1.981 - 1.857 0.305 - 172.8 1 2 0 0.0027 12 0 0 0 5.39E+06 6.82E+06 - - - 2.9215 0.9629 230117_WJC_METTL3_WT_vs_EV_F06.19426.19426.2 1.69 26-Jul K.VVIGMDVAASEFYR.N "sp|P13929|ENOB_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN" 2 1555.7705 2.13 51692 19426 2 1555.772166 778.8925 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.37 3671.9 - 1.50E+06 - - - 1.0933 - 1.09 0.047 - 103.2 1 2 0 0.0017 14 0 0 0 4.06E+07 1.91E+07 - - - -0.3961 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19427.19427.2 0.002 16-Aug R.MADLSELLK[136.11].E "sp|P30519|HMOX2_HUMAN,tr|I3L276|I3L276_HUMAN,tr|I3L159|I3L159_HUMAN,tr|I3L463|I3L463_HUMAN,tr|I3L4P8|I3L4P8_HUMAN,tr|A0A1B0GXH0|A0A1B0GXH0_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 8 1026.5511 -1 51693 19427 2 1026.551802 514.2828 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 4.37 3672 - 983975 - - - 0.7004 - 1.814 0.331 - 153.3 1 2 0 0.0007 9 0 0 0 0.00E+00 0.00E+00 - - - 3.2085 0.9623 230117_WJC_METTL3_WT_vs_EV_F06.19428.19428.2 2.51 26-Jun K.VVIGMDVAASEFYR[166.11].N "sp|P13929|ENOB_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN" 2 1565.7787 2.13 51694 19428 2 1565.782491 783.8966 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.37 3672.1 - 722186 - - - 2.3988 - 0.983 0.103 - 72.8 1 2 0 0.0038 14 0 0 0 4.06E+07 1.91E+07 - - - -0.2424 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19430.19430.2 0.00012 18-Sep R.VLALEILPER[166.11].V sp|Q56A73|SPIN4_HUMAN 1 1161.6997 0.43 51696 19430 2 1161.70097 581.8571 Spindlin-4 OS=Homo sapiens OX=9606 GN=SPIN4 PE=1 SV=1 4.53 3672.4 - 577756 - - - 1.1104 - 2.16 0.437 - 294.3 1 2 0 0.0013 10 0 0 0 2.02E+06 4.64E+06 - - - 4.4179 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.19431.19431.2 2.26 12-Aug K.FDLIWNR.A "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|H0YEW4|H0YEW4_HUMAN,tr|A8MRA7|A8MRA7_HUMAN,tr|H0YD21|H0YD21_HUMAN" 5 962.4974 1.81 51697 19431 2 962.498345 482.256 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 5.84 3672.5 - 530683 - - - 0.9808 - 1.858 0.201 - 296 1 2 0 0.0009 7 0 0 0 1.90E+06 1.05E+06 - - - 2.4882 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19440.19440.2 0.00157 18-Oct K.AVQFFVQALR.M "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 14 1177.6608 1.46 51705 19440 2 1177.664681 589.8377 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 9.79 3673.6 - 2.86E+06 - - - 3.3142 - 2.16 0.412 - 472.2 1 2 0 0.0039 10 0 0 0 2.13E+07 1.46E+07 - - - 4.2324 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.19441.19441.2 0.641 14-Sep R.EMVLEIIR.E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1001.558 1.9 51706 19441 2 1001.561281 501.7863 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3673.8 - 2.05E+06 - - - 3.3228 - 1.987 0.168 - 375.5 1 2 0 0.0033 8 0 0 0 2.14E+07 1.13E+07 - - - 2.3516 0.9795 230117_WJC_METTL3_WT_vs_EV_F06.19442.19442.2 0.188 14-Jun K.GVLSDLTK.V "sp|Q8NG11|TSN14_HUMAN,tr|A6NEP9|A6NEP9_HUMAN,tr|H7BXY6|H7BXY6_HUMAN" 3 831.4702 3.76 51707 19442 2 831.472759 416.7424 Tetraspanin-14 OS=Homo sapiens OX=9606 GN=TSPAN14 PE=1 SV=1 5.84 3673.9 - 997891 - - - 3.0981 - 1.348 0.066 - 109.5 1 2 0 0.0026 8 0 0 0 5.21E+06 1.39E+06 - - - 0.4283 0.883 230117_WJC_METTL3_WT_vs_EV_F06.19443.19443.2 0.127 12-Jul R.YVLSFLR.T "sp|Q96SI1|KCD15_HUMAN,tr|V9GYY8|V9GYY8_HUMAN,tr|K7EN63|K7EN63_HUMAN" 3 896.512 4.55 51708 19443 2 896.51681 449.2633 BTB\POZ domain-containing protein KCTD15 OS=Homo sapiens OX=9606 GN=KCTD15 PE=1 SV=1 8.75 3674 - 781892 - - - 5.3775 - 1.393 0.018 - 157.1 1 2 0 0.0048 7 0 0 0 4.24E+06 9.32E+05 - - - 0.2227 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19445.19445.2 0.000392 22-Sep K.QVVPFVYQTIVK[136.11].D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1427.8268 1.8 51710 19445 2 1427.831289 714.9207 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 3674.3 - 513435 - - - 3.1523 - 1.819 0.472 - 145.6 1 2 0 0.0045 12 0 0 0 4.19E+06 2.33E+06 - - - 4.1 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.19447.19447.2 1.97E-06 22-Aug K.LFGYEPTIYYPK[136.11].R "sp|Q8NCW5|NNRE_HUMAN,tr|A0A7P0Z426|A0A7P0Z426_HUMAN,tr|Q5T3I4|Q5T3I4_HUMAN,tr|A0A7P0T9Y2|A0A7P0T9Y2_HUMAN,tr|A0A7P0TAG8|A0A7P0TAG8_HUMAN,tr|Q5T3I3|Q5T3I3_HUMAN" 6 1497.7635 -1 51712 19447 2 1497.770388 749.889 NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2 6 3674.5 - 428397 - - - 4.5862 - 1.944 0.495 - 143.1 1 2 0 0.0069 12 0 0 0 0.00E+00 0.00E+00 - - - 4.444 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19455.19455.2 1.67E-05 24-Jul K.LVDSMGWELASVR.R "sp|O94761|RECQ4_HUMAN,tr|A0A087WTJ0|A0A087WTJ0_HUMAN,tr|A0A087X072|A0A087X072_HUMAN" 3 1461.7286 1.28 51720 19455 2 1461.729747 731.8716 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.37 3675.6 - 118875 - - - 0.7847 - 1.829 0.444 - 116.7 1 2 0 0.0011 13 0 0 0 2.45E+06 1.91E+06 - - - 3.8696 1 230117_WJC_METTL3_WT_vs_EV_F06.19458.19458.2 1.01E-05 20-Sep K.VGEVTYVELFK[136.11].D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1290.6951 1.95 51722 19458 2 1290.698714 646.3548 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.53 3675.8 - 1.67E+06 - - - 2.7962 - 2.273 0.572 - 302.3 1 2 0 0.0036 11 0 0 0 4.37E+07 2.25E+07 - - - 5.4859 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19460.19460.2 0.0326 16-Aug K.NLLNLDVIK[136.11].K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1048.6372 0.99 51724 19460 2 1048.639054 525.3259 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3675.9 - 2.85E+06 - - - 1.7718 - 1.766 0.291 - 197 1 2 0 0.0019 9 0 0 0 3.10E+07 3.12E+07 - - - 2.8351 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.19461.19461.2 0.432 16-Aug K.NLLNLDVIK.K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1040.623 0.99 51725 19461 2 1040.624954 521.3188 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3675.9 - 2.48E+06 - - - 1.8816 - 1.53 0.192 - 209.5 1 2 0 0.002 9 0 0 0 3.10E+07 3.12E+07 - - - 1.6888 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19462.19462.2 0.0087 14-Sep R.LWDFIENR.E "sp|Q9H000|MKRN2_HUMAN,tr|A0A7I2V5D2|A0A7I2V5D2_HUMAN,tr|A0A7I2YQI0|A0A7I2YQI0_HUMAN,tr|C9J494|C9J494_HUMAN" 4 1091.54 2.51 51726 19462 2 1091.542287 546.7773 Probable E3 ubiquitin-protein ligase makorin-2 OS=Homo sapiens OX=9606 GN=MKRN2 PE=1 SV=2 4.37 3676 - 683068 - - - 2.1007 - 1.928 0.354 - 327.1 1 2 0 0.0023 8 0 0 0 8.31E+06 3.31E+06 - - - 3.6348 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19467.19467.2 0.0104 16-Sep R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 2.32 51731 19467 2 1006.572179 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3676.5 - 256453 - - - 2.2661 - 1.769 0.399 - 209.9 1 2 0 0.0023 9 0 0 0 3.32E+06 1.43E+06 - - - 3.6375 1 230117_WJC_METTL3_WT_vs_EV_F06.19468.19468.2 0.000105 20-Nov K.ILEAVTLVQLK.E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1225.7646 0.87 51732 19468 2 1225.763245 613.8896 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6 3676.6 - 234466 - - - -1.085 - 2.317 0.517 - 263.6 1 2 0 -0.0013 11 0 0 0 3.19E+06 3.68E+06 - - - 5.1323 1 230117_WJC_METTL3_WT_vs_EV_F06.19473.19473.2 0.00103 22-Dec R.LLTWVIGTGSPR[166.11].L sp|Q92616|GCN1_HUMAN 1 1308.7429 1.14 51735 19473 2 1308.746937 655.3787 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.75 3677.2 - 305552 - - - 3.0525 - 2.457 0.505 - 616.2 1 2 0 0.004 12 0 0 0 8.17E+06 7.17E+06 - - - 5.1349 0.9932 230117_WJC_METTL3_WT_vs_EV_F06.19474.19474.2 8.24E-05 20-Oct R.LLESLDQLELR.V sp|O95816|BAG2_HUMAN 1 1327.7347 8.84 51736 19474 2 1327.743641 664.8746 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.14 3677.3 - 248590 - - - 6.7107 - 2.288 0.372 - 350.1 1 2 0 0.0089 11 0 0 0 1.82E+08 2.06E+07 - - - 4.0249 1 230117_WJC_METTL3_WT_vs_EV_F06.19477.19477.2 8.20E-07 13/26 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 3.33 51739 19477 2 1541.84618 771.9299 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3677.7 - 85377.7 - - - 0.5422 - 2.803 0.439 - 644.5 1 2 0 0.0008 14 0 0 0 8.96E+07 2.69E+07 - - - 4.8697 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.19484.19484.2 0.00311 28-Aug R.VGPDVVTDPAFLVTR.S sp|Q9NV31|IMP3_HUMAN 1 1584.8512 1.45 51744 19484 2 1584.855667 793.4329 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3678.7 - 368498 - - - 2.8451 - 1.727 0.364 - 169.8 1 2 0 0.0045 15 0 0 0 8.21E+06 5.66E+06 - - - 3.0714 1 230117_WJC_METTL3_WT_vs_EV_F06.19486.19486.2 1.25E-07 14/28 R.VGPDVVTDPAFLVTR[166.11].S sp|Q9NV31|IMP3_HUMAN 1 1594.8594 1.45 51746 19486 2 1594.863145 798.437 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3678.9 - 234920 - - - 2.3306 - 2.126 0.582 - 466.7 1 2 0 0.0037 15 0 0 0 8.21E+06 5.66E+06 - - - 5.1928 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.19487.19487.2 6.44E-05 24-Sep R.VESPVLPPVLVPR[166.11].H "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN" 2 1410.8474 2.23 51747 19487 2 1410.853516 706.431 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 5.97 3679.1 - 227721 - - - 4.33 - 1.939 0.488 - 186.1 1 2 0 0.0061 13 0 0 0 6.96E+06 3.13E+06 - - - 4.3429 0.8576 230117_WJC_METTL3_WT_vs_EV_F06.19489.19489.2 1.11 20-Jul R.KDVSYYIAC[160.03]K[136.11]K.C "sp|P54756|EPHA5_HUMAN,tr|B7ZKW7|B7ZKW7_HUMAN,tr|F8VP57|F8VP57_HUMAN,tr|B7ZKJ3|B7ZKJ3_HUMAN" 4 1381.7155 - 51749 19489 2 1381.725845 691.865 Ephrin type-A receptor 5 OS=Homo sapiens OX=9606 GN=EPHA5 PE=1 SV=3 9.05 3679.3 - 196307 - - - 7.4704 - 1.377 0.147 - 141.9 1 2 0 0.0103 11 0 0 0 - - - - - 0.9889 1 230117_WJC_METTL3_WT_vs_EV_F06.19490.19490.2 1.20E-08 24-Nov K.LVDSMGWELASVR[166.11].R "sp|O94761|RECQ4_HUMAN,tr|A0A087WTJ0|A0A087WTJ0_HUMAN,tr|A0A087X072|A0A087X072_HUMAN" 3 1471.7369 1.33 51750 19490 2 1471.742101 736.8757 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.37 3679.5 - 163249 - - - 3.5543 - 2.455 0.6 - 371.7 1 2 0 0.0052 13 0 0 0 2.54E+06 1.91E+06 - - - 5.776 1 230117_WJC_METTL3_WT_vs_EV_F06.19491.19491.2 6.18E-06 22-Oct R.ELYLEDSPLELK.L sp|Q8TEM1|PO210_HUMAN 1 1447.7446 3.03 51751 19491 2 1447.748786 724.8796 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4 3679.6 - 156680 - - - 2.8727 - 2.146 0.495 - 236 1 2 0 0.0042 12 0 0 0 4.55E+06 1.50E+06 - - - 4.7049 0.9865 230117_WJC_METTL3_WT_vs_EV_F06.19495.19495.2 0.383 22-Jul R.SQPAILLLTAAR.D "sp|Q5JTV8|TOIP1_HUMAN,tr|H0Y4R4|H0Y4R4_HUMAN,tr|J3KN66|J3KN66_HUMAN,tr|A0A0A0MSK5|A0A0A0MSK5_HUMAN" 4 1252.7503 1.74 51755 19495 2 1252.754328 627.3824 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=2 9.47 3680.1 - 84447 - - - 3.1978 - 1.395 0.116 - 130.3 1 2 0 0.004 12 0 0 0 4.09E+06 2.35E+06 - - - 0.7724 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.19502.19502.2 0.0115 12-Jun R.EFEFLMR.Q sp|P85037|FOXK1_HUMAN 1 970.4582 2.64 51760 19502 2 970.458352 486.2364 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 4.53 3680.7 - 220321 - - - 0.1164 - 1.248 0.242 - 125.5 1 2 0 0.0001 7 0 0 0 3.56E+06 1.35E+06 - - - 1.5303 1 230117_WJC_METTL3_WT_vs_EV_F06.19504.19504.2 2.05E-06 13/20 K.IDAELVLPTIR.S "sp|O95985|TOP3B_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 2 1238.7234 0.74 51762 19504 2 1238.725895 620.369 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 4.37 3681 - 63019.6 - - - 1.9835 - 2.778 0.47 - 522.3 1 2 0 0.0025 11 0 0 0 2.51E+06 3.40E+06 - - - 5.2757 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19510.19510.2 0.00022 20-Oct R.LLESLDQLELR[166.11].V sp|O95816|BAG2_HUMAN 1 1337.743 8.84 51766 19510 2 1337.746666 669.8788 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.14 3681.7 - 638006 - - - 2.7397 - 2.177 0.392 - 287.9 1 2 0 0.0037 11 0 0 0 1.82E+08 2.06E+07 - - - 4.0397 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19511.19511.2 0.00018 18-Nov R.LIESLFTIQK[136.11].M "sp|Q12789|TF3C1_HUMAN,tr|H3BU37|H3BU37_HUMAN" 2 1198.7053 1.71 51767 19511 2 1198.709289 600.3599 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 6 3681.9 - 420182 - - - 3.3486 - 2.008 0.42 - 275.7 1 2 0 0.004 10 0 0 0 1.04E+07 6.09E+06 - - - 4.0878 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19515.19515.2 0.00605 20-Nov R.VLITTLITAGR[166.11].L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1166.7262 0.9 51771 19515 2 1166.726866 584.3704 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3682.4 - 168910 - - - 0.546 - 2.236 0.391 - 292.9 1 2 0 0.0006 11 0 0 0 8.24E+06 9.14E+06 - - - 4.1056 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19520.19520.2 0.312 18-Nov R.AEVVSLLLDR[166.11].K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1123.6476 1.14 51775 19520 2 1123.64976 562.8311 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3682.9 - 4.54E+06 - - - 1.8832 - 2.112 0.326 - 620.9 1 2 0 0.0021 10 0 0 0 4.54E+07 3.99E+07 - - - 3.535 1 230117_WJC_METTL3_WT_vs_EV_F06.19521.19521.2 5.78E-07 18/26 K.LLDAVDTYIPVPAR[166.11].D sp|P49411|EFTU_HUMAN 1 1551.8536 3.33 51776 19521 2 1551.856401 776.9341 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3683 - 1.48E+06 - - - 1.7959 - 3.008 0.607 - 1202.6 1 2 0 0.0028 14 0 0 0 8.96E+07 2.69E+07 - - - 6.287 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19523.19523.2 0.000294 16-Sep K.GLMVLELPK.R "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 998.5834 2.53 51778 19523 2 998.585417 500.299 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6 3683.2 - 747797 - - - 1.9808 - 1.716 0.366 - 304.9 1 2 0 0.002 9 0 0 0 5.81E+06 2.29E+06 - - - 3.3059 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19527.19527.2 0.000146 20-Nov R.VLITTLITAGR.L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1156.718 0.9 51782 19527 2 1156.720775 579.3663 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3683.7 - 491455 - - - 2.4345 - 2.311 0.365 - 327.2 1 2 0 0.0028 11 0 0 0 8.24E+06 9.14E+06 - - - 4.0021 0.9914 230117_WJC_METTL3_WT_vs_EV_F06.19528.19528.2 0.866 14-Jul R.TLTDLLLR.F "sp|O76024|WFS1_HUMAN,tr|A0A669KAX3|A0A669KAX3_HUMAN,tr|H0Y9G5|H0Y9G5_HUMAN" 3 943.5702 1.25 51783 19528 2 943.571372 472.7924 Wolframin OS=Homo sapiens OX=9606 GN=WFS1 PE=1 SV=2 5.5 3683.9 - 276531 - - - 1.2082 - 1.328 0.092 - 124.5 1 2 0 0.0011 8 0 0 0 1.84E+06 1.48E+06 - - - 0.5757 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19531.19531.2 0.00125 26-Oct R.LIVVLEGASLETVK[136.11].V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1477.8847 0.83 51786 19531 2 1477.884989 739.9496 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3684.3 - 138883 - - - 0.1983 - 2.312 0.316 - 257.3 1 2 0 0.0003 14 0 0 0 1.98E+06 2.39E+06 - - - 3.4781 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19534.19534.2 0.0157 18-Oct R.EALLAALGYK[136.11].N sp|Q9BU76|MMTA2_HUMAN 1 1055.6106 0.92 51788 19534 2 1055.610284 528.8126 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3684.6 - 1.81E+06 - - - -0.3439 - 2.265 0.302 - 299.7 1 2 0 -0.0004 10 0 0 0 1.92E+07 2.08E+07 - - - 3.5536 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.19536.19536.3 0.00298 Dec-52 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 3.5 51789 19536 3 1541.847917 514.9557 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3684.8 - 354738 - - - 1.6688 - 2.247 0.421 - 115.4 1 2 0 0.0026 14 0 0 0 1.10E+07 3.15E+06 - - - 5.3845 0.9725 230117_WJC_METTL3_WT_vs_EV_F06.19539.19539.2 2.54 18-May K.IELFADVVPK[136.11].T "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 1137.6525 3.1 51792 19539 2 1137.656209 569.8335 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.37 3685 - 1.15E+06 - - - 3.2506 - 1.148 0.168 - 42.8 7 2 0 0.0037 10 0 0 0 6.18E+07 2.00E+07 - - - 0.2884 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.19540.19540.2 0.0194 16-Sep K.TFDPYIIIR[166.11].A sp|Q13601|KRR1_HUMAN 1 1146.6313 0.58 51793 19540 2 1146.63284 574.3229 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 5.5 3685 - 1.14E+06 - - - 1.3727 - 1.68 0.144 - 266.5 1 2 0 0.0016 9 0 0 0 1.01E+07 1.72E+07 - - - 1.605 0.9848 230117_WJC_METTL3_WT_vs_EV_F06.19543.19543.2 2.06 12-Jun R.AFLPLLK.A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 800.516 1.27 51796 19543 2 800.516628 401.2653 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3685.3 - 310343 - - - 0.7708 - 1.185 0.089 - 182.6 1 2 0 0.0006 7 0 0 0 1.03E+07 8.16E+06 - - - 0.236 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.19545.19545.2 6.52E-05 20-Oct K.VAPGFQFFATR.R sp|Q9NU22|MDN1_HUMAN 1 1239.64 1.07 51798 19545 2 1239.646485 620.8273 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 9.72 3685.5 - 291846 - - - 5.1967 - 1.592 0.473 - 257.9 1 2 0 0.0064 11 0 0 0 2.99E+06 2.78E+06 - - - 3.7905 0.8966 230117_WJC_METTL3_WT_vs_EV_F06.19553.19553.2 2.47 14-May R.VPGTLLPR[166.11].L sp|Q96BJ3|AIDA_HUMAN 1 861.5312 1.22 51805 19553 2 861.532117 431.7729 "Axin interactor, dorsalization-associated protein OS=Homo sapiens OX=9606 GN=AIDA PE=1 SV=1" 9.72 3686.5 - 2.68E+06 - - - 1.1131 - 1.032 0.019 - 119.3 6 2 0 0.001 8 0 0 0 2.64E+07 2.16E+07 - - - -1.0716 0.9905 230117_WJC_METTL3_WT_vs_EV_F06.19556.19556.2 0.0331 12-Jun R.EAYFWLR[166.11].Q sp|Q8TCJ2|STT3B_HUMAN 1 993.4948 1.02 51808 19556 2 993.500022 497.7547 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1 6.1 3686.9 - 456957 - - - 5.2844 - 1.29 0.327 - 116.7 1 2 0 0.0053 7 0 0 0 2.79E+06 2.74E+06 - - - 2.2614 0.9959 230117_WJC_METTL3_WT_vs_EV_F06.19557.19557.2 0.018 12-Aug R.FANYIDK.V "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 869.4283 0.86 51809 19557 2 869.431825 435.7214 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.83 3687 - 428046 - - - 4.0325 - 1.546 0.248 - 182.1 1 2 0 0.0035 7 0 0 0 3.24E+06 3.78E+06 - - - 2.2521 0.8809 230117_WJC_METTL3_WT_vs_EV_F06.19559.19559.2 1.98 20-Aug K.IAVDELFTSLR.D sp|Q8WU76|SCFD2_HUMAN 1 1262.6871 10.44 51811 19559 2 1262.692401 632.3508 Sec1 family domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SCFD2 PE=1 SV=2 4.37 3687.2 - 393289 - - - 4.2354 - 1.016 0.102 - 82.9 2 2 0 0.0053 11 0 0 0 1.56E+07 1.50E+06 - - - -0.2988 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.19560.19560.2 0.000317 20-Sep K.VAPGFQFFATR[166.11].R sp|Q9NU22|MDN1_HUMAN 1 1249.6483 1.08 51812 19560 2 1249.654099 625.8314 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 9.72 3687.4 - 347618 - - - 4.6301 - 1.555 0.413 - 269.8 1 2 0 0.0058 11 0 0 0 2.84E+06 2.63E+06 - - - 3.2839 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.19562.19562.2 0.0843 12-Jul R.FANYIDK[136.11].V "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 877.4425 0.86 51814 19562 2 877.446071 439.7285 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.83 3687.6 - 321191 - - - 4.0481 - 1.496 0.29 - 128.2 1 2 0 0.0036 7 0 0 0 3.24E+06 3.78E+06 - - - 2.4581 1 230117_WJC_METTL3_WT_vs_EV_F06.19563.19563.2 1.21E-05 18-Oct K.LFGYEMAEFK.V sp|Q9UKD2|MRT4_HUMAN 1 1233.574 -1 51815 19563 2 1233.578089 617.7943 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 4.53 3687.8 - 284637 - - - 3.3172 - 2.093 0.542 - 219.7 1 2 0 0.0041 10 0 0 0 0.00E+00 0.00E+00 - - - 5.1046 1 230117_WJC_METTL3_WT_vs_EV_F06.19564.19564.2 7.94E-05 14/26 R.LIVVLEGASLETVK.V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1469.8705 0.83 51816 19564 2 1469.875309 735.9425 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3687.9 - 229104 - - - 3.2744 - 2.898 0.505 - 593.6 1 2 0 0.0048 14 0 0 0 1.98E+06 2.39E+06 - - - 5.4395 0.9968 230117_WJC_METTL3_WT_vs_EV_F06.19568.19568.2 0.0219 18-Sep R.EALLAALGYK.N sp|Q9BU76|MMTA2_HUMAN 1 1047.5964 0.65 51819 19568 2 1047.601994 524.8055 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3688.5 - 8.47E+06 - - - 5.295 - 2.145 0.337 - 208.2 1 2 0 0.0055 10 0 0 0 2.01E+07 3.06E+07 - - - 3.6585 0.9898 230117_WJC_METTL3_WT_vs_EV_F06.19571.19571.2 0.431 12-Jun R.AFLPLLK[136.11].A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 808.5302 1.27 51822 19571 2 808.531677 405.2724 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3688.7 - 3.16E+06 - - - 1.8132 - 1.323 0.077 - 193 1 2 0 0.0015 7 0 0 0 1.03E+07 8.16E+06 - - - 0.4961 0.999 230117_WJC_METTL3_WT_vs_EV_F06.19572.19572.2 7.95E-05 18-Sep K.LFGYEMAEFK[136.11].V sp|Q9UKD2|MRT4_HUMAN 1 1241.5882 0.76 51823 19572 2 1241.592657 621.8014 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 4.53 3688.8 - 2.01E+06 - - - 3.5922 - 1.597 0.458 - 201.6 1 2 0 0.0045 10 0 0 0 2.87E+06 3.77E+06 - - - 3.7291 1 230117_WJC_METTL3_WT_vs_EV_F06.19573.19573.2 1.42E-06 22-Nov K.VIHDNFGIVEGL.M "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1311.6823 - 51824 19573 2 1311.68438 656.8484 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.35 3688.9 - 1.67E+06 - - - 1.5842 - 2.559 0.484 - 480.3 1 1 0 0.0021 12 0 0 0 - - - - - 5.0875 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.19577.19577.2 0.0218 13/20 R.LALVISELEGK[136.11].A "sp|Q12899|TRI26_HUMAN,tr|A2AE48|A2AE48_HUMAN" 2 1178.7002 1.42 51828 19577 2 1178.70555 590.3574 Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1 4.53 3689.4 - 973603 - - - 4.5474 - 2.611 0.333 - 554.9 1 2 0 0.0054 11 0 0 0 4.35E+06 3.07E+06 - - - 4.0952 1 230117_WJC_METTL3_WT_vs_EV_F06.19578.19578.2 2.77E-06 22-Nov K.VLLSPDYLPAMR.R sp|Q7Z6Z7|HUWE1_HUMAN 1 1373.7377 1.8 51829 19578 2 1373.741987 687.8761 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.81 3689.5 - 887920 - - - 3.1149 - 2.25 0.554 - 406.2 1 2 0 0.0043 12 0 0 0 5.57E+06 3.10E+06 - - - 5.2652 0.9939 230117_WJC_METTL3_WT_vs_EV_F06.19580.19580.2 0.435 14-Jul R.YELALILK[136.11].A sp|P82932|RT06_HUMAN 1 969.599 2.55 51831 19580 2 969.600127 485.8068 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3689.8 - 845237 - - - 1.1427 - 1.37 0.143 - 114.6 3 2 0 0.0011 8 0 0 0 1.20E+07 4.72E+06 - - - 0.8332 1 230117_WJC_METTL3_WT_vs_EV_F06.19582.19582.2 7.30E-09 26-Dec K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 3.07 51833 19582 2 1762.800847 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3690 - 536271 - - - 3.2602 - 2.281 0.664 - 446.8 1 2 0 0.0057 14 0 0 0 2.27E+06 7.40E+05 - - - 6.0128 0.999 230117_WJC_METTL3_WT_vs_EV_F06.19583.19583.2 0.00429 14-Aug K.DFAIDIIK.S sp|Q15181|IPYR_HUMAN 1 933.5171 2.81 51834 19583 2 933.518654 467.7658 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 4.21 3690.1 - 476562 - - - 1.6283 - 1.322 0.341 - 177.7 1 2 0 0.0015 8 0 0 0 1.35E+06 4.80E+05 - - - 2.401 0.978 230117_WJC_METTL3_WT_vs_EV_F06.19585.19585.2 0.873 24-Jul R.TLGLC[160.03]GTFNGNIR.D "sp|Q3ZCN5|OTOGL_HUMAN,tr|A0A2R8YF04|A0A2R8YF04_HUMAN" 2 1421.7085 999 51836 19585 2 1421.713476 711.8615 Otogelin-like protein OS=Homo sapiens OX=9606 GN=OTOGL PE=1 SV=5 7.91 3690.4 - 382814 - - - 3.4768 - 1.303 0.112 - 97.5 1 2 0 0.0049 13 0 0 0 2.11E+06 0.00E+00 - - - 0.546 1 230117_WJC_METTL3_WT_vs_EV_F06.19586.19586.2 1.41E-06 13/26 K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 3.07 51837 19586 2 1772.812454 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3690.5 - 249462 - - - 5.1241 - 2.553 0.655 - 568.4 1 2 0 0.0091 14 0 0 0 2.27E+06 7.40E+05 - - - 6.228 1 230117_WJC_METTL3_WT_vs_EV_F06.19590.19590.2 0.000717 18-Sep R.AEVVSLLLDR.K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1113.6394 1.14 51840 19590 2 1113.644455 557.827 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3691 - 743021 - - - 4.5625 - 2.197 0.462 - 363.4 1 2 0 0.0051 10 0 0 0 4.54E+07 3.99E+07 - - - 4.6488 0.9935 230117_WJC_METTL3_WT_vs_EV_F06.19591.19591.2 0.000336 13/18 R.IINDLLQSLR.S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1183.6925 2.19 51841 19591 2 1183.698726 592.8535 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3691 - 9.44E+06 - - - 5.2835 - 2.422 0.157 - 553.8 1 2 0 0.0063 10 0 0 0 1.30E+08 5.96E+07 - - - 2.6678 0.9962 230117_WJC_METTL3_WT_vs_EV_F06.19592.19592.2 1.18 18-Dec R.IINDLLQSLR[166.11].S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1193.7007 2.18 51842 19592 2 1193.705955 597.8576 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3691.1 - 5.04E+06 - - - 4.3671 - 2.291 0.165 - 374.7 1 2 0 0.0052 10 0 0 0 1.30E+08 5.94E+07 - - - 2.572 0.996 230117_WJC_METTL3_WT_vs_EV_F06.19594.19594.2 0.000825 18-Oct K.IELFADVVPK.T "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 1129.6383 1.36 51844 19594 2 1129.644745 565.8264 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.37 3691.2 - 3.42E+06 - - - 5.6956 - 2.121 0.356 - 250.2 1 2 0 0.0064 10 0 0 0 7.15E+07 5.26E+07 - - - 3.7671 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.19596.19596.2 0.000339 14-Nov R.YELALILK.A sp|P82932|RT06_HUMAN 1 961.5848 2.55 51846 19596 2 961.589279 481.7997 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3691.4 - 1.85E+06 - - - 4.6382 - 1.915 0.386 - 339.2 1 2 0 0.0045 8 0 0 0 1.20E+07 4.72E+06 - - - 3.8501 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.19597.19597.2 0.00128 20-Dec R.LALVISELEGK.A "sp|Q12899|TRI26_HUMAN,tr|A2AE48|A2AE48_HUMAN" 2 1170.686 1.42 51847 19597 2 1170.692406 586.3503 Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1 4.53 3691.6 - 965326 - - - 5.4805 - 2.471 0.364 - 395.4 1 2 0 0.0064 11 0 0 0 4.35E+06 3.07E+06 - - - 4.1747 1 230117_WJC_METTL3_WT_vs_EV_F06.19601.19601.2 0.00014 14/22 R.IEGVLLLGEPVR.W "sp|Q9BXW7|HDHD5_HUMAN,tr|A8MYZ9|A8MYZ9_HUMAN" 2 1293.7656 3.28 51851 19601 2 1293.769367 647.8901 Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Homo sapiens OX=9606 GN=HDHD5 PE=1 SV=1 4.53 3692.1 - 473114 - - - 2.8831 - 2.706 0.439 - 1059.3 1 2 0 0.0037 12 0 0 0 4.17E+06 1.27E+06 - - - 4.9015 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.19605.19605.2 0.00157 18-Sep R.VIVVWFQNAR.Q "sp|Q86UP3|ZFHX4_HUMAN,sp|Q15911|ZFHX3_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 3 1230.6873 0.87 51855 19605 2 1230.693198 616.3509 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 9.72 3692.6 - 306380 - - - 4.7705 - 1.691 0.413 - 215.6 1 2 0 0.0059 10 0 0 0 6.65E+06 7.68E+06 - - - 3.5559 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19607.19607.2 0.00219 14-Sep R.NYFGLFPR[166.11].V sp|Q8WUF5|IASPP_HUMAN 1 1022.5213 1.57 51857 19607 2 1022.524197 512.2679 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.75 3692.9 - 286578 - - - 2.8127 - 1.651 0.39 - 274.3 1 2 0 0.0029 8 0 0 0 1.60E+07 1.02E+07 - - - 3.4328 0.9629 230117_WJC_METTL3_WT_vs_EV_F06.19611.19611.2 0.515 24-Jul R.IITLAGPTNAIFK.A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1357.7969 8.76 51860 19611 2 1357.803656 679.9057 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3693.4 - 109727 - - - 4.9485 - 1.448 0.121 - 148.4 1 2 0 0.0067 13 0 0 0 8.91E+05 1.02E+05 - - - 0.8827 0.9865 230117_WJC_METTL3_WT_vs_EV_F06.19617.19617.2 0.231 16-Apr R.GWAPVFLDR.E "sp|Q9Y5Y2|NUBP2_HUMAN,tr|H3BQR2|H3BQR2_HUMAN,tr|H3BRE1|H3BRE1_HUMAN,tr|H3BNF0|H3BNF0_HUMAN,tr|H3BNS4|H3BNS4_HUMAN" 5 1059.5502 3.93 51866 19617 2 1059.552117 530.7824 Cytosolic Fe-S cluster assembly factor NUBP2 OS=Homo sapiens OX=9606 GN=NUBP2 PE=1 SV=1 5.84 3693.7 - 1.14E+06 - - - 1.8423 - 1.323 0.148 - 37.5 27 2 0 0.002 9 0 0 0 9.19E+06 2.34E+06 - - - 0.3039 1 230117_WJC_METTL3_WT_vs_EV_F06.19620.19620.2 0.000156 18-Nov R.LGLEDFESLK[136.11].V sp|Q15208|STK38_HUMAN 1 1157.606 0.55 51869 19620 2 1157.607964 579.8103 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3693.9 - 833667 - - - 1.7355 - 2.508 0.482 - 293.6 1 2 0 0.002 10 0 0 0 1.60E+08 2.94E+08 - - - 5.167 0.9658 230117_WJC_METTL3_WT_vs_EV_F06.19627.19627.2 0.535 16-May K.LQLSLADFR[166.11].R "sp|O00541|PESC_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 2 1071.5952 0.97 51874 19627 2 1071.601126 536.8049 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 5.84 3694.7 - 697303 - - - 5.5161 - 1.234 0.234 - 82.9 2 2 0 0.0059 9 0 0 0 1.86E+07 1.93E+07 - - - 1.2413 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.19628.19628.2 0.00791 18-Oct R.IEGLLAAFPK[136.11].L "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|E9PK34|E9PK34_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 4 1065.6314 2.22 51875 19628 2 1065.636081 533.823 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6 3694.7 - 1.11E+06 - - - 4.4096 - 1.921 0.308 - 244.9 1 2 0 0.0047 10 0 0 0 2.84E+07 1.28E+07 - - - 3.1367 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19638.19638.2 0.00191 18-Jul R.LGLEDFESLK.V sp|Q15208|STK38_HUMAN 1 1149.5918 0.55 51883 19638 2 1149.592198 575.8032 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3695.8 - 409252 - - - 0.3854 - 1.662 0.491 - 108.9 1 2 0 0.0004 10 0 0 0 1.60E+08 2.94E+08 - - - 4.0854 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19639.19639.2 0.00154 14-Jun R.GLDIYVWR.G sp|Q13045|FLII_HUMAN 1 1020.5393 1.56 51884 19639 2 1020.538688 511.2769 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3695.9 - 327097 - - - -0.5664 - 1.642 0.472 - 139.5 1 2 0 -0.0006 8 0 0 0 5.93E+06 3.80E+06 - - - 4.0227 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.19646.19646.2 0.000859 16-Aug K.GLFEVNPWK[136.11].R "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1096.5797 2.78 51889 19646 2 1096.582132 549.2971 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 6 3696.7 - 643220 - - - 2.2351 - 1.564 0.123 - 157.5 1 2 0 0.0025 9 0 0 0 3.80E+07 1.37E+07 - - - 1.2426 0.997 230117_WJC_METTL3_WT_vs_EV_F06.19648.19648.2 0.0487 12-Aug K.NFGIWLR.Y "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 904.4919 0.77 51891 19648 2 904.493983 453.2532 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 9.75 3696.9 - 236073 - - - 2.2786 - 1.414 0.192 - 326.1 1 2 0 0.0021 7 0 0 0 6.44E+07 8.38E+07 - - - 1.5561 0.8548 230117_WJC_METTL3_WT_vs_EV_F06.19649.19649.2 0.704 14-Jun R.LLFFAPTR[166.11].R sp|Q07820|MCL1_HUMAN 1 973.5625 4.78 51892 19649 2 973.568187 487.7885 Induced myeloid leukemia cell differentiation protein Mcl-1 OS=Homo sapiens OX=9606 GN=MCL1 PE=1 SV=3 9.75 3697.1 - 125064 - - - 5.8846 - 1.207 0.092 - 107 1 2 0 0.0057 8 0 0 0 1.08E+07 2.26E+06 - - - 0.2861 0.9933 230117_WJC_METTL3_WT_vs_EV_F06.19654.19654.2 0.379 12-Jun K.NFGIWLR[166.11].Y "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 914.5002 0.77 51895 19654 2 914.502951 458.2574 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 9.75 3697.7 - 1.77E+06 - - - 3.0169 - 1.387 0.155 - 208.5 1 2 0 0.0028 7 0 0 0 6.44E+07 8.38E+07 - - - 1.2215 0.9098 230117_WJC_METTL3_WT_vs_EV_F06.19666.19666.2 0.466 14-Sep L.IALALLAR.R sp|P43116|PE2R2_HUMAN 1 839.5593 999 51905 19666 2 839.560221 420.7869 Prostaglandin E2 receptor EP2 subtype OS=Homo sapiens OX=9606 GN=PTGER2 PE=1 SV=2 9.75 3699.2 - 668280 - - - 1.1292 - 1.887 0.164 - 362.8 1 1 0 0.0009 8 0 0 0 5.63E+06 0.00E+00 - - - 2.1671 0.982 230117_WJC_METTL3_WT_vs_EV_F06.19667.19667.2 0.00118 18-Dec R.TEVVSLLLDR.K "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1143.6499 1.49 51906 19667 2 1143.656171 572.8322 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 3699.3 - 586213 - - - 5.4492 - 2.061 0.094 - 489.5 1 2 0 0.0062 10 0 0 0 1.12E+07 7.55E+06 - - - 1.752 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.19668.19668.2 0.248 16-Sep K.GLFEVNPWK.R "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1088.5655 2.7 51907 19668 2 1088.567263 545.29 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 6 3699.4 - 1.09E+06 - - - 1.637 - 1.635 0.187 - 241.5 1 2 0 0.0018 9 0 0 0 4.32E+07 1.60E+07 - - - 1.844 0.9933 230117_WJC_METTL3_WT_vs_EV_F06.19669.19669.2 0.67 12-Jul K.LTFLDLR.N "sp|Q9H9A6|LRC40_HUMAN,tr|X6R5P2|X6R5P2_HUMAN" 2 876.5069 1.34 51908 19669 2 876.509993 439.2607 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.84 3699.5 - 687661 - - - 3.5254 - 1.568 0.137 - 224.7 1 2 0 0.0031 7 0 0 0 6.90E+06 5.15E+06 - - - 1.4771 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19672.19672.3 0.00066 Dec-40 R.MLIPYIEHWPR.A "sp|O75208|COQ9_HUMAN,tr|H3BPY0|H3BPY0_HUMAN,tr|H3BNT2|H3BNT2_HUMAN" 3 1453.754 4.4 51911 19672 3 1453.759205 485.592 "Ubiquinone biosynthesis protein COQ9, mitochondrial OS=Homo sapiens OX=9606 GN=COQ9 PE=1 SV=1" 6.5 3699.9 - 235870 - - - 3.5618 - 2.511 0.374 - 250.7 1 2 0 0.0052 11 0 0 0 3.61E+06 8.21E+05 - - - 5.3238 0.9952 230117_WJC_METTL3_WT_vs_EV_F06.19673.19673.2 0.014 14-Sep K.SVWALLQR[166.11].N sp|Q5VUD6|DIK1B_HUMAN 1 981.5635 2.18 51912 19673 2 981.567885 491.789 Divergent protein kinase domain 1B OS=Homo sapiens OX=9606 GN=DIPK1B PE=1 SV=3 9.47 3700 - 227647 - - - 4.447 - 1.678 0.24 - 247 1 2 0 0.0044 8 0 0 0 3.52E+06 1.62E+06 - - - 2.3733 0.9962 230117_WJC_METTL3_WT_vs_EV_F06.19674.19674.2 0.999 14-Jul K.SLLAGLLK[136.11].K "sp|P31751|AKT2_HUMAN,tr|M0R0P9|M0R0P9_HUMAN,tr|J3QKW1|J3QKW1_HUMAN,tr|J3QL45|J3QL45_HUMAN,tr|M0R283|M0R283_HUMAN,tr|M0QZW8|M0QZW8_HUMAN" 6 821.5466 0.61 51913 19674 2 821.549486 411.7806 RAC-beta serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=AKT2 PE=1 SV=2 8.47 3700.1 - 225069 - - - 3.5251 - 1.411 0.258 - 140.9 1 2 0 0.0029 8 0 0 0 8.46E+05 1.38E+06 - - - 1.9841 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.19675.19675.2 0.000221 16-Aug K.STLINTLFK[136.11].S "sp|Q9UHD8|SEPT9_HUMAN,tr|K7EKN4|K7EKN4_HUMAN,tr|K7EN52|K7EN52_HUMAN,tr|K7EQD7|K7EQD7_HUMAN,tr|K7ER52|K7ER52_HUMAN,tr|A0A6Q8PHC2|A0A6Q8PHC2_HUMAN,tr|K7ER14|K7ER14_HUMAN,tr|K7EIE4|K7EIE4_HUMAN,tr|K7EJZ2|K7EJZ2_HUMAN,tr|K7ENQ5|K7ENQ5_HUMAN,tr|K7EL40|K7EL40_HUMAN,tr|K7EK18|K7EK18_HUMAN" 12 1043.6106 1.24 51914 19675 2 1043.614745 522.8126 Septin-9 OS=Homo sapiens OX=9606 GN=SEPTIN9 PE=1 SV=2 8.47 3700.3 - 211678 - - - 3.9268 - 2.192 0.266 - 150.5 1 2 0 0.0041 9 0 0 0 2.51E+06 2.02E+06 - - - 3.2749 1 230117_WJC_METTL3_WT_vs_EV_F06.19676.19676.2 2.98E-05 26-Oct R.IMGIPEEEQMGLLR[166.11].V sp|P35579|MYH9_HUMAN 1 1624.8192 1.37 51915 19676 2 1624.830243 813.4169 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3700.4 - 191417 - - - 6.7848 - 1.923 0.568 - 231.7 1 2 0 0.011 14 0 0 0 7.57E+06 5.55E+06 - - - 4.8737 0.9969 230117_WJC_METTL3_WT_vs_EV_F06.19677.19677.2 0.155 24-Nov R.LENLGIPEEELLR.Q sp|Q01658|NC2B_HUMAN 1 1523.8195 4.18 51916 19677 2 1523.827401 762.917 Protein Dr1 OS=Homo sapiens OX=9606 GN=DR1 PE=1 SV=1 4.09 3700.5 - 131553 - - - 5.1699 - 2.449 0.301 - 325.4 1 2 0 0.0079 13 0 0 0 3.32E+06 7.94E+05 - - - 3.5605 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.19682.19682.2 0.0094 14-Sep R.NLFEQLVR.R "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VV47|F8VV47_HUMAN,tr|F8VUW9|F8VUW9_HUMAN,tr|F8VWY4|F8VWY4_HUMAN,tr|F8VRD2|F8VRD2_HUMAN,tr|F8VVY0|F8VVY0_HUMAN,tr|F8VZ66|F8VZ66_HUMAN,tr|F8VWX0|F8VWX0_HUMAN,tr|F8VS54|F8VS54_HUMAN,tr|F8W0L1|F8W0L1_HUMAN,tr|F8VVE5|F8VVE5_HUMAN,tr|F8VV39|F8VV39_HUMAN,tr|F8VXH1|F8VXH1_HUMAN" 13 1017.5607 1.41 51920 19682 2 1017.565315 509.7876 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 6 3701.2 - 310764 - - - 4.5059 - 1.646 0.27 - 338.8 1 2 0 0.0046 8 0 0 0 1.06E+07 7.50E+06 - - - 2.5368 1 230117_WJC_METTL3_WT_vs_EV_F06.19687.19687.3 1.16E-08 17/76 K.FEAHPNDLYVEGLPENIPFR.S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2356.1488 12.04 51925 19687 3 2356.160522 786.3902 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3701.8 - 41319.8 - - - 4.9763 - 3.184 0.579 - 240.3 1 2 0 0.0117 20 0 0 0 8.31E+06 6.91E+05 - - - 7.8017 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19690.19690.2 0.000538 18-Sep K.VAEITELILK[136.11].A "sp|Q06265|EXOS9_HUMAN,tr|D6R905|D6R905_HUMAN,tr|H0Y9L5|H0Y9L5_HUMAN,tr|D6RIY6|D6RIY6_HUMAN" 4 1135.6944 1.07 51926 19690 2 1135.695571 568.8545 Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3 4.53 3702.2 - 1.41E+06 - - - 1.0522 - 2.244 0.393 - 293.2 1 2 0 0.0012 10 0 0 0 1.46E+07 1.36E+07 - - - 4.1994 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.19692.19692.2 0.00129 18-Oct K.VAEITELILK.A "sp|Q06265|EXOS9_HUMAN,tr|D6R905|D6R905_HUMAN,tr|H0Y9L5|H0Y9L5_HUMAN,tr|D6RIY6|D6RIY6_HUMAN" 4 1127.6802 1.08 51928 19692 2 1127.686971 564.8474 Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3 4.53 3702.5 - 1.56E+06 - - - 6.0256 - 2.148 0.393 - 320.6 1 2 0 0.0068 10 0 0 0 1.46E+07 1.35E+07 - - - 4.0756 1 230117_WJC_METTL3_WT_vs_EV_F06.19693.19693.2 0.000295 20-Oct R.LFEAEAQDLFR.D sp|Q9H223|EHD4_HUMAN 1 1337.6616 2.33 51929 19693 2 1337.668609 669.8381 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3702.6 - 1.23E+06 - - - 5.2652 - 2.378 0.501 - 342.1 1 2 0 0.007 11 0 0 0 1.89E+07 8.08E+06 - - - 5.0826 1 230117_WJC_METTL3_WT_vs_EV_F06.19694.19694.2 2.48E-09 26-Dec R.IMGIPEEEQMGLLR.V sp|P35579|MYH9_HUMAN 1 1614.8109 1.37 51930 19694 2 1614.819683 808.4128 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3702.7 - 1.09E+06 - - - 5.4087 - 2.377 0.611 - 330.5 1 2 0 0.0087 14 0 0 0 7.57E+06 5.55E+06 - - - 5.7239 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19695.19695.3 5.09E-05 22/68 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 2.41 51931 19695 3 1918.075588 640.3618 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3702.9 - 1.04E+06 - - - 6.2448 - 3.227 0.477 - 525.9 1 2 0 0.012 18 0 0 0 1.89E+07 7.82E+06 - - - 6.772 1 230117_WJC_METTL3_WT_vs_EV_F06.19696.19696.2 6.31E-07 16/22 R.LPADTC[160.03]LLEFAR.L "sp|Q8NF37|PCAT1_HUMAN,tr|A0A0G2JQ62|A0A0G2JQ62_HUMAN,tr|A0A0G2JRI7|A0A0G2JRI7_HUMAN" 3 1404.7071 1.62 51932 19696 2 1404.71577 703.3608 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 4.37 3703 - 1.03E+06 - - - 6.1465 - 2.771 0.587 - 1099.2 1 2 0 0.0086 12 0 0 0 6.07E+06 3.74E+06 - - - 6.0556 1 230117_WJC_METTL3_WT_vs_EV_F06.19697.19697.2 0.00203 14/22 R.LPADTC[160.03]LLEFAR[166.11].L "sp|Q8NF37|PCAT1_HUMAN,tr|A0A0G2JQ62|A0A0G2JQ62_HUMAN,tr|A0A0G2JRI7|A0A0G2JRI7_HUMAN" 3 1414.7154 1.61 51933 19697 2 1414.722863 708.365 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 4.37 3703.1 - 807325 - - - 5.271 - 2.604 0.461 - 969.5 1 2 0 0.0075 12 0 0 0 6.04E+06 3.74E+06 - - - 4.9618 1 230117_WJC_METTL3_WT_vs_EV_F06.19698.19698.2 0.000278 20-Nov R.LFEAEAQDLFR[166.11].D sp|Q9H223|EHD4_HUMAN 1 1347.6698 2.33 51934 19698 2 1347.675865 674.8422 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3703.2 - 806969 - - - 4.4736 - 2.409 0.514 - 385.6 1 2 0 0.006 11 0 0 0 1.89E+07 8.08E+06 - - - 5.214 0.9949 230117_WJC_METTL3_WT_vs_EV_F06.19701.19701.3 0.00864 15/68 K.ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1928.0719 2.47 51937 19701 3 1928.081583 643.6979 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3703.6 - 602365 - - - 5.0325 - 2.065 0.273 - 82.2 1 2 0 0.0097 18 0 0 0 1.95E+07 7.88E+06 - - - 3.3866 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.19703.19703.2 0.00524 24-Nov K.ALLLVPASVNC[160.03]LR.L sp|Q5SRE5|NU188_HUMAN 1 1424.8174 2.07 51939 19703 2 1424.823332 713.416 Nucleoporin NUP188 OS=Homo sapiens OX=9606 GN=NUP188 PE=1 SV=1 8.29 3703.9 - 304423 - - - 4.1942 - 2.297 0.309 - 303.3 1 2 0 0.006 13 0 0 0 1.61E+06 7.77E+05 - - - 3.4557 0.9849 230117_WJC_METTL3_WT_vs_EV_F06.19704.19704.2 0.228 20-Jun K.YFNEFLDGELK.S "sp|O00471|EXOC5_HUMAN,tr|A0A0A0MSI8|A0A0A0MSI8_HUMAN" 2 1373.6503 1.78 51940 19704 2 1373.655152 687.8324 Exocyst complex component 5 OS=Homo sapiens OX=9606 GN=EXOC5 PE=1 SV=1 4.14 3704 - 274704 - - - 3.5082 - 1.106 0.206 - 81.6 1 2 0 0.0048 11 0 0 0 1.03E+06 5.77E+05 - - - 0.8336 1 230117_WJC_METTL3_WT_vs_EV_F06.19706.19706.2 4.72E-09 16/28 R.VMAGALEGDIFIGPK.A "sp|P61163|ACTZ_HUMAN,sp|P42025|ACTY_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 4 1516.796 1.26 51942 19706 2 1516.804052 759.4053 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4.37 3704.2 - 233864 - - - 5.3409 - 2.972 0.592 - 794.6 1 2 0 0.0081 15 0 0 0 9.49E+06 7.50E+06 - - - 6.0889 0.9887 230117_WJC_METTL3_WT_vs_EV_F06.19707.19707.2 0.00444 22-Sep R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 0.89 51943 19707 2 1323.809472 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3704.4 - 177765 - - - 6.7223 - 1.573 0.399 - 184 1 2 0 0.0089 12 0 0 0 1.15E+06 1.28E+06 - - - 3.1771 0.9915 230117_WJC_METTL3_WT_vs_EV_F06.19708.19708.2 0.528 14-Sep K.VAIIIPFR.N "sp|P15291|B4GT1_HUMAN,sp|O43286|B4GT5_HUMAN,tr|Q86XA6|Q86XA6_HUMAN" 3 927.5906 0.32 51944 19708 2 927.595431 464.8026 "Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5" 9.72 3704.5 - 172044 - - - 5.2372 - 1.958 0.172 - 291 1 2 0 0.0049 8 0 0 0 5.73E+06 1.78E+07 - - - 2.3364 0.9851 230117_WJC_METTL3_WT_vs_EV_F06.19709.19709.2 1.37 14-Jul K.VAIIIPFR[166.11].N "sp|P15291|B4GT1_HUMAN,sp|O43286|B4GT5_HUMAN,tr|Q86XA6|Q86XA6_HUMAN" 3 937.5988 0.2 51945 19709 2 937.60142 469.8067 "Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5" 9.72 3704.6 - 163715 - - - 2.7485 - 1.197 0.144 - 133.9 2 2 0 0.0026 8 0 0 0 5.73E+06 2.87E+07 - - - 0.5116 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.19717.19717.2 4.22 14-Jul K.LLILALER[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 949.62 1.37 51952 19717 2 949.621997 475.8173 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6 3705.4 - 2.98E+06 - - - 2.1314 - 1.541 0.133 - 166.4 1 2 0 0.002 8 0 0 0 2.75E+07 2.00E+07 - - - 1.3269 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19719.19719.2 9.21E-05 18-Oct R.C[160.03]LFQSPLFAK.A sp|Q86X55|CARM1_HUMAN 1 1209.6216 37.53 51954 19719 2 1209.624235 605.8181 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 8.22 3705.6 - 2.84E+06 - - - 2.1651 - 1.512 0.445 - 255.6 1 2 0 0.0026 10 0 0 0 8.24E+06 2.20E+05 - - - 3.481 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.19720.19720.2 0.0505 16-Aug R.VLLPVLLNK.N sp|O00186|STXB3_HUMAN 1 1007.6743 1.54 51955 19720 2 1007.676805 504.8444 Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2 8.72 3705.6 - 2.25E+06 - - - 2.4829 - 1.778 0.29 - 175.8 1 2 0 0.0025 9 0 0 0 4.76E+06 3.09E+06 - - - 2.8471 0.8638 230117_WJC_METTL3_WT_vs_EV_F06.19721.19721.2 0.0305 14-Jul F.GPILNFLR.H "sp|Q8N5Z5|KCD17_HUMAN,tr|H7C323|H7C323_HUMAN,tr|B0QYB2|B0QYB2_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 5 928.5494 0.62 51956 19721 2 928.551875 465.282 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 9.75 3705.7 - 2.08E+06 - - - 2.6256 - 1.666 0.204 - 198.8 1 1 0 0.0024 8 0 0 0 5.06E+06 8.12E+06 - - - 2.0864 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.19722.19722.2 0.0296 16-Sep K.LFSNVLILK.S "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1045.6536 1.43 51957 19722 2 1045.656161 523.8341 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.75 3705.8 - 1.99E+06 - - - 2.4798 - 1.344 0.363 - 180.3 1 2 0 0.0026 9 0 0 0 4.91E+06 3.43E+06 - - - 2.5766 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19723.19723.2 0.000427 16-Sep K.LFSNVLILK[136.11].S "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1053.6678 1.43 51958 19723 2 1053.670894 527.8412 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.75 3706 - 1.57E+06 - - - 2.9668 - 1.728 0.426 - 154.8 1 2 0 0.0031 9 0 0 0 4.91E+06 3.43E+06 - - - 3.7689 0.9462 230117_WJC_METTL3_WT_vs_EV_F06.19726.19726.2 2.6 24-Jun K.TISGPLIPPASPR.L "sp|A6NGB9|WIPF3_HUMAN,tr|A0A0A0MSG0|A0A0A0MSG0_HUMAN" 2 1304.7452 17.95 51961 19726 2 1304.74488 653.3799 WAS\WASL-interacting protein family member 3 OS=Homo sapiens OX=9606 GN=WIPF3 PE=1 SV=4 9.41 3706.3 - 1.14E+06 - - - -0.2729 - 1.316 0.069 - 38.6 18 2 0 -0.0004 13 0 0 0 2.50E+06 1.39E+05 - - - -0.3054 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.19727.19727.2 0.0124 16-Jul K.VIPTLALLK.D sp|O14530|TXND9_HUMAN 1 966.6478 2.27 51962 19727 2 966.649886 484.3312 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 8.72 3706.4 - 980732 - - - 2.2056 - 1.323 0.346 - 109.8 1 2 0 0.0021 9 0 0 0 9.09E+06 4.01E+06 - - - 2.4057 1 230117_WJC_METTL3_WT_vs_EV_F06.19728.19728.2 0.00019 18-Dec K.LLDEVFFSEK.L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1225.6231 1.65 51963 19728 2 1225.625317 613.8188 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3706.5 - 1.50E+06 - - - 1.8456 - 2.396 0.425 - 401 1 2 0 0.0023 10 0 0 0 2.19E+08 1.33E+08 - - - 4.6184 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19729.19729.2 2.69E-05 22-Nov K.ALSTFFVENSLR[166.11].T sp|Q9Y2V7|COG6_HUMAN 1 1392.7277 2.09 51964 19729 2 1392.729684 697.3711 Conserved oligomeric Golgi complex subunit 6 OS=Homo sapiens OX=9606 GN=COG6 PE=1 SV=2 6.05 3706.6 - 909678 - - - 1.4353 - 1.942 0.406 - 390.8 1 2 0 0.002 12 0 0 0 4.95E+06 2.37E+06 - - - 3.7854 1 230117_WJC_METTL3_WT_vs_EV_F06.19730.19730.2 0.137 24-Dec K.LLC[160.03]DSVVLQPYLR.E "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN,tr|H0YBB4|H0YBB4_HUMAN" 3 1574.8491 3.21 51965 19730 2 1574.848947 788.4318 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.83 3706.8 - 555847 - - - -0.0654 - 2.316 0.493 - 515.8 1 2 0 -0.0001 13 0 0 0 3.63E+06 1.13E+06 - - - 4.8377 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19735.19735.2 0.00359 14-Oct K.IPDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1069.5584 1.24 51969 19735 2 1069.561566 535.7865 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3707.2 - 1.91E+06 - - - 2.9274 - 1.783 0.377 - 396.9 1 2 0 0.0031 8 0 0 0 7.14E+09 5.77E+09 - - - 3.5687 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19736.19736.2 0.000425 18-Nov K.LLDEVFFSEK[136.11].L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1233.6373 1.65 51970 19736 2 1233.640162 617.8259 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3707.3 - 1.17E+06 - - - 2.3564 - 2.262 0.441 - 298.5 1 2 0 0.0029 10 0 0 0 2.19E+08 1.33E+08 - - - 4.5757 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.19738.19738.2 0.082 14-Jul K.DFLIPIGK[136.11].A "sp|P11177|ODPB_HUMAN,tr|F8WF02|F8WF02_HUMAN,tr|C9J634|C9J634_HUMAN" 3 909.5415 2 51972 19738 2 909.543247 455.778 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 5.84 3707.5 - 844789 - - - 1.9164 - 1.322 0.222 - 216.3 1 2 0 0.0017 8 0 0 0 8.77E+07 4.39E+07 - - - 1.522 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19744.19744.2 2.55E-05 24-Oct K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 0.29 51978 19744 2 1600.74806 801.3794 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3708.3 - 359500 - - - 2.3427 - 1.948 0.51 - 298.5 1 2 0 0.0038 13 0 0 0 7.42E+06 2.58E+07 - - - 4.5181 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.19747.19747.2 0.037 20-Aug K.TAAFALPVLER.L "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 1186.671 1.04 51981 19747 2 1186.675844 594.3428 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.66 3708.7 - 197769 - - - 4.0744 - 1.735 0.359 - 220 1 2 0 0.0048 11 0 0 0 9.04E+06 8.71E+06 - - - 3.1817 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.19748.19748.2 3.89E-06 13/22 R.IYGLGSLALYEK.A sp|P36542|ATPG_HUMAN 1 1325.7231 1.55 51982 19748 2 1325.729963 663.8688 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6 3708.8 - 174108 - - - 5.1738 - 2.596 0.382 - 423 1 2 0 0.0069 12 0 0 0 3.63E+08 2.35E+08 - - - 4.3704 1 230117_WJC_METTL3_WT_vs_EV_F06.19749.19749.2 6.07E-06 24-Oct K.IYVDDGLISLQVK[136.11].Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1469.8221 1.37 51983 19749 2 1469.825539 735.9183 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3709 - 150729 - - - 2.3425 - 2.081 0.541 - 253.1 1 2 0 0.0034 13 0 0 0 2.54E+06 1.85E+06 - - - 4.9166 1 230117_WJC_METTL3_WT_vs_EV_F06.19755.19755.2 2.67E-06 14/22 R.IYGLGSLALYEK[136.11].A sp|P36542|ATPG_HUMAN 1 1333.7373 1.55 51988 19755 2 1333.738288 667.8759 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6 3709.7 - 6.72E+06 - - - 0.7378 - 2.63 0.517 - 516.5 1 2 0 0.001 12 0 0 0 3.63E+08 2.35E+08 - - - 5.4036 0.9936 230117_WJC_METTL3_WT_vs_EV_F06.19756.19756.2 3.21 14-Jul K.DFLIPIGK.A "sp|P11177|ODPB_HUMAN,tr|F8WF02|F8WF02_HUMAN,tr|C9J634|C9J634_HUMAN" 3 901.5273 2.01 51989 19756 2 901.527402 451.7709 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 5.84 3709.8 - 4.58E+06 - - - 0.1087 - 1.472 0.112 - 201.9 1 2 0 0.0001 8 0 0 0 8.75E+07 4.36E+07 - - - 1.0342 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19758.19758.2 0.0321 16-Sep K.TLFPLIEAK[136.11].K sp|P13010|XRCC5_HUMAN 1 1038.6205 1 51991 19758 2 1038.622155 520.3175 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.66 3710 - 1.09E+06 - - - 1.6098 - 1.487 0.387 - 235.2 1 2 0 0.0017 9 0 0 0 4.29E+08 4.31E+08 - - - 3.0467 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19760.19760.2 0.00207 18-Sep K.SVLIGEFLEK.V "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1133.6332 0.92 51993 19760 2 1133.633088 567.8239 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 3710.1 - 960735 - - - -0.1217 - 1.823 0.385 - 262.2 1 2 0 -0.0001 10 0 0 0 1.35E+08 1.46E+08 - - - 3.5607 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19762.19762.2 1.79E-05 13/20 R.EVWALVQAGIR.D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1240.6928 1.12 51995 19762 2 1240.695302 621.3537 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.1 3710.4 - 897436 - - - 2.011 - 2.064 0.449 - 557.1 1 2 0 0.0025 11 0 0 0 9.23E+06 8.27E+06 - - - 4.3169 0.9943 230117_WJC_METTL3_WT_vs_EV_F06.19763.19763.2 0.415 14-Jul R.YILATLLK.E "sp|Q6PI48|SYDM_HUMAN,tr|A0A3B3IS01|A0A3B3IS01_HUMAN,tr|A0A3B3ISK7|A0A3B3ISK7_HUMAN,tr|A0A3B3IT01|A0A3B3IT01_HUMAN" 4 933.5899 1.14 51996 19763 2 933.590933 467.8022 "Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2 PE=1 SV=1" 8.59 3710.5 - 813184 - - - 1.1011 - 1.119 0.204 - 99.6 1 2 0 0.001 8 0 0 0 2.75E+06 2.42E+06 - - - 0.8865 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.19765.19765.3 0.0732 Nov-76 R.LALVTGGEIASTFDHPELVK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2096.1154 -1 51998 19765 3 2096.118712 699.7124 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 3710.8 - 662177 - - - 1.5939 - 1.954 0.188 - 121.1 1 2 0 0.0033 20 0 0 0 0.00E+00 0.00E+00 - - - 2.2602 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19771.19771.2 0.0075 16-Aug K.TLFPLIEAK.K sp|P13010|XRCC5_HUMAN 1 1030.6063 1 52002 19771 2 1030.60808 516.3104 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.66 3711.6 - 5.34E+06 - - - 1.7436 - 1.478 0.369 - 203.3 1 2 0 0.0018 9 0 0 0 4.29E+08 4.31E+08 - - - 2.8962 1 230117_WJC_METTL3_WT_vs_EV_F06.19772.19772.2 1.37E-06 15/22 K.ALEDAFLAIDAK.L sp|O15355|PPM1G_HUMAN 1 1275.6711 3.2 52003 19772 2 1275.672646 638.8428 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.03 3711.6 - 3.64E+06 - - - 1.237 - 2.731 0.579 - 686 1 2 0 0.0016 12 0 0 0 4.63E+07 1.45E+07 - - - 5.9605 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.19773.19773.2 0.000742 24-Oct R.GLLPGLLPAPADK[136.11].L sp|Q6P2E9|EDC4_HUMAN 1 1268.7584 1.93 52004 19773 2 1268.757832 635.3865 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 5.84 3711.8 - 707231 - - - -0.4272 - 1.997 0.174 - 299.9 1 2 0 -0.0005 13 0 0 0 9.03E+06 4.68E+06 - - - 2.1011 1 230117_WJC_METTL3_WT_vs_EV_F06.19774.19774.2 0.0229 13/22 R.TFLESPLDVGIK.L "sp|Q8TEU7|RPGF6_HUMAN,tr|B7Z7Y1|B7Z7Y1_HUMAN,tr|E9PCH4|E9PCH4_HUMAN,tr|D6RE77|D6RE77_HUMAN,tr|A0A5F9ZHG7|A0A5F9ZHG7_HUMAN" 5 1317.718 0.11 52005 19774 2 1317.722343 659.8663 Rap guanine nucleotide exchange factor 6 OS=Homo sapiens OX=9606 GN=RAPGEF6 PE=1 SV=2 4.37 3711.9 - 535918 - - - 3.2822 - 2.49 0.477 - 456.8 1 2 0 0.0043 12 0 0 0 3.71E+07 3.43E+08 - - - 4.9631 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19779.19779.2 0.000808 24-Oct R.GLLPGLLPAPADK.L sp|Q6P2E9|EDC4_HUMAN 1 1260.7442 1.93 52008 19779 2 1260.744513 631.3794 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 5.84 3712.4 - 331616 - - - 0.2689 - 2.091 0.379 - 272.9 1 2 0 0.0003 13 0 0 0 9.03E+06 4.68E+06 - - - 3.7334 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.19780.19780.2 0.00141 18-Sep R.GPILLPYQFR.M "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1202.6812 1.18 52009 19780 2 1202.685371 602.3479 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 8.75 3712.5 - 454836 - - - 3.4855 - 1.922 0.424 - 357.8 1 2 0 0.0042 10 0 0 0 2.52E+07 2.14E+07 - - - 3.9951 0.9867 230117_WJC_METTL3_WT_vs_EV_F06.19781.19781.2 0.0207 18-Oct R.GPILLPYQFR[166.11].M "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1212.6894 1.18 52010 19781 2 1212.698469 607.352 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 8.75 3712.6 - 639165 - - - 7.438 - 2.099 0.329 - 422.1 1 2 0 0.009 10 0 0 0 2.52E+07 2.14E+07 - - - 3.5378 0.91 230117_WJC_METTL3_WT_vs_EV_F06.19786.19786.2 0.341 12-Sep L.PDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 946.4661 1.22 52013 19786 2 946.465541 474.2403 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 6.27 3713.2 - 1.29E+06 - - - -0.5917 - 1.853 0.27 - 338.3 1 1 0 -0.0006 7 0 0 0 5.03E+07 4.12E+07 - - - 2.9894 1 230117_WJC_METTL3_WT_vs_EV_F06.19787.19787.3 2.05E-07 16/60 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 158.09 52014 19787 3 1787.0046 596.6753 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3713.3 - 1.79E+06 - - - 0.319 - 3.461 0.617 - 461.8 1 2 0 0.0006 16 0 0 0 2.02E+08 1.28E+06 - - - 8.6045 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19788.19788.2 0.00505 18-Aug K.ELLGQGLLLR[166.11].S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1120.6844 0.89 52015 19788 2 1120.686162 561.3495 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3713.3 - 4.68E+06 - - - 1.6044 - 1.89 0.343 - 241.9 1 2 0 0.0018 10 0 0 0 1.26E+08 1.41E+08 - - - 3.3507 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19792.19792.2 0.0144 18-Oct R.GPILLPYQFR[166.11].M "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1212.6894 1.18 52019 19792 2 1212.691626 607.352 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 8.75 3713.7 - 993021 - - - 1.7952 - 2.103 0.388 - 366.3 1 2 0 0.0022 10 0 0 0 2.52E+07 2.14E+07 - - - 3.981 0.9606 230117_WJC_METTL3_WT_vs_EV_F06.19793.19793.2 0.107 12-Aug L.PDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 956.4744 1.25 52020 19793 2 956.475033 479.2445 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 6.27 3713.8 - 923447 - - - 0.6921 - 1.763 0.335 - 264.5 1 1 0 0.0007 7 0 0 0 5.14E+07 4.13E+07 - - - 3.3117 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19794.19794.2 0.273 22-Nov K.LANILFTQELAR.R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1387.7823 1.4 52021 19794 2 1387.783519 694.8985 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3714 - 573006 - - - 0.8424 - 2.461 0.273 - 432.2 1 2 0 0.0012 12 0 0 0 2.64E+07 1.89E+07 - - - 3.4266 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.19796.19796.2 0.0359 20-Nov R.VLLQAFDVVER[166.11].S sp|Q15750|TAB1_HUMAN 1 1297.727 0.5 52023 19796 2 1297.724237 649.8708 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 OS=Homo sapiens OX=9606 GN=TAB1 PE=1 SV=1 4.37 3714.2 - 448924 - - - -2.096 - 2.103 0.302 - 371.5 2 2 0 -0.0027 11 0 0 0 1.45E+07 2.87E+07 - - - 3.1472 0.9877 230117_WJC_METTL3_WT_vs_EV_F06.19797.19797.2 1.24 14-Jul K.QFLLFTER.F sp|Q68CQ4|UTP25_HUMAN 1 1052.5655 999 52024 19797 2 1052.567005 527.29 U3 small nucleolar RNA-associated protein 25 homolog OS=Homo sapiens OX=9606 GN=UTP25 PE=1 SV=2 6 3714.3 - 353478 - - - 1.4479 - 1.237 0.088 - 115.4 1 2 0 0.0015 8 0 0 0 2.38E+06 0.00E+00 - - - 0.3319 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19798.19798.2 0.1 14-Jul R.MGLLAVLR.S "sp|O95394|AGM1_HUMAN,tr|D6RF77|D6RF77_HUMAN,tr|D6RC77|D6RC77_HUMAN,tr|D6RCQ8|D6RCQ8_HUMAN,tr|A0A494C099|A0A494C099_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C163|A0A494C163_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|D6RCD1|D6RCD1_HUMAN" 9 871.5313 2.36 52025 19798 2 871.532783 436.7729 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 9.5 3714.5 - 313217 - - - 1.6511 - 1.585 0.318 - 181.7 1 2 0 0.0014 8 0 0 0 5.96E+06 2.53E+06 - - - 2.7784 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19802.19802.2 0.0219 13/22 K.LANILFTQELAR[166.11].R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1397.7906 1.4 52027 19802 2 1397.791572 699.9026 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3715 - 0 - - - 0.6811 - 2.608 0.32 - 741.2 1 2 0 0.001 12 0 0 0 2.64E+07 1.89E+07 - - - 3.9264 1 230117_WJC_METTL3_WT_vs_EV_F06.19805.19805.2 1.73E-14 23/30 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 999 52030 19805 2 1787.011758 894.5093 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3715.4 - 0 - - - 4.3246 - 4.548 0.587 - 1615.5 1 2 0 0.0077 16 0 0 0 6.88E+07 0.00E+00 - - - 7.0981 0.9954 230117_WJC_METTL3_WT_vs_EV_F06.19806.19806.2 0.013 20-Nov K.ALLLSSVLSEK[136.11].G "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1166.7002 2.92 52031 19806 2 1166.706904 584.3574 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 6.05 3715.5 - 259080 - - - 5.7547 - 2.266 0.317 - 302.3 1 2 0 0.0067 11 0 0 0 1.03E+07 3.54E+06 - - - 3.5932 1 230117_WJC_METTL3_WT_vs_EV_F06.19810.19810.2 0.000246 20-Dec K.SFYGSTLFLC[160.03]R.R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1349.6438 1.46 52033 19810 2 1349.643722 675.8292 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 7.94 3716 - 1.17E+06 - - - -0.0637 - 2.405 0.511 - 483 1 2 0 -0.0001 11 0 0 0 1.38E+07 9.45E+06 - - - 5.1892 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19811.19811.2 0.00854 18-Sep K.ELLGQGLLLR.S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1110.6761 0.89 52034 19811 2 1110.676387 556.3453 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3716.1 - 1.47E+07 - - - 0.2638 - 1.901 0.322 - 325.3 1 2 0 0.0003 10 0 0 0 1.26E+08 1.41E+08 - - - 3.2123 1 230117_WJC_METTL3_WT_vs_EV_F06.19812.19812.2 6.25E-06 13/20 R.WGAFAQSILER[166.11].G sp|Q13472|TOP3A_HUMAN 1 1286.6647 0.63 52035 19812 2 1286.666315 644.3396 DNA topoisomerase 3-alpha OS=Homo sapiens OX=9606 GN=TOP3A PE=1 SV=1 6 3716.2 - 2.00E+06 - - - 1.2622 - 2.448 0.538 - 728 1 2 0 0.0016 11 0 0 0 6.39E+06 1.01E+07 - - - 5.4361 0.8749 230117_WJC_METTL3_WT_vs_EV_F06.19814.19814.3 0.0168 Dec-48 R.GAAGALLVYDITR.R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1318.7245 1.87 52037 19814 3 1318.728769 440.5821 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3716.5 - 538609 - - - 3.2365 - 1.767 0.019 - 196.2 1 2 0 0.0043 13 0 0 0 5.58E+06 2.98E+06 - - - 0.2941 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.19823.19823.2 2.20E-06 20-Oct R.VLLQAFDVVER.S sp|Q15750|TAB1_HUMAN 1 1287.7187 0.5 52042 19823 2 1287.717693 644.8666 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 OS=Homo sapiens OX=9606 GN=TAB1 PE=1 SV=1 4.37 3717.5 - 659450 - - - -0.7719 - 2.268 0.328 - 424.9 1 2 0 -0.001 11 0 0 0 1.45E+07 2.87E+07 - - - 3.6786 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.19824.19824.2 0.00273 18-Sep K.QLEDILVLAK[136.11].Q "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A0A6YYJ5|A0A0A6YYJ5_HUMAN" 8 1148.6896 4.53 52043 19824 2 1148.688255 575.3521 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.37 3717.5 - 0 - - - -1.1927 - 1.684 0.435 - 161.8 1 2 0 -0.0014 10 0 0 0 1.94E+07 4.29E+06 - - - 3.7082 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19828.19828.2 4.21E-07 15/24 R.GAAGALLVYDITR[166.11].R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1328.7328 0.86 52045 19828 2 1328.73366 665.3737 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3718 - 6.48E+06 - - - 0.6691 - 3.251 0.126 - 1092.8 1 2 0 0.0009 13 0 0 0 5.84E+07 6.82E+07 - - - 2.9972 1 230117_WJC_METTL3_WT_vs_EV_F06.19829.19829.2 4.18E-05 15/22 K.PYRPWGTEIGAF.- "sp|Q9Y5J3|HEY1_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 4 1392.6826 2.51 52046 19829 2 1392.679729 697.3486 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 6.43 3718.1 - 1.77E+06 - - - -2.0873 - 2.241 0.508 - 713.5 1 1 0 -0.0029 12 0 0 0 1.13E+07 4.50E+06 - - - 4.9153 0.9833 230117_WJC_METTL3_WT_vs_EV_F06.19830.19830.2 0.881 12-Jun R.VLIWDIR.E "sp|Q96JK2|DCAF5_HUMAN,tr|G3V3S1|G3V3S1_HUMAN,tr|Q8TBB7|Q8TBB7_HUMAN" 3 913.5385 2.68 52047 19830 2 913.536349 457.7765 DDB1- and CUL4-associated factor 5 OS=Homo sapiens OX=9606 GN=DCAF5 PE=1 SV=2 5.81 3718.2 - 1.66E+06 - - - -2.3962 - 1.396 0.191 - 117.4 1 2 0 -0.0022 7 0 0 0 4.43E+06 1.66E+06 - - - 1.5081 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19832.19832.2 3.31E-05 22-Nov K.YLGPAVLMQAYR.W sp|P21912|SDHB_HUMAN 1 1380.7224 4.94 52049 19832 2 1380.723201 691.3685 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 8.59 3718.5 - 1.49E+06 - - - 0.5859 - 2.019 0.42 - 386.2 1 2 0 0.0008 12 0 0 0 1.07E+07 2.16E+06 - - - 3.9915 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19833.19833.2 0.002 18-Sep K.GIYLWDVEGR[166.11].K sp|P04181|OAT_HUMAN 1 1216.6116 1.14 52050 19833 2 1216.610915 609.3131 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.37 3718.6 - 1.39E+06 - - - -0.5573 - 1.82 0.424 - 246.2 1 2 0 -0.0007 10 0 0 0 7.00E+06 6.16E+06 - - - 3.844 0.9965 230117_WJC_METTL3_WT_vs_EV_F06.19842.19842.2 0.288 14-Jul R.SLPVFPFR.E "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 961.5385 1.49 52057 19842 2 961.539447 481.7765 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 9.47 3719.6 - 237486 - - - 0.9454 - 1.305 0.193 - 155.5 1 2 0 0.0009 8 0 0 0 6.16E+06 4.14E+06 - - - 1.2691 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19843.19843.2 0.00513 16-Aug R.ILDTLGLLR[166.11].Q "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN,tr|A0A087WWF4|A0A087WWF4_HUMAN" 3 1022.6364 1.14 52058 19843 2 1022.63796 512.3255 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 5.84 3719.7 - 0 - - - 1.5734 - 1.734 0.324 - 162.7 1 2 0 0.0016 9 0 0 0 1.59E+07 1.40E+07 - - - 3.026 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.19844.19844.2 0.0121 18-Aug K.QLEDILVLAK.Q "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A0A6YYJ5|A0A0A6YYJ5_HUMAN" 8 1140.6754 4.76 52059 19844 2 1140.674882 571.345 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.37 3719.7 - 198369 - - - -0.476 - 1.562 0.344 - 162.6 1 2 0 -0.0005 10 0 0 0 2.10E+07 4.40E+06 - - - 2.8264 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19845.19845.2 0.0018 24-Dec R.LVDIIAAVPPQYR.K "sp|Q9H9T3|ELP3_HUMAN,tr|E5RIZ7|E5RIZ7_HUMAN,tr|E5RIC0|E5RIC0_HUMAN,tr|E5RHY2|E5RHY2_HUMAN,tr|E5RHR2|E5RHR2_HUMAN" 5 1453.8293 1.8 52060 19845 2 1453.829397 727.9219 Elongator complex protein 3 OS=Homo sapiens OX=9606 GN=ELP3 PE=1 SV=2 5.84 3719.9 - 0 - - - 0.0667 - 2.545 0.4 - 460.7 1 2 0 0.0001 13 0 0 0 3.85E+06 2.14E+06 - - - 4.3928 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.19848.19848.2 0.00025 18-Jul R.NVEELVIVLK[136.11].K "sp|P53618|COPB_HUMAN,tr|E9PP73|E9PP73_HUMAN" 2 1162.7053 2.44 52063 19848 2 1162.707182 582.3599 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 4.53 3720.2 - 0 - - - 1.6401 - 1.701 0.217 - 109 1 2 0 0.0019 10 0 0 0 6.41E+06 2.63E+06 - - - 2.1259 0.9795 230117_WJC_METTL3_WT_vs_EV_F06.19849.19849.3 0.266 Aug-32 K.EFIHILYFR.H "sp|Q9NZ32|ARP10_HUMAN,tr|G3V2Q5|G3V2Q5_HUMAN,tr|G3V5Y4|G3V5Y4_HUMAN,tr|F6S9Y6|F6S9Y6_HUMAN,tr|V9GYX7|V9GYX7_HUMAN" 5 1236.6655 1.5 52064 19849 3 1236.665525 413.2291 Actin-related protein 10 OS=Homo sapiens OX=9606 GN=ACTR10 PE=1 SV=1 6.85 3720.4 - 0 - - - -0.0032 - 1.378 0.156 - 81.7 1 2 0 0 9 0 0 0 2.31E+06 1.55E+06 - - - 1.2456 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.19852.19852.2 0.0153 14-Aug R.NLIEWLNK[136.11].Y sp|Q96DG6|CMBL_HUMAN 1 1036.5797 0.83 52065 19852 2 1036.581 519.2971 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 6 3720.8 - 3.10E+07 - - - 1.2725 - 1.685 0.258 - 225.1 1 2 0 0.0013 8 0 0 0 9.07E+07 1.10E+08 - - - 2.5198 1 230117_WJC_METTL3_WT_vs_EV_F06.19853.19853.2 0.000411 14/20 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 13.89 52066 19853 2 1276.702252 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3720.8 - 1.40E+07 - - - -0.3533 - 2.745 0.396 - 967.1 1 2 0 -0.0005 11 0 0 0 1.29E+08 9.29E+06 - - - 4.6974 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19854.19854.2 0.0366 16-Nov R.ILDTLGLLR.Q "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN,tr|A0A087WWF4|A0A087WWF4_HUMAN" 3 1012.6281 1.11 52067 19854 2 1012.629902 507.3213 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 5.84 3720.9 - 7.91E+06 - - - 1.7983 - 2.381 0.404 - 327.7 1 2 0 0.0018 9 0 0 0 1.56E+07 1.40E+07 - - - 4.5342 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19858.19858.2 0.000352 18-Oct K.GIYLWDVEGR.K sp|P04181|OAT_HUMAN 1 1206.6033 1.17 52071 19858 2 1206.605377 604.3089 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.37 3721.4 - 1.51E+06 - - - 1.7023 - 1.906 0.467 - 342 1 2 0 0.0021 10 0 0 0 7.00E+06 5.98E+06 - - - 4.29 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19860.19860.2 0.0406 24-Dec K.LDNLLLDTEGYVK.L "sp|Q16512|PKN1_HUMAN,tr|K7EL10|K7EL10_HUMAN" 2 1491.7821 -1 52073 19860 2 1491.782836 746.8983 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 4.03 3721.7 - 1.08E+06 - - - 0.5101 - 2.494 0.365 - 463.1 1 2 0 0.0008 13 0 0 0 0.00E+00 0.00E+00 - - - 4.0822 1 230117_WJC_METTL3_WT_vs_EV_F06.19863.19863.2 4.67E-08 13/26 K.FYGPAGPYGIFAGR[166.11].D sp|O15173|PGRC2_HUMAN 1 1481.7331 1.57 52076 19863 2 1481.73407 741.8738 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3722.1 - 777270 - - - 0.6513 - 2.233 0.57 - 505 1 2 0 0.001 14 0 0 0 2.33E+07 1.49E+07 - - - 5.2667 1 230117_WJC_METTL3_WT_vs_EV_F06.19865.19865.2 1.56E-05 18-Dec R.LNDYIFSFDK.M sp|P54136|SYRC_HUMAN 1 1260.6027 1.28 52078 19865 2 1260.599664 631.3086 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.21 3722.3 - 757296 - - - -2.3719 - 2.621 0.533 - 842.3 1 2 0 -0.003 10 0 0 0 3.19E+06 2.50E+06 - - - 5.6664 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19873.19873.2 3.59E-08 13/24 R.AGLNGLQLAVLAR.L sp|Q96S55|WRIP1_HUMAN 1 1294.7721 5.36 52085 19873 2 1294.773428 648.3933 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 9.79 3723.4 - 853182 - - - 1.0102 - 2.596 0.231 - 699.9 1 2 0 0.0013 13 0 0 0 5.32E+06 9.91E+05 - - - 3.1952 1 230117_WJC_METTL3_WT_vs_EV_F06.19874.19874.2 5.35E-06 20-Oct K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 8.7 52086 19874 2 1184.716087 593.3637 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3723.4 - 2.13E+07 - - - 2.7129 - 2.144 0.519 - 379.2 1 2 0 0.0032 11 0 0 0 1.68E+09 1.93E+08 - - - 4.9365 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19875.19875.2 0.00845 18-Oct R.AAFVLPEFAR.K "sp|P19623|SPEE_HUMAN,tr|K7EL89|K7EL89_HUMAN" 2 1119.6077 5.74 52087 19875 2 1119.606922 560.8111 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 6.05 3723.4 - 6.24E+06 - - - -0.677 - 2.006 0.419 - 262.4 1 2 0 -0.0008 10 0 0 0 6.11E+07 1.06E+07 - - - 4.0786 0.9918 230117_WJC_METTL3_WT_vs_EV_F06.19877.19877.2 0.121 12-Jun R.WLSQYID.- "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 923.4389 - 52089 19877 2 923.438871 462.7267 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.3 3723.6 - 3.96E+06 - - - -0.013 - 1.082 0.218 - 86.8 1 2 0 0 7 0 0 0 - - - - - 0.9009 0.9859 230117_WJC_METTL3_WT_vs_EV_F06.19878.19878.2 0.484 12-Jun K.LLDDLFR[166.11].K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 900.4944 1.06 52090 19878 2 900.494421 451.2545 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3723.6 - 3.10E+06 - - - -0.0189 - 1.271 0.096 - 103.3 1 2 0 0 7 0 0 0 1.59E+08 1.51E+08 - - - 0.5099 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.19879.19879.2 0.517 18-Sep K.IINFAPSLLR[166.11].L "sp|O15397|IPO8_HUMAN,tr|F5H2I3|F5H2I3_HUMAN" 2 1152.6894 1.21 52091 19879 2 1152.690572 577.352 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 9.75 3723.6 - 2.96E+06 - - - 0.9742 - 1.805 0.319 - 232.2 1 2 0 0.0011 10 0 0 0 1.78E+07 1.47E+07 - - - 3.0452 1 230117_WJC_METTL3_WT_vs_EV_F06.19880.19880.2 3.95E-11 17/26 K.FYGPAGPYGIFAGR.D sp|O15173|PGRC2_HUMAN 1 1471.7248 1.57 52092 19880 2 1471.725513 736.8697 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3723.7 - 2.93E+06 - - - 0.4607 - 2.817 0.583 - 1082.3 1 2 0 0.0007 14 0 0 0 2.33E+07 1.49E+07 - - - 5.9458 1 230117_WJC_METTL3_WT_vs_EV_F06.19881.19881.2 1.68E-07 13/20 K.TAVETAVLLLR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1194.7211 8.7 52093 19881 2 1194.722592 598.3678 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3723.8 - 2.91E+06 - - - 1.2128 - 2.696 0.589 - 744.4 1 2 0 0.0014 11 0 0 0 1.68E+09 1.93E+08 - - - 6.0739 0.9968 230117_WJC_METTL3_WT_vs_EV_F06.19882.19882.2 0.717 12-Jul K.LLDDLFR.K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 890.4862 1.06 52094 19882 2 890.48639 446.2504 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3723.8 - 2.46E+06 - - - 0.2493 - 1.503 0.165 - 176 1 2 0 0.0002 7 0 0 0 1.59E+08 1.51E+08 - - - 1.5507 1 230117_WJC_METTL3_WT_vs_EV_F06.19884.19884.2 6.04E-05 16-Oct K.YDWDLLAAR[166.11].S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1131.5588 1.74 52096 19884 2 1131.559462 566.7867 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3723.9 - 1.59E+06 - - - 0.5594 - 2.036 0.498 - 395.7 1 2 0 0.0006 9 0 0 0 7.92E+07 4.55E+07 - - - 4.776 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19885.19885.2 0.274 20-Oct -.MLLFVEQVASK.G "sp|Q71RC2|LARP4_HUMAN,tr|F8W1Z5|F8W1Z5_HUMAN" 2 1263.6897 0.28 52097 19885 2 1263.691661 632.8521 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 5.75 3724 - 1.52E+06 - - - 1.5558 - 2.112 0.358 - 298 1 2 0 0.002 11 0 0 0 9.98E+06 3.57E+07 - - - 3.7071 1 230117_WJC_METTL3_WT_vs_EV_F06.19890.19890.2 3.67E-06 13/22 K.IYDALDVSLIER.G sp|P54136|SYRC_HUMAN 1 1405.7453 1.54 52102 19890 2 1405.747237 703.8799 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.03 3724.4 - 1.07E+06 - - - 1.3808 - 2.692 0.577 - 670.6 1 2 0 0.0019 12 0 0 0 1.13E+07 7.35E+06 - - - 5.9077 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19894.19894.2 0.00124 14-Aug K.IPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1059.5502 -1 52105 19894 2 1059.551196 530.7824 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3724.8 - 3.18E+07 - - - 0.9731 - 1.596 0.513 - 407.9 1 2 0 0.001 8 0 0 0 0.00E+00 0.00E+00 - - - 4.2397 0.8547 230117_WJC_METTL3_WT_vs_EV_F06.19896.19896.2 1.04 20-May K.FNIFYPDLIDK.R "sp|Q8WUQ7|CATIN_HUMAN,tr|K7EIU6|K7EIU6_HUMAN,tr|K7ENY9|K7ENY9_HUMAN" 3 1383.7075 -1 52107 19896 2 1383.718877 692.861 Cactin OS=Homo sapiens OX=9606 GN=CACTIN PE=1 SV=3 4.21 3724.9 - 2.71E+06 - - - 8.2554 - 1.81 0.156 - 74.9 19 2 0 0.0114 11 0 0 0 0.00E+00 0.00E+00 - - - 1.2235 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.19897.19897.2 0.00114 14-Aug R.DWVLNEFK.H "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1049.5182 0.93 52108 19897 2 1049.518927 525.7664 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3725 - 2.39E+06 - - - 0.6965 - 1.534 0.326 - 254.3 1 2 0 0.0007 8 0 0 0 1.01E+08 1.08E+08 - - - 2.7391 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.19899.19899.2 6.43E-05 18-Nov R.QEVVDLLLAR.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1154.6659 1.32 52110 19899 2 1154.66316 578.3402 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3725.2 - 1.32E+06 - - - -2.3929 - 2.365 0.404 - 511.6 1 2 0 -0.0028 10 0 0 0 7.11E+07 5.40E+07 - - - 4.4268 1 230117_WJC_METTL3_WT_vs_EV_F06.19900.19900.2 1.03E-05 18-Dec R.QEVVDLLLAR[166.11].G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1164.6742 1.32 52111 19900 2 1164.674755 583.3444 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3725.3 - 1.14E+06 - - - 0.4825 - 2.487 0.536 - 863.3 1 2 0 0.0006 10 0 0 0 7.11E+07 5.40E+07 - - - 5.5428 1 230117_WJC_METTL3_WT_vs_EV_F06.19901.19901.2 3.32E-05 14/20 K.FDGILGMAYPR.L "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1238.6118 9.05 52112 19901 2 1238.608485 620.3132 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.84 3725.4 - 630190 - - - -2.6594 - 2.353 0.466 - 752.5 1 2 0 -0.0033 11 0 0 0 2.22E+07 2.45E+06 - - - 4.7967 0.9059 230117_WJC_METTL3_WT_vs_EV_F06.19903.19903.2 0.000366 22-Nov K.LLQVASPFLEPH.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1349.7343 - 52114 19903 2 1349.739764 675.8744 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 5.24 3725.7 - 424182 - - - 4.0208 - 1.99 0.388 - 164.6 1 1 0 0.0054 12 0 0 0 - - - - - 3.7157 1 230117_WJC_METTL3_WT_vs_EV_F06.19904.19904.2 0.000109 14/24 R.AIVFVVDSAAFQR.E "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1421.7667 3.71 52115 19904 2 1421.765779 711.8906 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.88 3725.8 - 355582 - - - -0.6478 - 2.932 0.514 - 788.6 1 2 0 -0.0009 13 0 0 0 5.42E+06 1.46E+06 - - - 5.5979 1 230117_WJC_METTL3_WT_vs_EV_F06.19912.19912.2 8.79E-05 16-Sep K.YDWDLLAAR.S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1121.5506 1.73 52121 19912 2 1121.552736 561.7826 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3726.8 - 6.55E+06 - - - 1.9411 - 1.935 0.564 - 337.4 1 2 0 0.0022 9 0 0 0 7.97E+07 4.62E+07 - - - 5.1157 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.19913.19913.3 0.00289 14/40 K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 6.68 52122 19913 3 1184.714163 395.9116 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3726.9 - 1.68E+06 - - - 1.0889 - 2.419 0.403 - 315.1 1 2 0 0.0013 11 0 0 0 3.01E+07 4.50E+06 - - - 5.5422 1 230117_WJC_METTL3_WT_vs_EV_F06.19921.19921.2 8.72E-06 24-Dec R.VETPVLPPVLVPR.H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1414.8548 2.26 52130 19921 2 1414.853773 708.4347 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3727.6 - 363278 - - - -0.7167 - 2.452 0.53 - 327.8 1 2 0 -0.001 13 0 0 0 1.54E+07 6.80E+06 - - - 5.2572 0.999 230117_WJC_METTL3_WT_vs_EV_F06.19924.19924.2 0.00405 16-Oct R.LVLDPYLLK.Y "sp|Q9Y2R5|RT17_HUMAN,tr|I3L0E3|I3L0E3_HUMAN,tr|E9PE17|E9PE17_HUMAN" 3 1072.6532 0.9 52131 19924 2 1072.656531 537.3339 "28S ribosomal protein S17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS17 PE=1 SV=1" 5.83 3728.1 - 4.62E+06 - - - 3.0746 - 1.563 0.391 - 232.5 1 2 0 0.0033 9 0 0 0 3.10E+07 3.43E+07 - - - 3.2199 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.19925.19925.2 0.266 14-Oct R.SLLSILQR.S "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 928.5706 2.29 52132 19925 2 928.570607 465.2926 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 9.47 3728.2 - 2.49E+06 - - - 0.0442 - 1.709 0.182 - 420.5 1 2 0 0 8 0 0 0 1.93E+07 8.45E+06 - - - 2.0015 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19928.19928.2 9.42E-06 18-Sep R.LWGDIYFNPK.T sp|Q15029|U5S1_HUMAN 1 1251.6288 1.11 52135 19928 2 1251.628913 626.8217 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.83 3728.5 - 1.19E+06 - - - 0.0831 - 1.744 0.502 - 254.4 1 2 0 0.0001 10 0 0 0 1.06E+07 9.52E+06 - - - 4.3012 0.9783 230117_WJC_METTL3_WT_vs_EV_F06.19929.19929.2 0.833 12-Jul K.DIILPFR.V "sp|Q96CW1|AP2M1_HUMAN,tr|A0A087WY71|A0A087WY71_HUMAN,tr|C9JJ47|C9JJ47_HUMAN,tr|E9PFW3|E9PFW3_HUMAN" 4 872.512 1.76 52136 19929 2 872.513749 437.2633 AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2 5.84 3728.6 - 1.18E+06 - - - 2.0172 - 1.363 0 - 185.9 1 2 0 0.0018 7 0 0 0 1.66E+07 9.40E+06 - - - 0.0217 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.19931.19931.2 0.000331 16-Nov K.SLTYLSILR[166.11].N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 3 1074.6313 1.29 52138 19931 2 1074.629654 538.3229 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 8.46 3728.8 - 4.62E+06 - - - -1.5 - 1.67 0.384 - 293 1 2 0 -0.0016 9 0 0 0 2.37E+07 1.84E+07 - - - 3.3603 0.999 230117_WJC_METTL3_WT_vs_EV_F06.19933.19933.2 0.000374 20-Nov R.IAIQGIITAIK.Y sp|Q6NSI4|RADX_HUMAN 1 1139.7278 2.8 52140 19933 2 1139.726202 570.8712 RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2 8.75 3729.1 - 727898 - - - -1.3977 - 2.235 0.405 - 212.3 1 2 0 -0.0016 11 0 0 0 6.40E+06 2.29E+06 - - - 4.2075 0.9381 230117_WJC_METTL3_WT_vs_EV_F06.19934.19934.2 5.73 12-Jul K.DIILPFR[166.11].V "sp|Q96CW1|AP2M1_HUMAN,tr|A0A087WY71|A0A087WY71_HUMAN,tr|C9JJ47|C9JJ47_HUMAN,tr|E9PFW3|E9PFW3_HUMAN" 4 882.5203 1.76 52141 19934 2 882.519846 442.2674 AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2 5.84 3729.2 - 677426 - - - -0.468 - 1.222 0 - 229.9 1 2 0 -0.0004 7 0 0 0 1.66E+07 9.40E+06 - - - -0.3239 0.997 230117_WJC_METTL3_WT_vs_EV_F06.19936.19936.2 2.69 12-Aug R.VTLLLFK.D "sp|Q9Y3C4|TPRKB_HUMAN,sp|Q86YN1|DOPP1_HUMAN,tr|H7C1Z8|H7C1Z8_HUMAN,tr|H7BXT6|H7BXT6_HUMAN" 4 832.5422 1.33 52143 19936 2 832.542668 417.2784 EKC\KEOPS complex subunit TPRKB OS=Homo sapiens OX=9606 GN=TPRKB PE=1 SV=1 8.72 3729.5 - 601076 - - - 0.5309 - 1.599 0.13 - 267.2 1 2 0 0.0004 7 0 0 0 3.63E+06 2.73E+06 - - - 1.4883 0.9823 230117_WJC_METTL3_WT_vs_EV_F06.19939.19939.2 0.0198 20-Sep R.VALDSLVLQMK.S sp|Q14147|DHX34_HUMAN 1 1215.6897 3.23 52146 19939 2 1215.699045 608.8521 Probable ATP-dependent RNA helicase DHX34 OS=Homo sapiens OX=9606 GN=DHX34 PE=1 SV=2 5.81 3729.9 - 459370 - - - 7.6911 - 1.759 0.367 - 183.3 1 2 0 0.0093 11 0 0 0 2.51E+06 7.77E+05 - - - 3.2765 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.19941.19941.2 0.00128 16-Sep R.GFFGFPGPR.S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 980.4868 1.88 52148 19941 2 980.485779 491.2507 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3730.1 - 426917 - - - -1.0791 - 1.785 0.44 - 249 1 2 0 -0.0011 9 0 0 0 3.43E+07 1.82E+07 - - - 3.9668 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.19945.19945.2 0.0101 12-May K.NMFAIWR.V "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 936.464 0.98 52151 19945 2 936.464595 469.2393 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3730.6 - 5.03E+06 - - - 0.6428 - 1.114 0.392 - 126.6 1 2 0 0.0006 7 0 0 0 4.37E+07 4.47E+07 - - - 2.2782 0.9926 230117_WJC_METTL3_WT_vs_EV_F06.19946.19946.2 0.00967 18-Sep K.GIGFLTSGWR.F sp|Q8IXM3|RM41_HUMAN 1 1092.5716 1.08 52152 19946 2 1092.578875 547.2931 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 9.75 3730.7 - 4.67E+06 - - - 6.6321 - 1.874 0.404 - 246 1 2 0 0.0072 10 0 0 0 3.93E+07 3.65E+07 - - - 3.7758 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.19948.19948.2 0.697 16-Aug R.NLLGLALGR.L sp|Q8N5L8|RP25L_HUMAN 1 925.5709 1.07 52154 19948 2 925.571933 463.7927 Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1 9.75 3730.7 - 4.42E+06 - - - 1.115 - 1.769 0.115 - 234.7 1 2 0 0.001 9 0 0 0 6.45E+07 6.03E+07 - - - 1.5403 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.19949.19949.2 0.0061 16-Aug K.SLTYLSILR.N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 3 1064.623 1.32 52155 19949 2 1064.62455 533.3188 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 8.46 3730.8 - 2.64E+06 - - - 1.4597 - 1.755 0.43 - 224.9 1 2 0 0.0016 9 0 0 0 2.37E+07 1.80E+07 - - - 3.8437 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.19950.19950.2 0.000553 18-Jul R.LLVVYPWTQR.F "sp|P69892|HBG2_HUMAN,sp|P69891|HBG1_HUMAN,sp|P02042|HBD_HUMAN,sp|P02100|HBE_HUMAN,sp|P68871|HBB_HUMAN,tr|A0A2R8Y7R2|A0A2R8Y7R2_HUMAN,tr|E9PEW8|E9PEW8_HUMAN,tr|E9PFT6|E9PFT6_HUMAN,tr|F8W6P5|F8W6P5_HUMAN,tr|A0A2R8Y7X9|A0A2R8Y7X9_HUMAN" 10 1273.7183 999 52156 19950 2 1273.719675 637.8664 Hemoglobin subunit gamma-2 OS=Homo sapiens OX=9606 GN=HBG2 PE=1 SV=2 8.75 3730.8 - 1.44E+06 - - - 1.085 - 1.748 0.259 - 205.2 1 2 0 0.0014 10 0 0 0 4.44E+07 0.00E+00 - - - 2.5124 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.19951.19951.2 0.00315 20-Jul R.VFSWGFGGYGR.L sp|Q9P258|RCC2_HUMAN 1 1231.5774 1.92 52157 19951 2 1231.578885 616.796 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 8.72 3730.9 - 949336 - - - 1.1709 - 1.436 0.383 - 141 1 2 0 0.0014 11 0 0 0 9.23E+06 4.82E+06 - - - 2.8483 1 230117_WJC_METTL3_WT_vs_EV_F06.19952.19952.2 7.11E-08 14/22 K.LYDNLLEQNLIR[166.11].V sp|O00231|PSD11_HUMAN 1 1512.8176 1.75 52158 19952 2 1512.818434 757.4161 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3731 - 936752 - - - 0.5757 - 3.039 0.559 - 763.2 1 2 0 0.0009 12 0 0 0 3.95E+07 2.27E+07 - - - 6.0941 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19953.19953.2 8.01E-06 24-Dec R.VETPVLPPVLVPR[166.11].H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1424.8631 2.25 52159 19953 2 1424.867416 713.4388 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3731.1 - 554178 - - - 3.0592 - 2.053 0.496 - 337 1 2 0 0.0044 13 0 0 0 1.53E+07 6.80E+06 - - - 4.5492 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19954.19954.2 0.000159 16-Sep R.GFFGFPGPR[166.11].S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 990.4951 1.96 52160 19954 2 990.496324 496.2548 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3731.2 - 472212 - - - 1.2287 - 1.582 0.442 - 224.6 1 2 0 0.0012 9 0 0 0 3.32E+07 1.69E+07 - - - 3.6322 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.19955.19955.2 9.58E-05 28-Aug R.LTPSASLPPAQLLLR.A "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 1575.9348 2.38 52161 19955 2 1575.934835 788.9747 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 9.75 3731.3 - 289880 - - - 0.0044 - 1.815 0.469 - 111.4 1 2 0 0 15 0 0 0 2.31E+06 9.72E+05 - - - 3.9705 1 230117_WJC_METTL3_WT_vs_EV_F06.19960.19960.2 0.00587 20-Dec R.TLVLLDNLNVR[166.11].E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1278.7535 1.26 52164 19960 2 1278.756471 640.384 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3731.9 - 5.26E+06 - - - 2.3187 - 2.708 0.506 - 576.5 1 2 0 0.003 11 0 0 0 3.60E+07 2.86E+07 - - - 5.4724 1 230117_WJC_METTL3_WT_vs_EV_F06.19961.19961.3 3.11E-07 19/76 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 2.87 52165 19961 3 2197.091722 733.3694 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3731.9 - 4.12E+06 - - - 2.4878 - 4.194 0.618 - 426.6 1 2 0 0.0055 20 0 0 0 9.52E+06 3.31E+06 - - - 8.9067 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.19965.19965.2 0.192 16-Sep R.GSLITSLLR.S sp|Q53FA7|QORX_HUMAN 1 958.5811 1.08 52169 19965 2 958.583845 480.2978 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3732.4 - 1.49E+06 - - - 2.8313 - 1.775 0.173 - 205.6 1 2 0 0.0027 9 0 0 0 5.75E+06 5.31E+06 - - - 1.978 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.19968.19968.2 0.0824 16-Sep R.GSLITSLLR[166.11].S sp|Q53FA7|QORX_HUMAN 1 968.5894 1.08 52172 19968 2 968.592695 485.302 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3732.8 - 1.37E+06 - - - 3.4008 - 1.942 0.255 - 188.2 1 2 0 0.0033 9 0 0 0 5.75E+06 5.31E+06 - - - 2.8436 1 230117_WJC_METTL3_WT_vs_EV_F06.19969.19969.2 8.53E-08 13/20 R.PMEVFMC[160.03]SVLK[136.11].R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1347.648 1.1 52173 19969 2 1347.648317 674.8313 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3732.9 - 1.28E+06 - - - 0.2078 - 2.671 0.574 - 721.7 1 1 0 0.0003 11 0 0 0 1.43E+07 1.30E+07 - - - 5.9382 1 230117_WJC_METTL3_WT_vs_EV_F06.19970.19970.2 1.03E-05 17/28 R.LPLPSPALEYTLGSR.L sp|Q8IU81|I2BP1_HUMAN 1 1612.8825 2.8 52174 19970 2 1612.884727 807.4485 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3733 - 1.28E+06 - - - 1.4068 - 2.86 0.428 - 759.1 1 2 0 0.0023 15 0 0 0 3.84E+07 1.37E+07 - - - 4.785 0.9343 230117_WJC_METTL3_WT_vs_EV_F06.19976.19976.2 0.377 20-Jul R.YVDQVLQLVYK[136.11].D sp|P11717|MPRI_HUMAN 1 1374.7639 -1 52180 19976 2 1374.770519 688.3892 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 5.83 3733.8 - 802668 - - - 4.8488 - 1.188 0.14 - 117 2 2 0 0.0067 11 0 0 0 0.00E+00 0.00E+00 - - - 0.4045 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.19978.19978.2 0.0143 20-Sep K.IIADIFEYTAK[136.11].H sp|P22033|MUTA_HUMAN 1 1290.6951 2.08 52182 19978 2 1290.697495 646.3548 "Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4" 4.37 3734.1 - 711255 - - - 1.8517 - 1.633 0.304 - 103.8 1 2 0 0.0024 11 0 0 0 5.29E+06 2.54E+06 - - - 2.6123 0.9907 230117_WJC_METTL3_WT_vs_EV_F06.19981.19981.2 1.16 12-Jun K.DFLLSLK[136.11].T sp|Q86UP2|KTN1_HUMAN 1 842.4993 1.05 52184 19981 2 842.500525 422.2569 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.84 3734.5 - 259824 - - - 1.4481 - 1.139 0.145 - 117.1 1 2 0 0.0012 7 0 0 0 2.48E+06 2.36E+06 - - - 0.524 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.19982.19982.2 0.000893 18-Nov R.DAVLLVFANK.Q "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 5 1088.623 1.93 52185 19982 2 1088.625837 545.3188 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 5.84 3734.6 - 1.83E+07 - - - 2.6097 - 2.314 0.391 - 532.8 1 2 0 0.0028 10 0 0 0 9.01E+07 4.66E+07 - - - 4.2699 1 230117_WJC_METTL3_WT_vs_EV_F06.19984.19984.2 1.03E-05 18-Sep R.DAVLLVFANK[136.11].Q "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 5 1096.6372 1.99 52187 19984 2 1096.63971 549.3259 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 5.84 3734.7 - 9.76E+06 - - - 2.2925 - 2.126 0.537 - 353.5 1 2 0 0.0025 10 0 0 0 8.65E+07 4.34E+07 - - - 5.1118 1 230117_WJC_METTL3_WT_vs_EV_F06.19986.19986.2 1.54E-08 13/20 R.PMEVFMC[160.03]SVLK.R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1339.6338 1.1 52189 19986 2 1339.636161 670.8242 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3734.8 - 4.35E+06 - - - 1.7348 - 2.682 0.666 - 705.9 1 1 0 0.0023 11 0 0 0 1.43E+07 1.30E+07 - - - 6.6282 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.19988.19988.2 4.09E-05 14-Sep R.YGLEC[160.03]LFR.Y "sp|Q6PKG0|LARP1_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN" 3 1056.5063 0.82 52191 19988 2 1056.509609 529.2604 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 5.99 3734.9 - 1.37E+06 - - - 3.1775 - 1.82 0.293 - 290.5 1 2 0 0.0034 8 0 0 0 7.98E+06 9.74E+06 - - - 3.0101 1 230117_WJC_METTL3_WT_vs_EV_F06.19989.19989.2 5.39E-05 18/30 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 8.42 52192 19989 2 1549.888517 775.9487 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3735.1 - 1.10E+06 - - - 3.6938 - 3.187 0.5 - 989.8 1 2 0 0.0057 16 0 0 0 2.45E+08 2.91E+07 - - - 5.5819 1 230117_WJC_METTL3_WT_vs_EV_F06.19991.19991.2 0.00143 13/28 R.LPLPSPALEYTLGSR[166.11].L sp|Q8IU81|I2BP1_HUMAN 1 1622.8907 2.8 52194 19991 2 1622.899727 812.4526 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3735.3 - 1.56E+06 - - - 5.545 - 2.401 0.487 - 382.8 1 2 0 0.009 15 0 0 0 3.84E+07 1.37E+07 - - - 4.7886 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.19993.19993.2 0.0396 14-Aug R.LLC[160.03]ELFIR[166.11].A "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN,tr|C9JCJ2|C9JCJ2_HUMAN,tr|C9J053|C9J053_HUMAN" 7 1072.5979 1.17 52196 19993 2 1072.601184 537.3062 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.99 3735.6 - 741898 - - - 3.1018 - 1.688 0.228 - 208.5 1 2 0 0.0033 8 0 0 0 1.64E+07 1.41E+07 - - - 2.3029 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.19994.19994.2 0.000373 18-Oct K.YFSSMAEFLK.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1221.574 1.22 52197 19994 2 1221.572418 611.7943 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 3735.7 - 712704 - - - -1.2926 - 1.858 0.475 - 217 1 2 0 -0.0016 10 0 0 0 3.13E+07 2.57E+07 - - - 4.2781 0.9925 230117_WJC_METTL3_WT_vs_EV_F06.19999.19999.2 0.00222 18/30 R.ALIAGGGAPEIELALR[166.11].L sp|P50991|TCPD_HUMAN 1 1559.8911 8.44 52202 19999 2 1559.901791 780.9528 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3736.4 - 197149 - - - 6.878 - 2.925 0.32 - 1126.5 1 2 0 0.0107 16 0 0 0 2.46E+08 2.91E+07 - - - 4.0399 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.20004.20004.2 0.0559 12-Sep R.WIVNLIR[166.11].N "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 15 922.5628 0.92 52206 20004 2 922.564921 462.2887 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 9.75 3736.8 - 5.89E+06 - - - 2.3077 - 1.532 0.287 - 472.8 1 2 0 0.0021 7 0 0 0 2.63E+07 2.84E+07 - - - 2.5117 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.20005.20005.2 0.0975 12-Aug R.WIVNLIR.N "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 15 912.5545 0.93 52207 20005 2 912.556551 457.2845 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 9.75 3736.9 - 4.52E+06 - - - 2.2234 - 1.458 0.22 - 384.9 1 2 0 0.002 7 0 0 0 2.63E+07 2.84E+07 - - - 1.86 1 230117_WJC_METTL3_WT_vs_EV_F06.20008.20008.2 1.03E-05 18-Nov R.VFYYLVQDLK.C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1286.6911 0.89 52210 20008 2 1286.694824 644.3528 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3737.1 - 2.46E+06 - - - 2.9137 - 2.359 0.482 - 424.4 1 2 0 0.0037 10 0 0 0 5.22E+07 5.88E+07 - - - 4.9955 0.996 230117_WJC_METTL3_WT_vs_EV_F06.20009.20009.2 0.00114 18-Oct R.YVEFNLLYDR.G "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1330.6558 1.24 52211 20009 2 1330.663372 666.3352 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.37 3737.2 - 8.25E+06 - - - 5.7265 - 1.844 0.417 - 247.8 1 2 0 0.0076 10 0 0 0 9.47E+06 7.61E+06 - - - 3.8267 1 230117_WJC_METTL3_WT_vs_EV_F06.20015.20015.2 0.000104 13/26 R.LEALLEAADPEVLR.R tr|D6RHC4|D6RHC4_HUMAN 1 1537.8352 2.01 52217 20015 2 1537.846371 769.9249 Ankyrin repeat and KH domain-containing protein 1 (Fragment) OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4 3738 - 695873 - - - 7.281 - 2.468 0.492 - 432.4 1 2 0 0.0112 14 0 0 0 2.10E+06 1.05E+06 - - - 4.9385 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.20022.20022.2 0.0459 16-Sep K.FFPLIEVNK.V "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1105.6172 0.84 52223 20022 2 1105.620349 553.8159 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6 3738.8 - 2.79E+06 - - - 2.8645 - 1.512 0.357 - 203.4 1 2 0 0.0032 9 0 0 0 1.48E+08 1.77E+08 - - - 2.8729 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20024.20024.2 0.0931 18-Oct R.YVEFNLLYDR[166.11].G "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1340.664 -1 52225 20024 2 1340.668157 671.3393 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.37 3739 - 3.63E+06 - - - 3.0843 - 2.162 0.424 - 306.1 1 2 0 0.0041 10 0 0 0 0.00E+00 0.00E+00 - - - 4.3236 1 230117_WJC_METTL3_WT_vs_EV_F06.20025.20025.3 2.20E-07 17/60 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 7.05 52226 20025 3 1549.885364 517.6349 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3739 - 3.21E+06 - - - 1.6595 - 2.921 0.486 - 502.9 1 2 0 0.0026 16 0 0 0 1.20E+07 1.71E+06 - - - 6.7081 0.9914 230117_WJC_METTL3_WT_vs_EV_F06.20026.20026.2 0.00764 14-Sep R.WLLSDYVK.V "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN,tr|C9JZH6|C9JZH6_HUMAN" 3 1022.5437 2.32 52227 20026 2 1022.542462 512.2791 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.83 3739.1 - 1.99E+06 - - - -1.1941 - 1.636 0.122 - 382.2 1 2 0 -0.0012 8 0 0 0 7.27E+06 3.13E+06 - - - 1.4263 1 230117_WJC_METTL3_WT_vs_EV_F06.20030.20030.2 3.87E-06 20-Dec K.DSLTLVFVETK[136.11].K "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1258.69 -1 52231 20030 2 1258.690702 630.3523 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3739.6 - 1.11E+06 - - - 0.5426 - 2.499 0.519 - 607.5 1 2 0 0.0007 11 0 0 0 0.00E+00 0.00E+00 - - - 5.3518 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.20033.20033.2 0.0103 12-Jun K.LFFLQVK[136.11].E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 901.5517 0.82 52234 20033 2 901.55303 451.7831 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3740 - 853537 - - - 1.503 - 1.386 0.288 - 100.2 1 2 0 0.0014 7 0 0 0 4.31E+06 5.28E+06 - - - 2.202 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.20034.20034.2 0.00703 13/26 K.IPPPVIMVQNVSFK.Y sp|Q9UG63|ABCF2_HUMAN 1 1567.8796 3.36 52235 20034 2 1567.879111 784.9471 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.75 3740.1 - 720105 - - - -0.3253 - 2.29 0.388 - 436.2 1 2 0 -0.0005 14 0 0 0 3.67E+06 1.09E+06 - - - 3.9858 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.20037.20037.2 0.144 20-Jun K.TYLQALPYFDR.L "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1385.698 -1 52238 20037 2 1385.697959 693.8563 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 5.5 3740.5 - 558343 - - - 0.0051 - 1.434 0.282 - 117.6 2 2 0 0 11 0 0 0 0.00E+00 0.00E+00 - - - 1.9645 1 230117_WJC_METTL3_WT_vs_EV_F06.20038.20038.2 6.43E-10 14/22 K.C[160.03]PLDPYFIMPDK.C "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 3 1494.6887 -1 52239 20038 2 1494.688323 748.3516 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4.21 3740.6 - 511052 - - - -0.2582 - 2.726 0.628 - 636.2 1 2 0 -0.0004 12 0 0 0 0.00E+00 0.00E+00 - - - 6.3179 1 230117_WJC_METTL3_WT_vs_EV_F06.20039.20039.3 2.11E-07 17/52 K.IPPPVIMVQNVSFK.Y sp|Q9UG63|ABCF2_HUMAN 1 1567.8796 4.12 52240 20039 3 1567.880836 523.6338 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.75 3740.8 - 489998 - - - 0.7749 - 3.013 0.52 - 487.1 1 2 0 0.0012 14 0 0 0 2.21E+06 5.37E+05 - - - 7.2682 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20046.20046.3 0.00722 16/40 R.AALLELWELR[166.11]R[166.11].Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1388.8043 0.78 52246 20046 3 1388.805486 463.942 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.19 3741.6 - 2.32E+06 - - - 0.8468 - 2.387 0.287 - 590.1 1 2 0 0.0012 11 0 0 0 3.69E+06 4.75E+06 - - - 4.2111 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20048.20048.2 1.45E-05 16-Oct R.LTSFITVFK.Y "sp|Q13617|CUL2_HUMAN,tr|Q5T2B5|Q5T2B5_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 3 1054.6063 1.97 52248 20048 2 1054.608624 528.3104 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 8.75 3741.8 - 1.62E+06 - - - 2.2198 - 2.284 0.296 - 282 1 2 0 0.0023 9 0 0 0 6.11E+06 3.10E+06 - - - 3.616 0.9901 230117_WJC_METTL3_WT_vs_EV_F06.20049.20049.2 0.859 14-Jul R.LLLEDLVK.K "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 941.5797 1.46 52249 20049 2 941.581023 471.7971 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 4.37 3741.9 - 1.57E+06 - - - 1.369 - 1.156 0.135 - 117.7 1 2 0 0.0013 8 0 0 0 3.12E+06 2.14E+06 - - - 0.4749 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.20050.20050.2 0.18 12-Jun K.LFFLQVK.E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 893.5375 0.82 52250 20050 2 893.538639 447.776 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3742.1 - 1.52E+06 - - - 1.3027 - 1.419 0.173 - 95.5 1 2 0 0.0012 7 0 0 0 4.31E+06 5.28E+06 - - - 1.4273 1 230117_WJC_METTL3_WT_vs_EV_F06.20055.20055.2 1.58E-09 24-Dec R.FADALGLELAQVK.V sp|O95685|PPR3D_HUMAN 1 1373.7555 9.43 52255 20055 2 1373.756368 687.885 Protein phosphatase 1 regulatory subunit 3D OS=Homo sapiens OX=9606 GN=PPP1R3D PE=1 SV=1 4.37 3742.7 - 559731 - - - 0.6559 - 2.674 0.589 - 339.3 1 2 0 0.0009 13 0 0 0 1.65E+06 1.75E+05 - - - 5.9154 1 230117_WJC_METTL3_WT_vs_EV_F06.20058.20058.2 3.04E-06 20-Nov K.LLVYEALEYAK.R "sp|Q96DB5|RMD1_HUMAN,tr|H0YB83|H0YB83_HUMAN,tr|E5RH53|E5RH53_HUMAN,tr|H0YB03|H0YB03_HUMAN" 4 1310.7122 0.03 52258 20058 2 1310.714728 656.3634 Regulator of microtubule dynamics protein 1 OS=Homo sapiens OX=9606 GN=RMDN1 PE=1 SV=1 4.53 3743.1 - 462377 - - - 1.9249 - 2.178 0.53 - 401.4 1 2 0 0.0025 11 0 0 0 1.54E+06 5.02E+07 - - - 5.0606 0.9929 230117_WJC_METTL3_WT_vs_EV_F06.20064.20064.2 0.625 12-Jul K.WLFTEIR.S "sp|P50851|LRBA_HUMAN,tr|E9PEM5|E9PEM5_HUMAN,tr|A0A494BZW2|A0A494BZW2_HUMAN,tr|A0A494C1L5|A0A494C1L5_HUMAN,tr|H0YAC6|H0YAC6_HUMAN" 5 963.5178 0.96 52263 20064 2 963.519041 482.7662 Lipopolysaccharide-responsive and beige-like anchor protein OS=Homo sapiens OX=9606 GN=LRBA PE=1 SV=4 6 3744 - 133311 - - - 1.2859 - 1.209 0.145 - 156.7 1 2 0 0.0012 7 0 0 0 9.62E+05 1.00E+06 - - - 0.713 0.9883 230117_WJC_METTL3_WT_vs_EV_F06.20066.20066.2 0.0076 22-Nov K.LGAIFLEGVTVK.G sp|O60942|MCE1_HUMAN 1 1245.7333 7.19 52265 20066 2 1245.743203 623.8739 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 6 3744.3 - 2.05E+06 - - - 7.9696 - 2.323 0.408 - 418.2 1 2 0 0.0099 12 0 0 0 6.41E+06 8.91E+05 - - - 4.2691 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.20068.20068.2 0.592 20-Aug R.YLLLLAAGDPR.E "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1200.6867 8.43 52267 20068 2 1200.689321 601.3506 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.84 3744.5 - 698082 - - - 2.2171 - 1.856 0.128 - 166.2 1 2 0 0.0027 11 0 0 0 3.20E+06 3.80E+05 - - - 1.6586 0.9946 230117_WJC_METTL3_WT_vs_EV_F06.20069.20069.2 0.261 12-Jul R.IIWQFIK.E "sp|P48735|IDHP_HUMAN,tr|H0YL11|H0YL11_HUMAN" 2 946.564 1.85 52268 20069 2 946.567008 474.2893 "Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2" 8.75 3744.6 - 671165 - - - 3.1525 - 1.259 0.23 - 131.4 1 2 0 0.003 7 0 0 0 2.69E+06 1.46E+06 - - - 1.4686 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.20071.20071.2 0.00958 14-Aug K.AIFLFVDK.T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 951.543 1.45 52270 20071 2 951.546263 476.7788 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3744.9 - 554841 - - - 3.4775 - 1.512 0.346 - 212.8 1 2 0 0.0033 8 0 0 0 5.85E+06 4.03E+06 - - - 2.8424 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.20072.20072.2 0.0185 14-Aug K.AIFLFVDK[136.11].T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 959.5572 1.45 52271 20072 2 959.560624 480.7859 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3745 - 476250 - - - 3.6163 - 1.501 0.36 - 245.1 1 2 0 0.0035 8 0 0 0 5.85E+06 4.03E+06 - - - 2.9237 1 230117_WJC_METTL3_WT_vs_EV_F06.20073.20073.3 2.83E-08 18/72 K.LGGSLADSYLDEGFLLDKK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2040.0415 1.51 52272 20073 3 2040.050035 681.0211 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.23 3745.2 - 453719 - - - 4.1651 - 3.312 0.609 - 352.3 1 2 0 0.0085 19 0 0 0 1.56E+06 1.03E+06 - - - 8.2695 1 230117_WJC_METTL3_WT_vs_EV_F06.20078.20078.2 0.000496 22-Nov Y.VLNPLAPEFIPR.A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1364.7816 -1 52277 20078 2 1364.789853 683.3981 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.97 3745.8 - 244573 - - - 6.031 - 2.368 0.459 - 338.9 1 1 0 0.0082 12 0 0 0 0.00E+00 0.00E+00 - - - 4.6968 1 230117_WJC_METTL3_WT_vs_EV_F06.20088.20088.2 0.000777 14/22 R.ALLANALTSALR.L "sp|P57088|TMM33_HUMAN,tr|D6RAA6|D6RAA6_HUMAN" 2 1212.719 1.2 52286 20088 2 1212.7228 607.3668 Transmembrane protein 33 OS=Homo sapiens OX=9606 GN=TMEM33 PE=1 SV=2 9.79 3747 - 1.75E+06 - - - 3.1161 - 2.823 0.455 - 725.1 1 2 0 0.0038 12 0 0 0 1.11E+07 9.29E+06 - - - 5.1311 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.20089.20089.2 0.0696 15/22 R.ALLANALTSALR[166.11].L "sp|P57088|TMM33_HUMAN,tr|D6RAA6|D6RAA6_HUMAN" 2 1222.7273 1.23 52287 20089 2 1222.731493 612.3709 Transmembrane protein 33 OS=Homo sapiens OX=9606 GN=TMEM33 PE=1 SV=2 9.79 3747 - 1.67E+06 - - - 3.4366 - 2.359 0.216 - 1086.8 1 2 0 0.0042 12 0 0 0 1.09E+07 8.83E+06 - - - 2.8932 1 230117_WJC_METTL3_WT_vs_EV_F06.20090.20090.2 0.000289 18-Oct R.FC[160.03]IWTESAFR[166.11].K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1325.6102 0.86 52288 20090 2 1325.613473 663.8124 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3747.1 - 922014 - - - 2.4592 - 2.14 0.48 - 412.9 1 2 0 0.0033 10 0 0 0 7.18E+06 8.34E+06 - - - 4.7089 0.999 230117_WJC_METTL3_WT_vs_EV_F06.20092.20092.2 0.0262 18-Aug R.DIIALNPLYR.E "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN" 3 1186.671 -1 52290 20092 2 1186.673849 594.3428 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 5.84 3747.3 - 796672 - - - 2.3932 - 1.886 0.249 - 204.7 1 2 0 0.0028 10 0 0 0 0.00E+00 0.00E+00 - - - 2.6502 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20094.20094.2 0.0122 18-Oct R.FC[160.03]IWTESAFR.K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1315.6019 0.87 52292 20094 2 1315.60569 658.8082 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3747.5 - 661316 - - - 2.8481 - 2.079 0.399 - 360.7 1 2 0 0.0037 10 0 0 0 7.27E+06 8.34E+06 - - - 4.0298 0.9947 230117_WJC_METTL3_WT_vs_EV_F06.20096.20096.2 0.788 12-Aug R.IIWELIK[136.11].E "sp|O75874|IDHC_HUMAN,tr|C9JLU6|C9JLU6_HUMAN,tr|C9J4N6|C9J4N6_HUMAN,tr|C9JJE5|C9JJE5_HUMAN" 4 921.5779 7.15 52294 20096 2 921.580687 461.7962 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 6 3747.7 - 633581 - - - 3.035 - 1.397 0.178 - 161.6 1 2 0 0.0028 7 0 0 0 1.61E+07 2.26E+06 - - - 1.4142 0.9947 230117_WJC_METTL3_WT_vs_EV_F06.20106.20106.2 1.57 14-Aug K.ALIIIWAK[136.11].V "sp|P57678|GEMI4_HUMAN,tr|I3L4M4|I3L4M4_HUMAN,tr|E7EN12|E7EN12_HUMAN,tr|I3L4A4|I3L4A4_HUMAN,tr|I3L2C7|I3L2C7_HUMAN,tr|I3L399|I3L399_HUMAN" 6 934.6095 -1 52303 20106 2 934.612162 468.312 Gem-associated protein 4 OS=Homo sapiens OX=9606 GN=GEMIN4 PE=1 SV=2 8.8 3749.1 - 234319 - - - 2.8226 - 1.568 0.124 - 170.4 1 2 0 0.0026 8 0 0 0 0.00E+00 0.00E+00 - - - 1.3126 0.9876 230117_WJC_METTL3_WT_vs_EV_F06.20108.20108.2 0.00854 18-Nov R.DLASVQALLR.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1084.6241 0.39 52305 20108 2 1084.632032 543.3193 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3749.3 - 2.88E+06 - - - 7.3519 - 2.22 0.314 - 433.4 1 2 0 0.008 10 0 0 0 1.31E+07 3.33E+07 - - - 3.5838 0.9562 230117_WJC_METTL3_WT_vs_EV_F06.20109.20109.2 2.31 12-Jul R.TLLEFLK[136.11].R "sp|Q14232|EI2BA_HUMAN,tr|F5H0D0|F5H0D0_HUMAN,tr|H0YGG4|H0YGG4_HUMAN" 3 870.5306 1.02 52306 20109 2 870.535228 436.2726 Translation initiation factor eIF-2B subunit alpha OS=Homo sapiens OX=9606 GN=EIF2B1 PE=1 SV=1 5.66 3749.4 - 2.16E+06 - - - 5.3106 - 1.372 0.121 - 145.1 1 2 0 0.0046 7 0 0 0 8.15E+06 8.00E+06 - - - 0.9354 0.99 230117_WJC_METTL3_WT_vs_EV_F06.20113.20113.2 0.0386 14-Sep K.QDILTIFK[136.11].R "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV8|B0QYV8_HUMAN" 2 984.5735 1.77 52310 20113 2 984.58032 493.294 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3749.9 - 863533 - - - 6.8933 - 1.868 0.351 - 238.6 1 2 0 0.0068 8 0 0 0 1.62E+07 9.12E+06 - - - 3.5159 0.9845 230117_WJC_METTL3_WT_vs_EV_F06.20114.20114.2 0.0114 12-Jun R.YGLVFFR[166.11].Q "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN,tr|F6WRY4|F6WRY4_HUMAN" 4 910.494 1.37 52311 20114 2 910.498189 456.2543 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.75 3750.1 - 813719 - - - 4.5525 - 1.486 0.145 - 139.4 1 2 0 0.0041 7 0 0 0 4.34E+06 3.16E+06 - - - 1.3657 1 230117_WJC_METTL3_WT_vs_EV_F06.20116.20116.2 2.78E-05 22-Dec K.FLQDTIEEMALK[136.11].N sp|O95202|LETM1_HUMAN 1 1444.7363 4.21 52313 20116 2 1444.740936 723.3754 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.14 3750.3 - 678847 - - - 3.1964 - 2.52 0.471 - 412.5 1 2 0 0.0046 12 0 0 0 1.35E+07 3.21E+06 - - - 4.9502 0.9655 230117_WJC_METTL3_WT_vs_EV_F06.20124.20124.2 0.182 22-Jul K.LLPELLQPYTER[166.11].V sp|Q13057|COASY_HUMAN 1 1480.8165 -1 52321 20124 2 1480.824502 741.4155 Bifunctional coenzyme A synthase OS=Homo sapiens OX=9606 GN=COASY PE=1 SV=4 4.53 3751.4 - 152220 - - - 5.4038 - 1.528 0.138 - 158.5 1 2 0 0.008 12 0 0 0 0.00E+00 0.00E+00 - - - 1.1733 0.98 230117_WJC_METTL3_WT_vs_EV_F06.20128.20128.2 0.00373 20-Aug K.LFPGFEIETVK.N "sp|P08243|ASNS_HUMAN,tr|F8WEJ5|F8WEJ5_HUMAN" 2 1278.686 -1 52324 20128 2 1278.696835 640.3503 Asparagine synthetase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=ASNS PE=1 SV=4 4.53 3751.8 - 154355 - - - 8.4814 - 1.633 0.429 - 145.1 1 2 0 0.0108 11 0 0 0 0.00E+00 0.00E+00 - - - 3.5329 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20132.20132.2 0.0275 14-Aug K.EILIPVFK[136.11].N sp|P53396|ACLY_HUMAN 1 965.6041 1.37 52328 20132 2 965.605537 483.8093 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3752.1 - 571693 - - - 1.483 - 1.521 0.398 - 213.9 1 2 0 0.0014 8 0 0 0 4.76E+07 3.48E+07 - - - 3.245 0.999 230117_WJC_METTL3_WT_vs_EV_F06.20133.20133.2 0.158 14-Jul K.EILIPVFK.N sp|P53396|ACLY_HUMAN 1 957.5899 1.37 52329 20133 2 957.591693 479.8022 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3752.2 - 556397 - - - 1.8672 - 1.606 0.275 - 169.3 1 2 0 0.0018 8 0 0 0 4.76E+07 3.48E+07 - - - 2.5004 1 230117_WJC_METTL3_WT_vs_EV_F06.20134.20134.2 4.55E-06 20-Oct R.FSYLAVIEGAK[136.11].F "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 1204.6583 1.58 52330 20134 2 1204.662409 603.3364 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 6 3752.3 - 415001 - - - 3.3902 - 2.093 0.564 - 275.4 1 2 0 0.0041 11 0 0 0 6.79E+06 4.30E+06 - - - 5.2035 1 230117_WJC_METTL3_WT_vs_EV_F06.20137.20137.2 0.000944 14/26 K.ALLAVIGADSVTLK.N sp|Q9NYH9|UTP6_HUMAN 1 1369.8181 1.34 52333 20137 2 1369.822858 685.9163 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3752.6 - 203428 - - - 3.4975 - 2.888 0.431 - 755 1 2 0 0.0048 14 0 0 0 3.78E+06 2.81E+06 - - - 4.8843 0.9941 230117_WJC_METTL3_WT_vs_EV_F06.20138.20138.2 0.308 12-May R.WFVFDAR.R sp|Q9UPU7|TBD2B_HUMAN 1 939.4603 1.07 52334 20138 2 939.463015 470.7374 TBC1 domain family member 2B OS=Homo sapiens OX=9606 GN=TBC1D2B PE=1 SV=2 5.84 3752.7 - 189333 - - - 2.9038 - 1.087 0.266 - 86.7 1 2 0 0.0027 7 0 0 0 1.04E+06 9.67E+05 - - - 1.2691 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20139.20139.2 0.0244 13/26 K.ALLAVIGADSVTLK[136.11].N sp|Q9NYH9|UTP6_HUMAN 1 1377.8323 1.34 52335 20139 2 1377.834653 689.9234 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3752.9 - 176089 - - - 1.7317 - 2.657 0.357 - 693.8 1 2 0 0.0024 14 0 0 0 3.78E+06 2.81E+06 - - - 4.1293 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.20141.20141.2 0.00134 22-Sep K.LLPELLQPYTER.V sp|Q13057|COASY_HUMAN 1 1470.8082 1.98 52337 20141 2 1470.807666 736.4114 Bifunctional coenzyme A synthase OS=Homo sapiens OX=9606 GN=COASY PE=1 SV=4 4.53 3753.1 - 102074 - - - -0.3835 - 2.008 0.393 - 317 1 2 0 -0.0006 12 0 0 0 1.20E+06 6.09E+05 - - - 3.7778 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.20146.20146.2 0.822 18-Oct K.LGLFPSNFVK.E sp|Q9Y5K6|CD2AP_HUMAN 1 1120.6281 1.61 52341 20146 2 1120.629569 561.3213 CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1 8.75 3753.8 - 612626 - - - 1.3278 - 1.762 0.26 - 227.2 1 2 0 0.0015 10 0 0 0 6.83E+06 4.25E+06 - - - 2.542 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20148.20148.2 0.036 18-Nov R.LTTLELLEVR[166.11].R "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1195.7052 0.71 52342 20148 2 1195.708626 598.8599 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.53 3754 - 2.60E+06 - - - 2.8995 - 2.285 0.394 - 553.4 1 2 0 0.0035 10 0 0 0 1.98E+07 2.80E+07 - - - 4.2566 1 230117_WJC_METTL3_WT_vs_EV_F06.20149.20149.2 9.93E-05 20-Nov R.AFITNIPFDVK[136.11].W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1271.7005 2.47 52343 20149 2 1271.704736 636.8575 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3754 - 3.93E+06 - - - 3.3121 - 2.085 0.496 - 481.9 1 2 0 0.0042 11 0 0 0 4.84E+08 1.96E+08 - - - 4.6909 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.20154.20154.2 0.00715 12-Aug R.YGLVFFR.Q "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN,tr|F6WRY4|F6WRY4_HUMAN" 4 900.4858 1.34 52348 20154 2 900.487625 451.2502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.75 3754.4 - 653379 - - - 2.0556 - 1.813 0.259 - 213.1 1 2 0 0.0019 7 0 0 0 4.20E+06 3.13E+06 - - - 2.8386 1 230117_WJC_METTL3_WT_vs_EV_F06.20155.20155.2 5.68E-08 14/26 K.LLTGELLPTDGMIR.K sp|Q9UG63|ABCF2_HUMAN 1 1527.8331 2.4 52349 20155 2 1527.838392 764.9238 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.37 3754.5 - 555639 - - - 3.4866 - 2.745 0.508 - 499.1 1 2 0 0.0053 14 0 0 0 1.32E+07 5.49E+06 - - - 5.3254 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.20156.20156.2 0.0977 12-Jun R.DVFLMLK[136.11].K "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 872.4921 1.1 52350 20156 2 872.494789 437.2533 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 5.84 3754.6 - 536393 - - - 3.0694 - 1.338 0.282 - 139.6 1 2 0 0.0027 7 0 0 0 3.26E+06 2.97E+06 - - - 2.0456 1 230117_WJC_METTL3_WT_vs_EV_F06.20158.20158.2 2.69E-08 18/28 L.LVSVSALTLATETVR.S sp|P50991|TCPD_HUMAN 1 1558.893 15.13 52352 20158 2 1558.896845 780.4538 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6 3754.8 - 489867 - - - 2.4517 - 3.151 0.626 - 1338.2 1 1 0 0.0038 15 0 0 0 5.94E+06 3.93E+05 - - - 6.4852 1 230117_WJC_METTL3_WT_vs_EV_F06.20160.20160.2 3.51E-07 14/24 R.ALDPAAAAYLFQR.Q "sp|O75376|NCOR1_HUMAN,tr|E7EVK1|E7EVK1_HUMAN" 2 1405.7354 2.48 52354 20160 2 1405.739208 703.875 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 5.88 3755 - 417983 - - - 2.7089 - 3.021 0.47 - 977.6 1 2 0 0.0038 13 0 0 0 2.11E+06 8.48E+05 - - - 5.3487 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20166.20166.2 0.00508 18-Aug K.MPETDFLIIR.T "sp|Q8IZX4|TAF1L_HUMAN,sp|P21675|TAF1_HUMAN,tr|A0A804HK58|A0A804HK58_HUMAN,tr|A0A804HHS0|A0A804HHS0_HUMAN,tr|A0A804HIY8|A0A804HIY8_HUMAN,tr|A0A804HIC2|A0A804HIC2_HUMAN" 6 1233.6427 0.23 52360 20166 2 1233.64391 617.8286 Transcription initiation factor TFIID subunit 1-like OS=Homo sapiens OX=9606 GN=TAF1L PE=1 SV=1 4.37 3755.8 - 97795.5 - - - 0.9444 - 1.838 0.377 - 148.9 1 2 0 0.0012 10 0 0 0 1.57E+06 6.70E+06 - - - 3.5242 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.20169.20169.2 0.0164 18-Aug R.DLASVQALLR[166.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1094.6323 0.78 52362 20169 2 1094.63519 548.3234 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3756.1 - 1.55E+06 - - - 2.6146 - 1.671 0.202 - 207.2 1 2 0 0.0029 10 0 0 0 1.20E+07 1.53E+07 - - - 1.9652 0.9814 230117_WJC_METTL3_WT_vs_EV_F06.20170.20170.2 1.59 14-Jul R.LLLTPWVK[136.11].F sp|Q14152|EIF3A_HUMAN 1 976.6201 0.91 52363 20170 2 976.621476 489.3173 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.75 3756.1 - 4.49E+06 - - - 1.4202 - 1.395 0.001 - 111.1 1 2 0 0.0014 8 0 0 0 2.11E+07 2.31E+07 - - - 0.0519 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20174.20174.2 0.0101 16-Aug R.ALQLLYDLR.Y "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1103.6339 1.14 52367 20174 2 1103.635264 552.8242 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.88 3756.3 - 1.49E+06 - - - 1.2404 - 1.872 0.326 - 269.9 1 2 0 0.0014 9 0 0 0 6.31E+06 5.53E+06 - - - 3.2624 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20175.20175.2 0.000834 16-Oct K.LGFMSAFVK[136.11].A "sp|P36957|ODO2_HUMAN,tr|Q86SW4|Q86SW4_HUMAN" 2 1006.5401 0.66 52368 20175 2 1006.540183 504.2773 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 8.75 3756.4 - 1.41E+06 - - - 0.0586 - 2.025 0.386 - 237.9 1 2 0 0.0001 9 0 0 0 5.13E+06 7.83E+06 - - - 3.9332 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.20177.20177.2 0.00053 20-Nov R.ELGLGLGLGLK.E "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 1068.6543 1.17 52370 20177 2 1068.657308 535.3344 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 6.1 3756.5 - 1.32E+06 - - - 2.8185 - 1.761 0.405 - 309.5 1 2 0 0.003 11 0 0 0 6.73E+06 5.77E+06 - - - 3.5622 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.20179.20179.3 0.175 Jun-44 R.LLHLPLSLTALK.L sp|Q9BTT6|LRRC1_HUMAN 1 1317.8384 3.01 52372 20179 3 1317.840629 440.2867 Leucine-rich repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRRC1 PE=1 SV=1 8.76 3756.6 - 1.03E+06 - - - 1.6853 - 1.503 0.269 - 57.1 1 2 0 0.0022 12 0 0 0 3.48E+06 1.16E+06 - - - 2.6679 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.20181.20181.2 0.00854 20-Jul R.LLTGWMPTAIR.G "sp|Q12769|NU160_HUMAN,tr|E9PR16|E9PR16_HUMAN,tr|G3V198|G3V198_HUMAN" 3 1257.6904 0.26 52374 20181 2 1257.694096 629.8525 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 9.75 3756.8 - 916318 - - - 2.9673 - 1.682 0.455 - 178.8 1 2 0 0.0037 11 0 0 0 4.04E+06 1.54E+07 - - - 3.8071 1 230117_WJC_METTL3_WT_vs_EV_F06.20183.20183.2 2.83E-05 22-Dec K.MFIGGLSWDTTK[136.11].K "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 1362.6733 1.13 52376 20183 2 1362.671841 682.3439 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 5.59 3757 - 567743 - - - -1.0876 - 2.15 0.517 - 382.9 1 2 0 -0.0015 12 0 0 0 1.91E+07 1.70E+07 - - - 4.8732 0.9392 230117_WJC_METTL3_WT_vs_EV_F06.20185.20185.2 0.000447 28-Aug R.LLPYLVAANPVNYGR.P sp|Q9UJK0|TSR3_HUMAN 1 1658.9144 2.66 52378 20185 2 1658.919513 830.4645 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.59 3757.3 - 421637 - - - 3.0659 - 1.86 0.392 - 197.1 1 1 0 0.0051 15 0 0 0 1.79E+06 6.73E+05 - - - 3.4604 1 230117_WJC_METTL3_WT_vs_EV_F06.20190.20190.2 3.92E-08 13/24 K.ILTFDQLALDSPK[136.11].G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1467.8064 0.73 52381 20190 2 1467.807565 734.9105 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3758.1 - 1.74E+06 - - - 0.7624 - 2.716 0.51 - 533.8 1 2 0 0.0011 13 0 0 0 7.38E+07 1.01E+08 - - - 5.3719 1 230117_WJC_METTL3_WT_vs_EV_F06.20191.20191.2 7.25E-05 15/24 K.ILTFDQLALDSPK.G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1459.7922 0.73 52382 20191 2 1459.794749 730.9034 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3758.2 - 1.21E+06 - - - 1.7146 - 2.805 0.547 - 776.3 1 2 0 0.0025 13 0 0 0 7.38E+07 1.01E+08 - - - 5.7275 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.20192.20192.2 0.0396 20-Nov R.VLPSIVNEVLK.S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1209.7333 1.28 52383 20192 2 1209.739285 605.8739 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3758.3 - 1.27E+06 - - - 4.968 - 1.725 0.367 - 358.8 1 2 0 0.006 11 0 0 0 2.33E+07 1.81E+07 - - - 3.2247 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.20193.20193.2 0.00141 20-Nov R.LLGDLLPEAVR[166.11].F sp|Q9H1B7|I2BPL_HUMAN 1 1204.7055 8.05 52384 20193 2 1204.709416 603.36 Probable E3 ubiquitin-protein ligase IRF2BPL OS=Homo sapiens OX=9606 GN=IRF2BPL PE=1 SV=1 4.37 3758.4 - 748018 - - - 3.2564 - 2.163 0.267 - 268.4 1 2 0 0.0039 11 0 0 0 2.30E+07 2.85E+06 - - - 3.0989 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.20194.20194.2 0.000212 16-Oct R.DGFVC[160.03]ALLR.F "sp|Q8WUY1|THEM6_HUMAN,tr|H0YAR9|H0YAR9_HUMAN" 2 1049.5328 1.2 52385 20194 2 1049.53015 525.7737 Protein THEM6 OS=Homo sapiens OX=9606 GN=THEM6 PE=1 SV=2 5.83 3758.6 - 740312 - - - -2.5259 - 1.838 0.442 - 264.9 1 2 0 -0.0027 9 0 0 0 4.00E+06 3.32E+06 - - - 4.0657 0.978 230117_WJC_METTL3_WT_vs_EV_F06.20201.20201.3 0.0946 Aug-40 R.AFITNIPFDVK.W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1263.6863 3.84 52392 20201 3 1263.691925 422.2361 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3759.5 - 154085 - - - 4.4323 - 1.204 0.26 - 72.3 1 2 0 0.0056 11 0 0 0 1.07E+06 2.80E+05 - - - 1.9646 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.20206.20206.2 0.000923 14-Aug R.DWVLNEFR[166.11].S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1087.5326 1.11 52395 20206 2 1087.53633 544.7736 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3760.1 - 280677 - - - 3.4169 - 1.763 0.3 - 387.2 1 2 0 0.0037 8 0 0 0 1.74E+07 1.58E+07 - - - 2.9657 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.20207.20207.3 0.000208 14/40 K.LLPQFLLHLDK[136.11].L "sp|Q8N4J0|CARME_HUMAN,tr|Q5T8V1|Q5T8V1_HUMAN,tr|Q5T8U9|Q5T8U9_HUMAN" 3 1343.8057 1.4 52396 20207 3 1343.80788 448.9425 Carnosine N-methyltransferase OS=Homo sapiens OX=9606 GN=CARNMT1 PE=1 SV=1 6.74 3760.3 - 162070 - - - 1.6535 - 2.153 0.433 - 270.6 1 2 0 0.0022 11 0 0 0 2.88E+06 2.05E+06 - - - 5.5454 0.992 230117_WJC_METTL3_WT_vs_EV_F06.20214.20214.2 9.70E-05 14-Aug R.DWVLNEFR.S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1077.5243 1.1 52403 20214 2 1077.532085 539.7694 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3761.1 - 182354 - - - 7.1841 - 1.764 0.48 - 319.7 1 2 0 0.0077 8 0 0 0 1.74E+07 1.58E+07 - - - 4.2957 0.981 230117_WJC_METTL3_WT_vs_EV_F06.20223.20223.2 0.13 12-Aug R.FVFLLDR.G sp|Q13045|FLII_HUMAN 1 908.512 1.48 52410 20223 2 908.515839 455.2633 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3762.3 - 1.65E+06 - - - 4.2377 - 1.588 0.071 - 247.4 1 2 0 0.0039 7 0 0 0 6.40E+06 4.31E+06 - - - 1.0296 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.20224.20224.2 0.000192 20-Oct R.VLPSIVNEVLK[136.11].S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1217.7475 1.3 52411 20224 2 1217.752267 609.881 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3762.5 - 1.96E+06 - - - 3.9351 - 1.977 0.46 - 340.6 1 2 0 0.0048 11 0 0 0 2.32E+07 1.78E+07 - - - 4.2809 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.20227.20227.2 0.0799 18-Sep R.LFALVLTPTR[166.11].E sp|Q9H0S4|DDX47_HUMAN 1 1139.6942 1 52414 20227 2 1139.698199 570.8544 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 9.75 3762.9 - 1.20E+06 - - - 3.5088 - 2.043 0.399 - 226.3 1 2 0 0.004 10 0 0 0 7.58E+06 7.56E+06 - - - 3.9809 0.9885 230117_WJC_METTL3_WT_vs_EV_F06.20228.20228.2 0.035 12-Jul R.FVFLLDR[166.11].G sp|Q13045|FLII_HUMAN 1 918.5203 1.48 52415 20228 2 918.522928 460.2674 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3763 - 1.20E+06 - - - 2.9058 - 1.455 0.072 - 192.6 1 2 0 0.0027 7 0 0 0 6.40E+06 4.31E+06 - - - 0.7602 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.20230.20230.3 3.79E-05 18/48 R.WLPLGLGLNHLGK.G "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1416.8242 1.83 52417 20230 3 1416.831202 473.282 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 8.76 3763.2 - 849962 - - - 4.9738 - 2.953 0.365 - 461.5 1 2 0 0.007 13 0 0 0 3.19E+06 1.75E+06 - - - 5.5433 1 230117_WJC_METTL3_WT_vs_EV_F06.20236.20236.2 2.46E-09 16/20 R.IPDQLVILDMK.H "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1283.7159 1.34 52423 20236 2 1283.721017 642.8652 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.21 3764 - 432960 - - - 3.9783 - 3.105 0.429 - 1258.1 1 2 0 0.0051 11 0 0 0 1.39E+07 1.04E+07 - - - 5.2731 0.9961 230117_WJC_METTL3_WT_vs_EV_F06.20238.20238.2 0.000334 16-Sep K.FPEILATLR.G sp|P54198|HIRA_HUMAN 1 1058.6124 6.11 52425 20238 2 1058.618327 530.3135 Protein HIRA OS=Homo sapiens OX=9606 GN=HIRA PE=1 SV=2 6 3764.3 - 299199 - - - 5.5696 - 1.92 0.37 - 225.1 1 2 0 0.0059 9 0 0 0 3.44E+06 5.63E+05 - - - 3.6592 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20239.20239.2 6.03E-05 28-Sep K.ELVGPPLAETVFTPK.T sp|P49792|RBP2_HUMAN 1 1596.8763 1.99 52426 20239 2 1596.879633 799.4454 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3764.4 - 298568 - - - 2.0809 - 1.702 0.452 - 183.1 1 2 0 0.0033 15 0 0 0 2.35E+06 1.18E+06 - - - 3.6859 1 230117_WJC_METTL3_WT_vs_EV_F06.20243.20243.2 0.000179 14/20 R.AFITNIPFDVK.W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1263.6863 2.47 52429 20243 2 1263.691357 632.8504 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3764.9 - 5.49E+07 - - - 3.9828 - 2.302 0.482 - 767.2 1 2 0 0.005 11 0 0 0 4.86E+08 1.97E+08 - - - 4.855 0.9621 230117_WJC_METTL3_WT_vs_EV_F06.20245.20245.2 0.00156 22-Sep K.AAAIGIDLGTTY.S "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1164.6027 - 52431 20245 2 1164.605584 583.3086 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 3.8 3765.1 - 3.25E+06 - - - 2.5159 - 2.033 0.387 - 318.9 1 1 0 0.0029 12 0 0 0 - - - - - 3.7653 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20246.20246.2 0.0262 14-Sep K.VNLAELFK.G sp|P30044|PRDX5_HUMAN 1 932.5331 2.08 52432 20246 2 932.534704 467.2738 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.97 3765.2 - 2.10E+06 - - - 1.7007 - 1.963 0.354 - 287.2 1 2 0 0.0016 8 0 0 0 2.11E+07 1.02E+07 - - - 3.6893 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.20247.20247.2 0.0469 14-Jun K.VNLAELFK[136.11].G sp|P30044|PRDX5_HUMAN 1 940.5473 2.06 52433 20247 2 940.550091 471.2809 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.97 3765.3 - 1.21E+06 - - - 2.9483 - 1.667 0.376 - 101.6 1 2 0 0.0028 8 0 0 0 2.11E+07 1.02E+07 - - - 3.3585 1 230117_WJC_METTL3_WT_vs_EV_F06.20248.20248.2 0.000145 15/20 R.IPDQLVILDMK[136.11].H "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1291.7301 1.33 52434 20248 2 1291.732338 646.8723 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.21 3765.4 - 1.15E+06 - - - 1.7248 - 3.039 0.494 - 1150 1 2 0 0.0022 11 0 0 0 1.38E+07 1.04E+07 - - - 5.6959 0.9849 230117_WJC_METTL3_WT_vs_EV_F06.20252.20252.2 0.205 16-Aug R.DNALTLLIK[136.11].A "sp|Q9H3U1|UN45A_HUMAN,tr|A0A1W2PNX8|A0A1W2PNX8_HUMAN" 2 1007.6106 -1 52438 20252 2 1007.613503 504.8126 Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1 5.84 3765.9 - 404923 - - - 2.8344 - 1.546 0.032 - 170.4 1 2 0 0.0029 9 0 0 0 0.00E+00 0.00E+00 - - - 0.5369 0.8685 230117_WJC_METTL3_WT_vs_EV_F06.20255.20255.2 0.234 22-Jun R.NVYPEEMIVALR.E sp|Q5VT52|RPRD2_HUMAN 1 1432.7384 14.17 52441 20255 2 1432.730531 717.3765 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3766.3 - 283243 - - - -5.5174 - 1.273 0.222 - 69.4 1 2 0 -0.0079 12 0 0 0 6.09E+06 4.30E+05 - - - 1.3133 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.20259.20259.2 0.00563 22-Sep K.FTVLLMPNGPMR[166.11].L sp|Q9UQ80|PA2G4_HUMAN 1 1384.7235 -1 52445 20259 2 1384.728542 693.369 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 9.75 3766.8 - 225157 - - - 3.6643 - 1.946 0.338 - 305.6 1 2 0 0.0051 12 0 0 0 0.00E+00 0.00E+00 - - - 3.2876 1 230117_WJC_METTL3_WT_vs_EV_F06.20261.20261.2 9.60E-07 13/28 K.ELVGPPLAETVFTPK[136.11].T sp|P49792|RBP2_HUMAN 1 1604.8905 2.05 52447 20261 2 1604.894942 803.4525 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3767.1 - 172278 - - - 2.7616 - 2.21 0.56 - 357.7 1 2 0 0.0044 15 0 0 0 2.52E+06 1.23E+06 - - - 5.1254 0.9947 230117_WJC_METTL3_WT_vs_EV_F06.20266.20266.2 0.0371 24-Dec R.LAALPNVYEVISK.S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1415.8024 2.38 52451 20266 2 1415.809024 708.9085 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3767.7 - 1.10E+06 - - - 4.6666 - 2.114 0.2 - 365.2 1 2 0 0.0066 13 0 0 0 2.03E+06 8.52E+05 - - - 2.4374 1 230117_WJC_METTL3_WT_vs_EV_F06.20268.20268.2 6.80E-09 16/36 R.YEGILYTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2100.0627 -1 52453 20268 2 2100.067034 1051.0386 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3767.9 - 859064 - - - 2.0795 - 3.392 0.622 - 554.3 1 2 0 0.0044 19 0 0 0 0.00E+00 0.00E+00 - - - 6.6366 1 230117_WJC_METTL3_WT_vs_EV_F06.20271.20271.2 3.38E-13 18/36 R.YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2108.0769 -1 52456 20271 2 2108.080873 1055.0457 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3768.3 - 702649 - - - 1.9003 - 3.607 0.698 - 855.8 1 2 0 0.004 19 0 0 0 0.00E+00 0.00E+00 - - - 7.3492 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.20272.20272.2 0.000885 18-Dec K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.69 52457 20272 2 1168.7125 585.3606 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3768.5 - 536477 - - - 4.9414 - 2.35 0.385 - 417.8 1 2 0 0.0058 10 0 0 0 9.17E+08 5.43E+08 - - - 4.2677 0.9942 230117_WJC_METTL3_WT_vs_EV_F06.20273.20273.2 0.0151 13/24 R.LAALPNVYEVISK[136.11].S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1423.8166 2.92 52458 20273 2 1423.825669 712.9156 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3768.6 - 497841 - - - 6.3576 - 2.298 0.367 - 422.6 1 2 0 0.0091 13 0 0 0 4.06E+06 1.39E+06 - - - 3.8843 1 230117_WJC_METTL3_WT_vs_EV_F06.20274.20274.2 0.000123 18-Dec R.GLAVFISDIR[166.11].N "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|M0R2D9|M0R2D9_HUMAN,tr|E9PR62|E9PR62_HUMAN" 4 1099.6265 0.71 52459 20274 2 1099.631292 550.8205 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 5.84 3768.7 - 467290 - - - 4.3442 - 2.449 0.465 - 758.6 1 2 0 0.0048 10 0 0 0 2.49E+06 3.53E+06 - - - 4.9741 0.9998 230117_WJC_METTL3_WT_vs_EV_F06.20275.20275.3 0.00228 14/72 R.YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2108.0769 -1 52460 20275 3 2108.08493 703.6996 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3768.9 - 407995 - - - 3.8248 - 2.92 0.451 - 262.7 1 2 0 0.0081 19 0 0 0 0.00E+00 0.00E+00 - - - 6.1986 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20279.20279.2 2.81E-05 22-Oct R.DLAQDEAVWLER.G "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1443.6994 -1 52464 20279 2 1443.699657 722.857 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 3.92 3769.4 - 310183 - - - 0.1725 - 1.861 0.407 - 235.8 1 2 0 0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 3.6813 1 230117_WJC_METTL3_WT_vs_EV_F06.20282.20282.2 2.19E-05 22-Dec R.DLAQDEAVWLER[166.11].G "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1453.7077 0.71 52467 20282 2 1453.713681 727.8611 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 3.92 3769.8 - 267989 - - - 4.1294 - 2.528 0.537 - 511 1 2 0 0.006 12 0 0 0 7.09E+05 1.00E+06 - - - 5.4456 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.20283.20283.2 0.000253 20-Sep K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 999 52468 20283 2 1184.716056 593.3637 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3769.9 - 261810 - - - 2.6867 - 1.632 0.444 - 130.8 1 2 0 0.0032 11 0 0 0 2.47E+06 0.00E+00 - - - 3.6444 0.999 230117_WJC_METTL3_WT_vs_EV_F06.20285.20285.2 9.03E-05 14-Aug R.GFC[160.03]FITFK[136.11].E "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1026.5088 0.85 52469 20285 2 1026.512809 514.2617 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.22 3770.1 - 8.49E+06 - - - 3.8821 - 1.52 0.514 - 239.4 1 2 0 0.004 8 0 0 0 4.21E+07 4.95E+07 - - - 4.099 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20287.20287.2 0.00757 13/18 K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.69 52471 20287 2 1176.722958 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3770.3 - 2.90E+06 - - - 1.7277 - 2.343 0.334 - 489.8 1 2 0 0.002 10 0 0 0 9.17E+08 5.43E+08 - - - 3.8839 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20292.20292.2 0.00155 14-Oct K.QFLPFLQR[166.11].A "sp|Q7KZF4|SND1_HUMAN,tr|H7C597|H7C597_HUMAN" 2 1057.5948 2.27 52476 20292 2 1057.597724 529.8047 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 9.75 3770.9 - 210652 - - - 2.7449 - 1.987 0.372 - 366.6 1 2 0 0.0029 8 0 0 0 8.49E+06 3.74E+06 - - - 3.8585 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20293.20293.2 2.23E-05 18-Aug K.NGFLLDGFPR.T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1134.5822 1.21 52477 20293 2 1134.584028 568.2984 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3771 - 208970 - - - 1.6165 - 1.743 0.415 - 248.9 1 2 0 0.0018 10 0 0 0 3.78E+06 3.12E+06 - - - 3.6565 0.897 230117_WJC_METTL3_WT_vs_EV_F06.20295.20295.2 3.53 12-Jun R.YMDLLWR.Y "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 995.4899 0.4 52479 20295 2 995.492364 498.7522 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 5.84 3771.3 - 148025 - - - 2.5023 - 0.87 0.071 - 72.1 1 2 0 0.0025 7 0 0 0 8.26E+05 2.09E+06 - - - -0.8766 1 230117_WJC_METTL3_WT_vs_EV_F06.20296.20296.2 0.00359 18-Aug K.NGFLLDGFPR[166.11].T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1144.5905 1.22 52480 20296 2 1144.594101 573.3025 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3771.4 - 123562 - - - 3.1776 - 1.883 0.519 - 248.6 1 2 0 0.0036 10 0 0 0 3.81E+06 3.12E+06 - - - 4.6397 0.9596 230117_WJC_METTL3_WT_vs_EV_F06.20297.20297.2 0.00053 18-Sep N.FAPEFELLAR.M "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1191.6288 3.31 52481 20297 2 1191.631563 596.8217 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 4.53 3771.5 - 105261 - - - 2.3111 - 1.761 0.387 - 224.8 1 1 0 0.0028 10 0 0 0 1.10E+06 3.33E+05 - - - 3.4781 1 230117_WJC_METTL3_WT_vs_EV_F06.20304.20304.2 3.62E-07 15/26 K.GLIGNLYLNDSPLK[136.11].N sp|Q8IW92|GLBL2_HUMAN 1 1523.8439 0.41 52488 20304 2 1523.848557 762.9292 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 5.83 3772.4 - 33256.7 - - - 3.06 - 3.035 0.51 - 1104.4 1 2 0 0.0047 14 0 0 0 3.08E+05 7.53E+05 - - - 5.5924 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20308.20308.2 1.02E-05 18-Nov R.TLVEDLFADK.H "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1149.5918 1.1 52491 20308 2 1149.594969 575.8032 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.03 3772.9 - 1.34E+06 - - - 2.7958 - 2.134 0.456 - 282.7 1 2 0 0.0032 10 0 0 0 4.34E+06 3.93E+06 - - - 4.5238 1 230117_WJC_METTL3_WT_vs_EV_F06.20309.20309.2 6.38E-06 13/22 R.GNSIIMLEALER.V "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1344.7071 -1 52492 20309 2 1344.707095 673.3608 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3772.9 - 1.25E+06 - - - -0.0305 - 2.654 0.515 - 692.6 1 2 0 0 12 0 0 0 0.00E+00 0.00E+00 - - - 5.413 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.20310.20310.2 0.00142 22-Nov R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 52493 20310 2 1603.760301 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3773.1 - 912822 - - - -2.269 - 1.738 0.493 - 316.8 1 2 0 -0.0036 12 0 0 0 1.08E+09 0.00E+00 - - - 4.1355 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.20311.20311.2 0.375 20-Oct R.LEYC[160.03]EALAMLR.E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1367.6577 -1 52494 20311 2 1367.658944 684.8361 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3773.2 - 903364 - - - 0.8781 - 2.131 0.243 - 366.1 1 2 0 0.0012 11 0 0 0 0.00E+00 0.00E+00 - - - 2.8822 0.9937 230117_WJC_METTL3_WT_vs_EV_F06.20312.20312.2 0.0687 14-Sep R.YLIYDIIK.F sp|O60942|MCE1_HUMAN 1 1039.5954 -1 52495 20312 2 1039.593338 520.805 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 5.83 3773.3 - 748708 - - - -1.9681 - 1.491 0.259 - 238.4 1 2 0 -0.002 8 0 0 0 0.00E+00 0.00E+00 - - - 2.158 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.20313.20313.3 0.0101 Nov-36 K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.75 52496 20313 3 1168.706682 390.5762 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3773.4 - 744088 - - - -0.0368 - 2.229 0.405 - 152.4 1 2 0 0 10 0 0 0 3.09E+06 1.77E+06 - - - 5.3962 1 230117_WJC_METTL3_WT_vs_EV_F06.20314.20314.2 2.56E-05 22-Dec R.GNSIIMLEALER[166.11].V "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1354.7154 -1 52497 20314 2 1354.713463 678.365 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3773.5 - 724683 - - - -1.4342 - 2.818 0.49 - 662.8 1 2 0 -0.0019 12 0 0 0 0.00E+00 0.00E+00 - - - 5.3855 0.997 230117_WJC_METTL3_WT_vs_EV_F06.20317.20317.3 0.021 Sep-36 K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.75 52500 20317 3 1176.718097 393.2476 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3773.8 - 375422 - - - -2.4033 - 1.935 0.297 - 82.9 1 2 0 -0.0028 10 0 0 0 3.09E+06 1.77E+06 - - - 3.7783 1 230117_WJC_METTL3_WT_vs_EV_F06.20319.20319.2 2.70E-06 14/26 K.LLAESVTEVEIFGK[136.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1541.8432 -1 52502 20319 2 1541.84442 771.9289 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 3774.1 - 240873 - - - 0.7744 - 2.949 0.584 - 591.5 1 2 0 0.0012 14 0 0 0 0.00E+00 0.00E+00 - - - 6.0679 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20320.20320.2 1.13E-05 22-Oct R.EAAQALLLAELR.R "sp|Q9Y4E6|WDR7_HUMAN,tr|A2RRE0|A2RRE0_HUMAN" 2 1296.7402 -1 52503 20320 2 1296.741455 649.3774 WD repeat-containing protein 7 OS=Homo sapiens OX=9606 GN=WDR7 PE=1 SV=2 4.53 3774.2 - 183528 - - - 1.0056 - 2.197 0.4 - 344.6 1 2 0 0.0013 12 0 0 0 0.00E+00 0.00E+00 - - - 4.066 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.20322.20322.2 4.80E-05 22-Oct R.LLVFGGMVEYGK.Y "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 1311.6897 1.99 52504 20322 2 1311.695162 656.8521 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 6 3774.6 - 378140 - - - 4.1679 - 1.774 0.459 - 300 1 2 0 0.0055 12 0 0 0 1.55E+06 7.79E+05 - - - 3.9377 1 230117_WJC_METTL3_WT_vs_EV_F06.20324.20324.3 3.92E-10 15/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 52505 20324 3 1603.762718 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3774.8 - 1.49E+06 - - - -0.762 - 2.543 0.649 - 335.3 1 2 0 -0.0012 12 0 0 0 1.20E+08 0.00E+00 - - - 8.3625 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20325.20325.2 0.0546 18-Aug R.VDILDPALLR.S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1123.6601 1.98 52506 20325 2 1123.660892 562.8373 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3774.9 - 401787 - - - 0.6959 - 1.904 0.411 - 205.6 1 2 0 0.0008 10 0 0 0 4.98E+07 2.52E+07 - - - 3.8739 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.20328.20328.2 0.000614 16-Jun R.FLYIWPNAR[166.11].L "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HKH3|A0A804HKH3_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 11 1188.6319 2.02 52509 20328 2 1188.633285 595.3232 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 8.75 3775 - 403713 - - - 1.1366 - 1.45 0.331 - 111.6 1 2 0 0.0014 9 0 0 0 5.52E+06 2.73E+06 - - - 2.5603 1 230117_WJC_METTL3_WT_vs_EV_F06.20330.20330.2 1.79E-06 16/24 R.LPSDVVTGYLALR.K "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1402.782 -1 52511 20330 2 1402.776081 702.3983 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 5.84 3775.2 - 0 - - - -4.2309 - 2.707 0.502 - 1158.8 1 2 0 -0.0059 13 0 0 0 0.00E+00 0.00E+00 - - - 5.3028 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20331.20331.2 0.0117 14-Sep R.FDILC[160.03]VVR.D "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1020.5426 0.78 52512 20331 2 1020.543031 511.2786 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 5.83 3775.2 - 166604 - - - 0.3861 - 1.94 0.344 - 332.8 1 2 0 0.0004 8 0 0 0 2.75E+06 3.54E+06 - - - 3.5803 0.972 230117_WJC_METTL3_WT_vs_EV_F06.20333.20333.2 0.467 18-Jun K.DFLLQQTMLR[166.11].V sp|Q04760|LGUL_HUMAN 1 1273.6728 1 52514 20333 2 1273.668443 637.8437 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 5.84 3775.3 - 174429 - - - -3.431 - 1.311 0.245 - 142.7 1 2 0 -0.0044 10 0 0 0 4.44E+06 4.44E+06 - - - 1.6051 1 230117_WJC_METTL3_WT_vs_EV_F06.20334.20334.2 0.00109 15/24 R.LAAVALINAAIQK[136.11].G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1302.8115 -1 52515 20334 2 1302.809127 652.413 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3775.5 - 0 - - - -1.8 - 2.823 0.394 - 827.5 1 2 0 -0.0023 13 0 0 0 0.00E+00 0.00E+00 - - - 4.6139 1 230117_WJC_METTL3_WT_vs_EV_F06.20335.20335.2 7.18E-05 20-Sep R.LEYC[160.03]EALAMLR[166.11].E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1377.666 -1 52516 20335 2 1377.661875 689.8403 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3775.6 - 0 - - - -3.0036 - 2.161 0.477 - 349.7 1 2 0 -0.0041 11 0 0 0 0.00E+00 0.00E+00 - - - 4.6474 1 230117_WJC_METTL3_WT_vs_EV_F06.20338.20338.2 5.48E-06 22-Oct R.GYELLFQPEVVR.L "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A804HJM1|A0A804HJM1_HUMAN,tr|A0A804HK15|A0A804HK15_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN,tr|A0A804HIL4|A0A804HIL4_HUMAN" 8 1448.7664 -1 52519 20338 2 1448.765748 725.3905 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 4.53 3776 - 0 - - - -0.4266 - 2.189 0.518 - 316.1 1 2 0 -0.0006 12 0 0 0 0.00E+00 0.00E+00 - - - 4.9281 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.20341.20341.3 0.000228 Dec-48 R.LAAVALINAAIQK.G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1294.7973 -1 52522 20341 3 1294.79661 432.6064 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3776.4 - 141028 - - - -0.5113 - 2.384 0.435 - 238.5 1 2 0 -0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 5.7452 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.20347.20347.2 0.389 18-Aug R.VDILDPALLR[166.11].S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1133.6684 1.98 52527 20347 2 1133.669681 567.8415 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3777 - 1.43E+07 - - - 1.1476 - 1.911 0.226 - 186.3 1 2 0 0.0013 10 0 0 0 4.98E+07 2.52E+07 - - - 2.5176 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20354.20354.2 0.139 20-Dec R.VYGALMWSLGK.V "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|C9JDQ8|C9JDQ8_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 7 1223.6373 -1 52534 20354 2 1223.639615 612.8259 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 8.56 3777.4 - 2.20E+06 - - - 1.9197 - 2.05 0.428 - 402.1 1 2 0 0.0024 11 0 0 0 0.00E+00 0.00E+00 - - - 4.1434 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20356.20356.2 0.0299 14/24 R.LAAVALINAAIQK.G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1294.7973 0.98 52536 20356 2 1294.797249 648.4059 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3777.6 - 1.96E+06 - - - -0.0178 - 2.878 0.347 - 696.8 1 2 0 0 13 0 0 0 3.06E+06 3.12E+06 - - - 4.317 1 230117_WJC_METTL3_WT_vs_EV_F06.20358.20358.2 4.13E-06 16/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 52538 20358 2 1343.609789 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3777.9 - 1.89E+06 - - - -1.2452 - 2.895 0.526 - 1016.1 1 1 0 -0.0017 10 0 0 0 5.02E+06 0.00E+00 - - - 5.8926 1 230117_WJC_METTL3_WT_vs_EV_F06.20361.20361.2 0.0066 14/22 K.TVLLLADQMISR[166.11].L "sp|P48730|KC1D_HUMAN,sp|P49674|KC1E_HUMAN,tr|B0QY36|B0QY36_HUMAN,tr|B0QY34|B0QY34_HUMAN,tr|H7BYT1|H7BYT1_HUMAN,tr|J3QQI9|J3QQI9_HUMAN,tr|A0A669KBC0|A0A669KBC0_HUMAN,tr|H0Y645|H0Y645_HUMAN,tr|B0QY35|B0QY35_HUMAN,tr|H0Y2N6|H0Y2N6_HUMAN" 10 1368.7674 -1 52541 20361 2 1368.76761 685.391 Casein kinase I isoform delta OS=Homo sapiens OX=9606 GN=CSNK1D PE=1 SV=2 5.5 3778.3 - 1.28E+06 - - - 0.1227 - 2.752 0.431 - 834.8 1 2 0 0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 4.8879 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.20362.20362.2 0.0083 18-Aug K.LVFPQDLLEK.G "sp|Q8TCT9|HM13_HUMAN,tr|A0A3B3IT72|A0A3B3IT72_HUMAN,tr|A0A0S2Z6F0|A0A0S2Z6F0_HUMAN,tr|A0A3B3IUB5|A0A3B3IUB5_HUMAN,tr|A0A075B6F6|A0A075B6F6_HUMAN" 5 1200.6754 -1 52542 20362 2 1200.676477 601.345 Minor histocompatibility antigen H13 OS=Homo sapiens OX=9606 GN=HM13 PE=1 SV=1 4.37 3778.4 - 1.25E+06 - - - 0.8762 - 1.684 0.29 - 161.5 1 2 0 0.0011 10 0 0 0 0.00E+00 0.00E+00 - - - 2.6374 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.20371.20371.2 0.0722 12-Jul K.LWDLYLR.T "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 977.5335 1.97 52550 20371 2 977.535129 489.774 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.84 3779.4 - 695471 - - - 1.7155 - 1.513 0.167 - 221.8 1 2 0 0.0017 7 0 0 0 6.06E+06 3.08E+06 - - - 1.586 1 230117_WJC_METTL3_WT_vs_EV_F06.20374.20374.2 3.24E-05 13/22 K.GAVEALAAALAH.L sp|Q9NR30|DDX21_HUMAN 1 1092.5928 - 52553 20374 2 1092.586469 547.3037 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.24 3779.7 - 396665 - - - -5.756 - 2.747 0.491 - 417.5 1 1 0 -0.0063 12 0 0 0 - - - - - 5.3244 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20375.20375.2 0.00316 20-Nov K.SIDPALSMLIK[136.11].S sp|Q9H501|ESF1_HUMAN 1 1194.6773 1.04 52554 20375 2 1194.679014 598.3459 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 5.55 3779.7 - 367649 - - - 1.3962 - 1.994 0.424 - 307.7 1 2 0 0.0017 11 0 0 0 2.65E+06 2.55E+06 - - - 4.0391 0.9966 230117_WJC_METTL3_WT_vs_EV_F06.20376.20376.2 0.0378 14-Aug K.QELLELFK[136.11].E "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1026.5841 0.67 52555 20376 2 1026.58256 514.2993 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 4.53 3779.8 - 329665 - - - -1.4982 - 1.614 0.271 - 196.6 1 2 0 -0.0015 8 0 0 0 6.35E+06 9.44E+06 - - - 2.4859 1 230117_WJC_METTL3_WT_vs_EV_F06.20379.20379.2 0.00261 14/22 K.TVLLLADQMISR.L "sp|P48730|KC1D_HUMAN,sp|P49674|KC1E_HUMAN,tr|B0QY36|B0QY36_HUMAN,tr|B0QY34|B0QY34_HUMAN,tr|H7BYT1|H7BYT1_HUMAN,tr|J3QQI9|J3QQI9_HUMAN,tr|A0A669KBC0|A0A669KBC0_HUMAN,tr|H0Y645|H0Y645_HUMAN,tr|B0QY35|B0QY35_HUMAN,tr|H0Y2N6|H0Y2N6_HUMAN" 10 1358.7592 1.48 52558 20379 2 1358.764748 680.3869 Casein kinase I isoform delta OS=Homo sapiens OX=9606 GN=CSNK1D PE=1 SV=2 5.5 3780.1 - 299175 - - - 4.1037 - 2.753 0.444 - 860.4 1 2 0 0.0056 12 0 0 0 3.29E+06 2.23E+06 - - - 4.9832 0.9917 230117_WJC_METTL3_WT_vs_EV_F06.20386.20386.2 2.23 14-Jul R.SGLLGELR.N "sp|O60336|MABP1_HUMAN,tr|D6RHX7|D6RHX7_HUMAN" 2 843.4814 11.9 52563 20386 2 843.482131 422.748 Mitogen-activated protein kinase-binding protein 1 OS=Homo sapiens OX=9606 GN=MAPKBP1 PE=1 SV=4 5.72 3781 - 2.21E+06 - - - 0.8465 - 1.377 0.086 - 166.1 1 2 0 0.0007 8 0 0 0 8.60E+06 7.23E+05 - - - 0.6408 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20388.20388.2 0.00524 16-Sep K.ELALSALLK[136.11].F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 964.6048 1.06 52565 20388 2 964.606348 483.3097 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3781.3 - 2.08E+06 - - - 1.5706 - 1.875 0.311 - 278.1 1 2 0 0.0015 9 0 0 0 1.39E+07 1.31E+07 - - - 3.1562 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20389.20389.2 0.00371 14-Sep K.QELLELFK.E "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1018.5699 0.67 52566 20389 2 1018.572064 510.2922 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 4.53 3781.4 - 1.73E+06 - - - 2.1265 - 1.827 0.333 - 296.5 1 2 0 0.0022 8 0 0 0 6.35E+06 9.44E+06 - - - 3.3175 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20390.20390.2 0.0035 16-Oct K.ELALSALLK.F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 956.5906 1.06 52567 20390 2 956.591942 479.3026 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3781.5 - 1.67E+06 - - - 1.3684 - 2.112 0.315 - 313.2 1 2 0 0.0013 9 0 0 0 1.39E+07 1.31E+07 - - - 3.5301 0.991 230117_WJC_METTL3_WT_vs_EV_F06.20393.20393.2 3.09 12-Sep K.LDDLFLK.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 862.48 1.51 52570 20393 2 862.480484 432.2473 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3781.9 - 1.12E+06 - - - 0.538 - 1.653 0.002 - 237.2 1 2 0 0.0005 7 0 0 0 4.18E+06 2.77E+06 - - - 0.6481 1 230117_WJC_METTL3_WT_vs_EV_F06.20394.20394.2 4.17E-07 13/22 R.LLTFMGMAVENK[136.11].E "sp|Q7L2H7|EIF3M_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 2 1360.6974 0.85 52571 20394 2 1360.700899 681.356 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6 3782 - 1.09E+06 - - - 2.5494 - 2.583 0.598 - 582 1 2 0 0.0035 12 0 0 0 4.12E+06 4.86E+06 - - - 5.9536 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20396.20396.2 0.0003 16-Oct K.LISLFQAMK.K "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1049.5943 2.65 52573 20396 2 1049.595868 525.8044 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.75 3782.3 - 1.03E+06 - - - 1.4577 - 1.931 0.399 - 230 1 2 0 0.0015 9 0 0 0 3.08E+06 1.16E+06 - - - 3.8913 0.9845 230117_WJC_METTL3_WT_vs_EV_F06.20398.20398.2 1.09 12-Jun K.LDDLFLK[136.11].R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 870.4942 1.51 52575 20398 2 870.495409 436.2544 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3782.5 - 980428 - - - 1.3659 - 1.528 0 - 104.4 3 2 0 0.0012 7 0 0 0 4.18E+06 2.77E+06 - - - 0.1708 0.997 230117_WJC_METTL3_WT_vs_EV_F06.20399.20399.2 0.221 12-Jul K.LWDLYLR[166.11].T "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 987.5417 1.97 52576 20399 2 987.543523 494.7781 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.84 3782.7 - 941785 - - - 1.8237 - 1.54 0.137 - 153.8 1 2 0 0.0018 7 0 0 0 6.06E+06 3.08E+06 - - - 1.4204 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.20400.20400.2 0.0169 20-Aug K.SIDPALSMLIK.S sp|Q9H501|ESF1_HUMAN 1 1186.6631 1.04 52577 20400 2 1186.665451 594.3388 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 5.55 3782.8 - 764580 - - - 1.9424 - 1.505 0.26 - 142.2 1 2 0 0.0023 11 0 0 0 2.65E+06 2.55E+06 - - - 2.0665 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.20401.20401.2 0.00647 20-Sep K.IGPITPLEFYR.E "sp|Q13867|BLMH_HUMAN,tr|K7ESE8|K7ESE8_HUMAN,tr|J3KSD8|J3KSD8_HUMAN,tr|K7ES02|K7ES02_HUMAN" 4 1304.7129 5.84 52578 20401 2 1304.717616 653.3637 Bleomycin hydrolase OS=Homo sapiens OX=9606 GN=BLMH PE=1 SV=1 6 3782.9 - 658632 - - - 3.6353 - 1.873 0.285 - 210.7 1 2 0 0.0047 11 0 0 0 2.58E+07 4.42E+06 - - - 2.8422 1 230117_WJC_METTL3_WT_vs_EV_F06.20402.20402.2 2.43E-07 26-Nov R.IGPYQPNVPVGIDY.V "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1530.7718 - 52579 20402 2 1530.77384 766.3932 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 3.8 3783.1 - 601264 - - - 1.3033 - 2.393 0.571 - 307.1 1 1 0 0.002 14 0 0 0 - - - - - 5.4474 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.20403.20403.2 0.000209 16-Sep R.YEGFFGLYR[166.11].G "sp|O75746|CMC1_HUMAN,sp|Q9UJS0|CMC2_HUMAN" 2 1160.553 1.41 52580 20403 2 1160.55317 581.2838 Calcium-binding mitochondrial carrier protein Aralar1 OS=Homo sapiens OX=9606 GN=SLC25A12 PE=1 SV=2 6 3783.2 - 587566 - - - 0.1336 - 1.88 0.195 - 247.6 1 2 0 0.0002 9 0 0 0 2.89E+06 2.05E+06 - - - 2.3075 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20405.20405.2 0.000141 22-Sep K.VESLQEEIAFLK[136.11].K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1412.7642 1.52 52582 20405 2 1412.767834 707.3894 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3783.4 - 543575 - - - 2.539 - 2.127 0.446 - 239 1 2 0 0.0036 12 0 0 0 5.16E+06 3.40E+06 - - - 4.3198 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.20408.20408.2 0.00328 18-Jul K.LVFPQDLLEK[136.11].G "sp|Q8TCT9|HM13_HUMAN,tr|A0A3B3IT72|A0A3B3IT72_HUMAN,tr|A0A0S2Z6F0|A0A0S2Z6F0_HUMAN,tr|A0A3B3IUB5|A0A3B3IUB5_HUMAN,tr|A0A075B6F6|A0A075B6F6_HUMAN" 5 1208.6896 1.48 52584 20408 2 1208.692051 605.3521 Minor histocompatibility antigen H13 OS=Homo sapiens OX=9606 GN=HM13 PE=1 SV=1 4.37 3783.9 - 644945 - - - 2.0071 - 1.528 0.354 - 125.1 1 2 0 0.0024 10 0 0 0 7.69E+06 5.19E+06 - - - 2.8383 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.20409.20409.2 0.166 16-Oct K.EIIDLVLDR.L "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 9 1084.6128 3.11 52585 20409 2 1084.612301 543.3137 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.03 3784 - 7.67E+06 - - - -0.4831 - 1.845 0.232 - 428.1 1 2 0 -0.0005 9 0 0 0 2.14E+08 6.88E+07 - - - 2.5263 0.9932 230117_WJC_METTL3_WT_vs_EV_F06.20411.20411.2 0.00931 12-Jul K.VFFDLMR.E "sp|P11234|RALB_HUMAN,sp|P11233|RALA_HUMAN" 2 926.4684 1.4 52587 20411 2 926.467758 464.2415 Ras-related protein Ral-B OS=Homo sapiens OX=9606 GN=RALB PE=1 SV=1 5.81 3784.2 - 1.39E+06 - - - -0.7027 - 1.253 0.218 - 157.4 1 2 0 -0.0007 7 0 0 0 5.43E+06 3.88E+06 - - - 1.3656 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20412.20412.2 0.0212 18-Oct K.AEVLWLMGAK[136.11].S sp|O94906|PRP6_HUMAN 1 1124.6144 0.68 52588 20412 2 1124.617107 563.3145 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.05 3784.4 - 1.31E+06 - - - 2.4497 - 1.909 0.424 - 361.8 1 2 0 0.0028 10 0 0 0 6.62E+06 9.66E+06 - - - 3.9766 1 230117_WJC_METTL3_WT_vs_EV_F06.20417.20417.2 4.26E-05 13/22 K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.8 52593 20417 2 1317.70953 659.862 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3785 - 838527 - - - 0.1176 - 2.542 0.583 - 334.1 1 2 0 0.0002 12 0 0 0 1.73E+08 2.16E+08 - - - 5.8017 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20420.20420.2 0.000712 16-Sep K.DLFQVAFNR.V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN" 15 1108.5665 1.92 52596 20420 2 1108.566063 555.2905 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.84 3785.4 - 714767 - - - -0.433 - 1.673 0.499 - 272.4 1 2 0 -0.0005 9 0 0 0 2.04E+06 1.06E+06 - - - 4.2153 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.20421.20421.2 0.0701 22-Oct K.VILLDPSIIEAK.M sp|Q07617|SPAG1_HUMAN 1 1309.7857 -1 52597 20421 2 1309.784811 655.9001 Sperm-associated antigen 1 OS=Homo sapiens OX=9606 GN=SPAG1 PE=1 SV=3 4.37 3785.5 - 701305 - - - -0.6818 - 1.34 0.347 - 125.7 1 2 0 -0.0009 12 0 0 0 0.00E+00 0.00E+00 - - - 2.3737 1 230117_WJC_METTL3_WT_vs_EV_F06.20422.20422.2 2.50E-05 18-Sep -.MFLYNLTLQR.A "sp|Q15393|SF3B3_HUMAN,tr|H3BMB0|H3BMB0_HUMAN,tr|I3L4G7|I3L4G7_HUMAN" 3 1297.6853 0.09 52598 20422 2 1297.68579 649.8499 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.5 3785.6 - 497363 - - - 0.3945 - 2.061 0.504 - 309.6 1 2 0 0.0005 10 0 0 0 1.13E+07 1.32E+08 - - - 4.782 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.20424.20424.2 0.000765 20-Oct R.GVTYLFPIQVK.T sp|Q9BQ39|DDX50_HUMAN 1 1263.7227 0.96 52600 20424 2 1263.727755 632.8686 ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1 8.59 3785.9 - 413273 - - - 3.9922 - 2.016 0.395 - 449.4 1 2 0 0.005 11 0 0 0 1.74E+06 1.81E+06 - - - 3.8536 1 230117_WJC_METTL3_WT_vs_EV_F06.20428.20428.2 3.30E-06 22-Nov R.LLTFMGMAVENK.E "sp|Q7L2H7|EIF3M_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 2 1352.6832 0.8 52603 20428 2 1352.681717 677.3489 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6 3786.4 - 433172 - - - -1.1185 - 2.518 0.575 - 418.2 1 2 0 -0.0015 12 0 0 0 3.83E+06 4.78E+06 - - - 5.7173 1 230117_WJC_METTL3_WT_vs_EV_F06.20429.20429.2 3.56E-06 20-Sep K.C[160.03]GPMVLDALIK.L "sp|P21912|SDHB_HUMAN,tr|A0A087WWT1|A0A087WWT1_HUMAN,tr|A0A087WXX8|A0A087WXX8_HUMAN" 3 1215.6356 -1 52604 20429 2 1215.636404 608.8251 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.83 3786.5 - 333700 - - - 0.7017 - 2.045 0.561 - 168 1 2 0 0.0009 11 0 0 0 0.00E+00 0.00E+00 - - - 5.1196 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20433.20433.2 0.00245 18-Aug K.AEVLWLMGAK.S sp|O94906|PRP6_HUMAN 1 1116.6002 0.68 52608 20433 2 1116.599976 559.3074 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.05 3786.7 - 1.53E+06 - - - -0.1576 - 1.925 0.403 - 249.5 1 2 0 -0.0002 10 0 0 0 6.27E+06 9.19E+06 - - - 3.8456 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.20435.20435.2 0.000924 14-Jul R.EIFNFVLK[136.11].A sp|P78527|PRKDC_HUMAN 1 1016.5786 1.2 52610 20435 2 1016.580315 509.2966 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6.1 3786.8 - 1.16E+06 - - - 1.6693 - 1.431 0.405 - 181.5 1 2 0 0.0017 8 0 0 0 8.93E+06 7.41E+06 - - - 3.1126 0.9075 230117_WJC_METTL3_WT_vs_EV_F06.20436.20436.2 0.0195 18-Jul R.WFTHASPTLF.N "sp|P23921|RIR1_HUMAN,tr|H0YCY7|H0YCY7_HUMAN" 2 1205.5869 - 52611 20436 2 1205.590472 603.8007 Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1 6.74 3787 - 710054 - - - 2.9255 - 1.586 0.326 - 86.6 1 1 0 0.0035 10 0 0 0 - - - - - 2.7351 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.20437.20437.2 0.171 14-Jun R.EVMLILIR[166.11].E sp|O75533|SF3B1_HUMAN 1 995.6077 0.48 52612 20437 2 995.608964 498.8111 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.1 3787.1 - 489281 - - - 1.2756 - 1.404 0.236 - 139.5 1 2 0 0.0013 8 0 0 0 1.68E+06 3.51E+06 - - - 1.8071 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20442.20442.2 0.00399 16-Aug K.EIIDLVLDR[166.11].L "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 9 1094.6211 3.11 52616 20442 2 1094.622997 548.3178 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.03 3787.7 - 1.58E+07 - - - 1.7376 - 1.79 0.445 - 312.3 1 2 0 0.0019 9 0 0 0 2.14E+08 6.88E+07 - - - 4.0116 0.999 230117_WJC_METTL3_WT_vs_EV_F06.20443.20443.2 0.00382 14-Jul R.EIFNFVLK.A sp|P78527|PRKDC_HUMAN 1 1008.5644 1.22 52617 20443 2 1008.564831 505.2895 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6.1 3787.8 - 1.37E+06 - - - 0.4095 - 1.344 0.359 - 181.5 1 2 0 0.0004 8 0 0 0 9.02E+06 7.41E+06 - - - 2.5841 1 230117_WJC_METTL3_WT_vs_EV_F06.20446.20446.2 3.08E-07 15/30 K.IITLEEGDIILTGTPK.G sp|Q6P587|FAHD1_HUMAN 1 1711.9608 1.96 52620 20446 2 1711.960498 856.9877 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3788 - 1.10E+06 - - - -0.1577 - 3.15 0.601 - 660.6 1 2 0 -0.0003 16 0 0 0 2.90E+06 1.48E+06 - - - 6.3008 1 230117_WJC_METTL3_WT_vs_EV_F06.20447.20447.3 1.68E-08 16/44 K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.55 52621 20447 3 1317.709538 440.2437 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3788.1 - 791851 - - - 0.1237 - 2.906 0.598 - 460.1 1 2 0 0.0002 12 0 0 0 3.71E+06 6.76E+06 - - - 8.164 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.20450.20450.2 0.00175 16-Aug K.LLYTFPGWK[136.11].V "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1131.6208 1.5 52624 20450 2 1131.620535 566.8177 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 8.59 3788.5 - 670732 - - - -0.2492 - 1.855 0.356 - 145.6 1 2 0 -0.0003 9 0 0 0 8.72E+06 5.81E+06 - - - 3.4579 1 230117_WJC_METTL3_WT_vs_EV_F06.20452.20452.3 1.04E-06 Dec-44 K.TVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1309.6952 0.55 52626 20452 3 1309.694929 437.5723 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3788.8 - 394933 - - - -0.1878 - 2.577 0.564 - 255 1 2 0 -0.0002 12 0 0 0 3.71E+06 6.74E+06 - - - 7.4519 1 230117_WJC_METTL3_WT_vs_EV_F06.20456.20456.2 0.000103 13/22 K.TVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1309.6952 0.79 52628 20456 2 1309.691807 655.8549 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3789.4 - 281264 - - - -2.5716 - 2.64 0.53 - 347 1 2 0 -0.0034 12 0 0 0 1.70E+08 2.16E+08 - - - 5.5088 1 230117_WJC_METTL3_WT_vs_EV_F06.20458.20458.2 4.20E-08 13/24 K.LFQEDDEIPLYLK[136.11].G "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6RGV5|D6RGV5_HUMAN" 4 1629.8381 1.03 52630 20458 2 1629.828221 815.9263 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 3.92 3789.5 - 84288.7 - - - -6.0859 - 2.572 0.634 - 453.3 1 2 0 -0.0099 13 0 0 0 7.04E+06 6.82E+06 - - - 6.1452 0.9865 230117_WJC_METTL3_WT_vs_EV_F06.20459.20459.2 0.0298 14-Aug R.LLDFLNVK[136.11].N sp|Q8NDZ4|DIK2A_HUMAN 1 968.5786 0.81 52631 20459 2 968.575011 485.2966 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 5.84 3789.6 - 0 - - - -3.724 - 1.333 0.351 - 133.6 1 2 0 -0.0036 8 0 0 0 3.33E+06 4.12E+06 - - - 2.4992 0.9901 230117_WJC_METTL3_WT_vs_EV_F06.20460.20460.2 0.005 14-Sep R.LLDFLNVK.N sp|Q8NDZ4|DIK2A_HUMAN 1 960.5644 0.81 52632 20460 2 960.56098 481.2895 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 5.84 3789.7 - 53520.4 - - - -3.5791 - 1.566 0.32 - 184.8 1 2 0 -0.0034 8 0 0 0 3.33E+06 4.12E+06 - - - 2.7562 0.9947 230117_WJC_METTL3_WT_vs_EV_F06.20464.20464.2 0.0129 14-Jul R.EVMLILIR.E sp|O75533|SF3B1_HUMAN 1 985.5994 0.47 52636 20464 2 985.59703 493.807 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.1 3790.2 - 0 - - - -2.429 - 1.546 0.309 - 233.3 1 2 0 -0.0024 8 0 0 0 1.68E+06 3.60E+06 - - - 2.6365 1 230117_WJC_METTL3_WT_vs_EV_F06.20466.20466.2 5.68E-07 15/30 K.IITLEEGDIILTGTPK[136.11].G sp|Q6P587|FAHD1_HUMAN 1 1719.975 -1 52638 20466 2 1719.968892 860.9948 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3790.4 - 64022.7 - - - -3.5326 - 2.945 0.495 - 587.6 1 2 0 -0.0061 16 0 0 0 0.00E+00 0.00E+00 - - - 5.3507 0.8859 230117_WJC_METTL3_WT_vs_EV_F06.20469.20469.2 0.0207 22-Oct R.VALDMTTLTIMR[166.11].Y "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 4 1373.7286 0.89 52641 20469 2 1374.735723 687.8716 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.81 3790.8 - 0 - - - 733.1215 - 1.951 0.272 - 232.7 1 2 0 1.0071 12 0 0 0 7.60E+06 8.50E+06 - - - 2.4923 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.20470.20470.2 1.08E-05 18-Sep K.FTMVQVWPVR.Q "sp|P38606|VATA_HUMAN,tr|C9JA17|C9JA17_HUMAN,tr|C9JVW8|C9JVW8_HUMAN" 3 1261.6641 0.89 52642 20470 2 1261.662361 631.8394 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 9.75 3790.9 - 0 - - - -1.4172 - 1.848 0.331 - 340.5 1 2 0 -0.0018 10 0 0 0 5.26E+06 5.87E+06 - - - 3.1994 1 230117_WJC_METTL3_WT_vs_EV_F06.20471.20471.2 1.03E-05 22-Dec R.IRDLLYEQYAIV.- sp|Q9P2I0|CPSF2_HUMAN 1 1494.8082 1.46 52643 20471 2 1494.807753 748.4114 Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2 4.37 3791 - 0 - - - -0.3191 - 2.192 0.476 - 373.8 1 2 1 -0.0005 12 0 0 0 1.99E+06 1.37E+06 - - - 4.6216 1 230117_WJC_METTL3_WT_vs_EV_F06.20472.20472.2 7.28E-07 22-Nov R.VALDMTTLTIMR.Y "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 4 1363.7203 0.89 52644 20472 2 1363.714384 682.8674 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.81 3791.2 - 89952.8 - - - -4.3697 - 2.288 0.459 - 428.9 1 2 0 -0.006 12 0 0 0 7.60E+06 8.50E+06 - - - 4.6071 0.985 230117_WJC_METTL3_WT_vs_EV_F06.20473.20473.2 0.0085 24-Nov R.LELYAQATEALLK.T "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1461.8079 -1 52645 20473 2 1461.7998 731.9112 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 4.53 3791.3 - 0 - - - -5.5383 - 2.16 0.398 - 189.1 1 2 0 -0.0081 13 0 0 0 0.00E+00 0.00E+00 - - - 3.9546 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20482.20482.2 0.00209 22-Sep R.IIPYLSFGEVEK.M "sp|Q5T4S7|UBR4_HUMAN,tr|X6R960|X6R960_HUMAN" 2 1393.7493 2.19 52653 20482 2 1393.752494 697.8819 E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1 4.53 3792.4 - 410627 - - - 2.278 - 1.63 0.456 - 237.7 1 2 0 0.0032 12 0 0 0 4.23E+06 1.93E+06 - - - 3.6936 1 230117_WJC_METTL3_WT_vs_EV_F06.20483.20483.2 3.75E-10 17/26 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.63 52654 20483 2 1487.773578 744.8959 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3792.5 - 387218 - - - -2.4782 - 2.833 0.516 - 760.9 1 2 0 -0.0037 14 0 0 0 4.40E+07 2.71E+07 - - - 5.4642 1 230117_WJC_METTL3_WT_vs_EV_F06.20487.20487.2 1.29E-08 16/26 R.YSALFLGVAYGATR[166.11].Y sp|P56385|ATP5I_HUMAN 1 1497.7855 1.63 52658 20487 2 1497.783212 749.9 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3793.1 - 278684 - - - -1.551 - 2.849 0.649 - 786.9 1 2 0 -0.0023 14 0 0 0 4.40E+07 2.71E+07 - - - 6.4611 0.9928 230117_WJC_METTL3_WT_vs_EV_F06.20491.20491.2 0.137 20-Jun K.GVPTGFILPIR[166.11].D "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1178.7051 3.87 52660 20491 2 1178.701036 590.3598 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 3793.6 - 577451 - - - -3.447 - 1.585 0.375 - 137.2 1 2 0 -0.0041 11 0 0 0 9.31E+07 2.40E+07 - - - 3.0555 1 230117_WJC_METTL3_WT_vs_EV_F06.20496.20496.2 5.30E-05 14/30 R.LMNDMTAVALNYGIYK.Q sp|Q92598|HS105_HUMAN 1 1815.8899 48.53 52665 20496 2 1815.891749 908.9522 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.83 3794.2 - 179670 - - - 1.0028 - 2.893 0.627 - 411.5 1 2 0 0.0018 16 0 0 0 5.64E+06 1.16E+05 - - - 6.2831 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.20499.20499.3 0.000261 Nov-40 R.LHQLLALTLWK.E "sp|Q7L5D6|GET4_HUMAN,tr|C9JPA8|C9JPA8_HUMAN,tr|C9JHN8|C9JHN8_HUMAN,tr|C9JY46|C9JY46_HUMAN" 4 1334.8074 1.95 52668 20499 3 1334.809088 445.9431 Golgi to ER traffic protein 4 homolog OS=Homo sapiens OX=9606 GN=GET4 PE=1 SV=1 8.76 3794.6 - 493435 - - - 1.2324 - 1.918 0.474 - 144.6 1 2 0 0.0016 11 0 0 0 9.03E+05 4.63E+05 - - - 5.6744 0.9939 230117_WJC_METTL3_WT_vs_EV_F06.20500.20500.2 0.000497 Nov-34 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.87 52669 20500 2 1976.078675 989.0504 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3794.7 - 0 - - - -3.8333 - 1.753 0.44 - 173.1 1 2 0 -0.0076 18 0 0 0 4.83E+06 2.58E+06 - - - 3.6685 1 230117_WJC_METTL3_WT_vs_EV_F06.20507.20507.2 1.63E-07 28-Nov K.GVYPDLLATSGDYLR.V sp|P61962|DCAF7_HUMAN 1 1638.8253 1.93 52673 20507 2 1638.822148 820.4199 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3795.4 - 0 - - - -1.9459 - 2.37 0.637 - 320 1 2 0 -0.0032 15 0 0 0 9.51E+06 4.93E+06 - - - 5.8663 1 230117_WJC_METTL3_WT_vs_EV_F06.20508.20508.2 0.000336 18-Oct K.VLEAELLVLR[166.11].Q sp|P07196|NFL_HUMAN 1 1163.7153 0.39 52674 20508 2 1163.712975 582.8649 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.53 3795.4 - 0 - - - -2.0237 - 1.99 0.503 - 400.7 1 2 0 -0.0024 10 0 0 0 3.27E+06 8.38E+06 - - - 4.6762 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.20511.20511.2 0.00536 16-Jul K.DVMDALILK[136.11].M sp|Q8N1G4|LRC47_HUMAN 1 1024.5718 1.4 52677 20511 2 1024.570221 513.2932 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 4.21 3795.7 - 0 - - - -1.5587 - 1.378 0.385 - 125.3 1 2 0 -0.0016 9 0 0 0 5.58E+06 3.99E+06 - - - 2.8117 1 230117_WJC_METTL3_WT_vs_EV_F06.20512.20512.2 1.44E-07 28-Oct K.GVYPDLLATSGDYLR[166.11].V sp|P61962|DCAF7_HUMAN 1 1648.8336 1.91 52678 20512 2 1648.826788 825.4241 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3795.7 - 0 - - - -4.1357 - 2.02 0.567 - 200.5 1 2 0 -0.0068 15 0 0 0 9.51E+06 4.99E+06 - - - 4.9553 0.9908 230117_WJC_METTL3_WT_vs_EV_F06.20515.20515.2 0.000368 20-Sep K.AGFLAFTQLPK.F "sp|O75165|DJC13_HUMAN,tr|A0A3B3IRM0|A0A3B3IRM0_HUMAN" 2 1191.6652 1.11 52681 20515 2 1191.662173 596.8399 DnaJ homolog subfamily C member 13 OS=Homo sapiens OX=9606 GN=DNAJC13 PE=1 SV=5 8.8 3796 - 0 - - - -2.5359 - 1.644 0.237 - 160.5 1 2 0 -0.003 11 0 0 0 5.10E+06 4.58E+06 - - - 2.1354 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.20524.20524.2 0.0203 14-Aug K.AWGILTFK[136.11].G "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 942.5418 1.28 52688 20524 2 942.540936 472.2782 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 8.8 3797 - 3.50E+06 - - - -0.958 - 1.494 0.376 - 318.3 1 2 0 -0.0009 8 0 0 0 1.41E+08 1.10E+08 - - - 3.0286 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.20526.20526.2 0.0361 14-Aug R.VLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 881.6062 1.31 52690 20526 2 881.607952 441.8104 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3797.1 - 840009 - - - 1.9612 - 1.735 0.332 - 181.5 1 2 0 0.0017 8 0 0 0 4.92E+07 3.76E+07 - - - 3.1544 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.20527.20527.2 0.00125 16-Aug K.DVMDALILK.M sp|Q8N1G4|LRC47_HUMAN 1 1016.5576 1.41 52691 20527 2 1016.557119 509.2861 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 4.21 3797.2 - 641217 - - - -0.4909 - 1.531 0.421 - 167.4 1 2 0 -0.0005 9 0 0 0 5.62E+06 3.99E+06 - - - 3.3826 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.20528.20528.2 0.000669 16-Sep R.LVSYYYFLR[166.11].F sp|Q7LGA3|HS2ST_HUMAN 1 1232.6469 0.86 52692 20528 2 1232.646528 617.3307 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 8.5 3797.3 - 348231 - - - -0.3148 - 1.614 0.404 - 241.2 1 2 0 -0.0004 9 0 0 0 2.30E+07 2.68E+07 - - - 3.4098 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.20535.20535.2 0.000123 18-Jul K.LLPFLSNPYR.N sp|Q13625|ASPP2_HUMAN 1 1218.6761 4.3 52697 20535 2 1218.677011 610.3453 Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=9606 GN=TP53BP2 PE=1 SV=2 8.75 3798.2 - 0 - - - 0.7525 - 1.461 0.391 - 164.9 1 2 0 0.0009 10 0 0 0 6.61E+06 1.54E+06 - - - 2.9869 0.998 230117_WJC_METTL3_WT_vs_EV_F06.20540.20540.2 1.56 14-Sep R.VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 891.6145 1.31 52700 20540 2 891.613184 446.8145 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3798.8 - 3.34E+06 - - - -1.4681 - 1.867 0.295 - 361.3 1 2 0 -0.0013 8 0 0 0 4.92E+07 3.76E+07 - - - 3.1024 1 230117_WJC_METTL3_WT_vs_EV_F06.20542.20542.2 0.00754 20-Dec K.GIFNGFSVTLK.E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1181.6445 1.32 52702 20542 2 1181.639156 591.8295 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3799 - 875360 - - - -4.4878 - 2.282 0.449 - 364.1 1 2 0 -0.0053 11 0 0 0 2.88E+07 2.19E+07 - - - 4.5876 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.20543.20543.2 0.00143 16-Aug R.LVSYYYFLR.F sp|Q7LGA3|HS2ST_HUMAN 1 1222.6386 0.86 52703 20543 2 1222.638039 612.3266 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 8.5 3799.2 - 868047 - - - -0.4965 - 1.715 0.473 - 200.9 1 2 0 -0.0006 9 0 0 0 2.30E+07 2.68E+07 - - - 4.0949 1 230117_WJC_METTL3_WT_vs_EV_F06.20544.20544.2 1.79E-05 14/34 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.79 52704 20544 2 1968.07257 985.0433 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3799.3 - 703798 - - - 0.2642 - 2.311 0.551 - 344.1 1 2 0 0.0005 18 0 0 0 4.62E+06 2.58E+06 - - - 5.17 1 230117_WJC_METTL3_WT_vs_EV_F06.20546.20546.2 0.00368 20-Nov K.FMELLEPLNER.K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1389.6962 0.57 52706 20546 2 1389.695509 695.8554 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.25 3799.5 - 660726 - - - -0.5239 - 2.3 0.455 - 557.1 1 2 0 -0.0007 11 0 0 0 2.83E+06 4.94E+06 - - - 4.6546 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.20547.20547.2 0.00665 16-Jul K.DLSDFPLIK.K "sp|P20585|MSH3_HUMAN,tr|A0A590UJN8|A0A590UJN8_HUMAN,tr|A0A590UKC9|A0A590UKC9_HUMAN,tr|A0A590UJW0|A0A590UJW0_HUMAN" 4 1046.5648 1.61 52707 20547 2 1046.564129 524.2897 DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4 4.21 3799.7 - 540790 - - - -0.6526 - 1.497 0.35 - 115.7 1 2 0 -0.0007 9 0 0 0 5.59E+06 3.46E+06 - - - 2.7931 0.9954 230117_WJC_METTL3_WT_vs_EV_F06.20550.20550.2 0.0383 16-Jul R.GIGFGDIFK.E sp|Q9Y5K6|CD2AP_HUMAN 1 952.5018 0.57 52710 20550 2 952.500814 477.2582 CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1 5.84 3800.1 - 416135 - - - -1.0541 - 1.254 0.299 - 104.5 1 2 0 -0.001 9 0 0 0 3.54E+06 6.25E+06 - - - 1.9039 1 230117_WJC_METTL3_WT_vs_EV_F06.20551.20551.2 0.000996 13/20 R.LLGAALPLLTK[136.11].E "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1116.7362 0.69 52711 20551 2 1116.736212 559.3754 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 8.75 3800.2 - 401839 - - - 0.0269 - 2.243 0.457 - 318.1 1 2 0 0 11 0 0 0 4.97E+06 7.17E+06 - - - 4.6017 0.9361 230117_WJC_METTL3_WT_vs_EV_F06.20553.20553.2 1.72 18-Aug R.EYLLDMIPPR.S "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 3 1245.6427 2.11 52713 20553 2 1245.641109 623.8286 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.37 3800.5 - 298881 - - - -1.3134 - 0.935 0.155 - 130.7 1 2 0 -0.0016 10 0 0 0 3.52E+06 1.67E+06 - - - -0.0023 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.20556.20556.2 0.000193 20-Jul K.GVPTGFILPIR.D "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1168.6968 12.15 52715 20556 2 1168.696206 585.3557 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 3800.8 - 908315 - - - -0.5331 - 1.675 0.184 - 113.2 1 2 0 -0.0006 11 0 0 0 1.63E+07 1.34E+06 - - - 1.7952 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.20564.20564.2 0.00261 20-Nov K.GIFNGFSVTLK[136.11].E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1189.6587 1.3 52720 20564 2 1189.663772 595.8366 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3801.8 - 992485 - - - 4.2979 - 2.026 0.394 - 273.4 1 2 0 0.0051 11 0 0 0 2.88E+07 2.22E+07 - - - 3.8595 0.9645 230117_WJC_METTL3_WT_vs_EV_F06.20568.20568.2 0.00303 16-Aug K.C[160.03]MPTFQFFK.K sp|P10599|THIO_HUMAN 1 1204.5409 2.85 52724 20568 2 1204.535006 603.2777 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3802.2 - 1.14E+06 - - - -4.9122 - 1.272 0.339 - 149.2 1 2 0 -0.0059 9 0 0 0 4.16E+07 1.46E+07 - - - 2.239 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.20570.20570.2 0.0298 16-Jul R.LVFGFLNGR.A "sp|P00491|PNPH_HUMAN,tr|G3V2H3|G3V2H3_HUMAN,tr|G3V5M2|G3V5M2_HUMAN" 3 1021.5709 3.33 52726 20570 2 1021.570746 511.7927 Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2 9.75 3802.4 - 459107 - - - -0.1517 - 1.267 0.385 - 165 1 2 0 -0.0002 9 0 0 0 7.49E+06 2.25E+06 - - - 2.5692 1 230117_WJC_METTL3_WT_vs_EV_F06.20576.20576.2 3.25E-08 15/24 R.GAVGALLVYDIAK.H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1288.7391 1.48 52730 20576 2 1288.742079 645.3768 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3803.2 - 4.91E+06 - - - 2.3209 - 3.038 0.602 - 1191.2 1 2 0 0.003 13 0 0 0 5.23E+07 3.54E+07 - - - 6.3384 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20578.20578.2 0.0109 22-Jun R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 4034.71 52731 20578 2 1603.766867 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3803.4 - 2.00E+08 - - - 1.8251 - 1.528 0.426 - 100.4 1 2 0 0.0029 12 0 0 0 6.64E+09 1.65E+06 - - - 3.302 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.20580.20580.2 0.0246 16-Jul K.C[160.03]MPTFQFFK[136.11].K sp|P10599|THIO_HUMAN 1 1212.5551 2.85 52733 20580 2 1212.556251 607.2848 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3803.6 - 920963 - - - 0.9303 - 1.13 0.364 - 99.1 1 2 0 0.0011 9 0 0 0 4.16E+07 1.46E+07 - - - 2.0827 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.20581.20581.2 0.222 16-Sep K.IQLPIIQLR.K sp|O15111|IKKA_HUMAN 1 1092.7019 3.88 52734 20581 2 1092.701481 547.3582 Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Homo sapiens OX=9606 GN=CHUK PE=1 SV=2 9.75 3803.7 - 852211 - - - -0.3972 - 1.84 0.186 - 264.2 1 2 0 -0.0004 9 0 0 0 6.75E+06 1.74E+06 - - - 2.1787 1 230117_WJC_METTL3_WT_vs_EV_F06.20585.20585.2 2.22E-05 20-Oct K.YFFFDDGNGLK.G sp|P61009|SPCS3_HUMAN 1 1321.5979 0.75 52738 20585 2 1321.59836 661.8062 Signal peptidase complex subunit 3 OS=Homo sapiens OX=9606 GN=SPCS3 PE=1 SV=1 4.21 3804.3 - 235004 - - - 0.3458 - 2.049 0.564 - 256.9 1 2 0 0.0005 11 0 0 0 4.42E+06 5.88E+06 - - - 5.1472 1 230117_WJC_METTL3_WT_vs_EV_F06.20588.20588.2 4.32E-06 16/24 R.GAVGALLVYDIAK[136.11].H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1296.7533 1.48 52740 20588 2 1296.754831 649.3839 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3804.6 - 1.25E+07 - - - 1.1899 - 3.392 0.545 - 1467.3 1 2 0 0.0015 13 0 0 0 5.23E+07 3.54E+07 - - - 6.2007 0.999 230117_WJC_METTL3_WT_vs_EV_F06.20591.20591.2 0.00145 18-Oct R.IYLDMLNVYK.C "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 11 1270.6631 1.25 52742 20591 2 1270.663134 636.3388 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.83 3805 - 1.04E+06 - - - -0.0094 - 1.851 0.277 - 243.8 1 2 0 0 10 0 0 0 6.73E+06 5.37E+06 - - - 2.8056 1 230117_WJC_METTL3_WT_vs_EV_F06.20592.20592.2 0.00318 15/24 K.ILESSQTLLSVLK.R "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1429.8392 6.49 52743 20592 2 1429.837161 715.9269 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 6 3805.1 - 515334 - - - -1.4232 - 2.443 0.518 - 593.3 1 2 0 -0.002 13 0 0 0 9.48E+06 1.46E+06 - - - 5.1588 0.9913 230117_WJC_METTL3_WT_vs_EV_F06.20594.20594.2 1.69 14-Jul K.DFLPIEIR.G sp|Q5VT06|CE350_HUMAN 1 1001.5546 1.91 52745 20594 2 1001.557892 501.7846 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.37 3805.4 - 378984 - - - 3.3049 - 1.565 0.104 - 195.1 1 2 0 0.0033 8 0 0 0 2.87E+06 1.50E+06 - - - 1.1589 0.8532 230117_WJC_METTL3_WT_vs_EV_F06.20597.20597.2 0.0326 20-Jul V.VVGFSAALGYR[166.11].Y "sp|Q9HBW9|AGRL4_HUMAN,tr|A0A590UJX8|A0A590UJX8_HUMAN,tr|B1AR72|B1AR72_HUMAN,tr|A0A590UJN9|A0A590UJN9_HUMAN" 4 1148.6218 0.03 52748 20597 2 1148.621499 575.3182 Adhesion G protein-coupled receptor L4 OS=Homo sapiens OX=9606 GN=ADGRL4 PE=1 SV=3 8.72 3805.7 - 323082 - - - -0.2307 - 1.578 0.269 - 121.9 2 1 0 -0.0003 11 0 0 0 1.05E+06 3.10E+07 - - - 2.1273 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.20598.20598.2 0.0063 18-Jul K.DSPFGLSFVR.F "sp|P18887|XRCC1_HUMAN,tr|M0R1U8|M0R1U8_HUMAN,tr|M0R0D2|M0R0D2_HUMAN,tr|M0QYS5|M0QYS5_HUMAN,tr|F5H8D7|F5H8D7_HUMAN,tr|M0QZ96|M0QZ96_HUMAN" 6 1123.5662 1.97 52749 20598 2 1123.565369 562.7904 DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2 5.84 3805.9 - 239443 - - - -0.7476 - 1.303 0.325 - 157.5 1 2 0 -0.0008 10 0 0 0 3.27E+06 1.66E+06 - - - 2.18 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.20599.20599.2 0.000374 18-Aug R.LWNETVELFR[166.11].A sp|Q8WUY9|DEP1B_HUMAN 1 1315.68 0.83 52750 20599 2 1315.677952 658.8473 DEP domain-containing protein 1B OS=Homo sapiens OX=9606 GN=DEPDC1B PE=1 SV=2 4.53 3806 - 238178 - - - -1.5619 - 1.779 0.357 - 222.7 1 2 0 -0.0021 10 0 0 0 2.32E+06 2.81E+06 - - - 3.2851 1 230117_WJC_METTL3_WT_vs_EV_F06.20601.20601.2 0.00359 16/26 K.IPVTIITGYLGAGK.T "sp|Q5RIA9|CBWD5_HUMAN,sp|Q9BRT8|CBWD1_HUMAN,sp|Q5JTY5|CBWD3_HUMAN,sp|Q4V339|CBWD6_HUMAN,sp|Q8IUF1|CBWD2_HUMAN,tr|A0A087WZQ3|A0A087WZQ3_HUMAN,tr|Q5JTY2|Q5JTY2_HUMAN,tr|Q6NVZ8|Q6NVZ8_HUMAN,tr|A0A0B4J2E3|A0A0B4J2E3_HUMAN,tr|A0A087X140|A0A087X140_HUMAN,tr|F8WEU0|F8WEU0_HUMAN,tr|E7EUZ7|E7EUZ7_HUMAN,tr|F8WEG4|F8WEG4_HUMAN,tr|A0A087WYD2|A0A087WYD2_HUMAN,tr|A0A0A0MRU4|A0A0A0MRU4_HUMAN,tr|Q5RIB0|Q5RIB0_HUMAN,tr|H0Y5V3|H0Y5V3_HUMAN,tr|A0A0A6YYH9|A0A0A6YYH9_HUMAN,tr|A0A087WWG3|A0A087WWG3_HUMAN,tr|A0A087WTC0|A0A087WTC0_HUMAN,tr|C9J3G2|C9J3G2_HUMAN,tr|F2Z2T4|F2Z2T4_HUMAN,tr|Q5RIB5|Q5RIB5_HUMAN" 23 1401.8232 4.55 52752 20601 2 1401.823067 701.9189 COBW domain-containing protein 5 OS=Homo sapiens OX=9606 GN=CBWD5 PE=2 SV=1 8.59 3806.3 - 236023 - - - -0.0606 - 3.161 0.418 - 836 1 2 0 -0.0001 14 0 0 0 2.98E+06 6.55E+05 - - - 5.0164 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.20603.20603.2 0.00122 20-Oct R.LFLQFVTGSPR.L "sp|Q14669|TRIPC_HUMAN,tr|A0A6Q8PHK0|A0A6Q8PHK0_HUMAN,tr|H7C2Y1|H7C2Y1_HUMAN,tr|A0A6Q8PGG9|A0A6Q8PGG9_HUMAN" 4 1263.6976 2.53 52754 20603 2 1263.701513 632.8561 E3 ubiquitin-protein ligase TRIP12 OS=Homo sapiens OX=9606 GN=TRIP12 PE=1 SV=1 9.75 3806.5 - 198893 - - - 3.1297 - 2.129 0.32 - 403.4 1 2 0 0.004 11 0 0 0 2.24E+06 8.86E+05 - - - 3.4475 1 230117_WJC_METTL3_WT_vs_EV_F06.20604.20604.2 1.09E-15 17/30 R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 12.11 52755 20604 2 1756.898127 879.4608 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3806.6 - 142619 - - - -5.0264 - 3.7 0.582 - 1133.9 1 2 0 -0.0088 16 0 0 0 4.43E+07 3.66E+06 - - - 6.5535 0.978 230117_WJC_METTL3_WT_vs_EV_F06.20607.20607.2 0.000159 13/22 R.VIQELLVDYYVK.L "sp|Q9H6D7|HAUS4_HUMAN,tr|H0YJ09|H0YJ09_HUMAN,tr|G3V4X7|G3V4X7_HUMAN,tr|G3V5A5|G3V5A5_HUMAN,tr|G3V541|G3V541_HUMAN,tr|H0YIZ6|H0YIZ6_HUMAN,tr|G3V5Z2|G3V5Z2_HUMAN" 7 1480.8177 -1 52758 20607 2 1480.80847 741.4161 HAUS augmin-like complex subunit 4 OS=Homo sapiens OX=9606 GN=HAUS4 PE=1 SV=1 4.37 3807 - 96212.3 - - - -6.2553 - 2.077 0.42 - 617.1 1 2 0 -0.0093 12 0 0 0 0.00E+00 0.00E+00 - - - 4.0634 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.20611.20611.3 1.02E-05 Nov-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 52761 20611 3 1603.768669 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3807.5 - 1.59E+07 - - - 2.9487 - 1.98 0.521 - 181.9 1 2 0 0.0047 12 0 0 0 6.67E+08 0.00E+00 - - - 6.2408 0.999 230117_WJC_METTL3_WT_vs_EV_F06.20616.20616.2 0.492 12-Sep R.EIALWFR[166.11].A "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 943.5155 1.33 52766 20616 2 943.516108 472.765 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6.1 3808.1 - 641268 - - - 0.6359 - 1.772 0.228 - 369.2 1 2 0 0.0006 7 0 0 0 8.45E+06 6.34E+06 - - - 2.5376 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.20618.20618.2 0.000238 18-Oct K.IMLPWDPTGK[136.11].L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1164.6093 1.73 52768 20618 2 1164.608011 583.3119 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3808.3 - 436200 - - - -1.0776 - 1.745 0.47 - 375.9 1 2 0 -0.0013 10 0 0 0 4.56E+07 2.63E+07 - - - 4.0661 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.20619.20619.2 0.344 18-Nov R.IYLDMLNVYK[136.11].C "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 11 1278.6773 2.65 52769 20619 2 1278.679976 640.3459 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.83 3808.5 - 174177 - - - 2.0568 - 1.896 0.288 - 314.6 1 2 0 0.0026 10 0 0 0 1.84E+07 6.94E+06 - - - 2.9531 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.20624.20624.2 0.00646 16-Jun R.FTGLESIFR[166.11].A sp|Q8N4Q0|PTGR3_HUMAN 1 1078.5687 0.71 52773 20624 2 1078.56928 540.2916 Prostaglandin reductase 3 OS=Homo sapiens OX=9606 GN=ZADH2 PE=1 SV=1 6 3809.1 - 177000 - - - 0.5702 - 1.276 0.34 - 119 1 2 0 0.0006 9 0 0 0 3.57E+07 5.07E+07 - - - 2.2572 1 230117_WJC_METTL3_WT_vs_EV_F06.20625.20625.2 1.41E-08 17/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 52774 20625 2 1343.612966 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3809.2 - 384379 - - - 1.1194 - 2.973 0.541 - 1163 1 1 0 0.0015 10 0 0 0 3.08E+07 0.00E+00 - - - 6.0777 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.20626.20626.2 0.000128 22-Jul K.IGLIQFC[160.03]LSAPK.T sp|P50991|TCPD_HUMAN 1 1345.7428 9.27 52775 20626 2 1345.745875 673.8787 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3809.2 - 655766 - - - 2.2894 - 1.513 0.389 - 154.1 1 2 0 0.0031 12 0 0 0 1.26E+08 1.36E+07 - - - 3.0027 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20627.20627.2 2.01E-05 18-Aug R.AFDLFNPNFK.S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1211.5975 1.47 52776 20627 2 1211.599837 606.806 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3809.2 - 497122 - - - 1.9214 - 1.858 0.505 - 172.2 1 2 0 0.0023 10 0 0 0 3.03E+07 2.06E+07 - - - 4.4994 1 230117_WJC_METTL3_WT_vs_EV_F06.20628.20628.2 3.21E-10 19/28 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.3 52777 20628 2 1548.924693 775.4692 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3809.3 - 317121 - - - 0.4932 - 3.729 0.621 - 858 1 2 0 0.0008 15 0 0 0 6.94E+07 5.33E+07 - - - 6.8633 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20629.20629.2 8.47E-05 14-Oct K.FGFYEVFK[136.11].V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1043.5208 0.96 52778 20629 2 1043.521009 522.7677 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3809.4 - 250797 - - - 0.23 - 1.886 0.491 - 204.1 1 2 0 0.0002 8 0 0 0 2.40E+07 2.51E+07 - - - 4.5809 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20630.20630.2 2.35E-08 20-Dec K.WYLENVYPELR[166.11].V sp|Q10471|GALT2_HUMAN 1 1490.7433 1.02 52779 20630 2 1490.744843 746.3789 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3809.5 - 199506 - - - 1.0116 - 2.331 0.415 - 645.3 1 2 0 0.0015 11 0 0 0 3.60E+07 3.53E+07 - - - 4.3952 0.9886 230117_WJC_METTL3_WT_vs_EV_F06.20634.20634.2 0.0502 18-Jul K.IMLPWDPTGK.L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1156.5951 1.73 52781 20634 2 1156.590441 579.3048 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3809.9 - 4.35E+06 - - - -3.9988 - 1.49 0.372 - 178.1 1 2 0 -0.0046 10 0 0 0 4.56E+07 2.63E+07 - - - 2.9002 1 230117_WJC_METTL3_WT_vs_EV_F06.20636.20636.3 4.32E-07 14/60 R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 22.97 52783 20636 3 1756.908322 586.6429 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3810.1 - 5.98E+06 - - - 0.7764 - 2.62 0.506 - 275.3 1 2 0 0.0014 16 0 0 0 2.09E+07 9.10E+05 - - - 6.6524 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20637.20637.2 0.00375 14-Aug K.FGFYEVFK.V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1035.5066 0.96 52784 20637 2 1035.508232 518.7606 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3810.2 - 3.75E+06 - - - 1.606 - 1.731 0.368 - 148.7 1 2 0 0.0017 8 0 0 0 2.40E+07 2.51E+07 - - - 3.4134 1 230117_WJC_METTL3_WT_vs_EV_F06.20638.20638.2 1.44E-05 20-Aug K.WYLENVYPELR.V sp|Q10471|GALT2_HUMAN 1 1480.7351 1.02 52785 20638 2 1480.736799 741.3748 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3810.2 - 3.65E+06 - - - 1.171 - 1.962 0.525 - 228.8 1 2 0 0.0017 11 0 0 0 3.60E+07 3.53E+07 - - - 4.7413 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.20640.20640.2 0.0073 18-Aug K.DLIGVQNLLK.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1111.6601 1.05 52787 20640 2 1111.661028 556.8373 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3810.3 - 2.35E+06 - - - 0.8258 - 1.621 0.303 - 184.3 1 2 0 0.0009 10 0 0 0 1.62E+07 1.54E+07 - - - 2.627 0.9602 230117_WJC_METTL3_WT_vs_EV_F06.20641.20641.2 4.58 18-May K.DLIGVQNLLK[136.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1119.6743 1.03 52788 20641 2 1119.674955 560.8444 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3810.3 - 2.33E+06 - - - 0.5761 - 0.927 0.109 - 70.5 1 2 0 0.0006 10 0 0 0 1.58E+07 1.54E+07 - - - -0.3657 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.20642.20642.2 0.00343 16-Aug R.FVC[160.03]PVILFK[136.11].G "sp|Q8NCE2|MTMRE_HUMAN,tr|B4DJ23|B4DJ23_HUMAN" 2 1129.6449 0.58 52789 20642 2 1129.643703 565.8297 Myotubularin-related protein 14 OS=Homo sapiens OX=9606 GN=MTMR14 PE=1 SV=2 8.22 3810.4 - 2.20E+06 - - - -1.0809 - 1.475 0.432 - 181 1 2 0 -0.0012 9 0 0 0 5.70E+06 9.87E+06 - - - 3.3558 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20643.20643.2 0.000825 18-Oct R.LGGIAYFLSR[166.11].L "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1105.616 1.08 52790 20643 2 1105.616223 553.8153 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 8.75 3810.4 - 2.12E+06 - - - 0.2469 - 2.162 0.365 - 316.2 1 2 0 0.0003 10 0 0 0 1.50E+07 1.38E+07 - - - 3.889 1 230117_WJC_METTL3_WT_vs_EV_F06.20644.20644.2 8.77E-06 28-Nov K.LLGASELPIVTPALR[166.11].A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1558.9322 1.3 52791 20644 2 1558.934017 780.4734 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3810.5 - 1.99E+06 - - - 1.1662 - 2.701 0.543 - 220.7 1 2 0 0.0018 15 0 0 0 6.94E+07 5.33E+07 - - - 5.4939 1 230117_WJC_METTL3_WT_vs_EV_F06.20645.20645.2 5.05E-05 22-Nov K.IGLIQFC[160.03]LSAPK[136.11].T sp|P50991|TCPD_HUMAN 1 1353.757 9.27 52792 20645 2 1353.758717 677.8858 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3810.5 - 1.98E+06 - - - 1.2728 - 2.478 0.502 - 458.4 1 2 0 0.0017 12 0 0 0 1.26E+08 1.36E+07 - - - 5.1359 1 230117_WJC_METTL3_WT_vs_EV_F06.20647.20647.2 2.51E-05 30-Dec R.LMNETTAVALAYGIYK[136.11].Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1764.9212 -1 52794 20647 2 1764.929679 883.4679 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3810.8 - 1.24E+06 - - - 4.828 - 2.831 0.545 - 450 1 2 0 0.0085 16 0 0 0 0.00E+00 0.00E+00 - - - 5.6221 0.9977 230117_WJC_METTL3_WT_vs_EV_F06.20648.20648.2 0.0093 18-Aug R.ISYSLFTALR[166.11].V "sp|Q53GQ0|DHB12_HUMAN,tr|E9PI21|E9PI21_HUMAN,tr|A0A1B0GW85|A0A1B0GW85_HUMAN,tr|A0A1B0GU83|A0A1B0GU83_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN" 5 1179.6527 1.35 52795 20648 2 1179.657296 590.8336 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 8.75 3810.8 - 992986 - - - 3.8715 - 1.722 0.296 - 141.7 1 2 0 0.0046 10 0 0 0 7.44E+06 5.51E+06 - - - 2.7429 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.20654.20654.2 12.6 18-Nov K.ILDVLEEIPK.N "sp|Q16718|NDUA5_HUMAN,tr|C9IZN5|C9IZN5_HUMAN,tr|H7BYD0|H7BYD0_HUMAN,tr|A0A087X1G1|A0A087X1G1_HUMAN,tr|F8WAS3|F8WAS3_HUMAN,tr|A0A7I2V2W4|A0A7I2V2W4_HUMAN,tr|A0A7I2V3L8|A0A7I2V3L8_HUMAN" 7 1167.6751 2.25 52799 20654 2 1167.674097 584.8448 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3 4.14 3811.5 - 1.15E+07 - - - -0.8513 - 2.095 0.307 - 270.7 1 2 0 -0.001 10 0 0 0 3.20E+07 1.42E+07 - - - 3.3725 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.20655.20655.2 0.0253 18-Dec K.ILDVLEEIPK[136.11].N "sp|Q16718|NDUA5_HUMAN,tr|C9IZN5|C9IZN5_HUMAN,tr|H7BYD0|H7BYD0_HUMAN,tr|A0A087X1G1|A0A087X1G1_HUMAN,tr|F8WAS3|F8WAS3_HUMAN,tr|A0A7I2V2W4|A0A7I2V2W4_HUMAN,tr|A0A7I2V3L8|A0A7I2V3L8_HUMAN" 7 1175.6893 2.25 52800 20655 2 1175.687933 588.8519 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3 4.14 3811.6 - 5.42E+06 - - - -1.1551 - 2.325 0.373 - 313.5 1 2 0 -0.0014 10 0 0 0 3.20E+07 1.42E+07 - - - 4.1506 1 230117_WJC_METTL3_WT_vs_EV_F06.20657.20657.2 0.000236 14/22 R.VPFLVLEC[160.03]PNLK[136.11].L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1435.7989 -1 52802 20657 2 1435.79672 718.9067 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3811.8 - 5.01E+06 - - - -1.4891 - 2.246 0.476 - 470.1 1 2 0 -0.0021 12 0 0 0 0.00E+00 0.00E+00 - - - 4.6851 1 230117_WJC_METTL3_WT_vs_EV_F06.20658.20658.2 0.0174 15/22 R.VPFLVLEC[160.03]PNLK.L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1427.7847 -1 52803 20658 2 1427.782957 714.8996 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3811.9 - 4.75E+06 - - - -1.1914 - 2.718 0.463 - 967.9 1 2 0 -0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 5.0911 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.20659.20659.2 0.000285 22-Sep K.LVGQSIIAYLQK.K "sp|P53621|COPA_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 3 1331.7813 3.43 52804 20659 2 1331.779097 666.8979 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 8.59 3812 - 3.87E+06 - - - -1.6444 - 1.853 0.412 - 150.6 1 2 0 -0.0022 12 0 0 0 7.47E+06 2.18E+06 - - - 3.7063 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.20662.20662.2 0.133 14-Aug R.ETILNLLR[166.11].K "sp|Q6P158|DHX57_HUMAN,tr|A0A087WZ11|A0A087WZ11_HUMAN" 2 980.5894 0.85 52807 20662 2 980.588222 491.302 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 6.1 3812.4 - 3.34E+06 - - - -1.2023 - 1.818 0.314 - 222.2 1 2 0 -0.0012 8 0 0 0 5.01E+06 5.88E+06 - - - 3.1626 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.20664.20664.2 0.000672 13/20 R.NTISLLVAGLK[136.11].K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1135.7056 1.07 52809 20664 2 1135.70462 568.8601 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.75 3812.7 - 2.17E+06 - - - -0.8717 - 2.225 0.448 - 607.2 1 2 0 -0.001 11 0 0 0 5.18E+06 4.85E+06 - - - 4.5131 0.9876 230117_WJC_METTL3_WT_vs_EV_F06.20665.20665.2 5.76E-05 18-Oct K.FSDFLLDPYK[136.11].Y sp|Q9UIG0|BAZ1B_HUMAN 1 1251.6267 -1 52810 20665 2 1251.637166 626.8206 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 4.21 3812.8 - 1.34E+06 - - - 8.3691 - 2.157 0.448 - 231 1 2 0 0.0105 10 0 0 0 0.00E+00 0.00E+00 - - - 4.4924 0.9547 230117_WJC_METTL3_WT_vs_EV_F06.20667.20667.2 0.665 22-Nov R.FLPEFPSC[160.03]SLLK[136.11].E sp|Q9H9A6|LRC40_HUMAN 1 1444.7516 -1 52812 20667 2 1444.750493 723.3831 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.99 3813.1 - 1.23E+06 - - - -0.7482 - 1.319 0.031 - 144.2 1 2 0 -0.0011 12 0 0 0 0.00E+00 0.00E+00 - - - -0.0019 1 230117_WJC_METTL3_WT_vs_EV_F06.20668.20668.2 9.76E-05 20-Dec K.IFGVTTLDIVR.A "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1232.7129 1.04 52813 20668 2 1232.707582 617.3637 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 5.84 3813.2 - 1.23E+06 - - - -4.2922 - 2.344 0.473 - 579.5 1 2 0 -0.0053 11 0 0 0 8.15E+06 7.84E+06 - - - 4.8374 0.9968 230117_WJC_METTL3_WT_vs_EV_F06.20669.20669.2 0.0136 16-Sep R.NALDLLLPK[136.11].L "sp|P30566|PUR8_HUMAN,tr|A0A096LNY5|A0A096LNY5_HUMAN,tr|A0A1B0GTJ7|A0A1B0GTJ7_HUMAN,tr|A0A1B0GWJ0|A0A1B0GWJ0_HUMAN,tr|A0A1B0GWF8|A0A1B0GWF8_HUMAN,tr|A0A096LNY4|A0A096LNY4_HUMAN,tr|A0A1B0GTG9|A0A1B0GTG9_HUMAN,tr|A0A7P0T9A7|A0A7P0T9A7_HUMAN,tr|A0A096LNY6|A0A096LNY6_HUMAN,tr|A0A096LP92|A0A096LP92_HUMAN,tr|A0A7P0Z472|A0A7P0Z472_HUMAN" 11 1003.6157 1.85 52814 20669 2 1003.614087 502.8151 Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2 5.84 3813.3 - 1.21E+06 - - - -1.6391 - 1.671 0.29 - 147.4 1 2 0 -0.0016 9 0 0 0 9.71E+06 5.24E+06 - - - 2.6678 1 230117_WJC_METTL3_WT_vs_EV_F06.20675.20675.2 4.06E-06 22-Dec K.GIDPFSLDALSK[136.11].E sp|P40227|TCPZ_HUMAN 1 1269.6696 9.74 52819 20675 2 1269.670927 635.8421 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3814.1 - 1.55E+06 - - - 1.031 - 2.452 0.562 - 387.2 1 2 0 0.0013 12 0 0 0 1.56E+08 1.60E+07 - - - 5.5514 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20676.20676.2 0.012 16-Sep K.TEILPPFFK.H sp|O75533|SF3B1_HUMAN 1 1090.6063 1.05 52820 20676 2 1090.607018 546.3104 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.66 3814.2 - 1.43E+06 - - - 0.6739 - 1.738 0.396 - 323.1 1 2 0 0.0007 9 0 0 0 2.84E+07 2.71E+07 - - - 3.5647 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20677.20677.2 0.00293 16-Oct K.TEILPPFFK[136.11].H sp|O75533|SF3B1_HUMAN 1 1098.6205 1.05 52821 20677 2 1098.62134 550.3175 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.66 3814.3 - 1.32E+06 - - - 0.7801 - 1.963 0.383 - 425.5 1 2 0 0.0009 9 0 0 0 2.84E+07 2.71E+07 - - - 3.8209 1 230117_WJC_METTL3_WT_vs_EV_F06.20678.20678.2 1.87E-05 16-Oct R.FYNLVLLPR[166.11].V "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1143.668 1.21 52822 20678 2 1143.668897 572.8413 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 3814.4 - 945678 - - - 0.7966 - 2.131 0.574 - 425.5 1 2 0 0.0009 9 0 0 0 1.62E+07 1.34E+07 - - - 5.4691 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20679.20679.2 0.000133 16-Sep R.FYNLVLLPR.V "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1133.6597 1.21 52823 20679 2 1133.660172 567.8371 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 3814.6 - 831736 - - - 0.4022 - 1.892 0.493 - 330.4 1 2 0 0.0005 9 0 0 0 1.62E+07 1.34E+07 - - - 4.5269 1 230117_WJC_METTL3_WT_vs_EV_F06.20680.20680.2 0.000637 20-Dec K.ILLTQENPFFR[166.11].K sp|Q08J23|NSUN2_HUMAN 1 1386.7535 2.52 52824 20680 2 1386.755437 694.384 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3814.7 - 821634 - - - 1.3925 - 2.473 0.458 - 558.7 1 2 0 0.0019 11 0 0 0 4.77E+07 1.89E+07 - - - 4.8726 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20684.20684.2 0.000396 13/20 R.NTISLLVAGLK.K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1127.6914 1.07 52828 20684 2 1127.692204 564.853 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.75 3815.2 - 456550 - - - 0.7041 - 2.487 0.409 - 602.5 1 2 0 0.0008 11 0 0 0 5.18E+06 4.85E+06 - - - 4.5263 0.9371 230117_WJC_METTL3_WT_vs_EV_F06.20690.20690.2 0.176 12-Oct L.PLQDVYK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 861.4596 6.12 52834 20690 2 861.460302 431.7371 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.26 3816 - 200650 - - - 0.7928 - 1.984 0.194 - 371.6 1 1 0 0.0007 7 0 0 0 2.16E+06 3.53E+05 - - - 2.6445 1 230117_WJC_METTL3_WT_vs_EV_F06.20691.20691.2 5.06E-06 14/24 K.ILGVWDTAVSLGK.L sp|Q53RT3|APRV1_HUMAN 1 1357.7606 999 52835 20691 2 1357.760647 679.8876 Retroviral-like aspartic protease 1 OS=Homo sapiens OX=9606 GN=ASPRV1 PE=1 SV=1 5.84 3816.1 - 141138 - - - 0.07 - 2.673 0.567 - 627.5 1 2 0 0.0001 13 0 0 0 4.42E+06 0.00E+00 - - - 5.7522 1 230117_WJC_METTL3_WT_vs_EV_F06.20695.20695.2 0.00312 13/20 K.FLFVDADQIVR.T sp|Q9NYU2|UGGG1_HUMAN 1 1321.703 4.75 52838 20695 2 1321.702033 661.8588 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.21 3816.6 - 5.46E+06 - - - -0.7596 - 2.439 0.431 - 548.7 1 2 0 -0.001 11 0 0 0 1.43E+07 3.00E+06 - - - 4.636 1 230117_WJC_METTL3_WT_vs_EV_F06.20696.20696.2 1.15E-07 17/28 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 999 52839 20696 2 1658.9045 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3816.7 - 5.33E+06 - - - -2.753 - 3.455 0.55 - 1028 1 2 0 -0.0046 15 0 0 0 1.44E+08 0.00E+00 - - - 6.15 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.20697.20697.3 3.39E-06 18/56 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 768.05 52840 20697 3 1658.907114 553.977 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3816.7 - 3.39E+06 - - - -1.1773 - 3.447 0.494 - 440.6 1 2 0 -0.002 15 0 0 0 7.56E+07 9.84E+04 - - - 7.2762 1 230117_WJC_METTL3_WT_vs_EV_F06.20698.20698.2 7.23E-08 17/22 R.VPDGMVGLIIGR.G "sp|Q92945|FUBP2_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 1225.6853 2.32 52841 20698 2 1225.685232 613.8499 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.81 3816.9 - 3.35E+06 - - - -0.0375 - 2.738 0.622 - 1222.7 1 2 0 0 12 0 0 0 1.56E+07 6.74E+06 - - - 6.2853 1 230117_WJC_METTL3_WT_vs_EV_F06.20699.20699.2 2.63E-05 16-Oct R.YLTVAAIFR.G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1052.6019 -1 52842 20699 2 1052.601302 527.3082 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3817 - 2.01E+06 - - - -0.5358 - 1.974 0.518 - 343.4 1 2 0 -0.0006 9 0 0 0 0.00E+00 0.00E+00 - - - 4.8342 0.9298 230117_WJC_METTL3_WT_vs_EV_F06.20701.20701.2 0.00336 20-Dec K.LTPLILKPFGN.S "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1211.7278 -1 52844 20701 2 1211.726561 606.8712 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 8.75 3817.3 - 1.61E+06 - - - -1.0184 - 1.844 0.423 - 488.1 1 1 0 -0.0012 11 0 0 0 0.00E+00 0.00E+00 - - - 3.8203 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.20703.20703.2 0.000388 14-Jul K.ETLLAMFK.Y sp|P26639|SYTC_HUMAN 1 951.5099 -1 52846 20703 2 951.508405 476.7622 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 6.1 3817.5 - 1.04E+06 - - - -1.6132 - 1.578 0.407 - 159.8 1 2 0 -0.0015 8 0 0 0 0.00E+00 0.00E+00 - - - 3.4224 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.20705.20705.3 1.34E-07 17/56 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.5 52848 20705 3 1548.922635 517.3153 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3817.8 - 833392 - - - -0.8354 - 3.106 0.5 - 497.5 1 2 0 -0.0013 15 0 0 0 3.98E+06 2.66E+06 - - - 7.0714 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.20709.20709.2 0.00028 22-Oct R.YGLFPANYVELR[166.11].Q sp|Q14247|SRC8_HUMAN 1 1450.7484 1.67 52852 20709 2 1450.745238 726.3815 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 6 3818.3 - 653899 - - - -2.194 - 2.209 0.424 - 226.8 1 2 0 -0.0032 12 0 0 0 8.87E+06 5.31E+06 - - - 4.257 1 230117_WJC_METTL3_WT_vs_EV_F06.20710.20710.2 8.38E-08 14/26 K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.07 52853 20710 2 1408.827358 705.4218 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3818.4 - 552483 - - - -1.1414 - 2.851 0.503 - 799.3 1 2 0 -0.0016 14 0 0 0 7.56E+07 7.04E+07 - - - 5.3847 1 230117_WJC_METTL3_WT_vs_EV_F06.20711.20711.2 3.66E-06 14/26 K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.07 52854 20711 2 1416.839222 709.4289 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3818.5 - 547110 - - - -2.7837 - 2.829 0.533 - 743.5 1 2 0 -0.0039 14 0 0 0 7.56E+07 7.04E+07 - - - 5.5861 0.993 230117_WJC_METTL3_WT_vs_EV_F06.20712.20712.2 0.00943 14-Jun K.ETLLAMFK[136.11].Y sp|P26639|SYTC_HUMAN 1 959.5241 -1 52855 20712 2 959.521976 480.7693 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 6.1 3818.7 - 437426 - - - -2.2553 - 1.393 0.314 - 87.3 2 2 0 -0.0022 8 0 0 0 0.00E+00 0.00E+00 - - - 2.2247 0.9868 230117_WJC_METTL3_WT_vs_EV_F06.20715.20715.2 0.694 16-Oct R.NALDLLLPK.L "sp|P30566|PUR8_HUMAN,tr|A0A096LNY5|A0A096LNY5_HUMAN,tr|A0A1B0GTJ7|A0A1B0GTJ7_HUMAN,tr|A0A1B0GWJ0|A0A1B0GWJ0_HUMAN,tr|A0A1B0GWF8|A0A1B0GWF8_HUMAN,tr|A0A096LNY4|A0A096LNY4_HUMAN,tr|A0A1B0GTG9|A0A1B0GTG9_HUMAN,tr|A0A7P0T9A7|A0A7P0T9A7_HUMAN,tr|A0A096LNY6|A0A096LNY6_HUMAN,tr|A0A096LP92|A0A096LP92_HUMAN,tr|A0A7P0Z472|A0A7P0Z472_HUMAN" 11 995.6015 1.85 52857 20715 2 995.600366 498.808 Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2 5.84 3819.2 - 1.32E+06 - - - -1.1712 - 1.579 0.096 - 244.7 1 2 0 -0.0012 9 0 0 0 9.71E+06 5.24E+06 - - - 1.0712 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.20717.20717.2 0.000992 16-Sep R.GFAFVYFER[166.11].L sp|Q13595|TRA2A_HUMAN 1 1144.5581 0.89 52859 20717 2 1144.556759 573.2863 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3819.3 - 1.70E+07 - - - -1.1725 - 1.93 0.388 - 374.3 1 2 0 -0.0013 9 0 0 0 2.92E+07 3.29E+07 - - - 3.8086 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.20719.20719.2 0.377 16-Sep R.GFAFVYFER.L sp|Q13595|TRA2A_HUMAN 1 1134.5498 0.89 52861 20719 2 1134.548654 568.2822 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3819.4 - 1.47E+07 - - - -1.0374 - 1.953 0.411 - 437.3 1 2 0 -0.0012 9 0 0 0 2.92E+07 3.29E+07 - - - 4.0128 0.997 230117_WJC_METTL3_WT_vs_EV_F06.20720.20720.2 0.746 14-Sep R.VIFGLFGK[136.11].T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 887.536 -1 52862 20720 2 887.534191 444.7753 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.72 3819.5 - 1.04E+07 - - - -2.0664 - 1.723 0.325 - 262.4 1 2 0 -0.0018 8 0 0 0 0.00E+00 0.00E+00 - - - 3.0818 0.9954 230117_WJC_METTL3_WT_vs_EV_F06.20723.20723.2 0.23 14-Jul R.VIFGLFGK.T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 879.5218 -1 52865 20723 2 879.520066 440.7682 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.72 3819.7 - 5.65E+06 - - - -2 - 1.477 0.31 - 163.4 1 2 0 -0.0018 8 0 0 0 0.00E+00 0.00E+00 - - - 2.5064 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.20724.20724.2 0.000831 16-Oct K.IGFPWSEIR[166.11].N "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 1113.5847 -1 52866 20724 2 1113.583035 557.7996 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 6 3819.8 - 5.53E+06 - - - -1.4503 - 1.856 0.43 - 250.9 1 2 0 -0.0016 9 0 0 0 0.00E+00 0.00E+00 - - - 4.0056 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.20725.20725.2 0.00556 20-Oct K.LFTAESLIGLK[136.11].N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1198.7053 2.22 52867 20725 2 1198.70371 600.3599 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6 3819.9 - 3.30E+06 - - - -1.3056 - 2.008 0.38 - 234.5 1 2 0 -0.0016 11 0 0 0 1.67E+07 7.55E+06 - - - 3.7331 0.999 230117_WJC_METTL3_WT_vs_EV_F06.20726.20726.2 0.0114 16-Sep R.YLTVAAIFR[166.11].G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1062.6101 -1 52868 20726 2 1062.609305 532.3123 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3820 - 2.64E+06 - - - -0.782 - 2.045 0.32 - 281.8 1 2 0 -0.0008 9 0 0 0 0.00E+00 0.00E+00 - - - 3.4739 0.9938 230117_WJC_METTL3_WT_vs_EV_F06.20728.20728.2 0.0039 12-Jul K.YPVWLWK.R "sp|Q13084|RM28_HUMAN,tr|A2IDC6|A2IDC6_HUMAN,tr|A2IDC7|A2IDC7_HUMAN,tr|Q4TT37|Q4TT37_HUMAN" 4 990.5327 0.69 52870 20728 2 990.529629 496.2736 "39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4" 8.59 3820.2 - 1.13E+06 - - - -3.1246 - 1.455 0.374 - 183.4 1 2 0 -0.0031 7 0 0 0 2.99E+06 4.35E+06 - - - 2.9906 0.9872 230117_WJC_METTL3_WT_vs_EV_F06.20731.20731.2 1.37 22-Jun R.IFGDNFDPDFIK[136.11].Q "sp|Q96BR1|SGK3_HUMAN,tr|E5RJV7|E5RJV7_HUMAN,tr|E5RK28|E5RK28_HUMAN,tr|E5RHY6|E5RHY6_HUMAN,tr|E5RHX2|E5RHX2_HUMAN" 5 1434.6911 -1 52873 20731 2 1434.691145 718.3528 Serine\threonine-protein kinase Sgk3 OS=Homo sapiens OX=9606 GN=SGK3 PE=1 SV=1 3.93 3820.6 - 781998 - - - 0.0439 - 1.015 0.199 - 73.8 1 2 0 0.0001 12 0 0 0 0.00E+00 0.00E+00 - - - 0.55 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.20736.20736.2 0.00601 20-Jul K.ILLTQENPFFR.K sp|Q08J23|NSUN2_HUMAN 1 1376.7452 2.42 52877 20736 2 1376.744066 689.3799 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3821.2 - 4.70E+06 - - - -0.8498 - 1.819 0.432 - 190.8 1 2 0 -0.0012 11 0 0 0 4.55E+07 1.88E+07 - - - 3.8499 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.20737.20737.2 0.000116 22-Aug K.GIDPFSLDALSK.E sp|P40227|TCPZ_HUMAN 1 1261.6554 9.74 52878 20737 2 1261.653397 631.835 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3821.3 - 1.69E+06 - - - -1.6019 - 1.69 0.455 - 154.6 1 2 0 -0.002 12 0 0 0 1.56E+08 1.60E+07 - - - 3.7816 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.20738.20738.3 1.82E-06 Oct-52 K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.19 52879 20738 3 1408.827358 470.6169 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3821.4 - 4.62E+06 - - - -1.1414 - 2.264 0.53 - 137.9 1 2 0 -0.0016 14 0 0 0 8.53E+06 7.20E+06 - - - 6.6201 1 230117_WJC_METTL3_WT_vs_EV_F06.20739.20739.2 6.51E-09 20/34 K.ILDSFAAAPVPTTTLVLK.S sp|P18583|SON_HUMAN 1 1856.0659 1.51 52880 20739 2 1856.065063 929.0402 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3821.5 - 3.65E+06 - - - -0.452 - 3.541 0.616 - 825.4 1 2 0 -0.0008 18 0 0 0 1.10E+07 7.29E+06 - - - 6.6991 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.20740.20740.3 2.82E-05 14/52 K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.19 52881 20740 3 1416.840417 473.2883 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3821.5 - 3.41E+06 - - - -1.9402 - 2.916 0.542 - 249.8 1 2 0 -0.0027 14 0 0 0 8.53E+06 7.20E+06 - - - 7.4261 1 230117_WJC_METTL3_WT_vs_EV_F06.20742.20742.2 5.97E-09 17/34 K.ILDSFAAAPVPTTTLVLK[136.11].S sp|P18583|SON_HUMAN 1 1864.0801 1.51 52883 20742 2 1864.079452 933.0473 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3821.7 - 2.98E+06 - - - -0.3487 - 3.203 0.556 - 514.1 1 2 0 -0.0006 18 0 0 0 1.10E+07 7.29E+06 - - - 6.0094 1 230117_WJC_METTL3_WT_vs_EV_F06.20743.20743.2 7.64E-07 22-Sep R.YGLFPANYVELR.Q sp|Q14247|SRC8_HUMAN 1 1440.7402 1.67 52884 20743 2 1440.740466 721.3774 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 6 3821.9 - 2.81E+06 - - - 0.2186 - 2.265 0.547 - 224.5 1 2 0 0.0003 12 0 0 0 8.87E+06 5.31E+06 - - - 5.2322 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.20744.20744.2 1.23E-05 20-Jul R.GGYFDEFGIIR.D "sp|P11413|G6PD_HUMAN,tr|E7EM57|E7EM57_HUMAN,tr|E7EUI8|E7EUI8_HUMAN" 3 1272.6139 -1 52885 20744 2 1272.611171 637.3142 Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4 4.37 3821.9 - 2.66E+06 - - - -2.135 - 1.597 0.475 - 113.4 1 2 0 -0.0027 11 0 0 0 0.00E+00 0.00E+00 - - - 3.8149 0.999 230117_WJC_METTL3_WT_vs_EV_F06.20745.20745.2 0.00365 18-Oct K.IPGLLGVFQK[136.11].L sp|P55060|XPO2_HUMAN 1 1078.663 -1 52886 20745 2 1078.662266 540.3388 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 8.75 3822.1 - 1.84E+06 - - - -0.6962 - 1.877 0.345 - 223.2 1 2 0 -0.0008 10 0 0 0 0.00E+00 0.00E+00 - - - 3.3465 1 230117_WJC_METTL3_WT_vs_EV_F06.20746.20746.2 1.02E-12 17/30 R.TPEQVAEEEYLLQELR.K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1945.9633 -1 52887 20746 2 1945.958684 973.9889 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3822.2 - 1.27E+06 - - - -2.3654 - 3.655 0.626 - 950.2 1 2 0 -0.0046 16 0 0 0 0.00E+00 0.00E+00 - - - 6.8497 1 230117_WJC_METTL3_WT_vs_EV_F06.20748.20748.2 0.00115 14/26 K.VLFLLGADGGC[160.03]ITR.Q "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1490.7915 -1 52889 20748 2 1490.790307 746.403 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 5.8 3822.5 - 1.14E+06 - - - -0.8237 - 2.396 0.512 - 609.5 1 2 0 -0.0012 14 0 0 0 0.00E+00 0.00E+00 - - - 5.015 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.20749.20749.2 0.00478 12-Jul K.YPVWLWK[136.11].R "sp|Q13084|RM28_HUMAN,tr|A2IDC6|A2IDC6_HUMAN,tr|A2IDC7|A2IDC7_HUMAN,tr|Q4TT37|Q4TT37_HUMAN" 4 998.5469 0.69 52890 20749 2 998.546743 500.2807 "39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4" 8.59 3822.6 - 1.11E+06 - - - -0.1813 - 1.461 0.316 - 196.5 1 2 0 -0.0002 7 0 0 0 2.99E+06 4.35E+06 - - - 2.5762 0.9913 230117_WJC_METTL3_WT_vs_EV_F06.20751.20751.2 0.0561 12-Aug R.LGFDLFK.E "sp|Q9UIV8|SPB13_HUMAN,tr|F8WE70|F8WE70_HUMAN,tr|C9JL93|C9JL93_HUMAN,tr|A0A0A0MQW3|A0A0A0MQW3_HUMAN" 4 838.4589 -1 52892 20751 2 838.456738 420.2367 Serpin B13 OS=Homo sapiens OX=9606 GN=SERPINB13 PE=1 SV=2 5.84 3822.8 - 976138 - - - -2.5666 - 1.489 0.258 - 129.5 1 2 0 -0.0022 7 0 0 0 0.00E+00 0.00E+00 - - - 2.2073 1 230117_WJC_METTL3_WT_vs_EV_F06.20752.20752.2 9.67E-06 26-Nov K.VLFLLGADGGC[160.03]ITR[166.11].Q "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1500.7998 -1 52893 20752 2 1500.80459 751.4072 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 5.8 3823 - 970316 - - - 3.1883 - 2.585 0.521 - 361.4 1 2 0 0.0048 14 0 0 0 0.00E+00 0.00E+00 - - - 5.2709 0.9874 230117_WJC_METTL3_WT_vs_EV_F06.20755.20755.2 0.407 12-May K.LNIWDWK.T sp|O60508|PRP17_HUMAN 1 973.5022 -1 52896 20755 2 973.502045 487.7584 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.84 3823.4 - 603164 - - - -0.1099 - 1.364 0.081 - 79.4 1 2 0 -0.0001 7 0 0 0 0.00E+00 0.00E+00 - - - 0.6228 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20760.20760.2 0.0196 14-Sep K.EALLELLR[166.11].L sp|Q13895|BYST_HUMAN 1 965.5785 1.19 52900 20760 2 965.578837 483.7965 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3824 - 919840 - - - 0.3469 - 1.981 0.351 - 319.8 1 2 0 0.0003 8 0 0 0 3.25E+07 2.73E+07 - - - 3.6951 1 230117_WJC_METTL3_WT_vs_EV_F06.20763.20763.3 4.37E-07 15/60 R.TPEQVAEEEYLLQELR.K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1945.9633 -1 52903 20763 3 1945.964898 649.6617 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3824.4 - 725524 - - - 0.8279 - 2.755 0.537 - 297.9 1 2 0 0.0016 16 0 0 0 0.00E+00 0.00E+00 - - - 7.1269 1 230117_WJC_METTL3_WT_vs_EV_F06.20764.20764.3 2.36E-05 16/60 R.TPEQVAEEEYLLQELR[166.11].K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1955.9716 -1 52904 20764 3 1955.974474 652.9978 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3824.6 - 640451 - - - 1.4913 - 2.855 0.542 - 301.3 1 2 0 0.0029 16 0 0 0 0.00E+00 0.00E+00 - - - 7.2737 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20766.20766.2 0.0166 14-Aug K.EALLELLR.L sp|Q13895|BYST_HUMAN 1 955.5702 1.19 52906 20766 2 955.571069 478.7924 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3824.8 - 516263 - - - 0.8759 - 1.94 0.367 - 251.4 1 2 0 0.0008 8 0 0 0 3.25E+07 2.73E+07 - - - 3.75 1 230117_WJC_METTL3_WT_vs_EV_F06.20767.20767.2 2.76E-06 17/24 K.MVFINNIALAQIK[136.11].N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1481.852 1.19 52907 20767 2 1481.852489 741.9333 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3824.9 - 500408 - - - 0.3597 - 2.929 0.626 - 915.6 1 2 0 0.0005 13 0 0 0 9.19E+06 7.75E+06 - - - 6.4226 1 230117_WJC_METTL3_WT_vs_EV_F06.20768.20768.2 1.11E-06 15/24 K.MVFINNIALAQIK.N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1473.8378 1.19 52908 20768 2 1473.839355 737.9262 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3825.1 - 487441 - - - 1.0849 - 2.797 0.613 - 657.1 1 2 0 0.0016 13 0 0 0 9.19E+06 7.75E+06 - - - 6.2079 1 230117_WJC_METTL3_WT_vs_EV_F06.20770.20770.2 2.62E-05 18-Nov R.QALTDFLLAR[166.11].K "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1156.648 -1 52910 20770 2 1156.649524 579.3313 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.84 3825.4 - 462655 - - - 1.3366 - 2.379 0.444 - 421 1 2 0 0.0015 10 0 0 0 0.00E+00 0.00E+00 - - - 4.7391 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20771.20771.2 0.000424 18-Oct K.DLFDPIIEDR.H "sp|P12277|KCRB_HUMAN,tr|G3V461|G3V461_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 3 1231.6085 0.55 52911 20771 2 1231.608607 616.8115 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 3.84 3825.5 - 458203 - - - 0.1129 - 1.923 0.469 - 349.4 1 2 0 0.0001 10 0 0 0 1.63E+06 2.94E+06 - - - 4.3302 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.20780.20780.2 0.00809 20-Jun K.ELGIWEPLAVK.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1253.702 10.08 52919 20780 2 1253.703276 627.8583 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3826.4 - 5.45E+06 - - - 1.0385 - 1.202 0.335 - 108.7 1 2 0 0.0013 11 0 0 0 1.20E+09 1.19E+08 - - - 2.0126 1 230117_WJC_METTL3_WT_vs_EV_F06.20793.20793.2 2.16E-07 14/24 K.VLGTAFDPFLGGK.N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1320.7078 8.97 52930 20793 2 1320.709051 661.3612 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3827.6 - 1.35E+07 - - - 0.9563 - 2.389 0.585 - 463.4 1 2 0 0.0013 13 0 0 0 5.32E+08 5.93E+07 - - - 5.5965 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20795.20795.2 0.00399 20-Nov K.ELGIWEPLAVK[136.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1261.7162 10.08 52932 20795 2 1261.717181 631.8654 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3827.7 - 3.13E+06 - - - 0.7981 - 2.07 0.306 - 448.7 1 2 0 0.001 11 0 0 0 1.20E+09 1.19E+08 - - - 3.269 1 230117_WJC_METTL3_WT_vs_EV_F06.20796.20796.2 1.47E-08 15/24 K.VLGTAFDPFLGGK[136.11].N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1328.722 8.99 52933 20796 2 1328.722482 665.3683 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3827.8 - 1.46E+06 - - - 0.3718 - 2.761 0.617 - 514.8 1 2 0 0.0005 13 0 0 0 5.28E+08 5.87E+07 - - - 6.2046 1 230117_WJC_METTL3_WT_vs_EV_F06.20797.20797.2 0.00016 20-Dec R.QLLEEMLTSYR.L sp|O75688|PPM1B_HUMAN 1 1381.6912 0.45 52934 20797 2 1381.691228 691.8529 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3827.8 - 1.34E+06 - - - 0.055 - 2.509 0.531 - 729.1 1 2 0 0.0001 11 0 0 0 3.51E+07 7.79E+07 - - - 5.4514 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20798.20798.2 0.000888 20-Aug K.TLPLFYGSIVR[166.11].F "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1274.7262 1.17 52935 20798 2 1274.728587 638.3704 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 8.41 3827.9 - 814196 - - - 1.8498 - 1.696 0.394 - 248 1 2 0 0.0024 11 0 0 0 3.19E+07 2.71E+07 - - - 3.3794 1 230117_WJC_METTL3_WT_vs_EV_F06.20799.20799.2 6.88E-05 14/22 R.LALFNPDVC[160.03]WDR.N sp|O00483|NDUA4_HUMAN 1 1504.7133 2.8 52936 20799 2 1504.713747 753.3639 Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1 4.21 3828 - 751534 - - - 0.3077 - 2.706 0.412 - 793.3 1 2 0 0.0005 12 0 0 0 1.19E+07 4.25E+06 - - - 4.7031 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.20801.20801.2 0.0269 18-Sep K.EFLFNPYLTR[166.11].K "sp|P13378|HXD8_HUMAN,sp|P31273|HXC8_HUMAN,sp|P17481|HXB8_HUMAN,tr|I3L3R1|I3L3R1_HUMAN,tr|I3L383|I3L383_HUMAN,tr|A0A0A0MSX5|A0A0A0MSX5_HUMAN,tr|A0A0A0MTF4|A0A0A0MTF4_HUMAN" 7 1308.6742 1.97 52938 20801 2 1308.676836 655.3444 Homeobox protein Hox-D8 OS=Homo sapiens OX=9606 GN=HOXD8 PE=1 SV=2 6.1 3828.2 - 520749 - - - 2.0196 - 1.587 0.263 - 169.8 1 2 0 0.0026 10 0 0 0 1.21E+07 6.15E+06 - - - 2.2718 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20804.20804.2 2.27E-07 18-Oct K.GYGFVSFFNK.W "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN" 4 1164.5604 0.41 52941 20804 2 1164.562871 583.2875 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 8.59 3828.6 - 355778 - - - 2.1261 - 2.117 0.423 - 309.8 1 2 0 0.0025 10 0 0 0 7.62E+06 1.88E+07 - - - 4.258 1 230117_WJC_METTL3_WT_vs_EV_F06.20808.20808.2 3.76E-09 17/28 K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 0.77 52943 20808 2 1521.872868 761.945 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3829.2 - 3.15E+06 - - - -1.6716 - 3.289 0.625 - 838.3 1 2 0 -0.0025 15 0 0 0 1.10E+07 1.44E+07 - - - 6.5836 1 230117_WJC_METTL3_WT_vs_EV_F06.20809.20809.2 1.90E-06 15/26 K.LGLVGVNLTLDGVK.S "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 1396.829 1.21 52944 20809 2 1396.827333 699.4218 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 3829.3 - 2.27E+06 - - - -1.1691 - 3.023 0.568 - 885.7 1 2 0 -0.0016 14 0 0 0 1.38E+07 1.14E+07 - - - 6.0118 1 230117_WJC_METTL3_WT_vs_EV_F06.20810.20810.2 9.39E-08 19/28 K.TVAGQDAVIVLLGTR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1511.8671 0.77 52945 20810 2 1511.864693 756.9408 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3829.4 - 3.18E+06 - - - -1.6199 - 3.273 0.625 - 1088.4 1 2 0 -0.0024 15 0 0 0 1.10E+07 1.44E+07 - - - 6.5716 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.20811.20811.3 3.15E-07 20/56 K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 0.68 52946 20811 3 1521.873212 508.2991 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3829.5 - 2.39E+06 - - - -1.4456 - 2.705 0.497 - 648.2 1 2 0 -0.0022 15 0 0 0 6.46E+06 9.57E+06 - - - 6.677 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20812.20812.2 0.0127 20-Nov K.LLPAITILGC[160.03]R.V "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 2 1225.7217 2.84 52947 20812 2 1225.722673 613.8681 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 8.25 3829.7 - 1.98E+06 - - - 0.8232 - 2.105 0.404 - 411.9 1 2 0 0.001 11 0 0 0 1.58E+07 5.56E+06 - - - 4.0382 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.20813.20813.2 0.00508 13/24 K.ALVLANPEVSLWR.K "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 1466.8245 1.43 52948 20813 2 1466.822471 734.4196 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6.05 3829.8 - 1.89E+06 - - - -1.4167 - 2.309 0.366 - 571.6 1 2 0 -0.0021 13 0 0 0 8.86E+06 6.19E+06 - - - 3.8913 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.20814.20814.3 9.14E-05 21/56 K.TVAGQDAVIVLLGTR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1511.8671 0.68 52949 20814 3 1511.864825 504.963 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3829.9 - 1.83E+06 - - - -1.5325 - 3.311 0.507 - 676.7 1 2 0 -0.0023 15 0 0 0 6.46E+06 9.57E+06 - - - 7.316 1 230117_WJC_METTL3_WT_vs_EV_F06.20816.20816.2 9.51E-05 14/24 K.LLEQALVIEEQLR.R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1552.8825 1.32 52951 20816 2 1552.880253 777.4485 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3830.2 - 1.49E+06 - - - -1.4199 - 3.077 0.38 - 811.2 1 2 0 -0.0022 13 0 0 0 7.20E+06 5.45E+06 - - - 4.7317 1 230117_WJC_METTL3_WT_vs_EV_F06.20817.20817.2 7.40E-07 15/30 R.IASLPVEVQEVSLLDK.L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1738.9717 -1 52952 20817 2 1738.967329 870.4931 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.14 3830.3 - 1.41E+06 - - - -2.4946 - 2.697 0.577 - 563.3 1 2 0 -0.0043 16 0 0 0 0.00E+00 0.00E+00 - - - 5.7406 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.20819.20819.2 0.00209 14/24 K.ALVLANPEVSLWR[166.11].K "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 1476.8328 1.43 52954 20819 2 1476.831844 739.4237 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6.05 3830.6 - 1.13E+06 - - - -0.6602 - 2.641 0.391 - 781.1 1 2 0 -0.001 13 0 0 0 8.86E+06 6.19E+06 - - - 4.4211 1 230117_WJC_METTL3_WT_vs_EV_F06.20820.20820.2 1.61E-05 16/24 K.LLEQALVIEEQLR[166.11].R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1562.8907 1.34 52955 20820 2 1562.889713 782.4526 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3830.7 - 1.04E+06 - - - -0.6494 - 2.653 0.442 - 1220.1 1 2 0 -0.001 13 0 0 0 7.61E+06 5.68E+06 - - - 4.8094 0.8591 230117_WJC_METTL3_WT_vs_EV_F06.20824.20824.2 1.80E-05 16-Sep R.FYTLIPHDF.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1151.5651 - 52959 20824 2 1151.562123 576.7898 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.08 3831.2 - 739569 - - - -2.626 - 1.524 0.558 - 211 1 1 0 -0.003 9 0 0 0 - - - - - 4.3804 1 230117_WJC_METTL3_WT_vs_EV_F06.20827.20827.2 1.45E-06 15/28 R.LISEILSESVVPDVR.S "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 11 1654.9142 2.01 52962 20827 2 1654.909994 828.4644 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.14 3831.6 - 473751 - - - -2.5125 - 2.954 0.586 - 702.5 1 2 0 -0.0042 15 0 0 0 3.11E+06 1.55E+06 - - - 6.0309 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.20829.20829.2 0.0096 20-Oct R.QLLEEMLTSYR[166.11].L sp|O75688|PPM1B_HUMAN 1 1391.6994 0.45 52963 20829 2 1391.697346 696.857 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3831.9 - 1.83E+06 - - - -1.4917 - 2.159 0.419 - 424.4 1 2 0 -0.0021 11 0 0 0 3.51E+07 7.79E+07 - - - 4.2172 1 230117_WJC_METTL3_WT_vs_EV_F06.20831.20831.2 4.36E-05 13/22 K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 1.27 52965 20831 2 1314.791265 658.4028 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3832.1 - 1.91E+06 - - - 0.1072 - 2.352 0.509 - 564.2 1 2 0 0.0001 12 0 0 0 1.52E+08 1.20E+08 - - - 5.0508 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.20835.20835.2 0.0349 20-Oct K.VPPPWLIAMQR.Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1306.722 -1 52969 20835 2 1306.721605 654.3683 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3832.6 - 997973 - - - -0.3008 - 1.694 0.278 - 245.4 1 2 0 -0.0004 11 0 0 0 0.00E+00 0.00E+00 - - - 2.5201 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.20836.20836.2 0.0423 16-Sep R.YSFIQALVR.R sp|Q92621|NU205_HUMAN 1 1095.6077 1.77 52970 20836 2 1095.608128 548.8111 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 8.75 3832.8 - 901418 - - - 0.4089 - 1.743 0.352 - 292.8 1 2 0 0.0004 9 0 0 0 5.06E+06 2.86E+06 - - - 3.2481 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.20839.20839.2 0.0247 14-Aug R.QVLPFLLR.R "sp|O14981|BTAF1_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 2 984.612 1.29 52973 20839 2 984.611341 493.3133 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 9.75 3833.2 - 468830 - - - -0.7069 - 1.555 0.325 - 275.6 1 2 0 -0.0007 8 0 0 0 3.05E+06 2.37E+06 - - - 2.7727 1 230117_WJC_METTL3_WT_vs_EV_F06.20843.20843.2 2.94E-09 13/24 R.LGSTIFVANLDFK.V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1423.7711 1.86 52977 20843 2 1423.769989 712.8928 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3833.7 - 368855 - - - -0.7923 - 2.93 0.559 - 663.6 1 2 0 -0.0011 13 0 0 0 2.72E+07 1.46E+07 - - - 5.9284 0.997 230117_WJC_METTL3_WT_vs_EV_F06.20845.20845.2 0.118 14-Jul R.QVLPFLLR[166.11].R "sp|O14981|BTAF1_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 2 994.6203 1.29 52979 20845 2 994.619498 498.3174 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 9.75 3833.9 - 333677 - - - -0.8134 - 1.35 0.299 - 142.3 1 2 0 -0.0008 8 0 0 0 3.05E+06 2.37E+06 - - - 2.1543 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20850.20850.2 9.15E-05 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 4330.81 52983 20850 2 1603.764355 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3834.6 - 2.38E+08 - - - 0.2588 - 1.877 0.495 - 248.1 1 2 0 0.0004 12 0 0 0 2.55E+09 5.90E+05 - - - 4.3537 1 230117_WJC_METTL3_WT_vs_EV_F06.20861.20861.2 5.12E-08 24-Dec R.LGSTIFVANLDFK[136.11].V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1431.7853 1.89 52994 20861 2 1431.784468 716.8999 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3835.9 - 575185 - - - -0.593 - 2.766 0.537 - 650.2 1 2 0 -0.0008 13 0 0 0 2.72E+07 1.44E+07 - - - 5.6182 0.8548 230117_WJC_METTL3_WT_vs_EV_F06.20862.20862.2 0.937 20-Oct D.EAAAQALIGGR.D "sp|Q13087|PDIA2_HUMAN,tr|H0Y4J5|H0Y4J5_HUMAN" 2 1055.5724 1.29 52995 20862 2 1055.570081 528.7935 Protein disulfide-isomerase A2 OS=Homo sapiens OX=9606 GN=PDIA2 PE=1 SV=2 6.1 3836.1 - 403719 - - - -2.1562 - 2.184 0.341 - 240.8 1 1 0 -0.0023 11 0 0 0 3.17E+06 2.46E+06 - - - 3.6721 1 230117_WJC_METTL3_WT_vs_EV_F06.20865.20865.2 0.000979 26-Dec K.NLPIYSEEIVEMYK.G "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1726.8488 -1 52998 20865 2 1726.843529 864.4317 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3836.5 - 273488 - - - -3.0379 - 2.661 0.518 - 336 1 2 0 -0.0052 14 0 0 0 0.00E+00 0.00E+00 - - - 5.3213 0.9935 230117_WJC_METTL3_WT_vs_EV_F06.20871.20871.2 0.182 26-Aug K.LGLVGVNLTLDGVK[136.11].S "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 1404.8432 1.21 53003 20871 2 1404.843836 703.4289 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 3837.2 - 811706 - - - 0.4769 - 1.265 0.172 - 111.6 1 2 0 0.0007 14 0 0 0 1.38E+07 1.14E+07 - - - 0.9011 1 230117_WJC_METTL3_WT_vs_EV_F06.20873.20873.2 1.39E-05 22-Oct K.LVTLPVSFAQLK[136.11].N sp|Q96AG4|LRC59_HUMAN 1 1322.8053 1.27 53005 20873 2 1322.805672 662.4099 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3837.4 - 3.02E+07 - - - 0.2631 - 2.113 0.566 - 315.4 1 2 0 0.0003 12 0 0 0 1.52E+08 1.20E+08 - - - 5.1898 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.20875.20875.2 0.0249 16-Sep K.ITFLLQAIR[166.11].N "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1083.668 1.17 53007 20875 2 1083.668671 542.8413 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 3837.5 - 2.99E+06 - - - 0.6321 - 1.473 0.327 - 173.7 1 2 0 0.0007 9 0 0 0 1.34E+07 1.14E+07 - - - 2.5765 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.20876.20876.2 0.0216 16-Sep K.ITFLLQAIR.N "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1073.6597 -1 53008 20876 2 1073.660018 537.8371 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 3837.6 - 2.67E+06 - - - 0.2813 - 1.772 0.377 - 227.7 1 2 0 0.0003 9 0 0 0 0.00E+00 0.00E+00 - - - 3.4806 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20878.20878.2 0.0367 20-Dec K.VSVFFGGLSIK.K "sp|O00148|DX39A_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|A0A0D9SEM9|A0A0D9SEM9_HUMAN" 3 1152.6543 3.85 53010 20878 2 1152.65665 577.3344 ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2 8.72 3837.8 - 2.34E+06 - - - 2.0422 - 1.819 0.409 - 333.4 1 2 0 0.0024 11 0 0 0 7.87E+06 2.04E+06 - - - 3.6796 0.9998 230117_WJC_METTL3_WT_vs_EV_F06.20881.20881.3 0.00233 13/48 K.LLEQALVIEEQLR.R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1552.8825 2.16 53013 20881 3 1552.884129 518.6348 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3838.2 - 1.71E+06 - - - 1.0761 - 1.807 0.414 - 212.1 1 2 0 0.0017 13 0 0 0 2.63E+06 1.21E+06 - - - 4.7594 1 230117_WJC_METTL3_WT_vs_EV_F06.20883.20883.3 2.69E-09 Dec-56 R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 1.49 53015 20883 3 2001.974651 668.3319 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3838.5 - 1.42E+06 - - - 0.4585 - 2.638 0.554 - 189.4 1 2 0 0.0009 15 0 0 0 2.64E+06 1.78E+06 - - - 7.2474 0.9961 230117_WJC_METTL3_WT_vs_EV_F06.20886.20886.2 0.00102 20-Oct K.VSVFFGGLSIK[136.11].K "sp|O00148|DX39A_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|A0A0D9SEM9|A0A0D9SEM9_HUMAN" 3 1160.6685 -1 53018 20886 2 1160.675077 581.3415 ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2 8.72 3838.9 - 1.28E+06 - - - 5.67 - 2.003 0.388 - 258.9 1 2 0 0.0066 11 0 0 0 0.00E+00 0.00E+00 - - - 3.7839 1 230117_WJC_METTL3_WT_vs_EV_F06.20887.20887.2 8.50E-07 15/30 R.LPC[160.03]IYLVDSGGAYLPR.Q "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJW5|A0A804HJW5_HUMAN,tr|A0A0G2JM88|A0A0G2JM88_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HIH3|A0A804HIH3_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|D6RDF7|D6RDF7_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HJW2|A0A804HJW2_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|D6R9R1|D6R9R1_HUMAN,tr|A0A804HHS4|A0A804HHS4_HUMAN,tr|A0A0S2Z5R4|A0A0S2Z5R4_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 16 1792.9182 -1 53019 20887 2 1792.916397 897.4664 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.83 3839 - 1.14E+06 - - - -1.0012 - 2.987 0.636 - 696.4 1 2 0 -0.0018 16 0 0 0 0.00E+00 0.00E+00 - - - 6.4282 0.9998 230117_WJC_METTL3_WT_vs_EV_F06.20888.20888.3 0.000101 Oct-44 R.EGFLDTLVVLHR.A "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 1397.7667 1.38 53020 20888 3 1397.766946 466.9295 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.32 3839.1 - 804970 - - - 0.176 - 2.018 0.421 - 122.6 1 2 0 0.0002 12 0 0 0 1.95E+06 1.41E+06 - - - 5.1798 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.20892.20892.3 0.0523 Jun-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 -1 53023 20892 3 1603.765285 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3839.6 - 1.78E+06 - - - 0.8387 - 1.243 0.289 - 51.7 1 2 0 0.0013 12 0 0 0 0.00E+00 0.00E+00 - - - 2.3646 1 230117_WJC_METTL3_WT_vs_EV_F06.20893.20893.2 6.73E-07 18-Dec F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 -1 53024 20893 2 1343.611739 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3839.6 - 0 - - - 0.2062 - 2.489 0.574 - 510.6 1 1 0 0.0003 10 0 0 0 0.00E+00 0.00E+00 - - - 5.8258 1 230117_WJC_METTL3_WT_vs_EV_F06.20894.20894.2 2.94E-07 20-Oct K.VLYVYDMLAGK[136.11].L "sp|Q9Y5J1|UTP18_HUMAN,tr|J3KSR7|J3KSR7_HUMAN" 2 1278.6773 0.97 53025 20894 2 1278.684009 640.3459 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 5.8 3839.7 - 0 - - - 5.2109 - 2.094 0.493 - 301.1 1 2 0 0.0067 11 0 0 0 6.89E+06 7.11E+06 - - - 4.6796 0.9953 230117_WJC_METTL3_WT_vs_EV_F06.20897.20897.2 0.0201 14-Jun R.GFVFSLIK.S "sp|Q96N67|DOCK7_HUMAN,tr|A0A1B0GWE0|A0A1B0GWE0_HUMAN" 2 909.5324 2.2 53028 20897 2 909.531383 455.7735 Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4 8.75 3840.1 - 0 - - - -1.1072 - 1.185 0.32 - 93.8 1 2 0 -0.001 8 0 0 0 9.11E+05 4.14E+05 - - - 1.9161 1 230117_WJC_METTL3_WT_vs_EV_F06.20905.20905.2 1.26E-09 14/26 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.9 53034 20905 2 1669.895895 835.9552 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3841 - 4.69E+06 - - - -0.021 - 2.486 0.611 - 545.7 1 2 0 0 14 0 0 0 1.08E+08 1.20E+08 - - - 5.8391 1 230117_WJC_METTL3_WT_vs_EV_F06.20908.20908.2 4.75E-09 15/26 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.9 53037 20908 2 1661.88087 831.9481 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3841.3 - 3.77E+06 - - - -0.5175 - 2.679 0.645 - 614.5 1 2 0 -0.0009 14 0 0 0 1.08E+08 1.20E+08 - - - 6.2776 1 230117_WJC_METTL3_WT_vs_EV_F06.20909.20909.2 5.50E-05 18-Nov R.SDLVLLYELK.Q sp|Q9NPF5|DMAP1_HUMAN 1 1191.6751 1.36 53038 20909 2 1191.676252 596.8448 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.37 3841.4 - 1.40E+06 - - - 0.9743 - 2.451 0.507 - 403.1 1 2 0 0.0012 10 0 0 0 2.99E+07 2.20E+07 - - - 5.2877 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20910.20910.2 0.0106 18-Nov R.MALLATVLGR.F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1043.6161 2.22 53039 20910 2 1043.616633 522.8153 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.5 3841.6 - 951007 - - - 0.4762 - 2.216 0.448 - 509.1 1 2 0 0.0005 10 0 0 0 2.78E+07 1.26E+07 - - - 4.5708 1 230117_WJC_METTL3_WT_vs_EV_F06.20912.20912.2 0.000103 20-Dec K.VAVFFGGLSIK.K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1136.6594 0.88 53041 20912 2 1136.660928 569.337 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3841.8 - 901164 - - - 1.361 - 2.452 0.523 - 563.9 1 2 0 0.0015 11 0 0 0 2.08E+07 2.37E+07 - - - 5.3297 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.20915.20915.2 0.00142 12-Jun K.YFLWVVK.F sp|P62993|GRB2_HUMAN 1 953.5375 7.56 53044 20915 2 953.53701 477.776 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 8.59 3842.2 - 443501 - - - -0.4877 - 1.294 0.353 - 121.8 1 2 0 -0.0005 7 0 0 0 4.90E+06 6.48E+05 - - - 2.4648 0.9661 230117_WJC_METTL3_WT_vs_EV_F06.20927.20927.2 0.0035 14-Aug V.PEWVDTVK[136.11].L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 980.5058 1.16 53055 20927 2 980.508163 491.2602 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 3843.8 - 42579.2 - - - 2.362 - 1.956 0.375 - 174.7 1 1 0 0.0023 8 0 0 0 1.78E+06 1.54E+06 - - - 3.8334 0.9784 230117_WJC_METTL3_WT_vs_EV_F06.20933.20933.2 1.22 22-Aug K.DAGQISGLNVLR[166.11].V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1251.6811 7.6 53059 20933 2 1251.679371 626.8478 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 3844.5 - 2.59E+06 - - - -1.3574 - 1.402 0.116 - 134.4 1 2 0 -0.0017 12 0 0 0 4.45E+08 5.86E+07 - - - 0.7863 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.20934.20934.2 0.0783 14-Jul R.DFLLDIAR[166.11].Q "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 971.5316 1.52 53060 20934 2 971.532904 486.7731 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 3844.7 - 1.21E+06 - - - 1.3916 - 1.352 0.206 - 195.4 1 2 0 0.0014 8 0 0 0 3.03E+07 1.99E+07 - - - 1.4717 1 230117_WJC_METTL3_WT_vs_EV_F06.20936.20936.3 3.85E-07 14/52 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.91 53062 20936 3 1661.884066 554.9679 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3844.9 - 1.26E+06 - - - 1.4056 - 2.584 0.505 - 207.5 1 2 0 0.0023 14 0 0 0 1.27E+07 1.40E+07 - - - 6.6925 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20937.20937.2 8.27E-05 24-Nov R.VLLFTDDVALVSK.A "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1418.8021 1.71 53063 20937 2 1418.802368 710.4083 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.21 3845.1 - 490819 - - - 0.2016 - 2.261 0.46 - 277.1 1 2 0 0.0003 13 0 0 0 8.38E+06 4.89E+06 - - - 4.5323 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20938.20938.2 0.000521 18-Sep R.DFILPISDVR.A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|Q4VXM0|Q4VXM0_HUMAN,tr|Q4VXM1|Q4VXM1_HUMAN" 5 1173.6394 2.52 53064 20938 2 1173.640249 587.827 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.21 3845.2 - 442738 - - - 0.7455 - 2.043 0.424 - 314.9 1 2 0 0.0009 10 0 0 0 2.88E+07 1.15E+07 - - - 4.1666 1 230117_WJC_METTL3_WT_vs_EV_F06.20943.20943.2 0.000104 22-Dec K.TLQTISLLGYMK[136.11].H sp|O60264|SMCA5_HUMAN 1 1374.7672 0.91 53069 20943 2 1374.771833 688.3909 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 8.26 3845.8 - 203362 - - - 3.3526 - 2.41 0.523 - 463.7 1 2 0 0.0046 12 0 0 0 4.36E+06 4.79E+06 - - - 5.2169 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20944.20944.2 0.000143 22-Aug K.TLQTISLLGYMK.H sp|O60264|SMCA5_HUMAN 1 1366.753 0.77 53070 20944 2 1366.753133 684.3838 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 8.26 3846 - 188450 - - - 0.0798 - 1.752 0.478 - 157.3 1 2 0 0.0001 12 0 0 0 4.50E+06 5.87E+06 - - - 4.0469 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.20945.20945.2 0.000115 20-Jul R.WPDPEDLLTPR.W sp|Q8TAE8|G45IP_HUMAN 1 1337.6616 1.68 53071 20945 2 1337.657125 669.8381 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.03 3846.1 - 180252 - - - -3.32 - 1.792 0.459 - 169.2 1 2 0 -0.0044 11 0 0 0 1.81E+06 1.08E+06 - - - 4.0078 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.20952.20952.2 0.000391 20-Oct K.VAVFFGGLSIK[136.11].K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1144.6736 0.89 53077 20952 2 1144.673901 573.3441 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3847 - 1.29E+06 - - - 0.2796 - 1.965 0.461 - 313.2 1 2 0 0.0003 11 0 0 0 2.12E+07 2.39E+07 - - - 4.2732 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.20954.20954.2 3.17 16-Aug R.DLLFQALGR.T sp|Q9NSD9|SYFB_HUMAN 1 1031.5764 3.89 53079 20954 2 1031.579466 516.7955 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 5.84 3847.2 - 1.04E+06 - - - 2.9915 - 1.611 0.212 - 172 1 2 0 0.0031 9 0 0 0 3.02E+07 7.76E+06 - - - 1.9854 0.9998 230117_WJC_METTL3_WT_vs_EV_F06.20956.20956.3 0.00143 Nov-52 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.91 53081 20956 3 1669.897011 557.6393 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3847.4 - 870965 - - - 0.6473 - 1.936 0.379 - 130.8 1 2 0 0.0011 14 0 0 0 1.27E+07 1.40E+07 - - - 4.5208 0.8753 230117_WJC_METTL3_WT_vs_EV_F06.20957.20957.2 0.0213 14-Jun F.LFLWVTGR.A sp|Q86U44|MTA70_HUMAN 1 990.5651 999 53082 20957 2 990.567529 496.2898 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.75 3847.5 - 366668 - - - 2.4653 - 1.411 0.274 - 104.7 1 1 0 0.0024 8 0 0 0 7.47E+06 0.00E+00 - - - 2.1024 0.9944 230117_WJC_METTL3_WT_vs_EV_F06.20958.20958.2 0.11 18-Jun R.TYGVSFFLVK[136.11].E "sp|Q9Y4G6|TLN2_HUMAN,sp|Q9Y490|TLN1_HUMAN" 2 1167.6419 1.89 53083 20958 2 1167.643454 584.8282 Talin-2 OS=Homo sapiens OX=9606 GN=TLN2 PE=1 SV=4 8.26 3847.6 - 255080 - - - 1.2906 - 1.191 0.226 - 58.2 5 2 0 0.0015 10 0 0 0 7.33E+06 3.89E+06 - - - 0.8854 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.20971.20971.2 0.0393 20-Aug K.YNVEAVELLIR[166.11].N "sp|A5YKK6|CNOT1_HUMAN,tr|H3BMZ2|H3BMZ2_HUMAN" 2 1327.7375 5.31 53094 20971 2 1327.735228 664.876 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.53 3849.4 - 680612 - - - -1.7278 - 1.511 0.385 - 227.5 1 2 0 -0.0023 11 0 0 0 9.08E+06 1.71E+06 - - - 3.0005 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.20976.20976.2 0.00415 14-Aug R.DFLLDIAR.Q "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 961.5233 1.52 53098 20976 2 961.522503 481.7689 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 3850 - 2.22E+06 - - - -0.8102 - 1.644 0.352 - 297.6 1 2 0 -0.0008 8 0 0 0 3.04E+07 1.99E+07 - - - 3.14 1 230117_WJC_METTL3_WT_vs_EV_F06.20978.20978.2 0.000223 13/20 R.TSLGNVVLLLK.S "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1155.7227 2.02 53100 20978 2 1155.723119 578.8686 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 8.41 3850.2 - 672998 - - - 0.3539 - 2.626 0.422 - 438.4 1 2 0 0.0004 11 0 0 0 2.14E+07 1.06E+07 - - - 4.7696 1 230117_WJC_METTL3_WT_vs_EV_F06.20980.20980.2 1.46E-08 22-Nov K.ITAEEMYDIFGK.Y sp|Q9Y3B4|SF3B6_HUMAN 1 1415.6643 2.36 53102 20980 2 1415.663396 708.8394 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.14 3850.5 - 527153 - - - -0.616 - 2.479 0.636 - 447.1 1 2 0 -0.0009 12 0 0 0 8.37E+06 3.54E+06 - - - 6.1269 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.20982.20982.2 0.00318 14-Jul R.TLFGFLGK[136.11].L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 889.5153 1.5 53104 20982 2 889.514749 445.7649 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3850.8 - 305086 - - - -0.6082 - 1.245 0.414 - 143.5 1 2 0 -0.0005 8 0 0 0 4.93E+07 3.27E+07 - - - 2.7595 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.20983.20983.2 0.000532 24-Dec K.AAILPTSIFLTNK[136.11].K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1395.8217 0.48 53105 20983 2 1395.821198 698.9181 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3850.9 - 298271 - - - -0.3611 - 1.893 0.388 - 372.5 1 2 0 -0.0005 13 0 0 0 5.11E+07 1.07E+08 - - - 3.5445 1 230117_WJC_METTL3_WT_vs_EV_F06.20984.20984.2 6.66E-08 22-Oct K.ITAEEMYDIFGK[136.11].Y sp|Q9Y3B4|SF3B6_HUMAN 1 1423.6785 2.36 53106 20984 2 1423.677358 712.8465 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.14 3851 - 260681 - - - -0.7797 - 2.317 0.611 - 338.9 1 2 0 -0.0011 12 0 0 0 8.37E+06 3.54E+06 - - - 5.7644 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.20985.20985.3 0.00336 Aug-36 K.YRPLFDYFLK.C "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 1360.718 1.63 53107 20985 3 1360.717074 454.5799 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.5 3851.1 - 255485 - - - -0.6504 - 1.683 0.319 - 82.3 1 2 0 -0.0009 10 0 0 0 4.31E+06 2.65E+06 - - - 3.6166 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.20986.20986.2 0.0022 20-Nov R.FDEISFVNFAR[166.11].G sp|Q08945|SSRP1_HUMAN 1 1353.6593 0.79 53108 20986 2 1353.656154 677.8369 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3851.3 - 245297 - - - -2.3026 - 2.397 0.411 - 497.9 1 2 0 -0.0031 11 0 0 0 1.18E+07 1.50E+07 - - - 4.4406 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20991.20991.2 0.00324 24-Nov K.AAILPTSIFLTNK.K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1387.8075 0.48 53113 20991 2 1387.810093 694.911 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3851.9 - 116735 - - - 1.867 - 2.159 0.396 - 326.4 1 2 0 0.0026 13 0 0 0 5.10E+07 1.07E+08 - - - 3.9404 0.9935 230117_WJC_METTL3_WT_vs_EV_F06.20996.20996.2 0.136 14-Jul R.TLFGFLGK.L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 881.5011 1.08 53117 20996 2 881.500389 441.7578 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3852.4 - 1.35E+06 - - - -0.7952 - 1.026 0.315 - 137.8 1 2 0 -0.0007 8 0 0 0 5.08E+07 4.70E+07 - - - 1.4448 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.20998.20998.2 0.000103 18-Oct R.TMYLLGYIPK.D "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1197.6468 1.32 53119 20998 2 1197.648323 599.8307 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 8.17 3852.6 - 1.25E+06 - - - 1.2984 - 1.793 0.501 - 354.1 1 2 0 0.0016 10 0 0 0 7.01E+06 5.33E+06 - - - 4.3707 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21008.21008.2 0.000238 20-Dec R.FDEISFVNFAR.G sp|Q08945|SSRP1_HUMAN 1 1343.651 0.79 53126 21008 2 1343.65237 672.8328 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3853.8 - 289243 - - - 1.0189 - 1.753 0.491 - 286.7 1 2 0 0.0014 11 0 0 0 1.18E+07 1.50E+07 - - - 4.1856 0.9866 230117_WJC_METTL3_WT_vs_EV_F06.21022.21022.2 0.0893 14-Jun R.VFLWGSFR[166.11].D "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1020.5421 1.01 53138 21022 2 1020.541285 511.2783 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 9.72 3855.3 - 439949 - - - -0.7565 - 1.35 0.124 - 173.9 1 2 0 -0.0008 8 0 0 0 1.11E+07 1.10E+07 - - - 0.8617 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.21023.21023.2 0.103 16-Jul R.DIVQFVPFR[166.11].E "sp|Q96FN4|CPNE2_HUMAN,sp|O75131|CPNE3_HUMAN,sp|O95741|CPNE6_HUMAN,sp|Q86YQ8|CPNE8_HUMAN,sp|Q8IYJ1|CPNE9_HUMAN,sp|Q9UBL6|CPNE7_HUMAN,sp|Q9HCH3|CPNE5_HUMAN,sp|Q96A23|CPNE4_HUMAN,tr|E7ENV7|E7ENV7_HUMAN" 9 1129.616 2.87 53139 21023 2 1129.617591 565.8153 Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3 5.84 3855.4 - 314744 - - - 1.4527 - 1.599 0.312 - 225.8 1 2 0 0.0016 9 0 0 0 1.29E+07 4.50E+06 - - - 2.7029 1 230117_WJC_METTL3_WT_vs_EV_F06.21035.21035.2 3.93E-07 13/26 K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 14.79 53149 21035 2 1613.805718 807.9078 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3856.9 - 63513.2 - - - 2.864 - 2.215 0.547 - 346.2 1 2 0 0.0046 14 0 0 0 9.14E+08 6.18E+07 - - - 5.0753 1 230117_WJC_METTL3_WT_vs_EV_F06.21036.21036.2 4.96E-07 13/20 R.PLEVFMC[160.03]SVLK[136.11].R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1329.6916 4.64 53150 21036 2 1329.689151 665.8531 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.38 3857 - 0 - - - -1.8538 - 2.536 0.551 - 523.5 1 1 0 -0.0025 11 0 0 0 3.53E+07 7.61E+06 - - - 5.6274 0.9969 230117_WJC_METTL3_WT_vs_EV_F06.21037.21037.2 0.000189 14/24 K.IAVPLIQGYTVLR[166.11].L sp|Q8IW92|GLBL2_HUMAN 1 1451.874 0.87 53151 21037 2 1451.88225 726.9443 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3857.1 - 61273.9 - - - 5.7126 - 2.381 0.422 - 672.3 1 2 0 0.0083 13 0 0 0 7.30E+06 8.39E+06 - - - 4.3818 1 230117_WJC_METTL3_WT_vs_EV_F06.21038.21038.2 4.94E-07 24-Nov R.VIYAMAEDGLLFK[136.11].F "sp|P30825|SL7A1_HUMAN,sp|P52569|CTR2_HUMAN,tr|A0A1W2PR06|A0A1W2PR06_HUMAN" 3 1476.7778 4.24 53152 21038 2 1476.777221 739.3962 High affinity cationic amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A1 PE=1 SV=1 4.37 3857.2 - 0 - - - -0.3839 - 2.395 0.645 - 297 1 2 0 -0.0006 13 0 0 0 1.05E+07 2.47E+06 - - - 6.0464 1 230117_WJC_METTL3_WT_vs_EV_F06.21039.21039.2 8.24E-09 24-Dec R.VIYAMAEDGLLFK.F "sp|P30825|SL7A1_HUMAN,sp|P52569|CTR2_HUMAN,tr|A0A1W2PR06|A0A1W2PR06_HUMAN" 3 1468.7636 4.32 53153 21039 2 1468.766145 735.3891 High affinity cationic amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A1 PE=1 SV=1 4.37 3857.4 - 0 - - - 1.7409 - 2.709 0.6 - 371.2 1 2 0 0.0026 13 0 0 0 1.05E+07 2.42E+06 - - - 6.0295 1 230117_WJC_METTL3_WT_vs_EV_F06.21044.21044.2 1.26E-05 13/20 R.PLEVFMC[160.03]SVLK.R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1321.6774 4.81 53156 21044 2 1321.673487 661.846 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.38 3857.9 - 2.53E+06 - - - -2.9727 - 2.437 0.587 - 590.2 1 1 0 -0.0039 11 0 0 0 3.66E+07 7.61E+06 - - - 5.7851 0.8864 230117_WJC_METTL3_WT_vs_EV_F06.21048.21048.2 0.00406 18-Sep R.ILDSAEFIKF.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1181.6332 1.56 53160 21048 2 1181.631901 591.8239 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3858.3 - 905204 - - - -1.1213 - 1.683 0.352 - 126.8 1 1 0 -0.0013 10 0 0 0 9.62E+06 6.16E+06 - - - 3.0935 0.9896 230117_WJC_METTL3_WT_vs_EV_F06.21049.21049.2 0.000129 16-Sep K.YPENFFLLR.G "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|C9J9S3|C9J9S3_HUMAN,tr|E7ETD8|E7ETD8_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 12 1197.6182 2.94 53161 21049 2 1197.612255 599.8164 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 6 3858.4 - 737006 - - - -5.0016 - 1.916 0.421 - 344.4 1 2 0 -0.006 9 0 0 0 4.78E+06 1.63E+06 - - - 4.0298 1 230117_WJC_METTL3_WT_vs_EV_F06.21056.21056.3 1.18E-08 14/52 K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 15.41 53166 21056 3 1613.800882 538.941 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3859.4 - 742385 - - - -0.1326 - 2.778 0.548 - 287 1 2 0 -0.0002 14 0 0 0 2.63E+08 1.71E+07 - - - 7.3649 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21057.21057.2 0.000709 13/20 K.LEDVLPLAFTR.L "sp|Q5SSJ5|HP1B3_HUMAN,tr|B0QZK4|B0QZK4_HUMAN,tr|Q5SWC8|Q5SWC8_HUMAN" 3 1272.7078 0.88 53167 21057 2 1272.708535 637.3612 Heterochromatin protein 1-binding protein 3 OS=Homo sapiens OX=9606 GN=HP1BP3 PE=1 SV=1 4.37 3859.5 - 519858 - - - 0.5869 - 2.442 0.332 - 621.8 1 2 0 0.0007 11 0 0 0 1.05E+07 1.19E+07 - - - 3.9082 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.21058.21058.2 0.00131 24-Oct K.LIHIPINNIIVGG.- sp|P60059|SC61G_HUMAN 1 1371.8238 - 53168 21058 2 1371.827368 686.9192 Protein transport protein Sec61 subunit gamma OS=Homo sapiens OX=9606 GN=SEC61G PE=1 SV=1 6.74 3859.7 - 432255 - - - 2.5856 - 2.398 0.364 - 360.6 1 2 0 0.0035 13 0 0 0 - - - - - 3.9732 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.21060.21060.2 0.00233 20-Oct R.ILEFIAVSQLR.G "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN,tr|K7ER27|K7ER27_HUMAN" 4 1287.7551 0.91 53170 21060 2 1287.754177 644.8848 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 6 3859.9 - 293029 - - - -0.6958 - 2.223 0.425 - 364.7 1 2 0 -0.0009 11 0 0 0 4.22E+06 4.63E+06 - - - 4.3409 1 230117_WJC_METTL3_WT_vs_EV_F06.21061.21061.2 1.46E-08 13/26 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 3.8 53171 21061 2 1535.790269 768.9025 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3860.1 - 275844 - - - -0.1712 - 2.454 0.533 - 497 1 2 0 -0.0003 14 0 0 0 7.02E+07 1.85E+07 - - - 5.2304 0.9925 230117_WJC_METTL3_WT_vs_EV_F06.21066.21066.2 0.0298 24-Oct R.IQLYDNDIYFIPR.N sp|Q6PCB5|RSBNL_HUMAN 1 1668.8512 -1 53176 21066 2 1668.845213 835.4329 Lysine-specific demethylase RSBN1L OS=Homo sapiens OX=9606 GN=RSBN1L PE=1 SV=2 4.21 3860.7 - 113520 - - - -3.5623 - 1.902 0.325 - 195.7 1 2 0 -0.0059 13 0 0 0 0.00E+00 0.00E+00 - - - 3.0896 1 230117_WJC_METTL3_WT_vs_EV_F06.21069.21069.2 2.45E-07 13/30 R.VIFLEDDDVAAVVDGR[166.11].L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1741.8762 -1 53179 21069 2 1741.873077 871.9454 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 3.71 3861.1 - 91460.9 - - - -1.7929 - 2.996 0.648 - 493.5 1 2 0 -0.0031 16 0 0 0 0.00E+00 0.00E+00 - - - 6.5239 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21073.21073.3 1.25E-06 13/52 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 4.71 53183 21073 3 1535.789694 512.9375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3861.6 - 71766 - - - -0.5456 - 2.372 0.506 - 298.3 1 2 0 -0.0008 14 0 0 0 1.77E+07 3.76E+06 - - - 6.4766 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.21074.21074.3 0.279 Sep-48 K.AAILPTSIFLTNK.K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1387.8075 0.02 53184 21074 3 1387.807572 463.6098 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3861.8 - 66665.3 - - - 0.0504 - 1.387 0.274 - 74.7 1 2 0 0.0001 13 0 0 0 1.16E+06 4.94E+07 - - - 2.4818 1 230117_WJC_METTL3_WT_vs_EV_F06.21076.21076.2 5.10E-06 22-Dec K.TLGVDLVALATR.V "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1227.7187 2.16 53185 21076 2 1227.719128 614.8666 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.5 3862 - 1.14E+07 - - - 0.3592 - 2.213 0.547 - 391.9 1 2 0 0.0004 12 0 0 0 3.41E+07 1.58E+07 - - - 5.1711 1 230117_WJC_METTL3_WT_vs_EV_F06.21077.21077.2 2.04E-06 28-Nov K.VILESEVIAEAVGVK.K sp|O15226|NKRF_HUMAN 1 1554.8869 1.18 53186 21077 2 1554.88911 778.4507 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.25 3862 - 2.20E+06 - - - 1.4374 - 2.53 0.612 - 278.8 1 2 0 0.0022 15 0 0 0 1.41E+07 1.20E+07 - - - 5.8426 1 230117_WJC_METTL3_WT_vs_EV_F06.21078.21078.2 0.000333 22-Dec K.TLGVDLVALATR[166.11].V "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1237.727 4.75 53187 21078 2 1237.728595 619.8708 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.5 3862.1 - 5.50E+06 - - - 1.3234 - 2.423 0.488 - 393 1 2 0 0.0016 12 0 0 0 8.19E+07 1.72E+07 - - - 4.9735 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21080.21080.2 3.50E-07 26-Oct K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 14.76 53189 21080 2 1621.819544 811.9149 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3862.2 - 3.16E+06 - - - 2.6193 - 1.903 0.517 - 208 1 2 0 0.0042 14 0 0 0 9.12E+08 6.18E+07 - - - 4.4729 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.21081.21081.2 0.000756 22-Sep R.LGLQNDLFSLAR.A "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1345.7354 1.59 53190 21081 2 1345.737235 673.875 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.84 3862.2 - 2.07E+06 - - - 1.3636 - 1.545 0.363 - 182.4 1 2 0 0.0018 12 0 0 0 6.08E+06 3.82E+06 - - - 2.8662 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21082.21082.3 0.221 Dec-44 R.LLALLDALASHK.A "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 1263.7551 -1 53191 21082 3 1263.754878 422.259 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6.74 3862.3 - 1.82E+06 - - - -0.1543 - 2.733 0.287 - 272 1 2 0 -0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 4.5265 1 230117_WJC_METTL3_WT_vs_EV_F06.21083.21083.2 5.76E-06 13/26 K.TFAPEEISAMVLTK[136.11].M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1543.8047 3.8 53192 21083 2 1543.804477 772.9096 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3862.3 - 1.81E+06 - - - -0.1652 - 2.16 0.543 - 431.6 1 2 0 -0.0003 14 0 0 0 7.02E+07 1.85E+07 - - - 4.9841 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.21084.21084.2 6.31E-05 20-Nov K.DFPLSGYVELR.Y sp|O75489|NDUS3_HUMAN 1 1294.6558 1.54 53193 21084 2 1294.655801 648.3352 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 4.37 3862.4 - 1.79E+06 - - - 0.0378 - 1.937 0.4 - 482.4 1 2 0 0 11 0 0 0 8.67E+06 5.64E+06 - - - 3.7839 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21085.21085.3 0.000588 13/44 R.LLALLDALASHK[136.11].A "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 1271.7693 -1 53194 21085 3 1271.769624 424.9304 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6.74 3862.4 - 1.61E+06 - - - 0.276 - 2.56 0.483 - 281.5 1 2 0 0.0004 12 0 0 0 0.00E+00 0.00E+00 - - - 6.5304 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21087.21087.2 1.26E-06 22-Dec R.LGLQNDLFSLAR[166.11].A "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1355.7437 1.59 53196 21087 2 1355.743659 678.8791 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.84 3862.5 - 1.31E+06 - - - -0.0081 - 2.473 0.378 - 610.5 1 2 0 0 12 0 0 0 6.08E+06 3.82E+06 - - - 4.2153 1 230117_WJC_METTL3_WT_vs_EV_F06.21090.21090.2 1.03E-05 13/28 K.VILESEVIAEAVGVK[136.11].K sp|O15226|NKRF_HUMAN 1 1562.9011 1.18 53199 21090 2 1562.898864 782.4578 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.25 3862.7 - 1.02E+06 - - - -1.4147 - 2.598 0.574 - 339.6 1 2 0 -0.0022 15 0 0 0 1.41E+07 1.20E+07 - - - 5.6271 1 230117_WJC_METTL3_WT_vs_EV_F06.21092.21092.2 1.32E-07 26-Dec K.LFIYNPTTGEFLGR.T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1626.8406 1.44 53201 21092 2 1626.839327 814.4276 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3862.9 - 866142 - - - -0.7782 - 2.295 0.546 - 446 1 2 0 -0.0013 14 0 0 0 3.74E+07 2.59E+07 - - - 5.158 1 230117_WJC_METTL3_WT_vs_EV_F06.21097.21097.2 3.00E-06 18-Nov R.WYEWLDPSIK.K sp|Q99459|CDC5L_HUMAN 1 1335.6499 1.64 53204 21097 2 1335.650963 668.8322 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3863.5 - 726286 - - - 0.7667 - 2.033 0.496 - 415.1 1 2 0 0.001 10 0 0 0 2.08E+07 1.27E+07 - - - 4.6846 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.21098.21098.2 0.0444 14-Jul R.IPFTFWAR.Y sp|Q9Y5V3|MAGD1_HUMAN 1 1036.5494 0.5 53205 21098 2 1036.55098 519.282 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 9.75 3863.6 - 102978 - - - 1.4886 - 1.418 0.356 - 179.5 1 2 0 0.0015 8 0 0 0 7.20E+06 1.43E+07 - - - 2.7232 1 230117_WJC_METTL3_WT_vs_EV_F06.21099.21099.2 2.05E-10 18/28 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 3.31 53206 21099 2 1700.896684 851.4565 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3863.8 - 1.36E+06 - - - -1.0688 - 3.758 0.632 - 889.6 1 2 0 -0.0018 15 0 0 0 3.65E+08 1.10E+08 - - - 6.9632 1 230117_WJC_METTL3_WT_vs_EV_F06.21104.21104.2 4.92E-07 19/28 R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 -1 53211 21104 2 1710.902896 856.4607 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3864.4 - 547684 - - - -2.2655 - 3.568 0.552 - 1034.9 1 2 0 -0.0039 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2441 1 230117_WJC_METTL3_WT_vs_EV_F06.21110.21110.2 9.60E-07 17/28 K.VSALDLAVLDQVEAR.L "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 6 1597.8675 -1 53217 21110 2 1597.878446 799.941 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.03 3865.2 - 261050 - - - 6.8279 - 3.493 0.525 - 1112 1 2 0 0.0109 15 0 0 0 0.00E+00 0.00E+00 - - - 5.9903 1 230117_WJC_METTL3_WT_vs_EV_F06.21111.21111.2 3.34E-07 15/22 R.LEGLTDEINFLR.Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1418.7405 1.7 53218 21111 2 1418.739669 710.3775 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3865.4 - 251363 - - - -0.6174 - 2.834 0.568 - 838.3 1 2 0 -0.0009 12 0 0 0 3.85E+07 2.26E+07 - - - 5.9768 1 230117_WJC_METTL3_WT_vs_EV_F06.21112.21112.3 5.31E-09 22/56 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 5.89 53219 21112 3 1700.896616 567.9734 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3865.5 - 189793 - - - -1.1088 - 3.396 0.599 - 757.5 1 2 0 -0.0019 15 0 0 0 7.72E+07 1.31E+07 - - - 8.4079 0.998 230117_WJC_METTL3_WT_vs_EV_F06.21113.21113.2 0.000463 24-Oct R.GLAFELVYSPAIK.D "sp|P78346|RPP30_HUMAN,tr|Q5VU11|Q5VU11_HUMAN,tr|Q5VU10|Q5VU10_HUMAN" 3 1406.781 2.06 53220 21113 2 1406.78697 704.3978 Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1 6 3865.6 - 187463 - - - 4.2771 - 1.863 0.358 - 275.1 1 2 0 0.006 13 0 0 0 1.95E+06 9.44E+05 - - - 3.2802 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.21120.21120.2 0.000394 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 53226 21120 2 1603.76328 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3866.3 - 2.44E+08 - - - -0.4115 - 1.642 0.49 - 251 1 2 0 -0.0007 12 0 0 0 6.44E+09 0.00E+00 - - - 3.9648 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.21122.21122.2 0.00199 18-Oct K.FEELNMDLFR.S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1312.6122 -1 53228 21122 2 1312.610677 657.3134 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.14 3866.4 - 1.74E+07 - - - -1.1397 - 2.129 0.417 - 360.7 1 2 0 -0.0015 10 0 0 0 0.00E+00 0.00E+00 - - - 4.2297 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.21123.21123.2 0.000166 20-Dec K.SGAYLIPLLER.L "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1230.6972 1.27 53229 21123 2 1230.696395 616.3559 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.72 3866.5 - 1.46E+07 - - - -0.6728 - 2.241 0.368 - 548.6 1 2 0 -0.0008 11 0 0 0 1.28E+08 1.01E+08 - - - 3.9417 1 230117_WJC_METTL3_WT_vs_EV_F06.21124.21124.2 0.000306 22-Nov R.LEGLTDEINFLR[166.11].Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1428.7488 1.7 53230 21124 2 1428.746294 715.3817 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3866.5 - 1.42E+07 - - - -1.7645 - 2.637 0.483 - 572.9 1 2 0 -0.0025 12 0 0 0 3.85E+07 2.26E+07 - - - 5.1589 0.9982 230117_WJC_METTL3_WT_vs_EV_F06.21125.21125.2 3.96E-05 26-Nov K.LFIYNPTTGEFLGR[166.11].T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1636.8489 1.44 53231 21125 2 1636.845467 819.4317 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3866.6 - 1.40E+07 - - - -2.0747 - 1.727 0.478 - 263.4 1 2 0 -0.0034 14 0 0 0 3.74E+07 2.59E+07 - - - 3.9416 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.21126.21126.2 1.16E-05 20-Nov K.SGAYLIPLLER[166.11].L "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1240.7055 1.27 53232 21126 2 1240.705464 621.36 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.72 3866.6 - 1.27E+07 - - - -0.0234 - 2.025 0.322 - 384.8 1 2 0 0 11 0 0 0 1.28E+08 1.01E+08 - - - 3.328 1 230117_WJC_METTL3_WT_vs_EV_F06.21127.21127.3 1.18E-07 14/52 K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 15.24 53233 21127 3 1621.81037 541.6124 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3866.7 - 9.48E+06 - - - -3.0373 - 2.721 0.572 - 281 1 2 0 -0.0049 14 0 0 0 2.63E+08 1.73E+07 - - - 7.5761 1 230117_WJC_METTL3_WT_vs_EV_F06.21128.21128.2 0.000163 13/26 R.VLLATLSIPITPER.T sp|Q14152|EIF3A_HUMAN 1 1521.913 0.96 53234 21128 2 1521.91086 761.9638 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3866.7 - 7.76E+06 - - - -1.4258 - 2.723 0.459 - 350 1 2 0 -0.0022 14 0 0 0 3.06E+07 3.18E+07 - - - 4.9443 1 230117_WJC_METTL3_WT_vs_EV_F06.21129.21129.2 1.97E-08 17/26 R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 14.05 53235 21129 2 1581.806548 791.9109 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3866.8 - 6.91E+06 - - - -0.44 - 3.219 0.65 - 760.3 1 2 0 -0.0007 14 0 0 0 1.89E+07 1.34E+06 - - - 6.7754 1 230117_WJC_METTL3_WT_vs_EV_F06.21130.21130.2 2.83E-06 18-Sep R.YVLGMQELFR.G "sp|Q96J01|THOC3_HUMAN,tr|D6RGZ2|D6RGZ2_HUMAN" 2 1254.6431 -1 53236 21130 2 1254.634745 628.3288 THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1 6 3866.9 - 5.72E+06 - - - -6.6425 - 1.859 0.564 - 238.8 1 2 0 -0.0083 10 0 0 0 0.00E+00 0.00E+00 - - - 4.9348 1 230117_WJC_METTL3_WT_vs_EV_F06.21131.21131.2 4.18E-05 16-Oct R.IIFVDEVFK[136.11].L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1116.631 -1 53237 21131 2 1116.62897 559.3228 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 4.37 3867 - 5.32E+06 - - - -1.861 - 2.064 0.476 - 244.9 1 2 0 -0.0021 9 0 0 0 0.00E+00 0.00E+00 - - - 4.6525 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.21132.21132.2 0.0069 18-Oct K.FSLFAGGMLR.V sp|Q9BVK6|TMED9_HUMAN 1 1097.5692 -1 53238 21132 2 1097.566422 549.7919 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 9.75 3867 - 5.04E+06 - - - -2.5183 - 1.779 0.34 - 339.3 1 2 0 -0.0028 10 0 0 0 0.00E+00 0.00E+00 - - - 3.1593 0.998 230117_WJC_METTL3_WT_vs_EV_F06.21134.21134.2 4.40E-05 20-Dec R.GVTFLFPIQAK.T sp|Q9NR30|DDX21_HUMAN 1 1219.6965 0.65 53240 21134 2 1219.694338 610.8555 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3867.2 - 4.56E+06 - - - -1.7685 - 2.262 0.292 - 559.7 1 2 0 -0.0022 11 0 0 0 4.43E+07 6.79E+07 - - - 3.4052 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.21135.21135.2 0.00117 14-Sep K.FYSFLVLK.K "sp|Q9H4I0|RD21L_HUMAN,sp|O60216|RAD21_HUMAN,tr|A0A804HJ87|A0A804HJ87_HUMAN,tr|E5RI01|E5RI01_HUMAN,tr|E5RG18|E5RG18_HUMAN,tr|E5RFZ5|E5RFZ5_HUMAN" 6 1015.5743 -1 53241 21135 2 1015.573735 508.7944 Double-strand-break repair protein rad21-like protein 1 OS=Homo sapiens OX=9606 GN=RAD21L1 PE=2 SV=3 8.59 3867.3 - 4.38E+06 - - - -0.512 - 1.673 0.422 - 200.5 1 2 0 -0.0005 8 0 0 0 0.00E+00 0.00E+00 - - - 3.7098 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.21139.21139.2 0.00229 22-Nov R.VTGVPLSYLLSR.G "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1303.75 1.87 53244 21139 2 1303.748361 652.8823 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.72 3867.8 - 545282 - - - -1.2472 - 1.833 0.368 - 273.7 1 2 0 -0.0016 12 0 0 0 7.01E+06 3.75E+06 - - - 3.3529 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.21140.21140.2 0.00213 14-Sep R.FPLFGGWK.T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 950.5014 1.58 53245 21140 2 950.499497 476.258 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3867.8 - 1.51E+06 - - - -2.0274 - 1.662 0.315 - 325.7 1 2 0 -0.0019 8 0 0 0 1.37E+07 8.68E+06 - - - 2.8992 1 230117_WJC_METTL3_WT_vs_EV_F06.21141.21141.2 1.19E-07 16/26 R.VLLATLSIPITPER[166.11].T sp|Q14152|EIF3A_HUMAN 1 1531.9213 0.96 53246 21141 2 1531.92069 766.9679 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3867.9 - 5.75E+06 - - - -0.3982 - 2.922 0.468 - 736.6 1 2 0 -0.0006 14 0 0 0 3.06E+07 3.18E+07 - - - 5.1883 1 230117_WJC_METTL3_WT_vs_EV_F06.21142.21142.2 2.18E-06 15/24 R.LLSFSPEEFPTLK.A sp|Q5JSZ5|PRC2B_HUMAN 1 1506.797 1.46 53247 21142 2 1506.796877 754.4058 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3868 - 2.62E+06 - - - -0.0796 - 2.516 0.544 - 762.6 1 2 0 -0.0001 13 0 0 0 2.52E+07 1.72E+07 - - - 5.427 0.999 230117_WJC_METTL3_WT_vs_EV_F06.21143.21143.2 0.00243 14/24 R.LLSFSPEEFPTLK[136.11].A sp|Q5JSZ5|PRC2B_HUMAN 1 1514.8112 1.46 53248 21143 2 1514.817164 758.4129 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3868.2 - 2.17E+06 - - - 3.9391 - 2.213 0.423 - 508 1 2 0 0.006 13 0 0 0 2.52E+07 1.72E+07 - - - 4.2021 1 230117_WJC_METTL3_WT_vs_EV_F06.21144.21144.2 0.00363 13/20 K.LSDLDYMQFIR.L sp|P82933|RT09_HUMAN 1 1399.6806 -1 53249 21144 2 1399.678827 700.8476 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.21 3868.3 - 1.85E+06 - - - -1.2574 - 2.936 0.406 - 1018 1 2 0 -0.0018 11 0 0 0 0.00E+00 0.00E+00 - - - 4.9528 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.21146.21146.2 0.000603 20-Nov K.LSDLDYMQFIR[166.11].L sp|P82933|RT09_HUMAN 1 1409.6889 -1 53251 21146 2 1409.687493 705.8517 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.21 3868.6 - 1.60E+06 - - - -0.9676 - 2.57 0.341 - 623.7 1 2 0 -0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 4.1127 1 230117_WJC_METTL3_WT_vs_EV_F06.21147.21147.2 1.95E-07 15/24 R.APLPDLYPFGTMR.G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1476.7435 1.88 53252 21147 2 1476.742825 739.379 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3868.7 - 1.31E+06 - - - -0.472 - 2.135 0.539 - 602.4 1 2 0 -0.0007 13 0 0 0 8.84E+06 4.70E+06 - - - 4.9685 0.999 230117_WJC_METTL3_WT_vs_EV_F06.21148.21148.2 0.000132 14-Aug R.GFVFITFK[136.11].E "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 965.5466 1.04 53253 21148 2 965.545507 483.7806 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3868.8 - 1.26E+06 - - - -1.1216 - 1.602 0.455 - 274.5 1 2 0 -0.0011 8 0 0 0 1.04E+07 1.00E+07 - - - 3.8226 1 230117_WJC_METTL3_WT_vs_EV_F06.21149.21149.2 1.98E-07 15/24 R.ELPTAFDYVEFTR[166.11].S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1596.7699 -1 53254 21149 2 1596.772274 799.3922 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.14 3868.9 - 859368 - - - 1.4592 - 2.801 0.629 - 989.7 1 2 0 0.0023 13 0 0 0 0.00E+00 0.00E+00 - - - 6.3295 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21151.21151.2 7.80E-06 14/24 R.APLPDLYPFGTMR[166.11].G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1486.7518 1.87 53256 21151 2 1486.755371 744.3832 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3869.2 - 801427 - - - 2.4073 - 2.024 0.431 - 615.8 1 2 0 0.0036 13 0 0 0 8.81E+06 4.70E+06 - - - 4.0328 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21152.21152.2 8.10E-05 26-Nov R.ILGIPVIVTEQYPK.G "sp|Q96CN7|ISOC1_HUMAN,tr|D6RGE2|D6RGE2_HUMAN" 2 1568.9178 -1 53257 21152 2 1568.92059 785.4662 Isochorismatase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ISOC1 PE=1 SV=3 6 3869.3 - 733327 - - - 1.7904 - 1.913 0.475 - 281.4 1 2 0 0.0028 14 0 0 0 0.00E+00 0.00E+00 - - - 4.1763 0.9998 230117_WJC_METTL3_WT_vs_EV_F06.21155.21155.3 0.000138 Oct-52 R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 15.49 53260 21155 3 1581.807263 528.2764 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3869.7 - 542716 - - - 0.012 - 2.257 0.373 - 175 1 2 0 0 14 0 0 0 3.26E+06 2.10E+05 - - - 4.8619 1 230117_WJC_METTL3_WT_vs_EV_F06.21157.21157.2 2.78E-08 28-Dec K.LLMSEDYFTQAMEVK.A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1803.8423 -1 53262 21157 2 1803.835151 902.9284 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.14 3870 - 416826 - - - -3.9682 - 2.576 0.595 - 299 1 2 0 -0.0072 15 0 0 0 0.00E+00 0.00E+00 - - - 5.7598 1 230117_WJC_METTL3_WT_vs_EV_F06.21158.21158.2 1.82E-07 28-Sep K.LLMSEDYFTQAMEVK[136.11].A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1811.8565 -1 53263 21158 2 1811.851911 906.9355 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.14 3870.1 - 390387 - - - -2.5377 - 2.208 0.543 - 182.4 1 2 0 -0.0046 15 0 0 0 0.00E+00 0.00E+00 - - - 4.9975 1 230117_WJC_METTL3_WT_vs_EV_F06.21160.21160.3 3.50E-07 14/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 11702.53 53264 21160 3 1603.765302 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3870.3 - 7.59E+06 - - - 0.8493 - 2.51 0.632 - 302 1 2 0 0.0014 12 0 0 0 6.03E+08 5.15E+04 - - - 8.1367 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.21163.21163.2 0.00127 16-Jul K.TTPLLSFLK[136.11].N sp|Q9BZI7|REN3B_HUMAN 1 1026.6205 0.97 53267 21163 2 1026.620927 514.3175 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 8.41 3870.5 - 8.05E+06 - - - 0.4325 - 1.591 0.382 - 208.3 1 2 0 0.0004 9 0 0 0 2.24E+07 2.32E+07 - - - 3.2057 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.21164.21164.2 0.111 26-Jul R.DYGVLLEGSGLALR.G sp|P30048|PRDX3_HUMAN 1 1461.7827 -1 53268 21164 2 1461.786657 731.8986 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 4.37 3870.5 - 6.47E+06 - - - 2.6769 - 1.774 0.347 - 167.5 1 2 0 0.0039 14 0 0 0 0.00E+00 0.00E+00 - - - 3.0412 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21165.21165.2 0.000527 18-Nov R.LLEVYDQLFK.S "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1266.686 2.24 53269 21165 2 1266.686608 634.3503 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3870.6 - 3.91E+06 - - - 0.4879 - 2.31 0.419 - 415.3 1 2 0 0.0006 10 0 0 0 1.26E+07 5.65E+06 - - - 4.4726 1 230117_WJC_METTL3_WT_vs_EV_F06.21167.21167.2 0.000491 16/26 R.DYGVLLEGSGLALR[166.11].G sp|P30048|PRDX3_HUMAN 1 1471.791 1.97 53271 21167 2 1471.790438 736.9028 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 4.37 3870.7 - 2.73E+06 - - - -0.3914 - 3.166 0.53 - 914.2 1 2 0 -0.0006 14 0 0 0 1.16E+07 5.91E+06 - - - 5.8475 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.21168.21168.2 0.0103 20-Oct K.NVPGLAILLSK.D sp|Q9BUL9|RPP25_HUMAN 1 1123.6965 1.12 53272 21168 2 1123.697131 562.8555 Ribonuclease P protein subunit p25 OS=Homo sapiens OX=9606 GN=RPP25 PE=1 SV=1 8.75 3870.8 - 2.54E+06 - - - 0.566 - 1.801 0.349 - 265.5 1 2 0 0.0006 11 0 0 0 6.27E+06 5.60E+06 - - - 3.2101 0.8539 230117_WJC_METTL3_WT_vs_EV_F06.21170.21170.2 0.0294 22-May R.DYLHLPPEIVPA.T "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1362.7184 - 53274 21170 2 1362.717891 682.3665 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.35 3870.9 - 2.25E+06 - - - -0.339 - 1.278 0.34 - 61.4 1 1 0 -0.0005 12 0 0 0 - - - - - 2.1975 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21171.21171.2 0.0796 20-Sep K.NVPGLAILLSK[136.11].D sp|Q9BUL9|RPP25_HUMAN 1 1131.7107 1.12 53275 21171 2 1131.711736 566.8626 Ribonuclease P protein subunit p25 OS=Homo sapiens OX=9606 GN=RPP25 PE=1 SV=1 8.75 3871 - 2.20E+06 - - - 0.9198 - 1.762 0.408 - 192.6 1 2 0 0.001 11 0 0 0 6.27E+06 5.58E+06 - - - 3.5865 1 230117_WJC_METTL3_WT_vs_EV_F06.21174.21174.2 5.25E-08 13/26 R.ILSVQGTEPLVLFK.E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1542.9021 -1 53278 21174 2 1542.904443 772.4583 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3871.2 - 1.73E+06 - - - 1.4985 - 2.525 0.604 - 584.9 1 2 0 0.0023 14 0 0 0 0.00E+00 0.00E+00 - - - 5.8258 1 230117_WJC_METTL3_WT_vs_EV_F06.21176.21176.2 5.45E-06 26-Nov R.ILSVQGTEPLVLFK[136.11].E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1550.9163 1.28 53280 21176 2 1550.919193 776.4654 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3871.4 - 1.65E+06 - - - 1.8454 - 2.316 0.545 - 361.3 1 2 0 0.0029 14 0 0 0 9.80E+06 7.67E+06 - - - 5.173 1 230117_WJC_METTL3_WT_vs_EV_F06.21178.21178.2 6.17E-10 22-Dec K.VMEETLSYLLGR.K "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN,tr|A0A5F9ZH78|A0A5F9ZH78_HUMAN" 3 1409.7225 22.05 53282 21178 2 1409.729218 705.8685 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 4.53 3871.5 - 1.60E+06 - - - 4.7995 - 2.439 0.634 - 541.2 1 2 0 0.0068 12 0 0 0 4.93E+06 2.23E+05 - - - 6.0675 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.21179.21179.2 0.000435 22-Sep K.LTAYAMTIPFVR.Q "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1381.7428 -1 53283 21179 2 1381.743303 691.8787 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 3871.6 - 1.59E+06 - - - 0.3691 - 2.076 0.365 - 340.2 1 2 0 0.0005 12 0 0 0 0.00E+00 0.00E+00 - - - 3.6586 1 230117_WJC_METTL3_WT_vs_EV_F06.21181.21181.3 1.23E-05 Oct-40 R.SIIGMIDMFHK.Y "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1290.6464 61.13 53284 21181 3 1290.647348 431.2228 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.46 3871.8 - 717815 - - - 0.6958 - 1.973 0.545 - 103.2 1 2 0 0.0009 11 0 0 0 6.61E+06 1.08E+05 - - - 6.5465 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21182.21182.2 0.00721 16-Aug K.AFVPAILFK.D sp|Q9HAU5|RENT2_HUMAN 1 1004.6059 1.13 53285 21182 2 1004.606706 503.3102 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3871.9 - 1.48E+06 - - - 0.8133 - 1.63 0.419 - 212.4 1 2 0 0.0008 9 0 0 0 7.16E+06 6.33E+06 - - - 3.549 1 230117_WJC_METTL3_WT_vs_EV_F06.21183.21183.2 9.46E-05 13/24 R.ELYAFFGDSLATR.F sp|Q9Y6J9|TAF6L_HUMAN 1 1488.7249 -1 53286 21183 2 1488.72233 745.3697 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4.37 3872 - 1.55E+06 - - - -1.723 - 2.381 0.558 - 571 1 2 0 -0.0026 13 0 0 0 0.00E+00 0.00E+00 - - - 5.3881 0.9945 230117_WJC_METTL3_WT_vs_EV_F06.21184.21184.2 0.00026 14-Sep R.FPLFGGWK[136.11].T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 958.5156 1.78 53287 21184 2 958.512236 480.2651 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3872.1 - 1.42E+06 - - - -3.5346 - 1.667 0.399 - 281.5 1 2 0 -0.0034 8 0 0 0 7.78E+06 4.37E+06 - - - 3.5282 0.9553 230117_WJC_METTL3_WT_vs_EV_F06.21187.21187.2 2.95E-05 20-Oct R.WPDPEDLLTPR[166.11].W sp|Q8TAE8|G45IP_HUMAN 1 1347.6698 -1 53290 21187 2 1347.661376 674.8422 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.03 3872.5 - 601359 - - - -6.2775 - 2.016 0.268 - 338.8 1 2 0 -0.0085 11 0 0 0 0.00E+00 0.00E+00 - - - 2.9145 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21188.21188.2 0.000244 13/26 K.TGAAGAEALSLLLK.R "sp|Q9P2N6|KANL3_HUMAN,tr|C9J5A4|C9J5A4_HUMAN,tr|A0A590UJ53|A0A590UJ53_HUMAN" 3 1313.7555 5.26 53291 21188 2 1313.756844 657.885 KAT8 regulatory NSL complex subunit 3 OS=Homo sapiens OX=9606 GN=KANSL3 PE=1 SV=2 5.66 3872.7 - 536676 - - - 1.0481 - 2.332 0.428 - 479.1 1 2 0 0.0014 14 0 0 0 5.15E+06 9.80E+05 - - - 4.3266 0.9508 230117_WJC_METTL3_WT_vs_EV_F06.21193.21193.2 4.07 18-Jun K.EPFNLFYIEK.D sp|Q08554|DSC1_HUMAN 1 1298.6547 -1 53296 21193 2 1298.653694 650.3346 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.53 3873.3 - 330734 - - - -0.7669 - 1.035 0.11 - 104.2 1 2 0 -0.001 10 0 0 0 0.00E+00 0.00E+00 - - - -0.0508 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.21194.21194.2 0.00319 22-Sep R.FGLLPLSMTSTR.K "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN,tr|J3QLT5|J3QLT5_HUMAN,tr|J3QKY9|J3QKY9_HUMAN" 5 1321.7064 0.54 53297 21194 2 1321.704715 661.8605 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 9.75 3873.4 - 323351 - - - -1.2809 - 1.771 0.379 - 240.6 1 2 0 -0.0017 12 0 0 0 1.72E+06 3.18E+06 - - - 3.3436 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.21195.21195.2 0.0426 16-Sep R.WLGDLILSK.S "sp|O75530|EED_HUMAN,tr|A0A5F9ZI63|A0A5F9ZI63_HUMAN" 2 1043.6015 1.24 53298 21195 2 1043.603863 522.808 Polycomb protein EED OS=Homo sapiens OX=9606 GN=EED PE=1 SV=2 5.84 3873.6 - 294808 - - - 2.2336 - 1.51 0.308 - 284.2 1 2 0 0.0023 9 0 0 0 4.78E+06 3.84E+06 - - - 2.5074 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.21203.21203.2 0.000165 16-Aug K.AFVPAILFK[136.11].D sp|Q9HAU5|RENT2_HUMAN 1 1012.6201 1.13 53305 21203 2 1012.624239 507.3173 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3874.7 - 1.28E+06 - - - 4.0983 - 1.616 0.475 - 211.5 1 2 0 0.0042 9 0 0 0 7.16E+06 6.33E+06 - - - 3.9366 1 230117_WJC_METTL3_WT_vs_EV_F06.21206.21206.2 5.64E-06 18-Oct R.AEVWDLDMLR.S sp|Q6P2E9|EDC4_HUMAN 1 1246.6016 1.21 53308 21206 2 1246.605681 624.3081 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 4.03 3875.1 - 704131 - - - 3.2673 - 2.236 0.487 - 544.3 1 2 0 0.0041 10 0 0 0 2.74E+06 2.27E+06 - - - 4.8828 1 230117_WJC_METTL3_WT_vs_EV_F06.21212.21212.2 2.98E-05 20/26 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.46 53314 21212 2 1672.883938 837.4479 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3875.9 - 238596 - - - 1.6212 - 3.405 0.584 - 1827.9 1 2 0 0.0027 14 0 0 0 2.97E+07 6.53E+07 - - - 6.4283 1 230117_WJC_METTL3_WT_vs_EV_F06.21214.21214.2 2.85E-05 22-Oct R.LIMNYLVTEGFK[136.11].E sp|Q9NWU2|GID8_HUMAN 1 1434.7672 0.99 53316 21214 2 1434.772539 718.3909 Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1 6 3876.2 - 221253 - - - 3.7044 - 2.057 0.589 - 225.3 1 2 0 0.0053 12 0 0 0 5.79E+06 5.83E+06 - - - 5.2874 1 230117_WJC_METTL3_WT_vs_EV_F06.21226.21226.2 1.48E-07 18/26 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.46 53327 21226 2 1662.87414 832.4438 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3877.2 - 1.85E+06 - - - 0.712 - 3.245 0.587 - 1394.3 1 2 0 0.0012 14 0 0 0 2.97E+07 6.53E+07 - - - 6.3301 1 230117_WJC_METTL3_WT_vs_EV_F06.21227.21227.2 6.76E-10 13/24 R.FGQDIISPLLSVK[136.11].E "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V414|A0A7I2V414_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|J3KNG4|J3KNG4_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|G3V5F3|G3V5F3_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|A0A7I2V4B9|A0A7I2V4B9_HUMAN,tr|H0YJY1|H0YJY1_HUMAN,tr|H0YJS6|H0YJS6_HUMAN,tr|G3V363|G3V363_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2V5R9|A0A7I2V5R9_HUMAN,tr|G3V4I1|G3V4I1_HUMAN,tr|A0A7I2V3Y3|A0A7I2V3Y3_HUMAN" 24 1423.8166 1.55 53328 21227 2 1423.819282 712.9156 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 5.84 3877.3 - 1.60E+06 - - - 1.8717 - 2.605 0.639 - 666.4 1 2 0 0.0027 13 0 0 0 1.25E+07 8.05E+06 - - - 6.2171 0.998 230117_WJC_METTL3_WT_vs_EV_F06.21231.21231.2 0.00353 22-Oct R.GLFIIDPNGVIK.H sp|P30048|PRDX3_HUMAN 1 1284.7442 2.15 53332 21231 2 1284.750011 643.3794 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3877.6 - 371334 - - - 4.5433 - 1.861 0.392 - 234.5 1 2 0 0.0058 12 0 0 0 3.81E+07 1.77E+07 - - - 3.5687 1 230117_WJC_METTL3_WT_vs_EV_F06.21232.21232.2 2.33E-11 15/30 R.LFVGNLPADITEDEFK.R sp|P23246|SFPQ_HUMAN 1 1806.904 -1 53333 21232 2 1806.908474 904.4593 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3877.7 - 300958 - - - 2.4866 - 3.132 0.6 - 390.9 1 2 0 0.0045 16 0 0 0 0.00E+00 0.00E+00 - - - 6.278 1 230117_WJC_METTL3_WT_vs_EV_F06.21234.21234.2 5.03E-08 30-Dec R.LFVGNLPADITEDEFK[136.11].R sp|P23246|SFPQ_HUMAN 1 1814.9182 1 53335 21234 2 1814.921088 908.4664 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3878 - 250019 - - - 1.6017 - 2.74 0.574 - 204.2 1 2 0 0.0029 16 0 0 0 1.16E+06 1.16E+06 - - - 5.7578 1 230117_WJC_METTL3_WT_vs_EV_F06.21238.21238.3 2.30E-06 17/52 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.68 53338 21238 3 1672.883116 558.6344 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3878.6 - 5.90E+06 - - - 1.1298 - 3.088 0.56 - 530.1 1 2 0 0.0019 14 0 0 0 2.20E+07 3.26E+07 - - - 7.7794 1 230117_WJC_METTL3_WT_vs_EV_F06.21240.21240.2 7.15E-07 17/26 K.LFSLELVDESGEIR[166.11].A sp|P27694|RFA1_HUMAN 1 1615.8333 0.13 53340 21240 2 1615.834091 808.9239 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4 3878.8 - 2.12E+06 - - - 0.5062 - 3.044 0.551 - 1209.6 1 2 0 0.0008 14 0 0 0 3.48E+06 2.76E+07 - - - 5.9039 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21242.21242.2 4.96E-05 18-Oct K.DAITQALFLR.E sp|Q9UNX4|WDR3_HUMAN 1 1146.6397 1.17 53342 21242 2 1146.641311 574.3271 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.84 3879.1 - 779648 - - - 1.398 - 2.182 0.436 - 276.6 1 2 0 0.0016 10 0 0 0 1.70E+07 1.45E+07 - - - 4.4387 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.21243.21243.2 0.000883 13/22 R.GLFIIDPNGVIK[136.11].H sp|P30048|PRDX3_HUMAN 1 1292.7584 2.15 53343 21243 2 1292.760974 647.3865 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3879.2 - 477220 - - - 2.0112 - 2.224 0.314 - 415.1 1 2 0 0.0026 12 0 0 0 3.81E+07 1.77E+07 - - - 3.4625 1 230117_WJC_METTL3_WT_vs_EV_F06.21245.21245.2 0.000629 13/24 K.DAAIYLVTSLASK.A sp|P55060|XPO2_HUMAN 1 1350.7395 1.14 53345 21245 2 1350.743709 676.377 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.83 3879.5 - 422396 - - - 3.1294 - 2.584 0.476 - 525.4 1 2 0 0.0042 13 0 0 0 6.01E+06 5.28E+06 - - - 4.9919 1 230117_WJC_METTL3_WT_vs_EV_F06.21249.21249.2 2.02E-05 26-Nov R.SAAQMEVASFLLSK.E sp|Q12834|CDC20_HUMAN 1 1480.7596 5.69 53349 21249 2 1480.762998 741.3871 Cell division cycle protein 20 homolog OS=Homo sapiens OX=9606 GN=CDC20 PE=1 SV=2 5.72 3880 - 290943 - - - 2.3177 - 2.402 0.483 - 400.3 1 2 0 0.0034 14 0 0 0 1.53E+06 2.69E+05 - - - 4.8064 1 230117_WJC_METTL3_WT_vs_EV_F06.21259.21259.2 0.000193 13/20 K.TITAYFGDLIR[166.11].R sp|Q96RS0|TGS1_HUMAN 1 1278.6848 1.72 53358 21259 2 1278.689913 640.3497 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 5.5 3881.2 - 936392 - - - 4.0315 - 2.308 0.547 - 486.8 1 2 0 0.0052 11 0 0 0 6.85E+06 3.97E+06 - - - 5.3421 0.8725 230117_WJC_METTL3_WT_vs_EV_F06.21265.21265.2 0.146 24-Jul L.REVTYFSLWYYNK.Q "sp|Q16825|PTN21_HUMAN,tr|G3V3S6|G3V3S6_HUMAN" 2 1767.8621 999 53364 21265 2 1767.861517 884.9383 Tyrosine-protein phosphatase non-receptor type 21 OS=Homo sapiens OX=9606 GN=PTPN21 PE=1 SV=2 8.43 3881.9 - 1.10E+06 - - - -0.3055 - 1.745 0.253 - 95.2 1 1 0 -0.0005 13 0 0 0 8.82E+06 0.00E+00 - - - 2.3384 0.9924 230117_WJC_METTL3_WT_vs_EV_F06.21268.21268.2 0.0533 Jul-32 R.ASSGGGAGGAAGYAPVK.Y sp|P25067|CO8A2_HUMAN 1 1376.6684 2.37 53367 21268 2 1376.66737 689.3415 Collagen alpha-2(VIII) chain OS=Homo sapiens OX=9606 GN=COL8A2 PE=1 SV=2 8.63 3882.3 - 515879 - - - -0.7787 - 1.315 0.217 - 80.9 1 2 0 -0.0011 17 0 0 0 2.46E+06 1.04E+06 - - - 1.3167 1 230117_WJC_METTL3_WT_vs_EV_F06.21275.21275.2 3.09E-05 13/26 R.YAIQLITAASLVC[160.03]R.K sp|Q9Y230|RUVB2_HUMAN 1 1577.8599 -1 53374 21275 2 1577.863474 789.9373 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 8.22 3883.2 - 281495 - - - 2.234 - 2.503 0.537 - 452.4 1 2 0 0.0035 14 0 0 0 0.00E+00 0.00E+00 - - - 5.3086 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.21276.21276.2 0.00137 18-Aug K.VFFNILEEAR[166.11].E "sp|Q9Y276|BCS1_HUMAN,tr|C9J1S9|C9J1S9_HUMAN,tr|C9J8G3|C9J8G3_HUMAN" 3 1246.6585 0.34 53375 21276 2 1246.659306 624.3365 Mitochondrial chaperone BCS1 OS=Homo sapiens OX=9606 GN=BCS1L PE=1 SV=1 4.53 3883.3 - 270153 - - - 0.612 - 1.385 0.294 - 190.8 1 2 0 0.0008 10 0 0 0 6.04E+05 1.77E+06 - - - 2.1214 1 230117_WJC_METTL3_WT_vs_EV_F06.21277.21277.2 1.05E-08 18/32 R.LWVGGLGPNTSLAALAR.E sp|Q8NDT2|RB15B_HUMAN 1 1694.9468 -1 53376 21277 2 1694.950276 848.4807 Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3 9.75 3883.5 - 245757 - - - 2.0567 - 3.239 0.624 - 807.3 1 2 0 0.0035 17 0 0 0 0.00E+00 0.00E+00 - - - 6.5382 1 230117_WJC_METTL3_WT_vs_EV_F06.21283.21283.2 6.51E-05 20-Nov K.LLTQYILNLGK.Y sp|O00203|AP3B1_HUMAN 1 1274.7598 1.44 53381 21283 2 1274.763784 638.3872 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 8.59 3884.2 - 3.72E+06 - - - 3.1065 - 2.258 0.492 - 437.4 1 2 0 0.004 11 0 0 0 7.45E+06 5.18E+06 - - - 4.877 1 230117_WJC_METTL3_WT_vs_EV_F06.21284.21284.2 0.0283 13/24 K.NVLIVEDIIDTGK.T sp|P00492|HPRT_HUMAN 1 1427.7872 1.75 53382 21284 2 1427.790081 714.9009 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.03 3884.3 - 3.19E+06 - - - 2.0451 - 2.406 0.523 - 506.4 1 2 0 0.0029 13 0 0 0 6.15E+06 3.51E+06 - - - 5.1563 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.21287.21287.2 0.0786 14-Sep M.VLDLDLFR[166.11].V "sp|P49591|SYSC_HUMAN,tr|Q5T5C7|Q5T5C7_HUMAN" 2 999.5629 0.65 53385 21287 2 999.565177 500.7887 "Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3" 4.21 3884.6 - 2.26E+06 - - - 2.326 - 1.789 0.261 - 330.6 1 2 0 0.0023 8 0 0 0 2.88E+06 4.41E+06 - - - 2.7223 1 230117_WJC_METTL3_WT_vs_EV_F06.21288.21288.2 2.46E-06 24-Dec K.NVLIVEDIIDTGK[136.11].T sp|P00492|HPRT_HUMAN 1 1435.8014 -1 53386 21288 2 1435.804122 718.908 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.03 3884.8 - 1.60E+06 - - - 1.923 - 2.562 0.443 - 430 1 2 0 0.0028 13 0 0 0 0.00E+00 0.00E+00 - - - 4.7267 1 230117_WJC_METTL3_WT_vs_EV_F06.21289.21289.2 2.39E-09 21/34 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.86 53387 21289 2 1936.014336 969.0131 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3884.9 - 1.56E+06 - - - 1.4189 - 4.242 0.624 - 1238.2 1 2 0 0.0027 18 0 0 0 2.08E+07 2.43E+07 - - - 7.2017 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.21290.21290.2 0.0951 16-Aug K.NIIIALIDR.L sp|Q96QK1|VPS35_HUMAN 1 1039.639 2.05 53388 21290 2 1039.642016 520.8268 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 5.84 3885 - 1.24E+06 - - - 2.9202 - 1.723 0.271 - 222.2 1 2 0 0.003 9 0 0 0 2.13E+06 1.04E+06 - - - 2.6157 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.21291.21291.2 0.0274 24-Aug R.FGQDIISPLLSVK.E "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V414|A0A7I2V414_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|J3KNG4|J3KNG4_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|G3V5F3|G3V5F3_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|A0A7I2V4B9|A0A7I2V4B9_HUMAN,tr|H0YJY1|H0YJY1_HUMAN,tr|H0YJS6|H0YJS6_HUMAN,tr|G3V363|G3V363_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2V5R9|A0A7I2V5R9_HUMAN,tr|G3V4I1|G3V4I1_HUMAN,tr|A0A7I2V3Y3|A0A7I2V3Y3_HUMAN" 24 1415.8024 1.6 53389 21291 2 1415.805424 708.9085 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 5.84 3885.1 - 1.21E+06 - - - 2.1239 - 1.22 0.223 - 145.9 1 2 0 0.003 13 0 0 0 1.29E+07 8.05E+06 - - - 1.1975 1 230117_WJC_METTL3_WT_vs_EV_F06.21292.21292.2 8.19E-17 22/34 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.86 53390 21292 2 1926.007432 964.0089 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3885.3 - 1.21E+06 - - - 2.1355 - 4.407 0.694 - 1536.3 1 2 0 0.0041 18 0 0 0 2.08E+07 2.43E+07 - - - 7.8121 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.21293.21293.2 0.0258 16-Oct K.SLDIYSFIK.E "sp|Q9NR50|EI2BG_HUMAN,tr|H0Y580|H0Y580_HUMAN" 2 1084.5805 0.76 53391 21293 2 1084.583713 543.2975 Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens OX=9606 GN=EIF2B3 PE=1 SV=1 5.55 3885.4 - 1.16E+06 - - - 2.9975 - 1.734 0.347 - 277.4 1 2 0 0.0033 9 0 0 0 4.96E+06 6.54E+06 - - - 3.1953 0.999 230117_WJC_METTL3_WT_vs_EV_F06.21294.21294.2 9.27E-05 20-Oct K.VLAISDLVIYR.T "sp|Q9HBF4|ZFYV1_HUMAN,tr|G3V5N8|G3V5N8_HUMAN" 2 1260.7442 1.65 53392 21294 2 1260.74912 631.3794 Zinc finger FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZFYVE1 PE=1 SV=1 5.81 3885.5 - 1.12E+06 - - - 3.9231 - 2.214 0.408 - 369.8 1 2 0 0.0049 11 0 0 0 2.32E+06 1.40E+06 - - - 4.2031 0.974 230117_WJC_METTL3_WT_vs_EV_F06.21295.21295.2 5.07E-06 22-Nov S.ILTIEDGIFEVK.S "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1375.7599 -1 53393 21295 2 1375.763038 688.8872 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3885.7 - 1.11E+06 - - - 2.2933 - 2.215 0.44 - 396.3 1 1 0 0.0032 12 0 0 0 0.00E+00 0.00E+00 - - - 4.3823 0.9934 230117_WJC_METTL3_WT_vs_EV_F06.21296.21296.2 0.00231 14-Aug R.FLTWILNR.Y sp|O43776|SYNC_HUMAN 1 1061.6022 1.2 53394 21296 2 1061.60827 531.8084 "Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1" 9.75 3885.8 - 1.05E+06 - - - 5.7168 - 1.684 0.326 - 227.6 1 2 0 0.0061 8 0 0 0 2.75E+06 2.29E+06 - - - 3.0188 1 230117_WJC_METTL3_WT_vs_EV_F06.21298.21298.2 3.70E-07 13/26 Y.LLNPDGLFTDYYGR.S sp|O43819|SCO2_HUMAN 1 1642.7991 4.07 53396 21298 2 1642.801838 822.4068 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 4.21 3886 - 854508 - - - 1.6533 - 2.207 0.567 - 434.8 1 1 0 0.0027 14 0 0 0 2.10E+06 5.16E+05 - - - 5.2146 0.9942 230117_WJC_METTL3_WT_vs_EV_F06.21299.21299.2 0.0109 16-Aug K.IPALDLLIK.L "sp|P78527|PRKDC_HUMAN,tr|F5GX40|F5GX40_HUMAN" 2 994.6427 -1 53397 21299 2 994.646924 498.3286 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 3886.2 - 682320 - - - 4.2779 - 1.564 0.235 - 124.1 1 2 0 0.0043 9 0 0 0 0.00E+00 0.00E+00 - - - 2.0693 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.21301.21301.3 0.00171 Aug-52 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.68 53398 21301 3 1662.878865 555.2983 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3886.4 - 251955 - - - 3.5535 - 1.789 0.289 - 72.2 1 2 0 0.0059 14 0 0 0 2.20E+07 3.26E+07 - - - 3.3062 1 230117_WJC_METTL3_WT_vs_EV_F06.21304.21304.3 2.15E-09 27/68 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.83 53401 21304 3 1936.020738 646.3445 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3886.7 - 3.08E+06 - - - 4.7257 - 3.385 0.666 - 763.8 1 2 0 0.0091 18 0 0 0 1.69E+07 2.04E+07 - - - 8.999 1 230117_WJC_METTL3_WT_vs_EV_F06.21305.21305.2 9.89E-08 15/26 K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.76 53402 21305 2 1651.934946 826.9731 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3886.8 - 2.48E+06 - - - 1.9971 - 2.712 0.573 - 679.8 1 2 0 0.0033 14 0 0 0 6.91E+07 9.05E+07 - - - 5.7758 1 230117_WJC_METTL3_WT_vs_EV_F06.21306.21306.2 3.95E-09 15/26 K.LYTLVTYVPVTTFK.N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1643.9174 0.76 53403 21306 2 1643.921918 822.966 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3886.9 - 1.46E+06 - - - 2.7197 - 2.631 0.596 - 754.8 1 2 0 0.0045 14 0 0 0 6.91E+07 9.05E+07 - - - 5.8692 0.9905 230117_WJC_METTL3_WT_vs_EV_F06.21307.21307.2 0.769 16-Jul K.SLDIYSFIK[136.11].E "sp|Q9NR50|EI2BG_HUMAN,tr|H0Y580|H0Y580_HUMAN" 2 1092.5947 0.74 53404 21307 2 1092.599159 547.3046 Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens OX=9606 GN=EIF2B3 PE=1 SV=1 5.55 3887.1 - 1.02E+06 - - - 4.1159 - 1.567 0.16 - 117.1 1 2 0 0.0045 9 0 0 0 4.84E+06 6.52E+06 - - - 1.5208 1 230117_WJC_METTL3_WT_vs_EV_F06.21308.21308.2 3.94E-08 18-Nov R.VYNALVAFIR.A sp|Q9BW92|SYTM_HUMAN 1 1164.6655 0.94 53405 21308 2 1164.6702 583.34 "Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1" 8.72 3887.2 - 759714 - - - 4.0106 - 2.231 0.617 - 491.2 1 2 0 0.0047 10 0 0 0 2.56E+06 2.71E+06 - - - 5.8366 1 230117_WJC_METTL3_WT_vs_EV_F06.21312.21312.2 1.36E-05 24-Oct K.NPLPVTLTNVVFR.L "sp|P22735|TGM1_HUMAN,tr|H0YMQ8|H0YMQ8_HUMAN" 2 1468.8402 999 53409 21312 2 1468.843541 735.4274 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 9.75 3887.7 - 350832 - - - 2.2753 - 2.339 0.529 - 254.8 1 2 0 0.0033 13 0 0 0 1.77E+06 0.00E+00 - - - 5.128 0.9662 230117_WJC_METTL3_WT_vs_EV_F06.21317.21317.2 0.123 20-Jun K.EGIPLIILAGK.K sp|P48200|IREB2_HUMAN 1 1122.7012 -1 53414 21317 2 1122.706576 562.3579 Iron-responsive element-binding protein 2 OS=Homo sapiens OX=9606 GN=IREB2 PE=1 SV=4 6.1 3888.4 - 190448 - - - 4.7475 - 1.283 0.183 - 48 3 2 0 0.0053 11 0 0 0 0.00E+00 0.00E+00 - - - 0.852 1 230117_WJC_METTL3_WT_vs_EV_F06.21324.21324.2 9.22E-05 22-Oct R.LFQVEYAIEAIK.L sp|P28066|PSA5_HUMAN 1 1422.7759 2.23 53420 21324 2 1422.778737 712.3952 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 4.53 3889.3 - 2.41E+06 - - - 2.0165 - 2.069 0.529 - 306.7 1 2 0 0.0029 12 0 0 0 2.75E+07 1.23E+07 - - - 4.8603 1 230117_WJC_METTL3_WT_vs_EV_F06.21325.21325.3 2.14E-06 Dec-68 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.83 53421 21325 3 1926.007518 643.0084 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3889.3 - 2.36E+06 - - - 2.1802 - 2.244 0.59 - 130.9 1 2 0 0.0042 18 0 0 0 1.69E+07 2.04E+07 - - - 7.1294 0.9998 230117_WJC_METTL3_WT_vs_EV_F06.21327.21327.3 6.29E-05 13/52 K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.92 53423 21327 3 1651.934464 551.6512 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3889.4 - 1.45E+06 - - - 1.7053 - 2.189 0.387 - 111.1 1 2 0 0.0028 14 0 0 0 1.15E+07 1.26E+07 - - - 4.9359 0.997 230117_WJC_METTL3_WT_vs_EV_F06.21331.21331.2 0.148 14-Aug K.QFLIDWVR.K "sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 2 1075.5815 0.61 53427 21331 2 1075.585156 538.798 ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2 5.84 3889.9 - 393316 - - - 3.4316 - 1.67 0.214 - 246.3 1 2 0 0.0037 8 0 0 0 1.90E+06 3.11E+06 - - - 2.1671 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.21335.21335.2 0.587 20-Sep R.NLIIEAVTNLR[166.11].L "sp|Q12789|TF3C1_HUMAN,tr|H3BU37|H3BU37_HUMAN" 2 1264.7379 0.92 53431 21335 2 1264.741236 633.3762 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 6 3890.3 - 265710 - - - 2.6725 - 1.835 0.181 - 295.8 1 2 0 0.0034 11 0 0 0 2.89E+06 3.12E+06 - - - 2.019 1 230117_WJC_METTL3_WT_vs_EV_F06.21343.21343.2 0.000939 13/18 K.C[160.03]MQLTDFILK[136.11].F "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1275.6447 0.71 53437 21343 2 1275.650063 638.8296 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.83 3891.4 - 1.38E+06 - - - 4.2308 - 2.303 0.466 - 547.2 1 2 0 0.0054 10 0 0 0 2.12E+07 2.97E+07 - - - 4.8097 1 230117_WJC_METTL3_WT_vs_EV_F06.21344.21344.2 9.11E-05 20-Oct R.EALDVLGAVLK[136.11].A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1134.674 1.35 53438 21344 2 1134.677392 568.3443 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3891.6 - 1.34E+06 - - - 3.0114 - 2.215 0.51 - 285.8 1 2 0 0.0034 11 0 0 0 9.16E+07 6.79E+07 - - - 4.9581 1 230117_WJC_METTL3_WT_vs_EV_F06.21346.21346.2 9.06E-06 13/18 K.C[160.03]MQLTDFILK.F "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1267.6305 0.71 53440 21346 2 1267.63612 634.8225 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.83 3891.8 - 887358 - - - 4.4603 - 2.344 0.502 - 520.5 1 2 0 0.0057 10 0 0 0 2.12E+07 2.97E+07 - - - 5.1248 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21349.21349.2 1.51E-05 20-Oct K.TLC[160.03]PLC[160.03]FSILK[136.11].G "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1358.7182 1.37 53443 21349 2 1358.718486 680.3664 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 7.74 3892.2 - 529766 - - - 0.2355 - 2.029 0.489 - 251.3 1 2 0 0.0003 11 0 0 0 4.45E+06 3.26E+06 - - - 4.5667 1 230117_WJC_METTL3_WT_vs_EV_F06.21350.21350.2 0.000354 24-Dec R.VLGATLLPDLIQK[136.11].V "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN,tr|H0YDG0|H0YDG0_HUMAN" 5 1387.853 1.67 53444 21350 2 1387.857562 694.9338 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.81 3892.3 - 398276 - - - 3.2857 - 2.398 0.508 - 406.7 1 2 0 0.0046 13 0 0 0 1.11E+07 6.66E+06 - - - 5.0364 1 230117_WJC_METTL3_WT_vs_EV_F06.21354.21354.2 0.032 13/28 R.TIAIIAEGIPEALTR.K sp|P53396|ACLY_HUMAN 1 1566.8981 1.53 53448 21354 2 1566.904145 784.4563 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.53 3892.9 - 235246 - - - 3.8528 - 2.739 0.508 - 578.5 1 2 0 0.006 15 0 0 0 1.34E+06 8.78E+05 - - - 5.2684 0.996 230117_WJC_METTL3_WT_vs_EV_F06.21355.21355.2 0.0981 14-Jul R.IPFAFWAR.Y "sp|Q96JG8|MAGD4_HUMAN,tr|A0A804HKI1|A0A804HKI1_HUMAN" 2 1006.5389 0.22 53449 21355 2 1006.538181 504.2767 Melanoma-associated antigen D4 OS=Homo sapiens OX=9606 GN=MAGED4 PE=1 SV=3 9.75 3893 - 190818 - - - -0.6865 - 1.284 0.272 - 149.7 1 2 0 -0.0007 8 0 0 0 1.03E+06 4.69E+06 - - - 1.8037 1 230117_WJC_METTL3_WT_vs_EV_F06.21359.21359.2 7.58E-08 13/26 R.VIVSDVQESFIWVR[166.11].Y sp|Q15393|SF3B3_HUMAN 1 1685.9016 1.16 53453 21359 2 1685.906479 843.9581 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3893.5 - 159051 - - - 2.878 - 2.832 0.643 - 465.6 1 2 0 0.0049 14 0 0 0 8.56E+06 7.41E+06 - - - 6.401 0.9854 230117_WJC_METTL3_WT_vs_EV_F06.21364.21364.2 0.172 22-Jul R.ALGATFGPLLLR.A "sp|O00459|P85B_HUMAN,tr|E9PFP1|E9PFP1_HUMAN" 2 1227.7339 -1 53457 21364 2 1227.738429 614.8742 Phosphatidylinositol 3-kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PIK3R2 PE=1 SV=2 9.79 3894.3 - 72099.9 - - - 3.6539 - 1.284 0.167 - 85.4 1 2 0 0.0045 12 0 0 0 0.00E+00 0.00E+00 - - - 0.9308 1 230117_WJC_METTL3_WT_vs_EV_F06.21369.21369.2 1.96E-06 24-Oct K.YVFLDPLAGAVTK[136.11].T "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|A8MWX3|WASH4_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 6 1400.7795 2.29 53462 21369 2 1400.784441 701.397 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 5.83 3894.9 - 273306 - - - 3.5252 - 2.146 0.504 - 239.1 1 2 0 0.0049 13 0 0 0 1.79E+07 7.85E+06 - - - 4.7218 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.21373.21373.2 0.000747 14-Aug K.NFAFLEFR[166.11].S "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1052.5319 1.49 53466 21373 2 1052.536878 527.2732 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3895.4 - 160875 - - - 4.7428 - 1.697 0.394 - 205.8 1 2 0 0.005 8 0 0 0 1.91E+07 1.29E+07 - - - 3.5445 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21376.21376.3 0.000296 14/40 K.LPLGLLLHPFK.D sp|O95486|SC24A_HUMAN 1 1246.7802 0.76 53469 21376 3 1246.784401 416.6007 Protein transport protein Sec24A OS=Homo sapiens OX=9606 GN=SEC24A PE=1 SV=2 8.76 3895.8 - 122239 - - - 3.3976 - 2.71 0.451 - 298.7 1 2 0 0.0042 11 0 0 0 1.68E+06 2.22E+06 - - - 6.3992 1 230117_WJC_METTL3_WT_vs_EV_F06.21382.21382.2 2.43E-05 22-Oct R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 53473 21382 2 1603.768072 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3896.6 - 4.18E+07 - - - 2.5764 - 1.933 0.52 - 321.1 1 2 0 0.0041 12 0 0 0 1.89E+08 0.00E+00 - - - 4.6146 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.21383.21383.2 2.08E-05 18-Dec K.LLEPVLLLGK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1093.7111 1.67 53474 21383 2 1093.716141 547.8628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3896.6 - 2.19E+07 - - - 4.6246 - 2.409 0.315 - 452.1 1 2 0 0.0051 10 0 0 0 8.33E+08 4.98E+08 - - - 3.8201 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.21384.21384.2 0.000511 13/18 K.LLEPVLLLGK[136.11].E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1101.7253 1.67 53475 21384 2 1101.728512 551.8699 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3896.7 - 1.59E+07 - - - 2.9309 - 2.442 0.323 - 537.9 1 2 0 0.0032 10 0 0 0 8.33E+08 4.98E+08 - - - 3.9178 1 230117_WJC_METTL3_WT_vs_EV_F06.21389.21389.2 6.16E-05 16-Oct R.DIDAFWLQR.Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1162.5771 1.46 53480 21389 2 1162.579839 582.2958 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3897.2 - 1.34E+06 - - - 2.3491 - 1.967 0.528 - 373.5 1 2 0 0.0027 9 0 0 0 2.58E+07 1.77E+07 - - - 4.8971 0.9983 230117_WJC_METTL3_WT_vs_EV_F06.21390.21390.2 0.0145 14-Aug K.SFDLLILK[136.11].E "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 955.5834 0.85 53481 21390 2 955.58616 478.799 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 5.55 3897.4 - 849398 - - - 2.9207 - 1.534 0.279 - 191.9 1 2 0 0.0028 8 0 0 0 4.00E+06 4.72E+06 - - - 2.3913 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.21391.21391.2 0.0635 14-Jul K.YLFDLPLK.V sp|Q5VUJ6|LRCH2_HUMAN 1 1007.5692 2.26 53482 21391 2 1007.573797 504.7919 Leucine-rich repeat and calponin homology domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LRCH2 PE=1 SV=2 5.83 3897.5 - 815765 - - - 4.5932 - 1.526 0.352 - 138 1 2 0 0.0046 8 0 0 0 2.77E+06 1.23E+06 - - - 2.9141 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21394.21394.2 0.000149 18-Sep K.LLLNLVDC[160.03]IR.S "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1227.7009 -1 53485 21394 2 1227.701066 614.8577 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 5.83 3897.9 - 519592 - - - 0.1116 - 2.061 0.472 - 271.5 1 2 0 0.0001 10 0 0 0 0.00E+00 0.00E+00 - - - 4.5458 0.9973 230117_WJC_METTL3_WT_vs_EV_F06.21395.21395.2 0.00374 22-Aug R.IAAQDYIIGVFR[166.11].K "sp|Q96RR1|PEO1_HUMAN,tr|A0A2R8Y4V4|A0A2R8Y4V4_HUMAN,tr|A0A2R8Y746|A0A2R8Y746_HUMAN" 3 1374.7535 1.24 53486 21395 2 1374.759839 688.384 Twinkle mtDNA helicase OS=Homo sapiens OX=9606 GN=TWNK PE=1 SV=1 5.84 3898 - 473521 - - - 4.6066 - 1.654 0.383 - 210.2 1 2 0 0.0063 12 0 0 0 4.04E+06 3.25E+06 - - - 3.1918 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.21396.21396.2 0.00904 18-Jul R.LIFQVLDAVK.Y "sp|Q14012|KCC1A_HUMAN,tr|C9JES6|C9JES6_HUMAN" 2 1144.6856 3.29 53487 21396 2 1144.687881 573.3501 Calcium\calmodulin-dependent protein kinase type 1 OS=Homo sapiens OX=9606 GN=CAMK1 PE=1 SV=1 5.84 3898.1 - 464055 - - - 1.9962 - 1.288 0.337 - 87.7 1 2 0 0.0023 10 0 0 0 1.47E+06 4.48E+05 - - - 2.2358 0.9957 230117_WJC_METTL3_WT_vs_EV_F06.21403.21403.2 0.0452 28-Jun R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 -1 53493 21403 2 1700.899213 851.4565 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3899.2 - 68089.2 - - - 0.418 - 1.16 0.249 - 61 1 2 0 0.0007 15 0 0 0 0.00E+00 0.00E+00 - - - 1.2448 0.999 230117_WJC_METTL3_WT_vs_EV_F06.21405.21405.2 0.0275 20-Oct K.IALLNVELELK.A sp|Q99832|TCPH_HUMAN 1 1253.7595 11.77 53494 21405 2 1253.762596 627.887 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.53 3899.4 - 1.02E+06 - - - 2.4781 - 1.93 0.261 - 279.4 1 2 0 0.0031 11 0 0 0 1.27E+07 1.08E+06 - - - 2.7465 1 230117_WJC_METTL3_WT_vs_EV_F06.21406.21406.2 0.000144 13/24 R.LDPETLESLGLIK[136.11].Q "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 1434.8061 2.89 53495 21406 2 1434.810409 718.4103 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 4.14 3899.5 - 213975 - - - 2.9948 - 2.38 0.506 - 576.8 1 2 0 0.0043 13 0 0 0 2.54E+07 8.79E+06 - - - 5.0024 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21407.21407.2 0.000434 16-Oct R.DIDAFWLQR[166.11].Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1172.5854 1.6 53496 21407 2 1172.586973 587.3 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3899.6 - 1.27E+06 - - - 1.3602 - 2.005 0.401 - 374.1 1 2 0 0.0016 9 0 0 0 2.54E+07 1.59E+07 - - - 4.0148 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21410.21410.2 2.78E-06 22-Sep R.LGAPGFAWEPFR.G "sp|Q9HCM7|FBSL_HUMAN,tr|A0A3B3IRR3|A0A3B3IRR3_HUMAN,tr|A0A7P0Z485|A0A7P0Z485_HUMAN" 3 1346.6772 1.84 53499 21410 2 1346.679863 674.3459 Fibrosin-1-like protein OS=Homo sapiens OX=9606 GN=FBRSL1 PE=1 SV=4 6 3899.9 - 249532 - - - 2.0094 - 2.17 0.437 - 311.9 1 2 0 0.0027 12 0 0 0 2.77E+06 1.50E+06 - - - 4.3063 1 230117_WJC_METTL3_WT_vs_EV_F06.21414.21414.2 1.08E-05 22-Oct R.EVAAGYLVPLLR.S sp|Q13395|TARB1_HUMAN 1 1299.7551 2.13 53503 21414 2 1299.756557 650.8848 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6.1 3900.4 - 86170.2 - - - 1.1418 - 2.265 0.506 - 454 1 2 0 0.0015 12 0 0 0 3.07E+06 1.44E+06 - - - 4.929 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.21417.21417.2 0.000752 22-Oct R.EVAAGYLVPLLR[166.11].S sp|Q13395|TARB1_HUMAN 1 1309.7633 2.13 53506 21417 2 1309.76946 655.8889 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6.1 3900.7 - 67553.5 - - - 4.6703 - 2.19 0.431 - 409.6 1 2 0 0.0061 12 0 0 0 3.07E+06 1.44E+06 - - - 4.285 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.21422.21422.2 0.000553 14-Sep K.NFAFLEFR.S "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1042.5236 1.49 53509 21422 2 1042.527383 522.2691 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3901.3 - 3.02E+06 - - - 3.6133 - 1.732 0.442 - 372.4 1 2 0 0.0038 8 0 0 0 1.91E+07 1.29E+07 - - - 3.961 0.9154 230117_WJC_METTL3_WT_vs_EV_F06.21425.21425.2 0.602 14-Jul N.GVSQLIQR.E sp|P48201|AT5G3_HUMAN 1 899.5189 0.92 53512 21425 2 899.520606 450.7667 "ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1" 9.75 3901.7 - 1.21E+06 - - - 1.9355 - 1.703 0.226 - 215.1 1 1 0 0.0017 8 0 0 0 1.55E+08 1.69E+08 - - - 2.3154 1 230117_WJC_METTL3_WT_vs_EV_F06.21426.21426.2 5.98E-05 18-Nov K.QEVPIIIVFR.A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1212.723 1.35 53513 21426 2 1212.725864 607.3688 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3901.8 - 755681 - - - 2.3253 - 2.231 0.538 - 447.2 1 2 0 0.0028 10 0 0 0 2.52E+07 1.86E+07 - - - 5.2537 1 230117_WJC_METTL3_WT_vs_EV_F06.21427.21427.2 0.000312 18-Nov K.LFEISDIVIK.D sp|Q9NSD9|SYFB_HUMAN 1 1175.6802 3.43 53514 21427 2 1175.681274 588.8474 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 4.37 3901.9 - 740542 - - - 0.9339 - 2.144 0.473 - 354.6 1 2 0 0.0011 10 0 0 0 9.53E+06 2.78E+06 - - - 4.6631 1 230117_WJC_METTL3_WT_vs_EV_F06.21428.21428.2 0.000655 18-Nov K.QEVPIIIVFR[166.11].A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1222.7313 1.35 53515 21428 2 1222.734528 612.3729 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3902 - 646163 - - - 2.6285 - 2.162 0.517 - 447.6 1 2 0 0.0032 10 0 0 0 2.52E+07 1.86E+07 - - - 5.0107 0.999 230117_WJC_METTL3_WT_vs_EV_F06.21430.21430.2 0.0203 14-Aug K.SFDLLILK.E "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 947.5692 0.85 53517 21430 2 947.571455 474.7919 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 5.55 3902.3 - 585988 - - - 2.4125 - 1.285 0.389 - 195.9 1 2 0 0.0023 8 0 0 0 4.00E+06 4.72E+06 - - - 2.6697 1 230117_WJC_METTL3_WT_vs_EV_F06.21431.21431.2 6.65E-05 15/24 R.LLGNTFVALSDLR.C "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1417.7929 3.23 53518 21431 2 1419.790687 709.9037 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.84 3902.4 - 373547 - - - 1409.0718 - 2.709 0.509 - 746.4 1 2 0 1.9978 13 0 0 0 8.72E+07 2.70E+07 - - - 4.7309 1 230117_WJC_METTL3_WT_vs_EV_F06.21433.21433.2 1.65E-08 16/24 K.TVQTAVFLYSLYK.E "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 1531.8286 1.02 53520 21433 2 1531.832022 766.9216 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.17 3902.7 - 333034 - - - 2.213 - 2.929 0.616 - 649.8 1 2 0 0.0034 13 0 0 0 7.26E+06 7.12E+06 - - - 6.3479 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21434.21434.2 0.00117 18-Dec K.LFEISDIVIK[136.11].D sp|Q9NSD9|SYFB_HUMAN 1 1183.6944 3.51 53521 21434 2 1183.696987 592.8545 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 4.37 3902.8 - 331255 - - - 2.2058 - 2.102 0.392 - 349.5 1 2 0 0.0026 10 0 0 0 9.76E+06 2.78E+06 - - - 4.0091 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21438.21438.2 6.56E-06 30-Dec K.TFVNITPAEVGVLVGK.D "sp|P07737|PROF1_HUMAN,tr|I3L3D5|I3L3D5_HUMAN" 2 1642.9294 0.54 53525 21438 2 1642.933282 822.472 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 5.66 3903.3 - 222088 - - - 2.358 - 2.044 0.479 - 318 1 2 0 0.0039 16 0 0 0 2.66E+06 4.95E+06 - - - 4.3353 1 230117_WJC_METTL3_WT_vs_EV_F06.21441.21441.2 6.99E-06 26-Dec R.VIVSDVQESFIWVR.Y sp|Q15393|SF3B3_HUMAN 1 1675.8934 1.16 53528 21441 2 1675.900548 838.954 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3903.7 - 195379 - - - 4.2908 - 2.446 0.568 - 387.9 1 2 0 0.0072 14 0 0 0 8.56E+06 7.41E+06 - - - 5.4786 1 230117_WJC_METTL3_WT_vs_EV_F06.21443.21443.2 1.71E-13 18/32 R.VLALSVETDYTFPLAEK[136.11].V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN" 5 1903.007 0.89 53529 21443 2 1903.010441 952.5108 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 4.14 3904.1 - 41595.8 - - - 1.8103 - 4.244 0.695 - 855.8 1 2 0 0.0034 17 0 0 0 3.10E+06 3.47E+06 - - - 7.727 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.21449.21449.2 0.002 15/24 K.LLLDTFEYQGLVK[136.11].H "sp|Q7Z7K6|CENPV_HUMAN,tr|A0A0M3HER2|A0A0M3HER2_HUMAN" 2 1545.8534 1.67 53533 21449 2 1545.853277 773.934 Centromere protein V OS=Homo sapiens OX=9606 GN=CENPV PE=1 SV=1 4.37 3904.6 - 946832 - - - -0.077 - 2.175 0.413 - 461.8 1 2 0 -0.0001 13 0 0 0 8.10E+06 4.85E+06 - - - 4.0856 1 230117_WJC_METTL3_WT_vs_EV_F06.21450.21450.2 5.24E-07 16/24 K.VSASPLLYTLIEK[136.11].T "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1440.8319 2.72 53534 21450 2 1440.837063 721.4232 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 5.97 3904.7 - 817955 - - - 3.5604 - 3.099 0.562 - 1046.4 1 2 0 0.0051 13 0 0 0 2.50E+07 9.19E+06 - - - 6.0933 1 230117_WJC_METTL3_WT_vs_EV_F06.21456.21456.2 4.25E-10 13/32 R.EIISEMGELGVLGPTIK.G "sp|Q92947|GCDH_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKT3|K7EKT3_HUMAN" 3 1784.9594 1.96 53540 21456 2 1784.953838 893.487 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.25 3905.5 - 402060 - - - -3.1093 - 2.88 0.594 - 484.6 1 2 0 -0.0056 17 0 0 0 1.24E+06 6.33E+05 - - - 6.0272 1 230117_WJC_METTL3_WT_vs_EV_F06.21458.21458.2 2.13E-08 Dec-32 R.EIISEMGELGVLGPTIK[136.11].G "sp|Q92947|GCDH_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKT3|K7EKT3_HUMAN" 3 1792.9736 -1 53542 21458 2 1792.975006 897.4941 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.25 3905.7 - 309972 - - - 0.7909 - 2.662 0.59 - 384.2 1 2 0 0.0014 17 0 0 0 0.00E+00 0.00E+00 - - - 5.8054 1 230117_WJC_METTL3_WT_vs_EV_F06.21462.21462.2 4.02E-05 24-Nov K.VFSATLGLVDIVK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1360.7966 1.2 53544 21462 2 1360.797389 681.4056 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3906.2 - 4.68E+06 - - - 0.5776 - 2.253 0.586 - 317.6 1 2 0 0.0008 13 0 0 0 1.70E+08 1.42E+08 - - - 5.4536 1 230117_WJC_METTL3_WT_vs_EV_F06.21463.21463.2 1.80E-07 13/24 K.VFSATLGLVDIVK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1368.8108 1.2 53545 21463 2 1368.811834 685.4127 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3906.3 - 3.81E+06 - - - 0.7532 - 2.687 0.576 - 485.9 1 2 0 0.001 13 0 0 0 1.70E+08 1.42E+08 - - - 5.8318 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.21464.21464.2 0.00419 16-Jul R.FWYFVSQLK[136.11].K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1224.6423 0.76 53546 21464 2 1224.644021 613.3284 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3906.3 - 3.48E+06 - - - 1.4208 - 1.313 0.445 - 163 1 2 0 0.0017 9 0 0 0 6.66E+07 8.75E+07 - - - 3.115 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.21466.21466.2 3.50E-05 16-Sep R.FWYFVSQLK.K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1216.6281 0.76 53548 21466 2 1216.632128 609.3213 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3906.4 - 1.87E+06 - - - 3.3264 - 1.847 0.507 - 304.8 1 2 0 0.004 9 0 0 0 6.66E+07 8.75E+07 - - - 4.5595 0.9998 230117_WJC_METTL3_WT_vs_EV_F06.21467.21467.3 0.000433 Oct-48 R.LLGNTFVALSDLR.C "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1417.7929 2.48 53549 21467 3 1417.794211 473.6049 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.84 3906.5 - 1.21E+06 - - - 0.9141 - 1.819 0.405 - 143.2 1 2 0 0.0013 13 0 0 0 4.92E+06 1.98E+06 - - - 4.6771 1 230117_WJC_METTL3_WT_vs_EV_F06.21468.21468.2 1.47E-05 22-Nov K.VVYTSLQWASLQ.- "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN" 2 1393.7242 - 53550 21468 2 1393.722657 697.8694 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 5.49 3906.6 - 1.18E+06 - - - -1.0827 - 2.389 0.481 - 281.1 1 2 0 -0.0015 12 0 0 0 - - - - - 4.8846 1 230117_WJC_METTL3_WT_vs_EV_F06.21469.21469.2 9.71E-06 13/24 K.LEVAPISDIIAIK.S "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 6 1380.8228 2.85 53551 21469 2 1380.823682 691.4187 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 4.37 3906.6 - 1.17E+06 - - - 0.6257 - 2.395 0.478 - 420.4 1 2 0 0.0009 13 0 0 0 9.77E+07 3.43E+07 - - - 4.8128 1 230117_WJC_METTL3_WT_vs_EV_F06.21472.21472.2 1.36E-10 16/26 K.FGGDFLVYPGDPLR.F "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN" 4 1551.7722 8.77 53554 21472 2 1551.775612 776.8934 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.21 3907 - 684447 - - - 2.2123 - 3.242 0.62 - 776.3 1 2 0 0.0034 14 0 0 0 2.10E+07 2.40E+06 - - - 6.5708 1 230117_WJC_METTL3_WT_vs_EV_F06.21476.21476.2 0.000339 13/24 K.LDNLLLDTEGFVK[136.11].L sp|Q16513|PKN2_HUMAN 1 1483.8014 1.43 53558 21476 2 1483.802186 742.908 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.03 3907.4 - 555117 - - - 0.556 - 2.529 0.442 - 372.9 1 2 0 0.0008 13 0 0 0 5.46E+06 3.82E+06 - - - 4.6866 1 230117_WJC_METTL3_WT_vs_EV_F06.21478.21478.2 4.24E-05 13/22 K.IILDLISESPIK.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1339.7963 1.12 53560 21478 2 1339.797665 670.9054 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3907.6 - 377517 - - - 1.0419 - 2.775 0.524 - 536.3 1 2 0 0.0014 12 0 0 0 5.14E+08 4.60E+08 - - - 5.5963 1 230117_WJC_METTL3_WT_vs_EV_F06.21483.21483.2 0.000649 13/22 K.IILDLISESPIK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1347.8105 1.12 53564 21483 2 1347.812897 674.9125 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3908.1 - 962337 - - - 1.8014 - 2.67 0.482 - 532 1 2 0 0.0024 12 0 0 0 5.14E+08 4.60E+08 - - - 5.1843 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21484.21484.2 5.15E-07 28-Nov K.IVFVPGC[160.03]SIPLTIVK[136.11].S sp|P54136|SYRC_HUMAN 1 1649.967 1.57 53565 21484 2 1649.966898 825.9908 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3908.2 - 479393 - - - -0.0539 - 2.165 0.465 - 210.3 1 2 0 -0.0001 15 0 0 0 7.80E+07 4.97E+07 - - - 4.3745 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.21485.21485.2 0.0167 16-Aug R.LLPDFLLER[166.11].R "sp|Q12894|IFRD2_HUMAN,tr|H7C444|H7C444_HUMAN,tr|A0A0R4J2F6|A0A0R4J2F6_HUMAN" 3 1124.6469 0.41 53566 21485 2 1124.649255 563.3307 Interferon-related developmental regulator 2 OS=Homo sapiens OX=9606 GN=IFRD2 PE=1 SV=3 4.37 3908.3 - 283226 - - - 2.0798 - 2.038 0.281 - 152.2 1 2 0 0.0023 9 0 0 0 4.29E+06 1.06E+07 - - - 3.1755 1 230117_WJC_METTL3_WT_vs_EV_F06.21486.21486.2 6.76E-06 15/24 R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 1.56 53567 21486 2 1448.795124 725.4024 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3908.4 - 238466 - - - 3.3393 - 3.252 0.536 - 904.6 1 2 0 0.0048 13 0 0 0 2.35E+08 1.51E+08 - - - 6.025 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21487.21487.2 5.95E-07 14/24 K.LDNLLLDTEGFVK.L sp|Q16513|PKN2_HUMAN 1 1475.7872 1.45 53568 21487 2 1475.788473 738.9009 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.03 3908.5 - 192250 - - - 0.889 - 2.669 0.391 - 559.6 1 2 0 0.0013 13 0 0 0 5.53E+06 3.82E+06 - - - 4.4481 1 230117_WJC_METTL3_WT_vs_EV_F06.21488.21488.2 6.39E-06 16/26 K.VLLLSSPGLEELYR[166.11].C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1597.8955 0.96 53569 21488 2 1597.896843 799.955 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3908.6 - 154755 - - - 0.8536 - 2.912 0.447 - 802.2 1 2 0 0.0014 14 0 0 0 3.86E+07 4.01E+07 - - - 5.0243 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.21490.21490.2 0.0147 16-Aug R.LDLLPFYAR[166.11].L sp|Q9HAU5|RENT2_HUMAN 1 1116.6207 1.37 53571 21490 2 1116.623658 559.3176 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 5.84 3908.9 - 92287.8 - - - 2.6482 - 1.749 0.231 - 143.4 1 2 0 0.003 9 0 0 0 3.88E+06 2.84E+06 - - - 2.3636 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.21494.21494.2 0.037 26-Sep K.VLLLSSPGLEELYR.C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1587.8872 0.96 53572 21494 2 1587.886166 794.9509 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3909.3 - 7.15E+06 - - - -0.6568 - 1.861 0.314 - 229.4 1 2 0 -0.001 14 0 0 0 3.86E+07 4.01E+07 - - - 2.9185 1 230117_WJC_METTL3_WT_vs_EV_F06.21506.21506.2 0.000124 20-Nov K.LPDVYGVFQFK.V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1311.6863 1.34 53580 21506 2 1311.687803 656.8504 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.83 3910.3 - 2.36E+06 - - - 1.1276 - 2.322 0.516 - 420.2 1 2 0 0.0015 11 0 0 0 2.63E+07 1.96E+07 - - - 5.1307 1 230117_WJC_METTL3_WT_vs_EV_F06.21507.21507.2 0.00148 16-Dec R.IDLAVLLGK.T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 940.5957 1.85 53581 21507 2 940.596532 471.3051 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3910.4 - 2.45E+06 - - - 0.8654 - 2.374 0.497 - 373.6 1 2 0 0.0008 9 0 0 0 1.83E+08 9.89E+07 - - - 5.2129 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.21508.21508.2 0.00028 22-Nov R.YFPTQALNFAFK[136.11].D "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 1453.7485 1.17 53582 21508 2 1453.747777 727.8815 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.59 3910.6 - 2.10E+06 - - - -0.5228 - 2.058 0.39 - 395.7 1 2 0 -0.0008 12 0 0 0 1.75E+08 1.49E+08 - - - 3.8203 1 230117_WJC_METTL3_WT_vs_EV_F06.21509.21509.2 0.00576 16-Nov R.IDLAVLLGK[136.11].T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 948.6099 1.85 53583 21509 2 948.610193 475.3122 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3910.7 - 1.48E+06 - - - 0.2899 - 2.325 0.483 - 299.4 1 2 0 0.0003 9 0 0 0 1.83E+08 9.89E+07 - - - 5.0493 1 230117_WJC_METTL3_WT_vs_EV_F06.21510.21510.3 3.49E-07 14/48 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.7 53584 21510 3 1438.784558 480.6013 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3910.8 - 1.03E+06 - - - 1.7668 - 2.791 0.501 - 302.3 1 2 0 0.0025 13 0 0 0 7.45E+06 4.37E+06 - - - 6.9078 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21511.21511.2 0.0635 14-Sep K.LYDFYLFK.C sp|Q2TAL8|QRIC1_HUMAN 1 1107.5641 2.46 53585 21511 2 1107.565374 554.7893 Transcriptional regulator QRICH1 OS=Homo sapiens OX=9606 GN=QRICH1 PE=1 SV=1 5.83 3910.9 - 1.03E+06 - - - 1.1647 - 1.845 0.362 - 210.6 1 2 0 0.0013 8 0 0 0 8.06E+06 3.28E+06 - - - 3.5615 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.21512.21512.2 0.295 14-Aug R.SVFLTFLR.M "sp|Q9H1I8|ASCC2_HUMAN,tr|B1AH59|B1AH59_HUMAN" 2 981.5648 1.67 53586 21512 2 981.565553 491.7897 Activating signal cointegrator 1 complex subunit 2 OS=Homo sapiens OX=9606 GN=ASCC2 PE=1 SV=3 9.47 3911.1 - 1.02E+06 - - - 0.815 - 1.849 0.259 - 254.4 1 2 0 0.0008 8 0 0 0 5.17E+06 3.10E+06 - - - 2.8075 0.999 230117_WJC_METTL3_WT_vs_EV_F06.21513.21513.2 3.85E-05 24-Oct R.FDNVLPVSLAFDK.C "sp|O95352|ATG7_HUMAN,tr|H7BZ92|H7BZ92_HUMAN,tr|H7C2R3|H7C2R3_HUMAN,tr|H7C2J8|H7C2J8_HUMAN" 4 1463.766 3.84 53587 21513 2 1463.764622 732.8903 Ubiquitin-like modifier-activating enzyme ATG7 OS=Homo sapiens OX=9606 GN=ATG7 PE=1 SV=1 4.21 3911.2 - 810118 - - - -0.9626 - 1.866 0.416 - 230.3 1 2 0 -0.0014 13 0 0 0 4.72E+06 1.23E+06 - - - 3.7141 0.9998 230117_WJC_METTL3_WT_vs_EV_F06.21515.21515.3 0.000206 14/48 R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 2.06 53589 21515 3 1448.791974 483.9374 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3911.5 - 737906 - - - 1.1651 - 2.475 0.35 - 338.6 1 2 0 0.0017 13 0 0 0 9.76E+06 4.73E+06 - - - 4.8988 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.21516.21516.2 0.306 14/24 K.QLLDSGLPSLLVR.S "sp|Q9NR09|BIRC6_HUMAN,tr|A0A3B3IUB9|A0A3B3IUB9_HUMAN" 2 1409.8242 2.64 53590 21516 2 1409.822888 705.9194 Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=BIRC6 PE=1 SV=2 5.84 3911.6 - 715818 - - - -0.9413 - 2.243 0.33 - 663.6 1 2 0 -0.0013 13 0 0 0 6.59E+06 2.49E+06 - - - 3.5512 0.999 230117_WJC_METTL3_WT_vs_EV_F06.21517.21517.2 0.0162 14-Jul K.ENLLDFIK[136.11].H "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 998.5528 2.08 53591 21517 2 998.552597 500.2837 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.37 3911.7 - 683903 - - - -0.2003 - 1.746 0.3 - 169.9 1 2 0 -0.0002 8 0 0 0 6.82E+07 3.28E+07 - - - 2.9376 0.9052 230117_WJC_METTL3_WT_vs_EV_F06.21520.21520.2 5.98E-05 26-Oct K.VLLVGADNFTLLGK.P "sp|Q7Z2W9|RM21_HUMAN,tr|H3BUY0|H3BUY0_HUMAN,tr|F5H7V8|F5H7V8_HUMAN" 3 1458.8446 0.78 53594 21520 2 1458.841828 730.4296 "39S ribosomal protein L21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL21 PE=1 SV=2" 5.81 3912.1 - 573514 - - - -1.9111 - 1.983 0.49 - 187.8 1 1 0 -0.0028 14 0 0 0 3.09E+06 3.98E+06 - - - 4.3773 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.21528.21528.2 0.00892 14-Aug K.ENLLDFIK.H "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 990.5386 2.08 53601 21528 2 990.537826 496.2766 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.37 3912.9 - 2.98E+07 - - - -0.7784 - 1.81 0.29 - 266.4 1 2 0 -0.0008 8 0 0 0 6.82E+07 3.28E+07 - - - 2.9721 0.9785 230117_WJC_METTL3_WT_vs_EV_F06.21536.21536.2 1.04 16-Jul K.AIVLAAIFR.C "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 972.612 1.58 53609 21536 2 972.615398 487.3133 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 9.79 3913.4 - 1.68E+06 - - - 3.4556 - 1.485 0.05 - 96.8 1 2 0 0.0034 9 0 0 0 3.30E+06 2.09E+06 - - - 0.5532 0.9988 230117_WJC_METTL3_WT_vs_EV_F06.21538.21538.2 0.00386 16-Aug K.DLPPILLVR.G sp|P55011|S12A2_HUMAN 1 1034.6488 999 53611 21538 2 1034.649058 518.3317 Solute carrier family 12 member 2 OS=Homo sapiens OX=9606 GN=SLC12A2 PE=1 SV=1 5.84 3913.6 - 1.22E+06 - - - 0.2329 - 1.32 0.354 - 247.9 1 2 0 0.0002 9 0 0 0 3.37E+06 0.00E+00 - - - 2.4588 0.9959 230117_WJC_METTL3_WT_vs_EV_F06.21539.21539.2 0.0246 24-Sep K.QLLDSGLPSLLVR[166.11].S "sp|Q9NR09|BIRC6_HUMAN,tr|A0A3B3IUB9|A0A3B3IUB9_HUMAN" 2 1419.8325 2.64 53612 21539 2 1419.829715 710.9235 Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=BIRC6 PE=1 SV=2 5.84 3913.7 - 935808 - - - -1.9509 - 1.802 0.278 - 257.5 1 2 0 -0.0028 13 0 0 0 6.59E+06 2.49E+06 - - - 2.6049 1 230117_WJC_METTL3_WT_vs_EV_F06.21547.21547.2 2.51E-06 22-Nov R.YFPTQALNFAFK.D "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 1445.7343 1.17 53618 21547 2 1445.732052 723.8744 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.59 3914.7 - 8.31E+06 - - - -1.5805 - 2.135 0.58 - 415.7 1 2 0 -0.0023 12 0 0 0 1.75E+08 1.49E+08 - - - 5.3198 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.21548.21548.2 0.00143 14-Sep R.ILEFFGLK.K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 965.5586 2.53 53619 21548 2 965.557121 483.7866 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3914.8 - 4.88E+06 - - - -1.5369 - 1.643 0.399 - 205.8 1 2 0 -0.0015 8 0 0 0 8.45E+07 3.35E+07 - - - 3.485 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.21549.21549.2 0.0227 14-Oct R.ILEFFGLK[136.11].K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 973.5728 2.53 53620 21549 2 973.573605 487.7937 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3915 - 2.47E+06 - - - 0.8217 - 1.803 0.305 - 243.1 1 2 0 0.0008 8 0 0 0 8.45E+07 3.35E+07 - - - 3.0712 1 230117_WJC_METTL3_WT_vs_EV_F06.21568.21568.2 2.68E-05 14/24 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.56 53638 21568 2 1438.782001 720.3983 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3917.3 - 2.69E+06 - - - -0.0104 - 2.973 0.518 - 925.4 1 2 0 0 13 0 0 0 2.35E+08 1.51E+08 - - - 5.6634 0.9597 230117_WJC_METTL3_WT_vs_EV_F06.21571.21571.2 0.000576 24-Jul K.VALVTASTDGIGF.A "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN" 5 1249.6554 - 53641 21571 2 1249.656098 625.835 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 3.8 3917.5 - 1.11E+07 - - - 0.5442 - 1.551 0.431 - 147.4 1 1 0 0.0007 13 0 0 0 - - - - - 3.3506 1 230117_WJC_METTL3_WT_vs_EV_F06.21572.21572.2 1.82E-05 13/26 R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.12 53642 21572 2 1478.89532 740.4549 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3917.6 - 1.09E+07 - - - 0.0805 - 2.554 0.599 - 419.9 1 2 0 0.0001 14 0 0 0 4.19E+08 3.75E+08 - - - 5.8182 1 230117_WJC_METTL3_WT_vs_EV_F06.21573.21573.2 1.30E-05 20-Nov K.AFVDFLSDEIK.E sp|Q07021|C1QBP_HUMAN 1 1282.6445 1.69 53643 21573 2 1282.644692 642.3295 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.03 3917.6 - 7.14E+06 - - - 0.1349 - 2.097 0.541 - 371.8 1 2 0 0.0002 11 0 0 0 1.67E+07 9.88E+06 - - - 5.04 1 230117_WJC_METTL3_WT_vs_EV_F06.21574.21574.2 0.000328 18-Oct R.IQFFAIEIAR.N sp|Q9BVG4|PBDC1_HUMAN 1 1206.6761 4.39 53644 21574 2 1206.676285 604.3453 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 6 3917.7 - 5.70E+06 - - - 0.1583 - 2.187 0.495 - 349 1 2 0 0.0002 10 0 0 0 1.85E+07 4.22E+06 - - - 4.8813 1 230117_WJC_METTL3_WT_vs_EV_F06.21576.21576.2 2.26E-06 13/22 K.WLAPDGLIFPDR[166.11].A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1408.7379 0.8 53646 21576 2 1408.73724 705.3762 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3917.9 - 3.98E+06 - - - -0.4373 - 2.819 0.51 - 591.2 1 2 0 -0.0006 12 0 0 0 6.41E+07 7.97E+07 - - - 5.5346 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.21577.21577.2 0.00161 20-Nov K.AFVDFLSDEIK[136.11].E sp|Q07021|C1QBP_HUMAN 1 1290.6587 -1 53647 21577 2 1290.658259 646.3366 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.03 3917.9 - 3.58E+06 - - - -0.3564 - 1.798 0.364 - 388.5 1 2 0 -0.0005 11 0 0 0 0.00E+00 0.00E+00 - - - 3.3165 1 230117_WJC_METTL3_WT_vs_EV_F06.21578.21578.2 2.14E-08 19/26 K.TALALAIAQELGSK.V "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1384.7926 2.06 53648 21578 2 1384.791943 693.4036 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 5.66 3918 - 3.00E+06 - - - -0.46 - 3.714 0.611 - 1651.2 1 2 0 -0.0006 14 0 0 0 9.38E+06 4.56E+06 - - - 6.8463 0.9944 230117_WJC_METTL3_WT_vs_EV_F06.21581.21581.2 0.387 16-Jul K.EVNLVLLLK.N "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1039.6641 999 53651 21581 2 1039.668009 520.8393 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 6.1 3918.3 - 2.06E+06 - - - 3.7291 - 1.639 0.175 - 144.9 1 2 0 0.0039 9 0 0 0 4.99E+06 0.00E+00 - - - 1.7618 0.999 230117_WJC_METTL3_WT_vs_EV_F06.21582.21582.2 0.0525 13/24 R.LGPLLLDPSLAVR[166.11].E sp|Q7Z4Q2|HEAT3_HUMAN 1 1372.8318 -1 53652 21582 2 1372.831579 687.4232 HEAT repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=HEATR3 PE=1 SV=2 5.84 3918.5 - 2.00E+06 - - - -0.1297 - 2.388 0.227 - 425.3 1 2 0 -0.0002 13 0 0 0 0.00E+00 0.00E+00 - - - 2.9516 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.21586.21586.2 0.0637 18-Nov R.SLGPVELLLR[166.11].G "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1105.6735 2.47 53656 21586 2 1105.67305 553.844 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.72 3918.9 - 1.61E+06 - - - -0.3753 - 2.075 0.36 - 409.2 1 2 0 -0.0004 10 0 0 0 2.14E+07 8.64E+06 - - - 3.7374 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21587.21587.2 2.78E-05 26-Nov K.LFGIESSSGTILWK.Q sp|Q8N766|EMC1_HUMAN 1 1536.8188 -1 53657 21587 2 1536.821639 769.4167 ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1 6 3919 - 1.51E+06 - - - 1.8506 - 1.964 0.455 - 308 1 2 0 0.0028 14 0 0 0 0.00E+00 0.00E+00 - - - 4.0946 0.9933 230117_WJC_METTL3_WT_vs_EV_F06.21589.21589.2 0.11 26-Mar R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.12 53658 21589 2 1470.880937 736.4478 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3919.2 - 2.09E+08 - - - -0.0435 - 0.844 0.349 - 21.2 2 2 0 -0.0001 14 0 0 0 4.19E+08 3.75E+08 - - - 1.0586 1 230117_WJC_METTL3_WT_vs_EV_F06.21591.21591.2 3.86E-05 22-Dec K.WLAPDGLIFPDR.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1398.7296 0.8 53660 21591 2 1398.727276 700.3721 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3919.4 - 2.17E+07 - - - -1.6515 - 2.67 0.521 - 550.9 1 2 0 -0.0023 12 0 0 0 6.41E+07 7.97E+07 - - - 5.4724 1 230117_WJC_METTL3_WT_vs_EV_F06.21592.21592.3 8.27E-08 15/52 R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 -1 53661 21592 3 1478.89444 493.9723 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3919.4 - 1.86E+07 - - - -0.5146 - 2.762 0.599 - 334.6 1 2 0 -0.0008 14 0 0 0 0.00E+00 0.00E+00 - - - 7.918 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21593.21593.3 3.61E-05 Dec-52 R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 -1 53662 21593 3 1470.880276 491.3009 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3919.5 - 1.80E+07 - - - -0.4929 - 2.395 0.515 - 189.3 1 2 0 -0.0007 14 0 0 0 0.00E+00 0.00E+00 - - - 6.6026 1 230117_WJC_METTL3_WT_vs_EV_F06.21595.21595.2 7.91E-10 15/30 K.LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1793.9075 -1 53664 21595 2 1793.905665 897.961 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3919.6 - 6.18E+06 - - - -1.0229 - 2.957 0.615 - 527.5 1 2 0 -0.0018 16 0 0 0 0.00E+00 0.00E+00 - - - 6.2483 0.994 230117_WJC_METTL3_WT_vs_EV_F06.21596.21596.2 0.00484 14-Jul R.SWLLPVIR[166.11].D sp|Q5JTH9|RRP12_HUMAN 1 992.6047 -1 53665 21596 2 992.604997 497.3096 RRP12-like protein OS=Homo sapiens OX=9606 GN=RRP12 PE=1 SV=2 9.47 3919.7 - 5.91E+06 - - - 0.3425 - 1.419 0.123 - 276.1 1 2 0 0.0003 8 0 0 0 0.00E+00 0.00E+00 - - - 1.0048 1 230117_WJC_METTL3_WT_vs_EV_F06.21597.21597.2 3.03E-07 17/30 K.LFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1783.8992 -1 53666 21597 2 1783.898031 892.9569 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3919.8 - 4.96E+06 - - - -0.6721 - 3.217 0.61 - 883.4 1 2 0 -0.0012 16 0 0 0 0.00E+00 0.00E+00 - - - 6.4188 1 230117_WJC_METTL3_WT_vs_EV_F06.21598.21598.2 1.20E-05 15/28 R.ELALALQEALEPAVR.L sp|Q5RKV6|EXOS6_HUMAN 1 1621.9039 -1 53667 21598 2 1621.902773 811.9592 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 4.25 3919.9 - 4.61E+06 - - - -0.7084 - 3.15 0.482 - 867.8 1 2 0 -0.0011 15 0 0 0 0.00E+00 0.00E+00 - - - 5.4216 0.9942 230117_WJC_METTL3_WT_vs_EV_F06.21602.21602.2 0.611 16-Aug K.ISVLYSFLR[166.11].S "sp|Q13206|DDX10_HUMAN,tr|A0A3B3ISR7|A0A3B3ISR7_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 3 1106.6364 -1 53671 21602 2 1106.634825 554.3255 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 8.75 3920.2 - 3.90E+06 - - - -1.379 - 1.583 0.204 - 204.3 1 2 0 -0.0015 9 0 0 0 0.00E+00 0.00E+00 - - - 1.8761 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21603.21603.2 0.000151 15/26 R.LAQVSPELLLASVR[166.11].R sp|O43592|XPOT_HUMAN 1 1504.8852 -1 53672 21603 2 1504.885826 753.4499 Exportin-T OS=Homo sapiens OX=9606 GN=XPOT PE=1 SV=2 6 3920.3 - 3.85E+06 - - - 0.3834 - 2.23 0.429 - 658.3 1 2 0 0.0006 14 0 0 0 0.00E+00 0.00E+00 - - - 4.222 1 230117_WJC_METTL3_WT_vs_EV_F06.21604.21604.2 7.93E-05 13/20 Q.AFADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1170.7012 -1 53673 21604 2 1170.698316 586.3579 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3920.4 - 3.81E+06 - - - -2.5028 - 2.23 0.509 - 434.5 1 1 0 -0.0029 11 0 0 0 0.00E+00 0.00E+00 - - - 4.9692 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.21605.21605.2 8.46E-06 13/26 K.IPVDTYNNILTVLK.L sp|Q96QK1|VPS35_HUMAN 1 1601.9029 2.12 53674 21605 2 1601.902066 801.9587 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 5.83 3920.5 - 3.67E+06 - - - -0.495 - 2.277 0.464 - 276.6 1 2 0 -0.0008 14 0 0 0 8.21E+06 3.88E+06 - - - 4.5328 1 230117_WJC_METTL3_WT_vs_EV_F06.21615.21615.2 2.55E-06 13/26 R.LAQVSPELLLASVR.R sp|O43592|XPOT_HUMAN 1 1494.877 -1 53683 21615 2 1494.876998 748.4458 Exportin-T OS=Homo sapiens OX=9606 GN=XPOT PE=1 SV=2 6 3921.5 - 1.82E+06 - - - 0.0127 - 2.316 0.486 - 397.8 1 2 0 0 14 0 0 0 0.00E+00 0.00E+00 - - - 4.7381 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.21616.21616.2 0.00355 22-Dec R.FSPIPFPPLSYK.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1391.7489 11.44 53684 21616 2 1391.750089 696.8817 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3921.6 - 1.69E+06 - - - 0.8364 - 1.627 0.183 - 282 1 2 0 0.0012 12 0 0 0 8.83E+06 7.72E+05 - - - 1.673 1 230117_WJC_METTL3_WT_vs_EV_F06.21617.21617.2 0.000329 20-Oct R.LFEFAGYDVLR[166.11].L sp|P54136|SYRC_HUMAN 1 1338.6848 -1 53685 21617 2 1338.682354 670.3497 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3921.8 - 1.09E+06 - - - -1.7958 - 2.127 0.477 - 278.9 1 2 0 -0.0024 11 0 0 0 0.00E+00 0.00E+00 - - - 4.605 1 230117_WJC_METTL3_WT_vs_EV_F06.21620.21620.2 4.26E-07 26-Dec K.TYVLNPLAPEFIPR[166.11].A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1638.9009 -1 53688 21620 2 1638.904441 820.4577 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.66 3922.1 - 975901 - - - 2.1612 - 2.295 0.494 - 378.4 1 2 0 0.0035 14 0 0 0 0.00E+00 0.00E+00 - - - 4.7733 1 230117_WJC_METTL3_WT_vs_EV_F06.21627.21627.2 1.35E-05 20-Nov K.LDTSQWPLLLK[136.11].N "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1320.7533 -1 53695 21627 2 1320.75674 661.3839 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 5.84 3923 - 574075 - - - 2.6137 - 2.44 0.509 - 502.1 1 2 0 0.0035 11 0 0 0 0.00E+00 0.00E+00 - - - 5.2125 0.9554 230117_WJC_METTL3_WT_vs_EV_F06.21629.21629.2 2.24 Aug-32 R.LLSAIGTSAIMDSDLLK.L sp|O15047|SET1A_HUMAN 1 1746.9437 -1 53697 21629 2 1746.944272 874.4791 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.21 3923.3 - 264474 - - - 0.3057 - 0.974 0.088 - 89.7 1 2 0 0.0005 17 0 0 0 0.00E+00 0.00E+00 - - - -0.374 1 230117_WJC_METTL3_WT_vs_EV_F06.21635.21635.2 0.00021 20-Nov R.LFEFAGYDVLR.L sp|P54136|SYRC_HUMAN 1 1328.6765 -1 53702 21635 2 1328.680053 665.3455 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3923.9 - 4.29E+06 - - - 2.6831 - 2.415 0.511 - 452.9 1 2 0 0.0036 11 0 0 0 0.00E+00 0.00E+00 - - - 5.1993 1 230117_WJC_METTL3_WT_vs_EV_F06.21636.21636.2 1.98E-09 15/30 R.IIGATDSSGELMFLMK.W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1711.8525 -1 53703 21636 2 1711.856643 856.9335 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3924 - 2.22E+06 - - - 2.4319 - 3.455 0.652 - 471.1 1 2 0 0.0042 16 0 0 0 0.00E+00 0.00E+00 - - - 6.9035 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.21637.21637.2 0.015 16-Jul R.GYPTLLLFR.G sp|Q8NBS9|TXND5_HUMAN 1 1078.6175 2.12 53704 21637 2 1078.620418 540.316 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 8.75 3924.1 - 1.85E+06 - - - 2.6905 - 1.509 0.366 - 204.8 1 2 0 0.0029 9 0 0 0 8.15E+06 3.84E+06 - - - 2.9337 1 230117_WJC_METTL3_WT_vs_EV_F06.21639.21639.2 0.000462 13/18 R.VVTDLISLIR.Q sp|P38432|COIL_HUMAN 1 1127.6914 -1 53706 21639 2 1127.69573 564.853 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3924.3 - 1.71E+06 - - - 3.8308 - 2.275 0.477 - 655.8 1 2 0 0.0043 10 0 0 0 0.00E+00 0.00E+00 - - - 4.8572 1 230117_WJC_METTL3_WT_vs_EV_F06.21640.21640.2 0.00032 18-Oct R.VVTDLISLIR[166.11].Q sp|P38432|COIL_HUMAN 1 1137.6997 -1 53707 21640 2 1137.702896 569.8571 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3924.4 - 1.49E+06 - - - 2.8268 - 2.183 0.46 - 362.5 1 2 0 0.0032 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6167 0.8595 230117_WJC_METTL3_WT_vs_EV_F06.21643.21643.2 0.844 16-Aug N.VLIIGELLK.Q "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 996.6583 -1 53710 21643 2 996.661104 499.3364 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.97 3924.7 - 1.26E+06 - - - 2.7943 - 1.545 0.25 - 181.7 1 1 0 0.0028 9 0 0 0 0.00E+00 0.00E+00 - - - 2.1452 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.21644.21644.2 0.211 16-Jul R.FYELLVTGR.Y "sp|Q9UPS6|SET1B_HUMAN,tr|A0A0A0MQV9|A0A0A0MQV9_HUMAN" 2 1096.5917 -1 53711 21644 2 1096.595127 549.3031 Histone-lysine N-methyltransferase SETD1B OS=Homo sapiens OX=9606 GN=SETD1B PE=1 SV=3 6 3924.8 - 1.09E+06 - - - 3.1288 - 1.574 0.222 - 165.9 1 2 0 0.0034 9 0 0 0 0.00E+00 0.00E+00 - - - 1.992 0.9965 230117_WJC_METTL3_WT_vs_EV_F06.21645.21645.2 0.00717 18-Nov K.AWLLSMIQSK[136.11].C "sp|Q9UBU9|NXF1_HUMAN,tr|E9PLA7|E9PLA7_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1183.6515 -1 53712 21645 2 1183.658029 592.833 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 8.8 3925 - 947782 - - - 5.5447 - 2.165 0.359 - 454.7 1 2 0 0.0066 10 0 0 0 0.00E+00 0.00E+00 - - - 3.8466 1 230117_WJC_METTL3_WT_vs_EV_F06.21648.21648.2 0.000343 18-Dec R.DAVLLLFANK.Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1102.6386 -1 53715 21648 2 1102.642954 552.3266 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3925.4 - 838312 - - - 3.907 - 2.519 0.49 - 744.4 1 2 0 0.0043 10 0 0 0 0.00E+00 0.00E+00 - - - 5.2376 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.21650.21650.2 0.00179 14-Sep R.AAFLNFFR.D sp|Q5JTZ9|SYAM_HUMAN 1 984.5181 -1 53717 21650 2 984.52035 493.2663 "Alanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=AARS2 PE=1 SV=1" 9.79 3925.6 - 775878 - - - 2.2478 - 1.594 0.424 - 310.9 1 2 0 0.0022 8 0 0 0 0.00E+00 0.00E+00 - - - 3.5781 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21656.21656.2 0.00452 18-Aug R.DAVLLLFANK[136.11].Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1110.6528 -1 53722 21656 2 1110.654512 556.3337 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3926.1 - 1.20E+06 - - - 1.5 - 1.908 0.358 - 261.2 1 2 0 0.0017 10 0 0 0 0.00E+00 0.00E+00 - - - 3.488 1 230117_WJC_METTL3_WT_vs_EV_F06.21657.21657.2 1.42E-07 20-Dec K.YPSPFFVFGEK.L sp|Q08211|DHX9_HUMAN 1 1316.6441 1 53723 21657 2 1316.645975 659.3293 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3926.2 - 1.13E+06 - - - 1.4051 - 2.304 0.594 - 607.4 1 2 0 0.0019 11 0 0 0 6.01E+07 5.99E+07 - - - 5.6856 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21658.21658.2 0.00104 20-Oct K.YPSPFFVFGEK[136.11].L sp|Q08211|DHX9_HUMAN 1 1324.6583 1 53724 21658 2 1324.659518 663.3364 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3926.2 - 1.05E+06 - - - 0.9006 - 2.063 0.469 - 373.3 1 2 0 0.0012 11 0 0 0 6.01E+07 5.99E+07 - - - 4.4637 1 230117_WJC_METTL3_WT_vs_EV_F06.21659.21659.2 0.00162 18-Nov R.DALLLIFANK.Q "sp|P36406|TRI23_HUMAN,sp|P62330|ARF6_HUMAN" 2 1116.6543 -1 53725 21659 2 1116.656198 559.3344 E3 ubiquitin-protein ligase TRIM23 OS=Homo sapiens OX=9606 GN=TRIM23 PE=1 SV=1 5.84 3926.3 - 704417 - - - 1.7033 - 2.46 0.414 - 378.3 1 2 0 0.0019 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6108 1 230117_WJC_METTL3_WT_vs_EV_F06.21660.21660.2 1.59E-09 19/30 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 0.91 53726 21660 2 1807.925102 904.9689 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3926.5 - 681548 - - - 1.0797 - 3.352 0.6 - 1144 1 2 0 0.002 16 0 0 0 2.50E+07 2.75E+07 - - - 6.4457 1 230117_WJC_METTL3_WT_vs_EV_F06.21662.21662.2 1.12E-08 22-Dec R.FSTFFDDAPVFR.L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1447.6772 -1 53728 21662 2 1447.678567 724.8459 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3926.6 - 602123 - - - 0.9332 - 2.404 0.652 - 558.2 1 2 0 0.0014 12 0 0 0 0.00E+00 0.00E+00 - - - 6.1641 1 230117_WJC_METTL3_WT_vs_EV_F06.21663.21663.2 2.87E-08 18/30 K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 0.91 53729 21663 2 1797.916222 899.9647 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3926.7 - 500527 - - - 0.7464 - 3.535 0.622 - 981.8 1 2 0 0.0013 16 0 0 0 2.50E+07 2.75E+07 - - - 6.7391 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21665.21665.2 0.00282 20-Oct R.FLEEFITPIVK.V "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 1334.7486 1.47 53731 21665 2 1334.750013 668.3816 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.53 3926.9 - 426511 - - - 1.0661 - 1.997 0.396 - 253.6 1 2 0 0.0014 11 0 0 0 2.55E+06 1.73E+06 - - - 3.8365 0.9925 230117_WJC_METTL3_WT_vs_EV_F06.21671.21671.2 0.131 20-May R.FLEEFITPIVK[136.11].V "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 1342.7628 -1 53737 21671 2 1342.765802 672.3887 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.53 3927.7 - 307678 - - - 2.2431 - 1.126 0.24 - 52.4 5 2 0 0.003 11 0 0 0 0.00E+00 0.00E+00 - - - 0.8215 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.21675.21675.2 0.00383 14-Jul R.GFGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 921.5204 1.13 53740 21675 2 921.520572 461.7675 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3928.1 - 5.89E+06 - - - 0.2138 - 1.382 0.488 - 142.9 1 2 0 0.0002 8 0 0 0 2.05E+08 1.82E+08 - - - 3.6211 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.21676.21676.2 0.000563 14-Aug R.GFGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 913.5062 1.13 53741 21676 2 913.506411 457.7604 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3928.2 - 5.25E+06 - - - 0.2583 - 1.497 0.463 - 206.1 1 2 0 0.0002 8 0 0 0 2.05E+08 1.82E+08 - - - 3.6775 1 230117_WJC_METTL3_WT_vs_EV_F06.21679.21679.2 1.11E-07 22-Nov R.FSTFFDDAPVFR[166.11].L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1457.6855 -1 53744 21679 2 1457.68713 729.85 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3928.4 - 1.45E+06 - - - 1.1278 - 2.06 0.598 - 384.1 1 2 0 0.0016 12 0 0 0 0.00E+00 0.00E+00 - - - 5.3589 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21683.21683.3 6.22E-05 Sep-60 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 1.04 53748 21683 3 1807.924187 603.6483 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3928.7 - 975860 - - - 0.5736 - 2.159 0.519 - 107.8 1 2 0 0.001 16 0 0 0 2.42E+06 2.33E+06 - - - 6.3009 1 230117_WJC_METTL3_WT_vs_EV_F06.21686.21686.2 5.11E-08 14/30 K.LFIGGLSFETTDDSLR[166.11].E "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1779.8918 -1 53751 21686 2 1779.893399 890.9532 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.03 3929.1 - 677769 - - - 0.8703 - 2.866 0.6 - 584.7 1 2 0 0.0015 16 0 0 0 0.00E+00 0.00E+00 - - - 6.0608 0.8748 230117_WJC_METTL3_WT_vs_EV_F06.21689.21689.2 3.95 14-Feb R.FWPIIQIR.L "sp|Q14999|CUL7_HUMAN,sp|Q8IWT3|CUL9_HUMAN,tr|A0A669KB95|A0A669KB95_HUMAN,tr|A0A669KAU7|A0A669KAU7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN,tr|E9PEZ1|E9PEZ1_HUMAN" 6 1071.6229 -1 53754 21689 2 1071.6231 536.8187 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 9.75 3929.3 - 507903 - - - 0.153 - 0.684 0.147 - 14.4 1 2 0 0.0002 8 0 0 0 0.00E+00 0.00E+00 - - - -1.0188 1 230117_WJC_METTL3_WT_vs_EV_F06.21694.21694.2 0.00359 20-Dec K.VTDLLGGLFSK.T "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1148.6441 2.41 53758 21694 2 1148.644997 575.3293 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.81 3929.9 - 2.30E+06 - - - 0.7592 - 2.63 0.489 - 726 1 2 0 0.0009 11 0 0 0 3.02E+07 1.25E+07 - - - 5.2684 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.21698.21698.2 0.000447 20-Oct R.IFGLLMGTLQK[136.11].F sp|Q9H307|PININ_HUMAN 1 1227.7141 1.24 53762 21698 2 1227.717631 614.8643 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3930.4 - 1.74E+06 - - - 2.9038 - 2.114 0.463 - 250.2 1 2 0 0.0036 11 0 0 0 2.24E+07 1.81E+07 - - - 4.4847 0.9853 230117_WJC_METTL3_WT_vs_EV_F06.21700.21700.2 0.00539 16-Oct K.GVIDLIFEK.A "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 1032.5855 1.23 53764 21700 2 1032.589223 517.3001 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 3930.6 - 1.09E+06 - - - 3.559 - 1.773 0.025 - 307 1 2 0 0.0037 9 0 0 0 2.36E+06 1.91E+06 - - - 0.8813 1 230117_WJC_METTL3_WT_vs_EV_F06.21701.21701.2 0.00234 18/24 N.IVGLVGVDQFLVK.T sp|P13639|EF2_HUMAN 1 1385.8282 -1 53765 21701 2 1385.831194 693.9214 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3930.7 - 3.02E+06 - - - 2.133 - 2.894 0.522 - 1040.7 1 1 0 0.003 13 0 0 0 0.00E+00 0.00E+00 - - - 5.6229 0.9831 230117_WJC_METTL3_WT_vs_EV_F06.21704.21704.2 0.393 16-Aug K.LLELDSFLK.E "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|K9J957|K9J957_HUMAN,tr|B7Z8D3|B7Z8D3_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 5 1076.6118 -1 53768 21704 2 1076.616439 539.3132 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.37 3931.1 - 601867 - - - 4.3442 - 1.375 0.165 - 134.8 1 2 0 0.0047 9 0 0 0 0.00E+00 0.00E+00 - - - 1.1795 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.21705.21705.2 0.0157 20-Dec R.TPGGVFLNLLK[136.11].N sp|Q9H814|PHAX_HUMAN 1 1165.695 0.71 53769 21705 2 1165.698345 583.8548 Phosphorylated adapter RNA export protein OS=Homo sapiens OX=9606 GN=PHAX PE=1 SV=1 8.41 3931.3 - 482014 - - - 2.8309 - 1.618 0.338 - 297.3 1 2 0 0.0033 11 0 0 0 2.40E+06 3.37E+06 - - - 2.8382 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.21706.21706.2 0.00783 18-Sep K.SLESFVELMK.T sp|Q6KB66|K2C80_HUMAN 1 1181.6002 -1 53770 21706 2 1181.60402 591.8074 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 4.53 3931.4 - 477982 - - - 3.2236 - 2.027 0.389 - 179.3 1 2 0 0.0038 10 0 0 0 0.00E+00 0.00E+00 - - - 3.8852 0.999 230117_WJC_METTL3_WT_vs_EV_F06.21707.21707.2 0.000589 22-Oct R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 -1 53771 21707 2 1603.770152 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3931.5 - 467560 - - - 3.8734 - 1.873 0.463 - 277.8 1 2 0 0.0062 12 0 0 0 0.00E+00 0.00E+00 - - - 4.1099 0.9895 230117_WJC_METTL3_WT_vs_EV_F06.21711.21711.2 0.0663 14-Jun R.FWPIIQIR[166.11].L "sp|Q14999|CUL7_HUMAN,sp|Q8IWT3|CUL9_HUMAN,tr|A0A669KB95|A0A669KB95_HUMAN,tr|A0A669KAU7|A0A669KAU7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN,tr|E9PEZ1|E9PEZ1_HUMAN" 6 1081.6312 -1 53775 21711 2 1081.634944 541.8229 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 9.75 3932 - 347146 - - - 3.4559 - 1.287 0.174 - 107.6 1 2 0 0.0037 8 0 0 0 0.00E+00 0.00E+00 - - - 1.086 1 230117_WJC_METTL3_WT_vs_EV_F06.21713.21713.2 3.30E-09 14/30 R.IMEGPAFNFLDAPAVR.V sp|P11177|ODPB_HUMAN 1 1746.8763 10.09 53777 21713 2 1746.884194 874.4454 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 4.37 3932.3 - 335242 - - - 4.5035 - 2.99 0.586 - 596.6 1 2 0 0.0079 16 0 0 0 1.97E+06 1.95E+05 - - - 6.0595 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21716.21716.2 0.000415 20-Oct K.FIWSEISYLSK.W sp|Q16706|MA2A1_HUMAN 1 1371.7075 1.25 53779 21716 2 1371.71024 686.861 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 6 3932.6 - 216119 - - - 2.031 - 1.78 0.412 - 281.3 1 2 0 0.0028 11 0 0 0 1.34E+06 1.07E+06 - - - 3.643 1 230117_WJC_METTL3_WT_vs_EV_F06.21720.21720.2 0.000626 12-Sep G.FGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 864.4989 0.95 53783 21720 2 864.498971 433.2567 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3933.1 - 532342 - - - 0.0694 - 1.895 0.504 - 194.9 1 1 0 0.0001 7 0 0 0 1.71E+06 1.80E+06 - - - 4.7889 1 230117_WJC_METTL3_WT_vs_EV_F06.21722.21722.2 0.00426 13/24 N.IVGLVGVDQFLVK[136.11].T sp|P13639|EF2_HUMAN 1 1393.8424 -1 53785 21722 2 1393.843154 697.9285 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3933.3 - 426017 - - - 0.5137 - 2.521 0.486 - 539.5 1 1 0 0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 5.0035 0.998 230117_WJC_METTL3_WT_vs_EV_F06.21724.21724.2 0.0352 20-Jul R.FLDELDAVQMD.- "sp|O15160|RPAC1_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 3 1294.5751 - 53787 21724 2 1294.576083 648.2948 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 3.59 3933.5 - 416184 - - - 0.7446 - 1.321 0.269 - 125.2 1 2 0 0.001 11 0 0 0 - - - - - 1.7806 0.9979 230117_WJC_METTL3_WT_vs_EV_F06.21725.21725.2 0.0195 18-Dec K.FLLLQGLVEK.E "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 1158.7012 1.13 53788 21725 2 1158.698478 580.3579 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 6 3933.6 - 391398 - - - -2.3889 - 2.199 0.372 - 516.5 1 2 0 -0.0028 10 0 0 0 5.28E+06 4.69E+06 - - - 3.9873 0.9735 230117_WJC_METTL3_WT_vs_EV_F06.21726.21726.2 0.00317 12-Aug G.FGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 856.4847 0.98 53789 21726 2 856.485261 429.2496 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3933.8 - 342666 - - - 0.6422 - 1.732 0.445 - 177.9 1 1 0 0.0006 7 0 0 0 1.76E+06 1.80E+06 - - - 4.068 0.9951 230117_WJC_METTL3_WT_vs_EV_F06.21727.21727.2 0.155 26-Jun R.ILLDIDNDTESTAL.- sp|Q68EM7|RHG17_HUMAN 1 1531.7617 - 53790 21727 2 1531.761498 766.8881 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 3.37 3933.9 - 210583 - - - -0.1541 - 1.068 0.292 - 81.6 1 2 0 -0.0002 14 0 0 0 - - - - - 1.3627 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.21734.21734.2 0.0146 18-Sep K.IATLISSFLK.E "sp|O95394|AGM1_HUMAN,tr|A0A494C1E2|A0A494C1E2_HUMAN,tr|J3KN95|J3KN95_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C1Q4|A0A494C1Q4_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|A0A087WT27|A0A087WT27_HUMAN" 7 1091.659 2.01 53796 21734 2 1091.65874 546.8368 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 8.75 3934.9 - 288270 - - - -0.2812 - 1.675 0.295 - 146.7 1 2 0 -0.0003 10 0 0 0 1.53E+06 7.63E+05 - - - 2.6596 0.9939 230117_WJC_METTL3_WT_vs_EV_F06.21738.21738.2 0.107 12-Jun K.ELFSFFR.D "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 944.4756 1.98 53800 21738 2 944.476398 473.2451 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6.1 3935.3 - 1.06E+06 - - - 0.8417 - 1.371 0.112 - 155.7 1 2 0 0.0008 7 0 0 0 3.36E+06 1.70E+06 - - - 0.8678 0.8886 230117_WJC_METTL3_WT_vs_EV_F06.21739.21739.2 0.00518 22-Sep R.SVLDAAQIVGLN.C sp|Q92598|HS105_HUMAN 1 1198.6558 - 53801 21739 2 1198.656748 600.3352 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 3.8 3935.4 - 1.02E+06 - - - 0.8309 - 1.668 0.217 - 113.6 1 1 0 0.001 12 0 0 0 - - - - - 1.9896 0.9628 230117_WJC_METTL3_WT_vs_EV_F06.21745.21745.2 3.08 22-Jul K.YDNMAELFAVVK.T "sp|Q9UK41|VPS28_HUMAN,tr|E9PR04|E9PR04_HUMAN,tr|E9PQR7|E9PQR7_HUMAN,tr|E9PM90|E9PM90_HUMAN" 4 1398.6853 -1 53807 21745 2 1398.687134 700.3499 Vacuolar protein sorting-associated protein 28 homolog OS=Homo sapiens OX=9606 GN=VPS28 PE=1 SV=1 4.37 3936.2 - 627549 - - - 1.2841 - 1.085 0.046 - 61.8 1 2 0 0.0018 12 0 0 0 0.00E+00 0.00E+00 - - - -0.4052 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.21747.21747.3 0.199 13/56 K.GLAPDLPEDLYHLIK.K "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1692.9087 1.75 53809 21747 3 1692.911445 565.3102 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 4.54 3936.4 - 434378 - - - 1.6374 - 2.154 0.193 - 193.8 1 2 0 0.0028 15 0 0 0 1.80E+06 1.03E+06 - - - 2.6932 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.21752.21752.2 0.0345 26-Aug K.MGIYYIPVLGPAPR[166.11].W sp|Q9BSC4|NOL10_HUMAN 1 1555.846 -1 53814 21752 2 1555.845837 778.9303 Nucleolar protein 10 OS=Homo sapiens OX=9606 GN=NOL10 PE=1 SV=1 8.34 3937 - 229067 - - - -0.1215 - 1.559 0.22 - 144.6 1 2 0 -0.0002 14 0 0 0 0.00E+00 0.00E+00 - - - 1.7802 1 230117_WJC_METTL3_WT_vs_EV_F06.21756.21756.2 1.35E-09 15/22 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 1462.28 53816 21756 2 1459.797977 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3937.5 - 5.64E+06 - - - 3.9259 - 3.024 0.568 - 1067.9 1 2 0 0.0057 12 0 0 0 3.96E+08 2.71E+05 - - - 6.146 0.9971 230117_WJC_METTL3_WT_vs_EV_F06.21757.21757.2 5.18 20-Dec K.LALGIPLPELR.N "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1190.7387 2.43 53817 21757 2 1190.744429 596.3766 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3937.5 - 1.55E+06 - - - 4.8163 - 2.57 0.234 - 406.9 1 2 0 0.0057 11 0 0 0 1.84E+07 7.58E+06 - - - 3.321 0.9953 230117_WJC_METTL3_WT_vs_EV_F06.21760.21760.2 0.00506 15/20 K.LALGIPLPELR[166.11].N "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1200.747 2.43 53820 21760 2 1200.752262 601.3808 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3937.9 - 691205 - - - 4.4123 - 2.395 0.132 - 710.3 1 2 0 0.0053 11 0 0 0 1.84E+07 7.58E+06 - - - 2.377 0.9998 230117_WJC_METTL3_WT_vs_EV_F06.21765.21765.3 7.00E-07 18/44 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 43.51 53825 21765 3 1459.798682 487.6047 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3938.5 - 468436 - - - 4.4088 - 3.097 0.45 - 627.2 1 2 0 0.0064 12 0 0 0 2.90E+07 6.66E+05 - - - 6.6887 0.9392 230117_WJC_METTL3_WT_vs_EV_F06.21766.21766.2 1.1 20-Oct K.LWALQDFSC[160.03]LK[136.11].T "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 1387.705 -1 53826 21766 2 1387.711006 694.8598 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.83 3938.6 - 430966 - - - 4.3583 - 1.383 0.043 - 244.9 1 2 0 0.006 11 0 0 0 0.00E+00 0.00E+00 - - - 0.2339 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21773.21773.2 0.000146 20-Sep K.VVLPTFILEPR.S "sp|Q9BZF1|OSBL8_HUMAN,tr|F8VUA7|F8VUA7_HUMAN,tr|F8VQX7|F8VQX7_HUMAN" 3 1282.7649 1.7 53833 21773 2 1282.768149 642.3897 Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3 5.97 3939.5 - 322197 - - - 2.5258 - 2.082 0.466 - 298.8 1 2 0 0.0032 11 0 0 0 2.97E+06 1.74E+06 - - - 4.4657 1 230117_WJC_METTL3_WT_vs_EV_F06.21777.21777.2 8.08E-07 18-Nov K.ADLTALFLPR[166.11].Q sp|Q13045|FLII_HUMAN 1 1125.6422 2.04 53836 21777 2 1125.648339 563.8284 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.88 3940 - 1.23E+06 - - - 5.4849 - 2.487 0.503 - 330.4 1 2 0 0.0062 10 0 0 0 9.44E+06 4.63E+06 - - - 5.2973 1 230117_WJC_METTL3_WT_vs_EV_F06.21779.21779.3 9.86E-09 17/60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 28.05 53838 21779 3 1796.011088 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3940.1 - 7.06E+06 - - - 3.7439 - 3.305 0.599 - 508.4 1 2 0 0.0067 16 0 0 0 1.43E+07 5.09E+05 - - - 8.2837 1 230117_WJC_METTL3_WT_vs_EV_F06.21780.21780.2 6.91E-07 18-Dec K.ADLTALFLPR.Q sp|Q13045|FLII_HUMAN 1 1115.6339 2.03 53839 21780 2 1115.637797 558.8242 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.88 3940.2 - 2.61E+06 - - - 3.4976 - 2.649 0.522 - 524.1 1 2 0 0.0039 10 0 0 0 9.41E+06 4.63E+06 - - - 5.6145 1 230117_WJC_METTL3_WT_vs_EV_F06.21781.21781.2 1.06E-05 13/22 K.ITVNEVELLVMK.A "sp|Q9UNM6|PSD13_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 2 1386.7792 -1 53840 21781 2 1386.785939 694.3969 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 4.53 3940.2 - 2.06E+06 - - - 4.8313 - 2.983 0.49 - 656.2 1 2 0 0.0067 12 0 0 0 0.00E+00 0.00E+00 - - - 5.5337 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.21784.21784.2 0.00023 20-Dec K.AIVEFLSNLAR.H sp|Q13112|CAF1B_HUMAN 1 1231.6925 1.84 53843 21784 2 1231.69535 616.8535 Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1 6.05 3940.5 - 1.42E+06 - - - 2.3366 - 2.403 0.251 - 499.7 1 2 0 0.0029 11 0 0 0 4.15E+06 2.26E+06 - - - 3.2657 1 230117_WJC_METTL3_WT_vs_EV_F06.21786.21786.2 3.55E-07 20/30 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 -1 53845 21786 2 1796.008623 899.0095 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3940.7 - 1.25E+06 - - - 2.3714 - 3.881 0.653 - 1459.4 1 2 0 0.0043 16 0 0 0 0.00E+00 0.00E+00 - - - 7.1967 1 230117_WJC_METTL3_WT_vs_EV_F06.21787.21787.2 1.97E-05 13/22 K.ITVNEVELLVMK[136.11].A "sp|Q9UNM6|PSD13_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 2 1394.7934 1.8 53846 21787 2 1394.798503 698.404 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 4.53 3940.9 - 1.06E+06 - - - 3.6306 - 2.922 0.465 - 689 1 2 0 0.0051 12 0 0 0 5.50E+06 3.06E+06 - - - 5.2952 0.9806 230117_WJC_METTL3_WT_vs_EV_F06.21788.21788.2 0.0304 20-Nov K.AIVEFLSNLAR[166.11].H sp|Q13112|CAF1B_HUMAN 1 1241.7007 -1 53847 21788 2 1241.709802 621.8576 Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1 6.05 3941 - 891967 - - - 7.2964 - 1.806 0.305 - 449.5 1 2 0 0.0091 11 0 0 0 0.00E+00 0.00E+00 - - - 2.89 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.21792.21792.2 0.0653 20-Sep K.VVLPTFILEPR[166.11].S "sp|Q9BZF1|OSBL8_HUMAN,tr|F8VUA7|F8VUA7_HUMAN,tr|F8VQX7|F8VQX7_HUMAN" 3 1292.7732 1.7 53851 21792 2 1292.777338 647.3939 Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3 5.97 3941.5 - 692921 - - - 3.2171 - 1.948 0.432 - 245.7 1 2 0 0.0042 11 0 0 0 2.97E+06 1.74E+06 - - - 4.0343 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.21802.21802.2 1.21 16-Nov R.DILALMEVK.M sp|Q96EK4|THA11_HUMAN 1 1030.5733 2.07 53860 21802 2 1030.575406 516.2939 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 4.37 3942.6 - 1.21E+06 - - - 2.0746 - 2.1 0.191 - 353 1 2 0 0.0021 9 0 0 0 3.20E+06 1.55E+06 - - - 2.5975 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.21807.21807.2 0.182 14-Jun R.DFC[160.03]FFTIK[136.11].F "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1084.5143 -1 53865 21807 2 1084.516538 543.2644 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.83 3943.1 - 584364 - - - 2.0599 - 1.145 0.265 - 77.4 1 2 0 0.0022 8 0 0 0 0.00E+00 0.00E+00 - - - 1.406 1 230117_WJC_METTL3_WT_vs_EV_F06.21808.21808.3 0.00934 16/72 K.VLLVGADNFTLLGKPLLGK.D "sp|Q7Z2W9|RM21_HUMAN,tr|H3BUY0|H3BUY0_HUMAN" 2 1967.1819 -1 53866 21808 3 1967.187136 656.7346 "39S ribosomal protein L21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL21 PE=1 SV=2" 8.56 3943.2 - 542716 - - - 2.6439 - 3.187 0.522 - 286.1 1 2 0 0.0052 19 0 0 0 0.00E+00 0.00E+00 - - - 7.206 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.21810.21810.2 0.000422 16-Sep R.NLPFDFTWK.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1166.576 2.72 53868 21810 2 1166.578129 584.2953 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3943.5 - 453571 - - - 1.7856 - 1.676 0.248 - 219 1 2 0 0.0021 9 0 0 0 1.53E+08 5.62E+07 - - - 2.3661 1 230117_WJC_METTL3_WT_vs_EV_F06.21820.21820.2 8.96E-07 15/26 K.LYSPSQIGAFVLMK.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1552.8323 4.84 53877 21820 2 1552.836481 777.4234 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3944.8 - 9.36E+06 - - - 2.6687 - 2.916 0.608 - 747 1 2 0 0.0041 14 0 0 0 5.34E+07 1.10E+07 - - - 6.216 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21821.21821.3 1.35E-07 16/52 K.LYSPSQIGAFVLMK.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1552.8323 3.94 53878 21821 3 1552.837094 518.6181 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3944.9 - 3.77E+06 - - - 3.0634 - 2.94 0.541 - 450.1 1 2 0 0.0048 14 0 0 0 1.35E+07 3.44E+06 - - - 7.4362 0.9978 230117_WJC_METTL3_WT_vs_EV_F06.21822.21822.2 0.196 24-Oct R.LLDISASSTEQIL.- "sp|O43615|TIM44_HUMAN,tr|M0QXM9|M0QXM9_HUMAN" 2 1388.7399 - 53879 21822 2 1388.745346 695.3772 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.67 3944.9 - 2.43E+06 - - - 3.9388 - 1.827 0.309 - 304.9 1 2 0 0.0055 13 0 0 0 - - - - - 2.8683 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.21823.21823.2 0.00949 22-Sep R.VALILQNVDLPN.- "sp|Q04446|GLGB_HUMAN,tr|E9PGM4|E9PGM4_HUMAN" 2 1307.7449 - 53880 21823 2 1307.748434 654.8797 "1,4-alpha-glucan-branching enzyme OS=Homo sapiens OX=9606 GN=GBE1 PE=1 SV=3" 3.8 3945 - 1.59E+06 - - - 2.7008 - 1.859 0.396 - 155.4 1 2 0 0.0035 12 0 0 0 - - - - - 3.5962 1 230117_WJC_METTL3_WT_vs_EV_F06.21824.21824.2 0.00101 20-Nov K.DFAPVIVEAFK.H "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1234.6598 -1 53881 21824 2 1234.662367 618.3372 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.37 3945.1 - 1.40E+06 - - - 2.0994 - 2.128 0.513 - 358.7 1 2 0 0.0026 11 0 0 0 0.00E+00 0.00E+00 - - - 4.8722 0.9941 230117_WJC_METTL3_WT_vs_EV_F06.21825.21825.2 0.529 14-Jul K.ISLIQIFR[166.11].A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 998.6152 -1 53882 21825 2 998.618189 500.3149 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.75 3945.2 - 1.18E+06 - - - 2.9711 - 1.722 0.113 - 128 3 2 0 0.003 8 0 0 0 0.00E+00 0.00E+00 - - - 1.3007 1 230117_WJC_METTL3_WT_vs_EV_F06.21826.21826.2 1.27E-05 16/28 R.VLAFLSSVAGDALTR[166.11].H sp|Q92616|GCN1_HUMAN 1 1528.8489 -1 53883 21826 2 1528.85442 765.4317 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3945.3 - 1.11E+06 - - - 3.6348 - 3.087 0.591 - 985.5 1 2 0 0.0056 15 0 0 0 0.00E+00 0.00E+00 - - - 6.1757 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21827.21827.3 2.32E-07 14/56 R.VLAFLSSVAGDALTR.H sp|Q92616|GCN1_HUMAN 1 1518.8406 0.71 53884 21827 3 1518.846595 507.2875 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3945.4 - 991290 - - - 3.9517 - 2.667 0.521 - 303.8 1 2 0 0.006 15 0 0 0 1.50E+06 2.11E+06 - - - 6.9066 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.21828.21828.2 0.000444 18-Oct R.LLELQYFISR[166.11].D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1290.7211 -1 53885 21828 2 1290.726056 646.3678 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 6 3945.5 - 870311 - - - 3.8064 - 2.177 0.391 - 467.9 1 2 0 0.0049 10 0 0 0 0.00E+00 0.00E+00 - - - 4.0989 1 230117_WJC_METTL3_WT_vs_EV_F06.21831.21831.2 0.0154 16/26 K.QIALAVLSTELAVR.K "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1482.877 -1 53888 21831 2 1482.88108 742.4458 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3945.9 - 708301 - - - 2.7656 - 2.804 0.41 - 1100.8 1 2 0 0.0041 14 0 0 0 0.00E+00 0.00E+00 - - - 4.6553 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.21832.21832.2 0.0457 24-Oct R.NIIGVIPYFPYSK.Q "sp|Q14558|KPRA_HUMAN,tr|C9JKT9|C9JKT9_HUMAN,tr|B4DP31|B4DP31_HUMAN,tr|C9JNQ3|C9JNQ3_HUMAN,tr|C9JUN4|C9JUN4_HUMAN,tr|C9J168|C9J168_HUMAN" 6 1509.8232 -1 53889 21832 2 1509.827543 755.9189 Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Homo sapiens OX=9606 GN=PRPSAP1 PE=1 SV=2 8.5 3946 - 684541 - - - 2.9083 - 1.937 0.3 - 256.1 1 2 0 0.0044 13 0 0 0 0.00E+00 0.00E+00 - - - 2.9523 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.21833.21833.2 0.00802 18-Oct R.LLELQYFISR.D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1280.7129 -1 53890 21833 2 1280.716931 641.3637 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 6 3946.1 - 654998 - - - 3.1685 - 2.141 0.364 - 382.1 1 2 0 0.0041 10 0 0 0 0.00E+00 0.00E+00 - - - 3.8532 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.21835.21835.2 0.0184 26-Oct K.LAGLVEELEADEWR.F "sp|Q96DE5|APC16_HUMAN,tr|A0A087WUN5|A0A087WUN5_HUMAN" 2 1628.8046 -1 53892 21835 2 1628.806047 815.4096 Anaphase-promoting complex subunit 16 OS=Homo sapiens OX=9606 GN=ANAPC16 PE=1 SV=1 3.91 3946.4 - 613379 - - - 0.8872 - 1.428 0.28 - 140.3 1 2 0 0.0014 14 0 0 0 0.00E+00 0.00E+00 - - - 2.0027 0.999 230117_WJC_METTL3_WT_vs_EV_F06.21836.21836.2 0.0056 24-Oct R.NIFPSNLVSAAFR.S "sp|Q15758|AAAT_HUMAN,tr|M0QXM4|M0QXM4_HUMAN,tr|M0QX44|M0QX44_HUMAN" 3 1434.7619 1.65 53893 21836 2 1434.767616 718.3883 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 9.75 3946.5 - 596815 - - - 3.9498 - 2.175 0.421 - 262.4 1 2 0 0.0057 13 0 0 0 4.66E+06 2.82E+06 - - - 4.143 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21839.21839.2 0.00021 20-Nov K.DFAPVIVEAFK[136.11].H "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1242.674 -1 53895 21839 2 1242.67639 622.3443 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.37 3946.8 - 2.98E+06 - - - 1.9434 - 2.004 0.465 - 365.2 1 2 0 0.0024 11 0 0 0 0.00E+00 0.00E+00 - - - 4.3553 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21841.21841.2 0.000153 16-Oct R.NLPFDFTWK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1174.5902 2.72 53897 21841 2 1174.59169 588.3024 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3947 - 5.73E+06 - - - 1.2294 - 1.786 0.488 - 275.9 1 2 0 0.0014 9 0 0 0 1.53E+08 5.62E+07 - - - 4.3228 1 230117_WJC_METTL3_WT_vs_EV_F06.21842.21842.2 5.79E-09 17/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 4.47 53898 21842 2 1591.949353 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3947.1 - 4.89E+06 - - - 2.735 - 2.957 0.637 - 661.8 1 2 0 0.0044 15 0 0 0 1.33E+08 2.97E+07 - - - 6.41 1 230117_WJC_METTL3_WT_vs_EV_F06.21843.21843.3 1.68E-06 16/48 K.LFYADHPFIFLVR.D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1636.8766 3.27 53899 21843 3 1636.881748 546.6328 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3947.1 - 4.42E+06 - - - 3.1542 - 3.155 0.569 - 278.1 1 2 0 0.0052 13 0 0 0 2.50E+07 7.64E+06 - - - 7.9976 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21844.21844.3 7.07E-05 14/56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 4.81 53900 21844 3 1591.949388 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3947.2 - 2.79E+06 - - - 2.757 - 2.726 0.458 - 200.9 1 2 0 0.0044 15 0 0 0 6.68E+07 1.39E+07 - - - 6.2618 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.21847.21847.2 2.73E-05 22-Oct R.TLITFAGMIPYR.T "sp|Q8N1F7|NUP93_HUMAN,tr|H3BV15|H3BV15_HUMAN" 2 1381.7428 -1 53903 21847 2 1381.747192 691.8787 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 8.41 3947.4 - 1.61E+06 - - - 3.1837 - 2.375 0.306 - 353 1 2 0 0.0044 12 0 0 0 0.00E+00 0.00E+00 - - - 3.5757 1 230117_WJC_METTL3_WT_vs_EV_F06.21850.21850.2 5.56E-09 17/24 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 -1 53906 21850 2 1509.892155 755.9512 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3947.6 - 1.08E+06 - - - 2.8327 - 3.129 0.604 - 1036.5 1 2 0 0.0043 13 0 0 0 0.00E+00 0.00E+00 - - - 6.4285 1 230117_WJC_METTL3_WT_vs_EV_F06.21852.21852.2 3.37E-11 15/26 R.FGDPEC[160.03]QVILPLLK.S sp|P22102|PUR2_HUMAN 1 1627.8644 -1 53908 21852 2 1627.870124 814.9395 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.37 3947.9 - 856096 - - - 3.5378 - 3.321 0.693 - 623.1 1 2 0 0.0058 14 0 0 0 0.00E+00 0.00E+00 - - - 7.1697 1 230117_WJC_METTL3_WT_vs_EV_F06.21853.21853.2 2.87E-05 22-Dec K.LLPLVSDEVFIR.D sp|P11216|PYGB_HUMAN 1 1399.8075 8.39 53909 21853 2 1399.812541 700.911 "Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB PE=1 SV=5" 4.37 3948 - 816806 - - - 3.5998 - 2.251 0.496 - 531.5 1 2 0 0.005 12 0 0 0 3.85E+06 4.59E+05 - - - 4.8377 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21855.21855.3 2.17E-05 16/56 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 4.81 53911 21855 3 1601.95731 534.9917 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3948.2 - 720904 - - - 2.5225 - 2.838 0.469 - 242.8 1 2 0 0.004 15 0 0 0 6.68E+07 1.39E+07 - - - 6.4896 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.21856.21856.2 0.00338 18-Nov K.LLELQELVLR.L "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|A0A087WYC0|A0A087WYC0_HUMAN" 3 1224.7442 6.5 53912 21856 2 1224.747562 613.3794 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 4.53 3948.3 - 713150 - - - 2.7663 - 2.429 0.324 - 420.3 1 2 0 0.0034 10 0 0 0 1.95E+07 3.00E+06 - - - 3.9102 1 230117_WJC_METTL3_WT_vs_EV_F06.21857.21857.2 0.0675 17/28 R.ALVEVLGPYEPLLSR.V "sp|Q86VR2|RETR3_HUMAN,tr|K7EMF4|K7EMF4_HUMAN,tr|K7ELM8|K7ELM8_HUMAN,tr|K7EJ34|K7EJ34_HUMAN,tr|K7ENF4|K7ENF4_HUMAN,tr|K7ENZ6|K7ENZ6_HUMAN" 6 1654.9294 -1 53913 21857 2 1654.934579 828.472 Reticulophagy regulator 3 OS=Homo sapiens OX=9606 GN=RETREG3 PE=1 SV=1 4.53 3948.4 - 680440 - - - 3.1246 - 3.148 0.423 - 882.2 1 2 0 0.0052 15 0 0 0 0.00E+00 0.00E+00 - - - 4.983 1 230117_WJC_METTL3_WT_vs_EV_F06.21858.21858.2 8.26E-10 16/32 R.AIGLSPMSFPTADLTLK[136.11].M "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1768.9525 -1 53914 21858 2 1768.957989 885.4835 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.88 3948.5 - 637353 - - - 3.1267 - 3.187 0.623 - 786.7 1 2 0 0.0055 17 0 0 0 0.00E+00 0.00E+00 - - - 6.4904 1 230117_WJC_METTL3_WT_vs_EV_F06.21862.21862.2 0.000271 14/24 R.NVIVLQTVLQEVR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1519.8961 -1 53917 21862 2 1519.897633 760.9554 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3949 - 7.30E+06 - - - 0.977 - 2.78 0.524 - 733.4 1 2 0 0.0015 13 0 0 0 0.00E+00 0.00E+00 - - - 5.5349 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21863.21863.2 1.81E-05 20-Oct K.SVFGGLVNYFK.S "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1229.6445 -1 53918 21863 2 1229.645639 615.8295 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 8.31 3949 - 6.33E+06 - - - 0.9596 - 2.049 0.473 - 250.7 1 2 0 0.0012 11 0 0 0 0.00E+00 0.00E+00 - - - 4.4748 1 230117_WJC_METTL3_WT_vs_EV_F06.21865.21865.2 1.33E-09 15/30 L.SLGLETAGGVMTALIK.R "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1559.8593 8.9 53920 21865 2 1559.861192 780.9369 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.72 3949.1 - 3.54E+06 - - - 1.2258 - 2.929 0.587 - 667.7 1 1 0 0.0019 16 0 0 0 7.73E+06 8.68E+05 - - - 6.0181 1 230117_WJC_METTL3_WT_vs_EV_F06.21866.21866.3 1.14E-06 15/48 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 -1 53921 21866 3 1509.888919 504.3032 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3949.2 - 3.39E+06 - - - 0.6895 - 2.957 0.595 - 419.2 1 2 0 0.001 13 0 0 0 0.00E+00 0.00E+00 - - - 8.1129 1 230117_WJC_METTL3_WT_vs_EV_F06.21870.21870.2 0.000215 14/24 R.IGLFYMDNDLITR.N "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN" 2 1569.7861 -1 53925 21870 2 1569.788931 785.9003 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.21 3949.4 - 2.33E+06 - - - 1.7939 - 2.926 0.604 - 850.3 1 2 0 0.0028 13 0 0 0 0.00E+00 0.00E+00 - - - 6.2568 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21872.21872.2 0.00156 16-Oct K.ILNIFGVIK.G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1015.643 -1 53927 21872 2 1015.643944 508.8288 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3949.5 - 1.70E+06 - - - 0.9265 - 2.13 0.357 - 239.9 1 2 0 0.0009 9 0 0 0 0.00E+00 0.00E+00 - - - 3.865 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21873.21873.2 0.00227 16-Sep K.ILNIFGVIK[136.11].G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1023.6572 -1 53928 21873 2 1023.657928 512.8359 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3949.6 - 1.42E+06 - - - 0.7082 - 2.064 0.394 - 188.9 1 2 0 0.0007 9 0 0 0 0.00E+00 0.00E+00 - - - 4.0473 1 230117_WJC_METTL3_WT_vs_EV_F06.21874.21874.2 2.64E-07 24-Nov K.MFVLDEADEMLSR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 11 1564.7141 -1 53929 21874 2 1564.712326 783.3643 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 3.92 3949.6 - 1.34E+06 - - - -1.1248 - 2.058 0.568 - 367 1 2 0 -0.0018 13 0 0 0 0.00E+00 0.00E+00 - - - 5.088 0.9986 230117_WJC_METTL3_WT_vs_EV_F06.21877.21877.2 0.0379 24-Sep K.LLLQGLMDSVEAK.Q "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN" 3 1415.7694 -1 53932 21877 2 1415.769775 708.892 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 4.37 3949.9 - 1.12E+06 - - - 0.2635 - 1.388 0.328 - 134.9 1 2 0 0.0004 13 0 0 0 0.00E+00 0.00E+00 - - - 2.305 1 230117_WJC_METTL3_WT_vs_EV_F06.21884.21884.2 3.57E-06 28-Dec K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 4.47 53938 21884 2 1601.954524 801.9839 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3950.4 - 1.05E+07 - - - 0.7834 - 2.641 0.564 - 375 1 2 0 0.0013 15 0 0 0 1.33E+08 2.97E+07 - - - 5.5939 1 230117_WJC_METTL3_WT_vs_EV_F06.21885.21885.2 2.66E-05 20-Dec K.ILDVEIIFNER[166.11].G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1369.7481 1.77 53939 21885 2 1369.752633 685.8813 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3950.5 - 5.49E+06 - - - 3.3189 - 2.367 0.463 - 588.3 1 2 0 0.0045 11 0 0 0 2.01E+07 1.13E+07 - - - 4.7902 1 230117_WJC_METTL3_WT_vs_EV_F06.21886.21886.2 3.74E-06 24-Dec K.LGAGTFQLDQWLR.A sp|P50219|MNX1_HUMAN 1 1503.7834 -1 53940 21886 2 1503.784863 752.899 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 5.84 3950.5 - 5.09E+06 - - - 0.9642 - 2.714 0.468 - 475.4 1 2 0 0.0015 13 0 0 0 0.00E+00 0.00E+00 - - - 5.0597 1 230117_WJC_METTL3_WT_vs_EV_F06.21887.21887.2 0.000255 15/24 R.VNILEVASGAVLR.S sp|Q12788|TBL3_HUMAN 1 1339.7823 -1 53941 21887 2 1339.781153 670.8985 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3950.6 - 4.78E+06 - - - -0.8934 - 2.773 0.411 - 630.3 1 2 0 -0.0012 13 0 0 0 0.00E+00 0.00E+00 - - - 4.6939 1 230117_WJC_METTL3_WT_vs_EV_F06.21889.21889.2 0.0184 13/24 R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 53943 21889 2 1349.791508 675.9026 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3950.7 - 3.51E+06 - - - 0.6579 - 2.685 0.419 - 481.1 1 2 0 0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 4.6704 1 230117_WJC_METTL3_WT_vs_EV_F06.21890.21890.2 0.241 13/22 K.SLVALLVETQMK.K "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1330.753 0.24 53944 21890 2 1330.754236 666.3838 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.72 3950.7 - 3.49E+06 - - - 0.9108 - 2.664 0.429 - 590 1 2 0 0.0012 12 0 0 0 7.26E+06 3.03E+07 - - - 4.7873 1 230117_WJC_METTL3_WT_vs_EV_F06.21891.21891.2 4.41E-06 26-Oct R.IVEPYVTWGFPNLK[136.11].S "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1669.8959 -1 53945 21891 2 1669.896693 835.9552 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6 3950.8 - 2.93E+06 - - - 0.4569 - 2.159 0.51 - 308.6 1 2 0 0.0008 14 0 0 0 0.00E+00 0.00E+00 - - - 4.739 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21893.21893.2 0.00419 26-Aug R.IVEPYVTWGFPNLK.S "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1661.8817 -1 53947 21893 2 1661.884709 831.9481 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6 3950.9 - 2.89E+06 - - - 1.7925 - 1.798 0.413 - 155.1 1 2 0 0.003 14 0 0 0 0.00E+00 0.00E+00 - - - 3.5627 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21894.21894.2 0.456 22-Dec K.IVILPDYLEIAR.D sp|P45974|UBP5_HUMAN 1 1413.8232 -1 53948 21894 2 1413.824233 707.9189 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 4.37 3950.9 - 2.83E+06 - - - 0.7646 - 2.284 0.443 - 405.9 1 2 0 0.0011 12 0 0 0 0.00E+00 0.00E+00 - - - 4.4858 1 230117_WJC_METTL3_WT_vs_EV_F06.21896.21896.2 5.39E-07 28-Dec K.YFDTVPVAAAMC[160.03]VLK[136.11].T sp|Q15393|SF3B3_HUMAN 1 1691.8506 -1 53950 21896 2 1691.853671 846.9326 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.83 3951.1 - 2.29E+06 - - - 1.7939 - 2.373 0.518 - 327 1 2 0 0.003 15 0 0 0 0.00E+00 0.00E+00 - - - 4.9906 1 230117_WJC_METTL3_WT_vs_EV_F06.21897.21897.2 1.78E-12 16/28 K.YFDTVPVAAAMC[160.03]VLK.T sp|Q15393|SF3B3_HUMAN 1 1683.8364 -1 53951 21897 2 1683.832999 842.9255 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.83 3951.2 - 2.04E+06 - - - -2.0412 - 3.037 0.66 - 618.9 1 2 0 -0.0034 15 0 0 0 0.00E+00 0.00E+00 - - - 6.6458 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.21898.21898.2 0.000301 24-Dec K.SIIGVIPYFPYSK.Q "sp|O60256|KPRB_HUMAN,tr|C9JJS3|C9JJS3_HUMAN,tr|C9JDU5|C9JDU5_HUMAN,tr|E7EPA1|E7EPA1_HUMAN,tr|E7EW35|E7EW35_HUMAN,tr|C9JDH0|C9JDH0_HUMAN,tr|C9K0K7|C9K0K7_HUMAN" 7 1482.8123 -1 53952 21898 2 1482.817178 742.4134 Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Homo sapiens OX=9606 GN=PRPSAP2 PE=1 SV=1 8.22 3951.2 - 2.01E+06 - - - 3.3214 - 2.021 0.411 - 534.9 1 2 0 0.0049 13 0 0 0 0.00E+00 0.00E+00 - - - 3.8809 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21900.21900.3 0.000159 Oct-48 R.VNILEVASGAVLR.S sp|Q12788|TBL3_HUMAN 1 1339.7823 -1 53954 21900 3 1339.78121 447.6014 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3951.4 - 1.82E+06 - - - -0.8509 - 2.309 0.385 - 222.3 1 2 0 -0.0011 13 0 0 0 0.00E+00 0.00E+00 - - - 5.1009 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21902.21902.3 1.51E-06 14/48 R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 53955 21902 3 1349.790445 450.9375 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3951.6 - 352995 - - - -0.1296 - 3.032 0.434 - 321.5 1 2 0 -0.0002 13 0 0 0 0.00E+00 0.00E+00 - - - 6.386 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21904.21904.2 0.00159 20-Nov K.GFLSGLLDNVK.Q "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1161.6394 -1 53957 21904 2 1161.641074 581.827 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.84 3951.8 - 5.35E+06 - - - 1.4634 - 2.266 0.342 - 328.3 1 2 0 0.0017 11 0 0 0 0.00E+00 0.00E+00 - - - 3.7794 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21905.21905.2 0.000291 20-Sep K.LILPELGPVFK[136.11].Q "sp|Q6P3W7|SCYL2_HUMAN,tr|H0YIK6|H0YIK6_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 1232.7624 0.74 53958 21905 2 1232.764569 617.3885 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6 3951.8 - 4.61E+06 - - - 1.7627 - 1.816 0.504 - 285.2 1 2 0 0.0022 11 0 0 0 1.93E+07 2.60E+07 - - - 4.3769 0.9009 230117_WJC_METTL3_WT_vs_EV_F06.21906.21906.2 2.6 24-Apr K.AFTYSSTLISHK[136.11]R[166.11].L sp|A8MUV8|ZN727_HUMAN 1 1527.8164 0.001 53959 21906 2 1527.821556 764.9155 Putative zinc finger protein 727 OS=Homo sapiens OX=9606 GN=ZNF727 PE=5 SV=3 9.99 3951.9 - 3.51E+06 - - - 3.344 - 0.932 0.081 - 41.4 1 2 0 0.0051 13 0 0 0 0.00E+00 2.21E+07 - - - -0.5431 1 230117_WJC_METTL3_WT_vs_EV_F06.21907.21907.2 0.000191 24-Dec R.IESILMSLPLTAR.W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1442.8167 -1 53960 21907 2 1442.81968 722.4156 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3951.9 - 2.79E+06 - - - 2.0744 - 2.353 0.486 - 598.5 1 2 0 0.003 13 0 0 0 0.00E+00 0.00E+00 - - - 4.8258 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.21909.21909.2 0.00052 20-Oct K.FVSISDLLVPK.D sp|P50395|GDIB_HUMAN 1 1216.7067 -1 53962 21909 2 1216.709323 609.3606 Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2 5.84 3952 - 2.14E+06 - - - 2.1353 - 1.616 0.448 - 226.2 1 2 0 0.0026 11 0 0 0 0.00E+00 0.00E+00 - - - 3.6475 1 230117_WJC_METTL3_WT_vs_EV_F06.21910.21910.2 6.34E-07 14/24 K.LAGFLDLTEQEFR.L "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 1537.7777 -1 53963 21910 2 1537.780935 769.8961 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.14 3952.1 - 2.06E+06 - - - 2.1303 - 2.982 0.526 - 913.6 1 2 0 0.0033 13 0 0 0 0.00E+00 0.00E+00 - - - 5.7292 1 230117_WJC_METTL3_WT_vs_EV_F06.21911.21911.2 0.000117 16-Oct R.LFIFETFC[160.03]R[166.11].L "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 12 1241.6142 -1 53964 21911 2 1241.616173 621.8144 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 5.99 3952.1 - 1.97E+06 - - - 1.5601 - 2.076 0.48 - 419.8 1 2 0 0.0019 9 0 0 0 0.00E+00 0.00E+00 - - - 4.6989 1 230117_WJC_METTL3_WT_vs_EV_F06.21912.21912.3 1.04E-06 17/60 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 1.27 53965 21912 3 1663.954156 555.6576 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3952.2 - 1.69E+06 - - - 1.9736 - 2.875 0.499 - 320.2 1 2 0 0.0033 16 0 0 0 5.61E+06 4.41E+06 - - - 6.8121 1 230117_WJC_METTL3_WT_vs_EV_F06.21915.21915.2 1.28E-05 13/22 R.ANLGVFSVFAPR[166.11].G "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1286.7011 -1 53968 21915 2 1286.702049 644.3578 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 9.79 3952.3 - 1.50E+06 - - - 0.7554 - 2.656 0.489 - 662.1 1 2 0 0.001 12 0 0 0 0.00E+00 0.00E+00 - - - 5.2226 1 230117_WJC_METTL3_WT_vs_EV_F06.21916.21916.2 1.69E-05 26-Nov K.LSPVVGAVYGPELY.A "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 7 1462.7708 - 53969 21916 2 1462.777599 732.3927 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4 3952.4 - 1.14E+06 - - - 4.6603 - 2.178 0.511 - 313.5 1 1 0 0.0068 14 0 0 0 - - - - - 4.7665 1 230117_WJC_METTL3_WT_vs_EV_F06.21917.21917.2 0.000177 26-Nov K.LDDIFEPVLIPEPK.L "sp|Q14008|CKAP5_HUMAN,tr|H0YEK7|H0YEK7_HUMAN,tr|H0YCF6|H0YCF6_HUMAN" 3 1623.876 -1 53970 21917 2 1623.880148 812.9453 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 3.92 3952.5 - 1.11E+06 - - - 2.5692 - 2.25 0.517 - 341.6 1 2 0 0.0042 14 0 0 0 0.00E+00 0.00E+00 - - - 4.8932 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21919.21919.3 5.60E-07 13/60 K.INEAIVAVQAIIADPK[136.11].T sp|Q9Y224|RTRAF_HUMAN 1 1671.9651 -1 53972 21919 3 1671.968894 558.329 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3952.6 - 1.04E+06 - - - 2.2859 - 2.284 0.503 - 127.5 1 2 0 0.0038 16 0 0 0 0.00E+00 0.00E+00 - - - 6.2661 0.999 230117_WJC_METTL3_WT_vs_EV_F06.21920.21920.2 0.0052 22-Nov K.GVNSYPSLFIFR[166.11].S "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0TB22|A0A7P0TB22_HUMAN,tr|A0A7P0Z4F2|A0A7P0Z4F2_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN,tr|E7EP04|E7EP04_HUMAN,tr|A0A7P0T9B7|A0A7P0T9B7_HUMAN,tr|A0A494C1G5|A0A494C1G5_HUMAN,tr|A0A7P0TB83|A0A7P0TB83_HUMAN" 10 1408.7379 -1 53973 21920 2 1408.741868 705.3762 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 8.75 3952.7 - 924295 - - - 2.8479 - 1.63 0.361 - 222.1 1 2 0 0.004 12 0 0 0 0.00E+00 0.00E+00 - - - 2.9916 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21921.21921.3 2.56E-05 14/48 R.IESILMSLPLTAR[166.11].W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1452.825 1.23 53974 21921 3 1452.827703 485.2823 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3952.7 - 923774 - - - 1.8901 - 2.767 0.426 - 270.3 1 2 0 0.0027 13 0 0 0 4.76E+06 3.86E+06 - - - 6.0482 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21924.21924.3 1.12E-05 14/48 R.IESILMSLPLTAR.W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1442.8167 1.19 53976 21924 3 1442.819479 481.9462 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3953.1 - 1.85E+06 - - - 1.9351 - 2.887 0.412 - 263.3 1 2 0 0.0028 13 0 0 0 4.60E+06 3.86E+06 - - - 6.0072 1 230117_WJC_METTL3_WT_vs_EV_F06.21929.21929.2 0.000479 20-Nov K.DVLLPWYNAYR[166.11].F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1418.7222 -1 53981 21929 2 1418.726909 710.3684 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3953.4 - 1.55E+06 - - - 3.315 - 2.25 0.519 - 417.8 1 2 0 0.0047 11 0 0 0 0.00E+00 0.00E+00 - - - 5.0666 1 230117_WJC_METTL3_WT_vs_EV_F06.21931.21931.2 3.31E-05 13/22 K.GVNSYPSLFIFR.S "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0TB22|A0A7P0TB22_HUMAN,tr|A0A7P0Z4F2|A0A7P0Z4F2_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN,tr|E7EP04|E7EP04_HUMAN,tr|A0A7P0T9B7|A0A7P0T9B7_HUMAN,tr|A0A494C1G5|A0A494C1G5_HUMAN,tr|A0A7P0TB83|A0A7P0TB83_HUMAN" 10 1398.7296 2.96 53983 21931 2 1398.732942 700.3721 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 8.75 3953.6 - 1.33E+06 - - - 2.3993 - 2.557 0.527 - 437.7 1 2 0 0.0034 12 0 0 0 8.29E+06 2.80E+06 - - - 5.4026 1 230117_WJC_METTL3_WT_vs_EV_F06.21941.21941.2 2.38E-08 18/30 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 -1 53993 21941 2 1663.954285 832.9827 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3954.7 - 547176 - - - 2.0511 - 3.469 0.507 - 1062.1 1 2 0 0.0034 16 0 0 0 0.00E+00 0.00E+00 - - - 5.8427 0.9914 230117_WJC_METTL3_WT_vs_EV_F06.21942.21942.2 7.07 12-Aug K.EVLLEVK.Y "sp|Q13884|SNTB1_HUMAN,sp|Q13425|SNTB2_HUMAN,tr|A0A3B3ITC2|A0A3B3ITC2_HUMAN,tr|H0YCS0|H0YCS0_HUMAN" 4 828.4957 -1 53994 21942 2 828.498185 415.2551 Beta-1-syntrophin OS=Homo sapiens OX=9606 GN=SNTB1 PE=1 SV=3 4.53 3954.8 - 532767 - - - 3.0356 - 1.75 0.03 - 225.3 1 2 0 0.0025 7 0 0 0 0.00E+00 0.00E+00 - - - 1.035 0.9284 230117_WJC_METTL3_WT_vs_EV_F06.21946.21946.2 1.16 20-Jul R.VTWEPAPGEVK.G "sp|Q99715|COCA1_HUMAN,tr|D6RGG3|D6RGG3_HUMAN" 2 1211.6186 682.49 53997 21946 2 1211.616156 606.8166 Collagen alpha-1(XII) chain OS=Homo sapiens OX=9606 GN=COL12A1 PE=1 SV=2 4.53 3955.2 - 1.77E+07 - - - -2.0493 - 1.39 0.04 - 174 1 2 0 -0.0025 11 0 0 0 2.26E+08 3.31E+05 - - - 0.2265 1 230117_WJC_METTL3_WT_vs_EV_F06.21949.21949.2 1.36E-14 24/34 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 7.31 54000 21949 2 1911.9492 956.9806 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3955.4 - 2.97E+06 - - - 1.3729 - 4.475 0.617 - 2377.1 1 2 0 0.0026 18 0 0 0 4.00E+07 5.47E+06 - - - 7.2815 0.9681 230117_WJC_METTL3_WT_vs_EV_F06.21950.21950.2 0.00034 24-Nov K.TVTNAVVTVPAYF.N "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1380.7289 - 54001 21950 2 1380.730359 691.3717 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.18 3955.5 - 2.65E+06 - - - 1.0444 - 1.705 0.423 - 217.5 1 1 0 0.0014 13 0 0 0 - - - - - 3.5342 1 230117_WJC_METTL3_WT_vs_EV_F06.21955.21955.2 5.86E-08 15/28 K.YFLVGAGAIGC[160.03]ELLK.N sp|P22314|UBA1_HUMAN 1 1609.8538 -1 54006 21955 2 1609.856084 805.9342 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.99 3956 - 744932 - - - 1.4181 - 2.388 0.571 - 571.9 1 2 0 0.0023 15 0 0 0 0.00E+00 0.00E+00 - - - 5.3977 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21957.21957.3 5.11E-05 Aug-52 K.LLPVLVHTFWIDTK.N sp|Q13505|MTX1_HUMAN 1 1680.9603 1.79 54008 21957 3 1680.96332 561.3274 Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1 PE=1 SV=3 6.74 3956.3 - 722705 - - - 1.7883 - 1.89 0.447 - 68.8 1 2 0 0.003 14 0 0 0 1.71E+06 9.53E+05 - - - 5.2145 0.9562 230117_WJC_METTL3_WT_vs_EV_F06.21958.21958.2 3.78E-05 18-Oct K.DWVFLNYTYK[136.11].R "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN" 2 1355.6641 -1 54009 21958 2 1356.671348 678.8393 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.83 3956.4 - 640662 - - - 742.9635 - 1.961 0.473 - 392 1 2 0 1.0072 10 0 0 0 0.00E+00 0.00E+00 - - - 4.0981 1 230117_WJC_METTL3_WT_vs_EV_F06.21967.21967.2 1.33E-05 18-Dec K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 999 54017 21967 2 1146.629503 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3957.4 - 1.20E+07 - - - 0.8965 - 2.293 0.515 - 425.5 1 2 0 0.001 10 0 0 0 6.32E+07 0.00E+00 - - - 5.1609 0.8885 230117_WJC_METTL3_WT_vs_EV_F06.21973.21973.2 0.0364 18-Aug K.ANINVENAFF.T sp|P61006|RAB8A_HUMAN 1 1137.5455 - 54023 21973 2 1137.548433 569.78 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 4 3957.8 - 2.35E+06 - - - 2.6012 - 1.533 0.28 - 123.7 1 1 0 0.003 10 0 0 0 - - - - - 2.3007 1 230117_WJC_METTL3_WT_vs_EV_F06.21974.21974.2 3.83E-11 19/34 K.LGGSLADSYLDEGFLLDK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1919.9608 -1 54024 21974 2 1919.962044 960.9877 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3957.9 - 2.18E+06 - - - 0.661 - 3.723 0.671 - 1404.5 1 2 0 0.0013 18 0 0 0 0.00E+00 0.00E+00 - - - 7.2284 1 230117_WJC_METTL3_WT_vs_EV_F06.21976.21976.3 5.08E-07 19/72 R.LPVDYYGIPFAAPTALASR.D sp|Q5T6F2|UBAP2_HUMAN 1 2021.0622 -1 54026 21976 3 2021.062761 674.6947 Ubiquitin-associated protein 2 OS=Homo sapiens OX=9606 GN=UBAP2 PE=1 SV=1 5.83 3958.1 - 741170 - - - 0.2711 - 2.753 0.565 - 332.1 1 2 0 0.0005 19 0 0 0 0.00E+00 0.00E+00 - - - 7.327 0.9625 230117_WJC_METTL3_WT_vs_EV_F06.21977.21977.2 0.00392 16-Oct F.AAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 999.5601 2.66 54027 21977 2 999.560196 500.7873 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3958.2 - 710994 - - - 0.1351 - 2.067 0.355 - 431.5 1 1 0 0.0001 9 0 0 0 5.43E+06 2.04E+06 - - - 3.7636 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.21980.21980.2 3.47E-05 20-Dec K.VMVQPINLIFR.Y sp|P62304|RUXE_HUMAN 1 1328.7639 1.35 54028 21980 2 1328.764376 665.3892 Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1 9.72 3958.7 - 1.35E+07 - - - 0.3861 - 1.91 0.49 - 493.2 1 2 0 0.0005 11 0 0 0 6.63E+07 4.90E+07 - - - 4.4105 1 230117_WJC_METTL3_WT_vs_EV_F06.21987.21987.2 1.24E-06 18/28 K.AVLDSYEYFAVLAAK[136.11].E sp|P82664|RT10_HUMAN 1 1666.8698 -1 54035 21987 2 1666.867533 834.4422 "28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2" 4.37 3959.2 - 1.20E+06 - - - -1.345 - 3.33 0.655 - 898.6 1 2 0 -0.0022 15 0 0 0 0.00E+00 0.00E+00 - - - 6.8357 1 230117_WJC_METTL3_WT_vs_EV_F06.21988.21988.2 3.28E-10 15/28 K.AVLDSYEYFAVLAAK.E sp|P82664|RT10_HUMAN 1 1658.8556 1.45 54036 21988 2 1658.856304 830.4351 "28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2" 4.37 3959.4 - 1.18E+06 - - - 0.4395 - 3.033 0.665 - 596.8 1 2 0 0.0007 15 0 0 0 5.86E+06 4.03E+06 - - - 6.6803 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.21989.21989.3 1.14E-06 13/44 R.FFALPYVDHFLR[166.11].L sp|Q9HD33|RM47_HUMAN 1 1533.8008 0.71 54037 21989 3 1533.806438 512.2742 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 6.74 3959.5 - 1.06E+06 - - - 3.6817 - 2.421 0.56 - 157.4 1 2 0 0.0056 12 0 0 0 4.07E+06 5.77E+06 - - - 7.2327 1 230117_WJC_METTL3_WT_vs_EV_F06.21993.21993.2 0.000109 20-Nov R.IAFWDDVYGFK.M sp|O60678|ANM3_HUMAN 1 1359.6499 -1 54041 21993 2 1359.64774 680.8322 Protein arginine N-methyltransferase 3 OS=Homo sapiens OX=9606 GN=PRMT3 PE=1 SV=4 4.21 3960 - 919184 - - - -1.6173 - 2.417 0.514 - 398.9 1 2 0 -0.0022 11 0 0 0 0.00E+00 0.00E+00 - - - 5.2242 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.21995.21995.2 2.69E-05 26-Oct R.GVSVWPVGLVGGLR[166.11].F "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN" 2 1404.8117 0.82 54043 21995 2 1404.809576 703.4131 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 9.75 3960.3 - 836207 - - - -1.5048 - 1.998 0.462 - 156.3 1 2 0 -0.0021 14 0 0 0 6.12E+06 7.44E+06 - - - 4.1896 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.22005.22005.2 0.000126 20-Oct K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 999 54051 22005 2 1106.547894 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3961.3 - 4.56E+06 - - - 1.3483 - 2.141 0.415 - 234 1 2 0 0.0015 11 0 0 0 2.01E+07 0.00E+00 - - - 4.1651 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.22009.22009.2 0.0217 16-Sep R.C[160.03]LLAYFLDK.S "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1141.5842 2.33 54055 22009 2 1141.586568 571.7994 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 5.83 3961.6 - 1.46E+06 - - - 2.1023 - 1.903 0.417 - 279.7 1 2 0 0.0024 9 0 0 0 1.68E+07 7.20E+06 - - - 3.9817 1 230117_WJC_METTL3_WT_vs_EV_F06.22020.22020.2 4.42E-06 17/26 M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 1.2 54064 22020 2 1686.907743 844.4607 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3963 - 1.19E+07 - - - 0.5756 - 3.157 0.591 - 1060.4 1 2 0 0.001 14 0 0 0 6.30E+07 5.27E+07 - - - 6.2907 1 230117_WJC_METTL3_WT_vs_EV_F06.22022.22022.2 2.23E-07 15/26 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.2 54066 22022 2 1676.898591 839.4565 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3963.1 - 1.51E+07 - - - 0.0531 - 3.203 0.558 - 864.5 1 2 0 0.0001 14 0 0 0 6.30E+07 5.27E+07 - - - 6.0836 1 230117_WJC_METTL3_WT_vs_EV_F06.22024.22024.3 1.25E-08 14/52 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.34 54068 22024 3 1676.899767 559.9734 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3963.2 - 6.05E+06 - - - 0.7544 - 2.96 0.582 - 283.7 1 2 0 0.0013 14 0 0 0 1.88E+07 1.41E+07 - - - 7.9123 1 230117_WJC_METTL3_WT_vs_EV_F06.22026.22026.3 1.18E-07 13/52 M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 -1 54070 22026 3 1686.90933 563.3095 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3963.2 - 4.20E+06 - - - 1.5164 - 2.825 0.488 - 238 1 2 0 0.0026 14 0 0 0 0.00E+00 0.00E+00 - - - 6.7399 1 230117_WJC_METTL3_WT_vs_EV_F06.22027.22027.2 6.70E-09 22-Dec K.LIC[160.03]C[160.03]DILDVLDK.H "sp|P62258|1433E_HUMAN,tr|K7EIT4|K7EIT4_HUMAN" 2 1475.7364 1.55 54071 22027 2 1475.736565 738.8755 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 3.93 3963.3 - 4.16E+06 - - - 0.1199 - 2.517 0.646 - 399.2 1 2 0 0.0002 12 0 0 0 1.89E+07 1.22E+07 - - - 6.241 0.9412 230117_WJC_METTL3_WT_vs_EV_F06.22028.22028.2 0.641 20-Apr K.DLTNVQNLQK[136.11]K[136.11].H "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1315.7431 0.001 54072 22028 2 1315.742612 658.8788 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.59 3963.3 - 2.68E+06 - - - -0.3435 - 0.857 0.177 - 22.7 4 2 0 -0.0005 11 0 0 0 0.00E+00 1.31E+07 - - - -0.3382 1 230117_WJC_METTL3_WT_vs_EV_F06.22029.22029.2 6.63E-05 15/26 K.VPGLPTPIENMILR.Y "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1548.8698 2.16 54073 22029 2 1548.870203 775.4422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3963.4 - 2.58E+06 - - - 0.2699 - 2.303 0.517 - 503.1 1 2 0 0.0004 14 0 0 0 1.26E+07 5.86E+06 - - - 4.9528 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.22031.22031.2 8.74E-05 13/24 R.ALTLGALTLPLAR.L sp|Q9BSJ8|ESYT1_HUMAN 1 1308.8129 -1 54075 22031 2 1308.813838 655.4137 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 9.79 3963.5 - 2.06E+06 - - - 0.6999 - 2.624 0.356 - 644.8 1 2 0 0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 4.1461 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.22033.22033.2 0.00159 26-Nov K.VPGLPTPIENMILR[166.11].Y "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1558.8781 2.16 54077 22033 2 1558.878436 780.4463 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3963.6 - 1.84E+06 - - - 0.2444 - 1.975 0.423 - 225.8 1 2 0 0.0004 14 0 0 0 1.26E+07 5.86E+06 - - - 3.873 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.22036.22036.2 0.000517 16-Oct K.AGLVELLLR.E "sp|Q13425|SNTB2_HUMAN,tr|A0A140TA73|A0A140TA73_HUMAN" 2 982.6175 2.16 54080 22036 2 982.61725 492.316 Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1 6.05 3963.8 - 1.63E+06 - - - -0.2707 - 2.172 0.295 - 297.1 1 2 0 -0.0003 9 0 0 0 7.66E+06 3.55E+06 - - - 3.4638 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.22038.22038.2 4.81E-05 14-Nov R.C[160.03]FLSWLVK.L sp|Q92900|RENT1_HUMAN 1 1051.5525 -1 54082 22038 2 1051.552873 526.7835 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.22 3964 - 905320 - - - 0.3794 - 1.914 0.467 - 490.8 1 2 0 0.0004 8 0 0 0 0.00E+00 0.00E+00 - - - 4.4481 0.999 230117_WJC_METTL3_WT_vs_EV_F06.22039.22039.2 0.00814 26-Nov R.VGVDPLIIPTDYWK.K "sp|Q9NQW7|XPP1_HUMAN,tr|Q5T6H2|Q5T6H2_HUMAN,tr|Q5T6H3|Q5T6H3_HUMAN,tr|Q5T6H7|Q5T6H7_HUMAN" 4 1614.8657 -1 54083 22039 2 1614.867406 808.4401 Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3 4.21 3964.2 - 886845 - - - 1.0286 - 1.61 0.297 - 151.4 1 2 0 0.0017 14 0 0 0 0.00E+00 0.00E+00 - - - 2.4292 0.9975 230117_WJC_METTL3_WT_vs_EV_F06.22041.22041.2 0.741 20-Aug R.LDNTLEEIIFK.L sp|Q86SE9|PCGF5_HUMAN 1 1333.7129 2.29 54084 22041 2 1333.711262 667.8637 Polycomb group RING finger protein 5 OS=Homo sapiens OX=9606 GN=PCGF5 PE=1 SV=1 4.14 3964.4 - 865441 - - - -1.2529 - 1.743 0.285 - 158.6 1 2 0 -0.0017 11 0 0 0 3.62E+06 1.58E+06 - - - 2.6485 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.22043.22043.2 0.0249 16-Aug R.FLILPDMLK.N sp|P62318|SMD3_HUMAN 1 1088.6304 1.52 54086 22043 2 1088.631162 545.3225 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.84 3964.5 - 1.76E+07 - - - 0.7101 - 1.589 0.422 - 201.1 1 2 0 0.0008 9 0 0 0 4.32E+07 2.84E+07 - - - 3.4974 1 230117_WJC_METTL3_WT_vs_EV_F06.22046.22046.2 0.000992 22-Dec R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 999 54089 22046 2 1328.718462 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3964.6 - 8.39E+06 - - - -0.2145 - 2.267 0.507 - 373.7 1 2 0 -0.0003 12 0 0 0 1.47E+07 0.00E+00 - - - 4.9391 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.22049.22049.2 0.000258 20-Aug K.LVPDLLAIVQR.K "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1235.7602 1.24 54092 22049 2 1235.761062 618.8874 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.84 3964.8 - 2.23E+06 - - - 0.7315 - 1.859 0.43 - 247.5 1 2 0 0.0009 11 0 0 0 5.92E+06 4.78E+06 - - - 3.894 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.22055.22055.2 0.00886 20-Nov K.VNLLSVLEAAK[136.11].M sp|Q9BRX8|PXL2A_HUMAN 1 1163.7005 -1 54098 22055 2 1163.700934 582.8575 Peroxiredoxin-like 2A OS=Homo sapiens OX=9606 GN=PRXL2A PE=1 SV=3 5.97 3965.4 - 1.22E+06 - - - 0.3523 - 1.895 0.332 - 326.9 1 2 0 0.0004 11 0 0 0 0.00E+00 0.00E+00 - - - 3.2223 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.22057.22057.2 6.81E-05 13/20 R.AIQDAILEVLK.E "sp|Q86Y56|DAAF5_HUMAN,tr|H0Y650|H0Y650_HUMAN,tr|E9PGY2|E9PGY2_HUMAN" 3 1211.7125 -1 54100 22057 2 1211.711041 606.8635 Dynein axonemal assembly factor 5 OS=Homo sapiens OX=9606 GN=DNAAF5 PE=1 SV=4 4.37 3965.7 - 1.07E+06 - - - -1.2363 - 2.131 0.416 - 273 1 2 0 -0.0015 11 0 0 0 0.00E+00 0.00E+00 - - - 4.1599 0.9967 230117_WJC_METTL3_WT_vs_EV_F06.22059.22059.3 6.03E-05 14/48 R.DPQLVPILIEAAR.N "sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 2 1433.8242 -1 54102 22059 3 1433.833981 478.9487 "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=NSDHL PE=1 SV=2" 4.37 3965.9 - 939982 - - - 6.8112 - 2.2 0.383 - 258.8 1 2 0 0.0098 13 0 0 0 0.00E+00 0.00E+00 - - - 4.9451 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22063.22063.3 0.0452 14/44 K.C[160.03]LVFSLIGLHFK[136.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1440.8043 -1 54105 22063 3 1440.805792 481.2754 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3966.3 - 1.78E+06 - - - 1.0508 - 2.251 0.384 - 276.8 1 2 0 0.0015 12 0 0 0 0.00E+00 0.00E+00 - - - 5.0698 1 230117_WJC_METTL3_WT_vs_EV_F06.22065.22065.2 6.17E-05 14/22 R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 -1 54107 22065 2 1301.708811 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3966.4 - 4.70E+06 - - - 0.7398 - 2.717 0.555 - 453.8 1 2 0 0.001 12 0 0 0 0.00E+00 0.00E+00 - - - 5.7699 1 230117_WJC_METTL3_WT_vs_EV_F06.22067.22067.2 0.000366 20-Oct K.LVLADLLEPVK.T sp|Q9BVJ6|UT14A_HUMAN 1 1208.738 1.56 54109 22067 2 1208.743066 605.3763 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3966.5 - 1.71E+06 - - - 4.1696 - 2.178 0.493 - 261.8 1 2 0 0.005 11 0 0 0 1.53E+07 9.81E+06 - - - 4.7865 0.9944 230117_WJC_METTL3_WT_vs_EV_F06.22069.22069.2 0.384 12-Jun K.DVLDSVL.- sp|P81605|DCD_HUMAN 1 759.4014 - 54111 22069 2 759.401415 380.708 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.56 3966.7 - 1.62E+06 - - - -0.0263 - 1.243 0.199 - 136.3 1 2 0 0 7 0 0 0 - - - - - 1.2001 1 230117_WJC_METTL3_WT_vs_EV_F06.22070.22070.2 4.10E-06 18-Nov K.GGFDWNLVFK.W sp|Q10471|GALT2_HUMAN 1 1181.5869 -1 54112 22070 2 1181.588419 591.8007 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.84 3966.8 - 1.52E+06 - - - 1.2475 - 1.954 0.563 - 279.8 1 2 0 0.0015 10 0 0 0 0.00E+00 0.00E+00 - - - 5.0687 1 230117_WJC_METTL3_WT_vs_EV_F06.22071.22071.3 2.38E-06 18/68 K.LLGTIYTAAEEIEAVGGK.A sp|Q6YN16|HSDL2_HUMAN 1 1833.9724 -1 54113 22071 3 1833.974277 612.3314 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3966.8 - 1.30E+06 - - - 1.0262 - 3.097 0.512 - 453.5 1 2 0 0.0019 18 0 0 0 0.00E+00 0.00E+00 - - - 7.0627 1 230117_WJC_METTL3_WT_vs_EV_F06.22072.22072.2 0.00156 13/24 R.DPQLVPILIEAAR.N "sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 2 1433.8242 -1 54114 22072 2 1433.828634 717.9194 "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=NSDHL PE=1 SV=2" 4.37 3966.9 - 1.18E+06 - - - 3.082 - 2.465 0.501 - 423.9 1 2 0 0.0044 13 0 0 0 0.00E+00 0.00E+00 - - - 5.0555 1 230117_WJC_METTL3_WT_vs_EV_F06.22074.22074.2 8.27E-11 18/34 K.LLGTIYTAAEEIEAVGGK.A sp|Q6YN16|HSDL2_HUMAN 1 1833.9724 -1 54116 22074 2 1833.972645 917.9935 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3967.2 - 828939 - - - 0.1363 - 3.762 0.646 - 1101.4 1 2 0 0.0003 18 0 0 0 0.00E+00 0.00E+00 - - - 7.0697 1 230117_WJC_METTL3_WT_vs_EV_F06.22075.22075.2 8.37E-07 15/22 K.QFEELTLGEFLK.L "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1452.75 -1 54117 22075 2 1452.748871 727.3823 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.25 3967.3 - 794763 - - - -0.8095 - 2.773 0.514 - 1038.1 1 2 0 -0.0012 12 0 0 0 0.00E+00 0.00E+00 - - - 5.5206 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.22076.22076.2 9.50E-05 20-Dec K.LVLADLLEPVK[136.11].T sp|Q9BVJ6|UT14A_HUMAN 1 1216.7522 1.55 54118 22076 2 1216.753867 609.3834 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3967.4 - 588943 - - - 1.3487 - 2.022 0.379 - 356.3 1 2 0 0.0016 11 0 0 0 1.53E+07 9.88E+06 - - - 3.7445 0.998 230117_WJC_METTL3_WT_vs_EV_F06.22079.22079.3 0.0455 13/56 K.NLAEALLTYETLDAK.E sp|Q96TA2|YMEL1_HUMAN 1 1663.8669 1.66 54121 22079 3 1663.865694 555.6296 ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX=9606 GN=YME1L1 PE=1 SV=2 4.14 3967.8 - 504261 - - - -0.7056 - 2.312 0.224 - 225.7 1 2 0 -0.0012 15 0 0 0 1.52E+06 9.18E+05 - - - 3.224 1 230117_WJC_METTL3_WT_vs_EV_F06.22083.22083.2 1.37E-13 17/34 K.LLGTIYTAAEEIEAVGGK[136.11].A sp|Q6YN16|HSDL2_HUMAN 1 1841.9866 -1 54124 22083 2 1841.986081 922.0006 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3968.3 - 225214 - - - -0.279 - 3.658 0.679 - 1064.9 1 2 0 -0.0005 18 0 0 0 0.00E+00 0.00E+00 - - - 7.2445 1 230117_WJC_METTL3_WT_vs_EV_F06.22090.22090.2 0.000102 14/24 K.IPLKPPPLELLNV.- sp|O15504|NUP42_HUMAN 1 1441.8908 1.81 54131 22090 2 1441.892645 721.9527 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 3968.9 - 1.18E+06 - - - 1.2532 - 2.386 0.505 - 690.9 1 2 0 0.0018 13 0 0 0 4.84E+06 2.67E+06 - - - 5.0023 1 230117_WJC_METTL3_WT_vs_EV_F06.22091.22091.2 0.00463 18-Nov K.STLLLLLTGK[136.11].L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1065.6889 -1 54132 22091 2 1065.69005 533.8517 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3969.1 - 1.13E+06 - - - 1.0819 - 2.303 0.447 - 458.4 1 2 0 0.0012 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6707 0.9998 230117_WJC_METTL3_WT_vs_EV_F06.22097.22097.3 0.000255 Oct-44 K.C[160.03]LVFSLIGLHFK.L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1432.7901 -1 54138 22097 3 1432.790756 478.604 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3969.7 - 755306 - - - 0.4732 - 1.95 0.414 - 173.6 1 2 0 0.0007 12 0 0 0 0.00E+00 0.00E+00 - - - 5.0066 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.22098.22098.2 0.0166 24-Dec K.IPLK[136.11]PPPLELLNV.- sp|O15504|NUP42_HUMAN 1 1449.905 1.81 54139 22098 2 1449.905346 725.9598 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 3969.8 - 740702 - - - 0.2124 - 2.127 0.455 - 480 1 2 0 0.0003 13 0 0 0 4.84E+06 2.67E+06 - - - 4.3385 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.22100.22100.2 0.00116 28-Oct K.VNALLPTETFIPVIR.G "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1681.9767 -1 54141 22100 2 1681.980322 841.9956 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.97 3970.1 - 525053 - - - 2.1576 - 2.022 0.412 - 251.1 1 2 0 0.0036 15 0 0 0 0.00E+00 0.00E+00 - - - 3.8139 0.9965 230117_WJC_METTL3_WT_vs_EV_F06.22106.22106.2 0.0593 14-Jul R.GFGFILFK[136.11].D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 935.536 0.8 54146 22106 2 935.536659 468.7753 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3970.7 - 6.48E+06 - - - 0.6777 - 1.358 0.184 - 142.8 1 2 0 0.0006 8 0 0 0 3.27E+07 4.07E+07 - - - 1.3227 1 230117_WJC_METTL3_WT_vs_EV_F06.22107.22107.2 3.51E-05 18-Nov K.STLLLLLTGK.L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1057.6747 -1 54147 22107 2 1057.677323 529.8446 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3970.8 - 4.19E+06 - - - 2.4828 - 2.226 0.557 - 436.6 1 2 0 0.0026 10 0 0 0 0.00E+00 0.00E+00 - - - 5.3878 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.22109.22109.2 0.0233 14-Jul R.GFGFILFK.D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 927.5218 0.8 54149 22109 2 927.523703 464.7682 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3970.9 - 3.12E+06 - - - 2.0248 - 1.384 0.214 - 145.2 1 2 0 0.0019 8 0 0 0 3.27E+07 4.07E+07 - - - 1.6011 0.9972 230117_WJC_METTL3_WT_vs_EV_F06.22110.22110.2 0.302 14-Aug K.GSLLDFLK.E "sp|P07947|YES_HUMAN,sp|P09769|FGR_HUMAN,sp|P07948|LYN_HUMAN,sp|P08631|HCK_HUMAN,sp|P06241|FYN_HUMAN,sp|P12931|SRC_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|J3QRU1|J3QRU1_HUMAN" 9 891.5066 -1 54150 22110 2 891.507979 446.7606 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 3970.9 - 2.66E+06 - - - 1.5816 - 1.503 0.157 - 216.5 1 2 0 0.0014 8 0 0 0 0.00E+00 0.00E+00 - - - 1.429 1 230117_WJC_METTL3_WT_vs_EV_F06.22111.22111.2 2.09E-05 16-Oct R.VNILFDFVK.K sp|P55010|IF5_HUMAN 1 1093.6172 -1 54151 22111 2 1093.621806 547.8159 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.81 3971 - 1.84E+06 - - - 4.2282 - 2.047 0.514 - 379.2 1 2 0 0.0046 9 0 0 0 0.00E+00 0.00E+00 - - - 4.9085 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.22112.22112.2 0.155 16-Aug R.VNILFDFVK[136.11].K sp|P55010|IF5_HUMAN 1 1101.6314 -1 54152 22112 2 1101.632683 551.823 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.81 3971.1 - 1.82E+06 - - - 1.181 - 1.53 0.227 - 179.2 1 2 0 0.0013 9 0 0 0 0.00E+00 0.00E+00 - - - 1.9475 1 230117_WJC_METTL3_WT_vs_EV_F06.22113.22113.2 2.19E-05 18-Dec K.ILYDILAFAK.E "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1165.6747 -1 54153 22113 2 1165.678121 583.8446 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.83 3971.2 - 1.27E+06 - - - 2.9374 - 2.267 0.516 - 349.7 1 2 0 0.0034 10 0 0 0 0.00E+00 0.00E+00 - - - 5.1357 1 230117_WJC_METTL3_WT_vs_EV_F06.22114.22114.2 1.94E-05 18-Dec K.ILYDILAFAK[136.11].E "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1173.6889 -1 54154 22114 2 1173.69281 587.8517 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.83 3971.3 - 1.16E+06 - - - 3.3339 - 2.467 0.474 - 337.3 1 2 0 0.0039 10 0 0 0 0.00E+00 0.00E+00 - - - 5.0613 1 230117_WJC_METTL3_WT_vs_EV_F06.22116.22116.2 7.12E-06 20-Nov R.LWGLTEMFPER.V sp|Q9NS69|TOM22_HUMAN 1 1377.6751 1.28 54156 22116 2 1377.67695 689.8448 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 4.53 3971.5 - 1.01E+06 - - - 1.337 - 2.237 0.54 - 442.8 1 2 0 0.0018 11 0 0 0 6.01E+06 4.69E+06 - - - 5.2069 1 230117_WJC_METTL3_WT_vs_EV_F06.22117.22117.2 0.000491 13/24 R.LLSLISIALPENK.V "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1409.8494 3.19 54157 22117 2 1409.852379 705.932 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 6 3971.6 - 941194 - - - 2.1364 - 2.697 0.523 - 499.8 1 2 0 0.003 13 0 0 0 4.00E+06 1.25E+06 - - - 5.4493 0.996 230117_WJC_METTL3_WT_vs_EV_F06.22118.22118.2 0.156 14-Jul K.GSLLDFLK[136.11].E "sp|P07947|YES_HUMAN,sp|P09769|FGR_HUMAN,sp|P07948|LYN_HUMAN,sp|P08631|HCK_HUMAN,sp|P06241|FYN_HUMAN,sp|P12931|SRC_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|J3QRU1|J3QRU1_HUMAN" 9 899.5208 -1 54158 22118 2 899.522544 450.7677 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 3971.7 - 854206 - - - 1.9733 - 1.383 0.163 - 139.8 1 2 0 0.0018 8 0 0 0 0.00E+00 0.00E+00 - - - 1.2223 0.9963 230117_WJC_METTL3_WT_vs_EV_F06.22119.22119.2 3.7 16-Sep K.EVIASIISR[166.11].Y "sp|Q99551|MTEF1_HUMAN,tr|C9JNM8|C9JNM8_HUMAN,tr|B4DPR9|B4DPR9_HUMAN,tr|C9JE25|C9JE25_HUMAN" 4 996.5843 0.001 54159 22119 2 996.58712 499.2994 "Transcription termination factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=MTERF1 PE=1 SV=1" 6.1 3971.8 - 813150 - - - 2.8136 - 1.738 0.15 - 165.5 2 2 0 0.0028 9 0 0 0 0.00E+00 3.56E+06 - - - 1.6126 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.22121.22121.2 0.000509 26-Sep R.EAGLAPVPMIIFAK.D "sp|P06132|DCUP_HUMAN,tr|A0A1B0GVN9|A0A1B0GVN9_HUMAN,tr|H0Y5R6|H0Y5R6_HUMAN,tr|A0A494C0S8|A0A494C0S8_HUMAN,tr|A0A494C0Q8|A0A494C0Q8_HUMAN,tr|A0A494C085|A0A494C085_HUMAN" 6 1455.816 -1 54161 22121 2 1455.820158 728.9153 Uroporphyrinogen decarboxylase OS=Homo sapiens OX=9606 GN=UROD PE=1 SV=2 6.1 3972.1 - 667802 - - - 2.885 - 1.931 0.353 - 219.2 1 2 0 0.0042 14 0 0 0 0.00E+00 0.00E+00 - - - 3.2983 0.9992 230117_WJC_METTL3_WT_vs_EV_F06.22122.22122.3 0.0156 Sep-56 R.AVPVWDVLASGYVSR.A "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 8 1617.8515 -1 54162 22122 3 1617.854759 540.2911 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.88 3972.2 - 450307 - - - 2.0193 - 1.82 0.298 - 88.7 1 2 0 0.0033 15 0 0 0 0.00E+00 0.00E+00 - - - 3.4241 1 230117_WJC_METTL3_WT_vs_EV_F06.22132.22132.2 0.000578 13/26 K.IFFIDPNERPVTLY.H "sp|O95619|YETS4_HUMAN,tr|F8W1B9|F8W1B9_HUMAN,tr|F8VTR4|F8VTR4_HUMAN" 3 1722.8981 -1 54171 22132 2 1722.902933 862.4563 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 4.37 3973.3 - 668064 - - - 2.8005 - 2.286 0.488 - 350.6 1 1 0 0.0048 14 0 0 0 0.00E+00 0.00E+00 - - - 4.7187 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.22135.22135.2 0.0148 16-Jul K.EVWDYVFFK[136.11].E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PRP1|A0A6I8PRP1_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 1239.6056 -1 54174 22135 2 1239.606078 620.8101 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.37 3973.7 - 528664 - - - 0.4171 - 1.66 0.392 - 170.1 1 2 0 0.0005 9 0 0 0 0.00E+00 0.00E+00 - - - 3.4024 1 230117_WJC_METTL3_WT_vs_EV_F06.22136.22136.2 1.63E-05 14/24 R.VSELQVLLGYAGR.N "sp|O75925|PIAS1_HUMAN,tr|H3BSI8|H3BSI8_HUMAN" 2 1403.7773 -1 54175 22136 2 1403.779042 702.8959 E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=9606 GN=PIAS1 PE=1 SV=2 5.97 3973.8 - 471288 - - - 1.2659 - 2.519 0.514 - 690.1 1 2 0 0.0018 13 0 0 0 0.00E+00 0.00E+00 - - - 5.208 1 230117_WJC_METTL3_WT_vs_EV_F06.22152.22152.2 2.81E-06 22-Dec K.LIQLMEEIMAEK.E "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1446.7462 1.47 54189 22152 2 1446.746378 724.3804 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.25 3975.6 - 2.37E+06 - - - 0.1064 - 2.469 0.595 - 518.1 1 2 0 0.0002 12 0 0 0 8.20E+06 5.58E+06 - - - 5.8137 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22153.22153.3 0.011 14/44 R.EGGFLLLHTLLR.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1367.7925 -1 54190 22153 3 1367.79228 456.9381 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.85 3975.7 - 1.88E+06 - - - -0.1762 - 2.43 0.399 - 261.4 1 2 0 -0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4495 0.998 230117_WJC_METTL3_WT_vs_EV_F06.22156.22156.2 3.69E-05 13/22 K.IIDEDGLLNLIR[166.11].T "sp|P35251|RFC1_HUMAN,tr|H0Y8U4|H0Y8U4_HUMAN" 2 1392.7852 -1 54193 22156 2 1392.781934 697.3999 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 4.03 3976 - 1.48E+06 - - - -2.3449 - 2.149 0.406 - 405.8 1 2 0 -0.0033 12 0 0 0 0.00E+00 0.00E+00 - - - 4.0515 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.22160.22160.3 0.0525 Dec-44 R.EGGFLLLHTLLR[166.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1377.8008 1 54197 22160 3 1377.800151 460.2742 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.85 3976.4 - 1.15E+06 - - - -0.4645 - 2.301 0.31 - 179.1 1 2 0 -0.0006 12 0 0 0 2.46E+06 2.47E+06 - - - 4.3059 0.999 230117_WJC_METTL3_WT_vs_EV_F06.22162.22162.2 6.99E-05 18-Sep R.DFVVGALILR[166.11].S sp|Q9NUD5|ZCHC3_HUMAN 1 1111.6629 1.17 54199 22162 2 1111.661302 556.8387 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 5.84 3976.7 - 934909 - - - -1.4375 - 1.744 0.517 - 246.6 1 2 0 -0.0016 10 0 0 0 4.70E+06 4.00E+06 - - - 4.4115 1 230117_WJC_METTL3_WT_vs_EV_F06.22163.22163.2 0.000485 26-Nov R.GLLEESSFATLFPK[136.11].Y sp|Q13601|KRR1_HUMAN 1 1545.817 0.95 54200 22163 2 1545.810631 773.9158 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3976.8 - 790909 - - - -4.1273 - 2.582 0.535 - 282.8 1 2 0 -0.0064 14 0 0 0 7.34E+06 7.69E+06 - - - 5.3709 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.22164.22164.2 1.25 13/18 R.ILGLLDAYLK[136.11].T sp|P26641|EF1G_HUMAN 1 1125.6889 0.87 54201 22164 2 1125.692225 563.8517 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3977 - 619690 - - - 2.9564 - 2.41 0.324 - 375.8 1 2 0 0.0033 10 0 0 0 4.36E+07 5.03E+07 - - - 3.8883 1 230117_WJC_METTL3_WT_vs_EV_F06.22169.22169.2 2.21E-08 18/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 5.59 54205 22169 2 1591.943688 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3977.6 - 2.81E+06 - - - -0.8235 - 3.123 0.615 - 758 1 2 0 -0.0013 15 0 0 0 3.50E+07 6.25E+06 - - - 6.3828 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22170.22170.3 0.000716 Nov-56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 6.34 54206 22170 3 1591.946964 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3977.6 - 1.74E+06 - - - 1.2343 - 2.12 0.446 - 135.1 1 2 0 0.002 15 0 0 0 1.58E+07 2.49E+06 - - - 5.4726 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.22172.22172.2 0.0308 18-Oct R.ILGLLDAYLK.T sp|P26641|EF1G_HUMAN 1 1117.6747 0.87 54208 22172 2 1117.677172 559.8446 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3977.7 - 1.24E+07 - - - 2.2144 - 2.236 0.296 - 228.7 1 2 0 0.0025 10 0 0 0 4.36E+07 5.03E+07 - - - 3.4726 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.22173.22173.2 0.000958 18-Oct K.NIFAILQSVK.A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1131.6652 -1 54209 22173 2 1131.66719 566.8399 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3977.7 - 1.20E+07 - - - 1.7629 - 1.964 0.338 - 226.1 1 2 0 0.002 10 0 0 0 0.00E+00 0.00E+00 - - - 3.4209 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.22175.22175.2 1.2 18-Oct K.NIFAILQSVK[136.11].A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1139.6794 -1 54211 22175 2 1139.681563 570.847 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3977.8 - 7.04E+06 - - - 1.9023 - 2.033 0.327 - 229 1 2 0 0.0022 10 0 0 0 0.00E+00 0.00E+00 - - - 3.436 0.9964 230117_WJC_METTL3_WT_vs_EV_F06.22180.22180.2 0.0151 20-Oct K.TFSFAIPLIER.L sp|Q9BQ39|DDX50_HUMAN 1 1292.7129 -1 54216 22180 2 1292.718732 647.3637 ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1 5.66 3978.2 - 1.40E+06 - - - 4.5323 - 1.699 0.31 - 322.2 1 2 0 0.0059 11 0 0 0 0.00E+00 0.00E+00 - - - 2.7627 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.22183.22183.2 0.00062 13/22 K.ILDLSNFEILAK.V "sp|Q9NR09|BIRC6_HUMAN,tr|A0A3B3IUB9|A0A3B3IUB9_HUMAN" 2 1374.7759 -1 54219 22183 2 1374.778404 688.3952 Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=BIRC6 PE=1 SV=2 4.37 3978.5 - 979693 - - - 1.8447 - 2.054 0.416 - 499.2 1 2 0 0.0025 12 0 0 0 0.00E+00 0.00E+00 - - - 4.0067 1 230117_WJC_METTL3_WT_vs_EV_F06.22185.22185.3 2.00E-06 18/44 K.LR[166.11]EC[160.03]LPLIIFLR[166.11].N sp|P62701|RS4X_HUMAN 1 1561.9281 0.89 54221 22185 3 1561.932017 521.65 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3978.8 - 816692 - - - 2.4886 - 3.277 0.551 - 667.7 1 2 1 0.0039 12 0 0 0 2.86E+07 3.21E+07 - - - 7.972 0.9974 230117_WJC_METTL3_WT_vs_EV_F06.22191.22191.3 2.84E-08 17/44 K.LREC[160.03]LPLIIFLR.N sp|P62701|RS4X_HUMAN 1 1541.9116 0.89 54226 22191 3 1541.913101 514.9778 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3979.6 - 4.18E+06 - - - 0.98 - 3.231 0.478 - 640 1 2 1 0.0015 12 0 0 0 2.86E+07 3.21E+07 - - - 7.1196 1 230117_WJC_METTL3_WT_vs_EV_F06.22193.22193.2 3.14E-05 15/22 R.LGPLLDILADSR.H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1281.7293 1.59 54228 22193 2 1281.731522 641.8719 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3979.7 - 3.02E+06 - - - 1.771 - 2.681 0.483 - 852.8 1 2 0 0.0023 12 0 0 0 2.82E+07 1.77E+07 - - - 5.2026 1 230117_WJC_METTL3_WT_vs_EV_F06.22194.22194.3 5.30E-10 25/80 N.WITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 2344.2539 6.62 54229 22194 3 2344.257902 782.4253 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3979.8 - 2.73E+06 - - - 1.6944 - 3.829 0.641 - 562.9 1 1 0 0.004 21 0 0 0 1.12E+07 1.69E+06 - - - 8.9042 0.9577 230117_WJC_METTL3_WT_vs_EV_F06.22195.22195.2 0.00823 14-Aug K.KEDLVFIF.W "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 1009.5484 -1 54230 22195 2 1009.550244 505.7815 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.37 3979.8 - 2.34E+06 - - - 1.7929 - 1.575 0.37 - 192.2 1 1 0 0.0018 8 0 0 0 0.00E+00 0.00E+00 - - - 3.1433 1 230117_WJC_METTL3_WT_vs_EV_F06.22196.22196.3 1.49E-07 18/56 R.TVFRPPLDIYDVLIR.L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0C4DFX0|A0A0C4DFX0_HUMAN" 2 1816.0247 0.83 54231 22196 3 1816.028505 606.3488 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.63 3979.9 - 1.73E+06 - - - 2.0919 - 2.918 0.59 - 360.7 1 2 0 0.0038 15 0 0 0 4.88E+06 5.91E+06 - - - 7.9112 0.9688 230117_WJC_METTL3_WT_vs_EV_F06.22198.22198.2 0.00271 14-Aug R.EC[160.03]LNLWGY.E sp|Q86U44|MTA70_HUMAN 1 1053.459 - 54233 22198 2 1053.46071 527.7368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3980.1 - 1.28E+06 - - - 1.6545 - 1.652 0.41 - 250.1 1 1 0 0.0017 8 0 0 0 - - - - - 3.5827 1 230117_WJC_METTL3_WT_vs_EV_F06.22199.22199.3 1.20E-07 16/56 R.TVFR[166.11]PPLDIYDVLIR[166.11].L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0C4DFX0|A0A0C4DFX0_HUMAN" 2 1836.0412 1.37 54234 22199 3 1836.04402 613.021 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.63 3980.2 - 1.20E+06 - - - 1.5109 - 2.648 0.54 - 265.7 1 2 0 0.0028 15 0 0 0 9.10E+06 6.63E+06 - - - 7.1007 1 230117_WJC_METTL3_WT_vs_EV_F06.22200.22200.2 8.47E-11 22/30 K.LPIVNEDDELVAIIAR.T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1778.9778 -1 54235 22200 2 1778.981146 890.4962 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3980.3 - 886883 - - - 1.8724 - 4.047 0.657 - 1499.1 1 2 0 0.0033 16 0 0 0 0.00E+00 0.00E+00 - - - 7.3295 1 230117_WJC_METTL3_WT_vs_EV_F06.22201.22201.2 1.30E-06 14/26 K.LLSDFLDSEVSELR.T sp|Q9BPX3|CND3_HUMAN 1 1621.8199 -1 54236 22201 2 1621.822622 811.9172 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 3.92 3980.5 - 882950 - - - 1.6679 - 2.796 0.548 - 677.5 1 2 0 0.0027 14 0 0 0 0.00E+00 0.00E+00 - - - 5.6679 1 230117_WJC_METTL3_WT_vs_EV_F06.22202.22202.2 1.53E-05 14/24 R.SDFFLEGPFMPPR.M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1538.7228 2.39 54237 22202 2 1538.723623 770.3687 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3980.6 - 781530 - - - 0.544 - 2.646 0.541 - 663.5 1 2 0 0.0008 13 0 0 0 1.01E+07 4.22E+06 - - - 5.5339 1 230117_WJC_METTL3_WT_vs_EV_F06.22204.22204.2 5.07E-07 13/26 K.LLSDFLDSEVSELR[166.11].T sp|Q9BPX3|CND3_HUMAN 1 1631.8282 -1 54239 22204 2 1631.829672 816.9214 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 3.92 3980.8 - 685877 - - - 0.91 - 2.652 0.566 - 508.9 1 2 0 0.0015 14 0 0 0 0.00E+00 0.00E+00 - - - 5.6685 1 230117_WJC_METTL3_WT_vs_EV_F06.22205.22205.2 9.19E-05 22-Nov K.VNFLPEIITLSK[136.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1380.8108 1.18 54240 22205 2 1380.815329 691.4127 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.97 3980.9 - 654395 - - - 3.2778 - 2.099 0.525 - 313.2 1 2 0 0.0045 12 0 0 0 6.78E+06 5.72E+06 - - - 4.8681 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22206.22206.3 6.60E-06 16/60 K.LPIVNEDDELVAIIAR[166.11].T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1788.9861 -1 54241 22206 3 1788.986683 597.336 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3981.1 - 624953 - - - 0.3343 - 3.032 0.412 - 312.2 1 2 0 0.0006 16 0 0 0 0.00E+00 0.00E+00 - - - 5.9793 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.22208.22208.2 0.0322 20-Oct R.IDVYGFSALWK.F sp|Q9UBV8|PEF1_HUMAN 1 1297.6707 -1 54243 22208 2 1297.672327 649.8426 Peflin OS=Homo sapiens OX=9606 GN=PEF1 PE=1 SV=1 5.83 3981.3 - 518005 - - - 1.2738 - 1.835 0.325 - 258.9 1 2 0 0.0017 11 0 0 0 0.00E+00 0.00E+00 - - - 3.0831 1 230117_WJC_METTL3_WT_vs_EV_F06.22209.22209.2 1.39E-08 19/30 K.LPIVNEDDELVAIIAR[166.11].T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1788.9861 1.81 54244 22209 2 1788.988452 895.5003 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3981.4 - 494277 - - - 1.3231 - 3.833 0.666 - 981.5 1 2 0 0.0024 16 0 0 0 6.32E+06 3.50E+06 - - - 7.2628 1 230117_WJC_METTL3_WT_vs_EV_F06.22211.22211.3 1.91E-05 14/60 K.LPIVNEDDELVAIIAR.T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1778.9778 1.65 54245 22211 3 1778.97973 593.9999 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3981.6 - 3.42E+06 - - - 1.0765 - 2.655 0.55 - 254.9 1 2 0 0.0019 16 0 0 0 6.20E+06 3.76E+06 - - - 7.1768 1 230117_WJC_METTL3_WT_vs_EV_F06.22212.22212.2 2.67E-05 22-Dec K.VNFLPEIITLSK.E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1372.7966 -1 54246 22212 2 1372.805945 687.4056 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.97 3981.7 - 3.11E+06 - - - 6.8051 - 2.166 0.552 - 388.4 1 2 0 0.0093 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1487 1 230117_WJC_METTL3_WT_vs_EV_F06.22213.22213.2 0.42 14/22 R.LGPLLDILADSR[166.11].H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1291.7375 1.59 54247 22213 2 1291.739594 646.876 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3981.8 - 4.99E+06 - - - 1.604 - 2.804 0.402 - 678 1 2 0 0.0021 12 0 0 0 2.82E+07 1.77E+07 - - - 4.7224 1 230117_WJC_METTL3_WT_vs_EV_F06.22214.22214.2 1.26E-08 13/24 R.GNSIIMLEALERV.- "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1443.7756 -1 54248 22214 2 1443.777417 722.8951 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3981.8 - 1.98E+06 - - - 1.2931 - 2.766 0.604 - 748.2 1 2 0 0.0019 13 0 0 0 0.00E+00 0.00E+00 - - - 6.1128 1 230117_WJC_METTL3_WT_vs_EV_F06.22217.22217.2 1.72E-06 15/28 R.NFLVFQGAVESIAMK.N "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1652.8596 -1 54251 22217 2 1652.863065 827.4371 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 6 3982.1 - 1.30E+06 - - - 2.0879 - 3.01 0.611 - 616.8 1 2 0 0.0035 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2619 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.22218.22218.2 0.0294 14/22 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 1.01 54252 22218 2 1344.864394 673.4385 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3982.2 - 1.25E+06 - - - 1.4492 - 2.442 0.341 - 698.7 1 2 0 0.0019 12 0 0 0 1.68E+08 1.66E+08 - - - 3.9082 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.22219.22219.2 0.093 18-Aug K.GGPGLPLPPL.- sp|Q9H7N4|SFR19_HUMAN 1 916.5382 - 54253 22219 2 916.539068 459.2764 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.52 3982.3 - 1.20E+06 - - - 0.9438 - 1.473 0.293 - 201.7 1 2 0 0.0009 10 0 0 0 - - - - - 2.2859 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.22220.22220.2 0.183 13/22 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 1.01 54254 22220 2 1336.849064 669.4314 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3982.4 - 1.19E+06 - - - 0.6126 - 2.333 0.286 - 569.5 1 2 0 0.0008 12 0 0 0 1.68E+08 1.66E+08 - - - 3.3821 0.8977 230117_WJC_METTL3_WT_vs_EV_F06.22221.22221.2 0.0111 12-Jun K.TSFFQAL.G "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 9 812.4069 - 54255 22221 2 812.407221 407.2107 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 5.19 3982.5 - 1.17E+06 - - - 0.4505 - 1.195 0.351 - 130.6 1 1 0 0.0004 7 0 0 0 - - - - - 2.1978 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.22223.22223.2 0.000449 22-Aug R.VLGLLGALDPYK.H sp|P42345|MTOR_HUMAN 1 1257.7333 1.18 54257 22223 2 1257.734897 629.8739 Serine\threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 5.81 3982.6 - 1.10E+06 - - - 1.2896 - 1.89 0.356 - 214.5 1 2 0 0.0016 12 0 0 0 4.20E+06 3.54E+06 - - - 3.3448 0.9145 230117_WJC_METTL3_WT_vs_EV_F06.22230.22230.2 0.453 24-Jun R.EYMSPDIALLYLK.H sp|Q7RTY7|OVCH1_HUMAN 1 1554.8004 10.16 54264 22230 2 1554.807647 778.4075 Ovochymase-1 OS=Homo sapiens OX=9606 GN=OVCH1 PE=2 SV=2 4.37 3983.4 - 637353 - - - 4.6816 - 0.954 0.165 - 67.5 1 2 0 0.0073 13 0 0 0 5.87E+06 5.77E+05 - - - 0.1365 1 230117_WJC_METTL3_WT_vs_EV_F06.22234.22234.2 5.32E-11 18/30 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 -1 54267 22234 2 1751.866903 876.9399 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3983.8 - 8.98E+06 - - - 0.9989 - 3.538 0.685 - 1078.2 1 2 0 0.0018 16 0 0 0 0.00E+00 0.00E+00 - - - 7.2064 1 230117_WJC_METTL3_WT_vs_EV_F06.22235.22235.2 1.11E-05 13/22 R.NLQNLLILTAIK.A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1352.8391 1.08 54268 22235 2 1352.839719 677.4268 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3983.8 - 8.00E+06 - - - 0.4302 - 2.512 0.574 - 497.2 1 2 0 0.0006 12 0 0 0 4.45E+07 4.11E+07 - - - 5.7039 1 230117_WJC_METTL3_WT_vs_EV_F06.22236.22236.2 1.06E-06 14/22 R.NLQNLLILTAIK[136.11].A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1360.8533 1.08 54269 22236 2 1360.854682 681.4339 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3983.8 - 7.24E+06 - - - 0.9884 - 2.606 0.568 - 542.6 1 2 0 0.0013 12 0 0 0 4.45E+07 4.11E+07 - - - 5.756 1 230117_WJC_METTL3_WT_vs_EV_F06.22237.22237.3 5.96E-08 Dec-60 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 -1 54270 22237 3 1751.867523 584.9623 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3983.9 - 6.16E+06 - - - 1.3528 - 2.723 0.544 - 218.8 1 2 0 0.0024 16 0 0 0 0.00E+00 0.00E+00 - - - 7.1747 1 230117_WJC_METTL3_WT_vs_EV_F06.22239.22239.2 2.55E-07 13/20 K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 -1 54272 22239 2 1315.787341 658.9005 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3983.9 - 4.91E+06 - - - 0.7357 - 2.362 0.566 - 593.8 1 2 0 0.001 11 0 0 0 0.00E+00 0.00E+00 - - - 5.5463 1 230117_WJC_METTL3_WT_vs_EV_F06.22240.22240.2 4.26E-06 13/20 K.TLSYLLPLLQR[166.11].L sp|Q9NUL7|DDX28_HUMAN 1 1325.7946 -1 54273 22240 2 1325.796327 663.9046 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3984 - 4.81E+06 - - - 1.2702 - 2.079 0.558 - 582.3 1 2 0 0.0017 11 0 0 0 0.00E+00 0.00E+00 - - - 5.1418 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22241.22241.3 4.62E-05 Sep-52 R.LLNNAFEELVAFQR.A "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1662.873 -1 54274 22241 3 1662.872776 555.2983 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.53 3984 - 4.11E+06 - - - -0.1082 - 2.046 0.485 - 116.2 1 2 0 -0.0002 14 0 0 0 0.00E+00 0.00E+00 - - - 5.8497 1 230117_WJC_METTL3_WT_vs_EV_F06.22242.22242.2 1.16E-11 13/30 K.VGEVTYVELLMDAEGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1759.8794 -1 54275 22242 2 1759.881068 880.947 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3984.1 - 3.71E+06 - - - 0.9745 - 2.918 0.656 - 455.3 1 2 0 0.0017 16 0 0 0 0.00E+00 0.00E+00 - - - 6.5185 1 230117_WJC_METTL3_WT_vs_EV_F06.22243.22243.2 0.000432 22-Oct R.YLDFSSIITEVR.A sp|Q8N1N4|K2C78_HUMAN 1 1441.7453 -1 54276 22243 2 1441.746398 721.8799 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.37 3984.1 - 3.24E+06 - - - 0.7644 - 2.352 0.524 - 279.7 1 2 0 0.0011 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1613 1 230117_WJC_METTL3_WT_vs_EV_F06.22244.22244.2 6.14E-06 14/26 R.LLNNAFEELVAFQR.A "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1662.873 -1 54277 22244 2 1662.86227 832.4438 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.53 3984.2 - 2.73E+06 - - - -6.4262 - 2.254 0.499 - 442.8 1 2 0 -0.0107 14 0 0 0 0.00E+00 0.00E+00 - - - 4.7627 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.22245.22245.2 0.000868 28-Nov K.LGLLGLANSLAIEGR.K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1495.8722 -1 54278 22245 2 1495.873776 748.9434 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3984.2 - 2.37E+06 - - - 1.0348 - 2.182 0.427 - 191 1 2 0 0.0015 15 0 0 0 0.00E+00 0.00E+00 - - - 4.1126 1 230117_WJC_METTL3_WT_vs_EV_F06.22246.22246.2 9.03E-09 16/28 K.LTILQSLGDPLYYGK.L "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 1679.9134 -1 54279 22246 2 1679.915407 840.964 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.83 3984.3 - 2.29E+06 - - - 1.1804 - 2.824 0.594 - 819.6 1 2 0 0.002 15 0 0 0 0.00E+00 0.00E+00 - - - 5.98 1 230117_WJC_METTL3_WT_vs_EV_F06.22247.22247.2 0.000968 18-Nov K.LNMILVQILK.Q "sp|O14980|XPO1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 1183.7363 -1 54280 22247 2 1183.737857 592.8754 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3984.3 - 2.28E+06 - - - 1.3567 - 2.364 0.438 - 395.7 1 2 0 0.0016 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6771 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.22250.22250.2 0.11 18-Sep K.VLVYELLLGK.G sp|Q96P11|NSUN5_HUMAN 1 1145.706 1.89 54283 22250 2 1145.707424 573.8603 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 5.97 3984.5 - 1.94E+06 - - - 1.2455 - 1.425 0.34 - 204.4 1 2 0 0.0014 10 0 0 0 5.31E+06 2.81E+06 - - - 2.5404 0.9995 230117_WJC_METTL3_WT_vs_EV_F06.22251.22251.2 0.00335 18-Oct K.LNMILVQILK[136.11].Q "sp|O14980|XPO1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 1191.7505 -1 54284 22251 2 1191.75198 596.8825 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3984.5 - 1.70E+06 - - - 1.283 - 1.932 0.33 - 282.9 1 2 0 0.0015 10 0 0 0 0.00E+00 0.00E+00 - - - 3.3161 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.22254.22254.2 3.93E-05 20-Oct K.EYPFILDAFQR.E sp|P42285|MTREX_HUMAN 1 1397.698 -1 54286 22254 2 1397.701316 699.8563 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 3984.8 - 4.90E+06 - - - 2.4068 - 1.799 0.535 - 420.8 1 2 0 0.0034 11 0 0 0 0.00E+00 0.00E+00 - - - 4.5801 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22255.22255.3 0.000836 14/44 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 -1 54287 22255 3 1336.84829 446.6234 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3984.8 - 7.15E+06 - - - 0.0337 - 2.282 0.42 - 271 1 2 0 0 12 0 0 0 0.00E+00 0.00E+00 - - - 5.5095 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22256.22256.3 0.000177 15/44 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 1.03 54288 22256 3 1344.862654 449.2948 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3984.9 - 7.07E+06 - - - 0.1554 - 2.45 0.453 - 296 1 2 0 0.0002 12 0 0 0 1.11E+07 1.08E+07 - - - 6.0743 1 230117_WJC_METTL3_WT_vs_EV_F06.22257.22257.2 5.00E-05 15/28 R.LPFLSSSNLSLDVLR.G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1659.9196 -1 54289 22257 2 1659.919763 830.9671 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3984.9 - 6.29E+06 - - - 0.1151 - 3.163 0.528 - 852.6 1 2 0 0.0002 15 0 0 0 0.00E+00 0.00E+00 - - - 5.7718 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.22258.22258.2 6.33E-05 18-Oct K.FDTIYQILLK.K "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 1252.7067 -1 54290 22258 2 1252.706688 627.3606 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 5.83 3985 - 5.17E+06 - - - -0.0295 - 2.072 0.453 - 328.5 1 2 0 0 10 0 0 0 0.00E+00 0.00E+00 - - - 4.4204 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.22259.22259.2 0.000534 20-Oct K.EYPFILDAFQR[166.11].E sp|P42285|MTREX_HUMAN 1 1407.7062 -1 54291 22259 2 1407.708007 704.8604 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 3985 - 3.98E+06 - - - 1.268 - 2.005 0.48 - 440.2 1 2 0 0.0018 11 0 0 0 0.00E+00 0.00E+00 - - - 4.4676 1 230117_WJC_METTL3_WT_vs_EV_F06.22260.22260.2 5.25E-06 13/22 K.LGTLSALDILIK[136.11].N "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1263.7893 -1 54292 22260 2 1263.790313 632.9019 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 5.84 3985.1 - 3.83E+06 - - - 0.7707 - 2.787 0.503 - 617.4 1 2 0 0.001 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4527 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22262.22262.3 9.72E-06 15/64 K.LFEMVLGPAAYNVPLPK.K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1858.0063 1.92 54294 22262 3 1858.005612 620.3427 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6 3985.2 - 2.70E+06 - - - -0.3584 - 2.895 0.558 - 248.8 1 2 0 -0.0007 17 0 0 0 6.21E+06 3.24E+06 - - - 7.4464 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22263.22263.3 0.000569 Oct-40 K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 -1 54295 22263 3 1315.787678 439.6027 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3985.2 - 2.69E+06 - - - 0.9918 - 1.769 0.456 - 167.2 1 2 0 0.0013 11 0 0 0 0.00E+00 0.00E+00 - - - 5.244 1 230117_WJC_METTL3_WT_vs_EV_F06.22265.22265.2 6.57E-11 17/32 K.LFEMVLGPAAYNVPLPK.K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1858.0063 1.91 54297 22265 2 1858.012844 930.0104 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6 3985.4 - 2.33E+06 - - - 3.5339 - 3.553 0.611 - 917.4 1 2 0 0.0066 17 0 0 0 6.06E+06 3.18E+06 - - - 6.6687 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.22266.22266.3 0.00415 Oct-44 R.NLQNLLILTAIK.A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1352.8391 1.16 54298 22266 3 1352.83828 451.9537 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3985.5 - 2.32E+06 - - - -0.6335 - 2.057 0.404 - 199.8 1 2 0 -0.0009 12 0 0 0 3.85E+06 3.31E+06 - - - 5.0432 0.9954 230117_WJC_METTL3_WT_vs_EV_F06.22267.22267.3 0.15 Sep-40 K.TLSYLLPLLQR[166.11].L sp|Q9NUL7|DDX28_HUMAN 1 1325.7946 -1 54299 22267 3 1325.7959 442.9388 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3985.6 - 2.24E+06 - - - 0.9481 - 1.358 0.236 - 92.2 1 2 0 0.0013 11 0 0 0 0.00E+00 0.00E+00 - - - 2.0401 1 230117_WJC_METTL3_WT_vs_EV_F06.22268.22268.2 1.68E-06 14/26 R.ISLPLPNFSSLNLR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1569.8879 1.73 54300 22268 2 1569.888879 785.9512 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3985.7 - 2.15E+06 - - - 0.6376 - 2.533 0.564 - 391.5 1 2 0 0.001 14 0 0 0 1.11E+07 6.41E+06 - - - 5.5387 1 230117_WJC_METTL3_WT_vs_EV_F06.22270.22270.2 2.24E-05 13/28 K.GVFVQSVLPYFVATK.L "sp|Q53GQ0|DHB12_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN" 2 1653.913 -1 54302 22270 2 1653.908339 827.9638 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 8.59 3985.8 - 1.97E+06 - - - -2.8363 - 2.259 0.532 - 390.5 1 2 0 -0.0047 15 0 0 0 0.00E+00 0.00E+00 - - - 4.9724 1 230117_WJC_METTL3_WT_vs_EV_F06.22271.22271.2 4.05E-08 14/24 K.APDEETLIALLAH.A "sp|Q9Y3E5|PTH2_HUMAN,tr|J3KQ48|J3KQ48_HUMAN" 2 1391.7296 - 54303 22271 2 1391.731375 696.8721 "Peptidyl-tRNA hydrolase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PTRH2 PE=1 SV=1" 4.13 3985.9 - 1.95E+06 - - - 1.2423 - 2.901 0.64 - 535.2 1 1 0 0.0017 13 0 0 0 - - - - - 6.501 0.9937 230117_WJC_METTL3_WT_vs_EV_F06.22272.22272.2 0.374 Apr-38 K.MLLDPMGGIVMTNDGNAILR.E "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 2130.0636 -1 54304 22272 2 2130.06753 1066.0391 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.21 3986 - 1.89E+06 - - - 1.8675 - 0.888 0.284 - 28.8 1 2 0 0.004 20 0 0 0 0.00E+00 0.00E+00 - - - 0.8453 0.998 230117_WJC_METTL3_WT_vs_EV_F06.22274.22274.2 1.16E-05 18-Nov R.SPNDLLALFR[166.11].Y "sp|Q92626|PXDN_HUMAN,tr|H7C1W1|H7C1W1_HUMAN" 2 1154.6323 0.22 54305 22274 2 1154.629565 578.3234 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 5.55 3986.2 - 1.75E+06 - - - -2.393 - 1.781 0.463 - 247.7 1 2 0 -0.0028 10 0 0 0 5.73E+06 2.64E+07 - - - 4.0709 1 230117_WJC_METTL3_WT_vs_EV_F06.22277.22277.2 6.61E-06 13/22 K.TSDLIVLGLPWK[136.11].T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1348.7846 -1 54308 22277 2 1348.787137 675.3996 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3986.4 - 6.70E+06 - - - 1.8898 - 2.429 0.512 - 616.8 1 2 0 0.0025 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1569 1 230117_WJC_METTL3_WT_vs_EV_F06.22281.22281.2 1.39E-07 14/26 R.VISGVLQLGNIVFK[136.11].K sp|P35579|MYH9_HUMAN 1 1493.9061 -1 54312 22281 2 1493.908312 747.9603 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.72 3986.7 - 1.89E+06 - - - 1.48 - 2.948 0.603 - 455.7 1 2 0 0.0022 14 0 0 0 0.00E+00 0.00E+00 - - - 6.2071 0.9985 230117_WJC_METTL3_WT_vs_EV_F06.22286.22286.2 0.0365 22-Jul K.NVLITDFFGSVR.K "sp|Q92643|GPI8_HUMAN,tr|B1AK81|B1AK81_HUMAN,tr|A6NEM5|A6NEM5_HUMAN" 3 1366.7245 -1 54317 22286 2 1366.728844 684.3695 GPI-anchor transamidase OS=Homo sapiens OX=9606 GN=PIGK PE=1 SV=2 5.84 3987.1 - 1.16E+06 - - - 3.1777 - 1.809 0.291 - 149.9 1 2 0 0.0043 12 0 0 0 0.00E+00 0.00E+00 - - - 2.7487 1 230117_WJC_METTL3_WT_vs_EV_F06.22288.22288.2 1.93E-10 20/32 R.AFLQGGQEATDIALLLR.D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1814.989 -1 54319 22288 2 1814.991916 908.5018 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3987.4 - 1.00E+06 - - - 1.5802 - 3.791 0.665 - 1343.4 1 2 0 0.0029 17 0 0 0 0.00E+00 0.00E+00 - - - 7.2281 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.22289.22289.2 5.59E-05 13/26 R.ISLPLPNFSSLNLR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1579.8961 1.73 54320 22289 2 1579.899555 790.9554 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3987.5 - 864462 - - - 2.1565 - 2.035 0.507 - 429.2 1 2 0 0.0034 14 0 0 0 1.11E+07 6.41E+06 - - - 4.5676 1 230117_WJC_METTL3_WT_vs_EV_F06.22290.22290.2 3.27E-08 16/24 R.DPTYFGPVLNYLR[166.11].H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1563.7961 0.97 54321 22290 2 1563.80574 782.9053 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3987.6 - 861231 - - - 6.1651 - 2.667 0.612 - 986.1 1 2 0 0.0096 13 0 0 0 6.61E+06 6.83E+06 - - - 6.0759 1 230117_WJC_METTL3_WT_vs_EV_F06.22291.22291.2 0.00012 14/24 R.DPTYFGPVLNYLR.H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1553.7878 0.97 54322 22291 2 1553.790828 777.9012 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3987.8 - 853626 - - - 1.9301 - 2.783 0.562 - 747.1 1 2 0 0.003 13 0 0 0 6.61E+06 6.83E+06 - - - 5.8179 0.9516 230117_WJC_METTL3_WT_vs_EV_F06.22297.22297.2 0.00362 18-Jul E.QEEDISSLIR.S sp|P78527|PRKDC_HUMAN 1 1188.5986 8.15 54327 22297 2 1188.600622 595.3066 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.14 3988.4 - 1.22E+07 - - - 1.6742 - 1.469 0.381 - 153.3 1 1 0 0.002 10 0 0 0 2.59E+07 3.18E+06 - - - 2.9279 1 230117_WJC_METTL3_WT_vs_EV_F06.22301.22301.2 3.81E-06 20-Dec R.VLDLVEVLVTK[136.11].Q "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1234.7628 -1 54331 22301 2 1234.764928 618.3887 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.37 3988.7 - 1.58E+06 - - - 1.7315 - 2.653 0.595 - 429.9 1 2 0 0.0021 11 0 0 0 0.00E+00 0.00E+00 - - - 6.0745 0.903 230117_WJC_METTL3_WT_vs_EV_F06.22303.22303.2 0.0103 18-Jul E.QEEDISSLIR[166.11].S sp|P78527|PRKDC_HUMAN 1 1198.6069 -1 54333 22303 2 1198.608792 600.3107 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.14 3988.8 - 1.41E+06 - - - 1.5768 - 1.364 0.296 - 126 1 1 0 0.0019 10 0 0 0 0.00E+00 0.00E+00 - - - 2.0931 1 230117_WJC_METTL3_WT_vs_EV_F06.22306.22306.2 6.79E-08 13/22 K.FFDDPMLLELAK.Q "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1437.7214 1.65 54336 22306 2 1437.72213 719.868 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.03 3989.1 - 1.24E+06 - - - 0.5154 - 2.531 0.536 - 312.2 1 2 0 0.0007 12 0 0 0 1.13E+07 6.84E+06 - - - 5.443 1 230117_WJC_METTL3_WT_vs_EV_F06.22308.22308.3 9.80E-05 20/72 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 54338 22308 3 1911.183485 638.0676 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3989.3 - 954429 - - - 1.3672 - 3.43 0.54 - 527 1 2 0 0.0026 19 0 0 0 0.00E+00 0.00E+00 - - - 7.5879 1 230117_WJC_METTL3_WT_vs_EV_F06.22309.22309.2 3.86E-07 15/24 R.AIAYLFPSGLFEK[136.11].R sp|P82933|RT09_HUMAN 1 1462.7952 1.14 54339 22309 2 1462.79769 732.4049 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 6.05 3989.5 - 809445 - - - 1.7344 - 3.077 0.407 - 884.4 1 2 0 0.0025 13 0 0 0 1.29E+07 1.13E+07 - - - 4.931 1 230117_WJC_METTL3_WT_vs_EV_F06.22310.22310.2 0.02 15/36 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 54340 22310 2 1911.185117 956.5977 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3989.6 - 717096 - - - 2.2211 - 2.661 0.476 - 442.8 1 2 0 0.0042 19 0 0 0 0.00E+00 0.00E+00 - - - 4.9616 0.8931 230117_WJC_METTL3_WT_vs_EV_F06.22313.22313.2 0.134 18-Jul K.VEDLTFTSPF.C "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1154.5496 - 54343 22313 2 1154.551995 578.2821 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 3.67 3989.9 - 640593 - - - 2.1125 - 1.368 0.298 - 121 1 1 0 0.0024 10 0 0 0 - - - - - 2.1159 1 230117_WJC_METTL3_WT_vs_EV_F06.22314.22314.2 4.24E-07 13/32 R.AFLQGGQEATDIALLLR[166.11].D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1824.9973 -1 54344 22314 2 1824.998487 913.5059 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3990.1 - 636831 - - - 0.6405 - 2.606 0.588 - 449.2 1 2 0 0.0012 17 0 0 0 0.00E+00 0.00E+00 - - - 5.7384 0.9792 230117_WJC_METTL3_WT_vs_EV_F06.22321.22321.2 1.81 18-May R.C[160.03]FSTTLLYC[160.03]R.K sp|P60893|GPR85_HUMAN 1 1319.6002 137.68 54350 22321 2 1319.600011 660.8074 Probable G-protein coupled receptor 85 OS=Homo sapiens OX=9606 GN=GPR85 PE=1 SV=1 8.06 3990.6 - 4.87E+06 - - - -0.1652 - 1.108 0.131 - 58 1 2 0 -0.0002 10 0 0 0 1.87E+07 1.36E+05 - - - 0.2948 1 230117_WJC_METTL3_WT_vs_EV_F06.22322.22322.2 8.98E-13 16/26 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 -1 54351 22322 2 1537.770051 769.8922 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3990.6 - 4.66E+06 - - - 0.1658 - 3.241 0.7 - 796 1 2 0 0.0003 14 0 0 0 0.00E+00 0.00E+00 - - - 7.1619 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.22324.22324.3 0.000286 Nov-48 R.GNTAAYLLYAFTR.L sp|P54136|SYRC_HUMAN 1 1459.746 -1 54353 22324 3 1459.749272 487.5893 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.59 3990.8 - 2.17E+06 - - - 2.2655 - 1.886 0.363 - 120.7 1 2 0 0.0033 13 0 0 0 0.00E+00 0.00E+00 - - - 4.3064 0.9915 230117_WJC_METTL3_WT_vs_EV_F06.22327.22327.2 0.00842 22-Nov K.AGGSFLALVLAR[166.11].A "sp|Q8WVS4|DC2I1_HUMAN,tr|H7C1E8|H7C1E8_HUMAN" 2 1183.6953 4.17 54356 22327 2 1183.698532 592.8549 Cytoplasmic dynein 2 intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC2I1 PE=1 SV=3 9.79 3991 - 1.83E+06 - - - 2.7617 - 1.557 0.097 - 181.9 1 2 0 0.0033 12 0 0 0 1.53E+07 3.68E+06 - - - 0.9214 0.9987 230117_WJC_METTL3_WT_vs_EV_F06.22328.22328.2 0.0317 14/26 K.TLAESALQLLYTAK.E sp|Q9Y490|TLN1_HUMAN 1 1520.845 -1 54357 22328 2 1520.847944 761.4298 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.66 3991.1 - 1.79E+06 - - - 1.9292 - 1.516 0.282 - 424.4 1 2 0 0.0029 14 0 0 0 0.00E+00 0.00E+00 - - - 2.1671 0.9941 230117_WJC_METTL3_WT_vs_EV_F06.22332.22332.3 0.061 Aug-48 R.GNTAAYLLYAFTR[166.11].L sp|P54136|SYRC_HUMAN 1 1469.7542 -1 54361 22332 3 1469.756406 490.9254 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.59 3991.4 - 1.29E+06 - - - 1.4771 - 1.586 0.186 - 79.6 1 2 0 0.0022 13 0 0 0 0.00E+00 0.00E+00 - - - 1.8636 1 230117_WJC_METTL3_WT_vs_EV_F06.22334.22334.2 0.000109 24-Oct R.GNTAAYLLYAFTR[166.11].L sp|P54136|SYRC_HUMAN 1 1469.7542 -1 54363 22334 2 1469.756436 735.8844 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.59 3991.6 - 1.22E+06 - - - 1.4975 - 2.316 0.466 - 265.7 1 2 0 0.0022 13 0 0 0 0.00E+00 0.00E+00 - - - 4.6377 1 230117_WJC_METTL3_WT_vs_EV_F06.22338.22338.2 0.000181 15/28 R.ATSFLLALEPELEAR.L "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1658.8879 -1 54366 22338 2 1658.886563 830.4512 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.25 3992 - 2.38E+06 - - - -0.8283 - 2.879 0.565 - 766.7 1 2 0 -0.0014 15 0 0 0 0.00E+00 0.00E+00 - - - 5.8134 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22340.22340.3 0.00121 Sep-52 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 -1 54368 22340 3 1537.772233 513.5972 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3992 - 7.02E+06 - - - 1.5848 - 2.375 0.454 - 141.2 1 2 0 0.0024 14 0 0 0 0.00E+00 0.00E+00 - - - 5.8997 1 230117_WJC_METTL3_WT_vs_EV_F06.22341.22341.3 1.79E-06 15/56 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 2.02 54369 22341 3 1519.910863 507.6435 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3992.1 - 5.01E+06 - - - 1.4804 - 2.747 0.579 - 301.4 1 2 0 0.0022 15 0 0 0 1.20E+07 5.94E+06 - - - 7.6314 1 230117_WJC_METTL3_WT_vs_EV_F06.22343.22343.2 4.05E-07 18/28 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 2.61 54371 22343 2 1519.911064 760.9616 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3992.2 - 2.97E+06 - - - 1.6126 - 2.954 0.586 - 1348.7 1 2 0 0.0024 15 0 0 0 8.15E+06 3.12E+06 - - - 6.0314 1 230117_WJC_METTL3_WT_vs_EV_F06.22345.22345.2 5.84E-07 13/22 K.AYVVLGQFLVLK[136.11].K sp|O75531|BAF_HUMAN 1 1356.8261 -1 54373 22345 2 1356.828187 679.4203 Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1 8.63 3992.3 - 2.40E+06 - - - 1.5684 - 2.66 0.619 - 585.9 1 2 0 0.0021 12 0 0 0 0.00E+00 0.00E+00 - - - 6.1864 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22346.22346.3 0.00464 13/56 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 2.02 54374 22346 3 1529.919034 510.9796 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3992.4 - 2.30E+06 - - - 1.406 - 2.327 0.414 - 175.3 1 2 0 0.0022 15 0 0 0 1.20E+07 5.94E+06 - - - 5.3589 1 230117_WJC_METTL3_WT_vs_EV_F06.22348.22348.2 5.74E-10 22-Nov K.NTPFLYDLVMTH.A "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|E9PIC4|E9PIC4_HUMAN,tr|E9PNS2|E9PNS2_HUMAN,tr|E9PNS6|E9PNS6_HUMAN,tr|C9JAJ9|C9JAJ9_HUMAN,tr|E9PC52|E9PC52_HUMAN" 7 1449.6962 - 54376 22348 2 1449.698689 725.8554 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.08 3992.5 - 2.03E+06 - - - 1.6914 - 2.436 0.65 - 489.5 1 1 0 0.0025 12 0 0 0 - - - - - 6.1838 1 230117_WJC_METTL3_WT_vs_EV_F06.22350.22350.2 5.85E-06 28-Dec R.ATSFLLALEPELEAR[166.11].L "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1668.8962 -1 54378 22350 2 1668.897638 835.4554 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.25 3992.6 - 1.72E+06 - - - 0.8575 - 2.676 0.521 - 464.7 1 2 0 0.0014 15 0 0 0 0.00E+00 0.00E+00 - - - 5.3087 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22351.22351.3 0.000999 19/60 K.IFEIFGPVAHPFYVLR.F sp|Q96HR8|NAF1_HUMAN 1 1904.0349 -1 54379 22351 3 1904.038732 635.6856 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 6.75 3992.7 - 1.65E+06 - - - 2.0252 - 3.185 0.426 - 510 1 2 0 0.0039 16 0 0 0 0.00E+00 0.00E+00 - - - 6.2608 0.9993 230117_WJC_METTL3_WT_vs_EV_F06.22352.22352.2 0.00111 22-Sep K.AYVVLGQFLVLK.K sp|O75531|BAF_HUMAN 1 1348.8119 -1 54380 22352 2 1348.81488 675.4132 Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1 8.63 3992.8 - 1.44E+06 - - - 2.2397 - 1.765 0.342 - 247.5 1 2 0 0.003 12 0 0 0 0.00E+00 0.00E+00 - - - 3.061 0.9984 230117_WJC_METTL3_WT_vs_EV_F06.22353.22353.2 0.103 20-Aug K.IADFGFGNFFK.S sp|Q9H0K1|SIK2_HUMAN 1 1261.6132 -1 54381 22353 2 1261.614522 631.8139 Serine\threonine-protein kinase SIK2 OS=Homo sapiens OX=9606 GN=SIK2 PE=1 SV=1 5.84 3992.9 - 1.33E+06 - - - 1.0804 - 1.548 0.228 - 187.9 1 2 0 0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 1.9067 1 230117_WJC_METTL3_WT_vs_EV_F06.22354.22354.2 8.74E-08 17/28 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 -1 54382 22354 2 1529.919913 765.9657 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3993 - 1.20E+06 - - - 1.9805 - 2.903 0.577 - 877.7 1 2 0 0.003 15 0 0 0 0.00E+00 0.00E+00 - - - 5.922 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.22360.22360.2 0.224 16-Jul K.LLLPWLEAR.L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1109.6597 -1 54387 22360 2 1109.661814 555.8371 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6 3993.6 - 1.51E+07 - - - 1.8907 - 1.564 0.279 - 222 1 2 0 0.0021 9 0 0 0 0.00E+00 0.00E+00 - - - 2.3949 1 230117_WJC_METTL3_WT_vs_EV_F06.22361.22361.2 8.02E-06 18-Oct R.C[160.03]WAGSLWLFK[136.11].D sp|Q9BQA1|MEP50_HUMAN 1 1274.6362 0.45 54388 22361 2 1274.638564 638.3254 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 3993.7 - 6.09E+06 - - - 1.8939 - 2.015 0.525 - 289.9 1 2 0 0.0024 10 0 0 0 1.54E+07 3.44E+07 - - - 4.8735 1 230117_WJC_METTL3_WT_vs_EV_F06.22362.22362.2 5.22E-08 18-Oct R.C[160.03]WAGSLWLFK.D sp|Q9BQA1|MEP50_HUMAN 1 1266.6219 -1 54389 22362 2 1266.625269 634.3183 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 3993.7 - 2.22E+06 - - - 2.6204 - 2.187 0.587 - 272.7 1 2 0 0.0033 10 0 0 0 0.00E+00 0.00E+00 - - - 5.5598 1 230117_WJC_METTL3_WT_vs_EV_F06.22364.22364.2 0.000156 24-Dec K.TVYVSVLPTTADF.- "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN" 4 1411.7235 - 54391 22364 2 1411.726422 706.869 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 3.8 3993.9 - 1.52E+06 - - - 2.0712 - 2.182 0.51 - 497 1 2 0 0.0029 13 0 0 0 - - - - - 4.8095 1 230117_WJC_METTL3_WT_vs_EV_F06.22366.22366.3 5.72E-08 15/52 R.HPYFYAPELLFFAK.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 1741.8868 22.51 54393 22366 3 1741.894925 581.6362 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6.75 3994 - 1.13E+06 - - - 4.6559 - 2.946 0.569 - 387 1 2 0 0.0081 14 0 0 0 4.03E+06 1.79E+05 - - - 7.7529 0.9948 230117_WJC_METTL3_WT_vs_EV_F06.22368.22368.2 0.0302 18-Aug R.GFGFVDFLTK[136.11].Q "sp|Q9Y4C8|RBM19_HUMAN,tr|H0YIL2|H0YIL2_HUMAN" 2 1137.595 -1 54395 22368 2 1137.598469 569.8048 Probable RNA-binding protein 19 OS=Homo sapiens OX=9606 GN=RBM19 PE=1 SV=3 5.84 3994.2 - 934412 - - - 3.0521 - 1.355 0.211 - 85.4 1 2 0 0.0035 10 0 0 0 0.00E+00 0.00E+00 - - - 1.4464 1 230117_WJC_METTL3_WT_vs_EV_F06.22370.22370.3 1.28E-08 18/44 K.FFEVILIDPFHK[136.11].A "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 4 1511.8268 -1 54397 22370 3 1511.829662 504.9495 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 5.32 3994.4 - 839798 - - - 1.901 - 2.763 0.576 - 332.2 1 2 0 0.0029 12 0 0 0 0.00E+00 0.00E+00 - - - 7.7781 0.9989 230117_WJC_METTL3_WT_vs_EV_F06.22375.22375.2 8.75E-05 24-Sep K.LVDQNIFSFYLSR.D "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1600.8249 -1 54402 22375 2 1600.823129 801.4197 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.84 3995 - 740744 - - - -1.1332 - 2.054 0.389 - 150.1 1 2 0 -0.0018 13 0 0 0 0.00E+00 0.00E+00 - - - 3.7609 1 230117_WJC_METTL3_WT_vs_EV_F06.22381.22381.3 1.72E-07 15/44 K.FFEVILIDPFHK.A "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 4 1503.8126 0.85 54407 22381 3 1503.816358 502.2781 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 5.32 3995.6 - 2.69E+06 - - - 2.507 - 2.682 0.588 - 271.4 1 2 0 0.0038 12 0 0 0 5.81E+06 6.82E+06 - - - 7.8292 1 230117_WJC_METTL3_WT_vs_EV_F06.22382.22382.2 1.09E-06 17/24 R.DLYEDELVPLFEK[136.11].A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1616.8065 -1 54408 22382 2 1616.810424 809.4105 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3995.7 - 2.48E+06 - - - 2.4233 - 2.929 0.621 - 806.7 1 2 0 0.0039 13 0 0 0 0.00E+00 0.00E+00 - - - 6.3846 0.9991 230117_WJC_METTL3_WT_vs_EV_F06.22384.22384.2 0.0081 18-Nov R.AALLELWELR[166.11].R "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1222.6949 -1 54410 22384 2 1222.69965 612.3547 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 3995.9 - 1.10E+06 - - - 3.8611 - 2.648 0.34 - 429.2 1 2 0 0.0047 10 0 0 0 0.00E+00 0.00E+00 - - - 4.2689 0.9997 230117_WJC_METTL3_WT_vs_EV_F06.22385.22385.2 0.000653 13/24 R.DILVEADSLWVVK[136.11].M sp|Q15208|STK38_HUMAN 1 1493.8221 -1 54411 22385 2 1493.825383 747.9183 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.03 3996 - 897335 - - - 2.2004 - 2.645 0.362 - 441.2 1 2 0 0.0033 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2101 1 230117_WJC_METTL3_WT_vs_EV_F06.22388.22388.2 1.13E-08 19/30 K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 -1 54414 22388 2 1701.891931 851.9512 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3996.3 - 818169 - - - 2.3815 - 3.15 0.601 - 844.9 1 2 0 0.0041 16 0 0 0 0.00E+00 0.00E+00 - - - 6.2997 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22389.22389.3 3.71E-05 Dec-48 R.DLYEDELVPLFEK[136.11].A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1616.8065 -1 54415 22389 3 1616.8113 539.9428 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3996.4 - 737297 - - - 2.9651 - 2.24 0.486 - 240.1 1 2 0 0.0048 13 0 0 0 0.00E+00 0.00E+00 - - - 6.1437 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22395.22395.3 0.000196 14/48 R.DLYEDELVPLFEK.A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1608.7923 0.82 54421 22395 3 1608.796268 537.2714 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3997.2 - 560585 - - - 2.4627 - 2.508 0.387 - 337.7 1 2 0 0.004 13 0 0 0 1.58E+06 1.93E+06 - - - 5.3466 0.9994 230117_WJC_METTL3_WT_vs_EV_F06.22397.22397.2 0.00264 16-Sep K.AFLLESLLK.N sp|Q96JM3|CHAP1_HUMAN 1 1032.6219 4.09 54423 22397 2 1032.624558 517.3182 Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2 6.05 3997.4 - 529074 - - - 2.5421 - 1.917 0.361 - 259.7 1 2 0 0.0026 9 0 0 0 5.88E+06 1.44E+06 - - - 3.5892 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22400.22400.3 0.000315 Sep-52 K.ILGGSVLHLVLALR.G sp|Q15843|NEDD8_HUMAN 1 1459.9239 -1 54425 22400 3 1459.926998 487.6486 NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1 9.76 3997.8 - 204634 - - - 2.1433 - 2.138 0.427 - 80.4 1 2 0 0.0031 14 0 0 0 0.00E+00 0.00E+00 - - - 5.3191 1 230117_WJC_METTL3_WT_vs_EV_F06.22403.22403.2 1.20E-05 16/30 K.AAGVNVEPFWPGLFAK[136.11].A sp|P05386|RLA1_HUMAN 1 1709.9021 -1 54428 22403 2 1709.906691 855.9583 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3998 - 2.74E+06 - - - 2.6978 - 3.199 0.583 - 656.8 1 2 0 0.0046 16 0 0 0 0.00E+00 0.00E+00 - - - 6.2045 0.999 230117_WJC_METTL3_WT_vs_EV_F06.22406.22406.2 9.68E-05 18-Jul R.DGFIDLMELK.L "sp|Q96C19|EFHD2_HUMAN,sp|Q9BUP0|EFHD1_HUMAN,tr|A0A087X1Z2|A0A087X1Z2_HUMAN,tr|H0Y4Y4|H0Y4Y4_HUMAN" 4 1179.5846 -1 54431 22406 2 1179.588495 590.7996 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 4.03 3998.3 - 1.35E+06 - - - 3.3351 - 1.648 0.401 - 104.4 1 2 0 0.0039 10 0 0 0 0.00E+00 0.00E+00 - - - 3.396 0.9184 230117_WJC_METTL3_WT_vs_EV_F06.22407.22407.2 0.012 16-Jul K.QDAVDYLTW.T sp|O75643|U520_HUMAN 1 1109.5029 - 54432 22407 2 1109.506558 555.7587 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 3.56 3998.4 - 1.16E+06 - - - 3.2609 - 1.197 0.489 - 136.3 1 1 0 0.0036 9 0 0 0 - - - - - 3.1718 0.9999 230117_WJC_METTL3_WT_vs_EV_F06.22409.22409.3 1.48E-06 17/60 K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 -1 54434 22409 3 1701.893576 568.3032 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3998.6 - 1.03E+06 - - - 3.348 - 3.041 0.493 - 263.9 1 2 0 0.0057 16 0 0 0 0.00E+00 0.00E+00 - - - 6.8886 1 230117_WJC_METTL3_WT_vs_EV_F06.22411.22411.2 7.63E-07 15/26 R.DYLHLPPEIVPATL.H "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1576.8501 - 54436 22411 2 1576.855231 789.4323 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.35 3998.8 - 836873 - - - 3.2571 - 2.576 0.587 - 689.6 1 1 0 0.0051 14 0 0 0 - - - - - 5.7495 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.22413.22413.3 0.0068 13/52 K.VVLLEDLASQVGLR[166.11].T "sp|Q96HY6|DDRGK_HUMAN,tr|A0A0A0MRX2|A0A0A0MRX2_HUMAN" 2 1520.8802 -1 54438 22413 3 1520.883149 507.9673 DDRGK domain-containing protein 1 OS=Homo sapiens OX=9606 GN=DDRGK1 PE=1 SV=2 4.37 3999 - 758797 - - - 1.9633 - 1.919 0.335 - 241.1 1 2 0 0.003 14 0 0 0 0.00E+00 0.00E+00 - - - 4.0063 1 230117_WJC_METTL3_WT_vs_EV_F06.22414.22414.2 4.76E-06 26-Nov K.VVLLEDLASQVGLR.T "sp|Q96HY6|DDRGK_HUMAN,tr|A0A0A0MRX2|A0A0A0MRX2_HUMAN" 2 1510.8719 2.57 54439 22414 2 1510.876364 756.4432 DDRGK domain-containing protein 1 OS=Homo sapiens OX=9606 GN=DDRGK1 PE=1 SV=2 4.37 3999.1 - 634077 - - - 2.9592 - 2.63 0.523 - 408.9 1 2 0 0.0045 14 0 0 0 1.63E+06 6.35E+05 - - - 5.3291 1 230117_WJC_METTL3_WT_vs_EV_F06.22445.22445.2 1.93E-11 15/32 R.WVGGPEIELIAIATGGR.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1737.9414 -1 54460 22445 2 1737.952178 869.978 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 4001.3 - 496498 - - - 6.2189 - 2.894 0.574 - 624 1 2 0 0.0108 17 0 0 0 0.00E+00 0.00E+00 - - - 5.8897 0.9108 230117_WJC_METTL3_WT_vs_EV_F06.22452.22452.3 0.134 Oct-56 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 -1 54467 22452 3 1581.921718 528.3103 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4002.2 - 332865 - - - 8.0352 - 1.472 0.284 - 23 3 2 0 0.0127 15 0 0 0 0.00E+00 0.00E+00 - - - 2.4908 0.9831 230117_WJC_METTL3_WT_vs_EV_F06.23094.23094.2 0.167 16-Sep R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.44 54502 23094 2 1108.661228 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4123.2 - 3.48E+06 - - - 7.2115 - 1.979 0.271 - 220.8 1 2 0 0.008 9 0 0 0 9.79E+07 6.80E+07 - - - 3.0149 0.9653 230117_WJC_METTL3_WT_vs_EV_F06.23095.23095.2 0.173 16-Jun R.IAIYELLFK[136.11].E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1116.6674 1.44 54503 23095 2 1116.6745 559.341 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4123.3 - 2.33E+06 - - - 6.3287 - 1.383 0.231 - 92.9 1 2 0 0.0071 9 0 0 0 9.79E+07 6.80E+07 - - - 1.683 0.9935 230117_WJC_METTL3_WT_vs_EV_F06.23119.23119.2 0.229 28-May R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 8.43 54520 23119 2 1581.915422 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4125.5 - 75853.5 - - - 4.0552 - 1.465 0.249 - 69.1 1 2 0 0.0064 15 0 0 0 4.68E+06 5.55E+05 - - - 1.8169 0.9929 230117_WJC_METTL3_WT_vs_EV_F06.23143.23143.2 0.00128 20-Oct K.GIVLLEELLPK.G sp|Q9Y3D6|FIS1_HUMAN 1 1222.7537 1.42 54525 23143 2 1222.762276 612.3841 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 4.53 4129 - 3.04E+06 - - - 7.0333 - 2.155 0.446 - 414.7 1 2 0 0.0086 11 0 0 0 5.63E+06 3.96E+06 - - - 4.4095 0.9672 230117_WJC_METTL3_WT_vs_EV_F06.23148.23148.3 0.539 Aug-52 R.LISQIVSSITASLR.F "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1486.8719 -1 54530 23148 3 1486.872453 496.6312 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 9.75 4129.4 - 940228 - - - 0.3766 - 1.235 0.155 - 58.4 1 2 0 0.0006 14 0 0 0 0.00E+00 0.00E+00 - - - 0.8289 0.9981 230117_WJC_METTL3_WT_vs_EV_F06.23149.23149.2 0.185 26-Jun R.LLVPTQFVGAIIGK.E "sp|O00425|IF2B3_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 3 1454.8861 1.09 54531 23149 2 1454.885694 728.4503 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 4129.5 - 786366 - - - -0.2701 - 1.149 0.395 - 83.4 1 2 0 -0.0004 14 0 0 0 1.55E+06 1.43E+06 - - - 2.3069 0.9961 230117_WJC_METTL3_WT_vs_EV_F06.23151.23151.2 0.0589 22-Apr R.TFC[160.03]QLILDPIFK.V sp|P13639|EF2_HUMAN 1 1493.7952 2.71 54533 23151 2 1493.795244 747.9049 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.5 4129.7 - 690779 - - - 0.0141 - 0.916 0.36 - 47.1 1 2 0 0 12 0 0 0 1.33E+06 4.90E+05 - - - 1.4691 1 230117_WJC_METTL3_WT_vs_EV_F06.23152.23152.2 1.07E-05 28-Oct K.FDVILLEPPLEEYYR.E "sp|Q9HCE5|MET14_HUMAN,tr|D6RBL4|D6RBL4_HUMAN" 2 1894.9717 -1 54534 23152 2 1894.974058 948.4931 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4 4129.8 - 631472 - - - 1.2618 - 2.228 0.516 - 248.6 1 2 0 0.0024 15 0 0 0 0.00E+00 0.00E+00 - - - 4.821 0.9857 230117_WJC_METTL3_WT_vs_EV_F06.23154.23154.2 0.00546 18-Jun R.DEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1329.6605 1.57 54536 23154 2 1329.655266 665.8375 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 4130.1 - 619054 - - - -3.9394 - 1.254 0.394 - 140.8 1 2 0 -0.0052 10 0 0 0 9.99E+05 6.38E+05 - - - 2.5812 0.9976 230117_WJC_METTL3_WT_vs_EV_F06.23341.23341.2 0.0118 26-Jun K.ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1626.98 1.57 54556 23341 2 1626.985784 814.4973 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4165.2 - 74598.8 - - - 3.5587 - 1.486 0.328 - 70.8 1 2 0 0.0058 14 0 0 0 1.61E+07 1.03E+07 - - - 2.4558 0.9836 230117_WJC_METTL3_WT_vs_EV_F06.23350.23350.2 0.000396 24-Jul K.SLEEIYLFSLPIK.E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN,tr|H3BNG3|H3BNG3_HUMAN,tr|H0YE27|H0YE27_HUMAN" 7 1550.8596 0.26 54562 23350 2 1550.871488 776.4371 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.53 4166.3 - 41387.1 - - - 7.6674 - 1.434 0.462 - 124.8 1 2 0 0.0119 13 0 0 0 1.11E+06 4.19E+06 - - - 3.3747 0.9956 230117_WJC_METTL3_WT_vs_EV_F06.23357.23357.2 0.0255 Apr-32 R.WVGGPEIELIAIATGGR.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1737.9414 14.05 54565 23357 2 1737.94406 869.978 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 4167.3 - 17470.6 - - - 1.5478 - 0.971 0.285 - 37.1 1 2 0 0.0027 17 0 0 0 6.90E+05 4.91E+04 - - - 1.0728 0.9996 230117_WJC_METTL3_WT_vs_EV_F06.23464.23464.2 0.000233 16-Dec R.IAIYELLFK[136.11].E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1116.6674 1.49 54583 23464 2 1116.669405 559.341 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4185.1 - 22631.9 - - - 1.766 - 2.36 0.289 - 403.5 1 2 0 0.002 9 0 0 0 6.88E+07 4.61E+07 - - - 3.6591 0.9965 230117_WJC_METTL3_WT_vs_EV_F06.23467.23467.2 0.289 16-May R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.49 54584 23467 2 1108.65595 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4185.6 - 45703.9 - - - 2.4507 - 1.124 0.286 - 67.7 1 2 0 0.0027 9 0 0 0 6.89E+07 4.62E+07 - - - 1.4907 0.9948 230117_WJC_METTL3_WT_vs_EV_F06.23500.23500.2 0.269 26-Apr K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.57 54590 23500 2 1618.970396 810.4902 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4191 - 0 - - - 2.8426 - 1.032 0.301 - 27.3 1 2 0 0.0046 14 0 0 0 1.61E+07 1.03E+07 - - - 1.3418 0.9061 230117_WJC_METTL3_WT_vs_EV_F07.02839.02839.2 0.257 14-May K.TVDGPSGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 759.3763 2.86 54610 2839 2 759.375381 380.6954 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.5 1266 - 113360 - - - -1.1878 - 0.791 0.182 - 59.4 1 2 0 -0.0009 8 0 0 0 8.33E+06 2.91E+06 - - - -0.3221 0.9254 230117_WJC_METTL3_WT_vs_EV_F07.02981.02981.2 0.393 12-Jun K.ATVEDEK.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 790.3709 3.65 54613 2981 2 790.368582 396.1927 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 1291.7 - 108016 - - - -2.886 - 0.882 0.259 - 91 1 2 0 -0.0023 7 0 0 0 3.86E+06 1.06E+06 - - - 0.5554 0.9527 230117_WJC_METTL3_WT_vs_EV_F07.03450.03450.2 0.116 12-Jun K.HPELADK.N "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 808.4079 1.57 54619 3450 2 808.404813 405.2112 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 5.32 1375.2 - 260580 - - - -3.8409 - 1.286 0.207 - 100.1 1 2 0 -0.0031 7 0 0 0 1.34E+07 8.53E+06 - - - 1.3659 0.9005 230117_WJC_METTL3_WT_vs_EV_F07.03550.03550.2 11.9 12-Apr K.LAEQAER.Y "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|I3L0W5|I3L0W5_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB1|A2IDB1_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|F8WEB6|F8WEB6_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 22 815.4137 2.33 54621 3550 2 815.412526 408.7141 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.53 1392.8 - 140550 - - - -1.4778 - 1.048 0.095 - 48.8 2 2 0 -0.0012 7 0 0 0 2.54E+06 1.09E+06 - - - -0.2436 0.9462 230117_WJC_METTL3_WT_vs_EV_F07.03977.03977.2 1.24 12-Jun R.ITPEEAK[136.11].Y sp|P62701|RS4X_HUMAN 1 794.4265 0.83 54633 3977 2 794.42575 398.2205 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.53 1468.3 - 207856 - - - -0.9869 - 1.019 0.119 - 159 1 2 0 -0.0008 7 0 0 0 1.10E+07 1.33E+07 - - - -0.0207 0.995 230117_WJC_METTL3_WT_vs_EV_F07.04087.04087.2 0.0346 12-Jul R.NSTIPTK.Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 759.4127 9.03 54640 4087 2 759.412013 380.7136 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 1487.3 - 399193 - - - -0.8638 - 1.335 0.238 - 209.6 1 2 0 -0.0007 7 0 0 0 3.16E+07 3.50E+06 - - - 1.7142 0.9962 230117_WJC_METTL3_WT_vs_EV_F07.04112.04112.2 0.864 12-Jun R.FTDEESR[166.11].V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 892.3802 0.72 54643 4112 2 892.379848 447.1974 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1491.6 - 854468 - - - -0.39 - 1.206 0.278 - 117.2 1 2 0 -0.0003 7 0 0 0 2.63E+07 3.65E+07 - - - 1.6877 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.04116.04116.2 0.00623 18-Aug R.IAGQVAAANK.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 941.5294 1.52 54644 4116 2 941.529703 471.772 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1492.2 - 135328 - - - 0.29 - 1.632 0.267 - 152.6 1 2 0 0.0003 10 0 0 0 1.66E+07 1.09E+07 - - - 2.3802 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.04194.04194.2 0.00648 14-Aug R.NTEEEGLK[136.11].Y "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 926.4436 1.35 54648 4194 2 926.441589 464.2291 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.25 1505.7 - 819856 - - - -2.2149 - 1.638 0.39 - 391.5 1 2 0 -0.0021 8 0 0 0 3.88E+07 2.88E+07 - - - 3.4092 0.9912 230117_WJC_METTL3_WT_vs_EV_F07.04218.04218.2 0.358 12-Jun R.EAQVNVR[166.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 824.438 0.05 54649 4218 2 824.43771 413.2263 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1509.9 - 646259 - - - -0.3348 - 1.207 0.182 - 268.8 1 2 0 -0.0003 7 0 0 0 2.02E+07 3.68E+08 - - - 0.9813 0.9941 230117_WJC_METTL3_WT_vs_EV_F07.04220.04220.2 0.254 12-Jun R.EAQVNVR.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 814.4297 0.06 54650 4220 2 814.428885 408.2221 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1510.1 - 478747 - - - -1.0203 - 1.232 0.264 - 214.9 1 2 0 -0.0008 7 0 0 0 2.00E+07 3.46E+08 - - - 1.6517 0.9697 230117_WJC_METTL3_WT_vs_EV_F07.04356.04356.2 0.0591 12-May R.TATFQQR.F "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 850.4297 0.99 54657 4356 2 850.428672 426.2221 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.41 1533.7 - 208325 - - - -1.2276 - 0.946 0.219 - 120.9 1 2 0 -0.001 7 0 0 0 4.38E+06 4.44E+06 - - - 0.4823 0.8753 230117_WJC_METTL3_WT_vs_EV_F07.04359.04359.2 8.95 12-May R.NTTIPTK.K "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 11 773.4283 9.03 54658 4359 2 773.427263 387.7214 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.75 1534.1 - 2.06E+06 - - - -1.3653 - 1.08 0.036 - 67.1 1 2 0 -0.0011 7 0 0 0 5.83E+07 6.45E+06 - - - -0.4496 0.9428 230117_WJC_METTL3_WT_vs_EV_F07.04407.04407.2 2.98 12-Jun K.EQSIVEK.F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 831.4338 1244.25 54660 4407 2 831.432836 416.7242 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 1542.3 - 3.30E+07 - - - -1.157 - 1.307 0.016 - 248.3 1 2 0 -0.001 7 0 0 0 1.03E+09 8.25E+05 - - - 0.0072 0.9721 230117_WJC_METTL3_WT_vs_EV_F07.04473.04473.2 0.0416 18-Jul R.GGAGVGSMTK.L sp|P39019|RS19_HUMAN 1 863.4171 1.55 54666 4473 2 863.415203 432.7158 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1553.4 - 336575 - - - -2.1994 - 1.083 0.234 - 98.9 1 2 0 -0.0019 10 0 0 0 4.60E+06 2.98E+06 - - - 0.9913 0.9436 230117_WJC_METTL3_WT_vs_EV_F07.04482.04482.2 2.54 14-May K.VEEIAASK.C "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 845.4494 0.75 54667 4482 2 845.44837 423.732 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 4.53 1554.9 - 122492 - - - -1.2751 - 1.03 0.145 - 75.5 2 2 0 -0.0011 8 0 0 0 1.99E+06 2.66E+06 - - - 0.0663 0.9907 230117_WJC_METTL3_WT_vs_EV_F07.04495.04495.2 0.186 16-Apr K.VLENAEGAR.T "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 957.488 7.78 54669 4495 2 957.487082 479.7513 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.53 1556.9 - 363884 - - - -0.9159 - 1.083 0.282 - 48.7 2 2 0 -0.0009 9 0 0 0 7.40E+06 9.51E+05 - - - 1.2198 0.9802 230117_WJC_METTL3_WT_vs_EV_F07.04887.04887.2 2.44 14-Jun R.TSIEVGVK.G sp|Q03052|PO3F1_HUMAN 1 831.4702 999 54671 4887 2 831.471652 416.7424 "POU domain, class 3, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU3F1 PE=2 SV=3" 5.66 1627.7 - 2.32E+06 - - - 1.7668 - 1.106 0.112 - 100 2 2 0 0.0015 8 0 0 0 2.69E+09 0.00E+00 - - - 0.0372 0.9819 230117_WJC_METTL3_WT_vs_EV_F07.05108.05108.2 0.71 12-Jul K.LVEESVK[136.11].H "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 810.4578 0.12 54678 5108 2 810.456211 406.2362 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 1666.8 - 925246 - - - -2.0026 - 1.467 0.133 - 176.2 1 2 0 -0.0016 7 0 0 0 3.93E+06 3.18E+07 - - - 1.2371 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.05343.05343.2 0.0112 12-Jun K.SDSFAPK[136.11].T "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 758.369 0.001 54691 5343 2 758.370095 380.1918 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.55 1707.4 - 767095 - - - 1.4188 - 1.396 0.214 - 159.1 1 2 0 0.0011 7 0 0 0 0.00E+00 3.57E+07 - - - 1.6783 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.05469.05469.2 0.0017 14-Aug K.EHC[160.03]LVGVK.G sp|Q86U44|MTA70_HUMAN 1 940.48 21.16 54698 5469 2 940.480842 471.2473 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 1730 - 2.72E+06 - - - 0.8559 - 1.495 0.37 - 338.7 1 2 0 0.0008 8 0 0 0 8.87E+07 4.19E+06 - - - 2.9864 0.9896 230117_WJC_METTL3_WT_vs_EV_F07.05483.05483.2 2.51 12-Jul K.ITITNDK.G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 803.4389 12.93 54699 5483 2 803.440521 402.7267 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1732.6 - 801416 - - - 2.0387 - 1.428 0.048 - 194.5 1 2 0 0.0016 7 0 0 0 1.51E+08 1.17E+07 - - - 0.5239 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.05487.05487.2 3.93 12-Jul K.ITITNDK[136.11].G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 811.4531 12.94 54700 5487 2 811.453644 406.7338 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1733.3 - 100184 - - - 0.6914 - 1.368 0.207 - 144.2 1 2 0 0.0006 7 0 0 0 1.51E+08 1.17E+07 - - - 1.5626 0.9814 230117_WJC_METTL3_WT_vs_EV_F07.05534.05534.2 3.27 12-Jun K.FIDTTSK.F "sp|Q92901|RL3L_HUMAN,sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN" 3 810.4123 0.67 54701 5534 2 810.412856 406.2134 60S ribosomal protein L3-like OS=Homo sapiens OX=9606 GN=RPL3L PE=2 SV=3 5.84 1741.8 - 170528 - - - 0.6441 - 1.083 0.112 - 128.2 1 2 0 0.0005 7 0 0 0 7.39E+06 1.11E+07 - - - 0.1207 0.9868 230117_WJC_METTL3_WT_vs_EV_F07.05724.05724.2 5.89 12-Jul K.NADELVK.Q "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 5 787.4076 10.72 54708 5724 2 787.408485 394.7111 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.37 1775.7 - 894983 - - - 1.1455 - 1.122 0.119 - 173.2 1 2 0 0.0009 7 0 0 0 3.78E+07 3.52E+06 - - - 0.2844 0.9961 230117_WJC_METTL3_WT_vs_EV_F07.05853.05853.2 0.373 12-Jul K.LAEPYGK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 776.4069 1.44 54713 5853 2 776.408028 389.2107 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1798.6 - 475495 - - - 1.5108 - 1.293 0.177 - 208.7 1 2 0 0.0012 7 0 0 0 2.47E+07 1.71E+07 - - - 1.1622 0.9907 230117_WJC_METTL3_WT_vs_EV_F07.06010.06010.2 0.0557 18-Aug K.GSAITGPVAK[136.11].E "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 907.5218 1.77 54716 6010 2 907.520069 454.7682 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.75 1826 - 351921 - - - -1.9427 - 1.473 0.224 - 190.2 1 2 0 -0.0018 10 0 0 0 1.99E+07 1.13E+07 - - - 1.776 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.06190.06190.2 0.000976 16-Oct R.VTDALNATR.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 959.5036 2.16 54722 6190 2 959.504574 480.7591 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1859 - 578320 - - - 1.0057 - 1.968 0.401 - 407.1 1 2 0 0.001 9 0 0 0 9.39E+07 4.34E+07 - - - 3.9611 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.06195.06195.2 0.000598 16-Oct R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 2.16 54723 6195 2 969.513254 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1859.8 - 422952 - - - 1.4182 - 2.085 0.447 - 363 1 2 0 0.0014 9 0 0 0 9.39E+07 4.34E+07 - - - 4.4678 0.9443 230117_WJC_METTL3_WT_vs_EV_F07.06597.06597.2 2.09 14-Jun K.VISELNGK[136.11].N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 866.4953 1.52 54740 6597 2 866.496445 434.2549 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1931.2 - 147044 - - - 1.341 - 0.875 0.094 - 99 1 2 0 0.0012 8 0 0 0 2.26E+07 1.49E+07 - - - -0.6678 0.9221 230117_WJC_METTL3_WT_vs_EV_F07.06610.06610.2 0.956 14-May K.VISELNGK.N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 858.4811 1.33 54741 6610 2 858.483276 430.2478 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1933.5 - 387955 - - - 2.5545 - 0.824 0.118 - 77.4 1 2 0 0.0022 8 0 0 0 2.32E+07 1.74E+07 - - - -0.672 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.06890.06890.2 0.0008 24-Aug K.GPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1199.6146 999 54755 6890 2 1199.614515 600.8146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1981.8 - 87415.8 - - - -0.0842 - 1.888 0.43 - 134 1 2 0 -0.0001 13 0 0 0 1.01E+07 0.00E+00 - - - 3.848 0.9969 230117_WJC_METTL3_WT_vs_EV_F07.06914.06914.2 0.239 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 227.11 54758 6914 2 776.38346 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1985.9 - 676971 - - - 2.2631 - 1.434 0.18 - 181 1 2 0 0.0018 7 0 0 0 7.13E+09 3.14E+07 - - - 1.5121 0.983 230117_WJC_METTL3_WT_vs_EV_F07.06940.06940.2 3.81 14-Jul R.GTLDPVEK.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 857.4494 14.22 54759 6940 2 857.449722 429.732 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.37 1990.5 - 1.41E+06 - - - 0.3196 - 1.189 0.095 - 134 1 2 0 0.0003 8 0 0 0 1.24E+08 8.69E+06 - - - 0.2647 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.07029.07029.2 0.0824 16-Aug K.SAAMTLNER[166.11].F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1001.484 0.81 54765 7029 2 1001.485818 501.7493 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 2005.8 - 681881 - - - 1.8652 - 1.649 0.228 - 138.3 1 2 0 0.0019 9 0 0 0 2.32E+07 2.87E+07 - - - 2.1714 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.07058.07058.2 0.00177 16-Aug K.SAAMTLNER.F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 991.4757 0.81 54768 7058 2 991.475006 496.7451 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 2010.6 - 633928 - - - -0.6798 - 1.757 0.412 - 241.8 1 2 0 -0.0007 9 0 0 0 2.32E+07 2.87E+07 - - - 3.7144 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.07111.07111.2 0.123 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 0.9 54769 7111 2 776.381786 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2019.9 - 625673 - - - 0.1069 - 1.319 0.244 - 168.8 1 2 0 0.0001 7 0 0 0 1.10E+08 1.23E+08 - - - 1.7204 0.9946 230117_WJC_METTL3_WT_vs_EV_F07.07143.07143.2 0.0132 14-Aug K.GANPVEIR.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 854.461 1.8 54772 7143 2 854.460202 428.2378 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 2025.5 - 319192 - - - -0.9526 - 1.441 0.21 - 289 1 2 0 -0.0008 8 0 0 0 7.79E+07 4.34E+07 - - - 1.6936 0.8982 230117_WJC_METTL3_WT_vs_EV_F07.07161.07161.2 1.13 12-Jul R.IGVITNR[166.11].E sp|P62701|RS4X_HUMAN 1 781.4686 0.88 54774 7161 2 781.468713 391.7416 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2028.5 - 298167 - - - 0.1996 - 1.022 0 - 110.8 1 2 0 0.0002 7 0 0 0 2.33E+07 2.66E+07 - - - -0.8901 0.996 230117_WJC_METTL3_WT_vs_EV_F07.07197.07197.2 0.333 12-Aug R.IGVITNR.E sp|P62701|RS4X_HUMAN 1 771.4603 0.88 54780 7197 2 771.460916 386.7374 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2034.2 - 593214 - - - 0.8153 - 1.577 0.096 - 243.5 1 2 0 0.0006 7 0 0 0 2.33E+07 2.66E+07 - - - 1.1932 0.999 230117_WJC_METTL3_WT_vs_EV_F07.07198.07198.2 0.00665 14-Aug K.GANPVEIR[166.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 864.4693 1.8 54781 7198 2 864.469853 433.2419 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 2034.4 - 642970 - - - 0.6559 - 1.426 0.324 - 261 1 2 0 0.0006 8 0 0 0 7.79E+07 4.32E+07 - - - 2.5042 0.999 230117_WJC_METTL3_WT_vs_EV_F07.07230.07230.2 0.0363 14-Aug K.VGEVIVTK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.5208 2.04 54784 7230 2 851.52347 426.7677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2040 - 191288 - - - 3.172 - 1.965 0.3 - 158.6 1 2 0 0.0027 8 0 0 0 1.35E+08 6.63E+07 - - - 3.2932 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.07239.07239.2 0.00264 14-Sep K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 2.04 54786 7239 2 843.508741 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2041.4 - 770897 - - - 2.575 - 2.11 0.318 - 230.9 1 2 0 0.0022 8 0 0 0 1.35E+08 6.63E+07 - - - 3.641 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.07520.07520.2 0.444 16-Jun K.VTMQNLNDR.L "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 8 1089.5237 999 54804 7520 2 1089.524689 545.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.81 2090 - 237199 - - - 0.9151 - 1.244 0.252 - 94 1 2 0 0.001 9 0 0 0 8.98E+06 0.00E+00 - - - 1.5336 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.07533.07533.3 0.000124 Nov-44 R.TLVAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1299.763 0.46 54806 7533 3 1299.762719 434.2616 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2092.1 - 284000 - - - -0.1816 - 2.044 0.297 - 138.9 1 2 0 -0.0002 12 0 0 0 9.55E+06 2.10E+07 - - - 3.8328 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.07545.07545.3 0.00608 Oct-44 R.TLVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1281.7405 0.46 54808 7545 3 1281.740087 428.2541 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2093.9 - 389297 - - - -0.3105 - 1.692 0.352 - 117.4 1 2 0 -0.0004 12 0 0 0 9.52E+06 2.07E+07 - - - 3.9221 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.07662.07662.2 0.0251 14-Jun R.VLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 815.4753 0.93 54822 7662 2 815.474515 408.7449 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 2113.2 - 667092 - - - -0.9246 - 1.274 0.309 - 152.1 1 2 0 -0.0008 8 0 0 0 4.12E+07 4.44E+07 - - - 2.0534 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.07666.07666.2 0.00205 16-Jul R.VLNTNIDGR.R "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1000.5302 1.72 54823 7666 2 1000.529157 501.2724 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.81 2113.8 - 310946 - - - -1.0005 - 1.625 0.315 - 180.1 1 2 0 -0.001 9 0 0 0 3.57E+07 2.08E+07 - - - 2.7719 0.8465 230117_WJC_METTL3_WT_vs_EV_F07.07725.07725.2 7.27 12-Apr R.IFVNDDR.H "sp|Q12906|ILF3_HUMAN,tr|K7EM82|K7EM82_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7ENK6|K7ENK6_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7ERM6|K7ERM6_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 7 877.4294 0.87 54833 7725 2 877.429218 439.722 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 2123 - 90576.1 - - - -0.1858 - 1.05 0.003 - 53.1 4 2 0 -0.0002 7 0 0 0 2.67E+06 3.05E+06 - - - -1.0512 0.9499 230117_WJC_METTL3_WT_vs_EV_F07.07746.07746.2 25.5 12-Jun R.IPPVAVR[166.11].L "sp|Q14839|CHD4_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A0G2JM70|A0A0G2JM70_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|V9GYG6|V9GYG6_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 760.4835 0.001 54836 7746 2 760.483891 381.249 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 2126.4 - 455809 - - - 0.5418 - 1.072 0.06 - 124.8 3 2 0 0.0004 7 0 0 0 0.00E+00 7.56E+07 - - - -0.5088 0.9922 230117_WJC_METTL3_WT_vs_EV_F07.07770.07770.2 0.086 14-Aug R.FSELTAEK.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 923.46 6.68 54839 7770 2 923.463374 462.7373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2130.5 - 5.40E+06 - - - 3.6396 - 1.239 0.234 - 77.9 1 2 0 0.0034 8 0 0 0 4.82E+07 7.21E+06 - - - 1.4146 0.9677 230117_WJC_METTL3_WT_vs_EV_F07.07813.07813.2 6.75E-05 16-Nov Y.PDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 953.5546 999 54842 7813 2 953.554482 477.7846 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2137.8 - 690202 - - - -0.1049 - 2.185 0.419 - 420.7 1 1 0 -0.0001 9 0 0 0 3.94E+07 0.00E+00 - - - 4.397 0.9878 230117_WJC_METTL3_WT_vs_EV_F07.07839.07839.2 0.435 12-May R.EIAQDFK.T "sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 9 849.4232 0.75 54847 7839 2 849.423852 425.7189 Histone H3.1t OS=Homo sapiens OX=9606 GN=H3-4 PE=1 SV=3 4.37 2141.8 - 235254 - - - 0.7287 - 1.05 0.162 - 93.6 1 2 0 0.0006 7 0 0 0 1.33E+07 1.79E+07 - - - 0.3919 0.8821 230117_WJC_METTL3_WT_vs_EV_F07.07847.07847.2 0.0621 12-May D.VIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 784.4807 9.58 54849 7847 2 784.482029 393.2476 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 2143 - 404700 - - - 1.7081 - 1.224 0.301 - 128.5 1 1 0 0.0013 7 0 0 0 8.06E+07 8.41E+06 - - - 1.9042 0.9123 230117_WJC_METTL3_WT_vs_EV_F07.07862.07862.2 0.0164 14-Jul K.HVVFIAQR[166.11].R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 978.5639 2.32 54851 7862 2 978.571736 490.2892 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 9.76 2145.5 - 103605 - - - 8.0536 - 1.245 0.262 - 203.8 1 2 0 0.0079 8 0 0 0 1.09E+07 4.71E+06 - - - 1.6346 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.07929.07929.2 7.70E-05 16-Sep R.TLLEGEESR.M sp|P04264|K2C1_HUMAN 1 1032.5088 102.47 54858 7929 2 1032.509962 517.2617 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.25 2156.7 - 607046 - - - 1.17 - 1.903 0.493 - 283.4 1 2 0 0.0012 9 0 0 0 5.62E+07 5.48E+05 - - - 4.5434 0.9792 230117_WJC_METTL3_WT_vs_EV_F07.07930.07930.2 19.8 12-Jun R.IPPVAVR[166.11].L "sp|Q14839|CHD4_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A0G2JM70|A0A0G2JM70_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|V9GYG6|V9GYG6_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 760.4835 0.001 54859 7930 2 760.483567 381.249 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 2156.8 - 593833 - - - 0.1157 - 1.244 0.062 - 136 1 2 0 0.0001 7 0 0 0 0.00E+00 9.24E+07 - - - 0.1907 0.9772 230117_WJC_METTL3_WT_vs_EV_F07.08094.08094.2 0.117 12-May R.FC[160.03]ALEEK.C "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 895.411 0.28 54877 8094 2 895.409817 448.7128 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2184.1 - 181599 - - - -1.2698 - 1.042 0.208 - 76.2 1 2 0 -0.0011 7 0 0 0 1.04E+07 3.66E+07 - - - 0.7073 0.9842 230117_WJC_METTL3_WT_vs_EV_F07.08109.08109.2 3.53 14-Jul K.VC[160.03]NPIITK.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 943.5161 15.08 54880 8109 2 943.515978 472.7653 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.19 2186.3 - 246449 - - - -0.1166 - 1.223 0.129 - 150.8 2 2 0 -0.0001 8 0 0 0 1.15E+08 7.61E+06 - - - 0.4664 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.08172.08172.2 0.0273 16-Jul R.VPPPPPIAR[166.11].A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 952.5734 1.11 54887 8172 2 952.574664 477.294 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2196.8 - 595433 - - - 1.3721 - 1.213 0.258 - 84.4 1 2 0 0.0013 9 0 0 0 3.78E+07 3.41E+07 - - - 1.5048 0.9482 230117_WJC_METTL3_WT_vs_EV_F07.08179.08179.2 0.0266 14-May K.C[160.03]GEALGLK.Q "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 846.4269 0.57 54888 8179 2 846.427653 424.2207 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.99 2198 - 131881 - - - 0.8435 - 1.132 0 - 66.3 1 2 0 0.0007 8 0 0 0 1.76E+07 3.09E+07 - - - -0.5853 0.9064 230117_WJC_METTL3_WT_vs_EV_F07.08185.08185.2 0.0882 16-Aug R.PSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 969.5243 0.69 54889 8185 2 969.52654 485.7694 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.43 2198.9 - 172823 - - - 2.265 - 1.625 0.255 - 177.4 1 1 0 0.0022 9 0 0 0 1.14E+07 1.66E+07 - - - 2.3283 0.9812 230117_WJC_METTL3_WT_vs_EV_F07.08189.08189.2 7.85 12-Jul K.VLAAVYK.A "sp|P05062|ALDOB_HUMAN,sp|P04075|ALDOA_HUMAN,sp|P09972|ALDOC_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|A8MVZ9|A8MVZ9_HUMAN,tr|A0A3B3IS80|A0A3B3IS80_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|A0A087WXX2|A0A087WXX2_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 10 762.464 1.85 54891 8189 2 762.465173 382.2393 Fructose-bisphosphate aldolase B OS=Homo sapiens OX=9606 GN=ALDOB PE=1 SV=2 8.56 2199.5 - 512356 - - - 1.5699 - 1.207 0.056 - 122.7 1 2 0 0.0012 7 0 0 0 2.20E+08 1.19E+08 - - - 0.0504 0.9969 230117_WJC_METTL3_WT_vs_EV_F07.08196.08196.2 0.000816 14-Sep K.C[160.03]GEALGLK[136.11].Q "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 854.4411 0.56 54892 8196 2 854.442801 428.2278 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.99 2200.6 - 414854 - - - 1.9451 - 1.59 0.132 - 341.4 1 2 0 0.0017 8 0 0 0 1.78E+07 3.15E+07 - - - 1.414 0.8482 230117_WJC_METTL3_WT_vs_EV_F07.08199.08199.2 0.0408 16-Sep R.PSGLLAQER[166.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 979.5326 0.69 54893 8199 2 979.534109 490.7736 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.43 2201 - 279831 - - - 1.5262 - 1.664 0.15 - 244.5 1 1 0 0.0015 9 0 0 0 1.14E+07 1.66E+07 - - - 1.6216 0.9929 230117_WJC_METTL3_WT_vs_EV_F07.08201.08201.2 0.0791 12-May K.VLAAVYK[136.11].A "sp|P05062|ALDOB_HUMAN,sp|P04075|ALDOA_HUMAN,sp|P09972|ALDOC_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|A8MVZ9|A8MVZ9_HUMAN,tr|A0A3B3IS80|A0A3B3IS80_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|A0A087WXX2|A0A087WXX2_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 10 770.4782 1.85 54894 8201 2 770.479347 386.2464 Fructose-bisphosphate aldolase B OS=Homo sapiens OX=9606 GN=ALDOB PE=1 SV=2 8.56 2201.3 - 1.02E+06 - - - 1.5198 - 1.268 0.143 - 89.8 2 2 0 0.0012 7 0 0 0 2.20E+08 1.19E+08 - - - 0.7147 0.9947 230117_WJC_METTL3_WT_vs_EV_F07.08223.08223.2 0.0743 12-May R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 341.86 54898 8223 2 808.431738 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2204.7 - 1.04E+06 - - - -1.6476 - 1.284 0.311 - 63.6 1 2 0 -0.0013 7 0 0 0 1.61E+08 4.70E+05 - - - 2.1297 0.9781 230117_WJC_METTL3_WT_vs_EV_F07.08242.08242.2 5.46 14-May R.EFIQEPAK.N "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 5 960.4916 0.58 54900 8242 2 960.492887 481.2531 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.53 2207.9 - 138011 - - - 1.291 - 1.089 0.116 - 80.8 3 2 0 0.0012 8 0 0 0 3.94E+06 6.82E+06 - - - -0.0586 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.08250.08250.2 0.0779 18-Oct K.LLNTVEETTK.D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1146.6132 0.06 54901 8250 2 1146.6157 574.3139 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2209.3 - 874901 - - - 2.1638 - 1.493 0.268 - 252.6 1 2 0 0.0025 10 0 0 0 1.67E+06 2.69E+07 - - - 2.1384 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.08252.08252.2 0.00125 18-Oct K.LLNTVEETTK[136.11].D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1154.6274 0.06 54902 8252 2 1154.629781 578.321 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2209.5 - 692204 - - - 2.0457 - 2.177 0.403 - 285.4 1 2 0 0.0024 10 0 0 0 1.67E+06 2.69E+07 - - - 4.1883 0.953 230117_WJC_METTL3_WT_vs_EV_F07.08260.08260.2 0.00245 26-Jul C.TGGEVGATSALAPK.L sp|P30050|RL12_HUMAN 1 1257.6565 3.28 54904 8260 2 1257.6572 629.8355 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.66 2210.6 - 82211.5 - - - 0.5717 - 1.667 0.377 - 112.8 1 1 0 0.0007 14 0 0 0 2.87E+06 8.77E+05 - - - 3.1077 0.9116 230117_WJC_METTL3_WT_vs_EV_F07.08271.08271.2 4.09 12-Jun R.LLAVAER.Y sp|Q06609|RAD51_HUMAN 1 770.465 6.24 54905 8271 2 770.463624 386.2398 DNA repair protein RAD51 homolog 1 OS=Homo sapiens OX=9606 GN=RAD51 PE=1 SV=1 6 2212.5 - 780668 - - - -1.8353 - 1.338 0.032 - 126.4 3 2 0 -0.0014 7 0 0 0 2.92E+07 4.69E+06 - - - -0.0136 0.9932 230117_WJC_METTL3_WT_vs_EV_F07.08277.08277.2 0.326 14-Jul R.ILSGVVTK[136.11].M "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 823.5259 0.89 54909 8277 2 823.52661 412.7702 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 2213.3 - 535506 - - - 0.918 - 1.437 0.086 - 109.8 1 2 0 0.0008 8 0 0 0 4.05E+07 4.56E+07 - - - 0.7694 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.08298.08298.2 0.133 14-Aug R.IVVAAVAR[166.11].A "sp|Q7Z2T5|TRM1L_HUMAN,tr|X6RK96|X6RK96_HUMAN" 2 807.5206 1.64 54914 8298 2 807.521479 404.7676 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 9.75 2216.6 - 907439 - - - 1.0972 - 1.581 0.241 - 132.2 1 2 0 0.0009 8 0 0 0 6.31E+07 3.86E+07 - - - 2.2022 0.9783 230117_WJC_METTL3_WT_vs_EV_F07.08382.08382.2 0.456 16-May K.DLPEHAVLK[136.11].M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1028.5746 2.64 54927 8382 2 1028.576419 515.2946 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.32 2230.1 - 231186 - - - 1.7733 - 1.251 0.09 - 64.9 7 2 0 0.0018 9 0 0 0 5.73E+07 2.17E+07 - - - -0.0245 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.08408.08408.2 0.000303 18-Aug R.ASAVSELSPR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1015.5298 0.78 54931 8408 2 1015.531174 508.7722 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2234.3 - 134417 - - - 1.3294 - 1.648 0.232 - 134.5 1 2 0 0.0014 10 0 0 0 1.36E+07 1.75E+07 - - - 2.1486 0.9493 230117_WJC_METTL3_WT_vs_EV_F07.08427.08427.2 5.85 12-Jun R.LLPAEVK[136.11].A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 776.4887 1.33 54933 8427 2 776.488647 389.2516 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6 2237.5 - 2.43E+06 - - - -0.1211 - 1.081 0.053 - 124.9 1 2 0 -0.0001 7 0 0 0 3.03E+08 2.28E+08 - - - -0.3208 1 230117_WJC_METTL3_WT_vs_EV_F07.08470.08470.2 4.15E-06 20-Dec K.FAEALGSTEAK[136.11].A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1130.5699 0.33 54940 8470 2 1130.570104 566.2922 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2244.4 - 342433 - - - 0.1769 - 2.284 0.539 - 401.3 1 2 0 0.0002 11 0 0 0 6.13E+06 1.84E+07 - - - 5.2563 0.9776 230117_WJC_METTL3_WT_vs_EV_F07.08472.08472.2 2.14 12-Jun K.SEITELR.R "sp|P13645|K1C10_HUMAN,sp|Q8TDM6|DLG5_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 3 846.4447 7.59 54942 8472 2 846.443304 424.2296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2244.7 - 349719 - - - -1.6457 - 1.278 0.146 - 215.5 1 2 0 -0.0014 7 0 0 0 1.53E+07 2.02E+06 - - - 0.8962 0.9332 230117_WJC_METTL3_WT_vs_EV_F07.08529.08529.2 7.58 12-Jun K.VLALQAR[166.11].K "sp|Q96SB4|SRPK1_HUMAN,tr|C9JWF7|C9JWF7_HUMAN,tr|H3BLV9|H3BLV9_HUMAN,tr|F8WAV6|F8WAV6_HUMAN" 4 779.4893 1.51 54951 8529 2 779.488945 390.7519 SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2 9.72 2253.9 - 268172 - - - -0.4464 - 1.199 0 - 94.2 1 2 0 -0.0003 7 0 0 0 1.44E+07 9.55E+06 - - - -0.3841 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.08570.08570.2 0.0158 16-Aug R.ILQDSLGGR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 967.5326 0.32 54955 8570 2 967.532032 484.7736 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2260.8 - 173325 - - - -0.6015 - 1.706 0.298 - 195.5 1 2 0 -0.0006 9 0 0 0 7.49E+06 2.35E+07 - - - 2.7872 0.9895 230117_WJC_METTL3_WT_vs_EV_F07.08603.08603.2 0.433 14-Jul K.TFTMEGER[166.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 979.4309 1.34 54962 8603 2 979.431614 490.7227 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2265.9 - 292883 - - - 0.779 - 0.899 0.239 - 105.7 1 2 0 0.0008 8 0 0 0 5.53E+06 4.12E+06 - - - 0.4849 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.08607.08607.2 0.104 16-Aug R.ILQDSLGGR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 957.5243 0.32 54964 8607 2 957.524965 479.7694 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2266.4 - 181863 - - - 0.6485 - 1.456 0.256 - 166.7 1 2 0 0.0006 9 0 0 0 7.49E+06 2.35E+07 - - - 2.0185 0.978 230117_WJC_METTL3_WT_vs_EV_F07.08695.08695.2 0.989 12-Jul R.LLEQGIR.V "sp|P28340|DPOD1_HUMAN,sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 7 827.4865 1.5 54979 8695 2 827.487073 414.7505 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 6 2280.5 - 356383 - - - 0.69 - 1.329 0.008 - 148.5 1 2 0 0.0006 7 0 0 0 4.18E+07 2.79E+07 - - - 0.0011 0.9792 230117_WJC_METTL3_WT_vs_EV_F07.08763.08763.2 0.214 12-Aug K.NIQVVVR[166.11].C "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 836.5108 0.3 54996 8763 2 836.508226 419.2627 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 9.75 2290.6 - 906624 - - - -3.0257 - 1.315 0.236 - 278.5 1 2 0 -0.0025 7 0 0 0 2.37E+07 7.90E+07 - - - 1.651 0.9844 230117_WJC_METTL3_WT_vs_EV_F07.08833.08833.2 0.0498 12-Jul R.AMIIAER[166.11].Q "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 812.4454 1.65 55001 8833 2 812.443473 407.23 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.05 2302.2 - 1.04E+06 - - - -2.346 - 1.446 0.18 - 271.6 1 2 0 -0.0019 7 0 0 0 7.03E+07 4.26E+07 - - - 1.5384 0.977 230117_WJC_METTL3_WT_vs_EV_F07.08871.08871.2 0.911 12-Aug R.HLQLAIR.N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 849.5185 0.81 55010 8871 2 849.516747 425.7665 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2307.7 - 259789 - - - -2.0294 - 1.333 0.15 - 214.5 1 2 0 -0.0017 7 0 0 0 1.25E+08 1.55E+08 - - - 1.0591 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.08882.08882.2 0.261 12-Oct R.HLQLAIR[166.11].N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 859.5267 0.81 55012 8882 2 859.526595 430.7706 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2309.4 - 1.17E+06 - - - -0.1699 - 1.61 0.199 - 400.4 1 2 0 -0.0001 7 0 0 0 1.25E+08 1.55E+08 - - - 2.0197 0.995 230117_WJC_METTL3_WT_vs_EV_F07.08898.08898.2 0.261 16-Aug R.NIVEAAAVR[166.11].D "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 951.5377 0.93 55016 8898 2 951.537813 476.7761 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 6 2312 - 880647 - - - 0.1188 - 1.047 0.278 - 199.7 1 2 0 0.0001 9 0 0 0 2.27E+07 2.44E+07 - - - 1.2271 0.9827 230117_WJC_METTL3_WT_vs_EV_F07.08915.08915.2 1.15 14-May K.LVIEEAER.S sp|P50991|TCPD_HUMAN 1 957.5131 14.94 55017 8915 2 957.514928 479.7638 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.25 2315 - 224332 - - - 1.8976 - 1.113 0.106 - 62.3 1 2 0 0.0018 8 0 0 0 1.14E+07 7.63E+05 - - - 0.1462 0.9447 230117_WJC_METTL3_WT_vs_EV_F07.08924.08924.2 2.56 12-Jun K.LIETVVK[136.11].Q "sp|Q8TAG9|EXOC6_HUMAN,tr|E7EW84|E7EW84_HUMAN" 2 808.515 1.83 55019 8924 2 808.514119 405.2648 Exocyst complex component 6 OS=Homo sapiens OX=9606 GN=EXOC6 PE=1 SV=3 6 2316.4 - 315293 - - - -1.034 - 1.111 0.082 - 74.3 1 2 0 -0.0008 7 0 0 0 1.96E+07 1.07E+07 - - - -0.0201 0.9961 230117_WJC_METTL3_WT_vs_EV_F07.08925.08925.2 2.24 12-Jul K.LIVDSVK[136.11].E sp|O60216|RAD21_HUMAN 1 780.4837 5.49 55020 8925 2 780.483746 391.2491 Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2 5.84 2316.5 - 329282 - - - 0.1166 - 1.405 0.178 - 132.3 1 2 0 0.0001 7 0 0 0 1.11E+08 2.02E+07 - - - 1.4331 0.9809 230117_WJC_METTL3_WT_vs_EV_F07.08958.08958.2 0.33 12-Aug K.IIDAALR.A "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 770.465 2.25 55024 8958 2 770.464025 386.2398 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2321.9 - 3.52E+06 - - - -1.3148 - 1.305 0.132 - 207.7 1 2 0 -0.001 7 0 0 0 2.66E+09 1.18E+09 - - - 0.8591 0.9845 230117_WJC_METTL3_WT_vs_EV_F07.09116.09116.2 1.7 12-May R.LVGEIVR[166.11].R "sp|Q13232|NDK3_HUMAN,sp|Q15021|CND1_HUMAN,sp|Q3MIP1|IPIL2_HUMAN,tr|H3BRA8|H3BRA8_HUMAN,tr|H3BMQ7|H3BMQ7_HUMAN,tr|H3BPD9|H3BPD9_HUMAN,tr|E7EN77|E7EN77_HUMAN" 7 794.489 2.03 55048 9116 2 794.489474 398.2518 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6 2346.7 - 1.38E+06 - - - 0.6482 - 1.352 0.088 - 84.8 8 2 0 0.0005 7 0 0 0 1.04E+09 5.12E+08 - - - 0.243 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.09258.09258.2 0.0689 14-Jun R.GLDVEDVK.F "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 6 873.4444 0.96 55072 9258 2 873.444647 437.7295 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 2369.2 - 343868 - - - 0.3251 - 1.434 0.375 - 96.2 1 2 0 0.0003 8 0 0 0 1.60E+07 1.66E+07 - - - 2.8978 0.9716 230117_WJC_METTL3_WT_vs_EV_F07.09289.09289.2 2.14 14-May R.TTC[160.03]FQGVK.V "sp|Q86XD8|ZFAN4_HUMAN,tr|J3KPC0|J3KPC0_HUMAN" 2 939.4484 9.06 55078 9289 2 939.450385 470.7315 AN1-type zinc finger protein 4 OS=Homo sapiens OX=9606 GN=ZFAND4 PE=2 SV=2 7.89 2374 - 259778 - - - 2.1108 - 1.051 0.091 - 89.9 1 2 0 0.002 8 0 0 0 6.92E+07 7.64E+06 - - - -0.1375 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.09292.09292.2 0.0171 14-Jul K.VIPELNGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 868.5018 3 55079 9292 2 868.502061 435.2582 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2374.4 - 1.32E+06 - - - 0.2798 - 1.32 0.368 - 161.3 1 2 0 0.0002 8 0 0 0 1.21E+08 4.03E+07 - - - 2.5963 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.09296.09296.2 0.0289 16-Aug R.QTVAVGVIK.N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 913.5597 4.22 55081 9296 2 913.560731 457.7871 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2374.9 - 1.06E+06 - - - 1.1647 - 1.528 0.322 - 258.1 1 2 0 0.0011 9 0 0 0 7.99E+07 1.89E+07 - - - 2.6455 0.9948 230117_WJC_METTL3_WT_vs_EV_F07.09299.09299.2 0.234 16-Jun R.QTVAVGVIK[136.11].N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 921.5739 4.22 55082 9299 2 921.575438 461.7942 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2375.4 - 324951 - - - 1.7047 - 1.118 0.217 - 110.4 1 2 0 0.0016 9 0 0 0 7.99E+07 1.89E+07 - - - 0.966 0.9863 230117_WJC_METTL3_WT_vs_EV_F07.09315.09315.2 0.604 22-May R.TLIQNC[160.03]GASTIR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1332.682 0.91 55087 9315 2 1332.684129 667.3483 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 7.91 2377.7 - 57482.5 - - - 1.6095 - 1.035 0.196 - 45.1 5 2 0 0.0021 12 0 0 0 4.79E+06 5.24E+06 - - - 0.2663 0.9917 230117_WJC_METTL3_WT_vs_EV_F07.09345.09345.2 2.11 12-May K.VVPLYGR.G "sp|Q99942|RNF5_HUMAN,tr|A0A140TA09|A0A140TA09_HUMAN" 2 802.4701 2.47 55092 9345 2 802.471587 402.2423 E3 ubiquitin-protein ligase RNF5 OS=Homo sapiens OX=9606 GN=RNF5 PE=1 SV=1 8.72 2382.5 - 1.15E+06 - - - 1.8231 - 1.044 0.198 - 148.1 1 2 0 0.0015 7 0 0 0 1.02E+08 4.11E+07 - - - 0.6394 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.09346.09346.2 0.0129 14-Aug R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 0.98 55093 9346 2 898.52465 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 2382.6 - 575180 - - - 1.1508 - 1.455 0.371 - 214.4 1 2 0 0.001 8 0 0 0 6.53E+07 6.70E+07 - - - 2.9119 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.09361.09361.2 0.25 14-Aug R.LVGDVIQR[166.11].F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 908.5319 1.07 55097 9361 2 908.532769 455.2732 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 2384.9 - 1.23E+06 - - - 0.9719 - 1.48 0.201 - 204.1 1 2 0 0.0009 8 0 0 0 6.40E+07 5.99E+07 - - - 1.7077 0.9386 230117_WJC_METTL3_WT_vs_EV_F07.09412.09412.2 0.00774 14-Jul R.YPDGIISK.P sp|Q86U44|MTA70_HUMAN 1 891.4702 93.11 55113 9412 2 891.471265 446.7424 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2392.5 - 583410 - - - 1.2137 - 1.433 0.335 - 151.3 1 1 0 0.0011 8 0 0 0 5.08E+08 5.46E+06 - - - 2.6 0.9691 230117_WJC_METTL3_WT_vs_EV_F07.09416.09416.2 0.853 12-Jun R.IILPPEK.E sp|P49411|EFTU_HUMAN 1 808.5058 3.87 55115 9416 2 808.505825 405.2602 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6 2393 - 368467 - - - -0.0198 - 1.101 0.103 - 115.6 2 2 0 0 7 0 0 0 9.20E+07 2.38E+07 - - - -0.0278 0.9925 230117_WJC_METTL3_WT_vs_EV_F07.09469.09469.2 0.347 16-Jul K.TIAPALVSK[136.11].K "sp|P06733|ENOA_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y6I8|A0A2R8Y6I8_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 6 906.563 0.27 55124 9469 2 906.56289 454.2888 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 8.41 2401.4 - 212405 - - - -0.086 - 1.382 0.138 - 187.3 1 2 0 -0.0001 9 0 0 0 1.13E+07 4.23E+07 - - - 0.9962 0.9956 230117_WJC_METTL3_WT_vs_EV_F07.09480.09480.2 1.81 12-Jun K.LLEQALK.T sp|Q99543|DNJC2_HUMAN 1 813.496 1.43 55126 9480 2 813.495969 407.7553 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 6 2403.1 - 271409 - - - -0.043 - 1.5 0.144 - 90.9 1 2 0 0 7 0 0 0 1.52E+07 1.07E+07 - - - 1.3893 0.9863 230117_WJC_METTL3_WT_vs_EV_F07.09492.09492.2 4.5 16-Jul K.TIAPALVSK.K "sp|P06733|ENOA_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y6I8|A0A2R8Y6I8_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 6 898.5488 0.27 55131 9492 2 898.549271 450.2817 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 8.41 2404.6 - 265657 - - - 0.5598 - 1.187 0.11 - 127.2 1 2 0 0.0005 9 0 0 0 1.13E+07 4.22E+07 - - - 0.3493 0.9887 230117_WJC_METTL3_WT_vs_EV_F07.09508.09508.2 0.978 14-May R.LVTTGVLK[136.11].Q sp|P07305|H10_HUMAN 1 837.5415 1.02 55134 9508 2 837.542235 419.778 Histone H1.0 OS=Homo sapiens OX=9606 GN=H1-0 PE=1 SV=3 8.75 2407.1 - 454485 - - - 0.8728 - 1.203 0.148 - 46.6 4 2 0 0.0007 8 0 0 0 2.97E+07 2.91E+07 - - - 0.4224 0.9966 230117_WJC_METTL3_WT_vs_EV_F07.09510.09510.2 0.00334 12-Jun K.YGLNMC[160.03]R[166.11].Q "sp|P62273|RS29_HUMAN,tr|A0A2R8Y6P7|A0A2R8Y6P7_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 4 922.4029 1.2 55135 9510 2 922.402292 462.2087 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.22 2407.3 - 421164 - - - -0.619 - 1.091 0.351 - 98 1 2 0 -0.0006 7 0 0 0 1.26E+07 1.06E+07 - - - 1.9093 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.09519.09519.2 0.0607 14-Jul R.LVTTGVLK.Q sp|P07305|H10_HUMAN 1 829.5273 1.02 55137 9519 2 829.527646 415.7709 Histone H1.0 OS=Homo sapiens OX=9606 GN=H1-0 PE=1 SV=3 8.75 2408.7 - 666740 - - - 0.4123 - 1.696 0.241 - 172 1 2 0 0.0003 8 0 0 0 2.97E+07 2.92E+07 - - - 2.4142 0.9766 230117_WJC_METTL3_WT_vs_EV_F07.09539.09539.2 6.83 12-Jul R.LGLVDTR.Q sp|Q6P4I2|WDR73_HUMAN 1 772.4443 3.61 55140 9539 2 772.445246 387.2294 WD repeat-containing protein 73 OS=Homo sapiens OX=9606 GN=WDR73 PE=1 SV=1 5.84 2411.9 - 1.63E+06 - - - 1.2208 - 1.24 0.024 - 109.6 1 2 0 0.0009 7 0 0 0 1.66E+07 4.58E+06 - - - -0.1004 0.9845 230117_WJC_METTL3_WT_vs_EV_F07.09544.09544.2 0.0539 18-Jul R.GYSFTTTAER.E "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1131.5197 1.26 55141 9544 2 1131.516401 566.7671 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 2412.7 - 200936 - - - -2.874 - 1.293 0.281 - 176.5 1 2 0 -0.0033 10 0 0 0 9.53E+06 7.55E+06 - - - 1.8327 0.9926 230117_WJC_METTL3_WT_vs_EV_F07.09545.09545.2 0.0192 18-Aug K.FADLSEAANR.N "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1092.52 1.55 55142 9545 2 1092.516372 547.2673 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 2412.8 - 169649 - - - -3.3089 - 1.669 0.33 - 200.8 1 2 0 -0.0036 10 0 0 0 3.42E+07 2.20E+07 - - - 2.907 0.96 230117_WJC_METTL3_WT_vs_EV_F07.09585.09585.2 0.00682 22-Sep F.SGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1155.5408 109.21 55155 9585 2 1155.541806 578.7777 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.55 2418.5 - 188172 - - - 0.8862 - 1.796 0.357 - 191.5 1 1 0 0.001 12 0 0 0 9.09E+06 8.33E+04 - - - 3.2182 0.9532 230117_WJC_METTL3_WT_vs_EV_F07.09646.09646.2 1.45 12-May K.LEPVPLK.G "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN" 2 794.4902 2.32 55168 9646 2 794.489829 398.2524 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6 2427.8 - 586265 - - - -0.4556 - 1.074 0.08 - 93.1 1 2 0 -0.0004 7 0 0 0 7.21E+07 3.12E+07 - - - -0.142 0.9962 230117_WJC_METTL3_WT_vs_EV_F07.09654.09654.2 3.94 14-Jul R.LLTGPVVR.G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 853.5385 2.39 55170 9654 2 853.538629 427.7765 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2429 - 448184 - - - 0.1066 - 1.485 0.166 - 125.1 1 2 0 0.0001 8 0 0 0 4.98E+07 2.08E+07 - - - 1.4596 0.9799 230117_WJC_METTL3_WT_vs_EV_F07.09660.09660.2 0.521 12-Jun K.LEPVPLK[136.11].G "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN" 2 802.5044 2.33 55171 9660 2 802.504439 402.2595 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6 2429.9 - 789279 - - - 0.0598 - 1.274 0.094 - 159.1 4 2 0 0 7 0 0 0 7.26E+07 3.12E+07 - - - 0.2336 0.9931 230117_WJC_METTL3_WT_vs_EV_F07.09681.09681.2 0.538 12-Jun R.ILVDVEK.V sp|P11216|PYGB_HUMAN 1 814.48 0.23 55176 9681 2 814.480073 408.2473 "Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB PE=1 SV=5" 4.37 2433 - 562624 - - - 0.0651 - 1.416 0.116 - 105.3 1 2 0 0.0001 7 0 0 0 1.46E+07 6.22E+07 - - - 0.9999 0.9998 230117_WJC_METTL3_WT_vs_EV_F07.09684.09684.3 0.00913 15/40 R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 2.24 55177 9684 3 1240.608208 414.5431 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2433.4 - 324897 - - - 0.5143 - 1.84 0.399 - 204.8 1 2 0 0.0006 11 0 0 0 2.93E+07 1.31E+07 - - - 4.7205 0.9717 230117_WJC_METTL3_WT_vs_EV_F07.09691.09691.2 2.78 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 92 55179 9691 2 841.502821 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 2434.4 - 6.45E+06 - - - 0.795 - 1.31 0.013 - 195.7 2 2 0 0.0007 8 0 0 0 9.42E+08 1.02E+07 - - - -0.1833 0.9961 230117_WJC_METTL3_WT_vs_EV_F07.09722.09722.2 0.266 12-Jun K.LVAQLYK.L "sp|O75390|CISY_HUMAN,tr|H0YIC4|H0YIC4_HUMAN,tr|B4DJV2|B4DJV2_HUMAN,tr|A0A0C4DGI3|A0A0C4DGI3_HUMAN" 4 833.5011 1.72 55187 9722 2 833.501593 417.7578 "Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2" 8.59 2438.9 - 323557 - - - 0.6035 - 1.288 0.193 - 108.7 1 2 0 0.0005 7 0 0 0 4.18E+07 2.43E+07 - - - 1.2683 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.09733.09733.2 0.703 12-Jul R.VLSSLVR.D sp|Q969H6|POP5_HUMAN 1 772.4807 1.86 55189 9733 2 772.481665 387.2476 Ribonuclease P\MRP protein subunit POP5 OS=Homo sapiens OX=9606 GN=POP5 PE=1 SV=1 9.72 2440.7 - 488981 - - - 1.2635 - 1.39 0.28 - 212.3 1 2 0 0.001 7 0 0 0 5.81E+07 3.13E+07 - - - 2.1522 0.9738 230117_WJC_METTL3_WT_vs_EV_F07.09755.09755.2 1.86 12-Jul R.LGPETFR[166.11].Q sp|P57086|SCND1_HUMAN 1 828.4369 1.77 55195 9755 2 828.437336 415.2257 SCAN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCAND1 PE=1 SV=1 6 2443.9 - 126899 - - - 0.4985 - 1.224 0.033 - 110.9 1 2 0 0.0004 7 0 0 0 4.88E+07 2.75E+07 - - - -0.0749 0.9962 230117_WJC_METTL3_WT_vs_EV_F07.09767.09767.2 0.0557 16-Jul K.IVVVTAGVR[166.11].Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 922.5839 0.85 55198 9767 2 922.584401 462.2992 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2445.8 - 564238 - - - 0.5192 - 1.446 0.161 - 140.8 1 2 0 0.0005 9 0 0 0 1.49E+08 1.76E+08 - - - 1.297 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.09774.09774.2 0.344 12-Jul K.LEATMLR.L "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 832.4477 1.09 55201 9774 2 832.448615 417.2311 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6 2446.8 - 603936 - - - 1.1304 - 1.468 0.133 - 163.1 1 2 0 0.0009 7 0 0 0 2.66E+07 2.45E+07 - - - 1.2395 1 230117_WJC_METTL3_WT_vs_EV_F07.09778.09778.2 0.00117 22-Dec R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 999 55203 9778 2 1380.642701 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2447.3 - 202383 - - - 1.3117 - 2.364 0.456 - 444.5 1 2 0 0.0018 12 0 0 0 9.17E+06 0.00E+00 - - - 4.6722 0.8863 230117_WJC_METTL3_WT_vs_EV_F07.09781.09781.2 0.379 12-Aug N.LNTLIQR[166.11].S "sp|P20036|DPA1_HUMAN,sp|Q00839|HNRPU_HUMAN,sp|Q8IUG5|MY18B_HUMAN,tr|A0A140T914|A0A140T914_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|F5H6I8|F5H6I8_HUMAN,tr|A0A140T9R4|A0A140T9R4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A140T9D6|A0A140T9D6_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A140T9Y9|A0A140T9Y9_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A140T9H1|A0A140T9H1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A140T9U4|A0A140T9U4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A140T9F8|A0A140T9F8_HUMAN,tr|J3KQ99|J3KQ99_HUMAN" 24 866.5213 0.57 55204 9781 2 866.521778 434.2679 "HLA class II histocompatibility antigen, DP alpha 1 chain OS=Homo sapiens OX=9606 GN=HLA-DPA1 PE=1 SV=1" 9.75 2447.7 - 3.44E+06 - - - 0.5274 - 1.907 0.131 - 283.4 1 1 0 0.0005 7 0 0 0 1.14E+08 1.99E+08 - - - 2.0538 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.09786.09786.2 0.00594 16-Oct K.IVVVTAGVR.Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 912.5757 0.88 55206 9786 2 912.575719 457.2951 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2448.4 - 1.43E+06 - - - 0.0734 - 1.823 0.342 - 410.5 1 2 0 0.0001 9 0 0 0 1.55E+08 1.76E+08 - - - 3.3042 0.8626 230117_WJC_METTL3_WT_vs_EV_F07.09789.09789.2 0.364 12-Aug N.LNTLIQR.S "sp|P20036|DPA1_HUMAN,sp|Q00839|HNRPU_HUMAN,sp|Q8IUG5|MY18B_HUMAN,tr|A0A140T914|A0A140T914_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|F5H6I8|F5H6I8_HUMAN,tr|A0A140T9R4|A0A140T9R4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A140T9D6|A0A140T9D6_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A140T9Y9|A0A140T9Y9_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A140T9H1|A0A140T9H1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A140T9U4|A0A140T9U4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A140T9F8|A0A140T9F8_HUMAN,tr|J3KQ99|J3KQ99_HUMAN" 24 856.5131 0.35 55207 9789 2 856.513252 429.2638 "HLA class II histocompatibility antigen, DP alpha 1 chain OS=Homo sapiens OX=9606 GN=HLA-DPA1 PE=1 SV=1" 9.75 2448.8 - 3.12E+06 - - - 0.2347 - 1.828 0.137 - 282.7 1 1 0 0.0002 7 0 0 0 1.13E+08 3.20E+08 - - - 1.9642 0.965 230117_WJC_METTL3_WT_vs_EV_F07.09797.09797.2 10.1 12-Jun K.ILLSPER[166.11].V "sp|P24928|RPB1_HUMAN,tr|H3BVE3|H3BVE3_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 3 836.4995 0.99 55210 9797 2 836.500432 419.257 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 6 2449.9 - 525132 - - - 1.0867 - 1.13 0.029 - 94.7 1 2 0 0.0009 7 0 0 0 1.27E+08 1.29E+08 - - - -0.3578 0.9924 230117_WJC_METTL3_WT_vs_EV_F07.09801.09801.2 0.0987 18-Aug K.IGAVEEELNR.V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1128.5775 0.7 55212 9801 2 1128.583206 565.296 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.25 2450.4 - 246064 - - - 5.0542 - 1.711 0.242 - 141 1 2 0 0.0057 10 0 0 0 7.67E+06 1.09E+07 - - - 2.3258 0.999 230117_WJC_METTL3_WT_vs_EV_F07.09802.09802.2 0.0496 18-Oct K.IGAVEEELNR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1138.5858 0.84 55213 9802 2 1138.585855 570.3002 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.25 2450.6 - 212661 - - - 0.0729 - 1.934 0.251 - 339.5 1 2 0 0.0001 10 0 0 0 7.72E+06 9.24E+06 - - - 2.736 0.9515 230117_WJC_METTL3_WT_vs_EV_F07.09820.09820.2 0.345 12-Aug R.IPGIYGR.L "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 774.4388 1.16 55218 9820 2 774.436158 388.2267 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.75 2453.1 - 239549 - - - -3.4425 - 1.387 0.145 - 183.3 1 2 0 -0.0027 7 0 0 0 1.71E+08 1.47E+08 - - - 1.1477 0.8686 230117_WJC_METTL3_WT_vs_EV_F07.09831.09831.2 0.256 12-Jun N.VDEFVK[136.11]R.L sp|Q9NVH2|INT7_HUMAN 1 899.4956 - 55220 9831 2 899.497075 450.7551 Integrator complex subunit 7 OS=Homo sapiens OX=9606 GN=INTS7 PE=1 SV=1 6.04 2454.8 - 487182 - - - 1.6209 - 1.402 0.226 - 88.6 1 1 0 0.0015 7 0 0 0 - - - - - 1.7804 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.09886.09886.2 0.0837 12-Jul R.MIVGTLK.G "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 760.4517 2.75 55229 9886 2 760.452294 381.2331 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 8.5 2463.6 - 848306 - - - 0.7851 - 1.29 0.222 - 210.5 1 2 0 0.0006 7 0 0 0 4.26E+08 1.55E+08 - - - 1.4874 0.9537 230117_WJC_METTL3_WT_vs_EV_F07.09891.09891.2 3.4 12-Jun R.MIVGTLK[136.11].G "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 768.4659 2.78 55230 9891 2 768.465925 385.2402 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 8.5 2464.3 - 694299 - - - 0.0364 - 1.036 0.072 - 118 1 2 0 0 7 0 0 0 4.25E+08 1.53E+08 - - - -0.3152 0.9821 230117_WJC_METTL3_WT_vs_EV_F07.09906.09906.2 1.58 12-Jun R.ILLEAAR[166.11].L "sp|P49189|AL9A1_HUMAN,sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 3 794.489 2.13 55233 9906 2 794.488319 398.2518 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3 6 2466.6 - 581355 - - - -0.8055 - 1.382 0.082 - 127.1 1 2 0 -0.0006 7 0 0 0 7.99E+07 3.75E+07 - - - 0.6716 0.978 230117_WJC_METTL3_WT_vs_EV_F07.09923.09923.2 4.18 12-Jun R.ILLEAAR.L "sp|P49189|AL9A1_HUMAN,sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 3 784.4807 2.14 55236 9923 2 784.480451 393.2476 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3 6 2469.2 - 1.68E+06 - - - -0.3034 - 1.242 0.097 - 92.2 2 2 0 -0.0002 7 0 0 0 8.20E+07 3.84E+07 - - - 0.3096 0.8804 230117_WJC_METTL3_WT_vs_EV_F07.09950.09950.2 0.0431 12-Aug G.IIEPSLR.Q "sp|P62987|RL40_HUMAN,tr|M0R1A4|M0R1A4_HUMAN,tr|M0QZ32|M0QZ32_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|M0R1M6|M0R1M6_HUMAN" 5 826.4913 1.23 55242 9950 2 826.492093 414.2529 Ubiquitin-60S ribosomal protein L40 OS=Homo sapiens OX=9606 GN=UBA52 PE=1 SV=2 6 2473.3 - 3.05E+06 - - - 1.0163 - 1.765 0.141 - 224.9 1 1 0 0.0008 7 0 0 0 1.07E+09 8.71E+08 - - - 1.8824 1 230117_WJC_METTL3_WT_vs_EV_F07.10031.10031.2 3.29E-08 22-Dec R.AQVQEFC[160.03]DYGTK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1444.6293 12.64 55256 10031 2 1444.631644 723.3219 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2486.1 - 371877 - - - 1.6364 - 2.448 0.673 - 485.9 1 2 0 0.0024 12 0 0 0 3.08E+07 2.44E+06 - - - 6.3666 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.10037.10037.2 0.037 14-Sep R.VMGLVPAK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 821.4924 1.65 55257 10037 2 821.493556 411.7535 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.72 2487.1 - 729826 - - - 1.3512 - 1.305 0.247 - 212 1 2 0 0.0011 8 0 0 0 4.74E+07 2.88E+07 - - - 1.6678 0.9908 230117_WJC_METTL3_WT_vs_EV_F07.10049.10049.2 0.0386 12-Jun R.LMDVMAK.E sp|Q12874|SF3A3_HUMAN 1 806.403 3.34 55261 10049 2 806.401397 404.2088 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2488.7 - 504762 - - - -2.0275 - 1.275 0.273 - 100.7 1 2 0 -0.0016 7 0 0 0 1.52E+08 4.54E+07 - - - 1.8267 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.10059.10059.2 3.48E-06 22-Jul R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 12.63 55265 10059 2 1452.64547 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2490 - 53330.4 - - - 1.3699 - 1.263 0.551 - 131.5 1 2 0 0.002 12 0 0 0 3.08E+07 2.44E+06 - - - 3.7244 0.8746 230117_WJC_METTL3_WT_vs_EV_F07.10061.10061.2 6.67 16-Jun R.GPLVNASLR[166.11].A "sp|O14744|ANM5_HUMAN,tr|H0YJ77|H0YJ77_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 3 935.5428 0.47 55266 10061 2 935.543721 468.7787 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 9.75 2490.2 - 319513 - - - 1.0005 - 0.956 0.057 - 71.2 15 2 0 0.0009 9 0 0 0 3.51E+06 7.42E+06 - - - -1.1938 0.9961 230117_WJC_METTL3_WT_vs_EV_F07.10073.10073.2 0.596 12-May R.LMDVMAK[136.11].E sp|Q12874|SF3A3_HUMAN 1 814.4172 3.32 55268 10073 2 814.417435 408.2159 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2492.2 - 952846 - - - 0.2493 - 1.078 0.312 - 60.1 3 2 0 0.0002 7 0 0 0 1.51E+08 4.53E+07 - - - 1.3702 0.9949 230117_WJC_METTL3_WT_vs_EV_F07.10123.10123.2 0.755 14-Sep R.IIAEALTR.V "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 5 885.5284 0.97 55276 10123 2 885.529635 443.7715 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 2500.5 - 579499 - - - 1.4319 - 1.368 0.131 - 219.9 1 2 0 0.0013 8 0 0 0 6.28E+07 6.50E+07 - - - 0.9532 0.9873 230117_WJC_METTL3_WT_vs_EV_F07.10128.10128.2 3.42 14-Jun R.IIAEALTR[166.11].V "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 5 895.5366 0.97 55277 10128 2 895.537127 448.7756 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 2501.2 - 859217 - - - 0.5472 - 1.138 0.132 - 86.6 1 2 0 0.0005 8 0 0 0 6.28E+07 6.50E+07 - - - 0.4057 0.972 230117_WJC_METTL3_WT_vs_EV_F07.10148.10148.2 5.42 12-Jul K.LLNVGVR.E sp|O60512|B4GT3_HUMAN 1 769.481 0.79 55281 10148 2 769.481725 385.7478 "Beta-1,4-galactosyltransferase 3 OS=Homo sapiens OX=9606 GN=B4GALT3 PE=1 SV=2" 9.75 2504.4 - 1.24E+06 - - - 0.9123 - 1.271 0.019 - 161.2 2 2 0 0.0007 7 0 0 0 6.19E+07 7.80E+07 - - - -0.1935 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.10165.10165.2 0.242 16-Aug K.VELQELNDR.F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1114.5619 4.65 55286 10165 2 1114.565287 558.2882 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.14 2506.9 - 263264 - - - 3.0819 - 1.727 0.279 - 253 1 2 0 0.0034 9 0 0 0 3.59E+07 7.73E+06 - - - 2.6813 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.10171.10171.2 1.41 12-Jul K.EGIVALR[166.11].R sp|P40227|TCPZ_HUMAN 1 766.4577 0.56 55287 10171 2 766.457857 384.2361 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 6.1 2507.9 - 840056 - - - 0.2596 - 1.565 0.158 - 214.5 1 2 0 0.0002 7 0 0 0 6.64E+07 1.18E+08 - - - 1.6271 0.9806 230117_WJC_METTL3_WT_vs_EV_F07.10185.10185.2 0.344 12-Jul R.VLYSLAK[136.11].K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 800.4887 1.37 55289 10185 2 800.48805 401.2516 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.56 2510.1 - 750678 - - - -0.8632 - 1.227 0.147 - 155.7 2 2 0 -0.0007 7 0 0 0 7.68E+07 5.59E+07 - - - 0.6403 0.9878 230117_WJC_METTL3_WT_vs_EV_F07.10187.10187.2 0.979 12-Jun R.VLYSLAK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 792.4745 1.38 55290 10187 2 792.473641 397.2445 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.56 2510.5 - 715188 - - - -1.1357 - 1.427 0.128 - 117.9 1 2 0 -0.0009 7 0 0 0 7.77E+07 5.62E+07 - - - 1.1128 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.10263.10263.2 0.012 12-Jul R.LYTVVPR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 856.5046 1.39 55307 10263 2 856.506237 429.2596 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 2521.8 - 2.47E+06 - - - 1.9007 - 1.425 0.378 - 200.2 1 2 0 0.0016 7 0 0 0 1.86E+08 1.34E+08 - - - 2.9546 0.9935 230117_WJC_METTL3_WT_vs_EV_F07.10270.10270.2 0.021 14-Aug K.IPAMTIAK[136.11].N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.503 2.14 55310 10270 2 851.501944 426.7588 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2522.8 - 784168 - - - -1.2519 - 1.527 0.186 - 159.1 1 2 0 -0.0011 8 0 0 0 2.57E+09 1.20E+09 - - - 1.6911 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.10281.10281.2 0.00712 14-Sep K.IPAMTIAK.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.4888 2.14 55313 10281 2 843.488085 422.7517 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2524.3 - 4.06E+06 - - - -0.8595 - 1.802 0.27 - 246 1 2 0 -0.0007 8 0 0 0 2.57E+09 1.20E+09 - - - 2.8111 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.10309.10309.2 0.000318 16-Aug R.VLPVYGGPK.G "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 928.5382 2.05 55320 10309 2 928.537638 465.2764 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 8.56 2528.3 - 277816 - - - -0.6085 - 1.508 0.406 - 155 1 2 0 -0.0006 9 0 0 0 1.67E+07 8.17E+06 - - - 3.228 0.9944 230117_WJC_METTL3_WT_vs_EV_F07.10397.10397.2 0.0161 16-Oct K.LSDGVAVLK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 908.5422 2.5 55329 10397 2 908.53926 455.2784 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2542.4 - 2.70E+06 - - - -3.2723 - 1.906 0.317 - 196.6 1 2 0 -0.003 9 0 0 0 2.94E+08 1.18E+08 - - - 3.2475 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.10408.10408.2 0.129 16-Aug K.LSDGVAVLK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 900.528 2.5 55331 10408 2 900.528548 451.2713 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2544 - 7.13E+06 - - - 0.5719 - 1.485 0.288 - 137.5 1 2 0 0.0005 9 0 0 0 2.94E+08 1.18E+08 - - - 2.312 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.10457.10457.2 0.00241 12-Jul R.LVDMMER.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 892.4147 1.16 55334 10457 2 892.413767 447.2146 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 2552.2 - 1.32E+06 - - - -0.9995 - 1.165 0.462 - 163.2 1 2 0 -0.0009 7 0 0 0 2.29E+08 1.96E+08 - - - 2.937 0.9777 230117_WJC_METTL3_WT_vs_EV_F07.10463.10463.2 0.815 12-Jul R.LLAALER[166.11].R sp|Q96A98|TIP39_HUMAN 1 794.489 1.31 55336 10463 2 794.487705 398.2518 Tuberoinfundibular peptide of 39 residues OS=Homo sapiens OX=9606 GN=PTH2 PE=1 SV=1 6 2552.9 - 8.78E+06 - - - -1.5784 - 1.61 0.072 - 155.7 3 2 0 -0.0013 7 0 0 0 1.69E+09 1.29E+09 - - - 0.8682 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.10467.10467.2 0.0885 12-Jul R.LVDMMER[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 902.4229 1.16 55337 10467 2 902.424213 452.2187 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 2553.5 - 4.68E+06 - - - 1.4228 - 1.189 0.338 - 149.1 1 2 0 0.0013 7 0 0 0 2.28E+08 1.96E+08 - - - 2.0856 0.9311 230117_WJC_METTL3_WT_vs_EV_F07.10482.10482.2 0.0173 14-Sep K.PSPLLVGR.E "sp|Q13283|G3BP1_HUMAN,sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2R0|A0A7I2V2R0_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RGJ4|D6RGJ4_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|D6R9A4|D6R9A4_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|E5RI46|E5RI46_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 25 837.5072 1.33 55340 10482 2 837.507716 419.7609 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 10.18 2555.7 - 1.22E+06 - - - 0.5707 - 1.441 0.334 - 224.1 1 1 0 0.0005 8 0 0 0 1.61E+08 1.21E+08 - - - 2.6096 0.9926 230117_WJC_METTL3_WT_vs_EV_F07.10530.10530.2 0.954 12-Jul K.FIGELGK.L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 762.4276 2.32 55345 10530 2 762.426206 382.2211 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2563.5 - 2.75E+06 - - - -1.8153 - 1.485 0.218 - 174.7 1 2 0 -0.0014 7 0 0 0 3.28E+08 1.41E+08 - - - 1.9036 0.9919 230117_WJC_METTL3_WT_vs_EV_F07.10539.10539.2 0.3 14-Aug R.VVLLAEGR.L sp|O43865|SAHH2_HUMAN 1 855.5178 2.84 55347 10539 2 855.515233 428.7662 S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1 PE=1 SV=2 5.97 2564.8 - 979503 - - - -3.0029 - 1.498 0.313 - 214.6 1 2 0 -0.0026 8 0 0 0 5.49E+07 1.94E+07 - - - 2.5709 0.886 230117_WJC_METTL3_WT_vs_EV_F07.10541.10541.2 0.38 12-Jun K.FIGELGK[136.11].L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 770.4418 2.27 55348 10541 2 770.437412 386.2282 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2565 - 707719 - - - -5.6825 - 1.243 0.244 - 148.5 1 2 0 -0.0044 7 0 0 0 3.20E+08 1.41E+08 - - - 1.5311 0.9949 230117_WJC_METTL3_WT_vs_EV_F07.10580.10580.2 0.0162 14-Jul R.LGPLQVAR.V sp|P38117|ETFB_HUMAN 1 852.5181 3.33 55354 10580 2 852.516086 427.2663 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 9.75 2571 - 3.64E+06 - - - -2.4058 - 1.598 0.301 - 207.8 1 2 0 -0.0021 8 0 0 0 3.22E+08 9.68E+07 - - - 2.6773 0.8459 230117_WJC_METTL3_WT_vs_EV_F07.10589.10589.2 0.18 12-Jun R.VVDLMAH.M "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 783.3949 - 55355 10589 2 783.393978 392.7047 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.08 2572.4 - 8.76E+06 - - - -1.1897 - 1.345 0.369 - 127.4 1 1 0 -0.0009 7 0 0 0 - - - - - 2.7053 0.9335 230117_WJC_METTL3_WT_vs_EV_F07.10597.10597.2 2.15 12-Jun R.LVNIVPK[136.11].K "sp|Q8NEY8|PPHLN_HUMAN,tr|F8VRK2|F8VRK2_HUMAN,tr|F8VWU8|F8VWU8_HUMAN,tr|F8VXV7|F8VXV7_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8VPY7|F8VPY7_HUMAN" 6 789.5204 0.87 55358 10597 2 789.5192 395.7675 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 8.75 2573.5 - 3.96E+06 - - - -1.4882 - 1.421 0.003 - 135.1 2 2 0 -0.0012 7 0 0 0 2.41E+08 2.78E+08 - - - 0.0416 0.9839 230117_WJC_METTL3_WT_vs_EV_F07.10606.10606.2 1.92 12-Jun K.AIFAGYK.R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 768.417 0.78 55360 10606 2 768.416524 385.2158 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2574.8 - 2.07E+06 - - - -0.6533 - 1.136 0.167 - 123 1 2 0 -0.0005 7 0 0 0 3.15E+08 4.03E+08 - - - 0.6783 0.9927 230117_WJC_METTL3_WT_vs_EV_F07.10614.10614.2 0.207 12-Jun K.AIFAGYK[136.11].R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 776.4312 0.78 55362 10614 2 776.431075 389.2229 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2576 - 4.80E+06 - - - -0.1945 - 1.142 0.217 - 150.3 1 2 0 -0.0002 7 0 0 0 3.15E+08 4.03E+08 - - - 1.0644 0.9969 230117_WJC_METTL3_WT_vs_EV_F07.10645.10645.2 0.158 12-Jul R.LPPDVLR.W sp|P78527|PRKDC_HUMAN 1 808.4807 19.2 55366 10645 2 808.481907 405.2476 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2580.9 - 1.73E+06 - - - 1.5065 - 1.343 0.185 - 171.2 1 2 0 0.0012 7 0 0 0 1.80E+09 9.36E+07 - - - 1.3415 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.10663.10663.2 0.000634 16-Oct R.QEYEQLIAK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1120.5764 0.61 55371 10663 2 1120.579874 561.2955 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.53 2583.4 - 347067 - - - 3.0645 - 1.888 0.446 - 385.2 1 2 0 0.0034 9 0 0 0 1.94E+07 3.17E+07 - - - 4.1727 0.8772 230117_WJC_METTL3_WT_vs_EV_F07.10672.10672.2 4.82 12-Mar K.VLLAEYK.N sp|Q16513|PKN2_HUMAN 1 834.4851 0 55375 10672 2 834.485589 418.2498 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 5.97 2584.5 - 1.83E+06 - - - 0.58 - 0.899 0.092 - 32.7 13 2 0 0.0005 7 0 0 0 7.72E+07 2.54E+10 - - - -1.1146 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.10683.10683.2 0.372 14-Aug K.LLEATELK.G "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 915.5277 1.11 55380 10683 2 915.527076 458.7711 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 2586.1 - 1.05E+06 - - - -0.6794 - 1.444 0.294 - 177.7 1 2 0 -0.0006 8 0 0 0 5.22E+07 4.72E+07 - - - 2.3204 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.10685.10685.2 0.292 14-Jul K.YVPLADVK[136.11].S "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 911.5208 1.03 55381 10685 2 911.521196 456.7677 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.83 2586.3 - 1.16E+06 - - - 0.4684 - 1.205 0.263 - 195 1 2 0 0.0004 8 0 0 0 9.60E+07 9.30E+07 - - - 1.5458 0.9926 230117_WJC_METTL3_WT_vs_EV_F07.10686.10686.2 0.809 12-Jul R.VLISSLK.D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 758.4902 0.8 55382 10686 2 758.491067 380.2524 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2586.5 - 773445 - - - 1.1549 - 1.352 0.094 - 135.6 1 2 0 0.0009 7 0 0 0 1.35E+08 1.69E+08 - - - 0.6906 0.9921 230117_WJC_METTL3_WT_vs_EV_F07.10691.10691.2 2.19 12-Jun R.VLISSLK[136.11].D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 766.5044 1.22 55384 10691 2 766.505646 384.2595 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2587.1 - 966813 - - - 1.6373 - 1.202 0.139 - 123.2 1 2 0 0.0013 7 0 0 0 1.33E+08 1.09E+08 - - - 0.6502 0.9923 230117_WJC_METTL3_WT_vs_EV_F07.10694.10694.2 0.945 14-Jul K.LLEATELK[136.11].G "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 923.5419 1.11 55385 10694 2 923.542776 462.7782 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 2587.5 - 1.28E+06 - - - 0.9507 - 1.324 0.107 - 114.7 1 2 0 0.0009 8 0 0 0 5.22E+07 4.71E+07 - - - 0.6775 0.9642 230117_WJC_METTL3_WT_vs_EV_F07.10697.10697.2 2.25 12-May K.SVLTPLR[166.11].G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 794.489 1.38 55386 10697 2 794.489274 398.2518 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2587.9 - 1.03E+06 - - - 0.3965 - 1.17 0.057 - 88.5 3 2 0 0.0003 7 0 0 0 8.07E+07 5.87E+07 - - - -0.2538 0.9804 230117_WJC_METTL3_WT_vs_EV_F07.10701.10701.2 0.0866 14-Jul K.YVPLADVK.S "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 903.5066 1.03 55388 10701 2 903.504703 452.7606 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.83 2588.4 - 2.44E+06 - - - -2.0653 - 1.141 0.239 - 164.5 1 2 0 -0.0019 8 0 0 0 9.59E+07 9.30E+07 - - - 1.2035 0.9871 230117_WJC_METTL3_WT_vs_EV_F07.10712.10712.2 0.47 12-May K.SVLTPLR.G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 784.4807 1.3 55393 10712 2 784.481025 393.2476 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2589.8 - 1.53E+06 - - - 0.4283 - 0.944 0.212 - 103.1 1 2 0 0.0003 7 0 0 0 8.08E+07 6.21E+07 - - - 0.4241 0.9963 230117_WJC_METTL3_WT_vs_EV_F07.10751.10751.2 3.36 12-Aug R.IVEGILK.R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 770.4902 2.07 55405 10751 2 770.491333 386.2524 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 2595.3 - 1.37E+06 - - - 1.4822 - 1.604 0.091 - 171.1 1 2 0 0.0011 7 0 0 0 8.86E+08 4.27E+08 - - - 1.2099 0.9962 230117_WJC_METTL3_WT_vs_EV_F07.10752.10752.2 3.38 12-Jun R.IVEGILK[136.11].R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 778.5044 2.07 55406 10752 2 778.50583 390.2595 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 2595.4 - 988062 - - - 1.8484 - 1.28 0.192 - 76.9 1 2 0 0.0014 7 0 0 0 8.86E+08 4.27E+08 - - - 1.2409 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.10764.10764.2 0.0614 12-Aug K.MGITPLR.N "sp|Q12789|TF3C1_HUMAN,sp|O43325|LYRM1_HUMAN,tr|H3BNA8|H3BNA8_HUMAN" 3 786.4422 1.15 55409 10764 2 786.442926 394.2284 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 9.5 2597.2 - 708392 - - - 0.9295 - 1.781 0.266 - 235 1 2 0 0.0007 7 0 0 0 6.81E+07 5.94E+07 - - - 2.8343 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.10766.10766.2 0.00846 26-Jul R.SLYASSPGGVYATR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1427.7045 1.77 55410 10766 2 1427.705102 714.8595 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2597.4 - 53930.6 - - - 0.4259 - 1.424 0.388 - 151.2 1 2 0 0.0006 14 0 0 0 1.01E+07 5.74E+06 - - - 2.7936 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.10774.10774.2 1.05 14-Aug R.ILLAVNGK.V sp|O15173|PGRC2_HUMAN 1 826.5276 2.08 55413 10774 2 826.529047 414.2711 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.75 2598.5 - 576574 - - - 1.7035 - 1.49 0.2 - 161.5 1 2 0 0.0014 8 0 0 0 6.29E+07 3.02E+07 - - - 1.7204 0.9962 230117_WJC_METTL3_WT_vs_EV_F07.10783.10783.2 0.14 12-Jun R.LPPDVLR[166.11].W sp|P78527|PRKDC_HUMAN 1 818.489 1.25 55416 10783 2 818.489763 410.2518 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2599.8 - 657895 - - - 0.9823 - 1.247 0.199 - 114.2 1 2 0 0.0008 7 0 0 0 7.80E+07 6.23E+07 - - - 1.21 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.10793.10793.2 0.0546 18-Aug R.IITEGFEAAK.E sp|P40227|TCPZ_HUMAN 1 1077.5706 12.82 55421 10793 2 1077.572098 539.7926 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 2601.1 - 544610 - - - 1.366 - 1.631 0.243 - 130.2 1 2 0 0.0015 10 0 0 0 4.45E+07 3.47E+06 - - - 2.2008 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.10797.10797.2 0.0825 12-Aug K.LTGMAFR.V "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 794.4109 2.76 55423 10797 2 794.411837 398.2127 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 9.75 2601.6 - 2.95E+06 - - - 1.187 - 1.898 0.334 - 207.8 1 2 0 0.0009 7 0 0 0 1.47E+10 5.32E+09 - - - 3.538 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.10801.10801.2 0.517 12-Jul K.LTGMAFR[166.11].V "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 804.4192 2.76 55425 10801 2 804.419978 403.2169 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 9.75 2602.1 - 3.24E+06 - - - 1.0119 - 1.594 0.192 - 155 1 2 0 0.0008 7 0 0 0 1.47E+10 5.32E+09 - - - 1.9362 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.10828.10828.2 1.91E-05 26-Aug R.SLYASSPGGVYATR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1437.7128 1.77 55435 10828 2 1437.713068 719.8637 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2605.9 - 113195 - - - 0.2114 - 1.67 0.46 - 112.3 1 2 0 0.0003 14 0 0 0 1.01E+07 5.74E+06 - - - 3.7254 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.10841.10841.2 1.44 12-Aug R.MGLVMDR[166.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 830.4018 2.21 55439 10841 2 830.401441 416.2082 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2607.7 - 657308 - - - -0.4323 - 1.624 0.228 - 234.8 1 2 0 -0.0004 7 0 0 0 1.51E+09 6.85E+08 - - - 2.2613 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.10846.10846.2 0.843 12-Aug R.LIITQVR.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 841.5385 0.99 55441 10846 2 841.538185 421.7765 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 9.75 2608.4 - 9.22E+06 - - - -0.4195 - 1.613 0.207 - 216.4 1 2 0 -0.0004 7 0 0 0 5.14E+08 5.20E+08 - - - 2.0847 0.9552 230117_WJC_METTL3_WT_vs_EV_F07.10847.10847.2 0.0319 16-Nov R.PGPLLVSAR[166.11].R sp|Q9NUL7|DDX28_HUMAN 1 918.5526 6.92 55442 10847 2 918.554294 460.2836 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 10.18 2608.5 - 446196 - - - 1.8213 - 2.007 0.273 - 403.3 1 1 0 0.0017 9 0 0 0 5.91E+08 8.55E+07 - - - 3.0723 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.10852.10852.2 0.0102 16-Aug K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 0.83 55444 10852 2 993.583296 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2609.1 - 357589 - - - -1.3627 - 1.528 0.395 - 181 1 2 0 -0.0014 9 0 0 0 9.32E+07 1.13E+08 - - - 3.1846 0.9904 230117_WJC_METTL3_WT_vs_EV_F07.10854.10854.2 1.55 12-Jun R.MGLVMDR.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 820.3935 2.21 55446 10854 2 820.393483 411.204 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2609.3 - 2.06E+06 - - - -0.0573 - 1.248 0.143 - 137.3 1 2 0 0 7 0 0 0 1.51E+09 6.85E+08 - - - 0.7992 0.8798 230117_WJC_METTL3_WT_vs_EV_F07.10863.10863.2 0.471 14-Jun K.LGGLMDPR[166.11].Q "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 867.4512 1.1 55450 10863 2 867.449616 434.7329 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 5.84 2610.4 - 363323 - - - -1.818 - 1.142 0.043 - 56.3 1 2 0 -0.0016 8 0 0 0 2.02E+07 1.83E+07 - - - -0.2414 1 230117_WJC_METTL3_WT_vs_EV_F07.10878.10878.2 1.33E-07 20-Nov K.FGDPVVQSDMK.H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1221.57 0.22 55452 10878 2 1221.56888 611.7923 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.21 2612.7 - 436048 - - - -0.8956 - 1.969 0.599 - 284.9 1 2 0 -0.0011 11 0 0 0 1.43E+07 6.56E+07 - - - 5.2977 1 230117_WJC_METTL3_WT_vs_EV_F07.10888.10888.2 0.000165 22-Nov R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 55455 10888 2 1474.777515 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2614.1 - 377529 - - - -0.3241 - 2.171 0.563 - 257.9 1 2 0 -0.0005 12 0 0 0 4.04E+07 0.00E+00 - - - 5.2388 1 230117_WJC_METTL3_WT_vs_EV_F07.10892.10892.2 0.00052 16-Sep K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 0.83 55456 10892 2 983.575647 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2614.6 - 922271 - - - -0.7452 - 1.996 0.493 - 349.5 1 2 0 -0.0007 9 0 0 0 9.33E+07 1.13E+08 - - - 4.6816 0.999 230117_WJC_METTL3_WT_vs_EV_F07.10907.10907.2 0.031 20-Sep K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 2906.26 55460 10907 2 1106.545747 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2616.9 - 255739 - - - -0.5919 - 1.9 0.341 - 169.1 1 2 0 -0.0007 11 0 0 0 2.17E+09 7.47E+05 - - - 3.2958 0.9942 230117_WJC_METTL3_WT_vs_EV_F07.10912.10912.2 1.14 14-May R.NGYGFINR.N "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 4 939.4563 0.35 55461 10912 2 939.45663 470.7354 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 8.75 2617.6 - 461766 - - - 0.3885 - 1.015 0.262 - 41.2 1 2 0 0.0004 8 0 0 0 1.06E+07 3.04E+07 - - - 1.0209 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.10924.10924.2 0.435 12-Jun R.LILPEAK.V "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN,tr|A8MSZ8|A8MSZ8_HUMAN" 3 782.4902 1.43 55466 10924 2 782.491345 392.2524 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 6 2619.2 - 516019 - - - 1.4748 - 1.16 0.303 - 113.4 1 2 0 0.0012 7 0 0 0 1.35E+08 9.48E+07 - - - 1.7489 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.10934.10934.2 0.0103 16-Aug K.EIAEAYLGK.T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 992.5179 11.72 55468 10934 2 992.518224 497.2662 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 2620.7 - 1.51E+06 - - - 0.3647 - 1.415 0.264 - 257.6 1 2 0 0.0004 9 0 0 0 7.12E+07 6.08E+06 - - - 1.9951 0.9875 230117_WJC_METTL3_WT_vs_EV_F07.10945.10945.2 0.136 12-Jun R.LPPDVLR.W sp|P78527|PRKDC_HUMAN 1 808.4807 1.1 55471 10945 2 808.481072 405.2476 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2622.4 - 545729 - - - 0.4737 - 1.306 0.092 - 118.1 2 2 0 0.0004 7 0 0 0 5.48E+07 4.97E+07 - - - 0.4318 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.10952.10952.2 0.00908 14-Jul R.VITALVER.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 899.544 0.36 55473 10952 2 899.544879 450.7793 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2623.3 - 1.53E+06 - - - 0.9583 - 1.535 0.237 - 126.6 2 2 0 0.0009 8 0 0 0 3.71E+09 1.03E+10 - - - 1.9492 0.9698 230117_WJC_METTL3_WT_vs_EV_F07.10960.10960.2 1.06 12-Jul R.LILPEAK[136.11].V "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN,tr|A8MSZ8|A8MSZ8_HUMAN" 3 790.5044 1.42 55477 10960 2 790.504874 396.2595 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 6 2624.4 - 1.89E+06 - - - 0.611 - 1.118 0.056 - 120.2 1 2 0 0.0005 7 0 0 0 1.36E+08 9.59E+07 - - - -0.1921 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.10981.10981.2 0.917 12-Jul R.LNELLVK.A "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L253|I3L253_HUMAN" 3 827.5117 2.13 55486 10981 2 827.512285 414.7631 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2627.1 - 704261 - - - 0.7625 - 1.552 0.155 - 150.9 1 2 0 0.0006 7 0 0 0 7.48E+08 3.52E+08 - - - 1.5784 0.9801 230117_WJC_METTL3_WT_vs_EV_F07.10986.10986.2 4.72 14-Jun R.LLVVTDPR[166.11].A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 921.5523 2.62 55488 10986 2 921.552525 461.7834 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.84 2627.8 - 456667 - - - 0.2583 - 1.163 0.092 - 94.9 1 2 0 0.0002 8 0 0 0 1.87E+09 7.15E+08 - - - 0.1759 0.8985 230117_WJC_METTL3_WT_vs_EV_F07.10987.10987.2 0.419 14-May R.AVAEMVLK[136.11].G sp|Q96CU9|FXRD1_HUMAN 1 867.4979 4.14 55489 10987 2 867.495565 434.7562 FAD-dependent oxidoreductase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FOXRED1 PE=1 SV=2 6.05 2627.9 - 332230 - - - -2.7205 - 1.112 0.15 - 70.1 3 2 0 -0.0024 8 0 0 0 6.78E+07 1.64E+07 - - - 0.2552 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.10990.10990.2 0.169 14-Jul R.VFVNPSLR.V sp|Q9HBH1|DEFM_HUMAN 1 930.5287 1.05 55491 10990 2 930.528321 466.2716 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 9.72 2628.2 - 7.86E+06 - - - -0.4084 - 1.39 0.204 - 182.8 1 2 0 -0.0004 8 0 0 0 4.84E+08 4.62E+08 - - - 1.5408 0.9922 230117_WJC_METTL3_WT_vs_EV_F07.10992.10992.2 7.77 12-Aug R.LNELLVK[136.11].A "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L253|I3L253_HUMAN" 3 835.5259 2.12 55492 10992 2 835.526362 418.7702 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2628.4 - 1.23E+06 - - - 0.608 - 1.487 0.059 - 155.9 1 2 0 0.0005 7 0 0 0 7.48E+08 3.53E+08 - - - 0.7338 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.10998.10998.2 0.0783 12-Jun K.AC[160.03]TILLR.G "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 845.4793 16.6 55494 10998 2 845.479493 423.7469 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 8.29 2629.2 - 8.27E+06 - - - 0.2176 - 1.305 0.254 - 208.5 1 2 0 0.0002 7 0 0 0 6.14E+08 3.70E+07 - - - 1.7605 0.9744 230117_WJC_METTL3_WT_vs_EV_F07.11009.11009.2 4.09 12-Sep R.LAVYIDR[166.11].V "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|A0A6Q8PFM1|A0A6Q8PFM1_HUMAN,tr|A0A6Q8PF59|A0A6Q8PF59_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 9 858.4839 0.79 55498 11009 2 858.484268 430.2492 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 5.84 2630.6 - 1.10E+06 - - - 0.4601 - 1.303 0.028 - 387.4 2 2 0 0.0004 7 0 0 0 8.30E+07 1.05E+08 - - - -0.0482 0.8846 230117_WJC_METTL3_WT_vs_EV_F07.11035.11035.2 9.86 14-Jun K.ILPVGGIK.E "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN,tr|K7ERR6|K7ERR6_HUMAN" 4 795.5218 1.34 55503 11035 2 795.522034 398.7682 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 8.75 2634.5 - 867366 - - - 0.2627 - 1.016 0.007 - 73.6 2 2 0 0.0002 8 0 0 0 6.61E+07 4.92E+07 - - - -0.994 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.11048.11048.2 0.133 14-Aug R.VITALVER[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 909.5523 0.36 55508 11048 2 909.552942 455.7834 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2636.2 - 6.10E+07 - - - 0.7201 - 1.745 0.252 - 215.9 1 2 0 0.0007 8 0 0 0 3.71E+09 1.03E+10 - - - 2.5812 0.9864 230117_WJC_METTL3_WT_vs_EV_F07.11054.11054.2 0.188 14-Aug R.AIVPLEAR.M "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 867.5178 2.01 55511 11054 2 867.522659 434.7662 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 6.05 2636.9 - 777333 - - - 5.5987 - 1.731 0.192 - 255.1 1 2 0 0.0049 8 0 0 0 1.34E+08 6.68E+07 - - - 2.1124 0.9604 230117_WJC_METTL3_WT_vs_EV_F07.11055.11055.2 5.35 14-Jun K.ILPVGGIK[136.11].E "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN,tr|K7ERR6|K7ERR6_HUMAN" 4 803.536 1.35 55512 11055 2 803.536043 402.7753 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 8.75 2637 - 1.24E+06 - - - 0.0224 - 1.07 0.103 - 84.7 3 2 0 0 8 0 0 0 6.61E+07 4.91E+07 - - - -0.2073 0.9927 230117_WJC_METTL3_WT_vs_EV_F07.11060.11060.2 0.31 18-Jul K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 1.92 55515 11060 2 1008.597432 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2637.6 - 306032 - - - 0.6455 - 1.133 0.188 - 125.8 1 2 0 0.0007 10 0 0 0 1.21E+07 6.27E+06 - - - 0.7779 0.9748 230117_WJC_METTL3_WT_vs_EV_F07.11067.11067.2 1.18 12-Jun R.LISVLNK.S "sp|Q9Y450|HBS1L_HUMAN,tr|H0YDX7|H0YDX7_HUMAN,tr|B7Z524|B7Z524_HUMAN,tr|J3QT46|J3QT46_HUMAN" 4 785.5011 0.48 55518 11067 2 785.501986 393.7578 HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1 8.75 2638.5 - 668573 - - - 1.1407 - 1.257 0.03 - 83 2 2 0 0.0009 7 0 0 0 4.48E+07 9.37E+07 - - - -0.1474 0.9451 230117_WJC_METTL3_WT_vs_EV_F07.11072.11072.2 0.0076 14-Jul Q.VLVLAPTR[166.11].E "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 877.5625 0.89 55520 11072 2 877.563743 439.7885 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.72 2639.1 - 775403 - - - 1.4643 - 1.649 0.296 - 210.3 1 1 0 0.0013 8 0 0 0 1.61E+08 1.80E+08 - - - 2.7353 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.11075.11075.2 2.17E-05 22-Nov K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 2.33 55521 11075 2 1214.652547 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2639.6 - 484528 - - - 1.5478 - 2.159 0.457 - 390.4 1 2 0 0.0019 12 0 0 0 1.08E+08 4.64E+07 - - - 4.4409 1 230117_WJC_METTL3_WT_vs_EV_F07.11076.11076.2 0.000877 22-Nov K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 2.33 55522 11076 2 1222.66652 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2639.7 - 263734 - - - 1.352 - 2.183 0.476 - 358.2 1 2 0 0.0017 12 0 0 0 1.08E+08 4.64E+07 - - - 4.6104 0.9917 230117_WJC_METTL3_WT_vs_EV_F07.11077.11077.2 0.067 14-Aug R.ILMAINGK.V sp|O00264|PGRC1_HUMAN 1 858.4997 0.83 55523 11077 2 858.504568 430.2571 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 8.75 2639.8 - 576117 - - - 5.6599 - 1.519 0.322 - 169.3 1 2 0 0.0049 8 0 0 0 1.12E+08 1.35E+08 - - - 2.6786 0.9072 230117_WJC_METTL3_WT_vs_EV_F07.11081.11081.2 0.592 12-Jul R.LIPTELR[166.11].R "sp|Q96G21|IMP4_HUMAN,tr|F8WCN0|F8WCN0_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN" 4 850.5152 1.15 55525 11081 2 850.519943 426.2649 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2640.3 - 216903 - - - 5.6084 - 1.3 0.104 - 147.8 2 2 0 0.0048 7 0 0 0 2.17E+08 1.89E+08 - - - 0.5045 0.8632 230117_WJC_METTL3_WT_vs_EV_F07.11102.11102.2 0.00677 14-Jul Q.VLVLAPTR.E "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 867.5542 0.89 55534 11102 2 867.555295 434.7844 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.72 2643 - 2.75E+06 - - - 1.276 - 1.409 0.223 - 178 1 1 0 0.0011 8 0 0 0 1.61E+08 1.80E+08 - - - 1.7218 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.11118.11118.2 0.0566 12-Jun R.LIPTELR.R "sp|Q96G21|IMP4_HUMAN,tr|F8WCN0|F8WCN0_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN" 4 840.5069 1.02 55537 11118 2 840.508032 421.2607 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2645.5 - 2.63E+06 - - - 1.3432 - 1.182 0.26 - 151.5 1 2 0 0.0011 7 0 0 0 2.17E+08 2.12E+08 - - - 1.4908 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.11125.11125.2 0.0127 14-Jul K.GIYALAAR.D "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 833.4759 1.09 55539 11125 2 833.47695 417.7452 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 8.75 2646.5 - 904773 - - - 1.2142 - 1.407 0.236 - 164 1 2 0 0.001 8 0 0 0 7.87E+07 7.19E+07 - - - 1.8136 0.9935 230117_WJC_METTL3_WT_vs_EV_F07.11158.11158.2 1.3 12-Jul K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 0.96 55551 11158 2 828.47464 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2651 - 2.04E+06 - - - 1.6078 - 1.414 0.088 - 197.7 1 2 0 0.0013 7 0 0 0 3.83E+10 3.98E+10 - - - 0.7882 0.9692 230117_WJC_METTL3_WT_vs_EV_F07.11173.11173.2 0.339 12-Jul K.FIEIAAR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 818.465 0.96 55558 11173 2 818.464324 410.2398 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2652.9 - 8.11E+06 - - - -0.8724 - 1.328 0.051 - 162.1 1 2 0 -0.0007 7 0 0 0 3.82E+10 3.98E+10 - - - 0.3163 0.9946 230117_WJC_METTL3_WT_vs_EV_F07.11179.11179.2 1.04 12-Jul K.SVLIMGR.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 774.4422 1.48 55559 11179 2 774.443029 388.2284 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.47 2653.8 - 2.21E+06 - - - 1.0769 - 1.197 0.179 - 210.8 1 2 0 0.0008 7 0 0 0 1.21E+08 8.19E+07 - - - 0.9326 0.9632 230117_WJC_METTL3_WT_vs_EV_F07.11184.11184.2 2.43 12-Jun K.IIPVVVK.M "sp|Q96KG9|SCYL1_HUMAN,tr|E9PPN3|E9PPN3_HUMAN,tr|E9PK59|E9PK59_HUMAN,tr|E9PS17|E9PS17_HUMAN" 4 766.5317 1.74 55562 11184 2 766.531965 384.2731 N-terminal kinase-like protein OS=Homo sapiens OX=9606 GN=SCYL1 PE=1 SV=1 8.75 2654.4 - 1.02E+06 - - - 0.3966 - 0.922 0.128 - 94 1 2 0 0.0003 7 0 0 0 6.42E+07 3.69E+07 - - - -0.271 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.11187.11187.2 0.0118 20-Sep K.IGGIGTVPVGR.V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1024.6029 4.44 55564 11187 2 1024.601602 513.3087 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2654.7 - 372036 - - - -1.2951 - 1.867 0.406 - 164.8 1 2 0 -0.0013 11 0 0 0 1.05E+08 2.36E+07 - - - 3.7283 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.11207.11207.2 0.452 14-Aug K.IGVTVLSR[166.11].L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 853.5261 0.9 55569 11207 2 853.525115 427.7703 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2657.6 - 1.34E+06 - - - -1.1212 - 1.813 0.235 - 148.7 1 2 0 -0.001 8 0 0 0 5.41E+08 6.01E+08 - - - 2.5709 0.8495 230117_WJC_METTL3_WT_vs_EV_F07.11222.11222.2 1.08 12-May R.VYLGALK.Y sp|Q6P2Q9|PRP8_HUMAN 1 762.464 0.75 55572 11222 2 762.463668 382.2393 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.56 2659.8 - 1.78E+06 - - - -0.404 - 0.92 0.087 - 73.5 7 2 0 -0.0003 7 0 0 0 3.40E+08 4.51E+08 - - - -0.9582 0.9519 230117_WJC_METTL3_WT_vs_EV_F07.11226.11226.2 1.06 12-Jun R.VYLGALK[136.11].Y sp|Q6P2Q9|PRP8_HUMAN 1 770.4782 1.05 55574 11226 2 770.476702 386.2464 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.56 2660.3 - 2.53E+06 - - - -1.9131 - 1.198 0.114 - 132.1 1 2 0 -0.0015 7 0 0 0 2.98E+08 2.85E+08 - - - 0.455 0.9897 230117_WJC_METTL3_WT_vs_EV_F07.11232.11232.2 0.771 14-Jul R.ILMGSTLR[166.11].K "sp|P10644|KAP0_HUMAN,sp|P31321|KAP1_HUMAN,tr|K7EM13|K7EM13_HUMAN,tr|C9JSK5|C9JSK5_HUMAN,tr|K7EKR1|K7EKR1_HUMAN,tr|K7EPB2|K7EPB2_HUMAN,tr|H7BYW5|H7BYW5_HUMAN" 7 899.5138 1.59 55576 11232 2 899.516064 450.7642 cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1A PE=1 SV=1 9.75 2661 - 863207 - - - 2.5247 - 1.272 0.125 - 130.2 1 2 0 0.0023 8 0 0 0 4.41E+07 2.77E+07 - - - 0.6891 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.11234.11234.2 0.00118 14-Oct K.IGVTVLSR.L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 843.5178 0.9 55577 11234 2 843.516202 422.7662 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2661.3 - 4.20E+06 - - - -1.8968 - 1.896 0.298 - 319.9 1 2 0 -0.0016 8 0 0 0 5.42E+08 6.01E+08 - - - 3.171 0.8577 230117_WJC_METTL3_WT_vs_EV_F07.11266.11266.2 0.032 14-Oct K.LTGVFAPR[166.11].P "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 869.4999 0.98 55585 11266 2 869.498947 435.7572 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2666.1 - 6.16E+06 - - - -1.0477 - 1.865 0.242 - 324 1 1 0 -0.0009 8 0 0 0 2.99E+09 3.06E+09 - - - 2.7079 0.9682 230117_WJC_METTL3_WT_vs_EV_F07.11267.11267.2 2.1 12-Jun K.LPYSTFR[166.11].T "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 892.4682 1.2 55586 11267 2 892.468202 447.2414 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.75 2666.2 - 1.11E+06 - - - -0.0235 - 1.079 0.091 - 133.5 1 2 0 0 7 0 0 0 2.66E+08 2.22E+08 - - - -0.046 0.9908 230117_WJC_METTL3_WT_vs_EV_F07.11276.11276.2 0.712 12-Jun R.VTVPLVR[166.11].R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 792.5097 0.96 55588 11276 2 792.508935 397.2621 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2667.5 - 2.92E+06 - - - -0.9577 - 1.348 0.171 - 146.4 1 2 0 -0.0008 7 0 0 0 5.27E+08 5.52E+08 - - - 1.25 0.9961 230117_WJC_METTL3_WT_vs_EV_F07.11282.11282.2 0.0728 12-Jul R.VTVPLVR.R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 782.5014 0.95 55590 11282 2 782.500681 392.258 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2668.3 - 2.47E+06 - - - -0.9495 - 1.498 0.227 - 203.2 1 2 0 -0.0007 7 0 0 0 5.27E+08 5.53E+08 - - - 1.9979 0.9243 230117_WJC_METTL3_WT_vs_EV_F07.11293.11293.2 0.0405 14-Sep K.LTGVFAPR.P "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 859.4916 0.98 55592 11293 2 859.491587 430.7531 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2670 - 1.86E+07 - - - -0.0012 - 1.789 0.27 - 364.2 1 1 0 0 8 0 0 0 3.00E+09 3.07E+09 - - - 2.7895 0.998 230117_WJC_METTL3_WT_vs_EV_F07.11336.11336.2 0.468 14-Sep K.LGDLGLGR[166.11].F "sp|Q8TDX7|NEK7_HUMAN,sp|Q9HC98|NEK6_HUMAN,tr|Q5TBG7|Q5TBG7_HUMAN,tr|Q5TBG1|Q5TBG1_HUMAN,tr|Q5TBH1|Q5TBH1_HUMAN,tr|Q5TBH2|Q5TBH2_HUMAN,tr|Q5TBH0|Q5TBH0_HUMAN" 7 809.4635 2.05 55603 11336 2 809.463888 405.739 Serine\threonine-protein kinase Nek7 OS=Homo sapiens OX=9606 GN=NEK7 PE=1 SV=1 5.84 2676.4 - 353185 - - - 0.5139 - 1.805 0.139 - 184.8 1 2 0 0.0004 8 0 0 0 2.36E+07 1.15E+07 - - - 1.8486 0.9872 230117_WJC_METTL3_WT_vs_EV_F07.11340.11340.2 0.604 14-Aug R.NLLLAGAK[136.11].V sp|Q9P2R3|ANFY1_HUMAN 1 806.5105 4.16 55604 11340 2 806.510632 404.2625 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 8.75 2676.9 - 277002 - - - 0.1153 - 1.472 0.043 - 146.7 1 2 0 0.0001 8 0 0 0 9.58E+07 2.30E+07 - - - 0.5246 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.11352.11352.2 0.032 18-Jul K.NGQDLGVAFK[136.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1055.5491 1.5 55609 11352 2 1055.550354 528.7818 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2678.4 - 167167 - - - 1.1795 - 1.464 0.245 - 151 1 2 0 0.0012 10 0 0 0 6.31E+07 4.21E+07 - - - 1.9141 0.9913 230117_WJC_METTL3_WT_vs_EV_F07.11355.11355.2 0.382 18-Jun K.NGQDLGVAFK.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1047.5349 1.6 55610 11355 2 1047.53495 524.7747 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2678.8 - 289480 - - - 0.0391 - 1.163 0.204 - 69.8 2 2 0 0 10 0 0 0 6.71E+07 4.21E+07 - - - 0.8348 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.11367.11367.2 0.0496 12-Jun K.FMTDPIR.L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 878.432 0.93 55614 11367 2 878.433356 440.2233 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2680.6 - 1.31E+06 - - - 1.5163 - 1.225 0.271 - 173.8 1 2 0 0.0013 7 0 0 0 1.37E+08 1.48E+08 - - - 1.6852 0.9939 230117_WJC_METTL3_WT_vs_EV_F07.11373.11373.2 1.87 12-Jun K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 0.96 55618 11373 2 828.474536 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2681.3 - 3.22E+06 - - - 1.4822 - 1.333 0.119 - 158.1 1 2 0 0.0012 7 0 0 0 3.83E+10 3.98E+10 - - - 0.8303 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.11381.11381.2 0.177 12-Jul K.FMTDPIR[166.11].L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 888.4403 0.96 55620 11381 2 888.442433 445.2274 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2682.5 - 2.60E+06 - - - 2.4076 - 1.338 0.266 - 192.7 1 2 0 0.0021 7 0 0 0 1.42E+08 1.48E+08 - - - 1.9276 0.9963 230117_WJC_METTL3_WT_vs_EV_F07.11390.11390.2 0.000293 14-Aug K.FGPALSVK[136.11].V "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 825.484 4.28 55622 11390 2 825.486572 413.7493 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.75 2683.8 - 2.65E+06 - - - 3.1279 - 1.733 0.145 - 188.5 1 2 0 0.0026 8 0 0 0 3.53E+09 8.24E+08 - - - 1.7695 0.9702 230117_WJC_METTL3_WT_vs_EV_F07.11407.11407.2 2.27 14-Jul K.ALSVGLVK.G "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 3 785.5011 1.67 55633 11407 2 785.503178 393.7578 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 8.8 2686 - 186383 - - - 2.6582 - 1.184 0.061 - 104.8 1 2 0 0.0021 8 0 0 0 1.32E+08 7.89E+07 - - - 0.0003 0.9939 230117_WJC_METTL3_WT_vs_EV_F07.11408.11408.2 0.0673 12-Jul K.MMEIMTR[166.11].E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 920.4157 0.86 55634 11408 2 920.417518 461.2151 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2686.1 - 288904 - - - 1.9372 - 1.117 0.202 - 147.4 1 2 0 0.0018 7 0 0 0 1.42E+08 1.65E+08 - - - 0.883 0.9931 230117_WJC_METTL3_WT_vs_EV_F07.11411.11411.2 0.702 14-Jun K.LLLGDAPR.L "sp|Q96C00|ZBTB9_HUMAN,tr|A0A087X1K1|A0A087X1K1_HUMAN" 2 853.5022 0.66 55635 11411 2 853.504375 427.7584 Zinc finger and BTB domain-containing protein 9 OS=Homo sapiens OX=9606 GN=ZBTB9 PE=1 SV=1 5.84 2686.5 - 448671 - - - 2.6046 - 1.331 0.151 - 83.8 1 2 0 0.0022 8 0 0 0 3.35E+07 5.07E+07 - - - 1.0179 0.9592 230117_WJC_METTL3_WT_vs_EV_F07.11412.11412.2 5.66 14-May K.VLEC[160.03]DIIK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 988.5263 0.64 55636 11412 2 988.527259 495.2704 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 2686.7 - 153966 - - - 0.9519 - 1.135 0.018 - 66.9 1 2 0 0.0009 8 0 0 0 1.25E+07 1.97E+07 - - - -0.4444 0.9959 230117_WJC_METTL3_WT_vs_EV_F07.11418.11418.2 1.05 14-Oct R.VLAVTAIR[166.11].E sp|P22102|PUR2_HUMAN 1 851.5468 2.47 55640 11418 2 851.548722 426.7807 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2687.4 - 494840 - - - 2.2477 - 1.73 0.079 - 229 1 2 0 0.0019 8 0 0 0 4.17E+08 1.69E+08 - - - 1.277 0.9957 230117_WJC_METTL3_WT_vs_EV_F07.11420.11420.2 0.436 20-Jun K.ETTIDGEELVK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1240.6278 0.74 55642 11420 2 1240.628334 621.3212 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4 2687.6 - 84990.1 - - - 0.4199 - 1.145 0.267 - 86.9 2 2 0 0.0005 11 0 0 0 3.05E+06 4.10E+06 - - - 1.2447 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.11423.11423.2 0.937 14-Jun R.VLAVTAIR.E sp|P22102|PUR2_HUMAN 1 841.5385 2.47 55643 11423 2 841.539819 421.7765 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2688 - 1.38E+06 - - - 1.5222 - 1.647 0.151 - 105.9 1 2 0 0.0013 8 0 0 0 4.17E+08 1.69E+08 - - - 1.6607 0.9942 230117_WJC_METTL3_WT_vs_EV_F07.11429.11429.2 0.0424 12-Jun K.MMEIMTR.E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 910.4075 0.86 55646 11429 2 910.410247 456.211 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2688.8 - 2.42E+06 - - - 3.0558 - 1.123 0.264 - 85 1 2 0 0.0028 7 0 0 0 1.42E+08 1.65E+08 - - - 1.3576 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.11433.11433.2 0.0317 16-Sep R.MVGGVLVER[166.11].T sp|Q9UHV9|PFD2_HUMAN 1 968.5353 1.44 55648 11433 2 968.537397 485.2749 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 5.75 2689.3 - 1.82E+06 - - - 2.2095 - 1.549 0.27 - 221.2 1 2 0 0.0021 9 0 0 0 7.35E+07 5.10E+07 - - - 2.3006 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.11440.11440.2 0.00144 12-Jul K.MMVAGFK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 790.3961 0.89 55651 11440 2 790.397333 396.2053 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2690.2 - 1.95E+06 - - - 1.5574 - 1.494 0.422 - 240 1 2 0 0.0012 7 0 0 0 6.68E+09 7.47E+09 - - - 3.4295 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.11448.11448.2 0.00013 12-Jun K.MMVAGFK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 782.3819 0.89 55653 11448 2 782.382461 392.1982 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2691.4 - 3.67E+06 - - - 0.7145 - 1.531 0.479 - 168.2 1 2 0 0.0006 7 0 0 0 6.68E+09 7.47E+09 - - - 3.9283 0.9961 230117_WJC_METTL3_WT_vs_EV_F07.11449.11449.2 0.381 12-Aug K.YLDEIVK.E sp|P12270|TPR_HUMAN 1 878.4749 2 55654 11449 2 878.475156 440.2447 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.37 2691.5 - 1.14E+06 - - - 0.2516 - 1.359 0.183 - 186.4 1 2 0 0.0002 7 0 0 0 5.39E+07 2.70E+07 - - - 1.3645 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.11464.11464.2 0.773 14-Oct K.IVGYVLAK[136.11].M "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN" 4 869.5466 1.28 55661 11464 2 869.547472 435.7806 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 8.59 2693.4 - 1.80E+06 - - - 1.0143 - 1.431 0.264 - 248.1 1 2 0 0.0009 8 0 0 0 1.89E+08 1.47E+08 - - - 2.0715 1 230117_WJC_METTL3_WT_vs_EV_F07.11465.11465.3 2.51E-07 14/52 K.SQIHDIVLVGGSTR.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1480.7998 30.43 55662 11465 3 1480.80161 494.6072 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2693.5 - 366671 - - - 1.2284 - 2.673 0.483 - 279.1 1 2 0 0.0018 14 0 0 0 1.46E+07 4.80E+05 - - - 6.5374 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.11467.11467.2 0.00256 18-Jul K.C[160.03]PFTGNVSIR[166.11].G "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1159.5683 0.92 55664 11467 2 1159.569006 580.7915 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.25 2693.7 - 147957 - - - 0.5675 - 1.299 0.399 - 169.6 1 2 0 0.0007 10 0 0 0 4.08E+06 4.41E+06 - - - 2.718 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.11473.11473.2 5.61E-05 18-Nov K.YEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1178.5932 999 55668 11473 2 1178.594286 590.3039 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2694.5 - 340111 - - - 0.9622 - 2.219 0.279 - 502.6 1 2 0 0.0011 10 0 0 0 2.48E+07 0.00E+00 - - - 3.3262 0.9892 230117_WJC_METTL3_WT_vs_EV_F07.11476.11476.2 0.378 14-Jul K.IVGYVLAK.M "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN" 4 861.5324 1.28 55669 11476 2 861.532876 431.7735 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 8.59 2694.9 - 2.82E+06 - - - 0.5641 - 1.102 0.16 - 117.5 1 2 0 0.0005 8 0 0 0 1.89E+08 1.47E+08 - - - 0.5155 0.9949 230117_WJC_METTL3_WT_vs_EV_F07.11481.11481.2 1.13 14-Jun R.GLGGIMVK.R sp|O94776|MTA2_HUMAN 1 773.4469 1.26 55672 11481 2 773.447694 387.7307 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 2695.5 - 1.07E+06 - - - 0.9671 - 1.095 0.226 - 98.2 1 2 0 0.0007 8 0 0 0 5.49E+07 4.34E+07 - - - 0.9837 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.11491.11491.2 0.0338 12-Jul R.IVYLYTK.K sp|P49207|RL34_HUMAN 1 898.5164 0.74 55676 11491 2 898.516047 450.2655 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 8.5 2696.9 - 1.13E+07 - - - -0.3984 - 1.499 0.405 - 168.4 1 2 0 -0.0004 7 0 0 0 9.15E+08 1.24E+09 - - - 3.3148 0.9433 230117_WJC_METTL3_WT_vs_EV_F07.11555.11555.2 11.3 12-Aug K.LAPFIAK[136.11].R "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN,tr|K7ELX4|K7ELX4_HUMAN" 3 766.4833 1.69 55696 11555 2 766.481709 384.2489 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 8.75 2705.8 - 3.06E+06 - - - -2.0248 - 1.289 0.073 - 171 1 2 0 -0.0016 7 0 0 0 4.69E+08 2.77E+08 - - - 0.3841 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.11584.11584.2 0.00719 16-Oct R.LLSPLSSAR[166.11].L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 952.5581 1.09 55704 11584 2 952.558656 477.2863 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 2710.1 - 1.65E+06 - - - 0.5826 - 1.816 0.301 - 324.1 1 2 0 0.0006 9 0 0 0 2.15E+08 1.99E+08 - - - 2.9901 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.11585.11585.2 0.2 14-Sep R.TIAPIIGR[166.11].T sp|Q99459|CDC5L_HUMAN 1 849.5312 3.26 55705 11585 2 849.531469 425.7729 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.41 2710.2 - 1.05E+06 - - - 0.3661 - 1.385 0.237 - 245.2 1 2 0 0.0003 8 0 0 0 9.30E+07 2.85E+07 - - - 1.7737 0.9943 230117_WJC_METTL3_WT_vs_EV_F07.11587.11587.2 0.2 14-May R.LLVPGTYK[136.11].L "sp|O75976|CBPD_HUMAN,tr|J3QQJ4|J3QQJ4_HUMAN" 2 897.5415 0.82 55706 11587 2 897.542757 449.778 Carboxypeptidase D OS=Homo sapiens OX=9606 GN=CPD PE=1 SV=2 8.59 2710.6 - 231115 - - - 1.396 - 1.203 0.173 - 56.7 1 2 0 0.0013 8 0 0 0 1.63E+07 1.99E+07 - - - 0.8758 0.9962 230117_WJC_METTL3_WT_vs_EV_F07.11594.11594.2 1.7 14-Sep R.TIAPIIGR.T sp|Q99459|CDC5L_HUMAN 1 839.5229 1.09 55710 11594 2 839.523537 420.7687 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.41 2711.4 - 763138 - - - 0.7731 - 1.466 0.141 - 204.9 1 2 0 0.0006 8 0 0 0 2.72E+07 2.49E+07 - - - 1.2359 0.9925 230117_WJC_METTL3_WT_vs_EV_F07.11600.11600.2 0.943 12-Aug R.YLLYGEK[136.11].G "sp|P51398|RT29_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GYL9|V9GYL9_HUMAN" 3 892.4786 0.36 55712 11600 2 892.479893 447.2466 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 6 2712.2 - 575917 - - - 1.4824 - 1.344 0.095 - 221.5 1 2 0 0.0013 7 0 0 0 5.84E+07 1.61E+08 - - - 0.679 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.11602.11602.2 0.0106 14-Jul K.GLYPAPLK[136.11].L "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 865.5153 1.55 55713 11602 2 865.516624 433.7649 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.59 2712.4 - 522329 - - - 1.5413 - 1.378 0.261 - 160.5 1 2 0 0.0013 8 0 0 0 6.41E+07 4.14E+07 - - - 1.9353 0.988 230117_WJC_METTL3_WT_vs_EV_F07.11604.11604.2 2.32 14-Aug R.IGLETSLR[166.11].Y sp|Q9Y230|RUVB2_HUMAN 1 897.5159 1.7 55714 11604 2 897.513452 449.7652 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6 2712.7 - 173622 - - - -2.7298 - 1.533 0.225 - 123.2 1 2 0 -0.0024 8 0 0 0 4.08E+07 2.40E+07 - - - 1.9906 0.9916 230117_WJC_METTL3_WT_vs_EV_F07.11618.11618.2 4.38 14-Sep R.IGLETSLR.Y sp|Q9Y230|RUVB2_HUMAN 1 887.5076 0.46 55721 11618 2 887.50922 444.7611 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6 2714.4 - 602828 - - - 1.7893 - 1.337 0.097 - 199.3 1 2 0 0.0016 8 0 0 0 4.12E+07 8.89E+07 - - - 0.6329 0.9864 230117_WJC_METTL3_WT_vs_EV_F07.11624.11624.2 0.0651 16-Oct R.LLPAELPAK[136.11].R sp|P78527|PRKDC_HUMAN 1 958.5943 1.3 55724 11624 2 958.601908 480.3044 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2715.3 - 459056 - - - 7.97 - 1.71 0.453 - 254.2 1 2 0 0.0076 9 0 0 0 6.05E+07 4.66E+07 - - - 3.9366 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.11627.11627.2 0.0224 16-Oct R.LLSPLSSAR.L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 942.5498 1.08 55726 11627 2 942.551238 472.2822 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 2715.7 - 5.15E+06 - - - 1.4928 - 1.838 0.284 - 382.6 1 2 0 0.0014 9 0 0 0 2.15E+08 1.99E+08 - - - 2.8991 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.11634.11634.2 0.314 12-Aug R.IDGVLIR.M sp|O75663|TIPRL_HUMAN 1 784.4807 2.05 55731 11634 2 784.481369 393.2476 TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2 5.84 2716.4 - 983718 - - - 0.8668 - 1.613 0.18 - 136.5 1 2 0 0.0007 7 0 0 0 8.29E+07 4.05E+07 - - - 1.8851 0.9943 230117_WJC_METTL3_WT_vs_EV_F07.11640.11640.2 0.66 14-Jun K.GLYPAPLK.L "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 857.5011 1.07 55734 11640 2 857.502359 429.7578 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.59 2717.2 - 548409 - - - 1.4799 - 1.145 0.193 - 104.2 1 2 0 0.0013 8 0 0 0 2.64E+07 2.48E+07 - - - 0.8745 0.9586 230117_WJC_METTL3_WT_vs_EV_F07.11641.11641.2 0.303 20-May K.HFSGLEEAVYR.N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1306.6306 2.34 55735 11641 2 1306.634412 654.3226 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 2717.3 - 980875 - - - 2.9174 - 0.972 0.204 - 23.3 21 2 0 0.0038 11 0 0 0 8.07E+06 3.45E+06 - - - -0.1209 0.9771 230117_WJC_METTL3_WT_vs_EV_F07.11644.11644.2 6.4 12-May R.FPGAYLK.G "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 794.4327 1.41 55736 11644 2 794.433802 398.2236 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.59 2717.7 - 1.15E+06 - - - 1.4174 - 1.192 0.079 - 49.8 4 2 0 0.0011 7 0 0 0 1.14E+08 8.11E+07 - - - -0.0883 0.8957 230117_WJC_METTL3_WT_vs_EV_F07.11647.11647.2 0.0755 16-Jul N.LVIITAGAR[166.11].Q "sp|Q9BYZ2|LDH6B_HUMAN,sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 7 922.5839 0.94 55738 11647 2 922.584911 462.2992 L-lactate dehydrogenase A-like 6B OS=Homo sapiens OX=9606 GN=LDHAL6B PE=1 SV=3 9.75 2718 - 3.22E+06 - - - 1.072 - 1.737 0.205 - 132.9 2 1 0 0.001 9 0 0 0 1.59E+08 1.70E+08 - - - 2.0178 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.11676.11676.2 0.0201 16-Jul R.LLPAELPAK.R sp|P78527|PRKDC_HUMAN 1 950.5801 1.3 55746 11676 2 950.581281 476.2973 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2722.2 - 1.39E+06 - - - 1.2761 - 1.316 0.379 - 157.6 1 2 0 0.0012 9 0 0 0 6.05E+07 4.66E+07 - - - 2.6343 1 230117_WJC_METTL3_WT_vs_EV_F07.11680.11680.2 1.04E-06 12-Aug K.C[160.03]PVFVVR.W "sp|Q9C0J8|WDR33_HUMAN,tr|C9J8B4|C9J8B4_HUMAN" 2 875.4687 1.84 55747 11680 2 875.469402 438.7416 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 8.25 2722.8 - 2.02E+06 - - - 0.7516 - 1.817 0.565 - 399 1 2 0 0.0007 7 0 0 0 1.25E+08 6.80E+07 - - - 5.1061 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.11682.11682.2 0.00339 12-Jul K.C[160.03]PVFVVR[166.11].W "sp|Q9C0J8|WDR33_HUMAN,tr|C9J8B4|C9J8B4_HUMAN" 2 885.477 2.82 55749 11682 2 885.477147 443.7458 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 8.25 2723 - 1.05E+06 - - - 0.1502 - 1.358 0.347 - 219.9 1 2 0 0.0001 7 0 0 0 2.00E+08 7.10E+07 - - - 2.5735 0.9837 230117_WJC_METTL3_WT_vs_EV_F07.11686.11686.2 0.131 20-Jun K.VLFSSNGGVVK.G "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 1105.6132 1.15 55751 11686 2 1105.617589 553.8139 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.72 2723.5 - 317257 - - - 4.0068 - 1.221 0.214 - 74.5 2 2 0 0.0044 11 0 0 0 1.32E+07 1.14E+07 - - - 1.0259 0.9701 230117_WJC_METTL3_WT_vs_EV_F07.11687.11687.2 2.76 14-Jun K.MVSAAFMK.K "sp|P25205|MCM3_HUMAN,tr|Q7Z6P5|Q7Z6P5_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 4 883.4296 2.83 55752 11687 2 883.4299 442.7221 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 8.5 2723.6 - 1.78E+06 - - - 0.3611 - 1.119 0.085 - 126 2 2 0 0.0003 8 0 0 0 6.27E+07 2.22E+07 - - - -0.1267 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.11688.11688.2 0.0108 20-Aug K.VLFSSNGGVVK[136.11].G "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 1113.6274 1.15 55753 11688 2 1113.628589 557.821 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.72 2723.7 - 310595 - - - 1.1045 - 1.572 0.391 - 149.3 1 2 0 0.0012 11 0 0 0 1.32E+07 1.14E+07 - - - 3.1523 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.11690.11690.2 1.02 12-Jul K.LLQEIVR.S "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 869.5335 1.5 55754 11690 2 869.533871 435.774 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6 2723.9 - 1.11E+06 - - - 0.4819 - 1.387 0.264 - 163.2 1 2 0 0.0004 7 0 0 0 8.55E+07 5.70E+07 - - - 2.0273 0.9966 230117_WJC_METTL3_WT_vs_EV_F07.11697.11697.2 0.614 14-Aug K.NIILGGVK.A "sp|P22314|UBA1_HUMAN,tr|Q5JRS3|Q5JRS3_HUMAN,tr|Q5JRS2|Q5JRS2_HUMAN,tr|Q5JRS0|Q5JRS0_HUMAN,tr|Q5JRS1|Q5JRS1_HUMAN,tr|Q5JRR9|Q5JRR9_HUMAN" 6 812.512 2.71 55757 11697 2 812.513406 407.2633 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 8.75 2724.9 - 558241 - - - 1.744 - 1.691 0.091 - 160.1 1 2 0 0.0014 8 0 0 0 5.28E+07 1.95E+07 - - - 1.297 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.11700.11700.2 0.158 14-Oct R.LLGQIVDR[166.11].C sp|Q96I24|FUBP3_HUMAN 1 922.5475 1.48 55758 11700 2 922.548567 462.281 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2725.4 - 1.52E+06 - - - 1.1176 - 1.577 0.21 - 272.9 1 2 0 0.001 8 0 0 0 1.31E+09 8.86E+08 - - - 1.9656 0.9913 230117_WJC_METTL3_WT_vs_EV_F07.11712.11712.2 0.889 12-Aug R.VAGIFPR.L "sp|O96005|CLPT1_HUMAN,tr|K7EJ16|K7EJ16_HUMAN" 2 758.4439 0.84 55763 11712 2 758.446077 380.2292 Cleft lip and palate transmembrane protein 1 OS=Homo sapiens OX=9606 GN=CLPTM1 PE=1 SV=1 9.72 2727 - 557253 - - - 2.8585 - 1.426 0.106 - 178.5 1 2 0 0.0022 7 0 0 0 7.07E+07 8.43E+07 - - - 0.9477 1 230117_WJC_METTL3_WT_vs_EV_F07.11714.11714.3 3.85E-12 19/84 K.DHTPSQELALTQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2270.0411 999 55765 11714 3 2270.040675 757.6876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2727.3 - 211367 - - - -0.1859 - 3.914 0.696 - 221.7 1 2 0 -0.0004 22 0 0 0 5.51E+06 0.00E+00 - - - 9.5347 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.11729.11729.2 0.0464 16-Sep K.NDLAVVDVR[166.11].L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1009.5432 0.76 55772 11729 2 1009.546087 505.7789 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.21 2729.2 - 390376 - - - 2.8805 - 1.841 0.373 - 355.9 1 2 0 0.0029 9 0 0 0 1.60E+07 2.09E+07 - - - 3.5607 0.9894 230117_WJC_METTL3_WT_vs_EV_F07.11737.11737.2 0.22 20-Jul R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 0.92 55775 11737 2 1174.720868 588.3655 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2730.3 - 135361 - - - 3.7107 - 1.453 0.157 - 78.4 1 2 0 0.0044 11 0 0 0 6.90E+07 7.48E+07 - - - 1.21 0.9395 230117_WJC_METTL3_WT_vs_EV_F07.11746.11746.2 6.38 20-Jun R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 0.91 55778 11746 2 1166.705888 584.3584 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2731.5 - 135296 - - - 3.0676 - 1.171 0.058 - 77.4 3 2 0 0.0036 11 0 0 0 6.80E+07 7.48E+07 - - - -0.3178 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.11748.11748.2 0.0385 20-Jul K.LLAETVAPAVR[166.11].G "sp|Q9BSJ8|ESYT1_HUMAN,tr|F8VZB1|F8VZB1_HUMAN" 2 1148.6793 0.74 55779 11748 2 1148.678669 575.3469 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6 2731.7 - 236179 - - - -0.531 - 1.685 0.291 - 109 1 2 0 -0.0006 11 0 0 0 1.60E+07 2.16E+07 - - - 2.6016 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.11749.11749.2 0.174 16-Apr K.SC[160.03]AHDWVYE.- "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 3 1165.4499 - 55780 11749 2 1165.450626 583.7322 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 4.71 2731.9 - 169418 - - - 0.6581 - 0.805 0.366 - 49.2 1 2 0 0.0008 9 0 0 0 - - - - - 1.1165 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.11751.11751.2 0.056 14-Sep R.LLGQIVDR.C sp|Q96I24|FUBP3_HUMAN 1 912.5393 1.48 55781 11751 2 912.540673 457.2769 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2732.1 - 2.91E+07 - - - 1.5419 - 1.739 0.266 - 210.7 1 2 0 0.0014 8 0 0 0 1.31E+09 8.86E+08 - - - 2.674 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.11759.11759.2 0.115 14-Oct R.LLGQIVDR[166.11].C sp|Q96I24|FUBP3_HUMAN 1 922.5475 1.48 55786 11759 2 922.548369 462.281 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2733.1 - 2.46E+07 - - - 0.9029 - 1.908 0.205 - 307.6 1 2 0 0.0008 8 0 0 0 1.31E+09 8.86E+08 - - - 2.5033 1 230117_WJC_METTL3_WT_vs_EV_F07.11760.11760.3 7.15E-07 Oct-68 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 6.01 55787 11760 3 2070.874184 691.296 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2733.2 - 122169 - - - 3.811 - 2.202 0.722 - 71.8 1 2 0 0.0079 18 0 0 0 5.15E+06 8.56E+05 - - - 8.553 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.11761.11761.2 0.0354 12-Jun K.YVMVVYK.R "sp|Q9BPX3|CND3_HUMAN,tr|D6RA93|D6RA93_HUMAN" 2 900.4779 17.54 55788 11761 2 900.480269 451.2462 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 8.5 2733.3 - 586389 - - - 2.6186 - 1.194 0.365 - 115.5 1 2 0 0.0024 7 0 0 0 1.60E+08 9.13E+06 - - - 2.298 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.11766.11766.2 0.0014 20-Oct K.LLAETVAPAVR.G "sp|Q9BSJ8|ESYT1_HUMAN,tr|F8VZB1|F8VZB1_HUMAN" 2 1138.671 0.78 55791 11766 2 1138.67484 570.3428 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6 2733.9 - 268113 - - - 3.3644 - 1.86 0.402 - 347.3 1 2 0 0.0038 11 0 0 0 1.60E+07 2.05E+07 - - - 3.6878 0.9882 230117_WJC_METTL3_WT_vs_EV_F07.11771.11771.2 1.97 14-Jul R.LVSLIGSK[136.11].T "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 823.5259 2.04 55793 11771 2 823.527246 412.7702 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 2734.5 - 1.23E+06 - - - 1.6903 - 1.192 0.109 - 84.8 1 2 0 0.0014 8 0 0 0 9.54E+07 4.67E+07 - - - 0.3753 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.11786.11786.2 0.064 14-Jul K.LGDIMGVK[136.11].K sp|Q92620|PRP16_HUMAN 1 839.4666 0.25 55800 11786 2 839.468099 420.7406 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38 PE=1 SV=2 5.84 2736.4 - 493261 - - - 1.7559 - 1.458 0.227 - 79.7 1 2 0 0.0015 8 0 0 0 1.51E+07 5.97E+07 - - - 1.8544 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.11791.11791.3 0.0306 15/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 0.76 55802 11791 3 1166.704723 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2737.1 - 3.25E+06 - - - 2.0691 - 2.883 0.228 - 218.8 1 2 0 0.0024 11 0 0 0 2.88E+08 3.80E+08 - - - 4.0893 0.8668 230117_WJC_METTL3_WT_vs_EV_F07.11793.11793.2 0.128 18-Aug L.LASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1053.6182 0.78 55803 11793 2 1053.61978 527.8164 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2737.3 - 211331 - - - 1.4569 - 1.632 0.182 - 125.7 1 1 0 0.0015 10 0 0 0 1.10E+07 1.40E+07 - - - 1.752 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.11798.11798.3 0.0746 13/40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 0.76 55804 11798 3 1174.718129 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2738.1 - 4.78E+06 - - - 1.3791 - 2.217 0.245 - 120.6 1 2 0 0.0016 11 0 0 0 2.88E+08 3.80E+08 - - - 3.5328 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.11799.11799.2 0.0828 12-Jul R.VVVEYLR.A sp|O60645|EXOC3_HUMAN 1 876.5069 1.63 55805 11799 2 876.507582 439.2607 Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3 5.97 2738.2 - 416951 - - - 0.7747 - 1.423 0.283 - 190.2 1 2 0 0.0007 7 0 0 0 5.94E+07 3.64E+07 - - - 2.2488 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.11802.11802.2 0.0554 12-Jul R.VFVVMEK.L "sp|Q15139|KPCD1_HUMAN,sp|O94806|KPCD3_HUMAN,sp|Q9BZL6|KPCD2_HUMAN,tr|M0R2Z8|M0R2Z8_HUMAN,tr|F8WBA3|F8WBA3_HUMAN" 5 850.4623 0.25 55806 11802 2 850.464427 426.2384 Serine\threonine-protein kinase D1 OS=Homo sapiens OX=9606 GN=PRKD1 PE=1 SV=2 5.97 2738.6 - 253816 - - - 2.5469 - 1.514 0.182 - 149.3 1 2 0 0.0022 7 0 0 0 1.70E+07 6.76E+07 - - - 1.6987 0.9581 230117_WJC_METTL3_WT_vs_EV_F07.11824.11824.2 0.0392 12-Jul K.VEPVYLR.G sp|Q8NDT2|RB15B_HUMAN 1 874.4913 0.9 55816 11824 2 874.493809 438.2529 Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3 5.97 2741.6 - 901032 - - - 2.9228 - 1.31 0.015 - 192.1 2 2 0 0.0026 7 0 0 0 1.46E+08 1.62E+08 - - - -0.1279 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.11825.11825.2 0.000362 16-Jul K.ESYSVYVYK[136.11].V "sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 10 1144.5532 1.36 55817 11825 2 1144.55275 573.2839 Histone H2B type 2-F OS=Homo sapiens OX=9606 GN=H2BC18 PE=1 SV=3 6.1 2741.8 - 195361 - - - -0.3853 - 1.461 0.436 - 152.8 1 2 0 -0.0004 9 0 0 0 8.86E+06 6.53E+06 - - - 3.358 0.9556 230117_WJC_METTL3_WT_vs_EV_F07.11829.11829.2 0.00128 16-Oct L.ASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 940.5342 0.95 55819 11829 2 940.536992 471.2744 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 2742.2 - 474675 - - - 2.9887 - 2.096 0.378 - 413.1 1 1 0 0.0028 9 0 0 0 2.45E+07 2.59E+07 - - - 3.973 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.11848.11848.2 0.0249 16-Nov K.VGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 911.5804 2.01 55827 11848 2 911.581887 456.7975 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2744.7 - 692059 - - - 1.6279 - 2.144 0.239 - 265.6 1 2 0 0.0015 9 0 0 0 7.87E+08 3.91E+08 - - - 3.0122 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.11857.11857.2 0.284 16-Nov K.VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 919.5946 2.01 55831 11857 2 919.595694 460.8046 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2746 - 1.32E+06 - - - 1.1864 - 2.079 0.263 - 320.6 1 2 0 0.0011 9 0 0 0 7.87E+08 3.91E+08 - - - 3.1006 0.9499 230117_WJC_METTL3_WT_vs_EV_F07.11858.11858.2 2.41E-05 18-Sep K.YEELQVTVGR.H sp|P35908|K22E_HUMAN 1 1192.6088 999 55832 11858 2 1193.612181 597.3117 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.53 2746.2 - 83575.5 - - - 841.3312 - 1.699 0.456 - 290.1 1 2 0 1.0034 10 0 0 0 1.97E+06 0.00E+00 - - - 3.5735 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.11861.11861.2 5.43 12-Aug K.LEDLIVK[136.11].D "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 836.5099 2 55834 11861 2 836.510166 419.2622 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2746.5 - 2.57E+06 - - - 0.3539 - 1.907 0.13 - 173.6 1 2 0 0.0003 7 0 0 0 1.72E+09 8.61E+08 - - - 2.0465 0.9586 230117_WJC_METTL3_WT_vs_EV_F07.11868.11868.2 5.74 12-Jun R.LLLPGTR.A sp|Q6P087|RUSD3_HUMAN 1 768.4858 1.42 55838 11868 2 768.487177 385.2502 Mitochondrial mRNA pseudouridine synthase RPUSD3 OS=Homo sapiens OX=9606 GN=RPUSD3 PE=1 SV=3 9.75 2747.3 - 828447 - - - 1.8257 - 1.177 0.043 - 130.9 5 2 0 0.0014 7 0 0 0 5.77E+07 4.07E+07 - - - -0.4377 0.998 230117_WJC_METTL3_WT_vs_EV_F07.11875.11875.2 0.828 12-Sep K.LEDLIVK.D "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 828.4957 2 55840 11875 2 828.496916 415.2551 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2748.3 - 1.18E+07 - - - 1.5039 - 2.018 0.063 - 266.5 1 2 0 0.0012 7 0 0 0 1.72E+09 8.61E+08 - - - 1.7306 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.11876.11876.2 2.04 12-Aug R.LGLTEIR[166.11].K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 810.4839 1.19 55841 11876 2 810.484667 406.2492 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2748.4 - 2.27E+06 - - - 0.9797 - 1.678 0.147 - 199.1 1 2 0 0.0008 7 0 0 0 1.30E+09 1.09E+09 - - - 1.7665 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.11880.11880.2 0.0405 18-Aug K.LITPAVVSER[166.11].L sp|P62851|RS25_HUMAN 1 1093.6371 1.09 55843 11880 2 1093.638229 547.8258 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 6 2748.9 - 203351 - - - 1.0515 - 1.577 0.26 - 166.1 1 2 0 0.0011 10 0 0 0 1.53E+07 1.40E+07 - - - 2.2325 0.9941 230117_WJC_METTL3_WT_vs_EV_F07.11882.11882.2 2.2 12-Jul R.LGLTEIR.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 800.4756 1.19 55844 11882 2 800.476612 401.2451 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2749.1 - 3.33E+06 - - - 1.2605 - 1.459 0.083 - 147.7 1 2 0 0.001 7 0 0 0 1.30E+09 1.09E+09 - - - 0.8506 0.996 230117_WJC_METTL3_WT_vs_EV_F07.11883.11883.2 0.0216 12-Jun K.LDPVLYR[166.11].K "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 884.4995 0.91 55845 11883 2 884.501331 443.257 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 5.84 2749.1 - 3.08E+06 - - - 2.0441 - 1.291 0.188 - 175.5 1 2 0 0.0018 7 0 0 0 1.49E+08 1.63E+08 - - - 1.2383 0.9878 230117_WJC_METTL3_WT_vs_EV_F07.11887.11887.2 2.23 12-Jun K.FLEATLR.S "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN" 2 848.4756 0.72 55847 11887 2 848.476886 425.2451 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 6 2749.7 - 443192 - - - 1.5121 - 1.317 0.076 - 108 2 2 0 0.0013 7 0 0 0 4.07E+07 5.67E+07 - - - 0.3399 0.9311 230117_WJC_METTL3_WT_vs_EV_F07.11905.11905.2 4.31 12-May R.LLLPGTR[166.11].A sp|Q6P087|RUSD3_HUMAN 1 778.494 1.42 55852 11905 2 778.494385 390.2543 Mitochondrial mRNA pseudouridine synthase RPUSD3 OS=Homo sapiens OX=9606 GN=RPUSD3 PE=1 SV=3 9.75 2752.2 - 766296 - - - 0.438 - 1.106 0.011 - 88.7 2 2 0 0.0003 7 0 0 0 5.80E+07 4.08E+07 - - - -0.6931 0.9556 230117_WJC_METTL3_WT_vs_EV_F07.11906.11906.2 7.01 12-May R.LAVYC[160.03]LK.D "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 865.4732 0.69 55853 11906 2 865.47416 433.7439 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.2 2752.4 - 457464 - - - 1.1543 - 1.129 0.008 - 64.2 1 2 0 0.001 7 0 0 0 4.53E+07 6.53E+07 - - - -0.5158 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.11933.11933.2 0.0623 14-Aug K.LIEQYALR.E sp|Q9NUQ3|TXLNG_HUMAN 1 1004.5655 1.39 55862 11933 2 1004.565377 503.29 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2756.2 - 591912 - - - -0.1035 - 1.551 0.227 - 202.9 1 2 0 -0.0001 8 0 0 0 4.23E+07 3.04E+07 - - - 2.0413 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.11934.11934.2 1.33 14-Aug K.LIEQYALR[166.11].E sp|Q9NUQ3|TXLNG_HUMAN 1 1014.5738 1.55 55863 11934 2 1014.57444 508.2942 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2756.3 - 513628 - - - 0.6791 - 1.493 0.166 - 186.9 1 2 0 0.0007 8 0 0 0 4.73E+07 3.05E+07 - - - 1.4756 0.9923 230117_WJC_METTL3_WT_vs_EV_F07.11942.11942.2 0.0729 12-May K.LMPTQWR.T sp|Q99459|CDC5L_HUMAN 1 930.4746 1.15 55865 11942 2 930.475735 466.2446 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.75 2757.5 - 1.25E+06 - - - 1.266 - 1.081 0.203 - 103.3 2 2 0 0.0012 7 0 0 0 5.69E+07 4.94E+07 - - - 0.6523 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.11983.11983.2 0.201 14-Jun K.VPYLAVAR[166.11].T "sp|P18858|DNLI1_HUMAN,tr|F5GZ28|F5GZ28_HUMAN,tr|M0R0Q7|M0R0Q7_HUMAN,tr|B4E135|B4E135_HUMAN" 4 897.5312 2.2 55884 11983 2 897.532064 449.7729 DNA ligase 1 OS=Homo sapiens OX=9606 GN=LIG1 PE=1 SV=1 8.72 2762.9 - 400908 - - - 1.0094 - 1.33 0.241 - 72.8 2 2 0 0.0009 8 0 0 0 3.16E+07 1.44E+07 - - - 1.5464 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.11993.11993.2 0.165 12-Aug K.FVNLYTR.E "sp|Q15650|TRIP4_HUMAN,tr|H0YL91|H0YL91_HUMAN" 2 911.4865 2.01 55890 11993 2 911.48704 456.7505 Activating signal cointegrator 1 OS=Homo sapiens OX=9606 GN=TRIP4 PE=1 SV=4 8.75 2764.2 - 534462 - - - 0.5902 - 1.649 0.228 - 152.1 1 2 0 0.0005 7 0 0 0 2.39E+07 1.19E+07 - - - 2.3097 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.11996.11996.2 0.08 24-Aug R.GGIGAGLGGGLC[160.03]R.R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1143.5819 0.62 55893 11996 2 1143.584086 572.7982 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2764.6 - 140365 - - - 1.9325 - 1.58 0.176 - 105.5 2 2 0 0.0022 13 0 0 0 9.83E+06 1.58E+07 - - - 1.3798 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.12005.12005.2 0.117 14-Jun K.FLTGYEVK.V sp|Q8NI60|COQ8A_HUMAN 1 955.5015 0.53 55900 12005 2 955.503341 478.758 "Atypical kinase COQ8A, mitochondrial OS=Homo sapiens OX=9606 GN=COQ8A PE=1 SV=1" 6 2765.7 - 306966 - - - 1.9435 - 1.224 0.345 - 82.9 1 2 0 0.0019 8 0 0 0 1.20E+07 2.25E+07 - - - 2.1982 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.12008.12008.2 0.105 24-Dec R.GGIGAGLGGGLC[160.03]R[166.11].R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1153.5901 0.62 55901 12008 2 1153.59351 577.8023 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2766.1 - 449005 - - - 2.9161 - 2.042 0.311 - 338.8 1 2 0 0.0034 13 0 0 0 9.83E+06 1.58E+07 - - - 3.1693 0.9886 230117_WJC_METTL3_WT_vs_EV_F07.12010.12010.2 0.0157 16-Aug R.LITGLGVGR[166.11].E sp|Q9BQG0|MBB1A_HUMAN 1 894.5526 1.1 55903 12010 2 894.557063 448.2836 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 9.75 2766.4 - 531626 - - - 4.9656 - 1.272 0.29 - 116.9 1 2 0 0.0044 9 0 0 0 1.50E+08 1.36E+08 - - - 1.8776 0.9929 230117_WJC_METTL3_WT_vs_EV_F07.12026.12026.2 0.515 12-May R.FALVTPK[136.11].K sp|P49792|RBP2_HUMAN 1 782.4782 0.92 55912 12026 2 782.480226 392.2464 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.75 2768.4 - 802390 - - - 2.6199 - 1.206 0.203 - 58.9 2 2 0 0.0021 7 0 0 0 6.35E+07 6.89E+07 - - - 0.9987 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.12027.12027.2 0.0095 12-Jul R.AAYIYIR[166.11].G "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|B4DE93|B4DE93_HUMAN,tr|E9PJL9|E9PJL9_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PLC6|E9PLC6_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN" 8 878.489 5.19 55913 12027 2 878.490591 440.2518 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.63 2768.5 - 542418 - - - 1.8577 - 1.281 0.284 - 213.4 1 2 0 0.0016 7 0 0 0 1.19E+08 2.29E+07 - - - 1.9228 0.9032 230117_WJC_METTL3_WT_vs_EV_F07.12031.12031.2 0.0209 16-Jul P.PVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 979.6066 1.31 55915 12031 2 979.609848 490.8106 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 9.18 2769 - 152634 - - - 3.2983 - 1.386 0.402 - 101.4 1 1 0 0.0032 9 0 0 0 5.12E+06 3.91E+06 - - - 2.9535 0.862 230117_WJC_METTL3_WT_vs_EV_F07.12035.12035.2 1.82 18-May K.LIEC[160.03]DTLSR[166.11]K.K "sp|Q5T5U3|RHG21_HUMAN,tr|A0A087WW76|A0A087WW76_HUMAN,tr|A0A7P0TAS2|A0A7P0TAS2_HUMAN,tr|A0A805TBS0|A0A805TBS0_HUMAN,tr|A0A452Q6Z5|A0A452Q6Z5_HUMAN" 5 1243.647 - 55918 12035 2 1243.654714 622.8308 Rho GTPase-activating protein 21 OS=Homo sapiens OX=9606 GN=ARHGAP21 PE=1 SV=2 6.06 2769.5 - 595209 - - - 6.2092 - 1.039 0.18 - 70.1 1 2 0 0.0077 10 0 0 0 - - - - - 0.4748 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.12050.12050.2 0.424 12-Jul K.ILLVDER.S "sp|A5YKK6|CNOT1_HUMAN,tr|H3BMZ2|H3BMZ2_HUMAN" 2 856.5018 1.25 55924 12050 2 856.504491 429.2582 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.37 2771.4 - 1.97E+06 - - - 3.1208 - 1.632 0.165 - 178.4 1 2 0 0.0027 7 0 0 0 1.01E+08 8.07E+07 - - - 1.8108 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.12053.12053.2 0.102 14-Oct R.ALLGPALK.D sp|P35250|RFC2_HUMAN 1 781.5062 1.86 55926 12053 2 781.505997 391.7604 Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3 8.8 2771.7 - 1.39E+06 - - - -0.2278 - 1.747 0.285 - 307.3 1 2 0 -0.0002 8 0 0 0 1.36E+08 7.28E+07 - - - 2.8286 0.9365 230117_WJC_METTL3_WT_vs_EV_F07.12069.12069.2 2.67 16-Jul K.IILEPMDLK.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1070.6046 155.08 55934 12069 2 1070.601493 536.3096 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.37 2773.7 - 699766 - - - -2.8731 - 1.575 0.043 - 150.4 1 2 0 -0.0031 9 0 0 0 3.09E+07 1.99E+05 - - - 0.6718 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.12083.12083.2 0.0652 12-Aug K.VPVNLLR[166.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 819.5206 1.17 55940 12083 2 819.520192 410.7676 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2775.5 - 1.30E+06 - - - -0.4893 - 1.492 0.324 - 356.3 1 2 0 -0.0004 7 0 0 0 1.81E+08 1.55E+08 - - - 2.7017 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.12085.12085.2 0.0607 16-Aug R.LITGLGVGR.E sp|Q9BQG0|MBB1A_HUMAN 1 884.5444 1.13 55941 12085 2 884.543584 443.2795 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 9.75 2775.7 - 1.93E+06 - - - -0.8671 - 1.506 0.343 - 152.4 1 2 0 -0.0008 9 0 0 0 1.54E+08 1.36E+08 - - - 2.7587 0.9888 230117_WJC_METTL3_WT_vs_EV_F07.12087.12087.2 0.379 12-Aug K.IDPLLPK.E sp|Q9BYD6|RM01_HUMAN 1 794.4902 2.46 55943 12087 2 794.489924 398.2524 "39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2" 5.84 2775.9 - 1.41E+06 - - - -0.3361 - 1.291 0.129 - 172 1 2 0 -0.0003 7 0 0 0 3.08E+08 1.25E+08 - - - 0.803 1 230117_WJC_METTL3_WT_vs_EV_F07.12091.12091.2 0.00109 24-Dec R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 55944 12091 2 1302.609154 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2776.4 - 8.53E+06 - - - -0.0322 - 2.224 0.5 - 272.7 1 2 0 0 13 0 0 0 2.33E+09 0.00E+00 - - - 4.7854 1 230117_WJC_METTL3_WT_vs_EV_F07.12097.12097.2 2.01E-05 20-Nov R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 9241.7 55945 12097 2 1201.608818 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2777.4 - 1.49E+06 - - - -0.2655 - 2.175 0.504 - 177.8 1 2 0 -0.0003 11 0 0 0 8.94E+09 9.67E+05 - - - 4.8655 0.9849 230117_WJC_METTL3_WT_vs_EV_F07.12099.12099.2 0.221 18-Aug K.QLVTNAC[160.03]LIK[136.11].E "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 3 1166.6573 0.34 55946 12099 2 1166.655401 584.3359 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 8.22 2777.6 - 204863 - - - -1.6106 - 1.296 0.192 - 160.6 1 2 0 -0.0019 10 0 0 0 2.11E+06 6.16E+06 - - - 1.1823 0.998 230117_WJC_METTL3_WT_vs_EV_F07.12117.12117.2 0.00386 12-Jul R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.82 55954 12117 2 852.483302 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2779.7 - 1.97E+07 - - - -0.4141 - 1.431 0.292 - 142.1 1 2 0 -0.0004 7 0 0 0 2.78E+09 1.53E+09 - - - 2.3331 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.12144.12144.3 0.000123 14/40 R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 3712.78 55966 12144 3 1201.608159 401.5437 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2783.2 - 3.48E+06 - - - -0.8139 - 2.34 0.241 - 295.9 1 2 0 -0.001 11 0 0 0 5.02E+08 1.35E+05 - - - 3.6418 0.9671 230117_WJC_METTL3_WT_vs_EV_F07.12146.12146.2 0.192 14-Sep R.TFGVSPLR.R sp|Q5T750|XP32_HUMAN 1 875.4865 47.89 55967 12146 2 875.491862 438.7505 Skin-specific protein 32 OS=Homo sapiens OX=9606 GN=XP32 PE=1 SV=1 9.41 2783.4 - 1.62E+06 - - - 6.1223 - 1.297 0.242 - 207.4 1 2 0 0.0054 8 0 0 0 1.07E+08 2.23E+06 - - - 1.611 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.12147.12147.2 0.207 16-Jul K.IPTPIVGVK.R "sp|P51003|PAPOA_HUMAN,tr|G3XAH6|G3XAH6_HUMAN,tr|H0YJL4|H0YJL4_HUMAN" 3 922.5852 2.34 55968 12147 2 922.585968 462.2999 Poly(A) polymerase alpha OS=Homo sapiens OX=9606 GN=PAPOLA PE=1 SV=4 8.75 2783.5 - 264901 - - - 0.8823 - 1.254 0.27 - 98.6 1 2 0 0.0008 9 0 0 0 8.50E+06 3.64E+06 - - - 1.6898 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.12151.12151.2 0.369 14-Jun K.ILFTEATR.L "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 949.5233 1.83 55969 12151 2 949.523437 475.7689 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 6 2784.1 - 1.46E+06 - - - 0.1632 - 1.388 0.282 - 100.2 1 2 0 0.0002 8 0 0 0 5.70E+07 3.11E+07 - - - 2.1126 0.9611 230117_WJC_METTL3_WT_vs_EV_F07.12157.12157.2 0.138 12-Jun K.GLVLMSR[166.11].A "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 16 784.4505 1.41 55972 12157 2 784.449824 393.2325 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 9.75 2784.9 - 6.03E+06 - - - -0.8171 - 1.41 0 - 164.4 1 2 0 -0.0006 7 0 0 0 7.20E+08 5.12E+08 - - - 0.1295 0.999 230117_WJC_METTL3_WT_vs_EV_F07.12163.12163.2 0.0049 14-Aug K.VVNPYYLR.V sp|Q13131|AAPK1_HUMAN 1 1022.5549 1.62 55975 12163 2 1022.554052 512.2847 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4 8.56 2785.8 - 275033 - - - -0.8449 - 1.711 0.38 - 202.4 1 2 0 -0.0009 8 0 0 0 1.32E+07 8.18E+06 - - - 3.4672 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.12170.12170.2 0.00858 16-Aug M.PLPVALQTR[166.11].L "sp|O60828|PQBP1_HUMAN,tr|A0A5H1ZRR1|A0A5H1ZRR1_HUMAN" 2 1003.6054 1.17 55979 12170 2 1003.605801 502.81 Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1 10.18 2786.5 - 763891 - - - 0.4145 - 1.382 0.34 - 253 1 2 0 0.0004 9 0 0 0 3.75E+07 3.21E+07 - - - 2.4881 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.12182.12182.2 0.0357 16-Sep R.NVIEAVYSR[166.11].L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1059.5588 1.23 55985 12182 2 1059.559032 530.7867 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 2787.9 - 512474 - - - 0.1916 - 1.603 0.321 - 224.3 1 2 0 0.0002 9 0 0 0 7.35E+07 5.99E+07 - - - 2.777 0.8903 230117_WJC_METTL3_WT_vs_EV_F07.12190.12190.2 0.0387 16-Aug A.AAAAFLQQR[166.11].N "sp|Q7Z5Q1|CPEB2_HUMAN,tr|A0A5K1VW71|A0A5K1VW71_HUMAN,tr|A0A5K1VW93|A0A5K1VW93_HUMAN,tr|A0A5K1VW61|A0A5K1VW61_HUMAN,tr|A0A5K1VW79|A0A5K1VW79_HUMAN" 5 984.538 0.2 55987 12190 2 984.538562 493.2763 Cytoplasmic polyadenylation element-binding protein 2 OS=Homo sapiens OX=9606 GN=CPEB2 PE=2 SV=3 9.79 2789 - 347314 - - - 0.5363 - 1.496 0.255 - 182.4 1 1 0 0.0005 9 0 0 0 3.62E+06 1.80E+07 - - - 2.0896 0.9684 230117_WJC_METTL3_WT_vs_EV_F07.12194.12194.2 0.00943 14-Aug R.VFVSPLAK[136.11].K "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 867.5309 0.76 55989 12194 2 867.526597 434.7727 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 8.72 2789.4 - 1.49E+06 - - - -5.0062 - 1.518 0.288 - 209.3 1 2 0 -0.0043 8 0 0 0 3.64E+08 4.81E+08 - - - 2.4256 0.9592 230117_WJC_METTL3_WT_vs_EV_F07.12200.12200.2 0.491 12-Jul K.VPVNLLR.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 809.5123 1.17 55992 12200 2 809.510085 405.7634 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2790.1 - 1.17E+06 - - - -2.7646 - 1.13 0.208 - 147 1 2 0 -0.0022 7 0 0 0 1.81E+08 1.55E+08 - - - 0.9638 0.9966 230117_WJC_METTL3_WT_vs_EV_F07.12201.12201.2 0.355 14-Jul R.LLEEGVLR.Q "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 927.5389 2.3 55993 12201 2 927.538204 464.7767 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 2790.2 - 1.08E+06 - - - -0.7849 - 1.385 0.272 - 144 1 2 0 -0.0007 8 0 0 0 1.36E+08 5.93E+07 - - - 2.0321 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.12203.12203.2 0.00472 12-Aug R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.46 55994 12203 2 844.469713 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2790.4 - 5.55E+07 - - - 0.3055 - 1.332 0.329 - 199.2 1 2 0 0.0003 7 0 0 0 1.36E+10 9.31E+09 - - - 2.3793 0.8475 230117_WJC_METTL3_WT_vs_EV_F07.12207.12207.2 0.728 16-Aug E.VDELPSLMK.L "sp|Q9UHL0|DDX25_HUMAN,tr|E9PR46|E9PR46_HUMAN,tr|J3QL17|J3QL17_HUMAN,tr|J3QRJ6|J3QRJ6_HUMAN" 4 1030.5369 41.13 55996 12207 2 1030.53697 516.2757 ATP-dependent RNA helicase DDX25 OS=Homo sapiens OX=9606 GN=DDX25 PE=1 SV=2 4.37 2790.9 - 1.32E+06 - - - 0.0844 - 1.793 0.161 - 123 1 1 0 0.0001 9 0 0 0 2.62E+09 6.36E+07 - - - 1.9193 0.995 230117_WJC_METTL3_WT_vs_EV_F07.12208.12208.2 4.74 12-Jul K.IPVIIER.Y "sp|A6NCE7|MP3B2_HUMAN,sp|Q9GZQ8|MLP3B_HUMAN,sp|Q9H492|MLP3A_HUMAN,tr|H3BTL1|H3BTL1_HUMAN" 4 838.5276 1.36 55997 12208 2 838.527919 420.2711 Microtubule-associated proteins 1A\1B light chain 3 beta 2 OS=Homo sapiens OX=9606 GN=MAP1LC3B2 PE=2 SV=1 6 2791 - 1.41E+06 - - - 0.3339 - 1.606 0.082 - 198.3 1 2 0 0.0003 7 0 0 0 5.86E+07 4.31E+07 - - - 1.1477 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.12211.12211.2 0.0109 16-Jul K.LVPVGYGIK[136.11].K sp|P24534|EF1B_HUMAN 1 952.5837 0.72 55998 12211 2 952.583065 477.2991 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2791.4 - 5.07E+06 - - - -0.6708 - 1.349 0.434 - 138.7 1 2 0 -0.0006 9 0 0 0 1.48E+09 2.06E+09 - - - 3.1124 0.9703 230117_WJC_METTL3_WT_vs_EV_F07.12224.12224.2 0.39 12-Jul R.ILLYAC[160.03]R[166.11].N "sp|P36954|RPB9_HUMAN,tr|K7EKS1|K7EKS1_HUMAN" 2 917.5032 1.07 56002 12224 2 917.502011 459.7589 DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1 8.22 2793.2 - 1.30E+06 - - - -1.3275 - 1.299 0.091 - 172.7 1 2 0 -0.0012 7 0 0 0 8.15E+07 7.63E+07 - - - 0.5416 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.12235.12235.2 0.98 14-Aug R.VFVSPLAK.K "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 859.5167 0.76 56004 12235 2 859.519229 430.7656 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 8.72 2794.9 - 1.07E+07 - - - 2.8958 - 1.388 0.262 - 211.2 1 2 0 0.0025 8 0 0 0 3.64E+08 4.80E+08 - - - 1.9642 0.9302 230117_WJC_METTL3_WT_vs_EV_F07.12239.12239.2 0.0106 12-Jul R.PVWADYR[166.11].R "sp|Q9Y676|RT18B_HUMAN,tr|A0A0G2JIC6|A0A0G2JIC6_HUMAN" 2 915.4478 1.22 56005 12239 2 915.448463 458.7312 "28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1" 6.26 2795.5 - 1.07E+06 - - - 0.7002 - 1.288 0.366 - 182.4 1 1 0 0.0006 7 0 0 0 5.79E+07 4.76E+07 - - - 2.546 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.12246.12246.2 0.0041 20-Nov R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 999 56008 12246 2 1264.630016 633.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2796.4 - 1.00E+06 - - - 0.0664 - 2.136 0.43 - 226.1 1 2 0 0.0001 11 0 0 0 3.03E+07 0.00E+00 - - - 4.2701 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.12256.12256.2 0.000667 16-Aug K.LVPVGYGIK.K sp|P24534|EF1B_HUMAN 1 944.5695 0.72 56011 12256 2 944.568697 473.292 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2797.9 - 2.15E+07 - - - -0.8544 - 1.653 0.475 - 284.4 1 2 0 -0.0008 9 0 0 0 1.47E+09 2.06E+09 - - - 4.0031 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.12262.12262.2 0.0025 14-Jul R.MVDFAGVK[136.11].D "sp|P21964|COMT_HUMAN,tr|E7EUU8|E7EUU8_HUMAN,tr|E7EMS6|E7EMS6_HUMAN,tr|F8WBW9|F8WBW9_HUMAN,tr|H7BZ45|H7BZ45_HUMAN,tr|A0A7I2V3G7|A0A7I2V3G7_HUMAN,tr|A0A7I2V370|A0A7I2V370_HUMAN" 7 873.451 1.11 56013 12262 2 873.453351 437.7328 Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT PE=1 SV=2 5.59 2798.7 - 932851 - - - 2.7202 - 1.412 0.258 - 105 1 2 0 0.0024 8 0 0 0 1.09E+08 9.82E+07 - - - 1.9864 0.9894 230117_WJC_METTL3_WT_vs_EV_F07.12264.12264.2 0.00572 12-Jun K.LSIVPVR[166.11].R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 792.5097 0.86 56014 12264 2 792.508518 397.2621 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2798.9 - 4.07E+07 - - - -1.4839 - 1.403 0.175 - 121.1 1 2 0 -0.0012 7 0 0 0 3.16E+09 3.65E+09 - - - 1.4061 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.12285.12285.2 0.0118 14-Aug K.TPVIVTLK[136.11].E "sp|Q9Y4L1|HYOU1_HUMAN,tr|A0A087WWI4|A0A087WWI4_HUMAN,tr|K7EQK2|K7EQK2_HUMAN,tr|A0A087WW13|A0A087WW13_HUMAN,tr|Q9BST8|Q9BST8_HUMAN,tr|J3KTF1|J3KTF1_HUMAN,tr|A0A494C039|A0A494C039_HUMAN,tr|J3QL06|J3QL06_HUMAN,tr|A0A087X214|A0A087X214_HUMAN,tr|A0A087X054|A0A087X054_HUMAN,tr|E9PJ21|E9PJ21_HUMAN,tr|J3QLE9|J3QLE9_HUMAN,tr|J3QQH7|J3QQH7_HUMAN" 13 877.5728 1.4 56020 12285 2 877.573264 439.7937 Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1 8.41 2801.8 - 383735 - - - 0.523 - 1.544 0.313 - 131.4 1 2 0 0.0005 8 0 0 0 1.65E+07 1.18E+07 - - - 2.6627 0.9937 230117_WJC_METTL3_WT_vs_EV_F07.12287.12287.2 0.0683 12-Aug K.LSIVPVR.R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 782.5014 0.86 56021 12287 2 782.500482 392.258 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2802 - 5.38E+07 - - - -1.2038 - 1.621 0.152 - 247.4 1 2 0 -0.0009 7 0 0 0 3.16E+09 3.65E+09 - - - 1.6939 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.12319.12319.2 0.000138 16-Aug K.VLEGMEVVR[166.11].K "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1040.5564 0.09 56033 12319 2 1040.555825 521.2855 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.53 2806.5 - 671350 - - - -0.5391 - 1.786 0.41 - 227 1 2 0 -0.0006 9 0 0 0 4.15E+06 4.83E+07 - - - 3.747 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.12342.12342.2 0.334 14-Jul K.IIGDTFVK.L sp|P49915|GUAA_HUMAN 1 891.5066 2.5 56042 12342 2 891.506822 446.7606 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.84 2809.6 - 3.30E+06 - - - 0.2838 - 1.27 0.302 - 99.6 1 2 0 0.0003 8 0 0 0 3.30E+08 1.32E+08 - - - 1.9924 0.999 230117_WJC_METTL3_WT_vs_EV_F07.12345.12345.2 0.000724 12-Sep R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.41 56044 12345 2 852.483522 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2810 - 8.19E+07 - - - -0.156 - 1.589 0.325 - 231.1 1 2 0 -0.0001 7 0 0 0 1.09E+10 7.79E+09 - - - 2.9088 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.12355.12355.2 0.0571 12-Jul K.YLYEIAR.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 926.4862 53.3 56050 12355 2 926.486599 464.2504 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6 2811.2 - 1.19E+07 - - - 0.4652 - 1.405 0.221 - 182.9 1 2 0 0.0004 7 0 0 0 9.22E+08 1.73E+07 - - - 1.7506 1 230117_WJC_METTL3_WT_vs_EV_F07.12357.12357.2 8.21E-06 18-Oct K.NLQYYDISAK.S "sp|P62826|RAN_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|B4DV51|B4DV51_HUMAN,tr|F5H018|F5H018_HUMAN" 5 1213.5979 3.55 56052 12357 2 1213.599659 607.8062 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 5.83 2811.5 - 396094 - - - 1.4469 - 1.782 0.547 - 220.4 1 2 0 0.0018 10 0 0 0 6.02E+06 1.70E+06 - - - 4.6932 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.12403.12403.2 0.113 14-Sep R.LADIVVPR.G sp|Q9NWZ5|UCKL1_HUMAN 1 881.5335 2.37 56080 12403 2 881.535442 441.774 Uridine-cytidine kinase-like 1 OS=Homo sapiens OX=9606 GN=UCKL1 PE=1 SV=2 5.84 2817.1 - 541911 - - - 2.2574 - 1.952 0.235 - 273.3 1 2 0 0.002 8 0 0 0 2.00E+07 8.47E+06 - - - 2.7933 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.12418.12418.2 0.000221 20-Oct R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 36.33 56088 12418 2 1201.610048 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2819 - 239786 - - - 0.7582 - 1.943 0.45 - 223.1 1 2 0 0.0009 11 0 0 0 2.76E+07 7.61E+05 - - - 4.1613 0.9701 230117_WJC_METTL3_WT_vs_EV_F07.12423.12423.2 0.0479 16-Oct R.PLISVYSEK[136.11].G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1042.579 0.8 56090 12423 2 1042.580548 522.2968 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.42 2819.8 - 417449 - - - 1.4733 - 1.911 0.366 - 399.6 1 1 0 0.0015 9 0 0 0 5.50E+07 6.85E+07 - - - 3.6174 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.12430.12430.2 0.0358 12-Aug R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.46 56093 12430 2 844.470127 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2820.6 - 2.02E+07 - - - 0.7958 - 1.314 0.211 - 203.7 1 2 0 0.0007 7 0 0 0 1.36E+10 9.31E+09 - - - 1.4645 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.12450.12450.2 1.52 12-Jul R.LLSVNIR.V sp|P07814|SYEP_HUMAN 1 813.5072 1.44 56100 12450 2 813.507512 407.7609 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 9.75 2823.4 - 1.07E+06 - - - 0.3368 - 1.498 0.146 - 126.3 1 2 0 0.0003 7 0 0 0 2.45E+08 1.70E+08 - - - 1.3998 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.12454.12454.2 0.0305 14-Aug K.LIGEYGLR.N "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 919.5127 0.81 56102 12454 2 919.513718 460.7636 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 2823.9 - 5.60E+06 - - - 1.0886 - 1.599 0.142 - 157.8 1 2 0 0.001 8 0 0 0 3.45E+09 4.27E+09 - - - 1.5051 0.8854 230117_WJC_METTL3_WT_vs_EV_F07.12476.12476.2 1.71 20-Jun R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 999 56108 12476 2 1068.660765 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 2827.1 - 595717 - - - 6.0534 - 1.361 0.11 - 66.6 2 2 0 0.0065 11 0 0 0 6.38E+07 0.00E+00 - - - 0.5508 0.9917 230117_WJC_METTL3_WT_vs_EV_F07.12504.12504.2 0.177 14-Jun K.QYFEQFGK[136.11].V "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|J3KTC1|J3KTC1_HUMAN" 7 1053.5011 1.37 56117 12504 2 1053.504769 527.7578 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6 2830.8 - 158374 - - - 3.4865 - 1.074 0.275 - 102.9 1 2 0 0.0037 8 0 0 0 6.01E+06 4.40E+06 - - - 1.2863 0.983 230117_WJC_METTL3_WT_vs_EV_F07.12517.12517.2 1.65 14-Jun K.AGLYGLPR[166.11].R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|A0A0U1RRG3|A0A0U1RRG3_HUMAN" 3 855.4842 2.26 56123 12517 2 855.485221 428.7494 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.79 2832.5 - 570762 - - - 1.1841 - 1.018 0.156 - 78 2 2 0 0.001 8 0 0 0 5.52E+08 2.44E+08 - - - 0.1122 0.9949 230117_WJC_METTL3_WT_vs_EV_F07.12519.12519.2 0.136 12-Jun K.TC[160.03]PLLLR[166.11].V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 881.5032 1.23 56125 12519 2 881.501885 441.7589 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2832.7 - 1.01E+06 - - - -1.5247 - 1.313 0.296 - 132.4 1 2 0 -0.0013 7 0 0 0 1.58E+09 1.28E+09 - - - 2.0897 0.998 230117_WJC_METTL3_WT_vs_EV_F07.12530.12530.2 0.0117 12-Jul K.TC[160.03]PLLLR.V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 871.495 1.23 56130 12530 2 871.494158 436.7548 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2834.1 - 1.30E+06 - - - -0.9191 - 1.47 0.325 - 220.2 1 2 0 -0.0008 7 0 0 0 1.58E+09 1.28E+09 - - - 2.6619 0.8688 230117_WJC_METTL3_WT_vs_EV_F07.12536.12536.2 3.62 12-Jun K.VLFTVGK.L sp|Q9Y4C2|TCAF1_HUMAN 1 762.464 2.31 56134 12536 2 762.466664 382.2393 TRPM8 channel-associated factor 1 OS=Homo sapiens OX=9606 GN=TCAF1 PE=1 SV=3 8.72 2834.8 - 1.72E+06 - - - 3.5254 - 1.132 0.047 - 90.3 10 2 0 0.0027 7 0 0 0 3.17E+07 1.38E+07 - - - -0.6665 1 230117_WJC_METTL3_WT_vs_EV_F07.12565.12565.3 3.26E-08 16/72 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 56.09 56143 12565 3 2080.024815 694.3481 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2839.1 - 263991 - - - 1.0971 - 2.754 0.622 - 87.7 1 2 0 0.0023 19 0 0 0 1.04E+08 1.86E+06 - - - 7.9629 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.12567.12567.4 0.000214 17/108 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 3.43 56144 12567 4 2080.028383 521.0129 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2839.3 - 1.16E+06 - - - 2.8125 - 1.915 0.383 - 60.8 1 2 0 0.0059 19 0 0 0 3.56E+07 1.04E+07 - - - 2.7778 0.9709 230117_WJC_METTL3_WT_vs_EV_F07.12569.12569.2 2.18 18-May R.TIAQDYGVLK.A "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1106.5972 1.35 56145 12569 2 1106.598928 554.3059 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.5 2839.5 - 125166 - - - 1.5841 - 1.011 0.112 - 52.8 2 2 0 0.0018 10 0 0 0 1.63E+07 1.21E+07 - - - -0.2363 0.8811 230117_WJC_METTL3_WT_vs_EV_F07.12572.12572.2 4.44 18-Jun R.SINQPVAFVR.R "sp|Q9GZT3|SLIRP_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|H0YJI1|H0YJI1_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1129.6244 1.21 56146 12572 2 1129.629212 565.8195 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 9.47 2840 - 154712 - - - 4.266 - 1.162 0.053 - 78.3 2 2 0 0.0048 10 0 0 0 8.19E+06 6.77E+06 - - - -0.2844 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.12593.12593.2 0.0758 12-Jul R.WLGEPIK[136.11].A "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 849.484 0.45 56156 12593 2 849.48614 425.7493 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6 2842.5 - 3.01E+06 - - - 2.5309 - 1.265 0.286 - 234 1 2 0 0.0022 7 0 0 0 1.37E+09 3.05E+09 - - - 1.8976 0.998 230117_WJC_METTL3_WT_vs_EV_F07.12598.12598.2 1.81 14-Aug R.LPLQDVYK[136.11].L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 982.5579 5.08 56158 12598 2 982.559413 492.2862 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2843.2 - 2.74E+06 - - - 1.5572 - 1.744 0.139 - 273.4 1 2 0 0.0015 8 0 0 0 2.87E+09 5.64E+08 - - - 1.7446 0.9599 230117_WJC_METTL3_WT_vs_EV_F07.12605.12605.2 1.63 18-Jul R.TIAQDYGVLK[136.11].A "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1114.6114 1.35 56161 12605 2 1114.610339 558.313 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.5 2844.1 - 211260 - - - -0.9295 - 1.201 0.082 - 90.3 1 2 0 -0.001 10 0 0 0 1.64E+07 1.21E+07 - - - 0.1576 0.9887 230117_WJC_METTL3_WT_vs_EV_F07.12607.12607.2 1.89 12-Jun R.GDIQTLK[136.11].N sp|Q9HC62|SENP2_HUMAN 1 781.4425 1.05 56162 12607 2 781.44263 391.7285 Sentrin-specific protease 2 OS=Homo sapiens OX=9606 GN=SENP2 PE=1 SV=3 5.84 2844.3 - 9.23E+06 - - - 0.142 - 1.232 0.122 - 191.1 1 2 0 0.0001 7 0 0 0 7.36E+08 6.99E+08 - - - 0.6031 0.9959 230117_WJC_METTL3_WT_vs_EV_F07.12618.12618.2 0.277 12-Jul R.WLGEPIK.A "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 841.4698 0.45 56166 12618 2 841.470135 421.7422 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6 2845.9 - 5.57E+06 - - - 0.41 - 1.195 0.226 - 255.2 1 2 0 0.0003 7 0 0 0 1.36E+09 3.04E+09 - - - 1.2746 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.12631.12631.2 0.00123 16-Jul R.LYEALTPVH.- "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1041.5495 - 56170 12631 2 1041.552926 521.782 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.24 2847.7 - 293836 - - - 3.2932 - 1.304 0.406 - 116 1 2 0 0.0034 9 0 0 0 - - - - - 2.8066 0.9951 230117_WJC_METTL3_WT_vs_EV_F07.12637.12637.2 0.162 14-Jun K.IPYTTVLR.L "sp|Q08945|SSRP1_HUMAN,tr|E9PMD4|E9PMD4_HUMAN" 2 961.5597 0.27 56172 12637 2 961.561242 481.7871 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 8.75 2848.5 - 335140 - - - 1.638 - 1.239 0.178 - 98.1 1 2 0 0.0016 8 0 0 0 1.36E+08 5.08E+08 - - - 1.0015 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.12645.12645.2 0.0213 12-May R.LVVFDAR[166.11].- sp|P53803|RPAB4_HUMAN 1 828.4733 1.05 56177 12645 2 828.473464 415.2439 "DNA-directed RNA polymerases I, II, and III subunit RPABC4 OS=Homo sapiens OX=9606 GN=POLR2K PE=1 SV=1" 5.84 2849.2 - 6.18E+06 - - - 0.1883 - 1.305 0.365 - 98.7 1 2 0 0.0002 7 0 0 0 4.04E+08 3.84E+08 - - - 2.5803 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.12658.12658.2 0.0319 20-Aug R.TAAENDFVTLK.K sp|P35908|K22E_HUMAN 1 1207.6085 23.12 56180 12658 2 1207.611365 604.8115 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2851.1 - 128777 - - - 2.399 - 1.72 0.321 - 200.6 1 2 0 0.0029 11 0 0 0 6.16E+06 2.66E+05 - - - 2.8781 0.9893 230117_WJC_METTL3_WT_vs_EV_F07.12669.12669.2 0.335 16-Sep K.AGLAPLEVR.V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 924.5393 0.82 56186 12669 2 924.538577 463.2769 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.05 2852.4 - 498027 - - - -0.7452 - 1.615 0.081 - 186.8 1 2 0 -0.0007 9 0 0 0 1.13E+08 1.39E+08 - - - 1.0258 0.9169 230117_WJC_METTL3_WT_vs_EV_F07.12677.12677.2 0.0101 12-Sep L.PLQDVYK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 861.4596 3.37 56189 12677 2 861.460833 431.7371 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.26 2853.4 - 385804 - - - 1.4092 - 1.581 0.238 - 261.6 1 1 0 0.0012 7 0 0 0 2.69E+07 7.99E+06 - - - 2.2499 0.9874 230117_WJC_METTL3_WT_vs_EV_F07.12683.12683.2 0.606 12-Jun R.VPLYTLR.D sp|Q96DE0|NUD16_HUMAN 1 860.512 0.76 56193 12683 2 860.512653 431.2633 U8 snoRNA-decapping enzyme OS=Homo sapiens OX=9606 GN=NUDT16 PE=1 SV=2 8.72 2854.1 - 396722 - - - 0.7716 - 1.202 0.1 - 95.6 1 2 0 0.0007 7 0 0 0 2.21E+07 2.90E+07 - - - 0.3624 0.995 230117_WJC_METTL3_WT_vs_EV_F07.12700.12700.2 0.411 16-Jun K.LVPVGYGIR[166.11].K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 982.5839 0.96 56201 12700 2 982.584896 492.2992 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2856.3 - 7.31E+06 - - - 0.9913 - 1.232 0.182 - 126.2 1 2 0 0.001 9 0 0 0 8.77E+08 9.13E+08 - - - 0.9885 0.9949 230117_WJC_METTL3_WT_vs_EV_F07.12711.12711.2 0.0204 12-Aug R.FAAFIDK.V "sp|Q14533|KRT81_HUMAN,sp|P78386|KRT85_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|U3KPR1|U3KPR1_HUMAN" 6 810.4276 21.69 56206 12711 2 810.427017 406.2211 "Keratin, type II cuticular Hb1 OS=Homo sapiens OX=9606 GN=KRT81 PE=1 SV=3" 5.84 2857.6 - 2.65E+06 - - - -0.707 - 1.767 0.104 - 190.1 1 2 0 -0.0006 7 0 0 0 1.03E+08 4.75E+06 - - - 1.6128 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.12712.12712.2 0.00838 16-Sep K.IGPLGLSPK.K sp|P30050|RL12_HUMAN 1 880.5382 1.65 56207 12712 2 880.538597 441.2764 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2857.7 - 5.55E+06 - - - 0.4475 - 1.631 0.402 - 225.6 1 2 0 0.0004 9 0 0 0 1.58E+10 9.57E+09 - - - 3.4253 0.9431 230117_WJC_METTL3_WT_vs_EV_F07.12719.12719.2 1.12 18-Jul R.QVLDNLTMEK.S "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1189.6013 999 56210 12719 2 1189.60047 595.8079 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.37 2858.6 - 276067 - - - -0.6759 - 1.026 0.095 - 53.4 1 2 0 -0.0008 10 0 0 0 4.27E+06 0.00E+00 - - - -0.1859 0.9934 230117_WJC_METTL3_WT_vs_EV_F07.12723.12723.2 2.16 12-Jul R.LAILYAK.R "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 790.4953 1.2 56212 12723 2 790.495286 396.2549 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 8.59 2859.1 - 1.09E+06 - - - 0.0127 - 1.668 0.053 - 159 1 2 0 0 7 0 0 0 2.89E+08 2.41E+08 - - - 1.0536 0.9374 230117_WJC_METTL3_WT_vs_EV_F07.12727.12727.2 1.91 12-May R.LIELVDR.G sp|Q68D91|MBLC2_HUMAN 1 856.5018 3.44 56215 12727 2 856.500979 429.2582 Acyl-coenzyme A thioesterase MBLAC2 OS=Homo sapiens OX=9606 GN=MBLAC2 PE=1 SV=3 4.37 2859.5 - 924621 - - - -0.9796 - 1.107 0.069 - 56.8 1 2 0 -0.0008 7 0 0 0 6.48E+07 1.89E+07 - - - -0.1275 0.9777 230117_WJC_METTL3_WT_vs_EV_F07.12731.12731.2 1.82 14-Sep R.LGNSLLLK.Y sp|Q10570|CPSF1_HUMAN 1 856.5382 0.04 56217 12731 2 856.537922 429.2764 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 2860 - 1.13E+06 - - - -0.3281 - 1.472 0.014 - 134.9 1 2 0 -0.0003 8 0 0 0 1.39E+08 3.41E+09 - - - 0.3103 0.9519 230117_WJC_METTL3_WT_vs_EV_F07.12736.12736.2 3.42 12-Jun R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 164.94 56220 12736 2 776.381402 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2860.6 - 586172 - - - -0.3877 - 1.128 0.071 - 95.8 2 2 0 -0.0003 7 0 0 0 1.42E+09 8.63E+06 - - - -0.1875 0.9642 230117_WJC_METTL3_WT_vs_EV_F07.12739.12739.2 5.6 16-Jun K.LVPVGYGIR.K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 972.5757 0.96 56222 12739 2 972.575045 487.2951 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2860.9 - 1.27E+07 - - - -0.6241 - 1.12 0.1 - 148.9 1 2 0 -0.0006 9 0 0 0 8.81E+08 9.16E+08 - - - 0.1073 0.9464 230117_WJC_METTL3_WT_vs_EV_F07.12743.12743.2 1.06 12-Jul R.TLQVLIK.Q "sp|Q7Z3B4|NUP54_HUMAN,sp|P35219|CAH8_HUMAN" 2 813.5324 2.46 56224 12743 2 813.531616 407.7735 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.41 2861.4 - 2.86E+06 - - - -0.9514 - 1.258 0.027 - 169.7 1 2 0 -0.0008 7 0 0 0 1.87E+08 7.59E+07 - - - -0.0326 0.9923 230117_WJC_METTL3_WT_vs_EV_F07.12745.12745.2 0.00474 18-Aug R.RVLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1125.687 1.1 56226 12745 2 1125.693199 563.8508 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2861.6 - 488127 - - - 5.5131 - 1.814 0.265 - 172.8 1 2 0 0.0062 10 0 0 0 4.51E+07 4.09E+07 - - - 2.6587 0.9963 230117_WJC_METTL3_WT_vs_EV_F07.12762.12762.2 0.0441 12-Sep K.LTATIWK[136.11].N sp|O15226|NKRF_HUMAN 1 839.4996 1.73 56230 12762 2 839.498497 420.7571 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 8.75 2864 - 1.67E+06 - - - -1.3615 - 1.728 0.208 - 180.8 1 2 0 -0.0011 7 0 0 0 1.19E+08 6.89E+07 - - - 2.31 0.996 230117_WJC_METTL3_WT_vs_EV_F07.12764.12764.2 0.117 12-Jun K.FLEPTLR.L "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 874.4913 1.05 56231 12764 2 874.491007 438.2529 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 2864.3 - 5.32E+06 - - - -0.2813 - 1.306 0.23 - 155.4 1 2 0 -0.0002 7 0 0 0 4.21E+08 4.01E+08 - - - 1.5856 0.9828 230117_WJC_METTL3_WT_vs_EV_F07.12784.12784.2 0.384 20-Jul R.ILILGLDGAGK.T "sp|P40616|ARL1_HUMAN,tr|F8VYN9|F8VYN9_HUMAN,tr|F8VP99|F8VP99_HUMAN,tr|F8VP63|F8VP63_HUMAN" 4 1068.6543 999 56240 12784 2 1068.658715 535.3344 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 5.84 2866.7 - 4.20E+06 - - - 4.1351 - 1.593 0.131 - 103.4 3 2 0 0.0044 11 0 0 0 8.89E+08 0.00E+00 - - - 1.0537 0.9759 230117_WJC_METTL3_WT_vs_EV_F07.12808.12808.2 0.86 12-Jun K.IESLLYR[166.11].L "sp|P42694|HELZ_HUMAN,tr|J3KT20|J3KT20_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN,tr|J3KS59|J3KS59_HUMAN" 5 902.5101 1.88 56249 12808 2 902.510845 452.2623 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 6 2869.7 - 1.21E+06 - - - 0.8388 - 1.415 0.006 - 73.2 4 2 0 0.0008 7 0 0 0 1.34E+08 7.11E+07 - - - -0.084 0.9086 230117_WJC_METTL3_WT_vs_EV_F07.12813.12813.2 0.114 12-Jun R.LVNQWIK.Q "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 899.5229 1.3 56251 12813 2 899.519794 450.7687 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 8.75 2870.4 - 1.93E+06 - - - -3.4396 - 1.085 0.182 - 70.9 1 2 0 -0.0031 7 0 0 0 6.35E+07 4.87E+07 - - - 0.6428 0.9936 230117_WJC_METTL3_WT_vs_EV_F07.12818.12818.2 1.63 12-Aug R.LVNQWIK[136.11].Q "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 907.5371 1.26 56253 12818 2 907.535989 454.7758 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 8.75 2871 - 990241 - - - -1.211 - 1.371 0.223 - 136 1 2 0 -0.0011 7 0 0 0 6.35E+07 5.05E+07 - - - 1.6875 0.9969 230117_WJC_METTL3_WT_vs_EV_F07.12820.12820.2 0.494 14-Aug K.TALLGLTK[136.11].T sp|Q9BTZ2|DHRS4_HUMAN 1 823.5259 0.94 56254 12820 2 823.525547 412.7702 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 8.41 2871.2 - 9.86E+06 - - - -0.3728 - 1.438 0.236 - 236.7 1 2 0 -0.0003 8 0 0 0 9.57E+08 1.02E+09 - - - 1.8796 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.12827.12827.2 0.0188 16-Sep K.IGPLGLSPK[136.11].K sp|P30050|RL12_HUMAN 1 888.5524 1.65 56256 12827 2 888.551359 445.2835 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2872.2 - 1.46E+08 - - - -1.1749 - 1.923 0.238 - 229 1 2 0 -0.001 9 0 0 0 1.58E+10 9.57E+09 - - - 2.6903 0.851 230117_WJC_METTL3_WT_vs_EV_F07.12832.12832.2 0.519 14-Oct D.IADIEALK.E "sp|Q70CQ2|UBP34_HUMAN,sp|O75792|RNH2A_HUMAN,tr|A0A2R8Y606|A0A2R8Y606_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 4 871.5015 1.71 56258 12832 2 871.5007 436.758 Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens OX=9606 GN=USP34 PE=1 SV=2 4.37 2872.8 - 4.99E+06 - - - -0.8996 - 1.844 0.224 - 255.4 1 1 0 -0.0008 8 0 0 0 4.27E+08 2.49E+08 - - - 2.5408 0.9922 230117_WJC_METTL3_WT_vs_EV_F07.12836.12836.2 3.92 14-Sep R.LPVDIAYK.R sp|P15924|DESP_HUMAN 1 917.5222 5.85 56260 12836 2 917.52029 459.7684 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.83 2873.2 - 2.40E+06 - - - -2.1024 - 1.685 0.192 - 285.5 1 2 0 -0.0019 8 0 0 0 3.80E+08 6.49E+07 - - - 2.0321 0.9959 230117_WJC_METTL3_WT_vs_EV_F07.12844.12844.2 0.238 14-Aug K.FGELVMTK[136.11].E "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 931.4928 2.86 56263 12844 2 931.492366 466.7537 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6 2874.3 - 1.19E+06 - - - -0.5089 - 1.407 0.219 - 165.6 1 2 0 -0.0005 8 0 0 0 2.21E+08 7.72E+07 - - - 1.6882 0.9961 230117_WJC_METTL3_WT_vs_EV_F07.12885.12885.2 0.196 12-Jun K.LYALDVR.V "sp|O94913|PCF11_HUMAN,tr|E9PKN0|E9PKN0_HUMAN,tr|E9PQF9|E9PQF9_HUMAN,tr|E9PQ01|E9PQ01_HUMAN" 4 848.4756 0.68 56274 12885 2 848.476045 425.2451 Pre-mRNA cleavage complex 2 protein Pcf11 OS=Homo sapiens OX=9606 GN=PCF11 PE=1 SV=3 5.84 2880.4 - 511775 - - - 0.5209 - 1.306 0.188 - 77 1 2 0 0.0004 7 0 0 0 2.41E+07 3.53E+07 - - - 1.2753 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.12896.12896.3 0.00801 Sep-36 R.LVNHFVEEFK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1260.6503 16.56 56281 12896 3 1260.651601 421.224 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2881.8 - 5.43E+06 - - - 1.0534 - 1.519 0.255 - 103.1 1 2 0 0.0013 10 0 0 0 1.94E+08 1.17E+07 - - - 2.6035 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.12906.12906.2 0.0139 18-Oct R.ISGLIYEETR[166.11].G sp|P62805|H4_HUMAN 1 1189.6218 0.61 56287 12906 2 1189.624522 595.8182 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2883 - 264746 - - - 2.2688 - 2.11 0.361 - 304 1 2 0 0.0027 10 0 0 0 7.56E+06 1.23E+07 - - - 3.7907 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.12907.12907.2 0.000196 18-Dec R.ISGLIYEETR.G sp|P62805|H4_HUMAN 1 1179.6136 0.61 56288 12907 2 1179.614116 590.8141 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2883.1 - 274775 - - - 0.4773 - 2.209 0.374 - 472.3 1 2 0 0.0006 10 0 0 0 7.56E+06 1.23E+07 - - - 4.0154 0.9663 230117_WJC_METTL3_WT_vs_EV_F07.12915.12915.2 0.1 14-Jun R.VIAQLEIR.Q "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|E9PLY5|E9PLY5_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A669KBB0|A0A669KBB0_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A5F9ZGX0|A0A5F9ZGX0_HUMAN" 10 940.5706 6.03 56294 12915 2 940.575775 471.2926 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.97 2884 - 261121 - - - 5.5381 - 1.428 0.174 - 76.2 2 2 0 0.0052 8 0 0 0 6.16E+06 1.02E+06 - - - 1.2646 0.9843 230117_WJC_METTL3_WT_vs_EV_F07.12916.12916.2 0.477 18-Jul R.SISLYYTGEK.G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1159.5761 1.75 56295 12916 2 1159.574664 580.7953 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 5.72 2884.1 - 109106 - - - -1.2427 - 1.002 0.261 - 76.4 1 2 0 -0.0014 10 0 0 0 1.87E+06 1.07E+06 - - - 0.9739 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.12919.12919.2 0.0285 14-Jul K.QVEELFER[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1058.5272 2.64 56296 12919 2 1058.529684 530.2709 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2884.5 - 334961 - - - 2.3514 - 1.631 0.226 - 222.9 1 2 0 0.0025 8 0 0 0 3.18E+07 1.21E+07 - - - 2.1848 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.12926.12926.2 0.0849 18-Aug R.LGPSVVGLAR.Y "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 967.5815 1.44 56301 12926 2 967.58335 484.798 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 9.75 2885.4 - 598002 - - - 1.9482 - 1.65 0.193 - 159.7 1 2 0 0.0019 10 0 0 0 1.03E+08 7.15E+07 - - - 1.8637 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.12928.12928.4 0.000664 15/198 R.SDSPVPTAPTSGGPKPSTASAVPELATDPELEKK.L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3360.6937 999 56303 12928 4 3360.700124 841.1807 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2885.7 - 256397 - - - 1.9231 - 2.77 0.428 - 79.7 1 2 0 0.0065 34 0 0 0 1.15E+07 0.00E+00 - - - 3.2534 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.12937.12937.2 0.0339 20-Sep K.LIADVAPSAIR[166.11].E "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1134.6636 1.44 56308 12937 2 1134.666813 568.3391 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 5.84 2886.9 - 369518 - - - 2.8061 - 1.597 0.293 - 223.9 1 2 0 0.0032 11 0 0 0 3.22E+07 2.23E+07 - - - 2.4705 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.12940.12940.2 0.00398 14-Aug K.FQNALLVR.Y "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 959.5553 999 56310 12940 2 959.557933 480.7849 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 9.75 2887.2 - 235992 - - - 2.7961 - 1.626 0.319 - 199.2 1 2 0 0.0027 8 0 0 0 1.57E+08 0.00E+00 - - - 2.8624 0.9958 230117_WJC_METTL3_WT_vs_EV_F07.12946.12946.2 2.64 16-Oct K.AIPLALEGK[136.11].D "sp|Q9NY93|DDX56_HUMAN,tr|F8WDT8|F8WDT8_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|F8WEI3|F8WEI3_HUMAN" 4 918.563 1.34 56313 12946 2 918.565335 460.2888 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 6.05 2887.9 - 740615 - - - 2.5769 - 1.497 0.161 - 207.9 1 2 0 0.0024 9 0 0 0 3.47E+07 2.59E+07 - - - 1.3966 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.12948.12948.2 0.00858 16-Aug K.IGPLGLSPK.K sp|P30050|RL12_HUMAN 1 880.5382 1.62 56314 12948 2 880.540884 441.2764 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2888.2 - 1.46E+06 - - - 3.0447 - 1.563 0.298 - 157.5 1 2 0 0.0027 9 0 0 0 6.39E+07 3.95E+07 - - - 2.5332 0.9953 230117_WJC_METTL3_WT_vs_EV_F07.12949.12949.2 0.238 12-Jun R.VFLQQLK.G "sp|Q13487|SNPC2_HUMAN,tr|M0QXY9|M0QXY9_HUMAN" 2 874.5276 0.05 56315 12949 2 874.528553 438.2711 snRNA-activating protein complex subunit 2 OS=Homo sapiens OX=9606 GN=SNAPC2 PE=1 SV=1 8.72 2888.3 - 589277 - - - 1.0451 - 1.285 0.163 - 81.4 1 2 0 0.0009 7 0 0 0 1.20E+07 2.64E+08 - - - 1.0392 0.9144 230117_WJC_METTL3_WT_vs_EV_F07.12951.12951.2 2.03 14-Jun K.LISGWVSR.S "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 916.5131 1.38 56317 12951 2 916.518403 459.2638 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 9.75 2888.5 - 997840 - - - 5.8395 - 1.135 0.17 - 78.8 1 2 0 0.0054 8 0 0 0 6.09E+07 4.42E+07 - - - 0.6769 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.12952.12952.2 0.0146 16-Aug K.AFADPEVLR.R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1016.5291 2.47 56318 12952 2 1016.532815 509.2718 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2888.6 - 433035 - - - 3.6595 - 1.522 0.307 - 223.5 1 2 0 0.0037 9 0 0 0 1.05E+08 4.24E+07 - - - 2.5225 0.9894 230117_WJC_METTL3_WT_vs_EV_F07.12962.12962.2 0.322 14-Sep K.LISGWVSR[166.11].S "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 926.5213 2.42 56324 12962 2 926.525346 464.2679 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 9.75 2889.7 - 1.10E+06 - - - 4.3442 - 1.336 0.224 - 172 1 2 0 0.004 8 0 0 0 1.10E+08 4.56E+07 - - - 1.5679 0.994 230117_WJC_METTL3_WT_vs_EV_F07.12963.12963.2 0.198 16-Sep K.AIPLALEGK.D "sp|Q9NY93|DDX56_HUMAN,tr|F8WDT8|F8WDT8_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|F8WEI3|F8WEI3_HUMAN" 4 910.5488 1.29 56325 12963 2 910.551602 456.2817 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 6.05 2889.8 - 657170 - - - 3.1124 - 1.574 0.137 - 254.8 1 2 0 0.0028 9 0 0 0 3.39E+07 2.62E+07 - - - 1.3643 0.9895 230117_WJC_METTL3_WT_vs_EV_F07.12964.12964.2 0.768 14-Jul R.ILLVGEPR.V "sp|Q8IXI2|MIRO1_HUMAN,tr|J3KSR5|J3KSR5_HUMAN" 2 895.5491 1.52 56326 12964 2 895.552177 448.7818 Mitochondrial Rho GTPase 1 OS=Homo sapiens OX=9606 GN=RHOT1 PE=1 SV=2 6 2890 - 604007 - - - 3.4336 - 1.644 0.072 - 158 1 2 0 0.0031 8 0 0 0 2.68E+07 1.77E+07 - - - 1.0712 0.9795 230117_WJC_METTL3_WT_vs_EV_F07.12965.12965.2 1.32 14-Jul R.LVEEELLK[136.11].M sp|Q9BW71|HIRP3_HUMAN 1 979.5681 2.65 56327 12965 2 979.567829 490.7913 HIRA-interacting protein 3 OS=Homo sapiens OX=9606 GN=HIRIP3 PE=1 SV=3 4.25 2890 - 1.14E+06 - - - -0.2899 - 1.155 0.119 - 102.6 1 2 0 -0.0003 8 0 0 0 3.48E+07 1.31E+07 - - - 0.3544 0.9881 230117_WJC_METTL3_WT_vs_EV_F07.12969.12969.2 1.82 14-Aug R.GLGATLLR[166.11].D "sp|Q9H1K4|GHC2_HUMAN,sp|Q9H936|GHC1_HUMAN,tr|A0A0D9SFE1|A0A0D9SFE1_HUMAN,tr|A0A0D9SEI9|A0A0D9SEI9_HUMAN,tr|E9PJH7|E9PJH7_HUMAN,tr|E9PS95|E9PS95_HUMAN" 6 809.4999 8.1 56329 12969 2 809.502708 405.7572 Mitochondrial glutamate carrier 2 OS=Homo sapiens OX=9606 GN=SLC25A18 PE=1 SV=1 9.75 2890.6 - 766387 - - - 3.5207 - 1.521 0.097 - 182 1 2 0 0.0029 8 0 0 0 1.35E+08 1.66E+07 - - - 1.0213 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.12974.12974.2 0.0139 20-Nov K.LIADVAPSAIR.E "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1124.6554 1.43 56333 12974 2 1124.658406 563.335 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 5.84 2891.2 - 1.32E+06 - - - 2.7093 - 2.074 0.31 - 357 1 2 0 0.003 11 0 0 0 3.19E+07 2.23E+07 - - - 3.3031 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.12979.12979.2 0.0016 16-Jul K.AFADPEVLR[166.11].R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1026.5374 2.49 56337 12979 2 1026.540096 514.276 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2891.6 - 748745 - - - 2.6604 - 1.472 0.301 - 182.1 1 2 0 0.0027 9 0 0 0 1.06E+08 4.25E+07 - - - 2.3818 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.12982.12982.2 0.0329 16-Jul R.LVPLVNGVR.E "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 965.6022 2.94 56338 12982 2 965.604078 483.8084 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 9.75 2892 - 2.11E+06 - - - 1.9439 - 1.487 0.277 - 190.2 1 2 0 0.0019 9 0 0 0 1.90E+08 6.45E+07 - - - 2.2342 0.8957 230117_WJC_METTL3_WT_vs_EV_F07.12984.12984.2 2.74 12-Jul R.LLEIVER.Q sp|Q12792|TWF1_HUMAN 1 870.5175 1.25 56340 12984 2 870.522852 436.266 Twinfilin-1 OS=Homo sapiens OX=9606 GN=TWF1 PE=1 SV=3 4.53 2892.2 - 482099 - - - 6.1848 - 1.569 0.03 - 124.9 1 2 0 0.0054 7 0 0 0 5.96E+07 4.75E+07 - - - 0.6881 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.12985.12985.2 2.28E-05 26-Oct R.LVPGGGATEIELAK.Q sp|P50990|TCPQ_HUMAN 1 1353.7504 40.57 56341 12985 2 1353.754949 677.8825 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 2892.4 - 240810 - - - 3.3743 - 1.937 0.479 - 168.8 1 2 0 0.0046 14 0 0 0 4.05E+07 9.99E+05 - - - 4.2366 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.13006.13006.2 0.00744 14-Aug K.GYGFGMVK.L "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RFL1|E5RFL1_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 6 857.4106 1.34 56349 13006 2 857.411272 429.7126 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 8.59 2895.2 - 713862 - - - 0.8304 - 1.195 0.424 - 146.5 1 2 0 0.0007 8 0 0 0 3.44E+07 2.58E+07 - - - 2.7097 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.13015.13015.2 0.0125 18-Aug R.LGLMPPPEPK.V sp|O43395|PRPF3_HUMAN 1 1077.5893 3.68 56353 13015 2 1077.593249 539.8019 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6 2896.4 - 163638 - - - 3.7083 - 1.767 0.259 - 168.6 1 2 0 0.004 10 0 0 0 2.28E+07 6.20E+06 - - - 2.5418 0.9707 230117_WJC_METTL3_WT_vs_EV_F07.13022.13022.2 2.9 12-Jul K.TVYSILR[166.11].H "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 860.4995 0.64 56355 13022 2 860.500738 431.257 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 8.41 2897.3 - 1.44E+06 - - - 1.412 - 1.01 0.092 - 195.7 1 2 0 0.0012 7 0 0 0 2.13E+08 3.31E+08 - - - -0.2483 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.13023.13023.2 0.0719 14-Jul K.GYGFGMVK[136.11].L "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RFL1|E5RFL1_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 6 865.4248 1.34 56356 13023 2 865.425316 433.7197 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 8.59 2897.4 - 737249 - - - 0.6425 - 1.165 0.363 - 67.4 1 2 0 0.0006 8 0 0 0 3.44E+07 2.56E+07 - - - 2.1825 0.9957 230117_WJC_METTL3_WT_vs_EV_F07.13028.13028.2 0.509 12-Jul R.VAIFIEK.T sp|Q9P258|RCC2_HUMAN 1 818.4902 1.58 56358 13028 2 818.490216 410.2524 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2898.1 - 1.62E+06 - - - 0.0305 - 1.38 0.18 - 156.5 1 2 0 0 7 0 0 0 9.47E+07 6.00E+07 - - - 1.391 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.13029.13029.2 0.945 12-Jun K.ELVTLYR.R sp|Q8TD55|PKHO2_HUMAN 1 892.5018 1.04 56359 13029 2 892.503139 447.2582 Pleckstrin homology domain-containing family O member 2 OS=Homo sapiens OX=9606 GN=PLEKHO2 PE=1 SV=1 6.1 2898.3 - 901888 - - - 1.4801 - 1.332 0.182 - 166.4 1 2 0 0.0013 7 0 0 0 4.16E+07 3.99E+07 - - - 1.2932 0.9343 230117_WJC_METTL3_WT_vs_EV_F07.13033.13033.2 0.0312 16-Aug K.MLVVGGIDR.V sp|Q15046|SYK_HUMAN 1 958.527 1.16 56361 13033 2 958.520286 480.2708 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2898.8 - 2.95E+06 - - - -6.9909 - 1.635 0.333 - 291.8 1 2 0 -0.0067 9 0 0 0 1.84E+08 1.58E+08 - - - 2.9208 0.997 230117_WJC_METTL3_WT_vs_EV_F07.13037.13037.2 0.382 12-Aug R.VAIFIEK[136.11].T sp|Q9P258|RCC2_HUMAN 1 826.5044 1.62 56363 13037 2 826.503683 414.2595 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2899.2 - 1.47E+06 - - - -0.8566 - 1.987 0.133 - 240.1 1 2 0 -0.0007 7 0 0 0 9.47E+07 5.86E+07 - - - 2.1987 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.13039.13039.2 0.0362 16-Aug K.MLVVGGIDR[166.11].V sp|Q15046|SYK_HUMAN 1 968.5353 1.16 56364 13039 2 968.534853 485.2749 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2899.4 - 3.22E+06 - - - -0.4171 - 1.739 0.318 - 269.2 1 2 0 -0.0004 9 0 0 0 1.83E+08 1.58E+08 - - - 2.9904 0.9759 230117_WJC_METTL3_WT_vs_EV_F07.13050.13050.2 0.743 14-Aug R.ALEGLVYR.S "sp|Q9Y4R8|TELO2_HUMAN,tr|H3BU45|H3BU45_HUMAN" 2 919.5127 2.96 56367 13050 2 919.50999 460.7636 Telomere length regulation protein TEL2 homolog OS=Homo sapiens OX=9606 GN=TELO2 PE=1 SV=2 6.05 2900.9 - 799503 - - - -2.9657 - 1.391 0.197 - 211.3 1 2 0 -0.0027 8 0 0 0 5.58E+07 1.88E+07 - - - 1.4905 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.13051.13051.2 0.601 12-Jul K.ILEVDLK[136.11].N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 836.5099 0.97 56368 13051 2 836.51005 419.2622 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2901.1 - 877217 - - - 0.2152 - 1.62 0.093 - 128.3 1 2 0 0.0002 7 0 0 0 1.60E+08 1.65E+08 - - - 1.2564 0.9826 230117_WJC_METTL3_WT_vs_EV_F07.13057.13057.2 0.705 14-Aug K.LALLEEAR.T "sp|Q5TZA2|CROCC_HUMAN,sp|P15311|EZRI_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|B1AKD8|B1AKD8_HUMAN" 4 913.5233 1.36 56369 13057 2 913.526378 457.7689 Rootletin OS=Homo sapiens OX=9606 GN=CROCC PE=1 SV=1 4.53 2902 - 1.41E+06 - - - 3.3891 - 1.472 0.106 - 98.5 5 2 0 0.0031 8 0 0 0 4.87E+07 3.58E+07 - - - 0.6767 0.9735 230117_WJC_METTL3_WT_vs_EV_F07.13063.13063.2 4.01 12-May R.QVAIVFR.T "sp|Q04206|TF65_HUMAN,tr|A0A087X0W8|A0A087X0W8_HUMAN,tr|E9PKH5|E9PKH5_HUMAN,tr|Q2TAM5|Q2TAM5_HUMAN" 4 831.4967 3.53 56372 13063 2 831.496346 416.7556 Transcription factor p65 OS=Homo sapiens OX=9606 GN=RELA PE=1 SV=2 9.75 2902.7 - 1.92E+06 - - - -0.3933 - 1.103 0.146 - 93.4 3 2 0 -0.0003 7 0 0 0 1.02E+08 2.90E+07 - - - 0.2167 0.9953 230117_WJC_METTL3_WT_vs_EV_F07.13077.13077.2 0.568 12-Aug K.ILEVDLK.N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 828.4957 0.8 56379 13077 2 828.496425 415.2551 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2904.5 - 2.49E+06 - - - 0.9113 - 1.646 0.058 - 174.2 1 2 0 0.0008 7 0 0 0 1.31E+08 1.65E+08 - - - 1.0482 0.9951 230117_WJC_METTL3_WT_vs_EV_F07.13090.13090.2 0.203 12-Jul R.IFVDIEK[136.11].L "sp|P06737|PYGL_HUMAN,tr|E9PK47|E9PK47_HUMAN" 2 870.4942 4.61 56386 13090 2 870.494809 436.2544 "Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL PE=1 SV=4" 4.37 2906.1 - 514317 - - - 0.6766 - 1.247 0.18 - 100.1 1 2 0 0.0006 7 0 0 0 6.60E+07 1.43E+07 - - - 1.0697 0.9617 230117_WJC_METTL3_WT_vs_EV_F07.13097.13097.2 2.44 12-Jun R.LSSFIVK.E sp|P24278|ZBT25_HUMAN 1 792.4745 0.84 56388 13097 2 792.473781 397.2445 Zinc finger and BTB domain-containing protein 25 OS=Homo sapiens OX=9606 GN=ZBTB25 PE=1 SV=2 8.75 2907.1 - 1.44E+06 - - - -0.959 - 1.281 0.093 - 77.1 5 2 0 -0.0008 7 0 0 0 6.58E+07 7.81E+07 - - - 0.2001 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.13107.13107.2 0.319 14-Jun R.QMAAVLLR[166.11].R "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 11 910.5298 1.12 56393 13107 2 910.530057 456.2722 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 2908.4 - 1.09E+06 - - - 0.3064 - 1.435 0.174 - 146.9 1 2 0 0.0003 8 0 0 0 7.61E+07 6.80E+07 - - - 1.4153 0.996 230117_WJC_METTL3_WT_vs_EV_F07.13120.13120.2 0.0856 14-Jul K.LTPVLLAK[136.11].Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 861.5779 1.79 56402 13120 2 861.577517 431.7962 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2910 - 4.99E+06 - - - -0.4329 - 1.3 0.249 - 141.8 1 2 0 -0.0004 8 0 0 0 4.16E+08 2.33E+08 - - - 1.6713 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.13126.13126.2 0.0135 14-Sep K.VVLVLAGR[166.11].Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 835.5519 0.77 56406 13126 2 835.554078 418.7832 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2910.7 - 4.55E+06 - - - 2.615 - 1.779 0.32 - 281.2 1 2 0 0.0022 8 0 0 0 2.28E+09 2.95E+09 - - - 3.1412 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.13128.13128.2 0.0136 14-Sep K.VVLVLAGR.Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 825.5436 0.77 56407 13128 2 825.545267 413.7791 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2910.9 - 2.94E+06 - - - 1.9914 - 1.632 0.372 - 389.5 1 2 0 0.0016 8 0 0 0 2.28E+09 2.95E+09 - - - 3.2653 0.9961 230117_WJC_METTL3_WT_vs_EV_F07.13132.13132.2 0.269 12-Aug R.FASFIER.V sp|P07196|NFL_HUMAN 1 868.4443 1.95 56410 13132 2 868.443186 435.2294 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2911.4 - 1.02E+06 - - - -1.2862 - 1.668 0.208 - 197.6 1 2 0 -0.0011 7 0 0 0 1.44E+08 7.37E+07 - - - 2.1981 0.9786 230117_WJC_METTL3_WT_vs_EV_F07.13144.13144.2 0.121 12-Jul R.FASFIER[166.11].V sp|P07196|NFL_HUMAN 1 878.4526 1.91 56415 13144 2 878.456375 440.2336 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2913 - 1.91E+06 - - - 4.3281 - 1.454 0.103 - 164.8 1 2 0 0.0038 7 0 0 0 1.41E+08 7.37E+07 - - - 0.9866 0.9965 230117_WJC_METTL3_WT_vs_EV_F07.13150.13150.2 0.373 14-Jun K.LTPVLLAK.Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 853.5637 1.79 56418 13150 2 853.56454 427.7891 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2913.8 - 1.13E+07 - - - 0.9958 - 1.01 0.298 - 89.8 1 2 0 0.0008 8 0 0 0 4.16E+08 2.33E+08 - - - 1.2718 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.13171.13171.2 0.0342 14-May R.IFNTFGPR[166.11].M "sp|Q8NBZ7|UXS1_HUMAN,tr|C9JCB7|C9JCB7_HUMAN,tr|C9JFU6|C9JFU6_HUMAN,tr|C9JE50|C9JE50_HUMAN" 4 960.5057 0.84 56431 13171 2 960.50761 481.2601 UDP-glucuronic acid decarboxylase 1 OS=Homo sapiens OX=9606 GN=UXS1 PE=1 SV=1 9.75 2916.3 - 441594 - - - 2.0187 - 1.367 0.281 - 53.9 1 2 0 0.0019 8 0 0 0 4.67E+07 5.55E+07 - - - 2.0587 0.998 230117_WJC_METTL3_WT_vs_EV_F07.13175.13175.2 0.15 12-Jun K.ILMEFNK.M sp|Q9UQE7|SMC3_HUMAN 1 893.4681 1.68 56433 13175 2 893.468775 447.7413 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2916.8 - 569901 - - - 0.7835 - 1.187 0.295 - 74.4 1 2 0 0.0007 7 0 0 0 7.92E+07 4.72E+07 - - - 1.7628 0.999 230117_WJC_METTL3_WT_vs_EV_F07.13184.13184.2 0.423 14-Sep K.IADFGLAR.L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 861.4709 2.94 56438 13184 2 861.471948 431.7427 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2917.8 - 2.88E+06 - - - 1.2722 - 1.732 0.224 - 199.5 1 2 0 0.0011 8 0 0 0 1.54E+08 5.24E+07 - - - 2.3517 0.9924 230117_WJC_METTL3_WT_vs_EV_F07.13185.13185.2 0.264 14-Jul R.IFNTFGPR.M "sp|Q8NBZ7|UXS1_HUMAN,tr|C9JCB7|C9JCB7_HUMAN,tr|C9JFU6|C9JFU6_HUMAN,tr|C9JE50|C9JE50_HUMAN" 4 950.4974 0.85 56439 13185 2 950.499098 476.256 UDP-glucuronic acid decarboxylase 1 OS=Homo sapiens OX=9606 GN=UXS1 PE=1 SV=1 9.75 2917.9 - 957823 - - - 1.7854 - 1.272 0.127 - 111.4 1 2 0 0.0017 8 0 0 0 4.60E+07 5.39E+07 - - - 0.7041 0.9897 230117_WJC_METTL3_WT_vs_EV_F07.13189.13189.2 3.64 12-Jul R.LISSLLR.T "sp|Q9BQ52|RNZ2_HUMAN,sp|Q8NCN5|PDPR_HUMAN,sp|Q96P20|NLRP3_HUMAN,sp|Q96MN2|NALP4_HUMAN,sp|Q8NGV5|O13D1_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|A0A7I2PMC6|A0A7I2PMC6_HUMAN,tr|E7ES68|E7ES68_HUMAN,tr|A0A2R8YEG7|A0A2R8YEG7_HUMAN,tr|A8MT40|A8MT40_HUMAN,tr|A0A7I2PJH0|A0A7I2PJH0_HUMAN,tr|H3BQG3|H3BQG3_HUMAN,tr|A0A7I2PRX0|A0A7I2PRX0_HUMAN,tr|A0A7I2YME5|A0A7I2YME5_HUMAN,tr|A0A286YF94|A0A286YF94_HUMAN,tr|A0A7I2UNQ2|A0A7I2UNQ2_HUMAN,tr|A0A7I2R3P8|A0A7I2R3P8_HUMAN" 17 800.512 1.83 56441 13189 2 800.513935 401.2633 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 9.75 2918.4 - 826644 - - - 2.4309 - 1.495 0.046 - 146.9 1 2 0 0.0019 7 0 0 0 3.09E+07 1.68E+07 - - - 0.6543 0.9902 230117_WJC_METTL3_WT_vs_EV_F07.13190.13190.2 1.14 12-Jul R.VNLLAVR.D "sp|Q9H4H8|FA83D_HUMAN,tr|A0A087WXK8|A0A087WXK8_HUMAN" 2 783.4967 2.03 56442 13190 2 783.499108 392.7556 Protein FAM83D OS=Homo sapiens OX=9606 GN=FAM83D PE=1 SV=3 9.72 2918.5 - 760884 - - - 3.1079 - 1.585 0.064 - 137.2 1 2 0 0.0024 7 0 0 0 2.44E+07 1.20E+07 - - - 0.9723 0.9912 230117_WJC_METTL3_WT_vs_EV_F07.13194.13194.2 0.811 14-May R.LFAAELGR.E "sp|O00255|MEN1_HUMAN,tr|A0A5F9ZHS3|A0A5F9ZHS3_HUMAN,tr|E7EN32|E7EN32_HUMAN,tr|Q9GZQ5|Q9GZQ5_HUMAN,tr|E7ENS2|E7ENS2_HUMAN" 5 875.4865 1.43 56444 13194 2 875.488255 438.7505 Menin OS=Homo sapiens OX=9606 GN=MEN1 PE=1 SV=4 6 2919.1 - 2.20E+06 - - - 2.0023 - 1.352 0.18 - 41 28 2 0 0.0018 8 0 0 0 7.27E+07 5.09E+07 - - - 0.633 0.9959 230117_WJC_METTL3_WT_vs_EV_F07.13196.13196.2 0.317 14-Jul K.LLAEVTLK.T "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 4 885.5535 2.5 56445 13196 2 885.554557 443.784 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 6 2919.3 - 1.78E+06 - - - 1.1721 - 1.221 0.202 - 114.7 1 2 0 0.001 8 0 0 0 1.27E+08 5.07E+07 - - - 1.1348 0.9899 230117_WJC_METTL3_WT_vs_EV_F07.13202.13202.2 0.929 12-Jun K.ILMEFNK[136.11].M sp|Q9UQE7|SMC3_HUMAN 1 901.4823 1.73 56447 13202 2 901.483848 451.7484 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2920.1 - 917158 - - - 1.7449 - 1.171 0.129 - 78.8 1 2 0 0.0016 7 0 0 0 8.02E+07 4.64E+07 - - - 0.4935 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.13228.13228.2 0.056 14-Jul K.IGDFGLAR.D "sp|P08922|ROS1_HUMAN,sp|P07333|CSF1R_HUMAN,sp|P51617|IRAK1_HUMAN,sp|Q96PY6|NEK1_HUMAN,sp|P51955|NEK2_HUMAN,sp|Q6P3R8|NEK5_HUMAN,sp|Q16659|MK06_HUMAN,sp|P31152|MK04_HUMAN,tr|E9PIX7|E9PIX7_HUMAN,tr|H7C2I6|H7C2I6_HUMAN,tr|K7EN18|K7EN18_HUMAN,tr|A0A494C168|A0A494C168_HUMAN,tr|F6U4U2|F6U4U2_HUMAN,tr|H7C224|H7C224_HUMAN,tr|K7ELV1|K7ELV1_HUMAN,tr|Q5H8Y1|Q5H8Y1_HUMAN,tr|A0A3B3ITQ6|A0A3B3ITQ6_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 18 847.4552 2.36 56459 13228 2 847.455494 424.7349 Proto-oncogene tyrosine-protein kinase ROS OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3 5.84 2923.5 - 3.08E+06 - - - 0.3446 - 1.822 0.135 - 129.6 1 2 0 0.0003 8 0 0 0 9.43E+07 3.99E+07 - - - 1.8474 0.9918 230117_WJC_METTL3_WT_vs_EV_F07.13230.13230.2 0.662 14-Jul R.NVVYPLYR.L "sp|Q16540|RM23_HUMAN,tr|A8MYK1|A8MYK1_HUMAN,tr|A8MVT4|A8MVT4_HUMAN,tr|A6NJD9|A6NJD9_HUMAN" 4 1022.5549 999 56461 13230 2 1022.556741 512.2847 "39S ribosomal protein L23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL23 PE=1 SV=1" 8.59 2923.6 - 1.21E+06 - - - 1.7847 - 1.296 0.111 - 182.3 1 2 0 0.0018 8 0 0 0 3.85E+07 0.00E+00 - - - 0.6423 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.13232.13232.2 0.726 14-Aug K.LALDYGIK[136.11].F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 899.5208 1.25 56463 13232 2 899.522621 450.7677 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 2923.8 - 912292 - - - 2.0589 - 1.725 0.205 - 132.2 1 2 0 0.0019 8 0 0 0 2.59E+07 2.07E+07 - - - 2.1989 0.9956 230117_WJC_METTL3_WT_vs_EV_F07.13236.13236.2 1.25 12-Aug R.LALEELR.S sp|Q99496|RING2_HUMAN 1 842.4862 1.05 56465 13236 2 842.486107 422.2504 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.53 2924.3 - 1.50E+06 - - - -0.0724 - 1.67 0.102 - 203.9 1 2 0 -0.0001 7 0 0 0 3.14E+08 2.99E+08 - - - 1.4193 0.8967 230117_WJC_METTL3_WT_vs_EV_F07.13245.13245.2 0.00978 16-Jul K.LVRPPVQVY.G "sp|P48047|ATPO_HUMAN,tr|H7C086|H7C086_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 4 1069.6284 1.83 56470 13245 2 1069.628773 535.8215 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.75 2925.4 - 631567 - - - 0.3347 - 1.247 0.346 - 75 1 1 0 0.0004 9 0 0 0 2.33E+07 1.27E+07 - - - 2.2351 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.13251.13251.2 0.00249 20-Aug K.YGQISEVVVVK[136.11].D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1227.6954 1.05 56474 13251 2 1227.697889 614.855 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2926.2 - 315945 - - - 1.9956 - 1.629 0.382 - 170 1 2 0 0.0024 11 0 0 0 4.37E+06 4.15E+06 - - - 3.1817 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.13260.13260.2 0.0107 14-Jun K.VLPITVPK.S sp|Q9ULW0|TPX2_HUMAN 1 865.5637 2.06 56479 13260 2 865.563836 433.7891 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.72 2927.3 - 1.19E+06 - - - 0.1687 - 1.335 0.365 - 86.7 1 2 0 0.0001 8 0 0 0 6.59E+07 3.20E+07 - - - 2.6082 0.9895 230117_WJC_METTL3_WT_vs_EV_F07.13262.13262.2 2.43 14-May K.VLPITVPK[136.11].S sp|Q9ULW0|TPX2_HUMAN 1 873.5779 2.06 56481 13262 2 873.579212 437.7962 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.72 2927.5 - 622894 - - - 1.5133 - 0.89 0.284 - 36.1 6 2 0 0.0013 8 0 0 0 6.59E+07 3.20E+07 - - - 0.4391 0.9832 230117_WJC_METTL3_WT_vs_EV_F07.13263.13263.2 0.223 14-Sep K.INELLLAK.E "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 912.5644 1.95 56482 13263 2 912.568967 457.2895 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 6 2927.6 - 440444 - - - 4.9849 - 1.322 0.225 - 150.8 1 2 0 0.0045 8 0 0 0 4.81E+07 2.47E+07 - - - 1.5433 0.9592 230117_WJC_METTL3_WT_vs_EV_F07.13269.13269.2 0.00207 14-Sep E.ILNPLVSK.A "sp|Q6NUP7|PP4R4_HUMAN,sp|Q9BSC4|NOL10_HUMAN,tr|G3V431|G3V431_HUMAN" 3 882.5539 1.11 56486 13269 2 882.554984 442.2842 Serine\threonine-protein phosphatase 4 regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PPP4R4 PE=1 SV=1 8.75 2928.3 - 2.83E+06 - - - 1.2804 - 1.566 0.37 - 196.1 1 1 0 0.0011 8 0 0 0 1.09E+08 9.86E+07 - - - 3.1262 0.999 230117_WJC_METTL3_WT_vs_EV_F07.13273.13273.2 0.0804 16-Jun R.EQVNDLFSR.K "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1106.5356 0.53 56490 13273 2 1106.537156 554.2751 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 2928.8 - 185902 - - - 1.3728 - 1.523 0.295 - 100.4 1 2 0 0.0015 9 0 0 0 5.83E+06 1.09E+07 - - - 2.4364 0.973 230117_WJC_METTL3_WT_vs_EV_F07.13279.13279.2 0.516 14-Aug K.LIGQLNLK.D "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 897.5648 1.35 56494 13279 2 897.565826 449.7897 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 2929.5 - 599105 - - - 1.1955 - 1.286 0.001 - 107 1 2 0 0.0011 8 0 0 0 1.73E+07 1.28E+07 - - - -0.1933 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.13283.13283.2 0.0455 14-Aug K.VVNPLFEK[136.11].R "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 952.5473 0.84 56496 13283 2 952.548011 477.2809 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.97 2930 - 1.35E+06 - - - 0.7275 - 1.533 0.21 - 163 1 2 0 0.0007 8 0 0 0 1.23E+08 1.46E+08 - - - 1.8803 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.13291.13291.2 0.00463 14-Aug K.VVNPLFEK.R "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 944.5331 0.88 56502 13291 2 944.531919 473.2738 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.97 2930.9 - 1.28E+06 - - - -1.2694 - 1.589 0.351 - 174.8 1 2 0 -0.0012 8 0 0 0 1.30E+08 1.47E+08 - - - 3.0298 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.13295.13295.2 0.212 14-Oct K.INELLLAK[136.11].E "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 920.5786 2.62 56504 13295 2 920.580444 461.2966 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 6 2931.3 - 1.22E+06 - - - 1.9835 - 1.785 0.206 - 201.1 2 2 0 0.0018 8 0 0 0 6.59E+07 2.52E+07 - - - 2.175 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.13298.13298.2 0.0769 14-Aug K.VLTISTLR.L "sp|Q12830|BPTF_HUMAN,tr|F5GXF5|F5GXF5_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN,tr|A0A0A0MR81|A0A0A0MR81_HUMAN" 6 901.5597 0.57 56506 13298 2 901.562011 451.7871 Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3 9.72 2931.6 - 608653 - - - 2.5999 - 1.469 0.287 - 183.1 1 2 0 0.0023 8 0 0 0 1.37E+07 2.39E+07 - - - 2.3199 0.9957 230117_WJC_METTL3_WT_vs_EV_F07.13315.13315.2 0.194 14-Sep K.ALELTGLK[136.11].V "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 851.5208 0.57 56517 13315 2 851.521676 426.7677 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6.05 2933.8 - 6.73E+06 - - - 1.0652 - 1.682 0.067 - 230.7 1 2 0 0.0009 8 0 0 0 1.25E+08 2.18E+08 - - - 1.1038 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.13326.13326.2 0.468 12-Jul R.NLPMHLR.R "sp|Q9P2E3|ZNFX1_HUMAN,tr|Q5JXR6|Q5JXR6_HUMAN,tr|Q5JXR7|Q5JXR7_HUMAN,tr|Q5JXR5|Q5JXR5_HUMAN" 4 879.4749 401.57 56526 13326 2 879.475436 440.7447 NFX1-type zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=ZNFX1 PE=2 SV=2 9.76 2935.1 - 4.77E+06 - - - 0.6186 - 1.526 0.178 - 203.4 1 2 0 0.0005 7 0 0 0 2.31E+08 5.76E+05 - - - 1.6947 0.9678 230117_WJC_METTL3_WT_vs_EV_F07.13327.13327.2 9.15 14-May R.LFVGSIPK.S "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 859.5167 0.9 56527 13327 2 859.517717 430.7656 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.75 2935.2 - 4.16E+06 - - - 1.1367 - 1.098 0.079 - 85.6 3 2 0 0.001 8 0 0 0 1.85E+09 2.04E+09 - - - -0.307 0.998 230117_WJC_METTL3_WT_vs_EV_F07.13330.13330.2 0.000929 14-Sep -.MFAPAVMR[166.11].A sp|Q9P0S2|COX16_HUMAN 1 931.4647 1.54 56530 13330 2 931.464913 466.7396 "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COX16 PE=1 SV=1" 9.5 2935.5 - 407353 - - - 0.1922 - 1.692 0.181 - 250.8 1 2 0 0.0002 8 0 0 0 5.43E+07 3.53E+07 - - - 1.9639 0.9 230117_WJC_METTL3_WT_vs_EV_F07.13332.13332.2 2.88 14-May R.TSADVEIR.G "sp|Q6ZRS2|SRCAP_HUMAN,tr|A0A0C4DFX4|A0A0C4DFX4_HUMAN,tr|A0A0A0MS59|A0A0A0MS59_HUMAN" 3 889.4505 44.11 56531 13332 2 889.451068 445.7325 Helicase SRCAP OS=Homo sapiens OX=9606 GN=SRCAP PE=1 SV=3 4.37 2935.7 - 2.75E+06 - - - 0.6262 - 1.074 0.004 - 84.4 4 2 0 0.0006 8 0 0 0 8.53E+07 1.93E+06 - - - -0.9833 0.9924 230117_WJC_METTL3_WT_vs_EV_F07.13334.13334.2 0.367 12-Aug K.TIADIIR.T "sp|P49368|TCPG_HUMAN,sp|Q16878|CDO1_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 800.4756 9.82 56532 13334 2 800.476385 401.2451 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.5 2935.9 - 3.22E+06 - - - 0.9769 - 1.336 0.099 - 234.8 1 2 0 0.0008 7 0 0 0 2.75E+09 2.80E+08 - - - 0.6898 0.9071 230117_WJC_METTL3_WT_vs_EV_F07.13340.13340.2 22.5 12-May K.FIPLYSK[136.11].V "sp|Q14694|UBP10_HUMAN,tr|J3KT19|J3KT19_HUMAN,tr|H3BVF1|H3BVF1_HUMAN" 3 874.5044 1.21 56536 13340 2 874.504458 438.2595 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.59 2936.5 - 517518 - - - 0.0766 - 0.95 0.063 - 60.3 2 2 0 0.0001 7 0 0 0 1.46E+08 1.21E+08 - - - -0.7907 0.9407 230117_WJC_METTL3_WT_vs_EV_F07.13341.13341.2 1.7 12-May R.GFLAEMK.R "sp|A6ZKI3|RTL8C_HUMAN,sp|Q9BWD3|RTL8A_HUMAN,sp|Q17RB0|RTL8B_HUMAN" 3 794.3997 1.16 56537 13341 2 794.399961 398.2071 Retrotransposon Gag-like protein 8C OS=Homo sapiens OX=9606 GN=RTL8C PE=1 SV=1 6 2936.6 - 369082 - - - 0.3776 - 0.936 0.098 - 55 2 2 0 0.0003 7 0 0 0 3.51E+07 3.03E+07 - - - -0.5793 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.13342.13342.2 0.000712 12-Jul K.YGVDLIR.Y sp|Q6UXN9|WDR82_HUMAN 1 834.46 2.61 56538 13342 2 834.461113 418.2373 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 5.84 2936.6 - 872668 - - - 1.3901 - 1.428 0.154 - 170.6 1 2 0 0.0012 7 0 0 0 2.87E+08 1.10E+08 - - - 1.307 0.9841 230117_WJC_METTL3_WT_vs_EV_F07.13345.13345.2 1.7 22-Jun R.LLLGPAGGGVPK[136.11].L sp|Q96SL8|FIZ1_HUMAN 1 1085.6688 1.34 56541 13345 2 1085.670671 543.8417 Flt3-interacting zinc finger protein 1 OS=Homo sapiens OX=9606 GN=FIZ1 PE=1 SV=2 8.75 2937 - 220006 - - - 1.6957 - 1.245 0.13 - 47.8 8 2 0 0.0018 12 0 0 0 1.29E+07 9.68E+06 - - - 0.1738 0.9484 230117_WJC_METTL3_WT_vs_EV_F07.13348.13348.2 0.973 12-May R.IGLLDPR[166.11].W "sp|Q15459|SF3A1_HUMAN,tr|H7C1L2|H7C1L2_HUMAN" 2 792.4733 1.29 56542 13348 2 792.471932 397.2439 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 5.84 2937.4 - 639091 - - - -1.7363 - 1.135 0.138 - 61.1 2 2 0 -0.0014 7 0 0 0 4.07E+08 3.15E+08 - - - 0.3266 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.13355.13355.2 0.0324 14-Aug R.IFTNLYGR.H "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 4 982.5236 1.03 56547 13355 2 982.525988 492.2691 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.75 2938.3 - 768252 - - - 2.4142 - 1.481 0.293 - 194.5 1 2 0 0.0024 8 0 0 0 7.64E+07 7.38E+07 - - - 2.3888 0.8924 230117_WJC_METTL3_WT_vs_EV_F07.13366.13366.2 1.61 22-May R.LLLGPAGGGVPK.L sp|Q96SL8|FIZ1_HUMAN 1 1077.6546 1.34 56551 13366 2 1077.653555 539.8346 Flt3-interacting zinc finger protein 1 OS=Homo sapiens OX=9606 GN=FIZ1 PE=1 SV=2 8.75 2939.8 - 346506 - - - -0.9975 - 1.231 0.062 - 44.9 16 2 0 -0.0011 12 0 0 0 1.29E+07 9.68E+06 - - - -0.4925 0.9414 230117_WJC_METTL3_WT_vs_EV_F07.13373.13373.2 1.78 12-Jun K.MLGGVFK[136.11].L "sp|Q96MU7|YTDC1_HUMAN,tr|J3QR07|J3QR07_HUMAN" 2 758.424 0.001 56556 13373 2 758.424916 380.2193 YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3 8.5 2940.5 - 1.06E+06 - - - 1.1656 - 0.929 0.096 - 97.8 3 2 0 0.0009 7 0 0 0 0.00E+00 4.21E+07 - - - -0.6967 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.13376.13376.2 0.0103 12-Jul K.YGVDLIR[166.11].Y sp|Q6UXN9|WDR82_HUMAN 1 844.4682 2.76 56557 13376 2 844.469427 423.2414 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 5.84 2940.9 - 2.56E+06 - - - 1.4257 - 1.504 0.331 - 197.4 1 2 0 0.0012 7 0 0 0 2.59E+08 9.36E+07 - - - 2.7786 0.9835 230117_WJC_METTL3_WT_vs_EV_F07.13377.13377.2 5.74 12-Aug K.SVIISIK[136.11].G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 766.5044 1.2 56558 13377 2 766.504648 384.2595 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2941.1 - 1.41E+06 - - - 0.3353 - 1.174 0.099 - 233.8 1 2 0 0.0003 7 0 0 0 2.40E+08 2.00E+08 - - - 0.2804 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.13378.13378.2 0.0263 14-Aug R.LLAAFEER.E "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 947.5076 1.33 56559 13378 2 947.508402 474.7611 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.53 2941.1 - 2.78E+06 - - - 0.8127 - 1.638 0.249 - 193.2 1 2 0 0.0008 8 0 0 0 2.02E+08 1.52E+08 - - - 2.3682 0.994 230117_WJC_METTL3_WT_vs_EV_F07.13382.13382.2 0.298 12-Jul K.SVIISIK.G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 758.4902 1.2 56561 13382 2 758.490677 380.2524 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2941.6 - 1.88E+06 - - - 0.6407 - 1.2 0.176 - 194.1 1 2 0 0.0005 7 0 0 0 2.40E+08 2.00E+08 - - - 0.9185 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.13384.13384.2 0.0186 14-Aug R.LLAAFEER[166.11].E "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 957.5159 1.33 56562 13384 2 957.51689 479.7652 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.53 2941.8 - 2.68E+06 - - - 1.0318 - 1.548 0.267 - 217.9 1 2 0 0.001 8 0 0 0 2.02E+08 1.52E+08 - - - 2.3306 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.13391.13391.2 0.00124 16-Aug R.EMGVIAAMR.D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 976.4834 2.29 56566 13391 2 976.484167 489.249 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 6.1 2942.7 - 395763 - - - 0.7783 - 1.674 0.362 - 168.8 1 2 0 0.0008 9 0 0 0 2.45E+07 1.07E+07 - - - 3.205 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.13397.13397.2 0.043 14-Jul K.LVVWAADR.Q "sp|Q96RQ3|MCCA_HUMAN,tr|G5E9X5|G5E9X5_HUMAN,tr|E9PG35|E9PG35_HUMAN,tr|E9PHF7|E9PHF7_HUMAN,tr|F5GYT8|F5GYT8_HUMAN" 5 928.5131 1.71 56568 13397 2 928.513037 465.2638 "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC1 PE=1 SV=3" 5.84 2943.5 - 754499 - - - -0.0151 - 1.576 0.266 - 152.7 1 2 0 0 8 0 0 0 3.41E+07 1.99E+07 - - - 2.3776 0.9627 230117_WJC_METTL3_WT_vs_EV_F07.13408.13408.2 0.816 14-Jun K.NLILAGVK.G "sp|Q9UBE0|SAE1_HUMAN,tr|B3KNJ4|B3KNJ4_HUMAN,tr|M0QZS6|M0QZS6_HUMAN,tr|A0A590UKC5|A0A590UKC5_HUMAN,tr|M0QX65|M0QX65_HUMAN,tr|A0A590UKA0|A0A590UKA0_HUMAN,tr|A0A590UK93|A0A590UK93_HUMAN" 7 826.5276 2.97 56571 13408 2 826.526763 414.2711 SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1 PE=1 SV=1 8.75 2945 - 1.43E+06 - - - -1.0599 - 1.382 0.062 - 113.5 3 2 0 -0.0009 8 0 0 0 6.76E+07 2.27E+07 - - - 0.2613 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.13410.13410.2 4.68 18-Dec R.LLAEPVPGIK[136.11].A "sp|P61088|UBE2N_HUMAN,sp|Q5JXB2|UE2NL_HUMAN,tr|F8VZ29|F8VZ29_HUMAN,tr|F8VSD4|F8VSD4_HUMAN,tr|F8VV71|F8VV71_HUMAN" 5 1043.647 1.58 56572 13410 2 1043.646077 522.8308 Ubiquitin-conjugating enzyme E2 N OS=Homo sapiens OX=9606 GN=UBE2N PE=1 SV=1 6 2945.3 - 940063 - - - -0.9151 - 1.904 0.273 - 345.1 1 2 0 -0.001 10 0 0 0 1.57E+08 9.94E+07 - - - 2.8546 0.9965 230117_WJC_METTL3_WT_vs_EV_F07.13415.13415.2 0.682 14-Jul K.LVALNLDR.L "sp|Q9Y3D3|RT16_HUMAN,tr|A6ND22|A6ND22_HUMAN" 2 912.5393 1.18 56574 13415 2 912.538978 457.2769 "28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1" 5.84 2946 - 639986 - - - -0.3156 - 1.497 0.2 - 108.9 1 2 0 -0.0003 8 0 0 0 9.87E+07 8.33E+07 - - - 1.7349 1 230117_WJC_METTL3_WT_vs_EV_F07.13416.13416.2 9.32E-09 24-Dec R.TTPSYVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1486.694 17.04 56575 13416 2 1486.694169 744.3543 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2946.1 - 790386 - - - 0.1211 - 2.547 0.655 - 498 1 2 0 0.0002 13 0 0 0 1.03E+08 6.02E+06 - - - 6.2783 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.13420.13420.2 0.0252 12-Jul K.YVIYIER[166.11].V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 964.5257 0.79 56576 13420 2 964.527127 483.2701 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 6 2946.6 - 486164 - - - 1.4401 - 1.513 0.379 - 210.6 1 2 0 0.0014 7 0 0 0 1.05E+09 1.33E+09 - - - 3.1519 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.13424.13424.2 0.165 16-Sep K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 219.73 56579 13424 2 1059.556792 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2947.1 - 770340 - - - 0.7116 - 1.624 0.318 - 270.6 1 2 0 0.0008 9 0 0 0 3.16E+07 1.44E+05 - - - 2.7923 0.9937 230117_WJC_METTL3_WT_vs_EV_F07.13427.13427.2 1.02 14-Jul K.LVALNLDR[166.11].L "sp|Q9Y3D3|RT16_HUMAN,tr|A6ND22|A6ND22_HUMAN" 2 922.5475 1.21 56580 13427 2 922.547731 462.281 "28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1" 5.84 2947.5 - 2.74E+06 - - - 0.2114 - 1.233 0.199 - 100.9 2 2 0 0.0002 8 0 0 0 1.01E+08 8.35E+07 - - - 1.008 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.13429.13429.2 0.449 12-Jul K.IVVLLQR.L "sp|Q06323|PSME1_HUMAN,tr|H0YLU2|H0YLU2_HUMAN" 2 839.5593 1.38 56582 13429 2 839.558748 420.7869 Proteasome activator complex subunit 1 OS=Homo sapiens OX=9606 GN=PSME1 PE=1 SV=1 9.75 2947.6 - 1.34E+06 - - - -0.6253 - 1.605 0.272 - 147.2 1 2 0 -0.0005 7 0 0 0 3.75E+07 2.72E+07 - - - 2.5489 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.13434.13434.2 0.0045 18-Aug R.AFGSLGPGLR.L "sp|Q96JG8|MAGD4_HUMAN,tr|D6RBW3|D6RBW3_HUMAN,tr|A0A804HHZ9|A0A804HHZ9_HUMAN" 3 973.5345 9.19 56585 13434 2 973.535824 487.7745 Melanoma-associated antigen D4 OS=Homo sapiens OX=9606 GN=MAGED4 PE=1 SV=3 9.79 2948.3 - 677168 - - - 1.3446 - 1.514 0.371 - 165.3 1 2 0 0.0013 10 0 0 0 2.80E+07 3.05E+06 - - - 2.9385 0.997 230117_WJC_METTL3_WT_vs_EV_F07.13437.13437.2 0.0149 12-Aug K.YVIYIER.V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 954.5175 0.79 56586 13437 2 954.516391 478.266 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 6 2948.7 - 1.96E+06 - - - -1.1283 - 1.415 0.301 - 268.3 1 2 0 -0.0011 7 0 0 0 1.05E+09 1.33E+09 - - - 2.3637 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.13438.13438.2 0.136 14-Sep R.ILEVLPGR.R sp|Q9UI43|MRM2_HUMAN 1 895.5491 3.1 56587 13438 2 895.551135 448.7818 "rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1" 6 2948.8 - 813763 - - - 2.2701 - 1.698 0.258 - 234.7 1 2 0 0.002 8 0 0 0 8.60E+07 2.77E+07 - - - 2.5428 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.13442.13442.2 0.0134 12-May R.VVFQEFR[166.11].Q sp|P35579|MYH9_HUMAN 1 933.4948 0.89 56589 13442 2 933.495443 467.7547 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2949.3 - 1.36E+06 - - - 0.7188 - 1.214 0.334 - 119.9 1 2 0 0.0007 7 0 0 0 2.94E+08 3.29E+08 - - - 2.1222 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.13443.13443.2 0.0128 24-Sep R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 17.02 56590 13443 2 1496.701316 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2949.4 - 281393 - - - -0.6301 - 2.177 0.383 - 259.9 1 2 0 -0.0009 13 0 0 0 1.02E+08 6.02E+06 - - - 3.8662 0.9942 230117_WJC_METTL3_WT_vs_EV_F07.13444.13444.2 0.922 12-Jun K.ELVVLPR.E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 824.512 0.43 56591 13444 2 824.512828 413.2633 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2949.5 - 1.12E+06 - - - 1.0176 - 1.316 0.132 - 184.7 1 2 0 0.0008 7 0 0 0 1.93E+08 4.50E+08 - - - 0.8858 0.9951 230117_WJC_METTL3_WT_vs_EV_F07.13465.13465.2 0.0397 14-Jun R.LLSTYLER[166.11].Y "sp|Q12769|NU160_HUMAN,tr|G3V198|G3V198_HUMAN" 2 1003.5578 1.37 56600 13465 2 1003.561214 502.7862 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 6 2952.2 - 1.08E+06 - - - 3.4358 - 1.362 0.235 - 100 1 2 0 0.0034 8 0 0 0 6.64E+07 4.85E+07 - - - 1.7074 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.13474.13474.2 0.359 14-Oct R.LGALALPR.G "sp|Q6SPF0|SAMD1_HUMAN,tr|E9PIW9|E9PIW9_HUMAN" 2 809.5123 2.13 56604 13474 2 809.512955 405.7634 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.75 2953.5 - 3.14E+06 - - - 0.7807 - 2.039 0.159 - 309.4 1 2 0 0.0006 8 0 0 0 2.26E+08 1.06E+08 - - - 2.3639 0.996 230117_WJC_METTL3_WT_vs_EV_F07.13487.13487.2 0.0553 12-Jun K.ELVVLPR[166.11].E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 834.5203 0.49 56608 13487 2 834.522234 418.2674 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2955.3 - 8.10E+06 - - - 2.3666 - 1.268 0.211 - 149.1 1 2 0 0.002 7 0 0 0 2.24E+08 4.53E+08 - - - 1.3512 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.13488.13488.2 0.869 14-Aug R.LGALALPR[166.11].G "sp|Q6SPF0|SAMD1_HUMAN,tr|E9PIW9|E9PIW9_HUMAN" 2 819.5206 2.13 56609 13488 2 819.521817 410.7676 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.75 2955.4 - 1.69E+06 - - - 1.4936 - 1.93 0.22 - 252.9 1 2 0 0.0012 8 0 0 0 2.25E+08 1.06E+08 - - - 2.6486 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.13489.13489.2 0.541 12-Jun R.YLLAMER.H "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 894.4633 2.56 56610 13489 2 894.464685 448.2389 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 2955.5 - 903405 - - - 1.5216 - 1.401 0.251 - 120.2 1 2 0 0.0014 7 0 0 0 4.64E+07 1.81E+07 - - - 1.9629 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.13496.13496.2 0.128 16-Sep R.ILVGTNLVR.L sp|Q96QK1|VPS35_HUMAN 1 983.6128 1.9 56614 13496 2 983.614281 492.8137 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 9.75 2956.3 - 2.36E+06 - - - 1.5413 - 1.609 0.197 - 197.3 1 2 0 0.0015 9 0 0 0 7.96E+07 4.19E+07 - - - 1.8715 0.9641 230117_WJC_METTL3_WT_vs_EV_F07.13501.13501.2 0.00119 26-Jul L.GDVTITNDGATILK.L "sp|P17987|TCPA_HUMAN,sp|P50991|TCPD_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 7 1416.746 0.41 56616 13501 2 1416.74823 709.3803 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 2957 - 133155 - - - 1.5571 - 1.682 0.404 - 70 1 1 0 0.0022 14 0 0 0 1.89E+06 4.62E+06 - - - 3.3291 0.9957 230117_WJC_METTL3_WT_vs_EV_F07.13506.13506.2 1.13 12-Jun R.EALGLLR.A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 770.465 1.11 56619 13506 2 770.466934 386.2398 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2957.6 - 2.18E+06 - - - 2.4609 - 1.336 0.185 - 158.3 1 2 0 0.0019 7 0 0 0 2.33E+08 2.09E+08 - - - 1.3247 0.9944 230117_WJC_METTL3_WT_vs_EV_F07.13507.13507.2 0.478 14-Jul K.LLIIGPQK.T "sp|P52848|NDST1_HUMAN,tr|E7EVJ3|E7EVJ3_HUMAN" 2 880.5746 0.81 56620 13507 2 880.578633 441.2946 Bifunctional heparan sulfate N-deacetylase\N-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=NDST1 PE=1 SV=1 8.75 2957.7 - 519833 - - - 4.5925 - 1.471 0.286 - 151.9 1 2 0 0.004 8 0 0 0 2.06E+07 2.54E+07 - - - 2.3161 0.997 230117_WJC_METTL3_WT_vs_EV_F07.13511.13511.2 0.353 12-Jul R.EALGLLR[166.11].A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 780.4733 1.11 56622 13511 2 780.475019 391.2439 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2958.1 - 3.55E+06 - - - 2.1923 - 1.498 0.164 - 187 1 2 0 0.0017 7 0 0 0 2.33E+08 2.09E+08 - - - 1.5323 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.13512.13512.2 0.000775 14-Aug K.MMMVLGAK.W "sp|Q14839|CHD4_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|F5H6N4|F5H6N4_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 17 879.438 1.31 56623 13512 2 879.44001 440.7263 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.5 2958.3 - 677692 - - - 2.2435 - 1.513 0.336 - 168.5 1 2 0 0.002 8 0 0 0 2.28E+07 1.75E+07 - - - 2.771 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.13515.13515.2 0.00569 24-Sep K.VIDPATATSVDLR.D sp|P50991|TCPD_HUMAN 1 1356.7249 999 56626 13515 2 1356.725663 679.3697 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 2958.6 - 145758 - - - 0.5661 - 1.739 0.349 - 210.3 1 2 0 0.0008 13 0 0 0 9.66E+06 0.00E+00 - - - 3.0386 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.13519.13519.2 0.0215 12-Jul R.VVFQEFR.Q sp|P35579|MYH9_HUMAN 1 923.4865 0.89 56628 13519 2 923.488395 462.7505 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2959.1 - 4.79E+06 - - - 2.0498 - 1.452 0.367 - 223.1 1 2 0 0.0019 7 0 0 0 2.97E+08 3.32E+08 - - - 2.9328 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.13520.13520.2 0.0214 16-Sep R.MPVGSPLLR[166.11].D "sp|Q9NVS2|RT18A_HUMAN,tr|Q5QPA5|Q5QPA5_HUMAN" 2 978.556 1.27 56629 13520 2 978.558758 490.2853 "39S ribosomal protein S18a, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18A PE=1 SV=1" 9.5 2959.2 - 459980 - - - 2.8266 - 1.498 0.298 - 187.8 1 2 0 0.0028 9 0 0 0 1.08E+08 8.49E+07 - - - 2.4103 0.9634 230117_WJC_METTL3_WT_vs_EV_F07.13525.13525.2 0.0121 12-Aug K.PSVYFIK[136.11].F "sp|Q99865|SPI2A_HUMAN,sp|Q56A73|SPIN4_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 9 860.4887 0.49 56632 13525 2 860.490621 431.2516 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 9.01 2959.9 - 5.09E+06 - - - 2.1848 - 1.831 0.352 - 198 1 1 0 0.0019 7 0 0 0 2.87E+08 5.83E+08 - - - 3.5568 0.9956 230117_WJC_METTL3_WT_vs_EV_F07.13530.13530.2 0.487 12-Jun K.VLLDQLR[166.11].F "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 865.5261 1.65 56635 13530 2 865.528151 433.7703 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 5.81 2960.4 - 3.33E+06 - - - 2.402 - 1.312 0.187 - 71.7 1 2 0 0.0021 7 0 0 0 2.93E+08 1.78E+08 - - - 1.282 0.9851 230117_WJC_METTL3_WT_vs_EV_F07.13535.13535.2 1.13 12-Jun K.QLLYLEK.Y "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 3 905.5222 1 56638 13535 2 905.524234 453.7684 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 6 2960.9 - 1.71E+06 - - - 2.2252 - 1.061 0.149 - 109.5 1 2 0 0.002 7 0 0 0 7.12E+07 7.09E+07 - - - 0.3285 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.13537.13537.2 0.00305 20-Aug K.QAGVFEPTIVK.V "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1187.655 45.97 56640 13537 2 1187.658692 594.8348 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2961.2 - 119295 - - - 3.0884 - 1.548 0.323 - 130.4 1 2 0 0.0037 11 0 0 0 2.12E+07 4.61E+05 - - - 2.6076 0.972 230117_WJC_METTL3_WT_vs_EV_F07.13542.13542.2 0.0321 16-Jul K.LLNYAPLEK.- sp|P62875|RPAB5_HUMAN 1 1059.5964 1.2 56643 13542 2 1059.604353 530.8055 "DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1" 6 2961.8 - 669337 - - - 7.4613 - 1.486 0.32 - 130.5 1 2 0 0.0079 9 0 0 0 2.11E+07 1.76E+07 - - - 2.5479 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.13543.13543.2 0.000204 20-Jul K.NFYYAAVPSAR.N sp|Q10471|GALT2_HUMAN 1 1257.6142 0.88 56644 13543 2 1257.615419 629.8144 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.59 2961.9 - 91161 - - - 0.9518 - 1.48 0.393 - 91.7 1 2 0 0.0012 11 0 0 0 1.38E+06 1.57E+06 - - - 3.0039 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.13561.13561.2 0.0256 12-Jul R.VVFQEFR.Q sp|P35579|MYH9_HUMAN 1 923.4865 0.89 56655 13561 2 923.489291 462.7505 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2964.1 - 605419 - - - 3.0201 - 1.364 0.263 - 136.4 1 2 0 0.0028 7 0 0 0 2.97E+08 3.32E+08 - - - 1.9662 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.13566.13566.2 0.194 16-Sep R.IVDPEIALK.L "sp|P33240|CSTF2_HUMAN,tr|A0A0A0MT56|A0A0A0MT56_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 996.5855 1.75 56657 13566 2 996.58757 499.3001 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.37 2964.8 - 1.95E+06 - - - 2.0289 - 1.822 0.294 - 197.2 1 2 0 0.002 9 0 0 0 6.32E+08 3.61E+08 - - - 2.9475 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.13568.13568.2 0.0242 20-Jul K.NFYYAAVPSAR[166.11].N sp|Q10471|GALT2_HUMAN 1 1267.6225 0.88 56658 13568 2 1267.624702 634.8185 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.59 2965 - 119929 - - - 1.7434 - 1.315 0.299 - 103.9 1 2 0 0.0022 11 0 0 0 1.38E+06 1.57E+06 - - - 1.9895 0.9851 230117_WJC_METTL3_WT_vs_EV_F07.13575.13575.2 4.93 14-Aug K.IADFGLAR[166.11].L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 871.4791 2.01 56661 13575 2 871.47979 436.7468 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2966 - 1.89E+06 - - - 0.7665 - 1.432 0.017 - 174.2 1 2 0 0.0007 8 0 0 0 1.17E+09 5.82E+08 - - - 0.2493 0.9918 230117_WJC_METTL3_WT_vs_EV_F07.13589.13589.2 0.201 12-Jul R.FILIQNR.A "sp|P53680|AP2S1_HUMAN,tr|M0R0N4|M0R0N4_HUMAN,tr|X6R390|X6R390_HUMAN,tr|M0QYZ2|M0QYZ2_HUMAN" 4 902.5338 1.08 56670 13589 2 902.532697 452.2742 AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2 9.75 2967.5 - 1.14E+06 - - - -1.2077 - 1.369 0.194 - 177.1 1 2 0 -0.0011 7 0 0 0 4.52E+07 4.16E+07 - - - 1.4687 0.9952 230117_WJC_METTL3_WT_vs_EV_F07.13601.13601.2 0.312 14-Oct K.IADFGLAR.L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 861.4709 2 56676 13601 2 861.468106 431.7427 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2969.1 - 1.48E+07 - - - -3.1876 - 2.008 0.305 - 269.1 1 2 0 -0.0027 8 0 0 0 1.16E+09 5.81E+08 - - - 3.3954 0.999 230117_WJC_METTL3_WT_vs_EV_F07.13607.13607.2 0.112 14-Sep K.LLQLVEDR.G "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 984.5604 0.61 56680 13607 2 984.561395 493.2875 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 2969.8 - 1.45E+06 - - - 1.0157 - 1.79 0.221 - 286.5 1 2 0 0.001 8 0 0 0 1.68E+08 2.77E+08 - - - 2.4289 0.9744 230117_WJC_METTL3_WT_vs_EV_F07.13611.13611.2 0.00106 16-Oct K.PLYVALAQR[166.11].K "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PIK9|A0A6I8PIK9_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 25 1039.6054 1.13 56682 13611 2 1039.605648 520.81 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.18 2970.3 - 934809 - - - 0.253 - 2.055 0.465 - 397.1 1 1 0 0.0003 9 0 0 0 4.55E+08 4.02E+08 - - - 4.5592 0.9897 230117_WJC_METTL3_WT_vs_EV_F07.13630.13630.2 0.00436 12-Aug R.YFEPLVK.K "sp|Q7L590|MCM10_HUMAN,tr|Q5T670|Q5T670_HUMAN" 2 894.4851 1.37 56692 13630 2 894.483715 448.2498 Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2 6 2972.8 - 888023 - - - -1.554 - 1.262 0.229 - 157.8 1 2 0 -0.0014 7 0 0 0 4.77E+07 3.49E+07 - - - 1.4693 0.9792 230117_WJC_METTL3_WT_vs_EV_F07.13640.13640.2 0.531 14-Jul K.LLQPLVPR[166.11].Y sp|Q8N8A6|DDX51_HUMAN 1 944.6047 1.1 56694 13640 2 944.60464 473.3096 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2974.2 - 528250 - - - -0.018 - 1.237 0.075 - 108.5 1 2 0 0 8 0 0 0 1.49E+08 1.35E+08 - - - 0.2364 0.9911 230117_WJC_METTL3_WT_vs_EV_F07.13643.13643.2 4.21 14-Oct R.LAVEALVR[166.11].T "sp|Q92839|HYAS1_HUMAN,tr|M0QXH4|M0QXH4_HUMAN,tr|G3V1S7|G3V1S7_HUMAN,tr|M0R2V0|M0R2V0_HUMAN" 4 879.5417 7.74 56695 13643 2 879.542103 440.7781 Hyaluronan synthase 1 OS=Homo sapiens OX=9606 GN=HAS1 PE=1 SV=2 6 2974.6 - 1.80E+06 - - - 0.4332 - 1.67 0.013 - 382.3 1 2 0 0.0004 8 0 0 0 6.97E+09 9.00E+08 - - - 0.6836 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.13648.13648.2 0.83 14-Jul K.LAVEAVLR.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 869.5335 7.75 56696 13648 2 869.533061 435.774 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 2975.4 - 1.66E+07 - - - -0.4497 - 1.635 0.241 - 182.2 1 2 0 -0.0004 8 0 0 0 6.97E+09 9.00E+08 - - - 2.3037 0.9941 230117_WJC_METTL3_WT_vs_EV_F07.13658.13658.2 0.00645 12-Jul K.C[160.03]FLTAMR.E "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN" 3 897.4201 1.79 56701 13658 2 897.419516 449.7173 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 8.25 2976.6 - 1.25E+06 - - - -0.6274 - 1.079 0.293 - 190.7 1 2 0 -0.0006 7 0 0 0 6.35E+07 3.54E+07 - - - 1.4458 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.13662.13662.2 0.023 14-Aug R.LLAFAEAR.A "sp|Q8WUY8|NAT14_HUMAN,sp|Q99519|NEUR1_HUMAN,tr|M0R1E3|M0R1E3_HUMAN,tr|E9PIF4|E9PIF4_HUMAN" 4 889.5022 1.92 56703 13662 2 889.501143 445.7584 Probable N-acetyltransferase 14 OS=Homo sapiens OX=9606 GN=NAT14 PE=1 SV=1 6 2977 - 2.12E+06 - - - -1.1343 - 1.8 0.375 - 155.3 1 2 0 -0.001 8 0 0 0 7.16E+07 3.73E+07 - - - 3.5832 0.9291 230117_WJC_METTL3_WT_vs_EV_F07.13663.13663.2 0.965 14-Aug R.ALVIVMGK[136.11].E "tr|G5E9Q6|G5E9Q6_HUMAN,tr|C9J0J7|C9J0J7_HUMAN" 2 837.5237 2.86 56704 13663 2 837.519852 419.7691 Profilin OS=Homo sapiens OX=9606 GN=PFN2 PE=1 SV=1 8.8 2977.1 - 1.16E+06 - - - -4.6494 - 1.544 0.146 - 181.6 1 2 0 -0.0039 8 0 0 0 1.12E+08 3.89E+07 - - - 1.4282 0.9933 230117_WJC_METTL3_WT_vs_EV_F07.13670.13670.2 0.0142 14-Aug K.LLQPLVPR.Y sp|Q8N8A6|DDX51_HUMAN 1 934.5964 1.1 56708 13670 2 934.594712 468.3055 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2977.9 - 2.04E+06 - - - -1.7922 - 1.327 0.284 - 201.6 1 2 0 -0.0017 8 0 0 0 1.49E+08 1.35E+08 - - - 1.9914 0.9969 230117_WJC_METTL3_WT_vs_EV_F07.13677.13677.2 0.0335 14-Aug R.ALVIVMGK.E "tr|G5E9Q6|G5E9Q6_HUMAN,tr|C9J0J7|C9J0J7_HUMAN" 2 829.5095 3.34 56712 13677 2 829.508452 415.762 Profilin OS=Homo sapiens OX=9606 GN=PFN2 PE=1 SV=1 8.8 2978.7 - 2.36E+06 - - - -1.3189 - 1.62 0.268 - 188.2 1 2 0 -0.0011 8 0 0 0 1.38E+08 4.14E+07 - - - 2.4751 0.982 230117_WJC_METTL3_WT_vs_EV_F07.13678.13678.2 0.654 12-Jul R.YLDELMK[136.11].L "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 918.4612 1.57 56713 13678 2 918.459962 460.2379 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 2978.8 - 717805 - - - -1.3534 - 1.288 0.146 - 137.6 1 2 0 -0.0012 7 0 0 0 6.36E+07 4.05E+07 - - - 0.9209 0.931 230117_WJC_METTL3_WT_vs_EV_F07.13687.13687.2 2.35 12-Jun R.YLDELMK.L "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 910.447 1.51 56716 13687 2 910.446384 456.2308 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 2980 - 1.70E+06 - - - -0.6821 - 0.978 0.097 - 98.4 1 2 0 -0.0006 7 0 0 0 6.57E+07 4.36E+07 - - - -0.3132 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.13688.13688.2 0.0211 14-Jul K.ILDVMYSR[166.11].L sp|P78527|PRKDC_HUMAN 1 1005.5193 0.96 56717 13688 2 1005.518234 503.7669 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 2980.2 - 723481 - - - -1.0323 - 1.529 0.274 - 116.1 1 2 0 -0.001 8 0 0 0 9.30E+07 9.66E+07 - - - 2.3451 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.13730.13730.2 0.0859 12-Aug R.YLLLNPK.E "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 859.5167 0.02 56730 13730 2 859.517477 430.7656 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 8.59 2985.9 - 1.14E+06 - - - 0.8575 - 1.609 0.152 - 247.2 1 2 0 0.0007 7 0 0 0 1.24E+08 6.32E+09 - - - 1.6704 0.9923 230117_WJC_METTL3_WT_vs_EV_F07.13731.13731.2 0.393 18-Aug K.QQLLIGAYAK.A sp|Q99832|TCPH_HUMAN 1 1103.6339 47.66 56731 13731 2 1103.633621 552.8242 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.59 2986.1 - 348557 - - - -0.2483 - 1.279 0.178 - 134.8 1 2 0 -0.0003 10 0 0 0 1.05E+07 2.21E+05 - - - 1.0425 0.9872 230117_WJC_METTL3_WT_vs_EV_F07.13732.13732.2 4.78 12-May K.EAVLLLK[136.11].K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 792.52 0.75 56732 13732 2 792.520217 397.2673 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 2986.1 - 2.12E+06 - - - 0.2221 - 1.189 0.151 - 95.4 3 2 0 0.0002 7 0 0 0 7.48E+08 1.00E+09 - - - 0.4916 0.9922 230117_WJC_METTL3_WT_vs_EV_F07.13741.13741.2 1.06 12-Jun K.EAVLLLK.K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 784.5058 0.74 56737 13741 2 784.505999 393.2602 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 2987.2 - 2.56E+06 - - - 0.2014 - 1.415 0.097 - 158.6 1 2 0 0.0002 7 0 0 0 7.47E+08 1.00E+09 - - - 0.8573 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.13747.13747.2 1.37 12-Aug R.LLQIIER[166.11].Y sp|P78527|PRKDC_HUMAN 1 893.5574 1.2 56741 13747 2 893.558033 447.786 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2988 - 3.60E+06 - - - 0.7397 - 1.598 0.104 - 229.5 1 2 0 0.0007 7 0 0 0 2.92E+08 2.44E+08 - - - 1.2942 0.9957 230117_WJC_METTL3_WT_vs_EV_F07.13748.13748.2 0.474 12-Jun K.VLEILGK[136.11].K "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 10 778.5044 2.41 56742 13748 2 778.505188 390.2595 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.97 2988.1 - 784619 - - - 1.0238 - 1.431 0.167 - 66.8 5 2 0 0.0008 7 0 0 0 6.06E+07 2.51E+07 - - - 1.0975 0.9822 230117_WJC_METTL3_WT_vs_EV_F07.13753.13753.2 0.0905 14-Jul R.DLAPIGIR.V "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 853.5022 0.9 56745 13753 2 853.504617 427.7584 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 5.84 2988.8 - 1.57E+06 - - - 2.8881 - 1.38 0.058 - 185.3 1 2 0 0.0025 8 0 0 0 2.66E+08 2.94E+08 - - - 0.44 0.8835 230117_WJC_METTL3_WT_vs_EV_F07.13759.13759.2 1.37 14-May R.LPANLLYK.Y sp|Q9NVR2|INT10_HUMAN 1 930.5539 1.4 56749 13759 2 930.555413 466.2842 Integrator complex subunit 10 OS=Homo sapiens OX=9606 GN=INTS10 PE=1 SV=2 8.59 2989.4 - 158537 - - - 1.6753 - 0.97 0.03 - 38.3 5 2 0 0.0016 8 0 0 0 1.04E+07 7.47E+06 - - - -1.142 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.13774.13774.2 0.237 14-Aug R.NLLSVAYK.N "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB2|A2IDB2_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|K7EIT4|K7EIT4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 22 906.5175 1.53 56757 13774 2 906.519565 454.266 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 8.59 2991.3 - 1.35E+07 - - - 2.3132 - 1.686 0.294 - 256.9 1 2 0 0.0021 8 0 0 0 5.55E+08 3.64E+08 - - - 2.7872 0.9674 230117_WJC_METTL3_WT_vs_EV_F07.13784.13784.2 0.0056 18-Oct T.LGSATALMIR[166.11].E "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 1041.588 0.98 56763 13784 2 1041.590625 521.8013 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 2992.4 - 593911 - - - 2.5 - 2.328 0.361 - 265.2 1 1 0 0.0026 10 0 0 0 1.97E+07 2.01E+07 - - - 4.0652 0.9909 230117_WJC_METTL3_WT_vs_EV_F07.13798.13798.2 0.0454 14-Jul K.AAFAPFGR[166.11].L "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 5 845.4423 1.46 56772 13798 2 845.44656 423.7284 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 9.79 2994 - 508620 - - - 4.9879 - 1.439 0.266 - 127.9 1 2 0 0.0042 8 0 0 0 3.02E+07 2.07E+07 - - - 2.102 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.13808.13808.2 1.79 14-Sep K.LALDYGIK[136.11].F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 899.5208 2.98 56779 13808 2 899.520815 450.7677 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 2995 - 1.20E+06 - - - 0.0511 - 1.915 0.203 - 211.3 1 2 0 0 8 0 0 0 5.54E+08 1.86E+08 - - - 2.4999 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.13816.13816.2 0.0027 18-Sep K.TEVNSGFFYK.T "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN,tr|J3KRI6|J3KRI6_HUMAN" 3 1190.5608 10.52 56785 13816 2 1190.56203 596.2877 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.66 2995.9 - 278705 - - - 1.0424 - 1.652 0.372 - 145.9 1 2 0 0.0012 10 0 0 0 5.95E+06 5.66E+05 - - - 3.1894 0.8582 230117_WJC_METTL3_WT_vs_EV_F07.13819.13819.2 1.28 12-Jul R.FESILPR[166.11].P sp|Q08211|DHX9_HUMAN 1 870.4839 0.94 56787 13819 2 870.484631 436.2492 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 2996.3 - 4.42E+06 - - - 0.8708 - 1.647 0.15 - 169.9 1 1 0 0.0008 7 0 0 0 1.60E+08 1.70E+08 - - - 1.7296 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.13823.13823.2 0.0198 14-Jul K.AAFAPFGR.L "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 5 835.4341 1.49 56790 13823 2 835.435357 418.7243 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 9.79 2996.7 - 1.02E+06 - - - 1.5369 - 1.439 0.218 - 164.9 1 2 0 0.0013 8 0 0 0 2.84E+07 1.91E+07 - - - 1.7484 0.9906 230117_WJC_METTL3_WT_vs_EV_F07.13836.13836.2 1.02 18-Aug R.AVLGPVPLTR.T sp|Q96S90|LYSM1_HUMAN 1 1021.6284 4.94 56799 13836 2 1021.631117 511.8215 LysM and putative peptidoglycan-binding domain-containing protein 1 OS=Homo sapiens OX=9606 GN=LYSMD1 PE=1 SV=1 9.79 2998 - 282711 - - - 2.6448 - 1.545 0.092 - 137.8 2 2 0 0.0027 10 0 0 0 5.22E+06 1.06E+06 - - - 0.7995 0.8865 230117_WJC_METTL3_WT_vs_EV_F07.13838.13838.2 0.945 14-Jul F.GPVLNYLR[166.11].H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 940.537 0.8 56800 13838 2 940.537739 471.2758 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 2998.2 - 739029 - - - 0.8166 - 1.718 0.176 - 207.2 1 1 0 0.0008 8 0 0 0 4.69E+07 5.88E+07 - - - 1.9728 0.999 230117_WJC_METTL3_WT_vs_EV_F07.13842.13842.2 0.0141 14-Aug R.FLGC[160.03]VDIK.D "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 950.4895 1.81 56803 13842 2 950.491857 476.252 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 5.83 2998.6 - 1.29E+06 - - - 2.4387 - 1.433 0.345 - 174.5 1 2 0 0.0023 8 0 0 0 4.53E+07 2.51E+07 - - - 2.6735 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.13843.13843.2 0.000406 22-Nov R.TVIIEQSWGSPK[136.11].V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1351.7227 2.49 56804 13843 2 1351.725227 676.8686 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 2998.8 - 172136 - - - 1.8576 - 2.12 0.423 - 382.2 1 2 0 0.0025 12 0 0 0 1.54E+07 6.20E+06 - - - 4.1416 0.9952 230117_WJC_METTL3_WT_vs_EV_F07.13852.13852.2 0.12 18-Aug R.VPGATMLLAK.L sp|Q02252|MMSA_HUMAN 1 999.5787 1.43 56809 13852 2 999.581226 500.7966 "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Homo sapiens OX=9606 GN=ALDH6A1 PE=1 SV=2" 8.72 2999.8 - 437659 - - - 2.5391 - 1.291 0.205 - 115.9 1 2 0 0.0025 10 0 0 0 1.51E+07 1.05E+07 - - - 1.2673 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.13863.13863.2 0.0677 12-May K.MSILGVR.S "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|E9PM98|E9PM98_HUMAN,tr|A0A494BZW0|A0A494BZW0_HUMAN" 8 774.4422 1.8 56815 13863 2 774.442813 388.2284 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 9.5 3001.3 - 1.27E+06 - - - 0.798 - 1.31 0.28 - 97.8 1 2 0 0.0006 7 0 0 0 4.81E+07 2.67E+07 - - - 1.9645 0.9916 230117_WJC_METTL3_WT_vs_EV_F07.13870.13870.2 0.0439 12-Jul R.ISPLQFR[166.11].- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 869.4999 2.94 56818 13870 2 869.501224 435.7572 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 3002.2 - 3.20E+06 - - - 1.571 - 1.363 0.079 - 203.3 1 2 0 0.0014 7 0 0 0 4.51E+08 1.53E+08 - - - 0.6053 0.909 230117_WJC_METTL3_WT_vs_EV_F07.13876.13876.2 1.36 14-Jun K.DVSGIFIR.S sp|Q8NDH2|CC168_HUMAN 1 905.4971 1.73 56821 13876 2 905.494686 453.7558 Coiled-coil domain-containing protein 168 OS=Homo sapiens OX=9606 GN=CCDC168 PE=2 SV=2 5.84 3002.9 - 705953 - - - -2.6295 - 1.23 0.122 - 53.5 4 2 0 -0.0024 8 0 0 0 2.93E+07 1.70E+07 - - - 0.2967 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.13877.13877.2 0.0238 14-Jun K.VLVPQIPR.L sp|Q10469|MGAT2_HUMAN 1 920.5807 1.12 56822 13877 2 920.583598 461.2976 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 3003 - 522069 - - - 3.1078 - 1.267 0.364 - 95.9 1 2 0 0.0029 8 0 0 0 1.33E+08 1.19E+08 - - - 2.4423 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.13878.13878.2 0.963 12-Jun K.LVYILNR[166.11].D sp|Q15393|SF3B3_HUMAN 1 899.5468 1.42 56823 13878 2 899.547623 450.7807 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 3003.1 - 6.30E+06 - - - 0.906 - 1.415 0.153 - 114.4 1 2 0 0.0008 7 0 0 0 3.55E+08 2.50E+08 - - - 1.2707 0.8969 230117_WJC_METTL3_WT_vs_EV_F07.13879.13879.4 0.694 9/108 L.LLLLLTVTLLLAQVTPVMK.C sp|Q5J5C9|DB121_HUMAN 1 2078.3153 197.36 56824 13879 4 2078.318697 520.5861 Beta-defensin 121 OS=Homo sapiens OX=9606 GN=DEFB121 PE=1 SV=1 8.75 3003.2 - 645428 - - - 1.6552 - 1.477 0.226 - 37.4 1 1 0 0.0034 19 0 0 0 1.57E+07 7.96E+04 - - - 1.3241 0.8473 230117_WJC_METTL3_WT_vs_EV_F07.13880.13880.2 11.5 16-Aug K.YDGIILPGK.- "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 974.5437 1.27 56825 13880 2 974.547602 488.2791 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.83 3003.3 - 310270 - - - 4.0214 - 1.107 0.013 - 147.6 1 2 0 0.0039 9 0 0 0 3.98E+07 3.13E+07 - - - -0.5701 0.9905 230117_WJC_METTL3_WT_vs_EV_F07.13884.13884.2 0.0507 12-Jul R.ISPLQFR.- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 859.4916 2.92 56827 13884 2 859.493395 430.7531 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 3003.8 - 1.08E+07 - - - 2.1024 - 1.405 0.066 - 232.9 1 2 0 0.0018 7 0 0 0 4.30E+08 1.47E+08 - - - 0.6053 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.13885.13885.2 0.183 12-Jun K.LVYILNR.D sp|Q15393|SF3B3_HUMAN 1 889.5385 1.44 56828 13885 2 889.54034 445.7765 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 3003.9 - 8.98E+06 - - - 2.0258 - 1.299 0.285 - 140.1 1 2 0 0.0018 7 0 0 0 3.65E+08 2.53E+08 - - - 1.9743 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.13889.13889.2 0.0156 22-Oct R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 2.49 56832 13889 2 1343.711511 672.8615 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 3004.4 - 453944 - - - 2.2289 - 2.009 0.381 - 131.9 1 2 0 0.003 12 0 0 0 1.54E+07 6.20E+06 - - - 3.6897 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.13894.13894.2 0.0177 14-Jul K.ITAFIVER[166.11].D "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 957.5523 0.78 56835 13894 2 957.554455 479.7834 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 6 3005 - 1.02E+06 - - - 2.2641 - 1.665 0.289 - 139.7 1 2 0 0.0022 8 0 0 0 5.35E+07 6.88E+07 - - - 2.7125 0.993 230117_WJC_METTL3_WT_vs_EV_F07.13896.13896.2 0.0193 12-Jul R.YYFEGIK[136.11].Q "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN" 3 926.4629 2.49 56837 13896 2 926.460671 464.2387 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 6 3005.1 - 652950 - - - -2.4275 - 1.247 0.353 - 130.8 1 2 0 -0.0022 7 0 0 0 5.92E+07 2.38E+07 - - - 2.347 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.13897.13897.2 0.017 16-Sep K.VPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1071.5601 1.79 56838 13897 2 1071.563694 536.7873 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 3005.3 - 584047 - - - 3.3904 - 1.402 0.317 - 269.8 1 2 0 0.0036 9 0 0 0 2.03E+07 1.14E+07 - - - 2.3588 0.999 230117_WJC_METTL3_WT_vs_EV_F07.13899.13899.2 0.02 18-Oct K.ILAEESYLYK.H sp|Q9NVX0|HAUS2_HUMAN 1 1227.6387 2.73 56840 13899 2 1227.642368 614.8266 HAUS augmin-like complex subunit 2 OS=Homo sapiens OX=9606 GN=HAUS2 PE=1 SV=1 4.53 3005.5 - 235336 - - - 2.9838 - 1.76 0.341 - 246.2 1 2 0 0.0037 10 0 0 0 5.15E+06 1.89E+06 - - - 3.1364 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.13904.13904.2 0.0164 14-Sep K.ITAFIVER.D "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 947.544 0.48 56843 13904 2 947.545696 474.7793 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 6 3006.1 - 1.24E+06 - - - 1.7719 - 1.892 0.363 - 245.1 1 2 0 0.0017 8 0 0 0 5.76E+07 1.20E+08 - - - 3.6447 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.13909.13909.2 0.501 14-Jul K.VLVPQIPR[166.11].L sp|Q10469|MGAT2_HUMAN 1 930.589 1.12 56846 13909 2 930.590009 466.3018 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 3006.7 - 889478 - - - 1.0767 - 1.335 0.212 - 162 1 2 0 0.001 8 0 0 0 1.33E+08 1.19E+08 - - - 1.4779 0.9754 230117_WJC_METTL3_WT_vs_EV_F07.13912.13912.2 3.51 14-May R.VIFTSPIK[136.11].A sp|P42285|MTREX_HUMAN 1 911.5572 1.06 56849 13912 2 911.558663 456.7859 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 8.72 3007 - 704016 - - - 1.6554 - 1.093 0.138 - 68.2 10 2 0 0.0015 8 0 0 0 1.48E+08 1.39E+08 - - - -0.1187 0.9938 230117_WJC_METTL3_WT_vs_EV_F07.13915.13915.2 0.05 12-Jul K.FTAILYR.T "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 882.4963 0.59 56850 13915 2 882.499255 442.2554 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.75 3007.4 - 3.76E+06 - - - 3.3043 - 1.553 0.135 - 221.6 1 2 0 0.0029 7 0 0 0 1.48E+08 2.50E+08 - - - 1.432 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.13922.13922.2 0.0183 14-Aug K.VGVNGFGR.L sp|P04406|G3P_HUMAN 1 804.4242 2.6 56855 13922 2 804.425909 403.2194 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 3008.2 - 1.21E+06 - - - 2.0797 - 1.556 0.371 - 192.6 1 2 0 0.0017 8 0 0 0 5.55E+07 2.14E+07 - - - 3.1141 0.9913 230117_WJC_METTL3_WT_vs_EV_F07.13923.13923.2 0.327 12-Jul R.VLDFDVK.R "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 834.4487 0.72 56856 13923 2 834.451906 418.2316 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 4.21 3008.3 - 511652 - - - 3.8181 - 1.407 0.177 - 115.4 1 2 0 0.0032 7 0 0 0 4.43E+07 6.19E+07 - - - 1.4293 0.9931 230117_WJC_METTL3_WT_vs_EV_F07.13927.13927.2 10.4 12-Aug R.LVQLLVK.A sp|P14923|PLAK_HUMAN 1 811.5531 18.81 56858 13927 2 811.554357 406.7838 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 8.75 3008.7 - 3.21E+06 - - - 1.5181 - 1.443 0.073 - 171.1 1 2 0 0.0012 7 0 0 0 2.88E+08 1.53E+07 - - - 0.7418 0.9752 230117_WJC_METTL3_WT_vs_EV_F07.13930.13930.2 1.56 12-Jun R.YYFEGIK.Q "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN" 3 918.4487 2.42 56860 13930 2 918.450679 460.2316 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 6 3009.1 - 1.25E+06 - - - 2.1329 - 0.922 0.159 - 99.6 1 2 0 0.002 7 0 0 0 5.88E+07 2.43E+07 - - - -0.0426 0.999 230117_WJC_METTL3_WT_vs_EV_F07.13932.13932.2 0.0186 16-Aug R.VLLLEAGPK.D "sp|Q8NE62|CHDH_HUMAN,tr|C9J7D8|C9J7D8_HUMAN,tr|C9JYW4|C9JYW4_HUMAN" 3 938.5801 5.26 56861 13932 2 938.581665 470.2973 "Choline dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=CHDH PE=1 SV=2" 5.97 3009.3 - 572198 - - - 1.7015 - 1.602 0.267 - 156.4 1 2 0 0.0016 9 0 0 0 1.84E+07 3.49E+06 - - - 2.3759 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.13937.13937.2 0.0426 18-Sep R.YPVNSVNILK.A "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1145.6445 20.65 56864 13937 2 1145.646345 573.8295 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.59 3009.9 - 523805 - - - 1.6462 - 1.819 0.271 - 119 1 2 0 0.0019 10 0 0 0 2.23E+07 1.08E+06 - - - 2.712 0.9869 230117_WJC_METTL3_WT_vs_EV_F07.13942.13942.2 0.00866 16-Jul R.VPPEFLVQR.A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1083.6077 1.28 56867 13942 2 1083.610753 542.8111 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3010.6 - 271936 - - - 2.8359 - 1.345 0.1 - 140.5 1 2 0 0.0031 9 0 0 0 9.56E+07 7.49E+07 - - - 0.6361 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.13964.13964.2 0.0108 16-Aug R.VPPEFLVQR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1093.616 1.45 56882 13964 2 1093.616255 547.8153 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3013.2 - 227229 - - - 0.2789 - 1.432 0.306 - 192.5 1 2 0 0.0003 9 0 0 0 6.22E+07 4.30E+07 - - - 2.3398 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.13970.13970.2 0.194 14-Aug R.LPWAVAGR.S sp|Q8NBX0|SCPDL_HUMAN 1 868.4919 1.93 56886 13970 2 868.493175 435.2532 Saccharopine dehydrogenase-like oxidoreductase OS=Homo sapiens OX=9606 GN=SCCPDH PE=1 SV=1 9.75 3013.8 - 1.13E+06 - - - 1.4427 - 1.401 0.17 - 203.6 1 2 0 0.0013 8 0 0 0 8.44E+07 4.38E+07 - - - 1.3132 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.13980.13980.2 0.000508 12-Jun K.LFEMAYK.K "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 900.4415 4.44 56892 13980 2 900.442407 451.228 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6 3015 - 9.05E+06 - - - 0.9784 - 1.399 0.43 - 134 1 2 0 0.0009 7 0 0 0 1.83E+09 4.11E+08 - - - 3.2806 0.8628 230117_WJC_METTL3_WT_vs_EV_F07.13982.13982.2 4.29 16-Apr R.IIFSPVAPK[136.11].E sp|O15294|OGT1_HUMAN 1 978.5994 1.33 56894 13982 2 978.600391 490.307 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 8.75 3015.2 - 629038 - - - 1.0597 - 1.02 0.06 - 21 63 2 0 0.001 9 0 0 0 1.38E+08 1.04E+08 - - - -1.2626 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.13994.13994.2 0.021 18-Jul K.VLQSALAAIR.H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1040.6342 1.04 56900 13994 2 1040.635623 521.3244 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 3016.9 - 390741 - - - 1.3396 - 1.484 0.22 - 95 1 2 0 0.0014 10 0 0 0 3.33E+08 3.21E+08 - - - 1.7673 0.9164 230117_WJC_METTL3_WT_vs_EV_F07.13997.13997.2 0.818 16-Jul R.IIFSPVAPK.E sp|O15294|OGT1_HUMAN 1 970.5852 1.33 56903 13997 2 970.590466 486.2999 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 8.75 3017 - 1.12E+06 - - - 5.473 - 1.266 0.108 - 121.6 1 2 0 0.0053 9 0 0 0 1.37E+08 1.03E+08 - - - 0.5194 0.9909 230117_WJC_METTL3_WT_vs_EV_F07.14002.14002.2 0.19 18-Sep R.VLAESLGPLR.E sp|Q4KMQ1|TPRN_HUMAN 1 1053.6182 1.35 56905 14002 2 1053.61486 527.8164 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 5.97 3017.7 - 528546 - - - -3.2127 - 1.817 0.254 - 180.5 1 2 0 -0.0034 10 0 0 0 7.89E+07 5.83E+07 - - - 2.5829 0.9724 230117_WJC_METTL3_WT_vs_EV_F07.14003.14003.2 2.88 12-Jul R.NLVSYLK.Q "sp|Q96T37|RBM15_HUMAN,sp|Q8NDT2|RB15B_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 5 835.4804 0.64 56906 14003 2 835.48119 418.7475 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 8.59 3017.8 - 749346 - - - 1.0006 - 1.097 0.064 - 131.2 1 2 0 0.0008 7 0 0 0 3.92E+07 6.11E+07 - - - -0.1932 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.14009.14009.2 0.0136 18-Sep K.VLQSALAAIR[166.11].H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1050.6425 1.04 56908 14009 2 1050.64346 526.3285 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 3018.6 - 2.05E+06 - - - 0.9147 - 1.957 0.303 - 277.2 1 2 0 0.001 10 0 0 0 3.33E+08 3.21E+08 - - - 3.1528 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.14024.14024.2 0.139 14-Aug R.YPEEFALR.D "sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN" 4 1023.5025 0.51 56913 14024 2 1023.503189 512.7585 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.53 3020.7 - 490262 - - - 0.6282 - 1.188 0.373 - 180.3 1 2 0 0.0006 8 0 0 0 2.32E+07 4.55E+07 - - - 2.3153 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.14030.14030.2 0.00181 16-Aug R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 76902.57 56915 14030 2 1030.592269 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 3021.5 - 2.99E+07 - - - 1.2051 - 1.797 0.285 - 163.8 1 2 0 0.0012 9 0 0 0 5.80E+09 7.54E+04 - - - 2.8413 0.9664 230117_WJC_METTL3_WT_vs_EV_F07.14035.14035.2 1.43 12-Jun K.TISLVIR[166.11].G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 810.5203 1.64 56918 14035 2 810.521392 406.2674 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 9.41 3022.1 - 671719 - - - 1.3979 - 1.134 0.03 - 92.5 1 2 0 0.0011 7 0 0 0 7.01E+07 4.27E+07 - - - -0.3393 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.14037.14037.2 0.0413 12-Jul K.VWVQAFK.V sp|P11279|LAMP1_HUMAN 1 876.4858 5.54 56919 14037 2 876.487126 439.2502 Lysosome-associated membrane glycoprotein 1 OS=Homo sapiens OX=9606 GN=LAMP1 PE=1 SV=3 8.72 3022.3 - 891342 - - - 1.5425 - 1.47 0.251 - 216.4 1 2 0 0.0014 7 0 0 0 5.95E+07 1.08E+07 - - - 2.1152 0.9877 230117_WJC_METTL3_WT_vs_EV_F07.14044.14044.2 0.124 12-Jun R.FPPYYMR[166.11].R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 982.461 0.91 56922 14044 2 982.462197 492.2378 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 3023.2 - 342289 - - - 1.1889 - 0.923 0.209 - 85 1 2 0 0.0012 7 0 0 0 1.89E+07 2.08E+07 - - - 0.3304 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.14049.14049.2 0.00119 18-Oct R.VLAESLGPLR[166.11].E sp|Q4KMQ1|TPRN_HUMAN 1 1063.6265 1.35 56924 14049 2 1063.627196 532.8205 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 5.97 3023.9 - 1.21E+06 - - - 0.6403 - 1.908 0.288 - 338.1 1 2 0 0.0007 10 0 0 0 7.88E+07 5.83E+07 - - - 2.9713 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.14050.14050.2 0.12 18-Dec K.LAEALYIADR.K "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1133.6081 1.53 56925 14050 2 1133.608654 567.8113 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 3024 - 536898 - - - 0.5116 - 2.54 0.346 - 590.2 1 2 0 0.0006 10 0 0 0 6.38E+07 4.15E+07 - - - 4.1983 0.9524 230117_WJC_METTL3_WT_vs_EV_F07.14053.14053.2 0.299 12-Jun R.FLISYDR[166.11].T "sp|Q8TBX8|PI42C_HUMAN,tr|F8VNT5|F8VNT5_HUMAN,tr|F8VU68|F8VU68_HUMAN" 3 922.4788 0.98 56926 14053 2 922.47862 462.2467 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma OS=Homo sapiens OX=9606 GN=PIP4K2C PE=1 SV=3 5.84 3024.4 - 380670 - - - -0.1821 - 1.278 0.008 - 96.8 2 2 0 -0.0002 7 0 0 0 1.94E+07 1.98E+07 - - - -0.2572 0.9392 230117_WJC_METTL3_WT_vs_EV_F07.14064.14064.2 0.542 12-Jul K.SAEFLLH.M "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 815.4178 - 56934 14064 2 815.418838 408.7162 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 5.22 3025.7 - 1.40E+06 - - - 1.3294 - 1.495 0.31 - 223 1 1 0 0.0011 7 0 0 0 - - - - - 2.6045 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.14065.14065.2 0.000418 16-Aug K.FTPGAVMLR.V "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 990.5321 1.4 56935 14065 2 990.531269 496.2733 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.75 3025.9 - 567997 - - - -0.8107 - 1.535 0.385 - 186.5 1 2 0 -0.0008 9 0 0 0 6.16E+07 4.40E+07 - - - 3.1241 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.14069.14069.2 3.76 14-Aug R.VLVLVPTR[166.11].E "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 905.5938 0.88 56937 14069 2 905.593778 453.8042 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 9.72 3026.4 - 2.74E+06 - - - 0.0221 - 1.739 0.228 - 314.7 1 2 0 0 8 0 0 0 9.21E+07 1.05E+08 - - - 2.3938 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.14070.14070.2 3.68E-06 28-Dec K.NQVALNPQNTVFDAK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1657.8424 999 56938 14070 2 1657.84164 829.9285 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3026.5 - 186117 - - - -0.4488 - 2.049 0.504 - 249.6 1 2 0 -0.0007 15 0 0 0 7.02E+06 0.00E+00 - - - 4.527 0.967 230117_WJC_METTL3_WT_vs_EV_F07.14071.14071.2 0.00421 12-Jul R.LFVLTTK.N sp|Q96RS6|NUDC1_HUMAN 1 820.5058 2.21 56939 14071 2 820.509951 411.2602 NudC domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NUDCD1 PE=1 SV=2 8.75 3026.6 - 405600 - - - 5.0091 - 1.445 0.108 - 124.5 1 2 0 0.0041 7 0 0 0 4.19E+07 1.89E+07 - - - 1.0038 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.14084.14084.2 8.58E-05 20-Aug K.VMPTLAPVVAK.L sp|Q8IWI9|MGAP_HUMAN 1 1124.6628 1.19 56947 14084 2 1124.662079 563.3387 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 8.72 3028.1 - 228614 - - - -0.5984 - 1.736 0.476 - 140.1 1 2 0 -0.0007 11 0 0 0 7.26E+06 6.11E+06 - - - 4.0487 1 230117_WJC_METTL3_WT_vs_EV_F07.14093.14093.2 1.13E-05 18-Sep K.NLQEAEEWYK.S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1308.5986 1.79 56951 14093 2 1308.596875 655.3066 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3029.3 - 175669 - - - -1.3427 - 1.794 0.563 - 253.6 1 2 0 -0.0018 10 0 0 0 2.54E+07 1.42E+07 - - - 4.8301 0.8743 230117_WJC_METTL3_WT_vs_EV_F07.14097.14097.2 1.71 12-Jun R.FPPYYMR.R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 972.4528 1.29 56952 14097 2 972.455396 487.2337 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 3029.8 - 348458 - - - 2.7117 - 0.815 0.09 - 76.2 1 2 0 0.0026 7 0 0 0 6.34E+07 4.89E+07 - - - -0.9433 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.14098.14098.2 0.0662 18-Oct K.NLQEAEEWYK[136.11].S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1316.6128 1.79 56953 14098 2 1316.613835 659.3137 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3030 - 201448 - - - 0.7618 - 1.627 0.328 - 243.2 1 2 0 0.001 10 0 0 0 2.54E+07 1.42E+07 - - - 2.8219 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.14103.14103.2 0.0195 14-Aug R.EAVLSLYR.A sp|L0R8F8|MIDUO_HUMAN 1 949.5233 1 56956 14103 2 949.524626 475.7689 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 6.1 3030.5 - 1.22E+06 - - - 1.4154 - 1.696 0.296 - 220.6 1 2 0 0.0013 8 0 0 0 6.27E+07 6.27E+07 - - - 2.8201 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.14106.14106.2 4.40E-05 14-Aug R.VLVLVPTR.E "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 895.5855 0.88 56957 14106 2 895.586652 448.8 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 9.72 3030.9 - 2.18E+06 - - - 1.2997 - 1.726 0.386 - 260.1 1 2 0 0.0012 8 0 0 0 9.21E+07 1.05E+08 - - - 3.5378 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.14107.14107.2 0.0189 14-Aug R.VWAEYALK[136.11].R sp|Q6P2Q9|PRP8_HUMAN 1 986.5317 1.28 56958 14107 2 986.533786 494.2731 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3031 - 1.76E+06 - - - 2.1469 - 1.55 0.353 - 265.6 1 2 0 0.0021 8 0 0 0 3.00E+08 2.34E+08 - - - 2.9693 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.14112.14112.2 0.265 14-Aug R.LPLATIVK.D sp|O94776|MTA2_HUMAN 1 853.5637 1.5 56963 14112 2 853.565149 427.7891 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 3031.5 - 1.27E+06 - - - 1.7093 - 1.502 0.246 - 161.9 1 2 0 0.0015 8 0 0 0 3.51E+08 2.34E+08 - - - 2.0844 0.91 230117_WJC_METTL3_WT_vs_EV_F07.14127.14127.2 3.36 12-Jun R.GLIDSLR.A sp|P53992|SC24C_HUMAN 1 772.4443 0.17 56970 14127 2 772.442966 387.2294 Protein transport protein Sec24C OS=Homo sapiens OX=9606 GN=SEC24C PE=1 SV=3 5.84 3033.3 - 356370 - - - -1.7309 - 1.276 0.016 - 106.9 1 2 0 -0.0013 7 0 0 0 1.53E+07 9.26E+07 - - - -0.069 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.14129.14129.2 0.00354 14-Jul R.VWAEYALK.R sp|Q6P2Q9|PRP8_HUMAN 1 978.5175 1.14 56971 14129 2 978.517672 490.266 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3033.5 - 7.01E+06 - - - 0.2085 - 1.477 0.391 - 189.5 1 2 0 0.0002 8 0 0 0 3.08E+08 2.69E+08 - - - 3.1051 0.9969 230117_WJC_METTL3_WT_vs_EV_F07.14135.14135.2 0.137 14-Jul K.LYLADPMK.A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 949.4943 1.58 56975 14135 2 949.493531 475.7544 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 3034.1 - 2.55E+06 - - - -0.7994 - 1.34 0.299 - 148.7 1 2 0 -0.0008 8 0 0 0 3.82E+08 2.41E+08 - - - 2.1319 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.14140.14140.2 0.00316 14-Sep K.LYLADPMK[136.11].A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 957.5085 1.58 56977 14140 2 957.507208 479.7615 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 3034.8 - 2.09E+06 - - - -1.3389 - 1.736 0.412 - 253.9 1 2 0 -0.0013 8 0 0 0 3.82E+08 2.41E+08 - - - 3.7472 0.9931 230117_WJC_METTL3_WT_vs_EV_F07.14149.14149.2 9.26 14-Jun R.ALVLAQIR.K "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHA0|A0A6Q8PHA0_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF69|A0A6Q8PF69_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PGR0|A0A6Q8PGR0_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN,tr|A0A6Q8PFN8|A0A6Q8PFN8_HUMAN" 16 882.5651 1.81 56981 14149 2 882.566182 442.2898 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 9.79 3035.9 - 725431 - - - 1.2407 - 1.243 0.141 - 91.5 1 2 0 0.0011 8 0 0 0 2.15E+07 1.19E+07 - - - 0.7381 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.14154.14154.2 0.877 12-Sep K.IISIIVK.N "sp|Q9Y4A5|TRRAP_HUMAN,sp|Q6PEY0|CXB7_HUMAN,sp|Q96QE4|LR37B_HUMAN,tr|J3QSU1|J3QSU1_HUMAN,tr|J3KTP0|J3KTP0_HUMAN,tr|A0A0A0MRM5|A0A0A0MRM5_HUMAN,tr|J3QLI7|J3QLI7_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 9 784.5422 1.35 56984 14154 2 784.543319 393.2784 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3036.4 - 1.20E+06 - - - 1.3932 - 2.006 0.036 - 183.4 1 2 0 0.0011 7 0 0 0 2.51E+07 1.85E+07 - - - 1.5123 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.14157.14157.2 0.0219 16-Aug K.GVVTAEMFR.H "sp|Q8N3U4|STAG2_HUMAN,tr|B1AMT1|B1AMT1_HUMAN,tr|B1AMT4|B1AMT4_HUMAN,tr|B1AMT3|B1AMT3_HUMAN,tr|B1AMT2|B1AMT2_HUMAN" 5 1008.5063 2.42 56987 14157 2 1008.507822 505.2604 Cohesin subunit SA-2 OS=Homo sapiens OX=9606 GN=STAG2 PE=1 SV=3 6 3036.8 - 458107 - - - 1.5577 - 1.342 0.275 - 127.5 1 2 0 0.0016 9 0 0 0 1.24E+07 5.13E+06 - - - 1.9227 1 230117_WJC_METTL3_WT_vs_EV_F07.14161.14161.2 4.87E-05 18-Dec R.VPLVAPEDLR[166.11].D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1117.6371 0.5 56989 14161 2 1117.637829 559.8258 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3037.3 - 1.06E+06 - - - 0.6711 - 2.457 0.431 - 705.6 1 2 0 0.0008 10 0 0 0 1.18E+09 2.36E+09 - - - 4.7333 0.8499 230117_WJC_METTL3_WT_vs_EV_F07.14164.14164.2 3.17 14-Jun R.GGYDLLVR[166.11].S sp|Q9UBF2|COPG2_HUMAN 1 901.4897 0.94 56992 14164 2 901.492887 451.7521 Coatomer subunit gamma-2 OS=Homo sapiens OX=9606 GN=COPG2 PE=1 SV=1 5.84 3037.6 - 329723 - - - 3.5497 - 1.12 0 - 66.5 2 2 0 0.0032 8 0 0 0 1.91E+07 2.03E+07 - - - -0.7527 0.999 230117_WJC_METTL3_WT_vs_EV_F07.14167.14167.2 0.0131 12-Aug R.FTDILVR.H sp|O43143|DHX15_HUMAN 1 862.4913 1.08 56993 14167 2 862.490845 432.2529 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 3038 - 7.88E+06 - - - -0.473 - 1.595 0.361 - 226.2 1 2 0 -0.0004 7 0 0 0 8.32E+08 7.72E+08 - - - 3.1865 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.14178.14178.2 0.0161 12-Aug R.VFDMLNR[166.11].R "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 12 903.4512 1.58 57002 14178 2 903.451107 452.7329 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3039.3 - 716926 - - - -0.0952 - 1.566 0.282 - 218.5 1 2 0 -0.0001 7 0 0 0 9.84E+07 6.22E+07 - - - 2.545 1 230117_WJC_METTL3_WT_vs_EV_F07.14193.14193.2 0.000719 20-Dec K.YFVEAGAMAVR.R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1212.5961 10.16 57008 14193 2 1212.599352 607.3053 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3041.5 - 615735 - - - 2.6579 - 2.146 0.539 - 558.4 1 2 0 0.0032 11 0 0 0 9.14E+08 8.99E+07 - - - 5.0868 1 230117_WJC_METTL3_WT_vs_EV_F07.14194.14194.2 0.0371 18-Dec R.VPLVAPEDLR.D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1107.6288 0.5 57009 14194 2 1107.630044 554.8217 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3041.5 - 4.52E+06 - - - 1.115 - 2.473 0.414 - 831.7 1 2 0 0.0012 10 0 0 0 1.18E+09 2.36E+09 - - - 4.6258 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.14207.14207.2 0.00405 20-Oct K.YFVEAGAMAVR[166.11].R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1222.6044 10.13 57015 14207 2 1222.605999 612.3095 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3043.1 - 324795 - - - 1.3087 - 1.852 0.513 - 306.3 1 2 0 0.0016 11 0 0 0 9.07E+08 8.95E+07 - - - 4.4967 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.14208.14208.2 0.0496 26-Jun K.IFVGGLSPDTPEEK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1487.7508 1.43 57016 14208 2 1487.752198 744.8827 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3043.2 - 241748 - - - 0.9565 - 1.594 0.317 - 35.8 10 2 0 0.0014 14 0 0 0 1.45E+07 1.01E+07 - - - 2.1052 0.9947 230117_WJC_METTL3_WT_vs_EV_F07.14218.14218.2 0.276 12-Aug K.IAWALSR.K sp|Q04760|LGUL_HUMAN 1 815.4654 1.1 57020 14218 2 815.466315 408.74 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 9.75 3044.4 - 2.26E+06 - - - 1.1552 - 1.438 0.101 - 216.8 1 2 0 0.0009 7 0 0 0 1.73E+08 1.58E+08 - - - 0.9377 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.14223.14223.2 0.275 12-Aug R.SLEVILR[166.11].A sp|Q14566|MCM6_HUMAN 1 838.5152 1.04 57023 14223 2 838.516304 420.2649 DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1 5.72 3045 - 1.03E+06 - - - 1.3488 - 1.364 0.163 - 172.3 1 2 0 0.0011 7 0 0 0 7.09E+07 6.79E+07 - - - 1.2282 0.996 230117_WJC_METTL3_WT_vs_EV_F07.14227.14227.2 0.375 18-Aug R.VPYVIISAAK.G "sp|P28340|DPOD1_HUMAN,tr|M0QXQ2|M0QXQ2_HUMAN,tr|M0QXE6|M0QXE6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 5 1059.6328 1.78 57025 14227 2 1059.633647 530.8237 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 8.56 3045.5 - 353629 - - - 0.7691 - 1.509 0.137 - 154.2 1 2 0 0.0008 10 0 0 0 1.26E+07 7.10E+06 - - - 1.2011 0.9951 230117_WJC_METTL3_WT_vs_EV_F07.14229.14229.2 0.0342 14-Jul K.AINTFFAK[136.11].N "sp|Q71RC2|LARP4_HUMAN,tr|Q96J85|Q96J85_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 3 918.5055 1.68 57026 14229 2 918.509529 460.26 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 8.8 3045.7 - 1.35E+06 - - - 4.4376 - 1.288 0.346 - 136.2 1 2 0 0.0041 8 0 0 0 7.95E+07 4.74E+07 - - - 2.3586 0.9807 230117_WJC_METTL3_WT_vs_EV_F07.14230.14230.2 0.85 14-Aug K.LLGPVLVK.Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 837.5688 3.82 57027 14230 2 837.569198 419.7917 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 3045.8 - 1.32E+06 - - - 0.505 - 1.278 0.047 - 100 1 2 0 0.0004 8 0 0 0 1.32E+09 3.44E+08 - - - 0.1278 1 230117_WJC_METTL3_WT_vs_EV_F07.14231.14231.2 2.50E-06 26-Sep K.IFVGGLSPDTPEEK[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1495.765 1.43 57028 14231 2 1495.766263 748.8898 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3045.9 - 306141 - - - 0.8611 - 1.928 0.547 - 180.5 1 2 0 0.0013 14 0 0 0 1.45E+07 1.01E+07 - - - 4.7281 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.14234.14234.2 0.115 12-Jul R.FTDILVR[166.11].H sp|O43143|DHX15_HUMAN 1 872.4995 1.08 57029 14234 2 872.500473 437.257 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 3046.3 - 1.36E+07 - - - 1.0888 - 1.467 0.309 - 176 1 2 0 0.0009 7 0 0 0 8.32E+08 7.72E+08 - - - 2.5372 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.14236.14236.2 0.038 16-Dec K.LADMGIAIR[166.11].V sp|Q9Y3I0|RTCB_HUMAN 1 968.5353 1.27 57031 14236 2 968.537737 485.2749 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.84 3046.6 - 2.49E+06 - - - 2.5606 - 2.178 0.185 - 481.6 1 2 0 0.0025 9 0 0 0 3.16E+08 2.48E+08 - - - 2.6586 0.9132 230117_WJC_METTL3_WT_vs_EV_F07.14237.14237.2 0.0522 16-Jul R.VPPEFLVQR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1093.616 1.68 57032 14237 2 1093.625419 547.8153 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3046.7 - 360995 - - - 8.6584 - 1.213 0.299 - 145.5 1 2 0 0.0095 9 0 0 0 4.69E+07 2.79E+07 - - - 1.8051 0.9865 230117_WJC_METTL3_WT_vs_EV_F07.14247.14247.2 0.293 12-Jul R.SLILAMK[136.11].A sp|Q7Z353|HDX_HUMAN 1 782.4815 0.51 57037 14247 2 782.48332 392.248 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 8.47 3048.1 - 1.55E+06 - - - 2.2659 - 1.289 0.076 - 205.4 1 2 0 0.0018 7 0 0 0 2.27E+07 4.47E+07 - - - 0.4062 0.9808 230117_WJC_METTL3_WT_vs_EV_F07.14251.14251.2 3.52 14-Aug K.LLGPVLVK[136.11].Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 845.583 3.82 57039 14251 2 845.583166 423.7988 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 3048.6 - 2.52E+06 - - - 0.2259 - 1.168 0.095 - 108.3 1 2 0 0.0002 8 0 0 0 1.32E+09 3.44E+08 - - - 0.211 0.9908 230117_WJC_METTL3_WT_vs_EV_F07.14262.14262.2 0.319 16-Jul K.LFGETTLVK.S sp|P50748|KNTC1_HUMAN 1 1006.5699 0.94 57045 14262 2 1006.571211 504.2922 Kinetochore-associated protein 1 OS=Homo sapiens OX=9606 GN=KNTC1 PE=1 SV=1 6 3050 - 457443 - - - 1.3044 - 1.258 0.112 - 97.1 1 2 0 0.0013 9 0 0 0 1.30E+07 1.39E+07 - - - 0.5318 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.14263.14263.2 0.0669 22-Dec K.SPILVATAVAAR[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1177.7058 1.13 57046 14263 2 1177.706441 589.8602 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3050.2 - 303995 - - - 0.5205 - 2.429 0.349 - 395.4 1 2 0 0.0006 12 0 0 0 7.02E+08 6.23E+08 - - - 3.9536 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.14266.14266.2 0.536 14-Sep R.LPLATIVK[136.11].D sp|O94776|MTA2_HUMAN 1 861.5779 1.5 57047 14266 2 861.578517 431.7962 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 3050.6 - 1.56E+06 - - - 0.7277 - 1.623 0.258 - 242.8 1 2 0 0.0006 8 0 0 0 3.51E+08 2.34E+08 - - - 2.4069 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.14287.14287.2 0.0211 14-Aug R.LLAMLEQK.N "sp|Q96EA4|SPDLY_HUMAN,tr|H0YBG5|H0YBG5_HUMAN" 2 944.5365 17.53 57058 14287 2 944.53721 473.2755 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 6 3053.1 - 1.20E+06 - - - 0.7633 - 1.538 0.305 - 128.2 1 2 0 0.0007 8 0 0 0 3.78E+07 2.16E+06 - - - 2.5918 0.89 230117_WJC_METTL3_WT_vs_EV_F07.14288.14288.2 1.43 16-May K.VLPLEEAYR.F sp|Q9H223|EHD4_HUMAN 1 1088.5866 2.22 57059 14288 2 1088.590573 545.3006 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 3053.2 - 199510 - - - 3.6405 - 1.124 0.064 - 63.5 6 2 0 0.004 9 0 0 0 2.62E+08 1.18E+08 - - - -0.497 0.9733 230117_WJC_METTL3_WT_vs_EV_F07.14292.14292.2 5.28 12-Jun R.QSILILK.E "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 3 813.5324 2.57 57061 14292 2 813.533048 407.7735 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 8.75 3053.8 - 2.60E+06 - - - 0.8088 - 1.19 0.064 - 123.9 3 2 0 0.0007 7 0 0 0 1.16E+08 4.52E+07 - - - -0.1485 0.9838 230117_WJC_METTL3_WT_vs_EV_F07.14294.14294.2 2.23 14-Aug K.GIGLAIVR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 807.5206 0.93 57062 14294 2 807.521393 404.7676 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 3054 - 589223 - - - 0.9907 - 1.367 0.024 - 165.9 1 2 0 0.0008 8 0 0 0 5.13E+08 5.50E+08 - - - 0.1609 0.94 230117_WJC_METTL3_WT_vs_EV_F07.14302.14302.2 12.2 12-Jun K.IISQLLK[136.11].E "sp|Q9P2P6|STAR9_HUMAN,sp|Q92786|PROX1_HUMAN,tr|C9JU29|C9JU29_HUMAN,tr|U3KPY6|U3KPY6_HUMAN" 4 821.5466 2.58 57067 14302 2 821.547735 411.7806 StAR-related lipid transfer protein 9 OS=Homo sapiens OX=9606 GN=STARD9 PE=1 SV=3 8.75 3054.9 - 1.50E+06 - - - 1.3937 - 1.09 0.025 - 92.7 3 2 0 0.0011 7 0 0 0 1.16E+08 4.52E+07 - - - -0.7148 1 230117_WJC_METTL3_WT_vs_EV_F07.14307.14307.2 0.000325 22-Dec K.SPILVATAVAAR.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1167.6976 1.13 57070 14307 2 1167.698848 584.8561 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 3055.5 - 2.16E+06 - - - 1.1047 - 2.437 0.494 - 586.3 1 2 0 0.0013 12 0 0 0 7.02E+08 6.23E+08 - - - 5.033 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.14318.14318.2 0.00221 14-Sep R.VPDVVLIK.K "sp|Q96D46|NMD3_HUMAN,tr|C9JA08|C9JA08_HUMAN" 2 881.5586 2.31 57078 14318 2 881.559806 441.7866 60S ribosomal export protein NMD3 OS=Homo sapiens OX=9606 GN=NMD3 PE=1 SV=1 5.81 3056.8 - 873250 - - - 1.3624 - 1.457 0.367 - 200.7 1 2 0 0.0012 8 0 0 0 4.08E+07 1.77E+07 - - - 2.8864 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.14331.14331.2 0.00405 16-Sep K.VLPLEEAYR[166.11].F sp|Q9H223|EHD4_HUMAN 1 1098.5949 2.17 57087 14331 2 1098.595505 550.3047 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 3058.3 - 962312 - - - 0.5689 - 1.395 0.272 - 258.8 1 2 0 0.0006 9 0 0 0 2.51E+08 1.16E+08 - - - 2.0129 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.14362.14362.2 0.00156 14-Sep K.VITMFVQR.Q "sp|P13010|XRCC5_HUMAN,tr|C9JZ81|C9JZ81_HUMAN,tr|H7C0H9|H7C0H9_HUMAN" 3 992.5477 0.76 57107 14362 2 992.546372 497.2811 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 9.72 3061.9 - 958857 - - - -1.3601 - 1.947 0.359 - 249.1 1 2 0 -0.0014 8 0 0 0 1.24E+08 1.62E+08 - - - 3.7016 0.996 230117_WJC_METTL3_WT_vs_EV_F07.14368.14368.2 0.443 14-Jul R.LLLIATGK.R "sp|Q9NQW6|ANLN_HUMAN,tr|H7C1K5|H7C1K5_HUMAN" 2 827.548 0.04 57110 14368 2 827.547998 414.7813 Anillin OS=Homo sapiens OX=9606 GN=ANLN PE=1 SV=2 8.75 3062.6 - 1.34E+06 - - - -0.0508 - 1.563 0.149 - 114.4 1 2 0 0 8 0 0 0 4.33E+07 1.15E+09 - - - 1.4884 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.14375.14375.2 0.0661 16-Oct R.LAEYYGLYR.D sp|Q96DV4|RM38_HUMAN 1 1146.571 1.15 57114 14375 2 1146.572167 574.2928 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3063.5 - 790830 - - - 1.0527 - 2.075 0.338 - 395.2 1 2 0 0.0012 9 0 0 0 6.23E+07 5.43E+07 - - - 3.6489 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.14376.14376.2 0.181 16-Nov R.LAEYYGLYR[166.11].D sp|Q96DV4|RM38_HUMAN 1 1156.5792 1.15 57115 14376 2 1156.57848 579.2969 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3063.6 - 535326 - - - -0.6485 - 1.965 0.221 - 527.7 1 2 0 -0.0008 9 0 0 0 6.24E+07 5.43E+07 - - - 2.6273 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.14381.14381.2 0.0149 12-Jul K.LWNGLVK[136.11].V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 836.5 0.95 57118 14381 2 836.499897 419.2573 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 3064.3 - 2.77E+06 - - - -0.0921 - 1.459 0.314 - 99.2 1 2 0 -0.0001 7 0 0 0 9.22E+07 9.72E+07 - - - 2.5571 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.14382.14382.2 0.0119 16-Sep R.VLGVLEVSR.S "sp|Q9H0C8|ILKAP_HUMAN,tr|F8SNU7|F8SNU7_HUMAN,tr|H7C2I8|H7C2I8_HUMAN" 3 970.5811 3.57 57119 14382 2 970.580718 486.2978 Integrin-linked kinase-associated serine\threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1 5.97 3064.4 - 1.27E+06 - - - -0.4255 - 1.579 0.345 - 221.5 1 2 0 -0.0004 9 0 0 0 4.31E+07 1.21E+07 - - - 2.9106 0.994 230117_WJC_METTL3_WT_vs_EV_F07.14384.14384.2 0.0982 12-Jun K.IVQWDIR.S "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 928.5131 1.23 57121 14384 2 928.512527 465.2638 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.84 3064.6 - 598739 - - - -0.5643 - 1.385 0.18 - 80.3 1 2 0 -0.0005 7 0 0 0 1.32E+07 1.08E+07 - - - 1.4023 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.14387.14387.2 0.0675 14-Aug K.VLLSALER[166.11].L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 909.5523 2.54 57122 14387 2 909.553499 455.7834 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.97 3065 - 1.22E+06 - - - 1.3325 - 1.582 0.241 - 176.3 1 2 0 0.0012 8 0 0 0 5.64E+08 2.22E+08 - - - 2.204 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.14389.14389.2 0.0755 12-Aug K.LWNGLVK.V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 828.4858 1.01 57123 14389 2 828.486254 415.2502 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 3065.3 - 1.99E+06 - - - 0.5794 - 1.759 0.324 - 176.1 1 2 0 0.0005 7 0 0 0 9.84E+07 9.73E+07 - - - 3.2233 0.9958 230117_WJC_METTL3_WT_vs_EV_F07.14407.14407.2 2.64 12-Jul K.ALDLLDR.M "sp|P27361|MK03_HUMAN,sp|Q99759|M3K3_HUMAN,tr|H0YEX6|H0YEX6_HUMAN,tr|J3KRN4|J3KRN4_HUMAN,tr|J3QRB6|J3QRB6_HUMAN,tr|B3KR49|B3KR49_HUMAN,tr|E9PQW4|E9PQW4_HUMAN,tr|E9PRH7|E9PRH7_HUMAN,tr|E9PBK7|E9PBK7_HUMAN" 9 814.4549 0.77 57132 14407 2 814.455824 408.2347 Mitogen-activated protein kinase 3 OS=Homo sapiens OX=9606 GN=MAPK3 PE=1 SV=4 4.21 3067.5 - 1.29E+06 - - - 1.1738 - 1.439 0.124 - 149.1 1 2 0 0.001 7 0 0 0 3.36E+07 4.36E+07 - - - 1.1098 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.14408.14408.2 0.0116 16-Jul K.LLVLDPAQR.L sp|P50750|CDK9_HUMAN 1 1023.6077 1.82 57133 14408 2 1023.609174 512.8111 Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3 5.84 3067.6 - 535589 - - - 1.4595 - 1.512 0.272 - 167.3 1 2 0 0.0015 9 0 0 0 5.14E+07 2.82E+07 - - - 2.2456 0.9942 230117_WJC_METTL3_WT_vs_EV_F07.14409.14409.2 0.489 14-Jul K.LGNFFSPK[136.11].V "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 916.4898 0.63 57134 14409 2 916.491137 459.2522 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3067.7 - 1.15E+06 - - - 1.4556 - 1.163 0.186 - 86.7 1 2 0 0.0013 8 0 0 0 4.41E+07 7.00E+07 - - - 0.8698 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.14414.14414.3 5.02E-06 Dec-48 R.LVHPGVAEVVFVK[136.11].K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1400.8271 0.92 57137 14414 3 1400.828902 467.9497 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 3068.3 - 770958 - - - 1.2707 - 2.317 0.412 - 188.2 1 2 0 0.0018 13 0 0 0 1.75E+07 1.89E+07 - - - 5.4111 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.14423.14423.2 0.0562 14-Jul K.VLLSALER.L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 899.544 2.53 57144 14423 2 899.544918 450.7793 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.97 3069.4 - 1.70E+07 - - - 1.0016 - 1.596 0.294 - 181.2 1 2 0 0.0009 8 0 0 0 5.63E+08 2.22E+08 - - - 2.6222 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.14429.14429.2 0.445 14-Aug R.LMTEILGR[166.11].Q "sp|O43809|CPSF5_HUMAN,tr|H3BV41|H3BV41_HUMAN,tr|H3BND3|H3BND3_HUMAN" 3 941.5244 1.92 57148 14429 2 941.525041 471.7695 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3070 - 791920 - - - 0.7254 - 1.51 0.163 - 166.4 1 2 0 0.0007 8 0 0 0 8.63E+07 4.48E+07 - - - 1.4876 0.96 230117_WJC_METTL3_WT_vs_EV_F07.14434.14434.2 4.8 12-Jun K.EIMLGLK.R "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 802.4623 1.57 57151 14434 2 802.462318 402.2384 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.1 3070.6 - 3.05E+06 - - - 0.071 - 1.12 0.05 - 109.2 1 2 0 0.0001 7 0 0 0 8.31E+07 5.28E+07 - - - -0.2306 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.14435.14435.2 0.0117 16-Oct K.LNSLAIGLR.Q sp|P54886|P5CS_HUMAN 1 955.5815 1.57 57152 14435 2 955.582955 478.798 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3070.7 - 1.13E+06 - - - 1.5593 - 2.142 0.4 - 263.8 1 2 0 0.0015 9 0 0 0 6.22E+07 3.96E+07 - - - 4.1987 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.14438.14438.2 0.0972 16-Aug K.LNSLAIGLR[166.11].Q sp|P54886|P5CS_HUMAN 1 965.5897 1.57 57155 14438 2 965.591407 483.8021 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3071 - 769832 - - - 1.7316 - 1.995 0.32 - 184.5 1 2 0 0.0017 9 0 0 0 6.22E+07 3.97E+07 - - - 3.4021 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.14446.14446.2 0.00932 20-Sep K.DAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1160.5561 42.06 57161 14446 2 1160.557855 581.2853 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.92 3071.9 - 351589 - - - 1.5139 - 2.255 0.419 - 254.7 1 2 0 0.0018 11 0 0 0 1.01E+07 2.41E+05 - - - 4.3349 0.9812 230117_WJC_METTL3_WT_vs_EV_F07.14447.14447.2 0.0112 16-Aug K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 11.06 57162 14447 2 1014.541374 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3072 - 309131 - - - 6.7016 - 1.597 0.289 - 131.6 1 2 0 0.0068 9 0 0 0 1.37E+07 1.24E+06 - - - 2.5277 0.8547 230117_WJC_METTL3_WT_vs_EV_F07.14448.14448.2 4.93 16-May R.VPPEFLVQR.A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1083.6077 1.32 57163 14448 2 1083.610545 542.8111 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 3072.1 - 291573 - - - 2.6439 - 1.125 0.002 - 50.4 11 2 0 0.0029 9 0 0 0 6.51E+07 4.91E+07 - - - -1.0696 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.14454.14454.2 0.261 12-Aug K.LSAFAFK.Q sp|O75717|WDHD1_HUMAN 1 782.4327 1.75 57167 14454 2 782.433132 392.2236 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 8.75 3072.8 - 1.65E+06 - - - 0.5828 - 1.711 0.186 - 162 1 2 0 0.0005 7 0 0 0 3.53E+07 2.02E+07 - - - 2.1164 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.14457.14457.2 0.00844 18-Dec K.LPAVVTADLR.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1053.6182 2.13 57170 14457 2 1053.618865 527.8164 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.84 3073.1 - 811457 - - - 0.5884 - 2.445 0.322 - 555.7 1 2 0 0.0006 10 0 0 0 5.82E+07 2.74E+07 - - - 3.9146 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.14458.14458.2 1.32E-05 28-Nov R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 0.46 57171 14458 2 1410.786371 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3073.2 - 195712 - - - 2.3342 - 2.145 0.481 - 220.4 1 2 0 0.0033 15 0 0 0 1.16E+07 2.55E+07 - - - 4.4688 0.999 230117_WJC_METTL3_WT_vs_EV_F07.14482.14482.2 0.0651 12-Aug R.FLDPEFR.E sp|Q5VUA4|ZN318_HUMAN 1 922.4549 1.67 57184 14482 2 922.456382 462.2347 Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2 4.37 3075.9 - 2.57E+06 - - - 1.6413 - 1.49 0.278 - 242.3 1 2 0 0.0015 7 0 0 0 6.02E+07 3.60E+07 - - - 2.3574 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.14486.14486.2 0.0135 18-Sep K.IMLVEPPVAK[136.11].V sp|P18583|SON_HUMAN 1 1103.6504 1.6 57188 14486 2 1103.653267 552.8325 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3076.4 - 289835 - - - 2.595 - 1.663 0.158 - 146 1 2 0 0.0029 10 0 0 0 1.46E+07 9.17E+06 - - - 1.6268 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.14492.14492.2 1.37 12-Aug R.VLGLLER.S "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 798.4963 1.5 57192 14492 2 798.497314 400.2554 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 5.97 3077 - 1.97E+06 - - - 1.221 - 1.512 0.163 - 219.7 1 2 0 0.001 7 0 0 0 8.13E+07 5.42E+07 - - - 1.5546 1 230117_WJC_METTL3_WT_vs_EV_F07.14493.14493.2 0.000106 18-Nov R.IATANMLGIR.K sp|Q9NX20|RM16_HUMAN 1 1058.5907 1.01 57193 14493 2 1058.594497 530.3026 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3077.2 - 402330 - - - 3.6341 - 2.482 0.434 - 367.6 1 2 0 0.0038 10 0 0 0 6.62E+07 6.55E+07 - - - 4.7828 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.14494.14494.2 0.0204 18-Nov R.IATANMLGIR[166.11].K sp|Q9NX20|RM16_HUMAN 1 1068.5989 1.08 57194 14494 2 1068.601932 535.3067 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3077.3 - 362758 - - - 2.8186 - 1.927 0.321 - 366.5 1 2 0 0.003 10 0 0 0 6.62E+07 6.13E+07 - - - 3.242 0.999 230117_WJC_METTL3_WT_vs_EV_F07.14501.14501.2 8.70E-05 26-Oct K.VPQVSTPTLVEVSR.N "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1510.8355 999 57198 14501 2 1510.841613 756.425 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.97 3078.2 - 175569 - - - 4.0408 - 2.102 0.468 - 301.5 1 2 0 0.0061 14 0 0 0 3.02E+06 0.00E+00 - - - 4.36 0.9362 230117_WJC_METTL3_WT_vs_EV_F07.14509.14509.2 1.09 16-Jun K.EVLVLTSVR.N sp|Q13371|PHLP_HUMAN 1 1014.6073 0.36 57201 14509 2 1014.610237 508.3109 Phosducin-like protein OS=Homo sapiens OX=9606 GN=PDCL PE=1 SV=3 6.1 3079.3 - 296346 - - - 2.8494 - 1.269 0.014 - 68.4 4 2 0 0.0029 9 0 0 0 5.95E+06 1.66E+07 - - - -0.4362 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.14518.14518.2 0.0262 16-Oct R.ILALDC[160.03]GLK[136.11].Y "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1009.5722 1.38 57206 14518 2 1009.574756 505.7934 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.83 3080.5 - 2.00E+06 - - - 2.5783 - 2.013 0.267 - 265 1 2 0 0.0026 9 0 0 0 1.06E+08 7.66E+07 - - - 3.0363 0.9808 230117_WJC_METTL3_WT_vs_EV_F07.14522.14522.2 2.11 16-Oct R.AGVIFPVGR[166.11].L "sp|Q9P0M6|H2AW_HUMAN,sp|O75367|H2AY_HUMAN,tr|A0A7I2YQD6|A0A7I2YQD6_HUMAN,tr|B4DJC3|B4DJC3_HUMAN,tr|A0A7I2V412|A0A7I2V412_HUMAN,tr|Q5SQT3|Q5SQT3_HUMAN,tr|A0A7I2V423|A0A7I2V423_HUMAN,tr|A0A7I2V2N7|A0A7I2V2N7_HUMAN,tr|A0A7I2V4D9|A0A7I2V4D9_HUMAN,tr|D6RCF2|D6RCF2_HUMAN,tr|A0A7I2V6E9|A0A7I2V6E9_HUMAN,tr|A0A7I2YQB9|A0A7I2YQB9_HUMAN,tr|A0A7I2YQR8|A0A7I2YQR8_HUMAN" 13 924.5421 0.6 57209 14522 2 924.543986 463.2783 Core histone macro-H2A.2 OS=Homo sapiens OX=9606 GN=MACROH2A2 PE=1 SV=3 9.79 3080.9 - 698678 - - - 2.0864 - 1.44 0.003 - 273.5 1 2 0 0.0019 9 0 0 0 8.10E+07 1.34E+08 - - - 0.1175 0.9923 230117_WJC_METTL3_WT_vs_EV_F07.14523.14523.2 0.0613 14-Jun K.LLEPALSQ.- sp|Q05932|FOLC_HUMAN 1 869.4858 - 57210 14523 2 869.488504 435.7502 "Folylpolyglutamate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=FPGS PE=1 SV=3" 4 3081 - 582114 - - - 3.0708 - 1.18 0.216 - 68.5 1 2 0 0.0027 8 0 0 0 - - - - - 1.1347 0.9952 230117_WJC_METTL3_WT_vs_EV_F07.14531.14531.2 0.133 14-Aug K.VPGIFISR[166.11].M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 897.5312 0.08 57214 14531 2 897.533006 449.7729 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3082.1 - 1.44E+06 - - - 2.059 - 1.554 0.1 - 209.8 1 2 0 0.0018 8 0 0 0 4.25E+07 5.19E+08 - - - 1.1085 0.9889 230117_WJC_METTL3_WT_vs_EV_F07.14533.14533.2 0.65 14-Aug R.IGFIEEVK.A sp|Q96P63|SPB12_HUMAN 1 933.5171 23.6 57216 14533 2 933.519368 467.7658 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 4.53 3082.2 - 1.40E+06 - - - 2.3931 - 1.245 0.12 - 119.1 1 2 0 0.0022 8 0 0 0 2.60E+08 1.10E+07 - - - 0.5875 0.9943 230117_WJC_METTL3_WT_vs_EV_F07.14539.14539.2 0.0331 14-Aug K.VPGIFISR.M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 887.5229 0.39 57220 14539 2 887.524649 444.7687 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3082.9 - 2.82E+06 - - - 1.9842 - 1.567 0.076 - 207 1 2 0 0.0018 8 0 0 0 1.37E+08 3.55E+08 - - - 0.9564 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.14545.14545.2 0.0504 16-Aug R.VLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 969.5859 1.43 57224 14545 2 969.589651 485.8002 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3083.5 - 1.51E+06 - - - 3.8872 - 1.841 0.307 - 158.5 1 2 0 0.0038 9 0 0 0 1.25E+09 8.70E+08 - - - 3.073 0.9835 230117_WJC_METTL3_WT_vs_EV_F07.14546.14546.2 0.198 12-Aug R.VVEFLVK.H sp|P42773|CDN2C_HUMAN 1 832.5058 2.12 57225 14546 2 832.509095 417.2602 Cyclin-dependent kinase 4 inhibitor C OS=Homo sapiens OX=9606 GN=CDKN2C PE=1 SV=1 5.97 3083.6 - 1.52E+06 - - - 3.9087 - 1.248 0.166 - 149.5 1 2 0 0.0033 7 0 0 0 4.33E+07 2.04E+07 - - - 0.968 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.14547.14547.2 0.000255 16-Oct K.MYLQAAIVR.L "sp|Q13617|CUL2_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 2 1063.5848 2.53 57226 14547 2 1063.586549 532.7997 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 8.5 3083.7 - 934062 - - - 1.6106 - 1.756 0.487 - 365.7 1 2 0 0.0017 9 0 0 0 1.96E+07 7.73E+06 - - - 4.2663 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.14548.14548.2 0.00145 18-Jul K.LFPGSPAIYK.L "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|F8W705|F8W705_HUMAN,tr|C9JF75|C9JF75_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|C9J6W1|C9J6W1_HUMAN,tr|H0YBN8|H0YBN8_HUMAN,tr|C9J1W9|C9J1W9_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 17 1091.6015 1.88 57227 14548 2 1091.604626 546.808 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 8.59 3083.9 - 714364 - - - 2.8344 - 1.431 0.372 - 127.5 1 2 0 0.0031 10 0 0 0 2.91E+07 1.55E+07 - - - 2.7879 0.9958 230117_WJC_METTL3_WT_vs_EV_F07.14549.14549.2 0.012 16-Aug R.FLAEEGFYK.F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1102.5335 1.24 57228 14549 2 1102.538665 552.274 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3084 - 711605 - - - 4.6738 - 1.259 0.405 - 137.2 1 2 0 0.0052 9 0 0 0 1.79E+08 1.45E+08 - - - 2.697 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.14550.14550.2 0.0442 16-Sep R.FLAEEGFYK[136.11].F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1110.5477 1.24 57229 14550 2 1110.550455 556.2811 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3084.1 - 396089 - - - 2.47 - 1.659 0.365 - 202.7 1 2 0 0.0027 9 0 0 0 1.79E+08 1.45E+08 - - - 3.2005 0.9386 230117_WJC_METTL3_WT_vs_EV_F07.14551.14551.2 1.5 18-Apr R.SLVVPAYAYR.K sp|Q9Y3R4|NEUR2_HUMAN 1 1137.6182 70.66 57230 14551 2 1137.620682 569.8164 Sialidase-2 OS=Homo sapiens OX=9606 GN=NEU2 PE=1 SV=2 8.31 3084.3 - 227998 - - - 2.1422 - 1.164 0.052 - 45.6 12 2 0 0.0024 10 0 0 0 4.58E+06 6.49E+04 - - - -0.6339 0.996 230117_WJC_METTL3_WT_vs_EV_F07.14552.14552.2 0.127 20-Jun M.VPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1175.7278 2.83 57231 14552 2 1175.728558 588.8712 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.72 3084.4 - 204434 - - - 0.649 - 1.363 0.213 - 76.8 3 2 0 0.0008 11 0 0 0 3.11E+07 1.10E+07 - - - 1.2386 0.9919 230117_WJC_METTL3_WT_vs_EV_F07.14556.14556.2 7.63 12-May K.RIYGGFK[136.11].S sp|Q14520|HABP2_HUMAN 1 847.4796 - 57233 14556 2 847.479583 424.7471 Hyaluronan-binding protein 2 OS=Homo sapiens OX=9606 GN=HABP2 PE=1 SV=1 9.99 3084.9 - 1.87E+06 - - - 0.0118 - 1.219 0.203 - 70 4 2 0 0 7 0 0 0 - - - - - 0.8989 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.14557.14557.2 0.00725 12-Sep R.IAAYLFK.G "sp|Q00610|CLH1_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|J3KRF5|J3KRF5_HUMAN" 5 824.4796 1 57234 14557 2 824.480629 413.2471 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.59 3085 - 1.17E+06 - - - 1.2165 - 1.946 0.287 - 219.5 1 2 0 0.001 7 0 0 0 6.60E+08 6.58E+08 - - - 3.27 0.9251 230117_WJC_METTL3_WT_vs_EV_F07.14558.14558.2 0.0555 14-Aug M.PTPVILLK.E "sp|Q99832|TCPH_HUMAN,tr|A0A0D9SG95|A0A0D9SG95_HUMAN,tr|F8WBP8|F8WBP8_HUMAN" 3 879.5793 12.18 57235 14558 2 879.580863 440.7969 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 9.18 3085.1 - 1.23E+06 - - - 1.7315 - 1.396 0.319 - 189.1 1 1 0 0.0015 8 0 0 0 2.64E+08 2.16E+07 - - - 2.4028 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.14559.14559.2 0.0555 16-Sep K.TLAIELAPR[166.11].N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 992.5894 1.03 57236 14559 2 992.590539 497.302 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3085.2 - 898220 - - - 1.1465 - 1.908 0.314 - 309.5 1 2 0 0.0011 9 0 0 0 2.29E+09 2.23E+09 - - - 3.2289 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.14562.14562.2 0.00978 20-Jul K.LIPGPLSPVAR[166.11].G sp|P48634|PRC2A_HUMAN 1 1128.6894 1.22 57239 14562 2 1128.693102 565.352 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3085.5 - 248968 - - - 3.2365 - 1.519 0.324 - 142.7 1 2 0 0.0037 11 0 0 0 8.67E+08 7.11E+08 - - - 2.5638 0.9861 230117_WJC_METTL3_WT_vs_EV_F07.14565.14565.2 1.03 12-Jun K.LPNLLGR[166.11].A sp|Q9Y512|SAM50_HUMAN 1 791.4893 1.54 57240 14565 2 791.490474 396.7519 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 9.75 3085.9 - 864662 - - - 1.4921 - 1.226 0.105 - 68.2 3 2 0 0.0012 7 0 0 0 4.09E+07 2.66E+07 - - - 0.2486 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.14569.14569.2 0.00515 18-Jul K.FMQASEDLLK[136.11].E "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 1188.594 5.46 57244 14569 2 1188.596244 595.3043 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.37 3086.3 - 243750 - - - 1.8795 - 1.4 0.384 - 114.6 1 2 0 0.0022 10 0 0 0 3.19E+07 5.85E+06 - - - 2.8157 0.9926 230117_WJC_METTL3_WT_vs_EV_F07.14571.14571.2 0.00497 18-Aug K.WTLLQEQGTK.T "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1202.6295 5.3 57246 14571 2 1202.628812 602.322 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6 3086.6 - 187915 - - - -0.6037 - 1.64 0.111 - 162.6 1 2 0 -0.0007 10 0 0 0 3.80E+06 7.18E+05 - - - 1.2415 0.9947 230117_WJC_METTL3_WT_vs_EV_F07.14575.14575.2 20 12-Sep K.IGIEIIK.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 784.5058 2.02 57249 14575 2 784.506794 393.2602 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3087 - 1.57E+06 - - - 1.2148 - 1.895 0 - 197 2 2 0 0.001 7 0 0 0 2.33E+10 1.15E+10 - - - 0.9316 0.999 230117_WJC_METTL3_WT_vs_EV_F07.14578.14578.2 0.122 18-Oct K.LPAVVTADLR[166.11].L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1063.6265 2.25 57250 14578 2 1063.627086 532.8205 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.84 3087.4 - 1.12E+06 - - - 0.5368 - 1.958 0.217 - 382.8 1 2 0 0.0006 10 0 0 0 1.02E+08 4.55E+07 - - - 2.5191 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.14582.14582.2 0.000291 20-Oct K.LIPGPLSPVAR.G sp|P48634|PRC2A_HUMAN 1 1118.6812 1.22 57252 14582 2 1118.682181 560.3479 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3087.9 - 1.02E+06 - - - 0.8957 - 1.763 0.483 - 383.1 1 2 0 0.001 11 0 0 0 8.67E+08 7.11E+08 - - - 4.142 0.9332 230117_WJC_METTL3_WT_vs_EV_F07.14583.14583.2 0.862 12-Aug K.VWDVIGR[166.11].S "sp|O14618|CCS_HUMAN,tr|J3KNF4|J3KNF4_HUMAN,tr|E9PP76|E9PP76_HUMAN" 3 853.4686 4.29 57253 14583 2 853.465462 427.7416 Copper chaperone for superoxide dismutase OS=Homo sapiens OX=9606 GN=CCS PE=1 SV=1 5.81 3088 - 193447 - - - -3.6264 - 1.439 0.106 - 148.3 1 2 0 -0.0031 7 0 0 0 5.42E+07 1.26E+07 - - - 0.9761 0.9907 230117_WJC_METTL3_WT_vs_EV_F07.14584.14584.2 1.19 12-Jul K.MLPTFVR[166.11].A "sp|Q2TB90|HKDC1_HUMAN,sp|P52790|HXK3_HUMAN,sp|P19367|HXK1_HUMAN,sp|P52789|HXK2_HUMAN,tr|E9PB90|E9PB90_HUMAN,tr|B1AR62|B1AR62_HUMAN" 6 872.4818 1.88 57254 14584 2 872.483278 437.2482 Hexokinase HKDC1 OS=Homo sapiens OX=9606 GN=HKDC1 PE=1 SV=3 9.5 3088.1 - 585614 - - - 1.7341 - 1.404 0.077 - 128.6 2 2 0 0.0015 7 0 0 0 6.30E+07 3.35E+07 - - - 0.5499 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.14592.14592.2 0.000202 14-Sep K.QFFVAVER[166.11].E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1004.5319 0.93 57258 14592 2 1004.531762 503.2732 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 6 3089.2 - 1.43E+06 - - - -0.1234 - 1.607 0.4 - 359 1 2 0 -0.0001 8 0 0 0 1.00E+08 1.07E+08 - - - 3.426 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.14594.14594.2 0.0592 20-Jul K.ILATTPSAVFR[166.11].V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1184.6793 2.11 57260 14594 2 1184.680125 593.3469 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3089.4 - 239874 - - - 0.7141 - 1.42 0.348 - 111.2 1 2 0 0.0008 11 0 0 0 1.07E+08 5.09E+07 - - - 2.5597 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.14598.14598.2 0.00628 20-Oct K.ILATTPSAVFR.V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1174.671 2.11 57262 14598 2 1174.673358 588.3428 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3089.9 - 758994 - - - 1.9997 - 1.688 0.352 - 264.8 1 2 0 0.0023 11 0 0 0 1.07E+08 5.09E+07 - - - 3.0564 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.14599.14599.2 0.00305 18-Aug K.IMLVEPPVAK.V sp|P18583|SON_HUMAN 1 1095.6362 1.58 57263 14599 2 1095.637263 548.8254 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3090.1 - 1.14E+06 - - - 0.9675 - 1.895 0.337 - 197.9 1 2 0 0.0011 10 0 0 0 7.78E+07 4.93E+07 - - - 3.314 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.14612.14612.2 0.112 14-Aug R.ELVITIAR[166.11].E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 923.5679 1.27 57269 14612 2 923.567718 462.7912 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3091.7 - 3.84E+06 - - - -0.2371 - 1.401 0.226 - 216.1 1 2 0 -0.0002 8 0 0 0 2.92E+08 2.31E+08 - - - 1.7271 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.14616.14616.2 0.00404 14-Jul K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 0.99 57271 14616 2 895.481125 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3092.1 - 720319 - - - 0.861 - 1.34 0.357 - 120.1 1 2 0 0.0008 8 0 0 0 8.91E+07 9.01E+07 - - - 2.5602 0.9788 230117_WJC_METTL3_WT_vs_EV_F07.14617.14617.2 1.52 12-Aug R.LLQYLYK.Q sp|P48723|HSP13_HUMAN 1 939.543 2.25 57272 14617 2 939.542874 470.7788 Heat shock 70 kDa protein 13 OS=Homo sapiens OX=9606 GN=HSPA13 PE=1 SV=1 8.5 3092.3 - 694064 - - - -0.0851 - 1.31 0.048 - 151.8 1 2 0 -0.0001 7 0 0 0 2.78E+07 1.24E+07 - - - 0.2511 0.9891 230117_WJC_METTL3_WT_vs_EV_F07.14618.14618.2 0.638 14-Aug R.GLVGEIIK.R "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 827.5117 0.99 57273 14618 2 827.511918 414.7631 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6 3092.3 - 1.75E+07 - - - 0.319 - 1.27 0.11 - 213 1 2 0 0.0003 8 0 0 0 7.43E+09 7.48E+09 - - - 0.5742 0.9953 230117_WJC_METTL3_WT_vs_EV_F07.14644.14644.2 0.219 14-Aug R.ELVITIAR.E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 913.5597 1.27 57286 14644 2 913.558334 457.7871 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3095.4 - 6.98E+06 - - - -1.4591 - 1.644 0.213 - 367.3 1 2 0 -0.0013 8 0 0 0 2.92E+08 2.31E+08 - - - 2.1131 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.14664.14664.2 0.000865 16-Sep R.VYSYALALK.H "sp|Q9UKK9|NUDT5_HUMAN,tr|A6NFX8|A6NFX8_HUMAN" 2 1026.575 3.04 57296 14664 2 1026.575399 514.2948 ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1 8.47 3097.8 - 1.26E+06 - - - 0.4052 - 1.457 0.415 - 204.5 1 2 0 0.0004 9 0 0 0 6.15E+07 2.03E+07 - - - 3.1949 1 230117_WJC_METTL3_WT_vs_EV_F07.14666.14666.2 2.54E-08 16-Nov R.GSPLLIGVR.S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 910.56 1.64 57297 14666 2 910.559058 456.2873 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3098 - 9.86E+06 - - - -1.0367 - 2.155 0.452 - 524.5 1 2 0 -0.0009 9 0 0 0 3.36E+08 2.05E+08 - - - 4.6004 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.14668.14668.2 0.0639 16-Nov R.GSPLLIGVR[166.11].S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 920.5683 1.64 57298 14668 2 920.567 461.2914 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3098.3 - 6.11E+06 - - - -1.3818 - 2.261 0.406 - 556.1 1 2 0 -0.0013 9 0 0 0 3.35E+08 2.04E+08 - - - 4.3995 0.9917 230117_WJC_METTL3_WT_vs_EV_F07.14679.14679.2 0.0738 12-Jul R.IFFVSAK.E "sp|O95140|MFN2_HUMAN,sp|Q8IWA4|MFN1_HUMAN,tr|A0A6Q8PGV8|A0A6Q8PGV8_HUMAN,tr|H7C5H5|H7C5H5_HUMAN,tr|A0A6Q8PFJ4|A0A6Q8PFJ4_HUMAN,tr|A0A6Q8PGA3|A0A6Q8PGA3_HUMAN,tr|A0A6Q8PGS9|A0A6Q8PGS9_HUMAN" 7 810.464 0.57 57303 14679 2 810.462219 406.2393 Mitofusin-2 OS=Homo sapiens OX=9606 GN=MFN2 PE=1 SV=3 8.75 3099.6 - 1.46E+06 - - - -2.1679 - 1.469 0.237 - 158.8 1 2 0 -0.0018 7 0 0 0 3.14E+07 5.56E+07 - - - 2.0095 0.9927 230117_WJC_METTL3_WT_vs_EV_F07.14684.14684.2 6.18 12-Jul R.ELLEIVK.K sp|P31153|METK2_HUMAN 1 842.5113 1.22 57305 14684 2 842.51037 422.2629 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 4.53 3100.2 - 2.09E+06 - - - -1.1276 - 1.64 0.124 - 182.9 1 2 0 -0.0009 7 0 0 0 8.36E+07 6.86E+07 - - - 1.524 0.9957 230117_WJC_METTL3_WT_vs_EV_F07.14686.14686.2 0.206 16-Aug K.FVGNIYTLK[136.11].C "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1061.6001 2.02 57306 14686 2 1061.598768 531.8073 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3100.5 - 1.82E+06 - - - -1.2378 - 1.411 0.274 - 136.2 1 2 0 -0.0013 9 0 0 0 1.57E+08 7.79E+07 - - - 2.0604 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.14690.14690.2 0.00471 16-Oct K.FVGNIYTLK.C "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1053.5859 2.02 57309 14690 2 1053.586025 527.8002 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3100.9 - 3.43E+06 - - - 0.1357 - 1.552 0.301 - 238.1 1 2 0 0.0001 9 0 0 0 1.57E+08 7.79E+07 - - - 2.5358 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.14694.14694.2 0.0119 16-Sep R.EVIAGPLLR.N "sp|Q6DKJ4|NXN_HUMAN,tr|I3L4V6|I3L4V6_HUMAN" 2 966.5862 0.1 57312 14694 2 966.584526 484.3004 Nucleoredoxin OS=Homo sapiens OX=9606 GN=NXN PE=1 SV=2 6.1 3101.4 - 831758 - - - -1.7484 - 1.598 0.311 - 213.3 1 2 0 -0.0017 9 0 0 0 4.11E+07 4.00E+08 - - - 2.6936 0.9957 230117_WJC_METTL3_WT_vs_EV_F07.14695.14695.2 0.836 14-Sep R.YADLLLEK[136.11].E sp|Q99459|CDC5L_HUMAN 1 971.5419 1.19 57313 14695 2 971.540907 486.7782 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3101.5 - 1.55E+06 - - - -1.02 - 1.505 0.225 - 170.1 1 2 0 -0.001 8 0 0 0 4.62E+08 3.89E+08 - - - 1.9354 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.14696.14696.2 0.348 16-Jul R.EVIAGPLLR[166.11].N "sp|Q6DKJ4|NXN_HUMAN,tr|I3L4V6|I3L4V6_HUMAN" 2 976.5945 0.09 57314 14696 2 976.595994 489.3045 Nucleoredoxin OS=Homo sapiens OX=9606 GN=NXN PE=1 SV=2 6.1 3101.6 - 470328 - - - 1.5441 - 1.325 0.196 - 67.3 1 2 0 0.0015 9 0 0 0 4.14E+07 4.61E+08 - - - 1.3023 0.9929 230117_WJC_METTL3_WT_vs_EV_F07.14701.14701.2 1.26 12-Jul R.ELLEIVK[136.11].K sp|P31153|METK2_HUMAN 1 850.5255 1.23 57317 14701 2 850.524661 426.27 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 4.53 3102.3 - 3.32E+06 - - - -1.01 - 1.613 0.126 - 197.9 1 2 0 -0.0009 7 0 0 0 8.30E+07 6.73E+07 - - - 1.4862 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.14702.14702.2 0.448 14-Oct R.YADLLLEK.E sp|Q99459|CDC5L_HUMAN 1 963.5277 1.19 57318 14702 2 963.528532 482.7711 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3102.4 - 3.75E+06 - - - 0.8656 - 1.642 0.273 - 248.3 1 2 0 0.0008 8 0 0 0 4.63E+08 3.90E+08 - - - 2.5528 0.9546 230117_WJC_METTL3_WT_vs_EV_F07.14704.14704.2 0.77 12-Jul R.TLDTFLR[166.11].S sp|Q96SK2|TM209_HUMAN 1 874.4788 1.67 57320 14704 2 874.477845 438.2467 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 5.5 3102.5 - 2.22E+06 - - - -1.0784 - 1.095 0.109 - 149 1 2 0 -0.0009 7 0 0 0 8.50E+07 5.08E+07 - - - 0.1333 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.14710.14710.2 0.000191 16-Sep R.MGPNIYELR.T "sp|Q9BPW8|NIPS1_HUMAN,tr|C9JDV8|C9JDV8_HUMAN,tr|H7C2U6|H7C2U6_HUMAN" 3 1091.5434 1.55 57324 14710 2 1091.544215 546.779 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.75 3103.2 - 713718 - - - 0.7787 - 1.962 0.399 - 405 1 2 0 0.0008 9 0 0 0 7.99E+07 5.16E+07 - - - 3.9376 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.14714.14714.2 0.000124 20-Sep K.LLAQQLVSPVK.W sp|Q8IVS2|FABD_HUMAN 1 1194.7336 6.01 57326 14714 2 1194.733933 598.3741 "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Homo sapiens OX=9606 GN=MCAT PE=1 SV=2" 8.75 3103.7 - 129602 - - - 0.2712 - 1.892 0.435 - 174.2 1 2 0 0.0003 11 0 0 0 2.73E+06 4.54E+05 - - - 3.9788 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.14715.14715.2 0.0388 16-Sep K.LVTEPLVLK[136.11].S sp|O43896|KIF1C_HUMAN 1 1018.6518 1.2 57327 14715 2 1018.655703 510.3332 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 6 3103.9 - 1.04E+06 - - - 3.8482 - 1.832 0.294 - 180.2 1 2 0 0.0039 9 0 0 0 4.87E+07 4.04E+07 - - - 2.9627 0.859 230117_WJC_METTL3_WT_vs_EV_F07.14721.14721.2 0.387 12-Aug S.EEIDQLR.G sp|Q9H2D6|TARA_HUMAN 1 901.4505 1.93 57331 14721 2 901.451459 451.7325 TRIO and F-actin-binding protein OS=Homo sapiens OX=9606 GN=TRIOBP PE=1 SV=3 4.14 3104.6 - 1.24E+06 - - - 1.0516 - 1.624 0.153 - 290.6 1 1 0 0.0009 7 0 0 0 5.45E+07 2.83E+07 - - - 1.7072 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.14728.14728.2 9.46E-05 14-Aug R.EFADFEYR.K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1075.4611 1.26 57336 14728 2 1075.461844 538.7378 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3105.6 - 681879 - - - 0.715 - 1.827 0.491 - 298.6 1 2 0 0.0008 8 0 0 0 2.64E+07 2.09E+07 - - - 4.4849 0.98 230117_WJC_METTL3_WT_vs_EV_F07.14730.14730.2 0.106 12-Sep R.LMDLLQK[136.11].K sp|Q9UJV9|DDX41_HUMAN 1 867.4979 0.91 57338 14730 2 867.498497 434.7562 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.84 3105.8 - 2.23E+06 - - - 0.6594 - 1.381 0.001 - 216.7 1 2 0 0.0006 7 0 0 0 8.37E+07 9.15E+07 - - - 0.071 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.14731.14731.2 0.129 14-Jul R.EFADFEYR[166.11].K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1085.4693 1.26 57339 14731 2 1085.469815 543.7419 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3105.9 - 547948 - - - 0.433 - 1.451 0.296 - 213.7 1 2 0 0.0005 8 0 0 0 2.64E+07 2.09E+07 - - - 2.3498 0.8817 230117_WJC_METTL3_WT_vs_EV_F07.14740.14740.2 1.93 14-Aug E.PGILVATK.D sp|Q9NZH4|PTTG3_HUMAN 1 797.5011 1.44 57344 14740 2 797.501936 399.7578 Putative pituitary tumor-transforming gene 3 protein OS=Homo sapiens OX=9606 GN=PTTG3P PE=5 SV=1 9.18 3107 - 988425 - - - 1.0608 - 1.674 0.175 - 146 1 1 0 0.0008 8 0 0 0 2.61E+07 1.81E+07 - - - 1.8872 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.14741.14741.2 0.00869 18-Oct K.GVAYTLLTPK[136.11].D "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1069.6263 2.58 57345 14741 2 1069.628239 535.8204 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.59 3107.1 - 573763 - - - 1.8156 - 1.498 0.262 - 241.3 1 2 0 0.0019 10 0 0 0 5.60E+07 2.17E+07 - - - 2.1036 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.14743.14743.2 0.0731 14-Jul K.IIYIAPMR[166.11].S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 985.5658 1.38 57347 14743 2 985.567215 493.7902 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 3107.2 - 1.65E+06 - - - 1.4063 - 1.448 0.243 - 137.4 1 2 0 0.0014 8 0 0 0 1.69E+08 1.23E+08 - - - 1.9518 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.14755.14755.2 0.217 12-Jul K.VSTVFWK.S sp|Q14152|EIF3A_HUMAN 1 865.4698 0.69 57353 14755 2 865.470821 433.7422 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.72 3108.7 - 1.11E+06 - - - 1.1913 - 1.309 0.261 - 137 1 2 0 0.001 7 0 0 0 7.13E+07 1.03E+08 - - - 1.8216 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.14762.14762.2 0.00302 12-Sep R.TMLLLSR.S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 832.4841 2 57357 14762 2 832.484821 417.2493 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.41 3109.6 - 4.71E+06 - - - 0.9153 - 1.672 0.258 - 410.7 1 2 0 0.0008 7 0 0 0 1.47E+08 7.35E+07 - - - 2.5751 0.878 230117_WJC_METTL3_WT_vs_EV_F07.14769.14769.2 0.0752 18-Jun R.IINEPTAAAI.A "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 16 1011.5601 - 57360 14769 2 1011.561674 506.7873 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4 3110.5 - 2.04E+06 - - - 1.5946 - 1.216 0.307 - 57 1 1 0 0.0016 10 0 0 0 - - - - - 1.8539 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.14771.14771.2 0.00146 18-Sep R.VVVDALSGLK[136.11].G "sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|F8WCN3|F8WCN3_HUMAN" 3 1007.6106 1.82 57362 14771 2 1007.612519 504.8126 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 5.81 3110.7 - 2.39E+06 - - - 1.8579 - 1.886 0.36 - 256.5 1 2 0 0.0019 10 0 0 0 1.16E+08 6.39E+07 - - - 3.4703 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.14776.14776.2 0.0946 16-Aug K.LGIIGVVNR.S "sp|O00429|DNM1L_HUMAN,tr|F8VZ52|F8VZ52_HUMAN" 2 939.5866 1.47 57365 14776 2 939.587296 470.8006 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 9.75 3111.2 - 2.27E+06 - - - 0.7929 - 1.673 0.279 - 137.1 1 2 0 0.0007 9 0 0 0 9.03E+07 6.13E+07 - - - 2.5903 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.14777.14777.2 0.0229 14-Jun K.LLESDYFR.Y "sp|Q96HE7|ERO1A_HUMAN,tr|G3V503|G3V503_HUMAN,tr|G3V3E6|G3V3E6_HUMAN" 3 1041.5131 1.75 57366 14777 2 1041.511465 521.7638 ERO1-like protein alpha OS=Homo sapiens OX=9606 GN=ERO1A PE=1 SV=2 4.37 3111.4 - 613516 - - - -1.5804 - 1.376 0.349 - 93.3 1 2 0 -0.0016 8 0 0 0 2.31E+07 1.32E+07 - - - 2.5808 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.14796.14796.2 0.000843 16-Nov R.VLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 11 1028.5866 9014.8 57376 14796 2 1028.588371 515.3006 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3113.5 - 5.57E+06 - - - 1.7121 - 2.221 0.414 - 487.5 1 2 0 0.0018 9 0 0 0 2.90E+09 3.22E+05 - - - 4.4068 0.999 230117_WJC_METTL3_WT_vs_EV_F07.14801.14801.2 0.00282 14-Aug R.LGYPVLVR[166.11].A "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 925.5625 2.08 57379 14801 2 925.565324 463.7885 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 8.75 3114.1 - 3.00E+06 - - - 3.0965 - 1.601 0.369 - 167.9 1 2 0 0.0029 8 0 0 0 3.27E+08 1.57E+08 - - - 3.1849 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.14811.14811.2 0.00247 12-Jul K.FDLMYAK.R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 886.4259 3.24 57385 14811 2 886.428161 444.2202 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3115.3 - 1.85E+06 - - - 2.5778 - 1.372 0.231 - 148.5 1 2 0 0.0023 7 0 0 0 1.36E+09 4.21E+08 - - - 1.7486 0.96 230117_WJC_METTL3_WT_vs_EV_F07.14820.14820.2 0.142 14-Jun K.LTPLLSVR[166.11].E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 907.573 0.92 57391 14820 2 907.574344 454.7938 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3116.4 - 5.63E+06 - - - 1.4555 - 1.142 0.033 - 150.1 2 2 0 0.0013 8 0 0 0 3.44E+08 3.76E+08 - - - -0.4497 0.8472 230117_WJC_METTL3_WT_vs_EV_F07.14826.14826.3 0.00252 Nov-56 K.VGEVIVTKDDAMLLK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1629.9011 6.68 57395 14826 3 1629.899697 544.3077 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3117.1 - 361231 - - - -0.8884 - 2.128 0.238 - 48 1 2 1 -0.0014 15 0 0 0 4.92E+06 7.37E+05 - - - 3.1636 0.9824 230117_WJC_METTL3_WT_vs_EV_F07.14830.14830.2 9.52 12-Jun K.IGIEIIK.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 784.5058 2.02 57398 14830 2 784.506403 393.2602 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3117.6 - 3.01E+06 - - - 0.7164 - 1.43 0.014 - 78.6 2 2 0 0.0006 7 0 0 0 2.33E+10 1.15E+10 - - - 0.1431 0.9946 230117_WJC_METTL3_WT_vs_EV_F07.14832.14832.2 0.0418 14-Jun K.LTPLLSVR.E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 897.5648 0.92 57399 14832 2 897.565741 449.7897 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3117.8 - 7.91E+06 - - - 1.1008 - 1.326 0.139 - 176.7 1 2 0 0.001 8 0 0 0 3.44E+08 3.76E+08 - - - 0.9183 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.14833.14833.2 0.000936 16-Sep K.GFVTADMIR.E sp|Q9UHQ9|NB5R1_HUMAN 1 1008.5063 1.15 57400 14833 2 1008.507601 505.2604 NADH-cytochrome b5 reductase 1 OS=Homo sapiens OX=9606 GN=CYB5R1 PE=1 SV=1 5.84 3117.9 - 457628 - - - 1.3386 - 1.899 0.426 - 235.7 1 2 0 0.0014 9 0 0 0 2.08E+07 1.80E+07 - - - 4.0424 0.9736 230117_WJC_METTL3_WT_vs_EV_F07.14834.14834.2 3.34 12-Jun K.IGIEIIK[136.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 792.52 2.3 57401 14834 2 792.520237 397.2673 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3118 - 1.34E+06 - - - 0.2473 - 1.407 0 - 57.5 2 2 0 0.0002 7 0 0 0 2.66E+10 1.15E+10 - - - -0.0116 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.14836.14836.2 0.0906 12-Aug R.FC[160.03]DVLLR.V "sp|Q9HBE1|PATZ1_HUMAN,tr|B1ARF3|B1ARF3_HUMAN" 2 921.4742 0.03 57403 14836 2 921.473861 461.7444 "POZ-, AT hook-, and zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=PATZ1 PE=1 SV=1" 5.83 3118.1 - 1.02E+06 - - - -0.3928 - 1.592 0.323 - 230 1 2 0 -0.0004 7 0 0 0 2.96E+07 1.10E+09 - - - 2.8999 0.8975 230117_WJC_METTL3_WT_vs_EV_F07.14837.14837.2 2.83 14-Mar R.KPC[160.03]SDDYR.K "sp|Q2TAA8|TXIP1_HUMAN,tr|B4DXD0|B4DXD0_HUMAN,tr|H3BQ72|H3BQ72_HUMAN,tr|H3BNS9|H3BNS9_HUMAN" 4 1039.4393 96.01 57404 14837 2 1039.440293 520.7269 Translin-associated factor X-interacting protein 1 OS=Homo sapiens OX=9606 GN=TSNAXIP1 PE=1 SV=1 5.95 3118.3 - 256916 - - - 0.9611 - 0.945 0.1 - 22.7 30 2 0 0.001 8 0 0 0 7.02E+06 7.31E+04 - - - -1.0512 0.9887 230117_WJC_METTL3_WT_vs_EV_F07.14841.14841.2 0.342 12-Jun K.LFQPFGK.V sp|Q14966|ZN638_HUMAN 1 835.4592 1.31 57406 14841 2 835.459515 418.7369 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 8.75 3118.8 - 833686 - - - 0.3471 - 1.194 0.127 - 82.8 1 2 0 0.0003 7 0 0 0 8.03E+07 6.14E+07 - - - 0.5407 0.998 230117_WJC_METTL3_WT_vs_EV_F07.14846.14846.2 0.0629 16-Aug K.IPFASLASR.L sp|P35573|GDE_HUMAN 1 960.5393 0.87 57409 14846 2 960.5422 481.2769 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3119.4 - 825914 - - - 3.0545 - 1.542 0.277 - 159.9 1 2 0 0.0029 9 0 0 0 4.74E+07 5.44E+07 - - - 2.3389 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.14848.14848.2 0.00673 18-Aug R.VLLGEGVLTK[136.11].E "sp|Q96S99|PKHF1_HUMAN,sp|Q9H8W4|PKHF2_HUMAN,tr|K7ELB8|K7ELB8_HUMAN,tr|K7EIX0|K7EIX0_HUMAN" 4 1035.6419 0.79 57411 14848 2 1035.642552 518.8282 Pleckstrin homology domain-containing family F member 1 OS=Homo sapiens OX=9606 GN=PLEKHF1 PE=1 SV=3 5.97 3119.6 - 2.55E+06 - - - 0.5842 - 1.846 0.434 - 159.5 1 2 0 0.0006 10 0 0 0 5.20E+07 6.58E+07 - - - 3.9575 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.14857.14857.2 7.48E-05 12-Aug K.FDLMYAK[136.11].R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 894.4401 3.23 57416 14857 2 894.440563 448.2273 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3120.7 - 1.15E+07 - - - 0.5445 - 1.763 0.279 - 196.1 1 2 0 0.0005 7 0 0 0 1.36E+09 4.21E+08 - - - 2.8982 0.9942 230117_WJC_METTL3_WT_vs_EV_F07.14869.14869.2 0.433 14-Jul R.LYELDGLR.E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 977.5182 2.95 57423 14869 2 977.517344 489.7664 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3122.1 - 822374 - - - -0.8716 - 1.357 0.22 - 173 1 2 0 -0.0009 8 0 0 0 9.55E+08 3.23E+08 - - - 1.5864 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.14875.14875.2 0.215 14-Aug R.LYELDGLR[166.11].E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 987.5265 2.95 57428 14875 2 987.528487 494.7705 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3122.6 - 678274 - - - 2.0465 - 1.688 0.262 - 192 2 2 0 0.002 8 0 0 0 9.55E+08 3.23E+08 - - - 2.42 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.14881.14881.2 0.0131 16-Sep K.IPFASLASR[166.11].L sp|P35573|GDE_HUMAN 1 970.5475 1.65 57432 14881 2 970.547808 486.281 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3123.3 - 839966 - - - 0.2803 - 1.636 0.318 - 210.4 1 2 0 0.0003 9 0 0 0 4.57E+07 2.77E+07 - - - 2.8138 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.14882.14882.2 0.0218 14-Sep R.VPTWGPLR[166.11].G "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 3 934.5264 1.19 57433 14882 2 934.526553 468.2705 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.72 3123.4 - 3.50E+06 - - - 0.1562 - 1.786 0.38 - 310.4 1 2 0 0.0001 8 0 0 0 2.10E+08 1.77E+08 - - - 3.5968 0.8493 230117_WJC_METTL3_WT_vs_EV_F07.14889.14889.2 2.42 12-Jun R.FLSEMLK.S sp|P15924|DESP_HUMAN 1 866.4572 8.73 57435 14889 2 866.456194 434.2359 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 3124.3 - 4.23E+06 - - - -1.1334 - 1.116 0.02 - 90.8 3 2 0 -0.001 7 0 0 0 1.71E+08 1.96E+07 - - - -0.677 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.14901.14901.2 0.115 12-Jul R.IVFQEFR[166.11].Q "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN" 2 947.5104 0.85 57443 14901 2 947.510016 474.7625 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3125.9 - 4.74E+06 - - - -0.4285 - 1.448 0.235 - 206.1 1 2 0 -0.0004 7 0 0 0 3.45E+08 4.07E+08 - - - 1.9495 1 230117_WJC_METTL3_WT_vs_EV_F07.14918.14918.2 1.49E-07 13/22 K.FAQALGLTEAVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1254.7063 0.72 57448 14918 2 1254.703846 628.3604 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3128.4 - 483335 - - - -1.9861 - 2.585 0.481 - 623.2 1 2 0 -0.0025 12 0 0 0 2.52E+07 3.52E+07 - - - 5.0918 0.9886 230117_WJC_METTL3_WT_vs_EV_F07.14924.14924.2 0.807 12-Aug K.FLSVLER[166.11].Q sp|P07099|HYEP_HUMAN 1 872.4995 0.97 57450 14924 2 872.498949 437.257 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 6 3129.2 - 1.21E+06 - - - -0.6579 - 1.41 0.109 - 208.7 1 2 0 -0.0006 7 0 0 0 1.25E+08 1.29E+08 - - - 0.9346 0.8525 230117_WJC_METTL3_WT_vs_EV_F07.14925.14925.2 0.025 16-Jul Y.FLPVEETLK.K "sp|Q8N7H5|PAF1_HUMAN,tr|B4DGJ5|B4DGJ5_HUMAN" 2 1074.5961 7.4 57451 14925 2 1074.595696 538.3053 RNA polymerase II-associated factor 1 homolog OS=Homo sapiens OX=9606 GN=PAF1 PE=1 SV=2 4.53 3129.4 - 797644 - - - -0.3871 - 1.425 0.291 - 170.2 1 1 0 -0.0004 9 0 0 0 2.46E+07 3.33E+06 - - - 2.2148 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.14930.14930.2 0.00863 13/22 K.FAQALGLTEAVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1246.6921 0.72 57453 14930 2 1246.688725 624.3533 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3130 - 635094 - - - -2.7376 - 2.431 0.411 - 530.8 1 2 0 -0.0034 12 0 0 0 2.52E+07 3.52E+07 - - - 4.4128 0.8903 230117_WJC_METTL3_WT_vs_EV_F07.14931.14931.2 4.92 12-Jun K.LGFEEFK.Y "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 868.4331 2.34 57454 14931 2 868.432124 435.2238 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 3130.1 - 3.68E+06 - - - -1.0893 - 0.987 0.072 - 88.4 1 2 0 -0.0009 7 0 0 0 3.64E+08 1.56E+08 - - - -0.469 0.9951 230117_WJC_METTL3_WT_vs_EV_F07.14932.14932.2 0.281 18-Oct R.INEILSNALK.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 3 1113.6394 3.52 57455 14932 2 1113.637935 557.827 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3130.2 - 1.08E+06 - - - -1.2922 - 1.677 0.202 - 242.2 1 2 0 -0.0014 10 0 0 0 1.81E+07 5.14E+06 - - - 1.9756 0.9827 230117_WJC_METTL3_WT_vs_EV_F07.14941.14941.2 0.00692 14-Aug R.DAFVYAIK.N "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 925.4909 0.94 57456 14941 2 925.486992 463.7527 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 5.83 3131.7 - 3.53E+06 - - - -4.2432 - 1.556 0.298 - 268.5 1 2 0 -0.0039 8 0 0 0 2.48E+08 2.65E+08 - - - 2.5742 0.9961 230117_WJC_METTL3_WT_vs_EV_F07.14954.14954.2 0.913 16-Sep R.AFSYYGPLR[166.11].T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1082.5425 0.9 57463 14954 2 1082.539316 542.2785 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3133.3 - 2.93E+06 - - - -2.896 - 1.956 0.335 - 331.8 1 2 0 -0.0031 9 0 0 0 4.67E+08 5.17E+08 - - - 3.4553 1 230117_WJC_METTL3_WT_vs_EV_F07.14959.14959.2 4.73E-05 16-Sep R.AFSYYGPLR.T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1072.5342 0.9 57465 14959 2 1072.533914 537.2744 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3134 - 1.86E+06 - - - -0.2489 - 1.878 0.521 - 292.7 1 2 0 -0.0003 9 0 0 0 4.67E+08 5.17E+08 - - - 4.7122 0.9955 230117_WJC_METTL3_WT_vs_EV_F07.14962.14962.2 0.934 16-Sep K.LFVQDLATR[166.11].V sp|P33176|KINH_HUMAN 1 1071.5952 0.99 57467 14962 2 1071.595421 536.8049 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 5.84 3134.3 - 1.85E+06 - - - 0.1922 - 1.361 0.183 - 225.8 1 2 0 0.0002 9 0 0 0 3.16E+07 3.19E+07 - - - 1.2843 0.9897 230117_WJC_METTL3_WT_vs_EV_F07.14963.14963.2 0.00667 14-Jun K.LLFYATSR.A "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 969.5284 0.37 57468 14963 2 969.525242 485.7715 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 8.75 3134.4 - 1.44E+06 - - - -3.2232 - 1.393 0.327 - 122.8 1 2 0 -0.0031 8 0 0 0 7.51E+07 2.02E+08 - - - 2.4549 0.9863 230117_WJC_METTL3_WT_vs_EV_F07.14966.14966.2 0.0817 12-Jun K.YLPDIIK.D sp|O15355|PPM1G_HUMAN 1 860.5008 3.58 57470 14966 2 860.499113 431.2577 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 5.83 3134.8 - 6.74E+06 - - - -1.9082 - 1.214 0.239 - 102.9 1 2 0 -0.0016 7 0 0 0 2.91E+08 8.12E+07 - - - 1.4202 0.9949 230117_WJC_METTL3_WT_vs_EV_F07.14977.14977.2 0.128 16-Sep R.ILDSAEFIK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1042.579 0.94 57475 14977 2 1042.576798 522.2968 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3136.1 - 1.15E+06 - - - -2.1236 - 1.691 0.258 - 161.6 1 2 0 -0.0022 9 0 0 0 1.33E+10 1.41E+10 - - - 2.4657 0.9721 230117_WJC_METTL3_WT_vs_EV_F07.14980.14980.2 0.0638 12-Jul K.YNIMLVR.L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 907.495 8.6 57476 14980 2 907.4906 454.7548 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3136.5 - 3.87E+06 - - - -4.8022 - 1.523 0.278 - 211 1 2 0 -0.0044 7 0 0 0 3.06E+09 3.56E+08 - - - 2.4259 0.9125 230117_WJC_METTL3_WT_vs_EV_F07.14983.14983.2 4.8 12-May R.IFLQDIK[136.11].K "sp|P02794|FRIH_HUMAN,tr|E9PRK8|E9PRK8_HUMAN,tr|E9PKY7|E9PKY7_HUMAN,tr|G3V1D1|G3V1D1_HUMAN,tr|E9PPQ4|E9PPQ4_HUMAN,tr|G3V192|G3V192_HUMAN" 6 883.5259 1.33 57479 14983 2 883.523752 442.7702 Ferritin heavy chain OS=Homo sapiens OX=9606 GN=FTH1 PE=1 SV=2 5.84 3136.9 - 1.18E+06 - - - -2.3791 - 1.134 0.124 - 65.1 2 2 0 -0.0021 7 0 0 0 1.08E+08 8.14E+07 - - - 0.2202 0.999 230117_WJC_METTL3_WT_vs_EV_F07.14998.14998.2 0.0705 16-Sep K.LFVQDLATR.V sp|P33176|KINH_HUMAN 1 1061.5869 0.99 57486 14998 2 1061.587714 531.8007 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 5.84 3138.9 - 1.62E+06 - - - 0.7244 - 1.714 0.253 - 306.5 1 2 0 0.0008 9 0 0 0 3.16E+07 3.19E+07 - - - 2.4683 0.9916 230117_WJC_METTL3_WT_vs_EV_F07.15010.15010.2 0.0138 20-Oct K.LVLLGESAVGK[136.11].S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1092.6634 1.28 57490 15010 2 1092.65906 547.339 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3140.5 - 1.47E+06 - - - -3.982 - 2.003 0.323 - 240.9 1 2 0 -0.0044 11 0 0 0 1.76E+08 1.38E+08 - - - 3.3045 0.9963 230117_WJC_METTL3_WT_vs_EV_F07.15020.15020.2 0.0598 12-Jul R.LNLYELK[136.11].E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 899.5208 1.96 57494 15020 2 899.520524 450.7677 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3141.8 - 1.89E+06 - - - -0.2724 - 1.577 0.157 - 148.2 1 2 0 -0.0002 7 0 0 0 3.46E+08 1.77E+08 - - - 1.6439 0.981 230117_WJC_METTL3_WT_vs_EV_F07.15024.15024.2 1.44 12-Aug R.LNLYELK.E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 891.5066 1.97 57496 15024 2 891.506062 446.7606 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3142.2 - 2.38E+06 - - - -0.5687 - 1.319 0.111 - 183.2 3 2 0 -0.0005 7 0 0 0 3.45E+08 1.76E+08 - - - 0.5248 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.15035.15035.2 0.0851 12-Jun K.YNIMLVR[166.11].L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 917.5032 8.6 57501 15035 2 917.502442 459.7589 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3143.6 - 8.20E+06 - - - -0.8567 - 1.508 0.289 - 153.1 1 2 0 -0.0008 7 0 0 0 3.05E+09 3.55E+08 - - - 2.4769 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.15037.15037.2 0.00244 16-Sep R.ILDSAEFIK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1034.5648 0.94 57502 15037 2 1034.56399 518.2897 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3143.8 - 1.51E+08 - - - -0.7945 - 1.793 0.474 - 162.2 1 2 0 -0.0008 9 0 0 0 1.32E+10 1.41E+10 - - - 4.2309 0.9918 230117_WJC_METTL3_WT_vs_EV_F07.15046.15046.2 0.0329 16-Aug K.YLPELMAEK.D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1092.5525 1.15 57508 15046 2 1092.550535 547.2835 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3144.8 - 3.47E+06 - - - -1.8287 - 1.251 0.307 - 167.4 2 2 0 -0.002 9 0 0 0 2.10E+08 1.82E+08 - - - 1.8213 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.15047.15047.2 0.0179 16-Aug K.YLPELMAEK[136.11].D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1100.5667 1.15 57509 15047 2 1100.5669 551.2906 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3144.9 - 2.54E+06 - - - 0.1517 - 1.284 0.298 - 196.3 1 2 0 0.0002 9 0 0 0 2.10E+08 1.82E+08 - - - 1.9652 0.996 230117_WJC_METTL3_WT_vs_EV_F07.15051.15051.2 0.0521 20-Sep K.LVLLGESAVGK.S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1084.6492 1.28 57510 15051 2 1084.647308 543.3319 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3145.5 - 6.33E+06 - - - -1.7545 - 1.957 0.221 - 231.1 1 2 0 -0.0019 11 0 0 0 1.76E+08 1.38E+08 - - - 2.489 0.9641 230117_WJC_METTL3_WT_vs_EV_F07.15055.15055.2 0.207 12-Jun R.AWYPLGR.L "sp|P46977|STT3A_HUMAN,sp|Q8TCJ2|STT3B_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 5 861.4497 1.65 57511 15055 2 861.448497 431.7321 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 8.79 3146.1 - 489619 - - - -1.4232 - 1.162 0.126 - 155.9 1 2 0 -0.0012 7 0 0 0 9.03E+07 5.48E+07 - - - 0.447 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.15061.15061.2 0.00861 12-Aug K.FADFMVK.D "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 14 856.4153 2.01 57512 15061 2 856.415011 429.2149 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 5.84 3147 - 2.70E+06 - - - -0.3503 - 1.582 0.376 - 186 1 2 0 -0.0003 7 0 0 0 7.76E+07 3.85E+07 - - - 3.2714 0.9943 230117_WJC_METTL3_WT_vs_EV_F07.15069.15069.2 0.908 14-Jul R.VMLYPSRI.- sp|P18077|RL35A_HUMAN 1 977.5368 0.81 57514 15069 2 977.537152 489.7757 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.72 3148.1 - 5.16E+06 - - - 0.3366 - 1.279 0.17 - 254.8 1 2 0 0.0003 8 0 0 0 1.52E+08 1.87E+08 - - - 1.0387 0.9842 230117_WJC_METTL3_WT_vs_EV_F07.15073.15073.2 0.00144 12-Jun K.FADFMVK[136.11].D "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 14 864.4295 2.01 57516 15073 2 864.42581 433.222 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 5.84 3148.6 - 1.13E+06 - - - -4.2814 - 1.319 0.378 - 72.3 1 2 0 -0.0037 7 0 0 0 7.76E+07 3.85E+07 - - - 2.709 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.15089.15089.2 0.0418 20-Dec R.MGAGMGFGLER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1134.519 2.34 57525 15089 2 1134.51968 568.2668 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 3150.6 - 1.36E+06 - - - 0.639 - 1.921 0.388 - 240.8 1 2 0 0.0007 11 0 0 0 8.03E+07 3.43E+07 - - - 3.6726 0.9966 230117_WJC_METTL3_WT_vs_EV_F07.15096.15096.2 0.0861 12-Aug K.WDPVVLK.N sp|Q9BVJ6|UT14A_HUMAN 1 855.4854 1.25 57530 15096 2 855.485099 428.75 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 5.84 3151.4 - 3.18E+06 - - - -0.3986 - 1.003 0.371 - 169.7 1 2 0 -0.0003 7 0 0 0 1.42E+08 1.14E+08 - - - 1.7906 0.9898 230117_WJC_METTL3_WT_vs_EV_F07.15101.15101.2 0.113 12-Aug R.EVAQMLK.S "sp|Q9HBL0|TENS1_HUMAN,tr|A0A804HI61|A0A804HI61_HUMAN,tr|E7EMG1|E7EMG1_HUMAN,tr|A0A2R8Y4T1|A0A2R8Y4T1_HUMAN,tr|A0A494C067|A0A494C067_HUMAN,tr|A0A087WWW7|A0A087WWW7_HUMAN,tr|C9J8K5|C9J8K5_HUMAN,tr|E9PGF5|E9PGF5_HUMAN,tr|C9JFT7|C9JFT7_HUMAN,tr|E9PF55|E9PF55_HUMAN,tr|E7ERH1|E7ERH1_HUMAN,tr|C9JI43|C9JI43_HUMAN" 12 817.4368 1.56 57533 15101 2 817.436084 409.7257 Tensin-1 OS=Homo sapiens OX=9606 GN=TNS1 PE=1 SV=2 6.1 3152 - 1.24E+06 - - - -0.8453 - 1.279 0.175 - 190.8 1 2 0 -0.0007 7 0 0 0 1.05E+08 6.71E+07 - - - 1.113 0.9276 230117_WJC_METTL3_WT_vs_EV_F07.15108.15108.2 0.0697 16-Sep H.VPIILVGNK[136.11].A "sp|O75628|REM1_HUMAN,sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,sp|Q8IXI1|MIRO2_HUMAN,sp|P55042|RAD_HUMAN,sp|Q9Y3L5|RAP2C_HUMAN,tr|I3L2C6|I3L2C6_HUMAN,tr|H3BST5|H3BST5_HUMAN,tr|A0A087X2C3|A0A087X2C3_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 16 959.6259 1.97 57538 15108 2 959.627301 480.8202 GTP-binding protein REM 1 OS=Homo sapiens OX=9606 GN=REM1 PE=1 SV=2 8.72 3152.7 - 463985 - - - 1.4568 - 1.743 0.238 - 179.2 1 1 0 0.0014 9 0 0 0 2.34E+07 1.19E+07 - - - 2.4058 0.999 230117_WJC_METTL3_WT_vs_EV_F07.15112.15112.2 0.114 14-Jun R.VMLYPSR[166.11]I.- sp|P18077|RL35A_HUMAN 1 987.5451 0.81 57541 15112 2 987.545953 494.7798 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.72 3153.1 - 2.50E+06 - - - 0.8708 - 1.4 0.317 - 156.9 1 2 0 0.0009 8 0 0 0 1.52E+08 1.87E+08 - - - 2.3969 0.9183 230117_WJC_METTL3_WT_vs_EV_F07.15121.15121.2 3.8 12-May R.DLGAYLR.Q "sp|Q9BRT2|UQCC2_HUMAN,tr|Q5TAQ0|Q5TAQ0_HUMAN,tr|V5IRT4|V5IRT4_HUMAN" 3 806.4287 0.16 57547 15121 2 806.428122 404.2216 Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1 5.84 3154.2 - 872765 - - - -0.6585 - 1.182 0.046 - 91.2 6 2 0 -0.0005 7 0 0 0 1.09E+07 6.93E+07 - - - -0.4372 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.15126.15126.2 0.00924 14-Aug K.LIYLVPEK.Q "sp|Q9NZM3|ITSN2_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN,tr|E7EPJ2|E7EPJ2_HUMAN" 3 973.5848 3.51 57550 15126 2 973.58597 487.7997 Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3 6 3154.8 - 1.47E+06 - - - 1.1822 - 1.5 0.348 - 186.5 1 2 0 0.0012 8 0 0 0 6.10E+07 1.74E+07 - - - 2.8338 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.15127.15127.2 0.00103 18-Nov R.ILALEADMTK.W "sp|Q4VCS5|AMOT_HUMAN,sp|Q9Y2J4|AMOL2_HUMAN,sp|Q8IY63|AMOL1_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 5 1103.5896 3.55 57551 15127 2 1103.59481 552.8021 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.37 3154.9 - 453896 - - - 4.6784 - 2.087 0.372 - 271.5 1 2 0 0.0052 10 0 0 0 2.58E+07 7.27E+06 - - - 3.8406 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.15132.15132.2 0.00642 14-Sep R.LLEIVSYK.L "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 963.5641 1.05 57554 15132 2 963.563795 482.7893 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6 3155.6 - 652865 - - - -0.2999 - 1.755 0.341 - 224 1 2 0 -0.0003 8 0 0 0 1.38E+08 1.32E+08 - - - 3.2559 1 230117_WJC_METTL3_WT_vs_EV_F07.15133.15133.2 3.10E-08 14/26 R.VPTANVSVVDLTC[160.03]R.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1529.7872 8.62 57555 15133 2 1529.791201 765.9009 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3155.8 - 290216 - - - 2.6298 - 2.765 0.6 - 520.1 1 2 0 0.004 14 0 0 0 7.76E+06 9.01E+05 - - - 6.0235 0.9659 230117_WJC_METTL3_WT_vs_EV_F07.15144.15144.2 3.26 12-May K.LVPGLFK[136.11].N "sp|P35226|BMI1_HUMAN,sp|P35227|PCGF2_HUMAN,tr|Q5T8Z6|Q5T8Z6_HUMAN,tr|A0A087X259|A0A087X259_HUMAN,tr|J3KT13|J3KT13_HUMAN,tr|R4GMX3|R4GMX3_HUMAN,tr|Q5T8Z4|Q5T8Z4_HUMAN" 7 780.4989 1.26 57561 15144 2 780.499473 391.2567 Polycomb complex protein BMI-1 OS=Homo sapiens OX=9606 GN=BMI1 PE=1 SV=2 8.75 3157.1 - 2.80E+06 - - - 0.7201 - 0.903 0.152 - 87.4 2 2 0 0.0006 7 0 0 0 1.20E+08 9.47E+07 - - - -0.2943 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.15145.15145.2 0.168 14-Sep R.VGEIVVFR[166.11].L "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 927.5417 1.99 57562 15145 2 927.543295 464.7781 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.97 3157.2 - 3.02E+06 - - - 1.6959 - 1.658 0.318 - 300.4 1 2 0 0.0016 8 0 0 0 1.11E+08 5.59E+07 - - - 2.9142 0.9916 230117_WJC_METTL3_WT_vs_EV_F07.15148.15148.2 3.41 14-Jul K.GAIEVLIR.E "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 869.5335 1.08 57565 15148 2 869.534859 435.774 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 6 3157.5 - 855518 - - - 1.6181 - 1.393 0.077 - 113.8 1 2 0 0.0014 8 0 0 0 6.05E+07 5.58E+07 - - - 0.6089 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.15153.15153.2 0.00185 16-Oct K.ANPALYVLR[166.11].E sp|Q6P2Q9|PRP8_HUMAN 1 1025.5897 1.36 57568 15153 2 1025.590422 513.8021 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.79 3158.1 - 1.83E+06 - - - 0.6699 - 1.559 0.386 - 337.2 1 2 0 0.0007 9 0 0 0 1.66E+08 1.22E+08 - - - 3.1764 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.15177.15177.2 0.619 14-Sep K.GAIEVLIR[166.11].E "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 879.5417 1.09 57582 15177 2 879.542461 440.7781 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 6 3161.3 - 2.73E+06 - - - 0.8402 - 1.989 0.218 - 237 1 2 0 0.0007 8 0 0 0 6.05E+07 5.55E+07 - - - 2.7248 0.9931 230117_WJC_METTL3_WT_vs_EV_F07.15178.15178.2 1.94 12-Aug R.LIVDVIR.F "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 826.5276 1.21 57583 15178 2 826.528009 414.2711 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.84 3161.4 - 1.10E+06 - - - 0.4477 - 1.444 0.089 - 168.3 1 2 0 0.0004 7 0 0 0 1.20E+08 9.96E+07 - - - 0.8624 1 230117_WJC_METTL3_WT_vs_EV_F07.15182.15182.2 1.35E-07 13/28 R.NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1656.8459 5.16 57587 15182 2 1656.842962 829.4302 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3161.9 - 363206 - - - -1.7751 - 2.773 0.478 - 461.5 1 2 0 -0.0029 15 0 0 0 5.47E+07 1.06E+07 - - - 5.0781 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.15189.15189.2 0.00222 16-Sep K.ELGVGIALR.K sp|Q01469|FABP5_HUMAN 1 926.5549 10.47 57592 15189 2 926.554979 464.2847 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 6.1 3162.6 - 5.14E+06 - - - 0.068 - 1.695 0.238 - 334.7 1 2 0 0.0001 9 0 0 0 1.61E+08 1.53E+07 - - - 2.3255 0.994 230117_WJC_METTL3_WT_vs_EV_F07.15190.15190.2 0.241 12-Jun R.QMSLLLR[166.11].R sp|P25705|ATPA_HUMAN 1 869.5032 1.55 57593 15190 2 869.503366 435.7589 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 9.75 3162.6 - 3.50E+06 - - - 0.1587 - 1.404 0.129 - 138.1 1 2 0 0.0001 7 0 0 0 3.41E+08 2.19E+08 - - - 1.0689 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.15191.15191.2 0.00666 14-Jul K.FLVGFTNK[136.11].G "sp|P43307|SSRA_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|C9J5W0|C9J5W0_HUMAN" 6 932.5211 1.46 57594 15191 2 932.52164 467.2678 Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3 8.75 3162.7 - 3.07E+06 - - - 0.5759 - 1.603 0.429 - 130.5 1 2 0 0.0005 8 0 0 0 3.97E+08 2.73E+08 - - - 3.6326 0.9058 230117_WJC_METTL3_WT_vs_EV_F07.15192.15192.3 0.0489 Nov-44 R.YLYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1484.8126 0.14 57595 15192 3 1484.811797 495.9448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3162.8 - 708182 - - - -0.5725 - 1.599 0.324 - 99 1 2 1 -0.0008 12 0 0 0 1.17E+07 8.54E+07 - - - 3.4531 0.991 230117_WJC_METTL3_WT_vs_EV_F07.15193.15193.2 0.159 14-Jul R.EIGMWYAK[136.11].K sp|Q9H2U1|DHX36_HUMAN 1 1004.4881 0.99 57596 15193 2 1004.487384 503.2513 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 6.1 3162.9 - 2.17E+06 - - - -0.7019 - 1.421 0.141 - 146.4 1 2 0 -0.0007 8 0 0 0 1.51E+07 1.53E+07 - - - 1.1419 1 230117_WJC_METTL3_WT_vs_EV_F07.15194.15194.2 1.97E-06 16/28 R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 2.53 57597 15194 2 1646.836593 824.4261 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3163 - 319179 - - - -0.6315 - 2.771 0.485 - 701 1 2 0 -0.001 15 0 0 0 1.70E+07 6.71E+06 - - - 5.1287 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.15198.15198.2 0.307 12-Aug K.MDLLLTK[136.11].T "sp|Q6P3W7|SCYL2_HUMAN,tr|H0YIK6|H0YIK6_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 840.487 0.81 57599 15198 2 840.487574 421.2508 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.59 3163.4 - 4.77E+06 - - - 0.652 - 1.66 0.173 - 260.7 1 2 0 0.0005 7 0 0 0 1.08E+08 1.33E+08 - - - 1.9245 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.15199.15199.2 0.00368 16-Aug R.AFGYYGPLR[166.11].S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1052.5319 1.14 57600 15199 2 1052.53241 527.2732 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3163.5 - 3.30E+06 - - - 0.4978 - 1.364 0.423 - 280.7 1 2 0 0.0005 9 0 0 0 2.42E+09 2.11E+09 - - - 3.0632 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.15200.15200.2 0.000419 16-Aug R.AFGYYGPLR.S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1042.5236 1.03 57601 15200 2 1042.524818 522.2691 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3163.5 - 2.73E+06 - - - 1.153 - 1.28 0.38 - 223 1 2 0 0.0012 9 0 0 0 2.16E+09 2.10E+09 - - - 2.5615 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.15201.15201.2 0.112 16-Sep K.MLLYTEVTR[166.11].Y "sp|P31150|GDIA_HUMAN,sp|P50395|GDIB_HUMAN,tr|G5E9U5|G5E9U5_HUMAN,tr|Q5SX86|Q5SX86_HUMAN,tr|Q5SX90|Q5SX90_HUMAN,tr|V9GYF8|V9GYF8_HUMAN,tr|V9GYJ7|V9GYJ7_HUMAN" 7 1134.5983 1.26 57602 15201 2 1134.60005 568.3064 Rab GDP dissociation inhibitor alpha OS=Homo sapiens OX=9606 GN=GDI1 PE=1 SV=2 5.75 3163.7 - 775368 - - - 1.5856 - 1.485 0.214 - 209.4 1 2 0 0.0018 9 0 0 0 2.83E+07 2.25E+07 - - - 1.765 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.15204.15204.2 0.0844 14-Sep K.FLVGFTNK.G "sp|P43307|SSRA_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|C9J5W0|C9J5W0_HUMAN" 6 924.5069 1.45 57603 15204 2 924.50751 463.2607 Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3 8.75 3164.1 - 6.94E+06 - - - 0.6566 - 1.49 0.233 - 304.1 1 2 0 0.0006 8 0 0 0 3.95E+08 2.72E+08 - - - 1.9644 0.9947 230117_WJC_METTL3_WT_vs_EV_F07.15206.15206.2 0.712 12-Aug K.LYGFPYK[136.11].L "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 894.4731 0.62 57605 15206 2 894.475246 448.2438 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 8.5 3164.2 - 1.22E+06 - - - 2.4104 - 1.313 0.167 - 185.9 1 2 0 0.0022 7 0 0 0 4.99E+07 8.06E+07 - - - 1.1366 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.15228.15228.2 0.0016 14-Aug K.AFAMIIDK.L "sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BND9|H3BND9_HUMAN" 8 907.4837 2.58 57620 15228 2 907.484971 454.7491 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 5.88 3167 - 4.00E+06 - - - 1.373 - 1.735 0.396 - 211.7 1 2 0 0.0012 8 0 0 0 1.60E+08 6.21E+07 - - - 3.6273 0.9957 230117_WJC_METTL3_WT_vs_EV_F07.15230.15230.2 0.0195 12-Jul K.LYGFPYK.L "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 886.4589 0.56 57621 15230 2 886.460116 444.2367 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 8.5 3167.2 - 1.60E+06 - - - 1.383 - 1.176 0.208 - 165.2 1 2 0 0.0012 7 0 0 0 5.17E+07 9.17E+07 - - - 1.0906 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.15234.15234.2 0.0543 16-Aug R.LLGYVATLK[136.11].D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 984.6099 2.6 57623 15234 2 984.612499 493.3122 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 8.59 3167.6 - 2.49E+06 - - - 2.6213 - 1.534 0.304 - 120.2 1 2 0 0.0026 9 0 0 0 4.66E+08 1.79E+08 - - - 2.5234 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.15238.15238.2 0.0143 20-Dec R.VFSGLVSTGLK.V sp|P13639|EF2_HUMAN 1 1106.6336 4.49 57626 15238 2 1106.635794 554.3241 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.72 3168.1 - 919341 - - - 2.0187 - 2.151 0.462 - 408.2 1 2 0 0.0022 11 0 0 0 1.73E+08 3.85E+07 - - - 4.5247 1 230117_WJC_METTL3_WT_vs_EV_F07.15246.15246.2 1.29E-05 16-Nov K.YMAC[160.03]C[160.03]LLYR.G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1248.5454 3.16 57632 15246 2 1248.546692 625.28 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3168.8 - 756816 - - - 1.07 - 1.816 0.594 - 509.8 1 2 0 0.0013 9 0 0 0 4.09E+08 1.29E+08 - - - 5.154 0.9963 230117_WJC_METTL3_WT_vs_EV_F07.15253.15253.2 0.186 12-Jul R.FAVFIEK.V sp|Q16352|AINX_HUMAN 1 852.4745 0.88 57637 15253 2 852.473706 427.2445 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 6 3169.5 - 3.56E+06 - - - -0.9795 - 1.638 0.198 - 150.3 1 2 0 -0.0008 7 0 0 0 1.64E+08 1.87E+08 - - - 2.0668 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.15254.15254.2 3.83E-05 20-Sep R.VFSGLVSTGLK[136.11].V sp|P13639|EF2_HUMAN 1 1114.6478 4.45 57638 15254 2 1114.650444 558.3312 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.72 3169.6 - 652567 - - - 2.4079 - 1.823 0.463 - 194.1 1 2 0 0.0027 11 0 0 0 1.71E+08 3.85E+07 - - - 4.0843 1 230117_WJC_METTL3_WT_vs_EV_F07.15255.15255.2 2.47E-08 16-Oct K.YMAC[160.03]C[160.03]LLYR[166.11].G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1258.5536 3.16 57639 15255 2 1258.553066 630.2841 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3169.7 - 547194 - - - -0.445 - 1.9 0.608 - 390.6 1 2 0 -0.0006 9 0 0 0 4.09E+08 1.29E+08 - - - 5.3884 0.9893 230117_WJC_METTL3_WT_vs_EV_F07.15263.15263.2 0.474 12-Jun K.NLILVVR[166.11].G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 835.5519 1.2 57643 15263 2 835.552876 418.7832 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3170.7 - 8.61E+06 - - - 1.1765 - 1.282 0.081 - 198.3 1 2 0 0.001 7 0 0 0 2.56E+08 2.12E+08 - - - 0.4261 0.9838 230117_WJC_METTL3_WT_vs_EV_F07.15269.15269.2 1.44 12-Jul K.NLILVVR.G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 825.5436 1.2 57647 15269 2 825.543392 413.7791 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3171.4 - 8.16E+06 - - - -0.2798 - 1.328 0.078 - 208.9 1 2 0 -0.0002 7 0 0 0 2.56E+08 2.12E+08 - - - 0.5159 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.15270.15270.2 0.00895 12-Jun K.EILFYDR.L sp|Q08J23|NSUN2_HUMAN 1 954.4811 1.85 57648 15270 2 954.481362 478.2478 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.37 3171.4 - 2.86E+06 - - - 0.2934 - 1.344 0.376 - 176.7 1 2 0 0.0003 7 0 0 0 2.18E+08 1.18E+08 - - - 2.7548 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.15274.15274.2 0.0205 20-Dec R.IALTDNALIAR[166.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1179.6851 0.84 57650 15274 2 1179.683825 590.8498 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3171.9 - 825260 - - - -1.074 - 2.251 0.295 - 406 1 2 0 -0.0013 11 0 0 0 2.81E+07 3.34E+07 - - - 3.4144 0.9935 230117_WJC_METTL3_WT_vs_EV_F07.15275.15275.2 0.00566 18-Oct K.ILVYSLEAGR[166.11].R "sp|Q8N3Y1|FBXW8_HUMAN,tr|A0A499FIY5|A0A499FIY5_HUMAN" 2 1129.6371 1.91 57651 15275 2 1129.633223 565.8258 F-box\WD repeat-containing protein 8 OS=Homo sapiens OX=9606 GN=FBXW8 PE=1 SV=2 6 3172 - 301294 - - - -3.4135 - 1.927 0.31 - 248.6 1 2 0 -0.0039 10 0 0 0 1.04E+07 5.43E+06 - - - 3.1604 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.15280.15280.2 0.115 16-Aug R.LLLPTPTVK.Q "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 980.627 2.4 57654 15280 2 980.627364 491.3208 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 3172.5 - 7.10E+06 - - - 0.3528 - 1.439 0.276 - 207.9 1 2 0 0.0003 9 0 0 0 7.43E+08 3.10E+08 - - - 2.1323 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.15286.15286.2 0.212 14-Jul K.LIINSLYK[136.11].N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 970.5943 0.97 57658 15286 2 970.594529 486.3044 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3173.1 - 2.06E+06 - - - 0.2689 - 1.302 0.296 - 108.7 1 2 0 0.0003 8 0 0 0 3.18E+08 3.29E+08 - - - 2.0231 0.995 230117_WJC_METTL3_WT_vs_EV_F07.15287.15287.2 0.354 14-Aug K.GLVFLNGK.L sp|L0R8F8|MIDUO_HUMAN 1 846.4963 1.84 57659 15287 2 846.49552 424.2554 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 8.75 3173.2 - 1.45E+06 - - - -0.9675 - 1.629 0.171 - 241.6 1 2 0 -0.0008 8 0 0 0 1.63E+08 8.83E+07 - - - 1.7754 0.967 230117_WJC_METTL3_WT_vs_EV_F07.15290.15290.2 4.55 12-May R.FLTVMMK.H "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 868.4551 1.29 57660 15290 2 868.454973 435.2348 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.75 3173.6 - 1.36E+06 - - - -0.1082 - 1.01 0.12 - 89 1 2 0 -0.0001 7 0 0 0 4.54E+08 3.51E+08 - - - -0.0412 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.15297.15297.2 0.00197 18-Sep K.ILVYSLEAGR.R "sp|Q8N3Y1|FBXW8_HUMAN,tr|A0A499FIY5|A0A499FIY5_HUMAN" 2 1119.6288 1.91 57664 15297 2 1119.629162 560.8217 F-box\WD repeat-containing protein 8 OS=Homo sapiens OX=9606 GN=FBXW8 PE=1 SV=2 6 3174.3 - 838830 - - - 0.3153 - 1.795 0.359 - 165.9 1 2 0 0.0004 10 0 0 0 1.04E+07 5.43E+06 - - - 3.3254 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.15298.15298.2 0.00124 20-Nov R.IALTDNALIAR.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1169.6768 0.84 57665 15298 2 1169.677068 585.8457 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3174.5 - 873889 - - - 0.2103 - 2.335 0.409 - 346.4 1 2 0 0.0002 11 0 0 0 2.81E+07 3.34E+07 - - - 4.3559 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.15301.15301.2 0.00893 14-Jul K.LIINSLYK.N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 962.5801 0.97 57666 15301 2 962.579838 482.2973 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3174.9 - 5.28E+06 - - - -0.2389 - 1.471 0.305 - 99 1 2 0 -0.0002 8 0 0 0 3.18E+08 3.29E+08 - - - 2.4576 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.15314.15314.2 0.0534 14-Sep K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 2.54 57672 15314 2 843.506625 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 3176.4 - 4.24E+06 - - - 0.0664 - 2.059 0.304 - 228.5 1 2 0 0.0001 8 0 0 0 2.34E+08 9.19E+07 - - - 3.4645 0.9965 230117_WJC_METTL3_WT_vs_EV_F07.15318.15318.2 0.204 16-Aug R.LPEAAFLAR.T "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 986.5549 2.67 57674 15318 2 986.554755 494.2847 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 6 3176.8 - 4.87E+06 - - - -0.1632 - 1.467 0.203 - 195.5 1 2 0 -0.0002 9 0 0 0 3.90E+08 1.46E+08 - - - 1.649 0.9628 230117_WJC_METTL3_WT_vs_EV_F07.15337.15337.2 2.32 12-May K.LVFDGLR[166.11].K sp|P15924|DESP_HUMAN 1 828.4733 42.88 57684 15337 2 828.473295 415.2439 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.84 3179.1 - 1.54E+06 - - - -0.0157 - 1.091 0.09 - 92.7 2 2 0 0 7 0 0 0 3.29E+09 7.68E+07 - - - -0.1528 0.9939 230117_WJC_METTL3_WT_vs_EV_F07.15343.15343.2 0.00139 18-Sep R.LVQAFQFTDK[136.11].H "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 3 1203.6379 3.58 57686 15343 2 1203.633661 602.8262 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.84 3179.9 - 375278 - - - -3.5418 - 1.797 0.365 - 179.8 1 2 0 -0.0043 10 0 0 0 1.37E+07 3.84E+06 - - - 3.3716 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.15349.15349.2 0.00484 16-Oct R.LPEAAFLAR[166.11].T "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 996.5632 2.69 57687 15349 2 996.562225 499.2889 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 6 3180.8 - 3.61E+06 - - - -0.9643 - 1.787 0.327 - 382 1 2 0 -0.001 9 0 0 0 3.89E+08 1.45E+08 - - - 3.1354 0.9819 230117_WJC_METTL3_WT_vs_EV_F07.15366.15366.2 0.284 14-Aug R.SVLLEAIR.K sp|Q92558|WASF1_HUMAN 1 899.544 1.75 57696 15366 2 899.545084 450.7793 Wiskott-Aldrich syndrome protein family member 1 OS=Homo sapiens OX=9606 GN=WASF1 PE=1 SV=1 5.72 3183 - 655724 - - - 1.1862 - 1.471 0 - 159.8 2 2 0 0.0011 8 0 0 0 2.48E+07 1.42E+07 - - - 0.0702 0.9935 230117_WJC_METTL3_WT_vs_EV_F07.15368.15368.2 4.12 12-Aug R.IYLYLTK[136.11].V "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 920.5463 1.91 57697 15368 2 920.548623 461.2804 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.5 3183.2 - 678199 - - - 2.5724 - 1.447 0.113 - 180.8 1 2 0 0.0024 7 0 0 0 7.58E+07 3.96E+07 - - - 1.0456 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.15370.15370.2 0.0012 16-Aug R.ALDPLLYEK.E "sp|Q92696|PGTA_HUMAN,tr|H0YMG5|H0YMG5_HUMAN,tr|H0YKZ8|H0YKZ8_HUMAN,tr|H0YLH3|H0YLH3_HUMAN,tr|H0YLG7|H0YLG7_HUMAN" 5 1060.5805 0.12 57699 15370 2 1060.578326 531.2975 Geranylgeranyl transferase type-2 subunit alpha OS=Homo sapiens OX=9606 GN=RABGGTA PE=1 SV=2 4.37 3183.4 - 1.20E+06 - - - -2.014 - 1.841 0.309 - 183.3 1 2 0 -0.0021 9 0 0 0 2.68E+07 2.23E+08 - - - 3.0883 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.15377.15377.2 0.0456 22-Jul K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.17 57704 15377 2 1277.750926 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3184.3 - 191529 - - - 1.0432 - 1.569 0.137 - 78 1 2 0 0.0013 12 0 0 0 9.60E+07 8.20E+07 - - - 1.2376 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.15381.15381.2 0.288 18-Oct K.IVLLSANSIR.A "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 1084.6604 2.27 57706 15381 2 1084.660105 543.3375 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 9.75 3184.8 - 2.04E+06 - - - -0.3125 - 1.808 0.273 - 296 1 2 0 -0.0003 10 0 0 0 4.06E+07 1.79E+07 - - - 2.7103 0.9933 230117_WJC_METTL3_WT_vs_EV_F07.15383.15383.2 0.0804 18-Jul R.LVQAFQFTDK.H "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 3 1195.6237 3.58 57708 15383 2 1195.624335 598.8191 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.84 3185 - 465261 - - - 0.511 - 1.314 0.163 - 48.7 2 2 0 0.0006 10 0 0 0 1.37E+07 3.84E+06 - - - 0.8725 0.9958 230117_WJC_METTL3_WT_vs_EV_F07.15388.15388.2 0.996 12-Aug R.IYLYLTK.V "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 912.5321 1.71 57711 15388 2 912.533042 457.2733 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.5 3185.7 - 2.22E+06 - - - 1.0816 - 1.585 0.083 - 219.5 1 2 0 0.001 7 0 0 0 7.65E+07 4.47E+07 - - - 1.1131 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.15390.15390.2 2.23E-05 14-Sep R.NIVLYDMR.Q "sp|Q9NV06|DCA13_HUMAN,tr|A0A087WT20|A0A087WT20_HUMAN,tr|A0A087X1F8|A0A087X1F8_HUMAN" 3 1022.5219 999 57713 15390 2 1022.523217 512.2682 DDB1- and CUL4-associated factor 13 OS=Homo sapiens OX=9606 GN=DCAF13 PE=1 SV=2 5.84 3185.9 - 552194 - - - 1.287 - 1.688 0.471 - 295.8 1 2 0 0.0013 8 0 0 0 1.57E+07 0.00E+00 - - - 4.0984 0.9894 230117_WJC_METTL3_WT_vs_EV_F07.15391.15391.2 0.0334 16-May R.YLYLSTMER.S "sp|Q10570|CPSF1_HUMAN,tr|A0A087X101|A0A087X101_HUMAN" 2 1174.5692 0.63 57714 15391 2 1174.574331 588.2919 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6 3186.1 - 298185 - - - 4.3292 - 1.242 0.256 - 66.8 1 2 0 0.0051 9 0 0 0 4.06E+06 6.46E+06 - - - 1.5572 0.99 230117_WJC_METTL3_WT_vs_EV_F07.15395.15395.2 0.158 12-Aug R.WGGLDLR[166.11].R sp|Q9H7N4|SFR19_HUMAN 1 825.4373 0.89 57716 15395 2 825.437314 413.7259 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.84 3186.6 - 2.45E+06 - - - 0.0691 - 1.316 0.11 - 246.2 1 2 0 0.0001 7 0 0 0 8.13E+07 9.09E+07 - - - 0.7235 0.989 230117_WJC_METTL3_WT_vs_EV_F07.15396.15396.2 1.54 12-Jul K.FLLLQQK[136.11].Y "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 896.5575 2.05 57717 15396 2 896.560181 449.286 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 8.75 3186.7 - 827575 - - - 3.0026 - 1.273 0.14 - 143.3 1 2 0 0.0027 7 0 0 0 1.07E+08 5.24E+07 - - - 0.839 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.15397.15397.2 8.50E-07 14/22 K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 58.64 57718 15397 2 1356.689402 679.3515 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3186.9 - 670626 - - - 0.6582 - 2.782 0.357 - 894.8 1 2 0 0.0009 12 0 0 0 2.18E+07 3.72E+05 - - - 4.3697 0.9931 230117_WJC_METTL3_WT_vs_EV_F07.15399.15399.2 0.0202 12-Aug R.WFVTC[160.03]VR.Q "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN,tr|A0A140T954|A0A140T954_HUMAN" 3 966.4746 0.62 57720 15399 2 966.478746 484.2446 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 8.25 3187.1 - 537712 - - - 4.3333 - 1.302 0.28 - 195.1 1 2 0 0.0042 7 0 0 0 1.25E+07 2.01E+07 - - - 1.944 0.9877 230117_WJC_METTL3_WT_vs_EV_F07.15402.15402.2 0.15 22-Aug K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.18 57723 15402 2 1287.761496 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3187.5 - 393161 - - - 2.8212 - 1.34 0.117 - 104.6 1 2 0 0.0036 12 0 0 0 9.83E+07 8.29E+07 - - - 0.6741 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.15403.15403.2 0.0528 16-Jul R.YLYLSTMER[166.11].S "sp|Q10570|CPSF1_HUMAN,tr|A0A087X101|A0A087X101_HUMAN" 2 1184.5775 0.62 57724 15403 2 1184.576905 593.296 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6 3187.6 - 307890 - - - -0.5158 - 1.328 0.358 - 177.1 1 2 0 -0.0006 9 0 0 0 4.06E+06 6.53E+06 - - - 2.5057 1 230117_WJC_METTL3_WT_vs_EV_F07.15407.15407.2 0.000436 16-Dec R.PAVLSGYFK.Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 980.5331 1.07 57726 15407 2 980.535113 491.2738 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.01 3188.2 - 3.77E+06 - - - 2.0346 - 2.241 0.44 - 564.9 1 1 0 0.002 9 0 0 0 2.71E+08 2.54E+08 - - - 4.6247 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.15408.15408.2 0.0858 14-Aug R.LLLNYAVR.L "sp|Q92989|CLP1_HUMAN,tr|E9PL17|E9PL17_HUMAN,tr|E9PKV5|E9PKV5_HUMAN" 3 960.5757 4.08 57727 15408 2 960.577696 481.2951 Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1 8.75 3188.3 - 763972 - - - 2.1279 - 1.608 0.219 - 196 1 2 0 0.002 8 0 0 0 2.59E+07 6.34E+06 - - - 2.0904 0.9958 230117_WJC_METTL3_WT_vs_EV_F07.15409.15409.2 0.598 12-Jul R.WGGLDLR.R sp|Q9H7N4|SFR19_HUMAN 1 815.429 0.91 57728 15409 2 815.430334 408.7218 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.84 3188.3 - 2.23E+06 - - - 1.6519 - 1.295 0.172 - 234.9 1 2 0 0.0013 7 0 0 0 8.28E+07 9.09E+07 - - - 1.1301 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.15415.15415.2 0.103 14-Aug K.LGFESIYK.L "sp|P49643|PRI2_HUMAN,tr|A0A5F9ZHU7|A0A5F9ZHU7_HUMAN" 2 955.5015 1.91 57732 15415 2 955.503822 478.758 DNA primase large subunit OS=Homo sapiens OX=9606 GN=PRIM2 PE=1 SV=2 6 3189.1 - 1.44E+06 - - - 2.4469 - 1.502 0.202 - 152.2 1 2 0 0.0023 8 0 0 0 3.18E+07 1.67E+07 - - - 1.7591 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.15418.15418.2 6.05E-05 18-Sep R.LITLEEEMTK.Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1205.6213 2.53 57735 15418 2 1205.626919 603.8179 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3189.3 - 474187 - - - 4.6267 - 1.71 0.473 - 192.6 1 2 0 0.0056 10 0 0 0 3.52E+07 1.39E+07 - - - 4.0303 1 230117_WJC_METTL3_WT_vs_EV_F07.15421.15421.2 0.000289 16-Oct R.PAVLSGYFK[136.11].Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 988.5473 1.06 57736 15421 2 988.549676 495.2809 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.01 3189.7 - 3.40E+06 - - - 2.3853 - 2.302 0.448 - 376.8 1 1 0 0.0024 9 0 0 0 2.72E+08 2.56E+08 - - - 4.7614 0.998 230117_WJC_METTL3_WT_vs_EV_F07.15428.15428.2 0.127 16-Sep R.ALVQSLLAK.E sp|Q9NX46|ADPRS_HUMAN 1 941.591 3.2 57741 15428 2 941.592081 471.8028 ADP-ribose glycohydrolase ARH3 OS=Homo sapiens OX=9606 GN=ADPRS PE=1 SV=1 8.8 3190.6 - 115617 - - - 1.1831 - 1.33 0.254 - 159.1 1 2 0 0.0011 9 0 0 0 1.51E+07 4.72E+06 - - - 1.7417 0.9883 230117_WJC_METTL3_WT_vs_EV_F07.15435.15435.2 0.194 12-Aug R.LIMQYLK[136.11].E sp|Q2TAY7|SMU1_HUMAN 1 915.5343 0.98 57746 15435 2 915.536778 458.7744 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.59 3191.4 - 4.10E+06 - - - 2.6946 - 1.278 0.114 - 169.6 1 2 0 0.0025 7 0 0 0 9.77E+07 9.96E+07 - - - 0.6595 0.998 230117_WJC_METTL3_WT_vs_EV_F07.15436.15436.2 0.00247 18-Sep R.LITLEEEMTK[136.11].Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1213.6355 2.53 57747 15436 2 1213.640161 607.825 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3191.5 - 483381 - - - 3.8067 - 1.543 0.358 - 210.9 1 2 0 0.0046 10 0 0 0 3.52E+07 1.39E+07 - - - 2.8944 0.9961 230117_WJC_METTL3_WT_vs_EV_F07.15439.15439.2 0.0628 12-Aug K.SEFVILR.D "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 862.4913 0.95 57748 15439 2 862.490974 432.2529 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 5.72 3191.9 - 3.02E+06 - - - -0.3235 - 1.439 0.195 - 345.6 1 2 0 -0.0003 7 0 0 0 1.03E+08 1.08E+08 - - - 1.6344 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.15440.15440.2 0.0282 18-Sep K.LVIIEGDLER.T "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1155.6499 1.44 57749 15440 2 1155.650704 578.8322 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.14 3192 - 328821 - - - 0.662 - 1.824 0.269 - 248.7 1 2 0 0.0008 10 0 0 0 3.10E+07 2.15E+07 - - - 2.7053 0.8548 230117_WJC_METTL3_WT_vs_EV_F07.15448.15448.2 0.0318 16-Aug R.AVFPSIVGR.P "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 31 944.5444 1.21 57754 15448 2 944.547212 473.2795 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 9.79 3193 - 405800 - - - 3.029 - 1.62 0.245 - 160.1 1 1 0 0.0029 9 0 0 0 1.69E+09 1.39E+09 - - - 2.2454 0.9253 230117_WJC_METTL3_WT_vs_EV_F07.15461.15461.2 11.7 12-May K.LQQLWLK.A "sp|Q9NPC8|SIX2_HUMAN,sp|Q15475|SIX1_HUMAN" 2 927.5542 2.03 57763 15461 2 927.55572 464.7844 Homeobox protein SIX2 OS=Homo sapiens OX=9606 GN=SIX2 PE=1 SV=1 8.75 3194.5 - 1.20E+06 - - - 1.6517 - 1.041 0.056 - 58.9 9 2 0 0.0015 7 0 0 0 4.06E+07 2.00E+07 - - - -0.8448 0.943 230117_WJC_METTL3_WT_vs_EV_F07.15463.15463.2 0.107 14-Jun K.NVPYVFVR.S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 992.5444 1.15 57764 15463 2 992.551969 497.2795 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3194.7 - 5.26E+06 - - - 7.6752 - 1.326 0.273 - 162.8 1 2 0 0.0076 8 0 0 0 3.49E+08 3.02E+08 - - - 1.906 0.9621 230117_WJC_METTL3_WT_vs_EV_F07.15466.15466.2 0.00376 16-Sep R.AVFPSIVGR[166.11].P "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 31 954.5526 1.21 57767 15466 2 954.554143 478.2836 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 9.79 3194.9 - 1.08E+06 - - - 1.5945 - 1.762 0.349 - 256.4 1 1 0 0.0015 9 0 0 0 1.69E+09 1.39E+09 - - - 3.257 0.8982 230117_WJC_METTL3_WT_vs_EV_F07.15467.15467.2 6.71 14-May R.LNISDPLR.L tr|A0A1W2PRW1|A0A1W2PRW1_HUMAN 1 926.5185 0.22 57768 15467 2 926.520663 464.2665 "N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase OS=Homo sapiens OX=9606 GN=GCNT2 PE=1 SV=1" 5.84 3195 - 891073 - - - 2.3011 - 1.104 0.029 - 52.1 12 2 0 0.0021 8 0 0 0 6.06E+07 2.77E+08 - - - -0.9291 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.15471.15471.2 0.00216 14-Aug R.GFTLVGMK.M "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 851.4575 0.97 57771 15471 2 851.457858 426.736 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.75 3195.3 - 2.89E+06 - - - 0.4087 - 1.617 0.297 - 236.1 1 2 0 0.0003 8 0 0 0 1.59E+09 1.64E+09 - - - 2.6839 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.15473.15473.2 0.158 18-Aug K.VLFTGVVDAR[166.11].G sp|Q14676|MDC1_HUMAN 1 1085.6109 2.34 57773 15473 2 1085.612039 543.8127 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 5.81 3195.5 - 413822 - - - 1.0814 - 1.536 0.186 - 151.5 1 2 0 0.0012 10 0 0 0 6.52E+07 2.79E+07 - - - 1.6124 1 230117_WJC_METTL3_WT_vs_EV_F07.15475.15475.2 0.000273 16-Dec K.LGEWVGLC[160.03]K.L sp|P25398|RS12_HUMAN 1 1060.5376 2.25 57774 15475 2 1060.538615 531.2761 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3195.8 - 1.13E+07 - - - 1.0023 - 2.243 0.485 - 556 1 2 0 0.0011 9 0 0 0 4.88E+08 2.17E+08 - - - 4.9599 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.15477.15477.2 0.000281 16-Nov K.LGEWVGLC[160.03]K[136.11].L sp|P25398|RS12_HUMAN 1 1068.5518 2.25 57775 15477 2 1068.553227 535.2832 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3196 - 7.71E+06 - - - 1.3804 - 2.124 0.444 - 382.5 1 2 0 0.0015 9 0 0 0 4.88E+08 2.17E+08 - - - 4.4993 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.15478.15478.2 0.0879 18-Aug K.LVIIEGDLER[166.11].T "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1165.6582 1.46 57776 15478 2 1165.658199 583.8364 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.14 3196.1 - 815204 - - - -0.0086 - 1.621 0.216 - 196.2 1 2 0 0 10 0 0 0 3.10E+07 2.13E+07 - - - 1.9847 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.15481.15481.2 0.28 12-Jul K.TSILVFK[136.11].D sp|Q9BRS2|RIOK1_HUMAN 1 814.5044 0.6 57777 15481 2 814.5075 408.2595 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 8.41 3196.5 - 2.25E+06 - - - 3.817 - 1.874 0.329 - 224.7 1 2 0 0.0031 7 0 0 0 6.88E+07 1.15E+08 - - - 3.4601 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.15483.15483.2 0.0199 20-Aug R.LVEMASSLAIR.E "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1188.6536 17.82 57779 15483 2 1188.655187 595.3341 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3196.8 - 119654 - - - 1.2981 - 1.574 0.314 - 157.9 1 2 0 0.0015 11 0 0 0 6.68E+06 3.75E+05 - - - 2.5869 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.15490.15490.2 0.0779 18-Oct K.SYLYPSTLVR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1197.6394 0.36 57782 15490 2 1197.640438 599.827 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 3197.6 - 829029 - - - 0.8884 - 1.895 0.322 - 403.6 1 2 0 0.0011 10 0 0 0 7.13E+08 1.99E+09 - - - 3.2032 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.15502.15502.2 0.0124 16-Aug R.LLDEYNLVR.S "sp|P46531|NOTC1_HUMAN,tr|A0A7P0T8U6|A0A7P0T8U6_HUMAN,tr|A0A7P0TA56|A0A7P0TA56_HUMAN,tr|A0A7P0TB20|A0A7P0TB20_HUMAN,tr|A0A7P0T8W1|A0A7P0T8W1_HUMAN" 5 1133.6081 2.45 57790 15502 2 1133.611458 567.8113 Neurogenic locus notch homolog protein 1 OS=Homo sapiens OX=9606 GN=NOTCH1 PE=1 SV=4 4.37 3199.1 - 185192 - - - 2.9852 - 1.785 0.287 - 124.3 1 2 0 0.0034 9 0 0 0 9.22E+06 3.76E+06 - - - 2.836 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.15510.15510.2 0.0367 12-Aug K.LC[160.03]TFILK.N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 893.5045 1.28 57794 15510 2 893.504703 447.7595 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3200.1 - 864500 - - - 0.2708 - 1.502 0.163 - 144.7 1 2 0 0.0002 7 0 0 0 6.83E+07 5.33E+07 - - - 1.5338 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.15512.15512.2 0.0237 12-Sep K.LC[160.03]TFILK[136.11].N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 901.5187 1.28 57796 15512 2 901.519096 451.7666 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3200.3 - 962601 - - - 0.4825 - 1.554 0.158 - 181.7 1 2 0 0.0004 7 0 0 0 6.72E+07 5.24E+07 - - - 1.6047 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.15513.15513.2 0.00113 15/20 K.IGLFGGAGVGK.T "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 974.5549 1.5 57797 15513 2 974.555068 488.2847 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 8.75 3200.4 - 866653 - - - 0.156 - 2.412 0.343 - 454 1 2 0 0.0002 11 0 0 0 4.68E+08 3.13E+08 - - - 3.9562 0.9925 230117_WJC_METTL3_WT_vs_EV_F07.15522.15522.2 0.407 12-Jun R.YAFDFAR.E "sp|Q92564|DCNL4_HUMAN,sp|Q9BTE7|DCNL5_HUMAN,tr|H0YCN4|H0YCN4_HUMAN,tr|H0Y9C5|H0Y9C5_HUMAN,tr|E9PM04|E9PM04_HUMAN,tr|H0Y907|H0Y907_HUMAN" 6 888.413 1.88 57802 15522 2 888.414825 445.2138 DCN1-like protein 4 OS=Homo sapiens OX=9606 GN=DCUN1D4 PE=1 SV=2 5.84 3201.6 - 687550 - - - 2.0508 - 1.087 0.198 - 109.4 1 2 0 0.0018 7 0 0 0 3.08E+07 1.64E+07 - - - 0.7672 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.15533.15533.2 0.151 14-Aug R.IGQFVFAR.D sp|Q9NRN7|ADPPT_HUMAN 1 936.5181 7.75 57807 15533 2 936.518817 469.2663 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2 9.75 3203.1 - 8.10E+06 - - - 0.7261 - 1.79 0.281 - 192.5 1 2 0 0.0007 8 0 0 0 2.64E+08 3.41E+07 - - - 2.8722 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.15535.15535.2 0.00176 22-Nov K.AVASAAAALVLK.A sp|Q9Y490|TLN1_HUMAN 1 1083.6652 1.06 57809 15535 2 1083.667341 542.8399 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.8 3203.3 - 617163 - - - 1.9803 - 1.799 0.367 - 267.7 1 2 0 0.0021 12 0 0 0 3.10E+07 2.94E+07 - - - 3.2961 0.9913 230117_WJC_METTL3_WT_vs_EV_F07.15547.15547.2 0.0654 12-Jun R.ALTALFK[136.11].E "sp|Q9UBB4|ATX10_HUMAN,tr|A0A1W2PQD2|A0A1W2PQD2_HUMAN" 2 770.4782 1.5 57816 15547 2 770.477676 386.2464 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 8.8 3204.5 - 1.39E+06 - - - -0.6489 - 1.187 0.21 - 130 1 2 0 -0.0005 7 0 0 0 7.17E+07 4.77E+07 - - - 1.1351 0.9953 230117_WJC_METTL3_WT_vs_EV_F07.15551.15551.2 0.344 12-Jul R.FLVTVIK.D "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 818.5266 1.37 57818 15551 2 818.527845 410.2706 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3205 - 1.57E+06 - - - 1.5503 - 1.34 0.143 - 165.4 1 2 0 0.0013 7 0 0 0 1.15E+08 8.37E+07 - - - 1.0241 0.9937 230117_WJC_METTL3_WT_vs_EV_F07.15559.15559.2 0.377 12-Jul R.ALTALFK.E "sp|Q9UBB4|ATX10_HUMAN,tr|A0A1W2PQD2|A0A1W2PQD2_HUMAN" 2 762.464 1.5 57822 15559 2 762.466336 382.2393 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 8.8 3206 - 2.57E+06 - - - 3.0952 - 1.32 0.188 - 216.3 1 2 0 0.0024 7 0 0 0 7.13E+07 4.76E+07 - - - 1.3085 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.15560.15560.2 0.0862 12-Jul K.YIQELWR.K "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1006.5236 0.82 57823 15560 2 1006.52426 504.2691 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 6 3206 - 1.15E+06 - - - 0.6398 - 1.465 0.207 - 176.2 1 2 0 0.0006 7 0 0 0 1.84E+08 2.26E+08 - - - 1.7796 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.15568.15568.2 0.0153 14-Sep R.LYNYFYDR.R "sp|Q96GD4|AURKB_HUMAN,tr|J3QR41|J3QR41_HUMAN,tr|J3QLN8|J3QLN8_HUMAN,tr|J3KTD6|J3KTD6_HUMAN,tr|J3KT86|J3KT86_HUMAN" 5 1152.524 1.75 57825 15568 2 1152.524063 577.2693 Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3 5.83 3207.3 - 561907 - - - 0.046 - 1.49 0.421 - 301.7 1 2 0 0.0001 8 0 0 0 1.35E+07 7.75E+06 - - - 3.3532 0.9933 230117_WJC_METTL3_WT_vs_EV_F07.15572.15572.2 3.16 12-Jul R.LILEALK[136.11].Q "sp|Q8IX18|DHX40_HUMAN,sp|Q6TDP4|KLH17_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|D6RJB0|D6RJB0_HUMAN,tr|H0Y9K3|H0Y9K3_HUMAN,tr|A0A3B3ISF8|A0A3B3ISF8_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN,tr|Q0VGE6|Q0VGE6_HUMAN,tr|J3QLT4|J3QLT4_HUMAN,tr|A0A3B3IT29|A0A3B3IT29_HUMAN,tr|D6R9W6|D6R9W6_HUMAN,tr|G3V0E9|G3V0E9_HUMAN" 12 806.5357 1.25 57827 15572 2 806.536149 404.2751 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 6 3207.8 - 665733 - - - 0.5679 - 1.336 0.122 - 113.4 1 2 0 0.0005 7 0 0 0 4.57E+07 3.65E+07 - - - 0.8598 0.999 230117_WJC_METTL3_WT_vs_EV_F07.15577.15577.2 0.0488 12-Aug K.YIQELWR[166.11].K "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1016.5319 0.81 57829 15577 2 1016.531835 509.2732 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 6 3208.5 - 4.58E+06 - - - -0.0502 - 1.486 0.342 - 244.6 1 2 0 -0.0001 7 0 0 0 1.84E+08 2.26E+08 - - - 2.822 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.15587.15587.2 0.024 14-Jul R.TVEDVFLR[166.11].K sp|Q96EL2|RT24_HUMAN 1 987.5265 0.97 57837 15587 2 987.528026 494.7705 "28S ribosomal protein S24, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS24 PE=1 SV=1" 4.37 3209.7 - 1.68E+06 - - - 1.5797 - 1.191 0.314 - 148.1 1 2 0 0.0016 8 0 0 0 4.82E+07 4.99E+07 - - - 1.8869 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.15588.15588.2 0.00422 14-Aug R.LLEC[160.03]YFTR[166.11].S "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1110.5407 2.91 57838 15588 2 1110.542717 556.2776 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.99 3209.8 - 619291 - - - 1.7838 - 1.527 0.377 - 197.7 1 2 0 0.002 8 0 0 0 4.36E+07 1.49E+07 - - - 3.1016 0.9573 230117_WJC_METTL3_WT_vs_EV_F07.15592.15592.2 0.267 12-Jul R.C[160.03]ILPFDK[136.11].E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 899.4666 1.36 57840 15592 2 899.467538 450.7406 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.83 3210.2 - 872150 - - - 1.015 - 1.142 0.008 - 206 1 2 0 0.0009 7 0 0 0 2.67E+08 1.96E+08 - - - -0.4795 0.9898 230117_WJC_METTL3_WT_vs_EV_F07.15594.15594.2 2.27 12-Jul R.LWISVAR[166.11].Y sp|Q15029|U5S1_HUMAN 1 853.5049 1.93 57842 15594 2 853.506252 427.7597 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 9.75 3210.4 - 2.54E+06 - - - 1.5337 - 1.348 0.064 - 215.7 1 2 0 0.0013 7 0 0 0 1.86E+08 9.66E+07 - - - 0.4595 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.15602.15602.2 0.418 14-Jul R.LLFGPTVR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 911.5468 0.94 57848 15602 2 911.547998 456.7807 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3211.4 - 1.04E+06 - - - 1.3055 - 1.232 0.24 - 129.4 1 2 0 0.0012 8 0 0 0 1.28E+08 1.37E+08 - - - 1.4425 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.15607.15607.2 1.28 14-Jul R.GLVVPVIR[166.11].N sp|P36957|ODO2_HUMAN 1 861.5675 0.97 57851 15607 2 861.568293 431.791 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3212 - 2.31E+06 - - - 0.8705 - 1.665 0.221 - 266.4 1 2 0 0.0008 8 0 0 0 1.21E+08 1.25E+08 - - - 2.2107 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.15608.15608.2 0.0122 14-Jul K.IFSGVFVK[136.11].V "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 903.5309 1.05 57852 15608 2 903.533067 452.7727 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 8.75 3212.1 - 2.33E+06 - - - 2.3541 - 1.304 0.356 - 90.6 1 2 0 0.0021 8 0 0 0 1.02E+08 9.72E+07 - - - 2.4703 1 230117_WJC_METTL3_WT_vs_EV_F07.15619.15619.2 3.88E-06 20-Nov K.WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1223.643 0.85 57859 15619 2 1223.644492 612.8288 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3213.4 - 383358 - - - 1.212 - 2.012 0.515 - 323.7 1 2 0 0.0015 11 0 0 0 8.67E+07 1.02E+08 - - - 4.7356 0.979 230117_WJC_METTL3_WT_vs_EV_F07.15624.15624.2 0.075 16-Sep R.VVLGEFGVR[166.11].N "sp|O15160|RPAC1_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 6 984.5632 7.97 57862 15624 2 984.561645 493.2889 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 5.97 3214.1 - 3.98E+06 - - - -1.5652 - 1.549 0.081 - 255.5 1 2 0 -0.0015 9 0 0 0 8.70E+08 1.09E+08 - - - 0.9048 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.15626.15626.2 3.55 14-Sep R.GLVVPVIR.N sp|P36957|ODO2_HUMAN 1 851.5593 0.97 57864 15626 2 851.559756 426.7869 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3214.3 - 3.27E+06 - - - 0.5672 - 1.661 0.233 - 403.4 1 2 0 0.0005 8 0 0 0 1.21E+08 1.25E+08 - - - 2.2921 0.999 230117_WJC_METTL3_WT_vs_EV_F07.15627.15627.2 0.506 14-Sep R.LGDLVWGK.L "sp|Q49A26|GLYR1_HUMAN,sp|Q9UBC3|DNM3B_HUMAN,tr|K7EQB2|K7EQB2_HUMAN,tr|K7ELL0|K7ELL0_HUMAN" 4 886.4913 0.61 57865 15627 2 886.492061 444.2529 Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4 5.84 3214.4 - 2.22E+06 - - - 0.9115 - 1.888 0.198 - 233 1 2 0 0.0008 8 0 0 0 6.08E+07 9.99E+07 - - - 2.4199 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.15631.15631.2 0.000137 22-Dec K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.23 57868 15631 2 1277.751947 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3214.8 - 994687 - - - 1.8423 - 2.049 0.449 - 275.7 1 2 0 0.0024 12 0 0 0 6.05E+07 4.92E+07 - - - 4.244 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.15633.15633.2 0.0218 12-Jun M.GVPAFFR[166.11].W sp|Q9H0D6|XRN2_HUMAN 1 802.4365 0.85 57869 15633 2 802.437887 402.2255 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 3215.1 - 3.39E+06 - - - 1.6923 - 1.165 0.315 - 162 1 2 0 0.0014 7 0 0 0 4.49E+08 5.30E+08 - - - 1.8511 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.15634.15634.2 0.0515 14-Jul K.FLILNPSK.R "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 930.5539 0.57 57870 15634 2 930.554622 466.2842 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 8.75 3215.1 - 1.32E+06 - - - 0.8253 - 1.485 0.361 - 125.2 1 2 0 0.0008 8 0 0 0 2.68E+07 4.66E+07 - - - 2.8997 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.15636.15636.2 0.0971 12-Jun M.GVPAFFR.W sp|Q9H0D6|XRN2_HUMAN 1 792.4283 0.85 57872 15636 2 792.429383 397.2214 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 3215.2 - 2.89E+06 - - - 1.4184 - 1.099 0.301 - 154.5 1 2 0 0.0011 7 0 0 0 4.42E+08 5.23E+08 - - - 1.5629 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.15638.15638.2 0.0063 16-Oct R.LIVNVNDLR[166.11].R sp|P25205|MCM3_HUMAN 1 1064.6218 4.09 57874 15638 2 1064.621831 533.3182 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.84 3215.4 - 1.58E+06 - - - 0.0629 - 1.706 0.353 - 313.9 1 2 0 0.0001 9 0 0 0 8.90E+07 2.18E+07 - - - 3.1936 0.9953 230117_WJC_METTL3_WT_vs_EV_F07.15647.15647.2 0.2 14-Aug R.LLPEQLIK[136.11].E "sp|Q92621|NU205_HUMAN,sp|Q8TBZ9|TEX47_HUMAN" 2 960.6099 1.96 57881 15647 2 960.609758 481.3122 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 6 3216.4 - 1.62E+06 - - - -0.1666 - 1.195 0.247 - 128.1 1 2 0 -0.0002 8 0 0 0 1.12E+08 5.70E+07 - - - 1.4026 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.15650.15650.2 0.0348 18-Oct K.ALVLTEIGPK.R sp|O14732|IMPA2_HUMAN 1 1039.6277 114.86 57884 15650 2 1039.627805 520.8211 Inositol monophosphatase 2 OS=Homo sapiens OX=9606 GN=IMPA2 PE=1 SV=1 6.05 3216.7 - 512739 - - - 0.0558 - 1.865 0.304 - 317.9 1 2 0 0.0001 10 0 0 0 1.42E+07 1.24E+05 - - - 3.026 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.15656.15656.2 0.00258 16-Aug K.LITWSPVC[160.03]R.N "sp|P07203|GPX1_HUMAN,tr|A0A2R8Y6B6|A0A2R8Y6B6_HUMAN" 2 1130.5907 2.41 57888 15656 2 1130.590317 566.3026 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 8.25 3217.4 - 852349 - - - -0.2945 - 1.76 0.347 - 186.6 1 2 0 -0.0003 9 0 0 0 2.43E+07 1.01E+07 - - - 3.2393 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.15658.15658.2 0.0115 22-Oct K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.23 57889 15658 2 1287.758753 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3217.6 - 1.36E+06 - - - 0.6911 - 1.709 0.302 - 159.1 1 2 0 0.0009 12 0 0 0 6.15E+07 5.00E+07 - - - 2.6814 0.9769 230117_WJC_METTL3_WT_vs_EV_F07.15660.15660.2 1.34 16-Jun K.FVPLLPGNR.S sp|P78527|PRKDC_HUMAN 1 1011.5866 1.04 57890 15660 2 1011.587777 506.8006 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3217.8 - 588117 - - - 1.212 - 1.161 0.059 - 134.8 1 2 0 0.0012 9 0 0 0 9.61E+07 9.24E+07 - - - -0.0917 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.15661.15661.2 0.044 16-Jul K.FVPLLPGNR[166.11].S sp|P78527|PRKDC_HUMAN 1 1021.5948 1.04 57891 15661 2 1021.596386 511.8047 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3217.9 - 1.00E+06 - - - 1.5319 - 1.438 0.177 - 188.4 1 2 0 0.0016 9 0 0 0 9.61E+07 9.23E+07 - - - 1.3987 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.15669.15669.2 0.0381 16-Oct K.LLPDTILEK[136.11].L "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1048.626 0.7 57895 15669 2 1048.625058 525.3203 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 4.37 3218.9 - 480991 - - - -0.8621 - 1.53 0.297 - 218 1 2 0 -0.0009 9 0 0 0 1.06E+08 1.52E+08 - - - 2.4647 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.15677.15677.2 0.0951 14-Aug K.YYVLNALK[136.11].H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 990.563 2.41 57899 15677 2 990.563482 496.2888 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.5 3219.9 - 4.92E+06 - - - 0.5189 - 1.218 0.412 - 149.1 1 2 0 0.0005 8 0 0 0 2.47E+08 1.03E+08 - - - 2.6786 0.999 230117_WJC_METTL3_WT_vs_EV_F07.15678.15678.2 0.0201 16-Aug K.LLPDTILEK.L "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1040.6118 0.71 57900 15678 2 1040.612574 521.3132 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 4.37 3220.1 - 1.26E+06 - - - 0.7803 - 1.477 0.309 - 141.8 1 2 0 0.0008 9 0 0 0 1.06E+08 1.50E+08 - - - 2.4513 0.9958 230117_WJC_METTL3_WT_vs_EV_F07.15680.15680.2 0.0801 14-Aug R.LLFGPTVR.L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 901.5385 0.77 57902 15680 2 901.538177 451.7765 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3220.2 - 6.22E+06 - - - -0.4004 - 1.436 0.201 - 188.9 1 2 0 -0.0004 8 0 0 0 1.29E+08 1.68E+08 - - - 1.6168 0.9795 230117_WJC_METTL3_WT_vs_EV_F07.15682.15682.2 1.8 18-May K.SYLYPSTLVR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1207.6476 0.69 57904 15682 2 1207.64801 604.8311 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 3220.5 - 0 - - - 0.3031 - 1.227 0.09 - 64 2 2 0 0.0004 10 0 0 0 3.81E+06 5.49E+06 - - - 0.1422 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.15700.15700.2 0.0377 22-Jul R.LLETC[160.03]SIALVGK.Y "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN,tr|A0A3B3ISY3|A0A3B3ISY3_HUMAN" 7 1302.7217 8.65 57915 15700 2 1302.722634 652.3681 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 5.99 3222.6 - 444500 - - - 0.6985 - 1.398 0.287 - 114.9 1 2 0 0.0009 12 0 0 0 5.44E+06 6.29E+05 - - - 2.0421 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.15704.15704.2 6.94E-05 22-Nov K.NYIQGINLVQAK.K "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1359.7511 5.02 57917 15704 2 1359.75021 680.8828 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 8.59 3223.1 - 353204 - - - -0.6178 - 1.802 0.435 - 181.4 1 2 0 -0.0008 12 0 0 0 8.11E+06 1.61E+06 - - - 3.8031 1 230117_WJC_METTL3_WT_vs_EV_F07.15705.15705.2 2.74E-05 16-Oct K.YMTDGMLLR[166.11].E "sp|Q14562|DHX8_HUMAN,sp|O60231|DHX16_HUMAN,sp|O43143|DHX15_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|F5H658|F5H658_HUMAN" 5 1108.5285 0.87 57918 15705 2 1108.52795 555.2715 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 5.84 3223.2 - 1.29E+06 - - - -0.4574 - 1.57 0.618 - 343.2 1 2 0 -0.0005 9 0 0 0 3.66E+07 4.18E+07 - - - 4.9104 0.9745 230117_WJC_METTL3_WT_vs_EV_F07.15709.15709.2 2.91 18-Aug K.LLANMVYQYK[136.11].G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1249.662 1.76 57920 15709 2 1249.663238 625.8383 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3223.7 - 189565 - - - 0.9667 - 1.172 0.051 - 176.8 1 2 0 0.0012 10 0 0 0 1.95E+07 1.11E+07 - - - -0.1397 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.15724.15724.2 0.00157 16-Aug K.YMTDGMLLR.E "sp|Q14562|DHX8_HUMAN,sp|O60231|DHX16_HUMAN,sp|O43143|DHX15_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|F5H658|F5H658_HUMAN" 5 1098.5202 0.88 57931 15724 2 1098.521396 550.2674 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 5.84 3225.3 - 1.44E+06 - - - 1.1006 - 1.301 0.462 - 169.7 1 2 0 0.0012 9 0 0 0 3.60E+07 4.08E+07 - - - 3.2142 0.9958 230117_WJC_METTL3_WT_vs_EV_F07.15726.15726.2 0.00303 18-Oct K.LLANMVYQYK.G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1241.6478 1.76 57933 15726 2 1241.643247 621.8312 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3225.5 - 509297 - - - -3.6911 - 1.948 0.456 - 311.4 1 2 0 -0.0046 10 0 0 0 1.95E+07 1.11E+07 - - - 4.2688 0.993 230117_WJC_METTL3_WT_vs_EV_F07.15727.15727.2 0.0244 16-Aug R.VLGMTLIQK.C sp|Q04760|LGUL_HUMAN 1 1001.5943 1.22 57934 15727 2 1001.597908 501.8044 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3225.6 - 437812 - - - 3.5643 - 1.592 0.147 - 143.3 1 2 0 0.0036 9 0 0 0 3.09E+07 2.53E+07 - - - 1.4709 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.15729.15729.2 0.0927 12-Jun R.GFFNGLR[166.11].T "sp|Q9Y394|DHRS7_HUMAN,tr|H0YJ66|H0YJ66_HUMAN,tr|H0YJE4|H0YJE4_HUMAN,tr|H0YJR8|H0YJR8_HUMAN" 4 819.4267 1.24 57936 15729 2 819.427465 410.7206 Dehydrogenase\reductase SDR family member 7 OS=Homo sapiens OX=9606 GN=DHRS7 PE=1 SV=1 9.75 3225.8 - 203487 - - - 0.9421 - 1.387 0.248 - 121.9 1 2 0 0.0008 7 0 0 0 7.75E+06 6.23E+06 - - - 1.9091 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.15733.15733.2 0.0125 16-Aug R.LFEGNALLR[166.11].R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1041.5847 0.87 57938 15733 2 1041.582423 521.7996 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3226.3 - 1.00E+07 - - - -2.1381 - 1.584 0.401 - 160.6 1 2 0 -0.0022 9 0 0 0 1.09E+09 1.25E+09 - - - 3.3328 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.15735.15735.2 0.00469 16-Oct R.LFEGNALLR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1031.5764 0.87 57940 15735 2 1031.579459 516.7955 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3226.5 - 7.83E+06 - - - 2.9848 - 1.864 0.445 - 364.1 1 2 0 0.0031 9 0 0 0 1.09E+09 1.25E+09 - - - 4.1284 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.15736.15736.2 0.0091 18-Nov K.LNC[160.03]FLEQDLK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1286.642 0.1 57941 15736 2 1286.644957 644.3283 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 3226.6 - 1.02E+06 - - - 2.2804 - 1.598 0.254 - 348.7 1 2 0 0.0029 10 0 0 0 3.64E+06 3.68E+07 - - - 2.2246 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.15739.15739.2 0.398 14-Sep K.MLLSLPEK.V "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 929.5256 1.15 57944 15739 2 929.526673 465.7701 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 5.75 3227 - 600667 - - - 1.1651 - 1.719 0.215 - 275 1 2 0 0.0011 8 0 0 0 1.58E+07 1.38E+07 - - - 2.2625 0.998 230117_WJC_METTL3_WT_vs_EV_F07.15740.15740.2 0.0118 18-Dec K.LIESAEELIR.D "sp|Q13217|DNJC3_HUMAN,tr|X6R9L0|X6R9L0_HUMAN" 2 1171.6449 1.83 57945 15740 2 1171.648471 586.8297 DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1 4.25 3227.2 - 563429 - - - 3.088 - 1.613 0.268 - 349.9 1 2 0 0.0036 10 0 0 0 1.06E+07 5.76E+06 - - - 2.3538 0.9894 230117_WJC_METTL3_WT_vs_EV_F07.15741.15741.2 0.456 14-Jun K.MLLSLPEK[136.11].V "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 937.5398 1.11 57946 15741 2 937.543592 469.7772 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 5.75 3227.3 - 547572 - - - 4.0553 - 1.456 0.184 - 120.8 2 2 0 0.0038 8 0 0 0 1.53E+07 1.38E+07 - - - 1.3974 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.15742.15742.2 0.00665 14-Jul R.AFLLDPDR.C sp|Q9BTY7|HGH1_HUMAN 1 945.492 0.8 57947 15742 2 945.493803 473.7533 Protein HGH1 homolog OS=Homo sapiens OX=9606 GN=HGH1 PE=1 SV=1 4.21 3227.4 - 405236 - - - 1.926 - 1.503 0.284 - 183.8 1 2 0 0.0018 8 0 0 0 1.40E+07 1.76E+07 - - - 2.3669 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.15745.15745.2 10.1 14-Aug R.SLVSGLIR[166.11].L sp|Q92616|GCN1_HUMAN 1 853.5261 1.13 57948 15745 2 853.526504 427.7703 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.47 3227.8 - 2.40E+06 - - - 0.5061 - 1.674 0.137 - 246 1 2 0 0.0004 8 0 0 0 4.55E+07 4.01E+07 - - - 1.6066 0.8951 230117_WJC_METTL3_WT_vs_EV_F07.15746.15746.2 0.000476 12-Sep L.FGDLLLK[136.11].Q "sp|Q15147|PLCB4_HUMAN,sp|Q6P2Q9|PRP8_HUMAN,tr|A0A7P0MRI8|A0A7P0MRI8_HUMAN" 3 812.4887 1.26 57949 15746 2 812.488507 407.2516 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4 PE=1 SV=3" 5.84 3228 - 547472 - - - -0.288 - 1.961 0.188 - 197.5 1 1 0 -0.0002 7 0 0 0 1.68E+08 1.32E+08 - - - 2.5634 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.15747.15747.2 0.00733 16-Oct R.VLGMTLIQK[136.11].C sp|Q04760|LGUL_HUMAN 1 1009.6085 1.22 57950 15747 2 1009.611286 505.8115 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3228.1 - 1.61E+06 - - - 2.7218 - 1.713 0.262 - 261 1 2 0 0.0027 9 0 0 0 3.09E+07 2.53E+07 - - - 2.5324 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.15748.15748.2 0.025 18-Sep K.LIESAEELIR[166.11].D "sp|Q13217|DNJC3_HUMAN,tr|X6R9L0|X6R9L0_HUMAN" 2 1181.6531 1.83 57951 15748 2 1181.656441 591.8338 DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1 4.25 3228.2 - 715563 - - - 2.8079 - 1.91 0.257 - 206.9 1 2 0 0.0033 10 0 0 0 1.06E+07 5.76E+06 - - - 2.7444 0.9939 230117_WJC_METTL3_WT_vs_EV_F07.15749.15749.2 0.723 14-Aug K.VFNLGVYR[166.11].R "sp|O60825|F262_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN" 2 976.537 0.57 57952 15749 2 976.535903 489.2758 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 8.72 3228.3 - 578641 - - - -1.0937 - 1.715 0.135 - 273.9 1 2 0 -0.0011 8 0 0 0 2.72E+07 4.80E+07 - - - 1.6646 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.15751.15751.2 9.25E-05 18-Sep R.LVPC[160.03]ILEAAK.Q "sp|Q96ER3|SAAL1_HUMAN,tr|H0YCN7|H0YCN7_HUMAN,tr|H0YEK5|H0YEK5_HUMAN,tr|J3KND1|J3KND1_HUMAN,tr|E9PMD2|E9PMD2_HUMAN,tr|E9PRZ1|E9PRZ1_HUMAN" 6 1112.6264 1.29 57954 15751 2 1112.631753 557.3205 Protein SAAL1 OS=Homo sapiens OX=9606 GN=SAAL1 PE=1 SV=2 5.99 3228.5 - 324228 - - - 4.8408 - 1.721 0.385 - 197 1 2 0 0.0054 10 0 0 0 6.73E+06 5.20E+06 - - - 3.3983 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.15755.15755.2 0.000523 16-Dec R.VPLDPLIGK.N sp|P53384|NUBP1_HUMAN 1 950.5801 1.53 57956 15755 2 950.580197 476.2973 Cytosolic Fe-S cluster assembly factor NUBP1 OS=Homo sapiens OX=9606 GN=NUBP1 PE=1 SV=2 5.81 3229.1 - 904535 - - - 0.1357 - 1.722 0.337 - 397.9 1 2 0 0.0001 9 0 0 0 6.81E+07 4.44E+07 - - - 3.1024 0.9931 230117_WJC_METTL3_WT_vs_EV_F07.15757.15757.2 0.347 12-Jul K.LVIDVIR.Y "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 826.5276 1.16 57958 15757 2 826.529326 414.2711 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.84 3229.3 - 1.06E+07 - - - 2.0411 - 1.307 0.126 - 171.5 1 2 0 0.0017 7 0 0 0 1.35E+08 1.16E+08 - - - 0.8194 0.9176 230117_WJC_METTL3_WT_vs_EV_F07.15758.15758.2 4.79 12-May K.LVIDVIR[166.11].Y "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 836.5359 2.06 57959 15758 2 836.536692 419.2752 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.84 3229.3 - 5.26E+06 - - - 0.936 - 1.092 0.033 - 62.3 11 2 0 0.0008 7 0 0 0 1.20E+08 5.82E+07 - - - -0.9018 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.15759.15759.2 0.00771 20-Sep R.VIGTLLGTVDK[136.11].H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1122.674 1.16 57960 15759 2 1122.676711 562.3443 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3229.4 - 1.23E+06 - - - 2.437 - 1.605 0.346 - 123.6 1 2 0 0.0027 11 0 0 0 9.71E+07 8.39E+07 - - - 2.8756 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.15760.15760.2 0.018 16-Aug K.LISEEDLLR.K "sp|P01106|MYC_HUMAN,tr|A0A087WUS5|A0A087WUS5_HUMAN,tr|A0A494C1T8|A0A494C1T8_HUMAN,tr|H0YBT0|H0YBT0_HUMAN" 4 1086.5921 0.22 57961 15760 2 1086.59452 544.3033 Myc proto-oncogene protein OS=Homo sapiens OX=9606 GN=MYC PE=1 SV=1 4.14 3229.6 - 1.07E+06 - - - 2.2363 - 1.347 0.355 - 164.6 1 2 0 0.0024 9 0 0 0 1.09E+07 4.95E+07 - - - 2.524 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.15762.15762.2 9.71E-05 20-Nov R.VIGTLLGTVDK.H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1114.6598 1.15 57963 15762 2 1114.664961 558.3372 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3229.8 - 862442 - - - 4.6525 - 1.921 0.477 - 208.6 1 2 0 0.0052 11 0 0 0 9.65E+07 8.39E+07 - - - 4.3286 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.15769.15769.2 0.000635 14-Sep K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 1.75 57969 15769 2 895.482612 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3230.7 - 6.97E+07 - - - 2.5216 - 1.731 0.433 - 204.2 1 2 0 0.0023 8 0 0 0 3.18E+09 1.81E+09 - - - 3.8933 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.15771.15771.2 0.0137 14-Jul K.FVADGIFK[136.11].A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 903.4946 1.75 57970 15771 2 903.495274 452.7546 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3230.9 - 5.44E+07 - - - 0.7969 - 1.46 0.34 - 129.7 1 2 0 0.0007 8 0 0 0 3.18E+09 1.81E+09 - - - 2.6934 0.869 230117_WJC_METTL3_WT_vs_EV_F07.15773.15773.2 0.103 12-Aug L.FGDLLLK.Q "sp|Q15147|PLCB4_HUMAN,sp|Q6P2Q9|PRP8_HUMAN,tr|A0A7P0MRI8|A0A7P0MRI8_HUMAN" 3 804.4745 1.27 57972 15773 2 804.474528 403.2445 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4 PE=1 SV=3" 5.84 3231 - 5.71E+06 - - - -0.0162 - 1.555 0.23 - 167.7 1 1 0 0 7 0 0 0 1.67E+08 1.32E+08 - - - 2.1386 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.15775.15775.2 0.165 14-Jul R.IAVPVLVR.D sp|P52952|NKX25_HUMAN 1 865.5749 1.98 57974 15775 2 865.57458 433.7947 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 9.75 3231.2 - 885855 - - - -0.3963 - 1.516 0.284 - 183.6 1 2 0 -0.0003 8 0 0 0 2.54E+07 1.29E+07 - - - 2.3934 0.9739 230117_WJC_METTL3_WT_vs_EV_F07.15781.15781.2 3.15 16-Jul R.FLPSPVVIK[136.11].K "sp|Q13618|CUL3_HUMAN,tr|H7C399|H7C399_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 3 1006.6307 0.61 57978 15781 2 1006.631629 504.3226 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 8.75 3231.9 - 2.33E+06 - - - 0.9686 - 1.151 0.054 - 138.9 1 2 0 0.001 9 0 0 0 6.01E+07 9.79E+07 - - - -0.1536 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.15783.15783.2 0.0512 14-Jul R.FVDGLTFK.V "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 925.4909 0.98 57980 15783 2 925.490571 463.7527 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.84 3232 - 1.49E+06 - - - -0.376 - 1.393 0.296 - 123.3 1 2 0 -0.0003 8 0 0 0 1.51E+07 1.54E+07 - - - 2.2268 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.15786.15786.2 0.222 12-Aug R.ITILLPK.R "sp|Q9BT43|RPC7L_HUMAN,tr|A6NGX6|A6NGX6_HUMAN,tr|A0A0D9SG24|A0A0D9SG24_HUMAN" 3 796.5422 2.03 57983 15786 2 796.542306 399.2784 DNA-directed RNA polymerase III subunit RPC7-like OS=Homo sapiens OX=9606 GN=POLR3GL PE=1 SV=1 8.75 3232.3 - 772308 - - - 0.1004 - 1.752 0.176 - 144.8 1 2 0 0.0001 7 0 0 0 1.86E+07 9.14E+06 - - - 2.1177 0.9952 230117_WJC_METTL3_WT_vs_EV_F07.15787.15787.2 0.0591 16-Sep R.LWGEPVNLR.E "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 1082.5873 1.13 57984 15787 2 1082.586532 542.3009 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 6 3232.4 - 576520 - - - -0.69 - 1.743 0.136 - 255 1 2 0 -0.0007 9 0 0 0 1.12E+07 9.91E+06 - - - 1.6527 0.9921 230117_WJC_METTL3_WT_vs_EV_F07.15794.15794.2 1.16 14-Jul K.NLYIISVK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 956.5786 1.32 57989 15794 2 956.579331 479.2966 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3233.3 - 1.55E+06 - - - 0.7454 - 1.398 0.087 - 162.4 1 2 0 0.0007 8 0 0 0 3.77E+09 2.86E+09 - - - 0.6938 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.15795.15795.2 0.04 14-Aug K.NLYIISVK.G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 948.5644 1.32 57990 15795 2 948.565927 475.2895 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3233.3 - 1.40E+06 - - - 1.5908 - 1.475 0.236 - 220.7 1 2 0 0.0015 8 0 0 0 3.77E+09 2.86E+09 - - - 1.9558 0.994 230117_WJC_METTL3_WT_vs_EV_F07.15801.15801.2 0.095 12-Jun K.FVSELWK[136.11].D sp|P35579|MYH9_HUMAN 1 915.4946 0.6 57994 15801 2 915.493168 458.7546 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6 3234 - 4.69E+06 - - - -1.5139 - 1.329 0.269 - 97.1 1 2 0 -0.0014 7 0 0 0 1.10E+08 1.86E+08 - - - 1.9286 0.9953 230117_WJC_METTL3_WT_vs_EV_F07.15803.15803.2 0.217 14-Aug K.TAVLTLIR.E "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 8 885.5648 1.5 57996 15803 2 885.565572 443.7897 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 9.41 3234.1 - 1.34E+06 - - - 0.9248 - 1.636 0.07 - 329.5 1 2 0 0.0008 8 0 0 0 1.55E+08 1.03E+08 - - - 1.0424 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.15804.15804.2 0.0292 14-Jul R.LLPSLIGR[166.11].H "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 4 877.5625 0.77 57997 15804 2 877.562574 439.7885 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 9.75 3234.2 - 914510 - - - 0.1322 - 1.427 0.328 - 178.5 1 2 0 0.0001 8 0 0 0 7.07E+07 9.22E+07 - - - 2.536 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.15806.15806.2 7.28E-05 20-Oct R.LFSGDVVLTAR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1186.6585 0.98 57999 15806 2 1186.659518 594.3365 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3234.4 - 415763 - - - 0.8216 - 1.899 0.456 - 274.4 1 2 0 0.001 11 0 0 0 1.92E+08 1.96E+08 - - - 4.1437 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.15809.15809.2 0.0266 14-Jul R.LFC[160.03]VGFTK[136.11].K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 978.5088 0.84 58000 15809 2 978.509791 490.2617 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.22 3234.8 - 2.20E+06 - - - 0.9882 - 1.372 0.353 - 159.1 1 2 0 0.001 8 0 0 0 3.73E+08 4.43E+08 - - - 2.6018 0.999 230117_WJC_METTL3_WT_vs_EV_F07.15810.15810.2 0.0152 14-Jun R.LFC[160.03]VGFTK.K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 970.4946 0.84 58001 15810 2 970.49524 486.2546 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.22 3234.9 - 1.25E+06 - - - 0.6347 - 1.38 0.332 - 119.5 1 2 0 0.0006 8 0 0 0 3.73E+08 4.44E+08 - - - 2.4643 0.9386 230117_WJC_METTL3_WT_vs_EV_F07.15819.15819.2 2.77 12-May K.VLFTC[160.03]FK[136.11].R "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 921.4874 1.78 58008 15819 2 921.487685 461.751 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 8.19 3235.9 - 1.07E+06 - - - 0.3516 - 0.977 0.088 - 51.1 3 2 0 0.0003 7 0 0 0 2.34E+07 1.31E+07 - - - -0.596 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.15820.15820.2 0.198 14-Jul R.LLPSLIGR.H "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 4 867.5542 0.76 58009 15820 2 867.553829 434.7844 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 9.75 3236 - 854748 - - - -0.4138 - 1.37 0.251 - 175.7 1 2 0 -0.0004 8 0 0 0 7.04E+07 9.22E+07 - - - 1.8442 1 230117_WJC_METTL3_WT_vs_EV_F07.15821.15821.2 0.000107 13/20 R.LFSGDVVLTAR.D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1176.6503 0.98 58010 15821 2 1176.654263 589.3324 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3236.1 - 562756 - - - 3.391 - 2.416 0.509 - 560.3 1 2 0 0.004 11 0 0 0 1.92E+08 1.96E+08 - - - 5.1855 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.15823.15823.2 0.102 18-Sep R.IVLVDDSIVR.G sp|Q06203|PUR1_HUMAN 1 1127.655 1.85 58012 15823 2 1127.658171 564.8348 Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1 4.21 3236.3 - 576363 - - - 2.7907 - 1.59 0.272 - 185 1 2 0 0.0031 10 0 0 0 4.65E+07 2.51E+07 - - - 2.3434 1 230117_WJC_METTL3_WT_vs_EV_F07.15825.15825.2 2.10E-06 26-Oct K.VLEQLTGQTPVFSK[136.11].A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1553.8545 1.37 58014 15825 2 1553.855969 777.9345 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3236.6 - 163202 - - - 0.9718 - 2.086 0.537 - 247.1 1 2 0 0.0015 14 0 0 0 6.85E+06 5.00E+06 - - - 4.8519 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.15828.15828.2 0.000733 18-Oct R.IVLVDDSIVR[166.11].G sp|Q06203|PUR1_HUMAN 1 1137.6633 1.85 58015 15828 2 1137.664273 569.8389 Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1 4.21 3237 - 572233 - - - 0.8605 - 1.762 0.449 - 282.9 1 2 0 0.001 10 0 0 0 4.65E+07 2.51E+07 - - - 3.9381 0.9951 230117_WJC_METTL3_WT_vs_EV_F07.15831.15831.2 0.0326 16-Oct K.EALEAVLIK[136.11].G "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 992.5997 1.81 58018 15831 2 992.605057 497.3072 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 4.53 3237.4 - 420640 - - - 5.3486 - 1.85 0.305 - 231.1 1 2 0 0.0053 9 0 0 0 2.30E+07 1.27E+07 - - - 3.0718 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.15832.15832.2 8.96E-06 16-Oct K.LDELYGTWR[166.11].K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1161.5694 4.12 58019 15832 2 1161.568949 581.792 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 4.37 3237.5 - 324346 - - - -0.3831 - 2.264 0.397 - 352.8 1 2 0 -0.0004 9 0 0 0 3.17E+07 7.69E+06 - - - 4.3371 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.15835.15835.2 0.0594 14-Sep R.TVETLLLR.F "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 6 943.5702 0.5 58020 15835 2 943.572303 472.7924 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 5.66 3237.9 - 4.06E+06 - - - 2.1949 - 1.469 0.255 - 247 1 2 0 0.0021 8 0 0 0 9.83E+07 1.98E+08 - - - 2.0837 0.965 230117_WJC_METTL3_WT_vs_EV_F07.15837.15837.2 0.509 14-Jun K.AVIELLEK[136.11].S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|H0Y327|H0Y327_HUMAN,tr|Q5JYA8|Q5JYA8_HUMAN,tr|Q5JYA3|Q5JYA3_HUMAN" 6 921.5626 2.54 58022 15837 2 921.56152 461.7886 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.53 3238.1 - 1.08E+06 - - - -1.2088 - 1.474 0.04 - 77.8 2 2 0 -0.0011 8 0 0 0 5.60E+07 2.20E+07 - - - 0.3717 0.999 230117_WJC_METTL3_WT_vs_EV_F07.15839.15839.2 0.000299 22-Oct R.VLVTGATGLLGR[166.11].A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1165.7058 1.52 58024 15839 2 1165.704169 583.8602 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3238.4 - 483521 - - - -1.4232 - 1.832 0.49 - 245.9 1 2 0 -0.0017 12 0 0 0 2.92E+07 1.92E+07 - - - 4.2526 1 230117_WJC_METTL3_WT_vs_EV_F07.15840.15840.2 5.60E-05 26-Oct K.VLEQLTGQTPVFSK.A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1545.8403 1.37 58025 15840 2 1545.843107 773.9274 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3238.5 - 434101 - - - 1.8424 - 2.27 0.481 - 207.3 1 2 0 0.0028 14 0 0 0 6.85E+06 5.00E+06 - - - 4.65 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.15846.15846.2 0.0652 16-Aug R.FFMGNQVLK[136.11].V sp|P13010|XRCC5_HUMAN 1 1090.5725 0.76 58029 15846 2 1090.575431 546.2935 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3239.2 - 940683 - - - 2.6995 - 1.422 0.253 - 131.7 1 2 0 0.0029 9 0 0 0 6.88E+07 9.02E+07 - - - 1.9273 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.15851.15851.2 0.00174 22-Jul R.VLVTGATGLLGR.A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1155.6976 1.52 58032 15851 2 1155.698553 578.8561 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3239.8 - 482588 - - - 0.861 - 1.538 0.366 - 111.8 2 2 0 0.001 12 0 0 0 2.92E+07 1.92E+07 - - - 2.7422 0.9634 230117_WJC_METTL3_WT_vs_EV_F07.15852.15852.2 0.224 16-Aug K.LIPPQDILR[166.11].D sp|Q96A65|EXOC4_HUMAN 1 1073.6472 1.85 58033 15852 2 1073.645694 537.8309 Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1 5.84 3239.9 - 212102 - - - -1.4493 - 1.377 0.065 - 154.8 1 2 0 -0.0016 9 0 0 0 2.21E+07 1.19E+07 - - - 0.4461 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.15853.15853.2 0.0102 14-Jul R.ELYPVEFR.N "sp|Q5BJF2|SGMR2_HUMAN,tr|J3KT68|J3KT68_HUMAN" 2 1051.5338 1.17 58034 15853 2 1051.533188 526.7742 Sigma intracellular receptor 2 OS=Homo sapiens OX=9606 GN=TMEM97 PE=1 SV=1 4.53 3240.1 - 624009 - - - -0.6258 - 1.384 0.366 - 209.9 1 2 0 -0.0007 8 0 0 0 2.58E+07 2.21E+07 - - - 2.7242 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.15854.15854.2 0.0057 18-Sep R.LVPLQEEIYR.K "sp|Q2NKX8|ERC6L_HUMAN,tr|B5MDQ0|B5MDQ0_HUMAN" 2 1258.6921 3.58 58035 15854 2 1258.693393 630.3533 DNA excision repair protein ERCC-6-like OS=Homo sapiens OX=9606 GN=ERCC6L PE=1 SV=1 4.53 3240.2 - 206153 - - - 0.9971 - 1.637 0.325 - 384.4 1 2 0 0.0013 10 0 0 0 9.06E+06 2.53E+06 - - - 2.8168 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.15858.15858.2 0.000962 16-Oct K.EALEAVLIK.G "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 984.5855 1.81 58036 15858 2 984.584222 493.3001 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 4.53 3240.8 - 705347 - - - -1.3468 - 1.758 0.389 - 209 1 2 0 -0.0013 9 0 0 0 2.30E+07 1.27E+07 - - - 3.5459 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.15872.15872.2 0.0324 14-Jul K.EMVELPLR[166.11].H "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN" 10 995.5349 0.86 58043 15872 2 995.536817 498.7747 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.53 3242.6 - 776540 - - - 1.9025 - 1.432 0.28 - 150.6 1 2 0 0.0019 8 0 0 0 1.65E+07 1.93E+07 - - - 2.1914 0.9812 230117_WJC_METTL3_WT_vs_EV_F07.15874.15874.2 2.17 14-Apr K.LVWIPSER.H "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 998.5549 0.4 58044 15874 2 998.556076 500.2847 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3242.8 - 1.07E+06 - - - 1.1617 - 0.991 0.14 - 57.9 1 2 0 0.0012 8 0 0 0 4.49E+07 1.12E+08 - - - 0.0474 0.999 230117_WJC_METTL3_WT_vs_EV_F07.15875.15875.2 0.0034 18-Oct R.GLIENPALLR[166.11].W sp|O95168|NDUB4_HUMAN 1 1104.6531 1.42 58045 15875 2 1104.652148 553.3338 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3 6 3243 - 1.03E+06 - - - -0.8292 - 2.216 0.308 - 254.3 1 2 0 -0.0009 10 0 0 0 4.66E+07 3.28E+07 - - - 3.5367 0.9966 230117_WJC_METTL3_WT_vs_EV_F07.15876.15876.2 0.473 12-Jul R.VLAAFLR.R "sp|Q9HB09|B2L12_HUMAN,sp|Q99607|ELF4_HUMAN,tr|M0R1Z8|M0R1Z8_HUMAN,tr|A0A087WU18|A0A087WU18_HUMAN,tr|I6LJZ9|I6LJZ9_HUMAN,tr|A0A087WSV0|A0A087WSV0_HUMAN,tr|I6LK00|I6LK00_HUMAN,tr|I6LJZ7|I6LJZ7_HUMAN,tr|M0R1K0|M0R1K0_HUMAN,tr|M0QZM6|M0QZM6_HUMAN" 10 788.4909 3.52 58046 15876 2 788.491241 395.2527 Bcl-2-like protein 12 OS=Homo sapiens OX=9606 GN=BCL2L12 PE=1 SV=1 9.72 3243 - 1.67E+06 - - - 0.4845 - 1.552 0.133 - 181.8 1 2 0 0.0004 7 0 0 0 3.55E+07 1.01E+07 - - - 1.4159 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.15888.15888.3 8.86E-09 19/64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 22.63 58053 15888 3 1786.987587 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3244.6 - 326104 - - - 2.6229 - 3.566 0.465 - 340.2 1 2 0 0.0047 17 0 0 0 5.68E+07 2.51E+06 - - - 6.935 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.15889.15889.2 0.393 14-Jul K.EMVELPLR.H "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN" 10 985.5267 0.83 58054 15889 2 985.528324 493.7706 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.53 3244.6 - 476435 - - - 1.6955 - 1.428 0.205 - 130.2 1 2 0 0.0017 8 0 0 0 1.74E+07 2.09E+07 - - - 1.6291 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.15890.15890.2 0.394 12-Jul K.AFLFVNK.G sp|Q8N0X7|SPART_HUMAN 1 837.4749 1.39 58055 15890 2 837.477493 419.7447 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3244.7 - 9.63E+06 - - - 3.1261 - 1.434 0.229 - 224.9 1 2 0 0.0026 7 0 0 0 2.15E+08 1.55E+08 - - - 1.8737 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.15894.15894.2 0.0568 18-Sep R.GLIENPALLR.W sp|O95168|NDUB4_HUMAN 1 1094.6448 1.42 58057 15894 2 1094.645964 548.3297 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3 6 3245.2 - 1.31E+06 - - - 1.0688 - 1.807 0.17 - 190.3 1 2 0 0.0012 10 0 0 0 4.66E+07 3.28E+07 - - - 1.9478 0.9684 230117_WJC_METTL3_WT_vs_EV_F07.15895.15895.2 0.933 12-Jul K.SIELFYK[136.11].F sp|P78527|PRKDC_HUMAN 1 906.4942 1.03 58058 15895 2 906.494201 454.2544 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.72 3245.3 - 1.39E+06 - - - -0.021 - 1.055 0.101 - 163.9 1 2 0 0 7 0 0 0 3.30E+07 3.21E+07 - - - -0.0434 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.15896.15896.2 0.012 12-Jul K.AFLFVNK[136.11].G sp|Q8N0X7|SPART_HUMAN 1 845.4891 1.39 58059 15896 2 845.49077 423.7518 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3245.4 - 6.91E+06 - - - 2.0048 - 1.394 0.238 - 215.2 1 2 0 0.0017 7 0 0 0 2.18E+08 1.57E+08 - - - 1.8509 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.15897.15897.2 0.166 14-Jul K.FVIPLHSA.- sp|Q96F86|EDC3_HUMAN 1 882.4963 - 58060 15897 2 882.498712 442.2554 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 6.74 3245.5 - 2.15E+06 - - - 2.689 - 1.405 0.259 - 178.6 1 2 0 0.0024 8 0 0 0 - - - - - 1.9788 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.15898.15898.2 0.194 16-Sep R.ILPQDVILK[136.11].F "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1045.6627 1.16 58061 15898 2 1045.665365 523.8386 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.84 3245.6 - 924031 - - - 2.5658 - 1.533 0.233 - 166.8 1 2 0 0.0027 9 0 0 0 2.22E+07 1.93E+07 - - - 1.9971 0.997 230117_WJC_METTL3_WT_vs_EV_F07.15899.15899.2 0.952 16-Sep R.ILPQDVILK.F "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1037.6485 1.2 58062 15899 2 1037.650833 519.8315 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.84 3245.7 - 824844 - - - 2.2657 - 1.532 0.171 - 186.6 1 2 0 0.0024 9 0 0 0 2.38E+07 1.98E+07 - - - 1.5374 0.985 230117_WJC_METTL3_WT_vs_EV_F07.15905.15905.2 0.468 12-Jul R.SVINLLR.N "sp|Q96AT9|RPE_HUMAN,sp|Q2QD12|RPEL1_HUMAN,tr|C9J6A7|C9J6A7_HUMAN" 3 813.5072 1.72 58066 15905 2 813.510143 407.7609 Ribulose-phosphate 3-epimerase OS=Homo sapiens OX=9606 GN=RPE PE=1 SV=1 9.47 3246.6 - 389206 - - - 3.571 - 1.242 0.155 - 140.3 1 2 0 0.0029 7 0 0 0 1.70E+07 9.88E+06 - - - 0.8716 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.15910.15910.3 0.00368 Oct-64 R.IINEPTAAAIAYGLDK[136.11]K[136.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1803.0113 22.63 58071 15910 3 1803.01777 602.011 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3247.2 - 212925 - - - 3.5884 - 2.059 0.289 - 84.5 1 2 0 0.0065 17 0 0 0 5.68E+07 2.51E+06 - - - 3.5848 0.8944 230117_WJC_METTL3_WT_vs_EV_F07.15918.15918.2 7.96 14-Jun K.GLVAVGER.A "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 3 799.4552 1.23 58077 15918 2 799.457755 400.7349 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3248 - 534924 - - - 3.1934 - 1.107 0.052 - 87.6 7 2 0 0.0026 8 0 0 0 1.98E+07 1.61E+07 - - - -0.6467 0.9765 230117_WJC_METTL3_WT_vs_EV_F07.15925.15925.2 2.71 14-May R.VILLDVAR.G sp|Q9H2M9|RBGPR_HUMAN 1 897.5648 1.35 58083 15925 2 897.5661 449.7897 Rab3 GTPase-activating protein non-catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP2 PE=1 SV=1 5.81 3248.7 - 1.41E+06 - - - 1.5007 - 1.134 0.101 - 66.8 4 2 0 0.0013 8 0 0 0 1.59E+07 1.18E+07 - - - -0.1031 0.9889 230117_WJC_METTL3_WT_vs_EV_F07.15931.15931.2 1.14 12-Jun R.VLQLFTR.L "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 875.5229 0.99 58089 15931 2 875.522675 438.7687 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 9.72 3249.1 - 837505 - - - -0.2433 - 1.348 0.106 - 100.3 1 2 0 -0.0002 7 0 0 0 4.60E+07 4.62E+07 - - - 0.77 0.999 230117_WJC_METTL3_WT_vs_EV_F07.15936.15936.2 0.0948 16-Aug R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 0.74 58092 15936 2 960.611449 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3249.7 - 9.26E+06 - - - 1.5938 - 1.487 0.297 - 197.6 1 2 0 0.0015 9 0 0 0 1.65E+10 2.22E+10 - - - 2.382 0.9337 230117_WJC_METTL3_WT_vs_EV_F07.15937.15937.2 0.0604 14-Aug N.IIEEALIR.R "sp|Q96EQ8|RN125_HUMAN,sp|P78527|PRKDC_HUMAN" 2 955.5702 21.19 58093 15937 2 955.5712 478.7924 E3 ubiquitin-protein ligase RNF125 OS=Homo sapiens OX=9606 GN=RNF125 PE=1 SV=4 4.53 3249.8 - 6.00E+06 - - - 1.013 - 1.659 0.266 - 189.4 1 1 0 0.001 8 0 0 0 1.47E+09 6.92E+07 - - - 2.5321 0.9844 230117_WJC_METTL3_WT_vs_EV_F07.15940.15940.2 0.26 12-Jun R.VLQLFTR[166.11].L "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 885.5312 1 58096 15940 2 885.53016 443.7729 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 9.72 3250 - 881298 - - - -1.127 - 1.186 0.182 - 119.4 1 2 0 -0.001 7 0 0 0 4.61E+07 4.60E+07 - - - 0.9255 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.15943.15943.2 0.0408 20-Jul K.FSPAGPVLSIR.V "sp|Q13310|PABP4_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN" 4 1142.6448 1.23 58099 15943 2 1142.648082 572.3297 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.75 3250.3 - 185179 - - - 2.8775 - 1.414 0.348 - 111.9 1 2 0 0.0033 11 0 0 0 1.32E+07 1.07E+07 - - - 2.5475 0.9943 230117_WJC_METTL3_WT_vs_EV_F07.15945.15945.2 0.0574 20-Sep K.ALILVGGYGTR.L "sp|Q9Y5P6|GMPPB_HUMAN,tr|A0A7I2V691|A0A7I2V691_HUMAN,tr|A0A7I2V2Y5|A0A7I2V2Y5_HUMAN,tr|A0A7I2YQI5|A0A7I2YQI5_HUMAN,tr|A0A7I2V4B5|A0A7I2V4B5_HUMAN" 5 1118.6448 0.4 58100 15945 2 1118.642319 560.3297 Mannose-1-phosphate guanyltransferase beta OS=Homo sapiens OX=9606 GN=GMPPB PE=1 SV=2 8.79 3250.5 - 442833 - - - -2.2125 - 1.75 0.253 - 168.5 1 2 0 -0.0025 11 0 0 0 9.14E+06 2.27E+07 - - - 2.4228 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.15957.15957.2 0.0337 14-Jul K.YFEYIMAK.E sp|P13674|P4HA1_HUMAN 1 1063.5049 2.61 58109 15957 2 1063.504361 532.7597 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3251.8 - 1.35E+06 - - - -0.4636 - 1.46 0.346 - 127.8 1 2 0 -0.0005 8 0 0 0 7.13E+07 2.73E+07 - - - 2.7377 0.9963 230117_WJC_METTL3_WT_vs_EV_F07.15960.15960.2 0.278 22-Aug K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.33 58112 15960 2 1277.748659 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3252 - 370099 - - - -0.731 - 1.581 0.226 - 133.6 1 2 0 -0.0009 12 0 0 0 2.49E+06 1.87E+06 - - - 1.9152 0.9876 230117_WJC_METTL3_WT_vs_EV_F07.15965.15965.2 0.726 12-Jul K.ILIWSGR.F "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 843.4967 1.52 58115 15965 2 843.495896 422.7556 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 9.75 3252.7 - 916521 - - - -0.9212 - 1.366 0.131 - 161.8 1 2 0 -0.0008 7 0 0 0 1.47E+08 9.69E+07 - - - 0.9966 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.15966.15966.2 0.00025 14-Sep K.YFEYIMAK[136.11].E sp|P13674|P4HA1_HUMAN 1 1071.5191 2.59 58116 15966 2 1071.521739 536.7668 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3252.8 - 900136 - - - 2.5058 - 1.717 0.458 - 240.1 1 2 0 0.0027 8 0 0 0 7.01E+07 2.71E+07 - - - 4.0533 0.993 230117_WJC_METTL3_WT_vs_EV_F07.15967.15967.2 0.225 14-Sep K.GIAYIEFK.T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 939.5066 0.83 58117 15967 2 939.508118 470.7606 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3253 - 671856 - - - 1.6487 - 1.363 0.104 - 206.9 1 2 0 0.0015 8 0 0 0 9.43E+08 1.14E+09 - - - 0.7427 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.15973.15973.2 0.028 18-Sep K.AFADSSYLLR[166.11].H "sp|Q9H5H4|ZN768_HUMAN,tr|H3BS42|H3BS42_HUMAN" 2 1151.585 0.78 58121 15973 2 1151.586407 576.7998 Zinc finger protein 768 OS=Homo sapiens OX=9606 GN=ZNF768 PE=1 SV=2 5.88 3253.6 - 602942 - - - 1.1836 - 1.214 0.295 - 175.7 1 2 0 0.0014 10 0 0 0 1.89E+07 2.41E+07 - - - 1.7607 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.15980.15980.2 0.00183 18-Aug K.IGDLGLATLK.R "sp|Q9H4A3|WNK1_HUMAN,sp|Q96J92|WNK4_HUMAN,sp|Q9Y3S1|WNK2_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A6PVV2|A6PVV2_HUMAN,tr|K7ENT7|K7ENT7_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 9 999.5964 2.36 58125 15980 2 999.598145 500.8055 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 5.84 3254.5 - 1.07E+06 - - - 1.6987 - 2.029 0.367 - 122.3 1 2 0 0.0017 10 0 0 0 1.21E+08 5.13E+07 - - - 3.7261 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.15982.15982.2 0.00783 16-Sep R.VFNPYTEFK.E sp|Q96C19|EFHD2_HUMAN 1 1143.5601 1.63 58127 15982 2 1143.560634 572.7873 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 5.97 3254.8 - 743509 - - - 0.5011 - 1.365 0.221 - 206 1 2 0 0.0006 9 0 0 0 3.66E+07 2.24E+07 - - - 1.5733 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.15994.15994.2 0.55 18-Sep R.LGFVAGVINR[166.11].E "sp|Q93050|VPP1_HUMAN,tr|K7EN36|K7EN36_HUMAN,tr|K7EPG4|K7EPG4_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 5 1054.6163 1.81 58135 15994 2 1054.619567 528.3154 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 9.75 3256.2 - 817371 - - - 3.113 - 1.837 0.206 - 203.1 1 2 0 0.0033 10 0 0 0 2.78E+07 1.54E+07 - - - 2.259 0.9664 230117_WJC_METTL3_WT_vs_EV_F07.15995.15995.2 0.259 14-Jul K.EVPLVFPK.T sp|Q9Y305|ACOT9_HUMAN 1 927.543 3.68 58136 15995 2 927.53919 464.7788 "Acyl-coenzyme A thioesterase 9, mitochondrial OS=Homo sapiens OX=9606 GN=ACOT9 PE=1 SV=2" 6.1 3256.3 - 746746 - - - -4.058 - 1.436 0.224 - 127.8 1 2 0 -0.0038 8 0 0 0 1.64E+07 4.44E+06 - - - 1.7856 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.15999.15999.2 0.0754 12-Aug R.LYDGLFK.V "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 10 854.4538 1.91 58138 15999 2 854.454057 428.2342 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.83 3256.7 - 2.10E+06 - - - 0.2949 - 1.329 0.251 - 143.5 1 2 0 0.0003 7 0 0 0 3.69E+08 1.94E+08 - - - 1.796 0.998 230117_WJC_METTL3_WT_vs_EV_F07.16000.16000.2 0.000364 16-Jul K.VLPVGVLYK.V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 986.6165 0.56 58139 16000 2 986.614894 494.3155 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3256.8 - 471280 - - - -1.5812 - 1.564 0.383 - 108.6 1 2 0 -0.0016 9 0 0 0 1.79E+08 3.20E+08 - - - 3.1633 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.16021.16021.2 0.037 16-Aug R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 0.74 58152 16021 2 952.59681 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3259.5 - 1.50E+08 - - - 1.1463 - 1.378 0.246 - 210.5 1 2 0 0.0011 9 0 0 0 1.65E+10 2.22E+10 - - - 1.7852 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.16023.16023.2 0.000888 20-Dec R.ILMVGLDAAGK.T "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|F5H1V1|F5H1V1_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|F5H6T5|F5H6T5_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|F8WDB3|F8WDB3_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 11 1086.6107 1.66 58153 16023 2 1086.611808 544.3126 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3259.7 - 3.58E+06 - - - 1.004 - 2.148 0.399 - 414.7 1 2 0 0.0011 11 0 0 0 2.87E+08 1.73E+08 - - - 4.0559 0.9879 230117_WJC_METTL3_WT_vs_EV_F07.16027.16027.2 0.412 18-Jul R.LAWGQPVGLR[166.11].H "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQX9|A0A0U1RQX9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 7 1105.6272 2.43 58156 16027 2 1105.626978 553.8209 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 9.75 3260 - 1.47E+06 - - - -0.1854 - 1.211 0.15 - 124.3 1 2 0 -0.0002 10 0 0 0 1.36E+08 5.59E+07 - - - 0.6832 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.16029.16029.2 0.0095 14-Aug K.GIAYIEFK[136.11].T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 947.5208 0.83 58157 16029 2 947.519896 474.7677 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3260.2 - 3.54E+07 - - - -0.9214 - 1.563 0.277 - 204 1 2 0 -0.0009 8 0 0 0 9.38E+08 1.14E+09 - - - 2.4336 0.9835 230117_WJC_METTL3_WT_vs_EV_F07.16036.16036.2 2.2 12-Aug R.LLLLDC[160.03]R.S sp|Q99956|DUS9_HUMAN 1 901.5055 2.8 58160 16036 2 901.504308 451.76 Dual specificity protein phosphatase 9 OS=Homo sapiens OX=9606 GN=DUSP9 PE=1 SV=1 5.83 3261.2 - 584950 - - - -1.3477 - 1.485 0.094 - 218.2 1 2 0 -0.0012 7 0 0 0 3.22E+07 1.15E+07 - - - 0.9878 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.16038.16038.2 0.0386 16-Oct R.LLLQLEATK.N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1027.6277 6.47 58162 16038 2 1027.624839 514.8211 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3261.4 - 578150 - - - -2.8298 - 2.006 0.348 - 266 1 2 0 -0.0029 9 0 0 0 5.23E+08 8.08E+07 - - - 3.6244 0.9926 230117_WJC_METTL3_WT_vs_EV_F07.16039.16039.2 0.251 14-Sep R.TAYLLYYR[166.11].R sp|Q14694|UBP10_HUMAN 1 1071.5629 1.02 58163 16039 2 1071.562925 536.7887 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.16 3261.6 - 356603 - - - 0.0681 - 1.235 0.171 - 235.8 1 2 0 0.0001 8 0 0 0 5.43E+07 5.31E+07 - - - 0.9406 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.16052.16052.2 7.64E-05 16-Oct R.MNVLADALK[136.11].S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 981.5409 1.31 58169 16052 2 981.539551 491.7777 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3263.2 - 2.88E+06 - - - -1.3265 - 1.964 0.447 - 310.4 1 2 0 -0.0013 9 0 0 0 5.79E+08 4.41E+08 - - - 4.2949 0.9842 230117_WJC_METTL3_WT_vs_EV_F07.16054.16054.2 0.843 12-Jul R.LFFVGSR[166.11].E "sp|Q9UM01|YLAT1_HUMAN,sp|Q92536|YLAT2_HUMAN,sp|Q01650|LAT1_HUMAN,tr|H0YJ95|H0YJ95_HUMAN,tr|A0A0C4DGL4|A0A0C4DGL4_HUMAN,tr|G3V4Z6|G3V4Z6_HUMAN" 6 834.4627 0.9 58170 16054 2 834.460896 418.2386 Y+L amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A7 PE=1 SV=2 9.75 3263.4 - 2.37E+06 - - - -2.2146 - 1.432 0.173 - 179.9 1 2 0 -0.0018 7 0 0 0 5.19E+07 5.75E+07 - - - 1.4559 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.16064.16064.2 0.415 16-Aug R.LLLQLEATK[136.11].N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1035.6419 6.51 58174 16064 2 1035.642125 518.8282 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3264.8 - 2.03E+06 - - - 0.1719 - 1.83 0.314 - 141.4 1 2 0 0.0002 9 0 0 0 5.23E+08 8.03E+07 - - - 3.1085 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.16065.16065.2 0.0209 18-Aug K.ILPEEITNLR.N sp|Q9H9A6|LRC40_HUMAN 1 1196.6765 0.92 58175 16065 2 1196.677372 599.3455 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3264.9 - 493062 - - - 0.7387 - 1.489 0.301 - 198.8 1 2 0 0.0009 10 0 0 0 4.56E+07 4.94E+07 - - - 2.3751 0.9913 230117_WJC_METTL3_WT_vs_EV_F07.16066.16066.2 1.25 12-Jul K.ILIEDWK.K "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A7I2V2T6|A0A7I2V2T6_HUMAN,tr|K7EPW7|K7EPW7_HUMAN" 4 915.5066 1.21 58176 16066 2 915.507924 458.7606 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 4.37 3265.1 - 1.27E+06 - - - 1.4801 - 1.367 0.073 - 139.2 1 2 0 0.0014 7 0 0 0 6.07E+07 5.00E+07 - - - 0.5703 1 230117_WJC_METTL3_WT_vs_EV_F07.16071.16071.2 2.95E-05 16-Oct R.MNVLADALK.S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 973.5267 1.31 58180 16071 2 973.52407 487.7706 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3265.7 - 3.66E+06 - - - -2.6532 - 2.143 0.453 - 435.9 1 2 0 -0.0026 9 0 0 0 5.79E+08 4.41E+08 - - - 4.5912 0.9922 230117_WJC_METTL3_WT_vs_EV_F07.16077.16077.2 0.153 12-Jun R.LYDGLFK[136.11].V "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 10 862.468 1.9 58184 16077 2 862.467286 432.2413 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.83 3266.3 - 3.47E+06 - - - -0.8337 - 1.355 0.178 - 80.6 1 2 0 -0.0007 7 0 0 0 3.70E+08 1.94E+08 - - - 1.3181 0.996 230117_WJC_METTL3_WT_vs_EV_F07.16079.16079.2 0.103 14-Aug R.GLVGIEFK.E sp|P15924|DESP_HUMAN 1 861.496 11.87 58185 16079 2 861.49567 431.7553 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 3266.5 - 2.77E+06 - - - -0.3877 - 1.412 0.213 - 165.3 1 2 0 -0.0003 8 0 0 0 2.90E+08 2.44E+07 - - - 1.6546 0.998 230117_WJC_METTL3_WT_vs_EV_F07.16081.16081.2 0.0495 16-Sep K.AGIPVYAWK[136.11].G sp|P23526|SAHH_HUMAN 1 1011.5633 75.38 58187 16081 2 1011.56284 506.7889 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 8.63 3266.7 - 1.35E+06 - - - -0.4567 - 1.525 0.284 - 151.6 1 2 0 -0.0005 9 0 0 0 6.92E+09 9.18E+07 - - - 2.3593 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.16089.16089.2 0.00259 18-Jul R.GYFEYIEENK.Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1290.5768 1.07 58192 16089 2 1290.578006 646.2957 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3267.8 - 310151 - - - 0.9089 - 1.642 0.428 - 82.8 1 2 0 0.0012 10 0 0 0 1.26E+07 1.17E+07 - - - 3.5861 0.9948 230117_WJC_METTL3_WT_vs_EV_F07.16093.16093.2 0.0125 14-Aug K.AVWLPAVK.A "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 882.5327 1.26 58194 16093 2 882.53658 442.2736 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.8 3268.3 - 1.32E+06 - - - 4.3692 - 1.466 0.278 - 229.4 1 2 0 0.0039 8 0 0 0 4.81E+07 3.80E+07 - - - 2.2468 0.9736 230117_WJC_METTL3_WT_vs_EV_F07.16094.16094.2 3.95 12-Jun K.ILIEDWK[136.11].K "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A7I2V2T6|A0A7I2V2T6_HUMAN,tr|K7EPW7|K7EPW7_HUMAN" 4 923.5208 1.21 58195 16094 2 923.522828 462.7677 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 4.37 3268.5 - 1.01E+06 - - - 2.2295 - 1.217 0.038 - 87.4 1 2 0 0.0021 7 0 0 0 5.98E+07 4.93E+07 - - - -0.0567 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.16098.16098.2 0.000261 16-Aug K.VLPVGVLYK[136.11].V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 994.6307 0.56 58196 16098 2 994.63038 498.3226 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3269 - 3.82E+06 - - - -0.2755 - 1.604 0.391 - 220.6 1 2 0 -0.0003 9 0 0 0 1.79E+08 3.21E+08 - - - 3.2958 0.9965 230117_WJC_METTL3_WT_vs_EV_F07.16099.16099.2 0.814 16-Nov R.TEIIILATR[166.11].T "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 10 1038.6313 1.87 58197 16099 2 1038.627883 520.3229 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.66 3269.1 - 1.41E+06 - - - -3.2572 - 2.117 0.381 - 598.2 1 2 0 -0.0034 9 0 0 0 8.69E+08 4.66E+08 - - - 4.0238 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.16104.16104.2 0.00149 18-Aug K.ILPEEITNLR[166.11].N sp|Q9H9A6|LRC40_HUMAN 1 1206.6848 0.92 58200 16104 2 1206.687998 604.3497 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3269.8 - 310775 - - - 2.685 - 1.655 0.386 - 213.7 1 2 0 0.0032 10 0 0 0 4.56E+07 4.94E+07 - - - 3.2972 0.9457 230117_WJC_METTL3_WT_vs_EV_F07.16105.16105.2 1.87 16-May K.VIIDTLITK[136.11].L sp|O15164|TIF1A_HUMAN 1 1022.6467 0.53 58201 16105 2 1022.647387 512.3306 Transcription intermediary factor 1-alpha OS=Homo sapiens OX=9606 GN=TRIM24 PE=1 SV=3 5.81 3269.9 - 168499 - - - 0.6737 - 1.059 0.093 - 37.9 12 2 0 0.0007 9 0 0 0 1.70E+07 3.19E+07 - - - -0.5885 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.16111.16111.2 0.465 14-Jul R.TLINELVK[136.11].G "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 7 936.5735 18.71 58205 16111 2 936.575042 469.294 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.66 3270.6 - 6.28E+06 - - - 1.6112 - 1.207 0.22 - 112.2 1 2 0 0.0015 8 0 0 0 1.60E+09 8.58E+07 - - - 1.2329 0.9397 230117_WJC_METTL3_WT_vs_EV_F07.16114.16114.2 0.74 14-Aug K.LIELLAGK.A sp|Q9NW08|RPC2_HUMAN 1 855.543 1.08 58208 16114 2 855.542393 428.7788 DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2 6 3270.8 - 1.19E+06 - - - -0.6557 - 1.131 0.048 - 127.9 1 2 0 -0.0006 8 0 0 0 1.57E+07 1.45E+07 - - - -0.2334 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.16115.16115.2 0.0144 14-Sep K.AVWLPAVK[136.11].A "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 890.5469 1.26 58209 16115 2 890.547774 446.2807 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.8 3270.9 - 964438 - - - 0.9545 - 1.536 0.303 - 286.6 1 2 0 0.0008 8 0 0 0 4.82E+07 3.82E+07 - - - 2.5731 0.9853 230117_WJC_METTL3_WT_vs_EV_F07.16116.16116.2 0.842 14-Jul K.LIELLAGK[136.11].A sp|Q9NW08|RPC2_HUMAN 1 863.5572 1.08 58210 16116 2 863.557279 432.7859 DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2 6 3271 - 763266 - - - 0.1448 - 1.392 0.07 - 100.3 2 2 0 0.0001 8 0 0 0 1.57E+07 1.45E+07 - - - 0.421 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.16117.16117.2 0.000355 20-Nov R.LVDAVLGAEIR[166.11].N "sp|Q9UBN7|HDAC6_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8Y758|A0A2R8Y758_HUMAN,tr|A0A2R8Y559|A0A2R8Y559_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 5 1164.6742 0.88 58211 16117 2 1164.678451 583.3444 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.37 3271.1 - 601182 - - - 3.656 - 2.035 0.352 - 176 1 2 0 0.0043 11 0 0 0 2.81E+07 3.20E+07 - - - 3.5616 0.9938 230117_WJC_METTL3_WT_vs_EV_F07.16121.16121.2 0.148 16-Jul K.IYPVGYFTK.E "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 1086.575 5.5 58213 16121 2 1086.57521 544.2948 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.5 3271.6 - 933117 - - - 0.2089 - 1.194 0.199 - 123.4 1 2 0 0.0002 9 0 0 0 1.02E+08 1.86E+07 - - - 1.0237 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.16122.16122.2 0.0396 20-Jun K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.12 58214 16122 2 1235.761208 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3271.6 - 507078 - - - 0.8497 - 1.635 0.23 - 128.3 1 2 0 0.001 11 0 0 0 3.43E+08 3.07E+08 - - - 2.0695 0.9956 230117_WJC_METTL3_WT_vs_EV_F07.16124.16124.2 0.418 20-Aug K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.12 58216 16124 2 1245.773404 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3271.8 - 590259 - - - 3.9943 - 1.491 0.274 - 127 1 2 0 0.005 11 0 0 0 3.45E+08 3.08E+08 - - - 2.1438 0.9965 230117_WJC_METTL3_WT_vs_EV_F07.16125.16125.2 0.472 14-Jun R.LLGWIQNK[136.11].L "sp|O75369|FLNB_HUMAN,sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN,tr|F8WE98|F8WE98_HUMAN" 11 978.5742 2.05 58217 16125 2 978.57514 490.2944 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 8.75 3271.9 - 394551 - - - 0.9585 - 1.11 0.26 - 69 1 2 0 0.0009 8 0 0 0 6.03E+07 2.94E+07 - - - 1.2758 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.16130.16130.2 8.32E-06 16-Jul K.VIVPNMEFR.A sp|P55060|XPO2_HUMAN 1 1103.5798 1.28 58219 16130 2 1103.581338 552.7972 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.97 3272.5 - 799309 - - - 1.438 - 1.722 0.485 - 171.1 1 2 0 0.0016 9 0 0 0 1.21E+08 9.43E+07 - - - 4.195 1 230117_WJC_METTL3_WT_vs_EV_F07.16132.16132.2 2.20E-06 20-Oct R.LVDAVLGAEIR.N "sp|Q9UBN7|HDAC6_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8Y758|A0A2R8Y758_HUMAN,tr|A0A2R8Y559|A0A2R8Y559_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 5 1154.6659 0.88 58221 16132 2 1154.666859 578.3402 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.37 3272.6 - 467704 - - - 0.8106 - 2.236 0.525 - 325.2 1 2 0 0.0009 11 0 0 0 2.81E+07 3.21E+07 - - - 5.0952 0.9957 230117_WJC_METTL3_WT_vs_EV_F07.16139.16139.2 0.184 18-May R.ILIAK[136.11]PIMFR[166.11].G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1218.7641 1.17 58226 16139 2 1218.764169 610.3893 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3273.5 - 639114 - - - 0.023 - 1.312 0.232 - 72.5 2 2 0 0 10 0 0 0 7.19E+06 6.14E+06 - - - 1.3781 0.9949 230117_WJC_METTL3_WT_vs_EV_F07.16144.16144.2 0.155 14-Jul K.LLFVPC[160.03]SR.V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 990.5321 0.8 58229 16144 2 990.53286 496.2733 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.25 3274.1 - 656052 - - - 0.7955 - 1.341 0.146 - 109.6 1 2 0 0.0008 8 0 0 0 5.43E+07 6.75E+07 - - - 1.004 1 230117_WJC_METTL3_WT_vs_EV_F07.16149.16149.2 2.04E-06 18-Nov K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 8.55 58232 16149 2 1149.583643 575.7982 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3274.7 - 618769 - - - 1.5519 - 2.217 0.502 - 464.5 1 2 0 0.0018 10 0 0 0 9.46E+08 1.11E+08 - - - 4.9705 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.16154.16154.2 0.0181 24-Sep K.LGPGAGAGFGVLR.R "sp|Q9BUL5|PHF23_HUMAN,tr|I3L1N0|I3L1N0_HUMAN,tr|I3L410|I3L410_HUMAN,tr|I3L4Q4|I3L4Q4_HUMAN" 4 1170.6509 4.93 58235 16154 2 1170.655627 586.3327 PHD finger protein 23 OS=Homo sapiens OX=9606 GN=PHF23 PE=1 SV=1 9.75 3275.4 - 456287 - - - 4.002 - 1.857 0.306 - 162.9 1 2 0 0.0047 13 0 0 0 1.90E+07 3.85E+06 - - - 2.8882 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.16156.16156.2 0.00869 18-Sep R.TVPLLLAESK[136.11].F sp|Q709C8|VP13C_HUMAN 1 1077.6525 0.83 58237 16156 2 1077.655307 539.8335 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 5.66 3275.6 - 535781 - - - 2.5945 - 1.58 0.284 - 212.6 1 2 0 0.0028 10 0 0 0 1.07E+07 1.29E+07 - - - 2.4146 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.16161.16161.2 0.0574 12-Jun R.EEYLLLR.L "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 934.5124 1.14 58240 16161 2 934.514237 468.2635 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.53 3276.3 - 722520 - - - 1.9839 - 1.336 0.285 - 134.6 1 2 0 0.0019 7 0 0 0 7.02E+07 6.17E+07 - - - 2.0633 1 230117_WJC_METTL3_WT_vs_EV_F07.16167.16167.2 0.0013 18-Nov K.FAEAFEAIPR[166.11].A sp|P50990|TCPQ_HUMAN 1 1159.5901 8.57 58244 16167 2 1159.59291 580.8023 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3277.1 - 329230 - - - 2.3983 - 2.346 0.494 - 404.1 1 2 0 0.0028 10 0 0 0 9.45E+08 1.10E+08 - - - 5.069 0.8858 230117_WJC_METTL3_WT_vs_EV_F07.16171.16171.2 0.444 12-Sep A.IIAELLR.L "sp|Q12768|WASC5_HUMAN,sp|P16444|DPEP1_HUMAN,sp|Q9Y4D8|HECD4_HUMAN,sp|Q7L2E3|DHX30_HUMAN,sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HJX8|A0A804HJX8_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A494C150|A0A494C150_HUMAN,tr|A0A804HJG8|A0A804HJG8_HUMAN,tr|F8VWT9|F8VWT9_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|H7BXY3|H7BXY3_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|J3KPF0|J3KPF0_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 24 826.5276 1.05 58247 16171 2 826.528345 414.2711 WASH complex subunit 5 OS=Homo sapiens OX=9606 GN=WASHC5 PE=1 SV=1 6 3277.5 - 5.63E+06 - - - 0.8542 - 1.609 0.191 - 261.3 1 1 0 0.0007 7 0 0 0 2.15E+08 2.05E+08 - - - 1.9585 0.9951 230117_WJC_METTL3_WT_vs_EV_F07.16188.16188.2 0.378 12-Jul K.VFGIQLK.E "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN" 3 803.4905 9.28 58259 16188 2 803.49225 402.7525 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 8.72 3279.6 - 2.15E+06 - - - 2.1469 - 1.254 0.184 - 141.1 1 2 0 0.0017 7 0 0 0 5.19E+07 5.59E+06 - - - 1.1166 0.9963 230117_WJC_METTL3_WT_vs_EV_F07.16193.16193.2 0.576 16-Aug R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 0.74 58263 16193 2 960.612244 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3280.3 - 4.48E+06 - - - 2.4214 - 1.219 0.245 - 184.9 1 2 0 0.0023 9 0 0 0 1.65E+10 2.22E+10 - - - 1.4228 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.16194.16194.2 9.96E-05 16-Aug K.VIVPNMEFR[166.11].A sp|P55060|XPO2_HUMAN 1 1113.588 1.3 58264 16194 2 1113.591459 557.8013 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.97 3280.3 - 2.37E+06 - - - 3.0873 - 1.647 0.443 - 229.8 1 2 0 0.0034 9 0 0 0 1.20E+08 9.22E+07 - - - 3.7554 0.9258 230117_WJC_METTL3_WT_vs_EV_F07.16207.16207.2 4.68 12-May R.LIEIEKR.E sp|Q96MT7|CFA44_HUMAN 1 899.544 9.82 58273 16207 2 899.544911 450.7793 Cilia- and flagella-associated protein 44 OS=Homo sapiens OX=9606 GN=CFAP44 PE=1 SV=2 6.14 3281.9 - 404987 - - - 0.9938 - 1.131 0 - 67.5 4 2 0 0.0009 7 0 0 0 7.47E+06 7.61E+05 - - - -0.8382 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.16211.16211.2 0.0183 14-Jul K.ELPTVVFR[166.11].A sp|Q9BVP2|GNL3_HUMAN 1 969.5523 0.85 58276 16211 2 969.553586 485.7834 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 6.1 3282.2 - 4.49E+06 - - - 1.3398 - 1.357 0.287 - 237.1 1 2 0 0.0013 8 0 0 0 1.06E+08 1.24E+08 - - - 2.0811 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.16214.16214.3 0.282 13/36 K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 14.17 58278 16214 3 1149.582829 384.2012 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3282.5 - 686844 - - - 0.8438 - 1.751 0.33 - 305.2 1 2 0 0.001 10 0 0 0 1.17E+07 8.24E+05 - - - 3.8549 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.16226.16226.2 0.101 16-Jun R.LGSLVDEFK.E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1006.5335 0.11 58286 16226 2 1006.535301 504.274 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3284 - 3.66E+06 - - - 1.7774 - 1.579 0.247 - 96.2 1 2 0 0.0018 9 0 0 0 1.52E+08 1.34E+09 - - - 2.1863 0.999 230117_WJC_METTL3_WT_vs_EV_F07.16228.16228.2 0.351 20-Sep K.LLLIGDSGVGK.T "sp|P61006|RAB8A_HUMAN,sp|P51153|RAB13_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P59190|RAB15_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YL94|H0YL94_HUMAN,tr|A0A2R8YDI9|A0A2R8YDI9_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|G3V196|G3V196_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H0YLJ8|H0YLJ8_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN,tr|F5H157|F5H157_HUMAN" 19 1070.6336 1.43 58288 16228 2 1070.636277 536.3241 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.84 3284.1 - 7.72E+06 - - - 2.5377 - 1.564 0.338 - 201.8 1 2 0 0.0027 11 0 0 0 2.59E+08 1.81E+08 - - - 2.7465 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.16234.16234.2 0.152 16-Sep K.LTLLQVASR.Q sp|O95239|KIF4A_HUMAN 1 999.6077 2.12 58292 16234 2 999.608905 500.8111 Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3 9.75 3284.8 - 709047 - - - 1.2255 - 1.972 0.274 - 250 1 2 0 0.0012 9 0 0 0 2.28E+07 1.07E+07 - - - 3.0289 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.16240.16240.2 0.332 12-Sep K.IIAALFK[136.11].A "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 782.5146 2.01 58295 16240 2 782.515047 392.2646 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3285.6 - 940195 - - - 0.6211 - 1.783 0.14 - 200.5 1 2 0 0.0005 7 0 0 0 3.08E+07 1.53E+07 - - - 1.9073 0.9621 230117_WJC_METTL3_WT_vs_EV_F07.16241.16241.2 0.000108 16-Sep K.YEDGIALLR.N "sp|Q9UJX3|APC7_HUMAN,tr|H0YIW2|H0YIW2_HUMAN" 2 1048.5553 1.18 58296 16241 2 1048.548334 525.2849 Anaphase-promoting complex subunit 7 OS=Homo sapiens OX=9606 GN=ANAPC7 PE=1 SV=4 4.37 3285.8 - 275428 - - - -6.653 - 1.73 0.385 - 217.1 1 2 0 -0.007 9 0 0 0 8.75E+06 7.44E+06 - - - 3.4682 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.16242.16242.2 0.0012 12-Aug K.FGDFVLK.S "sp|P11172|UMPS_HUMAN,tr|F2Z303|F2Z303_HUMAN,tr|F2Z3P2|F2Z3P2_HUMAN,tr|F8WDG4|F8WDG4_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 5 824.4432 2.05 58297 16242 2 824.443797 413.2289 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 5.84 3285.8 - 2.47E+06 - - - 0.6756 - 1.322 0.381 - 172.4 1 2 0 0.0006 7 0 0 0 6.74E+07 3.29E+07 - - - 2.7394 0.9943 230117_WJC_METTL3_WT_vs_EV_F07.16243.16243.2 0.16 12-Jun K.FGDFVLK[136.11].S "sp|P11172|UMPS_HUMAN,tr|F2Z303|F2Z303_HUMAN,tr|F2Z3P2|F2Z3P2_HUMAN,tr|F8WDG4|F8WDG4_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 5 832.4574 2.07 58298 16243 2 832.457594 417.236 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 5.84 3285.9 - 1.08E+06 - - - 0.185 - 1.28 0.173 - 85.3 1 2 0 0.0002 7 0 0 0 6.74E+07 3.25E+07 - - - 1.1009 0.9499 230117_WJC_METTL3_WT_vs_EV_F07.16247.16247.2 1.9 14-May R.LISLPLSR[166.11].L "sp|Q9NRG0|CHRC1_HUMAN,tr|E5RGS9|E5RGS9_HUMAN" 2 907.573 1.91 58300 16247 2 907.574051 454.7938 Chromatin accessibility complex protein 1 OS=Homo sapiens OX=9606 GN=CHRAC1 PE=1 SV=1 9.75 3286.3 - 523695 - - - 1.1327 - 1.044 0.032 - 59.1 1 2 0 0.001 8 0 0 0 5.39E+07 2.82E+07 - - - -0.5931 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.16248.16248.2 0.124 14-Sep R.LLAMAVIR.K sp|Q96EK4|THA11_HUMAN 1 885.547 0.2 58301 16248 2 885.547759 443.7808 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 9.75 3286.4 - 584621 - - - 0.8639 - 1.48 0.286 - 237.9 1 2 0 0.0008 8 0 0 0 1.04E+07 5.27E+07 - - - 2.3355 0.9928 230117_WJC_METTL3_WT_vs_EV_F07.16249.16249.2 0.108 14-Sep R.LEEIPLIK[136.11].S sp|Q14152|EIF3A_HUMAN 1 961.5939 0.92 58302 16249 2 961.591919 481.8042 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 3286.5 - 1.18E+06 - - - -2.0955 - 1.685 0.202 - 180.3 1 2 0 -0.002 8 0 0 0 6.51E+07 7.08E+07 - - - 2.106 0.9946 230117_WJC_METTL3_WT_vs_EV_F07.16250.16250.2 0.154 12-Jul K.YLWNNIK[136.11].R "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 957.5164 1.44 58303 16250 2 957.51815 479.7655 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 8.59 3286.5 - 669352 - - - 1.8778 - 1.297 0.149 - 102.2 1 2 0 0.0018 7 0 0 0 2.24E+07 1.56E+07 - - - 0.9649 0.9487 230117_WJC_METTL3_WT_vs_EV_F07.16251.16251.2 0.0504 14-Aug R.PLELSDFR.M "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 975.5025 1.66 58304 16251 2 975.502966 488.7585 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.37 3286.6 - 460207 - - - 0.4305 - 1.776 0.309 - 242.7 1 1 0 0.0004 8 0 0 0 3.72E+07 2.24E+07 - - - 3.0554 0.8571 230117_WJC_METTL3_WT_vs_EV_F07.16252.16252.2 0.0406 18-Jun L.AENAAVDVVR[166.11].A "sp|Q0VG06|FP100_HUMAN,tr|E7EVV8|E7EVV8_HUMAN" 2 1052.549 0.71 58305 16252 2 1052.549071 527.2818 Fanconi anemia core complex-associated protein 100 OS=Homo sapiens OX=9606 GN=FAAP100 PE=1 SV=3 4.37 3286.7 - 207847 - - - 0.0741 - 1.519 0.242 - 84.3 1 1 0 0.0001 10 0 0 0 6.94E+06 9.83E+06 - - - 1.9953 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.16254.16254.2 0.00416 18-Sep K.ILVEEMAPLK.G "sp|Q16670|ZSC26_HUMAN,tr|A0A087WXM4|A0A087WXM4_HUMAN,tr|A0A024RCN4|A0A024RCN4_HUMAN,tr|A0A087X2F1|A0A087X2F1_HUMAN" 4 1141.6417 999 58307 16254 2 1141.642329 571.8281 Zinc finger and SCAN domain-containing protein 26 OS=Homo sapiens OX=9606 GN=ZSCAN26 PE=1 SV=2 4.53 3287 - 168308 - - - 0.5667 - 1.806 0.431 - 194.1 1 2 0 0.0006 10 0 0 0 2.78E+06 0.00E+00 - - - 3.8741 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.16257.16257.2 0.49 14-Jun K.LFIGNLPR.E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 928.5494 2.14 58309 16257 2 928.550511 465.282 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3287.4 - 1.92E+08 - - - 1.1566 - 1.333 0.214 - 143.3 1 2 0 0.0011 8 0 0 0 2.56E+09 1.20E+09 - - - 1.4881 0.9024 230117_WJC_METTL3_WT_vs_EV_F07.16259.16259.2 0.811 14-Jun R.LEEIPLIK.S sp|Q14152|EIF3A_HUMAN 1 953.5797 0.94 58311 16259 2 953.577186 477.7971 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 3287.4 - 3.54E+06 - - - -2.672 - 1.091 0.13 - 72.6 1 2 0 -0.0025 8 0 0 0 6.66E+07 7.08E+07 - - - 0.2631 0.9947 230117_WJC_METTL3_WT_vs_EV_F07.16260.16260.2 3.47 14-Oct K.GGLGLILK.R "sp|O75832|PSD10_HUMAN,tr|B1AJY5|B1AJY5_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 3 769.5062 1.59 58312 16260 2 769.506565 385.7604 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 8.75 3287.6 - 1.76E+06 - - - 0.5068 - 1.469 0.115 - 243.8 1 2 0 0.0004 8 0 0 0 5.61E+07 3.52E+07 - - - 1.0501 0.8604 230117_WJC_METTL3_WT_vs_EV_F07.16262.16262.2 0.206 14-Jul R.PLELSDFR[166.11].M "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 985.5108 1.63 58314 16262 2 985.511608 493.7627 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.37 3287.8 - 1.21E+06 - - - 0.8036 - 1.466 0.212 - 189.2 1 1 0 0.0008 8 0 0 0 3.74E+07 2.30E+07 - - - 1.7603 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.16264.16264.2 0.00227 14-Jul R.GFVLYPVK.Y sp|P62487|RPB7_HUMAN 1 921.5324 0.01 58316 16264 2 921.534322 461.7735 DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1 8.59 3288.1 - 710682 - - - 2.0965 - 1.244 0.322 - 135.8 1 2 0 0.0019 8 0 0 0 1.69E+07 1.29E+09 - - - 2.0772 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.16268.16268.2 0.325 12-Jul K.IIAALFK.A "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 774.5004 1.93 58319 16268 2 774.500591 388.2575 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3288.5 - 1.21E+06 - - - 0.297 - 1.604 0.154 - 98.9 1 2 0 0.0002 7 0 0 0 2.96E+07 1.53E+07 - - - 1.6755 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.16273.16273.2 1.02 12-Jul R.LSAIFLR.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 818.5014 1.56 58323 16273 2 818.502241 410.258 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3289.1 - 1.42E+06 - - - 0.9982 - 1.675 0.089 - 155.9 1 2 0 0.0008 7 0 0 0 3.76E+07 2.42E+07 - - - 1.3325 1 230117_WJC_METTL3_WT_vs_EV_F07.16274.16274.2 2.81E-07 20-Dec K.NSLESYAFNMK.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1302.5914 19.81 58324 16274 2 1302.590951 652.303 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6 3289.3 - 755470 - - - -0.3739 - 2.755 0.575 - 770.3 1 2 0 -0.0005 11 0 0 0 1.01E+07 5.08E+05 - - - 6.0293 0.999 230117_WJC_METTL3_WT_vs_EV_F07.16275.16275.3 0.0338 Aug-36 K.DR[166.11]PFFPGLVK[136.11].Y "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN" 5 1192.6723 1.28 58325 16275 3 1192.673897 398.5647 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 8.75 3289.4 - 682290 - - - 1.2979 - 1.413 0.326 - 71.2 1 2 0 0.0015 10 0 0 0 3.98E+06 3.11E+06 - - - 3.1838 0.975 230117_WJC_METTL3_WT_vs_EV_F07.16277.16277.2 0.178 12-Jul R.NLVLLVR[166.11].E sp|Q9H2W6|RM46_HUMAN 1 835.5519 1.13 58327 16277 2 835.554651 418.7832 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 9.75 3289.6 - 512994 - - - 3.3008 - 1.584 0.002 - 159.4 2 2 0 0.0028 7 0 0 0 4.49E+07 3.97E+07 - - - 0.3778 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.16279.16279.2 0.000101 18-Sep K.AMTILLEEAK.A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1117.6053 2.27 58329 16279 2 1117.603753 559.8099 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3289.9 - 209673 - - - -1.3815 - 1.974 0.311 - 271.2 1 2 0 -0.0015 10 0 0 0 3.47E+07 1.53E+07 - - - 3.2358 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.16283.16283.2 1.72 12-Sep R.LSAIFLR[166.11].L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 828.5097 1.28 58331 16283 2 828.510575 415.2621 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3290.4 - 1.57E+06 - - - 1.0634 - 1.817 0.116 - 245.3 1 2 0 0.0009 7 0 0 0 3.81E+07 2.97E+07 - - - 1.7897 0.9902 230117_WJC_METTL3_WT_vs_EV_F07.16285.16285.2 0.101 12-Jun R.EYFYGFR.G "sp|Q92989|CLP1_HUMAN,tr|E9PL17|E9PL17_HUMAN" 2 980.4392 2.59 58333 16285 2 980.441604 491.2269 Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1 6.1 3290.7 - 682576 - - - 2.4336 - 1.093 0.185 - 137.3 1 2 0 0.0024 7 0 0 0 4.43E+06 1.71E+06 - - - 0.6884 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.16287.16287.2 0.0287 18-Oct K.AMTILLEEAK[136.11].A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1125.6195 2.28 58335 16287 2 1125.620352 563.817 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3291 - 342341 - - - 0.7596 - 2.085 0.366 - 372 1 2 0 0.0009 10 0 0 0 3.47E+07 1.52E+07 - - - 3.795 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.16288.16288.2 0.00504 16-Sep R.FDDPLLGPR[166.11].R "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 8 1038.5374 0.92 58336 16288 2 1038.538636 520.276 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.21 3291.1 - 240856 - - - 1.2238 - 1.72 0.416 - 207.3 1 2 0 0.0013 9 0 0 0 8.88E+07 9.62E+07 - - - 3.6822 1 230117_WJC_METTL3_WT_vs_EV_F07.16292.16292.2 6.11E-05 18-Nov K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 335.86 58338 16292 2 1146.630816 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3291.5 - 6.46E+06 - - - 2.0416 - 2.136 0.467 - 355.7 1 2 0 0.0023 10 0 0 0 4.63E+09 1.38E+07 - - - 4.6079 0.9613 230117_WJC_METTL3_WT_vs_EV_F07.16294.16294.2 7.65 12-Jun R.LIFDNLK[136.11].K "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P54707|AT12A_HUMAN,sp|P20648|ATP4A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 11 869.5102 1.32 58340 16294 2 869.512084 435.7624 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.84 3291.7 - 3.08E+06 - - - 2.1621 - 1.037 0.07 - 85.8 1 2 0 0.0019 7 0 0 0 5.53E+07 4.20E+07 - - - -0.3275 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.16298.16298.2 0.00222 20-Oct K.C[160.03]ILVASPGFVR.E sp|Q9BRX2|PELO_HUMAN 1 1217.6591 3.57 58344 16298 2 1217.663492 609.8368 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 8.25 3292.1 - 821620 - - - 3.6365 - 2.075 0.249 - 269.8 1 2 0 0.0044 11 0 0 0 1.41E+07 3.94E+06 - - - 2.8534 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.16299.16299.2 0.0107 20-Sep K.C[160.03]ILVASPGFVR[166.11].E sp|Q9BRX2|PELO_HUMAN 1 1227.6673 3.57 58345 16299 2 1227.669857 614.8409 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 8.25 3292.3 - 383155 - - - 2.0551 - 1.657 0.268 - 236.1 1 2 0 0.0025 11 0 0 0 1.41E+07 3.94E+06 - - - 2.3858 0.9949 230117_WJC_METTL3_WT_vs_EV_F07.16306.16306.2 0.619 12-Aug R.NLVLLVR.E sp|Q9H2W6|RM46_HUMAN 1 825.5436 1.12 58350 16306 2 825.54567 413.7791 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 9.75 3293.1 - 1.18E+06 - - - 2.4796 - 1.542 0.107 - 265.7 1 2 0 0.002 7 0 0 0 4.45E+07 3.97E+07 - - - 1.2029 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.16310.16310.2 0.0028 16-Sep K.VVDVLDSIK[136.11].T sp|P00918|CAH2_HUMAN 1 994.579 0.86 58354 16310 2 994.581102 498.2968 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.21 3293.4 - 509510 - - - 2.1014 - 1.919 0.344 - 232.7 1 2 0 0.0021 9 0 0 0 2.69E+07 3.12E+07 - - - 3.4668 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.16316.16316.2 0.423 12-Jun K.ILPDILK.K "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 810.5215 1.77 58358 16316 2 810.522525 406.268 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 3294.1 - 1.45E+06 - - - 1.2757 - 1.18 0.2 - 92.4 1 2 0 0.001 7 0 0 0 1.16E+08 6.57E+07 - - - 1.0423 0.907 230117_WJC_METTL3_WT_vs_EV_F07.16317.16317.2 0.361 14-Aug F.AFLWAGGR.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A1W2PNG3|A0A1W2PNG3_HUMAN" 12 876.4606 1.25 58359 16317 2 876.461828 439.2376 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.79 3294.2 - 2.02E+06 - - - 1.376 - 1.545 0.24 - 251.3 1 1 0 0.0012 8 0 0 0 2.31E+09 1.85E+09 - - - 2.1253 0.9949 230117_WJC_METTL3_WT_vs_EV_F07.16318.16318.2 0.828 14-May M.VLLTMIAR.V sp|O75396|SC22B_HUMAN 1 915.5576 0.46 58360 16318 2 915.558999 458.7861 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 9.72 3294.2 - 977217 - - - 1.5728 - 1.245 0.172 - 84 1 2 0 0.0014 8 0 0 0 8.48E+07 1.85E+08 - - - 0.9718 0.9952 230117_WJC_METTL3_WT_vs_EV_F07.16319.16319.2 0.882 16-Aug K.VVDVLDSIK.T sp|P00918|CAH2_HUMAN 1 986.5648 0.87 58361 16319 2 986.565623 494.2897 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.21 3294.3 - 907896 - - - 0.822 - 1.386 0.144 - 135.2 1 2 0 0.0008 9 0 0 0 2.69E+07 3.10E+07 - - - 1.0487 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.16320.16320.2 0.00592 18-Oct K.LLADELISPK[136.11].D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1105.6474 1.13 58362 16320 2 1105.648514 553.831 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3294.3 - 895862 - - - 0.984 - 2.067 0.438 - 212.6 1 2 0 0.0011 10 0 0 0 8.20E+07 7.27E+07 - - - 4.3025 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.16327.16327.2 0.000515 16-Sep K.AFIGFEGVK.G sp|P15924|DESP_HUMAN 1 966.5175 2.54 58367 16327 2 966.516277 484.266 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.05 3295.2 - 803997 - - - -1.2323 - 1.625 0.41 - 239.7 1 2 0 -0.0012 9 0 0 0 7.43E+07 2.92E+07 - - - 3.4735 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.16329.16329.2 0.018 16-Jul R.WLNYGGVIK.N "sp|P49642|PRI1_HUMAN,tr|F8VSB2|F8VSB2_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN" 3 1048.5706 0.36 58369 16329 2 1048.574935 525.2926 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 8.59 3295.3 - 182176 - - - 4.1666 - 1.539 0.339 - 133.3 1 2 0 0.0044 9 0 0 0 2.32E+06 6.36E+06 - - - 2.7908 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.16332.16332.2 0.00408 16-Aug R.IVLNGIDLK.A sp|O15294|OGT1_HUMAN 1 983.6015 1.94 58370 16332 2 983.603483 492.808 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 5.84 3295.7 - 1.76E+06 - - - 1.9835 - 1.693 0.195 - 127.9 1 2 0 0.002 9 0 0 0 3.08E+07 1.59E+07 - - - 2.0039 0.9957 230117_WJC_METTL3_WT_vs_EV_F07.16333.16333.2 0.00175 16-Jun R.IVLNGIDLK[136.11].A sp|O15294|OGT1_HUMAN 1 991.6157 1.94 58371 16333 2 991.615281 496.8151 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 5.84 3295.9 - 1.08E+06 - - - -0.4548 - 1.556 0.176 - 77.2 1 2 0 -0.0005 9 0 0 0 3.08E+07 1.59E+07 - - - 1.6199 0.997 230117_WJC_METTL3_WT_vs_EV_F07.16334.16334.2 0.899 12-Jul K.ILPDILK[136.11].K "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 818.5357 2.43 58372 16334 2 818.536712 410.2751 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 3295.9 - 1.53E+06 - - - 1.2473 - 1.46 0.153 - 107.5 1 2 0 0.001 7 0 0 0 1.11E+08 4.57E+07 - - - 1.3698 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.16336.16336.2 0.00911 18-Aug R.LTPLQLEIQR[166.11].V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1219.7164 1.19 58374 16336 2 1219.718068 610.8655 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 3296.1 - 904668 - - - 1.3741 - 1.646 0.314 - 264.8 1 2 0 0.0017 10 0 0 0 5.22E+07 4.40E+07 - - - 2.7507 1 230117_WJC_METTL3_WT_vs_EV_F07.16339.16339.2 0.000622 20-Nov K.LLDSITVPVAR[166.11].A sp|O00203|AP3B1_HUMAN 1 1192.7055 1.26 58377 16339 2 1192.70521 597.36 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3296.4 - 160030 - - - -0.2373 - 2.186 0.47 - 310.7 1 2 0 -0.0003 11 0 0 0 3.12E+07 2.48E+07 - - - 4.628 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.16342.16342.2 0.0179 18-Nov K.LLADELISPK.D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1097.6332 1.13 58378 16342 2 1097.635366 549.8239 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3296.8 - 3.43E+06 - - - 1.9496 - 2.16 0.317 - 322.9 1 2 0 0.0021 10 0 0 0 8.22E+07 7.29E+07 - - - 3.5313 0.946 230117_WJC_METTL3_WT_vs_EV_F07.16343.16343.2 5.62 16-May R.LMGSILGVR[166.11].R "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 954.556 1.17 58379 16343 2 954.557471 478.2853 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 9.75 3296.9 - 3.06E+06 - - - 1.5494 - 1.155 0.029 - 41.3 5 2 0 0.0015 9 0 0 0 5.00E+07 4.28E+07 - - - -0.6406 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.16345.16345.2 0.0885 14-Aug R.LLNTFLER.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 8 1004.5655 1.43 58381 16345 2 1004.565149 503.29 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3297 - 2.82E+06 - - - -0.3305 - 1.778 0.275 - 177.8 1 2 0 -0.0003 8 0 0 0 1.85E+08 1.29E+08 - - - 2.8077 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.16346.16346.2 0.125 12-Jul K.MFEFYER.V "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 13 1020.4375 1.93 58382 16346 2 1020.439456 511.226 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3297 - 1.65E+06 - - - 1.9139 - 1.49 0.269 - 231.3 1 2 0 0.002 7 0 0 0 2.50E+07 1.30E+07 - - - 2.2908 0.9639 230117_WJC_METTL3_WT_vs_EV_F07.16351.16351.2 12.7 12-Jun K.AFIVELR[166.11].Q sp|O43318|M3K7_HUMAN 1 856.5046 0.9 58385 16351 2 856.505011 429.2596 Mitogen-activated protein kinase kinase kinase 7 OS=Homo sapiens OX=9606 GN=MAP3K7 PE=1 SV=1 6.05 3297.6 - 1.45E+06 - - - 0.4693 - 1.124 0.042 - 126.9 1 2 0 0.0004 7 0 0 0 9.24E+06 1.03E+07 - - - -0.2785 0.9944 230117_WJC_METTL3_WT_vs_EV_F07.16354.16354.2 0.00771 14-Jul K.FYSFALDK[136.11].T sp|Q96T58|MINT_HUMAN 1 997.5 0.95 58388 16354 2 997.503343 499.7573 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.83 3297.8 - 1.49E+06 - - - 3.3173 - 1.368 0.208 - 145 1 2 0 0.0033 8 0 0 0 4.33E+07 4.54E+07 - - - 1.5213 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.16358.16358.2 0.237 12-Jul R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 12.38 58390 16358 2 806.392476 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 3298.3 - 3.10E+06 - - - 0.2592 - 1.455 0.257 - 191.9 1 2 0 0.0002 7 0 0 0 6.92E+07 5.59E+06 - - - 2.1274 0.9201 230117_WJC_METTL3_WT_vs_EV_F07.16359.16359.2 0.000648 14-Aug K.FYSFALDK.T sp|Q96T58|MINT_HUMAN 1 989.4858 0.88 58391 16359 2 990.489415 495.7502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.83 3298.4 - 1.19E+06 - - - 1014.2449 - 1.343 0.423 - 141 1 2 0 1.0036 8 0 0 0 3.96E+07 4.51E+07 - - - 2.7396 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.16360.16360.2 0.00547 18-Sep R.LTPLQLEIQR.V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1209.7081 1.19 58392 16360 2 1209.7083 605.8613 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 3298.5 - 2.14E+06 - - - 0.1471 - 1.719 0.328 - 433.4 1 2 0 0.0002 10 0 0 0 5.22E+07 4.40E+07 - - - 2.9757 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.16364.16364.2 0.00679 20-Oct K.LLDSITVPVAR.A sp|O00203|AP3B1_HUMAN 1 1182.6972 1.26 58394 16364 2 1182.696177 592.3559 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3299 - 1.42E+06 - - - -0.8844 - 2.026 0.394 - 263.3 1 2 0 -0.001 11 0 0 0 3.12E+07 2.48E+07 - - - 3.8608 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.16365.16365.2 0.448 18-Aug K.IPVSGPFLVK.T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1055.6379 1.31 58395 16365 2 1055.638316 528.8262 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3299.1 - 282761 - - - 0.377 - 1.504 0.221 - 90.1 2 2 0 0.0004 10 0 0 0 2.45E+08 1.87E+08 - - - 1.6779 0.8986 230117_WJC_METTL3_WT_vs_EV_F07.16370.16370.2 1.02 14-Sep F.AFLWAGGR[166.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A1W2PNG3|A0A1W2PNG3_HUMAN" 12 886.4689 1.25 58398 16370 2 886.469059 444.2417 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.79 3299.7 - 5.79E+07 - - - 0.1884 - 1.696 0.247 - 398.3 2 1 0 0.0002 8 0 0 0 2.31E+09 1.85E+09 - - - 2.3241 0.8622 230117_WJC_METTL3_WT_vs_EV_F07.16376.16376.2 0.00135 22-Oct R.GLLQDDAHPTLV.T "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1277.6616 - 58402 16376 2 1277.659699 639.8381 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3300.5 - 539501 - - - -1.4613 - 1.648 0.37 - 157.8 1 1 0 -0.0019 12 0 0 0 - - - - - 3.0877 0.9903 230117_WJC_METTL3_WT_vs_EV_F07.16377.16377.2 0.0554 12-Jul K.LMVIFSK.V "sp|Q9BRK5|CAB45_HUMAN,tr|A0A5F9UJX7|A0A5F9UJX7_HUMAN,tr|A0A5F9UP49|A0A5F9UP49_HUMAN,tr|G3V1E2|G3V1E2_HUMAN,tr|H0Y3T6|H0Y3T6_HUMAN" 5 836.483 0.23 58403 16377 2 836.482288 419.2488 45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1 8.75 3300.6 - 867884 - - - -0.8476 - 1.494 0.132 - 144.5 2 2 0 -0.0007 7 0 0 0 2.80E+07 1.23E+08 - - - 1.1533 0.9943 230117_WJC_METTL3_WT_vs_EV_F07.16378.16378.2 3.73 12-Jun R.ALVELLR.E "sp|Q92974|ARHG2_HUMAN,tr|A0A5F9ZI21|A0A5F9ZI21_HUMAN,tr|V9GYM8|V9GYM8_HUMAN" 3 812.512 1.58 58404 16378 2 812.512057 407.2633 Rho guanine nucleotide exchange factor 2 OS=Homo sapiens OX=9606 GN=ARHGEF2 PE=1 SV=4 6.05 3300.6 - 5.06E+06 - - - 0.0837 - 1.202 0.204 - 120.3 1 2 0 0.0001 7 0 0 0 4.85E+07 3.06E+07 - - - 1.1307 1 230117_WJC_METTL3_WT_vs_EV_F07.16380.16380.2 0.000978 14/22 K.LGALTAEEIALK.M sp|Q13601|KRR1_HUMAN 1 1227.7075 1.25 58406 16380 2 1227.706158 614.861 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3300.8 - 759367 - - - -1.0556 - 2.544 0.439 - 634.6 1 2 0 -0.0013 12 0 0 0 1.29E+08 1.03E+08 - - - 4.7399 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.16393.16393.2 0.547 20-Oct K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 0.87 58414 16393 2 1245.768248 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3302.3 - 1.83E+06 - - - -0.1445 - 1.721 0.276 - 250.1 1 2 0 -0.0002 11 0 0 0 9.44E+07 1.08E+08 - - - 2.5482 0.9949 230117_WJC_METTL3_WT_vs_EV_F07.16395.16395.2 0.108 18-Sep K.IPVSGPFLVK[136.11].T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1063.6521 1.31 58415 16395 2 1063.652277 532.8333 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3302.5 - 1.17E+06 - - - 0.1495 - 1.374 0.171 - 179.6 1 2 0 0.0002 10 0 0 0 2.45E+08 1.87E+08 - - - 1.1908 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.16397.16397.2 0.606 14-Sep R.LMGLEALK.S "sp|P48643|TCPE_HUMAN,tr|D6RIZ7|D6RIZ7_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0Y914|H0Y914_HUMAN" 4 873.4994 5.37 58416 16397 2 873.501106 437.757 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 3302.7 - 4.60E+07 - - - 1.9817 - 1.811 0.256 - 262.5 1 2 0 0.0017 8 0 0 0 2.53E+09 4.71E+08 - - - 2.7224 0.999 230117_WJC_METTL3_WT_vs_EV_F07.16398.16398.2 0.000513 18-Oct K.LGLTEDQFIR.T "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1190.6295 3.06 58417 16398 2 1190.628523 596.322 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.37 3302.9 - 576088 - - - -0.8525 - 1.801 0.384 - 223.1 1 2 0 -0.001 10 0 0 0 1.63E+07 5.35E+06 - - - 3.5191 0.998 230117_WJC_METTL3_WT_vs_EV_F07.16399.16399.2 0.0117 14-Jun K.STLFWGAR.Y "sp|Q96QA5|GSDMA_HUMAN,tr|J3KRG2|J3KRG2_HUMAN" 2 936.4818 1.32 58418 16399 2 936.481885 469.2482 Gasdermin-A OS=Homo sapiens OX=9606 GN=GSDMA PE=1 SV=4 9.47 3302.9 - 1.01E+06 - - - 0.1431 - 1.215 0.323 - 96.5 1 2 0 0.0001 8 0 0 0 1.55E+08 1.17E+08 - - - 2.014 0.8535 230117_WJC_METTL3_WT_vs_EV_F07.16402.16402.2 3.78 16-Jun R.VISEGMLWK[136.11].K "sp|Q9UKB1|FBW1B_HUMAN,tr|E5RGC1|E5RGC1_HUMAN" 2 1069.5722 0.72 58421 16402 2 1069.575185 535.7934 F-box\WD repeat-containing protein 11 OS=Homo sapiens OX=9606 GN=FBXW11 PE=1 SV=1 5.97 3303.3 - 386284 - - - 2.8348 - 0.848 0.058 - 64.8 1 2 0 0.003 9 0 0 0 7.76E+06 1.07E+07 - - - -1.0086 0.9947 230117_WJC_METTL3_WT_vs_EV_F07.16406.16406.2 2.97 12-Jun K.DVLLPLK.S sp|Q9Y385|UB2J1_HUMAN 1 796.5058 1.18 58423 16406 2 796.508086 399.2602 Ubiquitin-conjugating enzyme E2 J1 OS=Homo sapiens OX=9606 GN=UBE2J1 PE=1 SV=2 5.84 3303.8 - 229337 - - - 2.8186 - 1.331 0.185 - 163.3 1 2 0 0.0022 7 0 0 0 1.52E+07 1.29E+07 - - - 1.3127 0.9506 230117_WJC_METTL3_WT_vs_EV_F07.16408.16408.2 0.0442 18-Jul F.LLVGTQIDLR.D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1126.671 1.53 58425 16408 2 1126.67233 564.3428 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.84 3304.1 - 114668 - - - 1.1725 - 1.767 0.304 - 137.5 1 1 0 0.0013 10 0 0 0 6.16E+06 4.02E+06 - - - 2.875 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.16411.16411.2 0.156 12-Aug K.FDSLLLR.E "sp|Q8N5A5|ZGPAT_HUMAN,tr|A0A0J9YYD9|A0A0J9YYD9_HUMAN,tr|V9GY48|V9GY48_HUMAN" 3 862.4913 0.14 58426 16411 2 862.493626 432.2529 Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3 5.84 3304.5 - 3.18E+06 - - - 2.7513 - 1.865 0.248 - 232.6 1 2 0 0.0024 7 0 0 0 1.46E+08 1.08E+09 - - - 2.8468 0.9734 230117_WJC_METTL3_WT_vs_EV_F07.16414.16414.2 0.621 16-May K.VILTSPLIR[166.11].D sp|Q96SI9|STRBP_HUMAN 1 1020.6571 2.19 58428 16414 2 1020.656605 511.3358 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 9.72 3304.8 - 977862 - - - -0.4722 - 1.121 0.137 - 56.6 2 2 0 -0.0005 9 0 0 0 5.98E+07 2.73E+07 - - - 0.2487 0.9851 230117_WJC_METTL3_WT_vs_EV_F07.16423.16423.2 10.5 16-Aug K.GLDYGGVAR[166.11].E "sp|P46934|NEDD4_HUMAN,sp|Q96PU5|NED4L_HUMAN,sp|Q96J02|ITCH_HUMAN,sp|Q9HCE7|SMUF1_HUMAN,sp|Q9HAU4|SMUF2_HUMAN,tr|H0Y8X6|H0Y8X6_HUMAN,tr|A0A6Q8PG51|A0A6Q8PG51_HUMAN,tr|A0A1W2PNZ8|A0A1W2PNZ8_HUMAN,tr|A0A6Q8PG81|A0A6Q8PG81_HUMAN,tr|A0A590UK95|A0A590UK95_HUMAN,tr|A0A6Q8PHJ5|A0A6Q8PHJ5_HUMAN,tr|K7ERN1|K7ERN1_HUMAN,tr|A0A590UJQ1|A0A590UJQ1_HUMAN,tr|A0A1B0GVY1|A0A1B0GVY1_HUMAN,tr|J3QQM4|J3QQM4_HUMAN,tr|A0A6Q8PGP5|A0A6Q8PGP5_HUMAN,tr|A0A590UJW8|A0A590UJW8_HUMAN,tr|A0A6Q8PFI7|A0A6Q8PFI7_HUMAN,tr|A0A7P0Z498|A0A7P0Z498_HUMAN" 19 916.4642 2.47 58432 16423 2 916.463941 459.2394 E3 ubiquitin-protein ligase NEDD4 OS=Homo sapiens OX=9606 GN=NEDD4 PE=1 SV=4 5.84 3306 - 1.23E+06 - - - -0.2826 - 1.242 0.123 - 130.1 1 2 0 -0.0003 9 0 0 0 6.34E+07 2.57E+07 - - - 0.5764 0.9969 230117_WJC_METTL3_WT_vs_EV_F07.16427.16427.2 0.0722 14-Aug K.VLTFDLTK.Y "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 935.5328 2.9 58434 16427 2 935.532988 468.7737 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.81 3306.5 - 4.77E+06 - - - 0.2181 - 1.327 0.23 - 193.5 1 2 0 0.0002 8 0 0 0 7.83E+07 2.70E+07 - - - 1.593 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.16428.16428.2 0.868 12-Jul K.LIIFDAR.Q "sp|Q13613|MTMR1_HUMAN,tr|Q8NEC6|Q8NEC6_HUMAN,tr|F8WA39|F8WA39_HUMAN,tr|H0YDX3|H0YDX3_HUMAN" 4 846.4963 3.95 58435 16428 2 846.497712 424.2554 Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4 5.84 3306.6 - 3.33E+06 - - - 1.622 - 1.458 0.17 - 172.7 1 2 0 0.0014 7 0 0 0 1.12E+08 2.83E+07 - - - 1.4909 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.16429.16429.2 0.09 16-Nov R.IGLINDMVR[166.11].F sp|Q14152|EIF3A_HUMAN 1 1039.5724 1.51 58436 16429 2 1039.57457 520.7935 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.84 3306.7 - 2.87E+06 - - - 2.1153 - 1.81 0.198 - 349.5 1 2 0 0.0022 9 0 0 0 1.12E+08 7.43E+07 - - - 2.2193 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.16432.16432.2 8.10E-05 22-Nov R.VFASELNAGIIK[136.11].T "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1268.722 2.02 58439 16432 2 1268.724204 635.3683 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.97 3307.1 - 587958 - - - 1.7466 - 2.001 0.428 - 311.3 1 2 0 0.0022 12 0 0 0 1.79E+07 8.86E+06 - - - 4.0266 0.9287 230117_WJC_METTL3_WT_vs_EV_F07.16434.16434.2 0.639 20-Apr K.THGSEYYEC[160.03]SR[166.11].Y sp|O95376|ARI2_HUMAN 1 1397.5545 0.001 58441 16434 2 1397.560552 699.7846 E3 ubiquitin-protein ligase ARIH2 OS=Homo sapiens OX=9606 GN=ARIH2 PE=1 SV=1 5.37 3307.3 - 179697 - - - 4.2954 - 0.73 0.276 - 12.8 2 2 0 0.006 11 0 0 0 0.00E+00 4.72E+06 - - - 0.0918 0.9919 230117_WJC_METTL3_WT_vs_EV_F07.16438.16438.2 0.0708 16-Jul R.IGFGSFVEK.T "sp|P05556|ITB1_HUMAN,sp|P18564|ITB6_HUMAN,tr|A0A7I2V2F9|A0A7I2V2F9_HUMAN,tr|A0A087WXP3|A0A087WXP3_HUMAN,tr|A0A7I2V5T3|A0A7I2V5T3_HUMAN,tr|H7C4K3|H7C4K3_HUMAN,tr|E7EUI6|E7EUI6_HUMAN,tr|E9PEE8|E9PEE8_HUMAN,tr|A0A7I2V5Z8|A0A7I2V5Z8_HUMAN,tr|A0A7I2V348|A0A7I2V348_HUMAN,tr|C9JPK5|C9JPK5_HUMAN" 11 982.5124 2.41 58443 16438 2 982.51033 492.2635 Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1 PE=1 SV=2 6 3307.9 - 490725 - - - -2.0895 - 1.358 0.279 - 82 1 2 0 -0.0021 9 0 0 0 2.34E+07 9.71E+06 - - - 1.9864 1 230117_WJC_METTL3_WT_vs_EV_F07.16443.16443.2 4.22E-05 22-Dec K.VLVALASEELAK[136.11].G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1249.7373 1.64 58446 16443 2 1249.737796 625.8759 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.53 3308.5 - 929820 - - - 0.3937 - 2.41 0.518 - 433.3 1 2 0 0.0005 12 0 0 0 4.25E+07 2.59E+07 - - - 5.1812 0.9316 230117_WJC_METTL3_WT_vs_EV_F07.16451.16451.2 2.64 12-May R.VWQILER[166.11].T sp|Q93100|KPBB_HUMAN 1 952.537 0.82 58451 16451 2 952.536634 477.2758 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 5.97 3309.5 - 1.88E+06 - - - -0.3538 - 1.227 0.012 - 84.9 3 2 0 -0.0003 7 0 0 0 2.40E+07 2.93E+07 - - - -0.4354 0.9912 230117_WJC_METTL3_WT_vs_EV_F07.16456.16456.2 0.559 12-Jul K.LMFEELR[166.11].N sp|Q9Y3I0|RTCB_HUMAN 1 946.4822 1.06 58454 16456 2 946.482584 474.2484 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.53 3310.1 - 3.70E+06 - - - 0.449 - 1.079 0.19 - 129.5 1 2 0 0.0004 7 0 0 0 1.59E+08 1.51E+08 - - - 0.6851 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.16457.16457.2 0.000588 22-Nov K.VLVALASEELAK.G "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1241.7231 1.64 58455 16457 2 1241.72313 621.8688 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.53 3310.3 - 1.39E+06 - - - 0.0209 - 2.013 0.362 - 333.6 1 2 0 0 12 0 0 0 4.25E+07 2.59E+07 - - - 3.5556 0.988 230117_WJC_METTL3_WT_vs_EV_F07.16462.16462.2 0.296 12-Jul K.LWYTLDR.A sp|P00387|NB5R3_HUMAN 1 965.4971 1.91 58458 16462 2 965.494252 483.7558 NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3 5.84 3310.9 - 481793 - - - -2.9156 - 1.435 0.259 - 156.1 1 2 0 -0.0028 7 0 0 0 7.02E+07 3.68E+07 - - - 2.0975 0.9965 230117_WJC_METTL3_WT_vs_EV_F07.16463.16463.2 0.0424 16-Aug R.SAVYPLLYR.D "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H7C184|H7C184_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1080.5968 1.77 58459 16463 2 1080.594395 541.3057 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 8.31 3311.1 - 502935 - - - -2.208 - 1.735 0.319 - 261.7 1 2 0 -0.0024 9 0 0 0 2.84E+07 1.61E+07 - - - 2.9905 1 230117_WJC_METTL3_WT_vs_EV_F07.16468.16468.2 0.000747 20-Dec R.LLTGVEYVVGR.K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1204.6816 1.78 58462 16468 2 1204.686255 603.3481 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3311.7 - 665644 - - - 3.8865 - 2.499 0.511 - 435.2 1 2 0 0.0047 11 0 0 0 2.83E+07 1.59E+07 - - - 5.2915 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.16476.16476.2 0.0955 20-Aug K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 0.92 58468 16476 2 1235.761651 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3312.7 - 1.50E+06 - - - 1.2082 - 1.762 0.088 - 183.3 1 2 0 0.0015 11 0 0 0 6.38E+07 6.91E+07 - - - 1.2229 1 230117_WJC_METTL3_WT_vs_EV_F07.16477.16477.2 0.000449 20-Nov R.LLTGVEYVVGR[166.11].K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1214.6898 1.94 58469 16477 2 1214.689889 608.3522 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3312.8 - 776322 - - - 0.0379 - 2.285 0.456 - 365.2 1 2 0 0 11 0 0 0 3.10E+07 1.59E+07 - - - 4.6445 0.9936 230117_WJC_METTL3_WT_vs_EV_F07.16490.16490.2 0.000146 12-Jul R.EAYYWLR[166.11].H sp|P46977|STT3A_HUMAN 1 1009.4897 1.29 58478 16490 2 1009.490322 505.7521 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6.1 3314.4 - 1.23E+06 - - - 0.629 - 1.473 0.082 - 197 1 2 0 0.0006 7 0 0 0 6.84E+07 5.31E+07 - - - 0.8736 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.16492.16492.2 0.137 18-Oct K.LVALAVIDEK.N sp|Q96JJ7|TMX3_HUMAN 1 1069.6383 1.7 58480 16492 2 1069.638399 535.8264 Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2 4.37 3314.6 - 384953 - - - 0.0823 - 1.743 0.209 - 162.7 1 2 0 0.0001 10 0 0 0 1.18E+07 6.93E+06 - - - 2.1355 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.16497.16497.2 0.0789 14-Sep K.VTNLLMLK[136.11].G "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|B4DI28|B4DI28_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|X6R242|X6R242_HUMAN,tr|A0A6Q8PH43|A0A6Q8PH43_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 18 938.5714 1.21 58483 16497 2 938.571475 470.293 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.72 3315.2 - 1.37E+07 - - - 0.0543 - 1.891 0.317 - 249.7 1 2 0 0.0001 8 0 0 0 9.99E+08 8.25E+08 - - - 3.3038 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.16498.16498.2 0.0565 12-Jul K.LWVLETK[136.11].E "sp|Q15061|WDR43_HUMAN,tr|C9JEE7|C9JEE7_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 3 895.5259 5.01 58484 16498 2 895.52499 448.7702 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3315.2 - 1.35E+06 - - - -0.9648 - 1.611 0.219 - 177.8 1 2 0 -0.0009 7 0 0 0 3.35E+08 6.69E+07 - - - 2.1692 0.996 230117_WJC_METTL3_WT_vs_EV_F07.16503.16503.2 1.15 12-Jul M.LPLSLLK.T "sp|Q9Y4Z0|LSM4_HUMAN,sp|Q969I6|S38A4_HUMAN,tr|F8VQY9|F8VQY9_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 5 782.5266 16.78 58488 16503 2 782.526886 392.2706 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 8.75 3316 - 1.06E+06 - - - 0.3962 - 1.69 0.082 - 135.5 1 2 0 0.0003 7 0 0 0 1.85E+07 1.10E+06 - - - 1.3092 0.9902 230117_WJC_METTL3_WT_vs_EV_F07.16507.16507.2 0.131 12-Aug R.EAYYWLR.H sp|P46977|STT3A_HUMAN 1 999.4814 1.3 58491 16507 2 999.480588 500.748 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6.1 3316.4 - 3.45E+06 - - - -0.8294 - 1.313 0.167 - 288.7 1 2 0 -0.0008 7 0 0 0 6.94E+07 5.33E+07 - - - 1.137 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.16513.16513.2 0.0124 12-Jun K.LWYTLDR[166.11].A sp|P00387|NB5R3_HUMAN 1 975.5053 1.91 58496 16513 2 975.505722 488.7599 NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3 5.84 3317.1 - 1.19E+06 - - - 0.3947 - 1.589 0.158 - 140.2 1 2 0 0.0004 7 0 0 0 6.99E+07 3.67E+07 - - - 1.6752 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.16515.16515.2 0.138 20-Oct R.IDALLAVDPPR.A sp|P50219|MNX1_HUMAN 1 1178.6659 2.37 58497 16515 2 1178.66765 590.3402 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3317.3 - 1.53E+06 - - - 1.4652 - 2.289 0.302 - 311.7 1 2 0 0.0017 11 0 0 0 5.51E+07 2.32E+07 - - - 3.5113 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.16517.16517.2 0.000883 16-Aug R.SLFVVVGDR.G "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 990.5498 0.57 58499 16517 2 990.55192 496.2822 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.55 3317.5 - 610229 - - - 2.1089 - 1.996 0.415 - 198.1 1 2 0 0.0021 9 0 0 0 2.96E+07 5.17E+07 - - - 4.1051 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.16532.16532.2 4.25 14-Jul R.ALDIPLVK[136.11].N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 875.5572 1.31 58508 16532 2 875.558461 438.7859 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3319.2 - 2.28E+06 - - - 1.4928 - 1.421 0.224 - 141.8 1 2 0 0.0013 8 0 0 0 1.57E+08 1.20E+08 - - - 1.7547 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.16534.16534.2 0.00226 16-Oct R.SPVYLTVLK[136.11].H "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1026.6205 1.66 58510 16534 2 1026.622106 514.3175 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 8.31 3319.5 - 433465 - - - 1.5809 - 1.974 0.356 - 251.7 1 2 0 0.0016 9 0 0 0 2.64E+07 1.59E+07 - - - 3.6374 0.9862 230117_WJC_METTL3_WT_vs_EV_F07.16535.16535.2 3.18 16-Aug R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 0.6 58511 16535 2 960.612649 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3319.6 - 408284 - - - 2.843 - 1.195 0.142 - 115.7 1 2 0 0.0027 9 0 0 0 8.61E+06 1.44E+07 - - - 0.6043 0.9436 230117_WJC_METTL3_WT_vs_EV_F07.16537.16537.2 13.2 12-Jun K.IFELGLK.K "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 818.4902 0.35 58512 16537 2 818.490096 410.2524 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 6 3319.9 - 421696 - - - -0.1161 - 1.187 0.003 - 88.2 1 2 0 -0.0001 7 0 0 0 1.83E+07 5.20E+07 - - - -0.3937 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.16539.16539.2 0.0689 12-Aug K.FVSFLGR[166.11].T "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 834.4627 1.31 58513 16539 2 834.462351 418.2386 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 9.75 3320.1 - 4.32E+06 - - - -0.471 - 1.503 0.338 - 221.5 1 2 0 -0.0004 7 0 0 0 3.76E+08 2.87E+08 - - - 2.8284 1 230117_WJC_METTL3_WT_vs_EV_F07.16543.16543.2 0.000101 14-Oct K.VIFLENYR.V "sp|P06737|PYGL_HUMAN,sp|P11217|PYGM_HUMAN,sp|P11216|PYGB_HUMAN,tr|E9PK47|E9PK47_HUMAN,tr|H0Y4Z6|H0Y4Z6_HUMAN" 5 1052.5655 4.87 58516 16543 2 1052.565637 527.29 "Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL PE=1 SV=4" 5.97 3320.4 - 3.11E+06 - - - 0.1482 - 1.989 0.545 - 414.4 1 2 0 0.0002 8 0 0 0 9.54E+07 1.96E+07 - - - 5.1402 0.997 230117_WJC_METTL3_WT_vs_EV_F07.16545.16545.2 0.0642 20-Oct R.IDALLAVDPPR[166.11].A sp|P50219|MNX1_HUMAN 1 1188.6742 2.38 58518 16545 2 1188.680019 595.3444 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3320.6 - 630866 - - - 4.9013 - 2.214 0.289 - 303.5 1 2 0 0.0058 11 0 0 0 5.51E+07 2.31E+07 - - - 3.3238 0.9886 230117_WJC_METTL3_WT_vs_EV_F07.16548.16548.2 0.0406 22-Jul R.MPGSVIPPPLVR.G sp|Q86YP4|P66A_HUMAN 1 1261.7217 2.19 58521 16548 2 1261.720085 631.8681 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.5 3321 - 280605 - - - -1.2515 - 1.268 0.211 - 106.3 1 2 0 -0.0016 12 0 0 0 9.56E+06 4.37E+06 - - - 1.2237 1 230117_WJC_METTL3_WT_vs_EV_F07.16552.16552.2 0.000656 16-Sep K.GPLMMYISK.M sp|P13639|EF2_HUMAN 1 1038.5242 0.16 58524 16552 2 1038.523851 520.2694 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 3321.5 - 2.14E+06 - - - -0.3457 - 2.054 0.469 - 389.7 1 2 0 -0.0004 9 0 0 0 7.17E+07 4.50E+08 - - - 4.5873 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.16554.16554.2 0.0149 18-Jun K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 24.15 58525 16554 2 1146.630267 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3321.7 - 9.23E+06 - - - 1.5628 - 1.179 0.284 - 90.5 1 2 0 0.0018 10 0 0 0 2.31E+08 9.56E+06 - - - 1.5977 0.9923 230117_WJC_METTL3_WT_vs_EV_F07.16555.16555.2 0.622 14-Aug R.ALDIPLVK.N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 867.543 1.32 58526 16555 2 867.544538 434.7788 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3321.8 - 5.66E+06 - - - 1.8258 - 1.282 0.123 - 240.9 1 2 0 0.0016 8 0 0 0 1.62E+08 1.23E+08 - - - 0.6982 0.9208 230117_WJC_METTL3_WT_vs_EV_F07.16557.16557.2 0.00652 12-Jul Q.AAILHLK[136.11].R "sp|Q68DA7|FMN1_HUMAN,sp|Q8NHP7|EXD1_HUMAN,tr|H0YM30|H0YM30_HUMAN,tr|A0A5F9ZHS8|A0A5F9ZHS8_HUMAN" 4 772.5051 1.8 58528 16557 2 772.50552 387.2598 Formin-1 OS=Homo sapiens OX=9606 GN=FMN1 PE=1 SV=3 8.8 3321.9 - 1.71E+06 - - - 0.5968 - 1.42 0.309 - 201.6 1 1 0 0.0005 7 0 0 0 1.05E+08 5.81E+07 - - - 2.4342 0.9944 230117_WJC_METTL3_WT_vs_EV_F07.16577.16577.2 0.338 14-Apr K.VIILSLDR.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 927.5753 2.31 58542 16577 2 927.576301 464.7949 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.81 3324.3 - 2.26E+07 - - - 1.0608 - 1.023 0.243 - 79.1 1 2 0 0.001 8 0 0 0 2.94E+08 1.27E+08 - - - 0.9041 0.9674 230117_WJC_METTL3_WT_vs_EV_F07.16582.16582.2 0.00194 26-Sep F.LLIGGGTAAFAAAR.S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1287.7299 5.82 58547 16582 2 1287.733341 644.8722 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3324.6 - 287164 - - - 2.6566 - 2.03 0.466 - 209.4 1 1 0 0.0034 14 0 0 0 1.31E+07 2.25E+06 - - - 4.2586 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.16585.16585.2 0.00106 16-Sep K.GLIDYETFK.E sp|P15924|DESP_HUMAN 1 1084.5441 12.85 58548 16585 2 1084.545572 543.2793 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3325 - 769360 - - - 1.3785 - 1.843 0.387 - 192 1 2 0 0.0015 9 0 0 0 9.34E+06 7.27E+05 - - - 3.6677 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.16587.16587.2 0.000361 18-Aug K.AAPEMVSLLK[136.11].R "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN,tr|K7EQ99|K7EQ99_HUMAN" 3 1065.5984 1.24 58550 16587 2 1065.601204 533.8065 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 6.05 3325.3 - 1.54E+06 - - - 2.6624 - 1.602 0.43 - 204 1 2 0 0.0028 10 0 0 0 5.49E+07 4.44E+07 - - - 3.5315 1 230117_WJC_METTL3_WT_vs_EV_F07.16588.16588.2 8.63E-05 16-Sep K.GPLMMYISK[136.11].M sp|P13639|EF2_HUMAN 1 1046.5384 0.13 58551 16588 2 1046.540383 524.2765 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 3325.4 - 1.02E+06 - - - 1.8853 - 1.895 0.516 - 309.1 1 2 0 0.002 9 0 0 0 7.48E+07 5.86E+08 - - - 4.7009 0.9941 230117_WJC_METTL3_WT_vs_EV_F07.16589.16589.2 0.121 16-Aug K.NAIVVLIPK[136.11].Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 973.6416 2.29 58552 16589 2 973.644294 487.8281 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3325.6 - 230196 - - - 2.8152 - 1.079 0.266 - 100.6 1 2 0 0.0027 9 0 0 0 2.15E+08 9.40E+07 - - - 1.2248 0.9795 230117_WJC_METTL3_WT_vs_EV_F07.16595.16595.2 3.38 12-Jun R.SFDLLVK[136.11].N sp|Q9HB71|CYBP_HUMAN 1 828.4837 2.05 58557 16595 2 828.484166 415.2491 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 5.55 3326.2 - 3.53E+06 - - - 0.6168 - 1.104 0.096 - 127 1 2 0 0.0005 7 0 0 0 1.28E+08 6.22E+07 - - - 0.0634 0.9852 230117_WJC_METTL3_WT_vs_EV_F07.16596.16596.2 2.47 12-Jul K.LPLLLSR.M "sp|P49902|5NTC_HUMAN,sp|O95866|G6B_HUMAN,tr|A0A140T9L8|A0A140T9L8_HUMAN,tr|A0A6Q8PHB5|A0A6Q8PHB5_HUMAN,tr|A0A140T9V1|A0A140T9V1_HUMAN,tr|A0A6Q8PHP0|A0A6Q8PHP0_HUMAN,tr|B7ZLJ5|B7ZLJ5_HUMAN,tr|A0A0G2JJG8|A0A0G2JJG8_HUMAN,tr|F8WDG3|F8WDG3_HUMAN,tr|Q5JUV4|Q5JUV4_HUMAN" 10 810.5327 0.81 58558 16596 2 810.535373 406.2736 Cytosolic purine 5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5C2 PE=1 SV=1 9.75 3326.3 - 1.27E+06 - - - 3.2682 - 1.552 0.041 - 210.3 1 2 0 0.0026 7 0 0 0 1.69E+07 2.09E+07 - - - 0.7357 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.16597.16597.2 0.506 14-Jul K.LLELLPGK[136.11].V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 889.5728 2.34 58559 16597 2 889.574434 445.7937 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3326.5 - 650730 - - - 1.8312 - 1.138 0.224 - 117.4 1 2 0 0.0016 8 0 0 0 1.03E+08 4.41E+07 - - - 1.0848 0.9956 230117_WJC_METTL3_WT_vs_EV_F07.16598.16598.2 0.948 16-Jul K.IVGNLLYYR.Y "sp|Q13576|IQGA2_HUMAN,tr|F5H7S7|F5H7S7_HUMAN,tr|E7EWC2|E7EWC2_HUMAN" 3 1109.6233 2.69 58560 16598 2 1109.625428 555.8189 Ras GTPase-activating-like protein IQGAP2 OS=Homo sapiens OX=9606 GN=IQGAP2 PE=1 SV=4 8.59 3326.6 - 295024 - - - 1.8907 - 1.345 0.166 - 73 1 2 0 0.0021 9 0 0 0 2.57E+06 9.55E+05 - - - 1.1239 0.9033 230117_WJC_METTL3_WT_vs_EV_F07.16600.16600.2 0.0527 26-Oct F.LLIGGGTAAFAAAR[166.11].S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1297.7382 5.82 58562 16600 2 1297.743566 649.8764 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3326.8 - 238692 - - - 4.1426 - 2.093 0.396 - 221.5 1 1 0 0.0054 14 0 0 0 1.31E+07 2.25E+06 - - - 3.8176 0.9094 230117_WJC_METTL3_WT_vs_EV_F07.16601.16601.2 0.0678 22-Jun R.MPGSVIPPPLVR[166.11].G sp|Q86YP4|P66A_HUMAN 1 1271.7299 2.19 58563 16601 2 1271.740096 636.8722 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.5 3327 - 180616 - - - 7.9907 - 1.436 0.216 - 86.4 1 2 0 0.0102 12 0 0 0 9.56E+06 4.37E+06 - - - 1.5853 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.16605.16605.2 0.0762 16-Sep K.FGLFTPGSR[166.11].L "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 990.5162 0.43 58565 16605 2 990.51768 496.2654 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 9.75 3327.5 - 1.68E+06 - - - 1.4578 - 1.95 0.271 - 245.5 1 2 0 0.0014 9 0 0 0 1.98E+08 4.62E+08 - - - 2.9742 0.9919 230117_WJC_METTL3_WT_vs_EV_F07.16613.16613.2 0.0671 12-Jul K.YYTLFGR[166.11].S sp|P07814|SYEP_HUMAN 1 928.4682 1.11 58571 16613 2 928.471011 465.2414 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.59 3328.5 - 5.84E+06 - - - 3.0028 - 1.346 0.147 - 155.4 1 2 0 0.0028 7 0 0 0 1.27E+08 1.14E+08 - - - 1.0674 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.16614.16614.2 0.209 14-Sep R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 1454.81 58572 16614 2 1000.561209 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3328.6 - 1.13E+06 - - - 1.875 - 2.026 0.251 - 224.7 1 2 0 0.0019 8 0 0 0 1.13E+08 7.75E+04 - - - 3.0238 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.16623.16623.2 0.319 16-Jul R.LIPDFPVAR.S sp|Q96S55|WRIP1_HUMAN 1 1026.5862 5.7 58579 16623 2 1026.587865 514.3004 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 5.84 3329.5 - 1.15E+06 - - - 1.6063 - 1.38 0.196 - 153.2 1 2 0 0.0016 9 0 0 0 6.09E+07 1.07E+07 - - - 1.4199 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.16631.16631.2 0.542 14-Aug K.LLELLPGK.V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 881.5586 2.37 58585 16631 2 881.561054 441.7866 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3330.5 - 4.11E+06 - - - 2.778 - 1.64 0.213 - 208.6 1 2 0 0.0024 8 0 0 0 1.05E+08 4.41E+07 - - - 2.1054 0.9752 230117_WJC_METTL3_WT_vs_EV_F07.16632.16632.2 1.05 16-Aug R.ALAYFEQLK.L "sp|O43592|XPOT_HUMAN,tr|F5GYW6|F5GYW6_HUMAN,tr|F8WDU6|F8WDU6_HUMAN" 3 1081.5808 3.36 58586 16632 2 1081.585831 541.7977 Exportin-T OS=Homo sapiens OX=9606 GN=XPOT PE=1 SV=2 6.05 3330.6 - 539681 - - - 4.6543 - 1.467 0.121 - 167.4 1 2 0 0.005 9 0 0 0 6.52E+06 1.94E+06 - - - 1.0418 0.9022 230117_WJC_METTL3_WT_vs_EV_F07.16633.16633.2 0.121 20-Jul R.LVMELSGEMVR.K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1262.6363 2.14 58587 16633 2 1262.644798 632.3254 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3330.8 - 423514 - - - 6.747 - 1.205 0.198 - 80.8 1 2 0 0.0085 11 0 0 0 1.03E+07 4.84E+06 - - - 1.0052 1 230117_WJC_METTL3_WT_vs_EV_F07.16634.16634.2 0.000267 20-Dec K.NALESYAFNMK.S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1286.5965 15.83 58588 16634 2 1286.601727 644.3055 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3330.9 - 389790 - - - 4.0448 - 2.213 0.475 - 560.9 1 2 0 0.0052 11 0 0 0 2.40E+07 1.52E+06 - - - 4.6966 0.996 230117_WJC_METTL3_WT_vs_EV_F07.16635.16635.2 0.0193 12-Jun K.LFDFPGR.G sp|Q9P258|RCC2_HUMAN 1 850.4337 1.97 58589 16635 2 850.433589 426.2241 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.84 3331 - 297436 - - - -0.1752 - 1.275 0.234 - 91.5 1 2 0 -0.0001 7 0 0 0 2.75E+08 1.39E+08 - - - 1.5391 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.16638.16638.2 0.0263 20-Jul R.LVMELSGEMVR[166.11].K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1272.6445 2.14 58592 16638 2 1272.64557 637.3296 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3331.4 - 196738 - - - 0.8023 - 1.57 0.234 - 133.9 2 2 0 0.001 11 0 0 0 1.03E+07 4.84E+06 - - - 1.8548 0.998 230117_WJC_METTL3_WT_vs_EV_F07.16645.16645.2 0.019 16-Sep K.FGLFTPGSR.L "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 980.508 0.43 58597 16645 2 980.512381 491.2613 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 9.75 3332.1 - 9.29E+06 - - - 4.5028 - 1.781 0.385 - 286.5 1 2 0 0.0044 9 0 0 0 1.98E+08 4.63E+08 - - - 3.553 0.999 230117_WJC_METTL3_WT_vs_EV_F07.16646.16646.2 0.000832 16-Nov K.NAIVVLIPK.Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 965.6274 2.29 58598 16646 2 965.631142 483.821 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3332.2 - 7.04E+06 - - - 3.9239 - 2.017 0.418 - 531 1 2 0 0.0038 9 0 0 0 2.15E+08 9.40E+07 - - - 4.157 0.8995 230117_WJC_METTL3_WT_vs_EV_F07.16647.16647.2 1.98 12-Jun K.NLFELAR.Q "sp|Q9UN37|VPS4A_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 2 861.4709 4.58 58599 16647 2 861.474903 431.7427 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 6 3332.2 - 3.65E+06 - - - 4.7024 - 1.083 0.118 - 143.7 2 2 0 0.0041 7 0 0 0 5.18E+07 1.13E+07 - - - 0.0295 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.16648.16648.2 0.0141 16-Sep R.LTQEVLLLR.E "sp|Q5VU43|MYOME_HUMAN,tr|E9PQG4|E9PQG4_HUMAN,tr|A0A087WX83|A0A087WX83_HUMAN,tr|A0A075B749|A0A075B749_HUMAN" 4 1083.6652 2.91 58600 16648 2 1083.668588 542.8399 Myomegalin OS=Homo sapiens OX=9606 GN=PDE4DIP PE=1 SV=3 6 3332.4 - 999377 - - - 3.131 - 2.071 0.218 - 217.3 1 2 0 0.0034 9 0 0 0 1.22E+07 4.18E+06 - - - 2.7563 0.987 230117_WJC_METTL3_WT_vs_EV_F07.16652.16652.2 2.95 18-Jun R.LLPQVDSVLK.S "sp|Q9C0B9|ZCHC2_HUMAN,tr|K7EKB8|K7EKB8_HUMAN,tr|K7ESN2|K7ESN2_HUMAN" 3 1110.6649 4.73 58604 16652 2 1110.667701 556.3397 Zinc finger CCHC domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZCCHC2 PE=1 SV=6 5.84 3332.9 - 281061 - - - 2.557 - 1.151 0.149 - 59.8 1 2 0 0.0028 10 0 0 0 2.00E+06 4.24E+05 - - - 0.5332 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.16655.16655.2 0.0057 20-Jul K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.27 58606 16655 2 1245.771136 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3333.2 - 905345 - - - 2.1738 - 1.41 0.385 - 94.6 1 2 0 0.0027 11 0 0 0 3.07E+07 2.41E+07 - - - 2.8133 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.16658.16658.2 0.173 14-Aug K.ALDYYMLR.N sp|Q9Y490|TLN1_HUMAN 1 1043.511 3.7 58608 16658 2 1043.509861 522.7628 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.88 3333.6 - 459036 - - - -1.0934 - 1.472 0.276 - 202.6 1 2 0 -0.0011 8 0 0 0 3.48E+07 9.41E+06 - - - 2.2452 0.99 230117_WJC_METTL3_WT_vs_EV_F07.16659.16659.2 0.0553 12-Aug K.VFDLLNR.K "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|H0Y8H2|H0Y8H2_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 875.4865 1.59 58609 16659 2 875.48738 438.7505 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 5.81 3333.7 - 1.46E+06 - - - 1.0029 - 1.343 0.07 - 219.2 1 2 0 0.0009 7 0 0 0 2.93E+07 1.85E+07 - - - 0.4922 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.16660.16660.2 0.00614 20-Oct K.LISSVDPQFLK.L "sp|Q9BVG4|PBDC1_HUMAN,tr|A6NDF3|A6NDF3_HUMAN" 2 1245.6969 12.36 58610 16660 2 1245.698281 623.8557 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 5.84 3333.8 - 797544 - - - 1.1174 - 1.463 0.301 - 220.9 1 2 0 0.0014 11 0 0 0 3.44E+07 2.78E+06 - - - 2.2931 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.16665.16665.2 0.0129 16-Oct R.LLQSLLDTR.C sp|Q13045|FLII_HUMAN 1 1057.6132 1.32 58613 16665 2 1057.615551 529.8139 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3334.4 - 560668 - - - 2.2617 - 2.005 0.297 - 327.7 1 2 0 0.0024 9 0 0 0 1.59E+07 1.20E+07 - - - 3.2464 0.9912 230117_WJC_METTL3_WT_vs_EV_F07.16670.16670.2 0.287 16-Jun R.FLIIDEADR.M sp|Q8N8A6|DDX51_HUMAN 1 1090.5659 1.07 58616 16670 2 1090.566053 546.2902 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 4.03 3335 - 2.35E+06 - - - 0.1632 - 1.194 0.184 - 111.6 2 2 0 0.0002 9 0 0 0 2.65E+07 2.49E+07 - - - 0.7785 0.9227 230117_WJC_METTL3_WT_vs_EV_F07.16672.16672.2 0.515 16-Aug K.DVEIPLDSK[136.11].P "sp|Q16363|LAMA4_HUMAN,tr|A0A0A0MQS9|A0A0A0MQS9_HUMAN,tr|A0A494C139|A0A494C139_HUMAN,tr|A0A0A0MTC7|A0A0A0MTC7_HUMAN" 4 1022.5375 0 58618 16672 2 1022.539331 512.276 Laminin subunit alpha-4 OS=Homo sapiens OX=9606 GN=LAMA4 PE=1 SV=4 4.03 3335.1 - 2.99E+06 - - - 1.7505 - 1.579 0.272 - 125.3 1 1 0 0.0018 9 0 0 0 4.82E+06 1.00E+09 - - - 2.371 0.998 230117_WJC_METTL3_WT_vs_EV_F07.16692.16692.2 0.157 20-Aug R.VPLIGSLPEAR[166.11].L "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN,tr|K7EQG1|K7EQG1_HUMAN" 3 1160.6793 0.73 58632 16692 2 1160.680079 581.3469 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 5.97 3337.5 - 0 - - - 0.6893 - 1.792 0.162 - 169.2 1 2 0 0.0008 11 0 0 0 1.95E+06 2.67E+06 - - - 1.8153 0.9883 230117_WJC_METTL3_WT_vs_EV_F07.16706.16706.2 0.75 12-Jun R.DLIDYVR.Y "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 892.4654 3.87 58639 16706 2 892.465279 447.24 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.21 3339.3 - 1.32E+06 - - - -0.1714 - 1.054 0.202 - 161.1 1 2 0 -0.0002 7 0 0 0 1.13E+08 2.93E+07 - - - 0.6996 1 230117_WJC_METTL3_WT_vs_EV_F07.16732.16732.2 1.18E-07 13/22 K.VFGAAPLENVVR.K "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 1270.7034 7.26 58642 16732 2 1270.70087 636.359 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 5.97 3343.3 - 2.79E+06 - - - -1.9682 - 2.464 0.5 - 559.1 1 2 0 -0.0025 12 0 0 0 1.65E+08 2.27E+07 - - - 5.106 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.16757.16757.2 0.00779 24-Dec K.VLIIGGGDGGVLR.E "sp|P19623|SPEE_HUMAN,tr|K7ESL0|K7ESL0_HUMAN" 2 1224.719 36.52 58646 16757 2 1224.716809 613.3668 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.81 3347.1 - 3.78E+06 - - - -1.8061 - 2.045 0.377 - 444.5 1 2 0 -0.0022 13 0 0 0 1.63E+08 4.45E+06 - - - 3.6609 0.93 230117_WJC_METTL3_WT_vs_EV_F07.16760.16760.2 0.0843 12-Jul K.ELLIFNK[136.11].Q "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 883.5259 1.04 58647 16760 2 883.524587 442.7702 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.1 3347.5 - 5.27E+06 - - - -1.434 - 1.297 0.016 - 168.6 1 2 0 -0.0013 7 0 0 0 1.04E+09 9.96E+08 - - - -0.0172 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.16770.16770.2 0.0152 18-Jul K.IFFAGDTIPK[136.11].S "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 5 1115.6106 2.14 58650 16770 2 1115.610551 558.8126 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.84 3348.8 - 2.18E+06 - - - -0.0861 - 1.448 0.282 - 63.7 1 2 0 -0.0001 10 0 0 0 1.62E+08 7.54E+07 - - - 2.1571 0.9924 230117_WJC_METTL3_WT_vs_EV_F07.16773.16773.2 0.291 14-Aug K.AFALEVIK.S sp|Q9H2U2|IPYR2_HUMAN 1 889.5273 8.8 58651 16773 2 889.527767 445.7709 "Inorganic pyrophosphatase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PPA2 PE=1 SV=2" 6.05 3349.2 - 1.74E+06 - - - 0.5205 - 1.175 0.169 - 195.2 1 2 0 0.0005 8 0 0 0 9.54E+07 1.08E+07 - - - 0.7755 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.16780.16780.2 2.26E-05 18-Oct K.IFFAGDTIPK.S "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 5 1107.5964 2.14 58653 16780 2 1107.596748 554.8055 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.84 3350.1 - 3.75E+06 - - - 0.2718 - 1.988 0.475 - 218.1 1 2 0 0.0003 10 0 0 0 1.62E+08 7.54E+07 - - - 4.4672 0.9922 230117_WJC_METTL3_WT_vs_EV_F07.16782.16782.2 0.207 14-Jun R.VAFTLLEK.V "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 4 919.5379 11.13 58654 16782 2 919.535877 460.7762 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 5.97 3350.4 - 2.65E+06 - - - -2.1663 - 1.546 0.232 - 94 1 2 0 -0.002 8 0 0 0 1.08E+08 9.70E+06 - - - 2.0679 0.9922 230117_WJC_METTL3_WT_vs_EV_F07.16787.16787.2 2.14 18-Nov R.LYLINSPVVR.A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1172.6917 1.57 58655 16787 2 1172.687988 587.3531 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3351.1 - 2.90E+06 - - - -3.2029 - 2.044 0.234 - 541.6 1 2 0 -0.0038 10 0 0 0 5.78E+08 3.68E+08 - - - 2.7637 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.16789.16789.2 0.00129 18-Sep R.LYLINSPVVR[166.11].A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1182.7 1.57 58656 16789 2 1182.697016 592.3573 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3351.3 - 3.10E+06 - - - -2.5349 - 2.007 0.259 - 301.8 1 2 0 -0.003 10 0 0 0 5.78E+08 3.68E+08 - - - 2.8976 0.9951 230117_WJC_METTL3_WT_vs_EV_F07.16790.16790.2 0.00117 18-Sep R.VAAAVDLIIK.S "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1011.6328 1.93 58657 16790 2 1011.628805 506.8237 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3351.4 - 4.74E+06 - - - -3.9807 - 2.134 0.431 - 192.5 1 2 0 -0.004 10 0 0 0 9.74E+07 5.03E+07 - - - 4.3389 0.9857 230117_WJC_METTL3_WT_vs_EV_F07.16799.16799.2 0.728 14-Oct K.IPLGLDLK.N "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 867.543 1.83 58660 16799 2 867.541971 434.7788 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.84 3352.6 - 2.42E+06 - - - -1.1331 - 1.71 0.045 - 299.6 1 2 0 -0.001 8 0 0 0 1.77E+08 9.65E+07 - - - 0.9911 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.16801.16801.2 4.08E-05 18-Sep R.GTPLISPLIK.W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1037.6485 1.61 58661 16801 2 1037.645163 519.8315 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3352.8 - 2.60E+06 - - - -3.1986 - 1.784 0.48 - 342.8 1 2 0 -0.0033 10 0 0 0 3.14E+08 1.95E+08 - - - 4.201 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.16803.16803.2 0.000749 18-Sep R.GTPLISPLIK[136.11].W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1045.6627 1.61 58662 16803 2 1045.660744 523.8386 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3353.1 - 3.30E+06 - - - -1.8534 - 1.737 0.442 - 237.9 1 2 0 -0.0019 10 0 0 0 3.14E+08 1.95E+08 - - - 3.8462 1 230117_WJC_METTL3_WT_vs_EV_F07.16806.16806.2 5.53E-07 13/18 R.YGLAAAVFTR.D sp|P30837|AL1B1_HUMAN 1 1067.5764 5.35 58665 16806 2 1067.574139 534.7955 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 8.75 3353.4 - 1.78E+06 - - - -2.0991 - 2.529 0.421 - 591.2 1 2 0 -0.0022 10 0 0 0 1.11E+08 2.07E+07 - - - 4.7396 1 230117_WJC_METTL3_WT_vs_EV_F07.16810.16810.2 8.71E-08 13/22 R.GYISPYFINTSK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1388.6976 2.22 58666 16810 2 1388.69733 695.3561 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3354 - 3.09E+06 - - - -0.2067 - 2.454 0.507 - 615.1 1 2 0 -0.0003 12 0 0 0 1.03E+08 4.63E+07 - - - 5.1477 0.9937 230117_WJC_METTL3_WT_vs_EV_F07.16815.16815.2 0.0122 12-Jul K.FTVPMLK[136.11].E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 842.4815 0.99 58669 16815 2 842.480289 422.248 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3354.5 - 1.58E+06 - - - -1.4932 - 1.498 0.208 - 173.2 1 2 0 -0.0013 7 0 0 0 2.06E+08 2.08E+08 - - - 1.8574 0.9705 230117_WJC_METTL3_WT_vs_EV_F07.16823.16823.2 1.65 16-Jul K.GSLLPTSPR.L "tr|H7C179|H7C179_HUMAN,tr|H7C128|H7C128_HUMAN,tr|H7C127|H7C127_HUMAN" 3 926.5185 1.34 58672 16823 2 926.519132 464.2665 Bromodomain-containing protein 8 (Fragment) OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=1 9.75 3355.6 - 2.40E+06 - - - 0.6487 - 1.262 0.032 - 142.6 2 2 0 0.0006 9 0 0 0 3.10E+08 2.31E+08 - - - -0.1841 1 230117_WJC_METTL3_WT_vs_EV_F07.16825.16825.2 2.44E-05 20-Dec R.FGGLVLSPVGK.Q sp|Q9UJK0|TSR3_HUMAN 1 1072.6281 1.41 58673 16825 2 1072.625838 537.3213 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.75 3355.8 - 1.32E+06 - - - -2.0911 - 2.375 0.533 - 482.4 1 2 0 -0.0022 11 0 0 0 8.25E+07 5.86E+07 - - - 5.3171 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.16835.16835.2 0.00126 20-Nov R.FGGLVLSPVGK[136.11].Q sp|Q9UJK0|TSR3_HUMAN 1 1080.6423 1.5 58679 16835 2 1080.64424 541.3284 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.75 3357 - 1.73E+06 - - - 1.8128 - 2.242 0.451 - 353.3 1 2 0 0.002 11 0 0 0 8.22E+07 5.48E+07 - - - 4.5556 1 230117_WJC_METTL3_WT_vs_EV_F07.16837.16837.2 0.00094 13/20 Q.WGTLTDC[160.03]VVMR.D "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 14 1336.6268 0.95 58680 16837 2 1336.62712 669.3207 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.83 3357.2 - 1.05E+06 - - - 0.2559 - 2.284 0.479 - 578.7 1 1 0 0.0003 11 0 0 0 2.16E+07 2.27E+07 - - - 4.8131 0.9953 230117_WJC_METTL3_WT_vs_EV_F07.16841.16841.2 0.0333 12-Aug K.FTVPMLK.E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 834.4673 0.94 58682 16841 2 834.467033 418.2409 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3357.6 - 3.01E+06 - - - -0.3763 - 1.378 0.196 - 234 1 2 0 -0.0003 7 0 0 0 7.03E+07 7.48E+07 - - - 1.5045 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.16843.16843.2 0.0969 12-Sep R.FGIEIIK.W "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 818.4902 1.87 58684 16843 2 818.492405 410.2524 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 6 3357.9 - 2.44E+06 - - - 2.705 - 1.824 0.126 - 217.1 1 2 0 0.0022 7 0 0 0 5.88E+07 3.15E+07 - - - 1.8753 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.16844.16844.2 0.00928 20-Aug K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.09 58685 16844 2 1235.75803 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3358 - 1.64E+06 - - - -1.722 - 1.753 0.313 - 195.8 1 2 0 -0.0021 11 0 0 0 1.18E+08 1.09E+08 - - - 2.8707 0.9875 230117_WJC_METTL3_WT_vs_EV_F07.16848.16848.2 0.493 12-Jul R.FVAELWK[136.11].D sp|P35580|MYH10_HUMAN 1 899.4996 0.73 58687 16848 2 899.498641 450.7571 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3358.4 - 1.67E+06 - - - -1.1106 - 1.285 0.169 - 150.8 1 2 0 -0.001 7 0 0 0 1.19E+08 1.64E+08 - - - 1.0835 0.9901 230117_WJC_METTL3_WT_vs_EV_F07.16849.16849.2 0.982 12-Aug R.ILLQYLK.Q "sp|Q9P0U3|SENP1_HUMAN,sp|Q9NVH2|INT7_HUMAN" 2 889.5637 4.94 58688 16849 2 889.564699 445.7891 Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2 8.59 3358.6 - 2.26E+06 - - - 1.1343 - 1.15 0.135 - 175.4 1 2 0 0.001 7 0 0 0 3.71E+07 7.50E+06 - - - 0.4806 0.999 230117_WJC_METTL3_WT_vs_EV_F07.16850.16850.2 0.0453 12-Jun K.LMIWDTR.S "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 933.4742 1.43 58689 16850 2 933.475029 467.7444 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3358.6 - 5.12E+06 - - - 0.8634 - 1.336 0.332 - 202.9 1 2 0 0.0008 7 0 0 0 4.55E+08 3.17E+08 - - - 2.4108 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.16851.16851.2 0.00402 16-Sep R.GLFTGLTPR.L "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 960.5393 1.26 58690 16851 2 960.537882 481.2769 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3358.7 - 958566 - - - -1.4409 - 1.746 0.286 - 217.3 1 2 0 -0.0014 9 0 0 0 8.74E+07 6.93E+07 - - - 2.7653 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.16853.16853.2 0.141 14-Aug R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 8501.81 58691 16853 2 1000.561103 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3358.9 - 2.04E+09 - - - 1.769 - 1.936 0.282 - 235.4 1 2 0 0.0018 8 0 0 0 9.97E+11 1.17E+08 - - - 3.1157 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.16855.16855.2 0.000574 16-Nov K.LLC[160.03]GLLAER[166.11].L sp|P14174|MIF_HUMAN 1 1053.588 0.91 58692 16855 2 1053.58627 527.8013 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3359.1 - 3.03E+06 - - - -1.6619 - 1.997 0.256 - 391.6 1 2 0 -0.0018 9 0 0 0 1.02E+09 1.12E+09 - - - 2.9322 0.9877 230117_WJC_METTL3_WT_vs_EV_F07.16856.16856.2 0.0362 16-Jul R.YVANLFPYK[136.11].G "sp|Q15181|IPYR_HUMAN,sp|Q9H2U2|IPYR2_HUMAN,tr|D6RGV9|D6RGV9_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN,tr|D6RGI1|D6RGI1_HUMAN,tr|H0YAK2|H0YAK2_HUMAN" 7 1121.6001 2.44 58693 16856 2 1121.597709 561.8073 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 8.5 3359.3 - 902510 - - - -2.1157 - 1.326 0.239 - 141.7 1 2 0 -0.0024 9 0 0 0 1.36E+08 5.56E+07 - - - 1.6218 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.16857.16857.2 0.00116 16-Sep R.GLFTGLTPR[166.11].L "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 970.5475 1.26 58694 16857 2 970.547242 486.281 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3359.4 - 1.43E+06 - - - -0.3029 - 1.83 0.287 - 223.8 1 2 0 -0.0003 9 0 0 0 8.74E+07 6.93E+07 - - - 2.909 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.16862.16862.2 0.00111 16-Oct K.LLC[160.03]GLLAER.L sp|P14174|MIF_HUMAN 1 1043.5798 0.91 58697 16862 2 1043.578858 522.7972 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3360 - 6.34E+06 - - - -0.8557 - 2.021 0.389 - 335.2 1 2 0 -0.0009 9 0 0 0 1.02E+09 1.13E+09 - - - 3.9494 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.16863.16863.2 0.0575 12-Jul R.FVAELWK.D sp|P35580|MYH10_HUMAN 1 891.4854 0.66 58698 16863 2 891.486493 446.75 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3360.1 - 3.13E+06 - - - 1.1812 - 1.468 0.258 - 151.5 1 2 0 0.0011 7 0 0 0 1.19E+08 1.81E+08 - - - 2.1627 0.9929 230117_WJC_METTL3_WT_vs_EV_F07.16868.16868.2 1.17 12-Jun R.GFELTFK[136.11].T "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 848.4524 1.5 58703 16868 2 848.45299 425.2335 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3360.7 - 966337 - - - 0.7484 - 1.221 0.149 - 132.6 1 2 0 0.0006 7 0 0 0 1.02E+08 6.76E+07 - - - 0.774 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.16871.16871.2 0.00366 18-Jul K.APGLGLVLER.V "sp|Q9Y606|TRUA_HUMAN,tr|G8JLB3|G8JLB3_HUMAN,tr|F5H1S9|F5H1S9_HUMAN" 3 1023.6077 1.78 58704 16871 2 1023.607247 512.8111 tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3 6.05 3361.1 - 2.20E+06 - - - -0.423 - 1.453 0.361 - 114.6 1 2 0 -0.0004 10 0 0 0 5.79E+07 3.26E+07 - - - 2.7501 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.16873.16873.2 0.07 14-Jul K.LGPLAFYK[136.11].G "sp|Q9UBX3|DIC_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 915.5309 1.66 58706 16873 2 915.532781 458.7727 Mitochondrial dicarboxylate carrier OS=Homo sapiens OX=9606 GN=SLC25A10 PE=1 SV=2 8.59 3361.2 - 1.99E+06 - - - 2.0109 - 1.35 0.267 - 116.1 1 2 0 0.0018 8 0 0 0 7.51E+07 4.54E+07 - - - 1.9176 1 230117_WJC_METTL3_WT_vs_EV_F07.16874.16874.2 4.55E-05 18-Nov K.VYVIGSFVDK[136.11].S sp|Q7L0Y3|TM10C_HUMAN 1 1133.6212 0.78 58707 16874 2 1133.622854 567.8179 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3361.3 - 1.73E+06 - - - 1.4493 - 2.148 0.495 - 366.1 1 2 0 0.0016 10 0 0 0 4.89E+07 6.28E+07 - - - 4.8306 0.9947 230117_WJC_METTL3_WT_vs_EV_F07.16877.16877.2 0.499 12-Jun R.LTLLQLK.G sp|Q8NHP8|PLBL2_HUMAN 1 827.548 1.17 58710 16877 2 827.547738 414.7813 Putative phospholipase B-like 2 OS=Homo sapiens OX=9606 GN=PLBD2 PE=1 SV=2 8.75 3361.6 - 1.35E+06 - - - -0.3649 - 1.348 0.19 - 69.8 1 2 0 -0.0003 7 0 0 0 2.99E+07 2.56E+07 - - - 1.3904 1 230117_WJC_METTL3_WT_vs_EV_F07.16882.16882.2 9.62E-06 13/18 K.VYVIGSFVDK.S sp|Q7L0Y3|TM10C_HUMAN 1 1125.607 0.78 58713 16882 2 1125.610653 563.8108 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3362.2 - 1.64E+06 - - - 3.2356 - 2.623 0.4 - 632 1 2 0 0.0036 10 0 0 0 4.89E+07 6.28E+07 - - - 4.686 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.16883.16883.2 0.00175 16-Oct K.FLGELYNYR[166.11].M sp|Q9HAU5|RENT2_HUMAN 1 1183.5901 0.76 58714 16883 2 1183.59456 592.8023 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 6 3362.3 - 1.09E+06 - - - 3.7437 - 1.578 0.391 - 322.5 1 2 0 0.0044 9 0 0 0 1.41E+07 1.86E+07 - - - 3.2472 0.901 230117_WJC_METTL3_WT_vs_EV_F07.16888.16888.2 8.31 12-May R.FLPLNIR.N "sp|Q7Z6E9|RBBP6_HUMAN,tr|H3BSK8|H3BSK8_HUMAN,tr|A0A2R8Y880|A0A2R8Y880_HUMAN" 3 871.528 0.78 58717 16888 2 871.530122 436.7713 E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1 9.75 3362.9 - 2.19E+06 - - - 2.4658 - 1.097 0.01 - 65.3 4 2 0 0.0021 7 0 0 0 6.95E+07 8.97E+07 - - - -0.8614 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.16892.16892.2 0.0344 20-Oct K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.06 58719 16892 2 1245.769255 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3363.4 - 1.07E+06 - - - 0.6638 - 1.961 0.339 - 301.5 1 2 0 0.0008 11 0 0 0 3.95E+07 3.73E+07 - - - 3.3664 0.9314 230117_WJC_METTL3_WT_vs_EV_F07.16894.16894.2 0.828 12-Aug K.LDDLFLK.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 862.48 1 58721 16894 2 862.476649 432.2473 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3363.6 - 1.96E+06 - - - -3.9085 - 1.584 0.08 - 220.5 1 2 0 -0.0034 7 0 0 0 1.96E+08 1.95E+08 - - - 1.0882 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.16896.16896.2 0.00014 22-Sep R.VLIGNVQPGILR.F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1277.782 4.02 58723 16896 2 1277.784023 639.8983 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3363.9 - 509154 - - - 1.6176 - 2.018 0.473 - 327.7 1 2 0 0.0021 12 0 0 0 9.13E+06 2.27E+06 - - - 4.3813 0.9925 230117_WJC_METTL3_WT_vs_EV_F07.16901.16901.2 0.742 16-Jul R.VLIFSQMTK.M "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|F2Z2R5|F2Z2R5_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|A0A5F9ZHX5|A0A5F9ZHX5_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|K7EMY3|K7EMY3_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 25 1065.5893 2.28 58726 16901 2 1065.592151 533.8019 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.72 3364.4 - 1.14E+06 - - - 2.7196 - 1.431 0.125 - 111.6 1 2 0 0.0029 9 0 0 0 2.15E+07 9.45E+06 - - - 1.0001 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.16908.16908.2 0.0146 14-Sep R.ILELDQFK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1012.5684 1.03 58731 16908 2 1012.569665 507.2915 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3365.3 - 7.87E+06 - - - 1.2029 - 1.863 0.333 - 203.7 1 2 0 0.0012 8 0 0 0 4.14E+08 4.02E+08 - - - 3.3766 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.16909.16909.2 0.00491 14-Sep R.LYEFYLSK.C "sp|Q5VZL5|ZMYM4_HUMAN,tr|H7C1I7|H7C1I7_HUMAN" 2 1061.5433 1.23 58732 16909 2 1061.544309 531.779 Zinc finger MYM-type protein 4 OS=Homo sapiens OX=9606 GN=ZMYM4 PE=1 SV=1 6 3365.4 - 1.33E+06 - - - 0.9053 - 1.475 0.322 - 193.6 1 2 0 0.001 8 0 0 0 2.79E+07 2.26E+07 - - - 2.5912 0.9779 230117_WJC_METTL3_WT_vs_EV_F07.16910.16910.2 6.06 12-May K.LLLWSQR.M "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|E9PQ28|E9PQ28_HUMAN,tr|E9PKG0|E9PKG0_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 5 914.5338 0.68 58733 16910 2 914.535869 458.2742 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 9.75 3365.5 - 1.06E+06 - - - 2.2766 - 1.002 0.139 - 80.8 1 2 0 0.0021 7 0 0 0 3.31E+07 4.90E+07 - - - 0.0733 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.16914.16914.2 0.00362 12-Jul K.LMIWDTR[166.11].S "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 943.4825 1.76 58736 16914 2 943.484047 472.7485 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3365.9 - 7.64E+06 - - - 1.6471 - 1.466 0.354 - 279.5 1 2 0 0.0016 7 0 0 0 4.52E+08 2.56E+08 - - - 2.8672 0.9552 230117_WJC_METTL3_WT_vs_EV_F07.16917.16917.2 0.0016 16-Sep K.IDPEAFITR[166.11].H sp|Q92616|GCN1_HUMAN 1 1070.5636 1.09 58738 16917 2 1070.55993 536.2891 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3366.2 - 910783 - - - -3.4094 - 1.474 0.14 - 178.1 1 2 0 -0.0037 9 0 0 0 4.63E+07 4.23E+07 - - - 1.1963 0.9776 230117_WJC_METTL3_WT_vs_EV_F07.16918.16918.2 2.08 20-Nov R.ALDEGDIALLK.T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1156.634 2.73 58739 16918 2 1156.635399 579.3243 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 3366.3 - 759135 - - - 1.2493 - 1.028 0.11 - 126.9 1 2 0 0.0014 11 0 0 0 2.00E+07 7.34E+06 - - - -0.0723 1 230117_WJC_METTL3_WT_vs_EV_F07.16919.16919.2 0.000346 20-Dec R.ALDEGDIALLK[136.11].T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1164.6482 2.66 58740 16919 2 1164.647547 583.3314 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 3366.5 - 405695 - - - -0.5212 - 2.37 0.453 - 287.3 1 2 0 -0.0006 11 0 0 0 1.95E+07 7.34E+06 - - - 4.721 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.16924.16924.2 0.00214 14-Aug R.VWDISGLR[166.11].K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 954.5162 2.92 58743 16924 2 954.516673 478.2654 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3367.1 - 1.38E+06 - - - 0.4578 - 1.83 0.164 - 210.2 1 2 0 0.0004 8 0 0 0 1.21E+08 4.13E+07 - - - 2.0748 1 230117_WJC_METTL3_WT_vs_EV_F07.16925.16925.2 0.000207 18-Nov R.FVNVVPTFGK.K "sp|P62861|RS30_HUMAN,tr|E9PR30|E9PR30_HUMAN" 2 1106.6124 1.12 58744 16925 2 1106.615044 554.3135 40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1 8.75 3367.3 - 852482 - - - 2.3613 - 2.198 0.541 - 370.3 1 2 0 0.0026 10 0 0 0 2.51E+07 2.24E+07 - - - 5.2343 0.9547 230117_WJC_METTL3_WT_vs_EV_F07.16927.16927.2 0.112 16-Jul K.YFLGQSVLR.S "sp|Q9Y255|PRLD1_HUMAN,tr|D6REW1|D6REW1_HUMAN,tr|D6RC47|D6RC47_HUMAN" 3 1081.592 1.06 58746 16927 2 1081.58975 541.8033 "PRELI domain-containing protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=PRELID1 PE=1 SV=1" 8.75 3367.4 - 631685 - - - -2.108 - 1.289 0.128 - 96.1 2 2 0 -0.0023 9 0 0 0 1.70E+07 1.59E+07 - - - 0.5857 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.16932.16932.2 0.157 20-Oct R.ALAAQLPVLPR.S "sp|Q96GK7|FAH2A_HUMAN,tr|C9JGM0|C9JGM0_HUMAN" 2 1147.7077 2.46 58749 16932 2 1147.708885 574.8611 Fumarylacetoacetate hydrolase domain-containing protein 2A OS=Homo sapiens OX=9606 GN=FAHD2A PE=1 SV=1 9.79 3368.1 - 493616 - - - 1.0081 - 1.978 0.329 - 274.8 1 2 0 0.0012 11 0 0 0 1.07E+07 4.37E+06 - - - 3.3158 0.9849 230117_WJC_METTL3_WT_vs_EV_F07.16934.16934.2 0.258 20-Oct K.LLAAFPGVTPR.V "sp|Q9Y2I1|NISCH_HUMAN,tr|C9J715|C9J715_HUMAN" 2 1140.6655 3.11 58751 16934 2 1140.662116 571.34 Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3 9.75 3368.3 - 361810 - - - -2.9921 - 1.714 0.193 - 255.1 1 2 0 -0.0034 11 0 0 0 1.55E+07 4.97E+06 - - - 1.9231 0.9652 230117_WJC_METTL3_WT_vs_EV_F07.16939.16939.2 0.0138 14-Jul R.VWDISGLR.K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 944.508 2.93 58754 16939 2 944.513257 473.2613 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3368.9 - 6.96E+06 - - - 5.6019 - 1.754 0.073 - 237.3 1 2 0 0.0053 8 0 0 0 1.21E+08 4.14E+07 - - - 1.2732 0.9955 230117_WJC_METTL3_WT_vs_EV_F07.16944.16944.2 0.093 20-Aug R.LYPEGLAQLAR[166.11].A "sp|P61421|VA0D1_HUMAN,tr|J3QL14|J3QL14_HUMAN,tr|F5GYQ1|F5GYQ1_HUMAN,tr|R4GN72|R4GN72_HUMAN" 4 1239.6851 1.25 58759 16944 2 1239.689141 620.8498 V-type proton ATPase subunit d 1 OS=Homo sapiens OX=9606 GN=ATP6V0D1 PE=1 SV=1 6 3369.4 - 256106 - - - 3.2662 - 1.393 0.237 - 142.8 1 2 0 0.004 11 0 0 0 1.65E+07 1.32E+07 - - - 1.6869 0.998 230117_WJC_METTL3_WT_vs_EV_F07.16948.16948.2 0.985 12-Aug K.LDDLFLK[136.11].R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 870.4942 1 58761 16948 2 870.495565 436.2544 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3370 - 7.72E+06 - - - 1.5451 - 1.844 0.101 - 205.5 1 2 0 0.0013 7 0 0 0 1.90E+08 1.90E+08 - - - 1.7255 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.16950.16950.2 0.00916 14-Sep R.ILELDQFK.G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1004.5542 0.9 58763 16950 2 1004.556506 503.2844 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3370.1 - 2.05E+07 - - - 2.2488 - 1.965 0.385 - 227 1 2 0 0.0023 8 0 0 0 3.52E+08 3.90E+08 - - - 3.9212 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.16951.16951.2 0.159 12-Jul R.IPTAWFR.E "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN" 2 889.481 1.05 58764 16951 2 889.482965 445.7478 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 9.75 3370.1 - 1.81E+06 - - - 2.1833 - 1.222 0.253 - 148.7 1 2 0 0.0019 7 0 0 0 1.37E+08 1.30E+08 - - - 1.5443 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.16952.16952.2 1.19E-05 18-Sep K.IVAFENAFER.L sp|O60763|USO1_HUMAN 1 1194.6033 0.89 58765 16952 2 1194.604027 598.3089 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 3370.2 - 554755 - - - 0.5893 - 2.123 0.302 - 190.8 1 2 0 0.0007 10 0 0 0 1.00E+07 1.12E+07 - - - 3.3727 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.16957.16957.2 0.0334 14-Oct K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 0.79 58768 16957 2 988.573739 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3370.9 - 2.90E+06 - - - 3.2097 - 1.741 0.316 - 409.1 1 2 0 0.0032 8 0 0 0 5.42E+09 6.85E+09 - - - 3.0462 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.16958.16958.2 0.0242 14-Jul K.LEPDILLR.A "sp|Q01433|AMPD2_HUMAN,tr|A0A7P0TB79|A0A7P0TB79_HUMAN,tr|A0A590UK85|A0A590UK85_HUMAN,tr|A0A5F9UK94|A0A5F9UK94_HUMAN,tr|E9PJF6|E9PJF6_HUMAN,tr|A0A590UJX5|A0A590UJX5_HUMAN,tr|H0Y360|H0Y360_HUMAN,tr|A0A7P0Z4H6|A0A7P0Z4H6_HUMAN,tr|E9PIJ1|E9PIJ1_HUMAN,tr|H0YF16|H0YF16_HUMAN,tr|A0A804CCZ3|A0A804CCZ3_HUMAN" 11 967.5702 2.74 58769 16958 2 967.571938 484.7924 AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2 4.37 3371 - 514875 - - - 1.7632 - 1.49 0.245 - 153.1 1 2 0 0.0017 8 0 0 0 2.14E+07 7.83E+06 - - - 2.0527 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.16959.16959.2 0.00156 12-Aug K.FIDPFC[160.03]K.L sp|Q14684|RRP1B_HUMAN 1 925.4368 4.75 58770 16959 2 925.439449 463.7257 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.83 3371.1 - 2.22E+06 - - - 2.8894 - 1.286 0.34 - 174.8 1 2 0 0.0027 7 0 0 0 6.24E+07 1.31E+07 - - - 2.3484 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.16973.16973.2 0.00218 16-Aug R.ATLNAFLYR[166.11].T "sp|Q5T2N8|ATD3C_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 3 1077.5847 1.33 58782 16973 2 1077.585452 539.7996 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 8.79 3372.7 - 526279 - - - 0.7443 - 1.982 0.351 - 190.7 1 2 0 0.0008 9 0 0 0 6.53E+07 4.89E+07 - - - 3.6124 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.16974.16974.2 0.295 20-Aug K.LLAAFPGVTPR[166.11].V "sp|Q9Y2I1|NISCH_HUMAN,tr|C9J715|C9J715_HUMAN" 2 1150.6738 3.16 58783 16974 2 1150.675 576.3442 Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3 9.75 3372.8 - 126416 - - - 1.0437 - 1.703 0.176 - 151.6 1 2 0 0.0012 11 0 0 0 1.57E+07 4.97E+06 - - - 1.7808 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.16977.16977.2 0.0142 14-Aug K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 0.79 58784 16977 2 998.581316 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3373.2 - 6.71E+07 - - - 2.4835 - 1.684 0.332 - 314.2 1 2 0 0.0025 8 0 0 0 5.42E+09 6.85E+09 - - - 3.0642 0.9955 230117_WJC_METTL3_WT_vs_EV_F07.16978.16978.2 1.06 14-Jun R.DILLQGLK[136.11].A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 906.563 0.8 58785 16978 2 906.564768 454.2888 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3373.3 - 1.79E+06 - - - 1.9855 - 1.327 0.167 - 96.9 1 2 0 0.0018 8 0 0 0 2.32E+07 2.91E+07 - - - 1.1272 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.16979.16979.2 0.0127 16-Aug R.EPGEFALLR[166.11].S sp|O43505|B4GA1_HUMAN 1 1040.553 3.53 58786 16979 2 1040.555383 521.2838 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 4.53 3373.3 - 2.37E+06 - - - 2.2757 - 1.67 0.378 - 363.6 1 2 0 0.0024 9 0 0 0 3.58E+08 1.02E+08 - - - 3.3158 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.16981.16981.2 0.000181 18-Oct K.IVAFENAFER[166.11].L sp|O60763|USO1_HUMAN 1 1204.6116 0.89 58788 16981 2 1204.615961 603.3131 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 3373.5 - 768755 - - - 3.6261 - 1.91 0.494 - 279.6 1 2 0 0.0044 10 0 0 0 1.00E+07 1.12E+07 - - - 4.4946 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.16988.16988.2 0.187 14-Oct R.DILLQGLK.A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 898.5488 0.8 58793 16988 2 898.55072 450.2817 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3374.4 - 1.43E+06 - - - 2.1724 - 1.8 0.169 - 308.8 1 2 0 0.002 8 0 0 0 2.33E+07 2.91E+07 - - - 2.0614 0.9932 230117_WJC_METTL3_WT_vs_EV_F07.16993.16993.2 0.158 16-Oct K.IDVGDVILK.V sp|Q12923|PTN13_HUMAN 1 970.5699 4.39 58798 16993 2 970.57533 486.2922 Tyrosine-protein phosphatase non-receptor type 13 OS=Homo sapiens OX=9606 GN=PTPN13 PE=1 SV=2 4.21 3374.8 - 398949 - - - 5.5967 - 1.849 0.279 - 147.8 1 2 0 0.0054 9 0 0 0 1.74E+07 3.96E+06 - - - 2.8782 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.16994.16994.2 0.0185 18-Sep K.IEDMAVSLIR.E sp|Q15776|ZKSC8_HUMAN 1 1145.6114 0.89 58799 16994 2 1145.614629 573.813 Zinc finger protein with KRAB and SCAN domains 8 OS=Homo sapiens OX=9606 GN=ZKSCAN8 PE=1 SV=2 4.37 3375 - 379065 - - - 2.7793 - 2.018 0.3 - 214.4 1 2 0 0.0032 10 0 0 0 5.34E+06 5.98E+06 - - - 3.2156 0.9492 230117_WJC_METTL3_WT_vs_EV_F07.16999.16999.2 1.81 12-Apr K.VLLPFTR.A sp|Q8TEM1|PO210_HUMAN 1 844.5171 2.15 58802 16999 2 844.517548 423.2658 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 9.72 3375.6 - 1.12E+06 - - - 0.5613 - 0.971 0.119 - 63 6 2 0 0.0005 7 0 0 0 6.39E+07 2.98E+07 - - - -0.5211 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.17002.17002.2 0.00569 18-Aug R.VIAIDIDPVK[136.11].L sp|Q96RS0|TGS1_HUMAN 1 1089.6525 2.16 58805 17002 2 1089.651175 545.8335 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 4.21 3375.9 - 1.29E+06 - - - -1.2261 - 1.572 0.279 - 133.1 1 2 0 -0.0013 10 0 0 0 2.87E+07 1.33E+07 - - - 2.3639 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17004.17004.2 0.00851 14-Aug R.LELSVLYK.E "sp|Q96FW1|OTUB1_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 5 963.5641 2.47 58807 17004 2 963.565565 482.7893 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 6 3376.2 - 964374 - - - 1.537 - 1.816 0.26 - 157 1 2 0 0.0015 8 0 0 0 2.16E+07 8.74E+06 - - - 2.7603 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.17006.17006.2 0.163 18-Sep R.LLLNNDNLLR[166.11].E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1206.696 1.47 58809 17006 2 1206.696174 604.3553 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3376.4 - 630166 - - - 0.1517 - 1.815 0.224 - 217.3 1 2 0 0.0002 10 0 0 0 2.76E+08 1.87E+08 - - - 2.3593 0.9918 230117_WJC_METTL3_WT_vs_EV_F07.17007.17007.2 0.199 22-Sep -.MVPPVQVSPLIK[136.11].L sp|P56385|ATP5I_HUMAN 1 1314.7825 1.25 58810 17007 2 1314.781256 658.3985 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3376.6 - 601894 - - - -0.931 - 1.573 0.148 - 110.8 1 2 0 -0.0012 12 0 0 0 2.51E+07 2.00E+07 - - - 1.3256 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17008.17008.2 0.00227 18-Sep K.IEDMAVSLIR[166.11].E sp|Q15776|ZKSC8_HUMAN 1 1155.6197 1.09 58811 17008 2 1155.621305 578.8171 Zinc finger protein with KRAB and SCAN domains 8 OS=Homo sapiens OX=9606 GN=ZKSCAN8 PE=1 SV=2 4.37 3376.7 - 557502 - - - 1.3759 - 1.938 0.345 - 181.9 1 2 0 0.0016 10 0 0 0 5.16E+06 4.75E+06 - - - 3.4356 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.17015.17015.2 0.149 12-Jul R.LLQLWEK[136.11].N "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 936.5524 1.32 58815 17015 2 936.554661 469.2835 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 6 3377.5 - 1.96E+06 - - - 2.411 - 1.472 0.188 - 125.4 1 2 0 0.0023 7 0 0 0 9.06E+07 6.88E+07 - - - 1.6539 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17016.17016.2 0.0327 18-Aug R.LLLNNDNLLR.E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1196.6877 1.47 58816 17016 2 1196.690296 599.3511 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3377.7 - 902833 - - - 2.1518 - 1.931 0.355 - 195 1 2 0 0.0026 10 0 0 0 2.76E+08 1.87E+08 - - - 3.499 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17018.17018.2 0.000523 20-Sep R.LYPEGLAQLAR.A "sp|P61421|VA0D1_HUMAN,tr|J3QL14|J3QL14_HUMAN,tr|F5GYQ1|F5GYQ1_HUMAN,tr|R4GN72|R4GN72_HUMAN" 4 1229.6768 1.25 58818 17018 2 1229.678735 615.8457 V-type proton ATPase subunit d 1 OS=Homo sapiens OX=9606 GN=ATP6V0D1 PE=1 SV=1 6 3377.9 - 479928 - - - 1.5557 - 1.559 0.406 - 302.5 1 2 0 0.0019 11 0 0 0 1.65E+07 1.32E+07 - - - 3.2404 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17020.17020.2 0.000688 18-Sep K.AVFVPDIYSR.T sp|O94874|UFL1_HUMAN 1 1165.6132 2.03 58820 17020 2 1165.613444 583.8139 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.88 3378.1 - 405248 - - - 0.2445 - 1.933 0.403 - 311 1 2 0 0.0003 10 0 0 0 1.78E+07 8.80E+06 - - - 3.8571 0.9387 230117_WJC_METTL3_WT_vs_EV_F07.17025.17025.2 3.72 14-Jun R.ILDLGFEK[136.11].D "sp|Q9H8H2|DDX31_HUMAN,tr|F8WAJ0|F8WAJ0_HUMAN" 2 941.5313 1.87 58823 17025 2 941.537099 471.7729 Probable ATP-dependent RNA helicase DDX31 OS=Homo sapiens OX=9606 GN=DDX31 PE=1 SV=2 4.37 3378.6 - 660169 - - - 6.123 - 1.405 0.138 - 61.8 1 2 0 0.0058 8 0 0 0 2.03E+07 1.09E+07 - - - 1.084 0.999 230117_WJC_METTL3_WT_vs_EV_F07.17028.17028.2 0.0123 12-Aug K.TDFGIFR.M "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 10 854.4287 1.47 58824 17028 2 854.428876 428.2216 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.5 3379 - 1.15E+06 - - - 0.261 - 1.389 0.346 - 282.9 1 2 0 0.0002 7 0 0 0 2.60E+07 1.77E+07 - - - 2.6376 0.9133 230117_WJC_METTL3_WT_vs_EV_F07.17029.17029.2 8.78 12-Jun R.IQLFLAR.L "sp|Q96FV9|THOC1_HUMAN,tr|A0A087WWS1|A0A087WWS1_HUMAN,tr|A0A087WY84|A0A087WY84_HUMAN,tr|J3KT14|J3KT14_HUMAN" 4 859.528 0.44 58825 17029 2 859.530427 430.7713 THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1 9.75 3379.2 - 516044 - - - 2.8551 - 1.187 0.017 - 106.2 6 2 0 0.0025 7 0 0 0 9.57E+06 2.17E+07 - - - -0.6386 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.17031.17031.2 0.00249 14-Jul R.LMGDYLLR.G "sp|O60232|ZNRD2_HUMAN,tr|H0YEK1|H0YEK1_HUMAN,tr|E9PK41|E9PK41_HUMAN,tr|H0YEB6|H0YEB6_HUMAN" 4 979.5161 9.17 58827 17031 2 979.519941 490.7653 Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1 5.84 3379.4 - 753884 - - - 3.9336 - 1.485 0.405 - 133.1 1 2 0 0.0039 8 0 0 0 3.41E+07 3.72E+06 - - - 3.2237 1 230117_WJC_METTL3_WT_vs_EV_F07.17032.17032.2 2.67E-07 26-Dec R.EAGNINQSLLTLGR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1494.803 0.36 58828 17032 2 1494.801984 748.4088 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.1 3379.5 - 270338 - - - -0.6636 - 2.437 0.565 - 405.7 1 2 0 -0.001 14 0 0 0 8.23E+05 2.31E+06 - - - 5.4491 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17038.17038.2 0.0787 18-Sep K.AVFVPDIYSR[166.11].T sp|O94874|UFL1_HUMAN 1 1175.6214 2.05 58831 17038 2 1175.622711 588.818 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.88 3380.4 - 499310 - - - 1.0905 - 1.808 0.361 - 279.9 1 2 0 0.0013 10 0 0 0 1.80E+07 8.80E+06 - - - 3.36 0.9914 230117_WJC_METTL3_WT_vs_EV_F07.17042.17042.2 1.11 14-Jun K.YVVGLIIK.T "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 903.5793 1.39 58834 17042 2 903.579723 452.7969 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3380.8 - 4.01E+06 - - - 0.4239 - 0.931 0.255 - 98.6 1 2 0 0.0004 8 0 0 0 4.49E+07 3.24E+07 - - - 0.7087 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17046.17046.2 0.00242 13/22 K.ALLTPVAIAAGR.K sp|P00390|GSHR_HUMAN 1 1151.7026 3.01 58836 17046 2 1151.706216 576.8586 "Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2" 9.79 3381.3 - 257743 - - - 3.1024 - 2.535 0.369 - 429.1 1 2 0 0.0036 12 0 0 0 3.94E+07 1.31E+07 - - - 4.2128 0.9914 230117_WJC_METTL3_WT_vs_EV_F07.17051.17051.2 2.3 18-Oct R.LGLSTLGELK.Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1029.607 2.6 58838 17051 2 1029.60917 515.8108 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3381.9 - 2.51E+06 - - - 2.0969 - 1.407 0.092 - 179 1 2 0 0.0022 10 0 0 0 2.47E+08 9.50E+07 - - - 0.673 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.17053.17053.2 0.0135 16-Aug K.LFSELPLAK.K "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1016.5906 1.16 58840 17053 2 1016.590616 509.3026 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 6 3382.1 - 3.46E+06 - - - -0.0167 - 1.53 0.36 - 180.6 1 2 0 0 9 0 0 0 1.26E+08 1.09E+08 - - - 2.9303 1 230117_WJC_METTL3_WT_vs_EV_F07.17054.17054.2 6.49E-06 24-Oct R.ILGVGPDDPDLVR.A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1364.73 3.1 58841 17054 2 1364.732258 683.3723 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3382.3 - 348289 - - - 1.6692 - 2.195 0.536 - 313.3 1 2 0 0.0023 13 0 0 0 5.81E+06 1.87E+06 - - - 5.0169 0.9947 230117_WJC_METTL3_WT_vs_EV_F07.17058.17058.2 2.06 12-Jul K.LLLDMYK.S "sp|O75150|BRE1B_HUMAN,tr|H3BP71|H3BP71_HUMAN" 2 894.4885 0.68 58842 17058 2 894.492704 448.2515 E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5 5.83 3382.8 - 330108 - - - 4.7267 - 1.446 0.307 - 131.9 1 2 0 0.0042 7 0 0 0 9.35E+06 1.38E+07 - - - 2.4757 0.9565 230117_WJC_METTL3_WT_vs_EV_F07.17071.17071.2 0.0603 14-Jul R.VFPMPLPR.K "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|C9JZP1|C9JZP1_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 4 955.5313 1.97 58853 17071 2 955.53843 478.7729 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 9.72 3384.4 - 828567 - - - 7.4158 - 1.541 0.232 - 204.6 1 2 0 0.0071 8 0 0 0 3.02E+07 1.54E+07 - - - 2.0565 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.17072.17072.2 1.70E-05 18-Aug R.LLYEALVDC[160.03]K[136.11].K "sp|Q7L2H7|EIF3M_HUMAN,tr|J3KNJ2|J3KNJ2_HUMAN,tr|E9PRY0|E9PRY0_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 4 1230.641 0.68 58854 17072 2 1230.639564 616.3278 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 4.37 3384.5 - 283735 - - - -1.1352 - 1.824 0.497 - 200.1 1 2 0 -0.0014 10 0 0 0 2.90E+06 4.23E+06 - - - 4.3891 0.9883 230117_WJC_METTL3_WT_vs_EV_F07.17079.17079.2 0.0173 14-Nov K.MFAEIMMK[136.11].L "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1007.4734 0.63 58859 17079 2 1007.480935 504.744 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 5.75 3385.3 - 833045 - - - 7.5119 - 2.17 0.333 - 361.8 1 2 0 0.0076 8 0 0 0 9.17E+06 1.45E+07 - - - 3.8347 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17080.17080.2 0.00793 18-Oct R.LGLSTLGELK[136.11].Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1037.6212 2.6 58860 17080 2 1037.6233 519.8179 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3385.4 - 2.86E+06 - - - 2.0133 - 2.103 0.355 - 169.7 1 2 0 0.0021 10 0 0 0 2.47E+08 9.50E+07 - - - 3.7373 0.9965 230117_WJC_METTL3_WT_vs_EV_F07.17081.17081.2 0.047 12-Jul R.VPFSLLR.G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 830.5014 1.07 58861 17081 2 830.50345 416.258 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3385.5 - 1.50E+06 - - - 2.4395 - 1.337 0.206 - 172.7 1 2 0 0.002 7 0 0 0 7.10E+07 6.64E+07 - - - 1.4821 0.9938 230117_WJC_METTL3_WT_vs_EV_F07.17082.17082.2 0.191 12-Jul R.VPFSLLR[166.11].G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 840.5097 1.03 58862 17082 2 840.511519 421.2621 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3385.6 - 1.46E+06 - - - 2.1713 - 1.29 0.147 - 220.4 1 2 0 0.0018 7 0 0 0 7.11E+07 6.91E+07 - - - 0.933 0.999 230117_WJC_METTL3_WT_vs_EV_F07.17086.17086.2 1.78E-05 24-Oct R.ILGVGPDDPDLVR[166.11].A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1374.7383 3.1 58866 17086 2 1374.743967 688.3764 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3386.1 - 168766 - - - 4.1586 - 2.086 0.494 - 333.1 1 2 0 0.0057 13 0 0 0 5.81E+06 1.87E+06 - - - 4.5749 0.9966 230117_WJC_METTL3_WT_vs_EV_F07.17091.17091.2 0.0643 16-Jul R.LVSLYFDTK.R "sp|O00231|PSD11_HUMAN,tr|J3QRY4|J3QRY4_HUMAN,tr|J3KSW3|J3KSW3_HUMAN" 3 1084.5805 1.82 58869 17091 2 1084.581732 543.2975 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 5.83 3386.8 - 2.39E+06 - - - 1.171 - 1.356 0.184 - 96.1 1 2 0 0.0013 9 0 0 0 3.58E+07 1.97E+07 - - - 1.2807 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.17093.17093.2 0.00216 14-Aug K.AGPIWDLR.L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 926.4974 0.98 58871 17093 2 926.500544 464.256 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3387 - 2.66E+06 - - - 3.3923 - 1.359 0.362 - 245.8 1 2 0 0.0031 8 0 0 0 5.22E+08 5.34E+08 - - - 2.6389 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.17095.17095.2 3.52E-05 16-Sep R.ELLTEFGYK[136.11].G sp|P49411|EFTU_HUMAN 1 1106.5739 2.38 58873 17095 2 1106.579018 554.2942 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.53 3387.2 - 733188 - - - 4.6007 - 1.887 0.487 - 240.3 1 2 0 0.0051 9 0 0 0 3.67E+07 1.54E+07 - - - 4.4734 1 230117_WJC_METTL3_WT_vs_EV_F07.17096.17096.2 0.000662 18-Dec K.VFEVMLATDR.S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1179.5958 1.59 58874 17096 2 1179.599667 590.8052 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3387.4 - 433815 - - - 3.2825 - 2.31 0.463 - 700.4 1 2 0 0.0039 10 0 0 0 1.02E+07 6.44E+06 - - - 4.7965 1 230117_WJC_METTL3_WT_vs_EV_F07.17097.17097.2 4.78E-05 18-Nov K.VTDAIVLLDR.E "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1113.6394 3.05 58875 17097 2 1113.642985 557.827 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.21 3387.5 - 405202 - - - 3.2425 - 2.497 0.473 - 450 1 2 0 0.0036 10 0 0 0 1.54E+08 5.03E+07 - - - 5.0877 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17098.17098.2 0.00202 18-Oct K.VFEVMLATDR[166.11].S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1189.6041 1.58 58876 17098 2 1189.604409 595.8093 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3387.6 - 289783 - - - 0.2892 - 2.171 0.401 - 439.4 1 2 0 0.0003 10 0 0 0 1.06E+07 6.67E+06 - - - 4.1665 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.17103.17103.2 0.0213 20-Sep K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 -1 58880 17103 2 1235.763464 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3388.3 - 625420 - - - 2.6753 - 1.939 0.323 - 231.3 1 2 0 0.0033 11 0 0 0 0.00E+00 0.00E+00 - - - 3.217 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17107.17107.2 0.0418 14-Aug K.AGPIWDLR[166.11].L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 936.5057 0.98 58883 17107 2 936.50747 469.2601 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3388.6 - 3.36E+06 - - - 1.921 - 1.585 0.343 - 288.6 1 2 0 0.0018 8 0 0 0 5.22E+08 5.33E+08 - - - 2.9629 1 230117_WJC_METTL3_WT_vs_EV_F07.17111.17111.2 2.20E-05 18-Dec K.VTDAIVLLDR[166.11].E "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1123.6476 3.05 58887 17111 2 1123.649465 562.8311 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.21 3388.9 - 280523 - - - 1.6206 - 2.519 0.431 - 550.5 1 2 0 0.0018 10 0 0 0 1.53E+08 5.03E+07 - - - 4.8026 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17116.17116.2 0.0286 14-Aug R.LWDLVAGK.T "sp|O43660|PLRG1_HUMAN,tr|H0YA24|H0YA24_HUMAN" 2 900.5069 0.98 58891 17116 2 900.507571 451.2607 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 5.84 3389.6 - 666133 - - - 0.7418 - 1.658 0.338 - 180.7 1 2 0 0.0007 8 0 0 0 8.63E+07 8.77E+07 - - - 3.0622 0.964 230117_WJC_METTL3_WT_vs_EV_F07.17118.17118.2 0.000426 22-Jul R.IINEPTAAAIAY.G "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 16 1245.6605 - 58892 17118 2 1245.663142 623.8375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4 3389.8 - 2.03E+06 - - - 2.1178 - 1.591 0.444 - 110.5 1 1 0 0.0026 12 0 0 0 - - - - - 3.5414 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.17119.17119.2 0.00868 14-Jul K.MFGMVLEK[136.11].L sp|P55060|XPO2_HUMAN 1 961.4856 2.45 58893 17119 2 961.486948 481.7501 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.75 3389.8 - 1.48E+06 - - - 1.3542 - 1.329 0.298 - 130.9 1 2 0 0.0013 8 0 0 0 6.30E+07 2.57E+07 - - - 2.0994 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17132.17132.2 0.000241 14-Sep K.VDLVLLGK[136.11].Q sp|P38117|ETFB_HUMAN 1 863.5572 2.06 58904 17132 2 863.558717 432.7859 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3391.2 - 3.01E+06 - - - 1.81 - 1.871 0.421 - 268 1 2 0 0.0016 8 0 0 0 1.34E+08 6.49E+07 - - - 4.0394 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17134.17134.2 21.9 16-Nov K.R[166.11]VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1057.7239 1.26 58906 17134 2 1057.725685 529.8692 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3391.3 - 3.28E+06 - - - 1.7122 - 1.905 0.317 - 225.3 1 2 0 0.0018 9 0 0 0 2.19E+08 1.74E+08 - - - 3.2463 0.9693 230117_WJC_METTL3_WT_vs_EV_F07.17137.17137.2 0.000203 14-Sep K.PFYPALIR.Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 975.5542 0.81 58909 17137 2 975.555976 488.7844 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.18 3391.6 - 508645 - - - 1.8328 - 1.626 0.428 - 213.1 1 1 0 0.0018 8 0 0 0 8.37E+07 1.04E+08 - - - 3.6678 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.17143.17143.2 0.0113 12-Aug R.DGFGFIK.C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 782.3963 2 58913 17143 2 782.397557 392.2054 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3392.4 - 751006 - - - 1.6194 - 1.382 0.26 - 244.4 1 2 0 0.0013 7 0 0 0 9.28E+07 4.64E+07 - - - 1.9861 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.17145.17145.2 0.0574 14-Sep K.VDLVLLGK.Q sp|P38117|ETFB_HUMAN 1 855.543 1.83 58915 17145 2 855.545883 428.7788 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3392.7 - 1.75E+06 - - - 3.4236 - 1.988 0.273 - 310 1 2 0 0.0029 8 0 0 0 1.08E+08 5.89E+07 - - - 3.1288 0.8487 230117_WJC_METTL3_WT_vs_EV_F07.17146.17146.2 7.45E-05 14-Sep K.PFYPALIR[166.11].Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 985.5625 0.81 58916 17146 2 985.56734 493.7885 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.18 3392.8 - 861880 - - - 4.9535 - 1.928 0.392 - 359.5 1 1 0 0.0049 8 0 0 0 8.41E+07 1.04E+08 - - - 3.9147 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.17148.17148.2 0.000988 20-Sep R.IDGLAALSMDR[166.11].T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1170.5942 1.72 58918 17148 2 1170.59146 586.3044 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3393.1 - 171232 - - - -2.3646 - 2.023 0.389 - 179 1 2 0 -0.0028 11 0 0 0 1.53E+07 8.90E+06 - - - 3.8193 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17155.17155.2 0.0614 13/16 K.RVLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1037.7073 1.26 58923 17155 2 1037.708593 519.8609 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3394 - 3.92E+06 - - - 1.2133 - 2.054 0.331 - 288.4 1 2 0 0.0013 9 0 0 0 2.18E+08 1.73E+08 - - - 3.5678 0.9966 230117_WJC_METTL3_WT_vs_EV_F07.17156.17156.2 0.124 12-Jun R.DGFGFIK[136.11].C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 790.4105 2.02 58924 17156 2 790.411322 396.2125 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3394.1 - 2.25E+06 - - - 1.0526 - 1.175 0.236 - 135.5 1 2 0 0.0008 7 0 0 0 9.27E+07 4.59E+07 - - - 1.2948 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.17161.17161.2 0.0183 20-May R.IDGLAALSMDR.T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1160.586 1.28 58927 17161 2 1160.587434 581.3003 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3394.6 - 821278 - - - 1.2718 - 1.605 0.215 - 52.2 3 2 0 0.0015 11 0 0 0 1.55E+07 1.22E+07 - - - 1.6953 0.9953 230117_WJC_METTL3_WT_vs_EV_F07.17162.17162.2 0.00181 22-Dec R.AAVLFATDIAAR[166.11].G "sp|Q13206|DDX10_HUMAN,tr|A0A3B3ISR7|A0A3B3ISR7_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 3 1227.6851 0.82 58928 17162 2 1227.692495 614.8498 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 5.88 3394.8 - 218015 - - - 6.03 - 2.124 0.389 - 334.4 1 2 0 0.0074 12 0 0 0 4.90E+06 6.01E+06 - - - 3.8939 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17168.17168.2 1.24E-05 18-Aug R.FFNYVPSGIR[166.11].C "sp|Q969X6|UTP4_HUMAN,tr|H3BPD7|H3BPD7_HUMAN" 2 1208.6218 1.44 58932 17168 2 1208.625094 605.3182 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 8.75 3395.5 - 1.33E+06 - - - 2.7552 - 1.73 0.432 - 204.3 1 2 0 0.0033 10 0 0 0 2.40E+07 1.66E+07 - - - 3.7607 0.9738 230117_WJC_METTL3_WT_vs_EV_F07.17171.17171.2 0.229 14-Aug R.LPLAFAYR[166.11].E "sp|O14578|CTRO_HUMAN,tr|A0A7I2V692|A0A7I2V692_HUMAN,tr|H7BYJ3|H7BYJ3_HUMAN,tr|A0A7I2V365|A0A7I2V365_HUMAN,tr|A0A7I2V4H7|A0A7I2V4H7_HUMAN,tr|A0A7I2V4A6|A0A7I2V4A6_HUMAN,tr|A0A7I2V4I0|A0A7I2V4I0_HUMAN" 7 959.5468 1.46 58933 17171 2 959.552723 480.7807 Citron Rho-interacting kinase OS=Homo sapiens OX=9606 GN=CIT PE=1 SV=2 8.75 3395.9 - 1.03E+06 - - - 6.1644 - 1.731 0.156 - 129.3 1 2 0 0.0059 8 0 0 0 2.50E+07 1.72E+07 - - - 1.8462 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17172.17172.2 0.000843 18-Oct R.LVLSTFSNIR.E sp|Q8WVV4|POF1B_HUMAN 1 1148.6554 999 58934 17172 2 1148.659391 575.335 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 9.75 3396.1 - 461721 - - - 3.5102 - 1.962 0.441 - 230.8 1 2 0 0.004 10 0 0 0 1.09E+07 0.00E+00 - - - 4.1782 0.9575 230117_WJC_METTL3_WT_vs_EV_F07.17176.17176.2 7.29 14-Jun K.IMLAIITK.M "sp|P78412|IRX6_HUMAN,sp|P78414|IRX1_HUMAN,sp|P78413|IRX4_HUMAN,sp|Q9BZI1|IRX2_HUMAN,sp|P78411|IRX5_HUMAN,sp|P78415|IRX3_HUMAN,tr|D6RAS8|D6RAS8_HUMAN" 7 901.5671 0.67 58936 17176 2 901.568794 451.7908 Iroquois-class homeodomain protein IRX-6 OS=Homo sapiens OX=9606 GN=IRX6 PE=1 SV=3 8.75 3396.6 - 343453 - - - 1.9222 - 1.051 0.05 - 65.5 1 2 0 0.0017 8 0 0 0 7.03E+06 1.06E+07 - - - -0.4402 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.17183.17183.2 0.615 18-Sep R.LINLVGESLR[166.11].L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1122.6636 3.42 58941 17183 2 1122.666688 562.3391 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6 3397.4 - 1.78E+06 - - - 2.7248 - 1.979 0.186 - 228.6 1 2 0 0.0031 10 0 0 0 1.53E+08 4.46E+07 - - - 2.3192 0.9904 230117_WJC_METTL3_WT_vs_EV_F07.17185.17185.2 0.81 12-Jun K.LFNPLIR.L sp|Q9Y5B6|PAXB1_HUMAN 1 871.528 0.51 58943 17185 2 871.530039 436.7713 PAX3- and PAX7-binding protein 1 OS=Homo sapiens OX=9606 GN=PAXBP1 PE=1 SV=2 9.75 3397.6 - 536861 - - - 2.3705 - 1.165 0.157 - 95.9 1 2 0 0.0021 7 0 0 0 8.79E+06 1.72E+07 - - - 0.6839 0.996 230117_WJC_METTL3_WT_vs_EV_F07.17190.17190.2 0.0503 14-Jul R.LDNIFLTR.M "sp|Q9BQ52|RNZ2_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|V9GYS7|V9GYS7_HUMAN,tr|J3QLK4|J3QLK4_HUMAN,tr|V9GYU5|V9GYU5_HUMAN,tr|V9GZ72|V9GZ72_HUMAN,tr|J3QL08|J3QL08_HUMAN,tr|J3QRS2|J3QRS2_HUMAN" 8 990.5498 0.28 58946 17190 2 990.548489 496.2822 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 5.84 3398.2 - 3.56E+06 - - - -1.3548 - 1.524 0.259 - 137.2 1 2 0 -0.0013 8 0 0 0 4.29E+07 1.54E+08 - - - 2.2243 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.17191.17191.2 0.0251 16-Sep R.FAVGIVIGR.N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 930.5651 1.41 58947 17191 2 930.567709 466.2898 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3398.2 - 3.45E+06 - - - 2.8176 - 1.768 0.328 - 320.4 1 2 0 0.0026 9 0 0 0 9.55E+07 6.76E+07 - - - 3.1114 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17192.17192.2 0.296 16-Nov R.FAVGIVIGR[166.11].N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 940.5734 1.54 58948 17192 2 940.575451 471.294 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3398.3 - 3.14E+06 - - - 2.2263 - 1.941 0.369 - 461 1 2 0 0.0021 9 0 0 0 1.11E+08 7.19E+07 - - - 3.6845 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17201.17201.2 0.00126 18-Nov R.LLDYVPIGPR.F "sp|P46459|NSF_HUMAN,tr|K7EQD6|K7EQD6_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 4 1141.6495 1.49 58955 17201 2 1141.652705 571.832 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.84 3399.3 - 142122 - - - 2.7679 - 2.22 0.377 - 300.2 1 2 0 0.0032 10 0 0 0 4.57E+07 3.06E+07 - - - 4.0506 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17206.17206.2 0.0549 16-Sep K.AILVVFANK.Q "sp|P40616|ARL1_HUMAN,tr|B4DZG7|B4DZG7_HUMAN,tr|F8VYN9|F8VYN9_HUMAN" 3 973.5961 0.39 58958 17206 2 973.59798 487.8053 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 8.8 3399.9 - 2.52E+06 - - - 1.9793 - 1.921 0.284 - 292.6 1 2 0 0.0019 9 0 0 0 6.04E+07 1.53E+08 - - - 3.0267 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17208.17208.2 0.0563 14-Sep R.ITVLEALR.H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 913.5597 1.29 58960 17208 2 913.561184 457.7871 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3400 - 1.59E+06 - - - 1.6605 - 1.976 0.302 - 300.4 1 2 0 0.0015 8 0 0 0 1.02E+08 7.88E+07 - - - 3.3252 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17209.17209.2 0.00532 20-Dec K.ALADVATVLGR.A "sp|Q92542|NICA_HUMAN,tr|H0Y6T7|H0Y6T7_HUMAN" 2 1084.6241 4.23 58961 17209 2 1084.624227 543.3193 Nicastrin OS=Homo sapiens OX=9606 GN=NCSTN PE=1 SV=2 5.88 3400.1 - 418828 - - - 0.1558 - 2.141 0.271 - 349.4 1 2 0 0.0002 11 0 0 0 4.70E+06 1.11E+06 - - - 3.102 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.17213.17213.2 0.00451 14-Sep R.ITVLEALR[166.11].H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 923.5679 1.29 58963 17213 2 923.57169 462.7912 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3400.7 - 1.27E+06 - - - 4.0636 - 1.841 0.4 - 278.2 1 2 0 0.0038 8 0 0 0 1.02E+08 7.89E+07 - - - 3.8349 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.17217.17217.2 0.544 14-Aug R.IAYFTLPK.T sp|Q92900|RENT1_HUMAN 1 951.543 0.73 58967 17217 2 951.545486 476.7788 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.59 3400.9 - 1.50E+06 - - - 2.6609 - 1.565 0.289 - 179.7 1 2 0 0.0025 8 0 0 0 8.01E+07 1.10E+08 - - - 2.5256 0.974 230117_WJC_METTL3_WT_vs_EV_F07.17227.17227.2 0.00154 16-Aug F.VLVLYDEIK.K "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 3 1090.6274 0.13 58975 17227 2 1090.628979 546.321 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 4.37 3402.2 - 1.27E+06 - - - 1.4368 - 1.871 0.41 - 186.2 1 1 0 0.0016 9 0 0 0 1.16E+07 8.82E+07 - - - 3.8812 0.9928 230117_WJC_METTL3_WT_vs_EV_F07.17228.17228.2 2.67 14-Aug K.LILAGALR[166.11].L "sp|Q13614|MTMR2_HUMAN,tr|A0A6Q8PHS7|A0A6Q8PHS7_HUMAN,tr|C9JEX3|C9JEX3_HUMAN,tr|A0A6Q8PGS5|A0A6Q8PGS5_HUMAN,tr|A0A6Q8PHL9|A0A6Q8PHL9_HUMAN" 5 835.5519 1.44 58976 17228 2 835.552977 418.7832 Myotubularin-related protein 2 OS=Homo sapiens OX=9606 GN=MTMR2 PE=1 SV=4 9.75 3402.3 - 947323 - - - 1.2973 - 1.607 0.049 - 219.3 2 2 0 0.0011 8 0 0 0 5.68E+07 3.95E+07 - - - 0.6988 0.9827 230117_WJC_METTL3_WT_vs_EV_F07.17229.17229.2 0.215 16-Jul R.GLVGEIIK[136.11]R[166.11].F "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1001.6352 1.99 58977 17229 2 1001.636582 501.8249 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3402.3 - 6.13E+06 - - - 1.3448 - 1.325 0.033 - 143.7 1 2 0 0.0013 9 0 0 0 1.60E+08 8.03E+07 - - - 0.0985 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17230.17230.2 0.111 14-Sep K.LMNLWTER[166.11].F "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1071.5411 0.35 58978 17230 2 1071.542289 536.7778 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 3402.5 - 960927 - - - 1.1367 - 1.746 0.309 - 304.4 1 2 0 0.0012 8 0 0 0 3.30E+08 9.41E+08 - - - 3.0038 0.9922 230117_WJC_METTL3_WT_vs_EV_F07.17239.17239.2 0.0706 14-Aug R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 25.74 58986 17239 2 1000.557605 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3403.5 - 7.94E+06 - - - -1.727 - 1.361 0.249 - 168.6 1 2 0 -0.0017 8 0 0 0 1.62E+08 6.28E+06 - - - 1.8091 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.17240.17240.2 0.0737 14-Oct K.AGISFIIK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 847.5167 0.89 58987 17240 2 847.51824 424.7656 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.8 3403.6 - 2.87E+06 - - - 1.7699 - 1.584 0.153 - 241.6 1 2 0 0.0015 8 0 0 0 2.41E+09 2.69E+09 - - - 1.5578 0.9339 230117_WJC_METTL3_WT_vs_EV_F07.17245.17245.2 2.56 12-Jun K.EGIILFK.E sp|P05455|LA_HUMAN 1 818.4902 0.98 58992 17245 2 818.4929 410.2524 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 6.1 3404.1 - 654380 - - - 3.3098 - 1.199 0.014 - 116.8 1 2 0 0.0027 7 0 0 0 1.42E+08 1.44E+08 - - - -0.2814 0.9194 230117_WJC_METTL3_WT_vs_EV_F07.17252.17252.2 0.0669 16-Aug F.ADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 952.5957 14.05 58997 17252 2 952.597264 477.3051 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3405.1 - 2.84E+06 - - - 1.6229 - 1.41 0.307 - 171.7 1 1 0 0.0015 9 0 0 0 4.07E+07 2.89E+06 - - - 2.302 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17253.17253.2 2.97E-05 14-Oct K.LMNLWTER.F "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1061.5328 0.35 58998 17253 2 1061.534988 531.7737 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 3405.1 - 2.74E+06 - - - 2.0602 - 1.896 0.434 - 478.6 1 2 0 0.0022 8 0 0 0 3.30E+08 9.41E+08 - - - 4.1753 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17254.17254.2 0.000822 18-Nov R.LGGIGQFLAK[136.11].A sp|Q08211|DHX9_HUMAN 1 1010.6004 0.79 58999 17254 2 1010.602786 506.3075 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3405.2 - 3.47E+06 - - - 2.3451 - 2.329 0.236 - 306.6 1 2 0 0.0024 10 0 0 0 4.27E+08 5.39E+08 - - - 3.1432 0.9753 230117_WJC_METTL3_WT_vs_EV_F07.17255.17255.2 1.74 14-Jul R.EILETLIK.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 957.5746 1.62 59000 17255 2 957.5775 479.7946 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3405.2 - 2.91E+06 - - - 2.9773 - 1.461 0.009 - 153.3 1 2 0 0.0029 8 0 0 0 2.20E+08 1.36E+08 - - - 0.25 0.9934 230117_WJC_METTL3_WT_vs_EV_F07.17259.17259.2 0.2 12-Jun K.GLLDDLR[166.11].N sp|Q07065|CKAP4_HUMAN 1 810.4475 1.4 59004 17259 2 810.449707 406.231 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.21 3405.7 - 215177 - - - 2.738 - 1.194 0.203 - 106.7 1 2 0 0.0022 7 0 0 0 4.14E+07 2.97E+07 - - - 1.1015 0.8615 230117_WJC_METTL3_WT_vs_EV_F07.17262.17262.2 9.44 14-May K.FIIPNVVK.Y "sp|P00338|LDHA_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 3 928.5746 0.92 59005 17262 2 928.57647 465.2946 L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2 8.75 3406.1 - 2.06E+06 - - - 2.0257 - 0.789 0.063 - 62.7 1 2 0 0.0019 8 0 0 0 6.47E+07 7.02E+07 - - - -1.209 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17263.17263.2 0.00401 16-Aug K.SSLNPILFR[166.11].G "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1055.6003 1.3 59006 17263 2 1055.602407 528.8074 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 9.47 3406.1 - 2.23E+06 - - - 1.996 - 1.724 0.32 - 171.8 1 2 0 0.0021 9 0 0 0 1.73E+08 1.33E+08 - - - 2.9796 0.996 230117_WJC_METTL3_WT_vs_EV_F07.17265.17265.2 0.058 14-Jul K.AVPSWFVR[166.11].V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 970.5264 2.26 59008 17265 2 970.528494 486.2705 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3406.2 - 2.58E+06 - - - 2.1504 - 1.388 0.168 - 191.5 1 2 0 0.0021 8 0 0 0 1.73E+08 7.67E+07 - - - 1.27 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.17267.17267.2 0.37 16-Aug R.VLIFSQMTR[166.11].V "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 1103.6037 1 59010 17267 2 1103.605798 552.8091 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 9.72 3406.4 - 1.47E+06 - - - 1.9273 - 1.487 0.237 - 142 1 2 0 0.0021 9 0 0 0 2.17E+07 2.16E+07 - - - 1.9387 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17269.17269.2 0.000788 18-Nov K.VALDLDPYVK.K sp|O95295|SNAPN_HUMAN 1 1131.6176 2.52 59012 17269 2 1131.619341 566.8161 SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN PE=1 SV=1 4.21 3406.5 - 782756 - - - 1.5597 - 2.201 0.418 - 372.2 1 2 0 0.0018 10 0 0 0 3.30E+07 1.31E+07 - - - 4.3299 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.17270.17270.2 0.0916 12-Jun K.ISFELMR.E "sp|Q9UNE7|CHIP_HUMAN,tr|H3BUD0|H3BUD0_HUMAN,tr|H3BTA3|H3BTA3_HUMAN" 3 894.4633 6.04 59013 17270 2 894.464733 448.2389 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 6 3406.6 - 780627 - - - 1.5752 - 1.343 0.26 - 88 1 2 0 0.0014 7 0 0 0 2.73E+07 4.52E+06 - - - 1.8953 0.9742 230117_WJC_METTL3_WT_vs_EV_F07.17271.17271.2 2.51 16-Aug K.ATEMLIFGK.K "sp|O75521|ECI2_HUMAN,tr|A0A0C4DGA2|A0A0C4DGA2_HUMAN" 2 1008.5314 0.09 59014 17271 2 1008.532289 505.273 Enoyl-CoA delta isomerase 2 OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4 6.05 3406.7 - 248877 - - - 0.8775 - 0.966 0.125 - 73.6 1 2 0 0.0009 9 0 0 0 1.06E+07 1.18E+08 - - - -0.1361 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.17274.17274.2 3.28 14-Aug R.EILETLIK[136.11].G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 965.5888 1.62 59016 17274 2 965.590652 483.8017 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3407.1 - 6.32E+06 - - - 1.8673 - 1.667 0.125 - 223.2 1 2 0 0.0018 8 0 0 0 2.20E+08 1.36E+08 - - - 1.5049 0.8559 230117_WJC_METTL3_WT_vs_EV_F07.17275.17275.2 0.336 20-Jul R.LYPVLQQSLVR.A sp|Q5RKV6|EXOS6_HUMAN 1 1314.766 0.89 59017 17275 2 1314.774875 658.3903 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.75 3407.2 - 502045 - - - 6.7715 - 1.198 0.158 - 124.1 1 2 0 0.0089 11 0 0 0 1.20E+07 1.35E+07 - - - 0.6939 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17276.17276.2 0.000506 13/18 R.LGGIGQFLAK.A sp|Q08211|DHX9_HUMAN 1 1002.5862 0.81 59018 17276 2 1002.587805 502.3004 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3407.2 - 6.81E+06 - - - 1.5849 - 2.332 0.285 - 381.2 1 2 0 0.0016 10 0 0 0 4.25E+08 5.23E+08 - - - 3.509 0.9674 230117_WJC_METTL3_WT_vs_EV_F07.17277.17277.2 0.375 14-Sep R.IASFLQLK.N "sp|P42694|HELZ_HUMAN,tr|J3KT20|J3KT20_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 4 918.5539 0.58 59019 17277 2 918.56045 460.2842 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.75 3407.4 - 1.25E+06 - - - 7.1809 - 1.681 0.22 - 129.4 1 2 0 0.0066 8 0 0 0 4.45E+07 7.62E+07 - - - 2.2303 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17279.17279.2 0.000174 16-Nov K.LNNLVLFDK[136.11].A sp|P62851|RS25_HUMAN 1 1082.6215 1.01 59021 17279 2 1082.621088 542.318 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3407.6 - 506446 - - - -0.423 - 2.51 0.362 - 370.6 1 2 0 -0.0005 9 0 0 0 8.26E+08 8.16E+08 - - - 4.377 0.9725 230117_WJC_METTL3_WT_vs_EV_F07.17280.17280.2 1.78 12-Jul K.GLLDDLR.N sp|Q07065|CKAP4_HUMAN 1 800.4392 1.36 59022 17280 2 800.440667 401.2269 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.21 3407.8 - 451960 - - - 1.8103 - 1.162 0.042 - 177.4 1 2 0 0.0014 7 0 0 0 3.99E+07 2.93E+07 - - - -0.1735 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.17281.17281.2 0.0378 22-Sep -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 1.24 59023 17281 2 1306.77075 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3407.9 - 401379 - - - 1.8902 - 1.496 0.302 - 143.3 1 2 0 0.0025 12 0 0 0 1.39E+07 1.11E+07 - - - 2.3306 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17285.17285.2 0.00386 18-Aug R.VLISTDVWAR[166.11].G "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1168.648 0.95 59026 17285 2 1168.648414 585.3313 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.81 3408.4 - 2.50E+06 - - - 0.3731 - 1.796 0.481 - 181.5 1 2 0 0.0004 10 0 0 0 1.30E+08 1.36E+08 - - - 4.228 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17287.17287.2 0.00817 14-Jun K.AVPSWFVR.V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 960.5181 2.26 59027 17287 2 960.519207 481.2663 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3408.6 - 7.02E+06 - - - 1.114 - 1.39 0.437 - 146.2 1 2 0 0.0011 8 0 0 0 1.74E+08 7.67E+07 - - - 3.2615 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17288.17288.2 0.000615 16-Aug R.AGFVPVYLR[166.11].Q "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1030.5839 0.76 59028 17288 2 1030.585119 516.2992 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 8.79 3408.6 - 2.93E+06 - - - 1.1615 - 1.561 0.424 - 203.5 1 2 0 0.0012 9 0 0 0 7.15E+07 9.37E+07 - - - 3.4606 0.9965 230117_WJC_METTL3_WT_vs_EV_F07.17302.17302.2 0.18 14-Jun R.VIPLPQWK.A sp|Q96ES7|SGF29_HUMAN 1 979.5855 1.76 59036 17302 2 979.586718 490.8 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 8.72 3410.2 - 804309 - - - 1.2556 - 1.196 0.225 - 125.7 1 2 0 0.0012 8 0 0 0 3.05E+07 1.73E+07 - - - 1.2423 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17321.17321.2 0.00185 16-Dec K.LNNLVLFDK.A sp|P62851|RS25_HUMAN 1 1074.6073 1.01 59049 17321 2 1074.608287 538.3109 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3412.6 - 3.55E+07 - - - 0.8757 - 2.525 0.369 - 553.2 1 2 0 0.0009 9 0 0 0 8.27E+08 8.17E+08 - - - 4.4458 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17323.17323.2 0.000282 14-Sep K.MVGFIIGR.G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 891.5 1.41 59050 17323 2 891.500387 446.7573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3412.8 - 1.51E+06 - - - 0.3847 - 1.57 0.441 - 306.8 1 2 0 0.0003 8 0 0 0 3.87E+08 2.74E+08 - - - 3.6585 0.9959 230117_WJC_METTL3_WT_vs_EV_F07.17324.17324.2 0.041 16-Sep R.FGIWTGEYK[136.11].C sp|Q9NUD5|ZCHC3_HUMAN 1 1107.548 1.74 59051 17324 2 1107.551805 554.7813 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 6 3412.9 - 528947 - - - 3.394 - 1.496 0.221 - 158.2 1 2 0 0.0038 9 0 0 0 1.98E+07 1.14E+07 - - - 1.8374 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17330.17330.2 0.0086 14-Aug K.LFDFVNAK.K "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 952.5018 0.35 59055 17330 2 952.503084 477.2582 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 5.84 3413.7 - 1.43E+06 - - - 1.3291 - 1.503 0.397 - 138.4 1 2 0 0.0013 8 0 0 0 5.30E+07 1.50E+08 - - - 3.2017 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.17331.17331.2 0.00291 14-Aug R.TFLVPEIK.S sp|Q9P1Y5|CAMP3_HUMAN 1 945.5535 0.86 59056 17331 2 945.554506 473.784 Calmodulin-regulated spectrin-associated protein 3 OS=Homo sapiens OX=9606 GN=CAMSAP3 PE=1 SV=2 5.66 3413.9 - 584426 - - - 1.0438 - 1.482 0.255 - 215.1 1 2 0 0.001 8 0 0 0 1.27E+07 1.48E+07 - - - 2.1106 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.17333.17333.2 0.00216 14-Jul K.LFIGMISK.K "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 907.5201 1.24 59058 17333 2 907.521523 454.7673 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.75 3414.1 - 396296 - - - 1.5559 - 1.448 0.338 - 113.4 1 2 0 0.0014 8 0 0 0 7.34E+06 5.92E+06 - - - 2.6535 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.17343.17343.2 0.000315 22-Sep R.IVPGQFLAVDPK.G sp|Q15393|SF3B3_HUMAN 1 1282.7285 1.23 59066 17343 2 1282.734556 642.3715 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3415.3 - 206221 - - - 4.7025 - 1.836 0.379 - 190.2 1 2 0 0.006 12 0 0 0 2.07E+07 1.69E+07 - - - 3.4371 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17344.17344.2 1.59E-05 22-Aug R.IVPGQFLAVDPK[136.11].G sp|Q15393|SF3B3_HUMAN 1 1290.7427 1.23 59067 17344 2 1290.744773 646.3786 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3415.4 - 166090 - - - 1.5875 - 2.115 0.445 - 150.7 1 2 0 0.0021 12 0 0 0 2.07E+07 1.69E+07 - - - 4.298 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17347.17347.2 0.000356 22-Sep R.ILYIVASDPYSR.L "sp|Q9ULT8|HECD1_HUMAN,tr|H0YJD4|H0YJD4_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN,tr|H0YJP0|H0YJP0_HUMAN" 4 1395.7398 5.77 59070 17347 2 1395.74202 698.8772 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 5.83 3415.8 - 135720 - - - 1.5784 - 1.955 0.48 - 273.3 1 2 0 0.0022 12 0 0 0 3.26E+06 5.64E+05 - - - 4.3495 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17351.17351.2 0.0141 18-Oct R.LASMATLLAR.A sp|Q96P11|NSUN5_HUMAN 1 1045.5954 1.3 59073 17351 2 1045.597623 523.805 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 9.75 3416.4 - 1.63E+06 - - - 2.1251 - 2.119 0.371 - 269.6 1 2 0 0.0022 10 0 0 0 1.74E+08 1.34E+08 - - - 3.8766 0.926 230117_WJC_METTL3_WT_vs_EV_F07.17356.17356.2 0.00303 22-Jul R.VINEPTAAALAY.G "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1231.6449 - 59077 17356 2 1231.647084 616.8297 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4 3416.9 - 737154 - - - 1.8114 - 1.699 0.271 - 106.4 1 1 0 0.0022 12 0 0 0 - - - - - 2.4365 0.9943 230117_WJC_METTL3_WT_vs_EV_F07.17357.17357.2 0.00128 20-Sep R.LYPVLQQSLVR[166.11].A sp|Q5RKV6|EXOS6_HUMAN 1 1324.7742 -1 59078 17357 2 1324.781005 663.3944 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.75 3417.1 - 591220 - - - 5.105 - 1.552 0.332 - 164.6 1 2 0 0.0068 11 0 0 0 0.00E+00 0.00E+00 - - - 2.6801 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.17363.17363.2 0.954 14-Aug K.GWGLLGPR[166.11].N "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 864.4845 0.8 59083 17363 2 864.486484 433.2495 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 9.75 3417.8 - 928655 - - - 2.2464 - 1.73 0.221 - 261.8 1 2 0 0.0019 8 0 0 0 2.63E+07 3.29E+07 - - - 2.3258 0.999 230117_WJC_METTL3_WT_vs_EV_F07.17364.17364.2 0.0226 18-Aug R.LINLVGESLR.L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1112.6554 4.65 59084 17364 2 1112.656695 557.335 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6 3417.9 - 231532 - - - 1.2007 - 1.624 0.271 - 141.4 1 2 0 0.0013 10 0 0 0 1.16E+08 2.50E+07 - - - 2.3957 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.17365.17365.2 0.0719 12-Jul R.GFLYFNR[166.11].Q sp|Q10570|CPSF1_HUMAN 1 925.4686 1.52 59085 17365 2 925.469608 463.7416 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3418 - 779749 - - - 1.1356 - 1.572 0.242 - 201.9 1 2 0 0.0011 7 0 0 0 1.08E+07 7.10E+06 - - - 2.2614 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.17366.17366.2 0.0567 14-Aug R.GIVTFQFR[166.11].G sp|P26572|MGAT1_HUMAN 1 976.537 0.67 59086 17366 2 976.538927 489.2758 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 9.75 3418.1 - 588379 - - - 2.003 - 1.705 0.184 - 276.6 1 2 0 0.002 8 0 0 0 6.31E+06 9.39E+06 - - - 2.0086 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17374.17374.2 0.00168 24-Oct K.LLLGAGAVAYGVR.E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1258.7398 1.38 59092 17374 2 1258.741963 630.3772 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3419 - 532768 - - - 1.7525 - 2.131 0.424 - 276 1 2 0 0.0022 13 0 0 0 8.55E+07 6.19E+07 - - - 4.1138 1 230117_WJC_METTL3_WT_vs_EV_F07.17375.17375.2 0.000143 14/24 K.LLLGAGAVAYGVR[166.11].E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1268.748 1.38 59093 17375 2 1268.750675 635.3813 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3419.1 - 381590 - - - 2.0871 - 2.532 0.487 - 669.5 1 2 0 0.0026 13 0 0 0 8.55E+07 6.21E+07 - - - 5.0215 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17376.17376.2 0.0441 20-Aug K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.45 59094 17376 2 1245.770109 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3419.3 - 288164 - - - 1.3494 - 1.641 0.325 - 143.2 1 2 0 0.0017 11 0 0 0 1.96E+07 1.36E+07 - - - 2.7808 1 230117_WJC_METTL3_WT_vs_EV_F07.17381.17381.2 7.42E-06 14-Oct K.MVGFIIGR[166.11].G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 901.5083 1.42 59098 17381 2 901.509831 451.7614 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3419.9 - 2.84E+07 - - - 1.6827 - 1.909 0.54 - 376.1 1 2 0 0.0015 8 0 0 0 3.90E+08 2.74E+08 - - - 4.979 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17383.17383.2 0.106 14-Oct R.IVEVLLMK.D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 943.5776 1 59099 17383 2 943.580212 472.7961 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3420.1 - 2.02E+06 - - - 2.7417 - 2.109 0.353 - 274.5 1 2 0 0.0026 8 0 0 0 1.82E+08 1.82E+08 - - - 3.898 0.9531 230117_WJC_METTL3_WT_vs_EV_F07.17386.17386.2 0.0125 16-Nov D.IPIILVGNK.S "sp|P55040|GEM_HUMAN,sp|Q8IXI2|MIRO1_HUMAN,tr|H7BXZ6|H7BXZ6_HUMAN" 3 965.6274 1.95 59102 17386 2 965.630266 483.821 GTP-binding protein GEM OS=Homo sapiens OX=9606 GN=GEM PE=1 SV=1 8.75 3420.4 - 746106 - - - 3.0167 - 2.208 0.346 - 351 1 1 0 0.0029 9 0 0 0 5.63E+06 2.88E+06 - - - 3.8872 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17387.17387.2 0.006 16-Aug R.TFTNVYWMK[136.11].V sp|Q9HBH1|DEFM_HUMAN 1 1196.578 1 59103 17387 2 1196.580111 599.2963 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 8.26 3420.6 - 433713 - - - 1.7926 - 1.475 0.438 - 181.1 1 2 0 0.0021 9 0 0 0 5.97E+06 5.97E+06 - - - 3.3998 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.17397.17397.2 0.0275 14-Nov R.IVEVLLMK[136.11].D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 951.5918 1 59112 17397 2 951.595379 476.8032 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3421.9 - 1.00E+07 - - - 3.7348 - 2.31 0.23 - 363.3 1 2 0 0.0036 8 0 0 0 1.82E+08 1.82E+08 - - - 3.2638 1 230117_WJC_METTL3_WT_vs_EV_F07.17398.17398.2 0.00311 18-Nov K.VVDLLAPYAK.G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1087.6277 1.61 59113 17398 2 1087.633246 544.8211 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3422 - 2.52E+06 - - - 5.056 - 2.337 0.444 - 408.9 1 2 0 0.0055 10 0 0 0 3.88E+08 2.41E+08 - - - 4.6881 0.9693 230117_WJC_METTL3_WT_vs_EV_F07.17400.17400.2 2.36 16-Jul R.IELLIDAAR[166.11].Q sp|Q8IU81|I2BP1_HUMAN 1 1022.6 1.34 59115 17400 2 1022.603661 512.3073 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.37 3422.2 - 2.01E+06 - - - 3.6133 - 1.69 0.026 - 105.4 7 2 0 0.0037 9 0 0 0 1.36E+07 1.01E+07 - - - 0.3724 0.8994 230117_WJC_METTL3_WT_vs_EV_F07.17405.17405.2 0.0133 16-Sep D.IPIILVGNK[136.11].S "sp|P55040|GEM_HUMAN,sp|Q8IXI2|MIRO1_HUMAN,tr|H7BXZ6|H7BXZ6_HUMAN" 3 973.6416 1.95 59120 17405 2 973.645034 487.8281 GTP-binding protein GEM OS=Homo sapiens OX=9606 GN=GEM PE=1 SV=1 8.75 3422.8 - 634945 - - - 3.5752 - 1.765 0.332 - 177 1 1 0 0.0035 9 0 0 0 5.63E+06 2.88E+06 - - - 3.1357 0.9917 230117_WJC_METTL3_WT_vs_EV_F07.17408.17408.2 0.0561 12-Jul R.WLLDNVR[166.11].K "sp|Q14409|GLPK3_HUMAN,sp|P32189|GLPK_HUMAN,tr|H7C2A0|H7C2A0_HUMAN" 3 924.5057 1.77 59123 17408 2 924.509557 463.2601 Glycerol kinase 3 OS=Homo sapiens OX=9606 GN=GK3P PE=2 SV=2 5.84 3423.2 - 459240 - - - 4.2033 - 1.427 0.207 - 121 1 2 0 0.0039 7 0 0 0 1.46E+07 8.27E+06 - - - 1.6953 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17409.17409.2 0.000233 16-Aug R.TFTNVYWMK.V sp|Q9HBH1|DEFM_HUMAN 1 1188.5638 0.98 59124 17409 2 1188.566773 595.2892 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 8.26 3423.3 - 371228 - - - 2.5299 - 1.756 0.425 - 176.6 1 2 0 0.003 9 0 0 0 5.78E+06 5.91E+06 - - - 3.808 1 230117_WJC_METTL3_WT_vs_EV_F07.17416.17416.2 0.00565 18-Nov K.VVDLLAPYAK[136.11].G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1095.6419 1.61 59129 17416 2 1095.644335 548.8282 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3424.1 - 4.68E+06 - - - 2.1795 - 2.14 0.473 - 446.8 1 2 0 0.0024 10 0 0 0 3.91E+08 2.42E+08 - - - 4.6575 0.9917 230117_WJC_METTL3_WT_vs_EV_F07.17418.17418.2 0.0621 12-Jun R.DFYFSVK.L sp|Q9NY12|GAR1_HUMAN 1 904.4331 0.63 59131 17418 2 904.436641 453.2238 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3424.2 - 2.60E+06 - - - 3.9483 - 0.998 0.339 - 152.5 1 2 0 0.0036 7 0 0 0 5.80E+07 9.25E+07 - - - 1.5374 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.17419.17419.2 0.157 14-Aug R.LLNIWQER.S sp|Q9NQG5|RPR1B_HUMAN 1 1070.5873 2.8 59132 17419 2 1070.590031 536.3009 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 6 3424.3 - 1.87E+06 - - - 2.5706 - 1.864 0.124 - 220.3 1 2 0 0.0028 8 0 0 0 5.38E+07 1.92E+07 - - - 1.8341 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17420.17420.2 1.21E-06 18-Oct K.VVDDEIYYFR.K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1317.6241 2.07 59133 17420 2 1317.625083 659.8193 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3424.4 - 925538 - - - 0.7324 - 2.152 0.401 - 368.6 1 2 0 0.001 10 0 0 0 1.91E+07 9.26E+06 - - - 4.1417 0.9605 230117_WJC_METTL3_WT_vs_EV_F07.17424.17424.2 4.09 16-Jun R.MLPPPPMWR.R "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 5 1123.5671 0.79 59137 17424 2 1123.571577 562.7908 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 9.5 3424.8 - 302691 - - - 4.0042 - 1.207 0.107 - 113.6 1 2 0 0.0045 9 0 0 0 2.78E+07 3.51E+07 - - - 0.3742 0.999 230117_WJC_METTL3_WT_vs_EV_F07.17427.17427.2 0.0122 22-Dec K.VLAGVLDSVDVR[166.11].L "sp|Q8NCH0|CHSTE_HUMAN,tr|H0YN65|H0YN65_HUMAN" 2 1251.7062 2.66 59140 17427 2 1251.706027 626.8604 Carbohydrate sulfotransferase 14 OS=Homo sapiens OX=9606 GN=CHST14 PE=1 SV=2 4.21 3425.2 - 160761 - - - -0.1558 - 2.115 0.268 - 600.5 1 2 0 -0.0002 12 0 0 0 1.08E+07 4.08E+06 - - - 2.9913 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17431.17431.2 0.0156 16-Aug R.AFLGQVLVR.R "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1001.6022 0.2 59142 17431 2 1001.602761 501.8084 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 9.79 3425.8 - 3.16E+06 - - - 0.5591 - 1.613 0.441 - 177.2 1 2 0 0.0006 9 0 0 0 6.14E+07 3.05E+08 - - - 3.6812 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17432.17432.2 0.0149 14-Aug R.LLNIWQER[166.11].S sp|Q9NQG5|RPR1B_HUMAN 1 1080.5955 3.33 59143 17432 2 1080.597361 541.3051 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 6 3425.9 - 1.19E+06 - - - 1.6769 - 1.948 0.251 - 238.3 1 2 0 0.0018 8 0 0 0 5.27E+07 1.58E+07 - - - 2.9054 0.9966 230117_WJC_METTL3_WT_vs_EV_F07.17438.17438.2 0.346 12-Jun R.VLFSLVK.R "sp|Q14999|CUL7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 2 804.5109 1.02 59149 17438 2 804.512482 403.2627 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 8.72 3426.6 - 410555 - - - 1.9341 - 1.348 0.184 - 130.3 1 2 0 0.0016 7 0 0 0 4.84E+06 4.74E+06 - - - 1.3457 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17448.17448.2 9.70E-05 18-Dec K.VVDDEIYYFR[166.11].K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1327.6324 2.07 59157 17448 2 1327.636437 664.8235 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3427.9 - 769097 - - - 3.0498 - 1.945 0.473 - 552.4 1 2 0 0.004 10 0 0 0 1.91E+07 9.26E+06 - - - 4.3903 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17452.17452.2 8.89E-07 13/22 R.YVVGVLEAAGVR[166.11].Y sp|Q9H9S5|FKRP_HUMAN 1 1241.7007 0.38 59161 17452 2 1241.702295 621.8576 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 6 3428.2 - 1.01E+06 - - - 1.2507 - 2.362 0.356 - 528.9 1 2 0 0.0016 12 0 0 0 4.91E+06 1.29E+07 - - - 3.9314 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.17455.17455.2 0.000649 18-Sep K.WVGVILDEAK.G "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1128.6179 2.54 59164 17455 2 1128.62326 565.3162 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3428.6 - 498648 - - - 4.7403 - 1.966 0.378 - 181.6 1 2 0 0.0053 10 0 0 0 1.47E+08 5.80E+07 - - - 3.7182 0.9917 230117_WJC_METTL3_WT_vs_EV_F07.17456.17456.2 0.254 14-Jun K.AITAATLK.F sp|P11277|SPTB1_HUMAN 1 787.4804 0.64 59165 17456 2 787.481565 394.7475 "Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB PE=1 SV=5" 8.8 3428.8 - 488462 - - - 1.5378 - 1.199 0.138 - 114.5 1 2 0 0.0012 8 0 0 0 4.78E+06 7.50E+06 - - - 0.6072 0.9459 230117_WJC_METTL3_WT_vs_EV_F07.17465.17465.2 0.0591 14-Jul V.VGDIAQVK[136.11].Y "sp|Q01814|AT2B2_HUMAN,sp|P20020|AT2B1_HUMAN,sp|Q16720|AT2B3_HUMAN,sp|P23634|AT2B4_HUMAN,tr|A0A804HKZ0|A0A804HKZ0_HUMAN,tr|A0A2U3TZI3|A0A2U3TZI3_HUMAN,tr|A0A2U3U055|A0A2U3U055_HUMAN" 7 836.4847 1.92 59172 17465 2 836.484986 419.2496 Plasma membrane calcium-transporting ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2B2 PE=1 SV=2 5.81 3429.9 - 1.35E+06 - - - 0.3204 - 1.482 0.381 - 123.2 1 1 0 0.0003 8 0 0 0 1.65E+07 8.62E+06 - - - 3.0414 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.17466.17466.2 0.0725 12-Aug K.TYDLLFK.L sp|P61026|RAB10_HUMAN 1 898.48 0.46 59173 17466 2 898.481103 450.2473 Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1 5.5 3430 - 890278 - - - 1.2054 - 1.392 0.26 - 227.7 1 2 0 0.0011 7 0 0 0 1.84E+07 4.00E+07 - - - 2.009 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17469.17469.2 0.0374 20-Jun K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 0.95 59176 17469 2 1235.761713 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3430.4 - 448929 - - - 1.2583 - 1.607 0.338 - 100.1 1 2 0 0.0016 11 0 0 0 7.01E+06 7.38E+06 - - - 2.8203 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17475.17475.2 0.0597 14-Aug R.AYILNLVK[136.11].Q sp|P50991|TCPD_HUMAN 1 940.5837 8.21 59180 17475 2 940.584663 471.2991 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.63 3431.2 - 7.79E+06 - - - 1.0196 - 1.548 0.328 - 232.1 1 2 0 0.001 8 0 0 0 1.33E+09 1.63E+08 - - - 2.7812 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17477.17477.2 0.000549 16-Oct R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 0.96 59182 17477 2 997.606433 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3431.3 - 2.33E+06 - - - 1.269 - 2.075 0.45 - 266.9 1 2 0 0.0013 9 0 0 0 3.23E+09 3.36E+09 - - - 4.4761 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17478.17478.2 0.024 16-Aug R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.96 59183 17478 2 989.593403 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3431.4 - 1.35E+06 - - - 2.4616 - 1.984 0.337 - 167.7 1 2 0 0.0024 9 0 0 0 3.25E+09 3.39E+09 - - - 3.5114 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.17489.17489.2 0.00824 14-Jul K.FYFEELGK[136.11].Y sp|Q10471|GALT2_HUMAN 1 1039.5106 0.91 59192 17489 2 1039.512204 520.7626 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3432.6 - 559035 - - - 1.545 - 1.207 0.302 - 103.3 1 2 0 0.0016 8 0 0 0 4.07E+07 4.50E+07 - - - 1.8385 1 230117_WJC_METTL3_WT_vs_EV_F07.17492.17492.2 0.000288 28-Dec R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 6.99 59195 17492 2 1484.91139 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3432.9 - 313452 - - - 2.3604 - 2.198 0.492 - 375.1 1 2 0 0.0035 15 0 0 0 6.20E+07 8.86E+06 - - - 4.61 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.17497.17497.2 0.461 12-Aug K.TYDLLFK[136.11].L sp|P61026|RAB10_HUMAN 1 906.4942 0.84 59198 17497 2 906.494264 454.2544 Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1 5.5 3433.6 - 2.16E+06 - - - 0.0485 - 1.449 0.27 - 178.2 1 2 0 0 7 0 0 0 1.72E+07 2.05E+07 - - - 2.2103 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17498.17498.2 0.0058 18-Dec K.WVGVILDEAK[136.11].G "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1136.6321 2.53 59199 17498 2 1136.633908 569.3233 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3433.7 - 1.48E+06 - - - 1.5819 - 2.264 0.384 - 449.9 1 2 0 0.0018 10 0 0 0 1.46E+08 5.79E+07 - - - 4.1575 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17500.17500.2 0.00374 18-Oct R.LLFNDVQTLK.D "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1189.6707 1.06 59201 17500 2 1189.674014 595.8426 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.84 3434 - 780586 - - - 2.8075 - 2.056 0.368 - 269.3 1 2 0 0.0033 10 0 0 0 2.22E+07 2.10E+07 - - - 3.7699 0.998 230117_WJC_METTL3_WT_vs_EV_F07.17502.17502.2 0.126 18-Sep R.FSNLLGTVYR[166.11].R "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN,tr|C9J544|C9J544_HUMAN" 3 1178.6323 0.97 59203 17502 2 1178.634198 590.3234 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 8.75 3434.2 - 460080 - - - 1.5866 - 1.727 0.157 - 251.4 1 2 0 0.0019 10 0 0 0 1.00E+07 1.03E+07 - - - 1.7251 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17509.17509.2 0.00878 18-Sep R.VVLPIEAPIR[166.11].M sp|P00403|COX2_HUMAN 1 1115.6942 1.69 59208 17509 2 1115.695967 558.8544 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 5.97 3435 - 382462 - - - 1.5838 - 1.943 0.437 - 351.6 1 2 0 0.0018 10 0 0 0 5.53E+08 3.27E+08 - - - 4.1222 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.17510.17510.2 0.000969 18-Aug R.VVLPIEAPIR.M sp|P00403|COX2_HUMAN 1 1105.6859 1.69 59209 17510 2 1105.688769 553.8502 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 5.97 3435.1 - 372750 - - - 2.5676 - 1.59 0.358 - 247.2 1 2 0 0.0028 10 0 0 0 5.53E+08 3.27E+08 - - - 2.9787 0.9753 230117_WJC_METTL3_WT_vs_EV_F07.17512.17512.2 0.868 14-May R.VDFTFYPR[166.11].R "sp|Q9H857|NT5D2_HUMAN,tr|H7C519|H7C519_HUMAN" 2 1053.5159 1.11 59211 17512 2 1053.519165 527.7652 5'-nucleotidase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=NT5DC2 PE=1 SV=1 5.81 3435.3 - 202546 - - - 3.0972 - 1.107 0.129 - 44 1 2 0 0.0033 8 0 0 0 6.30E+06 5.70E+06 - - - 0.2994 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17515.17515.2 0.0934 14-Oct K.IDLTLLNR.L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 956.5655 1.27 59213 17515 2 956.565576 479.29 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.84 3435.7 - 1.83E+07 - - - 0.0993 - 2.159 0.303 - 352.4 1 2 0 0.0001 8 0 0 0 9.53E+07 7.49E+07 - - - 3.6001 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17517.17517.2 0.00514 16-Sep R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 567.97 59214 17517 2 1006.570817 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3435.9 - 2.56E+06 - - - 0.913 - 1.836 0.507 - 197.4 1 2 0 0.0009 9 0 0 0 4.95E+08 8.71E+05 - - - 4.5432 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17518.17518.2 0.0717 16-Aug K.VVLPC[160.03]NLLR[166.11].M "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1092.6353 8.87 59215 17518 2 1092.637036 547.3249 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 8.22 3436 - 578557 - - - 1.5833 - 1.432 0.375 - 265 1 2 0 0.0017 9 0 0 0 4.32E+08 4.87E+07 - - - 2.849 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.17519.17519.2 0.13 14-Aug K.FYFEELGK.Y sp|Q10471|GALT2_HUMAN 1 1031.4964 0.76 59216 17519 2 1031.49738 516.7555 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3436 - 1.26E+06 - - - 0.952 - 1.567 0.285 - 227.4 1 2 0 0.001 8 0 0 0 3.37E+07 4.45E+07 - - - 2.5004 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17521.17521.2 0.00132 18-Aug R.LLFNDVQTLK[136.11].D "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1197.6849 1.06 59218 17521 2 1197.687718 599.8497 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.84 3436.2 - 651546 - - - 2.3746 - 1.886 0.349 - 149.8 1 2 0 0.0028 10 0 0 0 2.22E+07 2.10E+07 - - - 3.3888 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17522.17522.2 8.93E-05 20-Oct R.FLPEFAGTQLK.L sp|Q9UBZ4|APEX2_HUMAN 1 1249.6707 1.41 59219 17522 2 1249.672289 625.8426 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 6 3436.3 - 625835 - - - 1.2923 - 1.727 0.342 - 365.8 1 2 0 0.0016 11 0 0 0 6.07E+07 4.31E+07 - - - 3.0446 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17523.17523.2 0.753 18-Sep K.IYVISLAEPR.L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1159.6601 1.63 59220 17523 2 1159.663126 580.8373 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3436.4 - 555420 - - - 2.6008 - 2.019 0.36 - 396.5 1 2 0 0.003 10 0 0 0 1.38E+08 8.48E+07 - - - 3.6602 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.17529.17529.2 0.0828 14-Jul R.AYILNLVK.Q sp|P50991|TCPD_HUMAN 1 932.5695 7.62 59225 17529 2 932.570307 467.292 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.63 3437.1 - 3.54E+07 - - - 0.8611 - 1.354 0.269 - 162.1 1 2 0 0.0008 8 0 0 0 1.16E+09 1.52E+08 - - - 1.9416 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17531.17531.2 0.0737 14-Sep K.IDLTLLNR[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 966.5738 1.27 59226 17531 2 966.57508 484.2942 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.84 3437.3 - 6.57E+06 - - - 1.375 - 2.192 0.322 - 239.3 1 2 0 0.0013 8 0 0 0 9.53E+07 7.49E+07 - - - 3.7858 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.17536.17536.2 0.00241 20-Aug R.FLPEFAGTQLK[136.11].L sp|Q9UBZ4|APEX2_HUMAN 1 1257.6849 1.41 59231 17536 2 1257.683142 629.8497 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 6 3437.9 - 1.21E+06 - - - -1.3771 - 1.574 0.341 - 219.3 1 2 0 -0.0017 11 0 0 0 6.07E+07 4.31E+07 - - - 2.7862 1 230117_WJC_METTL3_WT_vs_EV_F07.17538.17538.2 0.000485 13/22 R.LNVGGTYFLTTR[166.11].Q "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1350.7171 0.39 59233 17538 2 1350.719886 676.3658 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3438.1 - 1.15E+06 - - - 2.0471 - 2.109 0.487 - 527.8 1 2 0 0.0028 12 0 0 0 4.14E+06 1.07E+07 - - - 4.6005 0.9426 230117_WJC_METTL3_WT_vs_EV_F07.17540.17540.2 4.43 18-Jun R.TILMC[160.03]GPLIK[136.11].E "sp|Q8IZL8|PELP1_HUMAN,tr|E7EV54|E7EV54_HUMAN,tr|C9JFV4|C9JFV4_HUMAN" 3 1152.649 0.32 59235 17540 2 1152.652016 577.3318 "Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2" 7.89 3438.4 - 180895 - - - 2.5966 - 0.957 0.085 - 50.7 1 2 0 0.003 10 0 0 0 6.80E+05 2.13E+06 - - - -0.4548 0.999 230117_WJC_METTL3_WT_vs_EV_F07.17542.17542.2 0.098 18-Jul K.IYVISLAEPR[166.11].L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1169.6684 1.63 59236 17542 2 1169.669276 585.8415 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3438.6 - 4.09E+06 - - - 0.766 - 1.866 0.239 - 160.9 2 2 0 0.0009 10 0 0 0 1.38E+08 8.48E+07 - - - 2.4127 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17543.17543.2 0.000594 20-Oct R.LYPVLQQSLVR.A sp|Q5RKV6|EXOS6_HUMAN 1 1314.766 0.91 59237 17543 2 1314.768806 658.3903 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.75 3438.7 - 835025 - - - 2.1555 - 1.644 0.473 - 400.2 1 2 0 0.0028 11 0 0 0 2.20E+07 2.40E+07 - - - 3.8785 1 230117_WJC_METTL3_WT_vs_EV_F07.17548.17548.2 1.11E-05 28-Dec R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 7.45 59242 17548 2 1494.908875 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3439.2 - 504839 - - - -4.8698 - 2.172 0.598 - 349.2 1 2 0 -0.0073 15 0 0 0 6.60E+07 8.86E+06 - - - 5.3625 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.17554.17554.2 0.0929 12-Jun K.FIDPFC[160.03]R[166.11].L sp|P56182|RRP1_HUMAN 1 963.4512 0.91 59246 17554 2 963.451094 482.7329 Ribosomal RNA processing protein 1 homolog A OS=Homo sapiens OX=9606 GN=RRP1 PE=1 SV=1 5.83 3439.9 - 1.36E+06 - - - -0.1028 - 1.063 0.353 - 97.8 1 2 0 -0.0001 7 0 0 0 1.65E+07 1.82E+07 - - - 1.8418 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.17555.17555.2 0.00855 12-Jun K.FIDPFC[160.03]R.L sp|P56182|RRP1_HUMAN 1 953.4429 0.91 59247 17555 2 953.442891 477.7287 Ribosomal RNA processing protein 1 homolog A OS=Homo sapiens OX=9606 GN=RRP1 PE=1 SV=1 5.83 3440 - 1.34E+06 - - - -0.0336 - 1.205 0.345 - 103.8 1 2 0 0 7 0 0 0 1.65E+07 1.82E+07 - - - 2.18 1 230117_WJC_METTL3_WT_vs_EV_F07.17563.17563.2 2.66E-05 18-Nov R.AAGVVLEMIR[166.11].E "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN,tr|M0QXI6|M0QXI6_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 4 1067.6037 1.77 59252 17563 2 1067.604415 534.8091 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6.05 3441 - 2.36E+06 - - - 0.6969 - 2.418 0.437 - 581.3 1 2 0 0.0007 10 0 0 0 4.71E+07 2.66E+07 - - - 4.733 0.9019 230117_WJC_METTL3_WT_vs_EV_F07.17567.17567.2 0.978 14-Jul R.LGFLLGEK.V "sp|Q9HCD6|TANC2_HUMAN,tr|J3KRP9|J3KRP9_HUMAN,tr|J3QQY7|J3QQY7_HUMAN,tr|J3KTM5|J3KTM5_HUMAN" 4 875.5117 1.02 59256 17567 2 875.515846 438.7631 Protein TANC2 OS=Homo sapiens OX=9606 GN=TANC2 PE=1 SV=3 6 3441.5 - 843612 - - - 4.7881 - 1.264 0.109 - 84.2 11 2 0 0.0042 8 0 0 0 6.50E+06 6.40E+06 - - - 0.0861 0.9569 230117_WJC_METTL3_WT_vs_EV_F07.17573.17573.2 0.000105 14-Sep K.FDTPFLPK.P sp|Q14684|RRP1B_HUMAN 1 963.5066 2.15 59260 17573 2 963.508929 482.7606 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 5.84 3442.2 - 1.99E+06 - - - 2.4494 - 1.592 0.411 - 198 1 1 0 0.0024 8 0 0 0 2.90E+08 1.35E+08 - - - 3.4783 0.9955 230117_WJC_METTL3_WT_vs_EV_F07.17579.17579.2 0.393 14-Jul R.GIFEPFGK.L "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 893.4647 0.84 59266 17579 2 893.46396 447.7396 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 6 3442.9 - 559475 - - - -0.8327 - 1.278 0.273 - 149 1 2 0 -0.0007 8 0 0 0 2.04E+08 2.45E+08 - - - 1.7969 0.9492 230117_WJC_METTL3_WT_vs_EV_F07.17580.17580.2 0.000559 20-Aug N.VPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1206.7104 7.21 59267 17580 2 1206.710073 604.3625 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.81 3443.1 - 349806 - - - -0.2387 - 1.631 0.434 - 162.6 1 1 0 -0.0003 11 0 0 0 1.35E+07 1.87E+06 - - - 3.5698 0.9683 230117_WJC_METTL3_WT_vs_EV_F07.17608.17608.2 0.0286 14-Oct Y.LDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 843.5066 771.98 59279 17608 2 843.507839 422.7606 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.84 3446.4 - 2.42E+06 - - - 1.5056 - 2.037 0.316 - 312.7 1 1 0 0.0013 8 0 0 0 3.11E+08 4.03E+05 - - - 3.5204 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17615.17615.2 0.009 16-Oct K.IAFAITAIK[136.11].G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 954.5994 1.18 59280 17615 2 954.602124 478.307 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3447.5 - 1.49E+07 - - - 2.9017 - 2.237 0.347 - 238.4 1 2 0 0.0028 9 0 0 0 1.37E+10 1.16E+10 - - - 3.9324 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.17620.17620.2 0.0107 13/20 R.MGPGIGAILER[166.11].S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1122.6095 3.15 59283 17620 2 1122.607099 562.312 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.75 3448 - 4.13E+06 - - - -2.1245 - 2.314 0.407 - 561.1 1 2 0 -0.0024 11 0 0 0 2.57E+08 8.18E+07 - - - 4.316 1 230117_WJC_METTL3_WT_vs_EV_F07.17628.17628.2 0.0149 14/18 N.PEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1087.5662 999 59284 17628 2 1087.568656 544.7904 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.43 3449.2 - 5.31E+06 - - - 2.25 - 2.561 0.451 - 805.1 1 1 0 0.0024 10 0 0 0 1.90E+08 0.00E+00 - - - 4.9963 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17636.17636.2 0.00847 16-Nov K.IAFAITAIK.G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 946.5852 1.18 59287 17636 2 946.585192 474.2999 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3450.3 - 6.45E+07 - - - 0.0401 - 2.252 0.336 - 331.5 1 2 0 0 9 0 0 0 1.37E+10 1.16E+10 - - - 3.8713 0.9955 230117_WJC_METTL3_WT_vs_EV_F07.17646.17646.2 0.0505 16-Oct K.SALLALGLK.C sp|Q12874|SF3A3_HUMAN 1 884.5695 3.55 59289 17646 2 884.567009 443.292 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3451.8 - 5.95E+06 - - - -2.8206 - 1.993 0.287 - 368.5 1 2 0 -0.0025 9 0 0 0 8.28E+08 2.33E+08 - - - 3.1552 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.17653.17653.2 0.0721 12-Aug K.ELEFYLR.K "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 968.4967 0.96 59291 17653 2 968.498245 485.2556 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.53 3452.7 - 2.43E+07 - - - 1.5612 - 1.568 0.157 - 437.6 1 2 0 0.0015 7 0 0 0 9.91E+08 1.04E+09 - - - 1.6253 0.996 230117_WJC_METTL3_WT_vs_EV_F07.17657.17657.2 0.0279 16-Sep K.SALLALGLK[136.11].C sp|Q12874|SF3A3_HUMAN 1 892.5837 3.55 59292 17657 2 892.581561 447.2991 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3453.2 - 2.48E+06 - - - -2.4009 - 2.005 0.26 - 290.7 1 2 0 -0.0021 9 0 0 0 8.28E+08 2.33E+08 - - - 2.9732 0.9895 230117_WJC_METTL3_WT_vs_EV_F07.17660.17660.2 0.0958 16-Oct K.YPQLLPGIR[166.11].G sp|P23526|SAHH_HUMAN 1 1065.621 0.86 59294 17660 2 1065.617567 533.8178 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 8.75 3453.6 - 0 - - - -3.2544 - 1.656 0.265 - 293.8 1 2 0 -0.0035 9 0 0 0 3.61E+07 4.21E+07 - - - 2.4565 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17667.17667.2 5.88E-05 18-Nov R.FQSLGVAFYR[166.11].G "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1196.6218 1.88 59296 17667 2 1196.624132 599.3182 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 8.75 3454.5 - 0 - - - 1.9789 - 2.122 0.412 - 362.1 1 2 0 0.0024 10 0 0 0 1.34E+08 7.11E+07 - - - 4.1834 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.17669.17669.2 0.00386 16-Aug K.ALQFLEEVK.V sp|P40227|TCPZ_HUMAN 1 1075.5914 999 59297 17669 2 1075.592111 538.803 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 3454.7 - 2.42E+06 - - - 0.6973 - 1.703 0.22 - 175.8 1 2 0 0.0008 9 0 0 0 9.44E+07 0.00E+00 - - - 2.2059 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17673.17673.2 0.000799 20-Oct K.FSPAGPILSIR[166.11].L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1166.6687 1.03 59299 17673 2 1166.671286 584.3416 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3455.1 - 1.80E+06 - - - 2.2046 - 1.93 0.323 - 402.6 1 2 0 0.0026 11 0 0 0 1.33E+09 1.29E+09 - - - 3.2046 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.17681.17681.2 0.00174 14-Sep K.IIDFGLAR.R "sp|Q86YV6|MYLK4_HUMAN,sp|Q32MK0|MYLK3_HUMAN,sp|Q9H1R3|MYLK2_HUMAN,sp|P53778|MK12_HUMAN,sp|O15264|MK13_HUMAN,sp|P45983|MK08_HUMAN,sp|Q16539|MK14_HUMAN,sp|P45984|MK09_HUMAN,sp|Q15759|MK11_HUMAN,sp|P53779|MK10_HUMAN,sp|Q15746|MYLK_HUMAN,tr|A0A286YFD7|A0A286YFD7_HUMAN,tr|A0A286YES0|A0A286YES0_HUMAN,tr|A0A286YEQ0|A0A286YEQ0_HUMAN,tr|A0A286YEX7|A0A286YEX7_HUMAN,tr|A0A286YFC0|A0A286YFC0_HUMAN,tr|B5MDL5|B5MDL5_HUMAN,tr|A0A286YES9|A0A286YES9_HUMAN,tr|A0A286YF97|A0A286YF97_HUMAN,tr|D6RCB1|D6RCB1_HUMAN,tr|A0A286YF19|A0A286YF19_HUMAN,tr|A0A286YFN2|A0A286YFN2_HUMAN,tr|D6RJF9|D6RJF9_HUMAN,tr|A0A286YEY0|A0A286YEY0_HUMAN,tr|Q5R3E6|Q5R3E6_HUMAN,tr|A0A286YEV8|A0A286YEV8_HUMAN,tr|B4E0K5|B4E0K5_HUMAN,tr|A0A286YF85|A0A286YF85_HUMAN,tr|A0A286YFI3|A0A286YFI3_HUMAN,tr|F8W9R5|F8W9R5_HUMAN,tr|A0A2R8Y4U5|A0A2R8Y4U5_HUMAN,tr|A0A286YFM6|A0A286YFM6_HUMAN,tr|A0A286YEV3|A0A286YEV3_HUMAN,tr|A0A286YF83|A0A286YF83_HUMAN,tr|A0A286YFJ6|A0A286YFJ6_HUMAN,tr|A0A286YF62|A0A286YF62_HUMAN,tr|A0A286YF02|A0A286YF02_HUMAN,tr|J3KNK1|J3KNK1_HUMAN,tr|A0A286YEQ7|A0A286YEQ7_HUMAN,tr|A0A286YFJ4|A0A286YFJ4_HUMAN,tr|A0A1W2PPZ3|A0A1W2PPZ3_HUMAN,tr|A0A286YEN5|A0A286YEN5_HUMAN,tr|A0A286YFA6|A0A286YFA6_HUMAN,tr|A0A1P0B7D2|A0A1P0B7D2_HUMAN,tr|A0A1W2PRF2|A0A1W2PRF2_HUMAN,tr|D7R525|D7R525_HUMAN,tr|A0A286YF35|A0A286YF35_HUMAN,tr|A0A286YFB6|A0A286YFB6_HUMAN,tr|A0A286YFE2|A0A286YFE2_HUMAN,tr|A0A286YEW9|A0A286YEW9_HUMAN,tr|E7EX54|E7EX54_HUMAN" 51 903.5178 4.3 59302 17681 2 903.517745 452.7662 Myosin light chain kinase family member 4 OS=Homo sapiens OX=9606 GN=MYLK4 PE=1 SV=2 5.84 3456.1 - 2.71E+06 - - - -0.0631 - 1.992 0.062 - 192.2 1 2 0 -0.0001 8 0 0 0 7.17E+07 1.67E+07 - - - 1.5773 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17683.17683.2 0.000437 20-Nov K.FSPAGPILSIR.L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1156.6604 1.03 59303 17683 2 1156.662982 579.3375 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3456.3 - 5.13E+06 - - - 2.1942 - 2.058 0.343 - 488.9 1 2 0 0.0025 11 0 0 0 1.33E+09 1.29E+09 - - - 3.5261 0.9723 230117_WJC_METTL3_WT_vs_EV_F07.17696.17696.2 2.35 14-Jul K.GLGILSLK[136.11].Q sp|Q92616|GCN1_HUMAN 1 807.5309 0.81 59309 17696 2 807.52891 404.7727 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.75 3458 - 0 - - - -2.5138 - 1.305 0.177 - 92.5 1 2 0 -0.002 8 0 0 0 4.78E+07 5.89E+07 - - - 1.1505 0.8873 230117_WJC_METTL3_WT_vs_EV_F07.17697.17697.2 0.141 16-Aug R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 8614.15 59310 17697 2 1014.57711 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3458.1 - 2.74E+06 - - - -6.8876 - 1.447 0.283 - 127.2 1 2 0 -0.007 9 0 0 0 7.17E+11 8.32E+07 - - - 2.198 0.9905 230117_WJC_METTL3_WT_vs_EV_F07.17700.17700.2 0.322 12-Jul K.FIPEFIR.K "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|A0A804HIK9|A0A804HIK9_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 5 920.512 0.76 59311 17700 2 920.514881 461.2633 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6 3458.5 - 1.34E+06 - - - 3.1417 - 1.358 0.136 - 163.3 1 2 0 0.0029 7 0 0 0 2.99E+07 3.95E+07 - - - 1.0142 1 230117_WJC_METTL3_WT_vs_EV_F07.17705.17705.2 8.93E-07 14/20 K.VLADLAIYEPK[136.11].T sp|Q9BYC9|RM20_HUMAN 1 1238.7002 1.24 59315 17705 2 1238.701423 620.3574 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3459.1 - 999632 - - - 0.9954 - 2.335 0.477 - 607.7 1 2 0 0.0012 11 0 0 0 4.43E+07 3.58E+07 - - - 4.8578 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.17708.17708.2 0.00101 18-Oct K.VGDQILLAIK[136.11].G sp|Q6P1L8|RM14_HUMAN 1 1076.6685 1.64 59316 17708 2 1076.667879 539.3415 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3459.5 - 2.78E+06 - - - -0.5731 - 1.531 0.365 - 179.3 1 2 0 -0.0006 10 0 0 0 1.60E+08 9.75E+07 - - - 2.9256 0.8761 230117_WJC_METTL3_WT_vs_EV_F07.17711.17711.2 0.0438 14-Jun R.GLFIIDGK.G sp|P32119|PRDX2_HUMAN 1 861.496 2.48 59319 17711 2 861.490034 431.7553 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3459.9 - 2.33E+06 - - - -6.9298 - 1.453 0.264 - 147.5 1 2 0 -0.006 8 0 0 0 8.34E+08 3.37E+08 - - - 2.1159 0.9965 230117_WJC_METTL3_WT_vs_EV_F07.17712.17712.2 0.0126 14-Jul R.GLFIIDGK[136.11].G sp|P32119|PRDX2_HUMAN 1 869.5102 2.46 59320 17712 2 869.508622 435.7624 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3460 - 1.59E+06 - - - -1.8194 - 1.432 0.345 - 182.6 1 2 0 -0.0016 8 0 0 0 8.29E+08 3.36E+08 - - - 2.6716 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17713.17713.2 4.14E-05 20-Nov K.LGNPIVPLNIR.L sp|P78527|PRKDC_HUMAN 1 1204.7292 0.73 59321 17713 2 1204.729055 603.3719 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3460.1 - 1.32E+06 - - - -0.1137 - 2.174 0.461 - 383.8 1 2 0 -0.0001 11 0 0 0 9.70E+06 1.33E+07 - - - 4.5467 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.17718.17718.2 3.39E-05 14-Oct R.GPIAFWAR.R "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H909|Q5H909_HUMAN" 2 916.4919 1.1 59324 17718 2 916.48958 459.2532 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 9.75 3460.8 - 2.04E+06 - - - -2.5554 - 1.933 0.44 - 463.8 1 2 0 -0.0023 8 0 0 0 7.34E+07 6.65E+07 - - - 4.2778 0.9673 230117_WJC_METTL3_WT_vs_EV_F07.17719.17719.2 0.567 12-Jul K.SLDIFIK.A sp|Q9H583|HEAT1_HUMAN 1 834.4851 0.45 59325 17719 2 834.488204 418.2498 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.55 3460.9 - 1.55E+06 - - - 3.7137 - 1.273 0.077 - 176.3 1 2 0 0.0031 7 0 0 0 2.87E+07 6.43E+07 - - - 0.3736 1 230117_WJC_METTL3_WT_vs_EV_F07.17723.17723.2 4.92E-05 18-Nov D.TLDNDIMLIK.L "sp|P35030|TRY3_HUMAN,tr|A0A7P0MNE9|A0A7P0MNE9_HUMAN" 2 1174.6268 21.65 59327 17723 2 1174.628544 588.3207 Trypsin-3 OS=Homo sapiens OX=9606 GN=PRSS3 PE=1 SV=2 4.21 3461.4 - 7.77E+06 - - - 1.5179 - 2.139 0.489 - 253.5 1 1 0 0.0018 10 0 0 0 1.31E+08 6.06E+06 - - - 4.7745 1 230117_WJC_METTL3_WT_vs_EV_F07.17724.17724.2 1.17E-05 18-Dec K.VGDQILLAIK.G sp|Q6P1L8|RM14_HUMAN 1 1068.6543 1.64 59328 17724 2 1068.650666 535.3344 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3461.5 - 3.29E+06 - - - -3.3968 - 2.477 0.537 - 553.5 1 2 0 -0.0036 10 0 0 0 1.60E+08 9.75E+07 - - - 5.538 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17727.17727.2 0.0112 16-Oct R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.88 59330 17727 2 989.59283 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3461.9 - 3.81E+06 - - - 1.8826 - 2.157 0.271 - 288.2 1 2 0 0.0019 9 0 0 0 3.49E+08 3.98E+08 - - - 3.266 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.17729.17729.2 0.0015 14-Sep R.GPIAFWAR[166.11].R "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H909|Q5H909_HUMAN" 2 926.5002 1.12 59331 17729 2 926.504442 464.2574 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 9.75 3462.1 - 1.80E+06 - - - 4.5872 - 2.029 0.381 - 379 1 2 0 0.0043 8 0 0 0 7.21E+07 6.42E+07 - - - 3.9876 1 230117_WJC_METTL3_WT_vs_EV_F07.17732.17732.2 7.21E-08 18-Dec K.LGDDIDLIVR.C sp|O15371|EIF3D_HUMAN 1 1127.6186 1.07 59332 17732 2 1127.613167 564.8166 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3462.5 - 1.93E+06 - - - -4.8527 - 2.479 0.498 - 427.2 1 2 0 -0.0055 10 0 0 0 4.97E+08 4.65E+08 - - - 5.2516 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17734.17734.2 0.0256 16-Oct R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 0.86 59334 17734 2 997.608081 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3462.6 - 3.50E+06 - - - 2.921 - 2.184 0.348 - 238.9 1 2 0 0.0029 9 0 0 0 3.58E+08 4.14E+08 - - - 3.8703 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.17735.17735.2 0.0506 18-Sep K.ALLAEGVILR.R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1053.6546 1.37 59335 17735 2 1053.657631 527.8346 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3462.8 - 1.45E+06 - - - 2.8482 - 1.917 0.278 - 192.4 1 2 0 0.003 10 0 0 0 4.26E+08 3.11E+08 - - - 2.9098 0.9939 230117_WJC_METTL3_WT_vs_EV_F07.17737.17737.2 0.179 14-Aug K.AFLNAIMR.Y "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|K7EMY3|K7EMY3_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 23 934.5059 0.88 59337 17737 2 934.507112 468.2602 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.79 3463 - 870629 - - - 1.343 - 1.314 0.13 - 121.7 1 2 0 0.0013 8 0 0 0 1.81E+07 2.06E+07 - - - 0.8244 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17739.17739.2 0.00106 20-Sep R.LLYC[160.03]TTGVLLR.R "sp|Q6P158|DHX57_HUMAN,sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 3 1307.7271 0.7 59339 17739 2 1307.726473 654.8708 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 8.22 3463.3 - 583420 - - - -0.5131 - 1.997 0.396 - 323 1 2 0 -0.0007 11 0 0 0 1.11E+07 1.59E+07 - - - 3.8367 0.9898 230117_WJC_METTL3_WT_vs_EV_F07.17742.17742.2 1.11 14-Sep R.NLLTGLVR[166.11].H "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 894.5526 1.21 59340 17742 2 894.552126 448.2836 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 9.75 3463.7 - 2.64E+06 - - - -0.5533 - 1.528 0.088 - 270.6 1 2 0 -0.0005 8 0 0 0 2.03E+08 1.68E+08 - - - 0.9695 1 230117_WJC_METTL3_WT_vs_EV_F07.17743.17743.2 0.000237 14/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 19.06 59341 17743 2 1484.915391 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3463.8 - 1.35E+06 - - - 5.0549 - 2.358 0.503 - 432.2 1 2 0 0.0075 15 0 0 0 7.57E+07 3.97E+06 - - - 4.8628 0.9951 230117_WJC_METTL3_WT_vs_EV_F07.17744.17744.2 1.4 13/18 K.ALLAEGVILR[166.11].R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1063.6629 1.37 59342 17744 2 1063.661929 532.8387 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3463.9 - 2.66E+06 - - - -0.9129 - 2.008 0.104 - 717.3 1 2 0 -0.001 10 0 0 0 4.26E+08 3.11E+08 - - - 1.7548 1 230117_WJC_METTL3_WT_vs_EV_F07.17750.17750.2 4.08E-06 18-Oct K.LGDDIDLIVR[166.11].C sp|O15371|EIF3D_HUMAN 1 1137.6269 1.07 59347 17750 2 1137.626756 569.8207 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3464.6 - 8.59E+06 - - - -0.1345 - 2.635 0.517 - 290.7 1 2 0 -0.0002 10 0 0 0 4.97E+08 4.65E+08 - - - 5.564 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.17752.17752.2 1.05 14-Sep R.NLLTGLVR.H "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 884.5444 1.17 59348 17752 2 884.543736 443.2795 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 9.75 3464.8 - 3.79E+06 - - - -0.6953 - 1.476 0.246 - 267.7 1 2 0 -0.0006 8 0 0 0 1.91E+08 1.63E+08 - - - 2.032 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.17753.17753.2 0.0832 14-Aug R.LLNVWQVR.S "sp|Q15061|WDR43_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 2 1026.5974 1.1 59349 17753 2 1026.596396 514.306 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 9.75 3464.9 - 2.02E+06 - - - -1.0267 - 1.687 0.243 - 227.5 1 2 0 -0.0011 8 0 0 0 1.07E+08 9.79E+07 - - - 2.4127 0.9952 230117_WJC_METTL3_WT_vs_EV_F07.17754.17754.2 0.159 12-Jun R.LFLEFER[166.11].K "sp|O43663|PRC1_HUMAN,sp|Q96I25|SPF45_HUMAN,tr|H0YL53|H0YL53_HUMAN" 3 962.5101 0.96 59350 17754 2 962.513033 482.2623 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 3464.9 - 1.74E+06 - - - 3.0597 - 1.447 0.176 - 106.9 1 2 0 0.0029 7 0 0 0 4.71E+07 4.92E+07 - - - 1.5108 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17755.17755.2 0.00917 18-Oct R.IAEFAFEYAR.N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1215.5924 2.24 59351 17755 2 1215.594274 608.8035 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3465.1 - 1.74E+06 - - - 1.5219 - 2.171 0.227 - 332.3 1 2 0 0.0019 10 0 0 0 6.36E+07 2.83E+07 - - - 2.8808 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.17756.17756.2 0.0458 20-Dec K.VLADLAIYEPK.T sp|Q9BYC9|RM20_HUMAN 1 1230.686 1.24 59352 17756 2 1230.6861 616.3503 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3465.2 - 1.46E+06 - - - 0.0894 - 2.057 0.269 - 285.3 1 2 0 0.0001 11 0 0 0 4.43E+07 3.58E+07 - - - 2.9789 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.17757.17757.2 0.131 18-Jun K.LLYPLQEVER[166.11].F "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 1268.7004 1.87 59353 17757 2 1268.703317 635.3575 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.53 3465.3 - 592405 - - - 2.2929 - 1.358 0.219 - 123.4 1 2 0 0.0029 10 0 0 0 1.06E+07 5.67E+06 - - - 1.5118 0.9921 230117_WJC_METTL3_WT_vs_EV_F07.17761.17761.2 0.177 14-Aug R.GLFIIDDK.G "sp|Q06830|PRDX1_HUMAN,sp|Q13162|PRDX4_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|H7C3T4|H7C3T4_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 5 919.5015 2.09 59355 17761 2 919.501914 460.758 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.21 3465.9 - 8.75E+06 - - - 0.4676 - 1.766 0.001 - 282.6 1 2 0 0.0004 8 0 0 0 3.14E+09 1.50E+09 - - - 0.7635 0.9949 230117_WJC_METTL3_WT_vs_EV_F07.17762.17762.2 0.134 12-Jun R.IIFDDFR[166.11].E sp|P46977|STT3A_HUMAN 1 934.4788 1.11 59356 17762 2 934.479756 468.2467 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.21 3465.9 - 2.62E+06 - - - 1.0359 - 1.079 0.229 - 89.4 1 2 0 0.001 7 0 0 0 2.83E+08 2.55E+08 - - - 0.973 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17764.17764.2 0.00056 14-Aug K.GFGFGLVK[136.11].L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 831.4734 1.22 59358 17764 2 831.473547 416.744 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3466 - 1.21E+06 - - - 0.1467 - 1.467 0.412 - 191 1 2 0 0.0001 8 0 0 0 5.57E+08 4.58E+08 - - - 3.2398 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17765.17765.2 9.16E-05 18-Dec R.IAEFAFEYAR[166.11].N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1225.6007 2.24 59359 17765 2 1225.602605 613.8076 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3466.2 - 853556 - - - 1.5592 - 2.389 0.242 - 625.1 1 2 0 0.0019 10 0 0 0 6.34E+07 2.83E+07 - - - 3.2587 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.17768.17768.2 5.06E-06 14/22 K.TPAILYTYSGLR.N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1353.7293 2.48 59362 17768 2 1353.730811 677.8719 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3466.6 - 416626 - - - 1.1516 - 2.921 0.36 - 831.6 1 2 0 0.0016 12 0 0 0 2.48E+07 1.00E+07 - - - 4.5199 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17770.17770.2 0.0101 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 8614.15 59363 17770 2 1006.572035 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3466.8 - 3.38E+08 - - - 2.1231 - 1.768 0.45 - 259.9 1 2 0 0.0021 9 0 0 0 7.17E+11 8.32E+07 - - - 4.0126 0.9938 230117_WJC_METTL3_WT_vs_EV_F07.17775.17775.2 0.0206 16-Sep R.ITELMQVLK[136.11].D "sp|P28288|ABCD3_HUMAN,tr|A0A3B3ITW3|A0A3B3ITW3_HUMAN" 2 1081.6297 0.54 59367 17775 2 1081.635759 541.8221 ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3 PE=1 SV=1 6 3467.4 - 542909 - - - 5.6313 - 1.949 0.277 - 141.2 1 2 0 0.0061 9 0 0 0 6.43E+06 1.19E+07 - - - 3.0156 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17776.17776.2 0.00107 20-Oct R.GILEGELEGIR.G "sp|O75600|KBL_HUMAN,tr|H7BZ75|H7BZ75_HUMAN,tr|F2Z340|F2Z340_HUMAN,tr|C9IZC9|C9IZC9_HUMAN" 4 1184.6401 8.02 59368 17776 2 1184.64138 593.3273 "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial OS=Homo sapiens OX=9606 GN=GCAT PE=1 SV=1" 4.25 3467.5 - 414600 - - - 1.0788 - 1.981 0.32 - 246.3 1 2 0 0.0013 11 0 0 0 9.74E+06 1.21E+06 - - - 3.2534 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17777.17777.2 0.000808 18-Nov R.LPLLAVC[160.03]DYK[136.11].Q "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1198.6511 0.75 59369 17777 2 1198.651812 600.3328 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.83 3467.6 - 355833 - - - 0.5673 - 2.199 0.325 - 400.3 1 2 0 0.0007 10 0 0 0 1.55E+07 2.05E+07 - - - 3.6408 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.17781.17781.2 0.545 16-Aug R.LNVLANVIR[166.11].K "sp|Q02218|ODO1_HUMAN,sp|Q9ULD0|OGDHL_HUMAN,tr|E9PFG7|E9PFG7_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|A0A0D9SFS3|A0A0D9SFS3_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 6 1020.6319 0.88 59371 17781 2 1020.634581 511.3232 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 9.75 3468.2 - 998163 - - - 2.5935 - 1.879 0.169 - 189.5 1 2 0 0.0026 9 0 0 0 1.85E+07 2.10E+07 - - - 2.1132 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.17782.17782.2 0.0035 18-Sep R.LPLLAVC[160.03]DYK.Q "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1190.6369 0.74 59372 17782 2 1190.635667 596.3257 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.83 3468.3 - 490409 - - - -1.0625 - 2.121 0.311 - 260.9 1 2 0 -0.0013 10 0 0 0 1.51E+07 2.05E+07 - - - 3.4364 1 230117_WJC_METTL3_WT_vs_EV_F07.17789.17789.2 1.71 14/22 K.TPAILYTYSGLR[166.11].N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1363.7375 2.48 59377 17789 2 1363.738158 682.876 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3469.1 - 601407 - - - 0.4664 - 3.141 0.394 - 834.9 1 2 0 0.0006 12 0 0 0 2.48E+07 1.00E+07 - - - 4.9624 0.9932 230117_WJC_METTL3_WT_vs_EV_F07.17792.17792.2 0.031 16-Sep R.ILLLNEMEK.L "sp|P35573|GDE_HUMAN,tr|A0A1C7CYW1|A0A1C7CYW1_HUMAN" 2 1101.6104 1.34 59378 17792 2 1101.607915 551.8125 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 4.53 3469.5 - 461621 - - - -2.2394 - 1.599 0.25 - 152.8 1 2 0 -0.0025 9 0 0 0 2.62E+07 1.96E+07 - - - 2.2447 0.8569 230117_WJC_METTL3_WT_vs_EV_F07.17795.17795.2 0.0285 18-Sep K.ILETLYTLGK.A "sp|Q5W0V3|FHI2A_HUMAN,tr|Q5W0V4|Q5W0V4_HUMAN" 2 1149.6645 999 59380 17795 2 1150.668507 575.8395 FHF complex subunit HOOK interacting protein 2A OS=Homo sapiens OX=9606 GN=FHIP2A PE=1 SV=1 6 3469.8 - 368492 - - - 873.2817 - 1.699 0.233 - 160.5 1 2 0 1.004 10 0 0 0 8.82E+06 0.00E+00 - - - 1.9262 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17799.17799.2 7.71E-05 14/22 K.LPVGTTATLYFR.D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1337.7343 1.17 59382 17799 2 1337.738087 669.8744 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3470.3 - 387193 - - - 2.8032 - 2.146 0.457 - 648.2 1 2 0 0.0037 12 0 0 0 2.04E+07 1.75E+07 - - - 4.4244 1 230117_WJC_METTL3_WT_vs_EV_F07.17805.17805.2 5.12E-05 13/22 K.LPVGTTATLYFR[166.11].D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1347.7426 1.17 59387 17805 2 1347.745619 674.8786 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3471 - 590057 - - - 2.2348 - 2.402 0.513 - 551.5 1 2 0 0.003 12 0 0 0 2.01E+07 1.73E+07 - - - 5.1348 0.991 230117_WJC_METTL3_WT_vs_EV_F07.17812.17812.2 0.0716 16-Aug R.ILLLNEMEK[136.11].L "sp|P35573|GDE_HUMAN,tr|A0A1C7CYW1|A0A1C7CYW1_HUMAN" 2 1109.6246 1.48 59392 17812 2 1109.627469 555.8196 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 4.53 3471.9 - 844197 - - - 2.6018 - 1.599 0.056 - 125 1 2 0 0.0029 9 0 0 0 2.62E+07 1.78E+07 - - - 0.8116 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17813.17813.2 0.00248 14-Aug K.GFGFGLVK.L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 823.4592 1.22 59393 17813 2 823.459938 412.7369 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3471.9 - 1.59E+07 - - - 0.8659 - 1.492 0.388 - 209.6 1 2 0 0.0007 8 0 0 0 5.58E+08 4.58E+08 - - - 3.1133 0.9895 230117_WJC_METTL3_WT_vs_EV_F07.17819.17819.2 0.0756 14-Jun K.TILSLMTR[166.11].E sp|P53396|ACLY_HUMAN 1 943.54 0.95 59397 17819 2 943.542306 472.7773 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.41 3472.7 - 3.88E+06 - - - 2.4355 - 1.32 0.103 - 115.2 1 2 0 0.0023 8 0 0 0 7.79E+07 8.20E+07 - - - 0.6384 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.17821.17821.2 0.0724 12-Jul K.GVIFYLR.D "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 9 866.5014 4.52 59399 17821 2 866.502486 434.258 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 8.75 3472.8 - 2.27E+06 - - - 1.2256 - 1.566 0.158 - 196.2 1 2 0 0.0011 7 0 0 0 1.26E+08 2.78E+07 - - - 1.6288 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.17822.17822.2 0.598 14-Aug K.ISALALLK[136.11].M sp|Q92905|CSN5_HUMAN 1 835.5622 1.31 59400 17822 2 835.562919 418.7884 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 8.75 3472.9 - 841147 - - - 0.8126 - 1.652 0.071 - 120.2 1 2 0 0.0007 8 0 0 0 3.58E+07 2.72E+07 - - - 1.0792 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17824.17824.2 3.22E-06 22-Nov R.LPVPESITGFAR.L "sp|Q8N5K1|CISD2_HUMAN,tr|I3L1N9|I3L1N9_HUMAN,tr|A0A2R8Y540|A0A2R8Y540_HUMAN" 3 1285.703 0.42 59402 17824 2 1285.703432 643.8588 CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1 6 3473.2 - 308684 - - - 0.3072 - 2.241 0.419 - 392.3 1 2 0 0.0004 12 0 0 0 5.72E+06 1.36E+07 - - - 4.2588 0.998 230117_WJC_METTL3_WT_vs_EV_F07.17825.17825.2 0.0418 22-Aug R.LPVPESITGFAR[166.11].L "sp|Q8N5K1|CISD2_HUMAN,tr|I3L1N9|I3L1N9_HUMAN,tr|A0A2R8Y540|A0A2R8Y540_HUMAN" 3 1295.7113 1.47 59403 17825 2 1295.713497 648.8629 CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1 6 3473.3 - 0 - - - 1.6902 - 1.342 0.262 - 145.6 1 2 0 0.0022 12 0 0 0 3.75E+06 2.56E+06 - - - 1.7494 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.17830.17830.2 0.00231 16-Aug K.MIFDVESMK[136.11].K sp|P09874|PARP1_HUMAN 1 1106.5232 0.93 59406 17830 2 1106.523158 554.2689 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.37 3474 - 1.07E+06 - - - 0.0036 - 1.566 0.364 - 169.3 1 2 0 0 9 0 0 0 2.65E+07 2.84E+07 - - - 3.0271 0.8639 230117_WJC_METTL3_WT_vs_EV_F07.17833.17833.2 1.12 12-Jun K.AYLFQLR.L "sp|O14681|EI24_HUMAN,tr|B7ZB74|B7ZB74_HUMAN" 2 909.5072 999 59409 17833 2 909.51164 455.7609 Etoposide-induced protein 2.4 homolog OS=Homo sapiens OX=9606 GN=EI24 PE=1 SV=4 8.79 3474.4 - 409132 - - - 4.84 - 1.299 0 - 89.3 1 2 0 0.0044 7 0 0 0 5.45E+06 0.00E+00 - - - -0.1315 0.9866 230117_WJC_METTL3_WT_vs_EV_F07.17837.17837.2 0.353 12-Jul K.FIGELFK[136.11].L "sp|O43432|IF4G3_HUMAN,sp|Q04637|IF4G1_HUMAN,tr|A0A804HJV5|A0A804HJV5_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|A0A0U1RQK7|A0A0U1RQK7_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|A0A0A0MSA7|A0A0A0MSA7_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 11 860.4887 0.17 59411 17837 2 860.492474 431.2516 Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2 6 3474.9 - 3.35E+06 - - - 4.3382 - 1.371 0.179 - 124.6 1 2 0 0.0037 7 0 0 0 6.41E+07 3.74E+08 - - - 1.3617 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.17839.17839.2 0.0014 16-Sep K.FPTLWSGAR.S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1033.5345 0.96 59413 17839 2 1033.536828 517.7745 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 9.75 3475 - 2.45E+06 - - - 2.238 - 1.714 0.307 - 359.8 1 2 0 0.0023 9 0 0 0 1.47E+08 1.53E+08 - - - 2.8666 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17840.17840.2 0.00083 16-Oct R.LIDFLESGK.T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1020.5492 1.29 59414 17840 2 1020.548952 511.2819 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3475.1 - 1.58E+06 - - - -0.2058 - 1.861 0.361 - 238.5 1 2 0 -0.0002 9 0 0 0 2.51E+08 1.94E+08 - - - 3.5042 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.17843.17843.2 0.00171 18-Sep K.WSEALVLYDR[166.11].V sp|Q9UHB9|SRP68_HUMAN 1 1260.6378 1.17 59417 17843 2 1260.643298 631.3262 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.37 3475.4 - 285453 - - - 4.3549 - 1.964 0.44 - 337.4 1 2 0 0.0055 10 0 0 0 8.99E+06 7.71E+06 - - - 4.1732 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.17844.17844.2 0.00255 20-Nov K.SEIEYYAMLAK[136.11].T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1324.6464 1.1 59418 17844 2 1324.653181 663.3305 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3475.5 - 273671 - - - 5.0889 - 2.074 0.387 - 428.6 1 2 0 0.0067 11 0 0 0 1.44E+07 1.31E+07 - - - 3.8707 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.17848.17848.2 0.00388 16-Sep R.LIDFLESGK[136.11].T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1028.5634 1.3 59420 17848 2 1028.563582 515.289 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3476.1 - 2.78E+06 - - - 0.2139 - 1.71 0.353 - 165 1 2 0 0.0002 9 0 0 0 2.57E+08 1.97E+08 - - - 3.2003 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17849.17849.2 0.0282 20-Dec R.ELLIIGGVAAR[166.11].D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1120.6844 1.13 59421 17849 2 1120.686806 561.3495 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3476.2 - 1.62E+06 - - - 2.179 - 2.43 0.295 - 510.1 1 2 0 0.0024 11 0 0 0 3.20E+08 2.82E+08 - - - 3.6211 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17850.17850.2 0.000102 16-Sep K.FPTLWSGAR[166.11].S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1043.5428 1.12 59422 17850 2 1043.544809 522.7787 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 9.75 3476.3 - 2.47E+06 - - - 1.9395 - 1.936 0.31 - 354 1 2 0 0.002 9 0 0 0 2.26E+08 2.02E+08 - - - 3.2412 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17851.17851.2 0.123 20-Nov R.ELLIIGGVAAR.D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1110.6761 1.11 59423 17851 2 1110.677668 556.3453 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3476.4 - 1.53E+06 - - - 1.4172 - 2.19 0.309 - 352.8 1 2 0 0.0016 11 0 0 0 3.20E+08 2.88E+08 - - - 3.4434 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.17856.17856.2 0.027 16-Nov R.LAVLPYELR.F "sp|Q9ULX3|NOB1_HUMAN,tr|H3BUR4|H3BUR4_HUMAN" 2 1072.6281 1.24 59426 17856 2 1072.630476 537.3213 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 6 3477 - 2.40E+06 - - - 2.2328 - 2.169 0.207 - 616.3 1 2 0 0.0024 9 0 0 0 2.04E+08 1.65E+08 - - - 2.8091 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17857.17857.2 0.00127 20-Oct K.SEIEYYAMLAK.T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1316.6322 0.94 59427 17857 2 1316.63605 659.3234 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3477.2 - 309777 - - - 2.8937 - 2.136 0.405 - 340.1 1 2 0 0.0038 11 0 0 0 1.46E+07 1.56E+07 - - - 4.0842 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.17858.17858.2 0.507 14-Sep K.IYQVLDFR.L "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1052.5655 1.65 59428 17858 2 1052.567708 527.29 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 5.84 3477.2 - 2.35E+06 - - - 2.1158 - 1.828 0.199 - 306.5 1 2 0 0.0022 8 0 0 0 6.39E+07 3.88E+07 - - - 2.3294 0.999 230117_WJC_METTL3_WT_vs_EV_F07.17859.17859.2 0.0406 16-Aug R.AVDVGAFLR[166.11].D "sp|Q96BT3|CENPT_HUMAN,tr|H3BUW2|H3BUW2_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 3 956.5319 0.93 59429 17859 2 956.533501 479.2732 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 5.88 3477.3 - 983471 - - - 1.6884 - 1.748 0.239 - 136.4 1 2 0 0.0016 9 0 0 0 4.42E+07 4.76E+07 - - - 2.4214 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.17864.17864.2 0.0192 14-Sep K.IYQVLDFR[166.11].L "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1062.5738 1.93 59432 17864 2 1062.577751 532.2942 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 5.84 3478 - 1.41E+06 - - - 3.7644 - 1.908 0.299 - 291.6 1 2 0 0.004 8 0 0 0 7.95E+07 4.12E+07 - - - 3.1966 0.999 230117_WJC_METTL3_WT_vs_EV_F07.17867.17867.2 0.0401 18-Aug K.WELNPEIVAR.H sp|Q9BYD2|RM09_HUMAN 1 1225.6455 1.02 59435 17867 2 1225.645902 613.83 "39S ribosomal protein L9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL9 PE=1 SV=2" 4.53 3478.3 - 331192 - - - 0.31 - 1.772 0.275 - 196.4 1 2 0 0.0004 10 0 0 0 6.45E+06 6.30E+06 - - - 2.669 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.17871.17871.2 0.0144 16-Aug R.AVDVGAFLR.D "sp|Q96BT3|CENPT_HUMAN,tr|H3BUW2|H3BUW2_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 3 946.5236 0.94 59437 17871 2 946.523586 474.2691 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 5.88 3478.9 - 1.21E+06 - - - -0.0317 - 1.674 0.324 - 173.8 1 2 0 0 9 0 0 0 4.32E+07 4.60E+07 - - - 2.9246 0.9924 230117_WJC_METTL3_WT_vs_EV_F07.17878.17878.2 0.0922 14-Aug R.GIFPVLC[160.03]K[136.11].D "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 940.5296 2.56 59442 17878 2 940.533628 471.2721 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 8.22 3479.7 - 1.26E+06 - - - 4.3252 - 1.41 0.24 - 199.6 1 2 0 0.0041 8 0 0 0 8.79E+07 3.43E+07 - - - 1.8486 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17885.17885.2 0.00467 16-Oct K.VNIIPIIAK[136.11].A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 987.6572 1.06 59447 17885 2 987.659631 494.8359 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3480.5 - 1.14E+06 - - - 2.4583 - 1.779 0.417 - 315.6 1 2 0 0.0024 9 0 0 0 6.89E+07 6.53E+07 - - - 3.7867 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.17886.17886.2 0.049 16-Jul K.VNIIPIIAK.A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 979.643 1.06 59448 17886 2 979.646074 490.8288 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3480.6 - 1.07E+06 - - - 3.1348 - 1.375 0.287 - 149.2 1 2 0 0.0031 9 0 0 0 6.89E+07 6.53E+07 - - - 2.0811 0.9922 230117_WJC_METTL3_WT_vs_EV_F07.17891.17891.2 0.126 12-Jun R.ISPWLLR.V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 883.528 0.36 59451 17891 2 883.530511 442.7713 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3481.3 - 1.63E+06 - - - 2.8726 - 1.368 0.154 - 116.7 2 2 0 0.0025 7 0 0 0 6.85E+07 1.90E+08 - - - 1.036 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17897.17897.2 0.0101 22-Nov K.VFNIYTDATPLR[166.11].V sp|Q8N8A6|DDX51_HUMAN 1 1418.7433 1.35 59455 17897 2 1418.747527 710.3789 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 5.81 3482.1 - 123430 - - - 2.9547 - 2.152 0.374 - 254.5 1 2 0 0.0042 12 0 0 0 3.01E+06 2.24E+06 - - - 3.8186 0.9937 230117_WJC_METTL3_WT_vs_EV_F07.17910.17910.2 0.0485 14-Aug K.WLTLEVC[160.03]R.E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1075.5485 1.6 59463 17910 2 1075.552093 538.7815 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3483.6 - 5.46E+06 - - - 3.3862 - 1.385 0.194 - 261.3 1 2 0 0.0036 8 0 0 0 9.10E+07 5.68E+07 - - - 1.455 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17918.17918.2 0.0193 20-Nov R.YIVQVSPLGIR.L sp|Q10570|CPSF1_HUMAN 1 1243.7289 1.44 59469 17918 2 1243.731268 622.8717 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3484.6 - 759962 - - - 1.9377 - 1.991 0.383 - 465.3 1 2 0 0.0024 11 0 0 0 2.86E+07 1.99E+07 - - - 3.732 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.17920.17920.2 0.0226 20-Jul K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.56 59471 17920 2 1235.763474 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3484.8 - 221205 - - - 2.6834 - 1.564 0.293 - 85.9 1 2 0 0.0033 11 0 0 0 6.02E+06 3.87E+06 - - - 2.414 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.17925.17925.2 0.176 14-Jul R.DILIDPIR[166.11].V "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 963.5629 1.71 59474 17925 2 963.564858 482.7887 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3485.6 - 335758 - - - 2.0819 - 1.398 0.22 - 164.6 1 2 0 0.002 8 0 0 0 4.51E+07 2.64E+07 - - - 1.6758 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.17927.17927.2 0.07 12-Jul R.YLNFFTK[136.11].A sp|P12004|PCNA_HUMAN 1 939.4946 1.42 59476 17927 2 939.496133 470.7546 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3485.8 - 964416 - - - 1.6807 - 1.338 0.212 - 139.1 1 2 0 0.0016 7 0 0 0 1.26E+08 8.88E+07 - - - 1.5289 0.9961 230117_WJC_METTL3_WT_vs_EV_F07.17928.17928.2 0.02 20-Aug K.FSPAGPILSIR[166.11].L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1166.6687 1.03 59477 17928 2 1166.672281 584.3416 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3485.9 - 370063 - - - 3.0574 - 1.409 0.234 - 126.4 1 2 0 0.0036 11 0 0 0 1.34E+09 1.30E+09 - - - 1.6958 0.9597 230117_WJC_METTL3_WT_vs_EV_F07.17933.17933.2 0.454 14-Sep S.PLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 906.5526 1.21 59480 17933 2 906.554452 454.2836 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 10.18 3486.6 - 937081 - - - 2.0197 - 1.949 0.305 - 325.2 1 1 0 0.0018 8 0 0 0 1.06E+08 8.74E+07 - - - 3.3058 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.17935.17935.2 0.134 12-Jun R.YLNFFTK.A sp|P12004|PCNA_HUMAN 1 931.4804 1.39 59482 17935 2 931.482336 466.7475 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3486.8 - 1.43E+06 - - - 2.1278 - 1.242 0.263 - 91 1 2 0 0.002 7 0 0 0 1.23E+08 8.87E+07 - - - 1.6696 1 230117_WJC_METTL3_WT_vs_EV_F07.17942.17942.2 2.81E-06 30-Nov R.VINEPTAAALAYGLDK.S "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1644.8723 53.66 59489 17942 2 1644.87778 823.4434 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3487.7 - 309627 - - - 3.3395 - 2.733 0.529 - 362.8 1 2 0 0.0055 16 0 0 0 1.19E+07 2.22E+05 - - - 5.4183 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.17943.17943.2 0.00199 20-Sep K.FSPAGPILSIR.L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1156.6604 1.03 59490 17943 2 1156.664541 579.3375 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3487.8 - 290569 - - - 3.5421 - 1.554 0.311 - 185.9 1 2 0 0.0041 11 0 0 0 1.33E+09 1.29E+09 - - - 2.5293 1 230117_WJC_METTL3_WT_vs_EV_F07.17948.17948.2 4.68E-06 20-Dec R.IVLLDSSLEYK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1278.7071 10.78 59493 17948 2 1278.710317 640.3608 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3488.4 - 2.78E+06 - - - 2.501 - 2.531 0.536 - 475 1 2 0 0.0032 11 0 0 0 2.98E+09 2.76E+08 - - - 5.511 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.17949.17949.2 0.152 14-Jul R.DILIDPIR.V "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 953.5546 1.7 59494 17949 2 953.556786 477.7846 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3488.5 - 2.17E+06 - - - 2.3114 - 1.318 0.335 - 205 1 2 0 0.0022 8 0 0 0 4.52E+07 2.66E+07 - - - 2.3474 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17950.17950.2 0.0277 14-Oct K.WLTLEVC[160.03]R[166.11].E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1085.5567 1.6 59495 17950 2 1085.558662 543.7856 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3488.6 - 2.16E+06 - - - 1.788 - 2.014 0.296 - 498 1 2 0 0.0019 8 0 0 0 9.04E+07 5.66E+07 - - - 3.3382 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.17951.17951.2 0.177 14-Jul R.AFFSSYLK.S "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 961.4909 0.69 59496 17951 2 961.493091 481.7527 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.63 3488.6 - 1.39E+06 - - - 2.259 - 1.235 0.286 - 144.2 1 2 0 0.0022 8 0 0 0 3.61E+07 5.23E+07 - - - 1.7893 1 230117_WJC_METTL3_WT_vs_EV_F07.17952.17952.2 1.01E-07 22-Dec R.VFIGNLNTALVK[136.11].K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1295.7693 0.5 59497 17952 2 1295.77183 648.8919 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3488.7 - 1.32E+06 - - - 1.9733 - 2.455 0.584 - 417.2 1 2 0 0.0026 12 0 0 0 7.06E+07 1.42E+08 - - - 5.7167 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17953.17953.2 0.00262 20-Nov K.LASDAGIFFTR.A "sp|Q9NR46|SHLB2_HUMAN,tr|G5E9J1|G5E9J1_HUMAN,tr|F8WFB9|F8WFB9_HUMAN,tr|B7ZC39|B7ZC39_HUMAN,tr|B7ZC38|B7ZC38_HUMAN" 5 1196.619 1.87 59498 17953 2 1196.622557 599.3168 Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2 PE=1 SV=1 5.84 3488.8 - 1.23E+06 - - - 2.9951 - 2.428 0.362 - 359.1 1 2 0 0.0036 11 0 0 0 1.65E+07 8.80E+06 - - - 4.1133 1 230117_WJC_METTL3_WT_vs_EV_F07.17954.17954.2 1.31E-05 22-Oct R.VFIGNLNTALVK.K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1287.7551 0.5 59499 17954 2 1287.764152 644.8848 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3488.9 - 970977 - - - 7.0503 - 2.223 0.495 - 273.9 1 2 0 0.0091 12 0 0 0 7.06E+07 1.42E+08 - - - 4.7961 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17955.17955.2 0.000308 16-Sep R.FLVQLDDYR.F "sp|Q9HAD4|WDR41_HUMAN,tr|D6RE66|D6RE66_HUMAN,tr|B4DK73|B4DK73_HUMAN,tr|D6RH33|D6RH33_HUMAN,tr|D6RA22|D6RA22_HUMAN,tr|B4DHS8|B4DHS8_HUMAN,tr|D6R9E7|D6R9E7_HUMAN,tr|H0YAA3|H0YAA3_HUMAN,tr|D6RBY6|D6RBY6_HUMAN,tr|H0YAI6|H0YAI6_HUMAN,tr|D6RB94|D6RB94_HUMAN" 11 1167.5924 1.33 59500 17955 2 1167.595007 584.8035 WD repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=WDR41 PE=1 SV=3 4.21 3489.1 - 807208 - - - 2.2122 - 1.908 0.397 - 337.1 1 2 0 0.0026 9 0 0 0 9.99E+06 7.49E+06 - - - 3.8415 1 230117_WJC_METTL3_WT_vs_EV_F07.17957.17957.2 0.000228 18-Nov K.IIQLLDDYPK.C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1216.6703 1.01 59502 17957 2 1216.674226 609.3424 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3489.3 - 543780 - - - 3.194 - 2.433 0.523 - 348.5 1 2 0 0.0039 10 0 0 0 6.20E+08 6.13E+08 - - - 5.3845 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.17958.17958.2 0.000358 16-Sep R.FLVQLDDYR[166.11].F "sp|Q9HAD4|WDR41_HUMAN,tr|D6RE66|D6RE66_HUMAN,tr|B4DK73|B4DK73_HUMAN,tr|D6RH33|D6RH33_HUMAN,tr|D6RA22|D6RA22_HUMAN,tr|B4DHS8|B4DHS8_HUMAN,tr|D6R9E7|D6R9E7_HUMAN,tr|H0YAA3|H0YAA3_HUMAN,tr|D6RBY6|D6RBY6_HUMAN,tr|H0YAI6|H0YAI6_HUMAN,tr|D6RB94|D6RB94_HUMAN" 11 1177.6007 1.33 59503 17958 2 1177.607066 589.8076 WD repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=WDR41 PE=1 SV=3 4.21 3489.5 - 523220 - - - 5.411 - 1.825 0.476 - 288 1 2 0 0.0064 9 0 0 0 9.99E+06 7.49E+06 - - - 4.2951 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.17959.17959.2 2.35E-05 28-Oct R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 7.03 59504 17959 2 1494.914203 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3489.6 - 377663 - - - -1.3058 - 1.996 0.486 - 259.2 1 2 0 -0.002 15 0 0 0 3.71E+07 5.28E+06 - - - 4.3292 1 230117_WJC_METTL3_WT_vs_EV_F07.17963.17963.2 5.31E-05 20-Dec K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 11.65 59506 17963 2 1204.686156 603.3481 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3490 - 1.03E+07 - - - 3.8043 - 2.506 0.541 - 619.9 1 2 0 0.0046 11 0 0 0 2.64E+09 2.26E+08 - - - 5.5207 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.17968.17968.2 1.31 14-Oct R.IVEVLLIK.D "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 925.6212 1.13 59511 17968 2 925.623184 463.8179 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6 3490.4 - 1.13E+06 - - - 2.138 - 1.904 0.372 - 239.8 1 2 0 0.002 8 0 0 0 3.29E+07 2.90E+07 - - - 3.7301 0.9761 230117_WJC_METTL3_WT_vs_EV_F07.17969.17969.2 0.0541 Jul-32 R.ASSGGGAGGAAGYAPVK.Y sp|P25067|CO8A2_HUMAN 1 1376.6684 2.81 59512 17969 2 1376.667179 689.3415 Collagen alpha-2(VIII) chain OS=Homo sapiens OX=9606 GN=COL8A2 PE=1 SV=2 8.63 3490.5 - 840419 - - - -0.9174 - 1.316 0.108 - 63 1 2 0 -0.0013 17 0 0 0 6.31E+07 2.24E+07 - - - 0.5134 1 230117_WJC_METTL3_WT_vs_EV_F07.17977.17977.2 0.00452 18-Nov K.IIQLLDDYPK[136.11].C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1224.6845 1.01 59519 17977 2 1224.685943 613.3495 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3491.5 - 7.29E+06 - - - 1.1456 - 2.47 0.428 - 401.7 1 2 0 0.0014 10 0 0 0 6.20E+08 6.13E+08 - - - 4.7257 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.17978.17978.2 1.28 12-Aug R.WLITLNK.Q "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 886.5276 1.15 59520 17978 2 886.528404 444.2711 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 8.75 3491.6 - 4.08E+06 - - - 0.8629 - 1.536 0.161 - 267.1 1 2 0 0.0008 7 0 0 0 3.65E+08 3.19E+08 - - - 1.5898 0.9874 230117_WJC_METTL3_WT_vs_EV_F07.17983.17983.2 3.64 18-Jul K.LAIWEASLDK.F "sp|Q9NWS8|RMND1_HUMAN,tr|A0A804HHW6|A0A804HHW6_HUMAN,tr|A0A804HHY2|A0A804HHY2_HUMAN,tr|A0A087WXU0|A0A087WXU0_HUMAN,tr|A0A2R8Y4J4|A0A2R8Y4J4_HUMAN,tr|A0A804HKF8|A0A804HKF8_HUMAN,tr|A0A804HLE1|A0A804HLE1_HUMAN" 7 1144.6128 0.75 59525 17983 2 1144.613116 573.3137 Required for meiotic nuclear division protein 1 homolog OS=Homo sapiens OX=9606 GN=RMND1 PE=1 SV=2 4.37 3492 - 300315 - - - 0.2542 - 1.209 0.125 - 85.3 1 2 0 0.0003 10 0 0 0 3.80E+06 5.07E+06 - - - 0.4939 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.17987.17987.3 0.0108 Dec-40 K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 10.67 59527 17987 3 1204.682126 402.5678 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3492.5 - 3.76E+06 - - - 0.459 - 1.794 0.314 - 139.7 1 2 0 0.0006 11 0 0 0 8.02E+07 7.52E+06 - - - 3.701 1 230117_WJC_METTL3_WT_vs_EV_F07.17989.17989.2 2.97E-06 18-Oct R.LMDEAVLALR.N sp|Q92616|GCN1_HUMAN 1 1129.6165 0.59 59529 17989 2 1129.621129 565.8155 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 3492.7 - 1.10E+06 - - - 4.0713 - 1.989 0.529 - 290.8 1 2 0 0.0046 10 0 0 0 1.31E+07 2.23E+07 - - - 4.8661 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.17990.17990.2 0.342 16-Jun R.GAGWLFGAK[136.11].V sp|O00743|PPP6_HUMAN 1 913.4901 2.34 59530 17990 2 913.491413 457.7523 Serine\threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1 8.75 3492.8 - 1.07E+06 - - - 1.3957 - 1.208 0.268 - 102.5 2 2 0 0.0013 9 0 0 0 3.70E+07 1.58E+07 - - - 1.4323 0.9881 230117_WJC_METTL3_WT_vs_EV_F07.17992.17992.2 0.0192 18-Aug K.LADQIFAYYK[136.11].V "sp|Q7L576|CYFP1_HUMAN,sp|Q96F07|CYFP2_HUMAN,tr|A0A0G2JR96|A0A0G2JR96_HUMAN,tr|E7EW33|E7EW33_HUMAN,tr|H7C229|H7C229_HUMAN,tr|E7EVJ5|E7EVJ5_HUMAN,tr|A0A0G2JQT1|A0A0G2JQT1_HUMAN" 7 1238.6427 0.74 59532 17992 2 1238.638352 620.3286 Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens OX=9606 GN=CYFIP1 PE=1 SV=1 5.83 3493.1 - 583615 - - - -3.4901 - 1.896 0.223 - 128.5 1 2 0 -0.0043 10 0 0 0 3.79E+06 5.10E+06 - - - 2.4724 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.17995.17995.2 0.000772 16-Sep K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 0.85 59533 17995 2 983.57654 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 3493.5 - 2.54E+06 - - - 0.1627 - 2.092 0.363 - 310.7 1 2 0 0.0002 9 0 0 0 4.50E+07 5.31E+07 - - - 3.8575 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.17998.17998.2 0.00426 16-Aug R.GAGWLFGAK.V sp|O00743|PPP6_HUMAN 1 905.4759 2.16 59536 17998 2 905.475776 453.7452 Serine\threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1 8.75 3493.7 - 2.86E+06 - - - -0.1789 - 1.25 0.302 - 146.2 1 2 0 -0.0002 9 0 0 0 3.35E+07 1.55E+07 - - - 1.9171 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.18002.18002.2 3.73 12-Aug R.WLITLNK[136.11].Q "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 894.5418 1.15 59539 18002 2 894.54225 448.2782 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 8.75 3494.2 - 1.42E+07 - - - 0.4595 - 1.633 0.151 - 375.5 1 2 0 0.0004 7 0 0 0 3.62E+08 3.15E+08 - - - 1.7101 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18004.18004.2 0.00384 16-Nov K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 0.87 59540 18004 2 993.586171 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 3494.4 - 2.13E+06 - - - 1.5308 - 2.268 0.311 - 510.7 1 2 0 0.0015 9 0 0 0 5.45E+07 6.25E+07 - - - 3.7067 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.18006.18006.2 0.0452 16-Jul K.AENPYLFLR.G "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN" 2 1121.5869 1.28 59542 18006 2 1121.589629 561.8007 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 6.05 3494.5 - 1.35E+06 - - - 2.393 - 1.329 0.276 - 157 1 2 0 0.0027 9 0 0 0 1.75E+07 1.37E+07 - - - 1.9016 1 230117_WJC_METTL3_WT_vs_EV_F07.18015.18015.2 1.38E-07 18-Nov R.EC[160.03]LNLWGYER.V sp|Q86U44|MTA70_HUMAN 1 1338.6027 38.69 59549 18015 2 1338.609239 670.3086 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3495.6 - 1.11E+06 - - - 4.9066 - 2.043 0.574 - 649.6 1 2 0 0.0066 10 0 0 0 1.11E+08 2.88E+06 - - - 5.2727 0.9462 230117_WJC_METTL3_WT_vs_EV_F07.18016.18016.2 1.6 14-Jul R.AFFSSYLK[136.11].S "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 969.5051 0.82 59550 18016 2 969.50812 485.7598 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.63 3495.7 - 1.08E+06 - - - 3.0954 - 1.092 0.063 - 111.5 1 2 0 0.003 8 0 0 0 3.60E+07 4.39E+07 - - - -0.2292 0.9945 230117_WJC_METTL3_WT_vs_EV_F07.18018.18018.3 0.0543 Oct-40 K.FATEAAITILR[166.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1214.6898 10.67 59552 18018 3 1214.687044 405.9039 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3495.9 - 737327 - - - -2.3043 - 1.885 0.258 - 80.7 1 2 0 -0.0028 11 0 0 0 8.02E+07 7.52E+06 - - - 3.2166 0.8961 230117_WJC_METTL3_WT_vs_EV_F07.18024.18024.2 0.982 18-Jun K.SFIMSSTLIR.H sp|Q9UEG4|ZN629_HUMAN 1 1153.6165 1.41 59556 18024 2 1153.614882 577.8155 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.47 3496.7 - 1.28E+06 - - - -1.4286 - 1.086 0.101 - 88.4 5 2 0 -0.0016 10 0 0 0 1.27E+07 9.00E+06 - - - -0.2955 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18025.18025.2 0.124 18-Oct K.SFIMSSTLIR[166.11].H sp|Q9UEG4|ZN629_HUMAN 1 1163.6248 1.41 59557 18025 2 1163.626665 582.8197 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.47 3496.8 - 727396 - - - 1.6028 - 1.797 0.346 - 312.3 1 2 0 0.0019 10 0 0 0 1.27E+07 9.00E+06 - - - 3.232 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.18027.18027.3 0.346 Nov-36 R.FSVLLLHGIR[166.11].F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1163.7054 2.49 59559 18027 3 1163.705702 388.9091 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3497.1 - 688402 - - - 0.2303 - 2.061 0.201 - 94.8 1 2 0 0.0003 10 0 0 0 1.62E+07 6.51E+06 - - - 2.8929 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.18028.18028.2 0.361 14-Aug R.VLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 815.4753 0.31 59560 18028 2 815.476015 408.7449 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 3497.2 - 556260 - - - 0.9148 - 1.379 0.287 - 194.3 1 2 0 0.0007 8 0 0 0 8.58E+06 2.77E+07 - - - 2.1298 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18031.18031.2 0.00671 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 999 59562 18031 2 1006.570834 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3497.5 - 3.46E+07 - - - 0.9299 - 1.933 0.48 - 254.4 1 2 0 0.0009 9 0 0 0 7.93E+08 0.00E+00 - - - 4.4927 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.18033.18033.3 0.0141 15/36 R.FSVLLLHGIR.F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1153.6972 2.49 59563 18033 3 1153.696594 385.573 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3497.7 - 1.83E+06 - - - -0.4941 - 2.513 0.436 - 264.4 1 2 0 -0.0006 10 0 0 0 1.62E+07 6.51E+06 - - - 6.0919 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.18034.18034.2 0.0381 14-Aug R.NILIVLTK[136.11].L "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN,tr|H0Y815|H0Y815_HUMAN" 3 920.615 0.82 59564 18034 2 920.616053 461.3148 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 8.75 3497.9 - 1.37E+06 - - - 1.1395 - 1.428 0.296 - 155.3 1 2 0 0.001 8 0 0 0 1.25E+07 1.52E+07 - - - 2.3014 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.18035.18035.2 1.52 16-Jul K.AAIDWFDGK.E "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1021.4869 1.17 59565 18035 2 1021.490096 511.7507 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.21 3497.9 - 1.28E+06 - - - 3.1327 - 1.368 0.278 - 113.3 1 2 0 0.0032 9 0 0 0 1.20E+07 1.02E+07 - - - 1.9998 0.9891 230117_WJC_METTL3_WT_vs_EV_F07.18036.18036.2 0.197 14-Sep R.NILIVLTK.L "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN,tr|H0Y815|H0Y815_HUMAN" 3 912.6008 0.81 59566 18036 2 912.601549 457.3077 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 8.75 3498.1 - 1.07E+06 - - - 0.8163 - 1.415 0.05 - 233.3 1 2 0 0.0007 8 0 0 0 1.26E+07 1.55E+07 - - - 0.457 1 230117_WJC_METTL3_WT_vs_EV_F07.18037.18037.2 0.000175 18-Nov K.VEDAMLMFDK.T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|A0A6Q8PHP1|A0A6Q8PHP1_HUMAN" 6 1197.541 5.42 59567 18037 2 1197.541231 599.7778 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.03 3498.2 - 1.05E+06 - - - 0.2079 - 2.178 0.527 - 416.3 1 2 0 0.0002 10 0 0 0 4.83E+07 8.91E+06 - - - 5.1061 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18044.18044.2 0.0873 18-Oct R.FLLADNLYC[160.03]K.A sp|P61758|PFD3_HUMAN 1 1255.6271 3.49 59572 18044 2 1255.629215 628.8208 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 5.83 3499 - 4.03E+06 - - - 1.6884 - 2.037 0.338 - 281.9 1 2 0 0.0021 10 0 0 0 5.32E+07 1.52E+07 - - - 3.5228 1 230117_WJC_METTL3_WT_vs_EV_F07.18046.18046.2 3.58E-06 16-Oct K.NFDMVIVYK.D sp|Q9Y5B9|SP16H_HUMAN 1 1127.5685 1.04 59574 18046 2 1127.571628 564.7915 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.83 3499.3 - 1.39E+06 - - - 2.759 - 1.811 0.529 - 342.4 1 2 0 0.0031 9 0 0 0 1.23E+07 1.18E+07 - - - 4.6653 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18048.18048.2 0.0106 14-Sep R.LSVLLGLK.K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 841.5637 2.51 59576 18048 2 841.565511 421.7891 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3499.5 - 552122 - - - 2.1638 - 1.971 0.315 - 187.7 1 2 0 0.0018 8 0 0 0 5.28E+06 2.11E+06 - - - 3.4135 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18050.18050.2 9.28E-05 20-Oct R.C[160.03]LAPMMSEVIR.L "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 1305.6243 1.62 59578 18050 2 1305.625768 653.8194 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 5.99 3499.8 - 357765 - - - 1.0976 - 1.946 0.458 - 299.6 1 2 0 0.0014 11 0 0 0 3.49E+06 2.15E+06 - - - 4.2244 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.18054.18054.2 0.052 14-Aug R.LDTIFFAK.Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 953.5222 2.54 59580 18054 2 953.523254 477.7684 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3500.2 - 2.05E+06 - - - 1.0854 - 1.768 0.183 - 161.4 1 2 0 0.001 8 0 0 0 3.45E+08 1.36E+08 - - - 2.111 1 230117_WJC_METTL3_WT_vs_EV_F07.18055.18055.2 5.12E-08 18-Nov K.VDDAMLMFDK.T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1183.5253 1.39 59581 18055 2 1183.528274 592.7699 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 3.93 3500.3 - 2.03E+06 - - - 2.4858 - 2.337 0.598 - 524.2 1 2 0 0.0029 10 0 0 0 6.76E+07 4.86E+07 - - - 5.8264 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18058.18058.2 0.000516 18-Dec K.VDDAMLMFDK[136.11].T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1191.5395 1.39 59584 18058 2 1191.541149 596.777 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 3.93 3500.6 - 1.59E+06 - - - 1.3571 - 2.679 0.331 - 713.5 1 2 0 0.0016 10 0 0 0 6.76E+07 4.86E+07 - - - 4.2359 0.9613 230117_WJC_METTL3_WT_vs_EV_F07.18063.18063.2 2.84 18-May K.ILDATPAC[160.03]LP.- "sp|Q9Y5Y2|NUBP2_HUMAN,tr|B7Z6P0|B7Z6P0_HUMAN,tr|H3BQR2|H3BQR2_HUMAN" 3 1069.5478 - 59589 18063 2 1069.549553 535.7812 Cytosolic Fe-S cluster assembly factor NUBP2 OS=Homo sapiens OX=9606 GN=NUBP2 PE=1 SV=1 3.8 3501.1 - 757328 - - - 1.6558 - 0.876 0.142 - 49.1 2 2 0 0.0018 10 0 0 0 - - - - - -0.4148 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.18068.18068.2 0.0921 14-Jul R.LSVLLGLK[136.11].K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 849.5779 2.51 59594 18068 2 849.578658 425.7962 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3501.7 - 279759 - - - 0.904 - 1.459 0.27 - 72.7 1 2 0 0.0008 8 0 0 0 5.28E+06 2.11E+06 - - - 2.1743 1 230117_WJC_METTL3_WT_vs_EV_F07.18069.18069.2 1.45E-11 14/30 K.VLAQNSGFDLQETLVK.L sp|P40227|TCPZ_HUMAN 1 1760.9309 999 59595 18069 2 1760.937322 881.4727 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3501.8 - 263389 - - - 3.6668 - 3.152 0.681 - 545.8 1 2 0 0.0065 16 0 0 0 2.27E+06 0.00E+00 - - - 6.8913 0.9665 230117_WJC_METTL3_WT_vs_EV_F07.18071.18071.2 13.6 14-Jun R.TLIEELPS.- sp|Q9UHR6|ZNHI2_HUMAN 1 900.4804 - 59596 18071 2 900.478909 451.2475 Zinc finger HIT domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZNHIT2 PE=1 SV=1 3.79 3502.1 - 1.12E+06 - - - -1.6713 - 1.176 0.146 - 105 1 2 0 -0.0015 8 0 0 0 - - - - - 0.6078 0.9911 230117_WJC_METTL3_WT_vs_EV_F07.18072.18072.2 0.225 24-Nov R.LPLLPPESPGPLR.Q "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN,tr|A0A669KAX5|A0A669KAX5_HUMAN" 6 1384.8078 9.08 59597 18072 2 1384.816121 693.4112 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 6 3502.3 - 337911 - - - 5.9828 - 2.022 0.273 - 361.1 1 2 0 0.0083 13 0 0 0 2.66E+06 2.93E+05 - - - 2.8618 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18073.18073.2 0.00472 16-Sep R.AVALYFIDK[136.11].L "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN,tr|E5RIC7|E5RIC7_HUMAN" 4 1046.5892 0.001 59598 18073 2 1046.590363 524.3019 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 5.88 3502.3 - 5.10E+06 - - - 1.1275 - 1.883 0.394 - 286.2 1 2 0 0.0012 9 0 0 0 0.00E+00 5.19E+07 - - - 3.7816 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18074.18074.2 0.00242 16-Oct R.FLSPEFIPR.R "sp|P49406|RM19_HUMAN,tr|A0A0A0MRF4|A0A0A0MRF4_HUMAN" 2 1104.5968 0.97 59599 18074 2 1104.597982 553.3057 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 6 3502.4 - 3.97E+06 - - - 1.0873 - 1.648 0.42 - 307.3 1 2 0 0.0012 9 0 0 0 6.16E+07 6.35E+07 - - - 3.588 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.18075.18075.2 0.00132 16-Sep R.FLSPEFIPR[166.11].R "sp|P49406|RM19_HUMAN,tr|A0A0A0MRF4|A0A0A0MRF4_HUMAN" 2 1114.6051 0.97 59600 18075 2 1114.608118 558.3098 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 6 3502.4 - 3.85E+06 - - - 2.7516 - 1.806 0.338 - 251.3 1 2 0 0.0031 9 0 0 0 6.17E+07 6.37E+07 - - - 3.2466 1 230117_WJC_METTL3_WT_vs_EV_F07.18076.18076.2 0.000124 15/24 K.VLATTFDPYLGGR.N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1408.7351 12.27 59601 18076 2 1408.737865 705.3748 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3502.5 - 2.51E+06 - - - 1.9876 - 2.732 0.552 - 608.6 1 2 0 0.0028 13 0 0 0 9.64E+07 7.86E+06 - - - 5.6966 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.18077.18077.2 0.668 14-Aug R.GIFEPFGR.L "sp|Q14498|RBM39_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 5 921.4709 1.36 59602 18077 2 921.472056 461.7427 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 6 3502.5 - 1.88E+06 - - - 1.3066 - 1.59 0.131 - 212.2 1 2 0 0.0012 8 0 0 0 1.72E+08 1.27E+08 - - - 1.4068 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.18079.18079.2 0.203 14-Aug R.ADLIAYLK[136.11].K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 913.5364 1.28 59604 18079 2 913.53735 457.7755 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 5.88 3502.7 - 1.23E+06 - - - 1.0191 - 1.675 0.17 - 175.8 1 2 0 0.0009 8 0 0 0 3.71E+07 2.90E+07 - - - 1.852 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18084.18084.2 0.00404 18-Oct R.LITTQQWLIK[136.11].L sp|P00846|ATP6_HUMAN 1 1250.7478 1.18 59609 18084 2 1250.75008 626.3812 ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1 8.75 3503.3 - 613326 - - - 1.8157 - 2.079 0.437 - 267.9 1 2 0 0.0023 10 0 0 0 1.37E+07 1.16E+07 - - - 4.3109 1 230117_WJC_METTL3_WT_vs_EV_F07.18085.18085.2 0.000145 18-Nov R.LITTQQWLIK.L sp|P00846|ATP6_HUMAN 1 1242.7336 1.18 59610 18085 2 1242.734783 622.3741 ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1 8.75 3503.4 - 511457 - - - 0.9447 - 2.175 0.462 - 302 1 2 0 0.0012 10 0 0 0 1.37E+07 1.16E+07 - - - 4.6219 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18092.18092.2 0.000143 20-Aug R.AVVPSYIPLVK[136.11].K sp|P36551|HEM6_HUMAN 1 1192.7311 1.09 59616 18092 2 1192.733219 597.3728 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3504.2 - 4.45E+06 - - - 1.7799 - 1.742 0.36 - 220.1 1 2 0 0.0021 11 0 0 0 3.12E+08 2.87E+08 - - - 3.2008 0.9969 230117_WJC_METTL3_WT_vs_EV_F07.18093.18093.2 0.073 14-Jul R.ADLIAYLK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 905.5222 1.26 59617 18093 2 905.523723 453.7684 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 5.88 3504.3 - 3.72E+06 - - - 1.6609 - 1.399 0.177 - 119.1 1 2 0 0.0015 8 0 0 0 3.66E+07 2.90E+07 - - - 1.3605 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.18095.18095.2 0.0065 16-Nov K.IIGNLLYYR.Y "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1123.639 1.24 59619 18095 2 1123.642509 562.8268 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.59 3504.4 - 2.72E+06 - - - 3.1407 - 2.231 0.322 - 315.4 1 2 0 0.0035 9 0 0 0 6.26E+07 5.07E+07 - - - 3.7397 0.997 230117_WJC_METTL3_WT_vs_EV_F07.18096.18096.2 0.809 14-Aug K.ILILQGLK.Q "sp|Q9UNX4|WDR3_HUMAN,tr|D6RCT0|D6RCT0_HUMAN" 2 896.6059 1.03 59620 18096 2 896.606819 449.3102 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 8.75 3504.4 - 2.10E+06 - - - 1.0372 - 1.431 0.173 - 170.5 1 2 0 0.0009 8 0 0 0 2.90E+07 2.81E+07 - - - 1.3993 1 230117_WJC_METTL3_WT_vs_EV_F07.18098.18098.2 0.000878 22-Oct Y.TLVTYVPVTTFK.N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1367.7701 0.52 59622 18098 2 1367.774561 684.8923 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.26 3504.7 - 311715 - - - 3.2951 - 2.259 0.518 - 272.6 1 1 0 0.0045 12 0 0 0 1.40E+06 2.67E+06 - - - 5.0097 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18101.18101.2 7.49E-05 20-Sep R.AVVPSYIPLVK.K sp|P36551|HEM6_HUMAN 1 1184.7169 1.09 59623 18101 2 1184.719245 593.3657 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3505.1 - 7.48E+06 - - - 1.9828 - 1.847 0.424 - 272.3 1 2 0 0.0023 11 0 0 0 3.13E+08 2.87E+08 - - - 3.8318 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18102.18102.2 3.47E-06 20-Oct K.LTPVPDSFFAK.H sp|O94906|PRP6_HUMAN 1 1220.6441 0.07 59624 18102 2 1220.646991 611.3293 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.84 3505.1 - 1.47E+06 - - - 2.3479 - 1.908 0.493 - 267.5 1 2 0 0.0029 11 0 0 0 6.45E+07 8.89E+08 - - - 4.4291 1 230117_WJC_METTL3_WT_vs_EV_F07.18104.18104.2 4.43E-06 13/22 R.IGPLSPFTNAYR[166.11].R "sp|O75486|SUPT3_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 2 1344.7066 1.6 59626 18104 2 1344.709009 673.3606 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 8.75 3505.3 - 1.23E+06 - - - 1.8242 - 2.395 0.511 - 370.8 1 2 0 0.0025 12 0 0 0 3.94E+07 2.46E+07 - - - 5.1125 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18105.18105.2 0.000558 14/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 14.74 59627 18105 2 1484.912413 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3505.5 - 547252 - - - 3.0493 - 2.226 0.48 - 448.8 1 2 0 0.0045 15 0 0 0 5.01E+07 3.40E+06 - - - 4.5522 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.18106.18106.2 0.167 18-Aug K.VLALLDVPDK.S sp|Q9NX62|IMPA3_HUMAN 1 1081.6383 0.88 59628 18106 2 1081.640647 541.8264 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.21 3505.6 - 471682 - - - 2.1597 - 1.926 0.17 - 148.6 1 2 0 0.0023 10 0 0 0 6.34E+07 7.19E+07 - - - 2.1254 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.18111.18111.2 0.0257 14-Aug K.NILTEIYR.L sp|Q15907|RB11B_HUMAN 1 1020.5604 1.32 59632 18111 2 1020.562317 511.2875 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 6 3506.2 - 1.27E+06 - - - 1.8833 - 1.493 0.233 - 196 1 2 0 0.0019 8 0 0 0 4.59E+07 3.47E+07 - - - 1.9701 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18112.18112.2 0.0011 13/18 R.IC[160.03]DDELILIK.N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1230.653 9.42 59633 18112 2 1230.655877 616.3338 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3506.2 - 4.14E+06 - - - 2.3573 - 2.422 0.352 - 403.6 1 2 0 0.0029 10 0 0 0 1.14E+09 1.21E+08 - - - 4.1091 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.18113.18113.2 0.00022 20-Sep R.LLALNSLYSPK.L sp|P78527|PRKDC_HUMAN 1 1217.702 1.2 59634 18113 2 1217.70797 609.8583 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.59 3506.3 - 1.86E+06 - - - 4.924 - 2.138 0.315 - 226.7 1 2 0 0.006 11 0 0 0 7.64E+07 6.37E+07 - - - 3.4213 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.18121.18121.2 0.000156 18-Sep K.VLALLDVPDK[136.11].S sp|Q9NX62|IMPA3_HUMAN 1 1089.6525 0.89 59640 18121 2 1089.653924 545.8335 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.21 3507.1 - 1.57E+06 - - - 1.2967 - 1.869 0.257 - 212 1 2 0 0.0014 10 0 0 0 6.37E+07 7.19E+07 - - - 2.6845 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18122.18122.2 0.103 18-Nov K.EVLLVALGSR.Q sp|Q10570|CPSF1_HUMAN 1 1055.6339 1.63 59641 18122 2 1055.635463 528.8242 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6.1 3507.1 - 1.32E+06 - - - 1.4854 - 2.36 0.293 - 413.2 1 2 0 0.0016 10 0 0 0 2.78E+07 1.70E+07 - - - 3.6014 1 230117_WJC_METTL3_WT_vs_EV_F07.18123.18123.2 2.68E-06 14/18 R.IC[160.03]DDELILIK[136.11].N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1238.6672 9.4 59642 18123 2 1238.67036 620.3409 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3507.2 - 1.10E+06 - - - 2.5705 - 2.856 0.401 - 483.1 1 2 0 0.0032 10 0 0 0 1.13E+09 1.21E+08 - - - 4.931 1 230117_WJC_METTL3_WT_vs_EV_F07.18124.18124.3 1.07E-09 16/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 6.86 59643 18124 3 2187.045259 730.0199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3507.4 - 718729 - - - 3.3804 - 3.169 0.636 - 137.4 1 2 0 0.0074 20 0 0 0 1.28E+07 1.86E+06 - - - 8.4269 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.18129.18129.2 0.00024 20-Oct R.LLALNSLYSPK[136.11].L sp|P78527|PRKDC_HUMAN 1 1225.7162 1.2 59646 18129 2 1225.721499 613.8654 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.59 3508 - 3.50E+06 - - - 4.3444 - 2.251 0.423 - 260.1 1 2 0 0.0053 11 0 0 0 7.64E+07 6.37E+07 - - - 4.3586 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.18138.18138.2 0.00897 14-Aug R.LFGALLER[166.11].G sp|Q9BVI4|NOC4L_HUMAN 1 927.5417 1.31 59653 18138 2 927.544432 464.7781 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3509.1 - 8.76E+06 - - - 2.9217 - 1.911 0.244 - 213.9 1 2 0 0.0027 8 0 0 0 1.74E+08 1.33E+08 - - - 2.7955 0.9412 230117_WJC_METTL3_WT_vs_EV_F07.18140.18140.2 0.00678 18-Sep G.AGALQVVGLK[136.11].T sp|Q9P1Q0|VPS54_HUMAN 1 962.6004 2 59655 18140 2 962.602479 482.3075 Vacuolar protein sorting-associated protein 54 OS=Homo sapiens OX=9606 GN=VPS54 PE=1 SV=2 8.8 3509.2 - 7.33E+06 - - - 2.1432 - 1.71 0.311 - 168.3 1 1 0 0.0021 10 0 0 0 3.78E+08 1.89E+08 - - - 2.8349 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.18141.18141.2 0.0517 16-Aug R.SSIAGLLLK.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 900.5644 2.86 59656 18141 2 900.566535 451.2895 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.47 3509.2 - 2.19E+06 - - - 2.3507 - 1.749 0.283 - 150.6 1 2 0 0.0021 9 0 0 0 4.34E+07 1.51E+07 - - - 2.7479 1 230117_WJC_METTL3_WT_vs_EV_F07.18142.18142.2 2.76E-05 18-Sep R.VVYIFGPPVK.E sp|P49915|GUAA_HUMAN 1 1117.6536 2.97 59657 18142 2 1117.656972 559.8341 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 8.56 3509.3 - 1.57E+06 - - - 3.0457 - 2.103 0.494 - 350.9 1 2 0 0.0034 10 0 0 0 4.21E+07 1.42E+07 - - - 4.7636 0.8871 230117_WJC_METTL3_WT_vs_EV_F07.18152.18152.2 0.0576 18-Jul G.AGALQVVGLK.T sp|Q9P1Q0|VPS54_HUMAN 1 954.5862 2 59665 18152 2 954.587646 478.3004 Vacuolar protein sorting-associated protein 54 OS=Homo sapiens OX=9606 GN=VPS54 PE=1 SV=2 8.8 3510.6 - 2.03E+07 - - - 1.498 - 1.533 0.229 - 120.4 1 1 0 0.0014 10 0 0 0 3.78E+08 1.89E+08 - - - 1.9245 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.18153.18153.2 0.0123 14-Jul R.LFGALLER.G sp|Q9BVI4|NOC4L_HUMAN 1 917.5335 1.09 59666 18153 2 917.535411 459.774 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3510.6 - 1.05E+07 - - - 2.1351 - 1.768 0.251 - 153.8 1 2 0 0.002 8 0 0 0 1.27E+08 1.16E+08 - - - 2.6129 0.9738 230117_WJC_METTL3_WT_vs_EV_F07.18156.18156.2 1.63 14-Jun K.IDHILDAL.- "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 908.4967 - 59669 18156 2 908.498958 455.2556 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.2 3510.8 - 1.76E+06 - - - 2.4491 - 1.169 0.068 - 86.9 1 2 0 0.0022 8 0 0 0 - - - - - 0.0135 0.9771 230117_WJC_METTL3_WT_vs_EV_F07.18162.18162.2 3.6 14-Aug K.NLEIELLK.L "sp|Q9NVX0|HAUS2_HUMAN,tr|H3BP24|H3BP24_HUMAN,tr|J3QT48|J3QT48_HUMAN,tr|H3BQU2|H3BQU2_HUMAN,tr|H3BP16|H3BP16_HUMAN" 5 970.5699 3.78 59675 18162 2 970.570739 486.2922 HAUS augmin-like complex subunit 2 OS=Homo sapiens OX=9606 GN=HAUS2 PE=1 SV=1 4.53 3511.4 - 481595 - - - 0.8665 - 1.046 0.104 - 143.8 1 2 0 0.0008 8 0 0 0 7.89E+06 2.09E+06 - - - -0.0555 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18168.18168.2 0.00113 20-Nov K.VLTPELYAELR.A "sp|P12277|KCRB_HUMAN,tr|G3V461|G3V461_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 3 1302.7184 0.81 59679 18168 2 1302.720791 652.3665 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.53 3512.1 - 4.37E+06 - - - 1.8715 - 2.268 0.432 - 604.8 1 2 0 0.0024 11 0 0 0 5.91E+07 7.32E+07 - - - 4.4463 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.18170.18170.2 0.166 16-Sep R.VILLENLTR.F "sp|Q14999|CUL7_HUMAN,tr|A0A669KB95|A0A669KB95_HUMAN,tr|A0A669KAU7|A0A669KAU7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 4 1069.6495 1.58 59681 18170 2 1069.652461 535.832 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 5.97 3512.3 - 1.24E+06 - - - 2.7261 - 1.767 0.319 - 210.7 1 2 0 0.0029 9 0 0 0 1.87E+07 1.18E+07 - - - 3.0432 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.18172.18172.2 0.603 12-Jul K.FLELLPK.D "sp|P63010|AP2B1_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 5 858.5215 1.68 59683 18172 2 858.522885 430.268 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 6 3512.5 - 870989 - - - 1.6237 - 1.445 0.169 - 155.5 1 2 0 0.0014 7 0 0 0 4.42E+07 2.64E+07 - - - 1.4552 0.9825 230117_WJC_METTL3_WT_vs_EV_F07.18173.18173.2 0.175 20-Sep K.FVSFPTQVLAK[136.11].A sp|Q8TB61|S35B2_HUMAN 1 1243.7056 0.07 59684 18173 2 1243.704017 622.8601 Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Homo sapiens OX=9606 GN=SLC35B2 PE=1 SV=1 8.75 3512.6 - 1.08E+06 - - - -1.2808 - 1.238 0.175 - 178.8 1 2 0 -0.0016 11 0 0 0 6.50E+05 9.64E+06 - - - 0.9106 0.9938 230117_WJC_METTL3_WT_vs_EV_F07.18174.18174.2 17.6 12-Sep R.LLDFLQK.R "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 875.5117 1.32 59685 18174 2 875.510904 438.7631 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.84 3512.7 - 315094 - - - -0.8566 - 1.587 0.137 - 159.9 1 2 0 -0.0008 7 0 0 0 1.10E+08 8.34E+07 - - - 1.516 0.9927 230117_WJC_METTL3_WT_vs_EV_F07.18180.18180.2 0.169 14-Aug R.DVDFELIK.V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 977.507 3.54 59689 18180 2 977.509122 489.7608 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3513.3 - 2.66E+06 - - - 2.2087 - 1.31 0.132 - 174.6 1 2 0 0.0022 8 0 0 0 1.47E+09 4.14E+08 - - - 0.8297 0.8896 230117_WJC_METTL3_WT_vs_EV_F07.18181.18181.2 0.0155 16-Jul K.TVTAMDVVY.A sp|P62805|H4_HUMAN 1 997.479 - 59690 18181 2 997.481063 499.7468 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 3.8 3513.4 - 2.42E+06 - - - 2.0341 - 1.259 0.318 - 112.5 1 1 0 0.002 9 0 0 0 - - - - - 2.0554 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18183.18183.2 0.00404 22-Nov R.IGPLSPFTNAYR.R "sp|O75486|SUPT3_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 2 1334.6983 1.6 59692 18183 2 1334.700569 668.3564 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 8.75 3513.6 - 1.01E+06 - - - 1.7105 - 2.18 0.385 - 305.6 1 2 0 0.0023 12 0 0 0 3.94E+07 2.46E+07 - - - 3.9344 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.18184.18184.2 0.0167 18-Aug R.VVYIFGPPVK[136.11].E sp|P49915|GUAA_HUMAN 1 1125.6678 3.41 59693 18184 2 1125.670474 563.8412 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 8.56 3513.7 - 987859 - - - 2.4039 - 1.771 0.343 - 180.2 1 2 0 0.0027 10 0 0 0 3.70E+07 1.09E+07 - - - 3.1689 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.18185.18185.2 0.00874 14-Jul R.QMFLATWK.D sp|Q10567|AP1B1_HUMAN 1 1023.5212 0.39 59694 18185 2 1023.524188 512.7679 AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2 8.75 3513.8 - 900245 - - - 2.9457 - 1.434 0.279 - 131.9 1 2 0 0.003 8 0 0 0 8.79E+06 2.23E+07 - - - 2.1879 1 230117_WJC_METTL3_WT_vs_EV_F07.18187.18187.2 2.21E-06 20-Oct R.FPC[160.03]VVYINEVR.V sp|Q69YN4|VIR_HUMAN 1 1394.7017 2.61 59696 18187 2 1394.706238 698.3581 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 5.99 3514.1 - 298669 - - - 3.2846 - 2.092 0.537 - 422.6 1 2 0 0.0046 11 0 0 0 5.35E+06 2.05E+06 - - - 5.0026 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18192.18192.2 0.000218 18-Oct K.LYALGLVPTR[166.11].G sp|Q9NV31|IMP3_HUMAN 1 1111.6629 1.83 59699 18192 2 1111.666333 556.8387 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 8.75 3514.7 - 2.52E+06 - - - 3.0882 - 2.282 0.418 - 438.4 1 2 0 0.0034 10 0 0 0 7.60E+07 4.16E+07 - - - 4.4302 0.925 230117_WJC_METTL3_WT_vs_EV_F07.18193.18193.2 1.01 12-Apr K.FLELLPK[136.11].D "sp|P63010|AP2B1_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 5 866.5357 1.66 59700 18193 2 866.537242 434.2751 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 6 3514.8 - 946820 - - - 1.7899 - 0.873 0.164 - 29.1 29 2 0 0.0016 7 0 0 0 4.36E+07 2.62E+07 - - - -0.8318 1 230117_WJC_METTL3_WT_vs_EV_F07.18197.18197.2 1.17E-05 22-Dec K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 999 59704 18197 2 1474.744528 738.3781 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3515.2 - 390229 - - - 1.9807 - 2.428 0.548 - 572.4 1 2 0 0.0029 12 0 0 0 5.22E+06 0.00E+00 - - - 5.4216 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.18203.18203.2 0.039 14-Jul R.DVDFELIK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 985.5212 5.4 59708 18203 2 985.523098 493.7679 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3516 - 5.10E+06 - - - 1.9634 - 1.187 0.269 - 117.4 1 2 0 0.0019 8 0 0 0 1.40E+09 2.59E+08 - - - 1.5442 0.9881 230117_WJC_METTL3_WT_vs_EV_F07.18204.18204.2 0.261 12-Aug R.LLDFLQK[136.11].R "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 883.5259 1.32 59709 18204 2 883.527676 442.7702 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.84 3516.1 - 3.51E+06 - - - 2.0622 - 1.355 0.059 - 156.3 1 2 0 0.0018 7 0 0 0 1.10E+08 8.33E+07 - - - 0.4388 1 230117_WJC_METTL3_WT_vs_EV_F07.18206.18206.2 9.43E-07 13/22 K.LFVTNDAATILR[166.11].E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1342.7484 8.09 59711 18206 2 1342.751232 672.3815 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3516.2 - 2.50E+06 - - - 2.0935 - 2.635 0.503 - 550.5 1 2 0 0.0028 12 0 0 0 5.86E+09 7.25E+08 - - - 5.3046 0.9415 230117_WJC_METTL3_WT_vs_EV_F07.18207.18207.2 2.6 14-Jun R.LYPVLLVK.Q "sp|Q7Z7F7|RM55_HUMAN,tr|X6RIW1|X6RIW1_HUMAN" 2 943.6106 1.16 59712 18207 2 943.612542 472.8126 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 8.59 3516.2 - 1.92E+06 - - - 2.0157 - 1.019 0.037 - 80.7 1 2 0 0.0019 8 0 0 0 4.69E+07 4.04E+07 - - - -0.6295 0.9888 230117_WJC_METTL3_WT_vs_EV_F07.18208.18208.2 0.739 16-Aug R.VVLPYLVPK[136.11].L sp|Q92616|GCN1_HUMAN 1 1034.662 1.22 59713 18208 2 1034.66412 518.3383 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.56 3516.3 - 1.59E+06 - - - 2.0934 - 1.298 0.094 - 208.1 1 2 0 0.0022 9 0 0 0 6.77E+07 5.57E+07 - - - 0.4892 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.18209.18209.2 0.0365 16-Aug R.VVLPYLVPK.L sp|Q92616|GCN1_HUMAN 1 1026.6478 1.17 59714 18209 2 1026.651153 514.3312 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.56 3516.4 - 1.42E+06 - - - 3.3108 - 1.347 0.281 - 229.7 1 2 0 0.0034 9 0 0 0 6.53E+07 5.57E+07 - - - 1.9772 0.9773 230117_WJC_METTL3_WT_vs_EV_F07.18210.18210.2 0.564 20-Jun K.YGLLPSHASYL.- sp|Q86U90|YRDC_HUMAN 1 1219.6237 - 59715 18210 2 1219.627281 610.8191 "YrdC domain-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=YRDC PE=1 SV=1" 6.74 3516.4 - 1.28E+06 - - - 2.9165 - 1.04 0.154 - 50.1 1 2 0 0.0036 11 0 0 0 - - - - - 0.2834 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.18213.18213.2 0.00127 20-Nov K.AVFVLGDAELK.G "sp|Q93074|MED12_HUMAN,tr|Q7Z3Z5|Q7Z3Z5_HUMAN" 2 1160.6441 0.15 59718 18213 2 1160.649996 581.3293 Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens OX=9606 GN=MED12 PE=1 SV=4 4.37 3516.7 - 377259 - - - 5.0584 - 2.238 0.379 - 343.4 1 2 0 0.0059 11 0 0 0 4.72E+06 3.22E+07 - - - 4.0177 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18217.18217.2 0.0127 14-Sep K.LDYILGLK[136.11].L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 941.5677 0.78 59720 18217 2 941.569634 471.7911 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3517.3 - 3.87E+06 - - - 2.0338 - 1.915 0.308 - 260.2 1 2 0 0.0019 8 0 0 0 5.45E+08 6.98E+08 - - - 3.2748 0.9309 230117_WJC_METTL3_WT_vs_EV_F07.18218.18218.2 1.6 16-Sep R.TLADIIMEK.L "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1032.5525 0.64 59721 18218 2 1032.551298 517.2835 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.37 3517.3 - 1.79E+06 - - - -1.1961 - 1.303 0.03 - 210 2 2 0 -0.0012 9 0 0 0 3.83E+07 6.02E+07 - - - -0.1066 0.9926 230117_WJC_METTL3_WT_vs_EV_F07.18224.18224.2 0.00856 18-Aug K.ANPDLPILIR[166.11].E sp|O43678|NDUA2_HUMAN 1 1130.6687 2.53 59727 18224 2 1130.675654 566.3416 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3 5.88 3518 - 270877 - - - 6.138 - 1.557 0.404 - 158.2 1 2 0 0.0069 10 0 0 0 1.80E+07 7.10E+06 - - - 3.2586 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18229.18229.2 0.01 14-Sep K.LDYILGLK.L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 933.5535 0.78 59730 18229 2 933.554825 467.784 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3518.5 - 6.30E+06 - - - 1.399 - 1.897 0.313 - 268.2 1 2 0 0.0013 8 0 0 0 5.45E+08 6.97E+08 - - - 3.2834 0.9709 230117_WJC_METTL3_WT_vs_EV_F07.18230.18230.2 0.00919 20-Nov R.SALLVQLATAR.P "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1141.6819 2.27 59731 18230 2 1141.684713 571.8482 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 9.47 3518.6 - 1.21E+06 - - - 2.4569 - 2.328 0.401 - 401 1 1 0 0.0028 11 0 0 0 4.72E+07 2.08E+07 - - - 4.2879 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18231.18231.2 0.0311 16-Sep K.LFLVQLQEK[136.11].A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1124.6685 1.52 59732 18231 2 1124.671263 563.3415 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3518.6 - 1.13E+06 - - - 2.4603 - 1.842 0.336 - 205.6 1 2 0 0.0028 9 0 0 0 5.69E+07 3.75E+07 - - - 3.2891 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.18232.18232.2 3.07 14-Aug R.LLILMEAR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 967.5764 1.42 59733 18232 2 967.578217 484.7955 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6 3518.7 - 1.13E+06 - - - 1.8851 - 1.789 0.251 - 211.9 1 2 0 0.0018 8 0 0 0 4.14E+07 2.91E+07 - - - 2.6486 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18239.18239.2 0.0874 16-Aug K.LFLVQLQEK.A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1116.6543 1.14 59738 18239 2 1116.65622 559.3344 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3519.6 - 1.33E+06 - - - 1.723 - 1.726 0.357 - 196 1 2 0 0.0019 9 0 0 0 3.57E+07 3.14E+07 - - - 3.2562 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.18242.18242.2 0.000332 18-Aug K.IVLLMAYSGK.G "sp|Q9Y606|TRUA_HUMAN,tr|G8JLB3|G8JLB3_HUMAN,tr|F8W9U5|F8W9U5_HUMAN,tr|F5H168|F5H168_HUMAN,tr|F5H1B2|F5H1B2_HUMAN,tr|F5GY32|F5GY32_HUMAN,tr|F5GXL3|F5GXL3_HUMAN" 7 1093.6206 2.41 59741 18242 2 1093.61946 547.8176 tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3 8.59 3519.9 - 923832 - - - -0.9994 - 1.585 0.393 - 104.8 1 2 0 -0.0011 10 0 0 0 2.38E+07 9.84E+06 - - - 3.229 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.18246.18246.2 0.0997 18-Oct K.LAVNMVPFPR[166.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1152.6353 3.12 59743 18246 2 1152.637282 577.3249 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3520.4 - 1.69E+06 - - - 1.7152 - 1.766 0.3 - 243.6 1 2 0 0.002 10 0 0 0 1.02E+09 3.28E+08 - - - 2.8436 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.18248.18248.2 1.19 14-Aug R.LLILMEAR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 957.5681 1.43 59745 18248 2 957.568117 479.7913 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6 3520.6 - 1.82E+06 - - - -0.0063 - 1.744 0.156 - 192.8 1 2 0 0 8 0 0 0 4.13E+07 2.89E+07 - - - 1.8706 1 230117_WJC_METTL3_WT_vs_EV_F07.18250.18250.2 9.02E-06 13/20 R.IVLLDSSLEYK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1278.7071 98.89 59747 18250 2 1278.710706 640.3608 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3520.8 - 768511 - - - 2.8052 - 2.677 0.487 - 553.3 1 2 0 0.0036 11 0 0 0 2.83E+07 2.86E+05 - - - 5.3007 0.9884 230117_WJC_METTL3_WT_vs_EV_F07.18251.18251.2 0.00735 20-Sep K.VITC[160.03]GWDGLIK.L sp|O60508|PRP17_HUMAN 1 1260.6536 5.6 59748 18251 2 1260.650697 631.3341 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.8 3520.9 - 478576 - - - -2.3377 - 1.475 0.231 - 240.5 1 2 0 -0.0029 11 0 0 0 7.89E+06 1.41E+06 - - - 1.7977 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.18258.18258.3 0.00136 Dec-44 K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 8.8 59753 18258 3 1332.743016 445.254 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3521.7 - 7.19E+06 - - - 2.1497 - 2.01 0.205 - 162 1 2 0 0.0029 12 0 0 0 1.61E+08 1.83E+07 - - - 2.7599 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.18259.18259.2 0.0904 16-Oct R.NFFGPEFVK.M sp|Q12923|PTN13_HUMAN 1 1083.5389 0.15 59754 18259 2 1083.541243 542.7767 Tyrosine-protein phosphatase non-receptor type 13 OS=Homo sapiens OX=9606 GN=PTPN13 PE=1 SV=2 6 3521.8 - 718347 - - - 2.1328 - 1.303 0.289 - 237.8 1 2 0 0.0023 9 0 0 0 1.80E+07 1.17E+08 - - - 1.9405 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18263.18263.2 0.00531 18-Oct K.YLAIAPPIIK.Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1097.6849 1.86 59756 18263 2 1097.685666 549.8497 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3522.3 - 2.69E+06 - - - 0.727 - 1.645 0.364 - 348.3 1 2 0 0.0008 10 0 0 0 2.26E+08 1.21E+08 - - - 3.1186 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18265.18265.2 0.0287 16-Jul K.VLEALQVLR[166.11].C "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1049.6472 1.35 59758 18265 2 1049.647196 525.8309 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.97 3522.5 - 2.23E+06 - - - -0.0514 - 2.027 0.331 - 160.8 1 2 0 -0.0001 9 0 0 0 6.33E+07 4.68E+07 - - - 3.5299 0.8525 230117_WJC_METTL3_WT_vs_EV_F07.18270.18270.2 0.332 12-Jun H.ILLWDTR.N "sp|Q9BTV6|DPH7_HUMAN,sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 3 915.5178 0.43 59761 18270 2 915.518215 458.7662 Diphthine methyltransferase OS=Homo sapiens OX=9606 GN=DPH7 PE=1 SV=2 5.84 3523.1 - 3.65E+07 - - - 0.4511 - 1.357 0.243 - 157 1 1 0 0.0004 7 0 0 0 1.01E+09 2.32E+09 - - - 1.803 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18271.18271.2 0.000388 14-Sep R.VVDLLVIK.G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 897.5899 2.07 59762 18271 2 897.590208 449.8022 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3523.1 - 6.58E+06 - - - 0.3376 - 1.7 0.492 - 237.7 1 2 0 0.0003 8 0 0 0 1.78E+08 8.62E+07 - - - 4.2752 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18272.18272.2 0.000698 16-Sep K.LLQDFFNGK.E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1080.5604 9.21 59763 18272 2 1080.561245 541.2875 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3523.2 - 886837 - - - 0.7866 - 1.845 0.425 - 213.6 1 2 0 0.0008 9 0 0 0 1.24E+08 1.35E+07 - - - 3.9517 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18276.18276.2 0.00988 16-Oct K.VLEALQVLR.C "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1039.639 1.35 59765 18276 2 1039.640163 520.8268 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.97 3523.8 - 3.33E+06 - - - 1.1379 - 1.988 0.428 - 329.3 1 2 0 0.0012 9 0 0 0 6.33E+07 4.68E+07 - - - 4.1897 0.9823 230117_WJC_METTL3_WT_vs_EV_F07.18277.18277.2 3.51 12-Jul R.ALLFIPR.R "sp|P08238|HS90B_HUMAN,sp|O00585|CCL21_HUMAN,tr|Q5VZ73|Q5VZ73_HUMAN" 3 828.5222 2.01 59766 18277 2 828.522097 415.2684 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 9.79 3523.8 - 1.28E+06 - - - -0.0748 - 1.325 0.059 - 169.2 1 2 0 -0.0001 7 0 0 0 7.08E+08 3.52E+08 - - - 0.3684 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.18278.18278.2 0.21 12-Jun R.AVFWDIK.N sp|Q6P2Q9|PRP8_HUMAN 1 877.4698 1.16 59767 18278 2 877.470268 439.7422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3523.9 - 2.76E+06 - - - 0.5447 - 1.284 0.262 - 129.9 1 2 0 0.0005 7 0 0 0 1.43E+08 1.23E+08 - - - 1.7681 1 230117_WJC_METTL3_WT_vs_EV_F07.18280.18280.2 6.08E-08 17/30 R.IINEPTAAAIAYGLDK.R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1658.8879 40.7 59769 18280 2 1658.888603 830.4512 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3524.1 - 562003 - - - 0.4015 - 2.563 0.537 - 473.1 1 2 0 0.0007 16 0 0 0 3.01E+07 7.39E+05 - - - 5.321 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18284.18284.2 0.000608 14-Nov R.VVDLLVIK[136.11].G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 905.6041 2.07 59771 18284 2 905.604382 453.8093 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3524.6 - 4.36E+06 - - - 0.3059 - 1.922 0.476 - 352.5 1 2 0 0.0003 8 0 0 0 1.78E+08 8.62E+07 - - - 4.5272 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18296.18296.2 0.000576 14-Aug R.YQDILVFR.S "sp|P19623|SPEE_HUMAN,tr|K7EKM4|K7EKM4_HUMAN" 2 1052.5655 6.96 59781 18296 2 1052.566628 527.29 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.84 3525.9 - 6.64E+06 - - - 1.0897 - 1.874 0.476 - 204.3 1 2 0 0.0011 8 0 0 0 1.77E+08 2.55E+07 - - - 4.4506 0.9788 230117_WJC_METTL3_WT_vs_EV_F07.18299.18299.2 0.0198 16-Jul K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 20.42 59784 18299 2 1014.539724 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3526.2 - 695469 - - - 5.0752 - 1.727 0.123 - 94.7 2 2 0 0.0052 9 0 0 0 2.97E+07 1.46E+06 - - - 1.3941 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.18300.18300.2 0.0246 18-Jun K.FYALDPSFPR[166.11].M sp|Q08J23|NSUN2_HUMAN 1 1221.6058 1.66 59785 18300 2 1221.60614 611.8102 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3526.3 - 481154 - - - 0.2955 - 1.282 0.331 - 97.7 1 2 0 0.0004 10 0 0 0 3.66E+07 2.21E+07 - - - 2.1791 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.18301.18301.3 0.104 Aug-36 K.LAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1142.627 3.23 59786 18301 3 1142.627797 381.883 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3526.4 - 352525 - - - 0.6669 - 1.561 0.214 - 110.2 1 2 0 0.0008 10 0 0 0 8.35E+06 2.59E+06 - - - 2.2262 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18305.18305.2 0.000455 18-Aug K.YLAIAPPIIK[136.11].Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1105.6991 1.86 59788 18305 2 1105.699232 553.8568 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3527 - 3.69E+06 - - - 0.1483 - 1.612 0.405 - 200.5 1 2 0 0.0002 10 0 0 0 2.26E+08 1.21E+08 - - - 3.3651 0.9753 230117_WJC_METTL3_WT_vs_EV_F07.18309.18309.2 0.701 12-Jul K.IVIPILK[136.11].Y "sp|Q8NCM8|DYHC2_HUMAN,sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|A0A3B3ISP9|A0A3B3ISP9_HUMAN,tr|F6XAQ5|F6XAQ5_HUMAN" 6 802.5772 1.43 59792 18309 2 802.576732 402.2959 Cytoplasmic dynein 2 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC2H1 PE=1 SV=4 8.75 3527.5 - 249827 - - - -0.5358 - 1.295 0.063 - 137.2 1 2 0 -0.0004 7 0 0 0 1.02E+07 7.10E+06 - - - 0.3253 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18313.18313.2 0.00863 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 4036.09 59795 18313 2 1006.570794 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3528 - 1.24E+07 - - - 0.8902 - 1.705 0.452 - 249.8 1 2 0 0.0009 9 0 0 0 1.23E+09 3.05E+05 - - - 3.9228 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18315.18315.2 0.0146 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 4036.09 59796 18315 2 1006.570947 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3528.2 - 2.00E+07 - - - 1.0422 - 1.929 0.478 - 253.1 1 2 0 0.001 9 0 0 0 1.23E+09 3.05E+05 - - - 4.4719 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18316.18316.2 0.00196 18-Oct R.VLITTDLLAR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 1123.684 1.48 59797 18316 2 1123.685733 562.8493 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3528.2 - 2.89E+06 - - - 1.5156 - 1.985 0.433 - 282.9 1 2 0 0.0017 10 0 0 0 2.28E+08 1.54E+08 - - - 4.1524 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.18317.18317.2 0.0981 12-Jul R.LVVLPFR[166.11].R sp|Q10570|CPSF1_HUMAN 1 852.5461 1.71 59798 18317 2 852.546969 427.2803 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 9.75 3528.4 - 1.27E+06 - - - 1.0439 - 1.435 0.195 - 170.8 1 2 0 0.0009 7 0 0 0 4.68E+07 2.74E+07 - - - 1.6254 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.18319.18319.2 0.000371 18-Sep K.FYALDPSFPR.M sp|Q08J23|NSUN2_HUMAN 1 1211.5975 1.67 59800 18319 2 1211.600935 606.806 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3528.6 - 1.11E+06 - - - 2.8277 - 1.468 0.461 - 167.1 1 2 0 0.0034 10 0 0 0 3.69E+07 2.21E+07 - - - 3.5165 0.9957 230117_WJC_METTL3_WT_vs_EV_F07.18322.18322.2 0.2 14-Aug R.LTFLNSFK.M "sp|Q9Y487|VPP2_HUMAN,sp|Q93050|VPP1_HUMAN,tr|F5H1T6|F5H1T6_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 5 968.5331 2.46 59803 18322 2 968.536182 485.2738 V-type proton ATPase 116 kDa subunit a2 OS=Homo sapiens OX=9606 GN=ATP6V0A2 PE=1 SV=2 8.75 3529 - 358687 - - - 3.1635 - 1.503 0.188 - 116.6 1 2 0 0.0031 8 0 0 0 5.62E+06 2.29E+06 - - - 1.6575 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18324.18324.2 0.00468 18-Aug K.LAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1142.627 3.12 59804 18324 2 1142.62898 572.3208 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3529.2 - 7.01E+07 - - - 1.7022 - 1.687 0.369 - 278 1 2 0 0.0019 10 0 0 0 1.02E+09 3.28E+08 - - - 3.2255 0.9673 230117_WJC_METTL3_WT_vs_EV_F07.18331.18331.2 0.0124 16-Sep R.LIDFLEC[160.03]GK[136.11].T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1101.562 0.96 59809 18331 2 1101.556055 551.7883 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3530 - 1.59E+07 - - - -5.3805 - 1.467 0.338 - 192.7 1 2 0 -0.0059 9 0 0 0 1.93E+08 2.02E+08 - - - 2.6443 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18332.18332.2 8.60E-05 16-Sep R.LIDFLEC[160.03]GK.T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1093.5478 0.96 59810 18332 2 1093.549111 547.7812 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3530 - 1.56E+07 - - - 1.2153 - 1.795 0.47 - 202.1 1 2 0 0.0013 9 0 0 0 1.96E+08 2.05E+08 - - - 4.2045 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.18333.18333.2 0.0326 14-Jul R.VPTIFPLR[166.11].G sp|Q96EK4|THA11_HUMAN 1 951.5781 36.3 59811 18333 2 951.579809 476.7963 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 9.72 3530.1 - 1.02E+06 - - - 1.7876 - 1.47 0.331 - 139.8 1 2 0 0.0017 8 0 0 0 6.90E+08 1.90E+07 - - - 2.6472 0.9715 230117_WJC_METTL3_WT_vs_EV_F07.18335.18335.2 0.00029 20-Aug F.IFWAPESAPLK.S "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 1257.6758 3.87 59813 18335 2 1257.678121 629.8452 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6 3530.4 - 578186 - - - 1.8773 - 2.003 0.394 - 179.4 1 1 0 0.0024 11 0 0 0 1.42E+07 3.67E+06 - - - 3.8295 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18338.18338.2 1.77E-05 22-Sep K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 8.1 59815 18338 2 1332.741931 667.3774 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3530.7 - 3.78E+07 - - - 1.3356 - 1.869 0.475 - 271 1 2 0 0.0018 12 0 0 0 5.85E+09 7.23E+08 - - - 4.1943 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18351.18351.2 0.00481 14-Sep R.IGVMSLIR[166.11].K "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 897.5345 1.53 59825 18351 2 897.535567 449.7745 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 3532 - 2.96E+06 - - - 1.1565 - 1.735 0.359 - 256.2 1 2 0 0.001 8 0 0 0 3.96E+07 2.59E+07 - - - 3.3541 0.9205 230117_WJC_METTL3_WT_vs_EV_F07.18354.18354.2 0.0208 18-Oct N.MVVDAVLAIK.Y "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1057.6206 23.41 59828 18354 2 1057.621064 529.8176 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.59 3532.3 - 955403 - - - 0.4832 - 1.617 0.283 - 267.1 1 1 0 0.0005 10 0 0 0 1.02E+07 4.37E+05 - - - 2.4725 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.18356.18356.2 0.0108 14-Aug R.FLFPEGIK[136.11].G "sp|O75891|AL1L1_HUMAN,sp|Q3SY69|AL1L2_HUMAN,tr|C9IZ36|C9IZ36_HUMAN,tr|A0A494C1M4|A0A494C1M4_HUMAN" 4 957.5415 1.46 59830 18356 2 957.542787 479.778 Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L1 PE=1 SV=2 6 3532.6 - 533801 - - - 1.3399 - 1.389 0.328 - 152.9 1 2 0 0.0013 8 0 0 0 1.01E+07 6.91E+06 - - - 2.4542 1 230117_WJC_METTL3_WT_vs_EV_F07.18357.18357.2 5.63E-05 13/22 K.IPGIIIAASAVR[166.11].A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1189.7422 2.23 59831 18357 2 1189.752664 595.8784 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3532.7 - 356842 - - - 8.7843 - 2.511 0.499 - 505.5 1 2 0 0.0105 12 0 0 0 1.44E+07 6.45E+06 - - - 5.1458 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18362.18362.2 0.00259 14-Sep R.IGVMSLIR.K "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 887.5263 1.52 59833 18362 2 887.527394 444.7704 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 9.75 3533.4 - 2.04E+06 - - - 1.2788 - 1.833 0.35 - 265.3 1 2 0 0.0011 8 0 0 0 3.95E+07 2.59E+07 - - - 3.4533 0.9841 230117_WJC_METTL3_WT_vs_EV_F07.18364.18364.2 0.00965 22-Oct K.IPGIIIAASAVR.A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1179.7339 2.41 59835 18364 2 1179.744838 590.8742 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3533.6 - 648795 - - - 9.2351 - 2.309 0.408 - 314.6 1 2 0 0.0109 12 0 0 0 4.02E+07 1.66E+07 - - - 4.2529 0.9947 230117_WJC_METTL3_WT_vs_EV_F07.18366.18366.2 0.312 16-Nov K.TLGILGLGR[166.11].L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 908.5683 2.1 59837 18366 2 908.568896 455.2914 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3533.9 - 305806 - - - 0.6868 - 1.559 0.091 - 393.7 1 2 0 0.0006 9 0 0 0 2.61E+08 1.24E+08 - - - 0.9976 0.999 230117_WJC_METTL3_WT_vs_EV_F07.18371.18371.2 0.0597 20-Nov R.VVGVLLGSWQK[136.11].K "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 1192.7059 1.45 59840 18371 2 1192.707384 597.3602 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 8.72 3534.6 - 744581 - - - 1.2073 - 2.091 0.188 - 362.1 1 2 0 0.0014 11 0 0 0 1.83E+07 1.26E+07 - - - 2.4246 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18372.18372.2 0.00744 18-Dec R.ILELDQELIK[136.11].A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1220.7108 1.35 59841 18372 2 1220.712406 611.3627 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3534.6 - 871640 - - - 1.3525 - 2.276 0.212 - 370.1 1 2 0 0.0017 10 0 0 0 2.58E+07 1.91E+07 - - - 2.9019 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18373.18373.2 7.34E-05 20-Oct R.LGIPDAVSYIK.K sp|O94874|UFL1_HUMAN 1 1174.6598 1.03 59842 18373 2 1174.660297 588.3372 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.83 3534.7 - 398273 - - - 0.4444 - 2.096 0.319 - 167.3 1 2 0 0.0005 11 0 0 0 1.77E+07 1.72E+07 - - - 3.3989 1 230117_WJC_METTL3_WT_vs_EV_F07.18380.18380.2 0.00016 22-Nov R.FLAVGLVDNTVR[166.11].L sp|Q15393|SF3B3_HUMAN 1 1312.7379 1.12 59848 18380 2 1312.740283 657.3762 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3535.6 - 1.69E+06 - - - 1.8488 - 2.283 0.495 - 516.1 1 2 0 0.0024 12 0 0 0 9.15E+07 8.20E+07 - - - 4.8683 1 230117_WJC_METTL3_WT_vs_EV_F07.18381.18381.2 1.52E-05 13/20 R.VVGVLLGSWQK.K "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 1184.6917 1.38 59849 18381 2 1184.700357 593.3531 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 8.72 3535.7 - 825701 - - - 7.2702 - 2.265 0.519 - 576.8 1 2 0 0.0086 11 0 0 0 1.74E+07 1.26E+07 - - - 5.0834 0.9959 230117_WJC_METTL3_WT_vs_EV_F07.18382.18382.2 3.51 16-Dec K.TLGILGLGR.L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 898.56 2.1 59850 18382 2 898.56332 450.2873 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3535.7 - 1.15E+06 - - - 3.6926 - 1.936 0.146 - 451.5 1 2 0 0.0033 9 0 0 0 2.61E+08 1.24E+08 - - - 2.0295 1 230117_WJC_METTL3_WT_vs_EV_F07.18385.18385.2 1.88E-05 26-Dec K.VLIPSYAAGSIIGK.G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|F8W659|F8W659_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|F8VYI3|F8VYI3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|I3L2B5|I3L2B5_HUMAN" 8 1387.8075 2.63 59853 18385 2 1387.811443 694.911 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.56 3536 - 204482 - - - 2.8397 - 2.134 0.526 - 229 1 2 0 0.0039 14 0 0 0 5.90E+06 2.25E+06 - - - 4.827 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18389.18389.2 0.0265 16-Jul R.YYIDADLLR.E sp|Q7Z3B4|NUP54_HUMAN 1 1140.5815 3.35 59855 18389 2 1140.583604 571.298 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.21 3536.6 - 1.61E+07 - - - 1.8228 - 1.505 0.423 - 127.9 1 2 0 0.0021 9 0 0 0 4.47E+07 1.33E+07 - - - 3.3473 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18390.18390.2 0.0111 20-Nov K.LALDVEIATYR.K "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1262.6871 175.21 59856 18390 2 1262.689346 632.3508 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 3536.6 - 1.05E+07 - - - 1.816 - 2.49 0.325 - 573.6 1 2 0 0.0023 11 0 0 0 3.48E+07 1.99E+05 - - - 3.9087 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.18391.18391.2 0.098 18-Dec R.ILELDQELIK.A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1212.6966 1.35 59857 18391 2 1212.69907 607.3556 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3536.7 - 9.77E+06 - - - 2.0739 - 2.199 0.23 - 401.3 1 2 0 0.0025 10 0 0 0 2.58E+07 1.91E+07 - - - 2.9385 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.18392.18392.2 0.0121 16-Jul R.YYIDADLLR[166.11].E sp|Q7Z3B4|NUP54_HUMAN 1 1150.5898 3.42 59858 18392 2 1150.59292 576.3022 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.21 3536.7 - 6.78E+06 - - - 2.716 - 1.395 0.267 - 131.5 1 2 0 0.0031 9 0 0 0 4.45E+07 1.30E+07 - - - 1.9752 0.8968 230117_WJC_METTL3_WT_vs_EV_F07.18395.18395.2 0.0246 16-Aug R.EHALLAYTL.G "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 12 1029.5495 - 59861 18395 2 1029.55299 515.782 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.24 3536.9 - 2.71E+06 - - - 3.3937 - 1.612 0.341 - 168.2 1 1 0 0.0035 9 0 0 0 - - - - - 2.9399 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.18398.18398.2 0.105 16-Sep K.LAIYGMLPK[136.11].N "sp|Q9BYD1|RM13_HUMAN,tr|E5RJI7|E5RJI7_HUMAN" 2 1012.5871 22.92 59864 18398 2 1012.591013 507.3008 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 8.59 3537.2 - 1.70E+06 - - - 3.89 - 1.891 0.332 - 162.8 1 2 0 0.0039 9 0 0 0 5.39E+08 2.35E+07 - - - 3.3351 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18399.18399.2 0.134 20-Oct K.NLIDAGVDALR.V "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1155.6248 1 59865 18399 2 1155.62717 578.8197 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.21 3537.3 - 1.63E+06 - - - 2.0621 - 1.995 0.334 - 237.9 1 2 0 0.0024 11 0 0 0 3.12E+06 3.12E+06 - - - 3.3755 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.18400.18400.2 0.00689 20-Oct K.LDPGLIMEQVK[136.11].V sp|Q9Y5L4|TIM13_HUMAN 1 1249.6832 2.23 59866 18400 2 1249.686381 625.8489 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3537.4 - 1.37E+06 - - - 2.5775 - 1.963 0.318 - 424 1 2 0 0.0032 11 0 0 0 9.51E+06 4.28E+06 - - - 3.2133 0.9904 230117_WJC_METTL3_WT_vs_EV_F07.18401.18401.2 0.409 14-Jul K.LFNQINIS.- sp|Q92905|CSN5_HUMAN 1 947.5076 - 59867 18401 2 947.508863 474.7611 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 5.52 3537.5 - 1.27E+06 - - - 1.2992 - 1.132 0.147 - 77.6 1 2 0 0.0012 8 0 0 0 - - - - - 0.5003 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18402.18402.3 0.00126 Sep-44 R.FLAVGLVDNTVR.L sp|Q15393|SF3B3_HUMAN 1 1302.7296 8.5 59868 18402 3 1302.733727 435.2505 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3537.6 - 1.08E+06 - - - 3.1787 - 1.724 0.392 - 84.2 1 2 0 0.0041 12 0 0 0 7.29E+07 8.58E+06 - - - 4.4189 0.985 230117_WJC_METTL3_WT_vs_EV_F07.18403.18403.2 0.0379 14-Jul K.IPISLVLR[166.11].L "sp|O95747|OXSR1_HUMAN,tr|C9JIG9|C9JIG9_HUMAN" 2 919.6094 1.17 59869 18403 2 919.611132 460.812 Serine\threonine-protein kinase OSR1 OS=Homo sapiens OX=9606 GN=OXSR1 PE=1 SV=1 9.75 3537.8 - 1.04E+06 - - - 1.8747 - 1.327 0.047 - 107.9 1 2 0 0.0017 8 0 0 0 3.42E+06 2.92E+06 - - - 0.2409 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18404.18404.2 0.115 20-Oct K.NLIDAGVDALR[166.11].V "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1165.6331 1.17 59870 18404 2 1165.633569 583.8238 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.21 3537.9 - 974774 - - - 0.4392 - 1.984 0.38 - 244.3 1 2 0 0.0005 11 0 0 0 3.12E+06 2.68E+06 - - - 3.7009 0.9943 230117_WJC_METTL3_WT_vs_EV_F07.18408.18408.2 0.0927 13/22 R.AAMEALVVEVTK[136.11].Q sp|Q08211|DHX9_HUMAN 1 1267.6937 8.8 59874 18408 2 1267.697641 634.8541 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.53 3538.4 - 799154 - - - 3.0899 - 1.136 0.272 - 228.8 1 2 0 0.0039 12 0 0 0 1.45E+07 1.65E+06 - - - 1.3843 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18411.18411.2 0.000911 20-Nov K.LDPGLIMEQVK.V sp|Q9Y5L4|TIM13_HUMAN 1 1241.669 2.23 59876 18411 2 1241.672185 621.8418 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3538.7 - 556019 - - - 2.5973 - 2.008 0.41 - 403.6 1 2 0 0.0032 11 0 0 0 9.51E+06 4.28E+06 - - - 3.9542 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18415.18415.2 0.00332 22-Nov K.LIVDPALDPALR.R "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN,tr|C9J2Z9|C9J2Z9_HUMAN" 3 1291.75 2.66 59880 18415 2 1291.751092 646.8823 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.21 3538.9 - 766899 - - - 0.8554 - 1.965 0.366 - 368.3 1 2 0 0.0011 12 0 0 0 1.93E+07 7.26E+06 - - - 3.5213 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.18416.18416.2 6.73 12-Sep K.ILVDLLK.L "sp|Q6P582|MZT2A_HUMAN,sp|Q6NZ67|MZT2B_HUMAN,tr|H7C202|H7C202_HUMAN,tr|B8ZZ87|B8ZZ87_HUMAN,tr|A0A494C0V9|A0A494C0V9_HUMAN,tr|H7BZ50|H7BZ50_HUMAN,tr|H7C173|H7C173_HUMAN" 7 812.5371 2.65 59881 18416 2 812.538525 407.2758 Mitotic-spindle organizing protein 2A OS=Homo sapiens OX=9606 GN=MZT2A PE=1 SV=2 5.84 3539.1 - 484673 - - - 1.7033 - 2.099 0.196 - 214.4 1 2 0 0.0014 7 0 0 0 1.44E+07 5.43E+06 - - - 2.8376 0.9899 230117_WJC_METTL3_WT_vs_EV_F07.18423.18423.2 5.18E-05 20-Oct K.GFAFVQYVNER[166.11].N "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 14 1338.6596 0.95 59888 18423 2 1338.664836 670.3371 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 6 3540 - 174000 - - - 3.9069 - 2.176 0.028 - 438.1 1 2 0 0.0052 11 0 0 0 1.15E+06 1.21E+06 - - - 1.3495 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18425.18425.2 0.0143 20-Aug K.SVLWVSADGLR.V "sp|Q9Y6R0|NUMBL_HUMAN,tr|M0R0Q4|M0R0Q4_HUMAN,tr|M0QYC2|M0QYC2_HUMAN,tr|M0QZV7|M0QZV7_HUMAN,tr|A0A0C4DGH3|A0A0C4DGH3_HUMAN,tr|M0QXQ4|M0QXQ4_HUMAN" 6 1201.6455 3.89 59890 18425 2 1201.645885 601.83 Numb-like protein OS=Homo sapiens OX=9606 GN=NUMBL PE=1 SV=1 5.55 3540.2 - 161231 - - - 0.3021 - 1.926 0.333 - 157.4 1 2 0 0.0004 11 0 0 0 1.44E+06 3.71E+05 - - - 3.2736 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18432.18432.2 0.00136 16-Sep K.GIFLGDQWR.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1090.556 2.75 59895 18432 2 1090.556968 546.2853 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3541 - 2.42E+06 - - - 0.9069 - 1.587 0.374 - 298.2 1 2 0 0.001 9 0 0 0 1.32E+08 4.79E+07 - - - 3.1392 0.8735 230117_WJC_METTL3_WT_vs_EV_F07.18433.18433.2 5.03 12-Jun K.MIADFLR.E "sp|Q96R72|OR4K3_HUMAN,sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 4 864.4528 5.35 59896 18433 2 864.459998 433.2337 Olfactory receptor 4K3 OS=Homo sapiens OX=9606 GN=OR4K3 PE=3 SV=3 5.59 3541.1 - 449897 - - - 8.3741 - 1.377 0.18 - 188.6 1 2 0 0.0072 7 0 0 0 5.96E+07 1.11E+07 - - - 1.3819 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18436.18436.2 0.015 18-Jul K.APDFVFYAPR[166.11].L "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 1191.5952 1.05 59899 18436 2 1191.596147 596.8049 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 5.88 3541.3 - 265345 - - - 0.7821 - 1.459 0.407 - 174.9 1 2 0 0.0009 10 0 0 0 6.79E+06 6.45E+06 - - - 3.1012 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.18437.18437.2 0.0107 14-Jul K.LWGVIDVK.R "sp|Q9UHD1|CHRD1_HUMAN,tr|E9PHZ2|E9PHZ2_HUMAN" 2 928.5382 3.75 59900 18437 2 928.539382 465.2764 Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2 5.84 3541.4 - 232480 - - - 1.2697 - 1.481 0.318 - 138.6 1 2 0 0.0012 8 0 0 0 1.18E+07 3.14E+06 - - - 2.5738 0.997 230117_WJC_METTL3_WT_vs_EV_F07.18439.18439.2 0.0312 18-Aug K.LWTMPISSVR[166.11].F "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1198.6408 2.12 59902 18439 2 1198.642666 600.3277 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3541.6 - 133820 - - - 1.5693 - 1.762 0.102 - 189 1 2 0 0.0019 10 0 0 0 8.48E+06 3.99E+06 - - - 1.3749 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.18440.18440.2 0.000417 18-Aug R.YLYTLVITDK.E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1227.6751 1.5 59903 18440 2 1227.675432 614.8448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3541.7 - 133023 - - - 0.2778 - 1.761 0.287 - 141.8 1 2 0 0.0003 10 0 0 0 5.17E+08 3.45E+08 - - - 2.7402 1 230117_WJC_METTL3_WT_vs_EV_F07.18442.18442.2 0.00183 14/22 H.IISELILTAQER[166.11].D sp|Q96I24|FUBP3_HUMAN 1 1394.8009 1.85 59905 18442 2 1394.803367 698.4077 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3541.9 - 70446.7 - - - 1.8046 - 2.638 0.413 - 731.7 1 1 0 0.0025 12 0 0 0 4.29E+06 2.32E+06 - - - 4.6429 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.18447.18447.2 0.000566 16-Aug K.GIFLGDQWR[166.11].D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1100.5642 2.69 59908 18447 2 1100.565743 551.2894 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3542.5 - 1.19E+07 - - - 1.3575 - 1.612 0.286 - 207.7 1 2 0 0.0015 9 0 0 0 1.28E+08 4.77E+07 - - - 2.5343 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18448.18448.2 0.0391 18-Aug R.YLYTLVITDK[136.11].E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1235.6893 1.5 59909 18448 2 1235.691165 618.8519 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3542.6 - 6.67E+06 - - - 1.5166 - 1.626 0.391 - 166.8 1 2 0 0.0019 10 0 0 0 5.17E+08 3.45E+08 - - - 3.2853 0.976 230117_WJC_METTL3_WT_vs_EV_F07.18451.18451.2 0.00412 20-Nov R.LLDLVVQPVPR.P sp|Q8WYP5|ELYS_HUMAN 1 1247.7602 1.52 59912 18451 2 1247.76169 624.8874 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.84 3542.8 - 1.63E+06 - - - 1.2278 - 2.078 0.41 - 463.9 1 1 0 0.0015 11 0 0 0 7.41E+06 4.86E+06 - - - 4.0474 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.18452.18452.2 2.91 12-Jun K.MIADFLR[166.11].E "sp|Q96R72|OR4K3_HUMAN,sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 4 874.461 5.28 59913 18452 2 874.462582 438.2378 Olfactory receptor 4K3 OS=Homo sapiens OX=9606 GN=OR4K3 PE=3 SV=3 5.59 3542.9 - 1.55E+06 - - - 1.776 - 1.336 0.185 - 147.4 1 2 0 0.0016 7 0 0 0 5.96E+07 1.13E+07 - - - 1.3248 0.9656 230117_WJC_METTL3_WT_vs_EV_F07.18454.18454.2 0.000776 20-Nov R.LLDLVVQPVPR[166.11].P sp|Q8WYP5|ELYS_HUMAN 1 1257.7684 1.52 59915 18454 2 1257.770688 629.8915 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.84 3543.1 - 1.15E+06 - - - 1.7968 - 2.247 0.302 - 563.5 1 1 0 0.0023 11 0 0 0 7.41E+06 4.86E+06 - - - 3.461 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.18456.18456.2 0.000137 16-Aug K.YMAEALLLR.A sp|O94826|TOM70_HUMAN 1 1078.5845 1.08 59917 18456 2 1078.58778 540.2995 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 6 3543.2 - 874705 - - - 3.0392 - 1.541 0.465 - 191 1 2 0 0.0033 9 0 0 0 6.73E+06 6.25E+06 - - - 3.7255 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18457.18457.2 0.00226 20-Oct K.VMVTNVTSLLK.T "sp|Q9Y4G6|TLN2_HUMAN,sp|Q9Y490|TLN1_HUMAN,tr|A0A1B0GVU7|A0A1B0GVU7_HUMAN,tr|H0YMT1|H0YMT1_HUMAN" 4 1203.6897 0.3 59918 18457 2 1203.69297 602.8521 Talin-2 OS=Homo sapiens OX=9606 GN=TLN2 PE=1 SV=4 8.72 3543.4 - 852225 - - - 2.7208 - 1.967 0.391 - 252.7 1 2 0 0.0033 11 0 0 0 2.83E+06 9.49E+06 - - - 3.758 0.9714 230117_WJC_METTL3_WT_vs_EV_F07.18458.18458.2 0.0113 13/22 L.PLIPIVVEQTGR.G sp|Q16740|CLPP_HUMAN 1 1320.7765 1.62 59919 18458 2 1320.778053 661.3955 "ATP-dependent Clp protease proteolytic subunit, mitochondrial OS=Homo sapiens OX=9606 GN=CLPP PE=1 SV=1" 6.43 3543.5 - 838577 - - - 1.1486 - 2.163 0.357 - 387.1 1 1 0 0.0015 12 0 0 0 6.34E+06 3.91E+06 - - - 3.7073 0.9599 230117_WJC_METTL3_WT_vs_EV_F07.18460.18460.2 6.04E-05 13/22 H.IISELILTAQER.D sp|Q96I24|FUBP3_HUMAN 1 1384.7926 1.85 59921 18460 2 1384.796545 693.4036 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3543.7 - 669536 - - - 2.8632 - 2.028 0.425 - 277 1 1 0 0.004 12 0 0 0 4.29E+06 2.32E+06 - - - 4.0392 0.9027 230117_WJC_METTL3_WT_vs_EV_F07.18461.18461.2 0.0973 22-Oct H.IISELILTAQER[166.11].D sp|Q96I24|FUBP3_HUMAN 1 1394.8009 1.85 59922 18461 2 1394.805443 698.4077 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3543.9 - 413230 - - - 3.2929 - 1.991 0.283 - 342.9 1 1 0 0.0046 12 0 0 0 4.29E+06 2.32E+06 - - - 2.9417 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18463.18463.2 0.000524 22-Jul R.LVPVSFEDPEFK.S tr|F5GXE4|F5GXE4_HUMAN 1 1405.7129 5.74 59924 18463 2 1405.715811 703.8637 Arginyl-tRNA--protein transferase 1 OS=Homo sapiens OX=9606 GN=ATE1 PE=1 SV=1 4.14 3544.1 - 198502 - - - 2.0474 - 1.511 0.408 - 43.9 1 2 0 0.0029 12 0 0 0 2.14E+06 3.72E+05 - - - 3.1397 0.9735 230117_WJC_METTL3_WT_vs_EV_F07.18467.18467.2 3.58 12-Jun R.SILEYLR.V sp|Q8N1G4|LRC47_HUMAN 1 892.5018 1.5 59926 18467 2 892.500144 447.2582 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 5.72 3544.6 - 3.50E+06 - - - -1.8756 - 1.271 0.146 - 156.6 1 2 0 -0.0017 7 0 0 0 2.54E+07 1.69E+07 - - - 0.8787 1 230117_WJC_METTL3_WT_vs_EV_F07.18468.18468.2 3.94E-06 13/22 K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 999 59927 18468 2 1382.680364 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3544.8 - 937454 - - - -1.9281 - 2.443 0.456 - 485.6 1 2 0 -0.0027 12 0 0 0 1.38E+07 0.00E+00 - - - 4.7584 0.9888 230117_WJC_METTL3_WT_vs_EV_F07.18469.18469.2 2.18 16-Oct R.FLSGLELVK.Q "sp|Q96S44|PRPK_HUMAN,tr|Q5JZ02|Q5JZ02_HUMAN" 2 1004.5906 0.9 59928 18469 2 1004.593283 503.3026 EKC\KEOPS complex subunit TP53RK OS=Homo sapiens OX=9606 GN=TP53RK PE=1 SV=2 6 3544.9 - 3.08E+06 - - - 2.6379 - 1.617 0.032 - 201.9 1 2 0 0.0027 9 0 0 0 2.21E+07 2.47E+07 - - - 0.6668 0.987 230117_WJC_METTL3_WT_vs_EV_F07.18470.18470.2 2.8 12-Jun R.YDLWNLK.Y sp|Q9ULW3|ABT1_HUMAN 1 950.4862 0.67 59929 18470 2 950.489443 476.2504 Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1 5.83 3545 - 1.07E+06 - - - 3.4456 - 1.353 0.124 - 102.1 1 2 0 0.0033 7 0 0 0 8.43E+06 1.26E+07 - - - 0.9138 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.18471.18471.2 0.28 12-Aug R.YDLWNLK[136.11].Y sp|Q9ULW3|ABT1_HUMAN 1 958.5004 0.59 59930 18471 2 958.503182 480.2575 Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1 5.83 3545.1 - 1.00E+06 - - - 2.9358 - 1.522 0.28 - 188.8 1 2 0 0.0028 7 0 0 0 8.53E+06 1.44E+07 - - - 2.4391 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.18472.18472.2 0.000154 20-Sep K.FGEPVLAGFAR[166.11].S sp|O15067|PUR4_HUMAN 1 1172.6218 3.83 59931 18472 2 1172.626099 587.3182 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 6 3545.3 - 848500 - - - 3.6968 - 2.014 0.424 - 257 1 2 0 0.0043 11 0 0 0 3.70E+07 9.65E+06 - - - 4.0653 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18475.18475.2 0.147 14-Jul K.DVIEEYFK.C sp|P25398|RS12_HUMAN 1 1041.5019 3.31 59934 18475 2 1041.504277 521.7582 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.14 3545.7 - 679758 - - - 2.3034 - 1.827 0.333 - 165.6 1 2 0 0.0024 8 0 0 0 8.13E+06 2.45E+06 - - - 3.3174 0.9843 230117_WJC_METTL3_WT_vs_EV_F07.18476.18476.2 1.39 14-May K.IGGIFAFK.V "sp|P22307|SCP2_HUMAN,tr|H0YF61|H0YF61_HUMAN" 2 851.4905 1.46 59935 18476 2 851.490667 426.7525 Sterol carrier protein 2 OS=Homo sapiens OX=9606 GN=SCP2 PE=1 SV=2 8.75 3545.8 - 622567 - - - 0.1668 - 1.166 0.135 - 40.4 2 2 0 0.0001 8 0 0 0 4.66E+06 3.18E+06 - - - 0.3668 1 230117_WJC_METTL3_WT_vs_EV_F07.18478.18478.2 8.43E-10 13/26 K.FYGPEGPYGVFAGR.D sp|O00264|PGRC1_HUMAN 1 1515.7147 1.51 59937 18478 2 1515.715772 758.8646 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3546.1 - 528112 - - - 0.731 - 2.594 0.691 - 605.8 1 2 0 0.0011 14 0 0 0 3.22E+07 2.13E+07 - - - 6.5364 1 230117_WJC_METTL3_WT_vs_EV_F07.18482.18482.2 3.02E-10 26-Dec K.FYGPEGPYGVFAGR[166.11].D sp|O00264|PGRC1_HUMAN 1 1525.7229 1.51 59941 18482 2 1525.723835 763.8687 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3546.6 - 321818 - - - 0.5905 - 2.322 0.647 - 522 1 2 0 0.0009 14 0 0 0 3.22E+07 2.13E+07 - - - 5.9335 0.9929 230117_WJC_METTL3_WT_vs_EV_F07.18483.18483.2 0.391 20-Sep K.GLLPTPDEFPR.F sp|Q9C0J8|WDR33_HUMAN 1 1240.6452 2.29 59942 18483 2 1240.645537 621.3299 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 4.37 3546.7 - 925722 - - - 0.2813 - 1.068 0.227 - 100.2 1 2 0 0.0003 11 0 0 0 2.67E+06 1.17E+06 - - - 0.8955 1 230117_WJC_METTL3_WT_vs_EV_F07.18489.18489.2 0.000208 28-Sep R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 999 59947 18489 2 1484.908971 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3547.5 - 214202 - - - 0.7314 - 1.968 0.533 - 218.3 1 2 0 0.0011 15 0 0 0 3.02E+06 0.00E+00 - - - 4.6419 0.867 230117_WJC_METTL3_WT_vs_EV_F07.18490.18490.2 0.114 18-Sep S.GVAVSDGVIK.V "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PS23|E9PS23_HUMAN" 4 943.5338 2.05 59948 18490 2 943.534792 472.7742 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 5.84 3547.5 - 2.86E+06 - - - 1.0026 - 1.636 0.184 - 174.5 1 1 0 0.0009 10 0 0 0 3.33E+08 1.63E+08 - - - 1.7738 0.9885 230117_WJC_METTL3_WT_vs_EV_F07.18491.18491.2 0.189 14-Jul K.DLYSALIK.L sp|O75844|FACE1_HUMAN 1 921.5171 1.04 59949 18491 2 921.517183 461.7658 CAAX prenyl protease 1 homolog OS=Homo sapiens OX=9606 GN=ZMPSTE24 PE=1 SV=2 5.83 3547.6 - 2.10E+06 - - - 0.0532 - 1.076 0.185 - 142.6 1 2 0 0 8 0 0 0 2.18E+07 2.09E+07 - - - 0.6283 1 230117_WJC_METTL3_WT_vs_EV_F07.18492.18492.2 6.79E-05 18-Nov R.IPLNPYLNLH.S "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 1192.6604 - 59950 18492 2 1192.660917 597.3375 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.74 3547.6 - 2.08E+06 - - - 0.3966 - 2.197 0.522 - 475.3 1 1 0 0.0005 10 0 0 0 - - - - - 5.0934 0.9931 230117_WJC_METTL3_WT_vs_EV_F07.18494.18494.2 0.129 12-May K.FALPYIR.D "sp|P06132|DCUP_HUMAN,tr|Q5T446|Q5T446_HUMAN,tr|A0A1B0GVN9|A0A1B0GVN9_HUMAN,tr|H0Y5R6|H0Y5R6_HUMAN,tr|A0A494C0S8|A0A494C0S8_HUMAN,tr|A0A494C0Q8|A0A494C0Q8_HUMAN,tr|A0A494C085|A0A494C085_HUMAN" 7 878.5014 1.13 59952 18494 2 878.501039 440.258 Uroporphyrinogen decarboxylase OS=Homo sapiens OX=9606 GN=UROD PE=1 SV=2 8.75 3547.8 - 775274 - - - -0.4382 - 1.258 0.197 - 103.6 1 2 0 -0.0004 7 0 0 0 1.15E+07 1.02E+07 - - - 1.2232 0.999 230117_WJC_METTL3_WT_vs_EV_F07.18498.18498.2 0.00377 14-Aug R.GFGFVQFK[136.11].N "sp|Q9NW13|RBM28_HUMAN,tr|C9JE21|C9JE21_HUMAN" 2 936.4949 0.86 59954 18498 2 936.495177 469.2547 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 8.75 3548.2 - 1.78E+06 - - - 0.3075 - 1.508 0.317 - 210.6 1 2 0 0.0003 8 0 0 0 1.48E+07 1.71E+07 - - - 2.6212 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.18501.18501.2 0.0262 16-Aug R.ILFLDPSGK[136.11].V sp|O95881|TXD12_HUMAN 1 996.5735 1.12 59957 18501 2 996.574953 499.294 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3548.4 - 4.16E+06 - - - 1.4249 - 1.557 0.309 - 148.5 1 2 0 0.0014 9 0 0 0 5.14E+08 4.59E+08 - - - 2.6038 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18502.18502.2 0.000106 16-Nov R.ILFLDPSGK.V sp|O95881|TXD12_HUMAN 1 988.5593 1.12 59958 18502 2 988.562508 495.2869 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3548.4 - 3.80E+06 - - - 3.2117 - 1.956 0.438 - 324.2 1 2 0 0.0032 9 0 0 0 5.14E+08 4.59E+08 - - - 4.216 1 230117_WJC_METTL3_WT_vs_EV_F07.18503.18503.2 3.87E-05 13/18 K.IGSDVELLLR.T sp|Q5U5X0|LYRM7_HUMAN 1 1113.6394 1.25 59959 18503 2 1113.641935 557.827 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 4.37 3548.5 - 2.95E+06 - - - 2.2997 - 2.776 0.481 - 496.9 1 2 0 0.0026 10 0 0 0 3.09E+07 2.48E+07 - - - 5.4428 0.9694 230117_WJC_METTL3_WT_vs_EV_F07.18507.18507.2 0.076 16-Jul K.YMLPLDNLK.V "sp|Q9UQ16|DYN3_HUMAN,sp|P50570|DYN2_HUMAN,tr|E5RHK8|E5RHK8_HUMAN" 3 1105.5842 6.32 59963 18507 2 1105.579818 553.7994 Dynamin-3 OS=Homo sapiens OX=9606 GN=DNM3 PE=1 SV=4 5.83 3549 - 476029 - - - -3.9337 - 1.46 0.226 - 99.3 1 2 0 -0.0043 9 0 0 0 6.66E+06 1.05E+06 - - - 1.8037 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18514.18514.2 0.00078 16-Oct K.LEVDIPLVK.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1024.6168 2.04 59968 18514 2 1024.618251 513.3157 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3550 - 1.34E+06 - - - 1.3693 - 1.913 0.419 - 295.8 1 2 0 0.0014 9 0 0 0 7.33E+07 3.59E+07 - - - 4.0119 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18515.18515.2 0.0522 16-Oct K.LEVDIPLVK[136.11].S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1032.631 3.12 59969 18515 2 1032.632293 517.3228 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3550.1 - 766065 - - - 1.2057 - 1.915 0.362 - 233.9 1 2 0 0.0012 9 0 0 0 1.31E+08 4.19E+07 - - - 3.594 1 230117_WJC_METTL3_WT_vs_EV_F07.18517.18517.2 6.72E-05 20-Nov R.MLDMGFEPQIR[166.11].R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1345.6398 1.22 59971 18517 2 1345.64064 673.8272 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3550.4 - 1.25E+06 - - - 0.6257 - 2.275 0.503 - 499.1 1 2 0 0.0008 11 0 0 0 6.24E+07 5.10E+07 - - - 4.9795 1 230117_WJC_METTL3_WT_vs_EV_F07.18518.18518.2 6.48E-06 13/20 R.MLDMGFEPQIR.R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1335.6315 1.23 59972 18518 2 1335.633084 668.823 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3550.5 - 1.14E+06 - - - 1.165 - 2.352 0.576 - 664.8 1 2 0 0.0016 11 0 0 0 6.25E+07 5.10E+07 - - - 5.6085 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.18520.18520.2 0.0443 16-Sep K.ILLITEDLK.N sp|Q08752|PPID_HUMAN 1 1056.6431 2.92 59974 18520 2 1056.646086 529.3288 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 4.37 3550.7 - 971491 - - - 2.8609 - 1.945 0.228 - 247.7 1 2 0 0.003 9 0 0 0 1.56E+07 5.34E+06 - - - 2.6487 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18522.18522.2 3.32E-05 22-Nov K.GLTPSQIGVILR[166.11].D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1262.7586 0.82 59976 18522 2 1262.761074 632.3866 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3551 - 677392 - - - 1.9655 - 2.181 0.312 - 507 1 2 0 0.0025 12 0 0 0 1.64E+07 2.01E+07 - - - 3.3964 0.9575 230117_WJC_METTL3_WT_vs_EV_F07.18526.18526.2 3.35 16-May R.LLYGMALVR[166.11].F "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3R6|A0A7I2V3R6_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V4V0|A0A7I2V4V0_HUMAN,tr|A0A7I2V5R7|A0A7I2V5R7_HUMAN,tr|A0A7I2V653|A0A7I2V653_HUMAN,tr|A0A7I2YQI7|A0A7I2YQI7_HUMAN" 7 1044.6029 1.17 59980 18526 2 1044.606541 523.3087 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 8.75 3551.5 - 309002 - - - 3.4453 - 1.247 0.111 - 59.1 9 2 0 0.0036 9 0 0 0 6.68E+06 5.71E+06 - - - 0.0721 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.18531.18531.2 0.181 14-Aug R.EMVLEIIR.E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1001.558 1.26 59983 18531 2 1001.56025 501.7863 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3552.1 - 5.31E+06 - - - 2.2934 - 1.826 0.225 - 370.5 1 2 0 0.0023 8 0 0 0 1.84E+08 1.46E+08 - - - 2.5181 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.18532.18532.2 0.0357 14-Sep R.EMVLEIIR[166.11].E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1011.5662 1.26 59984 18532 2 1011.568489 506.7904 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3552.1 - 3.75E+06 - - - 2.2401 - 1.943 0.221 - 518 1 2 0 0.0023 8 0 0 0 1.84E+08 1.46E+08 - - - 2.6759 1 230117_WJC_METTL3_WT_vs_EV_F07.18536.18536.2 2.40E-05 16-Nov K.LYMVLITTK.N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 3 1080.6253 1.37 59988 18536 2 1080.627531 541.3199 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 8.59 3552.5 - 576825 - - - 2.0608 - 1.998 0.514 - 409.2 1 2 0 0.0022 9 0 0 0 8.52E+06 6.21E+06 - - - 4.8391 0.999 230117_WJC_METTL3_WT_vs_EV_F07.18538.18538.2 0.019 20-Sep R.LPPEFSPVIIK[136.11].E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1246.7417 0.26 59990 18538 2 1246.742367 624.3781 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6 3552.8 - 318194 - - - 0.5663 - 1.631 0.288 - 218.4 1 2 0 0.0007 11 0 0 0 1.48E+06 5.64E+06 - - - 2.4913 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.18544.18544.2 0.104 14-Sep K.VALLLLEK.E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 897.5899 1.32 59995 18544 2 897.591525 449.8022 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3553.5 - 773918 - - - 1.8048 - 1.886 0.214 - 284.6 1 2 0 0.0016 8 0 0 0 1.34E+07 1.01E+07 - - - 2.5346 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.18547.18547.2 0.156 16-Aug K.LSDGVAVLK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 900.528 2.39 59997 18547 2 900.529777 451.2713 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 3553.8 - 1.93E+06 - - - 1.9366 - 1.682 0.15 - 109.4 1 2 0 0.0017 9 0 0 0 1.20E+07 5.04E+06 - - - 1.6527 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18548.18548.2 0.00539 16-Nov R.LYSVSYLLK[136.11].D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1092.631 0.75 59998 18548 2 1092.632905 547.3228 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.5 3553.8 - 3.43E+06 - - - 1.6996 - 2.113 0.456 - 333.1 1 2 0 0.0019 9 0 0 0 2.71E+07 3.61E+07 - - - 4.5728 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18549.18549.2 2.73E-05 22-Nov K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 0.9 59999 18549 2 1252.752432 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3553.9 - 2.92E+06 - - - 1.6843 - 2.098 0.321 - 515.3 1 2 0 0.0021 12 0 0 0 3.77E+07 4.18E+07 - - - 3.3609 0.9938 230117_WJC_METTL3_WT_vs_EV_F07.18551.18551.2 0.328 14-Aug K.LLDLDALR[166.11].K "sp|P30622|CLIP1_HUMAN,tr|A0A3B3ITA2|A0A3B3ITA2_HUMAN" 2 937.5472 1.28 60001 18551 2 937.548848 469.7809 CAP-Gly domain-containing linker protein 1 OS=Homo sapiens OX=9606 GN=CLIP1 PE=1 SV=2 4.21 3554 - 1.04E+06 - - - 1.7556 - 1.583 0.057 - 151.1 1 2 0 0.0016 8 0 0 0 4.66E+06 3.65E+06 - - - 0.8468 0.9395 230117_WJC_METTL3_WT_vs_EV_F07.18552.18552.2 5.31 14-Oct V.ILSILLSK.A "sp|Q6UXB4|CLC4G_HUMAN,sp|Q02040|AK17A_HUMAN,tr|A0A7I2V4C7|A0A7I2V4C7_HUMAN,tr|M0R277|M0R277_HUMAN,tr|A0A7I2V4U5|A0A7I2V4U5_HUMAN" 5 885.5899 1.03 60002 18552 2 885.591552 443.8022 C-type lectin domain family 4 member G OS=Homo sapiens OX=9606 GN=CLEC4G PE=1 SV=1 8.75 3554.2 - 841900 - - - 1.8598 - 1.937 0.224 - 274.2 1 1 0 0.0016 8 0 0 0 5.23E+06 5.07E+06 - - - 2.6889 1 230117_WJC_METTL3_WT_vs_EV_F07.18555.18555.2 7.80E-05 22-Nov K.AFAVGVQQVLLK[136.11].V sp|O95373|IPO7_HUMAN 1 1279.7744 2.02 60005 18555 2 1279.777394 640.8945 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 8.8 3554.6 - 334734 - - - 2.3723 - 2.479 0.549 - 397.5 1 2 0 0.003 12 0 0 0 1.09E+07 5.41E+06 - - - 5.4837 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.18562.18562.2 0.00666 14-Jul K.VALLLLEK[136.11].E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 905.6041 1.34 60011 18562 2 905.605504 453.8093 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3555.6 - 391743 - - - 1.5448 - 1.709 0.105 - 116 1 2 0 0.0014 8 0 0 0 1.36E+07 1.01E+07 - - - 1.4324 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.18566.18566.2 0.0354 12-Jun R.EIFITFR.V sp|Q96EY1|DNJA3_HUMAN 1 924.5069 1.93 60014 18566 2 924.509938 463.2607 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.1 3555.9 - 2.88E+06 - - - 3.2828 - 1.372 0.262 - 136.5 1 2 0 0.003 7 0 0 0 1.73E+07 8.95E+06 - - - 1.9773 0.997 230117_WJC_METTL3_WT_vs_EV_F07.18567.18567.2 0.576 16-Sep R.SLIAEVLVK.L sp|O95969|SG1D2_HUMAN 1 970.6063 999 60015 18567 2 970.608777 486.3104 Secretoglobin family 1D member 2 OS=Homo sapiens OX=9606 GN=SCGB1D2 PE=2 SV=1 5.72 3556 - 2.74E+06 - - - 2.5695 - 1.556 0.182 - 216.5 1 2 0 0.0025 9 0 0 0 1.14E+07 0.00E+00 - - - 1.6635 0.999 230117_WJC_METTL3_WT_vs_EV_F07.18568.18568.2 0.121 12-Jun R.EIFITFR[166.11].V sp|Q96EY1|DNJA3_HUMAN 1 934.5152 1.94 60016 18568 2 934.516353 468.2649 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.1 3556.1 - 1.89E+06 - - - 1.2627 - 1.564 0.265 - 139.5 1 2 0 0.0012 7 0 0 0 1.73E+07 8.95E+06 - - - 2.415 0.988 230117_WJC_METTL3_WT_vs_EV_F07.18570.18570.2 0.0689 14-Jul K.NGLDVLFK[136.11].V "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 912.516 1.79 60018 18570 2 912.518416 457.2653 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 5.84 3556.4 - 868525 - - - 2.6279 - 1.279 0.113 - 122.3 1 2 0 0.0024 8 0 0 0 7.35E+06 4.11E+06 - - - 0.617 0.9457 230117_WJC_METTL3_WT_vs_EV_F07.18573.18573.2 1.39 12-May K.SMLNFLK.K "sp|Q7Z6Z7|HUWE1_HUMAN,tr|A0A087X1S3|A0A087X1S3_HUMAN" 2 851.4575 0.97 60021 18573 2 851.460205 426.736 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 8.47 3556.7 - 795095 - - - 3.1652 - 1.002 0.101 - 84 1 2 0 0.0027 7 0 0 0 3.57E+06 3.69E+06 - - - -0.2075 0.9951 230117_WJC_METTL3_WT_vs_EV_F07.18574.18574.2 0.457 14-Sep R.LYLLQGIR.N "sp|Q9Y5A7|NUB1_HUMAN,tr|H3BM74|H3BM74_HUMAN,tr|H3BM14|H3BM14_HUMAN" 3 974.5913 2.44 60022 18574 2 974.595964 488.3029 NEDD8 ultimate buster 1 OS=Homo sapiens OX=9606 GN=NUB1 PE=1 SV=2 8.75 3556.9 - 1.25E+06 - - - 4.7835 - 1.795 0.243 - 258.1 1 2 0 0.0047 8 0 0 0 4.40E+06 1.81E+06 - - - 2.5987 1 230117_WJC_METTL3_WT_vs_EV_F07.18575.18575.2 0.000137 18-Oct K.VFLSGMPELR.L "sp|Q9Y6Q5|AP1M2_HUMAN,sp|Q9BXS5|AP1M1_HUMAN,tr|E7ENJ6|E7ENJ6_HUMAN,tr|K7EJL1|K7EJL1_HUMAN,tr|K7EJJ1|K7EJJ1_HUMAN,tr|K7EMG5|K7EMG5_HUMAN,tr|K7EPR4|K7EPR4_HUMAN" 7 1147.606 1.1 60023 18575 2 1147.608315 574.8103 AP-1 complex subunit mu-2 OS=Homo sapiens OX=9606 GN=AP1M2 PE=1 SV=4 5.97 3557 - 591179 - - - 2.0477 - 2.053 0.508 - 365.1 1 2 0 0.0023 10 0 0 0 4.74E+06 4.30E+06 - - - 4.8001 1 230117_WJC_METTL3_WT_vs_EV_F07.18582.18582.2 4.85E-07 20-Sep K.LVNIYDSMPLR.Y sp|Q9UBQ6|EXTL2_HUMAN 1 1319.6908 0.76 60030 18582 2 1319.697703 660.8527 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 5.84 3557.9 - 163620 - - - 5.2626 - 2.305 0.484 - 301.7 1 2 0 0.0069 11 0 0 0 8.86E+05 1.16E+06 - - - 4.8727 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18586.18586.2 0.000285 18-Jul K.FYALDPSFPR[166.11].M sp|Q08J23|NSUN2_HUMAN 1 1221.6058 2.11 60033 18586 2 1221.607605 611.8102 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3558.4 - 383737 - - - 1.4948 - 1.525 0.377 - 141.5 1 2 0 0.0018 10 0 0 0 9.00E+06 4.26E+06 - - - 3.0029 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.18587.18587.2 0.02 12-Aug R.NYLSIFR.K sp|P07384|CAN1_HUMAN 1 911.4865 17.95 60034 18587 2 911.487876 456.7505 Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1 8.75 3558.5 - 1.08E+06 - - - 1.5074 - 1.607 0.283 - 251.4 1 2 0 0.0014 7 0 0 0 1.49E+07 8.28E+05 - - - 2.6339 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.18590.18590.2 0.392 18-Nov K.ALQEFDLALR[166.11].G "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1184.6429 0.64 60037 18590 2 1184.645215 593.3287 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 4.37 3558.8 - 648797 - - - 1.9601 - 1.841 0.268 - 422.4 1 2 0 0.0023 10 0 0 0 5.75E+06 9.00E+06 - - - 2.7233 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.18593.18593.2 0.221 12-Jul R.DLFALAR[166.11].K sp|Q9Y4W6|AFG32_HUMAN 1 814.4577 1.38 60040 18593 2 814.459069 408.2361 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.84 3559.2 - 452801 - - - 1.7324 - 1.366 0.179 - 221.2 1 2 0 0.0014 7 0 0 0 1.04E+07 7.51E+06 - - - 1.3509 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.18595.18595.2 0.000346 14-Jul K.NGLDVLFK.V "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 904.5018 1.47 60042 18595 2 904.50086 453.2582 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 5.84 3559.5 - 343436 - - - -1.0591 - 1.425 0.354 - 132.5 1 2 0 -0.001 8 0 0 0 5.70E+06 3.89E+06 - - - 2.7235 0.993 230117_WJC_METTL3_WT_vs_EV_F07.18599.18599.2 4.90E-05 18-Oct K.FYALDPSFPR.M sp|Q08J23|NSUN2_HUMAN 1 1211.5975 1.63 60045 18599 2 1211.592227 606.806 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3560 - 675814 - - - -4.3595 - 1.728 0.471 - 317.6 1 2 0 -0.0053 10 0 0 0 5.94E+06 3.63E+06 - - - 4.0449 0.9234 230117_WJC_METTL3_WT_vs_EV_F07.18601.18601.2 0.00581 13/20 F.IGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1068.6543 6.5 60046 18601 2 1068.658563 535.3344 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 3560.2 - 3.46E+06 - - - 3.9929 - 2.486 0.356 - 435.2 1 1 0 0.0043 11 0 0 0 1.89E+08 2.91E+07 - - - 4.1327 0.9692 230117_WJC_METTL3_WT_vs_EV_F07.18608.18608.2 0.489 12-Jul R.DLFALAR.K sp|Q9Y4W6|AFG32_HUMAN 1 804.4494 1.38 60053 18608 2 804.452686 403.232 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.84 3561.1 - 619080 - - - 4.0997 - 1.233 0.121 - 224.4 1 2 0 0.0033 7 0 0 0 1.04E+07 7.51E+06 - - - 0.5973 1 230117_WJC_METTL3_WT_vs_EV_F07.18610.18610.2 0.000813 18-Dec K.TLVQILTEPR.N sp|O76031|CLPX_HUMAN 1 1168.6816 1.91 60055 18610 2 1168.68705 585.3481 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3561.3 - 392109 - - - 4.6865 - 2.412 0.452 - 695.8 1 2 0 0.0055 10 0 0 0 1.59E+07 8.30E+06 - - - 4.8354 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.18612.18612.2 0.00108 16-Oct K.LLQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1118.5748 12.47 60057 18612 2 1118.579437 560.2947 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3561.6 - 284079 - - - 4.1338 - 1.933 0.425 - 311.5 1 2 0 0.0046 9 0 0 0 3.77E+08 3.02E+07 - - - 4.0853 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18615.18615.2 1.11E-05 30-Sep K.IFVGGLSANTVVEDVK.Q "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|J3KTC1|J3KTC1_HUMAN" 5 1646.8879 3.97 60060 18615 2 1646.890259 824.4512 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.37 3562 - 143101 - - - 1.4099 - 1.926 0.506 - 169.9 1 2 0 0.0023 16 0 0 0 9.00E+05 2.27E+05 - - - 4.389 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.18618.18618.2 0.247 14-Aug K.SIGDIFLK[136.11].Y "sp|Q9H8V3|ECT2_HUMAN,tr|H7C3G1|H7C3G1_HUMAN" 2 899.5208 0.96 60061 18618 2 899.522354 450.7677 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 5.55 3562.4 - 1.53E+06 - - - 1.762 - 1.344 0.347 - 164 1 2 0 0.0016 8 0 0 0 1.40E+07 1.47E+07 - - - 2.4951 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18619.18619.2 0.00691 12-Sep K.C[160.03]ALDFFR.Q sp|P51970|NDUA8_HUMAN 1 927.4273 1.37 60062 18619 2 927.429478 464.7209 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3562.5 - 548054 - - - 2.3775 - 1.806 0.383 - 370.8 1 2 0 0.0022 7 0 0 0 1.73E+07 1.27E+07 - - - 3.7421 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18626.18626.2 2.30E-05 16-Nov R.ELGELIPLR[166.11].Q "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1048.6156 1.17 60067 18626 2 1048.618763 525.3151 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.53 3563.2 - 985963 - - - 3.0011 - 2.125 0.398 - 483.8 1 2 0 0.0031 9 0 0 0 1.44E+07 1.23E+07 - - - 4.1603 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.18627.18627.2 0.0242 12-Aug K.C[160.03]ALDFFR[166.11].Q sp|P51970|NDUA8_HUMAN 1 937.4355 1.37 60068 18627 2 937.438182 469.725 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3563.3 - 955174 - - - 2.8151 - 1.52 0.3 - 349.1 1 2 0 0.0026 7 0 0 0 1.73E+07 1.27E+07 - - - 2.5827 0.9943 230117_WJC_METTL3_WT_vs_EV_F07.18629.18629.2 0.0275 12-Jun R.TIFSYFK.G sp|Q9UJV9|DDX41_HUMAN 1 904.4695 1.02 60070 18629 2 904.471483 453.242 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 8.26 3563.5 - 684888 - - - 2.2422 - 1.099 0.228 - 108.3 1 2 0 0.002 7 0 0 0 2.10E+07 2.06E+07 - - - 1.0235 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18632.18632.2 0.00261 16-Nov K.LALFQAIGK.E "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 959.5804 2.19 60073 18632 2 959.582602 480.7975 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 8.75 3563.9 - 581409 - - - 2.2916 - 2.193 0.335 - 259.2 1 2 0 0.0022 9 0 0 0 5.14E+06 2.35E+06 - - - 3.7864 1 230117_WJC_METTL3_WT_vs_EV_F07.18633.18633.2 0.000487 18-Nov K.TLVQILTEPR[166.11].N sp|O76031|CLPX_HUMAN 1 1178.6898 1.91 60074 18633 2 1178.693646 590.3522 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3564 - 463218 - - - 3.2265 - 2.455 0.425 - 496.4 1 2 0 0.0038 10 0 0 0 1.58E+07 8.25E+06 - - - 4.6858 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18634.18634.2 0.00126 22-Sep K.VIGPEPTGFLLK.F sp|Q8IUH4|ZDH13_HUMAN 1 1269.7333 0.77 60075 18634 2 1269.733551 635.8739 Palmitoyltransferase ZDHHC13 OS=Homo sapiens OX=9606 GN=ZDHHC13 PE=1 SV=3 5.97 3564.1 - 459698 - - - 0.2174 - 1.819 0.372 - 217.9 1 2 0 0.0003 12 0 0 0 5.27E+06 6.80E+06 - - - 3.3627 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.18638.18638.2 0.497 20-Aug R.LPPEFSPVIIK.E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1238.7275 0.61 60079 18638 2 1238.729504 620.371 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6 3564.6 - 275772 - - - 1.6493 - 1.598 0.23 - 107.2 1 2 0 0.002 11 0 0 0 6.22E+06 1.02E+07 - - - 2.0072 0.9178 230117_WJC_METTL3_WT_vs_EV_F07.18644.18644.2 0.029 14/20 F.IGAIAIGDLVK[136.11].S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1076.6685 6.5 60083 18644 2 1076.671902 539.3415 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 3565.4 - 3.13E+06 - - - 3.1635 - 2.279 0.245 - 441.6 1 1 0 0.0034 11 0 0 0 1.89E+08 2.91E+07 - - - 3.0779 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18645.18645.2 1.56E-05 18-Nov K.LGMNLMNELK.Q "sp|Q16890|TPD53_HUMAN,tr|E9PNK6|E9PNK6_HUMAN,tr|E9PNQ9|E9PNQ9_HUMAN,tr|E9PPQ1|E9PPQ1_HUMAN,tr|J3KNE7|J3KNE7_HUMAN" 5 1161.5886 1.74 60084 18645 2 1161.591958 581.8016 Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1 6 3565.5 - 528268 - - - 2.89 - 2.268 0.416 - 283.3 1 2 0 0.0034 10 0 0 0 4.21E+06 2.42E+06 - - - 4.3983 1 230117_WJC_METTL3_WT_vs_EV_F07.18657.18657.2 2.02E-05 24-Nov K.LFPDTPLALDANK[136.11].K sp|Q12906|ILF3_HUMAN 1 1421.7646 0.92 60096 18657 2 1421.774094 711.8896 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3567 - 196739 - - - 6.691 - 2.129 0.498 - 388 1 2 0 0.0095 13 0 0 0 2.57E+06 2.78E+06 - - - 4.6556 0.9429 230117_WJC_METTL3_WT_vs_EV_F07.18660.18660.2 0.061 16-Jul R.GFIVESVLR.N sp|Q86UQ0|ZN589_HUMAN 1 1018.5811 2.39 60098 18660 2 1018.588232 510.2978 Zinc finger protein 589 OS=Homo sapiens OX=9606 GN=ZNF589 PE=1 SV=1 6 3567.4 - 109891 - - - 6.9715 - 1.624 0.154 - 120.4 1 2 0 0.0071 9 0 0 0 5.88E+06 2.46E+06 - - - 1.579 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.18663.18663.2 0.336 14-Jul R.LLLEEIYR[166.11].G "sp|Q9Y2P8|RCL1_HUMAN,tr|Q5VZU2|Q5VZU2_HUMAN,tr|Q5VZU3|Q5VZU3_HUMAN" 3 1057.6047 0.61 60100 18663 2 1057.606691 529.8096 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 4.53 3567.7 - 1.39E+06 - - - 1.8665 - 1.591 0.202 - 158.1 1 2 0 0.002 8 0 0 0 8.57E+06 1.40E+07 - - - 1.9328 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18667.18667.2 1.87E-06 13/24 K.LFPDTPLALDANK.K sp|Q12906|ILF3_HUMAN 1 1413.7504 0.92 60104 18667 2 1413.754554 707.8825 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3568.1 - 712070 - - - 2.9517 - 2.14 0.465 - 376.2 1 2 0 0.0042 13 0 0 0 3.23E+06 3.49E+06 - - - 4.4268 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.18670.18670.2 0.0716 18-Sep K.YPALIGNLVK[136.11].C "sp|Q9BYC9|RM20_HUMAN,tr|I3L2X1|I3L2X1_HUMAN" 2 1094.6579 1.26 60107 18670 2 1094.662987 548.3362 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 8.59 3568.5 - 428599 - - - 4.6188 - 2.099 0.387 - 173 1 2 0 0.0051 10 0 0 0 6.42E+06 5.08E+06 - - - 3.9674 0.9969 230117_WJC_METTL3_WT_vs_EV_F07.18672.18672.2 0.0063 18-Dec R.LGLLGLPAPK.N sp|Q99459|CDC5L_HUMAN 1 977.6274 1.14 60109 18672 2 977.631279 489.821 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3568.8 - 422815 - - - 4.0158 - 2.4 0.141 - 356 1 2 0 0.0039 10 0 0 0 5.81E+07 5.11E+07 - - - 2.5249 0.995 230117_WJC_METTL3_WT_vs_EV_F07.18673.18673.2 2.47E-05 18-Sep K.GPFVTWQVVR.D "sp|Q12789|TF3C1_HUMAN,tr|H3BRD0|H3BRD0_HUMAN" 2 1187.6451 6.57 60110 18673 2 1187.652542 594.8298 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 9.75 3568.9 - 414307 - - - 6.2426 - 1.762 0.465 - 240.1 1 2 0 0.0074 10 0 0 0 3.17E+06 4.82E+05 - - - 4.0543 1 230117_WJC_METTL3_WT_vs_EV_F07.18686.18686.2 1.36E-06 20-Dec K.LGLENAEALIR.L sp|P10155|RO60_HUMAN 1 1197.6717 3.41 60122 18686 2 1197.675153 599.8431 60 kDa SS-A\Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2 4.53 3570.5 - 1.59E+06 - - - 2.8522 - 2.777 0.435 - 423.5 1 2 0 0.0034 11 0 0 0 2.01E+07 5.90E+06 - - - 5.0159 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18687.18687.2 0.00918 13/22 K.YILAATLDNTLK[136.11].L sp|P61964|WDR5_HUMAN 1 1342.7588 2.06 60123 18687 2 1342.761877 672.3867 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 5.83 3570.6 - 1.29E+06 - - - 2.3154 - 2.392 0.412 - 470.7 1 2 0 0.0031 12 0 0 0 1.57E+07 7.65E+06 - - - 4.3778 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.18688.18688.2 0.00229 12-Jun R.VWSDFLR.V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 921.4709 2.4 60124 18688 2 921.473401 461.7427 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.81 3570.7 - 875292 - - - 2.7662 - 1.346 0.338 - 173.9 1 2 0 0.0025 7 0 0 0 9.46E+06 3.93E+06 - - - 2.4782 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.18690.18690.2 0.000127 20-Dec K.LGLENAEALIR[166.11].L sp|P10155|RO60_HUMAN 1 1207.68 3.71 60126 18690 2 1207.685774 604.8473 60 kDa SS-A\Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2 4.53 3571 - 730500 - - - 4.7753 - 2.249 0.4 - 319.4 1 2 0 0.0058 11 0 0 0 1.80E+07 4.85E+06 - - - 4.1861 1 230117_WJC_METTL3_WT_vs_EV_F07.18694.18694.2 7.41E-08 19/28 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 1.47 60130 18694 2 1458.760817 730.386 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3571.5 - 487967 - - - 2.3033 - 3.746 0.58 - 1500.9 1 2 0 0.0034 15 0 0 0 6.23E+07 4.24E+07 - - - 6.5708 0.9852 230117_WJC_METTL3_WT_vs_EV_F07.18695.18695.2 0.829 12-Jul K.EVILPIK.V sp|Q4G0P3|HYDIN_HUMAN 1 810.5215 1.48 60131 18695 2 810.523097 406.268 Hydrocephalus-inducing protein homolog OS=Homo sapiens OX=9606 GN=HYDIN PE=1 SV=3 6.1 3571.6 - 470177 - - - 1.9814 - 1.331 0.044 - 195.6 1 2 0 0.0016 7 0 0 0 1.13E+07 7.66E+06 - - - 0.2715 1 230117_WJC_METTL3_WT_vs_EV_F07.18696.18696.2 7.00E-05 18/28 R.LPAAGVGDMVMATVK[136.11].K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1466.7717 1.47 60132 18696 2 1466.77348 734.3931 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3571.7 - 401156 - - - 1.2429 - 3.734 0.555 - 1145.6 1 2 0 0.0018 15 0 0 0 6.23E+07 4.24E+07 - - - 6.3787 0.9779 230117_WJC_METTL3_WT_vs_EV_F07.18697.18697.2 3.07 12-Jul K.DLLLPIK[136.11].T "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 3 818.5357 1.5 60133 18697 2 818.53764 410.2751 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 5.84 3571.9 - 340173 - - - 2.3811 - 1.397 0.001 - 210.7 1 2 0 0.0019 7 0 0 0 1.13E+07 7.50E+06 - - - 0.1071 0.9818 230117_WJC_METTL3_WT_vs_EV_F07.18698.18698.2 2.43 20-Aug R.FLSAEAIGIMR[166.11].R sp|Q16512|PKN1_HUMAN 1 1216.6513 2.62 60134 18698 2 1216.652169 609.333 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 6 3572 - 378089 - - - 0.674 - 1.473 0.024 - 128.2 2 2 0 0.0008 11 0 0 0 4.99E+06 1.90E+06 - - - 0.1313 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18705.18705.2 4.54E-05 20-Sep R.IFVFEPPPGVK.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 1228.6856 1.88 60140 18705 2 1228.689446 615.3501 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3572.9 - 498320 - - - 3.1334 - 2.007 0.459 - 275.2 1 2 0 0.0039 11 0 0 0 2.83E+07 1.51E+07 - - - 4.3145 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.18706.18706.2 0.0228 18-Oct R.LGLLGLPAPK[136.11].N sp|Q99459|CDC5L_HUMAN 1 985.6416 1.14 60141 18706 2 985.644323 493.8281 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3572.9 - 6.83E+06 - - - 2.8104 - 2.03 0.295 - 188.8 1 2 0 0.0028 10 0 0 0 5.81E+07 5.11E+07 - - - 3.1953 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.18708.18708.2 2.43E-05 14-Oct K.MDELQLFR.G "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0T971|A0A7P0T971_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7P0Z4D1|A0A7P0Z4D1_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0T946|A0A7P0T946_HUMAN,tr|A0A7P0TBK7|A0A7P0TBK7_HUMAN" 14 1050.5168 0.98 60143 18708 2 1050.51997 526.2657 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.37 3573.1 - 1.40E+06 - - - 3.0023 - 2.216 0.252 - 504.6 1 2 0 0.0032 8 0 0 0 9.11E+06 9.26E+06 - - - 3.3011 0.9548 230117_WJC_METTL3_WT_vs_EV_F07.18709.18709.2 0.594 12-Apr R.VWSDFLR[166.11].V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 931.4791 2.38 60144 18709 2 931.481454 466.7468 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.81 3573.1 - 1.37E+06 - - - 2.5035 - 1.082 0.126 - 45.3 17 2 0 0.0023 7 0 0 0 9.27E+06 3.89E+06 - - - -0.329 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.18712.18712.2 0.00899 14-Jul K.YLELLGYR.K "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 7 1025.5546 1.71 60147 18712 2 1025.557873 513.7846 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6 3573.4 - 1.08E+06 - - - 3.209 - 1.586 0.321 - 176.4 1 2 0 0.0033 8 0 0 0 7.29E+06 4.27E+06 - - - 2.8019 1 230117_WJC_METTL3_WT_vs_EV_F07.18713.18713.2 8.95E-06 13/20 R.LYEAYLPETFR.R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1400.6976 2.41 60148 18713 2 1400.705144 701.3561 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3573.5 - 1.02E+06 - - - 5.3738 - 2.421 0.497 - 685.6 1 2 0 0.0075 11 0 0 0 2.75E+07 1.14E+07 - - - 5.1014 0.996 230117_WJC_METTL3_WT_vs_EV_F07.18715.18715.2 0.00135 14-Oct K.YLELLGYR[166.11].K "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 7 1035.5629 1.72 60150 18715 2 1035.567072 518.7887 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6 3573.7 - 739095 - - - 4.0751 - 1.967 0.164 - 389.2 1 2 0 0.0042 8 0 0 0 7.29E+06 4.23E+06 - - - 2.2913 0.9958 230117_WJC_METTL3_WT_vs_EV_F07.18719.18719.2 0.617 12-Aug K.IAFIAWK[136.11].S "sp|Q5UIP0|RIF1_HUMAN,tr|H7BZN3|H7BZN3_HUMAN" 2 855.5098 1.55 60154 18719 2 855.510386 428.7622 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 8.75 3574.2 - 373295 - - - 0.6733 - 1.45 0.13 - 176 1 2 0 0.0006 7 0 0 0 1.54E+06 9.92E+05 - - - 1.1783 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.18726.18726.2 0.0325 20-Aug R.IFVFEPPPGVK[136.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 1236.6998 1.92 60160 18726 2 1236.705468 619.3572 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3575.1 - 436008 - - - 4.5864 - 1.807 0.338 - 156.5 1 2 0 0.0057 11 0 0 0 2.91E+07 1.51E+07 - - - 3.1363 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.18727.18727.2 0.481 14-Aug K.MDELQLFR[166.11].G "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0T971|A0A7P0T971_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7P0Z4D1|A0A7P0Z4D1_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0T946|A0A7P0T946_HUMAN,tr|A0A7P0TBK7|A0A7P0TBK7_HUMAN" 14 1060.5251 0.98 60161 18727 2 1060.529573 531.2698 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.37 3575.1 - 3.64E+06 - - - 4.2309 - 1.975 0.262 - 326.2 1 2 0 0.0045 8 0 0 0 9.11E+06 9.26E+06 - - - 3.0273 1 230117_WJC_METTL3_WT_vs_EV_F07.18728.18728.2 0.000214 20-Dec R.LYEAYLPETFR[166.11].R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1410.7059 2.41 60162 18728 2 1410.709629 706.3602 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3575.2 - 1.95E+06 - - - 2.6526 - 2.33 0.502 - 438.6 1 2 0 0.0037 11 0 0 0 2.75E+07 1.14E+07 - - - 5.0359 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.18731.18731.2 0.0195 14-Jul R.WVVPVLPK.G "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 936.5797 1.97 60165 18731 2 936.582752 469.2971 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3575.6 - 882753 - - - 3.2864 - 1.565 0.321 - 174.8 1 2 0 0.0031 8 0 0 0 6.00E+06 3.05E+06 - - - 2.7617 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18732.18732.2 0.00753 18-Dec K.TNVALMC[160.03]MLR[166.11].E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1217.5958 1.08 60166 18732 2 1217.599239 609.8052 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 7.91 3575.7 - 875399 - - - 2.8039 - 2.211 0.434 - 644.2 1 2 0 0.0034 10 0 0 0 3.10E+06 2.87E+06 - - - 4.4602 0.997 230117_WJC_METTL3_WT_vs_EV_F07.18735.18735.2 0.0536 12-Jul R.LQFLFAK.D "sp|Q7Z3K3|POGZ_HUMAN,tr|H0YCT3|H0YCT3_HUMAN" 2 865.5062 1.31 60169 18735 2 865.508963 433.7604 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 8.75 3576.1 - 618933 - - - 3.2212 - 1.479 0.238 - 142.7 1 2 0 0.0028 7 0 0 0 3.15E+06 2.41E+06 - - - 2.0381 1 230117_WJC_METTL3_WT_vs_EV_F07.18736.18736.2 6.05E-06 20-Oct K.VIAEDEVLWYR.L "sp|Q8N3Y1|FBXW8_HUMAN,tr|A0A499FIY5|A0A499FIY5_HUMAN" 2 1391.7085 0.9 60170 18736 2 1391.709159 696.8615 F-box\WD repeat-containing protein 8 OS=Homo sapiens OX=9606 GN=FBXW8 PE=1 SV=2 4.14 3576.2 - 574818 - - - 0.462 - 2.239 0.491 - 335.3 1 2 0 0.0006 11 0 0 0 1.54E+06 1.70E+06 - - - 4.8478 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.18742.18742.2 0.059 12-Jul R.LQFLFAK[136.11].D "sp|Q7Z3K3|POGZ_HUMAN,tr|H0YCT3|H0YCT3_HUMAN" 2 873.5204 1.41 60176 18742 2 873.522913 437.7675 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 8.75 3577 - 321653 - - - 2.9055 - 1.543 0.271 - 126.5 1 2 0 0.0025 7 0 0 0 3.15E+06 2.22E+06 - - - 2.4161 1 230117_WJC_METTL3_WT_vs_EV_F07.18743.18743.2 0.000325 20-Dec K.LALDMEIATYR.K "sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|Q14CN4|K2C72_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 4 1294.6591 5.72 60177 18743 2 1294.65767 648.3368 "Keratin, type II cytoskeletal 74 OS=Homo sapiens OX=9606 GN=KRT74 PE=1 SV=2" 4.37 3577.1 - 312936 - - - -1.1223 - 2.464 0.478 - 557 1 2 0 -0.0015 11 0 0 0 1.24E+06 2.17E+05 - - - 5.0106 0.9887 230117_WJC_METTL3_WT_vs_EV_F07.18746.18746.2 0.543 12-Jun R.LFLEFER.K "sp|O43663|PRC1_HUMAN,sp|Q96I25|SPF45_HUMAN,tr|H0YL53|H0YL53_HUMAN" 3 952.5018 2.23 60179 18746 2 952.505705 477.2582 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 3577.6 - 1.04E+06 - - - 4.0808 - 1.212 0.231 - 122.5 1 2 0 0.0039 7 0 0 0 1.05E+07 4.71E+06 - - - 1.3552 1 230117_WJC_METTL3_WT_vs_EV_F07.18748.18748.2 5.10E-08 19/30 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 14.3 60181 18748 2 1686.899877 844.4543 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3577.8 - 3.27E+06 - - - 3.4335 - 3.389 0.557 - 1020.4 1 2 0 0.0058 16 0 0 0 2.83E+07 1.98E+06 - - - 6.1539 0.9927 230117_WJC_METTL3_WT_vs_EV_F07.18749.18749.2 0.026 16-Aug R.TTLLPGLLK.T sp|Q9NSD9|SYFB_HUMAN 1 954.6114 3.21 60182 18749 2 954.615228 478.313 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 8.41 3578 - 1.81E+06 - - - 4.0435 - 1.353 0.243 - 190.6 1 2 0 0.0039 9 0 0 0 1.31E+07 4.07E+06 - - - 1.7092 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.18750.18750.2 0.0629 14-Sep R.EALAFIIR[166.11].S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 941.5574 1.04 60183 18750 2 941.561394 471.786 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3578.1 - 1.78E+06 - - - 4.2716 - 1.8 0.279 - 326.8 1 2 0 0.004 8 0 0 0 1.22E+07 1.17E+07 - - - 2.8732 1 230117_WJC_METTL3_WT_vs_EV_F07.18751.18751.2 0.000416 18-Dec R.EDIVVPVYLR.E "sp|P51784|UBP11_HUMAN,tr|G5E9A6|G5E9A6_HUMAN" 2 1201.6707 7.29 60184 18751 2 1201.676465 601.8426 Ubiquitin carboxyl-terminal hydrolase 11 OS=Homo sapiens OX=9606 GN=USP11 PE=1 SV=3 4.37 3578.2 - 1.31E+06 - - - 4.8191 - 2.569 0.475 - 597.7 1 2 0 0.0058 10 0 0 0 1.43E+07 1.96E+06 - - - 5.1812 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.18753.18753.2 0.00511 22-Nov K.GGIVGMTLPIAR.D "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 1183.6747 1.45 60186 18753 2 1183.679541 592.8446 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 9.75 3578.5 - 930186 - - - 4.078 - 1.854 0.455 - 315.6 1 2 0 0.0048 12 0 0 0 9.63E+06 6.64E+06 - - - 4.0245 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.18754.18754.2 0.00173 18-Dec K.TNVALMC[160.03]MLR.E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1207.5876 1.06 60187 18754 2 1207.593204 604.8011 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 7.91 3578.6 - 775103 - - - 4.6779 - 2.33 0.417 - 552 1 2 0 0.0056 10 0 0 0 3.05E+06 2.87E+06 - - - 4.4803 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.18759.18759.2 0.00529 16-Aug R.LFENYIELK.A sp|Q96KP1|EXOC2_HUMAN 1 1167.6176 0.86 60192 18759 2 1167.62233 584.8161 Exocyst complex component 2 OS=Homo sapiens OX=9606 GN=EXOC2 PE=1 SV=1 4.53 3579.3 - 410481 - - - 4.0715 - 1.74 0.288 - 157.1 1 2 0 0.0048 9 0 0 0 1.90E+06 2.21E+06 - - - 2.7691 1 230117_WJC_METTL3_WT_vs_EV_F07.18760.18760.2 2.10E-08 17/30 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 15.59 60193 18760 2 1696.907379 849.4585 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3579.4 - 234414 - - - 2.9607 - 3.179 0.578 - 901.2 1 2 0 0.005 16 0 0 0 3.08E+07 1.98E+06 - - - 6.152 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18764.18764.3 1.32E-11 19/56 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 1.57 60196 18764 3 1458.765863 487.2598 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3579.9 - 5.01E+06 - - - 5.7624 - 3.346 0.51 - 550.9 1 2 0 0.0084 15 0 0 0 1.99E+07 1.27E+07 - - - 7.3752 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.18766.18766.2 0.0212 14-Sep R.EALAFIIR.S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 931.5491 1.03 60198 18766 2 931.55327 466.7818 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3580.1 - 2.68E+06 - - - 4.4743 - 1.819 0.304 - 340.1 1 2 0 0.0042 8 0 0 0 1.20E+07 1.17E+07 - - - 3.0894 1 230117_WJC_METTL3_WT_vs_EV_F07.18767.18767.2 7.34E-08 13/22 K.FGEAIGMGFPVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1251.6322 0.94 60199 18767 2 1251.637386 626.8234 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3580.2 - 2.31E+06 - - - 4.1594 - 2.369 0.586 - 575.1 1 2 0 0.0052 12 0 0 0 8.03E+07 8.57E+07 - - - 5.6369 0.9768 230117_WJC_METTL3_WT_vs_EV_F07.18769.18769.2 0.0223 16-Aug K.WPGDILAYK.E sp|Q9UG63|ABCF2_HUMAN 1 1061.5546 0.82 60201 18769 2 1061.562723 531.7846 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 5.83 3580.4 - 1.37E+06 - - - 7.6689 - 1.807 0.29 - 223.6 1 2 0 0.0081 9 0 0 0 1.44E+07 1.75E+07 - - - 2.8921 0.9935 230117_WJC_METTL3_WT_vs_EV_F07.18770.18770.2 0.0186 18-Jul R.VLGLGLGC[160.03]LR[166.11].L "sp|Q9BRJ7|TIRR_HUMAN,tr|W4VSQ8|W4VSQ8_HUMAN,tr|K7EIN2|K7EIN2_HUMAN,tr|K7ENA3|K7ENA3_HUMAN" 4 1066.6197 2.13 60202 18770 2 1066.624768 534.3171 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3580.5 - 1.03E+06 - - - 4.7936 - 1.595 0.266 - 116.9 1 2 0 0.0051 10 0 0 0 8.80E+06 4.13E+06 - - - 2.3073 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.18773.18773.2 0.00915 20-Nov K.LVFLGLDNAGK.T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1145.6445 1.58 60205 18773 2 1145.649366 573.8295 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3580.9 - 788314 - - - 4.2832 - 2.151 0.367 - 379.7 1 2 0 0.0049 11 0 0 0 2.44E+08 1.55E+08 - - - 3.8222 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18775.18775.2 5.45E-05 16-Sep R.LVLDWDSVR.A "sp|Q68EM7|RHG17_HUMAN,tr|C9IZD3|C9IZD3_HUMAN,tr|I3L4P6|I3L4P6_HUMAN" 3 1101.5819 2.47 60207 18775 2 1101.585031 551.7982 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4.21 3581.1 - 636484 - - - 2.8795 - 1.657 0.514 - 244.5 1 2 0 0.0032 9 0 0 0 1.78E+07 7.20E+06 - - - 4.2974 1 230117_WJC_METTL3_WT_vs_EV_F07.18776.18776.2 4.88E-07 15/22 R.LLYMAIDGVAPR.A sp|Q9H0D6|XRN2_HUMAN 1 1317.7115 1.14 60208 18776 2 1317.716916 659.863 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3581.2 - 547726 - - - 4.1155 - 2.631 0.528 - 1061.1 1 2 0 0.0054 12 0 0 0 2.23E+07 1.96E+07 - - - 5.4844 1 230117_WJC_METTL3_WT_vs_EV_F07.18787.18787.3 2.36E-10 25/60 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 20.98 60217 18787 3 1686.895068 563.3053 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3582.6 - 5.17E+06 - - - 0.5827 - 4.153 0.605 - 812.9 1 2 0 0.001 16 0 0 0 2.60E+07 1.24E+06 - - - 8.9382 1 230117_WJC_METTL3_WT_vs_EV_F07.18788.18788.2 0.00224 20-Dec K.LVFLGLDNAGK[136.11].T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1153.6587 1.58 60218 18788 2 1153.663235 577.8366 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3582.7 - 4.86E+06 - - - 3.9665 - 2.222 0.474 - 485.4 1 2 0 0.0046 11 0 0 0 2.44E+08 1.55E+08 - - - 4.7004 1 230117_WJC_METTL3_WT_vs_EV_F07.18789.18789.2 5.01E-06 13/22 R.LLYMAIDGVAPR[166.11].A sp|Q9H0D6|XRN2_HUMAN 1 1327.7198 1.14 60219 18789 2 1327.725563 664.8672 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3582.8 - 2.01E+06 - - - 4.3684 - 2.352 0.546 - 669.6 1 2 0 0.0058 12 0 0 0 2.23E+07 1.96E+07 - - - 5.3223 0.9912 230117_WJC_METTL3_WT_vs_EV_F07.18793.18793.2 0.867 12-Jun K.LIFYDLR[166.11].G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 948.5308 1.11 60223 18793 2 948.53463 475.2727 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3583.3 - 763817 - - - 4.0136 - 1.317 0.219 - 143.3 1 2 0 0.0038 7 0 0 0 3.05E+07 2.75E+07 - - - 1.5298 0.9703 230117_WJC_METTL3_WT_vs_EV_F07.18794.18794.2 0.315 16-Aug R.GNLLLEQER[166.11].Q "sp|Q6ZSZ5|ARHGI_HUMAN,tr|A0A3B3IPE9|A0A3B3IPE9_HUMAN,tr|A0A590UK10|A0A590UK10_HUMAN,tr|M0QZS0|M0QZS0_HUMAN,tr|A0A087WZG4|A0A087WZG4_HUMAN,tr|A0A804CAZ4|A0A804CAZ4_HUMAN" 6 1080.5803 3.54 60224 18794 2 1080.585453 541.2974 Rho guanine nucleotide exchange factor 18 OS=Homo sapiens OX=9606 GN=ARHGEF18 PE=1 SV=4 4.53 3583.4 - 745492 - - - 4.7752 - 1.656 0.063 - 242 1 2 0 0.0052 9 0 0 0 1.65E+07 4.67E+06 - - - 0.964 0.9901 230117_WJC_METTL3_WT_vs_EV_F07.18795.18795.2 0.29 12-Jul R.VLVWDLR[166.11].N "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 909.5312 1.87 60225 18795 2 909.53487 455.7729 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.81 3583.5 - 720840 - - - 4.0812 - 1.45 0.169 - 249.2 1 2 0 0.0037 7 0 0 0 3.74E+07 2.00E+07 - - - 1.4654 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.18797.18797.2 0.645 16-Aug R.ALLLSTYIK.F "sp|O94973|AP2A2_HUMAN,sp|O95782|AP2A1_HUMAN,tr|A0A0G2JS82|A0A0G2JS82_HUMAN,tr|A0A0G2JQM1|A0A0G2JQM1_HUMAN" 4 1020.6219 0.99 60227 18797 2 1020.623121 511.3182 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 8.63 3583.8 - 573591 - - - 1.164 - 1.775 0.207 - 168.1 3 2 0 0.0012 9 0 0 0 4.02E+06 4.06E+06 - - - 2.0164 1 230117_WJC_METTL3_WT_vs_EV_F07.18799.18799.2 0.00173 13/22 R.IGFDVVTLSGTR[166.11].G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1273.6906 0.97 60229 18799 2 1273.694749 637.8526 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.84 3584.1 - 431756 - - - 3.2794 - 2.562 0.443 - 536 1 2 0 0.0042 12 0 0 0 3.68E+06 3.81E+06 - - - 4.7871 0.9655 230117_WJC_METTL3_WT_vs_EV_F07.18801.18801.2 0.917 12-Jun R.NAFDLFK[136.11].L "sp|Q99549|MPP8_HUMAN,tr|A0A0A0MT47|A0A0A0MT47_HUMAN" 2 861.4476 0.95 60231 18801 2 861.450487 431.7311 M-phase phosphoprotein 8 OS=Homo sapiens OX=9606 GN=MPHOSPH8 PE=1 SV=2 5.84 3584.3 - 352567 - - - 3.3467 - 1.285 0.046 - 125.4 1 2 0 0.0029 7 0 0 0 2.36E+06 2.48E+06 - - - 0.1744 1 230117_WJC_METTL3_WT_vs_EV_F07.18802.18802.2 3.60E-05 22-Nov R.GIYTGLSAGLLR.Q "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 1219.6925 0.34 60232 18802 2 1219.697909 610.8535 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 8.75 3584.4 - 334460 - - - 4.4577 - 1.936 0.534 - 254.6 1 2 0 0.0054 12 0 0 0 5.48E+06 1.61E+07 - - - 4.7216 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18803.18803.2 2.63E-05 22-Sep R.VIQEGLEGLVLK.D sp|P49916|DNLI3_HUMAN 1 1296.7653 3.1 60233 18803 2 1296.768686 649.3899 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 4.53 3584.6 - 298716 - - - 2.6088 - 1.863 0.477 - 224.5 1 2 0 0.0034 12 0 0 0 1.33E+06 4.30E+05 - - - 4.2001 1 230117_WJC_METTL3_WT_vs_EV_F07.18804.18804.2 0.000126 20-Nov R.VYPQAVYFPIR.T "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1351.7289 1.5 60234 18804 2 1351.733452 676.8717 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.56 3584.7 - 287237 - - - 3.3986 - 2.258 0.453 - 546.6 1 2 0 0.0046 11 0 0 0 1.93E+06 1.29E+06 - - - 4.5888 0.9959 230117_WJC_METTL3_WT_vs_EV_F07.18807.18807.2 0.0104 20-Oct K.NPLIINSIIDK[136.11].A "sp|Q9UNQ2|DIM1_HUMAN,tr|A0A494C0G7|A0A494C0G7_HUMAN,tr|B4DRY2|B4DRY2_HUMAN,tr|A0A7P0T8X7|A0A7P0T8X7_HUMAN,tr|A0A0C4DGB1|A0A0C4DGB1_HUMAN,tr|A0A7P0T967|A0A7P0T967_HUMAN,tr|A0A7P0T9J1|A0A7P0T9J1_HUMAN,tr|A0A7P0Z4I0|A0A7P0Z4I0_HUMAN,tr|A0A7P0T9Y7|A0A7P0T9Y7_HUMAN,tr|D6RCL3|D6RCL3_HUMAN" 10 1246.7376 1.07 60236 18807 2 1246.743469 624.3761 Probable dimethyladenosine transferase OS=Homo sapiens OX=9606 GN=DIMT1 PE=1 SV=1 5.84 3585.1 - 494806 - - - 4.677 - 1.714 0.302 - 268.8 1 2 0 0.0058 11 0 0 0 4.75E+06 4.43E+06 - - - 2.7274 0.999 230117_WJC_METTL3_WT_vs_EV_F07.18809.18809.2 0.00459 14-Jul R.ILFFNTPK.K "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 978.5539 1.5 60238 18809 2 978.556531 490.2842 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 8.75 3585.2 - 4.17E+06 - - - 2.7357 - 1.501 0.361 - 136.3 1 2 0 0.0027 8 0 0 0 4.51E+07 3.01E+07 - - - 2.9314 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.18810.18810.2 0.179 12-Jul K.LIFYDLR.G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 938.5226 1.11 60239 18810 2 938.52534 470.2686 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3585.3 - 3.70E+06 - - - 2.9696 - 1.442 0.344 - 192.9 1 2 0 0.0028 7 0 0 0 3.05E+07 2.75E+07 - - - 2.7407 0.9908 230117_WJC_METTL3_WT_vs_EV_F07.18813.18813.2 0.00664 14-Aug R.QAFYFALR.D "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1014.5287 1.29 60242 18813 2 1014.535212 508.2716 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.75 3585.6 - 1.13E+06 - - - 6.4178 - 1.642 0.36 - 214.4 1 2 0 0.0065 8 0 0 0 4.66E+06 3.61E+06 - - - 3.1936 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.18814.18814.2 0.000157 20-Aug R.VLPSITTEILK.S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1212.7329 1.45 60243 18814 2 1212.73593 607.3737 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 3585.8 - 1.11E+06 - - - 2.4655 - 1.789 0.211 - 186.1 2 2 0 0.003 11 0 0 0 2.62E+08 1.80E+08 - - - 2.0376 0.9921 230117_WJC_METTL3_WT_vs_EV_F07.18817.18817.2 0.186 12-Jul R.TLIGFLR.S "sp|O15116|LSM1_HUMAN,tr|E5RH18|E5RH18_HUMAN,tr|E5RJ47|E5RJ47_HUMAN" 3 818.5014 1.48 60246 18817 2 818.503624 410.258 U6 snRNA-associated Sm-like protein LSm1 OS=Homo sapiens OX=9606 GN=LSM1 PE=1 SV=1 9.41 3586.1 - 520757 - - - 2.6878 - 1.332 0.135 - 193.4 1 2 0 0.0022 7 0 0 0 8.45E+06 5.70E+06 - - - 0.9458 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.18819.18819.2 0.00214 18-Sep R.YYAFDEAFVR.E "sp|O43427|FIBP_HUMAN,tr|E9PSD3|E9PSD3_HUMAN,tr|E9PJW6|E9PJW6_HUMAN" 3 1279.5873 5.95 60248 18819 2 1279.585673 640.8009 Acidic fibroblast growth factor intracellular-binding protein OS=Homo sapiens OX=9606 GN=FIBP PE=1 SV=3 4.37 3586.4 - 372231 - - - -1.302 - 1.438 0.345 - 189.3 1 2 0 -0.0017 10 0 0 0 1.64E+06 2.76E+05 - - - 2.6026 0.892 230117_WJC_METTL3_WT_vs_EV_F07.18820.18820.2 0.00194 20-Sep K.IFAVSGLISDR.E sp|Q5VTB9|RN220_HUMAN 1 1176.6503 11.17 60249 18820 2 1176.640101 589.3324 E3 ubiquitin-protein ligase RNF220 OS=Homo sapiens OX=9606 GN=RNF220 PE=1 SV=1 5.84 3586.5 - 334939 - - - -8.6449 - 1.646 0.356 - 128.1 1 2 0 -0.0102 11 0 0 0 1.81E+06 1.62E+05 - - - 3.0154 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18821.18821.2 0.00728 16-Oct R.VLAINILGR.F sp|O43747|AP1G1_HUMAN 1 967.6179 0.32 60250 18821 2 967.620197 484.8162 AP-1 complex subunit gamma-1 OS=Homo sapiens OX=9606 GN=AP1G1 PE=1 SV=5 9.72 3586.7 - 317191 - - - 2.4245 - 1.967 0.306 - 314.2 1 2 0 0.0023 9 0 0 0 3.11E+06 9.60E+06 - - - 3.2576 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18828.18828.2 0.00202 18-Aug K.ELLTSFGPLK[136.11].A "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1111.6369 1.66 60255 18828 2 1111.639355 556.8257 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6.1 3587.6 - 2.61E+06 - - - 2.2435 - 1.893 0.355 - 200.2 1 2 0 0.0025 10 0 0 0 4.00E+07 2.41E+07 - - - 3.4436 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.18829.18829.2 0.0114 14-Aug R.ILFFNTPK[136.11].K "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 986.5681 1.64 60256 18829 2 986.570201 494.2913 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 8.75 3587.6 - 3.00E+06 - - - 2.1762 - 1.603 0.349 - 169.9 1 2 0 0.0021 8 0 0 0 4.43E+07 2.70E+07 - - - 3.0412 1 230117_WJC_METTL3_WT_vs_EV_F07.18830.18830.2 1.87E-05 20-Oct R.VLPSITTEILK[136.11].S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1220.7471 1.45 60257 18830 2 1220.74922 611.3808 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 3587.7 - 1.77E+06 - - - 1.7039 - 1.988 0.5 - 351.7 1 2 0 0.0021 11 0 0 0 2.62E+08 1.80E+08 - - - 4.5922 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18833.18833.2 0.00101 14-Oct K.C[160.03]QLLFALK.V "sp|Q9BRJ7|TIRR_HUMAN,tr|K7EIN2|K7EIN2_HUMAN" 2 991.5525 0.92 60260 18833 2 991.551722 496.7835 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3588 - 648955 - - - -0.7584 - 2.036 0.455 - 375.1 1 2 0 -0.0008 8 0 0 0 7.73E+06 8.45E+06 - - - 4.5457 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.18836.18836.2 0.0569 16-Oct K.ALLSALELK.K sp|P49454|CENPF_HUMAN 1 956.5906 1.13 60263 18836 2 956.591706 479.3026 Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3 6.05 3588.4 - 482488 - - - 1.1217 - 1.772 0.22 - 231.2 1 2 0 0.0011 9 0 0 0 2.69E+06 2.37E+06 - - - 2.3207 0.9918 230117_WJC_METTL3_WT_vs_EV_F07.18837.18837.2 0.464 12-Jul R.FPFEIVK.M "sp|Q9UQ16|DYN3_HUMAN,sp|Q05193|DYN1_HUMAN,sp|P50570|DYN2_HUMAN,tr|A0A0D9SFB1|A0A0D9SFB1_HUMAN,tr|A0A1B0GU67|A0A1B0GU67_HUMAN,tr|A0A0D9SFE4|A0A0D9SFE4_HUMAN,tr|H7C5U0|H7C5U0_HUMAN,tr|E5RIK2|E5RIK2_HUMAN,tr|K7EMQ3|K7EMQ3_HUMAN,tr|A0A0U1RQP1|A0A0U1RQP1_HUMAN,tr|E5RHK8|E5RHK8_HUMAN" 11 878.4902 0.47 60264 18837 2 878.49216 440.2524 Dynamin-3 OS=Homo sapiens OX=9606 GN=DNM3 PE=1 SV=4 6 3588.5 - 460542 - - - 2.2413 - 1.276 0.146 - 149.6 2 2 0 0.002 7 0 0 0 3.53E+06 7.55E+06 - - - 0.7565 1 230117_WJC_METTL3_WT_vs_EV_F07.18840.18840.2 9.85E-05 16-Oct R.FEALNLSFK[136.11].N "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 12 1075.5793 1.86 60267 18840 2 1075.583419 538.7969 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 6 3588.9 - 339732 - - - 3.7859 - 2.087 0.474 - 255.6 1 2 0 0.0041 9 0 0 0 4.66E+07 2.51E+07 - - - 4.6692 0.999 230117_WJC_METTL3_WT_vs_EV_F07.18841.18841.2 0.0171 18-Aug R.LWTPPEDYRL.- "sp|Q9BYD1|RM13_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 2 1288.6452 1.72 60268 18841 2 1288.645279 645.3299 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.37 3589 - 296128 - - - 0.0706 - 1.727 0.295 - 241.5 1 2 0 0.0001 10 0 0 0 2.97E+06 1.73E+06 - - - 2.745 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.18848.18848.2 0.00209 18-Jul K.ELLTSFGPLK.A "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1103.6227 1.66 60273 18848 2 1103.627607 552.8186 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6.1 3589.9 - 9.16E+06 - - - 4.4816 - 1.634 0.376 - 130.9 1 2 0 0.0049 10 0 0 0 4.00E+07 2.41E+07 - - - 3.1872 0.989 230117_WJC_METTL3_WT_vs_EV_F07.18849.18849.2 0.000742 14-Sep R.FLIQNVLR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1001.6022 1.44 60274 18849 2 1001.609131 501.8084 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.75 3590 - 5.78E+06 - - - 6.9189 - 1.995 0.306 - 365.6 1 2 0 0.0069 8 0 0 0 5.79E+07 4.03E+07 - - - 3.3819 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.18850.18850.2 0.0686 16-Oct R.FEALNLSFK.N "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 12 1067.5651 1.4 60275 18850 2 1067.568565 534.7898 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 6 3590 - 6.44E+06 - - - 3.2017 - 1.754 0.29 - 267.6 1 2 0 0.0034 9 0 0 0 4.66E+07 3.33E+07 - - - 2.8075 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.18851.18851.2 0.348 14-Jul R.FLIQNVLR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1011.6105 1.44 60276 18851 2 1011.613148 506.8125 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.75 3590.1 - 4.73E+06 - - - 2.6463 - 1.491 0.281 - 193.6 1 2 0 0.0027 8 0 0 0 5.79E+07 4.03E+07 - - - 2.3203 0.9959 230117_WJC_METTL3_WT_vs_EV_F07.18855.18855.2 0.198 18-Aug K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.07 60280 18855 2 1086.646999 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3590.6 - 1.13E+06 - - - 3.0074 - 1.606 0.17 - 148.5 1 2 0 0.0033 10 0 0 0 4.57E+06 4.27E+06 - - - 1.618 1 230117_WJC_METTL3_WT_vs_EV_F07.18857.18857.2 9.64E-06 20-Nov K.FLEMC[160.03]NDLLAR.V "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1380.653 7.93 60282 18857 2 1380.655884 691.3338 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.37 3590.8 - 991650 - - - 2.0947 - 2.327 0.497 - 439.3 1 2 0 0.0029 11 0 0 0 1.20E+07 1.51E+06 - - - 4.9957 1 230117_WJC_METTL3_WT_vs_EV_F07.18860.18860.2 8.74E-05 26-Dec K.YILVTGGVISGIGK.G "sp|P17812|PYRG1_HUMAN,sp|Q9NRF8|PYRG2_HUMAN,tr|A0A3B3ITH9|A0A3B3ITH9_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 7 1375.8075 1.88 60285 18860 2 1375.810547 688.911 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 8.59 3591.2 - 440708 - - - 2.2132 - 2.362 0.475 - 415.7 1 2 0 0.003 14 0 0 0 2.15E+06 1.14E+06 - - - 4.7053 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18862.18862.2 0.0135 24-Sep K.ILTPLVSLDTPGK.A "sp|Q9HC38|GLOD4_HUMAN,tr|I3L1I0|I3L1I0_HUMAN,tr|F6TLX2|F6TLX2_HUMAN" 3 1352.7915 1.25 60287 18862 2 1352.793008 677.403 Glyoxalase domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GLOD4 PE=1 SV=1 5.84 3591.5 - 307122 - - - 1.1014 - 1.588 0.361 - 200.6 1 2 0 0.0015 13 0 0 0 9.71E+05 7.79E+05 - - - 2.8938 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18867.18867.2 0.000132 16-Oct R.SPTWFGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1059.5502 0.97 60291 18867 2 1059.552218 530.7824 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3592.1 - 2.15E+06 - - - 1.9376 - 2.072 0.442 - 557.1 1 2 0 0.0021 9 0 0 0 1.59E+08 1.63E+08 - - - 4.4126 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.18871.18871.2 0.00016 20-Oct K.YLLDSC[160.03]APLLR[166.11].Y sp|Q92616|GCN1_HUMAN 1 1329.699 0.96 60295 18871 2 1329.697346 665.8568 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.83 3592.4 - 442166 - - - -1.2649 - 1.821 0.503 - 339.9 1 2 0 -0.0017 11 0 0 0 4.05E+06 4.23E+06 - - - 4.3771 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.18874.18874.2 0.42 16-Jul R.LQYLIDLGR.V "sp|Q9P015|RM15_HUMAN,tr|E5RHF4|E5RHF4_HUMAN,tr|E5RIZ4|E5RIZ4_HUMAN" 3 1089.6182 1.16 60298 18874 2 1089.620849 545.8164 "39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1" 5.84 3592.6 - 299795 - - - 2.3898 - 1.801 0.3 - 121.3 1 2 0 0.0026 9 0 0 0 1.03E+07 8.86E+06 - - - 2.9581 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.18877.18877.3 0.000179 14/40 R.ILVTLLHTLER[166.11].M sp|Q9BWD1|THIC_HUMAN 1 1316.8055 1.24 60301 18877 3 1316.806772 439.9425 "Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2" 6.75 3593 - 221852 - - - 0.9341 - 2.174 0.395 - 225.2 1 2 0 0.0012 11 0 0 0 7.05E+06 5.69E+06 - - - 5.1496 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.18880.18880.2 0.351 12-May R.VLVWDLR.N "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 899.5229 1.67 60303 18880 2 899.524019 450.7687 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.81 3593.4 - 535757 - - - 1.2573 - 1.309 0.189 - 131.5 1 2 0 0.0011 7 0 0 0 3.75E+07 2.25E+07 - - - 1.2898 1 230117_WJC_METTL3_WT_vs_EV_F07.18883.18883.2 6.56E-05 18-Nov R.FEELC[160.03]SDLFR.S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1314.5914 14.22 60306 18883 2 1314.596593 658.303 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.14 3593.7 - 834829 - - - 3.9214 - 2.141 0.537 - 442.8 1 2 0 0.0052 10 0 0 0 4.17E+06 2.94E+05 - - - 5.1306 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.18884.18884.3 0.000618 Dec-40 R.ILVTLLHTLER.M sp|Q9BWD1|THIC_HUMAN 1 1306.7973 1.24 60307 18884 3 1306.802827 436.6064 "Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2" 6.75 3593.9 - 487288 - - - 4.2509 - 2.388 0.447 - 254.9 1 2 0 0.0056 11 0 0 0 7.05E+06 5.69E+06 - - - 5.9949 1 230117_WJC_METTL3_WT_vs_EV_F07.18885.18885.2 0.000684 18-Nov K.LYGEFADPFK.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1185.5706 1.91 60308 18885 2 1185.577391 593.7926 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3594 - 468476 - - - 5.7061 - 2.037 0.52 - 354.3 1 2 0 0.0068 10 0 0 0 9.45E+06 4.95E+06 - - - 4.8655 1 230117_WJC_METTL3_WT_vs_EV_F07.18888.18888.2 9.36E-07 15/26 R.ALMGSPQLVAAVVR.T "sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9J826|C9J826_HUMAN" 5 1410.8017 44.54 60311 18888 2 1410.805949 706.4081 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 9.79 3594.4 - 430404 - - - 3.0082 - 2.793 0.515 - 681 1 2 0 0.0042 14 0 0 0 1.02E+07 2.30E+05 - - - 5.421 0.9636 230117_WJC_METTL3_WT_vs_EV_F07.18889.18889.2 0.969 12-Jul R.NLPFLIK[136.11].K sp|Q86TB9|PATL1_HUMAN 1 851.536 1.06 60312 18889 2 851.539455 426.7753 Protein PAT1 homolog 1 OS=Homo sapiens OX=9606 GN=PATL1 PE=1 SV=2 8.75 3594.5 - 427938 - - - 4.028 - 1.216 0.106 - 166.2 1 2 0 0.0034 7 0 0 0 4.71E+06 4.45E+06 - - - 0.4425 0.9959 230117_WJC_METTL3_WT_vs_EV_F07.18891.18891.2 0.00461 14-Aug R.TSFLLNLR[166.11].R "sp|O00159|MYO1C_HUMAN,tr|F5H6E2|F5H6E2_HUMAN" 2 972.5632 0.26 60314 18891 2 972.568218 487.2889 Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4 9.41 3594.8 - 169707 - - - 5.174 - 1.763 0.325 - 148.5 1 2 0 0.005 8 0 0 0 1.08E+06 4.12E+06 - - - 3.15 0.9958 230117_WJC_METTL3_WT_vs_EV_F07.18894.18894.2 0.00722 24-Oct R.LIEETISIAMATK[136.11].E "sp|O95249|GOSR1_HUMAN,tr|E9PCW1|E9PCW1_HUMAN,tr|G5E9T8|G5E9T8_HUMAN" 3 1426.7833 0.63 60317 18894 2 1426.791554 714.3989 Golgi SNAP receptor complex member 1 OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 4.53 3595.2 - 102884 - - - 5.8075 - 1.984 0.406 - 229.3 1 2 0 0.0083 13 0 0 0 4.76E+05 7.52E+05 - - - 3.7955 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.18904.18904.2 0.0174 14-Aug K.FEFLGINR.Q sp|Q8N3X1|FNBP4_HUMAN 1 994.5236 1.49 60325 18904 2 994.522761 498.2691 Formin-binding protein 4 OS=Homo sapiens OX=9606 GN=FNBP4 PE=1 SV=3 6 3596.3 - 493207 - - - -0.8597 - 1.709 0.285 - 191.9 1 2 0 -0.0009 8 0 0 0 4.94E+06 3.31E+06 - - - 2.762 0.9892 230117_WJC_METTL3_WT_vs_EV_F07.18907.18907.2 0.269 12-Jul R.WFEAFVK.R "sp|Q99543|DNJC2_HUMAN,tr|F2Z3H0|F2Z3H0_HUMAN,tr|H7C3L7|H7C3L7_HUMAN,tr|F2Z3N9|F2Z3N9_HUMAN" 4 925.4698 0.37 60328 18907 2 925.47165 463.7422 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 6 3596.6 - 353049 - - - 2.0098 - 1.257 0.099 - 134.8 1 2 0 0.0019 7 0 0 0 7.74E+06 2.10E+07 - - - 0.4964 1 230117_WJC_METTL3_WT_vs_EV_F07.18913.18913.2 3.57E-08 14/22 K.FGEAIGMGFPVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1259.6464 1.06 60333 18913 2 1259.64833 630.8305 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3597.3 - 3.57E+06 - - - 1.5481 - 2.591 0.54 - 622.3 1 2 0 0.0019 12 0 0 0 3.81E+07 3.58E+07 - - - 5.5338 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.18914.18914.2 0.068 18-Aug R.YDLGGLVMVK.D sp|Q15274|NADC_HUMAN 1 1093.5842 0.43 60334 18914 2 1093.587876 547.7994 Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Homo sapiens OX=9606 GN=QPRT PE=1 SV=3 5.83 3597.4 - 1.32E+06 - - - 3.3916 - 1.648 0.335 - 167.7 1 2 0 0.0037 10 0 0 0 2.34E+07 5.44E+07 - - - 2.9086 0.9969 230117_WJC_METTL3_WT_vs_EV_F07.18915.18915.2 0.0231 18-Sep K.LYGEFADPFK[136.11].L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1193.5848 1.91 60335 18915 2 1193.588696 597.7997 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3597.5 - 624867 - - - 3.2423 - 1.362 0.284 - 193.7 1 2 0 0.0039 10 0 0 0 9.45E+06 4.95E+06 - - - 1.9998 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.18917.18917.2 0.0173 16-Jun K.LFTTMELMR[166.11].W sp|O00232|PSD12_HUMAN 1 1150.5754 1.43 60337 18917 2 1150.577767 576.295 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 6 3597.8 - 416950 - - - 2.0511 - 1.446 0.239 - 76.8 1 2 0 0.0024 9 0 0 0 5.74E+06 4.01E+06 - - - 1.8725 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.18923.18923.2 0.25 16-Nov K.ELIEELIAK[136.11].S "sp|P78316|NOP14_HUMAN,tr|E9PFK5|E9PFK5_HUMAN" 2 1064.6209 0.65 60341 18923 2 1064.624412 533.3177 Nucleolar protein 14 OS=Homo sapiens OX=9606 GN=NOP14 PE=1 SV=3 4.25 3598.5 - 1.30E+06 - - - 3.3204 - 1.981 0.27 - 377.6 1 2 0 0.0035 9 0 0 0 1.70E+07 2.62E+07 - - - 3.0118 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18927.18927.2 0.00397 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 21.98 60345 18927 2 1006.571127 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3598.9 - 913178 - - - 1.221 - 1.597 0.409 - 235.7 1 2 0 0.0012 9 0 0 0 6.44E+06 2.93E+05 - - - 3.4158 0.9941 230117_WJC_METTL3_WT_vs_EV_F07.18928.18928.2 0.055 18-Jul R.FPPVVFYTPK.E "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1193.6485 1.61 60346 18928 2 1193.650201 597.8315 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3598.9 - 775858 - - - 1.4401 - 1.147 0.194 - 104.8 1 2 0 0.0017 10 0 0 0 3.89E+06 2.42E+06 - - - 0.8562 0.9367 230117_WJC_METTL3_WT_vs_EV_F07.18932.18932.2 11.1 16-May K.MSIYQAMWK[136.11].G "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 10 1164.5551 125.94 60350 18932 2 1164.555505 583.2848 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 8.34 3599.5 - 267717 - - - 0.3289 - 0.877 0.117 - 45.4 2 2 0 0.0004 9 0 0 0 1.20E+08 9.51E+05 - - - -0.6091 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18936.18936.2 0.0551 18-Oct K.AIAINTFLPK[136.11].N sp|Q92615|LAR4B_HUMAN 1 1094.6579 1.18 60353 18936 2 1094.659017 548.3362 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3599.9 - 5.89E+06 - - - 0.9921 - 1.863 0.317 - 274.7 2 2 0 0.0011 10 0 0 0 2.71E+07 2.30E+07 - - - 2.9843 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18938.18938.2 0.000435 16-Aug R.YLTVAAVFR[166.11].G "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 5 1048.5945 2.97 60354 18938 2 1048.595283 525.3045 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3600.1 - 4.86E+06 - - - 0.7601 - 1.849 0.369 - 197.2 1 2 0 0.0008 9 0 0 0 1.30E+09 4.39E+08 - - - 3.5444 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.18941.18941.2 0.00231 18-Jun R.IPDEIIDMVK.E "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1171.6159 2.11 60357 18941 2 1171.615414 586.8152 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 4.03 3600.3 - 5.88E+06 - - - -0.3824 - 1.253 0.403 - 114 1 2 0 -0.0004 10 0 0 0 2.95E+07 1.39E+07 - - - 2.647 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.18944.18944.2 0.158 14-Aug K.TVALWDLR.N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 972.5393 2.01 60360 18944 2 972.540035 487.2769 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3600.5 - 2.29E+06 - - - 0.7907 - 1.416 0.336 - 252.5 1 2 0 0.0008 8 0 0 0 9.73E+08 4.83E+08 - - - 2.5715 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18945.18945.2 1.22E-05 13/20 K.IGDFGLVTSLK.N "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 3 1148.6441 365.74 60361 18945 2 1148.644976 575.3293 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 5.84 3600.5 - 1.89E+06 - - - 0.7409 - 2.564 0.268 - 408.6 1 2 0 0.0009 11 0 0 0 4.01E+07 1.10E+05 - - - 3.5673 0.9958 230117_WJC_METTL3_WT_vs_EV_F07.18947.18947.2 0.168 16-Oct R.ALVAVLLSR.T sp|Q92616|GCN1_HUMAN 1 940.607 1.1 60363 18947 2 940.606694 471.3108 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.79 3600.7 - 1.51E+06 - - - -0.2743 - 1.766 0.117 - 324.3 1 2 0 -0.0003 9 0 0 0 7.49E+06 6.79E+06 - - - 1.5504 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.18950.18950.2 9.83E-05 22-Oct K.IIATVLMTEDIK[136.11].L "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 1353.7669 0.14 60366 18950 2 1353.765767 677.8907 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 3601 - 700006 - - - -0.8288 - 2.147 0.439 - 243.2 1 2 0 -0.0011 12 0 0 0 2.91E+05 2.04E+06 - - - 4.2935 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.18953.18953.2 0.606 20-Aug R.VEILPSYIPVR[166.11].V "sp|Q9UGJ1|GCP4_HUMAN,tr|H3BPU4|H3BPU4_HUMAN" 2 1294.7524 1.23 60369 18953 2 1294.754278 648.3835 Gamma-tubulin complex component 4 OS=Homo sapiens OX=9606 GN=TUBGCP4 PE=1 SV=1 5.97 3601.4 - 609197 - - - 1.4165 - 1.511 0.175 - 192.8 1 2 0 0.0018 11 0 0 0 2.07E+06 1.69E+06 - - - 1.4496 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18954.18954.2 0.000252 20-Oct K.FLC[160.03]YLSQAGFR[166.11].V sp|Q7Z2T5|TRM1L_HUMAN 1 1370.6681 1.71 60370 18954 2 1370.671654 686.3413 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 8.22 3601.5 - 593872 - - - 2.6206 - 1.644 0.46 - 354.2 1 2 0 0.0036 11 0 0 0 2.80E+06 1.63E+06 - - - 3.7823 0.9838 230117_WJC_METTL3_WT_vs_EV_F07.18957.18957.2 0.633 12-Jul R.YILDYLR[166.11].D "sp|Q96CX2|KCD12_HUMAN,sp|Q68DU8|KCD16_HUMAN" 2 964.5257 1.28 60372 18957 2 964.525792 483.2701 BTB\POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1 5.83 3601.9 - 664709 - - - 0.056 - 1.388 0.041 - 199.5 1 2 0 0.0001 7 0 0 0 5.84E+06 4.57E+06 - - - 0.3827 1 230117_WJC_METTL3_WT_vs_EV_F07.18959.18959.2 0.000274 18-Nov R.ILVATNLFGR.G "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 6 1102.6499 1.4 60373 18959 2 1102.649099 552.3322 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 9.75 3602.1 - 2.00E+06 - - - -0.7074 - 2.314 0.455 - 430 1 2 0 -0.0008 10 0 0 0 6.29E+08 4.50E+08 - - - 4.7432 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.18960.18960.2 0.0158 14-Aug K.TVALWDLR[166.11].N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 982.5475 2.01 60374 18960 2 982.547279 492.281 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3602.2 - 3.36E+06 - - - -0.2616 - 1.733 0.374 - 204.8 1 2 0 -0.0003 8 0 0 0 9.73E+08 4.83E+08 - - - 3.4616 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.18970.18970.2 0.00374 12-Sep K.WMGIAFR.L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 879.4425 1.32 60384 18970 2 879.441404 440.7285 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.75 3603.4 - 549072 - - - -1.2792 - 1.468 0.273 - 389.3 1 2 0 -0.0011 7 0 0 0 3.85E+07 2.93E+07 - - - 2.2734 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.18979.18979.2 0.00309 20-Oct K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 0.91 60392 18979 2 1197.720744 599.8679 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3604.3 - 4.04E+06 - - - -0.4308 - 2.289 0.414 - 451.5 1 2 0 -0.0005 11 0 0 0 1.59E+09 1.74E+09 - - - 4.3389 1 230117_WJC_METTL3_WT_vs_EV_F07.18980.18980.2 1.63E-05 20-Sep K.VANVSLLALYK.G sp|P62266|RS23_HUMAN 1 1189.7071 0.91 60393 18980 2 1189.706031 595.8608 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3604.3 - 2.80E+06 - - - -0.8649 - 1.951 0.544 - 380.7 1 2 0 -0.001 11 0 0 0 1.59E+09 1.74E+09 - - - 4.8667 0.9914 230117_WJC_METTL3_WT_vs_EV_F07.18981.18981.2 0.0696 12-Jul K.WMGIAFR[166.11].L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 889.4508 1.31 60394 18981 2 889.450366 445.7327 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.75 3604.4 - 1.20E+06 - - - -0.4868 - 1.126 0.224 - 224.2 1 2 0 -0.0004 7 0 0 0 3.85E+07 2.93E+07 - - - 1.0713 0.856 230117_WJC_METTL3_WT_vs_EV_F07.18982.18982.2 0.00532 12-Aug L.SGFLVWR[166.11].R "sp|Q9NP84|TNR12_HUMAN,sp|Q96T88|UHRF1_HUMAN,tr|I3L1J9|I3L1J9_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 6 873.4736 1.35 60395 18982 2 873.472137 437.7441 Tumor necrosis factor receptor superfamily member 12A OS=Homo sapiens OX=9606 GN=TNFRSF12A PE=1 SV=1 9.47 3604.5 - 737408 - - - -1.7242 - 1.687 0.346 - 254.3 1 1 0 -0.0015 7 0 0 0 2.20E+07 1.63E+07 - - - 3.2531 0.9912 230117_WJC_METTL3_WT_vs_EV_F07.18983.18983.2 0.157 12-Jul R.FVLNLIK[136.11].L sp|Q8TDN6|BRX1_HUMAN 1 853.5517 0.74 60396 18983 2 853.550577 427.7831 Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2 8.75 3604.6 - 688740 - - - -1.2864 - 1.442 0.17 - 146.4 1 2 0 -0.0011 7 0 0 0 7.67E+07 1.04E+08 - - - 1.4561 0.9637 230117_WJC_METTL3_WT_vs_EV_F07.18987.18987.2 0.159 12-May R.GLFDSFR.R "sp|Q96IK1|BOD1_HUMAN,sp|Q8IYS8|BD1L2_HUMAN,tr|C9JNZ5|C9JNZ5_HUMAN" 3 840.413 2.66 60398 18987 2 840.411328 421.2138 Biorientation of chromosomes in cell division protein 1 OS=Homo sapiens OX=9606 GN=BOD1 PE=1 SV=2 5.84 3605.1 - 452258 - - - -1.9931 - 1.205 0.144 - 103.5 1 2 0 -0.0017 7 0 0 0 1.25E+07 4.71E+06 - - - 0.6949 0.9826 230117_WJC_METTL3_WT_vs_EV_F07.18992.18992.2 0.192 12-Jul R.FVLNLIK.L sp|Q8TDN6|BRX1_HUMAN 1 845.5375 0.74 60401 18992 2 845.53552 423.776 Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2 8.75 3605.8 - 2.20E+06 - - - -2.3121 - 1.434 0.169 - 147.6 1 2 0 -0.002 7 0 0 0 7.67E+07 1.04E+08 - - - 1.4308 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.18993.18993.2 0.0302 16-Sep R.LDALLAELR[166.11].A sp|Q96L58|B3GT6_HUMAN 1 1022.6 0.98 60402 18993 2 1022.600875 512.3073 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 4.37 3605.9 - 2.03E+06 - - - 0.8889 - 2.289 0.211 - 298.5 1 2 0 0.0009 9 0 0 0 3.25E+07 3.32E+07 - - - 2.9949 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.18994.18994.2 0.0157 16-Oct R.LDALLAELR.A sp|Q96L58|B3GT6_HUMAN 1 1012.5917 0.98 60403 18994 2 1012.591513 507.3031 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 4.37 3606 - 1.74E+06 - - - -0.1807 - 2.308 0.178 - 356.2 1 2 0 -0.0002 9 0 0 0 3.25E+07 3.32E+07 - - - 2.7753 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.18997.18997.2 0.00179 14-Aug R.AEWLLAVR[166.11].S sp|Q9NRN7|ADPPT_HUMAN 1 966.5526 2.9 60406 18997 2 966.552225 484.2836 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2 6.05 3606.4 - 676519 - - - -0.4097 - 1.709 0.351 - 290.9 1 2 0 -0.0004 8 0 0 0 5.21E+07 1.79E+07 - - - 3.2496 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.18998.18998.2 0.00118 24-Dec K.AEPLLGAPGELLK.Q sp|P17482|HXB9_HUMAN 1 1306.7497 2.59 60407 18998 2 1306.749805 654.3821 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 3606.5 - 489903 - - - 0.1163 - 2.026 0.485 - 385.5 1 2 0 0.0002 13 0 0 0 2.95E+07 1.14E+07 - - - 4.4353 1 230117_WJC_METTL3_WT_vs_EV_F07.18999.18999.2 8.96E-09 13/24 K.DIPVLVATDVAAR.G "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1338.7507 1.89 60408 18999 2 1338.749096 670.3826 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3606.6 - 425818 - - - -1.2101 - 2.538 0.508 - 580 1 2 0 -0.0016 13 0 0 0 1.15E+07 6.08E+06 - - - 5.183 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.19000.19000.2 0.357 20-Aug K.FLC[160.03]YLSQAGFR.V sp|Q7Z2T5|TRM1L_HUMAN 1 1360.6598 1.93 60409 19000 2 1360.659499 681.3372 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 8.22 3606.8 - 419834 - - - -0.2153 - 1.754 0.383 - 196.2 1 2 0 -0.0003 11 0 0 0 5.95E+06 3.07E+06 - - - 3.3898 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19004.19004.2 0.00667 18-Nov R.FLLQDTVELR.E "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1232.6765 1.75 60411 19004 2 1232.675526 617.3455 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3607.2 - 2.45E+06 - - - -0.7804 - 2.303 0.34 - 532.5 1 2 0 -0.001 10 0 0 0 1.51E+08 8.64E+07 - - - 3.8805 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.19006.19006.2 1.75E-05 18-Sep R.FEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1252.6088 11.03 60413 19006 2 1252.606329 627.3117 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3607.4 - 1.93E+06 - - - -1.9743 - 2 0.475 - 272.8 1 2 0 -0.0025 10 0 0 0 7.57E+08 6.86E+07 - - - 4.4834 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.19009.19009.2 0.0902 12-Jul R.VLFLIPK[136.11].N "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q5JV98|Q5JV98_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|H0Y630|H0Y630_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 13 836.5615 2.06 60416 19009 2 836.560335 419.288 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 8.72 3607.8 - 598227 - - - -1.4069 - 1.473 0.383 - 139.8 1 2 0 -0.0012 7 0 0 0 5.09E+07 2.47E+07 - - - 3.0967 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.19013.19013.2 0.0031 14-Aug R.AEWLLAVR.S sp|Q9NRN7|ADPPT_HUMAN 1 956.5444 2.9 60418 19013 2 956.54408 479.2795 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2 6.05 3608.4 - 4.33E+06 - - - -0.2833 - 1.536 0.343 - 340.1 1 2 0 -0.0003 8 0 0 0 5.21E+07 1.79E+07 - - - 2.8687 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19014.19014.2 9.29E-06 16-Oct R.LDDSLLYLR[166.11].D "sp|P49406|RM19_HUMAN,tr|S4R455|S4R455_HUMAN,tr|S4R3W9|S4R3W9_HUMAN" 3 1116.6054 1.15 60419 19014 2 1116.606034 559.31 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 4.21 3608.4 - 6.82E+06 - - - 0.5275 - 2.136 0.422 - 305.9 1 2 0 0.0006 9 0 0 0 3.87E+07 3.37E+07 - - - 4.3533 0.9611 230117_WJC_METTL3_WT_vs_EV_F07.19015.19015.2 12 12-Jul R.VLFLIPK.N "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q5JV98|Q5JV98_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|H0Y630|H0Y630_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 13 828.5473 2.06 60420 19015 2 828.546367 415.2809 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 8.72 3608.5 - 4.01E+06 - - - -1.1406 - 1.183 0.094 - 215 1 2 0 -0.0009 7 0 0 0 5.09E+07 2.47E+07 - - - 0.2675 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19016.19016.2 0.0147 18-Oct R.FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1262.6171 11.01 60421 19016 2 1262.617328 632.3158 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3608.6 - 1.42E+06 - - - 0.2028 - 2.103 0.38 - 331.7 1 2 0 0.0003 10 0 0 0 7.55E+08 6.86E+07 - - - 3.9226 0.9854 230117_WJC_METTL3_WT_vs_EV_F07.19017.19017.2 0.00105 22-Sep R.SLVPAAELLESR.V "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1283.7085 2.55 60422 19017 2 1283.701828 642.8615 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 3608.6 - 970596 - - - -5.2099 - 1.817 0.409 - 244.3 1 2 0 -0.0067 12 0 0 0 1.12E+07 4.37E+06 - - - 3.6311 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19023.19023.2 0.0572 16-Aug R.YLTVAAVFR.G "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 5 1038.5862 2.97 60425 19023 2 1038.587011 520.3004 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3609.4 - 8.55E+06 - - - 0.7655 - 1.718 0.429 - 213.8 1 2 0 0.0008 9 0 0 0 1.30E+09 4.38E+08 - - - 3.775 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.19028.19028.2 0.00112 14/18 K.IEVIEIMTDR[166.11].G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1227.6408 0.88 60428 19028 2 1227.639881 614.8277 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3610 - 1.82E+06 - - - -0.7844 - 2.567 0.354 - 839.9 1 2 0 -0.001 10 0 0 0 8.15E+07 9.28E+07 - - - 4.2868 0.9923 230117_WJC_METTL3_WT_vs_EV_F07.19029.19029.2 0.000293 18-Nov K.IEVIEIMTDR.G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1217.6326 0.88 60429 19029 2 1217.641302 609.8236 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3610.1 - 1.38E+06 - - - 7.168 - 2.47 0.384 - 499.7 1 2 0 0.0087 10 0 0 0 8.15E+07 9.28E+07 - - - 4.3984 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.19031.19031.2 0.484 16-Aug R.VEFILEQMR.L sp|O00232|PSD12_HUMAN 1 1163.6009 2.26 60431 19031 2 1163.599083 582.8077 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.53 3610.4 - 1.14E+06 - - - -1.5443 - 2.008 0.38 - 291.8 1 2 0 -0.0018 9 0 0 0 1.45E+07 6.43E+06 - - - 3.864 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.19032.19032.2 0.00704 14-Jun K.VFGFDSFK.T "sp|O94762|RECQ5_HUMAN,tr|J3KTQ2|J3KTQ2_HUMAN" 2 945.4596 0.47 60432 19032 2 945.461941 473.7371 ATP-dependent DNA helicase Q5 OS=Homo sapiens OX=9606 GN=RECQL5 PE=1 SV=2 5.81 3610.5 - 881204 - - - 2.4559 - 1.342 0.325 - 92.1 1 2 0 0.0023 8 0 0 0 7.97E+06 1.71E+07 - - - 2.3279 0.9848 230117_WJC_METTL3_WT_vs_EV_F07.19042.19042.2 0.208 22-Nov R.APGSGLALLPLK.L "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 1135.6965 7.53 60439 19042 2 1135.699058 568.8555 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 8.8 3611.7 - 515688 - - - 2.2568 - 1.45 0.041 - 155.4 1 2 0 0.0026 12 0 0 0 7.58E+06 1.01E+06 - - - 0.3207 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19044.19044.2 0.00136 20-Dec R.LAVDLSEVVIK.W "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1184.7016 0.09 60441 19044 2 1184.701346 593.3581 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.37 3612 - 453483 - - - -0.2482 - 2.225 0.385 - 341.7 1 2 0 -0.0003 11 0 0 0 8.51E+06 9.82E+07 - - - 4.048 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19045.19045.2 0.0104 24-Nov K.DIPVLVATDVAAR[166.11].G "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1348.759 2.41 60442 19045 2 1348.759743 675.3868 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3612.1 - 120273 - - - 0.5613 - 2.148 0.365 - 245.2 1 2 0 0.0008 13 0 0 0 1.10E+07 4.59E+06 - - - 3.6989 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19050.19050.2 0.00079 14-Aug R.DFVNYLVR[166.11].L sp|Q08211|DHX9_HUMAN 1 1034.5425 0.88 60445 19050 2 1034.543664 518.2785 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.84 3612.6 - 1.72E+07 - - - 1.1725 - 1.639 0.373 - 273.8 1 2 0 0.0012 8 0 0 0 2.47E+08 2.81E+08 - - - 3.2857 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19051.19051.2 1.42E-05 20-Dec R.LLDMDGIIVEK.Q sp|Q14152|EIF3A_HUMAN 1 1244.6686 1.09 60446 19051 2 1244.669898 623.3416 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.03 3612.6 - 2.19E+06 - - - 1.0228 - 2.531 0.343 - 276.2 1 2 0 0.0013 11 0 0 0 3.74E+07 3.43E+07 - - - 4.0861 1 230117_WJC_METTL3_WT_vs_EV_F07.19061.19061.2 1.24E-06 24-Dec R.TPFTTSQLLALER[166.11].K sp|P35548|MSX2_HUMAN 1 1485.8067 4.28 60456 19061 2 1485.808528 743.9106 Homeobox protein MSX-2 OS=Homo sapiens OX=9606 GN=MSX2 PE=1 SV=3 5.66 3613.7 - 384571 - - - 1.2545 - 2.794 0.501 - 382.2 1 2 0 0.0019 13 0 0 0 6.78E+06 1.58E+06 - - - 5.3778 1 230117_WJC_METTL3_WT_vs_EV_F07.19068.19068.2 2.39E-05 20-Nov K.TPPPVLIFAEK.K sp|Q9UJV9|DDX41_HUMAN 1 1210.6962 1.75 60462 19068 2 1210.696787 606.3554 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3614.3 - 1.48E+07 - - - 0.5171 - 1.946 0.517 - 365.1 1 2 0 0.0006 11 0 0 0 9.40E+07 5.37E+07 - - - 4.6604 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19069.19069.2 0.000485 20-Sep R.IGFVGFPSVGK.S sp|Q9Y295|DRG1_HUMAN 1 1106.6124 1.75 60463 19069 2 1106.613126 554.3135 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 8.75 3614.4 - 1.25E+07 - - - 0.628 - 1.687 0.405 - 196.3 1 2 0 0.0007 11 0 0 0 5.41E+07 3.09E+07 - - - 3.4468 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19074.19074.2 5.50E-06 20-Oct R.YLLEQDFPGMR.L "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN" 2 1367.6544 2.88 60468 19074 2 1367.656338 684.8345 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.37 3614.8 - 1.03E+06 - - - 1.4375 - 1.951 0.37 - 372.7 1 2 0 0.002 11 0 0 0 2.25E+06 7.78E+05 - - - 3.5812 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.19075.19075.2 0.00911 22-Aug K.YMGAAAMYLISK.R "sp|Q9H7Z7|PGES2_HUMAN,tr|A0A7I2V5T7|A0A7I2V5T7_HUMAN,tr|A6NHH0|A6NHH0_HUMAN,tr|X6RJ95|X6RJ95_HUMAN,tr|A0A7I2V5X6|A0A7I2V5X6_HUMAN" 5 1317.6461 1.62 60469 19075 2 1317.648687 659.8303 Prostaglandin E synthase 2 OS=Homo sapiens OX=9606 GN=PTGES2 PE=1 SV=1 8.5 3614.9 - 916447 - - - 1.9512 - 1.299 0.308 - 103.4 1 2 0 0.0026 12 0 0 0 2.86E+06 1.76E+06 - - - 2.0034 0.9662 230117_WJC_METTL3_WT_vs_EV_F07.19076.19076.2 6.33 12-May R.FAGVDIR.V "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 776.4181 1.83 60470 19076 2 776.419199 389.2163 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 5.84 3615.1 - 504723 - - - 1.4309 - 1.131 0.049 - 79.7 2 2 0 0.0011 7 0 0 0 2.51E+06 1.37E+06 - - - -0.3418 0.9239 230117_WJC_METTL3_WT_vs_EV_F07.19081.19081.2 5.28 20-Jun K.TPPPVLIFAEK[136.11].K sp|Q9UJV9|DDX41_HUMAN 1 1218.7104 1.7 60473 19081 2 1218.711781 610.3625 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3615.8 - 4.77E+06 - - - 1.1652 - 0.781 0.103 - 50.5 1 2 0 0.0014 11 0 0 0 9.13E+07 5.36E+07 - - - -0.8674 1 230117_WJC_METTL3_WT_vs_EV_F07.19084.19084.2 7.91E-05 16-Oct K.GFGFVSFER[166.11].H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1054.5112 0.99 60476 19084 2 1054.509026 528.2629 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3616 - 1.27E+06 - - - -2.0152 - 1.953 0.49 - 409.6 1 2 0 -0.0021 9 0 0 0 3.03E+08 3.07E+08 - - - 4.596 0.9919 230117_WJC_METTL3_WT_vs_EV_F07.19087.19087.2 0.0261 16-Jul K.ILVTPWDYR.L sp|Q8TF46|DI3L1_HUMAN 1 1161.6182 0.62 60479 19087 2 1161.621577 581.8164 DIS3-like exonuclease 1 OS=Homo sapiens OX=9606 GN=DIS3L PE=1 SV=2 5.84 3616.2 - 350534 - - - 2.8684 - 1.542 0.096 - 142.6 1 2 0 0.0033 9 0 0 0 2.31E+06 3.72E+06 - - - 1.0019 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19089.19089.2 0.000482 20-Aug R.LAQPYVGVFLK.R "sp|P36776|LONM_HUMAN,tr|K7EQF8|K7EQF8_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN" 4 1233.7121 -1 60481 19089 2 1233.713662 617.8633 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 8.59 3616.4 - 101675 - - - 1.2296 - 1.612 0.378 - 132.3 1 2 0 0.0015 11 0 0 0 0.00E+00 0.00E+00 - - - 3.1241 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19092.19092.2 1.69E-05 16-Oct K.GFGFVSFER.H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1044.5029 0.99 60482 19092 2 1044.503444 523.2587 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3616.8 - 3.33E+06 - - - 0.539 - 1.806 0.441 - 426.7 1 2 0 0.0006 9 0 0 0 3.03E+08 3.07E+08 - - - 4.0082 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19094.19094.2 0.102 18-Oct R.TLDLPIYVTR.V "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 5 1189.6707 0.69 60484 19094 2 1189.672959 595.8426 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.5 3617 - 5.80E+06 - - - 1.9207 - 1.712 0.376 - 343.9 1 2 0 0.0023 10 0 0 0 1.23E+07 1.78E+07 - - - 3.3182 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19095.19095.2 0.042 14/22 K.IIENELEGFGIR.L sp|Q9Y295|DRG1_HUMAN 1 1388.73 1.15 60485 19095 2 1388.732284 695.3723 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3617.1 - 2.84E+06 - - - 1.6591 - 2.431 0.407 - 666.5 1 2 0 0.0023 12 0 0 0 8.67E+06 7.53E+06 - - - 4.3837 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19096.19096.2 0.0258 22-Dec K.IIENELEGFGIR[166.11].L sp|Q9Y295|DRG1_HUMAN 1 1398.7383 1.15 60486 19096 2 1398.739972 700.3764 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3617.2 - 1.97E+06 - - - 1.2311 - 2.439 0.428 - 412.9 1 2 0 0.0017 12 0 0 0 8.67E+06 7.53E+06 - - - 4.5476 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19097.19097.2 0.00125 16-Sep K.GLDFALLQK.V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1003.5702 1.23 60487 19097 2 1003.572622 502.7924 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3617.3 - 1.96E+06 - - - 2.3815 - 1.885 0.404 - 253.3 1 2 0 0.0024 9 0 0 0 2.60E+07 2.11E+07 - - - 3.8582 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19098.19098.2 0.00395 16-Sep K.GLDFALLQK[136.11].V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1011.5844 1.37 60488 19098 2 1011.586686 506.7995 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3617.4 - 1.68E+06 - - - 2.2282 - 1.771 0.425 - 209.9 1 2 0 0.0023 9 0 0 0 3.14E+07 2.29E+07 - - - 3.8329 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19099.19099.2 0.00773 14-Aug R.DLTDYLMK.L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 997.479 1.13 60489 19099 2 997.481409 499.7468 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3617.6 - 1.43E+06 - - - 2.381 - 1.487 0.376 - 187.3 1 2 0 0.0024 8 0 0 0 3.80E+07 3.36E+07 - - - 3.014 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.19101.19101.2 0.118 14-Aug R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 0.71 60491 19101 2 898.52568 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 3617.8 - 830314 - - - 2.2971 - 1.538 0.237 - 158.8 1 2 0 0.0021 8 0 0 0 7.44E+06 1.04E+07 - - - 2.0892 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19102.19102.2 0.000564 14-Sep R.ITNWLVLK.N "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN,tr|H3BRT3|H3BRT3_HUMAN" 3 985.5961 1.93 60492 19102 2 985.598094 493.8053 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 8.75 3618 - 593416 - - - 2.0708 - 1.77 0.343 - 183 1 2 0 0.002 8 0 0 0 4.58E+06 2.38E+06 - - - 3.2958 0.9914 230117_WJC_METTL3_WT_vs_EV_F07.19107.19107.2 0.838 16-Aug K.SELSYELDR.L sp|Q96M29|TEKT5_HUMAN 1 1110.5193 145.55 60495 19107 2 1110.523138 556.2669 Tektin-5 OS=Homo sapiens OX=9606 GN=TEKT5 PE=1 SV=1 4.14 3618.6 - 3.21E+06 - - - 3.4389 - 1.42 0.16 - 157.4 1 2 0 0.0038 9 0 0 0 2.82E+07 1.94E+05 - - - 1.236 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.19108.19108.2 0.0163 12-Jun K.DYVDLFR.H sp|P78527|PRKDC_HUMAN 1 926.4498 0.37 60496 19108 2 926.451011 464.2322 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.21 3618.7 - 1.67E+06 - - - 1.3266 - 1.386 0.216 - 172.4 1 2 0 0.0012 7 0 0 0 1.16E+07 3.17E+07 - - - 1.6703 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19110.19110.2 2.41E-05 14/22 K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 1.99 60498 19110 2 1263.693147 632.853 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3619 - 1.70E+06 - - - 1.3698 - 2.196 0.465 - 482.6 1 2 0 0.0017 12 0 0 0 1.34E+07 6.76E+06 - - - 4.5447 1 230117_WJC_METTL3_WT_vs_EV_F07.19118.19118.2 8.51E-05 15/24 R.ILLAEVPTMAVEK[136.11].V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1420.8091 6.63 60506 19118 2 1420.810371 711.4118 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3620 - 557446 - - - 0.9023 - 2.637 0.501 - 712.7 1 2 0 0.0013 13 0 0 0 2.23E+07 3.37E+06 - - - 5.2296 1 230117_WJC_METTL3_WT_vs_EV_F07.19119.19119.2 3.36E-07 16/20 M.PPYTVVYFPVR.G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1336.718 1.18 60507 19119 2 1336.719276 669.3663 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3620.1 - 476293 - - - 0.9852 - 2.952 0.556 - 1252.2 1 2 0 0.0013 11 0 0 0 5.61E+07 4.76E+07 - - - 6.0756 1 230117_WJC_METTL3_WT_vs_EV_F07.19123.19123.2 8.80E-05 24-Oct R.LDYLGVSYGLTPR[166.11].L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1462.7695 0.8 60511 19123 2 1462.774894 732.3921 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.83 3620.6 - 306781 - - - 3.6533 - 2.191 0.498 - 172.2 1 2 0 0.0053 13 0 0 0 3.07E+06 3.85E+06 - - - 4.7306 1 230117_WJC_METTL3_WT_vs_EV_F07.19124.19124.2 6.61E-06 24-Dec R.LDYLGVSYGLTPR.L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1452.7613 0.79 60512 19124 2 1452.766161 727.3879 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.83 3620.7 - 302821 - - - 3.3598 - 2.355 0.557 - 401.8 1 2 0 0.0049 13 0 0 0 3.07E+06 3.90E+06 - - - 5.3518 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19126.19126.2 0.0032 20-Jul K.MPC[160.03]LYLQTLAR.H "sp|O75592|MYCB2_HUMAN,tr|A0A804HL12|A0A804HL12_HUMAN,tr|A0A499FJI4|A0A499FJI4_HUMAN,tr|A0A804HIR9|A0A804HIR9_HUMAN,tr|A0A804HJ25|A0A804HJ25_HUMAN,tr|A0A804HKQ1|A0A804HKQ1_HUMAN" 6 1364.6945 -1 60514 19126 2 1364.697444 683.3545 E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens OX=9606 GN=MYCBP2 PE=1 SV=4 7.98 3621 - 153988 - - - 2.1844 - 1.606 0.387 - 141.7 1 2 0 0.003 11 0 0 0 0.00E+00 0.00E+00 - - - 3.18 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.19128.19128.2 0.0116 18-Sep K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.18 60515 19128 2 1086.646565 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3621.3 - 1.71E+06 - - - 2.608 - 1.855 0.342 - 229.6 1 2 0 0.0028 10 0 0 0 4.39E+08 3.72E+08 - - - 3.2908 0.9944 230117_WJC_METTL3_WT_vs_EV_F07.19129.19129.2 0.0346 16-Jun R.SPTWFGIPR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1069.5584 1 60516 19129 2 1069.562058 535.7865 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3621.4 - 586605 - - - 3.3874 - 1.369 0.218 - 91.3 1 2 0 0.0036 9 0 0 0 3.64E+08 3.63E+08 - - - 1.5587 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.19130.19130.2 0.0306 14-Aug R.DLTDYLMK[136.11].L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 1005.4932 1.13 60517 19130 2 1005.494401 503.7539 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3621.4 - 3.41E+06 - - - 1.1606 - 1.321 0.301 - 186.3 1 2 0 0.0012 8 0 0 0 3.80E+07 3.36E+07 - - - 2.1034 0.9955 230117_WJC_METTL3_WT_vs_EV_F07.19131.19131.2 1.14 12-Jun R.EYLYFLK.H sp|Q8N1N4|K2C78_HUMAN 1 974.5113 24.57 60518 19131 2 974.512531 488.2629 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 6.1 3621.5 - 2.36E+06 - - - 1.2427 - 1.235 0.182 - 118.8 1 2 0 0.0012 7 0 0 0 2.50E+07 1.02E+06 - - - 1.0537 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19132.19132.2 0.000999 16-Nov K.LTQILSYLR.Q sp|Q13123|RED_HUMAN 1 1105.6495 1.58 60519 19132 2 1105.650498 553.832 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3621.6 - 2.03E+06 - - - 0.8619 - 2.31 0.393 - 596.2 1 2 0 0.001 9 0 0 0 5.07E+07 3.21E+07 - - - 4.3656 1 230117_WJC_METTL3_WT_vs_EV_F07.19133.19133.2 1.39E-07 17/20 M.PPYTVVYFPVR[166.11].G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1346.7262 1.18 60520 19133 2 1346.726857 674.3704 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3621.7 - 1.99E+06 - - - 0.4663 - 3.097 0.534 - 1421.1 1 2 0 0.0006 11 0 0 0 5.61E+07 4.76E+07 - - - 6.043 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19135.19135.2 0.187 16-Nov K.LTQILSYLR[166.11].Q sp|Q13123|RED_HUMAN 1 1115.6578 1.54 60522 19135 2 1115.66041 558.8362 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3621.9 - 1.53E+06 - - - 2.326 - 2.319 0.406 - 599.9 1 2 0 0.0026 9 0 0 0 4.91E+07 3.19E+07 - - - 4.4724 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19136.19136.2 0.0404 14-Sep K.IDILTELR[166.11].D "sp|O00139|KIF2A_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 981.5734 1.21 60523 19136 2 981.574633 491.794 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.37 3622 - 1.06E+06 - - - 1.2388 - 2.012 0.257 - 275.4 1 2 0 0.0012 8 0 0 0 3.73E+07 3.09E+07 - - - 3.0474 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.19137.19137.2 0.0268 20-Sep R.TVPILFASTVR.R sp|Q6P1M0|S27A4_HUMAN 1 1202.7023 0.39 60524 19137 2 1202.705957 602.3584 Long-chain fatty acid transport protein 4 OS=Homo sapiens OX=9606 GN=SLC27A4 PE=1 SV=1 9.41 3622.1 - 883460 - - - 3.0332 - 1.692 0.303 - 251.9 1 2 0 0.0036 11 0 0 0 7.85E+06 2.02E+07 - - - 2.7005 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19138.19138.2 2.37E-06 22-Dec K.NIEDVIAQGIGK.L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1255.6772 2.14 60525 19138 2 1255.678176 628.8459 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3622.2 - 661103 - - - 0.7645 - 2.134 0.469 - 266.5 1 2 0 0.001 12 0 0 0 1.45E+07 6.76E+06 - - - 4.4992 0.9319 230117_WJC_METTL3_WT_vs_EV_F07.19139.19139.2 0.437 12-Aug R.WLLELSK[136.11].K sp|P35573|GDE_HUMAN 1 895.5259 0.94 60526 19139 2 895.521891 448.7702 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 6 3622.3 - 648813 - - - -4.4253 - 1.612 0.108 - 173.9 1 2 0 -0.004 7 0 0 0 1.12E+07 1.19E+07 - - - 1.3504 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.19140.19140.3 0.000895 Dec-36 R.DFLLK[136.11]PELLR[166.11].A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1260.7561 1.11 60527 19140 3 1260.757567 421.2593 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3622.4 - 642309 - - - 1.1802 - 2.238 0.471 - 170 1 2 0 0.0015 10 0 0 0 1.69E+07 1.52E+07 - - - 6.1434 1 230117_WJC_METTL3_WT_vs_EV_F07.19142.19142.2 5.71E-07 Oct-34 K.SSGPTSLFAVTVAPPGAR.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1713.905 1.29 60529 19142 2 1713.904212 857.9598 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3622.7 - 61931.2 - - - -0.4504 - 2.057 0.523 - 127.3 1 2 0 -0.0008 18 0 0 0 7.13E+05 5.51E+05 - - - 4.6769 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19144.19144.2 0.000541 13/20 R.LMMDPLTGLNR[166.11].G "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1269.6449 0.82 60530 19144 2 1269.64586 635.8297 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.84 3622.9 - 3.48E+06 - - - 0.7687 - 2.082 0.364 - 528 1 2 0 0.001 11 0 0 0 9.92E+06 1.22E+07 - - - 3.713 0.8506 230117_WJC_METTL3_WT_vs_EV_F07.19145.19145.2 0.104 12-Aug R.FLEIGKF.D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 852.4745 1.6 60531 19145 2 852.475151 427.2445 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6 3623.1 - 1.56E+06 - - - 0.7156 - 1.508 0.185 - 165.9 1 1 0 0.0006 7 0 0 0 4.74E+06 2.96E+06 - - - 1.7088 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19146.19146.3 0.00254 Sep-36 R.DFLLKPELLR.A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1242.7336 1.13 60532 19146 3 1242.735045 415.2518 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3623.1 - 4.04E+06 - - - 1.1555 - 1.739 0.375 - 104.1 1 2 0 0.0014 10 0 0 0 1.69E+07 1.50E+07 - - - 4.3364 0.9947 230117_WJC_METTL3_WT_vs_EV_F07.19147.19147.2 0.957 12-Jul R.WLLELSK.K sp|P35573|GDE_HUMAN 1 887.5117 0.63 60533 19147 2 887.512832 444.7631 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 6 3623.2 - 2.44E+06 - - - 1.3273 - 1.424 0.122 - 240.3 2 2 0 0.0012 7 0 0 0 7.84E+06 1.24E+07 - - - 0.9272 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.19149.19149.2 8.23E-06 18-Nov K.C[160.03]LEEFELLGK[136.11].A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1244.6202 1.27 60535 19149 2 1244.619181 623.3174 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3623.3 - 2.01E+06 - - - -0.8388 - 1.925 0.473 - 338.6 1 2 0 -0.001 10 0 0 0 5.66E+06 4.44E+06 - - - 4.3623 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19150.19150.2 6.18E-05 18-Nov K.C[160.03]LEEFELLGK.A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1236.606 1.27 60536 19150 2 1236.607271 619.3103 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3623.4 - 1.65E+06 - - - 1.0076 - 1.839 0.473 - 350.4 1 2 0 0.0012 10 0 0 0 5.66E+06 4.44E+06 - - - 4.2347 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19151.19151.2 0.378 16-Oct R.FDLIGLEGR.V "sp|Q6ZRS2|SRCAP_HUMAN,tr|A0A0C4DFX4|A0A0C4DFX4_HUMAN,tr|A0A0A0MS59|A0A0A0MS59_HUMAN,tr|A0A087X0E3|A0A087X0E3_HUMAN" 4 1018.5447 0.7 60537 19151 2 1018.54777 510.2796 Helicase SRCAP OS=Homo sapiens OX=9606 GN=SRCAP PE=1 SV=3 4.37 3623.5 - 1.58E+06 - - - 2.9699 - 2.151 0.285 - 387.9 1 2 0 0.003 9 0 0 0 5.66E+06 8.13E+06 - - - 3.3609 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19152.19152.2 0.000116 18-Sep K.GIFLGDDEWR[166.11].E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1216.5752 1.73 60538 19152 2 1216.575937 609.2949 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3623.6 - 1.26E+06 - - - 0.6 - 2.021 0.46 - 272 1 2 0 0.0007 10 0 0 0 2.02E+07 1.17E+07 - - - 4.4023 0.999 230117_WJC_METTL3_WT_vs_EV_F07.19154.19154.2 0.000753 14-Sep K.LGTLFAFK[136.11].K sp|Q6F5E8|CARL2_HUMAN 1 903.5309 3.78 60540 19154 2 903.533975 452.7727 "Capping protein, Arp2\3 and myosin-I linker protein 2 OS=Homo sapiens OX=9606 GN=CARMIL2 PE=1 SV=2" 8.75 3623.9 - 952404 - - - 3.359 - 1.734 0.36 - 167 1 2 0 0.003 8 0 0 0 1.34E+07 3.55E+06 - - - 3.3591 1 230117_WJC_METTL3_WT_vs_EV_F07.19162.19162.2 4.02E-05 24-Nov R.ILLAEVPTMAVEK.V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1412.7949 6.63 60547 19162 2 1412.79597 707.4047 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3624.8 - 525740 - - - 0.7651 - 2.159 0.501 - 358 1 2 0 0.0011 13 0 0 0 2.23E+07 3.37E+06 - - - 4.7164 1 230117_WJC_METTL3_WT_vs_EV_F07.19164.19164.2 6.46E-06 18-Oct K.GIFLGDDEWR.E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1206.5669 1.74 60548 19164 2 1206.567934 604.2907 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3625 - 3.27E+06 - - - 0.8263 - 2.118 0.568 - 339.1 1 2 0 0.001 10 0 0 0 2.02E+07 1.16E+07 - - - 5.3307 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.19165.19165.2 0.161 16-Jun K.VQWGVFVPR.D sp|Q8IWA0|WDR75_HUMAN 1 1086.5974 1.29 60549 19165 2 1086.59813 544.306 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 9.72 3625 - 2.24E+06 - - - 0.6258 - 1.382 0.155 - 121.4 1 2 0 0.0007 9 0 0 0 1.20E+07 9.34E+06 - - - 1.1216 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19167.19167.2 0.00329 16-Aug K.VQWGVFVPR[166.11].D sp|Q8IWA0|WDR75_HUMAN 1 1096.6057 1.35 60551 19167 2 1096.605857 549.3101 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 9.72 3625.2 - 1.70E+06 - - - 0.1249 - 1.585 0.409 - 353.7 1 2 0 0.0001 9 0 0 0 1.34E+07 9.90E+06 - - - 3.3943 1 230117_WJC_METTL3_WT_vs_EV_F07.19168.19168.2 7.67E-06 14/20 K.MALDIEIATYR[166.11].K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1304.6674 1.31 60552 19168 2 1304.670385 653.341 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3625.2 - 1.67E+06 - - - 2.2933 - 2.859 0.572 - 986.8 1 2 0 0.003 11 0 0 0 1.82E+07 1.39E+07 - - - 6.1066 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19169.19169.2 0.000199 16-Nov K.ASSLISLLK.Q "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 930.575 2.48 60553 19169 2 930.57565 466.2948 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.8 3625.4 - 1.64E+06 - - - 0.7168 - 2.172 0.406 - 492.4 1 2 0 0.0007 9 0 0 0 2.38E+07 9.58E+06 - - - 4.2835 0.978 230117_WJC_METTL3_WT_vs_EV_F07.19172.19172.2 1.67 14-Jun R.VPNAEEIF.- "sp|Q9BW92|SYTM_HUMAN,tr|F6S7Q7|F6S7Q7_HUMAN,tr|U3KQG0|U3KQG0_HUMAN" 3 917.4494 - 60556 19172 2 917.449902 459.732 "Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1" 3.79 3625.6 - 1.16E+06 - - - 0.4949 - 1.054 0.114 - 105.3 1 2 0 0.0005 8 0 0 0 - - - - - 0.0415 0.9942 230117_WJC_METTL3_WT_vs_EV_F07.19173.19173.2 0.526 16-Jul R.LLIDEAILK[136.11].C "sp|P49591|SYSC_HUMAN,tr|Q5T5C7|Q5T5C7_HUMAN" 2 1034.6467 1.83 60557 19173 2 1034.647173 518.3306 "Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3" 4.37 3625.6 - 828158 - - - 0.4591 - 1.056 0.243 - 96.8 1 2 0 0.0005 9 0 0 0 7.02E+06 3.82E+06 - - - 0.9933 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19181.19181.2 2.28E-06 16-Oct K.MC[160.03]LFAGFQR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1128.5209 0.92 60563 19181 2 1128.524348 565.2677 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3626.6 - 604402 - - - 3.0943 - 2.113 0.37 - 455.8 1 2 0 0.0035 9 0 0 0 6.01E+07 6.54E+07 - - - 3.937 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19184.19184.2 0.00139 18-Oct R.DFLLKPELLR.A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1242.7336 1.84 60566 19184 2 1242.735766 622.3741 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3627 - 328490 - - - 1.7357 - 2.019 0.423 - 359.6 1 2 0 0.0022 10 0 0 0 4.17E+06 2.27E+06 - - - 4.1258 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19185.19185.2 0.00229 16-Oct K.FALNSLLQR[166.11].Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1070.6112 2.31 60567 19185 2 1070.613857 536.3129 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.75 3627.1 - 307835 - - - 2.4827 - 1.967 0.418 - 410.5 1 2 0 0.0027 9 0 0 0 2.75E+07 1.19E+07 - - - 4.0847 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19192.19192.2 7.46E-05 20-Jul R.LMMDPLTGLNR.G "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1259.6366 0.83 60573 19192 2 1259.640199 630.8256 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.84 3628 - 356272 - - - 2.8461 - 1.697 0.393 - 138 1 2 0 0.0036 11 0 0 0 9.92E+06 1.20E+07 - - - 3.3733 1 230117_WJC_METTL3_WT_vs_EV_F07.19193.19193.2 0.00166 16-Nov K.FALNSLLQR.Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1060.6029 1.88 60574 19193 2 1060.603765 531.3087 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.75 3628.1 - 1.75E+06 - - - 0.7882 - 2.283 0.464 - 431.6 1 2 0 0.0008 9 0 0 0 2.89E+07 1.54E+07 - - - 4.856 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19194.19194.2 0.00157 14-Sep R.LSFAVPFR[166.11].E sp|P78527|PRKDC_HUMAN 1 945.5312 1.3 60575 19194 2 945.532744 473.7729 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3628.2 - 1.62E+06 - - - 1.6774 - 1.776 0.309 - 292.7 1 2 0 0.0016 8 0 0 0 2.24E+07 1.72E+07 - - - 3.055 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.19195.19195.2 0.0161 14-Aug R.LSFAVPFR.E sp|P78527|PRKDC_HUMAN 1 935.5229 1.27 60576 19195 2 935.52255 468.7687 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3628.2 - 1.50E+06 - - - -0.3613 - 1.914 0.265 - 204 1 2 0 -0.0003 8 0 0 0 2.19E+07 1.72E+07 - - - 2.9561 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.19196.19196.2 0.00149 16-Nov K.IIDGLLVMR[166.11].K "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1038.6135 3.16 60577 19196 2 1038.615772 520.314 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.84 3628.3 - 968546 - - - 2.1808 - 2.106 0.256 - 330.9 1 2 0 0.0023 9 0 0 0 7.27E+07 2.30E+07 - - - 3.0858 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.19197.19197.2 0.259 18-Sep K.LEPAFLSGLR.C "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1101.6182 2.09 60578 19197 2 1101.62023 551.8164 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3628.4 - 926053 - - - 1.8019 - 1.703 0.215 - 181.3 1 2 0 0.002 10 0 0 0 2.08E+07 9.96E+06 - - - 2.1144 0.9802 230117_WJC_METTL3_WT_vs_EV_F07.19198.19198.2 0.313 16-Apr R.VLIFSQMVR.C "sp|Q9P2D1|CHD7_HUMAN,sp|O14646|CHD1_HUMAN,sp|Q9HCK8|CHD8_HUMAN,sp|Q3L8U1|CHD9_HUMAN,sp|O14647|CHD2_HUMAN,sp|Q8TD26|CHD6_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A1B0GTU9|A0A1B0GTU9_HUMAN,tr|A0A2R8Y840|A0A2R8Y840_HUMAN,tr|H0YJG4|H0YJG4_HUMAN" 10 1091.6161 0.47 60579 19198 2 1091.615849 546.8153 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.72 3628.5 - 890910 - - - -0.2629 - 1.082 0.191 - 48.6 5 2 0 -0.0003 9 0 0 0 8.46E+06 1.79E+07 - - - 0.3674 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19200.19200.2 0.0329 18-Sep R.LLLDTLQLSK.- "sp|O15357|SHIP2_HUMAN,tr|H7BXR2|H7BXR2_HUMAN" 2 1142.6911 2.6 60581 19200 2 1142.692923 572.3528 "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 OS=Homo sapiens OX=9606 GN=INPPL1 PE=1 SV=2" 5.84 3628.7 - 336099 - - - 1.6172 - 1.97 0.354 - 175.7 1 2 0 0.0018 10 0 0 0 4.38E+06 1.69E+06 - - - 3.5477 1 230117_WJC_METTL3_WT_vs_EV_F07.19201.19201.2 1.11E-05 16/26 R.FIAVGYVDDTQFVR.F "sp|P04439|HLAA_HUMAN,tr|A0A140T953|A0A140T953_HUMAN,tr|A0A140T941|A0A140T941_HUMAN,tr|A0A1W2PQS8|A0A1W2PQS8_HUMAN,tr|A0A0G2JI36|A0A0G2JI36_HUMAN,tr|A0A140T8W8|A0A140T8W8_HUMAN,tr|Q9GJ45|Q9GJ45_HUMAN,tr|Q53Z42|Q53Z42_HUMAN,tr|Q5RJ27|Q5RJ27_HUMAN,tr|Q53YP1|Q53YP1_HUMAN,tr|Q5SRN5|Q5SRN5_HUMAN,tr|A0A1W2PS24|A0A1W2PS24_HUMAN,tr|A0A0G2JIF2|A0A0G2JIF2_HUMAN,tr|A0A1W2PQD0|A0A1W2PQD0_HUMAN,tr|A0A1W2PRZ0|A0A1W2PRZ0_HUMAN,tr|A0A140T9U0|A0A140T9U0_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A0G2JPD3|A0A0G2JPD3_HUMAN,tr|A0A140T9W2|A0A140T9W2_HUMAN,tr|O78179|O78179_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|A0A1W2PPQ2|A0A1W2PPQ2_HUMAN,tr|A0A140T9T1|A0A140T9T1_HUMAN,tr|Q5SPM2|Q5SPM2_HUMAN,tr|Q5SUL5|Q5SUL5_HUMAN,tr|A0A140T8Y4|A0A140T8Y4_HUMAN,tr|A0A140T975|A0A140T975_HUMAN,tr|A0A140TA03|A0A140TA03_HUMAN,tr|A0A140TA13|A0A140TA13_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A1W2PSE7|A0A1W2PSE7_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|A0A1W2PPF8|A0A1W2PPF8_HUMAN,tr|D9J307|D9J307_HUMAN,tr|A0A140T937|A0A140T937_HUMAN,tr|Q5SRN7|Q5SRN7_HUMAN,tr|A0A1W2PR61|A0A1W2PR61_HUMAN,tr|A0A140T912|A0A140T912_HUMAN,tr|A0A140T9M0|A0A140T9M0_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN,tr|A0A1W2PS39|A0A1W2PS39_HUMAN,tr|A0A140T9Z6|A0A140T9Z6_HUMAN,tr|A0A140T9M5|A0A140T9M5_HUMAN,tr|A0A140T930|A0A140T930_HUMAN,tr|A0A140T9Z4|A0A140T9Z4_HUMAN,tr|B0UXQ0|B0UXQ0_HUMAN,tr|A0A0G2JL56|A0A0G2JL56_HUMAN" 48 1628.8199 5.89 60582 19201 2 1628.825768 815.4172 "HLA class I histocompatibility antigen, A alpha chain OS=Homo sapiens OX=9606 GN=HLA-A PE=1 SV=2" 4.21 3628.8 - 197970 - - - 3.6284 - 3.177 0.602 - 926.1 1 2 0 0.0059 14 0 0 0 3.26E+06 5.54E+05 - - - 6.3863 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19206.19206.2 0.00893 18-Sep R.LEPVIMELER[166.11].Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1237.6616 0.62 60585 19206 2 1237.662175 619.8381 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3629.4 - 6.27E+06 - - - 0.4807 - 1.857 0.411 - 341.7 1 2 0 0.0006 10 0 0 0 4.51E+07 7.31E+07 - - - 3.8042 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19207.19207.2 0.000697 16-Oct K.VFDAIMNFK[136.11].K sp|P13639|EF2_HUMAN 1 1091.5565 4.93 60586 19207 2 1091.556615 546.7855 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.81 3629.5 - 2.77E+06 - - - 0.1026 - 1.905 0.454 - 264 1 2 0 0.0001 9 0 0 0 7.69E+07 1.56E+07 - - - 4.2587 0.8591 230117_WJC_METTL3_WT_vs_EV_F07.19208.19208.2 1.04 14-Aug L.LALIDALR.D "sp|Q9NYL9|TMOD3_HUMAN,tr|H0YKU1|H0YKU1_HUMAN,tr|H0YNJ8|H0YNJ8_HUMAN" 3 883.5491 0.39 60587 19208 2 883.550297 442.7818 Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1 5.84 3629.6 - 1.19E+06 - - - 1.3525 - 1.472 0.201 - 256.2 1 1 0 0.0012 8 0 0 0 5.67E+06 1.47E+07 - - - 1.6912 0.999 230117_WJC_METTL3_WT_vs_EV_F07.19214.19214.2 0.146 14-Jul K.LDFNWVTR.W "sp|Q86W92|LIPB1_HUMAN,tr|F5GZP6|F5GZP6_HUMAN" 2 1049.5294 1.49 60593 19214 2 1049.531821 525.772 Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2 5.84 3630.4 - 650193 - - - 2.2782 - 1.659 0.283 - 126.3 1 2 0 0.0024 8 0 0 0 3.32E+06 2.23E+06 - - - 2.6572 0.9604 230117_WJC_METTL3_WT_vs_EV_F07.19218.19218.2 0.854 24-May R.LLPPEDTQELIFK[136.11].D sp|O60287|NPA1P_HUMAN 1 1549.8483 1.31 60597 19218 2 1549.852291 775.9314 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 4.14 3630.9 - 215175 - - - 2.568 - 1.19 0.058 - 57.5 2 2 0 0.004 13 0 0 0 3.37E+06 2.57E+06 - - - -0.2199 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.19222.19222.2 0.0409 14-Jul R.IPLNDLFR[166.11].C sp|P13473|LAMP2_HUMAN 1 996.5632 7.29 60599 19222 2 996.5647 499.2889 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3631.5 - 775734 - - - 1.5192 - 1.471 0.268 - 139.3 1 2 0 0.0015 8 0 0 0 1.12E+08 1.53E+07 - - - 2.184 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.19223.19223.2 0.136 16-Sep K.SGILPILVK.C sp|O00505|IMA4_HUMAN 1 938.6165 1.42 60600 19223 2 938.618645 470.3155 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3631.5 - 2.41E+06 - - - 2.3343 - 1.401 0.319 - 189.5 1 2 0 0.0022 9 0 0 0 3.96E+07 2.79E+07 - - - 2.3719 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19224.19224.2 0.0302 16-Oct K.SGILPILVK[136.11].C sp|O00505|IMA4_HUMAN 1 946.6307 1.42 60601 19224 2 946.632508 474.3226 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3631.7 - 2.10E+06 - - - 1.9585 - 1.449 0.363 - 193.5 1 2 0 0.0019 9 0 0 0 3.96E+07 2.79E+07 - - - 2.7945 0.9955 230117_WJC_METTL3_WT_vs_EV_F07.19225.19225.2 0.764 16-Jul K.GLSLGFLEK.K sp|Q9NU22|MDN1_HUMAN 1 962.5437 0.49 60602 19225 2 962.545638 482.2791 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6 3631.8 - 1.12E+06 - - - 2.0311 - 1.484 0.13 - 107.3 1 2 0 0.002 9 0 0 0 6.20E+06 1.26E+07 - - - 1.1426 0.9598 230117_WJC_METTL3_WT_vs_EV_F07.19230.19230.3 0.434 Nov-68 R.KSASFPPPPFYLNC[160.03]DTR[166.11]R.N sp|Q8NDH2|CC168_HUMAN 1 2162.0607 - 60607 19230 3 2162.055842 721.6942 Coiled-coil domain-containing protein 168 OS=Homo sapiens OX=9606 GN=CCDC168 PE=2 SV=2 9.31 3632.4 - 495760 - - - -2.2303 - 1.487 0.195 - 71.5 1 2 0 -0.0048 18 0 0 0 - - - - - 1.7007 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.19231.19231.2 0.000723 20-Sep K.GPILMELQTYR.Y "sp|P08559|ODPA_HUMAN,sp|P29803|ODPAT_HUMAN" 2 1319.6908 2.07 60608 19231 2 1319.697182 660.8527 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 6 3632.5 - 337023 - - - 4.8678 - 1.626 0.409 - 83 1 2 0 0.0064 11 0 0 0 8.03E+06 3.89E+06 - - - 3.3749 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.19233.19233.3 0.0104 Aug-36 R.LFDQAFGLPR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1162.6135 1.37 60610 19233 3 1162.615453 388.5451 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3632.8 - 268423 - - - 1.685 - 1.408 0.318 - 78.6 1 2 0 0.002 10 0 0 0 1.64E+06 1.20E+06 - - - 3.0841 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19241.19241.2 1.86E-05 16-Oct K.MC[160.03]LFAGFQR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1138.5291 0.91 60617 19241 2 1138.532435 570.2718 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3633.8 - 5.81E+06 - - - 2.9064 - 2.071 0.353 - 638.1 1 2 0 0.0033 9 0 0 0 5.97E+07 6.54E+07 - - - 3.7535 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.19242.19242.2 0.213 14-Jun R.IPLNDLFR.C sp|P13473|LAMP2_HUMAN 1 986.5549 5.41 60618 19242 2 986.556821 494.2847 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3633.8 - 1.49E+07 - - - 1.931 - 1.459 0.275 - 159.3 1 2 0 0.0019 8 0 0 0 1.17E+08 2.16E+07 - - - 2.2108 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19244.19244.2 0.0143 16-Sep K.IIDGLLVMR.K "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1028.6052 3.21 60620 19244 2 1028.606637 515.3099 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.84 3633.9 - 4.66E+06 - - - 1.3611 - 1.999 0.298 - 210.6 1 2 0 0.0014 9 0 0 0 7.53E+07 2.34E+07 - - - 3.2455 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19245.19245.2 0.121 16-Jul R.LQLPVWEYK[136.11].D sp|O43143|DHX15_HUMAN 1 1182.6528 1.61 60621 19245 2 1182.653558 592.3337 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 3634 - 4.19E+06 - - - 0.602 - 1.517 0.337 - 176.9 1 2 0 0.0007 9 0 0 0 7.36E+07 4.56E+07 - - - 2.7355 0.9809 230117_WJC_METTL3_WT_vs_EV_F07.19246.19246.2 1.99 14-May R.VLLLPLER.D sp|O95071|UBR5_HUMAN 1 951.6117 1.95 60622 19246 2 951.612232 476.8131 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3634 - 2.28E+06 - - - 0.5559 - 1.368 0.037 - 98.8 2 2 0 0.0005 8 0 0 0 3.52E+07 1.80E+07 - - - 0.1247 0.9935 230117_WJC_METTL3_WT_vs_EV_F07.19247.19247.2 4.17 14-May R.VLLLPLER[166.11].D sp|O95071|UBR5_HUMAN 1 961.62 1.87 60623 19247 2 961.62149 481.8173 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3634.1 - 1.39E+06 - - - 1.5775 - 1.342 0.117 - 84.8 1 2 0 0.0015 8 0 0 0 3.53E+07 1.88E+07 - - - 0.7919 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19253.19253.2 0.00225 24-Nov R.ALGLGLVSPAQLR.V "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|A8MRA7|A8MRA7_HUMAN" 3 1293.7769 2.97 60629 19253 2 1293.778228 647.8957 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 9.79 3634.7 - 513953 - - - 1.0489 - 2.463 0.261 - 493.9 1 2 0 0.0014 13 0 0 0 8.72E+06 2.94E+06 - - - 3.2817 0.8679 230117_WJC_METTL3_WT_vs_EV_F07.19261.19261.2 0.087 16-Jul S.GDLLSEVER.N "sp|O14513|NCKP5_HUMAN,tr|A0A0A0MSE4|A0A0A0MSE4_HUMAN,tr|A0A0A0MS79|A0A0A0MS79_HUMAN" 3 1016.5138 7.78 60635 19261 2 1016.517464 509.2642 Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=2 4.14 3635.8 - 2.12E+06 - - - 3.5661 - 1.729 0.286 - 214.9 1 1 0 0.0036 9 0 0 0 1.65E+08 2.12E+07 - - - 2.7363 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.19262.19262.2 0.0753 14-Sep K.MIDLIIPR.G sp|P54886|P5CS_HUMAN 1 969.5681 1.75 60636 19262 2 969.572553 485.7913 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 5.59 3635.8 - 1.25E+06 - - - 4.569 - 1.874 0.43 - 375.2 1 2 0 0.0044 8 0 0 0 1.41E+07 8.07E+06 - - - 4.1098 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.19266.19266.2 0.0271 12-Aug R.IQLLVFK[136.11].H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 867.5673 0.68 60640 19266 2 867.56773 434.7909 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3636.1 - 1.08E+06 - - - 0.4668 - 1.783 0.098 - 196.7 1 2 0 0.0004 7 0 0 0 3.73E+07 5.52E+07 - - - 1.5971 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.19268.19268.2 0.00203 18-Nov K.SVVTSIFGVK.N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1035.5964 1.85 60642 19268 2 1035.600372 518.8055 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3636.4 - 500085 - - - 3.7901 - 1.821 0.396 - 340.9 1 2 0 0.0039 10 0 0 0 5.56E+07 3.00E+07 - - - 3.6377 1 230117_WJC_METTL3_WT_vs_EV_F07.19274.19274.2 1.27E-06 24-Nov R.LLPGEEC[160.03]VLDGLR.V sp|O95248|MTMR5_HUMAN 1 1469.7548 1.6 60648 19274 2 1469.762192 735.8847 Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4 4.14 3637.1 - 171271 - - - 5.0192 - 2.274 0.597 - 396.3 1 2 0 0.0074 13 0 0 0 4.84E+06 3.03E+06 - - - 5.5566 0.997 230117_WJC_METTL3_WT_vs_EV_F07.19278.19278.2 0.383 12-Aug R.IQLLVFK.H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 859.5531 0.68 60650 19278 2 859.555574 430.7838 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3637.7 - 1.44E+06 - - - 2.8492 - 1.714 0.145 - 207.4 1 2 0 0.0024 7 0 0 0 3.73E+07 5.52E+07 - - - 1.8185 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.19280.19280.2 3.17 16-Sep R.LQLPVWEYK.D sp|O43143|DHX15_HUMAN 1 1174.6386 1.62 60652 19280 2 1174.640141 588.3266 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 3637.8 - 3.15E+06 - - - 1.2727 - 1.843 0.143 - 244.5 1 2 0 0.0015 9 0 0 0 7.39E+07 4.56E+07 - - - 1.8655 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.19281.19281.2 0.132 14-Aug K.GLLQLQWK[136.11].Q sp|O94826|TOM70_HUMAN 1 992.5899 1.21 60653 19281 2 992.591771 497.3022 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.75 3637.9 - 1.08E+06 - - - 1.9333 - 1.668 0.197 - 174.4 1 2 0 0.0019 8 0 0 0 1.43E+07 1.18E+07 - - - 2.0385 1 230117_WJC_METTL3_WT_vs_EV_F07.19282.19282.2 1.48E-05 18-Nov K.SVVTSIFGVK[136.11].N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1043.6106 1.88 60654 19282 2 1043.613182 522.8126 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3637.9 - 941051 - - - 2.4291 - 2.019 0.542 - 332.1 1 2 0 0.0025 10 0 0 0 5.48E+07 2.92E+07 - - - 5.0046 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.19286.19286.2 0.0827 22-Nov K.GALPLDTVTFYK[136.11].V sp|P30040|ERP29_HUMAN 1 1331.7217 1.55 60658 19286 2 1331.72424 666.8681 Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4 5.83 3638.3 - 380619 - - - 1.9418 - 1.945 0.206 - 343.6 1 2 0 0.0026 12 0 0 0 6.63E+06 4.27E+06 - - - 2.3121 0.9718 230117_WJC_METTL3_WT_vs_EV_F07.19287.19287.2 0.738 12-Jul R.IIIWNLR.S sp|Q14149|MORC3_HUMAN 1 926.5702 0.66 60659 19287 2 926.572803 464.2924 MORC family CW-type zinc finger protein 3 OS=Homo sapiens OX=9606 GN=MORC3 PE=1 SV=3 9.75 3638.4 - 357140 - - - 2.8395 - 1.293 0.034 - 144.5 1 2 0 0.0026 7 0 0 0 7.33E+06 1.12E+07 - - - 0.1055 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19288.19288.2 4.96E-05 24-Oct R.LLPGEEC[160.03]VLDGLR[166.11].V sp|O95248|MTMR5_HUMAN 1 1479.7631 1.6 60660 19288 2 1479.765872 740.8888 Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4 4.14 3638.6 - 267917 - - - 1.8834 - 2.037 0.485 - 190.7 1 2 0 0.0028 13 0 0 0 4.84E+06 3.03E+06 - - - 4.4484 0.999 230117_WJC_METTL3_WT_vs_EV_F07.19289.19289.2 0.00186 20-Aug K.ELFPIQMEGVK[136.11].L "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 1297.6832 1.1 60661 19289 2 1297.682253 649.8489 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.53 3638.7 - 194234 - - - -0.6989 - 1.643 0.409 - 159.5 1 2 0 -0.0009 11 0 0 0 8.93E+06 8.14E+06 - - - 3.4048 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.19292.19292.2 0.00278 16-Sep K.LLIYWASTR.E sp|P06312|KV401_HUMAN 1 1121.6233 692.49 60662 19292 2 1121.628726 561.8189 Immunoglobulin kappa variable 4-1 OS=Homo sapiens OX=9606 GN=IGKV4-1 PE=1 SV=1 8.75 3639.1 - 1.48E+06 - - - 4.8109 - 1.976 0.343 - 303 1 2 0 0.0054 9 0 0 0 3.56E+07 5.14E+04 - - - 3.5431 1 230117_WJC_METTL3_WT_vs_EV_F07.19293.19293.2 0.0041 14-Sep K.ILTPIIFK.E "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5L9|H7C5L9_HUMAN" 4 943.6106 0.75 60663 19293 2 943.615587 472.8126 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 8.75 3639.2 - 1.13E+06 - - - 5.2426 - 1.904 0.518 - 211.9 1 2 0 0.0049 8 0 0 0 2.47E+07 3.28E+07 - - - 4.8075 1 230117_WJC_METTL3_WT_vs_EV_F07.19296.19296.2 8.52E-05 22-Dec K.LSTIALALGVER.T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1241.7343 1.99 60666 19296 2 1241.737704 621.8744 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3639.4 - 1.04E+06 - - - 2.7115 - 2.581 0.48 - 487.1 1 2 0 0.0034 12 0 0 0 3.07E+07 1.54E+07 - - - 5.08 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19297.19297.2 0.000272 22-Aug K.LSTIALALGVER[166.11].T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1251.7426 1.99 60667 19297 2 1251.745512 626.8786 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3639.4 - 631234 - - - 2.3208 - 1.97 0.346 - 225 1 2 0 0.0029 12 0 0 0 3.07E+07 1.54E+07 - - - 3.3797 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.19303.19303.2 0.0667 14-Aug K.MIDLIIPR[166.11].G sp|P54886|P5CS_HUMAN 1 979.5764 1.75 60672 19303 2 979.579535 490.7955 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 5.59 3640.1 - 238254 - - - 3.2075 - 1.654 0.278 - 211.3 2 2 0 0.0031 8 0 0 0 1.41E+07 8.07E+06 - - - 2.4765 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.19306.19306.2 0.000663 16-Oct K.EAEILEVLR[166.11].H sp|P36551|HEM6_HUMAN 1 1080.6054 1.1 60674 19306 2 1080.602482 541.31 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.25 3640.6 - 1.77E+06 - - - -2.742 - 1.972 0.376 - 298.3 1 2 0 -0.003 9 0 0 0 2.30E+07 2.09E+07 - - - 3.7817 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19307.19307.2 0.000716 18-Aug K.SVPDEIILLR[166.11].S sp|Q9H9A6|LRC40_HUMAN 1 1163.6789 2.22 60675 19307 2 1163.680784 582.8467 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.37 3640.6 - 888767 - - - 1.5812 - 1.616 0.363 - 214 1 2 0 0.0018 10 0 0 0 4.37E+07 1.97E+07 - - - 3.0612 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.19308.19308.2 0.761 18-Jul R.LEPVIMELER.Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1227.6533 0.56 60676 19308 2 1227.653066 614.8339 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3640.7 - 572504 - - - -0.1988 - 1.627 0.14 - 125.2 1 2 0 -0.0002 10 0 0 0 3.90E+07 7.01E+07 - - - 1.4336 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.19311.19311.2 0.0563 20-Jul K.LIDFGSGALLK.D "sp|P11309|PIM1_HUMAN,sp|Q86V86|PIM3_HUMAN" 2 1132.6492 0.07 60679 19311 2 1132.652506 567.3319 Serine\threonine-protein kinase pim-1 OS=Homo sapiens OX=9606 GN=PIM1 PE=1 SV=4 5.84 3641.1 - 350976 - - - 2.9091 - 1.334 0.308 - 72.4 1 2 0 0.0033 11 0 0 0 4.33E+06 6.21E+07 - - - 2.0945 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19312.19312.2 6.35E-06 20-Oct R.FSTIEEFSYIR[166.11].R "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1400.6852 1.39 60680 19312 2 1400.687556 701.3499 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 4.53 3641.2 - 349303 - - - 1.7163 - 1.944 0.478 - 259.6 1 2 0 0.0024 11 0 0 0 6.41E+06 4.63E+06 - - - 4.3691 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.19315.19315.2 0.308 20-Jun K.LFGALTPLEPR[166.11].L "sp|O14617|AP3D1_HUMAN,tr|A0A087WYN6|A0A087WYN6_HUMAN,tr|A0A2R8Y4J3|A0A2R8Y4J3_HUMAN" 3 1222.6949 1.72 60683 19315 2 1222.696875 612.3547 AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1 6 3641.6 - 167263 - - - 1.5916 - 1.519 0.245 - 62.4 2 2 0 0.0019 11 0 0 0 6.20E+06 3.61E+06 - - - 1.8464 0.9952 230117_WJC_METTL3_WT_vs_EV_F07.19318.19318.2 0.348 14-Jul K.LAIVLFTK[136.11].E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 911.5935 1.87 60686 19318 2 911.595766 456.804 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3642 - 91837.7 - - - 2.4419 - 1.615 0.1 - 110.5 1 2 0 0.0022 8 0 0 0 5.80E+06 3.10E+06 - - - 1.2246 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.19324.19324.2 0.47 16-Jun K.VFSIGPVFR[166.11].A sp|P14868|SYDC_HUMAN 1 1030.5839 1.13 60690 19324 2 1030.583893 516.2992 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3642.6 - 2.16E+06 - - - -0.0281 - 1.448 0.206 - 102.6 1 2 0 0 9 0 0 0 5.34E+07 4.72E+07 - - - 1.6335 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19325.19325.2 0.0222 18-Jul R.IIVAIDGWPR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1148.6581 2.74 60691 19325 2 1148.658816 575.3364 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3642.7 - 2.21E+06 - - - 0.5807 - 1.583 0.327 - 135 1 2 0 0.0007 10 0 0 0 1.04E+08 3.81E+07 - - - 2.7381 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.19327.19327.2 0.000316 20-Sep K.ELFPIQMEGVK.L "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 1289.669 1.1 60693 19327 2 1289.673561 645.8418 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.53 3642.8 - 547366 - - - 3.5676 - 1.824 0.295 - 252 1 2 0 0.0046 11 0 0 0 8.93E+06 8.14E+06 - - - 2.8444 0.8663 230117_WJC_METTL3_WT_vs_EV_F07.19328.19328.2 1.75 16-Apr R.VGLEPPPGK.R "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 892.5018 2.37 60694 19328 2 892.503292 447.2582 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.97 3642.9 - 510778 - - - 1.6515 - 0.809 0.092 - 31.3 6 2 0 0.0015 9 0 0 0 5.20E+06 2.19E+06 - - - -1.2408 1 230117_WJC_METTL3_WT_vs_EV_F07.19331.19331.2 1.23E-06 20-Aug R.FSTIEEFSYIR.R "sp|Q6PI98|IN80C_HUMAN,tr|K7EQ79|K7EQ79_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1390.6769 1.39 60697 19331 2 1390.681127 696.3457 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 4.53 3643.1 - 412012 - - - 3.0525 - 2.133 0.504 - 234.2 1 2 0 0.0042 11 0 0 0 6.41E+06 4.63E+06 - - - 4.8115 0.9964 230117_WJC_METTL3_WT_vs_EV_F07.19338.19338.2 0.311 18-Oct R.IIVAIDGWPR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1138.6499 3.14 60702 19338 2 1138.651609 570.3322 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3643.9 - 9.52E+06 - - - 1.5193 - 2.013 0.032 - 335.8 1 2 0 0.0017 10 0 0 0 1.20E+08 3.81E+07 - - - 1.2297 1 230117_WJC_METTL3_WT_vs_EV_F07.19339.19339.2 1.84E-05 16-Nov R.QINWTVLYR.R "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1191.64 1.09 60703 19339 2 1191.641246 596.8273 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 8.75 3644 - 2.21E+06 - - - 1.0095 - 2.352 0.488 - 783.9 1 2 0 0.0012 9 0 0 0 4.88E+07 4.47E+07 - - - 5.1193 0.9956 230117_WJC_METTL3_WT_vs_EV_F07.19342.19342.2 0.000786 18-Sep K.LYSVVSQLIR[166.11].C "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 1186.6949 1.27 60706 19342 2 1186.700717 594.3547 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3644.4 - 600485 - - - 4.8774 - 1.579 0.339 - 205.2 1 2 0 0.0058 10 0 0 0 1.14E+07 9.04E+06 - - - 2.8181 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.19353.19353.2 0.36 20-Jun K.LFGALTPLEPR.L "sp|O14617|AP3D1_HUMAN,tr|A0A087WYN6|A0A087WYN6_HUMAN,tr|A0A2R8Y4J3|A0A2R8Y4J3_HUMAN" 3 1212.6867 1.68 60716 19353 2 1212.688199 607.3506 AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1 6 3645.8 - 425572 - - - 1.2699 - 1.21 0.276 - 75.4 1 2 0 0.0015 11 0 0 0 6.03E+06 3.59E+06 - - - 1.5947 1 230117_WJC_METTL3_WT_vs_EV_F07.19354.19354.2 2.50E-06 18-Nov R.LWIANYSLPR.A sp|O43172|PRP4_HUMAN 1 1231.6713 3.08 60717 19354 2 1231.673867 616.8429 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3645.9 - 2.03E+06 - - - 2.0492 - 2.175 0.537 - 622.3 1 2 0 0.0025 10 0 0 0 1.06E+08 3.44E+07 - - - 5.1754 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.19355.19355.2 1.4 14-Sep K.LAIVLFTK.E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 903.5793 1.87 60718 19355 2 903.580787 452.7969 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3646 - 575810 - - - 1.6014 - 1.678 0.11 - 171.3 1 2 0 0.0014 8 0 0 0 5.80E+06 3.10E+06 - - - 1.4141 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19356.19356.2 3.95E-05 16-Aug K.MDLVTYFGK.R sp|P09543|CN37_HUMAN 1 1072.5263 2.83 60719 19356 2 1072.52682 537.2704 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 5.59 3646.1 - 568804 - - - 0.4681 - 1.941 0.417 - 235.7 1 2 0 0.0005 9 0 0 0 1.41E+07 4.99E+06 - - - 4.0395 0.968 230117_WJC_METTL3_WT_vs_EV_F07.19358.19358.2 1.8 12-Jun K.QFLDYFK[136.11].T "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 967.4895 1.53 60721 19358 2 967.492157 484.752 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.83 3646.3 - 348030 - - - 2.7783 - 1.176 0.06 - 120.5 1 2 0 0.0027 7 0 0 0 1.17E+07 7.67E+06 - - - -0.003 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.19362.19362.2 0.055 12-Aug R.LDFLPLK.C "sp|Q8WV99|ZFN2B_HUMAN,tr|F8WEE4|F8WEE4_HUMAN,tr|E9PFU9|E9PFU9_HUMAN,tr|C9J1R6|C9J1R6_HUMAN,tr|B4DEN4|B4DEN4_HUMAN,tr|A0A087X0D9|A0A087X0D9_HUMAN,tr|B8ZZ56|B8ZZ56_HUMAN,tr|E7EV05|E7EV05_HUMAN" 8 844.5058 0.6 60725 19362 2 844.507369 423.2602 AN1-type zinc finger protein 2B OS=Homo sapiens OX=9606 GN=ZFAND2B PE=1 SV=1 5.84 3646.8 - 119166 - - - 1.8093 - 1.896 0.196 - 201.9 1 2 0 0.0015 7 0 0 0 6.91E+06 1.15E+07 - - - 2.5152 1 230117_WJC_METTL3_WT_vs_EV_F07.19366.19366.2 0.00458 20-Nov R.GVIFTEAFVAR.H sp|O94874|UFL1_HUMAN 1 1208.6554 1.45 60727 19366 2 1208.660365 605.335 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 6 3647.4 - 842905 - - - 4.1418 - 2.381 0.447 - 359.8 1 2 0 0.005 11 0 0 0 9.04E+06 6.22E+06 - - - 4.6878 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.19367.19367.2 0.0414 18-Jul R.LWIANYSLPR[166.11].A sp|O43172|PRP4_HUMAN 1 1241.6796 3.08 60728 19367 2 1241.682777 621.8471 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3647.4 - 2.11E+06 - - - 2.5482 - 1.765 0.173 - 158.4 2 2 0 0.0032 10 0 0 0 1.06E+08 3.44E+07 - - - 1.7692 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.19371.19371.2 0.00827 12-Jul K.FGFIGFK[136.11].S sp|Q9Y4C8|RBM19_HUMAN 1 822.452 0.96 60732 19371 2 822.454146 412.2333 Probable RNA-binding protein 19 OS=Homo sapiens OX=9606 GN=RBM19 PE=1 SV=3 8.75 3647.9 - 617535 - - - 2.6567 - 1.514 0.395 - 116.7 1 2 0 0.0022 7 0 0 0 4.34E+06 4.53E+06 - - - 3.272 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.19373.19373.2 0.0038 16-Jul K.LYQEMFAWK.M "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1214.5794 1.59 60734 19373 2 1214.582521 608.297 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3648.1 - 484143 - - - 2.5564 - 1.344 0.264 - 95.3 1 2 0 0.0031 9 0 0 0 4.88E+06 3.06E+06 - - - 1.8453 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19375.19375.2 0.00186 18-Sep K.ELPEYYELIR[166.11].K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1333.6793 1.65 60736 19375 2 1333.680981 667.8469 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3648.4 - 380762 - - - 1.2319 - 1.633 0.389 - 342 1 2 0 0.0016 10 0 0 0 1.80E+07 1.09E+07 - - - 3.2825 0.9922 230117_WJC_METTL3_WT_vs_EV_F07.19387.19387.2 0.00223 16-Jul R.LSYPTFFPR.F "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1126.5811 2.18 60746 19387 2 1126.577392 564.2978 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 8.75 3649.9 - 697132 - - - -3.3189 - 1.353 0.396 - 105.7 1 2 0 -0.0037 9 0 0 0 2.68E+07 1.23E+07 - - - 2.8393 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19388.19388.2 0.00145 18-Sep K.ELPEYYELIR.K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1323.6711 1.65 60747 19388 2 1323.672796 662.8428 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3650 - 609719 - - - 1.3055 - 1.655 0.458 - 326.9 1 2 0 0.0017 10 0 0 0 1.80E+07 1.09E+07 - - - 3.8295 0.9969 230117_WJC_METTL3_WT_vs_EV_F07.19389.19389.2 0.141 16-Aug K.IFAFDLDAK[136.11].R sp|Q96P11|NSUN5_HUMAN 1 1046.5528 0.7 60748 19389 2 1046.552062 524.2837 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 4.21 3650 - 345490 - - - -0.7023 - 1.499 0.25 - 103.7 1 2 0 -0.0007 9 0 0 0 9.12E+06 1.30E+07 - - - 2.0584 0.999 230117_WJC_METTL3_WT_vs_EV_F07.19390.19390.2 0.00272 16-Aug K.ISVNDFIIK[136.11].A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1055.6106 0.78 60749 19390 2 1055.613582 528.8126 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 3650.1 - 332577 - - - 2.7804 - 1.792 0.295 - 113.6 1 2 0 0.0029 9 0 0 0 9.89E+06 1.27E+07 - - - 2.9066 0.9969 230117_WJC_METTL3_WT_vs_EV_F07.19391.19391.2 0.311 14-Jul K.GLLDVLPK.N "sp|O95071|UBR5_HUMAN,tr|E7ET84|E7ET84_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 853.5273 2.58 60750 19391 2 853.528874 427.7709 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.84 3650.2 - 226003 - - - 1.8394 - 1.282 0.216 - 139.6 1 2 0 0.0016 8 0 0 0 2.24E+07 8.71E+06 - - - 1.3851 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19392.19392.2 6.38E-05 18-Aug R.FMEPYIFGSR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 1255.5935 1.13 60751 19392 2 1255.596591 628.804 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 6 3650.3 - 216095 - - - 2.4618 - 1.856 0.467 - 258.6 1 2 0 0.0031 10 0 0 0 5.66E+06 5.01E+06 - - - 4.2155 0.9819 230117_WJC_METTL3_WT_vs_EV_F07.19393.19393.2 0.37 12-Jul R.LWAELLR[166.11].T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN" 3 909.5312 1.77 60752 19393 2 909.535601 455.7729 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 6 3650.4 - 177160 - - - 4.8849 - 1.492 0.151 - 141.9 1 2 0 0.0044 7 0 0 0 5.83E+06 3.29E+06 - - - 1.4227 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19397.19397.2 0.0001 18-Sep R.FFLSSGLIDK[136.11].V sp|Q9BTV4|TMM43_HUMAN 1 1133.6212 0.88 60754 19397 2 1133.621705 567.8179 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 5.84 3651 - 926942 - - - 0.4358 - 1.816 0.453 - 174.6 1 2 0 0.0005 10 0 0 0 9.29E+06 1.06E+07 - - - 4.0521 0.9493 230117_WJC_METTL3_WT_vs_EV_F07.19398.19398.2 0.365 16-Jul K.ISVNDFIIK.A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1047.5964 0.81 60755 19398 2 1047.601086 524.8055 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 3651.1 - 846522 - - - 4.4282 - 1.167 0.123 - 74.8 1 2 0 0.0046 9 0 0 0 9.89E+06 1.22E+07 - - - 0.3948 1 230117_WJC_METTL3_WT_vs_EV_F07.19399.19399.2 9.43E-06 13/22 R.VVYSAFLMATPR.L sp|Q15029|U5S1_HUMAN 1 1353.7115 1.63 60756 19399 2 1353.714782 677.863 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.72 3651.2 - 715599 - - - 2.4296 - 2.641 0.563 - 619.5 1 2 0 0.0033 12 0 0 0 9.09E+06 5.57E+06 - - - 5.7536 0.899 230117_WJC_METTL3_WT_vs_EV_F07.19401.19401.2 0.281 20-Nov R.FLQSAKNIAER[166.11].V sp|Q9UJV3|TRIM1_HUMAN 1 1285.7018 - 60758 19401 2 1285.703096 643.8582 Probable E3 ubiquitin-protein ligase MID2 OS=Homo sapiens OX=9606 GN=MID2 PE=1 SV=3 8.75 3651.4 - 393643 - - - 1.0041 - 2.128 0.278 - 346.2 1 2 1 0.0013 11 0 0 0 - - - - - 3.1368 0.9948 230117_WJC_METTL3_WT_vs_EV_F07.19402.19402.2 0.00671 20-Sep R.GVIFTEAFVAR[166.11].H sp|O94874|UFL1_HUMAN 1 1218.6636 1.44 60759 19402 2 1218.670455 610.3391 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 6 3651.6 - 343448 - - - 5.6012 - 1.806 0.352 - 141 1 2 0 0.0068 11 0 0 0 8.94E+06 6.22E+06 - - - 3.2378 1 230117_WJC_METTL3_WT_vs_EV_F07.19403.19403.2 0.000101 13/22 R.LC[160.03]LTDEEVVFVR.L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1478.7439 8.66 60760 19403 2 1478.74657 740.3792 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3651.7 - 322428 - - - 1.7948 - 2.603 0.523 - 740 1 2 0 0.0027 12 0 0 0 5.07E+06 5.86E+05 - - - 5.4202 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19404.19404.2 0.0114 14-Jul K.GLLDVLPK[136.11].N "sp|O95071|UBR5_HUMAN,tr|E7ET84|E7ET84_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 861.5415 2.5 60761 19404 2 861.543398 431.778 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.84 3651.8 - 293142 - - - 2.1984 - 1.392 0.388 - 145.2 1 2 0 0.0019 8 0 0 0 2.17E+07 8.67E+06 - - - 2.9037 0.9911 230117_WJC_METTL3_WT_vs_EV_F07.19409.19409.2 0.115 12-Jul R.LWAELLR.T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN" 3 899.5229 0.96 60765 19409 2 899.521318 450.7687 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 6 3652.4 - 418606 - - - -1.7454 - 1.519 0.18 - 187.3 1 2 0 -0.0016 7 0 0 0 5.66E+06 5.90E+06 - - - 1.6946 0.999 230117_WJC_METTL3_WT_vs_EV_F07.19413.19413.2 0.192 16-Aug K.GVILLIVDK.A "sp|P78344|IF4G2_HUMAN,tr|H0YE44|H0YE44_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 8 968.627 1.75 60769 19413 2 968.627977 485.3208 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.84 3652.7 - 877670 - - - 0.9901 - 1.654 0.253 - 156.6 1 2 0 0.001 9 0 0 0 8.61E+06 4.93E+06 - - - 2.3651 1 230117_WJC_METTL3_WT_vs_EV_F07.19414.19414.2 4.66E-05 18-Sep R.SIPMTVDFIR.L sp|P00492|HPRT_HUMAN 1 1177.6165 1.68 60770 19414 2 1177.617506 589.8155 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 5.55 3652.8 - 866821 - - - 0.8288 - 1.964 0.519 - 365.3 1 2 0 0.001 10 0 0 0 1.78E+07 1.06E+07 - - - 4.7581 1 230117_WJC_METTL3_WT_vs_EV_F07.19416.19416.2 2.22E-06 13/24 V.ALVMLQEDELLSK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1495.8047 1.47 60772 19416 2 1495.805735 748.9096 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3653.1 - 365516 - - - 0.6705 - 2.712 0.415 - 569.1 1 1 0 0.001 13 0 0 0 2.59E+07 1.76E+07 - - - 4.6665 1 230117_WJC_METTL3_WT_vs_EV_F07.19421.19421.2 5.90E-05 14/22 K.VLGTEELYGYLK[136.11].K "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1391.7428 1.09 60775 19421 2 1391.74688 696.8787 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.53 3653.7 - 798854 - - - 2.9438 - 2.44 0.509 - 575.6 1 2 0 0.0041 12 0 0 0 1.56E+07 1.42E+07 - - - 5.1462 1 230117_WJC_METTL3_WT_vs_EV_F07.19422.19422.3 1.65E-05 15/56 K.LLQVASPFLEPHLVR.M "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1717.9879 2.86 60776 19422 3 1717.991359 573.6699 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 6.75 3653.8 - 610961 - - - 1.9983 - 3.169 0.455 - 319.1 1 2 0 0.0034 15 0 0 0 8.83E+06 3.08E+06 - - - 6.6215 1 230117_WJC_METTL3_WT_vs_EV_F07.19423.19423.2 2.67E-05 17/24 R.IPSPLGYAAIPIK.F sp|Q9Y3A4|RRP7A_HUMAN 1 1338.7911 1.43 60777 19423 2 1338.793687 670.4028 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 8.59 3653.9 - 691498 - - - 1.9144 - 2.975 0.522 - 1078.8 1 2 0 0.0026 13 0 0 0 6.07E+07 4.25E+07 - - - 5.6938 1 230117_WJC_METTL3_WT_vs_EV_F07.19424.19424.2 0.000131 13/26 K.VLELDPALAPVVSR.E "sp|O00170|AIP_HUMAN,tr|A0A804HKK3|A0A804HKK3_HUMAN,tr|A0A804HKL7|A0A804HKL7_HUMAN,tr|A0A804HJ46|A0A804HJ46_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN" 6 1477.8504 4.93 60778 19424 2 1477.851918 739.9325 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 4.37 3654 - 489168 - - - 1.0069 - 2.815 0.506 - 432.3 1 2 0 0.0015 14 0 0 0 3.14E+07 6.37E+06 - - - 5.375 1 230117_WJC_METTL3_WT_vs_EV_F07.19425.19425.2 1.54E-06 15/24 R.IPSPLGYAAIPIK[136.11].F sp|Q9Y3A4|RRP7A_HUMAN 1 1346.8053 1.44 60779 19425 2 1346.806885 674.4099 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 8.59 3654.2 - 454713 - - - 1.159 - 2.213 0.536 - 331.7 1 2 0 0.0016 13 0 0 0 6.12E+07 4.25E+07 - - - 5.0381 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.19427.19427.2 0.00203 20-Sep K.MALDIEIAAYR[166.11].K "sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,sp|P12036|NFH_HUMAN,sp|P07196|NFL_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 6 1274.6568 1.3 60781 19427 2 1274.66045 638.3357 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.37 3654.4 - 303724 - - - 2.8408 - 1.705 0.357 - 127.7 1 2 0 0.0036 11 0 0 0 6.15E+06 4.73E+06 - - - 3.1201 1 230117_WJC_METTL3_WT_vs_EV_F07.19429.19429.2 0.000178 13/22 K.VLGTEELYGYLK.K "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1383.7286 1.09 60782 19429 2 1383.730112 692.8716 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.53 3654.7 - 1.51E+06 - - - 1.105 - 2.603 0.505 - 446.6 1 2 0 0.0015 12 0 0 0 1.56E+07 1.42E+07 - - - 5.2876 0.9817 230117_WJC_METTL3_WT_vs_EV_F07.19431.19431.2 0.00217 24-Aug K.AALEAVGGTVVLE.- sp|P52815|RM12_HUMAN 1 1227.6711 - 60783 19431 2 1227.679991 614.8428 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 4.24 3654.9 - 2.71E+07 - - - 7.2682 - 1.514 0.385 - 161.4 1 2 0 0.0089 13 0 0 0 - - - - - 2.9463 1 230117_WJC_METTL3_WT_vs_EV_F07.19432.19432.2 5.95E-07 15/24 V.ALVMLQEDELLSK.M sp|Q96A49|SYAP1_HUMAN 1 1487.7905 1.47 60784 19432 2 1487.797473 744.9025 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3655 - 1.07E+06 - - - 4.6653 - 2.965 0.52 - 792.8 1 1 0 0.0069 13 0 0 0 2.59E+07 1.76E+07 - - - 5.669 0.9656 230117_WJC_METTL3_WT_vs_EV_F07.19433.19433.2 0.0194 18-Sep R.VTIMGIYSIK[136.11].K "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 3 1131.6453 1.66 60785 19433 2 1131.65172 566.8299 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 8.56 3655.2 - 786124 - - - 5.6572 - 1.795 0.105 - 189.5 2 2 0 0.0064 10 0 0 0 1.67E+07 1.00E+07 - - - 1.313 0.9876 230117_WJC_METTL3_WT_vs_EV_F07.19434.19434.2 0.00902 16-Jul R.VLEALLPLK.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 994.6427 1.6 60786 19434 2 994.646108 498.3286 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3655.3 - 514834 - - - 3.4575 - 1.649 0.082 - 121 2 2 0 0.0034 9 0 0 0 1.44E+08 8.97E+07 - - - 0.9581 0.9944 230117_WJC_METTL3_WT_vs_EV_F07.19435.19435.2 0.146 14-Jul K.LFVGFLNR[166.11].A "sp|Q9NXE4|NSMA3_HUMAN,tr|H7C0W5|H7C0W5_HUMAN,tr|H7C2E2|H7C2E2_HUMAN,tr|H7C2J2|H7C2J2_HUMAN,tr|H7C1Q6|H7C1Q6_HUMAN,tr|H7C235|H7C235_HUMAN,tr|A0A7P0TB44|A0A7P0TB44_HUMAN,tr|A0A7P0T9J6|A0A7P0T9J6_HUMAN,tr|A0A7P0TB24|A0A7P0TB24_HUMAN" 9 974.5577 2.17 60787 19435 2 974.561595 488.2861 Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3 9.75 3655.4 - 500860 - - - 3.9895 - 1.335 0.272 - 109.5 1 2 0 0.0039 8 0 0 0 1.34E+07 6.17E+06 - - - 1.9202 0.9932 230117_WJC_METTL3_WT_vs_EV_F07.19436.19436.2 0.0924 14-Jun R.ILPWSTFR[166.11].L "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1028.5683 0.59 60788 19436 2 1028.57168 515.2914 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3655.5 - 474689 - - - 3.3133 - 1.173 0.248 - 115.9 1 2 0 0.0034 8 0 0 0 1.02E+07 1.74E+07 - - - 1.3529 1 230117_WJC_METTL3_WT_vs_EV_F07.19441.19441.2 7.40E-06 13/22 R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.3 60793 19441 2 1315.792351 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3656.1 - 165775 - - - 4.5433 - 2.44 0.562 - 505 1 2 0 0.006 12 0 0 0 2.70E+09 2.08E+09 - - - 5.5371 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.19443.19443.2 6.13E-05 20-Oct R.ELAYQTFEVLR.K "sp|Q13206|DDX10_HUMAN,tr|A0A3B3ISR7|A0A3B3ISR7_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 3 1367.7085 1 60795 19443 2 1367.714617 684.8615 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 4.53 3656.4 - 100117 - - - 4.4607 - 2.006 0.461 - 353 1 2 0 0.0061 11 0 0 0 2.25E+06 2.26E+06 - - - 4.3273 1 230117_WJC_METTL3_WT_vs_EV_F07.19444.19444.2 1.27E-05 14/26 R.WSSLAC[160.03]NIALDAVK.M "sp|P49368|TCPG_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1546.7814 999 60796 19444 2 1546.791885 774.398 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.83 3656.5 - 86351.2 - - - 6.8019 - 2.541 0.58 - 557.2 1 2 0 0.0105 14 0 0 0 3.58E+06 0.00E+00 - - - 5.6618 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19449.19449.2 0.0044 22-Nov R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.3 60799 19449 2 1323.804898 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3657.2 - 8.68E+06 - - - 3.2671 - 2.106 0.44 - 306.7 1 2 0 0.0043 12 0 0 0 2.70E+09 2.08E+09 - - - 4.2492 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19450.19450.2 0.00688 16-Oct R.VLEALLPLK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1002.6569 1.6 60800 19450 2 1002.660405 502.3357 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3657.3 - 3.67E+06 - - - 3.5266 - 2.026 0.473 - 377.8 1 2 0 0.0035 9 0 0 0 1.44E+08 8.97E+07 - - - 4.5761 1 230117_WJC_METTL3_WT_vs_EV_F07.19451.19451.2 3.06E-08 20-Oct R.FFDEESYSLLR.K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1404.6561 1.61 60801 19451 2 1404.65915 703.3353 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3657.4 - 2.27E+06 - - - 2.1386 - 2.186 0.611 - 217.7 1 2 0 0.003 11 0 0 0 1.21E+08 7.53E+07 - - - 5.6686 1 230117_WJC_METTL3_WT_vs_EV_F07.19452.19452.2 2.91E-11 13/20 R.FFDEESYSLLR[166.11].K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1414.6644 1.61 60802 19452 2 1414.666723 708.3395 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3657.5 - 1.87E+06 - - - 1.6308 - 2.612 0.502 - 418.5 1 2 0 0.0023 11 0 0 0 1.21E+08 7.53E+07 - - - 5.3454 1 230117_WJC_METTL3_WT_vs_EV_F07.19453.19453.2 0.0013 14/22 K.ATGILLYGLASR.L "sp|P47897|SYQ_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|F2Z2V6|F2Z2V6_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 9 1233.7081 1.73 60803 19453 2 1233.714551 617.8613 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 8.79 3657.6 - 1.87E+06 - - - 5.2111 - 2.544 0.431 - 626.2 1 2 0 0.0064 12 0 0 0 1.86E+07 1.07E+07 - - - 4.6792 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19454.19454.2 0.0232 14-Sep R.WALGQVFR[166.11].Q "sp|P26572|MGAT1_HUMAN,tr|D6RF69|D6RF69_HUMAN" 2 985.5373 1.34 60804 19454 2 985.539846 493.7759 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 9.75 3657.7 - 1.40E+06 - - - 2.5773 - 1.929 0.352 - 341.2 1 2 0 0.0025 8 0 0 0 1.87E+07 1.40E+07 - - - 3.6216 0.999 230117_WJC_METTL3_WT_vs_EV_F07.19459.19459.2 0.00413 13/24 K.LGLSLVVPGGGIK.K sp|Q99747|SNAG_HUMAN 1 1208.7493 2.92 60809 19459 2 1208.753118 605.3819 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3658.3 - 560555 - - - 3.1926 - 2.565 0.255 - 337 1 2 0 0.0039 13 0 0 0 1.38E+07 4.71E+06 - - - 3.3408 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.19464.19464.2 0.000147 20-Sep K.ELLDTELDLYK[136.11].K "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1358.7061 1.54 60814 19464 2 1358.714384 680.3603 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 3.92 3658.9 - 277769 - - - 6.1242 - 1.935 0.437 - 240.5 1 2 0 0.0083 11 0 0 0 3.08E+06 2.00E+06 - - - 4.0518 1 230117_WJC_METTL3_WT_vs_EV_F07.19469.19469.2 0.000112 13/24 R.IITLTGPTNAIFK[136.11].A sp|Q15365|PCBP1_HUMAN 1 1395.8217 3.64 60817 19469 2 1395.82254 698.9181 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3659.6 - 4.31E+06 - - - 0.6004 - 2.662 0.508 - 484.7 1 2 0 0.0008 13 0 0 0 2.84E+08 7.81E+07 - - - 5.3057 0.8648 230117_WJC_METTL3_WT_vs_EV_F07.19470.19470.2 0.0491 14-May K.NALESYAF.N "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 913.4181 - 60818 19470 2 913.419205 457.7164 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4 3659.6 - 3.56E+06 - - - 1.1572 - 1.209 0.288 - 94.7 1 1 0 0.0011 8 0 0 0 - - - - - 1.7402 0.865 230117_WJC_METTL3_WT_vs_EV_F07.19471.19471.2 0.172 14-Jul K.QQLLIGAY.A sp|Q99832|TCPH_HUMAN 1 904.5018 - 60819 19471 2 904.503402 453.2582 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 5.52 3659.8 - 1.49E+06 - - - 1.7512 - 1.249 0.279 - 189.2 1 1 0 0.0016 8 0 0 0 - - - - - 1.7718 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.19472.19472.2 0.0239 18-Jul K.LLPFLAPGAR.A "sp|Q9BTY7|HGH1_HUMAN,tr|E9PIX0|E9PIX0_HUMAN" 2 1053.6335 4.94 60820 19472 2 1053.633625 527.824 Protein HGH1 homolog OS=Homo sapiens OX=9606 GN=HGH1 PE=1 SV=1 9.75 3659.9 - 1.44E+06 - - - 0.1177 - 1.584 0.286 - 134 1 2 0 0.0001 10 0 0 0 5.73E+06 1.16E+06 - - - 2.4372 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19476.19476.2 0.0132 18-Jul R.VIEQLLVGLK.D "sp|Q9BTW9|TBCD_HUMAN,tr|A0A804HJ32|A0A804HJ32_HUMAN,tr|A0A804HKT8|A0A804HKT8_HUMAN,tr|A0A804HHW7|A0A804HHW7_HUMAN,tr|A0A804HL21|A0A804HL21_HUMAN,tr|A0A804HKB9|A0A804HKB9_HUMAN,tr|A0A804HJY5|A0A804HJY5_HUMAN,tr|A0A804HI02|A0A804HI02_HUMAN,tr|A0A804HIU1|A0A804HIU1_HUMAN,tr|A0A804HJ57|A0A804HJ57_HUMAN,tr|A0A804HLF8|A0A804HLF8_HUMAN,tr|A0A804HL62|A0A804HL62_HUMAN,tr|A0A804HIC0|A0A804HIC0_HUMAN,tr|J3KR97|J3KR97_HUMAN,tr|A0A804HI57|A0A804HI57_HUMAN,tr|A0A804HIN6|A0A804HIN6_HUMAN,tr|A0A804HLI2|A0A804HLI2_HUMAN" 17 1110.7012 1.34 60824 19476 2 1110.703123 556.3579 Tubulin-specific chaperone D OS=Homo sapiens OX=9606 GN=TBCD PE=1 SV=2 5.97 3660.3 - 1.29E+06 - - - 1.6899 - 1.671 0.301 - 91 1 2 0 0.0019 10 0 0 0 5.08E+06 3.80E+06 - - - 2.6967 0.9948 230117_WJC_METTL3_WT_vs_EV_F07.19477.19477.2 0.00805 18-Oct K.VPSLVGSFIR[166.11].S "sp|P78417|GSTO1_HUMAN,tr|Q5TA02|Q5TA02_HUMAN" 2 1083.6316 0.88 60825 19477 2 1083.636555 542.8231 Glutathione S-transferase omega-1 OS=Homo sapiens OX=9606 GN=GSTO1 PE=1 SV=2 9.72 3660.4 - 1.15E+06 - - - 4.5726 - 1.757 0.239 - 195.1 1 2 0 0.005 10 0 0 0 8.56E+06 9.72E+06 - - - 2.3779 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19479.19479.2 0.00875 13/24 K.LGLSLVVPGGGIK[136.11].K sp|Q99747|SNAG_HUMAN 1 1216.7635 2.92 60827 19479 2 1216.76543 609.389 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3660.7 - 1.10E+06 - - - 1.6199 - 2.09 0.349 - 363.4 1 2 0 0.002 13 0 0 0 1.38E+07 4.71E+06 - - - 3.51 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.19480.19480.3 0.00104 Nov-44 R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 0.98 60828 19480 3 1323.802836 442.2741 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3660.8 - 951895 - - - 1.7095 - 1.972 0.444 - 150.6 1 2 0 0.0023 12 0 0 0 1.73E+07 1.75E+07 - - - 5.3718 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.19481.19481.3 0.000168 13/44 R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 0.53 60829 19481 3 1315.787987 439.6027 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3660.9 - 907612 - - - 1.2266 - 2.23 0.463 - 192.8 1 2 0 0.0016 12 0 0 0 2.10E+07 3.96E+07 - - - 5.9246 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19483.19483.2 0.00166 18-Oct R.VIEQLLVGLK[136.11].D "sp|Q9BTW9|TBCD_HUMAN,tr|A0A804HJ32|A0A804HJ32_HUMAN,tr|A0A804HKT8|A0A804HKT8_HUMAN,tr|A0A804HHW7|A0A804HHW7_HUMAN,tr|A0A804HL21|A0A804HL21_HUMAN,tr|A0A804HKB9|A0A804HKB9_HUMAN,tr|A0A804HJY5|A0A804HJY5_HUMAN,tr|A0A804HI02|A0A804HI02_HUMAN,tr|A0A804HIU1|A0A804HIU1_HUMAN,tr|A0A804HJ57|A0A804HJ57_HUMAN,tr|A0A804HLF8|A0A804HLF8_HUMAN,tr|A0A804HL62|A0A804HL62_HUMAN,tr|A0A804HIC0|A0A804HIC0_HUMAN,tr|J3KR97|J3KR97_HUMAN,tr|A0A804HI57|A0A804HI57_HUMAN,tr|A0A804HIN6|A0A804HIN6_HUMAN,tr|A0A804HLI2|A0A804HLI2_HUMAN" 17 1118.7154 1.34 60831 19483 2 1118.717643 560.365 Tubulin-specific chaperone D OS=Homo sapiens OX=9606 GN=TBCD PE=1 SV=2 5.97 3661.1 - 876403 - - - 1.9639 - 2.161 0.445 - 218 1 2 0 0.0022 10 0 0 0 5.08E+06 3.80E+06 - - - 4.478 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19486.19486.2 0.0211 18-Sep K.LIAVLESIER[166.11].L "sp|Q9ULT8|HECD1_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN,tr|H0YJP0|H0YJP0_HUMAN" 3 1151.6789 3.96 60834 19486 2 1151.679942 576.8467 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 4.53 3661.5 - 574019 - - - 0.8666 - 1.878 0.336 - 160.2 1 2 0 0.001 10 0 0 0 8.14E+06 2.06E+06 - - - 3.2815 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.19487.19487.2 0.00259 22-Nov R.NIPGITLLNVSK[136.11].L "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1275.7642 0.84 60835 19487 2 1275.768803 638.8894 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.75 3661.7 - 511193 - - - 3.6182 - 1.894 0.32 - 249.5 1 2 0 0.0046 12 0 0 0 3.66E+06 4.36E+06 - - - 3.0836 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19493.19493.2 0.00395 18-Jun R.FLVPIESIER.A sp|Q14249|NUCG_HUMAN 1 1201.6707 3.6 60839 19493 2 1201.671235 601.8426 "Endonuclease G, mitochondrial OS=Homo sapiens OX=9606 GN=ENDOG PE=1 SV=4" 4.53 3662.4 - 1.13E+06 - - - 0.4669 - 1.518 0.36 - 130.9 1 2 0 0.0006 10 0 0 0 2.99E+07 8.29E+06 - - - 2.8649 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19494.19494.2 0.00429 16-Sep K.LPFPIIDDR.N sp|P30041|PRDX6_HUMAN 1 1084.5917 1.34 60840 19494 2 1084.591068 543.3031 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.21 3662.5 - 1.95E+06 - - - -0.579 - 1.935 0.418 - 393 1 2 0 -0.0006 9 0 0 0 1.40E+08 1.05E+08 - - - 4.0379 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.19498.19498.2 0.000471 14-Sep K.LVYVDLLR.E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 989.591 1.97 60844 19498 2 989.59545 495.8028 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.84 3662.8 - 610415 - - - 4.5302 - 1.706 0.391 - 342.3 1 2 0 0.0045 8 0 0 0 4.14E+07 2.11E+07 - - - 3.5385 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19504.19504.2 0.00211 16-Nov K.TLEEILLER.A "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 3 1114.6234 1.91 60848 19504 2 1114.62325 558.319 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.25 3663.6 - 2.58E+06 - - - -0.1256 - 2.224 0.391 - 342.6 1 2 0 -0.0001 9 0 0 0 8.04E+07 4.21E+07 - - - 4.2413 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19506.19506.2 0.000996 20-Dec R.LLGLGVTDFSR[166.11].A "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 1186.6585 0.67 60850 19506 2 1186.658503 594.3365 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 5.84 3663.9 - 1.65E+06 - - - -0.0337 - 2.319 0.414 - 426.4 1 2 0 0 11 0 0 0 1.05E+07 1.58E+07 - - - 4.3743 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.19507.19507.2 0.128 16-Sep K.LSPEELLLR.W "sp|P13797|PLST_HUMAN,sp|Q14651|PLSI_HUMAN,sp|P13796|PLSL_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|C9JAM8|C9JAM8_HUMAN" 5 1068.6179 2.64 60851 19507 2 1068.617302 535.3162 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.53 3664 - 1.35E+06 - - - -0.569 - 1.556 0.242 - 144.3 1 2 0 -0.0006 9 0 0 0 6.44E+07 2.44E+07 - - - 2.1073 0.9477 230117_WJC_METTL3_WT_vs_EV_F07.19508.19508.2 2.59 16-Jul K.SLDLDGLSK.S sp|Q5W0B1|OBI1_HUMAN 1 946.4971 2.53 60852 19508 2 946.495969 474.2558 ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1 4.21 3664.1 - 1.14E+06 - - - -1.2235 - 1.145 0.09 - 114.3 1 2 0 -0.0012 9 0 0 0 1.10E+07 4.34E+06 - - - 0.0971 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.19510.19510.2 0.0502 16-Aug K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 4.91 60854 19510 2 1014.536662 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3664.4 - 831544 - - - 2.0571 - 1.63 0.196 - 134.1 1 2 0 0.0021 9 0 0 0 1.50E+07 3.06E+06 - - - 1.9015 1 230117_WJC_METTL3_WT_vs_EV_F07.19519.19519.2 0.000269 18-Dec R.LGLDDFESLK[136.11].V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1143.5903 0.43 60862 19519 2 1143.59022 572.8024 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3665.5 - 2.94E+07 - - - -0.0743 - 2.51 0.553 - 356.9 1 2 0 -0.0001 10 0 0 0 6.41E+07 1.50E+08 - - - 5.6942 0.9922 230117_WJC_METTL3_WT_vs_EV_F07.19523.19523.2 0.173 18-Aug K.LFLELEPQVR[166.11].D "sp|Q13098|CSN1_HUMAN,tr|A0A096LP07|A0A096LP07_HUMAN,tr|A8K070|A8K070_HUMAN,tr|C9JFE4|C9JFE4_HUMAN,tr|A0A096LPJ3|A0A096LPJ3_HUMAN" 5 1252.7055 2.24 60866 19523 2 1252.702585 627.36 COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4 4.53 3666 - 1.26E+06 - - - -2.3214 - 1.651 0.233 - 197.2 1 2 0 -0.0029 10 0 0 0 1.54E+07 6.86E+06 - - - 2.1605 0.9833 230117_WJC_METTL3_WT_vs_EV_F07.19525.19525.2 4.41 12-Jun M.GLLSILR.K "sp|P36405|ARL3_HUMAN,sp|Q14517|FAT1_HUMAN,tr|A0A087WVP1|A0A087WVP1_HUMAN" 3 770.5014 1.33 60868 19525 2 770.49998 386.258 ADP-ribosylation factor-like protein 3 OS=Homo sapiens OX=9606 GN=ARL3 PE=1 SV=2 9.75 3666.2 - 974668 - - - -1.8741 - 1.287 0.189 - 144.6 1 2 0 -0.0014 7 0 0 0 5.73E+06 4.30E+06 - - - 1.236 0.9875 230117_WJC_METTL3_WT_vs_EV_F07.19527.19527.2 0.155 18-Jul R.LLLQIPSTIR[166.11].S sp|Q16394|EXT1_HUMAN 1 1162.7313 1.07 60870 19527 2 1162.729405 582.3729 Exostosin-1 OS=Homo sapiens OX=9606 GN=EXT1 PE=1 SV=2 9.75 3666.4 - 823438 - - - -1.6418 - 1.437 0.176 - 132 1 2 0 -0.0019 10 0 0 0 5.26E+06 4.90E+06 - - - 1.3523 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19530.19530.2 0.0249 12-Sep R.SGMFWLR.F sp|P31930|QCR1_HUMAN 1 895.4374 1.13 60873 19530 2 895.436997 448.726 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 9.47 3666.8 - 506954 - - - -0.4992 - 1.746 0.382 - 362.6 1 2 0 -0.0004 7 0 0 0 9.28E+06 8.19E+06 - - - 3.6282 1 230117_WJC_METTL3_WT_vs_EV_F07.19531.19531.2 1.11E-06 13/24 R.TPFTTAQLLALER[166.11].K sp|P28360|MSX1_HUMAN 1 1469.8117 1.53 60874 19531 2 1469.809718 735.9132 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3667 - 500217 - - - -1.3818 - 2.729 0.555 - 525.9 1 2 0 -0.002 13 0 0 0 1.51E+07 9.90E+06 - - - 5.7162 0.9674 230117_WJC_METTL3_WT_vs_EV_F07.19532.19532.2 0.303 14-May K.GVLSDLTK.V "sp|Q8NG11|TSN14_HUMAN,tr|A6NEP9|A6NEP9_HUMAN,tr|H7BXY6|H7BXY6_HUMAN" 3 831.4702 6.98 60875 19532 2 831.468565 416.7424 Tetraspanin-14 OS=Homo sapiens OX=9606 GN=TSPAN14 PE=1 SV=1 5.84 3667.1 - 437872 - - - -1.946 - 1.295 0.163 - 59.1 4 2 0 -0.0016 8 0 0 0 1.07E+07 1.53E+06 - - - 0.7551 1 230117_WJC_METTL3_WT_vs_EV_F07.19535.19535.2 0.025 18-Sep R.LGLDDFESLK.V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1135.5761 0.43 60877 19535 2 1135.575451 568.7953 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3667.4 - 5.71E+06 - - - -0.5759 - 2.074 0.489 - 169.1 1 2 0 -0.0007 10 0 0 0 6.45E+07 1.51E+08 - - - 4.6887 0.999 230117_WJC_METTL3_WT_vs_EV_F07.19537.19537.2 0.0321 12-Jul R.SGMFWLR[166.11].F sp|P31930|QCR1_HUMAN 1 905.4457 1.13 60879 19537 2 905.446692 453.7301 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 9.47 3667.6 - 1.00E+06 - - - 1.0801 - 1.467 0.287 - 217.8 1 2 0 0.001 7 0 0 0 9.35E+06 8.27E+06 - - - 2.3747 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19538.19538.2 0.00368 16-Sep K.IPSVLFLGK.L sp|Q8IW75|SPA12_HUMAN 1 972.6008 999 60880 19538 2 972.601927 487.3077 Serpin A12 OS=Homo sapiens OX=9606 GN=SERPINA12 PE=1 SV=1 8.75 3667.7 - 906496 - - - 1.1546 - 2.042 0.397 - 190.2 1 2 0 0.0011 9 0 0 0 9.24E+06 0.00E+00 - - - 4.0383 1 230117_WJC_METTL3_WT_vs_EV_F07.19539.19539.2 1.63E-06 16/24 R.TPFTTAQLLALER.K sp|P28360|MSX1_HUMAN 1 1459.8035 1.53 60881 19539 2 1459.803204 730.909 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3667.9 - 577254 - - - -0.1884 - 2.902 0.549 - 793.8 1 2 0 -0.0003 13 0 0 0 1.51E+07 9.90E+06 - - - 5.8302 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19540.19540.2 0.0185 16-Sep R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 5.97 60882 19540 2 1006.569328 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3668 - 541807 - - - -0.5663 - 1.722 0.403 - 191.3 1 2 0 -0.0006 9 0 0 0 9.44E+06 1.58E+06 - - - 3.5897 0.994 230117_WJC_METTL3_WT_vs_EV_F07.19544.19544.2 0.0255 12-Jun K.LYSLLFR[166.11].R sp|Q9UDW1|QCR9_HUMAN 1 920.5359 1.15 60884 19544 2 920.536753 461.2752 Cytochrome b-c1 complex subunit 9 OS=Homo sapiens OX=9606 GN=UQCR10 PE=1 SV=3 8.75 3668.5 - 578235 - - - 0.9169 - 1.361 0.133 - 117.8 2 2 0 0.0008 7 0 0 0 1.12E+07 9.76E+06 - - - 0.8652 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.19546.19546.2 0.0333 18-Oct K.SLLFVNTLER.S "sp|Q9NY93|DDX56_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1190.6659 0.61 60885 19546 2 1190.670272 596.3402 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 5.72 3668.7 - 1.76E+06 - - - 3.6526 - 1.923 0.299 - 362.2 1 2 0 0.0043 10 0 0 0 1.25E+07 2.04E+07 - - - 3.0732 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.19547.19547.2 0.0191 16-Jul K.DVDLEFLAK[136.11].M "sp|P55072|TERA_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN" 6 1056.5583 0.78 60886 19547 2 1056.561301 529.2864 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.03 3668.8 - 1.96E+06 - - - 2.8621 - 1.329 0.338 - 112.3 1 2 0 0.003 9 0 0 0 9.24E+06 1.19E+07 - - - 2.3594 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.19549.19549.2 0.159 18-Jul R.LLLQIPSTIR.S sp|Q16394|EXT1_HUMAN 1 1152.723 1.07 60888 19549 2 1152.723959 577.3688 Exostosin-1 OS=Homo sapiens OX=9606 GN=EXT1 PE=1 SV=2 9.75 3669 - 1.29E+06 - - - 0.7938 - 1.461 0.189 - 121.9 1 2 0 0.0009 10 0 0 0 5.26E+06 4.90E+06 - - - 1.4949 1 230117_WJC_METTL3_WT_vs_EV_F07.19551.19551.2 7.81E-07 13/22 K.YDAFLASESLIK[136.11].Q sp|P62906|RL10A_HUMAN 1 1363.7115 0.82 60890 19551 2 1363.718101 682.863 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.37 3669.3 - 606461 - - - 4.8529 - 2.627 0.562 - 561.4 1 2 0 0.0066 12 0 0 0 4.00E+07 4.90E+07 - - - 5.7311 0.9966 230117_WJC_METTL3_WT_vs_EV_F07.19552.19552.2 0.358 12-Jun K.LLDFLC[160.03]R.Q "sp|O75170|PP6R2_HUMAN,sp|Q8IZL8|PELP1_HUMAN,tr|E7EV54|E7EV54_HUMAN,tr|C9JFV4|C9JFV4_HUMAN,tr|I3L445|I3L445_HUMAN" 5 935.4899 0.69 60891 19552 2 935.48995 468.7522 Serine\threonine-protein phosphatase 6 regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PPP6R2 PE=1 SV=2 5.83 3669.4 - 393447 - - - 0.0823 - 1.283 0.234 - 91.3 1 2 0 0.0001 7 0 0 0 3.92E+06 5.73E+06 - - - 1.5589 0.994 230117_WJC_METTL3_WT_vs_EV_F07.19556.19556.2 1.14 14-Aug R.LPLFGLGR[166.11].L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 881.5362 1.25 60893 19556 2 881.536141 441.7754 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3669.9 - 583502 - - - -0.1157 - 1.412 0.148 - 285.6 1 2 0 -0.0001 8 0 0 0 1.34E+08 1.07E+08 - - - 1.1746 0.9856 230117_WJC_METTL3_WT_vs_EV_F07.19557.19557.2 0.567 14-Jul R.LPLFGLGR.L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 871.528 1.25 60894 19557 2 871.528099 436.7713 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3670 - 436943 - - - 0.1446 - 1.276 0.089 - 174 1 2 0 0.0001 8 0 0 0 1.35E+08 1.08E+08 - - - 0.4334 0.9651 230117_WJC_METTL3_WT_vs_EV_F07.19564.19564.2 0.946 12-May K.ANYWWLR.H "sp|P31939|PUR9_HUMAN,tr|H7C1S2|H7C1S2_HUMAN" 2 1007.4977 1.4 60901 19564 2 1007.497545 504.7561 Bifunctional purine biosynthesis protein ATIC OS=Homo sapiens OX=9606 GN=ATIC PE=1 SV=3 8.79 3670.6 - 169225 - - - -0.1896 - 1.018 0.134 - 67.5 2 2 0 -0.0002 7 0 0 0 2.91E+06 2.08E+06 - - - -0.0473 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19570.19570.2 0.0384 18-Nov K.SLLFVNTLER[166.11].S "sp|Q9NY93|DDX56_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1200.6742 0.54 60905 19570 2 1200.674235 601.3444 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 5.72 3671.5 - 2.08E+06 - - - 0.035 - 2.352 0.35 - 450.4 1 2 0 0 10 0 0 0 1.28E+07 2.35E+07 - - - 4.0134 1 230117_WJC_METTL3_WT_vs_EV_F07.19571.19571.2 2.05E-06 15/24 R.IITLAGPTNAIFK.A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1357.7969 2.63 60906 19571 2 1357.799529 679.9057 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3671.5 - 2.89E+06 - - - 1.909 - 2.725 0.581 - 737.9 1 2 0 0.0026 13 0 0 0 2.44E+08 9.26E+07 - - - 5.9043 1 230117_WJC_METTL3_WT_vs_EV_F07.19572.19572.2 0.000309 14/24 R.ILDIDNVDLAMGK.M sp|O43615|TIM44_HUMAN 1 1415.733 2.32 60907 19572 2 1415.736129 708.8738 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3671.7 - 1.46E+06 - - - 2.1982 - 2.775 0.575 - 654.7 1 2 0 0.0031 13 0 0 0 1.34E+07 5.77E+06 - - - 5.9065 0.971 230117_WJC_METTL3_WT_vs_EV_F07.19574.19574.2 5.93 16-Aug R.MADLSELLK[136.11].E "sp|P30519|HMOX2_HUMAN,tr|I3L276|I3L276_HUMAN,tr|I3L159|I3L159_HUMAN,tr|I3L463|I3L463_HUMAN,tr|I3L4P8|I3L4P8_HUMAN,tr|A0A1B0GXH0|A0A1B0GXH0_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 8 1026.5511 2.22 60909 19574 2 1026.552974 514.2828 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 4.37 3671.9 - 572676 - - - 1.8421 - 1.176 0.039 - 124.7 1 2 0 0.0019 9 0 0 0 5.97E+06 2.69E+06 - - - -0.2025 0.9932 230117_WJC_METTL3_WT_vs_EV_F07.19575.19575.2 0.0354 18-Sep R.LTC[160.03]LGVWLDK[136.11].V sp|Q9NWT1|PK1IP_HUMAN 1 1211.6464 1.19 60910 19575 2 1211.649592 606.8305 p21-activated protein kinase-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAK1IP1 PE=1 SV=2 5.83 3672 - 559844 - - - 2.6501 - 1.6 0.112 - 172.7 2 2 0 0.0032 10 0 0 0 3.25E+06 2.73E+06 - - - 1.0447 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19576.19576.2 0.0587 16-Sep R.VVVLGLLPR.G "sp|Q15102|PA1B3_HUMAN,tr|M0R389|M0R389_HUMAN" 2 964.6433 1.44 60911 19576 2 964.645042 483.3289 Platelet-activating factor acetylhydrolase IB subunit alpha1 OS=Homo sapiens OX=9606 GN=PAFAH1B3 PE=1 SV=1 9.72 3672.2 - 558720 - - - 1.7675 - 1.937 0.276 - 262.2 1 2 0 0.0017 9 0 0 0 4.31E+06 2.99E+06 - - - 2.9917 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19577.19577.2 0.00816 13/24 R.ILDIDNVDLAMGK[136.11].M sp|O43615|TIM44_HUMAN 1 1423.7472 2.32 60912 19577 2 1423.749989 712.8809 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3672.3 - 490423 - - - 1.947 - 2.341 0.423 - 514.8 1 2 0 0.0028 13 0 0 0 1.34E+07 5.77E+06 - - - 4.3474 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.19578.19578.2 0.00208 20-Dec K.LWDLASGTLYK.E sp|O75529|TAF5L_HUMAN 1 1265.6656 1.24 60913 19578 2 1265.663342 633.8401 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 5.83 3672.4 - 445015 - - - -1.7754 - 1.929 0.393 - 519.4 1 2 0 -0.0022 11 0 0 0 1.14E+07 9.15E+06 - - - 3.7203 0.9951 230117_WJC_METTL3_WT_vs_EV_F07.19579.19579.3 0.0235 Nov-48 R.TPFTTAQLLALER[166.11].K sp|P28360|MSX1_HUMAN 1 1469.8117 1.59 60914 19579 3 1469.817202 490.9445 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3672.6 - 403844 - - - 3.71 - 1.863 0.222 - 141.2 1 2 0 0.0055 13 0 0 0 2.44E+06 1.54E+06 - - - 2.7005 1 230117_WJC_METTL3_WT_vs_EV_F07.19580.19580.2 0.000325 13/20 K.ILEAVTLVQLK[136.11].E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1233.7788 0.92 60915 19580 2 1233.780799 617.8967 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6 3672.7 - 362965 - - - 1.6405 - 2.515 0.469 - 403.2 1 2 0 0.002 11 0 0 0 3.30E+06 3.57E+06 - - - 4.9994 0.999 230117_WJC_METTL3_WT_vs_EV_F07.19582.19582.2 0.0138 28-Jul R.VLVVGAGGIGC[160.03]ELLK.N "sp|Q9UBT2|SAE2_HUMAN,tr|U3KQ55|U3KQ55_HUMAN,tr|K7EPL2|K7EPL2_HUMAN,tr|K7ES38|K7ES38_HUMAN" 4 1483.8432 -1 60917 19582 2 1483.847665 742.9289 SUMO-activating enzyme subunit 2 OS=Homo sapiens OX=9606 GN=UBA2 PE=1 SV=2 5.97 3673 - 292210 - - - 2.9848 - 1.642 0.391 - 93.6 1 2 0 0.0044 15 0 0 0 0.00E+00 0.00E+00 - - - 3.1468 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.19590.19590.2 0.113 18-Aug K.AIDLFTDAIK.L "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 1105.6019 0.59 60923 19590 2 1105.602188 553.8082 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 4.21 3673.8 - 3.71E+06 - - - 0.237 - 1.617 0.187 - 150.4 1 2 0 0.0003 10 0 0 0 3.74E+07 6.35E+07 - - - 1.7635 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19591.19591.2 4.16E-06 20-Oct K.VGEVTYVELFK.D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1282.6809 1.87 60924 19591 2 1282.682555 642.3477 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.53 3673.9 - 2.46E+06 - - - 1.2864 - 2.306 0.427 - 351.5 1 2 0 0.0016 11 0 0 0 5.20E+07 2.77E+07 - - - 4.4546 1 230117_WJC_METTL3_WT_vs_EV_F07.19592.19592.2 7.81E-07 14/20 K.VGEVTYVELFK[136.11].D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1290.6951 1.87 60925 19592 2 1290.695343 646.3548 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.53 3673.9 - 1.28E+06 - - - 0.1844 - 2.8 0.609 - 891.6 1 2 0 0.0002 11 0 0 0 5.20E+07 2.77E+07 - - - 6.3244 1 230117_WJC_METTL3_WT_vs_EV_F07.19593.19593.2 3.94E-06 22-Nov K.VVLEGPAPWGFR.L "sp|Q9NR12|PDLI7_HUMAN,tr|D6RF83|D6RF83_HUMAN,tr|D6RAN1|D6RAN1_HUMAN,tr|H7BYK4|H7BYK4_HUMAN,tr|D6RH06|D6RH06_HUMAN" 5 1326.7085 5.77 60926 19593 2 1326.711595 664.3615 PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1 5.97 3674 - 884583 - - - 2.3653 - 2.439 0.535 - 464.6 1 2 0 0.0031 12 0 0 0 9.31E+06 1.61E+06 - - - 5.3374 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19594.19594.2 0.141 16-Nov K.WQALLVQIR[166.11].K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1135.6741 0.96 60927 19594 2 1135.675411 568.8443 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.75 3674.1 - 571769 - - - 1.1244 - 2.066 0.369 - 547.9 1 2 0 0.0013 9 0 0 0 7.49E+06 7.79E+06 - - - 3.8653 1 230117_WJC_METTL3_WT_vs_EV_F07.19596.19596.2 0.00127 16-Nov K.WQALLVQIR.K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1125.6659 0.96 60929 19596 2 1125.667643 563.8402 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.75 3674.3 - 454719 - - - 1.5804 - 2.205 0.452 - 590.9 1 2 0 0.0018 9 0 0 0 7.49E+06 7.79E+06 - - - 4.6665 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.19597.19597.2 0.48 12-Jul K.FDLIWNR.A "sp|Q5TC12|ATPF1_HUMAN,tr|I3L448|I3L448_HUMAN,tr|H0YEW4|H0YEW4_HUMAN,tr|A8MRA7|A8MRA7_HUMAN,tr|H0YD21|H0YD21_HUMAN" 5 962.4974 2.29 60930 19597 2 962.498824 482.256 ATP synthase mitochondrial F1 complex assembly factor 1 OS=Homo sapiens OX=9606 GN=ATPAF1 PE=1 SV=1 5.84 3674.4 - 417181 - - - 1.4784 - 1.749 0.069 - 221.9 1 2 0 0.0014 7 0 0 0 3.76E+06 1.65E+06 - - - 1.3215 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.19601.19601.2 0.0218 22-Jul K.LILISTNGSFIR[166.11].L sp|Q6UXN9|WDR82_HUMAN 1 1342.7848 0.89 60934 19601 2 1342.787909 672.3997 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 9.75 3674.9 - 185569 - - - 2.3109 - 1.485 0.277 - 123 1 2 0 0.0031 12 0 0 0 4.72E+06 5.34E+06 - - - 2.1264 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.19604.19604.2 0.0199 22-Sep K.VFFMAVDGVAPR.A "sp|Q8IZH2|XRN1_HUMAN,tr|F8WDA0|F8WDA0_HUMAN" 2 1307.6696 0.91 60937 19604 2 1307.67101 654.8421 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.81 3675.3 - 119188 - - - 1.0568 - 1.328 0.239 - 160.2 1 2 0 0.0014 12 0 0 0 1.90E+06 2.08E+06 - - - 1.5522 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19611.19611.2 0.00207 24-Oct R.IITLAGPTNAIFK[136.11].A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1365.8111 2.62 60942 19611 2 1365.8123 683.9128 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3676.3 - 1.52E+07 - - - 0.8515 - 2.254 0.392 - 261.3 1 2 0 0.0012 13 0 0 0 2.43E+08 9.26E+07 - - - 4.0218 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19612.19612.2 2.82E-05 18-Nov K.AVQFFVQALR.M "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 14 1177.6608 1 60943 19612 2 1177.66334 589.8377 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 9.79 3676.4 - 2.24E+06 - - - 2.1755 - 2.315 0.327 - 556.3 1 2 0 0.0026 10 0 0 0 1.35E+07 1.35E+07 - - - 3.7985 0.9934 230117_WJC_METTL3_WT_vs_EV_F07.19613.19613.2 0.0679 16-Sep K.NLLNLDVIK[136.11].K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1048.6372 0.97 60944 19613 2 1048.642403 525.3259 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3676.5 - 2.68E+06 - - - 4.9655 - 1.72 0.245 - 252.5 1 2 0 0.0052 9 0 0 0 1.29E+07 1.33E+07 - - - 2.4179 0.9886 230117_WJC_METTL3_WT_vs_EV_F07.19614.19614.2 0.367 16-Sep K.NLLNLDVIK.K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1040.623 0.97 60945 19614 2 1040.628172 521.3188 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3676.6 - 2.58E+06 - - - 4.9739 - 1.646 0.189 - 248 1 2 0 0.0052 9 0 0 0 1.30E+07 1.34E+07 - - - 1.8771 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.19615.19615.2 0.0201 13/22 K.LILISTNGSFIR.L sp|Q6UXN9|WDR82_HUMAN 1 1332.7765 0.89 60946 19615 2 1332.784758 667.3955 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 9.75 3676.8 - 1.41E+06 - - - 6.1691 - 2.286 0.394 - 575.9 1 2 0 0.0082 12 0 0 0 4.72E+06 5.34E+06 - - - 4.124 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.19617.19617.2 0.0301 14-Sep R.LWDFIENR.E "sp|Q9H000|MKRN2_HUMAN,tr|A0A7I2V5D2|A0A7I2V5D2_HUMAN,tr|A0A7I2YQI0|A0A7I2YQI0_HUMAN,tr|C9J494|C9J494_HUMAN" 4 1091.54 0.36 60948 19617 2 1091.544409 546.7773 Probable E3 ubiquitin-protein ligase makorin-2 OS=Homo sapiens OX=9606 GN=MKRN2 PE=1 SV=2 4.37 3677 - 1.20E+06 - - - 4.0447 - 1.835 0.289 - 299.5 1 2 0 0.0044 8 0 0 0 1.10E+07 3.08E+07 - - - 3.005 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.19618.19618.2 4.76E-06 13/20 K.ILEAVTLVQLK.E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1225.7646 0.92 60949 19618 2 1225.769829 613.8896 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6 3677.1 - 1.01E+06 - - - 4.2863 - 2.633 0.379 - 407.4 1 2 0 0.0053 11 0 0 0 3.30E+06 3.57E+06 - - - 4.4576 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.19619.19619.2 0.0165 18-Aug R.VLALEILPER[166.11].V sp|Q56A73|SPIN4_HUMAN 1 1161.6997 0.52 60950 19619 2 1161.705107 581.8571 Spindlin-4 OS=Homo sapiens OX=9606 GN=SPIN4 PE=1 SV=1 4.53 3677.2 - 830751 - - - 4.6716 - 2.027 0.406 - 237.2 1 2 0 0.0054 10 0 0 0 1.84E+06 3.55E+06 - - - 4.0102 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.19620.19620.2 0.0181 14-Aug R.LWLLDDSK.T "sp|O43639|NCK2_HUMAN,sp|P16333|NCK1_HUMAN,tr|E7EPF5|E7EPF5_HUMAN,tr|E7ERP6|E7ERP6_HUMAN,tr|C9J0K5|C9J0K5_HUMAN,tr|C9K098|C9K098_HUMAN,tr|C9J869|C9J869_HUMAN,tr|C9JVV5|C9JVV5_HUMAN,tr|E9PEE2|E9PEE2_HUMAN,tr|H7C5C7|H7C5C7_HUMAN" 10 988.5229 1.44 60951 19620 2 988.526807 495.2687 Cytoplasmic protein NCK2 OS=Homo sapiens OX=9606 GN=NCK2 PE=1 SV=2 4.21 3677.4 - 561279 - - - 3.9048 - 1.799 0.23 - 190.1 1 2 0 0.0039 8 0 0 0 2.46E+06 1.71E+06 - - - 2.5096 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.19622.19622.2 3.02E-05 22-Nov K.LFGYEPTIYYPK.R "sp|Q8NCW5|NNRE_HUMAN,tr|A0A7P0Z426|A0A7P0Z426_HUMAN,tr|Q5T3I4|Q5T3I4_HUMAN,tr|A0A7P0T9Y2|A0A7P0T9Y2_HUMAN,tr|A0A7P0TAG8|A0A7P0TAG8_HUMAN,tr|Q5T3I3|Q5T3I3_HUMAN" 6 1489.7493 1.35 60953 19622 2 1489.754772 745.8819 NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2 6 3677.6 - 468609 - - - 3.6603 - 2.186 0.466 - 362.1 1 2 0 0.0055 12 0 0 0 3.77E+06 2.78E+06 - - - 4.5389 0.9855 230117_WJC_METTL3_WT_vs_EV_F07.19624.19624.2 1.1 26-Jul K.VVIGMDVAASEFYR.N "sp|P13929|ENOB_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN" 2 1555.7705 1.89 60955 19624 2 1555.772071 778.8925 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.37 3677.9 - 462699 - - - 1.0323 - 1.043 0.147 - 103.6 1 2 0 0.0016 14 0 0 0 1.51E+07 7.98E+06 - - - 0.2319 0.8725 230117_WJC_METTL3_WT_vs_EV_F07.19625.19625.2 0.0531 16-Sep L.GVLASDLQR[166.11].V "sp|O15381|NVL_HUMAN,tr|E9PH71|E9PH71_HUMAN,tr|F8WF01|F8WF01_HUMAN,tr|E7EWK7|E7EWK7_HUMAN,tr|E9PGD8|E9PGD8_HUMAN" 5 967.5326 0.52 60956 19625 2 967.535941 484.7736 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 5.84 3678 - 429714 - - - 3.4386 - 1.955 0.231 - 240 1 1 0 0.0033 9 0 0 0 2.30E+06 4.43E+06 - - - 2.6856 1 230117_WJC_METTL3_WT_vs_EV_F07.19627.19627.2 6.60E-08 22-Nov K.LFGYEPTIYYPK[136.11].R "sp|Q8NCW5|NNRE_HUMAN,tr|A0A7P0Z426|A0A7P0Z426_HUMAN,tr|Q5T3I4|Q5T3I4_HUMAN,tr|A0A7P0T9Y2|A0A7P0T9Y2_HUMAN,tr|A0A7P0TAG8|A0A7P0TAG8_HUMAN,tr|Q5T3I3|Q5T3I3_HUMAN" 6 1497.7635 1.35 60958 19627 2 1497.770239 749.889 NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2 6 3678.3 - 342167 - - - 4.4867 - 2.119 0.572 - 372 1 2 0 0.0067 12 0 0 0 3.77E+06 2.78E+06 - - - 5.2395 0.999 230117_WJC_METTL3_WT_vs_EV_F07.19628.19628.2 0.000498 13/24 R.VESPVLPPVLVPR.H "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN" 2 1400.8391 2.11 60959 19628 2 1400.844488 701.4268 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 5.97 3678.4 - 526059 - - - 3.8199 - 1.795 0.451 - 430.4 1 2 0 0.0054 13 0 0 0 3.81E+06 1.81E+06 - - - 3.8718 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.19633.19633.2 0.212 26-Jun R.WTTEEQLLAVQAIR.K sp|Q9UKL0|RCOR1_HUMAN 1 1656.8835 -1 60963 19633 2 1656.886659 829.449 REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2 4.53 3679 - 0 - - - 1.8939 - 1.42 0.291 - 84.1 1 2 0 0.0031 14 0 0 0 0.00E+00 0.00E+00 - - - 2.0693 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.19635.19635.2 0.705 14-Jul R.EMVLEIIR.E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1001.558 1.71 60965 19635 2 1001.559092 501.7863 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3679.1 - 432949 - - - 1.1372 - 1.756 0.147 - 237.4 1 2 0 0.0011 8 0 0 0 1.51E+07 8.83E+06 - - - 1.8245 0.9005 230117_WJC_METTL3_WT_vs_EV_F07.19637.19637.2 0.637 26-Jun K.VVIGMDVAASEFYR[166.11].N "sp|P13929|ENOB_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN" 2 1565.7787 1.89 60967 19637 2 1565.783284 783.8966 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.37 3679.3 - 351290 - - - 2.9053 - 1.016 0.028 - 71.6 1 2 0 0.0045 14 0 0 0 1.51E+07 7.98E+06 - - - -0.7138 1 230117_WJC_METTL3_WT_vs_EV_F07.19641.19641.2 1.23E-07 13/22 K.QVVPFVYQTIVK.D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1419.8126 1.71 60971 19641 2 1419.814565 710.9136 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 3679.8 - 184703 - - - 1.3924 - 2.48 0.57 - 582.7 1 2 0 0.002 12 0 0 0 4.75E+06 2.78E+06 - - - 5.6402 0.8768 230117_WJC_METTL3_WT_vs_EV_F07.19650.19650.2 4.75 18-May R.AQADEVLQLR.E "sp|O60437|PEPL_HUMAN,tr|K7EKI8|K7EKI8_HUMAN,tr|K7EQ71|K7EQ71_HUMAN" 3 1141.6091 3.58 60979 19650 2 1141.613352 571.8118 Periplakin OS=Homo sapiens OX=9606 GN=PPL PE=1 SV=4 4.37 3681.1 - 1.76E+06 - - - 3.6922 - 1.229 0.04 - 60.1 11 2 0 0.0042 10 0 0 0 1.04E+07 2.90E+06 - - - -0.5545 1 230117_WJC_METTL3_WT_vs_EV_F07.19653.19653.2 1.39E-07 17/26 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 3.42 60982 19653 2 1541.848822 771.9299 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3681.4 - 734964 - - - 2.2557 - 2.953 0.428 - 1075.1 1 2 0 0.0035 14 0 0 0 1.12E+08 3.28E+07 - - - 4.9184 1 230117_WJC_METTL3_WT_vs_EV_F07.19654.19654.2 0.000184 22-Dec R.LLTWVIGTGSPR[166.11].L sp|Q92616|GCN1_HUMAN 1 1308.7429 1.26 60983 19654 2 1308.749748 655.3787 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.75 3681.6 - 687200 - - - 5.2004 - 2.465 0.506 - 543.3 1 2 0 0.0068 12 0 0 0 2.11E+06 1.68E+06 - - - 5.15 1 230117_WJC_METTL3_WT_vs_EV_F07.19660.19660.2 1.22E-05 15/28 R.VGPDVVTDPAFLVTR.S sp|Q9NV31|IMP3_HUMAN 1 1584.8512 1.45 60989 19660 2 1584.852454 793.4329 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3682.4 - 341654 - - - 0.8177 - 2.457 0.526 - 468.5 1 2 0 0.0013 15 0 0 0 4.29E+06 2.97E+06 - - - 5.1357 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19661.19661.2 1.77E-05 13/28 R.VGPDVVTDPAFLVTR[166.11].S sp|Q9NV31|IMP3_HUMAN 1 1594.8594 1.45 60990 19661 2 1594.85976 798.437 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3682.5 - 338758 - - - 0.2082 - 1.898 0.472 - 376.4 1 2 0 0.0003 15 0 0 0 4.29E+06 2.97E+06 - - - 4.1025 1 230117_WJC_METTL3_WT_vs_EV_F07.19662.19662.2 6.34E-09 24-Nov K.LVDSMGWELASVR.R "sp|O94761|RECQ4_HUMAN,tr|A0A087WTJ0|A0A087WTJ0_HUMAN,tr|A0A087X072|A0A087X072_HUMAN" 3 1461.7286 -1 60991 19662 2 1461.737305 731.8716 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.37 3682.6 - 328491 - - - 5.9553 - 2.194 0.604 - 389.9 1 2 0 0.0087 13 0 0 0 0.00E+00 0.00E+00 - - - 5.516 1 230117_WJC_METTL3_WT_vs_EV_F07.19663.19663.2 2.93E-09 14/24 K.LVDSMGWELASVR[166.11].R "sp|O94761|RECQ4_HUMAN,tr|A0A087WTJ0|A0A087WTJ0_HUMAN,tr|A0A087X072|A0A087X072_HUMAN" 3 1471.7369 -1 60992 19663 2 1471.734333 736.8757 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.37 3682.7 - 261368 - - - -1.7238 - 2.902 0.607 - 746.6 1 2 0 -0.0025 13 0 0 0 0.00E+00 0.00E+00 - - - 6.2579 0.9927 230117_WJC_METTL3_WT_vs_EV_F07.19665.19665.2 0.463 14-Aug K.IPEFIAFR.N sp|Q14CX7|NAA25_HUMAN 1 991.5491 0.08 60994 19665 2 991.552496 496.7818 "N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA25 PE=1 SV=1" 6 3683 - 214806 - - - 3.4229 - 1.413 0.173 - 158.5 1 2 0 0.0034 8 0 0 0 1.59E+06 1.99E+07 - - - 1.3604 0.9914 230117_WJC_METTL3_WT_vs_EV_F07.19666.19666.2 0.728 12-Jul R.GQILWFR.G "sp|Q01814|AT2B2_HUMAN,sp|P20020|AT2B1_HUMAN,sp|Q16720|AT2B3_HUMAN,sp|P23634|AT2B4_HUMAN,tr|E7ERY9|E7ERY9_HUMAN,tr|A0A2R8Y4R4|A0A2R8Y4R4_HUMAN,tr|A0A2U3TZI3|A0A2U3TZI3_HUMAN,tr|H0YDG5|H0YDG5_HUMAN,tr|H7BY13|H7BY13_HUMAN,tr|A0A2U3U055|A0A2U3U055_HUMAN,tr|A0A0U1RQU3|A0A0U1RQU3_HUMAN,tr|H7BZS8|H7BZS8_HUMAN,tr|H0YHH6|H0YHH6_HUMAN" 13 918.5076 0.87 60995 19666 2 918.510559 460.2611 Plasma membrane calcium-transporting ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2B2 PE=1 SV=2 9.75 3683.1 - 196044 - - - 3.252 - 1.413 0.136 - 174.5 1 2 0 0.003 7 0 0 0 1.25E+06 1.43E+06 - - - 1.14 1 230117_WJC_METTL3_WT_vs_EV_F07.19667.19667.2 1.36E-06 20-Dec K.IDAELVLPTIR.S "sp|O95985|TOP3B_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 2 1238.7234 1.15 60996 19667 2 1238.732236 620.369 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 4.37 3683.3 - 134477 - - - 7.1025 - 2.539 0.468 - 439.1 1 2 0 0.0088 11 0 0 0 2.00E+06 1.74E+06 - - - 5.0155 0.9466 230117_WJC_METTL3_WT_vs_EV_F07.19671.19671.2 3 14-May R.VPGTLLPR[166.11].L sp|Q96BJ3|AIDA_HUMAN 1 861.5312 1.25 60999 19671 2 861.532333 431.7729 "Axin interactor, dorsalization-associated protein OS=Homo sapiens OX=9606 GN=AIDA PE=1 SV=1" 9.72 3683.7 - 2.17E+06 - - - 1.3639 - 0.847 0.111 - 121.4 1 2 0 0.0012 8 0 0 0 2.11E+07 1.69E+07 - - - -0.6403 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.19677.19677.2 0.253 18-Oct R.AEVVSLLLDR[166.11].K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1123.6476 1.31 61005 19677 2 1123.649691 562.8311 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3684.1 - 637241 - - - 1.8217 - 1.979 0.26 - 439.6 1 2 0 0.002 10 0 0 0 3.36E+07 2.57E+07 - - - 2.866 1 230117_WJC_METTL3_WT_vs_EV_F07.19684.19684.3 5.16E-07 17/52 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 3.94 61012 19684 3 1541.848918 514.9557 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3685 - 255560 - - - 2.318 - 2.689 0.515 - 251.1 1 2 0 0.0036 14 0 0 0 1.29E+07 3.27E+06 - - - 6.9095 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19687.19687.2 5.04E-05 20-Nov R.LLESLDQLELR[166.11].V sp|O95816|BAG2_HUMAN 1 1337.743 8.82 61015 19687 2 1337.746712 669.8788 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.14 3685.4 - 157595 - - - 2.7741 - 2.298 0.445 - 375.1 1 2 0 0.0037 11 0 0 0 2.25E+08 2.55E+07 - - - 4.5775 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19690.19690.2 0.00192 18-Oct K.IELFADVVPK.T "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 1129.6383 1.22 61017 19690 2 1129.639805 565.8264 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.37 3685.8 - 6.90E+06 - - - 1.3225 - 2.207 0.417 - 278 1 2 0 0.0015 10 0 0 0 5.60E+07 4.60E+07 - - - 4.3302 1 230117_WJC_METTL3_WT_vs_EV_F07.19691.19691.2 0.000286 18-Nov R.AEVVSLLLDR.K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1113.6394 1.32 61018 19691 2 1113.642013 557.827 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3685.8 - 5.50E+06 - - - 2.3697 - 2.37 0.519 - 545.7 1 2 0 0.0026 10 0 0 0 3.38E+07 2.57E+07 - - - 5.2821 1 230117_WJC_METTL3_WT_vs_EV_F07.19692.19692.2 4.13E-05 26-Nov K.LLDAVDTYIPVPAR[166.11].D sp|P49411|EFTU_HUMAN 1 1551.8536 3.42 61019 19692 2 1551.855827 776.9341 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3685.8 - 3.09E+06 - - - 1.426 - 2.492 0.56 - 431.3 1 2 0 0.0022 14 0 0 0 1.12E+08 3.28E+07 - - - 5.4678 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.19693.19693.2 1.31 18-Aug K.IELFADVVPK[136.11].T "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 1137.6525 1.21 61020 19693 2 1137.65521 569.8335 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.37 3685.9 - 2.72E+06 - - - 2.3724 - 1.56 0.2 - 119.8 1 2 0 0.0027 10 0 0 0 5.59E+07 4.62E+07 - - - 1.7586 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19694.19694.2 0.00368 16-Sep K.TFDPYIIIR[166.11].A sp|Q13601|KRR1_HUMAN 1 1146.6313 0.46 61021 19694 2 1146.633917 574.3229 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 5.5 3685.9 - 1.90E+06 - - - 2.312 - 1.696 0.308 - 263.7 1 2 0 0.0027 9 0 0 0 6.95E+06 1.51E+07 - - - 2.8434 0.9778 230117_WJC_METTL3_WT_vs_EV_F07.19699.19699.2 1.93 12-Jun R.AFLPLLK.A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 800.516 1.34 61026 19699 2 800.515987 401.2653 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3686.4 - 978121 - - - -0.03 - 1.171 0.089 - 197.1 1 2 0 0 7 0 0 0 2.06E+07 1.54E+07 - - - 0.1985 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19700.19700.2 0.0261 13/20 R.VLITTLITAGR.L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1156.718 1.13 61027 19700 2 1156.720523 579.3663 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3686.5 - 884639 - - - 2.2166 - 2.46 0.353 - 623.2 1 2 0 0.0026 11 0 0 0 7.35E+06 6.50E+06 - - - 4.0826 1 230117_WJC_METTL3_WT_vs_EV_F07.19704.19704.2 0.0016 20-Dec R.VLITTLITAGR[166.11].L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1166.7262 1.13 61031 19704 2 1166.728901 584.3704 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3687 - 716061 - - - 2.2902 - 2.478 0.448 - 458.3 1 2 0 0.0027 11 0 0 0 7.35E+06 6.50E+06 - - - 4.804 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19706.19706.2 0.000879 20-Sep K.VAPGFQFFATR.R sp|Q9NU22|MDN1_HUMAN 1 1239.64 0.85 61033 19706 2 1239.641303 620.8273 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 9.72 3687.2 - 521651 - - - 1.0164 - 1.766 0.333 - 216.6 1 2 0 0.0013 11 0 0 0 4.56E+06 5.33E+06 - - - 3.0387 1 230117_WJC_METTL3_WT_vs_EV_F07.19707.19707.2 6.26E-08 14/26 R.LIVVLEGASLETVK.V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1469.8705 1.16 61034 19707 2 1469.875524 735.9425 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3687.3 - 300390 - - - 3.4207 - 2.963 0.49 - 579.2 1 2 0 0.005 14 0 0 0 2.37E+06 2.05E+06 - - - 5.3843 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19713.19713.2 0.0168 18-Sep R.EALLAALGYK[136.11].N sp|Q9BU76|MMTA2_HUMAN 1 1055.6106 0.61 61039 19713 2 1055.612223 528.8126 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3687.9 - 5.68E+06 - - - 1.493 - 2.151 0.268 - 248.5 1 2 0 0.0016 10 0 0 0 2.71E+07 4.46E+07 - - - 3.1579 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19714.19714.2 0.116 18-Sep R.EALLAALGYK.N sp|Q9BU76|MMTA2_HUMAN 1 1047.5964 0.69 61040 19714 2 1047.598078 524.8055 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3687.9 - 5.04E+06 - - - 1.5569 - 2.169 0.304 - 223.2 1 2 0 0.0016 10 0 0 0 2.71E+07 3.94E+07 - - - 3.447 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19721.19721.2 0.000182 16-Sep K.GLMVLELPK.R "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 998.5834 3.93 61047 19721 2 998.585007 500.299 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6 3688.7 - 1.48E+06 - - - 1.5702 - 1.748 0.418 - 246.9 1 2 0 0.0016 9 0 0 0 3.71E+06 9.44E+05 - - - 3.7435 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19722.19722.2 0.00183 22-Nov R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.28 61048 19722 2 1315.787959 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3688.8 - 1.36E+06 - - - 1.2054 - 1.986 0.394 - 347.3 1 2 0 0.0016 12 0 0 0 4.56E+06 3.56E+06 - - - 3.7559 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19724.19724.2 0.00129 22-Oct R.SQPAILLLTAAR.D "sp|Q5JTV8|TOIP1_HUMAN,tr|H0Y4R4|H0Y4R4_HUMAN,tr|J3KN66|J3KN66_HUMAN,tr|A0A0A0MSK5|A0A0A0MSK5_HUMAN" 4 1252.7503 1.85 61050 19724 2 1252.753559 627.3824 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=2 9.47 3689 - 1.00E+06 - - - 2.5839 - 2.121 0.416 - 347.5 1 2 0 0.0032 12 0 0 0 4.12E+06 2.22E+06 - - - 4.0909 0.9882 230117_WJC_METTL3_WT_vs_EV_F07.19725.19725.2 0.553 24-Jul R.TLGLC[160.03]GTFNGNIR.D "sp|Q3ZCN5|OTOGL_HUMAN,tr|A0A2R8YF04|A0A2R8YF04_HUMAN" 2 1421.7085 68.82 61051 19725 2 1421.712093 711.8615 Otogelin-like protein OS=Homo sapiens OX=9606 GN=OTOGL PE=1 SV=5 7.91 3689.1 - 989261 - - - 2.504 - 1.317 0.113 - 97.5 1 2 0 0.0036 13 0 0 0 3.35E+06 4.87E+04 - - - 0.5812 1 230117_WJC_METTL3_WT_vs_EV_F07.19727.19727.2 0.000177 13/26 R.LIVVLEGASLETVK[136.11].V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1477.8847 1.16 61053 19727 2 1477.886951 739.9496 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3689.4 - 979234 - - - 1.5258 - 2.761 0.482 - 516.2 1 2 0 0.0023 14 0 0 0 2.37E+06 2.05E+06 - - - 5.1489 1 230117_WJC_METTL3_WT_vs_EV_F07.19728.19728.2 4.08E-07 22-Dec K.FATEDEAWAFVR.K sp|O60930|RNH1_HUMAN 1 1440.6674 0.37 61054 19728 2 1440.672669 721.341 Ribonuclease H1 OS=Homo sapiens OX=9606 GN=RNASEH1 PE=1 SV=2 4.14 3689.5 - 814959 - - - 3.6712 - 2.521 0.524 - 436.1 1 2 0 0.0053 12 0 0 0 1.97E+06 5.37E+06 - - - 5.3425 1 230117_WJC_METTL3_WT_vs_EV_F07.19740.19740.2 0.00157 22-Dec K.VIHDNFGIVEGL.M "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1311.6823 - 61065 19740 2 1311.68516 656.8484 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.35 3690.9 - 238026 - - - 2.1789 - 2.495 0.483 - 541.1 1 1 0 0.0029 12 0 0 0 - - - - - 5.0132 0.992 230117_WJC_METTL3_WT_vs_EV_F07.19746.19746.2 5.3 12-Jun R.EIFDLIR.S "sp|Q9Y3D0|CIA2B_HUMAN,tr|H3BNV7|H3BNV7_HUMAN,tr|J3KS95|J3KS95_HUMAN" 3 904.5018 2.92 61070 19746 2 904.50299 453.2582 Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1 4.37 3691.6 - 1.97E+06 - - - 1.2957 - 1.305 0.101 - 207 1 2 0 0.0012 7 0 0 0 3.43E+07 1.17E+07 - - - 0.6301 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19748.19748.2 0.0003 13/18 R.IINDLLQSLR.S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1183.6925 2.11 61071 19748 2 1183.694206 592.8535 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3691.8 - 2.80E+06 - - - 1.4649 - 2.432 0.152 - 551.6 1 2 0 0.0017 10 0 0 0 1.45E+08 6.89E+07 - - - 2.6438 0.9857 230117_WJC_METTL3_WT_vs_EV_F07.19750.19750.2 1.75 12-Jun R.AFLPLLK[136.11].A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 808.5302 1.34 61073 19750 2 808.530736 405.2724 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3691.9 - 2.12E+06 - - - 0.6493 - 1.246 0.076 - 189.6 1 2 0 0.0005 7 0 0 0 2.06E+07 1.54E+07 - - - 0.2991 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19752.19752.2 0.00142 14-Aug R.YELALILK.A sp|P82932|RT06_HUMAN 1 961.5848 2.42 61075 19752 2 961.585827 481.7997 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3692.1 - 1.56E+06 - - - 1.0483 - 1.548 0.429 - 179.7 1 2 0 0.001 8 0 0 0 1.26E+07 5.22E+06 - - - 3.5271 1 230117_WJC_METTL3_WT_vs_EV_F07.19754.19754.2 4.53E-07 18-Nov K.LFGYEMAEFK[136.11].V sp|Q9UKD2|MRT4_HUMAN 1 1241.5882 0.89 61077 19754 2 1241.592425 621.8014 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 4.53 3692.2 - 966936 - - - 3.4053 - 1.857 0.536 - 330.2 1 2 0 0.0042 10 0 0 0 4.63E+06 5.23E+06 - - - 4.7263 0.9905 230117_WJC_METTL3_WT_vs_EV_F07.19755.19755.2 1.89 14-Jun R.YELALILK[136.11].A sp|P82932|RT06_HUMAN 1 969.599 2.42 61078 19755 2 969.599011 485.8068 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3692.3 - 716637 - - - -0.0083 - 1.281 0.172 - 90.4 4 2 0 0 8 0 0 0 1.26E+07 5.22E+06 - - - 0.7893 1 230117_WJC_METTL3_WT_vs_EV_F07.19756.19756.2 6.25E-06 14/22 R.IEGVLLLGEPVR.W "sp|Q9BXW7|HDHD5_HUMAN,tr|A8MYZ9|A8MYZ9_HUMAN" 2 1293.7656 2.54 61079 19756 2 1293.76553 647.8901 Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Homo sapiens OX=9606 GN=HDHD5 PE=1 SV=1 4.53 3692.4 - 618808 - - - -0.0827 - 2.98 0.47 - 1061.9 1 2 0 -0.0001 12 0 0 0 5.69E+06 2.24E+06 - - - 5.3854 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19758.19758.2 0.071 13/20 R.LALVISELEGK[136.11].A "sp|Q12899|TRI26_HUMAN,tr|A2AE48|A2AE48_HUMAN" 2 1178.7002 1.21 61081 19758 2 1178.702758 590.3574 Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1 4.53 3692.6 - 523227 - - - 2.1787 - 2.554 0.29 - 521.1 1 2 0 0.0026 11 0 0 0 6.00E+06 4.97E+06 - - - 3.7187 0.9942 230117_WJC_METTL3_WT_vs_EV_F07.19760.19760.2 0.394 14-Jun K.VLIVVPFR[166.11].E "sp|Q68CQ4|UTP25_HUMAN,tr|H7C2R4|H7C2R4_HUMAN" 2 951.6145 1.71 61083 19760 2 951.616134 476.8145 U3 small nucleolar RNA-associated protein 25 homolog OS=Homo sapiens OX=9606 GN=UTP25 PE=1 SV=2 9.72 3692.9 - 425613 - - - 1.7244 - 1.149 0.193 - 72.5 1 2 0 0.0016 8 0 0 0 2.31E+06 1.35E+06 - - - 0.8849 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.19768.19768.2 1.05 18-Nov R.IINDLLQSLR[166.11].S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1193.7007 2.11 61089 19768 2 1193.703001 597.8576 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3693.8 - 6.90E+06 - - - 1.8924 - 2.246 0.169 - 316.7 1 2 0 0.0023 10 0 0 0 1.45E+08 6.89E+07 - - - 2.5471 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.19772.19772.2 0.0293 12-Jun R.EAYFWLR.Q sp|Q8TCJ2|STT3B_HUMAN 1 983.4865 1.14 61093 19772 2 983.488441 492.7505 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1 6.1 3694.2 - 495075 - - - 1.9716 - 1.307 0.321 - 152.7 1 2 0 0.0019 7 0 0 0 5.20E+06 4.58E+06 - - - 2.2596 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19774.19774.2 0.000613 12-Jul R.EAYFWLR[166.11].Q sp|Q8TCJ2|STT3B_HUMAN 1 993.4948 1.1 61095 19774 2 993.496106 497.7547 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1 6.1 3694.4 - 388970 - - - 1.3427 - 1.656 0.372 - 237.5 1 2 0 0.0013 7 0 0 0 4.88E+06 4.44E+06 - - - 3.3864 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.19776.19776.2 0.000383 16-Sep R.GWAPVFLDR[166.11].E "sp|Q9Y5Y2|NUBP2_HUMAN,tr|H3BQR2|H3BQR2_HUMAN,tr|H3BRE1|H3BRE1_HUMAN,tr|H3BNF0|H3BNF0_HUMAN,tr|H3BNS4|H3BNS4_HUMAN" 5 1069.5584 3.34 61097 19776 2 1069.561804 535.7865 Cytosolic Fe-S cluster assembly factor NUBP2 OS=Homo sapiens OX=9606 GN=NUBP2 PE=1 SV=1 5.84 3694.7 - 264075 - - - 3.1499 - 1.755 0.41 - 269.1 1 2 0 0.0034 9 0 0 0 9.80E+06 2.94E+06 - - - 3.6955 0.9808 230117_WJC_METTL3_WT_vs_EV_F07.19778.19778.2 0.000691 14-Oct R.NYFGLFPR[166.11].V sp|Q8WUF5|IASPP_HUMAN 1 1022.5213 1.72 61099 19778 2 1022.517342 512.2679 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.75 3694.9 - 191568 - - - -3.8914 - 1.358 0.307 - 315.2 1 2 0 -0.004 8 0 0 0 1.43E+07 8.27E+06 - - - 2.2302 1 230117_WJC_METTL3_WT_vs_EV_F07.19779.19779.2 2.18E-09 14/26 K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 2.47 61100 19779 2 1772.805516 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3695.1 - 167770 - - - 1.2105 - 2.61 0.665 - 754.4 1 2 0 0.0021 14 0 0 0 5.67E+06 2.29E+06 - - - 6.3595 1 230117_WJC_METTL3_WT_vs_EV_F07.19786.19786.2 0.000534 18-Nov R.LGLEDFESLK[136.11].V sp|Q15208|STK38_HUMAN 1 1157.606 0.57 61105 19786 2 1157.60691 579.8103 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3695.9 - 1.31E+06 - - - 0.825 - 2.316 0.473 - 279.4 1 2 0 0.001 10 0 0 0 1.88E+08 3.30E+08 - - - 4.8785 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19788.19788.2 7.05E-05 18-Oct R.TALYNYIFAK.K "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1202.6336 7.89 61107 19788 2 1202.634179 602.3241 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 8.17 3696.1 - 1.09E+06 - - - 0.5147 - 2.105 0.453 - 302.2 1 2 0 0.0006 10 0 0 0 6.12E+06 7.76E+05 - - - 4.4643 1 230117_WJC_METTL3_WT_vs_EV_F07.19794.19794.2 6.64E-05 22-Dec Y.AIYELAVASFPK[136.11].K "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6R9C3|D6R9C3_HUMAN" 4 1315.7267 2.04 61113 19794 2 1315.727737 658.8706 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 6.05 3696.8 - 246741 - - - 0.7585 - 2.398 0.453 - 383.8 1 1 0 0.001 12 0 0 0 4.78E+06 2.34E+06 - - - 4.6879 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19798.19798.2 0.0423 14-Jul R.LLFFAPTR.R sp|Q07820|MCL1_HUMAN 1 963.5542 3.98 61115 19798 2 963.555201 482.7844 Induced myeloid leukemia cell differentiation protein Mcl-1 OS=Homo sapiens OX=9606 GN=MCL1 PE=1 SV=3 9.75 3697.3 - 936193 - - - 1.0513 - 1.629 0.336 - 180.2 1 2 0 0.001 8 0 0 0 9.38E+06 2.36E+06 - - - 2.9941 1 230117_WJC_METTL3_WT_vs_EV_F07.19799.19799.2 0.000267 18-Sep R.LGLEDFESLK.V sp|Q15208|STK38_HUMAN 1 1149.5918 0.57 61116 19799 2 1149.591769 575.8032 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3697.3 - 2.56E+06 - - - 0.0122 - 2.138 0.482 - 177.9 1 2 0 0 10 0 0 0 1.88E+08 3.30E+08 - - - 4.7221 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19800.19800.2 0.0198 18-Sep R.IEGLLAAFPK[136.11].L "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|E9PK34|E9PK34_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 4 1065.6314 2.25 61117 19800 2 1065.633217 533.823 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6 3697.4 - 1.08E+06 - - - 1.722 - 1.986 0.309 - 145.5 1 2 0 0.0018 10 0 0 0 2.74E+07 1.22E+07 - - - 3.2379 0.9948 230117_WJC_METTL3_WT_vs_EV_F07.19803.19803.2 0.00951 16-Aug K.LQLSLADFR[166.11].R "sp|O00541|PESC_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 2 1071.5952 1 61120 19803 2 1071.600299 536.8049 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 5.84 3697.6 - 853013 - - - 4.7443 - 1.599 0.288 - 190.2 1 2 0 0.0051 9 0 0 0 1.56E+07 1.57E+07 - - - 2.5245 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19808.19808.2 0.081 13/24 R.LENLGIPEEELLR.Q sp|Q01658|NC2B_HUMAN 1 1523.8195 3.36 61125 19808 2 1523.821996 762.917 Protein Dr1 OS=Homo sapiens OX=9606 GN=DR1 PE=1 SV=1 4.09 3698.3 - 194176 - - - 1.6229 - 2.523 0.312 - 483.9 1 2 0 0.0025 13 0 0 0 2.70E+06 8.03E+05 - - - 3.7198 0.9956 230117_WJC_METTL3_WT_vs_EV_F07.19811.19811.2 5.16E-05 16-Sep K.GLFEVNPWK[136.11].R "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1096.5797 3.62 61126 19811 2 1096.585009 549.2971 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 6 3698.7 - 955818 - - - 4.8587 - 1.77 0.283 - 268 1 2 0 0.0053 9 0 0 0 4.04E+07 1.12E+07 - - - 2.7814 0.9942 230117_WJC_METTL3_WT_vs_EV_F07.19812.19812.2 0.051 14-Sep K.VAIIIPFR[166.11].N "sp|P15291|B4GT1_HUMAN,sp|O43286|B4GT5_HUMAN,tr|Q86XA6|Q86XA6_HUMAN" 3 937.5988 0.2 61127 19812 2 937.604107 469.8067 "Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5" 9.72 3698.8 - 750096 - - - 5.6143 - 1.961 0.274 - 319.4 1 2 0 0.0053 8 0 0 0 7.60E+06 3.87E+07 - - - 3.0942 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.19813.19813.2 0.374 14-Aug K.VAIIIPFR.N "sp|P15291|B4GT1_HUMAN,sp|O43286|B4GT5_HUMAN,tr|Q86XA6|Q86XA6_HUMAN" 3 927.5906 0.44 61128 19813 2 927.592595 464.8026 "Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5" 9.72 3699 - 542813 - - - 2.1798 - 1.886 0.209 - 250.9 1 2 0 0.002 8 0 0 0 7.60E+06 1.73E+07 - - - 2.4975 0.9718 230117_WJC_METTL3_WT_vs_EV_F07.19816.19816.2 0.0245 18-Nov R.TEVVSLLLDR.K "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1143.6499 2.35 61131 19816 2 1143.660281 572.8322 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 3699.4 - 365796 - - - 9.043 - 1.945 0.308 - 310 1 2 0 0.0103 10 0 0 0 1.20E+07 5.11E+06 - - - 3.1696 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19819.19819.3 0.00186 Dec-40 R.MLIPYIEHWPR.A "sp|O75208|COQ9_HUMAN,tr|H3BPY0|H3BPY0_HUMAN,tr|H3BNT2|H3BNT2_HUMAN" 3 1453.754 3.53 61134 19819 3 1453.759765 485.592 "Ubiquinone biosynthesis protein COQ9, mitochondrial OS=Homo sapiens OX=9606 GN=COQ9 PE=1 SV=1" 6.5 3699.7 - 245822 - - - 3.947 - 2.677 0.374 - 256.3 1 2 0 0.0057 11 0 0 0 2.99E+06 8.48E+05 - - - 5.5055 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19820.19820.2 2.63E-05 26-Sep K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 2.47 61135 19820 2 1762.800068 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3699.9 - 227028 - - - 2.8183 - 1.631 0.457 - 139.4 1 2 0 0.005 14 0 0 0 5.67E+06 2.29E+06 - - - 3.6424 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.19833.19833.2 0.0914 12-Sep K.NFGIWLR[166.11].Y "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 914.5002 0.86 61146 19833 2 914.501882 458.2574 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 9.75 3701.5 - 3.38E+06 - - - 1.848 - 1.702 0.257 - 470.8 1 2 0 0.0017 7 0 0 0 1.23E+08 1.43E+08 - - - 2.6237 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19834.19834.2 0.0132 16-Oct K.LQLSLADFR.R "sp|O00541|PESC_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 2 1061.5869 1 61147 19834 2 1061.589595 531.8007 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 5.84 3701.6 - 1.98E+06 - - - 2.4963 - 2.013 0.36 - 360.7 1 2 0 0.0027 9 0 0 0 1.56E+07 1.57E+07 - - - 3.7232 0.8686 230117_WJC_METTL3_WT_vs_EV_F07.19836.19836.2 0.145 14-Sep L.IALALLAR.R sp|P43116|PE2R2_HUMAN 1 839.5593 999 61149 19836 2 839.56054 420.7869 Prostaglandin E2 receptor EP2 subtype OS=Homo sapiens OX=9606 GN=PTGER2 PE=1 SV=2 9.75 3701.9 - 1.08E+06 - - - 1.5091 - 1.841 0.12 - 361.1 1 1 0 0.0013 8 0 0 0 5.84E+06 0.00E+00 - - - 1.7676 0.9956 230117_WJC_METTL3_WT_vs_EV_F07.19837.19837.2 0.219 12-Jul K.LTFLDLR.N "sp|Q9H9A6|LRC40_HUMAN,tr|X6R5P2|X6R5P2_HUMAN" 2 876.5069 1.39 61150 19837 2 876.508092 439.2607 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.84 3702 - 972279 - - - 1.3565 - 1.52 0.096 - 218 1 2 0 0.0012 7 0 0 0 6.10E+06 4.40E+06 - - - 1.0764 0.9921 230117_WJC_METTL3_WT_vs_EV_F07.19838.19838.2 0.0875 12-Jun K.LTFLDLR[166.11].N "sp|Q9H9A6|LRC40_HUMAN,tr|X6R5P2|X6R5P2_HUMAN" 2 886.5152 1.39 61151 19838 2 886.51646 444.2649 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.84 3702.1 - 629095 - - - 1.4518 - 1.497 0.062 - 158.6 2 2 0 0.0013 7 0 0 0 6.10E+06 4.40E+06 - - - 0.6425 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19841.19841.2 2.30E-05 22-Nov K.QYPISLVLAPTR.E "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1356.7765 0.81 61154 19841 2 1356.775748 679.3955 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.75 3702.5 - 254416 - - - -0.5808 - 1.935 0.449 - 437.9 1 2 0 -0.0008 12 0 0 0 1.16E+06 1.44E+06 - - - 4.0939 0.998 230117_WJC_METTL3_WT_vs_EV_F07.19842.19842.2 0.00897 14-Oct K.SVWALLQR[166.11].N sp|Q5VUD6|DIK1B_HUMAN 1 981.5635 2.58 61155 19842 2 981.566936 491.789 Divergent protein kinase domain 1B OS=Homo sapiens OX=9606 GN=DIPK1B PE=1 SV=3 9.47 3702.6 - 235243 - - - 3.4802 - 1.776 0.246 - 324.7 1 2 0 0.0034 8 0 0 0 3.66E+06 1.42E+06 - - - 2.5891 0.9892 230117_WJC_METTL3_WT_vs_EV_F07.19843.19843.2 0.000662 24-Nov R.LENLGIPEEELLR[166.11].Q sp|Q01658|NC2B_HUMAN 1 1533.8278 3.16 61156 19843 2 1533.839496 767.9212 Protein Dr1 OS=Homo sapiens OX=9606 GN=DR1 PE=1 SV=1 4.09 3702.8 - 146618 - - - 7.6299 - 2.297 0.4 - 306.9 1 2 0 0.0117 13 0 0 0 2.54E+06 8.03E+05 - - - 4.1261 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.19844.19844.2 0.000421 22-Oct R.LLSAGQLLFQGR[166.11].A sp|Q567V2|M17L2_HUMAN 1 1311.7538 -1 61157 19844 2 1311.752131 656.8842 Mpv17-like protein 2 OS=Homo sapiens OX=9606 GN=MPV17L2 PE=1 SV=2 9.75 3702.9 - 143502 - - - -1.3036 - 2.084 0.321 - 201.8 1 2 0 -0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 3.3434 1 230117_WJC_METTL3_WT_vs_EV_F07.19848.19848.3 5.08E-09 25/68 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 2.81 61159 19848 3 1918.06273 640.3618 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3703.4 - 1.25E+06 - - - -0.4588 - 3.878 0.571 - 689.5 1 2 0 -0.0009 18 0 0 0 2.16E+07 7.68E+06 - - - 8.2807 1 230117_WJC_METTL3_WT_vs_EV_F07.19850.19850.2 0.000129 18-Nov K.VAEITELILK[136.11].A "sp|Q06265|EXOS9_HUMAN,tr|D6R905|D6R905_HUMAN,tr|H0Y9L5|H0Y9L5_HUMAN,tr|D6RIY6|D6RIY6_HUMAN" 4 1135.6944 1.17 61161 19850 2 1135.699328 568.8545 Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3 4.53 3703.6 - 2.87E+06 - - - 4.3603 - 2.31 0.443 - 471.2 1 2 0 0.005 10 0 0 0 1.80E+07 1.54E+07 - - - 4.6485 1 230117_WJC_METTL3_WT_vs_EV_F07.19851.19851.2 2.09E-08 16/22 R.LPADTC[160.03]LLEFAR.L "sp|Q8NF37|PCAT1_HUMAN,tr|A0A0G2JQ62|A0A0G2JQ62_HUMAN,tr|A0A0G2JRI7|A0A0G2JRI7_HUMAN" 3 1404.7071 2.24 61162 19851 2 1404.708759 703.3608 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 4.37 3703.7 - 1.00E+06 - - - 1.1554 - 2.859 0.634 - 1162.5 1 2 0 0.0016 12 0 0 0 6.37E+06 2.84E+06 - - - 6.4872 0.9705 230117_WJC_METTL3_WT_vs_EV_F07.19852.19852.2 0.788 14-Sep R.NLFEQLVR[166.11].R "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VV47|F8VV47_HUMAN,tr|F8VUW9|F8VUW9_HUMAN,tr|F8VWY4|F8VWY4_HUMAN,tr|F8VRD2|F8VRD2_HUMAN,tr|F8VVY0|F8VVY0_HUMAN,tr|F8VZ66|F8VZ66_HUMAN,tr|F8VWX0|F8VWX0_HUMAN,tr|F8VS54|F8VS54_HUMAN,tr|F8W0L1|F8W0L1_HUMAN,tr|F8VVE5|F8VVE5_HUMAN,tr|F8VV39|F8VV39_HUMAN,tr|F8VXH1|F8VXH1_HUMAN" 13 1027.569 2.55 61163 19852 2 1027.574036 514.7918 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 6 3703.9 - 906348 - - - 4.9009 - 1.382 0.138 - 244 1 2 0 0.005 8 0 0 0 1.15E+07 4.52E+06 - - - 1.0344 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.19853.19853.2 0.00404 16-Jul K.STLINTLFK.S "sp|Q9UHD8|SEPT9_HUMAN,tr|K7EKN4|K7EKN4_HUMAN,tr|K7EN52|K7EN52_HUMAN,tr|K7EQD7|K7EQD7_HUMAN,tr|K7ER52|K7ER52_HUMAN,tr|A0A6Q8PHC2|A0A6Q8PHC2_HUMAN,tr|K7ER14|K7ER14_HUMAN,tr|K7EIE4|K7EIE4_HUMAN,tr|K7EJZ2|K7EJZ2_HUMAN,tr|K7ENQ5|K7ENQ5_HUMAN,tr|K7EL40|K7EL40_HUMAN,tr|K7EK18|K7EK18_HUMAN" 12 1035.5964 0.85 61164 19853 2 1035.598223 518.8055 Septin-9 OS=Homo sapiens OX=9606 GN=SEPTIN9 PE=1 SV=2 8.47 3704 - 644546 - - - 1.715 - 1.21 0.274 - 103 1 2 0 0.0018 9 0 0 0 2.21E+06 2.61E+06 - - - 1.6157 1 230117_WJC_METTL3_WT_vs_EV_F07.19855.19855.3 3.35E-06 20/68 K.ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1928.0719 2.9 61166 19855 3 1928.073477 643.6979 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3704.2 - 599390 - - - 0.8283 - 3.121 0.479 - 213.7 1 2 0 0.0016 18 0 0 0 2.23E+07 7.68E+06 - - - 6.7141 0.996 230117_WJC_METTL3_WT_vs_EV_F07.19856.19856.2 0.876 14-Aug K.LLILALER[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 949.62 1.43 61167 19856 2 949.622122 475.8173 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6 3704.4 - 519086 - - - 2.263 - 1.617 0.112 - 203.4 1 2 0 0.0021 8 0 0 0 3.69E+07 2.58E+07 - - - 1.3169 0.9959 230117_WJC_METTL3_WT_vs_EV_F07.19857.19857.2 1.01 14-Aug K.SVWALLQR.N sp|Q5VUD6|DIK1B_HUMAN 1 971.5553 2.4 61168 19857 2 971.556602 486.7849 Divergent protein kinase domain 1B OS=Homo sapiens OX=9606 GN=DIPK1B PE=1 SV=3 9.47 3704.5 - 454739 - - - 1.3916 - 1.351 0.16 - 145.3 1 2 0 0.0014 8 0 0 0 4.34E+06 1.81E+06 - - - 1.1297 0.999 230117_WJC_METTL3_WT_vs_EV_F07.19858.19858.2 1.5 14-Aug K.SLLAGLLK[136.11].K "sp|P31751|AKT2_HUMAN,tr|M0R0P9|M0R0P9_HUMAN,tr|J3QKW1|J3QKW1_HUMAN,tr|J3QL45|J3QL45_HUMAN,tr|M0R283|M0R283_HUMAN,tr|M0QZW8|M0QZW8_HUMAN" 6 821.5466 0.72 61169 19858 2 821.548123 411.7806 RAC-beta serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=AKT2 PE=1 SV=2 8.47 3704.6 - 398225 - - - 1.866 - 1.594 0.27 - 200 1 2 0 0.0015 8 0 0 0 2.13E+06 2.97E+06 - - - 2.4409 0.999 230117_WJC_METTL3_WT_vs_EV_F07.19859.19859.2 0.00406 16-Oct R.EEGVLTLWR.G "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 1101.5819 -1 61170 19859 2 1101.583276 551.7982 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 4.53 3704.8 - 387374 - - - 1.2863 - 1.532 0.292 - 213.9 1 2 0 0.0014 9 0 0 0 0.00E+00 0.00E+00 - - - 2.4314 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.19861.19861.2 0.000242 20-Sep K.YFNEFLDGELK.S "sp|O00471|EXOC5_HUMAN,tr|A0A0A0MSI8|A0A0A0MSI8_HUMAN" 2 1373.6503 2.55 61172 19861 2 1373.649896 687.8324 Exocyst complex component 5 OS=Homo sapiens OX=9606 GN=EXOC5 PE=1 SV=1 4.14 3705 - 276582 - - - -0.3181 - 1.738 0.429 - 200.7 1 2 0 -0.0004 11 0 0 0 1.11E+06 4.33E+05 - - - 3.7047 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.19863.19863.2 0.0212 24-Oct K.ALLLVPASVNC[160.03]LR.L sp|Q5SRE5|NU188_HUMAN 1 1424.8174 0.78 61174 19863 2 1424.816708 713.416 Nucleoporin NUP188 OS=Homo sapiens OX=9606 GN=NUP188 PE=1 SV=1 8.29 3705.3 - 231244 - - - -0.4548 - 2.09 0.249 - 281.8 1 2 0 -0.0006 13 0 0 0 1.47E+06 1.88E+06 - - - 2.7719 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19864.19864.2 0.000396 22-Oct R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.27 61175 19864 2 1323.80328 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3705.4 - 218527 - - - 2.0449 - 1.765 0.434 - 262.7 1 2 0 0.0027 12 0 0 0 1.80E+06 1.42E+06 - - - 3.7406 1 230117_WJC_METTL3_WT_vs_EV_F07.19867.19867.2 0.00154 13/20 R.LFEAEAQDLFR[166.11].D sp|Q9H223|EHD4_HUMAN 1 1347.6698 2.42 61178 19867 2 1347.673225 674.8422 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3705.8 - 123681 - - - 2.5147 - 2.646 0.464 - 663.4 1 2 0 0.0034 11 0 0 0 3.08E+07 1.27E+07 - - - 5.0994 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.19870.19870.2 0.00362 18-Jul K.VAEITELILK.A "sp|Q06265|EXOS9_HUMAN,tr|D6R905|D6R905_HUMAN,tr|H0Y9L5|H0Y9L5_HUMAN,tr|D6RIY6|D6RIY6_HUMAN" 4 1127.6802 1.19 61180 19870 2 1127.684376 564.8474 Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3 4.53 3706.1 - 707255 - - - 3.7245 - 1.889 0.372 - 109.4 1 2 0 0.0042 10 0 0 0 1.82E+07 1.53E+07 - - - 3.5627 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19872.19872.2 3.63E-05 18-Oct R.C[160.03]LFQSPLFAK.A sp|Q86X55|CARM1_HUMAN 1 1209.6216 7.04 61182 19872 2 1209.621687 605.8181 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 8.22 3706.2 - 2.04E+06 - - - 0.0587 - 1.649 0.505 - 267.7 1 2 0 0.0001 10 0 0 0 1.03E+07 1.47E+06 - - - 4.167 0.9852 230117_WJC_METTL3_WT_vs_EV_F07.19874.19874.3 6.00E-06 Oct-48 K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 0.59 61184 19874 3 1601.74818 534.5887 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3706.3 - 1.26E+06 - - - 627.127 - 1.974 0.399 - 97.4 1 2 0 1.0039 13 0 0 0 7.22E+06 1.22E+07 - - - 4.5542 1 230117_WJC_METTL3_WT_vs_EV_F07.19875.19875.2 0.00649 20-Nov R.LFEAEAQDLFR.D sp|Q9H223|EHD4_HUMAN 1 1337.6616 2.42 61185 19875 2 1337.662331 669.8381 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3706.4 - 1.20E+06 - - - 0.5719 - 2.452 0.463 - 453.2 1 2 0 0.0008 11 0 0 0 3.08E+07 1.27E+07 - - - 4.8868 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19876.19876.2 0.0327 14-Aug R.NLFEQLVR.R "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VV47|F8VV47_HUMAN,tr|F8VUW9|F8VUW9_HUMAN,tr|F8VWY4|F8VWY4_HUMAN,tr|F8VRD2|F8VRD2_HUMAN,tr|F8VVY0|F8VVY0_HUMAN,tr|F8VZ66|F8VZ66_HUMAN,tr|F8VWX0|F8VWX0_HUMAN,tr|F8VS54|F8VS54_HUMAN,tr|F8W0L1|F8W0L1_HUMAN,tr|F8VVE5|F8VVE5_HUMAN,tr|F8VV39|F8VV39_HUMAN,tr|F8VXH1|F8VXH1_HUMAN" 13 1017.5607 2.35 61186 19876 2 1017.562869 509.7876 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 6 3706.4 - 1.14E+06 - - - 2.1021 - 1.466 0.361 - 265.7 1 2 0 0.0021 8 0 0 0 1.23E+07 5.24E+06 - - - 2.8604 0.9304 230117_WJC_METTL3_WT_vs_EV_F07.19877.19877.2 0.00584 14-Jul F.GPILNFLR.H "sp|Q8N5Z5|KCD17_HUMAN,tr|H7C323|H7C323_HUMAN,tr|B0QYB2|B0QYB2_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 5 928.5494 0.6 61187 19877 2 928.549225 465.282 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 9.75 3706.5 - 710753 - - - -0.2283 - 1.756 0.315 - 223.3 1 1 0 -0.0002 8 0 0 0 1.30E+07 2.15E+07 - - - 3.0656 0.997 230117_WJC_METTL3_WT_vs_EV_F07.19878.19878.2 0.00858 16-Jul K.LFSNVLILK.S "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1045.6536 1.43 61188 19878 2 1045.652622 523.8341 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.75 3706.5 - 665187 - - - -0.9047 - 1.306 0.324 - 108.1 1 2 0 -0.0009 9 0 0 0 6.62E+06 4.63E+06 - - - 2.2061 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19879.19879.2 0.397 16-Sep R.VLLPVLLNK.N sp|O00186|STXB3_HUMAN 1 1007.6743 1.87 61189 19879 2 1007.676492 504.8444 Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2 8.72 3706.6 - 657341 - - - 2.1723 - 1.902 0.263 - 258 1 2 0 0.0022 9 0 0 0 7.03E+06 3.75E+06 - - - 2.8428 1 230117_WJC_METTL3_WT_vs_EV_F07.19881.19881.2 0.00822 15/28 R.VMAGALEGDIFIGPK.A "sp|P61163|ACTZ_HUMAN,sp|P42025|ACTY_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 4 1516.796 1.56 61191 19881 2 1516.796348 759.4053 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4.37 3706.8 - 455339 - - - 0.2617 - 2.821 0.535 - 718.4 1 2 0 0.0004 15 0 0 0 1.50E+07 9.60E+06 - - - 5.5421 1 230117_WJC_METTL3_WT_vs_EV_F07.19882.19882.2 3.94E-07 26-Dec R.IMGIPEEEQMGLLR.V sp|P35579|MYH9_HUMAN 1 1614.8109 1.2 61192 19882 2 1614.810805 808.4128 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3706.8 - 442497 - - - -0.0892 - 2.315 0.65 - 335.6 1 2 0 -0.0001 14 0 0 0 6.09E+06 5.08E+06 - - - 5.9483 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19884.19884.2 0.000392 22-Oct K.YGLEGTVFFEEK.D "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1417.6765 4.8 61194 19884 2 1417.676877 709.8456 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.25 3707 - 282793 - - - 0.2321 - 2.038 0.49 - 231.2 1 2 0 0.0003 12 0 0 0 6.31E+06 1.32E+06 - - - 4.5333 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19888.19888.2 0.000298 18-Sep K.LLDEVFFSEK.L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1225.6231 1.61 61196 19888 2 1225.62396 613.8188 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3707.4 - 446032 - - - 0.7384 - 2.049 0.436 - 220.2 1 2 0 0.0009 10 0 0 0 2.89E+08 1.80E+08 - - - 4.2634 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19889.19889.2 0.0198 16-Aug K.VIPTLALLK.D sp|O14530|TXND9_HUMAN 1 966.6478 2.3 61197 19889 2 966.649164 484.3312 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 8.72 3707.5 - 102902 - - - 1.4586 - 1.43 0.347 - 161.4 1 2 0 0.0014 9 0 0 0 1.16E+07 5.03E+06 - - - 2.6383 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.19891.19891.2 0.395 14-Aug K.IPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1059.5502 1.22 61199 19891 2 1059.55142 530.7824 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3707.6 - 367984 - - - 1.1845 - 1.571 0.223 - 171.6 1 2 0 0.0013 8 0 0 0 4.51E+09 3.68E+09 - - - 2.05 0.9797 230117_WJC_METTL3_WT_vs_EV_F07.19892.19892.2 0.713 14-Jul R.SQFFITFR.S "sp|Q13356|PPIL2_HUMAN,tr|A0A7P0TA15|A0A7P0TA15_HUMAN,tr|A0A7P0TAH4|A0A7P0TAH4_HUMAN,tr|A0A7P0TB19|A0A7P0TB19_HUMAN,tr|A0A7P0Z4K4|A0A7P0Z4K4_HUMAN,tr|A0A7P0T8E8|A0A7P0T8E8_HUMAN,tr|A0A7P0T843|A0A7P0T843_HUMAN" 7 1044.5393 2.21 61200 19892 2 1044.538522 523.2769 RING-type E3 ubiquitin-protein ligase PPIL2 OS=Homo sapiens OX=9606 GN=PPIL2 PE=1 SV=1 9.47 3707.7 - 277431 - - - -0.7123 - 1.074 0.174 - 108.2 1 2 0 -0.0007 8 0 0 0 2.26E+06 1.02E+06 - - - 0.5412 1 230117_WJC_METTL3_WT_vs_EV_F07.19893.19893.2 0.000779 18-Nov K.LLDEVFFSEK[136.11].L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1233.6373 1.61 61201 19893 2 1233.637669 617.8259 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3707.8 - 245133 - - - 0.3356 - 2.221 0.464 - 286.7 1 2 0 0.0004 10 0 0 0 2.89E+08 1.80E+08 - - - 4.6953 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19895.19895.2 0.00238 16-Nov K.LFSNVLILK[136.11].S "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1053.6678 1.43 61203 19895 2 1053.670274 527.8412 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.75 3708 - 535484 - - - 2.3784 - 1.891 0.469 - 272.7 1 2 0 0.0025 9 0 0 0 6.62E+06 4.63E+06 - - - 4.3474 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.19896.19896.2 0.0387 16-Aug K.VIPTLALLK[136.11].D sp|O14530|TXND9_HUMAN 1 974.662 2.3 61204 19896 2 974.664089 488.3383 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 8.72 3708 - 305677 - - - 2.1905 - 1.084 0.438 - 113.2 1 2 0 0.0021 9 0 0 0 1.16E+07 5.03E+06 - - - 2.5087 0.9644 230117_WJC_METTL3_WT_vs_EV_F07.19897.19897.2 0.533 24-Jul K.TISGPLIPPASPR.L "sp|A6NGB9|WIPF3_HUMAN,tr|A0A0A0MSG0|A0A0A0MSG0_HUMAN" 2 1304.7452 16.26 61205 19897 2 1304.743432 653.3799 WAS\WASL-interacting protein family member 3 OS=Homo sapiens OX=9606 GN=WIPF3 PE=1 SV=4 9.41 3708.2 - 0 - - - -1.3826 - 1.409 0.112 - 53.4 5 2 0 -0.0018 13 0 0 0 2.94E+06 1.81E+05 - - - 0.4354 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.19899.19899.3 0.00163 15/76 R.LALVTGGEIASTFDHPELVK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2096.1154 -1 61207 19899 3 2096.118857 699.7124 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 3708.4 - 87139.9 - - - 1.6631 - 2.519 0.474 - 228.8 1 2 0 0.0035 20 0 0 0 0.00E+00 0.00E+00 - - - 6.065 1 230117_WJC_METTL3_WT_vs_EV_F07.19900.19900.2 0.000552 13/24 K.LLC[160.03]DSVVLQPYLR.E "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN,tr|H0YBB4|H0YBB4_HUMAN" 3 1574.8491 4.44 61208 19900 2 1574.851413 788.4318 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.83 3708.6 - 0 - - - 1.5005 - 2.5 0.53 - 616.8 1 2 0 0.0024 13 0 0 0 3.86E+06 8.69E+05 - - - 5.3065 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19901.19901.2 0.00287 22-Sep K.ALSTFFVENSLR[166.11].T sp|Q9Y2V7|COG6_HUMAN 1 1392.7277 2.39 61209 19901 2 1392.730609 697.3711 Conserved oligomeric Golgi complex subunit 6 OS=Homo sapiens OX=9606 GN=COG6 PE=1 SV=2 6.05 3708.6 - 354540 - - - 2.0995 - 1.618 0.334 - 259.7 1 2 0 0.0029 12 0 0 0 6.39E+06 2.68E+06 - - - 2.7731 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19903.19903.2 0.0527 20-Oct K.TAAFALPVLER.L "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 1186.671 1.13 61211 19903 2 1186.671529 594.3428 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.66 3708.9 - 0 - - - 0.4382 - 2.05 0.344 - 345.6 1 2 0 0.0005 11 0 0 0 1.12E+07 9.83E+06 - - - 3.5235 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.19907.19907.3 0.00179 Jul-36 K.LTLLTLHFPR.L "sp|Q92889|XPF_HUMAN,tr|A0A804HKF9|A0A804HKF9_HUMAN" 2 1209.7234 4.9 61215 19907 3 1209.724206 404.2484 DNA repair endonuclease XPF OS=Homo sapiens OX=9606 GN=ERCC4 PE=1 SV=3 9.76 3709.4 - 168211 - - - 0.6836 - 1.801 0.232 - 54.4 1 2 0 0.0008 10 0 0 0 1.41E+06 2.88E+05 - - - 2.8446 1 230117_WJC_METTL3_WT_vs_EV_F07.19912.19912.2 5.84E-07 15/22 R.IYGLGSLALYEK.A sp|P36542|ATPG_HUMAN 1 1325.7231 1.5 61218 19912 2 1325.724864 663.8688 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6 3709.9 - 9.95E+06 - - - 1.3276 - 2.86 0.494 - 686.1 1 2 0 0.0018 12 0 0 0 4.69E+08 3.12E+08 - - - 5.454 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19914.19914.2 0.0017 18-Sep K.SVLIGEFLEK.V "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1133.6332 0.9 61220 19914 2 1133.633846 567.8239 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 3710 - 1.61E+06 - - - 0.5469 - 1.749 0.419 - 253.8 1 2 0 0.0006 10 0 0 0 1.13E+08 1.26E+08 - - - 3.696 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.19915.19915.2 2.58E-05 16-Oct K.TMTLFSALR[166.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 1048.5615 0.98 61221 19915 2 1048.560827 525.288 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.41 3710.1 - 1.25E+06 - - - -0.6151 - 1.925 0.467 - 356.5 1 2 0 -0.0006 9 0 0 0 1.00E+07 1.02E+07 - - - 4.3848 1 230117_WJC_METTL3_WT_vs_EV_F07.19916.19916.2 2.19E-05 13/24 K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 0.21 61222 19916 2 1600.742603 801.3794 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3710.2 - 1.02E+06 - - - -1.0664 - 2.108 0.503 - 473.8 1 2 0 -0.0017 13 0 0 0 8.57E+06 4.10E+07 - - - 4.6696 1 230117_WJC_METTL3_WT_vs_EV_F07.19917.19917.3 7.08E-09 17/60 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 146.67 61223 19917 3 1787.005052 596.6753 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3710.4 - 1.01E+06 - - - 0.5719 - 3.534 0.524 - 498.1 1 2 0 0.001 16 0 0 0 3.49E+08 2.38E+06 - - - 7.621 1 230117_WJC_METTL3_WT_vs_EV_F07.19919.19919.2 2.36E-05 24-Dec A.TLSPTAVLILGPK.V "sp|Q8TDL5|BPIB1_HUMAN,tr|A2A2R0|A2A2R0_HUMAN" 2 1308.8017 999 61225 19919 2 1308.796776 655.4081 BPI fold-containing family B member 1 OS=Homo sapiens OX=9606 GN=BPIFB1 PE=1 SV=1 8.41 3710.6 - 746367 - - - -3.7531 - 2.421 0.574 - 402.4 1 1 0 -0.0049 13 0 0 0 4.39E+06 0.00E+00 - - - 5.5483 0.9798 230117_WJC_METTL3_WT_vs_EV_F07.19920.19920.2 0.715 14-Jun R.YILATLLK.E "sp|Q6PI48|SYDM_HUMAN,tr|A0A3B3IS01|A0A3B3IS01_HUMAN,tr|A0A3B3ISK7|A0A3B3ISK7_HUMAN,tr|A0A3B3IT01|A0A3B3IT01_HUMAN" 4 933.5899 0.93 61226 19920 2 933.589899 467.8022 "Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2 PE=1 SV=1" 8.59 3710.7 - 713047 - - - -0.0064 - 1.08 0.151 - 69.9 2 2 0 0 8 0 0 0 3.55E+06 3.82E+06 - - - 0.2539 1 230117_WJC_METTL3_WT_vs_EV_F07.19925.19925.2 1.62E-07 22-Dec K.ALEDAFLAIDAK.L sp|O15355|PPM1G_HUMAN 1 1275.6711 3.08 61229 19925 2 1275.671341 638.8428 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.03 3711.4 - 3.17E+06 - - - 0.214 - 2.327 0.526 - 437.8 1 2 0 0.0003 12 0 0 0 5.17E+07 1.68E+07 - - - 5.1482 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19927.19927.2 0.0078 18-Jun R.GPILLPYQFR.M "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1202.6812 1.48 61231 19927 2 1202.683133 602.3479 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 8.75 3711.5 - 1.01E+06 - - - 1.6247 - 1.513 0.426 - 160 1 2 0 0.002 10 0 0 0 2.08E+07 1.41E+07 - - - 3.3427 0.9932 230117_WJC_METTL3_WT_vs_EV_F07.19930.19930.2 0.62 18-May K.ELLGQGLLLR[166.11].S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1120.6844 0.86 61232 19930 2 1120.68675 561.3495 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3711.9 - 5.45E+06 - - - 2.1291 - 0.998 0.247 - 80.7 1 2 0 0.0024 10 0 0 0 1.57E+08 1.82E+08 - - - 0.859 1 230117_WJC_METTL3_WT_vs_EV_F07.19932.19932.2 3.05E-12 21/30 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 999 61234 19932 2 1787.004345 894.5093 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3712 - 4.49E+06 - - - 0.1763 - 3.862 0.531 - 1425 1 2 0 0.0003 16 0 0 0 1.07E+08 0.00E+00 - - - 6.2848 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19935.19935.2 0.000226 20-Sep R.EVWALVQAGIR.D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1240.6928 1.22 61237 19935 2 1240.693248 621.3537 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.1 3712.2 - 1.34E+06 - - - 0.3554 - 1.828 0.492 - 235.9 1 2 0 0.0004 11 0 0 0 7.60E+06 6.23E+06 - - - 4.3066 0.9832 230117_WJC_METTL3_WT_vs_EV_F07.19936.19936.2 4.02 18-Sep R.GPILLPYQFR[166.11].M "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1212.6894 1.48 61238 19936 2 1212.698538 607.352 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 8.75 3712.2 - 1.06E+06 - - - 7.4949 - 1.957 0.312 - 284.7 1 2 0 0.0091 10 0 0 0 2.08E+07 1.41E+07 - - - 3.2167 0.9552 230117_WJC_METTL3_WT_vs_EV_F07.19938.19938.2 0.0371 12-Aug L.PDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 956.4744 2.11 61240 19938 2 956.474166 479.2445 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 6.27 3712.4 - 795041 - - - -0.2143 - 1.821 0.384 - 272 1 1 0 -0.0002 7 0 0 0 5.67E+07 2.69E+07 - - - 3.7763 0.9352 230117_WJC_METTL3_WT_vs_EV_F07.19939.19939.2 0.32 20-Jun R.VLLQAFDVVER[166.11].S sp|Q15750|TAB1_HUMAN 1 1297.727 0.53 61241 19939 2 1297.721169 649.8708 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 OS=Homo sapiens OX=9606 GN=TAB1 PE=1 SV=1 4.37 3712.5 - 699158 - - - -4.4601 - 1.35 0.24 - 92.7 3 2 0 -0.0058 11 0 0 0 1.53E+07 2.88E+07 - - - 1.4105 0.9728 230117_WJC_METTL3_WT_vs_EV_F07.19947.19947.2 0.0235 12-Aug L.PDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 946.4661 1.27 61247 19947 2 946.466711 474.2403 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 6.27 3713.4 - 3.35E+06 - - - 0.6445 - 1.778 0.426 - 279.5 1 1 0 0.0006 7 0 0 0 3.30E+07 2.59E+07 - - - 4.0107 0.999 230117_WJC_METTL3_WT_vs_EV_F07.19948.19948.2 0.885 14-Sep R.LSLELFGR.V "sp|O95071|UBR5_HUMAN,tr|E5RFK7|E5RFK7_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 933.5284 1.92 61248 19948 2 933.530095 467.7715 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 6 3713.5 - 1.34E+06 - - - 1.851 - 1.778 0.229 - 242.2 1 2 0 0.0017 8 0 0 0 2.28E+07 1.19E+07 - - - 2.4675 1 230117_WJC_METTL3_WT_vs_EV_F07.19949.19949.2 2.78E-07 20-Nov R.WGAFAQSILER[166.11].G sp|Q13472|TOP3A_HUMAN 1 1286.6647 0.22 61249 19949 2 1286.662864 644.3396 DNA topoisomerase 3-alpha OS=Homo sapiens OX=9606 GN=TOP3A PE=1 SV=1 6 3713.6 - 1.37E+06 - - - -1.42 - 2.442 0.529 - 506.8 1 2 0 -0.0018 11 0 0 0 2.43E+06 1.09E+07 - - - 5.3629 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.19950.19950.2 0.121 14-Jul R.MGLLAVLR.S "sp|O95394|AGM1_HUMAN,tr|D6RF77|D6RF77_HUMAN,tr|D6RC77|D6RC77_HUMAN,tr|D6RCQ8|D6RCQ8_HUMAN,tr|A0A494C099|A0A494C099_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C163|A0A494C163_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|D6RCD1|D6RCD1_HUMAN" 9 871.5313 1.78 61250 19950 2 871.533695 436.7729 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 9.5 3713.7 - 696561 - - - 2.6976 - 1.59 0.355 - 196 1 2 0 0.0024 8 0 0 0 5.17E+06 2.90E+06 - - - 3.0609 0.998 230117_WJC_METTL3_WT_vs_EV_F07.19951.19951.2 0.0518 12-Jun K.DAFLVFR.S "sp|Q9Y6D6|BIG1_HUMAN,sp|Q9Y6D5|BIG2_HUMAN,tr|A0A7P0T7Z2|A0A7P0T7Z2_HUMAN,tr|A0A7P0T9L9|A0A7P0T9L9_HUMAN,tr|A0A7P0TA34|A0A7P0TA34_HUMAN,tr|A0A7P0T9L6|A0A7P0T9L6_HUMAN" 6 866.465 1.88 61251 19951 2 866.465843 434.2398 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens OX=9606 GN=ARFGEF1 PE=1 SV=2 5.84 3713.8 - 689302 - - - 0.9291 - 1.245 0.271 - 111.7 1 2 0 0.0008 7 0 0 0 4.31E+06 2.30E+06 - - - 1.7367 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.19952.19952.2 0.00601 15/22 K.LANILFTQELAR[166.11].R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1397.7906 1.27 61252 19952 2 1397.78815 699.9026 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3714 - 608314 - - - -1.7671 - 2.711 0.287 - 1024.7 1 2 0 -0.0025 12 0 0 0 2.40E+07 1.89E+07 - - - 3.7841 0.9939 230117_WJC_METTL3_WT_vs_EV_F07.19957.19957.2 3.62E-09 17/24 R.GAAGALLVYDITR.R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1318.7245 0.74 61255 19957 2 1318.719717 660.3695 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3714.6 - 637064 - - - -3.6277 - 3.308 0.182 - 1454.7 1 2 0 -0.0048 13 0 0 0 5.43E+07 7.31E+07 - - - 3.4542 1 230117_WJC_METTL3_WT_vs_EV_F07.19962.19962.2 2.46E-06 20-Dec K.SFYGSTLFLC[160.03]R.R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1349.6438 1.39 61260 19962 2 1349.642651 675.8292 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 7.94 3715.3 - 325583 - - - -0.8573 - 2.246 0.568 - 478.9 1 2 0 -0.0012 11 0 0 0 5.63E+06 4.05E+06 - - - 5.4248 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.19965.19965.2 0.00815 14/22 K.LANILFTQELAR.R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1387.7823 1.27 61261 19965 2 1387.780195 694.8985 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3715.7 - 1.64E+06 - - - -1.5528 - 2.921 0.26 - 858.8 1 2 0 -0.0022 12 0 0 0 2.41E+07 1.89E+07 - - - 3.7811 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.19966.19966.2 0.12 18-Nov R.VDLPLAVLSK.M "sp|Q9H773|DCTP1_HUMAN,tr|H3BSA6|H3BSA6_HUMAN" 2 1053.6434 15.24 61262 19966 2 1053.646072 527.829 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 5.81 3715.8 - 1.11E+06 - - - 2.5388 - 2.265 0.382 - 276.6 1 2 0 0.0027 10 0 0 0 3.45E+07 2.26E+06 - - - 4.1437 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.19967.19967.2 0.00226 18-Sep K.ELLGQGLLLR.S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1110.6761 0.86 61263 19967 2 1110.675727 556.3453 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3715.8 - 1.16E+07 - - - -0.3304 - 1.949 0.326 - 317.1 1 2 0 -0.0004 10 0 0 0 1.57E+08 1.82E+08 - - - 3.3114 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.19968.19968.2 0.000393 20-Oct K.ALLLSSVLSEK.G "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1158.686 2.96 61264 19968 2 1158.683345 580.3503 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 6.05 3716 - 1.40E+06 - - - -2.2828 - 2.243 0.36 - 304.3 1 2 0 -0.0026 11 0 0 0 1.52E+07 5.14E+06 - - - 3.8845 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.19969.19969.2 3.64E-05 13/20 R.VLLQAFDVVER.S sp|Q15750|TAB1_HUMAN 1 1287.7187 0.53 61265 19969 2 1287.717523 644.8666 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 OS=Homo sapiens OX=9606 GN=TAB1 PE=1 SV=1 4.37 3716.1 - 1.12E+06 - - - -0.9039 - 2.558 0.256 - 670.4 1 2 0 -0.0012 11 0 0 0 1.53E+07 2.87E+07 - - - 3.4723 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.19974.19974.2 0.00922 20-Nov K.SFYGSTLFLC[160.03]R[166.11].R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1359.6521 1.39 61270 19974 2 1359.654754 680.8333 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 7.94 3716.7 - 428407 - - - 1.9682 - 1.89 0.374 - 373.6 1 2 0 0.0027 11 0 0 0 5.63E+06 4.05E+06 - - - 3.5246 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.19975.19975.2 0.000595 18-Oct K.QLEDILVLAK[136.11].Q "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A0A6YYJ5|A0A0A6YYJ5_HUMAN" 8 1148.6896 5.09 61271 19975 2 1148.686942 575.3521 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.37 3716.9 - 350030 - - - -2.3357 - 1.88 0.426 - 237.8 1 2 0 -0.0027 10 0 0 0 2.66E+07 5.23E+06 - - - 3.9487 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.19976.19976.2 0.0114 12-Jun K.ELFEMWK.L sp|Q9H9J2|RM44_HUMAN 1 981.463 0.64 61272 19976 2 981.464972 491.7388 "39S ribosomal protein L44, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL44 PE=1 SV=1" 4.53 3717 - 233835 - - - 2.0194 - 1.227 0.371 - 114.5 1 2 0 0.002 7 0 0 0 1.21E+06 1.88E+06 - - - 2.4288 0.999 230117_WJC_METTL3_WT_vs_EV_F07.19977.19977.2 0.000251 22-Nov R.LFSNFSGADLLK.L "sp|Q9NZI7|UBIP1_HUMAN,tr|F8WEP8|F8WEP8_HUMAN" 2 1310.6871 2.07 61273 19977 2 1310.687633 656.3508 Upstream-binding protein 1 OS=Homo sapiens OX=9606 GN=UBP1 PE=1 SV=1 5.84 3717.1 - 212260 - - - 0.4425 - 2.169 0.208 - 227.2 1 2 0 0.0006 12 0 0 0 5.13E+06 2.48E+06 - - - 2.6143 1 230117_WJC_METTL3_WT_vs_EV_F07.19984.19984.2 0.00444 16-Nov R.ILDTLGLLR.Q "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN,tr|A0A087WWF4|A0A087WWF4_HUMAN" 3 1012.6281 1.21 61278 19984 2 1012.628868 507.3213 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 5.84 3717.9 - 5.67E+06 - - - 0.7772 - 2.449 0.46 - 305 1 2 0 0.0008 9 0 0 0 1.57E+07 1.30E+07 - - - 5.0296 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19985.19985.2 0.000533 16-Nov R.ILDTLGLLR[166.11].Q "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN,tr|A0A087WWF4|A0A087WWF4_HUMAN" 3 1022.6364 1.21 61279 19985 2 1022.637117 512.3255 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 5.84 3718.1 - 5.20E+06 - - - 0.749 - 2.166 0.421 - 279.8 1 2 0 0.0008 9 0 0 0 1.57E+07 1.30E+07 - - - 4.3863 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.19986.19986.2 0.000126 22-Oct K.IDVLQAEVAALK[136.11].T "sp|Q96QF0|RAB3I_HUMAN,tr|H0YI02|H0YI02_HUMAN,tr|J3KPG1|J3KPG1_HUMAN" 3 1276.7482 1.04 61280 19986 2 1276.749521 639.3814 Rab-3A-interacting protein OS=Homo sapiens OX=9606 GN=RAB3IP PE=1 SV=1 4.37 3718.1 - 2.27E+06 - - - 1.0323 - 2.086 0.429 - 315.1 1 2 0 0.0013 12 0 0 0 9.00E+06 8.64E+06 - - - 4.1437 0.998 230117_WJC_METTL3_WT_vs_EV_F07.19987.19987.2 0.105 14-Jul R.LSLELFGR[166.11].V "sp|O95071|UBR5_HUMAN,tr|E5RFK7|E5RFK7_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 943.5366 1.92 61281 19987 2 943.536847 472.7756 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 6 3718.3 - 1.98E+06 - - - 0.2226 - 1.593 0.206 - 124.5 1 2 0 0.0002 8 0 0 0 2.28E+07 1.19E+07 - - - 1.9667 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.19989.19989.2 0.0203 18-Aug R.DALVMAQILK.D sp|Q9HBM6|TAF9B_HUMAN 1 1100.6264 0.81 61283 19989 2 1100.626314 551.3205 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 5.84 3718.5 - 1.85E+06 - - - -0.0482 - 1.593 0.321 - 140.8 1 2 0 -0.0001 10 0 0 0 2.13E+07 2.63E+07 - - - 2.7116 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.19991.19991.2 0.000415 20-Oct K.IESLPPLLIGK.F "sp|Q8N9N7|LRC57_HUMAN,tr|A0A3B3ISV5|A0A3B3ISV5_HUMAN,tr|H3BSW0|H3BSW0_HUMAN" 3 1178.7275 2.99 61285 19991 2 1178.72676 590.371 Leucine-rich repeat-containing protein 57 OS=Homo sapiens OX=9606 GN=LRRC57 PE=1 SV=1 6 3718.7 - 1.38E+06 - - - -0.5947 - 1.921 0.434 - 187 1 2 0 -0.0007 11 0 0 0 8.49E+06 2.84E+06 - - - 4.0124 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.19993.19993.2 0.000857 24-Nov R.LVDIIAAVPPQYR[166.11].K "sp|Q9H9T3|ELP3_HUMAN,tr|E5RIZ7|E5RIZ7_HUMAN,tr|E5RIC0|E5RIC0_HUMAN,tr|E5RHY2|E5RHY2_HUMAN,tr|E5RHR2|E5RHR2_HUMAN" 5 1463.8376 1.71 61287 19993 2 1463.834558 732.9261 Elongator complex protein 3 OS=Homo sapiens OX=9606 GN=ELP3 PE=1 SV=2 5.84 3719 - 1.00E+06 - - - -2.0576 - 2.379 0.4 - 378.2 1 2 0 -0.003 13 0 0 0 5.03E+06 2.94E+06 - - - 4.2188 0.9303 230117_WJC_METTL3_WT_vs_EV_F07.19996.19996.3 0.00039 Oct-48 R.GAAGALLVYDITR.R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1318.7245 2.02 61290 19996 3 1318.722876 440.5821 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3719.4 - 693167 - - - -1.2323 - 1.887 0.059 - 161.2 1 2 0 -0.0016 13 0 0 0 4.53E+06 2.24E+06 - - - 0.919 0.9388 230117_WJC_METTL3_WT_vs_EV_F07.19998.19998.3 0.000113 Nov-48 R.GAAGALLVYDITR[166.11].R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1328.7328 1.95 61292 19998 3 1328.734246 443.9182 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3719.6 - 517670 - - - 1.1101 - 1.73 0.03 - 98.1 1 2 0 0.0015 13 0 0 0 4.12E+06 2.11E+06 - - - 0.3602 1 230117_WJC_METTL3_WT_vs_EV_F07.20005.20005.2 1.42E-05 14/22 K.PYRPWGTEIGAF.- "sp|Q9Y5J3|HEY1_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 4 1392.6826 1.69 61297 20005 2 1392.681637 697.3486 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 6.43 3720.4 - 892620 - - - -0.7173 - 2.209 0.493 - 571.4 1 1 0 -0.001 12 0 0 0 7.75E+06 4.60E+06 - - - 4.7673 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.20007.20007.2 6.43E-08 15/24 R.GAAGALLVYDITR[166.11].R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1328.7328 1.3 61299 20007 2 1328.736247 665.3737 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3720.5 - 699992 - - - 2.616 - 3.394 0.161 - 1102.8 1 2 0 0.0035 13 0 0 0 9.73E+07 7.47E+07 - - - 3.3654 0.8721 230117_WJC_METTL3_WT_vs_EV_F07.20008.20008.2 0.00111 22-Oct K.PYR[166.11]PWGTEIGAF.- "sp|Q9Y5J3|HEY1_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 4 1402.6909 1.69 61300 20008 2 1402.697251 702.3527 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 6.43 3720.6 - 364400 - - - 4.5234 - 1.892 0.407 - 330 1 1 0 0.0063 12 0 0 0 7.75E+06 4.60E+06 - - - 3.7228 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.20012.20012.2 0.00121 14/20 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 15.49 61302 20012 2 1276.700548 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3721.1 - 1.89E+06 - - - -1.6879 - 2.696 0.36 - 946.2 1 2 0 -0.0022 11 0 0 0 7.90E+07 5.10E+06 - - - 4.3823 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20013.20013.2 0.0628 18-Dec K.IINFAPSLLR[166.11].L "sp|O15397|IPO8_HUMAN,tr|F5H2I3|F5H2I3_HUMAN" 2 1152.6894 1.19 61303 20013 2 1152.690983 577.352 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 9.75 3721.3 - 1.05E+06 - - - 1.3308 - 2.251 0.371 - 390 1 2 0 0.0015 10 0 0 0 2.36E+07 1.99E+07 - - - 4.0455 0.997 230117_WJC_METTL3_WT_vs_EV_F07.20017.20017.2 0.198 14-Jul R.SLPVFPFR.E "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 961.5385 1.66 61307 20017 2 961.539602 481.7765 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 9.47 3721.8 - 891592 - - - 1.1066 - 1.254 0.224 - 222.7 1 2 0 0.0011 8 0 0 0 6.73E+06 4.06E+06 - - - 1.3778 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20018.20018.2 0.000573 22-Dec K.YLGPAVLMQAYR.W sp|P21912|SDHB_HUMAN 1 1380.7224 2.4 61308 20018 2 1380.723929 691.3685 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 8.59 3721.9 - 739591 - - - 1.1132 - 1.87 0.418 - 357.3 1 2 0 0.0015 12 0 0 0 1.29E+07 5.36E+06 - - - 3.7748 1 230117_WJC_METTL3_WT_vs_EV_F07.20019.20019.2 0.000216 22-Nov K.IYDALDVSLIER[166.11].G sp|P54136|SYRC_HUMAN 1 1415.7536 1.4 61309 20019 2 1415.753485 708.8841 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.03 3722 - 666239 - - - -0.0572 - 2.488 0.547 - 454.7 1 2 0 -0.0001 12 0 0 0 9.62E+06 6.88E+06 - - - 5.4794 1 230117_WJC_METTL3_WT_vs_EV_F07.20022.20022.2 3.21E-08 26-Dec K.FYGPAGPYGIFAGR[166.11].D sp|O15173|PGRC2_HUMAN 1 1481.7331 1.45 61312 20022 2 1481.733199 741.8738 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3722.4 - 475309 - - - 0.0634 - 2.242 0.607 - 425.8 1 2 0 0.0001 14 0 0 0 2.30E+07 1.59E+07 - - - 5.5503 1 230117_WJC_METTL3_WT_vs_EV_F07.20024.20024.2 1.29E-05 18-Nov R.LNDYIFSFDK.M sp|P54136|SYRC_HUMAN 1 1260.6027 1.55 61314 20024 2 1260.597404 631.3086 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.21 3722.7 - 387671 - - - -4.1647 - 2.47 0.506 - 722.1 1 2 0 -0.0053 10 0 0 0 3.79E+06 2.45E+06 - - - 5.3006 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.20025.20025.2 0.0188 18-Jul R.NVEELVIVLK[136.11].K "sp|P53618|COPB_HUMAN,tr|E9PP73|E9PP73_HUMAN" 2 1162.7053 3.54 61315 20025 2 1162.709061 582.3599 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 4.53 3722.8 - 355618 - - - 3.2562 - 1.568 0.388 - 93.6 1 2 0 0.0038 10 0 0 0 6.46E+06 1.82E+06 - - - 3.1611 0.9367 230117_WJC_METTL3_WT_vs_EV_F07.20027.20027.3 0.331 Jul-32 K.EFIHILYFR.H "sp|Q9NZ32|ARP10_HUMAN,tr|G3V2Q5|G3V2Q5_HUMAN,tr|G3V5Y4|G3V5Y4_HUMAN,tr|F6S9Y6|F6S9Y6_HUMAN,tr|V9GYX7|V9GYX7_HUMAN" 5 1236.6655 1.28 61317 20027 3 1236.663753 413.2291 Actin-related protein 10 OS=Homo sapiens OX=9606 GN=ACTR10 PE=1 SV=1 6.85 3723.1 - 263140 - - - -1.4361 - 1.293 0.157 - 60.3 1 2 0 -0.0018 9 0 0 0 1.53E+06 1.19E+06 - - - 1.0643 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.20028.20028.2 0.038 12-Jul R.WLSQYID.- "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 923.4389 - 61318 20028 2 923.439332 462.7267 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.3 3723.2 - 185210 - - - 0.4862 - 1.28 0.259 - 107 1 2 0 0.0004 7 0 0 0 - - - - - 1.736 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.20035.20035.2 0.0621 18-Aug R.AAFVLPEFAR.K "sp|P19623|SPEE_HUMAN,tr|K7EL89|K7EL89_HUMAN" 2 1119.6077 5.84 61323 20035 2 1119.607489 560.8111 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 6.05 3723.9 - 2.47E+06 - - - -0.1706 - 1.685 0.306 - 161.3 1 2 0 -0.0002 10 0 0 0 4.71E+07 8.06E+06 - - - 2.7575 0.9701 230117_WJC_METTL3_WT_vs_EV_F07.20036.20036.2 3.55 12-May K.LLDDLFR[166.11].K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 900.4944 0.99 61324 20036 2 900.493633 451.2545 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3723.9 - 2.08E+06 - - - -0.894 - 1.19 0.102 - 71.1 1 2 0 -0.0008 7 0 0 0 8.29E+07 8.37E+07 - - - 0.3453 0.9916 230117_WJC_METTL3_WT_vs_EV_F07.20037.20037.2 0.446 12-Jun K.LLDDLFR.K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 890.4862 0.98 61325 20037 2 890.486269 446.2504 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3724 - 2.07E+06 - - - 0.1134 - 1.261 0.143 - 111.3 1 2 0 0.0001 7 0 0 0 8.29E+07 8.48E+07 - - - 0.832 0.9962 230117_WJC_METTL3_WT_vs_EV_F07.20040.20040.2 3.21E-05 24-Sep R.AGLNGLQLAVLAR.L sp|Q96S55|WRIP1_HUMAN 1 1294.7721 7.95 61328 20040 2 1294.770524 648.3933 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 9.79 3724.1 - 813908 - - - -1.2326 - 2.053 0.176 - 321.5 1 2 0 -0.0016 13 0 0 0 6.80E+06 8.56E+05 - - - 2.1865 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20041.20041.2 0.23 20-Nov -.MLLFVEQVASK.G "sp|Q71RC2|LARP4_HUMAN,tr|F8W1Z5|F8W1Z5_HUMAN" 2 1263.6897 0.33 61329 20041 2 1263.689613 632.8521 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 5.75 3724.2 - 732120 - - - -0.0649 - 2.097 0.368 - 345.7 1 2 0 -0.0001 11 0 0 0 9.02E+06 2.75E+07 - - - 3.7623 1 230117_WJC_METTL3_WT_vs_EV_F07.20046.20046.2 9.29E-08 16/20 K.TAVETAVLLLR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1194.7211 9.3 61332 20046 2 1194.721471 598.3678 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3724.8 - 6.08E+06 - - - 0.2745 - 2.927 0.581 - 1065.8 1 2 0 0.0003 11 0 0 0 1.10E+09 1.19E+08 - - - 6.2375 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20050.20050.2 0.011 16-Oct K.YLGLLENLR[166.11].V "sp|O00159|MYO1C_HUMAN,tr|F5H6E2|F5H6E2_HUMAN" 2 1099.6265 1.8 61336 20050 2 1099.627777 550.8205 Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4 6 3725.3 - 1.24E+06 - - - 1.1477 - 1.652 0.367 - 330.5 1 2 0 0.0013 9 0 0 0 4.49E+06 2.50E+06 - - - 3.2035 1 230117_WJC_METTL3_WT_vs_EV_F07.20051.20051.2 2.82E-05 16-Oct K.YDWDLLAAR[166.11].S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1131.5588 1.68 61337 20051 2 1131.560884 566.7867 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3725.4 - 1.21E+06 - - - 1.8161 - 2.037 0.49 - 392.5 1 2 0 0.0021 9 0 0 0 5.20E+07 3.10E+07 - - - 4.7178 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20053.20053.2 0.0401 16-Sep K.YLGLLENLR.V "sp|O00159|MYO1C_HUMAN,tr|F5H6E2|F5H6E2_HUMAN" 2 1089.6182 0.18 61339 20053 2 1089.619501 545.8164 Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4 6 3725.7 - 1.08E+06 - - - 1.1527 - 1.896 0.366 - 254.8 1 2 0 0.0013 9 0 0 0 2.39E+06 1.29E+07 - - - 3.5947 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.20055.20055.2 0.0258 14-Jul R.DWVLNEFK.H "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1049.5182 1.43 61341 20055 2 1049.518324 525.7664 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3725.9 - 874033 - - - 0.122 - 1.365 0.254 - 208.4 1 2 0 0.0001 8 0 0 0 6.68E+07 4.68E+07 - - - 1.8554 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.20056.20056.2 0.0578 14-Sep R.LIFLDSIK.S "sp|Q99996|AKAP9_HUMAN,tr|A0A0A0MRF6|A0A0A0MRF6_HUMAN,tr|A0A7P0TBH8|A0A7P0TBH8_HUMAN,tr|A0A7P0TAX3|A0A7P0TAX3_HUMAN,tr|A0A7P0T9A9|A0A7P0T9A9_HUMAN,tr|A0A7P0T8N5|A0A7P0T8N5_HUMAN,tr|A0A7P0TBI4|A0A7P0TBI4_HUMAN,tr|A0A7P0Z4Q5|A0A7P0Z4Q5_HUMAN,tr|A0A7P0Z4N5|A0A7P0Z4N5_HUMAN,tr|A0A7P0TAD6|A0A7P0TAD6_HUMAN,tr|A0A7P0T939|A0A7P0T939_HUMAN,tr|A0A7P0T928|A0A7P0T928_HUMAN,tr|A0A7P0TAA2|A0A7P0TAA2_HUMAN" 13 947.5692 1.61 61342 20056 2 947.569622 474.7919 A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4 5.84 3726 - 792853 - - - 0.4781 - 1.433 0.291 - 171.5 1 2 0 0.0005 8 0 0 0 2.98E+06 1.86E+06 - - - 2.2752 0.9486 230117_WJC_METTL3_WT_vs_EV_F07.20057.20057.2 0.000962 22-Oct K.LLQVASPFLEPH.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1349.7343 - 61343 20057 2 1349.735751 675.8744 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 5.24 3726.1 - 776058 - - - 1.0476 - 1.654 0.335 - 138.7 1 1 0 0.0014 12 0 0 0 - - - - - 2.8389 0.9951 230117_WJC_METTL3_WT_vs_EV_F07.20058.20058.2 0.0722 14-Jul R.LIFLDSIK[136.11].S "sp|Q99996|AKAP9_HUMAN,tr|A0A0A0MRF6|A0A0A0MRF6_HUMAN,tr|A0A7P0TBH8|A0A7P0TBH8_HUMAN,tr|A0A7P0TAX3|A0A7P0TAX3_HUMAN,tr|A0A7P0T9A9|A0A7P0T9A9_HUMAN,tr|A0A7P0T8N5|A0A7P0T8N5_HUMAN,tr|A0A7P0TBI4|A0A7P0TBI4_HUMAN,tr|A0A7P0Z4Q5|A0A7P0Z4Q5_HUMAN,tr|A0A7P0Z4N5|A0A7P0Z4N5_HUMAN,tr|A0A7P0TAD6|A0A7P0TAD6_HUMAN,tr|A0A7P0T939|A0A7P0T939_HUMAN,tr|A0A7P0T928|A0A7P0T928_HUMAN,tr|A0A7P0TAA2|A0A7P0TAA2_HUMAN" 13 955.5834 1.72 61344 20058 2 955.584173 478.799 A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4 5.84 3726.3 - 710524 - - - 0.8414 - 1.366 0.143 - 114.3 1 2 0 0.0008 8 0 0 0 3.20E+06 1.86E+06 - - - 1.0376 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.20059.20059.3 0.00025 15/40 K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 7.31 61345 20059 3 1184.713791 395.9116 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3726.4 - 573248 - - - 0.7749 - 2.862 0.377 - 308.2 1 2 0 0.0009 11 0 0 0 2.71E+07 3.70E+06 - - - 5.7301 0.9835 230117_WJC_METTL3_WT_vs_EV_F07.20060.20060.2 0.475 14-Aug K.GIILFISR.N "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 917.5698 0.17 61346 20060 2 917.569435 459.7922 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3726.5 - 945514 - - - -0.4392 - 1.255 0.114 - 159.4 1 2 0 -0.0004 8 0 0 0 1.70E+06 9.98E+06 - - - 0.5679 1 230117_WJC_METTL3_WT_vs_EV_F07.20062.20062.2 4.53E-07 28-Nov R.LYGPSSVSFADDFVR.S "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 1658.794 999 61348 20062 2 1658.796833 830.4043 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.21 3726.8 - 414584 - - - 1.6856 - 2.244 0.551 - 272.7 1 2 0 0.0028 15 0 0 0 2.23E+06 0.00E+00 - - - 5.097 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20067.20067.2 0.00737 14-Sep K.IPDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1069.5584 1.22 61352 20067 2 1069.559418 535.7865 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3727.4 - 8.70E+06 - - - 0.9191 - 1.866 0.457 - 474.4 1 2 0 0.001 8 0 0 0 4.51E+09 3.68E+09 - - - 4.2974 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.20068.20068.2 0.00454 16-Aug K.FFPLIEVNK.V "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1105.6172 0.84 61353 20068 2 1105.617 553.8159 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6 3727.5 - 3.36E+06 - - - -0.1646 - 1.438 0.401 - 179.6 1 2 0 -0.0002 9 0 0 0 1.96E+08 2.32E+08 - - - 3.0536 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20069.20069.2 0.0164 18-Oct R.LLVVYPWTQR.F "sp|P69892|HBG2_HUMAN,sp|P69891|HBG1_HUMAN,sp|P02042|HBD_HUMAN,sp|P02100|HBE_HUMAN,sp|P68871|HBB_HUMAN,tr|A0A2R8Y7R2|A0A2R8Y7R2_HUMAN,tr|E9PEW8|E9PEW8_HUMAN,tr|E9PFT6|E9PFT6_HUMAN,tr|F8W6P5|F8W6P5_HUMAN,tr|A0A2R8Y7X9|A0A2R8Y7X9_HUMAN" 10 1273.7183 55.83 61354 20069 2 1273.71957 637.8664 Hemoglobin subunit gamma-2 OS=Homo sapiens OX=9606 GN=HBG2 PE=1 SV=2 8.75 3727.5 - 1.54E+06 - - - 1.0026 - 1.936 0.343 - 424.5 1 2 0 0.0013 10 0 0 0 3.23E+07 5.79E+05 - - - 3.418 1 230117_WJC_METTL3_WT_vs_EV_F07.20070.20070.2 1.36E-10 14/26 K.FYGPAGPYGIFAGR.D sp|O15173|PGRC2_HUMAN 1 1471.7248 1.45 61355 20070 2 1471.726836 736.8697 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3727.6 - 1.19E+06 - - - 1.3596 - 2.608 0.55 - 663.1 1 2 0 0.002 14 0 0 0 2.30E+07 1.59E+07 - - - 5.5082 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20072.20072.2 0.00302 12-Aug K.NMFAIWR.V "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 936.464 0.96 61357 20072 2 936.465439 469.2393 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3727.8 - 632877 - - - 1.5441 - 1.502 0.397 - 351.4 1 2 0 0.0014 7 0 0 0 4.30E+07 4.46E+07 - - - 3.2617 1 230117_WJC_METTL3_WT_vs_EV_F07.20075.20075.2 5.73E-05 13/18 R.QEVVDLLLAR[166.11].G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1164.6742 1.34 61360 20075 2 1164.676612 583.3444 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3728.1 - 222475 - - - 2.077 - 2.576 0.568 - 1013.2 1 2 0 0.0024 10 0 0 0 3.69E+07 2.74E+07 - - - 5.8767 1 230117_WJC_METTL3_WT_vs_EV_F07.20076.20076.2 4.37E-05 20-Dec K.FDGILGMAYPR.L "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1238.6118 8.25 61361 20076 2 1238.606048 620.3132 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.84 3728.2 - 221923 - - - -4.627 - 2.348 0.456 - 662.8 1 2 0 -0.0057 11 0 0 0 1.15E+07 1.40E+06 - - - 4.7163 1 230117_WJC_METTL3_WT_vs_EV_F07.20077.20077.2 7.10E-05 18-Dec R.QEVVDLLLAR.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1154.6659 1.34 61362 20077 2 1154.666932 578.3402 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3728.3 - 214911 - - - 0.8738 - 2.525 0.539 - 851.7 1 2 0 0.001 10 0 0 0 3.69E+07 2.74E+07 - - - 5.6072 1 230117_WJC_METTL3_WT_vs_EV_F07.20085.20085.2 5.45E-06 16-Sep K.YDWDLLAAR.S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1121.5506 1.64 61368 20085 2 1121.550613 561.7826 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3729.3 - 7.75E+06 - - - 0.0481 - 1.931 0.556 - 374.1 1 2 0 0.0001 9 0 0 0 5.22E+07 3.19E+07 - - - 5.0513 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.20086.20086.2 0.0114 16-Jul R.LVLDPYLLK.Y "sp|Q9Y2R5|RT17_HUMAN,tr|I3L0E3|I3L0E3_HUMAN,tr|E9PE17|E9PE17_HUMAN" 3 1072.6532 0.89 61369 20086 2 1072.655409 537.3339 "28S ribosomal protein S17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS17 PE=1 SV=1" 5.83 3729.4 - 3.25E+06 - - - 2.0286 - 1.169 0.433 - 131.7 1 2 0 0.0022 9 0 0 0 1.66E+07 1.88E+07 - - - 2.6902 1 230117_WJC_METTL3_WT_vs_EV_F07.20090.20090.2 2.83E-06 13/24 R.VETPVLPPVLVPR.H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1414.8548 2.01 61373 20090 2 1414.853495 708.4347 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3729.9 - 769067 - - - -0.9132 - 2.421 0.583 - 415.5 1 2 0 -0.0013 13 0 0 0 1.11E+07 5.50E+06 - - - 5.6159 0.9861 230117_WJC_METTL3_WT_vs_EV_F07.20091.20091.2 1.53 12-Jul K.DIILPFR.V "sp|Q96CW1|AP2M1_HUMAN,tr|A0A087WY71|A0A087WY71_HUMAN,tr|C9JJ47|C9JJ47_HUMAN,tr|E9PFW3|E9PFW3_HUMAN" 4 872.512 1.73 61374 20091 2 872.512676 437.2633 AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2 5.84 3730 - 751174 - - - 0.7874 - 1.485 0 - 224.3 1 2 0 0.0007 7 0 0 0 1.58E+07 9.14E+06 - - - 0.2937 0.9132 230117_WJC_METTL3_WT_vs_EV_F07.20092.20092.2 2.58 12-Jul K.DIILPFR[166.11].V "sp|Q96CW1|AP2M1_HUMAN,tr|A0A087WY71|A0A087WY71_HUMAN,tr|C9JJ47|C9JJ47_HUMAN,tr|E9PFW3|E9PFW3_HUMAN" 4 882.5203 1.74 61375 20092 2 882.519031 442.2674 AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2 5.84 3730.1 - 683027 - - - -1.3915 - 1.277 0 - 233.7 1 2 0 -0.0012 7 0 0 0 1.58E+07 9.07E+06 - - - -0.1846 0.9965 230117_WJC_METTL3_WT_vs_EV_F07.20093.20093.2 0.0211 20-Sep R.IAIQGIITAIK.Y sp|Q6NSI4|RADX_HUMAN 1 1139.7278 2.53 61376 20093 2 1139.725133 570.8712 RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2 8.75 3730.2 - 676879 - - - -2.3356 - 1.623 0.37 - 150.3 1 2 0 -0.0027 11 0 0 0 3.08E+06 1.22E+06 - - - 3.0831 0.975 230117_WJC_METTL3_WT_vs_EV_F07.20094.20094.2 0.216 16-Jun K.SLTYLSILR[166.11].N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 3 1074.6313 1.29 61377 20094 2 1074.628254 538.3229 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 8.46 3730.2 - 3.25E+06 - - - -2.8028 - 1.203 0.244 - 75.2 1 2 0 -0.003 9 0 0 0 1.33E+07 1.03E+07 - - - 1.3769 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.20097.20097.2 0.000184 16-Aug R.GFFGFPGPR.S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 980.4868 2.11 61380 20097 2 980.486256 491.2507 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3730.6 - 439544 - - - -0.5926 - 1.647 0.455 - 182.9 1 2 0 -0.0006 9 0 0 0 4.80E+07 2.28E+07 - - - 3.845 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.20102.20102.2 0.0203 14-Jul R.DWVLNEFK[136.11].H "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1057.5324 1.43 61383 20102 2 1057.533646 529.7735 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3731.3 - 3.52E+06 - - - 1.182 - 1.502 0.328 - 203.3 1 2 0 0.0013 8 0 0 0 6.68E+07 4.68E+07 - - - 2.6901 0.9943 230117_WJC_METTL3_WT_vs_EV_F07.20104.20104.2 0.00544 18-Sep K.GIGFLTSGWR.F sp|Q8IXM3|RM41_HUMAN 1 1092.5716 1.06 61385 20104 2 1092.578725 547.2931 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 9.75 3731.5 - 939729 - - - 6.4948 - 1.978 0.43 - 250.4 1 2 0 0.0071 10 0 0 0 2.94E+07 2.78E+07 - - - 4.1187 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20105.20105.2 0.000166 18-Aug R.LWGDIYFNPK.T sp|Q15029|U5S1_HUMAN 1 1251.6288 1.08 61386 20105 2 1251.631379 626.8217 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.83 3731.6 - 403055 - - - 2.0533 - 1.749 0.447 - 200.5 1 2 0 0.0026 10 0 0 0 6.77E+06 6.27E+06 - - - 3.9022 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.20114.20114.2 0.0051 14-Aug R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 -1 61395 20114 2 1000.562365 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3732.8 - 136813 - - - 3.0303 - 1.659 0.295 - 180.1 1 2 0 0.003 8 0 0 0 0.00E+00 0.00E+00 - - - 2.7456 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20118.20118.2 0.00329 16-Aug R.GFFGFPGPR[166.11].S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 990.4951 2.11 61398 20118 2 990.496242 496.2548 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3733.2 - 591412 - - - 1.1459 - 1.687 0.42 - 181.9 1 2 0 0.0011 9 0 0 0 4.80E+07 2.28E+07 - - - 3.6557 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.20120.20120.2 1.23 16-Oct R.NLLGLALGR.L sp|Q8N5L8|RP25L_HUMAN 1 925.5709 1.14 61399 20120 2 925.5711 463.7927 Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1 9.75 3733.5 - 632728 - - - 0.215 - 1.843 0.145 - 355.7 1 2 0 0.0002 9 0 0 0 6.27E+07 5.48E+07 - - - 1.8807 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.20124.20124.2 0.00463 20-Aug R.VFSWGFGGYGR.L sp|Q9P258|RCC2_HUMAN 1 1231.5774 1.54 61403 20124 2 1231.578003 616.796 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 8.72 3733.7 - 830731 - - - 0.4547 - 1.699 0.34 - 157.5 1 2 0 0.0006 11 0 0 0 1.04E+07 6.74E+06 - - - 2.9859 1 230117_WJC_METTL3_WT_vs_EV_F07.20125.20125.2 0.00099 14/20 R.VFSWGFGGYGR[166.11].L sp|Q9P258|RCC2_HUMAN 1 1241.5857 1.6 61404 20125 2 1241.585711 621.8001 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 8.72 3733.9 - 486119 - - - -0.0016 - 2.581 0.5 - 624.9 1 2 0 0 11 0 0 0 1.04E+07 6.49E+06 - - - 5.299 0.9938 230117_WJC_METTL3_WT_vs_EV_F07.20129.20129.2 0.0591 18-Oct R.LAEVWMDEFK.N "sp|Q10472|GALT1_HUMAN,sp|Q8IUC8|GLT13_HUMAN,tr|K7EJV8|K7EJV8_HUMAN" 3 1266.5955 0.73 61408 20129 2 1266.600887 634.305 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 4.14 3734.4 - 129038 - - - 4.2847 - 1.442 0.263 - 288.1 1 2 0 0.0054 10 0 0 0 3.43E+06 4.71E+06 - - - 2.0035 1 230117_WJC_METTL3_WT_vs_EV_F07.20134.20134.2 1.42E-09 14/22 K.LYDNLLEQNLIR.V sp|O00231|PSD11_HUMAN 1 1502.8093 1.78 61411 20134 2 1502.809712 752.4119 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3735 - 3.67E+06 - - - 0.2788 - 3.062 0.566 - 822.3 1 2 0 0.0004 12 0 0 0 3.96E+07 2.22E+07 - - - 6.1658 1 230117_WJC_METTL3_WT_vs_EV_F07.20135.20135.2 3.65E-09 15/22 K.LYDNLLEQNLIR[166.11].V sp|O00231|PSD11_HUMAN 1 1512.8176 1.78 61412 20135 2 1512.818538 757.4161 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3735.1 - 2.43E+06 - - - 0.6445 - 3.083 0.596 - 868.8 1 2 0 0.001 12 0 0 0 3.96E+07 2.22E+07 - - - 6.4052 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.20136.20136.2 0.00214 16-Oct K.SLTYLSILR.N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 3 1064.623 1.27 61413 20136 2 1064.626843 533.3188 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 8.46 3735.2 - 2.84E+06 - - - 3.6135 - 1.823 0.437 - 398.6 1 2 0 0.0038 9 0 0 0 1.30E+07 1.03E+07 - - - 4.0047 0.9724 230117_WJC_METTL3_WT_vs_EV_F07.20137.20137.2 0.000318 20-Sep K.FEQLVSIGSSY.N sp|Q9NXV2|KCTD5_HUMAN 1 1228.5976 - 61414 20137 2 1228.599992 615.3061 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4 3735.4 - 2.04E+06 - - - 1.9722 - 1.626 0.487 - 338.5 1 1 0 0.0024 11 0 0 0 - - - - - 3.9523 1 230117_WJC_METTL3_WT_vs_EV_F07.20138.20138.3 1.66E-11 24/76 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 2.55 61415 20138 3 2197.091142 733.3694 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3735.5 - 1.09E+06 - - - 2.2239 - 4.583 0.639 - 680.9 1 2 0 0.0049 20 0 0 0 7.77E+06 3.04E+06 - - - 9.3561 1 230117_WJC_METTL3_WT_vs_EV_F07.20139.20139.2 0.0277 17/28 R.LPLPSPALEYTLGSR.L sp|Q8IU81|I2BP1_HUMAN 1 1612.8825 2.73 61416 20139 2 1612.885235 807.4485 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3735.6 - 1.08E+06 - - - 1.7218 - 2.963 0.486 - 811.4 1 2 0 0.0028 15 0 0 0 4.20E+07 1.54E+07 - - - 5.3002 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.20140.20140.2 0.0354 16-Aug R.GSLITSLLR[166.11].S sp|Q53FA7|QORX_HUMAN 1 968.5894 1.07 61417 20140 2 968.591994 485.302 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3735.8 - 935049 - - - 2.6771 - 1.703 0.291 - 159.1 1 2 0 0.0026 9 0 0 0 6.33E+06 5.89E+06 - - - 2.7297 1 230117_WJC_METTL3_WT_vs_EV_F07.20141.20141.2 3.01E-11 13/20 R.PMEVFMC[160.03]SVLK.R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1339.6338 0.94 61418 20141 2 1339.635173 670.8242 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3735.9 - 895230 - - - 0.9973 - 2.65 0.667 - 675.7 1 1 0 0.0013 11 0 0 0 1.35E+07 1.43E+07 - - - 6.6035 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20142.20142.2 0.118 16-Sep R.LELPADLLR.Q "sp|Q96NU1|SAM11_HUMAN,tr|A0A087WYW1|A0A087WYW1_HUMAN,tr|A0A087WX24|A0A087WX24_HUMAN,tr|A0A087X1J5|A0A087X1J5_HUMAN,tr|A0A087X223|A0A087X223_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|A0A087WXB3|A0A087WXB3_HUMAN,tr|H7C3J6|H7C3J6_HUMAN,tr|A0A087WYU3|A0A087WYU3_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 10 1038.6073 3.83 61419 20142 2 1038.609716 520.3109 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3 4.37 3736 - 810159 - - - 2.2819 - 2.004 0.34 - 285.2 1 2 0 0.0024 9 0 0 0 5.74E+06 1.50E+06 - - - 3.5626 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.20144.20144.2 0.112 16-Aug R.GSLITSLLR.S sp|Q53FA7|QORX_HUMAN 1 958.5811 1.07 61421 20144 2 958.583078 480.2978 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3736.3 - 773476 - - - 2.0311 - 1.638 0.209 - 150.9 1 2 0 0.0019 9 0 0 0 6.33E+06 5.89E+06 - - - 2.0117 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.20149.20149.2 0.000189 13/28 R.LPLPSPALEYTLGSR[166.11].L sp|Q8IU81|I2BP1_HUMAN 1 1622.8907 2.73 61426 20149 2 1622.889525 812.4526 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3736.9 - 2.74E+06 - - - -0.7413 - 1.656 0.456 - 232.4 1 2 0 -0.0012 15 0 0 0 4.20E+07 1.54E+07 - - - 3.6487 0.933 230117_WJC_METTL3_WT_vs_EV_F07.20150.20150.2 6.31 12-Jun K.DFLLSLK.T sp|Q86UP2|KTN1_HUMAN 1 834.4851 1.16 61427 20150 2 834.487643 418.2498 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.84 3737 - 410822 - - - 3.0414 - 1.106 0.033 - 119.8 1 2 0 0.0025 7 0 0 0 2.20E+06 1.90E+06 - - - -0.3968 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20151.20151.2 6.31E-05 24-Sep R.VETPVLPPVLVPR[166.11].H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1424.8631 2.01 61428 20151 2 1424.865249 713.4388 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3737.1 - 397367 - - - 1.5384 - 1.768 0.461 - 171.6 1 2 0 0.0022 13 0 0 0 1.11E+07 5.50E+06 - - - 3.9078 1 230117_WJC_METTL3_WT_vs_EV_F07.20155.20155.2 0.0105 18-Dec R.DAVLLVFANK.Q "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 5 1088.623 1.93 61431 20155 2 1088.625953 545.3188 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 5.84 3737.6 - 3.15E+07 - - - 2.7163 - 2.43 0.489 - 734.3 1 2 0 0.003 10 0 0 0 1.17E+08 6.06E+07 - - - 5.1302 0.9966 230117_WJC_METTL3_WT_vs_EV_F07.20159.20159.2 0.0301 12-Aug R.WIVNLIR.N "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 15 912.5545 0.87 61435 20159 2 912.557573 457.2845 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 9.75 3738 - 3.50E+06 - - - 3.3434 - 1.453 0.239 - 384.8 1 2 0 0.0031 7 0 0 0 3.40E+07 3.93E+07 - - - 1.9892 1 230117_WJC_METTL3_WT_vs_EV_F07.20160.20160.2 1.51E-07 20-Dec R.PMEVFMC[160.03]SVLK[136.11].R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1347.648 0.92 61436 20160 2 1347.650037 674.8313 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3738.1 - 2.50E+06 - - - 1.4841 - 2.482 0.543 - 544.5 1 1 0 0.002 11 0 0 0 1.36E+07 1.48E+07 - - - 5.5102 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.20162.20162.2 0.000131 14-Sep R.YGLEC[160.03]LFR.Y "sp|Q6PKG0|LARP1_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN" 3 1056.5063 0.8 61438 20162 2 1056.510753 529.2604 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 5.99 3738.3 - 1.81E+06 - - - 4.2603 - 1.878 0.36 - 313.1 1 2 0 0.0045 8 0 0 0 6.57E+06 8.24E+06 - - - 3.5992 1 230117_WJC_METTL3_WT_vs_EV_F07.20166.20166.2 2.35E-05 18/30 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 7.14 61442 20166 2 1549.887772 775.9487 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3738.9 - 1.15E+06 - - - 3.2131 - 3.065 0.516 - 1071.2 1 2 0 0.005 16 0 0 0 1.85E+08 2.59E+07 - - - 5.6043 0.9589 230117_WJC_METTL3_WT_vs_EV_F07.20174.20174.2 9.88 12-Apr R.KDLGFSK.L sp|Q9H4L5|OSBL3_HUMAN 1 793.4334 0.23 61450 20174 2 793.435391 397.724 Oxysterol-binding protein-related protein 3 OS=Homo sapiens OX=9606 GN=OSBPL3 PE=1 SV=1 8.59 3739.9 - 372514 - - - 2.5043 - 0.888 0.145 - 41 1 2 0 0.002 7 0 0 0 2.35E+06 1.01E+07 - - - -0.265 1 230117_WJC_METTL3_WT_vs_EV_F07.20176.20176.2 1.91E-06 20-Dec K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 9.27 61451 20176 2 1184.716938 593.3637 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3740.1 - 2.86E+06 - - - 3.4312 - 2.515 0.579 - 611.4 1 2 0 0.0041 11 0 0 0 1.10E+09 1.19E+08 - - - 5.8112 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.20178.20178.2 0.157 12-Jul R.WIVNLIR[166.11].N "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 15 922.5628 0.87 61453 20178 2 922.563326 462.2887 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 9.75 3740.3 - 5.88E+06 - - - 0.5788 - 1.54 0.258 - 277.5 1 2 0 0.0005 7 0 0 0 3.40E+07 3.93E+07 - - - 2.3145 1 230117_WJC_METTL3_WT_vs_EV_F07.20181.20181.2 5.69E-05 20/30 R.ALIAGGGAPEIELALR[166.11].L sp|P50991|TCPD_HUMAN 1 1559.8911 6.93 61456 20181 2 1559.893461 780.9528 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3740.5 - 823326 - - - 1.5379 - 2.996 0.44 - 1427.9 1 2 0 0.0024 16 0 0 0 1.86E+08 2.68E+07 - - - 4.9878 1 230117_WJC_METTL3_WT_vs_EV_F07.20182.20182.2 2.79E-05 18-Nov R.VFYYLVQDLK[136.11].C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1294.7053 0.94 61457 20182 2 1294.708138 648.3599 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3740.6 - 614539 - - - 2.2113 - 2.328 0.524 - 459.1 1 2 0 0.0029 10 0 0 0 5.23E+07 5.56E+07 - - - 5.269 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20183.20183.2 0.000282 20-Oct K.DSLTLVFVETK[136.11].K "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1258.69 -1 61458 20183 2 1258.691232 630.3523 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3740.7 - 612735 - - - 0.9637 - 1.93 0.436 - 392.6 1 2 0 0.0012 11 0 0 0 0.00E+00 0.00E+00 - - - 4.0397 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20185.20185.2 0.000211 18-Sep R.VFYYLVQDLK.C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1286.6911 0.94 61460 20185 2 1286.693888 644.3528 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3740.9 - 586732 - - - 2.1862 - 2.039 0.418 - 283.1 1 2 0 0.0028 10 0 0 0 5.23E+07 5.55E+07 - - - 4.1162 0.999 230117_WJC_METTL3_WT_vs_EV_F07.20187.20187.2 1.1 14-Aug K.TMLTELLR[166.11].G "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 985.5506 1.1 61462 20187 2 985.551599 493.7826 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 5.66 3741.2 - 350831 - - - 1.041 - 1.675 0.245 - 253.7 1 2 0 0.001 8 0 0 0 2.91E+06 2.65E+06 - - - 2.4059 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.20188.20188.2 0.079 16-Sep R.FPVDIFYTK.A "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 5 1128.5855 1.5 61463 20188 2 1128.584813 565.3001 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 5.83 3741.3 - 302989 - - - -0.6513 - 1.663 0.222 - 157.4 1 2 0 -0.0007 9 0 0 0 2.27E+06 1.52E+06 - - - 2.1519 0.8494 230117_WJC_METTL3_WT_vs_EV_F07.20191.20191.2 1.93 Apr-34 R.AAAQVSEAVLAINLLIGK.K "sp|Q96N23|CFA54_HUMAN,tr|A0A1B0GU80|A0A1B0GU80_HUMAN" 2 1780.0458 1.4 61466 20191 2 1780.053 891.0302 Cilia- and flagella-associated protein 54 OS=Homo sapiens OX=9606 GN=CFAP54 PE=2 SV=3 6.05 3741.7 - 0 - - - 4.0252 - 1.105 0.079 - 28.8 9 2 0 0.0072 18 0 0 0 1.89E+06 1.34E+06 - - - -0.5585 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.20194.20194.2 0.0103 16-Aug R.NLLGLALGR[166.11].L sp|Q8N5L8|RP25L_HUMAN 1 935.5792 1.14 61468 20194 2 935.580104 468.7969 Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1 9.75 3742.2 - 1.95E+06 - - - 0.9972 - 1.708 0.187 - 223.8 1 2 0 0.0009 9 0 0 0 6.27E+07 5.48E+07 - - - 1.9706 1 230117_WJC_METTL3_WT_vs_EV_F07.20196.20196.2 0.00111 18-Oct K.YFSSMAEFLK.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1221.574 1.24 61470 20196 2 1221.576896 611.7943 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 3742.4 - 3.48E+06 - - - 2.3732 - 1.932 0.554 - 210 1 2 0 0.0029 10 0 0 0 3.23E+07 2.62E+07 - - - 4.9702 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.20197.20197.2 0.000661 18-Sep R.YVEFNLLYDR.G "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1330.6558 1.19 61471 20197 2 1330.661281 666.3352 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.37 3742.5 - 7.09E+06 - - - 4.1551 - 1.956 0.471 - 267.3 1 2 0 0.0055 10 0 0 0 9.02E+06 7.61E+06 - - - 4.3908 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.20199.20199.3 5.71E-05 15/60 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 3.65 61473 20199 3 1549.886331 517.6349 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3742.7 - 1.47E+06 - - - 2.2834 - 2.583 0.481 - 257.5 1 2 0 0.0035 16 0 0 0 8.62E+06 2.36E+06 - - - 6.3366 0.9942 230117_WJC_METTL3_WT_vs_EV_F07.20201.20201.2 0.00436 12-Aug K.LFFLQVK[136.11].E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 901.5517 0.71 61475 20201 2 901.553382 451.7831 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3743 - 1.04E+06 - - - 1.8934 - 1.298 0.142 - 185.9 1 2 0 0.0017 7 0 0 0 4.75E+06 6.66E+06 - - - 0.9157 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.20202.20202.2 3.73E-05 20-Oct K.TYLQALPYFDR.L "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1385.698 -1 61476 20202 2 1385.697099 693.8563 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 5.5 3743.1 - 1.01E+06 - - - -0.6156 - 1.942 0.371 - 386.1 1 2 0 -0.0009 11 0 0 0 0.00E+00 0.00E+00 - - - 3.5765 0.9958 230117_WJC_METTL3_WT_vs_EV_F07.20206.20206.2 0.367 12-Jul K.LFFLQVK.E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 893.5375 0.71 61480 20206 2 893.53929 447.776 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3743.6 - 587040 - - - 2.0313 - 1.487 0.121 - 150.8 1 2 0 0.0018 7 0 0 0 4.75E+06 6.66E+06 - - - 1.1913 0.9757 230117_WJC_METTL3_WT_vs_EV_F07.20208.20208.2 3.01 12-May K.DFILFTK.K "sp|Q9Y6X9|MORC2_HUMAN,sp|Q86VD1|MORC1_HUMAN" 2 882.4851 1.2 61482 20208 2 882.486046 442.2498 ATPase MORC2 OS=Homo sapiens OX=9606 GN=MORC2 PE=1 SV=2 5.84 3743.9 - 516143 - - - 1.0663 - 1.103 0.072 - 99.6 1 2 0 0.0009 7 0 0 0 1.60E+06 1.33E+06 - - - -0.1169 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20209.20209.2 0.00138 22-Oct R.GLSSLLYGSIPK.A sp|P53007|TXTP_HUMAN 1 1233.6969 0.44 61483 20209 2 1233.69944 617.8557 "Tricarboxylate transport protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A1 PE=1 SV=2" 8.59 3744 - 649505 - - - 2.0678 - 1.606 0.387 - 152.8 1 2 0 0.0026 12 0 0 0 2.03E+06 4.61E+06 - - - 3.1451 1 230117_WJC_METTL3_WT_vs_EV_F07.20211.20211.2 9.90E-08 22-Nov K.C[160.03]PLDPYFIMPDK.C "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 3 1494.6887 2 61485 20211 2 1494.688796 748.3516 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4.21 3744.3 - 333007 - - - 0.0582 - 2.304 0.585 - 359.5 1 2 0 0.0001 12 0 0 0 2.02E+06 1.01E+06 - - - 5.5579 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.20215.20215.2 0.0193 20-Nov R.TLVLLDNLNVR.E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1268.7452 1.22 61488 20215 2 1268.749858 635.3799 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3744.7 - 1.38E+06 - - - 3.643 - 2.235 0.359 - 470.2 1 2 0 0.0046 11 0 0 0 3.75E+07 3.06E+07 - - - 3.8668 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20217.20217.3 0.00164 14/40 R.AALLELWELR[166.11]R[166.11].Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1388.8043 0.62 61490 20217 3 1388.805399 463.942 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.19 3745 - 2.73E+06 - - - 0.7841 - 2.496 0.289 - 442.6 1 2 0 0.0011 11 0 0 0 4.10E+06 6.62E+06 - - - 4.3602 0.999 230117_WJC_METTL3_WT_vs_EV_F07.20218.20218.2 0.00382 14-Sep R.WLLSDYVK.V "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN,tr|C9JZH6|C9JZH6_HUMAN" 3 1022.5437 2.69 61491 20218 2 1022.543871 512.2791 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.83 3745.1 - 2.68E+06 - - - 0.1839 - 1.724 0.267 - 348.3 1 2 0 0.0002 8 0 0 0 8.11E+06 3.02E+06 - - - 2.6556 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.20220.20220.2 0.265 14-Sep R.LLLEDLVK.K "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 941.5797 1.66 61493 20220 2 941.580813 471.7971 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 4.37 3745.4 - 1.46E+06 - - - 1.1459 - 1.564 0.228 - 192.1 1 2 0 0.0011 8 0 0 0 3.12E+06 1.88E+06 - - - 2.0735 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20221.20221.2 2.11E-05 16-Oct R.LTSFITVFK.Y "sp|Q13617|CUL2_HUMAN,tr|Q5T2B5|Q5T2B5_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 3 1054.6063 2.45 61494 20221 2 1054.608646 528.3104 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 8.75 3745.5 - 1.13E+06 - - - 2.2406 - 2.271 0.296 - 254.1 1 2 0 0.0024 9 0 0 0 8.21E+06 3.35E+06 - - - 3.5995 1 230117_WJC_METTL3_WT_vs_EV_F07.20222.20222.3 7.97E-10 23/72 K.LGGSLADSYLDEGFLLDKK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2040.0415 -1 61495 20222 3 2040.044479 681.0211 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.23 3745.6 - 1.12E+06 - - - 1.4416 - 4.41 0.651 - 883.5 1 2 0 0.0029 19 0 0 0 0.00E+00 0.00E+00 - - - 9.4428 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20223.20223.2 0.00387 26-Nov K.IPPPVIMVQNVSFK.Y sp|Q9UG63|ABCF2_HUMAN 1 1567.8796 3.27 61496 20223 2 1567.879741 784.9471 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.75 3745.7 - 945662 - - - 0.0765 - 1.913 0.415 - 288.2 1 2 0 0.0001 14 0 0 0 3.27E+06 9.99E+05 - - - 3.734 0.9953 230117_WJC_METTL3_WT_vs_EV_F07.20224.20224.2 1.98 14-Sep R.LLLEDLVK[136.11].K "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 949.5939 1.66 61497 20224 2 949.595625 475.8042 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 4.37 3745.9 - 933476 - - - 1.7808 - 1.339 0.153 - 172.3 1 2 0 0.0017 8 0 0 0 3.12E+06 1.88E+06 - - - 1.051 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.20244.20244.2 0.0085 14-Aug K.AIFLFVDK[136.11].T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 959.5572 1.3 61516 20244 2 959.557217 480.7859 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3748.3 - 246566 - - - 0.0657 - 1.604 0.328 - 222.6 1 2 0 0.0001 8 0 0 0 6.61E+06 5.09E+06 - - - 2.8886 1 230117_WJC_METTL3_WT_vs_EV_F07.20251.20251.2 0.000755 22-Dec K.LGAIFLEGVTVK.G sp|O60942|MCE1_HUMAN 1 1245.7333 12.76 61521 20251 2 1245.739351 623.8739 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 6 3749.1 - 740721 - - - 4.8774 - 2.462 0.443 - 475 1 2 0 0.0061 12 0 0 0 6.88E+06 5.40E+05 - - - 4.6817 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.20252.20252.2 0.00839 14-Aug K.AIFLFVDK.T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 951.543 1.3 61522 20252 2 951.543284 476.7788 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3749.2 - 547347 - - - 0.3468 - 1.645 0.327 - 208 1 2 0 0.0003 8 0 0 0 6.61E+06 5.09E+06 - - - 2.9573 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.20254.20254.2 0.211 12-Jun R.IIWQFIK.E "sp|P48735|IDHP_HUMAN,tr|H0YL11|H0YL11_HUMAN" 2 946.564 2.7 61524 20254 2 946.565118 474.2893 "Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2" 8.75 3749.4 - 490558 - - - 1.1558 - 1.104 0.335 - 90.4 1 2 0 0.0011 7 0 0 0 5.18E+06 1.92E+06 - - - 1.8285 0.9931 230117_WJC_METTL3_WT_vs_EV_F07.20255.20255.2 2.78 12-Jul R.IIWELIK[136.11].E "sp|O75874|IDHC_HUMAN,tr|C9JLU6|C9JLU6_HUMAN,tr|C9J4N6|C9J4N6_HUMAN,tr|C9JJE5|C9JJE5_HUMAN" 4 921.5779 5.99 61525 20255 2 921.579068 461.7962 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 6 3749.5 - 400579 - - - 1.2782 - 1.459 0.086 - 121.6 2 2 0 0.0012 7 0 0 0 1.77E+07 2.96E+06 - - - 0.7383 0.9947 230117_WJC_METTL3_WT_vs_EV_F07.20257.20257.2 6.50E-06 24-Dec R.GAAGALLVYDITR.R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1318.7245 1.56 61527 20257 2 1318.729944 660.3695 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3749.8 - 234198 - - - 4.1275 - 2.01 0.166 - 399.6 1 2 0 0.0054 13 0 0 0 1.89E+06 1.21E+06 - - - 2.0571 0.9916 230117_WJC_METTL3_WT_vs_EV_F07.20260.20260.2 0.171 18-Jul K.EGLSFLGGLR.S "sp|Q6WKZ4|RFIP1_HUMAN,tr|E7EX40|E7EX40_HUMAN" 2 1047.5713 1.43 61530 20260 2 1047.571204 524.7929 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 6.1 3750.2 - 192112 - - - -0.0869 - 1.359 0.137 - 96 1 2 0 -0.0001 10 0 0 0 1.59E+06 1.12E+06 - - - 0.9091 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20266.20266.2 0.00152 22-Nov K.ALFSLAPEVEVR.V "sp|Q8N3Z3|GTPB8_HUMAN,tr|C9J8V5|C9J8V5_HUMAN,tr|F8WBY6|F8WBY6_HUMAN" 3 1329.7293 1.42 61535 20266 2 1329.731608 665.8719 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.53 3750.9 - 280734 - - - 1.7718 - 2.495 0.416 - 463.4 1 2 0 0.0024 12 0 0 0 4.92E+06 3.47E+06 - - - 4.5185 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20269.20269.2 0.00513 18-Sep R.DIIALNPLYR.E "sp|P36776|LONM_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN" 3 1186.671 3.04 61538 20269 2 1186.671457 594.3428 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 5.84 3751.3 - 347140 - - - 0.3775 - 1.978 0.305 - 298 1 2 0 0.0004 10 0 0 0 3.33E+06 1.09E+06 - - - 3.1975 1 230117_WJC_METTL3_WT_vs_EV_F07.20283.20283.2 0.00102 13/22 R.ALLANALTSALR.L "sp|P57088|TMM33_HUMAN,tr|D6RAA6|D6RAA6_HUMAN" 2 1212.719 1.12 61550 20283 2 1212.723692 607.3668 Transmembrane protein 33 OS=Homo sapiens OX=9606 GN=TMEM33 PE=1 SV=2 9.79 3753 - 4.36E+06 - - - 3.8517 - 2.738 0.433 - 638.2 1 2 0 0.0047 12 0 0 0 1.64E+07 1.46E+07 - - - 4.8879 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.20284.20284.2 0.00325 18/22 R.ALLANALTSALR[166.11].L "sp|P57088|TMM33_HUMAN,tr|D6RAA6|D6RAA6_HUMAN" 2 1222.7273 1.12 61551 20284 2 1222.732462 612.3709 Transmembrane protein 33 OS=Homo sapiens OX=9606 GN=TMEM33 PE=1 SV=2 9.79 3753 - 4.03E+06 - - - 4.2291 - 2.625 0.353 - 1684.4 1 2 0 0.0052 12 0 0 0 1.64E+07 1.46E+07 - - - 4.1859 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20285.20285.2 0.0111 18-Oct R.DLASVQALLR[166.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1094.6323 0.81 61552 20285 2 1094.633531 548.3234 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3753.1 - 2.73E+06 - - - 1.099 - 2.075 0.32 - 328 1 2 0 0.0012 10 0 0 0 1.92E+07 2.37E+07 - - - 3.4417 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.20286.20286.2 0.0123 18-Oct R.DLASVQALLR.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1084.6241 0.81 61553 20286 2 1084.628416 543.3193 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3753.1 - 2.08E+06 - - - 4.018 - 2.006 0.334 - 365 1 2 0 0.0044 10 0 0 0 1.94E+07 2.40E+07 - - - 3.4497 1 230117_WJC_METTL3_WT_vs_EV_F07.20287.20287.2 0.0119 18-Nov R.FC[160.03]IWTESAFR[166.11].K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1325.6102 0.91 61554 20287 2 1325.610928 663.8124 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3753.2 - 2.07E+06 - - - 0.5394 - 2.216 0.496 - 482.7 1 2 0 0.0007 10 0 0 0 1.02E+07 1.11E+07 - - - 4.9253 0.984 230117_WJC_METTL3_WT_vs_EV_F07.20288.20288.2 0.29 12-Jun R.TLLEFLK[136.11].R "sp|Q14232|EI2BA_HUMAN,tr|F5H0D0|F5H0D0_HUMAN,tr|H0YGG4|H0YGG4_HUMAN" 3 870.5306 1.56 61555 20288 2 870.531469 436.2726 Translation initiation factor eIF-2B subunit alpha OS=Homo sapiens OX=9606 GN=EIF2B1 PE=1 SV=1 5.66 3753.2 - 1.88E+06 - - - 0.9925 - 1.238 0.061 - 134.4 1 2 0 0.0009 7 0 0 0 1.63E+07 1.04E+07 - - - 0.1678 1 230117_WJC_METTL3_WT_vs_EV_F07.20290.20290.2 0.0134 18-Nov R.FC[160.03]IWTESAFR.K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1315.6019 0.99 61557 20290 2 1315.603695 658.8082 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3753.4 - 1.40E+06 - - - 1.3317 - 2.254 0.454 - 572.6 1 2 0 0.0018 10 0 0 0 1.10E+07 1.11E+07 - - - 4.6622 1 230117_WJC_METTL3_WT_vs_EV_F07.20291.20291.2 3.12E-09 14/28 L.LVSVSALTLATETVR.S sp|P50991|TCPD_HUMAN 1 1558.893 9.29 61558 20291 2 1558.895313 780.4538 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6 3753.4 - 1.27E+06 - - - 1.469 - 2.824 0.637 - 645.4 1 1 0 0.0023 15 0 0 0 7.00E+06 7.53E+05 - - - 6.2975 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.20293.20293.2 0.00823 18-Jun R.FSDFLGLYEK.L sp|Q13596|SNX1_HUMAN 1 1217.5968 3.4 61560 20293 2 1217.598707 609.8057 Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3 4.37 3753.6 - 869805 - - - 1.5325 - 1.373 0.372 - 69 1 2 0 0.0019 10 0 0 0 2.95E+06 8.67E+05 - - - 2.6728 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20294.20294.2 0.00601 20-Nov R.AFITNIPFDVK[136.11].W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1271.7005 2.59 61561 20294 2 1271.702427 636.8575 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3753.7 - 761605 - - - 1.4964 - 2.003 0.415 - 389.4 1 2 0 0.0019 11 0 0 0 6.80E+08 2.63E+08 - - - 3.9848 1 230117_WJC_METTL3_WT_vs_EV_F07.20297.20297.2 4.25E-06 22-Nov K.FLQDTIEEMALK[136.11].N sp|O95202|LETM1_HUMAN 1 1444.7363 2.54 61564 20297 2 1444.737316 723.3754 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.14 3753.9 - 635787 - - - 0.6908 - 2.437 0.549 - 332.4 1 2 0 0.001 12 0 0 0 1.38E+07 5.42E+06 - - - 5.4394 0.9998 230117_WJC_METTL3_WT_vs_EV_F07.20298.20298.3 3.14E-05 Dec-44 R.LLHLPLSLTALK.L sp|Q9BTT6|LRRC1_HUMAN 1 1317.8384 2.53 61565 20298 3 1317.839635 440.2867 Leucine-rich repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRRC1 PE=1 SV=1 8.76 3754.1 - 633937 - - - 0.9311 - 2.27 0.359 - 283 1 2 0 0.0012 12 0 0 0 2.57E+06 1.02E+06 - - - 4.8145 0.9866 230117_WJC_METTL3_WT_vs_EV_F07.20300.20300.2 0.268 16-Aug R.EPLFLDLPK.S "sp|O60911|CATL2_HUMAN,tr|A0A7P0T983|A0A7P0T983_HUMAN,tr|A0A7P0Z415|A0A7P0Z415_HUMAN" 3 1070.6012 1.37 61567 20300 2 1070.605783 536.3079 Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 SV=2 4.37 3754.2 - 584972 - - - 4.2826 - 1.379 0.184 - 144.7 1 2 0 0.0046 9 0 0 0 1.61E+06 1.18E+06 - - - 1.3283 0.9803 230117_WJC_METTL3_WT_vs_EV_F07.20301.20301.2 0.946 14-Jun K.QDILTIFK[136.11].R "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV8|B0QYV8_HUMAN" 2 984.5735 1.65 61568 20301 2 984.578059 493.294 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3754.3 - 518212 - - - 4.5969 - 1.321 0.178 - 111.4 1 2 0 0.0045 8 0 0 0 1.75E+07 1.06E+07 - - - 1.1939 0.8957 230117_WJC_METTL3_WT_vs_EV_F07.20302.20302.2 0.0252 22-Aug K.LLPELLQPYTER.V sp|Q13057|COASY_HUMAN 1 1470.8082 4.45 61569 20302 2 1471.816713 736.4114 Bifunctional coenzyme A synthase OS=Homo sapiens OX=9606 GN=COASY PE=1 SV=4 4.53 3754.4 - 497279 - - - 685.6659 - 1.854 0.383 - 221 1 2 0 1.0085 12 0 0 0 1.96E+06 4.41E+05 - - - 3.1775 1 230117_WJC_METTL3_WT_vs_EV_F07.20304.20304.2 0.00196 13/20 R.AFITNIPFDVK.W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1263.6863 2.59 61570 20304 2 1263.690117 632.8504 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3754.6 - 4.38E+06 - - - 3.0015 - 2.223 0.473 - 651.5 1 2 0 0.0038 11 0 0 0 6.80E+08 2.63E+08 - - - 4.6945 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20309.20309.2 0.00145 12-Aug R.YGLVFFR[166.11].Q "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN,tr|F6WRY4|F6WRY4_HUMAN" 4 910.494 1.12 61575 20309 2 910.495206 456.2543 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.75 3755 - 799657 - - - 1.2762 - 1.78 0.361 - 282.3 1 2 0 0.0012 7 0 0 0 5.28E+06 4.70E+06 - - - 3.534 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.20311.20311.2 0.00178 26-Nov K.LLTGELLPTDGMIR.K sp|Q9UG63|ABCF2_HUMAN 1 1527.8331 3.37 61577 20311 2 1527.840624 764.9238 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.37 3755.1 - 781638 - - - 4.9475 - 2.211 0.385 - 292.6 1 2 0 0.0076 14 0 0 0 7.71E+06 2.29E+06 - - - 3.8733 0.999 230117_WJC_METTL3_WT_vs_EV_F07.20313.20313.2 0.0952 12-Aug R.YGLVFFR.Q "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN,tr|F6WRY4|F6WRY4_HUMAN" 4 900.4858 1.11 61579 20313 2 900.486075 451.2502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.75 3755.3 - 623618 - - - 0.3343 - 1.719 0.259 - 285.4 1 2 0 0.0003 7 0 0 0 5.28E+06 4.76E+06 - - - 2.6704 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.20315.20315.2 0.182 20-May R.VLPSIVNEVLK[136.11].S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1217.7475 -1 61581 20315 2 1217.748142 609.881 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3755.4 - 615073 - - - 0.5477 - 1.277 0.305 - 51.7 6 2 0 0.0007 11 0 0 0 0.00E+00 0.00E+00 - - - 1.6074 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20316.20316.2 0.0146 14-Aug K.EILIPVFK[136.11].N sp|P53396|ACLY_HUMAN 1 965.6041 1.32 61582 20316 2 965.605331 483.8093 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3755.5 - 612108 - - - 1.2697 - 1.573 0.406 - 213.8 1 2 0 0.0012 8 0 0 0 3.75E+07 2.84E+07 - - - 3.4055 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20319.20319.2 0.307 26-Nov K.ALLAVIGADSVTLK[136.11].N sp|Q9NYH9|UTP6_HUMAN 1 1377.8323 1.5 61585 20319 2 1377.835181 689.9234 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3755.6 - 397121 - - - 2.1149 - 2.443 0.253 - 434.9 1 2 0 0.0029 14 0 0 0 3.20E+06 2.13E+06 - - - 3.1503 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.20320.20320.2 0.0426 16-Jun R.LELPADLLR[166.11].Q "sp|Q96NU1|SAM11_HUMAN,tr|A0A087WYW1|A0A087WYW1_HUMAN,tr|A0A087WX24|A0A087WX24_HUMAN,tr|A0A087X1J5|A0A087X1J5_HUMAN,tr|A0A087X223|A0A087X223_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|A0A087WXB3|A0A087WXB3_HUMAN,tr|H7C3J6|H7C3J6_HUMAN,tr|A0A087WYU3|A0A087WYU3_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 10 1048.6156 4.62 61586 20320 2 1048.617271 525.3151 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3 4.37 3755.7 - 359613 - - - 1.5783 - 1.292 0.294 - 87.8 1 2 0 0.0017 9 0 0 0 7.35E+06 1.59E+06 - - - 1.9531 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.20324.20324.2 0.121 18-Aug R.LTTLELLEVR[166.11].R "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1195.7052 0.67 61589 20324 2 1195.706134 598.8599 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.53 3756.2 - 5.16E+06 - - - 0.8154 - 1.904 0.28 - 264.9 1 2 0 0.001 10 0 0 0 2.16E+07 3.24E+07 - - - 2.9063 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20328.20328.2 0.0111 18-Sep K.LGLFPSNFVK.E sp|Q9Y5K6|CD2AP_HUMAN 1 1120.6281 1.57 61593 20328 2 1120.629889 561.3213 CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1 8.75 3756.6 - 1.17E+06 - - - 1.6134 - 1.825 0.344 - 199.1 1 2 0 0.0018 10 0 0 0 6.36E+06 4.05E+06 - - - 3.2604 1 230117_WJC_METTL3_WT_vs_EV_F07.20329.20329.2 1.62E-07 20-Dec R.FSYLAVIEGAK[136.11].F "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 1204.6583 1.59 61594 20329 2 1204.660298 603.3364 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 6 3756.7 - 1.10E+06 - - - 1.6378 - 2.448 0.603 - 428.5 1 2 0 0.002 11 0 0 0 7.97E+06 5.01E+06 - - - 5.9161 1 230117_WJC_METTL3_WT_vs_EV_F07.20334.20334.2 4.06E-07 24-Dec R.PVGTSLFLQTALR[166.11].G sp|Q9H9S5|FKRP_HUMAN 1 1411.8063 0.73 61599 20334 2 1411.808642 706.9104 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 10.18 3757.3 - 423446 - - - 1.6801 - 2.185 0.613 - 320.6 1 1 0 0.0024 13 0 0 0 1.44E+06 1.96E+06 - - - 5.5739 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.20336.20336.2 0.102 12-Jul R.WFVFDAR.R sp|Q9UPU7|TBD2B_HUMAN 1 939.4603 1.58 61601 20336 2 939.461223 470.7374 TBC1 domain family member 2B OS=Homo sapiens OX=9606 GN=TBC1D2B PE=1 SV=2 5.84 3757.5 - 384199 - - - 0.9963 - 1.197 0.274 - 134 1 2 0 0.0009 7 0 0 0 1.51E+06 9.56E+05 - - - 1.6342 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.20340.20340.2 0.09 14-Aug K.EILIPVFK.N sp|P53396|ACLY_HUMAN 1 957.5899 1.32 61604 20340 2 957.591037 479.8022 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3758 - 3.52E+06 - - - 1.1821 - 1.633 0.298 - 222.1 1 2 0 0.0011 8 0 0 0 3.75E+07 2.84E+07 - - - 2.7208 1 230117_WJC_METTL3_WT_vs_EV_F07.20343.20343.2 9.28E-06 22-Oct R.LFTNFSGADLLK.L "sp|Q12800|TFCP2_HUMAN,tr|F8VWL0|F8VWL0_HUMAN" 2 1324.7027 2.2 61606 20343 2 1324.704702 663.3586 Alpha-globin transcription factor CP2 OS=Homo sapiens OX=9606 GN=TFCP2 PE=1 SV=2 5.84 3758.3 - 1.63E+06 - - - 1.509 - 2.155 0.495 - 250.2 1 2 0 0.002 12 0 0 0 6.07E+06 2.76E+06 - - - 4.7166 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20348.20348.2 0.021 16-Oct R.ALQLLYDLR.Y "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1103.6339 1.08 61611 20348 2 1103.634737 552.8242 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.88 3758.8 - 1.18E+06 - - - 0.7629 - 2.146 0.291 - 464.5 1 2 0 0.0008 9 0 0 0 5.37E+06 4.98E+06 - - - 3.3992 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20350.20350.2 4.59E-05 20-Nov R.ELGLGLGLGLK.E "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 1068.6543 1.09 61613 20350 2 1068.657873 535.3344 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 6.1 3759.1 - 1.02E+06 - - - 3.3472 - 2.182 0.45 - 286.8 1 2 0 0.0036 11 0 0 0 2.94E+06 2.69E+06 - - - 4.4743 0.9958 230117_WJC_METTL3_WT_vs_EV_F07.20352.20352.2 0.412 12-May R.DVFLMLK.K "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 864.4779 1 61615 20352 2 864.478887 433.2462 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 5.84 3759.3 - 667489 - - - 1.129 - 1.303 0.166 - 90 1 2 0 0.001 7 0 0 0 2.51E+06 2.52E+06 - - - 1.1054 1 230117_WJC_METTL3_WT_vs_EV_F07.20353.20353.2 0.000126 13/24 K.ILTFDQLALDSPK.G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1459.7922 0.76 61616 20353 2 1459.79022 730.9034 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3759.4 - 646916 - - - -1.3879 - 2.754 0.559 - 635.5 1 2 0 -0.002 13 0 0 0 1.29E+08 1.71E+08 - - - 5.7692 0.9952 230117_WJC_METTL3_WT_vs_EV_F07.20354.20354.2 0.768 12-Jun R.DVFLMLK[136.11].K "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 872.4921 1 61617 20354 2 872.493401 437.2533 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 5.84 3759.6 - 564619 - - - 1.4785 - 1.279 0.16 - 114.5 1 2 0 0.0013 7 0 0 0 2.51E+06 2.52E+06 - - - 1.0021 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.20356.20356.2 0.00511 20-Aug R.LLTGWMPTAIR.G "sp|Q12769|NU160_HUMAN,tr|E9PR16|E9PR16_HUMAN,tr|G3V198|G3V198_HUMAN" 3 1257.6904 0.56 61619 20356 2 1257.691792 629.8525 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 9.75 3759.8 - 490770 - - - 1.1354 - 1.583 0.296 - 204.6 1 2 0 0.0014 11 0 0 0 1.53E+07 2.74E+07 - - - 2.4694 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.20358.20358.3 0.00126 19/48 R.WLPLGLGLNHLGK.G "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1416.8242 2.2 61621 20358 3 1416.826094 473.282 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 8.76 3760.1 - 393177 - - - 1.3686 - 2.973 0.392 - 492.3 1 2 0 0.0019 13 0 0 0 3.98E+06 1.81E+06 - - - 5.864 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.20365.20365.2 2.75 14-Jul R.LLLTPWVK[136.11].F sp|Q14152|EIF3A_HUMAN 1 976.6201 0.94 61627 20365 2 976.622247 489.3173 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.75 3760.9 - 4.50E+06 - - - 2.2097 - 1.513 0.12 - 111.6 1 2 0 0.0022 8 0 0 0 1.80E+07 1.90E+07 - - - 1.1755 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.20366.20366.2 0.079 20-Dec R.VLPSIVNEVLK.S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1209.7333 1.36 61628 20366 2 1209.737588 605.8739 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3761 - 2.03E+06 - - - 3.5652 - 2.046 0.41 - 438.8 1 2 0 0.0043 11 0 0 0 1.38E+08 1.01E+08 - - - 4.0045 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20367.20367.2 0.00149 16-Nov K.LGFMSAFVK[136.11].A "sp|P36957|ODO2_HUMAN,tr|Q86SW4|Q86SW4_HUMAN" 2 1006.5401 0.75 61629 20367 2 1006.541552 504.2773 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 8.75 3761.1 - 1.70E+06 - - - 1.4187 - 2.05 0.361 - 295 1 2 0 0.0014 9 0 0 0 4.68E+06 6.22E+06 - - - 3.7836 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20370.20370.2 2.60E-05 16-Sep K.MTILQTYFR[166.11].Q sp|O75348|VATG1_HUMAN 1 1181.6142 1.02 61632 20370 2 1181.614565 591.8144 V-type proton ATPase subunit G 1 OS=Homo sapiens OX=9606 GN=ATP6V1G1 PE=1 SV=3 8.5 3761.5 - 818567 - - - 0.2793 - 2.203 0.38 - 248.8 1 2 0 0.0003 9 0 0 0 7.79E+06 7.61E+06 - - - 4.1326 1 230117_WJC_METTL3_WT_vs_EV_F07.20378.20378.2 3.42E-06 13/28 K.ELVGPPLAETVFTPK.T sp|P49792|RBP2_HUMAN 1 1596.8763 2.78 61640 20378 2 1596.877886 799.4454 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3762.5 - 275836 - - - 0.9869 - 2.027 0.516 - 487.5 1 2 0 0.0016 15 0 0 0 1.54E+07 5.56E+06 - - - 4.5888 0.9551 230117_WJC_METTL3_WT_vs_EV_F07.20379.20379.2 4.38 18-Jul K.MPETDFLIIR.T "sp|Q8IZX4|TAF1L_HUMAN,sp|P21675|TAF1_HUMAN,tr|A0A804HK58|A0A804HK58_HUMAN,tr|A0A804HHS0|A0A804HHS0_HUMAN,tr|A0A804HIY8|A0A804HIY8_HUMAN,tr|A0A804HIC2|A0A804HIC2_HUMAN" 6 1233.6427 0.09 61641 20379 2 1233.644149 617.8286 Transcription initiation factor TFIID subunit 1-like OS=Homo sapiens OX=9606 GN=TAF1L PE=1 SV=1 4.37 3762.6 - 179837 - - - 1.1381 - 1.009 0.074 - 58 2 2 0 0.0014 10 0 0 0 1.45E+06 1.65E+07 - - - -0.5223 1 230117_WJC_METTL3_WT_vs_EV_F07.20384.20384.2 0.00443 14/20 R.IPDQLVILDMK.H "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1283.7159 1.32 61644 20384 2 1283.717252 642.8652 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.21 3763.3 - 1.86E+06 - - - 1.0454 - 3.027 0.45 - 937.9 1 2 0 0.0013 11 0 0 0 3.98E+07 3.00E+07 - - - 5.3605 1 230117_WJC_METTL3_WT_vs_EV_F07.20385.20385.2 0.000107 16/20 R.IPDQLVILDMK[136.11].H "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1291.7301 1.32 61645 20385 2 1291.730288 646.8723 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.21 3763.4 - 1.56E+06 - - - 0.1378 - 3.16 0.485 - 1255.2 1 2 0 0.0002 11 0 0 0 3.98E+07 3.00E+07 - - - 5.7357 0.995 230117_WJC_METTL3_WT_vs_EV_F07.20389.20389.2 0.553 12-Aug R.FVFLLDR.G sp|Q13045|FLII_HUMAN 1 908.512 1.61 61649 20389 2 908.513695 455.2633 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3763.9 - 1.10E+06 - - - 1.8778 - 1.61 0.065 - 248.3 1 2 0 0.0017 7 0 0 0 1.41E+07 8.74E+06 - - - 1.0295 0.9927 230117_WJC_METTL3_WT_vs_EV_F07.20391.20391.2 0.0299 12-Jul R.FVFLLDR[166.11].G sp|Q13045|FLII_HUMAN 1 918.5203 1.61 61651 20391 2 918.522021 460.2674 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3764.2 - 765270 - - - 1.9183 - 1.466 0.068 - 198.3 1 2 0 0.0018 7 0 0 0 1.41E+07 8.74E+06 - - - 0.7548 0.9649 230117_WJC_METTL3_WT_vs_EV_F07.20393.20393.2 0.00103 22-Oct R.NVYPEEMIVALR.E sp|Q5VT52|RPRD2_HUMAN 1 1432.7384 5.53 61653 20393 2 1432.730893 717.3765 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3764.4 - 703720 - - - -5.2647 - 1.803 0.256 - 290.6 1 2 0 -0.0075 12 0 0 0 8.22E+06 1.49E+06 - - - 2.4804 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20395.20395.2 0.000694 13/18 K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.62 61655 20395 2 1168.708373 585.3606 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3764.7 - 640844 - - - 1.4101 - 2.355 0.392 - 453.9 1 2 0 0.0016 10 0 0 0 2.32E+09 1.43E+09 - - - 4.3267 1 230117_WJC_METTL3_WT_vs_EV_F07.20398.20398.2 6.10E-06 20-Oct K.IVFAAGNFWGR.T sp|P04181|OAT_HUMAN 1 1236.6404 0.57 61658 20398 2 1236.643724 619.3275 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 9.75 3765.1 - 517851 - - - 2.7065 - 2.135 0.513 - 325.4 1 2 0 0.0033 11 0 0 0 6.38E+06 1.12E+07 - - - 4.8808 1 230117_WJC_METTL3_WT_vs_EV_F07.20399.20399.2 2.49E-12 18/36 R.YEGILYTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2100.0627 -1 61659 20399 2 2100.063849 1051.0386 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3765.2 - 515846 - - - 0.5628 - 3.656 0.703 - 914.1 1 2 0 0.0012 19 0 0 0 0.00E+00 0.00E+00 - - - 7.4202 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.20400.20400.2 0.012 13/24 R.LAALPNVYEVISK[136.11].S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1423.8166 -1 61660 20400 2 1423.814979 712.9156 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3765.4 - 354100 - - - -1.1504 - 2.344 0.345 - 443.9 1 2 0 -0.0016 13 0 0 0 0.00E+00 0.00E+00 - - - 3.775 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.20401.20401.2 0.00137 16-Oct K.FPEILATLR.G sp|P54198|HIRA_HUMAN 1 1058.6124 2.31 61661 20401 2 1058.616813 530.3135 Protein HIRA OS=Homo sapiens OX=9606 GN=HIRA PE=1 SV=2 6 3765.5 - 341612 - - - 4.1394 - 2.132 0.361 - 365.8 1 2 0 0.0044 9 0 0 0 4.79E+06 2.07E+06 - - - 3.8962 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20408.20408.2 0.0178 14-Sep K.VNLAELFK.G sp|P30044|PRDX5_HUMAN 1 932.5331 2.09 61667 20408 2 932.532993 467.2738 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.97 3766.3 - 2.28E+07 - - - -0.134 - 2.016 0.348 - 280.9 1 2 0 -0.0001 8 0 0 0 1.05E+08 5.02E+07 - - - 3.7258 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.20409.20409.2 0.00304 14-Jul K.VNLAELFK[136.11].G sp|P30044|PRDX5_HUMAN 1 940.5473 2.09 61668 20409 2 940.547147 471.2809 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.97 3766.4 - 1.06E+07 - - - -0.1818 - 1.792 0.354 - 135.9 1 2 0 -0.0002 8 0 0 0 1.05E+08 5.02E+07 - - - 3.4149 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20410.20410.2 0.000193 14-Aug R.DWVLNEFR.S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1077.5243 1.21 61669 20410 2 1077.524908 539.7694 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3766.4 - 9.40E+06 - - - 0.5234 - 1.892 0.389 - 362.7 1 2 0 0.0006 8 0 0 0 3.73E+07 3.09E+07 - - - 3.8371 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.20411.20411.2 1.98E-05 14-Aug R.DWVLNEFR[166.11].S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1087.5326 1.21 61670 20411 2 1087.532971 544.7736 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3766.5 - 8.42E+06 - - - 0.3283 - 1.778 0.314 - 350.6 1 2 0 0.0004 8 0 0 0 3.73E+07 3.09E+07 - - - 3.0957 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.20414.20414.2 0.0644 12-Jul K.YLFTLIR.A sp|P57740|NU107_HUMAN 1 924.5433 0.48 61673 20414 2 924.544492 463.2789 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 8.75 3766.7 - 2.30E+06 - - - 1.3012 - 1.395 0.177 - 189.3 1 2 0 0.0012 7 0 0 0 7.88E+06 1.64E+07 - - - 1.4027 1 230117_WJC_METTL3_WT_vs_EV_F07.20418.20418.2 4.52E-06 14/26 K.LLAESVTEVEIFGK.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1533.829 -1 61677 20418 2 1533.827847 767.9218 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 3767.2 - 1.44E+06 - - - -0.7687 - 2.649 0.485 - 580.2 1 2 0 -0.0012 14 0 0 0 0.00E+00 0.00E+00 - - - 5.0675 0.9797 230117_WJC_METTL3_WT_vs_EV_F07.20421.20421.2 1.1 14-Jun R.LFSWLVNR[166.11].L "sp|O43795|MYO1B_HUMAN,sp|Q8WXR4|MYO3B_HUMAN,tr|F5H2J1|F5H2J1_HUMAN,tr|A0A0U1RRI3|A0A0U1RRI3_HUMAN,tr|E9PDF6|E9PDF6_HUMAN" 5 1043.5792 0.76 61680 20421 2 1043.581143 522.7969 Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3 9.75 3767.6 - 1.26E+06 - - - 1.8897 - 1.278 0.035 - 74.2 1 2 0 0.002 8 0 0 0 3.55E+06 4.69E+06 - - - 0.0387 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20423.20423.2 1.75E-05 18-Sep K.NGFLLDGFPR.T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1134.5822 3.9 61682 20423 2 1134.584514 568.2984 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3767.8 - 1.15E+06 - - - 2.0448 - 1.848 0.468 - 332.3 1 2 0 0.0023 10 0 0 0 1.17E+07 3.00E+06 - - - 4.2111 0.9106 230117_WJC_METTL3_WT_vs_EV_F07.20427.20427.2 0.355 12-Jun R.IWPLYLR[166.11].F sp|Q9HCS7|SYF1_HUMAN 1 969.5675 1.49 61685 20427 2 969.564233 485.791 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 8.75 3768.3 - 471375 - - - -3.4139 - 1.253 0.121 - 116.6 1 2 0 -0.0033 7 0 0 0 4.29E+06 2.87E+06 - - - 0.6483 1 230117_WJC_METTL3_WT_vs_EV_F07.20428.20428.2 7.87E-05 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 1995.19 61686 20428 2 1603.764216 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3768.3 - 5.03E+06 - - - 0.1721 - 1.876 0.554 - 186.2 1 2 0 0.0003 12 0 0 0 1.58E+09 7.90E+05 - - - 4.7881 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.20430.20430.2 0.277 14-Jul R.YLIYDIIK.F sp|O60942|MCE1_HUMAN 1 1039.5954 12.23 61688 20430 2 1039.595832 520.805 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 5.83 3768.5 - 1.23E+06 - - - 0.4309 - 1.249 0.271 - 158.9 1 2 0 0.0004 8 0 0 0 5.49E+06 4.49E+05 - - - 1.713 0.883 230117_WJC_METTL3_WT_vs_EV_F07.20431.20431.2 0.00154 18-Aug N.FAPEFELLAR.M "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1191.6288 -1 61689 20431 2 1191.633261 596.8217 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 4.53 3768.6 - 1.18E+06 - - - 3.7361 - 1.524 0.384 - 134.8 1 1 0 0.0045 10 0 0 0 0.00E+00 0.00E+00 - - - 3.0519 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.20433.20433.2 0.0097 20-Dec R.LEYC[160.03]EALAMLR.E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1367.6577 1.47 61691 20433 2 1367.65677 684.8361 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3768.8 - 1.11E+06 - - - -0.7114 - 2.306 0.131 - 583 1 2 0 -0.001 11 0 0 0 5.43E+06 3.70E+06 - - - 2.2685 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20440.20440.3 0.0238 Oct-36 K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 -1 61698 20440 3 1168.70603 390.5762 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3769.5 - 178334 - - - -0.5947 - 2.064 0.362 - 113.1 1 2 0 -0.0007 10 0 0 0 0.00E+00 0.00E+00 - - - 4.692 1 230117_WJC_METTL3_WT_vs_EV_F07.20449.20449.3 2.21E-05 18/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 1680.33 61706 20449 3 1603.762339 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3770.6 - 1.16E+07 - - - -0.9983 - 2.757 0.591 - 505.3 1 2 0 -0.0016 12 0 0 0 1.12E+08 6.67E+04 - - - 7.9397 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20450.20450.2 0.0129 18-Nov R.VDILDPALLR.S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1123.6601 1.97 61707 20450 2 1123.660291 562.8373 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3770.7 - 8.69E+06 - - - 0.1611 - 2.379 0.369 - 385.7 1 2 0 0.0002 10 0 0 0 9.27E+07 4.69E+07 - - - 4.1855 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.20451.20451.2 0.000264 22-Dec R.GNSIIMLEALER.V "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1344.7071 0.93 61708 20451 2 1344.704788 673.3608 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3770.7 - 6.64E+06 - - - -1.7461 - 2.335 0.437 - 598.6 1 2 0 -0.0023 12 0 0 0 1.32E+07 1.42E+07 - - - 4.4992 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20453.20453.2 0.0002 18-Sep R.TLVEDLFADK.H "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1149.5918 0.99 61710 20453 2 1149.594023 575.8032 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.03 3770.9 - 4.47E+06 - - - 1.9729 - 1.786 0.382 - 181.9 1 2 0 0.0023 10 0 0 0 1.37E+07 1.39E+07 - - - 3.4806 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20454.20454.2 0.0409 18-Oct R.VDILDPALLR[166.11].S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1133.6684 1.97 61711 20454 2 1133.668829 567.8415 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3770.9 - 4.17E+06 - - - 0.3961 - 2.133 0.343 - 320.4 1 2 0 0.0004 10 0 0 0 9.27E+07 4.69E+07 - - - 3.6888 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.20455.20455.3 0.00536 Oct-36 K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.15 61712 20455 3 1176.718 393.2476 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3771.1 - 2.89E+06 - - - -2.4857 - 2.007 0.338 - 116.7 1 2 0 -0.0029 10 0 0 0 4.69E+06 4.10E+06 - - - 4.3421 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20458.20458.2 7.48E-06 22-Oct R.LLVFGGMVEYGK.Y "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 1311.6897 -1 61715 20458 2 1311.691703 656.8521 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 6 3771.4 - 1.44E+06 - - - 1.5308 - 1.829 0.429 - 268.7 1 2 0 0.002 12 0 0 0 0.00E+00 0.00E+00 - - - 3.7976 1 230117_WJC_METTL3_WT_vs_EV_F07.20462.20462.2 7.50E-08 22-Dec R.GYELLFQPEVVR.L "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A804HJM1|A0A804HJM1_HUMAN,tr|A0A804HK15|A0A804HK15_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN,tr|A0A804HIL4|A0A804HIL4_HUMAN" 8 1448.7664 8.69 61719 20462 2 1448.759077 725.3905 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 4.53 3771.9 - 1.01E+06 - - - -5.0312 - 2.446 0.572 - 643.8 1 2 0 -0.0073 12 0 0 0 3.09E+06 3.55E+05 - - - 5.617 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.20463.20463.2 0.00179 16-Aug R.DSVVLSLLK[136.11].Q sp|O43264|ZW10_HUMAN 1 980.5997 1.21 61720 20463 2 980.597708 491.3072 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 5.84 3772.1 - 615328 - - - -2.0804 - 1.608 0.368 - 167.8 1 2 0 -0.002 9 0 0 0 2.70E+06 2.24E+06 - - - 3.1326 0.995 230117_WJC_METTL3_WT_vs_EV_F07.20471.20471.2 0.000588 18-Jun K.DFLLQQTMLR[166.11].V sp|Q04760|LGUL_HUMAN 1 1273.6728 1.2 61726 20471 2 1273.669029 637.8437 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 5.84 3772.8 - 385440 - - - -2.9709 - 1.494 0.403 - 164.4 1 2 0 -0.0038 10 0 0 0 9.31E+06 7.76E+06 - - - 3.137 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20473.20473.2 0.00936 18-Oct R.LSDYLFTLAR.Y "sp|Q96EY8|MMAB_HUMAN,tr|S4R3P5|S4R3P5_HUMAN" 2 1197.6394 2.89 61728 20473 2 1197.638963 599.827 Corrinoid adenosyltransferase OS=Homo sapiens OX=9606 GN=MMAB PE=1 SV=1 5.84 3772.9 - 0 - - - -0.3432 - 2.158 0.412 - 347.5 1 2 0 -0.0004 10 0 0 0 5.17E+06 1.79E+06 - - - 4.2309 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.20474.20474.2 0.0677 14-Aug R.FDILC[160.03]VVR.D "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1020.5426 1.23 61729 20474 2 1020.543679 511.2786 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 5.83 3772.9 - 0 - - - 1.021 - 1.754 0.263 - 235.6 1 2 0 0.001 8 0 0 0 7.79E+06 6.31E+06 - - - 2.6779 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20476.20476.2 0.0163 18-Jun K.NGFLLDGFPR[166.11].T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1144.5905 2.52 61731 20476 2 1144.592561 573.3025 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3773 - 433861 - - - 1.8321 - 1.573 0.368 - 143.2 1 2 0 0.0021 10 0 0 0 1.95E+07 7.75E+06 - - - 3.0228 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.20477.20477.2 0.0153 24-Jun R.LAAVALINAAIQK[136.11].G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1302.8115 -1 61732 20477 2 1302.810923 652.413 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3773.1 - 0 - - - -0.4214 - 1.462 0.345 - 115 1 2 0 -0.0005 13 0 0 0 0.00E+00 0.00E+00 - - - 2.5638 0.8868 230117_WJC_METTL3_WT_vs_EV_F07.20478.20478.2 2.11 12-May R.EFALWLK.D "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 905.5011 -1 61733 20478 2 905.49861 453.7578 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 6.1 3773.1 - 0 - - - -2.7388 - 1.104 0.112 - 107.9 1 2 0 -0.0025 7 0 0 0 0.00E+00 0.00E+00 - - - 0.181 1 230117_WJC_METTL3_WT_vs_EV_F07.20486.20486.2 0.00183 14/22 K.TVLLLADQMISR.L "sp|P48730|KC1D_HUMAN,sp|P49674|KC1E_HUMAN,tr|B0QY36|B0QY36_HUMAN,tr|B0QY34|B0QY34_HUMAN,tr|H7BYT1|H7BYT1_HUMAN,tr|J3QQI9|J3QQI9_HUMAN,tr|A0A669KBC0|A0A669KBC0_HUMAN,tr|H0Y645|H0Y645_HUMAN,tr|B0QY35|B0QY35_HUMAN,tr|H0Y2N6|H0Y2N6_HUMAN" 10 1358.7592 1.7 61739 20486 2 1358.759433 680.3869 Casein kinase I isoform delta OS=Homo sapiens OX=9606 GN=CSNK1D PE=1 SV=2 5.5 3774.1 - 1.51E+06 - - - 0.1921 - 2.932 0.48 - 864.9 1 2 0 0.0003 12 0 0 0 5.27E+06 3.10E+06 - - - 5.4165 0.8956 230117_WJC_METTL3_WT_vs_EV_F07.20488.20488.2 0.0843 16-Aug K.GPLQSVQVF.G "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 973.5233 - 61741 20488 2 973.52429 487.7689 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 5.52 3774.4 - 1.40E+06 - - - 1.0354 - 1.538 0.235 - 179.1 1 1 0 0.001 9 0 0 0 - - - - - 2.0218 1 230117_WJC_METTL3_WT_vs_EV_F07.20490.20490.2 3.07E-07 17/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 85.96 61743 20490 2 1343.610872 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3774.6 - 1.40E+06 - - - -0.4391 - 2.873 0.53 - 1145.3 1 1 0 -0.0006 10 0 0 0 7.41E+06 8.62E+04 - - - 5.9012 1 230117_WJC_METTL3_WT_vs_EV_F07.20493.20493.2 7.17E-06 24-Nov R.TLVSGLLLEDSVR.V sp|A0A2Z4LIS9|FXO3B_HUMAN 1 1400.7875 2.47 61746 20493 2 1400.785161 701.401 Forkhead box protein O3B OS=Homo sapiens OX=9606 GN=FOXO3B PE=1 SV=1 4.37 3775 - 1.04E+06 - - - -1.6662 - 2.702 0.525 - 357.4 1 2 0 -0.0023 13 0 0 0 3.03E+06 1.23E+06 - - - 5.469 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.20494.20494.2 0.00377 22-Dec K.TVLLLADQMISR[166.11].L "sp|P48730|KC1D_HUMAN,sp|P49674|KC1E_HUMAN,tr|B0QY36|B0QY36_HUMAN,tr|B0QY34|B0QY34_HUMAN,tr|H7BYT1|H7BYT1_HUMAN,tr|J3QQI9|J3QQI9_HUMAN,tr|A0A669KBC0|A0A669KBC0_HUMAN,tr|H0Y645|H0Y645_HUMAN,tr|B0QY35|B0QY35_HUMAN,tr|H0Y2N6|H0Y2N6_HUMAN" 10 1368.7674 -1 61747 20494 2 1368.765386 685.391 Casein kinase I isoform delta OS=Homo sapiens OX=9606 GN=CSNK1D PE=1 SV=2 5.5 3775.2 - 963236 - - - -1.5021 - 2.532 0.366 - 480.9 1 2 0 -0.0021 12 0 0 0 0.00E+00 0.00E+00 - - - 4.188 0.9831 230117_WJC_METTL3_WT_vs_EV_F07.20496.20496.2 0.00738 24-Nov R.LAAVALINAAIQK.G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1294.7973 1.06 61749 20496 2 1294.794999 648.4059 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3775.4 - 634469 - - - -1.7555 - 1.468 0.155 - 271 1 2 0 -0.0023 13 0 0 0 3.80E+06 3.59E+06 - - - 1.1704 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.20498.20498.2 0.000431 22-Sep R.IMVANIEEVLQR.G "sp|O75396|SC22B_HUMAN,tr|A0A087X1A9|A0A087X1A9_HUMAN" 2 1413.765 -1 61751 20498 2 1413.766637 707.8898 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 4.53 3775.7 - 438366 - - - 1.1685 - 2.089 0.093 - 270.8 2 2 0 0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 1.5313 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20505.20505.2 0.168 24-Nov R.VDLNEEETILIIR.R "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A0U1RQE1|A0A0U1RQE1_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A0U1RQZ9|A0A0U1RQZ9_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8YCY3|A0A2R8YCY3_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YDA1|A0A2R8YDA1_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8YFV8|A0A2R8YFV8_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A2R8Y4R6|A0A2R8Y4R6_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 25 1555.8457 -1 61757 20505 2 1555.847306 778.9301 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4 3776.7 - 246125 - - - 1.0078 - 1.691 0.365 - 356.5 1 2 0 0.0016 13 0 0 0 0.00E+00 0.00E+00 - - - 3.0846 0.988 230117_WJC_METTL3_WT_vs_EV_F07.20509.20509.2 1.59 12-Jul K.LWDLYLR[166.11].T "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 987.5417 2.04 61761 20509 2 987.541433 494.7781 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.84 3777.2 - 1.14E+06 - - - -0.2926 - 1.399 0.085 - 182.1 1 2 0 -0.0003 7 0 0 0 6.20E+06 3.04E+06 - - - 0.7326 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.20511.20511.2 0.0971 14-Jul R.NLAIFDLR.N sp|Q9NXC5|MIO_HUMAN 1 960.5393 -1 61763 20511 2 960.539203 481.2769 GATOR complex protein MIOS OS=Homo sapiens OX=9606 GN=MIOS PE=1 SV=2 5.84 3777.4 - 830547 - - - -0.0656 - 1.383 0.281 - 144.9 2 2 0 -0.0001 8 0 0 0 0.00E+00 0.00E+00 - - - 1.9599 1 230117_WJC_METTL3_WT_vs_EV_F07.20513.20513.2 0.000531 14/22 K.GAVEALAAALAH.L sp|Q9NR30|DDX21_HUMAN 1 1092.5928 - 61765 20513 2 1092.587919 547.3037 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.24 3777.7 - 733603 - - - -4.4289 - 2.915 0.483 - 635.4 1 1 0 -0.0048 12 0 0 0 - - - - - 5.4219 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.20515.20515.2 0.00438 16-Sep K.ELALSALLK[136.11].F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 964.6048 1.07 61767 20515 2 964.604622 483.3097 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3777.9 - 684290 - - - -0.2187 - 1.899 0.333 - 271.2 1 2 0 -0.0002 9 0 0 0 2.80E+07 2.63E+07 - - - 3.3559 0.9042 230117_WJC_METTL3_WT_vs_EV_F07.20516.20516.2 0.00395 20-Aug K.C[160.03]GPMVLDALIK[136.11].L "sp|P21912|SDHB_HUMAN,tr|A0A087WWT1|A0A087WWT1_HUMAN,tr|A0A087WXX8|A0A087WXX8_HUMAN" 3 1223.6498 -1 61768 20516 2 1223.637733 612.8322 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.83 3778.1 - 591506 - - - -9.8214 - 1.603 0.376 - 125.1 1 2 0 -0.012 11 0 0 0 0.00E+00 0.00E+00 - - - 3.0909 1 230117_WJC_METTL3_WT_vs_EV_F07.20518.20518.2 0.000437 14/22 K.VESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1404.75 1.78 61770 20518 2 1404.748317 703.3823 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3778.3 - 477860 - - - -1.2315 - 2.788 0.464 - 683.2 1 2 0 -0.0017 12 0 0 0 1.13E+07 6.35E+06 - - - 5.1654 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20521.20521.2 0.00214 14-Sep K.QELLELFK.E "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1018.5699 1.05 61773 20521 2 1018.572363 510.2922 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 4.53 3778.7 - 441608 - - - 2.4201 - 1.844 0.323 - 299 1 2 0 0.0025 8 0 0 0 1.55E+07 1.48E+07 - - - 3.2715 1 230117_WJC_METTL3_WT_vs_EV_F07.20522.20522.2 2.53E-06 26-Dec R.IGPYQPNVPVGIDY.V "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1530.7718 - 61774 20522 2 1530.771472 766.3932 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 3.8 3778.9 - 441409 - - - -0.2437 - 2.057 0.517 - 376.3 1 1 0 -0.0004 14 0 0 0 - - - - - 4.6694 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.20523.20523.2 7.41E-08 24-Nov R.VFFVYVGGESPLK.E "sp|Q96JJ7|TMX3_HUMAN,tr|B4DIE3|B4DIE3_HUMAN" 2 1440.7653 1.37 61775 20523 2 1440.764194 721.3899 Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2 5.97 3779 - 383595 - - - -0.7697 - 2.338 0.392 - 439.4 1 2 0 -0.0011 13 0 0 0 1.60E+06 1.17E+06 - - - 4.1157 1 230117_WJC_METTL3_WT_vs_EV_F07.20532.20532.2 0.00264 13/20 K.IGPITPLEFYR.E "sp|Q13867|BLMH_HUMAN,tr|K7ESE8|K7ESE8_HUMAN,tr|J3KSD8|J3KSD8_HUMAN,tr|K7ES02|K7ES02_HUMAN" 4 1304.7129 9.47 61783 20532 2 1304.713628 653.3637 Bleomycin hydrolase OS=Homo sapiens OX=9606 GN=BLMH PE=1 SV=1 6 3779.9 - 1.21E+06 - - - 0.5787 - 2.339 0.492 - 548.7 1 2 0 0.0008 11 0 0 0 5.28E+07 5.57E+06 - - - 4.9734 0.9938 230117_WJC_METTL3_WT_vs_EV_F07.20533.20533.2 0.229 14-Aug R.KIPVPANR[166.11].Y "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 903.553 - 61784 20533 2 903.554222 452.7838 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 11 3779.9 - 1.15E+06 - - - 1.4011 - 1.642 0.038 - 218.2 1 2 0 0.0013 8 0 0 0 - - - - - 0.8169 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.20534.20534.2 0.0188 16-Aug K.ELALSALLK.F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 956.5906 1.07 61785 20534 2 956.589802 479.3026 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3780 - 1.02E+06 - - - -0.8687 - 1.596 0.236 - 210.1 1 2 0 -0.0008 9 0 0 0 2.79E+07 2.62E+07 - - - 2.1363 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.20535.20535.2 0.0378 14-Aug K.QELLELFK[136.11].E "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1026.5841 1.05 61786 20535 2 1026.584246 514.2993 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 4.53 3780.1 - 977973 - - - 0.1442 - 1.485 0.261 - 233 1 2 0 0.0001 8 0 0 0 1.55E+07 1.48E+07 - - - 2.1613 0.9882 230117_WJC_METTL3_WT_vs_EV_F07.20536.20536.2 4.07 14-Jul R.SGLLGELR.N "sp|O60336|MABP1_HUMAN,tr|D6RHX7|D6RHX7_HUMAN" 2 843.4814 10.92 61787 20536 2 843.481255 422.748 Mitogen-activated protein kinase-binding protein 1 OS=Homo sapiens OX=9606 GN=MAPKBP1 PE=1 SV=4 5.72 3780.2 - 752199 - - - -0.1921 - 1.402 0.087 - 155.9 1 2 0 -0.0002 8 0 0 0 1.81E+07 1.66E+06 - - - 0.7026 1 230117_WJC_METTL3_WT_vs_EV_F07.20541.20541.2 6.10E-07 22-Dec R.LLTFMGMAVENK[136.11].E "sp|Q7L2H7|EIF3M_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 2 1360.6974 0.88 61792 20541 2 1360.699695 681.356 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6 3780.7 - 415592 - - - 1.6646 - 2.499 0.583 - 498.1 1 2 0 0.0023 12 0 0 0 5.52E+06 6.25E+06 - - - 5.7562 0.999 230117_WJC_METTL3_WT_vs_EV_F07.20543.20543.2 0.00889 16-Aug K.LLYTFPGWK[136.11].V "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1131.6208 1.47 61794 20543 2 1131.622603 566.8177 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 8.59 3780.9 - 227514 - - - 1.5783 - 1.663 0.26 - 135.2 1 2 0 0.0018 9 0 0 0 2.00E+07 1.36E+07 - - - 2.4323 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.20547.20547.2 0.00195 16-Jul K.LISLFQAMK.K "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1049.5943 5.47 61797 20547 2 1049.594217 525.8044 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.75 3781.4 - 1.44E+06 - - - -0.1153 - 1.575 0.377 - 100.3 1 2 0 -0.0001 9 0 0 0 4.13E+06 7.54E+05 - - - 3.1397 1 230117_WJC_METTL3_WT_vs_EV_F07.20549.20549.2 4.37E-05 22-Sep K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.8 61799 20549 2 1317.709506 659.862 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3781.4 - 5.10E+06 - - - 0.0994 - 2.194 0.563 - 141.1 1 2 0 0.0001 12 0 0 0 3.29E+08 4.11E+08 - - - 5.2667 1 230117_WJC_METTL3_WT_vs_EV_F07.20551.20551.2 0.000405 20-Nov R.IISLETYNLLR.E "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1333.7606 2.26 61801 20551 2 1333.759927 667.8876 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 3781.5 - 2.64E+06 - - - -0.4686 - 2.167 0.48 - 422.6 1 2 0 -0.0006 11 0 0 0 1.58E+07 6.97E+06 - - - 4.6782 1 230117_WJC_METTL3_WT_vs_EV_F07.20552.20552.2 5.95E-06 18-Oct -.MFLYNLTLQR.A "sp|Q15393|SF3B3_HUMAN,tr|H3BMB0|H3BMB0_HUMAN,tr|I3L4G7|I3L4G7_HUMAN" 3 1297.6853 0.08 61802 20552 2 1297.684198 649.8499 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.5 3781.6 - 1.77E+06 - - - -0.8323 - 2.183 0.519 - 379 1 2 0 -0.0011 10 0 0 0 2.07E+07 2.45E+08 - - - 5.0532 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.20553.20553.2 6.03E-05 18-Oct K.AEVLWLMGAK.S sp|O94906|PRP6_HUMAN 1 1116.6002 0.66 61803 20553 2 1116.598847 559.3074 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.05 3781.6 - 1.73E+06 - - - -1.1687 - 2.084 0.451 - 434.9 1 2 0 -0.0013 10 0 0 0 1.20E+07 1.80E+07 - - - 4.4213 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20557.20557.2 0.000133 16-Sep K.DLFQVAFNR.V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN" 15 1108.5665 1.78 61807 20557 2 1108.568245 555.2905 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.84 3782 - 889726 - - - 1.5353 - 1.707 0.48 - 270.3 1 2 0 0.0017 9 0 0 0 4.13E+06 2.32E+06 - - - 4.1328 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20562.20562.2 9.88E-05 24-Sep K.LFQEDDEIPLYLK.G "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6RGV5|D6RGV5_HUMAN" 4 1621.8239 1.05 61810 20562 2 1621.825055 811.9192 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 3.92 3782.5 - 3.33E+06 - - - 0.6875 - 1.93 0.479 - 191 1 2 0 0.0011 13 0 0 0 2.25E+07 2.14E+07 - - - 4.2661 1 230117_WJC_METTL3_WT_vs_EV_F07.20564.20564.2 1.59E-08 24-Dec K.LFQEDDEIPLYLK[136.11].G "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6RGV5|D6RGV5_HUMAN" 4 1629.8381 1.05 61811 20564 2 1629.836256 815.9263 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 3.92 3782.6 - 2.51E+06 - - - -1.1559 - 2.439 0.626 - 372.4 1 2 0 -0.0019 13 0 0 0 2.25E+07 2.14E+07 - - - 5.9523 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20565.20565.2 0.000443 14-Jul R.EIFNFVLK[136.11].A sp|P78527|PRKDC_HUMAN 1 1016.5786 1.01 61812 20565 2 1016.579295 509.2966 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6.1 3782.6 - 2.15E+06 - - - 0.666 - 1.444 0.411 - 188.9 1 2 0 0.0007 8 0 0 0 1.89E+07 1.87E+07 - - - 3.1845 1 230117_WJC_METTL3_WT_vs_EV_F07.20567.20567.2 6.84E-11 21/30 K.IITLEEGDIILTGTPK.G sp|Q6P587|FAHD1_HUMAN 1 1711.9608 1.99 61814 20567 2 1711.957885 856.9877 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3782.9 - 1.62E+06 - - - -1.684 - 3.649 0.666 - 1391.9 1 2 0 -0.0029 16 0 0 0 1.37E+07 6.90E+06 - - - 7.1416 1 230117_WJC_METTL3_WT_vs_EV_F07.20569.20569.2 1.45E-08 14/30 R.LMNDMTAVALNYGIYK.Q sp|Q92598|HS105_HUMAN 1 1815.8899 110.32 61816 20569 2 1815.891735 908.9522 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.83 3783.2 - 1.18E+06 - - - 0.9951 - 3.058 0.631 - 451.9 1 2 0 0.0018 16 0 0 0 8.75E+06 7.93E+04 - - - 6.4491 0.9952 230117_WJC_METTL3_WT_vs_EV_F07.20571.20571.2 0.0421 18-Aug K.ITIAAYLPLK[136.11].A sp|Q8TEM1|PO210_HUMAN 1 1109.694 2.78 61818 20571 2 1109.692448 555.8543 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 8.59 3783.4 - 323177 - - - -1.3824 - 1.374 0.287 - 113.8 1 2 0 -0.0015 10 0 0 0 7.31E+06 2.63E+06 - - - 2.0472 1 230117_WJC_METTL3_WT_vs_EV_F07.20572.20572.2 0.000356 13/24 K.LILLITQVTASEK[136.11].T sp|Q15061|WDR43_HUMAN 1 1435.8741 0.97 61819 20572 2 1435.872032 718.9443 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3783.5 - 240930 - - - -1.4625 - 2.796 0.448 - 536.3 1 2 0 -0.0021 13 0 0 0 2.81E+06 2.90E+06 - - - 4.9881 0.9998 230117_WJC_METTL3_WT_vs_EV_F07.20573.20573.3 5.95E-06 Dec-44 K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.78 61820 20573 3 1317.709058 440.2437 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3783.5 - 0 - - - -0.2406 - 2.017 0.443 - 270.4 1 2 0 -0.0003 12 0 0 0 1.56E+07 1.99E+07 - - - 5.4237 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20576.20576.2 0.0104 16-Nov K.EIIDLVLDR.L "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 9 1084.6128 3.3 61822 20576 2 1084.612248 543.3137 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.03 3783.9 - 3.06E+07 - - - -0.532 - 2.209 0.393 - 522.2 1 2 0 -0.0006 9 0 0 0 4.62E+08 1.40E+08 - - - 4.2364 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20577.20577.2 0.000515 16-Nov K.EIIDLVLDR[166.11].L "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 9 1094.6211 3.3 61823 20577 2 1094.623292 548.3178 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.03 3783.9 - 9.53E+06 - - - 2.0071 - 2.225 0.39 - 513.3 1 2 0 0.0022 9 0 0 0 4.62E+08 1.40E+08 - - - 4.2346 0.9679 230117_WJC_METTL3_WT_vs_EV_F07.20583.20583.2 0.000189 16-Sep R.YEGFFGLYR[166.11].G "sp|O75746|CMC1_HUMAN,sp|Q9UJS0|CMC2_HUMAN" 2 1160.553 1.37 61829 20583 2 1160.548409 581.2838 Calcium-binding mitochondrial carrier protein Aralar1 OS=Homo sapiens OX=9606 GN=SLC25A12 PE=1 SV=2 6 3784.7 - 690825 - - - -3.9688 - 1.657 0.173 - 268.6 1 2 0 -0.0046 9 0 0 0 5.93E+06 4.33E+06 - - - 1.7783 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.20584.20584.2 1.13E-05 18-Aug K.FTMVQVWPVR.Q "sp|P38606|VATA_HUMAN,tr|C9JA17|C9JA17_HUMAN,tr|C9JVW8|C9JVW8_HUMAN" 3 1261.6641 1.87 61830 20584 2 1261.662356 631.8394 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 9.75 3784.8 - 560743 - - - -1.4211 - 1.789 0.519 - 281.2 1 2 0 -0.0018 10 0 0 0 9.11E+06 4.86E+06 - - - 4.4974 1 230117_WJC_METTL3_WT_vs_EV_F07.20588.20588.2 2.81E-07 26-Nov R.WSSMEIMEAYSVAR.Q "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|Q5TG81|Q5TG81_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 5 1658.7433 0.82 61834 20588 2 1658.744379 830.3789 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 4.53 3785.4 - 348398 - - - 0.6722 - 2.385 0.626 - 389 1 2 0 0.0011 14 0 0 0 3.14E+06 3.81E+06 - - - 5.8455 0.9262 230117_WJC_METTL3_WT_vs_EV_F07.20595.20595.2 0.000811 22-Dec R.VALDMTTLTIMR[166.11].Y "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 4 1373.7286 1.01 61841 20595 2 1374.736896 687.8716 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.81 3786.3 - 182990 - - - 733.9754 - 2.434 0.385 - 464.7 1 2 0 1.0083 12 0 0 0 1.31E+07 1.31E+07 - - - 3.9085 0.8753 230117_WJC_METTL3_WT_vs_EV_F07.20597.20597.2 0.000505 16-Jul K.LLYTFPGWK.V "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1123.6066 1.47 61842 20597 2 1124.611962 562.8106 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 8.59 3786.5 - 3.15E+06 - - - 894.7482 - 1.587 0.26 - 127.6 1 2 0 1.0053 9 0 0 0 2.00E+07 1.36E+07 - - - 1.9818 0.9951 230117_WJC_METTL3_WT_vs_EV_F07.20598.20598.2 0.147 14-Jul R.EVMLILIR.E sp|O75533|SF3B1_HUMAN 1 985.5994 0.38 61843 20598 2 985.598577 493.807 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.1 3786.6 - 529878 - - - -0.8594 - 1.359 0.238 - 181.7 1 2 0 -0.0008 8 0 0 0 2.60E+06 6.76E+06 - - - 1.7237 1 230117_WJC_METTL3_WT_vs_EV_F07.20599.20599.2 1.02E-06 13/28 K.GVYPDLLATSGDYLR.V sp|P61962|DCAF7_HUMAN 1 1638.8253 1.68 61844 20599 2 1638.824569 820.4199 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3786.6 - 4.39E+06 - - - -0.4686 - 2.403 0.59 - 443.4 1 2 0 -0.0008 15 0 0 0 1.87E+07 1.11E+07 - - - 5.554 1 230117_WJC_METTL3_WT_vs_EV_F07.20603.20603.2 2.14E-07 14/26 R.YSALFLGVAYGATR[166.11].Y sp|P56385|ATP5I_HUMAN 1 1497.7855 1.62 61848 20603 2 1497.780725 749.9 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3786.9 - 1.61E+06 - - - -3.2114 - 2.801 0.668 - 618.9 1 2 0 -0.0048 14 0 0 0 3.87E+07 2.39E+07 - - - 6.558 0.9313 230117_WJC_METTL3_WT_vs_EV_F07.20605.20605.2 2.89 22-Apr R.VALDMTTLTIMR.Y "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 4 1363.7203 1.01 61850 20605 2 1363.720148 682.8674 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.81 3787 - 1.44E+06 - - - -0.143 - 0.938 0.134 - 46.2 7 2 0 -0.0002 12 0 0 0 1.31E+07 1.31E+07 - - - -0.5153 1 230117_WJC_METTL3_WT_vs_EV_F07.20613.20613.3 1.40E-08 17/44 K.TVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1309.6952 0.78 61856 20613 3 1309.692386 437.5723 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3787.9 - 4.90E+06 - - - -2.1295 - 2.911 0.61 - 558.2 1 2 0 -0.0028 12 0 0 0 1.56E+07 1.99E+07 - - - 8.3018 1 230117_WJC_METTL3_WT_vs_EV_F07.20614.20614.2 3.34E-08 16/26 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.62 61857 20614 2 1487.7713 744.8959 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3788 - 2.51E+06 - - - -4.0093 - 2.857 0.505 - 755.9 1 2 0 -0.006 14 0 0 0 3.87E+07 2.39E+07 - - - 5.4034 0.9914 230117_WJC_METTL3_WT_vs_EV_F07.20615.20615.2 0.123 14-Jun R.LLDFLNVK[136.11].N sp|Q8NDZ4|DIK2A_HUMAN 1 968.5786 0.77 61858 20615 2 968.576963 485.2966 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 5.84 3788 - 4.28E+06 - - - -1.7087 - 1.112 0.318 - 76.8 1 2 0 -0.0017 8 0 0 0 1.11E+07 1.43E+07 - - - 1.7094 1 230117_WJC_METTL3_WT_vs_EV_F07.20620.20620.2 1.63E-09 15/28 K.GVYPDLLATSGDYLR[166.11].V sp|P61962|DCAF7_HUMAN 1 1648.8336 1.68 61863 20620 2 1648.830307 825.4241 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3788.5 - 1.65E+06 - - - -2.0014 - 2.573 0.601 - 441.1 1 2 0 -0.0033 15 0 0 0 1.87E+07 1.11E+07 - - - 5.8025 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20623.20623.2 0.0924 14-Oct R.VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 891.6145 1.34 61866 20623 2 891.614748 446.8145 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3788.8 - 1.28E+06 - - - 0.286 - 1.958 0.328 - 337.3 1 2 0 0.0003 8 0 0 0 3.43E+07 2.56E+07 - - - 3.49 0.999 230117_WJC_METTL3_WT_vs_EV_F07.20625.20625.2 0.00784 18-Sep K.LVFPQDLLEK[136.11].G "sp|Q8TCT9|HM13_HUMAN,tr|A0A3B3IT72|A0A3B3IT72_HUMAN,tr|A0A0S2Z6F0|A0A0S2Z6F0_HUMAN,tr|A0A3B3IUB5|A0A3B3IUB5_HUMAN,tr|A0A075B6F6|A0A075B6F6_HUMAN" 5 1208.6896 1.36 61868 20625 2 1208.69148 605.3521 Minor histocompatibility antigen H13 OS=Homo sapiens OX=9606 GN=HM13 PE=1 SV=1 4.37 3789.1 - 805907 - - - 1.5347 - 1.705 0.252 - 245.7 1 2 0 0.0019 10 0 0 0 9.62E+06 7.07E+06 - - - 2.391 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.20633.20633.2 0.0544 18-Nov K.VGDPVYLLGQ.- "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN" 2 1059.5601 - 61874 20633 2 1059.559065 530.7873 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 3.8 3790.1 - 1.42E+06 - - - -0.94 - 1.948 0.345 - 444.2 1 2 0 -0.001 10 0 0 0 - - - - - 3.4501 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.20635.20635.2 0.00149 14-Sep K.AWGILTFK[136.11].G "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 942.5418 1.07 61876 20635 2 942.538338 472.2782 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 8.8 3790.4 - 912643 - - - -3.7144 - 1.85 0.429 - 319.8 1 2 0 -0.0035 8 0 0 0 5.52E+07 5.15E+07 - - - 4.0639 0.9736 230117_WJC_METTL3_WT_vs_EV_F07.20636.20636.2 0.0398 14-Aug K.AWGILTFK.G "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 934.5276 1.05 61877 20636 2 934.52352 468.2711 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 8.8 3790.5 - 886354 - - - -4.4076 - 1.516 0.262 - 196.9 1 2 0 -0.0041 8 0 0 0 4.91E+07 4.66E+07 - - - 2.2297 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.20638.20638.2 0.0347 14-Aug R.VLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 881.6062 1.34 61879 20638 2 881.605686 441.8104 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3790.8 - 629632 - - - -0.6091 - 1.737 0.377 - 169.5 1 2 0 -0.0005 8 0 0 0 3.43E+07 2.56E+07 - - - 3.4906 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.20642.20642.2 0.000178 16-Aug K.DVMDALILK[136.11].M sp|Q8N1G4|LRC47_HUMAN 1 1024.5718 1.27 61883 20642 2 1024.57071 513.2932 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 4.21 3791.3 - 404555 - - - -1.0814 - 1.577 0.448 - 153.6 1 2 0 -0.0011 9 0 0 0 7.25E+06 5.69E+06 - - - 3.6674 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20644.20644.2 0.00502 18-Oct K.VLEAELLVLR[166.11].Q sp|P07196|NFL_HUMAN 1 1163.7153 0.001 61885 20644 2 1163.714785 582.8649 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.53 3791.5 - 325472 - - - -0.4683 - 2.003 0.408 - 365.3 1 2 0 -0.0005 10 0 0 0 0.00E+00 5.52E+06 - - - 3.9933 0.9966 230117_WJC_METTL3_WT_vs_EV_F07.20655.20655.2 0.00352 16-Aug K.DVMDALILK.M sp|Q8N1G4|LRC47_HUMAN 1 1016.5576 1.26 61893 20655 2 1016.555568 509.2861 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 4.21 3792.9 - 1.05E+06 - - - -2.0166 - 1.492 0.359 - 168.6 1 2 0 -0.0021 9 0 0 0 7.12E+06 5.65E+06 - - - 2.8495 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20656.20656.2 1.22E-05 18-Aug K.LLPFLSNPYR.N sp|Q13625|ASPP2_HUMAN 1 1218.6761 2.02 61894 20656 2 1218.679049 610.3453 Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=9606 GN=TP53BP2 PE=1 SV=2 8.75 3793.1 - 629493 - - - 2.4248 - 1.597 0.449 - 243 1 2 0 0.003 10 0 0 0 5.13E+06 2.54E+06 - - - 3.6631 0.995 230117_WJC_METTL3_WT_vs_EV_F07.20663.20663.2 0.0477 16-Oct K.IQLPIIQLR.K sp|O15111|IKKA_HUMAN 1 1092.7019 5.77 61899 20663 2 1092.698434 547.3582 Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Homo sapiens OX=9606 GN=CHUK PE=1 SV=2 9.75 3794 - 493913 - - - -3.1857 - 2.099 0.29 - 311.9 1 2 0 -0.0035 9 0 0 0 4.41E+06 7.64E+05 - - - 3.3269 1 230117_WJC_METTL3_WT_vs_EV_F07.20664.20664.2 0.000118 20-Nov K.FMELLEPLNER.K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1389.6962 1.41 61900 20664 2 1389.692186 695.8554 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.25 3794.1 - 738886 - - - -2.915 - 2.203 0.492 - 538.3 1 2 0 -0.0041 11 0 0 0 4.96E+06 3.51E+06 - - - 4.8103 0.998 230117_WJC_METTL3_WT_vs_EV_F07.20665.20665.2 2.43E-05 20-Nov K.GIFNGFSVTLK[136.11].E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1189.6587 1.28 61901 20665 2 1189.664015 595.8366 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3794.3 - 652479 - - - 4.5021 - 2.078 0.348 - 286.5 1 2 0 0.0054 11 0 0 0 2.03E+07 1.59E+07 - - - 3.5883 1 230117_WJC_METTL3_WT_vs_EV_F07.20668.20668.2 9.75E-06 20-Nov K.GIFNGFSVTLK.E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1181.6445 1.31 61904 20668 2 1181.636325 591.8295 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3794.6 - 442505 - - - -6.8836 - 2.047 0.527 - 318.6 1 2 0 -0.0081 11 0 0 0 2.03E+07 1.55E+07 - - - 4.8688 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20670.20670.2 5.70E-05 Oct-34 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.17 61906 20670 2 1968.070784 985.0433 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3794.9 - 380070 - - - -0.6433 - 1.855 0.499 - 173.5 1 2 0 -0.0013 18 0 0 0 2.81E+06 2.40E+06 - - - 4.2453 0.9931 230117_WJC_METTL3_WT_vs_EV_F07.20673.20673.2 0.0039 Sep-34 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 -1 61909 20673 2 1976.079464 989.0504 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3795.3 - 163854 - - - -3.4341 - 1.64 0.385 - 162.4 1 2 0 -0.0068 18 0 0 0 0.00E+00 0.00E+00 - - - 3.0987 0.9544 230117_WJC_METTL3_WT_vs_EV_F07.20675.20675.2 0.0192 18-Dec K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 -1 61910 20675 2 1168.697981 585.3606 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3795.7 - 2.80E+06 - - - -7.4818 - 2.263 0.349 - 373.5 1 2 0 -0.0087 10 0 0 0 0.00E+00 0.00E+00 - - - 3.8956 0.9285 230117_WJC_METTL3_WT_vs_EV_F07.20680.20680.2 0.016 18-Jul R.LGFEGGQTPF.Y "sp|Q9P015|RM15_HUMAN,tr|E5RHF4|E5RHF4_HUMAN" 2 1051.4975 - 61915 20680 2 1051.497481 526.756 "39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1" 4 3796.3 - 1.44E+06 - - - 0.019 - 1.355 0.401 - 114.9 1 1 0 0 10 0 0 0 - - - - - 2.8508 0.995 230117_WJC_METTL3_WT_vs_EV_F07.20683.20683.2 0.126 16-Jun K.DLSDFPLIK.K "sp|P20585|MSH3_HUMAN,tr|A0A590UJN8|A0A590UJN8_HUMAN,tr|A0A590UKC9|A0A590UKC9_HUMAN,tr|A0A590UJW0|A0A590UJW0_HUMAN" 4 1046.5648 0.89 61918 20683 2 1046.564821 524.2897 DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4 4.21 3796.7 - 965355 - - - 0.0086 - 1.302 0.228 - 82.5 3 2 0 0 9 0 0 0 2.21E+06 2.49E+06 - - - 1.2754 0.9426 230117_WJC_METTL3_WT_vs_EV_F07.20684.20684.2 0.000299 16-Sep R.LVSYYYFLR[166.11].F sp|Q7LGA3|HS2ST_HUMAN 1 1232.6469 0.86 61919 20684 2 1232.637898 617.3307 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 8.5 3796.8 - 872294 - - - -7.316 - 1.475 0.431 - 269.4 1 2 0 -0.009 9 0 0 0 2.04E+07 2.37E+07 - - - 3.3459 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.20685.20685.2 0.0394 16-Aug R.LVFGFLNGR.A "sp|P00491|PNPH_HUMAN,tr|G3V2H3|G3V2H3_HUMAN,tr|G3V5M2|G3V5M2_HUMAN" 3 1021.5709 -1 61920 20685 2 1021.571229 511.7927 Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2 9.75 3796.9 - 681529 - - - 0.3211 - 1.223 0.351 - 208.6 1 2 0 0.0003 9 0 0 0 0.00E+00 0.00E+00 - - - 2.2158 0.9928 230117_WJC_METTL3_WT_vs_EV_F07.20694.20694.2 0.171 16-Aug R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 999 61929 20694 2 1006.574627 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3798.1 - 178715 - - - 4.6981 - 1.527 0.253 - 134.1 1 2 0 0.0047 9 0 0 0 8.60E+05 0.00E+00 - - - 2.1328 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.20696.20696.2 0.0792 18-Oct K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 2 61930 20696 2 1176.720106 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3798.3 - 0 - - - -0.696 - 2.039 0.246 - 219.4 1 2 0 -0.0008 10 0 0 0 2.04E+07 1.02E+07 - - - 2.8464 1 230117_WJC_METTL3_WT_vs_EV_F07.20698.20698.2 7.57E-06 13/22 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 4079.64 61931 20698 2 1603.764372 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3798.6 - 2.20E+08 - - - 0.2694 - 2.108 0.604 - 465.3 1 2 0 0.0004 12 0 0 0 6.77E+09 1.66E+06 - - - 5.4642 1 230117_WJC_METTL3_WT_vs_EV_F07.20700.20700.2 6.00E-09 17/24 R.GAVGALLVYDIAK.H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1288.7391 1.44 61933 20700 2 1288.736129 645.3768 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3798.8 - 639561 - - - -2.296 - 3.278 0.449 - 1709.7 1 2 0 -0.003 13 0 0 0 9.70E+07 6.75E+07 - - - 5.4035 1 230117_WJC_METTL3_WT_vs_EV_F07.20701.20701.2 8.63E-07 14/24 R.GAVGALLVYDIAK[136.11].H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1296.7533 1.44 61934 20701 2 1296.754232 649.3839 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3799 - 419155 - - - 0.728 - 3.049 0.519 - 1034.4 1 2 0 0.0009 13 0 0 0 9.70E+07 6.75E+07 - - - 5.7352 1 230117_WJC_METTL3_WT_vs_EV_F07.20704.20704.2 0.000122 26-Nov K.VTVNPGLLVPLDVK.L sp|Q6KB66|K2C80_HUMAN 1 1462.8759 999 61937 20704 2 1462.872421 732.4452 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 5.81 3799.4 - 215744 - - - -2.3891 - 2.061 0.541 - 301.7 1 2 0 -0.0035 14 0 0 0 3.01E+06 0.00E+00 - - - 4.8505 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20706.20706.2 0.0382 20-Sep K.FMELLEPLNER[166.11].K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1399.7045 1.41 61939 20706 2 1399.706001 700.8595 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.25 3799.6 - 201283 - - - 1.0674 - 1.489 0.383 - 159.1 1 2 0 0.0015 11 0 0 0 4.96E+06 3.51E+06 - - - 2.9463 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.20711.20711.2 0.00206 16-Sep K.C[160.03]MPTFQFFK.K sp|P10599|THIO_HUMAN 1 1204.5409 2.63 61942 20711 2 1204.53968 603.2777 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3800.3 - 904523 - - - -1.0319 - 1.385 0.428 - 200.9 1 2 0 -0.0012 9 0 0 0 6.05E+07 2.30E+07 - - - 3.1441 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.20713.20713.2 0.00887 16-Aug R.FTGLESIFR[166.11].A sp|Q8N4Q0|PTGR3_HUMAN 1 1078.5687 0.77 61944 20713 2 1078.567237 540.2916 Prostaglandin reductase 3 OS=Homo sapiens OX=9606 GN=ZADH2 PE=1 SV=1 6 3800.5 - 1.07E+06 - - - -1.324 - 1.517 0.408 - 168.2 1 2 0 -0.0014 9 0 0 0 6.27E+07 8.12E+07 - - - 3.2597 1 230117_WJC_METTL3_WT_vs_EV_F07.20719.20719.3 4.77E-08 18/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 2406.28 61949 20719 3 1603.763623 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3801.3 - 1.50E+07 - - - -0.1977 - 2.712 0.638 - 498.5 1 2 0 -0.0003 12 0 0 0 6.66E+08 2.77E+05 - - - 8.4184 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20722.20722.2 0.000208 18-Oct R.IYLDMLNVYK.C "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 11 1270.6631 1.52 61951 20722 2 1270.66285 636.3388 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.83 3801.7 - 714288 - - - -0.2329 - 1.929 0.448 - 301.8 1 2 0 -0.0003 10 0 0 0 2.43E+07 1.60E+07 - - - 4.1837 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.20723.20723.2 0.000249 16-Sep K.C[160.03]MPTFQFFK[136.11].K sp|P10599|THIO_HUMAN 1 1212.5551 2.63 61952 20723 2 1212.555226 607.2848 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3801.8 - 918205 - - - 0.0849 - 1.342 0.415 - 203.3 1 2 0 0.0001 9 0 0 0 6.05E+07 2.30E+07 - - - 2.9572 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.20724.20724.2 0.297 18-Sep R.IYLDMLNVYK[136.11].C "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 11 1278.6773 1.66 61953 20724 2 1278.681044 640.3459 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.83 3801.9 - 643136 - - - 2.8921 - 1.619 0.224 - 210.5 1 2 0 0.0037 10 0 0 0 2.65E+07 1.60E+07 - - - 2.0392 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20726.20726.2 0.157 18-Oct K.DLIGVQNLLK[136.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1119.6743 0.89 61955 20726 2 1119.676064 560.8444 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3802.2 - 468796 - - - 1.5665 - 1.848 0.381 - 228.4 1 2 0 0.0018 10 0 0 0 2.06E+07 2.30E+07 - - - 3.5687 1 230117_WJC_METTL3_WT_vs_EV_F07.20727.20727.2 0.000426 14/26 K.IPVTIITGYLGAGK.T "sp|Q5RIA9|CBWD5_HUMAN,sp|Q9BRT8|CBWD1_HUMAN,sp|Q5JTY5|CBWD3_HUMAN,sp|Q4V339|CBWD6_HUMAN,sp|Q8IUF1|CBWD2_HUMAN,tr|A0A087WZQ3|A0A087WZQ3_HUMAN,tr|Q5JTY2|Q5JTY2_HUMAN,tr|Q6NVZ8|Q6NVZ8_HUMAN,tr|A0A0B4J2E3|A0A0B4J2E3_HUMAN,tr|A0A087X140|A0A087X140_HUMAN,tr|F8WEU0|F8WEU0_HUMAN,tr|E7EUZ7|E7EUZ7_HUMAN,tr|F8WEG4|F8WEG4_HUMAN,tr|A0A087WYD2|A0A087WYD2_HUMAN,tr|A0A0A0MRU4|A0A0A0MRU4_HUMAN,tr|Q5RIB0|Q5RIB0_HUMAN,tr|H0Y5V3|H0Y5V3_HUMAN,tr|A0A0A6YYH9|A0A0A6YYH9_HUMAN,tr|A0A087WWG3|A0A087WWG3_HUMAN,tr|A0A087WTC0|A0A087WTC0_HUMAN,tr|C9J3G2|C9J3G2_HUMAN,tr|F2Z2T4|F2Z2T4_HUMAN,tr|Q5RIB5|Q5RIB5_HUMAN" 23 1401.8232 7.73 61956 20727 2 1401.822344 701.9189 COBW domain-containing protein 5 OS=Homo sapiens OX=9606 GN=CBWD5 PE=2 SV=1 8.59 3802.3 - 443495 - - - -0.5764 - 2.784 0.453 - 590.1 1 2 0 -0.0008 14 0 0 0 4.73E+06 6.12E+05 - - - 4.956 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.20730.20730.2 0.0201 18-Oct K.DLIGVQNLLK.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1111.6601 0.87 61959 20730 2 1111.663881 556.8373 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3802.7 - 354968 - - - 3.3922 - 1.819 0.349 - 212.6 1 2 0 0.0038 10 0 0 0 1.99E+07 2.30E+07 - - - 3.2875 0.9962 230117_WJC_METTL3_WT_vs_EV_F07.20731.20731.2 0.00162 18-Aug K.DSPFGLSFVR.F "sp|P18887|XRCC1_HUMAN,tr|M0R1U8|M0R1U8_HUMAN,tr|M0R0D2|M0R0D2_HUMAN,tr|M0QYS5|M0QYS5_HUMAN,tr|F5H8D7|F5H8D7_HUMAN,tr|M0QZ96|M0QZ96_HUMAN" 6 1123.5662 1.79 61960 20731 2 1123.564188 562.7904 DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2 5.84 3802.8 - 350853 - - - -1.7987 - 1.449 0.337 - 193.3 1 2 0 -0.002 10 0 0 0 5.53E+06 3.09E+06 - - - 2.5647 1 230117_WJC_METTL3_WT_vs_EV_F07.20732.20732.2 3.22E-07 Nov-32 K.FLSESVLAVAGDEEVIR.F sp|Q9NWT1|PK1IP_HUMAN 1 1832.952 1.44 61961 20732 2 1832.954323 917.4833 p21-activated protein kinase-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAK1IP1 PE=1 SV=2 4 3803 - 341766 - - - 1.2706 - 2.508 0.544 - 385.2 1 2 0 0.0023 17 0 0 0 2.14E+06 1.49E+06 - - - 5.3189 1 230117_WJC_METTL3_WT_vs_EV_F07.20733.20733.2 1.45E-08 14/32 K.FLSESVLAVAGDEEVIR[166.11].F sp|Q9NWT1|PK1IP_HUMAN 1 1842.9603 1.44 61962 20733 2 1842.955138 922.4874 p21-activated protein kinase-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAK1IP1 PE=1 SV=2 4 3803.1 - 283284 - - - -2.7814 - 2.93 0.605 - 378.6 1 2 0 -0.0051 17 0 0 0 2.14E+06 1.49E+06 - - - 6.1509 0.9132 230117_WJC_METTL3_WT_vs_EV_F07.20735.20735.2 0.00308 14-Aug R.PFSVDFFR.K "sp|Q9NYH9|UTP6_HUMAN,tr|J3QSA7|J3QSA7_HUMAN,tr|J3KRR8|J3KRR8_HUMAN" 3 1013.4971 1.51 61964 20735 2 1013.496117 507.7558 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 6.27 3803.4 - 239910 - - - -0.9373 - 1.495 0.419 - 224.1 1 1 0 -0.0009 8 0 0 0 3.53E+06 2.33E+06 - - - 3.3482 0.991 230117_WJC_METTL3_WT_vs_EV_F07.20737.20737.2 0.0112 16-Aug R.FVC[160.03]PVILFK[136.11].G "sp|Q8NCE2|MTMRE_HUMAN,tr|B4DJ23|B4DJ23_HUMAN" 2 1129.6449 0.51 61966 20737 2 1129.641478 565.8297 Myotubularin-related protein 14 OS=Homo sapiens OX=9606 GN=MTMR14 PE=1 SV=2 8.22 3803.6 - 194854 - - - -3.0505 - 1.478 0.313 - 162.1 1 2 0 -0.0034 9 0 0 0 4.85E+06 9.58E+06 - - - 2.482 0.9149 230117_WJC_METTL3_WT_vs_EV_F07.20743.20743.2 1.23 16-Mar R.LVSYYYFLR.F sp|Q7LGA3|HS2ST_HUMAN 1 1222.6386 0.86 61970 20743 2 1222.638144 612.3266 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 8.5 3804.2 - 627718 - - - -0.4106 - 0.797 0.161 - 31.5 2 2 0 -0.0005 9 0 0 0 2.04E+07 2.37E+07 - - - -0.5609 1 230117_WJC_METTL3_WT_vs_EV_F07.20748.20748.2 0.000204 15/24 K.ILESSQTLLSVLK.R "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1429.8392 3.35 61973 20748 2 1429.834519 715.9269 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 6 3804.7 - 6.25E+06 - - - -3.271 - 2.777 0.578 - 569.2 1 2 0 -0.0047 13 0 0 0 2.88E+07 8.59E+06 - - - 5.93 0.8813 230117_WJC_METTL3_WT_vs_EV_F07.20753.20753.2 0.00113 12-Jul Q.WIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1021.4474 1.59 61978 20753 2 1021.445825 511.731 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3805.2 - 1.51E+06 - - - -1.4998 - 1.448 0.427 - 283 1 1 0 -0.0015 7 0 0 0 2.65E+06 1.67E+06 - - - 3.3673 1 230117_WJC_METTL3_WT_vs_EV_F07.20754.20754.2 1.00E-06 20-Oct K.YFFFDDGNGLK.G sp|P61009|SPCS3_HUMAN 1 1321.5979 1.38 61979 20754 2 1321.595411 661.8062 Signal peptidase complex subunit 3 OS=Homo sapiens OX=9606 GN=SPCS3 PE=1 SV=1 4.21 3805.3 - 1.46E+06 - - - -1.8856 - 1.868 0.613 - 269 1 2 0 -0.0025 11 0 0 0 7.05E+06 5.12E+06 - - - 5.2583 1 230117_WJC_METTL3_WT_vs_EV_F07.20759.20759.2 2.19E-06 16/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 61983 20759 2 1343.610362 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3805.9 - 476734 - - - -0.8187 - 2.899 0.546 - 1019.2 1 1 0 -0.0011 10 0 0 0 3.60E+07 0.00E+00 - - - 6.0444 1 230117_WJC_METTL3_WT_vs_EV_F07.20768.20768.2 5.53E-06 17/28 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.4 61990 20768 2 1548.923385 775.4692 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3806.9 - 957604 - - - -0.3512 - 3.213 0.615 - 690.3 1 2 0 -0.0005 15 0 0 0 1.64E+08 1.17E+08 - - - 6.4528 1 230117_WJC_METTL3_WT_vs_EV_F07.20770.20770.2 6.59E-10 17/28 K.LLGASELPIVTPALR[166.11].A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1558.9322 1.4 61992 20770 2 1558.933825 780.4734 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3807.1 - 751132 - - - 1.043 - 3.361 0.517 - 630.1 1 2 0 0.0016 15 0 0 0 1.64E+08 1.17E+08 - - - 5.8394 1 230117_WJC_METTL3_WT_vs_EV_F07.20771.20771.2 6.41E-12 18/30 R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 12.06 61993 20771 2 1756.906355 879.4608 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3807.3 - 660626 - - - -0.3432 - 3.633 0.586 - 1195.9 1 2 0 -0.0006 16 0 0 0 2.28E+07 1.89E+06 - - - 6.5407 1 230117_WJC_METTL3_WT_vs_EV_F07.20773.20773.2 7.64E-09 24-Dec K.MLVLDEADEMLNK[136.11].G "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1527.7404 0.001 61995 20773 2 1527.739742 764.8775 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 3.92 3807.5 - 570315 - - - -0.4418 - 2.55 0.463 - 408.6 1 2 0 -0.0007 13 0 0 0 0.00E+00 5.55E+06 - - - 4.863 0.997 230117_WJC_METTL3_WT_vs_EV_F07.20774.20774.2 0.227 14-Jul K.DFLPIEIR.G sp|Q5VT06|CE350_HUMAN 1 1001.5546 2.7 61996 20774 2 1001.556482 501.7846 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.37 3807.7 - 503163 - - - 1.8971 - 1.556 0.144 - 195.6 1 2 0 0.0019 8 0 0 0 7.83E+06 2.90E+06 - - - 1.4374 0.9425 230117_WJC_METTL3_WT_vs_EV_F07.20775.20775.3 2.66E-05 Nov-36 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 61997 20775 3 1343.609189 448.8778 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3807.8 - 346659 - - - -1.6917 - 2.04 0.538 - 251.8 1 1 0 -0.0023 10 0 0 0 1.83E+06 0.00E+00 - - - 6.6197 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20777.20777.2 0.00672 14-Aug R.ETILNLLR[166.11].K "sp|Q6P158|DHX57_HUMAN,tr|A0A087WZ11|A0A087WZ11_HUMAN" 2 980.5894 0.88 61999 20777 2 980.589489 491.302 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 6.1 3808.1 - 150416 - - - 0.0897 - 1.897 0.356 - 214.4 1 2 0 0.0001 8 0 0 0 5.26E+06 5.94E+06 - - - 3.6014 0.998 230117_WJC_METTL3_WT_vs_EV_F07.20780.20780.2 0.0685 12-Sep R.EIALWFR[166.11].A "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 943.5155 0.84 62001 20780 2 943.513462 472.765 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6.1 3808.4 - 1.70E+06 - - - -2.1685 - 1.883 0.374 - 345.8 1 2 0 -0.002 7 0 0 0 5.31E+06 6.30E+06 - - - 3.808 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.20781.20781.2 8.13E-05 22-Dec K.IGLIQFC[160.03]LSAPK.T sp|P50991|TCPD_HUMAN 1 1345.7428 10.33 62002 20781 2 1345.738593 673.8787 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3808.5 - 1.15E+07 - - - -3.1217 - 2.264 0.427 - 398.2 1 2 0 -0.0042 12 0 0 0 6.09E+07 5.89E+06 - - - 4.3435 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20782.20782.3 7.13E-07 17/60 R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 11.44 62003 20782 3 1756.902647 586.6429 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3808.6 - 6.74E+06 - - - -2.4537 - 2.882 0.472 - 441.8 1 2 0 -0.0043 16 0 0 0 1.57E+07 1.37E+06 - - - 6.5171 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.20783.20783.2 0.000902 18-Oct K.IMLPWDPTGK.L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1156.5951 1.66 62004 20783 2 1156.591632 579.3048 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3808.6 - 4.26E+06 - - - -2.9691 - 1.701 0.492 - 382.4 1 2 0 -0.0034 10 0 0 0 5.85E+07 3.52E+07 - - - 4.1566 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.20784.20784.2 7.64E-05 18-Dec K.IMLPWDPTGK[136.11].L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1164.6093 1.66 62005 20784 2 1164.60587 583.3119 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3808.7 - 2.67E+06 - - - -2.916 - 2.003 0.443 - 528.6 1 2 0 -0.0034 10 0 0 0 5.85E+07 3.52E+07 - - - 4.2509 1 230117_WJC_METTL3_WT_vs_EV_F07.20785.20785.2 9.46E-05 18-Sep R.AFDLFNPNFK.S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1211.5975 1.43 62006 20785 2 1211.593183 606.806 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3808.8 - 2.56E+06 - - - -3.5705 - 1.933 0.506 - 247.5 1 2 0 -0.0043 10 0 0 0 1.91E+07 1.34E+07 - - - 4.6166 1 230117_WJC_METTL3_WT_vs_EV_F07.20786.20786.2 5.06E-06 18-Oct R.AFDLFNPNFK[136.11].S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1219.6117 1.43 62007 20786 2 1219.605874 610.8131 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3808.9 - 1.95E+06 - - - -4.7843 - 1.921 0.533 - 289.3 1 2 0 -0.0058 10 0 0 0 1.91E+07 1.34E+07 - - - 4.7982 0.9722 230117_WJC_METTL3_WT_vs_EV_F07.20787.20787.2 0.402 18-Oct K.QLLLIAGLTR.E "sp|Q9UJX2|CDC23_HUMAN,tr|D6RCF8|D6RCF8_HUMAN,tr|D6RBY8|D6RBY8_HUMAN,tr|H0Y936|H0Y936_HUMAN" 4 1096.6968 1.01 62008 20787 2 1096.693416 549.3557 Cell division cycle protein 23 homolog OS=Homo sapiens OX=9606 GN=CDC23 PE=1 SV=3 9.75 3809.1 - 1.65E+06 - - - -3.1121 - 1.988 0.066 - 242.4 1 2 0 -0.0034 10 0 0 0 6.04E+06 5.99E+06 - - - 1.4454 1 230117_WJC_METTL3_WT_vs_EV_F07.20788.20788.2 0.00322 22-Dec K.IGLIQFC[160.03]LSAPK[136.11].T sp|P50991|TCPD_HUMAN 1 1353.757 10.32 62009 20788 2 1353.756391 677.8858 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3809.2 - 1.32E+06 - - - -0.4454 - 2.643 0.469 - 583.1 1 2 0 -0.0006 12 0 0 0 6.08E+07 5.89E+06 - - - 5.0621 0.9952 230117_WJC_METTL3_WT_vs_EV_F07.20789.20789.2 0.00232 22-Sep K.EALQLMATYLPK.D "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 13 1376.7374 2.36 62010 20789 2 1376.73263 689.376 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 6.1 3809.3 - 1.29E+06 - - - -3.4458 - 1.816 0.411 - 197.6 1 2 0 -0.0047 12 0 0 0 7.28E+06 3.09E+06 - - - 3.645 0.9503 230117_WJC_METTL3_WT_vs_EV_F07.20790.20790.2 6.87E-05 14/22 R.LAGATLLIFANK.Q sp|P36404|ARL2_HUMAN 1 1230.7336 -1 62011 20790 2 1230.723845 616.3741 ADP-ribosylation factor-like protein 2 OS=Homo sapiens OX=9606 GN=ARL2 PE=1 SV=4 8.75 3809.4 - 1.06E+06 - - - -7.9335 - 2.1 0.421 - 445.9 1 2 0 -0.0098 12 0 0 0 0.00E+00 0.00E+00 - - - 4.0996 0.9948 230117_WJC_METTL3_WT_vs_EV_F07.20791.20791.2 0.000553 22-Aug K.LVGQSIIAYLQK.K "sp|P53621|COPA_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 3 1331.7813 -1 62012 20791 2 1331.777562 666.8979 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 8.59 3809.6 - 688923 - - - -2.797 - 1.785 0.351 - 122 3 2 0 -0.0037 12 0 0 0 0.00E+00 0.00E+00 - - - 2.9437 0.9682 230117_WJC_METTL3_WT_vs_EV_F07.20792.20792.2 5.42E-05 20-Sep R.LLEIDPYLKPY.A sp|Q04446|GLGB_HUMAN 1 1362.7435 3.57 62013 20792 2 1362.744583 682.379 "1,4-alpha-glucan-branching enzyme OS=Homo sapiens OX=9606 GN=GBE1 PE=1 SV=3" 4.37 3809.7 - 634542 - - - 0.7911 - 1.766 0.412 - 233.2 1 1 0 0.0011 11 0 0 0 2.48E+06 6.93E+05 - - - 3.6222 1 230117_WJC_METTL3_WT_vs_EV_F07.20793.20793.2 8.52E-08 20-Dec K.WYLENVYPELR[166.11].V sp|Q10471|GALT2_HUMAN 1 1490.7433 1.07 62014 20793 2 1490.739497 746.3789 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3809.9 - 560732 - - - -2.5746 - 2.427 0.438 - 630 1 2 0 -0.0038 11 0 0 0 3.06E+07 2.86E+07 - - - 4.6735 1 230117_WJC_METTL3_WT_vs_EV_F07.20795.20795.2 5.35E-09 13/28 K.LLPLGATDTAVFDVR.L "sp|Q96EY5|MB12A_HUMAN,tr|E9PLL0|E9PLL0_HUMAN,tr|E9PQA6|E9PQA6_HUMAN" 3 1586.8668 -1 62016 20795 2 1586.863573 794.4407 Multivesicular body subunit 12A OS=Homo sapiens OX=9606 GN=MVB12A PE=1 SV=1 4.21 3810.1 - 350272 - - - -2.0386 - 2.434 0.592 - 475.2 1 2 0 -0.0032 15 0 0 0 0.00E+00 0.00E+00 - - - 5.5995 0.9935 230117_WJC_METTL3_WT_vs_EV_F07.20799.20799.2 0.0359 16-Oct R.NALDLLLPK.L "sp|P30566|PUR8_HUMAN,tr|A0A096LNY5|A0A096LNY5_HUMAN,tr|A0A1B0GTJ7|A0A1B0GTJ7_HUMAN,tr|A0A1B0GWJ0|A0A1B0GWJ0_HUMAN,tr|A0A1B0GWF8|A0A1B0GWF8_HUMAN,tr|A0A096LNY4|A0A096LNY4_HUMAN,tr|A0A1B0GTG9|A0A1B0GTG9_HUMAN,tr|A0A7P0T9A7|A0A7P0T9A7_HUMAN,tr|A0A096LNY6|A0A096LNY6_HUMAN,tr|A0A096LP92|A0A096LP92_HUMAN,tr|A0A7P0Z472|A0A7P0Z472_HUMAN" 11 995.6015 1.9 62019 20799 2 995.598235 498.808 Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2 5.84 3810.7 - 1.27E+06 - - - -3.3116 - 1.877 0.299 - 372 1 2 0 -0.0033 9 0 0 0 1.37E+07 7.21E+06 - - - 3.0701 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20802.20802.2 0.000575 14-Sep K.FGFYEVFK[136.11].V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1043.5208 1.06 62022 20802 2 1043.520077 522.7677 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3811.1 - 2.49E+06 - - - -0.6631 - 1.69 0.488 - 163.2 1 2 0 -0.0007 8 0 0 0 2.30E+07 2.16E+07 - - - 4.2277 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.20803.20803.2 0.0105 14-Oct K.FGFYEVFK.V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1035.5066 1.06 62023 20803 2 1035.506008 518.7606 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3811.2 - 2.25E+06 - - - -0.5418 - 1.782 0.372 - 229.7 1 2 0 -0.0006 8 0 0 0 2.30E+07 2.16E+07 - - - 3.5308 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.20804.20804.2 0.00393 18-Oct R.LGGIAYFLSR[166.11].L "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1105.616 1.5 62024 20804 2 1105.614255 553.8153 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 8.75 3811.4 - 2.24E+06 - - - -1.5331 - 1.941 0.387 - 301.2 1 2 0 -0.0017 10 0 0 0 1.39E+07 9.24E+06 - - - 3.7501 1 230117_WJC_METTL3_WT_vs_EV_F07.20806.20806.2 7.09E-09 14/20 K.WYLENVYPELR.V sp|Q10471|GALT2_HUMAN 1 1480.7351 1.07 62026 20806 2 1480.735572 741.3748 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3811.6 - 2.08E+06 - - - 0.3424 - 2.462 0.481 - 777.4 1 2 0 0.0005 11 0 0 0 3.06E+07 2.86E+07 - - - 5.0309 1 230117_WJC_METTL3_WT_vs_EV_F07.20810.20810.2 0.000233 14/22 R.VPFLVLEC[160.03]PNLK[136.11].L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1435.7989 1.16 62030 20810 2 1435.797228 718.9067 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3812.2 - 859902 - - - -1.1353 - 2.244 0.48 - 519.6 1 2 0 -0.0016 12 0 0 0 1.04E+07 8.95E+06 - - - 4.7124 0.9871 230117_WJC_METTL3_WT_vs_EV_F07.20811.20811.2 0.145 16-Sep R.NALDLLLPK[136.11].L "sp|P30566|PUR8_HUMAN,tr|A0A096LNY5|A0A096LNY5_HUMAN,tr|A0A1B0GTJ7|A0A1B0GTJ7_HUMAN,tr|A0A1B0GWJ0|A0A1B0GWJ0_HUMAN,tr|A0A1B0GWF8|A0A1B0GWF8_HUMAN,tr|A0A096LNY4|A0A096LNY4_HUMAN,tr|A0A1B0GTG9|A0A1B0GTG9_HUMAN,tr|A0A7P0T9A7|A0A7P0T9A7_HUMAN,tr|A0A096LNY6|A0A096LNY6_HUMAN,tr|A0A096LP92|A0A096LP92_HUMAN,tr|A0A7P0Z472|A0A7P0Z472_HUMAN" 11 1003.6157 1.9 62031 20811 2 1003.613803 502.8151 Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2 5.84 3812.3 - 782258 - - - -1.9221 - 1.531 0.163 - 183.1 1 2 0 -0.0019 9 0 0 0 1.37E+07 7.21E+06 - - - 1.4765 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20812.20812.2 0.000141 30-Oct R.LMNETTAVALAYGIYK[136.11].Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1764.9212 -1 62032 20812 2 1764.922733 883.4679 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3812.4 - 673847 - - - 0.8924 - 2.303 0.436 - 189.4 1 2 0 0.0016 16 0 0 0 0.00E+00 0.00E+00 - - - 4.3118 1 230117_WJC_METTL3_WT_vs_EV_F07.20822.20822.2 1.11E-05 22-Oct K.GIDPFSLDALSK[136.11].E sp|P40227|TCPZ_HUMAN 1 1269.6696 10.24 62041 20822 2 1269.670126 635.8421 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3813.5 - 2.38E+06 - - - 0.4001 - 2.218 0.551 - 280.5 1 2 0 0.0005 12 0 0 0 5.66E+08 5.53E+07 - - - 5.2065 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.20823.20823.2 0.261 18-Dec K.ILDVLEEIPK[136.11].N "sp|Q16718|NDUA5_HUMAN,tr|C9IZN5|C9IZN5_HUMAN,tr|H7BYD0|H7BYD0_HUMAN,tr|A0A087X1G1|A0A087X1G1_HUMAN,tr|F8WAS3|F8WAS3_HUMAN,tr|A0A7I2V2W4|A0A7I2V2W4_HUMAN,tr|A0A7I2V3L8|A0A7I2V3L8_HUMAN" 7 1175.6893 2.56 62042 20823 2 1175.68836 588.8519 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3 4.14 3813.6 - 1.79E+06 - - - -0.7919 - 2.266 0.276 - 357.1 1 2 0 -0.0009 10 0 0 0 8.06E+07 3.14E+07 - - - 3.3626 0.999 230117_WJC_METTL3_WT_vs_EV_F07.20824.20824.2 0.0035 16-Sep K.TEILPPFFK.H sp|O75533|SF3B1_HUMAN 1 1090.6063 1.1 62043 20824 2 1090.605259 546.3104 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.66 3813.6 - 1.73E+06 - - - -0.9389 - 1.697 0.41 - 322.8 1 2 0 -0.001 9 0 0 0 9.19E+07 8.32E+07 - - - 3.599 1 230117_WJC_METTL3_WT_vs_EV_F07.20826.20826.2 0.0282 22-Dec R.VPFLVLEC[160.03]PNLK.L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1427.7847 1.16 62045 20826 2 1427.786985 714.8996 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3813.8 - 1.02E+06 - - - 1.6298 - 2.512 0.486 - 720.2 1 2 0 0.0023 12 0 0 0 1.04E+07 8.95E+06 - - - 5.0534 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.20830.20830.2 2.93E-05 18-Oct K.FSDFLLDPYK[136.11].Y sp|Q9UIG0|BAZ1B_HUMAN 1 1251.6267 1.23 62049 20830 2 1251.631258 626.8206 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 4.21 3814.1 - 631639 - - - 3.6489 - 2.134 0.333 - 263.5 1 2 0 0.0046 10 0 0 0 1.17E+07 9.52E+06 - - - 3.6149 1 230117_WJC_METTL3_WT_vs_EV_F07.20838.20838.2 1.22E-06 22-Dec K.GIDPFSLDALSK.E sp|P40227|TCPZ_HUMAN 1 1261.6554 10.24 62056 20838 2 1261.655739 631.835 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3814.9 - 9.51E+07 - - - 0.2544 - 2.593 0.645 - 423.7 1 2 0 0.0003 12 0 0 0 5.66E+08 5.53E+07 - - - 6.3119 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.20839.20839.2 0.00997 18-Nov R.LGGIAYFLSR.L "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1095.6077 1.61 62057 20839 2 1095.60757 548.8111 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 8.75 3815 - 3.15E+06 - - - -0.1004 - 2.255 0.348 - 418.9 1 2 0 -0.0001 10 0 0 0 1.43E+07 8.85E+06 - - - 3.881 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20840.20840.2 0.00146 20-Nov R.NTISLLVAGLK.K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1127.6914 1.38 62058 20840 2 1127.691896 564.853 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.75 3815.1 - 4.99E+06 - - - 0.431 - 2.288 0.36 - 459 1 2 0 0.0005 11 0 0 0 1.77E+07 1.29E+07 - - - 3.9389 1 230117_WJC_METTL3_WT_vs_EV_F07.20841.20841.2 0.000317 16-Sep R.FYNLVLLPR[166.11].V "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1143.668 1.09 62059 20841 2 1143.667818 572.8413 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 3815.1 - 4.23E+06 - - - -0.1469 - 2.045 0.601 - 346.6 1 2 0 -0.0002 9 0 0 0 5.88E+07 5.42E+07 - - - 5.5496 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20842.20842.2 0.0236 20-Oct K.IFGVTTLDIVR[166.11].A "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1242.7211 1.23 62060 20842 2 1242.722424 622.3678 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 5.84 3815.2 - 4.21E+06 - - - 1.0308 - 1.884 0.41 - 279.5 1 2 0 0.0013 11 0 0 0 4.08E+07 3.32E+07 - - - 3.7823 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20843.20843.2 3.39E-05 16-Sep R.FYNLVLLPR.V "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1133.6597 1.09 62061 20843 2 1133.659789 567.8371 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 3815.2 - 4.09E+06 - - - 0.0644 - 1.908 0.467 - 324.7 1 2 0 0.0001 9 0 0 0 5.88E+07 5.42E+07 - - - 4.3593 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20844.20844.2 0.000169 20-Dec K.FLFVDADQIVR.T sp|Q9NYU2|UGGG1_HUMAN 1 1321.703 8.97 62062 20844 2 1321.704045 661.8588 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.21 3815.3 - 2.36E+06 - - - 0.7627 - 2.238 0.388 - 500.9 1 2 0 0.001 11 0 0 0 5.46E+07 6.08E+06 - - - 4.0857 1 230117_WJC_METTL3_WT_vs_EV_F07.20845.20845.2 2.56E-08 15/22 R.VPDGMVGLIIGR.G "sp|Q92945|FUBP2_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 1225.6853 2.46 62063 20845 2 1225.687176 613.8499 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.81 3815.4 - 1.78E+06 - - - 1.5485 - 2.584 0.639 - 1027.8 1 2 0 0.0019 12 0 0 0 3.59E+07 1.46E+07 - - - 6.2579 0.985 230117_WJC_METTL3_WT_vs_EV_F07.20846.20846.2 0.00223 18-Nov K.YSDIDIILLK[136.11].G "sp|Q92973|TNPO1_HUMAN,tr|A0A7P0T9C0|A0A7P0T9C0_HUMAN,tr|A0A7P0TBF0|A0A7P0TBF0_HUMAN,tr|A0A7P0T944|A0A7P0T944_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 5 1199.6893 1.12 62064 20846 2 1199.683651 600.8519 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 4.21 3815.5 - 1.18E+06 - - - -4.7012 - 1.819 0.324 - 227.5 1 2 0 -0.0056 10 0 0 0 1.73E+07 1.55E+07 - - - 3.1023 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.20848.20848.2 1.31 16-Aug K.TLLEILDGK[136.11].L "sp|Q86YM7|HOME1_HUMAN,tr|Q86YM6|Q86YM6_HUMAN" 2 1008.5947 0.92 62066 20848 2 1008.596018 505.3046 Homer protein homolog 1 OS=Homo sapiens OX=9606 GN=HOMER1 PE=1 SV=2 4.37 3815.7 - 794566 - - - 1.3444 - 1.523 0.297 - 164.5 1 2 0 0.0014 9 0 0 0 1.92E+06 2.09E+06 - - - 2.4513 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.20850.20850.2 0.487 16-Aug K.VLLYLLSPR[166.11].D sp|Q15397|PUM3_HUMAN 1 1082.6727 0.99 62068 20850 2 1082.672687 542.3436 Pumilio homolog 3 OS=Homo sapiens OX=9606 GN=PUM3 PE=1 SV=3 8.72 3815.9 - 654336 - - - -0.0462 - 1.409 0.316 - 136.9 1 2 0 0 9 0 0 0 4.26E+06 4.29E+06 - - - 2.3669 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.20855.20855.2 5.40E-05 18-Oct K.FSDFLLDPYK.Y sp|Q9UIG0|BAZ1B_HUMAN 1 1243.6125 1.14 62071 20855 2 1243.613896 622.8135 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 4.21 3816.6 - 701092 - - - 1.1298 - 1.467 0.453 - 193.7 1 2 0 0.0014 10 0 0 0 1.08E+07 9.46E+06 - - - 3.4561 1 230117_WJC_METTL3_WT_vs_EV_F07.20857.20857.2 0.000785 13/20 K.ILLTQENPFFR[166.11].K sp|Q08J23|NSUN2_HUMAN 1 1386.7535 2.06 62073 20857 2 1386.75499 694.384 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3816.8 - 608373 - - - 1.0701 - 2.72 0.485 - 706.7 1 2 0 0.0015 11 0 0 0 1.31E+08 6.35E+07 - - - 5.3297 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.20859.20859.2 0.0354 22-Oct R.FLPEFPSC[160.03]SLLK.E sp|Q9H9A6|LRC40_HUMAN 1 1436.7374 2.79 62075 20859 2 1436.735277 719.376 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.99 3817 - 387464 - - - -1.4596 - 1.602 0.356 - 285.4 1 2 0 -0.0021 12 0 0 0 1.25E+07 4.49E+06 - - - 2.9097 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.20860.20860.2 0.00199 14-Oct K.TFFLEALR.G "sp|Q9H0R4|HDHD2_HUMAN,tr|K7ER15|K7ER15_HUMAN" 2 995.544 1.75 62076 20860 2 995.545125 498.7793 Haloacid dehalogenase-like hydrolase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=HDHD2 PE=1 SV=1 5.66 3817.2 - 339143 - - - 1.113 - 1.747 0.451 - 370.9 1 2 0 0.0011 8 0 0 0 6.31E+06 3.60E+06 - - - 4.0543 0.9285 230117_WJC_METTL3_WT_vs_EV_F07.20861.20861.2 0.0306 20-Nov K.LTPLILK[136.11]PFGN.S "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1219.742 0.81 62077 20861 2 1219.742085 610.8783 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 8.75 3817.3 - 281567 - - - 0.0738 - 1.565 0.347 - 348.7 1 1 0 0.0001 11 0 0 0 2.98E+07 3.69E+07 - - - 2.8156 1 230117_WJC_METTL3_WT_vs_EV_F07.20870.20870.2 2.84E-06 24-Dec K.ILGVWDTAVSLGK.L sp|Q53RT3|APRV1_HUMAN 1 1357.7606 1256.3 62084 20870 2 1357.760037 679.8876 Retroviral-like aspartic protease 1 OS=Homo sapiens OX=9606 GN=ASPRV1 PE=1 SV=1 5.84 3818.4 - 4.69E+06 - - - -0.3793 - 2.46 0.562 - 439.5 1 2 0 -0.0005 13 0 0 0 1.80E+07 1.44E+04 - - - 5.5021 0.9226 230117_WJC_METTL3_WT_vs_EV_F07.20872.20872.2 0.00252 20-Dec K.LTPLILKPFGN.S "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1211.7278 0.81 62086 20872 2 1211.726091 606.8712 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 8.75 3818.5 - 4.30E+06 - - - -1.4063 - 1.879 0.456 - 491.5 1 1 0 -0.0017 11 0 0 0 2.98E+07 3.69E+07 - - - 4.1148 1 230117_WJC_METTL3_WT_vs_EV_F07.20873.20873.2 7.18E-08 17/28 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 1441.15 62087 20873 2 1658.905407 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3818.6 - 3.86E+06 - - - -2.2063 - 3.115 0.576 - 1107.9 1 2 0 -0.0037 15 0 0 0 3.47E+08 2.41E+05 - - - 6.0877 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.20877.20877.2 0.00019 14-Jul K.ETLLAMFK.Y sp|P26639|SYTC_HUMAN 1 951.5099 2.23 62091 20877 2 951.509214 476.7622 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 6.1 3819.1 - 1.77E+06 - - - -0.763 - 1.626 0.414 - 167.9 1 2 0 -0.0007 8 0 0 0 8.46E+06 3.79E+06 - - - 3.5647 1 230117_WJC_METTL3_WT_vs_EV_F07.20878.20878.2 1.64E-05 26-Dec K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.11 62092 20878 2 1416.835208 709.4289 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3819.2 - 956790 - - - -5.6167 - 2.641 0.537 - 523.5 1 2 0 -0.008 14 0 0 0 2.89E+08 2.61E+08 - - - 5.4419 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.20883.20883.2 0.00117 16-Aug R.GFAFVYFER[166.11].L sp|Q13595|TRA2A_HUMAN 1 1144.5581 0.83 62095 20883 2 1144.557639 573.2863 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3819.9 - 1.01E+07 - - - -0.4036 - 1.594 0.356 - 218.9 1 2 0 -0.0005 9 0 0 0 6.69E+07 8.09E+07 - - - 3.0191 1 230117_WJC_METTL3_WT_vs_EV_F07.20884.20884.2 0.000831 20-Nov K.LFTAESLIGLK[136.11].N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1198.7053 1.64 62096 20884 2 1198.705344 600.3599 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6 3819.9 - 4.69E+06 - - - 0.0576 - 2.088 0.489 - 357 1 2 0 0.0001 11 0 0 0 5.12E+07 3.12E+07 - - - 4.6443 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.20885.20885.3 9.95E-06 14/56 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 1011.57 62097 20885 3 1658.908507 553.977 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3819.9 - 9.72E+06 - - - -0.3376 - 2.848 0.493 - 269.1 1 2 0 -0.0006 15 0 0 0 1.76E+08 1.74E+05 - - - 6.7673 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.20886.20886.2 0.0343 16-Sep R.GFAFVYFER.L sp|Q13595|TRA2A_HUMAN 1 1134.5498 0.83 62098 20886 2 1134.549803 568.2822 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3820 - 9.02E+06 - - - -0.0247 - 1.615 0.359 - 311.5 1 2 0 0 9 0 0 0 6.69E+07 8.09E+07 - - - 3.0793 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.20887.20887.2 0.00138 20-Oct K.LFTAESLIGLK.N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1190.6911 1.64 62099 20887 2 1190.691148 596.3528 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6 3820 - 7.88E+06 - - - 0.0613 - 1.96 0.371 - 272.8 1 2 0 0.0001 11 0 0 0 5.12E+07 3.12E+07 - - - 3.6017 1 230117_WJC_METTL3_WT_vs_EV_F07.20888.20888.2 1.34E-05 18-Dec K.MPLIGLGTWK[136.11].S "sp|P14550|AK1A1_HUMAN,sp|P15121|ALDR_HUMAN,tr|V9GYG2|V9GYG2_HUMAN,tr|E9PCX2|E9PCX2_HUMAN,tr|Q5T621|Q5T621_HUMAN,tr|V9GYP9|V9GYP9_HUMAN,tr|E9PEF9|E9PEF9_HUMAN" 7 1122.6351 0.95 62100 20888 2 1122.636115 562.3248 Aldo-keto reductase family 1 member A1 OS=Homo sapiens OX=9606 GN=AKR1A1 PE=1 SV=3 8.5 3820.1 - 2.35E+06 - - - 0.9157 - 2.329 0.506 - 617.8 1 2 0 0.001 10 0 0 0 1.89E+07 1.99E+07 - - - 5.1379 1 230117_WJC_METTL3_WT_vs_EV_F07.20889.20889.2 1.19E-08 13/22 R.YGLFPANYVELR.Q sp|Q14247|SRC8_HUMAN 1 1440.7402 2.09 62101 20889 2 1440.737827 721.3774 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 6 3820.2 - 2.19E+06 - - - -1.6131 - 2.646 0.481 - 548.8 1 2 0 -0.0023 12 0 0 0 2.42E+07 1.16E+07 - - - 5.1532 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.20890.20890.2 0.016 16-Aug R.YLTVAAIFR[166.11].G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1062.6101 2.99 62102 20890 2 1062.609908 532.3123 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3820.4 - 1.50E+06 - - - -0.2146 - 1.96 0.338 - 210.7 1 2 0 -0.0002 9 0 0 0 2.66E+07 8.90E+06 - - - 3.4843 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.20891.20891.2 0.12 14-Jul R.VIFGLFGK.T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 879.5218 0.62 62103 20891 2 879.521787 440.7682 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.72 3820.5 - 1.24E+06 - - - -0.0432 - 1.447 0.301 - 137 1 2 0 0 8 0 0 0 3.00E+07 4.88E+07 - - - 2.3785 1 230117_WJC_METTL3_WT_vs_EV_F07.20892.20892.3 6.92E-07 17/56 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.39 62104 20892 3 1548.926093 517.3153 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3820.6 - 1.16E+06 - - - 1.3971 - 2.982 0.533 - 397.2 1 2 0 0.0022 15 0 0 0 1.08E+07 7.80E+06 - - - 7.3328 1 230117_WJC_METTL3_WT_vs_EV_F07.20893.20893.2 2.92E-08 15/26 K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.11 62105 20893 2 1408.829316 705.4218 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3820.8 - 1.10E+06 - - - 0.2484 - 2.882 0.501 - 907.6 1 2 0 0.0003 14 0 0 0 2.88E+08 2.60E+08 - - - 5.3975 1 230117_WJC_METTL3_WT_vs_EV_F07.20894.20894.2 4.11E-05 22-Dec R.YGLFPANYVELR[166.11].Q sp|Q14247|SRC8_HUMAN 1 1450.7484 2.09 62106 20894 2 1450.744879 726.3815 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 6 3820.9 - 989107 - - - -2.4415 - 2.503 0.503 - 447 1 2 0 -0.0035 12 0 0 0 2.42E+07 1.16E+07 - - - 5.1691 0.9932 230117_WJC_METTL3_WT_vs_EV_F07.20896.20896.2 0.00346 20-Jul R.ALQFPPEGWLR.L "sp|Q96HS1|PGAM5_HUMAN,tr|F5GXG4|F5GXG4_HUMAN" 2 1312.6928 -1 62108 20896 2 1312.68855 657.3537 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 6.05 3821.1 - 516280 - - - -3.243 - 1.666 0.343 - 175.5 1 2 0 -0.0043 11 0 0 0 0.00E+00 0.00E+00 - - - 2.9539 1 230117_WJC_METTL3_WT_vs_EV_F07.20900.20900.2 1.52E-05 16-Nov R.YLTVAAIFR.G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1052.6019 2.99 62110 20900 2 1052.600221 527.3082 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3821.7 - 2.54E+06 - - - -1.5628 - 1.965 0.512 - 391 1 2 0 -0.0016 9 0 0 0 2.66E+07 8.90E+06 - - - 4.7764 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.20901.20901.2 0.00819 16-Sep K.IGFPWSEIR[166.11].N "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 1113.5847 0.64 62111 20901 2 1113.583742 557.7996 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 6 3821.8 - 1.26E+06 - - - -0.8154 - 1.619 0.321 - 220 1 2 0 -0.0009 9 0 0 0 1.96E+07 3.07E+07 - - - 2.8055 0.9606 230117_WJC_METTL3_WT_vs_EV_F07.20903.20903.2 0.00313 20-Dec M.LAVDAVIAELK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1140.6754 1.72 62113 20903 2 1140.675434 571.345 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.37 3822 - 691921 - - - 0.0079 - 1.9 0.408 - 287.3 1 1 0 0 11 0 0 0 8.57E+06 4.99E+06 - - - 3.7909 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.20905.20905.3 6.51E-07 14/52 K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.09 62115 20905 3 1408.827823 470.6169 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3822.3 - 449866 - - - -0.8113 - 2.893 0.531 - 257.2 1 2 0 -0.0011 14 0 0 0 3.42E+07 3.15E+07 - - - 7.2829 0.9998 230117_WJC_METTL3_WT_vs_EV_F07.20906.20906.3 0.000569 Nov-52 K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.09 62116 20906 3 1416.841089 473.2883 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3822.4 - 419923 - - - -1.4659 - 2.452 0.443 - 157.2 1 2 0 -0.0021 14 0 0 0 3.42E+07 3.15E+07 - - - 5.862 0.9948 230117_WJC_METTL3_WT_vs_EV_F07.20907.20907.2 0.0276 12-Jun K.YPVWLWK.R "sp|Q13084|RM28_HUMAN,tr|A2IDC6|A2IDC6_HUMAN,tr|A2IDC7|A2IDC7_HUMAN,tr|Q4TT37|Q4TT37_HUMAN" 4 990.5327 0.6 62117 20907 2 990.531281 496.2736 "39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4" 8.59 3822.6 - 380217 - - - -1.4568 - 1.374 0.267 - 144.1 1 2 0 -0.0014 7 0 0 0 6.99E+06 1.16E+07 - - - 2.0193 0.9959 230117_WJC_METTL3_WT_vs_EV_F07.20909.20909.2 0.89 22-Aug R.LTVLLPLAAAER[166.11].D sp|Q8IZ52|CHSS2_HUMAN 1 1275.779 1.22 62119 20909 2 1275.779714 638.8968 Chondroitin sulfate synthase 2 OS=Homo sapiens OX=9606 GN=CHPF PE=1 SV=2 6 3822.8 - 235453 - - - 0.5651 - 1.623 0.124 - 140.5 1 2 0 0.0007 12 0 0 0 5.25E+06 4.30E+06 - - - 1.2309 0.9926 230117_WJC_METTL3_WT_vs_EV_F07.20910.20910.2 0.318 14-Sep K.MILELFSK.V "sp|P78417|GSTO1_HUMAN,tr|Q5TA01|Q5TA01_HUMAN,tr|Q5TA02|Q5TA02_HUMAN" 3 979.5412 0.47 62120 20910 2 979.541304 490.7779 Glutathione S-transferase omega-1 OS=Homo sapiens OX=9606 GN=GSTO1 PE=1 SV=2 5.75 3823 - 221012 - - - 0.0653 - 1.673 0.047 - 277 1 2 0 0.0001 8 0 0 0 1.50E+06 3.22E+06 - - - 0.9402 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.20911.20911.2 0.000967 18-Oct K.IPGLLGVFQK[136.11].L sp|P55060|XPO2_HUMAN 1 1078.663 1.7 62121 20911 2 1078.660568 540.3388 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 8.75 3823.1 - 219068 - - - -2.2704 - 1.997 0.382 - 249.3 1 2 0 -0.0024 10 0 0 0 9.94E+06 5.85E+06 - - - 3.7923 1 230117_WJC_METTL3_WT_vs_EV_F07.20912.20912.2 2.25E-08 15/30 K.LPPPLSAPVAGLAALK.A sp|Q14781|CBX2_HUMAN 1 1513.9232 1.64 62122 20912 2 1513.927142 757.9689 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.75 3823.2 - 192290 - - - 2.6032 - 2.501 0.58 - 558.6 1 2 0 0.0039 16 0 0 0 8.41E+06 5.12E+06 - - - 5.5774 1 230117_WJC_METTL3_WT_vs_EV_F07.20913.20913.2 1.23E-09 18/34 K.ILDSFAAAPVPTTTLVLK.S sp|P18583|SON_HUMAN 1 1856.0659 1.53 62123 20913 2 1856.07127 929.0402 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3823.3 - 180181 - - - 2.8921 - 3.362 0.612 - 634.6 1 2 0 0.0054 18 0 0 0 4.92E+07 3.22E+07 - - - 6.5406 1 230117_WJC_METTL3_WT_vs_EV_F07.20916.20916.2 5.95E-11 21/34 K.ILDSFAAAPVPTTTLVLK[136.11].S sp|P18583|SON_HUMAN 1 1864.0801 1.53 62126 20916 2 1864.078539 933.0473 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3823.7 - 143276 - - - -0.8385 - 3.682 0.627 - 948.1 1 2 0 -0.0016 18 0 0 0 4.92E+07 3.22E+07 - - - 6.8761 1 230117_WJC_METTL3_WT_vs_EV_F07.20917.20917.2 8.40E-07 Sep-32 R.FINPAIVSPYEAGILDK.K "sp|P21359|NF1_HUMAN,tr|J3KSB5|J3KSB5_HUMAN,tr|H0Y465|H0Y465_HUMAN" 3 1845.9877 11.48 62127 20917 2 1845.98241 924.0011 Neurofibromin OS=Homo sapiens OX=9606 GN=NF1 PE=1 SV=2 4.37 3823.9 - 129720 - - - -2.8391 - 2.542 0.536 - 171.6 1 2 0 -0.0052 17 0 0 0 1.18E+06 1.03E+05 - - - 5.292 0.8837 230117_WJC_METTL3_WT_vs_EV_F07.20926.20926.3 0.242 13/68 K.ILDSFAAAPVPTTTLVLK.S sp|P18583|SON_HUMAN 1 1856.0659 0.43 62133 20926 3 1856.064448 619.6959 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3824.9 - 1.20E+06 - - - -0.7834 - 1.091 0.148 - 72.3 1 2 0 -0.0015 18 0 0 0 8.70E+06 2.01E+07 - - - 0.4065 0.9943 230117_WJC_METTL3_WT_vs_EV_F07.20931.20931.2 0.334 16-Aug K.IELPELFDR.G "sp|Q9Y2Z4|SYYM_HUMAN,tr|H0YHS6|H0YHS6_HUMAN" 2 1130.5972 2.11 62136 20931 2 1130.594194 566.3059 "Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2" 4.14 3825.6 - 1.00E+06 - - - -2.6367 - 1.888 0.248 - 272.8 1 2 0 -0.003 9 0 0 0 1.67E+07 7.95E+06 - - - 2.7104 1 230117_WJC_METTL3_WT_vs_EV_F07.20934.20934.2 4.79E-07 20-Sep R.GGYFDEFGIIR.D "sp|P11413|G6PD_HUMAN,tr|E7EM57|E7EM57_HUMAN,tr|E7EUI8|E7EUI8_HUMAN" 3 1272.6139 5.4 62139 20934 2 1272.608023 637.3142 Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4 4.37 3825.9 - 1.88E+06 - - - -4.6086 - 1.768 0.559 - 176.8 1 2 0 -0.0059 11 0 0 0 7.33E+06 1.36E+06 - - - 4.7095 0.9169 230117_WJC_METTL3_WT_vs_EV_F07.20938.20938.2 0.000511 20-Oct D.GMVPFVFVGTK[136.11].E "sp|P51114|FXR1_HUMAN,sp|Q06787|FMR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 9 1188.6457 0.51 62143 20938 2 1188.644686 595.3301 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 8.75 3826.4 - 1.62E+06 - - - -0.8127 - 1.735 0.375 - 363.5 1 1 0 -0.001 11 0 0 0 3.85E+06 7.51E+06 - - - 3.3011 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.20939.20939.2 0.00226 16-Sep K.QYGFFSYLR.E sp|Q8IY18|SMC5_HUMAN 1 1179.5713 2.46 62144 20939 2 1179.568983 590.7929 Structural maintenance of chromosomes protein 5 OS=Homo sapiens OX=9606 GN=SMC5 PE=1 SV=2 8.59 3826.5 - 1.51E+06 - - - -1.96 - 1.589 0.466 - 229.8 1 2 0 -0.0023 9 0 0 0 3.81E+06 1.55E+06 - - - 3.8219 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.20942.20942.2 0.00108 26-Dec R.LFLVGSSLNGFGTR.S "sp|Q6PIY7|GLD2_HUMAN,tr|D6RAF2|D6RAF2_HUMAN" 2 1466.7882 2.03 62147 20942 2 1466.784328 734.4014 Poly(A) RNA polymerase GLD2 OS=Homo sapiens OX=9606 GN=TENT2 PE=1 SV=1 9.75 3826.9 - 368237 - - - -2.6152 - 2.15 0.422 - 414.3 1 2 0 -0.0038 14 0 0 0 5.67E+06 2.80E+06 - - - 4.0776 1 230117_WJC_METTL3_WT_vs_EV_F07.20943.20943.2 7.63E-07 14/24 K.MVFINNIALAQIK[136.11].N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1481.852 0.85 62148 20943 2 1481.849103 741.9333 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3827 - 198580 - - - -1.9253 - 2.815 0.571 - 634.9 1 2 0 -0.0029 13 0 0 0 1.31E+07 1.54E+07 - - - 5.9138 0.9923 230117_WJC_METTL3_WT_vs_EV_F07.20944.20944.2 0.000958 30-Nov K.LPPPLSAPVAGLAALK[136.11].A sp|Q14781|CBX2_HUMAN 1 1521.9374 1.68 62149 20944 2 1521.931848 761.976 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.75 3827.2 - 937823 - - - -3.6486 - 1.548 0.407 - 154.5 1 2 0 -0.0056 16 0 0 0 6.75E+06 4.01E+06 - - - 3.1197 1 230117_WJC_METTL3_WT_vs_EV_F07.20946.20946.2 1.75E-14 23/30 R.TPEQVAEEEYLLQELR.K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1945.9633 1.39 62151 20946 2 1945.96282 973.9889 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3827.4 - 311762 - - - -0.24 - 4.555 0.688 - 1948.1 1 2 0 -0.0005 16 0 0 0 4.68E+06 3.37E+06 - - - 7.8501 1 230117_WJC_METTL3_WT_vs_EV_F07.20951.20951.2 8.62E-09 15/24 K.MVFINNIALAQIK.N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1473.8378 0.85 62154 20951 2 1473.831933 737.9262 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3828 - 5.46E+06 - - - -3.9509 - 3.002 0.603 - 734.2 1 2 0 -0.0058 13 0 0 0 1.31E+07 1.54E+07 - - - 6.3143 0.9969 230117_WJC_METTL3_WT_vs_EV_F07.20952.20952.2 0.0128 14-Oct K.EALLELLR[166.11].L sp|Q13895|BYST_HUMAN 1 965.5785 0.9 62155 20952 2 965.575689 483.7965 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3828.1 - 4.73E+06 - - - -2.9133 - 2.104 0.367 - 380.9 2 2 0 -0.0028 8 0 0 0 8.31E+06 9.22E+06 - - - 3.8597 0.9966 230117_WJC_METTL3_WT_vs_EV_F07.20953.20953.2 0.0145 14-Sep K.EALLELLR.L sp|Q13895|BYST_HUMAN 1 955.5702 0.9 62156 20953 2 955.566942 478.7924 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3828.2 - 4.48E+06 - - - -3.443 - 2.141 0.418 - 305.5 1 2 0 -0.0033 8 0 0 0 8.31E+06 9.22E+06 - - - 4.4233 1 230117_WJC_METTL3_WT_vs_EV_F07.20954.20954.3 2.09E-09 16/60 R.TPEQVAEEEYLLQELR.K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1945.9633 1.34 62157 20954 3 1945.958433 649.6617 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3828.4 - 3.45E+06 - - - -2.4944 - 3.044 0.572 - 352 1 2 0 -0.0049 16 0 0 0 6.87E+06 5.13E+06 - - - 7.7721 0.999 230117_WJC_METTL3_WT_vs_EV_F07.20955.20955.2 0.000141 18-Nov K.LWNEVLASLK.D "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 4 1171.6601 1.36 62158 20955 2 1171.659092 586.8373 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 6 3828.5 - 3.19E+06 - - - -0.8689 - 1.789 0.397 - 269.7 1 2 0 -0.001 10 0 0 0 7.71E+06 5.68E+06 - - - 3.5965 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.20956.20956.2 1.01E-05 18-Oct R.QALTDFLLAR.K "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1146.6397 0.94 62159 20956 2 1146.636728 574.3271 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.84 3828.6 - 2.88E+06 - - - -2.5989 - 2.275 0.322 - 328.2 1 2 0 -0.003 10 0 0 0 5.33E+06 5.64E+06 - - - 3.7128 0.992 230117_WJC_METTL3_WT_vs_EV_F07.20957.20957.2 0.00348 20-Dec K.ELGIWEPLAVK.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1253.702 11.11 62160 20957 2 1253.696789 627.8583 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3828.8 - 2.68E+06 - - - -4.1358 - 2.193 0.32 - 500.6 1 2 0 -0.0052 11 0 0 0 1.56E+08 1.41E+07 - - - 3.5272 1 230117_WJC_METTL3_WT_vs_EV_F07.20958.20958.2 3.71E-16 22/30 R.TPEQVAEEEYLLQELR.K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1945.9633 1.39 62161 20958 2 1945.955346 973.9889 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3828.9 - 2.58E+06 - - - -4.0808 - 4.412 0.659 - 1752.3 1 2 0 -0.0079 16 0 0 0 4.68E+06 3.37E+06 - - - 7.5552 1 230117_WJC_METTL3_WT_vs_EV_F07.20959.20959.3 7.79E-09 19/60 R.TPEQVAEEEYLLQELR[166.11].K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1955.9716 1.42 62162 20959 3 1955.963928 652.9978 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3829 - 2.47E+06 - - - -3.9004 - 3.056 0.581 - 439.7 1 2 0 -0.0076 16 0 0 0 7.28E+06 5.13E+06 - - - 7.8818 1 230117_WJC_METTL3_WT_vs_EV_F07.20960.20960.2 0.000204 18-Oct R.QALTDFLLAR[166.11].K "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1156.648 0.94 62163 20960 2 1156.645655 579.3313 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.84 3829.1 - 2.27E+06 - - - -2.0084 - 2.337 0.455 - 373.8 1 2 0 -0.0023 10 0 0 0 5.33E+06 5.64E+06 - - - 4.7703 1 230117_WJC_METTL3_WT_vs_EV_F07.20961.20961.2 6.12E-07 15/30 R.TPEQVAEEEYLLQELR[166.11].K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1955.9716 -1 62164 20961 2 1955.965966 978.9931 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3829.2 - 2.12E+06 - - - -2.8584 - 2.126 0.611 - 317.9 1 2 0 -0.0056 16 0 0 0 0.00E+00 0.00E+00 - - - 5.4064 0.988 230117_WJC_METTL3_WT_vs_EV_F07.20962.20962.2 0.289 14-Sep K.LLELLWNK.Y "sp|Q92905|CSN5_HUMAN,tr|E5RHH5|E5RHH5_HUMAN" 2 1027.6066 1.38 62165 20962 2 1027.604347 514.8106 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 6 3829.4 - 2.09E+06 - - - -2.209 - 1.706 0.141 - 232.7 1 2 0 -0.0023 8 0 0 0 7.09E+06 5.12E+06 - - - 1.6927 1 230117_WJC_METTL3_WT_vs_EV_F07.20965.20965.2 2.01E-07 15/24 K.VLGTAFDPFLGGK.N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1320.7078 9.43 62168 20965 2 1320.703774 661.3612 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3829.7 - 1.39E+06 - - - -3.0393 - 2.459 0.573 - 568.8 1 2 0 -0.004 13 0 0 0 6.28E+07 6.65E+06 - - - 5.5812 0.9924 230117_WJC_METTL3_WT_vs_EV_F07.20967.20967.2 0.000513 26-Nov K.VLFLLGADGGC[160.03]ITR.Q "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1490.7915 1.38 62170 20967 2 1490.78532 746.403 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 5.8 3830 - 1.03E+06 - - - -4.1689 - 2.108 0.369 - 413 1 2 0 -0.0062 14 0 0 0 6.37E+06 4.60E+06 - - - 3.6359 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.20970.20970.2 0.00779 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 2925.33 62172 20970 2 1603.759411 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3830.4 - 1.57E+08 - - - -2.824 - 1.868 0.481 - 226.6 1 2 0 -0.0045 12 0 0 0 9.42E+09 3.22E+06 - - - 4.2364 0.9896 230117_WJC_METTL3_WT_vs_EV_F07.20971.20971.2 0.0112 16-Jul K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 999 62173 20971 2 1014.535985 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 3830.5 - 48579.4 - - - 1.3898 - 1.582 0.029 - 101.1 2 2 0 0.0014 9 0 0 0 5.84E+08 0.00E+00 - - - 0.4473 1 230117_WJC_METTL3_WT_vs_EV_F07.20974.20974.2 0.00426 13/22 R.LALFNPDVC[160.03]WDR.N sp|O00483|NDUA4_HUMAN 1 1504.7133 -1 62176 20974 2 1504.714517 753.3639 Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1 4.21 3830.9 - 595272 - - - 0.8194 - 2.598 0.428 - 674.4 1 2 0 0.0012 12 0 0 0 0.00E+00 0.00E+00 - - - 4.7139 1 230117_WJC_METTL3_WT_vs_EV_F07.20975.20975.2 9.80E-08 14/30 R.IASLPVEVQEVSLLDK.L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1738.9717 3.37 62177 20975 2 1738.97207 870.4931 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.14 3831.1 - 562468 - - - 0.2317 - 2.66 0.564 - 464.7 1 2 0 0.0004 16 0 0 0 8.02E+06 2.38E+06 - - - 5.6118 1 230117_WJC_METTL3_WT_vs_EV_F07.20976.20976.2 3.74E-09 13/26 K.NLPIYSEEIVEMYK.G "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1726.8488 -1 62178 20976 2 1726.848548 864.4317 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3831.2 - 507982 - - - -0.1315 - 2.865 0.587 - 379.7 1 2 0 -0.0002 14 0 0 0 0.00E+00 0.00E+00 - - - 6.0179 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.20977.20977.2 0.00192 20-Dec K.ELGIWEPLAVK[136.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1261.7162 11.11 62179 20977 2 1261.713927 631.8654 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3831.3 - 472601 - - - -1.7809 - 2.002 0.342 - 464.5 1 2 0 -0.0022 11 0 0 0 1.56E+08 1.41E+07 - - - 3.4441 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.20978.20978.2 0.000946 30-Oct R.LIADLGSTSITNLGFR[166.11].D sp|Q92520|FAM3C_HUMAN 1 1686.918 -1 62180 20978 2 1686.912816 844.4663 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 5.84 3831.4 - 455446 - - - -3.076 - 2.146 0.443 - 243.4 1 2 0 -0.0052 16 0 0 0 0.00E+00 0.00E+00 - - - 4.1887 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.20981.20981.2 5.95E-05 22-Nov R.LALFNPDVC[160.03]WDR[166.11].N sp|O00483|NDUA4_HUMAN 1 1514.7216 -1 62183 20981 2 1514.726209 758.3681 Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1 4.21 3831.8 - 330987 - - - 3.0732 - 1.889 0.354 - 459.8 1 2 0 0.0047 12 0 0 0 0.00E+00 0.00E+00 - - - 3.3277 1 230117_WJC_METTL3_WT_vs_EV_F07.20982.20982.2 0.000255 20-Dec R.QLLEEMLTSYR.L sp|O75688|PPM1B_HUMAN 1 1381.6912 0.5 62184 20982 2 1381.687578 691.8529 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3832 - 246406 - - - -2.5867 - 2.532 0.527 - 717.4 1 2 0 -0.0036 11 0 0 0 7.18E+06 1.44E+07 - - - 5.4455 1 230117_WJC_METTL3_WT_vs_EV_F07.20983.20983.2 0.00174 13/24 K.ALVLANPEVSLWR.K "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 1466.8245 -1 62185 20983 2 1466.824105 734.4196 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6.05 3832.1 - 243261 - - - -0.3027 - 2.548 0.437 - 654.4 1 2 0 -0.0004 13 0 0 0 0.00E+00 0.00E+00 - - - 4.669 1 230117_WJC_METTL3_WT_vs_EV_F07.20985.20985.2 2.42E-06 13/24 K.NIPMTLELLQSTR[166.11].L "sp|P23193|TCEA1_HUMAN,tr|E5RJ93|E5RJ93_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN,tr|E5RIS7|E5RIS7_HUMAN" 4 1524.8209 -1 62187 20985 2 1524.821965 763.4177 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 6 3832.4 - 181238 - - - 0.6761 - 2.342 0.526 - 552 1 2 0 0.001 13 0 0 0 0.00E+00 0.00E+00 - - - 5.1098 1 230117_WJC_METTL3_WT_vs_EV_F07.20986.20986.2 2.45E-05 15/24 K.LLEQALVIEEQLR.R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1552.8825 -1 62188 20986 2 1552.883289 777.4485 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3832.5 - 135249 - - - 0.5351 - 2.976 0.421 - 882.3 1 2 0 0.0008 13 0 0 0 0.00E+00 0.00E+00 - - - 4.9493 1 230117_WJC_METTL3_WT_vs_EV_F07.20991.20991.3 4.29E-10 21/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 7425.88 62192 20991 3 1603.76327 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3833.1 - 1.16E+07 - - - -0.4178 - 3.168 0.592 - 697.2 1 2 0 -0.0007 12 0 0 0 6.78E+08 9.13E+04 - - - 8.3363 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.20992.20992.2 0.00398 13/20 R.QLLEEMLTSYR[166.11].L sp|O75688|PPM1B_HUMAN 1 1391.6994 0.5 62193 20992 2 1391.697735 696.857 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3833.2 - 3.80E+06 - - - -1.2122 - 2.478 0.418 - 780.9 1 2 0 -0.0017 11 0 0 0 7.18E+06 1.44E+07 - - - 4.5827 1 230117_WJC_METTL3_WT_vs_EV_F07.20994.20994.2 1.38E-08 16/24 K.VLGTAFDPFLGGK[136.11].N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1328.722 14.34 62195 20994 2 1328.721345 665.3683 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3833.3 - 2.26E+06 - - - -0.4839 - 2.904 0.623 - 635.4 1 2 0 -0.0006 13 0 0 0 8.71E+07 6.07E+06 - - - 6.3784 1 230117_WJC_METTL3_WT_vs_EV_F07.20998.20998.2 0.00219 22-Dec K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 1.39 62199 20998 2 1314.790646 658.4028 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3833.7 - 1.49E+06 - - - -0.3636 - 2.272 0.474 - 509 1 2 0 -0.0005 12 0 0 0 7.38E+07 5.30E+07 - - - 4.7011 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.21001.21001.2 9.43E-05 13/20 K.TLPLFYGSIVR[166.11].F "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1274.7262 1.06 62202 21001 2 1274.725256 638.3704 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 8.41 3834 - 986662 - - - -0.7633 - 2.165 0.265 - 636.4 1 2 0 -0.001 11 0 0 0 3.65E+06 3.44E+06 - - - 3.0876 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21002.21002.2 2.57E-05 20-Dec K.LLPAITILGC[160.03]R.V "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 2 1225.7217 -1 62203 21002 2 1225.722367 613.8681 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 8.25 3834.2 - 718052 - - - 0.5735 - 2.096 0.403 - 471 1 2 0 0.0007 11 0 0 0 0.00E+00 0.00E+00 - - - 4.0193 1 230117_WJC_METTL3_WT_vs_EV_F07.21003.21003.2 9.02E-07 18-Nov K.GYGFVSFFNK.W "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN" 4 1164.5604 1.06 62204 21003 2 1164.558682 583.2875 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 8.59 3834.3 - 689030 - - - -1.4709 - 2.293 0.63 - 389.9 1 2 0 -0.0017 10 0 0 0 4.30E+06 4.05E+06 - - - 6.01 1 230117_WJC_METTL3_WT_vs_EV_F07.21006.21006.2 3.03E-10 17/28 K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 0.59 62207 21006 2 1521.873251 761.945 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3834.7 - 514805 - - - -1.42 - 3.296 0.629 - 862.1 1 2 0 -0.0022 15 0 0 0 1.15E+06 1.95E+06 - - - 6.6184 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.21007.21007.2 0.0198 20-Oct K.VPPPWLIAMQR.Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1306.722 1.31 62208 21007 2 1306.725099 654.3683 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3834.8 - 466665 - - - 2.3731 - 1.602 0.277 - 318.4 1 2 0 0.0031 11 0 0 0 2.15E+07 1.64E+07 - - - 2.3608 1 230117_WJC_METTL3_WT_vs_EV_F07.21010.21010.2 1.04E-05 15/26 K.LGLVGVNLTLDGVK.S "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 1396.829 -1 62211 21010 2 1396.828322 699.4218 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 3835.2 - 422066 - - - -0.461 - 2.862 0.46 - 730.8 1 2 0 -0.0006 14 0 0 0 0.00E+00 0.00E+00 - - - 5.0771 1 230117_WJC_METTL3_WT_vs_EV_F07.21012.21012.2 8.57E-09 13/28 K.TVAGQDAVIVLLGTR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1511.8671 -1 62212 21012 2 1511.866532 756.9408 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3835.4 - 0 - - - -0.4035 - 2.853 0.614 - 496.4 1 2 0 -0.0006 15 0 0 0 0.00E+00 0.00E+00 - - - 6.1533 0.9824 230117_WJC_METTL3_WT_vs_EV_F07.21015.21015.3 0.155 Jun-56 K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 -1 62215 21015 3 1521.875371 508.2991 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3835.6 - 0 - - - -0.0269 - 1.426 0.169 - 50.5 1 2 0 0 15 0 0 0 0.00E+00 0.00E+00 - - - 1.3502 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.21017.21017.3 0.0555 Aug-56 K.TVAGQDAVIVLLGTR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1511.8671 -1 62217 21017 3 1511.866635 504.963 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3835.7 - 0 - - - -0.3353 - 1.536 0.342 - 96.3 1 2 0 -0.0005 15 0 0 0 0.00E+00 0.00E+00 - - - 3.4727 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21022.21022.2 0.00113 24-Dec K.LLEQALVIEEQLR[166.11].R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1562.8907 -1 62222 21022 2 1562.89361 782.4526 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3836.2 - 376519 - - - 1.844 - 1.62 0.423 - 391.6 1 2 0 0.0029 13 0 0 0 0.00E+00 0.00E+00 - - - 3.4025 1 230117_WJC_METTL3_WT_vs_EV_F07.21027.21027.2 3.82E-06 13/30 R.LPC[160.03]IYLVDSGGAYLPR.Q "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJW5|A0A804HJW5_HUMAN,tr|A0A0G2JM88|A0A0G2JM88_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HIH3|A0A804HIH3_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|D6RDF7|D6RDF7_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HJW2|A0A804HJW2_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|D6R9R1|D6R9R1_HUMAN,tr|A0A804HHS4|A0A804HHS4_HUMAN,tr|A0A0S2Z5R4|A0A0S2Z5R4_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 16 1792.9182 -1 62227 21027 2 1792.921348 897.4664 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.83 3836.7 - 0 - - - 1.7603 - 2.305 0.505 - 245 1 2 0 0.0032 16 0 0 0 0.00E+00 0.00E+00 - - - 4.823 1 230117_WJC_METTL3_WT_vs_EV_F07.21031.21031.2 0.000173 14/22 K.LVTLPVSFAQLK[136.11].N sp|Q96AG4|LRC59_HUMAN 1 1322.8053 1.39 62229 21031 2 1322.805148 662.4099 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3837.1 - 1.66E+07 - - - -0.1331 - 2.393 0.527 - 649.5 1 2 0 -0.0002 12 0 0 0 7.38E+07 5.30E+07 - - - 5.2292 1 230117_WJC_METTL3_WT_vs_EV_F07.21033.21033.2 5.24E-09 15/24 R.LGSTIFVANLDFK.V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1423.7711 1.86 62231 21033 2 1423.771468 712.8928 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3837.3 - 2.86E+06 - - - 0.2465 - 3.151 0.552 - 940.4 1 2 0 0.0004 13 0 0 0 1.28E+07 6.91E+06 - - - 6.0636 1 230117_WJC_METTL3_WT_vs_EV_F07.21034.21034.2 6.08E-07 15/26 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.9 62232 21034 2 1669.894471 835.9552 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3837.4 - 2.80E+06 - - - -0.8737 - 2.501 0.594 - 729.4 1 2 0 -0.0015 14 0 0 0 9.35E+07 1.04E+08 - - - 5.7282 0.8779 230117_WJC_METTL3_WT_vs_EV_F07.21036.21036.2 0.0188 16-Jun R.FYTLIPHDF.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1151.5651 - 62234 21036 2 1151.565729 576.7898 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.08 3837.5 - 2.15E+06 - - - 0.5054 - 1.04 0.383 - 93.7 1 1 0 0.0006 9 0 0 0 - - - - - 1.9831 1 230117_WJC_METTL3_WT_vs_EV_F07.21039.21039.2 1.49E-09 14/26 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.9 62237 21039 2 1661.881969 831.9481 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3837.9 - 1.59E+06 - - - 0.1438 - 2.637 0.649 - 638.2 1 2 0 0.0002 14 0 0 0 9.35E+07 1.04E+08 - - - 6.2677 1 230117_WJC_METTL3_WT_vs_EV_F07.21040.21040.2 9.02E-08 14/24 R.LGSTIFVANLDFK[136.11].V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1431.7853 1.86 62238 21040 2 1431.785435 716.8999 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3838 - 1.48E+06 - - - 0.0824 - 2.989 0.522 - 823.7 1 2 0 0.0001 13 0 0 0 1.28E+07 6.91E+06 - - - 5.7066 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.21042.21042.2 0.00237 16-Aug R.MLYVWALC[160.03]R.D "sp|O43615|TIM44_HUMAN,tr|M0QXM9|M0QXM9_HUMAN" 2 1210.5991 -1 62240 21042 2 1210.600294 606.3068 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 7.98 3838.3 - 1.06E+06 - - - 0.9813 - 1.534 0.319 - 169.8 1 2 0 0.0012 9 0 0 0 0.00E+00 0.00E+00 - - - 2.6346 1 230117_WJC_METTL3_WT_vs_EV_F07.21045.21045.2 1.32E-07 18/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 62243 21045 2 1343.614072 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3838.6 - 860314 - - - 1.9425 - 3.018 0.539 - 1277.7 1 1 0 0.0026 10 0 0 0 1.05E+07 0.00E+00 - - - 6.1045 0.995 230117_WJC_METTL3_WT_vs_EV_F07.21050.21050.2 0.331 18-Sep K.ADLGALELWR.T sp|Q99523|SORT_HUMAN 1 1142.6084 49.37 62248 21050 2 1142.607933 572.3115 Sortilin OS=Homo sapiens OX=9606 GN=SORT1 PE=1 SV=3 4.37 3839.3 - 560292 - - - -0.4157 - 1.705 0.127 - 156.1 1 2 0 -0.0005 10 0 0 0 3.80E+06 7.70E+04 - - - 1.4682 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.21054.21054.2 0.000304 16-Sep K.TLDDLFPLR.S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1088.5866 1.89 62251 21054 2 1088.585646 545.3006 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.21 3839.6 - 841570 - - - -0.8856 - 1.976 0.294 - 270.6 1 2 0 -0.001 9 0 0 0 2.93E+07 1.55E+07 - - - 3.1826 0.9906 230117_WJC_METTL3_WT_vs_EV_F07.21055.21055.2 0.0272 16-Jun K.ITFLLQAIR.N "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1073.6597 1.33 62252 21055 2 1073.659876 537.8371 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 3839.7 - 1.05E+06 - - - 0.149 - 1.139 0.179 - 92 1 2 0 0.0002 9 0 0 0 1.83E+07 1.38E+07 - - - 0.7396 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.21057.21057.3 3.49E-05 Nov-52 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.9 62254 21057 3 1661.883343 554.9679 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3839.8 - 654910 - - - 0.9706 - 2.143 0.465 - 145.3 1 2 0 0.0016 14 0 0 0 1.05E+07 1.17E+07 - - - 5.7494 1 230117_WJC_METTL3_WT_vs_EV_F07.21063.21063.2 2.01E-05 20-Nov K.VAVFFGGLSIK.K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1136.6594 0.88 62258 21063 2 1136.658822 569.337 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3840.6 - 204534 - - - -0.4918 - 2.422 0.499 - 474.5 1 2 0 -0.0006 11 0 0 0 2.05E+07 2.32E+07 - - - 5.1195 0.9498 230117_WJC_METTL3_WT_vs_EV_F07.21074.21074.3 0.474 Jul-52 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.9 62266 21074 3 1669.896766 557.6393 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3842 - 1.49E+06 - - - 0.5006 - 1.166 0.142 - 56.8 1 2 0 0.0008 14 0 0 0 1.05E+07 1.17E+07 - - - 0.5311 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.21075.21075.2 0.104 16-Jul K.TLDDLFPLR[166.11].S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1098.5949 1.89 62267 21075 2 1098.59619 550.3047 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.21 3842 - 387737 - - - 1.1924 - 1.456 0.231 - 134.9 1 2 0 0.0013 9 0 0 0 2.93E+07 1.55E+07 - - - 1.8337 1 230117_WJC_METTL3_WT_vs_EV_F07.21077.21077.2 3.39E-07 20-Oct K.VLYVYDMLAGK[136.11].L "sp|Q9Y5J1|UTP18_HUMAN,tr|J3KSR7|J3KSR7_HUMAN" 2 1278.6773 0.9 62269 21077 2 1278.67973 640.3459 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 5.8 3842.2 - 0 - - - 1.8644 - 2.261 0.553 - 323.9 1 2 0 0.0024 11 0 0 0 6.14E+06 6.80E+06 - - - 5.3317 1 230117_WJC_METTL3_WT_vs_EV_F07.21079.21079.2 7.88E-07 24-Dec R.VLLFTDDVALVSK.A "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1418.8021 1.13 62271 21079 2 1418.801551 710.4083 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.21 3842.5 - 118491 - - - -0.3743 - 2.533 0.569 - 361.2 1 2 0 -0.0005 13 0 0 0 7.06E+06 6.24E+06 - - - 5.6288 1 230117_WJC_METTL3_WT_vs_EV_F07.21088.21088.2 0.0112 18-Dec R.MALLATVLGR.F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1043.6161 2.03 62278 21088 2 1043.615773 522.8153 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.5 3843.6 - 1.32E+06 - - - -0.3478 - 2.445 0.487 - 727.2 1 2 0 -0.0004 10 0 0 0 3.71E+07 1.83E+07 - - - 5.1334 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21089.21089.2 0.0231 18-Nov R.MALLATVLGR[166.11].F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1053.6244 2.03 62279 21089 2 1053.624102 527.8195 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.5 3843.7 - 596534 - - - -0.2885 - 2.095 0.422 - 600.4 1 2 0 -0.0003 10 0 0 0 3.71E+07 1.83E+07 - - - 4.2221 1 230117_WJC_METTL3_WT_vs_EV_F07.21096.21096.2 0.00266 18-Nov R.DFILPISDVR.A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|Q4VXM0|Q4VXM0_HUMAN,tr|Q4VXM1|Q4VXM1_HUMAN" 5 1173.6394 2.66 62286 21096 2 1173.640754 587.827 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.21 3844.6 - 577111 - - - 1.1758 - 2.267 0.491 - 536.5 1 2 0 0.0014 10 0 0 0 1.82E+07 6.84E+06 - - - 4.9517 0.9949 230117_WJC_METTL3_WT_vs_EV_F07.21097.21097.2 0.0166 14-Aug R.DFLLDIAR.Q "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 961.5233 1.25 62287 21097 2 961.520643 481.7689 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 3844.7 - 516184 - - - -2.7446 - 1.518 0.355 - 303.6 1 2 0 -0.0026 8 0 0 0 1.95E+07 1.56E+07 - - - 2.921 1 230117_WJC_METTL3_WT_vs_EV_F07.21098.21098.2 1.65E-05 24-Nov R.VLLFTDDVALVSK[136.11].A "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1426.8163 1.13 62288 21098 2 1426.818576 714.4154 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.21 3844.9 - 488927 - - - 1.6078 - 2.491 0.49 - 222.1 1 2 0 0.0023 13 0 0 0 7.06E+06 6.24E+06 - - - 5.0019 1 230117_WJC_METTL3_WT_vs_EV_F07.21101.21101.2 0.000399 14/24 K.AAILPTSIFLTNK[136.11].K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1395.8217 0.46 62291 21101 2 1395.820222 698.9181 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3845.3 - 450650 - - - -1.0603 - 2.327 0.478 - 520.6 1 2 0 -0.0015 13 0 0 0 1.72E+07 3.73E+07 - - - 4.7387 1 230117_WJC_METTL3_WT_vs_EV_F07.21103.21103.2 0.000203 24-Dec K.IAVPLIQGYTVLR[166.11].L sp|Q8IW92|GLBL2_HUMAN 1 1451.874 0.89 62293 21103 2 1451.880891 726.9443 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3845.5 - 250676 - - - 4.7766 - 2.278 0.491 - 552.1 1 2 0 0.0069 13 0 0 0 3.67E+06 4.11E+06 - - - 4.7784 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.21105.21105.2 0.00284 26-Oct R.WEGPLSVSVFAATK[136.11].E sp|O43505|B4GA1_HUMAN 1 1498.7911 0.79 62295 21105 2 1498.788776 750.4028 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 6 3845.8 - 218778 - - - -1.5706 - 2.054 0.393 - 268.4 1 2 0 -0.0024 14 0 0 0 2.04E+06 2.59E+06 - - - 3.7492 0.9998 230117_WJC_METTL3_WT_vs_EV_F07.21107.21107.3 2.90E-05 Nov-36 K.YRPLFDYFLK.C "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 1360.718 1.14 62297 21107 3 1360.715479 454.5799 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.5 3846 - 195196 - - - -1.8226 - 2.024 0.507 - 155.4 1 2 0 -0.0025 10 0 0 0 2.76E+06 2.43E+06 - - - 6.251 0.9951 230117_WJC_METTL3_WT_vs_EV_F07.21110.21110.2 0.00986 20-Jul K.VAVFFGGLSIK[136.11].K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1144.6736 0.88 62299 21110 2 1144.672124 573.3441 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3846.3 - 347068 - - - -1.2729 - 1.522 0.242 - 153.2 1 2 0 -0.0015 11 0 0 0 2.05E+07 2.32E+07 - - - 1.9642 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.21113.21113.2 0.00021 12-Aug K.YFLWVVK.F sp|P62993|GRB2_HUMAN 1 953.5375 2.78 62302 21113 2 953.537402 477.776 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 8.59 3846.5 - 656833 - - - -0.0766 - 1.407 0.339 - 201.3 1 2 0 -0.0001 7 0 0 0 5.45E+06 1.96E+06 - - - 2.6268 0.9654 230117_WJC_METTL3_WT_vs_EV_F07.21115.21115.2 0.155 20-Jul K.VPPPWLIAMQR[166.11].Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1316.7303 1.36 62304 21115 2 1316.728547 659.3724 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3846.6 - 514078 - - - -1.307 - 1.419 0.059 - 152.3 1 2 0 -0.0017 11 0 0 0 2.14E+07 1.58E+07 - - - 0.4229 1 230117_WJC_METTL3_WT_vs_EV_F07.21118.21118.2 3.21E-06 20-Nov K.VLYVYDMLAGK.L "sp|Q9Y5J1|UTP18_HUMAN,tr|J3KSR7|J3KSR7_HUMAN" 2 1270.6631 0.9 62307 21118 2 1270.661498 636.3388 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 5.8 3846.9 - 0 - - - -1.297 - 2.156 0.517 - 471.5 1 2 0 -0.0016 11 0 0 0 6.14E+06 6.80E+06 - - - 4.9374 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21121.21121.2 0.00231 24-Nov K.IAVPLIQGYTVLR.L sp|Q8IW92|GLBL2_HUMAN 1 1441.8657 0.89 62310 21121 2 1441.868747 721.9401 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3847.3 - 0 - - - 2.1229 - 1.878 0.365 - 406.4 1 2 0 0.0031 13 0 0 0 3.67E+06 4.11E+06 - - - 3.3534 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21129.21129.2 0.000173 13/20 R.FDEISFVNFAR.G sp|Q08945|SSRP1_HUMAN 1 1343.651 0.89 62316 21129 2 1343.65102 672.8328 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3848.2 - 1.42E+06 - - - 0.0141 - 1.944 0.486 - 441.7 1 2 0 0 11 0 0 0 6.20E+06 6.93E+06 - - - 4.4289 1 230117_WJC_METTL3_WT_vs_EV_F07.21131.21131.2 4.38E-05 24-Dec K.AAILPTSIFLTNK.K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1387.8075 0.46 62317 21131 2 1387.808258 694.911 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3848.4 - 3.36E+06 - - - 0.5447 - 2.271 0.517 - 347.3 1 2 0 0.0008 13 0 0 0 1.72E+07 3.72E+07 - - - 4.9644 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.21132.21132.2 0.178 16-Sep R.DLLFQALGR.T sp|Q9NSD9|SYFB_HUMAN 1 1031.5764 4.18 62318 21132 2 1031.578591 516.7955 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 5.84 3848.6 - 3.45E+06 - - - 2.1433 - 1.803 0.234 - 283 1 2 0 0.0022 9 0 0 0 1.38E+07 3.30E+06 - - - 2.4739 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.21135.21135.2 0.00854 14-Sep R.TLFGFLGK.L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 881.5011 1.49 62321 21135 2 881.501713 441.7578 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3848.9 - 1.74E+06 - - - 0.7067 - 1.209 0.365 - 208.5 1 2 0 0.0006 8 0 0 0 1.43E+07 9.59E+06 - - - 2.3091 1 230117_WJC_METTL3_WT_vs_EV_F07.21136.21136.2 5.06E-05 14/20 R.TSLGNVVLLLK.S "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1155.7227 1.61 62322 21136 2 1155.723969 578.8686 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 8.41 3849.1 - 1.70E+06 - - - 1.0894 - 2.653 0.425 - 578.2 1 2 0 0.0013 11 0 0 0 1.45E+07 9.05E+06 - - - 4.8191 1 230117_WJC_METTL3_WT_vs_EV_F07.21137.21137.2 0.000264 13/20 R.FDEISFVNFAR[166.11].G sp|Q08945|SSRP1_HUMAN 1 1353.6593 0.89 62323 21137 2 1353.659165 677.8369 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3849.2 - 1.67E+06 - - - -0.0783 - 2.402 0.467 - 744 1 2 0 -0.0001 11 0 0 0 6.20E+06 6.93E+06 - - - 4.8608 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.21139.21139.2 0.00899 14-Jul R.TLFGFLGK[136.11].L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 889.5153 1.56 62325 21139 2 889.515332 445.7649 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3849.5 - 1.40E+06 - - - 0.0472 - 1.313 0.433 - 147 1 2 0 0 8 0 0 0 1.41E+07 9.09E+06 - - - 3.0604 0.8794 230117_WJC_METTL3_WT_vs_EV_F07.21141.21141.2 0.02 14-Jul F.LFLWVTGR.A sp|Q86U44|MTA70_HUMAN 1 990.5651 999 62327 21141 2 990.56541 496.2898 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.75 3849.7 - 1.00E+06 - - - 0.3261 - 1.457 0.256 - 148.2 1 1 0 0.0003 8 0 0 0 3.60E+06 0.00E+00 - - - 2.0669 0.9969 230117_WJC_METTL3_WT_vs_EV_F07.21144.21144.2 0.87 16-Aug R.DLLFQALGR[166.11].T sp|Q9NSD9|SYFB_HUMAN 1 1041.5847 4.2 62330 21144 2 1041.586836 521.7996 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 5.84 3850.1 - 718654 - - - 2.0987 - 1.656 0.13 - 226.6 1 2 0 0.0022 9 0 0 0 1.42E+07 3.38E+06 - - - 1.4598 1 230117_WJC_METTL3_WT_vs_EV_F07.21149.21149.2 6.49E-07 22-Oct K.ITAEEMYDIFGK.Y sp|Q9Y3B4|SF3B6_HUMAN 1 1415.6643 2.01 62335 21149 2 1415.665646 708.8394 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.14 3850.8 - 581889 - - - 0.9734 - 2.204 0.579 - 311.9 1 2 0 0.0014 12 0 0 0 5.27E+06 2.62E+06 - - - 5.3964 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.21154.21154.2 0.376 14-Sep K.VALLDVFR.E "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 931.5491 2.89 62339 21154 2 931.549742 466.7818 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.81 3851.4 - 1.55E+06 - - - 0.687 - 1.975 0.251 - 433 1 2 0 0.0006 8 0 0 0 4.30E+07 1.49E+07 - - - 2.9472 1 230117_WJC_METTL3_WT_vs_EV_F07.21155.21155.2 2.18E-05 16-Oct R.DIVQFVPFR.E "sp|Q96FN4|CPNE2_HUMAN,sp|O75131|CPNE3_HUMAN,sp|O95741|CPNE6_HUMAN,sp|Q86YQ8|CPNE8_HUMAN,sp|Q8IYJ1|CPNE9_HUMAN,sp|Q9UBL6|CPNE7_HUMAN,sp|Q9HCH3|CPNE5_HUMAN,sp|Q96A23|CPNE4_HUMAN,tr|E7ENV7|E7ENV7_HUMAN" 9 1119.6077 2.31 62340 21155 2 1119.607633 560.8111 Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3 5.84 3851.5 - 1.54E+06 - - - -0.042 - 2.133 0.479 - 458.8 1 2 0 0 9 0 0 0 6.09E+06 2.63E+06 - - - 4.7705 0.9961 230117_WJC_METTL3_WT_vs_EV_F07.21156.21156.2 0.0536 14-Jul R.VFLWGSFR[166.11].D "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1020.5421 0.81 62341 21156 2 1020.542732 511.2783 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 9.72 3851.6 - 1.48E+06 - - - 0.6614 - 1.306 0.189 - 242.1 1 2 0 0.0007 8 0 0 0 2.99E+06 3.71E+06 - - - 1.2419 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.21157.21157.2 0.00112 14-Sep R.VFLWGSFR.D "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1010.5338 0.81 62342 21157 2 1010.533848 506.2742 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 9.72 3851.7 - 1.14E+06 - - - 0.0604 - 1.673 0.399 - 380.2 1 2 0 0.0001 8 0 0 0 2.99E+06 3.71E+06 - - - 3.5401 0.999 230117_WJC_METTL3_WT_vs_EV_F07.21158.21158.2 0.0288 16-Aug R.DIVQFVPFR[166.11].E "sp|Q96FN4|CPNE2_HUMAN,sp|O75131|CPNE3_HUMAN,sp|O95741|CPNE6_HUMAN,sp|Q86YQ8|CPNE8_HUMAN,sp|Q8IYJ1|CPNE9_HUMAN,sp|Q9UBL6|CPNE7_HUMAN,sp|Q9HCH3|CPNE5_HUMAN,sp|Q96A23|CPNE4_HUMAN,tr|E7ENV7|E7ENV7_HUMAN" 9 1129.616 2.31 62343 21158 2 1129.615191 565.8153 Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3 5.84 3851.8 - 910595 - - - -0.6719 - 1.75 0.372 - 306.6 1 2 0 -0.0008 9 0 0 0 6.09E+06 2.63E+06 - - - 3.4074 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.21160.21160.2 0.39 14-Aug K.VALLDVFR[166.11].E "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 941.5574 2.89 62345 21160 2 941.55723 471.786 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.81 3851.9 - 696852 - - - -0.1508 - 1.993 0.183 - 318.6 1 2 0 -0.0001 8 0 0 0 4.30E+07 1.49E+07 - - - 2.4725 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21161.21161.2 0.000574 20-Nov K.LLVSGFWGVAR.H "sp|Q9UBM7|DHCR7_HUMAN,tr|A0A804HI25|A0A804HI25_HUMAN,tr|A0A804HJQ7|A0A804HJQ7_HUMAN,tr|H0YE57|H0YE57_HUMAN" 4 1203.6764 3.2 62346 21161 2 1203.675885 602.8455 7-dehydrocholesterol reductase OS=Homo sapiens OX=9606 GN=DHCR7 PE=1 SV=1 9.75 3852 - 567655 - - - -0.4511 - 2.039 0.453 - 359.5 1 2 0 -0.0005 11 0 0 0 3.75E+06 1.17E+06 - - - 4.3141 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.21163.21163.2 0.00693 16-Aug K.YPENFFLLR[166.11].G "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|C9J9S3|C9J9S3_HUMAN,tr|E7ETD8|E7ETD8_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 12 1207.6265 1.25 62348 21163 2 1207.629372 604.8205 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 6 3852.3 - 559153 - - - 2.3658 - 1.487 0.39 - 172 1 2 0 0.0029 9 0 0 0 2.45E+06 1.95E+06 - - - 3.0685 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.21164.21164.2 4.40E-06 16-Oct K.YPENFFLLR.G "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|C9J9S3|C9J9S3_HUMAN,tr|E7ETD8|E7ETD8_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 12 1197.6182 1.7 62349 21164 2 1197.616966 599.8164 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 6 3852.4 - 491867 - - - -1.068 - 1.875 0.48 - 448.4 1 2 0 -0.0013 9 0 0 0 3.18E+06 1.87E+06 - - - 4.4045 1 230117_WJC_METTL3_WT_vs_EV_F07.21165.21165.2 0.281 14/20 K.LEDVLPLAFTR[166.11].L "sp|Q5SSJ5|HP1B3_HUMAN,tr|B0QZK4|B0QZK4_HUMAN,tr|Q5SWC8|Q5SWC8_HUMAN" 3 1282.7161 0.76 62350 21165 2 1282.716453 642.3653 Heterochromatin protein 1-binding protein 3 OS=Homo sapiens OX=9606 GN=HP1BP3 PE=1 SV=1 4.37 3852.5 - 479103 - - - 0.3079 - 2.548 0.415 - 715.4 1 2 0 0.0004 11 0 0 0 3.20E+06 4.19E+06 - - - 4.6363 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.21167.21167.2 1.98E-05 20-Nov R.WPDPEDLLTPR.W sp|Q8TAE8|G45IP_HUMAN 1 1337.6616 -1 62352 21167 2 1337.658295 669.8381 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.03 3852.7 - 314067 - - - -2.4453 - 1.799 0.501 - 376.2 1 2 0 -0.0033 11 0 0 0 0.00E+00 0.00E+00 - - - 4.329 1 230117_WJC_METTL3_WT_vs_EV_F07.21176.21176.2 2.02E-07 14/26 K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 15.19 62360 21176 2 1613.79876 807.9078 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3853.9 - 2.07E+06 - - - -1.4475 - 2.359 0.567 - 427 1 2 0 -0.0023 14 0 0 0 1.12E+09 7.38E+07 - - - 5.3818 1 230117_WJC_METTL3_WT_vs_EV_F07.21179.21179.3 6.20E-10 16/52 K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 14.82 62363 21179 3 1613.803595 538.941 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3854.3 - 767579 - - - 1.5485 - 2.855 0.516 - 383.5 1 2 0 0.0025 14 0 0 0 2.91E+08 1.97E+07 - - - 7.0801 0.8968 230117_WJC_METTL3_WT_vs_EV_F07.21180.21180.2 0.00171 20-Nov R.PLEVFMC[160.03]SVLK.R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1321.6774 17.04 62364 21180 2 1321.675083 661.846 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.38 3854.4 - 602886 - - - -1.7652 - 1.877 0.432 - 276.9 1 1 0 -0.0023 11 0 0 0 2.23E+07 1.31E+06 - - - 3.9344 1 230117_WJC_METTL3_WT_vs_EV_F07.21182.21182.2 5.04E-08 13/26 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 4.3 62366 21182 2 1535.792981 768.9025 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3854.7 - 507701 - - - 1.5946 - 2.476 0.538 - 469.8 1 2 0 0.0024 14 0 0 0 6.79E+07 1.58E+07 - - - 5.2891 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.21185.21185.2 5.56E-05 20-Oct K.DFPLSGYVELR.Y sp|O75489|NDUS3_HUMAN 1 1294.6558 1.96 62369 21185 2 1294.655373 648.3352 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 4.37 3855 - 377539 - - - -0.2927 - 1.781 0.411 - 317.4 1 2 0 -0.0004 11 0 0 0 4.34E+06 2.21E+06 - - - 3.6379 0.8722 230117_WJC_METTL3_WT_vs_EV_F07.21187.21187.2 0.0153 20-Sep R.PLEVFMC[160.03]SVLK[136.11].R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1329.6916 7.36 62371 21187 2 1329.690243 665.8531 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.38 3855.3 - 326047 - - - -1.0326 - 1.627 0.337 - 186.1 1 1 0 -0.0014 11 0 0 0 9.96E+06 1.35E+06 - - - 2.8464 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.21191.21191.2 0.00489 14-Aug R.FFFNLGVK[136.11].A sp|Q01804|OTUD4_HUMAN 1 978.5418 2.07 62375 21191 2 978.543067 490.2782 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 8.75 3855.8 - 241872 - - - 1.2549 - 1.332 0.345 - 143.3 1 2 0 0.0012 8 0 0 0 4.06E+06 1.96E+06 - - - 2.4534 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21197.21197.2 8.37E-06 20-Nov R.DSLIFLVDASK.A sp|P12956|XRCC6_HUMAN 1 1206.6496 0.94 62380 21197 2 1206.649768 604.3321 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.21 3856.5 - 4.10E+06 - - - 0.1359 - 2.312 0.434 - 387.5 1 2 0 0.0002 11 0 0 0 2.34E+07 2.49E+07 - - - 4.5138 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.21199.21199.3 3.23E-05 13/52 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 3.97 62382 21199 3 1535.79239 512.9375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3856.7 - 1.09E+06 - - - 1.2098 - 2.285 0.42 - 271.4 1 2 0 0.0019 14 0 0 0 1.57E+07 3.96E+06 - - - 5.4182 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.21200.21200.2 0.0897 14-Aug R.IPFTFWAR.Y sp|Q9Y5V3|MAGD1_HUMAN 1 1036.5494 1.3 62383 21200 2 1036.550309 519.282 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 9.75 3856.8 - 880709 - - - 0.8413 - 1.516 0.354 - 243.3 1 2 0 0.0009 8 0 0 0 8.30E+06 6.39E+06 - - - 2.9102 1 230117_WJC_METTL3_WT_vs_EV_F07.21203.21203.2 5.19E-06 26-Nov K.TFAPEEISAMVLTK[136.11].M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1543.8047 4.3 62386 21203 2 1543.798639 772.9096 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3857 - 533926 - - - -3.9467 - 2.133 0.551 - 260.8 1 2 0 -0.0061 14 0 0 0 6.79E+07 1.58E+07 - - - 5.0098 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21205.21205.2 0.000741 14-Aug R.FFFNLGVK.A sp|Q01804|OTUD4_HUMAN 1 970.5276 -1 62388 21205 2 970.528105 486.2711 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 8.75 3857.3 - 423356 - - - 0.4802 - 1.484 0.457 - 146.1 1 2 0 0.0005 8 0 0 0 0.00E+00 0.00E+00 - - - 3.6068 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21217.21217.2 2.82E-05 18-Nov R.WYEWLDPSIK.K sp|Q99459|CDC5L_HUMAN 1 1335.6499 1.2 62397 21217 2 1335.650293 668.8322 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3858.6 - 1.29E+06 - - - 0.265 - 1.836 0.465 - 399.7 1 2 0 0.0004 10 0 0 0 1.02E+07 8.52E+06 - - - 4.1713 1 230117_WJC_METTL3_WT_vs_EV_F07.21221.21221.2 2.77E-08 17/28 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 3.56 62401 21221 2 1700.899691 851.4565 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3858.8 - 255332 - - - 0.699 - 3.254 0.612 - 800.9 1 2 0 0.0012 15 0 0 0 3.58E+08 1.01E+08 - - - 6.4617 1 230117_WJC_METTL3_WT_vs_EV_F07.21224.21224.2 1.83E-07 17/28 K.VSALDLAVLDQVEAR.L "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 6 1597.8675 7.26 62404 21224 2 1597.874139 799.941 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.03 3859.1 - 0 - - - 4.1324 - 3.198 0.403 - 1182.9 1 2 0 0.0066 15 0 0 0 3.52E+06 4.85E+05 - - - 4.8736 1 230117_WJC_METTL3_WT_vs_EV_F07.21225.21225.2 1.52E-07 14/28 K.LLDTVDDMLANDIAR.L "sp|Q9H4M9|EHD1_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 3 1673.8294 -1 62405 21225 2 1673.829851 837.922 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 3.77 3859.2 - 0 - - - 0.2479 - 3.034 0.637 - 638.8 1 2 0 0.0004 15 0 0 0 0.00E+00 0.00E+00 - - - 6.4744 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21226.21226.3 0.00212 Sep-44 R.LLALLDALASHK[136.11].A "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 1271.7693 -1 62406 21226 3 1271.767606 424.9304 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6.74 3859.3 - 110639 - - - -1.3108 - 1.96 0.402 - 124.2 1 2 0 -0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 4.8867 1 230117_WJC_METTL3_WT_vs_EV_F07.21229.21229.2 3.31E-07 18/28 R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 3.56 62409 21229 2 1710.906414 856.4607 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3859.7 - 124946 - - - -0.2092 - 3.572 0.583 - 884.8 1 2 0 -0.0004 15 0 0 0 3.58E+08 1.01E+08 - - - 6.477 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.21230.21230.2 0.0692 24-Aug R.GLAFELVYSPAIK.D "sp|P78346|RPP30_HUMAN,tr|Q5VU11|Q5VU11_HUMAN,tr|Q5VU10|Q5VU10_HUMAN" 3 1406.781 -1 62410 21230 2 1406.7831 704.3978 Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1 6 3859.8 - 155155 - - - 1.5262 - 1.404 0.28 - 201.3 1 2 0 0.0021 13 0 0 0 0.00E+00 0.00E+00 - - - 1.9793 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.21232.21232.2 0.0106 22-Aug R.LTSLGVIGALVK[136.11].T sp|Q92600|CNOT9_HUMAN 1 1177.7526 -1 62412 21232 2 1177.754569 589.8836 CCR4-NOT transcription complex subunit 9 OS=Homo sapiens OX=9606 GN=CNOT9 PE=1 SV=1 8.75 3860.1 - 0 - - - 1.7058 - 1.497 0.35 - 87.1 1 2 0 0.002 12 0 0 0 0.00E+00 0.00E+00 - - - 2.687 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.21236.21236.2 0.0252 20-Jul K.DFPLSGYVELR[166.11].Y sp|O75489|NDUS3_HUMAN 1 1304.664 2.71 62415 21236 2 1304.666215 653.3393 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 4.37 3860.7 - 581740 - - - 1.6809 - 1.259 0.345 - 102.5 1 2 0 0.0022 11 0 0 0 6.51E+06 2.40E+06 - - - 2.2115 1 230117_WJC_METTL3_WT_vs_EV_F07.21237.21237.2 3.33E-07 14/26 K.LFIYNPTTGEFLGR.T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1626.8406 1.51 62416 21237 2 1626.840299 814.4276 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3860.8 - 2.75E+06 - - - -0.1807 - 2.684 0.556 - 580.2 1 2 0 -0.0003 14 0 0 0 3.18E+07 2.10E+07 - - - 5.6251 1 230117_WJC_METTL3_WT_vs_EV_F07.21238.21238.2 4.60E-06 13/22 R.LEGLTDEINFLR.Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1418.7405 1.7 62417 21238 2 1418.741718 710.3775 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3860.9 - 2.41E+06 - - - 0.8268 - 2.635 0.538 - 679.4 1 2 0 0.0012 12 0 0 0 2.50E+07 1.47E+07 - - - 5.5636 1 230117_WJC_METTL3_WT_vs_EV_F07.21239.21239.2 1.23E-05 14/26 K.LFIYNPTTGEFLGR[166.11].T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1636.8489 1.51 62418 21239 2 1636.84906 819.4317 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3861 - 2.35E+06 - - - 0.1204 - 2.203 0.553 - 544.6 1 2 0 0.0002 14 0 0 0 3.18E+07 2.10E+07 - - - 5.1074 1 230117_WJC_METTL3_WT_vs_EV_F07.21241.21241.3 2.79E-08 20/56 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 6.5 62420 21241 3 1700.901381 567.9734 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3861.2 - 1.64E+06 - - - 1.6926 - 3.47 0.618 - 677.3 1 2 0 0.0029 15 0 0 0 7.26E+07 1.12E+07 - - - 8.6757 1 230117_WJC_METTL3_WT_vs_EV_F07.21243.21243.2 0.000958 18-Nov K.FSLFAGGMLR.V sp|Q9BVK6|TMED9_HUMAN 1 1097.5692 1.36 62422 21243 2 1097.569603 549.7919 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 9.75 3861.5 - 1.23E+06 - - - 0.3799 - 2.222 0.462 - 465.5 1 2 0 0.0004 10 0 0 0 7.94E+06 5.83E+06 - - - 4.6818 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.21244.21244.2 0.0268 14-Jun R.EGLLAIFK[136.11].S "sp|P35222|CTNB1_HUMAN,sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|C9J826|C9J826_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 15 897.5415 6.72 62423 21244 2 897.541584 449.778 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 6.1 3861.6 - 1.03E+06 - - - 0.0891 - 1.475 0.315 - 109.2 1 2 0 0.0001 8 0 0 0 2.09E+07 3.11E+06 - - - 2.5397 0.8921 230117_WJC_METTL3_WT_vs_EV_F07.21245.21245.2 0.0629 12-Jun Y.SSFLFWR.M sp|Q13015|AF1Q_HUMAN 1 941.4759 2.84 62424 21245 2 941.476462 471.7452 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 9.47 3861.8 - 1.00E+06 - - - 0.5566 - 1.463 0.251 - 153.1 1 1 0 0.0005 7 0 0 0 3.19E+06 1.12E+06 - - - 2.1003 1 230117_WJC_METTL3_WT_vs_EV_F07.21246.21246.2 2.07E-05 14/26 R.VLLATLSIPITPER.T sp|Q14152|EIF3A_HUMAN 1 1521.913 0.96 62425 21246 2 1521.914825 761.9638 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3861.9 - 959213 - - - 1.1794 - 2.794 0.497 - 599.4 1 2 0 0.0018 14 0 0 0 4.28E+07 4.47E+07 - - - 5.2897 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21247.21247.3 0.279 Dec-44 R.LLALLDALASHK.A "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 1263.7551 1.74 62426 21247 3 1263.754603 422.259 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 6.74 3862 - 944570 - - - -0.3719 - 2.751 0.273 - 275.7 1 2 0 -0.0005 12 0 0 0 3.60E+06 2.07E+06 - - - 4.3886 0.9938 230117_WJC_METTL3_WT_vs_EV_F07.21251.21251.2 0.0113 18-Sep R.LPLVVEDFVK.D "sp|Q8NB37|GALD1_HUMAN,tr|H0YF25|H0YF25_HUMAN,tr|H0YE25|H0YE25_HUMAN,tr|H0YER3|H0YER3_HUMAN" 4 1157.6696 3.43 62430 21251 2 1157.664896 579.8421 Glutamine amidotransferase-like class 1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GATD1 PE=1 SV=1 4.37 3862.5 - 445588 - - - -4.0737 - 1.92 0.414 - 216 1 2 0 -0.0047 10 0 0 0 2.36E+06 6.88E+05 - - - 3.9182 1 230117_WJC_METTL3_WT_vs_EV_F07.21254.21254.2 7.73E-06 24-Nov R.APLPDLYPFGTMR.G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1476.7435 1.71 62433 21254 2 1476.747681 739.379 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3862.9 - 343842 - - - 2.8163 - 2.169 0.511 - 422.7 1 2 0 0.0042 13 0 0 0 1.20E+07 7.01E+06 - - - 4.8011 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21256.21256.2 1.10E-05 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 62434 21256 2 1603.765568 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3863.2 - 1.81E+08 - - - 1.0151 - 1.905 0.511 - 223.5 1 2 0 0.0016 12 0 0 0 2.53E+09 0.00E+00 - - - 4.5105 0.999 230117_WJC_METTL3_WT_vs_EV_F07.21258.21258.2 1.87E-05 20-Dec R.GVTFLFPIQAK.T sp|Q9NR30|DDX21_HUMAN 1 1219.6965 0.96 62436 21258 2 1219.695664 610.8555 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3863.3 - 6.91E+06 - - - -0.6813 - 2.27 0.281 - 555.8 1 2 0 -0.0008 11 0 0 0 1.17E+08 1.21E+08 - - - 3.3339 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.21259.21259.2 1.59E-05 20-Oct K.SGAYLIPLLER[166.11].L "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1240.7055 1.19 62437 21259 2 1240.705417 621.36 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.72 3863.4 - 4.06E+06 - - - -0.0613 - 1.953 0.299 - 324.6 1 2 0 -0.0001 11 0 0 0 2.15E+08 1.80E+08 - - - 3.0602 1 230117_WJC_METTL3_WT_vs_EV_F07.21260.21260.2 7.63E-11 14/26 K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 15.01 62438 21260 2 1621.815917 811.9149 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3863.4 - 3.63E+06 - - - 0.3829 - 2.509 0.571 - 450.3 1 2 0 0.0006 14 0 0 0 1.11E+09 7.38E+07 - - - 5.5666 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.21261.21261.2 0.00014 14-Sep R.FPLFGGWK.T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 950.5014 1.5 62439 21261 2 950.500683 476.258 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3863.5 - 2.77E+06 - - - -0.7796 - 1.761 0.386 - 313.8 1 2 0 -0.0007 8 0 0 0 4.09E+07 2.72E+07 - - - 3.5984 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.21262.21262.2 0.00066 14-Aug K.FYSFLVLK.K "sp|Q9H4I0|RD21L_HUMAN,sp|O60216|RAD21_HUMAN,tr|A0A804HJ87|A0A804HJ87_HUMAN,tr|E5RI01|E5RI01_HUMAN,tr|E5RG18|E5RG18_HUMAN,tr|E5RFZ5|E5RFZ5_HUMAN" 6 1015.5743 3.79 62440 21262 2 1015.574144 508.7944 Double-strand-break repair protein rad21-like protein 1 OS=Homo sapiens OX=9606 GN=RAD21L1 PE=2 SV=3 8.59 3863.6 - 2.66E+06 - - - -0.1093 - 1.568 0.406 - 159.1 1 2 0 -0.0001 8 0 0 0 2.96E+07 7.82E+06 - - - 3.3963 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21263.21263.2 0.00105 18-Oct K.FEELNMDLFR.S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1312.6122 3.6 62441 21263 2 1312.611744 657.3134 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.14 3863.6 - 2.38E+06 - - - -0.3268 - 2.187 0.409 - 368 1 2 0 -0.0004 10 0 0 0 4.36E+07 1.21E+07 - - - 4.246 1 230117_WJC_METTL3_WT_vs_EV_F07.21264.21264.2 3.18E-07 14/22 R.LEGLTDEINFLR[166.11].Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1428.7488 1.7 62442 21264 2 1428.74732 715.3817 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3863.7 - 2.03E+06 - - - -1.0464 - 2.831 0.551 - 881.8 1 2 0 -0.0015 12 0 0 0 2.50E+07 1.47E+07 - - - 5.8483 0.9924 230117_WJC_METTL3_WT_vs_EV_F07.21270.21270.2 0.191 14-Jun R.SFTNQIIL.- "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIM4|A0A804HIM4_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 3 934.5124 - 62448 21270 2 934.511442 468.2635 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 5.24 3864.4 - 498058 - - - -1.0069 - 1.216 0.244 - 63.4 1 2 0 -0.0009 8 0 0 0 - - - - - 1.4327 1 230117_WJC_METTL3_WT_vs_EV_F07.21277.21277.3 1.07E-06 13/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 62454 21277 3 1603.763392 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3865.3 - 7.45E+06 - - - -0.3417 - 2.365 0.607 - 258.2 1 2 0 -0.0005 12 0 0 0 2.00E+08 0.00E+00 - - - 7.6932 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.21278.21278.2 0.00609 20-Jul R.GVTFLFPIQAK[136.11].T sp|Q9NR30|DDX21_HUMAN 1 1227.7107 0.97 62455 21278 2 1227.710086 614.8626 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3865.3 - 2.83E+07 - - - -0.496 - 1.464 0.304 - 201.9 1 2 0 -0.0006 11 0 0 0 1.17E+08 1.21E+08 - - - 2.3173 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21280.21280.2 0.000131 16-Sep R.IIFVDEVFK.L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1108.6168 2.82 62457 21280 2 1108.617104 555.3157 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 4.37 3865.4 - 8.89E+06 - - - 0.2309 - 1.925 0.489 - 199.2 1 2 0 0.0003 9 0 0 0 4.52E+07 1.60E+07 - - - 4.5474 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.21281.21281.2 3.79E-05 16-Aug R.IIFVDEVFK[136.11].L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1116.631 2.77 62458 21281 2 1116.630172 559.3228 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 4.37 3865.5 - 6.36E+06 - - - -0.7845 - 1.602 0.531 - 162.4 1 2 0 -0.0009 9 0 0 0 4.44E+07 1.60E+07 - - - 4.3261 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.21283.21283.3 1.89E-08 16/52 K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 14.82 62460 21283 3 1621.814555 541.6124 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3865.6 - 2.87E+06 - - - -0.4569 - 2.652 0.555 - 312.3 1 2 0 -0.0007 14 0 0 0 2.92E+08 1.97E+07 - - - 7.3194 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.21284.21284.2 0.000886 14-Aug R.GFVFITFK[136.11].E "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 965.5466 0.75 62461 21284 2 965.545837 483.7806 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3865.7 - 2.81E+06 - - - -0.7799 - 1.612 0.438 - 281.7 1 2 0 -0.0008 8 0 0 0 2.18E+07 2.93E+07 - - - 3.7159 1 230117_WJC_METTL3_WT_vs_EV_F07.21287.21287.2 7.00E-05 14/26 R.DYGVLLEGSGLALR[166.11].G sp|P30048|PRDX3_HUMAN 1 1471.791 1.2 62464 21287 2 1471.789644 736.9028 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 4.37 3866 - 1.49E+06 - - - -0.9308 - 2.586 0.526 - 619 1 2 0 -0.0014 14 0 0 0 1.27E+07 1.06E+07 - - - 5.3099 1 230117_WJC_METTL3_WT_vs_EV_F07.21290.21290.2 0.000205 26-Dec R.ILGIPVIVTEQYPK.G "sp|Q96CN7|ISOC1_HUMAN,tr|D6RGE2|D6RGE2_HUMAN" 2 1568.9178 1.35 62467 21290 2 1568.919946 785.4662 Isochorismatase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ISOC1 PE=1 SV=3 6 3866.4 - 1.13E+06 - - - 1.3799 - 2.374 0.506 - 383.9 1 2 0 0.0022 14 0 0 0 4.42E+06 3.28E+06 - - - 4.9472 1 230117_WJC_METTL3_WT_vs_EV_F07.21292.21292.2 0.000107 24-Dec R.APLPDLYPFGTMR[166.11].G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1486.7518 1.76 62469 21292 2 1486.753845 744.3832 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3866.7 - 1.09E+06 - - - 1.3809 - 2.178 0.486 - 442.3 1 2 0 0.0021 13 0 0 0 1.17E+07 6.66E+06 - - - 4.6278 0.9751 230117_WJC_METTL3_WT_vs_EV_F07.21296.21296.2 0.00354 14-Aug R.FPLFGGWK[136.11].T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 958.5156 1.5 62471 21296 2 958.510649 480.2651 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3867.2 - 462087 - - - -5.1903 - 1.403 0.376 - 192.3 1 2 0 -0.005 8 0 0 0 4.09E+07 2.72E+07 - - - 2.8378 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.21299.21299.2 0.00271 18-Oct K.FEELNMDLFR[166.11].S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1322.6204 3.6 62474 21299 2 1322.618405 662.3175 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.14 3867.6 - 0 - - - -1.5409 - 2.111 0.359 - 325.4 1 2 0 -0.002 10 0 0 0 4.36E+07 1.21E+07 - - - 3.7775 0.9771 230117_WJC_METTL3_WT_vs_EV_F07.21302.21302.3 0.266 Dec-52 R.VLLATLSIPITPER[166.11].T sp|Q14152|EIF3A_HUMAN 1 1531.9213 0.94 62477 21302 3 1531.920599 511.6477 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3867.9 - 49448.5 - - - -0.4576 - 1.643 0.133 - 130.9 1 2 0 -0.0007 14 0 0 0 4.66E+06 4.98E+06 - - - 1.3422 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.21304.21304.2 0.000842 20-Nov K.NVPGLAILLSK.D sp|Q9BUL9|RPP25_HUMAN 1 1123.6965 1.56 62479 21304 2 1123.696538 562.8555 Ribonuclease P protein subunit p25 OS=Homo sapiens OX=9606 GN=RPP25 PE=1 SV=1 8.75 3868.1 - 0 - - - 0.0383 - 1.739 0.41 - 300.8 1 2 0 0 11 0 0 0 8.08E+06 5.19E+06 - - - 3.5661 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21305.21305.2 0.000113 26-Sep R.ILGIPVIVTEQYPK[136.11].G "sp|Q96CN7|ISOC1_HUMAN,tr|D6RGE2|D6RGE2_HUMAN" 2 1576.932 1.35 62480 21305 2 1576.935001 789.4733 Isochorismatase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ISOC1 PE=1 SV=3 6 3868.3 - 0 - - - 1.9151 - 1.769 0.478 - 166.7 1 2 0 0.003 14 0 0 0 4.42E+06 3.28E+06 - - - 4.002 1 230117_WJC_METTL3_WT_vs_EV_F07.21309.21309.2 6.69E-07 16/26 R.VLLATLSIPITPER[166.11].T sp|Q14152|EIF3A_HUMAN 1 1531.9213 0.96 62482 21309 2 1531.922219 766.9679 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3868.8 - 2.97E+06 - - - 0.5999 - 3.047 0.543 - 739 1 2 0 0.0009 14 0 0 0 4.28E+07 4.47E+07 - - - 5.8472 1 230117_WJC_METTL3_WT_vs_EV_F07.21310.21310.2 0.00103 14/20 K.LSDLDYMQFIR.L sp|P82933|RT09_HUMAN 1 1399.6806 1.08 62483 21310 2 1399.680741 700.8476 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.21 3868.9 - 1.14E+06 - - - 0.11 - 2.985 0.417 - 1204.1 1 2 0 0.0002 11 0 0 0 9.31E+06 8.64E+06 - - - 5.0794 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21313.21313.2 0.00412 16-Sep K.TTPLLSFLK[136.11].N sp|Q9BZI7|REN3B_HUMAN 1 1026.6205 0.92 62486 21313 2 1026.62061 514.3175 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 8.41 3869.3 - 1.36E+06 - - - 0.1237 - 1.781 0.402 - 343.4 1 2 0 0.0001 9 0 0 0 1.59E+07 1.73E+07 - - - 3.6799 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.21315.21315.2 0.00228 20-Nov K.LSDLDYMQFIR[166.11].L sp|P82933|RT09_HUMAN 1 1409.6889 1.08 62488 21315 2 1409.688113 705.8517 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.21 3869.6 - 1.17E+06 - - - -0.5278 - 2.538 0.343 - 617.6 1 2 0 -0.0007 11 0 0 0 9.31E+06 8.64E+06 - - - 4.0938 1 230117_WJC_METTL3_WT_vs_EV_F07.21318.21318.2 3.85E-08 16/26 R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 16.47 62491 21318 2 1581.80827 791.9109 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3870 - 742104 - - - 0.6486 - 3.166 0.656 - 705.1 1 2 0 0.001 14 0 0 0 1.97E+07 1.19E+06 - - - 6.778 0.9135 230117_WJC_METTL3_WT_vs_EV_F07.21320.21320.2 0.525 20-Jul K.AIGFVMVDAKK.E sp|O14958|CASQ2_HUMAN 1 1177.6529 1.66 62493 21320 2 1177.649775 589.8337 Calsequestrin-2 OS=Homo sapiens OX=9606 GN=CASQ2 PE=1 SV=2 8.64 3870.2 - 500694 - - - -2.6672 - 1.409 0.07 - 107.1 2 2 0 -0.0031 11 0 0 0 4.15E+06 2.51E+06 - - - 0.3501 0.9967 230117_WJC_METTL3_WT_vs_EV_F07.21321.21321.2 7.43E-05 18-Sep K.C[160.03]PFLIPFETR.Q "sp|Q9ULT8|HECD1_HUMAN,tr|H0YJD4|H0YJD4_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN" 3 1278.6431 1.24 62494 21321 2 1278.639119 640.3288 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 5.99 3870.4 - 394408 - - - -3.0978 - 1.966 0.414 - 367.9 1 2 0 -0.004 10 0 0 0 3.08E+06 2.48E+06 - - - 3.9845 0.971 230117_WJC_METTL3_WT_vs_EV_F07.21325.21325.2 0.0556 20-Aug K.IALGIPLPEIK.N "sp|P31327|CPSM_HUMAN,tr|A0A669KBF2|A0A669KBF2_HUMAN" 2 1162.7325 2.64 62498 21325 2 1162.730273 582.3735 "Carbamoyl-phosphate synthase [ammonia], mitochondrial OS=Homo sapiens OX=9606 GN=CPS1 PE=1 SV=2" 6 3870.9 - 245563 - - - -1.9549 - 1.53 0.089 - 121.1 1 2 0 -0.0023 11 0 0 0 3.02E+06 1.14E+06 - - - 0.8481 1 230117_WJC_METTL3_WT_vs_EV_F07.21330.21330.2 1.65E-08 22-Nov K.VDALMDEINFMK.M "sp|P13647|K2C5_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 2 1424.668 342.63 62500 21330 2 1424.668786 713.3413 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.03 3871.4 - 8.26E+06 - - - 0.5707 - 2.614 0.65 - 427.2 1 2 0 0.0008 12 0 0 0 2.11E+07 6.15E+04 - - - 6.3699 1 230117_WJC_METTL3_WT_vs_EV_F07.21331.21331.2 3.67E-07 24-Dec R.ELPTAFDYVEFTR[166.11].S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1596.7699 0.98 62501 21331 2 1596.771632 799.3922 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.14 3871.5 - 3.89E+06 - - - 1.0571 - 2.52 0.643 - 687.6 1 2 0 0.0017 13 0 0 0 9.71E+06 9.91E+06 - - - 6.1618 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.21334.21334.2 0.000454 16-Aug K.AFVPAILFK[136.11].D sp|Q9HAU5|RENT2_HUMAN 1 1012.6201 -1 62504 21334 2 1012.619737 507.3173 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3871.6 - 2.44E+06 - - - -0.3476 - 1.636 0.479 - 224.2 1 2 0 -0.0004 9 0 0 0 0.00E+00 0.00E+00 - - - 4.0029 1 230117_WJC_METTL3_WT_vs_EV_F07.21335.21335.2 1.69E-06 24-Nov R.ELYAFFGDSLATR.F sp|Q9Y6J9|TAF6L_HUMAN 1 1488.7249 -1 62505 21335 2 1488.720596 745.3697 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4.37 3871.7 - 2.42E+06 - - - -2.8877 - 2.055 0.594 - 403.1 1 2 0 -0.0043 13 0 0 0 0.00E+00 0.00E+00 - - - 5.2755 1 230117_WJC_METTL3_WT_vs_EV_F07.21336.21336.2 2.87E-05 22-Nov K.LTAYAMTIPFVR.Q "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1381.7428 1.29 62506 21336 2 1381.743552 691.8787 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 3871.7 - 2.38E+06 - - - 0.5493 - 2.411 0.529 - 567.9 1 2 0 0.0008 12 0 0 0 5.10E+06 3.94E+06 - - - 5.2635 1 230117_WJC_METTL3_WT_vs_EV_F07.21337.21337.2 1.48E-05 26-Oct R.ILSVQGTEPLVLFK.E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1542.9021 -1 62507 21337 2 1542.904214 772.4583 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3871.8 - 2.29E+06 - - - 1.3501 - 2.041 0.516 - 282 1 2 0 0.0021 14 0 0 0 0.00E+00 0.00E+00 - - - 4.6419 0.9998 230117_WJC_METTL3_WT_vs_EV_F07.21338.21338.3 0.00075 Aug-52 R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 8.91 62508 21338 3 1581.807619 528.2764 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3871.8 - 2.05E+06 - - - 0.2371 - 1.86 0.401 - 113.9 1 2 0 0.0004 14 0 0 0 3.98E+06 4.47E+05 - - - 4.6599 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21340.21340.2 0.000865 16-Aug K.AFVPAILFK.D sp|Q9HAU5|RENT2_HUMAN 1 1004.6059 -1 62510 21340 2 1004.605698 503.3102 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3871.9 - 1.89E+06 - - - -0.1901 - 1.834 0.425 - 262 1 2 0 -0.0002 9 0 0 0 0.00E+00 0.00E+00 - - - 3.9346 1 230117_WJC_METTL3_WT_vs_EV_F07.21341.21341.2 4.44E-06 26-Oct R.ILSVQGTEPLVLFK[136.11].E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1550.9163 -1 62511 21341 2 1550.91721 776.4654 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3872 - 1.89E+06 - - - 0.5668 - 2.226 0.531 - 316.7 1 2 0 0.0009 14 0 0 0 0.00E+00 0.00E+00 - - - 4.9708 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21342.21342.2 8.58E-06 22-Aug K.LTAYAMTIPFVR[166.11].Q "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1391.7511 1.29 62512 21342 2 1391.752218 696.8828 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 3872 - 1.83E+06 - - - 0.8299 - 1.827 0.513 - 280.9 1 2 0 0.0012 12 0 0 0 5.10E+06 3.94E+06 - - - 4.4154 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21344.21344.2 0.000618 18-Sep R.LLEVYDQLFK.S "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1266.686 2.11 62514 21344 2 1266.686142 634.3503 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3872.1 - 1.36E+06 - - - 0.12 - 1.987 0.467 - 260.4 1 2 0 0.0002 10 0 0 0 7.14E+06 3.38E+06 - - - 4.4068 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.21345.21345.2 0.0109 20-Aug R.SIFTGLMIDPR.T sp|Q8IWA0|WDR75_HUMAN 1 1248.6536 1.6 62515 21345 2 1248.656063 625.3341 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 5.55 3872.2 - 1.33E+06 - - - 1.9373 - 1.446 0.224 - 162.3 1 2 0 0.0024 11 0 0 0 4.34E+06 2.72E+06 - - - 1.6924 1 230117_WJC_METTL3_WT_vs_EV_F07.21346.21346.2 3.10E-06 14/26 K.TGAAGAEALSLLLK.R "sp|Q9P2N6|KANL3_HUMAN,tr|C9J5A4|C9J5A4_HUMAN,tr|A0A590UJ53|A0A590UJ53_HUMAN" 3 1313.7555 5.86 62516 21346 2 1313.757071 657.885 KAT8 regulatory NSL complex subunit 3 OS=Homo sapiens OX=9606 GN=KANSL3 PE=1 SV=2 5.66 3872.2 - 1.20E+06 - - - 1.2209 - 2.634 0.469 - 662.1 1 2 0 0.0016 14 0 0 0 3.67E+06 6.26E+05 - - - 4.9349 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.21350.21350.3 7.29E-05 Dec-40 R.SIIGMIDMFHK.Y "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1290.6464 57.14 62519 21350 3 1290.646421 431.2228 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.46 3872.7 - 163582 - - - -0.0225 - 2.07 0.504 - 156 1 2 0 0 11 0 0 0 3.66E+06 6.41E+04 - - - 6.2259 1 230117_WJC_METTL3_WT_vs_EV_F07.21354.21354.2 1.10E-10 15/24 R.ELPTAFDYVEFTR.S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1586.7617 0.98 62523 21354 2 1586.764747 794.3881 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.14 3873.1 - 468270 - - - 1.9366 - 2.728 0.601 - 956.7 1 2 0 0.0031 13 0 0 0 9.71E+06 9.91E+06 - - - 6.0547 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.21358.21358.2 0.0325 14-Jul R.LQWWDFTK.F "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1122.5498 0.56 62527 21358 2 1122.551751 562.2822 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 5.84 3873.7 - 229043 - - - 1.7104 - 1.374 0.286 - 149.6 1 2 0 0.0019 8 0 0 0 1.45E+06 2.60E+06 - - - 2.111 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.21360.21360.2 0.125 14-Jul R.LQWWDFTK[136.11].F "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1130.564 -1 62529 21360 2 1130.566196 566.2893 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 5.84 3873.9 - 157773 - - - 1.915 - 1.258 0.224 - 136 1 2 0 0.0022 8 0 0 0 0.00E+00 0.00E+00 - - - 1.387 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.21361.21361.2 1.37E-05 20-Oct R.WPDPEDLLTPR[166.11].W sp|Q8TAE8|G45IP_HUMAN 1 1347.6698 1.48 62530 21361 2 1347.668617 674.8422 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.03 3874 - 155344 - - - -0.9045 - 1.912 0.267 - 280.5 1 2 0 -0.0012 11 0 0 0 1.32E+07 8.91E+06 - - - 2.7661 1 230117_WJC_METTL3_WT_vs_EV_F07.21363.21363.2 1.72E-06 13/22 R.LIMNYLVTEGFK[136.11].E sp|Q9NWU2|GID8_HUMAN 1 1434.7672 1.37 62532 21363 2 1434.770945 718.3909 Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1 6 3874.3 - 126337 - - - 2.5935 - 2.301 0.606 - 422.8 1 2 0 0.0037 12 0 0 0 9.02E+06 6.59E+06 - - - 5.7084 1 230117_WJC_METTL3_WT_vs_EV_F07.21364.21364.2 8.80E-06 20/26 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.45 62533 21364 2 1672.88377 837.4479 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3874.4 - 114065 - - - 1.5207 - 3.585 0.597 - 1785.2 1 2 0 0.0025 14 0 0 0 7.38E+07 1.65E+08 - - - 6.6536 0.9928 230117_WJC_METTL3_WT_vs_EV_F07.21365.21365.2 0.0207 18-Aug K.DALLLWC[160.03]QMK[136.11].T "sp|P11277|SPTB1_HUMAN,sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,sp|Q9H254|SPTN4_HUMAN,tr|C9JY79|C9JY79_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|M0QZQ3|M0QZQ3_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 9 1284.645 1.82 62534 21365 2 1284.648267 643.3298 "Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB PE=1 SV=5" 5.83 3874.6 - 111200 - - - 2.5431 - 1.512 0.103 - 155.2 1 2 0 0.0033 10 0 0 0 3.21E+06 1.76E+06 - - - 0.9548 1 230117_WJC_METTL3_WT_vs_EV_F07.21372.21372.2 5.54E-08 19/26 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.45 62540 21372 2 1662.873961 832.4438 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3875.4 - 1.73E+06 - - - 0.6044 - 3.399 0.596 - 1682 1 2 0 0.001 14 0 0 0 7.38E+07 1.65E+08 - - - 6.513 1 230117_WJC_METTL3_WT_vs_EV_F07.21373.21373.3 1.70E-09 19/52 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.56 62541 21373 3 1672.882729 558.6344 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3875.4 - 1.24E+06 - - - 0.8984 - 3.489 0.573 - 711.6 1 2 0 0.0015 14 0 0 0 3.29E+07 5.88E+07 - - - 8.2489 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21376.21376.2 0.00188 18-Oct R.LLEVYDQLFK[136.11].S "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1274.7002 2.32 62544 21376 2 1274.702728 638.3574 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3875.7 - 281006 - - - 1.9911 - 1.993 0.402 - 328.6 1 2 0 0.0025 10 0 0 0 4.87E+06 2.10E+06 - - - 3.9344 1 230117_WJC_METTL3_WT_vs_EV_F07.21382.21382.2 3.04E-10 16/30 R.LFVGNLPADITEDEFK[136.11].R sp|P23246|SFPQ_HUMAN 1 1814.9182 -1 62550 21382 2 1814.915054 908.4664 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3876.4 - 144368 - - - -1.7229 - 3.277 0.572 - 539.9 1 2 0 -0.0031 16 0 0 0 0.00E+00 0.00E+00 - - - 6.1829 1 230117_WJC_METTL3_WT_vs_EV_F07.21389.21389.3 7.95E-06 14/52 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.56 62556 21389 3 1662.875281 555.2983 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3877.3 - 1.44E+07 - - - 1.3982 - 2.894 0.522 - 306.8 1 2 0 0.0023 14 0 0 0 3.30E+07 5.88E+07 - - - 7.1831 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21390.21390.2 0.00193 22-Dec R.GLFIIDPNGVIK.H sp|P30048|PRDX3_HUMAN 1 1284.7442 2 62557 21390 2 1284.744721 643.3794 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3877.4 - 8.61E+06 - - - 0.4258 - 2.157 0.39 - 370.8 1 2 0 0.0005 12 0 0 0 6.31E+07 3.15E+07 - - - 3.944 1 230117_WJC_METTL3_WT_vs_EV_F07.21392.21392.2 1.57E-10 13/24 R.FGQDIISPLLSVK[136.11].E "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V414|A0A7I2V414_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|J3KNG4|J3KNG4_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|G3V5F3|G3V5F3_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|A0A7I2V4B9|A0A7I2V4B9_HUMAN,tr|H0YJY1|H0YJY1_HUMAN,tr|H0YJS6|H0YJS6_HUMAN,tr|G3V363|G3V363_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2V5R9|A0A7I2V5R9_HUMAN,tr|G3V4I1|G3V4I1_HUMAN,tr|A0A7I2V3Y3|A0A7I2V3Y3_HUMAN" 24 1423.8166 1.62 62559 21392 2 1423.817676 712.9156 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 5.84 3877.5 - 6.54E+06 - - - 0.7438 - 2.83 0.658 - 639.1 1 2 0 0.0011 13 0 0 0 2.02E+07 1.24E+07 - - - 6.5706 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21394.21394.2 0.00102 22-Dec R.GLFIIDPNGVIK[136.11].H sp|P30048|PRDX3_HUMAN 1 1292.7584 2 62561 21394 2 1292.759481 647.3865 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3877.6 - 4.83E+06 - - - 0.8563 - 2.21 0.336 - 358.2 1 2 0 0.0011 12 0 0 0 6.31E+07 3.15E+07 - - - 3.6088 1 230117_WJC_METTL3_WT_vs_EV_F07.21395.21395.2 1.11E-07 13/20 K.TITAYFGDLIR[166.11].R sp|Q96RS0|TGS1_HUMAN 1 1278.6848 1.4 62562 21395 2 1278.685575 640.3497 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 5.5 3877.7 - 3.50E+06 - - - 0.6389 - 2.293 0.608 - 495 1 2 0 0.0008 11 0 0 0 9.88E+06 7.08E+06 - - - 5.7764 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.21396.21396.2 0.000221 18-Sep K.DAITQALFLR.E sp|Q9UNX4|WDR3_HUMAN 1 1146.6397 1.11 62563 21396 2 1146.638581 574.3271 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.84 3877.8 - 3.48E+06 - - - -0.9829 - 2.008 0.427 - 266.4 1 2 0 -0.0011 10 0 0 0 2.97E+07 2.68E+07 - - - 4.1404 1 230117_WJC_METTL3_WT_vs_EV_F07.21397.21397.2 5.77E-13 16/28 R.FYAYNPLAGGLLTGK.Y "sp|Q8NHP1|ARK74_HUMAN,sp|O43488|ARK72_HUMAN,tr|A0A499FJT0|A0A499FJT0_HUMAN,tr|H3BLU7|H3BLU7_HUMAN" 4 1583.8348 1.47 62564 21397 2 1583.837768 792.9247 Aflatoxin B1 aldehyde reductase member 4 OS=Homo sapiens OX=9606 GN=AKR7L PE=2 SV=7 8.5 3877.8 - 3.14E+06 - - - 1.8866 - 3.111 0.724 - 829.9 1 2 0 0.003 15 0 0 0 6.72E+06 4.57E+06 - - - 7.1778 1 230117_WJC_METTL3_WT_vs_EV_F07.21399.21399.2 0.000108 14/24 K.DAAIYLVTSLASK.A sp|P55060|XPO2_HUMAN 1 1350.7395 -1 62566 21399 2 1350.743178 676.377 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.83 3878.1 - 1.71E+06 - - - 2.7363 - 2.719 0.511 - 681.5 1 2 0 0.0037 13 0 0 0 0.00E+00 0.00E+00 - - - 5.3813 0.999 230117_WJC_METTL3_WT_vs_EV_F07.21400.21400.2 0.00187 18-Aug R.AEVWDLDMLR.S sp|Q6P2E9|EDC4_HUMAN 1 1246.6016 1.19 62567 21400 2 1246.601383 624.3081 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 4.03 3878.2 - 1.44E+06 - - - -0.1805 - 1.47 0.391 - 255.2 1 2 0 -0.0002 10 0 0 0 1.87E+06 1.57E+06 - - - 3.0042 1 230117_WJC_METTL3_WT_vs_EV_F07.21403.21403.2 2.02E-08 13/32 R.LWVGGLGPNTSLAALAR[166.11].E sp|Q8NDT2|RB15B_HUMAN 1 1704.9551 -1 62570 21403 2 1704.955459 853.4848 Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3 9.75 3878.6 - 1.19E+06 - - - 0.234 - 2.608 0.588 - 415 1 2 0 0.0004 17 0 0 0 0.00E+00 0.00E+00 - - - 5.7406 1 230117_WJC_METTL3_WT_vs_EV_F07.21404.21404.2 3.07E-05 Nov-32 R.LWVGGLGPNTSLAALAR.E sp|Q8NDT2|RB15B_HUMAN 1 1694.9468 0.81 62571 21404 2 1694.947598 848.4807 Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3 9.75 3878.7 - 1.12E+06 - - - 0.4767 - 2.512 0.46 - 218.7 1 2 0 0.0008 17 0 0 0 1.74E+06 2.15E+06 - - - 4.7028 1 230117_WJC_METTL3_WT_vs_EV_F07.21411.21411.2 1.24E-05 14/24 K.NVLIVEDIIDTGK.T sp|P00492|HPRT_HUMAN 1 1427.7872 1.94 62577 21411 2 1427.788901 714.9009 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.03 3879.5 - 1.01E+06 - - - 1.2187 - 2.727 0.547 - 593.8 1 2 0 0.0017 13 0 0 0 7.65E+06 3.95E+06 - - - 5.6553 1 230117_WJC_METTL3_WT_vs_EV_F07.21412.21412.2 9.43E-06 15/24 K.NVLIVEDIIDTGK[136.11].T sp|P00492|HPRT_HUMAN 1 1435.8014 1.99 62578 21412 2 1435.80696 718.908 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.03 3879.7 - 521469 - - - 3.8996 - 2.796 0.506 - 717.3 1 2 0 0.0056 13 0 0 0 7.65E+06 3.85E+06 - - - 5.4154 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.21415.21415.2 0.00185 20-Oct R.LTGLLDLALEK.D sp|P04746|AMYP_HUMAN 1 1184.7016 0.99 62581 21415 2 1184.705678 593.3581 Pancreatic alpha-amylase OS=Homo sapiens OX=9606 GN=AMY2A PE=1 SV=2 4.37 3880 - 379171 - - - 3.4085 - 2.277 0.381 - 211.3 1 2 0 0.004 11 0 0 0 3.09E+06 3.12E+06 - - - 4.0798 0.9768 230117_WJC_METTL3_WT_vs_EV_F07.21416.21416.2 0.000108 22-Oct S.ILTIEDGIFEVK.S "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1375.7599 12.33 62582 21416 2 1375.762208 688.8872 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3880.2 - 347614 - - - 1.69 - 2.158 0.423 - 338.5 1 1 0 0.0023 12 0 0 0 3.43E+06 2.78E+05 - - - 4.1884 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.21417.21417.2 0.00357 18-Sep K.VFFNILEEAR[166.11].E "sp|Q9Y276|BCS1_HUMAN,tr|C9J1S9|C9J1S9_HUMAN,tr|C9J8G3|C9J8G3_HUMAN" 3 1246.6585 0.4 62583 21417 2 1246.657798 624.3365 Mitochondrial chaperone BCS1 OS=Homo sapiens OX=9606 GN=BCS1L PE=1 SV=1 4.53 3880.3 - 330544 - - - -0.5976 - 1.502 0.384 - 239.3 1 2 0 -0.0007 10 0 0 0 1.38E+06 3.46E+06 - - - 3.0125 0.987 230117_WJC_METTL3_WT_vs_EV_F07.21420.21420.2 5.04E-05 22-Dec K.SLPVSVPVWGFK[136.11].E sp|Q96B36|AKTS1_HUMAN 1 1322.7478 2.78 62586 21420 2 1322.757223 662.3812 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 8.47 3880.7 - 306923 - - - 7.117 - 2.077 0.318 - 445.4 1 2 0 0.0094 12 0 0 0 1.01E+07 3.66E+06 - - - 3.31 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.21423.21423.3 6.63E-06 Nov-48 K.DAAIYLVTSLASK[136.11].A sp|P55060|XPO2_HUMAN 1 1358.7537 5.5 62589 21423 3 1358.756638 453.9252 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.83 3881.1 - 131070 - - - 2.1755 - 2.597 0.388 - 243.7 1 2 0 0.003 13 0 0 0 7.85E+06 1.43E+06 - - - 5.4525 1 230117_WJC_METTL3_WT_vs_EV_F07.21429.21429.2 0.000137 13/20 K.LLTQYILNLGK.Y sp|O00203|AP3B1_HUMAN 1 1274.7598 1.63 62593 21429 2 1274.760698 638.3872 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 8.59 3881.9 - 2.95E+06 - - - 0.6856 - 2.442 0.484 - 642.9 1 2 0 0.0009 11 0 0 0 9.34E+06 5.72E+06 - - - 5.0308 1 230117_WJC_METTL3_WT_vs_EV_F07.21430.21430.2 5.80E-06 26-Dec K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.78 62594 21430 2 1651.930875 826.9731 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3882 - 2.28E+06 - - - -0.4673 - 2.37 0.488 - 427.8 1 2 0 -0.0008 14 0 0 0 9.89E+07 1.27E+08 - - - 4.8105 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.21431.21431.2 0.00637 14-Jul M.VLDLDLFR.V "sp|P49591|SYSC_HUMAN,tr|Q5T5C7|Q5T5C7_HUMAN" 2 989.5546 0.86 62595 21431 2 989.557412 495.7846 "Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3" 4.21 3882.1 - 2.52E+06 - - - 2.8599 - 1.703 0.356 - 151 1 2 0 0.0028 8 0 0 0 5.19E+06 6.05E+06 - - - 3.2752 1 230117_WJC_METTL3_WT_vs_EV_F07.21432.21432.2 2.04E-07 13/24 K.DAAIYLVTSLASK[136.11].A sp|P55060|XPO2_HUMAN 1 1358.7537 0.91 62596 21432 2 1358.760633 680.3841 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.83 3882.2 - 2.34E+06 - - - 5.1157 - 2.566 0.439 - 502.5 1 2 0 0.0069 13 0 0 0 9.18E+06 1.01E+07 - - - 4.6998 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.21434.21434.2 0.00225 18-Oct R.GVVLFPWQAR.L sp|Q9Y2S7|PDIP2_HUMAN 1 1171.6502 1.51 62598 21434 2 1171.653717 586.8324 Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1 9.75 3882.4 - 1.47E+06 - - - 2.9898 - 1.919 0.357 - 383 1 2 0 0.0035 10 0 0 0 5.07E+06 3.34E+06 - - - 3.4961 1 230117_WJC_METTL3_WT_vs_EV_F07.21435.21435.2 1.07E-08 15/26 K.LYTLVTYVPVTTFK.N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1643.9174 0.78 62599 21435 2 1643.919868 822.966 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3882.6 - 1.32E+06 - - - 1.4727 - 2.563 0.593 - 746.1 1 2 0 0.0024 14 0 0 0 9.89E+07 1.27E+08 - - - 5.782 1 230117_WJC_METTL3_WT_vs_EV_F07.21436.21436.2 6.08E-07 18-Nov R.VYNALVAFIR.A sp|Q9BW92|SYTM_HUMAN 1 1164.6655 0.36 62600 21436 2 1164.669114 583.34 "Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1" 8.72 3882.7 - 1.29E+06 - - - 3.0781 - 2.206 0.6 - 476.7 1 2 0 0.0036 10 0 0 0 4.27E+06 1.19E+07 - - - 5.6799 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.21437.21437.2 0.00961 14-Aug R.FLTWILNR.Y sp|O43776|SYNC_HUMAN 1 1061.6022 0.94 62601 21437 2 1061.60659 531.8084 "Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1" 9.75 3882.8 - 1.21E+06 - - - 4.1343 - 1.685 0.369 - 230.2 1 2 0 0.0044 8 0 0 0 3.60E+06 3.82E+06 - - - 3.3387 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.21438.21438.2 6.36E-05 20-Oct K.VLAISDLVIYR.T "sp|Q9HBF4|ZFYV1_HUMAN,tr|G3V5N8|G3V5N8_HUMAN" 2 1260.7442 -1 62602 21438 2 1260.748834 631.3794 Zinc finger FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZFYVE1 PE=1 SV=1 5.81 3883 - 1.14E+06 - - - 3.6962 - 2.253 0.425 - 300.6 1 2 0 0.0047 11 0 0 0 0.00E+00 0.00E+00 - - - 4.3759 0.9781 230117_WJC_METTL3_WT_vs_EV_F07.21440.21440.2 0.706 18-Sep R.GVVLFPWQAR[166.11].L sp|Q9Y2S7|PDIP2_HUMAN 1 1181.6585 1.51 62604 21440 2 1181.663286 591.8365 Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1 9.75 3883.2 - 925930 - - - 4.0638 - 1.463 0.099 - 305.3 1 2 0 0.0048 10 0 0 0 5.07E+06 3.34E+06 - - - 0.8328 0.9958 230117_WJC_METTL3_WT_vs_EV_F07.21444.21444.2 0.842 16-Aug K.NIIIALIDR[166.11].L sp|Q96QK1|VPS35_HUMAN 1 1049.6472 1.61 62608 21444 2 1049.650443 525.8309 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 5.84 3883.7 - 616299 - - - 3.042 - 1.644 0.156 - 149.1 1 2 0 0.0032 9 0 0 0 2.35E+06 1.46E+06 - - - 1.6304 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.21446.21446.2 0.000383 24-Sep K.NPLPVTLTNVVFR.L "sp|P22735|TGM1_HUMAN,tr|H0YMQ8|H0YMQ8_HUMAN" 2 1468.8402 999 62610 21446 2 1468.845868 735.4274 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 9.75 3884 - 595075 - - - 3.8595 - 2.111 0.397 - 227.8 1 2 0 0.0057 13 0 0 0 2.09E+06 0.00E+00 - - - 3.8891 1 230117_WJC_METTL3_WT_vs_EV_F07.21451.21451.2 0.000128 14/26 K.LFSLELVDESGEIR[166.11].A sp|P27694|RFA1_HUMAN 1 1615.8333 0.02 62614 21451 2 1615.834812 808.9239 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4 3884.6 - 585635 - - - 0.9524 - 2.719 0.499 - 649.6 1 2 0 0.0015 14 0 0 0 7.67E+05 3.67E+07 - - - 5.2362 0.9721 230117_WJC_METTL3_WT_vs_EV_F07.21455.21455.3 0.0295 13/52 K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.87 62618 21455 3 1651.93817 551.6512 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3885.1 - 883622 - - - 3.9487 - 1.79 0.134 - 65.6 1 2 0 0.0065 14 0 0 0 1.24E+07 1.42E+07 - - - 1.5794 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.21457.21457.2 0.000481 18-Sep K.DWVFLNYTYK[136.11].R "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN" 2 1355.6641 0.11 62620 21457 2 1355.669026 678.8393 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.83 3885.3 - 604510 - - - 3.6049 - 2.065 0.388 - 321.6 1 2 0 0.0049 10 0 0 0 3.73E+05 3.41E+06 - - - 3.9293 0.9598 230117_WJC_METTL3_WT_vs_EV_F07.21461.21461.3 0.015 Nov-48 R.LWSTYLRPLLVVR.T "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN,tr|K7EQG1|K7EQG1_HUMAN" 3 1614.961 -1 62624 21461 3 1614.969619 539.3276 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 10.84 3885.9 - 374300 - - - 5.3475 - 1.453 0.217 - 138.1 1 2 0 0.0086 13 0 0 0 0.00E+00 0.00E+00 - - - 1.97 0.9611 230117_WJC_METTL3_WT_vs_EV_F07.21469.21469.2 0.00969 20-Jul K.EGIPLIILAGK.K sp|P48200|IREB2_HUMAN 1 1122.7012 2.95 62632 21469 2 1122.709257 562.3579 Iron-responsive element-binding protein 2 OS=Homo sapiens OX=9606 GN=IREB2 PE=1 SV=4 6.1 3886.9 - 164158 - - - 7.1355 - 1.293 0.31 - 62.7 1 2 0 0.008 11 0 0 0 1.46E+06 4.95E+05 - - - 2.0233 0.999 230117_WJC_METTL3_WT_vs_EV_F07.21477.21477.2 0.00129 18-Jun R.INPLLDWTYR.D "sp|Q8NFF5|FAD1_HUMAN,tr|Q5T190|Q5T190_HUMAN" 2 1289.6768 -1 62639 21477 2 1289.676533 645.8457 FAD synthase OS=Homo sapiens OX=9606 GN=FLAD1 PE=1 SV=1 5.84 3887.4 - 216420 - - - -0.2241 - 1.434 0.392 - 115.2 1 2 0 -0.0003 10 0 0 0 0.00E+00 0.00E+00 - - - 2.9424 0.9945 230117_WJC_METTL3_WT_vs_EV_F07.21478.21478.2 0.273 14-May K.QFLIDWVR.K "sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 2 1075.5815 0.49 62640 21478 2 1075.582012 538.798 ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2 5.84 3887.5 - 202743 - - - 0.5086 - 1.133 0.216 - 86.8 1 2 0 0.0005 8 0 0 0 1.87E+06 3.84E+06 - - - 1.0128 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.21484.21484.2 0.00684 18-Oct R.TLGWEALLAR.R sp|Q16512|PKN1_HUMAN 1 1128.6291 1.25 62644 21484 2 1128.632856 565.3218 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.66 3888.3 - 331940 - - - 3.2889 - 1.74 0.302 - 257.1 1 2 0 0.0037 10 0 0 0 4.72E+06 3.78E+06 - - - 2.8165 0.999 230117_WJC_METTL3_WT_vs_EV_F07.21489.21489.2 0.0164 18-Nov R.TLGWEALLAR[166.11].R sp|Q16512|PKN1_HUMAN 1 1138.6374 1.27 62649 21489 2 1138.641015 570.326 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.66 3888.9 - 226454 - - - 3.1626 - 1.901 0.336 - 334.8 1 2 0 0.0036 10 0 0 0 4.72E+06 3.71E+06 - - - 3.3146 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21490.21490.2 3.61E-05 22-Dec R.ALGATFGPLLLR.A "sp|O00459|P85B_HUMAN,tr|E9PFP1|E9PFP1_HUMAN" 2 1227.7339 2.49 62650 21490 2 1227.735598 614.8742 Phosphatidylinositol 3-kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PIK3R2 PE=1 SV=2 9.79 3889.1 - 186634 - - - 1.348 - 2.301 0.444 - 418.2 1 2 0 0.0017 12 0 0 0 9.82E+05 3.95E+05 - - - 4.5125 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.21492.21492.2 0.00633 18-Jul K.YVEVFFPQFK.L sp|O75635|SPB7_HUMAN 1 1302.6649 2.25 62652 21492 2 1302.662069 652.3397 Serpin B7 OS=Homo sapiens OX=9606 GN=SERPINB7 PE=1 SV=1 6 3889.3 - 169134 - - - -2.1433 - 1.563 0.315 - 148.9 1 2 0 -0.0028 10 0 0 0 4.67E+06 2.07E+06 - - - 2.6133 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21493.21493.2 0.000259 20-Oct K.TLC[160.03]PLC[160.03]FSILK.G "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1350.704 1.26 62653 21493 2 1350.706661 676.3593 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 7.74 3889.4 - 168883 - - - 1.9953 - 1.927 0.476 - 248 1 2 0 0.0027 11 0 0 0 4.78E+06 3.80E+06 - - - 4.3304 1 230117_WJC_METTL3_WT_vs_EV_F07.21496.21496.2 2.90E-14 22/34 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.83 62656 21496 2 1926.001198 964.0089 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3889.8 - 136075 - - - -1.1012 - 4.38 0.704 - 1533.9 1 2 0 -0.0021 18 0 0 0 4.01E+07 4.81E+07 - - - 7.8715 1 230117_WJC_METTL3_WT_vs_EV_F07.21497.21497.2 3.27E-11 20/34 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.83 62657 21497 2 1936.017145 969.0131 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3890 - 122305 - - - 2.8698 - 4.106 0.678 - 1017.5 1 2 0 0.0056 18 0 0 0 4.01E+07 4.81E+07 - - - 7.5195 1 230117_WJC_METTL3_WT_vs_EV_F07.21505.21505.3 3.55E-11 19/68 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.83 62663 21505 3 1936.01386 646.3445 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3891.1 - 362523 - - - 1.173 - 3.113 0.632 - 387.6 1 2 0 0.0023 18 0 0 0 2.47E+07 2.97E+07 - - - 8.4133 1 230117_WJC_METTL3_WT_vs_EV_F07.21506.21506.2 3.70E-05 20-Nov R.EALDVLGAVLK[136.11].A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1134.674 1.41 62664 21506 2 1134.675019 568.3443 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3891.1 - 116043 - - - 0.9201 - 2.194 0.51 - 387.3 1 2 0 0.001 11 0 0 0 7.87E+07 5.58E+07 - - - 4.9331 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.21508.21508.2 0.0648 16-Aug R.MDPAWHPWL.- "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1151.5222 - 62666 21508 2 1151.523444 576.7684 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 5.06 3891.3 - 177765 - - - 1.049 - 1.312 0.32 - 134.5 1 2 0 0.0012 9 0 0 0 - - - - - 2.1898 1 230117_WJC_METTL3_WT_vs_EV_F07.21510.21510.2 0.004 15/28 R.TIAIIAEGIPEALTR.K sp|P53396|ACLY_HUMAN 1 1566.8981 1.73 62668 21510 2 1566.900174 784.4563 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.53 3891.5 - 31627.7 - - - 1.3185 - 2.89 0.497 - 738.7 1 2 0 0.0021 15 0 0 0 1.60E+06 9.22E+05 - - - 5.3203 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.21513.21513.3 0.000176 15/40 K.LPLGLLLHPFK.D sp|O95486|SC24A_HUMAN 1 1246.7802 0.53 62671 21513 3 1246.781965 416.6007 Protein transport protein Sec24A OS=Homo sapiens OX=9606 GN=SEC24A PE=1 SV=2 8.76 3891.9 - 37912.1 - - - 1.4437 - 2.954 0.37 - 383.8 1 2 0 0.0018 11 0 0 0 1.12E+06 2.14E+06 - - - 5.7417 1 230117_WJC_METTL3_WT_vs_EV_F07.21516.21516.3 1.70E-09 23/68 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.83 62672 21516 3 1926.010253 643.0084 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3892.4 - 7.67E+06 - - - 3.6002 - 3.37 0.59 - 460.9 1 2 0 0.0069 18 0 0 0 2.47E+07 2.98E+07 - - - 8.1413 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21518.21518.2 0.0192 22-Oct R.LFQVEYAIEAIK.L sp|P28066|PSA5_HUMAN 1 1422.7759 2.14 62674 21518 2 1422.778984 712.3952 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 4.53 3892.5 - 6.10E+06 - - - 2.1901 - 2.231 0.381 - 313.8 1 2 0 0.0031 12 0 0 0 2.90E+07 1.35E+07 - - - 3.9655 1 230117_WJC_METTL3_WT_vs_EV_F07.21519.21519.2 0.000785 13/18 K.C[160.03]MQLTDFILK[136.11].F "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1275.6447 0.67 62675 21519 2 1275.647904 638.8296 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.83 3892.5 - 2.99E+06 - - - 2.5383 - 2.324 0.539 - 499.4 1 2 0 0.0032 10 0 0 0 1.72E+07 2.56E+07 - - - 5.3749 1 230117_WJC_METTL3_WT_vs_EV_F07.21520.21520.3 1.31E-07 17/52 K.LPLFPEPLHVFAPR.A "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|K7ENW7|K7ENW7_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 7 1631.9188 0.75 62676 21520 3 1631.922267 544.9802 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 6.75 3892.6 - 2.54E+06 - - - 2.1343 - 3.114 0.539 - 472.7 1 2 0 0.0035 14 0 0 0 9.75E+06 1.30E+07 - - - 7.5671 1 230117_WJC_METTL3_WT_vs_EV_F07.21521.21521.2 4.06E-05 13/18 K.C[160.03]MQLTDFILK.F "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1267.6305 0.67 62677 21521 2 1267.633232 634.8225 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.83 3892.7 - 2.10E+06 - - - 2.182 - 2.435 0.538 - 539.9 1 2 0 0.0028 10 0 0 0 1.72E+07 2.56E+07 - - - 5.4979 1 230117_WJC_METTL3_WT_vs_EV_F07.21524.21524.2 9.37E-07 14/24 R.VLGATLLPDLIQK[136.11].V "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN,tr|H0YDG0|H0YDG0_HUMAN" 5 1387.853 1.61 62680 21524 2 1387.855983 694.9338 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.81 3893.1 - 1.17E+06 - - - 2.1479 - 2.583 0.518 - 577.8 1 2 0 0.003 13 0 0 0 1.03E+07 6.36E+06 - - - 5.3015 1 230117_WJC_METTL3_WT_vs_EV_F07.21531.21531.2 8.36E-08 13/24 K.YVFLDPLAGAVTK[136.11].T "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|A8MWX3|WASH4_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 6 1400.7795 2.18 62687 21531 2 1400.781155 701.397 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 5.83 3894 - 597155 - - - 1.1793 - 2.441 0.596 - 433.1 1 2 0 0.0017 13 0 0 0 2.13E+07 9.78E+06 - - - 5.7329 1 230117_WJC_METTL3_WT_vs_EV_F07.21533.21533.2 3.77E-09 13/26 R.VIVSDVQESFIWVR.Y sp|Q15393|SF3B3_HUMAN 1 1675.8934 1.18 62689 21533 2 1675.897233 838.954 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3894.3 - 485405 - - - 2.3128 - 2.793 0.553 - 435.5 1 2 0 0.0039 14 0 0 0 7.10E+06 6.03E+06 - - - 5.7017 1 230117_WJC_METTL3_WT_vs_EV_F07.21534.21534.2 1.49E-06 14/26 R.VIVSDVQESFIWVR[166.11].Y sp|Q15393|SF3B3_HUMAN 1 1685.9016 1.18 62690 21534 2 1685.904471 843.9581 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3894.4 - 426538 - - - 1.6869 - 2.897 0.597 - 568.3 1 2 0 0.0028 14 0 0 0 7.10E+06 6.03E+06 - - - 6.1188 1 230117_WJC_METTL3_WT_vs_EV_F07.21537.21537.2 8.47E-06 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 62692 21537 2 1603.766783 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3894.7 - 3.63E+07 - - - 1.7727 - 1.659 0.575 - 212.5 1 2 0 0.0028 12 0 0 0 2.71E+08 0.00E+00 - - - 4.619 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21539.21539.2 7.95E-05 18-Dec K.LLEPVLLLGK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1093.7111 1.59 62694 21539 2 1093.71374 547.8628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3894.8 - 1.81E+07 - - - 2.4293 - 2.511 0.301 - 447.4 1 2 0 0.0027 10 0 0 0 9.07E+08 5.69E+08 - - - 3.8333 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21540.21540.2 0.0323 13/18 K.LLEPVLLLGK[136.11].E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1101.7253 1.59 62695 21540 2 1101.727611 551.8699 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3894.9 - 1.30E+07 - - - 2.113 - 2.494 0.318 - 538.7 1 2 0 0.0023 10 0 0 0 9.07E+08 5.69E+08 - - - 3.94 1 230117_WJC_METTL3_WT_vs_EV_F07.21543.21543.2 1.58E-05 20-Nov R.FVASYLEYAFR.K sp|Q96GM8|TOE1_HUMAN 1 1364.6765 1.53 62698 21543 2 1364.679314 683.3455 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 6 3895.2 - 938664 - - - 2.0708 - 2.124 0.482 - 399.6 1 2 0 0.0028 11 0 0 0 3.40E+06 2.22E+06 - - - 4.638 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.21547.21547.2 0.00883 14-Jul K.SFDLLILK[136.11].E "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 955.5834 0.94 62702 21547 2 955.585622 478.799 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 5.55 3895.7 - 536564 - - - 2.3577 - 1.467 0.323 - 139.1 1 2 0 0.0023 8 0 0 0 6.12E+06 6.53E+06 - - - 2.5817 1 230117_WJC_METTL3_WT_vs_EV_F07.21548.21548.2 4.91E-06 16-Oct R.DIDAFWLQR.Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1162.5771 1.56 62703 21548 2 1162.579304 582.2958 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3895.9 - 466536 - - - 1.8889 - 1.914 0.533 - 377.7 1 2 0 0.0022 9 0 0 0 3.18E+07 2.03E+07 - - - 4.8552 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21551.21551.2 7.41E-05 14-Jul K.NFAFLEFR[166.11].S "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1052.5319 1.48 62706 21551 2 1052.534021 527.2732 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3896.3 - 347581 - - - 2.0284 - 1.603 0.441 - 208.9 1 2 0 0.0021 8 0 0 0 2.47E+07 1.68E+07 - - - 3.7207 0.9816 230117_WJC_METTL3_WT_vs_EV_F07.21552.21552.2 0.00354 14-Jul K.YLFDLPLK.V sp|Q5VUJ6|LRCH2_HUMAN 1 1007.5692 3.36 62707 21552 2 1007.576334 504.7919 Leucine-rich repeat and calponin homology domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LRCH2 PE=1 SV=2 5.83 3896.4 - 335465 - - - 7.1112 - 1.308 0.404 - 140.4 1 2 0 0.0072 8 0 0 0 3.34E+06 9.94E+05 - - - 2.8325 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.21556.21556.3 3.31E-05 16/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 -1 62710 21556 3 1603.768285 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3896.9 - 1.69E+06 - - - 2.7093 - 2.721 0.478 - 381.4 1 2 0 0.0043 12 0 0 0 0.00E+00 0.00E+00 - - - 6.6426 1 230117_WJC_METTL3_WT_vs_EV_F07.21558.21558.2 7.98E-06 13/24 R.LDPETLESLGLIK[136.11].Q "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 1434.8061 1.99 62712 21558 2 1434.810768 718.4103 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 4.14 3897.1 - 1.04E+06 - - - 3.245 - 2.388 0.53 - 583.8 1 2 0 0.0047 13 0 0 0 1.97E+07 9.87E+06 - - - 5.1882 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21559.21559.2 0.00306 16-Oct R.DIDAFWLQR[166.11].Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1172.5854 1.56 62713 21559 2 1172.587243 587.3 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3897.3 - 955459 - - - 1.5905 - 2.012 0.35 - 373.3 1 2 0 0.0019 9 0 0 0 3.17E+07 2.03E+07 - - - 3.6481 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.21560.21560.2 0.000509 14-Jul K.NFAFLEFR.S "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1042.5236 1.48 62714 21560 2 1042.526183 522.2691 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3897.4 - 933914 - - - 2.4623 - 1.572 0.405 - 236.3 1 2 0 0.0026 8 0 0 0 2.51E+07 1.70E+07 - - - 3.3958 1 230117_WJC_METTL3_WT_vs_EV_F07.21561.21561.2 9.40E-05 18-Nov K.QEVPIIIVFR[166.11].A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1222.7313 1.31 62715 21561 2 1222.734592 612.3729 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3897.5 - 670693 - - - 2.6809 - 2.202 0.508 - 494.6 1 2 0 0.0033 10 0 0 0 2.35E+07 1.79E+07 - - - 4.9954 1 230117_WJC_METTL3_WT_vs_EV_F07.21562.21562.2 9.80E-05 18-Nov K.QEVPIIIVFR.A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1212.723 1.31 62716 21562 2 1212.727664 607.3688 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3897.7 - 629149 - - - 3.8096 - 2.275 0.529 - 452.1 1 2 0 0.0046 10 0 0 0 2.35E+07 1.79E+07 - - - 5.2411 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21563.21563.2 9.32E-07 22-Nov R.LGAPGFAWEPFR.G "sp|Q9HCM7|FBSL_HUMAN,tr|A0A3B3IRR3|A0A3B3IRR3_HUMAN,tr|A0A7P0Z485|A0A7P0Z485_HUMAN" 3 1346.6772 1.79 62717 21563 2 1346.67966 674.3459 Fibrosin-1-like protein OS=Homo sapiens OX=9606 GN=FBRSL1 PE=1 SV=4 6 3897.8 - 547741 - - - 1.8586 - 2.404 0.429 - 550 1 2 0 0.0025 12 0 0 0 2.23E+06 1.24E+06 - - - 4.5167 1 230117_WJC_METTL3_WT_vs_EV_F07.21564.21564.2 0.000292 22-Nov R.EVAAGYLVPLLR.S sp|Q13395|TARB1_HUMAN 1 1299.7551 2.36 62718 21564 2 1299.75867 650.8848 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6.1 3897.9 - 541544 - - - 2.7674 - 2.472 0.477 - 571.5 1 2 0 0.0036 12 0 0 0 5.13E+06 2.17E+06 - - - 4.9443 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.21566.21566.2 0.00276 14-Aug K.SFDLLILK.E "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 947.5692 0.94 62720 21566 2 947.571359 474.7919 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 5.55 3898.2 - 458803 - - - 2.3112 - 1.608 0.312 - 196.1 1 2 0 0.0022 8 0 0 0 6.12E+06 6.53E+06 - - - 2.7773 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.21568.21568.2 0.00446 16-Oct R.IPILFFANK.M "sp|Q9H0F7|ARL6_HUMAN,tr|A0A0J9YXT0|A0A0J9YXT0_HUMAN,tr|H7C5H6|H7C5H6_HUMAN" 3 1061.6274 2.05 62722 21568 2 1061.631713 531.821 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3898.5 - 375102 - - - 4.1069 - 2.205 0.4 - 363.1 1 2 0 0.0044 9 0 0 0 5.08E+06 2.48E+06 - - - 4.2816 1 230117_WJC_METTL3_WT_vs_EV_F07.21569.21569.2 3.43E-09 24-Dec K.FDFPVSYLPGPVK.A "sp|Q9NXE4|NSMA3_HUMAN,tr|A0A7P0T8J0|A0A7P0T8J0_HUMAN,tr|A0A7P0Z453|A0A7P0Z453_HUMAN,tr|C9J647|C9J647_HUMAN,tr|A0A7P0TAZ0|A0A7P0TAZ0_HUMAN,tr|A0A7P0T9J6|A0A7P0T9J6_HUMAN,tr|A0A7P0TB24|A0A7P0TB24_HUMAN" 7 1464.7653 1.86 62723 21569 2 1464.765107 733.3899 Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3 5.83 3898.6 - 345442 - - - -0.1338 - 2.3 0.66 - 337.3 1 2 0 -0.0002 13 0 0 0 4.32E+06 2.32E+06 - - - 6.0534 1 230117_WJC_METTL3_WT_vs_EV_F07.21570.21570.2 5.59E-06 24-Sep K.FDFPVSYLPGPVK[136.11].A "sp|Q9NXE4|NSMA3_HUMAN,tr|A0A7P0T8J0|A0A7P0T8J0_HUMAN,tr|A0A7P0Z453|A0A7P0Z453_HUMAN,tr|C9J647|C9J647_HUMAN,tr|A0A7P0TAZ0|A0A7P0TAZ0_HUMAN,tr|A0A7P0T9J6|A0A7P0T9J6_HUMAN,tr|A0A7P0TB24|A0A7P0TB24_HUMAN" 7 1472.7795 2.1 62724 21570 2 1472.780265 737.397 Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3 5.83 3898.7 - 231632 - - - 0.5174 - 1.825 0.597 - 168.7 1 2 0 0.0008 13 0 0 0 5.10E+06 2.42E+06 - - - 4.9942 1 230117_WJC_METTL3_WT_vs_EV_F07.21571.21571.2 3.60E-05 20-Oct K.DPWDAVLLEER[166.11].S "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 1351.6648 1.88 62725 21571 2 1351.658234 676.8397 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 3.92 3898.8 - 229682 - - - -4.8215 - 1.988 0.506 - 351.7 1 2 0 -0.0065 11 0 0 0 4.99E+06 2.65E+06 - - - 4.6351 1 230117_WJC_METTL3_WT_vs_EV_F07.21573.21573.2 1.25E-06 13/36 R.LFVSDGVPGC[160.03]LPVLAAAGR.A "sp|P56192|SYMC_HUMAN,tr|F8W0S4|F8W0S4_HUMAN,tr|F8W0M7|F8W0M7_HUMAN,tr|F8VPL7|F8VPL7_HUMAN,tr|F5H2V6|F5H2V6_HUMAN,tr|F8VS26|F8VS26_HUMAN,tr|F8VZZ9|F8VZZ9_HUMAN" 7 1898.0084 1.69 62727 21573 2 1898.007138 950.0115 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 5.83 3899.1 - 208876 - - - -0.667 - 2.557 0.533 - 181 1 2 0 -0.0013 19 0 0 0 3.89E+06 2.31E+06 - - - 5.2855 1 230117_WJC_METTL3_WT_vs_EV_F07.21577.21577.2 9.31E-06 20-Oct R.EALDVLGAVLK.A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1126.6598 1.41 62730 21577 2 1126.661856 564.3372 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3899.6 - 1.45E+07 - - - 1.8471 - 2.105 0.499 - 353.8 1 2 0 0.0021 11 0 0 0 7.87E+07 5.58E+07 - - - 4.7395 0.8826 230117_WJC_METTL3_WT_vs_EV_F07.21580.21580.2 0.505 14-Jul N.GVSQLIQR.E sp|P48201|AT5G3_HUMAN 1 899.5189 0.85 62733 21580 2 899.518361 450.7667 "ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1" 9.75 3899.8 - 5.97E+06 - - - -0.5603 - 1.685 0.27 - 209.3 1 1 0 -0.0005 8 0 0 0 9.58E+07 1.13E+08 - - - 2.6087 1 230117_WJC_METTL3_WT_vs_EV_F07.21582.21582.2 1.18E-06 24-Oct K.TVQTAVFLYSLYK.E "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 1531.8286 1.08 62735 21582 2 1531.827899 766.9216 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.17 3899.9 - 2.69E+06 - - - -0.4785 - 2.357 0.537 - 253 1 2 0 -0.0007 13 0 0 0 8.05E+06 7.48E+06 - - - 5.2076 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21583.21583.2 7.96E-05 30-Aug K.TFVNITPAEVGVLVGK.D "sp|P07737|PROF1_HUMAN,tr|I3L3D5|I3L3D5_HUMAN" 2 1642.9294 0.9 62736 21583 2 1642.930515 822.472 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 5.66 3900 - 1.68E+06 - - - 0.6738 - 1.732 0.437 - 162 1 2 0 0.0011 16 0 0 0 4.85E+06 5.37E+06 - - - 3.6188 0.9489 230117_WJC_METTL3_WT_vs_EV_F07.21584.21584.2 0.437 18-Jul K.EYLPFLNTLK[136.11].K "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN" 12 1244.6896 1.58 62737 21584 2 1244.686918 623.3521 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 6.1 3900.1 - 1.57E+06 - - - -2.1748 - 1.204 0.131 - 103 1 2 0 -0.0027 10 0 0 0 6.99E+06 4.41E+06 - - - 0.5259 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.21585.21585.2 0.000414 13/24 K.ALEVAEYLTPVLK.E "sp|Q9NT62|ATG3_HUMAN,tr|F8WDI0|F8WDI0_HUMAN" 2 1444.8177 -1 62738 21585 2 1444.82278 723.4161 Ubiquitin-like-conjugating enzyme ATG3 OS=Homo sapiens OX=9606 GN=ATG3 PE=1 SV=1 4.53 3900.1 - 1.41E+06 - - - 3.4932 - 2.607 0.404 - 594.7 1 2 0 0.005 13 0 0 0 0.00E+00 0.00E+00 - - - 4.4826 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21586.21586.2 0.0138 22-Sep R.EVAAGYLVPLLR[166.11].S sp|Q13395|TARB1_HUMAN 1 1309.7633 -1 62739 21586 2 1309.763574 655.8889 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6.1 3900.2 - 1.40E+06 - - - 0.1764 - 2.137 0.397 - 287.6 1 2 0 0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 3.9713 1 230117_WJC_METTL3_WT_vs_EV_F07.21587.21587.2 8.23E-05 24-Dec K.LLLDTFEYQGLVK[136.11].H "sp|Q7Z7K6|CENPV_HUMAN,tr|A0A0M3HER2|A0A0M3HER2_HUMAN" 2 1545.8534 1.94 62740 21587 2 1545.853478 773.934 Centromere protein V OS=Homo sapiens OX=9606 GN=CENPV PE=1 SV=1 4.37 3900.3 - 1.22E+06 - - - 0.053 - 2.182 0.515 - 371.9 1 2 0 0.0001 13 0 0 0 7.60E+06 3.91E+06 - - - 4.8473 1 230117_WJC_METTL3_WT_vs_EV_F07.21593.21593.2 6.11E-09 14/24 R.LLGNTFVALSDLR.C "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1417.7929 2.02 62744 21593 2 1417.793819 709.9037 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.84 3901.1 - 1.02E+06 - - - 0.6376 - 2.657 0.625 - 670.7 1 2 0 0.0009 13 0 0 0 4.40E+07 2.17E+07 - - - 6.165 1 230117_WJC_METTL3_WT_vs_EV_F07.21598.21598.2 1.52E-05 24-Nov K.VSASPLLYTLIEK[136.11].T "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1440.8319 2.14 62749 21598 2 1440.835828 721.4232 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 5.97 3901.7 - 147868 - - - 2.7033 - 2.642 0.498 - 363.5 1 2 0 0.0039 13 0 0 0 1.60E+07 7.47E+06 - - - 5.2115 0.9973 230117_WJC_METTL3_WT_vs_EV_F07.21601.21601.2 0.000117 Sep-36 R.LFVSDGVPGC[160.03]LPVLAAAGR[166.11].A "sp|P56192|SYMC_HUMAN,tr|F8W0S4|F8W0S4_HUMAN,tr|F8W0M7|F8W0M7_HUMAN,tr|F8VPL7|F8VPL7_HUMAN,tr|F5H2V6|F5H2V6_HUMAN,tr|F8VS26|F8VS26_HUMAN,tr|F8VZZ9|F8VZZ9_HUMAN" 7 1908.0167 1.69 62752 21601 2 1908.011068 955.0156 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 5.83 3902.1 - 63645.1 - - - -2.9381 - 1.751 0.506 - 82.4 1 2 0 -0.0056 19 0 0 0 3.89E+06 2.31E+06 - - - 4.1538 1 230117_WJC_METTL3_WT_vs_EV_F07.21606.21606.2 3.46E-06 18-Dec K.LFEISDIVIK.D sp|Q9NSD9|SYFB_HUMAN 1 1175.6802 3.72 62755 21606 2 1176.677296 588.8474 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 4.37 3902.7 - 1.03E+06 - - - 848.1218 - 2.301 0.497 - 385.1 1 2 0 0.9971 10 0 0 0 1.62E+07 4.34E+06 - - - 4.7249 1 230117_WJC_METTL3_WT_vs_EV_F07.21609.21609.2 6.61E-07 13/24 K.VFSATLGLVDIVK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1368.8108 1.12 62758 21609 2 1368.813299 685.4127 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3903.1 - 533781 - - - 1.8235 - 2.574 0.564 - 451 1 2 0 0.0025 13 0 0 0 5.41E+07 4.83E+07 - - - 5.6325 1 230117_WJC_METTL3_WT_vs_EV_F07.21610.21610.2 1.29E-06 15/24 K.VFSATLGLVDIVK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1360.7966 1.12 62759 21610 2 1360.7999 681.4056 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3903.3 - 511283 - - - 2.4228 - 2.588 0.565 - 587.5 1 2 0 0.0033 13 0 0 0 5.58E+07 4.98E+07 - - - 5.6535 1 230117_WJC_METTL3_WT_vs_EV_F07.21613.21613.2 8.22E-07 13/24 K.LEVAPISDIIAIK.S "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 6 1380.8228 2.78 62762 21613 2 1380.824153 691.4187 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 4.37 3903.6 - 429713 - - - 0.9668 - 2.421 0.533 - 379.6 1 2 0 0.0013 13 0 0 0 3.07E+07 1.11E+07 - - - 5.2466 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.21614.21614.3 0.000243 Dec-48 R.LLGNTFVALSDLR.C "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1417.7929 3.78 62763 21614 3 1417.79665 473.6049 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.84 3903.8 - 361269 - - - 2.6344 - 2.244 0.438 - 195.2 1 2 0 0.0037 13 0 0 0 2.62E+06 6.95E+05 - - - 5.6137 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.21616.21616.2 1.33 16-Sep R.LLPDFLLER[166.11].R "sp|Q12894|IFRD2_HUMAN,tr|H7C444|H7C444_HUMAN,tr|A0A0R4J2F6|A0A0R4J2F6_HUMAN" 3 1124.6469 0.03 62765 21616 2 1124.650019 563.3307 Interferon-related developmental regulator 2 OS=Homo sapiens OX=9606 GN=IFRD2 PE=1 SV=3 4.37 3904 - 306482 - - - 2.7591 - 1.961 0.191 - 149.7 2 2 0 0.0031 9 0 0 0 2.02E+06 6.72E+07 - - - 2.2646 1 230117_WJC_METTL3_WT_vs_EV_F07.21632.21632.2 0.000629 22-Dec K.IILDLISESPIK.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1339.7963 1.15 62778 21632 2 1339.798986 670.9054 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3905.7 - 4.18E+06 - - - 2.0279 - 2.407 0.478 - 439.5 1 2 0 0.0027 12 0 0 0 2.43E+08 2.11E+08 - - - 4.8818 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21633.21633.2 0.000277 16-Aug R.FWYFVSQLK[136.11].K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1224.6423 0.65 62779 21633 2 1224.644342 613.3284 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3905.8 - 4.08E+06 - - - 1.6829 - 1.536 0.444 - 237.9 1 2 0 0.0021 9 0 0 0 2.06E+07 3.14E+07 - - - 3.5614 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.21635.21635.2 0.000369 16-Sep R.FWYFVSQLK.K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1216.6281 0.66 62781 21635 2 1216.632604 609.3213 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3905.9 - 1.85E+06 - - - 3.7177 - 1.828 0.494 - 282.2 1 2 0 0.0045 9 0 0 0 2.06E+07 3.14E+07 - - - 4.4334 1 230117_WJC_METTL3_WT_vs_EV_F07.21636.21636.2 4.01E-10 26-Nov K.FGGDFLVYPGDPLR.F "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN" 4 1551.7722 1.48 62782 21636 2 1551.772295 776.8934 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.21 3905.9 - 1.63E+06 - - - 0.0748 - 2.43 0.639 - 392.5 1 2 0 0.0001 14 0 0 0 9.22E+06 6.23E+06 - - - 5.9887 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21637.21637.2 0.0022 28-Oct K.IVFVPGC[160.03]SIPLTIVK[136.11].S sp|P54136|SYRC_HUMAN 1 1649.967 1.64 62783 21637 2 1649.966256 825.9908 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3906 - 1.46E+06 - - - -0.443 - 1.963 0.484 - 205.6 1 2 0 -0.0007 15 0 0 0 2.06E+07 1.25E+07 - - - 4.2738 0.9955 230117_WJC_METTL3_WT_vs_EV_F07.21639.21639.2 0.0238 16-Aug K.TVFDNFFIK.K sp|Q9H040|SPRTN_HUMAN 1 1129.5808 3.96 62785 21639 2 1129.578529 565.7977 DNA-dependent metalloprotease SPRTN OS=Homo sapiens OX=9606 GN=SPRTN PE=1 SV=2 5.5 3906.1 - 1.02E+06 - - - -2.0078 - 1.377 0.348 - 128.7 1 2 0 -0.0023 9 0 0 0 2.77E+06 6.98E+05 - - - 2.5361 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21640.21640.2 0.00685 24-Nov K.LDNLLLDTEGFVK.L sp|Q16513|PKN2_HUMAN 1 1475.7872 1.8 62786 21640 2 1475.788723 738.9009 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.03 3906.2 - 987298 - - - 1.0584 - 2.034 0.354 - 371.3 1 2 0 0.0016 13 0 0 0 2.67E+06 1.48E+06 - - - 3.4774 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.21644.21644.2 7.67E-05 24-Dec K.LDNLLLDTEGFVK[136.11].L sp|Q16513|PKN2_HUMAN 1 1483.8014 1.8 62790 21644 2 1483.80078 742.908 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.03 3906.5 - 632755 - - - -0.3916 - 2.15 0.383 - 334.9 1 2 0 -0.0006 13 0 0 0 2.67E+06 1.48E+06 - - - 3.8343 0.9855 230117_WJC_METTL3_WT_vs_EV_F07.21645.21645.2 0.0646 16-Aug R.LDLLPFYAR[166.11].L sp|Q9HAU5|RENT2_HUMAN 1 1116.6207 1.65 62791 21645 2 1116.617586 559.3176 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 5.84 3906.5 - 621292 - - - -2.7897 - 1.759 0.159 - 153.3 1 2 0 -0.0031 9 0 0 0 2.39E+06 1.45E+06 - - - 1.8482 0.9976 230117_WJC_METTL3_WT_vs_EV_F07.21648.21648.2 0.00924 14-Jun R.FDMIFIVK.D "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1011.5463 -1 62793 21648 2 1011.545621 506.7804 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 5.84 3906.9 - 157308 - - - -0.696 - 1.439 0.293 - 83 1 2 0 -0.0007 8 0 0 0 0.00E+00 0.00E+00 - - - 2.3025 1 230117_WJC_METTL3_WT_vs_EV_F07.21650.21650.2 9.14E-06 28-Dec K.IVFVPGC[160.03]SIPLTIVK.S sp|P54136|SYRC_HUMAN 1 1641.9528 1.64 62794 21650 2 1641.953069 821.9837 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3907.1 - 3.04E+06 - - - 0.1717 - 2.324 0.526 - 307.4 1 2 0 0.0003 15 0 0 0 2.06E+07 1.25E+07 - - - 4.9992 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21653.21653.2 4.06E-05 26-Dec K.EIGLLADEIEIYGK.S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1561.8239 2.39 62797 21653 2 1561.824539 781.9192 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4 3907.5 - 1.02E+06 - - - 0.3835 - 2.163 0.41 - 316.3 1 2 0 0.0006 14 0 0 0 2.86E+06 1.19E+06 - - - 4.0051 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.21656.21656.2 0.0156 20-Dec K.NFGLIASYLER.K "sp|O75376|NCOR1_HUMAN,tr|E7EVU5|E7EVU5_HUMAN,tr|J3KS51|J3KS51_HUMAN,tr|E7EW50|E7EW50_HUMAN,tr|A0A088AWL3|A0A088AWL3_HUMAN" 5 1281.6717 2.04 62800 21656 2 1281.675843 641.8431 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 6 3907.8 - 627319 - - - 3.2036 - 2.136 0.348 - 404.2 1 2 0 0.0041 11 0 0 0 4.82E+06 2.37E+06 - - - 3.6631 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21657.21657.2 3.87E-05 18-Aug K.VVLPTFILER[166.11].R sp|Q96SU4|OSBL9_HUMAN 1 1195.7204 1.46 62801 21657 2 1195.721165 598.8675 Oxysterol-binding protein-related protein 9 OS=Homo sapiens OX=9606 GN=OSBPL9 PE=1 SV=2 5.97 3908 - 480396 - - - 0.6272 - 1.756 0.484 - 200.7 1 2 0 0.0008 10 0 0 0 4.64E+06 3.18E+06 - - - 4.1872 0.9932 230117_WJC_METTL3_WT_vs_EV_F07.21659.21659.2 0.0134 16-Sep R.LLPDFLLER.R "sp|Q12894|IFRD2_HUMAN,tr|H7C444|H7C444_HUMAN,tr|A0A0R4J2F6|A0A0R4J2F6_HUMAN" 3 1114.6386 0.08 62803 21659 2 1114.635525 558.3266 Interferon-related developmental regulator 2 OS=Homo sapiens OX=9606 GN=IFRD2 PE=1 SV=3 4.37 3908.2 - 371606 - - - -2.8 - 1.831 0.248 - 214.7 1 2 0 -0.0031 9 0 0 0 1.67E+06 2.04E+07 - - - 2.6216 1 230117_WJC_METTL3_WT_vs_EV_F07.21670.21670.2 6.37E-07 16/24 R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 1.79 62812 21670 2 1448.794605 725.4024 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3909.4 - 354725 - - - 2.9811 - 3.264 0.539 - 1155.7 1 2 0 0.0043 13 0 0 0 8.15E+07 4.56E+07 - - - 6.0568 1 230117_WJC_METTL3_WT_vs_EV_F07.21672.21672.2 1.07E-06 13/26 K.VLLLSSPGLEELYR[166.11].C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1597.8955 1.11 62814 21672 2 1597.89615 799.955 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3909.7 - 93547.3 - - - 0.4199 - 2.674 0.479 - 462.1 1 2 0 0.0007 14 0 0 0 7.80E+06 7.05E+06 - - - 5.0469 1 230117_WJC_METTL3_WT_vs_EV_F07.21675.21675.2 0.00851 16/24 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.79 62816 21675 2 1438.781832 720.3983 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3910 - 7.41E+06 - - - -0.1279 - 3.285 0.489 - 935.2 1 2 0 -0.0002 13 0 0 0 8.15E+07 4.56E+07 - - - 5.7052 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.21676.21676.2 8.06E-05 14/26 K.VLLLSSPGLEELYR.C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1587.8872 1.11 62817 21676 2 1587.883186 794.9509 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3910.2 - 1.96E+06 - - - -2.5336 - 2.574 0.379 - 602.8 1 2 0 -0.004 14 0 0 0 7.80E+06 7.05E+06 - - - 4.2116 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.21677.21677.2 8.97E-06 22-Nov R.YFPTQALNFAFK[136.11].D "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 1453.7485 1.14 62818 21677 2 1453.745137 727.8815 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.59 3910.3 - 1.08E+06 - - - -2.3388 - 1.984 0.484 - 385.6 1 2 0 -0.0034 12 0 0 0 1.40E+08 1.23E+08 - - - 4.4174 1 230117_WJC_METTL3_WT_vs_EV_F07.21678.21678.2 0.000172 20-Oct K.LPDVYGVFQFK.V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1311.6863 0.91 62819 21678 2 1311.686129 656.8504 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.83 3910.4 - 731620 - - - -0.1487 - 2.2 0.485 - 323.6 1 2 0 -0.0002 11 0 0 0 1.00E+07 1.10E+07 - - - 4.7561 1 230117_WJC_METTL3_WT_vs_EV_F07.21679.21679.2 0.000349 16-Dec R.IDLAVLLGK.T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 940.5957 2.07 62820 21679 2 940.595167 471.3051 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3910.6 - 717275 - - - -0.5858 - 2.394 0.512 - 366.5 1 2 0 -0.0006 9 0 0 0 1.84E+08 8.89E+07 - - - 5.348 1 230117_WJC_METTL3_WT_vs_EV_F07.21681.21681.2 4.74E-05 13/20 K.LPDVYGVFQFK[136.11].V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1319.7005 1 62822 21681 2 1319.702084 660.8575 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.83 3910.8 - 609794 - - - 1.1821 - 2.312 0.544 - 621.5 1 2 0 0.0016 11 0 0 0 1.10E+07 1.10E+07 - - - 5.3258 1 230117_WJC_METTL3_WT_vs_EV_F07.21683.21683.2 0.00812 13/16 R.IDLAVLLGK[136.11].T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 948.6099 2.07 62824 21683 2 948.609499 475.3122 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3911.1 - 487117 - - - -0.4417 - 2.488 0.495 - 421.5 1 2 0 -0.0004 9 0 0 0 1.84E+08 8.89E+07 - - - 5.3339 0.9998 230117_WJC_METTL3_WT_vs_EV_F07.21685.21685.3 7.19E-05 13/48 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.98 62826 21685 3 1438.781255 480.6013 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3911.3 - 365137 - - - -0.5289 - 2.716 0.376 - 259.3 1 2 0 -0.0008 13 0 0 0 2.34E+06 1.18E+06 - - - 5.4408 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.21687.21687.2 0.000325 24-Aug R.FDNVLPVSLAFDK.C "sp|O95352|ATG7_HUMAN,tr|H7BZ92|H7BZ92_HUMAN,tr|H7C2R3|H7C2R3_HUMAN,tr|H7C2J8|H7C2J8_HUMAN" 4 1463.766 16.67 62828 21687 2 1463.764219 732.8903 Ubiquitin-like modifier-activating enzyme ATG7 OS=Homo sapiens OX=9606 GN=ATG7 PE=1 SV=1 4.21 3911.6 - 347988 - - - -1.2379 - 1.74 0.4 - 94.3 1 2 0 -0.0018 13 0 0 0 1.59E+06 9.51E+04 - - - 3.4164 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21689.21689.2 0.00051 13/24 K.QLLDSGLPSLLVR.S "sp|Q9NR09|BIRC6_HUMAN,tr|A0A3B3IUB9|A0A3B3IUB9_HUMAN" 2 1409.8242 4.07 62830 21689 2 1409.823943 705.9194 Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=BIRC6 PE=1 SV=2 5.84 3911.8 - 332953 - - - -0.1929 - 2.235 0.45 - 636.4 1 2 0 -0.0003 13 0 0 0 9.26E+05 2.28E+05 - - - 4.4287 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21690.21690.2 0.044 14-Sep K.ENLLDFIK.H "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 990.5386 2.32 62831 21690 2 990.53961 496.2766 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.37 3912 - 327552 - - - 1.0227 - 1.965 0.284 - 310.4 1 2 0 0.001 8 0 0 0 7.31E+07 3.15E+07 - - - 3.1756 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.21691.21691.3 0.0109 13/48 R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 -1 62832 21691 3 1448.790572 483.9374 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3912.1 - 281845 - - - 0.1974 - 2.187 0.255 - 238.4 1 2 0 0.0003 13 0 0 0 0.00E+00 0.00E+00 - - - 3.5046 0.9948 230117_WJC_METTL3_WT_vs_EV_F07.21693.21693.2 0.233 24-Aug K.NASILLEELDLEK.L "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1485.7926 2.36 62834 21693 2 1485.792221 743.9036 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4 3912.4 - 211292 - - - -0.282 - 1.538 0.166 - 133.6 1 2 0 -0.0004 13 0 0 0 1.13E+06 4.76E+05 - - - 1.3718 0.9779 230117_WJC_METTL3_WT_vs_EV_F07.21695.21695.2 0.0275 14-Aug R.NDFLELLR.R sp|O60870|KIN17_HUMAN 1 1018.5447 1.74 62835 21695 2 1018.541403 510.2796 DNA\RNA-binding protein KIN17 OS=Homo sapiens OX=9606 GN=KIN PE=1 SV=2 4.37 3912.7 - 106236 - - - -3.2812 - 1.265 0.269 - 194.1 1 2 0 -0.0033 8 0 0 0 3.32E+06 1.91E+06 - - - 1.7358 0.999 230117_WJC_METTL3_WT_vs_EV_F07.21696.21696.2 0.00787 14-Aug K.ENLLDFIK[136.11].H "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 998.5528 2.32 62836 21696 2 998.552418 500.2837 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.37 3912.7 - 302557 - - - -0.3795 - 1.828 0.299 - 257.2 1 2 0 -0.0004 8 0 0 0 7.31E+07 3.15E+07 - - - 3.0686 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21711.21711.2 0.00162 14-Aug R.ILEFFGLK.K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 965.5586 2.19 62849 21711 2 965.559362 483.7866 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3914.4 - 3.26E+06 - - - 0.784 - 1.631 0.393 - 173.1 1 2 0 0.0008 8 0 0 0 6.28E+07 2.87E+07 - - - 3.4188 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21713.21713.2 0.000235 18-Aug R.LSQSLLELWR.R "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1243.6925 1.46 62851 21713 2 1243.693691 622.8535 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 6 3914.5 - 1.56E+06 - - - 0.9801 - 1.836 0.451 - 268.6 1 2 0 0.0012 10 0 0 0 1.56E+07 1.07E+07 - - - 4.0677 0.9933 230117_WJC_METTL3_WT_vs_EV_F07.21717.21717.2 0.0636 14-May K.LYDFYLFK.C sp|Q2TAL8|QRIC1_HUMAN 1 1107.5641 1.74 62855 21717 2 1107.563388 554.7893 Transcriptional regulator QRICH1 OS=Homo sapiens OX=9606 GN=QRICH1 PE=1 SV=1 5.83 3914.8 - 669351 - - - -0.6284 - 0.903 0.353 - 57.8 1 2 0 -0.0007 8 0 0 0 1.77E+06 1.02E+06 - - - 1.3403 0.997 230117_WJC_METTL3_WT_vs_EV_F07.21722.21722.2 0.00748 14-Aug R.ILEFFGLK[136.11].K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 973.5728 2.19 62858 21722 2 973.570652 487.7937 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3915.4 - 6.76E+06 - - - -2.2114 - 1.745 0.337 - 166.8 1 2 0 -0.0022 8 0 0 0 6.27E+07 2.87E+07 - - - 3.2086 0.8914 230117_WJC_METTL3_WT_vs_EV_F07.21723.21723.2 0.000456 24-Sep K.VALVTASTDGIGF.A "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN" 5 1249.6554 - 62859 21723 2 1249.653812 625.835 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 3.8 3915.5 - 4.96E+06 - - - -1.2852 - 1.744 0.385 - 210.3 1 1 0 -0.0016 13 0 0 0 - - - - - 3.3116 0.9978 230117_WJC_METTL3_WT_vs_EV_F07.21724.21724.2 0.000119 22-Dec R.LLFPAVDDNLLK.F "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1356.7653 1.76 62860 21724 2 1356.762118 679.3899 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 4.21 3915.6 - 3.01E+06 - - - -2.3475 - 2.302 0.347 - 473.3 1 2 0 -0.0032 12 0 0 0 1.75E+07 9.95E+06 - - - 3.7968 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.21726.21726.2 2.37E-05 22-Nov R.LLFPAVDDNLLK[136.11].F "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1364.7795 1.75 62862 21726 2 1364.775357 683.397 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 4.21 3915.9 - 1.74E+06 - - - -3.0379 - 1.928 0.432 - 392.4 1 2 0 -0.0041 12 0 0 0 1.75E+07 1.00E+07 - - - 3.9578 1 230117_WJC_METTL3_WT_vs_EV_F07.21727.21727.2 3.35E-06 13/20 K.AFVDFLSDEIK.E sp|Q07021|C1QBP_HUMAN 1 1282.6445 1.4 62863 21727 2 1282.641037 642.3295 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.03 3916 - 1.51E+06 - - - -2.7147 - 2.259 0.603 - 552.6 1 2 0 -0.0035 11 0 0 0 9.38E+06 6.72E+06 - - - 5.6982 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.21733.21733.2 4.34E-06 20-Dec K.AFVDFLSDEIK[136.11].E sp|Q07021|C1QBP_HUMAN 1 1290.6587 1.4 62869 21733 2 1290.656098 646.3366 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.03 3916.8 - 944899 - - - -2.0307 - 2.185 0.434 - 489.9 1 2 0 -0.0026 11 0 0 0 9.38E+06 6.72E+06 - - - 4.3602 0.9834 230117_WJC_METTL3_WT_vs_EV_F07.21734.21734.2 0.0221 22-Aug R.LNMGEIETLDDY.- "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1411.6177 - 62870 21734 2 1411.612552 706.8161 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 3.43 3916.9 - 720384 - - - -3.6554 - 1.409 0.31 - 161.6 1 2 0 -0.0052 12 0 0 0 - - - - - 2.2312 1 230117_WJC_METTL3_WT_vs_EV_F07.21735.21735.2 6.21E-06 17/26 R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.14 62871 21735 2 1478.889648 740.4549 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3917 - 681512 - - - -3.7548 - 2.818 0.605 - 712.7 1 2 0 -0.0056 14 0 0 0 1.35E+08 1.18E+08 - - - 6.1076 1 230117_WJC_METTL3_WT_vs_EV_F07.21736.21736.2 1.18E-06 26-Dec R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.14 62872 21736 2 1470.877399 736.4478 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3917.2 - 612662 - - - -2.4489 - 2.537 0.61 - 309.8 1 2 0 -0.0036 14 0 0 0 1.35E+08 1.18E+08 - - - 5.8816 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21754.21754.2 0.793 13/24 R.LGPLLLDPSLAVR[166.11].E sp|Q7Z4Q2|HEAT3_HUMAN 1 1372.8318 0.86 62889 21754 2 1372.834263 687.4232 HEAT repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=HEATR3 PE=1 SV=2 5.84 3919.2 - 0 - - - 1.8254 - 2.266 0.328 - 455.3 1 2 0 0.0025 13 0 0 0 3.28E+06 3.83E+06 - - - 3.5623 1 230117_WJC_METTL3_WT_vs_EV_F07.21760.21760.2 1.30E-06 22-Dec R.YFPTQALNFAFK.D "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 1445.7343 1.14 62894 21760 2 1445.736668 723.8744 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.59 3919.9 - 4.76E+06 - - - 1.6123 - 2.109 0.531 - 463 1 2 0 0.0023 12 0 0 0 1.40E+08 1.23E+08 - - - 4.9256 1 230117_WJC_METTL3_WT_vs_EV_F07.21762.21762.2 1.72E-06 22-Dec K.WLAPDGLIFPDR[166.11].A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1408.7379 0.81 62895 21762 2 1408.738019 705.3762 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3920.1 - 2.84E+06 - - - 0.1157 - 2.573 0.558 - 526.6 1 2 0 0.0002 12 0 0 0 5.30E+07 6.54E+07 - - - 5.649 1 230117_WJC_METTL3_WT_vs_EV_F07.21763.21763.2 3.27E-05 22-Dec K.WLAPDGLIFPDR.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1398.7296 0.81 62896 21763 2 1398.729047 700.3721 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3920.1 - 1.80E+06 - - - -0.3853 - 2.668 0.523 - 549.5 1 2 0 -0.0005 12 0 0 0 5.30E+07 6.54E+07 - - - 5.4858 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21767.21767.2 0.000453 18-Aug R.IQFFAIEIAR.N sp|Q9BVG4|PBDC1_HUMAN 1 1206.6761 -1 62900 21767 2 1206.67711 604.3453 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 6 3920.5 - 0 - - - 0.842 - 1.895 0.454 - 193.7 1 2 0 0.001 10 0 0 0 0.00E+00 0.00E+00 - - - 4.1782 1 230117_WJC_METTL3_WT_vs_EV_F07.21768.21768.2 2.89E-06 14/26 R.LAQVSPELLLASVR.R sp|O43592|XPOT_HUMAN 1 1494.877 -1 62901 21768 2 1494.874344 748.4458 Exportin-T OS=Homo sapiens OX=9606 GN=XPOT PE=1 SV=2 6 3920.5 - 140882 - - - -1.7627 - 2.706 0.472 - 636.5 1 2 0 -0.0026 14 0 0 0 0.00E+00 0.00E+00 - - - 5.0245 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.21770.21770.2 0.0144 18-Aug R.SLGPVELLLR[166.11].G "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1105.6735 2.23 62903 21770 2 1105.674575 553.844 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.72 3920.6 - 154448 - - - 1.0039 - 1.759 0.328 - 206.7 1 2 0 0.0011 10 0 0 0 8.95E+06 4.01E+06 - - - 3.0396 1 230117_WJC_METTL3_WT_vs_EV_F07.21772.21772.2 5.40E-08 14/30 K.LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1793.9075 0.92 62905 21772 2 1793.905016 897.961 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3920.8 - 0 - - - -1.3847 - 2.907 0.606 - 480.6 1 2 0 -0.0025 16 0 0 0 1.45E+07 1.57E+07 - - - 6.1397 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21773.21773.2 0.00112 20-Sep K.LDTSQWPLLLK[136.11].N "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1320.7533 0.62 62906 21773 2 1320.754609 661.3839 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 5.84 3920.9 - 0 - - - 1.0002 - 2.174 0.388 - 325.4 1 2 0 0.0013 11 0 0 0 4.69E+06 7.56E+06 - - - 4.0072 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.21774.21774.2 4.04E-05 28-Sep R.ELALALQEALEPAVR.L sp|Q5RKV6|EXOS6_HUMAN 1 1621.9039 -1 62907 21774 2 1621.902224 811.9592 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 4.25 3921 - 0 - - - -1.0469 - 2.039 0.352 - 220.4 1 2 0 -0.0017 15 0 0 0 0.00E+00 0.00E+00 - - - 3.392 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21777.21777.2 1.99E-05 26-Sep K.TYVLNPLAPEFIPR[166.11].A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1638.9009 -1 62910 21777 2 1638.901256 820.4577 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.66 3921.2 - 119711 - - - 0.2178 - 2.023 0.473 - 239.5 1 2 0 0.0004 14 0 0 0 0.00E+00 0.00E+00 - - - 4.3026 0.9322 230117_WJC_METTL3_WT_vs_EV_F07.21778.21778.2 2.96 20-Jun K.ELGEYFLFDPK.K "sp|O60610|DIAP1_HUMAN,tr|A0A2R8Y5N1|A0A2R8Y5N1_HUMAN,tr|A0A140T8Z0|A0A140T8Z0_HUMAN,tr|A0A0G2JH68|A0A0G2JH68_HUMAN,tr|H9KV28|H9KV28_HUMAN" 5 1356.6602 2.88 62911 21778 2 1356.659331 679.3374 Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2 4.14 3921.3 - 205184 - - - -0.6177 - 1.035 0.073 - 59 1 2 0 -0.0008 11 0 0 0 2.63E+06 9.13E+05 - - - -0.327 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21781.21781.3 0.000547 15/40 K.LPLGLLLHPFR.D sp|O95487|SC24B_HUMAN 1 1274.7863 1.59 62914 21781 3 1274.784884 425.936 Protein transport protein Sec24B OS=Homo sapiens OX=9606 GN=SEC24B PE=1 SV=2 9.76 3921.6 - 0 - - - -1.121 - 2.955 0.29 - 414.4 1 2 0 -0.0014 11 0 0 0 1.32E+06 8.28E+05 - - - 4.8509 0.9968 230117_WJC_METTL3_WT_vs_EV_F07.21784.21784.2 0.0154 20-Oct K.LDTSQWPLLLK.N "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1312.7391 0.62 62916 21784 2 1312.74538 657.3768 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 5.84 3922.1 - 364158 - - - 4.793 - 2.234 0.264 - 441.7 1 2 0 0.0063 11 0 0 0 4.61E+06 7.48E+06 - - - 3.1634 1 230117_WJC_METTL3_WT_vs_EV_F07.21786.21786.3 2.05E-08 20/52 R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.2 62918 21786 3 1470.883573 491.3009 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3922.3 - 3.59E+06 - - - 1.7486 - 2.991 0.552 - 470.9 1 2 0 0.0026 14 0 0 0 1.40E+07 1.16E+07 - - - 7.6052 1 230117_WJC_METTL3_WT_vs_EV_F07.21787.21787.3 3.26E-06 22/52 R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.2 62919 21787 3 1478.896782 493.9723 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3922.4 - 3.52E+06 - - - 1.069 - 2.986 0.583 - 636.7 1 2 0 0.0016 14 0 0 0 1.40E+07 1.16E+07 - - - 7.9466 1 230117_WJC_METTL3_WT_vs_EV_F07.21790.21790.2 2.49E-06 19/30 K.LFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1783.8992 0.92 62922 21790 2 1783.899228 892.9569 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3922.8 - 2.34E+06 - - - -0.0011 - 3.369 0.606 - 1102 1 2 0 0 16 0 0 0 1.45E+07 1.57E+07 - - - 6.5031 1 230117_WJC_METTL3_WT_vs_EV_F07.21791.21791.2 7.70E-05 13/20 Q.AFADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1170.7012 5.01 62923 21791 2 1170.703261 586.3579 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3923 - 1.55E+06 - - - 1.7212 - 2.229 0.483 - 415.6 1 1 0 0.002 11 0 0 0 4.78E+06 9.55E+05 - - - 4.7762 1 230117_WJC_METTL3_WT_vs_EV_F07.21792.21792.2 7.93E-09 14/26 K.TYVLNPLAPEFIPR.A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1628.8926 2.69 62924 21792 2 1628.892523 815.4536 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.66 3923.1 - 1.50E+06 - - - -0.0651 - 2.841 0.62 - 590 1 2 0 -0.0001 14 0 0 0 5.43E+06 2.02E+06 - - - 6.2405 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21793.21793.2 0.000706 22-Dec R.FSPIPFPPLSYK.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1391.7489 4.55 62925 21793 2 1391.752163 696.8817 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3923.2 - 1.20E+06 - - - 2.3266 - 2.015 0.364 - 287.1 1 2 0 0.0032 12 0 0 0 1.02E+07 2.25E+06 - - - 3.5719 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21798.21798.2 0.00137 18-Oct R.SLGPVELLLR.G "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1095.6652 2.23 62930 21798 2 1095.666802 548.8399 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.72 3923.9 - 631289 - - - 1.4667 - 1.669 0.39 - 346.2 1 2 0 0.0016 10 0 0 0 8.95E+06 4.01E+06 - - - 3.3508 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.21800.21800.2 0.000989 16-Jul R.GYPTLLLFR.G sp|Q8NBS9|TXND5_HUMAN 1 1078.6175 1.6 62932 21800 2 1078.617467 540.316 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 8.75 3924.1 - 571456 - - - -0.0454 - 1.663 0.386 - 209.2 1 2 0 0 9 0 0 0 8.42E+06 5.27E+06 - - - 3.3635 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21801.21801.2 0.00265 13/18 R.VVTDLISLIR.Q sp|P38432|COIL_HUMAN 1 1127.6914 1.2 62933 21801 2 1127.693117 564.853 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3924.3 - 491807 - - - 1.5137 - 2.253 0.357 - 669.2 1 2 0 0.0017 10 0 0 0 8.79E+06 7.35E+06 - - - 3.9445 1 230117_WJC_METTL3_WT_vs_EV_F07.21802.21802.2 1.94E-07 13/26 R.VLSFPGGSLLLAGR.S sp|Q8NCM8|DYHC2_HUMAN 1 1385.8031 -1 62934 21802 2 1385.80494 693.9088 Cytoplasmic dynein 2 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC2H1 PE=1 SV=4 9.72 3924.4 - 388500 - - - 1.3386 - 2.496 0.582 - 328.4 1 2 0 0.0019 14 0 0 0 0.00E+00 0.00E+00 - - - 5.6344 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21807.21807.2 0.00157 14/18 R.VVTDLISLIR[166.11].Q sp|P38432|COIL_HUMAN 1 1137.6997 1.2 62938 21807 2 1137.701727 569.8571 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3924.9 - 4.41E+06 - - - 1.7992 - 2.332 0.391 - 736.2 1 2 0 0.002 10 0 0 0 8.79E+06 7.35E+06 - - - 4.2918 0.9975 230117_WJC_METTL3_WT_vs_EV_F07.21809.21809.2 0.281 16-Jul R.FYELLVTGR.Y "sp|Q9UPS6|SET1B_HUMAN,tr|A0A0A0MQV9|A0A0A0MQV9_HUMAN" 2 1096.5917 4.85 62940 21809 2 1096.593961 549.3031 Histone-lysine N-methyltransferase SETD1B OS=Homo sapiens OX=9606 GN=SETD1B PE=1 SV=3 6 3925 - 2.46E+06 - - - 2.0655 - 1.438 0.208 - 165.9 1 2 0 0.0023 9 0 0 0 5.40E+06 1.11E+06 - - - 1.6275 0.9627 230117_WJC_METTL3_WT_vs_EV_F07.21810.21810.2 0.14 16-Sep N.VLIIGELLK.Q "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 996.6583 -1 62941 21810 2 996.659887 499.3364 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.97 3925.2 - 2.16E+06 - - - 1.5733 - 1.729 0.359 - 243.5 1 1 0 0.0016 9 0 0 0 0.00E+00 0.00E+00 - - - 3.2762 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21812.21812.2 0.000146 20-Oct R.LFEFAGYDVLR[166.11].L sp|P54136|SYRC_HUMAN 1 1338.6848 -1 62943 21812 2 1338.687858 670.3497 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3925.4 - 1.74E+06 - - - 2.3157 - 2.144 0.468 - 272 1 2 0 0.0031 11 0 0 0 0.00E+00 0.00E+00 - - - 4.5599 1 230117_WJC_METTL3_WT_vs_EV_F07.21813.21813.2 0.00044 18-Oct K.FLDVLELAEK.F "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1175.6438 0.81 62944 21813 2 1175.645422 588.8292 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.14 3925.5 - 1.39E+06 - - - 1.3873 - 2.289 0.492 - 266.7 1 2 0 0.0016 10 0 0 0 3.77E+06 4.66E+06 - - - 4.9859 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.21816.21816.2 0.00408 16-Jul R.GYPTLLLFR[166.11].G sp|Q8NBS9|TXND5_HUMAN 1 1088.6258 1.68 62947 21816 2 1088.629223 545.3202 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 8.75 3925.9 - 1.07E+06 - - - 3.1572 - 1.507 0.447 - 189.9 1 2 0 0.0034 9 0 0 0 8.35E+06 4.98E+06 - - - 3.528 0.9857 230117_WJC_METTL3_WT_vs_EV_F07.21817.21817.3 0.00225 Dec-40 K.IRFLILPDMLK.N sp|P62318|SMD3_HUMAN 1 1357.8156 1.27 62948 21817 3 1357.817825 453.6125 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 8.75 3926.1 - 985019 - - - 1.6652 - 2.321 0.338 - 271.5 1 2 1 0.0023 11 0 0 0 1.64E+06 1.29E+06 - - - 4.6997 0.9541 230117_WJC_METTL3_WT_vs_EV_F07.21819.21819.3 0.0214 Nov-40 K.IR[166.11]FLILPDMLK[136.11].N sp|P62318|SMD3_HUMAN 1 1375.838 -1 62950 21819 3 1375.839921 459.62 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 8.75 3926.3 - 732847 - - - 1.3715 - 1.641 0.324 - 142.4 1 2 1 0.0019 11 0 0 0 0.00E+00 0.00E+00 - - - 3.5588 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21821.21821.2 0.131 18-Nov K.FLDVLELAEK[136.11].F "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1183.658 0.81 62952 21821 2 1183.659998 592.8363 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.14 3926.5 - 635812 - - - 1.6956 - 2.004 0.335 - 295.1 1 2 0 0.002 10 0 0 0 3.77E+06 4.66E+06 - - - 3.455 1 230117_WJC_METTL3_WT_vs_EV_F07.21827.21827.2 4.81E-05 13/20 R.LFEFAGYDVLR.L sp|P54136|SYRC_HUMAN 1 1328.6765 -1 62957 21827 2 1328.681441 665.3455 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3927.4 - 5.27E+06 - - - 3.7278 - 2.556 0.541 - 692.9 1 2 0 0.005 11 0 0 0 0.00E+00 0.00E+00 - - - 5.574 1 230117_WJC_METTL3_WT_vs_EV_F07.21828.21828.2 0.000109 18-Dec R.DAVLLLFANK.Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1102.6386 -1 62958 21828 2 1102.643101 552.3266 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3927.5 - 3.88E+06 - - - 4.0403 - 2.489 0.485 - 757.4 1 2 0 0.0045 10 0 0 0 0.00E+00 0.00E+00 - - - 5.1671 1 230117_WJC_METTL3_WT_vs_EV_F07.21830.21830.2 0.000228 18-Nov R.DAVLLLFANK[136.11].Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1110.6528 -1 62960 21830 2 1110.657037 556.3337 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3927.7 - 1.83E+06 - - - 3.7735 - 2.404 0.45 - 549 1 2 0 0.0042 10 0 0 0 0.00E+00 0.00E+00 - - - 4.8117 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.21831.21831.2 4.89E-06 16-Oct K.APWELLELR[166.11].V "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A6Q8PF15|A0A6Q8PF15_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN,tr|A0A6Q8PFC1|A0A6Q8PFC1_HUMAN" 6 1135.6265 1.07 62961 21831 2 1135.630291 568.8205 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.53 3927.8 - 1.31E+06 - - - 3.325 - 2.06 0.457 - 545.7 1 2 0 0.0038 9 0 0 0 4.46E+06 4.19E+06 - - - 4.506 1 230117_WJC_METTL3_WT_vs_EV_F07.21839.21839.2 6.32E-08 15/30 R.IIGATDSSGELMFLMK.W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1711.8525 -1 62969 21839 2 1711.854514 856.9335 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3928.9 - 695798 - - - 1.1882 - 3.408 0.617 - 474.2 1 2 0 0.002 16 0 0 0 0.00E+00 0.00E+00 - - - 6.612 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.21848.21848.2 0.00123 20-Nov R.SVVTVIDVFYK.Y sp|Q5D862|FILA2_HUMAN 1 1268.7016 19.79 62977 21848 2 1268.706888 635.3581 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 5.55 3929.9 - 7.25E+06 - - - 4.1365 - 2.386 0.393 - 368.7 1 2 0 0.0052 11 0 0 0 1.93E+07 9.73E+05 - - - 4.2946 1 230117_WJC_METTL3_WT_vs_EV_F07.21849.21849.2 1.61E-05 13/20 K.VTDLLGGLFSK[136.11].T "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1156.6583 -1 62978 21849 2 1156.662501 579.3364 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.81 3930 - 6.45E+06 - - - 3.6104 - 2.864 0.453 - 925.9 1 2 0 0.0042 11 0 0 0 0.00E+00 0.00E+00 - - - 5.232 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.21851.21851.2 6.90E-05 20-Nov R.FLEEFITPIVK.V "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 1334.7486 1.55 62980 21851 2 1334.752965 668.3816 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.53 3930.2 - 2.18E+06 - - - 3.2778 - 2.03 0.45 - 293.6 1 2 0 0.0044 11 0 0 0 6.50E+06 4.19E+06 - - - 4.2787 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.21852.21852.2 0.000607 18-Oct R.DALLLIFANK.Q "sp|P36406|TRI23_HUMAN,sp|P62330|ARF6_HUMAN" 2 1116.6543 1.58 62981 21852 2 1116.658479 559.3344 E3 ubiquitin-protein ligase TRIM23 OS=Homo sapiens OX=9606 GN=TRIM23 PE=1 SV=1 5.84 3930.4 - 1.40E+06 - - - 3.746 - 2.321 0.432 - 282.7 1 2 0 0.0042 10 0 0 0 2.94E+06 1.87E+06 - - - 4.5807 0.999 230117_WJC_METTL3_WT_vs_EV_F07.21856.21856.2 0.0163 14-Aug R.AAFLNFFR.D sp|Q5JTZ9|SYAM_HUMAN 1 984.5181 2.48 62985 21856 2 984.520662 493.2663 "Alanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=AARS2 PE=1 SV=1" 9.79 3930.9 - 1.06E+06 - - - 2.5647 - 1.509 0.344 - 247.5 1 2 0 0.0025 8 0 0 0 2.01E+06 8.07E+05 - - - 2.8219 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.21859.21859.2 2.87E-05 20-Jul R.VINQMLEFAFR.Y "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 1366.7067 2.28 62988 21859 2 1366.713415 684.3606 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 5.97 3931.3 - 985740 - - - 4.8825 - 1.931 0.457 - 163.4 1 2 0 0.0067 11 0 0 0 2.08E+06 9.12E+05 - - - 4.1945 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.21860.21860.2 5.06 18-Oct R.DALLLIFANK[136.11].Q "sp|P36406|TRI23_HUMAN,sp|P62330|ARF6_HUMAN" 2 1124.6685 1.58 62989 21860 2 1124.672983 563.3415 E3 ubiquitin-protein ligase TRIM23 OS=Homo sapiens OX=9606 GN=TRIM23 PE=1 SV=1 5.84 3931.4 - 834265 - - - 3.9896 - 2.203 0.338 - 243.3 1 2 0 0.0045 10 0 0 0 2.94E+06 1.87E+06 - - - 3.7407 0.9683 230117_WJC_METTL3_WT_vs_EV_F07.21864.21864.2 0.00826 20-Sep R.VINQMLEFAFR[166.11].Y "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 1376.715 -1 62993 21864 2 1376.726382 689.3648 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 5.97 3931.9 - 544777 - - - 8.2588 - 1.605 0.334 - 206.2 1 2 0 0.0114 11 0 0 0 0.00E+00 0.00E+00 - - - 2.7843 1 230117_WJC_METTL3_WT_vs_EV_F07.21867.21867.2 7.84E-06 30-Dec R.IIGATDSSGELMFLMK[136.11].W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1719.8667 -1 62995 21867 2 1719.869653 860.9406 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3932.4 - 91032.4 - - - 1.7286 - 2.576 0.571 - 253 1 2 0 0.003 16 0 0 0 0.00E+00 0.00E+00 - - - 5.5838 1 230117_WJC_METTL3_WT_vs_EV_F07.21869.21869.2 0.000157 20-Nov K.YPSPFFVFGEK[136.11].L sp|Q08211|DHX9_HUMAN 1 1324.6583 0.91 62997 21869 2 1324.661146 663.3364 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3932.6 - 4.64E+06 - - - 2.1296 - 2.188 0.478 - 453.8 1 2 0 0.0028 11 0 0 0 3.13E+07 3.43E+07 - - - 4.6888 1 230117_WJC_METTL3_WT_vs_EV_F07.21870.21870.2 3.18E-08 20-Dec K.YPSPFFVFGEK.L sp|Q08211|DHX9_HUMAN 1 1316.6441 0.9 62998 21870 2 1316.647329 659.3293 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3932.6 - 3.96E+06 - - - 2.4335 - 2.361 0.593 - 656.1 1 2 0 0.0032 11 0 0 0 3.08E+07 3.43E+07 - - - 5.7439 1 230117_WJC_METTL3_WT_vs_EV_F07.21873.21873.2 3.79E-08 22-Nov R.FSTFFDDAPVFR.L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1447.6772 -1 63001 21873 2 1447.679817 724.8459 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3932.9 - 1.70E+06 - - - 1.7967 - 2.289 0.632 - 411 1 2 0 0.0026 12 0 0 0 0.00E+00 0.00E+00 - - - 5.887 1 230117_WJC_METTL3_WT_vs_EV_F07.21874.21874.2 8.35E-10 20/30 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 -1 63002 21874 2 1807.92644 904.9689 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3933 - 1.09E+06 - - - 1.8198 - 3.401 0.601 - 1196.8 1 2 0 0.0033 16 0 0 0 0.00E+00 0.00E+00 - - - 6.4884 1 230117_WJC_METTL3_WT_vs_EV_F07.21875.21875.2 6.36E-06 13/22 R.FSTFFDDAPVFR[166.11].L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1457.6855 -1 63003 21875 2 1457.69056 729.85 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3933.1 - 906958 - - - 3.4809 - 2.54 0.572 - 511.3 1 2 0 0.0051 12 0 0 0 0.00E+00 0.00E+00 - - - 5.7169 1 230117_WJC_METTL3_WT_vs_EV_F07.21876.21876.2 9.57E-10 21/30 K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 -1 63004 21876 2 1797.918851 899.9647 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3933.3 - 865744 - - - 2.2087 - 3.668 0.643 - 1517.1 1 2 0 0.004 16 0 0 0 0.00E+00 0.00E+00 - - - 6.9842 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21879.21879.2 0.00197 14-Sep R.GFGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 921.5204 1.15 63007 21879 2 921.522591 461.7675 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3933.6 - 632464 - - - 2.4047 - 1.505 0.465 - 240.1 1 2 0 0.0022 8 0 0 0 9.23E+07 8.05E+07 - - - 3.7077 0.9407 230117_WJC_METTL3_WT_vs_EV_F07.21880.21880.2 0.000599 20-Dec R.IFGLLMGTLQK.F sp|Q9H307|PININ_HUMAN 1 1219.6999 1.22 63008 21880 2 1220.702026 610.8572 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3933.8 - 524823 - - - 821.6448 - 2.349 0.469 - 402.2 1 2 0 1.0022 11 0 0 0 9.50E+06 7.82E+06 - - - 4.5006 0.999 230117_WJC_METTL3_WT_vs_EV_F07.21883.21883.2 0.34 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 63011 21883 2 1603.76823 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3934.2 - 320632 - - - 2.675 - 1.729 0.326 - 191.2 1 2 0 0.0043 12 0 0 0 4.67E+06 0.00E+00 - - - 2.8882 1 230117_WJC_METTL3_WT_vs_EV_F07.21890.21890.2 1.46E-05 20-Dec R.IFGLLMGTLQK[136.11].F sp|Q9H307|PININ_HUMAN 1 1227.7141 1.22 63017 21890 2 1227.722447 614.8643 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3935 - 3.16E+06 - - - 6.8265 - 2.286 0.488 - 408.8 1 2 0 0.0084 11 0 0 0 9.50E+06 7.82E+06 - - - 4.8794 1 230117_WJC_METTL3_WT_vs_EV_F07.21891.21891.2 7.54E-05 20-Dec R.IFGLLMGTLQK.F sp|Q9H307|PININ_HUMAN 1 1219.6999 1.22 63018 21891 2 1219.708508 610.8572 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3935.2 - 2.96E+06 - - - 7.0853 - 2.333 0.528 - 435.7 1 2 0 0.0086 11 0 0 0 9.50E+06 7.82E+06 - - - 5.2298 0.9956 230117_WJC_METTL3_WT_vs_EV_F07.21892.21892.2 0.00172 14-Sep R.GFGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 913.5062 1.15 63019 21892 2 913.511533 457.7604 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3935.2 - 2.94E+06 - - - 5.8653 - 1.53 0.469 - 249.6 1 2 0 0.0054 8 0 0 0 9.23E+07 8.05E+07 - - - 3.7859 1 230117_WJC_METTL3_WT_vs_EV_F07.21893.21893.2 0.000234 14/24 N.IVGLVGVDQFLVK.T sp|P13639|EF2_HUMAN 1 1385.8282 -1 63020 21893 2 1385.838004 693.9214 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3935.3 - 2.03E+06 - - - 7.047 - 2.763 0.541 - 552.5 1 1 0 0.0098 13 0 0 0 0.00E+00 0.00E+00 - - - 5.6422 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.21894.21894.3 1.28E-05 Dec-60 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 -1 63021 21894 3 1807.93603 603.6483 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3935.5 - 1.36E+06 - - - 7.1242 - 2.6 0.497 - 190.6 1 2 0 0.0129 16 0 0 0 0.00E+00 0.00E+00 - - - 6.5292 1 230117_WJC_METTL3_WT_vs_EV_F07.21895.21895.2 1.34E-05 14/24 N.IVGLVGVDQFLVK[136.11].T sp|P13639|EF2_HUMAN 1 1393.8424 -1 63022 21895 2 1393.851802 697.9285 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3935.6 - 952299 - - - 6.7181 - 2.472 0.506 - 517.4 1 1 0 0.0094 13 0 0 0 0.00E+00 0.00E+00 - - - 5.0982 0.9938 230117_WJC_METTL3_WT_vs_EV_F07.21896.21896.3 0.00318 Nov-56 K.GLAPDLPEDLYHLIK[136.11].K "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1700.9229 -1 63023 21896 3 1700.935009 567.9816 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 4.54 3935.7 - 866953 - - - 7.135 - 2.178 0.35 - 120.6 1 2 0 0.0121 15 0 0 0 0.00E+00 0.00E+00 - - - 4.4699 1 230117_WJC_METTL3_WT_vs_EV_F07.21900.21900.2 8.66E-09 14/30 R.IMEGPAFNFLDAPAVR.V sp|P11177|ODPB_HUMAN 1 1746.8763 -1 63027 21900 2 1746.887624 874.4454 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 4.37 3936.2 - 555655 - - - 6.467 - 3.035 0.601 - 661.8 1 2 0 0.0113 16 0 0 0 0.00E+00 0.00E+00 - - - 6.2059 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.21901.21901.2 4.20E-06 15/30 K.LFIGGLSFETTDDSLR.E "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1769.8836 -1 63028 21901 2 1769.891458 885.9491 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.03 3936.4 - 548862 - - - 4.4511 - 2.057 0.466 - 574.6 1 2 0 0.0079 16 0 0 0 0.00E+00 0.00E+00 - - - 4.2536 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.21902.21902.2 2.48E-05 30-Oct K.LFIGGLSFETTDDSLR[166.11].E "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1779.8918 -1 63029 21902 2 1779.899989 890.9532 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.03 3936.5 - 498799 - - - 4.5727 - 2.148 0.452 - 230.7 1 2 0 0.0081 16 0 0 0 0.00E+00 0.00E+00 - - - 4.2566 1 230117_WJC_METTL3_WT_vs_EV_F07.21911.21911.3 1.58E-06 16/60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 -1 63037 21911 3 1796.007107 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3937.6 - 1.19E+06 - - - 1.5273 - 3.154 0.495 - 441 1 2 0 0.0027 16 0 0 0 0.00E+00 0.00E+00 - - - 7.0053 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.21912.21912.2 0.359 18-Sep K.FLLLQGLVEK.E "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 1158.7012 -1 63038 21912 2 1158.702327 580.3579 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 6 3937.7 - 851139 - - - 0.9329 - 1.838 0.306 - 216.5 1 2 0 0.0011 10 0 0 0 0.00E+00 0.00E+00 - - - 2.9998 0.9763 230117_WJC_METTL3_WT_vs_EV_F07.21913.21913.2 0.00752 12-Sep G.FGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 856.4847 -1 63039 21913 2 856.485234 429.2496 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3937.8 - 627168 - - - 0.6106 - 1.738 0.485 - 228.7 1 1 0 0.0005 7 0 0 0 0.00E+00 0.00E+00 - - - 4.3744 0.9899 230117_WJC_METTL3_WT_vs_EV_F07.21914.21914.2 0.141 12-Jul K.ELFSFFR.D "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 944.4756 -1 63040 21914 2 944.474445 473.2451 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6.1 3937.9 - 549769 - - - -1.2261 - 1.386 0.167 - 190 1 2 0 -0.0012 7 0 0 0 0.00E+00 0.00E+00 - - - 1.3084 0.8751 230117_WJC_METTL3_WT_vs_EV_F07.21915.21915.2 11 22-Aug K.YDNMAELFAVVK.T "sp|Q9UK41|VPS28_HUMAN,tr|E9PR04|E9PR04_HUMAN,tr|E9PQR7|E9PQR7_HUMAN,tr|E9PM90|E9PM90_HUMAN" 4 1398.6853 -1 63041 21915 2 1398.68614 700.3499 Vacuolar protein sorting-associated protein 28 homolog OS=Homo sapiens OX=9606 GN=VPS28 PE=1 SV=1 4.37 3938.1 - 487648 - - - 0.5734 - 0.931 0.003 - 64.9 1 2 0 0.0008 12 0 0 0 0.00E+00 0.00E+00 - - - -1.1252 0.977 230117_WJC_METTL3_WT_vs_EV_F07.21916.21916.2 0.000153 12-Jul G.FGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 864.4989 -1 63042 21916 2 864.499488 433.2567 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3938.2 - 470846 - - - 0.6674 - 1.596 0.526 - 119.5 1 1 0 0.0006 7 0 0 0 0.00E+00 0.00E+00 - - - 4.4072 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.21920.21920.2 0.0131 18-Oct K.IATLISSFLK.E "sp|O95394|AGM1_HUMAN,tr|A0A494C1E2|A0A494C1E2_HUMAN,tr|J3KN95|J3KN95_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C1Q4|A0A494C1Q4_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|A0A087WT27|A0A087WT27_HUMAN" 7 1091.659 -1 63046 21920 2 1091.658482 546.8368 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 8.75 3938.7 - 327093 - - - -0.5176 - 1.49 0.354 - 182 1 2 0 -0.0006 10 0 0 0 0.00E+00 0.00E+00 - - - 2.7686 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.21932.21932.3 0.082 Aug-44 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 -1 63057 21932 3 1459.793084 487.6047 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3940.1 - 6.05E+06 - - - 0.5741 - 1.822 0.242 - 160.2 1 2 0 0.0008 12 0 0 0 0.00E+00 0.00E+00 - - - 2.9008 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21933.21933.2 0.497 20-Dec K.LALGIPLPELR.N "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1190.7387 -1 63058 21933 2 1190.739786 596.3766 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3940.2 - 3.59E+06 - - - 0.9171 - 2.547 0.286 - 424.5 1 2 0 0.0011 11 0 0 0 0.00E+00 0.00E+00 - - - 3.6822 0.9981 230117_WJC_METTL3_WT_vs_EV_F07.21939.21939.2 0.248 14/20 K.LALGIPLPELR[166.11].N "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1200.747 -1 63064 21939 2 1200.74803 601.3808 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3940.6 - 1.42E+06 - - - 0.8878 - 2.048 0.113 - 646.1 1 2 0 0.0011 11 0 0 0 0.00E+00 0.00E+00 - - - 1.8146 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.21941.21941.2 0.0538 20-Dec K.AIVEFLSNLAR.H sp|Q13112|CAF1B_HUMAN 1 1231.6925 -1 63066 21941 2 1231.693338 616.8535 Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1 6.05 3940.8 - 1.03E+06 - - - 0.7031 - 2.331 0.256 - 637 1 2 0 0.0009 11 0 0 0 0.00E+00 0.00E+00 - - - 3.221 0.9892 230117_WJC_METTL3_WT_vs_EV_F07.21943.21943.2 0.476 20-Sep K.AIVEFLSNLAR[166.11].H sp|Q13112|CAF1B_HUMAN 1 1241.7007 -1 63068 21943 2 1241.705305 621.8576 Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1 6.05 3941 - 731812 - - - 3.6748 - 1.403 0.165 - 253.4 1 2 0 0.0046 11 0 0 0 0.00E+00 0.00E+00 - - - 1.1743 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.21946.21946.2 0.00168 20-Sep K.VVLPTFILEPR.S "sp|Q9BZF1|OSBL8_HUMAN,tr|F8VUA7|F8VUA7_HUMAN,tr|F8VQX7|F8VQX7_HUMAN" 3 1282.7649 -1 63071 21946 2 1282.765087 642.3897 Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3 5.97 3941.3 - 566543 - - - 0.1388 - 2.069 0.431 - 321.7 1 2 0 0.0002 11 0 0 0 0.00E+00 0.00E+00 - - - 4.1912 1 230117_WJC_METTL3_WT_vs_EV_F07.21947.21947.2 8.26E-05 16/28 R.VLAFLSSVAGDALTR[166.11].H sp|Q92616|GCN1_HUMAN 1 1528.8489 -1 63072 21947 2 1528.850114 765.4317 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.81 3941.4 - 511110 - - - 0.8183 - 3.128 0.601 - 924.3 1 2 0 0.0013 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2833 1 230117_WJC_METTL3_WT_vs_EV_F07.21948.21948.2 1.24E-06 18-Nov K.ADLTALFLPR[166.11].Q sp|Q13045|FLII_HUMAN 1 1125.6422 1.76 63073 21948 2 1125.643622 563.8284 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.88 3941.5 - 503328 - - - 1.2944 - 2.691 0.534 - 372.1 1 2 0 0.0015 10 0 0 0 4.02E+06 2.28E+06 - - - 5.7478 1 230117_WJC_METTL3_WT_vs_EV_F07.21949.21949.2 1.11E-06 13/20 K.TPVLFDIYEIK.E sp|P50995|ANX11_HUMAN 1 1336.7279 -1 63074 21949 2 1337.740112 669.3712 Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1 4.37 3941.7 - 458506 - - - 757.2648 - 2.804 0.58 - 912.6 1 2 0 1.0123 11 0 0 0 0.00E+00 0.00E+00 - - - 5.7963 1 230117_WJC_METTL3_WT_vs_EV_F07.21954.21954.2 7.95E-07 16/26 K.LYSPSQIGAFVLMK.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1552.8323 4.18 63078 21954 2 1552.838171 777.4234 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3942.4 - 1.80E+06 - - - 3.757 - 2.976 0.632 - 849.3 1 2 0 0.0058 14 0 0 0 1.88E+07 4.51E+06 - - - 6.4439 0.9938 230117_WJC_METTL3_WT_vs_EV_F07.21955.21955.2 1.73E-05 16-Oct R.NLPFDFTWK.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1166.576 2.6 63079 21955 2 1166.582806 584.2953 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3942.4 - 1.70E+06 - - - 5.7947 - 1.742 0.342 - 285 1 2 0 0.0068 9 0 0 0 1.02E+08 3.92E+07 - - - 3.1706 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.21960.21960.2 0.000111 14-Jul R.DFC[160.03]FFTIK.F "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1076.5001 -1 63084 21960 2 1076.505453 539.2573 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.83 3943.1 - 635610 - - - 4.9689 - 1.56 0.47 - 160.1 1 2 0 0.0053 8 0 0 0 0.00E+00 0.00E+00 - - - 3.8519 0.9979 230117_WJC_METTL3_WT_vs_EV_F07.21961.21961.2 0.000359 14-Aug R.DFC[160.03]FFTIK[136.11].F "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1084.5143 -1 63085 21961 2 1084.51926 543.2644 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.83 3943.2 - 603172 - - - 4.5698 - 1.427 0.463 - 166.2 1 2 0 0.005 8 0 0 0 0.00E+00 0.00E+00 - - - 3.5316 0.9895 230117_WJC_METTL3_WT_vs_EV_F07.21963.21963.2 0.000661 16-Nov R.DILALMEVK.M sp|Q96EK4|THA11_HUMAN 1 1030.5733 2.87 63087 21963 2 1030.579656 516.2939 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 4.37 3943.5 - 515109 - - - 6.1985 - 2.108 0.222 - 349.6 1 2 0 0.0064 9 0 0 0 1.41E+06 4.91E+05 - - - 2.8362 1 230117_WJC_METTL3_WT_vs_EV_F07.21968.21968.2 2.31E-07 13/26 K.LYSPSQIGAFVLMK[136.11].M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1560.8465 -1 63092 21968 2 1560.853214 781.4305 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3944.1 - 394884 - - - 4.2778 - 2.7 0.565 - 552.8 1 2 0 0.0067 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7045 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.21970.21970.2 0.048 14-Sep K.ISLIQIFR[166.11].A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 998.6152 -1 63094 21970 2 998.619781 500.3149 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.75 3944.4 - 351115 - - - 4.5653 - 1.932 0.294 - 255.8 1 2 0 0.0046 8 0 0 0 0.00E+00 0.00E+00 - - - 3.1972 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21974.21974.2 0.0636 20-Sep K.DFAPVIVEAFK.H "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1234.6598 -1 63097 21974 2 1234.661738 618.3372 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.37 3944.7 - 3.38E+06 - - - 1.5899 - 1.927 0.445 - 223.2 1 2 0 0.002 11 0 0 0 0.00E+00 0.00E+00 - - - 4.1017 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.21977.21977.2 0.0025 16-May R.NLPFDFTWK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1174.5902 2.6 63100 21977 2 1174.591611 588.3024 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3944.8 - 2.51E+06 - - - 1.1621 - 1.278 0.348 - 59 1 2 0 0.0014 9 0 0 0 1.02E+08 3.92E+07 - - - 2.3206 1 230117_WJC_METTL3_WT_vs_EV_F07.21978.21978.2 4.61E-07 18/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 4.43 63101 21978 2 1591.947416 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3944.9 - 2.43E+06 - - - 1.5183 - 2.899 0.563 - 735.1 1 2 0 0.0024 15 0 0 0 1.03E+08 2.34E+07 - - - 5.8154 0.9904 230117_WJC_METTL3_WT_vs_EV_F07.21982.21982.2 0.887 22-May R.VALILQNVDLPN.- "sp|Q04446|GLGB_HUMAN,tr|E9PGM4|E9PGM4_HUMAN" 2 1307.7449 - 63105 21982 2 1307.745987 654.8797 "1,4-alpha-glucan-branching enzyme OS=Homo sapiens OX=9606 GN=GBE1 PE=1 SV=3" 3.8 3945.1 - 664024 - - - 0.8297 - 1.048 0.186 - 62.3 1 2 0 0.0011 12 0 0 0 - - - - - 0.5378 0.9987 230117_WJC_METTL3_WT_vs_EV_F07.21984.21984.2 3.53E-05 22-Aug R.TLITFAGMIPYR.T "sp|Q8N1F7|NUP93_HUMAN,tr|H3BV15|H3BV15_HUMAN" 2 1381.7428 -1 63107 21984 2 1381.746448 691.8787 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 8.41 3945.3 - 486630 - - - 2.6452 - 1.811 0.265 - 226.6 1 2 0 0.0037 12 0 0 0 0.00E+00 0.00E+00 - - - 2.5597 1 230117_WJC_METTL3_WT_vs_EV_F07.21988.21988.2 3.87E-07 26-Aug R.FGDPEC[160.03]QVILPLLK.S sp|P22102|PUR2_HUMAN 1 1627.8644 0.88 63111 21988 2 1627.868371 814.9395 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.37 3945.5 - 412483 - - - 2.4609 - 2.308 0.544 - 158.9 1 2 0 0.004 14 0 0 0 4.19E+06 4.74E+06 - - - 5.1566 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.21989.21989.2 0.000101 Aug-32 R.AIGLSPMSFPTADLTLK[136.11].M "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1768.9525 -1 63112 21989 2 1768.955132 885.4835 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.88 3945.6 - 290780 - - - 1.5116 - 2.018 0.491 - 178.5 1 2 0 0.0027 17 0 0 0 0.00E+00 0.00E+00 - - - 4.3928 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.21990.21990.2 0.018 18-Aug R.LLELQYFISR.D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1280.7129 -1 63113 21990 2 1280.712368 641.3637 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 6 3945.7 - 249731 - - - -0.3943 - 1.476 0.261 - 219.8 1 2 0 -0.0005 10 0 0 0 0.00E+00 0.00E+00 - - - 2.0553 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.21995.21995.3 5.20E-05 13/56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 4.06 63117 21995 3 1591.947614 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3946.3 - 5.54E+06 - - - 1.6426 - 2.375 0.448 - 176.4 1 2 0 0.0026 15 0 0 0 2.19E+07 5.39E+06 - - - 5.7911 1 230117_WJC_METTL3_WT_vs_EV_F07.21996.21996.2 4.05E-09 14/24 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 -1 63118 21996 2 1509.889728 755.9512 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3946.3 - 5.02E+06 - - - 1.2253 - 2.941 0.664 - 833.7 1 2 0 0.0019 13 0 0 0 0.00E+00 0.00E+00 - - - 6.7134 1 230117_WJC_METTL3_WT_vs_EV_F07.21997.21997.2 1.06E-07 13/28 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 4.43 63119 21997 2 1601.955502 801.9839 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3946.4 - 3.91E+06 - - - 1.3939 - 2.741 0.622 - 406.1 1 2 0 0.0022 15 0 0 0 1.03E+08 2.34E+07 - - - 6.1134 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.21998.21998.3 2.39E-07 Dec-48 K.LFYADHPFIFLVR.D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1636.8766 4.44 63120 21998 3 1636.877926 546.6328 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3946.4 - 2.55E+06 - - - 0.8192 - 2.497 0.453 - 155.8 1 2 0 0.0013 13 0 0 0 2.20E+07 4.95E+06 - - - 6.0712 1 230117_WJC_METTL3_WT_vs_EV_F07.22001.22001.3 7.53E-08 15/48 K.LFYADHPFIFLVR[166.11].D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1646.8849 4.15 63123 22001 3 1646.886786 549.9689 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3946.6 - 789794 - - - 1.1725 - 3.043 0.556 - 255.8 1 2 0 0.0019 13 0 0 0 1.97E+07 4.74E+06 - - - 7.7556 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22004.22004.2 7.48E-10 17/24 K.LFYADHPFIFLVR.D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1636.8766 2.83 63126 22004 2 1636.879781 819.4456 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3947 - 758130 - - - 1.9525 - 2.743 0.27 - 841.5 1 2 0 0.0032 13 0 0 0 5.65E+06 1.99E+06 - - - 3.624 1 230117_WJC_METTL3_WT_vs_EV_F07.22006.22006.2 4.23E-09 13/24 K.MFVLDEADEMLSR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 11 1564.7141 -1 63128 22006 2 1564.715035 783.3643 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 3.92 3947.2 - 679099 - - - 0.6065 - 2.733 0.609 - 525.1 1 2 0 0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 6.1192 0.9989 230117_WJC_METTL3_WT_vs_EV_F07.22008.22008.2 0.00865 28-Sep K.VVPTLPEGLPVLLEK[136.11].R "sp|Q6ZU65|UBN2_HUMAN,tr|H7C4P8|H7C4P8_HUMAN" 2 1610.9738 -1 63130 22008 2 1610.974292 806.4942 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 4.53 3947.4 - 618101 - - - 0.2769 - 1.807 0.281 - 117.7 1 2 0 0.0004 15 0 0 0 0.00E+00 0.00E+00 - - - 2.571 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.22009.22009.2 0.00843 18-Sep K.LLELQELVLR.L "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|A0A087WYC0|A0A087WYC0_HUMAN" 3 1224.7442 -1 63131 22009 2 1224.746906 613.3794 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 4.53 3947.5 - 570518 - - - 2.2307 - 2.038 0.296 - 202 1 2 0 0.0027 10 0 0 0 0.00E+00 0.00E+00 - - - 3.2137 1 230117_WJC_METTL3_WT_vs_EV_F07.22010.22010.2 0.00457 15/28 R.ALVEVLGPYEPLLSR[166.11].V "sp|Q86VR2|RETR3_HUMAN,tr|K7EMF4|K7EMF4_HUMAN,tr|K7ELM8|K7ELM8_HUMAN,tr|K7EJ34|K7EJ34_HUMAN,tr|K7ENF4|K7ENF4_HUMAN,tr|K7ENZ6|K7ENZ6_HUMAN" 6 1664.9377 -1 63132 22010 2 1664.938909 833.4761 Reticulophagy regulator 3 OS=Homo sapiens OX=9606 GN=RETREG3 PE=1 SV=1 4.53 3947.7 - 569844 - - - 0.7394 - 2.806 0.479 - 716 1 2 0 0.0012 15 0 0 0 0.00E+00 0.00E+00 - - - 5.1151 1 230117_WJC_METTL3_WT_vs_EV_F07.22011.22011.3 2.72E-06 16/48 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 -1 63133 22011 3 1509.890978 504.3032 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3947.8 - 512286 - - - 2.0531 - 2.955 0.531 - 446.1 1 2 0 0.0031 13 0 0 0 0.00E+00 0.00E+00 - - - 7.3969 1 230117_WJC_METTL3_WT_vs_EV_F07.22018.22018.2 5.26E-06 20-Sep K.SVFGGLVNYFK.S "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1229.6445 -1 63139 22018 2 1229.645661 615.8295 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 8.31 3948.3 - 3.13E+06 - - - 0.9775 - 1.882 0.56 - 202 1 2 0 0.0012 11 0 0 0 0.00E+00 0.00E+00 - - - 4.8874 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.22019.22019.2 0.291 16-Sep K.ILNIFGVIK.G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1015.643 1.76 63140 22019 2 1015.643372 508.8288 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3948.3 - 2.38E+06 - - - 0.3633 - 1.903 0.35 - 186.1 1 2 0 0.0004 9 0 0 0 4.02E+06 2.28E+06 - - - 3.4875 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.22021.22021.2 0.0197 16-Aug K.ILNIFGVIK[136.11].G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1023.6572 -1 63142 22021 2 1023.658101 512.8359 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3948.4 - 1.45E+06 - - - 0.8772 - 1.74 0.33 - 145.4 1 2 0 0.0009 9 0 0 0 0.00E+00 0.00E+00 - - - 3.0805 0.9927 230117_WJC_METTL3_WT_vs_EV_F07.22022.22022.3 0.0111 Aug-56 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 4.14 63143 22022 3 1601.95602 534.9917 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3948.5 - 1.24E+06 - - - 1.7173 - 1.405 0.206 - 71.9 1 2 0 0.0028 15 0 0 0 2.56E+07 6.19E+06 - - - 1.7232 0.9983 230117_WJC_METTL3_WT_vs_EV_F07.22025.22025.2 0.0439 18-Oct R.ALSPLEEWLR[166.11].L "sp|P26640|SYVC_HUMAN,tr|A0A0G2JJT9|A0A0G2JJT9_HUMAN,tr|A2ABF4|A2ABF4_HUMAN,tr|A0A140T936|A0A140T936_HUMAN,tr|A0A140T954|A0A140T954_HUMAN,tr|A0A140T904|A0A140T904_HUMAN" 6 1222.6585 -1 63146 22025 2 1222.659526 612.3365 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 4.53 3948.7 - 917577 - - - 0.804 - 1.57 0.223 - 328.5 1 2 0 0.001 10 0 0 0 0.00E+00 0.00E+00 - - - 1.9469 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.22026.22026.2 0.000215 18-Oct R.ALSPLEEWLR.L "sp|P26640|SYVC_HUMAN,tr|A0A0G2JJT9|A0A0G2JJT9_HUMAN,tr|A2ABF4|A2ABF4_HUMAN,tr|A0A140T936|A0A140T936_HUMAN,tr|A0A140T954|A0A140T954_HUMAN,tr|A0A140T904|A0A140T904_HUMAN" 6 1212.6503 3.58 63147 22026 2 1212.649663 607.3324 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 4.53 3948.7 - 805241 - - - -0.503 - 1.849 0.419 - 533.1 1 2 0 -0.0006 10 0 0 0 6.99E+06 1.95E+06 - - - 3.8512 1 230117_WJC_METTL3_WT_vs_EV_F07.22032.22032.2 1.31E-08 15/26 R.IVEPYVTWGFPNLK.S "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1661.8817 -1 63153 22032 2 1661.877799 831.9481 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6 3949.3 - 583067 - - - -2.3654 - 2.57 0.583 - 683 1 2 0 -0.0039 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7145 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.22033.22033.2 0.0591 20-Dec K.DTLTYFIYSVK.N sp|O75446|SAP30_HUMAN 1 1348.6915 -1 63154 22033 2 1348.691628 675.353 Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1 5.83 3949.4 - 549035 - - - 0.1179 - 1.209 0.286 - 298 1 2 0 0.0002 11 0 0 0 0.00E+00 0.00E+00 - - - 1.6668 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.22038.22038.2 0.434 13/22 K.IVILPDYLEIAR.D sp|P45974|UBP5_HUMAN 1 1413.8232 -1 63158 22038 2 1413.82825 707.9189 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 4.37 3950 - 1.68E+06 - - - 3.6058 - 2.362 0.437 - 524.8 1 2 0 0.0051 12 0 0 0 0.00E+00 0.00E+00 - - - 4.5286 1 230117_WJC_METTL3_WT_vs_EV_F07.22039.22039.2 0.000822 15/24 R.VNILEVASGAVLR.S sp|Q12788|TBL3_HUMAN 1 1339.7823 -1 63159 22039 2 1339.786329 670.8985 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3950.1 - 1.52E+06 - - - 2.9699 - 2.899 0.54 - 669.3 1 2 0 0.004 13 0 0 0 0.00E+00 0.00E+00 - - - 5.7599 1 230117_WJC_METTL3_WT_vs_EV_F07.22040.22040.2 0.0009 15/24 R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 63160 22040 2 1349.794523 675.9026 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3950.3 - 1.41E+06 - - - 2.8916 - 2.935 0.456 - 656.9 1 2 0 0.0039 13 0 0 0 0.00E+00 0.00E+00 - - - 5.1712 1 230117_WJC_METTL3_WT_vs_EV_F07.22041.22041.2 2.03E-07 16/26 R.IVEPYVTWGFPNLK[136.11].S "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1669.8959 -1 63161 22041 2 1669.900646 835.9552 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6 3950.4 - 1.13E+06 - - - 2.8241 - 2.644 0.571 - 858 1 2 0 0.0047 14 0 0 0 0.00E+00 0.00E+00 - - - 5.6968 0.9859 230117_WJC_METTL3_WT_vs_EV_F07.22042.22042.2 2.12E-07 24-Dec K.SIIGVIPYFPYSK.Q "sp|O60256|KPRB_HUMAN,tr|C9JJS3|C9JJS3_HUMAN,tr|C9JDU5|C9JDU5_HUMAN,tr|E7EPA1|E7EPA1_HUMAN,tr|E7EW35|E7EW35_HUMAN,tr|C9JDH0|C9JDH0_HUMAN,tr|C9K0K7|C9K0K7_HUMAN" 7 1482.8123 -1 63162 22042 2 1482.824023 742.4134 Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Homo sapiens OX=9606 GN=PRPSAP2 PE=1 SV=1 8.22 3950.5 - 768797 - - - 7.9376 - 2.135 0.386 - 530.3 1 2 0 0.0118 13 0 0 0 0.00E+00 0.00E+00 - - - 3.8349 1 230117_WJC_METTL3_WT_vs_EV_F07.22044.22044.2 1.80E-09 13/28 K.YFDTVPVAAAMC[160.03]VLK.T sp|Q15393|SF3B3_HUMAN 1 1683.8364 -1 63164 22044 2 1683.841663 842.9255 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.83 3950.8 - 677474 - - - 3.1042 - 2.651 0.631 - 411.9 1 2 0 0.0052 15 0 0 0 0.00E+00 0.00E+00 - - - 6.0969 1 230117_WJC_METTL3_WT_vs_EV_F07.22046.22046.2 7.95E-09 14/28 K.YFDTVPVAAAMC[160.03]VLK[136.11].T sp|Q15393|SF3B3_HUMAN 1 1691.8506 -1 63166 22046 2 1691.851033 846.9326 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.83 3951 - 638127 - - - 0.2347 - 2.695 0.584 - 444.3 1 2 0 0.0004 15 0 0 0 0.00E+00 0.00E+00 - - - 5.7917 1 230117_WJC_METTL3_WT_vs_EV_F07.22049.22049.4 1.20E-09 32/204 R.KIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 3974.1279 -1 63169 22049 4 3974.132831 994.5392 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.01 3951.4 - 457931 - - - 1.2435 - 4.501 0.679 - 411.6 1 2 0 0.0049 35 0 0 0 0.00E+00 0.00E+00 - - - 5.5806 1 230117_WJC_METTL3_WT_vs_EV_F07.22050.22050.2 1.13E-06 26-Oct R.LVLPPPDPLDLPLR.A "sp|Q15477|SKIV2_HUMAN,tr|B4E0B4|B4E0B4_HUMAN,tr|F8WDE8|F8WDE8_HUMAN" 3 1553.9181 2.03 63170 22050 2 1553.922459 777.9663 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 4.21 3951.6 - 406571 - - - 2.7955 - 2.171 0.501 - 288 1 2 0 0.0043 14 0 0 0 2.31E+06 1.14E+06 - - - 4.6853 0.9917 230117_WJC_METTL3_WT_vs_EV_F07.22053.22053.2 0.0227 20-Aug K.ATLWYVPLSLK[136.11].N "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1297.7526 -1 63173 22053 2 1297.758873 649.8836 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 8.63 3951.9 - 336842 - - - 4.8646 - 1.496 0.268 - 183.4 1 2 0 0.0063 11 0 0 0 0.00E+00 0.00E+00 - - - 2.1081 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22054.22054.3 0.000803 Sep-48 R.VNILEVASGAVLR.S sp|Q12788|TBL3_HUMAN 1 1339.7823 -1 63174 22054 3 1339.786099 447.6014 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3952.1 - 327687 - - - 2.7982 - 1.863 0.364 - 130.2 1 2 0 0.0037 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2841 0.9357 230117_WJC_METTL3_WT_vs_EV_F07.22056.22056.2 21.9 22-Jun K.LLDSSTVTHLFK.L "sp|P60900|PSA6_HUMAN,tr|G3V5Z7|G3V5Z7_HUMAN,tr|G3V295|G3V295_HUMAN,tr|G3V3I1|G3V3I1_HUMAN,tr|G3V3U4|G3V3U4_HUMAN" 5 1359.7398 1.66 63175 22056 2 1359.740764 680.8772 Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1 6.74 3952.4 - 414489 - - - 0.6965 - 1.016 0.029 - 80.7 1 2 0 0.0009 12 0 0 0 4.60E+06 2.77E+06 - - - -0.7033 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22058.22058.2 0.000712 20-Dec K.GFLSGLLDNVK.Q "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1161.6394 2.53 63177 22058 2 1161.640539 581.827 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.84 3952.5 - 5.25E+06 - - - 1.0029 - 2.255 0.406 - 412.2 1 2 0 0.0012 11 0 0 0 3.37E+07 1.33E+07 - - - 4.2391 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22059.22059.2 0.0018 20-Sep K.LILPELGPVFK[136.11].Q "sp|Q6P3W7|SCYL2_HUMAN,tr|H0YIK6|H0YIK6_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 1232.7624 0.69 63178 22059 2 1232.763694 617.3885 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6 3952.5 - 4.83E+06 - - - 1.0529 - 1.787 0.489 - 293.1 1 2 0 0.0013 11 0 0 0 3.20E+07 4.64E+07 - - - 4.2228 0.9831 230117_WJC_METTL3_WT_vs_EV_F07.22060.22060.2 1.22 20-May K.FVSISDLLVPK.D sp|P50395|GDIB_HUMAN 1 1216.7067 -1 63179 22060 2 1216.708778 609.3606 Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2 5.84 3952.6 - 3.29E+06 - - - 1.6873 - 0.896 0.188 - 65.8 1 2 0 0.0021 11 0 0 0 0.00E+00 0.00E+00 - - - 0.1318 1 230117_WJC_METTL3_WT_vs_EV_F07.22061.22061.2 2.66E-05 14/22 R.ANLGVFSVFAPR[166.11].G "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1286.7011 -1 63180 22061 2 1286.702039 644.3578 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 9.79 3952.6 - 2.33E+06 - - - 0.7476 - 2.886 0.512 - 864.1 1 2 0 0.001 12 0 0 0 0.00E+00 0.00E+00 - - - 5.611 0.9993 230117_WJC_METTL3_WT_vs_EV_F07.22062.22062.2 9.60E-06 24-Dec K.LAGFLDLTEQEFR[166.11].L "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 1547.7859 -1 63181 22062 2 1547.791488 774.9002 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.14 3952.6 - 2.08E+06 - - - 3.5916 - 2.487 0.404 - 666.8 1 2 0 0.0056 13 0 0 0 0.00E+00 0.00E+00 - - - 4.3615 0.9843 230117_WJC_METTL3_WT_vs_EV_F07.22065.22065.2 0.61 24-May K.AFTYSSTLISHK[136.11]R[166.11].L sp|A8MUV8|ZN727_HUMAN 1 1527.8164 0.02 63184 22065 2 1527.82012 764.9155 Putative zinc finger protein 727 OS=Homo sapiens OX=9606 GN=ZNF727 PE=5 SV=3 9.99 3952.8 - 1.70E+06 - - - 2.4041 - 1.035 0.165 - 54.2 1 2 0 0.0037 13 0 0 0 4.55E+05 2.60E+07 - - - 0.3468 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22067.22067.2 0.000119 26-Sep K.LDDIFEPVLIPEPK.L "sp|Q14008|CKAP5_HUMAN,tr|H0YEK7|H0YEK7_HUMAN,tr|H0YCF6|H0YCF6_HUMAN" 3 1623.876 -1 63186 22067 2 1623.876765 812.9453 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 3.92 3952.9 - 1.43E+06 - - - 0.4859 - 2.066 0.493 - 239.5 1 2 0 0.0008 14 0 0 0 0.00E+00 0.00E+00 - - - 4.5029 0.998 230117_WJC_METTL3_WT_vs_EV_F07.22068.22068.2 0.0364 16-May R.LFIFETFC[160.03]R[166.11].L "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 12 1241.6142 -1 63187 22068 2 1241.615702 621.8144 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 5.99 3953 - 1.35E+06 - - - 1.1807 - 1.186 0.297 - 80.1 1 2 0 0.0015 9 0 0 0 0.00E+00 0.00E+00 - - - 1.7277 1 230117_WJC_METTL3_WT_vs_EV_F07.22071.22071.3 2.10E-08 14/60 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 -1 63190 22071 3 1663.952278 555.6576 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3953.2 - 1.00E+06 - - - 0.845 - 2.575 0.587 - 192.2 1 2 0 0.0014 16 0 0 0 0.00E+00 0.00E+00 - - - 7.511 1 230117_WJC_METTL3_WT_vs_EV_F07.22074.22074.2 1.86E-06 22-Dec K.GVNSYPSLFIFR.S "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0TB22|A0A7P0TB22_HUMAN,tr|A0A7P0Z4F2|A0A7P0Z4F2_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN,tr|E7EP04|E7EP04_HUMAN,tr|A0A7P0T9B7|A0A7P0T9B7_HUMAN,tr|A0A494C1G5|A0A494C1G5_HUMAN,tr|A0A7P0TB83|A0A7P0TB83_HUMAN" 10 1398.7296 2.08 63193 22074 2 1398.732317 700.3721 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 8.75 3953.4 - 887877 - - - 1.9525 - 2.587 0.559 - 368.6 1 2 0 0.0027 12 0 0 0 9.34E+06 4.49E+06 - - - 5.6698 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22078.22078.3 5.24E-06 14/60 K.INEAIVAVQAIIADPK[136.11].T sp|Q9Y224|RTRAF_HUMAN 1 1671.9651 -1 63196 22078 3 1671.969205 558.329 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3953.8 - 1.55E+06 - - - 2.4719 - 2.542 0.494 - 211 1 2 0 0.0041 16 0 0 0 0.00E+00 0.00E+00 - - - 6.4403 1 230117_WJC_METTL3_WT_vs_EV_F07.22084.22084.2 2.40E-05 20-Nov K.EGLLGLQNLLK.S "sp|Q7Z460|CLAP1_HUMAN,sp|O75122|CLAP2_HUMAN,tr|E7ERI8|E7ERI8_HUMAN,tr|A0A804HJG7|A0A804HJG7_HUMAN,tr|J3KR49|J3KR49_HUMAN,tr|E7EW49|E7EW49_HUMAN,tr|E3W994|E3W994_HUMAN,tr|A0A0U1RQI6|A0A0U1RQI6_HUMAN,tr|F8WA11|F8WA11_HUMAN,tr|H0Y5T1|H0Y5T1_HUMAN" 10 1196.7129 -1 63202 22084 2 1196.716384 599.3637 CLIP-associating protein 1 OS=Homo sapiens OX=9606 GN=CLASP1 PE=1 SV=1 6.1 3954.2 - 3.25E+06 - - - 2.9339 - 2.353 0.485 - 326.8 1 2 0 0.0035 11 0 0 0 0.00E+00 0.00E+00 - - - 4.937 1 230117_WJC_METTL3_WT_vs_EV_F07.22086.22086.2 7.89E-06 13/30 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 -1 63204 22086 2 1663.953556 832.9827 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3954.4 - 2.16E+06 - - - 1.613 - 2.883 0.508 - 468.3 1 2 0 0.0027 16 0 0 0 0.00E+00 0.00E+00 - - - 5.3954 0.9982 230117_WJC_METTL3_WT_vs_EV_F07.22087.22087.3 0.0734 Sep-48 R.IESILMSLPLTAR.W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1442.8167 1.18 63205 22087 3 1442.820565 481.9462 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3954.5 - 2.01E+06 - - - 2.6878 - 1.743 0.264 - 106 1 2 0 0.0039 13 0 0 0 3.78E+06 3.21E+06 - - - 2.9887 1 230117_WJC_METTL3_WT_vs_EV_F07.22089.22089.2 7.69E-05 13/22 R.ANLGVFSVFAPR.G "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1276.6928 0.85 63207 22089 2 1276.696676 639.3537 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 9.79 3954.6 - 1.87E+06 - - - 3.0305 - 2.673 0.484 - 733.5 1 2 0 0.0039 12 0 0 0 5.87E+06 6.88E+06 - - - 5.2016 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.22090.22090.3 0.0461 Sep-48 R.IESILMSLPLTAR[166.11].W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1452.825 1.64 63208 22090 3 1452.82858 485.2823 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3954.7 - 1.67E+06 - - - 2.4938 - 2.067 0.294 - 112.9 1 2 0 0.0036 13 0 0 0 5.37E+06 3.28E+06 - - - 3.7855 1 230117_WJC_METTL3_WT_vs_EV_F07.22091.22091.2 0.0045 20-Nov K.DVLLPWYNAYR[166.11].F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1418.7222 -1 63209 22091 2 1418.727858 710.3684 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3954.8 - 1.48E+06 - - - 3.9839 - 2.234 0.481 - 420.9 1 2 0 0.0057 11 0 0 0 0.00E+00 0.00E+00 - - - 4.7663 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22094.22094.2 7.01E-06 13/30 K.INEAIVAVQAIIADPK[136.11].T sp|Q9Y224|RTRAF_HUMAN 1 1671.9651 -1 63212 22094 2 1671.965352 836.9898 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3955.2 - 1.36E+06 - - - 0.1675 - 2.456 0.426 - 296.2 1 2 0 0.0003 16 0 0 0 0.00E+00 0.00E+00 - - - 4.3964 1 230117_WJC_METTL3_WT_vs_EV_F07.22095.22095.2 6.31E-11 23/34 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 8.25 63213 22095 2 1911.951454 956.9806 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3955.3 - 1.28E+06 - - - 2.5518 - 4.5 0.648 - 2216.2 1 2 0 0.0049 18 0 0 0 2.92E+07 3.54E+06 - - - 7.5234 0.992 230117_WJC_METTL3_WT_vs_EV_F07.22096.22096.2 4.5 12-Aug K.EVLLEVK.Y "sp|Q13884|SNTB1_HUMAN,sp|Q13425|SNTB2_HUMAN,tr|A0A3B3ITC2|A0A3B3ITC2_HUMAN,tr|H0YCS0|H0YCS0_HUMAN" 4 828.4957 -1 63214 22096 2 828.496909 415.2551 Beta-1-syntrophin OS=Homo sapiens OX=9606 GN=SNTB1 PE=1 SV=3 4.53 3955.5 - 1.26E+06 - - - 1.4955 - 1.303 0.102 - 153.3 1 2 0 0.0012 7 0 0 0 0.00E+00 0.00E+00 - - - 0.6326 1 230117_WJC_METTL3_WT_vs_EV_F07.22103.22103.2 8.07E-06 13/18 K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 999 63220 22103 2 1146.628487 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3956 - 7.29E+06 - - - 0.0105 - 2.353 0.533 - 473.1 1 2 0 0 10 0 0 0 2.66E+07 0.00E+00 - - - 5.3662 0.9986 230117_WJC_METTL3_WT_vs_EV_F07.22106.22106.2 0.00179 20-Sep K.DVLLPWYNAYR.F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1408.7139 -1 63223 22106 2 1408.712506 705.3642 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3956.1 - 2.55E+06 - - - -1.0151 - 1.651 0.384 - 276.3 1 2 0 -0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 3.2331 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.22107.22107.2 0.045 20-Aug K.DLLEVADVLEK[136.11].A sp|Q9HAV7|GRPE1_HUMAN 1 1250.6849 1.7 63224 22107 2 1250.686306 626.3497 "GrpE protein homolog 1, mitochondrial OS=Homo sapiens OX=9606 GN=GRPEL1 PE=1 SV=2" 3.92 3956.2 - 2.38E+06 - - - 1.097 - 1.945 0.25 - 180.1 1 2 0 0.0014 11 0 0 0 1.04E+07 6.11E+06 - - - 2.6868 0.8708 230117_WJC_METTL3_WT_vs_EV_F07.22116.22116.2 8.95E-06 16-Oct F.AAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 999.5601 5.15 63233 22116 2 999.558395 500.7873 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3957 - 624716 - - - -1.6667 - 2.017 0.313 - 434.2 1 1 0 -0.0017 9 0 0 0 3.13E+06 6.07E+05 - - - 3.3821 1 230117_WJC_METTL3_WT_vs_EV_F07.22127.22127.2 1.72E-12 19/34 K.LGGSLADSYLDEGFLLDK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1919.9608 8.25 63243 22127 2 1919.960734 960.9877 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3958.1 - 1.35E+06 - - - -0.0214 - 4.069 0.651 - 1503 1 2 0 0 18 0 0 0 2.92E+07 3.54E+06 - - - 7.2996 1 230117_WJC_METTL3_WT_vs_EV_F07.22129.22129.2 5.36E-05 22-Dec R.LTLAELNQILYR.C sp|P35573|GDE_HUMAN 1 1445.8242 1.41 63245 22129 2 1445.829009 723.9194 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 6 3958.4 - 898604 - - - 3.3158 - 2.655 0.41 - 627.3 1 2 0 0.0048 12 0 0 0 5.72E+06 4.04E+06 - - - 4.6369 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.22130.22130.2 0.000397 18-Oct K.DWVFLNYTYK[136.11].R "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN" 2 1355.6641 0.26 63246 22130 2 1355.663869 678.8393 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.83 3958.5 - 810893 - - - -0.1992 - 1.91 0.46 - 344.6 1 2 0 -0.0003 10 0 0 0 7.26E+05 2.83E+06 - - - 4.2447 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22141.22141.2 1.33E-06 20-Dec K.VMVQPINLIFR.Y sp|P62304|RUXE_HUMAN 1 1328.7639 1.35 63255 22141 2 1328.764795 665.3892 Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1 9.72 3959.9 - 1.88E+07 - - - 0.7014 - 1.9 0.511 - 479.9 1 2 0 0.0009 11 0 0 0 5.62E+07 4.16E+07 - - - 4.5513 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22147.22147.2 0.141 16-Nov R.C[160.03]LLAYFLDK.S "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1141.5842 3.22 63260 22147 2 1141.585983 571.7994 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 5.83 3960.3 - 1.66E+06 - - - 1.5899 - 2.192 0.401 - 436.3 1 2 0 0.0018 9 0 0 0 1.27E+07 3.94E+06 - - - 4.2727 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22148.22148.3 5.15E-07 13/44 R.FFALPYVDHFLR[166.11].L sp|Q9HD33|RM47_HUMAN 1 1533.8008 0.91 63261 22148 3 1533.80089 512.2742 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 6.74 3960.3 - 1.32E+06 - - - 0.0645 - 2.299 0.403 - 158.6 1 2 0 0.0001 12 0 0 0 5.47E+06 6.01E+06 - - - 5.3405 0.9998 230117_WJC_METTL3_WT_vs_EV_F07.22149.22149.3 2.10E-06 16/44 R.FFALPYVDHFLR.L sp|Q9HD33|RM47_HUMAN 1 1523.7925 0.92 63262 22149 3 1523.793537 508.9381 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 6.74 3960.4 - 1.31E+06 - - - 0.6668 - 2.683 0.31 - 272.1 1 2 0 0.001 12 0 0 0 5.47E+06 5.91E+06 - - - 4.7316 1 230117_WJC_METTL3_WT_vs_EV_F07.22151.22151.2 5.29E-05 20-Nov R.IAFWDDVYGFK.M sp|O60678|ANM3_HUMAN 1 1359.6499 -1 63264 22151 2 1359.650537 680.8322 Protein arginine N-methyltransferase 3 OS=Homo sapiens OX=9606 GN=PRMT3 PE=1 SV=4 4.21 3960.6 - 969410 - - - 0.4398 - 2.378 0.523 - 399 1 2 0 0.0006 11 0 0 0 0.00E+00 0.00E+00 - - - 5.2471 1 230117_WJC_METTL3_WT_vs_EV_F07.22152.22152.2 0.000136 14/28 K.AVLDSYEYFAVLAAK[136.11].E sp|P82664|RT10_HUMAN 1 1666.8698 -1 63265 22152 2 1666.872421 834.4422 "28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2" 4.37 3960.8 - 922830 - - - 1.5874 - 2.683 0.537 - 451.9 1 2 0 0.0026 15 0 0 0 0.00E+00 0.00E+00 - - - 5.4329 1 230117_WJC_METTL3_WT_vs_EV_F07.22156.22156.2 4.74E-06 20-Dec R.IAFWDDVYGFK[136.11].M sp|O60678|ANM3_HUMAN 1 1367.6641 -1 63269 22156 2 1367.664283 684.8393 Protein arginine N-methyltransferase 3 OS=Homo sapiens OX=9606 GN=PRMT3 PE=1 SV=4 4.21 3961.3 - 792408 - - - 0.1053 - 2.398 0.529 - 472.5 1 2 0 0.0001 11 0 0 0 0.00E+00 0.00E+00 - - - 5.3142 0.9974 230117_WJC_METTL3_WT_vs_EV_F07.22169.22169.2 0.0364 16-Sep K.DLIQMLVQR.G "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1114.6169 -1 63281 22169 2 1114.615349 558.3157 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 5.84 3962.6 - 1.06E+06 - - - -1.3601 - 1.709 0.282 - 245 1 2 0 -0.0015 9 0 0 0 0.00E+00 0.00E+00 - - - 2.6738 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22171.22171.2 0.00281 16-Nov K.AGLVELLLR.E "sp|Q13425|SNTB2_HUMAN,tr|A0A140TA73|A0A140TA73_HUMAN" 2 982.6175 -1 63283 22171 2 982.618463 492.316 Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1 6.05 3962.8 - 810769 - - - 0.9638 - 2.48 0.378 - 380 1 2 0 0.0009 9 0 0 0 0.00E+00 0.00E+00 - - - 4.4603 1 230117_WJC_METTL3_WT_vs_EV_F07.22185.22185.2 2.87E-08 22-Dec K.LIC[160.03]C[160.03]DILDVLDK.H "sp|P62258|1433E_HUMAN,tr|K7EIT4|K7EIT4_HUMAN" 2 1475.7364 1.48 63295 22185 2 1475.736755 738.8755 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 3.93 3964.4 - 4.34E+06 - - - 0.2487 - 2.553 0.657 - 401.9 1 2 0 0.0004 12 0 0 0 1.60E+07 1.08E+07 - - - 6.3596 1 230117_WJC_METTL3_WT_vs_EV_F07.22187.22187.2 7.56E-09 16/28 R.LGLEFFDQPAVPLAR[166.11].A "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1681.9067 1.19 63297 22187 2 1681.907512 841.9606 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 4.37 3964.5 - 3.60E+06 - - - 0.4757 - 2.955 0.591 - 651.3 1 2 0 0.0008 15 0 0 0 1.71E+07 1.44E+07 - - - 6.0697 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22188.22188.2 0.000521 14/24 R.ALTLGALTLPLAR.L sp|Q9BSJ8|ESYT1_HUMAN 1 1308.8129 -1 63298 22188 2 1308.81424 655.4137 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 9.79 3964.6 - 3.24E+06 - - - 1.007 - 2.774 0.388 - 772.3 1 2 0 0.0013 13 0 0 0 0.00E+00 0.00E+00 - - - 4.525 1 230117_WJC_METTL3_WT_vs_EV_F07.22190.22190.2 0.00145 14/24 R.ALTLGALTLPLAR[166.11].L sp|Q9BSJ8|ESYT1_HUMAN 1 1318.8212 1.33 63300 22190 2 1318.821843 660.4179 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 9.79 3964.7 - 2.48E+06 - - - 0.4936 - 2.31 0.507 - 673.9 1 2 0 0.0007 13 0 0 0 1.07E+07 8.06E+06 - - - 4.9343 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22191.22191.2 0.000331 13/26 K.VPGLPTPIENMILR.Y "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1548.8698 1.6 63301 22191 2 1548.871378 775.4422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3964.8 - 1.67E+06 - - - 1.0285 - 2.235 0.432 - 360.6 1 2 0 0.0016 14 0 0 0 8.23E+06 5.15E+06 - - - 4.2495 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22192.22192.3 0.00672 14/56 R.LGLEFFDQPAVPLAR[166.11].A "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1681.9067 -1 63302 22192 3 1681.907204 561.6428 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 4.37 3964.8 - 1.42E+06 - - - 0.2925 - 2.741 0.409 - 229.3 1 2 0 0.0005 15 0 0 0 0.00E+00 0.00E+00 - - - 5.7309 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22194.22194.2 0.00878 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 31.57 63304 22194 2 1006.570199 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3965 - 1.18E+06 - - - 0.299 - 1.747 0.454 - 257.9 1 2 0 0.0003 9 0 0 0 8.01E+06 2.54E+05 - - - 4.0082 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22195.22195.2 9.34E-05 14/26 K.VPGLPTPIENMILR[166.11].Y "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1558.8781 1.6 63305 22195 2 1558.877905 780.4463 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 3965.1 - 1.09E+06 - - - -0.0962 - 2.163 0.463 - 388.3 1 2 0 -0.0001 14 0 0 0 8.23E+06 5.15E+06 - - - 4.3967 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22196.22196.2 0.000253 20-Oct K.EVLDSFLDLAR.N sp|Q15758|AAAT_HUMAN 1 1276.6663 1.14 63306 22196 2 1276.668256 639.3404 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 4.03 3965.3 - 993022 - - - 1.5188 - 2.163 0.433 - 322.1 1 2 0 0.0019 11 0 0 0 6.80E+06 5.99E+06 - - - 4.3256 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22198.22198.2 0.000224 13/26 R.VGVDPLIIPTDYWK.K "sp|Q9NQW7|XPP1_HUMAN,tr|Q5T6H2|Q5T6H2_HUMAN,tr|Q5T6H3|Q5T6H3_HUMAN,tr|Q5T6H7|Q5T6H7_HUMAN" 4 1614.8657 -1 63308 22198 2 1614.866483 808.4401 Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3 4.21 3965.5 - 913112 - - - 0.457 - 2.081 0.417 - 212.6 1 2 0 0.0007 14 0 0 0 0.00E+00 0.00E+00 - - - 3.9598 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22206.22206.2 0.0128 16-Sep R.FLILPDMLK.N sp|P62318|SMD3_HUMAN 1 1088.6304 1.51 63315 22206 2 1088.630962 545.3225 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.84 3966.5 - 1.22E+07 - - - 0.5263 - 1.717 0.418 - 252.8 1 2 0 0.0006 9 0 0 0 4.62E+07 3.05E+07 - - - 3.6921 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.22207.22207.2 0.0034 16-Aug R.FLILPDMLK[136.11].N sp|P62318|SMD3_HUMAN 1 1096.6446 1.51 63316 22207 2 1096.645358 549.3296 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.84 3966.5 - 1.01E+07 - - - 0.7012 - 1.622 0.387 - 171.5 1 2 0 0.0008 9 0 0 0 4.62E+07 3.05E+07 - - - 3.2984 1 230117_WJC_METTL3_WT_vs_EV_F07.22208.22208.2 1.27E-05 17/26 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.3 63317 22208 2 1676.899116 839.4565 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3966.5 - 8.36E+06 - - - 0.3662 - 3.175 0.541 - 1091.9 1 2 0 0.0006 14 0 0 0 3.54E+07 2.72E+07 - - - 5.9358 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22209.22209.2 2.25E-05 20-Oct K.TFSFAIPLIEK[136.11].L sp|Q9NR30|DDX21_HUMAN 1 1272.7209 1.03 63318 22209 2 1272.721939 637.3677 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.66 3966.6 - 7.23E+06 - - - 0.7967 - 1.882 0.515 - 221.4 1 2 0 0.001 11 0 0 0 6.39E+07 6.23E+07 - - - 4.5551 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22210.22210.2 0.000315 20-Nov K.TFSFAIPLIEK.L sp|Q9NR30|DDX21_HUMAN 1 1264.7067 1.03 63319 22210 2 1264.70724 633.3606 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.66 3966.6 - 6.61E+06 - - - 0.4072 - 1.766 0.468 - 279 1 2 0 0.0005 11 0 0 0 6.39E+07 6.23E+07 - - - 4.036 1 230117_WJC_METTL3_WT_vs_EV_F07.22212.22212.3 6.53E-08 15/52 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.46 63321 22212 3 1676.900319 559.9734 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3966.7 - 3.30E+06 - - - 1.0835 - 2.859 0.569 - 309.9 1 2 0 0.0018 14 0 0 0 1.09E+07 7.46E+06 - - - 7.6749 1 230117_WJC_METTL3_WT_vs_EV_F07.22216.22216.2 0.000862 13/22 R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 -1 63325 22216 2 1328.717068 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3967 - 2.27E+06 - - - -1.2636 - 2.408 0.506 - 438.3 1 2 0 -0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 5.0901 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22217.22217.3 0.000169 17/44 K.C[160.03]LVFSLIGLHFK[136.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1440.8043 0.69 63326 22217 3 1440.805149 481.2754 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3967.1 - 1.98E+06 - - - 0.6045 - 2.824 0.44 - 394.1 1 2 0 0.0009 12 0 0 0 4.31E+06 6.25E+06 - - - 6.3229 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22219.22219.3 8.90E-06 16/44 K.C[160.03]LVFSLIGLHFK.L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1432.7901 0.68 63328 22219 3 1432.790219 478.604 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.23 3967.2 - 1.48E+06 - - - 0.0984 - 2.592 0.46 - 457.6 1 2 0 0.0001 12 0 0 0 4.16E+06 6.14E+06 - - - 6.3085 0.9856 230117_WJC_METTL3_WT_vs_EV_F07.22220.22220.2 0.207 12-Jul K.DVLDSVL.- sp|P81605|DCD_HUMAN 1 759.4014 - 63329 22220 2 759.401188 380.708 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.56 3967.3 - 1.43E+06 - - - -0.3253 - 1.12 0.165 - 169 1 2 0 -0.0002 7 0 0 0 - - - - - 0.6187 0.997 230117_WJC_METTL3_WT_vs_EV_F07.22221.22221.2 0.00497 24-Dec R.DPQLVPILIEAAR.N "sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 2 1433.8242 -1 63330 22221 2 1433.819699 717.9194 "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=NSDHL PE=1 SV=2" 4.37 3967.4 - 991044 - - - -3.1496 - 2.274 0.421 - 346.8 1 2 0 -0.0045 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2576 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22225.22225.2 0.000154 14-Oct R.C[160.03]FLSWLVK.L sp|Q92900|RENT1_HUMAN 1 1051.5525 -1 63333 22225 2 1051.553504 526.7835 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.22 3967.8 - 1.70E+06 - - - 0.9795 - 1.925 0.47 - 430.6 1 2 0 0.001 8 0 0 0 0.00E+00 0.00E+00 - - - 4.4873 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22228.22228.3 1.57E-05 15/68 K.LLGTIYTAAEEIEAVGGK.A sp|Q6YN16|HSDL2_HUMAN 1 1833.9724 -1 63336 22228 3 1833.973157 612.3314 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3968 - 2.31E+06 - - - 0.4155 - 2.757 0.449 - 335.9 1 2 0 0.0008 18 0 0 0 0.00E+00 0.00E+00 - - - 6.071 1 230117_WJC_METTL3_WT_vs_EV_F07.22229.22229.2 1.22E-10 19/34 K.LLGTIYTAAEEIEAVGGK.A sp|Q6YN16|HSDL2_HUMAN 1 1833.9724 -1 63337 22229 2 1833.974391 917.9935 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3968 - 1.82E+06 - - - 1.0883 - 3.866 0.646 - 1290 1 2 0 0.002 18 0 0 0 0.00E+00 0.00E+00 - - - 7.1362 1 230117_WJC_METTL3_WT_vs_EV_F07.22234.22234.2 0.0632 20-Dec K.LVLADLLEPVK.T sp|Q9BVJ6|UT14A_HUMAN 1 1208.738 1.55 63342 22234 2 1208.743962 605.3763 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3968.4 - 1.51E+06 - - - 4.9109 - 2.248 0.477 - 408.7 1 2 0 0.0059 11 0 0 0 2.83E+07 1.83E+07 - - - 4.7536 0.997 230117_WJC_METTL3_WT_vs_EV_F07.22237.22237.2 0.00986 20-Sep K.VNLLSVLEAAK[136.11].M sp|Q9BRX8|PXL2A_HUMAN 1 1163.7005 -1 63345 22237 2 1163.698847 582.8575 Peroxiredoxin-like 2A OS=Homo sapiens OX=9606 GN=PRXL2A PE=1 SV=3 5.97 3968.6 - 881388 - - - -1.4411 - 1.49 0.331 - 166.2 1 2 0 -0.0017 11 0 0 0 0.00E+00 0.00E+00 - - - 2.564 1 230117_WJC_METTL3_WT_vs_EV_F07.22240.22240.2 4.76E-09 15/34 K.LLGTIYTAAEEIEAVGGK[136.11].A sp|Q6YN16|HSDL2_HUMAN 1 1841.9866 -1 63348 22240 2 1841.986854 922.0006 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3969 - 771170 - - - 0.1406 - 2.947 0.611 - 718.3 1 2 0 0.0003 18 0 0 0 0.00E+00 0.00E+00 - - - 6.2109 1 230117_WJC_METTL3_WT_vs_EV_F07.22241.22241.2 9.41E-08 26-Dec K.VVQSYVEGLC[160.03]WVLR.Y sp|Q9H0D6|XRN2_HUMAN 1 1706.8814 -1 63349 22241 2 1706.87647 854.448 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.97 3969.1 - 551950 - - - -2.8953 - 2.665 0.6 - 511.9 1 2 0 -0.0049 14 0 0 0 0.00E+00 0.00E+00 - - - 5.9308 1 230117_WJC_METTL3_WT_vs_EV_F07.22249.22249.2 8.45E-06 18-Nov K.GGFDWNLVFK.W sp|Q10471|GALT2_HUMAN 1 1181.5869 -1 63356 22249 2 1181.587053 591.8007 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.84 3969.9 - 4.48E+06 - - - 0.0914 - 1.978 0.585 - 282.6 1 2 0 0.0001 10 0 0 0 0.00E+00 0.00E+00 - - - 5.2657 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22250.22250.2 9.06E-05 20-Dec K.LVLADLLEPVK[136.11].T sp|Q9BVJ6|UT14A_HUMAN 1 1216.7522 -1 63357 22250 2 1216.752522 609.3834 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3969.9 - 4.13E+06 - - - 0.2433 - 2.097 0.419 - 405.8 1 2 0 0.0003 11 0 0 0 0.00E+00 0.00E+00 - - - 4.1389 1 230117_WJC_METTL3_WT_vs_EV_F07.22251.22251.2 1.10E-05 18-Oct K.GGFDWNLVFK[136.11].W sp|Q10471|GALT2_HUMAN 1 1189.6011 -1 63358 22251 2 1189.59619 595.8078 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.84 3970 - 3.79E+06 - - - -4.1653 - 1.873 0.561 - 220.7 1 2 0 -0.005 10 0 0 0 0.00E+00 0.00E+00 - - - 4.9346 1 230117_WJC_METTL3_WT_vs_EV_F07.22253.22253.2 0.000254 14/24 K.IPLKPPPLELLNV.- sp|O15504|NUP42_HUMAN 1 1441.8908 1.78 63360 22253 2 1441.891938 721.9527 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 3970.1 - 2.88E+06 - - - 0.7629 - 2.332 0.517 - 630 1 2 0 0.0011 13 0 0 0 9.14E+06 5.15E+06 - - - 5.0324 1 230117_WJC_METTL3_WT_vs_EV_F07.22254.22254.2 6.09E-06 13/22 K.QFEELTLGEFLK.L "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1452.75 2.97 63361 22254 2 1452.750684 727.3823 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.25 3970.2 - 2.81E+06 - - - 0.4385 - 2.393 0.468 - 750.5 1 2 0 0.0006 12 0 0 0 5.60E+06 1.88E+06 - - - 4.7933 0.9643 230117_WJC_METTL3_WT_vs_EV_F07.22258.22258.2 0.579 12-Jun K.NIFLLFK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 893.5375 -1 63365 22258 2 893.537427 447.776 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.75 3970.5 - 1.45E+06 - - - -0.0537 - 1.303 0.001 - 112.6 1 2 0 0 7 0 0 0 0.00E+00 0.00E+00 - - - -0.113 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.22259.22259.2 0.000261 22-Oct K.QFEELTLGEFLK[136.11].L "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1460.7642 -1 63366 22259 2 1460.768571 731.3894 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.25 3970.6 - 1.29E+06 - - - 2.9601 - 2.078 0.377 - 369.9 1 2 0 0.0043 12 0 0 0 0.00E+00 0.00E+00 - - - 3.7486 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.22267.22267.2 0.000115 28-Oct K.VNALLPTETFIPVIR.G "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1681.9767 -1 63373 22267 2 1681.980712 841.9956 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.97 3971.6 - 534746 - - - 2.3895 - 1.985 0.196 - 224.1 1 2 0 0.004 15 0 0 0 0.00E+00 0.00E+00 - - - 2.173 1 230117_WJC_METTL3_WT_vs_EV_F07.22269.22269.2 2.43E-05 18-Dec K.STLLLLLTGK[136.11].L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1065.6889 -1 63375 22269 2 1065.689029 533.8517 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3971.7 - 6.93E+06 - - - 0.1239 - 2.309 0.452 - 558.8 1 2 0 0.0001 10 0 0 0 0.00E+00 0.00E+00 - - - 4.7152 1 230117_WJC_METTL3_WT_vs_EV_F07.22270.22270.2 1.02E-06 18-Oct K.STLLLLLTGK.L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1057.6747 -1 63376 22270 2 1057.6753 529.8446 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3971.7 - 6.76E+06 - - - 0.5701 - 2.056 0.56 - 353.4 1 2 0 0.0006 10 0 0 0 0.00E+00 0.00E+00 - - - 5.1888 0.9842 230117_WJC_METTL3_WT_vs_EV_F07.22271.22271.2 0.0158 14-Jul R.GFGFILFK[136.11].D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 935.536 0.83 63377 22271 2 935.534168 468.7753 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3971.8 - 6.64E+06 - - - -1.985 - 1.375 0.181 - 141.9 1 2 0 -0.0019 8 0 0 0 3.89E+07 4.67E+07 - - - 1.3377 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22274.22274.2 0.000927 16-Oct R.VNILFDFVK.K sp|P55010|IF5_HUMAN 1 1093.6172 -1 63380 22274 2 1093.619669 547.8159 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.81 3972 - 3.27E+06 - - - 2.2741 - 2.074 0.453 - 449.6 1 2 0 0.0025 9 0 0 0 0.00E+00 0.00E+00 - - - 4.4965 0.9946 230117_WJC_METTL3_WT_vs_EV_F07.22276.22276.2 0.0258 14-Aug R.GFGFILFK.D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 927.5218 0.83 63382 22276 2 927.521318 464.7682 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3972.1 - 2.39E+06 - - - -0.5466 - 1.465 0.173 - 181.4 1 2 0 -0.0005 8 0 0 0 3.89E+07 4.67E+07 - - - 1.4703 0.9867 230117_WJC_METTL3_WT_vs_EV_F07.22277.22277.2 0.38 14-Aug K.GSLLDFLK.E "sp|P07947|YES_HUMAN,sp|P09769|FGR_HUMAN,sp|P07948|LYN_HUMAN,sp|P08631|HCK_HUMAN,sp|P06241|FYN_HUMAN,sp|P12931|SRC_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|J3QRU1|J3QRU1_HUMAN" 9 891.5066 -1 63383 22277 2 891.506313 446.7606 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 3972.2 - 1.97E+06 - - - -0.2872 - 1.433 0.09 - 205.1 2 2 0 -0.0003 8 0 0 0 0.00E+00 0.00E+00 - - - 0.6562 0.9942 230117_WJC_METTL3_WT_vs_EV_F07.22279.22279.2 2.73 16-Aug K.EVIASIISR[166.11].Y "sp|Q99551|MTEF1_HUMAN,tr|C9JNM8|C9JNM8_HUMAN,tr|B4DPR9|B4DPR9_HUMAN,tr|C9JE25|C9JE25_HUMAN" 4 996.5843 0.001 63385 22279 2 996.585496 499.2994 "Transcription termination factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=MTERF1 PE=1 SV=1" 6.1 3972.4 - 1.52E+06 - - - 1.184 - 1.576 0.087 - 139.9 2 2 0 0.0012 9 0 0 0 0.00E+00 4.53E+06 - - - 0.8648 1 230117_WJC_METTL3_WT_vs_EV_F07.22280.22280.2 3.07E-05 20-Sep R.LWGLTEMFPER.V sp|Q9NS69|TOM22_HUMAN 1 1377.6751 -1 63386 22280 2 1377.674431 689.8448 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 4.53 3972.4 - 1.31E+06 - - - -0.4914 - 2.103 0.489 - 273 1 2 0 -0.0007 11 0 0 0 0.00E+00 0.00E+00 - - - 4.6635 1 230117_WJC_METTL3_WT_vs_EV_F07.22281.22281.2 0.000474 18-Nov K.ILYDILAFAK.E "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1165.6747 -1 63387 22281 2 1165.675973 583.8446 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.83 3972.6 - 1.28E+06 - - - 1.0946 - 2.294 0.443 - 274.1 1 2 0 0.0013 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6302 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.22282.22282.2 0.441 24-Sep K.IPLK[136.11]PPPLELLNV.- sp|O15504|NUP42_HUMAN 1 1449.905 1.78 63388 22282 2 1449.906381 725.9598 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 3972.7 - 1.22E+06 - - - 0.9263 - 1.492 0.252 - 123.5 1 2 0 0.0013 13 0 0 0 9.14E+06 5.15E+06 - - - 1.9288 0.9904 230117_WJC_METTL3_WT_vs_EV_F07.22283.22283.2 0.0927 18-Sep R.TLWSLVAFPK.L sp|Q93034|CUL5_HUMAN 1 1160.6594 -1 63389 22283 2 1160.658712 581.337 Cullin-5 OS=Homo sapiens OX=9606 GN=CUL5 PE=1 SV=4 8.41 3972.8 - 1.20E+06 - - - -0.5764 - 1.262 0.181 - 205 1 2 0 -0.0007 10 0 0 0 0.00E+00 0.00E+00 - - - 1.0272 1 230117_WJC_METTL3_WT_vs_EV_F07.22284.22284.2 7.12E-06 18-Dec K.ILYDILAFAK[136.11].E "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1173.6889 -1 63390 22284 2 1173.691386 587.8517 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.83 3972.8 - 1.15E+06 - - - 2.1207 - 2.487 0.48 - 338.5 1 2 0 0.0025 10 0 0 0 0.00E+00 0.00E+00 - - - 5.1286 1 230117_WJC_METTL3_WT_vs_EV_F07.22287.22287.2 0.000304 20-Nov R.YFGELLADLSR.K sp|Q8WVV4|POF1B_HUMAN 1 1282.6558 -1 63392 22287 2 1282.651079 642.3352 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 4.37 3973.2 - 1.43E+06 - - - -3.6432 - 2.147 0.599 - 384.5 1 2 0 -0.0047 11 0 0 0 0.00E+00 0.00E+00 - - - 5.5307 1 230117_WJC_METTL3_WT_vs_EV_F07.22292.22292.3 1.11E-10 21/80 N.WITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 2344.2539 4.69 63397 22292 3 2344.257795 782.4253 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3973.6 - 2.13E+06 - - - 1.6487 - 3.941 0.624 - 315.4 1 1 0 0.0039 21 0 0 0 7.72E+06 1.65E+06 - - - 8.7839 1 230117_WJC_METTL3_WT_vs_EV_F07.22293.22293.2 7.06E-05 14/24 R.LLSLISIALPENK.V "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1409.8494 -1 63398 22293 2 1409.851242 705.932 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 6 3973.7 - 1.80E+06 - - - 1.3299 - 2.831 0.533 - 646.7 1 2 0 0.0019 13 0 0 0 0.00E+00 0.00E+00 - - - 5.648 1 230117_WJC_METTL3_WT_vs_EV_F07.22294.22294.2 3.40E-07 15/22 R.LGDPLEAFPVFK[136.11].K "sp|Q86UY6|NAA40_HUMAN,tr|F5H2C9|F5H2C9_HUMAN" 2 1339.7267 1.46 63399 22294 2 1339.723498 670.8706 N-alpha-acetyltransferase 40 OS=Homo sapiens OX=9606 GN=NAA40 PE=1 SV=1 4.37 3973.7 - 1.73E+06 - - - -2.4192 - 3.06 0.621 - 959.2 1 2 0 -0.0032 12 0 0 0 9.64E+06 6.58E+06 - - - 6.5694 0.9733 230117_WJC_METTL3_WT_vs_EV_F07.22296.22296.2 0.000109 26-Nov K.IFFIDPNERPVTLY.H "sp|O95619|YETS4_HUMAN,tr|F8W1B9|F8W1B9_HUMAN,tr|F8VTR4|F8VTR4_HUMAN" 3 1722.8981 -1 63401 22296 2 1722.898616 862.4563 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 4.37 3973.9 - 1.33E+06 - - - 0.2949 - 2.196 0.454 - 213.7 1 1 0 0.0005 14 0 0 0 0.00E+00 0.00E+00 - - - 4.3681 1 230117_WJC_METTL3_WT_vs_EV_F07.22297.22297.2 6.13E-06 26-Dec K.IFFIDPNER[166.11]PVTLY.H "sp|O95619|YETS4_HUMAN,tr|F8W1B9|F8W1B9_HUMAN,tr|F8VTR4|F8VTR4_HUMAN" 3 1732.9064 -1 63402 22297 2 1732.90476 867.4605 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 4.37 3974.1 - 1.06E+06 - - - -0.9337 - 2.339 0.479 - 276.9 1 1 0 -0.0016 14 0 0 0 0.00E+00 0.00E+00 - - - 4.7107 0.9429 230117_WJC_METTL3_WT_vs_EV_F07.22298.22298.2 0.0179 26-Oct R.GLLEESSFATLFPK[136.11].Y sp|Q13601|KRR1_HUMAN 1 1545.817 0.98 63403 22298 2 1545.80577 773.9158 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3974.1 - 984607 - - - -7.2719 - 1.866 0.368 - 174.7 1 2 0 -0.0112 14 0 0 0 6.68E+06 6.81E+06 - - - 3.3209 0.999 230117_WJC_METTL3_WT_vs_EV_F07.22300.22300.2 0.029 16-Sep K.IAILGFAFK.K sp|O60701|UGDH_HUMAN 1 978.5902 -1 63405 22300 2 978.589971 490.3024 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 8.75 3974.4 - 863495 - - - -0.2739 - 2.123 0.267 - 197 2 2 0 -0.0003 9 0 0 0 0.00E+00 0.00E+00 - - - 3.0565 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.22305.22305.2 0.006 16-Jul K.EVWDYVFFK[136.11].E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PRP1|A0A6I8PRP1_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 1239.6056 -1 63410 22305 2 1239.605923 620.8101 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.37 3975 - 329839 - - - 0.292 - 1.677 0.402 - 177.4 1 2 0 0.0004 9 0 0 0 0.00E+00 0.00E+00 - - - 3.5058 1 230117_WJC_METTL3_WT_vs_EV_F07.22308.22308.2 3.62E-09 17/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 6.1 63412 22308 2 1591.944581 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3975.4 - 3.83E+06 - - - -0.2626 - 3.014 0.626 - 653.4 1 2 0 -0.0004 15 0 0 0 4.78E+07 7.84E+06 - - - 6.3769 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22315.22315.2 0.209 18-Nov K.NIFAILQSVK.A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1131.6652 1.64 63419 22315 2 1131.665917 566.8399 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3975.8 - 4.34E+06 - - - 0.638 - 2.06 0.374 - 276.3 1 2 0 0.0007 10 0 0 0 2.53E+07 1.54E+07 - - - 3.8204 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22320.22320.2 0.604 18-Oct K.NIFAILQSVK[136.11].A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1139.6794 1.64 63424 22320 2 1139.680418 570.847 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3976.1 - 2.89E+06 - - - 0.8976 - 2.033 0.334 - 228.3 1 2 0 0.001 10 0 0 0 2.53E+07 1.54E+07 - - - 3.4881 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.22323.22323.2 0.0159 22-Sep K.IIDEDGLLNLIR.T "sp|P35251|RFC1_HUMAN,tr|H0Y8U4|H0Y8U4_HUMAN" 2 1382.7769 -1 63427 22323 2 1382.779551 692.3957 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 4.03 3976.3 - 2.07E+06 - - - 1.8955 - 1.938 0.244 - 203.5 1 2 0 0.0026 12 0 0 0 0.00E+00 0.00E+00 - - - 2.5833 0.9671 230117_WJC_METTL3_WT_vs_EV_F07.22325.22325.3 0.142 Sep-60 K.ILGEGEFGSVMEGNLK.Q "sp|Q12866|MERTK_HUMAN,tr|A0A087WZQ5|A0A087WZQ5_HUMAN,tr|E9PHX8|E9PHX8_HUMAN" 3 1678.8236 -1 63429 22325 3 1678.82993 560.6152 Tyrosine-protein kinase Mer OS=Homo sapiens OX=9606 GN=MERTK PE=1 SV=2 4.25 3976.5 - 2.02E+06 - - - 3.7568 - 1.26 0.202 - 48.5 1 2 0 0.0063 16 0 0 0 0.00E+00 0.00E+00 - - - 1.3834 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.22326.22326.2 0.000237 18-Jul R.DFVVGALILR.S sp|Q9NUD5|ZCHC3_HUMAN 1 1101.6546 -1 63430 22326 2 1101.654981 551.8346 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 5.84 3976.5 - 1.92E+06 - - - 0.3186 - 1.547 0.467 - 123.7 1 2 0 0.0004 10 0 0 0 0.00E+00 0.00E+00 - - - 3.708 1 230117_WJC_METTL3_WT_vs_EV_F07.22327.22327.3 7.89E-06 16/56 R.TVFRPPLDIYDVLIR.L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0C4DFX0|A0A0C4DFX0_HUMAN" 2 1816.0247 1.08 63431 22327 3 1816.025698 606.3488 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.63 3976.6 - 1.91E+06 - - - 0.5462 - 2.653 0.567 - 217.6 1 2 0 0.001 15 0 0 0 5.29E+06 4.90E+06 - - - 7.4071 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22329.22329.3 0.000227 13/56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 5.2 63432 22329 3 1591.947154 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3976.8 - 1.64E+06 - - - 1.3537 - 2.32 0.393 - 183.8 1 2 0 0.0022 15 0 0 0 1.85E+07 3.55E+06 - - - 5.1169 0.997 230117_WJC_METTL3_WT_vs_EV_F07.22330.22330.2 0.304 22-Nov K.IIDEDGLLNLIR[166.11].T "sp|P35251|RFC1_HUMAN,tr|H0Y8U4|H0Y8U4_HUMAN" 2 1392.7852 -1 63433 22330 2 1392.783837 697.3999 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 4.03 3977 - 471290 - - - -0.9786 - 1.878 0.211 - 163.5 1 2 0 -0.0014 12 0 0 0 0.00E+00 0.00E+00 - - - 2.2572 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22331.22331.2 0.197 18-Nov R.ILGLLDAYLK[136.11].T sp|P26641|EF1G_HUMAN 1 1125.6889 0.85 63434 22331 2 1125.690501 563.8517 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3977 - 2.14E+07 - - - 1.4249 - 2.261 0.352 - 293.8 1 2 0 0.0016 10 0 0 0 3.94E+07 4.61E+07 - - - 3.9175 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22332.22332.2 0.00145 18-Dec R.ILGLLDAYLK.T sp|P26641|EF1G_HUMAN 1 1117.6747 0.85 63435 22332 2 1117.676641 559.8446 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3977 - 1.77E+07 - - - 1.7393 - 2.559 0.386 - 358 1 2 0 0.0019 10 0 0 0 3.94E+07 4.61E+07 - - - 4.5141 1 230117_WJC_METTL3_WT_vs_EV_F07.22334.22334.3 8.44E-07 17/44 K.LR[166.11]EC[160.03]LPLIIFLR[166.11].N sp|P62701|RS4X_HUMAN 1 1561.9281 0.85 63437 22334 3 1561.930354 521.65 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3977.1 - 4.75E+06 - - - 1.4239 - 3.15 0.54 - 574.4 1 2 1 0.0022 12 0 0 0 3.19E+07 3.74E+07 - - - 7.7403 0.9977 230117_WJC_METTL3_WT_vs_EV_F07.22335.22335.3 7.39E-08 17/44 K.LREC[160.03]LPLIIFLR.N sp|P62701|RS4X_HUMAN 1 1541.9116 0.85 63438 22335 3 1541.913686 514.9778 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3977.2 - 3.74E+06 - - - 1.3594 - 3.151 0.507 - 623 1 2 1 0.0021 12 0 0 0 3.15E+07 3.70E+07 - - - 7.3733 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22336.22336.3 6.66E-07 13/60 K.LPIVNEDDELVAIIAR.T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1778.9778 1.53 63439 22336 3 1778.982114 593.9999 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3977.2 - 1.92E+06 - - - 2.4166 - 2.415 0.49 - 216.8 1 2 0 0.0043 16 0 0 0 4.93E+06 3.23E+06 - - - 6.2641 1 230117_WJC_METTL3_WT_vs_EV_F07.22339.22339.2 2.18E-09 21/30 K.LPIVNEDDELVAIIAR.T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1778.9778 -1 63442 22339 2 1778.977883 890.4962 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3977.5 - 1.27E+06 - - - 0.0382 - 3.978 0.679 - 1428.2 1 2 0 0.0001 16 0 0 0 0.00E+00 0.00E+00 - - - 7.4508 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22341.22341.2 2.92E-05 20-Sep R.EVTPFFIIYC[160.03]R.A sp|Q02413|DSG1_HUMAN 1 1443.7221 999 63444 22341 2 1443.725141 722.8683 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 6.09 3977.7 - 984290 - - - 2.1355 - 2.044 0.443 - 340.3 1 2 0 0.0031 11 0 0 0 3.88E+06 0.00E+00 - - - 4.246 1 230117_WJC_METTL3_WT_vs_EV_F07.22344.22344.2 6.99E-05 16/24 K.NPILWNVADVVIK.F "sp|P04844|RPN2_HUMAN,tr|H0Y5M1|H0Y5M1_HUMAN,tr|Q5JYR3|Q5JYR3_HUMAN" 3 1479.8449 -1 63447 22344 2 1479.846411 740.9298 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 5.84 3978.1 - 924328 - - - 0.9873 - 2.677 0.53 - 526.3 1 2 0 0.0015 13 0 0 0 0.00E+00 0.00E+00 - - - 5.4824 1 230117_WJC_METTL3_WT_vs_EV_F07.22346.22346.2 4.34E-07 16/26 K.LLSDFLDSEVSELR.T sp|Q9BPX3|CND3_HUMAN 1 1621.8199 -1 63449 22346 2 1621.824273 811.9172 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 3.92 3978.3 - 809212 - - - 2.6859 - 3.083 0.561 - 937.3 1 2 0 0.0044 14 0 0 0 0.00E+00 0.00E+00 - - - 6.0086 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.22347.22347.2 0.0733 16-Sep R.VPLILNLIR.H sp|Q15648|MED1_HUMAN 1 1049.6961 -1 63450 22347 2 1049.697234 525.8553 Mediator of RNA polymerase II transcription subunit 1 OS=Homo sapiens OX=9606 GN=MED1 PE=1 SV=4 9.72 3978.5 - 752114 - - - 1.0794 - 1.766 0.355 - 199.6 1 2 0 0.0011 9 0 0 0 0.00E+00 0.00E+00 - - - 3.308 1 230117_WJC_METTL3_WT_vs_EV_F07.22348.22348.2 5.26E-09 17/30 K.LPIVNEDDELVAIIAR[166.11].T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1788.9861 1.88 63451 22348 2 1788.986975 895.5003 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3978.6 - 731265 - - - 0.4975 - 3.404 0.663 - 724 1 2 0 0.0009 16 0 0 0 5.13E+06 2.74E+06 - - - 6.9492 1 230117_WJC_METTL3_WT_vs_EV_F07.22352.22352.2 2.94E-06 15/22 R.LGPLLDILADSR.H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1281.7293 1.55 63454 22352 2 1281.730331 641.8719 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3979 - 6.66E+06 - - - 0.8418 - 2.779 0.538 - 919.1 1 2 0 0.0011 12 0 0 0 2.86E+07 1.85E+07 - - - 5.7036 0.8572 230117_WJC_METTL3_WT_vs_EV_F07.22353.22353.2 1.52 18-Oct K.VSQEILELLN.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1156.634 - 63455 22353 2 1156.634948 579.3243 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.79 3979 - 6.41E+06 - - - 0.8594 - 1.945 0.112 - 249.1 1 1 0 0.001 10 0 0 0 - - - - - 1.7249 1 230117_WJC_METTL3_WT_vs_EV_F07.22354.22354.2 1.07E-05 15/22 R.LGPLLDILADSR[166.11].H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1291.7375 1.55 63456 22354 2 1291.739124 646.876 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3979.1 - 4.35E+06 - - - 1.2402 - 2.942 0.515 - 992.3 1 2 0 0.0016 12 0 0 0 2.86E+07 1.85E+07 - - - 5.6836 0.9693 230117_WJC_METTL3_WT_vs_EV_F07.22356.22356.2 0.0112 14-Aug K.KEDLVFIF.W "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 1009.5484 -1 63458 22356 2 1009.549207 505.7815 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.37 3979.2 - 3.17E+06 - - - 0.7657 - 1.544 0.453 - 181.6 1 1 0 0.0008 8 0 0 0 0.00E+00 0.00E+00 - - - 3.6967 1 230117_WJC_METTL3_WT_vs_EV_F07.22357.22357.2 6.50E-07 13/22 K.VNFLPEIITLSK.E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1372.7966 0.97 63459 22357 2 1372.798599 687.4056 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.97 3979.3 - 2.56E+06 - - - 1.454 - 2.282 0.524 - 486.8 1 2 0 0.002 12 0 0 0 8.29E+06 8.50E+06 - - - 5.0815 1 230117_WJC_METTL3_WT_vs_EV_F07.22358.22358.2 9.21E-06 22-Dec K.VNFLPEIITLSK[136.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1380.8108 0.88 63460 22358 2 1380.812284 691.4127 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.97 3979.3 - 2.19E+06 - - - 1.0726 - 2.146 0.579 - 428.7 1 2 0 0.0015 12 0 0 0 8.29E+06 9.39E+06 - - - 5.3262 1 230117_WJC_METTL3_WT_vs_EV_F07.22360.22360.2 3.60E-09 15/24 R.SDFFLEGPFMPPR.M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1538.7228 2.06 63462 22360 2 1538.722278 770.3687 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3979.5 - 1.19E+06 - - - -0.3301 - 3.056 0.503 - 771.4 1 2 0 -0.0005 13 0 0 0 7.86E+06 3.82E+06 - - - 5.6231 0.9954 230117_WJC_METTL3_WT_vs_EV_F07.22364.22364.3 0.157 13/60 K.LPIVNEDDELVAIIAR[166.11].T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1788.9861 1.53 63466 22364 3 1788.99365 597.336 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3979.9 - 986936 - - - 4.2287 - 2.196 0.221 - 223.7 1 2 0 0.0076 16 0 0 0 4.93E+06 3.23E+06 - - - 3.0202 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.22365.22365.2 0.00546 18-Jul K.GGPGLPLPPL.- sp|Q9H7N4|SFR19_HUMAN 1 916.5382 - 63467 22365 2 916.538353 459.2764 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.52 3980 - 881821 - - - 0.1637 - 1.49 0.376 - 158.5 1 2 0 0.0001 10 0 0 0 - - - - - 2.9312 0.8612 230117_WJC_METTL3_WT_vs_EV_F07.22366.22366.2 0.0232 14-Aug K.K[136.11]EDLVFIF.W "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 1017.5626 -1 63468 22366 2 1017.564687 509.7886 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.37 3980.1 - 840803 - - - 2.0176 - 1.186 0.305 - 141.5 1 1 0 0.0021 8 0 0 0 0.00E+00 0.00E+00 - - - 1.8076 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22367.22367.2 0.00253 20-Sep R.FLIPVLNGLEK.K "sp|Q92797|SYMPK_HUMAN,tr|A0A087WUE9|A0A087WUE9_HUMAN" 2 1241.7384 1.56 63469 22367 2 1241.740313 621.8765 Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2 6 3980.3 - 686507 - - - 1.5728 - 1.802 0.375 - 200.9 1 2 0 0.002 11 0 0 0 3.17E+06 2.03E+06 - - - 3.4032 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22368.22368.2 0.548 15/22 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 0.99 63470 22368 2 1344.8657 673.4385 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3980.4 - 652436 - - - 2.4203 - 2.469 0.359 - 768 1 2 0 0.0033 12 0 0 0 1.06E+08 1.06E+08 - - - 4.0696 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.22369.22369.2 0.0304 14/22 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 0.99 63471 22369 2 1336.848058 669.4314 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3980.5 - 581112 - - - -0.1399 - 2.459 0.365 - 695.2 1 2 0 -0.0002 12 0 0 0 1.06E+08 1.06E+08 - - - 4.1042 0.9959 230117_WJC_METTL3_WT_vs_EV_F07.22372.22372.2 0.0331 24-Jun R.EYMSPDIALLYLK.H sp|Q7RTY7|OVCH1_HUMAN 1 1554.8004 3.21 63473 22372 2 1554.803551 778.4075 Ovochymase-1 OS=Homo sapiens OX=9606 GN=OVCH1 PE=2 SV=2 4.37 3980.9 - 591164 - - - 2.0472 - 1.185 0.237 - 68 1 2 0 0.0032 13 0 0 0 4.30E+06 1.34E+06 - - - 1.2261 0.9503 230117_WJC_METTL3_WT_vs_EV_F07.22373.22373.2 0.054 14-Jul R.EC[160.03]LNLWGY.E sp|Q86U44|MTA70_HUMAN 1 1053.459 - 63474 22373 2 1053.460074 527.7368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3981 - 2.06E+06 - - - 1.0508 - 1.52 0.349 - 204.5 1 1 0 0.0011 8 0 0 0 - - - - - 2.8812 0.956 230117_WJC_METTL3_WT_vs_EV_F07.22374.22374.2 0.769 20-Aug R.LLDMDGIIVEK.Q sp|Q14152|EIF3A_HUMAN 1 1244.6686 2.97 63475 22374 2 1244.66616 623.3416 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.03 3981 - 1.62E+06 - - - -1.9804 - 1.439 0.071 - 159 1 2 0 -0.0025 11 0 0 0 4.73E+06 1.59E+06 - - - 0.5492 0.9729 230117_WJC_METTL3_WT_vs_EV_F07.22378.22378.2 1.24E-05 20-Aug R.FSDHVALLSVF.Q sp|Q08211|DHX9_HUMAN 1 1233.6394 - 63479 22378 2 1233.640759 617.827 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.08 3981.4 - 942157 - - - 1.1227 - 1.739 0.443 - 190 1 1 0 0.0014 11 0 0 0 - - - - - 3.8094 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22380.22380.2 0.00409 18-Nov K.LASDLLEWIR.R "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|G3V2W4|G3V2W4_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 14 1214.6659 1.36 63481 22380 2 1214.666911 608.3402 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.37 3981.7 - 899401 - - - 0.8134 - 2.465 0.406 - 464.6 1 2 0 0.001 10 0 0 0 8.97E+06 6.61E+06 - - - 4.5577 0.997 230117_WJC_METTL3_WT_vs_EV_F07.22382.22382.2 0.0612 16-Aug R.QLYLPMLFK.V "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN" 13 1151.6413 -1 63483 22382 2 1151.642778 576.8279 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3981.8 - 864491 - - - 1.2938 - 1.457 0.167 - 138.6 1 2 0 0.0015 9 0 0 0 0.00E+00 0.00E+00 - - - 1.3629 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22383.22383.2 0.000128 22-Oct R.VLGLLGALDPYK.H sp|P42345|MTOR_HUMAN 1 1257.7333 0.99 63484 22383 2 1257.733734 629.8739 Serine\threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 5.81 3981.9 - 863291 - - - 0.3649 - 2.067 0.463 - 262.8 1 2 0 0.0005 12 0 0 0 3.98E+06 4.00E+06 - - - 4.3711 1 230117_WJC_METTL3_WT_vs_EV_F07.22386.22386.2 8.75E-10 18/30 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 -1 63487 22386 2 1751.871255 876.9399 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3982.3 - 566343 - - - 3.4831 - 3.646 0.633 - 939 1 2 0 0.0061 16 0 0 0 0.00E+00 0.00E+00 - - - 6.8949 0.9641 230117_WJC_METTL3_WT_vs_EV_F07.22390.22390.2 3.81 24-Aug R.GNSIIMLEALER[166.11]V.- "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1453.7838 -1 63491 22390 2 1453.785599 727.8992 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3982.8 - 455009 - - - 1.2237 - 1.283 0.01 - 132.3 2 2 0 0.0018 13 0 0 0 0.00E+00 0.00E+00 - - - -0.3806 1 230117_WJC_METTL3_WT_vs_EV_F07.22394.22394.3 8.12E-09 15/60 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 -1 63494 22394 3 1751.868138 584.9623 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3983.2 - 5.12E+06 - - - 1.7039 - 3.185 0.545 - 386.8 1 2 0 0.003 16 0 0 0 0.00E+00 0.00E+00 - - - 7.5878 1 230117_WJC_METTL3_WT_vs_EV_F07.22396.22396.2 5.16E-07 14/20 K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 -1 63496 22396 2 1315.787387 658.9005 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3983.3 - 3.49E+06 - - - 0.7706 - 2.187 0.606 - 707 1 2 0 0.001 11 0 0 0 0.00E+00 0.00E+00 - - - 5.6335 1 230117_WJC_METTL3_WT_vs_EV_F07.22397.22397.2 1.18E-05 13/20 K.TLSYLLPLLQR[166.11].L sp|Q9NUL7|DDX28_HUMAN 1 1325.7946 1.11 63497 22397 2 1325.796828 663.9046 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3983.3 - 3.35E+06 - - - 1.6481 - 2.108 0.554 - 567.6 1 2 0 0.0022 11 0 0 0 1.79E+07 1.61E+07 - - - 5.1496 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22398.22398.2 0.268 18-Dec K.LASDLLEWIR[166.11].R "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|G3V2W4|G3V2W4_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 14 1224.6742 -1 63498 22398 2 1224.675551 613.3444 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.37 3983.4 - 2.99E+06 - - - 1.1089 - 2.582 0.251 - 580.3 1 2 0 0.0014 10 0 0 0 0.00E+00 0.00E+00 - - - 3.5422 1 230117_WJC_METTL3_WT_vs_EV_F07.22399.22399.2 8.39E-11 16/30 K.VGEVTYVELLMDAEGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1759.8794 -1 63499 22399 2 1759.881361 880.947 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3983.4 - 2.90E+06 - - - 1.141 - 3.257 0.689 - 762.6 1 2 0 0.002 16 0 0 0 0.00E+00 0.00E+00 - - - 7.0324 1 230117_WJC_METTL3_WT_vs_EV_F07.22400.22400.2 5.09E-07 13/22 R.YLDFSSIITEVR.A sp|Q8N1N4|K2C78_HUMAN 1 1441.7453 -1 63500 22400 2 1441.748855 721.8799 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.37 3983.5 - 2.77E+06 - - - 2.4685 - 2.606 0.597 - 575.6 1 2 0 0.0036 12 0 0 0 0.00E+00 0.00E+00 - - - 5.9695 1 230117_WJC_METTL3_WT_vs_EV_F07.22401.22401.2 3.43E-07 16/28 K.LGLLGLANSLAIEGR.K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1495.8722 -1 63501 22401 2 1495.875491 748.9434 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3983.6 - 2.22E+06 - - - 2.1813 - 3.098 0.591 - 977.3 1 2 0 0.0033 15 0 0 0 0.00E+00 0.00E+00 - - - 6.1851 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22402.22402.3 5.65E-05 14/44 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 0.96 63502 22402 3 1344.863827 449.2948 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3983.7 - 1.71E+06 - - - 1.0276 - 2.396 0.452 - 271.3 1 2 0 0.0014 12 0 0 0 6.65E+06 6.94E+06 - - - 6.001 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.22403.22403.2 0.00411 18-Aug K.VLVYELLLGK.G sp|Q96P11|NSUN5_HUMAN 1 1145.706 -1 63503 22403 2 1145.708663 573.8603 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 5.97 3983.7 - 1.64E+06 - - - 2.3269 - 1.742 0.356 - 169 1 2 0 0.0027 10 0 0 0 0.00E+00 0.00E+00 - - - 3.2188 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22404.22404.3 0.000142 14/44 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 0.96 63504 22404 3 1336.849633 446.6234 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3983.8 - 1.52E+06 - - - 1.0383 - 2.417 0.458 - 269.2 1 2 0 0.0014 12 0 0 0 6.65E+06 6.94E+06 - - - 6.0921 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22407.22407.2 1.05E-05 20-Nov K.EYPFILDAFQR.E sp|P42285|MTREX_HUMAN 1 1397.698 1.37 63507 22407 2 1397.700669 699.8563 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 3984.1 - 1.09E+06 - - - 1.9439 - 2.042 0.441 - 443.5 1 2 0 0.0027 11 0 0 0 7.26E+06 5.30E+06 - - - 4.2287 1 230117_WJC_METTL3_WT_vs_EV_F07.22408.22408.2 5.37E-08 16/26 R.LLNNAFEELVAFQR.A "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1662.873 -1 63508 22408 2 1662.873338 832.4438 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.53 3984.2 - 1.05E+06 - - - 0.2297 - 3.203 0.635 - 1056.8 1 2 0 0.0004 14 0 0 0 0.00E+00 0.00E+00 - - - 6.6522 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.22409.22409.2 0.00168 20-Oct K.EYPFILDAFQR[166.11].E sp|P42285|MTREX_HUMAN 1 1407.7062 1.37 63509 22409 2 1407.710428 704.8604 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 3984.3 - 933558 - - - 2.9878 - 2.053 0.484 - 449 1 2 0 0.0042 11 0 0 0 7.26E+06 5.30E+06 - - - 4.5604 0.9984 230117_WJC_METTL3_WT_vs_EV_F07.22410.22410.3 0.0436 Oct-56 K.LGLLGLANSLAIEGR.K "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1495.8722 -1 63510 22410 3 1495.874239 499.6314 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6 3984.4 - 811994 - - - 1.3444 - 1.769 0.251 - 153.6 1 2 0 0.002 15 0 0 0 0.00E+00 0.00E+00 - - - 2.8263 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22414.22414.3 0.000244 13/40 K.TLSYLLPLLQR[166.11].L sp|Q9NUL7|DDX28_HUMAN 1 1325.7946 -1 63513 22414 3 1325.796009 442.9388 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3984.9 - 1.53E+06 - - - 1.0303 - 2.376 0.395 - 315.2 1 2 0 0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 5.402 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22416.22416.3 1.40E-05 13/52 R.LLNNAFEELVAFQR.A "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1662.873 -1 63515 22416 3 1662.87218 555.2983 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.53 3984.9 - 3.83E+06 - - - -0.4667 - 2.145 0.507 - 204.6 1 2 0 -0.0008 14 0 0 0 0.00E+00 0.00E+00 - - - 6.2204 1 230117_WJC_METTL3_WT_vs_EV_F07.22419.22419.2 9.68E-05 13/22 R.NLQNLLILTAIK[136.11].A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1360.8533 1.04 63518 22419 2 1360.852972 681.4339 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3985.2 - 1.62E+06 - - - -0.2682 - 2.336 0.544 - 504.3 1 2 0 -0.0004 12 0 0 0 2.73E+07 2.62E+07 - - - 5.2913 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22420.22420.2 0.00672 18-Nov K.LNMILVQILK.Q "sp|O14980|XPO1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 10 1183.7363 -1 63519 22420 2 1183.738298 592.8754 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3985.3 - 1.59E+06 - - - 1.7293 - 2.343 0.413 - 366.1 1 2 0 0.002 10 0 0 0 0.00E+00 0.00E+00 - - - 4.4674 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22422.22422.2 2.66E-05 18-Nov R.SPNDLLALFR.Y "sp|Q92626|PXDN_HUMAN,tr|H7C1W1|H7C1W1_HUMAN" 2 1144.6241 0.16 63521 22422 2 1144.626553 573.3193 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 5.55 3985.4 - 1.21E+06 - - - 2.1798 - 2.132 0.406 - 488.6 1 2 0 0.0025 10 0 0 0 4.11E+06 2.62E+07 - - - 4.1521 0.9998 230117_WJC_METTL3_WT_vs_EV_F07.22423.22423.3 1.01E-06 Dec-40 K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 -1 63522 22423 3 1315.787813 439.6027 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3985.6 - 1.17E+06 - - - 1.0944 - 2.291 0.363 - 278.9 1 2 0 0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 4.9417 1 230117_WJC_METTL3_WT_vs_EV_F07.22424.22424.2 5.49E-07 15/28 K.GVFVQSVLPYFVATK.L "sp|Q53GQ0|DHB12_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN" 2 1653.913 -1 63523 22424 2 1653.911303 827.9638 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 8.59 3985.6 - 1.06E+06 - - - -1.0442 - 2.664 0.595 - 510.6 1 2 0 -0.0017 15 0 0 0 0.00E+00 0.00E+00 - - - 5.8441 1 230117_WJC_METTL3_WT_vs_EV_F07.22426.22426.2 7.39E-08 18/28 K.LTILQSLGDPLYYGK.L "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 1679.9134 -1 63525 22426 2 1679.917951 840.964 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.83 3985.8 - 874757 - - - 2.6948 - 3.095 0.566 - 1034.5 1 2 0 0.0045 15 0 0 0 0.00E+00 0.00E+00 - - - 5.9977 1 230117_WJC_METTL3_WT_vs_EV_F07.22428.22428.2 1.83E-10 17/24 K.APDEETLIALLAH.A "sp|Q9Y3E5|PTH2_HUMAN,tr|J3KQ48|J3KQ48_HUMAN" 2 1391.7296 - 63527 22428 2 1391.732596 696.8721 "Peptidyl-tRNA hydrolase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PTRH2 PE=1 SV=1" 4.13 3986 - 795894 - - - 2.1197 - 3.215 0.707 - 748.3 1 1 0 0.0029 13 0 0 0 - - - - - 7.2592 1 230117_WJC_METTL3_WT_vs_EV_F07.22429.22429.2 7.22E-06 26-Nov K.ELAEEGVLEEAEFY.N sp|Q14681|KCTD2_HUMAN 1 1626.7301 - 63528 22429 2 1626.731354 814.3723 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 3.46 3986.2 - 777820 - - - 0.7715 - 2.181 0.522 - 185 1 1 0 0.0013 14 0 0 0 - - - - - 4.8529 1 230117_WJC_METTL3_WT_vs_EV_F07.22431.22431.2 1.70E-06 14/26 R.ISLPLPNFSSLNLR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1569.8879 1.55 63530 22431 2 1569.891907 785.9512 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3986.4 - 640638 - - - 2.5664 - 2.615 0.598 - 542.7 1 2 0 0.004 14 0 0 0 8.40E+06 5.43E+06 - - - 5.8688 0.993 230117_WJC_METTL3_WT_vs_EV_F07.22432.22432.2 0.425 22-Nov K.IILNTAVAEFFK.S "sp|Q9H9A5|CNO10_HUMAN,tr|H7C1X9|H7C1X9_HUMAN" 2 1364.7704 -1 63531 22432 2 1364.774277 683.3925 CCR4-NOT transcription complex subunit 10 OS=Homo sapiens OX=9606 GN=CNOT10 PE=1 SV=1 6 3986.6 - 723850 - - - 2.8496 - 1.505 0.135 - 203 1 2 0 0.0039 12 0 0 0 0.00E+00 0.00E+00 - - - 1.1125 1 230117_WJC_METTL3_WT_vs_EV_F07.22435.22435.2 8.90E-08 14/32 R.AALGPLVTGLYDVQAFK.F "sp|P11172|UMPS_HUMAN,tr|F2Z303|F2Z303_HUMAN,tr|F2Z3P2|F2Z3P2_HUMAN,tr|F8WDG4|F8WDG4_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 5 1761.9665 2.77 63533 22435 2 1761.970058 881.9905 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 5.88 3986.9 - 577230 - - - 2.0068 - 2.685 0.564 - 397.7 1 2 0 0.0035 17 0 0 0 2.61E+06 9.43E+05 - - - 5.6339 1 230117_WJC_METTL3_WT_vs_EV_F07.22436.22436.2 0.000257 22-Dec R.NLQNLLILTAIK.A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1352.8391 1.04 63534 22436 2 1352.840807 677.4268 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3987 - 1.53E+07 - - - 1.2344 - 2.407 0.567 - 424.9 1 2 0 0.0017 12 0 0 0 2.73E+07 2.62E+07 - - - 5.5395 1 230117_WJC_METTL3_WT_vs_EV_F07.22438.22438.2 2.71E-06 18-Nov K.FDTIYQILLK.K "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 1252.7067 -1 63536 22438 2 1252.709397 627.3606 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 5.83 3987.1 - 2.53E+06 - - - 2.133 - 2.281 0.532 - 402.7 1 2 0 0.0027 10 0 0 0 0.00E+00 0.00E+00 - - - 5.2713 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22441.22441.3 4.21E-05 Nov-44 R.NLQNLLILTAIK.A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1352.8391 -1 63539 22441 3 1352.840161 451.9537 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3987.3 - 2.01E+06 - - - 0.7569 - 2.449 0.468 - 262.6 1 2 0 0.001 12 0 0 0 0.00E+00 0.00E+00 - - - 6.2401 1 230117_WJC_METTL3_WT_vs_EV_F07.22442.22442.2 6.41E-05 14/22 K.LGTLSALDILIK[136.11].N "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1263.7893 -1 63540 22442 2 1263.791074 632.9019 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 5.84 3987.4 - 1.60E+06 - - - 1.3729 - 2.277 0.463 - 452.7 1 2 0 0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 4.6253 0.9561 230117_WJC_METTL3_WT_vs_EV_F07.22447.22447.3 0.276 Nov-56 K.GVFVQSVLPYFVATK.L "sp|Q53GQ0|DHB12_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN" 2 1653.913 -1 63545 22447 3 1653.922023 552.3116 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 8.59 3988 - 1.03E+06 - - - 5.4374 - 1.75 0.175 - 130.7 1 2 0 0.009 15 0 0 0 0.00E+00 0.00E+00 - - - 1.9488 1 230117_WJC_METTL3_WT_vs_EV_F07.22449.22449.3 6.17E-07 17/64 R.AFLQGGQEATDIALLLR.D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1814.989 -1 63547 22449 3 1814.992242 606.0036 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3988.2 - 912373 - - - 1.7598 - 3.102 0.532 - 392.4 1 2 0 0.0032 17 0 0 0 0.00E+00 0.00E+00 - - - 7.3303 1 230117_WJC_METTL3_WT_vs_EV_F07.22451.22451.3 5.98E-09 16/52 R.HPYFYAPELLFFAK.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 1741.8868 31.26 63549 22451 3 1741.890903 581.6362 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6.75 3988.4 - 888333 - - - 2.3469 - 3.132 0.608 - 471.7 1 2 0 0.0041 14 0 0 0 3.52E+06 1.13E+05 - - - 8.3515 1 230117_WJC_METTL3_WT_vs_EV_F07.22452.22452.2 3.73E-10 15/26 K.LPVDFSNIPTYLLK.D "sp|Q9NXR7|BABA2_HUMAN,tr|F8W733|F8W733_HUMAN" 2 1618.897 -1 63550 22452 2 1618.897737 810.4558 BRISC and BRCA1-A complex member 2 OS=Homo sapiens OX=9606 GN=BABAM2 PE=1 SV=2 5.83 3988.5 - 808915 - - - 0.4275 - 3.079 0.599 - 666.4 1 2 0 0.0007 14 0 0 0 0.00E+00 0.00E+00 - - - 6.2871 0.9378 230117_WJC_METTL3_WT_vs_EV_F07.22457.22457.2 0.00333 18-Jul E.QEEDISSLIR.S sp|P78527|PRKDC_HUMAN 1 1188.5986 7.88 63554 22457 2 1188.600294 595.3066 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.14 3989 - 1.23E+07 - - - 1.3983 - 1.485 0.33 - 153.5 1 1 0 0.0017 10 0 0 0 2.87E+07 3.64E+06 - - - 2.5816 1 230117_WJC_METTL3_WT_vs_EV_F07.22459.22459.2 1.51E-05 13/22 K.TSDLIVLGLPWK[136.11].T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1348.7846 -1 63556 22459 2 1348.7864 675.3996 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3989.1 - 5.82E+06 - - - 1.3434 - 2.323 0.527 - 607.3 1 2 0 0.0018 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1506 1 230117_WJC_METTL3_WT_vs_EV_F07.22461.22461.2 1.31E-06 16/26 R.VISGVLQLGNIVFK[136.11].K sp|P35579|MYH9_HUMAN 1 1493.9061 -1 63558 22461 2 1493.907752 747.9603 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.72 3989.2 - 3.07E+06 - - - 1.1052 - 2.952 0.606 - 605 1 2 0 0.0017 14 0 0 0 0.00E+00 0.00E+00 - - - 6.2328 0.9988 230117_WJC_METTL3_WT_vs_EV_F07.22463.22463.2 0.000749 20-Dec R.FILNLPTFSVR[166.11].L "sp|P49721|PSB2_HUMAN,tr|A0A087WVV1|A0A087WVV1_HUMAN" 2 1315.7528 -1 63560 22463 2 1315.75172 658.8837 Proteasome subunit beta type-2 OS=Homo sapiens OX=9606 GN=PSMB2 PE=1 SV=1 9.75 3989.3 - 2.12E+06 - - - -0.8041 - 2.256 0.272 - 504.2 1 2 0 -0.0011 11 0 0 0 0.00E+00 0.00E+00 - - - 3.2506 1 230117_WJC_METTL3_WT_vs_EV_F07.22466.22466.2 1.00E-09 18/32 R.AFLQGGQEATDIALLLR.D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1814.989 -1 63563 22466 2 1814.991591 908.5018 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3989.6 - 1.55E+06 - - - 1.4011 - 3.685 0.65 - 1107.7 1 2 0 0.0025 17 0 0 0 0.00E+00 0.00E+00 - - - 7.0477 1 230117_WJC_METTL3_WT_vs_EV_F07.22467.22467.2 5.69E-05 22-Dec K.NVLITDFFGSVR[166.11].K "sp|Q92643|GPI8_HUMAN,tr|B1AK81|B1AK81_HUMAN,tr|A6NEM5|A6NEM5_HUMAN" 3 1376.7328 -1 63564 22467 2 1376.735925 689.3737 GPI-anchor transamidase OS=Homo sapiens OX=9606 GN=PIGK PE=1 SV=2 5.84 3989.7 - 1.47E+06 - - - 2.2909 - 2.468 0.463 - 534.2 1 2 0 0.0032 12 0 0 0 0.00E+00 0.00E+00 - - - 4.8367 1 230117_WJC_METTL3_WT_vs_EV_F07.22470.22470.2 3.79E-07 16/26 R.ISLPLPNFSSLNLR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1579.8961 1.52 63567 22470 2 1579.896535 790.9554 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3990 - 1.07E+06 - - - 0.245 - 2.705 0.566 - 657.5 1 2 0 0.0004 14 0 0 0 8.26E+06 5.43E+06 - - - 5.7185 1 230117_WJC_METTL3_WT_vs_EV_F07.22471.22471.2 7.59E-07 16/24 R.DPTYFGPVLNYLR[166.11].H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1563.7961 0.9 63568 22471 2 1563.801513 782.9053 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3990.1 - 994292 - - - 3.4621 - 2.947 0.592 - 951.9 1 2 0 0.0054 13 0 0 0 6.36E+06 7.09E+06 - - - 6.1857 1 230117_WJC_METTL3_WT_vs_EV_F07.22472.22472.2 4.87E-11 14/32 K.LFEMVLGPAAYNVPLPK.K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1858.0063 -1 63569 22472 2 1858.013255 930.0104 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6 3990.2 - 946675 - - - 3.7551 - 2.892 0.601 - 589.3 1 2 0 0.007 17 0 0 0 0.00E+00 0.00E+00 - - - 6.0886 1 230117_WJC_METTL3_WT_vs_EV_F07.22474.22474.3 7.23E-05 22/72 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 63571 22474 3 1911.184167 638.0676 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3990.5 - 723548 - - - 1.7241 - 3.588 0.535 - 599.8 1 2 0 0.0033 19 0 0 0 0.00E+00 0.00E+00 - - - 7.6426 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.22477.22477.2 0.000317 22-Nov R.SQALIEELLLYK[136.11].R sp|Q5VT52|RPRD2_HUMAN 1 1426.8163 -1 63573 22477 2 1426.815542 714.4154 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3990.9 - 741743 - - - -0.5186 - 1.76 0.39 - 254.6 1 2 0 -0.0007 12 0 0 0 0.00E+00 0.00E+00 - - - 3.4087 0.8631 230117_WJC_METTL3_WT_vs_EV_F07.22478.22478.2 0.0402 18-Jun K.VEDLTFTSPF.C "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1154.5496 - 63574 22478 2 1154.551507 578.2821 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 3.67 3991 - 6.98E+06 - - - 1.6898 - 1.152 0.313 - 100.8 1 1 0 0.002 10 0 0 0 - - - - - 1.7472 0.9277 230117_WJC_METTL3_WT_vs_EV_F07.22479.22479.2 1.94 18-Apr R.C[160.03]FSTTLLYC[160.03]R.K sp|P60893|GPR85_HUMAN 1 1319.6002 -1 63575 22479 2 1319.598416 660.8074 Probable G-protein coupled receptor 85 OS=Homo sapiens OX=9606 GN=GPR85 PE=1 SV=1 8.06 3991.1 - 2.72E+06 - - - -1.3739 - 1.1 0.114 - 44.2 3 2 0 -0.0018 10 0 0 0 0.00E+00 0.00E+00 - - - -0.0647 1 230117_WJC_METTL3_WT_vs_EV_F07.22483.22483.2 3.23E-05 20-Nov R.VLDLVEVLVTK[136.11].Q "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1234.7628 -1 63579 22483 2 1234.764269 618.3887 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.37 3991.3 - 1.46E+06 - - - 1.1978 - 2.36 0.611 - 316.6 1 2 0 0.0015 11 0 0 0 0.00E+00 0.00E+00 - - - 5.8763 1 230117_WJC_METTL3_WT_vs_EV_F07.22485.22485.2 2.92E-05 26-Dec K.TLAESALQLLYTAK.E sp|Q9Y490|TLN1_HUMAN 1 1520.845 -1 63581 22485 2 1520.847081 761.4298 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.66 3991.5 - 1.31E+06 - - - 1.3617 - 2.135 0.506 - 327.8 1 2 0 0.0021 14 0 0 0 0.00E+00 0.00E+00 - - - 4.681 1 230117_WJC_METTL3_WT_vs_EV_F07.22488.22488.2 0.0147 15/36 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 63584 22488 2 1911.182795 956.5977 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3991.8 - 1.06E+06 - - - 1.0062 - 2.542 0.507 - 441.5 1 2 0 0.0019 19 0 0 0 0.00E+00 0.00E+00 - - - 5.0788 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.22489.22489.2 0.00142 26-Oct K.TLAESALQLLYTAK[136.11].E sp|Q9Y490|TLN1_HUMAN 1 1528.8592 -1 63585 22489 2 1528.857627 765.4369 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.66 3991.9 - 1.02E+06 - - - -1.0354 - 1.91 0.445 - 189.9 1 2 0 -0.0016 14 0 0 0 0.00E+00 0.00E+00 - - - 3.9511 0.9998 230117_WJC_METTL3_WT_vs_EV_F07.22490.22490.3 0.000106 13/48 R.GNTAAYLLYAFTR.L sp|P54136|SYRC_HUMAN 1 1459.746 -1 63586 22490 3 1459.747168 487.5893 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.59 3991.9 - 960819 - - - 0.8241 - 2.124 0.365 - 178.4 1 2 0 0.0012 13 0 0 0 0.00E+00 0.00E+00 - - - 4.6515 0.9658 230117_WJC_METTL3_WT_vs_EV_F07.22491.22491.2 0.789 22-Jul R.SQALIEELLLYK.R sp|Q5VT52|RPRD2_HUMAN 1 1418.8021 -1 63587 22491 2 1418.803072 710.4083 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3992 - 869461 - - - 0.6978 - 1.105 0.073 - 36.6 2 2 0 0.001 12 0 0 0 0.00E+00 0.00E+00 - - - -0.2919 1 230117_WJC_METTL3_WT_vs_EV_F07.22493.22493.2 4.97E-07 14/24 R.DPTYFGPVLNYLR.H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1553.7878 0.9 63589 22493 2 1553.788345 777.9012 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3992.3 - 856534 - - - 0.3321 - 2.586 0.574 - 741.4 1 2 0 0.0005 13 0 0 0 6.36E+06 7.09E+06 - - - 5.7189 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22495.22495.3 0.00442 Sep-48 R.GNTAAYLLYAFTR[166.11].L sp|P54136|SYRC_HUMAN 1 1469.7542 -1 63591 22495 3 1469.754734 490.9254 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.59 3992.5 - 705495 - - - 0.3395 - 1.865 0.379 - 112 1 2 0 0.0005 13 0 0 0 0.00E+00 0.00E+00 - - - 4.4552 0.9985 230117_WJC_METTL3_WT_vs_EV_F07.22498.22498.2 0.000232 24-Nov R.GNTAAYLLYAFTR[166.11].L sp|P54136|SYRC_HUMAN 1 1469.7542 -1 63593 22498 2 1469.751061 735.8844 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.59 3992.8 - 576724 - - - -2.1595 - 2.352 0.429 - 257.2 1 2 0 -0.0032 13 0 0 0 0.00E+00 0.00E+00 - - - 4.4037 1 230117_WJC_METTL3_WT_vs_EV_F07.22499.22499.2 2.09E-10 16/26 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 8.3 63594 22499 2 1537.770829 769.8922 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3992.9 - 1.52E+07 - - - 0.6718 - 3.459 0.691 - 759.3 1 2 0 0.001 14 0 0 0 6.36E+07 7.67E+06 - - - 7.2586 1 230117_WJC_METTL3_WT_vs_EV_F07.22502.22502.2 3.74E-09 14/22 K.FFDDPMLLELAK.Q "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1437.7214 1.79 63597 22502 2 1437.723692 719.868 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.03 3993 - 3.01E+06 - - - 1.6018 - 2.761 0.589 - 361.2 1 2 0 0.0023 12 0 0 0 6.91E+06 3.86E+06 - - - 6.0628 1 230117_WJC_METTL3_WT_vs_EV_F07.22503.22503.3 1.50E-06 17/56 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 1.94 63598 22503 3 1519.910786 507.6435 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3993.1 - 2.64E+06 - - - 1.4297 - 2.909 0.593 - 377.1 1 2 0 0.0022 15 0 0 0 1.13E+07 5.82E+06 - - - 7.9371 1 230117_WJC_METTL3_WT_vs_EV_F07.22504.22504.3 3.61E-06 16/52 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 -1 63599 22504 3 1537.771434 513.5972 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3993.1 - 2.35E+06 - - - 1.0652 - 3.325 0.592 - 461.2 1 2 0 0.0016 14 0 0 0 0.00E+00 0.00E+00 - - - 8.3327 1 230117_WJC_METTL3_WT_vs_EV_F07.22507.22507.2 8.37E-08 22-Nov K.NTPFLYDLVMTH.A "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|E9PIC4|E9PIC4_HUMAN,tr|E9PNS2|E9PNS2_HUMAN,tr|E9PNS6|E9PNS6_HUMAN,tr|C9JAJ9|C9JAJ9_HUMAN,tr|E9PC52|E9PC52_HUMAN" 7 1449.6962 - 63602 22507 2 1449.696869 725.8554 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.08 3993.3 - 1.68E+06 - - - 0.436 - 2.343 0.596 - 404.1 1 1 0 0.0006 12 0 0 0 - - - - - 5.6831 1 230117_WJC_METTL3_WT_vs_EV_F07.22508.22508.2 1.67E-08 19/28 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 2.01 63603 22508 2 1519.910514 760.9616 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3993.4 - 1.62E+06 - - - 1.2507 - 3.137 0.608 - 1448.1 1 2 0 0.0019 15 0 0 0 6.91E+06 3.44E+06 - - - 6.3419 1 230117_WJC_METTL3_WT_vs_EV_F07.22509.22509.2 0.0039 28-Nov R.ATSFLLALEPELEAR.L "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1658.8879 -1 63604 22509 2 1658.884687 830.4512 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.25 3993.5 - 1.50E+06 - - - -1.9591 - 2.563 0.491 - 369.7 1 2 0 -0.0032 15 0 0 0 0.00E+00 0.00E+00 - - - 4.9804 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22510.22510.3 0.000325 14/56 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 1.94 63605 22510 3 1529.91925 510.9796 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3993.5 - 1.31E+06 - - - 1.5471 - 2.481 0.487 - 215.7 1 2 0 0.0024 15 0 0 0 1.13E+07 5.82E+06 - - - 6.3399 1 230117_WJC_METTL3_WT_vs_EV_F07.22511.22511.2 4.41E-07 14/28 R.ATSFLLALEPELEAR[166.11].L "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1668.8962 -1 63606 22511 2 1668.898815 835.4554 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.25 3993.7 - 1.26E+06 - - - 1.5627 - 2.969 0.513 - 705.7 1 2 0 0.0026 15 0 0 0 0.00E+00 0.00E+00 - - - 5.5047 1 230117_WJC_METTL3_WT_vs_EV_F07.22519.22519.2 0.591 20-Nov K.IADFGFGNFFK.S sp|Q9H0K1|SIK2_HUMAN 1 1261.6132 -1 63613 22519 2 1261.615975 631.8139 Serine\threonine-protein kinase SIK2 OS=Homo sapiens OX=9606 GN=SIK2 PE=1 SV=1 5.84 3994.5 - 754506 - - - 2.2321 - 2.445 0.454 - 421.2 1 2 0 0.0028 11 0 0 0 0.00E+00 0.00E+00 - - - 4.812 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.22520.22520.2 0.0319 16-Aug K.LLLPWLEAR.L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1109.6597 5.71 63614 22520 2 1109.661341 555.8371 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6 3994.5 - 1.29E+07 - - - 1.4644 - 1.681 0.26 - 266.1 1 2 0 0.0016 9 0 0 0 2.13E+08 3.73E+07 - - - 2.4635 1 230117_WJC_METTL3_WT_vs_EV_F07.22522.22522.2 6.04E-08 18-Oct R.C[160.03]WAGSLWLFK.D sp|Q9BQA1|MEP50_HUMAN 1 1266.6219 -1 63616 22522 2 1266.624849 634.3183 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 3994.6 - 5.55E+06 - - - 2.2888 - 2.239 0.597 - 275.9 1 2 0 0.0029 10 0 0 0 0.00E+00 0.00E+00 - - - 5.6994 1 230117_WJC_METTL3_WT_vs_EV_F07.22523.22523.3 9.12E-08 15/44 K.FFEVILIDPFHK[136.11].A "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 4 1511.8268 -1 63617 22523 3 1511.829692 504.9495 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 5.32 3994.7 - 3.89E+06 - - - 1.9209 - 2.464 0.549 - 243.4 1 2 0 0.0029 12 0 0 0 0.00E+00 0.00E+00 - - - 7.1596 0.9999 230117_WJC_METTL3_WT_vs_EV_F07.22524.22524.3 0.000472 15/44 K.FFEVILIDPFHK.A "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 4 1503.8126 0.88 63618 22524 3 1503.816278 502.2781 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 5.32 3994.7 - 2.78E+06 - - - 2.4538 - 2.427 0.477 - 211.4 1 2 0 0.0037 12 0 0 0 6.52E+06 7.39E+06 - - - 6.3147 0.9181 230117_WJC_METTL3_WT_vs_EV_F07.22526.22526.2 0.00141 18-Jul H.STPLWLLLSR.L sp|O94906|PRP6_HUMAN 1 1184.6917 2.86 63620 22526 2 1184.694677 593.3531 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 9.47 3994.9 - 1.63E+06 - - - 2.4757 - 1.501 0.328 - 170.8 1 1 0 0.0029 10 0 0 0 3.75E+06 1.31E+06 - - - 2.5963 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.22527.22527.2 0.0437 18-Oct R.GFGFVDFLTK[136.11].Q "sp|Q9Y4C8|RBM19_HUMAN,tr|H0YIL2|H0YIL2_HUMAN" 2 1137.595 -1 63621 22527 2 1137.598284 569.8048 Probable RNA-binding protein 19 OS=Homo sapiens OX=9606 GN=RBM19 PE=1 SV=3 5.84 3995 - 1.34E+06 - - - 2.8894 - 2.116 0.381 - 288.8 1 2 0 0.0033 10 0 0 0 0.00E+00 0.00E+00 - - - 3.9462 1 230117_WJC_METTL3_WT_vs_EV_F07.22528.22528.2 6.17E-07 19/28 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 -1 63622 22528 2 1529.920053 765.9657 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3995.1 - 1.26E+06 - - - 2.072 - 3.056 0.602 - 1088.9 1 2 0 0.0032 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2328 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22529.22529.2 5.25E-05 22-Oct K.AYVVLGQFLVLK[136.11].K sp|O75531|BAF_HUMAN 1 1356.8261 -1 63623 22529 2 1356.82866 679.4203 Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1 8.63 3995.2 - 1.13E+06 - - - 1.917 - 1.791 0.445 - 263.1 1 2 0 0.0026 12 0 0 0 0.00E+00 0.00E+00 - - - 3.8603 1 230117_WJC_METTL3_WT_vs_EV_F07.22531.22531.2 5.86E-07 14/26 K.YVVLSYLGLLSQEK.L "sp|Q9BXK5|B2L13_HUMAN,tr|F6VJB4|F6VJB4_HUMAN,tr|A0A0A0MR90|A0A0A0MR90_HUMAN,tr|F2Z2C3|F2Z2C3_HUMAN,tr|E9PDD6|E9PDD6_HUMAN,tr|A0A087WW80|A0A087WW80_HUMAN" 6 1610.892 -1 63625 22531 2 1610.895817 806.4533 Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13 PE=1 SV=1 6 3995.4 - 1.00E+06 - - - 2.3943 - 2.844 0.554 - 537.4 1 2 0 0.0039 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7545 0.9991 230117_WJC_METTL3_WT_vs_EV_F07.22532.22532.2 0.347 18-Oct R.GFGFVDFLTK.Q "sp|Q9Y4C8|RBM19_HUMAN,tr|H0YIL2|H0YIL2_HUMAN" 2 1129.5808 -1 63626 22532 2 1129.581834 565.7977 Probable RNA-binding protein 19 OS=Homo sapiens OX=9606 GN=RBM19 PE=1 SV=3 5.84 3995.6 - 970224 - - - 0.918 - 1.693 0.272 - 253.8 1 2 0 0.001 10 0 0 0 0.00E+00 0.00E+00 - - - 2.5193 1 230117_WJC_METTL3_WT_vs_EV_F07.22539.22539.2 7.26E-09 18-Dec R.C[160.03]WAGSLWLFK[136.11].D sp|Q9BQA1|MEP50_HUMAN 1 1274.6362 0.47 63632 22539 2 1274.638752 638.3254 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 3996.4 - 1.91E+07 - - - 2.0414 - 2.337 0.623 - 475 1 2 0 0.0026 10 0 0 0 1.96E+07 4.20E+07 - - - 6.0111 1 230117_WJC_METTL3_WT_vs_EV_F07.22541.22541.2 1.93E-08 17/30 K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 -1 63634 22541 2 1701.890245 851.9512 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3996.6 - 4.22E+06 - - - 1.3908 - 3.196 0.634 - 747.2 1 2 0 0.0024 16 0 0 0 0.00E+00 0.00E+00 - - - 6.5796 1 230117_WJC_METTL3_WT_vs_EV_F07.22543.22543.2 3.45E-06 16/30 K.AAGVNVEPFWPGLFAK[136.11].A sp|P05386|RLA1_HUMAN 1 1709.9021 -1 63636 22543 2 1709.904902 855.9583 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3996.7 - 2.77E+06 - - - 1.6516 - 3.209 0.581 - 663.5 1 2 0 0.0028 16 0 0 0 0.00E+00 0.00E+00 - - - 6.1979 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22544.22544.2 0.0121 16-Sep K.AFLLESLLK.N sp|Q96JM3|CHAP1_HUMAN 1 1032.6219 3.51 63637 22544 2 1032.623654 517.3182 Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2 6.05 3996.8 - 2.44E+06 - - - 1.6666 - 1.987 0.432 - 261.8 1 2 0 0.0017 9 0 0 0 6.22E+06 1.77E+06 - - - 4.2177 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.22545.22545.2 0.00502 18-Nov R.AALLELWELR[166.11].R "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1222.6949 -1 63638 22545 2 1222.697756 612.3547 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 3996.8 - 2.29E+06 - - - 2.3121 - 2.524 0.348 - 390.7 1 2 0 0.0028 10 0 0 0 0.00E+00 0.00E+00 - - - 4.1948 1 230117_WJC_METTL3_WT_vs_EV_F07.22549.22549.2 9.33E-05 15/24 R.DLYEDELVPLFEK[136.11].A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1616.8065 -1 63642 22549 2 1616.810781 809.4105 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3997.2 - 1.06E+06 - - - 2.6441 - 2.532 0.564 - 621.9 1 2 0 0.0043 13 0 0 0 0.00E+00 0.00E+00 - - - 5.5897 1 230117_WJC_METTL3_WT_vs_EV_F07.22551.22551.2 8.34E-11 15/24 R.DLYEDELVPLFEK.A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1608.7923 -1 63644 22551 2 1608.78953 805.4034 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3997.4 - 965997 - - - -1.7255 - 2.738 0.661 - 610.2 1 2 0 -0.0028 13 0 0 0 0.00E+00 0.00E+00 - - - 6.5074 1 230117_WJC_METTL3_WT_vs_EV_F07.22553.22553.3 9.73E-05 26/64 R.LGLAAAAAAAAAELYGR.A sp|Q96T25|ZIC5_HUMAN 1 1558.8467 -1 63646 22553 3 1558.850632 520.6229 Zinc finger protein ZIC 5 OS=Homo sapiens OX=9606 GN=ZIC5 PE=1 SV=2 6 3997.5 - 922972 - - - 2.4961 - 4.404 0.535 - 1311.7 1 2 0 0.0039 17 0 0 0 0.00E+00 0.00E+00 - - - 8.2489 0.9972 230117_WJC_METTL3_WT_vs_EV_F07.22556.22556.2 0.432 20-Aug R.IPLLLTSLSFK[136.11].V "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1238.773 -1 63649 22556 2 1238.775606 620.3938 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.75 3997.9 - 708769 - - - 2.1352 - 1.421 0.214 - 113.4 1 2 0 0.0026 11 0 0 0 0.00E+00 0.00E+00 - - - 1.5713 0.8598 230117_WJC_METTL3_WT_vs_EV_F07.22562.22562.2 0.0672 26-Jul F.AQPPAPTPTSAPNK[136.11].G "sp|Q99856|ARI3A_HUMAN,tr|K7EJ04|K7EJ04_HUMAN" 2 1383.7238 0 63654 22562 2 1383.725414 692.8692 AT-rich interactive domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ARID3A PE=1 SV=2 8.8 3998.5 - 1.57E+07 - - - 1.1816 - 1.248 0.285 - 72.5 1 1 0 0.0016 14 0 0 0 7.37E+05 2.36E+08 - - - 1.7014 1 230117_WJC_METTL3_WT_vs_EV_F07.22563.22563.3 0.00049 22/56 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 8.09 63655 22563 3 1581.912147 528.3103 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 3998.6 - 1.31E+07 - - - 1.9849 - 3.936 0.551 - 901.3 1 2 0 0.0031 15 0 0 0 2.04E+07 2.52E+06 - - - 8.2575 1 230117_WJC_METTL3_WT_vs_EV_F07.22564.22564.2 1.41E-05 14/26 R.APIASIHSFELDLL.- sp|Q13015|AF1Q_HUMAN 1 1524.8188 - 63656 22564 2 1524.821337 763.4167 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 4.35 3998.6 - 7.11E+06 - - - 1.6671 - 2.653 0.509 - 655.9 1 2 0 0.0025 14 0 0 0 - - - - - 5.2481 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22565.22565.2 0.0422 13/24 R.DILVEADSLWVVK[136.11].M sp|Q15208|STK38_HUMAN 1 1493.8221 -1 63657 22565 2 1493.824446 747.9183 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.03 3998.7 - 4.47E+06 - - - 1.5731 - 2.747 0.36 - 500.4 1 2 0 0.0024 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2927 1 230117_WJC_METTL3_WT_vs_EV_F07.22566.22566.3 6.22E-08 21/64 R.LGLAAAAAAAAAELYGR[166.11].A sp|Q96T25|ZIC5_HUMAN 1 1568.855 -1 63658 22566 3 1568.857199 523.9589 Zinc finger protein ZIC 5 OS=Homo sapiens OX=9606 GN=ZIC5 PE=1 SV=2 6 3998.7 - 2.62E+06 - - - 1.3946 - 3.457 0.492 - 703.3 1 2 0 0.0022 17 0 0 0 0.00E+00 0.00E+00 - - - 7.1583 1 230117_WJC_METTL3_WT_vs_EV_F07.22567.22567.2 5.32E-08 14/28 R.ELIQTSALNFLTPLR.N "sp|Q9Y371|SHLB1_HUMAN,tr|A0A087WW40|A0A087WW40_HUMAN" 2 1714.9618 -1 63659 22567 2 1714.968885 858.4882 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 6.1 3998.8 - 2.37E+06 - - - 4.1482 - 2.928 0.575 - 758.2 1 2 0 0.0071 15 0 0 0 0.00E+00 0.00E+00 - - - 5.927 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22568.22568.3 0.00881 Dec-48 R.DLYEDELVPLFEK.A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1608.7923 -1 63660 22568 3 1608.796252 537.2714 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3998.8 - 1.93E+06 - - - 2.4528 - 2.168 0.34 - 246 1 2 0 0.0039 13 0 0 0 0.00E+00 0.00E+00 - - - 4.4276 1 230117_WJC_METTL3_WT_vs_EV_F07.22570.22570.2 7.03E-08 14/26 R.DYLHLPPEIVPATL.H "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1576.8501 - 63662 22570 2 1576.853321 789.4323 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.35 3999 - 1.77E+06 - - - 2.0459 - 2.602 0.537 - 627.2 1 1 0 0.0032 14 0 0 0 - - - - - 5.406 1 230117_WJC_METTL3_WT_vs_EV_F07.22572.22572.2 0.000739 19/32 R.LGLAAAAAAAAAELYGR.A sp|Q96T25|ZIC5_HUMAN 1 1558.8467 -1 63664 22572 2 1558.85043 780.4306 Zinc finger protein ZIC 5 OS=Homo sapiens OX=9606 GN=ZIC5 PE=1 SV=2 6 3999.2 - 1.66E+06 - - - 2.3665 - 3.482 0.497 - 892.1 1 2 0 0.0037 17 0 0 0 0.00E+00 0.00E+00 - - - 5.778 0.9997 230117_WJC_METTL3_WT_vs_EV_F07.22573.22573.2 1.01E-06 15/32 R.LVSDIIDPVALEIPLSK.N "sp|Q5UIP0|RIF1_HUMAN,tr|H7C2B5|H7C2B5_HUMAN" 2 1821.0499 -1 63665 22573 2 1821.051544 911.5322 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 4.03 3999.3 - 1.29E+06 - - - 0.8934 - 2.672 0.363 - 488.7 1 2 0 0.0016 17 0 0 0 0.00E+00 0.00E+00 - - - 4.1379 1 230117_WJC_METTL3_WT_vs_EV_F07.22577.22577.2 0.000478 15/20 K.GIVLLEELLPK.G sp|Q9Y3D6|FIS1_HUMAN 1 1222.7537 -1 63669 22577 2 1222.756628 612.3841 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 4.53 3999.7 - 1.13E+06 - - - 2.4142 - 2.534 0.466 - 833 1 2 0 0.003 11 0 0 0 0.00E+00 0.00E+00 - - - 4.9973 1 230117_WJC_METTL3_WT_vs_EV_F07.22606.22606.2 5.36E-08 28-Dec K.FDVILLEPPLEEYYR.E "sp|Q9HCE5|MET14_HUMAN,tr|D6RBL4|D6RBL4_HUMAN" 2 1894.9717 -1 63688 22606 2 1894.975213 948.4931 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4 4001.6 - 0 - - - 1.8713 - 2.411 0.587 - 327.5 1 2 0 0.0035 15 0 0 0 0.00E+00 0.00E+00 - - - 5.5391 0.9971 230117_WJC_METTL3_WT_vs_EV_F07.22607.22607.2 0.011 May-32 R.WVGGPEIELIAIATGGR.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1737.9414 -1 63689 22607 2 1737.939625 869.978 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 4001.7 - 0 - - - -1.0041 - 1.123 0.406 - 22.9 1 2 0 -0.0017 17 0 0 0 0.00E+00 0.00E+00 - - - 2.3244 0.8746 230117_WJC_METTL3_WT_vs_EV_F07.22623.22623.3 7.62 Jul-56 R.GVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1555.9008 -1 63704 22623 3 1555.903439 519.6409 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 4003.8 - 206888 - - - 1.7276 - 1.222 0.095 - 28.3 3 2 0 0.0027 15 0 0 0 0.00E+00 0.00E+00 - - - -0.0993 0.9996 230117_WJC_METTL3_WT_vs_EV_F07.23293.23293.2 0.000125 30-May K.LGFAGLVQEISFGTTK.D "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1666.893 -1 63739 23293 2 1666.894172 834.4538 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 4130.3 - 2.02E+06 - - - 0.6893 - 1.229 0.596 - 46.7 1 2 0 0.0011 16 0 0 0 0.00E+00 0.00E+00 - - - 3.9496 0.9889 230117_WJC_METTL3_WT_vs_EV_F07.23294.23294.2 2.74 28-Apr R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 -1 63740 23294 2 1581.910718 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4130.4 - 1.84E+06 - - - 1.0816 - 0.925 0.211 - 45.8 1 2 0 0.0017 15 0 0 0 0.00E+00 0.00E+00 - - - 0.4072 0.9956 230117_WJC_METTL3_WT_vs_EV_F07.23303.23303.2 0.0984 20-Sep K.GIVLLEELLPK.G sp|Q9Y3D6|FIS1_HUMAN 1 1222.7537 -1 63747 23303 2 1222.756464 612.3841 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 4.53 4131.5 - 786373 - - - 2.2801 - 1.473 0.157 - 105.6 1 2 0 0.0028 11 0 0 0 0.00E+00 0.00E+00 - - - 1.2475 0.9992 230117_WJC_METTL3_WT_vs_EV_F07.23304.23304.2 0.00736 26-Jul R.LLVPTQFVGAIIGK.E "sp|O00425|IF2B3_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 3 1454.8861 -1 63748 23304 2 1454.887619 728.4503 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 4131.7 - 765874 - - - 1.053 - 1.558 0.332 - 103.8 1 2 0 0.0015 14 0 0 0 0.00E+00 0.00E+00 - - - 2.6054 0.9994 230117_WJC_METTL3_WT_vs_EV_F07.23553.23553.2 0.0772 16-Oct R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.5 63770 23553 2 1108.65616 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4179.9 - 401426 - - - 2.6401 - 2 0.355 - 253.1 1 2 0 0.0029 9 0 0 0 1.55E+07 1.04E+07 - - - 3.6674 0.9995 230117_WJC_METTL3_WT_vs_EV_F07.23554.23554.2 6.63E-05 26-Aug K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.53 63771 23554 2 1618.970516 810.4902 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4180 - 65727.2 - - - 2.9167 - 1.919 0.478 - 124.3 1 2 0 0.0047 14 0 0 0 2.61E+06 1.70E+06 - - - 4.2057 0.9369 230117_WJC_METTL3_WT_vs_EV_F07.23575.23575.2 0.612 22-Apr R.SFLLDLLNATGK.D "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1290.7184 0.63 63781 23575 2 1290.723752 646.3665 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.55 4183.1 - 0 - - - 4.1829 - 0.907 0.182 - 38.8 1 2 0 0.0054 12 0 0 0 8.14E+05 1.30E+06 - - - 0.1267 1 230117_WJC_METTL3_WT_vs_EV_F07.23578.23578.2 7.12E-07 24-Sep K.SLEEIYLFSLPIK.E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN,tr|H3BNG3|H3BNG3_HUMAN,tr|H0YE27|H0YE27_HUMAN" 7 1550.8596 0.5 63784 23578 2 1550.865501 776.4371 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.53 4183.5 - 0 - - - 3.8069 - 1.84 0.615 - 238.7 1 2 0 0.0059 13 0 0 0 5.45E+05 1.09E+06 - - - 5.1465 0.8814 230117_WJC_METTL3_WT_vs_EV_F07.23665.23665.2 0.711 28-Mar R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 47.55 63794 23665 2 1581.914442 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 4199.6 - 26474.3 - - - 3.4357 - 0.707 0.178 - 22.4 2 2 0 0.0054 15 0 0 0 5.99E+05 1.26E+04 - - - -0.6329 0.9328 230117_WJC_METTL3_WT_vs_EV_F08.06675.06675.2 3.29 12-Apr R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 1870.03 63845 6675 2 776.379705 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1995.3 - 136084 - - - -2.5735 - 1.165 0.15 - 48.9 2 2 0 -0.002 7 0 0 0 1.27E+07 6.79E+03 - - - 0.4977 0.9783 230117_WJC_METTL3_WT_vs_EV_F08.07662.07662.3 1.23 Mar-60 K.ATAGDTHLGGEDFDNR.L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1674.7234 49.16 63866 7662 3 1674.722438 559.2484 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2178 - 14452.4 - - - -0.569 - 0.803 0.309 - 11.8 1 2 0 -0.001 16 0 0 0 1.12E+06 2.28E+04 - - - 1.4218 0.9074 230117_WJC_METTL3_WT_vs_EV_F08.09368.09368.2 0.0957 22-Feb R.AQVQEFC[160.03]DYGTK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1444.6293 1.84 63918 9368 2 1444.624533 723.3219 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2495.5 - 16898.7 - - - -3.286 - 0.472 0.474 - 13.3 1 2 0 -0.0047 12 0 0 0 2.76E+06 1.50E+06 - - - 0.5651 0.9985 230117_WJC_METTL3_WT_vs_EV_F08.09380.09380.2 0.00754 22-Mar R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 1.84 63919 9380 2 1452.643027 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2497.6 - 13658.4 - - - -0.3118 - 0.97 0.488 - 24 1 2 0 -0.0005 12 0 0 0 2.76E+06 1.50E+06 - - - 2.5651 0.9161 230117_WJC_METTL3_WT_vs_EV_F08.10011.10011.2 0.289 14-May T.DNLELSLR.S "sp|Q9Y2X7|GIT1_HUMAN,tr|A0A0C4DGN6|A0A0C4DGN6_HUMAN,tr|J3QRU8|J3QRU8_HUMAN" 3 958.5084 213.88 63938 10011 2 958.508537 480.2615 ARF GTPase-activating protein GIT1 OS=Homo sapiens OX=9606 GN=GIT1 PE=1 SV=2 4.37 2613.8 - 54997.3 - - - 0.1847 - 1.223 0.393 - 154.9 1 1 0 0.0002 8 0 0 0 2.77E+06 1.30E+04 - - - 2.5508 0.9998 230117_WJC_METTL3_WT_vs_EV_F08.10774.10774.3 1.20E-05 Jul-68 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 2.53 63987 10774 3 2070.862675 691.296 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2750.4 - 25790.6 - - - -1.7466 - 1.596 0.635 - 45.2 1 2 0 -0.0036 18 0 0 0 2.99E+06 1.18E+06 - - - 6.7827 0.9924 230117_WJC_METTL3_WT_vs_EV_F08.11120.11120.3 0.0033 May-96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 2.5 64017 11120 3 2559.234639 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2810.7 - 121240 - - - -2.5844 - 1.343 0.348 - 22 1 2 0 -0.0066 25 0 0 0 1.29E+06 5.15E+05 - - - 3.0965 0.9689 230117_WJC_METTL3_WT_vs_EV_F08.11121.11121.3 0.00132 Mar-96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 2.5 64018 11121 3 2569.238045 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2810.8 - 97534.9 - - - -4.4675 - 0.855 0.423 - 5.9 1 2 0 -0.0115 25 0 0 0 1.29E+06 5.15E+05 - - - 2.8924 0.9938 230117_WJC_METTL3_WT_vs_EV_F08.11152.11152.2 0.463 12-May K.YLYEIAR.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 926.4862 1280.89 64019 11152 2 926.486361 464.2504 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6 2816.3 - 58622.2 - - - 0.2083 - 1.074 0.238 - 93.3 1 2 0 0.0002 7 0 0 0 7.99E+06 6.24E+03 - - - 1.025 0.9922 230117_WJC_METTL3_WT_vs_EV_F08.11393.11393.4 0.0121 7/108 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 1.7 64034 11393 4 2080.015884 521.0129 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2859.7 - 60010.4 - - - -3.1966 - 1.222 0.399 - 18.8 1 2 0 -0.0066 19 0 0 0 8.43E+06 4.95E+06 - - - 2.7649 0.8644 230117_WJC_METTL3_WT_vs_EV_F08.11401.11401.4 0.000988 7/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 1.7 64035 11401 4 2089.030982 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2861 - 139666 - - - 476.1645 - 1.694 0.49 - 46.4 1 2 0 0.9942 19 0 0 0 8.41E+06 4.95E+06 - - - 3.3939 0.944 230117_WJC_METTL3_WT_vs_EV_F08.12411.12411.2 1.49 16-May R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 999 64125 12411 2 1030.590504 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 3035.8 - 47716 - - - -0.5075 - 0.927 0.127 - 71.2 1 2 0 -0.0005 9 0 0 0 3.22E+06 0.00E+00 - - - -0.2404 0.997 230117_WJC_METTL3_WT_vs_EV_F08.12468.12468.3 0.00502 May-52 R.SDSFENPVLQQHFR[166.11].N "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1712.8146 0.86 64137 12468 3 1712.810612 571.9455 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.3 3045.1 - 63777.7 - - - -2.3301 - 1.052 0.456 - 31.1 1 2 0 -0.004 14 0 0 0 9.53E+05 1.11E+06 - - - 3.7576 0.9979 230117_WJC_METTL3_WT_vs_EV_F08.12474.12474.3 0.00338 Jul-68 R.VAPEEHPVLLTEAPLNPK.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1953.0571 11.07 64138 12474 3 1953.053206 652.0263 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 3046 - 61261.1 - - - -2.0081 - 1.448 0.396 - 54.4 1 2 0 -0.0039 18 0 0 0 4.14E+06 3.74E+05 - - - 3.8757 0.9351 230117_WJC_METTL3_WT_vs_EV_F08.12804.12804.3 0.106 5/128 R.SDSPVPTAPTSGGPKPSTASAVPELATDPELEK.K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3232.5987 5.94 64183 12804 3 3232.592911 1078.5402 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3102 - 42260.9 - - - -1.7902 - 1.034 0.231 - 14.9 1 2 0 -0.0058 33 0 0 0 7.46E+06 1.25E+06 - - - 1.1907 0.9833 230117_WJC_METTL3_WT_vs_EV_F08.12982.12982.2 0.0146 16-May R.VLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 11 1028.5866 999 64212 12982 2 1028.583543 515.3006 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3131.8 - 40314.1 - - - -2.9818 - 1.131 0.329 - 87.5 1 2 0 -0.0031 9 0 0 0 2.58E+06 0.00E+00 - - - 1.8262 0.9023 230117_WJC_METTL3_WT_vs_EV_F08.13090.13090.2 5.17 12-May R.AVTIFIR.G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 818.5014 7.18 64229 13090 2 818.499499 410.258 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3150 - 17238.8 - - - -2.3519 - 1.039 0.131 - 125.9 1 2 0 -0.0019 7 0 0 0 4.94E+06 6.88E+05 - - - 0.1292 0.9955 230117_WJC_METTL3_WT_vs_EV_F08.13308.13308.2 0.00403 16-Jun R.AFGYYGPLR[166.11].S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1052.5319 1.06 64270 13308 2 1052.529386 527.2732 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3184.3 - 23076.9 - - - -2.3752 - 1.16 0.452 - 152.2 1 2 0 -0.0025 9 0 0 0 9.34E+06 8.79E+06 - - - 2.8081 0.9956 230117_WJC_METTL3_WT_vs_EV_F08.13315.13315.2 0.000647 16-May R.AFGYYGPLR.S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1042.5236 1.06 64272 13315 2 1042.521607 522.2691 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3185.3 - 56227 - - - -1.9271 - 1.176 0.405 - 110.1 1 2 0 -0.002 9 0 0 0 9.33E+06 8.77E+06 - - - 2.5007 0.9411 230117_WJC_METTL3_WT_vs_EV_F08.13488.13488.2 1.25 18-Apr K.SYLYPSTLVR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1207.6476 0.3 64303 13488 2 1207.644429 604.8311 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 3213.6 - 27510.9 - - - -2.6622 - 0.966 0.229 - 75.5 1 2 0 -0.0032 10 0 0 0 7.94E+05 2.62E+06 - - - 0.6348 0.9778 230117_WJC_METTL3_WT_vs_EV_F08.13678.13678.2 0.465 14-Apr K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 1.74 64340 13678 2 895.480632 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3245.1 - 66556.7 - - - 0.3104 - 0.819 0.223 - 42.8 1 2 0 0.0003 8 0 0 0 6.68E+06 3.84E+06 - - - 0.0858 0.9871 230117_WJC_METTL3_WT_vs_EV_F08.13751.13751.2 0.00169 14-Jul K.NLYIISVK.G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 948.5644 1.35 64356 13751 2 948.562159 475.2895 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3257.1 - 351871 - - - -2.3815 - 1.201 0.289 - 210.4 1 2 0 -0.0023 8 0 0 0 6.41E+06 4.74E+06 - - - 1.7272 0.9583 230117_WJC_METTL3_WT_vs_EV_F08.13765.13765.3 0.149 Apr-64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 167.11 64358 13765 3 1786.980468 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3259.6 - 58448.7 - - - -1.361 - 1.065 0.247 - 14 2 2 0 -0.0024 17 0 0 0 7.56E+06 4.52E+04 - - - 1.3129 0.9853 230117_WJC_METTL3_WT_vs_EV_F08.13858.13858.2 0.0864 16-Jul R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 0.76 64374 13858 2 952.593828 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3275 - 289531 - - - -1.9841 - 1.317 0.211 - 157.8 1 2 0 -0.0019 9 0 0 0 1.58E+07 2.07E+07 - - - 1.3955 0.9956 230117_WJC_METTL3_WT_vs_EV_F08.13917.13917.2 0.22 16-Jul R.TEIIILATR.T "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 10 1028.623 2.58 64388 13917 2 1028.620373 515.3188 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.66 3284.5 - 129661 - - - -2.55 - 1.66 0.333 - 212.5 1 2 0 -0.0026 9 0 0 0 3.19E+06 1.24E+06 - - - 2.966 0.9066 230117_WJC_METTL3_WT_vs_EV_F08.13956.13956.2 1.43 18-Apr K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 17 64394 13956 2 1149.578447 575.7982 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3291.1 - 29737.6 - - - -2.968 - 0.732 0.305 - 42.9 1 2 0 -0.0034 10 0 0 0 3.42E+06 2.01E+05 - - - 0.4218 1 230117_WJC_METTL3_WT_vs_EV_F08.14068.14068.2 1.57E-05 18-Nov K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 2.72 64418 14068 2 1154.640032 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3309 - 137241 - - - -2.289 - 2.02 0.55 - 324.4 1 2 0 -0.0026 10 0 0 0 3.26E+07 1.20E+07 - - - 5.065 0.9966 230117_WJC_METTL3_WT_vs_EV_F08.14345.14345.2 0.155 14-Jul R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 71.1 64466 14345 2 1000.557694 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3354.9 - 167662 - - - -1.6381 - 1.828 0.231 - 148.6 1 2 0 -0.0016 8 0 0 0 1.03E+07 1.45E+05 - - - 2.5659 1 230117_WJC_METTL3_WT_vs_EV_F08.14361.14361.4 0.000203 9/126 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 2.54 64471 14361 4 2682.065926 671.5247 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3357.1 - 62722.7 - - - -1.4608 - 1.921 0.625 - 63.1 1 2 0 -0.0039 22 0 0 0 1.93E+06 7.61E+05 - - - 4.8785 0.9991 230117_WJC_METTL3_WT_vs_EV_F08.14539.14539.2 0.0479 14-Sep R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 35.1 64504 14539 2 1000.558541 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3385.2 - 226559 - - - -0.7916 - 2.138 0.313 - 300.8 1 2 0 -0.0008 8 0 0 0 2.32E+07 6.60E+05 - - - 3.6443 0.9828 230117_WJC_METTL3_WT_vs_EV_F08.14630.14630.2 0.498 14-Jul K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 0.86 64519 14630 2 998.57679 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3400.3 - 138391 - - - -2.0489 - 1.313 0.195 - 224.2 1 2 0 -0.002 8 0 0 0 1.38E+07 1.61E+07 - - - 1.3019 0.9659 230117_WJC_METTL3_WT_vs_EV_F08.14636.14636.2 0.508 16-Jun R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 18.82 64520 14636 2 1006.567019 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3401.3 - 44601.3 - - - -2.8602 - 1.124 0.24 - 87.6 1 2 0 -0.0029 9 0 0 0 4.86E+06 2.58E+05 - - - 1.1509 0.9128 230117_WJC_METTL3_WT_vs_EV_F08.14726.14726.2 0.114 16-Apr R.FAVGIVIGR.N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 930.5651 1.63 64544 14726 2 930.562221 466.2898 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3414.5 - 15558.4 - - - -3.0798 - 0.976 0.21 - 60.3 1 2 0 -0.0029 9 0 0 0 1.39E+06 8.53E+05 - - - 0.5209 0.9956 230117_WJC_METTL3_WT_vs_EV_F08.14835.14835.2 0.0051 14-Jul R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 8.01 64579 14835 2 1000.556468 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3431 - 68648.5 - - - -2.8634 - 1.593 0.375 - 164.5 1 2 0 -0.0029 8 0 0 0 7.13E+06 8.90E+05 - - - 3.2141 0.9948 230117_WJC_METTL3_WT_vs_EV_F08.14840.14840.2 0.0608 16-Jun R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 1249.29 64580 14840 2 1006.567824 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3431.8 - 100947 - - - -2.0605 - 1.225 0.377 - 82 1 2 0 -0.0021 9 0 0 0 1.71E+07 1.37E+04 - - - 2.412 0.9776 230117_WJC_METTL3_WT_vs_EV_F08.14892.14892.2 3.18 26-Mar R.GVVDSEDIPLNLSR.E "sp|Q12931|TRAP1_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 6 1512.7784 385.83 64590 14892 2 1512.779369 757.3965 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.03 3440 - 130512 - - - 0.6491 - 0.842 0.188 - 25.7 1 2 0 0.001 14 0 0 0 4.28E+06 1.11E+04 - - - -0.0023 0.9457 230117_WJC_METTL3_WT_vs_EV_F08.14986.14986.2 1.26 16-Mar R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 0.98 64617 14986 2 989.591161 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3454.2 - 32185.8 - - - 0.196 - 0.648 0.236 - 21.4 1 2 0 0.0002 9 0 0 0 1.19E+07 1.21E+07 - - - -0.4712 0.9969 230117_WJC_METTL3_WT_vs_EV_F08.15035.15035.2 0.00828 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 64.11 64627 15035 2 1006.566607 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3462 - 1.79E+07 - - - -3.2695 - 1.95 0.459 - 255.3 1 2 0 -0.0033 9 0 0 0 7.93E+08 1.24E+07 - - - 4.3622 0.9951 230117_WJC_METTL3_WT_vs_EV_F08.15057.15057.2 0.00655 16-Nov K.IAFAITAIK.G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 946.5852 1.23 64632 15057 2 946.58129 474.2999 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3465.4 - 169011 - - - -4.082 - 2.399 0.394 - 332.5 1 2 0 -0.0039 9 0 0 0 1.22E+07 9.90E+06 - - - 4.4814 0.9747 230117_WJC_METTL3_WT_vs_EV_F08.15103.15103.2 1.5 12-Apr K.ELEFYLR.K "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 968.4967 0.82 64640 15103 2 968.499056 485.2556 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.53 3472.7 - 16320.8 - - - 2.3986 - 1.035 0.118 - 97.9 1 2 0 0.0023 7 0 0 0 1.58E+06 1.93E+06 - - - 0.0208 0.8477 230117_WJC_METTL3_WT_vs_EV_F08.15108.15108.2 0.0983 18-Mar K.LGDDIDLIVR.C sp|O15371|EIF3D_HUMAN 1 1127.6186 1.36 64642 15108 2 1127.613741 564.8166 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3473.4 - 30021.9 - - - -4.3437 - 0.714 0.343 - 25.6 1 2 0 -0.0049 10 0 0 0 1.09E+06 8.02E+05 - - - 0.6325 0.991 230117_WJC_METTL3_WT_vs_EV_F08.15117.15117.2 0.561 12-May K.ELEFYLR[166.11].K "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 978.505 0.82 64645 15117 2 978.505174 490.2598 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.53 3474.8 - 55478 - - - 0.1748 - 0.976 0.243 - 129.3 1 2 0 0.0002 7 0 0 0 1.58E+06 1.92E+06 - - - 0.7588 0.9966 230117_WJC_METTL3_WT_vs_EV_F08.15230.15230.2 0.00258 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 1887.79 64673 15230 2 1006.566419 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3492.6 - 275634 - - - -3.4563 - 1.907 0.478 - 249.6 1 2 0 -0.0035 9 0 0 0 3.37E+07 1.79E+04 - - - 4.438 0.9864 230117_WJC_METTL3_WT_vs_EV_F08.15243.15243.2 0.00264 20-May R.IVLLDSSLEYK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1278.7071 9.62 64679 15243 2 1278.702204 640.3608 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3494.5 - 28133.6 - - - -3.8437 - 1.335 0.372 - 62.8 1 2 0 -0.0049 11 0 0 0 1.22E+07 1.27E+06 - - - 2.5687 1 230117_WJC_METTL3_WT_vs_EV_F08.15303.15303.2 9.81E-07 18-Sep R.EC[160.03]LNLWGYER.V sp|Q86U44|MTA70_HUMAN 1 1338.6027 2.66 64699 15303 2 1338.59774 670.3086 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3503.4 - 31682 - - - -3.6837 - 2.006 0.6 - 476.5 1 2 0 -0.0049 10 0 0 0 1.69E+07 6.35E+06 - - - 5.4142 0.9984 230117_WJC_METTL3_WT_vs_EV_F08.15304.15304.2 0.00697 18-Jun R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 2.66 64700 15304 2 1348.608049 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3503.6 - 14326.5 - - - -2.1444 - 1.453 0.564 - 158.4 1 2 0 -0.0029 10 0 0 0 1.69E+07 6.35E+06 - - - 4.2487 0.9998 230117_WJC_METTL3_WT_vs_EV_F08.15323.15323.3 2.63E-08 Aug-76 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 2.53 64706 15323 3 2187.03258 730.0199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3506.5 - 61036.9 - - - -2.417 - 1.872 0.638 - 65.8 1 2 0 -0.0053 20 0 0 0 1.29E+07 5.13E+06 - - - 7.1727 0.9842 230117_WJC_METTL3_WT_vs_EV_F08.15328.15328.3 4.70E-07 Oct-76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 2.53 64708 15328 3 2198.04336 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3507.1 - 106661 - - - 453.8931 - 2.356 0.607 - 114.7 1 2 0 0.9972 20 0 0 0 1.29E+07 5.13E+06 - - - 7.1102 1 230117_WJC_METTL3_WT_vs_EV_F08.15330.15330.2 3.55E-09 Sep-38 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 4.17 64710 15330 2 2187.031296 1094.5262 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3507.4 - 63352.7 - - - -3.0041 - 2.439 0.647 - 225.1 1 2 0 -0.0066 20 0 0 0 5.24E+06 1.26E+06 - - - 6.0097 0.999 230117_WJC_METTL3_WT_vs_EV_F08.15437.15437.2 0.00076 22-Jun K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 8.82 64743 15437 2 1332.740275 667.3774 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3524.1 - 39534.5 - - - 0.093 - 1.47 0.374 - 106.6 1 2 0 0.0001 12 0 0 0 2.21E+07 2.50E+06 - - - 2.817 0.9964 230117_WJC_METTL3_WT_vs_EV_F08.15591.15591.2 0.361 22-Jun R.FLAVGLVDNTVR.L sp|Q15393|SF3B3_HUMAN 1 1302.7296 1.21 64784 15591 2 1302.728473 652.3721 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3548.4 - 8271.75 - - - -0.8544 - 1.376 0.287 - 136.6 1 2 0 -0.0011 12 0 0 0 5.16E+05 4.27E+05 - - - 2.0003 0.9782 230117_WJC_METTL3_WT_vs_EV_F08.15601.15601.2 0.442 14-May R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 2.79 64788 15601 2 1000.557134 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3549.9 - 66236.2 - - - -2.1978 - 1.197 0.217 - 78 1 2 0 -0.0022 8 0 0 0 3.52E+06 1.26E+06 - - - 1.1854 0.9948 230117_WJC_METTL3_WT_vs_EV_F08.15637.15637.2 0.0495 16-Sep R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 999 64799 15637 2 1006.56653 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3555.5 - 135588 - - - -3.346 - 1.713 0.382 - 203.7 1 2 0 -0.0034 9 0 0 0 5.30E+06 0.00E+00 - - - 3.4186 0.9972 230117_WJC_METTL3_WT_vs_EV_F08.15659.15659.2 0.00027 18-Jul R.YLYTLVITDK.E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1227.6751 1.54 64810 15659 2 1227.672957 614.8448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3558.5 - 48760.1 - - - -1.7382 - 1.616 0.34 - 118.3 1 2 0 -0.0021 10 0 0 0 1.02E+07 6.62E+06 - - - 2.8913 0.8794 230117_WJC_METTL3_WT_vs_EV_F08.15660.15660.2 0.149 18-Apr R.YLYTLVITDK[136.11].E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1235.6893 1.54 64811 15660 2 1235.683811 618.8519 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3558.6 - 34670 - - - -4.4348 - 0.991 0.251 - 35.3 1 2 0 -0.0055 10 0 0 0 1.02E+07 6.62E+06 - - - 0.8679 0.9987 230117_WJC_METTL3_WT_vs_EV_F08.15682.15682.2 0.0159 16-Jul K.GIFLGDQWR.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1090.556 2.91 64823 15682 2 1090.555236 546.2853 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3561.7 - 85217 - - - -0.6813 - 1.497 0.374 - 169.9 1 2 0 -0.0007 9 0 0 0 1.67E+06 5.73E+05 - - - 2.9704 0.9994 230117_WJC_METTL3_WT_vs_EV_F08.15687.15687.2 1.76E-05 26-Jun K.FYGPEGPYGVFAGR.D sp|O00264|PGRC1_HUMAN 1 1515.7147 1.61 64826 15687 2 1515.714056 758.8646 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3562.4 - 27658.5 - - - -0.4011 - 1.45 0.564 - 102.1 1 2 0 -0.0006 14 0 0 0 2.95E+06 1.84E+06 - - - 4.1389 0.8773 230117_WJC_METTL3_WT_vs_EV_F08.15699.15699.2 0.000168 26-May K.FYGPEGPYGVFAGR[166.11].D sp|O00264|PGRC1_HUMAN 1 1525.7229 1.61 64831 15699 2 1525.712081 763.8687 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3564.1 - 44079.4 - - - -7.1133 - 1.252 0.355 - 79 1 2 0 -0.0109 14 0 0 0 2.95E+06 1.84E+06 - - - 2.2236 0.9866 230117_WJC_METTL3_WT_vs_EV_F08.15776.15776.2 0.129 16-Mar K.LLQDFFNGR.D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1108.5665 9.03 64855 15776 2 1108.566234 555.2905 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3575.9 - 15390.1 - - - -0.2787 - 0.745 0.333 - 32.9 1 2 0 -0.0003 9 0 0 0 7.24E+06 8.02E+05 - - - 0.6488 1 230117_WJC_METTL3_WT_vs_EV_F08.15809.15809.2 2.28E-07 30-Aug K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 999 64864 15809 2 1789.884335 895.9496 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3580.7 - 0 - - - -0.1721 - 1.97 0.631 - 182.4 1 2 0 -0.0003 16 0 0 0 3.80E+06 0.00E+00 - - - 5.3684 0.9989 230117_WJC_METTL3_WT_vs_EV_F08.15852.15852.2 0.00915 20-May R.LYEAYLPETFR.R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1400.6976 3.13 64879 15852 2 1400.696797 701.3561 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3587.1 - 42868.1 - - - -0.5854 - 1.337 0.458 - 80.6 1 2 0 -0.0008 11 0 0 0 2.23E+06 7.12E+05 - - - 3.2092 0.9442 230117_WJC_METTL3_WT_vs_EV_F08.15870.15870.2 1.33 16-May R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 999 64883 15870 2 1006.568299 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3589.9 - 93124.2 - - - -1.5886 - 0.889 0.204 - 61.7 1 2 0 -0.0016 9 0 0 0 3.66E+06 0.00E+00 - - - 0.2069 0.9927 230117_WJC_METTL3_WT_vs_EV_F08.15872.15872.2 0.804 20-Apr R.LYEAYLPETFR[166.11].R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1410.7059 3.1 64884 15872 2 1410.708902 706.3602 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3590.1 - 32308.2 - - - 2.1372 - 0.91 0.273 - 60.1 1 2 0 0.003 11 0 0 0 2.21E+06 7.12E+05 - - - 0.8013 0.9051 230117_WJC_METTL3_WT_vs_EV_F08.15902.15902.2 3.85 26-Mar K.NIYVLQELDNPGAK.R "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1572.8148 1.2 64896 15902 2 1572.811824 787.4147 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3594.6 - 0 - - - -1.8743 - 0.671 0.259 - 32.2 1 2 0 -0.0029 14 0 0 0 7.54E+05 6.28E+05 - - - -0.0482 0.9739 230117_WJC_METTL3_WT_vs_EV_F08.15910.15910.2 1.72 20-Jun K.LVFLGLDNAGK.T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1145.6445 1.61 64900 15910 2 1145.642016 573.8295 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3595.7 - 37325.6 - - - -2.1324 - 1.423 0.156 - 96.5 2 2 0 -0.0024 11 0 0 0 2.11E+06 1.31E+06 - - - 1.0123 0.9856 230117_WJC_METTL3_WT_vs_EV_F08.15924.15924.2 0.0659 20-May K.LVFLGLDNAGK[136.11].T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1153.6587 1.61 64906 15924 2 1153.655458 577.8366 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3597.6 - 24032.1 - - - -2.7747 - 1.122 0.338 - 59.7 1 2 0 -0.0032 11 0 0 0 2.11E+06 1.31E+06 - - - 1.8479 0.9995 230117_WJC_METTL3_WT_vs_EV_F08.15970.15970.2 0.0191 18-Jul R.FEELC[160.03]SDLFR.S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1314.5914 5.03 64918 15970 2 1314.593022 658.303 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.14 3604.6 - 16691.7 - - - 1.2049 - 1.563 0.38 - 209 1 2 0 0.0016 10 0 0 0 7.18E+05 1.43E+05 - - - 3.0938 0.9814 230117_WJC_METTL3_WT_vs_EV_F08.16015.16015.2 0.358 18-May R.ILVATNLFGR[166.11].G "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 6 1112.6581 1.43 64930 16015 2 1112.656388 557.3364 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 9.75 3611.4 - 24400.2 - - - -1.5827 - 1.139 0.217 - 73.9 1 2 0 -0.0018 10 0 0 0 1.65E+06 1.15E+06 - - - 1.0065 0.9978 230117_WJC_METTL3_WT_vs_EV_F08.16038.16038.2 0.0043 16-Jun R.YLTVAAVFR[166.11].G "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 5 1048.5945 3.48 64940 16038 2 1048.593722 525.3045 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3614.6 - 28356 - - - -0.7286 - 1.321 0.349 - 123.6 1 2 0 -0.0008 9 0 0 0 6.90E+06 1.98E+06 - - - 2.4239 0.9985 230117_WJC_METTL3_WT_vs_EV_F08.16044.16044.2 0.00885 20-Jun K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 0.93 64942 16044 2 1197.719753 599.8679 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3615.5 - 46215.5 - - - -1.2582 - 1.381 0.461 - 149.9 1 2 0 -0.0015 11 0 0 0 3.12E+06 3.35E+06 - - - 3.3187 0.9812 230117_WJC_METTL3_WT_vs_EV_F08.16051.16051.2 0.00611 20-Apr K.VANVSLLALYK.G sp|P62266|RS23_HUMAN 1 1189.7071 0.93 64946 16051 2 1189.705437 595.8608 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3616.5 - 44026.9 - - - -1.3642 - 1.08 0.223 - 60.7 1 2 0 -0.0016 11 0 0 0 3.12E+06 3.35E+06 - - - 0.8958 0.9984 230117_WJC_METTL3_WT_vs_EV_F08.16067.16067.2 9.30E-05 18-Jun R.FEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1252.6088 9.96 64953 16067 2 1252.606019 627.3117 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3618.7 - 66703.5 - - - -2.2218 - 1.552 0.568 - 111.9 1 2 0 -0.0028 10 0 0 0 9.94E+06 9.98E+05 - - - 4.4623 0.9129 230117_WJC_METTL3_WT_vs_EV_F08.16088.16088.2 0.183 14-Apr R.DFVNYLVR.L sp|Q08211|DHX9_HUMAN 1 1024.5342 0.87 64957 16088 2 1024.531658 513.2744 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.84 3622.1 - 42381.7 - - - -2.4626 - 0.855 0.229 - 73.5 1 2 0 -0.0025 8 0 0 0 1.82E+06 2.10E+06 - - - 0.2591 0.9965 230117_WJC_METTL3_WT_vs_EV_F08.16150.16150.2 0.0111 16-Jul K.GFGFVSFER[166.11].H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1054.5112 0.94 64978 16150 2 1054.508817 528.2629 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3631.7 - 29291.2 - - - -2.2133 - 1.407 0.401 - 199.3 1 2 0 -0.0023 9 0 0 0 1.12E+07 1.19E+07 - - - 2.9899 0.9773 230117_WJC_METTL3_WT_vs_EV_F08.16158.16158.2 0.0123 16-May K.GFGFVSFER.H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1044.5029 0.93 64981 16158 2 1044.500904 523.2587 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3632.8 - 60216 - - - -1.8928 - 1.125 0.22 - 102.1 1 2 0 -0.002 9 0 0 0 1.14E+07 1.23E+07 - - - 1.0061 0.9706 230117_WJC_METTL3_WT_vs_EV_F08.16168.16168.2 0.0373 20-Apr M.PPYTVVYFPVR.G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1336.718 1.29 64984 16168 2 1336.715638 669.3663 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3634.3 - 18817 - - - -1.7363 - 0.855 0.287 - 55.5 1 2 0 -0.0023 11 0 0 0 1.32E+06 1.02E+06 - - - 0.7363 0.9901 230117_WJC_METTL3_WT_vs_EV_F08.16172.16172.2 0.0124 20-Apr M.PPYTVVYFPVR[166.11].G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1346.7262 1.29 64986 16172 2 1346.723762 674.3704 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3634.9 - 17153.5 - - - -1.8318 - 0.994 0.356 - 52.9 1 2 0 -0.0025 11 0 0 0 1.32E+06 1.02E+06 - - - 1.6534 0.9988 230117_WJC_METTL3_WT_vs_EV_F08.16185.16185.2 0.000328 20-Jun K.MALDIEIATYR.K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1294.6591 1.68 64988 16185 2 1294.657625 648.3368 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3636.9 - 19098.3 - - - -1.1571 - 1.42 0.491 - 147 1 2 0 -0.0015 11 0 0 0 1.25E+06 7.44E+05 - - - 3.6157 0.9146 230117_WJC_METTL3_WT_vs_EV_F08.16212.16212.2 0.707 16-Apr R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 198.87 64994 16212 2 1006.567023 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3641.2 - 47054.4 - - - -2.8562 - 0.794 0.28 - 40 1 2 0 -0.0029 9 0 0 0 6.67E+06 3.36E+04 - - - 0.4408 0.9991 230117_WJC_METTL3_WT_vs_EV_F08.16216.16216.2 0.00133 18-Apr R.LFDQAFGLPR[166.11].L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1172.6218 1.17 64995 16216 2 1172.621667 587.3182 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3641.8 - 30171.2 - - - -0.0827 - 1.302 0.433 - 54 1 2 0 -0.0001 10 0 0 0 6.49E+06 5.54E+06 - - - 2.9757 0.998 230117_WJC_METTL3_WT_vs_EV_F08.16221.16221.2 0.00189 18-May R.LFDQAFGLPR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1162.6135 1.17 64998 16221 2 1162.612505 582.314 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3642.5 - 27188.2 - - - -0.8507 - 1.233 0.405 - 91.4 1 2 0 -0.001 10 0 0 0 6.48E+06 5.53E+06 - - - 2.6167 0.9964 230117_WJC_METTL3_WT_vs_EV_F08.16252.16252.2 0.00541 Apr-32 R.AAVEEGIVLGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1683.8978 2.01 65007 16252 2 1683.894373 842.9562 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3647.2 - 21997.8 - - - -2.0298 - 1.195 0.45 - 34 1 2 0 -0.0034 17 0 0 0 9.68E+05 4.83E+05 - - - 2.8016 0.9968 230117_WJC_METTL3_WT_vs_EV_F08.16256.16256.2 0.00515 16-May K.MC[160.03]LFAGFQR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1128.5209 0.88 65009 16256 2 1128.520376 565.2677 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3647.6 - 28532.3 - - - -0.4253 - 1.122 0.338 - 124.8 1 2 0 -0.0005 9 0 0 0 1.03E+06 1.17E+06 - - - 1.8703 0.9947 230117_WJC_METTL3_WT_vs_EV_F08.16301.16301.2 0.0862 18-Apr R.LWIANYSLPR.A sp|O43172|PRP4_HUMAN 1 1231.6713 3.58 65027 16301 2 1231.670214 616.8429 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3654.1 - 77141.6 - - - -0.9166 - 0.976 0.369 - 81.9 1 2 0 -0.0011 10 0 0 0 2.09E+06 5.85E+05 - - - 1.6983 0.9983 230117_WJC_METTL3_WT_vs_EV_F08.16310.16310.2 0.00389 16-Apr R.QINWTVLYR[166.11].R "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1201.6483 0.89 65032 16310 2 1201.647475 601.8314 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 8.75 3655.3 - 41225.7 - - - -0.6974 - 0.991 0.499 - 64 1 2 0 -0.0008 9 0 0 0 1.27E+06 1.43E+06 - - - 2.7002 0.9962 230117_WJC_METTL3_WT_vs_EV_F08.16314.16314.3 0.00887 Jun-44 K.KPGGFDISLFYR.D "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1398.7296 1.92 65036 16314 3 1398.727213 467.2505 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.59 3655.9 - 19938 - - - -1.6965 - 1.291 0.354 - 72.8 1 2 0 -0.0024 12 0 0 0 6.25E+05 3.25E+05 - - - 3.1941 0.9914 230117_WJC_METTL3_WT_vs_EV_F08.16340.16340.2 0.355 22-Mar R.DIISIAEDEDLR.V "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1387.6831 3.63 65048 16340 2 1387.683916 694.8488 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 3.77 3659.6 - 51293.8 - - - 0.5952 - 0.831 0.286 - 34.5 1 2 0 0.0008 12 0 0 0 3.22E+05 8.87E+04 - - - 0.666 0.948 230117_WJC_METTL3_WT_vs_EV_F08.16362.16362.2 0.147 22-Apr K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 999 65059 16362 2 1252.746649 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3662.9 - 46285.6 - - - -2.9319 - 0.952 0.263 - 53.4 1 2 0 -0.0037 12 0 0 0 2.41E+06 0.00E+00 - - - 0.8529 0.998 230117_WJC_METTL3_WT_vs_EV_F08.16366.16366.2 0.00364 24-Jun R.IITLTGPTNAIFK.A sp|Q15365|PCBP1_HUMAN 1 1387.8075 4.77 65060 16366 2 1387.804821 694.911 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3663.5 - 41268.1 - - - -1.9318 - 1.432 0.487 - 93.2 1 2 0 -0.0027 13 0 0 0 1.57E+06 3.28E+05 - - - 3.5587 0.9988 230117_WJC_METTL3_WT_vs_EV_F08.16370.16370.2 3.29E-05 20-Jul R.FFDEESYSLLR.K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1404.6561 1.75 65062 16370 2 1404.654549 703.3353 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3664.1 - 115461 - - - -1.1369 - 1.47 0.476 - 94.5 1 2 0 -0.0016 11 0 0 0 3.56E+06 2.04E+06 - - - 3.5985 0.9993 230117_WJC_METTL3_WT_vs_EV_F08.16372.16372.2 0.00038 20-May R.FFDEESYSLLR[166.11].K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1414.6644 1.75 65063 16372 2 1414.664778 708.3395 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3664.3 - 56278.3 - - - 0.2559 - 1.052 0.53 - 49.5 1 2 0 0.0004 11 0 0 0 3.56E+06 2.04E+06 - - - 3.0926 0.9772 230117_WJC_METTL3_WT_vs_EV_F08.16577.16577.3 0.0981 Apr-96 R.AETSDVANAVLDGADC[160.03]IMLSGETAK.G sp|P30613|KPYR_HUMAN 1 2537.1625 999 65132 16577 3 2537.167558 846.7281 Pyruvate kinase PKLR OS=Homo sapiens OX=9606 GN=PKLR PE=1 SV=2 3.77 3695.5 - 18492.3 - - - 1.9802 - 0.953 0.23 - 12.7 1 2 0 0.005 25 0 0 0 8.37E+05 0.00E+00 - - - 0.9921 0.9963 230117_WJC_METTL3_WT_vs_EV_F08.16578.16578.2 0.0233 22-Jun K.DAGVIAGLNVLR.L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1196.6877 3.06 65133 16578 2 1196.686752 599.3511 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3695.7 - 0 - - - -0.8097 - 1.358 0.284 - 141 1 2 0 -0.001 12 0 0 0 6.90E+05 2.25E+05 - - - 1.9435 1 230117_WJC_METTL3_WT_vs_EV_F08.16593.16593.2 3.19E-06 26-Sep K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.54 65141 16593 2 1762.788521 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3697.7 - 70911.3 - - - -3.7321 - 1.991 0.602 - 262.6 1 2 0 -0.0066 14 0 0 0 2.23E+06 1.45E+06 - - - 5.2134 1 230117_WJC_METTL3_WT_vs_EV_F08.16596.16596.2 2.71E-06 26-Aug K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.54 65142 16596 2 1772.801006 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3698.1 - 24830.4 - - - -1.3335 - 1.913 0.583 - 172.9 1 2 0 -0.0024 14 0 0 0 2.23E+06 1.45E+06 - - - 4.9741 0.9971 230117_WJC_METTL3_WT_vs_EV_F08.16646.16646.2 9.87E-05 18-Jul R.LGLEDFESLK[136.11].V sp|Q15208|STK38_HUMAN 1 1157.606 0.6 65169 16646 2 1157.602595 579.8103 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3705 - 41658.8 - - - -2.9025 - 1.552 0.505 - 112.7 1 2 0 -0.0034 10 0 0 0 1.77E+06 2.98E+06 - - - 3.9968 0.9978 230117_WJC_METTL3_WT_vs_EV_F08.16650.16650.2 0.00224 18-Jun R.LGLEDFESLK.V sp|Q15208|STK38_HUMAN 1 1149.5918 0.6 65171 16650 2 1149.589139 575.8032 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3705.5 - 18420.8 - - - -2.2756 - 1.614 0.46 - 72.2 1 2 0 -0.0026 10 0 0 0 1.77E+06 2.98E+06 - - - 3.774 0.9997 230117_WJC_METTL3_WT_vs_EV_F08.16670.16670.2 3.63E-05 24-Jul K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 0.18 65180 16670 2 1600.744788 801.3794 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3708.2 - 11500.8 - - - 0.2986 - 1.636 0.555 - 161.8 1 2 0 0.0005 13 0 0 0 5.70E+05 3.24E+06 - - - 4.4035 0.8603 230117_WJC_METTL3_WT_vs_EV_F08.16678.16678.2 8.69 12-Apr K.NFGIWLR.Y "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 904.4919 0.84 65182 16678 2 904.490629 453.2532 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 9.75 3709.6 - 63195 - - - -1.4295 - 1.081 0.028 - 83.6 1 2 0 -0.0013 7 0 0 0 4.42E+06 5.24E+06 - - - -0.5058 0.9935 230117_WJC_METTL3_WT_vs_EV_F08.16708.16708.2 0.0724 22-May R.IYGLGSLALYEK[136.11].A sp|P36542|ATPG_HUMAN 1 1333.7373 1.58 65191 16708 2 1333.739244 667.8759 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6 3714.2 - 29798.9 - - - 1.4546 - 1.122 0.195 - 52.3 1 2 0 0.0019 12 0 0 0 4.88E+06 3.09E+06 - - - 0.7835 0.9898 230117_WJC_METTL3_WT_vs_EV_F08.16715.16715.2 0.106 14-Mar K.IPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1059.5502 1.28 65193 16715 2 1059.552603 530.7824 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3715.2 - 32497.7 - - - 2.301 - 0.745 0.333 - 41.6 1 2 0 0.0024 8 0 0 0 1.10E+08 8.56E+07 - - - 0.612 0.9958 230117_WJC_METTL3_WT_vs_EV_F08.16724.16724.2 0.00526 14-Jul K.IPDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1069.5584 1.28 65196 16724 2 1069.556712 535.7865 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3716.6 - 113118 - - - -1.6109 - 1.257 0.353 - 179.5 1 2 0 -0.0017 8 0 0 0 1.09E+08 8.53E+07 - - - 2.3375 0.8613 230117_WJC_METTL3_WT_vs_EV_F08.16749.16749.2 1.28 18-Apr K.ELLGQGLLLR.S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1110.6761 0.89 65204 16749 2 1110.674143 556.3453 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3720.2 - 15750.3 - - - -1.7566 - 0.831 0.15 - 47.2 1 2 0 -0.002 10 0 0 0 4.12E+05 4.61E+05 - - - -0.3685 0.9929 230117_WJC_METTL3_WT_vs_EV_F08.16807.16807.2 0.000614 26-Jun K.FYGPAGPYGIFAGR.D sp|O15173|PGRC2_HUMAN 1 1471.7248 1.51 65220 16807 2 1471.719485 736.8697 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3729.3 - 43939.5 - - - -3.6352 - 1.333 0.469 - 117.8 1 2 0 -0.0053 14 0 0 0 3.64E+06 2.41E+06 - - - 3.2247 0.9994 230117_WJC_METTL3_WT_vs_EV_F08.16808.16808.2 0.000118 26-Jun K.FYGPAGPYGIFAGR[166.11].D sp|O15173|PGRC2_HUMAN 1 1481.7331 1.51 65221 16808 2 1481.732334 741.8738 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3729.4 - 38803.4 - - - -0.5203 - 1.335 0.599 - 100.3 1 2 0 -0.0008 14 0 0 0 3.64E+06 2.41E+06 - - - 4.19 0.9986 230117_WJC_METTL3_WT_vs_EV_F08.16839.16839.2 0.00187 16-May K.YDWDLLAAR.S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1121.5506 1.77 65231 16839 2 1121.549309 561.7826 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3734.2 - 84359 - - - -1.1145 - 1.414 0.433 - 87.5 1 2 0 -0.0013 9 0 0 0 1.44E+06 8.12E+05 - - - 3.241 0.9996 230117_WJC_METTL3_WT_vs_EV_F08.16840.16840.2 0.00011 16-Jun K.YDWDLLAAR[166.11].S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1131.5588 1.74 65232 16840 2 1131.559197 566.7867 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3734.3 - 47520.8 - - - 0.3252 - 1.464 0.491 - 134.9 1 2 0 0.0004 9 0 0 0 1.41E+06 8.12E+05 - - - 3.7702 1 230117_WJC_METTL3_WT_vs_EV_F08.16841.16841.2 0.000454 20-Oct K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 12.68 65233 16841 2 1184.710753 593.3637 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3734.4 - 343906 - - - -1.7895 - 2.017 0.529 - 398.7 1 2 0 -0.0021 11 0 0 0 9.74E+06 7.68E+05 - - - 4.8456 0.9805 230117_WJC_METTL3_WT_vs_EV_F08.16852.16852.2 0.0605 14-Apr R.DWVLNEFK.H "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1049.5182 0.03 65237 16852 2 1049.514911 525.7664 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3736.1 - 11647.7 - - - -3.13 - 0.944 0.393 - 64.2 1 2 0 -0.0033 8 0 0 0 9.62E+05 2.83E+07 - - - 1.7689 0.993 230117_WJC_METTL3_WT_vs_EV_F08.16869.16869.2 0.00891 18-Jun R.DAVLLVFANK.Q "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 5 1088.623 2.02 65242 16869 2 1088.619985 545.3188 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 5.84 3738.7 - 12105.5 - - - -2.7659 - 1.357 0.363 - 110.2 1 2 0 -0.003 10 0 0 0 1.54E+06 7.63E+05 - - - 2.5733 0.9989 230117_WJC_METTL3_WT_vs_EV_F08.16878.16878.2 0.000807 20-Jun K.TVLELQYVLDK[136.11].L "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1327.7479 1.12 65245 16878 2 1327.747402 664.8812 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.37 3740 - 51654.4 - - - -0.3517 - 1.329 0.421 - 61.7 1 2 0 -0.0005 11 0 0 0 3.23E+06 2.89E+06 - - - 2.9198 0.995 230117_WJC_METTL3_WT_vs_EV_F08.16893.16893.2 0.0587 18-Apr K.GIGFLTSGWR.F sp|Q8IXM3|RM41_HUMAN 1 1092.5716 1.12 65250 16893 2 1092.572975 547.2931 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 9.75 3742.3 - 31125.8 - - - 1.232 - 1.112 0.221 - 38.5 1 2 0 0.0013 10 0 0 0 8.94E+05 7.99E+05 - - - 0.9692 0.8927 230117_WJC_METTL3_WT_vs_EV_F08.16897.16897.2 1.4 20-Mar R.VFSWGFGGYGR.L sp|Q9P258|RCC2_HUMAN 1 1231.5774 1.64 65252 16897 2 1231.576413 616.796 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 8.72 3742.8 - 17710.5 - - - -0.8363 - 0.637 0.22 - 29.9 1 2 0 -0.001 11 0 0 0 1.66E+06 1.01E+06 - - - -0.5544 1 230117_WJC_METTL3_WT_vs_EV_F08.16906.16906.3 8.55E-08 18/76 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 1.94 65256 16906 3 2197.082924 733.3694 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3744 - 60888.6 - - - -1.5166 - 3.658 0.602 - 379.6 1 2 0 -0.0033 20 0 0 0 1.16E+07 5.96E+06 - - - 8.3971 1 230117_WJC_METTL3_WT_vs_EV_F08.16924.16924.2 2.56E-11 Sep-38 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 -1 65258 16924 2 2197.078643 1099.5504 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3747 - 0 - - - -3.465 - 2.596 0.726 - 137.8 1 2 0 -0.0076 20 0 0 0 0.00E+00 0.00E+00 - - - 6.7462 0.9503 230117_WJC_METTL3_WT_vs_EV_F08.16934.16934.2 1.24 30-Jul R.ALIAGGGAPEIELALR[166.11].L sp|P50991|TCPD_HUMAN 1 1559.8911 10.41 65263 16934 2 1559.887184 780.9528 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3748.3 - 17984.4 - - - -2.4861 - 1.147 0.177 - 151.3 1 2 0 -0.0039 16 0 0 0 8.25E+06 7.93E+05 - - - 0.6843 0.9986 230117_WJC_METTL3_WT_vs_EV_F08.16953.16953.2 0.000175 18-Aug R.VFYYLVQDLK[136.11].C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1294.7053 1.6 65270 16953 2 1294.70291 648.3599 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3751.3 - 92808.5 - - - -1.8267 - 1.728 0.481 - 248.2 1 2 0 -0.0024 10 0 0 0 2.85E+06 1.78E+06 - - - 4.1197 0.9988 230117_WJC_METTL3_WT_vs_EV_F08.16954.16954.2 0.00285 18-Aug R.YVEFNLLYDR[166.11].G "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1340.664 1.28 65271 16954 2 1340.662134 671.3393 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.37 3751.4 - 57625 - - - -1.4083 - 1.789 0.439 - 194 1 2 0 -0.0019 10 0 0 0 9.18E+05 7.19E+05 - - - 3.9064 0.9971 230117_WJC_METTL3_WT_vs_EV_F08.16963.16963.2 7.62E-05 18-Aug R.VFYYLVQDLK.C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1286.6911 1.61 65275 16963 2 1286.687849 644.3528 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3752.6 - 49034.4 - - - -2.5072 - 1.671 0.413 - 228.1 1 2 0 -0.0032 10 0 0 0 2.87E+06 1.78E+06 - - - 3.5235 0.9685 230117_WJC_METTL3_WT_vs_EV_F08.16973.16973.2 0.0659 16-Mar R.GFFGFPGPR[166.11].S "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN" 2 990.4951 2.42 65280 16973 2 990.49355 496.2548 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.75 3754 - 37218.4 - - - -1.5719 - 0.632 0.392 - 29 1 2 0 -0.0016 9 0 0 0 2.19E+06 9.04E+05 - - - 0.6083 0.9899 230117_WJC_METTL3_WT_vs_EV_F08.17050.17050.2 0.0965 18-Apr R.FC[160.03]IWTESAFR[166.11].K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1325.6102 0.75 65308 17050 2 1325.607214 663.8124 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3765.7 - 127118 - - - -2.2624 - 1.256 0.316 - 68.4 2 2 0 -0.003 10 0 0 0 9.09E+05 1.22E+06 - - - 1.8758 0.992 230117_WJC_METTL3_WT_vs_EV_F08.17083.17083.2 0.000123 24-Jul K.ILTFDQLALDSPK[136.11].G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1467.8064 0.87 65322 17083 2 1467.799638 734.9105 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3770.5 - 71343.2 - - - -4.6382 - 1.717 0.501 - 148.4 1 2 0 -0.0068 13 0 0 0 1.74E+06 1.99E+06 - - - 4.1267 0.9678 230117_WJC_METTL3_WT_vs_EV_F08.17136.17136.2 0.211 14-Apr R.GFC[160.03]FITFK.E "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1018.4946 1.01 65345 17136 2 1018.492701 510.2546 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.22 3778.2 - 29505.4 - - - -1.8881 - 0.88 0.282 - 60.2 1 2 0 -0.0019 8 0 0 0 5.17E+06 5.10E+06 - - - 0.7377 0.9978 230117_WJC_METTL3_WT_vs_EV_F08.17167.17167.2 0.00228 Apr-36 R.YEGILYTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2100.0627 1.18 65354 17167 2 2100.06149 1051.0386 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3783.1 - 16080 - - - -0.5605 - 1.078 0.419 - 41.5 1 2 0 -0.0012 19 0 0 0 4.93E+05 4.20E+05 - - - 2.32 0.9978 230117_WJC_METTL3_WT_vs_EV_F08.17213.17213.2 0.0126 18-Dec K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.79 65375 17213 2 1176.718133 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3789.8 - 201283 - - - -2.3727 - 2.324 0.34 - 389.5 1 2 0 -0.0028 10 0 0 0 3.53E+07 1.97E+07 - - - 3.9052 1 230117_WJC_METTL3_WT_vs_EV_F08.17217.17217.3 7.08E-10 14/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 278.92 65376 17217 3 1603.758724 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3790.4 - 755283 - - - -3.2523 - 2.473 0.636 - 263.7 1 2 0 -0.0052 12 0 0 0 7.03E+07 2.52E+05 - - - 8.139 0.9856 230117_WJC_METTL3_WT_vs_EV_F08.17219.17219.3 0.154 Jun-56 R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 2.97 65378 17219 3 1742.954238 581.9938 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3790.6 - 130584 - - - -3.0052 - 1.412 0.301 - 41.7 1 2 0 -0.0052 15 0 0 0 6.23E+05 2.10E+05 - - - 2.7947 0.9921 230117_WJC_METTL3_WT_vs_EV_F08.17225.17225.2 5.29E-05 22-Jul R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 164.03 65382 17225 2 1613.765489 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3791.4 - 153721 - - - -4.1648 - 1.617 0.443 - 120.2 1 2 0 -0.0067 12 0 0 0 2.80E+08 1.71E+06 - - - 3.5754 1 230117_WJC_METTL3_WT_vs_EV_F08.17226.17226.2 1.05E-05 18-Dec F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 65383 17226 2 1343.607803 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3791.6 - 220659 - - - -2.7233 - 2.526 0.604 - 536.1 1 1 0 -0.0037 10 0 0 0 2.34E+06 0.00E+00 - - - 6.0875 0.8585 230117_WJC_METTL3_WT_vs_EV_F08.17238.17238.2 0.0311 May-34 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 -1 65388 17238 2 1968.060452 985.0433 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3793.3 - 458557 - - - -5.8931 - 1.213 0.26 - 51 1 2 0 -0.0116 18 0 0 0 0.00E+00 0.00E+00 - - - 1.4325 0.9365 230117_WJC_METTL3_WT_vs_EV_F08.17260.17260.2 0.00044 22-Jun K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.38 65404 17260 2 1317.698439 659.862 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3796.3 - 0 - - - -8.2993 - 1.443 0.514 - 64.2 1 2 0 -0.0109 12 0 0 0 1.95E+05 5.15E+05 - - - 3.7989 0.9867 230117_WJC_METTL3_WT_vs_EV_F08.17265.17265.2 0.726 16-Aug K.EIIDLVLDR.L "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 9 1084.6128 3.84 65407 17265 2 1084.609392 543.3137 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.03 3796.9 - 583790 - - - -3.1652 - 1.606 0.236 - 268.1 1 2 0 -0.0034 9 0 0 0 3.60E+06 9.39E+05 - - - 2.1536 0.9408 230117_WJC_METTL3_WT_vs_EV_F08.17270.17270.2 0.0438 22-Jul K.TVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1309.6952 -1 65412 17270 2 1309.687428 655.8549 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3797.5 - 150660 - - - -5.9151 - 1.565 0.286 - 79.1 1 2 0 -0.0077 12 0 0 0 0.00E+00 0.00E+00 - - - 2.3294 1 230117_WJC_METTL3_WT_vs_EV_F08.17271.17271.2 0.000158 26-Aug R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 2.02 65413 17271 2 1487.769524 744.8959 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3797.7 - 148950 - - - -5.2031 - 1.943 0.529 - 168.7 1 2 0 -0.0077 14 0 0 0 2.94E+06 1.46E+06 - - - 4.6126 0.9729 230117_WJC_METTL3_WT_vs_EV_F08.17284.17284.3 0.0319 May-52 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.73 65422 17284 3 1487.771867 496.933 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3799.4 - 50932.6 - - - -3.6282 - 1.103 0.341 - 39.8 1 2 0 -0.0054 14 0 0 0 6.17E+05 3.56E+05 - - - 2.6008 1 230117_WJC_METTL3_WT_vs_EV_F08.17351.17351.2 2.10E-06 13/22 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 115.4 65447 17351 2 1603.757238 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3809.6 - 6.27E+06 - - - -4.1789 - 2.068 0.564 - 449.2 1 2 0 -0.0067 12 0 0 0 3.85E+08 3.34E+06 - - - 5.1164 0.9379 230117_WJC_METTL3_WT_vs_EV_F08.17360.17360.2 0.00129 30-Apr R.LMNETTAVALAYGIYK.Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1756.907 999 65450 17360 2 1756.897163 879.4608 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3811 - 0 - - - -5.5751 - 0.904 0.444 - 30.6 1 2 0 -0.0098 16 0 0 0 1.10E+06 0.00E+00 - - - 2.0692 0.997 230117_WJC_METTL3_WT_vs_EV_F08.17389.17389.2 0.000894 20-May K.WYLENVYPELR.V sp|Q10471|GALT2_HUMAN 1 1480.7351 0.98 65463 17389 2 1480.731697 741.3748 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3815.1 - 42075 - - - -2.2745 - 1.325 0.467 - 70.2 1 2 0 -0.0034 11 0 0 0 5.33E+06 5.42E+06 - - - 3.2505 0.9497 230117_WJC_METTL3_WT_vs_EV_F08.17400.17400.2 0.000174 28-Jun K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 2.04 65466 17400 2 1548.914152 775.4692 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3816.8 - 9995.67 - - - -6.3121 - 1.429 0.389 - 74.8 1 2 0 -0.0098 15 0 0 0 1.69E+06 8.31E+05 - - - 2.7887 0.9997 230117_WJC_METTL3_WT_vs_EV_F08.17428.17428.3 2.75E-07 Dec-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 198.58 65477 17428 3 1603.758646 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3820.8 - 162035 - - - -3.301 - 2.224 0.592 - 223.3 1 2 0 -0.0053 12 0 0 0 6.78E+07 3.42E+05 - - - 7.3543 1 230117_WJC_METTL3_WT_vs_EV_F08.17438.17438.2 4.03E-07 14/18 F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 999 65482 17438 2 1343.601211 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3822.2 - 106192 - - - -7.6294 - 2.787 0.624 - 727.2 1 1 0 -0.0103 10 0 0 0 1.99E+06 0.00E+00 - - - 6.5076 0.9809 230117_WJC_METTL3_WT_vs_EV_F08.17443.17443.2 0.00169 20-Jul K.WYLENVYPELR[166.11].V sp|Q10471|GALT2_HUMAN 1 1490.7433 0.98 65484 17443 2 1490.734422 746.3789 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3822.8 - 282241 - - - -5.9789 - 1.735 0.472 - 181.2 1 2 0 -0.0089 11 0 0 0 5.33E+06 5.42E+06 - - - 4.015 0.9805 230117_WJC_METTL3_WT_vs_EV_F08.17447.17447.2 0.00405 20-May K.FLFVDADQIVR.T sp|Q9NYU2|UGGG1_HUMAN 1 1321.703 999 65488 17447 2 1321.697182 661.8588 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.21 3823.4 - 68438.5 - - - -4.4299 - 1.372 0.362 - 73.2 1 2 0 -0.0059 11 0 0 0 9.72E+05 0.00E+00 - - - 2.5685 0.9996 230117_WJC_METTL3_WT_vs_EV_F08.17456.17456.2 0.000111 22-Jul R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 122.25 65491 17456 2 1613.77411 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3824.7 - 0 - - - 1.1774 - 1.623 0.45 - 140.3 1 2 0 0.0019 12 0 0 0 4.32E+08 3.53E+06 - - - 3.6383 0.9695 230117_WJC_METTL3_WT_vs_EV_F08.17461.17461.3 0.0432 Jul-56 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 4.16 65494 17461 3 1658.900554 553.977 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3825.4 - 157209 - - - -5.1317 - 1.48 0.33 - 69 1 2 0 -0.0085 15 0 0 0 5.25E+06 1.26E+06 - - - 3.2398 0.9883 230117_WJC_METTL3_WT_vs_EV_F08.17465.17465.2 6.90E-05 28-Nov K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 3.55 65496 17465 2 1658.899926 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3825.9 - 70055.7 - - - -5.5102 - 2.349 0.46 - 386.7 1 2 0 -0.0091 15 0 0 0 3.21E+06 9.05E+05 - - - 4.5353 0.9422 230117_WJC_METTL3_WT_vs_EV_F08.17474.17474.2 0.151 20-Apr K.ILLTQENPFFR.K sp|Q08J23|NSUN2_HUMAN 1 1376.7452 2.15 65503 17474 2 1376.737309 689.3799 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3827.1 - 82710.6 - - - -5.7578 - 1.087 0.405 - 66.5 1 2 0 -0.0079 11 0 0 0 1.12E+06 5.22E+05 - - - 2.2555 0.9976 230117_WJC_METTL3_WT_vs_EV_F08.17486.17486.2 0.00753 16-Aug R.GFAFVYFER[166.11].L sp|Q13595|TRA2A_HUMAN 1 1144.5581 0.91 65512 17486 2 1144.555308 573.2863 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3828.6 - 99246.4 - - - -2.4402 - 1.78 0.418 - 315.6 1 2 0 -0.0028 9 0 0 0 2.65E+06 2.92E+06 - - - 3.7956 1 230117_WJC_METTL3_WT_vs_EV_F08.17492.17492.2 0.000104 16-Sep R.GFAFVYFER.L sp|Q13595|TRA2A_HUMAN 1 1134.5498 0.91 65516 17492 2 1134.547563 568.2822 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3829.3 - 94250.9 - - - -1.999 - 1.98 0.529 - 439.7 1 2 0 -0.0023 9 0 0 0 2.66E+06 2.92E+06 - - - 4.9237 0.9957 230117_WJC_METTL3_WT_vs_EV_F08.17501.17501.2 0.105 26-Sep K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.42 65522 17501 2 1416.837849 709.4289 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3830.5 - 42313.2 - - - -3.7527 - 2.182 0.449 - 249 1 2 0 -0.0053 14 0 0 0 1.29E+06 9.11E+05 - - - 4.3136 1 230117_WJC_METTL3_WT_vs_EV_F08.17506.17506.2 5.87E-08 26-Oct K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.42 65525 17506 2 1408.825633 705.4218 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3831.3 - 0 - - - -2.3658 - 2.411 0.648 - 367.5 1 2 0 -0.0033 14 0 0 0 1.29E+06 9.11E+05 - - - 6.0345 1 230117_WJC_METTL3_WT_vs_EV_F08.17525.17525.2 8.02E-08 18-Nov F.PPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1343.6115 49.05 65537 17525 2 1343.599026 672.813 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3833.8 - 137548 - - - -9.2557 - 2.373 0.623 - 442.3 1 1 0 -0.0124 10 0 0 0 1.48E+06 3.02E+04 - - - 6.0507 0.8929 230117_WJC_METTL3_WT_vs_EV_F08.17526.17526.2 0.143 24-Apr K.VLGTAFDPFLGGK.N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1320.7078 20.6 65538 17526 2 1320.699301 661.3612 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3833.9 - 112443 - - - -6.4261 - 1.15 0.352 - 43.4 1 2 0 -0.0085 13 0 0 0 5.81E+06 2.82E+05 - - - 1.9969 0.9968 230117_WJC_METTL3_WT_vs_EV_F08.17534.17534.2 0.0212 20-Oct K.ELGIWEPLAVK.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1253.702 15.85 65543 17534 2 1253.69832 627.8583 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3834.9 - 79741.1 - - - -2.9146 - 1.859 0.418 - 355.3 1 2 0 -0.0037 11 0 0 0 1.16E+07 7.35E+05 - - - 3.8046 1 230117_WJC_METTL3_WT_vs_EV_F08.17568.17568.2 1.48E-06 13/22 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 158.54 65556 17568 2 1603.758641 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3839.9 - 3.97E+06 - - - -3.3041 - 2.097 0.572 - 466.8 1 2 0 -0.0053 12 0 0 0 3.04E+08 1.92E+06 - - - 5.2125 0.9889 230117_WJC_METTL3_WT_vs_EV_F08.17576.17576.2 2.05E-05 20-Sep R.QLLEEMLTSYR[166.11].L sp|O75688|PPM1B_HUMAN 1 1391.6994 0.37 65557 17576 2 1391.692854 696.857 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3841.3 - 0 - - - -4.7194 - 1.972 0.366 - 395.4 1 2 0 -0.0066 11 0 0 0 2.54E+05 6.80E+05 - - - 3.5792 1 230117_WJC_METTL3_WT_vs_EV_F08.17578.17578.2 1.17E-07 13/26 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.91 65559 17578 2 1669.884496 835.9552 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3841.6 - 0 - - - -6.8471 - 2.491 0.574 - 517.5 1 2 0 -0.0114 14 0 0 0 7.89E+06 8.71E+06 - - - 5.5673 1 230117_WJC_METTL3_WT_vs_EV_F08.17581.17581.2 3.66E-07 13/26 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.91 65562 17581 2 1661.872515 831.9481 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3842 - 0 - - - -5.5449 - 2.453 0.592 - 516.6 1 2 0 -0.0092 14 0 0 0 7.89E+06 8.71E+06 - - - 5.6624 0.9903 230117_WJC_METTL3_WT_vs_EV_F08.17583.17583.2 0.0146 22-Jun K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 1.42 65564 17583 2 1314.785878 658.4028 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3842.2 - 0 - - - -3.99 - 1.427 0.424 - 117.1 1 2 0 -0.0052 12 0 0 0 1.05E+06 7.40E+05 - - - 3.1066 0.9955 230117_WJC_METTL3_WT_vs_EV_F08.17587.17587.3 0.00274 Jun-52 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.82 65566 17587 3 1661.876276 554.9679 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3842.8 - 123273 - - - -3.2818 - 1.514 0.383 - 36.9 1 2 0 -0.0055 14 0 0 0 2.12E+06 2.57E+06 - - - 3.9108 0.9937 230117_WJC_METTL3_WT_vs_EV_F08.17588.17588.2 0.00931 24-May R.LGSTIFVANLDFK.V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1423.7711 2.29 65567 17588 2 1423.768241 712.8928 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3842.9 - 56155.7 - - - -2.02 - 1.174 0.371 - 88.6 1 2 0 -0.0029 13 0 0 0 8.57E+05 3.74E+05 - - - 2.192 0.9994 230117_WJC_METTL3_WT_vs_EV_F08.17589.17589.3 0.00729 4/120 K.ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3062.5011 -1 65568 17589 3 3062.499559 1021.841 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3843 - 52146.4 - - - -0.5097 - 1.372 0.441 - 9.5 1 2 0 -0.0016 31 0 0 0 0.00E+00 0.00E+00 - - - 4.1839 0.9974 230117_WJC_METTL3_WT_vs_EV_F08.17604.17604.3 0.00679 5/120 K.ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK.G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3054.4869 4.67 65574 17604 3 3054.480521 1019.1696 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3845.2 - 59522.4 - - - -2.095 - 1.167 0.434 - 14.8 1 2 0 -0.0064 31 0 0 0 5.67E+05 1.21E+05 - - - 3.7322 0.9846 230117_WJC_METTL3_WT_vs_EV_F08.17610.17610.2 0.0922 20-Apr K.VAVFFGGLSIK.K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1136.6594 0.96 65580 17610 2 1136.656881 569.337 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3846 - 34907.8 - - - -2.1994 - 0.986 0.334 - 56 1 2 0 -0.0025 11 0 0 0 7.14E+05 7.47E+05 - - - 1.469 0.9954 230117_WJC_METTL3_WT_vs_EV_F08.17619.17619.2 0.00915 26-Jul K.LVINGNPITIFQER.D sp|P04406|G3P_HUMAN 1 1612.8937 1.86 65583 17619 2 1612.888542 807.4541 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3847.4 - 39923.5 - - - -3.1924 - 1.548 0.453 - 127.7 1 2 0 -0.0051 14 0 0 0 1.96E+06 1.05E+06 - - - 3.4818 0.9994 230117_WJC_METTL3_WT_vs_EV_F08.17644.17644.3 6.86E-08 Dec-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 377.09 65595 17644 3 1603.757221 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3851.1 - 140356 - - - -4.1895 - 2.25 0.594 - 188.4 1 2 0 -0.0067 12 0 0 0 4.34E+07 1.15E+05 - - - 7.4084 0.9984 230117_WJC_METTL3_WT_vs_EV_F08.17695.17695.3 1.90E-06 Jul-56 R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 1.86 65610 17695 3 2001.963837 668.3319 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3859 - 20262.6 - - - -4.9431 - 1.777 0.561 - 71.3 1 2 0 -0.0099 15 0 0 0 4.34E+06 2.33E+06 - - - 6.292 0.985 230117_WJC_METTL3_WT_vs_EV_F08.17705.17705.2 0.00768 26-Apr K.AFYPEEISSMVLTK.M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1613.8011 178.08 65614 17705 2 1613.796428 807.9078 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3860.4 - 117522 - - - -2.8925 - 1.002 0.383 - 35.1 1 2 0 -0.0047 14 0 0 0 1.42E+07 7.96E+04 - - - 1.8734 0.9601 230117_WJC_METTL3_WT_vs_EV_F08.17711.17711.2 0.139 28-Mar R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 4.53 65618 17711 2 1700.892597 851.4565 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3861.3 - 0 - - - -3.4717 - 1.069 0.287 - 25.7 1 2 0 -0.0059 15 0 0 0 8.90E+06 1.96E+06 - - - 1.323 0.9659 230117_WJC_METTL3_WT_vs_EV_F08.17718.17718.2 0.0577 14-May R.VFLWGSFR[166.11].D "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1020.5421 0.97 65621 17718 2 1020.539189 511.2783 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 9.72 3862.3 - 35224.6 - - - -2.8103 - 1.115 0.238 - 134.4 1 2 0 -0.0029 8 0 0 0 7.11E+05 7.31E+05 - - - 1.1263 0.9701 230117_WJC_METTL3_WT_vs_EV_F08.17720.17720.2 0.0016 26-Jun K.LFIYNPTTGEFLGR.T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1626.8406 1.74 65623 17720 2 1626.832001 814.4276 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3862.6 - 44476.8 - - - -5.2814 - 1.495 0.356 - 90.6 1 2 0 -0.0086 14 0 0 0 2.84E+06 1.63E+06 - - - 2.6768 0.9987 230117_WJC_METTL3_WT_vs_EV_F08.17723.17723.2 0.00371 28-May R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 4.57 65625 17723 2 1710.906397 856.4607 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3863 - 28880.1 - - - -0.2192 - 1.446 0.362 - 50.2 1 2 0 -0.0004 15 0 0 0 8.97E+06 1.96E+06 - - - 2.6213 0.9955 230117_WJC_METTL3_WT_vs_EV_F08.17762.17762.2 0.00203 26-Jun K.LFIYNPTTGEFLGR[166.11].T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1636.8489 1.68 65646 17762 2 1636.845574 819.4317 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3868.4 - 36034 - - - -2.0093 - 1.314 0.379 - 106.4 1 2 0 -0.0033 14 0 0 0 2.75E+06 1.63E+06 - - - 2.5245 1 230117_WJC_METTL3_WT_vs_EV_F08.17775.17775.2 5.58E-07 13/22 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 863.95 65651 17775 2 1603.760737 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3870.2 - 1.93E+06 - - - -1.9972 - 2.105 0.563 - 453.9 1 2 0 -0.0032 12 0 0 0 3.44E+08 3.99E+05 - - - 5.1567 0.9914 230117_WJC_METTL3_WT_vs_EV_F08.17781.17781.2 0.013 18-Jul K.FEELNMDLFR.S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1312.6122 1.38 65654 17781 2 1312.607992 657.3134 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.14 3871.1 - 0 - - - -3.1853 - 1.57 0.316 - 157.7 1 2 0 -0.0042 10 0 0 0 1.10E+06 8.01E+05 - - - 2.6328 0.9977 230117_WJC_METTL3_WT_vs_EV_F08.17795.17795.2 0.176 20-Jun K.SGAYLIPLLER.L "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1230.6972 1.42 65660 17795 2 1230.697238 616.3559 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.72 3873.1 - 21321.5 - - - 0.0122 - 1.455 0.256 - 126.8 1 2 0 0 11 0 0 0 1.99E+06 1.41E+06 - - - 1.9463 0.9915 230117_WJC_METTL3_WT_vs_EV_F08.17799.17799.2 0.00806 20-Jun K.SGAYLIPLLER[166.11].L "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1240.7055 1.42 65662 17799 2 1240.706904 621.36 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.72 3873.7 - 9898.81 - - - 1.1373 - 1.32 0.108 - 153.2 1 2 0 0.0014 11 0 0 0 1.99E+06 1.41E+06 - - - 0.5893 0.9954 230117_WJC_METTL3_WT_vs_EV_F08.17807.17807.3 0.00215 Jul-64 K.IIHDFPQFYPLGIVQHD.- "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 2038.0312 - 65666 17807 3 2038.022353 680.351 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 5.22 3874.8 - 100448 - - - -4.3645 - 1.428 0.459 - 34.6 1 2 0 -0.0089 17 0 0 0 - - - - - 4.555 0.9977 230117_WJC_METTL3_WT_vs_EV_F08.17844.17844.2 0.000228 24-Aug R.LLSFSPEEFPTLK[136.11].A sp|Q5JSZ5|PRC2B_HUMAN 1 1514.8112 1.64 65682 17844 2 1514.817061 758.4129 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3880.1 - 26386.5 - - - 3.8711 - 1.633 0.336 - 178.6 1 2 0 0.0059 13 0 0 0 2.11E+06 1.29E+06 - - - 2.7795 0.9996 230117_WJC_METTL3_WT_vs_EV_F08.17848.17848.2 2.24E-05 24-Nov R.LLSFSPEEFPTLK.A sp|Q5JSZ5|PRC2B_HUMAN 1 1506.797 1.64 65683 17848 2 1506.801147 754.4058 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3880.7 - 164427 - - - 2.7542 - 1.95 0.508 - 385.3 1 2 0 0.0042 13 0 0 0 2.11E+06 1.29E+06 - - - 4.5058 1 230117_WJC_METTL3_WT_vs_EV_F08.17849.17849.2 7.06E-05 13/26 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.44 65684 17849 2 1672.87674 837.4479 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3880.9 - 153458 - - - -2.6816 - 2.886 0.566 - 641.9 1 2 0 -0.0045 14 0 0 0 4.26E+06 9.80E+06 - - - 5.8798 0.9998 230117_WJC_METTL3_WT_vs_EV_F08.17850.17850.3 4.80E-05 14/52 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.45 65685 17850 3 1672.878267 558.6344 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3881 - 169254 - - - -1.7688 - 2.645 0.511 - 336.1 1 2 0 -0.003 14 0 0 0 2.49E+06 5.52E+06 - - - 6.8212 0.9996 230117_WJC_METTL3_WT_vs_EV_F08.17851.17851.3 3.95E-05 Oct-52 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.45 65686 17851 3 1662.869462 555.2983 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3881.1 - 65558.6 - - - -2.1012 - 2.176 0.461 - 175.4 1 2 0 -0.0035 14 0 0 0 2.49E+06 5.52E+06 - - - 5.7449 0.999 230117_WJC_METTL3_WT_vs_EV_F08.17853.17853.3 0.00113 Jul-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 571.78 65687 17853 3 1603.760826 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3881.4 - 95101.3 - - - -1.9417 - 1.52 0.438 - 59.6 1 2 0 -0.0031 12 0 0 0 3.48E+07 6.08E+04 - - - 4.583 1 230117_WJC_METTL3_WT_vs_EV_F08.17855.17855.2 5.68E-08 15/26 K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.44 65688 17855 2 1662.871617 832.4438 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3881.6 - 141173 - - - -0.8052 - 3.116 0.565 - 1019.4 1 2 0 -0.0013 14 0 0 0 4.26E+06 9.80E+06 - - - 6.0658 0.9916 230117_WJC_METTL3_WT_vs_EV_F08.17858.17858.2 0.0539 18-Apr K.FGVFNYSPFR.T "sp|Q9ULU4|PKCB1_HUMAN,tr|A0A087WVZ6|A0A087WVZ6_HUMAN,tr|H7C4X9|H7C4X9_HUMAN,tr|A0A087WYS3|A0A087WYS3_HUMAN,tr|A0A087WV57|A0A087WV57_HUMAN" 5 1232.5978 1.3 65690 17858 2 1232.59597 617.3062 Protein kinase C-binding protein 1 OS=Homo sapiens OX=9606 GN=ZMYND8 PE=1 SV=2 8.75 3881.9 - 33526.3 - - - -1.5204 - 1.091 0.317 - 60 1 2 0 -0.0019 10 0 0 0 2.64E+05 2.03E+05 - - - 1.6249 0.9196 230117_WJC_METTL3_WT_vs_EV_F08.17865.17865.2 0.0469 26-May R.YAIQLITAASLVC[160.03]R.K sp|Q9Y230|RUVB2_HUMAN 1 1577.8599 -1 65695 17865 2 1577.853811 789.9373 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 8.22 3882.9 - 0 - - - -3.8901 - 1.005 0.257 - 77.1 1 2 0 -0.0061 14 0 0 0 0.00E+00 0.00E+00 - - - 0.9498 0.9979 230117_WJC_METTL3_WT_vs_EV_F08.17871.17871.2 3.37E-05 Jun-34 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.85 65700 17871 2 1936.006816 969.0131 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3883.6 - 41015.3 - - - -2.4654 - 1.644 0.519 - 102.1 1 2 0 -0.0048 18 0 0 0 2.03E+06 2.38E+06 - - - 4.0951 1 230117_WJC_METTL3_WT_vs_EV_F08.17876.17876.2 5.62E-07 14/26 K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.8 65703 17876 2 1651.929858 826.9731 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3884.3 - 168231 - - - -1.083 - 2.653 0.581 - 611.9 1 2 0 -0.0018 14 0 0 0 2.73E+06 3.43E+06 - - - 5.7802 1 230117_WJC_METTL3_WT_vs_EV_F08.17877.17877.2 3.16E-07 14/26 K.LYTLVTYVPVTTFK.N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1643.9174 0.8 65704 17877 2 1643.91643 822.966 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3884.4 - 128858 - - - -0.6186 - 2.592 0.553 - 632.5 1 2 0 -0.001 14 0 0 0 2.73E+06 3.43E+06 - - - 5.5152 1 230117_WJC_METTL3_WT_vs_EV_F08.17880.17880.2 9.79E-09 Dec-34 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.85 65705 17880 2 1925.997864 964.0089 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3884.9 - 116025 - - - -2.8323 - 2.627 0.631 - 340.6 1 2 0 -0.0055 18 0 0 0 2.03E+06 2.38E+06 - - - 6.0744 0.8582 230117_WJC_METTL3_WT_vs_EV_F08.17881.17881.2 0.171 22-Mar R.NFGASLLLPGLK[136.11].Q "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN,tr|D6RJC7|D6RJC7_HUMAN" 4 1236.7322 2.66 65706 17881 2 1236.727457 619.3734 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 8.75 3885 - 28113.7 - - - -3.802 - 0.715 0.311 - 28 1 2 0 -0.0047 12 0 0 0 7.96E+05 2.99E+05 - - - 0.4539 1 230117_WJC_METTL3_WT_vs_EV_F08.17882.17882.2 4.32E-06 26-Sep K.LFSLELVDESGEIR[166.11].A sp|P27694|RFA1_HUMAN 1 1615.8333 0.03 65707 17882 2 1615.829761 808.9239 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4 3885.1 - 135558 - - - -2.1735 - 2.195 0.5 - 327.4 1 2 0 -0.0035 14 0 0 0 4.05E+04 1.16E+06 - - - 4.7058 1 230117_WJC_METTL3_WT_vs_EV_F08.17883.17883.3 8.90E-06 13/68 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.7 65708 17883 3 1936.007527 646.3445 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3885.3 - 107840 - - - -2.0981 - 2.488 0.628 - 191.3 1 2 0 -0.0041 18 0 0 0 1.74E+06 2.49E+06 - - - 7.8101 1 230117_WJC_METTL3_WT_vs_EV_F08.17886.17886.3 3.56E-08 13/68 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.7 65709 17886 3 1926.003715 643.0084 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3885.7 - 45387.1 - - - 0.2056 - 2.041 0.583 - 149.1 1 2 0 0.0004 18 0 0 0 1.74E+06 2.49E+06 - - - 6.8163 0.9898 230117_WJC_METTL3_WT_vs_EV_F08.17895.17895.2 0.00198 18-Jun K.DWVFLNYTYK[136.11].R "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN" 2 1355.6641 0.29 65714 17895 2 1355.65809 678.8393 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.83 3887 - 52148.2 - - - -4.462 - 1.34 0.488 - 122.2 1 2 0 -0.006 10 0 0 0 1.36E+05 4.67E+05 - - - 3.4604 0.9947 230117_WJC_METTL3_WT_vs_EV_F08.17897.17897.2 0.000871 22-Jun R.LFQVEYAIEAIK.L sp|P28066|PSA5_HUMAN 1 1422.7759 2.86 65716 17897 2 1422.771763 712.3952 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 4.53 3887.2 - 84315 - - - -2.8852 - 1.462 0.401 - 107.1 1 2 0 -0.0041 12 0 0 0 8.98E+05 3.14E+05 - - - 3.0008 0.9247 230117_WJC_METTL3_WT_vs_EV_F08.17907.17907.2 2.18 20-Jun K.IALLNVELELK.A sp|Q99832|TCPH_HUMAN 1 1253.7595 22.93 65723 17907 2 1253.75789 627.887 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.53 3888.5 - 48026.4 - - - -1.2754 - 1.326 0.045 - 115.9 4 2 0 -0.0016 11 0 0 0 1.45E+06 6.34E+04 - - - -0.1327 0.9996 230117_WJC_METTL3_WT_vs_EV_F08.17927.17927.2 0.00211 26-May R.VIVSDVQESFIWVR[166.11].Y sp|Q15393|SF3B3_HUMAN 1 1685.9016 2.37 65734 17927 2 1685.903787 843.9581 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3891.3 - 53259.8 - - - 1.2812 - 1.432 0.493 - 43.2 1 2 0 0.0022 14 0 0 0 1.18E+06 4.97E+05 - - - 3.5827 0.9554 230117_WJC_METTL3_WT_vs_EV_F08.17928.17928.2 0.0655 20-Apr R.EALDVLGAVLK.A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1126.6598 1.59 65735 17928 2 1126.657786 564.3372 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3891.4 - 43297.4 - - - -1.7654 - 0.944 0.211 - 46 1 2 0 -0.002 11 0 0 0 4.76E+05 3.00E+05 - - - 0.4429 0.8861 230117_WJC_METTL3_WT_vs_EV_F08.17951.17951.2 0.223 14-Apr K.NFAFLEFR[166.11].S "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1052.5319 1.09 65748 17951 2 1052.52894 527.2732 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3894.6 - 39595.4 - - - -2.799 - 0.872 0.213 - 82.2 1 2 0 -0.0029 8 0 0 0 9.27E+05 8.50E+05 - - - 0.2002 0.997 230117_WJC_METTL3_WT_vs_EV_F08.17968.17968.2 0.0731 24-Apr K.VFSATLGLVDIVK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1368.8108 1.18 65758 17968 2 1368.810629 685.4127 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3897.1 - 11184.8 - - - -0.1271 - 1.074 0.343 - 35.6 1 2 0 -0.0002 13 0 0 0 2.22E+06 1.87E+06 - - - 1.7576 0.9981 230117_WJC_METTL3_WT_vs_EV_F08.17974.17974.2 0.000877 16-Aug R.DIDAFWLQR.Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1162.5771 1.58 65760 17974 2 1162.574301 582.2958 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3897.9 - 47705.7 - - - -2.4145 - 1.793 0.469 - 237.6 1 2 0 -0.0028 9 0 0 0 9.72E+05 6.16E+05 - - - 4.1934 0.9988 230117_WJC_METTL3_WT_vs_EV_F08.17989.17989.2 0.00232 22-Jul K.IILDLISESPIK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1347.8105 1.24 65768 17989 2 1347.808929 674.9125 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3900.1 - 28477.3 - - - -1.1426 - 1.783 0.407 - 120.3 1 2 0 -0.0015 12 0 0 0 6.88E+06 5.55E+06 - - - 3.5682 0.9937 230117_WJC_METTL3_WT_vs_EV_F08.17990.17990.2 0.556 28-Apr K.IVFVPGC[160.03]SIPLTIVK.S sp|P54136|SYRC_HUMAN 1 1641.9528 1.81 65769 17990 2 1641.954949 821.9837 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3900.3 - 24470.1 - - - 1.3167 - 0.975 0.247 - 49.7 1 2 0 0.0022 15 0 0 0 3.54E+05 1.95E+05 - - - 0.8024 1 230117_WJC_METTL3_WT_vs_EV_F08.17996.17996.2 0.000126 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 863.95 65774 17996 2 1603.761558 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3901.2 - 201298 - - - -1.4853 - 1.912 0.522 - 225.4 1 2 0 -0.0024 12 0 0 0 3.44E+08 3.99E+05 - - - 4.6011 0.9992 230117_WJC_METTL3_WT_vs_EV_F08.17999.17999.2 0.0038 26-Jun K.FGGDFLVYPGDPLR.F "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN" 4 1551.7722 5.8 65775 17999 2 1551.772934 776.8934 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.21 3901.6 - 45867.6 - - - 0.4865 - 1.382 0.41 - 104.1 1 2 0 0.0008 14 0 0 0 1.19E+06 2.06E+05 - - - 2.8809 0.9988 230117_WJC_METTL3_WT_vs_EV_F08.18010.18010.2 0.000585 24-Oct K.VFSATLGLVDIVK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1360.7966 1.18 65781 18010 2 1360.794106 681.4056 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3903.2 - 110765 - - - -1.835 - 1.835 0.512 - 220.6 1 2 0 -0.0025 13 0 0 0 2.22E+06 1.87E+06 - - - 4.3798 0.9839 230117_WJC_METTL3_WT_vs_EV_F08.18017.18017.2 0.2 24-Apr R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 1.49 65785 18017 2 1448.788784 725.4024 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3904.2 - 50010.2 - - - -1.0367 - 0.909 0.279 - 42.6 1 2 0 -0.0015 13 0 0 0 6.00E+06 4.04E+06 - - - 0.8563 0.9986 230117_WJC_METTL3_WT_vs_EV_F08.18019.18019.2 4.09E-05 24-Jul R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.48 65786 18019 2 1438.779068 720.3983 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3904.5 - 5898.97 - - - -2.049 - 1.858 0.515 - 192.2 1 2 0 -0.0029 13 0 0 0 6.00E+06 4.05E+06 - - - 4.4338 0.8502 230117_WJC_METTL3_WT_vs_EV_F08.18023.18023.2 5.56 26-Feb K.VLLLSSPGLEELYR.C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1587.8872 1.05 65788 18023 2 1587.886812 794.9509 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3905 - 17406.4 - - - -0.25 - 0.616 0.194 - 14.5 4 2 0 -0.0004 14 0 0 0 7.10E+05 6.75E+05 - - - -1.011 0.9989 230117_WJC_METTL3_WT_vs_EV_F08.18027.18027.2 0.00216 16-Jul R.FWYFVSQLK.K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1216.6281 0.76 65790 18027 2 1216.626774 609.3213 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3905.6 - 122647 - - - -1.0743 - 1.475 0.469 - 178.9 1 2 0 -0.0013 9 0 0 0 6.73E+06 8.88E+06 - - - 3.629 1 230117_WJC_METTL3_WT_vs_EV_F08.18109.18109.2 3.38E-05 26-Jul R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.08 65827 18109 2 1470.880042 736.4478 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3917.5 - 28800.1 - - - -0.652 - 1.629 0.62 - 99.2 1 2 0 -0.001 14 0 0 0 9.40E+05 8.69E+05 - - - 4.8445 0.998 230117_WJC_METTL3_WT_vs_EV_F08.18110.18110.2 0.00661 26-Jul R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.08 65828 18110 2 1478.893714 740.4549 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3917.6 - 25731.7 - - - -1.0055 - 1.465 0.371 - 96.1 1 2 0 -0.0015 14 0 0 0 9.40E+05 8.69E+05 - - - 2.739 1 230117_WJC_METTL3_WT_vs_EV_F08.18114.18114.2 3.10E-05 13/22 K.WLAPDGLIFPDR[166.11].A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1408.7379 0.87 65830 18114 2 1408.738517 705.3762 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3918.2 - 181707 - - - 0.4692 - 2.473 0.549 - 638.6 1 2 0 0.0007 12 0 0 0 4.08E+06 4.70E+06 - - - 5.4781 0.9995 230117_WJC_METTL3_WT_vs_EV_F08.18117.18117.2 0.000722 22-Sep K.WLAPDGLIFPDR.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1398.7296 0.87 65833 18117 2 1398.728826 700.3721 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3918.6 - 116709 - - - -0.5434 - 2.223 0.452 - 253 1 2 0 -0.0008 12 0 0 0 4.08E+06 4.70E+06 - - - 4.4812 0.9999 230117_WJC_METTL3_WT_vs_EV_F08.18119.18119.3 0.000463 7/112 R.RAEQDSTTVAAFASSLVSGLNSSASEPAK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2880.4101 4.84 65835 18119 3 2880.411346 961.144 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3918.8 - 59934.7 - - - 0.4291 - 1.6 0.514 - 40.6 1 2 0 0.0012 29 0 0 0 3.92E+05 8.12E+04 - - - 5.3516 1 230117_WJC_METTL3_WT_vs_EV_F08.18136.18136.2 4.62E-08 30-Dec K.LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1793.9075 0.98 65848 18136 2 1793.906186 897.961 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3921.1 - 49753 - - - -0.7325 - 2.65 0.589 - 345.8 1 2 0 -0.0013 16 0 0 0 1.36E+06 1.39E+06 - - - 5.7869 1 230117_WJC_METTL3_WT_vs_EV_F08.18137.18137.2 3.47E-12 15/30 K.LFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1783.8992 0.98 65849 18137 2 1783.896608 892.9569 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3921.3 - 43647.9 - - - -1.4698 - 3.228 0.636 - 714.8 1 2 0 -0.0026 16 0 0 0 1.36E+06 1.39E+06 - - - 6.6188 0.9969 230117_WJC_METTL3_WT_vs_EV_F08.18149.18149.2 0.000229 20-Jun R.LFEFAGYDVLR[166.11].L sp|P54136|SYRC_HUMAN 1 1338.6848 1.33 65856 18149 2 1338.682454 670.3497 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3923 - 44436.8 - - - -1.7211 - 1.65 0.32 - 104.8 1 2 0 -0.0023 11 0 0 0 2.36E+06 1.77E+06 - - - 2.7585 1 230117_WJC_METTL3_WT_vs_EV_F08.18168.18168.2 1.02E-05 20-Nov R.LFEFAGYDVLR.L sp|P54136|SYRC_HUMAN 1 1328.6765 1.33 65865 18168 2 1328.675713 665.3455 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3925.5 - 57699.8 - - - -0.5833 - 2.348 0.558 - 522.6 1 2 0 -0.0008 11 0 0 0 2.36E+06 1.77E+06 - - - 5.4712 0.9953 230117_WJC_METTL3_WT_vs_EV_F08.18189.18189.2 0.00393 20-May R.SVVTVIDVFYK.Y sp|Q5D862|FILA2_HUMAN 1 1268.7016 16.85 65873 18189 2 1268.699599 635.3581 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 5.55 3928.5 - 34421.7 - - - -1.6087 - 1.178 0.37 - 84.4 1 2 0 -0.002 11 0 0 0 1.26E+06 7.46E+04 - - - 2.2163 0.9636 230117_WJC_METTL3_WT_vs_EV_F08.18190.18190.3 0.00401 5/124 R.AEQDSTTVAAFASSLVSGLNSSASEPAKEPAK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3149.5364 4.82 65874 18190 3 3149.535477 1050.8528 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3928.6 - 30712.8 - - - -0.3032 - 1.32 0.452 - 11.4 1 2 1 -0.001 32 0 0 0 5.19E+05 1.08E+05 - - - 4.2178 1 230117_WJC_METTL3_WT_vs_EV_F08.18199.18199.2 2.49E-06 20-Aug K.YPSPFFVFGEK[136.11].L sp|Q08211|DHX9_HUMAN 1 1324.6583 1.01 65880 18199 2 1324.654704 663.3364 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3929.9 - 95967.9 - - - -2.7335 - 1.908 0.59 - 270.2 1 2 0 -0.0036 11 0 0 0 7.67E+06 7.62E+06 - - - 5.1453 1 230117_WJC_METTL3_WT_vs_EV_F08.18200.18200.2 5.56E-10 30-Nov K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 0.98 65881 18200 2 1807.91831 904.9689 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3930 - 86415.4 - - - -2.6771 - 2.67 0.665 - 305.2 1 2 0 -0.0048 16 0 0 0 4.07E+06 4.15E+06 - - - 6.3657 1 230117_WJC_METTL3_WT_vs_EV_F08.18202.18202.2 1.06E-06 22-Aug R.FSTFFDDAPVFR.L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1447.6772 2.07 65882 18202 2 1447.673704 724.8459 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3930.2 - 62898.8 - - - -2.426 - 1.817 0.544 - 255.2 1 2 0 -0.0035 12 0 0 0 5.46E+05 2.63E+05 - - - 4.6292 1 230117_WJC_METTL3_WT_vs_EV_F08.18203.18203.2 1.12E-07 30-Dec K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 0.98 65883 18203 2 1797.909455 899.9647 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3930.4 - 61612.6 - - - -3.0174 - 2.62 0.683 - 352.2 1 2 0 -0.0054 16 0 0 0 4.07E+06 4.15E+06 - - - 6.4519 1 230117_WJC_METTL3_WT_vs_EV_F08.18205.18205.2 3.18E-07 20-Oct K.YPSPFFVFGEK.L sp|Q08211|DHX9_HUMAN 1 1316.6441 1.01 65884 18205 2 1316.639823 659.3293 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3930.6 - 54352.4 - - - -3.2674 - 2.065 0.585 - 397.7 1 2 0 -0.0043 11 0 0 0 7.67E+06 7.62E+06 - - - 5.3221 0.9947 230117_WJC_METTL3_WT_vs_EV_F08.18212.18212.2 0.000229 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 65888 18212 2 1603.757513 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3931.5 - 93541.5 - - - -4.0074 - 1.831 0.481 - 201.4 1 2 0 -0.0064 12 0 0 0 4.24E+06 0.00E+00 - - - 4.1831 0.9992 230117_WJC_METTL3_WT_vs_EV_F08.18213.18213.3 0.000302 Sep-60 K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 1.13 65889 18213 3 1797.910063 600.3122 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3931.6 - 146957 - - - -2.6792 - 2.039 0.445 - 127.8 1 2 0 -0.0048 16 0 0 0 7.85E+05 6.97E+05 - - - 5.328 0.9997 230117_WJC_METTL3_WT_vs_EV_F08.18214.18214.3 1.57E-05 Jul-60 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 1.13 65890 18214 3 1807.920436 603.6483 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3931.7 - 109539 - - - -1.5012 - 1.652 0.503 - 66.3 1 2 0 -0.0027 16 0 0 0 7.85E+05 6.97E+05 - - - 5.4352 0.99 230117_WJC_METTL3_WT_vs_EV_F08.18215.18215.2 5.84E-05 22-Jun R.FSTFFDDAPVFR[166.11].L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1457.6855 2.07 65891 18215 2 1457.678432 729.85 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3931.9 - 49715.8 - - - -4.8392 - 1.507 0.512 - 129 1 2 0 -0.0071 12 0 0 0 5.46E+05 2.63E+05 - - - 3.8995 1 230117_WJC_METTL3_WT_vs_EV_F08.18221.18221.2 0.000636 24-Jul K.TPFLLVGTQIDLR.D "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 1471.8399 2.18 65895 18221 2 1471.837539 736.9272 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 5.5 3932.6 - 22114.5 - - - -1.5803 - 1.779 0.581 - 175.3 1 2 0 -0.0023 13 0 0 0 1.04E+05 4.78E+04 - - - 4.81 0.9973 230117_WJC_METTL3_WT_vs_EV_F08.18230.18230.2 0.000342 14-Jul R.GFGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 921.5204 1.12 65899 18230 2 921.518154 461.7675 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3933.9 - 475943 - - - -2.4101 - 1.482 0.447 - 152 1 2 0 -0.0022 8 0 0 0 1.55E+07 1.38E+07 - - - 3.5283 0.9975 230117_WJC_METTL3_WT_vs_EV_F08.18231.18231.2 0.000575 14-Aug R.GFGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 913.5062 1.12 65900 18231 2 913.504002 457.7604 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3934 - 478753 - - - -2.3787 - 1.482 0.464 - 208.6 1 2 0 -0.0022 8 0 0 0 1.55E+07 1.38E+07 - - - 3.6539 0.9997 230117_WJC_METTL3_WT_vs_EV_F08.18248.18248.2 8.28E-05 22-Jul K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 505.14 65909 18248 2 1459.794488 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3936.5 - 50831.5 - - - 1.5358 - 1.672 0.476 - 207.9 1 2 0 0.0022 12 0 0 0 1.49E+07 2.94E+04 - - - 3.9085 0.9953 230117_WJC_METTL3_WT_vs_EV_F08.18254.18254.2 0.0265 30-Apr R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 999 65913 18254 2 1796.002695 899.0095 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3937.3 - 26761.6 - - - -0.9293 - 1.122 0.336 - 32.6 1 2 0 -0.0017 16 0 0 0 1.08E+06 0.00E+00 - - - 1.8052 0.9969 230117_WJC_METTL3_WT_vs_EV_F08.18276.18276.3 0.0688 May-60 R.ELFEQYGAVYEINVLR.D "sp|Q92879|CELF1_HUMAN,tr|F5H4Y5|F5H4Y5_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PSH0|E9PSH0_HUMAN,tr|E9PQK4|E9PQK4_HUMAN,tr|E9PKA1|E9PKA1_HUMAN,tr|E9PKU1|E9PKU1_HUMAN,tr|F5H0D8|F5H0D8_HUMAN" 8 1941.9836 5.14 65921 18276 3 1941.984303 648.3352 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 4.25 3940.8 - 56148.3 - - - 0.3471 - 1.204 0.305 - 32.2 1 2 0 0.0007 16 0 0 0 4.17E+05 8.12E+04 - - - 2.4166 1 230117_WJC_METTL3_WT_vs_EV_F08.18277.18277.2 8.27E-08 30-Sep R.ELFEQYGAVYEINVLR.D "sp|Q92879|CELF1_HUMAN,tr|F5H4Y5|F5H4Y5_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PSH0|E9PSH0_HUMAN,tr|E9PQK4|E9PQK4_HUMAN,tr|E9PKA1|E9PKA1_HUMAN,tr|E9PKU1|E9PKU1_HUMAN,tr|F5H0D8|F5H0D8_HUMAN" 8 1941.9836 4.2 65922 18277 2 1941.986365 971.9991 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 4.25 3940.9 - 40949.5 - - - 1.4089 - 2.293 0.651 - 252.5 1 2 0 0.0027 16 0 0 0 2.44E+05 5.81E+04 - - - 5.8887 0.9989 230117_WJC_METTL3_WT_vs_EV_F08.18313.18313.2 0.00018 28-Jul K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 5.76 65938 18313 2 1591.942788 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3946.1 - 42357.7 - - - -1.3889 - 1.89 0.448 - 117.2 1 2 0 -0.0022 15 0 0 0 7.32E+06 1.27E+06 - - - 3.9143 0.9972 230117_WJC_METTL3_WT_vs_EV_F08.18338.18338.2 0.000125 26-Oct K.GYAFIEFASFEDAK.E "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 10 1593.7351 0.36 65949 18338 2 1593.730522 797.8748 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.14 3949.6 - 104701 - - - -2.8882 - 1.548 0.529 - 157.9 1 2 0 -0.0046 14 0 0 0 1.77E+06 4.93E+06 - - - 4.0433 1 230117_WJC_METTL3_WT_vs_EV_F08.18341.18341.4 2.67E-07 14/204 R.KIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 3974.1279 2.29 65950 18341 4 3974.11823 994.5392 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.01 3950 - 118698 - - - -2.4305 - 3.098 0.596 - 53.7 1 2 0 -0.0097 35 0 0 0 5.96E+05 2.60E+05 - - - 4.7461 0.9975 230117_WJC_METTL3_WT_vs_EV_F08.18346.18346.3 0.001 Jun-72 R.GPLLVQDVVFTDEMAHFDR.E sp|P04040|CATA_HUMAN 1 2188.0623 30.75 65953 18346 3 2188.05778 730.3614 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 4.22 3950.7 - 38218.6 - - - -2.0612 - 1.369 0.399 - 45.2 1 2 0 -0.0045 19 0 0 0 8.90E+05 2.89E+04 - - - 3.7588 0.9996 230117_WJC_METTL3_WT_vs_EV_F08.18352.18352.3 0.000335 6/116 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3096.5074 1.95 65956 18352 3 3096.500282 1033.1764 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 3951.5 - 31848.7 - - - -2.2926 - 1.322 0.596 - 23.7 1 2 0 -0.0071 30 0 0 0 2.59E+05 1.33E+05 - - - 5.8251 1 230117_WJC_METTL3_WT_vs_EV_F08.18357.18357.2 6.22E-05 24-Nov R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 2.45 65959 18357 2 1509.88634 755.9512 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3952.1 - 67257.3 - - - -1.0186 - 2.494 0.565 - 369.8 1 2 0 -0.0015 13 0 0 0 4.20E+05 1.71E+05 - - - 5.5591 1 230117_WJC_METTL3_WT_vs_EV_F08.18367.18367.2 0.195 20-Dec K.ILDVEIIFNER.G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1359.7398 1.29 65967 18367 2 1359.737164 680.8772 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3953.4 - 181282 - - - -1.9511 - 2.453 0.493 - 699.1 1 2 0 -0.0027 11 0 0 0 7.92E+05 6.16E+05 - - - 5.1089 1 230117_WJC_METTL3_WT_vs_EV_F08.18368.18368.2 1.62E-05 20-Dec K.ILDVEIIFNER[166.11].G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1369.7481 1.29 65968 18368 2 1369.747927 685.8813 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3953.5 - 95768.5 - - - -0.1168 - 2.482 0.522 - 655.2 1 2 0 -0.0002 11 0 0 0 7.92E+05 6.16E+05 - - - 5.3557 0.9995 230117_WJC_METTL3_WT_vs_EV_F08.18373.18373.2 0.000287 26-Apr R.IVEPYVTWGFPNLK[136.11].S "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1669.8959 1.09 65973 18373 2 1669.896566 835.9552 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6 3954.1 - 72169.7 - - - 0.3809 - 1.346 0.513 - 44.3 1 2 0 0.0006 14 0 0 0 2.89E+05 2.65E+05 - - - 3.5755 0.9913 230117_WJC_METTL3_WT_vs_EV_F08.18389.18389.2 0.0851 20-Apr K.DVLLPWYNAYR.F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1408.7139 2.03 65985 18389 2 1408.714807 705.3642 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3956.4 - 42884.4 - - - 0.6183 - 1.084 0.207 - 49 2 2 0 0.0009 11 0 0 0 8.84E+05 4.35E+05 - - - 0.6534 0.9842 230117_WJC_METTL3_WT_vs_EV_F08.18395.18395.2 0.135 20-May K.DVLLPWYNAYR[166.11].F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1418.7222 2.03 65989 18395 2 1418.72029 710.3684 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3957.1 - 52707.5 - - - -1.3505 - 1.176 0.209 - 98.3 1 2 0 -0.0019 11 0 0 0 8.84E+05 4.35E+05 - - - 1.0226 1 230117_WJC_METTL3_WT_vs_EV_F08.18401.18401.2 3.28E-07 26-Sep K.VVIGMDVAASEFFR.S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1539.7756 2.24 65993 18401 2 1539.776675 770.8951 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.37 3957.9 - 72648.4 - - - 0.7306 - 2.105 0.557 - 243.4 1 2 0 0.0011 14 0 0 0 1.50E+06 6.71E+05 - - - 5.0225 1 230117_WJC_METTL3_WT_vs_EV_F08.18402.18402.2 3.89E-05 18-Nov K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 36.56 65994 18402 2 1146.626296 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3958.1 - 60972.4 - - - -1.9004 - 2.217 0.524 - 353.6 1 2 0 -0.0022 10 0 0 0 8.87E+05 2.43E+04 - - - 5.1329 1 230117_WJC_METTL3_WT_vs_EV_F08.18406.18406.2 1.41E-10 13/34 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 14.82 65996 18406 2 1911.944965 956.9806 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3958.6 - 85756 - - - -0.8421 - 3.09 0.708 - 574.9 1 2 0 -0.0016 18 0 0 0 2.33E+06 1.57E+05 - - - 7.0434 0.9988 230117_WJC_METTL3_WT_vs_EV_F08.18432.18432.2 0.000156 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 77.94 66013 18432 2 1603.762054 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3962 - 34197.8 - - - -1.176 - 1.488 0.468 - 175.9 1 2 0 -0.0019 12 0 0 0 1.12E+06 1.43E+04 - - - 3.5428 1 230117_WJC_METTL3_WT_vs_EV_F08.18472.18472.4 1.19E-14 23/198 K.IELFGRPHNVQPNWITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 3846.0329 5.24 66038 18472 4 3846.027076 962.5155 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.26 3967.3 - 64546.8 - - - -1.521 - 4.359 0.712 - 178.7 1 2 0 -0.0059 34 0 0 0 1.11E+06 2.12E+05 - - - 5.8607 0.9994 230117_WJC_METTL3_WT_vs_EV_F08.18473.18473.2 1.98E-05 28-Jul R.LGLEFFDQPAVPLAR[166.11].A "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1681.9067 1.36 66039 18473 2 1681.90559 841.9606 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 4.37 3967.5 - 40827.5 - - - -0.6671 - 1.576 0.54 - 154.4 1 2 0 -0.0011 15 0 0 0 6.96E+05 5.12E+05 - - - 4.1475 0.9967 230117_WJC_METTL3_WT_vs_EV_F08.18482.18482.2 0.00109 20-Jul K.TFSFAIPLIEK[136.11].L sp|Q9NR30|DDX21_HUMAN 1 1272.7209 1.02 66044 18482 2 1272.718092 637.3677 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.66 3968.6 - 58788.4 - - - -2.2259 - 1.32 0.444 - 102.7 1 2 0 -0.0028 11 0 0 0 1.03E+06 1.01E+06 - - - 3.0706 1 230117_WJC_METTL3_WT_vs_EV_F08.18486.18486.2 4.80E-10 13/26 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 1.67 66046 18486 2 1676.895209 839.4565 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3969.2 - 116217 - - - -1.9637 - 2.99 0.569 - 550.5 1 2 0 -0.0033 14 0 0 0 1.16E+06 6.95E+05 - - - 5.9911 1 230117_WJC_METTL3_WT_vs_EV_F08.18487.18487.4 8.51E-10 20/162 R.PHNVQPNWITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 3130.6312 2.41 66047 18487 4 3130.625512 783.6651 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.14 3969.3 - 128022 - - - -1.822 - 3.995 0.705 - 172.4 1 1 0 -0.0057 28 0 0 0 1.87E+06 7.77E+05 - - - 5.7908 1 230117_WJC_METTL3_WT_vs_EV_F08.18488.18488.2 0.000108 26-Oct M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 1.67 66048 18488 2 1686.903583 844.4607 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3969.5 - 89458.2 - - - -1.8904 - 2.5 0.498 - 301.5 1 2 0 -0.0032 14 0 0 0 1.16E+06 6.95E+05 - - - 5.0176 0.9862 230117_WJC_METTL3_WT_vs_EV_F08.18493.18493.2 0.109 22-Jul R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 999 66053 18493 2 1301.703922 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3970.1 - 25512.8 - - - -3.016 - 1.416 0.28 - 108.6 1 2 0 -0.0039 12 0 0 0 3.33E+05 0.00E+00 - - - 2.0231 0.9939 230117_WJC_METTL3_WT_vs_EV_F08.18537.18537.2 2.35E-06 18-Jul R.EALQYFYFLR.D "sp|Q8N1F7|NUP93_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 2 1348.6816 1.61 66074 18537 2 1348.675845 675.3481 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 6.1 3976.2 - 72891 - - - -4.2471 - 1.688 0.501 - 260.5 1 2 0 -0.0057 10 0 0 0 9.54E+05 5.91E+05 - - - 4.201 0.9713 230117_WJC_METTL3_WT_vs_EV_F08.18539.18539.3 1.65E-06 Nov-80 N.WITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 2344.2539 2.63 66075 18539 3 2344.252487 782.4253 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3976.4 - 74267.2 - - - -0.6155 - 2.394 0.543 - 104.6 1 1 0 -0.0014 21 0 0 0 1.46E+07 5.56E+06 - - - 6.6864 0.9843 230117_WJC_METTL3_WT_vs_EV_F08.18551.18551.2 0.0848 14-Jun R.GFGFILFK[136.11].D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 935.536 0.89 66082 18551 2 935.534691 468.7753 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3977.9 - 42054.6 - - - -1.4259 - 1.151 0.216 - 111.7 1 2 0 -0.0013 8 0 0 0 2.36E+06 2.65E+06 - - - 1.0601 0.9929 230117_WJC_METTL3_WT_vs_EV_F08.18562.18562.2 6.31E-05 20-Jul R.LWGLTEMFPER.V sp|Q9NS69|TOM22_HUMAN 1 1377.6751 4.57 66088 18562 2 1377.669295 689.8448 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 4.53 3979.2 - 76358.3 - - - -4.2194 - 1.727 0.446 - 173 1 2 0 -0.0058 11 0 0 0 7.39E+05 1.62E+05 - - - 3.8114 1 230117_WJC_METTL3_WT_vs_EV_F08.18567.18567.3 2.78E-07 19/80 N.WITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2354.2622 2.63 66091 18567 3 2355.25395 785.7613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3979.9 - 583604 - - - 421.2572 - 3.276 0.627 - 271.8 1 1 0 0.9918 21 0 0 0 1.46E+07 5.56E+06 - - - 8.1006 0.9867 230117_WJC_METTL3_WT_vs_EV_F08.18569.18569.2 0.0153 16-Jul K.EVWDYVFFK.E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PRP1|A0A6I8PRP1_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 1231.5914 1.55 66093 18569 2 1231.588047 616.803 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.37 3980.2 - 85956.5 - - - -2.6908 - 1.269 0.29 - 127.1 1 2 0 -0.0033 9 0 0 0 5.96E+05 3.84E+05 - - - 1.8711 0.9961 230117_WJC_METTL3_WT_vs_EV_F08.18570.18570.2 0.000951 16-Jun R.GYPTLLWFR.D sp|Q8NBS9|TXND5_HUMAN 1 1151.6128 2.61 66094 18570 2 1151.610644 576.8137 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 8.75 3980.3 - 51205.4 - - - -1.8418 - 1.321 0.37 - 149.9 1 2 0 -0.0021 9 0 0 0 4.05E+05 1.55E+05 - - - 2.5785 0.9985 230117_WJC_METTL3_WT_vs_EV_F08.18574.18574.3 0.000524 Sep-84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.63 66096 18574 3 2382.337976 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3980.9 - 25680.2 - - - -4.5841 - 2.189 0.513 - 93.8 1 2 0 -0.0109 22 0 0 0 8.60E+05 5.29E+05 - - - 6.1138 0.9941 230117_WJC_METTL3_WT_vs_EV_F08.18576.18576.2 0.0282 18-Jul R.ILGLLDAYLK[136.11].T sp|P26641|EF1G_HUMAN 1 1125.6889 0.9 66098 18576 2 1125.68668 563.8517 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3981.1 - 48024.5 - - - -1.9695 - 1.36 0.315 - 105.1 1 2 0 -0.0022 10 0 0 0 5.21E+05 5.78E+05 - - - 2.2252 0.9877 230117_WJC_METTL3_WT_vs_EV_F08.18581.18581.2 0.473 18-Jul R.ILGLLDAYLK.T sp|P26641|EF1G_HUMAN 1 1117.6747 0.9 66101 18581 2 1117.670701 559.8446 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3981.8 - 217706 - - - -3.5753 - 1.592 0.293 - 82.8 1 2 0 -0.004 10 0 0 0 5.21E+05 5.78E+05 - - - 2.5018 0.9991 230117_WJC_METTL3_WT_vs_EV_F08.18600.18600.3 0.000612 Jun-60 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 2.33 66118 18600 3 1751.863833 584.9623 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3984.3 - 73173 - - - -0.7535 - 1.258 0.431 - 32 1 2 0 -0.0013 16 0 0 0 1.79E+05 7.67E+04 - - - 3.9338 0.9981 230117_WJC_METTL3_WT_vs_EV_F08.18602.18602.2 0.00199 22-Jun R.LGPLLDILADSR.H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1281.7293 1.51 66120 18602 2 1281.728638 641.8719 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3984.5 - 43248.5 - - - -0.479 - 1.493 0.313 - 145.1 1 2 0 -0.0006 12 0 0 0 2.85E+05 1.89E+05 - - - 2.4072 0.9942 230117_WJC_METTL3_WT_vs_EV_F08.18606.18606.2 0.692 22-Jul K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 1.16 66122 18606 2 1344.860341 673.4385 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3985.1 - 105711 - - - -1.5645 - 1.762 0.197 - 159.3 1 2 0 -0.0021 12 0 0 0 2.48E+06 2.14E+06 - - - 1.9858 0.9968 230117_WJC_METTL3_WT_vs_EV_F08.18607.18607.2 0.0632 22-Aug K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 1.16 66123 18607 2 1336.844801 669.4314 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3985.2 - 115905 - - - -2.5762 - 1.728 0.4 - 215.1 1 2 0 -0.0034 12 0 0 0 2.48E+06 2.14E+06 - - - 3.4335 0.998 230117_WJC_METTL3_WT_vs_EV_F08.18616.18616.2 0.00363 20-May K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 1.12 66129 18616 2 1315.783464 658.9005 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3986.4 - 34147.9 - - - -2.2108 - 1.356 0.542 - 78.4 1 2 0 -0.0029 11 0 0 0 4.39E+05 3.93E+05 - - - 3.8671 1 230117_WJC_METTL3_WT_vs_EV_F08.18629.18629.2 1.88E-08 22-Dec K.TSDLIVLGLPWK.T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1340.7704 2.82 66137 18629 2 1340.768144 671.3925 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3988.2 - 119359 - - - -1.6737 - 2.552 0.574 - 545.2 1 2 0 -0.0022 12 0 0 0 1.16E+06 4.11E+05 - - - 5.7449 0.9908 230117_WJC_METTL3_WT_vs_EV_F08.18636.18636.2 0.0127 14-May R.LLFFWSDR.R "sp|Q9H6Z9|EGLN3_HUMAN,sp|Q9GZT9|EGLN1_HUMAN,tr|G3V3M1|G3V3M1_HUMAN,tr|F8W1G2|F8W1G2_HUMAN,tr|A0A590UJT7|A0A590UJT7_HUMAN,tr|A0A590UJ78|A0A590UJ78_HUMAN,tr|A0A590UJK7|A0A590UJK7_HUMAN" 7 1082.5549 5.39 66142 18636 2 1082.552591 542.2847 Prolyl hydroxylase EGLN3 OS=Homo sapiens OX=9606 GN=EGLN3 PE=1 SV=1 5.84 3989.2 - 22159.9 - - - -2.1477 - 1.03 0.375 - 87.9 1 2 0 -0.0023 8 0 0 0 1.82E+05 3.37E+04 - - - 1.8992 0.9964 230117_WJC_METTL3_WT_vs_EV_F08.18645.18645.3 3.67E-06 Sep-44 K.LREC[160.03]LPLIIFLR.N sp|P62701|RS4X_HUMAN 1 1541.9116 0.89 66145 18645 3 1541.912073 514.9778 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3990.3 - 61963 - - - 0.3132 - 2.177 0.546 - 199.3 1 2 1 0.0005 12 0 0 0 3.97E+06 4.48E+06 - - - 6.7836 0.978 230117_WJC_METTL3_WT_vs_EV_F08.18646.18646.3 0.0104 Jul-44 K.LR[166.11]EC[160.03]LPLIIFLR[166.11].N sp|P62701|RS4X_HUMAN 1 1561.9281 0.89 66146 18646 3 1561.927292 521.65 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3990.4 - 43254.8 - - - -0.5365 - 1.789 0.426 - 78 1 2 1 -0.0008 12 0 0 0 3.97E+06 4.48E+06 - - - 4.9015 0.8853 230117_WJC_METTL3_WT_vs_EV_F08.18654.18654.3 0.122 Mar-60 R.FLLPEYLPYAGIFHER.G "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1964.0196 3.06 66150 18654 3 1964.012827 655.6805 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 5.4 3991.5 - 32226.2 - - - -3.4587 - 0.877 0.305 - 10.7 2 2 0 -0.0068 16 0 0 0 1.16E+06 3.78E+05 - - - 1.4625 0.9996 230117_WJC_METTL3_WT_vs_EV_F08.18660.18660.2 5.73E-05 22-Jun R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 28.66 66153 18660 2 1603.764273 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3992.3 - 49065.1 - - - 0.2076 - 1.438 0.547 - 106.4 1 2 0 0.0003 12 0 0 0 3.71E+06 1.29E+05 - - - 4.0368 0.9996 230117_WJC_METTL3_WT_vs_EV_F08.18673.18673.3 0.000234 Aug-60 K.IFEIFGPVAHPFYVLR.F sp|Q96HR8|NAF1_HUMAN 1 1904.0349 1.72 66162 18673 3 1904.033302 635.6856 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 6.75 3994.1 - 65600.6 - - - -0.8267 - 1.734 0.439 - 73.9 1 2 0 -0.0016 16 0 0 0 1.16E+06 6.76E+05 - - - 4.8463 0.9998 230117_WJC_METTL3_WT_vs_EV_F08.18674.18674.3 1.06E-05 Nov-60 K.IFEIFGPVAHPFYVLR[166.11].F sp|Q96HR8|NAF1_HUMAN 1 1914.0431 1.72 66163 18674 3 1914.038716 639.0217 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 6.75 3994.2 - 39036.3 - - - -2.3145 - 2.636 0.537 - 162 1 2 0 -0.0044 16 0 0 0 1.16E+06 6.76E+05 - - - 7.0128 1 230117_WJC_METTL3_WT_vs_EV_F08.18686.18686.3 1.07E-05 Dec-52 R.HPYFYAPELLFFAK.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 1741.8868 999 66169 18686 3 1741.886363 581.6362 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6.75 3996 - 91982.2 - - - -0.2595 - 2.662 0.572 - 290.9 1 2 0 -0.0005 14 0 0 0 1.27E+06 0.00E+00 - - - 7.519 1 230117_WJC_METTL3_WT_vs_EV_F08.18690.18690.2 1.95E-08 26-Dec K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 35.52 66171 18690 2 1537.764407 769.8922 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3996.5 - 60371.3 - - - -3.5044 - 2.506 0.634 - 423.2 1 2 0 -0.0054 14 0 0 0 9.51E+05 2.68E+04 - - - 6.0274 0.9683 230117_WJC_METTL3_WT_vs_EV_F08.18700.18700.2 0.0454 16-Apr R.YEGFFSLWK.G "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 1175.5651 0.92 66177 18700 2 1175.56304 588.7898 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 6 3997.8 - 24655.8 - - - -1.7923 - 0.818 0.304 - 37.5 1 2 0 -0.0021 9 0 0 0 1.23E+05 1.34E+05 - - - 0.7045 0.9971 230117_WJC_METTL3_WT_vs_EV_F08.18702.18702.2 0.0136 24-Jul R.AIAYLFPSGLFEK[136.11].R sp|P82933|RT09_HUMAN 1 1462.7952 1.1 66178 18702 2 1462.797384 732.4049 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 6.05 3998.1 - 53436.1 - - - 1.5252 - 1.579 0.161 - 190.3 1 2 0 0.0022 13 0 0 0 4.29E+05 3.90E+05 - - - 1.4018 0.9991 230117_WJC_METTL3_WT_vs_EV_F08.18704.18704.2 0.0024 24-Jun R.AIAYLFPSGLFEK.R sp|P82933|RT09_HUMAN 1 1454.781 1.1 66180 18704 2 1454.782541 728.3978 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 6.05 3998.3 - 45005 - - - 1.0916 - 1.481 0.338 - 117.5 1 2 0 0.0016 13 0 0 0 4.29E+05 3.90E+05 - - - 2.5449 1 230117_WJC_METTL3_WT_vs_EV_F08.18714.18714.2 0.00155 17/28 R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 -1 66189 18714 2 1581.903802 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 3999.4 - 6.91E+06 - - - -3.2903 - 3.446 0.505 - 1070.5 1 2 0 -0.0052 15 0 0 0 0.00E+00 0.00E+00 - - - 5.811 0.9984 230117_WJC_METTL3_WT_vs_EV_F08.19156.19156.2 0.0181 16-Sep R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.4 66223 19156 2 1108.657624 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4076.1 - 631186 - - - 3.9607 - 1.781 0.35 - 213.5 1 2 0 0.0044 9 0 0 0 1.51E+06 1.08E+06 - - - 3.2945 1 230117_WJC_METTL3_WT_vs_EV_F08.19157.19157.2 0.00665 26-Nov R.RLNIPVLQDDGFLF.L sp|Q86U44|MTA70_HUMAN 1 1645.8828 59.04 66224 19157 2 1645.888685 823.9487 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 4076.2 - 561792 - - - 3.5804 - 2.357 0.477 - 356.1 1 1 0 0.0059 14 0 0 0 1.88E+06 3.18E+04 - - - 4.7138 0.9738 230117_WJC_METTL3_WT_vs_EV_F08.19444.19444.2 0.275 22-Jul R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 -1 66240 19444 2 1603.773725 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 4132.1 - 90582.8 - - - 6.1013 - 1.488 0.233 - 136.5 1 2 0 0.0098 12 0 0 0 0.00E+00 0.00E+00 - - - 1.8046 0.9986 230117_WJC_METTL3_WT_vs_EV_F09.02369.02369.2 0.163 12-Jul K.YDSTHGR.Y "sp|O14556|G3PT_HUMAN,tr|K7EP73|K7EP73_HUMAN" 2 834.362 -1 66248 2369 2 834.363003 418.1883 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 6.74 1182.1 - 505336 - - - 1.1662 - 1.431 0.258 - 202.9 1 2 0 0.001 7 0 0 0 0.00E+00 0.00E+00 - - - 2.0818 0.9878 230117_WJC_METTL3_WT_vs_EV_F09.07668.07668.3 0.407 Apr-60 K.ATAGDTHLGGEDFDNR.L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1674.7234 20.01 66314 7668 3 1674.723351 559.2484 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2183.2 - 19973.4 - - - -0.0239 - 0.821 0.319 - 20.1 1 2 0 0 16 0 0 0 1.11E+06 5.57E+04 - - - 1.5904 0.9996 230117_WJC_METTL3_WT_vs_EV_F09.09376.09376.2 0.000153 22-May R.AQVQEFC[160.03]DYGTK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1444.6293 1.78 66351 9376 2 1444.630905 723.3219 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2501.7 - 33166.4 - - - 1.1249 - 1.127 0.56 - 70.6 1 2 0 0.0016 12 0 0 0 2.30E+06 1.29E+06 - - - 3.4912 0.8745 230117_WJC_METTL3_WT_vs_EV_F09.10708.10708.2 4.80E-06 Jun-32 N.IVSNASC[160.03]TTNC[160.03]LAPLAK.V "sp|O14556|G3PT_HUMAN,tr|K7EP73|K7EP73_HUMAN" 2 1818.8968 999 66413 10708 2 1818.89237 910.4557 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 8.06 2745.1 - 32703.1 - - - -2.4383 - 1.344 0.631 - 74.6 1 1 0 -0.0044 17 0 0 0 1.84E+06 0.00E+00 - - - 4.427 1 230117_WJC_METTL3_WT_vs_EV_F09.10778.10778.3 4.00E-07 Sep-68 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 2.34 66416 10778 3 2070.865017 691.296 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2757.9 - 48724.7 - - - -0.6157 - 1.919 0.699 - 87 1 2 0 -0.0013 18 0 0 0 2.21E+06 9.44E+05 - - - 7.9559 0.9966 230117_WJC_METTL3_WT_vs_EV_F09.10995.10995.2 0.00242 20-Apr R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 3.73 66429 10995 2 1201.608462 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2797.2 - 25865.6 - - - -0.5617 - 0.875 0.436 - 61.6 1 2 0 -0.0007 11 0 0 0 6.07E+06 1.63E+06 - - - 1.8999 0.999 230117_WJC_METTL3_WT_vs_EV_F09.11078.11078.3 7.45E-05 Apr-96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 2.79 66436 11078 3 2559.239175 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2812 - 15714.3 - - - -0.812 - 0.962 0.487 - 10.4 1 2 0 -0.0021 25 0 0 0 4.70E+05 1.68E+05 - - - 3.8799 0.999 230117_WJC_METTL3_WT_vs_EV_F09.11361.11361.4 6.37E-05 8/108 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 1.61 66453 11361 4 2080.017569 521.0129 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2863.1 - 191774 - - - -2.3865 - 1.476 0.515 - 33.3 1 2 0 -0.005 19 0 0 0 6.39E+06 3.97E+06 - - - 3.8389 0.9873 230117_WJC_METTL3_WT_vs_EV_F09.12567.12567.2 1.6 26-Apr K.VPQVSTPTLVEVSR.N "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1510.8355 999 66541 12567 2 1510.834504 756.425 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.97 3077 - 129370 - - - -0.6645 - 0.992 0.249 - 37.1 1 2 0 -0.001 14 0 0 0 1.26E+07 0.00E+00 - - - 0.8596 0.9999 230117_WJC_METTL3_WT_vs_EV_F09.12733.12733.3 2.16E-07 13/128 R.SDSPVPTAPTSGGPKPSTASAVPELATDPELEK.K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3232.5987 5.8 66555 12733 3 3232.592203 1078.5402 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3105.8 - 18714.2 - - - -2.0092 - 2.857 0.591 - 66.8 1 2 0 -0.0065 33 0 0 0 5.97E+06 1.03E+06 - - - 7.5424 0.9908 230117_WJC_METTL3_WT_vs_EV_F09.13221.13221.2 0.0506 16-Apr R.AFGYYGPLR[166.11].S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1052.5319 0.98 66627 13221 2 1052.530916 527.2732 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3186.9 - 15614.9 - - - -0.9216 - 0.858 0.357 - 62.8 1 2 0 -0.001 9 0 0 0 2.54E+06 2.58E+06 - - - 1.2344 0.997 230117_WJC_METTL3_WT_vs_EV_F09.13232.13232.2 0.00866 16-May R.AFGYYGPLR.S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1042.5236 0.98 66631 13232 2 1042.522744 522.2691 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3188.6 - 42012.7 - - - -0.8364 - 1.052 0.402 - 92 1 2 0 -0.0009 9 0 0 0 2.53E+06 2.57E+06 - - - 2.1566 0.8513 230117_WJC_METTL3_WT_vs_EV_F09.13581.13581.2 5.16 14-Apr K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 1.82 66675 13581 2 895.478522 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3247.5 - 41762.4 - - - -2.0458 - 0.734 0.215 - 43.2 1 2 0 -0.0018 8 0 0 0 1.88E+06 1.03E+06 - - - -0.3043 0.9327 230117_WJC_METTL3_WT_vs_EV_F09.13738.13738.2 92.4 16-Apr R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 0.82 66692 13738 2 960.609495 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3274.4 - 48344.5 - - - -0.4403 - 0.86 0.136 - 65.2 1 2 0 -0.0004 9 0 0 0 3.77E+06 4.58E+06 - - - -0.391 0.9992 230117_WJC_METTL3_WT_vs_EV_F09.13863.13863.2 0.0032 18-Jun K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 15.55 66707 13863 2 1149.581674 575.7982 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3296 - 22416.3 - - - -0.1609 - 1.308 0.471 - 115.9 1 2 0 -0.0002 10 0 0 0 9.16E+05 5.89E+04 - - - 3.2692 0.9943 230117_WJC_METTL3_WT_vs_EV_F09.13940.13940.2 0.0137 18-Jun K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 2.26 66717 13940 2 1154.640036 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3308.7 - 134371 - - - -2.2856 - 1.379 0.342 - 89.5 1 2 0 -0.0026 10 0 0 0 3.13E+07 1.38E+07 - - - 2.4632 1 230117_WJC_METTL3_WT_vs_EV_F09.14228.14228.4 5.04E-08 10/126 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K.Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2674.0556 2.24 66753 14228 4 2674.056882 669.5212 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3357.4 - 70480.6 - - - 0.463 - 2.258 0.707 - 66.7 1 2 0 0.0012 22 0 0 0 1.58E+06 7.07E+05 - - - 5.6459 0.9836 230117_WJC_METTL3_WT_vs_EV_F09.14402.14402.2 0.015 14-Jun R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 70.09 66777 14402 2 1000.556243 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3386 - 61120.7 - - - -3.0883 - 1.41 0.247 - 134.3 1 2 0 -0.0031 8 0 0 0 6.05E+06 8.63E+04 - - - 1.9006 0.9501 230117_WJC_METTL3_WT_vs_EV_F09.14585.14585.2 1.2 16-Apr R.FAVGIVIGR.N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 930.5651 1.68 66815 14585 2 930.563685 466.2898 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3414.8 - 56677.5 - - - -1.5066 - 0.847 0.229 - 63.7 1 2 0 -0.0014 9 0 0 0 7.08E+05 4.21E+05 - - - 0.2515 0.995 230117_WJC_METTL3_WT_vs_EV_F09.14741.14741.2 0.000291 26-Jun R.GVVDSEDIPLNLSR.E "sp|Q12931|TRAP1_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 6 1512.7784 999 66833 14741 2 1512.772976 757.3965 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.03 3441.7 - 31419.4 - - - -3.5769 - 1.388 0.523 - 85.3 1 2 0 -0.0054 14 0 0 0 6.17E+06 0.00E+00 - - - 3.7249 0.9714 230117_WJC_METTL3_WT_vs_EV_F09.14831.14831.2 1.81 16-Jul R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 25.22 66845 14831 2 1006.566571 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3457.1 - 74437.7 - - - -3.3053 - 1.352 0.218 - 110.6 1 2 0 -0.0033 9 0 0 0 3.55E+08 1.41E+07 - - - 1.5226 0.9948 230117_WJC_METTL3_WT_vs_EV_F09.14862.14862.2 0.141 16-Jul R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 25.12 66851 14862 2 1014.580846 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3462.1 - 118856 - - - -3.2053 - 1.434 0.434 - 116.6 1 2 0 -0.0033 9 0 0 0 3.54E+08 1.41E+07 - - - 3.2884 0.9971 230117_WJC_METTL3_WT_vs_EV_F09.15020.15020.2 0.00318 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 1768.68 66881 15020 2 1006.567126 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3487.4 - 64216.6 - - - -2.7539 - 1.68 0.444 - 252 1 2 0 -0.0028 9 0 0 0 1.52E+07 8.57E+03 - - - 3.8204 0.9927 230117_WJC_METTL3_WT_vs_EV_F09.15037.15037.2 0.0108 26-May R.FTQAGSEVSALLGR.L "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1434.7467 999 66885 15037 2 1434.743703 718.3806 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6 3490 - 13720.2 - - - -2.084 - 1.013 0.407 - 57.3 1 2 0 -0.003 14 0 0 0 9.12E+05 0.00E+00 - - - 2.0786 0.9722 230117_WJC_METTL3_WT_vs_EV_F09.15064.15064.2 0.184 20-Apr R.IVLLDSSLEYK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1278.7071 8.48 66890 15064 2 1278.704518 640.3608 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3494.3 - 9175.34 - - - -2.0341 - 0.954 0.271 - 43.7 1 2 0 -0.0026 11 0 0 0 4.51E+06 5.31E+05 - - - 0.9144 0.9967 230117_WJC_METTL3_WT_vs_EV_F09.15123.15123.2 0.123 18-May R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 2.2 66900 15123 2 1348.609701 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3503.7 - 21470.4 - - - -0.9195 - 1.137 0.371 - 111 1 2 0 -0.0012 10 0 0 0 1.20E+07 5.43E+06 - - - 2.1392 1 230117_WJC_METTL3_WT_vs_EV_F09.15126.15126.2 0.000542 18-Jul R.EC[160.03]LNLWGYER.V sp|Q86U44|MTA70_HUMAN 1 1338.6027 2.21 66901 15126 2 1338.60157 670.3086 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3504.1 - 73341 - - - -0.8225 - 1.705 0.57 - 282.9 1 2 0 -0.0011 10 0 0 0 1.20E+07 5.43E+06 - - - 4.74 0.9421 230117_WJC_METTL3_WT_vs_EV_F09.15158.15158.3 0.0246 Mar-76 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 1.94 66910 15158 3 2187.031083 730.0199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3508.8 - 18180.6 - - - -3.1015 - 0.764 0.352 - 9.2 1 2 0 -0.0068 20 0 0 0 1.02E+07 5.25E+06 - - - 1.8095 0.8699 230117_WJC_METTL3_WT_vs_EV_F09.15170.15170.3 0.00335 Aug-76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 1.94 66912 15170 3 2198.042913 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3510.6 - 30357.2 - - - 453.6896 - 1.543 0.446 - 75.1 1 2 0 0.9968 20 0 0 0 1.02E+07 5.25E+06 - - - 4.2886 0.9932 230117_WJC_METTL3_WT_vs_EV_F09.15181.15181.2 0.00135 Apr-38 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 3.01 66913 15181 2 2187.031767 1094.5262 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3512.5 - 0 - - - -2.7887 - 1.117 0.448 - 30.6 1 2 0 -0.0061 20 0 0 0 3.48E+06 1.16E+06 - - - 2.62 1 230117_WJC_METTL3_WT_vs_EV_F09.15271.15271.2 5.89E-06 22-Jul K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 9.42 66935 15271 2 1332.73776 667.3774 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3527.2 - 18485.1 - - - -1.794 - 1.813 0.541 - 153.7 1 2 0 -0.0024 12 0 0 0 7.20E+06 7.65E+05 - - - 4.6016 0.9522 230117_WJC_METTL3_WT_vs_EV_F09.15304.15304.2 0.104 30-Mar R.IINEPTAAAIAYGLDK.R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1658.8879 90.2 66942 15304 2 1658.884763 830.4512 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3532.2 - 8306.3 - - - -1.9133 - 0.741 0.292 - 21.2 1 2 0 -0.0032 16 0 0 0 1.04E+06 1.15E+04 - - - 0.4598 0.9176 230117_WJC_METTL3_WT_vs_EV_F09.15619.15619.2 0.271 16-May R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 669.92 67015 15619 2 1006.565302 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3582.2 - 151846 - - - -4.566 - 0.936 0.326 - 66.6 1 2 0 -0.0046 9 0 0 0 4.16E+06 6.21E+03 - - - 1.256 1 230117_WJC_METTL3_WT_vs_EV_F09.15622.15622.2 9.32E-05 30-Aug K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 999 67017 15622 2 1789.877288 895.9496 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3582.6 - 68732.4 - - - -4.1092 - 1.802 0.592 - 177.4 1 2 0 -0.0074 16 0 0 0 4.75E+06 0.00E+00 - - - 4.859 0.9741 230117_WJC_METTL3_WT_vs_EV_F09.15700.15700.2 0.424 26-Apr K.NIYVLQELDNPGAK.R "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1572.8148 1.54 67038 15700 2 1572.812119 787.4147 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3594.3 - 23503.2 - - - -1.6868 - 0.951 0.256 - 55.7 1 2 0 -0.0027 14 0 0 0 7.32E+05 4.75E+05 - - - 0.8049 0.9958 230117_WJC_METTL3_WT_vs_EV_F09.15718.15718.2 0.092 20-Apr K.LVFLGLDNAGK.T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1145.6445 1.79 67043 15718 2 1145.645088 573.8295 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3597.2 - 32903.1 - - - 0.549 - 0.798 0.377 - 44.9 1 2 0 0.0006 11 0 0 0 6.36E+05 3.55E+05 - - - 1.2149 0.9842 230117_WJC_METTL3_WT_vs_EV_F09.15856.15856.2 4.38 20-Mar K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 1.13 67076 15856 2 1197.72045 599.8679 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3618.9 - 15851.3 - - - -0.6763 - 0.745 0.333 - 26.2 1 2 0 -0.0008 11 0 0 0 1.42E+06 1.26E+06 - - - 0.7039 0.9965 230117_WJC_METTL3_WT_vs_EV_F09.15874.15874.2 0.0141 20-May K.VANVSLLALYK.G sp|P62266|RS23_HUMAN 1 1189.7071 1.13 67080 15874 2 1189.705664 595.8608 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3622 - 94731.8 - - - -1.1734 - 1.179 0.37 - 71.4 1 2 0 -0.0014 11 0 0 0 1.42E+06 1.26E+06 - - - 2.2188 1 230117_WJC_METTL3_WT_vs_EV_F09.15875.15875.2 4.76E-05 18-Aug R.FEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1252.6088 7.69 67081 15875 2 1252.605398 627.3117 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3622.1 - 106774 - - - -2.7175 - 1.905 0.526 - 247 1 2 0 -0.0034 10 0 0 0 4.04E+06 5.25E+05 - - - 4.7239 0.9968 230117_WJC_METTL3_WT_vs_EV_F09.15938.15938.2 0.00461 16-Jun K.GFGFVSFER[166.11].H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1054.5112 0.94 67100 15938 2 1054.509483 528.2629 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3631.5 - 40561.4 - - - -1.5818 - 1.27 0.391 - 146.4 1 2 0 -0.0017 9 0 0 0 3.41E+06 3.63E+06 - - - 2.6199 0.9796 230117_WJC_METTL3_WT_vs_EV_F09.16102.16102.2 0.381 18-Apr R.LWIANYSLPR.A sp|O43172|PRP4_HUMAN 1 1231.6713 5.31 67133 16102 2 1231.669576 616.8429 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3657.5 - 38524.5 - - - -1.4346 - 0.879 0.296 - 53.4 1 2 0 -0.0018 10 0 0 0 5.38E+05 1.01E+05 - - - 0.8667 0.9736 230117_WJC_METTL3_WT_vs_EV_F09.16103.16103.2 0.678 16-Apr R.QINWTVLYR[166.11].R "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1201.6483 1.07 67134 16103 2 1201.646168 601.8314 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 8.75 3657.7 - 36430.7 - - - -1.785 - 0.968 0.256 - 48.2 1 2 0 -0.0021 9 0 0 0 4.63E+05 4.33E+05 - - - 0.8371 0.9902 230117_WJC_METTL3_WT_vs_EV_F09.16144.16144.2 0.000547 22-Jun K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 999 67147 16144 2 1252.749026 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3663.8 - 27211.8 - - - -1.0345 - 1.408 0.176 - 162.8 1 2 0 -0.0013 12 0 0 0 2.70E+06 0.00E+00 - - - 1.2408 0.9958 230117_WJC_METTL3_WT_vs_EV_F09.16157.16157.2 2.30E-05 20-May R.FFDEESYSLLR[166.11].K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1414.6644 1.7 67150 16157 2 1414.659278 708.3395 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3665.8 - 34865 - - - -3.632 - 1.262 0.609 - 45.5 1 2 0 -0.0051 11 0 0 0 1.06E+06 6.21E+05 - - - 4.167 0.9716 230117_WJC_METTL3_WT_vs_EV_F09.16346.16346.2 0.213 22-Apr K.DAGVIAGLNVLR.L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1196.6877 2.79 67190 16346 2 1196.68468 599.3511 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3697.4 - 51051.5 - - - -2.5412 - 1.137 0.239 - 58.7 1 2 0 -0.003 12 0 0 0 8.74E+05 3.13E+05 - - - 1.1431 1 230117_WJC_METTL3_WT_vs_EV_F09.16388.16388.2 2.91E-05 26-Sep K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.39 67203 16388 2 1762.791781 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3703.9 - 20966.1 - - - -1.8828 - 2.1 0.638 - 234.7 1 2 0 -0.0033 14 0 0 0 2.53E+06 1.81E+06 - - - 5.6141 1 230117_WJC_METTL3_WT_vs_EV_F09.16393.16393.2 6.09E-08 26-Sep K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.39 67206 16393 2 1772.807139 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3704.6 - 85820.5 - - - 2.126 - 2.201 0.665 - 261.5 1 2 0 0.0038 14 0 0 0 2.53E+06 1.81E+06 - - - 5.9312 0.9977 230117_WJC_METTL3_WT_vs_EV_F09.16488.16488.2 0.00138 22-Jun R.IYGLGSLALYEK[136.11].A sp|P36542|ATPG_HUMAN 1 1333.7373 1.67 67245 16488 2 1333.734126 667.8759 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6 3718.2 - 54201.6 - - - -2.3828 - 1.483 0.501 - 90.9 1 2 0 -0.0032 12 0 0 0 1.50E+06 8.99E+05 - - - 3.7772 0.9963 230117_WJC_METTL3_WT_vs_EV_F09.16495.16495.2 0.000947 14-May K.IPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1059.5502 1.27 67246 16495 2 1059.548207 530.7824 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3719.4 - 31688.8 - - - -1.848 - 1.24 0.399 - 126.7 1 2 0 -0.002 8 0 0 0 3.78E+07 2.98E+07 - - - 2.6362 0.993 230117_WJC_METTL3_WT_vs_EV_F09.16500.16500.2 0.00939 14-Jun K.IPDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1069.5584 1.26 67248 16500 2 1069.555557 535.7865 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3720.2 - 117415 - - - -2.6908 - 1.216 0.39 - 124.5 1 2 0 -0.0029 8 0 0 0 3.77E+07 2.98E+07 - - - 2.5105 0.9986 230117_WJC_METTL3_WT_vs_EV_F09.16536.16536.2 0.00804 20-Jun K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 38.33 67252 16536 2 1276.701791 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3726.5 - 22611.5 - - - -0.7143 - 1.564 0.369 - 162.4 1 2 0 -0.0009 11 0 0 0 8.06E+06 2.10E+05 - - - 2.9761 0.9993 230117_WJC_METTL3_WT_vs_EV_F09.16600.16600.2 0.00872 26-Apr K.FYGPAGPYGIFAGR[166.11].D sp|O15173|PGRC2_HUMAN 1 1481.7331 1.87 67265 16600 2 1481.733778 741.8738 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3737.1 - 33437.1 - - - 0.4542 - 1.033 0.521 - 46.9 1 2 0 0.0007 14 0 0 0 1.37E+06 7.31E+05 - - - 2.9704 0.9991 230117_WJC_METTL3_WT_vs_EV_F09.16610.16610.2 0.00629 16-Apr K.YDWDLLAAR.S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1121.5506 1.56 67267 16610 2 1121.550731 561.7826 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3738.7 - 26543 - - - 0.1534 - 0.862 0.57 - 59 1 2 0 0.0002 9 0 0 0 4.18E+05 2.68E+05 - - - 2.8213 0.9999 230117_WJC_METTL3_WT_vs_EV_F09.16652.16652.3 0.0233 Nov-76 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 2.03 67275 16652 3 2197.086259 733.3694 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3745.7 - 23674.7 - - - 0.0014 - 2.394 0.518 - 130.7 1 2 0 0 20 0 0 0 1.06E+07 5.21E+06 - - - 6.433 1 230117_WJC_METTL3_WT_vs_EV_F09.16668.16668.3 3.38E-05 14/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 2.03 67279 16668 3 2206.096161 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3748.3 - 14286.9 - - - 451.5463 - 3.138 0.633 - 224.3 1 2 0 0.9957 20 0 0 0 1.06E+07 5.21E+06 - - - 8.0959 0.9862 230117_WJC_METTL3_WT_vs_EV_F09.16689.16689.2 0.374 30-May R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 18.5 67284 16689 2 1549.879275 775.9487 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3751.7 - 17996.6 - - - -2.2692 - 1.283 0.264 - 66.8 1 2 0 -0.0035 16 0 0 0 3.60E+06 1.95E+05 - - - 1.6025 0.9985 230117_WJC_METTL3_WT_vs_EV_F09.16782.16782.2 7.17E-06 24-Jun K.ELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1702.7627 2.44 67315 16782 2 1702.759807 852.3886 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.14 3765.9 - 33186.1 - - - -1.7207 - 1.474 0.511 - 151 1 2 0 -0.0029 13 0 0 0 5.13E+05 2.11E+05 - - - 3.8101 0.995 230117_WJC_METTL3_WT_vs_EV_F09.16783.16783.2 0.0875 24-Apr K.ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1712.771 2.44 67316 16783 2 1712.769929 857.3928 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.14 3766.1 - 16529.5 - - - -0.6294 - 0.955 0.36 - 32.6 1 2 0 -0.0011 13 0 0 0 5.13E+05 2.11E+05 - - - 1.5814 0.9907 230117_WJC_METTL3_WT_vs_EV_F09.16785.16785.2 3.86 18-Apr R.FC[160.03]IWTESAFR.K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1315.6019 0.43 67318 16785 2 1315.599315 658.8082 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3766.3 - 15469.1 - - - -1.9976 - 1.116 0.332 - 64.2 1 2 0 -0.0026 10 0 0 0 2.10E+05 4.86E+05 - - - 1.7987 0.8686 230117_WJC_METTL3_WT_vs_EV_F09.16792.16792.2 2.42 18-Apr R.FC[160.03]IWTESAFR[166.11].K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1325.6102 0.43 67320 16792 2 1325.607426 663.8124 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.99 3767.4 - 29960.3 - - - -2.1024 - 0.922 0.135 - 70.3 1 2 0 -0.0028 10 0 0 0 2.10E+05 4.86E+05 - - - -0.1894 0.998 230117_WJC_METTL3_WT_vs_EV_F09.16820.16820.2 0.000647 24-Jul K.ILTFDQLALDSPK[136.11].G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1467.8064 0.69 67331 16820 2 1467.803679 734.9105 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3771.3 - 12691.9 - - - -1.8851 - 1.583 0.44 - 135.6 1 2 0 -0.0028 13 0 0 0 4.38E+05 6.33E+05 - - - 3.4688 0.997 230117_WJC_METTL3_WT_vs_EV_F09.16840.16840.2 0.00527 14-Apr R.GFC[160.03]FITFK[136.11].E "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1026.5088 1.04 67341 16840 2 1026.508647 514.2617 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.22 3774.1 - 23013.3 - - - -0.1724 - 0.868 0.43 - 60.3 1 2 0 -0.0002 8 0 0 0 8.30E+05 7.99E+05 - - - 1.79 0.9959 230117_WJC_METTL3_WT_vs_EV_F09.16866.16866.2 0.132 18-May K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.59 67352 16866 2 1176.719759 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3777.6 - 0 - - - -0.9909 - 1.389 0.272 - 58.1 1 2 0 -0.0012 10 0 0 0 1.29E+07 8.10E+06 - - - 1.9668 0.9979 230117_WJC_METTL3_WT_vs_EV_F09.16902.16902.3 0.000237 Sep-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 116 67366 16902 3 1603.759767 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3782.8 - 220466 - - - -2.602 - 1.431 0.42 - 78.6 1 2 0 -0.0042 12 0 0 0 4.82E+07 4.16E+05 - - - 4.2148 0.9705 230117_WJC_METTL3_WT_vs_EV_F09.17016.17016.2 0.0114 26-Apr R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 2.11 67392 17016 2 1487.770192 744.8959 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3800.7 - 70743.5 - - - -4.7541 - 1.067 0.424 - 50 1 2 0 -0.0071 14 0 0 0 1.28E+06 6.05E+05 - - - 2.3332 0.9984 230117_WJC_METTL3_WT_vs_EV_F09.17068.17068.2 0.000386 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 51.4 67406 17068 2 1603.760552 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3808.6 - 194244 - - - -2.1125 - 1.829 0.483 - 173.8 1 2 0 -0.0034 12 0 0 0 1.64E+08 3.20E+06 - - - 4.196 0.9993 230117_WJC_METTL3_WT_vs_EV_F09.17096.17096.3 0.000192 Aug-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 94.1 67412 17096 3 1603.759399 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3813.2 - 83695.7 - - - -2.8315 - 1.59 0.512 - 90.2 1 2 0 -0.0045 12 0 0 0 2.43E+07 2.58E+05 - - - 5.5324 0.9489 230117_WJC_METTL3_WT_vs_EV_F09.17134.17134.2 0.00875 20-Apr K.WYLENVYPELR.V sp|Q10471|GALT2_HUMAN 1 1480.7351 0.93 67425 17134 2 1480.726639 741.3748 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3818.9 - 0 - - - -5.6904 - 1.2 0.381 - 61.9 1 2 0 -0.0084 11 0 0 0 1.53E+06 1.64E+06 - - - 2.3456 0.9991 230117_WJC_METTL3_WT_vs_EV_F09.17146.17146.2 0.000667 22-Jun R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 51.05 67430 17146 2 1613.772144 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3820.5 - 32072.2 - - - -0.0409 - 1.462 0.406 - 102.4 1 2 0 -0.0001 12 0 0 0 1.75E+08 3.42E+06 - - - 3.039 0.986 230117_WJC_METTL3_WT_vs_EV_F09.17186.17186.2 0.00195 20-Jul K.WYLENVYPELR[166.11].V sp|Q10471|GALT2_HUMAN 1 1490.7433 0.92 67440 17186 2 1490.735642 746.3789 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3826.7 - 37094.9 - - - -5.1605 - 1.653 0.44 - 183.7 1 2 0 -0.0077 11 0 0 0 1.54E+06 1.67E+06 - - - 3.6481 0.995 230117_WJC_METTL3_WT_vs_EV_F09.17195.17195.2 0.00455 28-Jul K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 6.46 67444 17195 2 1658.903538 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3828 - 72233.6 - - - -3.3329 - 1.718 0.422 - 121.8 1 2 0 -0.0055 15 0 0 0 3.28E+06 5.08E+05 - - - 3.4866 0.8571 230117_WJC_METTL3_WT_vs_EV_F09.17204.17204.3 0.000408 Jul-76 W.ITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 2158.1746 2.15 67449 17204 3 2158.171308 720.3988 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3829.2 - 9816.12 - - - -1.5332 - 1.654 0.477 - 38.8 1 1 0 -0.0033 20 0 0 0 4.76E+06 2.21E+06 - - - 5.0779 0.9896 230117_WJC_METTL3_WT_vs_EV_F09.17210.17210.2 0.0106 16-Jun R.GFAFVYFER[166.11].L sp|Q13595|TRA2A_HUMAN 1 1144.5581 0.86 67452 17210 2 1144.555248 573.2863 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3830.1 - 38958.5 - - - -2.4927 - 1.234 0.316 - 158.7 1 2 0 -0.0029 9 0 0 0 1.12E+06 1.31E+06 - - - 1.9824 0.9995 230117_WJC_METTL3_WT_vs_EV_F09.17212.17212.2 3.07E-06 28-Sep K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 6.46 67454 17212 2 1666.92282 834.4689 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3830.4 - 20121.9 - - - -0.2682 - 2.244 0.417 - 281.8 1 2 0 -0.0004 15 0 0 0 3.28E+06 5.08E+05 - - - 4.108 0.9576 230117_WJC_METTL3_WT_vs_EV_F09.17236.17236.2 0.0441 26-Apr K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.58 67469 17236 2 1416.839539 709.4289 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3833.6 - 0 - - - -2.5599 - 0.987 0.248 - 33.3 1 2 0 -0.0036 14 0 0 0 5.49E+05 3.48E+05 - - - 0.8388 0.867 230117_WJC_METTL3_WT_vs_EV_F09.17267.17267.2 0.95 24-Mar K.VLGTAFDPFLGGK.N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1320.7078 10.77 67483 17267 2 1320.704878 661.3612 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3838 - 22182.2 - - - -2.2034 - 0.6 0.286 - 27.4 1 2 0 -0.0029 13 0 0 0 2.37E+06 2.20E+05 - - - -0.1586 1 230117_WJC_METTL3_WT_vs_EV_F09.17275.17275.2 0.000164 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 52.69 67487 17275 2 1603.758487 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3839.1 - 1.99E+06 - - - -3.4001 - 1.922 0.522 - 227.4 1 2 0 -0.0055 12 0 0 0 1.74E+08 3.31E+06 - - - 4.6139 0.9998 230117_WJC_METTL3_WT_vs_EV_F09.17304.17304.3 0.000123 Aug-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 136.12 67495 17304 3 1603.762817 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3843.4 - 152354 - - - -0.7002 - 1.587 0.497 - 76.8 1 2 0 -0.0011 12 0 0 0 2.14E+07 1.57E+05 - - - 5.3609 1 230117_WJC_METTL3_WT_vs_EV_F09.17316.17316.2 1.30E-06 26-Sep R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.95 67498 17316 2 1669.891537 835.9552 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3845.2 - 64781.8 - - - -2.6307 - 2.083 0.606 - 267 1 2 0 -0.0044 14 0 0 0 4.14E+06 4.34E+06 - - - 5.357 0.9975 230117_WJC_METTL3_WT_vs_EV_F09.17318.17318.2 5.08E-05 26-Jun R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.95 67499 17318 2 1661.877254 831.9481 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3845.4 - 89288.2 - - - -2.6933 - 1.567 0.525 - 115.3 1 2 0 -0.0045 14 0 0 0 4.14E+06 4.34E+06 - - - 4.0444 0.9308 230117_WJC_METTL3_WT_vs_EV_F09.17359.17359.2 0.114 22-May R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 71.81 67516 17359 2 1613.76728 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3851.3 - 11725.5 - - - -3.055 - 1.116 0.184 - 63.5 1 2 0 -0.0049 12 0 0 0 1.57E+08 2.19E+06 - - - 0.6872 0.9823 230117_WJC_METTL3_WT_vs_EV_F09.17401.17401.2 0.00687 26-May K.LVINGNPITIFQER.D sp|P04406|G3P_HUMAN 1 1612.8937 1.98 67519 17401 2 1612.88857 807.4541 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3858.5 - 35851 - - - -3.175 - 1.186 0.327 - 62.6 1 2 0 -0.0051 14 0 0 0 1.89E+06 9.54E+05 - - - 1.8827 0.9738 230117_WJC_METTL3_WT_vs_EV_F09.17445.17445.2 0.107 28-Apr R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 4.66 67536 17445 2 1700.897705 851.4565 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3865.5 - 0 - - - -0.4686 - 0.905 0.198 - 39.9 1 2 0 -0.0008 15 0 0 0 3.43E+06 7.37E+05 - - - 0.2578 0.9861 230117_WJC_METTL3_WT_vs_EV_F09.17450.17450.2 0.00093 26-May K.LFIYNPTTGEFLGR.T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1626.8406 2.11 67538 17450 2 1626.834126 814.4276 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3866.2 - 0 - - - -3.9752 - 1.465 0.358 - 68.4 1 2 0 -0.0065 14 0 0 0 9.65E+05 4.58E+05 - - - 2.6414 0.9992 230117_WJC_METTL3_WT_vs_EV_F09.17455.17455.3 7.39E-07 Aug-56 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 5.73 67540 17455 3 1700.893337 567.9734 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3866.9 - 181898 - - - -3.0366 - 1.914 0.489 - 98.6 1 2 0 -0.0052 15 0 0 0 8.68E+05 1.51E+05 - - - 5.6844 0.9784 230117_WJC_METTL3_WT_vs_EV_F09.17456.17456.2 0.0431 28-Apr R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 4.66 67541 17456 2 1710.899677 856.4607 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3867.1 - 276787 - - - -4.1469 - 1.194 0.379 - 34.2 1 2 0 -0.0071 15 0 0 0 3.43E+06 7.37E+05 - - - 2.274 0.9987 230117_WJC_METTL3_WT_vs_EV_F09.17476.17476.2 1.80E-05 22-Oct R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 324.8 67556 17476 2 1603.760883 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3869.7 - 640938 - - - -1.9061 - 1.853 0.507 - 297.3 1 2 0 -0.0031 12 0 0 0 5.27E+07 1.62E+05 - - - 4.4077 0.9858 230117_WJC_METTL3_WT_vs_EV_F09.17484.17484.3 0.000432 May-56 R.HFYWYLTNEGIQYLR[166.11].D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2011.982 1.7 67559 17484 3 2011.973581 671.6679 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3870.9 - 9441.27 - - - -4.1859 - 1.212 0.391 - 32 1 2 0 -0.0084 15 0 0 0 3.10E+06 1.83E+06 - - - 3.3986 0.9326 230117_WJC_METTL3_WT_vs_EV_F09.17494.17494.2 6.7 18-Feb K.FLLFGIQDGK.R "sp|P22105|TENX_HUMAN,tr|A0A140TA52|A0A140TA52_HUMAN,tr|A0A140T956|A0A140T956_HUMAN,tr|A0A140TA33|A0A140TA33_HUMAN,tr|A0A140T8Y3|A0A140T8Y3_HUMAN,tr|A0A3B3ISX9|A0A3B3ISX9_HUMAN,tr|A0A140T9C0|A0A140T9C0_HUMAN,tr|A0A140T902|A0A140T902_HUMAN,tr|A0A140T8Z8|A0A140T8Z8_HUMAN,tr|A0A140TA41|A0A140TA41_HUMAN" 10 1136.623 999 67561 17494 2 1136.623397 569.3188 Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB PE=1 SV=5 5.84 3872.5 - 88689.9 - - - 0.3528 - 0.813 0.148 - 12.8 3 2 0 0.0004 10 0 0 0 1.75E+06 0.00E+00 - - - -0.657 0.9998 230117_WJC_METTL3_WT_vs_EV_F09.17497.17497.3 3.20E-07 Aug-56 R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 1.7 67562 17497 3 2001.969602 668.3319 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3872.9 - 23144.1 - - - -2.0635 - 1.829 0.625 - 86.9 1 2 0 -0.0041 15 0 0 0 3.13E+06 1.84E+06 - - - 7.0824 0.9989 230117_WJC_METTL3_WT_vs_EV_F09.17503.17503.3 0.00378 Jun-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 450.32 67564 17503 3 1603.761175 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3873.9 - 242966 - - - -1.7241 - 1.443 0.427 - 41.6 1 2 0 -0.0028 12 0 0 0 8.43E+06 1.87E+04 - - - 4.3164 1 230117_WJC_METTL3_WT_vs_EV_F09.17553.17553.2 4.20E-06 26-Nov K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.43 67580 17553 2 1672.877802 837.4479 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3881.4 - 26735.8 - - - -2.0468 - 2.585 0.601 - 519.3 1 2 0 -0.0034 14 0 0 0 1.13E+06 2.61E+06 - - - 5.8622 0.9983 230117_WJC_METTL3_WT_vs_EV_F09.17554.17554.3 0.00201 May-52 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 0.4 67581 17554 3 1672.878392 558.6344 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3881.5 - 26126.9 - - - -1.6941 - 1.116 0.456 - 45.3 1 2 0 -0.0028 14 0 0 0 6.15E+05 1.55E+06 - - - 3.9148 1 230117_WJC_METTL3_WT_vs_EV_F09.17555.17555.2 1.47E-06 26-Nov K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 0.43 67582 17555 2 1662.871261 832.4438 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3881.7 - 14893.6 - - - -1.0193 - 2.615 0.532 - 433.5 1 2 0 -0.0017 14 0 0 0 1.13E+06 2.61E+06 - - - 5.3821 1 230117_WJC_METTL3_WT_vs_EV_F09.17580.17580.2 5.18E-06 26-Oct K.LFSLELVDESGEIR[166.11].A sp|P27694|RFA1_HUMAN 1 1615.8333 0.13 67595 17580 2 1615.832115 808.9239 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4 3885.2 - 45395.5 - - - -0.7167 - 2.222 0.492 - 415.7 1 2 0 -0.0012 14 0 0 0 7.86E+04 6.11E+05 - - - 4.6781 0.9968 230117_WJC_METTL3_WT_vs_EV_F09.17582.17582.2 0.00234 26-Jun K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.84 67596 17582 2 1651.926906 826.9731 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3885.6 - 65824.9 - - - -2.87 - 1.424 0.518 - 100.3 1 2 0 -0.0047 14 0 0 0 1.77E+06 2.12E+06 - - - 3.7525 0.9993 230117_WJC_METTL3_WT_vs_EV_F09.17584.17584.3 0.00132 Jul-68 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.84 67597 17584 3 1936.009274 646.3445 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3885.8 - 37053.6 - - - -1.1958 - 1.294 0.473 - 59 1 2 0 -0.0023 18 0 0 0 7.37E+05 8.76E+05 - - - 4.4546 0.9837 230117_WJC_METTL3_WT_vs_EV_F09.17591.17591.2 0.00411 May-34 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 0.97 67600 17591 2 1936.003774 969.0131 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3886.8 - 18191.5 - - - -4.0366 - 1.183 0.413 - 83.8 1 2 0 -0.0078 18 0 0 0 8.11E+05 8.38E+05 - - - 2.5021 0.9728 230117_WJC_METTL3_WT_vs_EV_F09.17649.17649.2 0.277 18-Apr K.LLEPVLLLGK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1093.7111 1.64 67628 17649 2 1093.711179 547.8628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3895.2 - 7348.41 - - - 0.0878 - 0.787 0.223 - 43.7 1 2 0 0.0001 10 0 0 0 3.08E+06 1.87E+06 - - - 0.0195 0.9991 230117_WJC_METTL3_WT_vs_EV_F09.17684.17684.2 0.00174 22-Jul R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 118.8 67641 17684 2 1603.763558 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3900.2 - 112430 - - - -0.2382 - 1.369 0.438 - 117.9 1 2 0 -0.0004 12 0 0 0 6.41E+07 5.39E+05 - - - 3.1023 0.9503 230117_WJC_METTL3_WT_vs_EV_F09.17737.17737.2 1.23 22-Apr K.IILDLISESPIK.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1339.7963 1.23 67653 17737 2 1339.793176 670.9054 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3909.2 - 8771.73 - - - -2.3086 - 0.959 0.227 - 39.5 1 2 0 -0.0031 12 0 0 0 2.12E+06 1.72E+06 - - - 0.6065 0.995 230117_WJC_METTL3_WT_vs_EV_F09.17740.17740.2 0.000295 26-May K.FGGDFLVYPGDPLR.F "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN" 4 1551.7722 10.65 67654 17740 2 1551.766792 776.8934 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.21 3909.6 - 18948.7 - - - -3.4715 - 1.184 0.564 - 57 1 2 0 -0.0054 14 0 0 0 4.59E+05 4.31E+04 - - - 3.6289 0.9974 230117_WJC_METTL3_WT_vs_EV_F09.17742.17742.2 0.0384 22-Jun K.IILDLISESPIK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1347.8105 1.23 67655 17742 2 1347.808775 674.9125 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3909.9 - 15125.6 - - - -1.2569 - 1.487 0.341 - 92.6 1 2 0 -0.0017 12 0 0 0 2.12E+06 1.72E+06 - - - 2.603 1 230117_WJC_METTL3_WT_vs_EV_F09.17769.17769.2 1.46E-05 24-Aug R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.14 67663 17769 2 1438.782191 720.3983 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3914.1 - 28838 - - - 0.1216 - 1.9 0.531 - 261.7 1 2 0 0.0002 13 0 0 0 1.44E+06 1.27E+06 - - - 4.6102 0.9792 230117_WJC_METTL3_WT_vs_EV_F09.17779.17779.2 0.0448 16-Mar R.FWYFVSQLK.K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1216.6281 0.71 67665 17779 2 1216.625618 609.3213 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3915.7 - 86829.8 - - - -2.0244 - 0.909 0.321 - 21.9 1 2 0 -0.0025 9 0 0 0 2.35E+06 3.30E+06 - - - 1.1351 0.9985 230117_WJC_METTL3_WT_vs_EV_F09.17790.17790.3 0.00698 May-84 K.EKPYFPIPEEYTFIQNVPLEDR.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2723.3483 2.29 67667 17790 3 2723.339328 908.79 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3917.4 - 25707.2 - - - -3.2886 - 1.496 0.5 - 19.5 1 2 0 -0.009 22 0 0 0 1.36E+06 5.96E+05 - - - 5.067 0.9995 230117_WJC_METTL3_WT_vs_EV_F09.17825.17825.2 0.00183 22-Aug K.WLAPDGLIFPDR[166.11].A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1408.7379 0.81 67676 17825 2 1408.737335 705.3762 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3922.7 - 8290.28 - - - -0.3698 - 1.818 0.494 - 204.9 1 2 0 -0.0005 12 0 0 0 1.63E+06 2.01E+06 - - - 4.2623 0.9984 230117_WJC_METTL3_WT_vs_EV_F09.17831.17831.2 0.00458 26-Aug R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.14 67679 17831 2 1478.89271 740.4549 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3923.5 - 28453.1 - - - -1.6844 - 1.673 0.455 - 126.8 1 2 0 -0.0025 14 0 0 0 7.56E+05 6.65E+05 - - - 3.6923 0.9969 230117_WJC_METTL3_WT_vs_EV_F09.17833.17833.2 0.000136 22-Aug K.WLAPDGLIFPDR.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1398.7296 0.81 67680 17833 2 1398.725623 700.3721 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3923.8 - 79219.7 - - - -2.8333 - 1.983 0.399 - 188.7 1 2 0 -0.004 12 0 0 0 1.63E+06 2.01E+06 - - - 3.7881 0.998 230117_WJC_METTL3_WT_vs_EV_F09.17839.17839.2 0.000312 30-Apr K.LFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1783.8992 1.22 67683 17839 2 1783.896468 892.9569 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3924.6 - 112070 - - - -1.5483 - 1.221 0.497 - 37.3 1 2 0 -0.0028 16 0 0 0 6.24E+05 5.10E+05 - - - 3.2019 1 230117_WJC_METTL3_WT_vs_EV_F09.17840.17840.2 2.87E-06 30-Jul K.LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1793.9075 1.22 67684 17840 2 1793.9061 897.961 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3924.7 - 96959.1 - - - -0.7804 - 1.805 0.568 - 123.6 1 2 0 -0.0014 16 0 0 0 6.24E+05 5.10E+05 - - - 4.6877 0.966 230117_WJC_METTL3_WT_vs_EV_F09.17863.17863.2 0.0782 20-May R.LFEFAGYDVLR[166.11].L sp|P54136|SYRC_HUMAN 1 1338.6848 1.12 67697 17863 2 1338.682815 670.3497 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3927.6 - 62856.7 - - - -1.4514 - 1.353 0.105 - 81.1 2 2 0 -0.0019 11 0 0 0 6.28E+05 5.60E+05 - - - 0.4993 0.9985 230117_WJC_METTL3_WT_vs_EV_F09.17877.17877.2 0.0068 20-Jun R.LFEFAGYDVLR.L sp|P54136|SYRC_HUMAN 1 1328.6765 1.22 67703 17877 2 1328.674681 665.3455 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3929.5 - 10835.9 - - - -1.36 - 1.49 0.45 - 141.2 1 2 0 -0.0018 11 0 0 0 6.28E+05 5.16E+05 - - - 3.4429 0.9965 230117_WJC_METTL3_WT_vs_EV_F09.17885.17885.2 0.000285 22-Jul R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 999 67705 17885 2 1603.761545 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3931 - 56114 - - - -1.4934 - 1.348 0.355 - 146.5 1 2 0 -0.0024 12 0 0 0 2.83E+06 0.00E+00 - - - 2.448 0.9822 230117_WJC_METTL3_WT_vs_EV_F09.17909.17909.2 0.0832 22-Mar R.FSTFFDDAPVFR.L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1447.6772 3.5 67717 17909 2 1447.676215 724.8459 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3934.1 - 14029.3 - - - -0.6915 - 0.795 0.296 - 27.2 1 2 0 -0.001 12 0 0 0 3.98E+05 1.14E+05 - - - 0.6233 1 230117_WJC_METTL3_WT_vs_EV_F09.17923.17923.2 3.46E-07 30-Jul K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 0.91 67722 17923 2 1807.919373 904.9689 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3936.2 - 28675.9 - - - -2.0891 - 1.747 0.604 - 141.7 1 2 0 -0.0038 16 0 0 0 2.44E+06 2.68E+06 - - - 4.8726 0.9987 230117_WJC_METTL3_WT_vs_EV_F09.17926.17926.2 5.90E-07 30-Sep K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 0.91 67723 17926 2 1797.911403 899.9647 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3936.6 - 52508 - - - -1.9339 - 2.012 0.497 - 168.6 1 2 0 -0.0035 16 0 0 0 2.44E+06 2.68E+06 - - - 4.4296 0.998 230117_WJC_METTL3_WT_vs_EV_F09.17936.17936.3 0.0177 Apr-60 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 1.42 67728 17936 3 1807.921043 603.6483 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3938 - 51117.1 - - - -1.1654 - 1.07 0.424 - 24.1 1 2 0 -0.0021 16 0 0 0 3.58E+05 2.51E+05 - - - 3.4402 0.998 230117_WJC_METTL3_WT_vs_EV_F09.17944.17944.2 0.216 30-Apr R.ELFEQYGAVYEINVLR.D "sp|Q92879|CELF1_HUMAN,tr|F5H4Y5|F5H4Y5_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PSH0|E9PSH0_HUMAN,tr|E9PQK4|E9PQK4_HUMAN,tr|E9PKA1|E9PKA1_HUMAN,tr|E9PKU1|E9PKU1_HUMAN,tr|F5H0D8|F5H0D8_HUMAN" 8 1941.9836 -1 67736 17944 2 1941.985199 971.9991 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 4.25 3939 - 20529.8 - - - 0.8085 - 1.113 0.336 - 45.9 1 2 0 0.0016 16 0 0 0 0.00E+00 0.00E+00 - - - 1.7854 0.9979 230117_WJC_METTL3_WT_vs_EV_F09.17949.17949.2 0.000266 14-Aug R.GFGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 913.5062 1.17 67738 17949 2 913.504249 457.7604 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3939.7 - 727044 - - - -2.1084 - 1.51 0.457 - 210.4 1 2 0 -0.0019 8 0 0 0 2.36E+06 2.02E+06 - - - 3.6587 0.9974 230117_WJC_METTL3_WT_vs_EV_F09.17950.17950.2 0.00436 14-Jul R.GFGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 921.5204 1.17 67739 17950 2 921.518316 461.7675 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3939.8 - 636641 - - - -2.2344 - 1.355 0.468 - 141.6 1 2 0 -0.0021 8 0 0 0 2.36E+06 2.02E+06 - - - 3.4133 1 230117_WJC_METTL3_WT_vs_EV_F09.17951.17951.2 4.61E-06 22-Dec K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 999 67740 17951 2 1459.790157 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3939.9 - 520524 - - - -1.431 - 2.697 0.507 - 693 1 2 0 -0.0021 12 0 0 0 2.04E+06 0.00E+00 - - - 5.3955 0.9994 230117_WJC_METTL3_WT_vs_EV_F09.17996.17996.2 0.000224 28-Jul K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 9.25 67758 17996 2 1591.944789 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3946.7 - 33901.4 - - - -0.1319 - 1.706 0.467 - 100.8 1 2 0 -0.0002 15 0 0 0 3.00E+06 3.24E+05 - - - 3.8034 0.9963 230117_WJC_METTL3_WT_vs_EV_F09.18017.18017.2 0.00147 20-Jun K.ILDVEIIFNER[166.11].G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1369.7481 1.29 67766 18017 2 1369.744622 685.8813 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3949.9 - 24264.2 - - - -2.5297 - 1.486 0.415 - 157.8 1 2 0 -0.0035 11 0 0 0 1.59E+06 1.23E+06 - - - 3.1766 0.9977 230117_WJC_METTL3_WT_vs_EV_F09.18062.18062.2 0.154 20-Apr K.DVLLPWYNAYR.F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1408.7139 1.79 67781 18062 2 1408.714554 705.3642 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3957 - 21095.5 - - - 0.4387 - 1.109 0.33 - 54.4 1 2 0 0.0006 11 0 0 0 3.62E+05 2.02E+05 - - - 1.7581 1 230117_WJC_METTL3_WT_vs_EV_F09.18073.18073.2 6.65E-06 26-Sep K.VVIGMDVAASEFFR.S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1539.7756 2.81 67786 18073 2 1539.771669 770.8951 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.37 3958.6 - 37983.1 - - - -2.5205 - 2.02 0.584 - 292.2 1 2 0 -0.0039 14 0 0 0 6.05E+05 2.15E+05 - - - 5.1176 1 230117_WJC_METTL3_WT_vs_EV_F09.18078.18078.2 1.33E-08 Jun-34 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 18.67 67789 18078 2 1911.947626 956.9806 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3959.2 - 48903.3 - - - 0.5497 - 2.158 0.605 - 78.6 1 2 0 0.0011 18 0 0 0 6.97E+05 3.73E+04 - - - 5.4003 1 230117_WJC_METTL3_WT_vs_EV_F09.18091.18091.4 1.42E-06 10/162 R.PHNVQPNWITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 3130.6312 2.84 67796 18091 4 3130.624113 783.6651 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.14 3961 - 50034.5 - - - -2.2689 - 2.503 0.631 - 39.5 1 1 0 -0.0071 28 0 0 0 2.68E+06 9.41E+05 - - - 5.0011 0.9985 230117_WJC_METTL3_WT_vs_EV_F09.18128.18128.2 7.24E-06 28-Jun R.LGLEFFDQPAVPLAR.A "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1671.8984 1.02 67811 18128 2 1671.89488 836.9565 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 4.37 3966 - 21576.4 - - - -2.1305 - 1.481 0.586 - 105.1 1 2 0 -0.0036 15 0 0 0 1.62E+05 1.58E+05 - - - 4.3336 1 230117_WJC_METTL3_WT_vs_EV_F09.18133.18133.4 1.11E-14 22/198 K.IELFGRPHNVQPNWITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 3846.0329 4.24 67813 18133 4 3846.023505 962.5155 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.26 3966.6 - 153555 - - - -2.4495 - 4.454 0.662 - 157.6 1 2 0 -0.0094 34 0 0 0 1.77E+06 4.17E+05 - - - 5.4309 0.9982 230117_WJC_METTL3_WT_vs_EV_F09.18153.18153.2 0.000518 26-May M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 2.44 67822 18153 2 1676.895544 839.4565 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3969.4 - 54676.8 - - - -1.764 - 1.435 0.481 - 61.1 1 2 0 -0.003 14 0 0 0 5.42E+05 2.22E+05 - - - 3.4991 0.9978 230117_WJC_METTL3_WT_vs_EV_F09.18154.18154.2 5.44E-05 26-Jun M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 2.44 67823 18154 2 1686.902227 844.4607 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3969.5 - 16800 - - - -2.6943 - 1.477 0.577 - 109.1 1 2 0 -0.0045 14 0 0 0 5.42E+05 2.22E+05 - - - 4.28 0.9999 230117_WJC_METTL3_WT_vs_EV_F09.18224.18224.3 8.13E-06 Aug-84 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.39 67856 18224 3 2364.324111 789.1161 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3979.2 - 53117.6 - - - -0.9796 - 1.908 0.561 - 60.5 1 2 0 -0.0023 22 0 0 0 2.16E+06 1.55E+06 - - - 6.3256 1 230117_WJC_METTL3_WT_vs_EV_F09.18238.18238.3 8.48E-10 15/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.4 67863 18238 3 2382.344713 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3981.2 - 81107.1 - - - -1.7562 - 3.002 0.665 - 240.7 1 2 0 -0.0042 22 0 0 0 2.17E+06 1.55E+06 - - - 8.5591 0.9589 230117_WJC_METTL3_WT_vs_EV_F09.18248.18248.2 0.115 22-Apr K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 1.07 67868 18248 2 1336.845854 669.4314 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3982.6 - 54503.7 - - - -1.7885 - 1.114 0.179 - 64.7 2 2 0 -0.0024 12 0 0 0 1.12E+06 1.05E+06 - - - 0.5119 0.9848 230117_WJC_METTL3_WT_vs_EV_F09.18249.18249.2 0.492 22-May K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 1.07 67869 18249 2 1344.85907 673.4385 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3982.8 - 39729.9 - - - -2.5096 - 1.238 0.277 - 88.1 1 2 0 -0.0034 12 0 0 0 1.12E+06 1.05E+06 - - - 1.6476 0.9944 230117_WJC_METTL3_WT_vs_EV_F09.18281.18281.2 0.0258 22-Apr K.TSDLIVLGLPWK.T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1340.7704 2.65 67875 18281 2 1340.767862 671.3925 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3987.8 - 32004 - - - -1.884 - 1.088 0.401 - 46.4 1 2 0 -0.0025 12 0 0 0 4.62E+05 1.74E+05 - - - 2.2239 0.9801 230117_WJC_METTL3_WT_vs_EV_F09.18309.18309.3 0.000207 Aug-44 K.LR[166.11]EC[160.03]LPLIIFLR[166.11].N sp|P62701|RS4X_HUMAN 1 1561.9281 1.3 67884 18309 3 1561.926694 521.65 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3992.1 - 83609.8 - - - -0.9194 - 1.847 0.454 - 116.9 1 2 1 -0.0014 12 0 0 0 3.44E+06 2.64E+06 - - - 5.302 0.9999 230117_WJC_METTL3_WT_vs_EV_F09.18317.18317.3 6.66E-05 Sep-60 K.IFEIFGPVAHPFYVLR.F sp|Q96HR8|NAF1_HUMAN 1 1904.0349 1.8 67887 18317 3 1904.036959 635.6856 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 6.75 3993.3 - 43755.8 - - - 1.094 - 2.205 0.52 - 90.6 1 2 0 0.0021 16 0 0 0 9.04E+05 5.01E+05 - - - 6.3658 0.9999 230117_WJC_METTL3_WT_vs_EV_F09.18320.18320.3 3.01E-07 Jul-60 K.IFEIFGPVAHPFYVLR[166.11].F sp|Q96HR8|NAF1_HUMAN 1 1914.0431 1.8 67889 18320 3 1914.043807 639.0217 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 6.75 3993.6 - 41309.7 - - - 0.3453 - 2.039 0.551 - 58.3 1 2 0 0.0007 16 0 0 0 9.04E+05 5.01E+05 - - - 6.511 0.9794 230117_WJC_METTL3_WT_vs_EV_F09.18326.18326.2 0.027 20-Apr K.FVDILTNWYVR.M "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1424.7452 0.02 67890 18326 2 1424.741184 713.3799 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.84 3994.6 - 9137.66 - - - -2.844 - 0.97 0.353 - 56.8 1 2 0 -0.0041 11 0 0 0 1.78E+05 7.70E+06 - - - 1.5646 0.9999 230117_WJC_METTL3_WT_vs_EV_F09.18333.18333.3 1.65E-06 Sep-52 R.HPYFYAPELLFFAK.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 1741.8868 999 67894 18333 3 1741.886543 581.6362 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6.75 3995.6 - 48603.6 - - - -0.1562 - 1.918 0.597 - 94 1 2 0 -0.0003 14 0 0 0 7.64E+05 0.00E+00 - - - 6.9267 0.9978 230117_WJC_METTL3_WT_vs_EV_F09.18336.18336.2 0.0158 26-May K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 999 67897 18336 2 1537.767981 769.8922 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3996 - 31356 - - - -1.1803 - 1.442 0.379 - 69.3 1 2 0 -0.0018 14 0 0 0 3.01E+05 0.00E+00 - - - 2.7583 1 230117_WJC_METTL3_WT_vs_EV_F09.18342.18342.2 1.03E-06 18-Aug R.C[160.03]WAGSLWLFK[136.11].D sp|Q9BQA1|MEP50_HUMAN 1 1274.6362 0.48 67901 18342 2 1274.634351 638.3254 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 3996.8 - 205150 - - - -1.4114 - 1.974 0.538 - 206 1 2 0 -0.0018 10 0 0 0 3.13E+06 6.48E+06 - - - 4.9124 0.9989 230117_WJC_METTL3_WT_vs_EV_F09.18343.18343.2 1.63E-05 18-Jul R.C[160.03]WAGSLWLFK.D sp|Q9BQA1|MEP50_HUMAN 1 1266.6219 0.48 67902 18343 2 1266.620009 634.3183 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 3996.9 - 71498.8 - - - -1.5324 - 1.661 0.514 - 146.5 1 2 0 -0.0019 10 0 0 0 3.13E+06 6.48E+06 - - - 4.2532 0.9849 230117_WJC_METTL3_WT_vs_EV_F09.18346.18346.2 0.0156 16-May K.LLLPWLEAR.L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1109.6597 9.78 67903 18346 2 1109.655923 555.8371 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6 3997.3 - 46215.8 - - - -3.4182 - 1.168 0.364 - 110.4 1 2 0 -0.0038 9 0 0 0 2.64E+07 2.70E+06 - - - 2.1776 0.9936 230117_WJC_METTL3_WT_vs_EV_F09.18352.18352.2 0.124 30-Apr K.AAGVNVEPFWPGLFAK[136.11].A sp|P05386|RLA1_HUMAN 1 1709.9021 1.56 67907 18352 2 1709.904589 855.9583 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3998.1 - 30340.2 - - - 1.4685 - 0.943 0.256 - 39.4 1 2 0 0.0025 16 0 0 0 5.39E+05 3.44E+05 - - - 0.7867 1 230117_WJC_METTL3_WT_vs_EV_F09.18364.18364.2 0.102 28-Nov R.QVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1581.909 -1 67914 18364 2 1581.903635 791.9618 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 3999.5 - 1.76E+07 - - - -3.3959 - 2.516 0.522 - 429.9 1 2 0 -0.0054 15 0 0 0 0.00E+00 0.00E+00 - - - 5.1632 1 230117_WJC_METTL3_WT_vs_EV_F09.18365.18365.2 3.85E-07 26-Nov R.RLNIPVLQDDGFLF.L sp|Q86U44|MTA70_HUMAN 1 1645.8828 -1 67915 18365 2 1645.877271 823.9487 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 3999.6 - 6.33E+07 - - - -3.3544 - 2.182 0.546 - 302.3 1 1 0 -0.0055 14 0 0 0 0.00E+00 0.00E+00 - - - 5.03 0.9865 230117_WJC_METTL3_WT_vs_EV_F09.18366.18366.2 2.18 16-Jul R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.3 67916 18366 2 1108.649378 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 3999.6 - 3.82E+07 - - - -3.4772 - 1.554 0.273 - 105.4 1 2 0 -0.0039 9 0 0 0 4.91E+07 3.78E+07 - - - 2.3315 0.9904 230117_WJC_METTL3_WT_vs_EV_F10.02366.02366.2 5.48 12-May K.YDSTHGR.Y "sp|O14556|G3PT_HUMAN,tr|K7EP73|K7EP73_HUMAN" 2 834.362 -1 67979 2366 2 834.361434 418.1883 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 6.74 1181.8 - 265001 - - - -0.7143 - 1.174 0.228 - 84.5 2 2 0 -0.0006 7 0 0 0 0.00E+00 0.00E+00 - - - 1.0986 0.9669 230117_WJC_METTL3_WT_vs_EV_F10.10689.10689.2 1.10E-05 Jun-32 N.IVSNASC[160.03]TTNC[160.03]LAPLAK.V "sp|O14556|G3PT_HUMAN,tr|K7EP73|K7EP73_HUMAN" 2 1818.8968 999 68117 10689 2 1818.897256 910.4557 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 8.06 2747.3 - 35815.7 - - - 0.248 - 1.426 0.541 - 68.4 1 1 0 0.0005 17 0 0 0 1.72E+06 0.00E+00 - - - 3.9092 0.9998 230117_WJC_METTL3_WT_vs_EV_F10.10726.10726.3 0.00253 Jun-68 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 2.41 68118 10726 3 2070.864443 691.296 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2754.2 - 10981 - - - -0.8929 - 1.249 0.571 - 35.1 1 2 0 -0.0019 18 0 0 0 1.78E+06 7.36E+05 - - - 5.4592 0.9327 230117_WJC_METTL3_WT_vs_EV_F10.10739.10739.3 1.40E-06 Jul-68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 2.4 68119 10739 3 2079.873534 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2756.6 - 19440.8 - - - 477.6811 - 1.475 0.68 - 48.9 1 2 0 0.993 18 0 0 0 1.77E+06 7.36E+05 - - - 6.814 0.8546 230117_WJC_METTL3_WT_vs_EV_F10.10937.10937.2 6.29 24-Apr R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 68125 10937 2 1302.607984 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2793.3 - 21361.7 - - - -0.9304 - 0.82 0.1 - 24.3 1 2 0 -0.0012 13 0 0 0 8.45E+06 0.00E+00 - - - -0.7301 0.9963 230117_WJC_METTL3_WT_vs_EV_F10.10978.10978.2 0.00777 20-Apr R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 3.56 68129 10978 2 1201.607171 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2800.5 - 31113.5 - - - -1.6361 - 1.064 0.444 - 60 1 2 0 -0.002 11 0 0 0 4.78E+06 1.35E+06 - - - 2.4876 0.9994 230117_WJC_METTL3_WT_vs_EV_F10.11349.11349.4 0.00218 8/108 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 1.7 68150 11349 4 2080.021874 521.0129 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2867 - 130939 - - - -0.3168 - 1.403 0.449 - 29.3 1 2 0 -0.0007 19 0 0 0 6.16E+06 3.62E+06 - - - 3.2485 0.9037 230117_WJC_METTL3_WT_vs_EV_F10.12412.12412.3 0.102 Mar-52 R.SDSFENPVLQQHFR[166.11].N "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1712.8146 1.08 68214 12412 3 1712.811426 571.9455 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.3 3056.8 - 14107.2 - - - -1.8548 - 0.683 0.307 - 12.5 1 2 0 -0.0032 14 0 0 0 1.08E+06 1.00E+06 - - - 0.9486 0.9753 230117_WJC_METTL3_WT_vs_EV_F10.12488.12488.2 0.325 16-May K.VSISFENYR.K "sp|O14730|RIOK3_HUMAN,tr|B4E1Q4|B4E1Q4_HUMAN" 2 1113.5455 246.37 68224 12488 2 1113.542984 557.78 Serine\threonine-protein kinase RIO3 OS=Homo sapiens OX=9606 GN=RIOK3 PE=1 SV=2 5.97 3069.8 - 23351.2 - - - -2.2361 - 1.207 0.206 - 92 1 2 0 -0.0025 9 0 0 0 4.45E+06 1.80E+04 - - - 1.106 0.8944 230117_WJC_METTL3_WT_vs_EV_F10.12940.12940.2 4.3 20-Apr R.VSDHASAMNKR.L "sp|Q8NBW4|S38A9_HUMAN,tr|D6R9Q7|D6R9Q7_HUMAN,tr|D6R9X0|D6R9X0_HUMAN,tr|E7ESU6|E7ESU6_HUMAN" 4 1214.5826 8037.56 68268 12940 2 1214.580678 608.2986 Sodium-coupled neutral amino acid transporter 9 OS=Homo sapiens OX=9606 GN=SLC38A9 PE=1 SV=2 8.73 3148.7 - 162614 - - - -1.5857 - 0.882 0.143 - 51 1 2 0 -0.0019 11 0 0 0 4.74E+07 5.90E+03 - - - -0.2431 0.9671 230117_WJC_METTL3_WT_vs_EV_F10.13201.13201.2 0.113 16-Apr R.AFGYYGPLR[166.11].S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1052.5319 1.14 68308 13201 2 1052.529591 527.2732 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3191.4 - 33059.3 - - - -2.1805 - 0.878 0.297 - 66.6 1 2 0 -0.0023 9 0 0 0 1.22E+06 1.07E+06 - - - 0.8575 0.9831 230117_WJC_METTL3_WT_vs_EV_F10.13207.13207.2 0.00271 16-Apr R.AFGYYGPLR.S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1042.5236 1.14 68310 13207 2 1042.519568 522.2691 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3192.2 - 25734 - - - -3.8829 - 0.96 0.465 - 66.6 1 2 0 -0.004 9 0 0 0 1.22E+06 1.07E+06 - - - 2.3561 1 230117_WJC_METTL3_WT_vs_EV_F10.14184.14184.4 9.68E-06 7/126 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K.Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2674.0556 2.61 68422 14184 4 2674.047385 669.5212 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3360.4 - 15555.2 - - - -3.0882 - 1.625 0.636 - 25.7 1 2 0 -0.0083 22 0 0 0 8.08E+05 3.10E+05 - - - 4.9183 0.9943 230117_WJC_METTL3_WT_vs_EV_F10.14208.14208.2 0.0366 14-Jun R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 122.22 68425 14208 2 1000.558431 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3364.4 - 33457.5 - - - -0.9015 - 1.379 0.217 - 126.5 1 2 0 -0.0009 8 0 0 0 1.19E+08 9.72E+05 - - - 1.6127 0.9969 230117_WJC_METTL3_WT_vs_EV_F10.14675.14675.2 0.00158 26-Apr R.GVVDSEDIPLNLSR.E "sp|Q12931|TRAP1_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 6 1512.7784 173.67 68495 14675 2 1512.77687 757.3965 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.03 3442.4 - 41996.4 - - - -1.0028 - 0.994 0.436 - 46.5 1 2 0 -0.0015 14 0 0 0 5.19E+06 2.99E+04 - - - 2.2457 0.9947 230117_WJC_METTL3_WT_vs_EV_F10.14773.14773.2 0.131 16-Jul R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 18.6 68505 14773 2 1006.567815 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3459.4 - 49415.9 - - - -2.0694 - 1.441 0.31 - 102.1 1 2 0 -0.0021 9 0 0 0 2.40E+08 1.29E+07 - - - 2.3869 0.9556 230117_WJC_METTL3_WT_vs_EV_F10.14789.14789.2 0.605 16-Apr R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 18.55 68508 14789 2 1014.581743 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3462.1 - 23893.3 - - - -2.3211 - 0.822 0.301 - 39.3 1 2 0 -0.0024 9 0 0 0 2.40E+08 1.29E+07 - - - 0.6964 0.9977 230117_WJC_METTL3_WT_vs_EV_F10.15015.15015.2 0.00119 20-May K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 13.36 68540 15015 2 1204.679401 603.3481 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3499.1 - 52063.8 - - - -1.803 - 1.352 0.451 - 84 1 2 0 -0.0022 11 0 0 0 2.75E+06 2.06E+05 - - - 3.1873 0.9995 230117_WJC_METTL3_WT_vs_EV_F10.15053.15053.2 0.000324 18-Jul R.EC[160.03]LNLWGYER.V sp|Q86U44|MTA70_HUMAN 1 1338.6027 2.12 68547 15053 2 1338.601959 670.3086 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3505.4 - 33562.9 - - - -0.5319 - 1.62 0.553 - 238.8 1 2 0 -0.0007 10 0 0 0 1.05E+07 4.97E+06 - - - 4.4718 0.9988 230117_WJC_METTL3_WT_vs_EV_F10.15054.15054.2 0.0142 18-Jun R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 2.12 68548 15054 2 1348.609072 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3505.6 - 13889.6 - - - -1.3859 - 1.379 0.53 - 157.4 1 2 0 -0.0019 10 0 0 0 1.05E+07 4.97E+06 - - - 3.852 0.991 230117_WJC_METTL3_WT_vs_EV_F10.15096.15096.3 0.0276 Mar-76 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 1.89 68553 15096 3 2187.032899 730.0199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3512.4 - 0 - - - -2.2711 - 0.851 0.418 - 10.5 1 2 0 -0.005 20 0 0 0 9.71E+06 5.13E+06 - - - 2.8075 1 230117_WJC_METTL3_WT_vs_EV_F10.15108.15108.2 6.38E-08 Sep-38 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 3.28 68556 15108 2 2187.031588 1094.5262 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3514.3 - 7565.01 - - - -2.8705 - 2.359 0.667 - 180.6 1 2 0 -0.0063 20 0 0 0 3.52E+06 1.07E+06 - - - 6.0755 1 230117_WJC_METTL3_WT_vs_EV_F10.15113.15113.3 2.85E-08 Nov-76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 1.89 68558 15113 3 2198.038766 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3515.1 - 39263.9 - - - 451.8021 - 2.358 0.653 - 144.9 1 2 0 0.9926 20 0 0 0 9.71E+06 5.13E+06 - - - 7.6264 0.9992 230117_WJC_METTL3_WT_vs_EV_F10.15215.15215.2 2.34E-06 22-Sep K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 15.99 68571 15215 2 1332.738517 667.3774 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3532.5 - 63644.1 - - - -1.226 - 1.972 0.48 - 241.5 1 2 0 -0.0016 12 0 0 0 3.69E+06 2.31E+05 - - - 4.3725 0.9974 230117_WJC_METTL3_WT_vs_EV_F10.15533.15533.2 0.000226 30-May K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 999 68633 15533 2 1789.880256 895.9496 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3583.6 - 0 - - - -2.451 - 1.311 0.53 - 63.6 1 2 0 -0.0044 16 0 0 0 2.51E+06 0.00E+00 - - - 3.62 0.9913 230117_WJC_METTL3_WT_vs_EV_F10.15598.15598.2 0.204 Mar-32 K.AHTSFQISLSVSYTGSR[166.11].S sp|P01023|A2MG_HUMAN 1 1849.9198 0 68645 15598 2 1849.919028 925.9672 Alpha-2-macroglobulin OS=Homo sapiens OX=9606 GN=A2M PE=1 SV=3 8.8 3594.3 - 22790.4 - - - -0.4152 - 0.927 0.313 - 16.2 2 2 0 -0.0008 17 0 0 0 6.87E+03 2.05E+06 - - - 1.0317 0.9988 230117_WJC_METTL3_WT_vs_EV_F10.15599.15599.2 0.00134 30-May R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 16.04 68646 15599 2 1686.893205 844.4543 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3594.5 - 10365.1 - - - -0.5217 - 1.336 0.443 - 49.6 1 2 0 -0.0009 16 0 0 0 4.83E+05 3.01E+04 - - - 3.0249 0.9985 230117_WJC_METTL3_WT_vs_EV_F10.15606.15606.2 0.0232 26-Apr K.NIYVLQELDNPGAK[136.11].R "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1580.829 1.2 68647 15606 2 1580.828426 791.4218 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3595.7 - 0 - - - -0.3454 - 1.094 0.447 - 45.5 1 2 0 -0.0005 14 0 0 0 5.79E+05 4.84E+05 - - - 2.5678 0.9965 230117_WJC_METTL3_WT_vs_EV_F10.15610.15610.2 0.123 26-Mar K.NIYVLQELDNPGAK.R "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1572.8148 1.2 68648 15610 2 1572.815471 787.4147 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3596.3 - 33842 - - - 0.4444 - 0.94 0.341 - 22.2 1 2 0 0.0007 14 0 0 0 5.79E+05 4.84E+05 - - - 1.4041 0.9307 230117_WJC_METTL3_WT_vs_EV_F10.15679.15679.2 2.37 Apr-34 R.GSAAALC[160.03]NNLSVLQLPAR.N sp|Q9H977|WDR54_HUMAN 1 1853.9782 999 68663 15679 2 1853.979372 927.9964 WD repeat-containing protein 54 OS=Homo sapiens OX=9606 GN=WDR54 PE=1 SV=1 8.25 3607.5 - 23201.8 - - - 0.6505 - 1.05 0.013 - 32.8 1 2 0 0.0012 18 0 0 0 1.14E+07 0.00E+00 - - - -0.7434 0.9936 230117_WJC_METTL3_WT_vs_EV_F10.15782.15782.2 0.036 18-Apr R.FEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1252.6088 5.7 68688 15782 2 1252.60792 627.3117 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3623.7 - 54636.9 - - - -0.7041 - 1.003 0.321 - 53.4 1 2 0 -0.0009 10 0 0 0 2.08E+06 3.65E+05 - - - 1.42 0.9795 230117_WJC_METTL3_WT_vs_EV_F10.15851.15851.2 0.187 20-Mar K.MALDIEIATYR.K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1294.6591 1.48 68710 15851 2 1294.660138 648.3368 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3634.1 - 17176 - - - 0.784 - 0.784 0.223 - 25.3 1 2 0 0.001 11 0 0 0 4.06E+05 2.75E+05 - - - 0.0295 0.9727 230117_WJC_METTL3_WT_vs_EV_F10.15854.15854.2 0.0121 16-May K.GFGFVSFER.H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1044.5029 0.94 68711 15854 2 1044.50062 523.2587 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3634.5 - 64727.6 - - - -2.1647 - 1.128 0.217 - 91.4 1 2 0 -0.0023 9 0 0 0 1.82E+06 1.94E+06 - - - 0.9915 0.9897 230117_WJC_METTL3_WT_vs_EV_F10.15855.15855.2 0.0362 16-May K.GFGFVSFER[166.11].H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1054.5112 0.94 68712 15855 2 1054.509035 528.2629 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3634.6 - 68843.8 - - - -2.0066 - 1.194 0.292 - 89.6 1 2 0 -0.0021 9 0 0 0 1.82E+06 1.94E+06 - - - 1.71 0.9983 230117_WJC_METTL3_WT_vs_EV_F10.15889.15889.2 0.00463 18-May R.LFDQAFGLPR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1162.6135 1.05 68719 15889 2 1162.616081 582.314 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3640.2 - 28266.5 - - - 2.2252 - 1.149 0.354 - 100.3 1 2 0 0.0026 10 0 0 0 9.61E+05 9.18E+05 - - - 2.0425 0.8961 230117_WJC_METTL3_WT_vs_EV_F10.15973.15973.2 0.109 22-Apr R.DIISIAEDEDLR.V "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1387.6831 2.01 68732 15973 2 1387.67934 694.8488 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 3.77 3654.5 - 22227.2 - - - -2.7023 - 0.874 0.209 - 54.9 1 2 0 -0.0037 12 0 0 0 3.42E+05 1.70E+05 - - - 0.2291 0.9732 230117_WJC_METTL3_WT_vs_EV_F10.16048.16048.2 0.0657 22-Apr K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 999 68747 16048 2 1252.750043 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3666.8 - 18350.4 - - - -0.2227 - 0.909 0.183 - 46.2 1 2 0 -0.0003 12 0 0 0 2.54E+06 0.00E+00 - - - 0.1415 0.9862 230117_WJC_METTL3_WT_vs_EV_F10.16270.16270.2 0.0728 18-Mar R.FEELC[160.03]ADLFR.G "sp|P34931|HS71L_HUMAN,tr|Q53FA3|Q53FA3_HUMAN" 2 1298.5965 34.71 68795 16270 2 1298.597511 650.3055 Heat shock 70 kDa protein 1-like OS=Homo sapiens OX=9606 GN=HSPA1L PE=1 SV=2 4.14 3702.9 - 14763.7 - - - 0.7608 - 0.703 0.304 - 30.1 1 2 0 0.001 10 0 0 0 5.20E+05 1.50E+04 - - - 0.3024 0.9836 230117_WJC_METTL3_WT_vs_EV_F10.16353.16353.2 0.00811 24-Apr K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 0.61 68811 16353 2 1600.737352 801.3794 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3716.4 - 12343.6 - - - -4.3467 - 0.993 0.5 - 48.9 1 2 0 -0.007 13 0 0 0 3.61E+05 5.89E+05 - - - 2.7138 0.9986 230117_WJC_METTL3_WT_vs_EV_F10.16389.16389.2 0.0141 14-Apr K.IPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1059.5502 1.27 68823 16389 2 1059.549791 530.7824 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3721.7 - 60091.1 - - - -0.353 - 1.112 0.447 - 96.5 1 2 0 -0.0004 8 0 0 0 2.23E+07 1.75E+07 - - - 2.6626 0.9885 230117_WJC_METTL3_WT_vs_EV_F10.16393.16393.2 0.0428 14-May K.IPDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1069.5584 1.27 68825 16393 2 1069.556252 535.7865 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3722.2 - 149047 - - - -2.041 - 1.085 0.318 - 71 1 2 0 -0.0022 8 0 0 0 2.23E+07 1.75E+07 - - - 1.6351 0.9977 230117_WJC_METTL3_WT_vs_EV_F10.16417.16417.2 0.0521 20-May K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 241.36 68831 16417 2 1276.704038 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3726.1 - 13416.6 - - - 1.0457 - 1.11 0.312 - 68.6 1 2 0 0.0013 11 0 0 0 7.32E+06 3.03E+04 - - - 1.6273 0.9998 230117_WJC_METTL3_WT_vs_EV_F10.16514.16514.3 4.01E-05 Aug-76 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 2.04 68845 16514 3 2197.084682 733.3694 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3742.2 - 32909.9 - - - -0.7164 - 1.704 0.528 - 64.5 1 2 0 -0.0016 20 0 0 0 8.61E+06 4.23E+06 - - - 5.7193 0.9708 230117_WJC_METTL3_WT_vs_EV_F10.16564.16564.2 0.304 30-Jun R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 10.86 68854 16564 2 1549.8779 775.9487 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3750.4 - 7864.48 - - - -3.1564 - 1.397 0.212 - 114.2 1 2 0 -0.0049 16 0 0 0 1.77E+06 1.63E+05 - - - 1.4273 0.9735 230117_WJC_METTL3_WT_vs_EV_F10.16656.16656.2 0.536 20-Mar R.AFITNIPFDVK.W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1263.6863 2.9 68882 16656 2 1263.684484 632.8504 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3764.8 - 19474.7 - - - -1.4561 - 0.743 0.331 - 36.1 1 2 0 -0.0018 11 0 0 0 2.02E+06 6.98E+05 - - - 0.6816 0.9959 230117_WJC_METTL3_WT_vs_EV_F10.16661.16661.2 0.0832 24-Mar K.ELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1702.7627 2.28 68885 16661 2 1702.763032 852.3886 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.14 3765.6 - 27433.2 - - - 0.1732 - 0.746 0.416 - 25.8 1 2 0 0.0003 13 0 0 0 6.44E+05 2.82E+05 - - - 1.3614 0.9135 230117_WJC_METTL3_WT_vs_EV_F10.16783.16783.2 0.713 18-Apr K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.69 68918 16783 2 1176.718827 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3784.9 - 111505 - - - -1.7829 - 1.073 0.137 - 44 4 2 0 -0.0021 10 0 0 0 7.67E+06 4.55E+06 - - - -0.02 0.9991 230117_WJC_METTL3_WT_vs_EV_F10.16785.16785.2 0.00075 22-Jul R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 31.22 68919 16785 2 1603.763099 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3785.1 - 97654.7 - - - -0.5244 - 1.419 0.457 - 140.6 1 2 0 -0.0008 12 0 0 0 1.96E+08 6.26E+06 - - - 3.3369 0.9998 230117_WJC_METTL3_WT_vs_EV_F10.16801.16801.3 2.43E-07 Oct-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 37.02 68924 16801 3 1603.760878 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3787.5 - 119428 - - - -1.9093 - 1.792 0.589 - 116.4 1 2 0 -0.0031 12 0 0 0 2.88E+07 7.77E+05 - - - 6.7228 0.895 230117_WJC_METTL3_WT_vs_EV_F10.16852.16852.2 0.0972 16-Jun K.EIIDLVLDR.L "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 9 1084.6128 4.57 68940 16852 2 1084.610051 543.3137 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.03 3795.1 - 14738.2 - - - -2.5576 - 1.419 0.033 - 118.2 2 2 0 -0.0028 9 0 0 0 2.61E+06 5.71E+05 - - - 0.1618 0.9543 230117_WJC_METTL3_WT_vs_EV_F10.16921.16921.2 0.0665 26-Mar R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.93 68960 16921 2 1487.771369 744.8959 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3805.6 - 29989.3 - - - -3.963 - 0.979 0.353 - 26.9 2 2 0 -0.0059 14 0 0 0 4.03E+05 2.09E+05 - - - 1.4587 0.9988 230117_WJC_METTL3_WT_vs_EV_F10.16982.16982.2 0.000126 22-Nov R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 36.82 68973 16982 2 1603.761003 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3815.4 - 323973 - - - -1.8313 - 1.753 0.537 - 335.3 1 2 0 -0.0029 12 0 0 0 1.14E+08 3.09E+06 - - - 4.4833 0.9993 230117_WJC_METTL3_WT_vs_EV_F10.16996.16996.3 1.50E-06 Dec-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 55.97 68975 16996 3 1603.756898 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3817.7 - 637498 - - - -4.3909 - 2.114 0.608 - 182.9 1 2 0 -0.007 12 0 0 0 1.58E+07 2.82E+05 - - - 7.3916 0.9711 230117_WJC_METTL3_WT_vs_EV_F10.17011.17011.2 0.0813 22-Apr R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 36.71 68981 17011 2 1613.770225 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3820 - 98915.4 - - - -1.23 - 0.833 0.265 - 40.8 1 2 0 -0.002 12 0 0 0 1.11E+08 3.03E+06 - - - 0.5169 0.9502 230117_WJC_METTL3_WT_vs_EV_F10.17058.17058.2 0.0034 20-Jun K.WYLENVYPELR[166.11].V sp|Q10471|GALT2_HUMAN 1 1490.7433 0.88 68990 17058 2 1490.732062 746.3789 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3827.3 - 16363.1 - - - -7.562 - 1.546 0.484 - 151.7 1 2 0 -0.0113 11 0 0 0 1.45E+06 1.65E+06 - - - 3.7909 0.9982 230117_WJC_METTL3_WT_vs_EV_F10.17114.17114.2 9.02E-05 28-Nov K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 3.11 69009 17114 2 1658.904909 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3835.8 - 78373.7 - - - -2.5065 - 2.294 0.461 - 437.4 1 2 0 -0.0042 15 0 0 0 5.12E+06 1.65E+06 - - - 4.486 0.9966 230117_WJC_METTL3_WT_vs_EV_F10.17118.17118.2 5.85E-05 28-Jul K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 3.11 69011 17118 2 1666.917705 834.4689 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3836.4 - 22780.4 - - - -3.3367 - 1.836 0.502 - 164.8 1 2 0 -0.0056 15 0 0 0 5.12E+06 1.65E+06 - - - 4.2408 0.8835 230117_WJC_METTL3_WT_vs_EV_F10.17178.17178.2 1.75 20-Mar K.ELGIWEPLAVK.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1253.702 26.57 69032 17178 2 1253.69941 627.8583 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3845.1 - 17163.7 - - - -2.0451 - 0.833 0.198 - 32 2 2 0 -0.0026 11 0 0 0 2.37E+06 8.93E+04 - - - -0.1262 0.999 230117_WJC_METTL3_WT_vs_EV_F10.17181.17181.2 2.08E-05 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 32.66 69034 17181 2 1603.761468 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3845.6 - 924887 - - - -1.5414 - 1.691 0.538 - 232.9 1 2 0 -0.0025 12 0 0 0 1.15E+08 3.52E+06 - - - 4.3961 0.9986 230117_WJC_METTL3_WT_vs_EV_F10.17197.17197.3 5.95E-05 Aug-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 68.65 69039 17197 3 1603.759099 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3847.9 - 255426 - - - -3.0185 - 1.48 0.475 - 68.2 1 2 0 -0.0048 12 0 0 0 1.57E+07 2.29E+05 - - - 4.9211 0.9961 230117_WJC_METTL3_WT_vs_EV_F10.17208.17208.2 0.000173 26-Jun R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 0.89 69042 17208 2 1669.890108 835.9552 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3849.7 - 29134 - - - -3.4864 - 1.584 0.534 - 110.9 1 2 0 -0.0058 14 0 0 0 2.21E+06 2.47E+06 - - - 4.1375 1 230117_WJC_METTL3_WT_vs_EV_F10.17215.17215.2 1.33E-06 26-Jul R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 0.89 69043 17215 2 1661.87821 831.9481 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3851 - 161393 - - - -2.1181 - 1.81 0.622 - 150.8 1 2 0 -0.0035 14 0 0 0 2.21E+06 2.47E+06 - - - 5.1229 0.9995 230117_WJC_METTL3_WT_vs_EV_F10.17231.17231.3 8.41E-05 8/120 K.ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK.G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3054.4869 1.54 69052 17231 3 3054.478754 1019.1696 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3853.2 - 13668.6 - - - -2.6734 - 1.921 0.531 - 42.2 1 2 0 -0.0082 31 0 0 0 7.44E+05 4.82E+05 - - - 5.9598 0.9893 230117_WJC_METTL3_WT_vs_EV_F10.17239.17239.2 0.00349 26-May K.LVINGNPITIFQER.D sp|P04406|G3P_HUMAN 1 1612.8937 1.53 69053 17239 2 1612.887715 807.4541 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3854.5 - 11553 - - - -3.7051 - 1.347 0.402 - 61.9 1 2 0 -0.006 14 0 0 0 1.90E+06 1.24E+06 - - - 2.7558 0.9921 230117_WJC_METTL3_WT_vs_EV_F10.17245.17245.2 0.0495 26-Apr K.LVINGNPITIFQER[166.11].D sp|P04406|G3P_HUMAN 1 1622.902 1.53 69057 17245 2 1622.899744 812.4583 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3855.3 - 29316.2 - - - -1.3661 - 1.187 0.287 - 41.5 1 2 0 -0.0022 14 0 0 0 1.90E+06 1.24E+06 - - - 1.5903 0.9949 230117_WJC_METTL3_WT_vs_EV_F10.17287.17287.2 0.0502 28-May R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 4.68 69066 17287 2 1700.896752 851.4565 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3861.9 - 39460.7 - - - -1.0289 - 1.12 0.335 - 59.7 1 2 0 -0.0018 15 0 0 0 3.19E+06 6.82E+05 - - - 1.7934 0.9459 230117_WJC_METTL3_WT_vs_EV_F10.17295.17295.2 0.0425 20-Mar R.DSLIFLVDASK.A sp|P12956|XRCC6_HUMAN 1 1206.6496 1.56 69068 17295 2 1206.646324 604.3321 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.21 3863 - 31838 - - - -2.7183 - 0.743 0.337 - 23.3 1 2 0 -0.0033 11 0 0 0 2.45E+06 1.57E+06 - - - 0.7254 0.9339 230117_WJC_METTL3_WT_vs_EV_F10.17370.17370.3 0.107 Mar-56 R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 1.39 69084 17370 3 2001.968816 668.3319 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3874.9 - 77879.6 - - - -2.4561 - 0.865 0.295 - 8.8 1 2 0 -0.0049 15 0 0 0 2.80E+06 2.01E+06 - - - 1.4492 1 230117_WJC_METTL3_WT_vs_EV_F10.17379.17379.2 1.49E-05 22-Oct R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 58 69088 17379 2 1603.75985 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3876.2 - 176341 - - - -2.5503 - 1.936 0.568 - 256.2 1 2 0 -0.0041 12 0 0 0 8.46E+07 1.46E+06 - - - 4.9732 0.9052 230117_WJC_METTL3_WT_vs_EV_F10.17482.17482.2 0.19 26-Mar K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 0.75 69107 17482 2 1651.930887 826.9731 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3893.2 - 15557.1 - - - -0.4601 - 0.758 0.159 - 24.7 2 2 0 -0.0008 14 0 0 0 6.72E+05 9.01E+05 - - - -0.6146 0.9994 230117_WJC_METTL3_WT_vs_EV_F10.17502.17502.3 8.14E-05 Jun-68 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.84 69113 17502 3 1926.00218 643.0084 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3896.2 - 11240.9 - - - -0.5914 - 1.34 0.444 - 38.9 1 2 0 -0.0011 18 0 0 0 3.43E+05 4.10E+05 - - - 4.2186 0.9996 230117_WJC_METTL3_WT_vs_EV_F10.17564.17564.2 0.00152 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 93.07 69124 17564 2 1603.764771 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3906.3 - 167992 - - - 0.5182 - 1.541 0.501 - 164.6 1 2 0 0.0008 12 0 0 0 1.94E+07 2.09E+05 - - - 3.8789 0.9789 230117_WJC_METTL3_WT_vs_EV_F10.17604.17604.2 0.61 22-Apr K.IILDLISESPIK.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1339.7963 1.25 69136 17604 2 1339.796076 670.9054 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3912.3 - 12124.5 - - - -0.1441 - 1.113 0.129 - 43.3 1 2 0 -0.0002 12 0 0 0 9.50E+05 7.60E+05 - - - 0.2754 0.9962 230117_WJC_METTL3_WT_vs_EV_F10.17611.17611.2 0.0181 22-May K.IILDLISESPIK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1347.8105 1.25 69139 17611 2 1347.809521 674.9125 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3913.4 - 8659.15 - - - -0.7034 - 1.364 0.272 - 63.8 1 2 0 -0.0009 12 0 0 0 9.50E+05 7.60E+05 - - - 1.8665 0.9961 230117_WJC_METTL3_WT_vs_EV_F10.17619.17619.2 0.00357 24-May R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.15 69142 17619 2 1438.778512 720.3983 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3914.6 - 15556.5 - - - -2.4354 - 1.333 0.441 - 93.8 1 2 0 -0.0035 13 0 0 0 8.67E+05 7.52E+05 - - - 3.0348 1 230117_WJC_METTL3_WT_vs_EV_F10.17627.17627.2 2.59E-08 22-Sep R.YFPTQALNFAFK.D "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 1445.7343 1.63 69145 17627 2 1445.73314 723.8744 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.59 3915.8 - 18241.2 - - - -0.828 - 1.853 0.552 - 222.2 1 2 0 -0.0012 12 0 0 0 2.36E+06 1.45E+06 - - - 4.7406 0.9965 230117_WJC_METTL3_WT_vs_EV_F10.17628.17628.2 8.74E-05 22-May R.YFPTQALNFAFK[136.11].D "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 1453.7485 1.63 69146 17628 2 1453.744337 727.8815 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.59 3915.9 - 22900.9 - - - -2.8891 - 1.156 0.57 - 69 1 2 0 -0.0042 12 0 0 0 2.36E+06 1.45E+06 - - - 3.6311 0.9958 230117_WJC_METTL3_WT_vs_EV_F10.17634.17634.2 0.00039 16-Jun R.FWYFVSQLK.K "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1216.6281 0.74 69148 17634 2 1216.624489 609.3213 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.59 3916.8 - 101827 - - - -2.9524 - 1.237 0.502 - 115.9 1 2 0 -0.0036 9 0 0 0 1.22E+06 1.65E+06 - - - 3.363 0.8661 230117_WJC_METTL3_WT_vs_EV_F10.17661.17661.2 2.24 22-Apr K.WLAPDGLIFPDR[166.11].A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1408.7379 0.82 69158 17661 2 1408.734019 705.3762 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3920.8 - 23908 - - - -2.7237 - 0.937 0.178 - 52.2 2 2 0 -0.0038 12 0 0 0 1.38E+06 1.68E+06 - - - 0.0488 0.9998 230117_WJC_METTL3_WT_vs_EV_F10.17667.17667.3 0.000652 5/112 R.RAEQDSTTVAAFASSLVSGLNSSASEPAK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2880.4101 3.97 69160 17667 3 2880.409587 961.144 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3921.8 - 8292.87 - - - -0.1816 - 1.435 0.501 - 18.1 1 2 0 -0.0005 29 0 0 0 4.90E+05 1.23E+05 - - - 4.9564 0.8989 230117_WJC_METTL3_WT_vs_EV_F10.17671.17671.2 0.923 22-Apr K.WLAPDGLIFPDR.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1398.7296 0.82 69161 17671 2 1398.725683 700.3721 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3922.4 - 31016.3 - - - -2.7904 - 0.916 0.2 - 42.9 1 2 0 -0.0039 12 0 0 0 1.38E+06 1.68E+06 - - - 0.2861 0.9962 230117_WJC_METTL3_WT_vs_EV_F10.17672.17672.2 0.00305 30-Apr K.LFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1783.8992 1.33 69162 17672 2 1783.896955 892.9569 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3922.5 - 10528.3 - - - -1.2753 - 1.18 0.375 - 27.4 1 2 0 -0.0023 16 0 0 0 8.62E+05 6.46E+05 - - - 2.217 0.9934 230117_WJC_METTL3_WT_vs_EV_F10.17675.17675.2 3.00E-05 30-Apr K.LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1793.9075 1.33 69163 17675 2 1793.90261 897.961 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3923 - 14954.6 - - - -2.7259 - 1.078 0.459 - 34.1 1 2 0 -0.0049 16 0 0 0 8.62E+05 6.46E+05 - - - 2.6143 0.8708 230117_WJC_METTL3_WT_vs_EV_F10.17684.17684.2 0.00427 18-Apr Y.C[160.03]SYGSWDLFR.E "sp|Q969W1|ZDH16_HUMAN,tr|B1AMT9|B1AMT9_HUMAN,tr|H0Y536|H0Y536_HUMAN,tr|H0Y6E9|H0Y6E9_HUMAN" 4 1289.5499 999 69167 17684 2 1289.553553 645.7822 Palmitoyltransferase ZDHHC16 OS=Homo sapiens OX=9606 GN=ZDHHC16 PE=1 SV=1 5.83 3924.3 - 0 - - - 2.8273 - 0.926 0.465 - 77.8 1 1 0 0.0036 10 0 0 0 1.50E+05 0.00E+00 - - - 2.2597 0.9956 230117_WJC_METTL3_WT_vs_EV_F10.17729.17729.2 0.068 30-Mar K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 0.99 69179 17729 2 1797.913486 899.9647 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3931.1 - 39961.4 - - - -0.7753 - 0.859 0.422 - 24.1 1 2 0 -0.0014 16 0 0 0 1.84E+06 1.85E+06 - - - 1.7838 1 230117_WJC_METTL3_WT_vs_EV_F10.17735.17735.2 4.01E-08 30-Oct K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 0.99 69185 17735 2 1807.918274 904.9689 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3931.9 - 36160.2 - - - -2.697 - 2.431 0.615 - 244.5 1 2 0 -0.0049 16 0 0 0 1.84E+06 1.85E+06 - - - 5.7658 0.9873 230117_WJC_METTL3_WT_vs_EV_F10.17786.17786.2 0.00522 14-Jun R.GFGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 921.5204 1.16 69197 17786 2 921.518061 461.7675 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3940.3 - 93148.3 - - - -2.5111 - 1.105 0.334 - 124.9 1 2 0 -0.0023 8 0 0 0 4.09E+06 3.52E+06 - - - 1.8083 0.9963 230117_WJC_METTL3_WT_vs_EV_F10.17789.17789.2 0.000509 14-Jul R.GFGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 913.5062 1.16 69198 17789 2 913.503766 457.7604 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3940.7 - 140168 - - - -2.6371 - 1.422 0.432 - 160.8 1 2 0 -0.0024 8 0 0 0 4.09E+06 3.52E+06 - - - 3.2928 0.993 230117_WJC_METTL3_WT_vs_EV_F10.17790.17790.3 0.0325 May-60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 999 69199 17790 3 1796.002053 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3940.8 - 39670.9 - - - -1.2867 - 1.11 0.333 - 26.7 1 2 0 -0.0023 16 0 0 0 1.73E+06 0.00E+00 - - - 2.5198 0.9984 230117_WJC_METTL3_WT_vs_EV_F10.17805.17805.2 8.34E-06 22-Sep K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 999 69201 17805 2 1459.789401 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3943 - 41910.9 - - - -1.9489 - 1.886 0.44 - 348.9 1 2 0 -0.0028 12 0 0 0 3.41E+06 0.00E+00 - - - 3.9593 0.9994 230117_WJC_METTL3_WT_vs_EV_F10.17857.17857.4 4.73E-06 8/204 R.KIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 3974.1279 3.28 69217 17857 4 3974.118761 994.5392 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.01 3950.8 - 35026.5 - - - -2.2969 - 1.975 0.55 - 18.8 1 2 0 -0.0091 35 0 0 0 4.36E+05 1.33E+05 - - - 4.2124 0.9995 230117_WJC_METTL3_WT_vs_EV_F10.17867.17867.2 0.00641 20-Aug K.ILDVEIIFNER[166.11].G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1369.7481 1.27 69219 17867 2 1369.751639 685.8813 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3952.3 - 37621.3 - - - 2.5932 - 1.822 0.438 - 267.3 1 2 0 0.0036 11 0 0 0 8.50E+05 6.69E+05 - - - 3.8979 0.998 230117_WJC_METTL3_WT_vs_EV_F10.17877.17877.2 0.0998 20-Aug K.ILDVEIIFNER.G "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|F5H0M1|F5H0M1_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1359.7398 1.27 69221 17877 2 1359.73683 680.8772 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.14 3954 - 31841 - - - -2.1967 - 1.719 0.45 - 189.1 1 2 0 -0.003 11 0 0 0 8.50E+05 6.69E+05 - - - 3.8293 0.9495 230117_WJC_METTL3_WT_vs_EV_F10.17910.17910.2 0.237 26-Feb K.VVIGMDVAASEFFR.S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1539.7756 1.95 69234 17910 2 1539.772883 770.8951 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.37 3958.8 - 19028.1 - - - -1.7321 - 0.719 0.317 - 13.5 3 2 0 -0.0027 14 0 0 0 2.86E+05 1.47E+05 - - - 0.3405 0.984 230117_WJC_METTL3_WT_vs_EV_F10.17920.17920.2 0.251 Feb-34 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 32.52 69240 17920 2 1911.94566 956.9806 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3960.1 - 26349.7 - - - -0.4786 - 0.809 0.365 - 6.5 23 2 0 -0.0009 18 0 0 0 4.07E+05 1.25E+04 - - - 0.6072 1 230117_WJC_METTL3_WT_vs_EV_F10.17927.17927.4 1.20E-08 12/162 R.PHNVQPNWITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 3130.6312 2.39 69242 17927 4 3130.627832 783.6651 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.14 3961.2 - 50534.4 - - - -1.0809 - 2.816 0.668 - 55.2 1 1 0 -0.0034 28 0 0 0 2.39E+06 1.00E+06 - - - 5.3608 1 230117_WJC_METTL3_WT_vs_EV_F10.17961.17961.4 1.79E-11 16/198 K.IELFGRPHNVQPNWITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 3846.0329 2.64 69251 17961 4 3846.02346 962.5155 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.26 3966.5 - 47080 - - - -2.4612 - 3.809 0.691 - 83.5 1 2 0 -0.0095 34 0 0 0 1.45E+06 5.50E+05 - - - 5.6367 0.9999 230117_WJC_METTL3_WT_vs_EV_F10.18050.18050.3 4.89E-08 Aug-60 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 999 69281 18050 3 1992.967739 665.3304 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3979.7 - 26094.1 - - - -0.8214 - 2.005 0.634 - 79.8 1 2 0 -0.0016 16 0 0 0 1.04E+06 0.00E+00 - - - 7.3929 1 230117_WJC_METTL3_WT_vs_EV_F10.18071.18071.3 3.25E-08 19/84 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.43 69287 18071 3 2364.323305 789.1161 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3982.9 - 143449 - - - -1.3205 - 3.951 0.6 - 365.2 1 2 0 -0.0031 22 0 0 0 2.26E+06 1.58E+06 - - - 8.486 1 230117_WJC_METTL3_WT_vs_EV_F10.18074.18074.3 3.68E-07 13/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.43 69288 18074 3 2382.339746 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3983.3 - 88168.9 - - - -3.8412 - 2.902 0.674 - 190.4 1 2 0 -0.0092 22 0 0 0 2.26E+06 1.58E+06 - - - 8.5778 0.9517 230117_WJC_METTL3_WT_vs_EV_F10.18094.18094.2 1.05 22-Apr K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 1.35 69293 18094 2 1336.846046 669.4314 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3986.2 - 7788.83 - - - -1.6449 - 0.992 0.196 - 57.3 2 2 0 -0.0022 12 0 0 0 7.21E+05 5.35E+05 - - - 0.3324 0.9868 230117_WJC_METTL3_WT_vs_EV_F10.18095.18095.2 1.62 22-Apr K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 1.35 69294 18095 2 1344.859005 673.4385 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3986.4 - 14204 - - - -2.5579 - 0.937 0.397 - 59.7 1 2 0 -0.0034 12 0 0 0 7.21E+05 5.35E+05 - - - 1.8009 0.9869 230117_WJC_METTL3_WT_vs_EV_F10.18126.18126.2 0.000384 22-Mar K.TSDLIVLGLPWK.T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1340.7704 3.02 69305 18126 2 1340.766575 671.3925 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3991 - 20449.8 - - - -2.8439 - 0.745 0.502 - 30.7 1 2 0 -0.0038 12 0 0 0 3.06E+05 1.01E+05 - - - 1.973 0.9562 230117_WJC_METTL3_WT_vs_EV_F10.18136.18136.3 0.173 Apr-60 K.IFEIFGPVAHPFYVLR.F sp|Q96HR8|NAF1_HUMAN 1 1904.0349 2.02 69308 18136 3 1904.035826 635.6856 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 6.75 3992.5 - 28485.1 - - - 0.4989 - 0.891 0.213 - 22.2 1 2 0 0.0009 16 0 0 0 6.64E+05 3.28E+05 - - - 0.6183 0.9999 230117_WJC_METTL3_WT_vs_EV_F10.18160.18160.3 3.14E-05 Sep-52 R.HPYFYAPELLFFAK.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 1741.8868 999 69317 18160 3 1741.886287 581.6362 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6.75 3996.1 - 51268.7 - - - -0.3031 - 2.13 0.581 - 155.6 1 2 0 -0.0005 14 0 0 0 7.61E+05 0.00E+00 - - - 7.0268 0.8766 230117_WJC_METTL3_WT_vs_EV_F10.18180.18180.3 5.52E-05 20/100 H.NVQPNWITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 2896.5195 -1 69322 18180 3 2896.516211 966.5138 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3999.4 - 345396 - - - -1.1497 - 2.604 0.381 - 211.9 1 1 0 -0.0033 26 0 0 0 0.00E+00 0.00E+00 - - - 4.9887